From 47812c97deb94eb46d34f0af51818b8b43d94f19 Mon Sep 17 00:00:00 2001 From: Andreas Tille Date: Sun, 18 Jun 2017 20:41:36 +0100 Subject: [PATCH 1/1] Import bcftools_1.4.1.orig.tar.gz [dgit import orig bcftools_1.4.1.orig.tar.gz] --- AUTHORS | 16 + HMM.c | 494 ++ HMM.h | 133 + INSTALL | 67 + LICENSE | 725 +++ Makefile | 260 + NEWS | 236 + README | 5 + bam2bcf.c | 857 +++ bam2bcf.h | 138 + bam2bcf_indel.c | 470 ++ bam_sample.c | 393 ++ bam_sample.h | 50 + bcftools.h | 73 + bin.c | 104 + bin.h | 65 + call.h | 127 + ccall.c | 337 + consensus.c | 688 ++ convert.c | 1376 ++++ convert.h | 44 + csq.c | 3824 +++++++++++ doc/bcftools.1 | 4810 ++++++++++++++ doc/bcftools.html | 2683 ++++++++ doc/bcftools.txt | 2810 ++++++++ doc/docbook-xsl.css | 355 + em.c | 259 + filter.c | 1867 ++++++ filter.h | 52 + gvcf.c | 227 + gvcf.h | 41 + hclust.c | 400 ++ hclust.h | 77 + khash_str2str.h | 106 + kheap.h | 171 + kmin.c | 209 + kmin.h | 46 + main.c | 274 + mcall.c | 1579 +++++ misc/color-chrs.pl | 528 ++ 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License + + Copyright (c) 2014-2015 Genome Research Ltd. + + Author: Petr Danecek + + Permission is hereby granted, free of charge, to any person obtaining a copy + of this software and associated documentation files (the "Software"), to deal + in the Software without restriction, including without limitation the rights + to use, copy, modify, merge, publish, distribute, sublicense, and/or sell + copies of the Software, and to permit persons to whom the Software is + furnished to do so, subject to the following conditions: + + The above copyright notice and this permission notice shall be included in + all copies or substantial portions of the Software. + + THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR + IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, + FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE + AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER + LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, + OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN + THE SOFTWARE. + + */ + +#include +#include +#include +#include +#include +#include "HMM.h" + +typedef struct +{ + int nstates; // number of hmm's states + int isite; // take snapshot at i-th position + uint32_t pos; // i-th site's position + double *vit_prob; // viterbi probabilities, NULL for uniform probs + double *fwd_prob; // transition probabilities + double *bwd_prob; // transition probabilities +} +snapshot_t; + +struct _hmm_t +{ + int nstates; // number of states + + double *vprob, *vprob_tmp; // viterbi probs [nstates] + uint8_t *vpath; // viterbi path [nstates*nvpath] + double *bwd, *bwd_tmp; // bwd probs [nstates] + double *fwd; // fwd probs [nstates*(nfwd+1)] + int nvpath, nfwd; + + int ntprob_arr; // number of pre-calculated tprob matrices + double *curr_tprob, *tmp; // Temporary arrays; curr_tprob is short lived, valid only for + // one site (that is, one step of Viterbi algorithm) + double *tprob_arr; // Array of transition matrices, precalculated to ntprob_arr + // positions. The first matrix is the initial tprob matrix + // set by hmm_init() or hmm_set_tprob() + set_tprob_f set_tprob; // Optional user function to set / modify transition probabilities + // at each site (one step of Viterbi algorithm) + void *set_tprob_data; + snapshot_t init; // Initial state probabilities. Set isite=1 when site should be used + snapshot_t *snapshot; +}; + +uint8_t *hmm_get_viterbi_path(hmm_t *hmm) { return hmm->vpath; } +double *hmm_get_tprob(hmm_t *hmm) { return hmm->tprob_arr; } +int hmm_get_nstates(hmm_t *hmm) { return hmm->nstates; } +double *hmm_get_fwd_bwd_prob(hmm_t *hmm) { return hmm->fwd; } + +static inline void multiply_matrix(int n, double *a, double *b, double *dst, double *tmp) +{ + double *out = dst; + if ( a==dst || b==dst ) + out = tmp; + + int i,j,k; + for (i=0; iinit.isite = 0; + hmm->init.pos = 0; + if ( !hmm->init.vit_prob ) + hmm->init.vit_prob = (double*) malloc(sizeof(double)*hmm->nstates); + if ( !hmm->init.fwd_prob ) + hmm->init.fwd_prob = (double*) malloc(sizeof(double)*hmm->nstates); + if ( !hmm->init.bwd_prob ) + hmm->init.bwd_prob = (double*) malloc(sizeof(double)*hmm->nstates); + + int i; + if ( probs ) + { + memcpy(hmm->init.vit_prob,probs,sizeof(double)*hmm->nstates); + double sum = 0; + for (i=0; instates; i++) sum += hmm->init.vit_prob[i]; + for (i=0; instates; i++) hmm->init.vit_prob[i] /= sum; + } + else + for (i=0; instates; i++) hmm->init.vit_prob[i] = 1./hmm->nstates; + + memcpy(hmm->init.fwd_prob,hmm->init.vit_prob,sizeof(double)*hmm->nstates); + memcpy(hmm->init.bwd_prob,hmm->init.vit_prob,sizeof(double)*hmm->nstates); +} +hmm_t *hmm_init(int nstates, double *tprob, int ntprob) +{ + hmm_t *hmm = (hmm_t*) calloc(1,sizeof(hmm_t)); + hmm->nstates = nstates; + hmm->curr_tprob = (double*) malloc(sizeof(double)*nstates*nstates); + hmm->tmp = (double*) malloc(sizeof(double)*nstates*nstates); + hmm_set_tprob(hmm, tprob, ntprob); + hmm_init_states(hmm, NULL); + return hmm; +} + +void *hmm_snapshot(hmm_t *hmm, void *_snapshot, int isite) +{ + snapshot_t *snapshot = (snapshot_t*) _snapshot; + if ( snapshot && snapshot->nstates!=hmm->nstates ) + { + free(snapshot); + snapshot = NULL; + } + if ( !snapshot ) + { + // Allocate the snapshot as a single memory block so that it can be + // free()-ed by the user. So make sure the arrays are aligned.. + size_t str_size = sizeof(snapshot_t); + size_t dbl_size = sizeof(double); + size_t pad_size = (dbl_size - str_size % dbl_size) % dbl_size; + uint8_t *mem = (uint8_t*) malloc(str_size + pad_size + dbl_size*2*hmm->nstates); + snapshot = (snapshot_t*) mem; + snapshot->nstates = hmm->nstates; + snapshot->vit_prob = (double*) (mem + str_size + pad_size); + snapshot->fwd_prob = snapshot->vit_prob + hmm->nstates; + } + snapshot->isite = isite; + hmm->snapshot = snapshot; + return snapshot; +} +void hmm_restore(hmm_t *hmm, void *_snapshot) +{ + snapshot_t *snapshot = (snapshot_t*) _snapshot; + if ( !snapshot ) + { + hmm->init.isite = 0; + return; + } + hmm->init.isite = 1; + hmm->init.pos = snapshot->pos; + memcpy(hmm->init.vit_prob,snapshot->vit_prob,sizeof(double)*hmm->nstates); + memcpy(hmm->init.fwd_prob,snapshot->fwd_prob,sizeof(double)*hmm->nstates); +} + +void hmm_set_tprob(hmm_t *hmm, double *tprob, int ntprob) +{ + hmm->ntprob_arr = ntprob; + if ( ntprob<=0 ) ntprob = 1; + + if ( !hmm->tprob_arr ) + hmm->tprob_arr = (double*) malloc(sizeof(double)*hmm->nstates*hmm->nstates*ntprob); + + memcpy(hmm->tprob_arr,tprob,sizeof(double)*hmm->nstates*hmm->nstates); + + int i; + for (i=1; instates, hmm->tprob_arr, hmm->tprob_arr+(i-1)*hmm->nstates*hmm->nstates, hmm->tprob_arr+i*hmm->nstates*hmm->nstates, hmm->tmp); +} + +void hmm_set_tprob_func(hmm_t *hmm, set_tprob_f set_tprob, void *data) +{ + hmm->set_tprob = set_tprob; + hmm->set_tprob_data = data; +} + +static void _set_tprob(hmm_t *hmm, int pos_diff) +{ + assert( pos_diff>=0 ); + + int i, n; + + n = hmm->ntprob_arr ? pos_diff % hmm->ntprob_arr : 0; // n-th precalculated matrix + memcpy(hmm->curr_tprob, hmm->tprob_arr+n*hmm->nstates*hmm->nstates, sizeof(*hmm->curr_tprob)*hmm->nstates*hmm->nstates); + + if ( hmm->ntprob_arr > 0 ) + { + n = pos_diff / hmm->ntprob_arr; // number of full blocks to jump + for (i=0; instates, hmm->tprob_arr+(hmm->ntprob_arr-1)*hmm->nstates*hmm->nstates, hmm->curr_tprob, hmm->curr_tprob, hmm->tmp); + } +} + +void hmm_run_viterbi(hmm_t *hmm, int n, double *eprobs, uint32_t *sites) +{ + // Init arrays when run for the first time + if ( hmm->nvpath < n ) + { + hmm->nvpath = n; + hmm->vpath = (uint8_t*) realloc(hmm->vpath, sizeof(uint8_t)*hmm->nvpath*hmm->nstates); + } + if ( !hmm->vprob ) + { + hmm->vprob = (double*) malloc(sizeof(double)*hmm->nstates); + hmm->vprob_tmp = (double*) malloc(sizeof(double)*hmm->nstates); + } + + // Init all states with equal likelihood + int i,j, nstates = hmm->nstates; + memcpy(hmm->vprob, hmm->init.vit_prob, sizeof(*hmm->init.vit_prob)*nstates); + uint32_t prev_pos = hmm->init.isite ? hmm->init.pos : sites[0]; + + // Run Viterbi + for (i=0; ivpath[i*nstates]; + double *eprob = &eprobs[i*nstates]; + + int pos_diff = sites[i] == prev_pos ? 0 : sites[i] - prev_pos - 1; + _set_tprob(hmm, pos_diff); + if ( hmm->set_tprob ) hmm->set_tprob(hmm, prev_pos, sites[i], hmm->set_tprob_data, hmm->curr_tprob); + prev_pos = sites[i]; + + double vnorm = 0; + for (j=0; jvprob[k] * MAT(hmm->curr_tprob,hmm->nstates,j,k); + if ( vmax < pval ) { vmax = pval; k_vmax = k; } + } + vpath[j] = k_vmax; + hmm->vprob_tmp[j] = vmax * eprob[j]; + vnorm += hmm->vprob_tmp[j]; + } + for (j=0; jvprob_tmp[j] /= vnorm; + double *tmp = hmm->vprob; hmm->vprob = hmm->vprob_tmp; hmm->vprob_tmp = tmp; + + if ( hmm->snapshot && i==hmm->snapshot->isite ) + { + hmm->snapshot->pos = sites[i]; + memcpy(hmm->snapshot->vit_prob, hmm->vprob, sizeof(*hmm->vprob)*nstates); + } + } + + // Find the most likely state + int iptr = 0; + for (i=1; ivprob[iptr] < hmm->vprob[i] ) iptr = i; + + // Trace back the Viterbi path, we are reusing vpath for storing the states (vpath[i*nstates]) + for (i=n-1; i>=0; i--) + { + assert( iptrvpath[i*nstates + iptr]vpath[i*nstates + iptr]; + hmm->vpath[i*nstates] = iptr; // reusing the array for different purpose here + } +} + +void hmm_run_fwd_bwd(hmm_t *hmm, int n, double *eprobs, uint32_t *sites) +{ + // Init arrays when run for the first time + if ( hmm->nfwd < n ) + { + hmm->nfwd = n; + hmm->fwd = (double*) realloc(hmm->fwd, sizeof(double)*(hmm->nfwd+1)*hmm->nstates); + } + if ( !hmm->bwd ) + { + hmm->bwd = (double*) malloc(sizeof(double)*hmm->nstates); + hmm->bwd_tmp = (double*) malloc(sizeof(double)*hmm->nstates); + } + + + // Init all states with equal likelihood + int i,j,k, nstates = hmm->nstates; + memcpy(hmm->fwd, hmm->init.fwd_prob, sizeof(*hmm->init.fwd_prob)*nstates); + memcpy(hmm->bwd, hmm->init.bwd_prob, sizeof(*hmm->init.bwd_prob)*nstates); + + uint32_t prev_pos = hmm->init.isite ? hmm->init.pos : sites[0]; + + // Run fwd + for (i=0; ifwd[i*nstates]; + double *fwd = &hmm->fwd[(i+1)*nstates]; + double *eprob = &eprobs[i*nstates]; + + int pos_diff = sites[i] == prev_pos ? 0 : sites[i] - prev_pos - 1; + + _set_tprob(hmm, pos_diff); + if ( hmm->set_tprob ) hmm->set_tprob(hmm, prev_pos, sites[i], hmm->set_tprob_data, hmm->curr_tprob); + prev_pos = sites[i]; + + double norm = 0; + for (j=0; jcurr_tprob,hmm->nstates,j,k); + fwd[j] = pval * eprob[j]; + norm += fwd[j]; + } + for (j=0; jsnapshot ) + { + i = hmm->snapshot->isite; + hmm->snapshot->pos = sites[i]; + memcpy(hmm->snapshot->fwd_prob, hmm->fwd + (i+1)*nstates, sizeof(*hmm->fwd)*nstates); + } + + // Run bwd + double *bwd = hmm->bwd, *bwd_tmp = hmm->bwd_tmp; + prev_pos = sites[n-1]; + for (i=0; ifwd[(n-i)*nstates]; + double *eprob = &eprobs[(n-i-1)*nstates]; + + int pos_diff = sites[n-i-1] == prev_pos ? 0 : prev_pos - sites[n-i-1] - 1; + + _set_tprob(hmm, pos_diff); + if ( hmm->set_tprob ) hmm->set_tprob(hmm, sites[n-i-1], prev_pos, hmm->set_tprob_data, hmm->curr_tprob); + prev_pos = sites[n-i-1]; + + double bwd_norm = 0; + for (j=0; jcurr_tprob,hmm->nstates,k,j); + bwd_tmp[j] = pval; + bwd_norm += pval; + } + double norm = 0; + for (j=0; jnfwd < n ) + { + hmm->nfwd = n; + hmm->fwd = (double*) realloc(hmm->fwd, sizeof(double)*(hmm->nfwd+1)*hmm->nstates); + } + if ( !hmm->bwd ) + { + hmm->bwd = (double*) malloc(sizeof(double)*hmm->nstates); + hmm->bwd_tmp = (double*) malloc(sizeof(double)*hmm->nstates); + } + + // Init all states with equal likelihood + int i,j,k, nstates = hmm->nstates; + memcpy(hmm->fwd, hmm->init.fwd_prob, sizeof(*hmm->init.fwd_prob)*nstates); + memcpy(hmm->bwd, hmm->init.bwd_prob, sizeof(*hmm->init.bwd_prob)*nstates); + uint32_t prev_pos = hmm->init.isite ? hmm->init.pos : sites[0]; + + // New transition matrix: temporary values + double *tmp_xi = (double*) calloc(nstates*nstates,sizeof(double)); + double *tmp_gamma = (double*) calloc(nstates,sizeof(double)); + double *fwd_bwd = (double*) malloc(sizeof(double)*nstates); + + // Run fwd + for (i=0; ifwd[i*nstates]; + double *fwd = &hmm->fwd[(i+1)*nstates]; + double *eprob = &eprobs[i*nstates]; + + int pos_diff = sites[i] == prev_pos ? 0 : sites[i] - prev_pos - 1; + + _set_tprob(hmm, pos_diff); + if ( hmm->set_tprob ) hmm->set_tprob(hmm, prev_pos, sites[i], hmm->set_tprob_data, hmm->curr_tprob); + prev_pos = sites[i]; + + double norm = 0; + for (j=0; jcurr_tprob,hmm->nstates,j,k); + fwd[j] = pval * eprob[j]; + norm += fwd[j]; + } + for (j=0; jbwd, *bwd_tmp = hmm->bwd_tmp; + prev_pos = sites[n-1]; + for (i=0; ifwd[(n-i)*nstates]; + double *eprob = &eprobs[(n-i-1)*nstates]; + + int pos_diff = sites[n-i-1] == prev_pos ? 0 : prev_pos - sites[n-i-1] - 1; + + _set_tprob(hmm, pos_diff); + if ( hmm->set_tprob ) hmm->set_tprob(hmm, sites[n-i-1], prev_pos, hmm->set_tprob_data, hmm->curr_tprob); + prev_pos = sites[n-i-1]; + + double bwd_norm = 0; + for (j=0; jcurr_tprob,hmm->nstates,k,j); + bwd_tmp[j] = pval; + bwd_norm += pval; + } + double norm = 0; + for (j=0; jtprob_arr,hmm->nstates,k,j)*eprob[k] / norm; + } + } + + for (j=0; jcurr_tprob,nstates,k,j) = MAT(tmp_xi,nstates,k,j) / tmp_gamma[j]; + norm += MAT(hmm->curr_tprob,nstates,k,j); + } + for (k=0; kcurr_tprob,nstates,k,j) /= norm; + } + free(tmp_gamma); + free(tmp_xi); + free(fwd_bwd); + return hmm->curr_tprob; +} + +void hmm_destroy(hmm_t *hmm) +{ + free(hmm->init.vit_prob); + free(hmm->init.fwd_prob); + free(hmm->init.bwd_prob); + free(hmm->vprob); + free(hmm->vprob_tmp); + free(hmm->vpath); + free(hmm->curr_tprob); + free(hmm->tmp); + free(hmm->tprob_arr); + free(hmm->fwd); + free(hmm->bwd); + free(hmm->bwd_tmp); + free(hmm); +} + diff --git a/HMM.h b/HMM.h new file mode 100644 index 0000000..3e5cf7f --- /dev/null +++ b/HMM.h @@ -0,0 +1,133 @@ +/* The MIT License + + Copyright (c) 2014-2015 Genome Research Ltd. + + Author: Petr Danecek + + Permission is hereby granted, free of charge, to any person obtaining a copy + of this software and associated documentation files (the "Software"), to deal + in the Software without restriction, including without limitation the rights + to use, copy, modify, merge, publish, distribute, sublicense, and/or sell + copies of the Software, and to permit persons to whom the Software is + furnished to do so, subject to the following conditions: + + The above copyright notice and this permission notice shall be included in + all copies or substantial portions of the Software. + + THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR + IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, + FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE + AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER + LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, + OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN + THE SOFTWARE. + + */ + +#ifndef __HMM_H__ +#define __HMM_H__ + +#define MAT(matrix,ndim,i,j) (matrix)[(ndim)*(i)+(j)] // P(i|j), that is, transition j->i + +typedef struct _hmm_t hmm_t; + +typedef void (*set_tprob_f) (hmm_t *hmm, uint32_t prev_pos, uint32_t pos, void *data, double *tprob); + +/** + * hmm_init() - initialize HMM + * @nstates: number of states + * @tprob: transition probabilities matrix (nstates x nstates), for elements ordering + * see the MAT macro above. + * @ntprob: number of precalculated tprob matrices or 0 for constant probs, independent + * of distance + */ +hmm_t *hmm_init(int nstates, double *tprob, int ntprob); +void hmm_set_tprob(hmm_t *hmm, double *tprob, int ntprob); + +#define HMM_VIT 1 +#define HMM_FWD 2 +#define HMM_BWD 4 + +/** + * hmm_init_states() - initial state probabilities + * @probs: initial state probabilities or NULL to reset to default + * + * If uncalled, all states are initialized with the same likelihood + */ +void hmm_init_states(hmm_t *hmm, double *probs); + +/** + * hmm_snapshot() - take the model's snapshot, intended for sliding HMM + * @snapshot: NULL or snapshot returned by previous hmm_snapshot() call, must be free()-ed by the caller + * @isite: take the snapshot at i-th step + */ +void *hmm_snapshot(hmm_t *hmm, void *snapshot, int isite); + +/** + * hmm_restore() - restore model's snapshot, intended for sliding HMM + * @snapshot: snapshot returned by hmm_snapshot() call or NULL to reset + * @isite: take the snapshot at i-th step + */ +void hmm_restore(hmm_t *hmm, void *snapshot); + +/** + * hmm_get_tprob() - return the array of transition matrices, precalculated + * to ntprob positions. The first matrix is the initial tprob matrix + * set by hmm_init() or hmm_set_tprob() + */ +double *hmm_get_tprob(hmm_t *hmm); +int hmm_get_nstates(hmm_t *hmm); + +/** + * hmm_set_tprob_func() - custom setter of transition probabilities + */ +void hmm_set_tprob_func(hmm_t *hmm, set_tprob_f set_tprob, void *data); + +/** + * hmm_run_viterbi() - run Viterbi algorithm + * @nsites: number of sites + * @eprob: emission probabilities for each site and state (nsites x nstates) + * @sites: list of positions + * + * When done, hmm->vpath[] contains the calculated Viterbi path. The states + * are indexed starting from 0, a state at i-th site can be accessed as + * vpath[nstates*i]. + */ +void hmm_run_viterbi(hmm_t *hmm, int nsites, double *eprob, uint32_t *sites); + +/** + * hmm_get_viterbi_path() - the viterbi path: state at ith site is the + * (nstates*isite)-th element + */ +uint8_t *hmm_get_viterbi_path(hmm_t *hmm); + +/** + * hmm_run_fwd_bwd() - run the forward-backward algorithm + * @nsites: number of sites + * @eprob: emission probabilities for each site and state (nsites x nstates) + * @sites: list of positions + */ +void hmm_run_fwd_bwd(hmm_t *hmm, int nsites, double *eprob, uint32_t *sites); + +/** + * hmm_get_fwd_bwd_prob() - the probability of i-th state at j-th site can + * be accessed as fwd_bwd[j*nstates+i]. + */ +double *hmm_get_fwd_bwd_prob(hmm_t *hmm); + +/** + * hmm_run_baum_welch() - run one iteration of Baum-Welch algorithm + * @nsites: number of sites + * @eprob: emission probabilities for each site and state (nsites x nstates) + * @sites: list of positions + * + * Same as hmm_run_fwd_bwd, in addition a pointer to a matrix with the new + * transition probabilities is returned. In this verison, emission + * probabilities are not updated. + */ +double *hmm_run_baum_welch(hmm_t *hmm, int nsites, double *eprob, uint32_t *sites); + +void hmm_destroy(hmm_t *hmm); + +#endif + diff --git a/INSTALL b/INSTALL new file mode 100644 index 0000000..df3df00 --- /dev/null +++ b/INSTALL @@ -0,0 +1,67 @@ +System Requirements +=================== + +BCFtools and HTSlib depend on the zlib library , the bzip2 +library and liblzma . Building +them requires development files to be installed on the build machine; +note that some Linux distributions package these separately from the library +itself (see below). + +The bzip2 and liblzma dependencies can be removed if full CRAM support +is not needed - see HTSlib's INSTALL file for details. + +Packages for dpkg-based Linux distributions (Debian / Ubuntu) are: + + zlib1g-dev + libbz2-dev + liblzma-dev + +Packages for rpm or yum-based Linux distributions (RedHat / Fedora / CentOS) +are: + + zlib-devel + bzip2-devel + xz-devel + +Compilation +=========== + +'cd' to the bcftools-1.x directory containing the package's source and type +'make' to compile BCFtools. + +This BCFtools release contains a copy of HTSlib which will be used to build +BCFtools. If you already have a system-installed HTSlib or another HTSlib +that you would prefer to build against, you can arrange this by overriding +$(HTSDIR) by typing 'make HTSDIR=/path/to/htslib-source' -- see the makefile +for details. + + +Optional Compilation with GSL +============================= + +The 'polysomy' command depends on the GNU Scientific Library (GSL) and is not +enabled by default. In order to compile it, type 'make clean && make USE_GPL=1'. + +Note that GSL is distributed under a GPL license, so when USE_GPL=1 is used to +compile bcftools, the resulting program must only be distributed under terms +compatible with that license. + +In the default compilation mode the program is dual licensed and you may +choose to be licensed under the terms of the MIT/Expat license or the +GNU General Public License (GPL). + + +Installation +============ + +Type 'make install' to install the bcftools executable and associated scripts +and a manual page to /usr/local. + +Type 'make prefix=/path/to/dir install' to install everything under your +choice of installation directory. The install target also understands +DESTDIR and the other usual installation directory variables. + +The bgzip and tabix utilities are provided by HTSlib. If you have not also +installed HTSlib separately, you may wish to install these utilities by hand +by copying bcftools-1.x/htslib-1.x/{bgzip,tabix} to the same bin directory +to which you have installed bcftools et al. diff --git a/LICENSE b/LICENSE new file mode 100644 index 0000000..26fbc68 --- /dev/null +++ b/LICENSE @@ -0,0 +1,725 @@ +This software is available to you under a choice of one of two licenses. You +may chose to be licensed under the terms of the MIT/Expat license or the GNU +General Public License (GPL), both included below. 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If your program is a subroutine library, you +may consider it more useful to permit linking proprietary applications with +the library. If this is what you want to do, use the GNU Lesser General +Public License instead of this License. But first, please read +. + + +----------------------------------------------------------------------------- + diff --git a/Makefile b/Makefile new file mode 100644 index 0000000..ddb384f --- /dev/null +++ b/Makefile @@ -0,0 +1,260 @@ +# Makefile for bcftools, utilities for Variant Call Format VCF/BCF files. +# +# Copyright (C) 2012-2017 Genome Research Ltd. +# +# Author: Petr Danecek +# +# Permission is hereby granted, free of charge, to any person obtaining a copy +# of this software and associated documentation files (the "Software"), to deal +# in the Software without restriction, including without limitation the rights +# to use, copy, modify, merge, publish, distribute, sublicense, and/or sell +# copies of the Software, and to permit persons to whom the Software is +# furnished to do so, subject to the following conditions: +# +# The above copyright notice and this permission notice shall be included in +# all copies or substantial portions of the Software. +# +# THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +# IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +# FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL +# THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER +# LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING +# FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER +# DEALINGS IN THE SOFTWARE. + +PROG= bcftools +TEST_PROG= test/test-rbuf test/test-regidx + + +all: $(PROG) $(TEST_PROG) + +# Adjust $(HTSDIR) to point to your top-level htslib directory +HTSDIR = ../htslib +include $(HTSDIR)/htslib.mk +include $(HTSDIR)/htslib_static.mk +HTSLIB = $(HTSDIR)/libhts.a +BGZIP = $(HTSDIR)/bgzip +TABIX = $(HTSDIR)/tabix +HTSLIB_LDFLAGS = $(HTSLIB_static_LDFLAGS) +HTSLIB_LIBS = $(HTSLIB_static_LIBS) + +CC = gcc +CPPFLAGS = +CFLAGS = -g -Wall -Wc++-compat -O2 +LDFLAGS = +LIBS = + +ifeq "$(shell uname -s)" "Darwin" +DYNAMIC_FLAGS = -Wl,-export_dynamic +else +DYNAMIC_FLAGS = -rdynamic +endif + +# TODO Use configure or htslib.pc to add -rdynamic/-ldl conditionally +ALL_CPPFLAGS = -I. $(HTSLIB_CPPFLAGS) $(CPPFLAGS) +ALL_LDFLAGS = $(DYNAMIC_FLAGS) $(HTSLIB_LDFLAGS) $(LDFLAGS) +ALL_LIBS = -lm -lz -ldl $(LIBS) + +OBJS = main.o vcfindex.o tabix.o \ + vcfstats.o vcfisec.o vcfmerge.o vcfquery.o vcffilter.o filter.o vcfsom.o \ + vcfnorm.o vcfgtcheck.o vcfview.o vcfannotate.o vcfroh.o vcfconcat.o \ + vcfcall.o mcall.o vcmp.o gvcf.o reheader.o convert.o vcfconvert.o tsv2vcf.o \ + vcfcnv.o HMM.o vcfplugin.o consensus.o ploidy.o bin.o hclust.o version.o \ + regidx.o smpl_ilist.o csq.o \ + mpileup.o bam2bcf.o bam2bcf_indel.o bam_sample.o \ + ccall.o em.o prob1.o kmin.o # the original samtools calling + +EXTRA_CPPFLAGS = -I. -I$(HTSDIR) -DPLUGINPATH=\"$(pluginpath)\" +GSL_LIBS = + +# The polysomy command is not compiled by default because it brings dependency +# on libgsl. The command can be compiled wth `make USE_GPL=1`. See the INSTALL +# and LICENSE documents to understand license implications. +ifdef USE_GPL + EXTRA_CPPFLAGS += -DUSE_GPL + OBJS += polysomy.o peakfit.o + GSL_LIBS = -lgsl -lcblas +endif + +prefix = /usr/local +exec_prefix = $(prefix) +bindir = $(exec_prefix)/bin +libdir = $(exec_prefix)/lib +libexecdir = $(exec_prefix)/libexec +mandir = $(prefix)/share/man +man1dir = $(mandir)/man1 + +plugindir = $(libexecdir)/bcftools +pluginpath = $(plugindir) + +MKDIR_P = mkdir -p +INSTALL = install -p +INSTALL_PROGRAM = $(INSTALL) +INSTALL_DATA = $(INSTALL) -m 644 +INSTALL_DIR = $(MKDIR_P) -m 755 + +MISC_PROGRAMS = \ + misc/color-chrs.pl \ + misc/guess-ploidy.py \ + misc/plot-vcfstats \ + misc/plot-roh.py \ + misc/run-roh.pl \ + misc/vcfutils.pl + +all:$(PROG) plugins + +# See htslib/Makefile +PACKAGE_VERSION = 1.4.1 +ifneq "$(wildcard .git)" "" +PACKAGE_VERSION := $(shell git describe --always --dirty) +DOC_VERSION := $(shell git describe --always)+ +DOC_DATE := $(shell date +'%Y-%m-%d %R %Z') +version.h: $(if $(wildcard version.h),$(if $(findstring "$(PACKAGE_VERSION)",$(shell cat version.h)),,force)) +endif +version.h: + echo '#define BCFTOOLS_VERSION "$(PACKAGE_VERSION)"' > $@ + + +.SUFFIXES:.c .o +.PHONY:all clean clean-all clean-plugins distclean install lib tags test testclean force plugins docs + +force: + +.c.o: + $(CC) $(CFLAGS) $(EXTRA_CPPFLAGS) $(ALL_CPPFLAGS) -c -o $@ $< + +test: $(PROG) plugins test/test-rbuf test/test-regidx $(BGZIP) $(TABIX) + ./test/test-regidx + ./test/test.pl --exec bgzip=$(BGZIP) --exec tabix=$(TABIX) + +test-plugins: $(PROG) plugins test/test-rbuf $(BGZIP) $(TABIX) + ./test/test.pl --plugins --exec bgzip=$(BGZIP) --exec tabix=$(TABIX) + + +# Plugin rules +PLUGINC = $(foreach dir, plugins, $(wildcard $(dir)/*.c)) +PLUGINS = $(PLUGINC:.c=.so) +PLUGINM = $(PLUGINC:.c=.mk) + +ifeq "$(shell uname -s)" "Darwin" +$(PLUGINS): | bcftools +PLUGIN_FLAGS = -bundle -bundle_loader bcftools +else +PLUGIN_FLAGS = -fPIC -shared +endif + +%.so: %.c version.h version.c + $(CC) $(PLUGIN_FLAGS) $(CFLAGS) $(EXTRA_CPPFLAGS) $(CPPFLAGS) $(LDFLAGS) -o $@ version.c $< $(LIBS) + +-include $(PLUGINM) + +plugins: $(PLUGINS) + + +bcftools_h = bcftools.h $(htslib_hts_defs_h) $(htslib_vcf_h) +bin_h = bin.h $(htslib_hts_h) +call_h = call.h $(htslib_vcf_h) $(htslib_synced_bcf_reader_h) vcmp.h +convert_h = convert.h $(htslib_vcf_h) +tsv2vcf_h = tsv2vcf.h $(htslib_vcf_h) +filter_h = filter.h $(htslib_vcf_h) +ploidy_h = ploidy.h regidx.h +prob1_h = prob1.h $(htslib_vcf_h) $(call_h) +roh_h = HMM.h $(htslib_vcf_h) $(htslib_synced_bcf_reader_h) $(htslib_kstring_h) $(htslib_kseq_h) $(bcftools_h) +cnv_h = HMM.h $(htslib_vcf_h) $(htslib_synced_bcf_reader_h) +bam2bcf_h = bam2bcf.h $(htslib_hts_h) $(htslib_vcf_h) +bam_sample_h = bam_sample.h $(htslib_sam_h) + +main.o: main.c $(htslib_hts_h) version.h $(bcftools_h) +vcfannotate.o: vcfannotate.c $(htslib_vcf_h) $(htslib_synced_bcf_reader_h) $(htslib_kseq_h) $(bcftools_h) vcmp.h $(filter_h) +vcfplugin.o: vcfplugin.c $(htslib_vcf_h) $(htslib_synced_bcf_reader_h) $(htslib_kseq_h) $(bcftools_h) vcmp.h $(filter_h) +vcfcall.o: vcfcall.c $(htslib_vcf_h) $(htslib_kfunc_h) $(htslib_synced_bcf_reader_h) $(htslib_khash_str2int_h) $(bcftools_h) $(call_h) $(prob1_h) $(ploidy_h) +vcfconcat.o: vcfconcat.c $(htslib_vcf_h) $(htslib_synced_bcf_reader_h) $(htslib_kseq_h) $(htslib_bgzf_h) $(htslib_tbx_h) $(bcftools_h) +vcfconvert.o: vcfconvert.c $(htslib_vcf_h) $(htslib_bgzf_h) $(htslib_synced_bcf_reader_h) $(htslib_vcfutils_h) $(bcftools_h) $(filter_h) $(convert_h) $(tsv2vcf_h) +vcffilter.o: vcffilter.c $(htslib_vcf_h) $(htslib_synced_bcf_reader_h) $(htslib_vcfutils_h) $(bcftools_h) $(filter_h) rbuf.h +vcfgtcheck.o: vcfgtcheck.c $(htslib_vcf_h) $(htslib_synced_bcf_reader_h) $(htslib_vcfutils_h) $(bcftools_h) hclust.h +vcfindex.o: vcfindex.c $(htslib_vcf_h) $(htslib_tbx_h) $(htslib_kstring_h) +vcfisec.o: vcfisec.c $(htslib_vcf_h) $(htslib_synced_bcf_reader_h) $(htslib_vcfutils_h) $(bcftools_h) $(filter_h) +vcfmerge.o: vcfmerge.c $(htslib_vcf_h) $(htslib_synced_bcf_reader_h) $(htslib_vcfutils_h) $(htslib_faidx_h) regidx.h $(bcftools_h) vcmp.h $(htslib_khash_h) +vcfnorm.o: vcfnorm.c $(htslib_vcf_h) $(htslib_synced_bcf_reader_h) $(htslib_faidx_h) $(bcftools_h) rbuf.h +vcfquery.o: vcfquery.c $(htslib_vcf_h) $(htslib_synced_bcf_reader_h) $(htslib_vcfutils_h) $(bcftools_h) $(filter_h) $(convert_h) +vcfroh.o: vcfroh.c $(roh_h) +vcfcnv.o: vcfcnv.c $(cnv_h) +vcfsom.o: vcfsom.c $(htslib_vcf_h) $(htslib_synced_bcf_reader_h) $(htslib_vcfutils_h) $(bcftools_h) +vcfstats.o: vcfstats.c $(htslib_vcf_h) $(htslib_synced_bcf_reader_h) $(htslib_vcfutils_h) $(htslib_faidx_h) $(bcftools_h) $(filter_h) $(bin_h) +vcfview.o: vcfview.c $(htslib_vcf_h) $(htslib_synced_bcf_reader_h) $(htslib_vcfutils_h) $(bcftools_h) $(filter_h) +reheader.o: reheader.c $(htslib_vcf_h) $(htslib_bgzf_h) $(htslib_tbx_h) $(htslib_kseq_h) $(bcftools_h) +tabix.o: tabix.c $(htslib_bgzf_h) $(htslib_tbx_h) +ccall.o: ccall.c $(htslib_kfunc_h) $(call_h) kmin.h $(prob1_h) +convert.o: convert.c $(htslib_vcf_h) $(htslib_synced_bcf_reader_h) $(htslib_vcfutils_h) $(bcftools_h) $(convert_h) +tsv2vcf.o: tsv2vcf.c $(tsv2vcf_h) +em.o: em.c $(htslib_vcf_h) kmin.h $(call_h) +filter.o: filter.c $(htslib_khash_str2int_h) $(filter_h) $(bcftools_h) $(htslib_hts_defs_h) $(htslib_vcfutils_h) +gvcf.o: gvcf.c gvcf.h $(call_h) +kmin.o: kmin.c kmin.h +mcall.o: mcall.c $(htslib_kfunc_h) $(call_h) +prob1.o: prob1.c $(prob1_h) +vcmp.o: vcmp.c $(htslib_hts_h) vcmp.h +ploidy.o: ploidy.c regidx.h $(htslib_khash_str2int_h) $(htslib_kseq_h) $(htslib_hts_h) $(bcftools_h) $(ploidy_h) +polysomy.o: polysomy.c $(htslib_vcf_h) $(htslib_synced_bcf_reader_h) $(bcftools_h) peakfit.h +peakfit.o: peakfit.c peakfit.h $(htslib_hts_h) $(htslib_kstring_h) +bin.o: bin.c $(bin_h) +regidx.o: regidx.c $(htslib_hts_h) $(htslib_kstring_h) $(htslib_kseq_h) $(htslib_khash_str2int_h) regidx.h +consensus.o: consensus.c $(htslib_hts_h) $(htslib_kseq_h) rbuf.h $(bcftools_h) regidx.h +mpileup.o: mpileup.c $(htslib_sam_h) $(htslib_faidx_h) $(htslib_kstring_h) $(htslib_khash_str2int_h) regidx.h $(bcftools_h) $(call_h) $(bam2bcf_h) $(bam_sample_h) +bam_sample.o: $(bam_sample_h) $(htslib_hts_h) $(htslib_khash_str2int_h) +version.o: version.h version.c +hclust.o: hclust.c hclust.h +smpl_ilist.o: smpl_ilist.c smpl_ilist.h +csq.o: csq.c smpl_ilist.h regidx.h filter.h kheap.h rbuf.h + +test/test-rbuf.o: test/test-rbuf.c rbuf.h + +test/test-rbuf: test/test-rbuf.o + $(CC) $(LDFLAGS) -o $@ $^ $(ALL_LIBS) + +test/test-regidx.o: test/test-regidx.c regidx.h + +test/test-regidx: test/test-regidx.o regidx.o $(HTSLIB) + $(CC) $(ALL_LDFLAGS) -o $@ $^ $(HTSLIB) -lpthread $(HTSLIB_LIBS) $(ALL_LIBS) + +bcftools: $(HTSLIB) $(OBJS) + $(CC) $(ALL_LDFLAGS) -o $@ $(OBJS) $(HTSLIB) -lpthread $(HTSLIB_LIBS) $(GSL_LIBS) $(ALL_LIBS) + +doc/bcftools.1: doc/bcftools.txt + cd doc && a2x -adate="$(DOC_DATE)" -aversion=$(DOC_VERSION) --doctype manpage --format manpage bcftools.txt + +doc/bcftools.html: doc/bcftools.txt + cd doc && a2x -adate="$(DOC_DATE)" -aversion=$(DOC_VERSION) --doctype manpage --format xhtml bcftools.txt + +# make docs target depends the a2x asciidoc program +docs: doc/bcftools.1 doc/bcftools.html + +# To avoid an install dependency on asciidoc, the make install target +# does not depend on doc/bcftools.1 +# bcftools.1 is a generated file from the asciidoc bcftools.txt file. +# Since there is no make dependency, bcftools.1 can be out-of-date and +# make docs can be run to update if asciidoc is available +install: $(PROG) $(PLUGINS) + $(INSTALL_DIR) $(DESTDIR)$(bindir) $(DESTDIR)$(man1dir) $(DESTDIR)$(plugindir) + $(INSTALL_PROGRAM) $(PROG) $(MISC_PROGRAMS) $(DESTDIR)$(bindir) + $(INSTALL_DATA) doc/bcftools.1 $(DESTDIR)$(man1dir) + $(INSTALL_PROGRAM) plugins/*.so $(DESTDIR)$(plugindir) + +clean: testclean clean-plugins + -rm -f gmon.out *.o *~ $(PROG) version.h plugins/*.so plugins/*.P + -rm -rf *.dSYM plugins/*.dSYM test/*.dSYM + +clean-plugins: + -rm -f plugins/*.so plugins/*.P + -rm -rf plugins/*.dSYM + +testclean: + -rm -f test/*.o test/*~ $(TEST_PROG) + +distclean: clean + -rm -f TAGS + +clean-all: clean clean-htslib + +tags: + ctags -f TAGS *.[ch] plugins/*.[ch] diff --git a/NEWS b/NEWS new file mode 100644 index 0000000..42b86fd --- /dev/null +++ b/NEWS @@ -0,0 +1,236 @@ +## Noteworthy changes for the next release: + +## Release 1.4.1 (8 May 2017) + +* `roh`: Fixed malfunctioning options `-m, --genetic-map` and `-M, --rec-rate`, + and newly allowed their combination. Added a convenience wrapper `misc/run-roh.pl` + and an interactive script for visualizing the calls `misc/plot-roh.py`. + +* `csq`: More control over warning messages (#585). + +* Portability improvements (#587). Still work to be done on this front. + +* Add support for breakends to `view`, `norm`, `query` and filtering (#592). + +* `plot-vcfstats`: Fix for python 2/3 compatibility (#593). + +* New `-l, --list` option for `+af-dist` plugin. + +* New `-i, --use-id` option for `+fix-ref` plugin. + +* Add `--include/--exclude` options to `+guess-ploidy` plugin. + +* New `+check-sparsity` plugin. + +* Miscellaneous bugfixes for #575, #584, #588, #599, #535. + + +## Release 1.4 (13 March 2017) + +Two new commands - `mpileup` and `csq`: + +* The `mpileup` command has been imported from samtools to bcftools. The + reasoning behind this is that bcftools calling is intimately tied to mpileup + and any changes to one, often requires changes to the other. Only the + genotype likelihood (BCF output) part of mpileup has moved to bcftools, + while the textual pileup output remains in samtools. The BCF output option + in `samtools mpileup` will likely be removed in a release or two or when + changes to `bcftools call` are incompatible with the old mpileup output. + + The basic mpileup functionality remains unchanged as do most of the command + line options, but there are some differences and new features that one + should be aware of: + + - The option `samtools mpileup -t, --output-tags` changed to `bcftools + mpileup -a, --annotate` to avoid conflict with the `-t, --targets` + option common across other bcftools commands. + + - `-O, --output-BP` and `-s, --output-MQ` are no longer used as they are + only for textual pipelup output, which is not included in `bcftools + mpileup`. `-O` short option reassigned to `--output-type` and `-s` + reassigned to `--samples` for consistency with other bcftools commands. + + - `-g, --BCF`, `-v, --VCF`, and ` -u, --uncompressed` options from + `samtools mpileup` are no longer used, being replaced by the + `-O, --output-type` option common to other bcftools commands. + + - The `-f, --fasta-ref` option is now required by default to help avoid user + errors. Can be diabled using `--no-reference`. + + - The option `-d, --depth .. max per-file depth` now behaves as expected + and according to the documentation, and prints a meaningful diagnostics. + + - The `-S, --samples-file` can be used to rename samples on the fly. See man + page for details. + + - The `-G, --read-groups` functionality has been extended to allow + reassignment, grouping and exclusion of readgroups. See man page for + details. + + - The `-l, --positions` replaced by the `-t, --targets` and + `-T, --targets-file` options to be consistent with other bcftools + commands. + + - gVCF output is supported. Per-sample gVCFs created by mpileup can be + merged using `bcftools merge --gvcf`. + + - Can generate mpileup output on multiple (indexed) regions using the + `-r, --regions` and `-R, --regions-file` options. In samtools, one + was restricted to a single region with the `-r, --region` option. + + - Several speedups thanks to @jkbonfield (cf3a55a). + +* `csq`: New command for haplotype-aware variant consequence calling. + See man page and [paper](https://www.ncbi.nlm.nih.gov/pubmed/28205675). + + +Updates, improvements and bugfixes for many other commands: + +* `annotate`: `--collapse` option added. `--mark-sites` now works with + VCF files rather than just tab-delimited files. Now possible to annotate + a subset of samples from tab file, not just VCF file (#469). Bugfixes (#428). + +* `call`: New option `-F, --prior-freqs` to take advantage of prior knowledge + of population allele frequencies. Improved calculation of the QUAL score + particularly for REF sites (#449, 7c56870). `PLs>=256` allowed in + `call -m`. Bugfixes (#436). + +* `concat --naive` now works with vcf.gz in addition to bcf files. + +* `consensus`: handle variants overlapping region boundaries (#400). + +* `convert`: gvcf2vcf support for mpileup and GATK. new `--sex` option to + assign sex to be used in certain output types (#500). Large speedup of + `--hapsample` and `--haplegendsample` (e8e369b) especially with `--threads` + option enabled. Bugfixes (#460). + +* `cnv`: improvements to output (be8b378). + +* `filter`: bugfixes (#406). + +* `gtcheck`: improved cross-check mode (#441). + +* `index` can now specify the path to the output index file. Also, gains the + `--threads` option. + +* `merge`: Large overhaul of `merge` command including support for merging + gVCF files created by `bcftools mpileup --gvcf` with the new `-g, --gvcf` + option. New options `-F` to control filter logic and `-0` to set missing + data to REF. Resolved a number of longstanding issues (#296, #361, #401, + #408, #412). + +* `norm`: Bugfixes (#385,#452,#439), more informative error messages (#364). + +* `query`: `%END` plus `%POS0`, `%END0` (0-indexed) support - allows easy BED + format output (#479). `%TBCSQ` for use with the new `csq` command. Bugfixes + (#488,#489). + +* `plugin`: A number of new plugins: + + - `GTsubset` (thanks to @dlaehnemann) + - `ad-bias` + - `af-dist` + - `fill-from-fasta` + - `fixref` + - `guess-ploidy` (deprecates `vcf2sex` plugin) + - `isecGT` + - `trio-switch-rate` + + and changes to existing plugins: + + - `tag2tag`: Added `gp-to-gt`, `pl-to-gl` and `--threshold` options and + bugfixes (#475). + - `ad-bias`: New `-d` option for minimum depth. + - `impute-info`: Bugfix (49a9eaf). + - `fill-tags`: Added ability to aggregate tags for sample subgroups, thanks + to @mh11. (#503). HWE tag added as an option. + - `mendelian`: Bugfix (#566). + +* `reheader`: allow muiltispace delimiters in `--samples` option. + +* `roh`: Now possible to process multiple samples at once. This allows + considerable speedups for files with thousands of samples where the cost of + HMM is neglibible compared to I/O and decompressing. In order to fit tens of + thousands samples in memory, a sliding HMM can be used (new `--buffer-size` + option). Viterbi training now uses Baum-Welch algorithm, and works much + better. Support for gVCFs or FORMAT/PL tags. Added `-o, output` and + `-O, --output-type` options to control output of sites or regions + (compression optional). Many bugs fixed - do not segfault on missing PL + values anymore, a typo in genetic map calculation resulted in a slowdown and + incorrect results. + +* `stats`: Bugfixes (16414e6), new options `-af-bins` and `-af-tags` to control + allele frequency binning of output. Per-sample genotype concordance tables + added (#477). + +* `view -a, --trim-alt-alleles` various bugfixes for missing data and more + informative errors should now be given on failure to pinpoint problems. + + +General changes: + +* Timestamps are now added to header lines summarising the command (#467). + +* Use of the `--threads` options should be faster across the board thanks to + changes in HTSlib meaning meaning threads are now shared by the compression + and decompression calls. + +* Changes to genotype filtering with `-i, --include` and `-e, --exclude` (#454). + + +## Noteworthy changes in release 1.3.1 (22 April 2016) + +* The `concat` command has a new `--naive` option for faster operations on + large BCFs (PR #359). +* `GTisec`: new plugin courtesy of David Laehnemann (@dlaehnemann) to count + genotype intersections across all possible sample subsets in a VCF file. +* Numerous VCF parsing fixes. +* Build fix: _peakfit.c_ now builds correctly with GSL v2 (#378). +* Various bug fixes and improvements to the `annotate` (#365), `call` (#366), + `index` (#367), `norm` (#368, #385), `reheader` (#356), and `roh` (#328) + commands, and to the `fill-tags` (#345) and `tag2tag` (#394) plugins. +* Clarified documentation of `view` filter options, and of the + `--regions-file` and `--targets-file` options (#357, #411). + + +## Noteworthy changes in release 1.3 (15 December 2016) + +* `bcftools call` has new options `--ploidy` and `--ploidy-file` to make + handling sample ploidy easier. See man page for details. +* `stats`: `-i`/`-e` short options changed to `-I`/`-E` to be consistent with + the filtering `-i`/`-e` (`--include`/`--exclude`) options used in other + tools. +* general `--threads` option to control the number of output compression + threads used when outputting compressed VCF or BCF. +* `cnv` and `polysomy`: new commands for detecting CNVs, aneuploidy, and + contamination from SNP genotyping data. +* various new options, plugins, and bug fixes, including #84, #201, #204, + #205, #208, #211, #222, #225, #242, #243, #249, #282, #285, #289, #302, + #311, #318, #336, and #338. + + +## Noteworthy changes in release 1.2 (2 February 2016) + +* new `bcftools consensus` command +* new `bcftools annotate` plugins: fixploidy, vcf2sex, tag2tag +* more features in `bcftools convert` command, amongst others new + `--hapsample` function (thanks to Warren Kretzschmar @wkretzsch) +* support for complements in `bcftools annotate --remove` +* support for `-i`/`-e` filtering expressions in `bcftools isec` +* improved error reporting +* `bcftools call` + - the default prior increased from `-P 1e-3` to `-P 1.1e-3`, some clear + calls were missed with default settings previously + - support for the new symbolic allele `<*>` + - support for `-f GQ` + - bug fixes, such as: proper trimming of DPR tag with `-c`; the `-A` switch + does not add back records removed by `-v` and the behaviour has been made + consistent with `-c` and `-m` +* many bug fixes and improvements, such as + - bug in filtering, FMT & INFO vs INFO & FMT + - fixes in `bcftools merge` + - filter update AN/AC with `-S` + - isec outputs matching records for both VCFs in the Venn mode + - annotate considers alleles when working with `Number=A,R` tags + - new `--set-id` feature for annotate + - `convert` can be used similarly to `view` diff --git a/README b/README new file mode 100644 index 0000000..5cb1bbd --- /dev/null +++ b/README @@ -0,0 +1,5 @@ +BCFtools implements utilities for variant calling (in conjunction with +SAMtools) and manipulating VCF and BCF files. The program is intended +to replace the Perl-based tools from vcftools. + +See INSTALL for building and installation instructions. diff --git a/bam2bcf.c b/bam2bcf.c new file mode 100644 index 0000000..b4fb7f1 --- /dev/null +++ b/bam2bcf.c @@ -0,0 +1,857 @@ +/* bam2bcf.c -- variant calling. + + Copyright (C) 2010-2012 Broad Institute. + Copyright (C) 2012-2014 Genome Research Ltd. + + Author: Heng Li + +Permission is hereby granted, free of charge, to any person obtaining a copy +of this software and associated documentation files (the "Software"), to deal +in the Software without restriction, including without limitation the rights +to use, copy, modify, merge, publish, distribute, sublicense, and/or sell +copies of the Software, and to permit persons to whom the Software is +furnished to do so, subject to the following conditions: + +The above copyright notice and this permission notice shall be included in +all copies or substantial portions of the Software. + +THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL +THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER +LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING +FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER +DEALINGS IN THE SOFTWARE. */ + +#include +#include +#include +#include +#include +#include +#include +#include +#include "bam2bcf.h" + +extern void ks_introsort_uint32_t(size_t n, uint32_t a[]); + +#define CALL_DEFTHETA 0.83 +#define DEF_MAPQ 20 + +#define CAP_DIST 25 + +bcf_callaux_t *bcf_call_init(double theta, int min_baseQ) +{ + bcf_callaux_t *bca; + if (theta <= 0.) theta = CALL_DEFTHETA; + bca = (bcf_callaux_t*) calloc(1, sizeof(bcf_callaux_t)); + bca->capQ = 60; + bca->openQ = 40; bca->extQ = 20; bca->tandemQ = 100; + bca->min_baseQ = min_baseQ; + bca->e = errmod_init(1. - theta); + bca->min_frac = 0.002; + bca->min_support = 1; + bca->per_sample_flt = 0; + bca->npos = 100; + bca->ref_pos = (int*) malloc(bca->npos*sizeof(int)); + bca->alt_pos = (int*) malloc(bca->npos*sizeof(int)); + bca->nqual = 60; + bca->ref_mq = (int*) malloc(bca->nqual*sizeof(int)); + bca->alt_mq = (int*) malloc(bca->nqual*sizeof(int)); + bca->ref_bq = (int*) malloc(bca->nqual*sizeof(int)); + bca->alt_bq = (int*) malloc(bca->nqual*sizeof(int)); + bca->fwd_mqs = (int*) malloc(bca->nqual*sizeof(int)); + bca->rev_mqs = (int*) malloc(bca->nqual*sizeof(int)); + return bca; +} + +void bcf_call_destroy(bcf_callaux_t *bca) +{ + if (bca == 0) return; + errmod_destroy(bca->e); + if (bca->npos) { free(bca->ref_pos); free(bca->alt_pos); bca->npos = 0; } + free(bca->ref_mq); free(bca->alt_mq); free(bca->ref_bq); free(bca->alt_bq); + free(bca->fwd_mqs); free(bca->rev_mqs); + bca->nqual = 0; + free(bca->bases); free(bca->inscns); free(bca); +} + +// position in the sequence with respect to the aligned part of the read +static int get_position(const bam_pileup1_t *p, int *len) +{ + int icig, n_tot_bases = 0, iread = 0, edist = p->qpos + 1; + for (icig=0; icigb->core.n_cigar; icig++) + { + int cig = bam_get_cigar(p->b)[icig] & BAM_CIGAR_MASK; + int ncig = bam_get_cigar(p->b)[icig] >> BAM_CIGAR_SHIFT; + if ( cig==BAM_CMATCH || cig==BAM_CEQUAL || cig==BAM_CDIFF ) + { + n_tot_bases += ncig; + iread += ncig; + continue; + } + if ( cig==BAM_CINS ) + { + n_tot_bases += ncig; + iread += ncig; + continue; + } + if ( cig==BAM_CSOFT_CLIP ) + { + iread += ncig; + if ( iread<=p->qpos ) edist -= ncig; + continue; + } + if ( cig==BAM_CDEL ) continue; + if ( cig==BAM_CHARD_CLIP ) continue; + if ( cig==BAM_CPAD ) continue; + if ( cig==BAM_CREF_SKIP ) continue; + fprintf(stderr,"todo: cigar %d\n", cig); + assert(0); + } + *len = n_tot_bases; + return edist; +} + +void bcf_callaux_clean(bcf_callaux_t *bca, bcf_call_t *call) +{ + memset(bca->ref_pos,0,sizeof(int)*bca->npos); + memset(bca->alt_pos,0,sizeof(int)*bca->npos); + memset(bca->ref_mq,0,sizeof(int)*bca->nqual); + memset(bca->alt_mq,0,sizeof(int)*bca->nqual); + memset(bca->ref_bq,0,sizeof(int)*bca->nqual); + memset(bca->alt_bq,0,sizeof(int)*bca->nqual); + memset(bca->fwd_mqs,0,sizeof(int)*bca->nqual); + memset(bca->rev_mqs,0,sizeof(int)*bca->nqual); + if ( call->ADF ) memset(call->ADF,0,sizeof(int32_t)*(call->n+1)*B2B_MAX_ALLELES); + if ( call->ADR ) memset(call->ADR,0,sizeof(int32_t)*(call->n+1)*B2B_MAX_ALLELES); +} + +/* + Notes: + - Called from bam_plcmd.c by mpileup. Amongst other things, sets the bcf_callret1_t.qsum frequencies + which are carried over via bcf_call_combine and bcf_call2bcf to the output BCF as the QS annotation. + Later it's used for multiallelic calling by bcftools -m + - ref_base is the 4-bit representation of the reference base. It is negative if we are looking at an indel. + */ +/* + * This function is called once for each sample. + * _n is number of pilesups pl contributing reads to this sample + * pl is pointer to array of _n pileups (one pileup per read) + * ref_base is the 4-bit representation of the reference base. It is negative if we are looking at an indel. + * bca is the settings to perform calls across all samples + * r is the returned value of the call + */ +int bcf_call_glfgen(int _n, const bam_pileup1_t *pl, int ref_base, bcf_callaux_t *bca, bcf_callret1_t *r) +{ + int i, n, ref4, is_indel, ori_depth = 0; + + // clean from previous run + r->ori_depth = 0; + r->mq0 = 0; + memset(r->qsum,0,sizeof(float)*4); + memset(r->anno,0,sizeof(double)*16); + memset(r->p,0,sizeof(float)*25); + + if (ref_base >= 0) { + ref4 = seq_nt16_int[ref_base]; + is_indel = 0; + } else ref4 = 4, is_indel = 1; + if (_n == 0) return -1; + // enlarge the bases array if necessary + if (bca->max_bases < _n) { + bca->max_bases = _n; + kroundup32(bca->max_bases); + bca->bases = (uint16_t*)realloc(bca->bases, 2 * bca->max_bases); + } + // fill the bases array + for (i = n = 0; i < _n; ++i) { + const bam_pileup1_t *p = pl + i; + int q, b, mapQ, baseQ, is_diff, min_dist, seqQ; + // set base + if (p->is_del || p->is_refskip || (p->b->core.flag&BAM_FUNMAP)) continue; + ++ori_depth; + mapQ = p->b->core.qual < 255? p->b->core.qual : DEF_MAPQ; // special case for mapQ==255 + if ( !mapQ ) r->mq0++; + baseQ = q = is_indel? p->aux&0xff : (int)bam_get_qual(p->b)[p->qpos]; // base/indel quality + seqQ = is_indel? (p->aux>>8&0xff) : 99; + if (q < bca->min_baseQ) continue; + if (q > seqQ) q = seqQ; + mapQ = mapQ < bca->capQ? mapQ : bca->capQ; + if (q > mapQ) q = mapQ; + if (q > 63) q = 63; + if (q < 4) q = 4; // MQ=0 reads count as BQ=4 + if (!is_indel) { + b = bam_seqi(bam_get_seq(p->b), p->qpos); // base + b = seq_nt16_int[b? b : ref_base]; // b is the 2-bit base + is_diff = (ref4 < 4 && b == ref4)? 0 : 1; + } else { + b = p->aux>>16&0x3f; + is_diff = (b != 0); + } + bca->bases[n++] = q<<5 | (int)bam_is_rev(p->b)<<4 | b; + // collect annotations + if (b < 4) + { + r->qsum[b] += q; + if ( r->ADF ) + { + if ( bam_is_rev(p->b) ) + r->ADR[b]++; + else + r->ADF[b]++; + } + } + ++r->anno[0<<2|is_diff<<1|bam_is_rev(p->b)]; + min_dist = p->b->core.l_qseq - 1 - p->qpos; + if (min_dist > p->qpos) min_dist = p->qpos; + if (min_dist > CAP_DIST) min_dist = CAP_DIST; + r->anno[1<<2|is_diff<<1|0] += baseQ; + r->anno[1<<2|is_diff<<1|1] += baseQ * baseQ; + r->anno[2<<2|is_diff<<1|0] += mapQ; + r->anno[2<<2|is_diff<<1|1] += mapQ * mapQ; + r->anno[3<<2|is_diff<<1|0] += min_dist; + r->anno[3<<2|is_diff<<1|1] += min_dist * min_dist; + + // collect for bias tests + if ( baseQ > 59 ) baseQ = 59; + if ( mapQ > 59 ) mapQ = 59; + int len, pos = get_position(p, &len); + int epos = (double)pos/(len+1) * bca->npos; + int ibq = baseQ/60. * bca->nqual; + int imq = mapQ/60. * bca->nqual; + if ( bam_is_rev(p->b) ) bca->rev_mqs[imq]++; + else bca->fwd_mqs[imq]++; + if ( bam_seqi(bam_get_seq(p->b),p->qpos) == ref_base ) + { + bca->ref_pos[epos]++; + bca->ref_bq[ibq]++; + bca->ref_mq[imq]++; + } + else + { + bca->alt_pos[epos]++; + bca->alt_bq[ibq]++; + bca->alt_mq[imq]++; + } + } + r->ori_depth = ori_depth; + // glfgen + errmod_cal(bca->e, n, 5, bca->bases, r->p); // calculate PL of each genotype + return n; +} + + +/* + * calc_vdb() - returns value between zero (most biased) and one (no bias) + * on success, or HUGE_VAL when VDB cannot be calculated because + * of insufficient depth (<2x) + * + * Variant Distance Bias tests if the variant bases are positioned within the + * reads with sufficient randomness. Unlike other tests, it looks only at + * variant reads and therefore gives different kind of information than Read + * Position Bias for instance. VDB was developed for detecting artefacts in + * RNA-seq calls where reads from spliced transcripts span splice site + * boundaries. The current implementation differs somewhat from the original + * version described in supplementary material of PMID:22524474, but the idea + * remains the same. (Here the random variable tested is the average distance + * from the averaged position, not the average pairwise distance.) + * + * For coverage of 2x, the calculation is exact but is approximated for the + * rest. The result is most accurate between 4-200x. For 3x or >200x, the + * reported values are slightly more favourable than those of a true random + * distribution. + */ +double calc_vdb(int *pos, int npos) +{ + // Note well: the parameters were obtained by fitting to simulated data of + // 100bp reads. This assumes rescaling to 100bp in bcf_call_glfgen(). + const int readlen = 100; + assert( npos==readlen ); + + #define nparam 15 + const float param[nparam][3] = { {3,0.079,18}, {4,0.09,19.8}, {5,0.1,20.5}, {6,0.11,21.5}, + {7,0.125,21.6}, {8,0.135,22}, {9,0.14,22.2}, {10,0.153,22.3}, {15,0.19,22.8}, + {20,0.22,23.2}, {30,0.26,23.4}, {40,0.29,23.5}, {50,0.35,23.65}, {100,0.5,23.7}, + {200,0.7,23.7} }; + + int i, dp = 0; + float mean_pos = 0, mean_diff = 0; + for (i=0; i=200 ) + i = nparam; // shortcut for big depths + else + { + for (i=0; i=dp ) break; + } + float pshift, pscale; + if ( i==nparam ) + { + // the depth is too high, go with 200x + pscale = param[nparam-1][1]; + pshift = param[nparam-1][2]; + } + else if ( i>0 && param[i][0]!=dp ) + { + // linear interpolation of parameters + pscale = (param[i-1][1] + param[i][1])*0.5; + pshift = (param[i-1][2] + param[i][2])*0.5; + } + else + { + pscale = param[i][1]; + pshift = param[i][2]; + } + return 0.5*kf_erfc(-(mean_diff-pshift)*pscale); +} + +double calc_chisq_bias(int *a, int *b, int n) +{ + int na = 0, nb = 0, i, ndf = n; + for (i=0; i= 2 && m >= 2); + + return (n < 8 && m < 8 && U < 50) + ? mw[n-2][m-2][U] + : mann_whitney_1947_(n,m,U); +} + +double mann_whitney_1947_cdf(int n, int m, int U) +{ + int i; + double sum = 0; + for (i=0; i<=U; i++) + sum += mann_whitney_1947(n,m,i); + return sum; +} + +double calc_mwu_bias_cdf(int *a, int *b, int n) +{ + int na = 0, nb = 0, i; + double U = 0, ties = 0; + for (i=0; i=8 && nb>=8 and reasonable if na<8 or nb<8 + if ( na>=8 || nb>=8 ) + { + double mean = ((double)na*nb)*0.5; + // Correction for ties: + // double N = na+nb; + // double var2 = (N*N-1)*N-ties; + // if ( var2==0 ) return 1.0; + // var2 *= ((double)na*nb)/N/(N-1)/12.0; + // No correction for ties: + double var2 = ((double)na*nb)*(na+nb+1)/12.0; + double z = (U_min - mean)/sqrt(2*var2); // z is N(0,1) + return 2.0 - kf_erfc(z); // which is 1 + erf(z) + } + + // Exact calculation + double pval = 2*mann_whitney_1947_cdf(na,nb,U_min); + return pval>1 ? 1 : pval; +} + +double calc_mwu_bias(int *a, int *b, int n) +{ + int na = 0, nb = 0, i; + double U = 0, ties = 0; + for (i=0; imean ? (2.0*mean-U)/mean : U/mean; + } + // Correction for ties: + // double N = na+nb; + // double var2 = (N*N-1)*N-ties; + // if ( var2==0 ) return 1.0; + // var2 *= ((double)na*nb)/N/(N-1)/12.0; + // No correction for ties: + double var2 = ((double)na*nb)*(na+nb+1)/12.0; + if ( na>=8 || nb>=8 ) + { + // Normal approximation, very good for na>=8 && nb>=8 and reasonable if na<8 or nb<8 + return exp(-0.5*(U-mean)*(U-mean)/var2); + } + + // Exact calculation + return mann_whitney_1947(na,nb,U) * sqrt(2*M_PI*var2); +} + +static inline double logsumexp2(double a, double b) +{ + if ( a>b ) + return log(1 + exp(b-a)) + a; + else + return log(1 + exp(a-b)) + b; +} + +void calc_SegBias(const bcf_callret1_t *bcr, bcf_call_t *call) +{ + call->seg_bias = HUGE_VAL; + if ( !bcr ) return; + + int nr = call->anno[2] + call->anno[3]; // number of observed non-reference reads + if ( !nr ) return; + + int avg_dp = (call->anno[0] + call->anno[1] + nr) / call->n; // average depth + double M = floor((double)nr / avg_dp + 0.5); // an approximate number of variants samples in the population + if ( M>call->n ) M = call->n; // clamp M at the number of samples + else if ( M==0 ) M = 1; + double f = M / 2. / call->n; // allele frequency + double p = (double) nr / call->n; // number of variant reads per sample expected if variant not real (poisson) + double q = (double) nr / M; // number of variant reads per sample expected if variant is real (poisson) + double sum = 0; + const double log2 = log(2.0); + + // fprintf(stderr,"M=%.1f p=%e q=%e f=%f dp=%d\n",M,p,q,f,avg_dp); + int i; + for (i=0; in; i++) + { + int oi = bcr[i].anno[2] + bcr[i].anno[3]; // observed number of non-ref reads + double tmp; + if ( oi ) + { + // tmp = log(f) + oi*log(q/p) - q + log(2*(1-f) + f*pow(2,oi)*exp(-q)) + p; // this can under/overflow + tmp = logsumexp2(log(2*(1-f)), log(f) + oi*log2 - q); + tmp += log(f) + oi*log(q/p) - q + p; + } + else + tmp = log(2*f*(1-f)*exp(-q) + f*f*exp(-2*q) + (1-f)*(1-f)) + p; + sum += tmp; + // fprintf(stderr,"oi=%d %e\n", oi,tmp); + } + call->seg_bias = sum; +} + +/** + * bcf_call_combine() - sets the PL array and VDB, RPB annotations, finds the top two alleles + * @n: number of samples + * @calls: each sample's calls + * @bca: auxiliary data structure for holding temporary values + * @ref_base: the reference base + * @call: filled with the annotations + * + * Combines calls across the various samples being studied + * 1. For each allele at each base across all samples the quality is summed so + * you end up with a set of quality sums for each allele present 2. The quality + * sums are sorted. + * 3. Using the sorted quality sums we now create the allele ordering array + * A\subN. This is done by doing the following: + * a) If the reference allele is known it always comes first, otherwise N + * comes first. + * b) Then the rest of the alleles are output in descending order of quality + * sum (which we already know the qsum array was sorted). Any allelles with + * qsum 0 will be excluded. + * 4. Using the allele ordering array we create the genotype ordering array. + * In the worst case with an unknown reference this will be: A0/A0 A1/A0 A1/A1 + * A2/A0 A2/A1 A2/A2 A3/A0 A3/A1 A3/A2 A3/A3 A4/A0 A4/A1 A4/A2 A4/A3 A4/A4 + * 5. The genotype ordering array is then used to extract data from the error + * model 5*5 matrix and is used to produce a Phread likelihood array for each + * sample. + */ +int bcf_call_combine(int n, const bcf_callret1_t *calls, bcf_callaux_t *bca, int ref_base /*4-bit*/, bcf_call_t *call) +{ + int ref4, i, j; + float qsum[5] = {0,0,0,0,0}; + if (ref_base >= 0) { + call->ori_ref = ref4 = seq_nt16_int[ref_base]; + if (ref4 > 4) ref4 = 4; + } else call->ori_ref = -1, ref4 = 0; + + // calculate qsum, this is done by summing normalized qsum across all samples, + // to account for differences in coverage + for (i = 0; i < n; ++i) + { + float sum = 0; + for (j = 0; j < 4; ++j) sum += calls[i].qsum[j]; + if ( sum ) + for (j = 0; j < 4; j++) qsum[j] += calls[i].qsum[j] / sum; + } + + // sort qsum in ascending order (insertion sort) + float *ptr[5], *tmp; + for (i=0; i<5; i++) ptr[i] = &qsum[i]; + for (i=1; i<4; i++) + for (j=i; j>0 && *ptr[j] < *ptr[j-1]; j--) + tmp = ptr[j], ptr[j] = ptr[j-1], ptr[j-1] = tmp; + + // Set the reference allele and alternative allele(s) + for (i=0; i<5; i++) call->a[i] = -1; + for (i=0; i<5; i++) call->qsum[i] = 0; + call->unseen = -1; + call->a[0] = ref4; + for (i=3, j=1; i>=0; i--) // i: alleles sorted by QS; j, a[j]: output allele ordering + { + int ipos = ptr[i] - qsum; // position in sorted qsum array + if ( ipos==ref4 ) + call->qsum[0] = qsum[ipos]; // REF's qsum + else + { + if ( !qsum[ipos] ) break; // qsum is 0, this and consequent alleles are not seen in the pileup + call->qsum[j] = qsum[ipos]; + call->a[j++] = ipos; + } + } + if (ref_base >= 0) + { + // for SNPs, find the "unseen" base + if (((ref4 < 4 && j < 4) || (ref4 == 4 && j < 5)) && i >= 0) + call->unseen = j, call->a[j++] = ptr[i] - qsum; + call->n_alleles = j; + } + else + { + call->n_alleles = j; + if (call->n_alleles == 1) return -1; // no reliable supporting read. stop doing anything + } + /* + * Set the phread likelihood array (call->PL) This array is 15 entries long + * for each sample because that is size of an upper or lower triangle of a + * worst case 5x5 matrix of possible genotypes. This worst case matrix will + * occur when all 4 possible alleles are present and the reference allele + * is unknown. The sides of the matrix will correspond to the reference + * allele (if known) followed by the alleles present in descending order of + * quality sum + */ + { + int x, g[15], z; + double sum_min = 0.; + x = call->n_alleles * (call->n_alleles + 1) / 2; + // get the possible genotypes + // this is done by creating an ordered list of locations g for call (allele a, allele b) in the genotype likelihood matrix + for (i = z = 0; i < call->n_alleles; ++i) { + for (j = 0; j <= i; ++j) { + g[z++] = call->a[j] * 5 + call->a[i]; + } + } + // for each sample calculate the PL + for (i = 0; i < n; ++i) + { + int32_t *PL = call->PL + x * i; + const bcf_callret1_t *r = calls + i; + float min = FLT_MAX; + for (j = 0; j < x; ++j) { + if (min > r->p[g[j]]) min = r->p[g[j]]; + } + sum_min += min; + for (j = 0; j < x; ++j) { + int y; + y = (int)(r->p[g[j]] - min + .499); + if (y > 255) y = 255; + PL[j] = y; + } + } + if ( call->DP4 ) + { + for (i=0; iDP4[4*i] = calls[i].anno[0]; + call->DP4[4*i+1] = calls[i].anno[1]; + call->DP4[4*i+2] = calls[i].anno[2]; + call->DP4[4*i+3] = calls[i].anno[3]; + } + } + if ( call->ADF ) + { + assert( call->n_alleles<=B2B_MAX_ALLELES ); // this is always true for SNPs and so far for indels as well + + // reorder ADR,ADF to match the allele ordering at this site + int32_t tmp[B2B_MAX_ALLELES]; + int32_t *adr = call->ADR + B2B_MAX_ALLELES, *adr_out = call->ADR + B2B_MAX_ALLELES; + int32_t *adf = call->ADF + B2B_MAX_ALLELES, *adf_out = call->ADF + B2B_MAX_ALLELES; + int32_t *adr_tot = call->ADR; // the first bin stores total counts per site + int32_t *adf_tot = call->ADF; + for (i=0; in_alleles; j++) + { + tmp[j] = adr[ call->a[j] ]; + adr_tot[j] += tmp[j]; + } + for (j=0; jn_alleles; j++) adr_out[j] = tmp[j]; + for (j=0; jn_alleles; j++) + { + tmp[j] = adf[ call->a[j] ]; + adf_tot[j] += tmp[j]; + } + for (j=0; jn_alleles; j++) adf_out[j] = tmp[j]; + adf_out += call->n_alleles; + adr_out += call->n_alleles; + adr += B2B_MAX_ALLELES; + adf += B2B_MAX_ALLELES; + } + } + +// if (ref_base < 0) fprintf(stderr, "%d,%d,%f,%d\n", call->n_alleles, x, sum_min, call->unseen); + call->shift = (int)(sum_min + .499); + } + // combine annotations + memset(call->anno, 0, 16 * sizeof(double)); + call->ori_depth = 0; + call->depth = 0; + call->mq0 = 0; + for (i = 0; i < n; ++i) { + call->depth += calls[i].anno[0] + calls[i].anno[1] + calls[i].anno[2] + calls[i].anno[3]; + call->ori_depth += calls[i].ori_depth; + call->mq0 += calls[i].mq0; + for (j = 0; j < 16; ++j) call->anno[j] += calls[i].anno[j]; + } + + calc_SegBias(calls, call); + + // calc_chisq_bias("XPOS", call->bcf_hdr->id[BCF_DT_CTG][call->tid].key, call->pos, bca->ref_pos, bca->alt_pos, bca->npos); + // calc_chisq_bias("XMQ", call->bcf_hdr->id[BCF_DT_CTG][call->tid].key, call->pos, bca->ref_mq, bca->alt_mq, bca->nqual); + // calc_chisq_bias("XBQ", call->bcf_hdr->id[BCF_DT_CTG][call->tid].key, call->pos, bca->ref_bq, bca->alt_bq, bca->nqual); + + call->mwu_pos = calc_mwu_bias(bca->ref_pos, bca->alt_pos, bca->npos); + call->mwu_mq = calc_mwu_bias(bca->ref_mq, bca->alt_mq, bca->nqual); + call->mwu_bq = calc_mwu_bias(bca->ref_bq, bca->alt_bq, bca->nqual); + call->mwu_mqs = calc_mwu_bias(bca->fwd_mqs, bca->rev_mqs, bca->nqual); + +#if CDF_MWU_TESTS + call->mwu_pos_cdf = calc_mwu_bias_cdf(bca->ref_pos, bca->alt_pos, bca->npos); + call->mwu_mq_cdf = calc_mwu_bias_cdf(bca->ref_mq, bca->alt_mq, bca->nqual); + call->mwu_bq_cdf = calc_mwu_bias_cdf(bca->ref_bq, bca->alt_bq, bca->nqual); + call->mwu_mqs_cdf = calc_mwu_bias_cdf(bca->fwd_mqs, bca->rev_mqs, bca->nqual); +#endif + + call->vdb = calc_vdb(bca->alt_pos, bca->npos); + + return 0; +} + +int bcf_call2bcf(bcf_call_t *bc, bcf1_t *rec, bcf_callret1_t *bcr, int fmt_flag, const bcf_callaux_t *bca, const char *ref) +{ + extern double kt_fisher_exact(int n11, int n12, int n21, int n22, double *_left, double *_right, double *two); + int i, j, nals = 1; + + bcf_hdr_t *hdr = bc->bcf_hdr; + rec->rid = bc->tid; + rec->pos = bc->pos; + rec->qual = 0; + + bc->tmp.l = 0; + if (bc->ori_ref < 0) // indel + { + // REF + kputc(ref[bc->pos], &bc->tmp); + for (j = 0; j < bca->indelreg; ++j) kputc(ref[bc->pos+1+j], &bc->tmp); + + // ALT + for (i=1; i<4; i++) + { + if (bc->a[i] < 0) break; + kputc(',', &bc->tmp); kputc(ref[bc->pos], &bc->tmp); + + if (bca->indel_types[bc->a[i]] < 0) { // deletion + for (j = -bca->indel_types[bc->a[i]]; j < bca->indelreg; ++j) + kputc(ref[bc->pos+1+j], &bc->tmp); + } else { // insertion; cannot be a reference unless a bug + char *inscns = &bca->inscns[bc->a[i] * bca->maxins]; + for (j = 0; j < bca->indel_types[bc->a[i]]; ++j) + kputc("ACGTN"[(int)inscns[j]], &bc->tmp); + for (j = 0; j < bca->indelreg; ++j) kputc(ref[bc->pos+1+j], &bc->tmp); + } + nals++; + } + } + else // SNP + { + kputc("ACGTN"[bc->ori_ref], &bc->tmp); + for (i=1; i<5; i++) + { + if (bc->a[i] < 0) break; + kputc(',', &bc->tmp); + if ( bc->unseen==i ) kputs("<*>", &bc->tmp); + else kputc("ACGT"[bc->a[i]], &bc->tmp); + nals++; + } + } + bcf_update_alleles_str(hdr, rec, bc->tmp.s); + + bc->tmp.l = 0; + + // INFO + if (bc->ori_ref < 0) + { + bcf_update_info_flag(hdr, rec, "INDEL", NULL, 1); + bcf_update_info_int32(hdr, rec, "IDV", &bca->max_support, 1); + bcf_update_info_float(hdr, rec, "IMF", &bca->max_frac, 1); + } + bcf_update_info_int32(hdr, rec, "DP", &bc->ori_depth, 1); + if ( fmt_flag&B2B_INFO_ADF ) + bcf_update_info_int32(hdr, rec, "ADF", bc->ADF, rec->n_allele); + if ( fmt_flag&B2B_INFO_ADR ) + bcf_update_info_int32(hdr, rec, "ADR", bc->ADR, rec->n_allele); + if ( fmt_flag&(B2B_INFO_AD|B2B_INFO_DPR) ) + { + for (i=0; in_allele; i++) bc->ADF[i] += bc->ADR[i]; + if ( fmt_flag&B2B_INFO_AD ) + bcf_update_info_int32(hdr, rec, "AD", bc->ADF, rec->n_allele); + if ( fmt_flag&B2B_INFO_DPR ) + bcf_update_info_int32(hdr, rec, "DPR", bc->ADF, rec->n_allele); + } + + float tmpf[16]; + for (i=0; i<16; i++) tmpf[i] = bc->anno[i]; + bcf_update_info_float(hdr, rec, "I16", tmpf, 16); + bcf_update_info_float(hdr, rec, "QS", bc->qsum, nals); + + if ( bc->vdb != HUGE_VAL ) bcf_update_info_float(hdr, rec, "VDB", &bc->vdb, 1); + if ( bc->seg_bias != HUGE_VAL ) bcf_update_info_float(hdr, rec, "SGB", &bc->seg_bias, 1); + if ( bc->mwu_pos != HUGE_VAL ) bcf_update_info_float(hdr, rec, "RPB", &bc->mwu_pos, 1); + if ( bc->mwu_mq != HUGE_VAL ) bcf_update_info_float(hdr, rec, "MQB", &bc->mwu_mq, 1); + if ( bc->mwu_mqs != HUGE_VAL ) bcf_update_info_float(hdr, rec, "MQSB", &bc->mwu_mqs, 1); + if ( bc->mwu_bq != HUGE_VAL ) bcf_update_info_float(hdr, rec, "BQB", &bc->mwu_bq, 1); +#if CDF_MWU_TESTS + if ( bc->mwu_pos_cdf != HUGE_VAL ) bcf_update_info_float(hdr, rec, "RPB2", &bc->mwu_pos_cdf, 1); + if ( bc->mwu_mq_cdf != HUGE_VAL ) bcf_update_info_float(hdr, rec, "MQB2", &bc->mwu_mq_cdf, 1); + if ( bc->mwu_mqs_cdf != HUGE_VAL ) bcf_update_info_float(hdr, rec, "MQSB2", &bc->mwu_mqs_cdf, 1); + if ( bc->mwu_bq_cdf != HUGE_VAL ) bcf_update_info_float(hdr, rec, "BQB2", &bc->mwu_bq_cdf, 1); +#endif + tmpf[0] = bc->ori_depth ? (float)bc->mq0/bc->ori_depth : 0; + bcf_update_info_float(hdr, rec, "MQ0F", tmpf, 1); + + // FORMAT + rec->n_sample = bc->n; + bcf_update_format_int32(hdr, rec, "PL", bc->PL, nals*(nals+1)/2 * rec->n_sample); + if ( fmt_flag&B2B_FMT_DP ) + { + int32_t *ptr = (int32_t*) bc->fmt_arr; + for (i=0; in; i++) + ptr[i] = bc->DP4[4*i] + bc->DP4[4*i+1] + bc->DP4[4*i+2] + bc->DP4[4*i+3]; + bcf_update_format_int32(hdr, rec, "DP", bc->fmt_arr, rec->n_sample); + } + if ( fmt_flag&B2B_FMT_DV ) + { + int32_t *ptr = (int32_t*) bc->fmt_arr; + for (i=0; in; i++) + ptr[i] = bc->DP4[4*i+2] + bc->DP4[4*i+3]; + bcf_update_format_int32(hdr, rec, "DV", bc->fmt_arr, rec->n_sample); + } + if ( fmt_flag&B2B_FMT_SP ) + { + int32_t *ptr = (int32_t*) bc->fmt_arr; + for (i=0; in; i++) + { + int fwd_ref = bc->DP4[4*i], rev_ref = bc->DP4[4*i+1], fwd_alt = bc->DP4[4*i+2], rev_alt = bc->DP4[4*i+3]; + if ( fwd_ref+rev_ref<2 || fwd_alt+rev_alt<2 || fwd_ref+fwd_alt<2 || rev_ref+rev_alt<2 ) + ptr[i] = 0; + else + { + double left, right, two; + kt_fisher_exact(fwd_ref, rev_ref, fwd_alt, rev_alt, &left, &right, &two); + int32_t x = (int)(-4.343 * log(two) + .499); + if (x > 255) x = 255; + ptr[i] = x; + } + } + bcf_update_format_int32(hdr, rec, "SP", bc->fmt_arr, rec->n_sample); + } + if ( fmt_flag&B2B_FMT_DP4 ) + bcf_update_format_int32(hdr, rec, "DP4", bc->DP4, rec->n_sample*4); + if ( fmt_flag&B2B_FMT_ADF ) + bcf_update_format_int32(hdr, rec, "ADF", bc->ADF+B2B_MAX_ALLELES, rec->n_sample*rec->n_allele); + if ( fmt_flag&B2B_FMT_ADR ) + bcf_update_format_int32(hdr, rec, "ADR", bc->ADR+B2B_MAX_ALLELES, rec->n_sample*rec->n_allele); + if ( fmt_flag&(B2B_FMT_AD|B2B_FMT_DPR) ) + { + for (i=0; in_sample*rec->n_allele; i++) bc->ADF[B2B_MAX_ALLELES+i] += bc->ADR[B2B_MAX_ALLELES+i]; + if ( fmt_flag&B2B_FMT_AD ) + bcf_update_format_int32(hdr, rec, "AD", bc->ADF+B2B_MAX_ALLELES, rec->n_sample*rec->n_allele); + if ( fmt_flag&B2B_FMT_DPR ) + bcf_update_format_int32(hdr, rec, "DPR", bc->ADF+B2B_MAX_ALLELES, rec->n_sample*rec->n_allele); + } + + return 0; +} diff --git a/bam2bcf.h b/bam2bcf.h new file mode 100644 index 0000000..f81f9cf --- /dev/null +++ b/bam2bcf.h @@ -0,0 +1,138 @@ +/* bam2bcf.h -- variant calling. + + Copyright (C) 2010-2012 Broad Institute. + Copyright (C) 2012-2014,2016 Genome Research Ltd. + + Author: Heng Li + +Permission is hereby granted, free of charge, to any person obtaining a copy +of this software and associated documentation files (the "Software"), to deal +in the Software without restriction, including without limitation the rights +to use, copy, modify, merge, publish, distribute, sublicense, and/or sell +copies of the Software, and to permit persons to whom the Software is +furnished to do so, subject to the following conditions: + +The above copyright notice and this permission notice shall be included in +all copies or substantial portions of the Software. + +THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL +THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER +LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING +FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER +DEALINGS IN THE SOFTWARE. */ + +#ifndef BAM2BCF_H +#define BAM2BCF_H + +#include +#include +#include + +/** + * A simplified version of Mann-Whitney U-test is calculated + * by default (no CDF) because it is faster and seems to work + * better in machine learning filtering. When enabled by setting + * CDF_MWU_TESTS, additional annotations will appear on mpileup's + * output (RPB2 in addition to RPB, etc.). + */ +#ifndef CDF_MWU_TESTS +#define CDF_MWU_TESTS 0 +#endif + +#define B2B_INDEL_NULL 10000 + +#define B2B_FMT_DP (1<<0) +#define B2B_FMT_SP (1<<1) +#define B2B_FMT_DV (1<<2) +#define B2B_FMT_DP4 (1<<3) +#define B2B_FMT_DPR (1<<4) +#define B2B_INFO_DPR (1<<5) +#define B2B_FMT_AD (1<<6) +#define B2B_FMT_ADF (1<<7) +#define B2B_FMT_ADR (1<<8) +#define B2B_INFO_AD (1<<9) +#define B2B_INFO_ADF (1<<10) +#define B2B_INFO_ADR (1<<11) + +#define B2B_MAX_ALLELES 5 + +typedef struct __bcf_callaux_t { + int capQ, min_baseQ; + int openQ, extQ, tandemQ; // for indels + uint32_t min_support, max_support; // for collecting indel candidates + double min_frac; // for collecting indel candidates + float max_frac; // for collecting indel candidates + int per_sample_flt; // indel filtering strategy + int *ref_pos, *alt_pos, npos, *ref_mq, *alt_mq, *ref_bq, *alt_bq, *fwd_mqs, *rev_mqs, nqual; // for bias tests + // for internal uses + int max_bases; + int indel_types[4]; // indel lengths + int maxins, indelreg; + int read_len; + char *inscns; + uint16_t *bases; // 5bit: unused, 6:quality, 1:is_rev, 4:2-bit base or indel allele (index to bcf_callaux_t.indel_types) + errmod_t *e; + void *rghash; +} bcf_callaux_t; + +typedef struct { + uint32_t ori_depth; + unsigned int mq0; + int32_t *ADF, *ADR; + float qsum[4]; + // The fields are: + // depth fwd .. ref (0) and non-ref (2) + // depth rev .. ref (1) and non-ref (3) + // baseQ .. ref (4) and non-ref (6) + // baseQ^2 .. ref (5) and non-ref (7) + // mapQ .. ref (8) and non-ref (10) + // mapQ^2 .. ref (9) and non-ref (11) + // minDist .. ref (12) and non-ref (14) + // minDist^2 .. ref (13) and non-ref (15) + // Note that this probably needs a more thorough fix: int types in + // bcf_call_t do overflow with high-coverage data, such as exomes, and + // BCFv2 supports only floats which may not suffice. + double anno[16]; + float p[25]; // phred-scaled likelihood of each genotype +} bcf_callret1_t; + +typedef struct { + int tid, pos; + bcf_hdr_t *bcf_hdr; + int a[5]; // alleles: ref, alt, alt2, alt3 + float qsum[5]; // for the QS tag + int n, n_alleles, shift, ori_ref, unseen; + int n_supp; // number of supporting non-reference reads + double anno[16]; + unsigned int depth, ori_depth, mq0; + int32_t *PL, *DP4, *ADR, *ADF; + uint8_t *fmt_arr; + float vdb; // variant distance bias + float mwu_pos, mwu_mq, mwu_bq, mwu_mqs; +#if CDF_MWU_TESTS + float mwu_pos_cdf, mwu_mq_cdf, mwu_bq_cdf, mwu_mqs_cdf; +#endif + float seg_bias; + kstring_t tmp; +} bcf_call_t; + +#ifdef __cplusplus +extern "C" { +#endif + + bcf_callaux_t *bcf_call_init(double theta, int min_baseQ); + void bcf_call_destroy(bcf_callaux_t *bca); + int bcf_call_glfgen(int _n, const bam_pileup1_t *pl, int ref_base, bcf_callaux_t *bca, bcf_callret1_t *r); + int bcf_call_combine(int n, const bcf_callret1_t *calls, bcf_callaux_t *bca, int ref_base /*4-bit*/, bcf_call_t *call); + int bcf_call2bcf(bcf_call_t *bc, bcf1_t *b, bcf_callret1_t *bcr, int fmt_flag, + const bcf_callaux_t *bca, const char *ref); + int bcf_call_gap_prep(int n, int *n_plp, bam_pileup1_t **plp, int pos, bcf_callaux_t *bca, const char *ref); + void bcf_callaux_clean(bcf_callaux_t *bca, bcf_call_t *call); + +#ifdef __cplusplus +} +#endif + +#endif diff --git a/bam2bcf_indel.c b/bam2bcf_indel.c new file mode 100644 index 0000000..52837b5 --- /dev/null +++ b/bam2bcf_indel.c @@ -0,0 +1,470 @@ +/* bam2bcf_indel.c -- indel caller. + + Copyright (C) 2010, 2011 Broad Institute. + Copyright (C) 2012-2014,2016 Genome Research Ltd. + + Author: Heng Li + +Permission is hereby granted, free of charge, to any person obtaining a copy +of this software and associated documentation files (the "Software"), to deal +in the Software without restriction, including without limitation the rights +to use, copy, modify, merge, publish, distribute, sublicense, and/or sell +copies of the Software, and to permit persons to whom the Software is +furnished to do so, subject to the following conditions: + +The above copyright notice and this permission notice shall be included in +all copies or substantial portions of the Software. + +THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL +THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER +LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING +FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER +DEALINGS IN THE SOFTWARE. */ + +#include +#include +#include +#include +#include +#include +#include "bam2bcf.h" + +#include +KSORT_INIT_GENERIC(uint32_t) + +#define MINUS_CONST 0x10000000 +#define INDEL_WINDOW_SIZE 50 + +static int tpos2qpos(const bam1_core_t *c, const uint32_t *cigar, int32_t tpos, int is_left, int32_t *_tpos) +{ + int k, x = c->pos, y = 0, last_y = 0; + *_tpos = c->pos; + for (k = 0; k < c->n_cigar; ++k) { + int op = cigar[k] & BAM_CIGAR_MASK; + int l = cigar[k] >> BAM_CIGAR_SHIFT; + if (op == BAM_CMATCH || op == BAM_CEQUAL || op == BAM_CDIFF) { + if (c->pos > tpos) return y; + if (x + l > tpos) { + *_tpos = tpos; + return y + (tpos - x); + } + x += l; y += l; + last_y = y; + } else if (op == BAM_CINS || op == BAM_CSOFT_CLIP) y += l; + else if (op == BAM_CDEL || op == BAM_CREF_SKIP) { + if (x + l > tpos) { + *_tpos = is_left? x : x + l; + return y; + } + x += l; + } + } + *_tpos = x; + return last_y; +} +// FIXME: check if the inserted sequence is consistent with the homopolymer run +// l is the relative gap length and l_run is the length of the homopolymer on the reference +static inline int est_seqQ(const bcf_callaux_t *bca, int l, int l_run) +{ + int q, qh; + q = bca->openQ + bca->extQ * (abs(l) - 1); + qh = l_run >= 3? (int)(bca->tandemQ * (double)abs(l) / l_run + .499) : 1000; + return q < qh? q : qh; +} + +static inline int est_indelreg(int pos, const char *ref, int l, char *ins4) +{ + int i, j, max = 0, max_i = pos, score = 0; + l = abs(l); + for (i = pos + 1, j = 0; ref[i]; ++i, ++j) { + if (ins4) score += (toupper(ref[i]) != "ACGTN"[(int)ins4[j%l]])? -10 : 1; + else score += (toupper(ref[i]) != toupper(ref[pos+1+j%l]))? -10 : 1; + if (score < 0) break; + if (max < score) max = score, max_i = i; + } + return max_i - pos; +} + +/* + notes: + - n .. number of samples + - the routine sets bam_pileup1_t.aux of each read as follows: + - 6: unused + - 6: the call; index to bcf_callaux_t.indel_types .. (aux>>16)&0x3f + - 8: estimated sequence quality .. (aux>>8)&0xff + - 8: indel quality .. aux&0xff + */ +int bcf_call_gap_prep(int n, int *n_plp, bam_pileup1_t **plp, int pos, bcf_callaux_t *bca, const char *ref) +{ + int i, s, j, k, t, n_types, *types, max_rd_len, left, right, max_ins, *score1, *score2, max_ref2; + int N, K, l_run, ref_type, n_alt; + char *inscns = 0, *ref2, *query, **ref_sample; + if (ref == 0 || bca == 0) return -1; + + // determine if there is a gap + for (s = N = 0; s < n; ++s) { + for (i = 0; i < n_plp[s]; ++i) + if (plp[s][i].indel != 0) break; + if (i < n_plp[s]) break; + } + if (s == n) return -1; // there is no indel at this position. + for (s = N = 0; s < n; ++s) N += n_plp[s]; // N is the total number of reads + { // find out how many types of indels are present + bca->max_support = bca->max_frac = 0; + int m, n_alt = 0, n_tot = 0, indel_support_ok = 0; + uint32_t *aux; + aux = (uint32_t*) calloc(N + 1, 4); + m = max_rd_len = 0; + aux[m++] = MINUS_CONST; // zero indel is always a type + for (s = 0; s < n; ++s) { + int na = 0, nt = 0; + for (i = 0; i < n_plp[s]; ++i) { + const bam_pileup1_t *p = plp[s] + i; + ++nt; + if (p->indel != 0) { + ++na; + aux[m++] = MINUS_CONST + p->indel; + } + j = bam_cigar2qlen(p->b->core.n_cigar, bam_get_cigar(p->b)); + if (j > max_rd_len) max_rd_len = j; + } + double frac = (double)na/nt; + if ( !indel_support_ok && na >= bca->min_support && frac >= bca->min_frac ) + indel_support_ok = 1; + if ( na > bca->max_support && frac > 0 ) bca->max_support = na, bca->max_frac = frac; + n_alt += na; + n_tot += nt; + } + // To prevent long stretches of N's to be mistaken for indels (sometimes thousands of bases), + // check the number of N's in the sequence and skip places where half or more reference bases are Ns. + int nN=0; for (i=pos; i-pos(i-pos) ) { free(aux); return -1; } + + ks_introsort(uint32_t, m, aux); + // squeeze out identical types + for (i = 1, n_types = 1; i < m; ++i) + if (aux[i] != aux[i-1]) ++n_types; + // Taking totals makes it hard to call rare indels + if ( !bca->per_sample_flt ) + indel_support_ok = ( (double)n_alt / n_tot < bca->min_frac || n_alt < bca->min_support ) ? 0 : 1; + if ( n_types == 1 || !indel_support_ok ) { // then skip + free(aux); return -1; + } + if (n_types >= 64) { + free(aux); + // TODO revisit how/whether to control printing this warning + if (hts_verbose >= 2) + fprintf(stderr, "[%s] excessive INDEL alleles at position %d. Skip the position.\n", __func__, pos + 1); + return -1; + } + types = (int*)calloc(n_types, sizeof(int)); + t = 0; + types[t++] = aux[0] - MINUS_CONST; + for (i = 1; i < m; ++i) + if (aux[i] != aux[i-1]) + types[t++] = aux[i] - MINUS_CONST; + free(aux); + for (t = 0; t < n_types; ++t) + if (types[t] == 0) break; + ref_type = t; // the index of the reference type (0) + } + { // calculate left and right boundary + left = pos > INDEL_WINDOW_SIZE? pos - INDEL_WINDOW_SIZE : 0; + right = pos + INDEL_WINDOW_SIZE; + if (types[0] < 0) right -= types[0]; + // in case the alignments stand out the reference + for (i = pos; i < right; ++i) + if (ref[i] == 0) break; + right = i; + } + /* The following block fixes a long-existing flaw in the INDEL + * calling model: the interference of nearby SNPs. However, it also + * reduces the power because sometimes, substitutions caused by + * indels are not distinguishable from true mutations. Multiple + * sequence realignment helps to increase the power. + * + * Masks mismatches present in at least 70% of the reads with 'N'. + */ + { // construct per-sample consensus + int L = right - left + 1, max_i, max2_i; + uint32_t *cns, max, max2; + char *ref0, *r; + ref_sample = (char**) calloc(n, sizeof(char*)); + cns = (uint32_t*) calloc(L, 4); + ref0 = (char*) calloc(L, 1); + for (i = 0; i < right - left; ++i) + ref0[i] = seq_nt16_table[(int)ref[i+left]]; + for (s = 0; s < n; ++s) { + r = ref_sample[s] = (char*) calloc(L, 1); + memset(cns, 0, sizeof(int) * L); + // collect ref and non-ref counts + for (i = 0; i < n_plp[s]; ++i) { + bam_pileup1_t *p = plp[s] + i; + bam1_t *b = p->b; + uint32_t *cigar = bam_get_cigar(b); + uint8_t *seq = bam_get_seq(b); + int x = b->core.pos, y = 0; + for (k = 0; k < b->core.n_cigar; ++k) { + int op = cigar[k]&0xf; + int j, l = cigar[k]>>4; + if (op == BAM_CMATCH || op == BAM_CEQUAL || op == BAM_CDIFF) { + for (j = 0; j < l; ++j) + if (x + j >= left && x + j < right) + cns[x+j-left] += (bam_seqi(seq, y+j) == ref0[x+j-left])? 1 : 0x10000; + x += l; y += l; + } else if (op == BAM_CDEL || op == BAM_CREF_SKIP) x += l; + else if (op == BAM_CINS || op == BAM_CSOFT_CLIP) y += l; + } + } + // determine the consensus + for (i = 0; i < right - left; ++i) r[i] = ref0[i]; + max = max2 = 0; max_i = max2_i = -1; + for (i = 0; i < right - left; ++i) { + if (cns[i]>>16 >= max>>16) max2 = max, max2_i = max_i, max = cns[i], max_i = i; + else if (cns[i]>>16 >= max2>>16) max2 = cns[i], max2_i = i; + } + if ((double)(max&0xffff) / ((max&0xffff) + (max>>16)) >= 0.7) max_i = -1; + if ((double)(max2&0xffff) / ((max2&0xffff) + (max2>>16)) >= 0.7) max2_i = -1; + if (max_i >= 0) r[max_i] = 15; + if (max2_i >= 0) r[max2_i] = 15; + //for (i = 0; i < right - left; ++i) fputc("=ACMGRSVTWYHKDBN"[(int)r[i]], stderr); fputc('\n', stderr); + } + free(ref0); free(cns); + } + { // the length of the homopolymer run around the current position + int c = seq_nt16_table[(int)ref[pos + 1]]; + if (c == 15) l_run = 1; + else { + for (i = pos + 2; ref[i]; ++i) + if (seq_nt16_table[(int)ref[i]] != c) break; + l_run = i; + for (i = pos; i >= 0; --i) + if (seq_nt16_table[(int)ref[i]] != c) break; + l_run -= i + 1; + } + } + // construct the consensus sequence + max_ins = types[n_types - 1]; // max_ins is at least 0 + if (max_ins > 0) { + int *inscns_aux = (int*) calloc(5 * n_types * max_ins, sizeof(int)); + // count the number of occurrences of each base at each position for each type of insertion + for (t = 0; t < n_types; ++t) { + if (types[t] > 0) { + for (s = 0; s < n; ++s) { + for (i = 0; i < n_plp[s]; ++i) { + bam_pileup1_t *p = plp[s] + i; + if (p->indel == types[t]) { + uint8_t *seq = bam_get_seq(p->b); + for (k = 1; k <= p->indel; ++k) { + int c = seq_nt16_int[bam_seqi(seq, p->qpos + k)]; + assert(c<5); + ++inscns_aux[(t*max_ins+(k-1))*5 + c]; + } + } + } + } + } + } + // use the majority rule to construct the consensus + inscns = (char*) calloc(n_types * max_ins, 1); + for (t = 0; t < n_types; ++t) { + for (j = 0; j < types[t]; ++j) { + int max = 0, max_k = -1, *ia = &inscns_aux[(t*max_ins+j)*5]; + for (k = 0; k < 5; ++k) + if (ia[k] > max) + max = ia[k], max_k = k; + inscns[t*max_ins + j] = max? max_k : 4; + if ( max_k==4 ) { types[t] = 0; break; } // discard insertions which contain N's + } + } + free(inscns_aux); + } + // compute the likelihood given each type of indel for each read + max_ref2 = right - left + 2 + 2 * (max_ins > -types[0]? max_ins : -types[0]); + ref2 = (char*) calloc(max_ref2, 1); + query = (char*) calloc(right - left + max_rd_len + max_ins + 2, 1); + score1 = (int*) calloc(N * n_types, sizeof(int)); + score2 = (int*) calloc(N * n_types, sizeof(int)); + bca->indelreg = 0; + for (t = 0; t < n_types; ++t) { + int l, ir; + probaln_par_t apf1 = { 1e-4, 1e-2, 10 }, apf2 = { 1e-6, 1e-3, 10 }; + apf1.bw = apf2.bw = abs(types[t]) + 3; + // compute indelreg + if (types[t] == 0) ir = 0; + else if (types[t] > 0) ir = est_indelreg(pos, ref, types[t], &inscns[t*max_ins]); + else ir = est_indelreg(pos, ref, -types[t], 0); + if (ir > bca->indelreg) bca->indelreg = ir; +// fprintf(stderr, "%d, %d, %d\n", pos, types[t], ir); + // realignment + for (s = K = 0; s < n; ++s) { + // write ref2 + for (k = 0, j = left; j <= pos; ++j) + ref2[k++] = seq_nt16_int[(int)ref_sample[s][j-left]]; + if (types[t] <= 0) j += -types[t]; + else for (l = 0; l < types[t]; ++l) + ref2[k++] = inscns[t*max_ins + l]; + for (; j < right && ref[j]; ++j) + ref2[k++] = seq_nt16_int[(int)ref_sample[s][j-left]]; + for (; k < max_ref2; ++k) ref2[k] = 4; + if (j < right) right = j; + // align each read to ref2 + for (i = 0; i < n_plp[s]; ++i, ++K) { + bam_pileup1_t *p = plp[s] + i; + int qbeg, qend, tbeg, tend, sc, kk; + uint8_t *seq = bam_get_seq(p->b); + uint32_t *cigar = bam_get_cigar(p->b); + if (p->b->core.flag&4) continue; // unmapped reads + // FIXME: the following loop should be better moved outside; nonetheless, realignment should be much slower anyway. + for (kk = 0; kk < p->b->core.n_cigar; ++kk) + if ((cigar[kk]&BAM_CIGAR_MASK) == BAM_CREF_SKIP) break; + if (kk < p->b->core.n_cigar) continue; + // FIXME: the following skips soft clips, but using them may be more sensitive. + // determine the start and end of sequences for alignment + qbeg = tpos2qpos(&p->b->core, bam_get_cigar(p->b), left, 0, &tbeg); + qend = tpos2qpos(&p->b->core, bam_get_cigar(p->b), right, 1, &tend); + if (types[t] < 0) { + int l = -types[t]; + tbeg = tbeg - l > left? tbeg - l : left; + } + // write the query sequence + for (l = qbeg; l < qend; ++l) + query[l - qbeg] = seq_nt16_int[bam_seqi(seq, l)]; + { // do realignment; this is the bottleneck + const uint8_t *qual = bam_get_qual(p->b), *bq; + uint8_t *qq; + qq = (uint8_t*) calloc(qend - qbeg, 1); + bq = (uint8_t*)bam_aux_get(p->b, "ZQ"); + if (bq) ++bq; // skip type + for (l = qbeg; l < qend; ++l) { + qq[l - qbeg] = bq? qual[l] + (bq[l] - 64) : qual[l]; + if (qq[l - qbeg] > 30) qq[l - qbeg] = 30; + if (qq[l - qbeg] < 7) qq[l - qbeg] = 7; + } + sc = probaln_glocal((uint8_t*)ref2 + tbeg - left, tend - tbeg + abs(types[t]), + (uint8_t*)query, qend - qbeg, qq, &apf1, 0, 0); + l = (int)(100. * sc / (qend - qbeg) + .499); // used for adjusting indelQ below + if (l > 255) l = 255; + score1[K*n_types + t] = score2[K*n_types + t] = sc<<8 | l; + if (sc > 5) { + sc = probaln_glocal((uint8_t*)ref2 + tbeg - left, tend - tbeg + abs(types[t]), + (uint8_t*)query, qend - qbeg, qq, &apf2, 0, 0); + l = (int)(100. * sc / (qend - qbeg) + .499); + if (l > 255) l = 255; + score2[K*n_types + t] = sc<<8 | l; + } + free(qq); + } +/* + for (l = 0; l < tend - tbeg + abs(types[t]); ++l) + fputc("ACGTN"[(int)ref2[tbeg-left+l]], stderr); + fputc('\n', stderr); + for (l = 0; l < qend - qbeg; ++l) fputc("ACGTN"[(int)query[l]], stderr); + fputc('\n', stderr); + fprintf(stderr, "pos=%d type=%d read=%d:%d name=%s qbeg=%d tbeg=%d score=%d\n", pos, types[t], s, i, bam1_qname(p->b), qbeg, tbeg, sc); +*/ + } + } + } + free(ref2); free(query); + { // compute indelQ + int sc_a[16], sumq_a[16]; + int tmp, *sc = sc_a, *sumq = sumq_a; + if (n_types > 16) { + sc = (int *)malloc(n_types * sizeof(int)); + sumq = (int *)malloc(n_types * sizeof(int)); + } + memset(sumq, 0, n_types * sizeof(int)); + for (s = K = 0; s < n; ++s) { + for (i = 0; i < n_plp[s]; ++i, ++K) { + bam_pileup1_t *p = plp[s] + i; + int *sct = &score1[K*n_types], indelQ1, indelQ2, seqQ, indelQ; + for (t = 0; t < n_types; ++t) sc[t] = sct[t]<<6 | t; + for (t = 1; t < n_types; ++t) // insertion sort + for (j = t; j > 0 && sc[j] < sc[j-1]; --j) + tmp = sc[j], sc[j] = sc[j-1], sc[j-1] = tmp; + /* errmod_cal() assumes that if the call is wrong, the + * likelihoods of other events are equal. This is about + * right for substitutions, but is not desired for + * indels. To reuse errmod_cal(), I have to make + * compromise for multi-allelic indels. + */ + if ((sc[0]&0x3f) == ref_type) { + indelQ1 = (sc[1]>>14) - (sc[0]>>14); + seqQ = est_seqQ(bca, types[sc[1]&0x3f], l_run); + } else { + for (t = 0; t < n_types; ++t) // look for the reference type + if ((sc[t]&0x3f) == ref_type) break; + indelQ1 = (sc[t]>>14) - (sc[0]>>14); + seqQ = est_seqQ(bca, types[sc[0]&0x3f], l_run); + } + tmp = sc[0]>>6 & 0xff; + indelQ1 = tmp > 111? 0 : (int)((1. - tmp/111.) * indelQ1 + .499); // reduce indelQ + sct = &score2[K*n_types]; + for (t = 0; t < n_types; ++t) sc[t] = sct[t]<<6 | t; + for (t = 1; t < n_types; ++t) // insertion sort + for (j = t; j > 0 && sc[j] < sc[j-1]; --j) + tmp = sc[j], sc[j] = sc[j-1], sc[j-1] = tmp; + if ((sc[0]&0x3f) == ref_type) { + indelQ2 = (sc[1]>>14) - (sc[0]>>14); + } else { + for (t = 0; t < n_types; ++t) // look for the reference type + if ((sc[t]&0x3f) == ref_type) break; + indelQ2 = (sc[t]>>14) - (sc[0]>>14); + } + tmp = sc[0]>>6 & 0xff; + indelQ2 = tmp > 111? 0 : (int)((1. - tmp/111.) * indelQ2 + .499); + // pick the smaller between indelQ1 and indelQ2 + indelQ = indelQ1 < indelQ2? indelQ1 : indelQ2; + if (indelQ > 255) indelQ = 255; + if (seqQ > 255) seqQ = 255; + p->aux = (sc[0]&0x3f)<<16 | seqQ<<8 | indelQ; // use 22 bits in total + sumq[sc[0]&0x3f] += indelQ < seqQ? indelQ : seqQ; +// fprintf(stderr, "pos=%d read=%d:%d name=%s call=%d indelQ=%d seqQ=%d\n", pos, s, i, bam1_qname(p->b), types[sc[0]&0x3f], indelQ, seqQ); + } + } + // determine bca->indel_types[] and bca->inscns + bca->maxins = max_ins; + bca->inscns = (char*) realloc(bca->inscns, bca->maxins * 4); + for (t = 0; t < n_types; ++t) + sumq[t] = sumq[t]<<6 | t; + for (t = 1; t < n_types; ++t) // insertion sort + for (j = t; j > 0 && sumq[j] > sumq[j-1]; --j) + tmp = sumq[j], sumq[j] = sumq[j-1], sumq[j-1] = tmp; + for (t = 0; t < n_types; ++t) // look for the reference type + if ((sumq[t]&0x3f) == ref_type) break; + if (t) { // then move the reference type to the first + tmp = sumq[t]; + for (; t > 0; --t) sumq[t] = sumq[t-1]; + sumq[0] = tmp; + } + for (t = 0; t < 4; ++t) bca->indel_types[t] = B2B_INDEL_NULL; + for (t = 0; t < 4 && t < n_types; ++t) { + bca->indel_types[t] = types[sumq[t]&0x3f]; + memcpy(&bca->inscns[t * bca->maxins], &inscns[(sumq[t]&0x3f) * max_ins], bca->maxins); + } + // update p->aux + for (s = n_alt = 0; s < n; ++s) { + for (i = 0; i < n_plp[s]; ++i) { + bam_pileup1_t *p = plp[s] + i; + int x = types[p->aux>>16&0x3f]; + for (j = 0; j < 4; ++j) + if (x == bca->indel_types[j]) break; + p->aux = j<<16 | (j == 4? 0 : (p->aux&0xffff)); + if ((p->aux>>16&0x3f) > 0) ++n_alt; + //fprintf(stderr, "X pos=%d read=%d:%d name=%s call=%d type=%d seqQ=%d indelQ=%d\n", pos, s, i, bam1_qname(p->b), (p->aux>>16)&0x3f, bca->indel_types[(p->aux>>16)&0x3f], (p->aux>>8)&0xff, p->aux&0xff); + } + } + + if (sc != sc_a) free(sc); + if (sumq != sumq_a) free(sumq); + } + free(score1); free(score2); + // free + for (i = 0; i < n; ++i) free(ref_sample[i]); + free(ref_sample); + free(types); free(inscns); + return n_alt > 0? 0 : -1; +} diff --git a/bam_sample.c b/bam_sample.c new file mode 100644 index 0000000..66f5729 --- /dev/null +++ b/bam_sample.c @@ -0,0 +1,393 @@ +/* bam_sample.c -- group data by sample. + + Copyright (C) 2010, 2011 Broad Institute. + Copyright (C) 2013, 2016 Genome Research Ltd. + + Author: Heng Li , Petr Danecek + +Permission is hereby granted, free of charge, to any person obtaining a copy +of this software and associated documentation files (the "Software"), to deal +in the Software without restriction, including without limitation the rights +to use, copy, modify, merge, publish, distribute, sublicense, and/or sell +copies of the Software, and to permit persons to whom the Software is +furnished to do so, subject to the following conditions: + +The above copyright notice and this permission notice shall be included in +all copies or substantial portions of the Software. + +THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL +THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER +LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING +FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER +DEALINGS IN THE SOFTWARE. */ + +#include +#include +#include +#include +#include +#include +#include +#include "bam_sample.h" +#include "bcftools.h" + + +typedef struct +{ + char *fname; + void *rg2idx; // hash: read group name to BCF output sample index. Maintained by bsmpl_add_readgroup + int default_idx; // default BCF output sample index, set only when all readgroups are treated as one sample +} +file_t; + +struct _bam_smpl_t +{ + kstring_t tmp; + file_t *files; + int ignore_rg, nsmpl, nfiles; + char **smpl; // list of BCF output sample names. Maintained by bsmpl_add_readgroup + void *sample_list; // hash: BAM input sample name to BCF output sample name. This is the -s/-S list + int sample_logic; // the -s/-S logic, 1: include, 0: exclude + void *rg_list; // hash: BAM/rg_id to sample name or */rg_id for global ids. This is the -G list + int rg_logic; // the -G logic, 1: include, 0: exclude + void *name2idx; // hash: BCF output sample name to BCF output sample index. Maintained by bsmpl_add_readgroup +}; + +bam_smpl_t *bam_smpl_init(void) +{ + bam_smpl_t *bsmpl; + bsmpl = (bam_smpl_t*) calloc(1, sizeof(bam_smpl_t)); + bsmpl->name2idx = khash_str2int_init(); + return bsmpl; +} + +void bam_smpl_destroy(bam_smpl_t *bsmpl) +{ + if ( !bsmpl ) return; + if ( bsmpl->name2idx ) khash_str2int_destroy_free(bsmpl->name2idx); + if ( bsmpl->sample_list ) khash_str2str_destroy_free_all(bsmpl->sample_list); + if ( bsmpl->rg_list ) khash_str2str_destroy_free_all(bsmpl->rg_list); + int i; + for (i=0; infiles; i++) + { + file_t *file = &bsmpl->files[i]; + if ( file->rg2idx ) khash_str2int_destroy_free(file->rg2idx); + free(file->fname); + } + free(bsmpl->smpl); + free(bsmpl->files); + free(bsmpl->tmp.s); + free(bsmpl); +} + +void bam_smpl_ignore_readgroups(bam_smpl_t* bsmpl) +{ + bsmpl->ignore_rg = 1; +} + +static void bsmpl_add_readgroup(bam_smpl_t *bsmpl, file_t *file, const char *rg_id, const char *smpl_name) +{ + int ismpl = -1; + if ( smpl_name ) + { + if ( khash_str2int_get(bsmpl->name2idx,smpl_name,&ismpl) < 0 ) + { + // new sample + bsmpl->nsmpl++; + bsmpl->smpl = (char**) realloc(bsmpl->smpl,sizeof(char*)*bsmpl->nsmpl); + bsmpl->smpl[bsmpl->nsmpl-1] = strdup(smpl_name); + ismpl = khash_str2int_inc(bsmpl->name2idx,bsmpl->smpl[bsmpl->nsmpl-1]); + } + } + if ( !strcmp("*",rg_id) ) + { + // all read groups in the bam treated as the same sample + file->default_idx = ismpl; + return; + } + if ( !file->rg2idx ) file->rg2idx = khash_str2int_init(); + if ( khash_str2int_has_key(file->rg2idx,rg_id) ) return; // duplicate @RG:ID + khash_str2int_set(file->rg2idx, strdup(rg_id), ismpl); +} +static int bsmpl_keep_readgroup(bam_smpl_t *bsmpl, file_t *file, const char *rg_id, const char **smpl_name) +{ + char *rg_smpl = khash_str2str_get(bsmpl->rg_list,rg_id); // unique read group present in one bam only + if ( !rg_smpl ) + { + // read group specific to this bam + bsmpl->tmp.l = 0; + ksprintf(&bsmpl->tmp,"%s\t%s",rg_id,file->fname); + rg_smpl = khash_str2str_get(bsmpl->rg_list,bsmpl->tmp.s); + } + if ( !rg_smpl ) + { + // any read group in this file? + bsmpl->tmp.l = 0; + ksprintf(&bsmpl->tmp,"*\t%s",file->fname); + rg_smpl = khash_str2str_get(bsmpl->rg_list,bsmpl->tmp.s); + } + if ( !rg_smpl && bsmpl->rg_logic ) return 0; + if ( rg_smpl && !bsmpl->rg_logic ) return 0; + + if ( rg_smpl && rg_smpl[0]!='\t' ) *smpl_name = rg_smpl; // rename the sample + return 1; +} + +/* + The logic of this function is a bit complicated because we want to work + also with broken bams containing read groups that are not listed in the + header. The desired behavior is as follows: + - when -G is given, read groups which are not listed in the header must + be given explicitly using the "?" symbol in -G. + Otherwise: + - if the bam has no header, all reads in the file are assigned to a + single sample named after the file + - if there is at least one sample defined in the header, reads with no + read group id or with a read group id not listed in the header are + assigned to the first sample encountered in the header +*/ +int bam_smpl_add_bam(bam_smpl_t *bsmpl, char *bam_hdr, const char *fname) +{ + bsmpl->nfiles++; + bsmpl->files = (file_t*) realloc(bsmpl->files,bsmpl->nfiles*sizeof(file_t)); + file_t *file = &bsmpl->files[bsmpl->nfiles-1]; + memset(file,0,sizeof(file_t)); + file->fname = strdup(fname); + file->default_idx = -1; + + if ( bsmpl->ignore_rg || !bam_hdr ) + { + // The option --ignore-RG is set or there is no BAM header: use the file name as the sample name + bsmpl_add_readgroup(bsmpl,file,"*",file->fname); + return bsmpl->nfiles-1; + } + + void *bam_smpls = khash_str2int_init(); + int first_smpl = -1, nskipped = 0; + const char *p = bam_hdr, *q, *r; + while ((q = strstr(p, "@RG")) != 0) + { + p = q + 3; + r = q = 0; + if ((q = strstr(p, "\tID:")) != 0) q += 4; + if ((r = strstr(p, "\tSM:")) != 0) r += 4; + if (r && q) + { + char *u, *v; + int ioq, ior; + for (u = (char*)q; *u && *u != '\t' && *u != '\n'; ++u); + for (v = (char*)r; *v && *v != '\t' && *v != '\n'; ++v); + ioq = *u; ior = *v; *u = *v = '\0'; + + // q now points to a null terminated read group id + // r points to a null terminated sample name + if ( !strcmp("*",q) || !strcmp("?",q) ) + error("Error: the read group IDs \"*\" and \"?\" have a special meaning in the mpileup code. Please fix the code or the bam: %s\n", fname); + + int accept_rg = 1; + if ( bsmpl->sample_list ) + { + // restrict samples based on the -s/-S options + char *name = khash_str2str_get(bsmpl->sample_list,r); + if ( bsmpl->sample_logic==0 ) + accept_rg = name ? 0 : 1; + else if ( !name ) + accept_rg = 0; + else + r = name; + } + if ( accept_rg && bsmpl->rg_list ) + { + // restrict readgroups based on the -G option, possibly renaming the sample + accept_rg = bsmpl_keep_readgroup(bsmpl,file,q,&r); + } + if ( accept_rg ) + bsmpl_add_readgroup(bsmpl,file,q,r); + else + { + bsmpl_add_readgroup(bsmpl,file,q,NULL); // ignore this RG but note that it was seen in the header + nskipped++; + } + + if ( first_smpl<0 ) + khash_str2int_get(bsmpl->name2idx,r,&first_smpl); + if ( !khash_str2int_has_key(bam_smpls,r) ) + khash_str2int_inc(bam_smpls,strdup(r)); + + *u = ioq; *v = ior; + } + else + break; + p = q > r ? q : r; + } + int nsmpls = khash_str2int_size(bam_smpls); + khash_str2int_destroy_free(bam_smpls); + + const char *smpl_name = NULL; + int accept_null_rg = 1; + if ( bsmpl->rg_list && !bsmpl_keep_readgroup(bsmpl,file,"?",&smpl_name) ) accept_null_rg = 0; + if ( bsmpl->sample_list && first_smpl==-1 ) accept_null_rg = 0; + + if ( !accept_null_rg && first_smpl==-1 ) + { + // no suitable read group is available in this bam: ignore the whole file. + free(file->fname); + bsmpl->nfiles--; + return -1; + } + if ( !accept_null_rg ) return bsmpl->nfiles-1; + if ( nsmpls==1 && !nskipped ) + { + file->default_idx = first_smpl; + return bsmpl->nfiles-1; + } + if ( !smpl_name ) smpl_name = first_smpl==-1 ? file->fname : bsmpl->smpl[first_smpl]; + + bsmpl_add_readgroup(bsmpl,file,"?",smpl_name); + return bsmpl->nfiles-1; +} + +const char **bam_smpl_get_samples(bam_smpl_t *bsmpl, int *nsmpl) +{ + *nsmpl = bsmpl->nsmpl; + return (const char**)bsmpl->smpl; +} + +int bam_smpl_get_sample_id(bam_smpl_t *bsmpl, int bam_id, bam1_t *bam_rec) +{ + file_t *file = &bsmpl->files[bam_id]; + if ( file->default_idx >= 0 ) return file->default_idx; + + char *aux_rg = (char*) bam_aux_get(bam_rec, "RG"); + aux_rg = aux_rg ? aux_rg+1 : "?"; + + int rg_id; + if ( khash_str2int_get(file->rg2idx, aux_rg, &rg_id)==0 ) return rg_id; + if ( khash_str2int_get(file->rg2idx, "?", &rg_id)==0 ) return rg_id; + return -1; +} + +int bam_smpl_add_samples(bam_smpl_t *bsmpl, char *list, int is_file) +{ + if ( list[0]!='^' ) bsmpl->sample_logic = 1; + else list++; + + int i, nsamples = 0; + char **samples = hts_readlist(list, is_file, &nsamples); + if ( !nsamples ) return 0; + + kstring_t ori = {0,0,0}; + kstring_t ren = {0,0,0}; + + bsmpl->sample_list = khash_str2str_init(); + for (i=0; isample_list,strdup(ori.s),strdup(ren.l?ren.s:ori.s)); + free(samples[i]); + } + free(samples); + free(ori.s); + free(ren.s); + return nsamples; +} + +int bam_smpl_add_readgroups(bam_smpl_t *bsmpl, char *list, int is_file) +{ + if ( list[0]!='^' ) bsmpl->rg_logic = 1; + else list++; + + int i, nrows = 0; + char **rows = hts_readlist(list, is_file, &nrows); + if ( !nrows ) return 0; + + kstring_t fld1 = {0,0,0}; + kstring_t fld2 = {0,0,0}; + kstring_t fld3 = {0,0,0}; + + bsmpl->rg_list = khash_str2str_init(); + for (i=0; irg_list,fld1.s); + if ( !value ) + khash_str2str_set(bsmpl->rg_list,strdup(fld1.s),strdup(fld2.l?fld2.s:"\t")); + else if ( strcmp(value,fld2.l?fld2.s:"\t") ) + error("Error: The read group \"%s\" was assigned to two different samples: \"%s\" and \"%s\"\n", fld1.s,value,fld2.l?fld2.s:"\t"); + free(rows[i]); + } + free(rows); + free(fld1.s); + free(fld2.s); + free(fld3.s); + return nrows; +} + + diff --git a/bam_sample.h b/bam_sample.h new file mode 100644 index 0000000..5cbcc39 --- /dev/null +++ b/bam_sample.h @@ -0,0 +1,50 @@ +/* bam_sample.h -- group data by sample. + + Copyright (C) 2010 Broad Institute. + Copyright (C) 2016 Genome Research Ltd. + + Author: Heng Li , Petr Danecek + +Permission is hereby granted, free of charge, to any person obtaining a copy +of this software and associated documentation files (the "Software"), to deal +in the Software without restriction, including without limitation the rights +to use, copy, modify, merge, publish, distribute, sublicense, and/or sell +copies of the Software, and to permit persons to whom the Software is +furnished to do so, subject to the following conditions: + +The above copyright notice and this permission notice shall be included in +all copies or substantial portions of the Software. + +THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL +THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER +LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING +FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER +DEALINGS IN THE SOFTWARE. */ + +#ifndef BAM_SAMPLE_H +#define BAM_SAMPLE_H + +#include + +typedef struct _bam_smpl_t bam_smpl_t; + +bam_smpl_t *bam_smpl_init(void); + +int bam_smpl_add_samples(bam_smpl_t *bsmpl, char *list, int is_file); +int bam_smpl_add_readgroups(bam_smpl_t *bsmpl, char *list, int is_file); +void bam_smpl_ignore_readgroups(bam_smpl_t* bsmpl); + +// The above should be called only before bams are added. Returns the BAM id +// to be passed to bam_smpl_get_sample_id() later. It is safe to assume +// sequential numbering, starting from 0. +// +int bam_smpl_add_bam(bam_smpl_t *bsmpl, char *bam_hdr, const char *fname); + +const char **bam_smpl_get_samples(bam_smpl_t *bsmpl, int *nsmpl); +int bam_smpl_get_sample_id(bam_smpl_t *bsmpl, int bam_id, bam1_t *bam_rec); + +void bam_smpl_destroy(bam_smpl_t *bsmpl); + +#endif diff --git a/bcftools.h b/bcftools.h new file mode 100644 index 0000000..7d2d49f --- /dev/null +++ b/bcftools.h @@ -0,0 +1,73 @@ +/* bcftools.h -- utility function declarations. + + Copyright (C) 2013 Genome Research Ltd. + + Author: Petr Danecek + +Permission is hereby granted, free of charge, to any person obtaining a copy +of this software and associated documentation files (the "Software"), to deal +in the Software without restriction, including without limitation the rights +to use, copy, modify, merge, publish, distribute, sublicense, and/or sell +copies of the Software, and to permit persons to whom the Software is +furnished to do so, subject to the following conditions: + +The above copyright notice and this permission notice shall be included in +all copies or substantial portions of the Software. + +THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE +AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER +LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, +OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN +THE SOFTWARE. */ + +#ifndef BCFTOOLS_H +#define BCFTOOLS_H + +#include +#include +#include +#include + +#define FT_TAB_TEXT 0 // custom tab-delimited text file +#define FT_GZ 1 +#define FT_VCF 2 +#define FT_VCF_GZ (FT_GZ|FT_VCF) +#define FT_BCF (1<<2) +#define FT_BCF_GZ (FT_GZ|FT_BCF) +#define FT_STDIN (1<<3) + +char *bcftools_version(void); +void error(const char *format, ...) HTS_NORETURN; +void bcf_hdr_append_version(bcf_hdr_t *hdr, int argc, char **argv, const char *cmd); +const char *hts_bcf_wmode(int file_type); + +void *smalloc(size_t size); // safe malloc + +static inline char gt2iupac(char a, char b) +{ + static const char iupac[4][4] = { {'A','M','R','W'},{'M','C','S','Y'},{'R','S','G','K'},{'W','Y','K','T'} }; + if ( a>='a' ) a -= 'a' - 'A'; + if ( b>='a' ) b -= 'a' - 'A'; + if ( a=='A' ) a = 0; + else if ( a=='C' ) a = 1; + else if ( a=='G' ) a = 2; + else if ( a=='T' ) a = 3; + else return 'N'; + if ( b=='A' ) b = 0; + else if ( b=='C' ) b = 1; + else if ( b=='G' ) b = 2; + else if ( b=='T' ) b = 3; + else return 'N'; + return iupac[(int)a][(int)b]; +} + +static inline double phred_score(double prob) +{ + if ( prob==0 ) return 99; + prob = -4.3429*log(prob); + return prob>99 ? 99 : prob; +} + +#endif diff --git a/bin.c b/bin.c new file mode 100644 index 0000000..b558b20 --- /dev/null +++ b/bin.c @@ -0,0 +1,104 @@ +/* The MIT License + + Copyright (c) 2016 Genome Research Ltd. + + Author: Petr Danecek + + Permission is hereby granted, free of charge, to any person obtaining a copy + of this software and associated documentation files (the "Software"), to deal + in the Software without restriction, including without limitation the rights + to use, copy, modify, merge, publish, distribute, sublicense, and/or sell + copies of the Software, and to permit persons to whom the Software is + furnished to do so, subject to the following conditions: + + The above copyright notice and this permission notice shall be included in + all copies or substantial portions of the Software. + + THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR + IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, + FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE + AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER + LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, + OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN + THE SOFTWARE. + + */ + +#include +#include "bcftools.h" +#include "bin.h" + +struct _bin_t +{ + float *bins; + int nbins; +}; + +bin_t *bin_init(const char *list_def, float min, float max) +{ + bin_t *bin = (bin_t*) calloc(1,sizeof(bin_t)); + + // a comma indicates a list, otherwise a file + int is_file = strchr(list_def,',') ? 0 : 1; + int i, nlist; + char **list = hts_readlist(list_def, is_file, &nlist); + bin->nbins = nlist; + bin->bins = (float*) malloc(sizeof(float)*nlist); + for (i=0; ibins[i] = strtod(list[i],&tmp); + if ( !tmp ) error("Could not parse %s: %s\n", list_def, list[i]); + if ( min!=max && (bin->bins[i]bins[i]>max) ) + error("Expected values from the interval [%f,%f], found %s\n", list[i]); + free(list[i]); + } + free(list); + + if ( min!=max ) + { + // make sure we've got both boundaries: min,max. + assert( nlist>1 ); + float max_err = (bin->bins[1] - bin->bins[0])*1e-6; + if ( fabs(bin->bins[0] - min) > max_err ) + { + bin->bins = (float*) realloc(bin->bins, (++bin->nbins)*sizeof(float)); + memmove(bin->bins+1, bin->bins, sizeof(float)*(bin->nbins-1)); + bin->bins[0] = min; + } + if ( fabs(bin->bins[bin->nbins-1] - max) > max_err ) + { + bin->bins = (float*) realloc(bin->bins, (++bin->nbins)*sizeof(float)); + bin->bins[bin->nbins-1] = max; + } + } + return bin; +} + +void bin_destroy(bin_t *bin) +{ + free(bin->bins); + free(bin); +} + +int bin_get_size(bin_t *bin) { return bin->nbins; } + +float bin_get_value(bin_t *bin, int idx) { return bin->bins[idx]; } + +int bin_get_idx(bin_t *bin, float value) +{ + if ( bin->bins[bin->nbins-1] < value ) return bin->nbins-1; + + // Binary search in half-closed,half-open intervals [) + int imin = 0, imax = bin->nbins - 2; + while ( iminbins[i] ) imax = i - 1; + else if ( value > bin->bins[i] ) imin = i + 1; + else return i; + } + if ( bin->bins[imax] <= value ) return imax; + return imin - 1; +} + diff --git a/bin.h b/bin.h new file mode 100644 index 0000000..ab9e5b1 --- /dev/null +++ b/bin.h @@ -0,0 +1,65 @@ +/* The MIT License + + Copyright (c) 2016 Genome Research Ltd. + + Author: Petr Danecek + + Permission is hereby granted, free of charge, to any person obtaining a copy + of this software and associated documentation files (the "Software"), to deal + in the Software without restriction, including without limitation the rights + to use, copy, modify, merge, publish, distribute, sublicense, and/or sell + copies of the Software, and to permit persons to whom the Software is + furnished to do so, subject to the following conditions: + + The above copyright notice and this permission notice shall be included in + all copies or substantial portions of the Software. + + THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR + IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, + FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE + AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER + LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, + OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN + THE SOFTWARE. + + */ + +/* + Simple binning of float values into predefined bins +*/ + +#ifndef __BIN_H__ +#define __BIN_H__ + +#include + +typedef struct _bin_t bin_t; + +/* + * bin_init() - init bins + * @list: list of half-open intervals [). If the list does not contain commas, + * it is interpreted as a file name. + * @min,max: extreme values. This is for user convenience so that well-known + * extremes can be left out from the list. Ignored if min=max + */ +bin_t *bin_init(const char *list, float min, float max); +void bin_destroy(bin_t *bin); + +/* + * bin_get_size() - number of boundaries, subtract 1 to get the number of bins + */ +int bin_get_size(bin_t *bin); + +/* + bin_get_idx() - find the bin index which corresponds to the value (binary search) + Returns the bin index 0 <= idx <= size-2 or -1,size-1 for out of range values. + */ +int bin_get_idx(bin_t *bin, float value); + +/* + bin_get_value() - get the i-th boundary value, i=0,..,size-1 + */ +float bin_get_value(bin_t *bin, int ith); + +#endif + diff --git a/call.h b/call.h new file mode 100644 index 0000000..0d707a0 --- /dev/null +++ b/call.h @@ -0,0 +1,127 @@ +/* call.h -- variant calling declarations. + + Copyright (C) 2013-2014 Genome Research Ltd. + + Author: Petr Danecek + +Permission is hereby granted, free of charge, to any person obtaining a copy +of this software and associated documentation files (the "Software"), to deal +in the Software without restriction, including without limitation the rights +to use, copy, modify, merge, publish, distribute, sublicense, and/or sell +copies of the Software, and to permit persons to whom the Software is +furnished to do so, subject to the following conditions: + +The above copyright notice and this permission notice shall be included in +all copies or substantial portions of the Software. + +THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE +AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER +LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, +OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN +THE SOFTWARE. */ + +#ifndef __CALL_H__ +#define __CALL_H__ + +#include +#include +#include "vcmp.h" + +#define CALL_KEEPALT 1 +#define CALL_VARONLY (1<<1) +#define CALL_CONSTR_TRIO (1<<2) +#define CALL_CONSTR_ALLELES (1<<3) +// +// +#define CALL_FMT_GQ (1<<6) +#define CALL_FMT_GP (1<<7) + +#define FATHER 0 +#define MOTHER 1 +#define CHILD 2 +typedef struct +{ + char *name; + int sample[3]; // father, mother, child + int type; // see FTYPE_* definitions in mcall.c +} +family_t; + +typedef struct _ccall_t ccall_t; +typedef struct +{ + // mcall only + float *qsum; // QS(sum) values + int nqsum, npdg; + int *als_map, nals_map; // mapping from full set of alleles to trimmed set of alleles (old -> new) + int *pl_map, npl_map; // same as above for PLs, but reverse (new -> old) + char **als; // array to hold the trimmed set of alleles to appear on output + int nals; // size of the als array + family_t *fams; // list of families and samples for trio calling + int nfams, mfams; + int ntrio[5][5]; // possible trio genotype combinations and their counts; first idx: + uint16_t *trio[5][5]; // family type, second index: allele count (2-4, first two are unused) + double *GLs; + float *GPs; // FORMAT/GP: posterior probabilities + int32_t *GQs; // FORMAT/GQ: genotype qualities + int32_t *itmp; // temporary int array, used for new PLs with CALL_CONSTR_ALLELES + int n_itmp, nGPs; + vcmp_t *vcmp; + double trio_Pm_SNPs, trio_Pm_del, trio_Pm_ins; // P(mendelian) for trio calling, see mcall_call_trio_genotypes() + int32_t *ugts, *cgts; // unconstraind and constrained GTs + uint32_t output_tags; + char *prior_AN, *prior_AC; // reference panel AF tags (AF=AC/AN) + + // ccall only + double indel_frac, min_perm_p, min_lrt; + double prior_type, pref; + double ref_lk, lk_sum; + int ngrp1_samples, n_perm; + int nhets, ndiploid; + char *prior_file; + ccall_t *cdat; + + // shared + bcf_srs_t *srs; // BCF synced readers holding target alleles for CALL_CONSTR_ALLELES + bcf1_t *rec; + bcf_hdr_t *hdr; + uint32_t flag; // One or more of the CALL_* flags defined above + uint8_t *ploidy, all_diploid, unseen; + + double pl2p[256]; // PL to 10^(-PL/10) table + int32_t *PLs; // VCF PL likelihoods (rw) + int nPLs, mPLs, nac; + int32_t *gts, *ac; // GTs and AC (w) + double *pdg; // PLs converted to P(D|G) + float *anno16; int n16; // see anno[16] in bam2bcf.h + double theta; // prior +} +call_t; + +void error(const char *format, ...); + +/* + * call() - return -1 value on critical error; -2 to skip the site; or the number of non-reference + * alleles on success. + */ +int mcall(call_t *call, bcf1_t *rec); // multiallic and rare-variant calling model +int ccall(call_t *call, bcf1_t *rec); // the default consensus calling model +int qcall(call_t *call, bcf1_t *rec); // QCall output + +void mcall_init(call_t *call); +void ccall_init(call_t *call); +void qcall_init(call_t *call); + +void mcall_destroy(call_t *call); +void ccall_destroy(call_t *call); +void qcall_destroy(call_t *call); + +void call_init_pl2p(call_t *call); +uint32_t *call_trio_prep(int is_x, int is_son); + +void init_allele_trimming_maps(call_t *call, int als, int nals); +void mcall_trim_numberR(call_t *call, bcf1_t *rec, int nals, int nout_als, int out_als); + +#endif diff --git a/ccall.c b/ccall.c new file mode 100644 index 0000000..9f6958a --- /dev/null +++ b/ccall.c @@ -0,0 +1,337 @@ +/* ccall.c -- consensus variant calling. + + Copyright (C) 2013-2014 Genome Research Ltd. + Portions copyright (C) 2010 Broad Institute. + + Author: Petr Danecek + +Permission is hereby granted, free of charge, to any person obtaining a copy +of this software and associated documentation files (the "Software"), to deal +in the Software without restriction, including without limitation the rights +to use, copy, modify, merge, publish, distribute, sublicense, and/or sell +copies of the Software, and to permit persons to whom the Software is +furnished to do so, subject to the following conditions: + +The above copyright notice and this permission notice shall be included in +all copies or substantial portions of the Software. + +THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE +AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER +LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, +OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN +THE SOFTWARE. */ + +#include +#include +#include "call.h" +#include "kmin.h" +#include "prob1.h" + +// Most of the original -c calling was moved to bcftools as it was +// and its data structures were wrapped into the ccal_t to make it +// functional quickly. This is not the desired state. +struct _ccall_t +{ + bcf_p1aux_t *p1; +}; + +void ccall_init(call_t *call) +{ + call->cdat = (ccall_t*) calloc(1,sizeof(ccall_t)); + call_init_pl2p(call); + call->cdat->p1 = bcf_p1_init(bcf_hdr_nsamples(call->hdr), call->ploidy); + call->gts = (int*) calloc(bcf_hdr_nsamples(call->hdr)*2,sizeof(int)); // assuming at most diploid everywhere + call->nals_map = 5; + call->als_map = (int*) malloc(sizeof(int)*call->nals_map); + + bcf_hdr_append(call->hdr,"##FORMAT="); + if ( call->output_tags & CALL_FMT_GQ ) + { + bcf_hdr_append(call->hdr,"##FORMAT="); + call->GQs = (int32_t*) malloc(sizeof(int32_t)*bcf_hdr_nsamples(call->hdr)); + } + if ( call->output_tags & CALL_FMT_GP ) + error("Sorry, -f GP is not supported with -c\n"); + bcf_hdr_append(call->hdr,"##INFO="); + // Todo: groups not migrated to 'bcftools call' yet + bcf_hdr_append(call->hdr,"##INFO="); + bcf_hdr_append(call->hdr,"##INFO="); + bcf_hdr_append(call->hdr,"##INFO=\n"); + bcf_hdr_append(call->hdr,"##INFO=\n"); + bcf_hdr_append(call->hdr,"##INFO=\n"); + bcf_hdr_append(call->hdr,"##INFO=\n"); + bcf_hdr_append(call->hdr,"##INFO=\n"); + // bcf_hdr_append(call->hdr,); + // bcf_hdr_append(call->hdr,); + bcf_hdr_append(call->hdr,"##INFO="); + + return; +} +void ccall_destroy(call_t *call) +{ + free(call->itmp); + free(call->als_map); + free(call->gts); + free(call->anno16); + free(call->PLs); + free(call->GQs); + free(call->pdg); + bcf_p1_destroy(call->cdat->p1); + free(call->cdat); + return; +} + +// Inits P(D|G): convert PLs from log space, only two alleles (three PLs) are used. +// NB: The original samtools calling code uses pdgs in reverse order (AA comes +// first, RR last), while the -m calling model uses the canonical order. +static void set_pdg3(double *pl2p, int *PLs, double *pdg, int n_smpl, int n_gt) +{ + int i; + for (i=0; ip[0] = a->p[1] = a->p[2] = a->p[3] = 1.; + for (i=0; i<4; i++) a->d[i] = anno[i]; + a->depth = anno[0] + anno[1] + anno[2] + anno[3]; + a->is_tested = (anno[0] + anno[1] > 0 && anno[2] + anno[3] > 0); + if (a->depth == 0) return -1; + a->mq = (int)(sqrt((anno[9] + anno[11]) / a->depth) + .499); + kt_fisher_exact(anno[0], anno[1], anno[2], anno[3], &left, &right, &a->p[0]); + for (i = 1; i < 4; ++i) + a->p[i] = ttest(anno[0] + anno[1], anno[2] + anno[3], anno+4*i); + return 0; +} + +int test16(float *anno16, anno16_t *a) +{ + a->p[0] = a->p[1] = a->p[2] = a->p[3] = 1.; + a->d[0] = a->d[1] = a->d[2] = a->d[3] = 0.; + a->mq = a->depth = a->is_tested = 0; + return test16_core(anno16, a); +} +static int update_bcf1(call_t *call, bcf1_t *rec, const bcf_p1rst_t *pr, double em[10]) +{ + int has_I16, is_var; + float fq, r; + anno16_t a; + float tmpf[4], tmpi; + + bcf_get_info_float(call->hdr, rec, "I16", &call->anno16, &call->n16); + + has_I16 = test16(call->anno16, &a) >= 0? 1 : 0; + + // print EM + if (em[0] >= 0) + { + tmpf[0] = 1 - em[0]; + bcf_update_info_float(call->hdr, rec, "AF1", tmpf, 1); + } + if (em[4] >= 0 && em[4] <= 0.05) + { + tmpf[0] = em[3]; tmpf[1] = em[2]; tmpf[2] = em[1]; tmpf[3] = em[4]; + bcf_update_info_float(call->hdr, rec, "G3", tmpf, 3); + bcf_update_info_float(call->hdr, rec, "HWE", &tmpf[3], 1); + } + if (em[5] >= 0 && em[6] >= 0) + { + tmpf[0] = 1 - em[5]; tmpf[1] = 1 - em[6]; + bcf_update_info_float(call->hdr, rec, "AF2", tmpf, 2); + } + if (em[7] >= 0) + { + tmpf[0] = em[7]; + bcf_update_info_float(call->hdr, rec, "LRT", tmpf, 1); + } + if (em[8] >= 0) + { + tmpf[0] = em[8]; + bcf_update_info_float(call->hdr, rec, "LRT2", tmpf, 1); + } + + bcf_p1aux_t *p1 = call->cdat->p1; + if (p1->cons_llr > 0) + { + tmpi = p1->cons_llr; + bcf_update_info_int32(call->hdr, rec, "CLR", &tmpi, 1); + // todo: trio calling with -c + if (p1->cons_gt > 0) + { + char tmp[4]; + tmp[0] = p1->cons_gt&0xff; tmp[1] = p1->cons_gt>>8&0xff; tmp[2] = p1->cons_gt>>16&0xff; tmp[3] = 0; + bcf_update_info_string(call->hdr, rec, "UGT", tmp); + tmp[0] = p1->cons_gt>>32&0xff; tmp[1] = p1->cons_gt>>40&0xff; tmp[2] = p1->cons_gt>>48&0xff; + bcf_update_info_string(call->hdr, rec, "CGT", tmp); + } + } + is_var = (pr->p_ref < call->pref); + r = is_var? pr->p_ref : pr->p_var; + + bcf_update_info_int32(call->hdr, rec, "AC1", &pr->ac, 1); + int32_t dp[4]; dp[0] = call->anno16[0]; dp[1] = call->anno16[1]; dp[2] = call->anno16[2]; dp[3] = call->anno16[3]; + bcf_update_info_int32(call->hdr, rec, "DP4", dp, 4); + bcf_update_info_int32(call->hdr, rec, "MQ", &a.mq, 1); + + fq = pr->p_ref_folded < 0.5? -4.343 * log(pr->p_ref_folded) : 4.343 * log(pr->p_var_folded); + if (fq < -999) fq = -999; + if (fq > 999) fq = 999; + bcf_update_info_float(call->hdr, rec, "FQ", &fq, 1); + + assert( pr->cmp[0]<0 ); + // todo + // if (pr->cmp[0] >= 0.) { // two sample groups + // int i, q[3]; + // for (i = 1; i < 3; ++i) { + // double x = pr->cmp[i] + pr->cmp[0]/2.; + // q[i] = x == 0? 255 : (int)(-4.343 * log(x) + .499); + // if (q[i] > 255) q[i] = 255; + // } + // if (pr->perm_rank >= 0) ksprintf(&s, "PR=%d;", pr->perm_rank); + // + // ksprintf(&s, "PCHI2=%.3g;PC2=%d,%d;", q[1], q[2], pr->p_chi2); + // } + + if (has_I16 && a.is_tested) + { + int i; + for (i=0; i<4; i++) tmpf[i] = a.p[i]; + bcf_update_info_float(call->hdr, rec, "PV4", tmpf, 4); + } + bcf_update_info_int32(call->hdr, rec, "I16", NULL, 0); // remove I16 tag + bcf_update_info_int32(call->hdr, rec, "QS", NULL, 0); // remove QS tag + + rec->qual = r < 1e-100? 999 : -4.343 * log(r); + if (rec->qual > 999) rec->qual = 999; + + // Remove unused alleles + int nals_ori = rec->n_allele, nals = !is_var && !(call->flag & CALL_KEEPALT) ? 1 : pr->rank0 < 2? 2 : pr->rank0+1; + if ( call->flag & CALL_KEEPALT && call->unseen==nals-1 ) nals--; + + if ( nalsn_allele ) + { + bcf_update_alleles(call->hdr, rec, (const char**)rec->d.allele, nals); + + // Update PLs + int npls_src = call->nPLs / rec->n_sample, npls_dst = nals*(nals+1)/2; + int *pls_src = call->PLs - npls_src, *pls_dst = call->PLs - npls_dst; + int isample, i; + for (isample = 0; isample < rec->n_sample; isample++) + { + pls_src += npls_src; + pls_dst += npls_dst; + if ( !call->ploidy || call->ploidy[isample]==2 ) + { + for (i=0; ihdr, rec, "PL", call->PLs, npls_dst*rec->n_sample); + } + + // Call genotypes + int i; + for (i=0; in_sample; i++) + { + int x = ( is_var || call->output_tags & CALL_FMT_GQ ) ? bcf_p1_call_gt(p1, pr->f_exp, i, is_var) : 2; + int gt = x&3; + if ( !call->ploidy || call->ploidy[i]==2 ) + { + if ( gt==1 ) + { + call->gts[2*i] = bcf_gt_unphased(0); + call->gts[2*i+1] = bcf_gt_unphased(1); + } + else if ( gt==0 ) + { + call->gts[2*i] = bcf_gt_unphased(1); + call->gts[2*i+1] = bcf_gt_unphased(1); + } + else + { + call->gts[2*i] = bcf_gt_unphased(0); + call->gts[2*i+1] = bcf_gt_unphased(0); + } + if ( call->output_tags & CALL_FMT_GQ ) call->GQs[i] = x>>2; + } + else + { + if ( gt==0 ) call->gts[2*i] = bcf_gt_unphased(1); + else call->gts[2*i] = bcf_gt_unphased(0); + call->gts[2*i+1] = bcf_int32_vector_end; + if ( call->output_tags & CALL_FMT_GQ ) call->GQs[i] = bcf_int32_missing; + } + } + bcf_update_genotypes(call->hdr, rec, call->gts, rec->n_sample*2); + if ( call->output_tags & CALL_FMT_GQ ) + bcf_update_format_int32(call->hdr, rec, "GQ", call->GQs, rec->n_sample); + + // trim Number=R tags + int out_als = 0; + for (i=0; ihdr); + + // Get the genotype likelihoods + int nals = rec->n_allele; + call->nPLs = bcf_get_format_int32(call->hdr, rec, "PL", &call->PLs, &call->mPLs); + if ( call->nPLs!=nsmpl*nals*(nals+1)/2 && call->nPLs!=nsmpl*nals ) // diploid+haploid or haploid only + error("Wrong number of PL fields? nals=%d npl=%d\n", nals,call->nPLs); + + // Convert PLs to probabilities, only first two alleles are considered + int ngts = nals*(nals+1)/2; + hts_expand(double, 3*nsmpl, call->npdg, call->pdg); + set_pdg3(call->pl2p, call->PLs, call->pdg, nsmpl, ngts); + + double em[10] = {-1.,-1.,-1.,-1.,-1.,-1.,-1.,-1.,-1.,-1.}; + int ret = bcf_em1(call, rec, call->ngrp1_samples, 0x1ff, em); + + bcf_p1rst_t pr; + int do_contrast = (em[7] >= 0 && em[7] < call->min_lrt) ? 1 : 0; + ret = bcf_p1_cal(call, rec, do_contrast, call->cdat->p1, &pr); + if (pr.p_ref >= call->pref && (call->flag & CALL_VARONLY)) return 0; + if (ret >= 0) ret = update_bcf1(call, rec, &pr, em); + return ret; +} + diff --git a/consensus.c b/consensus.c new file mode 100644 index 0000000..4fccc4f --- /dev/null +++ b/consensus.c @@ -0,0 +1,688 @@ +/* The MIT License + + Copyright (c) 2014 Genome Research Ltd. + + Author: Petr Danecek + + Permission is hereby granted, free of charge, to any person obtaining a copy + of this software and associated documentation files (the "Software"), to deal + in the Software without restriction, including without limitation the rights + to use, copy, modify, merge, publish, distribute, sublicense, and/or sell + copies of the Software, and to permit persons to whom the Software is + furnished to do so, subject to the following conditions: + + The above copyright notice and this permission notice shall be included in + all copies or substantial portions of the Software. + + THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR + IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, + FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE + AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER + LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, + OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN + THE SOFTWARE. + + */ + +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include "regidx.h" +#include "bcftools.h" +#include "rbuf.h" + +typedef struct +{ + int num; // number of ungapped blocks in this chain + int *block_lengths; // length of the ungapped blocks in this chain + int *ref_gaps; // length of the gaps on the reference sequence between blocks + int *alt_gaps; // length of the gaps on the alternative sequence between blocks + int ori_pos; + int ref_last_block_ori; // start position on the reference sequence of the following ungapped block (0-based) + int alt_last_block_ori; // start position on the alternative sequence of the following ungapped block (0-based) +} +chain_t; + + +typedef struct +{ + kstring_t fa_buf; // buffered reference sequence + int fa_ori_pos; // start position of the fa_buffer (wrt original sequence) + int fa_frz_pos; // protected position to avoid conflicting variants (last pos for SNPs/ins) + int fa_mod_off; // position difference of fa_frz_pos in the ori and modified sequence (ins positive) + int fa_end_pos; // region's end position in the original sequence + int fa_length; // region's length in the original sequence (in case end_pos not provided in the FASTA header) + int fa_case; // output upper case or lower case? + int fa_src_pos; // last genomic coordinate read from the input fasta (0-based) + + rbuf_t vcf_rbuf; + bcf1_t **vcf_buf; + int nvcf_buf, rid; + + regidx_t *mask; + regitr_t *itr; + + int chain_id; // chain_id, to provide a unique ID to each chain in the chain output + chain_t *chain; // chain structure to store the sequence of ungapped blocks between the ref and alt sequences + // Note that the chain is re-initialised for each chromosome/seq_region + + bcf_srs_t *files; + bcf_hdr_t *hdr; + FILE *fp_out; + FILE *fp_chain; + char **argv; + int argc, output_iupac, haplotype, isample; + char *fname, *ref_fname, *sample, *output_fname, *mask_fname, *chain_fname; +} +args_t; + +static chain_t* init_chain(chain_t *chain, int ref_ori_pos) +{ +// fprintf(stderr, "init_chain(*chain, ref_ori_pos=%d)\n", ref_ori_pos); + chain = (chain_t*) calloc(1,sizeof(chain_t)); + chain->num = 0; + chain->block_lengths = NULL; + chain->ref_gaps = NULL; + chain->alt_gaps = NULL; + chain->ori_pos = ref_ori_pos; + chain->ref_last_block_ori = ref_ori_pos; + chain->alt_last_block_ori = ref_ori_pos; + return chain; +} + +static void destroy_chain(args_t *args) +{ + chain_t *chain = args->chain; + free(chain->ref_gaps); + free(chain->alt_gaps); + free(chain->block_lengths); + free(chain); + chain = NULL; +} + +static void print_chain(args_t *args) +{ + /* + Example chain format (see: https://genome.ucsc.edu/goldenPath/help/chain.html): + chain 1 500 + 480 500 1 501 + 480 501 1 + 12 3 1 + 1 0 3 + 484 + + chain line is: + - chain + - score (sum of the length of ungapped block in this case) + - ref_seqname (from the fasta header, parsed by htslib) + - ref_seqlength (from the fasta header) + - ref_strand (+ or -; always + for bcf-consensus) + - ref_start (as defined in the fasta header) + - ref_end (as defined in the fasta header) + - alt_seqname (same as ref_seqname as bcf-consensus only considers SNPs and indels) + - alt_seqlength (adjusted to match the length of the alt sequence) + - alt_strand (+ or -; always + for bcf-consensus) + - alt_start (same as ref_start, as no edits are recorded/applied before that position) + - alt_end (adjusted to match the length of the alt sequence) + - chain_num (just an auto-increment id) + + the other (sorted) lines are: + - length of the ungapped alignment block + - gap on the ref sequence between this and the next block (all but the last line) + - gap on the alt sequence between this and the next block (all but the last line) + */ + chain_t *chain = args->chain; + int n = chain->num; + int ref_end_pos = args->fa_length + chain->ori_pos; + int last_block_size = ref_end_pos - chain->ref_last_block_ori; + int alt_end_pos = chain->alt_last_block_ori + last_block_size; + int score = 0; + for (n=0; nnum; n++) { + score += chain->block_lengths[n]; + } + score += last_block_size; + fprintf(args->fp_chain, "chain %d %s %d + %d %d %s %d + %d %d %d\n", score, bcf_hdr_id2name(args->hdr,args->rid), ref_end_pos, chain->ori_pos, ref_end_pos, bcf_hdr_id2name(args->hdr,args->rid), alt_end_pos, chain->ori_pos, alt_end_pos, ++args->chain_id); + for (n=0; nnum; n++) { + fprintf(args->fp_chain, "%d %d %d\n", chain->block_lengths[n], chain->ref_gaps[n], chain->alt_gaps[n]); + } + fprintf(args->fp_chain, "%d\n\n", last_block_size); +} + +static void push_chain_gap(chain_t *chain, int ref_start, int ref_len, int alt_start, int alt_len) +{ +// fprintf(stderr, "push_chain_gap(*chain, ref_start=%d, ref_len=%d, alt_start=%d, alt_len=%d)\n", ref_start, ref_len, alt_start, alt_len); + int num = chain->num; + + if (ref_start <= chain->ref_last_block_ori) { + // In case this variant is back-to-back with the previous one + chain->ref_last_block_ori = ref_start + ref_len; + chain->alt_last_block_ori = alt_start + alt_len; + chain->ref_gaps[num-1] += ref_len; + chain->alt_gaps[num-1] += alt_len; + + } else { + // Extend the ungapped blocks, store the gap length + chain->block_lengths = (int*) realloc(chain->block_lengths, (num + 1) * sizeof(int)); + chain->ref_gaps = (int*) realloc(chain->ref_gaps, (num + 1) * sizeof(int)); + chain->alt_gaps = (int*) realloc(chain->alt_gaps, (num + 1) * sizeof(int)); + chain->block_lengths[num] = ref_start - chain->ref_last_block_ori; + chain->ref_gaps[num] = ref_len; + chain->alt_gaps[num] = alt_len; + // Update the start positions of the next block + chain->ref_last_block_ori = ref_start + ref_len; + chain->alt_last_block_ori = alt_start + alt_len; + // Increment the number of ungapped blocks + chain->num++; + } +} + +static void init_data(args_t *args) +{ + args->files = bcf_sr_init(); + args->files->require_index = 1; + if ( !bcf_sr_add_reader(args->files,args->fname) ) error("Failed to open %s: %s\n", args->fname, bcf_sr_strerror(args->files->errnum)); + args->hdr = args->files->readers[0].header; + args->isample = -1; + if ( args->sample ) + { + args->isample = bcf_hdr_id2int(args->hdr,BCF_DT_SAMPLE,args->sample); + if ( args->isample<0 ) error("No such sample: %s\n", args->sample); + } + if ( args->haplotype && args->isample<0 ) + { + if ( bcf_hdr_nsamples(args->hdr) > 1 ) error("The --sample option is expected with --haplotype\n"); + args->isample = 0; + } + if ( args->mask_fname ) + { + args->mask = regidx_init(args->mask_fname,NULL,NULL,0,NULL); + if ( !args->mask ) error("Failed to initialize mask regions\n"); + args->itr = regitr_init(args->mask); + } + // In case we want to store the chains + if ( args->chain_fname ) + { + args->fp_chain = fopen(args->chain_fname,"w"); + if ( ! args->fp_chain ) error("Failed to create %s: %s\n", args->chain_fname, strerror(errno)); + args->chain_id = 0; + } + rbuf_init(&args->vcf_rbuf, 100); + args->vcf_buf = (bcf1_t**) calloc(args->vcf_rbuf.m, sizeof(bcf1_t*)); + if ( args->output_fname ) { + args->fp_out = fopen(args->output_fname,"w"); + if ( ! args->fp_out ) error("Failed to create %s: %s\n", args->output_fname, strerror(errno)); + } + else args->fp_out = stdout; +} + +static void destroy_data(args_t *args) +{ + bcf_sr_destroy(args->files); + int i; + for (i=0; ivcf_rbuf.m; i++) + if ( args->vcf_buf[i] ) bcf_destroy1(args->vcf_buf[i]); + free(args->vcf_buf); + free(args->fa_buf.s); + if ( args->mask ) regidx_destroy(args->mask); + if ( args->itr ) regitr_destroy(args->itr); + if ( args->chain_fname ) + if ( fclose(args->fp_chain) ) error("Close failed: %s\n", args->chain_fname); + if ( fclose(args->fp_out) ) error("Close failed: %s\n", args->output_fname); +} + +static void init_region(args_t *args, char *line) +{ + char *ss, *se = line; + while ( *se && !isspace(*se) && *se!=':' ) se++; + int from = 0, to = 0; + char tmp, *tmp_ptr = NULL; + if ( *se ) + { + tmp = *se; *se = 0; tmp_ptr = se; + ss = ++se; + from = strtol(ss,&se,10); + if ( ss==se || !*se || *se!='-' ) from = 0; + else + { + from--; + ss = ++se; + to = strtol(ss,&se,10); + if ( ss==se || (*se && !isspace(*se)) ) { from = 0; to = 0; } + else to--; + } + } + args->rid = bcf_hdr_name2id(args->hdr,line); + if ( args->rid<0 ) fprintf(stderr,"Warning: Sequence \"%s\" not in %s\n", line,args->fname); + args->fa_buf.l = 0; + args->fa_length = 0; + args->fa_end_pos = to; + args->fa_ori_pos = from; + args->fa_src_pos = from; + args->fa_mod_off = 0; + args->fa_frz_pos = -1; + args->fa_case = -1; + args->vcf_rbuf.n = 0; + bcf_sr_seek(args->files,line,args->fa_ori_pos); + if ( tmp_ptr ) *tmp_ptr = tmp; + fprintf(args->fp_out,">%s\n",line); + if (args->chain_fname ) + { + args->chain = init_chain(args->chain, args->fa_ori_pos); + } else { + args->chain = NULL; + } +} + +static bcf1_t **next_vcf_line(args_t *args) +{ + if ( args->vcf_rbuf.n ) + { + int i = rbuf_shift(&args->vcf_rbuf); + return &args->vcf_buf[i]; + } + else if ( bcf_sr_next_line(args->files) ) + return &args->files->readers[0].buffer[0]; + + return NULL; +} +static void unread_vcf_line(args_t *args, bcf1_t **rec_ptr) +{ + bcf1_t *rec = *rec_ptr; + if ( args->vcf_rbuf.n >= args->vcf_rbuf.m ) + error("FIXME: too many overlapping records near %s:%d\n", bcf_seqname(args->hdr,rec),rec->pos+1); + + // Insert the new record in the buffer. The line would be overwritten in + // the next bcf_sr_next_line call, therefore we need to swap it with an + // unused one + int i = rbuf_append(&args->vcf_rbuf); + if ( !args->vcf_buf[i] ) args->vcf_buf[i] = bcf_init1(); + bcf1_t *tmp = rec; *rec_ptr = args->vcf_buf[i]; args->vcf_buf[i] = tmp; +} +static void flush_fa_buffer(args_t *args, int len) +{ + if ( !args->fa_buf.l ) return; + + int nwr = 0; + while ( nwr + 60 <= args->fa_buf.l ) + { + if ( fwrite(args->fa_buf.s+nwr,1,60,args->fp_out) != 60 ) error("Could not write: %s\n", args->output_fname); + if ( fwrite("\n",1,1,args->fp_out) != 1 ) error("Could not write: %s\n", args->output_fname); + nwr += 60; + } + if ( nwr ) + args->fa_ori_pos += nwr; + + if ( len ) + { + // not finished on this chr yet and the buffer cannot be emptied completely + if ( nwr && nwr < args->fa_buf.l ) + memmove(args->fa_buf.s,args->fa_buf.s+nwr,args->fa_buf.l-nwr); + args->fa_buf.l -= nwr; + return; + } + + // empty the whole buffer + if ( nwr == args->fa_buf.l ) { args->fa_buf.l = 0; return; } + + if ( fwrite(args->fa_buf.s+nwr,1,args->fa_buf.l - nwr,args->fp_out) != args->fa_buf.l - nwr ) error("Could not write: %s\n", args->output_fname); + if ( fwrite("\n",1,1,args->fp_out) != 1 ) error("Could not write: %s\n", args->output_fname); + + args->fa_ori_pos += args->fa_buf.l - nwr - args->fa_mod_off; + args->fa_mod_off = 0; + args->fa_buf.l = 0; +} +static void apply_variant(args_t *args, bcf1_t *rec) +{ + if ( rec->n_allele==1 ) return; + + if ( rec->pos <= args->fa_frz_pos ) + { + fprintf(stderr,"The site %s:%d overlaps with another variant, skipping...\n", bcf_seqname(args->hdr,rec),rec->pos+1); + return; + } + if ( args->mask ) + { + char *chr = (char*)bcf_hdr_id2name(args->hdr,args->rid); + int start = rec->pos; + int end = rec->pos + rec->rlen - 1; + if ( regidx_overlap(args->mask, chr,start,end,NULL) ) return; + } + + int i, ialt = 1; + if ( args->isample >= 0 ) + { + bcf_fmt_t *fmt = bcf_get_fmt(args->hdr, rec, "GT"); + if ( !fmt ) return; + if ( args->haplotype ) + { + if ( args->haplotype > fmt->n ) error("Can't apply %d-th haplotype at %s:%d\n", args->haplotype,bcf_seqname(args->hdr,rec),rec->pos+1); + uint8_t *ignore, *ptr = fmt->p + fmt->size*args->isample + args->haplotype - 1; + ialt = bcf_dec_int1(ptr, fmt->type, &ignore); + if ( bcf_gt_is_missing(ialt) || ialt==bcf_int32_vector_end ) return; + ialt = bcf_gt_allele(ialt); + } + else if ( args->output_iupac ) + { + uint8_t *ignore, *ptr = fmt->p + fmt->size*args->isample; + ialt = bcf_dec_int1(ptr, fmt->type, &ignore); + if ( bcf_gt_is_missing(ialt) || ialt==bcf_int32_vector_end ) return; + ialt = bcf_gt_allele(ialt); + + int jalt; + if ( fmt->n>1 ) + { + ptr = fmt->p + fmt->size*args->isample + 1; + jalt = bcf_dec_int1(ptr, fmt->type, &ignore); + if ( bcf_gt_is_missing(jalt) || jalt==bcf_int32_vector_end ) jalt = ialt; + else jalt = bcf_gt_allele(jalt); + } + else jalt = ialt; + if ( rec->n_allele <= ialt || rec->n_allele <= jalt ) error("Broken VCF, too few alts at %s:%d\n", bcf_seqname(args->hdr,rec),rec->pos+1); + if ( ialt!=jalt && !rec->d.allele[ialt][1] && !rec->d.allele[jalt][1] ) // is this a het snp? + { + char ial = rec->d.allele[ialt][0]; + char jal = rec->d.allele[jalt][0]; + rec->d.allele[ialt][0] = gt2iupac(ial,jal); + } + } + else + { + for (i=0; in; i++) + { + uint8_t *ignore, *ptr = fmt->p + fmt->size*args->isample + i; + ialt = bcf_dec_int1(ptr, fmt->type, &ignore); + if ( bcf_gt_is_missing(ialt) || ialt==bcf_int32_vector_end ) return; + ialt = bcf_gt_allele(ialt); + if ( ialt ) break; + } + } + if ( !ialt ) return; // ref allele + if ( rec->n_allele <= ialt ) error("Broken VCF, too few alts at %s:%d\n", bcf_seqname(args->hdr,rec),rec->pos+1); + } + else if ( args->output_iupac && !rec->d.allele[0][1] && !rec->d.allele[1][1] ) + { + char ial = rec->d.allele[0][0]; + char jal = rec->d.allele[1][0]; + rec->d.allele[1][0] = gt2iupac(ial,jal); + } + + int len_diff = 0, alen = 0; + int idx = rec->pos - args->fa_ori_pos + args->fa_mod_off; + if ( idx<0 ) + { + fprintf(stderr,"Warning: ignoring overlapping variant starting at %s:%d\n", bcf_seqname(args->hdr,rec),rec->pos+1); + return; + } + if ( rec->rlen > args->fa_buf.l - idx ) + { + rec->rlen = args->fa_buf.l - idx; + alen = strlen(rec->d.allele[ialt]); + if ( alen > rec->rlen ) + { + rec->d.allele[ialt][rec->rlen] = 0; + fprintf(stderr,"Warning: trimming variant starting at %s:%d\n", bcf_seqname(args->hdr,rec),rec->pos+1); + } + } + if ( idx>=args->fa_buf.l ) + error("FIXME: %s:%d .. idx=%d, ori_pos=%d, len=%d, off=%d\n",bcf_seqname(args->hdr,rec),rec->pos+1,idx,args->fa_ori_pos,args->fa_buf.l,args->fa_mod_off); + + // sanity check the reference base + if ( rec->d.allele[ialt][0]=='<' ) + { + if ( strcasecmp(rec->d.allele[ialt], "") ) + error("Symbolic alleles other than are currently not supported: %s at %s:%d\n",rec->d.allele[ialt],bcf_seqname(args->hdr,rec),rec->pos+1); + assert( rec->d.allele[0][1]==0 ); // todo: for now expecting strlen(REF) = 1 + len_diff = 1-rec->rlen; + rec->d.allele[ialt] = rec->d.allele[0]; // according to VCF spec, REF must precede the event + alen = strlen(rec->d.allele[ialt]); + } + else if ( strncasecmp(rec->d.allele[0],args->fa_buf.s+idx,rec->rlen) ) + { + // fprintf(stderr,"%d .. [%s], idx=%d ori=%d off=%d\n",args->fa_ori_pos,args->fa_buf.s,idx,args->fa_ori_pos,args->fa_mod_off); + char tmp = 0; + if ( args->fa_buf.l - idx > rec->rlen ) + { + tmp = args->fa_buf.s[idx+rec->rlen]; + args->fa_buf.s[idx+rec->rlen] = 0; + } + error( + "The fasta sequence does not match the REF allele at %s:%d:\n" + " .vcf: [%s]\n" + " .vcf: [%s] <- (ALT)\n" + " .fa: [%s]%c%s\n", + bcf_seqname(args->hdr,rec),rec->pos+1, rec->d.allele[0], rec->d.allele[ialt], args->fa_buf.s+idx, + tmp?tmp:' ',tmp?args->fa_buf.s+idx+rec->rlen+1:"" + ); + } + else + { + alen = strlen(rec->d.allele[ialt]); + len_diff = alen - rec->rlen; + } + + if ( args->fa_case ) + for (i=0; id.allele[ialt][i] = toupper(rec->d.allele[ialt][i]); + else + for (i=0; id.allele[ialt][i] = tolower(rec->d.allele[ialt][i]); + + if ( len_diff <= 0 ) + { + // deletion or same size event + for (i=0; ifa_buf.s[idx+i] = rec->d.allele[ialt][i]; + if ( len_diff ) + memmove(args->fa_buf.s+idx+alen,args->fa_buf.s+idx+rec->rlen,args->fa_buf.l-idx-rec->rlen); + } + else + { + // insertion + ks_resize(&args->fa_buf, args->fa_buf.l + len_diff); + memmove(args->fa_buf.s + idx + rec->rlen + len_diff, args->fa_buf.s + idx + rec->rlen, args->fa_buf.l - idx - rec->rlen); + for (i=0; ifa_buf.s[idx+i] = rec->d.allele[ialt][i]; + } + if (args->chain && len_diff != 0) + { + // If first nucleotide of both REF and ALT are the same... (indels typically include the nucleotide before the variant) + if ( strncasecmp(rec->d.allele[0],rec->d.allele[ialt],1) == 0) + { + // ...extend the block by 1 bp: start is 1 bp further and alleles are 1 bp shorter + push_chain_gap(args->chain, rec->pos + 1, rec->rlen - 1, rec->pos + 1 + args->fa_mod_off, alen - 1); + } + else + { + // otherwise, just the coordinates of the variant as given + push_chain_gap(args->chain, rec->pos, rec->rlen, rec->pos + args->fa_mod_off, alen); + } + } + args->fa_buf.l += len_diff; + args->fa_mod_off += len_diff; + args->fa_frz_pos = rec->pos + rec->rlen - 1; +} + + +static void mask_region(args_t *args, char *seq, int len) +{ + char *chr = (char*)bcf_hdr_id2name(args->hdr,args->rid); + int start = args->fa_src_pos - len; + int end = args->fa_src_pos; + + if ( !regidx_overlap(args->mask, chr,start,end, args->itr) ) return; + + int idx_start, idx_end, i; + while ( regitr_overlap(args->itr) ) + { + idx_start = args->itr->beg - start; + idx_end = args->itr->end - start; + if ( idx_start < 0 ) idx_start = 0; + if ( idx_end >= len ) idx_end = len - 1; + for (i=idx_start; i<=idx_end; i++) seq[i] = 'N'; + } +} + +static void consensus(args_t *args) +{ + htsFile *fasta = hts_open(args->ref_fname, "rb"); + if ( !fasta ) error("Error reading %s\n", args->ref_fname); + kstring_t str = {0,0,0}; + while ( hts_getline(fasta, KS_SEP_LINE, &str) > 0 ) + { + if ( str.s[0]=='>' ) + { + // new sequence encountered, apply all cached variants + while ( args->vcf_rbuf.n ) + { + if (args->chain) { + print_chain(args); + destroy_chain(args); + } + bcf1_t *rec = args->vcf_buf[args->vcf_rbuf.f]; + if ( rec->rid!=args->rid || ( args->fa_end_pos && rec->pos > args->fa_end_pos ) ) break; + int i = rbuf_shift(&args->vcf_rbuf); + apply_variant(args, args->vcf_buf[i]); + } + flush_fa_buffer(args, 0); + init_region(args, str.s+1); + continue; + } + args->fa_length += str.l; + args->fa_src_pos += str.l; + + // determine if uppercase or lowercase is used in this fasta file + if ( args->fa_case==-1 ) args->fa_case = toupper(str.s[0])==str.s[0] ? 1 : 0; + + if ( args->mask && args->rid>=0) mask_region(args, str.s, str.l); + kputs(str.s, &args->fa_buf); + + bcf1_t **rec_ptr = NULL; + while ( args->rid>=0 && (rec_ptr = next_vcf_line(args)) ) + { + bcf1_t *rec = *rec_ptr; + + // still the same chr and the same region? if not, fasta buf can be flushed + if ( rec->rid!=args->rid || ( args->fa_end_pos && rec->pos > args->fa_end_pos ) ) + { + // save the vcf record until next time and flush + unread_vcf_line(args, rec_ptr); + rec_ptr = NULL; + break; + } + + // is the vcf record well beyond cached fasta buffer? if yes, the buf can be flushed + if ( args->fa_ori_pos + args->fa_buf.l - args->fa_mod_off <= rec->pos ) + { + unread_vcf_line(args, rec_ptr); + rec_ptr = NULL; + break; + } + + // is the cached fasta buffer full enough? if not, read more fasta, no flushing + if ( args->fa_ori_pos + args->fa_buf.l - args->fa_mod_off < rec->pos + rec->rlen ) + { + unread_vcf_line(args, rec_ptr); + break; + } + apply_variant(args, rec); + } + if ( !rec_ptr ) flush_fa_buffer(args, 60); + } + bcf1_t **rec_ptr = NULL; + while ( args->rid>=0 && (rec_ptr = next_vcf_line(args)) ) + { + bcf1_t *rec = *rec_ptr; + if ( rec->rid!=args->rid ) break; + if ( args->fa_end_pos && rec->pos > args->fa_end_pos ) break; + if ( args->fa_ori_pos + args->fa_buf.l - args->fa_mod_off <= rec->pos ) break; + apply_variant(args, rec); + } + if (args->chain) + { + print_chain(args); + destroy_chain(args); + } + flush_fa_buffer(args, 0); + hts_close(fasta); + free(str.s); +} + +static void usage(args_t *args) +{ + fprintf(stderr, "\n"); + fprintf(stderr, "About: Create consensus sequence by applying VCF variants to a reference fasta\n"); + fprintf(stderr, " file. By default, the program will apply all ALT variants. Using the\n"); + fprintf(stderr, " --sample (and, optionally, --haplotype) option will apply genotype\n"); + fprintf(stderr, " (or haplotype) calls from FORMAT/GT. The program ignores allelic depth\n"); + fprintf(stderr, " information, such as INFO/AD or FORMAT/AD.\n"); + fprintf(stderr, "Usage: bcftools consensus [OPTIONS] \n"); + fprintf(stderr, "Options:\n"); + fprintf(stderr, " -f, --fasta-ref reference sequence in fasta format\n"); + fprintf(stderr, " -H, --haplotype <1|2> apply variants for the given haplotype\n"); + fprintf(stderr, " -i, --iupac-codes output variants in the form of IUPAC ambiguity codes\n"); + fprintf(stderr, " -m, --mask replace regions with N\n"); + fprintf(stderr, " -o, --output write output to a file [standard output]\n"); + fprintf(stderr, " -c, --chain write a chain file for liftover\n"); + fprintf(stderr, " -s, --sample apply variants of the given sample\n"); + fprintf(stderr, "Examples:\n"); + fprintf(stderr, " # Get the consensus for one region. The fasta header lines are then expected\n"); + fprintf(stderr, " # in the form \">chr:from-to\".\n"); + fprintf(stderr, " samtools faidx ref.fa 8:11870-11890 | bcftools consensus in.vcf.gz > out.fa\n"); + fprintf(stderr, "\n"); + exit(1); +} + +int main_consensus(int argc, char *argv[]) +{ + args_t *args = (args_t*) calloc(1,sizeof(args_t)); + args->argc = argc; args->argv = argv; + + static struct option loptions[] = + { + {"sample",1,0,'s'}, + {"iupac-codes",0,0,'i'}, + {"haplotype",1,0,'H'}, + {"output",1,0,'o'}, + {"fasta-ref",1,0,'f'}, + {"mask",1,0,'m'}, + {"chain",1,0,'c'}, + {0,0,0,0} + }; + int c; + while ((c = getopt_long(argc, argv, "h?s:1iH:f:o:m:c:",loptions,NULL)) >= 0) + { + switch (c) + { + case 's': args->sample = optarg; break; + case 'o': args->output_fname = optarg; break; + case 'i': args->output_iupac = 1; break; + case 'f': args->ref_fname = optarg; break; + case 'm': args->mask_fname = optarg; break; + case 'c': args->chain_fname = optarg; break; + case 'H': + args->haplotype = optarg[0] - '0'; + if ( args->haplotype <=0 ) error("Expected positive integer with --haplotype\n"); + break; + default: usage(args); break; + } + } + if ( optind>=argc ) usage(args); + args->fname = argv[optind]; + + if ( !args->ref_fname && !isatty(fileno((FILE *)stdin)) ) args->ref_fname = "-"; + if ( !args->ref_fname ) usage(args); + + init_data(args); + consensus(args); + destroy_data(args); + free(args); + + return 0; +} + + diff --git a/convert.c b/convert.c new file mode 100644 index 0000000..05dce01 --- /dev/null +++ b/convert.c @@ -0,0 +1,1376 @@ +/* convert.c -- functions for converting between VCF/BCF and related formats. + + Copyright (C) 2013-2017 Genome Research Ltd. + + Author: Petr Danecek + +Permission is hereby granted, free of charge, to any person obtaining a copy +of this software and associated documentation files (the "Software"), to deal +in the Software without restriction, including without limitation the rights +to use, copy, modify, merge, publish, distribute, sublicense, and/or sell +copies of the Software, and to permit persons to whom the Software is +furnished to do so, subject to the following conditions: + +The above copyright notice and this permission notice shall be included in +all copies or substantial portions of the Software. + +THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE +AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER +LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, +OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN +THE SOFTWARE. */ + +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include "bcftools.h" +#include "convert.h" + +#define T_CHROM 1 +#define T_POS 2 +#define T_ID 3 +#define T_REF 4 +#define T_ALT 5 +#define T_QUAL 6 +#define T_FILTER 7 +#define T_INFO 8 +#define T_FORMAT 9 +#define T_SAMPLE 10 +#define T_SEP 11 +#define T_IS_TS 12 +#define T_TYPE 13 +#define T_MASK 14 +#define T_GT 15 +#define T_TGT 16 +#define T_LINE 17 +#define T_CHROM_POS_ID 18 // not publicly advertised +#define T_GT_TO_PROB3 19 // not publicly advertised +#define T_PL_TO_PROB3 20 // not publicly advertised +#define T_GP_TO_PROB3 21 // not publicly advertised +#define T_FIRST_ALT 22 // not publicly advertised +#define T_IUPAC_GT 23 +#define T_GT_TO_HAP 24 // not publicly advertised +#define T_GT_TO_HAP2 25 // not publicly advertised +#define T_TBCSQ 26 +#define T_END 27 +#define T_POS0 28 +#define T_END0 29 + +typedef struct _fmt_t +{ + int type, id, is_gt_field, ready, subscript; + char *key; + bcf_fmt_t *fmt; + void *usr; // user data (optional) + void (*handler)(convert_t *, bcf1_t *, struct _fmt_t *, int, kstring_t *); + void (*destroy)(void*); // clean user data (optional) +} +fmt_t; + +struct _convert_t +{ + fmt_t *fmt; + int nfmt, mfmt; + int nsamples, *samples; + bcf_hdr_t *header; + int max_unpack; + char *format_str; + bcf_srs_t *readers; // required only for %MASK + int nreaders; + void *dat; + int ndat; + char *undef_info_tag; + int allow_undef_tags; +}; + +typedef struct +{ + kstring_t hap1,hap2; + char **str; + int n, m; +} +bcsq_t; + +static void process_chrom(convert_t *convert, bcf1_t *line, fmt_t *fmt, int isample, kstring_t *str) { kputs(convert->header->id[BCF_DT_CTG][line->rid].key, str); } +static void process_pos(convert_t *convert, bcf1_t *line, fmt_t *fmt, int isample, kstring_t *str) { kputw(line->pos+1, str); } +static void process_pos0(convert_t *convert, bcf1_t *line, fmt_t *fmt, int isample, kstring_t *str) { kputw(line->pos, str); } +static void process_end(convert_t *convert, bcf1_t *line, fmt_t *fmt, int isample, kstring_t *str) { kputw(line->pos+line->rlen, str); } +static void process_end0(convert_t *convert, bcf1_t *line, fmt_t *fmt, int isample, kstring_t *str) { kputw(line->pos+line->rlen-1, str); } +static void process_id(convert_t *convert, bcf1_t *line, fmt_t *fmt, int isample, kstring_t *str) { kputs(line->d.id, str); } +static void process_ref(convert_t *convert, bcf1_t *line, fmt_t *fmt, int isample, kstring_t *str) { kputs(line->d.allele[0], str); } +static void process_alt(convert_t *convert, bcf1_t *line, fmt_t *fmt, int isample, kstring_t *str) +{ + int i; + if ( line->n_allele==1 ) + { + kputc('.', str); + return; + } + if ( fmt->subscript>=0 ) + { + if ( line->n_allele > fmt->subscript+1 ) + kputs(line->d.allele[fmt->subscript+1], str); + else + kputc('.', str); + return; + } + for (i=1; in_allele; i++) + { + if ( i>1 ) kputc(',', str); + kputs(line->d.allele[i], str); + } +} +static void process_first_alt(convert_t *convert, bcf1_t *line, fmt_t *fmt, int isample, kstring_t *str) +{ + if ( line->n_allele==1 ) + kputc('.', str); + else + kputs(line->d.allele[1], str); +} +static void process_qual(convert_t *convert, bcf1_t *line, fmt_t *fmt, int isample, kstring_t *str) +{ + if ( bcf_float_is_missing(line->qual) ) kputc('.', str); + else kputd(line->qual, str); +} +static void process_filter(convert_t *convert, bcf1_t *line, fmt_t *fmt, int isample, kstring_t *str) +{ + int i; + if ( line->d.n_flt ) + { + for (i=0; id.n_flt; i++) + { + if (i) kputc(';', str); + kputs(convert->header->id[BCF_DT_ID][line->d.flt[i]].key, str); + } + } + else kputc('.', str); +} +static inline int32_t bcf_array_ivalue(void *bcf_array, int type, int idx) +{ + if ( type==BCF_BT_INT8 ) + { + int8_t val = ((int8_t*)bcf_array)[idx]; + if ( val==bcf_int8_missing ) return bcf_int32_missing; + if ( val==bcf_int8_vector_end ) return bcf_int32_vector_end; + return val; + } + if ( type==BCF_BT_INT16 ) + { + int16_t val = ((int16_t*)bcf_array)[idx]; + if ( val==bcf_int16_missing ) return bcf_int32_missing; + if ( val==bcf_int16_vector_end ) return bcf_int32_vector_end; + return val; + } + return ((int32_t*)bcf_array)[idx]; +} +static void process_info(convert_t *convert, bcf1_t *line, fmt_t *fmt, int isample, kstring_t *str) +{ + if ( fmt->id<0 ) + { + kputc('.', str); + return; + } + + int i; + for (i=0; in_info; i++) + if ( line->d.info[i].key == fmt->id ) break; + + // output "." if the tag is not present + if ( i==line->n_info ) + { + kputc('.', str); + return; + } + + bcf_info_t *info = &line->d.info[i]; + + // if this is a flag, output 1 + if ( info->len <=0 ) + { + kputc('1', str); + return; + } + + if ( info->len == 1 ) + { + switch (info->type) + { + case BCF_BT_INT8: if ( info->v1.i==bcf_int8_missing ) kputc('.', str); else kputw(info->v1.i, str); break; + case BCF_BT_INT16: if ( info->v1.i==bcf_int16_missing ) kputc('.', str); else kputw(info->v1.i, str); break; + case BCF_BT_INT32: if ( info->v1.i==bcf_int32_missing ) kputc('.', str); else kputw(info->v1.i, str); break; + case BCF_BT_FLOAT: if ( bcf_float_is_missing(info->v1.f) ) kputc('.', str); else kputd(info->v1.f, str); break; + case BCF_BT_CHAR: kputc(info->v1.i, str); break; + default: fprintf(stderr,"todo: type %d\n", info->type); exit(1); break; + } + } + else if ( fmt->subscript >=0 ) + { + if ( info->len <= fmt->subscript ) + { + kputc('.', str); + return; + } + #define BRANCH(type_t, is_missing, is_vector_end, kprint) { \ + type_t val = ((type_t *) info->vptr)[fmt->subscript]; \ + if ( is_missing || is_vector_end ) kputc('.',str); \ + else kprint; \ + } + switch (info->type) + { + case BCF_BT_INT8: BRANCH(int8_t, val==bcf_int8_missing, val==bcf_int8_vector_end, kputw(val, str)); break; + case BCF_BT_INT16: BRANCH(int16_t, val==bcf_int16_missing, val==bcf_int16_vector_end, kputw(val, str)); break; + case BCF_BT_INT32: BRANCH(int32_t, val==bcf_int32_missing, val==bcf_int32_vector_end, kputw(val, str)); break; + case BCF_BT_FLOAT: BRANCH(float, bcf_float_is_missing(val), bcf_float_is_vector_end(val), kputd(val, str)); break; + default: fprintf(stderr,"todo: type %d\n", info->type); exit(1); break; + } + #undef BRANCH + } + else + bcf_fmt_array(str, info->len, info->type, info->vptr); +} +static void init_format(convert_t *convert, bcf1_t *line, fmt_t *fmt) +{ + fmt->id = bcf_hdr_id2int(convert->header, BCF_DT_ID, fmt->key); + if ( !bcf_hdr_idinfo_exists(convert->header,BCF_HL_FMT,fmt->id) ) fmt->id = -1; + fmt->fmt = NULL; + if ( fmt->id >= 0 ) + { + int i; + for (i=0; i<(int)line->n_fmt; i++) + if ( line->d.fmt[i].id==fmt->id ) { fmt->fmt = &line->d.fmt[i]; break; } + } + else if ( !convert->allow_undef_tags ) + error("Error: no such tag defined in the VCF header: FORMAT/%s\n", fmt->key); + + fmt->ready = 1; +} +static void process_format(convert_t *convert, bcf1_t *line, fmt_t *fmt, int isample, kstring_t *str) +{ + if ( !fmt->ready ) + init_format(convert, line, fmt); + + if ( fmt->fmt==NULL ) + { + kputc('.', str); + return; + } + else if ( fmt->subscript >=0 ) + { + if ( fmt->fmt->n <= fmt->subscript ) + { + kputc('.', str); + return; + } + if ( fmt->fmt->type == BCF_BT_FLOAT ) + { + float *ptr = (float*)(fmt->fmt->p + isample*fmt->fmt->size); + if ( bcf_float_is_missing(ptr[fmt->subscript]) || bcf_float_is_vector_end(ptr[fmt->subscript]) ) + kputc('.', str); + else + kputd(ptr[fmt->subscript], str); + } + else if ( fmt->fmt->type != BCF_BT_CHAR ) + { + int32_t ival = bcf_array_ivalue(fmt->fmt->p+isample*fmt->fmt->size,fmt->fmt->type,fmt->subscript); + if ( ival==bcf_int32_missing || ival==bcf_int32_vector_end ) + kputc('.', str); + else + kputw(ival, str); + } + else error("TODO: %s:%d .. fmt->type=%d\n", __FILE__,__LINE__, fmt->fmt->type); + } + else + bcf_fmt_array(str, fmt->fmt->n, fmt->fmt->type, fmt->fmt->p + isample*fmt->fmt->size); +} +static void process_gt(convert_t *convert, bcf1_t *line, fmt_t *fmt, int isample, kstring_t *str) +{ + if ( !fmt->ready ) + init_format(convert, line, fmt); + + if ( fmt->fmt==NULL ) + { + kputc('.', str); + return; + } + bcf_format_gt(fmt->fmt, isample, str); +} +static void process_tgt(convert_t *convert, bcf1_t *line, fmt_t *fmt, int isample, kstring_t *str) +{ + if ( !fmt->ready ) + init_format(convert, line, fmt); + + if ( fmt->fmt==NULL ) + { + kputc('.', str); + return; + } + + assert( fmt->fmt->type==BCF_BT_INT8 ); + + int l; + int8_t *x = (int8_t*)(fmt->fmt->p + isample*fmt->fmt->size); // FIXME: does not work with n_alt >= 64 + for (l = 0; l < fmt->fmt->n && x[l] != bcf_int8_vector_end; ++l) + { + if (l) kputc("/|"[x[l]&1], str); + if (x[l]>>1) + { + int ial = (x[l]>>1) - 1; + kputs(line->d.allele[ial], str); + } + else + kputc('.', str); + } + if (l == 0) kputc('.', str); +} +static void destroy_tbcsq(void *usr) +{ + if ( !usr ) return; + bcsq_t *csq = (bcsq_t*) usr; + free(csq->hap1.s); + free(csq->hap2.s); + if ( csq->n ) + free(csq->str[0]); + free(csq->str); + free(csq); +} +static void process_tbcsq(convert_t *convert, bcf1_t *line, fmt_t *fmt, int isample, kstring_t *str) +{ + if ( !fmt->ready ) + { + init_format(convert, line, fmt); + + bcsq_t *csq; + if ( fmt->usr ) + { + csq = (bcsq_t*) fmt->usr; + if ( csq->n ) + free(csq->str[0]); + csq->n = 0; + } + else + csq = (bcsq_t*) calloc(1,sizeof(bcsq_t)); + fmt->usr = csq; + + int i=0, len = 0; + char *tmp = NULL; + if ( bcf_get_info_string(convert->header,line,fmt->key,&tmp,&len)<0 ) + { + csq->n = 0; + return; + } + do + { + csq->n++; + hts_expand(char*, csq->n, csq->m, csq->str); + csq->str[ csq->n-1 ] = tmp + i; + while ( iusr; + + if ( fmt->fmt==NULL || !csq->n ) return; + + csq->hap1.l = 0; + csq->hap2.l = 0; + + int mask = fmt->subscript==0 ? 3 : 1; // merge both haplotypes if subscript==0 + + #define BRANCH(type_t, nbits) { \ + type_t *x = (type_t*)(fmt->fmt->p + isample*fmt->fmt->size); \ + int i,j; \ + if ( fmt->subscript<=0 || fmt->subscript==1 ) \ + { \ + for (j=0; j < fmt->fmt->n; j++) \ + { \ + type_t val = x[j]; \ + if ( !val ) continue; \ + for (i=0; istr[(j*32+i)/2], &csq->hap1); kputc_(',', &csq->hap1); } \ + } \ + } \ + if ( fmt->subscript<0 || fmt->subscript==2 ) \ + { \ + for (j=0; j < fmt->fmt->n; j++) \ + { \ + type_t val = x[j]; \ + if ( !val ) continue; \ + for (i=1; istr[(j*32+i)/2], &csq->hap2); kputc_(',', &csq->hap2); } \ + } \ + } \ + } + switch (fmt->fmt->type) + { + case BCF_BT_INT8: BRANCH(uint8_t, 8); break; + case BCF_BT_INT16: BRANCH(uint16_t,16); break; + case BCF_BT_INT32: BRANCH(uint32_t,32); break; + default: error("Unexpected type: %d\n", fmt->fmt->type); exit(1); break; + } + #undef BRANCH + + if ( !csq->hap1.l && !csq->hap2.l ) return; + + if ( csq->hap1.l ) csq->hap1.s[--csq->hap1.l] = 0; + if ( csq->hap2.l ) csq->hap2.s[--csq->hap2.l] = 0; + + if ( fmt->subscript<0 ) + { + kputs(csq->hap1.l?csq->hap1.s:".", str); + kputc_('\t', str); + kputs(csq->hap2.l?csq->hap2.s:".", str); + } + else if ( fmt->subscript<2 ) + kputs(csq->hap1.l?csq->hap1.s:".", str); + else + kputs(csq->hap2.l?csq->hap2.s:".", str); +} +static void init_format_iupac(convert_t *convert, bcf1_t *line, fmt_t *fmt) +{ + init_format(convert, line, fmt); + if ( fmt->fmt==NULL ) return; + + // Init mapping between alleles and IUPAC table + hts_expand(uint8_t, line->n_allele, convert->ndat, convert->dat); + int8_t *dat = (int8_t*)convert->dat; + int i; + for (i=0; in_allele; i++) + { + if ( line->d.allele[i][1] ) dat[i] = -1; + else + { + switch (line->d.allele[i][0]) + { + case 'A': dat[i] = 0; break; + case 'C': dat[i] = 1; break; + case 'G': dat[i] = 2; break; + case 'T': dat[i] = 3; break; + case 'a': dat[i] = 0; break; + case 'c': dat[i] = 1; break; + case 'g': dat[i] = 2; break; + case 't': dat[i] = 3; break; + default: dat[i] = -1; + } + } + } +} +static void process_iupac_gt(convert_t *convert, bcf1_t *line, fmt_t *fmt, int isample, kstring_t *str) +{ + if ( !fmt->ready ) + init_format_iupac(convert, line, fmt); + + if ( fmt->fmt==NULL ) + { + kputc('.', str); + return; + } + + assert( fmt->fmt->type==BCF_BT_INT8 ); + + static const char iupac[4][4] = { {'A','M','R','W'},{'M','C','S','Y'},{'R','S','G','K'},{'W','Y','K','T'} }; + int8_t *dat = (int8_t*)convert->dat; + + int8_t *x = (int8_t*)(fmt->fmt->p + isample*fmt->fmt->size); // FIXME: does not work with n_alt >= 64 + int l = 0; + while ( lfmt->n && x[l]!=bcf_int8_vector_end && x[l]!=bcf_int8_missing ) l++; + + if ( l==2 ) + { + // diploid + int ia = (x[0]>>1) - 1, ib = (x[1]>>1) - 1; + if ( ia>=0 && ian_allele && ib>=0 && ibn_allele && dat[ia]>=0 && dat[ib]>=0 ) + { + kputc(iupac[dat[ia]][dat[ib]], str); + return; + } + } + for (l = 0; l < fmt->fmt->n && x[l] != bcf_int8_vector_end; ++l) + { + if (l) kputc("/|"[x[l]&1], str); + if (x[l]>>1) + { + int ial = (x[l]>>1) - 1; + kputs(line->d.allele[ial], str); + } + else + kputc('.', str); + } + if (l == 0) kputc('.', str); +} +static void process_sample(convert_t *convert, bcf1_t *line, fmt_t *fmt, int isample, kstring_t *str) +{ + kputs(convert->header->samples[isample], str); +} +static void process_sep(convert_t *convert, bcf1_t *line, fmt_t *fmt, int isample, kstring_t *str) { if (fmt->key) kputs(fmt->key, str); } +static void process_is_ts(convert_t *convert, bcf1_t *line, fmt_t *fmt, int isample, kstring_t *str) +{ + int is_ts = 0; + if ( bcf_get_variant_types(line) & (VCF_SNP|VCF_MNP) ) + is_ts = abs(bcf_acgt2int(*line->d.allele[0])-bcf_acgt2int(*line->d.allele[1])) == 2 ? 1 : 0; + kputc(is_ts ? '1' : '0', str); +} +static void process_type(convert_t *convert, bcf1_t *line, fmt_t *fmt, int isample, kstring_t *str) +{ + int line_type = bcf_get_variant_types(line); + int i = 0; + if ( line_type == VCF_REF ) { kputs("REF", str); i++; } + if ( line_type & VCF_SNP ) { if (i) kputc(',',str); kputs("SNP", str); i++; } + if ( line_type & VCF_MNP ) { if (i) kputc(',',str); kputs("MNP", str); i++; } + if ( line_type & VCF_INDEL ) { if (i) kputc(',',str); kputs("INDEL", str); i++; } + if ( line_type & VCF_OTHER ) { if (i) kputc(',',str); kputs("OTHER", str); i++; } + if ( line_type & VCF_BND ) { if (i) kputc(',',str); kputs("BND", str); i++; } +} +static void process_line(convert_t *convert, bcf1_t *line, fmt_t *fmt, int isample, kstring_t *str) +{ + vcf_format1(convert->header, line, str); +} +static void process_chrom_pos_id(convert_t *convert, bcf1_t *line, fmt_t *fmt, int isample, kstring_t *str) +{ + if ( line->d.id[0]!='.' || line->d.id[1] ) + { + // ID is present + kputs(line->d.id, str); + } + else + { + // use CHROM:POS instead of ID + kputs(convert->header->id[BCF_DT_CTG][line->rid].key, str); + kputc(':', str); + kputw(line->pos+1, str); + } +} +static void process_gt_to_prob3(convert_t *convert, bcf1_t *line, fmt_t *fmt, int isample, kstring_t *str) +{ + int m,n,i; + + m = convert->ndat / sizeof(int32_t); + n = bcf_get_genotypes(convert->header,line,&convert->dat,&m); + convert->ndat = m * sizeof(int32_t); + + if ( n<=0 ) + { + // Throw an error or silently proceed? + // + // for (i=0; insamples; i++) kputs(" 0.33 0.33 0.33", str); + // return; + + error("Error parsing GT tag at %s:%d\n", bcf_seqname(convert->header,line),line->pos+1); + } + + n /= convert->nsamples; + for (i=0; insamples; i++) + { + int32_t *ptr = (int32_t*)convert->dat + i*n; + int j; + for (j=0; jndat / sizeof(int32_t); + n = bcf_get_format_int32(convert->header,line,"PL",&convert->dat,&m); + convert->ndat = m * sizeof(int32_t); + + if ( n<=0 ) + { + // Throw an error or silently proceed? + // + // for (i=0; insamples; i++) kputs(" 0.33 0.33 0.33", str); + // return; + + error("Error parsing PL tag at %s:%d\n", bcf_seqname(convert->header,line),line->pos+1); + } + + n /= convert->nsamples; + for (i=0; insamples; i++) + { + int32_t *ptr = (int32_t*)convert->dat + i*n; + int j; + float sum = 0; + for (j=0; jn_allele ) + { + // haploid + kputc(' ',str); + ksprintf(str,"%f",pow(10,-0.1*ptr[0])/sum); + kputs(" 0 ", str); + ksprintf(str,"%f",pow(10,-0.1*ptr[1])/sum); + } + else + { + // diploid + kputc(' ',str); + ksprintf(str,"%f",pow(10,-0.1*ptr[0])/sum); + kputc(' ',str); + ksprintf(str,"%f",pow(10,-0.1*ptr[1])/sum); + kputc(' ',str); + ksprintf(str,"%f",pow(10,-0.1*ptr[2])/sum); + } + } +} +static void process_gp_to_prob3(convert_t *convert, bcf1_t *line, fmt_t *fmt, int isample, kstring_t *str) +{ + int m,n,i; + + m = convert->ndat / sizeof(float); + n = bcf_get_format_float(convert->header,line,"GP",&convert->dat,&m); + convert->ndat = m * sizeof(float); + + if ( n<=0 ) + { + // Throw an error or silently proceed? + // + // for (i=0; insamples; i++) kputs(" 0.33 0.33 0.33", str); + // return; + + error("Error parsing GP tag at %s:%d\n", bcf_seqname(convert->header,line),line->pos+1); + } + + n /= convert->nsamples; + for (i=0; insamples; i++) + { + float sum = 0, *ptr = (float*)convert->dat + i*n; + int j; + for (j=0; j1 ) error("[%s:%d:%f] GP value outside range [0,1]; bcftools convert expects the VCF4.3+ spec for the GP field encoding genotype posterior probabilities", bcf_seqname(convert->header,line),line->pos+1,ptr[j]); + sum+=ptr[j]; + } + if ( j==line->n_allele ) + ksprintf(str," %f %f %f",ptr[0],0.,ptr[1]); // haploid + else + ksprintf(str," %f %f %f",ptr[0],ptr[1],ptr[2]); // diploid + } +} + +static void process_gt_to_hap(convert_t *convert, bcf1_t *line, fmt_t *fmt, int isample, kstring_t *str) +{ + // https://mathgen.stats.ox.ac.uk/impute/impute_v2.html#-known_haps_g + + // File containing known haplotypes for the study cohort. The format + // is the same as the output format from IMPUTE2's -phase option: + // five header columns (as in the -g file) followed by two columns + // (haplotypes) per individual. Allowed values in the haplotype + // columns are 0, 1, and ?. + + // If your study dataset is fully phased, you can replace the -g file + // with a -known_haps_g file. This will cause IMPUTE2 to perform + // haploid imputation, although it will still report diploid imputation + // probabilities in the main output file. If any genotypes are missing, + // they can be marked as '? ?' (two question marks separated by one + // space) in the input file. (The program does not allow just one + // allele from a diploid genotype to be missing.) If the reference + // panels are also phased, IMPUTE2 will perform a single, fast + // imputation step rather than its standard MCMC module this is how + // the program imputes into pre-phased GWAS haplotypes. + + // The -known_haps_g file can also be used to specify study + // genotypes that are "partially" phased, in the sense that some + // genotypes are phased relative to a fixed reference point while + // others are not. We anticipate that this will be most useful when + // trying to phase resequencing data onto a scaffold of known + // haplotypes. To mark a known genotype as unphased, place an + // asterisk immediately after each allele, with no space between + // the allele (0/1) and the asterisk (*); e.g., "0* 1*" for a + // heterozygous genotype of unknown phase. + + int i, gt_id = bcf_hdr_id2int(convert->header, BCF_DT_ID, "GT"); + if ( !bcf_hdr_idinfo_exists(convert->header,BCF_HL_FMT,gt_id) ) + error("FORMAT/GT tag not present at %s:%d\n", bcf_seqname(convert->header, line), line->pos+1); + if ( !(line->unpacked & BCF_UN_FMT) ) bcf_unpack(line, BCF_UN_FMT); + bcf_fmt_t *fmt_gt = NULL; + for (i=0; in_fmt; i++) + if ( line->d.fmt[i].id==gt_id ) { fmt_gt = &line->d.fmt[i]; break; } + if ( !fmt_gt ) + error("FORMAT/GT tag not present at %s:%d\n", bcf_seqname(convert->header, line), line->pos+1); + + // Alloc all memory in advance to avoid kput routines. The biggest allowed allele index is 99 + if ( line->n_allele > 100 ) + error("Too many alleles (%d) at %s:%d\n", line->n_allele, bcf_seqname(convert->header, line), line->pos+1); + if ( ks_resize(str, str->l+convert->nsamples*8) != 0 ) + error("Could not alloc %d bytes\n", str->l + convert->nsamples*8); + + if ( fmt_gt->type!=BCF_BT_INT8 ) // todo: use BRANCH_INT if the VCF is valid + error("Uh, too many alleles (%d) or redundant BCF representation at %s:%d\n", line->n_allele, bcf_seqname(convert->header, line), line->pos+1); + + int8_t *ptr = ((int8_t*) fmt_gt->p) - fmt_gt->n; + for (i=0; insamples; i++) + { + ptr += fmt_gt->n; + if ( ptr[0]==2 ) + { + if ( ptr[1]==3 ) /* 0|0 */ + { + str->s[str->l++] = '0'; str->s[str->l++] = ' '; str->s[str->l++] = '0'; str->s[str->l++] = ' '; + } + else if ( ptr[1]==5 ) /* 0|1 */ + { + str->s[str->l++] = '0'; str->s[str->l++] = ' '; str->s[str->l++] = '1'; str->s[str->l++] = ' '; + } + else if ( ptr[1]==bcf_int8_vector_end ) /* 0 */ + { + str->s[str->l++] = '0'; str->s[str->l++] = ' '; str->s[str->l++] = '-'; str->s[str->l++] = ' '; + } + else if ( ptr[1]==2 ) /* 0/0 */ + { + str->s[str->l++] = '0'; str->s[str->l++] = '*'; str->s[str->l++] = ' '; str->s[str->l++] = '0'; str->s[str->l++] = '*'; str->s[str->l++] = ' '; + } + else if ( ptr[1]==4 ) /* 0/1 */ + { + str->s[str->l++] = '0'; str->s[str->l++] = '*'; str->s[str->l++] = ' '; str->s[str->l++] = '1'; str->s[str->l++] = '*'; str->s[str->l++] = ' '; + } + else if ( bcf_gt_is_missing(ptr[1]) ) /* 0/. */ + { + str->s[str->l++] = '?'; str->s[str->l++] = ' '; str->s[str->l++] = '?'; str->s[str->l++] = ' '; + } + else if ( bcf_gt_is_phased(ptr[1]) ) /* 0|x */ + { + str->s[str->l++] = '0'; str->s[str->l++] = ' '; + kputw(bcf_gt_allele(ptr[1]),str); + str->s[str->l++] = ' '; + } + else /* 0/x */ + { + str->s[str->l++] = '0'; str->s[str->l++] = '*'; str->s[str->l++] = ' '; + kputw(bcf_gt_allele(ptr[1]),str); + str->s[str->l++] = '*'; str->s[str->l++] = ' '; + } + } + else if ( ptr[0]==4 ) + { + if ( ptr[1]==3 ) /* 1|0 */ + { + str->s[str->l++] = '1'; str->s[str->l++] = ' '; str->s[str->l++] = '0'; str->s[str->l++] = ' '; + } + else if ( ptr[1]==5 ) /* 1|1 */ + { + str->s[str->l++] = '1'; str->s[str->l++] = ' '; str->s[str->l++] = '1'; str->s[str->l++] = ' '; + } + else if ( ptr[1]==bcf_int8_vector_end ) /* 1 */ + { + str->s[str->l++] = '1'; str->s[str->l++] = ' '; str->s[str->l++] = '-'; str->s[str->l++] = ' '; + } + else if ( ptr[1]==2 ) /* 1/0 */ + { + str->s[str->l++] = '1'; str->s[str->l++] = '*'; str->s[str->l++] = ' '; str->s[str->l++] = '0'; str->s[str->l++] = '*'; str->s[str->l++] = ' '; + } + else if ( ptr[1]==4 ) /* 1/1 */ + { + str->s[str->l++] = '1'; str->s[str->l++] = '*'; str->s[str->l++] = ' '; str->s[str->l++] = '1'; str->s[str->l++] = '*'; str->s[str->l++] = ' '; + } + else if ( bcf_gt_is_missing(ptr[1]) ) /* 1/. */ + { + str->s[str->l++] = '?'; str->s[str->l++] = ' '; str->s[str->l++] = '?'; str->s[str->l++] = ' '; + } + else if ( bcf_gt_is_phased(ptr[1]) ) /* 1|x */ + { + str->s[str->l++] = '1'; str->s[str->l++] = ' '; + kputw(bcf_gt_allele(ptr[1]),str); + str->s[str->l++] = ' '; + } + else /* 1/x */ + { + str->s[str->l++] = '1'; str->s[str->l++] = '*'; str->s[str->l++] = ' '; + kputw(bcf_gt_allele(ptr[1]),str); + str->s[str->l++] = '*'; str->s[str->l++] = ' '; + } + } + else if ( bcf_gt_is_missing(ptr[0]) ) + { + if ( ptr[1]==bcf_int8_vector_end ) + { + str->s[str->l++] = '?'; str->s[str->l++] = ' '; str->s[str->l++] = '-'; str->s[str->l++] = ' '; + } + else + { + str->s[str->l++] = '?'; str->s[str->l++] = ' '; str->s[str->l++] = '?'; str->s[str->l++] = ' '; + } + } + else if ( ptr[1]==bcf_int8_vector_end ) + { + /* use REF for something else than first ALT */ + str->s[str->l++] = '0'; str->s[str->l++] = ' '; str->s[str->l++] = '-'; str->s[str->l++] = ' '; + } + else + { + kputw(bcf_gt_allele(ptr[0]),str); + if ( bcf_gt_is_phased(ptr[1]) ) str->s[str->l++] = '*'; + str->s[str->l++] = ' '; + kputw(bcf_gt_allele(ptr[1]),str); + if ( bcf_gt_is_phased(ptr[1]) ) str->s[str->l++] = '*'; + str->s[str->l++] = ' '; + } + } + str->s[--str->l] = 0; // delete the last space +} +static void process_gt_to_hap2(convert_t *convert, bcf1_t *line, fmt_t *fmt, int isample, kstring_t *str) +{ + // same as process_gt_to_hap but converts haploid genotypes into diploid + + int i, gt_id = bcf_hdr_id2int(convert->header, BCF_DT_ID, "GT"); + if ( !bcf_hdr_idinfo_exists(convert->header,BCF_HL_FMT,gt_id) ) + error("FORMAT/GT tag not present at %s:%d\n", bcf_seqname(convert->header, line), line->pos+1); + if ( !(line->unpacked & BCF_UN_FMT) ) bcf_unpack(line, BCF_UN_FMT); + bcf_fmt_t *fmt_gt = NULL; + for (i=0; in_fmt; i++) + if ( line->d.fmt[i].id==gt_id ) { fmt_gt = &line->d.fmt[i]; break; } + if ( !fmt_gt ) + error("FORMAT/GT tag not present at %s:%d\n", bcf_seqname(convert->header, line), line->pos+1); + + // Alloc all memory in advance to avoid kput routines. The biggest allowed allele index is 99 + if ( line->n_allele > 100 ) + error("Too many alleles (%d) at %s:%d\n", line->n_allele, bcf_seqname(convert->header, line), line->pos+1); + if ( ks_resize(str, str->l+convert->nsamples*8) != 0 ) + error("Could not alloc %d bytes\n", str->l + convert->nsamples*8); + + if ( fmt_gt->type!=BCF_BT_INT8 ) // todo: use BRANCH_INT if the VCF is valid + error("Uh, too many alleles (%d) or redundant BCF representation at %s:%d\n", line->n_allele, bcf_seqname(convert->header, line), line->pos+1); + + int8_t *ptr = ((int8_t*) fmt_gt->p) - fmt_gt->n; + for (i=0; insamples; i++) + { + ptr += fmt_gt->n; + if ( ptr[0]==2 ) + { + if ( ptr[1]==3 ) /* 0|0 */ + { + str->s[str->l++] = '0'; str->s[str->l++] = ' '; str->s[str->l++] = '0'; str->s[str->l++] = ' '; + } + else if ( ptr[1]==5 ) /* 0|1 */ + { + str->s[str->l++] = '0'; str->s[str->l++] = ' '; str->s[str->l++] = '1'; str->s[str->l++] = ' '; + } + else if ( ptr[1]==bcf_int8_vector_end ) /* 0 -> 0|0 */ + { + str->s[str->l++] = '0'; str->s[str->l++] = ' '; str->s[str->l++] = '0'; str->s[str->l++] = ' '; + } + else if ( ptr[1]==2 ) /* 0/0 */ + { + str->s[str->l++] = '0'; str->s[str->l++] = '*'; str->s[str->l++] = ' '; str->s[str->l++] = '0'; str->s[str->l++] = '*'; str->s[str->l++] = ' '; + } + else if ( ptr[1]==4 ) /* 0/1 */ + { + str->s[str->l++] = '0'; str->s[str->l++] = '*'; str->s[str->l++] = ' '; str->s[str->l++] = '1'; str->s[str->l++] = '*'; str->s[str->l++] = ' '; + } + else if ( bcf_gt_is_missing(ptr[1]) ) /* 0/. */ + { + str->s[str->l++] = '?'; str->s[str->l++] = ' '; str->s[str->l++] = '?'; str->s[str->l++] = ' '; + } + else if ( bcf_gt_is_phased(ptr[1]) ) /* 0|x */ + { + str->s[str->l++] = '0'; str->s[str->l++] = ' '; + kputw(bcf_gt_allele(ptr[1]),str); + str->s[str->l++] = ' '; + } + else /* 0/x */ + { + str->s[str->l++] = '0'; str->s[str->l++] = '*'; str->s[str->l++] = ' '; + kputw(bcf_gt_allele(ptr[1]),str); + str->s[str->l++] = '*'; str->s[str->l++] = ' '; + } + } + else if ( ptr[0]==4 ) + { + if ( ptr[1]==3 ) /* 1|0 */ + { + str->s[str->l++] = '1'; str->s[str->l++] = ' '; str->s[str->l++] = '0'; str->s[str->l++] = ' '; + } + else if ( ptr[1]==5 ) /* 1|1 */ + { + str->s[str->l++] = '1'; str->s[str->l++] = ' '; str->s[str->l++] = '1'; str->s[str->l++] = ' '; + } + else if ( ptr[1]==bcf_int8_vector_end ) /* 1 -> 1|1 */ + { + str->s[str->l++] = '1'; str->s[str->l++] = ' '; str->s[str->l++] = '1'; str->s[str->l++] = ' '; + } + else if ( ptr[1]==2 ) /* 1/0 */ + { + str->s[str->l++] = '1'; str->s[str->l++] = '*'; str->s[str->l++] = ' '; str->s[str->l++] = '0'; str->s[str->l++] = '*'; str->s[str->l++] = ' '; + } + else if ( ptr[1]==4 ) /* 1/1 */ + { + str->s[str->l++] = '1'; str->s[str->l++] = '*'; str->s[str->l++] = ' '; str->s[str->l++] = '1'; str->s[str->l++] = '*'; str->s[str->l++] = ' '; + } + else if ( bcf_gt_is_missing(ptr[1]) ) /* 1/. */ + { + str->s[str->l++] = '?'; str->s[str->l++] = ' '; str->s[str->l++] = '?'; str->s[str->l++] = ' '; + } + else if ( bcf_gt_is_phased(ptr[1]) ) /* 1|x */ + { + str->s[str->l++] = '1'; str->s[str->l++] = ' '; + kputw(bcf_gt_allele(ptr[1]),str); + str->s[str->l++] = ' '; + } + else /* 1/x */ + { + str->s[str->l++] = '1'; str->s[str->l++] = '*'; str->s[str->l++] = ' '; + kputw(bcf_gt_allele(ptr[1]),str); + str->s[str->l++] = '*'; str->s[str->l++] = ' '; + } + } + else if ( bcf_gt_is_missing(ptr[0]) ) + { + str->s[str->l++] = '?'; str->s[str->l++] = ' '; str->s[str->l++] = '?'; str->s[str->l++] = ' '; + } + else if ( ptr[1]==bcf_int8_vector_end ) + { + /* use REF for something else than first ALT */ + str->s[str->l++] = '0'; str->s[str->l++] = ' '; str->s[str->l++] = '0'; str->s[str->l++] = ' '; + } + else + { + kputw(bcf_gt_allele(ptr[0]),str); + if ( bcf_gt_is_phased(ptr[1]) ) str->s[str->l++] = '*'; + str->s[str->l++] = ' '; + kputw(bcf_gt_allele(ptr[1]),str); + if ( bcf_gt_is_phased(ptr[1]) ) str->s[str->l++] = '*'; + str->s[str->l++] = ' '; + } + } + str->s[--str->l] = 0; // delete the last space +} + +static fmt_t *register_tag(convert_t *convert, int type, char *key, int is_gtf) +{ + convert->nfmt++; + if ( convert->nfmt > convert->mfmt ) + { + convert->mfmt += 10; + convert->fmt = (fmt_t*) realloc(convert->fmt, convert->mfmt*sizeof(fmt_t)); + } + fmt_t *fmt = &convert->fmt[ convert->nfmt-1 ]; + fmt->type = type; + fmt->key = key ? strdup(key) : NULL; + fmt->is_gt_field = is_gtf; + fmt->subscript = -1; + fmt->usr = NULL; + fmt->destroy = NULL; + + // Allow non-format tags, such as CHROM, INFO, etc., to appear amongst the format tags. + if ( key ) + { + int id = bcf_hdr_id2int(convert->header, BCF_DT_ID, key); + if ( fmt->type==T_FORMAT && !bcf_hdr_idinfo_exists(convert->header,BCF_HL_FMT,id) ) + { + if ( !strcmp("CHROM",key) ) { fmt->type = T_CHROM; } + else if ( !strcmp("POS",key) ) { fmt->type = T_POS; } + else if ( !strcmp("POS0",key) ) { fmt->type = T_POS0; } + else if ( !strcmp("END",key) ) { fmt->type = T_END; } + else if ( !strcmp("END0",key) ) { fmt->type = T_END0; } + else if ( !strcmp("ID",key) ) { fmt->type = T_ID; } + else if ( !strcmp("REF",key) ) { fmt->type = T_REF; } + else if ( !strcmp("ALT",key) ) { fmt->type = T_ALT; } + else if ( !strcmp("FIRST_ALT",key) ) { fmt->type = T_FIRST_ALT; } + else if ( !strcmp("QUAL",key) ) { fmt->type = T_QUAL; } + else if ( !strcmp("FILTER",key) ) { fmt->type = T_FILTER; } + else if ( !strcmp("_CHROM_POS_ID",key) ) { fmt->type = T_CHROM_POS_ID; } + else if ( id>=0 && bcf_hdr_idinfo_exists(convert->header,BCF_HL_INFO,id) ) + { + fmt->type = T_INFO; + fprintf(stderr,"Warning: Assuming INFO/%s\n", key); + } + } + } + + switch (fmt->type) + { + case T_FIRST_ALT: fmt->handler = &process_first_alt; break; + case T_CHROM_POS_ID: fmt->handler = &process_chrom_pos_id; break; + case T_GT_TO_PROB3: fmt->handler = &process_gt_to_prob3; break; + case T_PL_TO_PROB3: fmt->handler = &process_pl_to_prob3; break; + case T_GP_TO_PROB3: fmt->handler = &process_gp_to_prob3; break; + case T_CHROM: fmt->handler = &process_chrom; break; + case T_POS: fmt->handler = &process_pos; break; + case T_POS0: fmt->handler = &process_pos0; break; + case T_END: fmt->handler = &process_end; break; + case T_END0: fmt->handler = &process_end0; break; + case T_ID: fmt->handler = &process_id; break; + case T_REF: fmt->handler = &process_ref; break; + case T_ALT: fmt->handler = &process_alt; break; + case T_QUAL: fmt->handler = &process_qual; break; + case T_FILTER: fmt->handler = &process_filter; convert->max_unpack |= BCF_UN_FLT; break; + case T_INFO: fmt->handler = &process_info; convert->max_unpack |= BCF_UN_INFO; break; + case T_FORMAT: fmt->handler = &process_format; convert->max_unpack |= BCF_UN_FMT; break; + case T_SAMPLE: fmt->handler = &process_sample; break; + case T_SEP: fmt->handler = &process_sep; break; + case T_IS_TS: fmt->handler = &process_is_ts; break; + case T_TYPE: fmt->handler = &process_type; break; + case T_MASK: fmt->handler = NULL; break; + case T_GT: fmt->handler = &process_gt; convert->max_unpack |= BCF_UN_FMT; break; + case T_TGT: fmt->handler = &process_tgt; convert->max_unpack |= BCF_UN_FMT; break; + case T_IUPAC_GT: fmt->handler = &process_iupac_gt; convert->max_unpack |= BCF_UN_FMT; break; + case T_GT_TO_HAP: fmt->handler = &process_gt_to_hap; convert->max_unpack |= BCF_UN_FMT; break; + case T_GT_TO_HAP2: fmt->handler = &process_gt_to_hap2; convert->max_unpack |= BCF_UN_FMT; break; + case T_TBCSQ: fmt->handler = &process_tbcsq; fmt->destroy = &destroy_tbcsq; convert->max_unpack |= BCF_UN_FMT; break; + case T_LINE: fmt->handler = &process_line; convert->max_unpack |= BCF_UN_FMT; break; + default: error("TODO: handler for type %d\n", fmt->type); + } + if ( key && fmt->type==T_INFO ) + { + fmt->id = bcf_hdr_id2int(convert->header, BCF_DT_ID, key); + if ( !bcf_hdr_idinfo_exists(convert->header,BCF_HL_INFO,fmt->id) ) + { + fmt->id = -1; + convert->undef_info_tag = strdup(key); + } + } + return fmt; +} + +static int parse_subscript(char **p) +{ + char *q = *p; + if ( *q!='{' ) return -1; + q++; + while ( *q && *q!='}' && isdigit(*q) ) q++; + if ( *q!='}' ) return -1; + int idx = atoi((*p)+1); + *p = q+1; + return idx; +} + +static char *parse_tag(convert_t *convert, char *p, int is_gtf) +{ + char *q = ++p; + while ( *q && (isalnum(*q) || *q=='_' || *q=='.') ) q++; + kstring_t str = {0,0,0}; + if ( q-p==0 ) error("Could not parse format string: %s\n", convert->format_str); + kputsn(p, q-p, &str); + if ( is_gtf ) + { + if ( !strcmp(str.s, "SAMPLE") ) register_tag(convert, T_SAMPLE, "SAMPLE", is_gtf); + else if ( !strcmp(str.s, "GT") ) register_tag(convert, T_GT, "GT", is_gtf); + else if ( !strcmp(str.s, "TGT") ) register_tag(convert, T_TGT, "GT", is_gtf); + else if ( !strcmp(str.s, "TBCSQ") ) + { + fmt_t *fmt = register_tag(convert, T_TBCSQ, "BCSQ", is_gtf); + fmt->subscript = parse_subscript(&q); + if ( fmt->subscript==-1 ) + { + if ( !strncmp(q,"{*}",3) ) { fmt->subscript = 0; q += 3; } + } + else fmt->subscript++; + } + else if ( !strcmp(str.s, "IUPACGT") ) register_tag(convert, T_IUPAC_GT, "GT", is_gtf); + else if ( !strcmp(str.s, "INFO") ) + { + if ( *q!='/' ) error("Could not parse format string: %s\n", convert->format_str); + p = ++q; + str.l = 0; + while ( *q && (isalnum(*q) || *q=='_' || *q=='.') ) q++; + if ( q-p==0 ) error("Could not parse format string: %s\n", convert->format_str); + kputsn(p, q-p, &str); + fmt_t *fmt = register_tag(convert, T_INFO, str.s, is_gtf); + fmt->subscript = parse_subscript(&q); + } + else + { + fmt_t *fmt = register_tag(convert, T_FORMAT, str.s, is_gtf); + fmt->subscript = parse_subscript(&q); + } + } + else + { + if ( !strcmp(str.s, "CHROM") ) register_tag(convert, T_CHROM, str.s, is_gtf); + else if ( !strcmp(str.s, "POS") ) register_tag(convert, T_POS, str.s, is_gtf); + else if ( !strcmp(str.s, "POS0") ) register_tag(convert, T_POS0, str.s, is_gtf); + else if ( !strcmp(str.s, "END") ) register_tag(convert, T_END, str.s, is_gtf); + else if ( !strcmp(str.s, "END0") ) register_tag(convert, T_END0, str.s, is_gtf); + else if ( !strcmp(str.s, "ID") ) register_tag(convert, T_ID, str.s, is_gtf); + else if ( !strcmp(str.s, "REF") ) register_tag(convert, T_REF, str.s, is_gtf); + else if ( !strcmp(str.s, "ALT") ) + { + fmt_t *fmt = register_tag(convert, T_ALT, str.s, is_gtf); + fmt->subscript = parse_subscript(&q); + } + else if ( !strcmp(str.s, "FIRST_ALT") ) register_tag(convert, T_FIRST_ALT, str.s, is_gtf); + else if ( !strcmp(str.s, "QUAL") ) register_tag(convert, T_QUAL, str.s, is_gtf); + else if ( !strcmp(str.s, "FILTER") ) register_tag(convert, T_FILTER, str.s, is_gtf); + else if ( !strcmp(str.s, "QUAL") ) register_tag(convert, T_QUAL, str.s, is_gtf); + else if ( !strcmp(str.s, "IS_TS") ) register_tag(convert, T_IS_TS, str.s, is_gtf); + else if ( !strcmp(str.s, "TYPE") ) register_tag(convert, T_TYPE, str.s, is_gtf); + else if ( !strcmp(str.s, "MASK") ) register_tag(convert, T_MASK, str.s, is_gtf); + else if ( !strcmp(str.s, "LINE") ) register_tag(convert, T_LINE, str.s, is_gtf); + else if ( !strcmp(str.s, "_CHROM_POS_ID") ) register_tag(convert, T_CHROM_POS_ID, str.s, is_gtf); + else if ( !strcmp(str.s, "_GT_TO_PROB3") ) register_tag(convert, T_GT_TO_PROB3, str.s, is_gtf); + else if ( !strcmp(str.s, "_PL_TO_PROB3") ) register_tag(convert, T_PL_TO_PROB3, str.s, is_gtf); + else if ( !strcmp(str.s, "_GP_TO_PROB3") ) register_tag(convert, T_GP_TO_PROB3, str.s, is_gtf); + else if ( !strcmp(str.s, "_GT_TO_HAP") ) register_tag(convert, T_GT_TO_HAP, str.s, is_gtf); + else if ( !strcmp(str.s, "_GT_TO_HAP2") ) register_tag(convert, T_GT_TO_HAP2, str.s, is_gtf); + else if ( !strcmp(str.s, "INFO") ) + { + if ( *q!='/' ) error("Could not parse format string: %s\n", convert->format_str); + p = ++q; + str.l = 0; + while ( *q && (isalnum(*q) || *q=='_' || *q=='.') ) q++; + if ( q-p==0 ) error("Could not parse format string: %s\n", convert->format_str); + kputsn(p, q-p, &str); + fmt_t *fmt = register_tag(convert, T_INFO, str.s, is_gtf); + fmt->subscript = parse_subscript(&q); + } + else + { + fmt_t *fmt = register_tag(convert, T_INFO, str.s, is_gtf); + fmt->subscript = parse_subscript(&q); + } + } + free(str.s); + return q; +} + +static char *parse_sep(convert_t *convert, char *p, int is_gtf) +{ + char *q = p; + kstring_t str = {0,0,0}; + while ( *q && *q!='[' && *q!=']' && *q!='%' ) + { + if ( *q=='\\' ) + { + q++; + if ( *q=='n' ) kputc('\n', &str); + else if ( *q=='t' ) kputc('\t', &str); + else kputc(*q, &str); + } + else kputc(*q, &str); + q++; + } + if ( !str.l ) error("Could not parse format string: %s\n", convert->format_str); + register_tag(convert, T_SEP, str.s, is_gtf); + free(str.s); + return q; +} + +convert_t *convert_init(bcf_hdr_t *hdr, int *samples, int nsamples, const char *format_str) +{ + convert_t *convert = (convert_t*) calloc(1,sizeof(convert_t)); + convert->header = hdr; + convert->format_str = strdup(format_str); + convert->max_unpack = BCF_UN_STR; + + int i, is_gtf = 0; + char *p = convert->format_str; + while ( *p ) + { + //fprintf(stderr,"<%s>\n", p); + switch (*p) + { + case '[': is_gtf = 1; p++; break; + case ']': is_gtf = 0; register_tag(convert, T_SEP, NULL, 0); p++; break; + case '%': p = parse_tag(convert, p, is_gtf); break; + default: p = parse_sep(convert, p, is_gtf); break; + } + } + if ( is_gtf ) + error("Could not parse the format string, missing the square bracket \"]\": %s\n", convert->format_str); + + if ( nsamples ) + { + convert->nsamples = nsamples; + convert->samples = (int*) malloc(sizeof(int)*nsamples); + for (i=0; insamples; i++) convert->samples[i] = samples[i]; + } + else + { + convert->nsamples = bcf_hdr_nsamples(convert->header); + convert->samples = (int*) malloc(sizeof(int)*convert->nsamples); + for (i=0; insamples; i++) convert->samples[i] = i; + } + return convert; +} + +void convert_destroy(convert_t *convert) +{ + int i; + for (i=0; infmt; i++) + { + if ( convert->fmt[i].destroy ) convert->fmt[i].destroy(convert->fmt[i].usr); + free(convert->fmt[i].key); + } + free(convert->fmt); + free(convert->undef_info_tag); + free(convert->dat); + free(convert->samples); + free(convert->format_str); + free(convert); +} + + +int convert_header(convert_t *convert, kstring_t *str) +{ + int i, icol = 0, l_ori = str->l; + bcf_hdr_t *hdr = convert->header; + + // Supress the header output if LINE is present + for (i=0; infmt; i++) + if ( convert->fmt[i].type == T_LINE ) break; + if ( i!=convert->nfmt ) + return str->l - l_ori; + + kputs("# ", str); + for (i=0; infmt; i++) + { + // Genotype fields + if ( convert->fmt[i].is_gt_field ) + { + int j = i, js, k; + while ( convert->fmt[j].is_gt_field ) j++; + for (js=0; jsnsamples; js++) + { + int ks = convert->samples[js]; + for (k=i; kfmt[k].type == T_SEP ) + { + if ( convert->fmt[k].key ) kputs(convert->fmt[k].key, str); + } + else if ( convert->fmt[k].type == T_SAMPLE ) + ksprintf(str, "[%d]%s", ++icol, convert->fmt[k].key); + else + ksprintf(str, "[%d]%s:%s", ++icol, hdr->samples[ks], convert->fmt[k].key); + } + } + i = j-1; + continue; + } + // Fixed fields + if ( convert->fmt[i].type == T_SEP ) + { + if ( convert->fmt[i].key ) kputs(convert->fmt[i].key, str); + continue; + } + ksprintf(str, "[%d]%s", ++icol, convert->fmt[i].key); + } + return str->l - l_ori; +} + +int convert_line(convert_t *convert, bcf1_t *line, kstring_t *str) +{ + if ( !convert->allow_undef_tags && convert->undef_info_tag ) + error("Error: no such tag defined in the VCF header: INFO/%s. FORMAT fields must be in square brackets, e.g. \"[ %s]\"\n", convert->undef_info_tag,convert->undef_info_tag); + + int l_ori = str->l; + bcf_unpack(line, convert->max_unpack); + + int i, ir; + str->l = 0; + for (i=0; infmt; i++) + { + // Genotype fields. + if ( convert->fmt[i].is_gt_field ) + { + int j = i, js, k; + while ( jnfmt && convert->fmt[j].is_gt_field ) + { + convert->fmt[j].ready = 0; + j++; + } + for (js=0; jsnsamples; js++) + { + // Here comes a hack designed for TBCSQ. When running on large files, + // such as 1000GP, there are too many empty fields in the output and + // it's very very slow. Therefore in case the handler does not add + // anything to the string, we trim all genotype fields enclosed in square + // brackets here. This may be changed in future, time will show... + size_t l_start = str->l; + + int ks = convert->samples[js]; + for (k=i; kfmt[k].type == T_MASK ) + { + for (ir=0; irnreaders; ir++) + kputc(bcf_sr_has_line(convert->readers,ir)?'1':'0', str); + } + else if ( convert->fmt[k].handler ) + { + size_t l = str->l; + convert->fmt[k].handler(convert, line, &convert->fmt[k], ks, str); + if ( l==str->l ) { str->l = l_start; break; } // only TBCSQ does this + } + } + } + i = j-1; + continue; + } + // Fixed fields + if ( convert->fmt[i].type == T_MASK ) + { + for (ir=0; irnreaders; ir++) + kputc(bcf_sr_has_line(convert->readers,ir)?'1':'0', str); + } + else if ( convert->fmt[i].handler ) + convert->fmt[i].handler(convert, line, &convert->fmt[i], -1, str); + + } + return str->l - l_ori; +} + +int convert_set_option(convert_t *convert, enum convert_option opt, ...) +{ + int ret = 0; + va_list args; + + va_start(args, opt); + switch (opt) + { + case allow_undef_tags: + convert->allow_undef_tags = va_arg(args, int); + break; + default: + ret = -1; + } + va_end(args); + return ret; +} + +int convert_max_unpack(convert_t *convert) +{ + return convert->max_unpack; +} + diff --git a/convert.h b/convert.h new file mode 100644 index 0000000..3712338 --- /dev/null +++ b/convert.h @@ -0,0 +1,44 @@ +/* convert.h -- functions for converting between VCF/BCF and related formats. + + Copyright (C) 2014 Genome Research Ltd. + + Author: Petr Danecek + +Permission is hereby granted, free of charge, to any person obtaining a copy +of this software and associated documentation files (the "Software"), to deal +in the Software without restriction, including without limitation the rights +to use, copy, modify, merge, publish, distribute, sublicense, and/or sell +copies of the Software, and to permit persons to whom the Software is +furnished to do so, subject to the following conditions: + +The above copyright notice and this permission notice shall be included in +all copies or substantial portions of the Software. + +THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE +AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER +LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, +OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN +THE SOFTWARE. */ + +#ifndef __CONVERT_H__ +#define __CONVERT_H__ + +#include + +typedef struct _convert_t convert_t; +enum convert_option +{ + allow_undef_tags +}; + +convert_t *convert_init(bcf_hdr_t *hdr, int *samples, int nsamples, const char *str); +void convert_destroy(convert_t *convert); +int convert_set_option(convert_t *convert, enum convert_option opt, ...); +int convert_header(convert_t *convert, kstring_t *str); +int convert_line(convert_t *convert, bcf1_t *rec, kstring_t *str); +int convert_max_unpack(convert_t *convert); + +#endif + diff --git a/csq.c b/csq.c new file mode 100644 index 0000000..b1db103 --- /dev/null +++ b/csq.c @@ -0,0 +1,3824 @@ +/* The MIT License + + Copyright (c) 2016 Genome Research Ltd. + + Author: Petr Danecek + + Permission is hereby granted, free of charge, to any person obtaining a copy + of this software and associated documentation files (the "Software"), to deal + in the Software without restriction, including without limitation the rights + to use, copy, modify, merge, publish, distribute, sublicense, and/or sell + copies of the Software, and to permit persons to whom the Software is + furnished to do so, subject to the following conditions: + + The above copyright notice and this permission notice shall be included in + all copies or substantial portions of the Software. + + THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR + IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, + FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE + AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER + LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, + OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN + THE SOFTWARE. + + */ +/* + Things that would be nice to have + - for stop-lost events (also in frameshifts) report the number of truncated aa's + - memory could be greatly reduced by indexing gff (but it is quite compact already) + - deletions that go beyond transcript boundaries are not checked at sequence level + - alloc tscript->ref in hap_finalize, introduce fa_off_beg:16,fa_off_end:16 + - see test/csq/ENST00000573314/insertion-overlap.vcf #1476288882 + + Read about transcript types here + http://vega.sanger.ac.uk/info/about/gene_and_transcript_types.html + http://www.ensembl.org/info/genome/variation/predicted_data.html + http://www.gencodegenes.org/gencode_biotypes.html + + List of supported biotypes + antisense + IG_C_gene + IG_D_gene + IG_J_gene + IG_LV_gene + IG_V_gene + lincRNA + macro_lncRNA + miRNA + misc_RNA + Mt_rRNA + Mt_tRNA + polymorphic_pseudogene + processed_transcript + protein_coding + ribozyme + rRNA + sRNA + scRNA + scaRNA + sense_intronic + sense_overlapping + snRNA + snoRNA + TR_C_gene + TR_D_gene + TR_J_gene + TR_V_gene + + The gff parsing logic + We collect features such by combining gff lines A,B,C as follows: + A .. gene line with a supported biotype + A.ID=~/^gene:/ + + B .. transcript line referencing A + B.ID=~/^transcript:/ && B.Parent=~/^gene:A.ID/ + + C .. corresponding CDS, exon, and UTR lines: + C[3] in {"CDS","exon","three_prime_UTR","five_prime_UTR"} && C.Parent=~/^transcript:B.ID/ + + For coding biotypes ("protein_coding" or "polymorphic_pseudogene") the + complete chain link C -> B -> A is required. For the rest, link B -> A suffices. + + + The supported consequence types, sorted by impact: + splice_acceptor_variant .. end region of an intron changed (2bp at the 3' end of an intron) + splice_donor_variant .. start region of an intron changed (2bp at the 5' end of an intron) + stop_gained .. DNA sequence variant resulting in a stop codon + frameshift_variant .. number of inserted/deleted bases not a multiple of three, disrupted translational frame + stop_lost .. elongated transcript, stop codon changed + start_lost .. the first codon changed + inframe_altering .. combination of indels leading to unchanged reading frame and length + inframe_insertion .. inserted coding sequence, unchanged reading frame + inframe_deletion .. deleted coding sequence, unchanged reading frame + missense_variant .. amino acid (aa) change, unchanged length + splice_region_variant .. change within 1-3 bases of the exon or 3-8 bases of the intron + synonymous_variant .. DNA sequence variant resulting in no amino acid change + stop_retained_variant .. different stop codon + non_coding_variant .. variant in non-coding sequence, such as RNA gene + 5_prime_UTR_variant + 3_prime_UTR_variant + intron_variant .. reported only if none of the above + intergenic_variant .. reported only if none of the above + + + The annotation algorithm. + The algorithm checks if the variant falls in a region of a supported type. The + search is performed in the following order, until a match is found: + 1. idx_cds(gf_cds_t) - lookup CDS by position, create haplotypes, call consequences + 2. idx_utr(gf_utr_t) - check UTR hits + 3. idx_exon(gf_exon_t) - check for splice variants + 4. idx_tscript(tscript_t) - check for intronic variants, RNAs, etc. + + These regidx indexes are created by parsing a gff3 file as follows: + 1. create the array "ftr" of all UTR, CDS, exons. This will be + processed later and pruned based on transcript types we want to keep. + In the same go, create the hash "id2tr" of transcripts to keep + (based on biotype) which maps from transcript_id to a transcript. At + the same time also build the hash "gid2gene" which maps from gene_id to + gf_gene_t pointer. + + 2. build "idx_cds", "idx_tscript", "idx_utr" and "idx_exon" indexes. + Use only features from "ftr" which are present in "id2tr". + + 3. clean data that won't be needed anymore: ftr, id2tr, gid2gene. + + Data structures. + idx_cds, idx_utr, idx_exon, idx_tscript: + as described above, regidx structures for fast lookup of exons/transcripts + overlapping a region, the payload is a pointer to tscript.cds +*/ + +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include "bcftools.h" +#include "filter.h" +#include "regidx.h" +#include "kheap.h" +#include "smpl_ilist.h" +#include "rbuf.h" + +#ifndef __FUNCTION__ +# define __FUNCTION__ __func__ +#endif + +// Logic of the filters: include or exclude sites which match the filters? +#define FLT_INCLUDE 1 +#define FLT_EXCLUDE 2 + +// Definition of splice_region, splice_acceptor and splice_donor +#define N_SPLICE_DONOR 2 +#define N_SPLICE_REGION_EXON 3 +#define N_SPLICE_REGION_INTRON 8 + +// Ensembl ID format, e.g. +// ENST00000423372 for human .. ENST%011d +// ENSMUST00000120394 for mouse .. ENSMUST%011d +char ENSID_BUF[32], *ENSID_FMT = NULL; +static inline char *ENSID(uint32_t id) +{ + sprintf(ENSID_BUF,ENSID_FMT,id); + return ENSID_BUF; +} + + +#define N_REF_PAD 10 // number of bases to avoid boundary effects + +#define STRAND_REV 0 +#define STRAND_FWD 1 + +#define TRIM_NONE 0 +#define TRIM_5PRIME 1 +#define TRIM_3PRIME 2 + +// How to treat phased/unphased genotypes +#define PHASE_REQUIRE 0 // --phase r +#define PHASE_MERGE 1 // --phase m +#define PHASE_AS_IS 2 // --phase a +#define PHASE_SKIP 3 // --phase s +#define PHASE_NON_REF 4 // --phase R +#define PHASE_DROP_GT 5 // --samples - + +// Node types in the haplotype tree +#define HAP_CDS 0 +#define HAP_ROOT 1 +#define HAP_SSS 2 // start/stop/splice + +#define CSQ_PRINTED_UPSTREAM (1<<0) +#define CSQ_SYNONYMOUS_VARIANT (1<<1) +#define CSQ_MISSENSE_VARIANT (1<<2) +#define CSQ_STOP_LOST (1<<3) +#define CSQ_STOP_GAINED (1<<4) +#define CSQ_INFRAME_DELETION (1<<5) +#define CSQ_INFRAME_INSERTION (1<<6) +#define CSQ_FRAMESHIFT_VARIANT (1<<7) +#define CSQ_SPLICE_ACCEPTOR (1<<8) +#define CSQ_SPLICE_DONOR (1<<9) +#define CSQ_START_LOST (1<<10) +#define CSQ_SPLICE_REGION (1<<11) +#define CSQ_STOP_RETAINED (1<<12) +#define CSQ_UTR5 (1<<13) +#define CSQ_UTR3 (1<<14) +#define CSQ_NON_CODING (1<<15) +#define CSQ_INTRON (1<<16) +//#define CSQ_INTERGENIC (1<<17) +#define CSQ_INFRAME_ALTERING (1<<18) +#define CSQ_UPSTREAM_STOP (1<<19) // adds * in front of the csq string +#define CSQ_INCOMPLETE_CDS (1<<20) // to remove START/STOP in incomplete CDS, see ENSG00000173376/synon.vcf +#define CSQ_CODING_SEQUENCE (1<<21) // cannot tell exactly what it is, but it does affect the coding sequence + +// Haplotype-aware consequences, printed in one vcf record only, the rest has a reference @12345 +#define CSQ_COMPOUND (CSQ_SYNONYMOUS_VARIANT|CSQ_MISSENSE_VARIANT|CSQ_STOP_LOST|CSQ_STOP_GAINED| \ + CSQ_INFRAME_DELETION|CSQ_INFRAME_INSERTION|CSQ_FRAMESHIFT_VARIANT| \ + CSQ_START_LOST|CSQ_STOP_RETAINED|CSQ_INFRAME_ALTERING|CSQ_INCOMPLETE_CDS| \ + CSQ_UPSTREAM_STOP) +#define CSQ_START_STOP (CSQ_STOP_LOST|CSQ_STOP_GAINED|CSQ_STOP_RETAINED|CSQ_START_LOST) + +#define CSQ_PRN_STRAND(csq) ((csq)&CSQ_COMPOUND && !((csq)&(CSQ_SPLICE_ACCEPTOR|CSQ_SPLICE_DONOR|CSQ_SPLICE_REGION))) +#define CSQ_PRN_TSCRIPT (~(CSQ_INTRON|CSQ_NON_CODING)) +#define CSQ_PRN_BIOTYPE CSQ_NON_CODING + +// see kput_vcsq() +const char *csq_strings[] = +{ + NULL, + "synonymous", + "missense", + "stop_lost", + "stop_gained", + "inframe_deletion", + "inframe_insertion", + "frameshift", + "splice_acceptor", + "splice_donor", + "start_lost", + "splice_region", + "stop_retained", + "5_prime_utr", + "3_prime_utr", + "non_coding", + "intron", + "intergenic", + "inframe_altering", + NULL, + NULL, + "coding_sequence" +}; + + +// GFF line types +#define GFF_TSCRIPT_LINE 1 +#define GFF_GENE_LINE 2 + + +/* + Genomic features, for fast lookup by position to overlapping features +*/ +#define GF_coding_bit 6 +#define GF_is_coding(x) ((x) & (1<5I|121ACG>A+124TA>T" + + vcrec_t + single VCF record and csq tied to this record. (Haplotype can have multiple + consequences in several VCF records. Each record can have multiple consequences + from multiple haplotypes.) + + csq_t + a top-level consequence tied to a haplotype + + vbuf_t + pos2vbuf + VCF records with the same position clustered together for a fast lookup via pos2vbuf +*/ +typedef struct _vbuf_t vbuf_t; +typedef struct _vcsq_t vcsq_t; +struct _vcsq_t +{ + uint32_t strand:1, + type:31; // one of CSQ_* types + uint32_t trid; + uint32_t biotype; // one of GF_* types + char *gene; // gene name + bcf1_t *ref; // if type&CSQ_PRINTED_UPSTREAM, ref consequence "@1234" + kstring_t vstr; // variant string, eg 5TY>5I|121ACG>A+124TA>T +}; +typedef struct +{ + bcf1_t *line; + uint32_t *smpl; // bitmask of sample consequences with first/second haplotype interleaved + uint32_t nfmt:4, nvcsq:28, mvcsq; + vcsq_t *vcsq; // there can be multiple consequences for a single VCF record +} +vrec_t; +typedef struct +{ + uint32_t pos; + vrec_t *vrec; // vcf line that this csq is tied to; needed when printing haplotypes (hap_stage_vcf) + int idx; // 0-based index of the csq at the VCF line, for FMT/BCSQ + vcsq_t type; +} +csq_t; +struct _vbuf_t +{ + vrec_t **vrec; // buffer of VCF lines with the same position + int n, m; +}; +KHASH_MAP_INIT_INT(pos2vbuf, vbuf_t*) + + +/* + Structures related to haplotype-aware consequences in coding regions + + hap_node_t + node of a haplotype tree. Each transcript has one tree + + tscript_t + despite its general name, it is intended for coding transcripts only + + hap_t + hstack_t + for traversal of the haplotype tree and braking combined + consequences into independent parts +*/ +typedef struct _hap_node_t hap_node_t; +struct _hap_node_t +{ + char *seq; // cds segment [parent_node,this_node) + char *var; // variant "ref>alt" + uint32_t type:2, // HAP_ROOT or HAP_CDS + csq:30; // this node's consequence + int dlen; // alt minus ref length: <0 del, >0 ins, 0 substitution + uint32_t rbeg; // variant's VCF position (0-based, inclusive) + int32_t rlen; // variant's rlen; alen=rlen+dlen; fake for non CDS types + uint32_t sbeg; // variant's position on the spliced reference transcript (0-based, inclusive, N_REF_PAD not included) + uint32_t icds; // which exon does this node's variant overlaps + hap_node_t **child, *prev; // children haplotypes and previous coding node + int nchild, mchild; + bcf1_t *cur_rec, *rec; // current VCF record and node's VCF record + uint32_t nend; // number of haplotypes ending in this node + int *cur_child, mcur_child; // mapping from the allele to the currently active child + csq_t *csq_list; // list of haplotype's consequences, broken by position + int ncsq_list, mcsq_list; +}; +struct _tscript_t +{ + uint32_t id; // transcript id + uint32_t beg,end; // transcript's beg and end coordinate (ref strand, 0-based, inclusive) + uint32_t strand:1, // STRAND_REV or STRAND_FWD + ncds:31, // number of exons + mcds; + gf_cds_t **cds; // ordered list of exons + char *ref; // reference sequence, padded with N_REF_PAD bases on both ends + char *sref; // spliced reference sequence, padded with N_REF_PAD bases on both ends + hap_node_t *root; // root of the haplotype tree + hap_node_t **hap; // pointer to haplotype leaves, two for each sample + int nhap, nsref; // number of haplotypes and length of sref, including 2*N_REF_PAD + uint32_t trim:2, // complete, 5' or 3' trimmed, see TRIM_* types + type:30; // one of GF_* types + gf_gene_t *gene; +}; +static inline int cmp_tscript(tscript_t **a, tscript_t **b) +{ + return ( (*a)->end < (*b)->end ) ? 1 : 0; +} +KHEAP_INIT(trhp, tscript_t*, cmp_tscript) +typedef khp_trhp_t tr_heap_t; +typedef struct +{ + hap_node_t *node; // current node + int ichild; // current child in the active node + int dlen; // total dlen, from the root to the active node + size_t slen; // total sequence length, from the root to the active node +} +hstack_t; +typedef struct +{ + int mstack; + hstack_t *stack; + tscript_t *tr; // tr->ref: spliced transcript on ref strand + kstring_t sseq; // spliced haplotype sequence on ref strand + kstring_t tseq; // the variable part of translated haplotype transcript, coding strand + kstring_t tref; // the variable part of translated reference transcript, coding strand + uint32_t sbeg; // stack's sbeg, for cases first node's type is HAP_SSS + int upstream_stop; +} +hap_t; + + +/* + Helper structures, only for initialization + + ftr_t + temporary list of all exons, CDS, UTRs +*/ +KHASH_MAP_INIT_INT(int2tscript, tscript_t*) +KHASH_MAP_INIT_INT(int2int, int) +KHASH_MAP_INIT_INT(int2gene, gf_gene_t*) +typedef struct +{ + int type; // GF_CDS, GF_EXON, GF_5UTR, GF_3UTR + uint32_t beg; + uint32_t end; + uint32_t trid; + uint32_t strand:1; // STRAND_REV,STRAND_FWD + uint32_t phase:2; // 0, 1 or 2 + uint32_t iseq:29; +} +ftr_t; +typedef struct +{ + // all exons, CDS, UTRs + ftr_t *ftr; + int nftr, mftr; + + // mapping from transcript ensembl id to gene id + kh_int2gene_t *gid2gene; + + // mapping from transcript id to tscript, for quick CDS anchoring + kh_int2tscript_t *id2tr; + + // sequences + void *seq2int; + char **seq; + int nseq, mseq; + + // ignored biotypes + void *ignored_biotypes; +} +aux_t; + +typedef struct _args_t +{ + // the main regidx lookups, from chr:beg-end to overlapping features and + // index iterator + regidx_t *idx_cds, *idx_utr, *idx_exon, *idx_tscript; + regitr_t *itr; + + // temporary structures, deleted after initializtion + aux_t init; + + // text tab-delimited output (out) or vcf/bcf output (out_fh) + FILE *out; + htsFile *out_fh; + + // vcf + bcf_srs_t *sr; + bcf_hdr_t *hdr; + int hdr_nsmpl; // actual number of samples in the vcf, for bcf_update_format_values() + + // include or exclude sites which match the filters + filter_t *filter; + char *filter_str; + int filter_logic; // FLT_INCLUDE or FLT_EXCLUDE + + // samples to process + int sample_is_file; + char *sample_list; + smpl_ilist_t *smpl; + + char *outdir, **argv, *fa_fname, *gff_fname, *output_fname; + char *bcsq_tag; + int argc, output_type; + int phase, quiet, local_csq; + int ncsq_max, nfmt_bcsq; // maximum number of csq per site that can be accessed from FORMAT/BCSQ + int ncsq_small_warned; + + int rid; // current chromosome + tr_heap_t *active_tr; // heap of active transcripts for quick flushing + hap_t *hap; // transcript haplotype recursion + vbuf_t **vcf_buf; // buffered VCF lines to annotate with CSQ and flush + rbuf_t vcf_rbuf; // round buffer indexes to vcf_buf + kh_pos2vbuf_t *pos2vbuf; // fast lookup of buffered lines by position + tscript_t **rm_tr; // buffer of transcripts to clean + int nrm_tr, mrm_tr; + csq_t *csq_buf; // pool of csq not managed by hap_node_t, i.e. non-CDS csqs + int ncsq_buf, mcsq_buf; + + faidx_t *fai; + kstring_t str, str2; + int32_t *gt_arr, mgt_arr; +} +args_t; + +// AAA, AAC, ... +const char *gencode = "KNKNTTTTRSRSIIMIQHQHPPPPRRRRLLLLEDEDAAAAGGGGVVVV*Y*YSSSS*CWCLFLF"; +const uint8_t nt4[] = +{ + 4,4,4,4, 4,4,4,4, 4,4,4,4, 4,4,4,4, + 4,4,4,4, 4,4,4,4, 4,4,4,4, 4,4,4,4, + 4,4,4,4, 4,4,4,4, 4,4,4,4, 4,4,4,4, + 4,4,4,4, 4,4,4,4, 4,4,4,4, 4,4,4,4, + 4,0,4,1, 4,4,4,2, 4,4,4,4, 4,4,4,4, + 4,4,4,4, 3,4,4,4, 4,4,4,4, 4,4,4,4, + 4,0,4,1, 4,4,4,2, 4,4,4,4, 4,4,4,4, + 4,4,4,4, 3 +}; +const uint8_t cnt4[] = +{ + 4,4,4,4, 4,4,4,4, 4,4,4,4, 4,4,4,4, + 4,4,4,4, 4,4,4,4, 4,4,4,4, 4,4,4,4, + 4,4,4,4, 4,4,4,4, 4,4,4,4, 4,4,4,4, + 4,4,4,4, 4,4,4,4, 4,4,4,4, 4,4,4,4, + 4,3,4,2, 4,4,4,1, 4,4,4,4, 4,4,4,4, + 4,4,4,4, 0,4,4,4, 4,4,4,4, 4,4,4,4, + 4,3,4,2, 4,4,4,1, 4,4,4,4, 4,4,4,4, + 4,4,4,4, 0 +}; +#define dna2aa(x) gencode[ nt4[(uint8_t)(x)[0]]<<4 | nt4[(uint8_t)(x)[1]]<<2 | nt4[(uint8_t)(x)[2]] ] +#define cdna2aa(x) gencode[ cnt4[(uint8_t)(x)[2]]<<4 | cnt4[(uint8_t)(x)[1]]<<2 | cnt4[(uint8_t)(x)[0]] ] + +static const char *gf_strings_noncoding[] = +{ + "MT_rRNA", "MT_tRNA", "lincRNA", "miRNA", "misc_RNA", "rRNA", "snRNA", "snoRNA", "processed_transcript", + "antisense", "macro_lncRNA", "ribozyme", "sRNA", "scRNA", "scaRNA", "sense_intronic", "sense_overlapping", + "pseudogene", "processed_pseudogene", "artifact", "IG_pseudogene", "IG_C_pseudogene", "IG_J_pseudogene", + "IG_V_pseudogene", "TR_V_pseudogene", "TR_J_pseudogene", "MT_tRNA_pseudogene", "misc_RNA_pseudogene", + "miRNA_pseudogene", "ribozyme", "retained_intron", "retrotransposed", "Trna_pseudogene", "transcribed_processed_pseudogene", + "transcribed_unprocessed_pseudogene", "transcribed_unitary_pseudogene", "translated_unprocessed_pseudogene", + "translated_processed_pseudogene", "known_ncRNA", "unitary_pseudogene", "unprocessed_pseudogene", + "LRG_gene", "3_prime_overlapping_ncRNA", "disrupted_domain", "vaultRNA", "bidirectional_promoter_lncRNA", "ambiguous_orf" +}; +static const char *gf_strings_coding[] = { "protein_coding", "polymorphic_pseudogene", "IG_C", "IG_D", "IG_J", "IG_LV", "IG_V", "TR_C", "TR_D", "TR_J", "TR_V", "NMD", "non_stop_decay"}; +static const char *gf_strings_special[] = { "CDS", "exon", "3_prime_UTR", "5_prime_UTR" }; + +const char *gf_type2gff_string(int type) +{ + if ( !GF_is_coding(type) ) + { + if ( type < (1<init; + char c = chr_end[1]; + chr_end[1] = 0; + int iseq; + if ( khash_str2int_get(aux->seq2int, chr_beg, &iseq)!=0 ) + { + hts_expand(char*, aux->nseq+1, aux->mseq, aux->seq); + aux->seq[aux->nseq] = strdup(chr_beg); + iseq = khash_str2int_inc(aux->seq2int, aux->seq[aux->nseq]); + aux->nseq++; + assert( aux->nseq < 256 ); // see gf_gene_t.iseq + } + chr_end[1] = c; + return iseq; +} +static inline char *gff_skip(const char *line, char *ss) +{ + while ( *ss && *ss!='\t' ) ss++; + if ( !*ss ) error("[%s:%d %s] Could not parse the line: %s\n",__FILE__,__LINE__,__FUNCTION__,line); + return ss+1; +} +static inline void gff_parse_chr(const char *line, char **chr_beg, char **chr_end) +{ + char *se = (char*) line; + while ( *se && *se!='\t' ) se++; + if ( !*se ) error("[%s:%d %s] Could not parse the line: %s\n",__FILE__,__LINE__,__FUNCTION__,line); + *chr_beg = (char*) line; + *chr_end = se-1; +} +static inline char *gff_parse_beg_end(const char *line, char *ss, uint32_t *beg, uint32_t *end) +{ + char *se = ss; + *beg = strtol(ss, &se, 10) - 1; + if ( ss==se ) error("[%s:%d %s] Could not parse the line:\n\t%s\n\t%s\n",__FILE__,__LINE__,__FUNCTION__,line,ss); + ss = se+1; + *end = strtol(ss, &se, 10) - 1; + if ( ss==se ) error("[%s:%d %s] Could not parse the line: %s\n",__FILE__,__LINE__,__FUNCTION__,line); + return se+1; +} +static inline uint32_t gff_parse_id(const char *line, const char *needle, char *ss) +{ + ss = strstr(ss,needle); + if ( !ss ) error("[%s:%d %s] Could not parse the line, \"%s\" not present: %s\n",__FILE__,__LINE__,__FUNCTION__,needle,line); + ss += strlen(needle); + while ( *ss && !isdigit(*ss) ) ss++; + if ( !ss ) error("[%s:%d %s] Could not parse the line: %s\n",__FILE__,__LINE__,__FUNCTION__, line); + char *se; + uint32_t id = strtol(ss, &se, 10); + if ( ss==se ) error("[%s:%d %s] Could not parse the line: %s\n",__FILE__,__LINE__,__FUNCTION__, line); + if ( *se && *se!=';' && *se!='\t' ) error("[%s:%d %s] Could not parse the line: %s\n",__FILE__,__LINE__,__FUNCTION__,line); + assert( id <= 0xffffff ); // see gf_gene_t.id. Ensembl IDs are never that big in practice + return id; +} +static void gff_parse_ensid_fmt(const char *line, const char *needle, char *ss) +{ + ss = strstr(ss,needle); + if ( !ss ) error("[%s:%d %s] Could not parse the line, \"%s\" not present: %s\n",__FILE__,__LINE__,__FUNCTION__,needle,line); + ss += strlen(needle); + char *se = ss; + while ( *se && !isdigit(*se) ) se++; + kstring_t str = {0,0,0}; + kputsn(ss,se-ss,&str); + ss = se; + while ( *se && isdigit(*se) ) se++; + ksprintf(&str,"%%0%dd",(int)(se-ss)); + ENSID_FMT = str.s; +} +static inline int gff_parse_type(char *line) +{ + line = strstr(line,"ID="); + if ( !line ) return -1; + line += 3; + if ( !strncmp(line,"transcript:",11) ) return GFF_TSCRIPT_LINE; + else if ( !strncmp(line,"gene:",5) ) return GFF_GENE_LINE; + return -1; +} +static inline int gff_parse_biotype(char *_line) +{ + char *line = strstr(_line,"biotype="); + if ( !line ) return -1; + + line += 8; + switch (*line) + { + case 'p': + if ( !strncmp(line,"protein_coding",14) ) return GF_PROTEIN_CODING; + else if ( !strncmp(line,"pseudogene",10) ) return GF_PSEUDOGENE; + else if ( !strncmp(line,"processed_transcript",20) ) return GF_PROCESSED_TRANSCRIPT; + else if ( !strncmp(line,"processed_pseudogene",20) ) return GF_PROCESSED_PSEUDOGENE; + else if ( !strncmp(line,"polymorphic_pseudogene",22) ) return GF_POLYMORPHIC_PSEUDOGENE; + break; + case 'a': + if ( !strncmp(line,"artifact",8) ) return GF_ARTIFACT; + else if ( !strncmp(line,"antisense",9) ) return GF_ANTISENSE; + else if ( !strncmp(line,"ambiguous_orf",13) ) return GF_AMBIGUOUS_ORF; + break; + case 'I': + if ( !strncmp(line,"IG_C_gene",9) ) return GF_IG_C; + else if ( !strncmp(line,"IG_D_gene",9) ) return GF_IG_D; + else if ( !strncmp(line,"IG_J_gene",9) ) return GF_IG_J; + else if ( !strncmp(line,"IG_LV_gene",10) ) return GF_IG_LV; + else if ( !strncmp(line,"IG_V_gene",9) ) return GF_IG_V; + else if ( !strncmp(line,"IG_pseudogene",13) ) return GF_IG_PSEUDOGENE; + else if ( !strncmp(line,"IG_C_pseudogene",15) ) return GF_IG_C_PSEUDOGENE; + else if ( !strncmp(line,"IG_J_pseudogene",15) ) return GF_IG_J_PSEUDOGENE; + else if ( !strncmp(line,"IG_V_pseudogene",15) ) return GF_IG_V_PSEUDOGENE; + break; + case 'T': + if ( !strncmp(line,"TR_C_gene",9) ) return GF_TR_C; + else if ( !strncmp(line,"TR_D_gene",9) ) return GF_TR_D; + else if ( !strncmp(line,"TR_J_gene",9) ) return GF_TR_J; + else if ( !strncmp(line,"TR_V_gene",9) ) return GF_TR_V; + else if ( !strncmp(line,"TR_V_pseudogene",15) ) return GF_TR_V_PSEUDOGENE; + else if ( !strncmp(line,"TR_J_pseudogene",15) ) return GF_TR_J_PSEUDOGENE; + break; + case 'M': + if ( !strncmp(line,"Mt_tRNA_pseudogene",18) ) return GF_MT_tRNA_PSEUDOGENE; + else if ( !strncmp(line,"Mt_tRNA",7) ) return GF_MT_tRNA; + else if ( !strncmp(line,"Mt_rRNA",7) ) return GF_MT_tRNA; + break; + case 'l': + if ( !strncmp(line,"lincRNA",7) ) return GF_lincRNA; + break; + case 'm': + if ( !strncmp(line,"macro_lncRNA",12) ) return GF_macro_lncRNA; + else if ( !strncmp(line,"misc_RNA_pseudogene",19) ) return GF_misc_RNA_PSEUDOGENE; + else if ( !strncmp(line,"miRNA_pseudogene",16) ) return GF_miRNA_PSEUDOGENE; + else if ( !strncmp(line,"miRNA",5) ) return GF_miRNA; + else if ( !strncmp(line,"misc_RNA",8) ) return GF_MISC_RNA; + break; + case 'r': + if ( !strncmp(line,"rRNA",4) ) return GF_rRNA; + else if ( !strncmp(line,"ribozyme",8) ) return GF_RIBOZYME; + else if ( !strncmp(line,"retained_intron",15) ) return GF_RETAINED_INTRON; + else if ( !strncmp(line,"retrotransposed",15) ) return GF_RETROTRANSPOSED; + break; + case 's': + if ( !strncmp(line,"snRNA",5) ) return GF_snRNA; + else if ( !strncmp(line,"sRNA",4) ) return GF_sRNA; + else if ( !strncmp(line,"scRNA",5) ) return GF_scRNA; + else if ( !strncmp(line,"scaRNA",6) ) return GF_scaRNA; + else if ( !strncmp(line,"snoRNA",6) ) return GF_snoRNA; + else if ( !strncmp(line,"sense_intronic",14) ) return GF_SENSE_INTRONIC; + else if ( !strncmp(line,"sense_overlapping",17) ) return GF_SENSE_OVERLAPPING; + break; + case 't': + if ( !strncmp(line,"tRNA_pseudogene",15) ) return GF_tRNA_PSEUDOGENE; + else if ( !strncmp(line,"transcribed_processed_pseudogene",32) ) return GF_TRANSCRIBED_PROCESSED_PSEUDOGENE; + else if ( !strncmp(line,"transcribed_unprocessed_pseudogene",34) ) return GF_TRANSCRIBED_UNPROCESSED_PSEUDOGENE; + else if ( !strncmp(line,"transcribed_unitary_pseudogene",30) ) return GF_TRANSCRIBED_UNITARY_PSEUDOGENE; + else if ( !strncmp(line,"translated_unprocessed_pseudogene",33) ) return GF_TRANSLATED_UNPROCESSED_PSEUDOGENE; + else if ( !strncmp(line,"translated_processed_pseudogene",31) ) return GF_TRANSLATED_PROCESSED_PSEUDOGENE; + break; + case 'n': + if ( !strncmp(line,"nonsense_mediated_decay",23) ) return GF_NMD; + else if ( !strncmp(line,"non_stop_decay",14) ) return GF_NON_STOP_DECAY; + break; + case 'k': + if ( !strncmp(line,"known_ncrna",11) ) return GF_KNOWN_NCRNA; + break; + case 'u': + if ( !strncmp(line,"unitary_pseudogene",18) ) return GF_UNITARY_PSEUDOGENE; + else if ( !strncmp(line,"unprocessed_pseudogene",22) ) return GF_UNPROCESSED_PSEUDOGENE; + break; + case 'L': + if ( !strncmp(line,"LRG_gene",8) ) return GF_LRG_GENE; + break; + case '3': + if ( !strncmp(line,"3prime_overlapping_ncRNA",24) ) return GF_3PRIME_OVERLAPPING_ncRNA; + break; + case 'd': + if ( !strncmp(line,"disrupted_domain",16) ) return GF_DISRUPTED_DOMAIN; + break; + case 'v': + if ( !strncmp(line,"vaultRNA",8) ) return GF_vaultRNA; + break; + case 'b': + if ( !strncmp(line,"bidirectional_promoter_lncRNA",29) ) return GF_BIDIRECTIONAL_PROMOTER_lncRNA; + break; + } + return 0; +} +static inline int gff_ignored_biotype(args_t *args, char *ss) +{ + ss = strstr(ss,"biotype="); + if ( !ss ) return 0; + + ss += 8; + char *se = ss, tmp; + while ( *se && *se!=';' ) se++; + tmp = *se; + *se = 0; + + char *key = ss; + int n = 0; + if ( khash_str2int_get(args->init.ignored_biotypes, ss, &n)!=0 ) key = strdup(ss); + khash_str2int_set(args->init.ignored_biotypes, key, n+1); + + *se = tmp; + return 1; +} +gf_gene_t *gene_init(aux_t *aux, uint32_t gene_id) +{ + khint_t k = kh_get(int2gene, aux->gid2gene, (int)gene_id); + gf_gene_t *gene = (k == kh_end(aux->gid2gene)) ? NULL : kh_val(aux->gid2gene, k); + if ( !gene ) + { + gene = (gf_gene_t*) calloc(1,sizeof(gf_gene_t)); + int ret; + k = kh_put(int2gene, aux->gid2gene, (int)gene_id, &ret); + kh_val(aux->gid2gene,k) = gene; + } + return gene; +} +void gff_parse_transcript(args_t *args, const char *line, char *ss, ftr_t *ftr) +{ + aux_t *aux = &args->init; + int biotype = gff_parse_biotype(ss); + if ( biotype <= 0 ) + { + if ( !gff_ignored_biotype(args, ss) && args->quiet<2 ) fprintf(stderr,"ignored transcript: %s\n",line); + return; + } + + // create a mapping from transcript_id to gene_id + uint32_t trid = gff_parse_id(line, "ID=transcript:", ss); + uint32_t gene_id = gff_parse_id(line, "Parent=gene:", ss); + + if ( !ENSID_FMT ) gff_parse_ensid_fmt(line, "ID=transcript:", ss); // id prefix different across species + + tscript_t *tr = (tscript_t*) calloc(1,sizeof(tscript_t)); + tr->id = trid; + tr->strand = ftr->strand; + tr->gene = gene_init(aux, gene_id); + tr->type = biotype; + tr->beg = ftr->beg; + tr->end = ftr->end; + + khint_t k; + int ret; + k = kh_put(int2tscript, aux->id2tr, (int)trid, &ret); + kh_val(aux->id2tr,k) = tr; +} +void gff_parse_gene(args_t *args, const char *line, char *ss, char *chr_beg, char *chr_end, ftr_t *ftr) +{ + int biotype = gff_parse_biotype(ss); + if ( biotype <= 0 ) + { + if ( !gff_ignored_biotype(args, ss) && args->quiet<2 ) fprintf(stderr,"ignored gene: %s\n",line); + return; + } + + aux_t *aux = &args->init; + + // substring search for "ID=gene:ENSG00000437963" + uint32_t gene_id = gff_parse_id(line, "ID=gene:", ss); + gf_gene_t *gene = gene_init(aux, gene_id); + assert( !gene->name ); // the gene_id should be unique + + gene->iseq = feature_set_seq(args, chr_beg,chr_end); + + // substring search for "Name=OR4F5" + ss = strstr(chr_end+2,"Name="); + if ( !ss ) error("Could not parse the line, \"Name=\" not present: %s\n", line); + ss += 5; + char *se = ss; + while ( *se && *se!=';' && !isspace(*se) ) se++; + gene->name = (char*) malloc(se-ss+1); + memcpy(gene->name,ss,se-ss); + gene->name[se-ss] = 0; +} +int gff_parse(args_t *args, char *line, ftr_t *ftr) +{ + // - skip empty lines and commented lines + // - columns + // 1. chr + // 2. + // 3. CDS, transcript, gene, ... + // 4-5. beg,end + // 6. + // 7. strand + // 8. phase + // 9. Parent=transcript:ENST(\d+);ID=... etc + + char *ss = line; + if ( !*ss ) return -1; // skip blank lines + if ( *ss=='#' ) return -1; // skip comments + + char *chr_beg, *chr_end; + gff_parse_chr(line, &chr_beg, &chr_end); + ss = gff_skip(line, chr_end + 2); + + // 3. column: is this a CDS, transcript, gene, etc. + if ( !strncmp("exon\t",ss,5) ) { ftr->type = GF_EXON; ss += 5; } + else if ( !strncmp("CDS\t",ss,4) ) { ftr->type = GF_CDS; ss += 4; } + else if ( !strncmp("three_prime_UTR\t",ss,16) ) { ftr->type = GF_UTR3; ss += 16; } + else if ( !strncmp("five_prime_UTR\t",ss,15) ) { ftr->type = GF_UTR5; ss += 15; } + else + { + ss = gff_skip(line, ss); + ss = gff_parse_beg_end(line, ss, &ftr->beg,&ftr->end); + ss = gff_skip(line, ss); + int type = gff_parse_type(ss); + if ( type!=GFF_TSCRIPT_LINE && type!=GFF_GENE_LINE ) + { + // we ignore these, debug print to see new types: + ss = strstr(ss,"ID="); + if ( !ss ) return -1; // no ID, ignore the line + if ( !strncmp("chromosome",ss+3,10) ) return -1; + if ( !strncmp("supercontig",ss+3,11) ) return -1; + if ( args->quiet<2 ) fprintf(stderr,"ignored: %s\n", line); + return -1; + } + + // 7. column: strand + if ( *ss == '+' ) ftr->strand = STRAND_FWD; + else if ( *ss == '-' ) ftr->strand = STRAND_REV; + else error("Unknown strand: %c .. %s\n", *ss,ss); + + if ( type==GFF_TSCRIPT_LINE ) + gff_parse_transcript(args, line, ss, ftr); + else + gff_parse_gene(args, line, ss, chr_beg, chr_end, ftr); + + return -1; + } + ss = gff_parse_beg_end(line, ss, &ftr->beg,&ftr->end); + ss = gff_skip(line, ss); + + // 7. column: strand + if ( *ss == '+' ) ftr->strand = STRAND_FWD; + else if ( *ss == '-' ) ftr->strand = STRAND_REV; + else { if ( args->quiet<2 ) fprintf(stderr,"Skipping unknown strand: %c\n", *ss); return -1; } + ss += 2; + + // 8. column: phase (codon offset) + if ( *ss == '0' ) ftr->phase = 0; + else if ( *ss == '1' ) ftr->phase = 1; + else if ( *ss == '2' ) ftr->phase = 2; + else if ( *ss == '.' ) ftr->phase = 0; // exons do not have phase + else { if ( args->quiet<2 ) fprintf(stderr,"Skipping unknown phase: %c, %s\n", *ss, line); return -1; } + ss += 2; + + // substring search for "Parent=transcript:ENST00000437963" + ftr->trid = gff_parse_id(line, "Parent=transcript:", ss); + ftr->iseq = feature_set_seq(args, chr_beg,chr_end); + return 0; +} + +static int cmp_cds_ptr(const void *a, const void *b) +{ + // comparison function for qsort of transcripts's CDS + if ( (*((gf_cds_t**)a))->beg < (*((gf_cds_t**)b))->beg ) return -1; + if ( (*((gf_cds_t**)a))->beg > (*((gf_cds_t**)b))->beg ) return 1; + return 0; +} + +static inline void chr_beg_end(aux_t *aux, int iseq, char **chr_beg, char **chr_end) +{ + *chr_beg = *chr_end = aux->seq[iseq]; + while ( (*chr_end)[1] ) (*chr_end)++; +} +tscript_t *tscript_init(aux_t *aux, uint32_t trid) +{ + khint_t k = kh_get(int2tscript, aux->id2tr, (int)trid); + tscript_t *tr = (k == kh_end(aux->id2tr)) ? NULL : kh_val(aux->id2tr, k); + assert( tr ); + return tr; +} +void register_cds(args_t *args, ftr_t *ftr) +{ + // Make the CDS searchable via idx_cds. Note we do not malloc tr->cds just yet. + // ftr is the result of parsing a gff CDS line + aux_t *aux = &args->init; + + tscript_t *tr = tscript_init(aux, ftr->trid); + if ( tr->strand != ftr->strand ) error("Conflicting strand in transcript %"PRIu32" .. %d vs %d\n",ftr->trid,tr->strand,ftr->strand); + + gf_cds_t *cds = (gf_cds_t*) malloc(sizeof(gf_cds_t)); + cds->tr = tr; + cds->beg = ftr->beg; + cds->len = ftr->end - ftr->beg + 1; + cds->icds = 0; // to keep valgrind on mac happy + cds->phase = ftr->phase; + + hts_expand(gf_cds_t*,tr->ncds+1,tr->mcds,tr->cds); + tr->cds[tr->ncds++] = cds; +} +void register_utr(args_t *args, ftr_t *ftr) +{ + aux_t *aux = &args->init; + gf_utr_t *utr = (gf_utr_t*) malloc(sizeof(gf_utr_t)); + utr->which = ftr->type==GF_UTR3 ? prime3 : prime5; + utr->beg = ftr->beg; + utr->end = ftr->end; + utr->tr = tscript_init(aux, ftr->trid); + + char *chr_beg, *chr_end; + chr_beg_end(&args->init, utr->tr->gene->iseq, &chr_beg, &chr_end); + regidx_push(args->idx_utr, chr_beg,chr_end, utr->beg,utr->end, &utr); +} +void register_exon(args_t *args, ftr_t *ftr) +{ + aux_t *aux = &args->init; + gf_exon_t *exon = (gf_exon_t*) malloc(sizeof(gf_exon_t)); + exon->beg = ftr->beg; + exon->end = ftr->end; + exon->tr = tscript_init(aux, ftr->trid); + + char *chr_beg, *chr_end; + chr_beg_end(&args->init, exon->tr->gene->iseq, &chr_beg, &chr_end); + regidx_push(args->idx_exon, chr_beg,chr_end, exon->beg - N_SPLICE_REGION_INTRON, exon->end + N_SPLICE_REGION_INTRON, &exon); +} + +void tscript_init_cds(args_t *args) +{ + aux_t *aux = &args->init; + + // Sort CDS in all transcripts, set offsets, check their phase, length, create index (idx_cds) + khint_t k; + for (k=0; kid2tr); k++) + { + if ( !kh_exist(aux->id2tr, k) ) continue; + tscript_t *tr = (tscript_t*) kh_val(aux->id2tr, k); + + // position-to-tscript lookup + char *chr_beg, *chr_end; + chr_beg_end(aux, tr->gene->iseq, &chr_beg, &chr_end); + regidx_push(args->idx_tscript, chr_beg, chr_end, tr->beg, tr->end, &tr); + + if ( !tr->ncds ) continue; // transcript with no CDS + + // sort CDs + qsort(tr->cds, tr->ncds, sizeof(gf_cds_t*), cmp_cds_ptr); + + // trim non-coding start + int i, len = 0; + if ( tr->strand==STRAND_FWD ) + { + if ( tr->cds[0]->phase ) tr->trim |= TRIM_5PRIME; + tr->cds[0]->beg += tr->cds[0]->phase; + tr->cds[0]->len -= tr->cds[0]->phase; + tr->cds[0]->phase = 0; + + // sanity check phase + for (i=0; incds; i++) + { + int phase = tr->cds[i]->phase ? 3 - tr->cds[i]->phase : 0; + if ( phase!=len%3) + error("GFF3 assumption failed for transcript %s, CDS=%d: phase!=len%%3 (phase=%d, len=%d)\n",ENSID(tr->id),tr->cds[i]->beg+1,phase,len); + assert( phase == len%3 ); + len += tr->cds[i]->len; + } + } + else + { + // Check that the phase is not bigger than CDS length. Curiously, this can really happen, + // see Mus_musculus.GRCm38.85.gff3.gz, transcript:ENSMUST00000163141 + // todo: the same for the fwd strand + i = tr->ncds - 1; + int phase = tr->cds[i]->phase; + if ( phase ) tr->trim |= TRIM_5PRIME; + while ( i>=0 && phase > tr->cds[i]->len ) + { + phase -= tr->cds[i]->len; + tr->cds[i]->phase = 0; + tr->cds[i]->len = 0; + i--; + } + tr->cds[i]->len -= tr->cds[i]->phase; + tr->cds[i]->phase = 0; + + // sanity check phase + for (i=tr->ncds-1; i>=0; i--) + { + int phase = tr->cds[i]->phase ? 3 - tr->cds[i]->phase : 0; + if ( phase!=len%3) + error("GFF3 assumption failed for transcript %s, CDS=%d: phase!=len%%3 (phase=%d, len=%d)\n",ENSID(tr->id),tr->cds[i]->beg+1,phase,len); + len += tr->cds[i]->len; + } + } + + // set len. At the same check that CDS within a transcript do not overlap + len = 0; + for (i=0; incds; i++) + { + tr->cds[i]->icds = i; + len += tr->cds[i]->len; + if ( !i ) continue; + + gf_cds_t *a = tr->cds[i-1]; + gf_cds_t *b = tr->cds[i]; + if ( a->beg + a->len - 1 >= b->beg ) + error("Error: CDS overlap in the transcript %"PRIu32": %"PRIu32"-%"PRIu32" and %"PRIu32"-%"PRIu32"\n", + kh_key(aux->id2tr, k), a->beg+1,a->beg+a->len, b->beg+1,b->beg+b->len); + } + if ( len%3 != 0 ) + { + // There are 13k transcripts with incomplete 3' CDS. See for example ENST00000524289 + // http://sep2015.archive.ensembl.org/Homo_sapiens/Transcript/Sequence_cDNA?db=core;g=ENSG00000155868;r=5:157138846-157159019;t=ENST00000524289 + // Also, the incomplete CDS can be too short (1 or 2bp), so it is not enough to trim the last one. + + tr->trim |= TRIM_3PRIME; + if ( tr->strand==STRAND_FWD ) + { + i = tr->ncds - 1; + while ( i>=0 && len%3 ) + { + int dlen = tr->cds[i]->len >= len%3 ? len%3 : tr->cds[i]->len; + tr->cds[i]->len -= dlen; + len -= dlen; + i--; + } + } + else + { + i = 0; + while ( incds && len%3 ) + { + int dlen = tr->cds[i]->len >= len%3 ? len%3 : tr->cds[i]->len; + tr->cds[i]->len -= dlen; + tr->cds[i]->beg += dlen; + len -= dlen; + i++; + } + } + } + + // set CDS offsets and insert into regidx + len=0; + for (i=0; incds; i++) + { + tr->cds[i]->pos = len; + len += tr->cds[i]->len; + regidx_push(args->idx_cds, chr_beg,chr_end, tr->cds[i]->beg,tr->cds[i]->beg+tr->cds[i]->len-1, &tr->cds[i]); + } + } +} + +void regidx_free_gf(void *payload) { free(*((gf_cds_t**)payload)); } +void regidx_free_tscript(void *payload) { tscript_t *tr = *((tscript_t**)payload); free(tr->cds); free(tr); } + +void init_gff(args_t *args) +{ + aux_t *aux = &args->init; + aux->seq2int = khash_str2int_init(); // chrom's numeric id + aux->gid2gene = kh_init(int2gene); // gene id to gf_gene_t, for idx_gene + aux->id2tr = kh_init(int2tscript); // transcript id to tscript_t + args->idx_tscript = regidx_init(NULL, NULL, regidx_free_tscript, sizeof(tscript_t*), NULL); + aux->ignored_biotypes = khash_str2int_init(); + + // parse gff + kstring_t str = {0,0,0}; + htsFile *fp = hts_open(args->gff_fname,"r"); + if ( !fp ) error("Failed to read %s\n", args->gff_fname); + while ( hts_getline(fp, KS_SEP_LINE, &str) > 0 ) + { + hts_expand(ftr_t, aux->nftr+1, aux->mftr, aux->ftr); + int ret = gff_parse(args, str.s, aux->ftr + aux->nftr); + if ( !ret ) aux->nftr++; + } + free(str.s); + if ( hts_close(fp)!=0 ) error("Close failed: %s\n", args->gff_fname); + + + // process gff information: connect CDS and exons to transcripts + args->idx_cds = regidx_init(NULL, NULL, regidx_free_gf, sizeof(gf_cds_t*), NULL); + args->idx_utr = regidx_init(NULL, NULL, regidx_free_gf, sizeof(gf_utr_t*), NULL); + args->idx_exon = regidx_init(NULL, NULL, regidx_free_gf, sizeof(gf_exon_t*), NULL); + args->itr = regitr_init(NULL); + + int i; + for (i=0; inftr; i++) + { + ftr_t *ftr = &aux->ftr[i]; + + // check whether to keep this feature: is there a mapping trid -> gene_id -> gene? + khint_t k = kh_get(int2tscript, aux->id2tr, (int)ftr->trid); + if ( k==kh_end(aux->id2tr) ) continue; // no such transcript + + tscript_t *tr = kh_val(aux->id2tr,k); + if ( !tr->gene->name ) + { + // not a supported biotype (e.g. gene:pseudogene, transcript:processed_transcript) + regidx_free_tscript(&tr); + kh_del(int2tscript, aux->id2tr,k); + continue; + } + + // populate regidx by category: + // ftr->type .. GF_CDS, GF_EXON, GF_UTR3, GF_UTR5 + // gene->type .. GF_PROTEIN_CODING, GF_MT_rRNA, GF_IG_C, ... + if ( ftr->type==GF_CDS ) register_cds(args, ftr); + else if ( ftr->type==GF_EXON ) register_exon(args, ftr); + else if ( ftr->type==GF_UTR5 ) register_utr(args, ftr); + else if ( ftr->type==GF_UTR3 ) register_utr(args, ftr); + else + error("something: %s\t%d\t%d\t%s\t%s\n", aux->seq[ftr->iseq],ftr->beg+1,ftr->end+1,ENSID(ftr->trid),gf_type2gff_string(ftr->type)); + } + tscript_init_cds(args); + + if ( !args->quiet ) + { + fprintf(stderr,"Indexed %d transcripts, %d exons, %d CDSs, %d UTRs\n", + regidx_nregs(args->idx_tscript), + regidx_nregs(args->idx_exon), + regidx_nregs(args->idx_cds), + regidx_nregs(args->idx_utr)); + } + + free(aux->ftr); + khash_str2int_destroy_free(aux->seq2int); + // keeping only to destroy the genes at the end: kh_destroy(int2gene,aux->gid2gene); + kh_destroy(int2tscript,aux->id2tr); + free(aux->seq); + + if ( args->quiet<2 && khash_str2int_size(aux->ignored_biotypes) ) + { + khash_t(str2int) *ign = (khash_t(str2int)*)aux->ignored_biotypes; + fprintf(stderr,"Ignored the following biotypes:\n"); + for (i = kh_begin(ign); i < kh_end(ign); i++) + { + if ( !kh_exist(ign,i)) continue; + fprintf(stderr,"\t%dx\t.. %s\n", kh_value(ign,i), kh_key(ign,i)); + } + } + khash_str2int_destroy_free(aux->ignored_biotypes); +} + +void init_data(args_t *args) +{ + args->nfmt_bcsq = 1 + (args->ncsq_max - 1) / 32; + + if ( !args->quiet ) fprintf(stderr,"Parsing %s ...\n", args->gff_fname); + init_gff(args); + + args->rid = -1; + + if ( args->filter_str ) + args->filter = filter_init(args->hdr, args->filter_str); + + args->fai = fai_load(args->fa_fname); + if ( !args->fai ) error("Failed to load the fai index: %s\n", args->fa_fname); + + args->pos2vbuf = kh_init(pos2vbuf); + args->active_tr = khp_init(trhp); + args->hap = (hap_t*) calloc(1,sizeof(hap_t)); + + // init samples + if ( !bcf_hdr_nsamples(args->hdr) ) args->phase = PHASE_DROP_GT; + if ( args->sample_list && !strcmp("-",args->sample_list) ) + { + // ignore all samples + if ( args->output_type==FT_TAB_TEXT ) + { + // significant speedup for plain VCFs + bcf_hdr_set_samples(args->hdr,NULL,0); + } + args->phase = PHASE_DROP_GT; + } + else + args->smpl = smpl_ilist_init(args->hdr, args->sample_list, args->sample_is_file, SMPL_STRICT); + args->hdr_nsmpl = args->phase==PHASE_DROP_GT ? 0 : bcf_hdr_nsamples(args->hdr); + + if ( args->output_type==FT_TAB_TEXT ) + { + args->out = args->output_fname ? fopen(args->output_fname,"w") : stdout; + if ( !args->out ) error("Failed to open %s: %s\n", args->output_fname,strerror(errno)); + + fprintf(args->out,"# This file was produced by: bcftools +csq(%s+htslib-%s)\n", bcftools_version(),hts_version()); + fprintf(args->out,"# The command line was:\tbcftools +%s", args->argv[0]); + int i; + for (i=1; iargc; i++) + fprintf(args->out," %s",args->argv[i]); + fprintf(args->out,"\n"); + fprintf(args->out,"# LOG\t[2]Message\n"); + fprintf(args->out,"# CSQ"); i = 1; + fprintf(args->out,"\t[%d]Sample", ++i); + fprintf(args->out,"\t[%d]Haplotype", ++i); + fprintf(args->out,"\t[%d]Chromosome", ++i); + fprintf(args->out,"\t[%d]Position", ++i); + fprintf(args->out,"\t[%d]Consequence", ++i); + fprintf(args->out,"\n"); + } + else + { + args->out_fh = hts_open(args->output_fname? args->output_fname : "-",hts_bcf_wmode(args->output_type)); + if ( args->out_fh == NULL ) error("Can't write to %s: %s\n", args->output_fname? args->output_fname : "standard output", strerror(errno)); + bcf_hdr_append_version(args->hdr,args->argc,args->argv,"bcftools/csq"); + bcf_hdr_printf(args->hdr,"##INFO=",args->bcsq_tag, args->local_csq ? "Local" : "Haplotype-aware"); + if ( args->hdr_nsmpl ) + bcf_hdr_printf(args->hdr,"##FORMAT=",args->bcsq_tag); + bcf_hdr_write(args->out_fh, args->hdr); + } + if ( !args->quiet ) fprintf(stderr,"Calling...\n"); +} + +void destroy_data(args_t *args) +{ + regidx_destroy(args->idx_cds); + regidx_destroy(args->idx_utr); + regidx_destroy(args->idx_exon); + regidx_destroy(args->idx_tscript); + regitr_destroy(args->itr); + + khint_t k,i,j; + for (k=0; kinit.gid2gene); k++) + { + if ( !kh_exist(args->init.gid2gene, k) ) continue; + gf_gene_t *gene = (gf_gene_t*) kh_val(args->init.gid2gene, k); + free(gene->name); + free(gene); + } + kh_destroy(int2gene,args->init.gid2gene); + + if ( args->filter ) + filter_destroy(args->filter); + + khp_destroy(trhp,args->active_tr); + kh_destroy(pos2vbuf,args->pos2vbuf); + if ( args->smpl ) smpl_ilist_destroy(args->smpl); + int ret; + if ( args->out_fh ) + ret = hts_close(args->out_fh); + else + ret = fclose(args->out); + if ( ret ) error("Error: close failed .. %s\n", args->output_fname?args->output_fname:"stdout"); + for (i=0; ivcf_rbuf.m; i++) + { + vbuf_t *vbuf = args->vcf_buf[i]; + if ( !vbuf ) continue; + for (j=0; jm; j++) + { + if ( !vbuf->vrec[j] ) continue; + if ( vbuf->vrec[j]->line ) bcf_destroy(vbuf->vrec[j]->line); + free(vbuf->vrec[j]->smpl); + free(vbuf->vrec[j]->vcsq); + free(vbuf->vrec[j]); + } + free(vbuf->vrec); + free(vbuf); + } + free(args->vcf_buf); + free(args->rm_tr); + free(args->csq_buf); + free(args->hap->stack); + free(args->hap->sseq.s); + free(args->hap->tseq.s); + free(args->hap->tref.s); + free(args->hap); + fai_destroy(args->fai); + free(args->gt_arr); + free(args->str.s); + free(args->str2.s); + free(ENSID_FMT); +} + +/* + The splice_* functions are for consquences around splice sites: start,stop,splice_* + */ +#define SPLICE_VAR_REF 0 // ref: ACGT>ACGT, csq not applicable, skip completely +#define SPLICE_OUTSIDE 1 // splice acceptor or similar; csq set and is done, does not overlap the region +#define SPLICE_INSIDE 2 // overlaps coding region; csq can be set but coding prediction is needed +#define SPLICE_OVERLAP 3 // indel overlaps region boundary, csq set but could not determine csq +typedef struct +{ + tscript_t *tr; + struct { + int32_t pos, rlen, alen; + char *ref, *alt; + bcf1_t *rec; + } vcf; + uint16_t check_acceptor:1, // check distance from exon start (fwd) or end (rev) + check_start:1, // this is the first coding exon (relative to transcript orientation), check first (fwd) or last (rev) codon + check_stop:1, // this is the last coding exon (relative to transcript orientation), check last (fwd) or first (rev) codon + check_donor:1, // as with check_acceptor + check_region_beg:1, // do/don't check for splices at this end, eg. in the first or last exon + check_region_end:1, // + check_utr:1, // check splice sites (acceptor/donor/region_*) only if not in utr + set_refalt:1; // set kref,kalt, if set, check also for synonymous events + uint32_t csq; + int tbeg, tend; // number of trimmed bases from beg and end of ref,alt allele + uint32_t ref_beg, // ref coordinates with spurious bases removed, ACC>AC can become AC>A or CC>C, whichever gives + ref_end; // a more conservative csq (the first and last base in kref.s) + kstring_t kref, kalt; // trimmed alleles, set only with SPLICE_OLAP +} +splice_t; +void splice_init(splice_t *splice, bcf1_t *rec) +{ + memset(splice,0,sizeof(*splice)); + splice->vcf.rec = rec; + splice->vcf.pos = rec->pos; + splice->vcf.rlen = rec->rlen; + splice->vcf.ref = rec->d.allele[0]; +} +static inline void splice_build_hap(splice_t *splice, uint32_t beg, int len) +{ + // len>0 .. beg is the first base, del filled from right + // len<0 .. beg is the last base, del filled from left + + int rlen, alen, rbeg, abeg; // first base to include (ref coordinates) + if ( len<0 ) + { + rlen = alen = -len; + rbeg = beg - rlen + 1; + int dlen = splice->vcf.alen - splice->vcf.rlen; + if ( dlen<0 && beg < splice->ref_end ) // incomplete del, beg is in the middle + dlen += splice->ref_end - beg; + abeg = rbeg + dlen; + } + else + { + rbeg = abeg = beg; + rlen = alen = len; + // check for incomplete del as above?? + } + +#define XDBG 0 +#if XDBG +fprintf(stderr,"build_hap: rbeg=%d + %d abeg=%d \n",rbeg,rlen,abeg); +#endif + splice->kref.l = 0; + splice->kalt.l = 0; + + // add the part before vcf.ref, in the vcf.ref and after vcf.ref + int roff; // how many vcf.ref bases already used + if ( rbeg < splice->vcf.pos ) + { + assert( splice->tr->beg <= rbeg ); // this can be extended thanks to N_REF_PAD + kputsn(splice->tr->ref + N_REF_PAD + rbeg - splice->tr->beg, splice->vcf.pos - rbeg, &splice->kref); + roff = 0; + } + else + roff = rbeg - splice->vcf.pos; +#if XDBG +fprintf(stderr,"r1: %s roff=%d\n",splice->kref.s,roff); +#endif + + if ( roff < splice->vcf.rlen && splice->kref.l < rlen ) + { + int len = splice->vcf.rlen - roff; // len still available in vcf.ref + if ( len > rlen - splice->kref.l ) len = rlen - splice->kref.l; // how much of ref allele is still needed + kputsn(splice->vcf.ref + roff, len, &splice->kref); + } +#if XDBG +fprintf(stderr,"r2: %s\n",splice->kref.s); +#endif + + uint32_t end = splice->vcf.pos + splice->vcf.rlen; // position just after the ref allele + if ( splice->kref.l < rlen ) + { + if ( end + rlen - splice->kref.l - 1 > splice->tr->end ) // trim, the requested sequence is too long (could be extended, see N_REF_PAD) + rlen -= end + rlen - splice->kref.l - 1 - splice->tr->end; + if ( splice->kref.l < rlen ) + kputsn(splice->tr->ref + N_REF_PAD + end - splice->tr->beg, rlen - splice->kref.l, &splice->kref); + } +#if XDBG +fprintf(stderr,"r3: %s\n",splice->kref.s); +#endif + + + int aoff; + if ( abeg < splice->vcf.pos ) + { + assert( splice->tr->beg <= abeg ); + kputsn(splice->tr->ref + N_REF_PAD + abeg - splice->tr->beg, splice->vcf.pos - abeg, &splice->kalt); + aoff = 0; + } + else + aoff = abeg - splice->vcf.pos; +#if XDBG +fprintf(stderr,"a1: %s aoff=%d\n",splice->kalt.s,aoff); +#endif + + if ( aoff < splice->vcf.alen && splice->kalt.l < alen ) + { + int len = splice->vcf.alen - aoff; // len still available in vcf.alt + if ( len > alen - splice->kalt.l ) len = alen - splice->kalt.l; // how much of alt allele is still needed + kputsn(splice->vcf.alt + aoff, len, &splice->kalt); + aoff -= len; + } + if ( aoff < 0 ) aoff = 0; + else aoff--; +#if XDBG +fprintf(stderr,"a2: %s aoff=%d\n",splice->kalt.s,aoff); +#endif + + end = splice->vcf.pos + splice->vcf.rlen; // position just after the ref allele + if ( splice->kalt.l < alen ) + { + if ( end + alen + aoff - splice->kalt.l - 1 > splice->tr->end ) // trim, the requested sequence is too long + alen -= end + alen + aoff - splice->kalt.l - 1 - splice->tr->end; + if ( alen > 0 && alen > splice->kalt.l ) + kputsn(splice->tr->ref + aoff + N_REF_PAD + end - splice->tr->beg, alen - splice->kalt.l, &splice->kalt); + } +#if XDBG +fprintf(stderr,"a3: %s\n",splice->kalt.s); +fprintf(stderr," [%s]\n [%s]\n\n",splice->kref.s,splice->kalt.s); +#endif +} +void csq_stage(args_t *args, csq_t *csq, bcf1_t *rec); +static inline int csq_stage_utr(args_t *args, regitr_t *itr, bcf1_t *rec, uint32_t trid) +{ + while ( regitr_overlap(itr) ) + { + gf_utr_t *utr = regitr_payload(itr, gf_utr_t*); + tscript_t *tr = utr->tr; + if ( tr->id != trid ) continue; + csq_t csq; + memset(&csq, 0, sizeof(csq_t)); + csq.pos = rec->pos; + csq.type.type = utr->which==prime5 ? CSQ_UTR5 : CSQ_UTR3; + csq.type.biotype = tr->type; + csq.type.strand = tr->strand; + csq.type.trid = tr->id; + csq.type.gene = tr->gene->name; + csq_stage(args, &csq, rec); + return csq.type.type; + } + return 0; +} +static inline void csq_stage_splice(args_t *args, bcf1_t *rec, tscript_t *tr, uint32_t type) +{ +#if XDBG +fprintf(stderr,"csq_stage_splice %d: type=%d\n",rec->pos+1,type); +#endif + if ( !type ) return; + csq_t csq; + memset(&csq, 0, sizeof(csq_t)); + csq.pos = rec->pos; + csq.type.type = type; + csq.type.biotype = tr->type; + csq.type.strand = tr->strand; + csq.type.trid = tr->id; + csq.type.gene = tr->gene->name; + csq_stage(args, &csq, rec); +} +static inline int splice_csq_ins(args_t *args, splice_t *splice, uint32_t ex_beg, uint32_t ex_end) +{ + // coordinates that matter for consequences, eg AC>ACG trimmed to C>CG, 1bp + // before and after the inserted bases + if ( splice->tbeg || splice->vcf.ref[0]!=splice->vcf.alt[0] ) + { + splice->ref_beg = splice->vcf.pos + splice->tbeg - 1; + splice->ref_end = splice->vcf.pos + splice->vcf.rlen - splice->tend; + } + else + { + if ( splice->tend ) splice->tend--; + splice->ref_beg = splice->vcf.pos; + splice->ref_end = splice->vcf.pos + splice->vcf.rlen - splice->tend; + } +#if XDBG +fprintf(stderr,"ins: %s>%s .. ex=%d,%d beg,end=%d,%d tbeg,tend=%d,%d check_utr=%d start,stop,beg,end=%d,%d,%d,%d\n", splice->vcf.ref,splice->vcf.alt,ex_beg,ex_end,splice->ref_beg,splice->ref_end,splice->tbeg,splice->tend,splice->check_utr,splice->check_start,splice->check_stop,splice->check_region_beg,splice->check_region_end); +#endif + + int ret; + if ( splice->ref_beg >= ex_end ) // fully outside, beyond the exon + { + if ( splice->check_utr ) + { + regitr_t *itr = regitr_init(NULL); + const char *chr = bcf_seqname(args->hdr,splice->vcf.rec); + if ( regidx_overlap(args->idx_utr,chr,splice->ref_beg+1,splice->ref_beg+1, itr) ) // adjacent utr + { + ret = csq_stage_utr(args, itr, splice->vcf.rec, splice->tr->id); + if ( ret!=0 ) + { + regitr_destroy(itr); + return SPLICE_OUTSIDE; // overlaps utr + } + } + regitr_destroy(itr); + } + if ( !splice->check_region_end ) return SPLICE_OUTSIDE; + char *ref = NULL, *alt = NULL; + if ( splice->set_refalt ) // seq identity is checked only when tr->ref is available + { + splice_build_hap(splice, ex_end+1, N_SPLICE_REGION_INTRON); + ref = splice->kref.s, alt = splice->kalt.s; + } + if ( splice->ref_beg < ex_end + N_SPLICE_REGION_INTRON && splice->ref_end > ex_end + N_SPLICE_DONOR ) + { + splice->csq |= CSQ_SPLICE_REGION; + if ( ref && !strncmp(ref,alt,N_SPLICE_REGION_INTRON) ) splice->csq |= CSQ_SYNONYMOUS_VARIANT; + } + if ( splice->ref_beg < ex_end + N_SPLICE_DONOR ) + { + if ( splice->check_donor && splice->tr->strand==STRAND_FWD ) splice->csq |= CSQ_SPLICE_DONOR; + if ( splice->check_acceptor && splice->tr->strand==STRAND_REV ) splice->csq |= CSQ_SPLICE_ACCEPTOR; + if ( ref && !strncmp(ref,alt,N_SPLICE_DONOR) ) splice->csq |= CSQ_SYNONYMOUS_VARIANT; + } + csq_stage_splice(args, splice->vcf.rec, splice->tr, splice->csq); + return SPLICE_OUTSIDE; + } + if ( splice->ref_end < ex_beg || (splice->ref_end == ex_beg && !splice->check_region_beg) ) // fully outside, before the exon + { + if ( splice->check_utr ) + { + regitr_t *itr = regitr_init(NULL); + const char *chr = bcf_seqname(args->hdr,splice->vcf.rec); + if ( regidx_overlap(args->idx_utr,chr,splice->ref_end-1,splice->ref_end-1, itr) ) // adjacent utr + { + ret = csq_stage_utr(args, itr, splice->vcf.rec, splice->tr->id); + if ( ret!=0 ) + { + regitr_destroy(itr); + return SPLICE_OUTSIDE; // overlaps utr + } + } + regitr_destroy(itr); + } + if ( !splice->check_region_beg ) return SPLICE_OUTSIDE; + char *ref = NULL, *alt = NULL; + if ( splice->set_refalt ) // seq identity is checked only when tr->ref is available + { + splice_build_hap(splice, ex_beg - N_SPLICE_REGION_INTRON, N_SPLICE_REGION_INTRON); + ref = splice->kref.s, alt = splice->kalt.s; + } + if ( splice->ref_end > ex_beg - N_SPLICE_REGION_INTRON && splice->ref_beg < ex_beg - N_SPLICE_DONOR ) + { + splice->csq |= CSQ_SPLICE_REGION; + if ( ref && !strncmp(ref,alt,N_SPLICE_REGION_INTRON) ) splice->csq |= CSQ_SYNONYMOUS_VARIANT; + } + if ( splice->ref_end > ex_beg - N_SPLICE_DONOR ) + { + if ( splice->check_donor && splice->tr->strand==STRAND_REV ) splice->csq |= CSQ_SPLICE_DONOR; + if ( splice->check_acceptor && splice->tr->strand==STRAND_FWD ) splice->csq |= CSQ_SPLICE_ACCEPTOR; + if ( ref && !strncmp(ref+N_SPLICE_REGION_INTRON-N_SPLICE_DONOR,alt+N_SPLICE_REGION_INTRON-N_SPLICE_DONOR,N_SPLICE_DONOR) ) splice->csq |= CSQ_SYNONYMOUS_VARIANT; + } + csq_stage_splice(args, splice->vcf.rec, splice->tr, splice->csq); + return SPLICE_OUTSIDE; + } + // overlaps the exon or inside the exon + // possible todo: find better alignment for frameshifting variants? + if ( splice->ref_beg <= ex_beg + 2 ) // in the first 3bp + { + if ( splice->check_region_beg ) splice->csq |= CSQ_SPLICE_REGION; + if ( splice->tr->strand==STRAND_FWD ) { if ( splice->check_start ) splice->csq |= CSQ_START_LOST; } + else { if ( splice->check_stop ) splice->csq |= CSQ_STOP_LOST; } + } + if ( splice->ref_end > ex_end - 2 ) + { + if ( splice->check_region_end ) splice->csq |= CSQ_SPLICE_REGION; + if ( splice->tr->strand==STRAND_REV ) { if ( splice->check_start ) splice->csq |= CSQ_START_LOST; } + else { if ( splice->check_stop ) splice->csq |= CSQ_STOP_LOST; } + } + if ( splice->set_refalt ) + { + // Make sure the variant will not end up left aligned to avoid overlapping vcf records + // splice_build_hap(splice, splice->ref_beg, splice->vcf.alen - splice->tend - splice->tbeg + 1); + // splice->vcf.rlen -= splice->tbeg + splice->tend - 1; + // if ( splice->kref.l > splice->vcf.rlen ) { splice->kref.l = splice->vcf.rlen; splice->kref.s[splice->kref.l] = 0; } + if ( splice->ref_beg < splice->vcf.pos ) // this must have been caused by too much trimming from right + { + int dlen = splice->vcf.pos - splice->ref_beg; + assert( dlen==1 ); + splice->tbeg += dlen; + if ( splice->tbeg + splice->tend == splice->vcf.rlen ) splice->tend -= dlen; + splice->ref_beg = splice->vcf.pos; + } + if ( splice->ref_end==ex_beg ) splice->tend--; // prevent zero-length ref allele + splice_build_hap(splice, splice->ref_beg, splice->vcf.alen - splice->tend - splice->tbeg + 1); + splice->vcf.rlen -= splice->tbeg + splice->tend - 1; + if ( splice->kref.l > splice->vcf.rlen ) { splice->kref.l = splice->vcf.rlen; splice->kref.s[splice->kref.l] = 0; } + } + csq_stage_splice(args, splice->vcf.rec, splice->tr, splice->csq); + return SPLICE_INSIDE; +} + +static inline int splice_csq_del(args_t *args, splice_t *splice, uint32_t ex_beg, uint32_t ex_end) +{ + // coordinates that matter for consequences, eg AC>ACG trimmed to C>CG + splice->ref_beg = splice->vcf.pos + splice->tbeg - 1; // 1b before the deleted base + splice->ref_end = splice->vcf.pos + splice->vcf.rlen - splice->tend - 1; // the last deleted base + +#if XDBG +fprintf(stderr,"del: %s>%s .. ex=%d,%d beg,end=%d,%d tbeg,tend=%d,%d check_utr=%d start,stop,beg,end=%d,%d,%d,%d\n", splice->vcf.ref,splice->vcf.alt,ex_beg,ex_end,splice->ref_beg,splice->ref_end,splice->tbeg,splice->tend,splice->check_utr,splice->check_start,splice->check_stop,splice->check_region_beg,splice->check_region_end); +#endif + + if ( splice->ref_beg + 1 < ex_beg ) // the part before the exon; ref_beg is off by -1 + { + if ( splice->check_region_beg ) + { + int csq = 0; + if ( splice->check_utr ) + { + regitr_t *itr = regitr_init(NULL); + const char *chr = bcf_seqname(args->hdr,splice->vcf.rec); + if ( regidx_overlap(args->idx_utr,chr,splice->ref_beg,ex_beg-1, itr) ) // adjacent utr + csq = csq_stage_utr(args, itr, splice->vcf.rec, splice->tr->id); + regitr_destroy(itr); + } + if ( !csq ) + { + char *ref = NULL, *alt = NULL; + if ( splice->set_refalt ) // seq identity is checked only when tr->ref is available + { + // filling from the left does not work for ENST00000341065/frame3.vcf + // CAG.GTGGCCAG CAG.GTGGCCAG + // CA-.--GGCCAG vs CAG.---GCCAG + // splice_build_hap(splice, ex_beg-1, -N_SPLICE_REGION_INTRON); + // + // filling from the right: + splice_build_hap(splice, ex_beg - N_SPLICE_REGION_INTRON, N_SPLICE_REGION_INTRON); + ref = splice->kref.s, alt = splice->kalt.s; + } + if ( splice->ref_end >= ex_beg - N_SPLICE_REGION_INTRON && splice->ref_beg < ex_beg - N_SPLICE_DONOR ) + { + splice->csq |= CSQ_SPLICE_REGION; + if ( ref && alt && !strncmp(ref,alt,N_SPLICE_REGION_INTRON) ) splice->csq |= CSQ_SYNONYMOUS_VARIANT; + } + if ( splice->ref_end >= ex_beg - N_SPLICE_DONOR ) + { + if ( splice->check_donor && splice->tr->strand==STRAND_REV ) splice->csq |= CSQ_SPLICE_DONOR; + if ( splice->check_acceptor && splice->tr->strand==STRAND_FWD ) splice->csq |= CSQ_SPLICE_ACCEPTOR; + if ( ref && alt && !strncmp(ref+N_SPLICE_REGION_INTRON-N_SPLICE_DONOR,alt+N_SPLICE_REGION_INTRON-N_SPLICE_DONOR,N_SPLICE_DONOR) ) splice->csq |= CSQ_SYNONYMOUS_VARIANT; + } + } + } + if ( splice->ref_end >= ex_beg ) + { + splice->tbeg = splice->ref_beg - splice->vcf.pos + 1; + splice->ref_beg = ex_beg - 1; + if ( splice->tbeg + splice->tend == splice->vcf.alen ) + { + // the deletion overlaps ex_beg and cannot be easily realigned to the right + if ( !splice->tend ) + { + splice->csq |= CSQ_CODING_SEQUENCE; + return SPLICE_OVERLAP; + } + splice->tend--; + } + } + } + if ( ex_end < splice->ref_end ) // the part after the exon + { + if ( splice->check_region_end ) + { + int csq = 0; + if ( splice->check_utr ) + { + regitr_t *itr = regitr_init(NULL); + const char *chr = bcf_seqname(args->hdr,splice->vcf.rec); + if ( regidx_overlap(args->idx_utr,chr,ex_end+1,splice->ref_end, itr) ) // adjacent utr + csq = csq_stage_utr(args, itr, splice->vcf.rec, splice->tr->id); + regitr_destroy(itr); + } + if ( !csq ) + { + char *ref = NULL, *alt = NULL; + if ( splice->set_refalt ) // seq identity is checked only when tr->ref is available + { + splice_build_hap(splice, ex_end+1, N_SPLICE_REGION_INTRON); // ref,alt positioned at the first intron base + ref = splice->kref.s, alt = splice->kalt.s; + } + if ( splice->ref_beg < ex_end + N_SPLICE_REGION_INTRON && splice->ref_end > ex_end + N_SPLICE_DONOR ) + { + splice->csq |= CSQ_SPLICE_REGION; + if ( ref && alt && !strncmp(ref,alt,N_SPLICE_REGION_INTRON) ) splice->csq |= CSQ_SYNONYMOUS_VARIANT; + } + if ( splice->ref_beg < ex_end + N_SPLICE_DONOR ) + { + if ( splice->check_donor && splice->tr->strand==STRAND_FWD ) splice->csq |= CSQ_SPLICE_DONOR; + if ( splice->check_acceptor && splice->tr->strand==STRAND_REV ) splice->csq |= CSQ_SPLICE_ACCEPTOR; + if ( ref && alt && !strncmp(ref+N_SPLICE_REGION_INTRON-N_SPLICE_DONOR,alt+N_SPLICE_REGION_INTRON-N_SPLICE_DONOR,N_SPLICE_DONOR) ) splice->csq |= CSQ_SYNONYMOUS_VARIANT; + } + } + } + if ( splice->ref_beg < ex_end ) + { + splice->tend = splice->vcf.rlen - (splice->ref_end - splice->vcf.pos + 1); + splice->ref_end = ex_end; + } + } + if ( splice->ref_end < ex_beg || splice->ref_beg >= ex_end ) + { + csq_stage_splice(args, splice->vcf.rec, splice->tr, splice->csq); + return SPLICE_OUTSIDE; + } + + if ( splice->ref_beg < ex_beg + 2 ) // ref_beg is off by -1 + { + if ( splice->check_region_beg ) splice->csq |= CSQ_SPLICE_REGION; + if ( splice->tr->strand==STRAND_FWD ) { if ( splice->check_start ) splice->csq |= CSQ_START_LOST; } + else { if ( splice->check_stop ) splice->csq |= CSQ_STOP_LOST; } + } + if ( splice->ref_end > ex_end - 3 ) + { + if ( splice->check_region_end ) splice->csq |= CSQ_SPLICE_REGION; + if ( splice->tr->strand==STRAND_REV ) { if ( splice->check_start ) splice->csq |= CSQ_START_LOST; } + else { if ( splice->check_stop ) splice->csq |= CSQ_STOP_LOST; } + } + if ( splice->set_refalt ) + { + if ( splice->tbeg>0 ) splice->tbeg--; //why is this? + if ( splice->vcf.rlen > splice->tbeg + splice->tend && splice->vcf.alen > splice->tbeg + splice->tend ) + { + splice->vcf.rlen -= splice->tbeg + splice->tend; + splice->vcf.alen -= splice->tbeg + splice->tend; + } + splice->kref.l = 0; kputsn(splice->vcf.ref + splice->tbeg, splice->vcf.rlen, &splice->kref); + splice->kalt.l = 0; kputsn(splice->vcf.alt + splice->tbeg, splice->vcf.alen, &splice->kalt); + if ( (splice->ref_beg+1 < ex_beg && splice->ref_end >= ex_beg) || (splice->ref_beg+1 < ex_end && splice->ref_end >= ex_end) ) // ouch, ugly ENST00000409523/long-overlapping-del.vcf + { + splice->csq |= (splice->ref_end - splice->ref_beg + 1)%3 ? CSQ_FRAMESHIFT_VARIANT : CSQ_INFRAME_DELETION; + return SPLICE_OVERLAP; + } + } + csq_stage_splice(args, splice->vcf.rec, splice->tr, splice->csq); + return SPLICE_INSIDE; +} + +static inline int splice_csq_mnp(args_t *args, splice_t *splice, uint32_t ex_beg, uint32_t ex_end) +{ + // not a real variant, can be ignored: eg ACGT>ACGT + if ( splice->tbeg + splice->tend == splice->vcf.rlen ) return SPLICE_VAR_REF; + + splice->ref_beg = splice->vcf.pos + splice->tbeg; + splice->ref_end = splice->vcf.pos + splice->vcf.rlen - splice->tend - 1; + +#if XDBG +fprintf(stderr,"mnp: %s>%s .. ex=%d,%d beg,end=%d,%d tbeg,tend=%d,%d check_utr=%d start,stop,beg,end=%d,%d,%d,%d\n", splice->vcf.ref,splice->vcf.alt,ex_beg,ex_end,splice->ref_beg,splice->ref_end,splice->tbeg,splice->tend,splice->check_utr,splice->check_start,splice->check_stop,splice->check_region_beg,splice->check_region_end); +#endif + + if ( splice->ref_beg < ex_beg ) // the part before the exon + { + if ( splice->check_region_beg ) + { + int csq = 0; + if ( splice->check_utr ) + { + regitr_t *itr = regitr_init(NULL); + const char *chr = bcf_seqname(args->hdr,splice->vcf.rec); + if ( regidx_overlap(args->idx_utr,chr,splice->ref_beg,ex_beg-1, itr) ) // adjacent utr + csq = csq_stage_utr(args, itr, splice->vcf.rec, splice->tr->id); + regitr_destroy(itr); + } + if ( !csq ) + { + if ( splice->ref_end >= ex_beg - N_SPLICE_REGION_INTRON && splice->ref_beg < ex_beg - N_SPLICE_DONOR ) + splice->csq |= CSQ_SPLICE_REGION; + if ( splice->ref_end >= ex_beg - N_SPLICE_DONOR ) + { + if ( splice->check_donor && splice->tr->strand==STRAND_REV ) splice->csq |= CSQ_SPLICE_DONOR; + if ( splice->check_acceptor && splice->tr->strand==STRAND_FWD ) splice->csq |= CSQ_SPLICE_ACCEPTOR; + } + } + } + if ( splice->ref_end >= ex_beg ) + { + splice->tbeg = splice->ref_beg - splice->vcf.pos; + splice->ref_beg = ex_beg; + } + } + if ( ex_end < splice->ref_end ) // the part after the exon + { + if ( splice->check_region_end ) + { + int csq = 0; + if ( splice->check_utr ) + { + regitr_t *itr = regitr_init(NULL); + const char *chr = bcf_seqname(args->hdr,splice->vcf.rec); + if ( regidx_overlap(args->idx_utr,chr,ex_end+1,splice->ref_end, itr) ) // adjacent utr + csq = csq_stage_utr(args, itr, splice->vcf.rec, splice->tr->id); + regitr_destroy(itr); + } + if ( !csq ) + { + if ( splice->ref_beg <= ex_end + N_SPLICE_REGION_INTRON && splice->ref_end > ex_end + N_SPLICE_DONOR ) + splice->csq |= CSQ_SPLICE_REGION; + if ( splice->ref_beg <= ex_end + N_SPLICE_DONOR ) + { + if ( splice->check_donor && splice->tr->strand==STRAND_FWD ) splice->csq |= CSQ_SPLICE_DONOR; + if ( splice->check_acceptor && splice->tr->strand==STRAND_REV ) splice->csq |= CSQ_SPLICE_ACCEPTOR; + } + } + } + if ( splice->ref_beg <= ex_end ) + { + splice->tend = splice->vcf.rlen - (splice->ref_end - splice->vcf.pos + 1); + splice->ref_end = ex_end; + } + } + if ( splice->ref_end < ex_beg || splice->ref_beg > ex_end ) + { + csq_stage_splice(args, splice->vcf.rec, splice->tr, splice->csq); + return SPLICE_OUTSIDE; + } + + if ( splice->ref_beg < ex_beg + 3 ) + { + if ( splice->check_region_beg ) splice->csq |= CSQ_SPLICE_REGION; + if ( splice->tr->strand==STRAND_FWD ) { if ( splice->check_start ) splice->csq |= CSQ_START_LOST; } + else { if ( splice->check_stop ) splice->csq |= CSQ_STOP_LOST; } + } + if ( splice->ref_end > ex_end - 3 ) + { + if ( splice->check_region_end ) splice->csq |= CSQ_SPLICE_REGION; + if ( splice->tr->strand==STRAND_REV ) { if ( splice->check_start ) splice->csq |= CSQ_START_LOST; } + else { if ( splice->check_stop ) splice->csq |= CSQ_STOP_LOST; } + } + if ( splice->set_refalt ) + { + splice->vcf.rlen -= splice->tbeg + splice->tend; + splice->kref.l = 0; kputsn(splice->vcf.ref + splice->tbeg, splice->vcf.rlen, &splice->kref); + splice->kalt.l = 0; kputsn(splice->vcf.alt + splice->tbeg, splice->vcf.rlen, &splice->kalt); + } + csq_stage_splice(args, splice->vcf.rec, splice->tr, splice->csq); + return SPLICE_INSIDE; +} +static inline int splice_csq(args_t *args, splice_t *splice, uint32_t ex_beg, uint32_t ex_end) +{ + splice->csq = 0; + splice->vcf.alen = strlen(splice->vcf.alt); + + int rlen1 = splice->vcf.rlen - 1, alen1 = splice->vcf.alen - 1, i = 0; + splice->tbeg = 0, splice->tend = 0; + + // trim from the right, then from the left + while ( i<=rlen1 && i<=alen1 ) + { + if ( splice->vcf.ref[rlen1-i] != splice->vcf.alt[alen1-i] ) break; + i++; + } + splice->tend = i; + rlen1 -= i, alen1 -= i, i = 0; + while ( i<=rlen1 && i<=alen1 ) + { + if ( splice->vcf.ref[i] != splice->vcf.alt[i] ) break; + i++; + } + splice->tbeg = i; + + // The mnp, ins and del code was split into near-identical functions for clarity and debugging; + // possible todo: generalize once stable + if ( splice->vcf.rlen==splice->vcf.alen ) return splice_csq_mnp(args, splice, ex_beg, ex_end); + if ( splice->vcf.rlen < splice->vcf.alen ) return splice_csq_ins(args, splice, ex_beg, ex_end); + if ( splice->vcf.rlen > splice->vcf.alen ) return splice_csq_del(args, splice, ex_beg, ex_end); + + return 0; +} + +// return value: 0 added, 1 overlapping variant, 2 silent discard (intronic,alt=ref) +int hap_init(args_t *args, hap_node_t *parent, hap_node_t *child, gf_cds_t *cds, bcf1_t *rec, int ial) +{ + int i; + kstring_t str = {0,0,0}; + tscript_t *tr = cds->tr; + child->icds = cds->icds; // index of cds in the tscript's list of exons + + splice_t splice; + splice_init(&splice, rec); + splice.tr = tr; + splice.vcf.alt = rec->d.allele[ial]; + splice.check_acceptor = splice.check_donor = splice.set_refalt = splice.check_utr = 1; + if ( !(tr->trim & TRIM_5PRIME) ) + { + if ( tr->strand==STRAND_FWD ) { if ( child->icds==0 ) splice.check_start = 1; } + else { if ( child->icds==tr->ncds-1 ) splice.check_start = 1; } + } + if ( !(tr->trim & TRIM_3PRIME) ) + { + if ( tr->strand==STRAND_FWD ) { if ( child->icds==tr->ncds-1 ) splice.check_stop = 1; } + else { if ( child->icds==0 ) splice.check_stop = 1; } + } + if ( splice.check_start ) // do not check starts in incomplete CDS, defined as not starting with M + { + if ( tr->strand==STRAND_FWD ) { if ( dna2aa(tr->ref+N_REF_PAD+cds->beg-tr->beg) != 'M' ) splice.check_start = 0; } + else { if ( cdna2aa(tr->ref+N_REF_PAD+cds->beg-tr->beg+cds->len-3) != 'M' ) splice.check_start = 0; } + } + if ( child->icds!=0 ) splice.check_region_beg = 1; + if ( child->icds!=tr->ncds-1 ) splice.check_region_end = 1; + +#if XDBG +fprintf(stderr,"\n%d [%s][%s] check start:%d,stop:%d\n",splice.vcf.pos+1,splice.vcf.ref,splice.vcf.alt,splice.check_start,splice.check_stop); +#endif + int ret = splice_csq(args, &splice, cds->beg, cds->beg + cds->len - 1); +#if XDBG +fprintf(stderr,"cds splice_csq: %d [%s][%s] .. beg,end=%d %d, ret=%d, csq=%d\n\n",splice.vcf.pos+1,splice.kref.s,splice.kalt.s,splice.ref_beg+1,splice.ref_end+1,ret,splice.csq); +#endif + + if ( ret==SPLICE_VAR_REF ) return 2; // not a variant, eg REF=CA ALT=CA + if ( ret==SPLICE_OUTSIDE || ret==SPLICE_OVERLAP ) // not a coding csq + { + free(splice.kref.s); + free(splice.kalt.s); + + if ( !splice.csq ) return 2; // fully intronic, no csq + + // splice_region/acceptor/donor + child->seq = NULL; + child->sbeg = 0; + child->rbeg = rec->pos; + child->rlen = 0; + child->dlen = 0; + kputs(rec->d.allele[0],&str); + kputc('>',&str); + kputs(rec->d.allele[ial],&str); + child->var = str.s; + child->type = HAP_SSS; + child->csq = splice.csq; + child->prev = parent->type==HAP_SSS ? parent->prev : parent; + child->rec = rec; + return 0; + } + if ( splice.csq & CSQ_SYNONYMOUS_VARIANT ) splice.csq &= ~CSQ_SYNONYMOUS_VARIANT; // synonymous&splice,frame could become synonymous&frame,splice + + int dbeg = 0; + if ( splice.ref_beg < cds->beg ) + { + // The vcf record overlaps the exon boundary, but the variant itself + // should fit inside since we are here. This will need more work. + // #1475227917 + dbeg = cds->beg - splice.ref_beg; + splice.kref.l -= dbeg; + splice.ref_beg = cds->beg; + assert( dbeg <= splice.kalt.l ); + } + + if ( parent->type==HAP_SSS ) parent = parent->prev; + if ( parent->type==HAP_CDS ) + { + i = parent->icds; + if ( i!=cds->icds ) + { + // the variant is on a new exon, finish up the previous + int len = tr->cds[i]->len - parent->rbeg - parent->rlen + tr->cds[i]->beg; + if ( len > 0 ) + kputsn_(tr->ref + N_REF_PAD + parent->rbeg + parent->rlen - tr->beg, len, &str); + } + + // append any skipped non-variant exons + while ( ++i < cds->icds ) + kputsn_(tr->ref + N_REF_PAD + tr->cds[i]->beg - tr->beg, tr->cds[i]->len, &str); + + if ( parent->icds==child->icds ) + { + int len = splice.ref_beg - parent->rbeg - parent->rlen; + if ( len < 0 ) // overlapping variants + { + free(str.s); + return 1; + } + kputsn_(tr->ref + N_REF_PAD + parent->rbeg + parent->rlen - tr->beg, len, &str); + } + else + kputsn_(tr->ref + N_REF_PAD + cds->beg - tr->beg, splice.ref_beg - cds->beg, &str); + } + kputs(splice.kalt.s + dbeg, &str); + + child->seq = str.s; + child->sbeg = cds->pos + (splice.ref_beg - cds->beg); + child->rbeg = splice.ref_beg; + child->rlen = splice.kref.l; + child->type = HAP_CDS; + child->prev = parent; + child->rec = rec; + child->csq = splice.csq; + + // set vlen and the "ref>alt" string + { + int rlen = strlen(rec->d.allele[0]); + int alen = strlen(rec->d.allele[ial]); + child->dlen = alen - rlen; + child->var = (char*) malloc(rlen+alen+2); + memcpy(child->var,rec->d.allele[0],rlen); + child->var[rlen] = '>'; + memcpy(child->var+rlen+1,rec->d.allele[ial],alen); + child->var[rlen+alen+1] = 0; + } + + // yuck, the whole CDS is modified/deleted, not ready for this, todo. + if ( child->rbeg + child->rlen > cds->beg + cds->len ) + { + child->type = HAP_SSS; + if ( !child->csq ) child->csq |= CSQ_CODING_SEQUENCE; // hack, specifically for ENST00000390520/deletion-overlap.vcf + } + + free(splice.kref.s); + free(splice.kalt.s); + return 0; +} +void hap_destroy(hap_node_t *hap) +{ + int i; + for (i=0; inchild; i++) + if ( hap->child[i] ) hap_destroy(hap->child[i]); + for (i=0; imcsq_list; i++) free(hap->csq_list[i].type.vstr.s); + free(hap->csq_list); + free(hap->child); + free(hap->cur_child); + free(hap->seq); + free(hap->var); + free(hap); +} + + +/* + ref: spliced reference and its length (ref.l) + seq: part of the spliced query transcript on the reference strand to translate, its + length (seq.l) and the total length of the complete transcript (seq.m) + sbeg: seq offset within the spliced query transcript + rbeg: seq offset within ref, 0-based + rend: last base of seq within ref, plus one. If seq does not contain indels, it is rend=rbeg+seq->l + strand: coding strand - 0:rev, 1:fwd + tseq: translated sequence (aa) + fill: frameshift, fill until the end (strand=fwd) or from the start (strand=rev) + */ +void cds_translate(kstring_t *_ref, kstring_t *_seq, uint32_t sbeg, uint32_t rbeg, uint32_t rend, int strand, kstring_t *tseq, int fill) +{ +#if XDBG +fprintf(stderr,"translate: %d %d %d fill=%d seq.l=%d\n",sbeg,rbeg,rend,fill,(int)_seq->l); +#endif + char tmp[3], *codon, *end; + int i, len, npad; + + kstring_t ref = *_ref; + kstring_t seq = *_seq; + + tseq->l = 0; + if ( !seq.l ) + { + kputc('?', tseq); + return; + } + +#define DBG 0 +#if DBG + fprintf(stderr,"translate: sbeg,rbeg,rend=%d %d %d fill=%d seq.l=%d\n",sbeg,rbeg,rend,fill,(int)_seq->l); + fprintf(stderr," ref: l=%d %s\n", (int)ref.l,ref.s); + fprintf(stderr," seq: l=%d m=%d ", (int)seq.l,(int)seq.m); + for (i=0; i1 + fprintf(stderr," npad: %d\n",npad); +#endif + assert( npad<=rbeg ); + + for (i=0; i1 + fprintf(stderr,"\t i=%d\n", i); +#endif + if ( i==3 ) + { + kputc_(dna2aa(tmp), tseq); +#if DBG>1 + fprintf(stderr,"[1]%c%c%c\n",tmp[0],tmp[1],tmp[2]); +#endif + codon = seq.s + 3 - npad; // next codon + end = codon + len - 1 - (len % 3); // last position of a valid codon + while ( codon < end ) + { + kputc_(dna2aa(codon), tseq); +#if DBG>1 + fprintf(stderr,"[2]%c%c%c\n",codon[0],codon[1],codon[2]); +#endif + codon += 3; + } + end = seq.s + seq.l - 1; + for (i=0; codon+i<=end; i++) tmp[i] = codon[i]; + } + + // right padding + codon = ref.s + rend + N_REF_PAD; + if ( i>0 ) + { +#if DBG>1 + if(i==1)fprintf(stderr,"[3]%c\n",tmp[0]); + if(i==2)fprintf(stderr,"[3]%c%c\n",tmp[0],tmp[1]); +#endif + for (; i<3; i++) + { + tmp[i] = *codon; + codon++; + } + kputc_(dna2aa(tmp), tseq); +#if DBG>1 + fprintf(stderr,"[4]%c%c%c\n",tmp[0],tmp[1],tmp[2]); +#endif + } + if ( fill!=0 ) + { + end = ref.s + ref.l - N_REF_PAD; + while ( codon+3 <= end ) + { + kputc_(dna2aa(codon), tseq); +#if DBG>1 + fprintf(stderr,"[5]%c%c%c\t%c\n",codon[0],codon[1],codon[2],dna2aa(codon)); +#endif + codon += 3; + } + } + } + else // STRAND_REV + { + // right padding - number of bases to take from ref + npad = (seq.m - (sbeg + seq.l)) % 3; +#if DBG>1 + fprintf(stderr," npad: %d\n",npad); +#endif +if ( !(npad>=0 && sbeg+seq.l+npad<=seq.m) ) fprintf(stderr,"sbeg=%d seq.l=%d seq.m=%d\n",sbeg,(int)seq.l,(int)seq.m); + assert( npad>=0 && sbeg+seq.l+npad<=seq.m ); // todo: first codon on the rev strand + + if ( npad==2 ) + { + tmp[1] = ref.s[rend+N_REF_PAD]; + tmp[2] = ref.s[rend+N_REF_PAD+1]; + i = 0; + } + else if ( npad==1 ) + { + tmp[2] = ref.s[rend+N_REF_PAD]; + i = 1; + } + else + i = 2; + + end = seq.s + seq.l; + for (; i>=0 && end>seq.s; i--) tmp[i] = *(--end); +#if DBG>1 + fprintf(stderr,"\t i=%d\n", i); + if(i==1)fprintf(stderr,"[0] %c\n",tmp[2]); + if(i==0)fprintf(stderr,"[0] %c%c\n",tmp[1],tmp[2]); +#endif + if ( i==-1 ) + { +#if DBG>1 + fprintf(stderr,"[1]%c%c%c\t%c\n",tmp[0],tmp[1],tmp[2], cdna2aa(tmp)); +#endif + kputc_(cdna2aa(tmp), tseq); + codon = end - 3; + while ( codon >= seq.s ) + { + kputc_(cdna2aa(codon), tseq); +#if DBG>1 + fprintf(stderr,"[2]%c%c%c\t%c\n",codon[0],codon[1],codon[2], cdna2aa(codon)); +#endif + codon -= 3; + } + if ( seq.s-codon==2 ) + { + tmp[2] = seq.s[0]; + i = 1; + } + else if ( seq.s-codon==1 ) + { + tmp[1] = seq.s[0]; + tmp[2] = seq.s[1]; + i = 0; + } + else + i = -1; +#if DBG>1 + if(i==1)fprintf(stderr,"[3] %c\n",tmp[2]); + if(i==0)fprintf(stderr,"[3] %c%c\n",tmp[1],tmp[2]); +#endif + } + // left padding + end = ref.s + N_REF_PAD + rbeg; + if ( i>=0 ) + { + for (; i>=0 && end>=ref.s; i--) tmp[i] = *(--end); + kputc_(cdna2aa(tmp), tseq); +#if DBG>1 + fprintf(stderr,"[4]%c%c%c\t%c\n",tmp[0],tmp[1],tmp[2],cdna2aa(tmp)); +#endif + } + if ( fill!=0 ) + { + codon = end - 3; + while ( codon >= ref.s + N_REF_PAD ) + { + kputc_(cdna2aa(codon), tseq); +#if DBG>1 + fprintf(stderr,"[5]%c%c%c\t%c\n",codon[0],codon[1],codon[2],cdna2aa(codon)); +#endif + codon -= 3; + } + } + } + kputc_(0,tseq); tseq->l--; +#if DBG + fprintf(stderr," tseq: %s\n", tseq->s); +#endif +} + +void tscript_splice_ref(tscript_t *tr) +{ + int i, len = 0; + for (i=0; incds; i++) + len += tr->cds[i]->len; + + tr->nsref = len + 2*N_REF_PAD; + tr->sref = (char*) malloc(len + 1 + 2*N_REF_PAD); + len = 0; + + memcpy(tr->sref, tr->ref + tr->cds[0]->beg - tr->beg, N_REF_PAD); + len += N_REF_PAD; + + for (i=0; incds; i++) + { + memcpy(tr->sref + len, tr->ref + N_REF_PAD + tr->cds[i]->beg - tr->beg, tr->cds[i]->len); + len += tr->cds[i]->len; + } + memcpy(tr->sref + len, tr->ref + N_REF_PAD + tr->cds[tr->ncds-1]->beg - tr->beg, N_REF_PAD); + len += N_REF_PAD; + + tr->sref[len] = 0; +} + +// returns: 0 if consequence was added, 1 if it already exists or could not be added +int csq_push(args_t *args, csq_t *csq, bcf1_t *rec) +{ +#if XDBG +fprintf(stderr,"csq_push: %d .. %d\n",rec->pos+1,csq->type.type); +#endif + khint_t k = kh_get(pos2vbuf, args->pos2vbuf, (int)csq->pos); + vbuf_t *vbuf = (k == kh_end(args->pos2vbuf)) ? NULL : kh_val(args->pos2vbuf, k); + if ( !vbuf ) error("This should not happen. %s:%d %s\n",bcf_seqname(args->hdr,rec),csq->pos+1,csq->type.vstr); + + int i; + for (i=0; in; i++) + if ( vbuf->vrec[i]->line==rec ) break; + if ( i==vbuf->n ) error("This should not happen.. %s:%d %s\n", bcf_seqname(args->hdr,rec),csq->pos+1,csq->type.vstr); + vrec_t *vrec = vbuf->vrec[i]; + + // if the variant overlaps donor/acceptor and also splice region, report only donor/acceptor + if ( csq->type.type & CSQ_SPLICE_REGION && csq->type.type & (CSQ_SPLICE_DONOR|CSQ_SPLICE_ACCEPTOR) ) + csq->type.type &= ~CSQ_SPLICE_REGION; + + if ( csq->type.type & CSQ_PRINTED_UPSTREAM ) + { + for (i=0; invcsq; i++) + { + // Same as below, to avoid records like + // 3630 .. @3632,stop_lost|AL627309.1|ENST00000423372|protein_coding|- + // 3632 .. stop_lost|AL627309.1|ENST00000423372|protein_coding|-|260*>260G|3630T>A+3632A>C + if ( csq->type.type&CSQ_START_STOP && vrec->vcsq[i].type&CSQ_START_STOP ) + { + vrec->vcsq[i] = csq->type; + goto exit_duplicate; + } + if ( !(vrec->vcsq[i].type & CSQ_PRINTED_UPSTREAM) ) continue; + if ( csq->type.ref != vrec->vcsq[i].ref ) continue; + goto exit_duplicate; + } + } + else if ( csq->type.type & CSQ_COMPOUND ) + { + for (i=0; invcsq; i++) + { + if ( csq->type.trid != vrec->vcsq[i].trid && (csq->type.type|vrec->vcsq[i].type)&CSQ_PRN_TSCRIPT ) continue; + if ( csq->type.biotype != vrec->vcsq[i].biotype ) continue; + if ( csq->type.gene != vrec->vcsq[i].gene ) continue; + if ( csq->type.vstr.s || vrec->vcsq[i].vstr.s ) + { + // This is a bit hacky, but we want a simpler and more predictable output. The splice_csq() function + // can trigger stop/start events based on indel overlap, then another stop/start event can be triggered + // from add_csq() or test_cds_local() based on sequence comparison, and on output we could find two + // consequences: + // stop_lost|AL627309.1|ENST00000423372|protein_coding|- + // stop_lost&inframe_insertion|AL627309.1|ENST00000423372|protein_coding|-|260*>260CL|3630T>TAAA + if ( !csq->type.vstr.s || !vrec->vcsq[i].vstr.s ) + { + if ( csq->type.type&CSQ_START_STOP && vrec->vcsq[i].type&CSQ_START_STOP ) + { + vrec->vcsq[i].type |= csq->type.type; + + // remove stop_lost&synonymous if stop_retained set + if ( vrec->vcsq[i].type&CSQ_STOP_RETAINED ) + vrec->vcsq[i].type &= ~(CSQ_STOP_LOST|CSQ_SYNONYMOUS_VARIANT); + + if ( !vrec->vcsq[i].vstr.s ) vrec->vcsq[i].vstr = csq->type.vstr; + goto exit_duplicate; + } + continue; + } + if ( strcmp(csq->type.vstr.s,vrec->vcsq[i].vstr.s) ) continue; + } + vrec->vcsq[i].type |= csq->type.type; + goto exit_duplicate; + } + } + else + { + for (i=0; invcsq; i++) + { + if ( csq->type.trid != vrec->vcsq[i].trid && (csq->type.type|vrec->vcsq[i].type)&CSQ_PRN_TSCRIPT) continue; + if ( csq->type.biotype != vrec->vcsq[i].biotype ) continue; + if ( !(vrec->vcsq[i].type & CSQ_COMPOUND) ) + { + vrec->vcsq[i].type |= csq->type.type; + goto exit_duplicate; + } + if ( vrec->vcsq[i].type==(vrec->vcsq[i].type|csq->type.type) ) goto exit_duplicate; + } + } + // no such csq yet in this vcf record + csq->vrec = vrec; + csq->idx = i; + vrec->nvcsq++; + hts_expand0(vcsq_t, vrec->nvcsq, vrec->mvcsq, vrec->vcsq); + vrec->vcsq[i] = csq->type; + return 0; + +exit_duplicate: + csq->vrec = vrec; + csq->idx = i; + return 1; +} + +// soff .. position of the variant within the trimmed query transcript +// sbeg .. position of the variant within the query transcript +// rbeg .. position on the reference transcript (if there are no indels, then rbeg=send) +// rpos .. VCF position +#define node2soff(i) (hap->stack[i].slen - (hap->stack[i].node->rlen + hap->stack[i].node->dlen)) +#define node2sbeg(i) (hap->sbeg + node2soff(i)) +#define node2send(i) (hap->sbeg + hap->stack[i].slen) +#define node2rbeg(i) (hap->stack[i].node->sbeg) +#define node2rend(i) (hap->stack[i].node->sbeg + hap->stack[i].node->rlen) +#define node2rpos(i) (hap->stack[i].node->rec->pos) + +void kput_vcsq(vcsq_t *csq, kstring_t *str) +{ + // Remove start/stop from incomplete CDS, but only if there is another + // consequence as something must be reported + if ( csq->type & CSQ_INCOMPLETE_CDS && (csq->type & ~(CSQ_START_STOP|CSQ_INCOMPLETE_CDS|CSQ_UPSTREAM_STOP)) ) csq->type &= ~(CSQ_START_STOP|CSQ_INCOMPLETE_CDS); + + // Remove missense from start/stops + if ( csq->type & CSQ_START_STOP && csq->type & CSQ_MISSENSE_VARIANT ) csq->type &= ~CSQ_MISSENSE_VARIANT; + + if ( csq->type & CSQ_PRINTED_UPSTREAM && csq->ref ) + { + kputc_('@',str); + kputw(csq->ref->pos+1, str); + return; + } + if ( csq->type & CSQ_UPSTREAM_STOP ) + kputc_('*',str); + + int i, n = sizeof(csq_strings)/sizeof(char*); + for (i=1; itype&(1<type&(1<gene ) kputs(csq->gene , str); + + kputc_('|', str); + if ( csq->type & CSQ_PRN_TSCRIPT ) ksprintf(str, "%s",ENSID(csq->trid)); + + kputc_('|', str); + kputs(gf_type2gff_string(csq->biotype), str); + + if ( CSQ_PRN_STRAND(csq->type) || csq->vstr.l ) + kputs(csq->strand==STRAND_FWD ? "|+" : "|-", str); + + if ( csq->vstr.l ) + kputs(csq->vstr.s, str); +} + +void hap_add_csq(args_t *args, hap_t *hap, hap_node_t *node, int tlen, int ibeg, int iend, int dlen, int indel) +{ + int i; + tscript_t *tr = hap->tr; + int ref_node = tr->strand==STRAND_FWD ? ibeg : iend; + + int icsq = node->ncsq_list++; + hts_expand0(csq_t,node->ncsq_list,node->mcsq_list,node->csq_list); + csq_t *csq = &node->csq_list[icsq]; + csq->pos = hap->stack[ref_node].node->rec->pos; + csq->type.trid = tr->id; + csq->type.gene = tr->gene->name; + csq->type.strand = tr->strand; + csq->type.biotype = tr->type; + + // only now we see the translated sequence and can determine if the stop/start changes are real + int rm_csq = 0; + csq->type.type = 0; + for (i=ibeg; i<=iend; i++) + csq->type.type |= hap->stack[i].node->csq & CSQ_COMPOUND; + if ( dlen==0 && indel ) csq->type.type |= CSQ_INFRAME_ALTERING; + + int has_upstream_stop = hap->upstream_stop; + if ( hap->stack[ibeg].node->type != HAP_SSS ) + { + // check for truncating stops + for (i=0; itref.l; i++) + if ( hap->tref.s[i]=='*' ) break; + if ( i!=hap->tref.l ) + { + hap->tref.l = i+1; + hap->tref.s[i+1] = 0; + } + for (i=0; itseq.l; i++) + if ( hap->tseq.s[i]=='*' ) break; + if ( i!=hap->tseq.l ) + { + hap->tseq.l = i+1; + hap->tseq.s[i+1] = 0; + hap->upstream_stop = 1; + } + if ( csq->type.type & CSQ_STOP_LOST ) + { + if ( hap->tref.s[hap->tref.l-1]=='*' && hap->tref.s[hap->tref.l-1] == hap->tseq.s[hap->tseq.l-1] ) + { + rm_csq |= CSQ_STOP_LOST; + csq->type.type |= CSQ_STOP_RETAINED; + } + else if ( hap->tref.s[hap->tref.l-1]!='*' ) + { + // This is CDS 3' incomplete ENSG00000173376/synon.vcf, can also be missense + // We observe in real data a change to a stop, ENST00000528237/retained-stop-incomplete-cds.vcf + if ( hap->tseq.s[hap->tseq.l-1] == '*' ) + { + rm_csq |= CSQ_STOP_GAINED; + csq->type.type |= CSQ_STOP_RETAINED; + } + else + csq->type.type |= CSQ_INCOMPLETE_CDS; + } + } + if ( csq->type.type & CSQ_START_LOST && hap->tref.s[0]!='M' ) + { + rm_csq |= CSQ_START_LOST; + csq->type.type &= ~CSQ_START_LOST; + } + if ( dlen!=0 ) + { + if ( dlen%3 ) + csq->type.type |= CSQ_FRAMESHIFT_VARIANT; + else if ( dlen<0 ) + csq->type.type |= CSQ_INFRAME_DELETION; + else + csq->type.type |= CSQ_INFRAME_INSERTION; + } + else + { + for (i=0; itref.l; i++) + if ( hap->tref.s[i] != hap->tseq.s[i] ) break; + if ( i==hap->tref.l ) + csq->type.type |= CSQ_SYNONYMOUS_VARIANT; + else if ( hap->tref.s[i] == '*' ) + csq->type.type |= CSQ_STOP_LOST; + else if ( hap->tseq.s[i] == '*' ) + csq->type.type |= CSQ_STOP_GAINED; + else + csq->type.type |= CSQ_MISSENSE_VARIANT; + } + } + if ( has_upstream_stop ) csq->type.type |= CSQ_UPSTREAM_STOP; + csq->type.type &= ~rm_csq; + + if ( hap->stack[ibeg].node->type == HAP_SSS ) + { + node->csq_list[icsq].type.type |= hap->stack[ibeg].node->csq & ~rm_csq; + node->csq_list[icsq].type.ref = hap->stack[ibeg].node->rec; + node->csq_list[icsq].type.biotype = tr->type; + csq_push(args, node->csq_list+icsq, hap->stack[ibeg].node->rec); + return; + } + + kstring_t str = node->csq_list[icsq].type.vstr; + str.l = 0; + + // create the aa variant string + int aa_rbeg = tr->strand==STRAND_FWD ? node2rbeg(ibeg)/3+1 : (hap->tr->nsref - 2*N_REF_PAD - node2rend(iend))/3+1; + int aa_sbeg = tr->strand==STRAND_FWD ? node2sbeg(ibeg)/3+1 : (tlen - node2send(iend))/3+1; + kputc_('|', &str); + kputw(aa_rbeg, &str); + kputs(hap->tref.s, &str); + if ( !(csq->type.type & CSQ_SYNONYMOUS_VARIANT) ) + { + kputc_('>', &str); + kputw(aa_sbeg, &str); + kputs(hap->tseq.s, &str); + } + kputc_('|', &str); + + // create the dna variant string and, in case of combined variants, + // insert silent CSQ_PRINTED_UPSTREAM variants + for (i=ibeg; i<=iend; i++) + { + if ( i>ibeg ) kputc_('+', &str); + kputw(node2rpos(i)+1, &str); + kputs(hap->stack[i].node->var, &str); + } + node->csq_list[icsq].type.vstr = str; + csq_push(args, node->csq_list+icsq, hap->stack[ref_node].node->rec); + + for (i=ibeg; i<=iend; i++) + { + // csq are printed at one position only for combined variants, the rest is + // silent and references the first + if ( hap->stack[i].node->csq & ~CSQ_COMPOUND ) + { + node->ncsq_list++; + hts_expand0(csq_t,node->ncsq_list,node->mcsq_list,node->csq_list); + csq_t *tmp_csq = &node->csq_list[node->ncsq_list - 1]; + tmp_csq->pos = hap->stack[i].node->rec->pos; + tmp_csq->type.trid = tr->id; + tmp_csq->type.gene = tr->gene->name; + tmp_csq->type.strand = tr->strand; + tmp_csq->type.type = hap->stack[i].node->csq & ~CSQ_COMPOUND & ~rm_csq; + tmp_csq->type.biotype = tr->type; + tmp_csq->type.vstr.l = 0; + kputs(str.s,&tmp_csq->type.vstr); + csq_push(args, tmp_csq, hap->stack[i].node->rec); + } + if ( i!=ref_node && (node->csq_list[icsq].type.type & CSQ_COMPOUND || !(hap->stack[i].node->csq & ~CSQ_COMPOUND)) ) + { + node->ncsq_list++; + hts_expand0(csq_t,node->ncsq_list,node->mcsq_list,node->csq_list); + csq_t *tmp_csq = &node->csq_list[node->ncsq_list - 1]; + tmp_csq->pos = hap->stack[i].node->rec->pos; + tmp_csq->type.trid = tr->id; + tmp_csq->type.gene = tr->gene->name; + tmp_csq->type.strand = tr->strand; + tmp_csq->type.type = CSQ_PRINTED_UPSTREAM | hap->stack[i].node->csq; + tmp_csq->type.biotype = tr->type; + tmp_csq->type.ref = hap->stack[ref_node].node->rec; + tmp_csq->type.vstr.l = 0; + csq_push(args, tmp_csq, hap->stack[i].node->rec); + } + } +} + +void hap_finalize(args_t *args, hap_t *hap) +{ + tscript_t *tr = hap->tr; + if ( !tr->sref ) + tscript_splice_ref(tr); + + kstring_t sref; + sref.s = tr->sref; + sref.l = tr->nsref; + sref.m = sref.l; + + int istack = 0; + hts_expand(hstack_t,1,hap->mstack,hap->stack); + + hap->sseq.l = 0; + hap->tseq.l = 0; + hap->stack[0].node = tr->root; + hap->stack[0].ichild = -1; + hap->stack[0].slen = 0; + hap->stack[0].dlen = 0; + + while ( istack>=0 ) + { + hstack_t *stack = &hap->stack[istack]; + hap_node_t *node = hap->stack[istack].node; + while ( ++hap->stack[istack].ichild < node->nchild ) + { + if ( node->child[stack->ichild] ) break; + } + if ( stack->ichild == node->nchild ) { istack--; continue; } + + node = node->child[stack->ichild]; + + istack++; + hts_expand(hstack_t,istack+1,hap->mstack,hap->stack); + stack = &hap->stack[istack-1]; + + hap->stack[istack].node = node; + hap->stack[istack].ichild = -1; + + hap->sseq.l = stack->slen; + if ( node->type==HAP_CDS ) kputs(node->seq, &hap->sseq); + hap->stack[istack].slen = hap->sseq.l; + hap->stack[istack].dlen = hap->stack[istack-1].dlen + node->dlen; + + if ( !node->nend ) continue; // not a leaf node + + // The spliced sequence has been built for the current haplotype and stored + // in hap->sseq. Now we break it and output as independent parts + + kstring_t sseq; + sseq.m = sref.m - 2*N_REF_PAD + hap->stack[istack].dlen; // total length of the spliced query transcript + hap->upstream_stop = 0; + + int i = 1, dlen = 0, ibeg, indel = 0; + while ( istack[i].node->type == HAP_SSS ) i++; + hap->sbeg = hap->stack[i].node->sbeg; + + if ( tr->strand==STRAND_FWD ) + { + i = 0, ibeg = -1; + while ( ++i <= istack ) + { + if ( hap->stack[i].node->type == HAP_SSS ) + { + // start/stop/splice site overlap: don't know how to build the haplotypes correctly, skipping + hap_add_csq(args,hap,node,0,i,i,0,0); + continue; + } + dlen += hap->stack[i].node->dlen; + if ( hap->stack[i].node->dlen ) indel = 1; + if ( isseq.l ) + { + sseq.l = hap->stack[i].slen - ioff; + sseq.s = hap->sseq.s + ioff; + } + else // splice site overlap, see #1475227917 + sseq.l = fill = 0; + cds_translate(&sref, &sseq, icur,rbeg,rend, tr->strand, &hap->tseq, fill); + + // ref + sseq.l = node2rend(i) - rbeg; + sseq.s = sref.s + N_REF_PAD + rbeg; + sseq.m = sref.m - 2*N_REF_PAD; + cds_translate(&sref, &sseq, rbeg,rbeg,rend, tr->strand, &hap->tref, fill); + sseq.m = sref.m - 2*N_REF_PAD + hap->stack[istack].dlen; + + hap_add_csq(args,hap,node,0, ibeg,i,dlen,indel); + ibeg = -1; + dlen = 0; + indel = 0; + } + } + else + { + i = istack + 1, ibeg = -1; + while ( --i > 0 ) + { + if ( hap->stack[i].node->type == HAP_SSS ) + { + hap_add_csq(args,hap,node,0,i,i,0,0); + continue; + } + dlen += hap->stack[i].node->dlen; + if ( hap->stack[i].node->dlen ) indel = 1; + if ( i>1 && hap->stack[i-1].node->type != HAP_SSS ) + { + if ( dlen%3 ) + { + if ( ibeg==-1 ) ibeg = i; + continue; + } + int icur = sseq.m - 1 - node2sbeg(i); + int inext = sseq.m - 1 - node2sbeg(i-1); + if ( icur/3 == inext/3 ) + { + if ( ibeg==-1 ) ibeg = i; + continue; + } + } + if ( ibeg<0 ) ibeg = i; + int ioff = node2soff(i); + int icur = node2sbeg(i); + int rbeg = node2rbeg(i); + int rend = node2rend(ibeg); + int fill = dlen%3; + + // alt + if ( hap->sseq.l ) + { + sseq.l = hap->stack[ibeg].slen - ioff; + sseq.s = hap->sseq.s + ioff; + } + else // splice site overlap, see #1475227917 + sseq.l = fill = 0; + cds_translate(&sref, &sseq, icur,rbeg,rend, tr->strand, &hap->tseq, fill); + + // ref + sseq.l = node2rend(ibeg) - rbeg; + sseq.s = sref.s + N_REF_PAD + rbeg; + sseq.m = sref.m - 2*N_REF_PAD; + cds_translate(&sref, &sseq, rbeg,rbeg,rend, tr->strand, &hap->tref, fill); + sseq.m = sref.m - 2*N_REF_PAD + hap->stack[istack].dlen; + + hap_add_csq(args,hap,node,sseq.m, i,ibeg,dlen,indel); + ibeg = -1; + dlen = 0; + indel = 0; + } + } + } +} + +static inline void csq_print_text(args_t *args, csq_t *csq, int ismpl, int ihap) +{ + if ( csq->type.type & CSQ_PRINTED_UPSTREAM ) return; + + char *smpl = ismpl >= 0 ? args->hdr->samples[ismpl] : "-"; + const char *chr = bcf_hdr_id2name(args->hdr,args->rid); + + fprintf(args->out,"CSQ\t%s\t", smpl); + if ( ihap>0 ) + fprintf(args->out,"%d", ihap); + else + fprintf(args->out,"-"); + + args->str.l = 0; + kput_vcsq(&csq->type, &args->str); + fprintf(args->out,"\t%s\t%d\t%s\n",chr,csq->pos+1,args->str.s); +} +static inline void hap_print_text(args_t *args, tscript_t *tr, int ismpl, int ihap, hap_node_t *node) +{ + if ( !node || !node->ncsq_list ) return; + + char *smpl = ismpl >= 0 ? args->hdr->samples[ismpl] : "-"; + const char *chr = bcf_hdr_id2name(args->hdr,args->rid); + + int i; + for (i=0; incsq_list; i++) + { + csq_t *csq = node->csq_list + i; + if ( csq->type.type & CSQ_PRINTED_UPSTREAM ) continue; + assert( csq->type.vstr.l ); + + fprintf(args->out,"CSQ\t%s\t", smpl); + if ( ihap>0 ) + fprintf(args->out,"%d", ihap); + else + fprintf(args->out,"-"); + + args->str.l = 0; + kput_vcsq(&csq->type, &args->str); + fprintf(args->out,"\t%s\t%d\t%s\n",chr,csq->pos+1,args->str.s); + } +} + +static inline void hap_stage_vcf(args_t *args, tscript_t *tr, int ismpl, int ihap, hap_node_t *node) +{ + if ( !node || !node->ncsq_list || ismpl<0 ) return; + + int i; + for (i=0; incsq_list; i++) + { + csq_t *csq = node->csq_list + i; + vrec_t *vrec = csq->vrec; + int icsq = 2*csq->idx + ihap; + if ( icsq >= args->ncsq_max ) // more than ncsq_max consequences, so can't fit it in FMT + { + int print_warning = 1; + if ( args->quiet ) + { + if ( args->quiet > 1 || args->ncsq_small_warned ) print_warning = 0; + args->ncsq_small_warned = 1; + } + if ( print_warning ) + { + fprintf(stderr,"Warning: --ncsq %d is too small to annotate %s at %s:%d with %d-th csq\n", + args->ncsq_max/2,args->hdr->samples[ismpl],bcf_hdr_id2name(args->hdr,args->rid),vrec->line->pos+1,csq->idx+1); + if ( args->quiet ) fprintf(stderr,"(This warning is printed only once)\n"); + } + break; + } + if ( vrec->nfmt < 1 + icsq/32 ) vrec->nfmt = 1 + icsq/32; + vrec->smpl[ismpl*args->nfmt_bcsq + icsq/32] |= 1 << (icsq % 32); + } +} + +void hap_flush(args_t *args, uint32_t pos) +{ + int i,j; + tr_heap_t *heap = args->active_tr; + + while ( heap->ndat && heap->dat[0]->end<=pos ) + { + tscript_t *tr = heap->dat[0]; + khp_delete(trhp, heap); + + args->hap->tr = tr; + if ( tr->root && tr->root->nchild ) // normal, non-localized calling + { + hap_finalize(args, args->hap); + + if ( args->output_type==FT_TAB_TEXT ) // plain text output, not a vcf + { + if ( args->phase==PHASE_DROP_GT ) + hap_print_text(args, tr, -1,0, tr->hap[0]); + else + { + for (i=0; ismpl->n; i++) + { + for (j=0; j<2; j++) + hap_print_text(args, tr, args->smpl->idx[i],j+1, tr->hap[i*2+j]); + } + } + } + else if ( args->phase!=PHASE_DROP_GT ) + { + for (i=0; ismpl->n; i++) + { + for (j=0; j<2; j++) + hap_stage_vcf(args, tr, args->smpl->idx[i],j, tr->hap[i*2+j]); + } + } + } + + // mark the transcript for deletion. Cannot delete it immediately because + // by-position VCF output will need them when flushed by vcf_buf_push + args->nrm_tr++; + hts_expand(tscript_t*,args->nrm_tr,args->mrm_tr,args->rm_tr); + args->rm_tr[args->nrm_tr-1] = tr; + } +} + +#define SWAP(type_t, a, b) { type_t t = a; a = b; b = t; } + +void vbuf_push(args_t *args, bcf1_t **rec_ptr) +{ + int i; + + assert(rec_ptr); + bcf1_t *rec = *rec_ptr; + + // check for duplicate records + i = args->vcf_rbuf.n ? rbuf_last(&args->vcf_rbuf) : -1; + if ( i<0 || args->vcf_buf[i]->vrec[0]->line->pos!=rec->pos ) + { + // vcf record with a new pos + rbuf_expand0(&args->vcf_rbuf, vbuf_t*, args->vcf_rbuf.n+1, args->vcf_buf); + i = rbuf_append(&args->vcf_rbuf); + if ( !args->vcf_buf[i] ) args->vcf_buf[i] = (vbuf_t*) calloc(1,sizeof(vbuf_t)); + args->vcf_buf[i]->n = 0; + } + vbuf_t *vbuf = args->vcf_buf[i]; + vbuf->n++; + hts_expand0(vrec_t*, vbuf->n, vbuf->m, vbuf->vrec); + if ( !vbuf->vrec[vbuf->n - 1] ) + vbuf->vrec[vbuf->n - 1] = (vrec_t*) calloc(1,sizeof(vrec_t)); + + vrec_t *vrec = vbuf->vrec[vbuf->n - 1]; + if ( args->phase!=PHASE_DROP_GT && args->smpl->n ) + { + if ( !vrec->smpl ) vrec->smpl = (uint32_t*) calloc(args->hdr_nsmpl,sizeof(*vrec->smpl) * args->nfmt_bcsq); + else memset(vrec->smpl,0,args->hdr_nsmpl*sizeof(*vrec->smpl) * args->nfmt_bcsq); + } + if ( !vrec->line ) vrec->line = bcf_init1(); + SWAP(bcf1_t*, (*rec_ptr), vrec->line); + + int ret; + khint_t k = kh_put(pos2vbuf, args->pos2vbuf, (int)rec->pos, &ret); + kh_val(args->pos2vbuf,k) = vbuf; +} + +void vbuf_flush(args_t *args) +{ + if ( args->active_tr->ndat ) return; // cannot output buffered VCF lines (args.vbuf) until all active transcripts are gone + + int i,j; + while ( (i=rbuf_shift(&args->vcf_rbuf))>=0 ) + { + vbuf_t *vbuf = args->vcf_buf[i]; + for (i=0; in; i++) + { + vrec_t *vrec = vbuf->vrec[i]; + if ( !args->out_fh ) // not a VCF output + { + vrec->nvcsq = 0; + continue; + } + if ( !vrec->nvcsq ) + { + bcf_write(args->out_fh, args->hdr, vrec->line); + continue; + } + + args->str.l = 0; + kput_vcsq(&vrec->vcsq[0], &args->str); + for (j=1; jnvcsq; j++) + { + kputc_(',', &args->str); + kput_vcsq(&vrec->vcsq[j], &args->str); + } + bcf_update_info_string(args->hdr, vrec->line, args->bcsq_tag, args->str.s); + if ( args->hdr_nsmpl ) + { + if ( vrec->nfmt < args->nfmt_bcsq ) + for (j=1; jhdr_nsmpl; j++) memcpy(vrec->smpl+j*vrec->nfmt, vrec->smpl+j*args->nfmt_bcsq, vrec->nfmt*sizeof(*vrec->smpl)); + bcf_update_format_int32(args->hdr, vrec->line, args->bcsq_tag, vrec->smpl, args->hdr_nsmpl*vrec->nfmt); + } + vrec->nvcsq = 0; + bcf_write(args->out_fh, args->hdr, vrec->line); + } + if ( vbuf->n ) + { + khint_t k = kh_get(pos2vbuf, args->pos2vbuf, vbuf->vrec[0]->line->pos); + if ( k != kh_end(args->pos2vbuf) ) kh_del(pos2vbuf, args->pos2vbuf, k); + } + vbuf->n = 0; + } + + for (i=0; inrm_tr; i++) + { + tscript_t *tr = args->rm_tr[i]; + if ( tr->root ) hap_destroy(tr->root); + tr->root = NULL; + free(tr->hap); + free(tr->ref); + free(tr->sref); + } + args->nrm_tr = 0; + args->ncsq_buf = 0; +} + +void tscript_init_ref(args_t *args, tscript_t *tr, const char *chr) +{ + int i, len; + int pad_beg = tr->beg >= N_REF_PAD ? N_REF_PAD : tr->beg; + + tr->ref = faidx_fetch_seq(args->fai, chr, tr->beg - pad_beg, tr->end + N_REF_PAD, &len); + if ( !tr->ref ) + error("faidx_fetch_seq failed %s:%d-%d\n", chr,tr->beg+1,tr->end+1); + + int pad_end = len - (tr->end - tr->beg + 1 + pad_beg); + if ( pad_beg + pad_end != 2*N_REF_PAD ) + { + char *ref = (char*) malloc(tr->end - tr->beg + 1 + 2*N_REF_PAD); + for (i=0; i < N_REF_PAD - pad_beg; i++) ref[i] = 'N'; + memcpy(ref+i, tr->ref, len); + for (i=0; i < N_REF_PAD - pad_end; i++) ref[i+len] = 'N'; + free(tr->ref); + tr->ref = ref; + } +} + +static void sanity_check_ref(args_t *args, tscript_t *tr, bcf1_t *rec) +{ + char *ref = tr->ref + (rec->pos + N_REF_PAD >= tr->beg ? rec->pos - tr->beg + N_REF_PAD : 0); + char *vcf = rec->d.allele[0] + (rec->pos + N_REF_PAD >= tr->beg ? 0 : tr->beg - N_REF_PAD - rec->pos); + assert( vcf - rec->d.allele[0] < strlen(rec->d.allele[0]) ); + while ( *ref && *vcf ) + { + if ( *ref!=*vcf && toupper(*ref)!=toupper(*vcf) ) + error("Error: the fasta reference does not match the VCF REF allele at %s:%d .. %s\n", bcf_seqname(args->hdr,rec),rec->pos+1,rec->d.allele[0]); + ref++; + vcf++; + } +} + +int test_cds_local(args_t *args, bcf1_t *rec) +{ + int i,j, ret = 0; + const char *chr = bcf_seqname(args->hdr,rec); + // note that the off-by-one extension of rlen is deliberate to account for insertions + if ( !regidx_overlap(args->idx_cds,chr,rec->pos,rec->pos+rec->rlen, args->itr) ) return 0; + + // structures to fake the normal test_cds machinery + hap_node_t root, node; + root.type = HAP_ROOT; + kstring_t *tref = &args->hap->tref, *tseq = &args->hap->tseq; + + while ( regitr_overlap(args->itr) ) + { + gf_cds_t *cds = regitr_payload(args->itr,gf_cds_t*); + tscript_t *tr = cds->tr; + if ( !GF_is_coding(tr->type) ) continue; + ret = 1; + + if ( !tr->ref ) + { + tscript_init_ref(args, tr, chr); + tscript_splice_ref(tr); + khp_insert(trhp, args->active_tr, &tr); // only to clean the reference afterwards + } + + sanity_check_ref(args, tr, rec); + + kstring_t sref; + sref.s = tr->sref; + sref.l = tr->nsref; + sref.m = sref.l; + + for (i=1; in_allele; i++) + { + if ( hap_init(args, &root, &node, cds, rec, i)!=0 ) continue; + + csq_t csq; + memset(&csq, 0, sizeof(csq_t)); + csq.pos = rec->pos; + csq.type.biotype = tr->type; + csq.type.strand = tr->strand; + csq.type.trid = tr->id; + csq.type.gene = tr->gene->name; + + int csq_type = node.csq; + + // code repetition: it would be nice to reuse the code from hap_add_csq, needs have refactoring though + if ( node.type == HAP_SSS ) + { + csq.type.type = csq_type; + csq_stage(args, &csq, rec); + } + else + { + kstring_t sseq; + sseq.m = sref.m - 2*N_REF_PAD + node.dlen; + sseq.s = node.seq; + int alen = sseq.l = strlen(sseq.s); + int fill = node.dlen%3 && alen ? 1 : 0; // see #1475227917 + cds_translate(&sref, &sseq, node.sbeg,node.sbeg,node.sbeg+node.rlen, tr->strand, tseq, fill); + + sseq.m = sref.m - 2*N_REF_PAD; + sseq.s = sref.s + N_REF_PAD + node.sbeg; + sseq.l = node.rlen; + cds_translate(&sref, &sseq, node.sbeg,node.sbeg,node.sbeg+node.rlen, tr->strand, tref, fill); + + // check for truncating stops + for (j=0; jl; j++) + if ( tref->s[j]=='*' ) break; + if ( j!=tref->l ) + { + tref->l = j+1; + tref->s[j+1] = 0; + } + for (j=0; jl; j++) + if ( tseq->s[j]=='*' ) break; + if ( j!=tseq->l ) + { + tseq->l = j+1; + tseq->s[j+1] = 0; + } + if ( csq_type & CSQ_STOP_LOST ) + { + if ( tref->s[tref->l-1]=='*' && tref->s[tref->l-1] == tseq->s[tseq->l-1] ) + { + csq_type &= ~CSQ_STOP_LOST; + csq_type |= CSQ_STOP_RETAINED; + } + else if (tref->s[tref->l-1]!='*' ) + { + // This is CDS 3' incomplete ENSG00000173376/synon.vcf, can also be missense + // We observe in real data a change to a stop, ENST00000528237/retained-stop-incomplete-cds.vcf + if ( tseq->s[tseq->l-1] == '*' ) + { + csq_type &= ~CSQ_STOP_GAINED; + csq_type |= CSQ_STOP_RETAINED; + } + else + csq_type |= CSQ_INCOMPLETE_CDS; + } + } + if ( csq_type & CSQ_START_LOST && tref->s[0]!='M' ) + csq_type &= ~CSQ_START_LOST; + if ( node.dlen!=0 ) + { + if ( node.dlen%3 ) + csq_type |= CSQ_FRAMESHIFT_VARIANT; + else if ( node.dlen<0 ) + csq_type |= CSQ_INFRAME_DELETION; + else + csq_type |= CSQ_INFRAME_INSERTION; + } + else + { + for (j=0; jl; j++) + if ( tref->s[j] != tseq->s[j] ) break; + if ( j==tref->l ) + csq_type |= CSQ_SYNONYMOUS_VARIANT; + else if ( tref->s[j] == '*' ) + csq_type |= CSQ_STOP_LOST; + else if ( tseq->s[j] == '*' ) + csq_type |= CSQ_STOP_GAINED; + else + csq_type |= CSQ_MISSENSE_VARIANT; + } + if ( csq_type & CSQ_COMPOUND ) + { + // create the aa variant string + kstring_t str = {0,0,0}; + int aa_rbeg = tr->strand==STRAND_FWD ? node.sbeg/3+1 : (tr->nsref - 2*N_REF_PAD - node.sbeg - node.rlen)/3+1; + int aa_sbeg = tr->strand==STRAND_FWD ? node.sbeg/3+1 : (tr->nsref - 2*N_REF_PAD + node.dlen - node.sbeg - alen)/3+1; + kputc_('|', &str); + kputw(aa_rbeg, &str); + kputs(tref->s, &str); + if ( !(csq_type & CSQ_SYNONYMOUS_VARIANT) ) + { + kputc_('>', &str); + kputw(aa_sbeg, &str); + kputs(tseq->s, &str); + } + kputc_('|', &str); + kputw(rec->pos+1, &str); + kputs(node.var, &str); + csq.type.vstr = str; + csq.type.type = csq_type & CSQ_COMPOUND; + csq_stage(args, &csq, rec); + + // all this only to clean vstr when vrec is flushed + if ( !tr->root ) + tr->root = (hap_node_t*) calloc(1,sizeof(hap_node_t)); + tr->root->ncsq_list++; + hts_expand0(csq_t,tr->root->ncsq_list,tr->root->mcsq_list,tr->root->csq_list); + csq_t *rm_csq = tr->root->csq_list + tr->root->ncsq_list - 1; + rm_csq->type.vstr = str; + } + if ( csq_type & ~CSQ_COMPOUND ) + { + csq.type.type = csq_type & ~CSQ_COMPOUND; + csq.type.vstr.l = 0; + csq_stage(args, &csq, rec); + } + } + free(node.seq); + free(node.var); + } + } + return ret; +} + +int test_cds(args_t *args, bcf1_t *rec) +{ + int i, ret = 0, hap_ret; + const char *chr = bcf_seqname(args->hdr,rec); + // note that the off-by-one extension of rlen is deliberate to account for insertions + if ( !regidx_overlap(args->idx_cds,chr,rec->pos,rec->pos+rec->rlen, args->itr) ) return 0; + while ( regitr_overlap(args->itr) ) + { + gf_cds_t *cds = regitr_payload(args->itr,gf_cds_t*); + tscript_t *tr = cds->tr; + if ( !GF_is_coding(tr->type) ) continue; + ret = 1; + if ( !tr->root ) + { + // initialize the transcript and its haplotype tree, fetch the reference sequence + tscript_init_ref(args, tr, chr); + + tr->root = (hap_node_t*) calloc(1,sizeof(hap_node_t)); + tr->nhap = args->phase==PHASE_DROP_GT ? 1 : 2*args->smpl->n; // maximum ploidy = diploid + tr->hap = (hap_node_t**) malloc(tr->nhap*sizeof(hap_node_t*)); + for (i=0; inhap; i++) tr->hap[i] = NULL; + tr->root->nend = tr->nhap; + tr->root->type = HAP_ROOT; + + khp_insert(trhp, args->active_tr, &tr); + } + + sanity_check_ref(args, tr, rec); + + if ( args->phase==PHASE_DROP_GT ) + { + if ( rec->d.allele[1][0]=='<' || rec->d.allele[1][0]=='*' ) { continue; } + hap_node_t *parent = tr->hap[0] ? tr->hap[0] : tr->root; + hap_node_t *child = (hap_node_t*)calloc(1,sizeof(hap_node_t)); + if ( (hap_ret=hap_init(args, parent, child, cds, rec, 1))!=0 ) + { + // overlapping or intron variant, cannot apply + if ( hap_ret==1 ) + { + if ( !args->quiet ) + fprintf(stderr,"Warning: Skipping overlapping variants at %s:%d\t%s>%s\n", chr,rec->pos+1,rec->d.allele[0],rec->d.allele[1]); + if ( args->out ) + fprintf(args->out,"LOG\tWarning: Skipping overlapping variants at %s:%d\t%s>%s\n", chr,rec->pos+1,rec->d.allele[0],rec->d.allele[1]); + } + else ret = 1; // prevent reporting as intron in test_tscript + free(child); + continue; + } + parent->nend--; + parent->nchild = 1; + parent->mchild = 1; + parent->child = (hap_node_t**) malloc(sizeof(hap_node_t*)); + parent->child[0] = child; + tr->hap[0] = child; + tr->hap[0]->nend = 1; + continue; + } + + // apply the VCF variants and extend the haplotype tree + int j, ismpl, ihap, ngts = bcf_get_genotypes(args->hdr, rec, &args->gt_arr, &args->mgt_arr); + ngts /= bcf_hdr_nsamples(args->hdr); + if ( ngts!=1 && ngts!=2 ) + { + if ( !args->quiet ) + fprintf(stderr,"Warning: Skipping site with non-diploid/non-haploid genotypes at %s:%d\t%s>%s\n", chr,rec->pos+1,rec->d.allele[0],rec->d.allele[1]); + if ( args->out ) + fprintf(args->out,"LOG\tWarning: Skipping site with non-diploid/non-haploid genotypes at %s:%d\t%s>%s\n", chr,rec->pos+1,rec->d.allele[0],rec->d.allele[1]); + continue; + } + for (ismpl=0; ismplsmpl->n; ismpl++) + { + int32_t *gt = args->gt_arr + args->smpl->idx[ismpl]*ngts; + if ( gt[0]==bcf_gt_missing ) continue; + + if ( ngts>1 && gt[0]!=gt[1] && gt[1]!=bcf_gt_missing && gt[1]!=bcf_int32_vector_end ) + { + if ( args->phase==PHASE_MERGE ) + { + if ( !bcf_gt_allele(gt[0]) ) gt[0] = gt[1]; + } + if ( !bcf_gt_is_phased(gt[0]) && !bcf_gt_is_phased(gt[1]) ) + { + if ( args->phase==PHASE_REQUIRE ) + error("Unphased genotype at %s:%d, sample %s. See the --phase option.\n", chr,rec->pos+1,args->hdr->samples[args->smpl->idx[ismpl]]); + if ( args->phase==PHASE_SKIP ) + continue; + if ( args->phase==PHASE_NON_REF ) + { + if ( !bcf_gt_allele(gt[0]) ) gt[0] = gt[1]; + else if ( !bcf_gt_allele(gt[1]) ) gt[1] = gt[0]; + } + } + } + + for (ihap=0; ihapn_allele ); + if ( rec->d.allele[ial][0]=='<' || rec->d.allele[ial][0]=='*' ) { continue; } + + hap_node_t *parent = tr->hap[i] ? tr->hap[i] : tr->root; + if ( parent->cur_rec==rec && parent->cur_child[ial]>=0 ) + { + // this haplotype has been seen in another sample + tr->hap[i] = parent->child[ parent->cur_child[ial] ]; + tr->hap[i]->nend++; + parent->nend--; + continue; + } + + hap_node_t *child = (hap_node_t*)calloc(1,sizeof(hap_node_t)); + if ( (hap_ret=hap_init(args, parent, child, cds, rec, ial))!=0 ) + { + // overlapping or intron variant, cannot apply + if ( hap_ret==1 ) + { + if ( !args->quiet ) + fprintf(stderr,"Warning: Skipping overlapping variants at %s:%d, sample %s\t%s>%s\n", + chr,rec->pos+1,args->hdr->samples[args->smpl->idx[ismpl]],rec->d.allele[0],rec->d.allele[ial]); + if ( args->out ) + fprintf(args->out,"LOG\tWarning: Skipping overlapping variants at %s:%d, sample %s\t%s>%s\n", + chr,rec->pos+1,args->hdr->samples[args->smpl->idx[ismpl]],rec->d.allele[0],rec->d.allele[ial]); + } + free(child); + continue; + } + + if ( parent->cur_rec!=rec ) + { + hts_expand(int,rec->n_allele,parent->mcur_child,parent->cur_child); + for (j=0; jn_allele; j++) parent->cur_child[j] = -1; + parent->cur_rec = rec; + } + + j = parent->nchild++; + hts_expand0(hap_node_t*,parent->nchild,parent->mchild,parent->child); + parent->cur_child[ial] = j; + parent->child[j] = child; + tr->hap[i] = child; + tr->hap[i]->nend++; + parent->nend--; + } + } + } + return ret; +} + +void csq_stage(args_t *args, csq_t *csq, bcf1_t *rec) +{ + // known issues: tab output leads to unsorted output. This is because + // coding haplotypes are printed in one go and buffering is not used + // with tab output. VCF output is OK though. + if ( csq_push(args, csq, rec)!=0 ) return; // the consequence already exists + + int i,j,ngt = 0; + if ( args->phase!=PHASE_DROP_GT ) + { + ngt = bcf_get_genotypes(args->hdr, rec, &args->gt_arr, &args->mgt_arr); + if ( ngt>0 ) ngt /= bcf_hdr_nsamples(args->hdr); + } + if ( ngt<=0 ) + { + if ( args->output_type==FT_TAB_TEXT ) + csq_print_text(args, csq, -1,0); + return; + } + assert( ngt<=2 ); + + if ( args->output_type==FT_TAB_TEXT ) + { + for (i=0; ismpl->n; i++) + { + int32_t *gt = args->gt_arr + args->smpl->idx[i]*ngt; + for (j=0; jsmpl->idx[i],j+1); + } + } + return; + } + + vrec_t *vrec = csq->vrec; + for (i=0; ismpl->n; i++) + { + int32_t *gt = args->gt_arr + args->smpl->idx[i]*ngt; + for (j=0; jidx + j; + if ( icsq >= args->ncsq_max ) // more than ncsq_max consequences, so can't fit it in FMT + { + int ismpl = args->smpl->idx[i]; + int print_warning = 1; + if ( args->quiet ) + { + if ( args->quiet > 1 || args->ncsq_small_warned ) print_warning = 0; + args->ncsq_small_warned = 1; + } + if ( print_warning ) + { + fprintf(stderr,"Warning: --ncsq %d is too small to annotate %s at %s:%d with %d-th csq\n", + args->ncsq_max/2,args->hdr->samples[ismpl],bcf_hdr_id2name(args->hdr,args->rid),vrec->line->pos+1,csq->idx+1); + if ( args->quiet ) fprintf(stderr,"(This warning is printed only once)\n"); + } + break; + } + if ( vrec->nfmt < 1 + icsq/32 ) vrec->nfmt = 1 + icsq/32; + vrec->smpl[i*args->nfmt_bcsq + icsq/32] |= 1 << (icsq % 32); + } + } +} +int test_utr(args_t *args, bcf1_t *rec) +{ + const char *chr = bcf_seqname(args->hdr,rec); + // note that the off-by-one extension of rlen is deliberate to account for insertions + if ( !regidx_overlap(args->idx_utr,chr,rec->pos,rec->pos+rec->rlen, args->itr) ) return 0; + + splice_t splice; + splice_init(&splice, rec); + + int i, ret = 0; + while ( regitr_overlap(args->itr) ) + { + gf_utr_t *utr = regitr_payload(args->itr, gf_utr_t*); + tscript_t *tr = splice.tr = utr->tr; + for (i=1; in_allele; i++) + { + if ( rec->d.allele[1][0]=='<' || rec->d.allele[1][0]=='*' ) { continue; } + splice.vcf.alt = rec->d.allele[i]; + int splice_ret = splice_csq(args, &splice, utr->beg, utr->end); + if ( splice_ret!=SPLICE_INSIDE && splice_ret!=SPLICE_OVERLAP ) continue; + csq_t csq; + memset(&csq, 0, sizeof(csq_t)); + csq.pos = rec->pos; + csq.type.type = utr->which==prime5 ? CSQ_UTR5 : CSQ_UTR3; + csq.type.biotype = tr->type; + csq.type.strand = tr->strand; + csq.type.trid = tr->id; + csq.type.gene = tr->gene->name; + csq_stage(args, &csq, rec); + ret = 1; + } + } + assert(!splice.kref.s); + assert(!splice.kalt.s); + return ret; +} +int test_splice(args_t *args, bcf1_t *rec) +{ + const char *chr = bcf_seqname(args->hdr,rec); + if ( !regidx_overlap(args->idx_exon,chr,rec->pos,rec->pos + rec->rlen, args->itr) ) return 0; + + splice_t splice; + splice_init(&splice, rec); + splice.check_acceptor = splice.check_donor = 1; + + int i, ret = 0; + while ( regitr_overlap(args->itr) ) + { + gf_exon_t *exon = regitr_payload(args->itr, gf_exon_t*); + splice.tr = exon->tr; + if ( !splice.tr->ncds ) continue; // not a coding transcript, no interest in splice sites + + splice.check_region_beg = splice.tr->beg==exon->beg ? 0 : 1; + splice.check_region_end = splice.tr->end==exon->end ? 0 : 1; + + for (i=1; in_allele; i++) + { + if ( rec->d.allele[1][0]=='<' || rec->d.allele[1][0]=='*' ) { continue; } + splice.vcf.alt = rec->d.allele[i]; + splice_csq(args, &splice, exon->beg, exon->end); + if ( splice.csq ) ret = 1; + } + } + free(splice.kref.s); + free(splice.kalt.s); + return ret; +} +int test_tscript(args_t *args, bcf1_t *rec) +{ + const char *chr = bcf_seqname(args->hdr,rec); + if ( !regidx_overlap(args->idx_tscript,chr,rec->pos,rec->pos+rec->rlen, args->itr) ) return 0; + + splice_t splice; + splice_init(&splice, rec); + + int i, ret = 0; + while ( regitr_overlap(args->itr) ) + { + tscript_t *tr = splice.tr = regitr_payload(args->itr, tscript_t*); + for (i=1; in_allele; i++) + { + if ( rec->d.allele[1][0]=='<' || rec->d.allele[1][0]=='*' ) { continue; } + splice.vcf.alt = rec->d.allele[i]; + int splice_ret = splice_csq(args, &splice, tr->beg, tr->end); + if ( splice_ret!=SPLICE_INSIDE && splice_ret!=SPLICE_OVERLAP ) continue; // SPLICE_OUTSIDE or SPLICE_REF + csq_t csq; + memset(&csq, 0, sizeof(csq_t)); + csq.pos = rec->pos; + csq.type.type = GF_is_coding(tr->type) ? CSQ_INTRON : CSQ_NON_CODING; + csq.type.biotype = tr->type; + csq.type.strand = tr->strand; + csq.type.trid = tr->id; + csq.type.gene = tr->gene->name; + csq_stage(args, &csq, rec); + ret = 1; + } + } + assert(!splice.kref.s); + assert(!splice.kalt.s); + return ret; +} + +void process(args_t *args, bcf1_t **rec_ptr) +{ + if ( !rec_ptr ) + { + hap_flush(args, REGIDX_MAX); + vbuf_flush(args); + return; + } + + bcf1_t *rec = *rec_ptr; + + int call_csq = 1; + if ( !rec->n_allele ) call_csq = 0; // no alternate allele + else if ( rec->n_allele==2 && (rec->d.allele[1][0]=='<' || rec->d.allele[1][0]=='*') ) call_csq = 0; // gVCF, no alt allele + else if ( args->filter ) + { + call_csq = filter_test(args->filter, rec, NULL); + if ( args->filter_logic==FLT_EXCLUDE ) call_csq = call_csq ? 0 : 1; + } + if ( !call_csq ) + { + if ( !args->out_fh ) return; // not a VCF output + vbuf_push(args, rec_ptr); + vbuf_flush(args); + return; + } + + if ( args->rid != rec->rid ) + { + hap_flush(args, REGIDX_MAX); + vbuf_flush(args); + } + args->rid = rec->rid; + vbuf_push(args, rec_ptr); + + int hit = args->local_csq ? test_cds_local(args, rec) : test_cds(args, rec); + hit += test_utr(args, rec); + hit += test_splice(args, rec); + if ( !hit ) test_tscript(args, rec); + + hap_flush(args, rec->pos-1); + vbuf_flush(args); + + return; +} + +const char *usage(void) +{ + return + "\n" + "About: Haplotype-aware consequence caller.\n" + "Usage: bcftools csq [options] in.vcf\n" + "\n" + "Required options:\n" + " -f, --fasta-ref reference file in fasta format\n" + " -g, --gff-annot gff3 annotation file\n" + "\n" + "CSQ options:\n" + " -c, --custom-tag use this tag instead of the default BCSQ\n" + " -l, --local-csq localized predictions, consider only one VCF record at a time\n" + " -n, --ncsq maximum number of consequences to consider per site [16]\n" + " -p, --phase how to construct haplotypes and how to deal with unphased data: [r]\n" + " a: take GTs as is, create haplotypes regardless of phase (0/1 -> 0|1)\n" + " m: merge *all* GTs into a single haplotype (0/1 -> 1, 1/2 -> 1)\n" + " r: require phased GTs, throw an error on unphased het GTs\n" + " R: create non-reference haplotypes if possible (0/1 -> 1|1, 1/2 -> 1|2)\n" + " s: skip unphased GTs\n" + "Options:\n" + " -e, --exclude exclude sites for which the expression is true\n" + " -i, --include select sites for which the expression is true\n" + " -o, --output write output to a file [standard output]\n" + " -O, --output-type b: compressed BCF, u: uncompressed BCF, z: compressed VCF\n" + " v: uncompressed VCF, t: plain tab-delimited text output [v]\n" + " -q, --quiet suppress warning messages. Can be given two times for even less messages\n" + " -r, --regions restrict to comma-separated list of regions\n" + " -R, --regions-file restrict to regions listed in a file\n" + " -s, --samples <-|list> samples to include or \"-\" to apply all variants and ignore samples\n" + " -S, --samples-file samples to include\n" + " -t, --targets similar to -r but streams rather than index-jumps\n" + " -T, --targets-file similar to -R but streams rather than index-jumps\n" + "\n" + "Example:\n" + " bcftools csq -f hs37d5.fa -g Homo_sapiens.GRCh37.82.gff3.gz in.vcf\n" + "\n" + " # GFF3 annotation files can be downloaded from Ensembl. e.g. for human:\n" + " ftp://ftp.ensembl.org/pub/current_gff3/homo_sapiens/\n" + " ftp://ftp.ensembl.org/pub/grch37/release-84/gff3/homo_sapiens/\n" + "\n"; +} + +int main_csq(int argc, char *argv[]) +{ + args_t *args = (args_t*) calloc(1,sizeof(args_t)); + args->argc = argc; args->argv = argv; + args->output_type = FT_VCF; + args->bcsq_tag = "BCSQ"; + args->ncsq_max = 2*16; + + static struct option loptions[] = + { + {"help",0,0,'h'}, + {"ncsq",1,0,'n'}, + {"custom-tag",1,0,'c'}, + {"local-csq",0,0,'l'}, + {"gff-annot",1,0,'g'}, + {"fasta-ref",1,0,'f'}, + {"include",1,0,'i'}, + {"exclude",1,0,'e'}, + {"output",1,0,'o'}, + {"output-type",1,NULL,'O'}, + {"phase",1,0,'p'}, + {"quiet",0,0,'q'}, + {"regions",1,0,'r'}, + {"regions-file",1,0,'R'}, + {"samples",1,0,'s'}, + {"samples-file",1,0,'S'}, + {"targets",1,0,'t'}, + {"targets-file",1,0,'T'}, + {0,0,0,0} + }; + int c, targets_is_file = 0, regions_is_file = 0; + char *targets_list = NULL, *regions_list = NULL; + while ((c = getopt_long(argc, argv, "?hr:R:t:T:i:e:f:o:O:g:s:S:p:qc:ln:",loptions,NULL)) >= 0) + { + switch (c) + { + case 'l': args->local_csq = 1; break; + case 'c': args->bcsq_tag = optarg; break; + case 'q': args->quiet++; break; + case 'p': + switch (optarg[0]) + { + case 'a': args->phase = PHASE_AS_IS; break; + case 'm': args->phase = PHASE_MERGE; break; + case 'r': args->phase = PHASE_REQUIRE; break; + case 'R': args->phase = PHASE_NON_REF; break; + case 's': args->phase = PHASE_SKIP; break; + default: error("The -p code \"%s\" not recognised\n", optarg); + } + break; + case 'f': args->fa_fname = optarg; break; + case 'g': args->gff_fname = optarg; break; + case 'n': + args->ncsq_max = 2 * atoi(optarg); + if ( args->ncsq_max <=0 ) error("Expected positive integer with -n, got %s\n", optarg); + break; + case 'o': args->output_fname = optarg; break; + case 'O': + switch (optarg[0]) { + case 't': args->output_type = FT_TAB_TEXT; break; + case 'b': args->output_type = FT_BCF_GZ; break; + case 'u': args->output_type = FT_BCF; break; + case 'z': args->output_type = FT_VCF_GZ; break; + case 'v': args->output_type = FT_VCF; break; + default: error("The output type \"%s\" not recognised\n", optarg); + } + break; + case 'e': args->filter_str = optarg; args->filter_logic |= FLT_EXCLUDE; break; + case 'i': args->filter_str = optarg; args->filter_logic |= FLT_INCLUDE; break; + case 'r': regions_list = optarg; break; + case 'R': regions_list = optarg; regions_is_file = 1; break; + case 's': args->sample_list = optarg; break; + case 'S': args->sample_list = optarg; args->sample_is_file = 1; break; + case 't': targets_list = optarg; break; + case 'T': targets_list = optarg; targets_is_file = 1; break; + case 'h': + case '?': error("%s",usage()); + default: error("The option not recognised: %s\n\n", optarg); break; + } + } + char *fname = NULL; + if ( optind==argc ) + { + if ( !isatty(fileno((FILE *)stdin)) ) fname = "-"; // reading from stdin + else error("%s", usage()); + } + else fname = argv[optind]; + if ( argc - optind>1 ) error("%s", usage()); + if ( !args->fa_fname ) error("Missing the --fa-ref option\n"); + if ( !args->gff_fname ) error("Missing the --gff option\n"); + args->sr = bcf_sr_init(); + if ( targets_list && bcf_sr_set_targets(args->sr, targets_list, targets_is_file, 0)<0 ) + error("Failed to read the targets: %s\n", targets_list); + if ( regions_list && bcf_sr_set_regions(args->sr, regions_list, regions_is_file)<0 ) + error("Failed to read the regions: %s\n", regions_list); + if ( !bcf_sr_add_reader(args->sr, fname) ) + error("Failed to open %s: %s\n", fname,bcf_sr_strerror(args->sr->errnum)); + args->hdr = bcf_sr_get_header(args->sr,0); + + init_data(args); + while ( bcf_sr_next_line(args->sr) ) + { + process(args, &args->sr->readers[0].buffer[0]); + } + process(args,NULL); + + destroy_data(args); + bcf_sr_destroy(args->sr); + free(args); + + return 0; +} + diff --git a/doc/bcftools.1 b/doc/bcftools.1 new file mode 100644 index 0000000..3999217 --- /dev/null +++ b/doc/bcftools.1 @@ -0,0 +1,4810 @@ +'\" t +.\" Title: bcftools +.\" Author: [see the "AUTHORS" section] +.\" Generator: DocBook XSL Stylesheets v1.76.1 +.\" Date: 2017-05-08 +.\" Manual: \ \& +.\" Source: \ \& +.\" Language: English +.\" +.TH "BCFTOOLS" "1" "2017\-05\-08" "\ \&" "\ \&" +.\" ----------------------------------------------------------------- +.\" * Define some portability stuff +.\" ----------------------------------------------------------------- +.\" ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ +.\" http://bugs.debian.org/507673 +.\" http://lists.gnu.org/archive/html/groff/2009-02/msg00013.html +.\" ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ +.ie \n(.g .ds Aq \(aq +.el .ds Aq ' +.\" ----------------------------------------------------------------- +.\" * set default formatting +.\" ----------------------------------------------------------------- +.\" disable hyphenation +.nh +.\" disable justification (adjust text to left margin only) +.ad l +.\" ----------------------------------------------------------------- +.\" * MAIN CONTENT STARTS HERE * +.\" ----------------------------------------------------------------- +.SH "NAME" +bcftools \- utilities for variant calling and manipulating VCFs and BCFs\&. +.SH "SYNOPSIS" +.sp +\fBbcftools\fR [\-\-version|\-\-version\-only] [\-\-help] [\fICOMMAND\fR] [\fIOPTIONS\fR] +.SH "DESCRIPTION" +.sp +BCFtools is a set of utilities that manipulate variant calls in the Variant Call Format (VCF) and its binary counterpart BCF\&. All commands work transparently with both VCFs and BCFs, both uncompressed and BGZF\-compressed\&. +.sp +Most commands accept VCF, bgzipped VCF and BCF with filetype detected automatically even when streaming from a pipe\&. Indexed VCF and BCF will work in all situations\&. Un\-indexed VCF and BCF and streams will work in most, but not all situations\&. In general, whenever multiple VCFs are read simultaneously, they must be indexed and therefore also compressed\&. +.sp +BCFtools is designed to work on a stream\&. It regards an input file "\-" as the standard input (stdin) and outputs to the standard output (stdout)\&. Several commands can thus be combined with Unix pipes\&. +.SS "VERSION" +.sp +This manual page was last updated \fB2017\-05\-08\fR and refers to bcftools git version \fB1\&.4\&.1\fR\&. +.SS "BCF1" +.sp +The BCF1 format output by versions of samtools <= 0\&.1\&.19 is \fBnot\fR compatible with this version of bcftools\&. To read BCF1 files one can use the view command from old versions of bcftools packaged with samtools versions <= 0\&.1\&.19 to convert to VCF, which can then be read by this version of bcftools\&. +.sp +.if n \{\ +.RS 4 +.\} +.nf + samtools\-0\&.1\&.19/bcftools/bcftools view file\&.bcf1 | bcftools view +.fi +.if n \{\ +.RE +.\} +.SS "VARIANT CALLING" +.sp +See \fIbcftools call\fR for variant calling from the output of the \fIsamtools mpileup\fR command\&. In versions of samtools <= 0\&.1\&.19 calling was done with \fIbcftools view\fR\&. Users are now required to choose between the old samtools calling model (\fI\-c/\-\-consensus\-caller\fR) and the new multiallelic calling model (\fI\-m/\-\-multiallelic\-caller\fR)\&. The multiallelic calling model is recommended for most tasks\&. +.SH "LIST OF COMMANDS" +.sp +For a full list of available commands, run \fBbcftools\fR without arguments\&. For a full list of available options, run \fBbcftools\fR \fICOMMAND\fR without arguments\&. +.sp +.RS 4 +.ie n \{\ +\h'-04'\(bu\h'+03'\c +.\} +.el \{\ +.sp -1 +.IP \(bu 2.3 +.\} + +\fBannotate\fR +\&.\&. edit VCF files, add or remove annotations +.RE +.sp +.RS 4 +.ie n \{\ +\h'-04'\(bu\h'+03'\c +.\} +.el \{\ +.sp -1 +.IP \(bu 2.3 +.\} + +\fBcall\fR +\&.\&. SNP/indel calling (former "view") +.RE +.sp +.RS 4 +.ie n \{\ +\h'-04'\(bu\h'+03'\c +.\} +.el \{\ +.sp -1 +.IP \(bu 2.3 +.\} + +\fBcnv\fR +\&.\&. Copy Number Variation caller +.RE +.sp +.RS 4 +.ie n \{\ +\h'-04'\(bu\h'+03'\c +.\} +.el \{\ +.sp -1 +.IP \(bu 2.3 +.\} + +\fBconcat\fR +\&.\&. concatenate VCF/BCF files from the same set of samples +.RE +.sp +.RS 4 +.ie n \{\ +\h'-04'\(bu\h'+03'\c +.\} +.el \{\ +.sp -1 +.IP \(bu 2.3 +.\} + +\fBconsensus\fR +\&.\&. create consensus sequence by applying VCF variants +.RE +.sp +.RS 4 +.ie n \{\ +\h'-04'\(bu\h'+03'\c +.\} +.el \{\ +.sp -1 +.IP \(bu 2.3 +.\} + +\fBconvert\fR +\&.\&. convert VCF/BCF to other formats and back +.RE +.sp +.RS 4 +.ie n \{\ +\h'-04'\(bu\h'+03'\c +.\} +.el \{\ +.sp -1 +.IP \(bu 2.3 +.\} + +\fBcsq\fR +\&.\&. haplotype aware consequence caller +.RE +.sp +.RS 4 +.ie n \{\ +\h'-04'\(bu\h'+03'\c +.\} +.el \{\ +.sp -1 +.IP \(bu 2.3 +.\} + +\fBfilter\fR +\&.\&. filter VCF/BCF files using fixed thresholds +.RE +.sp +.RS 4 +.ie n \{\ +\h'-04'\(bu\h'+03'\c +.\} +.el \{\ +.sp -1 +.IP \(bu 2.3 +.\} + +\fBgtcheck\fR +\&.\&. check sample concordance, detect sample swaps and contamination +.RE +.sp +.RS 4 +.ie n \{\ +\h'-04'\(bu\h'+03'\c +.\} +.el \{\ +.sp -1 +.IP \(bu 2.3 +.\} + +\fBindex\fR +\&.\&. index VCF/BCF +.RE +.sp +.RS 4 +.ie n \{\ +\h'-04'\(bu\h'+03'\c +.\} +.el \{\ +.sp -1 +.IP \(bu 2.3 +.\} + +\fBisec\fR +\&.\&. intersections of VCF/BCF files +.RE +.sp +.RS 4 +.ie n \{\ +\h'-04'\(bu\h'+03'\c +.\} +.el \{\ +.sp -1 +.IP \(bu 2.3 +.\} + +\fBmerge\fR +\&.\&. merge VCF/BCF files files from non\-overlapping sample sets +.RE +.sp +.RS 4 +.ie n \{\ +\h'-04'\(bu\h'+03'\c +.\} +.el \{\ +.sp -1 +.IP \(bu 2.3 +.\} + +\fBmpileup\fR +\&.\&. multi\-way pileup producing genotype likelihoods +.RE +.sp +.RS 4 +.ie n \{\ +\h'-04'\(bu\h'+03'\c +.\} +.el \{\ +.sp -1 +.IP \(bu 2.3 +.\} + +\fBnorm\fR +\&.\&. normalize indels +.RE +.sp +.RS 4 +.ie n \{\ +\h'-04'\(bu\h'+03'\c +.\} +.el \{\ +.sp -1 +.IP \(bu 2.3 +.\} + +\fBplugin\fR +\&.\&. run user\-defined plugin +.RE +.sp +.RS 4 +.ie n \{\ +\h'-04'\(bu\h'+03'\c +.\} +.el \{\ +.sp -1 +.IP \(bu 2.3 +.\} + +\fBpolysomy\fR +\&.\&. detect contaminations and whole\-chromosome aberrations +.RE +.sp +.RS 4 +.ie n \{\ +\h'-04'\(bu\h'+03'\c +.\} +.el \{\ +.sp -1 +.IP \(bu 2.3 +.\} + +\fBquery\fR +\&.\&. transform VCF/BCF into user\-defined formats +.RE +.sp +.RS 4 +.ie n \{\ +\h'-04'\(bu\h'+03'\c +.\} +.el \{\ +.sp -1 +.IP \(bu 2.3 +.\} + +\fBreheader\fR +\&.\&. modify VCF/BCF header, change sample names +.RE +.sp +.RS 4 +.ie n \{\ +\h'-04'\(bu\h'+03'\c +.\} +.el \{\ +.sp -1 +.IP \(bu 2.3 +.\} + +\fBroh\fR +\&.\&. identify runs of homo/auto\-zygosity +.RE +.sp +.RS 4 +.ie n \{\ +\h'-04'\(bu\h'+03'\c +.\} +.el \{\ +.sp -1 +.IP \(bu 2.3 +.\} + +\fBstats\fR +\&.\&. produce VCF/BCF stats (former vcfcheck) +.RE +.sp +.RS 4 +.ie n \{\ +\h'-04'\(bu\h'+03'\c +.\} +.el \{\ +.sp -1 +.IP \(bu 2.3 +.\} + +\fBview\fR +\&.\&. subset, filter and convert VCF and BCF files +.RE +.SH "LIST OF SCRIPTS" +.sp +Some helper scripts are bundled with the bcftools code\&. +.sp +.RS 4 +.ie n \{\ +\h'-04'\(bu\h'+03'\c +.\} +.el \{\ +.sp -1 +.IP \(bu 2.3 +.\} + +\fBplot\-vcfstats\fR +\&.\&. plots the output of +\fBstats\fR +.RE +.SH "COMMANDS AND OPTIONS" +.SS "Common Options" +.sp +The following options are common to many bcftools commands\&. See usage for specific commands to see if they apply\&. +.PP +\fIFILE\fR +.RS 4 +Files can be both VCF or BCF, uncompressed or BGZF\-compressed\&. The file "\-" is interpreted as standard input\&. Some tools may require tabix\- or CSI\-indexed files\&. +.RE +.PP +\fB\-c, \-\-collapse\fR \fIsnps\fR|\fIindels\fR|\fIboth\fR|\fIall\fR|\fIsome\fR|\fInone\fR|\fIid\fR +.RS 4 +Controls how to treat records with duplicate positions and defines compatible records across multiple input files\&. Here by "compatible" we mean records which should be considered as identical by the tools\&. For example, when performing line intersections, the desire may be to consider as identical all sites with matching positions (\fBbcftools isec \-c\fR +\fIall\fR), or only sites with matching variant type (\fBbcftools isec \-c\fR +\fIsnps\fR\ \& +\fB\-c\fR +\fIindels\fR), or only sites with all alleles identical (\fBbcftools isec \-c\fR +\fInone\fR)\&. +.PP +\fInone\fR +.RS 4 +only records with identical REF and ALT alleles are compatible +.RE +.PP +\fIsome\fR +.RS 4 +only records where some subset of ALT alleles match are compatible +.RE +.PP +\fIall\fR +.RS 4 +all records are compatible, regardless of whether the ALT alleles match or not\&. In the case of records with the same position, only the first will be considered and appear on output\&. +.RE +.PP +\fIsnps\fR +.RS 4 +any SNP records are compatible, regardless of whether the ALT alleles match or not\&. For duplicate positions, only the first SNP record will be considered and appear on output\&. +.RE +.PP +\fIindels\fR +.RS 4 +all indel records are compatible, regardless of whether the REF and ALT alleles match or not\&. For duplicate positions, only the first indel record will be considered and appear on output\&. +.RE +.PP +\fIboth\fR +.RS 4 +abbreviation of "\fB\-c\fR +\fIindels\fR\ \& +\fB\-c\fR +\fIsnps\fR" +.RE +.PP +\fIid\fR +.RS 4 +only records with identical ID column are compatible\&. Supported by +\fBbcftools merge\fR +only\&. +.RE +.RE +.PP +\fB\-f, \-\-apply\-filters\fR \fILIST\fR +.RS 4 +Skip sites where FILTER column does not contain any of the strings listed in +\fILIST\fR\&. For example, to include only sites which have no filters set, use +\fB\-f\fR +\fI\&.,PASS\fR\&. +.RE +.PP +\fB\-\-no\-version\fR +.RS 4 +Do not append version and command line information to the output VCF header\&. +.RE +.PP +\fB\-o, \-\-output\fR \fIFILE\fR +.RS 4 +When output consists of a single stream, write it to +\fIFILE\fR +rather than to standard output, where it is written by default\&. +.RE +.PP +\fB\-O, \-\-output\-type\fR \fIb\fR|\fIu\fR|\fIz\fR|\fIv\fR +.RS 4 +Output compressed BCF (\fIb\fR), uncompressed BCF (\fIu\fR), compressed VCF (\fIz\fR), uncompressed VCF (\fIv\fR)\&. Use the \-Ou option when piping between bcftools subcommands to speed up performance by removing unnecessary compression/decompression and VCF←→BCF conversion\&. +.RE +.PP +\fB\-r, \-\-regions\fR \fIchr\fR|\fIchr:pos\fR|\fIchr:from\-to\fR|\fIchr:from\-\fR[,\&...] +.RS 4 +Comma\-separated list of regions, see also +\fB\-R, \-\-regions\-file\fR\&. Note that +\fB\-r\fR +cannot be used in combination with +\fB\-R\fR\&. +.RE +.PP +\fB\-R, \-\-regions\-file\fR \fIFILE\fR +.RS 4 +Regions can be specified either on command line or in a VCF, BED, or tab\-delimited file (the default)\&. The columns of the tab\-delimited file are: CHROM, POS, and, optionally, POS_TO, where positions are 1\-based and inclusive\&. The columns of the tab\-delimited BED file are also CHROM, POS and POS_TO (trailing columns are ignored), but coordinates are 0\-based, half\-open\&. To indicate that a file be treated as BED rather than the 1\-based tab\-delimited file, the file must have the "\&.bed" or "\&.bed\&.gz" suffix (case\-insensitive)\&. Uncompressed files are stored in memory, while bgzip\-compressed and tabix\-indexed region files are streamed\&. Note that sequence names must match exactly, "chr20" is not the same as "20"\&. Also note that chromosome ordering in +\fIFILE\fR +will be respected, the VCF will be processed in the order in which chromosomes first appear in +\fIFILE\fR\&. However, within chromosomes, the VCF will always be processed in ascending genomic coordinate order no matter what order they appear in +\fIFILE\fR\&. Note that overlapping regions in +\fIFILE\fR +can result in duplicated out of order positions in the output\&. This option requires indexed VCF/BCF files\&. Note that +\fB\-R\fR +cannot be used in combination with +\fB\-r\fR\&. +.RE +.PP +\fB\-s, \-\-samples\fR [^]\fILIST\fR +.RS 4 +Comma\-separated list of samples to include or exclude if prefixed with "^"\&. Note that in general tags such as INFO/AC, INFO/AN, etc are not updated to correspond to the subset samples\&. +\fBbcftools view\fR +is the exception where some tags will be updated (unless the +\fB\-I, \-\-no\-update\fR +option is used; see +\fBbcftools view\fR +documentation)\&. To use updated tags for the subset in another command one can pipe from +\fBview\fR +into that command\&. For example: +.RE +.sp +.if n \{\ +.RS 4 +.\} +.nf + bcftools view \-Ou \-s sample1,sample2 file\&.vcf | bcftools query \-f %INFO/AC\et%INFO/AN\en +.fi +.if n \{\ +.RE +.\} +.PP +\fB\-S, \-\-samples\-file\fR \fIFILE\fR +.RS 4 +File of sample names to include or exclude if prefixed with "^"\&. One sample per line\&. See also the note above for the +\fB\-s, \-\-samples\fR +option\&. The command +\fBbcftools call\fR +accepts an optional second column indicating ploidy (0, 1 or 2) or sex (as defined by +\fB\-\-ploidy\fR, for example "F" or "M"), and can parse also PED files\&. If the second column is not present, the sex "F" is assumed\&. With +\fBbcftools call\fR\fB \-C\fR +\fItrio\fR, PED file is expected\&. File formats examples: +.RE +.sp +.if n \{\ +.RS 4 +.\} +.nf + sample1 1 + sample2 2 + sample3 2 + + or + + sample1 M + sample2 F + sample3 F + + or a \&.ped file (here is shown a minimum working example, the first column is + ignored and the last indicates sex: 1=male, 2=female) + + ignored daughterA fatherA motherA 2 + ignored sonB fatherB motherB 1 +.fi +.if n \{\ +.RE +.\} +.PP +\fB\-t, \-\-targets\fR [^]\fIchr\fR|\fIchr:pos\fR|\fIchr:from\-to\fR|\fIchr:from\-\fR[,\&...] +.RS 4 +Similar as +\fB\-r, \-\-regions\fR, but the next position is accessed by streaming the whole VCF/BCF rather than using the tbi/csi index\&. Both +\fB\-r\fR +and +\fB\-t\fR +options can be applied simultaneously: +\fB\-r\fR +uses the index to jump to a region and +\fB\-t\fR +discards positions which are not in the targets\&. Unlike +\fB\-r\fR, targets can be prefixed with "^" to request logical complement\&. For example, "^X,Y,MT" indicates that sequences X, Y and MT should be skipped\&. Yet another difference between the two is that +\fB\-r\fR +checks both start and end positions of indels, whereas +\fB\-t\fR +checks start positions only\&. Note that +\fB\-t\fR +cannot be used in combination with +\fB\-T\fR\&. +.RE +.PP +\fB\-T, \-\-targets\-file\fR [^]\fIFILE\fR +.RS 4 +Same +\fB\-t, \-\-targets\fR, but reads regions from a file\&. Note that +\fB\-T\fR +cannot be used in combination with +\fB\-t\fR\&. +.RE +.PP +.RS 4 +With the +\fBcall \-C\fR +\fIalleles\fR +command, third column of the targets file must be comma\-separated list of alleles, starting with the reference allele\&. Note that the file must be compressed and index\&. Such a file can be easily created from a VCF using: +.RE +.sp +.if n \{\ +.RS 4 +.\} +.nf + bcftools query \-f\*(Aq%CHROM\et%POS\et%REF,%ALT\en\*(Aq file\&.vcf | bgzip \-c > als\&.tsv\&.gz && tabix \-s1 \-b2 \-e2 als\&.tsv\&.gz +.fi +.if n \{\ +.RE +.\} +.PP +\fB\-\-threads\fR \fIINT\fR +.RS 4 +Number of output compression threads to use in addition to main thread\&. Only used when +\fI\-\-output\-type\fR +is +\fIb\fR +or +\fIz\fR\&. Default: 0\&. +.RE +.SS "bcftools annotate \fI[OPTIONS]\fR \fIFILE\fR" +.sp +Add or remove annotations\&. +.PP +\fB\-a, \-\-annotations\fR \fIfile\fR +.RS 4 +Bgzip\-compressed and tabix\-indexed file with annotations\&. The file can be VCF, BED, or a tab\-delimited file with mandatory columns CHROM, POS (or, alternatively, FROM and TO), optional columns REF and ALT, and arbitrary number of annotation columns\&. BED files are expected to have the "\&.bed" or "\&.bed\&.gz" suffix (case\-insensitive), otherwise a tab\-delimited file is assumed\&. Note that in case of tab\-delimited file, the coordinates POS, FROM and TO are one\-based and inclusive\&. When REF and ALT are present, only matching VCF records will be annotated\&. When multiple ALT alleles are present in the annotation file (given as comma\-separated list of alleles), at least one must match one of the alleles in the corresponding VCF record\&. Similarly, at least one alternate allele from a multi\-allelic VCF record must be present in the annotation file\&. Note that flag types, such as "INFO/FLAG", can be annotated by including a field with the value "1" to set the flag, "0" to remove it, or "\&." to keep existing flags\&. See also +\fB\-c, \-\-columns\fR +and +\fB\-h, \-\-header\-lines\fR\&. +.RE +.sp +.if n \{\ +.RS 4 +.\} +.nf + # Sample annotation file with columns CHROM, POS, STRING_TAG, NUMERIC_TAG + 1 752566 SomeString 5 + 1 798959 SomeOtherString 6 + # etc\&. +.fi +.if n \{\ +.RE +.\} +.PP +\fB\-\-collapse\fR \fIsnps\fR|\fIindels\fR|\fIboth\fR|\fIall\fR|\fIsome\fR|\fInone\fR +.RS 4 +Controls how to match records from the annotation file to the target VCF\&. Effective only when +\fB\-a\fR +is a VCF or BCF\&. See +\fBCommon Options\fR +for more\&. +.RE +.PP +\fB\-c, \-\-columns\fR \fIlist\fR +.RS 4 +Comma\-separated list of columns or tags to carry over from the annotation file (see also +\fB\-a, \-\-annotations\fR)\&. If the annotation file is not a VCF/BCF, +\fIlist\fR +describes the columns of the annotation file and must include CHROM, POS (or, alternatively, FROM and TO), and optionally REF and ALT\&. Unused columns which should be ignored can be indicated by "\-"\&. + +If the annotation file is a VCF/BCF, only the edited columns/tags must be present and their order does not matter\&. The columns ID, QUAL, FILTER, INFO and FORMAT can be edited, where INFO tags can be written both as "INFO/TAG" or simply "TAG", and FORMAT tags can be written as "FORMAT/TAG" or "FMT/TAG"\&. The imported VCF annotations can be renamed as "DST_TAG:=SRC_TAG" or "FMT/DST_TAG:=FMT/SRC_TAG"\&. + +To carry over all INFO annotations, use "INFO"\&. To add all INFO annotations except "TAG", use "^INFO/TAG"\&. By default, existing values are replaced\&. + +To add annotations without overwriting existing values (that is, to add missing tags or add values to existing tags with missing values), use "+TAG" instead of "TAG"\&. To append to existing values (rather than replacing or leaving untouched), use "=TAG" (instead of "TAG" or "+TAG")\&. To replace only existing values without modifying missing annotations, use "\-TAG"\&. + +If the annotation file is not a VCF/BCF, all new annotations must be defined via +\fB\-h, \-\-header\-lines\fR\&. +.RE +.PP +\fB\-e, \-\-exclude\fR \fIEXPRESSION\fR +.RS 4 +exclude sites for which +\fIEXPRESSION\fR +is true\&. For valid expressions see +\fBEXPRESSIONS\fR\&. +.RE +.PP +\fB\-h, \-\-header\-lines\fR \fIfile\fR +.RS 4 +Lines to append to the VCF header, see also +\fB\-c, \-\-columns\fR +and +\fB\-a, \-\-annotations\fR\&. For example: +.RE +.sp +.if n \{\ +.RS 4 +.\} +.nf + ##INFO= + ##INFO= +.fi +.if n \{\ +.RE +.\} +.PP +\fB\-I, \-\-set\-id\fR [+]\fIFORMAT\fR +.RS 4 +assign ID on the fly\&. The format is the same as in the +\fBquery\fR +command (see below)\&. By default all existing IDs are replaced\&. If the format string is preceded by "+", only missing IDs will be set\&. For example, one can use +.RE +.sp +.if n \{\ +.RS 4 +.\} +.nf + bcftools annotate \-\-set\-id +\*(Aq%CHROM\e_%POS\e_%REF\e_%FIRST_ALT\*(Aq file\&.vcf +.fi +.if n \{\ +.RE +.\} +.PP +\fB\-i, \-\-include\fR \fIEXPRESSION\fR +.RS 4 +include only sites for which +\fIEXPRESSION\fR +is true\&. For valid expressions see +\fBEXPRESSIONS\fR\&. +.RE +.PP +\fB\-m, \-\-mark\-sites\fR \fITAG\fR +.RS 4 +annotate sites which are present ("+") or absent ("\-") in the +\fB\-a\fR +file with a new INFO/TAG flag +.RE +.PP +\fB\-\-no\-version\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-o, \-\-output\fR \fIFILE\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-O, \-\-output\-type\fR \fIb\fR|\fIu\fR|\fIz\fR|\fIv\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-r, \-\-regions\fR \fIchr\fR|\fIchr:pos\fR|\fIchr:from\-to\fR|\fIchr:from\-\fR[,\&...] +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-R, \-\-regions\-file\fR \fIfile\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-\-rename\-chrs\fR \fIfile\fR +.RS 4 +rename chromosomes according to the map in +\fIfile\fR, with "old_name new_name\en" pairs separated by whitespaces, each on a separate line\&. +.RE +.PP +\fB\-s, \-\-samples\fR [^]\fILIST\fR +.RS 4 +subset of samples to annotate, see also +\fBCommon Options\fR +.RE +.PP +\fB\-S, \-\-samples\-file\fR \fIFILE\fR +.RS 4 +subset of samples to annotate\&. If the samples are named differently in the target VCF and the +\fB\-a, \-\-annotations\fR +VCF, the name mapping can be given as "src_name dst_name\en", separated by whitespaces, each pair on a separate line\&. +.RE +.PP +\fB\-\-threads\fR \fIINT\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-x, \-\-remove\fR \fIlist\fR +.RS 4 +List of annotations to remove\&. Use "FILTER" to remove all filters or "FILTER/SomeFilter" to remove a specific filter\&. Similarly, "INFO" can be used to remove all INFO tags and "FORMAT" to remove all FORMAT tags except GT\&. To remove all INFO tags except "FOO" and "BAR", use "^INFO/FOO,INFO/BAR" (and similarly for FORMAT and FILTER)\&. "INFO" can be abbreviated to "INF" and "FORMAT" to "FMT"\&. +.RE +.sp +\fBExamples:\fR +.sp +.if n \{\ +.RS 4 +.\} +.nf + # Remove three fields + bcftools annotate \-x ID,INFO/DP,FORMAT/DP file\&.vcf\&.gz + + # Remove all INFO fields and all FORMAT fields except for GT and PL + bcftools annotate \-x INFO,^FORMAT/GT,FORMAT/PL file\&.vcf + + # Add ID, QUAL and INFO/TAG, not replacing TAG if already present + bcftools annotate \-a src\&.bcf \-c ID,QUAL,+TAG dst\&.bcf + + # Carry over all INFO and FORMAT annotations except FORMAT/GT + bcftools annotate \-a src\&.bcf \-c INFO,^FORMAT/GT dst\&.bcf + + # Annotate from a tab\-delimited file with six columns (the fifth is ignored), + # first indexing with tabix\&. The coordinates are 1\-based\&. + tabix \-s1 \-b2 \-e2 annots\&.tab\&.gz + bcftools annotate \-a annots\&.tab\&.gz \-h annots\&.hdr \-c CHROM,POS,REF,ALT,\-,TAG file\&.vcf + + # Annotate from a tab\-delimited file with regions (1\-based coordinates, inclusive) + tabix \-s1 \-b2 \-e3 annots\&.tab\&.gz + bcftools annotate \-a annots\&.tab\&.gz \-h annots\&.hdr \-c CHROM,FROM,TO,TAG inut\&.vcf + + # Annotate from a bed file (0\-based coordinates, half\-closed, half\-open intervals) + bcftools annotate \-a annots\&.bed\&.gz \-h annots\&.hdr \-c CHROM,FROM,TO,TAG input\&.vcf +.fi +.if n \{\ +.RE +.\} +.SS "bcftools call \fI[OPTIONS]\fR \fIFILE\fR" +.sp +This command replaces the former \fBbcftools view\fR caller\&. Some of the original functionality has been temporarily lost in the process of transition under htslib, but will be added back on popular demand\&. The original calling model can be invoked with the \fB\-c\fR option\&. +.sp +.it 1 an-trap +.nr an-no-space-flag 1 +.nr an-break-flag 1 +.br +.ps +1 +\fBFile format options:\fR +.RS 4 +.PP +\fB\-\-no\-version\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-o, \-\-output\fR \fIFILE\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-O, \-\-output\-type\fR \fIb\fR|\fIu\fR|\fIz\fR|\fIv\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-\-ploidy\fR \fIASSEMBLY\fR[\fI?\fR] +.RS 4 +predefined ploidy, use +\fIlist\fR +(or any other unused word) to print a list of all predefined assemblies\&. Append a question mark to print the actual definition\&. See also +\fB\-\-ploidy\-file\fR\&. +.RE +.PP +\fB\-\-ploidy\-file\fR \fIFILE\fR +.RS 4 +ploidy definition given as a space/tab\-delimited list of CHROM, FROM, TO, SEX, PLOIDY\&. The SEX codes are arbitrary and correspond to the ones used by +\fB\-\-samples\-file\fR\&. The default ploidy can be given using the starred records (see below), unlisted regions have ploidy 2\&. The default ploidy definition is +.RE +.sp +.if n \{\ +.RS 4 +.\} +.nf + X 1 60000 M 1 + X 2699521 154931043 M 1 + Y 1 59373566 M 1 + Y 1 59373566 F 0 + MT 1 16569 M 1 + MT 1 16569 F 1 + * * * M 2 + * * * F 2 +.fi +.if n \{\ +.RE +.\} +.PP +\fB\-r, \-\-regions\fR \fIchr\fR|\fIchr:pos\fR|\fIchr:from\-to\fR|\fIchr:from\-\fR[,\&...] +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-R, \-\-regions\-file\fR \fIfile\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-s, \-\-samples\fR \fILIST\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-S, \-\-samples\-file\fR \fIFILE\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-t, \-\-targets\fR \fILIST\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-T, \-\-targets\-file\fR \fIFILE\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-\-threads\fR \fIINT\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.RE +.sp +.it 1 an-trap +.nr an-no-space-flag 1 +.nr an-break-flag 1 +.br +.ps +1 +\fBInput/output options:\fR +.RS 4 +.PP +\fB\-A, \-\-keep\-alts\fR +.RS 4 +output all alternate alleles present in the alignments even if they do not appear in any of the genotypes +.RE +.PP +\fB\-f, \-\-format\-fields\fR \fIlist\fR +.RS 4 +comma\-separated list of FORMAT fields to output for each sample\&. Currently GQ and GP fields are supported\&. For convenience, the fields can be given as lower case letters\&. +.RE +.PP +\fB\-F, \-\-prior\-freqs\fR \fIAN\fR,\fIAC\fR +.RS 4 +take advantage of prior knowledge of population allele frequencies\&. The workflow looks like this: +.RE +.sp +.if n \{\ +.RS 4 +.\} +.nf + # Extract AN,AC values from an existing VCF, such 1000Genomes + bcftools query \-f\*(Aq%CHROM\et%POS\et%REF\et%ALT\et%AN\et%AC\en\*(Aq 1000Genomes\&.bcf | bgzip \-c > AFs\&.tab\&.gz + + # If the tags AN,AC are not already present, use the +fill\-AN\-AC plugin + bcftools +fill\-AN\-AC 1000Genomes\&.bcf | bcftools query \-f\*(Aq%CHROM\et%POS\et%REF\et%ALT\et%AN\et%AC\en\*(Aq | bgzip \-c > AFs\&.tab\&.gz + tabix \-s1 \-b2 \-e2 AFs\&.tab\&.gz + + # Create a VCF header description, here we name the tags REF_AN,REF_AC + cat AFs\&.hdr + ##INFO= + ##INFO= + + # Now before calling, stream the raw mpileup output through `bcftools annotate` to add the frequencies + bcftools mpileup [\&.\&.\&.] \-Ou | bcftools annotate \-a AFs\&.tab\&.gz \-h AFs\&.hdr \-c CHROM,POS,REF,ALT,REF_AN,REF_AC \-Ou | bcftools call \-mv \-F REF_AN,REF_AC [\&.\&.\&.] +.fi +.if n \{\ +.RE +.\} +.PP +\fB\-g, \-\-gvcf\fR \fIINT\fR +.RS 4 +output also gVCF blocks of homozygous REF calls\&. The parameter +\fIINT\fR +is the minimum per\-sample depth required to include a site in the non\-variant block\&. +.RE +.PP +\fB\-i, \-\-insert\-missed\fR \fIINT\fR +.RS 4 +output also sites missed by mpileup but present in +\fB\-T, \-\-targets\-file\fR\&. +.RE +.PP +\fB\-M, \-\-keep\-masked\-ref\fR +.RS 4 +output sites where REF allele is N +.RE +.PP +\fB\-V, \-\-skip\-variants\fR \fIsnps\fR|\fIindels\fR +.RS 4 +skip indel/SNP sites +.RE +.PP +\fB\-v, \-\-variants\-only\fR +.RS 4 +output variant sites only +.RE +.RE +.sp +.it 1 an-trap +.nr an-no-space-flag 1 +.nr an-break-flag 1 +.br +.ps +1 +\fBConsensus/variant calling options:\fR +.RS 4 +.PP +\fB\-c, \-\-consensus\-caller\fR +.RS 4 +the original +\fBsamtools\fR/\fBbcftools\fR +calling method (conflicts with +\fB\-m\fR) +.RE +.PP +\fB\-C, \-\-constrain\fR \fIalleles\fR|\fItrio\fR +.RS 4 +.PP +\fIalleles\fR +.RS 4 +call genotypes given alleles\&. See also +\fB\-T, \-\-targets\-file\fR\&. +.RE +.PP +\fItrio\fR +.RS 4 +call genotypes given the father\-mother\-child constraint\&. See also +\fB\-s, \-\-samples\fR +and +\fB\-n, \-\-novel\-rate\fR\&. +.RE +.RE +.PP +\fB\-m, \-\-multiallelic\-caller\fR +.RS 4 +alternative modelfor multiallelic and rare\-variant calling designed to overcome known limitations in +\fB\-c\fR +calling model (conflicts with +\fB\-c\fR) +.RE +.PP +\fB\-n, \-\-novel\-rate\fR \fIfloat\fR[,\&...] +.RS 4 +likelihood of novel mutation for constrained +\fB\-C\fR +\fItrio\fR +calling\&. The trio genotype calling maximizes likelihood of a particular combination of genotypes for father, mother and the child P(F=i,M=j,C=k) = P(unconstrained) * Pn + P(constrained) * (1\-Pn)\&. By providing three values, the mutation rate Pn is set explicitly for SNPs, deletions and insertions, respectively\&. If two values are given, the first is interpreted as the mutation rate of SNPs and the second is used to calculate the mutation rate of indels according to their length as Pn=\fIfloat\fR*exp(\-a\-b*len), where a=22\&.8689, b=0\&.2994 for insertions and a=21\&.9313, b=0\&.2856 for deletions [pubmed:23975140]\&. If only one value is given, the same mutation rate Pn is used for SNPs and indels\&. +.RE +.PP +\fB\-p, \-\-pval\-threshold\fR \fIfloat\fR +.RS 4 +with +\fB\-c\fR, accept variant if P(ref|D) < +\fIfloat\fR\&. +.RE +.PP +\fB\-P, \-\-prior\fR \fIfloat\fR +.RS 4 +expected substitution rate, or 0 to disable the prior\&. Only with +\fB\-m\fR\&. +.RE +.PP +\fB\-t, \-\-targets\fR \fIfile\fR|\fIchr\fR|\fIchr:pos\fR|\fIchr:from\-to\fR|\fIchr:from\-\fR[,\&...] +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-X, \-\-chromosome\-X\fR +.RS 4 +haploid output for male samples (requires PED file with +\fB\-s\fR) +.RE +.PP +\fB\-Y, \-\-chromosome\-Y\fR +.RS 4 +haploid output for males and skips females (requires PED file with +\fB\-s\fR) +.RE +.RE +.SS "bcftools cnv \fI[OPTIONS]\fR \fIFILE\fR" +.sp +Copy number variation caller, requires a VCF annotated with the Illumina\(cqs B\-allele frequency (BAF) and Log R Ratio intensity (LRR) values\&. The HMM considers the following copy number states: CN 2 (normal), 1 (single\-copy loss), 0 (complete loss), 3 (single\-copy gain)\&. +.sp +.it 1 an-trap +.nr an-no-space-flag 1 +.nr an-break-flag 1 +.br +.ps +1 +\fBGeneral Options:\fR +.RS 4 +.PP +\fB\-c, \-\-control\-sample\fR \fIstring\fR +.RS 4 +optional control sample name\&. If given, pairwise calling is performed and the +\fB\-P\fR +option can be used +.RE +.PP +\fB\-f, \-\-AF\-file\fR \fIfile\fR +.RS 4 +read allele frequencies from a tab\-delimited file with the columns CHR,POS,REF,ALT,AF +.RE +.PP +*\-o, \-\-output\-dir \fIpath\fR +.RS 4 +output directory +.RE +.PP +*\-p, \-\-plot\-threshold \fIfloat\fR +.RS 4 +call +\fBmatplotlib\fR +to produce plots for chromosomes with quality at least +\fIfloat\fR, useful for visual inspection of the calls\&. With +\fB\-p 0\fR, plots for all chromosomes will be generated\&. If not given, a +\fBmatplotlib\fR +script will be created but not called\&. +.RE +.PP +\fB\-r, \-\-regions\fR \fIchr\fR|\fIchr:pos\fR|\fIchr:from\-to\fR|\fIchr:from\-\fR[,\&...] +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-R, \-\-regions\-file\fR \fIfile\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-s, \-\-query\-sample\fR \fIstring\fR +.RS 4 +query samply name +.RE +.PP +\fB\-t, \-\-targets\fR \fILIST\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-T, \-\-targets\-file\fR \fIFILE\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.RE +.sp +.it 1 an-trap +.nr an-no-space-flag 1 +.nr an-break-flag 1 +.br +.ps +1 +\fBHMM Options:\fR +.RS 4 +.PP +\fB\-a, \-\-aberrant\fR \fIfloat\fR[,\fIfloat\fR] +.RS 4 +fraction of aberrant cells in query and control\&. The hallmark of duplications and contaminations is the BAF value of heterozygous markers which is dependent on the fraction of aberrant cells\&. Sensitivity to smaller fractions of cells can be increased by setting +\fB\-a\fR +to a lower value\&. Note however, that this comes at the cost of increased false discovery rate\&. +.RE +.PP +\fB\-b, \-\-BAF\-weight\fR \fIfloat\fR +.RS 4 +relative contribution from BAF +.RE +.PP +\fBd, \-\-BAF\-dev\fR \fIfloat\fR[,\fIfloat\fR] +.RS 4 +expected BAF deviation in query and control, i\&.e\&. the noise observed in the data\&. +.RE +.PP +\fB\-e, \-\-err\-prob\fR \fIfloat\fR +.RS 4 +uniform error probability +.RE +.PP +\fB\-l, \-\-LRR\-weight\fR \fIfloat\fR +.RS 4 +relative contribution from LRR\&. With noisy data, this option can have big effect on the number of calls produced\&. In truly random noise (such as in simulated data), the value should be set high (1\&.0), but in the presence of systematic noise when LRR are not informative, lower values result in cleaner calls (0\&.2)\&. +.RE +.PP +\fB\-L, \-\-LRR\-smooth\-win\fR \fIint\fR +.RS 4 +reduce LRR noise by applying moving average given this window size +.RE +.PP +\fB\-O, \-\-optimize\fR \fIfloat\fR +.RS 4 +iteratively estimate the fraction of aberrant cells, down to the given fraction\&. Lowering this value from the default 1\&.0 to say, 0\&.3, can help discover more events but also increases noise +.RE +.PP +\fB\-P, \-\-same\-prob\fR \fIfloat\fR +.RS 4 +the prior probability of the query and the control sample being the same\&. Setting to 0 calls both independently, setting to 1 forces the same copy number state in both\&. +.RE +.PP +\fB\-x, \-\-xy\-prob\fR \fIfloat\fR +.RS 4 +the HMM probability of transition to another copy number state\&. Increasing this values leads to smaller and more frequent calls\&. +.RE +.RE +.SS "bcftools concat \fI[OPTIONS]\fR \fIFILE1\fR \fIFILE2\fR [\&...]" +.sp +Concatenate or combine VCF/BCF files\&. All source files must have the same sample columns appearing in the same order\&. Can be used, for example, to concatenate chromosome VCFs into one VCF, or combine a SNP VCF and an indel VCF into one\&. The input files must be sorted by chr and position\&. The files must be given in the correct order to produce sorted VCF on output unless the \fB\-a, \-\-allow\-overlaps\fR option is specified\&. With the \-\-naive option, the files are concatenated without being recompressed, which is very fast but dangerous if the BCF headers differ\&. +.PP +\fB\-a, \-\-allow\-overlaps\fR +.RS 4 +First coordinate of the next file can precede last record of the current file\&. +.RE +.PP +\fB\-c, \-\-compact\-PS\fR +.RS 4 +Do not output PS tag at each site, only at the start of a new phase set block\&. +.RE +.PP +\fB\-d, \-\-rm\-dups\fR \fIsnps\fR|\fIindels\fR|\fIboth\fR|\fIall\fR|\fInone\fR +.RS 4 +Output duplicate records of specified type present in multiple files only once\&. Requires +\fB\-a, \-\-allow\-overlaps\fR\&. +.RE +.PP +\fB\-D, \-\-remove\-duplicates\fR +.RS 4 +Alias for +\fB\-d none\fR +.RE +.PP +\fB\-f, \-\-file\-list\fR \fIFILE\fR +.RS 4 +Read file names from +\fIFILE\fR, one file name per line\&. +.RE +.PP +\fB\-l, \-\-ligate\fR +.RS 4 +Ligate phased VCFs by matching phase at overlapping haplotypes +.RE +.PP +\fB\-\-no\-version\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-n, \-\-naive\fR +.RS 4 +Concatenate VCF or BCF files without recompression\&. This is very fast but requires that all files are of the same type (all VCF or all BCF) and have the same headers\&. This is because all tags and chromosome names in the BCF body rely on the implicit order of the contig and tag definitions in the header\&. Currently no sanity checks are in place\&. Dangerous, use with caution\&. +.RE +.PP +\fB\-o, \-\-output\fR \fIFILE\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-O, \-\-output\-type\fR \fIb\fR|\fIu\fR|\fIz\fR|\fIv\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-q, \-\-min\-PQ\fR \fIINT\fR +.RS 4 +Break phase set if phasing quality is lower than +\fIINT\fR +.RE +.PP +\fB\-r, \-\-regions\fR \fIchr\fR|\fIchr:pos\fR|\fIchr:from\-to\fR|\fIchr:from\-\fR[,\&...] +.RS 4 +see +\fBCommon Options\fR\&. Requires +\fB\-a, \-\-allow\-overlaps\fR\&. +.RE +.PP +\fB\-R, \-\-regions\-file\fR \fIFILE\fR +.RS 4 +see +\fBCommon Options\fR\&. Requires +\fB\-a, \-\-allow\-overlaps\fR\&. +.RE +.PP +\fB\-\-threads\fR \fIINT\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.SS "bcftools consensus \fI[OPTIONS]\fR \fIFILE\fR" +.sp +Create consensus sequence by applying VCF variants to a reference fasta file\&. By default, the program will apply all ALT variants to the reference fasta to obtain the consensus sequence\&. Using the \fB\-\-sample\fR (and, optionally, \fB\-\-haplotype\fR) option will apply genotype (haplotype) calls from FORMAT/GT\&. Note that the program does not act as a primitive variant caller and ignores allelic depth information, such as INFO/AD or FORMAT/AD\&. For that, consider using the \fBsetGT\fR plugin\&. +.PP +\fB\-f, \-\-fasta\-ref\fR \fIFILE\fR +.RS 4 +reference sequence in fasta format +.RE +.PP +\fB\-H, \-\-haplotype\fR \fI1\fR|\fI2\fR +.RS 4 +apply variants for the given haplotype\&. This option requires +\fB\-s\fR, unless exactly one sample is present in the VCF +.RE +.PP +\fB\-i, \-\-iupac\-codes\fR +.RS 4 +output variants in the form of IUPAC ambiguity codes +.RE +.PP +\fB\-m, \-\-mask\fR \fIFILE\fR +.RS 4 +BED file or TAB file with regions to be replaced with N\&. See discussion of +\fB\-\-regions\-file\fR +in +\fBCommon Options\fR +for file format details\&. +.RE +.PP +\fB\-o, \-\-output\fR \fIFILE\fR +.RS 4 +write output to a file +.RE +.PP +\fB\-s, \-\-sample\fR \fINAME\fR +.RS 4 +apply variants of the given sample +.RE +.sp +\fBExamples:\fR +.sp +.if n \{\ +.RS 4 +.\} +.nf + # Apply variants present in sample "NA001", output IUPAC codes for hets + bcftools consensus \-i \-s NA001 \-f in\&.fa in\&.vcf\&.gz > out\&.fa + + # Create consensus for one region\&. The fasta header lines are then expected + # in the form ">chr:from\-to"\&. + samtools faidx ref\&.fa 8:11870\-11890 | bcftools consensus in\&.vcf\&.gz \-o out\&.fa +.fi +.if n \{\ +.RE +.\} +.SS "bcftools convert \fI[OPTIONS]\fR \fIFILE\fR" +.sp +.it 1 an-trap +.nr an-no-space-flag 1 +.nr an-break-flag 1 +.br +.ps +1 +\fBVCF input options:\fR +.RS 4 +.PP +\fB\-e, \-\-exclude\fR \fIEXPRESSION\fR +.RS 4 +exclude sites for which +\fIEXPRESSION\fR +is true\&. For valid expressions see +\fBEXPRESSIONS\fR\&. +.RE +.PP +\fB\-i, \-\-include\fR \fIEXPRESSION\fR +.RS 4 +include only sites for which +\fIEXPRESSION\fR +is true\&. For valid expressions see +\fBEXPRESSIONS\fR\&. +.RE +.PP +\fB\-r, \-\-regions\fR \fIchr\fR|\fIchr:pos\fR|\fIchr:from\-to\fR|\fIchr:from\-\fR[,\&...] +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-R, \-\-regions\-file\fR \fIFILE\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-s, \-\-samples\fR \fILIST\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-S, \-\-samples\-file\fR \fIFILE\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-t, \-\-targets\fR \fILIST\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-T, \-\-targets\-file\fR \fIFILE\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.RE +.sp +.it 1 an-trap +.nr an-no-space-flag 1 +.nr an-break-flag 1 +.br +.ps +1 +\fBVCF output options:\fR +.RS 4 +.PP +\fB\-\-no\-version\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-o, \-\-output\fR \fIFILE\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-O, \-\-output\-type\fR \fIb\fR|\fIu\fR|\fIz\fR|\fIv\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-\-threads\fR \fIINT\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.RE +.sp +.it 1 an-trap +.nr an-no-space-flag 1 +.nr an-break-flag 1 +.br +.ps +1 +\fBGEN/SAMPLE conversion:\fR +.RS 4 +.PP +\fB\-G, \-\-gensample2vcf\fR \fIprefix\fR or \fIgen\-file\fR,\fIsample\-file\fR +.RS 4 +convert IMPUTE2 output to VCF\&. The second column must be of the form "CHROM:POS_REF_ALT" to detect possible strand swaps; IMPUTE2 leaves the first one empty ("\-\-") when sites from reference panel are filled in\&. See also +\fB\-g\fR +below\&. +.RE +.PP +\fB\-g, \-\-gensample\fR \fIprefix\fR or \fIgen\-file\fR,\fIsample\-file\fR +.RS 4 +convert from VCF to gen/sample format used by IMPUTE2 and SHAPEIT\&. The columns of \&.gen file format are ID1,ID2,POS,A,B followed by three genotype probabilities P(AA), P(AB), P(BB) for each sample\&. In order to prevent strand swaps, the program uses IDs of the form "CHROM:POS_REF_ALT"\&. For example: +.RE +.sp +.if n \{\ +.RS 4 +.\} +.nf + \&.gen + \-\-\-\- + 1:111485207_G_A 1:111485207_G_A 111485207 G A 0 1 0 0 1 0 + 1:111494194_C_T 1:111494194_C_T 111494194 C T 0 1 0 0 0 1 + + \&.sample + \-\-\-\-\-\-\- + ID_1 ID_2 missing + 0 0 0 + sample1 sample1 0 + sample2 sample2 0 +.fi +.if n \{\ +.RE +.\} +.PP +\fB\-\-tag\fR \fISTRING\fR +.RS 4 +tag to take values for \&.gen file: GT,PL,GL,GP +.RE +.PP +\fB\-\-chrom\fR +.RS 4 +output chromosome in the first column instead of CHROM:POS_REF_ALT +.RE +.PP +\fB\-\-sex\fR \fIFILE\fR +.RS 4 +output sex column in the sample file\&. The FILE format is +.RE +.sp +.if n \{\ +.RS 4 +.\} +.nf + MaleSample M + FemaleSample F +.fi +.if n \{\ +.RE +.\} +.PP +\fB\-\-vcf\-ids\fR +.RS 4 +output VCF IDs in the second column instead of CHROM:POS_REF_ALT +.RE +.RE +.sp +.it 1 an-trap +.nr an-no-space-flag 1 +.nr an-break-flag 1 +.br +.ps +1 +\fBgVCF conversion:\fR +.RS 4 +.PP +\fB\-\-gvcf2vcf\fR +.RS 4 +convert gVCF to VCF, expanding REF blocks into sites\&. Only sites with FILTER set to "PASS" or "\&." will be expanded\&. +.RE +.PP +\fB\-f, \-\-fasta\-ref\fR \fIfile\fR +.RS 4 +reference sequence in fasta format\&. Must be indexed with samtools faidx +.RE +.RE +.sp +.it 1 an-trap +.nr an-no-space-flag 1 +.nr an-break-flag 1 +.br +.ps +1 +\fBHAPS/SAMPLE conversion:\fR +.RS 4 +.PP +\fB\-\-hapsample2vcf\fR \fIprefix\fR or \fIhaps\-file\fR,\fIsample\-file\fR +.RS 4 +convert from haps/sample format to VCF\&. The columns of \&.haps file are similar to \&.gen file above, but there are only two haplotype columns per sample\&. Note that the first column of the haps file is expected to be in the form "CHR:POS_REF_ALT(_END)?", with the _END being optional for defining the INFO/END tag when ALT is a symbolic allele, for example: +.RE +.sp +.if n \{\ +.RS 4 +.\} +.nf + \&.haps + \-\-\-\- + 1:111485207_G_A rsID1 111485207 G A 0 1 0 0 + 1:111494194_C_T rsID2 111494194 C T 0 1 0 0 + 1:111495231_A__111495784 rsID3 111495231 A 0 0 1 0 +.fi +.if n \{\ +.RE +.\} +.PP +\fB\-\-hapsample\fR \fIprefix\fR or \fIhaps\-file\fR,\fIsample\-file\fR +.RS 4 +convert from VCF to haps/sample format used by IMPUTE2 and SHAPEIT\&. The columns of \&.haps file begin with ID,RSID,POS,REF,ALT\&. In order to prevent strand swaps, the program uses IDs of the form "CHROM:POS_REF_ALT"\&. +.RE +.PP +\fB\-\-haploid2diploid\fR +.RS 4 +with +\fB\-h\fR +option converts haploid genotypes to homozygous diploid genotypes\&. For example, the program will print +\fI0 0\fR +instead of the default +\fI0 \-\fR\&. This is useful for programs which do not handle haploid genotypes correctly\&. +.RE +.PP +\fB\-\-sex\fR \fIFILE\fR +.RS 4 +output sex column in the sample file\&. The FILE format is +.RE +.sp +.if n \{\ +.RS 4 +.\} +.nf + MaleSample M + FemaleSample F +.fi +.if n \{\ +.RE +.\} +.PP +\fB\-\-vcf\-ids\fR +.RS 4 +output VCF IDs instead of "CHROM:POS_REF_ALT" IDs +.RE +.RE +.sp +.it 1 an-trap +.nr an-no-space-flag 1 +.nr an-break-flag 1 +.br +.ps +1 +\fBHAPS/LEGEND/SAMPLE conversion:\fR +.RS 4 +.PP +\fB\-H, \-\-haplegendsample2vcf\fR \fIprefix\fR or \fIhaps\-file\fR,\fIlegend\-file\fR,\fIsample\-file\fR +.RS 4 +convert from haps/legend/sample format used by IMPUTE2 to VCF, see also +\fB\-h, \-\-hapslegendsample\fR +below\&. +.RE +.PP +\fB\-h, \-\-haplegendsample\fR \fIprefix\fR or \fIhaps\-file\fR,\fIlegend\-file\fR,\fIsample\-file\fR +.RS 4 +convert from VCF to haps/legend/sample format used by IMPUTE2 and SHAPEIT\&. The columns of \&.legend file ID,POS,REF,ALT\&. In order to prevent strand swaps, the program uses IDs of the form "CHROM:POS_REF_ALT"\&. The \&.sample file is quite basic at the moment with columns for population, group and sex expected to be edited by the user\&. For example: +.RE +.sp +.if n \{\ +.RS 4 +.\} +.nf + \&.haps + \-\-\-\-\- + 0 1 0 0 1 0 + 0 1 0 0 0 1 + + \&.legend + \-\-\-\-\-\-\- + id position a0 a1 + 1:111485207_G_A 111485207 G A + 1:111494194_C_T 111494194 C T + + \&.sample + \-\-\-\-\-\-\- + sample population group sex + sample1 sample1 sample1 2 + sample2 sample2 sample2 2 +.fi +.if n \{\ +.RE +.\} +.PP +\fB\-\-haploid2diploid\fR +.RS 4 +with +\fB\-h\fR +option converts haploid genotypes to homozygous diploid genotypes\&. For example, the program will print +\fI0 0\fR +instead of the default +\fI0 \-\fR\&. This is useful for programs which do not handle haploid genotypes correctly\&. +.RE +.PP +\fB\-\-sex\fR \fIFILE\fR +.RS 4 +output sex column in the sample file\&. The FILE format is +.RE +.sp +.if n \{\ +.RS 4 +.\} +.nf + MaleSample M + FemaleSample F +.fi +.if n \{\ +.RE +.\} +.PP +\fB\-\-vcf\-ids\fR +.RS 4 +output VCF IDs instead of "CHROM:POS_REF_ALT" IDs +.RE +.RE +.sp +.it 1 an-trap +.nr an-no-space-flag 1 +.nr an-break-flag 1 +.br +.ps +1 +\fBTSV conversion:\fR +.RS 4 +.PP +\fB\-\-tsv2vcf\fR \fIfile\fR +.RS 4 +convert from TSV (tab\-separated values) format (such as generated by 23andMe) to VCF\&. The input file fields can be tab\- or space\- delimited +.RE +.PP +\fB\-c, \-\-columns\fR \fIlist\fR +.RS 4 +comma\-separated list of fields in the input file\&. In the current version, the fields CHROM, POS, ID, and AA are expected and can appear in arbitrary order, columns which should be ignored in the input file can be indicated by "\-"\&. The AA field lists alleles on the forward reference strand, for example "CC" or "CT" for diploid genotypes or "C" for haploid genotypes (sex chromosomes)\&. Insertions and deletions are not supported yet, missing data can be indicated with "\-\-"\&. +.RE +.PP +\fB\-f, \-\-fasta\-ref\fR \fIfile\fR +.RS 4 +reference sequence in fasta format\&. Must be indexed with samtools faidx +.RE +.PP +\fB\-s, \-\-samples\fR \fILIST\fR +.RS 4 +list of sample names\&. See +\fBCommon Options\fR +.RE +.PP +\fB\-S, \-\-samples\-file\fR \fIFILE\fR +.RS 4 +file of sample names\&. See +\fBCommon Options\fR +.RE +.sp +\fBExample:\fR +.sp +.if n \{\ +.RS 4 +.\} +.nf +# Convert 23andme results into VCF +bcftools convert \-c ID,CHROM,POS,AA \-s SampleName \-f 23andme\-ref\&.fa \-\-tsv2vcf 23andme\&.txt \-Oz \-o out\&.vcf\&.gz +.fi +.if n \{\ +.RE +.\} +.RE +.SS "bcftools csq \fI[OPTIONS]\fR \fIFILE\fR" +.sp +Haplotype aware consequence predictor which correctly handles combined variants such as MNPs split over multiple VCF records, SNPs separated by an intron (but adjacent in the spliced transcript) or nearby frame\-shifting indels which in combination in fact are not frame\-shifting\&. +.sp +The output VCF is annotated with INFO/BCSQ and FORMAT/BCSQ tag (configurable with the \fB\-c\fR option)\&. The latter is a bitmask of indexes to INFO/BCSQ, with interleaved haplotypes\&. See the usage examples below for using the %TBCSQ converter in \fBquery\fR for extracting a more human readable form from this bitmask\&. The contruction of the bitmask limits the number of consequences that can be referenced in the FORMAT/BCSQ tags\&. By default this is 16, but if more are required, see the \fB\-\-ncsq\fR option\&. +.sp +The program requires on input a VCF/BCF file, the reference genome in fasta format (\fB\-\-fasta\-ref\fR) and genomic features in the GFF3 format downloadable from the Ensembl website (\fB\-\-gff\-annot\fR), and outputs an annotated VCF/BCF file\&. Currently, only Ensembl GFF3 files are supported\&. +.sp +By default, the input VCF should be phased\&. If phase is unknown, or only partially known, the \fB\-\-phase\fR option can be used to indicate how to handle unphased data\&. Alternatively, haplotype aware calling can be turned off with the \fB\-\-local\-csq\fR option\&. +.sp +If conflicting (overlapping) variants within one haplotype are detected, a warning will be emitted and predictions will be based on only the first variant in the analysis\&. +.sp +Symbolic alleles are not supported\&. They will remain unannotated in the output VCF and are ignored for the prediction analysis\&. +.PP +\fB\-c, \-\-custom\-tag\fR \fISTRING\fR +.RS 4 +use this custom tag to store consequences rather than the default BCSQ tag +.RE +.PP +\fB\-e, \-\-exclude\fR \fIEXPRESSION\fR +.RS 4 +exclude sites for which +\fIEXPRESSION\fR +is true\&. For valid expressions see +\fBEXPRESSIONS\fR\&. +.RE +.PP +\fB\-f, \-\-fasta\-ref\fR \fIFILE\fR +.RS 4 +reference sequence in fasta format (required) +.RE +.PP +\fB\-g, \-\-gff\-annot\fR \fIFILE\fR +.RS 4 +GFF3 annotation file (required), such as +ftp://ftp\&.ensembl\&.org/pub/current_gff3/homo_sapiens/ +.RE +.PP +\fB\-i, \-\-include\fR \fIEXPRESSION\fR +.RS 4 +include only sites for which +\fIEXPRESSION\fR +is true\&. For valid expressions see +\fBEXPRESSIONS\fR\&. +.RE +.PP +\fB\-l, \-\-local\-csq\fR +.RS 4 +switch off haplotype\-aware calling, run localized predictions considering only one VCF record at a time +.RE +.PP +\fB\-n, \-\-ncsq\fR \fIINT\fR +.RS 4 +maximum number of consequences to consider per site\&. The INFO/BCSQ column includes all consequences, but only the first +\fIINT\fR +will be referenced by the FORMAT/BCSQ fields\&. The default value is 16 which corresponds to one integer per diploid sample\&. Note that increasing the value leads to increased memory and is rarely necessary\&. +.RE +.PP +\fB\-o, \-\-output\fR \fIFILE\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-O, \-\-output\-type\fR \fIb\fR|\fIt\fR|\fIu\fR|\fIz\fR|\fIv\fR +.RS 4 +see +\fBCommon Options\fR\&. In addition, a custom tab\-delimited plain text output can be printed (\fIt\fR)\&. +.RE +.PP +\fB\-p, \-\-phase\fR \fIa\fR|\fIm\fR|\fIr\fR|\fIR\fR|\fIs\fR +.RS 4 +how to construct haplotypes and how to deal with unphased data: +.PP +\fIa\fR +.RS 4 +take GTs as is, create haplotypes regardless of phase (0/1 → 0|1) +.RE +.PP +\fIm\fR +.RS 4 +merge all GTs into a single haplotype (0/1 → 1, 1/2 → 1) +.RE +.PP +\fIr\fR +.RS 4 +require phased GTs, throw an error on unphased heterozygous GTs +.RE +.PP +\fIR\fR +.RS 4 +create non\-reference haplotypes if possible (0/1 → 1|1, 1/2 → 1|2) +.RE +.PP +\fIs\fR +.RS 4 +skip unphased GTs +.RE +.RE +.PP +\fB\-q, \-\-quiet\fR +.RS 4 +suppress warning messages +.RE +.PP +\fB\-r, \-\-regions\fR \fIchr\fR|\fIchr:pos\fR|\fIchr:from\-to\fR|\fIchr:from\-\fR[,\&...] +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-R, \-\-regions\-file\fR \fIFILE\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-s, \-\-samples\fR \fILIST\fR +.RS 4 +samples to include or "\-" to apply all variants and ignore samples +.RE +.PP +\fB\-S, \-\-samples\-file\fR \fIFILE\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-t, \-\-targets\fR \fILIST\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-T, \-\-targets\-file\fR \fIFILE\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.sp +\fBExamples:\fR +.sp +.if n \{\ +.RS 4 +.\} +.nf + # Basic usage + bcftools csq \-f hs37d5\&.fa \-g Homo_sapiens\&.GRCh37\&.82\&.gff3\&.gz in\&.vcf \-Ob \-o out\&.bcf + + # Extract the translated haplotype consequences\&. The following TBCSQ variations + # are recognised: + # %TBCSQ \&.\&. print consequences in all haplotypes in separate columns + # %TBCSQ{0} \&.\&. print the first haplotype only + # %TBCSQ{1} \&.\&. print the second haplotype only + # %TBCSQ{*} \&.\&. print a list of unique consquences present in either haplotype + bcftools query \-f\*(Aq[%CHROM\et%POS\et%SAMPLE\et%TBCSQ\en]\*(Aq out\&.bcf +.fi +.if n \{\ +.RE +.\} +.sp +\fBExamples of BCSQ annotation:\fR +.sp +.if n \{\ +.RS 4 +.\} +.nf + # Two separate VCF records at positions 2:122106101 and 2:122106102 + # change the same codon\&. This UV\-induced C>T dinucleotide mutation + # has been annotated fully at the position 2:122106101 with + # \- consequence type + # \- gene name + # \- ensembl transcript ID + # \- coding strand (+ fwd, \- rev) + # \- amino acid position (in the coding strand orientation) + # \- list of corresponding VCF variants + # The annotation at the second position gives the position of the full + # annotation + BCSQ=missense|CLASP1|ENST00000545861|\-|1174P>1174L|122106101G>A+122106102G>A + BCSQ=@122106101 + + # A frame\-restoring combination of two frameshift insertions C>CG and T>TGG + BCSQ=@46115084 + BCSQ=inframe_insertion|COPZ2|ENST00000006101|\-|18AGRGP>18AQAGGP|46115072C>CG+46115084T>TGG + + # Stop gained variant + BCSQ=stop_gained|C2orf83|ENST00000264387|\-|141W>141*|228476140C>T + + # The consequence type of a variant downstream from a stop are prefixed with * + BCSQ=*missense|PER3|ENST00000361923|+|1028M>1028T|7890117T>C +.fi +.if n \{\ +.RE +.\} +.SS "bcftools filter \fI[OPTIONS]\fR \fIFILE\fR" +.sp +Apply fixed\-threshold filters\&. +.PP +\fB\-e, \-\-exclude\fR \fIEXPRESSION\fR +.RS 4 +exclude sites for which +\fIEXPRESSION\fR +is true\&. For valid expressions see +\fBEXPRESSIONS\fR\&. +.RE +.PP +\fB\-g, \-\-SnpGap\fR \fIINT\fR +.RS 4 +filter SNPs within +\fIINT\fR +base pairs of an indel\&. The following example demonstrates the logic of +\fB\-\-SnpGap\fR +\fI3\fR +applied on a deletion and an insertion: +.RE +.sp +.if n \{\ +.RS 4 +.\} +.nf +The SNPs at positions 1 and 7 are filtered, positions 0 and 8 are not: + 0123456789 + ref \&.G\&.GT\&.\&.G\&.\&. + del \&.A\&.G\-\&.\&.A\&.\&. +Here the positions 1 and 6 are filtered, 0 and 7 are not: + 0123\-456789 + ref \&.G\&.G\-\&.\&.G\&.\&. + ins \&.A\&.GT\&.\&.A\&.\&. +.fi +.if n \{\ +.RE +.\} +.PP +\fB\-G, \-\-IndelGap\fR \fIINT\fR +.RS 4 +filter clusters of indels separated by +\fIINT\fR +or fewer base pairs allowing only one to pass\&. The following example demonstrates the logic of +\fB\-\-IndelGap\fR +\fI2\fR +applied on a deletion and an insertion: +.RE +.sp +.if n \{\ +.RS 4 +.\} +.nf +The second indel is filtered: + 012345678901 + ref \&.GT\&.GT\&.\&.GT\&.\&. + del \&.G\-\&.G\-\&.\&.G\-\&.\&. +And similarly here, the second is filtered: + 01 23 456 78 + ref \&.A\-\&.A\-\&.\&.A\-\&.\&. + ins \&.AT\&.AT\&.\&.AT\&.\&. +.fi +.if n \{\ +.RE +.\} +.PP +\fB\-i, \-\-include\fR \fIEXPRESSION\fR +.RS 4 +include only sites for which +\fIEXPRESSION\fR +is true\&. For valid expressions see +\fBEXPRESSIONS\fR\&. +.RE +.PP +\fB\-m, \-\-mode\fR [\fI+x\fR] +.RS 4 +define behaviour at sites with existing FILTER annotations\&. The default mode replaces existing filters of failed sites with a new FILTER string while leaving sites which pass untouched when non\-empty and setting to "PASS" when the FILTER string is absent\&. The "+" mode appends new FILTER strings of failed sites instead of replacing them\&. The "x" mode resets filters of sites which pass to "PASS"\&. Modes "+" and "x" can both be set\&. +.RE +.PP +\fB\-\-no\-version\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-o, \-\-output\fR \fIFILE\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-O, \-\-output\-type\fR \fIb\fR|\fIu\fR|\fIz\fR|\fIv\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-r, \-\-regions\fR \fIchr\fR|\fIchr:pos\fR|\fIchr:from\-to\fR|\fIchr:from\-\fR[,\&...] +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-R, \-\-regions\-file\fR \fIfile\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-s, \-\-soft\-filter\fR \fISTRING\fR|\fI+\fR +.RS 4 +annotate FILTER column with +\fISTRING\fR +or, with +\fI+\fR, a unique filter name generated by the program ("Filter%d")\&. +.RE +.PP +\fB\-S, \-\-set\-GTs\fR \fI\&.\fR|\fI0\fR +.RS 4 +set genotypes of failed samples to missing value (\fI\&.\fR) or reference allele (\fI0\fR) +.RE +.PP +\fB\-t, \-\-targets\fR \fIchr\fR|\fIchr:pos\fR|\fIchr:from\-to\fR|\fIchr:from\-\fR[,\&...] +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-T, \-\-targets\-file\fR \fIfile\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-\-threads\fR \fIINT\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.SS "bcftools gtcheck [\fIOPTIONS\fR] [\-g \fIgenotypes\&.vcf\&.gz\fR] \fIquery\&.vcf\&.gz\fR" +.sp +Checks sample identity or, without \fB\-g\fR, multi\-sample cross\-check is performed\&. +.PP +\fB\-a, \-\-all\-sites\fR +.RS 4 +output for all sites +.RE +.PP +\fB\-c, \-\-cluster\fR \fIFLOAT\fR,\fIFLOAT\fR +.RS 4 +min inter\- and max intra\-sample error [0\&.23,\-0\&.3] +.sp +.if n \{\ +.RS 4 +.\} +.nf +The first "min" argument controls the typical error rate in multiplexed +runs ("lanelets") from the same sample\&. Lanelets with error rate less +than this will always be considered as coming from the same sample\&. +The second "max" argument is the reverse: lanelets with error rate +greater than the absolute value of this parameter will always be +considered as different samples\&. When the value is negative, the cutoff +may be heuristically lowered by the clustering engine\&. If positive, the +value is interpreted as a fixed cutoff\&. +.fi +.if n \{\ +.RE +.\} +.RE +.PP +\fB\-g, \-\-genotypes\fR \fIgenotypes\&.vcf\&.gz\fR +.RS 4 +reference genotypes to compare against +.RE +.PP +\fB\-G, \-\-GTs\-only\fR \fIINT\fR +.RS 4 +use genotypes (GT) instead of genotype likelihoods (PL)\&. When set to 1, reported discordance is the number of non\-matching GTs, otherwise the number +\fIINT\fR +is interpreted as phred\-scaled likelihood of unobserved genotypes\&. +.RE +.PP +\fB\-H, \-\-homs\-only\fR +.RS 4 +consider only genotypes which are homozygous in both +\fIgenotypes\fR +and +\fIquery\fR +VCF\&. This may be useful with low coverage data\&. +.RE +.PP +\fB\-p, \-\-plot\fR \fIPREFIX\fR +.RS 4 +produce plots +.RE +.PP +\fB\-r, \-\-regions\fR \fIchr\fR|\fIchr:pos\fR|\fIchr:from\-to\fR|\fIchr:from\-\fR[,\&...] +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-R, \-\-regions\-file\fR \fIfile\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-s, \-\-query\-sample\fR \fISTRING\fR +.RS 4 +query sample in +\fIquery\&.vcf\&.gz\fR\&. By default, the first sample is checked\&. +.RE +.PP +\fB\-S, \-\-target\-sample\fR \fISTRING\fR +.RS 4 +target sample in the +\fB\-g\fR +file, used only for plotting, not for analysis +.RE +.PP +\fB\-t, \-\-targets\fR \fIfile\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-T, \-\-targets\-file\fR \fIfile\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.sp +.it 1 an-trap +.nr an-no-space-flag 1 +.nr an-break-flag 1 +.br +.ps +1 +\fBOutput files format:\fR +.RS 4 +.PP +CN, Discordance +.RS 4 +Pairwise discordance for all sample pairs is calculated as +.RE +.sp +.if n \{\ +.RS 4 +.\} +.nf + \esum_s { min_G { PL_a(G) + PL_b(G) } }, +.fi +.if n \{\ +.RE +.\} +.PP +.RS 4 +where the sum runs over all sites +\fIs\fR +and +\fIG\fR +is the the most likely genotype shared by both samples +\fIa\fR +and +\fIb\fR\&. When PL field is not present, a constant value +\fI99\fR +is used for the unseen genotypes\&. With +\fB\-G\fR, the value +\fI1\fR +can be used instead; the discordance value then gives exactly the number of differing genotypes\&. +.RE +.PP +SM, Average Discordance +.RS 4 +Average discordance between sample +\fIa\fR +and all other samples\&. +.RE +.PP +SM, Average Depth +.RS 4 +Average depth at evaluated sites, or 1 if FORMAT/DP field is not present\&. +.RE +.PP +SM, Average Number of sites +.RS 4 +The average number of sites used to calculate the discordance\&. In other words, the average number of non\-missing PLs/genotypes seen both samples\&. +.RE +.RE +.SS "bcftools index [\fIOPTIONS\fR] \fIin\&.bcf\fR|\fIin\&.vcf\&.gz\fR" +.sp +Creates index for bgzip compressed VCF/BCF files for random access\&. CSI (coordinate\-sorted index) is created by default\&. The CSI format supports indexing of chromosomes up to length 2^31\&. TBI (tabix index) index files, which support chromosome lengths up to 2^29, can be created by using the \fI\-t/\-\-tbi\fR option or using the \fItabix\fR program packaged with htslib\&. When loading an index file, bcftools will try the CSI first and then the TBI\&. +.sp +.it 1 an-trap +.nr an-no-space-flag 1 +.nr an-break-flag 1 +.br +.ps +1 +\fBIndexing options:\fR +.RS 4 +.PP +\fB\-c, \-\-csi\fR +.RS 4 +generate CSI\-format index for VCF/BCF files [default] +.RE +.PP +\fB\-f, \-\-force\fR +.RS 4 +overwrite index if it already exists +.RE +.PP +\fB\-m, \-\-min\-shift \fR\fB\fIINT\fR\fR +.RS 4 +set minimal interval size for CSI indices to 2^INT; default: 14 +.RE +.PP +\fB\-o, \-\-output\-file \fR\fB\fIFILE\fR\fR +.RS 4 +output file name\&. If not set, then the index will be created using the input file name plus a +\fI\&.csi\fR +or +\fI\&.tbi\fR +extension +.RE +.PP +\fB\-t, \-\-tbi\fR +.RS 4 +generate TBI\-format index for VCF files +.RE +.PP +\fB\-\-threads\fR \fIINT\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.RE +.sp +.it 1 an-trap +.nr an-no-space-flag 1 +.nr an-break-flag 1 +.br +.ps +1 +\fBStats options:\fR +.RS 4 +.PP +\fB\-n, \-\-nrecords\fR +.RS 4 +print the number of records based on the CSI or TBI index files +.RE +.PP +\fB\-s, \-\-stats\fR +.RS 4 +Print per contig stats based on the CSI or TBI index files\&. Output format is three tab\-delimited columns listing the contig name, contig length (\fI\&.\fR +if unknown) and number of records for the contig\&. Contigs with zero records are not printed\&. +.RE +.RE +.SS "bcftools isec [\fIOPTIONS\fR] \fIA\&.vcf\&.gz\fR \fIB\&.vcf\&.gz\fR [\&...]" +.sp +Creates intersections, unions and complements of VCF files\&. Depending on the options, the program can output records from one (or more) files which have (or do not have) corresponding records with the same position in the other files\&. +.PP +\fB\-c, \-\-collapse\fR \fIsnps\fR|\fIindels\fR|\fIboth\fR|\fIall\fR|\fIsome\fR|\fInone\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-C, \-\-complement\fR +.RS 4 +output positions present only in the first file but missing in the others +.RE +.PP +\fB\-e, \-\-exclude\fR \fI\-\fR|\fIEXPRESSION\fR +.RS 4 +exclude sites for which +\fIEXPRESSION\fR +is true\&. If +\fB\-e\fR +(or +\fB\-i\fR) appears only once, the same filtering expression will be applied to all input files\&. Otherwise, +\fB\-e\fR +or +\fB\-i\fR +must be given for each input file\&. To indicate that no filtering should be performed on a file, use "\-" in place of +\fIEXPRESSION\fR, as shown in the example below\&. For valid expressions see +\fBEXPRESSIONS\fR\&. +.RE +.PP +\fB\-f, \-\-apply\-filters\fR \fILIST\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-i, \-\-include\fR \fIEXPRESSION\fR +.RS 4 +include only sites for which +\fIEXPRESSION\fR +is true\&. See discussion of +\fB\-e, \-\-exclude\fR +above\&. +.RE +.PP +\fB\-n, \-\-nfiles\fR [+\-=]\fIINT\fR|~\fIBITMAP\fR +.RS 4 +output positions present in this many (=), this many or more (+), this many or fewer (\-), or the exact same (~) files +.RE +.PP +\fB\-o, \-\-output\fR \fIFILE\fR +.RS 4 +see +\fBCommon Options\fR\&. When several files are being output, their names are controlled via +\fB\-p\fR +instead\&. +.RE +.PP +\fB\-O, \-\-output\-type\fR \fIb\fR|\fIu\fR|\fIz\fR|\fIv\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-p, \-\-prefix\fR \fIDIR\fR +.RS 4 +if given, subset each of the input files accordingly\&. See also +\fB\-w\fR\&. +.RE +.PP +\fB\-r, \-\-regions\fR \fIchr\fR|\fIchr:pos\fR|\fIchr:from\-to\fR|\fIchr:from\-\fR[,\&...] +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-R, \-\-regions\-file\fR \fIfile\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-t, \-\-targets\fR \fIchr\fR|\fIchr:pos\fR|\fIchr:from\-to\fR|\fIchr:from\-\fR[,\&...] +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-T, \-\-targets\-file\fR \fIfile\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-w, \-\-write\fR \fILIST\fR +.RS 4 +list of input files to output given as 1\-based indices\&. With +\fB\-p\fR +and no +\fB\-w\fR, all files are written\&. +.RE +.sp +.it 1 an-trap +.nr an-no-space-flag 1 +.nr an-break-flag 1 +.br +.ps +1 +\fBExamples:\fR +.RS 4 +.sp +Create intersection and complements of two sets saving the output in dir/* +.sp +.if n \{\ +.RS 4 +.\} +.nf + bcftools isec \-p dir A\&.vcf\&.gz B\&.vcf\&.gz +.fi +.if n \{\ +.RE +.\} +.sp +Filter sites in A and B (but not in C) and create intersection +.sp +.if n \{\ +.RS 4 +.\} +.nf + bcftools isec \-e\*(AqMAF<0\&.01\*(Aq \-i\*(AqdbSNP=1\*(Aq \-e\- A\&.vcf\&.gz B\&.vcf\&.gz C\&.vcf\&.gz \-p dir +.fi +.if n \{\ +.RE +.\} +.sp +Extract and write records from A shared by both A and B using exact allele match +.sp +.if n \{\ +.RS 4 +.\} +.nf + bcftools isec \-p dir \-n=2 \-w1 A\&.vcf\&.gz B\&.vcf\&.gz +.fi +.if n \{\ +.RE +.\} +.sp +Extract records private to A or B comparing by position only +.sp +.if n \{\ +.RS 4 +.\} +.nf + bcftools isec \-p dir \-n\-1 \-c all A\&.vcf\&.gz B\&.vcf\&.gz +.fi +.if n \{\ +.RE +.\} +.sp +Print a list of records which are present in A and B but not in C and D +.sp +.if n \{\ +.RS 4 +.\} +.nf + bcftools isec \-n~1100 \-c all A\&.vcf\&.gz B\&.vcf\&.gz C\&.vcf\&.gz D\&.vcf\&.gz +.fi +.if n \{\ +.RE +.\} +.RE +.SS "bcftools merge [\fIOPTIONS\fR] \fIA\&.vcf\&.gz\fR \fIB\&.vcf\&.gz\fR [\&...]" +.sp +Merge multiple VCF/BCF files from non\-overlapping sample sets to create one multi\-sample file\&. For example, when merging file \fIA\&.vcf\&.gz\fR containing samples \fIS1\fR, \fIS2\fR and \fIS3\fR and file \fIB\&.vcf\&.gz\fR containing samples \fIS3\fR and \fIS4\fR, the output file will contain four samples named \fIS1\fR, \fIS2\fR, \fIS3\fR, \fI2:S3\fR and \fIS4\fR\&. +.sp +Note that it is responsibility of the user to ensure that the sample names are unique across all files\&. If they are not, the program will exit with an error unless the option \fB\-\-force\-samples\fR is given\&. The sample names can be also given explicitly using the \fB\-\-print\-header\fR and \fB\-\-use\-header\fR options\&. +.sp +Note that only records from different files can be merged, never from the same file\&. For "vertical" merge take a look at \fBbcftools norm\fR instead\&. +.PP +\fB\-\-force\-samples\fR +.RS 4 +if the merged files contain duplicate samples names, proceed anyway\&. Duplicate sample names will be resolved by prepending index of the file as it appeared on the command line to the conflicting sample name (see +\fI2:S3\fR +in the above example)\&. +.RE +.PP +\fB\-\-print\-header\fR +.RS 4 +print only merged header and exit +.RE +.PP +\fB\-\-use\-header\fR \fIFILE\fR +.RS 4 +use the VCF header in the provided text +\fIFILE\fR +.RE +.PP +\fB\-0 \-\-missing\-to\-ref\fR +.RS 4 +assume genotypes at missing sites are 0/0 +.RE +.PP +\fB\-f, \-\-apply\-filters\fR \fILIST\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-F, \-\-filter\-logic\fR \fIx\fR|\fI+\fR +.RS 4 +Set the output record to PASS if any of the inputs is PASS (\fIx\fR), or apply all filters (\fI+\fR), which is the default\&. +.RE +.PP +\fB\-g, \-\-gvcf\fR \fI\-\fR|\fIFILE\fR +.RS 4 +merge gVCF blocks, INFO/END tag is expected\&. If the reference fasta file +\fIFILE\fR +is not given and the dash (\fI\-\fR) is given, unknown reference bases generated at gVCF block splits will be substituted with N\(cqs\&. The +\fB\-\-gvcf\fR +option uses the following default INFO rules: +\fB\-i QS:sum,MinDP:min,I16:sum,IDV:max,IMF:max\fR\&. +.RE +.PP +\fB\-i, \-\-info\-rules\fR \fI\-\fR|\fITAG:METHOD\fR[,\&...] +.RS 4 +Rules for merging INFO fields (scalars or vectors) or +\fI\-\fR +to disable the default rules\&. +\fIMETHOD\fR +is one of +\fIsum\fR, +\fIavg\fR, +\fImin\fR, +\fImax\fR, +\fIjoin\fR\&. Default is +\fIDP:sum,DP4:sum\fR +if these fields exist in the input files\&. Fields with no specified rule will take the value from the first input file\&. The merged QUAL value is currently set to the maximum\&. This behaviour is not user controllable at the moment\&. +.RE +.PP +\fB\-l, \-\-file\-list\fR \fIFILE\fR +.RS 4 +Read file names from +\fIFILE\fR, one file name per line\&. +.RE +.PP +\fB\-m, \-\-merge\fR \fIsnps\fR|\fIindels\fR|\fIboth\fR|\fIall\fR|\fInone\fR|\fIid\fR +.RS 4 +The option controls what types of multiallelic records can be created: +.RE +.sp +.if n \{\ +.RS 4 +.\} +.nf +\-m none \&.\&. no new multiallelics, output multiple records instead +\-m snps \&.\&. allow multiallelic SNP records +\-m indels \&.\&. allow multiallelic indel records +\-m both \&.\&. both SNP and indel records can be multiallelic +\-m all \&.\&. SNP records can be merged with indel records +\-m id \&.\&. merge by ID +.fi +.if n \{\ +.RE +.\} +.PP +\fB\-\-no\-version\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-o, \-\-output\fR \fIFILE\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-O, \-\-output\-type\fR \fIb\fR|\fIu\fR|\fIz\fR|\fIv\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-r, \-\-regions\fR \fIchr\fR|\fIchr:pos\fR|\fIchr:from\-to\fR|\fIchr:from\-\fR[,\&...] +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-R, \-\-regions\-file\fR \fIfile\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-\-threads\fR \fIINT\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.SS "bcftools mpileup [\fIOPTIONS\fR] \-f \fIref\&.fa\fR \fIin\&.bam\fR [\fIin2\&.bam\fR [\&...]]" +.sp +Generate VCF or BCF containing genotype likelihoods for one or multiple alignment (BAM or CRAM) files\&. This is based on the original \fBsamtools mpileup\fR command (with the \fB\-v\fR or \fB\-g\fR options) producing genotype likelihoods in VCF or BCF format, but not the textual pileup output\&. The \fBmpileup\fR command was transferred to bcftools in order to avoid errors resulting from use of incompatible versions of samtools and bcftools when using in the mpileup+bcftools call pipeline\&. +.sp +Individuals are identified from the SM tags in the @RG header lines\&. Multiple individuals can be pooled in one alignment file, also one individual can be separated into multiple files\&. If sample identifiers are absent, each input file is regarded as one sample\&. +.sp +Note that there are two orthogonal ways to specify locations in the input file; via \fB\-r\fR \fIregion\fR and \fB\-t\fR \fIpositions\fR\&. The former uses (and requires) an index to do random access while the latter streams through the file contents filtering out the specified regions, requiring no index\&. The two may be used in conjunction\&. For example a BED file containing locations of genes in chromosome 20 could be specified using \fB\-r 20 \-t chr20\&.bed\fR, meaning that the index is used to find chromosome 20 and then it is filtered for the regions listed in the BED file\&. Also note that the \fB\-r\fR option can be much slower than \fB\-t\fR with many regions and can require more memory when multiple regions and many alignment files are processed\&. +.sp +.it 1 an-trap +.nr an-no-space-flag 1 +.nr an-break-flag 1 +.br +.ps +1 +\fBInput options\fR +.RS 4 +.PP +\fB\-6, \-\-illumina1\&.3+\fR +.RS 4 +Assume the quality is in the Illumina 1\&.3+ encoding\&. +.RE +.PP +\fB\-A, \-\-count\-orphans\fR +.RS 4 +Do not skip anomalous read pairs in variant calling\&. +.RE +.PP +\fB\-b, \-\-bam\-list\fR \fIFILE\fR +.RS 4 +List of input alignment files, one file per line [null] +.RE +.PP +\fB\-B, \-\-no\-BAQ\fR +.RS 4 +Disable probabilistic realignment for the computation of base alignment quality (BAQ)\&. BAQ is the Phred\-scaled probability of a read base being misaligned\&. Applying this option greatly helps to reduce false SNPs caused by misalignments\&. +.RE +.PP +\fB\-C, \-\-adjust\-MQ\fR \fIINT\fR +.RS 4 +Coefficient for downgrading mapping quality for reads containing excessive mismatches\&. Given a read with a phred\-scaled probability q of being generated from the mapped posi\- tion, the new mapping quality is about sqrt((INT\-q)/INT)*INT\&. A zero value disables this functionality; if enabled, the recommended value for BWA is 50\&. [0] +.RE +.PP +\fB\-d, \-\-max\-depth\fR \fIINT\fR +.RS 4 +At a position, read maximally +\fIINT\fR +reads per input file\&. Note that bcftools has a minimum value of +\fI8000/n\fR +where +\fIn\fR +is the number of input files given to mpileup\&. This means the default is highly likely to be increased\&. Once above the cross\-sample minimum of 8000 the \-d parameter will have an effect\&. [250] +.RE +.PP +\fB\-E, \-\-redo\-BAQ\fR +.RS 4 +Recalculate BAQ on the fly, ignore existing BQ tags +.RE +.PP +\fB\-f, \-\-fasta\-ref\fR \fIFILE\fR +.RS 4 +The +\fBfaidx\fR\-indexed reference file in the FASTA format\&. The file can be optionally compressed by +\fBbgzip\fR\&. Reference is required by default unless the +\fB\-\-no\-reference\fR +option is set [null] +.RE +.PP +\fB\-\-no\-reference\fR +.RS 4 +Do not require the +\fB\-\-fasta\-ref\fR +option\&. +.RE +.PP +\fB\-G, \-\-read\-groups\fR \fIFILE\fR +.RS 4 +list of read groups to include or exclude if prefixed with "^"\&. One read group per line\&. This file can also be used to assign new sample names to read groups by giving the new sample name as a second white\-space\-separated field, like this: "read_group_id new_sample_name"\&. If the read group name is not unique, also the bam file name can be included: "read_group_id file_name sample_name"\&. If all reads from the alignment file should be treated as a single sample, the asterisk symbol can be used: "* file_name sample_name"\&. Alignments without a read group ID can be matched with "?"\&. +.RE +.sp +.if n \{\ +.RS 4 +.\} +.nf + RG_ID_1 + RG_ID_2 SAMPLE_A + RG_ID_3 SAMPLE_A + RG_ID_4 SAMPLE_B + RG_ID_5 FILE_1\&.bam SAMPLE_A + RG_ID_6 FILE_2\&.bam SAMPLE_A + * FILE_3\&.bam SAMPLE_C + ? FILE_3\&.bam SAMPLE_D +.fi +.if n \{\ +.RE +.\} +.PP +\fB\-q, \-min\-MQ\fR \fIINT\fR +.RS 4 +Minimum mapping quality for an alignment to be used [0] +.RE +.PP +\fB\-Q, \-\-min\-BQ\fR \fIINT\fR +.RS 4 +Minimum base quality for a base to be considered [13] +.RE +.PP +\fB\-r, \-\-regions\fR \fICHR\fR|\fICHR:POS\fR|\fICHR:FROM\-TO\fR|\fICHR:FROM\-\fR[,\&...] +.RS 4 +Only generate mpileup output in given regions\&. Requires the alignment files to be indexed\&. If used in conjunction with \-l then considers the intersection; see +\fBCommon Options\fR +.RE +.PP +\fB\-R, \-\-regions\-file\fR \fIFILE\fR +.RS 4 +As for +\fB\-r, \-\-regions\fR, but regions read from FILE; see +\fBCommon Options\fR +.RE +.PP +\fB\-\-ignore\-RG\fR +.RS 4 +Ignore RG tags\&. Treat all reads in one alignment file as one sample\&. +.RE +.PP +\fB\-\-rf, \-\-incl\-flags\fR \fISTR\fR|\fIINT\fR +.RS 4 +Required flags: skip reads with mask bits unset [null] +.RE +.PP +\fB\-\-ff, \-\-excl\-flags\fR \fISTR\fR|\fIINT\fR +.RS 4 +Filter flags: skip reads with mask bits set [UNMAP,SECONDARY,QCFAIL,DUP] +.RE +.PP +\fB\-s, \-\-samples\fR \fILIST\fR +.RS 4 +list of sample names\&. See +\fBCommon Options\fR +.RE +.PP +\fB\-S, \-\-samples\-file\fR \fIFILE\fR +.RS 4 +file of sample names to include or exclude if prefixed with "^"\&. One sample per line\&. This file can also be used to rename samples by giving the new sample name as a second white\-space\-separated column, like this: "old_name new_name"\&. If a sample name contains spaces, the spaces can be escaped using the backslash character, for example "Not\e a\e good\e sample\e name"\&. +.RE +.PP +\fB\-t, \-\-targets\fR \fILIST\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-T, \-\-targets\-file\fR \fIFILE\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-x, \-\-ignore\-overlaps\fR +.RS 4 +Disable read\-pair overlap detection\&. +.RE +.RE +.sp +.it 1 an-trap +.nr an-no-space-flag 1 +.nr an-break-flag 1 +.br +.ps +1 +\fBOutput options\fR +.RS 4 +.PP +\fB\-a, \-\-annotate\fR \fILIST\fR +.RS 4 +Comma\-separated list of FORMAT and INFO tags to output\&. (case\-insensitive, the "FORMAT/" prefix is optional, and use "?" to list available annotations on the command line) [null]: +.sp +.if n \{\ +.RS 4 +.\} +.nf +*FORMAT/AD* \&.\&. Allelic depth (Number=R,Type=Integer) +*FORMAT/ADF* \&.\&. Allelic depths on the forward strand (Number=R,Type=Integer) +*FORMAT/ADR* \&.\&. Allelic depths on the reverse strand (Number=R,Type=Integer) +*FORMAT/DP* \&.\&. Number of high\-quality bases (Number=1,Type=Integer) +*FORMAT/SP* \&.\&. Phred\-scaled strand bias P\-value (Number=1,Type=Integer) +.fi +.if n \{\ +.RE +.\} +.sp +.if n \{\ +.RS 4 +.\} +.nf +*INFO/AD* \&.\&. Total allelic depth (Number=R,Type=Integer) +*INFO/ADF* \&.\&. Total allelic depths on the forward strand (Number=R,Type=Integer) +*INFO/ADR* \&.\&. Total allelic depths on the reverse strand (Number=R,Type=Integer) +.fi +.if n \{\ +.RE +.\} +.sp +.if n \{\ +.RS 4 +.\} +.nf +*FORMAT/DV* \&.\&. Deprecated in favor of FORMAT/AD; + Number of high\-quality non\-reference bases, (Number=1,Type=Integer) +*FORMAT/DP4* \&.\&. Deprecated in favor of FORMAT/ADF and FORMAT/ADR; + Number of high\-quality ref\-forward, ref\-reverse, + alt\-forward and alt\-reverse bases (Number=4,Type=Integer) +*FORMAT/DPR* \&.\&. Deprecated in favor of FORMAT/AD; + Number of high\-quality bases for each observed allele (Number=R,Type=Integer) +*INFO/DPR* \&.\&. Deprecated in favor of INFO/AD; + Number of high\-quality bases for each observed allele (Number=R,Type=Integer) +.fi +.if n \{\ +.RE +.\} +.RE +.PP +\fB\-g, \-\-gvcf\fR \fIINT\fR[,\&...] +.RS 4 +output gVCF blocks of homozygous REF calls, with depth (DP) ranges specified by the list of integers\&. For example, passing +\fI5,15\fR +will group sites into two types of gVCF blocks, the first with minimum per\-sample DP from the interval [5,15) and the latter with minimum depth 15 or more\&. In this example, sites with minimum per\-sample depth less than 5 will be printed as separate records, outside of gVCF blocks\&. +.RE +.PP +\fB\-\-no\-version\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-o, \-\-output\fR \fIFILE\fR +.RS 4 +Write output to +\fIFILE\fR, rather than the default of standard output\&. (The same short option is used for both +\fB\-\-open\-prob\fR +and +\fB\-\-output\fR\&. If +\fB\-o\fR\*(Aqs argument contains any non\-digit characters other than a leading + or \- sign, it is interpreted as +\fB\-\-output\fR\&. Usually the filename extension will take care of this, but to write to an entirely numeric filename use +\fB\-o \&./123\fR +or +\fB\-\-output 123\fR\&.) +.RE +.PP +\fB\-O, \-\-output\-type\fR \fIb\fR|\fIu\fR|\fIz\fR|\fIv\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-\-threads\fR \fIINT\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.RE +.sp +.it 1 an-trap +.nr an-no-space-flag 1 +.nr an-break-flag 1 +.br +.ps +1 +\fBOptions for SNP/INDEL genotype likelihood computation\fR +.RS 4 +.PP +\fB\-e, \-\-ext\-prob\fR \fIINT\fR +.RS 4 +Phred\-scaled gap extension sequencing error probability\&. Reducing +\fIINT\fR +leads to longer indels [20] +.RE +.PP +\fB\-F, \-\-gap\-frac\fR \fIFLOAT\fR +.RS 4 +Minimum fraction of gapped reads [0\&.002] +.RE +.PP +\fB\-h, \-\-tandem\-qual\fR \fIINT\fR +.RS 4 +Coefficient for modeling homopolymer errors\&. Given an +\fIl\fR\-long homopolymer run, the sequencing error of an indel of size s is modeled as +\fIINT\fR*s/l [100] +.RE +.PP +\fB\-I, \-\-skip\-indels\fR +.RS 4 +Do not perform INDEL calling +.RE +.PP +\fB\-L, \-\-max\-idepth\fR \fIINT\fR +.RS 4 +Skip INDEL calling if the average per\-sample depth is above +\fIINT\fR +[250] +.RE +.PP +\fB\-m, \-\-min\-ireads\fR \fIINT\fR +.RS 4 +Minimum number gapped reads for indel candidates +\fIINT\fR +[1] +.RE +.PP +\fB\-o, \-\-open\-prob\fR \fIINT\fR +.RS 4 +Phred\-scaled gap open sequencing error probability\&. Reducing +\fIINT\fR +leads to more indel calls\&. (The same short option is used for both +\fB\-\-open\-prob\fR +and +\fB\-\-output\fR\&. When \-o\(cqs argument contains only an optional + or \- sign followed by the digits 0 to 9, it is interpreted as +\fB\-\-open\-prob\fR\&.) [40] +.RE +.PP +\fB\-p, \-\-per\-sample\-mF\fR +.RS 4 +Apply +\fB\-m\fR +and +\fB\-F\fR +thresholds per sample to increase sensitivity of calling\&. By default both options are applied to reads pooled from all samples\&. +.RE +.PP +\fB\-P, \-\-platforms\fR \fISTR\fR +.RS 4 +Comma\-delimited list of platforms (determined by +\fB@RG\-PL\fR) from which indel candidates are obtained\&. It is recommended to collect indel candidates from sequencing technologies that have low indel error rate such as ILLUMINA [all] +.RE +.RE +.sp +.it 1 an-trap +.nr an-no-space-flag 1 +.nr an-break-flag 1 +.br +.ps +1 +\fBExamples:\fR +.RS 4 +.sp +Call SNPs and short INDELs, then mark low quality sites and sites with the read depth exceeding a limit\&. (The read depth should be adjusted to about twice the average read depth as higher read depths usually indicate problematic regions which are often enriched for artefacts\&.) One may consider to add \fB\-C50\fR to mpileup if mapping quality is overestimated for reads containing excessive mismatches\&. Applying this option usually helps for BWA\-backtrack alignments, but may not other aligners\&. +.sp +.if n \{\ +.RS 4 +.\} +.nf + bcftools mpileup \-Ou \-f ref\&.fa aln\&.bam | \e + bcftools call \-Ou \-mv | \e + bcftools filter \-s LowQual \-e \*(Aq%QUAL<20 || DP>100\*(Aq > var\&.flt\&.vcf +.fi +.if n \{\ +.RE +.\} +.RE +.SS "bcftools norm [\fIOPTIONS\fR] \fIfile\&.vcf\&.gz\fR" +.sp +Left\-align and normalize indels, check if REF alleles match the reference, split multiallelic sites into multiple rows; recover multiallelics from multiple rows\&. Left\-alignment and normalization will only be applied if the \fB\-\-fasta\-ref\fR option is supplied\&. +.PP +\fB\-c, \-\-check\-ref\fR \fIe\fR|\fIw\fR|\fIx\fR|\fIs\fR +.RS 4 +what to do when incorrect or missing REF allele is encountered: exit (\fIe\fR), warn (\fIw\fR), exclude (\fIx\fR), or set/fix (\fIs\fR) bad sites\&. The +\fIw\fR +option can be combined with +\fIx\fR +and +\fIs\fR\&. Note that +\fIs\fR +can swap alleles and will update genotypes (GT) and AC counts, but will not attempt to fix PL or other fields\&. +.RE +.PP +\fB\-d, \-\-rm\-dup\fR \fIsnps\fR|\fIindels\fR|\fIboth\fR|\fIall\fR|\fInone\fR +.RS 4 +If a record is present multiple times, output only the first instance, see +\fB\-\-collapse\fR +in +\fBCommon Options\fR\&. Requires +\fB\-a, \-\-allow\-overlaps\fR\&. +.RE +.PP +\fB\-D, \-\-remove\-duplicates\fR +.RS 4 +If a record is present in multiple files, output only the first instance\&. Alias for +\fB\-d none\fR\&. Requires +\fB\-a, \-\-allow\-overlaps\fR\&. +.RE +.PP +\fB\-f, \-\-fasta\-ref\fR \fIFILE\fR +.RS 4 +reference sequence\&. Supplying this option will turn on left\-alignment and normalization, however, see also the +\fB\-\-do\-not\-normalize\fR +option below\&. +.RE +.PP +\fB\-m, \-\-multiallelics\fR \fB\-\fR|\fB+\fR[\fIsnps\fR|\fIindels\fR|\fIboth\fR|\fIany\fR] +.RS 4 +split multiallelic sites into biallelic records (\fB\-\fR) or join biallelic sites into multiallelic records (\fB+\fR)\&. An optional type string can follow which controls variant types which should be split or merged together: If only SNP records should be split or merged, specify +\fIsnps\fR; if both SNPs and indels should be merged separately into two records, specify +\fIboth\fR; if SNPs and indels should be merged into a single record, specify +\fIany\fR\&. +.RE +.PP +\fB\-\-no\-version\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-N, \-\-do\-not\-normalize\fR +.RS 4 +the +\fI\-c s\fR +option can be used to fix or set the REF allele from the reference +\fI\-f\fR\&. The +\fI\-N\fR +option will not turn on indel normalisation as the +\fI\-f\fR +option normally implies +.RE +.PP +\fB\-o, \-\-output\fR \fIFILE\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-O, \-\-output\-type\fR \fIb\fR|\fIu\fR|\fIz\fR|\fIv\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-r, \-\-regions\fR \fIchr\fR|\fIchr:pos\fR|\fIchr:from\-to\fR|\fIchr:from\-\fR[,\&...] +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-R, \-\-regions\-file\fR \fIfile\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-s, \-\-strict\-filter\fR +.RS 4 +when merging (\fI\-m+\fR), merged site is PASS only if all sites being merged PASS +.RE +.PP +\fB\-t, \-\-targets\fR \fILIST\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-T, \-\-targets\-file\fR \fIFILE\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-\-threads\fR \fIINT\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-w, \-\-site\-win\fR \fIINT\fR +.RS 4 +maximum distance between two records to consider when locally sorting variants which changed position during the realignment +.RE +.SS "bcftools [plugin \fINAME\fR|+\fINAME\fR] \fI[OPTIONS]\fR \fIFILE\fR \(em \fI[PLUGIN OPTIONS]\fR" +.sp +A common framework for various utilities\&. The plugins can be used the same way as normal commands only their name is prefixed with "+"\&. Most plugins accept two types of parameters: general options shared by all plugins followed by a separator, and a list of plugin\-specific options\&. There are some exceptions to this rule, some plugins do not accept the common options and implement their own parameters\&. Therefore please pay attention to the usage examples that each plugin comes with\&. +.sp +.it 1 an-trap +.nr an-no-space-flag 1 +.nr an-break-flag 1 +.br +.ps +1 +\fBVCF input options:\fR +.RS 4 +.PP +\fB\-e, \-\-exclude\fR \fIEXPRESSION\fR +.RS 4 +exclude sites for which +\fIEXPRESSION\fR +is true\&. For valid expressions see +\fBEXPRESSIONS\fR\&. +.RE +.PP +\fB\-i, \-\-include\fR \fIEXPRESSION\fR +.RS 4 +include only sites for which +\fIEXPRESSION\fR +is true\&. For valid expressions see +\fBEXPRESSIONS\fR\&. +.RE +.PP +\fB\-r, \-\-regions\fR \fIchr\fR|\fIchr:pos\fR|\fIchr:from\-to\fR|\fIchr:from\-\fR[,\&...] +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-R, \-\-regions\-file\fR \fIfile\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-t, \-\-targets\fR \fIchr\fR|\fIchr:pos\fR|\fIchr:from\-to\fR|\fIchr:from\-\fR[,\&...] +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-T, \-\-targets\-file\fR \fIfile\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.RE +.sp +.it 1 an-trap +.nr an-no-space-flag 1 +.nr an-break-flag 1 +.br +.ps +1 +\fBVCF output options:\fR +.RS 4 +.PP +\fB\-\-no\-version\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-o, \-\-output\fR \fIFILE\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-O, \-\-output\-type\fR \fIb\fR|\fIu\fR|\fIz\fR|\fIv\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-\-threads\fR \fIINT\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.RE +.sp +.it 1 an-trap +.nr an-no-space-flag 1 +.nr an-break-flag 1 +.br +.ps +1 +\fBPlugin options:\fR +.RS 4 +.PP +\fB\-h, \-\-help\fR +.RS 4 +list plugin\(cqs options +.RE +.PP +\fB\-l, \-\-list\-plugins\fR +.RS 4 +List all available plugins\&. +.sp +By default, appropriate system directories are searched for installed plugins\&. You can override this by setting the BCFTOOLS_PLUGINS environment variable to a colon\-separated list of directories to search\&. If BCFTOOLS_PLUGINS begins with a colon, ends with a colon, or contains adjacent colons, the system directories are also searched at that position in the list of directories\&. +.RE +.PP +\fB\-v, \-\-verbose\fR +.RS 4 +print debugging information to debug plugin failure +.RE +.PP +\fB\-V, \-\-version\fR +.RS 4 +print version string and exit +.RE +.RE +.sp +.it 1 an-trap +.nr an-no-space-flag 1 +.nr an-break-flag 1 +.br +.ps +1 +\fBList of plugins coming with the distribution:\fR +.RS 4 +.PP +\fBGTisec\fR +.RS 4 +count genotype intersections across all possible sample subsets in a vcf file +.RE +.PP +\fBGTsubset\fR +.RS 4 +output only sites where the requested samples all exclusively share a genotype +.RE +.PP +\fBad\-bias\fR +.RS 4 +find positions with wildly varying ALT allele frequency (Fisher test on FMT/AD) +.RE +.PP +\fBaf\-dist\fR +.RS 4 +collect AF deviation stats and GT probability distribution given AF and assuming HWE +.RE +.PP +\fBcolor\-chrs\fR +.RS 4 +color shared chromosomal segments, requires trio VCF with phased GTs +.RE +.PP +\fBcounts\fR +.RS 4 +a minimal plugin which counts number of SNPs, Indels, and total number of sites\&. +.RE +.PP +\fBdosage\fR +.RS 4 +print genotype dosage\&. By default the plugin searches for PL, GL and GT, in that order\&. +.RE +.PP +\fBfill\-AN\-AC\fR +.RS 4 +fill INFO fields AN and AC\&. +.RE +.PP +\fBfill\-from\-fasta\fR +.RS 4 +fill INFO or REF field based on values in a fasta file +.RE +.PP +\fBfill\-tags\fR +.RS 4 +set INFO tags AF, AN, AC, NS, AC_Hom, AC_Het, AC_Hemi +.RE +.PP +\fBfix\-ploidy\fR +.RS 4 +sets correct ploidy +.RE +.PP +\fBfixref\fR +.RS 4 +determine and fix strand orientation +.RE +.PP +\fBframeshifts\fR +.RS 4 +annotate frameshift indels +.RE +.PP +\fBguess\-ploidy\fR +.RS 4 +determine sample sex by checking genotype likelihoods (GL,PL) or genotypes (GT) in the non\-PAR region of chrX\&. +.RE +.PP +\fBimpute\-info\fR +.RS 4 +add imputation information metrics to the INFO field based on selected FORMAT tags +.RE +.PP +\fBmendelian\fR +.RS 4 +count Mendelian consistent / inconsistent genotypes\&. +.RE +.PP +\fBmissing2ref\fR +.RS 4 +sets missing genotypes ("\&./\&.") to ref allele ("0/0" or "0|0") +.RE +.PP +\fBsetGT\fR +.RS 4 +general tool to set genotypes according to rules requested by the user +.RE +.PP +\fBtag2tag\fR +.RS 4 +convert between similar tags, such as GL and GP +.RE +.PP +\fBtrio\-switch\-rate\fR +.RS 4 +calculate phase switch rate in trio samples, children samples must have phased GTs\&. +.RE +.RE +.sp +.it 1 an-trap +.nr an-no-space-flag 1 +.nr an-break-flag 1 +.br +.ps +1 +\fBExamples:\fR +.RS 4 +.sp +.if n \{\ +.RS 4 +.\} +.nf +# List options common to all plugins +bcftools plugin + +# List available plugins +bcftools plugin \-l + +# Run a plugin +bcftools plugin counts in\&.vcf + +# Run a plugin using the abbreviated "+" notation +bcftools +counts in\&.vcf + +# The input VCF can be streamed just like in other commands +cat in\&.vcf | bcftools +counts + +# Print usage information of plugin "dosage" +bcftools +dosage \-h + +# Replace missing genotypes with 0/0 +bcftools +missing2ref in\&.vcf + +# Replace missing genotypes with 0|0 +bcftools +missing2ref in\&.vcf \-\- \-p +.fi +.if n \{\ +.RE +.\} +.RE +.sp +.it 1 an-trap +.nr an-no-space-flag 1 +.nr an-break-flag 1 +.br +.ps +1 +\fBPlugins troubleshooting:\fR +.RS 4 +.sp +Things to check if your plugin does not show up in the \fBbcftools plugin \-l\fR output: +.sp +.RS 4 +.ie n \{\ +\h'-04'\(bu\h'+03'\c +.\} +.el \{\ +.sp -1 +.IP \(bu 2.3 +.\} +Run with the +\fB\-v\fR +option for verbose output: +\fBbcftools plugin \-lv\fR +.RE +.sp +.RS 4 +.ie n \{\ +\h'-04'\(bu\h'+03'\c +.\} +.el \{\ +.sp -1 +.IP \(bu 2.3 +.\} +Does the environment variable BCFTOOLS_PLUGINS include the correct path? +.RE +.RE +.sp +.it 1 an-trap +.nr an-no-space-flag 1 +.nr an-break-flag 1 +.br +.ps +1 +\fBPlugins API:\fR +.RS 4 +.sp +.if n \{\ +.RS 4 +.\} +.nf +// Short description used by \*(Aqbcftools plugin \-l\*(Aq +const char *about(void); + +// Longer description used by \*(Aqbcftools +name \-h\*(Aq +const char *usage(void); + +// Called once at startup, allows initialization of local variables\&. +// Return 1 to suppress normal VCF/BCF header output, \-1 on critical +// errors, 0 otherwise\&. +int init(int argc, char **argv, bcf_hdr_t *in_hdr, bcf_hdr_t *out_hdr); + +// Called for each VCF record, return NULL to suppress the output +bcf1_t *process(bcf1_t *rec); + +// Called after all lines have been processed to clean up +void destroy(void); +.fi +.if n \{\ +.RE +.\} +.RE +.SS "bcftools polysomy [\fIOPTIONS\fR] \fIfile\&.vcf\&.gz\fR" +.sp +Detect number of chromosomal copies in VCFs annotates with the Illumina\(cqs B\-allele frequency (BAF) values\&. Note that this command is not compiled in by default, see the section \fBOptional Compilation with GSL\fR in the INSTALL file for help\&. +.sp +.it 1 an-trap +.nr an-no-space-flag 1 +.nr an-break-flag 1 +.br +.ps +1 +\fBGeneral options:\fR +.RS 4 +.PP +\fB\-o, \-\-output\-dir\fR \fIpath\fR +.RS 4 +output directory +.RE +.PP +\fB\-r, \-\-regions\fR \fIchr\fR|\fIchr:pos\fR|\fIchr:from\-to\fR|\fIchr:from\-\fR[,\&...] +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-R, \-\-regions\-file\fR \fIfile\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-s, \-\-sample\fR \fIstring\fR +.RS 4 +sample name +.RE +.PP +\fB\-t, \-\-targets\fR \fILIST\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-T, \-\-targets\-file\fR \fIFILE\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-v, \-\-verbose\fR +.RS 4 +verbose debugging output which gives hints about the thresholds and decisions made by the program\&. Note that the exact output can change between versions\&. +.RE +.RE +.sp +.it 1 an-trap +.nr an-no-space-flag 1 +.nr an-break-flag 1 +.br +.ps +1 +\fBAlgorithm options:\fR +.RS 4 +.PP +\fB\-b, \-\-peak\-size\fR \fIfloat\fR +.RS 4 +the minimum peak size considered as a good match can be from the interval [0,1] where larger is stricter +.RE +.PP +\fB\-c, \-\-cn\-penalty\fR \fIfloat\fR +.RS 4 +a penalty for increasing copy number state\&. How this works: multiple peaks are always a better fit than a single peak, therefore the program prefers a single peak (normal copy number) unless the absolute deviation of the multiple peaks fit is significantly smaller\&. Here the meaning of "significant" is given by the +\fIfloat\fR +from the interval [0,1] where larger is stricter\&. +.RE +.PP +\fB\-f, \-\-fit\-th\fR \fIfloat\fR +.RS 4 +threshold for goodness of fit (normalized absolute deviation), smaller is stricter +.RE +.PP +\fB\-i, \-\-include\-aa\fR +.RS 4 +include also the AA peak in CN2 and CN3 evaluation\&. This usually requires increasing +\fB\-f\fR\&. +.RE +.PP +\fB\-m, \-\-min\-fraction\fR \fIfloat\fR +.RS 4 +minimum distinguishable fraction of aberrant cells\&. The experience shows that trustworthy are estimates of 20% and more\&. +.RE +.PP +\fB\-p, \-\-peak\-symmetry\fR \fIfloat\fR +.RS 4 +a heuristics to filter failed fits where the expected peak symmetry is violated\&. The +\fIfloat\fR +is from the interval [0,1] and larger is stricter +.RE +.RE +.SS "bcftools query [\fIOPTIONS\fR] \fIfile\&.vcf\&.gz\fR [\fIfile\&.vcf\&.gz\fR [\&...]]" +.sp +Extracts fields from VCF or BCF files and outputs them in user\-defined format\&. +.PP +\fB\-c, \-\-collapse\fR \fIsnps\fR|\fIindels\fR|\fIboth\fR|\fIall\fR|\fIsome\fR|\fInone\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-e, \-\-exclude\fR \fIEXPRESSION\fR +.RS 4 +exclude sites for which +\fIEXPRESSION\fR +is true\&. For valid expressions see +\fBEXPRESSIONS\fR\&. +.RE +.PP +\fB\-f, \-\-format\fR \fIFORMAT\fR +.RS 4 +learn by example, see below +.RE +.PP +\fB\-H, \-\-print\-header\fR +.RS 4 +print header +.RE +.PP +\fB\-i, \-\-include\fR \fIEXPRESSION\fR +.RS 4 +include only sites for which +\fIEXPRESSION\fR +is true\&. For valid expressions see +\fBEXPRESSIONS\fR\&. +.RE +.PP +\fB\-l, \-\-list\-samples\fR +.RS 4 +list sample names and exit +.RE +.PP +\fB\-o, \-\-output\fR \fIFILE\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-r, \-\-regions\fR \fIchr\fR|\fIchr:pos\fR|\fIchr:from\-to\fR|\fIchr:from\-\fR[,\&...] +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-R, \-\-regions\-file\fR \fIfile\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-s, \-\-samples\fR \fILIST\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-S, \-\-samples\-file\fR \fIFILE\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-t, \-\-targets\fR \fIchr\fR|\fIchr:pos\fR|\fIchr:from\-to\fR|\fIchr:from\-\fR[,\&...] +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-T, \-\-targets\-file\fR \fIfile\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-u, \-\-allow\-undef\-tags\fR +.RS 4 +do not throw an error if there are undefined tags in the format string, print "\&." instead +.RE +.PP +\fB\-v, \-\-vcf\-list\fR \fIFILE\fR +.RS 4 +process multiple VCFs listed in the file +.RE +.sp +.it 1 an-trap +.nr an-no-space-flag 1 +.nr an-break-flag 1 +.br +.ps +1 +\fBFormat:\fR +.RS 4 +.sp +.if n \{\ +.RS 4 +.\} +.nf +%CHROM The CHROM column (similarly also other columns: POS, ID, REF, ALT, QUAL, FILTER) +%INFO/TAG Any tag in the INFO column +%TYPE Variant type (REF, SNP, MNP, INDEL, BND, OTHER) +%MASK Indicates presence of the site in other files (with multiple files) +%TAG{INT} Curly brackets to subscript vectors (0\-based) +%FIRST_ALT Alias for %ALT{0} +[] Format fields must be enclosed in brackets to loop over all samples +%GT Genotype (e\&.g\&. 0/1) +%TBCSQ Translated FORMAT/BCSQ\&. See the csq command above for explanation and examples\&. +%TGT Translated genotype (e\&.g\&. C/A) +%IUPACGT Genotype translated to IUPAC ambiguity codes (e\&.g\&. M instead of C/A) +%LINE Prints the whole line +%SAMPLE Sample name +%POS0 POS in 0\-based coordinates +%END End position of the REF allele +%END0 End position of the REF allele in 0\-based cordinates +\en new line +\et tab character +.fi +.if n \{\ +.RE +.\} +.sp +.if n \{\ +.RS 4 +.\} +.nf +Everything else is printed verbatim\&. +.fi +.if n \{\ +.RE +.\} +.RE +.sp +.it 1 an-trap +.nr an-no-space-flag 1 +.nr an-break-flag 1 +.br +.ps +1 +\fBExamples:\fR +.RS 4 +.sp +.if n \{\ +.RS 4 +.\} +.nf +# Print chromosome, position, ref allele and the first alternate allele +bcftools query \-f \*(Aq%CHROM %POS %REF %ALT{0}\en\*(Aq file\&.vcf\&.gz +.fi +.if n \{\ +.RE +.\} +.sp +.if n \{\ +.RS 4 +.\} +.nf +# Similar to above, but use tabs instead of spaces, add sample name and genotype +bcftools query \-f \*(Aq%CHROM\et%POS\et%REF\et%ALT[\et%SAMPLE=%GT]\en\*(Aq file\&.vcf\&.gz +.fi +.if n \{\ +.RE +.\} +.sp +.if n \{\ +.RS 4 +.\} +.nf +# Print FORMAT/GT fields followed by FORMAT/GT fields +bcftools query \-f \*(AqGQ:[ %GQ] \et GT:[ %GT]\en\*(Aq file\&.vcf +.fi +.if n \{\ +.RE +.\} +.sp +.if n \{\ +.RS 4 +.\} +.nf +# Make a BED file: chr, pos (0\-based), end pos (1\-based), id +bcftools query \-f\*(Aq%CHROM\et%POS0\et%END\et%ID\en\*(Aq file\&.bcf +.fi +.if n \{\ +.RE +.\} +.RE +.SS "bcftools reheader [\fIOPTIONS\fR] \fIfile\&.vcf\&.gz\fR" +.sp +Modify header of VCF/BCF files, change sample names\&. +.PP +\fB\-h, \-\-header\fR \fIFILE\fR +.RS 4 +new VCF header +.RE +.PP +\fB\-o, \-\-output\fR \fIFILE\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-s, \-\-samples\fR \fIFILE\fR +.RS 4 +new sample names, one name per line, in the same order as they appear in the VCF file\&. Alternatively, only samples which need to be renamed can be listed as "old_name new_name\en" pairs separated by whitespaces, each on a separate line\&. If a sample name contains spaces, the spaces can be escaped using the backslash character, for example "Not\e a\e good\e sample\e name"\&. +.RE +.SS "bcftools roh [\fIOPTIONS\fR] \fIfile\&.vcf\&.gz\fR" +.sp +A program for detecting runs of homo/autozygosity\&. Only bi\-allelic sites are considered\&. +.sp +.it 1 an-trap +.nr an-no-space-flag 1 +.nr an-break-flag 1 +.br +.ps +1 +\fBThe HMM model:\fR +.RS 4 +.sp +.if n \{\ +.RS 4 +.\} +.nf +Notation: + D = Data, AZ = autozygosity, HW = Hardy\-Weinberg (non\-autozygosity), + f = non\-ref allele frequency + +Emission probabilities: + oAZ = P_i(D|AZ) = (1\-f)*P(D|RR) + f*P(D|AA) + oHW = P_i(D|HW) = (1\-f)^2 * P(D|RR) + f^2 * P(D|AA) + 2*f*(1\-f)*P(D|RA) + +Transition probabilities: + tAZ = P(AZ|HW) \&.\&. from HW to AZ, the \-a parameter + tHW = P(HW|AZ) \&.\&. from AZ to HW, the \-H parameter + + ci = P_i(C) \&.\&. probability of cross\-over at site i, from genetic map + AZi = P_i(AZ) \&.\&. probability of site i being AZ/non\-AZ, scaled so that AZi+HWi = 1 + HWi = P_i(HW) + + P_{i+1}(AZ) = oAZ * max[(1 \- tAZ * ci) * AZ{i\-1} , tAZ * ci * (1\-AZ{i\-1})] + P_{i+1}(HW) = oHW * max[(1 \- tHW * ci) * (1\-AZ{i\-1}) , tHW * ci * AZ{i\-1}] +.fi +.if n \{\ +.RE +.\} +.RE +.sp +.it 1 an-trap +.nr an-no-space-flag 1 +.nr an-break-flag 1 +.br +.ps +1 +\fBGeneral Options:\fR +.RS 4 +.PP +\fB\-\-AF\-dflt\fR \fIFLOAT\fR +.RS 4 +in case allele frequency is not known, use the +\fIFLOAT\fR\&. By default, sites where allele frequency cannot be determined, or is 0, are skipped\&. +.RE +.PP +\fB\-\-AF\-tag\fR \fITAG\fR +.RS 4 +use the specified INFO tag +\fITAG\fR +as an allele frequency estimate instead of the default AC and AN tags\&. Sites which do not have +\fITAG\fR +will be skipped\&. +.RE +.PP +\fB\-\-AF\-file\fR \fIFILE\fR +.RS 4 +Read allele frequencies from a tab\-delimited file containing the columns: CHROM\etPOS\etREF,ALT\etAF\&. The file can be compressed with +\fBbgzip\fR +and indexed with tabix \-s1 \-b2 \-e2\&. Sites which are not present in the +\fIFILE\fR +or have different reference or alternate allele will be skipped\&. Note that such a file can be easily created from a VCF using: +.RE +.sp +.if n \{\ +.RS 4 +.\} +.nf + bcftools query \-f\*(Aq%CHROM\et%POS\et%REF,%ALT\et%INFO/TAG\en\*(Aq file\&.vcf | bgzip \-c > freqs\&.tab\&.gz +.fi +.if n \{\ +.RE +.\} +.PP +\fB\-b, \-\-buffer\-size\fR \fIINT\fR[,\fIINT\fR] +.RS 4 +when the entire many\-sample file cannot fit into memory, a sliding buffer approach can be used\&. The first value is the number of sites to keep in memory\&. If negative, it is interpreted as the maximum memory to use, in MB\&. The second, optional, value sets the number of overlapping sites\&. The default overlap is set to roughly 1% of the buffer size\&. +.RE +.PP +\fB\-e, \-\-estimate\-AF\fR \fIFILE\fR +.RS 4 +estimate the allele frequency by recalculating INFO/AC and INFO/AN on the fly, using the specified +\fITAG\fR +which can be either FORMAT/GT ("GT") or FORMAT/PL ("PL")\&. If +\fITAG\fR +is not given, "GT" is assumed\&. Either all samples ("\-") or samples listed in +\fIFILE\fR +will be included\&. For example, use "PL,\-" to estimate AF from FORMAT/PL of all samples\&. If neither +\fB\-e\fR +nor the other +\fB\-\-AF\-\&...\fR +options are given, the allele frequency is estimated from AC and AN counts which are already present in the INFO field\&. +.RE +.PP +\fB\-G, \-\-GTs\-only\fR \fIFLOAT\fR +.RS 4 +use genotypes (FORMAT/GT fields) ignoring genotype likelihoods (FORMAT/PL), setting PL of unseen genotypes to +\fIFLOAT\fR\&. Safe value to use is 30 to account for GT errors\&. +.RE +.PP +\fB\-I, \-\-skip\-indels\fR +.RS 4 +skip indels as their genotypes are usually enriched for errors +.RE +.PP +\fB\-m, \-\-genetic\-map\fR \fIFILE\fR +.RS 4 +genetic map in the format required also by IMPUTE2\&. Only the first and third column are used (position and Genetic_Map(cM))\&. The +\fIFILE\fR +can chromosome name\&. +.RE +.PP +\fB\-M, \-\-rec\-rate\fR \fIFLOAT\fR +.RS 4 +constant recombination rate per bp\&. In combination with +\fB\-\-genetic\-map\fR, the +\fB\-\-rec\-rate\fR +parameter is interpreted differently, as +\fIFLOAT\fR\-fold increase of transition probabilities, which allows the model to become more sensitive yet still account for recombination hotspots\&. Note that also the range of the values is therefore different in both cases: normally the parameter will be in the range (1e\-3,1e\-9) but with +\fB\-\-genetic\-map\fR +it will be in the range (10,1000)\&. +.RE +.PP +\fB\-o, \-\-output\fR \fIFILE\fR +.RS 4 +Write output to the +\fIFILE\fR, by default the output is printed on stdout +.RE +.PP +\fB\-O, \-\-output\-type\fR \fIs\fR|\fIr\fR[\fIz\fR] +.RS 4 +Generate per\-site output (\fIs\fR) or per\-region output (\fIr\fR)\&. By default both types are printed and the output is uncompressed\&. Add +\fIz\fR +for a compressed output\&. +.RE +.PP +\fB\-r, \-\-regions\fR \fIchr\fR|\fIchr:pos\fR|\fIchr:from\-to\fR|\fIchr:from\-\fR[,\&...] +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-R, \-\-regions\-file\fR \fIfile\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-s, \-\-samples\fR \fILIST\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-S, \-\-samples\-file\fR \fIFILE\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-t, \-\-targets\fR \fIchr\fR|\fIchr:pos\fR|\fIchr:from\-to\fR|\fIchr:from\-\fR[,\&...] +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-T, \-\-targets\-file\fR \fIfile\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.RE +.sp +.it 1 an-trap +.nr an-no-space-flag 1 +.nr an-break-flag 1 +.br +.ps +1 +\fBHMM Options:\fR +.RS 4 +.PP +\fB\-a, \-\-hw\-to\-az\fR \fIFLOAT\fR +.RS 4 +P(AZ|HW) transition probability from AZ (autozygous) to HW (Hardy\-Weinberg) state +.RE +.PP +\fB\-H, \-\-az\-to\-hw\fR \fIFLOAT\fR +.RS 4 +P(HW|AZ) transition probability from HW to AZ state +.RE +.PP +\fB\-V, \-\-viterbi\-training\fR \fIFLOAT\fR +.RS 4 +estimate HMM parameters using Baum\-Welch algorithm, using the convergence threshold +\fIFLOAT\fR, e\&.g\&. 1e\-10 (experimental) +.RE +.RE +.SS "bcftools stats [\fIOPTIONS\fR] \fIA\&.vcf\&.gz\fR [\fIB\&.vcf\&.gz\fR]" +.sp +Parses VCF or BCF and produces text file stats which is suitable for machine processing and can be plotted using \fBplot\-vcfstats\fR\&. When two files are given, the program generates separate stats for intersection and the complements\&. By default only sites are compared, \fB\-s\fR/\fB\-S\fR must given to include also sample columns\&. When one VCF file is specified on the command line, then stats by non\-reference allele frequency, depth distribution, stats by quality and per\-sample counts, singleton stats, etc\&. are printed\&. When two VCF files are given, then stats such as concordance (Genotype concordance by non\-reference allele frequency, Genotype concordance by sample, Non\-Reference Discordance) and correlation are also printed\&. Per\-site discordance (PSD) is also printed in \fB\-\-verbose\fR mode\&. +.PP +\fB\-\-af\-bins\fR \fILIST\fR|\fIFILE\fR +.RS 4 +comma separated list of allele frequency bins (e\&.g\&. 0\&.1,0\&.5,1) or a file listing the allele frequency bins one per line (e\&.g\&. 0\&.1\en0\&.5\en1) +.RE +.PP +\fB\-\-af\-tag\fR \fITAG\fR +.RS 4 +allele frequency INFO tag to use for binning\&. By default the allele frequency is estimated from AC/AN, if available, or directly from the genotypes (GT) if not\&. +.RE +.PP +\fB\-1, \-\-1st\-allele\-only\fR +.RS 4 +consider only the 1st alternate allele at multiallelic sites +.RE +.PP +\fB\-c, \-\-collapse\fR \fIsnps\fR|\fIindels\fR|\fIboth\fR|\fIall\fR|\fIsome\fR|\fInone\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-d, \-\-depth\fR \fIINT\fR,\fIINT\fR,\fIINT\fR +.RS 4 +ranges of depth distribution: min, max, and size of the bin +.RE +.PP +\fB\-\-debug\fR +.RS 4 +produce verbose per\-site and per\-sample output +.RE +.PP +\fB\-e, \-\-exclude\fR \fIEXPRESSION\fR +.RS 4 +exclude sites for which +\fIEXPRESSION\fR +is true\&. For valid expressions see +\fBEXPRESSIONS\fR\&. +.RE +.PP +\fB\-E, \-\-exons\fR \fIfile\&.gz\fR +.RS 4 +tab\-delimited file with exons for indel frameshifts statistics\&. The columns of the file are CHR, FROM, TO, with 1\-based, inclusive, positions\&. The file is BGZF\-compressed and indexed with tabix +.RE +.sp +.if n \{\ +.RS 4 +.\} +.nf + tabix \-s1 \-b2 \-e3 file\&.gz +.fi +.if n \{\ +.RE +.\} +.PP +\fB\-f, \-\-apply\-filters\fR \fILIST\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-F, \-\-fasta\-ref\fR \fIref\&.fa\fR +.RS 4 +faidx indexed reference sequence file to determine INDEL context +.RE +.PP +\fB\-i, \-\-include\fR \fIEXPRESSION\fR +.RS 4 +include only sites for which +\fIEXPRESSION\fR +is true\&. For valid expressions see +\fBEXPRESSIONS\fR\&. +.RE +.PP +\fB\-I, \-\-split\-by\-ID\fR +.RS 4 +collect stats separately for sites which have the ID column set ("known sites") or which do not have the ID column set ("novel sites")\&. +.RE +.PP +\fB\-r, \-\-regions\fR \fIchr\fR|\fIchr:pos\fR|\fIchr:from\-to\fR|\fIchr:from\-\fR[,\&...] +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-R, \-\-regions\-file\fR \fIfile\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-s, \-\-samples\fR \fILIST\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-S, \-\-samples\-file\fR \fIFILE\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-t, \-\-targets\fR \fIchr\fR|\fIchr:pos\fR|\fIchr:from\-to\fR|\fIchr:from\-\fR[,\&...] +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-T, \-\-targets\-file\fR \fIfile\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-u, \-\-user\-tstv\fR \fI\fR +.RS 4 +collect Ts/Tv stats for any tag using the given binning [0:1:100] +.RE +.PP +\fB\-v, \-\-verbose\fR +.RS 4 +produce verbose per\-site and per\-sample output +.RE +.SS "bcftools view [\fIOPTIONS\fR] \fIfile\&.vcf\&.gz\fR [\fIREGION\fR [\&...]]" +.sp +View, subset and filter VCF or BCF files by position and filtering expression\&. Convert between VCF and BCF\&. Former \fBbcftools subset\fR\&. +.sp +.it 1 an-trap +.nr an-no-space-flag 1 +.nr an-break-flag 1 +.br +.ps +1 +\fBOutput options\fR +.RS 4 +.PP +\fB\-G, \-\-drop\-genotypes\fR +.RS 4 +drop individual genotype information (after subsetting if +\fB\-s\fR +option is set) +.RE +.PP +\fB\-h, \-\-header\-only\fR +.RS 4 +output the VCF header only +.RE +.PP +\fB\-H, \-\-no\-header\fR +.RS 4 +suppress the header in VCF output +.RE +.PP +\fB\-l, \-\-compression\-level\fR [\fI0\-9\fR] +.RS 4 +compression level\&. 0 stands for uncompressed, 1 for best speed and 9 for best compression\&. +.RE +.PP +\fB\-\-no\-version\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-O, \-\-output\-type\fR \fIb\fR|\fIu\fR|\fIz\fR|\fIv\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.sp +\fB\-o, \-\-output\-file\fR \fIFILE\fR: output file name\&. If not present, the default is to print to standard output (stdout)\&. +.PP +\fB\-r, \-\-regions\fR \fIchr\fR|\fIchr:pos\fR|\fIchr:from\-to\fR|\fIchr:from\-\fR[,\&...] +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-R, \-\-regions\-file\fR \fIfile\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-t, \-\-targets\fR \fIchr\fR|\fIchr:pos\fR|\fIchr:from\-to\fR|\fIchr:from\-\fR[,\&...] +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-T, \-\-targets\-file\fR \fIfile\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-\-threads\fR \fIINT\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.RE +.sp +.it 1 an-trap +.nr an-no-space-flag 1 +.nr an-break-flag 1 +.br +.ps +1 +\fBSubset options:\fR +.RS 4 +.PP +\fB\-a, \-\-trim\-alt\-alleles\fR +.RS 4 +trim alternate alleles not seen in subset\&. Type A, G and R INFO and FORMAT fields will also be trimmed +.RE +.PP +\fB\-\-force\-samples\fR +.RS 4 +only warn about unknown subset samples +.RE +.PP +\fB\-I, \-\-no\-update\fR +.RS 4 +do not (re)calculate INFO fields for the subset (currently INFO/AC and INFO/AN) +.RE +.PP +\fB\-s, \-\-samples\fR \fILIST\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-S, \-\-samples\-file\fR \fIFILE\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.RE +.sp +.it 1 an-trap +.nr an-no-space-flag 1 +.nr an-break-flag 1 +.br +.ps +1 +\fBFilter options:\fR +.RS 4 +.sp +Note that filter options below dealing with counting the number of alleles will, for speed, first check for the values of AC and AN in the INFO column to avoid parsing all the genotype (FORMAT/GT) fields in the VCF\&. This means that a filter like \fI\-\-min\-af 0\&.1\fR will be based \(oqAC/AN\(cq where AC and AN come from either INFO/AC and INFO/AN if available or FORMAT/GT if not\&. It will not filter on another field like INFO/AF\&. The \fI\-\-include\fR and \fI\-\-exclude\fR filter expressions should instead be used to explicitly filter based on fields in the INFO column, e\&.g\&. \fI\-\-exclude AF<0\&.1\fR\&. +.PP +\fB\-c, \-\-min\-ac\fR \fIINT\fR[\fI:nref\fR|\fI:alt1\fR|\fI:minor\fR|\fI:major\fR|:\*(Aqnonmajor\*(Aq] +.RS 4 +minimum allele count (INFO/AC) of sites to be printed\&. Specifying the type of allele is optional and can be set to non\-reference (\fInref\fR, the default), 1st alternate (\fIalt1\fR), the least frequent (\fIminor\fR), the most frequent (\fImajor\fR) or sum of all but the most frequent (\fInonmajor\fR) alleles\&. +.RE +.PP +\fB\-C, \-\-max\-ac\fR \fIINT\fR[\fI:nref\fR|\fI:alt1\fR|\fI:minor\fR|:\*(Aqmajor\*(Aq|:\*(Aqnonmajor\*(Aq] +.RS 4 +maximum allele count (INFO/AC) of sites to be printed\&. Specifying the type of allele is optional and can be set to non\-reference (\fInref\fR, the default), 1st alternate (\fIalt1\fR), the least frequent (\fIminor\fR), the most frequent (\fImajor\fR) or sum of all but the most frequent (\fInonmajor\fR) alleles\&. +.RE +.PP +\fB\-e, \-\-exclude\fR \fIEXPRESSION\fR +.RS 4 +exclude sites for which +\fIEXPRESSION\fR +is true\&. For valid expressions see +\fBEXPRESSIONS\fR\&. +.RE +.PP +\fB\-f, \-\-apply\-filters\fR \fILIST\fR +.RS 4 +see +\fBCommon Options\fR +.RE +.PP +\fB\-g, \-\-genotype\fR [^][\fIhom\fR|\fIhet\fR|\fImiss\fR] +.RS 4 +include only sites with one or more homozygous (\fIhom\fR), heterozygous (\fIhet\fR) or missing (\fImiss\fR) genotypes\&. When prefixed with +\fI^\fR, the logic is reversed; thus +\fI^het\fR +excludes sites with heterozygous genotypes\&. +.RE +.PP +\fB\-i, \-\-include\fR \fIEXPRESSION\fR +.RS 4 +include sites for which +\fIEXPRESSION\fR +is true\&. For valid expressions see +\fBEXPRESSIONS\fR\&. +.RE +.PP +\fB\-k, \-\-known\fR +.RS 4 +print known sites only (ID column is not "\&.") +.RE +.PP +\fB\-m, \-\-min\-alleles\fR \fIINT\fR +.RS 4 +print sites with at least +\fIINT\fR +alleles listed in REF and ALT columns +.RE +.PP +\fB\-M, \-\-max\-alleles\fR \fIINT\fR +.RS 4 +print sites with at most +\fIINT\fR +alleles listed in REF and ALT columns\&. Use +\fB\-m2 \-M2 \-v snps\fR +to only view biallelic SNPs\&. +.RE +.PP +\fB\-n, \-\-novel\fR +.RS 4 +print novel sites only (ID column is "\&.") +.RE +.PP +\fB\-p, \-\-phased\fR +.RS 4 +print sites where all samples are phased\&. Haploid genotypes are considered phased\&. Missing genotypes considered unphased unless the phased bit is set\&. +.RE +.PP +\fB\-P, \-\-exclude\-phased\fR +.RS 4 +exclude sites where all samples are phased +.RE +.PP +\fB\-q, \-\-min\-af\fR \fIFLOAT\fR[\fI:nref\fR|\fI:alt1\fR|\fI:minor\fR|\fI:major\fR|\fI:nonmajor\fR] +.RS 4 +minimum allele frequency (INFO/AC / INFO/AN) of sites to be printed\&. Specifying the type of allele is optional and can be set to non\-reference (\fInref\fR, the default), 1st alternate (\fIalt1\fR), the least frequent (\fIminor\fR), the most frequent (\fImajor\fR) or sum of all but the most frequent (\fInonmajor\fR) alleles\&. +.RE +.PP +\fB\-Q, \-\-max\-af\fR \fIFLOAT\fR[\fI:nref\fR|\fI:alt1\fR|\fI:minor\fR|\fI:major\fR|\fI:nonmajor\fR] +.RS 4 +maximum allele frequency (INFO/AC / INFO/AN) of sites to be printed\&. Specifying the type of allele is optional and can be set to non\-reference (\fInref\fR, the default), 1st alternate (\fIalt1\fR), the least frequent (\fIminor\fR), the most frequent (\fImajor\fR) or sum of all but the most frequent (\fInonmajor\fR) alleles\&. +.RE +.PP +\fB\-u, \-\-uncalled\fR +.RS 4 +print sites without a called genotype +.RE +.PP +\fB\-U, \-\-exclude\-uncalled\fR +.RS 4 +exclude sites without a called genotype +.RE +.PP +\fB\-v, \-\-types\fR \fIsnps\fR|\fIindels\fR|\fImnps\fR|\fIother\fR +.RS 4 +comma\-separated list of variant types to select\&. Site is selected if any of the ALT alleles is of the type requested\&. Types are determined by comparing the REF and ALT alleles in the VCF record not INFO tags like INFO/INDEL or INFO/VT\&. Use +\fB\-\-include\fR +to select based on INFO tags\&. +.RE +.PP +\fB\-V, \-\-exclude\-types\fR \fIsnps\fR|\fIindels\fR|\fImnps\fR|\fIref\fR|\fIbnd\fR|\fIother\fR +.RS 4 +comma\-separated list of variant types to exclude\&. Site is excluded if any of the ALT alleles is of the type requested\&. Types are determined by comparing the REF and ALT alleles in the VCF record not INFO tags like INFO/INDEL or INFO/VT\&. Use +\fB\-\-exclude\fR +to exclude based on INFO tags\&. +.RE +.PP +\fB\-x, \-\-private\fR +.RS 4 +print sites where only the subset samples carry an non\-reference allele\&. Requires +\fB\-\-samples\fR +or +\fB\-\-samples\-file\fR\&. +.RE +.PP +\fB\-X, \-\-exclude\-private\fR +.RS 4 +exclude sites where only the subset samples carry an non\-reference allele +.RE +.RE +.SS "bcftools help [\fICOMMAND\fR] | bcftools \-\-help [\fICOMMAND\fR]" +.sp +Display a brief usage message listing the bcftools commands available\&. If the name of a command is also given, e\&.g\&., bcftools help view, the detailed usage message for that particular command is displayed\&. +.SS "bcftools [\fI\-\-version\fR|\fI\-v\fR]" +.sp +Display the version numbers and copyright information for bcftools and the important libraries used by bcftools\&. +.SS "bcftools [\fI\-\-version\-only\fR]" +.sp +Display the full bcftools version number in a machine\-readable format\&. +.SH "EXPRESSIONS" +.sp +These filtering expressions are accepted by most of the commands\&. +.PP +\fBValid expressions may contain:\fR +.sp +.RS 4 +.ie n \{\ +\h'-04'\(bu\h'+03'\c +.\} +.el \{\ +.sp -1 +.IP \(bu 2.3 +.\} +numerical constants, string constants, file names +.sp +.if n \{\ +.RS 4 +.\} +.nf +1, 1\&.0, 1e\-4 +"String" +@file_name +.fi +.if n \{\ +.RE +.\} +.RE +.sp +.RS 4 +.ie n \{\ +\h'-04'\(bu\h'+03'\c +.\} +.el \{\ +.sp -1 +.IP \(bu 2.3 +.\} +arithmetic operators +.sp +.if n \{\ +.RS 4 +.\} +.nf ++,*,\-,/ +.fi +.if n \{\ +.RE +.\} +.RE +.sp +.RS 4 +.ie n \{\ +\h'-04'\(bu\h'+03'\c +.\} +.el \{\ +.sp -1 +.IP \(bu 2.3 +.\} +comparison operators +.sp +.if n \{\ +.RS 4 +.\} +.nf +== (same as =), >, >=, <=, <, != +.fi +.if n \{\ +.RE +.\} +.RE +.sp +.RS 4 +.ie n \{\ +\h'-04'\(bu\h'+03'\c +.\} +.el \{\ +.sp -1 +.IP \(bu 2.3 +.\} +regex operators "~" and its negation "!~"\&. The expressions are case sensitive unless "/i" is added\&. +.sp +.if n \{\ +.RS 4 +.\} +.nf +INFO/HAYSTACK ~ "needle" +INFO/HAYSTACK ~ "NEEDless/i" +.fi +.if n \{\ +.RE +.\} +.RE +.sp +.RS 4 +.ie n \{\ +\h'-04'\(bu\h'+03'\c +.\} +.el \{\ +.sp -1 +.IP \(bu 2.3 +.\} +parentheses +.sp +.if n \{\ +.RS 4 +.\} +.nf +(, ) +.fi +.if n \{\ +.RE +.\} +.RE +.sp +.RS 4 +.ie n \{\ +\h'-04'\(bu\h'+03'\c +.\} +.el \{\ +.sp -1 +.IP \(bu 2.3 +.\} +logical operators +.sp +.if n \{\ +.RS 4 +.\} +.nf +&& (same as &), ||, | +.fi +.if n \{\ +.RE +.\} +.RE +.sp +.RS 4 +.ie n \{\ +\h'-04'\(bu\h'+03'\c +.\} +.el \{\ +.sp -1 +.IP \(bu 2.3 +.\} +INFO tags, FORMAT tags, column names +.sp +.if n \{\ +.RS 4 +.\} +.nf +INFO/DP or DP +FORMAT/DV, FMT/DV, or DV +FILTER, QUAL, ID, POS, REF, ALT[0] +.fi +.if n \{\ +.RE +.\} +.RE +.sp +.RS 4 +.ie n \{\ +\h'-04'\(bu\h'+03'\c +.\} +.el \{\ +.sp -1 +.IP \(bu 2.3 +.\} +1 (or 0) to test the presence (or absence) of a flag +.sp +.if n \{\ +.RS 4 +.\} +.nf +FlagA=1 && FlagB=0 +.fi +.if n \{\ +.RE +.\} +.RE +.sp +.RS 4 +.ie n \{\ +\h'-04'\(bu\h'+03'\c +.\} +.el \{\ +.sp -1 +.IP \(bu 2.3 +.\} +"\&." to test missing values +.sp +.if n \{\ +.RS 4 +.\} +.nf +DP="\&.", DP!="\&.", ALT="\&." +.fi +.if n \{\ +.RE +.\} +.RE +.sp +.RS 4 +.ie n \{\ +\h'-04'\(bu\h'+03'\c +.\} +.el \{\ +.sp -1 +.IP \(bu 2.3 +.\} +missing genotypes can be matched regardless of phase and ploidy ("\&.|\&.", "\&./\&.", "\&.") using these expressions +.sp +.if n \{\ +.RS 4 +.\} +.nf +GT~"\e\&.", GT!~"\e\&." +.fi +.if n \{\ +.RE +.\} +.RE +.sp +.RS 4 +.ie n \{\ +\h'-04'\(bu\h'+03'\c +.\} +.el \{\ +.sp -1 +.IP \(bu 2.3 +.\} +missing genotypes can be matched including the phase and ploidy ("\&.|\&.", "\&./\&.", "\&.") using these expressions +.sp +.if n \{\ +.RS 4 +.\} +.nf +GT="\&.|\&.", GT="\&./\&.", GT="\&." +.fi +.if n \{\ +.RE +.\} +.RE +.sp +.RS 4 +.ie n \{\ +\h'-04'\(bu\h'+03'\c +.\} +.el \{\ +.sp -1 +.IP \(bu 2.3 +.\} +TYPE for variant type in REF,ALT columns (indel,snp,mnp,ref,bnd,other)\&. Use the regex operator "\e~" to require at least one allele of the given type or the equal sign "=" to require that all alleles are of the given type\&. Compare +.sp +.if n \{\ +.RS 4 +.\} +.nf +TYPE="snp" +TYPE~"snp" +TYPE!="snp" +TYPE!~"snp" +.fi +.if n \{\ +.RE +.\} +.RE +.sp +.RS 4 +.ie n \{\ +\h'-04'\(bu\h'+03'\c +.\} +.el \{\ +.sp -1 +.IP \(bu 2.3 +.\} +array subscripts, "*" for any field +.sp +.if n \{\ +.RS 4 +.\} +.nf +(DP4[0]+DP4[1])/(DP4[2]+DP4[3]) > 0\&.3 +DP4[*] == 0 +CSQ[*] ~ "missense_variant\&.*deleterious" +.fi +.if n \{\ +.RE +.\} +.RE +.sp +.RS 4 +.ie n \{\ +\h'-04'\(bu\h'+03'\c +.\} +.el \{\ +.sp -1 +.IP \(bu 2.3 +.\} +function on FORMAT tags (over samples) and INFO tags (over vector fields) +.sp +.if n \{\ +.RS 4 +.\} +.nf +MAX, MIN, AVG, SUM, STRLEN, ABS +.fi +.if n \{\ +.RE +.\} +.RE +.sp +.RS 4 +.ie n \{\ +\h'-04'\(bu\h'+03'\c +.\} +.el \{\ +.sp -1 +.IP \(bu 2.3 +.\} +variables calculated on the fly if not present: number of alternate alleles; number of samples; count of alternate alleles; minor allele count (similar to AC but is always smaller than 0\&.5); frequency of alternate alleles (AF=AC/AN); frequency of minor alleles (MAF=MAC/AN); number of alleles in called genotypes +.sp +.if n \{\ +.RS 4 +.\} +.nf +N_ALT, N_SAMPLES, AC, MAC, AF, MAF, AN +.fi +.if n \{\ +.RE +.\} +.RE +.PP +\fBNotes:\fR +.sp +.RS 4 +.ie n \{\ +\h'-04'\(bu\h'+03'\c +.\} +.el \{\ +.sp -1 +.IP \(bu 2.3 +.\} +String comparisons and regular expressions are case\-insensitive +.RE +.sp +.RS 4 +.ie n \{\ +\h'-04'\(bu\h'+03'\c +.\} +.el \{\ +.sp -1 +.IP \(bu 2.3 +.\} +If the subscript "*" is used in regular expression search, the whole field is treated as one string\&. For example, the regex STR[*]~"B,C" will be true for the string vector INFO/STR=AB,CD\&. +.RE +.sp +.RS 4 +.ie n \{\ +\h'-04'\(bu\h'+03'\c +.\} +.el \{\ +.sp -1 +.IP \(bu 2.3 +.\} +Variables and function names are case\-insensitive, but not tag names\&. For example, "qual" can be used instead of "QUAL", "strlen()" instead of "STRLEN()" , but not "dp" instead of "DP"\&. +.RE +.sp +\fBExamples:\fR +.sp +.if n \{\ +.RS 4 +.\} +.nf +MIN(DV)>5 +.fi +.if n \{\ +.RE +.\} +.sp +.if n \{\ +.RS 4 +.\} +.nf +MIN(DV/DP)>0\&.3 +.fi +.if n \{\ +.RE +.\} +.sp +.if n \{\ +.RS 4 +.\} +.nf +MIN(DP)>10 & MIN(DV)>3 +.fi +.if n \{\ +.RE +.\} +.sp +.if n \{\ +.RS 4 +.\} +.nf +FMT/DP>10 & FMT/GQ>10 \&.\&. both conditions must be satisfied within one sample +.fi +.if n \{\ +.RE +.\} +.sp +.if n \{\ +.RS 4 +.\} +.nf +FMT/DP>10 && FMT/GQ>10 \&.\&. the conditions can be satisfied in different samples +.fi +.if n \{\ +.RE +.\} +.sp +.if n \{\ +.RS 4 +.\} +.nf +QUAL>10 | FMT/GQ>10 \&.\&. selects only GQ>10 samples +.fi +.if n \{\ +.RE +.\} +.sp +.if n \{\ +.RS 4 +.\} +.nf +QUAL>10 || FMT/GQ>10 \&.\&. selects all samples at QUAL>10 sites +.fi +.if n \{\ +.RE +.\} +.sp +.if n \{\ +.RS 4 +.\} +.nf +TYPE="snp" && QUAL>=10 && (DP4[2]+DP4[3] > 2) +.fi +.if n \{\ +.RE +.\} +.sp +.if n \{\ +.RS 4 +.\} +.nf +MIN(DP)>35 && AVG(GQ)>50 +.fi +.if n \{\ +.RE +.\} +.sp +.if n \{\ +.RS 4 +.\} +.nf +ID=@file \&.\&. selects lines with ID present in the file +.fi +.if n \{\ +.RE +.\} +.sp +.if n \{\ +.RS 4 +.\} +.nf +ID!=@~/file \&.\&. skip lines with ID present in the ~/file +.fi +.if n \{\ +.RE +.\} +.sp +.if n \{\ +.RS 4 +.\} +.nf +MAF[0]<0\&.05 \&.\&. select rare variants at 5% cutoff +.fi +.if n \{\ +.RE +.\} +.sp +.if n \{\ +.RS 4 +.\} +.nf +POS>=100 \&.\&. restrict your range query, e\&.g\&. 20:100\-200 to strictly sites with POS in that range\&. +.fi +.if n \{\ +.RE +.\} +.sp +\fBShell expansion:\fR +.sp +Note that expressions must often be quoted because some characters have special meaning in the shell\&. An example of expression enclosed in single quotes which cause that the whole expression is passed to the program as intended: +.sp +.if n \{\ +.RS 4 +.\} +.nf +bcftools view \-i \*(Aq%ID!="\&." & MAF[0]<0\&.01\*(Aq +.fi +.if n \{\ +.RE +.\} +.sp +Please refer to the documentation of your shell for details\&. +.SH "SCRIPTS AND OPTIONS" +.SS "plot\-vcfstats [\fIOPTIONS\fR] \fIfile\&.vchk\fR [\&...]" +.sp +Script for processing output of \fBbcftools stats\fR\&. It can merge results from multiple outputs (useful when running the stats for each chromosome separately), plots graphs and creates a PDF presentation\&. +.PP +\fB\-m, \-\-merge\fR +.RS 4 +Merge vcfstats files to STDOUT, skip plotting\&. +.RE +.PP +\fB\-p, \-\-prefix\fR \fIDIR\fR +.RS 4 +The output directory\&. This directory will be created if it does not exist\&. +.RE +.PP +\fB\-P, \-\-no\-PDF\fR +.RS 4 +Skip the PDF creation step\&. +.RE +.PP +\fB\-r, \-\-rasterize\fR +.RS 4 +Rasterize PDF images for faster rendering\&. +.RE +.PP +\fB\-s, \-\-sample\-names\fR +.RS 4 +Use sample names for xticks rather than numeric IDs\&. +.RE +.PP +\fB\-t, \-\-title\fR \fISTRING\fR +.RS 4 +Identify files by these titles in plots\&. The option can be given multiple times, for each ID in the +\fBbcftools stats\fR +output\&. If not present, the script will use abbreviated source file names for the titles\&. +.RE +.PP +\fB\-T, \-\-main\-title\fR \fISTRING\fR +.RS 4 +Main title for the PDF\&. +.RE +.SH "PERFORMANCE" +.sp +HTSlib was designed with BCF format in mind\&. When parsing VCF files, all records are internally converted into BCF representation\&. Simple operations, like removing a single column from a VCF file, can be therefore done much faster with standard UNIX commands, such as \fBawk\fR or \fBcut\fR\&. Therefore it is recommended to use BCF as input/output format whenever possible to avoid large overhead of the VCF → BCF → VCF conversion\&. +.SH "BUGS" +.sp +Please report any bugs you encounter on the github website: http://github\&.com/samtools/bcftools +.SH "AUTHORS" +.sp +Heng Li from the Sanger Institute wrote the original C version of htslib, samtools and bcftools\&. Bob Handsaker from the Broad Institute implemented the BGZF library\&. Petr Danecek, Shane McCarthy and John Marshall are maintaining and further developing bcftools\&. Many other people contributed to the program and to the file format specifications, both directly and indirectly by providing patches, testing and reporting bugs\&. We thank them all\&. +.SH "RESOURCES" +.sp +BCFtools GitHub website: http://github\&.com/samtools/bcftools +.sp +Samtools GitHub website: http://github\&.com/samtools/samtools +.sp +HTSlib GitHub website: http://github\&.com/samtools/htslib +.sp +File format specifications: http://samtools\&.github\&.io/hts\-specs +.sp +BCFtools documentation: http://samtools\&.github\&.io/bcftools +.sp +BCFtools wiki page: https://github\&.com/samtools/bcftools/wiki +.SH "COPYING" +.sp +The MIT/Expat License or GPL License, see the LICENSE document for details\&. Copyright (c) Genome Research Ltd\&. diff --git a/doc/bcftools.html b/doc/bcftools.html new file mode 100644 index 0000000..c178294 --- /dev/null +++ b/doc/bcftools.html @@ -0,0 +1,2683 @@ + + +bcftools

Name

bcftools — utilities for variant calling and manipulating VCFs and BCFs.

Synopsis

bcftools [--version|--version-only] [--help] [COMMAND] [OPTIONS]

DESCRIPTION

BCFtools is a set of utilities that manipulate variant calls in the Variant +Call Format (VCF) and its binary counterpart BCF. All commands work +transparently with both VCFs and BCFs, both uncompressed and BGZF-compressed.

Most commands accept VCF, bgzipped VCF and BCF with filetype detected +automatically even when streaming from a pipe. Indexed VCF and BCF +will work in all situations. Un-indexed VCF and BCF and streams will +work in most, but not all situations. In general, whenever multiple VCFs are +read simultaneously, they must be indexed and therefore also compressed.

BCFtools is designed to work on a stream. It regards an input file "-" as the +standard input (stdin) and outputs to the standard output (stdout). Several +commands can thus be combined with Unix pipes.

VERSION

This manual page was last updated 2017-05-08 and refers to bcftools git version 1.4.1.

BCF1

The BCF1 format output by versions of samtools <= 0.1.19 is not +compatible with this version of bcftools. To read BCF1 files one can use +the view command from old versions of bcftools packaged with samtools +versions <= 0.1.19 to convert to VCF, which can then be read by +this version of bcftools.

    samtools-0.1.19/bcftools/bcftools view file.bcf1 | bcftools view

VARIANT CALLING

See bcftools call for variant calling from the output of the +samtools mpileup command. In versions of samtools <= 0.1.19 calling was +done with bcftools view. Users are now required to choose between the old +samtools calling model (-c/--consensus-caller) and the new multiallelic +calling model (-m/--multiallelic-caller). The multiallelic calling model +is recommended for most tasks.

LIST OF COMMANDS

For a full list of available commands, run bcftools without arguments. For a full +list of available options, run bcftools COMMAND without arguments.

  • +annotate .. edit VCF files, add or remove annotations +
  • +call .. SNP/indel calling (former "view") +
  • +cnv .. Copy Number Variation caller +
  • +concat .. concatenate VCF/BCF files from the same set of samples +
  • +consensus .. create consensus sequence by applying VCF variants +
  • +convert .. convert VCF/BCF to other formats and back +
  • +csq .. haplotype aware consequence caller +
  • +filter .. filter VCF/BCF files using fixed thresholds +
  • +gtcheck .. check sample concordance, detect sample swaps and contamination +
  • +index .. index VCF/BCF +
  • +isec .. intersections of VCF/BCF files +
  • +merge .. merge VCF/BCF files files from non-overlapping sample sets +
  • +mpileup .. multi-way pileup producing genotype likelihoods +
  • +norm .. normalize indels +
  • +plugin .. run user-defined plugin +
  • +polysomy .. detect contaminations and whole-chromosome aberrations +
  • +query .. transform VCF/BCF into user-defined formats +
  • +reheader .. modify VCF/BCF header, change sample names +
  • +roh .. identify runs of homo/auto-zygosity +
  • +stats .. produce VCF/BCF stats (former vcfcheck) +
  • +view .. subset, filter and convert VCF and BCF files +

LIST OF SCRIPTS

Some helper scripts are bundled with the bcftools code.

COMMANDS AND OPTIONS

Common Options

The following options are common to many bcftools commands. See usage for +specific commands to see if they apply.

+FILE +
+ Files can be both VCF or BCF, uncompressed or BGZF-compressed. The file "-" + is interpreted as standard input. Some tools may require tabix- or + CSI-indexed files. +
+-c, --collapse snps|indels|both|all|some|none|id +

+ Controls how to treat records with duplicate positions and defines compatible + records across multiple input files. Here by "compatible" we mean records which + should be considered as identical by the tools. For example, when performing + line intersections, the desire may be to consider as identical all sites with + matching positions (bcftools isec -c all), or only sites with matching variant + type (bcftools isec -c snps  -c indels), or only sites with all alleles + identical (bcftools isec -c none). +

+none +
+ only records with identical REF and ALT alleles are compatible +
+some +
+ only records where some subset of ALT alleles match are compatible +
+all +
+ all records are compatible, regardless of whether the ALT alleles + match or not. In the case of records with the same position, only + the first will be considered and appear on output. +
+snps +
+ any SNP records are compatible, regardless of whether the ALT + alleles match or not. For duplicate positions, only the first SNP + record will be considered and appear on output. +
+indels +
+ all indel records are compatible, regardless of whether the REF + and ALT alleles match or not. For duplicate positions, only the + first indel record will be considered and appear on output. +
+both +
+ abbreviation of "-c indels  -c snps" +
+id +
+ only records with identical ID column are compatible. + Supported by bcftools merge only. +
+-f, --apply-filters LIST +
+ Skip sites where FILTER column does not contain any of the strings listed + in LIST. For example, to include only sites which have no filters set, + use -f .,PASS. +
+--no-version +
+ Do not append version and command line information to the output VCF header. +
+-o, --output FILE +
+ When output consists of a single stream, write it to FILE rather than + to standard output, where it is written by default. +
+-O, --output-type b|u|z|v +
+ Output compressed BCF (b), uncompressed BCF (u), compressed VCF (z), uncompressed VCF (v). + Use the -Ou option when piping between bcftools subcommands to speed up + performance by removing unnecessary compression/decompression and + VCF←→BCF conversion. +
+-r, --regions chr|chr:pos|chr:from-to|chr:from-[,…] +
+ Comma-separated list of regions, see also -R, --regions-file. Note + that -r cannot be used in combination with -R. +
+-R, --regions-file FILE +
+ Regions can be specified either on command line or in a VCF, BED, or + tab-delimited file (the default). The columns of the tab-delimited file + are: CHROM, POS, and, optionally, POS_TO, where positions are 1-based + and inclusive. The columns of the tab-delimited BED file are also + CHROM, POS and POS_TO (trailing columns are ignored), but coordinates + are 0-based, half-open. To indicate that a file be treated as BED rather + than the 1-based tab-delimited file, the file must have the ".bed" or + ".bed.gz" suffix (case-insensitive). Uncompressed files are stored in + memory, while bgzip-compressed and tabix-indexed region files are streamed. + Note that sequence names must match exactly, "chr20" is not the same as + "20". Also note that chromosome ordering in FILE will be respected, + the VCF will be processed in the order in which chromosomes first appear + in FILE. However, within chromosomes, the VCF will always be + processed in ascending genomic coordinate order no matter what order they + appear in FILE. Note that overlapping regions in FILE can result in + duplicated out of order positions in the output. + This option requires indexed VCF/BCF files. Note that -R cannot be used + in combination with -r. +
+-s, --samples [^]LIST +
+ Comma-separated list of samples to include or exclude if prefixed + with "^". + Note that in general tags such as INFO/AC, INFO/AN, etc are not updated + to correspond to the subset samples. bcftools view is the + exception where some tags will be updated (unless the -I, --no-update + option is used; see bcftools view documentation). To use updated + tags for the subset in another command one can pipe from view into + that command. For example: +
    bcftools view -Ou -s sample1,sample2 file.vcf | bcftools query -f %INFO/AC\t%INFO/AN\n
+-S, --samples-file FILE +
+ File of sample names to include or exclude if prefixed with "^". + One sample per line. See also the note above for the -s, --samples + option. + The command bcftools call accepts an optional second + column indicating ploidy (0, 1 or 2) or sex (as defined by + --ploidy, for example "F" or "M"), and can parse also PED + files. If the second column is not present, + the sex "F" is assumed. + With bcftools call -C trio, PED file is expected. File + formats examples: +
    sample1    1
+    sample2    2
+    sample3    2
+
+  or
+
+    sample1    M
+    sample2    F
+    sample3    F
+
+  or a .ped file (here is shown a minimum working example, the first column is
+  ignored and the last indicates sex: 1=male, 2=female)
+
+    ignored daughterA fatherA motherA 2
+    ignored sonB fatherB motherB 1
+-t, --targets [^]chr|chr:pos|chr:from-to|chr:from-[,…] +
+ Similar as -r, --regions, but the next position is accessed by streaming the + whole VCF/BCF rather than using the tbi/csi index. Both -r and -t options + can be applied simultaneously: -r uses the index to jump to a region + and -t discards positions which are not in the targets. Unlike -r, targets + can be prefixed with "^" to request logical complement. For example, "^X,Y,MT" + indicates that sequences X, Y and MT should be skipped. + Yet another difference between the two is that -r checks both start and + end positions of indels, whereas -t checks start positions only. Note + that -t cannot be used in combination with -T. +
+-T, --targets-file [^]FILE +
+ Same -t, --targets, but reads regions from a file. Note that -T + cannot be used in combination with -t. +
+ +
+ With the call -C alleles command, third column of the targets file must + be comma-separated list of alleles, starting with the reference allele. + Note that the file must be compressed and index. + Such a file can be easily created from a VCF using: +
    bcftools query -f'%CHROM\t%POS\t%REF,%ALT\n' file.vcf | bgzip -c > als.tsv.gz && tabix -s1 -b2 -e2 als.tsv.gz
+--threads INT +
+ Number of output compression threads to use in addition to main thread. + Only used when --output-type is b or z. Default: 0. +

bcftools annotate [OPTIONS] FILE

Add or remove annotations.

+-a, --annotations file +
+ Bgzip-compressed and tabix-indexed file with annotations. The file + can be VCF, BED, or a tab-delimited file with mandatory columns CHROM, POS + (or, alternatively, FROM and TO), optional columns REF and ALT, and arbitrary + number of annotation columns. BED files are expected to have + the ".bed" or ".bed.gz" suffix (case-insensitive), otherwise a tab-delimited file is assumed. + Note that in case of tab-delimited file, the coordinates POS, FROM and TO are + one-based and inclusive. When REF and ALT are present, only matching VCF + records will be annotated. + When multiple ALT alleles are present in the annotation file (given as + comma-separated list of alleles), at least one must match one of the + alleles in the corresponding VCF record. Similarly, at least one + alternate allele from a multi-allelic VCF record must be present in the + annotation file. + Note that flag types, such as "INFO/FLAG", can be annotated by including + a field with the value "1" to set the flag, "0" to remove it, or "." to + keep existing flags. + See also -c, --columns and -h, --header-lines. +
    # Sample annotation file with columns CHROM, POS, STRING_TAG, NUMERIC_TAG
+    1  752566  SomeString      5
+    1  798959  SomeOtherString 6
+    # etc.
+--collapse snps|indels|both|all|some|none +
+ Controls how to match records from the annotation file to the target VCF. + Effective only when -a is a VCF or BCF. + See Common Options for more. +
+-c, --columns list +
+ Comma-separated list of columns or tags to carry over from the annotation file + (see also -a, --annotations). If the annotation file is not a VCF/BCF, + list describes the columns of the annotation file and must include CHROM, + POS (or, alternatively, FROM and TO), and optionally REF and ALT. Unused + columns which should be ignored can be indicated by "-". + + If the annotation file is a VCF/BCF, only the edited columns/tags must be present and their + order does not matter. The columns ID, QUAL, FILTER, INFO and FORMAT + can be edited, where INFO tags can be written both as "INFO/TAG" or simply "TAG", + and FORMAT tags can be written as "FORMAT/TAG" or "FMT/TAG". + The imported VCF annotations can be renamed as "DST_TAG:=SRC_TAG" or "FMT/DST_TAG:=FMT/SRC_TAG". + + To carry over all INFO annotations, use "INFO". To add all INFO annotations except + "TAG", use "^INFO/TAG". By default, existing values are replaced. + + To add annotations without overwriting existing values (that is, to add missing tags or + add values to existing tags with missing values), use "+TAG" instead of "TAG". + To append to existing values (rather than replacing or leaving untouched), use "=TAG" + (instead of "TAG" or "+TAG"). + To replace only existing values without modifying missing annotations, use "-TAG". + + If the annotation file is not a VCF/BCF, all new annotations must be + defined via -h, --header-lines. +
+-e, --exclude EXPRESSION +
+ exclude sites for which EXPRESSION is true. For valid expressions see + EXPRESSIONS. +
+-h, --header-lines file +
+ Lines to append to the VCF header, see also -c, --columns and -a, --annotations. For example: +
    ##INFO=<ID=NUMERIC_TAG,Number=1,Type=Integer,Description="Example header line">
+    ##INFO=<ID=STRING_TAG,Number=1,Type=String,Description="Yet another header line">
+-I, --set-id [+]FORMAT +
+ assign ID on the fly. The format is the same as in the query + command (see below). By default all existing IDs are replaced. If the + format string is preceded by "+", only missing IDs will be set. For example, + one can use +
    bcftools annotate --set-id +'%CHROM\_%POS\_%REF\_%FIRST_ALT' file.vcf
+-i, --include EXPRESSION +
+ include only sites for which EXPRESSION is true. For valid expressions see + EXPRESSIONS. +
+-m, --mark-sites TAG +
+ annotate sites which are present ("+") or absent ("-") in the -a file with a new INFO/TAG flag +
+--no-version +
+ see Common Options +
+-o, --output FILE +
+ see Common Options +
+-O, --output-type b|u|z|v +
+ see Common Options +
+-r, --regions chr|chr:pos|chr:from-to|chr:from-[,…] +
+ see Common Options +
+-R, --regions-file file +
+ see Common Options +
+--rename-chrs file +
+ rename chromosomes according to the map in file, with + "old_name new_name\n" pairs separated by whitespaces, each on a separate + line. +
+-s, --samples [^]LIST +
+ subset of samples to annotate, see also Common Options +
+-S, --samples-file FILE +
+ subset of samples to annotate. If the samples are named differently in the + target VCF and the -a, --annotations VCF, the name mapping can be + given as "src_name dst_name\n", separated by whitespaces, each pair on a + separate line. +
+--threads INT +
+ see Common Options +
+-x, --remove list +
+ List of annotations to remove. Use "FILTER" to remove all filters or + "FILTER/SomeFilter" to remove a specific filter. Similarly, "INFO" can + be used to remove all INFO tags and "FORMAT" to remove all FORMAT tags + except GT. To remove all INFO tags except "FOO" and "BAR", use + "^INFO/FOO,INFO/BAR" (and similarly for FORMAT and FILTER). + "INFO" can be abbreviated to "INF" and "FORMAT" to "FMT". +

Examples:

    # Remove three fields
+    bcftools annotate -x ID,INFO/DP,FORMAT/DP file.vcf.gz
+
+    # Remove all INFO fields and all FORMAT fields except for GT and PL
+    bcftools annotate -x INFO,^FORMAT/GT,FORMAT/PL file.vcf
+
+    # Add ID, QUAL and INFO/TAG, not replacing TAG if already present
+    bcftools annotate -a src.bcf -c ID,QUAL,+TAG dst.bcf
+
+    # Carry over all INFO and FORMAT annotations except FORMAT/GT
+    bcftools annotate -a src.bcf -c INFO,^FORMAT/GT dst.bcf
+
+    # Annotate from a tab-delimited file with six columns (the fifth is ignored),
+    # first indexing with tabix. The coordinates are 1-based.
+    tabix -s1 -b2 -e2 annots.tab.gz
+    bcftools annotate -a annots.tab.gz -h annots.hdr -c CHROM,POS,REF,ALT,-,TAG file.vcf
+
+    # Annotate from a tab-delimited file with regions (1-based coordinates, inclusive)
+    tabix -s1 -b2 -e3 annots.tab.gz
+    bcftools annotate -a annots.tab.gz -h annots.hdr -c CHROM,FROM,TO,TAG inut.vcf
+
+    # Annotate from a bed file (0-based coordinates, half-closed, half-open intervals)
+    bcftools annotate -a annots.bed.gz -h annots.hdr -c CHROM,FROM,TO,TAG input.vcf

bcftools call [OPTIONS] FILE

This command replaces the former bcftools view caller. Some of the original +functionality has been temporarily lost in the process of transition under +htslib, but will be added back on popular +demand. The original calling model can be invoked with the -c option.

File format options:

+--no-version +
+ see Common Options +
+-o, --output FILE +
+ see Common Options +
+-O, --output-type b|u|z|v +
+ see Common Options +
+--ploidy ASSEMBLY[?] +
+ predefined ploidy, use list (or any other unused word) to print a list + of all predefined assemblies. Append a question mark to print the actual + definition. See also --ploidy-file. +
+--ploidy-file FILE +
+ ploidy definition given as a space/tab-delimited list of + CHROM, FROM, TO, SEX, PLOIDY. The SEX codes are arbitrary and + correspond to the ones used by --samples-file. + The default ploidy can be given using the starred records (see + below), unlisted regions have ploidy 2. The default ploidy definition is +
    X 1 60000 M 1
+    X 2699521 154931043 M 1
+    Y 1 59373566 M 1
+    Y 1 59373566 F 0
+    MT 1 16569 M 1
+    MT 1 16569 F 1
+    *  * *     M 2
+    *  * *     F 2
+-r, --regions chr|chr:pos|chr:from-to|chr:from-[,…] +
+ see Common Options +
+-R, --regions-file file +
+ see Common Options +
+-s, --samples LIST +
+ see Common Options +
+-S, --samples-file FILE +
+ see Common Options +
+-t, --targets LIST +
+ see Common Options +
+-T, --targets-file FILE +
+ see Common Options +
+--threads INT +
+ see Common Options +

Input/output options:

+-A, --keep-alts +
+ output all alternate alleles present in the alignments even if they do not + appear in any of the genotypes +
+-f, --format-fields list +
+ comma-separated list of FORMAT fields to output for each sample. Currently + GQ and GP fields are supported. For convenience, the fields can be given + as lower case letters. +
+-F, --prior-freqs AN,AC +
+ take advantage of prior knowledge of population allele frequencies. The + workflow looks like this: +
    # Extract AN,AC values from an existing VCF, such 1000Genomes
+    bcftools query -f'%CHROM\t%POS\t%REF\t%ALT\t%AN\t%AC\n' 1000Genomes.bcf | bgzip -c > AFs.tab.gz
+
+    # If the tags AN,AC are not already present, use the +fill-AN-AC plugin
+    bcftools +fill-AN-AC 1000Genomes.bcf | bcftools query -f'%CHROM\t%POS\t%REF\t%ALT\t%AN\t%AC\n' | bgzip -c > AFs.tab.gz
+    tabix -s1 -b2 -e2 AFs.tab.gz
+
+    # Create a VCF header description, here we name the tags REF_AN,REF_AC
+    cat AFs.hdr
+    ##INFO=<ID=REF_AN,Number=1,Type=Integer,Description="Total number of alleles in reference genotypes">
+    ##INFO=<ID=REF_AC,Number=A,Type=Integer,Description="Allele count in reference genotypes for each ALT allele">
+
+    # Now before calling, stream the raw mpileup output through `bcftools annotate` to add the frequencies
+    bcftools mpileup [...] -Ou | bcftools annotate -a AFs.tab.gz -h AFs.hdr -c CHROM,POS,REF,ALT,REF_AN,REF_AC -Ou | bcftools call -mv -F REF_AN,REF_AC [...]
+-g, --gvcf INT +
+ output also gVCF blocks of homozygous REF calls. The parameter INT is the + minimum per-sample depth required to include a site in the non-variant + block. +
+-i, --insert-missed INT +
+ output also sites missed by mpileup but present in -T, --targets-file. +
+-M, --keep-masked-ref +
+ output sites where REF allele is N +
+-V, --skip-variants snps|indels +
+ skip indel/SNP sites +
+-v, --variants-only +
+ output variant sites only +

Consensus/variant calling options:

+-c, --consensus-caller +
+ the original samtools/bcftools calling method (conflicts with -m) +
+-C, --constrain alleles|trio +
+alleles +
+ call genotypes given alleles. See also -T, --targets-file. +
+trio +
+ call genotypes given the father-mother-child constraint. See also + -s, --samples and -n, --novel-rate. +
+-m, --multiallelic-caller +
+ alternative modelfor multiallelic and rare-variant calling designed to + overcome known limitations in -c calling model (conflicts with -c) +
+-n, --novel-rate float[,…] +
+ likelihood of novel mutation for constrained -C trio calling. The trio + genotype calling maximizes likelihood of a particular combination of + genotypes for father, mother and the child + P(F=i,M=j,C=k) = P(unconstrained) * Pn + P(constrained) * (1-Pn). + By providing three values, the mutation rate Pn is set explicitly for SNPs, + deletions and insertions, respectively. If two values are given, the first + is interpreted as the mutation rate of SNPs and the second is used to + calculate the mutation rate of indels according to their length as + Pn=float*exp(-a-b*len), where a=22.8689, b=0.2994 for insertions and + a=21.9313, b=0.2856 for deletions [pubmed:23975140]. If only one value is + given, the same mutation rate Pn is used for SNPs and indels. +
+-p, --pval-threshold float +
+ with -c, accept variant if P(ref|D) < float. +
+-P, --prior float +
+ expected substitution rate, or 0 to disable the prior. Only with -m. +
+-t, --targets file|chr|chr:pos|chr:from-to|chr:from-[,…] +
+ see Common Options +
+-X, --chromosome-X +
+ haploid output for male samples (requires PED file with -s) +
+-Y, --chromosome-Y +
+ haploid output for males and skips females (requires PED file with -s) +

bcftools cnv [OPTIONS] FILE

Copy number variation caller, requires a VCF annotated with the Illumina’s +B-allele frequency (BAF) and Log R Ratio intensity (LRR) values. The HMM +considers the following copy number states: CN 2 (normal), 1 (single-copy +loss), 0 (complete loss), 3 (single-copy gain).

General Options:

+-c, --control-sample string +
+ optional control sample name. If given, pairwise calling is performed + and the -P option can be used +
+-f, --AF-file file +
+ read allele frequencies from a tab-delimited file with the columns CHR,POS,REF,ALT,AF +
+*-o, --output-dir path +
+ output directory +
+*-p, --plot-threshold float +
+ call matplotlib to produce plots for chromosomes with quality at least float, + useful for visual inspection of the calls. With -p 0, plots for all chromosomes will be + generated. If not given, a matplotlib script will be created but not called. +
+-r, --regions chr|chr:pos|chr:from-to|chr:from-[,…] +
+ see Common Options +
+-R, --regions-file file +
+ see Common Options +
+-s, --query-sample string +
+ query samply name +
+-t, --targets LIST +
+ see Common Options +
+-T, --targets-file FILE +
+ see Common Options +

HMM Options:

+-a, --aberrant float[,float] +
+ fraction of aberrant cells in query and control. The hallmark of + duplications and contaminations is the BAF value of heterozygous markers + which is dependent on the fraction of aberrant cells. Sensitivity to + smaller fractions of cells can be increased by setting -a to a lower value. Note + however, that this comes at the cost of increased false discovery rate. +
+-b, --BAF-weight float +
+ relative contribution from BAF +
+d, --BAF-dev float[,float] +
+ expected BAF deviation in query and control, i.e. the noise observed + in the data. +
+-e, --err-prob float +
+ uniform error probability +
+-l, --LRR-weight float +
+ relative contribution from LRR. With noisy data, this option can have big effect + on the number of calls produced. In truly random noise (such as in simulated data), + the value should be set high (1.0), but in the presence of systematic noise + when LRR are not informative, lower values result in cleaner calls (0.2). +
+-L, --LRR-smooth-win int +
+ reduce LRR noise by applying moving average given this window size +
+-O, --optimize float +
+ iteratively estimate the fraction of aberrant cells, down to the given fraction. + Lowering this value from the default 1.0 to say, 0.3, can help discover more + events but also increases noise +
+-P, --same-prob float +
+ the prior probability of the query and the control sample being the same. + Setting to 0 calls both independently, setting to 1 forces the same copy + number state in both. +
+-x, --xy-prob float +
+ the HMM probability of transition to another copy number state. Increasing this + values leads to smaller and more frequent calls. +

bcftools concat [OPTIONS] FILE1 FILE2 […]

Concatenate or combine VCF/BCF files. All source files must have the same sample +columns appearing in the same order. Can be used, for example, to +concatenate chromosome VCFs into one VCF, or combine a SNP VCF and an indel +VCF into one. The input files must be sorted by chr and position. The files +must be given in the correct order to produce sorted VCF on output unless +the -a, --allow-overlaps option is specified. With the --naive option, the files +are concatenated without being recompressed, which is very fast but dangerous +if the BCF headers differ.

+-a, --allow-overlaps +
+ First coordinate of the next file can precede last record of the current file. +
+-c, --compact-PS +
+ Do not output PS tag at each site, only at the start of a new phase set block. +
+-d, --rm-dups snps|indels|both|all|none +
+ Output duplicate records of specified type present in multiple files only once. + Requires -a, --allow-overlaps. +
+-D, --remove-duplicates +
+ Alias for -d none +
+-f, --file-list FILE +
+ Read file names from FILE, one file name per line. +
+-l, --ligate +
+ Ligate phased VCFs by matching phase at overlapping haplotypes +
+--no-version +
+ see Common Options +
+-n, --naive +
+ Concatenate VCF or BCF files without recompression. This is very fast but requires + that all files are of the same type (all VCF or all BCF) and have the same headers. + This is because all tags and chromosome names in the BCF body rely on the implicit + order of the contig and tag definitions in the header. Currently no sanity checks + are in place. Dangerous, use with caution. +
+-o, --output FILE +
+ see Common Options +
+-O, --output-type b|u|z|v +
+ see Common Options +
+-q, --min-PQ INT +
+ Break phase set if phasing quality is lower than INT +
+-r, --regions chr|chr:pos|chr:from-to|chr:from-[,…] +
+ see Common Options. Requires -a, --allow-overlaps. +
+-R, --regions-file FILE +
+ see Common Options. Requires -a, --allow-overlaps. +
+--threads INT +
+ see Common Options +

bcftools consensus [OPTIONS] FILE

Create consensus sequence by applying VCF variants to a reference fasta file. +By default, the program will apply all ALT variants to the reference fasta to +obtain the consensus sequence. Using the --sample (and, optionally, +--haplotype) option will apply genotype (haplotype) calls from FORMAT/GT. +Note that the program does not act as a primitive variant caller and ignores allelic +depth information, such as INFO/AD or FORMAT/AD. For that, consider using the +setGT plugin.

+-f, --fasta-ref FILE +
+ reference sequence in fasta format +
+-H, --haplotype 1|2 +
+ apply variants for the given haplotype. This option requires -s, unless + exactly one sample is present in the VCF +
+-i, --iupac-codes +
+ output variants in the form of IUPAC ambiguity codes +
+-m, --mask FILE +
+ BED file or TAB file with regions to be replaced with N. See discussion + of --regions-file in Common Options for file + format details. +
+-o, --output FILE +
+ write output to a file +
+-s, --sample NAME +
+ apply variants of the given sample +

Examples:

    # Apply variants present in sample "NA001", output IUPAC codes for hets
+    bcftools consensus -i -s NA001 -f in.fa in.vcf.gz > out.fa
+
+    # Create consensus for one region. The fasta header lines are then expected
+    # in the form ">chr:from-to".
+    samtools faidx ref.fa 8:11870-11890 | bcftools consensus in.vcf.gz -o out.fa

bcftools convert [OPTIONS] FILE

VCF input options:

+-e, --exclude EXPRESSION +
+ exclude sites for which EXPRESSION is true. For valid expressions see + EXPRESSIONS. +
+-i, --include EXPRESSION +
+ include only sites for which EXPRESSION is true. For valid expressions see + EXPRESSIONS. +
+-r, --regions chr|chr:pos|chr:from-to|chr:from-[,…] +
+ see Common Options +
+-R, --regions-file FILE +
+ see Common Options +
+-s, --samples LIST +
+ see Common Options +
+-S, --samples-file FILE +
+ see Common Options +
+-t, --targets LIST +
+ see Common Options +
+-T, --targets-file FILE +
+ see Common Options +

VCF output options:

+--no-version +
+ see Common Options +
+-o, --output FILE +
+ see Common Options +
+-O, --output-type b|u|z|v +
+ see Common Options +
+--threads INT +
+ see Common Options +

GEN/SAMPLE conversion:

+-G, --gensample2vcf prefix or gen-file,sample-file +
+ convert IMPUTE2 output to VCF. The second column must be of the form + "CHROM:POS_REF_ALT" to detect possible strand swaps; IMPUTE2 leaves the + first one empty ("--") when sites from reference panel are filled in. See + also -g below. +
+-g, --gensample prefix or gen-file,sample-file +
+ convert from VCF to gen/sample format used by IMPUTE2 and SHAPEIT. + The columns of .gen file format are ID1,ID2,POS,A,B followed by three + genotype probabilities P(AA), P(AB), P(BB) for each sample. In order to + prevent strand swaps, the program uses IDs of the form "CHROM:POS_REF_ALT". + For example: +
  .gen
+  ----
+  1:111485207_G_A 1:111485207_G_A 111485207 G A 0 1 0 0 1 0
+  1:111494194_C_T 1:111494194_C_T 111494194 C T 0 1 0 0 0 1
+
+  .sample
+  -------
+  ID_1 ID_2 missing
+  0 0 0
+  sample1 sample1 0
+  sample2 sample2 0
+--tag STRING +
+ tag to take values for .gen file: GT,PL,GL,GP +
+--chrom +
+ output chromosome in the first column instead of CHROM:POS_REF_ALT +
+--sex FILE +
+ output sex column in the sample file. The FILE format is +
    MaleSample    M
+    FemaleSample  F
+--vcf-ids +
+ output VCF IDs in the second column instead of CHROM:POS_REF_ALT +

gVCF conversion:

+--gvcf2vcf +
+ convert gVCF to VCF, expanding REF blocks into sites. Only sites + with FILTER set to "PASS" or "." will be expanded. +
+-f, --fasta-ref file +
+ reference sequence in fasta format. Must be indexed with samtools faidx +

HAPS/SAMPLE conversion:

+--hapsample2vcf prefix or haps-file,sample-file +
+ convert from haps/sample format to VCF. The columns of .haps file are + similar to .gen file above, but there are only two haplotype columns per + sample. Note that the first column of the haps file is expected to be in + the form "CHR:POS_REF_ALT(_END)?", with the _END being optional for + defining the INFO/END tag when ALT is a symbolic allele, for example: +
  .haps
+  ----
+  1:111485207_G_A rsID1 111485207 G A 0 1 0 0
+  1:111494194_C_T rsID2 111494194 C T 0 1 0 0
+  1:111495231_A_<DEL>_111495784 rsID3 111495231 A <DEL> 0 0 1 0
+--hapsample prefix or haps-file,sample-file +
+ convert from VCF to haps/sample format used by IMPUTE2 and SHAPEIT. + The columns of .haps file begin with ID,RSID,POS,REF,ALT. In order to + prevent strand swaps, the program uses IDs of the form + "CHROM:POS_REF_ALT". +
+--haploid2diploid +
+ with -h option converts haploid genotypes to homozygous diploid + genotypes. For example, the program will print 0 0 instead of the + default 0 -. This is useful for programs which do not handle haploid + genotypes correctly. +
+--sex FILE +
+ output sex column in the sample file. The FILE format is +
    MaleSample    M
+    FemaleSample  F
+--vcf-ids +
+ output VCF IDs instead of "CHROM:POS_REF_ALT" IDs +

HAPS/LEGEND/SAMPLE conversion:

+-H, --haplegendsample2vcf prefix or haps-file,legend-file,sample-file +
+ convert from haps/legend/sample format used by IMPUTE2 to VCF, see + also -h, --hapslegendsample below. +
+-h, --haplegendsample prefix or haps-file,legend-file,sample-file +
+ convert from VCF to haps/legend/sample format used by IMPUTE2 and SHAPEIT. + The columns of .legend file ID,POS,REF,ALT. In order to prevent strand + swaps, the program uses IDs of the form "CHROM:POS_REF_ALT". The .sample + file is quite basic at the moment with columns for population, group and + sex expected to be edited by the user. For example: +
  .haps
+  -----
+  0 1 0 0 1 0
+  0 1 0 0 0 1
+
+  .legend
+  -------
+  id position a0 a1
+  1:111485207_G_A 111485207 G A
+  1:111494194_C_T 111494194 C T
+
+  .sample
+  -------
+  sample population group sex
+  sample1 sample1 sample1 2
+  sample2 sample2 sample2 2
+--haploid2diploid +
+ with -h option converts haploid genotypes to homozygous diploid + genotypes. For example, the program will print 0 0 instead of the + default 0 -. This is useful for programs which do not handle haploid + genotypes correctly. +
+--sex FILE +
+ output sex column in the sample file. The FILE format is +
    MaleSample    M
+    FemaleSample  F
+--vcf-ids +
+ output VCF IDs instead of "CHROM:POS_REF_ALT" IDs +

TSV conversion:

+--tsv2vcf file +
+ convert from TSV (tab-separated values) format (such as generated by + 23andMe) to VCF. The input file fields can be tab- or space- delimited +
+-c, --columns list +
+ comma-separated list of fields in the input file. In the current + version, the fields CHROM, POS, ID, and AA are expected and + can appear in arbitrary order, columns which should be ignored in the input + file can be indicated by "-". + The AA field lists alleles on the forward reference strand, + for example "CC" or "CT" for diploid genotypes or "C" + for haploid genotypes (sex chromosomes). Insertions and deletions + are not supported yet, missing data can be indicated with "--". +
+-f, --fasta-ref file +
+ reference sequence in fasta format. Must be indexed with samtools faidx +
+-s, --samples LIST +
+ list of sample names. See Common Options +
+-S, --samples-file FILE +
+ file of sample names. See Common Options +

Example:

# Convert 23andme results into VCF
+bcftools convert -c ID,CHROM,POS,AA -s SampleName -f 23andme-ref.fa --tsv2vcf 23andme.txt -Oz -o out.vcf.gz

bcftools csq [OPTIONS] FILE

Haplotype aware consequence predictor which correctly handles combined +variants such as MNPs split over multiple VCF records, SNPs separated by +an intron (but adjacent in the spliced transcript) or nearby frame-shifting +indels which in combination in fact are not frame-shifting.

The output VCF is annotated with INFO/BCSQ and FORMAT/BCSQ tag (configurable +with the -c option). The latter is a bitmask of indexes to INFO/BCSQ, with +interleaved haplotypes. See the usage examples below for using the %TBCSQ +converter in query for extracting a more human readable form from this +bitmask. The contruction of the bitmask limits the number of consequences +that can be referenced in the FORMAT/BCSQ tags. By default this is 16, but +if more are required, see the --ncsq option.

The program requires on input a VCF/BCF file, the reference genome in fasta +format (--fasta-ref) and genomic features in the GFF3 format downloadable +from the Ensembl website (--gff-annot), and outputs an annotated VCF/BCF +file. Currently, only Ensembl GFF3 files are supported.

By default, the input VCF should be phased. If phase is unknown, or only +partially known, the --phase option can be used to indicate how to handle +unphased data. Alternatively, haplotype aware calling can be turned off +with the --local-csq option.

If conflicting (overlapping) variants within one haplotype are detected, +a warning will be emitted and predictions will be based on only the first +variant in the analysis.

Symbolic alleles are not supported. They will remain unannotated in the +output VCF and are ignored for the prediction analysis.

+-c, --custom-tag STRING +
+ use this custom tag to store consequences rather than the default BCSQ tag +
+-e, --exclude EXPRESSION +
+ exclude sites for which EXPRESSION is true. For valid expressions see + EXPRESSIONS. +
+-f, --fasta-ref FILE +
+ reference sequence in fasta format (required) +
+-g, --gff-annot FILE +
+ GFF3 annotation file (required), such as ftp://ftp.ensembl.org/pub/current_gff3/homo_sapiens/ +
+-i, --include EXPRESSION +
+ include only sites for which EXPRESSION is true. For valid expressions see + EXPRESSIONS. +
+-l, --local-csq +
+ switch off haplotype-aware calling, run localized predictions considering + only one VCF record at a time +
+-n, --ncsq INT +
+ maximum number of consequences to consider per site. The INFO/BCSQ column includes + all consequences, but only the first INT will be referenced by the FORMAT/BCSQ fields. + The default value is 16 which corresponds to one integer per diploid + sample. Note that increasing the value leads to increased memory and is rarely necessary. +
+-o, --output FILE +
+ see Common Options +
+-O, --output-type b|t|u|z|v +
+ see Common Options. In addition, a custom tab-delimited + plain text output can be printed (t). +
+-p, --phase a|m|r|R|s +

+ how to construct haplotypes and how to deal with unphased data: +

+a +
+ take GTs as is, create haplotypes regardless of phase (0/1 → 0|1) +
+m +
+ merge all GTs into a single haplotype (0/1 → 1, 1/2 → 1) +
+r +
+ require phased GTs, throw an error on unphased heterozygous GTs +
+R +
+ create non-reference haplotypes if possible (0/1 → 1|1, 1/2 → 1|2) +
+s +
+ skip unphased GTs +
+-q, --quiet +
+ suppress warning messages +
+-r, --regions chr|chr:pos|chr:from-to|chr:from-[,…] +
+ see Common Options +
+-R, --regions-file FILE +
+ see Common Options +
+-s, --samples LIST +
+ samples to include or "-" to apply all variants and ignore samples +
+-S, --samples-file FILE +
+ see Common Options +
+-t, --targets LIST +
+ see Common Options +
+-T, --targets-file FILE +
+ see Common Options +

Examples:

    # Basic usage
+    bcftools csq -f hs37d5.fa -g Homo_sapiens.GRCh37.82.gff3.gz in.vcf -Ob -o out.bcf
+
+    # Extract the translated haplotype consequences. The following TBCSQ variations
+    # are recognised:
+    #   %TBCSQ    .. print consequences in all haplotypes in separate columns
+    #   %TBCSQ{0} .. print the first haplotype only
+    #   %TBCSQ{1} .. print the second haplotype only
+    #   %TBCSQ{*} .. print a list of unique consquences present in either haplotype
+    bcftools query -f'[%CHROM\t%POS\t%SAMPLE\t%TBCSQ\n]' out.bcf

Examples of BCSQ annotation:

    # Two separate VCF records at positions 2:122106101 and 2:122106102
+    # change the same codon. This UV-induced C>T dinucleotide mutation
+    # has been annotated fully at the position 2:122106101 with
+    #   - consequence type
+    #   - gene name
+    #   - ensembl transcript ID
+    #   - coding strand (+ fwd, - rev)
+    #   - amino acid position (in the coding strand orientation)
+    #   - list of corresponding VCF variants
+    # The annotation at the second position gives the position of the full
+    # annotation
+    BCSQ=missense|CLASP1|ENST00000545861|-|1174P>1174L|122106101G>A+122106102G>A
+    BCSQ=@122106101
+
+    # A frame-restoring combination of two frameshift insertions C>CG and T>TGG
+    BCSQ=@46115084
+    BCSQ=inframe_insertion|COPZ2|ENST00000006101|-|18AGRGP>18AQAGGP|46115072C>CG+46115084T>TGG
+
+    # Stop gained variant
+    BCSQ=stop_gained|C2orf83|ENST00000264387|-|141W>141*|228476140C>T
+
+    # The consequence type of a variant downstream from a stop are prefixed with *
+    BCSQ=*missense|PER3|ENST00000361923|+|1028M>1028T|7890117T>C

bcftools filter [OPTIONS] FILE

Apply fixed-threshold filters.

+-e, --exclude EXPRESSION +
+ exclude sites for which EXPRESSION is true. For valid expressions see + EXPRESSIONS. +
+-g, --SnpGap INT +
+ filter SNPs within INT base pairs of an indel. The following example + demonstrates the logic of --SnpGap 3 applied on a deletion and + an insertion: +
The SNPs at positions 1 and 7 are filtered, positions 0 and 8 are not:
+         0123456789
+    ref  .G.GT..G..
+    del  .A.G-..A..
+Here the positions 1 and 6 are filtered, 0 and 7 are not:
+         0123-456789
+    ref  .G.G-..G..
+    ins  .A.GT..A..
+-G, --IndelGap INT +
+ filter clusters of indels separated by INT or fewer base pairs allowing + only one to pass. The following example demonstrates the logic of + --IndelGap 2 applied on a deletion and an insertion: +
The second indel is filtered:
+         012345678901
+    ref  .GT.GT..GT..
+    del  .G-.G-..G-..
+And similarly here, the second is filtered:
+         01 23 456 78
+    ref  .A-.A-..A-..
+    ins  .AT.AT..AT..
+-i, --include EXPRESSION +
+ include only sites for which EXPRESSION is true. For valid expressions see + EXPRESSIONS. +
+-m, --mode [+x] +
+ define behaviour at sites with existing FILTER annotations. The default + mode replaces existing filters of failed sites with a new FILTER string + while leaving sites which pass untouched when non-empty and setting to + "PASS" when the FILTER string is absent. The "+" mode appends new FILTER + strings of failed sites instead of replacing them. The "x" mode resets + filters of sites which pass to "PASS". Modes "+" and "x" can both be set. +
+--no-version +
+ see Common Options +
+-o, --output FILE +
+ see Common Options +
+-O, --output-type b|u|z|v +
+ see Common Options +
+-r, --regions chr|chr:pos|chr:from-to|chr:from-[,…] +
+ see Common Options +
+-R, --regions-file file +
+ see Common Options +
+-s, --soft-filter STRING|+ +
+ annotate FILTER column with STRING or, with +, a unique filter name generated + by the program ("Filter%d"). +
+-S, --set-GTs .|0 +
+ set genotypes of failed samples to missing value (.) or reference allele (0) +
+-t, --targets chr|chr:pos|chr:from-to|chr:from-[,…] +
+ see Common Options +
+-T, --targets-file file +
+ see Common Options +
+--threads INT +
+ see Common Options +

bcftools gtcheck [OPTIONS] [-g genotypes.vcf.gz] query.vcf.gz

Checks sample identity or, without -g, multi-sample cross-check is performed.

+-a, --all-sites +
+ output for all sites +
+-c, --cluster FLOAT,FLOAT +

+ min inter- and max intra-sample error [0.23,-0.3] +

The first "min" argument controls the typical error rate in multiplexed
+runs ("lanelets") from the same sample. Lanelets with error rate less
+than this will always be considered as coming from the same sample.
+The second "max" argument is the reverse: lanelets with error rate
+greater than the absolute value of this parameter will always be
+considered as different samples. When the value is negative, the cutoff
+may be heuristically lowered by the clustering engine. If positive, the
+value is interpreted as a fixed cutoff.
+-g, --genotypes genotypes.vcf.gz +
+ reference genotypes to compare against +
+-G, --GTs-only INT +
+ use genotypes (GT) instead of genotype likelihoods (PL). When set to 1, + reported discordance is the number of non-matching GTs, otherwise the + number INT is interpreted as phred-scaled likelihood of unobserved + genotypes. +
+-H, --homs-only +
+ consider only genotypes which are homozygous in both genotypes and + query VCF. This may be useful with low coverage data. +
+-p, --plot PREFIX +
+ produce plots +
+-r, --regions chr|chr:pos|chr:from-to|chr:from-[,…] +
+ see Common Options +
+-R, --regions-file file +
+ see Common Options +
+-s, --query-sample STRING +
+ query sample in query.vcf.gz. By default, the first sample is checked. +
+-S, --target-sample STRING +
+ target sample in the -g file, used only for plotting, not for analysis +
+-t, --targets file +
+ see Common Options +
+-T, --targets-file file +
+ see Common Options +

Output files format:

+CN, Discordance +
+ Pairwise discordance for all sample pairs is calculated as +
        \sum_s { min_G { PL_a(G) + PL_b(G) } },
+ +
+ where the sum runs over all sites s and G is the the most likely + genotype shared by both samples a and b. When PL field is not + present, a constant value 99 is used for the unseen genotypes. With + -G, the value 1 can be used instead; the discordance value then + gives exactly the number of differing genotypes. +
+SM, Average Discordance +
+ Average discordance between sample a and all other samples. +
+SM, Average Depth +
+ Average depth at evaluated sites, or 1 if FORMAT/DP field is not + present. +
+SM, Average Number of sites +
+ The average number of sites used to calculate the discordance. In + other words, the average number of non-missing PLs/genotypes seen + both samples. +

bcftools index [OPTIONS] in.bcf|in.vcf.gz

Creates index for bgzip compressed VCF/BCF files for random access. CSI +(coordinate-sorted index) is created by default. The CSI format +supports indexing of chromosomes up to length 2^31. TBI (tabix index) +index files, which support chromosome lengths up to 2^29, can be +created by using the -t/--tbi option or using the tabix program +packaged with htslib. When loading an index file, bcftools will try +the CSI first and then the TBI.

Indexing options:

+-c, --csi +
+ generate CSI-format index for VCF/BCF files [default] +
+-f, --force +
+ overwrite index if it already exists +
+-m, --min-shift INT +
+ set minimal interval size for CSI indices to 2^INT; default: 14 +
+-o, --output-file FILE +
+ output file name. If not set, then the index will be created + using the input file name plus a .csi or .tbi extension +
+-t, --tbi +
+ generate TBI-format index for VCF files +
+--threads INT +
+ see Common Options +

Stats options:

+-n, --nrecords +
+ print the number of records based on the CSI or TBI index files +
+-s, --stats +
+ Print per contig stats based on the CSI or TBI index files. + Output format is three tab-delimited columns listing the contig + name, contig length (. if unknown) and number of records for + the contig. Contigs with zero records are not printed. +

bcftools isec [OPTIONS] A.vcf.gz B.vcf.gz […]

Creates intersections, unions and complements of VCF files. Depending +on the options, the program can output records from one (or more) files +which have (or do not have) corresponding records with the same position +in the other files.

+-c, --collapse snps|indels|both|all|some|none +
+ see Common Options +
+-C, --complement +
+ output positions present only in the first file but missing in the others +
+-e, --exclude -|EXPRESSION +
+ exclude sites for which EXPRESSION is true. If -e (or -i) + appears only once, the same filtering expression will be applied to all + input files. Otherwise, -e or -i must be given for each input file. + To indicate that no filtering should be performed on a file, use "-" in + place of EXPRESSION, as shown in the example below. + For valid expressions see EXPRESSIONS. +
+-f, --apply-filters LIST +
+ see Common Options +
+-i, --include EXPRESSION +
+ include only sites for which EXPRESSION is true. See discussion + of -e, --exclude above. +
+-n, --nfiles [+-=]INT|~BITMAP +
+ output positions present in this many (=), this many or more (+), this + many or fewer (-), or the exact same (~) files +
+-o, --output FILE +
+ see Common Options. When several files are being + output, their names are controlled via -p instead. +
+-O, --output-type b|u|z|v +
+ see Common Options +
+-p, --prefix DIR +
+ if given, subset each of the input files accordingly. See also -w. +
+-r, --regions chr|chr:pos|chr:from-to|chr:from-[,…] +
+ see Common Options +
+-R, --regions-file file +
+ see Common Options +
+-t, --targets chr|chr:pos|chr:from-to|chr:from-[,…] +
+ see Common Options +
+-T, --targets-file file +
+ see Common Options +
+-w, --write LIST +
+ list of input files to output given as 1-based indices. With -p and no + -w, all files are written. +

Examples:

Create intersection and complements of two sets saving the output in dir/*

    bcftools isec -p dir A.vcf.gz B.vcf.gz

Filter sites in A and B (but not in C) and create intersection

    bcftools isec -e'MAF<0.01' -i'dbSNP=1' -e- A.vcf.gz B.vcf.gz C.vcf.gz -p dir

Extract and write records from A shared by both A and B using exact allele match

    bcftools isec -p dir -n=2 -w1 A.vcf.gz B.vcf.gz

Extract records private to A or B comparing by position only

    bcftools isec -p dir -n-1 -c all A.vcf.gz B.vcf.gz

Print a list of records which are present in A and B but not in C and D

    bcftools isec -n~1100 -c all A.vcf.gz B.vcf.gz C.vcf.gz D.vcf.gz

bcftools merge [OPTIONS] A.vcf.gz B.vcf.gz […]

Merge multiple VCF/BCF files from non-overlapping sample sets to create one +multi-sample file. For example, when merging file A.vcf.gz containing +samples S1, S2 and S3 and file B.vcf.gz containing samples S3 and +S4, the output file will contain four samples named S1, S2, S3, 2:S3 +and S4.

Note that it is responsibility of the user to ensure that the sample names are +unique across all files. If they are not, the program will exit with an error +unless the option --force-samples is given. The sample names can be +also given explicitly using the --print-header and --use-header options.

Note that only records from different files can be merged, never from the same file. +For "vertical" merge take a look at bcftools norm instead.

+--force-samples +
+ if the merged files contain duplicate samples names, proceed anyway. + Duplicate sample names will be resolved by prepending index of the file + as it appeared on the command line to the conflicting sample name (see + 2:S3 in the above example). +
+--print-header +
+ print only merged header and exit +
+--use-header FILE +
+ use the VCF header in the provided text FILE +
+-0 --missing-to-ref +
+ assume genotypes at missing sites are 0/0 +
+-f, --apply-filters LIST +
+ see Common Options +
+-F, --filter-logic x|+ +
+ Set the output record to PASS if any of the inputs is PASS (x), + or apply all filters (+), which is the default. +
+-g, --gvcf -|FILE +
+ merge gVCF blocks, INFO/END tag is expected. If the reference fasta + file FILE is not given and the dash (-) is given, unknown reference + bases generated at gVCF block splits will be substituted with N’s. + The --gvcf option uses the following default INFO rules: + -i QS:sum,MinDP:min,I16:sum,IDV:max,IMF:max. +
+-i, --info-rules -|TAG:METHOD[,…] +
+ Rules for merging INFO fields (scalars or vectors) or - to disable the + default rules. METHOD is one of sum, avg, min, max, join. + Default is DP:sum,DP4:sum if these fields exist in the input files. + Fields with no specified rule will take the value from the first input file. + The merged QUAL value is currently set to the maximum. This behaviour is + not user controllable at the moment. +
+-l, --file-list FILE +
+ Read file names from FILE, one file name per line. +
+-m, --merge snps|indels|both|all|none|id +
+ The option controls what types of multiallelic records can be created: +
-m none   ..  no new multiallelics, output multiple records instead
+-m snps   ..  allow multiallelic SNP records
+-m indels ..  allow multiallelic indel records
+-m both   ..  both SNP and indel records can be multiallelic
+-m all    ..  SNP records can be merged with indel records
+-m id     ..  merge by ID
+--no-version +
+ see Common Options +
+-o, --output FILE +
+ see Common Options +
+-O, --output-type b|u|z|v +
+ see Common Options +
+-r, --regions chr|chr:pos|chr:from-to|chr:from-[,…] +
+ see Common Options +
+-R, --regions-file file +
+ see Common Options +
+--threads INT +
+ see Common Options +

bcftools mpileup [OPTIONS] -f ref.fa in.bam [in2.bam […]]

Generate VCF or BCF containing genotype likelihoods for one or multiple +alignment (BAM or CRAM) files. This is based on the original +samtools mpileup command (with the -v or -g options) producing +genotype likelihoods in VCF or BCF format, but not the textual pileup +output. The mpileup command was transferred to bcftools in order to +avoid errors resulting from use of incompatible versions of samtools +and bcftools when using in the mpileup+bcftools call pipeline.

Individuals are identified from the SM tags in the @RG header lines. Multiple +individuals can be pooled in one alignment file, also one individual can be +separated into multiple files. If sample identifiers are absent, each input +file is regarded as one sample.

Note that there are two orthogonal ways to specify locations in the +input file; via -r region and -t positions. The +former uses (and requires) an index to do random access while the +latter streams through the file contents filtering out the specified +regions, requiring no index. The two may be used in conjunction. For +example a BED file containing locations of genes in chromosome 20 +could be specified using -r 20 -t chr20.bed, meaning that the +index is used to find chromosome 20 and then it is filtered for the +regions listed in the BED file. Also note that the -r option can be much +slower than -t with many regions and can require more memory when +multiple regions and many alignment files are processed.

Input options

+-6, --illumina1.3+ +
+ Assume the quality is in the Illumina 1.3+ encoding. +
+-A, --count-orphans +
+ Do not skip anomalous read pairs in variant calling. +
+-b, --bam-list FILE +
+ List of input alignment files, one file per line [null] +
+-B, --no-BAQ +
+ Disable probabilistic realignment for the computation of base alignment + quality (BAQ). BAQ is the Phred-scaled probability of a read base being + misaligned. Applying this option greatly helps to reduce false SNPs caused + by misalignments. +
+-C, --adjust-MQ INT +
+ Coefficient for downgrading mapping quality for reads containing + excessive mismatches. Given a read with a phred-scaled probability q of + being generated from the mapped posi- tion, the new mapping quality is + about sqrt((INT-q)/INT)*INT. A zero value disables this functionality; if + enabled, the recommended value for BWA is 50. [0] +
+-d, --max-depth INT +
+ At a position, read maximally INT reads per input file. Note that bcftools + has a minimum value of 8000/n where n is the number of input files given + to mpileup. This means the default is highly likely to be increased. Once + above the cross-sample minimum of 8000 the -d parameter will have an effect. + [250] +
+-E, --redo-BAQ +
+ Recalculate BAQ on the fly, ignore existing BQ tags +
+-f, --fasta-ref FILE +
+ The faidx-indexed reference file in the FASTA format. The file can be + optionally compressed by bgzip. Reference is required by default + unless the --no-reference option is set [null] +
+--no-reference +
+ Do not require the --fasta-ref option. +
+-G, --read-groups FILE +
+ list of read groups to include or exclude if prefixed with "^". + One read group per line. This file can also be used to assign new sample + names to read groups by giving the new sample name as a second + white-space-separated field, like this: "read_group_id new_sample_name". + If the read group name is not unique, also the bam file name can + be included: "read_group_id file_name sample_name". If all + reads from the alignment file should be treated as a single sample, the + asterisk symbol can be used: "* file_name sample_name". Alignments without + a read group ID can be matched with "?". +
    RG_ID_1
+    RG_ID_2  SAMPLE_A
+    RG_ID_3  SAMPLE_A
+    RG_ID_4  SAMPLE_B
+    RG_ID_5  FILE_1.bam  SAMPLE_A
+    RG_ID_6  FILE_2.bam  SAMPLE_A
+    *        FILE_3.bam  SAMPLE_C
+    ?        FILE_3.bam  SAMPLE_D
+-q, -min-MQ INT +
+ Minimum mapping quality for an alignment to be used [0] +
+-Q, --min-BQ INT +
+ Minimum base quality for a base to be considered [13] +
+-r, --regions CHR|CHR:POS|CHR:FROM-TO|CHR:FROM-[,…] +
+ Only generate mpileup output in given regions. Requires the alignment files + to be indexed. If used in conjunction with -l then considers the intersection; + see Common Options +
+-R, --regions-file FILE +
+ As for -r, --regions, but regions read from FILE; + see Common Options +
+--ignore-RG +
+ Ignore RG tags. Treat all reads in one alignment file as one sample. +
+--rf, --incl-flags STR|INT +
+ Required flags: skip reads with mask bits unset [null] +
+--ff, --excl-flags STR|INT +
+ Filter flags: skip reads with mask bits set [UNMAP,SECONDARY,QCFAIL,DUP] +
+-s, --samples LIST +
+ list of sample names. See Common Options +
+-S, --samples-file FILE +
+ file of sample names to include or exclude if prefixed with "^". + One sample per line. This file can also be used to rename samples by giving + the new sample name as a second white-space-separated column, like this: + "old_name new_name". If a sample name contains spaces, the spaces can be + escaped using the backslash character, for example "Not\ a\ good\ sample\ + name". +
+-t, --targets LIST +
+ see Common Options +
+-T, --targets-file FILE +
+ see Common Options +
+-x, --ignore-overlaps +
+ Disable read-pair overlap detection. +

Output options

+-a, --annotate LIST +

+ Comma-separated list of FORMAT and INFO tags to output. (case-insensitive, + the "FORMAT/" prefix is optional, and use "?" to list available annotations + on the command line) [null]: +

*FORMAT/AD* .. Allelic depth (Number=R,Type=Integer)
+*FORMAT/ADF* .. Allelic depths on the forward strand (Number=R,Type=Integer)
+*FORMAT/ADR* .. Allelic depths on the reverse strand (Number=R,Type=Integer)
+*FORMAT/DP* .. Number of high-quality bases (Number=1,Type=Integer)
+*FORMAT/SP* .. Phred-scaled strand bias P-value (Number=1,Type=Integer)
*INFO/AD* .. Total allelic depth (Number=R,Type=Integer)
+*INFO/ADF* .. Total allelic depths on the forward strand (Number=R,Type=Integer)
+*INFO/ADR* .. Total allelic depths on the reverse strand (Number=R,Type=Integer)
*FORMAT/DV* .. Deprecated in favor of FORMAT/AD;
+        Number of high-quality non-reference bases, (Number=1,Type=Integer)
+*FORMAT/DP4* .. Deprecated in favor of FORMAT/ADF and FORMAT/ADR;
+        Number of high-quality ref-forward, ref-reverse,
+        alt-forward and alt-reverse bases (Number=4,Type=Integer)
+*FORMAT/DPR* .. Deprecated in favor of FORMAT/AD;
+        Number of high-quality bases for each observed allele (Number=R,Type=Integer)
+*INFO/DPR* .. Deprecated in favor of INFO/AD;
+        Number of high-quality bases for each observed allele (Number=R,Type=Integer)
+-g, --gvcf INT[,…] +
+ output gVCF blocks of homozygous REF calls, with depth (DP) ranges + specified by the list of integers. For example, passing 5,15 will + group sites into two types of gVCF blocks, the first with minimum + per-sample DP from the interval [5,15) and the latter with minimum + depth 15 or more. In this example, sites with minimum per-sample + depth less than 5 will be printed as separate records, outside of + gVCF blocks. +
+--no-version +
+ see Common Options +
+-o, --output FILE +
+ Write output to FILE, rather than the default of standard output. + (The same short option is used for both --open-prob and --output. If -o's + argument contains any non-digit characters other than a leading + or - + sign, it is interpreted as --output. Usually the filename extension + will take care of this, but to write to an entirely numeric filename use -o + ./123 or --output 123.) +
+-O, --output-type b|u|z|v +
+ see Common Options +
+--threads INT +
+ see Common Options +

Options for SNP/INDEL genotype likelihood computation

+-e, --ext-prob INT +
+ Phred-scaled gap extension sequencing error probability. Reducing INT + leads to longer indels [20] +
+-F, --gap-frac FLOAT +
+ Minimum fraction of gapped reads [0.002] +
+-h, --tandem-qual INT +
+ Coefficient for modeling homopolymer errors. Given an l-long homopolymer + run, the sequencing error of an indel of size s is modeled as INT*s/l [100] +
+-I, --skip-indels +
+ Do not perform INDEL calling +
+-L, --max-idepth INT +
+ Skip INDEL calling if the average per-sample depth is above INT [250] +
+-m, --min-ireads INT +
+ Minimum number gapped reads for indel candidates INT [1] +
+-o, --open-prob INT +
+ Phred-scaled gap open sequencing error probability. Reducing INT leads + to more indel calls. (The same short option is used for both --open-prob + and --output. When -o’s argument contains only an optional + or - sign + followed by the digits 0 to 9, it is interpreted as --open-prob.) [40] +
+-p, --per-sample-mF +
+ Apply -m and -F thresholds per sample to increase sensitivity of calling. + By default both options are applied to reads pooled from all samples. +
+-P, --platforms STR +
+ Comma-delimited list of platforms (determined by @RG-PL) from which + indel candidates are obtained. It is recommended to collect indel + candidates from sequencing technologies that have low indel error rate + such as ILLUMINA [all] +

Examples:

Call SNPs and short INDELs, then mark low quality sites and sites with the read +depth exceeding a limit. (The read depth should be adjusted to about twice the +average read depth as higher read depths usually indicate problematic regions +which are often enriched for artefacts.) One may consider to add -C50 to +mpileup if mapping quality is overestimated for reads containing excessive +mismatches. Applying this option usually helps for BWA-backtrack alignments, +but may not other aligners.

    bcftools mpileup -Ou -f ref.fa aln.bam | \
+    bcftools call -Ou -mv | \
+    bcftools filter -s LowQual -e '%QUAL<20 || DP>100' > var.flt.vcf

bcftools norm [OPTIONS] file.vcf.gz

Left-align and normalize indels, check if REF alleles match the reference, +split multiallelic sites into multiple rows; recover multiallelics from +multiple rows. Left-alignment and normalization will only be applied if +the --fasta-ref option is supplied.

+-c, --check-ref e|w|x|s +
+ what to do when incorrect or missing REF allele is encountered: + exit (e), warn (w), exclude (x), or set/fix (s) bad sites. + The w option can be combined with x and s. Note that s + can swap alleles and will update genotypes (GT) and AC counts, + but will not attempt to fix PL or other fields. +
+-d, --rm-dup snps|indels|both|all|none +
+ If a record is present multiple times, output only the first instance, + see --collapse in Common Options. + Requires -a, --allow-overlaps. +
+-D, --remove-duplicates +
+ If a record is present in multiple files, output only the first instance. + Alias for -d none. Requires -a, --allow-overlaps. +
+-f, --fasta-ref FILE +
+ reference sequence. Supplying this option will turn on left-alignment + and normalization, however, see also the --do-not-normalize + option below. +
+-m, --multiallelics -|+[snps|indels|both|any] +
+ split multiallelic sites into biallelic records (-) or join + biallelic sites into multiallelic records (+). An optional type string + can follow which controls variant types which should be split or merged + together: If only SNP records should be split or merged, specify snps; if + both SNPs and indels should be merged separately into two records, specify + both; if SNPs and indels should be merged into a single record, specify + any. +
+--no-version +
+ see Common Options +
+-N, --do-not-normalize +
+ the -c s option can be used to fix or set the REF allele from the + reference -f. The -N option will not turn on indel normalisation + as the -f option normally implies +
+-o, --output FILE +
+ see Common Options +
+-O, --output-type b|u|z|v +
+ see Common Options +
+-r, --regions chr|chr:pos|chr:from-to|chr:from-[,…] +
+ see Common Options +
+-R, --regions-file file +
+ see Common Options +
+-s, --strict-filter +
+ when merging (-m+), merged site is PASS only if all sites being merged PASS +
+-t, --targets LIST +
+ see Common Options +
+-T, --targets-file FILE +
+ see Common Options +
+--threads INT +
+ see Common Options +
+-w, --site-win INT +
+ maximum distance between two records to consider when locally + sorting variants which changed position during the realignment +

bcftools [plugin NAME|+NAME] [OPTIONS] FILE — [PLUGIN OPTIONS]

A common framework for various utilities. The plugins can be used +the same way as normal commands only their name is prefixed with "+". +Most plugins accept two types of parameters: general options shared by all +plugins followed by a separator, and a list of plugin-specific options. There +are some exceptions to this rule, some plugins do not accept the common +options and implement their own parameters. Therefore please pay attention to +the usage examples that each plugin comes with.

VCF input options:

+-e, --exclude EXPRESSION +
+ exclude sites for which EXPRESSION is true. For valid expressions see + EXPRESSIONS. +
+-i, --include EXPRESSION +
+ include only sites for which EXPRESSION is true. For valid expressions see + EXPRESSIONS. +
+-r, --regions chr|chr:pos|chr:from-to|chr:from-[,…] +
+ see Common Options +
+-R, --regions-file file +
+ see Common Options +
+-t, --targets chr|chr:pos|chr:from-to|chr:from-[,…] +
+ see Common Options +
+-T, --targets-file file +
+ see Common Options +

VCF output options:

+--no-version +
+ see Common Options +
+-o, --output FILE +
+ see Common Options +
+-O, --output-type b|u|z|v +
+ see Common Options +
+--threads INT +
+ see Common Options +

Plugin options:

+-h, --help +
+ list plugin’s options +
+-l, --list-plugins +

+ List all available plugins. +

By default, appropriate system directories are searched for installed plugins. + You can override this by setting the BCFTOOLS_PLUGINS environment variable + to a colon-separated list of directories to search. + If BCFTOOLS_PLUGINS begins with a colon, ends with a colon, or contains + adjacent colons, the system directories are also searched at that position + in the list of directories.

+-v, --verbose +
+ print debugging information to debug plugin failure +
+-V, --version +
+ print version string and exit +

List of plugins coming with the distribution:

+GTisec +
+ count genotype intersections across all possible sample subsets in a vcf file +
+GTsubset +
+ output only sites where the requested samples all exclusively share a genotype +
+ad-bias +
+ find positions with wildly varying ALT allele frequency (Fisher test on FMT/AD) +
+af-dist +
+ collect AF deviation stats and GT probability distribution given AF and assuming HWE +
+color-chrs +
+ color shared chromosomal segments, requires trio VCF with phased GTs +
+counts +
+ a minimal plugin which counts number of SNPs, Indels, and total number of sites. +
+dosage +
+ print genotype dosage. By default the plugin searches for PL, GL and GT, in + that order. +
+fill-AN-AC +
+ fill INFO fields AN and AC. +
+fill-from-fasta +
+ fill INFO or REF field based on values in a fasta file +
+fill-tags +
+ set INFO tags AF, AN, AC, NS, AC_Hom, AC_Het, AC_Hemi +
+fix-ploidy +
+ sets correct ploidy +
+fixref +
+ determine and fix strand orientation +
+frameshifts +
+ annotate frameshift indels +
+guess-ploidy +
+ determine sample sex by checking genotype likelihoods (GL,PL) or genotypes (GT) + in the non-PAR region of chrX. +
+impute-info +
+ add imputation information metrics to the INFO field based on selected FORMAT tags +
+mendelian +
+ count Mendelian consistent / inconsistent genotypes. +
+missing2ref +
+ sets missing genotypes ("./.") to ref allele ("0/0" or "0|0") +
+setGT +
+ general tool to set genotypes according to rules requested by the user +
+tag2tag +
+ convert between similar tags, such as GL and GP +
+trio-switch-rate +
+ calculate phase switch rate in trio samples, children samples must have phased GTs. +

Examples:

# List options common to all plugins
+bcftools plugin
+
+# List available plugins
+bcftools plugin -l
+
+# Run a plugin
+bcftools plugin counts in.vcf
+
+# Run a plugin using the abbreviated "+" notation
+bcftools +counts in.vcf
+
+# The input VCF can be streamed just like in other commands
+cat in.vcf | bcftools +counts
+
+# Print usage information of plugin "dosage"
+bcftools +dosage -h
+
+# Replace missing genotypes with 0/0
+bcftools +missing2ref in.vcf
+
+# Replace missing genotypes with 0|0
+bcftools +missing2ref in.vcf -- -p

Plugins troubleshooting:

Things to check if your plugin does not show up in the bcftools plugin -l output:

  • +Run with the -v option for verbose output: bcftools plugin -lv +
  • +Does the environment variable BCFTOOLS_PLUGINS include the correct path? +

Plugins API:

// Short description used by 'bcftools plugin -l'
+const char *about(void);
+
+// Longer description used by 'bcftools +name -h'
+const char *usage(void);
+
+// Called once at startup, allows initialization of local variables.
+// Return 1 to suppress normal VCF/BCF header output, -1 on critical
+// errors, 0 otherwise.
+int init(int argc, char **argv, bcf_hdr_t *in_hdr, bcf_hdr_t *out_hdr);
+
+// Called for each VCF record, return NULL to suppress the output
+bcf1_t *process(bcf1_t *rec);
+
+// Called after all lines have been processed to clean up
+void destroy(void);

bcftools polysomy [OPTIONS] file.vcf.gz

Detect number of chromosomal copies in VCFs annotates with the Illumina’s +B-allele frequency (BAF) values. Note that this command is not compiled +in by default, see the section Optional Compilation with GSL in the INSTALL +file for help.

General options:

+-o, --output-dir path +
+ output directory +
+-r, --regions chr|chr:pos|chr:from-to|chr:from-[,…] +
+ see Common Options +
+-R, --regions-file file +
+ see Common Options +
+-s, --sample string +
+ sample name +
+-t, --targets LIST +
+ see Common Options +
+-T, --targets-file FILE +
+ see Common Options +
+-v, --verbose +
+ verbose debugging output which gives hints about the thresholds and decisions made + by the program. Note that the exact output can change between versions. +

Algorithm options:

+-b, --peak-size float +
+ the minimum peak size considered as a good match can be from the interval [0,1] + where larger is stricter +
+-c, --cn-penalty float +
+ a penalty for increasing copy number state. How this works: multiple peaks + are always a better fit than a single peak, therefore the program prefers + a single peak (normal copy number) unless the absolute deviation of the + multiple peaks fit is significantly smaller. Here the meaning of + "significant" is given by the float from the interval [0,1] where + larger is stricter. +
+-f, --fit-th float +
+ threshold for goodness of fit (normalized absolute deviation), smaller is stricter +
+-i, --include-aa +
+ include also the AA peak in CN2 and CN3 evaluation. This usually requires increasing -f. +
+-m, --min-fraction float +
+ minimum distinguishable fraction of aberrant cells. The experience shows that trustworthy + are estimates of 20% and more. +
+-p, --peak-symmetry float +
+ a heuristics to filter failed fits where the expected peak symmetry is violated. + The float is from the interval [0,1] and larger is stricter +

bcftools query [OPTIONS] file.vcf.gz [file.vcf.gz […]]

Extracts fields from VCF or BCF files and outputs them in user-defined format.

+-c, --collapse snps|indels|both|all|some|none +
+ see Common Options +
+-e, --exclude EXPRESSION +
+ exclude sites for which EXPRESSION is true. For valid expressions see + EXPRESSIONS. +
+-f, --format FORMAT +
+ learn by example, see below +
+-H, --print-header +
+ print header +
+-i, --include EXPRESSION +
+ include only sites for which EXPRESSION is true. For valid expressions see + EXPRESSIONS. +
+-l, --list-samples +
+ list sample names and exit +
+-o, --output FILE +
+ see Common Options +
+-r, --regions chr|chr:pos|chr:from-to|chr:from-[,…] +
+ see Common Options +
+-R, --regions-file file +
+ see Common Options +
+-s, --samples LIST +
+ see Common Options +
+-S, --samples-file FILE +
+ see Common Options +
+-t, --targets chr|chr:pos|chr:from-to|chr:from-[,…] +
+ see Common Options +
+-T, --targets-file file +
+ see Common Options +
+-u, --allow-undef-tags +
+ do not throw an error if there are undefined tags in the format string, + print "." instead +
+-v, --vcf-list FILE +
+ process multiple VCFs listed in the file +

Format:

%CHROM          The CHROM column (similarly also other columns: POS, ID, REF, ALT, QUAL, FILTER)
+%INFO/TAG       Any tag in the INFO column
+%TYPE           Variant type (REF, SNP, MNP, INDEL, BND, OTHER)
+%MASK           Indicates presence of the site in other files (with multiple files)
+%TAG{INT}       Curly brackets to subscript vectors (0-based)
+%FIRST_ALT      Alias for %ALT{0}
+[]              Format fields must be enclosed in brackets to loop over all samples
+%GT             Genotype (e.g. 0/1)
+%TBCSQ          Translated FORMAT/BCSQ. See the csq command above for explanation and examples.
+%TGT            Translated genotype (e.g. C/A)
+%IUPACGT        Genotype translated to IUPAC ambiguity codes (e.g. M instead of C/A)
+%LINE           Prints the whole line
+%SAMPLE         Sample name
+%POS0           POS in 0-based coordinates
+%END            End position of the REF allele
+%END0           End position of the REF allele in 0-based cordinates
+\n              new line
+\t              tab character
Everything else is printed verbatim.

Examples:

# Print chromosome, position, ref allele and the first alternate allele
+bcftools query -f '%CHROM  %POS  %REF  %ALT{0}\n' file.vcf.gz
# Similar to above, but use tabs instead of spaces, add sample name and genotype
+bcftools query -f '%CHROM\t%POS\t%REF\t%ALT[\t%SAMPLE=%GT]\n' file.vcf.gz
# Print FORMAT/GT fields followed by FORMAT/GT fields
+bcftools query -f 'GQ:[ %GQ] \t GT:[ %GT]\n' file.vcf
# Make a BED file: chr, pos (0-based), end pos (1-based), id
+bcftools query -f'%CHROM\t%POS0\t%END\t%ID\n' file.bcf

bcftools reheader [OPTIONS] file.vcf.gz

Modify header of VCF/BCF files, change sample names.

+-h, --header FILE +
+ new VCF header +
+-o, --output FILE +
+ see Common Options +
+-s, --samples FILE +
+ new sample names, one name per line, in the same order as they appear + in the VCF file. Alternatively, only samples which need to be renamed + can be listed as "old_name new_name\n" pairs separated by whitespaces, + each on a separate line. If a sample name contains spaces, the + spaces can be escaped using the backslash character, for example + "Not\ a\ good\ sample\ name". +

bcftools roh [OPTIONS] file.vcf.gz

A program for detecting runs of homo/autozygosity. Only bi-allelic sites +are considered.

The HMM model:

Notation:
+  D  = Data, AZ = autozygosity, HW = Hardy-Weinberg (non-autozygosity),
+  f  = non-ref allele frequency
+
+Emission probabilities:
+  oAZ = P_i(D|AZ) = (1-f)*P(D|RR) + f*P(D|AA)
+  oHW = P_i(D|HW) = (1-f)^2 * P(D|RR) + f^2 * P(D|AA) + 2*f*(1-f)*P(D|RA)
+
+Transition probabilities:
+  tAZ = P(AZ|HW)  .. from HW to AZ, the -a parameter
+  tHW = P(HW|AZ)  .. from AZ to HW, the -H parameter
+
+  ci  = P_i(C)  .. probability of cross-over at site i, from genetic map
+  AZi = P_i(AZ) .. probability of site i being AZ/non-AZ, scaled so that AZi+HWi = 1
+  HWi = P_i(HW)
+
+  P_{i+1}(AZ) = oAZ * max[(1 - tAZ * ci) * AZ{i-1} , tAZ * ci * (1-AZ{i-1})]
+  P_{i+1}(HW) = oHW * max[(1 - tHW * ci) * (1-AZ{i-1}) , tHW * ci * AZ{i-1}]

General Options:

+--AF-dflt FLOAT +
+ in case allele frequency is not known, use the FLOAT. By default, sites where + allele frequency cannot be determined, or is 0, are skipped. +
+--AF-tag TAG +
+ use the specified INFO tag TAG as an allele frequency estimate + instead of the default AC and AN tags. Sites which do not have TAG + will be skipped. +
+--AF-file FILE +
+ Read allele frequencies from a tab-delimited file containing + the columns: CHROM\tPOS\tREF,ALT\tAF. The file can be compressed with + bgzip and indexed with tabix -s1 -b2 -e2. Sites which are not present in + the FILE or have different reference or alternate allele will be skipped. + Note that such a file can be easily created from a VCF using: +
    bcftools query -f'%CHROM\t%POS\t%REF,%ALT\t%INFO/TAG\n' file.vcf | bgzip -c > freqs.tab.gz
+-b, --buffer-size INT[,INT] +
+ when the entire many-sample file cannot fit into memory, a sliding + buffer approach can be used. The first value is the number of sites + to keep in memory. If negative, it is interpreted as the maximum + memory to use, in MB. The second, optional, value sets the number + of overlapping sites. The default overlap is set to roughly 1% of + the buffer size. +
+-e, --estimate-AF FILE +
+ estimate the allele frequency by recalculating INFO/AC and INFO/AN on + the fly, using the specified TAG which can be either FORMAT/GT ("GT") + or FORMAT/PL ("PL"). If TAG is not given, "GT" is assumed. Either all + samples ("-") or samples listed in FILE will be included. For example, + use "PL,-" to estimate AF from FORMAT/PL of all samples. + If neither -e nor the other --AF-… options are given, the allele frequency is + estimated from AC and AN counts which are already present in the INFO field. +
+-G, --GTs-only FLOAT +
+ use genotypes (FORMAT/GT fields) ignoring genotype likelihoods (FORMAT/PL), + setting PL of unseen genotypes to FLOAT. Safe value to use is 30 to + account for GT errors. +
+-I, --skip-indels +
+ skip indels as their genotypes are usually enriched for errors +
+-m, --genetic-map FILE +
+ genetic map in the format required also by IMPUTE2. Only the first and + third column are used (position and Genetic_Map(cM)). The FILE can + chromosome name. +
+-M, --rec-rate FLOAT +
+ constant recombination rate per bp. In combination with --genetic-map, + the --rec-rate parameter is interpreted differently, as FLOAT-fold increase of + transition probabilities, which allows the model to become more sensitive + yet still account for recombination hotspots. Note that also the range + of the values is therefore different in both cases: normally the + parameter will be in the range (1e-3,1e-9) but with --genetic-map + it will be in the range (10,1000). +
+-o, --output FILE +
+ Write output to the FILE, by default the output is printed on stdout +
+-O, --output-type s|r[z] +
+ Generate per-site output (s) or per-region output (r). By default + both types are printed and the output is uncompressed. Add z for + a compressed output. +
+-r, --regions chr|chr:pos|chr:from-to|chr:from-[,…] +
+ see Common Options +
+-R, --regions-file file +
+ see Common Options +
+-s, --samples LIST +
+ see Common Options +
+-S, --samples-file FILE +
+ see Common Options +
+-t, --targets chr|chr:pos|chr:from-to|chr:from-[,…] +
+ see Common Options +
+-T, --targets-file file +
+ see Common Options +

HMM Options:

+-a, --hw-to-az FLOAT +
+ P(AZ|HW) transition probability from AZ (autozygous) to HW (Hardy-Weinberg) state +
+-H, --az-to-hw FLOAT +
+ P(HW|AZ) transition probability from HW to AZ state +
+-V, --viterbi-training FLOAT +
+ estimate HMM parameters using Baum-Welch algorithm, using the convergence threshold + FLOAT, e.g. 1e-10 (experimental) +

bcftools stats [OPTIONS] A.vcf.gz [B.vcf.gz]

Parses VCF or BCF and produces text file stats which is suitable for machine +processing and can be plotted using plot-vcfstats. When two files are given, +the program generates separate stats for intersection and the complements. By +default only sites are compared, -s/-S must given to include also sample +columns. +When one VCF file is specified on the command line, then stats by non-reference allele +frequency, depth distribution, stats by quality and per-sample counts, singleton stats, +etc. are printed. +When two VCF files are given, then stats such as concordance (Genotype concordance by +non-reference allele frequency, Genotype concordance by sample, Non-Reference Discordance) +and correlation are also printed. Per-site discordance (PSD) is also printed in --verbose mode.

+--af-bins LIST|FILE +
+ comma separated list of allele frequency bins (e.g. 0.1,0.5,1) + or a file listing the allele frequency bins one per line (e.g. 0.1\n0.5\n1) +
+--af-tag TAG +
+ allele frequency INFO tag to use for binning. By default the allele frequency is + estimated from AC/AN, if available, or directly from the genotypes (GT) if not. +
+-1, --1st-allele-only +
+ consider only the 1st alternate allele at multiallelic sites +
+-c, --collapse snps|indels|both|all|some|none +
+ see Common Options +
+-d, --depth INT,INT,INT +
+ ranges of depth distribution: min, max, and size of the bin +
+--debug +
+ produce verbose per-site and per-sample output +
+-e, --exclude EXPRESSION +
+ exclude sites for which EXPRESSION is true. For valid expressions see + EXPRESSIONS. +
+-E, --exons file.gz +
+ tab-delimited file with exons for indel frameshifts statistics. The columns + of the file are CHR, FROM, TO, with 1-based, inclusive, positions. The file + is BGZF-compressed and indexed with tabix +
    tabix -s1 -b2 -e3 file.gz
+-f, --apply-filters LIST +
+ see Common Options +
+-F, --fasta-ref ref.fa +
+ faidx indexed reference sequence file to determine INDEL context +
+-i, --include EXPRESSION +
+ include only sites for which EXPRESSION is true. For valid expressions see + EXPRESSIONS. +
+-I, --split-by-ID +
+ collect stats separately for sites which have the ID column set ("known + sites") or which do not have the ID column set ("novel sites"). +
+-r, --regions chr|chr:pos|chr:from-to|chr:from-[,…] +
+ see Common Options +
+-R, --regions-file file +
+ see Common Options +
+-s, --samples LIST +
+ see Common Options +
+-S, --samples-file FILE +
+ see Common Options +
+-t, --targets chr|chr:pos|chr:from-to|chr:from-[,…] +
+ see Common Options +
+-T, --targets-file file +
+ see Common Options +
+-u, --user-tstv <TAG[:min:max:n]> +
+ collect Ts/Tv stats for any tag using the given binning [0:1:100] +
+-v, --verbose +
+ produce verbose per-site and per-sample output +

bcftools view [OPTIONS] file.vcf.gz [REGION […]]

View, subset and filter VCF or BCF files by position and filtering expression. +Convert between VCF and BCF. Former bcftools subset.

Output options

+-G, --drop-genotypes +
+ drop individual genotype information (after subsetting if -s option is set) +
+-h, --header-only +
+ output the VCF header only +
+-H, --no-header +
+ suppress the header in VCF output +
+-l, --compression-level [0-9] +
+ compression level. 0 stands for uncompressed, 1 for best speed and 9 for + best compression. +
+--no-version +
+ see Common Options +
+-O, --output-type b|u|z|v +
+ see Common Options +

-o, --output-file FILE: + output file name. If not present, the default is to print to standard output (stdout).

+-r, --regions chr|chr:pos|chr:from-to|chr:from-[,…] +
+ see Common Options +
+-R, --regions-file file +
+ see Common Options +
+-t, --targets chr|chr:pos|chr:from-to|chr:from-[,…] +
+ see Common Options +
+-T, --targets-file file +
+ see Common Options +
+--threads INT +
+ see Common Options +

Subset options:

+-a, --trim-alt-alleles +
+ trim alternate alleles not seen in subset. Type A, G and R INFO and FORMAT + fields will also be trimmed +
+--force-samples +
+ only warn about unknown subset samples +
+-I, --no-update +
+ do not (re)calculate INFO fields for the subset (currently INFO/AC and INFO/AN) +
+-s, --samples LIST +
+ see Common Options +
+-S, --samples-file FILE +
+ see Common Options +

Filter options:

Note that filter options below dealing with counting the number of alleles +will, for speed, first check for the values of AC and AN in the INFO column to +avoid parsing all the genotype (FORMAT/GT) fields in the VCF. This means +that a filter like --min-af 0.1 will be based ‘AC/AN’ where AC and AN come +from either INFO/AC and INFO/AN if available or FORMAT/GT if not. It will not +filter on another field like INFO/AF. The --include and --exclude filter +expressions should instead be used to explicitly filter based on fields in +the INFO column, e.g. --exclude AF<0.1.

+-c, --min-ac INT[:nref|:alt1|:minor|:major|:'nonmajor'] +
+ minimum allele count (INFO/AC) of sites to be printed. + Specifying the type of allele is optional and can be set to + non-reference (nref, the default), 1st alternate (alt1), the least + frequent (minor), the most frequent (major) or sum of all but the + most frequent (nonmajor) alleles. +
+-C, --max-ac INT[:nref|:alt1|:minor|:'major'|:'nonmajor'] +
+ maximum allele count (INFO/AC) of sites to be printed. + Specifying the type of allele is optional and can be set to + non-reference (nref, the default), 1st alternate (alt1), the least + frequent (minor), the most frequent (major) or sum of all but the + most frequent (nonmajor) alleles. +
+-e, --exclude EXPRESSION +
+ exclude sites for which EXPRESSION is true. For valid expressions see + EXPRESSIONS. +
+-f, --apply-filters LIST +
+ see Common Options +
+-g, --genotype [^][hom|het|miss] +
+ include only sites with one or more homozygous (hom), heterozygous + (het) or missing (miss) genotypes. When prefixed with ^, the logic + is reversed; thus ^het excludes sites with heterozygous genotypes. +
+-i, --include EXPRESSION +
+ include sites for which EXPRESSION is true. For valid expressions see + EXPRESSIONS. +
+-k, --known +
+ print known sites only (ID column is not ".") +
+-m, --min-alleles INT +
+ print sites with at least INT alleles listed in REF and ALT columns +
+-M, --max-alleles INT +
+ print sites with at most INT alleles listed in REF and ALT columns. + Use -m2 -M2 -v snps to only view biallelic SNPs. +
+-n, --novel +
+ print novel sites only (ID column is ".") +
+-p, --phased +
+ print sites where all samples are phased. Haploid genotypes are + considered phased. Missing genotypes considered unphased unless the + phased bit is set. +
+-P, --exclude-phased +
+ exclude sites where all samples are phased +
+-q, --min-af FLOAT[:nref|:alt1|:minor|:major|:nonmajor] +
+ minimum allele frequency (INFO/AC / INFO/AN) of sites to be printed. + Specifying the type of allele is optional and can be set to + non-reference (nref, the default), 1st alternate (alt1), the least + frequent (minor), the most frequent (major) or sum of all but the + most frequent (nonmajor) alleles. +
+-Q, --max-af FLOAT[:nref|:alt1|:minor|:major|:nonmajor] +
+ maximum allele frequency (INFO/AC / INFO/AN) of sites to be printed. + Specifying the type of allele is optional and can be set to + non-reference (nref, the default), 1st alternate (alt1), the least + frequent (minor), the most frequent (major) or sum of all but the + most frequent (nonmajor) alleles. +
+-u, --uncalled +
+ print sites without a called genotype +
+-U, --exclude-uncalled +
+ exclude sites without a called genotype +
+-v, --types snps|indels|mnps|other +
+ comma-separated list of variant types to select. Site is selected if + any of the ALT alleles is of the type requested. Types are determined + by comparing the REF and ALT alleles in the VCF record not INFO tags + like INFO/INDEL or INFO/VT. Use --include to select based on INFO + tags. +
+-V, --exclude-types snps|indels|mnps|ref|bnd|other +
+ comma-separated list of variant types to exclude. Site is excluded if + any of the ALT alleles is of the type requested. Types are determined + by comparing the REF and ALT alleles in the VCF record not INFO tags + like INFO/INDEL or INFO/VT. Use --exclude to exclude based on INFO tags. +
+-x, --private +
+ print sites where only the subset samples carry an non-reference allele. + Requires --samples or --samples-file. +
+-X, --exclude-private +
+ exclude sites where only the subset samples carry an non-reference allele +

bcftools help [COMMAND] | bcftools --help [COMMAND]

Display a brief usage message listing the bcftools commands available. +If the name of a command is also given, e.g., bcftools help view, the detailed +usage message for that particular command is displayed.

bcftools [--version|-v]

Display the version numbers and copyright information for bcftools and the +important libraries used by bcftools.

bcftools [--version-only]

Display the full bcftools version number in a machine-readable format.

EXPRESSIONS

These filtering expressions are accepted by most of the commands.

Valid expressions may contain:

  • +numerical constants, string constants, file names +

    1, 1.0, 1e-4
+"String"
+@file_name

  • +arithmetic operators +

    +,*,-,/

  • +comparison operators +

    == (same as =), >, >=, <=, <, !=

  • +regex operators "~" and its negation "!~". The expressions are case sensitive unless "/i" is added. +

    INFO/HAYSTACK ~ "needle"
+INFO/HAYSTACK ~ "NEEDless/i"

  • +parentheses +

    (, )

  • +logical operators +

    && (same as &), ||,  |

  • +INFO tags, FORMAT tags, column names +

    INFO/DP or DP
+FORMAT/DV, FMT/DV, or DV
+FILTER, QUAL, ID, POS, REF, ALT[0]

  • +1 (or 0) to test the presence (or absence) of a flag +

    FlagA=1 && FlagB=0

  • +"." to test missing values +

    DP=".", DP!=".", ALT="."

  • +missing genotypes can be matched regardless of phase and ploidy (".|.", "./.", ".") +using these expressions +

    GT~"\.", GT!~"\."

  • +missing genotypes can be matched including the phase and ploidy (".|.", "./.", ".") +using these expressions +

    GT=".|.", GT="./.", GT="."

  • +TYPE for variant type in REF,ALT columns (indel,snp,mnp,ref,bnd,other). Use the regex +operator "\~" to require at least one allele of the given type or the equal sign "=" +to require that all alleles are of the given type. Compare +

    TYPE="snp"
+TYPE~"snp"
+TYPE!="snp"
+TYPE!~"snp"

  • +array subscripts, "*" for any field +

    (DP4[0]+DP4[1])/(DP4[2]+DP4[3]) > 0.3
+DP4[*] == 0
+CSQ[*] ~ "missense_variant.*deleterious"

  • +function on FORMAT tags (over samples) and INFO tags (over vector fields) +

    MAX, MIN, AVG, SUM, STRLEN, ABS

  • +variables calculated on the fly if not present: number of alternate alleles; +number of samples; count of alternate alleles; minor allele count (similar to +AC but is always smaller than 0.5); frequency of alternate alleles (AF=AC/AN); +frequency of minor alleles (MAF=MAC/AN); number of alleles in called genotypes +

    N_ALT, N_SAMPLES, AC, MAC, AF, MAF, AN

Notes:

  • +String comparisons and regular expressions are case-insensitive +
  • +If the subscript "*" is used in regular expression search, the +whole field is treated as one string. For example, the regex STR[*]~"B,C" will be +true for the string vector INFO/STR=AB,CD. +
  • +Variables and function names are case-insensitive, but not tag names. For example, +"qual" can be used instead of "QUAL", "strlen()" instead of "STRLEN()" , but +not "dp" instead of "DP". +

Examples:

MIN(DV)>5
MIN(DV/DP)>0.3
MIN(DP)>10 & MIN(DV)>3
FMT/DP>10  & FMT/GQ>10 .. both conditions must be satisfied within one sample
FMT/DP>10 && FMT/GQ>10 .. the conditions can be satisfied in different samples
QUAL>10 |  FMT/GQ>10   .. selects only GQ>10 samples
QUAL>10 || FMT/GQ>10   .. selects all samples at QUAL>10 sites
TYPE="snp" && QUAL>=10 && (DP4[2]+DP4[3] > 2)
MIN(DP)>35 && AVG(GQ)>50
ID=@file       .. selects lines with ID present in the file
ID!=@~/file    .. skip lines with ID present in the ~/file
MAF[0]<0.05    .. select rare variants at 5% cutoff
POS>=100   .. restrict your range query, e.g. 20:100-200 to strictly sites with POS in that range.

Shell expansion:

Note that expressions must often be quoted because some characters +have special meaning in the shell. +An example of expression enclosed in single quotes which cause +that the whole expression is passed to the program as intended:

bcftools view -i '%ID!="." & MAF[0]<0.01'

Please refer to the documentation of your shell for details.

SCRIPTS AND OPTIONS

plot-vcfstats [OPTIONS] file.vchk […]

Script for processing output of bcftools stats. It can merge +results from multiple outputs (useful when running the stats for each +chromosome separately), plots graphs and creates a PDF presentation.

+-m, --merge +
+ Merge vcfstats files to STDOUT, skip plotting. +
+-p, --prefix DIR +
+ The output directory. This directory will be created if it does not exist. +
+-P, --no-PDF +
+ Skip the PDF creation step. +
+-r, --rasterize +
+ Rasterize PDF images for faster rendering. +
+-s, --sample-names +
+ Use sample names for xticks rather than numeric IDs. +
+-t, --title STRING +
+ Identify files by these titles in plots. The option can be given multiple + times, for each ID in the bcftools stats output. If not + present, the script will use abbreviated source file names for the titles. +
+-T, --main-title STRING +
+ Main title for the PDF. +

PERFORMANCE

HTSlib was designed with BCF format in mind. When parsing VCF files, all records +are internally converted into BCF representation. Simple operations, like removing +a single column from a VCF file, can be therefore done much faster with standard +UNIX commands, such as awk or cut. +Therefore it is recommended to use BCF as input/output format whenever possible to avoid +large overhead of the VCF → BCF → VCF conversion.

BUGS

Please report any bugs you encounter on the github website: http://github.com/samtools/bcftools

AUTHORS

Heng Li from the Sanger Institute wrote the original C version of htslib, +samtools and bcftools. Bob Handsaker from the Broad Institute implemented the +BGZF library. Petr Danecek, Shane McCarthy and John Marshall are maintaining +and further developing bcftools. Many other people contributed to the program +and to the file format specifications, both directly and indirectly by +providing patches, testing and reporting bugs. We thank them all.

RESOURCES

BCFtools GitHub website: http://github.com/samtools/bcftools

Samtools GitHub website: http://github.com/samtools/samtools

HTSlib GitHub website: http://github.com/samtools/htslib

File format specifications: http://samtools.github.io/hts-specs

BCFtools documentation: http://samtools.github.io/bcftools

BCFtools wiki page: https://github.com/samtools/bcftools/wiki

COPYING

The MIT/Expat License or GPL License, see the LICENSE document for details. +Copyright (c) Genome Research Ltd.

diff --git a/doc/bcftools.txt b/doc/bcftools.txt new file mode 100644 index 0000000..e625665 --- /dev/null +++ b/doc/bcftools.txt @@ -0,0 +1,2810 @@ +// bcftools.txt -- asciidoc template for the bcftools man page and html. +// +// Please do not modify bcftools.1 or bcftools.html directly, +// edit this file and convert using the following commands: +// +// make docs +// +// or +// +// a2x --doctype manpage --format manpage bcftools.txt +// a2x --doctype manpage --format xhtml bcftools.txt +// +// Contributions are welcome, simply edit this file and send +// a pull request or email the modified file directly. +// + +bcftools(1) +=========== +:doctype: manpage + + +NAME +---- +bcftools - utilities for variant calling and manipulating VCFs and BCFs. + + +SYNOPSIS +-------- +*bcftools* [--version|--version-only] [--help] ['COMMAND'] ['OPTIONS'] + + +DESCRIPTION +----------- +BCFtools is a set of utilities that manipulate variant calls in the Variant +Call Format (VCF) and its binary counterpart BCF. All commands work +transparently with both VCFs and BCFs, both uncompressed and BGZF-compressed. + +Most commands accept VCF, bgzipped VCF and BCF with filetype detected +automatically even when streaming from a pipe. Indexed VCF and BCF +will work in all situations. Un-indexed VCF and BCF and streams will +work in most, but not all situations. In general, whenever multiple VCFs are +read simultaneously, they must be indexed and therefore also compressed. + +BCFtools is designed to work on a stream. It regards an input file "-" as the +standard input (stdin) and outputs to the standard output (stdout). Several +commands can thus be combined with Unix pipes. + + +=== VERSION +This manual page was last updated *{date}* and refers to bcftools git version *{version}*. + +=== BCF1 +The BCF1 format output by versions of samtools \<= 0.1.19 is *not* +compatible with this version of bcftools. To read BCF1 files one can use +the view command from old versions of bcftools packaged with samtools +versions \<= 0.1.19 to convert to VCF, which can then be read by +this version of bcftools. +---- + samtools-0.1.19/bcftools/bcftools view file.bcf1 | bcftools view +---- + + +=== VARIANT CALLING +See 'bcftools call' for variant calling from the output of the +'samtools mpileup' command. In versions of samtools \<= 0.1.19 calling was +done with 'bcftools view'. Users are now required to choose between the old +samtools calling model ('-c/--consensus-caller') and the new multiallelic +calling model ('-m/--multiallelic-caller'). The multiallelic calling model +is recommended for most tasks. + + +LIST OF COMMANDS +---------------- +For a full list of available commands, run *bcftools* without arguments. For a full +list of available options, run *bcftools* 'COMMAND' without arguments. + +- *<>* .. edit VCF files, add or remove annotations +- *<>* .. SNP/indel calling (former "view") +- *<>* .. Copy Number Variation caller +- *<>* .. concatenate VCF/BCF files from the same set of samples +- *<>* .. create consensus sequence by applying VCF variants +- *<>* .. convert VCF/BCF to other formats and back +- *<>* .. haplotype aware consequence caller +- *<>* .. filter VCF/BCF files using fixed thresholds +- *<>* .. check sample concordance, detect sample swaps and contamination +- *<>* .. index VCF/BCF +- *<>* .. intersections of VCF/BCF files +- *<>* .. merge VCF/BCF files files from non-overlapping sample sets +- *<>* .. multi-way pileup producing genotype likelihoods +- *<>* .. normalize indels +- *<>* .. run user-defined plugin +- *<>* .. detect contaminations and whole-chromosome aberrations +- *<>* .. transform VCF/BCF into user-defined formats +- *<>* .. modify VCF/BCF header, change sample names +- *<>* .. identify runs of homo/auto-zygosity +- *<>* .. produce VCF/BCF stats (former vcfcheck) +- *<>* .. subset, filter and convert VCF and BCF files + + +LIST OF SCRIPTS +--------------- +Some helper scripts are bundled with the bcftools code. + +- *<>* .. plots the output of *<>* + + +COMMANDS AND OPTIONS +-------------------- + +[[common_options]] +=== Common Options + +The following options are common to many bcftools commands. See usage for +specific commands to see if they apply. + +'FILE':: + Files can be both VCF or BCF, uncompressed or BGZF-compressed. The file "-" + is interpreted as standard input. Some tools may require tabix- or + CSI-indexed files. + +*-c, --collapse* 'snps'|'indels'|'both'|'all'|'some'|'none'|'id':: + Controls how to treat records with duplicate positions and defines compatible + records across multiple input files. Here by "compatible" we mean records which + should be considered as identical by the tools. For example, when performing + line intersections, the desire may be to consider as identical all sites with + matching positions (*bcftools isec -c* 'all'), or only sites with matching variant + type (*bcftools isec -c* 'snps'{nbsp} *-c* 'indels'), or only sites with all alleles + identical (*bcftools isec -c* 'none'). + + + 'none';; + only records with identical REF and ALT alleles are compatible + + 'some';; + only records where some subset of ALT alleles match are compatible + + 'all';; + all records are compatible, regardless of whether the ALT alleles + match or not. In the case of records with the same position, only + the first will be considered and appear on output. + + 'snps';; + any SNP records are compatible, regardless of whether the ALT + alleles match or not. For duplicate positions, only the first SNP + record will be considered and appear on output. + + 'indels';; + all indel records are compatible, regardless of whether the REF + and ALT alleles match or not. For duplicate positions, only the + first indel record will be considered and appear on output. + + 'both';; + abbreviation of "*-c* 'indels'{nbsp} *-c* 'snps'" + + 'id';; + only records with identical ID column are compatible. + Supported by *<>* only. + +*-f, --apply-filters* 'LIST':: + Skip sites where FILTER column does not contain any of the strings listed + in 'LIST'. For example, to include only sites which have no filters set, + use *-f* '.,PASS'. + +*--no-version*:: + Do not append version and command line information to the output VCF header. + +*-o, --output* 'FILE':: + When output consists of a single stream, write it to 'FILE' rather than + to standard output, where it is written by default. + +*-O, --output-type* 'b'|'u'|'z'|'v':: + Output compressed BCF ('b'), uncompressed BCF ('u'), compressed VCF ('z'), uncompressed VCF ('v'). + Use the -Ou option when piping between bcftools subcommands to speed up + performance by removing unnecessary compression/decompression and + VCF<-->BCF conversion. + +*-r, --regions* 'chr'|'chr:pos'|'chr:from-to'|'chr:from-'[,...]:: + Comma-separated list of regions, see also *-R, --regions-file*. Note + that *-r* cannot be used in combination with *-R*. + +*-R, --regions-file* 'FILE':: + Regions can be specified either on command line or in a VCF, BED, or + tab-delimited file (the default). The columns of the tab-delimited file + are: CHROM, POS, and, optionally, POS_TO, where positions are 1-based + and inclusive. The columns of the tab-delimited BED file are also + CHROM, POS and POS_TO (trailing columns are ignored), but coordinates + are 0-based, half-open. To indicate that a file be treated as BED rather + than the 1-based tab-delimited file, the file must have the ".bed" or + ".bed.gz" suffix (case-insensitive). Uncompressed files are stored in + memory, while bgzip-compressed and tabix-indexed region files are streamed. + Note that sequence names must match exactly, "chr20" is not the same as + "20". Also note that chromosome ordering in 'FILE' will be respected, + the VCF will be processed in the order in which chromosomes first appear + in 'FILE'. However, within chromosomes, the VCF will always be + processed in ascending genomic coordinate order no matter what order they + appear in 'FILE'. Note that overlapping regions in 'FILE' can result in + duplicated out of order positions in the output. + This option requires indexed VCF/BCF files. Note that *-R* cannot be used + in combination with *-r*. + +*-s, --samples* \[^]'LIST':: + Comma-separated list of samples to include or exclude if prefixed + with "^". + Note that in general tags such as INFO/AC, INFO/AN, etc are not updated + to correspond to the subset samples. *<>* is the + exception where some tags will be updated (unless the *-I, --no-update* + option is used; see *<>* documentation). To use updated + tags for the subset in another command one can pipe from *view* into + that command. For example: +---- + bcftools view -Ou -s sample1,sample2 file.vcf | bcftools query -f %INFO/AC\t%INFO/AN\n +---- + +*-S, --samples-file* [^]'FILE'[[samples_file]]:: + File of sample names to include or exclude if prefixed with "^". + One sample per line. See also the note above for the *-s, --samples* + option. + The command *<>* accepts an optional second + column indicating ploidy (0, 1 or 2) or sex (as defined by + *<>*, for example "F" or "M"), and can parse also PED + files. If the second column is not present, + the sex "F" is assumed. + With *<> -C* 'trio', PED file is expected. File + formats examples: +---- + sample1 1 + sample2 2 + sample3 2 + + or + + sample1 M + sample2 F + sample3 F + + or a .ped file (here is shown a minimum working example, the first column is + ignored and the last indicates sex: 1=male, 2=female) + + ignored daughterA fatherA motherA 2 + ignored sonB fatherB motherB 1 +---- + +*-t, --targets* \[^]'chr'|'chr:pos'|'chr:from-to'|'chr:from-'[,...]:: + Similar as *-r, --regions*, but the next position is accessed by streaming the + whole VCF/BCF rather than using the tbi/csi index. Both *-r* and *-t* options + can be applied simultaneously: *-r* uses the index to jump to a region + and *-t* discards positions which are not in the targets. Unlike *-r*, targets + can be prefixed with "^" to request logical complement. For example, "^X,Y,MT" + indicates that sequences X, Y and MT should be skipped. + Yet another difference between the two is that *-r* checks both start and + end positions of indels, whereas *-t* checks start positions only. Note + that *-t* cannot be used in combination with *-T*. + +*-T, --targets-file* \[^]'FILE':: + Same *-t, --targets*, but reads regions from a file. Note that *-T* + cannot be used in combination with *-t*. + + :: + With the *call -C* 'alleles' command, third column of the targets file must + be comma-separated list of alleles, starting with the reference allele. + Note that the file must be compressed and index. + Such a file can be easily created from a VCF using: +---- + bcftools query -f'%CHROM\t%POS\t%REF,%ALT\n' file.vcf | bgzip -c > als.tsv.gz && tabix -s1 -b2 -e2 als.tsv.gz +---- + +*--threads* 'INT':: + Number of output compression threads to use in addition to main thread. + Only used when '--output-type' is 'b' or 'z'. Default: 0. + + +[[annotate]] +=== bcftools annotate '[OPTIONS]' 'FILE' + +Add or remove annotations. + +*-a, --annotations* 'file':: + Bgzip-compressed and tabix-indexed file with annotations. The file + can be VCF, BED, or a tab-delimited file with mandatory columns CHROM, POS + (or, alternatively, FROM and TO), optional columns REF and ALT, and arbitrary + number of annotation columns. BED files are expected to have + the ".bed" or ".bed.gz" suffix (case-insensitive), otherwise a tab-delimited file is assumed. + Note that in case of tab-delimited file, the coordinates POS, FROM and TO are + one-based and inclusive. When REF and ALT are present, only matching VCF + records will be annotated. + When multiple ALT alleles are present in the annotation file (given as + comma-separated list of alleles), at least one must match one of the + alleles in the corresponding VCF record. Similarly, at least one + alternate allele from a multi-allelic VCF record must be present in the + annotation file. + Note that flag types, such as "INFO/FLAG", can be annotated by including + a field with the value "1" to set the flag, "0" to remove it, or "." to + keep existing flags. + See also *-c, --columns* and *-h, --header-lines*. +---- + # Sample annotation file with columns CHROM, POS, STRING_TAG, NUMERIC_TAG + 1 752566 SomeString 5 + 1 798959 SomeOtherString 6 + # etc. +---- + +*--collapse* 'snps'|'indels'|'both'|'all'|'some'|'none':: + Controls how to match records from the annotation file to the target VCF. + Effective only when *-a* is a VCF or BCF. + See *<>* for more. + +*-c, --columns* 'list':: + Comma-separated list of columns or tags to carry over from the annotation file + (see also *-a, --annotations*). If the annotation file is not a VCF/BCF, + 'list' describes the columns of the annotation file and must include CHROM, + POS (or, alternatively, FROM and TO), and optionally REF and ALT. Unused + columns which should be ignored can be indicated by "-". + + + If the annotation file is a VCF/BCF, only the edited columns/tags must be present and their + order does not matter. The columns ID, QUAL, FILTER, INFO and FORMAT + can be edited, where INFO tags can be written both as "INFO/TAG" or simply "TAG", + and FORMAT tags can be written as "FORMAT/TAG" or "FMT/TAG". + The imported VCF annotations can be renamed as "DST_TAG:=SRC_TAG" or "FMT/DST_TAG:=FMT/SRC_TAG". + + + To carry over all INFO annotations, use "INFO". To add all INFO annotations except + "TAG", use "^INFO/TAG". By default, existing values are replaced. + + + To add annotations without overwriting existing values (that is, to add missing tags or + add values to existing tags with missing values), use "+TAG" instead of "TAG". + To append to existing values (rather than replacing or leaving untouched), use "=TAG" + (instead of "TAG" or "+TAG"). + To replace only existing values without modifying missing annotations, use "-TAG". + + + If the annotation file is not a VCF/BCF, all new annotations must be + defined via *-h, --header-lines*. + +*-e, --exclude* 'EXPRESSION':: + exclude sites for which 'EXPRESSION' is true. For valid expressions see + *<>*. + +*-h, --header-lines* 'file':: + Lines to append to the VCF header, see also *-c, --columns* and *-a, --annotations*. For example: +---- + ##INFO= + ##INFO= +---- + +*-I, --set-id* \[+]'FORMAT':: + assign ID on the fly. The format is the same as in the *<>* + command (see below). By default all existing IDs are replaced. If the + format string is preceded by "+", only missing IDs will be set. For example, + one can use +---- + bcftools annotate --set-id +'%CHROM\_%POS\_%REF\_%FIRST_ALT' file.vcf +---- + +*-i, --include* 'EXPRESSION':: + include only sites for which 'EXPRESSION' is true. For valid expressions see + *<>*. + +*-m, --mark-sites* [+-]'TAG':: + annotate sites which are present ("+") or absent ("-") in the *-a* file with a new INFO/TAG flag + +*--no-version*:: + see *<>* + +*-o, --output* 'FILE':: + see *<>* + +*-O, --output-type* 'b'|'u'|'z'|'v':: + see *<>* + + +*-r, --regions* 'chr'|'chr:pos'|'chr:from-to'|'chr:from-'[,...]:: + see *<>* + +*-R, --regions-file* 'file':: + see *<>* + +*--rename-chrs* 'file':: + rename chromosomes according to the map in 'file', with + "old_name new_name\n" pairs separated by whitespaces, each on a separate + line. + +*-s, --samples* \[^]'LIST':: + subset of samples to annotate, see also *<>* + +*-S, --samples-file* 'FILE':: + subset of samples to annotate. If the samples are named differently in the + target VCF and the *-a, --annotations* VCF, the name mapping can be + given as "src_name dst_name\n", separated by whitespaces, each pair on a + separate line. + +*--threads* 'INT':: + see *<>* + +*-x, --remove* 'list':: + List of annotations to remove. Use "FILTER" to remove all filters or + "FILTER/SomeFilter" to remove a specific filter. Similarly, "INFO" can + be used to remove all INFO tags and "FORMAT" to remove all FORMAT tags + except GT. To remove all INFO tags except "FOO" and "BAR", use + "^INFO/FOO,INFO/BAR" (and similarly for FORMAT and FILTER). + "INFO" can be abbreviated to "INF" and "FORMAT" to "FMT". + +*Examples:* +---- + # Remove three fields + bcftools annotate -x ID,INFO/DP,FORMAT/DP file.vcf.gz + + # Remove all INFO fields and all FORMAT fields except for GT and PL + bcftools annotate -x INFO,^FORMAT/GT,FORMAT/PL file.vcf + + # Add ID, QUAL and INFO/TAG, not replacing TAG if already present + bcftools annotate -a src.bcf -c ID,QUAL,+TAG dst.bcf + + # Carry over all INFO and FORMAT annotations except FORMAT/GT + bcftools annotate -a src.bcf -c INFO,^FORMAT/GT dst.bcf + + # Annotate from a tab-delimited file with six columns (the fifth is ignored), + # first indexing with tabix. The coordinates are 1-based. + tabix -s1 -b2 -e2 annots.tab.gz + bcftools annotate -a annots.tab.gz -h annots.hdr -c CHROM,POS,REF,ALT,-,TAG file.vcf + + # Annotate from a tab-delimited file with regions (1-based coordinates, inclusive) + tabix -s1 -b2 -e3 annots.tab.gz + bcftools annotate -a annots.tab.gz -h annots.hdr -c CHROM,FROM,TO,TAG inut.vcf + + # Annotate from a bed file (0-based coordinates, half-closed, half-open intervals) + bcftools annotate -a annots.bed.gz -h annots.hdr -c CHROM,FROM,TO,TAG input.vcf +---- + + + +[[call]] +=== bcftools call '[OPTIONS]' 'FILE' + +This command replaces the former *bcftools view* caller. Some of the original +functionality has been temporarily lost in the process of transition under +http://github.com/samtools/htslib[htslib], but will be added back on popular +demand. The original calling model can be invoked with the *-c* option. + +==== File format options: + +*--no-version*:: + see *<>* + +*-o, --output* 'FILE':: + see *<>* + +*-O, --output-type* 'b'|'u'|'z'|'v':: + see *<>* + +*--ploidy* 'ASSEMBLY'['?'][[ploidy]]:: + predefined ploidy, use 'list' (or any other unused word) to print a list + of all predefined assemblies. Append a question mark to print the actual + definition. See also *--ploidy-file*. + +*--ploidy-file* 'FILE':: + ploidy definition given as a space/tab-delimited list of + CHROM, FROM, TO, SEX, PLOIDY. The SEX codes are arbitrary and + correspond to the ones used by *<>*. + The default ploidy can be given using the starred records (see + below), unlisted regions have ploidy 2. The default ploidy definition is +---- + X 1 60000 M 1 + X 2699521 154931043 M 1 + Y 1 59373566 M 1 + Y 1 59373566 F 0 + MT 1 16569 M 1 + MT 1 16569 F 1 + * * * M 2 + * * * F 2 +---- + +*-r, --regions* 'chr'|'chr:pos'|'chr:from-to'|'chr:from-'[,...]:: + see *<>* + +*-R, --regions-file* 'file':: + see *<>* + +*-s, --samples* 'LIST':: + see *<>* + +*-S, --samples-file* 'FILE':: + see *<>* + +*-t, --targets* 'LIST':: + see *<>* + +*-T, --targets-file* 'FILE':: + see *<>* + +*--threads* 'INT':: + see *<>* + +==== Input/output options: + +*-A, --keep-alts*:: + output all alternate alleles present in the alignments even if they do not + appear in any of the genotypes + +*-f, --format-fields* 'list':: + comma-separated list of FORMAT fields to output for each sample. Currently + GQ and GP fields are supported. For convenience, the fields can be given + as lower case letters. + +*-F, --prior-freqs* 'AN','AC':: + take advantage of prior knowledge of population allele frequencies. The + workflow looks like this: +---- + # Extract AN,AC values from an existing VCF, such 1000Genomes + bcftools query -f'%CHROM\t%POS\t%REF\t%ALT\t%AN\t%AC\n' 1000Genomes.bcf | bgzip -c > AFs.tab.gz + + # If the tags AN,AC are not already present, use the +fill-AN-AC plugin + bcftools +fill-AN-AC 1000Genomes.bcf | bcftools query -f'%CHROM\t%POS\t%REF\t%ALT\t%AN\t%AC\n' | bgzip -c > AFs.tab.gz + tabix -s1 -b2 -e2 AFs.tab.gz + + # Create a VCF header description, here we name the tags REF_AN,REF_AC + cat AFs.hdr + ##INFO= + ##INFO= + + # Now before calling, stream the raw mpileup output through `bcftools annotate` to add the frequencies + bcftools mpileup [...] -Ou | bcftools annotate -a AFs.tab.gz -h AFs.hdr -c CHROM,POS,REF,ALT,REF_AN,REF_AC -Ou | bcftools call -mv -F REF_AN,REF_AC [...] +---- + +*-g, --gvcf* 'INT':: + output also gVCF blocks of homozygous REF calls. The parameter 'INT' is the + minimum per-sample depth required to include a site in the non-variant + block. + +*-i, --insert-missed* 'INT':: + output also sites missed by mpileup but present in *-T, --targets-file*. + +*-M, --keep-masked-ref*:: + output sites where REF allele is N + +*-V, --skip-variants* 'snps'|'indels':: + skip indel/SNP sites + +*-v, --variants-only*:: + output variant sites only + +==== Consensus/variant calling options: + +*-c, --consensus-caller*:: + the original *samtools*/*bcftools* calling method (conflicts with *-m*) + +*-C, --constrain* 'alleles'|'trio':: + + 'alleles';; + call genotypes given alleles. See also *-T, --targets-file*. + + 'trio';; + call genotypes given the father-mother-child constraint. See also + *-s, --samples* and *-n, --novel-rate*. + +*-m, --multiallelic-caller*:: + alternative modelfor multiallelic and rare-variant calling designed to + overcome known limitations in *-c* calling model (conflicts with *-c*) + +*-n, --novel-rate* 'float'[,...]:: + likelihood of novel mutation for constrained *-C* 'trio' calling. The trio + genotype calling maximizes likelihood of a particular combination of + genotypes for father, mother and the child + P(F=i,M=j,C=k) = P(unconstrained) * Pn + P(constrained) * (1-Pn). + By providing three values, the mutation rate Pn is set explicitly for SNPs, + deletions and insertions, respectively. If two values are given, the first + is interpreted as the mutation rate of SNPs and the second is used to + calculate the mutation rate of indels according to their length as + Pn='float'*exp(-a-b*len), where a=22.8689, b=0.2994 for insertions and + a=21.9313, b=0.2856 for deletions [pubmed:23975140]. If only one value is + given, the same mutation rate Pn is used for SNPs and indels. + +*-p, --pval-threshold* 'float':: + with *-c*, accept variant if P(ref|D) < 'float'. + +*-P, --prior* 'float':: + expected substitution rate, or 0 to disable the prior. Only with *-m*. + +*-t, --targets* 'file'|'chr'|'chr:pos'|'chr:from-to'|'chr:from-'[,...]:: + see *<>* + +*-X, --chromosome-X*:: + haploid output for male samples (requires PED file with *-s*) + +*-Y, --chromosome-Y*:: + haploid output for males and skips females (requires PED file with *-s*) + + +[[cnv]] +=== bcftools cnv '[OPTIONS]' 'FILE' + +Copy number variation caller, requires a VCF annotated with the Illumina's +B-allele frequency (BAF) and Log R Ratio intensity (LRR) values. The HMM +considers the following copy number states: CN 2 (normal), 1 (single-copy +loss), 0 (complete loss), 3 (single-copy gain). + + +==== General Options: + +*-c, --control-sample* 'string':: + optional control sample name. If given, pairwise calling is performed + and the *-P* option can be used + +*-f, --AF-file* 'file':: + read allele frequencies from a tab-delimited file with the columns CHR,POS,REF,ALT,AF + +*-o, --output-dir 'path':: + output directory + +*-p, --plot-threshold 'float':: + call *matplotlib* to produce plots for chromosomes with quality at least 'float', + useful for visual inspection of the calls. With *-p 0*, plots for all chromosomes will be + generated. If not given, a *matplotlib* script will be created but not called. + +*-r, --regions* 'chr'|'chr:pos'|'chr:from-to'|'chr:from-'[,...]:: + see *<>* + +*-R, --regions-file* 'file':: + see *<>* + +*-s, --query-sample* 'string':: + query samply name + +*-t, --targets* 'LIST':: + see *<>* + +*-T, --targets-file* 'FILE':: + see *<>* + +==== HMM Options: + +*-a, --aberrant* 'float'[,'float']:: + fraction of aberrant cells in query and control. The hallmark of + duplications and contaminations is the BAF value of heterozygous markers + which is dependent on the fraction of aberrant cells. Sensitivity to + smaller fractions of cells can be increased by setting *-a* to a lower value. Note + however, that this comes at the cost of increased false discovery rate. + +*-b, --BAF-weight* 'float':: + relative contribution from BAF + +*d, --BAF-dev* 'float'[,'float']:: + expected BAF deviation in query and control, i.e. the noise observed + in the data. + +*-e, --err-prob* 'float':: + uniform error probability + +*-l, --LRR-weight* 'float':: + relative contribution from LRR. With noisy data, this option can have big effect + on the number of calls produced. In truly random noise (such as in simulated data), + the value should be set high (1.0), but in the presence of systematic noise + when LRR are not informative, lower values result in cleaner calls (0.2). + +*-L, --LRR-smooth-win* 'int':: + reduce LRR noise by applying moving average given this window size + +*-O, --optimize* 'float':: + iteratively estimate the fraction of aberrant cells, down to the given fraction. + Lowering this value from the default 1.0 to say, 0.3, can help discover more + events but also increases noise + +*-P, --same-prob* 'float':: + the prior probability of the query and the control sample being the same. + Setting to 0 calls both independently, setting to 1 forces the same copy + number state in both. + +*-x, --xy-prob* 'float':: + the HMM probability of transition to another copy number state. Increasing this + values leads to smaller and more frequent calls. + + + +[[concat]] +=== bcftools concat '[OPTIONS]' 'FILE1' 'FILE2' [...] + +Concatenate or combine VCF/BCF files. All source files must have the same sample +columns appearing in the same order. Can be used, for example, to +concatenate chromosome VCFs into one VCF, or combine a SNP VCF and an indel +VCF into one. The input files must be sorted by chr and position. The files +must be given in the correct order to produce sorted VCF on output unless +the *-a, --allow-overlaps* option is specified. With the --naive option, the files +are concatenated without being recompressed, which is very fast but dangerous +if the BCF headers differ. + + +*-a, --allow-overlaps*:: + First coordinate of the next file can precede last record of the current file. + +*-c, --compact-PS*:: + Do not output PS tag at each site, only at the start of a new phase set block. + +*-d, --rm-dups* 'snps'|'indels'|'both'|'all'|'none':: + Output duplicate records of specified type present in multiple files only once. + Requires *-a, --allow-overlaps*. + +*-D, --remove-duplicates*:: + Alias for *-d none* + +*-f, --file-list* 'FILE':: + Read file names from 'FILE', one file name per line. + +*-l, --ligate*:: + Ligate phased VCFs by matching phase at overlapping haplotypes + +*--no-version*:: + see *<>* + +*-n, --naive*:: + Concatenate VCF or BCF files without recompression. This is very fast but requires + that all files are of the same type (all VCF or all BCF) and have the same headers. + This is because all tags and chromosome names in the BCF body rely on the implicit + order of the contig and tag definitions in the header. Currently no sanity checks + are in place. Dangerous, use with caution. + +*-o, --output* 'FILE':: + see *<>* + +*-O, --output-type* 'b'|'u'|'z'|'v':: + see *<>* + +*-q, --min-PQ* 'INT':: + Break phase set if phasing quality is lower than 'INT' + +*-r, --regions* 'chr'|'chr:pos'|'chr:from-to'|'chr:from-'[,...]:: + see *<>*. Requires *-a, --allow-overlaps*. + +*-R, --regions-file* 'FILE':: + see *<>*. Requires *-a, --allow-overlaps*. + +*--threads* 'INT':: + see *<>* + + +[[consensus]] +=== bcftools consensus '[OPTIONS]' 'FILE' +Create consensus sequence by applying VCF variants to a reference fasta file. +By default, the program will apply all ALT variants to the reference fasta to +obtain the consensus sequence. Using the *--sample* (and, optionally, +*--haplotype*) option will apply genotype (haplotype) calls from FORMAT/GT. +Note that the program does not act as a primitive variant caller and ignores allelic +depth information, such as INFO/AD or FORMAT/AD. For that, consider using the +*setGT* plugin. + +*-f, --fasta-ref* 'FILE':: + reference sequence in fasta format + +*-H, --haplotype* '1'|'2':: + apply variants for the given haplotype. This option requires *-s*, unless + exactly one sample is present in the VCF + +*-i, --iupac-codes*:: + output variants in the form of IUPAC ambiguity codes + +*-m, --mask* 'FILE':: + BED file or TAB file with regions to be replaced with N. See discussion + of *--regions-file* in *<>* for file + format details. + +*-o, --output* 'FILE':: + write output to a file + +*-s, --sample* 'NAME':: + apply variants of the given sample + +*Examples:* +---- + # Apply variants present in sample "NA001", output IUPAC codes for hets + bcftools consensus -i -s NA001 -f in.fa in.vcf.gz > out.fa + + # Create consensus for one region. The fasta header lines are then expected + # in the form ">chr:from-to". + samtools faidx ref.fa 8:11870-11890 | bcftools consensus in.vcf.gz -o out.fa +---- + + +[[convert]] +=== bcftools convert '[OPTIONS]' 'FILE' + +==== VCF input options: + +*-e, --exclude* 'EXPRESSION':: + exclude sites for which 'EXPRESSION' is true. For valid expressions see + *<>*. + +*-i, --include* 'EXPRESSION':: + include only sites for which 'EXPRESSION' is true. For valid expressions see + *<>*. + +*-r, --regions* 'chr'|'chr:pos'|'chr:from-to'|'chr:from-'[,...]:: + see *<>* + +*-R, --regions-file* 'FILE':: + see *<>* + +*-s, --samples* 'LIST':: + see *<>* + +*-S, --samples-file* 'FILE':: + see *<>* + +*-t, --targets* 'LIST':: + see *<>* + +*-T, --targets-file* 'FILE':: + see *<>* + +==== VCF output options: + +*--no-version*:: + see *<>* + +*-o, --output* 'FILE':: + see *<>* + +*-O, --output-type* 'b'|'u'|'z'|'v':: + see *<>* + +*--threads* 'INT':: + see *<>* + +==== GEN/SAMPLE conversion: +*-G, --gensample2vcf* 'prefix' or 'gen-file','sample-file':: + convert IMPUTE2 output to VCF. The second column must be of the form + "CHROM:POS_REF_ALT" to detect possible strand swaps; IMPUTE2 leaves the + first one empty ("--") when sites from reference panel are filled in. See + also *-g* below. + +*-g, --gensample* 'prefix' or 'gen-file','sample-file':: + convert from VCF to gen/sample format used by IMPUTE2 and SHAPEIT. + The columns of .gen file format are ID1,ID2,POS,A,B followed by three + genotype probabilities P(AA), P(AB), P(BB) for each sample. In order to + prevent strand swaps, the program uses IDs of the form "CHROM:POS_REF_ALT". + For example: +---- + .gen + ---- + 1:111485207_G_A 1:111485207_G_A 111485207 G A 0 1 0 0 1 0 + 1:111494194_C_T 1:111494194_C_T 111494194 C T 0 1 0 0 0 1 + + .sample + ------- + ID_1 ID_2 missing + 0 0 0 + sample1 sample1 0 + sample2 sample2 0 +---- + +*--tag* 'STRING':: + tag to take values for .gen file: GT,PL,GL,GP + +*--chrom*:: + output chromosome in the first column instead of CHROM:POS_REF_ALT + +*--sex* 'FILE':: + output sex column in the sample file. The FILE format is +---- + MaleSample M + FemaleSample F +---- + +*--vcf-ids*:: + output VCF IDs in the second column instead of CHROM:POS_REF_ALT + + +==== gVCF conversion: +*--gvcf2vcf*:: + convert gVCF to VCF, expanding REF blocks into sites. Only sites + with FILTER set to "PASS" or "." will be expanded. + +*-f, --fasta-ref* 'file':: + reference sequence in fasta format. Must be indexed with samtools faidx + + +==== HAPS/SAMPLE conversion: +*--hapsample2vcf* 'prefix' or 'haps-file','sample-file':: + convert from haps/sample format to VCF. The columns of .haps file are + similar to .gen file above, but there are only two haplotype columns per + sample. Note that the first column of the haps file is expected to be in + the form "CHR:POS_REF_ALT(_END)?", with the _END being optional for + defining the INFO/END tag when ALT is a symbolic allele, for example: +---- + .haps + ---- + 1:111485207_G_A rsID1 111485207 G A 0 1 0 0 + 1:111494194_C_T rsID2 111494194 C T 0 1 0 0 + 1:111495231_A__111495784 rsID3 111495231 A 0 0 1 0 +---- + +*--hapsample* 'prefix' or 'haps-file','sample-file':: + convert from VCF to haps/sample format used by IMPUTE2 and SHAPEIT. + The columns of .haps file begin with ID,RSID,POS,REF,ALT. In order to + prevent strand swaps, the program uses IDs of the form + "CHROM:POS_REF_ALT". + +*--haploid2diploid*:: + with *-h* option converts haploid genotypes to homozygous diploid + genotypes. For example, the program will print '0 0' instead of the + default '0 -'. This is useful for programs which do not handle haploid + genotypes correctly. + +*--sex* 'FILE':: + output sex column in the sample file. The FILE format is +---- + MaleSample M + FemaleSample F +---- + +*--vcf-ids*:: + output VCF IDs instead of "CHROM:POS_REF_ALT" IDs + +==== HAPS/LEGEND/SAMPLE conversion: +*-H, --haplegendsample2vcf* 'prefix' or 'haps-file','legend-file','sample-file':: + convert from haps/legend/sample format used by IMPUTE2 to VCF, see + also *-h, --hapslegendsample* below. + +*-h, --haplegendsample* 'prefix' or 'haps-file','legend-file','sample-file':: + convert from VCF to haps/legend/sample format used by IMPUTE2 and SHAPEIT. + The columns of .legend file ID,POS,REF,ALT. In order to prevent strand + swaps, the program uses IDs of the form "CHROM:POS_REF_ALT". The .sample + file is quite basic at the moment with columns for population, group and + sex expected to be edited by the user. For example: +---- + .haps + ----- + 0 1 0 0 1 0 + 0 1 0 0 0 1 + + .legend + ------- + id position a0 a1 + 1:111485207_G_A 111485207 G A + 1:111494194_C_T 111494194 C T + + .sample + ------- + sample population group sex + sample1 sample1 sample1 2 + sample2 sample2 sample2 2 +---- + +*--haploid2diploid*:: + with *-h* option converts haploid genotypes to homozygous diploid + genotypes. For example, the program will print '0 0' instead of the + default '0 -'. This is useful for programs which do not handle haploid + genotypes correctly. + +*--sex* 'FILE':: + output sex column in the sample file. The FILE format is +---- + MaleSample M + FemaleSample F +---- + +*--vcf-ids*:: + output VCF IDs instead of "CHROM:POS_REF_ALT" IDs + +==== TSV conversion: +*--tsv2vcf* 'file':: + convert from TSV (tab-separated values) format (such as generated by + 23andMe) to VCF. The input file fields can be tab- or space- delimited + +*-c, --columns* 'list':: + comma-separated list of fields in the input file. In the current + version, the fields CHROM, POS, ID, and AA are expected and + can appear in arbitrary order, columns which should be ignored in the input + file can be indicated by "-". + The AA field lists alleles on the forward reference strand, + for example "CC" or "CT" for diploid genotypes or "C" + for haploid genotypes (sex chromosomes). Insertions and deletions + are not supported yet, missing data can be indicated with "--". + +*-f, --fasta-ref* 'file':: + reference sequence in fasta format. Must be indexed with samtools faidx + +*-s, --samples* 'LIST':: + list of sample names. See *<>* + +*-S, --samples-file* 'FILE':: + file of sample names. See *<>* + +*Example:* +---- +# Convert 23andme results into VCF +bcftools convert -c ID,CHROM,POS,AA -s SampleName -f 23andme-ref.fa --tsv2vcf 23andme.txt -Oz -o out.vcf.gz +---- + + +[[csq]] +=== bcftools csq '[OPTIONS]' 'FILE' + +Haplotype aware consequence predictor which correctly handles combined +variants such as MNPs split over multiple VCF records, SNPs separated by +an intron (but adjacent in the spliced transcript) or nearby frame-shifting +indels which in combination in fact are not frame-shifting. + +The output VCF is annotated with INFO/BCSQ and FORMAT/BCSQ tag (configurable +with the *-c* option). The latter is a bitmask of indexes to INFO/BCSQ, with +interleaved haplotypes. See the usage examples below for using the %TBCSQ +converter in *query* for extracting a more human readable form from this +bitmask. The contruction of the bitmask limits the number of consequences +that can be referenced in the FORMAT/BCSQ tags. By default this is 16, but +if more are required, see the *--ncsq* option. + +The program requires on input a VCF/BCF file, the reference genome in fasta +format (*--fasta-ref*) and genomic features in the GFF3 format downloadable +from the Ensembl website (*--gff-annot*), and outputs an annotated VCF/BCF +file. Currently, only Ensembl GFF3 files are supported. + +By default, the input VCF should be phased. If phase is unknown, or only +partially known, the *--phase* option can be used to indicate how to handle +unphased data. Alternatively, haplotype aware calling can be turned off +with the *--local-csq* option. + +If conflicting (overlapping) variants within one haplotype are detected, +a warning will be emitted and predictions will be based on only the first +variant in the analysis. + +Symbolic alleles are not supported. They will remain unannotated in the +output VCF and are ignored for the prediction analysis. + + +*-c, --custom-tag* 'STRING':: + use this custom tag to store consequences rather than the default BCSQ tag + +*-e, --exclude* 'EXPRESSION':: + exclude sites for which 'EXPRESSION' is true. For valid expressions see + *<>*. + +*-f, --fasta-ref* 'FILE':: + reference sequence in fasta format (required) + +*-g, --gff-annot* 'FILE':: + GFF3 annotation file (required), such as ftp://ftp.ensembl.org/pub/current_gff3/homo_sapiens/ + +*-i, --include* 'EXPRESSION':: + include only sites for which 'EXPRESSION' is true. For valid expressions see + *<>*. + +*-l, --local-csq*:: + switch off haplotype-aware calling, run localized predictions considering + only one VCF record at a time + +*-n, --ncsq* 'INT':: + maximum number of consequences to consider per site. The INFO/BCSQ column includes + all consequences, but only the first 'INT' will be referenced by the FORMAT/BCSQ fields. + The default value is 16 which corresponds to one integer per diploid + sample. Note that increasing the value leads to increased memory and is rarely necessary. + +*-o, --output* 'FILE':: + see *<>* + +*-O, --output-type* 'b'|'t'|'u'|'z'|'v':: + see *<>*. In addition, a custom tab-delimited + plain text output can be printed ('t'). + +*-p, --phase* 'a'|'m'|'r'|'R'|'s':: + how to construct haplotypes and how to deal with unphased data: + + 'a';; + take GTs as is, create haplotypes regardless of phase (0/1 -> 0|1) + + 'm';; + merge all GTs into a single haplotype (0/1 -> 1, 1/2 -> 1) + + 'r';; + require phased GTs, throw an error on unphased heterozygous GTs + + 'R';; + create non-reference haplotypes if possible (0/1 -> 1|1, 1/2 -> 1|2) + + 's';; + skip unphased GTs + +*-q, --quiet*:: + suppress warning messages + +*-r, --regions* 'chr'|'chr:pos'|'chr:from-to'|'chr:from-'[,...]:: + see *<>* + +*-R, --regions-file* 'FILE':: + see *<>* + +*-s, --samples* 'LIST':: + samples to include or "-" to apply all variants and ignore samples + +*-S, --samples-file* 'FILE':: + see *<>* + +*-t, --targets* 'LIST':: + see *<>* + +*-T, --targets-file* 'FILE':: + see *<>* + +*Examples:* +---- + # Basic usage + bcftools csq -f hs37d5.fa -g Homo_sapiens.GRCh37.82.gff3.gz in.vcf -Ob -o out.bcf + + # Extract the translated haplotype consequences. The following TBCSQ variations + # are recognised: + # %TBCSQ .. print consequences in all haplotypes in separate columns + # %TBCSQ{0} .. print the first haplotype only + # %TBCSQ{1} .. print the second haplotype only + # %TBCSQ{*} .. print a list of unique consquences present in either haplotype + bcftools query -f'[%CHROM\t%POS\t%SAMPLE\t%TBCSQ\n]' out.bcf +---- + +*Examples of BCSQ annotation:* +---- + # Two separate VCF records at positions 2:122106101 and 2:122106102 + # change the same codon. This UV-induced C>T dinucleotide mutation + # has been annotated fully at the position 2:122106101 with + # - consequence type + # - gene name + # - ensembl transcript ID + # - coding strand (+ fwd, - rev) + # - amino acid position (in the coding strand orientation) + # - list of corresponding VCF variants + # The annotation at the second position gives the position of the full + # annotation + BCSQ=missense|CLASP1|ENST00000545861|-|1174P>1174L|122106101G>A+122106102G>A + BCSQ=@122106101 + + # A frame-restoring combination of two frameshift insertions C>CG and T>TGG + BCSQ=@46115084 + BCSQ=inframe_insertion|COPZ2|ENST00000006101|-|18AGRGP>18AQAGGP|46115072C>CG+46115084T>TGG + + # Stop gained variant + BCSQ=stop_gained|C2orf83|ENST00000264387|-|141W>141*|228476140C>T + + # The consequence type of a variant downstream from a stop are prefixed with * + BCSQ=*missense|PER3|ENST00000361923|+|1028M>1028T|7890117T>C +---- + + + +[[filter]] +=== bcftools filter '[OPTIONS]' 'FILE' + +Apply fixed-threshold filters. + +*-e, --exclude* 'EXPRESSION':: + exclude sites for which 'EXPRESSION' is true. For valid expressions see + *<>*. + +*-g, --SnpGap* 'INT':: + filter SNPs within 'INT' base pairs of an indel. The following example + demonstrates the logic of *--SnpGap* '3' applied on a deletion and + an insertion: +---- +The SNPs at positions 1 and 7 are filtered, positions 0 and 8 are not: + 0123456789 + ref .G.GT..G.. + del .A.G-..A.. +Here the positions 1 and 6 are filtered, 0 and 7 are not: + 0123-456789 + ref .G.G-..G.. + ins .A.GT..A.. +---- + +*-G, --IndelGap* 'INT':: + filter clusters of indels separated by 'INT' or fewer base pairs allowing + only one to pass. The following example demonstrates the logic of + *--IndelGap* '2' applied on a deletion and an insertion: +---- +The second indel is filtered: + 012345678901 + ref .GT.GT..GT.. + del .G-.G-..G-.. +And similarly here, the second is filtered: + 01 23 456 78 + ref .A-.A-..A-.. + ins .AT.AT..AT.. +---- + +*-i, --include* 'EXPRESSION':: + include only sites for which 'EXPRESSION' is true. For valid expressions see + *<>*. + +*-m, --mode* ['+x']:: + define behaviour at sites with existing FILTER annotations. The default + mode replaces existing filters of failed sites with a new FILTER string + while leaving sites which pass untouched when non-empty and setting to + "PASS" when the FILTER string is absent. The "\+" mode appends new FILTER + strings of failed sites instead of replacing them. The "x" mode resets + filters of sites which pass to "PASS". Modes "+" and "x" can both be set. + +*--no-version*:: + see *<>* + +*-o, --output* 'FILE':: + see *<>* + +*-O, --output-type* 'b'|'u'|'z'|'v':: + see *<>* + +*-r, --regions* 'chr'|'chr:pos'|'chr:from-to'|'chr:from-'[,...]:: + see *<>* + +*-R, --regions-file* 'file':: + see *<>* + +*-s, --soft-filter* 'STRING'|'+':: + annotate FILTER column with 'STRING' or, with '+', a unique filter name generated + by the program ("Filter%d"). + +*-S, --set-GTs* '.'|'0':: + set genotypes of failed samples to missing value ('.') or reference allele ('0') + +*-t, --targets* 'chr'|'chr:pos'|'chr:from-to'|'chr:from-'[,...]:: + see *<>* + +*-T, --targets-file* 'file':: + see *<>* + +*--threads* 'INT':: + see *<>* + + + +[[gtcheck]] +=== bcftools gtcheck ['OPTIONS'] [*-g* 'genotypes.vcf.gz'] 'query.vcf.gz' +Checks sample identity or, without *-g*, multi-sample cross-check is performed. + +*-a, --all-sites*:: + output for all sites + +*-c, --cluster* 'FLOAT','FLOAT':: + min inter- and max intra-sample error [0.23,-0.3] + + The first "min" argument controls the typical error rate in multiplexed + runs ("lanelets") from the same sample. Lanelets with error rate less + than this will always be considered as coming from the same sample. + The second "max" argument is the reverse: lanelets with error rate + greater than the absolute value of this parameter will always be + considered as different samples. When the value is negative, the cutoff + may be heuristically lowered by the clustering engine. If positive, the + value is interpreted as a fixed cutoff. + +*-g, --genotypes* 'genotypes.vcf.gz':: + reference genotypes to compare against + +*-G, --GTs-only* 'INT':: + use genotypes (GT) instead of genotype likelihoods (PL). When set to 1, + reported discordance is the number of non-matching GTs, otherwise the + number 'INT' is interpreted as phred-scaled likelihood of unobserved + genotypes. + +*-H, --homs-only*:: + consider only genotypes which are homozygous in both 'genotypes' and + 'query' VCF. This may be useful with low coverage data. + +*-p, --plot* 'PREFIX':: + produce plots + +*-r, --regions* 'chr'|'chr:pos'|'chr:from-to'|'chr:from-'[,...]:: + see *<>* + +*-R, --regions-file* 'file':: + see *<>* + +*-s, --query-sample* 'STRING':: + query sample in 'query.vcf.gz'. By default, the first sample is checked. + +*-S, --target-sample* 'STRING':: + target sample in the *-g* file, used only for plotting, not for analysis + +*-t, --targets* 'file':: + see *<>* + +*-T, --targets-file* 'file':: + see *<>* + +==== Output files format: + CN, Discordance;; + Pairwise discordance for all sample pairs is calculated as +---- + \sum_s { min_G { PL_a(G) + PL_b(G) } }, +---- + ;; + where the sum runs over all sites 's' and 'G' is the the most likely + genotype shared by both samples 'a' and 'b'. When PL field is not + present, a constant value '99' is used for the unseen genotypes. With + *-G*, the value '1' can be used instead; the discordance value then + gives exactly the number of differing genotypes. + + SM, Average Discordance;; + Average discordance between sample 'a' and all other samples. + + SM, Average Depth;; + Average depth at evaluated sites, or 1 if FORMAT/DP field is not + present. + + SM, Average Number of sites;; + The average number of sites used to calculate the discordance. In + other words, the average number of non-missing PLs/genotypes seen + both samples. + +// MD, Maximum Deviation;; +// The maximum absolute deviation from average score of the sample +// most dissimilar to the rest. + + +[[index]] +=== bcftools index ['OPTIONS'] 'in.bcf'|'in.vcf.gz' +Creates index for bgzip compressed VCF/BCF files for random access. CSI +(coordinate-sorted index) is created by default. The CSI format +supports indexing of chromosomes up to length 2^31. TBI (tabix index) +index files, which support chromosome lengths up to 2^29, can be +created by using the '-t/--tbi' option or using the 'tabix' program +packaged with htslib. When loading an index file, bcftools will try +the CSI first and then the TBI. + +==== Indexing options: +*-c, --csi*:: + generate CSI-format index for VCF/BCF files [default] + +*-f, --force*:: + overwrite index if it already exists + +*-m, --min-shift 'INT'*:: + set minimal interval size for CSI indices to 2^INT; default: 14 + +*-o, --output-file 'FILE'*:: + output file name. If not set, then the index will be created + using the input file name plus a '.csi' or '.tbi' extension + +*-t, --tbi*:: + generate TBI-format index for VCF files + +*--threads* 'INT':: + see *<>* + +==== Stats options: +*-n, --nrecords*:: + print the number of records based on the CSI or TBI index files + +*-s, --stats*:: + Print per contig stats based on the CSI or TBI index files. + Output format is three tab-delimited columns listing the contig + name, contig length ('.' if unknown) and number of records for + the contig. Contigs with zero records are not printed. + +[[isec]] +=== bcftools isec ['OPTIONS'] 'A.vcf.gz' 'B.vcf.gz' [...] +Creates intersections, unions and complements of VCF files. Depending +on the options, the program can output records from one (or more) files +which have (or do not have) corresponding records with the same position +in the other files. + +*-c, --collapse* 'snps'|'indels'|'both'|'all'|'some'|'none':: + see *<>* + +*-C, --complement*:: + output positions present only in the first file but missing in the others + +*-e, --exclude* '-'|'EXPRESSION':: + exclude sites for which 'EXPRESSION' is true. If *-e* (or *-i*) + appears only once, the same filtering expression will be applied to all + input files. Otherwise, *-e* or *-i* must be given for each input file. + To indicate that no filtering should be performed on a file, use "-" in + place of 'EXPRESSION', as shown in the example below. + For valid expressions see *<>*. + +*-f, --apply-filters* 'LIST':: + see *<>* + +*-i, --include* 'EXPRESSION':: + include only sites for which 'EXPRESSION' is true. See discussion + of *-e, --exclude* above. + +*-n, --nfiles* \[+-=]'INT'|~'BITMAP':: + output positions present in this many (=), this many or more (+), this + many or fewer (-), or the exact same (~) files + +*-o, --output* 'FILE':: + see *<>*. When several files are being + output, their names are controlled via *-p* instead. + +*-O, --output-type* 'b'|'u'|'z'|'v':: + see *<>* + +*-p, --prefix* 'DIR':: + if given, subset each of the input files accordingly. See also *-w*. + +*-r, --regions* 'chr'|'chr:pos'|'chr:from-to'|'chr:from-'[,...]:: + see *<>* + +*-R, --regions-file* 'file':: + see *<>* + +*-t, --targets* 'chr'|'chr:pos'|'chr:from-to'|'chr:from-'[,...]:: + see *<>* + +*-T, --targets-file* 'file':: + see *<>* + +*-w, --write* 'LIST':: + list of input files to output given as 1-based indices. With *-p* and no + *-w*, all files are written. + +==== Examples: + +Create intersection and complements of two sets saving the output in dir/* +---- + bcftools isec -p dir A.vcf.gz B.vcf.gz +---- + +Filter sites in A and B (but not in C) and create intersection +---- + bcftools isec -e'MAF<0.01' -i'dbSNP=1' -e- A.vcf.gz B.vcf.gz C.vcf.gz -p dir +---- + +Extract and write records from A shared by both A and B using exact allele match +---- + bcftools isec -p dir -n=2 -w1 A.vcf.gz B.vcf.gz +---- + +Extract records private to A or B comparing by position only +---- + bcftools isec -p dir -n-1 -c all A.vcf.gz B.vcf.gz +---- + +Print a list of records which are present in A and B but not in C and D +---- + bcftools isec -n~1100 -c all A.vcf.gz B.vcf.gz C.vcf.gz D.vcf.gz +---- + + +[[merge]] +=== bcftools merge ['OPTIONS'] 'A.vcf.gz' 'B.vcf.gz' [...] +Merge multiple VCF/BCF files from non-overlapping sample sets to create one +multi-sample file. For example, when merging file 'A.vcf.gz' containing +samples 'S1', 'S2' and 'S3' and file 'B.vcf.gz' containing samples 'S3' and +'S4', the output file will contain four samples named 'S1', 'S2', 'S3', '2:S3' +and 'S4'. + +Note that it is responsibility of the user to ensure that the sample names are +unique across all files. If they are not, the program will exit with an error +unless the option *--force-samples* is given. The sample names can be +also given explicitly using the *--print-header* and *--use-header* options. + +Note that only records from different files can be merged, never from the same file. +For "vertical" merge take a look at *<>* instead. + + +*--force-samples*:: + if the merged files contain duplicate samples names, proceed anyway. + Duplicate sample names will be resolved by prepending index of the file + as it appeared on the command line to the conflicting sample name (see + '2:S3' in the above example). + +*--print-header*:: + print only merged header and exit + +*--use-header* 'FILE':: + use the VCF header in the provided text 'FILE' + +*-0 --missing-to-ref*:: + assume genotypes at missing sites are 0/0 + +*-f, --apply-filters* 'LIST':: + see *<>* + +*-F, --filter-logic* 'x'|'+':: + Set the output record to PASS if any of the inputs is PASS ('x'), + or apply all filters ('+'), which is the default. + +*-g, --gvcf* '-'|'FILE':: + merge gVCF blocks, INFO/END tag is expected. If the reference fasta + file 'FILE' is not given and the dash ('-') is given, unknown reference + bases generated at gVCF block splits will be substituted with N's. + The *--gvcf* option uses the following default INFO rules: + *-i QS:sum,MinDP:min,I16:sum,IDV:max,IMF:max*. + +*-i, --info-rules* '-'|'TAG:METHOD'[,...]:: + Rules for merging INFO fields (scalars or vectors) or '-' to disable the + default rules. 'METHOD' is one of 'sum', 'avg', 'min', 'max', 'join'. + Default is 'DP:sum,DP4:sum' if these fields exist in the input files. + Fields with no specified rule will take the value from the first input file. + The merged QUAL value is currently set to the maximum. This behaviour is + not user controllable at the moment. + +*-l, --file-list* 'FILE':: + Read file names from 'FILE', one file name per line. + +*-m, --merge* 'snps'|'indels'|'both'|'all'|'none'|'id':: + The option controls what types of multiallelic records can be created: +---- +-m none .. no new multiallelics, output multiple records instead +-m snps .. allow multiallelic SNP records +-m indels .. allow multiallelic indel records +-m both .. both SNP and indel records can be multiallelic +-m all .. SNP records can be merged with indel records +-m id .. merge by ID +---- + +*--no-version*:: + see *<>* + +*-o, --output* 'FILE':: + see *<>* + +*-O, --output-type* 'b'|'u'|'z'|'v':: + see *<>* + +*-r, --regions* 'chr'|'chr:pos'|'chr:from-to'|'chr:from-'[,...]:: + see *<>* + +*-R, --regions-file* 'file':: + see *<>* + +*--threads* 'INT':: + see *<>* + + +[[mpileup]] +=== bcftools mpileup ['OPTIONS'] *-f* 'ref.fa' 'in.bam' ['in2.bam' [...]] +Generate VCF or BCF containing genotype likelihoods for one or multiple +alignment (BAM or CRAM) files. This is based on the original +*samtools mpileup* command (with the *-v* or *-g* options) producing +genotype likelihoods in VCF or BCF format, but not the textual pileup +output. The *mpileup* command was transferred to bcftools in order to +avoid errors resulting from use of incompatible versions of samtools +and bcftools when using in the mpileup+bcftools call pipeline. + +Individuals are identified from the SM tags in the @RG header lines. Multiple +individuals can be pooled in one alignment file, also one individual can be +separated into multiple files. If sample identifiers are absent, each input +file is regarded as one sample. + +Note that there are two orthogonal ways to specify locations in the +input file; via *-r* 'region' and *-t* 'positions'. The +former uses (and requires) an index to do random access while the +latter streams through the file contents filtering out the specified +regions, requiring no index. The two may be used in conjunction. For +example a BED file containing locations of genes in chromosome 20 +could be specified using *-r 20 -t chr20.bed*, meaning that the +index is used to find chromosome 20 and then it is filtered for the +regions listed in the BED file. Also note that the *-r* option can be much +slower than *-t* with many regions and can require more memory when +multiple regions and many alignment files are processed. + + +==== Input options + +*-6, --illumina1.3+*:: + Assume the quality is in the Illumina 1.3+ encoding. + +*-A, --count-orphans*:: + Do not skip anomalous read pairs in variant calling. + +*-b, --bam-list* 'FILE':: + List of input alignment files, one file per line [null] + +*-B, --no-BAQ*:: + Disable probabilistic realignment for the computation of base alignment + quality (BAQ). BAQ is the Phred-scaled probability of a read base being + misaligned. Applying this option greatly helps to reduce false SNPs caused + by misalignments. + +*-C, --adjust-MQ* 'INT':: + Coefficient for downgrading mapping quality for reads containing + excessive mismatches. Given a read with a phred-scaled probability q of + being generated from the mapped posi- tion, the new mapping quality is + about sqrt((INT-q)/INT)*INT. A zero value disables this functionality; if + enabled, the recommended value for BWA is 50. [0] + +*-d, --max-depth* 'INT':: + At a position, read maximally 'INT' reads per input file. Note that bcftools + has a minimum value of '8000/n' where 'n' is the number of input files given + to mpileup. This means the default is highly likely to be increased. Once + above the cross-sample minimum of 8000 the -d parameter will have an effect. + [250] + +*-E, --redo-BAQ*:: + Recalculate BAQ on the fly, ignore existing BQ tags + +*-f, --fasta-ref* 'FILE':: + The *faidx*-indexed reference file in the FASTA format. The file can be + optionally compressed by *bgzip*. Reference is required by default + unless the *--no-reference* option is set [null] + +*--no-reference*:: + Do not require the *--fasta-ref* option. + +*-G, --read-groups* [^]'FILE':: + list of read groups to include or exclude if prefixed with "^". + One read group per line. This file can also be used to assign new sample + names to read groups by giving the new sample name as a second + white-space-separated field, like this: "read_group_id new_sample_name". + If the read group name is not unique, also the bam file name can + be included: "read_group_id file_name sample_name". If all + reads from the alignment file should be treated as a single sample, the + asterisk symbol can be used: "* file_name sample_name". Alignments without + a read group ID can be matched with "?". +---- + RG_ID_1 + RG_ID_2 SAMPLE_A + RG_ID_3 SAMPLE_A + RG_ID_4 SAMPLE_B + RG_ID_5 FILE_1.bam SAMPLE_A + RG_ID_6 FILE_2.bam SAMPLE_A + * FILE_3.bam SAMPLE_C + ? FILE_3.bam SAMPLE_D +---- + +*-q, -min-MQ* 'INT':: + Minimum mapping quality for an alignment to be used [0] + +*-Q, --min-BQ* 'INT':: + Minimum base quality for a base to be considered [13] + +*-r, --regions* 'CHR'|'CHR:POS'|'CHR:FROM-TO'|'CHR:FROM-'[,...]:: + Only generate mpileup output in given regions. Requires the alignment files + to be indexed. If used in conjunction with -l then considers the intersection; + see *<>* + +*-R, --regions-file* 'FILE':: + As for *-r, --regions*, but regions read from FILE; + see *<>* + +*--ignore-RG*:: + Ignore RG tags. Treat all reads in one alignment file as one sample. + +*--rf, --incl-flags* 'STR'|'INT':: + Required flags: skip reads with mask bits unset [null] + +*--ff, --excl-flags* 'STR'|'INT':: + Filter flags: skip reads with mask bits set [UNMAP,SECONDARY,QCFAIL,DUP] + +*-s, --samples* [^]'LIST':: + list of sample names. See *<>* + +*-S, --samples-file* [^]'FILE':: + file of sample names to include or exclude if prefixed with "^". + One sample per line. This file can also be used to rename samples by giving + the new sample name as a second white-space-separated column, like this: + "old_name new_name". If a sample name contains spaces, the spaces can be + escaped using the backslash character, for example "Not\ a\ good\ sample\ + name". + +*-t, --targets* 'LIST':: + see *<>* + +*-T, --targets-file* 'FILE':: + see *<>* + +*-x, --ignore-overlaps*:: + Disable read-pair overlap detection. + + +==== Output options + +*-a, --annotate* 'LIST':: + Comma-separated list of FORMAT and INFO tags to output. (case-insensitive, + the "FORMAT/" prefix is optional, and use "?" to list available annotations + on the command line) [null]: + + *FORMAT/AD* .. Allelic depth (Number=R,Type=Integer) + *FORMAT/ADF* .. Allelic depths on the forward strand (Number=R,Type=Integer) + *FORMAT/ADR* .. Allelic depths on the reverse strand (Number=R,Type=Integer) + *FORMAT/DP* .. Number of high-quality bases (Number=1,Type=Integer) + *FORMAT/SP* .. Phred-scaled strand bias P-value (Number=1,Type=Integer) + + *INFO/AD* .. Total allelic depth (Number=R,Type=Integer) + *INFO/ADF* .. Total allelic depths on the forward strand (Number=R,Type=Integer) + *INFO/ADR* .. Total allelic depths on the reverse strand (Number=R,Type=Integer) + + *FORMAT/DV* .. Deprecated in favor of FORMAT/AD; + Number of high-quality non-reference bases, (Number=1,Type=Integer) + *FORMAT/DP4* .. Deprecated in favor of FORMAT/ADF and FORMAT/ADR; + Number of high-quality ref-forward, ref-reverse, + alt-forward and alt-reverse bases (Number=4,Type=Integer) + *FORMAT/DPR* .. Deprecated in favor of FORMAT/AD; + Number of high-quality bases for each observed allele (Number=R,Type=Integer) + *INFO/DPR* .. Deprecated in favor of INFO/AD; + Number of high-quality bases for each observed allele (Number=R,Type=Integer) + +*-g, --gvcf* 'INT'[,...]:: + output gVCF blocks of homozygous REF calls, with depth (DP) ranges + specified by the list of integers. For example, passing '5,15' will + group sites into two types of gVCF blocks, the first with minimum + per-sample DP from the interval [5,15) and the latter with minimum + depth 15 or more. In this example, sites with minimum per-sample + depth less than 5 will be printed as separate records, outside of + gVCF blocks. + +*--no-version*:: + see *<>* + +*-o, --output* 'FILE':: + Write output to 'FILE', rather than the default of standard output. + (The same short option is used for both *--open-prob* and *--output*. If *-o*'s + argument contains any non-digit characters other than a leading + or - + sign, it is interpreted as *--output*. Usually the filename extension + will take care of this, but to write to an entirely numeric filename use *-o + ./123* or *--output 123*.) + +*-O, --output-type* 'b'|'u'|'z'|'v':: + see *<>* + +*--threads* 'INT':: + see *<>* + +==== Options for SNP/INDEL genotype likelihood computation + +*-e, --ext-prob* 'INT':: + Phred-scaled gap extension sequencing error probability. Reducing 'INT' + leads to longer indels [20] + +*-F, --gap-frac* 'FLOAT':: + Minimum fraction of gapped reads [0.002] + +*-h, --tandem-qual* 'INT':: + Coefficient for modeling homopolymer errors. Given an 'l'-long homopolymer + run, the sequencing error of an indel of size s is modeled as 'INT'*s/l [100] + +*-I, --skip-indels*:: + Do not perform INDEL calling + +*-L, --max-idepth* 'INT':: + Skip INDEL calling if the average per-sample depth is above 'INT' [250] + +*-m, --min-ireads* 'INT':: + Minimum number gapped reads for indel candidates 'INT' [1] + +*-o, --open-prob* 'INT':: + Phred-scaled gap open sequencing error probability. Reducing 'INT' leads + to more indel calls. (The same short option is used for both *--open-prob* + and *--output*. When -o's argument contains only an optional + or - sign + followed by the digits 0 to 9, it is interpreted as *--open-prob*.) [40] + +*-p, --per-sample-mF*:: + Apply *-m* and *-F* thresholds per sample to increase sensitivity of calling. + By default both options are applied to reads pooled from all samples. + +*-P, --platforms* 'STR':: + Comma-delimited list of platforms (determined by *@RG-PL*) from which + indel candidates are obtained. It is recommended to collect indel + candidates from sequencing technologies that have low indel error rate + such as ILLUMINA [all] + +==== Examples: + +Call SNPs and short INDELs, then mark low quality sites and sites with the read +depth exceeding a limit. (The read depth should be adjusted to about twice the +average read depth as higher read depths usually indicate problematic regions +which are often enriched for artefacts.) One may consider to add *-C50* to +mpileup if mapping quality is overestimated for reads containing excessive +mismatches. Applying this option usually helps for BWA-backtrack alignments, +but may not other aligners. +---- + bcftools mpileup -Ou -f ref.fa aln.bam | \ + bcftools call -Ou -mv | \ + bcftools filter -s LowQual -e '%QUAL<20 || DP>100' > var.flt.vcf +---- + + +[[norm]] +=== bcftools norm ['OPTIONS'] 'file.vcf.gz' +Left-align and normalize indels, check if REF alleles match the reference, +split multiallelic sites into multiple rows; recover multiallelics from +multiple rows. Left-alignment and normalization will only be applied if +the *<>* option is supplied. + +*-c, --check-ref* 'e'|'w'|'x'|'s':: + what to do when incorrect or missing REF allele is encountered: + exit ('e'), warn ('w'), exclude ('x'), or set/fix ('s') bad sites. + The 'w' option can be combined with 'x' and 's'. Note that 's' + can swap alleles and will update genotypes (GT) and AC counts, + but will not attempt to fix PL or other fields. + +*-d, --rm-dup* 'snps'|'indels'|'both'|'all'|'none':: + If a record is present multiple times, output only the first instance, + see *--collapse* in *<>*. + Requires *-a, --allow-overlaps*. + +*-D, --remove-duplicates*:: + If a record is present in multiple files, output only the first instance. + Alias for *-d none*. Requires *-a, --allow-overlaps*. + +*-f, --fasta-ref* 'FILE'[[fasta_ref]]:: + reference sequence. Supplying this option will turn on left-alignment + and normalization, however, see also the *<>* + option below. + +*-m, --multiallelics* *-*|*+*['snps'|'indels'|'both'|'any']:: + split multiallelic sites into biallelic records (*-*) or join + biallelic sites into multiallelic records (*+*). An optional type string + can follow which controls variant types which should be split or merged + together: If only SNP records should be split or merged, specify 'snps'; if + both SNPs and indels should be merged separately into two records, specify + 'both'; if SNPs and indels should be merged into a single record, specify + 'any'. + +*--no-version*:: + see *<>* + +*-N, --do-not-normalize*[[do_not_normalize]]:: + the '-c s' option can be used to fix or set the REF allele from the + reference '-f'. The '-N' option will not turn on indel normalisation + as the '-f' option normally implies + +*-o, --output* 'FILE':: + see *<>* + +*-O, --output-type* 'b'|'u'|'z'|'v':: + see *<>* + +*-r, --regions* 'chr'|'chr:pos'|'chr:from-to'|'chr:from-'[,...]:: + see *<>* + +*-R, --regions-file* 'file':: + see *<>* + +*-s, --strict-filter*:: + when merging ('-m+'), merged site is PASS only if all sites being merged PASS + +*-t, --targets* 'LIST':: + see *<>* + +*-T, --targets-file* 'FILE':: + see *<>* + +*--threads* 'INT':: + see *<>* + +*-w, --site-win* 'INT':: + maximum distance between two records to consider when locally + sorting variants which changed position during the realignment + + +[[plugin]] + +=== bcftools [plugin 'NAME'|+'NAME'] '[OPTIONS]' 'FILE' -- '[PLUGIN OPTIONS]' + +A common framework for various utilities. The plugins can be used +the same way as normal commands only their name is prefixed with "+". +Most plugins accept two types of parameters: general options shared by all +plugins followed by a separator, and a list of plugin-specific options. There +are some exceptions to this rule, some plugins do not accept the common +options and implement their own parameters. Therefore please pay attention to +the usage examples that each plugin comes with. + + + +==== VCF input options: + +*-e, --exclude* 'EXPRESSION':: + exclude sites for which 'EXPRESSION' is true. For valid expressions see + *<>*. + +*-i, --include* 'EXPRESSION':: + include only sites for which 'EXPRESSION' is true. For valid expressions see + *<>*. + +*-r, --regions* 'chr'|'chr:pos'|'chr:from-to'|'chr:from-'[,...]:: + see *<>* + +*-R, --regions-file* 'file':: + see *<>* + +*-t, --targets* 'chr'|'chr:pos'|'chr:from-to'|'chr:from-'[,...]:: + see *<>* + +*-T, --targets-file* 'file':: + see *<>* + +==== VCF output options: + +*--no-version*:: + see *<>* + +*-o, --output* 'FILE':: + see *<>* + +*-O, --output-type* 'b'|'u'|'z'|'v':: + see *<>* + +*--threads* 'INT':: + see *<>* + +==== Plugin options: + +*-h, --help*:: + list plugin's options + +*-l, --list-plugins*:: + List all available plugins. ++ +By default, appropriate system directories are searched for installed plugins. + You can override this by setting the BCFTOOLS_PLUGINS environment variable + to a colon-separated list of directories to search. + If BCFTOOLS_PLUGINS begins with a colon, ends with a colon, or contains + adjacent colons, the system directories are also searched at that position + in the list of directories. + +*-v, --verbose*:: + print debugging information to debug plugin failure + +*-V, --version*:: + print version string and exit + +==== List of plugins coming with the distribution: + +*GTisec*:: + count genotype intersections across all possible sample subsets in a vcf file + +*GTsubset*:: + output only sites where the requested samples all exclusively share a genotype + +*ad-bias*:: + find positions with wildly varying ALT allele frequency (Fisher test on FMT/AD) + +*af-dist*:: + collect AF deviation stats and GT probability distribution given AF and assuming HWE + +*color-chrs*:: + color shared chromosomal segments, requires trio VCF with phased GTs + +*counts*:: + a minimal plugin which counts number of SNPs, Indels, and total number of sites. + +*dosage*:: + print genotype dosage. By default the plugin searches for PL, GL and GT, in + that order. + +*fill-AN-AC*:: + fill INFO fields AN and AC. + +*fill-from-fasta*:: + fill INFO or REF field based on values in a fasta file + +*fill-tags*:: + set INFO tags AF, AN, AC, NS, AC_Hom, AC_Het, AC_Hemi + +*fix-ploidy*:: + sets correct ploidy + +*fixref*:: + determine and fix strand orientation + +*frameshifts*:: + annotate frameshift indels + +*guess-ploidy*:: + determine sample sex by checking genotype likelihoods (GL,PL) or genotypes (GT) + in the non-PAR region of chrX. + +*impute-info*:: + add imputation information metrics to the INFO field based on selected FORMAT tags + +*mendelian*:: + count Mendelian consistent / inconsistent genotypes. + +*missing2ref*:: + sets missing genotypes ("./.") to ref allele ("0/0" or "0|0") + +*setGT*:: + general tool to set genotypes according to rules requested by the user + +*tag2tag*:: + convert between similar tags, such as GL and GP + +*trio-switch-rate*:: + calculate phase switch rate in trio samples, children samples must have phased GTs. + + +==== Examples: + +---- +# List options common to all plugins +bcftools plugin + +# List available plugins +bcftools plugin -l + +# Run a plugin +bcftools plugin counts in.vcf + +# Run a plugin using the abbreviated "+" notation +bcftools +counts in.vcf + +# The input VCF can be streamed just like in other commands +cat in.vcf | bcftools +counts + +# Print usage information of plugin "dosage" +bcftools +dosage -h + +# Replace missing genotypes with 0/0 +bcftools +missing2ref in.vcf + +# Replace missing genotypes with 0|0 +bcftools +missing2ref in.vcf -- -p +---- + +==== Plugins troubleshooting: + +Things to check if your plugin does not show up in the *bcftools plugin -l* output: + +- Run with the *-v* option for verbose output: *bcftools plugin -lv* +- Does the environment variable BCFTOOLS_PLUGINS include the correct path? + + +==== Plugins API: + +---- +// Short description used by 'bcftools plugin -l' +const char *about(void); + +// Longer description used by 'bcftools +name -h' +const char *usage(void); + +// Called once at startup, allows initialization of local variables. +// Return 1 to suppress normal VCF/BCF header output, -1 on critical +// errors, 0 otherwise. +int init(int argc, char **argv, bcf_hdr_t *in_hdr, bcf_hdr_t *out_hdr); + +// Called for each VCF record, return NULL to suppress the output +bcf1_t *process(bcf1_t *rec); + +// Called after all lines have been processed to clean up +void destroy(void); +---- + + + +[[polysomy]] +=== bcftools polysomy ['OPTIONS'] 'file.vcf.gz' +Detect number of chromosomal copies in VCFs annotates with the Illumina's +B-allele frequency (BAF) values. Note that this command is not compiled +in by default, see the section *Optional Compilation with GSL* in the INSTALL +file for help. + +==== General options: + +*-o, --output-dir* 'path':: + output directory + +*-r, --regions* 'chr'|'chr:pos'|'chr:from-to'|'chr:from-'[,...]:: + see *<>* + +*-R, --regions-file* 'file':: + see *<>* + +*-s, --sample* 'string':: + sample name + +*-t, --targets* 'LIST':: + see *<>* + +*-T, --targets-file* 'FILE':: + see *<>* + +*-v, --verbose*:: + verbose debugging output which gives hints about the thresholds and decisions made + by the program. Note that the exact output can change between versions. + +==== Algorithm options: + +*-b, --peak-size* 'float':: + the minimum peak size considered as a good match can be from the interval [0,1] + where larger is stricter + +*-c, --cn-penalty* 'float':: + a penalty for increasing copy number state. How this works: multiple peaks + are always a better fit than a single peak, therefore the program prefers + a single peak (normal copy number) unless the absolute deviation of the + multiple peaks fit is significantly smaller. Here the meaning of + "significant" is given by the 'float' from the interval [0,1] where + larger is stricter. + +*-f, --fit-th* 'float':: + threshold for goodness of fit (normalized absolute deviation), smaller is stricter + +*-i, --include-aa*:: + include also the AA peak in CN2 and CN3 evaluation. This usually requires increasing *-f*. + +*-m, --min-fraction* 'float':: + minimum distinguishable fraction of aberrant cells. The experience shows that trustworthy + are estimates of 20% and more. + +*-p, --peak-symmetry* 'float':: + a heuristics to filter failed fits where the expected peak symmetry is violated. + The 'float' is from the interval [0,1] and larger is stricter + + +[[query]] +=== bcftools query ['OPTIONS'] 'file.vcf.gz' ['file.vcf.gz' [...]] +Extracts fields from VCF or BCF files and outputs them in user-defined format. + +*-c, --collapse* 'snps'|'indels'|'both'|'all'|'some'|'none':: + see *<>* + +*-e, --exclude* 'EXPRESSION':: + exclude sites for which 'EXPRESSION' is true. For valid expressions see + *<>*. + +*-f, --format* 'FORMAT':: + learn by example, see below + +*-H, --print-header*:: + print header + +*-i, --include* 'EXPRESSION':: + include only sites for which 'EXPRESSION' is true. For valid expressions see + *<>*. + +*-l, --list-samples*:: + list sample names and exit + +*-o, --output* 'FILE':: + see *<>* + +*-r, --regions* 'chr'|'chr:pos'|'chr:from-to'|'chr:from-'[,...]:: + see *<>* + +*-R, --regions-file* 'file':: + see *<>* + +*-s, --samples* 'LIST':: + see *<>* + +*-S, --samples-file* 'FILE':: + see *<>* + +*-t, --targets* 'chr'|'chr:pos'|'chr:from-to'|'chr:from-'[,...]:: + see *<>* + +*-T, --targets-file* 'file':: + see *<>* + +*-u, --allow-undef-tags*:: + do not throw an error if there are undefined tags in the format string, + print "." instead + +*-v, --vcf-list* 'FILE':: + process multiple VCFs listed in the file + +==== Format: + + %CHROM The CHROM column (similarly also other columns: POS, ID, REF, ALT, QUAL, FILTER) + %INFO/TAG Any tag in the INFO column + %TYPE Variant type (REF, SNP, MNP, INDEL, BND, OTHER) + %MASK Indicates presence of the site in other files (with multiple files) + %TAG{INT} Curly brackets to subscript vectors (0-based) + %FIRST_ALT Alias for %ALT{0} + [] Format fields must be enclosed in brackets to loop over all samples + %GT Genotype (e.g. 0/1) + %TBCSQ Translated FORMAT/BCSQ. See the csq command above for explanation and examples. + %TGT Translated genotype (e.g. C/A) + %IUPACGT Genotype translated to IUPAC ambiguity codes (e.g. M instead of C/A) + %LINE Prints the whole line + %SAMPLE Sample name + %POS0 POS in 0-based coordinates + %END End position of the REF allele + %END0 End position of the REF allele in 0-based cordinates + \n new line + \t tab character + + Everything else is printed verbatim. + +==== Examples: + + # Print chromosome, position, ref allele and the first alternate allele + bcftools query -f '%CHROM %POS %REF %ALT{0}\n' file.vcf.gz + + # Similar to above, but use tabs instead of spaces, add sample name and genotype + bcftools query -f '%CHROM\t%POS\t%REF\t%ALT[\t%SAMPLE=%GT]\n' file.vcf.gz + + # Print FORMAT/GT fields followed by FORMAT/GT fields + bcftools query -f 'GQ:[ %GQ] \t GT:[ %GT]\n' file.vcf + + # Make a BED file: chr, pos (0-based), end pos (1-based), id + bcftools query -f'%CHROM\t%POS0\t%END\t%ID\n' file.bcf + +[[reheader]] +=== bcftools reheader ['OPTIONS'] 'file.vcf.gz' +Modify header of VCF/BCF files, change sample names. + +*-h, --header* 'FILE':: + new VCF header + +*-o, --output* 'FILE':: + see *<>* + +*-s, --samples* 'FILE':: + new sample names, one name per line, in the same order as they appear + in the VCF file. Alternatively, only samples which need to be renamed + can be listed as "old_name new_name\n" pairs separated by whitespaces, + each on a separate line. If a sample name contains spaces, the + spaces can be escaped using the backslash character, for example + "Not\ a\ good\ sample\ name". + + +[[roh]] +=== bcftools roh ['OPTIONS'] 'file.vcf.gz' +A program for detecting runs of homo/autozygosity. Only bi-allelic sites +are considered. + +==== The HMM model: +-------------------------------------- +Notation: + D = Data, AZ = autozygosity, HW = Hardy-Weinberg (non-autozygosity), + f = non-ref allele frequency + +Emission probabilities: + oAZ = P_i(D|AZ) = (1-f)*P(D|RR) + f*P(D|AA) + oHW = P_i(D|HW) = (1-f)^2 * P(D|RR) + f^2 * P(D|AA) + 2*f*(1-f)*P(D|RA) + +Transition probabilities: + tAZ = P(AZ|HW) .. from HW to AZ, the -a parameter + tHW = P(HW|AZ) .. from AZ to HW, the -H parameter + + ci = P_i(C) .. probability of cross-over at site i, from genetic map + AZi = P_i(AZ) .. probability of site i being AZ/non-AZ, scaled so that AZi+HWi = 1 + HWi = P_i(HW) + + P_{i+1}(AZ) = oAZ * max[(1 - tAZ * ci) * AZ{i-1} , tAZ * ci * (1-AZ{i-1})] + P_{i+1}(HW) = oHW * max[(1 - tHW * ci) * (1-AZ{i-1}) , tHW * ci * AZ{i-1}] + +-------------------------------------- + +==== General Options: + +*--AF-dflt* 'FLOAT':: + in case allele frequency is not known, use the 'FLOAT'. By default, sites where + allele frequency cannot be determined, or is 0, are skipped. + +*--AF-tag* 'TAG':: + use the specified INFO tag 'TAG' as an allele frequency estimate + instead of the default AC and AN tags. Sites which do not have 'TAG' + will be skipped. + +*--AF-file* 'FILE':: + Read allele frequencies from a tab-delimited file containing + the columns: CHROM\tPOS\tREF,ALT\tAF. The file can be compressed with + *bgzip* and indexed with tabix -s1 -b2 -e2. Sites which are not present in + the 'FILE' or have different reference or alternate allele will be skipped. + Note that such a file can be easily created from a VCF using: +---- + bcftools query -f'%CHROM\t%POS\t%REF,%ALT\t%INFO/TAG\n' file.vcf | bgzip -c > freqs.tab.gz +---- + +*-b, --buffer-size* 'INT'[,'INT']:: + when the entire many-sample file cannot fit into memory, a sliding + buffer approach can be used. The first value is the number of sites + to keep in memory. If negative, it is interpreted as the maximum + memory to use, in MB. The second, optional, value sets the number + of overlapping sites. The default overlap is set to roughly 1% of + the buffer size. + +*-e, --estimate-AF* ['TAG',]'FILE':: + estimate the allele frequency by recalculating INFO/AC and INFO/AN on + the fly, using the specified 'TAG' which can be either FORMAT/GT ("GT") + or FORMAT/PL ("PL"). If 'TAG' is not given, "GT" is assumed. Either all + samples ("-") or samples listed in 'FILE' will be included. For example, + use "PL,-" to estimate AF from FORMAT/PL of all samples. + If neither *-e* nor the other *--AF-...* options are given, the allele frequency is + estimated from AC and AN counts which are already present in the INFO field. + +*-G, --GTs-only* 'FLOAT':: + use genotypes (FORMAT/GT fields) ignoring genotype likelihoods (FORMAT/PL), + setting PL of unseen genotypes to 'FLOAT'. Safe value to use is 30 to + account for GT errors. + +*-I, --skip-indels*:: + skip indels as their genotypes are usually enriched for errors + +*-m, --genetic-map* 'FILE':: + genetic map in the format required also by IMPUTE2. Only the first and + third column are used (position and Genetic_Map(cM)). The 'FILE' can + be a single file or a file mask, where string "{CHROM}" is replaced with + chromosome name. + +*-M, --rec-rate* 'FLOAT':: + constant recombination rate per bp. In combination with *--genetic-map*, + the *--rec-rate* parameter is interpreted differently, as 'FLOAT'-fold increase of + transition probabilities, which allows the model to become more sensitive + yet still account for recombination hotspots. Note that also the range + of the values is therefore different in both cases: normally the + parameter will be in the range (1e-3,1e-9) but with *--genetic-map* + it will be in the range (10,1000). + +*-o, --output* 'FILE':: + Write output to the 'FILE', by default the output is printed on stdout + +*-O, --output-type* 's'|'r'['z']:: + Generate per-site output ('s') or per-region output ('r'). By default + both types are printed and the output is uncompressed. Add 'z' for + a compressed output. + +*-r, --regions* 'chr'|'chr:pos'|'chr:from-to'|'chr:from-'[,...]:: + see *<>* + +*-R, --regions-file* 'file':: + see *<>* + +*-s, --samples* 'LIST':: + see *<>* + +*-S, --samples-file* 'FILE':: + see *<>* + +*-t, --targets* 'chr'|'chr:pos'|'chr:from-to'|'chr:from-'[,...]:: + see *<>* + +*-T, --targets-file* 'file':: + see *<>* + +==== HMM Options: + +*-a, --hw-to-az* 'FLOAT':: + P(AZ|HW) transition probability from AZ (autozygous) to HW (Hardy-Weinberg) state + +*-H, --az-to-hw* 'FLOAT':: + P(HW|AZ) transition probability from HW to AZ state + +*-V, --viterbi-training* 'FLOAT':: + estimate HMM parameters using Baum-Welch algorithm, using the convergence threshold + 'FLOAT', e.g. 1e-10 (experimental) + + + +[[stats]] +=== bcftools stats ['OPTIONS'] 'A.vcf.gz' ['B.vcf.gz'] +Parses VCF or BCF and produces text file stats which is suitable for machine +processing and can be plotted using *<>*. When two files are given, +the program generates separate stats for intersection and the complements. By +default only sites are compared, *-s*/*-S* must given to include also sample +columns. +When one VCF file is specified on the command line, then stats by non-reference allele +frequency, depth distribution, stats by quality and per-sample counts, singleton stats, +etc. are printed. +When two VCF files are given, then stats such as concordance (Genotype concordance by +non-reference allele frequency, Genotype concordance by sample, Non-Reference Discordance) +and correlation are also printed. Per-site discordance (PSD) is also printed in *--verbose* mode. + +*--af-bins* 'LIST'|'FILE':: + comma separated list of allele frequency bins (e.g. 0.1,0.5,1) + or a file listing the allele frequency bins one per line (e.g. 0.1\n0.5\n1) + +*--af-tag* 'TAG':: + allele frequency INFO tag to use for binning. By default the allele frequency is + estimated from AC/AN, if available, or directly from the genotypes (GT) if not. + +*-1, --1st-allele-only*:: + consider only the 1st alternate allele at multiallelic sites + +*-c, --collapse* 'snps'|'indels'|'both'|'all'|'some'|'none':: + see *<>* + +*-d, --depth* 'INT','INT','INT':: + ranges of depth distribution: min, max, and size of the bin + +*--debug*:: + produce verbose per-site and per-sample output + +*-e, --exclude* 'EXPRESSION':: + exclude sites for which 'EXPRESSION' is true. For valid expressions see + *<>*. + +*-E, --exons* 'file.gz':: + tab-delimited file with exons for indel frameshifts statistics. The columns + of the file are CHR, FROM, TO, with 1-based, inclusive, positions. The file + is BGZF-compressed and indexed with tabix +---- + tabix -s1 -b2 -e3 file.gz +---- + +*-f, --apply-filters* 'LIST':: + see *<>* + +*-F, --fasta-ref* 'ref.fa':: + faidx indexed reference sequence file to determine INDEL context + +*-i, --include* 'EXPRESSION':: + include only sites for which 'EXPRESSION' is true. For valid expressions see + *<>*. + +*-I, --split-by-ID*:: + collect stats separately for sites which have the ID column set ("known + sites") or which do not have the ID column set ("novel sites"). + +*-r, --regions* 'chr'|'chr:pos'|'chr:from-to'|'chr:from-'[,...]:: + see *<>* + +*-R, --regions-file* 'file':: + see *<>* + +*-s, --samples* 'LIST':: + see *<>* + +*-S, --samples-file* 'FILE':: + see *<>* + +*-t, --targets* 'chr'|'chr:pos'|'chr:from-to'|'chr:from-'[,...]:: + see *<>* + +*-T, --targets-file* 'file':: + see *<>* + +*-u, --user-tstv* '':: + collect Ts/Tv stats for any tag using the given binning [0:1:100] + +*-v, --verbose*:: + produce verbose per-site and per-sample output + + +[[view]] +=== bcftools view ['OPTIONS'] 'file.vcf.gz' ['REGION' [...]] +View, subset and filter VCF or BCF files by position and filtering expression. +Convert between VCF and BCF. Former *bcftools subset*. + +==== Output options + +*-G, --drop-genotypes*:: + drop individual genotype information (after subsetting if *-s* option is set) + +*-h, --header-only*:: + output the VCF header only + +*-H, --no-header*:: + suppress the header in VCF output + +*-l, --compression-level* ['0-9']:: + compression level. 0 stands for uncompressed, 1 for best speed and 9 for + best compression. + +*--no-version*:: + see *<>* + +*-O, --output-type* 'b'|'u'|'z'|'v':: + see *<>* + +*-o, --output-file* 'FILE': + output file name. If not present, the default is to print to standard output (stdout). + +*-r, --regions* 'chr'|'chr:pos'|'chr:from-to'|'chr:from-'[,...]:: + see *<>* + +*-R, --regions-file* 'file':: + see *<>* + +*-t, --targets* 'chr'|'chr:pos'|'chr:from-to'|'chr:from-'[,...]:: + see *<>* + +*-T, --targets-file* 'file':: + see *<>* + +*--threads* 'INT':: + see *<>* + + +==== Subset options: +*-a, --trim-alt-alleles*:: + trim alternate alleles not seen in subset. Type A, G and R INFO and FORMAT + fields will also be trimmed + +*--force-samples*:: + only warn about unknown subset samples + +*-I, --no-update*:: + do not (re)calculate INFO fields for the subset (currently INFO/AC and INFO/AN) + +*-s, --samples* 'LIST':: + see *<>* + +*-S, --samples-file* 'FILE':: + see *<>* + + +==== Filter options: +Note that filter options below dealing with counting the number of alleles +will, for speed, first check for the values of AC and AN in the INFO column to +avoid parsing all the genotype (FORMAT/GT) fields in the VCF. This means +that a filter like '--min-af 0.1' will be based `AC/AN' where AC and AN come +from either INFO/AC and INFO/AN if available or FORMAT/GT if not. It will not +filter on another field like INFO/AF. The '--include' and '--exclude' filter +expressions should instead be used to explicitly filter based on fields in +the INFO column, e.g. '--exclude AF<0.1'. + +*-c, --min-ac* 'INT'[':nref'|':alt1'|':minor'|':major'|:'nonmajor']:: + minimum allele count (INFO/AC) of sites to be printed. + Specifying the type of allele is optional and can be set to + non-reference ('nref', the default), 1st alternate ('alt1'), the least + frequent ('minor'), the most frequent ('major') or sum of all but the + most frequent ('nonmajor') alleles. + +*-C, --max-ac* 'INT'[':nref'|':alt1'|':minor'|:'major'|:'nonmajor']:: + maximum allele count (INFO/AC) of sites to be printed. + Specifying the type of allele is optional and can be set to + non-reference ('nref', the default), 1st alternate ('alt1'), the least + frequent ('minor'), the most frequent ('major') or sum of all but the + most frequent ('nonmajor') alleles. + +*-e, --exclude* 'EXPRESSION':: + exclude sites for which 'EXPRESSION' is true. For valid expressions see + *<>*. + +*-f, --apply-filters* 'LIST':: + see *<>* + +*-g, --genotype* [^]['hom'|'het'|'miss']:: + include only sites with one or more homozygous ('hom'), heterozygous + ('het') or missing ('miss') genotypes. When prefixed with '^', the logic + is reversed; thus '^het' excludes sites with heterozygous genotypes. + +*-i, --include* 'EXPRESSION':: + include sites for which 'EXPRESSION' is true. For valid expressions see + *<>*. + +*-k, --known*:: + print known sites only (ID column is not ".") + +*-m, --min-alleles* 'INT':: + print sites with at least 'INT' alleles listed in REF and ALT columns + +*-M, --max-alleles* 'INT':: + print sites with at most 'INT' alleles listed in REF and ALT columns. + Use *-m2 -M2 -v snps* to only view biallelic SNPs. + +*-n, --novel*:: + print novel sites only (ID column is ".") + +*-p, --phased*:: + print sites where all samples are phased. Haploid genotypes are + considered phased. Missing genotypes considered unphased unless the + phased bit is set. + +*-P, --exclude-phased*:: + exclude sites where all samples are phased + +*-q, --min-af* 'FLOAT'[':nref'|':alt1'|':minor'|':major'|':nonmajor']:: + minimum allele frequency (INFO/AC / INFO/AN) of sites to be printed. + Specifying the type of allele is optional and can be set to + non-reference ('nref', the default), 1st alternate ('alt1'), the least + frequent ('minor'), the most frequent ('major') or sum of all but the + most frequent ('nonmajor') alleles. + +*-Q, --max-af* 'FLOAT'[':nref'|':alt1'|':minor'|':major'|':nonmajor']:: + maximum allele frequency (INFO/AC / INFO/AN) of sites to be printed. + Specifying the type of allele is optional and can be set to + non-reference ('nref', the default), 1st alternate ('alt1'), the least + frequent ('minor'), the most frequent ('major') or sum of all but the + most frequent ('nonmajor') alleles. + +*-u, --uncalled*:: + print sites without a called genotype + +*-U, --exclude-uncalled*:: + exclude sites without a called genotype + +*-v, --types* 'snps'|'indels'|'mnps'|'other':: + comma-separated list of variant types to select. Site is selected if + any of the ALT alleles is of the type requested. Types are determined + by comparing the REF and ALT alleles in the VCF record not INFO tags + like INFO/INDEL or INFO/VT. Use *--include* to select based on INFO + tags. + +*-V, --exclude-types* 'snps'|'indels'|'mnps'|'ref'|'bnd'|'other':: + comma-separated list of variant types to exclude. Site is excluded if + any of the ALT alleles is of the type requested. Types are determined + by comparing the REF and ALT alleles in the VCF record not INFO tags + like INFO/INDEL or INFO/VT. Use *--exclude* to exclude based on INFO tags. + +*-x, --private*:: + print sites where only the subset samples carry an non-reference allele. + Requires *--samples* or *--samples-file*. + +*-X, --exclude-private*:: + exclude sites where only the subset samples carry an non-reference allele + +[[help]] +=== bcftools help ['COMMAND'] | bcftools --help ['COMMAND'] +Display a brief usage message listing the bcftools commands available. +If the name of a command is also given, e.g., bcftools help view, the detailed +usage message for that particular command is displayed. + +[[version]] +=== bcftools ['--version'|'-v'] +Display the version numbers and copyright information for bcftools and the +important libraries used by bcftools. + +[[version-only]] +=== bcftools ['--version-only'] +Display the full bcftools version number in a machine-readable format. + + +[[expressions]] +EXPRESSIONS +----------- + +These filtering expressions are accepted by most of the commands. + +.Valid expressions may contain: + +* numerical constants, string constants, file names + + 1, 1.0, 1e-4 + "String" + @file_name + + +* arithmetic operators + + +,*,-,/ + +* comparison operators + + == (same as =), >, >=, <=, <, != + +* regex operators "\~" and its negation "!~". The expressions are case sensitive unless "/i" is added. + + INFO/HAYSTACK ~ "needle" + INFO/HAYSTACK ~ "NEEDless/i" + +* parentheses + + (, ) + +* logical operators + + && (same as &), ||, | + +* INFO tags, FORMAT tags, column names + + INFO/DP or DP + FORMAT/DV, FMT/DV, or DV + FILTER, QUAL, ID, POS, REF, ALT[0] + +* 1 (or 0) to test the presence (or absence) of a flag + + FlagA=1 && FlagB=0 + +* "." to test missing values + + DP=".", DP!=".", ALT="." + +* missing genotypes can be matched regardless of phase and ploidy (".|.", "./.", ".") +using these expressions + + GT~"\.", GT!~"\." + +* missing genotypes can be matched including the phase and ploidy (".|.", "./.", ".") +using these expressions + + GT=".|.", GT="./.", GT="." + +* TYPE for variant type in REF,ALT columns (indel,snp,mnp,ref,bnd,other). Use the regex +operator "\~" to require at least one allele of the given type or the equal sign "=" +to require that all alleles are of the given type. Compare + + TYPE="snp" + TYPE~"snp" + TYPE!="snp" + TYPE!~"snp" + +* array subscripts, "*" for any field + + (DP4[0]+DP4[1])/(DP4[2]+DP4[3]) > 0.3 + DP4[*] == 0 + CSQ[*] ~ "missense_variant.*deleterious" + +* function on FORMAT tags (over samples) and INFO tags (over vector fields) + + MAX, MIN, AVG, SUM, STRLEN, ABS + +* variables calculated on the fly if not present: number of alternate alleles; +number of samples; count of alternate alleles; minor allele count (similar to +AC but is always smaller than 0.5); frequency of alternate alleles (AF=AC/AN); +frequency of minor alleles (MAF=MAC/AN); number of alleles in called genotypes + + N_ALT, N_SAMPLES, AC, MAC, AF, MAF, AN + + +.Notes: + +* String comparisons and regular expressions are case-insensitive +* If the subscript "\*" is used in regular expression search, the +whole field is treated as one string. For example, the regex STR[*]~"B,C" will be +true for the string vector INFO/STR=AB,CD. +* Variables and function names are case-insensitive, but not tag names. For example, +"qual" can be used instead of "QUAL", "strlen()" instead of "STRLEN()" , but +not "dp" instead of "DP". + + +*Examples:* + +-- + MIN(DV)>5 + + MIN(DV/DP)>0.3 + + MIN(DP)>10 & MIN(DV)>3 + + FMT/DP>10 & FMT/GQ>10 .. both conditions must be satisfied within one sample + + FMT/DP>10 && FMT/GQ>10 .. the conditions can be satisfied in different samples + + QUAL>10 | FMT/GQ>10 .. selects only GQ>10 samples + + QUAL>10 || FMT/GQ>10 .. selects all samples at QUAL>10 sites + + TYPE="snp" && QUAL>=10 && (DP4[2]+DP4[3] > 2) + + MIN(DP)>35 && AVG(GQ)>50 + + ID=@file .. selects lines with ID present in the file + + ID!=@~/file .. skip lines with ID present in the ~/file + + MAF[0]<0.05 .. select rare variants at 5% cutoff + + POS>=100 .. restrict your range query, e.g. 20:100-200 to strictly sites with POS in that range. + +-- + +*Shell expansion:* + +Note that expressions must often be quoted because some characters +have special meaning in the shell. +An example of expression enclosed in single quotes which cause +that the whole expression is passed to the program as intended: + +-- + bcftools view -i '%ID!="." & MAF[0]<0.01' +-- + +Please refer to the documentation of your shell for details. + + +SCRIPTS AND OPTIONS +------------------- + +[[plot-vcfstats]] +=== plot-vcfstats ['OPTIONS'] 'file.vchk' [...] +Script for processing output of *<>*. It can merge +results from multiple outputs (useful when running the stats for each +chromosome separately), plots graphs and creates a PDF presentation. + +*-m, --merge*:: + Merge vcfstats files to STDOUT, skip plotting. + +*-p, --prefix* 'DIR':: + The output directory. This directory will be created if it does not exist. + +*-P, --no-PDF*:: + Skip the PDF creation step. + +*-r, --rasterize*:: + Rasterize PDF images for faster rendering. + +*-s, --sample-names*:: + Use sample names for xticks rather than numeric IDs. + +*-t, --title* 'STRING':: + Identify files by these titles in plots. The option can be given multiple + times, for each ID in the *<>* output. If not + present, the script will use abbreviated source file names for the titles. + +*-T, --main-title* 'STRING':: + Main title for the PDF. + + +PERFORMANCE +----------- +HTSlib was designed with BCF format in mind. When parsing VCF files, all records +are internally converted into BCF representation. Simple operations, like removing +a single column from a VCF file, can be therefore done much faster with standard +UNIX commands, such as *awk* or *cut*. +Therefore it is recommended to use BCF as input/output format whenever possible to avoid +large overhead of the VCF -> BCF -> VCF conversion. + + +BUGS +---- +Please report any bugs you encounter on the github website: + + +AUTHORS +------- +Heng Li from the Sanger Institute wrote the original C version of htslib, +samtools and bcftools. Bob Handsaker from the Broad Institute implemented the +BGZF library. Petr Danecek, Shane McCarthy and John Marshall are maintaining +and further developing bcftools. Many other people contributed to the program +and to the file format specifications, both directly and indirectly by +providing patches, testing and reporting bugs. We thank them all. + + +RESOURCES +--------- +BCFtools GitHub website: + +Samtools GitHub website: + +HTSlib GitHub website: + +File format specifications: + +BCFtools documentation: + +BCFtools wiki page: + + +COPYING +------- +The MIT/Expat License or GPL License, see the LICENSE document for details. +Copyright (c) Genome Research Ltd. + diff --git a/doc/docbook-xsl.css b/doc/docbook-xsl.css new file mode 100644 index 0000000..0b83c64 --- /dev/null +++ b/doc/docbook-xsl.css @@ -0,0 +1,355 @@ +/* + CSS stylesheet for XHTML produced by DocBook XSL stylesheets. +*/ + +body { + /* font-family: Georgia,serif; */ +} + +code, pre { + /* font-family: "Courier New", Courier, monospace; */ +} + +span.strong { + font-weight: bold; +} + +body blockquote { + margin-top: .75em; + line-height: 1.5; + margin-bottom: .75em; +} + +html body { + margin: 1em 5% 1em 10%; + /*x line-height: 1.2; */ +} + +body div { + margin: 0; +} + +h1, h2, h3, h4, h5, h6 +{ + /*x color: #527bbd; */ + color: #FF8800; + /* font-family: Arial,Helvetica,sans-serif; 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} +span.blue-background { background: blue; } +span.fuchsia-background { background: fuchsia; } +span.gray-background { background: gray; } +span.green-background { background: green; } +span.lime-background { background: lime; } +span.maroon-background { background: maroon; } +span.navy-background { background: navy; } +span.olive-background { background: olive; } +span.purple-background { background: purple; } +span.red-background { background: red; } +span.silver-background { background: silver; } +span.teal-background { background: teal; } +span.white-background { background: white; } +span.yellow-background { background: yellow; } + +span.big { font-size: 2em; } +span.small { font-size: 0.6em; } + +span.underline { text-decoration: underline; } +span.overline { text-decoration: overline; } +span.line-through { text-decoration: line-through; } diff --git a/em.c b/em.c new file mode 100644 index 0000000..a976f22 --- /dev/null +++ b/em.c @@ -0,0 +1,259 @@ +/* em.c -- mathematical functions. + + Copyright (C) 2010, 2011 Broad Institute. + Portions copyright (C) 2013 Genome Research Ltd. + + Author: Heng Li + +Permission is hereby granted, free of charge, to any person obtaining a copy +of this software and associated documentation files (the "Software"), to deal +in the Software without restriction, including without limitation the rights +to use, copy, modify, merge, publish, distribute, sublicense, and/or sell +copies of the Software, and to permit persons to whom the Software is +furnished to do so, subject to the following conditions: + +The above copyright notice and this permission notice shall be included in +all copies or substantial portions of the Software. + +THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE +AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER +LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, +OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN +THE SOFTWARE. */ + +#include +#include +#include +#include +#include "kmin.h" +#include "call.h" + +#define ITER_MAX 50 +#define ITER_TRY 10 +#define EPS 1e-5 + +extern double kf_gammaq(double, double); + +/* + Generic routines + */ + +// estimate site allele frequency in a very naive and inaccurate way +static double est_freq(int n, const double *pdg) +{ + int i, gcnt[3], tmp1; + // get a rough estimate of the genotype frequency + gcnt[0] = gcnt[1] = gcnt[2] = 0; + for (i = 0; i < n; ++i) { + const double *p = pdg + i * 3; + if (p[0] != 1. || p[1] != 1. || p[2] != 1.) { + int which = p[0] > p[1]? 0 : 1; + which = p[which] > p[2]? which : 2; + ++gcnt[which]; + } + } + tmp1 = gcnt[0] + gcnt[1] + gcnt[2]; + return (tmp1 == 0)? -1.0 : (.5 * gcnt[1] + gcnt[2]) / tmp1; +} + +/* + Single-locus EM + */ + +typedef struct { + int beg, end; + const double *pdg; +} minaux1_t; + +static double prob1(double f, void *data) +{ + minaux1_t *a = (minaux1_t*)data; + double p = 1., l = 0., f3[3]; + int i; +// printf("brent %lg\n", f); + if (f < 0 || f > 1) return 1e300; + f3[0] = (1.-f)*(1.-f); f3[1] = 2.*f*(1.-f); f3[2] = f*f; + for (i = a->beg; i < a->end; ++i) { + const double *pdg = a->pdg + i * 3; + p *= pdg[0] * f3[0] + pdg[1] * f3[1] + pdg[2] * f3[2]; + if (p < 1e-200) l -= log(p), p = 1.; + } + return l - log(p); +} + +// one EM iteration for allele frequency estimate +static double freq_iter(double *f, const double *_pdg, int beg, int end) +{ + double f0 = *f, f3[3], err; + int i; +// printf("em %lg\n", *f); + f3[0] = (1.-f0)*(1.-f0); f3[1] = 2.*f0*(1.-f0); f3[2] = f0*f0; + for (i = beg, f0 = 0.; i < end; ++i) { + const double *pdg = _pdg + i * 3; + f0 += (pdg[1] * f3[1] + 2. * pdg[2] * f3[2]) + / (pdg[0] * f3[0] + pdg[1] * f3[1] + pdg[2] * f3[2]); + } + f0 /= (end - beg) * 2; + err = fabs(f0 - *f); + *f = f0; + return err; +} + +/* The following function combines EM and Brent's method. When the signal from + * the data is strong, EM is faster but sometimes, EM may converge very slowly. + * When this happens, we switch to Brent's method. The idea is learned from + * Rasmus Nielsen. + */ +static double freqml(double f0, int beg, int end, const double *pdg) +{ + int i; + double f; + for (i = 0, f = f0; i < ITER_TRY; ++i) + if (freq_iter(&f, pdg, beg, end) < EPS) break; + if (i == ITER_TRY) { // haven't converged yet; try Brent's method + minaux1_t a; + a.beg = beg; a.end = end; a.pdg = pdg; + kmin_brent(prob1, f0 == f? .5*f0 : f0, f, (void*)&a, EPS, &f); + } + return f; +} + +// one EM iteration for genotype frequency estimate +static double g3_iter(double g[3], const double *_pdg, int beg, int end) +{ + double err, gg[3]; + int i; + gg[0] = gg[1] = gg[2] = 0.; +// printf("%lg,%lg,%lg\n", g[0], g[1], g[2]); + for (i = beg; i < end; ++i) { + double sum, tmp[3]; + const double *pdg = _pdg + i * 3; + tmp[0] = pdg[0] * g[0]; tmp[1] = pdg[1] * g[1]; tmp[2] = pdg[2] * g[2]; + sum = (tmp[0] + tmp[1] + tmp[2]) * (end - beg); + gg[0] += tmp[0] / sum; gg[1] += tmp[1] / sum; gg[2] += tmp[2] / sum; + } + err = fabs(gg[0] - g[0]) > fabs(gg[1] - g[1])? fabs(gg[0] - g[0]) : fabs(gg[1] - g[1]); + err = err > fabs(gg[2] - g[2])? err : fabs(gg[2] - g[2]); + g[0] = gg[0]; g[1] = gg[1]; g[2] = gg[2]; + return err; +} + +// perform likelihood ratio test +static double lk_ratio_test(int n, int n1, const double *pdg, double f3[3][3]) +{ + double r; + int i; + for (i = 0, r = 1.; i < n1; ++i) { + const double *p = pdg + i * 3; + r *= (p[0] * f3[1][0] + p[1] * f3[1][1] + p[2] * f3[1][2]) + / (p[0] * f3[0][0] + p[1] * f3[0][1] + p[2] * f3[0][2]); + } + for (; i < n; ++i) { + const double *p = pdg + i * 3; + r *= (p[0] * f3[2][0] + p[1] * f3[2][1] + p[2] * f3[2][2]) + / (p[0] * f3[0][0] + p[1] * f3[0][1] + p[2] * f3[0][2]); + } + return r; +} + +// x[0]: ref frequency +// x[1..3]: alt-alt, alt-ref, ref-ref frequenc +// x[4]: HWE P-value +// x[5..6]: group1 freq, group2 freq +// x[7]: 1-degree P-value +// x[8]: 2-degree P-value +int bcf_em1(call_t *call, const bcf1_t *rec, int n1, int flag, double x[10]) +{ + double *pdg; + int i, n; //, n2; + if (rec->n_allele < 2) return -1; // one allele only + // initialization + if (n1 < 0 || n1 > rec->n_sample) n1 = 0; + if (flag & 1<<7) flag |= 7<<5; // compute group freq if LRT is required + if (flag & 0xf<<1) flag |= 0xf<<1; + n = rec->n_sample; //n2 = n - n1; + pdg = call->pdg; + if (pdg == 0) return -1; + for (i = 0; i < 10; ++i) x[i] = -1.; // set to negative + { + if ((x[0] = est_freq(n, pdg)) < 0.) return -1; // no data + x[0] = freqml(x[0], 0, n, pdg); + } + if (flag & (0xf<<1|3<<8)) { // estimate the genotype frequency and test HWE + double *g = x + 1, f3[3], r; + f3[0] = g[0] = (1 - x[0]) * (1 - x[0]); + f3[1] = g[1] = 2 * x[0] * (1 - x[0]); + f3[2] = g[2] = x[0] * x[0]; + for (i = 0; i < ITER_MAX; ++i) + if (g3_iter(g, pdg, 0, n) < EPS) break; + // Hardy-Weinberg equilibrium (HWE) + for (i = 0, r = 1.; i < n; ++i) { + double *p = pdg + i * 3; + r *= (p[0] * g[0] + p[1] * g[1] + p[2] * g[2]) / (p[0] * f3[0] + p[1] * f3[1] + p[2] * f3[2]); + } + x[4] = kf_gammaq(.5, log(r)); + } + if ((flag & 7<<5) && n1 > 0 && n1 < n) { // group frequency + x[5] = freqml(x[0], 0, n1, pdg); + x[6] = freqml(x[0], n1, n, pdg); + } + if ((flag & 1<<7) && n1 > 0 && n1 < n) { // 1-degree P-value + double f[3], f3[3][3], tmp; + f[0] = x[0]; f[1] = x[5]; f[2] = x[6]; + for (i = 0; i < 3; ++i) + f3[i][0] = (1-f[i])*(1-f[i]), f3[i][1] = 2*f[i]*(1-f[i]), f3[i][2] = f[i]*f[i]; + tmp = log(lk_ratio_test(n, n1, pdg, f3)); + if (tmp < 0) tmp = 0; + x[7] = kf_gammaq(.5, tmp); + } + if ((flag & 3<<8) && n1 > 0 && n1 < n) { // 2-degree P-value + double g[3][3], tmp; + for (i = 0; i < 3; ++i) memcpy(g[i], x + 1, 3 * sizeof(double)); + for (i = 0; i < ITER_MAX; ++i) + if (g3_iter(g[1], pdg, 0, n1) < EPS) break; + for (i = 0; i < ITER_MAX; ++i) + if (g3_iter(g[2], pdg, n1, n) < EPS) break; + tmp = log(lk_ratio_test(n, n1, pdg, g)); + if (tmp < 0) tmp = 0; + x[8] = kf_gammaq(1., tmp); + } + return 0; +} + +/* + Two-locus EM (LD) + */ + +#define _G1(h, k) ((h>>1&1) + (k>>1&1)) +#define _G2(h, k) ((h&1) + (k&1)) + +#if 0 +// 0: the previous site; 1: the current site +static int pair_freq_iter(int n, double *pdg[2], double f[4]) +{ + double ff[4]; + int i, k, h; +// printf("%lf,%lf,%lf,%lf\n", f[0], f[1], f[2], f[3]); + memset(ff, 0, 4 * sizeof(double)); + for (i = 0; i < n; ++i) { + double *p[2], sum, tmp; + p[0] = pdg[0] + i * 3; p[1] = pdg[1] + i * 3; + for (k = 0, sum = 0.; k < 4; ++k) + for (h = 0; h < 4; ++h) + sum += f[k] * f[h] * p[0][_G1(k,h)] * p[1][_G2(k,h)]; + for (k = 0; k < 4; ++k) { + tmp = f[0] * (p[0][_G1(0,k)] * p[1][_G2(0,k)] + p[0][_G1(k,0)] * p[1][_G2(k,0)]) + + f[1] * (p[0][_G1(1,k)] * p[1][_G2(1,k)] + p[0][_G1(k,1)] * p[1][_G2(k,1)]) + + f[2] * (p[0][_G1(2,k)] * p[1][_G2(2,k)] + p[0][_G1(k,2)] * p[1][_G2(k,2)]) + + f[3] * (p[0][_G1(3,k)] * p[1][_G2(3,k)] + p[0][_G1(k,3)] * p[1][_G2(k,3)]); + ff[k] += f[k] * tmp / sum; + } + } + for (k = 0; k < 4; ++k) f[k] = ff[k] / (2 * n); + return 0; +} +#endif + + diff --git a/filter.c b/filter.c new file mode 100644 index 0000000..463028f --- /dev/null +++ b/filter.c @@ -0,0 +1,1867 @@ +/* filter.c -- filter expressions. + + Copyright (C) 2013-2015 Genome Research Ltd. + + Author: Petr Danecek + +Permission is hereby granted, free of charge, to any person obtaining a copy +of this software and associated documentation files (the "Software"), to deal +in the Software without restriction, including without limitation the rights +to use, copy, modify, merge, publish, distribute, sublicense, and/or sell +copies of the Software, and to permit persons to whom the Software is +furnished to do so, subject to the following conditions: + +The above copyright notice and this permission notice shall be included in +all copies or substantial portions of the Software. + +THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE +AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER +LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, +OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN +THE SOFTWARE. */ + +#include +#include +#include +#include +#include +#include +#include +#include +#include "filter.h" +#include "bcftools.h" +#include +#include + +#ifndef __FUNCTION__ +# define __FUNCTION__ __func__ +#endif + +uint64_t bcf_double_missing = 0x7ff0000000000001; +uint64_t bcf_double_vector_end = 0x7ff0000000000002; +static inline void bcf_double_set(double *ptr, uint64_t value) +{ + union { uint64_t i; double d; } u; + u.i = value; + *ptr = u.d; +} +static inline int bcf_double_test(double d, uint64_t value) +{ + union { uint64_t i; double d; } u; + u.d = d; + return u.i==value ? 1 : 0; +} +#define bcf_double_set_vector_end(x) bcf_double_set(&(x),bcf_double_vector_end) +#define bcf_double_set_missing(x) bcf_double_set(&(x),bcf_double_missing) +#define bcf_double_is_vector_end(x) bcf_double_test((x),bcf_double_vector_end) +#define bcf_double_is_missing(x) bcf_double_test((x),bcf_double_missing) + + +typedef struct _token_t +{ + // read-only values, same for all VCF lines + int tok_type; // one of the TOK_* keys below + char *key; // set only for string constants, otherwise NULL + char *tag; // for debugging and printout only, VCF tag name + double threshold; // filtering threshold + int hdr_id, type; // BCF header lookup ID and one of BCF_HT_* types + int idx; // 0-based index to VCF vectors, -1: not a vector, -2: any field ([*]) + void (*setter)(filter_t *, bcf1_t *, struct _token_t *); + int (*comparator)(struct _token_t *, struct _token_t *, int op_type, bcf1_t *); + void *hash; // test presence of str value in the hash via comparator + regex_t *regex; // precompiled regex for string comparison + + // modified on filter evaluation at each VCF line + double *values; // In case str_value is set, values[0] is one sample's string length + char *str_value; // and values[0]*nsamples gives the total length; + int is_str, is_missing; // is_missing is set only for constants, variables are controled via nvalues + int pass_site; // -1 not applicable, 0 fails, >0 pass + uint8_t *pass_samples; // status of individual samples + int nsamples; // number of samples + int nvalues, mvalues; // number of used values, n=0 for missing values, n=1 for scalars + // for strings, total length of str_value +} +token_t; + +struct _filter_t +{ + bcf_hdr_t *hdr; + char *str; + int nfilters; + token_t *filters, **flt_stack; // filtering input tokens (in RPN) and evaluation stack + int32_t *tmpi; + float *tmpf; + int max_unpack, mtmpi, mtmpf, nsamples; +}; + + +#define TOK_VAL 0 +#define TOK_LFT 1 // ( +#define TOK_RGT 2 // ) +#define TOK_LE 3 // less or equal +#define TOK_LT 4 // less than +#define TOK_EQ 5 // equal +#define TOK_BT 6 // bigger than +#define TOK_BE 7 // bigger or equal +#define TOK_NE 8 // not equal +#define TOK_OR 9 // | +#define TOK_AND 10 // & +#define TOK_ADD 11 // + +#define TOK_SUB 12 // - +#define TOK_MULT 13 // * +#define TOK_DIV 14 // / +#define TOK_MAX 15 +#define TOK_MIN 16 +#define TOK_AVG 17 +#define TOK_AND_VEC 18 // && (operator applied in samples) +#define TOK_OR_VEC 19 // || (operator applied in samples) +#define TOK_LIKE 20 // ~ regular expression +#define TOK_NLIKE 21 // !~ regular expression +#define TOK_SUM 22 +#define TOK_ABS 23 +#define TOK_LEN 24 +#define TOK_FUNC 25 + +// 0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 +// ( ) [ < = > ] ! | & + - * / M m a A O ~ ^ S . l +static int op_prec[] = {0,1,1,5,5,5,5,5,5,2,3, 6, 6, 7, 7, 8, 8, 8, 3, 2, 5, 5, 8, 8, 8}; +#define TOKEN_STRING "x()[<=>]!|&+-*/MmaAO~^f" + +static int filters_next_token(char **str, int *len) +{ + char *tmp = *str; + while ( *tmp && isspace(*tmp) ) tmp++; + *str = tmp; + *len = 0; + + // test for doubles: d.ddde[+-]dd + if ( isdigit(*str[0]) || *str[0]=='.' ) // strtod would eat +/- + { + double HTS_UNUSED v = strtod(*str, &tmp); + if ( *str!=tmp && (!tmp[0] || !isalnum(tmp[0])) ) + { + *len = tmp - (*str); + return TOK_VAL; + } + tmp = *str; + } + + if ( !strncasecmp(tmp,"MAX(",4) ) { (*str) += 3; return TOK_MAX; } + if ( !strncasecmp(tmp,"MIN(",4) ) { (*str) += 3; return TOK_MIN; } + if ( !strncasecmp(tmp,"AVG(",4) ) { (*str) += 3; return TOK_AVG; } + if ( !strncasecmp(tmp,"SUM(",4) ) { (*str) += 3; return TOK_SUM; } + if ( !strncasecmp(tmp,"ABS(",4) ) { (*str) += 3; return TOK_ABS; } + if ( !strncasecmp(tmp,"STRLEN(",7) ) { (*str) += 6; return TOK_LEN; } + if ( !strncasecmp(tmp,"%MAX(",5) ) { (*str) += 4; return TOK_MAX; } // for backward compatibility + if ( !strncasecmp(tmp,"%MIN(",5) ) { (*str) += 4; return TOK_MIN; } // for backward compatibility + if ( !strncasecmp(tmp,"%AVG(",5) ) { (*str) += 4; return TOK_AVG; } // for backward compatibility + if ( !strncasecmp(tmp,"%SUM(",5) ) { (*str) += 4; return TOK_SUM; } // for backward compatibility + if ( !strncasecmp(tmp,"INFO/",5) ) tmp += 5; + if ( !strncasecmp(tmp,"FORMAT/",7) ) tmp += 7; + if ( !strncasecmp(tmp,"FMT/",4) ) tmp += 4; + + if ( tmp[0]=='@' ) // file name + { + while ( *tmp && !isspace(*tmp) && *tmp!='=' && *tmp!='!' ) tmp++; + *len = tmp - (*str); + return TOK_VAL; + } + + while ( tmp[0] ) + { + if ( tmp[0]=='"' ) break; + if ( tmp[0]=='\'' ) break; + if ( isspace(tmp[0]) ) break; + if ( tmp[0]=='<' ) break; + if ( tmp[0]=='>' ) break; + if ( tmp[0]=='=' ) break; + if ( tmp[0]=='!' ) break; + if ( tmp[0]=='&' ) break; + if ( tmp[0]=='|' ) break; + if ( tmp[0]=='(' ) break; + if ( tmp[0]==')' ) break; + if ( tmp[0]=='+' ) break; + // hacky: so that [*] is not split, the tokenizer does not recognise square brackets [] + if ( tmp[0]=='*' && (tmp==*str || tmp[-1]!='[') ) break; + if ( tmp[0]=='-' ) break; + if ( tmp[0]=='/' ) break; + if ( tmp[0]=='~' ) break; + tmp++; + } + if ( tmp > *str ) + { + *len = tmp - (*str); + return TOK_VAL; + } + if ( tmp[0]=='"' || tmp[0]=='\'' ) + { + int quote = tmp[0]; + tmp++; + while ( *tmp && tmp[0]!=quote ) tmp++; + if ( !*tmp ) return -1; // missing quotes + *len = tmp - (*str) + 1; + return TOK_VAL; + } + if ( tmp[0]=='!' ) + { + if ( tmp[1]=='=' ) { (*str) += 2; return TOK_NE; } + if ( tmp[1]=='~' ) { (*str) += 2; return TOK_NLIKE; } + } + if ( tmp[0]=='<' ) + { + if ( tmp[1]=='=' ) { (*str) += 2; return TOK_LE; } + (*str) += 1; return TOK_LT; + } + if ( tmp[0]=='>' ) + { + if ( tmp[1]=='=' ) { (*str) += 2; return TOK_BE; } + (*str) += 1; return TOK_BT; + } + if ( tmp[0]=='=' ) + { + if ( tmp[1]=='=' ) { (*str) += 2; return TOK_EQ; } + (*str) += 1; return TOK_EQ; + } + if ( tmp[0]=='(' ) { (*str) += 1; return TOK_LFT; } + if ( tmp[0]==')' ) { (*str) += 1; return TOK_RGT; } + if ( tmp[0]=='&' && tmp[1]=='&' ) { (*str) += 2; return TOK_AND_VEC; } + if ( tmp[0]=='|' && tmp[1]=='|' ) { (*str) += 2; return TOK_OR_VEC; } + if ( tmp[0]=='&' ) { (*str) += 1; return TOK_AND; } + if ( tmp[0]=='|' ) { (*str) += 1; return TOK_OR; } + if ( tmp[0]=='+' ) { (*str) += 1; return TOK_ADD; } + if ( tmp[0]=='-' ) { (*str) += 1; return TOK_SUB; } + if ( tmp[0]=='*' ) { (*str) += 1; return TOK_MULT; } + if ( tmp[0]=='/' ) { (*str) += 1; return TOK_DIV; } + if ( tmp[0]=='~' ) { (*str) += 1; return TOK_LIKE; } + + *len = tmp - (*str); + return TOK_VAL; +} + +static void filters_set_qual(filter_t *flt, bcf1_t *line, token_t *tok) +{ + float *ptr = &line->qual; + if ( bcf_float_is_missing(*ptr) ) + tok->nvalues = 0; + else + { + tok->values[0] = (double)line->qual; + tok->nvalues = 1; + } +} +static void filters_set_type(filter_t *flt, bcf1_t *line, token_t *tok) +{ + tok->values[0] = bcf_get_variant_types(line); + if ( !tok->values[0] ) tok->values[0] = 1; // mistake in htslib: VCF_* should start with 1 + else tok->values[0] = ((int)tok->values[0]) << 1; + tok->nvalues = 1; +} +static void filters_set_info(filter_t *flt, bcf1_t *line, token_t *tok) +{ + assert( tok->hdr_id >=0 ); + int i; + for (i=0; in_info; i++) + if ( line->d.info[i].key == tok->hdr_id ) break; + + if ( i==line->n_info ) + tok->nvalues = 0; + else if ( line->d.info[i].type==BCF_BT_CHAR ) + { + int n = line->d.info[i].len; + int m = (int)tok->values[0]; + hts_expand(char,n+1,m,tok->str_value); + memcpy(tok->str_value,line->d.info[i].vptr,n); + tok->str_value[n] = 0; + tok->values[0] = m; + tok->nvalues = n; + } + else if ( line->d.info[i].type==BCF_BT_FLOAT ) + { + if ( bcf_float_is_missing(line->d.info[i].v1.f) ) tok->nvalues = 0; + else + { + tok->values[0] = line->d.info[i].v1.f; + tok->nvalues = 1; + } + tok->str_value = NULL; + } + else + { + if ( line->d.info[i].type==BCF_BT_INT8 && line->d.info[i].v1.i==bcf_int8_missing ) tok->nvalues = 0; + else if ( line->d.info[i].type==BCF_BT_INT16 && line->d.info[i].v1.i==bcf_int16_missing ) tok->nvalues = 0; + else if ( line->d.info[i].type==BCF_BT_INT32 && line->d.info[i].v1.i==bcf_int32_missing ) tok->nvalues = 0; + else + { + tok->values[0] = line->d.info[i].v1.i; + tok->nvalues = 1; + } + tok->str_value = NULL; + } +} +static int filters_cmp_bit_and(token_t *atok, token_t *btok, int op_type, bcf1_t *line) +{ + int a = (int)(atok->nvalues?atok->values[0]:atok->threshold); + int b = (int)(btok->nvalues?btok->values[0]:btok->threshold); + if ( op_type==TOK_LIKE ) return a&b ? 1 : 0; + return a&b ? 0 : 1; +} +static int filters_cmp_filter(token_t *atok, token_t *btok, int op_type, bcf1_t *line) +{ + int i; + if ( op_type==TOK_NE ) // AND logic: none of the filters can match + { + if ( !line->d.n_flt ) + { + if ( atok->hdr_id==-1 ) return 0; // missing value + return 1; // no filter present, eval to true + } + for (i=0; id.n_flt; i++) + if ( atok->hdr_id==line->d.flt[i] ) return 0; + return 1; + } + // TOK_EQ with OR logic: at least one of the filters must match + if ( !line->d.n_flt ) + { + if ( atok->hdr_id==-1 ) return 1; + return 0; // no filter present, eval to false + } + for (i=0; id.n_flt; i++) + if ( atok->hdr_id==line->d.flt[i] ) return 1; + return 0; +} +static int filters_cmp_id(token_t *atok, token_t *btok, int op_type, bcf1_t *line) +{ + // multiple IDs not supported yet (easy to add though) + + if ( btok->hash ) + { + token_t *tmp = atok; atok = btok; btok = tmp; + } + if ( atok->hash ) + { + int ret = khash_str2int_has_key(atok->hash, line->d.id); + if ( op_type==TOK_EQ ) return ret; + return ret ? 0 : 1; + } + + if ( op_type==TOK_EQ ) return strcmp(btok->str_value,line->d.id) ? 0 : 1; + return strcmp(btok->str_value,line->d.id) ? 1 : 0; +} + +/** + * bcf_get_info_value() - get single INFO value, int64_t or double + * @line: BCF line + * @info_id: tag ID, as returned by bcf_hdr_id2int + * @ivec: 0-based index to retrieve, -1 when single value is expected + * @vptr: pointer to memory location of sufficient size to accomodate + * info_id's type + * + * The returned value is -1 if tag is not present, 0 if present but + * values is missing or ivec is out of range, and 1 on success. + */ +static int bcf_get_info_value(bcf1_t *line, int info_id, int ivec, void *value) +{ + int j; + for (j=0; jn_info; j++) + if ( line->d.info[j].key == info_id ) break; + if ( j==line->n_info ) return -1; + + bcf_info_t *info = &line->d.info[j]; + if ( info->len == 1 ) + { + if ( info->type==BCF_BT_FLOAT ) *((double*)value) = info->v1.f; + else if ( info->type==BCF_BT_INT8 || info->type==BCF_BT_INT16 || info->type==BCF_BT_INT32 ) *((int64_t*)value) = info->v1.i; + return 1; + } + + if ( ivec<0 ) ivec = 0; + + #define BRANCH(type_t, is_missing, is_vector_end, out_type_t) { \ + type_t *p = (type_t *) info->vptr; \ + for (j=0; jlen; j++) \ + { \ + if ( is_vector_end ) return 0; \ + } \ + if ( is_missing ) return 0; \ + *((out_type_t*)value) = p[j]; \ + return 1; \ + } + switch (info->type) { + case BCF_BT_INT8: BRANCH(int8_t, p[j]==bcf_int8_missing, p[j]==bcf_int8_vector_end, int64_t); break; + case BCF_BT_INT16: BRANCH(int16_t, p[j]==bcf_int16_missing, p[j]==bcf_int16_vector_end, int64_t); break; + case BCF_BT_INT32: BRANCH(int32_t, p[j]==bcf_int32_missing, p[j]==bcf_int32_vector_end, int64_t); break; + case BCF_BT_FLOAT: BRANCH(float, bcf_float_is_missing(p[j]), bcf_float_is_vector_end(p[j]), double); break; + default: fprintf(stderr,"todo: type %d\n", info->type); exit(1); break; + } + #undef BRANCH + return -1; // this shouldn't happen +} + +static void filters_set_pos(filter_t *flt, bcf1_t *line, token_t *tok) +{ + tok->values[0] = line->pos+1; + tok->nvalues = 1; +} + +static void filters_set_info_int(filter_t *flt, bcf1_t *line, token_t *tok) +{ + if ( tok->idx==-2 ) + { + int i; + tok->nvalues = bcf_get_info_int32(flt->hdr,line,tok->tag,&flt->tmpi,&flt->mtmpi); + if ( tok->nvalues<=0 ) tok->nvalues = 0; + else + { + hts_expand(double,tok->nvalues,tok->mvalues,tok->values); + for (i=0; invalues; i++) tok->values[i] = flt->tmpi[i]; + } + } + else + { + int64_t value; + if ( bcf_get_info_value(line,tok->hdr_id,tok->idx,&value) <= 0 ) + tok->nvalues = 0; + else + { + tok->values[0] = value; + tok->nvalues = 1; + } + } +} + +static void filters_set_info_float(filter_t *flt, bcf1_t *line, token_t *tok) +{ + if ( tok->idx==-2 ) + { + int i; + tok->nvalues = bcf_get_info_float(flt->hdr,line,tok->tag,&flt->tmpf,&flt->mtmpf); + if ( tok->nvalues<=0 ) tok->nvalues = 0; + else + { + hts_expand(double,tok->nvalues,tok->mvalues,tok->values); + for (i=0; invalues; i++) + if ( bcf_float_is_missing(flt->tmpf[i]) ) bcf_double_set_missing(tok->values[i]); + else tok->values[i] = flt->tmpf[i]; + } + } + else + { + double value; + if ( bcf_get_info_value(line,tok->hdr_id,tok->idx,&value) <= 0 ) + tok->nvalues = 0; + else + { + tok->values[0] = value; + tok->nvalues = 1; + } + } +} + +static void filters_set_info_string(filter_t *flt, bcf1_t *line, token_t *tok) +{ + int m = (int)tok->values[0]; + int n = bcf_get_info_string(flt->hdr,line,tok->tag,&tok->str_value,&m); + if ( n<0 ) { tok->nvalues = 0; return; } + tok->values[0] = m; // allocated length + + if ( tok->idx>=0 ) + { + // get ith field (i=tok->idx) + int i = 0; + char *ss = tok->str_value, *se = tok->str_value + n; + while ( ssidx ) + { + if ( *ss==',' ) i++; + ss++; + } + if ( ss==se || i!=tok->idx ) { tok->nvalues = 0; return; } + se = ss; + while ( se-tok->str_valuestr_value ) *se = 0; + else + { + memmove(tok->str_value,ss,se-ss); + tok->str_value[se-ss] = 0; + } + tok->nvalues = se-ss; + } + else if ( tok->idx==-2 ) tok->nvalues = n; +} + +static void filters_set_info_flag(filter_t *flt, bcf1_t *line, token_t *tok) +{ + int j; + for (j=0; jn_info; j++) + if ( line->d.info[j].key == tok->hdr_id ) break; + tok->values[0] = j==line->n_info ? 0 : 1; + tok->nvalues = 1; +} + +static void filters_set_format_int(filter_t *flt, bcf1_t *line, token_t *tok) +{ + int i; + if ( (tok->nvalues=bcf_get_format_int32(flt->hdr,line,tok->tag,&flt->tmpi,&flt->mtmpi))<0 ) + tok->nvalues = 0; + else + { + int is_missing = 1; + hts_expand(double,tok->nvalues,tok->mvalues,tok->values); + for (i=0; invalues; i++) + { + if ( flt->tmpi[i]==bcf_int32_missing || flt->tmpi[i]==bcf_int32_vector_end ) + bcf_double_set_missing(tok->values[i]); + else + { + tok->values[i] = flt->tmpi[i]; + is_missing = 0; + } + } + if ( is_missing ) tok->nvalues = 0; + else if ( tok->idx >= 0 ) + { + int nsmpl = bcf_hdr_nsamples(flt->hdr); + int nvals = tok->nvalues / nsmpl; + if ( tok->idx >= nvals ) + tok->nvalues = 0; // the index is too big + else + { + for (i=0; ivalues[i] = tok->values[i*nvals+tok->idx]; + tok->nvalues = nsmpl; + } + } + } + tok->nsamples = tok->nvalues; +} +static void filters_set_format_float(filter_t *flt, bcf1_t *line, token_t *tok) +{ + int i; + if ( (tok->nvalues=bcf_get_format_float(flt->hdr,line,tok->tag,&flt->tmpf,&flt->mtmpf))<=0 ) + { + tok->nvalues = tok->nsamples = 0; // missing values + } + else + { + int is_missing = 1; + hts_expand(double,tok->nvalues,tok->mvalues,tok->values); + for (i=0; invalues; i++) + { + if ( bcf_float_is_missing(flt->tmpf[i]) || bcf_float_is_vector_end(flt->tmpf[i]) ) + bcf_double_set_missing(tok->values[i]); + else + { + tok->values[i] = flt->tmpf[i]; + is_missing = 0; + } + } + if ( is_missing ) tok->nvalues = 0; + else if ( tok->idx >= 0 ) + { + int nsmpl = bcf_hdr_nsamples(flt->hdr); + int nvals = tok->nvalues / nsmpl; + if ( tok->idx >= nvals ) + tok->nvalues = 0; // the index is too big + else + { + for (i=0; ivalues[i] = tok->values[i*nvals+tok->idx]; + tok->nvalues = nsmpl; + } + } + } + tok->nsamples = tok->nvalues; +} +static void filters_set_format_string(filter_t *flt, bcf1_t *line, token_t *tok) +{ + int ndim = tok->nsamples * (int)tok->values[0]; + int ret = bcf_get_format_char(flt->hdr,line,tok->tag,&tok->str_value,&ndim); + + int nsmpl = bcf_hdr_nsamples(flt->hdr); + ndim /= nsmpl; + tok->values[0] = ndim; + + if ( ret<=0 ) + { + tok->nvalues = 0; + return; + } + + if ( tok->idx < 0 ) // scalar + { + tok->nvalues = tok->nsamples = nsmpl; + return; + } + + // vector + int i; + for (i=0; istr_value + i*ndim; + int is = 0, ivec = 0; + while ( ivecidx && isidx || is==ndim || !ss[is] ) + { + ss[0] = '.'; + ss[1] = 0; + continue; + } + int ie = is; + while ( ienvalues = 0; + return; + } + tok->nvalues = ret; + tok->nsamples = nsmpl; +} +static void filters_set_genotype_string(filter_t *flt, bcf1_t *line, token_t *tok) +{ + bcf_fmt_t *fmt = bcf_get_fmt(flt->hdr, line, "GT"); + if ( !fmt ) + { + tok->nvalues = tok->nsamples = 0; + return; + } + int i, blen = 4, nsmpl = bcf_hdr_nsamples(flt->hdr); + kstring_t str; + +gt_length_too_big: + str.s = tok->str_value; str.m = tok->values[0] * nsmpl; str.l = 0; + for (i=0; i blen ) + { + // too many alternate alleles or ploidy is too large, the genotype does not fit + // three characters ("0/0" vs "10/10"). + tok->str_value = str.s; + blen *= 2; + goto gt_length_too_big; + } + + plen = str.l - plen; + while ( plennvalues = str.l; + tok->nsamples = nsmpl; + tok->values[0] = blen; + tok->str_value = str.s; +} +static void filters_set_ref_string(filter_t *flt, bcf1_t *line, token_t *tok) +{ + kstring_t str; str.s = tok->str_value; str.m = tok->values[0]; str.l = 0; + kputs(line->d.allele[0], &str); + tok->nvalues = str.l; + tok->values[0] = str.m; + tok->str_value = str.s; +} +static void filters_set_alt_string(filter_t *flt, bcf1_t *line, token_t *tok) +{ + kstring_t str; str.s = tok->str_value; str.m = tok->values[0]; str.l = 0; + if ( tok->idx>=0 ) + { + if ( line->n_allele >= tok->idx ) + kputs(line->d.allele[tok->idx], &str); + else + kputc('.', &str); + } + else if ( line->n_allele>1 ) + { + kputs(line->d.allele[1], &str); + int i; + for (i=2; in_allele; i++) + { + kputc(',', &str); + kputs(line->d.allele[i], &str); + } + } + else if ( line->n_allele==1 ) + kputc('.', &str); + tok->nvalues = str.l; + tok->values[0] = str.m; + tok->str_value = str.s; +} +static void filters_set_nalt(filter_t *flt, bcf1_t *line, token_t *tok) +{ + tok->nvalues = 1; + tok->values[0] = line->n_allele - 1; +} +static void filters_set_ac(filter_t *flt, bcf1_t *line, token_t *tok) +{ + hts_expand(int32_t, line->n_allele, flt->mtmpi, flt->tmpi); + if ( !bcf_calc_ac(flt->hdr, line, flt->tmpi, BCF_UN_INFO|BCF_UN_FMT) ) + { + tok->nvalues = 0; + return; + } + int i, an = flt->tmpi[0]; + for (i=1; in_allele; i++) an += flt->tmpi[i]; + if ( !an ) + { + tok->nvalues = 0; + return; + } + flt->tmpi[0] = an; // for filters_set_[mac|af|maf] + if ( tok->idx>=0 ) + { + tok->nvalues = 1; + tok->values[0] = tok->idx+1n_allele ? flt->tmpi[tok->idx+1] : 0; + } + else if ( line->n_allele==1 ) // no ALT + { + tok->nvalues = 1; + tok->values[0] = 0; + } + else + { + hts_expand(double,line->n_allele,tok->mvalues,tok->values); + for (i=1; in_allele; i++) + tok->values[i-1] = flt->tmpi[i]; + tok->nvalues = line->n_allele - 1; + } +} +static void filters_set_an(filter_t *flt, bcf1_t *line, token_t *tok) +{ + filters_set_ac(flt,line,tok); + tok->values[0] = tok->nvalues ? flt->tmpi[0] : 0; + tok->nvalues = 1; +} +static void filters_set_mac(filter_t *flt, bcf1_t *line, token_t *tok) +{ + filters_set_ac(flt,line,tok); + if ( !tok->nvalues ) return; + int i, an = flt->tmpi[0]; + for (i=0; invalues; i++) + if ( tok->values[i] > an*0.5 ) tok->values[i] = an - tok->values[i]; +} +static void filters_set_af(filter_t *flt, bcf1_t *line, token_t *tok) +{ + filters_set_ac(flt,line,tok); + if ( !tok->nvalues ) return; + int i, an = flt->tmpi[0]; + for (i=0; invalues; i++) + tok->values[i] /= (double)an; +} +static void filters_set_maf(filter_t *flt, bcf1_t *line, token_t *tok) +{ + filters_set_ac(flt,line,tok); + if ( !tok->nvalues ) return; + int i, an = flt->tmpi[0]; + for (i=0; invalues; i++) + { + tok->values[i] /= (double)an; + if ( tok->values[i] > 0.5 ) tok->values[i] = 1 - tok->values[i]; + } +} + +static void set_max(filter_t *flt, bcf1_t *line, token_t *tok) +{ + double val = -HUGE_VAL; + int i; + for (i=0; invalues; i++) + { + if ( !bcf_double_is_missing(tok->values[i]) && val < tok->values[i] ) val = tok->values[i]; + } + tok->values[0] = val; + tok->nvalues = 1; + tok->nsamples = 0; +} +static void set_min(filter_t *flt, bcf1_t *line, token_t *tok) +{ + double val = HUGE_VAL; + int i; + for (i=0; invalues; i++) + if ( !bcf_double_is_missing(tok->values[i]) && val > tok->values[i] ) val = tok->values[i]; + tok->values[0] = val; + tok->nvalues = 1; + tok->nsamples = 0; +} +static void set_avg(filter_t *flt, bcf1_t *line, token_t *tok) +{ + double val = 0; + int i, n = 0; + for (i=0; invalues; i++) + if ( !bcf_double_is_missing(tok->values[i]) ) { val += tok->values[i]; n++; } + tok->values[0] = n ? val / n : 0; + tok->nvalues = 1; + tok->nsamples = 0; +} +static void set_sum(filter_t *flt, bcf1_t *line, token_t *tok) +{ + double val = 0; + int i, n = 0; + for (i=0; invalues; i++) + if ( !bcf_double_is_missing(tok->values[i]) ) { val += tok->values[i]; n++; } + tok->values[0] = val; + tok->nvalues = 1; + tok->nsamples = 0; +} +static void set_abs(filter_t *flt, bcf1_t *line, token_t *tok) +{ + if ( tok->is_str ) error("ABS() can be applied only on numeric values\n"); + int i; + for (i=0; invalues; i++) + tok->values[i] = fabs(tok->values[i]); +} +static void set_strlen(filter_t *flt, bcf1_t *line, token_t *tok) +{ + tok->is_str = 0; + if ( !tok->nvalues ) return; + if ( tok->idx==-2 ) + { + int i = 0; + char *ss = tok->str_value; + while ( *ss ) + { + char *se = ss; + while ( *se && *se!=',' ) se++; + if ( !*se ) tok->values[i] = strlen(ss); + else + { + *se = 0; + tok->values[i] = strlen(ss); + *se = ','; + } + ss = *se ? se + 1 : se; + i++; + } + tok->nvalues = i; + } + else + { + tok->values[0] = strlen(tok->str_value); + tok->nvalues = 1; + } +} +#define VECTOR_ARITHMETICS(atok,btok,AOP) \ +{ \ + int i, has_values = 0; \ + if ( !(atok)->nvalues || !(btok)->nvalues ) /* missing values */ \ + { \ + (atok)->nvalues = 0; (atok)->nsamples = 0; \ + } \ + else \ + { \ + if ( ((atok)->nsamples && (btok)->nsamples) || (!(atok)->nsamples && !(btok)->nsamples)) \ + { \ + for (i=0; i<(atok)->nvalues; i++) \ + { \ + if ( bcf_double_is_missing((atok)->values[i]) ) continue; \ + if ( bcf_double_is_missing((btok)->values[i]) ) { bcf_double_set_missing((atok)->values[i]); continue; } \ + has_values = 1; \ + (atok)->values[i] = (atok)->values[i] AOP (btok)->values[i]; \ + } \ + } \ + else if ( (btok)->nsamples ) \ + { \ + hts_expand(double,(btok)->nvalues,(atok)->mvalues,(atok)->values); \ + for (i=0; i<(btok)->nvalues; i++) \ + { \ + if ( bcf_double_is_missing((atok)->values[0]) || bcf_double_is_missing((btok)->values[i]) ) \ + { \ + bcf_double_set_missing((atok)->values[i]); \ + continue; \ + } \ + has_values = 1; \ + (atok)->values[i] = (atok)->values[0] AOP (btok)->values[i]; \ + } \ + (atok)->nvalues = (btok)->nvalues; \ + (atok)->nsamples = (btok)->nsamples; \ + } \ + else if ( (atok)->nsamples ) \ + { \ + for (i=0; i<(atok)->nvalues; i++) \ + { \ + if ( bcf_double_is_missing((atok)->values[i]) || bcf_double_is_missing((btok)->values[0]) ) \ + { \ + bcf_double_set_missing((atok)->values[i]); \ + continue; \ + } \ + has_values = 1; \ + (atok)->values[i] = (atok)->values[i] AOP (btok)->values[0]; \ + } \ + } \ + } \ + if ( !has_values ) { (atok)->nvalues = 0; (atok)->nsamples = 0; } \ +} + +static int vector_logic_and(token_t *atok, token_t *btok, int and_type) +{ + // We are comparing either two scalars (result of INFO tag vs a threshold), two vectors (two FORMAT fields), + // or a vector and a scalar (FORMAT field vs threshold) + int i, pass_site = 0; + if ( !atok->nvalues || !btok->nvalues ) + { + atok->nvalues = atok->nsamples = 0; + return 0; + } + if ( !atok->nsamples && !btok->nsamples ) return atok->pass_site && btok->pass_site; + if ( atok->nsamples && btok->nsamples ) + { + if ( and_type==TOK_AND ) + { + // perform AND within a sample + for (i=0; insamples; i++) + { + atok->pass_samples[i] = atok->pass_samples[i] && btok->pass_samples[i]; + if ( !pass_site && atok->pass_samples[i] ) pass_site = 1; + } + } + else + { + // perform AND across samples + int pass_a = 0, pass_b = 0; + for (i=0; insamples; i++) + { + if ( atok->pass_samples[i] ) pass_a = 1; + atok->pass_samples[i] = atok->pass_samples[i] && btok->pass_samples[i]; + } + for (i=0; insamples; i++) + { + if ( btok->pass_samples[i] ) { pass_b = 1; break; } + } + pass_site = pass_a && pass_b; + } + return pass_site; + } + if ( btok->nsamples ) + { + for (i=0; insamples; i++) + { + atok->pass_samples[i] = atok->pass_site && btok->pass_samples[i]; + if ( !pass_site && atok->pass_samples[i] ) pass_site = 1; + } + atok->nsamples = btok->nsamples; + return pass_site; + } + /* atok->nsamples!=0 */ + for (i=0; insamples; i++) + { + atok->pass_samples[i] = atok->pass_samples[i] && btok->pass_site; + if ( !pass_site && atok->pass_samples[i] ) pass_site = 1; + } + return pass_site; +} +static int vector_logic_or(token_t *atok, token_t *btok, int or_type) +{ + int i, pass_site = 0; + if ( !atok->nvalues && !btok->nvalues ) // missing sites in both + { + atok->nvalues = atok->nsamples = 0; + return 0; + } + if ( !atok->nvalues ) // missing value in a + { + for (i=0; insamples; i++) + atok->pass_samples[i] = btok->pass_samples[i]; + atok->nsamples = btok->nsamples; + atok->nvalues = 1; + return btok->pass_site; + } + if ( !btok->nvalues ) // missing value in b + { + btok->nvalues = 1; + return atok->pass_site; + } + + if ( !atok->nsamples && !btok->nsamples ) return atok->pass_site || btok->pass_site; + if ( !atok->nsamples ) + { + if ( or_type==TOK_OR ) + { + for (i=0; insamples; i++) + { + atok->pass_samples[i] = btok->pass_samples[i]; + if ( atok->pass_site || atok->pass_samples[i] ) pass_site = 1; + } + } + else + { + for (i=0; insamples; i++) + { + atok->pass_samples[i] = atok->pass_site || btok->pass_samples[i]; + if ( atok->pass_samples[i] ) pass_site = 1; + } + } + atok->nsamples = btok->nsamples; + return pass_site; + } + if ( !btok->nsamples ) // vector vs site + { + if ( or_type==TOK_OR ) + { + for (i=0; insamples; i++) + if ( btok->pass_site || atok->pass_samples[i] ) pass_site = 1; + } + else + { + for (i=0; insamples; i++) + { + atok->pass_samples[i] = atok->pass_samples[i] || btok->pass_site; + if ( atok->pass_samples[i] ) pass_site = 1; + } + } + return pass_site; + } + for (i=0; insamples; i++) + { + atok->pass_samples[i] = atok->pass_samples[i] || btok->pass_samples[i]; + if ( !pass_site && atok->pass_samples[i] ) pass_site = 1; + } + return pass_site; +} + +#define CMP_MISSING(atok,btok,CMP_OP,ret) \ +{ \ + if ( (atok)->nsamples || (btok)->nsamples ) error("todo: Querying of missing values in FORMAT\n"); \ + token_t *tok = (atok)->is_missing ? (btok) : (atok); \ + (ret) = ( tok->nvalues CMP_OP 1 ) ? 0 : 1; \ + tok->nvalues = 1; \ +} + +#define CMP_VECTORS(atok,btok,CMP_OP,ret) \ +{ \ + int i, j, has_values = 0, pass_site = 0; \ + if ( !(atok)->nvalues || !(btok)->nvalues ) { (atok)->nvalues = 0; (atok)->nsamples = 0; (ret) = 0; } \ + else \ + { \ + if ( (atok)->nsamples && (btok)->nsamples ) \ + { \ + for (i=0; i<(atok)->nsamples; i++) \ + { \ + has_values = 1; \ + if ( (atok)->values[i] CMP_OP (btok)->values[i] ) { (atok)->pass_samples[i] = 1; pass_site = 1; } \ + else (atok)->pass_samples[i] = 0; \ + } \ + if ( !has_values ) (atok)->nvalues = 0; \ + } \ + else if ( (atok)->nsamples ) \ + { \ + for (i=0; i<(atok)->nsamples; i++) \ + { \ + /*if ( bcf_double_is_missing((atok)->values[i]) ) { (atok)->pass_samples[i] = 0; continue; }*/ \ + has_values = 1; \ + if ( (atok)->values[i] CMP_OP (btok)->values[0] ) { (atok)->pass_samples[i] = 1; pass_site = 1; } \ + else (atok)->pass_samples[i] = 0; \ + } \ + if ( !has_values ) (atok)->nvalues = 0; \ + } \ + else if ( (btok)->nsamples ) \ + { \ + for (i=0; i<(btok)->nsamples; i++) \ + { \ + if ( bcf_double_is_missing((btok)->values[i]) ) { (atok)->pass_samples[i] = 0; continue; } \ + has_values = 1; \ + if ( (atok)->values[0] CMP_OP (btok)->values[i] ) { (atok)->pass_samples[i] = 1; pass_site = 1; } \ + else (atok)->pass_samples[i] = 0; \ + } \ + (atok)->nvalues = (btok)->nvalues; \ + (atok)->nsamples = (btok)->nsamples; \ + if ( !has_values ) (atok)->nvalues = 0; \ + } \ + else if ( (atok)->idx==-2 || (btok)->idx==-2 ) \ + { \ + /* any field can match: [*] */ \ + for (i=0; i<(atok)->nvalues; i++) \ + { \ + for (j=0; j<(btok)->nvalues; j++) \ + if ( (atok)->values[i] CMP_OP (btok)->values[j] ) { pass_site = 1; i = (atok)->nvalues; break; } \ + } \ + } \ + else \ + { \ + if ( (atok)->values[0] CMP_OP (btok)->values[0] ) { pass_site = 1; } \ + } \ + /*fprintf(stderr,"pass=%d\n", pass_site);*/ \ + (ret) = pass_site; \ + } \ +} +static int cmp_vector_strings(token_t *atok, token_t *btok, int logic) // logic: TOK_EQ or TOK_NE +{ + if ( !atok->nvalues ) { return 0; } + if ( !btok->nvalues ) { atok->nvalues = 0; return 0; } + int i, pass_site = 0; + if ( atok->nsamples && atok->nsamples==btok->nsamples ) + { + for (i=0; insamples; i++) + { + char *astr = atok->str_value + i*(int)atok->values[0]; + char *bstr = btok->str_value + i*(int)btok->values[0]; + char *aend = astr + (int)atok->values[0], *a = astr; + while ( avalues[0], *b = bstr; + while ( bpass_samples[i] = 0; + else atok->pass_samples[i] = strncmp(astr,bstr,a-astr)==0 ? 1 : 0; + if ( logic!=TOK_EQ ) + atok->pass_samples[i] = atok->pass_samples[i] ? 0 : 1; + pass_site |= atok->pass_samples[i]; + } + if ( !atok->nsamples ) atok->nsamples = btok->nsamples; + } + else if ( !atok->nsamples && !btok->nsamples ) + { + if ( atok->idx==-2 || btok->idx==-2 ) + { + // any field can match: [*] + if ( atok->idx==-2 && btok->idx==-2 ) + error("fixme: Expected at least one scalar value [%s %s %s]\n", atok->tag ? atok->tag : btok->tag, atok->str_value,btok->str_value); + token_t *xtok, *ytok; // xtok is scalar, ytok array + if ( btok->idx==-2 ) { xtok = atok; ytok = btok; } + else { xtok = btok; ytok = atok; } + char *xstr = xtok->str_value, *xend = xstr + xtok->nvalues; + char *ystr = ytok->str_value, *yend = ystr + ytok->nvalues, *y = ystr; + while ( y<=yend ) + { + if ( y==yend || *y==',' ) + { + if ( y-ystr==xend-xstr && !strncmp(xstr,ystr,xend-xstr) ) + { + pass_site = 1; + break; + } + ystr = y+1; + } + y++; + } + } + else + pass_site = strcmp(atok->str_value,btok->str_value) ? 0 : 1; + if ( logic!=TOK_EQ ) pass_site = pass_site ? 0 : 1; + } + else + { + token_t *xtok, *ytok; + if ( !atok->nsamples ) { xtok = atok; ytok = btok; } + else { xtok = btok; ytok = atok; } + char *xstr = xtok->str_value; + char *xend = xstr + (int)xtok->values[0], *x = xstr; + while ( xnsamples; i++) + { + char *ystr = ytok->str_value + i*(int)ytok->values[0]; + char *yend = ystr + (int)ytok->values[0], *y = ystr; + while ( ypass_samples[i] = 0; + else atok->pass_samples[i] = strncmp(xstr,ystr,x-xstr)==0 ? 1 : 0; + if ( logic!=TOK_EQ ) + atok->pass_samples[i] = atok->pass_samples[i] ? 0 : 1; + pass_site |= atok->pass_samples[i]; + } + if ( !atok->nsamples ) + atok->nvalues = atok->nsamples = btok->nsamples; // is it a bug? not sure if atok->nvalues should be set + } + return pass_site; +} +static int regex_vector_strings(token_t *atok, token_t *btok, int negate) +{ + int i, pass_site = 0; + if ( atok->nsamples ) + { + for (i=0; insamples; i++) + { + char *ptr = atok->str_value + i*(int)atok->values[0]; + atok->pass_samples[i] = regexec(btok->regex, ptr, 0,NULL,0) ? 0 : 1; + if ( negate ) atok->pass_samples[i] = atok->pass_samples[i] ? 0 : 1; + pass_site |= atok->pass_samples[i]; + } + return pass_site; + } + pass_site = regexec(btok->regex, atok->str_value, 0,NULL,0) ? 0 : 1; + if ( negate ) pass_site = pass_site ? 0 : 1; + return pass_site; +} + +static int filters_init1(filter_t *filter, char *str, int len, token_t *tok) +{ + tok->tok_type = TOK_VAL; + tok->hdr_id = -1; + tok->pass_site = -1; + tok->idx = -1; + + // is this a string constant? + if ( str[0]=='"' || str[0]=='\'' ) + { + int quote = str[0]; + if ( str[len-1] != quote ) error("TODO: [%s]\n", filter->str); + tok->key = (char*) calloc(len-1,sizeof(char)); + hts_expand(double,1,tok->mvalues,tok->values); + tok->values[0] = len-2; + memcpy(tok->key,str+1,len-2); + tok->key[len-2] = 0; + tok->is_str = 1; + tok->nvalues = len-2; + if ( !strcmp(".",tok->key) ) tok->is_missing = 1; + return 0; + } + + // is it a file? + if ( str[0]=='@' ) + { + tok->tag = (char*) calloc(len+1,sizeof(char)); + memcpy(tok->tag,str,len); + tok->tag[len] = 0; + wordexp_t wexp; + wordexp(tok->tag+1, &wexp, 0); + if ( !wexp.we_wordc ) error("No such file: %s\n", tok->tag+1); + int i, n; + char **list = hts_readlist(wexp.we_wordv[0], 1, &n); + if ( !list ) error("Could not read: %s\n", wexp.we_wordv[0]); + wordfree(&wexp); + tok->hash = khash_str2int_init(); + for (i=0; ihash,list[i]) ) + khash_str2int_inc(tok->hash,list[i]); + else + free(list[i]); + } + free(list); + return 0; + } + + int is_fmt = -1; + if ( !strncasecmp(str,"FMT/",4) ) { str += 4; len -= 4; is_fmt = 1; } + else if ( !strncasecmp(str,"FORMAT/",7) ) { str += 7; len -= 7; is_fmt = 1; } + else + { + if ( !strncasecmp(str,"INFO/",5) ) { is_fmt = 0; str += 5; len -= 5; } + else if ( !strncasecmp(str,"QUAL",len) || !strncmp(str,"%QUAL",len) /* for backward compatibility */ ) + { + tok->setter = filters_set_qual; + tok->tag = strdup("QUAL"); + return 0; + } + else if ( !strncasecmp(str,"TYPE",len) || !strncmp(str,"%TYPE",len) /* for backward compatibility */ ) + { + tok->setter = filters_set_type; + tok->tag = strdup("TYPE"); + return 0; + } + else if ( !strncasecmp(str,"FILTER",len) || !strncmp(str,"%FILTER",len) /* for backward compatibility */ ) + { + tok->comparator = filters_cmp_filter; + tok->tag = strdup("FILTER"); + filter->max_unpack |= BCF_UN_FLT; + return 0; + } + else if ( !strncasecmp(str,"ID",len) || !strncasecmp(str,"%ID",len) /* for backward compatibility */ ) + { + tok->comparator = filters_cmp_id; + tok->tag = strdup("ID"); + return 0; + } + else if ( !strncasecmp(str,"POS",len) ) + { + tok->setter = &filters_set_pos; + tok->tag = strdup("POS"); + return 0; + } + else if ( !strncasecmp(str,"REF",len) ) + { + tok->setter = &filters_set_ref_string; + tok->is_str = 1; + tok->tag = strdup("REF"); + return 0; + } + else if ( !strncasecmp(str,"ALT",len) ) + { + tok->setter = &filters_set_alt_string; + tok->is_str = 1; + tok->tag = strdup("ALT"); + return 0; + } + else if ( !strncasecmp(str,"N_ALT",len) ) + { + tok->setter = &filters_set_nalt; + tok->tag = strdup("N_ALT"); + return 0; + } + else if ( !strncasecmp(str,"N_SAMPLES",len) ) + { + tok->tok_type = TOK_VAL; + tok->threshold = bcf_hdr_nsamples(filter->hdr); + return 0; + } + } + + // does it have array subscript? + int is_array = 0; + kstring_t tmp = {0,0,0}; + kputsn(str, len, &tmp); + if ( tmp.s[tmp.l-1] == ']' ) + { + int i; + for (i=0; iidx = -2; // tag[*] .. any field + else + { + char *end; + tok->idx = strtol(tmp.s+is_array, &end, 10); + if ( *end!=']' ) error("Could not parse the index: %s[%s\n", tmp.s,tmp.s+is_array); + } + } + } + tok->hdr_id = bcf_hdr_id2int(filter->hdr,BCF_DT_ID,tmp.s); + if ( is_fmt==-1 ) + { + if ( tok->hdr_id >=0 ) + { + if ( bcf_hdr_idinfo_exists(filter->hdr,BCF_HL_INFO,tok->hdr_id) ) is_fmt = 0; + else if ( bcf_hdr_idinfo_exists(filter->hdr,BCF_HL_FMT,tok->hdr_id) ) is_fmt = 1; + } + if ( is_fmt==-1 ) is_fmt = 0; + } + tok->type = is_fmt ? BCF_HL_FMT : BCF_HL_INFO; + if ( is_fmt ) filter->max_unpack |= BCF_UN_FMT; + if ( tok->hdr_id>=0 ) + { + if ( is_fmt && !strcmp("GT",tmp.s) ) + { + tok->setter = &filters_set_genotype_string; tok->is_str = 1; + } + else if ( is_fmt ) + { + if ( !bcf_hdr_idinfo_exists(filter->hdr,BCF_HL_FMT,tok->hdr_id) ) + error("No such FORMAT field: %s\n", tmp.s); + if ( bcf_hdr_id2number(filter->hdr,BCF_HL_FMT,tok->hdr_id)!=1 && !is_array ) + error("Error: FORMAT vectors must be subscripted, e.g. %s[0] or %s[*]\n", tmp.s, tmp.s); + switch ( bcf_hdr_id2type(filter->hdr,BCF_HL_FMT,tok->hdr_id) ) + { + case BCF_HT_INT: tok->setter = &filters_set_format_int; break; + case BCF_HT_REAL: tok->setter = &filters_set_format_float; break; + case BCF_HT_STR: tok->setter = &filters_set_format_string; tok->is_str = 1; break; + default: error("[%s:%d %s] FIXME\n", __FILE__,__LINE__,__FUNCTION__); + } + } + else if ( !bcf_hdr_idinfo_exists(filter->hdr,BCF_HL_INFO,tok->hdr_id) ) + error("No such INFO field: %s\n", tmp.s); + else + { + if ( bcf_hdr_id2type(filter->hdr,BCF_HL_INFO,tok->hdr_id) == BCF_HT_FLAG ) + tok->setter = filters_set_info_flag; + else + { + if ( bcf_hdr_id2type(filter->hdr,BCF_HL_INFO,tok->hdr_id) == BCF_HT_STR ) tok->is_str = 1; + if ( bcf_hdr_id2number(filter->hdr,BCF_HL_INFO,tok->hdr_id)==1 ) + tok->setter = filters_set_info; + else + { + switch ( bcf_hdr_id2type(filter->hdr,BCF_HL_INFO,tok->hdr_id) ) + { + case BCF_HT_INT: tok->setter = &filters_set_info_int; break; + case BCF_HT_REAL: tok->setter = &filters_set_info_float; break; + case BCF_HT_STR: tok->setter = &filters_set_info_string; tok->is_str = 1; break; + default: error("[%s:%d %s] FIXME\n", __FILE__,__LINE__,__FUNCTION__); + } + if(!is_array) tok->idx = -2; + } + } + filter->max_unpack |= BCF_UN_INFO; + } + tok->tag = strdup(tmp.s); + if ( tmp.s ) free(tmp.s); + return 0; + } + else if ( !strcasecmp(tmp.s,"ALT") ) + { + tok->setter = &filters_set_alt_string; + tok->is_str = 1; + tok->tag = strdup(tmp.s); + free(tmp.s); + return 0; + } + else if ( !strcasecmp(tmp.s,"AN") ) + { + tok->setter = &filters_set_an; + tok->tag = strdup("AN"); + free(tmp.s); + return 0; + } + else if ( !strcasecmp(tmp.s,"AC") ) + { + tok->setter = &filters_set_ac; + tok->tag = strdup("AC"); + free(tmp.s); + return 0; + } + else if ( !strcasecmp(tmp.s,"MAC") ) + { + tok->setter = &filters_set_mac; + tok->tag = strdup("MAC"); + free(tmp.s); + return 0; + } + else if ( !strcasecmp(tmp.s,"AF") ) + { + tok->setter = &filters_set_af; + tok->tag = strdup("AF"); + free(tmp.s); + return 0; + } + else if ( !strcasecmp(tmp.s,"MAF") ) + { + tok->setter = &filters_set_maf; + tok->tag = strdup("MAF"); + free(tmp.s); + return 0; + } + + // is it a value? Here we parse as integer/float separately and use strtof + // rather than strtod, because the more accurate double representation + // would invalidate floating point comparisons like QUAL=59.2, obtained via + // htslib/vcf parser + char *end; + tok->threshold = strtol(tmp.s, &end, 10); // integer? + if ( end - tmp.s != strlen(tmp.s) ) + { + errno = 0; + tok->threshold = strtof(tmp.s, &end); // float? + if ( errno!=0 || end!=tmp.s+len ) error("[%s:%d %s] Error: the tag \"INFO/%s\" is not defined in the VCF header\n", __FILE__,__LINE__,__FUNCTION__,tmp.s); + } + + if ( tmp.s ) free(tmp.s); + return 0; +} + + +static void filter_debug_print(token_t *toks, token_t **tok_ptrs, int ntoks) +{ + int i; + for (i=0; itok_type==TOK_VAL ) + { + if ( tok->key ) + fprintf(stderr,"%s", tok->key); + else if ( tok->tag ) + fprintf(stderr,"%s", tok->tag); + else + fprintf(stderr,"%e", tok->threshold); + } + else + fprintf(stderr,"%c", TOKEN_STRING[tok->tok_type]); + if ( tok->setter ) fprintf(stderr,"\t[setter %p]", tok->setter); + fprintf(stderr,"\n"); + } +} + + +// Parse filter expression and convert to reverse polish notation. Dijkstra's shunting-yard algorithm +filter_t *filter_init(bcf_hdr_t *hdr, const char *str) +{ + filter_t *filter = (filter_t *) calloc(1,sizeof(filter_t)); + filter->str = strdup(str); + filter->hdr = hdr; + filter->max_unpack |= BCF_UN_STR; + + int nops = 0, mops = 0, *ops = NULL; // operators stack + int nout = 0, mout = 0; // filter tokens, RPN + token_t *out = NULL; + char *tmp = filter->str; + int last_op = -1; + while ( *tmp ) + { + int len, ret; + ret = filters_next_token(&tmp, &len); + if ( ret==-1 ) error("Missing quotes in: %s\n", str); + + //fprintf(stderr,"token=[%c] .. [%s] %d\n", TOKEN_STRING[ret], tmp, len); + //int i; for (i=0; i0 && ops[nops-1]!=TOK_LFT ) + { + nout++; + hts_expand0(token_t, nout, mout, out); + out[nout-1].tok_type = ops[nops-1]; + nops--; + } + if ( nops<=0 ) error("Could not parse: %s\n", str); + nops--; + } + else if ( ret!=TOK_VAL ) // one of the operators + { + // detect unary minus: replace -value with -1*(value) + if ( ret==TOK_SUB && last_op!=TOK_VAL && last_op!=TOK_RGT ) + { + nout++; + hts_expand0(token_t, nout, mout, out); + token_t *tok = &out[nout-1]; + tok->tok_type = TOK_VAL; + tok->hdr_id = -1; + tok->pass_site = -1; + tok->threshold = -1.0; + ret = TOK_MULT; + } + else + { + while ( nops>0 && op_prec[ret] < op_prec[ops[nops-1]] ) + { + nout++; + hts_expand0(token_t, nout, mout, out); + out[nout-1].tok_type = ops[nops-1]; + nops--; + } + } + nops++; + hts_expand(int, nops, mops, ops); + ops[nops-1] = ret; + } + else if ( !len ) + { + if ( *tmp && !isspace(*tmp) ) error("Could not parse the expression: [%s]\n", str); + break; // all tokens read + } + else // annotation name or filtering value + { + nout++; + hts_expand0(token_t, nout, mout, out); + filters_init1(filter, tmp, len, &out[nout-1]); + tmp += len; + } + last_op = ret; + } + while ( nops>0 ) + { + if ( ops[nops-1]==TOK_LFT || ops[nops-1]==TOK_RGT ) error("Could not parse the expression: [%s]\n", filter->str); + nout++; + hts_expand0(token_t, nout, mout, out); + out[nout-1].tok_type = ops[nops-1]; + nops--; + } + + // In the special cases of TYPE and FILTER the BCF header IDs are yet unknown. Walk through the + // list of operators and convert the strings (e.g. "PASS") to BCF ids. The string value token must be + // just before or after the FILTER token and they must be followed with a comparison operator. + // At this point we also initialize regex expressions which, in RPN, must preceed the LIKE/NLIKE operator. + // Additionally, treat "." as missing value rather than a string in numeric equalities. + // This code is fragile: improve me. + int i; + for (i=0; i0 && out[j].is_str && out[j].key && !strcmp(".",out[j].key) ) + { + int type = bcf_hdr_id2type(filter->hdr,out[k].type,out[k].hdr_id); + if ( type==BCF_HT_INT ) { out[j].is_str = 0; out[j].is_missing = 1; bcf_double_set_missing(out[j].values[0]); } + if ( type==BCF_HT_REAL ) { out[j].is_str = 0; out[j].is_missing = 1; bcf_double_set_missing(out[j].values[0]); } + } + } + if ( out[i].tok_type==TOK_LIKE || out[i].tok_type==TOK_NLIKE ) + { + int j = i-1; + if ( !out[j].key ) + error("Could not parse the expression, wrong value for regex operator: %s\n", filter->str); + out[j].regex = (regex_t *) malloc(sizeof(regex_t)); + int cflags = REG_NOSUB; + int len = strlen(out[j].key); + if ( len>2 && out[j].key[len-1]=='i' && out[j].key[len-2]=='/' && out[j].key[len-3]!='\\' ) + { + out[j].key[len-2] = 0; + cflags |= REG_ICASE; + } + if ( regcomp(out[j].regex, out[j].key, cflags) ) + error("Could not compile the regex expression \"%s\": %s\n", out[j].key,filter->str); + } + if ( out[i].tok_type!=TOK_VAL ) continue; + if ( !out[i].tag ) continue; + if ( !strcmp(out[i].tag,"TYPE") ) + { + if ( i+1==nout ) error("Could not parse the expression: %s\n", filter->str); + int itok, ival; + if ( out[i+1].tok_type==TOK_EQ || out[i+1].tok_type==TOK_NE ) ival = i - 1, itok = i + 1; + else if ( out[i+1].tok_type==TOK_LIKE || out[i+1].tok_type==TOK_NLIKE ) ival = i - 1, itok = i + 1; + else if ( out[i+2].tok_type==TOK_EQ || out[i+2].tok_type==TOK_NE ) itok = i + 2, ival = i + 1; + else if ( out[i+2].tok_type==TOK_LIKE || out[i+2].tok_type==TOK_NLIKE ) itok = i + 2, ival = i + 1; + else error("[%s:%d %s] Could not parse the expression: %s\n", __FILE__,__LINE__,__FUNCTION__, filter->str); + if ( !strcasecmp(out[ival].key,"snp") || !strcasecmp(out[ival].key,"snps") ) { out[ival].threshold = VCF_SNP<<1; out[ival].is_str = 0; } + else if ( !strcasecmp(out[ival].key,"indel") || !strcasecmp(out[ival].key,"indels") ) { out[ival].threshold = VCF_INDEL<<1; out[ival].is_str = 0; } + else if ( !strcasecmp(out[ival].key,"mnp") || !strcasecmp(out[ival].key,"mnps") ) { out[ival].threshold = VCF_MNP<<1; out[ival].is_str = 0; } + else if ( !strcasecmp(out[ival].key,"other") ) { out[ival].threshold = VCF_OTHER<<1; out[ival].is_str = 0; } + else if ( !strcasecmp(out[ival].key,"bnd") ) { out[ival].threshold = VCF_BND<<1; out[ival].is_str = 0; } + else if ( !strcasecmp(out[ival].key,"ref") ) { out[ival].threshold = 1; out[ival].is_str = 0; } + else error("The type \"%s\" not recognised: %s\n", out[ival].key, filter->str); + if ( out[itok].tok_type==TOK_LIKE || out[itok].tok_type==TOK_NLIKE ) out[itok].comparator = filters_cmp_bit_and; + out[ival].tag = out[ival].key; out[ival].key = NULL; + i = itok; + continue; + } + if ( !strcmp(out[i].tag,"FILTER") ) + { + if ( i+1==nout ) error("Could not parse the expression: %s\n", filter->str); + int itok = i, ival; + if ( out[i+1].tok_type==TOK_EQ || out[i+1].tok_type==TOK_NE ) ival = i - 1; + else if ( out[i+1].tok_type==TOK_LIKE ) out[i+1].tok_type = TOK_EQ, ival = i - 1; + else if ( out[i+1].tok_type==TOK_NLIKE ) out[i+1].tok_type = TOK_NE, ival = i - 1; + else if ( out[i+2].tok_type==TOK_EQ || out[i+2].tok_type==TOK_NE ) ival = ++i; + else if ( out[i+2].tok_type==TOK_LIKE ) out[i+2].tok_type = TOK_EQ, ival = ++i; + else if ( out[i+2].tok_type==TOK_NLIKE ) out[i+2].tok_type = TOK_NE, ival = ++i; + else error("[%s:%d %s] Could not parse the expression: %s\n", __FILE__,__LINE__,__FUNCTION__, filter->str); + if ( out[ival].tok_type!=TOK_VAL || !out[ival].key ) + error("[%s:%d %s] Could not parse the expression, an unquoted string value perhaps? %s\n", __FILE__,__LINE__,__FUNCTION__, filter->str); + if ( strcmp(".",out[ival].key) ) + { + out[ival].hdr_id = bcf_hdr_id2int(filter->hdr, BCF_DT_ID, out[ival].key); + if ( !bcf_hdr_idinfo_exists(filter->hdr,BCF_HL_FLT,out[ival].hdr_id) ) + error("The filter \"%s\" not present in the VCF header\n", out[ival].key); + } + else + out[ival].hdr_id = -1; + out[ival].tag = out[ival].key; out[ival].key = NULL; + out[itok].hdr_id = out[ival].hdr_id; + continue; + } + } + filter->nsamples = filter->max_unpack&BCF_UN_FMT ? bcf_hdr_nsamples(filter->hdr) : 0; + for (i=0; insamples ) + { + out[i].pass_samples = (uint8_t*)malloc(filter->nsamples); + int j; + for (j=0; jnsamples; j++) out[i].pass_samples[j] = 1; + } + } + + if (0) filter_debug_print(out, NULL, nout); + + if ( mops ) free(ops); + filter->filters = out; + filter->nfilters = nout; + filter->flt_stack = (token_t **)malloc(sizeof(token_t*)*nout); + return filter; +} + +void filter_destroy(filter_t *filter) +{ + int i; + for (i=0; infilters; i++) + { + //if ( filter->filters[i].key ) free(filter->filters[i].key); + free(filter->filters[i].str_value); + free(filter->filters[i].tag); + free(filter->filters[i].values); + free(filter->filters[i].pass_samples); + if (filter->filters[i].hash) khash_str2int_destroy_free(filter->filters[i].hash); + if (filter->filters[i].regex) + { + regfree(filter->filters[i].regex); + free(filter->filters[i].regex); + } + } + free(filter->filters); + free(filter->flt_stack); + free(filter->str); + free(filter->tmpi); + free(filter->tmpf); + free(filter); +} + +int filter_test(filter_t *filter, bcf1_t *line, const uint8_t **samples) +{ + bcf_unpack(line, filter->max_unpack); + + int i, nstack = 0; + for (i=0; infilters; i++) + { + filter->filters[i].nsamples = 0; + filter->filters[i].nvalues = 0; + filter->filters[i].pass_site = -1; + + if ( filter->filters[i].tok_type == TOK_VAL ) + { + if ( filter->filters[i].setter ) // variable, query the VCF line + filter->filters[i].setter(filter, line, &filter->filters[i]); + else if ( filter->filters[i].key ) // string constant + { + filter->filters[i].str_value = filter->filters[i].key; + filter->filters[i].values[0] = filter->filters[i].values[0]; + filter->filters[i].nvalues = strlen(filter->filters[i].key); + } + else // numeric constant + { + filter->filters[i].values[0] = filter->filters[i].threshold; + filter->filters[i].nvalues = 1; + } + + filter->flt_stack[nstack++] = &filter->filters[i]; + continue; + } + else if ( filter->filters[i].tok_type == TOK_FUNC ) // all functions take only one argument + { + filter->filters[i].setter(filter, line, filter->flt_stack[nstack-1]); + continue; + } + if ( nstack<2 ) + error("Error occurred while processing the filter \"%s\" (1:%d)\n", filter->str,nstack); // too few values left on the stack + + int is_str = filter->flt_stack[nstack-1]->is_str + filter->flt_stack[nstack-2]->is_str; + + if ( filter->filters[i].tok_type == TOK_OR || filter->filters[i].tok_type == TOK_OR_VEC ) + { + if ( filter->flt_stack[nstack-1]->pass_site<0 || filter->flt_stack[nstack-2]->pass_site<0 ) + error("Error occurred while processing the filter \"%s\" (%d %d OR)\n", filter->str,filter->flt_stack[nstack-2]->pass_site,filter->flt_stack[nstack-1]->pass_site); + filter->flt_stack[nstack-2]->pass_site = vector_logic_or(filter->flt_stack[nstack-2],filter->flt_stack[nstack-1], filter->filters[i].tok_type); + nstack--; + continue; + } + if ( filter->filters[i].tok_type == TOK_AND || filter->filters[i].tok_type == TOK_AND_VEC ) + { + if ( filter->flt_stack[nstack-1]->pass_site<0 || filter->flt_stack[nstack-2]->pass_site<0 ) + error("Error occurred while processing the filter \"%s\" (%d %d AND)\n", filter->str,filter->flt_stack[nstack-2]->pass_site,filter->flt_stack[nstack-1]->pass_site); + filter->flt_stack[nstack-2]->pass_site = vector_logic_and(filter->flt_stack[nstack-2],filter->flt_stack[nstack-1], filter->filters[i].tok_type); + nstack--; + continue; + } + + if ( filter->filters[i].tok_type == TOK_ADD ) + { + VECTOR_ARITHMETICS(filter->flt_stack[nstack-2],filter->flt_stack[nstack-1],+); + nstack--; + continue; + } + else if ( filter->filters[i].tok_type == TOK_SUB ) + { + VECTOR_ARITHMETICS(filter->flt_stack[nstack-2],filter->flt_stack[nstack-1],-); + nstack--; + continue; + } + else if ( filter->filters[i].tok_type == TOK_MULT ) + { + VECTOR_ARITHMETICS(filter->flt_stack[nstack-2],filter->flt_stack[nstack-1],*); + nstack--; + continue; + } + else if ( filter->filters[i].tok_type == TOK_DIV ) + { + VECTOR_ARITHMETICS(filter->flt_stack[nstack-2],filter->flt_stack[nstack-1],/); + nstack--; + continue; + } + + int is_true = 0; + if ( filter->filters[i].comparator ) + is_true = filter->filters[i].comparator(filter->flt_stack[nstack-1],filter->flt_stack[nstack-2],filter->filters[i].tok_type,line); + else if ( !filter->flt_stack[nstack-1]->nvalues || !filter->flt_stack[nstack-2]->nvalues ) + { + int skip = 0; + if ( !filter->flt_stack[nstack-2]->is_missing && !filter->flt_stack[nstack-1]->is_missing ) skip = 1; + if ( filter->filters[i].tok_type != TOK_EQ && filter->filters[i].tok_type != TOK_NE ) skip = 1; + + if ( skip ) + filter->flt_stack[nstack-2]->nvalues = filter->flt_stack[nstack-2]->nsamples = 0; + else if ( filter->filters[i].tok_type == TOK_EQ ) + CMP_MISSING(filter->flt_stack[nstack-2],filter->flt_stack[nstack-1],==,is_true) + else if ( filter->filters[i].tok_type == TOK_NE ) + CMP_MISSING(filter->flt_stack[nstack-2],filter->flt_stack[nstack-1],!=,is_true) + } + else if ( filter->filters[i].tok_type == TOK_EQ ) + { + if ( filter->flt_stack[nstack-1]->comparator ) + is_true = filter->flt_stack[nstack-1]->comparator(filter->flt_stack[nstack-1],filter->flt_stack[nstack-2],TOK_EQ,line); + else if ( filter->flt_stack[nstack-2]->comparator ) + is_true = filter->flt_stack[nstack-2]->comparator(filter->flt_stack[nstack-2],filter->flt_stack[nstack-1],TOK_EQ,line); + else if ( is_str==2 ) // both are strings + is_true = cmp_vector_strings(filter->flt_stack[nstack-2],filter->flt_stack[nstack-1],TOK_EQ); + else if ( is_str==1 ) + error("Comparing string to numeric value: %s\n", filter->str); + else + CMP_VECTORS(filter->flt_stack[nstack-2],filter->flt_stack[nstack-1],==,is_true); + } + else if ( filter->filters[i].tok_type == TOK_NE ) + { + if ( filter->flt_stack[nstack-1]->comparator ) + is_true = filter->flt_stack[nstack-1]->comparator(filter->flt_stack[nstack-1],filter->flt_stack[nstack-2],TOK_NE,line); + else if ( filter->flt_stack[nstack-2]->comparator ) + is_true = filter->flt_stack[nstack-2]->comparator(filter->flt_stack[nstack-2],filter->flt_stack[nstack-1],TOK_NE,line); + else if ( is_str==2 ) + is_true = cmp_vector_strings(filter->flt_stack[nstack-2],filter->flt_stack[nstack-1],TOK_NE); + else if ( is_str==1 ) + error("Comparing string to numeric value: %s\n", filter->str); + else + CMP_VECTORS(filter->flt_stack[nstack-2],filter->flt_stack[nstack-1],!=,is_true); + } + else if ( filter->filters[i].tok_type == TOK_LIKE || filter->filters[i].tok_type == TOK_NLIKE ) + { + if ( is_str==2 ) + is_true = regex_vector_strings(filter->flt_stack[nstack-2],filter->flt_stack[nstack-1], filter->filters[i].tok_type == TOK_LIKE ? 0 : 1); + else + error("The regex operator can be used on strings only: %s\n", filter->str); + } + else if ( is_str>0 ) + error("Wrong operator in string comparison: %s [%s,%s]\n", filter->str, filter->flt_stack[nstack-1]->str_value, filter->flt_stack[nstack-2]->str_value); + else if ( filter->filters[i].tok_type == TOK_LE ) + CMP_VECTORS(filter->flt_stack[nstack-2],filter->flt_stack[nstack-1],<=,is_true) + else if ( filter->filters[i].tok_type == TOK_LT ) + CMP_VECTORS(filter->flt_stack[nstack-2],filter->flt_stack[nstack-1],<,is_true) + else if ( filter->filters[i].tok_type == TOK_BT ) + CMP_VECTORS(filter->flt_stack[nstack-2],filter->flt_stack[nstack-1],>,is_true) + else if ( filter->filters[i].tok_type == TOK_BE ) + CMP_VECTORS(filter->flt_stack[nstack-2],filter->flt_stack[nstack-1],>=,is_true) + else + error("FIXME: did not expect this .. tok_type %d = %d\n", i, filter->filters[i].tok_type); + + filter->flt_stack[nstack-2]->pass_site = is_true; + nstack--; + } + if ( nstack>1 ) error("Error occurred while processing the filter \"%s\" (2:%d)\n", filter->str,nstack); // too few values left on the stack + if ( samples ) + { + *samples = filter->max_unpack&BCF_UN_FMT ? filter->flt_stack[0]->pass_samples : NULL; + if ( *samples && !filter->flt_stack[0]->nsamples ) + { + for (i=0; insamples; i++) + filter->flt_stack[0]->pass_samples[i] = filter->flt_stack[0]->pass_site; + } + } + return filter->flt_stack[0]->pass_site; +} + +int filter_max_unpack(filter_t *flt) +{ + return flt->max_unpack; +} diff --git a/filter.h b/filter.h new file mode 100644 index 0000000..ccd3fe3 --- /dev/null +++ b/filter.h @@ -0,0 +1,52 @@ +/* filter.h -- filter expressions. + + Copyright (C) 2013-2014 Genome Research Ltd. + + Author: Petr Danecek + +Permission is hereby granted, free of charge, to any person obtaining a copy +of this software and associated documentation files (the "Software"), to deal +in the Software without restriction, including without limitation the rights +to use, copy, modify, merge, publish, distribute, sublicense, and/or sell +copies of the Software, and to permit persons to whom the Software is +furnished to do so, subject to the following conditions: + +The above copyright notice and this permission notice shall be included in +all copies or substantial portions of the Software. + +THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE +AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER +LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, +OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN +THE SOFTWARE. */ + +#ifndef __FILTER_H__ +#define __FILTER_H__ + +#include + +typedef struct _filter_t filter_t; + +/** + * @hdr: BCF header file + * @str: see the bcftools filter command help for description + */ +filter_t *filter_init(bcf_hdr_t *hdr, const char *str); + +void filter_destroy(filter_t *filter); + +/** + * filter_test() - test whether the BCF record passes the test + * @samples: if not NULL, a pointer to an array with samples statuses is + * stored in the location referenced by @samples. The pointer + * will be set to NULL if the FORMAT fields were not queried. + * Returns 1 if the expression is true and 0 if false. + */ +int filter_test(filter_t *filter, bcf1_t *rec, const uint8_t **samples); + +void filter_expression_info(FILE *fp); +int filter_max_unpack(filter_t *filter); + +#endif diff --git a/gvcf.c b/gvcf.c new file mode 100644 index 0000000..b82d658 --- /dev/null +++ b/gvcf.c @@ -0,0 +1,227 @@ +/* gvcf.c -- support for gVCF files. + + Copyright (C) 2014-2015 Genome Research Ltd. + + Author: Petr Danecek + +Permission is hereby granted, free of charge, to any person obtaining a copy +of this software and associated documentation files (the "Software"), to deal +in the Software without restriction, including without limitation the rights +to use, copy, modify, merge, publish, distribute, sublicense, and/or sell +copies of the Software, and to permit persons to whom the Software is +furnished to do so, subject to the following conditions: + +The above copyright notice and this permission notice shall be included in +all copies or substantial portions of the Software. + +THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL +THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER +LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING +FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER +DEALINGS IN THE SOFTWARE. */ + +#include "gvcf.h" +#include "bcftools.h" + +struct _gvcf_t +{ + int *dp_range, ndp_range; // per-sample DP ranges + int prev_range; // 0 if not in a block + int32_t *dp, mdp, *pl, mpl, npl; + int32_t *tmp, mtmp, *gts, ngts,mgts, nqsum,mqsum; + float *qsum; + int32_t rid, start, end, min_dp; + kstring_t als; + bcf1_t *line; +}; + +void gvcf_update_header(gvcf_t *gvcf, bcf_hdr_t *hdr) +{ + bcf_hdr_append(hdr,"##INFO="); + bcf_hdr_append(hdr,"##INFO="); +} + +gvcf_t *gvcf_init(const char *dp_ranges) +{ + gvcf_t *gvcf = (gvcf_t*) calloc(1,sizeof(gvcf_t)); + gvcf->line = bcf_init(); + + int n = 1; + const char *ss = dp_ranges; + while ( *ss ) + { + if ( *ss==',' ) n++; + ss++; + } + gvcf->ndp_range = n; + gvcf->dp_range = (int*) malloc(sizeof(int)*gvcf->ndp_range); + + n = 0; + ss = dp_ranges; + while ( *ss ) + { + char *se = (char*) ss; + gvcf->dp_range[n++] = strtol(ss,&se,10); + if ( se==ss ) return NULL; + if ( *se==',' && se[1] ) { ss = se+1; continue; } + else if ( !*se ) break; + return NULL; + } + return gvcf; +} + +void gvcf_destroy(gvcf_t *gvcf) +{ + free(gvcf->dp_range); + free(gvcf->dp); + free(gvcf->pl); + free(gvcf->tmp); + free(gvcf->qsum); + free(gvcf->gts); + free(gvcf->als.s); + if ( gvcf->line ) bcf_destroy(gvcf->line); + free(gvcf); +} + +bcf1_t *gvcf_write(gvcf_t *gvcf, htsFile *fh, bcf_hdr_t *hdr, bcf1_t *rec, int is_ref) +{ + int i, ret, nsmpl = bcf_hdr_nsamples(hdr); + int can_collapse = is_ref ? 1 : 0; + int32_t dp_range = 0, min_dp = 0; + + // No record and nothing to flush? + if ( !rec && !gvcf->prev_range ) return NULL; + + // Flush gVCF block if there are no more records, chr changed, a gap + // encountered, or other conditions not met (block broken by a non-ref or DP too low). + int needs_flush = can_collapse ? 0 : 1; + + + // Can the record be included in a gVCF block? That is, is this a ref-only site? + if ( rec && can_collapse ) + { + bcf_unpack(rec, BCF_UN_ALL); + + // per-sample depth + ret = bcf_get_format_int32(hdr, rec, "DP", &gvcf->tmp, &gvcf->mtmp); + if ( ret==nsmpl ) + { + min_dp = gvcf->tmp[0]; + for (i=1; i gvcf->tmp[i] ) min_dp = gvcf->tmp[i]; + + for (i=0; indp_range; i++) + if ( min_dp < gvcf->dp_range[i] ) break; + + dp_range = i; + if ( !dp_range ) + { + // leave the record unchanged, DP is too small. Alternatively, return NULL here + // to skip these sites + needs_flush = 1; + can_collapse = 0; + } + } + else + needs_flush = 1; // DP field not present + } + + if ( gvcf->prev_range && gvcf->prev_range!=dp_range ) needs_flush = 1; + if ( !rec || gvcf->rid!=rec->rid || rec->pos > gvcf->end+1 ) needs_flush = 1; + + // If prev_range is set, something can be flushed + if ( gvcf->prev_range && needs_flush ) + { + // mpileup can output two records with the same position, SNP and + // indel. Make sure the end position does not include the non-variant + // SNP position just before the indel. + if ( rec && rec->rid==gvcf->rid && rec->pos==gvcf->end ) gvcf->end--; + + gvcf->end++; // from 0-based to 1-based coordinate + + bcf_clear1(gvcf->line); + gvcf->line->rid = gvcf->rid; + gvcf->line->pos = gvcf->start; + gvcf->line->rlen = gvcf->end - gvcf->start; + bcf_update_alleles_str(hdr, gvcf->line, gvcf->als.s); + if ( gvcf->start+1 < gvcf->end ) // create gVCF record only if it spans at least two sites + bcf_update_info_int32(hdr, gvcf->line, "END", &gvcf->end, 1); + bcf_update_info_int32(hdr, gvcf->line, "MinDP", &gvcf->min_dp, 1); + if ( gvcf->nqsum>0 ) + bcf_update_info_float(hdr, gvcf->line, "QS", gvcf->qsum, gvcf->nqsum); + if ( gvcf->ngts ) + bcf_update_genotypes(hdr,gvcf->line,gvcf->gts,gvcf->ngts); + if ( gvcf->npl>0 ) + bcf_update_format_int32(hdr, gvcf->line, "PL", gvcf->pl, gvcf->npl); + bcf_update_format_int32(hdr, gvcf->line, "DP", gvcf->dp, nsmpl); + bcf_write1(fh, hdr, gvcf->line); + gvcf->prev_range = 0; + gvcf->rid = -1; + gvcf->npl = 0; + gvcf->nqsum = 0; + gvcf->ngts = 0; + + if ( !rec ) return NULL; // just flushing the buffer, this was last record + } + + if ( can_collapse ) + { + if ( !gvcf->prev_range ) + { + hts_expand(int32_t,nsmpl,gvcf->mdp,gvcf->dp); + memcpy(gvcf->dp,gvcf->tmp,nsmpl*sizeof(int32_t)); // tmp still contains DP from rec + gvcf->npl = bcf_get_format_int32(hdr, rec, "PL", &gvcf->pl, &gvcf->mpl); + + gvcf->nqsum = bcf_get_info_float(hdr,rec,"QS",&gvcf->qsum,&gvcf->mqsum); + gvcf->ngts = bcf_get_genotypes(hdr,rec,&gvcf->gts,&gvcf->mgts); + + gvcf->rid = rec->rid; + gvcf->start = rec->pos; + gvcf->als.l = 0; + kputs(rec->d.allele[0],&gvcf->als); + for (i=1; in_allele; i++) + { + kputc(',',&gvcf->als); + kputs(rec->d.allele[i],&gvcf->als); + } + gvcf->min_dp = min_dp; + } + else + { + if ( gvcf->min_dp > min_dp ) gvcf->min_dp = min_dp; + for (i=0; idp[i] > gvcf->tmp[i] ) gvcf->dp[i] = gvcf->tmp[i]; + ret = bcf_get_format_int32(hdr, rec, "PL", &gvcf->tmp, &gvcf->mtmp); + if ( ret>=0 ) + { + if ( ret!=nsmpl*3 ) error("Unexpected number of PL fields\n"); + for (i=0; ipl[3*i+1] > gvcf->tmp[3*i+1] ) + { + gvcf->pl[3*i+1] = gvcf->tmp[3*i+1]; + gvcf->pl[3*i+2] = gvcf->tmp[3*i+2]; + } + else if ( gvcf->pl[3*i+1]==gvcf->tmp[3*i+1] && gvcf->pl[3*i+2] > gvcf->tmp[3*i+2] ) + gvcf->pl[3*i+2] = gvcf->tmp[3*i+2]; + } + } + else + gvcf->npl = 0; + } + gvcf->prev_range = dp_range; + if ( bcf_get_info_int32(hdr,rec,"END",&gvcf->tmp,&gvcf->mtmp)==1 ) + gvcf->end = gvcf->tmp[0] - 1; // from 1-based to 0-based + else + gvcf->end = rec->pos; + return NULL; + } + + if ( is_ref && min_dp ) + bcf_update_info_int32(hdr, rec, "MinDP", &min_dp, 1); + + return rec; +} + diff --git a/gvcf.h b/gvcf.h new file mode 100644 index 0000000..784e1f6 --- /dev/null +++ b/gvcf.h @@ -0,0 +1,41 @@ +/* gvcf.[ch] - Helper functions for gVCF support + + The MIT License + + Copyright (c) 2015 Genome Research Ltd. + + Author: Petr Danecek + + Permission is hereby granted, free of charge, to any person obtaining a copy + of this software and associated documentation files (the "Software"), to deal + in the Software without restriction, including without limitation the rights + to use, copy, modify, merge, publish, distribute, sublicense, and/or sell + copies of the Software, and to permit persons to whom the Software is + furnished to do so, subject to the following conditions: + + The above copyright notice and this permission notice shall be included in + all copies or substantial portions of the Software. + + THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR + IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, + FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE + AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER + LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, + OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN + THE SOFTWARE. + + */ + +#ifndef __GVCF_H__ +#define __GVCF_H__ + +#include "bcftools.h" + +typedef struct _gvcf_t gvcf_t; + +gvcf_t *gvcf_init(const char *dp_ranges); +void gvcf_update_header(gvcf_t *gvcf, bcf_hdr_t *hdr); +bcf1_t *gvcf_write(gvcf_t *gvcf, htsFile *fh, bcf_hdr_t *hdr, bcf1_t *rec, int is_ref); +void gvcf_destroy(gvcf_t *gvcf); + +#endif diff --git a/hclust.c b/hclust.c new file mode 100644 index 0000000..692fa54 --- /dev/null +++ b/hclust.c @@ -0,0 +1,400 @@ +/* The MIT License + + Copyright (c) 2016 Genome Research Ltd. + + Author: Petr Danecek + + Permission is hereby granted, free of charge, to any person obtaining a copy + of this software and associated documentation files (the "Software"), to deal + in the Software without restriction, including without limitation the rights + to use, copy, modify, merge, publish, distribute, sublicense, and/or sell + copies of the Software, and to permit persons to whom the Software is + furnished to do so, subject to the following conditions: + + The above copyright notice and this permission notice shall be included in + all copies or substantial portions of the Software. + + THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR + IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, + FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE + AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER + LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, + OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN + THE SOFTWARE. + + */ + +#include +#include +#include +#include "bcftools.h" +#include "hclust.h" + +typedef struct _node_t +{ + struct _node_t *akid, *bkid, *next, *prev, *parent; + int id, idx; // id: unique node id; idx: current index to pdist + float value; // max pairwise dist of elements within the node +} +node_t; + +struct _hclust_t +{ + int ndat, nclust; // ndat: number of elements (pdist matrix size); nclust: current number of clusters + float *pdist; // pairwise cluster distances, diagonal matrix accessed via the PDIST macro + node_t *first, *last; // clusters are maintained in a double-linked list + node_t **rmme; // convenience array to remove all allocated nodes at the end + int nrmme; + kstring_t str; // (for debugging) pointer to str.s is returned by create_dot() + char **dbg; // (for debugging) created by create_list() via set_threshold() and returned by explain() + int ndbg, mdbg; +}; + +node_t *append_node(hclust_t *clust, int idx) +{ + node_t *node = (node_t*) calloc(1,sizeof(node_t)); + + clust->nclust++; + node->id = clust->nrmme; + node->idx = idx; + if ( !clust->first ) + { + clust->first = node; + clust->last = node; + } + else + { + node->prev = clust->last; + clust->last->next = node; + clust->last = node; + } + + if ( clust->nrmme >= clust->ndat*2 ) error("hclust fixme: %d vs %d\n",clust->nrmme,clust->ndat); + clust->rmme[clust->nrmme++] = node; + + return node; +} +void remove_node(hclust_t *clust, node_t *node) +{ + if ( node==clust->first ) clust->first = node->next; + if ( node==clust->last ) clust->last = node->prev; + if ( node->next ) node->next->prev = node->prev; + if ( node->prev ) node->prev->next = node->next; + clust->nclust--; +} + +#if DEBUG +void hclust_debug(hclust_t *clust) +{ + int i; + fprintf(stderr,"nrmme=%d nclust=%d\n", clust->nrmme,clust->nclust); + for (i=0; inrmme; i++) + { + node_t *node = clust->rmme[i]; + int akid = node->akid ? node->akid->id : -1; + int bkid = node->bkid ? node->bkid->id : -1; + int akidx = node->akid ? node->akid->idx : -1; + int bkidx = node->bkid ? node->bkid->idx : -1; + fprintf(stderr,"\t%d\t%d\t%f\t%d %d\t%d %d\n",node->id,node->idx,node->value,akid,bkid,akidx,bkidx); + } + + int j; + for (i=1; indat; i++) + { + int active = 0; + node_t *node = clust->first; + while (node) + { + if ( node->idx==i ) { active=1; break; } + node = node->next; + } + fprintf(stderr,"%2d%c ",i,active?'*':' '); + for (j=0; jpdist,i,j)==9 ) + fprintf(stderr," ----- "); + else + fprintf(stderr," %f", PDIST(clust->pdist,i,j)); + } + fprintf(stderr,"\n"); + } + for (j=0; jndat-1; j++) fprintf(stderr," %6d ",j); fprintf(stderr,"\n"); +} +#endif + +hclust_t *hclust_init(int n, float *pdist) +{ + hclust_t *clust = (hclust_t*) calloc(1,sizeof(hclust_t)); + clust->ndat = n; + clust->pdist = pdist; + clust->rmme = (node_t**) calloc(n*2,sizeof(node_t*)); + + // init clusters + int i; + for (i=0; indat; i++) append_node(clust,i); + + // build the tree + while ( clust->nclust>1 ) + { + // find two clusters with minimum distance + float min_value = HUGE_VAL; + node_t *iclust = clust->first->next; + node_t *min_iclust = NULL, *min_jclust = NULL; + while ( iclust ) + { + node_t *jclust = clust->first; + while ( jclust!=iclust ) + { + float value = PDIST(clust->pdist,iclust->idx,jclust->idx); + if ( value < min_value ) + { + min_value = value; + min_iclust = iclust; + min_jclust = jclust; + } + jclust = jclust->next; + } + iclust = iclust->next; + } + assert( min_iclust && min_jclust ); // pdist contains inf or nan, fix the caller + remove_node(clust,min_iclust); + remove_node(clust,min_jclust); + + // update the pairwise distances. We keep the matrix and as we are moving up the + // tree, we use fewer columns/rows as the number of clusters decreases: we reuse + // i-th and leave j-th unused. Inter-cluster distance is defined as maximum distance + // between pairwise distances of elements within the cluster. + iclust = clust->first; + while ( iclust ) + { + if ( PDIST(clust->pdist,iclust->idx,min_iclust->idx) < PDIST(clust->pdist,iclust->idx,min_jclust->idx) ) + PDIST(clust->pdist,iclust->idx,min_iclust->idx) = PDIST(clust->pdist,iclust->idx,min_jclust->idx); + iclust = iclust->next; + } + + node_t *node = append_node(clust,min_iclust->idx); + node->akid = min_iclust; + node->bkid = min_jclust; + node->value = min_value; + node->akid->parent = node; + node->bkid->parent = node; + } + + return clust; +} +void hclust_destroy(hclust_t *clust) +{ + int i; + for (i=0; inrmme; i++) free(clust->rmme[i]); + free(clust->rmme); + free(clust->dbg); + free(clust->str.s); + free(clust); +} + +char *hclust_create_dot(hclust_t *clust, char **labels, float th) +{ + clust->str.l = 0; + ksprintf(&clust->str,"digraph myGraph {"); + + int i; + for (i=0; inrmme; i++) + { + node_t *node = clust->rmme[i]; + if ( node->value ) + ksprintf(&clust->str,"\"%d\" [label=\"%f\"];", node->id,node->value); + else + ksprintf(&clust->str,"\"%d\" [label=\"%s\"];", node->id,labels[node->idx]); + } + for (i=0; inrmme; i++) + { + node_t *node = clust->rmme[i]; + if ( node->akid ) + { + if ( node->value >= th && node->akid && node->akid->value < th ) + ksprintf(&clust->str,"\"%d\" -> \"%d\" [color=\"#D43F3A\" penwidth=3];", node->id,node->akid->id); + else + ksprintf(&clust->str,"\"%d\" -> \"%d\";", node->id,node->akid->id); + } + + if ( node->bkid ) + { + if ( node->value >= th && node->bkid && node->bkid->value < th ) + ksprintf(&clust->str,"\"%d\" -> \"%d\" [color=\"#D43F3A\" penwidth=3];", node->id,node->bkid->id); + else + ksprintf(&clust->str,"\"%d\" -> \"%d\";", node->id,node->bkid->id); + } + } + ksprintf(&clust->str,"};"); + return clust->str.s; +} +char **hclust_explain(hclust_t *clust, int *nlines) +{ + clust->ndbg = 0; + char *beg = clust->str.s; + while ( *beg ) + { + char *end = beg; + while ( *end && *end!='\n' ) end++; + clust->ndbg++; + hts_expand(char*,clust->ndbg,clust->mdbg,clust->dbg); + clust->dbg[clust->ndbg-1] = beg; + if ( !*end ) break; + *end = 0; + beg = end + 1; + } + + *nlines = clust->ndbg; + return clust->dbg; +} + +cluster_t *append_cluster(node_t *node, cluster_t *cluster, int *nclust, node_t **stack) +{ + (*nclust)++; + cluster = (cluster_t*) realloc(cluster,sizeof(cluster_t)*(*nclust)); + cluster_t *clust = &cluster[*nclust-1]; + clust->nmemb = 0; + clust->memb = NULL; + clust->dist = node->value; + + int nstack = 1; + stack[0] = node; + + while ( nstack ) + { + node_t *node = stack[--nstack]; + node_t *akid = node->akid; + node_t *bkid = node->bkid; + if ( node->akid ) + { + stack[nstack++] = akid; + stack[nstack++] = bkid; + } + else + { + clust->nmemb++; + clust->memb = (int*) realloc(clust->memb,sizeof(int)*clust->nmemb); + clust->memb[clust->nmemb-1] = node->id; + } + } + return cluster; +} + +int cmp_nodes(const void *a, const void *b) +{ + const node_t *an = *((const node_t**) a); + const node_t *bn = *((const node_t**) b); + if ( an->value < bn->value ) return -1; + if ( an->value > bn->value ) return 1; + return 0; +} + +float calc_dev(node_t **dat, int n) +{ + float avg = 0, dev = 0; + int i; + for (i=0; ivalue; + avg /= n; + for (i=0; ivalue - avg)*(dat[i]->value - avg); + return sqrt(dev/n); +} + +/* + Heuristics to determine clustering cutoff: sort nodes by distance and + split into two groups by minimizing the standard deviation. + This works best when two elements from a single different sample are + included in the mix. + - min_inter_dist .. smaller values are always considered identical + - max_intra_dist .. larger values are always considered different + */ +float hclust_set_threshold(hclust_t *clust, float min_inter_dist, float max_intra_dist) +{ + node_t **dat = clust->rmme + clust->ndat; + int i, ndat = clust->nrmme - clust->ndat; + + qsort(dat, ndat, sizeof(dat), cmp_nodes); + + clust->str.l = 0; + float th, min_dev = HUGE_VAL; + int imin = -1; + for (i=0; i0 ) dev += calc_dev(dat,i); + if ( i+1value; + ksprintf(&clust->str,"DEV\t%f\t%f\n",th,dev); + if ( min_dev > dev && th >= min_inter_dist ) { min_dev = dev; imin = i; } + } + if ( max_intra_dist > 0 ) + th = max_intra_dist; // use fixed cutoff, the above was only for debugging output + else + { + // dynamic cutoff + max_intra_dist = fabs(max_intra_dist); + th = imin==-1 ? max_intra_dist : dat[imin]->value; + if ( th > max_intra_dist ) th = max_intra_dist; + } + ksprintf(&clust->str,"TH\t%f\n", th); + ksprintf(&clust->str,"MAX_DIST\t%f\n", dat[ndat-1]->value); + ksprintf(&clust->str,"MIN_INTER\t%f\n", min_inter_dist); + ksprintf(&clust->str,"MAX_INTRA\t%f\n", max_intra_dist); + return th; +} + +cluster_t *hclust_create_list(hclust_t *clust, float min_inter_dist, float *max_intra_dist, int *nclust) +{ + float cutoff = *max_intra_dist = hclust_set_threshold(clust, min_inter_dist, *max_intra_dist); + + node_t **stack = (node_t**) malloc(sizeof(node_t*)*clust->ndat); + node_t **tmp = (node_t**) malloc(sizeof(node_t*)*clust->ndat); + stack[0] = clust->first; + int nstack = 1; + + cluster_t *cluster = NULL; + int ncluster = 0; + + if ( stack[0]->value < cutoff ) + { + // all values are within the limits - create a single cluster + cluster = append_cluster(stack[0], cluster, &ncluster, tmp); + nstack = 0; + } + + while ( nstack ) + { + node_t *node = stack[--nstack]; + node_t *akid = node->akid; + node_t *bkid = node->bkid; + if ( !akid ) + { + cluster = append_cluster(node, cluster, &ncluster, tmp); + continue; + } + + if ( node->value >= cutoff && akid->value < cutoff ) + cluster = append_cluster(akid, cluster, &ncluster, tmp); + else + stack[nstack++] = akid; + + if ( node->value >= cutoff && bkid->value < cutoff ) + cluster = append_cluster(bkid, cluster, &ncluster, tmp); + else + stack[nstack++] = bkid; + } + + free(tmp); + free(stack); + + *nclust = ncluster; + return cluster; +} + +void hclust_destroy_list(cluster_t *clust, int nclust) +{ + int i; + for (i=0; i + + Permission is hereby granted, free of charge, to any person obtaining a copy + of this software and associated documentation files (the "Software"), to deal + in the Software without restriction, including without limitation the rights + to use, copy, modify, merge, publish, distribute, sublicense, and/or sell + copies of the Software, and to permit persons to whom the Software is + furnished to do so, subject to the following conditions: + + The above copyright notice and this permission notice shall be included in + all copies or substantial portions of the Software. + + THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR + IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, + FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE + AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER + LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, + OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN + THE SOFTWARE. + + */ + +/* + Simple hierarchical clustering +*/ + +#ifndef __HCLUST_H__ +#define __HCLUST_H__ + +#include + +typedef struct _hclust_t hclust_t; + +typedef struct +{ + float dist; + int nmemb, *memb; +} +cluster_t; + +#define PDIST(mat,a,b) (mat)[((a)>(b)?((a)*((a)-1)/2+(b)):((b)*((b)-1)/2+(a)))] + +/* + * hclust_init() - init and run clustering + * @n: number of elements + * @pdist: pairwise distances. The array will be modified by hclust and + * must exist until hclust_destroy() is called + */ +hclust_t *hclust_init(int n, float *pdist); +void hclust_destroy(hclust_t *clust); + +/* + * hclust_create_list() - returns a list of clusters + * @min_inter_dist: minimum inter-cluster distance. If smaller, elements are considered + * homogenous, belonging to the same cluster. + * @max_intra_dist: maximum intra-cluster distance allowed. If smaller than 0, + * the threshold can be heuristically lowered, otherwise considered + * a fixed cutoff. The pointer will be filled to the cutoff actually used. + */ +cluster_t *hclust_create_list(hclust_t *clust, float min_inter_dist, float *max_intra_dist, int *nclust); +void hclust_destroy_list(cluster_t *clust, int nclust); + +/* + * Access debugging data used in the decision making process. Note that this + * must be called immediately after hclust_create_list because other calls, + * such as hclust_create_dot(), invalidate the temporary data structures. + */ +char **hclust_explain(hclust_t *clust, int *nlines); + +char *hclust_create_dot(hclust_t *clust, char **labels, float th); + +#endif + diff --git a/khash_str2str.h b/khash_str2str.h new file mode 100644 index 0000000..4a5bd12 --- /dev/null +++ b/khash_str2str.h @@ -0,0 +1,106 @@ +/* khash_str2str.h -- C-string to C-string hash table. + + Copyright (C) 2014,2016 Genome Research Ltd. + + Author: Petr Danecek + +Permission is hereby granted, free of charge, to any person obtaining a copy +of this software and associated documentation files (the "Software"), to deal +in the Software without restriction, including without limitation the rights +to use, copy, modify, merge, publish, distribute, sublicense, and/or sell +copies of the Software, and to permit persons to whom the Software is +furnished to do so, subject to the following conditions: + +The above copyright notice and this permission notice shall be included in +all copies or substantial portions of the Software. + +THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL +THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER +LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING +FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER +DEALINGS IN THE SOFTWARE. */ + +#ifndef KHASH_STR2STR_H +#define KHASH_STR2STR_H + +#include + +KHASH_MAP_INIT_STR(str2str, const char*) + +/* + * Wrappers for khash dictionaries used by mpileup. + */ + +static inline void *khash_str2str_init(void) +{ + return kh_init(str2str); +} + +/* + * Destroy the hash structure, but not the keys + */ +static inline void khash_str2str_destroy(void *_hash) +{ + khash_t(str2str) *hash = (khash_t(str2str)*)_hash; + if (hash) kh_destroy(str2str, hash); // Note that strings are not freed. +} + +/* + * Destroys both the hash structure and the keys + */ +static inline void khash_str2str_destroy_free(void *_hash) +{ + khash_t(str2str) *hash = (khash_t(str2str)*)_hash; + khint_t k; + if (hash == 0) return; + for (k = 0; k < kh_end(hash); ++k) + if (kh_exist(hash, k)) free((char*)kh_key(hash, k)); + kh_destroy(str2str, hash); +} + +/* + * Destroys the hash structure, the keys and the values + */ +static inline void khash_str2str_destroy_free_all(void *_hash) +{ + khash_t(str2str) *hash = (khash_t(str2str)*)_hash; + khint_t k; + if (hash == 0) return; + for (k = 0; k < kh_end(hash); ++k) + if (kh_exist(hash, k)) + { + free((char*)kh_key(hash, k)); + free((char*)kh_val(hash, k)); + } + kh_destroy(str2str, hash); +} + +/* + * Returns value if key exists or NULL if not + */ +static inline char *khash_str2str_get(void *_hash, const char *str) +{ + khash_t(str2str) *hash = (khash_t(str2str)*)_hash; + khint_t k = kh_get(str2str, hash, str); + if ( k == kh_end(hash) ) return NULL; + return (char*)kh_val(hash, k); +} + +/* + * Set a new key,value pair. On success returns the bin index, on + * error -1 is returned. + */ +static inline int khash_str2str_set(void *_hash, const char *str, const char *value) +{ + khint_t k; + int ret; + khash_t(str2str) *hash = (khash_t(str2str)*)_hash; + if ( !hash ) return -1; + k = kh_put(str2str, hash, str, &ret); + kh_val(hash,k) = value; + return k; +} + +#endif diff --git a/kheap.h b/kheap.h new file mode 100644 index 0000000..ac2f9f9 --- /dev/null +++ b/kheap.h @@ -0,0 +1,171 @@ +/* The MIT License + + Copyright (C) 2016 Genome Research Ltd. + + Author: Petr Danecek + + Permission is hereby granted, free of charge, to any person obtaining a copy + of this software and associated documentation files (the "Software"), to deal + in the Software without restriction, including without limitation the rights + to use, copy, modify, merge, publish, distribute, sublicense, and/or sell + copies of the Software, and to permit persons to whom the Software is + furnished to do so, subject to the following conditions: + + The above copyright notice and this permission notice shall be included in + all copies or substantial portions of the Software. + + THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR + IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, + FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE + AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER + LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, + OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN + THE SOFTWARE. + + */ +/* + Usage example: + + #include "kheap.h" + + // First we prepare the user data to store, in this example it is a + // struct with a single element "key", and a comparator function + // "is_smaller". In this example the comparator defines a min heap (as + // opposed to a max heap). + typedef struct + { + uint32_t key; + } + data_t; + static inline int is_smaller(data_t *a, data_t *b) + { + return a->key < b->key ? 1 : 0; + } + data_t data[3] = { {3}, {2}, {1} }; + + + // Heap declaration, "mh" is an arbitrary string. The typedef is not + // required, it is just a convenience shortcut so that we can use + // "heap_t" instead of the generic "khp_mh_t" automatically created by + // the KHEAP_INIT macro. + KHEAP_INIT(mh, data_t, is_smaller) + typedef khp_mh_t heap_t; + + // Initialize the heap, insert the test data, then retrieve them back, + // sorted. Multiple heaps with the same name "mh" can be created and + // used simultaneously, as long as they all use the same data type + // "data_t". + heap_t *heap = khp_init(mh); + + for (int i=0; i<3; i++) + khp_insert(mh, heap, &data[i]); + + while (heap->ndat) + { + printf("%d\n", heap->dat[0].pos); + khp_delete(mh, heap); + } + + // Clean up + khp_destroy(mh, heap); + +*/ + +#ifndef __KHEAP_H__ +#define __KHEAP_H__ + +#include + +#ifndef kroundup32 +#define kroundup32(x) (--(x), (x)|=(x)>>1, (x)|=(x)>>2, (x)|=(x)>>4, (x)|=(x)>>8, (x)|=(x)>>16, ++(x)) +#endif + +#ifndef kh_inline +#ifdef _MSC_VER +#define kh_inline __inline +#else +#define kh_inline inline +#endif +#endif /* kh_inline */ + +#ifndef klib_unused +#if (defined __clang__ && __clang_major__ >= 3) || (defined __GNUC__ && __GNUC__ >= 3) +#define klib_unused __attribute__ ((__unused__)) +#else +#define klib_unused +#endif +#endif /* klib_unused */ + + +#define __KHEAP_TYPE(name, kheap_t) \ + typedef struct { \ + int ndat, mdat; \ + kheap_t *dat; \ + kheap_t tmp; \ + } khp_##name##_t; + +#define khp_parent(i) (((i)-1)/2) +#define khp_lchild(i) (2*(i)+1) +#define khp_rchild(i) (2*(i)+2) +#define khp_swap(hp,i,j) { \ + ((hp)->tmp) = ((hp)->dat[i]); \ + ((hp)->dat[i]) = ((hp)->dat[j]); \ + ((hp)->dat[j]) = ((hp)->tmp); \ + } + +#define __KHEAP_IMPL(name, SCOPE, kheap_t, __cmp) \ + SCOPE khp_##name##_t *khp_init_##name(void) \ + { \ + return (khp_##name##_t*)calloc(1, sizeof(khp_##name##_t)); \ + } \ + SCOPE void khp_destroy_##name(khp_##name##_t *heap) \ + { \ + if (heap) free(heap->dat); \ + free(heap); \ + } \ + SCOPE int khp_insert_##name(khp_##name##_t *heap, kheap_t *dat) \ + { \ + heap->ndat++; \ + if ( heap->ndat > heap->mdat ) \ + { \ + heap->mdat = heap->ndat; \ + kroundup32(heap->mdat); \ + heap->dat = (kheap_t*)realloc(heap->dat, heap->mdat*sizeof(kheap_t)); \ + } \ + int i = heap->ndat - 1; \ + while ( i && __cmp(dat,&heap->dat[khp_parent(i)]) ) \ + { \ + heap->dat[i] = heap->dat[khp_parent(i)]; \ + i = khp_parent(i); \ + } \ + heap->dat[i] = *dat; \ + return i; \ + } \ + SCOPE void khp_heapify_##name(khp_##name##_t *heap, int i) \ + { \ +/*todo: loop instead of a recursive function? */ \ + int extreme = khp_lchild(i) < heap->ndat && __cmp(&heap->dat[khp_lchild(i)],&heap->dat[i]) ? khp_lchild(i) : i; \ + if ( khp_rchild(i) < heap->ndat && __cmp(&heap->dat[khp_rchild(i)],&heap->dat[extreme]) ) extreme = khp_rchild(i); \ + if ( extreme != i ) \ + { \ + khp_swap(heap,i,extreme); \ + khp_heapify_##name(heap,extreme); \ + } \ + } \ + SCOPE void khp_delete_##name(khp_##name##_t *heap) \ + { \ + if ( !heap || !heap->ndat ) return; \ + heap->dat[0] = heap->dat[--heap->ndat]; \ + khp_heapify_##name(heap, 0); \ + } \ + +#define KHEAP_INIT(name, kheap_t, __cmp) \ + __KHEAP_TYPE(name, kheap_t) \ + __KHEAP_IMPL(name, static kh_inline klib_unused, kheap_t, __cmp) + +#define khp_init(name) khp_init_##name() +#define khp_destroy(name, heap) khp_destroy_##name(heap) +#define khp_insert(name, heap, dat) khp_insert_##name(heap, dat) +#define khp_delete(name, heap) khp_delete_##name(heap) + +#endif diff --git a/kmin.c b/kmin.c new file mode 100644 index 0000000..5b8193b --- /dev/null +++ b/kmin.c @@ -0,0 +1,209 @@ +/* The MIT License + + Copyright (c) 2008, 2010 by Attractive Chaos + + Permission is hereby granted, free of charge, to any person obtaining + a copy of this software and associated documentation files (the + "Software"), to deal in the Software without restriction, including + without limitation the rights to use, copy, modify, merge, publish, + distribute, sublicense, and/or sell copies of the Software, and to + permit persons to whom the Software is furnished to do so, subject to + the following conditions: + + The above copyright notice and this permission notice shall be + included in all copies or substantial portions of the Software. + + THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, + EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF + MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND + NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS + BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN + ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN + CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE + SOFTWARE. +*/ + +/* Hooke-Jeeves algorithm for nonlinear minimization + + Based on the pseudocodes by Bell and Pike (CACM 9(9):684-685), and + the revision by Tomlin and Smith (CACM 12(11):637-638). Both of the + papers are comments on Kaupe's Algorithm 178 "Direct Search" (ACM + 6(6):313-314). The original algorithm was designed by Hooke and + Jeeves (ACM 8:212-229). This program is further revised according to + Johnson's implementation at Netlib (opt/hooke.c). + + Hooke-Jeeves algorithm is very simple and it works quite well on a + few examples. However, it might fail to converge due to its heuristic + nature. A possible improvement, as is suggested by Johnson, may be to + choose a small r at the beginning to quickly approach to the minimum + and a large r at later step to hit the minimum. + */ + +#include +#include +#include +#include "kmin.h" + +static double __kmin_hj_aux(kmin_f func, int n, double *x1, void *data, double fx1, double *dx, int *n_calls) +{ + int k, j = *n_calls; + double ftmp; + for (k = 0; k != n; ++k) { + x1[k] += dx[k]; + ftmp = func(n, x1, data); ++j; + if (ftmp < fx1) fx1 = ftmp; + else { /* search the opposite direction */ + dx[k] = 0.0 - dx[k]; + x1[k] += dx[k] + dx[k]; + ftmp = func(n, x1, data); ++j; + if (ftmp < fx1) fx1 = ftmp; + else x1[k] -= dx[k]; /* back to the original x[k] */ + } + } + *n_calls = j; + return fx1; /* here: fx1=f(n,x1) */ +} + +double kmin_hj(kmin_f func, int n, double *x, void *data, double r, double eps, int max_calls) +{ + double fx, fx1, *x1, *dx, radius; + int k, n_calls = 0; + x1 = (double*)calloc(n, sizeof(double)); + dx = (double*)calloc(n, sizeof(double)); + for (k = 0; k != n; ++k) { /* initial directions, based on MGJ */ + dx[k] = fabs(x[k]) * r; + if (dx[k] == 0) dx[k] = r; + } + radius = r; + fx1 = fx = func(n, x, data); ++n_calls; + for (;;) { + memcpy(x1, x, n * sizeof(double)); /* x1 = x */ + fx1 = __kmin_hj_aux(func, n, x1, data, fx, dx, &n_calls); + while (fx1 < fx) { + for (k = 0; k != n; ++k) { + double t = x[k]; + dx[k] = x1[k] > x[k]? fabs(dx[k]) : 0.0 - fabs(dx[k]); + x[k] = x1[k]; + x1[k] = x1[k] + x1[k] - t; + } + fx = fx1; + if (n_calls >= max_calls) break; + fx1 = func(n, x1, data); ++n_calls; + fx1 = __kmin_hj_aux(func, n, x1, data, fx1, dx, &n_calls); + if (fx1 >= fx) break; + for (k = 0; k != n; ++k) + if (fabs(x1[k] - x[k]) > .5 * fabs(dx[k])) break; + if (k == n) break; + } + if (radius >= eps) { + if (n_calls >= max_calls) break; + radius *= r; + for (k = 0; k != n; ++k) dx[k] *= r; + } else break; /* converge */ + } + free(x1); free(dx); + return fx1; +} + +// I copied this function somewhere several years ago with some of my modifications, but I forgot the source. +double kmin_brent(kmin1_f func, double a, double b, void *data, double tol, double *xmin) +{ + double bound, u, r, q, fu, tmp, fa, fb, fc, c; + const double gold1 = 1.6180339887; + const double gold2 = 0.3819660113; + const double tiny = 1e-20; + const int max_iter = 100; + + double e, d, w, v, mid, tol1, tol2, p, eold, fv, fw; + int iter; + + fa = func(a, data); fb = func(b, data); + if (fb > fa) { // swap, such that f(a) > f(b) + tmp = a; a = b; b = tmp; + tmp = fa; fa = fb; fb = tmp; + } + c = b + gold1 * (b - a), fc = func(c, data); // golden section extrapolation + while (fb > fc) { + bound = b + 100.0 * (c - b); // the farthest point where we want to go + r = (b - a) * (fb - fc); + q = (b - c) * (fb - fa); + if (fabs(q - r) < tiny) { // avoid 0 denominator + tmp = q > r? tiny : 0.0 - tiny; + } else tmp = q - r; + u = b - ((b - c) * q - (b - a) * r) / (2.0 * tmp); // u is the parabolic extrapolation point + if ((b > u && u > c) || (b < u && u < c)) { // u lies between b and c + fu = func(u, data); + if (fu < fc) { // (b,u,c) bracket the minimum + a = b; b = u; fa = fb; fb = fu; + break; + } else if (fu > fb) { // (a,b,u) bracket the minimum + c = u; fc = fu; + break; + } + u = c + gold1 * (c - b); fu = func(u, data); // golden section extrapolation + } else if ((c > u && u > bound) || (c < u && u < bound)) { // u lies between c and bound + fu = func(u, data); + if (fu < fc) { // fb > fc > fu + b = c; c = u; u = c + gold1 * (c - b); + fb = fc; fc = fu; fu = func(u, data); + } else { // (b,c,u) bracket the minimum + a = b; b = c; c = u; + fa = fb; fb = fc; fc = fu; + break; + } + } else if ((u > bound && bound > c) || (u < bound && bound < c)) { // u goes beyond the bound + u = bound; fu = func(u, data); + } else { // u goes the other way around, use golden section extrapolation + u = c + gold1 * (c - b); fu = func(u, data); + } + a = b; b = c; c = u; + fa = fb; fb = fc; fc = fu; + } + if (a > c) u = a, a = c, c = u; // swap + + // now, afb and fb tol1) { + // related to parabolic interpolation + r = (b - w) * (fb - fv); + q = (b - v) * (fb - fw); + p = (b - v) * q - (b - w) * r; + q = 2.0 * (q - r); + if (q > 0.0) p = 0.0 - p; + else q = 0.0 - q; + eold = e; e = d; + if (fabs(p) >= fabs(0.5 * q * eold) || p <= q * (a - b) || p >= q * (c - b)) { + d = gold2 * (e = (b >= mid ? a - b : c - b)); + } else { + d = p / q; u = b + d; // actual parabolic interpolation happens here + if (u - a < tol2 || c - u < tol2) + d = (mid > b)? tol1 : 0.0 - tol1; + } + } else d = gold2 * (e = (b >= mid ? a - b : c - b)); // golden section interpolation + u = fabs(d) >= tol1 ? b + d : b + (d > 0.0? tol1 : -tol1); + fu = func(u, data); + if (fu <= fb) { // u is the minimum point so far + if (u >= b) a = b; + else c = b; + v = w; w = b; b = u; fv = fw; fw = fb; fb = fu; + } else { // adjust (a,c) and (u,v,w) + if (u < b) a = u; + else c = u; + if (fu <= fw || w == b) { + v = w; w = u; + fv = fw; fw = fu; + } else if (fu <= fv || v == b || v == w) { + v = u; fv = fu; + } + } + } + *xmin = b; + return fb; +} diff --git a/kmin.h b/kmin.h new file mode 100644 index 0000000..6feba45 --- /dev/null +++ b/kmin.h @@ -0,0 +1,46 @@ +/* + Copyright (c) 2008, 2010 by Attractive Chaos + + Permission is hereby granted, free of charge, to any person obtaining + a copy of this software and associated documentation files (the + "Software"), to deal in the Software without restriction, including + without limitation the rights to use, copy, modify, merge, publish, + distribute, sublicense, and/or sell copies of the Software, and to + permit persons to whom the Software is furnished to do so, subject to + the following conditions: + + The above copyright notice and this permission notice shall be + included in all copies or substantial portions of the Software. + + THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, + EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF + MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND + NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS + BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN + ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN + CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE + SOFTWARE. +*/ + +#ifndef KMIN_H +#define KMIN_H + +#define KMIN_RADIUS 0.5 +#define KMIN_EPS 1e-7 +#define KMIN_MAXCALL 50000 + +typedef double (*kmin_f)(int, double*, void*); +typedef double (*kmin1_f)(double, void*); + +#ifdef __cplusplus +extern "C" { +#endif + + double kmin_hj(kmin_f func, int n, double *x, void *data, double r, double eps, int max_calls); + double kmin_brent(kmin1_f func, double a, double b, void *data, double tol, double *xmin); + +#ifdef __cplusplus +} +#endif + +#endif diff --git a/main.c b/main.c new file mode 100644 index 0000000..9350ff8 --- /dev/null +++ b/main.c @@ -0,0 +1,274 @@ +/* main.c -- main bcftools command front-end. + + Copyright (C) 2012-2016 Genome Research Ltd. + + Author: Petr Danecek + +Permission is hereby granted, free of charge, to any person obtaining a copy +of this software and associated documentation files (the "Software"), to deal +in the Software without restriction, including without limitation the rights +to use, copy, modify, merge, publish, distribute, sublicense, and/or sell +copies of the Software, and to permit persons to whom the Software is +furnished to do so, subject to the following conditions: + +The above copyright notice and this permission notice shall be included in +all copies or substantial portions of the Software. + +THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE +AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER +LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, +OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN +THE SOFTWARE. */ + +#include +#include +#include +#include +#include +#include +#include "version.h" +#include "bcftools.h" + +int main_tabix(int argc, char *argv[]); +int main_vcfindex(int argc, char *argv[]); +int main_vcfstats(int argc, char *argv[]); +int main_vcfisec(int argc, char *argv[]); +int main_vcfmerge(int argc, char *argv[]); +int main_vcfquery(int argc, char *argv[]); +int main_vcffilter(int argc, char *argv[]); +int main_vcfsom(int argc, char *argv[]); +int main_vcfnorm(int argc, char *argv[]); +int main_vcfgtcheck(int argc, char *argv[]); +int main_vcfview(int argc, char *argv[]); +int main_vcfcall(int argc, char *argv[]); +int main_vcfannotate(int argc, char *argv[]); +int main_vcfroh(int argc, char *argv[]); +int main_vcfconcat(int argc, char *argv[]); +int main_reheader(int argc, char *argv[]); +int main_vcfconvert(int argc, char *argv[]); +int main_vcfcnv(int argc, char *argv[]); +#if USE_GPL +int main_polysomy(int argc, char *argv[]); +#endif +int main_plugin(int argc, char *argv[]); +int main_consensus(int argc, char *argv[]); +int main_csq(int argc, char *argv[]); +int bam_mpileup(int argc, char *argv[]); + +typedef struct +{ + int (*func)(int, char*[]); + const char *alias, *help; +} +cmd_t; + +static cmd_t cmds[] = +{ + { .func = NULL, + .alias = "Indexing", + .help = NULL + }, + { .func = main_vcfindex, + .alias = "index", + .help = "index VCF/BCF files" + }, + { .func = main_tabix, + .alias = "tabix", + .help = "-tabix for BGZF'd BED, GFF, SAM, VCF and more" // do not advertise; only keep here for testing + }, + + { .func = NULL, + .alias = "VCF/BCF manipulation", + .help = NULL + }, + + { .func = main_vcfannotate, + .alias = "annotate", + .help = "annotate and edit VCF/BCF files", + }, + { .func = main_vcfconcat, + .alias = "concat", + .help = "concatenate VCF/BCF files from the same set of samples" + }, + { .func = main_vcfconvert, + .alias = "convert", + .help = "convert VCF/BCF files to different formats and back" + }, + { .func = main_vcfisec, + .alias = "isec", + .help = "intersections of VCF/BCF files" + }, + { .func = main_vcfmerge, + .alias = "merge", + .help = "merge VCF/BCF files files from non-overlapping sample sets" + }, + { .func = main_vcfnorm, + .alias = "norm", + .help = "left-align and normalize indels" + }, + { .func = main_plugin, + .alias = "plugin", + .help = "user-defined plugins" + }, + { .func = main_vcfquery, + .alias = "query", + .help = "transform VCF/BCF into user-defined formats" + }, + { .func = main_reheader, + .alias = "reheader", + .help = "modify VCF/BCF header, change sample names" + }, + { .func = main_vcfview, + .alias = "view", + .help = "VCF/BCF conversion, view, subset and filter VCF/BCF files" + }, + + { .func = NULL, + .alias = "VCF/BCF analysis", + .help = NULL + }, + + { .func = main_vcfcall, + .alias = "call", + .help = "SNP/indel calling" + }, + { .func = main_consensus, + .alias = "consensus", + .help = "create consensus sequence by applying VCF variants" + }, + { .func = main_vcfcnv, + .alias = "cnv", + .help = "HMM CNV calling" + }, + { .func = main_csq, + .alias = "csq", + .help = "call variation consequences" + }, + { .func = main_vcffilter, + .alias = "filter", + .help = "filter VCF/BCF files using fixed thresholds" + }, + { .func = main_vcfgtcheck, + .alias = "gtcheck", + .help = "check sample concordance, detect sample swaps and contamination" + }, + { .func = bam_mpileup, + .alias = "mpileup", + .help = "multi-way pileup producing genotype likelihoods" + }, +#if USE_GPL + { .func = main_polysomy, + .alias = "polysomy", + .help = "detect number of chromosomal copies", + }, +#endif + { .func = main_vcfroh, + .alias = "roh", + .help = "identify runs of autozygosity (HMM)", + }, + { .func = main_vcfstats, + .alias = "stats", + .help = "produce VCF/BCF stats" + }, + + { .func = main_vcfsom, + .alias = "som", + .help = "-filter using Self-Organized Maps (experimental)" // do not advertise + + }, + { .func = NULL, + .alias = NULL, + .help = NULL + } +}; + +char *bcftools_version(void) +{ + return BCFTOOLS_VERSION; +} + +static void usage(FILE *fp) +{ + fprintf(fp, "\n"); + fprintf(fp, "Program: bcftools (Tools for variant calling and manipulating VCFs and BCFs)\n"); +#if USE_GPL + fprintf(fp, "License: GNU GPLv3+, due to use of the GNU Scientific Library\n"); +#endif + fprintf(fp, "Version: %s (using htslib %s)\n", bcftools_version(), hts_version()); + fprintf(fp, "\n"); + fprintf(fp, "Usage: bcftools [--version|--version-only] [--help] \n"); + fprintf(fp, "\n"); + fprintf(fp, "Commands:\n"); + + int i = 0; + const char *sep = NULL; + while (cmds[i].alias) + { + if ( !cmds[i].func ) sep = cmds[i].alias; + if ( sep ) + { + fprintf(fp, "\n -- %s\n", sep); + sep = NULL; + } + if ( cmds[i].func && cmds[i].help[0]!='-' ) fprintf(fp, " %-12s %s\n", cmds[i].alias, cmds[i].help); + i++; + } + fprintf(fp,"\n"); + fprintf(fp, + " Most commands accept VCF, bgzipped VCF, and BCF with the file type detected\n" + " automatically even when streaming from a pipe. Indexed VCF and BCF will work\n" + " in all situations. Un-indexed VCF and BCF and streams will work in most but\n" + " not all situations.\n"); + fprintf(fp,"\n"); +} + +int main(int argc, char *argv[]) +{ + if (argc < 2) { usage(stderr); return 1; } + + if (strcmp(argv[1], "version") == 0 || strcmp(argv[1], "--version") == 0 || strcmp(argv[1], "-v") == 0) { + printf("bcftools %s\nUsing htslib %s\nCopyright (C) 2016 Genome Research Ltd.\n", bcftools_version(), hts_version()); +#if USE_GPL + printf("License GPLv3+: GNU GPL version 3 or later \n"); +#else + printf("License Expat: The MIT/Expat license\n"); +#endif + printf("This is free software: you are free to change and redistribute it.\nThere is NO WARRANTY, to the extent permitted by law.\n"); + return 0; + } + else if (strcmp(argv[1], "--version-only") == 0) { + printf("%s+htslib-%s\n", bcftools_version(), hts_version()); + return 0; + } + else if (strcmp(argv[1], "help") == 0 || strcmp(argv[1], "--help") == 0 || strcmp(argv[1], "-h") == 0) { + if (argc == 2) { usage(stdout); return 0; } + // Otherwise change "bcftools help COMMAND [...]" to "bcftools COMMAND"; + // main_xyz() functions by convention display the subcommand's usage + // when invoked without any arguments. + argv++; + argc = 2; + } + else if ( argv[1][0]=='+' ) + { + // "bcftools plugin name" can be run as "bcftools +name" + argv[1]++; + argv[0] = "plugin"; + argv--; + argc++; + } + + int i = 0; + while (cmds[i].alias) + { + if (cmds[i].func && strcmp(argv[1],cmds[i].alias)==0) + { + return cmds[i].func(argc-1,argv+1); + } + i++; + } + fprintf(stderr, "[E::%s] unrecognized command '%s'\n", __func__, argv[1]); + return 1; +} + diff --git a/mcall.c b/mcall.c new file mode 100644 index 0000000..7f7515f --- /dev/null +++ b/mcall.c @@ -0,0 +1,1579 @@ +/* mcall.c -- multiallelic and rare variant calling. + + Copyright (C) 2012-2016 Genome Research Ltd. + + Author: Petr Danecek + +Permission is hereby granted, free of charge, to any person obtaining a copy +of this software and associated documentation files (the "Software"), to deal +in the Software without restriction, including without limitation the rights +to use, copy, modify, merge, publish, distribute, sublicense, and/or sell +copies of the Software, and to permit persons to whom the Software is +furnished to do so, subject to the following conditions: + +The above copyright notice and this permission notice shall be included in +all copies or substantial portions of the Software. + +THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE +AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER +LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, +OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN +THE SOFTWARE. */ + +#include +#include +#include "call.h" + +// Using priors for GTs does not seem to be mathematically justified. Although +// it seems effective in removing false calls, it also flips a significant +// proportion of HET genotypes. Better is to filter by FORMAT/GQ using +// `bcftools filter`. +#define USE_PRIOR_FOR_GTS 0 + +// Go with uniform PLs for samples with no coverage. If unset, missing +// genotypes is reported instead. +#define FLAT_PDG_FOR_MISSING 0 + +// Estimate QS (combined quality and allele frequencies) from PLs +#define QS_FROM_PDG 0 + + +void qcall_init(call_t *call) { return; } +void qcall_destroy(call_t *call) { return; } +int qcall(call_t *call, bcf1_t *rec) +{ + // QCall format: + // chromosome, position, reference allele, depth, mapping quality, 0, .. + error("TODO: qcall output\n"); + return 0; +} + +void call_init_pl2p(call_t *call) +{ + int i; + for (i=0; i<256; i++) + call->pl2p[i] = pow(10., -i/10.); +} + +// Macros for accessing call->trio and call->ntrio +#define FTYPE_222 0 // family type: all diploid +#define FTYPE_121 1 // chrX, the child is a boy +#define FTYPE_122 2 // chrX, a girl +#define FTYPE_101 3 // chrY, boy +#define FTYPE_100 4 // chrY, girl + +#define GT_SKIP 0xf // empty genotype (chrY in females) + +#define IS_POW2(x) (!((x) & ((x) - 1))) // zero is permitted +#define IS_HOM(x) IS_POW2(x) + +// Pkij = P(k|i,j) tells how likely it is to be a het if the parents +// are homs etc. The consistency of i,j,k has been already checked. +// Parameters are alleles and ploidy of father, mother, kid +// Returns 2/Pkij. +int calc_Pkij(int fals, int mals, int kals, int fpl, int mpl, int kpl) +{ + int als = fals|mals|kals; + if ( IS_HOM(als) ) return 2; // all are the same: child must be a HOM, P=1 + + if ( fpl==1 ) + { + if ( kpl==1 ) // chr X, the child is a boy, the copy is inherited from the mother + { + if ( IS_HOM(mals) ) return 2; // 0 11 -> P(1) = 1 + return 4; // 0 01 -> P(0) = P(1) = 1/2 + } + // chr X, the child is a girl + if ( IS_HOM(mals) ) return 2; // 0 11 -> P(01) = 1 + return 4; // 0 01 -> P(00) = P(01) = 1/2 + } + + if ( IS_HOM(fals) && IS_HOM(mals) ) return 2; // 00 11 01, the child must be a HET, P=1 + if ( !IS_HOM(fals) && !IS_HOM(mals) ) + { + if ( IS_HOM(kals) ) return 8; // 01 01 00 or 01 01 11, P(k=HOM) = 1/4 + return 4; // 01 01 01, P(k=HET) = 1/2 + } + return 4; // 00 01, P(k=HET) = P(k=HOM) = 1/2 +} + +// Initialize ntrio and trio: ntrio lists the number of possible +// genotypes given combination of haploid/diploid genomes and the +// number of alleles. trio lists allowed genotype combinations: +// 4bit: 2/Pkij, 4: father, 4: mother, 4: child +// See also mcall_call_trio_genotypes() +// +static void mcall_init_trios(call_t *call) +{ + if ( call->prior_AN ) + { + int id = bcf_hdr_id2int(call->hdr,BCF_DT_ID,call->prior_AN); + if ( id==-1 ) error("No such tag \"%s\"\n", call->prior_AN); + if ( !bcf_hdr_idinfo_exists(call->hdr,BCF_HL_FMT,id) ) error("No such FORMAT tag \"%s\"\n", call->prior_AN); + id = bcf_hdr_id2int(call->hdr,BCF_DT_ID,call->prior_AC); + if ( id==-1 ) error("No such tag \"%s\"\n", call->prior_AC); + if ( !bcf_hdr_idinfo_exists(call->hdr,BCF_HL_FMT,id) ) error("No such FORMAT tag \"%s\"\n", call->prior_AC); + } + + // 23, 138, 478 possible diploid trio genotypes with 2, 3, 4 alleles + call->ntrio[FTYPE_222][2] = 15; call->ntrio[FTYPE_222][3] = 78; call->ntrio[FTYPE_222][4] = 250; + call->ntrio[FTYPE_121][2] = 8; call->ntrio[FTYPE_121][3] = 27; call->ntrio[FTYPE_121][4] = 64; + call->ntrio[FTYPE_122][2] = 8; call->ntrio[FTYPE_122][3] = 27; call->ntrio[FTYPE_122][4] = 64; + call->ntrio[FTYPE_101][2] = 2; call->ntrio[FTYPE_101][3] = 3; call->ntrio[FTYPE_101][4] = 4; + call->ntrio[FTYPE_100][2] = 2; call->ntrio[FTYPE_100][3] = 3; call->ntrio[FTYPE_100][4] = 4; + + int nals, itype; + for (itype=0; itype<=4; itype++) + { + for (nals=2; nals<=4; nals++) + call->trio[itype][nals] = (uint16_t*) malloc(sizeof(uint16_t)*call->ntrio[itype][nals]); + } + + // max 10 possible diploid genotypes + int gts[10]; + for (nals=2; nals<=4; nals++) + { + int i,j,k, n = 0, ngts = 0; + for (i=0; itrio[FTYPE_222][nals][n++] = Pkij<<12 | i<<8 | j<<4 | k; // father, mother, child + } + assert( n==call->ntrio[FTYPE_222][nals] ); + + // 121: chrX, boy + n = 0; + for (i=0; itrio[FTYPE_121][nals][n++] = Pkij<<12 | i<<8 | j<<4 | k; + } + assert( n==call->ntrio[FTYPE_121][nals] ); + + // 122: chrX, girl + n = 0; + for (i=0; itrio[FTYPE_122][nals][n++] = Pkij<<12 | i<<8 | j<<4 | k; + } + assert( n==call->ntrio[FTYPE_122][nals] ); + + // 101: chrY, boy + n = 0; + for (i=0; itrio[FTYPE_101][nals][n++] = 1<<12 | i<<8 | GT_SKIP<<4 | k; + } + assert( n==call->ntrio[FTYPE_101][nals] ); + + // 100: chrY, girl + n = 0; + for (i=0; itrio[FTYPE_100][nals][n++] = 1<<12 | i<<8 | GT_SKIP<<4 | GT_SKIP; + } + assert( n==call->ntrio[FTYPE_100][nals] ); + + } + call->GLs = (double*) calloc(bcf_hdr_nsamples(call->hdr)*10,sizeof(double)); + + int i, j; + for (i=0; infams; i++) + { + family_t *fam = &call->fams[i]; + int ploidy[3]; + for (j=0; j<3; j++) + ploidy[j] = call->ploidy[fam->sample[j]]; + + if ( ploidy[FATHER]==2 ) // not X, not Y + { + if ( ploidy[MOTHER]!=2 || ploidy[CHILD]!=2 ) + error("Incorrect ploidy: %d %d %d\n", ploidy[FATHER],ploidy[MOTHER],ploidy[CHILD]); + fam->type = FTYPE_222; + continue; + } + if ( ploidy[FATHER]!=1 || ploidy[MOTHER]==1 ) + error("Incorrect ploidy: %d %d %d\n", ploidy[FATHER],ploidy[MOTHER],ploidy[CHILD]); + if ( ploidy[MOTHER]==2 ) // X + { + if ( ploidy[CHILD]==0 ) + error("Incorrect ploidy: %d %d %d\n", ploidy[FATHER],ploidy[MOTHER],ploidy[CHILD]); + fam->type = ploidy[CHILD]==2 ? FTYPE_122 : FTYPE_121; // a girl or a boy + } + else // Y + { + if ( ploidy[CHILD]==2 ) + error("Incorrect ploidy: %d %d %d\n", ploidy[FATHER],ploidy[MOTHER],ploidy[CHILD]); + fam->type = ploidy[CHILD]==0 ? FTYPE_100 : FTYPE_101; // a girl or a boy + } + } +} +static void mcall_destroy_trios(call_t *call) +{ + int i, j; + for (i=2; i<=4; i++) + for (j=0; j<=4; j++) + free(call->trio[j][i]); +} + +void mcall_init(call_t *call) +{ + call_init_pl2p(call); + + call->nqsum = 5; + call->qsum = (float*) malloc(sizeof(float)*call->nqsum); // will be expanded later if ncessary + call->nals_map = 5; + call->als_map = (int*) malloc(sizeof(int)*call->nals_map); + call->npl_map = 5*(5+1)/2; // will be expanded later if necessary + call->pl_map = (int*) malloc(sizeof(int)*call->npl_map); + call->gts = (int32_t*) calloc(bcf_hdr_nsamples(call->hdr)*2,sizeof(int32_t)); // assuming at most diploid everywhere + + if ( call->flag & CALL_CONSTR_TRIO ) + { + call->cgts = (int32_t*) calloc(bcf_hdr_nsamples(call->hdr),sizeof(int32_t)); + call->ugts = (int32_t*) calloc(bcf_hdr_nsamples(call->hdr),sizeof(int32_t)); + mcall_init_trios(call); + bcf_hdr_append(call->hdr,"##FORMAT="); + bcf_hdr_append(call->hdr,"##FORMAT="); + } + if ( call->flag & CALL_CONSTR_ALLELES ) call->vcmp = vcmp_init(); + + bcf_hdr_append(call->hdr,"##FORMAT="); + if ( call->output_tags & CALL_FMT_GQ ) + bcf_hdr_append(call->hdr,"##FORMAT="); + if ( call->output_tags & CALL_FMT_GP ) + bcf_hdr_append(call->hdr,"##FORMAT="); + if ( call->output_tags & (CALL_FMT_GQ|CALL_FMT_GP) ) + call->GQs = (int32_t*) malloc(sizeof(int32_t)*bcf_hdr_nsamples(call->hdr)); + bcf_hdr_append(call->hdr,"##INFO="); + bcf_hdr_append(call->hdr,"##INFO="); + bcf_hdr_append(call->hdr,"##INFO="); + bcf_hdr_append(call->hdr,"##INFO="); + bcf_hdr_append(call->hdr,"##INFO="); + bcf_hdr_append(call->hdr,"##INFO="); + + // init the prior + if ( call->theta>0 ) + { + int i, n = 0; + if ( !call->ploidy ) n = 2*bcf_hdr_nsamples(call->hdr); // all are diploid + else + { + for (i=0; ihdr); i++) + n += call->ploidy[i]; + } + // Watterson factor, here aM_1 = aM_2 = 1 + double aM = 1; + for (i=2; itheta *= aM; + if ( call->theta >= 1 ) + { + fprintf(stderr,"The prior is too big (theta*aM=%.2f), going with 0.99\n", call->theta); + call->theta = 0.99; + } + call->theta = log(call->theta); + } + + return; +} + +void mcall_destroy(call_t *call) +{ + if (call->vcmp) vcmp_destroy(call->vcmp); + free(call->itmp); + mcall_destroy_trios(call); + free(call->GPs); + free(call->GLs); + free(call->GQs); + free(call->anno16); + free(call->PLs); + free(call->qsum); + free(call->als_map); + free(call->pl_map); + free(call->gts); free(call->cgts); free(call->ugts); + free(call->pdg); + free(call->als); + free(call->ac); + return; +} + + +// Inits P(D|G): convert PLs from log space and normalize. In case of zero +// depth, missing PLs are all zero. In this case, pdg's are set to 0 +// so that the corresponding genotypes can be set as missing and the +// qual calculation is not affected. +// Missing values are replaced by generic likelihoods when X (unseen allele) is +// present. +// NB: While the -m callig model uses the pdgs in canonical order, +// the original samtools -c calling code uses pdgs in reverse order (AA comes +// first, RR last). +// NB: Ploidy is not taken into account here, which is incorrect. +void set_pdg(double *pl2p, int *PLs, double *pdg, int n_smpl, int n_gt, int unseen) +{ + int i, j, nals; + + // find out the number of alleles, expecting diploid genotype likelihoods + bcf_gt2alleles(n_gt-1, &i, &nals); + assert( i==nals ); + nals++; + + for (i=0; ipdg; + int ngts = rec->n_allele*(rec->n_allele+1)/2; + int i,nsmpl = bcf_hdr_nsamples(call->hdr); + + hts_expand(float,rec->n_allele,call->nqsum,call->qsum); + for (i=0; in_allele; i++) call->qsum[i] = 0; + + for (i=0; in_allele; a++) + { + for (b=0; b<=a; b++) + { + call->qsum[a] += pdg[k]; + call->qsum[b] += pdg[k]; + k++; + } + } + pdg += ngts; + } + float sum = 0; + for (i=0; in_allele; i++) sum += call->qsum[i]; + if ( sum ) for (i=0; in_allele; i++) call->qsum[i] /= sum; +} + +// Create mapping between old and new (trimmed) alleles +void init_allele_trimming_maps(call_t *call, int als, int nals) +{ + int i, j; + + // als_map: old(i) -> new(j) + for (i=0, j=0; ials_map[i] = j++; + else call->als_map[i] = -1; + } + + if ( !call->pl_map ) return; + + // pl_map: new(k) -> old(l) + int k = 0, l = 0; + for (i=0; ipl_map[k++] = l; + l++; + } + } +} + +double binom_dist(int N, double p, int k) +{ + int mean = (int) (N*p); + if ( mean==k ) return 1.0; + + double log_p = (k-mean)*log(p) + (mean-k)*log(1.0-p); + if ( k > N - k ) k = N - k; + if ( mean > N - mean ) mean = N - mean; + + if ( k < mean ) { int tmp = k; k = mean; mean = tmp; } + double diff = k - mean; + + double val = 1.0; + int i; + for (i=0; i10 && (1-q)*ndiploid>10 ) || ndiploid>200 ) + { + //fprintf(stderr,"out: mean=%e p=%e\n", mean,exp(-0.5*(nhets-mean)*(nhets-mean)/(mean*(1-q)))); + return exp(-0.5*(nhets-mean)*(nhets-mean)/(mean*(1-q))); + } + + return binom_dist(ndiploid, q, nhets); +} + +float calc_HOB(int nref, int nalt, int nhets, int ndiploid) +{ + if ( !nref || !nalt || !ndiploid ) return HUGE_VAL; + + double fref = (double)nref/(nref+nalt); // fraction of reference allelels + double falt = (double)nalt/(nref+nalt); // non-ref als + return fabs((double)nhets/ndiploid - 2*fref*falt); +} + +/** + * log(sum_i exp(a_i)) + */ +// static inline double logsumexp(double *vals, int nvals) +// { +// int i; +// double max_exp = vals[0]; +// for (i=1; ib ) + return log(1 + exp(b-a)) + a; + else + return log(1 + exp(a-b)) + b; +} + +// Macro to set the most likely alleles +#define UPDATE_MAX_LKs(als,sum) { \ + if ( max_lkhdr); + int ngts = nals*(nals+1)/2; + + // Single allele + for (ia=0; iapdg + iaa; + for (isample=0; isampletheta; // the prior + UPDATE_MAX_LKs(1<0 && lk_tot_set); + } + + // Two alleles + if ( nals>1 ) + { + for (ia=0; iaqsum[ia]==0 ) continue; + int iaa = (ia+1)*(ia+2)/2-1; + for (ib=0; ibqsum[ib]==0 ) continue; + double lk_tot = 0; + int lk_tot_set = 0; + double fa = call->qsum[ia]/(call->qsum[ia]+call->qsum[ib]); + double fb = call->qsum[ib]/(call->qsum[ia]+call->qsum[ib]); + double fa2 = fa*fa; + double fb2 = fb*fb; + double fab = 2*fa*fb; + int isample, ibb = (ib+1)*(ib+2)/2-1, iab = iaa - ia + ib; + double *pdg = call->pdg; + for (isample=0; isampleploidy || call->ploidy[isample]==2 ) + val = fa2*pdg[iaa] + fb2*pdg[ibb] + fab*pdg[iab]; + else if ( call->ploidy && call->ploidy[isample]==1 ) + val = fa*pdg[iaa] + fb*pdg[ibb]; + if ( val ) { lk_tot += log(val); lk_tot_set = 1; } + pdg += ngts; + } + if ( ia!=0 ) lk_tot += call->theta; // the prior + if ( ib!=0 ) lk_tot += call->theta; + UPDATE_MAX_LKs(1<2 ) + { + for (ia=0; iaqsum[ia]==0 ) continue; + int iaa = (ia+1)*(ia+2)/2-1; + for (ib=0; ibqsum[ib]==0 ) continue; + int ibb = (ib+1)*(ib+2)/2-1; + int iab = iaa - ia + ib; + for (ic=0; icqsum[ic]==0 ) continue; + double lk_tot = 0; + int lk_tot_set = 1; + double fa = call->qsum[ia]/(call->qsum[ia]+call->qsum[ib]+call->qsum[ic]); + double fb = call->qsum[ib]/(call->qsum[ia]+call->qsum[ib]+call->qsum[ic]); + double fc = call->qsum[ic]/(call->qsum[ia]+call->qsum[ib]+call->qsum[ic]); + double fa2 = fa*fa; + double fb2 = fb*fb; + double fc2 = fc*fc; + double fab = 2*fa*fb, fac = 2*fa*fc, fbc = 2*fb*fc; + int isample, icc = (ic+1)*(ic+2)/2-1; + int iac = iaa - ia + ic, ibc = ibb - ib + ic; + double *pdg = call->pdg; + for (isample=0; isampleploidy || call->ploidy[isample]==2 ) + val = fa2*pdg[iaa] + fb2*pdg[ibb] + fc2*pdg[icc] + fab*pdg[iab] + fac*pdg[iac] + fbc*pdg[ibc]; + else if ( call->ploidy && call->ploidy[isample]==1 ) + val = fa*pdg[iaa] + fb*pdg[ibb] + fc*pdg[icc]; + if ( val ) { lk_tot += log(val); lk_tot_set = 1; } + pdg += ngts; + } + if ( ia!=0 ) lk_tot += call->theta; // the prior + if ( ib!=0 ) lk_tot += call->theta; // the prior + if ( ic!=0 ) lk_tot += call->theta; // the prior + UPDATE_MAX_LKs(1<ref_lk = ref_lk; + call->lk_sum = lk_sum; + *out_als = max_als; + + int i, n = 0; + for (i=0; ihdr); + + for (i=0; iac[i] = 0; + call->nhets = 0; + call->ndiploid = 0; + + // Set all genotypes to 0/0 or 0 + int *gts = call->gts; + double *pdg = call->pdg; + int isample; + for (isample = 0; isample < nsmpl; isample++) + { + int ploidy = call->ploidy ? call->ploidy[isample] : 2; + for (i=0; iac[0] += ploidy; + } + gts += 2; + pdg += ngts; + } +} + +static void mcall_call_genotypes(call_t *call, bcf1_t *rec, int nals, int nout_als, int out_als) +{ + int ia, ib, i; + int ngts = nals*(nals+1)/2; + int nsmpl = bcf_hdr_nsamples(call->hdr); + int nout_gts = nout_als*(nout_als+1)/2; + hts_expand(float,nout_gts*nsmpl,call->nGPs,call->GPs); + + for (i=0; iac[i] = 0; + call->nhets = 0; + call->ndiploid = 0; + + #if USE_PRIOR_FOR_GTS + float prior = exp(call->theta); + #endif + float *gps = call->GPs - nout_gts; + double *pdg = call->pdg - ngts; + int *gts = call->gts - 2; + + int isample; + for (isample = 0; isample < nsmpl; isample++) + { + int ploidy = call->ploidy ? call->ploidy[isample] : 2; + assert( ploidy>=0 && ploidy<=2 ); + + pdg += ngts; + gts += 2; + gps += nout_gts; + + if ( !ploidy ) + { + gts[0] = bcf_gt_missing; + gts[1] = bcf_int32_vector_end; + gps[0] = -1; + continue; + } + + #if !FLAT_PDG_FOR_MISSING + // Skip samples with zero depth, they have all pdg's equal to 0 + for (i=0; indiploid++; + + // Default fallback for the case all LKs are the same + gts[0] = bcf_gt_unphased(0); + gts[1] = ploidy==2 ? bcf_gt_unphased(0) : bcf_int32_vector_end; + + // Non-zero depth, determine the most likely genotype + double best_lk = 0; + for (ia=0; iaqsum[ia]*call->qsum[ia] : pdg[iaa]*call->qsum[ia]; + #if USE_PRIOR_FOR_GTS + if ( ia!=0 ) lk *= prior; + #endif + int igt = ploidy==2 ? bcf_alleles2gt(call->als_map[ia],call->als_map[ia]) : call->als_map[ia]; + gps[igt] = lk; + if ( best_lk < lk ) + { + best_lk = lk; + gts[0] = bcf_gt_unphased(call->als_map[ia]); + } + } + if ( ploidy==2 ) + { + gts[1] = gts[0]; + for (ia=0; iaqsum[ia]*call->qsum[ib]; + #if USE_PRIOR_FOR_GTS + if ( ia!=0 ) lk *= prior; + if ( ib!=0 ) lk *= prior; + #endif + int igt = bcf_alleles2gt(call->als_map[ia],call->als_map[ib]); + gps[igt] = lk; + if ( best_lk < lk ) + { + best_lk = lk; + gts[0] = bcf_gt_unphased(call->als_map[ib]); + gts[1] = bcf_gt_unphased(call->als_map[ia]); + } + } + } + if ( gts[0] != gts[1] ) call->nhets++; + } + else + gts[1] = bcf_int32_vector_end; + + call->ac[ bcf_gt_allele(gts[0]) ]++; + if ( gts[1]!=bcf_int32_vector_end ) call->ac[ bcf_gt_allele(gts[1]) ]++; + } + if ( call->output_tags & (CALL_FMT_GQ|CALL_FMT_GP) ) + { + double max, sum; + for (isample=0; isampleGPs + isample*nout_gts; + + int nmax; + if ( call->ploidy ) + { + if ( call->ploidy[isample]==2 ) nmax = nout_gts; + else if ( call->ploidy[isample]==1 ) nmax = nout_als; + else nmax = 0; + } + else nmax = nout_gts; + + max = gps[0]; + if ( max<0 || nmax==0 ) + { + // no call + if ( call->output_tags & CALL_FMT_GP ) + { + for (i=0; iGQs[isample] = 0; + continue; + } + sum = gps[0]; + for (i=1; iGQs[isample] = max<=INT8_MAX ? max : INT8_MAX; + if ( call->output_tags & CALL_FMT_GP ) + { + assert( max ); + for (i=0; ioutput_tags & CALL_FMT_GP ) + bcf_update_format_float(call->hdr, rec, "GP", call->GPs, nsmpl*nout_gts); + if ( call->output_tags & CALL_FMT_GQ ) + bcf_update_format_int32(call->hdr, rec, "GQ", call->GQs, nsmpl); +} + + +/** + Pm = P(mendelian) .. parameter to vary, 1-Pm is the probability of novel mutation. + When trio_Pm_ins is negative, Pm is calculated dynamically + according to indel length. For simplicity, only the + first ALT is considered. + Pkij = P(k|i,j) .. probability that the genotype combination i,j,k is consistent + with mendelian inheritance (the likelihood that offspring + of two HETs is a HOM is smaller than it being a HET) + + P_uc(F=i,M=j,K=k) = P(F=i) . P(M=j) . P(K=k) .. unconstrained P + P_c(F=i,M=j,K=k) = P_uc . Pkij .. constrained P + P(F=i,M=j,K=k) = P_uc . (1 - Pm) + P_c . Pm + = P_uc . [1 - Pm + Pkij . Pm] + + We choose genotype combination i,j,k which maximizes P(F=i,M=j,K=k). This + probability gives the quality GQ(Trio). + Individual qualities are calculated as + GQ(F=i,M=j,K=k) = P(F=i,M=j,K=k) / \sum_{x,y} P(F=i,M=x,K=y) + */ +static void mcall_call_trio_genotypes(call_t *call, bcf1_t *rec, int nals, int nout_als, int out_als) +{ + int ia, ib, i; + int nsmpl = bcf_hdr_nsamples(call->hdr); + int ngts = nals*(nals+1)/2; + int nout_gts = nout_als*(nout_als+1)/2; + double *gls = call->GLs - nout_gts; + double *pdg = call->pdg - ngts; + + // Calculate individuals' genotype likelihoods P(X=i) + int isample; + for (isample = 0; isample < nsmpl; isample++) + { + int ploidy = call->ploidy ? call->ploidy[isample] : 2; + int32_t *gts = call->ugts + isample; + + gls += nout_gts; + pdg += ngts; + + // Skip samples with all pdg's equal to 1. These have zero depth. + for (i=0; ials_map[ia],call->als_map[ia]); + double lk = ploidy==2 ? pdg[iaa]*call->qsum[ia]*call->qsum[ia] : pdg[iaa]*call->qsum[ia]; + sum_lk += lk; + gls[idx] = lk; + if ( best_lk < lk ) + { + best_lk = lk; + gts[0] = bcf_alleles2gt(call->als_map[ia],call->als_map[ia]); + } + } + if ( ploidy==2 ) + { + for (ia=0; iaals_map[ia],call->als_map[ib]); + double lk = 2*pdg[iab]*call->qsum[ia]*call->qsum[ib]; + sum_lk += lk; + gls[idx] = lk; + if ( best_lk < lk ) + { + best_lk = lk; + gts[0] = bcf_alleles2gt(call->als_map[ib],call->als_map[ia]); + } + } + } + } + for (i=0; itrio_Pm_ins<0 && call->trio_Pm_del<0 ) trio_Pm = call->trio_Pm_SNPs; // the same Pm for indels and SNPs requested + else + { + int ret = bcf_get_variant_types(rec); + if ( !(ret & VCF_INDEL) ) trio_Pm = call->trio_Pm_SNPs; + else + { + if ( call->trio_Pm_ins<0 ) // dynamic calculation, trio_Pm_del holds the scaling factor + { + trio_Pm = rec->d.var[1].n<0 ? -21.9313 - 0.2856*rec->d.var[1].n : -22.8689 + 0.2994*rec->d.var[1].n; + trio_Pm = 1 - call->trio_Pm_del * exp(trio_Pm); + } + else // snps and indels set explicitly + { + trio_Pm = rec->d.var[1].n<0 ? call->trio_Pm_del : call->trio_Pm_ins; + } + } + } + + // Calculate constrained likelihoods and determine genotypes + int ifm; + for (ifm=0; ifmnfams; ifm++) + { + family_t *fam = &call->fams[ifm]; + int ntrio = call->ntrio[fam->type][nout_als]; + uint16_t *trio = call->trio[fam->type][nout_als]; + + // Unconstrained likelihood + int uc_itr = 0; + double uc_lk = 0; + for (i=0; i<3; i++) // for father, mother, child + { + int ismpl = fam->sample[i]; + double *gl = call->GLs + nout_gts*ismpl; + if ( gl[0]==1 ) continue; + int j, jmax = 0; + double max = gl[0]; + for (j=1; jsample[i]; + double *gl = call->GLs + nout_gts*ismpl; + if ( gl[0]==1 ) continue; + int igt = trio[itr]>>((2-i)*4) & 0xf; + assert( !call->ploidy || call->ploidy[ismpl]>0 ); + if ( igt==GT_SKIP ) continue; + lk += gl[igt]; + npresent++; + // fprintf(stderr," %e", gl[igt]); + } + // fprintf(stderr,"\t\t"); + double Pkij = npresent==3 ? (double)2/(trio[itr]>>12) : 1; // with missing genotypes Pkij's are different + lk += log(1 - trio_Pm * (1 - Pkij)); + // fprintf(stderr,"%d%d%d\t%e\t%.2f\n", trio[itr]>>8&0xf,trio[itr]>>4&0xf,trio[itr]&0xf, lk, Pkij); + if ( c_lk < lk ) { c_lk = lk; c_itr = trio[itr]; } + if ( uc_itr==trio[itr] ) uc_is_mendelian = 1; + } + + if ( !uc_is_mendelian ) + { + uc_lk += log(1 - trio_Pm); + // fprintf(stderr,"c_lk=%e uc_lk=%e c_itr=%d%d%d uc_itr=%d%d%d\n", c_lk,uc_lk,c_itr>>8&0xf,c_itr>>4&0xf,c_itr&0xf,uc_itr>>8&0xf,uc_itr>>4&0xf,uc_itr&0xf); + if ( c_lk < uc_lk ) { c_lk = uc_lk; c_itr = uc_itr; } + } + // fprintf(stderr,"best_lk=%e best_itr=%d%d%d uc_itr=%d%d%d\n", c_lk,c_itr>>8&0xf,c_itr>>4&0xf,c_itr&0xf,uc_itr>>8&0xf,uc_itr>>4&0xf,uc_itr&0xf); + + // Set genotypes for father, mother, child and calculate genotype qualities + for (i=0; i<3; i++) + { + // GT + int ismpl = fam->sample[i]; + int igt = c_itr>>((2-i)*4) & 0xf; + double *gl = call->GLs + nout_gts*ismpl; + int32_t *gts = call->cgts + ismpl; + if ( gl[0]==1 || igt==GT_SKIP ) // zero depth, set missing genotypes + { + gts[0] = -1; + // bcf_float_set_missing(call->GQs[ismpl]); + continue; + } + gts[0] = igt; + + #if 0 + // todo: Genotype Qualities + // + // GQ: for each family member i sum over all genotypes j,k keeping igt fixed + double lk_sum = 0; + for (itr=0; itr>((2-i)*4) & 0xf) ) continue; + double lk = 0; + int j; + for (j=0; j<3; j++) + { + int jsmpl = fam->sample[j]; + double *gl = call->GLs + ngts*jsmpl; + if ( gl[0]==1 ) continue; + int jgt = trio[itr]>>((2-j)*4) & 0xf; + if ( jgt==GT_SKIP ) continue; + lk += gl[jgt]; + } + double Pkij = (double)2/(trio[itr]>>12); + lk += log(1 - trio_Pm * (1 - Pkij)); + lk_sum = logsumexp2(lk_sum, lk); + } + if ( !uc_is_mendelian && (best_itr>>((2-i)*4)&0xf)==(uc_itr>>((2-i)*4)&0xf) ) lk_sum = logsumexp2(lk_sum,uc_lk); + call->GQs[ismpl] = -4.3429*(best_lk - lk_sum); + #endif + } + } + + for (i=0; i<4; i++) call->ac[i] = 0; + call->nhets = 0; + call->ndiploid = 0; + + // Test if CGT,UGT are needed + int ucgts_needed = 0; + int32_t *cgts = call->cgts - 1; + int32_t *ugts = call->ugts - 1; + int32_t *gts = call->gts - 2; + for (isample = 0; isample < nsmpl; isample++) + { + int ploidy = call->ploidy ? call->ploidy[isample] : 2; + cgts++; + ugts++; + gts += 2; + if ( ugts[0]==-1 ) + { + gts[0] = bcf_gt_missing; + gts[1] = ploidy==2 ? bcf_gt_missing : bcf_int32_vector_end; + continue; + } + int a,b; + if ( cgts[0]!=ugts[0] ) + { + bcf_gt2alleles(cgts[0], &a, &b); + gts[0] = bcf_gt_unphased(a); + gts[1] = ploidy==1 ? bcf_int32_vector_end : bcf_gt_unphased(b); + } + else + { + bcf_gt2alleles(ugts[0], &a, &b); + gts[0] = bcf_gt_unphased(a); + gts[1] = ploidy==1 ? bcf_int32_vector_end : bcf_gt_unphased(b); + } + if ( cgts[0]!=ugts[0] ) ucgts_needed = 1; + call->ac[a]++; + if ( ploidy==2 ) + { + call->ac[b]++; + call->ndiploid++; + if ( a!=b ) call->nhets++; + } + } + if ( ucgts_needed ) + { + // Some GTs are different + bcf_update_format_int32(call->hdr,rec,"UGT",call->ugts,nsmpl); + bcf_update_format_int32(call->hdr,rec,"CGT",call->cgts,nsmpl); + } +} + +static void mcall_trim_PLs(call_t *call, bcf1_t *rec, int nals, int nout_als, int out_als) +{ + int ngts = nals*(nals+1)/2; + int npls_src = ngts, npls_dst = nout_als*(nout_als+1)/2; // number of PL values in diploid samples, ori and new + if ( call->all_diploid && npls_src == npls_dst ) return; + + int *pls_src = call->PLs, *pls_dst = call->PLs; + + int nsmpl = bcf_hdr_nsamples(call->hdr); + int isample, ia; + for (isample = 0; isample < nsmpl; isample++) + { + int ploidy = call->ploidy ? call->ploidy[isample] : 2; + if ( ploidy==2 ) + { + for (ia=0; iapl_map[ia] ]; + } + else if ( ploidy==1 ) + { + for (ia=0; iapl_map[isrc] ]; + } + if ( ia1 in mcall() + } + pls_src += npls_src; + pls_dst += npls_dst; + } + bcf_update_format_int32(call->hdr, rec, "PL", call->PLs, npls_dst*nsmpl); +} + +void mcall_trim_numberR(call_t *call, bcf1_t *rec, int nals, int nout_als, int out_als) +{ + if ( nals==nout_als ) return; + + int i,j, nret, size = sizeof(float); + + void *tmp_ori = call->itmp, *tmp_new = call->PLs; // reusing PLs storage which is not used at this point + int ntmp_ori = call->n_itmp, ntmp_new = call->mPLs; + + // INFO fields + for (i=0; in_info; i++) + { + bcf_info_t *info = &rec->d.info[i]; + int vlen = bcf_hdr_id2length(call->hdr,BCF_HL_INFO,info->key); + if ( vlen!=BCF_VL_R ) continue; // not a Number=R tag + + int type = bcf_hdr_id2type(call->hdr,BCF_HL_INFO,info->key); + const char *key = bcf_hdr_int2id(call->hdr,BCF_DT_ID,info->key); + nret = bcf_get_info_values(call->hdr, rec, key, &tmp_ori, &ntmp_ori, type); + if ( nret<=0 ) continue; + + if ( nout_als==1 ) + bcf_update_info_int32(call->hdr, rec, key, tmp_ori, 1); // has to be the REF, the order could not change + else + { + for (j=0; jals_map[j]; + if ( k==-1 ) continue; // to be dropped + memcpy((char *)tmp_new+size*k, (char *)tmp_ori+size*j, size); + } + bcf_update_info_int32(call->hdr, rec, key, tmp_new, nout_als); + } + } + + // FORMAT fields + for (i=0; in_fmt; i++) + { + bcf_fmt_t *fmt = &rec->d.fmt[i]; + int vlen = bcf_hdr_id2length(call->hdr,BCF_HL_FMT,fmt->id); + if ( vlen!=BCF_VL_R ) continue; // not a Number=R tag + + int type = bcf_hdr_id2type(call->hdr,BCF_HL_FMT,fmt->id); + const char *key = bcf_hdr_int2id(call->hdr,BCF_DT_ID,fmt->id); + nret = bcf_get_format_values(call->hdr, rec, key, &tmp_ori, &ntmp_ori, type); + if (nret<=0) continue; + int nsmpl = bcf_hdr_nsamples(call->hdr); + + assert( nret==nals*nsmpl ); + + for (j=0; jals_map[k]; + if ( l==-1 ) continue; // to be dropped + memcpy(ptr_dst+size*l, ptr_src+size*k, size); + } + } + bcf_update_format_int32(call->hdr, rec, key, tmp_new, nout_als*nsmpl); + } + + call->PLs = (int32_t*) tmp_new; + call->mPLs = ntmp_new; + call->itmp = (int32_t*) tmp_ori; + call->n_itmp = ntmp_ori; +} + + +// NB: in this function we temporarily use calls->als_map for a different +// purpose to store mapping from new (target) alleles to original alleles. +// +static int mcall_constrain_alleles(call_t *call, bcf1_t *rec, int *unseen) +{ + bcf_sr_regions_t *tgt = call->srs->targets; + if ( tgt->nals>5 ) error("Maximum accepted number of alleles is 5, got %d\n", tgt->nals); + hts_expand(char*,tgt->nals+1,call->nals,call->als); + + int has_new = 0; + + int i, j, nals = 1; + for (i=1; inals_map; i++) call->als_map[i] = -1; + + if ( vcmp_set_ref(call->vcmp, rec->d.allele[0], tgt->als[0]) < 0 ) + error("The reference alleles are not compatible at %s:%d .. %s vs %s\n", call->hdr->id[BCF_DT_CTG][rec->rid].key,rec->pos+1,tgt->als[0],rec->d.allele[0]); + + // create mapping from new to old alleles + call->als[0] = tgt->als[0]; + call->als_map[0] = 0; + + for (i=1; inals; i++) + { + call->als[nals] = tgt->als[i]; + j = vcmp_find_allele(call->vcmp, rec->d.allele+1, rec->n_allele - 1, tgt->als[i]); + + if ( j+1==*unseen ) { fprintf(stderr,"fixme? Cannot constrain to %s\n",tgt->als[i]); return -1; } + + if ( j>=0 ) + { + // existing allele + call->als_map[nals] = j+1; + } + else + { + // There is a new allele in targets which is not present in VCF. + // We use the X allele to estimate PLs. Note that X may not be + // present at multiallelic indels sites. In that case we use the + // last allele anyway, because the least likely allele comes last + // in mpileup's ALT output. + call->als_map[nals] = (*unseen)>=0 ? *unseen : rec->n_allele - 1; + has_new = 1; + } + nals++; + } + if ( *unseen ) + { + call->als_map[nals] = *unseen; + call->als[nals] = rec->d.allele[*unseen]; + nals++; + } + + if ( !has_new && nals==rec->n_allele ) return 0; + bcf_update_alleles(call->hdr, rec, (const char**)call->als, nals); + + // create mapping from new PL to old PL + int k = 0; + for (i=0; ials_map[i], b = call->als_map[j]; + call->pl_map[k++] = a>b ? a*(a+1)/2 + b : b*(b+1)/2 + a; + } + } + + // update PL + call->nPLs = bcf_get_format_int32(call->hdr, rec, "PL", &call->PLs, &call->mPLs); + int nsmpl = bcf_hdr_nsamples(call->hdr); + int npls_ori = call->nPLs / nsmpl; + int npls_new = k; + hts_expand(int32_t,npls_new*nsmpl,call->n_itmp,call->itmp); + int *ori_pl = call->PLs, *new_pl = call->itmp; + for (i=0; ipl_map[k]]; + if ( new_pl[k]==bcf_int32_missing && *unseen>=0 ) + { + // missing value, and there is an unseen allele: identify the + // alleles and use the lk of either AX or XX + int k_ori = call->pl_map[k], ia, ib; + bcf_gt2alleles(k_ori, &ia, &ib); + k_ori = bcf_alleles2gt(ia,*unseen); + if ( ori_pl[k_ori]==bcf_int32_missing ) k_ori = bcf_alleles2gt(ib,*unseen); + if ( ori_pl[k_ori]==bcf_int32_missing ) k_ori = bcf_alleles2gt(*unseen,*unseen); + new_pl[k] = ori_pl[k_ori]; + } + if ( !k && new_pl[k]==bcf_int32_vector_end ) new_pl[k]=bcf_int32_missing; + } + ori_pl += npls_ori; + new_pl += npls_new; + } + bcf_update_format_int32(call->hdr, rec, "PL", call->itmp, npls_new*nsmpl); + + // update QS + float qsum[5]; + int nqs = bcf_get_info_float(call->hdr, rec, "QS", &call->qsum, &call->nqsum); + for (i=0; ials_map[i]qsum[call->als_map[i]] : 0; + bcf_update_info_float(call->hdr, rec, "QS", qsum, nals); + + if ( *unseen ) *unseen = nals-1; + return 0; +} + + +/** + * This function implements the multiallelic calling model. It has two major parts: + * 1) determine the most likely set of alleles and calculate the quality of ref/non-ref site + * 2) determine and set the genotypes + * In various places in between, the BCF record gets updated. + */ +int mcall(call_t *call, bcf1_t *rec) +{ + int i, unseen = call->unseen; + + // Force alleles when calling genotypes given alleles was requested + if ( call->flag & CALL_CONSTR_ALLELES && mcall_constrain_alleles(call, rec, &unseen)!=0 ) return -2; + + int nsmpl = bcf_hdr_nsamples(call->hdr); + int nals = rec->n_allele; + hts_expand(int,nals,call->nac,call->ac); + hts_expand(int,nals,call->nals_map,call->als_map); + hts_expand(int,nals*(nals+1)/2,call->npl_map,call->pl_map); + + // Get the genotype likelihoods + call->nPLs = bcf_get_format_int32(call->hdr, rec, "PL", &call->PLs, &call->mPLs); + if ( call->nPLs!=nsmpl*nals*(nals+1)/2 && call->nPLs!=nsmpl*nals ) // a mixture of diploid and haploid or haploid only + error("Wrong number of PL fields? nals=%d npl=%d\n", nals,call->nPLs); + + // Convert PLs to probabilities + int ngts = nals*(nals+1)/2; + hts_expand(double, call->nPLs, call->npdg, call->pdg); + set_pdg(call->pl2p, call->PLs, call->pdg, nsmpl, ngts, unseen); + + #if QS_FROM_PDG + estimate_qsum(call, rec); + #else + // Get sum of qualities, serves as an AF estimate, f_x = QS/N in Eq. 1 in call-m math notes. + int nqs = bcf_get_info_float(call->hdr, rec, "QS", &call->qsum, &call->nqsum); + if ( nqs<=0 ) error("The QS annotation not present at %s:%d\n", bcf_seqname(call->hdr,rec),rec->pos+1); + if ( nqs < nals ) + { + // Some of the listed alleles do not have the corresponding QS field. This is + // typically ref-only site with X in ALT. + + hts_expand(float,nals,call->nqsum,call->qsum); + for (i=nqs; iqsum[i] = 0; + } + + // If available, take into account reference panel AFs + if ( call->prior_AN && bcf_get_info_int32(call->hdr, rec, call->prior_AN ,&call->ac, &call->nac)==1 ) + { + int an = call->ac[0]; + if ( bcf_get_info_int32(call->hdr, rec, call->prior_AC ,&call->ac, &call->nac)==nals-1 ) + { + int ac0 = an; // number of alleles in the reference population + for (i=0; iac[i]==bcf_int32_vector_end ) break; + if ( call->ac[i]==bcf_int32_missing ) continue; + ac0 -= call->ac[i]; + call->qsum[i+1] += call->ac[i]*0.5; + } + if ( ac0<0 ) error("Incorrect %s,%s values at %s:%d\n", call->prior_AN,call->prior_AC,bcf_seqname(call->hdr,rec),rec->pos+1); + call->qsum[0] += ac0*0.5; + for (i=0; iqsum[i] /= nsmpl + 0.5*an; + } + } + + float qsum_tot = 0; + for (i=0; iqsum[i]; + + // Is this still necessary?? + // + // if (0&& !call->qsum[0] ) + // { + // // As P(RR)!=0 even for QS(ref)=0, we set QS(ref) to a small value, + // // an equivalent of a single reference read. + // if ( bcf_get_info_int32(call->hdr, rec, "DP", &call->itmp, &call->n_itmp)!=1 ) + // error("Could not read DP at %s:%d\n", call->hdr->id[BCF_DT_CTG][rec->rid].key,rec->pos+1); + // if ( call->itmp[0] ) + // { + // call->qsum[0] = 1.0 / call->itmp[0] / nsmpl; + // qsum_tot += call->qsum[0]; + // } + // } + + if ( qsum_tot ) for (i=0; iqsum[i] /= qsum_tot; + #endif + + bcf_update_info_int32(call->hdr, rec, "QS", NULL, 0); // remove QS tag + + // Find the best combination of alleles + int out_als, nout; + if ( nals > 8*sizeof(out_als) ) + { + fprintf(stderr,"Too many alleles at %s:%d, skipping.\n", bcf_seqname(call->hdr,rec),rec->pos+1); + return 0; + } + nout = mcall_find_best_alleles(call, nals, &out_als); + + // Make sure the REF allele is always present + if ( !(out_als&1) ) + { + out_als |= 1; + nout++; + } + int is_variant = out_als==1 ? 0 : 1; + if ( call->flag & CALL_VARONLY && !is_variant ) return 0; + + // With -A, keep all ALTs except X + if ( call->flag & CALL_KEEPALT ) + { + nout = 0; + for (i=0; i0 && i==unseen ) continue; + out_als |= 1<hdr, rec, "PL", NULL, 0); // remove PL, useless now + } + else + { + // The most likely set of alleles includes non-reference allele (or was enforced), call genotypes. + // Note that it is a valid outcome if the called genotypes exclude some of the ALTs. + init_allele_trimming_maps(call, out_als, nals); + if ( !is_variant ) + mcall_set_ref_genotypes(call,nals); // running with -A, prevent mcall_call_genotypes from putting some ALT back + else if ( call->flag & CALL_CONSTR_TRIO ) + { + if ( nout>4 ) + { + fprintf(stderr,"Too many alleles at %s:%d, skipping.\n", bcf_seqname(call->hdr,rec),rec->pos+1); + return 0; + } + mcall_call_trio_genotypes(call, rec, nals,nout,out_als); + } + else + mcall_call_genotypes(call,rec,nals,nout,out_als); + + // Skip the site if all samples are 0/0. This can happen occasionally. + nAC = 0; + for (i=1; iac[i]; + if ( !nAC && call->flag & CALL_VARONLY ) return 0; + mcall_trim_PLs(call, rec, nals, nout, out_als); + } + if ( nals!=nout ) mcall_trim_numberR(call, rec, nals, nout, out_als); + + // Set QUAL and calculate HWE-related annotations + if ( nAC ) + { + float icb = calc_ICB(call->ac[0],nAC, call->nhets, call->ndiploid); + if ( icb != HUGE_VAL ) bcf_update_info_float(call->hdr, rec, "ICB", &icb, 1); + + float hob = calc_HOB(call->ac[0],nAC, call->nhets, call->ndiploid); + if ( hob != HUGE_VAL ) bcf_update_info_float(call->hdr, rec, "HOB", &hob, 1); + + // Quality of a variant site. fabs() to avoid negative zeros in VCF output when CALL_KEEPALT is set + rec->qual = -4.343*(call->ref_lk - logsumexp2(call->lk_sum,call->ref_lk)); + } + else + { + // Set the quality of a REF site + if ( call->lk_sum==-HUGE_VAL ) // no support from (high quality) reads, so QUAL=1-prior + rec->qual = call->theta ? -4.343*call->theta : 0; + else + rec->qual = -4.343*(call->lk_sum - logsumexp2(call->lk_sum,call->ref_lk)); + } + + if ( rec->qual>999 ) rec->qual = 999; + if ( rec->qual>50 ) rec->qual = rint(rec->qual); + + // AC, AN + if ( nout>1 ) bcf_update_info_int32(call->hdr, rec, "AC", call->ac+1, nout-1); + nAC += call->ac[0]; + bcf_update_info_int32(call->hdr, rec, "AN", &nAC, 1); + + // Remove unused alleles + hts_expand(char*,nout,call->nals,call->als); + for (i=0; ials_map[i]>=0 ) call->als[call->als_map[i]] = rec->d.allele[i]; + bcf_update_alleles(call->hdr, rec, (const char**)call->als, nout); + bcf_update_genotypes(call->hdr, rec, call->gts, nsmpl*2); + + // DP4 tag + if ( bcf_get_info_float(call->hdr, rec, "I16", &call->anno16, &call->n16)==16 ) + { + int32_t dp[4]; dp[0] = call->anno16[0]; dp[1] = call->anno16[1]; dp[2] = call->anno16[2]; dp[3] = call->anno16[3]; + bcf_update_info_int32(call->hdr, rec, "DP4", dp, 4); + + int32_t mq = (call->anno16[8]+call->anno16[10])/(call->anno16[0]+call->anno16[1]+call->anno16[2]+call->anno16[3]); + bcf_update_info_int32(call->hdr, rec, "MQ", &mq, 1); + } + + bcf_update_info_int32(call->hdr, rec, "I16", NULL, 0); // remove I16 tag + + return nout; +} + diff --git a/misc/color-chrs.pl b/misc/color-chrs.pl new file mode 100755 index 0000000..4afb9c7 --- /dev/null +++ b/misc/color-chrs.pl @@ -0,0 +1,528 @@ +#!/usr/bin/env perl +# +# Copyright (C) 2015 Genome Research Ltd. +# +# Author: Petr Danecek +# +# Permission is hereby granted, free of charge, to any person obtaining a copy +# of this software and associated documentation files (the "Software"), to deal +# in the Software without restriction, including without limitation the rights +# to use, copy, modify, merge, publish, distribute, sublicense, and/or sell +# copies of the Software, and to permit persons to whom the Software is +# furnished to do so, subject to the following conditions: +# +# The above copyright notice and this permission notice shall be included in +# all copies or substantial portions of the Software. +# +# THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +# IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +# FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL +# THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER +# LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING +# FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER +# DEALINGS IN THE SOFTWARE. + +use strict; +use warnings; +use Carp; + +my $opts = parse_params(); +chr_dims($opts); +for my $file (@{$$opts{files}}) +{ + read_dat($opts,$file); +} +merge_regs($opts); +plot($opts); + +exit; + +#-------------------------------- + +sub error +{ + my (@msg) = @_; + if ( scalar @msg ) { confess @msg; } + print + "About: Plot output of \"bcftools +color-chrs\"\n", + "Usage: color-chrs.pl [OPTIONS] output.dat\n", + "Options:\n", + " -c, --colors File with list of \"chr hap color\".\n", + " -p, --prefix Prefix of output files.\n", + " -h, -?, --help This help message.\n", + "\n"; + exit -1; +} + +sub parse_params +{ + my $opts = + { + #colors => ['red','green','blue','yellow'], + colors => ['#ff0000','#008000','#0000ff','#ffff00'], + height => 350, + pad => 10, + dimL => 300, # arm length + dimD => 10, # arm width + dimE => 7, # arm pad + dimB => 5, # arm end curve + }; + $$opts{chr_width} = 2*$$opts{pad} + 2*$$opts{dimD} + $$opts{dimE}; + $$opts{width} = $$opts{chr_width}*23; + while (defined(my $arg=shift(@ARGV))) + { + if ( -e $arg ) { push @{$$opts{files}},$arg; next } + if ( $arg eq '-p' || $arg eq '--prefix' ) { $$opts{prefix}=shift(@ARGV); next } + if ( $arg eq '-c' || $arg eq '--colors' ) { read_colors($opts,shift(@ARGV)); next; } + if ( $arg eq '-?' || $arg eq '-h' || $arg eq '--help' ) { error(); } + error("Unknown parameter \"$arg\". Run -h for help.\n"); + } + if ( !exists($$opts{files}) ) { error("No files given?\n") } + if ( !exists($$opts{prefix}) ) { error("Expected -p option\n") } + return $opts; +} + +sub read_colors +{ + my ($opts,$fname) = @_; + open(my $fh,'<',$fname) or error("$fname: $!"); + while (my $line=<$fh>) + { + if ( $line=~/^\s*$/ ) { next; } + $line =~ s/^\s*//; + $line =~ s/\s*$//; + my ($chr,$hap,$col) = split(/\s+/,$line); + $$opts{hap_cols}{$chr}{$hap} = $col; + } + close($fh); +} + +sub plot +{ + my ($opts) = @_; + + my $width = $$opts{width}; + my $height = $$opts{height}; + my $pad = $$opts{pad}; + + my $svg = $$opts{svg} = []; + push @$svg, q[]; + push @$svg, q[]; + push @$svg, qq[]; + + my $xpos = $pad; + for my $chr (qw(1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 X)) + { + draw_chr($opts,$chr,$xpos,$pad); + $xpos += $$opts{chr_width}; + } + $xpos = $pad + 10*$$opts{chr_width}; + for my $sample (keys %{$$opts{samples}}) + { + $$opts{chrs}{$sample} = { len=>59e6, acen=>[24e6,26e6,28e6] }; + my $chr = $$opts{chrs}{$sample}; + my $len1 = $$opts{dimL}*$$chr{acen}[0]/$$opts{max_chr_len}; + my $len2 = $$opts{dimL}*$$chr{acen}[2]/$$opts{max_chr_len}; + my $len3 = $$opts{dimL}*$$chr{len}/$$opts{max_chr_len}; + if ( exists($$opts{samples}{$sample}{1}) ) + { + my $col = $$opts{samples}{$sample}{1}; + $$chr{px1} = [[0,$len1,{$col=>1.0}],[$len2,$len3,{$col=>1.0}]]; + } + if ( exists($$opts{samples}{$sample}{2}) ) + { + my $col = $$opts{samples}{$sample}{2}; + $$chr{px2} = [[0,$len1,{$col=>1.0}],[$len2,$len3,{$col=>1.0}]]; + } + my $ypos = $$opts{dimL} - $len3 + $pad; + draw_chr($opts,$sample,$xpos,$ypos); + $xpos += 2*$$opts{chr_width}; + } + + push @$svg, q[]; + open(my $fh,'>',"$$opts{prefix}.svg"); + print $fh join("\n",@$svg); + close($fh); +} + +sub draw_chr +{ + my ($opts,$chr_name,$xpos,$ypos) = @_; + + my $svg = $$opts{svg}; + my $chr = $$opts{chrs}{$chr_name}; + my $dimL = $$opts{dimL}; + my $dimC = $dimL*($$chr{acen}[2]-$$chr{acen}[0])/$$opts{max_chr_len}; + my $dimL1 = $dimL*$$chr{acen}[0]/$$opts{max_chr_len}; + my $dimL2 = $dimL*($$chr{len} - $$chr{acen}[2])/$$opts{max_chr_len}; + my $dimD = $$opts{dimD}; # arm width + my $dimB = $$opts{dimB}; + my $dimE = $$opts{dimE}; # the gap width between arms + my $dimE05 = $dimE*0.5; + my $dimD05 = $dimD*0.5; + my $dimB05 = $dimB*0.5; + my $dimC05 = 0.5*$dimC; + + my $xtext = $xpos + $dimD + $dimE*0.5; + my $ytext = $ypos; + push @$svg, qq[$chr_name\n]; + + $ypos += $$opts{pad}; + + push @$svg, qq[ + ]; + + if ( $$chr{px1} ) { draw_regs($opts,$chr_name,$$chr{px1},$xpos,$ypos); } + if ( $$chr{px2} ) { draw_regs($opts,$chr_name,$$chr{px2},$xpos+$dimD+$dimE,$ypos); } +} + +sub parse_hex_color +{ + my ($color) = @_; + if ( !($color=~/^#/) ) { error("Could not parse: $color"); } + $color =~ s/^#//; + my @vals = split(//, $color); + my ($r,$g,$b); + if ( @vals==6 ) + { + $r = hex($vals[0].$vals[1]); + $g = hex($vals[2].$vals[3]); + $b = hex($vals[4].$vals[5]); + } + elsif ( @vals==3 ) + { + $r = hex($vals[0].$vals[0]); + $g = hex($vals[1].$vals[1]); + $b = hex($vals[2].$vals[2]); + } + else { error("Could not parse: $color\n"); } + return ($r,$g,$b); +} + +sub scale_color +{ + my ($color,$scale) = @_; + my ($r1,$g1,$b1) = parse_hex_color($color); + my ($r0,$g0,$b0) = parse_hex_color('#aaa'); + my $r = $scale*($r1-$r0) + $r0; + my $g = $scale*($g1-$g0) + $g0; + my $b = $scale*($b1-$b0) + $b0; + return sprintf("#%0.2x%0.2x%0.2x",$r,$g,$b); +} + +sub draw_regs +{ + my ($opts,$chr_name,$regs,$xpos,$ypos) = @_; + + my $svg = $$opts{svg}; + my $chr = $$opts{chrs}{$chr_name}; + my $dimL = $$opts{dimL}; + my $dimC = $dimL*($$chr{acen}[2]-$$chr{acen}[0])/$$opts{max_chr_len}; + my $dimL1 = $dimL*$$chr{acen}[0]/$$opts{max_chr_len}; + my $dimL2 = $$opts{dimL} - $dimL*$$chr{acen}[2]/$$opts{max_chr_len}; + my $dimD = $$opts{dimD}; # arm width + my $dimB = $$opts{dimB}; + my $dimE = $$opts{dimE}; + my $dimE05 = $dimE*0.5; + my $dimD05 = $dimD*0.5; + my $dimB05 = $dimB*0.5; + my $dimC05 = 0.5*$dimC; + + for my $reg (@$regs) + { + my $sum = 0; + my $cmax = undef; + for my $c (keys %{$$reg[2]}) + { + $sum += $$reg[2]{$c}; + if ( !defined $cmax or $$reg[2]{$cmax} < $$reg[2]{$c} ) { $cmax = $c; } + } + my $color = scale_color($cmax,$$reg[2]{$cmax}/$sum); + my $y = $ypos + $$reg[0]; + my $dy = $$reg[1] - $$reg[0] + 1; + push @$svg, qq[ + ]; + } + +} + +sub hap2color +{ + my ($opts,$chr,$hap) = @_; + if ( exists($$opts{hap_cols}{$chr}{$hap}) ) + { + if ( !exists($$opts{hap_cols}{'*'}{$hap}) ) + { + $$opts{hap_cols}{'*'}{$hap} = $$opts{hap_cols}{$chr}{$hap}; + } + return $$opts{hap_cols}{$chr}{$hap}; + } + elsif ( exists($$opts{hap_cols}{'*'}{$hap}) ) + { + return $$opts{hap_cols}{'*'}{$hap}; + } + if ( !exists($$opts{haps}) ) { $$opts{haps} = {}; } + if ( !exists($$opts{haps}{$hap}) ) + { + my $nhaps = scalar keys %{$$opts{haps}}; + my $color = $$opts{colors}[$nhaps]; + $$opts{haps}{$hap} = $color; + } + return $$opts{haps}{$hap}; +} + +sub read_dat +{ + my ($opts,$file) = @_; + open(my $fh,'<',$file) or error("$file: $!"); + while (my $line=<$fh>) + { + if ( !($line=~/^SG/) ) { next; } + my @items = split(/\s+/,$line); + my $chr = $items[1]; + my $start = $items[2]; + my $end = $items[3]; + my $hap1 = $items[4]; + my $hap2 = $items[5]; + my $col1 = hap2color($opts,$chr,$hap1); + my $col2 = hap2color($opts,$chr,$hap2); + push @{$$opts{chrs}{$chr}{regs1}},[$start,$end,$col1]; + push @{$$opts{chrs}{$chr}{regs2}},[$start,$end,$col2]; + my ($smpl,$hap); + ($smpl,$hap) = split(/:/,$hap1); $$opts{samples}{$smpl}{$hap} = $col1; + ($smpl,$hap) = split(/:/,$hap2); $$opts{samples}{$smpl}{$hap} = $col2; + } + close($fh); +} + +sub merge_regs +{ + my ($opts) = @_; + for my $chr (keys %{$$opts{chrs}}) + { + my $dat = $$opts{chrs}{$chr}; + if ( exists($$dat{regs1}) ) { $$dat{px1} = merge($opts,$dat,$$dat{regs1}); } + if ( exists($$dat{regs2}) ) { $$dat{px2} = merge($opts,$dat,$$dat{regs2}); } + } +} + +sub merge +{ + my ($opts,$chr_dat,$regs) = @_; + + # merge adjacent regions of the same color + for (my $i=1; $i<@$regs; $i++) + { + if ( $$regs[$i-1][2] eq $$regs[$i][2] ) + { + $$regs[$i-1][1] = $$regs[$i][1]; + splice(@$regs,$i,1); + $i--; + next; + } + } + for (my $i=0; $i<@$regs; $i++) + { + if ( $$regs[$i][1] < $$chr_dat{acen}[0] ) { next; } + if ( $$regs[$i][0] > $$chr_dat{acen}[2] ) { next; } + if ( $$regs[$i][0] >= $$chr_dat{acen}[0] && $$regs[$i][1] <= $$chr_dat{acen}[2] ) + { + splice(@$regs,$i,1); + $i--; + next; + } + if ( $$regs[$i][1] < $$chr_dat{acen}[2] ) + { + $$regs[$i][1] = $$chr_dat{acen}[0]; + next; + } + if ( $$regs[$i][0] > $$chr_dat{acen}[0] ) + { + $$regs[$i][0] = $$chr_dat{acen}[2]; + next; + } + my $start = $$chr_dat{acen}[2]; + my $end = $$regs[$i][1]; + my $color = $$regs[$i][2]; + $$regs[$i][1] = $$chr_dat{acen}[0]; + splice(@$regs,$i+1,0,[$start,$end,$color]); + } + + # pixelize + my @px = ([0,0,{}]); # start,end,hash of contributions from colors + my $dy = $$opts{max_chr_len}/$$opts{dimL}; # 1px covers $dy base pairs + for my $reg (@$regs) + { + my $px_start = int($$reg[0] / $dy); + my $px_end = int($$reg[1] / $dy); + my $color = $$reg[2]; + my $contrib = ($$reg[1] - $$reg[0])/$dy; + + if ( $px_start==$px_end ) + { + if ( $px_end<=$px[-1][1] ) { $px[-1][2]{$color} += $contrib; } + else { push @px, [$px_start,$px_end,{$color=>$contrib}]; } + next; + } + + my $rem_start = 1 - ($$reg[0]/$dy - $px_start); # fractional remainders + my $rem_end = $$reg[1]/$dy - $px_end; + + if ( $px_start==$px[-1][1] ) + { + $px[-1][2]{$color} += $rem_start; + } + + if ( $px_end==$px[-1][1] ) + { + $px[-1][2]{$color} += $rem_end; + if ( $px_start+1<$px_end ) { error("really?!\n"); } + } + elsif ( $px_end>$px[-1][1] ) + { + if ( $rem_start ) { $px_start++; $contrib -= $rem_start; } + push @px, [ $px_start, $px_end, { $color=>$contrib } ]; + } + else { error("really?!\n"); } + } + return \@px; +} + +sub chr_dims +{ + my ($opts) = @_; + + # http://hgdownload.cse.ucsc.edu/goldenPath/hg19/database/cytoBand.txt.gz + my $ktype = q[ + chr1 121500000 125000000 p11.1 acen + chr1 125000000 128900000 q11 acen + chr1 243700000 249250621 q44 gneg + chr10 38000000 40200000 p11.1 acen + chr10 40200000 42300000 q11.1 acen + chr10 130600000 135534747 q26.3 gneg + chr11 51600000 53700000 p11.11 acen + chr11 53700000 55700000 q11 acen + chr11 130800000 135006516 q25 gneg + chr12 33300000 35800000 p11.1 acen + chr12 35800000 38200000 q11 acen + chr12 129300000 133851895 q24.33 gneg + chr13 16300000 17900000 p11.1 acen + chr13 17900000 19500000 q11 acen + chr13 110300000 115169878 q34 gneg + chr14 16100000 17600000 p11.1 acen + chr14 17600000 19100000 q11.1 acen + chr14 104000000 107349540 q32.33 gneg + chr15 15800000 19000000 p11.1 acen + chr15 19000000 20700000 q11.1 acen + chr15 98500000 102531392 q26.3 gneg + chr16 34600000 36600000 p11.1 acen + chr16 36600000 38600000 q11.1 acen + chr16 88700000 90354753 q24.3 gneg + chr17 22200000 24000000 p11.1 acen + chr17 24000000 25800000 q11.1 acen + chr17 75300000 81195210 q25.3 gneg + chr18 15400000 17200000 p11.1 acen + chr18 17200000 19000000 q11.1 acen + chr18 73100000 78077248 q23 gneg + chr19 24400000 26500000 p11 acen + chr19 26500000 28600000 q11 acen + chr19 56300000 59128983 q13.43 gpos25 + chr2 90500000 93300000 p11.1 acen + chr2 93300000 96800000 q11.1 acen + chr2 237300000 243199373 q37.3 gneg + chr20 25600000 27500000 p11.1 acen + chr20 27500000 29400000 q11.1 acen + chr20 58400000 63025520 q13.33 gneg + chr21 10900000 13200000 p11.1 acen + chr21 13200000 14300000 q11.1 acen + chr21 42600000 48129895 q22.3 gneg + chr22 12200000 14700000 p11.1 acen + chr22 14700000 17900000 q11.1 acen + chr22 49400000 51304566 q13.33 gneg + chr3 87900000 91000000 p11.1 acen + chr3 91000000 93900000 q11.1 acen + chr3 192300000 198022430 q29 gneg + chr4 48200000 50400000 p11 acen + chr4 50400000 52700000 q11 acen + chr4 187100000 191154276 q35.2 gpos25 + chr5 46100000 48400000 p11 acen + chr5 48400000 50700000 q11.1 acen + chr5 176600000 180915260 q35.3 gneg + chr6 58700000 61000000 p11.1 acen + chr6 61000000 63300000 q11.1 acen + chr6 164500000 171115067 q27 gneg + chr7 58000000 59900000 p11.1 acen + chr7 59900000 61700000 q11.1 acen + chr7 155100000 159138663 q36.3 gneg + chr8 43100000 45600000 p11.1 acen + chr8 45600000 48100000 q11.1 acen + chr8 139900000 146364022 q24.3 gneg + chr9 47300000 49000000 p11.1 acen + chr9 49000000 50700000 q11 acen + chr9 137400000 141213431 q34.3 gneg + chrX 58100000 60600000 p11.1 acen + chrX 60600000 63000000 q11.1 acen + chrX 147100000 155270560 q28 gneg + ]; + my @lines = split(/\n/,$ktype); + my %chrs = (); + my $max_len = 0; + for my $line (@lines) + { + if ( $line =~ /^\s*$/ ) { next; } + $line =~ s/^\s*//; + $line =~ s/\s*$//; + my @items = split(/\s+/,$line); + my $chr = $items[0]; + my $start = $items[1]; + my $end = $items[2]; + $chr =~ s/^chr//; + if ( $items[-1] eq 'acen' ) + { + push @{$chrs{$chr}{acen}},$start; + push @{$chrs{$chr}{acen}},$end; + } + if ( !defined $chrs{$chr}{len} or $chrs{$chr}{len} < $end ) + { + $chrs{$chr}{len} = $end; + } + if ( $max_len < $end ) { $max_len = $end; } + } + for my $chr (keys %chrs) + { + splice(@{$chrs{$chr}{acen}},1,1); + } + $$opts{chrs} = \%chrs; + $$opts{max_chr_len} = $max_len; +} + + + + diff --git a/misc/guess-ploidy.py b/misc/guess-ploidy.py new file mode 100755 index 0000000..816a5c6 --- /dev/null +++ b/misc/guess-ploidy.py @@ -0,0 +1,117 @@ +#!/usr/bin/env python +# +# Plot the output of "bcftools +guess-ploidy -v" +# +# Copyright (C) 2016 Genome Research Ltd. +# +# Author: Petr Danecek +# +# Permission is hereby granted, free of charge, to any person obtaining a copy +# of this software and associated documentation files (the "Software"), to deal +# in the Software without restriction, including without limitation the rights +# to use, copy, modify, merge, publish, distribute, sublicense, and/or sell +# copies of the Software, and to permit persons to whom the Software is +# furnished to do so, subject to the following conditions: +# +# The above copyright notice and this permission notice shall be included in +# all copies or substantial portions of the Software. +# +# THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +# IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +# FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL +# THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER +# LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING +# FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER +# DEALINGS IN THE SOFTWARE. + +import matplotlib as mpl +mpl.use('Agg') +import matplotlib.pyplot as plt +import matplotlib.gridspec as gridspec +import random, math, sys +import csv +csv.register_dialect('tab', delimiter='\t', quoting=csv.QUOTE_NONE) + +if len(sys.argv) != 3: + print >> sys.stderr, 'About: Plot output of "bcftools +guess-ploidy -v"' + print >> sys.stderr, 'Usage: guess-ploidy.py ' + sys.exit() + +prefix = sys.argv[2] +dpi = 150 + +def add_value(dat,key,x,y): + if key not in dat: + dat[key] = [] + dat[key].append([x,y]) + +smpl2sex = {} +dat = {} +with open(sys.argv[1]) as f: + reader = csv.reader(f, 'tab') + for row in reader: + if row[0][0]=="#": continue + if row[0]=="SEX": + smpl = row[1] + sex = row[2] + phap = float(row[3]) + pdip = float(row[4]) + ndat = float(row[5]) + score = float(row[6]) + smpl2sex[smpl] = sex + add_value(dat,'score',smpl,score) + add_value(dat,'phap',smpl,phap) + add_value(dat,'pdip',smpl,pdip) + add_value(dat,'ndat',smpl,ndat) + +def sort_by_val(arr): + for x in (sorted(arr, key=lambda x:x[1])): + id = len(smpl2id) + smpl2id[x[0]] = id + arr = sorted(arr, key=lambda x:smpl2id[x[0]]) + return arr + +def select_sex(arr,sex): + out = [] + for x in arr: + if smpl2sex[x[0]]==sex: out.append(x) + return out + +col = {} +col['blue'] = '#396ab1' +col['orange'] = '#da7c30' +col['green'] = '#3e9651' +col['red'] = '#cc2529' +col['grey'] = '#000000' +col['purple'] = '#6b4c9a' +col['yellow'] = '#ccc210' + +if True: + fig,ax1 = plt.subplots(1,1,figsize=(6,4)) + smpl2id = {} + dat['score'] = sort_by_val(dat['score']) + dat['scoreM'] = select_sex(dat['score'],'M') + dat['scoreF'] = select_sex(dat['score'],'F') + ax2 = ax1.twinx() + plots = ax2.plot([smpl2id[x[0]] for x in dat['ndat']],[x[1] for x in dat['ndat']],'v',color=col['grey'],ms=2,label='Number of sites') + plots += ax1.plot([smpl2id[x[0]] for x in dat['phap']],[x[1] for x in dat['phap']],'.',color=col['blue'],ms=3,label='log P(haploid)') + plots += ax1.plot([smpl2id[x[0]] for x in dat['pdip']],[x[1] for x in dat['pdip']],'.',color=col['yellow'],ms=3,label='log P(diploid)') + plots += ax1.plot([smpl2id[x[0]] for x in dat['scoreM']],[x[1] for x in dat['scoreM']],'.',color=col['green'],label='Total score: Males') + plots += ax1.plot([smpl2id[x[0]] for x in dat['scoreF']],[x[1] for x in dat['scoreF']],'.',color=col['red'],label='Total score: Females') + labels = [l.get_label() for l in plots] + ax1.legend(plots,labels,loc='best', frameon=False, numpoints=1, prop={'size':9}) + ax1.set_zorder(ax2.get_zorder()+1) + ax1.patch.set_visible(False) + ax1.set_xlabel('Sample') + ax1.set_ylabel('Score') + ax2.set_ylabel('Number of sites') + ax2.set_yscale('log') + # ax1.set_yscale('log') + ax1.ticklabel_format(style='sci', scilimits=(-3,4), axis='x') + plt.subplots_adjust(left=0.13,right=0.89,bottom=0.13,top=0.9,hspace=0.1) + plt.savefig(prefix+'.png',dpi=dpi) + +plt.close() + + + diff --git a/misc/plot-roh.py b/misc/plot-roh.py new file mode 100755 index 0000000..e464c7a --- /dev/null +++ b/misc/plot-roh.py @@ -0,0 +1,253 @@ +#!/usr/bin/python + +import glob, gzip, csv, sys, os, copy +csv.register_dialect('tab', delimiter='\t', quoting=csv.QUOTE_NONE) + +dir = None +reg = {'chr':None,'beg':0,'end':(1<<32)-1} +min_length = 0 +min_markers = 0 +min_qual = 0 +interactive = False +if len(sys.argv) < 2: + print 'Usage: plot.py [OPTIONS] ' + print 'Options:' + print ' -i, --interactive Run interactively' + print ' -l, --min-length Filter input regions shorter than this [0]' + print ' -n, --min-markers Filter input regions with fewer marker than this [0]' + print ' -q, --min-qual Filter input regions with quality smaller than this [0]' + print ' -r, --region Plot this chromosome/region only' + sys.exit(1) +args = sys.argv[1:] +while len(args): + if args[0]=='-r' or args[0]=='--region': + args = args[1:] + x = args[0].split(':') + reg['chr'] = x[0] + if len(x)>1: + (reg['beg'],reg['end']) = x[1].split('-') + reg['beg'] = float(reg['beg']) + reg['end'] = float(reg['end']) + elif args[0]=='-i' or args[0]=='--interactive': + interactive = True + elif args[0]=='-l' or args[0]=='--min-length': + args = args[1:] + min_length = float(args[0]) + elif args[0]=='-n' or args[0]=='--min-markers': + args = args[1:] + min_markers = float(args[0]) + elif args[0]=='-q' or args[0]=='--min-qual': + args = args[1:] + min_qual = float(args[0]) + else: + dir = args[0] + args = args[1:] + +import matplotlib as mpl +for gui in ['TKAgg','GTKAgg','Qt4Agg','WXAgg','MacOSX']: + try: + mpl.use(gui,warn=False, force=True) + import matplotlib.pyplot as plt + import matplotlib.patches as patches + break + except: + continue + +cols = [ '#337ab7', '#5cb85c', '#5bc0de', '#f0ad4e', '#d9534f', 'grey', 'black' ] +mpl.rcParams['axes.color_cycle'] = cols + +globstr = os.path.join(dir, '*.txt.gz') +fnames = glob.glob(globstr) + +def next_region(rgs): + min = None + for smpl in rgs: + if len(rgs[smpl])==0: continue + reg = rgs[smpl][0] + if min==None: + min = [0,0] + min[0] = reg[0] + min[1] = reg[1] + if min[0] > reg[0]: min[0] = reg[0] + if min==None: return None + for smpl in rgs: + if len(rgs[smpl])==0: continue + reg = rgs[smpl][0] + if min[1] > reg[1]: min[1] = reg[1] + if min[1] > reg[0] - 1 and min[0] != reg[0]: min[1] = reg[0] - 1 + return min; + +def merge_regions(rg): + rgs = copy.deepcopy(rg) + out = {} + while True: + min = next_region(rgs) + if min==None: break + beg = min[0] + end = min[1] + smpls = [] + for smpl in rgs: + if len(rgs[smpl])==0: continue + reg = rgs[smpl][0] + if reg[0] > end: continue + if reg[1] > end: + rgs[smpl][0][0] = end + 1 + else: + rgs[smpl] = rgs[smpl][1:] + if smpl not in out: out[smpl] = [] + smpls.append(smpl) + if len(smpls)>1: + for smpl in smpls: out[smpl].append([beg,end]) + return out + + +smpl2y = {} +dat_gt = {} +dat_rg = {} +chrs = [] +for fname in fnames: + f = gzip.open(fname, 'rb') + reader = csv.reader(f, 'tab') + for row in reader: + if row[0]=='GT': + chr = row[1] + pos = int(row[2]) + if reg['chr']!=None and (chr!=reg['chr'] or posreg['end']): continue + smpl = row[3] + gt = row[4] + x = gt.split('/') + dsg = 2 + if x[0]!=x[1]: dsg = 1 + elif x[0]=='0': dsg = 0 + if chr not in dat_gt: + dat_gt[chr] = {} + chrs.append(chr) + if smpl not in dat_gt[chr]: + dat_gt[chr][smpl] = [] + if smpl not in smpl2y: + y = len(smpl2y) + smpl2y[smpl] = y + dat_gt[chr][smpl].append([pos,dsg]) + elif row[0]=='RG': + smpl = row[1] + chr = row[2] + beg = int(row[3]) + end = int(row[4]) + length= int(row[5]) + nmark = int(row[6]) + qual = float(row[7]) + if length < min_length: continue + if nmark < min_markers : continue + if qual < min_qual : continue + if reg['chr']!=None and (chr!=reg['chr'] or endreg['end']): continue + if chr not in dat_rg: dat_rg[chr] = {} + if smpl not in dat_rg[chr]: dat_rg[chr][smpl] = [] + if reg['chr']!=None: + if begreg['end']: end = reg['end'] + dat_rg[chr][smpl].append([beg,end]) + +off_list = [] +off_hash = {} +off = 0 +off_sep = 0 +dat_rg1 = {} +for chr in chrs: + if chr in dat_rg: + rg1 = merge_regions(dat_rg[chr]) + if len(rg1)!=0: dat_rg1[chr] = rg1 + off_hash[chr] = off + max_pos = 0 + for smpl in dat_gt[chr]: + if max_pos < dat_gt[chr][smpl][-1][0]: max_pos = dat_gt[chr][smpl][-1][0] + if off_sep==0: off_sep = max_pos*0.1 + off += max_pos + off_sep + off_list.append(off) + +height = len(fnames) +if len(fnames)>5: heigth = 5 +wh = 20,height + +def bignum(num): + s = str(num); out = ''; slen = len(s) + for i in range(slen): + out += s[i] + if i+1 x: break + off = off_list[i] + return 'chr%s:%s'%(chr,bignum(int(x - off))) + +if interactive: + fig, ax1 = plt.subplots(1, 1, figsize=wh, num=dir) + ax1.yaxis.set_ticks_position('none') + ax1.format_coord = format_coord + xtick_lbl = [] + xtick_pos = [] + for chr in dat_gt: + off = off_hash[chr] + xtick_lbl.append(chr) + xtick_pos.append(off) + icol = 0 + for smpl in dat_gt[chr]: + y = smpl2y[smpl] + if chr in dat_rg and smpl in dat_rg[chr]: + for rg in dat_rg[chr][smpl]: + rect = patches.Rectangle((rg[0]+off,3*y+0.5), rg[1]-rg[0]+1, 2, color='#dddddd') + ax1.add_patch(rect) + if chr in dat_rg1 and smpl in dat_rg1[chr]: + for rg in dat_rg1[chr][smpl]: + rect = patches.Rectangle((rg[0]+off,3*y+0.5), rg[1]-rg[0]+1, 2, color='#d9534f') + ax1.add_patch(rect) + ax1.plot([x[0]+off for x in dat_gt[chr][smpl]],[x[1]+3*y for x in dat_gt[chr][smpl]],'.',color=cols[icol]) + icol += 1 + if icol >= len(cols): 0 + ytick_lbl = [] + ytick_pos = [] + for chr in dat_gt: + for smpl in dat_gt[chr]: + ytick_lbl.append(smpl) + ytick_pos.append(3*smpl2y[smpl]+1) + break + ax1.set_xticks(xtick_pos) + ax1.set_xticklabels(xtick_lbl) + ax1.set_yticks(ytick_pos) + ax1.set_yticklabels(ytick_lbl) + ax1.set_ylim(0,3*len(smpl2y)+0.5) + plt.subplots_adjust(bottom=0.18,left=0.05,right=0.98) + plt.show() +else: + for chr in dat_gt: + fig, ax1 = plt.subplots(1, 1, figsize=wh) + ax1.yaxis.set_ticks_position('none') + ax1.format_coord = format_coord + tick_lbl = [] + tick_pos = [] + for smpl in dat_gt[chr]: + y = smpl2y[smpl] + tick_lbl.append(smpl) + tick_pos.append(3*y+1) + if chr in dat_rg and smpl in dat_rg[chr]: + for rg in dat_rg[chr][smpl]: + rect = patches.Rectangle((rg[0],3*y+0.5), rg[1]-rg[0]+1, 2, color='#dddddd') + ax1.add_patch(rect) + if chr in dat_rg and smpl in dat_rg1[chr]: + for rg in dat_rg1[chr][smpl]: + rect = patches.Rectangle((rg[0],3*y+0.5), rg[1]-rg[0]+1, 2, color='#d9534f') + ax1.add_patch(rect) + ax1.plot([x[0] for x in dat_gt[chr][smpl]],[x[1]+3*y for x in dat_gt[chr][smpl]],'.') + ax1.set_yticks(tick_pos) + ax1.set_yticklabels(tick_lbl) + ax1.set_xlabel('chr'+chr) + ax1.set_ylim(0,3*len(smpl2y)+0.5) + plt.subplots_adjust(bottom=0.18,left=0.1,right=0.95) + plt.savefig('rmme-chr'+chr+'.png',dpi=150) + plt.close() + + diff --git a/misc/plot-vcfstats b/misc/plot-vcfstats new file mode 100755 index 0000000..5751baa --- /dev/null +++ b/misc/plot-vcfstats @@ -0,0 +1,2036 @@ +#!/usr/bin/env perl +# +# Copyright (C) 2012-2014 Genome Research Ltd. +# +# Author: Petr Danecek +# +# Permission is hereby granted, free of charge, to any person obtaining a copy +# of this software and associated documentation files (the "Software"), to deal +# in the Software without restriction, including without limitation the rights +# to use, copy, modify, merge, publish, distribute, sublicense, and/or sell +# copies of the Software, and to permit persons to whom the Software is +# furnished to do so, subject to the following conditions: +# +# The above copyright notice and this permission notice shall be included in +# all copies or substantial portions of the Software. +# +# THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +# IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +# FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL +# THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER +# LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING +# FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER +# DEALINGS IN THE SOFTWARE. + +# Dependencies: +# - matplotlib +# http://matplotlib.sourceforge.net +# - LaTex/xcolor.sty +# Download .sty.gz LaTeX class style from http://www.ukern.de/tex/xcolor.html, +# unpack and install system-wide or place elsewhere and make available by +# setting the TEXINPUTS environment variable (note the colon) +# export TEXINPUTS=some/dir: +# The list of the recognised path can be obtained from `kpsepath tex` +# +# + +use strict; +use warnings; +use Carp; +use Storable qw(dclone); + +my $opts = parse_params(); +parse_vcfstats($opts); +merge_vcfstats($opts) if @{$$opts{vcfstats}} > 1; + +chdir($$opts{dir}); +if ( $$opts{make_plots} ) +{ + init_plots($opts); + plot_venn_bars($opts); + plot_counts_by_AF($opts); + plot_overlap_by_AF($opts); + plot_concordance_by_AF($opts); + plot_concordance_by_sample($opts); + for my $id (file_ids($opts)) + { + plot_tstv_by_AF($opts,$id); + plot_tstv_by_QUAL($opts,$id); + plot_indel_distribution($opts,$id); + plot_substitutions($opts,$id); + plot_per_sample_stats($opts,$id); + plot_DP($opts,$id); + plot_hwe($opts,$id); + } + plot($opts); +} +create_pdf($opts) unless !$$opts{make_pdf}; + +exit; + +#-------------------------------- + +sub error +{ + my (@msg) = @_; + if ( scalar @msg ) { confess @msg; } + die + "About: Plots output of \"bcftools stats\"\n", + "Usage: plot-vcfstats [OPTIONS] file.chk ...\n", + " plot-vcfstats -p outdir/ file.chk ...\n", + "Options:\n", + " -m, --merge Merge vcfstats files to STDOUT, skip plotting.\n", + " -p, --prefix Output directory.\n", + " -P, --no-PDF Skip the PDF creation step.\n", + " -r, --rasterize Rasterize PDF images for fast rendering.\n", + " -s, --sample-names Use sample names for xticks rather than numeric IDs.\n", + " -t, --title Identify files by these titles in plots. Can be given multiple times.\n", + " -T, --main-title Main title for the PDF.\n", + " -h, -?, --help This help message.\n", + "\n"; +} + + +sub parse_params +{ + $0 =~ s{^.+/}{}; + my $opts = + { + pdf_plots => 1, + use_sample_names => 0, + verbose => 1, + make_pdf => 1, + make_plots => 1, + merge => 0, + args => join(' ',$0,@ARGV), + img_width => 11/2.54, + img_height => 10/2.54, + id2col => [ 'orange', 'red', 'darkgreen' ], + tex => + { + slide3v => { height1 => '7cm', height2 => '7cm', height3 => '4.5cm' }, + slide3h => { width1 => '15cm', width2 => '10cm', width3 => '8cm' }, + }, + + # for file version sanity check + sections => + [ + { + id=>'ID', + header=>'Definition of sets', + exp=>"# ID\t[2]id\t[3]tab-separated file names" + }, + { + id=>'SN', + header=>'SN, Summary numbers', + exp=>"# SN\t[2]id\t[3]key\t[4]value" + }, + { + id=>'TSTV', + header=>'# TSTV, transition/transversions:', + exp=>"# TSTV\t[2]id\t[3]ts\t[4]tv\t[5]ts/tv\t[6]ts (1st ALT)\t[7]tv (1st ALT)\t[8]ts/tv (1st ALT)" + }, + { + id=>'SiS', + header=>'Sis, Singleton stats', + exp=>"# SiS\t[2]id\t[3]allele count\t[4]number of SNPs\t[5]number of transitions\t[6]number of transversions\t[7]number of indels\t[8]repeat-consistent\t[9]repeat-inconsistent\t[10]not applicable" + }, + { + id=>'AF', + header=>'AF, Stats by non-reference allele frequency', + exp=>"# AF\t[2]id\t[3]allele frequency\t[4]number of SNPs\t[5]number of transitions\t[6]number of transversions\t[7]number of indels\t[8]repeat-consistent\t[9]repeat-inconsistent\t[10]not applicable" + }, + { + id=>'IDD', + header=>'IDD, InDel distribution', + exp=>"# IDD\t[2]id\t[3]length (deletions negative)\t[4]count" + }, + { + id=>'ST', + header=>'ST, Substitution types', + exp=>"# ST\t[2]id\t[3]type\t[4]count" + }, + { + id=>'GCsAF', + header=>'GCsAF, Genotype concordance by non-reference allele frequency (SNPs)', + exp=>"# GCsAF\t[2]id\t[3]allele frequency\t[4]RR Hom matches\t[5]RA Het matches\t[6]AA Hom matches\t[7]RR Hom mismatches\t[8]RA Het mismatches\t[9]AA Hom mismatches\t[10]dosage r-squared\t[11]number of genotypes" + }, + { + id=>'GCiAF', + header=>'GCiAF, Genotype concordance by non-reference allele frequency (indels)', + exp=>"# GCiAF\t[2]id\t[3]allele frequency\t[4]RR Hom matches\t[5]RA Het matches\t[6]AA Hom matches\t[7]RR Hom mismatches\t[8]RA Het mismatches\t[9]AA Hom mismatches\t[10]dosage r-squared\t[11]number of genotypes" + }, + { + id=>'NRDs', + header=>'Non-Reference Discordance (NRD), SNPs', + exp=>"# NRDs\t[2]id\t[3]NRD\t[4]Ref/Ref discordance\t[5]Ref/Alt discordance\t[6]Alt/Alt discordance" + }, + { + id=>'NRDi', + header=>'Non-Reference Discordance (NRD), indels', + exp=>"# NRDi\t[2]id\t[3]NRD\t[4]Ref/Ref discordance\t[5]Ref/Alt discordance\t[6]Alt/Alt discordance" + }, + { + id=>'GCsS', + header=>'GCsS, Genotype concordance by sample (SNPs)', + exp=>"# GCsS\t[2]id\t[3]sample\t[4]non-reference discordance rate\t[5]RR Hom matches\t[6]RA Het matches\t[7]AA Hom matches\t[8]RR Hom mismatches\t[9]RA Het mismatches\t[10]AA Hom mismatches\t[11]dosage r-squared" + }, + { + id=>'GCiS', + header=>'GCiS, Genotype concordance by sample (indels)', + exp=>"# GCiS\t[2]id\t[3]sample\t[4]non-reference discordance rate\t[5]RR Hom matches\t[6]RA Het matches\t[7]AA Hom matches\t[8]RR Hom mismatches\t[9]RA Het mismatches\t[10]AA Hom mismatches\t[11]dosage r-squared" + }, + { + id=>'PSC', + header=>'PSC, Per-sample counts', + exp=>"# PSC\t[2]id\t[3]sample\t[4]nRefHom\t[5]nNonRefHom\t[6]nHets\t[7]nTransitions\t[8]nTransversions\t[9]nIndels\t[10]average depth\t[11]nSingletons" + }, + { + id=>'PSI', + header=>'PSI, Per-sample Indels', + exp=>"# PSI\t[2]id\t[3]sample\t[4]in-frame\t[5]out-frame\t[6]not applicable\t[7]out/(in+out) ratio\t[8]nHets\t[9]nAA" + }, + { + id=>'DP', + header=>'DP, Depth distribution', + exp=>"# DP\t[2]id\t[3]bin\t[4]number of genotypes\t[5]fraction of genotypes (%)\t[6]number of sites\t[7]fraction of sites (%)" + }, + { + id=>'FS', + header=>'FS, Indel frameshifts', + exp=>"# FS\t[2]id\t[3]in-frame\t[4]out-frame\t[5]not applicable\t[6]out/(in+out) ratio\t[7]in-frame (1st ALT)\t[8]out-frame (1st ALT)\t[9]not applicable (1st ALT)\t[10]out/(in+out) ratio (1st ALT)" + }, + { + id=>'ICS', + header=>'ICS, Indel context summary', + exp=>"# ICS\t[2]id\t[3]repeat-consistent\t[4]repeat-inconsistent\t[5]not applicable\t[6]c/(c+i) ratio" + }, + { + id=>'ICL', + header=>'ICL, Indel context by length', + exp=>"# ICL\t[2]id\t[3]length of repeat element\t[4]repeat-consistent deletions)\t[5]repeat-inconsistent deletions\t[6]consistent insertions\t[7]inconsistent insertions\t[8]c/(c+i) ratio" + }, + { + id=>'QUAL', + header=>'QUAL, Stats by quality', + exp=>"# QUAL\t[2]id\t[3]Quality\t[4]number of SNPs\t[5]number of transitions (1st ALT)\t[6]number of transversions (1st ALT)\t[7]number of indels" + }, + { + id=>'HWE', + header=>'HWE', + exp=>"# HWE\t[2]id\t[3]1st ALT allele frequency\t[4]Number of observations\t[5]25th percentile\t[6]median\t[7]75th percentile", + }, + ], + SN_keys=>[ + 'number of samples:', + 'number of records:', + 'number of no-ALTs:', + 'number of SNPs:', + 'number of MNPs:', + 'number of indels:', + 'number of others:', + 'number of multiallelic sites:', + 'number of multiallelic SNP sites:', + ], + }; + for my $sec (@{$$opts{sections}}) { $$opts{exp}{$$sec{id}} = $$sec{exp}; $$opts{id2sec}{$$sec{id}} = $sec; } + while (defined(my $arg=shift(@ARGV))) + { + if ( $arg eq '--no-plots' ) { $$opts{make_plots}=0; next; } + if ( $arg eq '-P' || $arg eq '--no-PDF' ) { $$opts{make_pdf}=0; next; } + if ( $arg eq '-r' || $arg eq '--rasterize' ) { $$opts{rasterize}=1; $$opts{pdf_plots} = 0; next; } + if ( $arg eq '-m' || $arg eq '--merge' ) { $$opts{make_plots}=0; $$opts{make_pdf}=0; $$opts{merge}=1; next; } + if ( $arg eq '-s' || $arg eq '--sample-names' ) { $$opts{use_sample_names}=1; next; } + if ( $arg eq '-t' || $arg eq '--title' ) { push @{$$opts{titles}},shift(@ARGV); next; } + if ( $arg eq '-T' || $arg eq '--main-title' ) { $$opts{main_title} = shift(@ARGV); next; } + if ( $arg eq '-p' || $arg eq '--prefix' ) { $$opts{prefix}=shift(@ARGV); next; } + if ( $arg eq '-?' || $arg eq '-h' || $arg eq '--help' ) { error(); } + if ( -e $arg ) { push @{$$opts{vcfstats}},$arg; next; } + error("Unknown parameter or non-existent file \"$arg\". Run -h for help.\n"); + } + if ( !exists($$opts{vcfstats}) ) { error(); } + if ( !exists($$opts{prefix}) ) + { + if ( !$$opts{merge} ) { error("Expected -p parameter.\n") } + $$opts{prefix} = '.'; + } + elsif ( $$opts{merge} ) { error("Only one of -p or -m should be given.\n"); } + if ( $$opts{merge} && @{$$opts{vcfstats}} < 2 ) { error("Nothing to merge\n") } + + $$opts{dir} = $$opts{prefix}; + $$opts{logfile} = "plot-vcfstats.log"; + if ( !-d $$opts{dir} ) { `mkdir -p $$opts{dir}`; } + `> $$opts{dir}/$$opts{logfile}` unless $$opts{merge}; + return $opts; +} + + +sub plot +{ + my ($opts) = @_; + if ( !exists($$opts{plt_fh}) ) { return; } + close($$opts{plt_fh}) or error("close $$opts{plt_fh}"); + my $cmd = "python $$opts{plt_file}"; + print STDERR "Plotting graphs: $cmd\n" unless !$$opts{verbose}; + system($cmd); + if ( $? ) { error("The command exited with non-zero status $?:\n\t$cmd\n\n"); } +} + + +sub parse_vcfstats +{ + my ($opts) = @_; + for (my $i=0; $i<@{$$opts{vcfstats}}; $i++) { parse_vcfstats1($opts,$i); } + + # Check sanity + if ( !exists($$opts{dat}{ID}{0}) ) + { + error("Sanity check failed: no stats found by vcfstats??\n"); + } + + # Set titles + my %file2title; + my %title2file; + if ( exists($$opts{titles}) ) + { + for (my $i=0; $i<@{$$opts{titles}}; $i++) + { + if ( !exists($$opts{dat}{ID}{$i}) ) { next; } + $file2title{$$opts{dat}{ID}{$i}[0][0]} = $$opts{titles}[$i]; + $title2file{$$opts{titles}[$i]} = $$opts{dat}{ID}{$i}[0][0]; + } + } + for my $id (file_ids($opts)) + { + if ( @{$$opts{dat}{ID}{$id}[0]}>1 ) { next; } # shared stats of two files + my $file = $$opts{dat}{ID}{$id}[0][0]; + if ( !exists($file2title{$file}) ) # create short title + { + my $bname = $file; + $bname =~ s{^.*/}{}; + $bname =~ s{\.vcf\.gz$}{}i; + if ( length($bname) > 5 ) { $bname = substr($bname,0,5); } + my $i = 0; + my $title = $bname; + while ( exists($title2file{$title}) ) { $title = $bname.chr(66+$i); $i++; } + $file2title{$file} = $title; + $title2file{$title} = $file; + } + } + for my $id (file_ids($opts)) + { + my @titles; + for my $file (@{$$opts{dat}{ID}{$id}[0]}) { push @titles, $file2title{$file} if $file2title{$file}; } + $$opts{title}{$id} = join(' + ',@titles); + } + + # mapping from file names to list of IDs + for my $id (file_ids($opts)) + { + my @files; + for my $file (@{$$opts{dat}{ID}{$id}[0]}) + { + push @{$$opts{file2ids}{$file}}, $id; + } + } + + # check sanity of the file merge: were the correct files merged? + if ( exists($$opts{coalesced_files}) && $$opts{verbose} ) + { + print STDERR "The vcfstats outputs have been merged as follows:\n"; + my %printed; + for my $id (keys %{$$opts{coalesced_files}}) + { + for (my $i=0; $i<@{$$opts{coalesced_files}{$id}}; $i++) + { + for (my $j=0; $j<@{$$opts{coalesced_files}{$id}[$i]}; $j++) + { + if ( exists($printed{$$opts{dat}{ID}{$id}[$i][$j]}) ) { next; } + print STDERR "\t$$opts{dat}{ID}{$id}[$i][$j]\n"; + for my $file (keys %{$$opts{coalesced_files}{$id}[$i][$j]}) + { + my $n = $$opts{coalesced_files}{$id}[$i][$j]{$file}; + print STDERR "\t\t$file", ($n>1 ? "\t..\t${n}x" : ''),"\n"; + } + $printed{$$opts{dat}{ID}{$id}[$i][$j]} = 1; + } + } + } + } +} + +sub add_to_values +{ + my ($dst,$src,$cmp) = @_; + my $id = 0; + my $is = 0; + while ($is<@$src) + { + while ( $id<@$dst && &$cmp($$src[$is][0],$$dst[$id][0])>0 ) { $id++; } + if ( $id<@$dst && !&$cmp($$src[$is][0],$$dst[$id][0]) ) + { + for (my $j=1; $j<@{$$src[$is]}; $j++) { $$dst[$id][$j] += $$src[$is][$j]; } + } + else { splice(@$dst,$id,0,$$src[$is]); } + $is++; + } +} + +sub add_to_sample_values +{ + my ($dst,$src) = @_; + my %id2i; + for (my $i=0; $i<@$dst; $i++) + { + $id2i{$$dst[$i][0]} = $i; + } + for (my $i=0; $i<@$src; $i++) + { + if ( !exists($id2i{$$src[$i][0]}) ) { error("Whoops, no such dst sample: $$src[$i][0]\n"); } + my $di = $id2i{$$src[$i][0]}; + for (my $j=1; $j<@{$$src[$i]}; $j++) + { + $$dst[$di][$j] += $$src[$i][$j]; + } + } +} + +sub merge_PSC +{ + my ($a,$b,$n) = @_; + for (my $i=0; $i<@$a; $i++) { $$a[$i][7] *= $n; } # average DP + add_to_sample_values($a,$b); + for (my $i=0; $i<@$a; $i++) { $$a[$i][7] /= $n+1; } +} + +sub merge_PSI +{ + my ($a,$b,$n) = @_; + add_to_sample_values($a,$b); + for (my $i=0; $i<@$b; $i++) { $$a[$i][4] = sprintf "%.2f", ($$a[$i][1]+$$a[$i][2] ? $$a[$i][2]/($$a[$i][1]+$$a[$i][2]) : 0); } +} + +sub rglob +{ + my ($a,$b) = @_; + if ( $a eq $b ) { return $a; } + $a =~ s/\*//; + my $la = length($a); + my $lb = length($b); + my $i = 0; + while ( $i<$la && $i<$lb && substr($a,$i,1) eq substr($b,$i,1) ) { $i++; } + $la--; $lb--; + while ( $la>$i && $lb>$i && substr($a,$la,1) eq substr($b,$lb,1) ) { $la--; $lb--; } + $la = $la==$i && $lb==$i ? 1 : $la-$i; + substr($a,$i,$la,'*'); + return $a; +} + +sub merge_id +{ + # merge id filenames + my ($opts,$dst,$src,$id) = @_; + for (my $i=0; $i<@{$$src{$id}}; $i++) + { + for (my $j=0; $j<@{$$src{$id}[$i]}; $j++) + { + my $gname = rglob($$dst{$id}[$i][$j], $$src{$id}[$i][$j]); + $$dst{$id}[$i][$j] = $gname; + $$opts{coalesced_files}{$id}[$i][$j]{$$src{$id}[$i][$j]}++; + } + } +} + +sub add_to_avg +{ + my ($dst,$src,$n) = @_; + for (my $i=0; $i<@$src; $i++) + { + if ( ref($$dst[$i]) eq 'ARRAY' ) + { + for (my $j=0; $j<@{$$dst[$i]}; $j++) + { + $$dst[$i][$j] = ($n*$$dst[$i][$j]+$$src[$i][$j])/($n+1); + } + } + else + { + $$dst[$i] = ($n*$$dst[$i]+$$src[$i])/($n+1); + } + } +} + +sub cmp_str($$) { my ($a,$b) = @_; return $a cmp $b; } +sub cmp_num($$) { my ($a,$b) = @_; return $a <=> $b; } +sub cmp_num_op($$) +{ + # numeric compare with operators + # Cases like <3, >500 make it complicated + my ($a,$b) = @_; + my $xa = '='; + my $xb = '='; + if ( $a=~/^(\D+)/ ) { $xa = $1; $a = $'; } + if ( $b=~/^(\D+)/ ) { $xb = $1; $b = $'; } + if ( $a==$b ) { return $xa cmp $xb; } + $a <=> $b; +} + +sub merge_dp +{ + my ($a,$b) = @_; + add_to_values($a,$b,\&cmp_num_op); + # recalculate fraction of GTs and fraction of sites, cannot be simply summed + my $gsum = 0; # genotype sum + my $ssum = 0; # site sum + for (my $i=0; $i<@$a; $i++) + { + $gsum += $$a[$i][1]; + if (@{$$a[$i]}>3) { + $ssum += $$a[$i][3]; + } + else{ + push @{$$a[$i]}, (0,0); # older stats files will not have last 2 columns for (number of sites, fraction of sites), so fill in as zero + } + } + for (my $i=0; $i<@$a; $i++) + { + $$a[$i][2] = $gsum ? $$a[$i][1]*100./$gsum : 0; + $$a[$i][4] = $ssum ? $$a[$i][3]*100./$ssum : 0; + } +} + +sub merge_GCsS +{ + my ($a,$b,$n) = @_; + # average the non-ref discordance rate + for (my $i=0; $i<@$a; $i++) { $$a[$i][1] *= $n; } + add_to_sample_values($a,$b); + for (my $i=0; $i<@$a; $i++) { $$a[$i][1] /= $n+1; } +} + +sub merge_FS +{ + my ($a,$b) = @_; + for (my $i=0; $i<@$a; $i++) + { + for (my $j=0; $j<3; $j++) { $$a[$i][$j] += $$b[$i][$j]; } + $$a[$i][3] = sprintf "%.2f", ($$a[$i][0] + $$a[$i][1]) ? $$a[$i][1]/($$a[$i][0] + $$a[$i][1]) : 0; + + for (my $j=4; $j<7; $j++) { $$a[$i][$j] += $$b[$i][$j]; } + $$a[$i][7] = sprintf "%.2f", ($$a[$i][4] + $$a[$i][5]) ? $$a[$i][5]/($$a[$i][4] + $$a[$i][5]) : 0; + } +} + +sub merge_ICS +{ + my ($a,$b) = @_; + for (my $i=0; $i<@$a; $i++) + { + for (my $j=0; $j<3; $j++) { $$a[$i][$j] += $$b[$i][$j]; } + $$a[$i][3] = sprintf "%.4f", ($$a[$i][0] + $$a[$i][1]) ? $$a[$i][0]/($$a[$i][0] + $$a[$i][1]) : 0; + } +} + +sub merge_ICL +{ + my ($a,$b) = @_; + for (my $i=0; $i<@$a; $i++) + { + for (my $j=1; $j<5; $j++) { $$a[$i][$j] += $$b[$i][$j]; } + $$a[$i][5] = sprintf "%.4f", ($$a[$i][2] + $$a[$i][4]) ? ($$a[$i][1] + $$a[$i][3])/($$a[$i][1] + $$a[$i][2] + $$a[$i][3] + $$a[$i][4]) : 0; + } +} + +sub merge_TSTV +{ + my ($a,$b) = @_; + for (my $i=0; $i<@$a; $i++) + { + for (my $j=0; $j<2; $j++) { $$a[$i][$j] += $$b[$i][$j]; } + $$a[$i][2] = sprintf "%.2f", $$a[$i][1] ? $$a[$i][0]/$$a[$i][1] : 0; + + for (my $j=3; $j<5; $j++) { $$a[$i][$j] += $$b[$i][$j]; } + $$a[$i][5] = sprintf "%.2f", $$a[$i][4] ? $$a[$i][3]/$$a[$i][4] : 0; + } +} + +sub merge_GCsAF +{ + my ($a,$b) = @_; + # recalculate r2 + for (my $i=0; $i<@$a; $i++) { $$a[$i][7] *= $$a[$i][8]; } + for (my $i=0; $i<@$b; $i++) { $$b[$i][7] *= $$b[$i][8]; } + add_to_values($a,$b,\&cmp_num_op); + for (my $i=0; $i<@$a; $i++) { $$a[$i][7] /= $$a[$i][8]; } +} + +sub parse_vcfstats1 +{ + my ($opts,$i) = @_; + my $file = $$opts{vcfstats}[$i]; + print STDERR "Parsing bcftools stats output: $file\n" unless !$$opts{verbose}; + open(my $fh,'<',$file) or error("$file: $!"); + my $line = <$fh>; + if ( !$line or !($line=~/^# This file was produced by \S*/) ) { error("Sanity check failed: was this file generated by bcftools stats?"); } + my %dat; + while ($line=<$fh>) + { + $line =~ s/\s*$//; + if ( $line=~/^#\s+(\S+)\t/ ) + { + $$opts{def_line}{$1} = $line; + next; + } + if ( $line=~/^#/ ) { next; } + my @items = split(/\t/,$line); + if ( $items[0] eq 'SN' ) + { + $dat{$items[1]}{$items[2]} = splice(@items,3); + next; + } + push @{$dat{$items[0]}{$items[1]}}, [splice(@items,2)]; + } + close($fh); + for my $a (keys %dat) + { + if ( !exists($$opts{dat}{$a}) ) { $$opts{dat}{$a} = $dat{$a}; next; } # first vcfstats file + for my $b (keys %{$dat{$a}}) + { + # Merging multiple vcfstats files. Honestly, this is quite hacky. + if ( !exists($$opts{dat}{$a}{$b}) ) { $$opts{dat}{$a}{$b} = $dat{$a}{$b}; next; } # copy all, first occurance + + if ( $a eq 'ID' ) { merge_id($opts,$$opts{dat}{$a},$dat{$a},$b); } + elsif ( ref($dat{$a}{$b}) ne 'ARRAY' ) { $$opts{dat}{$a}{$b} += $dat{$a}{$b} unless $b eq 'number of samples:'; } # SN, Summary numbers, do not sum sample counts + elsif ( $a eq 'NRDs' ) { add_to_avg($$opts{dat}{$a}{$b},$dat{$a}{$b},$i); } + elsif ( $a eq 'NRDi' ) { add_to_avg($$opts{dat}{$a}{$b},$dat{$a}{$b},$i); } + elsif ( $a eq 'DP' ) { merge_dp($$opts{dat}{$a}{$b},$dat{$a}{$b}); } + elsif ( $a eq 'GCsS' ) { merge_GCsS($$opts{dat}{$a}{$b},$dat{$a}{$b},$i); } + elsif ( $a eq 'GCiS' ) { merge_GCsS($$opts{dat}{$a}{$b},$dat{$a}{$b},$i); } + elsif ( $a eq 'GCsAF' ) { merge_GCsAF($$opts{dat}{$a}{$b},$dat{$a}{$b},$i); } + elsif ( $a eq 'GCiAF' ) { merge_GCsAF($$opts{dat}{$a}{$b},$dat{$a}{$b},$i); } + elsif ( $a eq 'ST' ) { add_to_values($$opts{dat}{$a}{$b},$dat{$a}{$b},\&cmp_str); } + elsif ( $a eq 'PSC') { merge_PSC($$opts{dat}{$a}{$b},$dat{$a}{$b},$i); } + elsif ( $a eq 'PSI') { merge_PSI($$opts{dat}{$a}{$b},$dat{$a}{$b},$i); } + elsif ( $a eq 'IDD') { add_to_values($$opts{dat}{$a}{$b},$dat{$a}{$b},\&cmp_num); } + elsif ( $a eq 'FS') { merge_FS($$opts{dat}{$a}{$b},$dat{$a}{$b}); } + elsif ( $a eq 'ICS') { merge_ICS($$opts{dat}{$a}{$b},$dat{$a}{$b}); } + elsif ( $a eq 'ICL') { merge_ICL($$opts{dat}{$a}{$b},$dat{$a}{$b}); } + elsif ( $a eq 'TSTV') { merge_TSTV($$opts{dat}{$a}{$b},$dat{$a}{$b},$i); } + elsif ( $a eq 'DBG' ) { next; } + else { add_to_values($$opts{dat}{$a}{$b},$dat{$a}{$b},\&cmp_num_op); } # SiS AF IDD + } + } +} + +sub file_ids +{ + my ($opts) = @_; + my $id = 0; + my @out; + while ( exists($$opts{dat}{ID}) && exists($$opts{dat}{ID}{$id}) ) { push @out, $id++; } + return @out; +} + +sub tprint +{ + my ($fh,@txt) = @_; + for my $txt (@txt) + { + $txt =~ s/\n[ \t]+/\n/g; # eat leading tabs + while ( ($txt =~ /\n\t*\\t/) ) + { + $txt =~ s/(\n\t*)\\t/$1\t/g; # replace escaped tabs (\\t) with tabs + } + print $fh $txt; + } +} + +sub init_plots +{ + my ($opts) = @_; + + $$opts{plt_file} = "plot.py"; + + my $titles = "# Title abbreviations:\n"; + for my $id (file_ids($opts)) + { + $titles .= "# \t $id .. $$opts{title}{$id} .. $$opts{dat}{ID}{$id}[0][0]\n"; + } + $titles .= "#"; + + open(my $fh,'>',$$opts{plt_file}) or error("$$opts{plt_file}: $!"); + tprint $fh, qq[ + # This file was produced by plot-vcfstats, the command line was: + # $$opts{args} + # + # Edit as necessary and recreate the plots by running + # python $$opts{plt_file} + # + $titles + + # Set to 1 to plot in PDF instead of PNG + pdf_plots = $$opts{pdf_plots} + + # Use logarithimic X axis for allele frequency plots + af_xlog = 0 + + # Plots to generate, set to 0 to disable + plot_venn_snps = 1 + plot_venn_indels = 1 + plot_tstv_by_sample = 1 + plot_hethom_by_sample = 1 + plot_snps_by_sample = 1 + plot_indels_by_sample = 1 + plot_singletons_by_sample = 1 + plot_depth_by_sample = 1 + plot_SNP_count_by_af = 1 + plot_Indel_count_by_af = 1 + plot_SNP_overlap_by_af = 1 + plot_Indel_overlap_by_af = 1 + plot_dp_dist = 1 + plot_hwe = 1 + plot_concordance_by_af = 1 + plot_r2_by_af = 1 + plot_discordance_by_sample = 1 + plot_tstv_by_af = 1 + plot_indel_dist = 1 + plot_tstv_by_qual = 1 + plot_substitutions = 1 + + + # Set to 1 to use sample names for xticks instead of numeric sequential IDs + # and adjust margins and font properties if necessary + sample_names = $$opts{use_sample_names} + sample_margins = {'right':0.98, 'left':0.07, 'bottom':0.2} + sample_font = {'rotation':45, 'ha':'right', 'fontsize':8} + + if sample_names==0: sample_margins=(); sample_font=(); + + + #------------------------------------------------- + + + import matplotlib as mpl + mpl.use('Agg') + import matplotlib.pyplot as plt + + import csv + csv.register_dialect('tab', delimiter='\\t', quoting=csv.QUOTE_NONE) + + import numpy + def smooth(x,window_len=11,window='hanning'): + \\tif x.ndim != 1: raise ValueError("The function 'smooth' only accepts 1 dimension arrays.") + \\tif x.size < window_len: return x + \\tif window_len<3: return x + \\tif not window in ['flat', 'hanning', 'hamming', 'bartlett', 'blackman']: raise ValueError("Window is on of 'flat', 'hanning', 'hamming', 'bartlett', 'blackman'") + \\ts = numpy.r_[x[window_len-1:0:-1],x,x[-1:-window_len:-1]] + \\tif window == 'flat': # moving average + \\t\\tw = numpy.ones(window_len,'d') + \\telse: + \\t\\tw = eval('numpy.'+window+'(window_len)') + \\ty = numpy.convolve(w/w.sum(),s,mode='valid') + \\treturn y[(window_len/2-1):-(window_len/2)] + + ]; + $$opts{plt_fh} = $fh; +} + +sub percentile +{ + my ($p,@vals) = @_; + my $N = 0; + for my $val (@vals) { $N += $val; } + my $n = $p*($N+1)/100.; + my $k = int($n); + my $d = $n-$k; + if ( $k<=0 ) { return 0; } + if ( $k>=$N ) { return scalar @vals-1; } + my $cnt; + for (my $i=0; $i<@vals; $i++) + { + $cnt += $vals[$i]; + if ( $cnt>=$k ) { return $i; } + } + error("FIXME: this should not happen [percentile]\n"); +} + +sub get_values +{ + my ($opts,$id,$key,$i,$j) = @_; + if ( !exists($$opts{dat}{$key}) ) { return (); } + if ( !exists($$opts{dat}{$key}{$id}) ) { return (); } + my $fields_ok = 1; + if ( !exists($$opts{exp}{$key}) ) { error("todo: sanity check for $key\n"); } + if ( exists($$opts{def_line}{$key}) && $$opts{def_line}{$key} ne $$opts{exp}{$key} && !$$opts{def_line_warned}{$key} ) + { + warn("Warning: Possible version mismatch, the definition line differs\n\texpected: $$opts{exp}{$key}\n\tfound: $$opts{def_line}{$key}\n"); + $$opts{def_line_warned}{$key} = 1; + } + if ( defined $i ) + { + if ( defined $j ) { return $$opts{dat}{$key}{$id}[$i][$j]; } + return (@{$$opts{dat}{$key}{$id}[$i]}); + } + return (@{$$opts{dat}{$key}{$id}}); +} + +sub get_value +{ + my ($opts,$id,$key) = @_; + if ( !exists($$opts{dat}{$id}) ) { return undef; } + if ( !exists($$opts{dat}{$id}{$key}) ) { return undef} + return $$opts{dat}{$id}{$key}; +} + +sub plot_venn_bars +{ + my ($opts) = @_; + + my @ids = file_ids($opts); + if ( @ids != 3 ) { return; } + + my (@snps,@indels,@tstv,@snp_titles,@indel_titles); + for my $id (0..2) + { + push @snps, get_value($opts,$id,'number of SNPs:'); + push @indels, get_value($opts,$id,'number of indels:'); + push @tstv, sprintf("%.2f",get_values($opts,$id,'TSTV',0,5)); + push @snp_titles, "$$opts{title}{$id}\\nts/tv $tstv[$id]\\n" .bignum($snps[$id]); + my @fs = get_values($opts,$id,'FS'); + my $fs = @fs ? "frm $fs[0][3]\\n" : ''; + push @indel_titles, "$$opts{title}{$id}\\n$fs" .bignum($indels[$id]); + } + + my $fh = $$opts{plt_fh}; + tprint $fh, qq[ + + if plot_venn_snps: + \\tfig = plt.figure(figsize=($$opts{img_width},$$opts{img_height})) + \\tax1 = fig.add_subplot(111) + \\tax1.bar([1,2,3],[$snps[0],$snps[2],$snps[1]],align='center',color='$$opts{id2col}[0]',width=0.3) + \\tax1.ticklabel_format(style='sci', scilimits=(0,0), axis='y') + \\tax1.set_xlim(0.5,3.5) + \\tplt.xticks([1,2,3],('$snp_titles[0]','$snp_titles[2]','$snp_titles[1]')) + \\tplt.title('Number of SNPs') + \\tplt.subplots_adjust(right=0.95,bottom=0.15) + \\tplt.savefig('venn_bars.snps.png') + \\tif pdf_plots: plt.savefig('venn_bars.snps.pdf') + \\tplt.close() + + + if plot_venn_indels: + \\tfig = plt.figure(figsize=($$opts{img_width},$$opts{img_height})) + \\tax1 = fig.add_subplot(111) + \\tax1.bar([1,2,3],[$indels[0],$indels[2],$indels[1]],align='center',color='$$opts{id2col}[1]',width=0.3) + \\tax1.ticklabel_format(style='sci', scilimits=(0,0), axis='y') + \\tax1.set_xlim(0.5,3.5) + \\tplt.xticks([1,2,3],('$indel_titles[0]','$indel_titles[2]','$indel_titles[1]')) + \\tplt.title('Number of indels') + \\tplt.subplots_adjust(right=0.95,bottom=0.15) + \\tplt.savefig('venn_bars.indels.png') + \\tif pdf_plots: plt.savefig('venn_bars.indels.pdf') + \\tplt.close() + + ]; +} + +sub plot_per_sample_stats +{ + my ($opts,$id) = @_; + my @vals = get_values($opts,$id,'PSC'); + if ( !@vals ) { return; } + + my $fh = $$opts{plt_fh}; + my $img = "tstv_by_sample.$id"; + my $img2 = "hets_by_sample.$id"; + my $img3 = "snps_by_sample.$id"; + my $img4 = "indels_by_sample.$id"; + my $img5 = "singletons_by_sample.$id"; + my $img6 = "dp_by_sample.$id"; + + open(my $tfh,'>',"$img.dat") or error("$img.dat: $!"); + print $tfh "# [1]Sample ID\t[2]ts/tv\t[3]het/hom\t[4]nSNPs\t[5]nIndels\t[6]Average depth\t[7]nSingletons\t[8]Sample name\n"; + for (my $i=0; $i<@vals; $i++) + { + my $tstv = $vals[$i][5] ? $vals[$i][4]/$vals[$i][5] : 0; + my $hethom = $vals[$i][2] ? $vals[$i][3]/$vals[$i][2] : 0; + printf $tfh "%d\t%f\t%f\t%d\t%d\t%f\t%d\t%s\n", $i, $tstv, $hethom, $vals[$i][4]+$vals[$i][5], $vals[$i][6], $vals[$i][7], $vals[$i][8], $vals[$i][0]; + } + close($tfh); + + tprint $fh, " + + dat = [] + with open('$img.dat', 'rb') as f: + \\treader = csv.reader(f, 'tab') + \\tfor row in reader: + \\t\\tif row[0][0] != '#': dat.append(row) + + if plot_tstv_by_sample: + \\tfig = plt.figure(figsize=(2*$$opts{img_width},$$opts{img_height}*0.7)) + \\tax1 = fig.add_subplot(111) + \\tax1.plot([row[0] for row in dat], [row[1] for row in dat], 'o', color='$$opts{id2col}[$id]',mec='$$opts{id2col}[$id]') + \\tax1.set_ylabel('Ts/Tv') + \\tax1.set_ylim(min(float(row[1]) for row in dat)-0.1,max(float(row[1]) for row in dat)+0.1) + \\tif sample_names: + \\t\\t plt.xticks([int(row[0]) for row in dat],[row[7] for row in dat],**sample_font) + \\t\\t plt.subplots_adjust(**sample_margins) + \\telse: + \\t\\t plt.subplots_adjust(right=0.98,left=0.07,bottom=0.17) + \\t\\t ax1.set_xlabel('Sample ID') + \\tplt.title('$$opts{title}{$id}') + \\tplt.savefig('$img.png') + \\tif pdf_plots: plt.savefig('$img.pdf') + \\tplt.close() + + + if plot_hethom_by_sample: + \\tfig = plt.figure(figsize=(2*$$opts{img_width},$$opts{img_height}*0.7)) + \\tax1 = fig.add_subplot(111) + \\tax1.plot([row[0] for row in dat], [row[2] for row in dat], 'o', color='$$opts{id2col}[$id]',mec='$$opts{id2col}[$id]') + \\tax1.set_ylabel('nHet(RA) / nHom(AA)') + \\tax1.ticklabel_format(style='sci', scilimits=(0,0), axis='y') + \\tif sample_names: + \\t\\t plt.xticks([int(row[0]) for row in dat],[row[7] for row in dat],**sample_font) + \\t\\t plt.subplots_adjust(**sample_margins) + \\telse: + \\t\\t plt.subplots_adjust(right=0.98,left=0.07,bottom=0.17) + \\t\\t ax1.set_xlabel('Sample ID') + \\tplt.title('$$opts{title}{$id}') + \\tplt.savefig('$img2.png') + \\tif pdf_plots: plt.savefig('$img2.pdf') + \\tplt.close() + + + if plot_snps_by_sample: + \\tfig = plt.figure(figsize=(2*$$opts{img_width},$$opts{img_height}*0.7)) + \\tax1 = fig.add_subplot(111) + \\tax1.plot([row[0] for row in dat], [row[3] for row in dat], 'o', color='$$opts{id2col}[$id]',mec='$$opts{id2col}[$id]') + \\tax1.set_ylabel('Number of SNPs') + \\tax1.ticklabel_format(style='sci', scilimits=(0,0), axis='y') + \\tif sample_names: + \\t\\t plt.xticks([int(row[0]) for row in dat],[row[7] for row in dat],**sample_font) + \\t\\t plt.subplots_adjust(**sample_margins) + \\telse: + \\t\\t plt.subplots_adjust(right=0.98,left=0.07,bottom=0.17) + \\t\\t ax1.set_xlabel('Sample ID') + \\tplt.title('$$opts{title}{$id}') + \\tplt.savefig('$img3.png') + \\tif pdf_plots: plt.savefig('$img3.pdf') + \\tplt.close() + + + if plot_indels_by_sample: + \\tfig = plt.figure(figsize=(2*$$opts{img_width},$$opts{img_height}*0.7)) + \\tax1 = fig.add_subplot(111) + \\tax1.plot([row[0] for row in dat], [row[4] for row in dat], 'o', color='$$opts{id2col}[$id]',mec='$$opts{id2col}[$id]') + \\tax1.set_ylabel('Number of indels') + \\tax1.ticklabel_format(style='sci', scilimits=(0,0), axis='y') + \\tif sample_names: + \\t\\t plt.xticks([int(row[0]) for row in dat],[row[7] for row in dat],**sample_font) + \\t\\t plt.subplots_adjust(**sample_margins) + \\telse: + \\t\\t plt.subplots_adjust(right=0.98,left=0.07,bottom=0.17) + \\t\\t ax1.set_xlabel('Sample ID') + \\tplt.title('$$opts{title}{$id}') + \\tplt.savefig('$img4.png') + \\tif pdf_plots: plt.savefig('$img4.pdf') + \\tplt.close() + + + if plot_singletons_by_sample: + \\tfig = plt.figure(figsize=(2*$$opts{img_width},$$opts{img_height}*0.7)) + \\tax1 = fig.add_subplot(111) + \\tax1.plot([row[0] for row in dat], [row[6] for row in dat], 'o', color='$$opts{id2col}[$id]',mec='$$opts{id2col}[$id]') + \\tax1.set_ylabel('Number of singletons') + \\tax1.ticklabel_format(style='sci', scilimits=(0,0), axis='y') + \\tif sample_names: + \\t\\t plt.xticks([int(row[0]) for row in dat],[row[7] for row in dat],**sample_font) + \\t\\t plt.subplots_adjust(**sample_margins) + \\telse: + \\t\\t plt.subplots_adjust(right=0.98,left=0.07,bottom=0.17) + \\t\\t ax1.set_xlabel('Sample ID') + \\tplt.title('$$opts{title}{$id}') + \\tplt.savefig('$img5.png') + \\tif pdf_plots: plt.savefig('$img5.pdf') + \\tplt.close() + + + if plot_depth_by_sample: + \\tfig = plt.figure(figsize=(2*$$opts{img_width},$$opts{img_height}*0.7)) + \\tax1 = fig.add_subplot(111) + \\tax1.plot([row[0] for row in dat], [row[5] for row in dat], 'o', color='$$opts{id2col}[$id]',mec='$$opts{id2col}[$id]') + \\tax1.set_ylabel('Average depth') + \\tax1.ticklabel_format(style='sci', scilimits=(0,0), axis='y') + \\tif sample_names: + \\t\\t plt.xticks([int(row[0]) for row in dat],[row[7] for row in dat],**sample_font) + \\t\\t plt.subplots_adjust(**sample_margins) + \\telse: + \\t\\t plt.subplots_adjust(right=0.98,left=0.07,bottom=0.17) + \\t\\t ax1.set_xlabel('Sample ID') + \\tplt.title('$$opts{title}{$id}') + \\tplt.savefig('$img6.png') + \\tif pdf_plots: plt.savefig('$img6.pdf') + \\tplt.close() + + "; +} + +sub plot_DP +{ + my ($opts,$id) = @_; + my @vals = get_values($opts,$id,'DP'); + if ( !@vals ) { return; } + + my $fh = $$opts{plt_fh}; + my $img = "depth.$id"; + + open(my $tfh,'>',"$img.dat") or error("$img.dat: $!"); + print $tfh "# [1]Depth\t[2]Cumulative number of genotypes\t[3]Number of genotypes\n"; + my $sum = 0; + for (my $i=0; $i<@vals; $i++) + { + if ( $sum>99. ) { last; } + if ( !($vals[$i][0]=~/^\d+$/) ) { next; } # DP ">500" case + $sum += $vals[$i][2]; + printf $tfh "%d\t%f\t%f\n", $vals[$i][0], $sum, $vals[$i][2]; + } + close($tfh); + + tprint $fh, " + + dat = [] + with open('$img.dat', 'rb') as f: + \\treader = csv.reader(f, 'tab') + \\tfor row in reader: + \\t\\tif row[0][0] != '#': dat.append(row) + + if plot_dp_dist: + \\tfig = plt.figure(figsize=($$opts{img_width},$$opts{img_height})) + \\tax1 = fig.add_subplot(111) + \\tax1.plot([row[0] for row in dat], [row[2] for row in dat], '-^', color='k') + \\tax1.set_ylabel('Number of genotypes [%]',color='k') + \\tax1.set_xlabel('Depth') + \\tax2 = ax1.twinx() + \\tax2.plot([row[0] for row in dat], [row[1] for row in dat], '-o', color='$$opts{id2col}[$id]') + \\tax2.set_ylabel('Cumulative number of genotypes [%]',color='$$opts{id2col}[$id]') + \\tfor tl in ax2.get_yticklabels(): tl.set_color('$$opts{id2col}[$id]') + \\tplt.subplots_adjust(left=0.15,bottom=0.15,right=0.87) + \\tplt.title('$$opts{title}{$id}') + \\tplt.savefig('$img.png') + \\tif pdf_plots: plt.savefig('$img.pdf') + \\tplt.close() + + "; +} + +sub plot_hwe +{ + my ($opts,$id) = @_; + my @vals = get_values($opts,$id,'HWE'); + if ( !@vals ) { return; } + + my $fh = $$opts{plt_fh}; + my $img = "hwe.$id"; + + open(my $tfh,'>',"$img.dat") or error("$img.dat: $!"); + print $tfh "# [1]Allele Frequency\t[2]Depth\t[3]Number of hets (median)\t[4]Number of hets (25-75th percentile)\n"; + for (my $i=0; $i<@vals; $i++) + { + if ( !$vals[$i][1] ) { next; } + print $tfh join("\t", @{$vals[$i]}), "\n"; + } + close($tfh); + + tprint $fh, " + + + dat = [] + with open('$img.dat', 'rb') as f: + \\treader = csv.reader(f, 'tab') + \\tfor row in reader: + \\t\\tif row[0][0] != '#': dat.append(row) + + if plot_hwe and len(dat)>1: + \\tx = [float(row[0]) for row in dat] + \\ty1 = smooth(numpy.array([float(row[2]) for row in dat]),40,'hanning') + \\ty2 = smooth(numpy.array([float(row[3]) for row in dat]),40,'hanning') + \\ty3 = smooth(numpy.array([float(row[4]) for row in dat]),40,'hanning') + \\tdp = smooth(numpy.array([float(row[1]) for row in dat]),40,'hanning') + \\thwe = [] + \\tfor af in x: hwe.append(2*af*(1-af)) + + \\tfig = plt.figure(figsize=($$opts{img_width},$$opts{img_height})) + \\tax1 = fig.add_subplot(111) + \\tplots = ax1.plot(x,hwe,'--',color='#ff9900',label='HWE') + \\tplots += ax1.plot(x,y2,color='#ff9900',label='Median') + \\tplots += ax1.plot(x,y3,color='#ffe0b2',label='25-75th percentile') + \\tax1.fill_between(x,y1,y3, facecolor='#ffeacc',edgecolor='#ffe0b2') + \\tax1.set_ylabel('Fraction of hets',color='#ff9900') + \\tax1.set_xlabel('Allele frequency') + \\tfor tl in ax1.get_yticklabels(): tl.set_color('#ff9900') + \\tax2 = ax1.twinx() + \\tplots += ax2.plot(x,dp, 'k', label='Number of sites') + \\tax2.set_ylabel('Number of sites') + \\tax2.set_yscale('log') + \\tif af_xlog: ax1.set_xscale('log') + \\tif af_xlog: ax2.set_xscale('log') + \\tlabels = [l.get_label() for l in plots] + \\tplt.legend(plots,labels,numpoints=1,markerscale=2,loc='center',prop={'size':9},frameon=False) + \\tplt.subplots_adjust(left=0.15,bottom=0.15,right=0.86) + \\tplt.title('$$opts{title}{$id}') + \\tplt.savefig('$img.png') + \\tif pdf_plots: plt.savefig('$img.pdf') + \\tplt.close() + + "; +} + +sub plot_tstv_by_AF +{ + my ($opts,$id) = @_; + my @vals = get_values($opts,$id,'AF'); + if ( !@vals ) { return; } + + my $fh = $$opts{plt_fh}; + my $img = "tstv_by_af.$id"; + my $vals = rebin_values(\@vals,8,0); + + + open(my $tfh,'>',"$img.dat") or error("$img.dat: $!"); + print $tfh "# [1]Allele frequency\t[2]Number of sites\t[3]ts/tv\n"; + for (my $i=0; $i<@$vals; $i++) + { + if ( $$vals[$i][2] + $$vals[$i][3] == 0 ) { next; } + printf $tfh "%f\t%d\t%f\n", + $$vals[$i][0], + $$vals[$i][2] + $$vals[$i][3], + $$vals[$i][3] ? $$vals[$i][2]/$$vals[$i][3]: 0; + } + close($tfh); + + tprint $fh, " + + dat = [] + with open('$img.dat', 'rb') as f: + \\treader = csv.reader(f, 'tab') + \\tfor row in reader: + \\t\\tif row[0][0] != '#': dat.append([float(x) for x in row]) + + + if plot_tstv_by_af and len(dat)>2: + \\tfig = plt.figure(figsize=($$opts{img_width},$$opts{img_height})) + \\tax1 = fig.add_subplot(111) + \\tax1.plot([row[0] for row in dat], [row[1] for row in dat], '-o',color='k',mec='k',markersize=3) + \\tax1.set_ylabel('Number of sites',color='k') + \\tax1.set_yscale('log') + \\t#ax1.ticklabel_format(style='sci', scilimits=(0,0), axis='y') + \\tfor tl in ax1.get_yticklabels(): tl.set_color('k') + \\tax1.set_xlabel('Non-ref allele frequency') + \\tax2 = ax1.twinx() + \\tax2.plot([row[0] for row in dat], [row[2] for row in dat], '-o',color='$$opts{id2col}[$id]',mec='$$opts{id2col}[$id]',markersize=3) + \\tax2.set_ylabel('Ts/Tv',color='$$opts{id2col}[$id]') + \\tax2.set_ylim(0,0.5+max(3,max(row[2] for row in dat))) + \\tax1.set_xlim(0,1) + \\tfor tl in ax2.get_yticklabels(): tl.set_color('$$opts{id2col}[$id]') + \\tplt.subplots_adjust(right=0.88,left=0.15,bottom=0.11) + \\tplt.title('$$opts{title}{$id}') + \\tplt.savefig('$img.png') + \\tif pdf_plots: plt.savefig('$img.pdf') + \\tplt.close() + + "; +} + +sub plot_tstv_by_QUAL +{ + my ($opts,$id) = @_; + my @vals = get_values($opts,$id,'QUAL'); + if ( !@vals ) { return; } + + my $fh = $$opts{plt_fh}; + my $img = "tstv_by_qual.$id"; + + open(my $tfh,'>',"$img.dat") or error("$img.dat: $!"); + print $tfh "# [1]Quality\t[2]Number of sites\t[3]Marginal Ts/Tv\n"; + + my @dat = (); + my $ntot = 0; + for my $val (@vals) + { + push @dat, [ $$val[0], $$val[2], $$val[3] ]; # qual, nts, ntv + $ntot += $$val[2] + $$val[3]; + } + my @sdat = sort { $$b[0] <=> $$a[0] } @dat; + push @sdat, [-1]; + my $dn = $ntot*0.05; + my $qprev = $sdat[0][0]; + my $nts = 0; + my $ntv = 0; + my $nout = 0; + for my $rec (@sdat) + { + if ( $$rec[0]==-1 or $nts+$ntv > $dn ) + { + if ( $ntv ) { printf $tfh "$qprev\t%d\t%f\n", $nts+$ntv+$nout,$nts/$ntv; } + if ( $$rec[0]==-1 ) { last; } + $nout += $nts+$ntv; + $nts = 0; + $ntv = 0; + $qprev = $$rec[0]; + } + $nts += $$rec[1]; + $ntv += $$rec[2]; + } + close($tfh) or error("close $img.dat"); + + tprint $fh, " + + dat = [] + with open('$img.dat', 'rb') as f: + \\treader = csv.reader(f, 'tab') + \\tfor row in reader: + \\t\\tif row[0][0] != '#': dat.append([float(x) for x in row]) + + if plot_tstv_by_qual and len(dat)>2: + \\tfig = plt.figure(figsize=($$opts{img_width},$$opts{img_height})) + \\tax1 = fig.add_subplot(111) + \\tax1.plot([row[1] for row in dat], [row[2] for row in dat], '^-', ms=3, mec='$$opts{id2col}[$id]', color='$$opts{id2col}[$id]') + \\tax1.set_ylabel('Ts/Tv',fontsize=10) + \\tax1.set_xlabel('Number of sites\\n(sorted by QUAL, descending)',fontsize=10) + \\tax1.ticklabel_format(style='sci', scilimits=(-3,2), axis='x') + \\tax1.set_ylim(min(2,min(row[2] for row in dat))-0.3,0.3+max(2.2,max(row[2] for row in dat))) + + \\tplt.subplots_adjust(right=0.88,left=0.15,bottom=0.15) + \\tplt.title('$$opts{title}{$id}') + \\tplt.savefig('$img.png') + \\tif pdf_plots: plt.savefig('$img.pdf') + \\tplt.close() + + "; +} + +sub rebin_values +{ + my ($vals,$bin_size,$col,%args) = @_; + my %avg = exists($args{avg}) ? map {$_=>1} @{$args{avg}} : (); + my $prev = $$vals[0][$col]; + my $iout = 0; + my $nsum = 0; + my (@dat,@out); + for (my $i=0; $i<@$vals; $i++) + { + for (my $icol=0; $icol<@{$$vals[$i]}; $icol++) + { + if ( $icol==$col ) { next; } + $dat[$icol] += $$vals[$i][$icol]; + } + $nsum++; + if ( $i+1<@$vals && $$vals[$i][$col] - $prev < $bin_size ) { next; } + $dat[$col] = $prev; + for (my $icol=0; $icol<@{$$vals[$i]}; $icol++) + { + $out[$iout][$icol] = $dat[$icol] ? $dat[$icol] : 0; + if ( $avg{$icol} && $nsum ) { $out[$iout][$icol] /= $nsum; } + } + $nsum = 0; + @dat = (); + $iout++; + $prev = $$vals[$i][$col]; + } + return \@out; +} + +sub plot_concordance_by_AF +{ + my ($opts) = @_; + my @vals = get_values($opts,2,'GCsAF'); + if ( !@vals ) { return; } + + # create a local copy and prepare r2 for rebinning + @vals = @{ dclone(\@vals) }; + for (my $i=0; $i<@vals; $i++) { $vals[$i][7] *= $vals[$i][8]; } + my $vals = rebin_values(\@vals,0.01,0); + my $fh = $$opts{plt_fh}; + my $img = "gts_by_af"; + my $img2 = "r2_by_af"; + + open(my $tfh,'>',"$img.dat") or error("$img.dat: $!"); + print $tfh "# [1]Allele Frequency\t[2]RR concordance\t[3]RA concordance\t[4]AA concordance\t[5]nRR\t[6]nRA\t[7]nAA\t[8]R^2\t[9]Number of genotypes\n"; + for (my $i=0; $i<@$vals; $i++) + { + printf $tfh "%f\t%f\t%f\t%f\t%d\t%d\t%d\t%f\t%d\n", + $$vals[$i][0], + $$vals[$i][1]+$$vals[$i][4] ? $$vals[$i][1]/($$vals[$i][1]+$$vals[$i][4]) : 1, + $$vals[$i][2]+$$vals[$i][5] ? $$vals[$i][2]/($$vals[$i][2]+$$vals[$i][5]) : 1, + $$vals[$i][3]+$$vals[$i][6] ? $$vals[$i][3]/($$vals[$i][3]+$$vals[$i][6]) : 1, + $$vals[$i][1]+$$vals[$i][4], + $$vals[$i][2]+$$vals[$i][5], + $$vals[$i][3]+$$vals[$i][6], + $$vals[$i][8] ? $$vals[$i][7]/$$vals[$i][8] : 1, + $$vals[$i][8]; + } + close($tfh); + + tprint $fh, " + + dat = [] + with open('$img.dat', 'rb') as f: + \\treader = csv.reader(f, 'tab') + \\tfor row in reader: + \\t\\tif row[0][0] != '#': dat.append(row) + + if plot_concordance_by_af and len(dat)>1: + \\tfig = plt.figure(figsize=($$opts{img_width}*1.2,$$opts{img_height})) + \\tax1 = fig.add_subplot(111) + \\tax1.plot([row[0] for row in dat], [row[1] for row in dat],'.',color='$$opts{id2col}[1]',label='Hom RR') + \\tax1.plot([row[0] for row in dat], [row[2] for row in dat],'.',color='$$opts{id2col}[0]',label='Het RA') + \\tax1.plot([row[0] for row in dat], [row[3] for row in dat],'.',color='k',label='Hom AA') + \\tax1.set_xlabel('Non-ref allele frequency') + \\tax1.set_ylabel('Concordance') + \\tleg = ax1.legend(title='Concordance:',numpoints=1,markerscale=2,loc='best',prop={'size':9}) + \\tleg.draw_frame(False) + \\tplt.setp(leg.get_title(),fontsize=9) + \\tax2 = ax1.twinx() + \\tax2.plot([row[0] for row in dat], [row[4] for row in dat],color='$$opts{id2col}[1]') + \\tax2.plot([row[0] for row in dat], [row[5] for row in dat],color='$$opts{id2col}[0]') + \\tax2.plot([row[0] for row in dat], [row[6] for row in dat],color='k') + \\tax2.set_ylabel('Number of genotypes') + \\tax2.set_yscale('log') + \\tif af_xlog: ax1.set_xscale('log') + \\tif af_xlog: ax2.set_xscale('log') + \\tplt.subplots_adjust(left=0.15,right=0.83,bottom=0.11) + \\tplt.savefig('$img.png') + \\tif pdf_plots: plt.savefig('$img.pdf') + \\tplt.close() + + if plot_r2_by_af and len(dat)>1: + \\tfig = plt.figure(figsize=($$opts{img_width}*1.3,$$opts{img_height})) + \\tax1 = fig.add_subplot(111) + \\tax2 = ax1.twinx() + \\tax1.set_zorder(ax2.get_zorder()+1) + \\tax1.patch.set_visible(False) + \\tax2.plot([row[0] for row in dat], [row[8] for row in dat], '-o', color='r',mec='r',markersize=3) + \\tax1.plot([row[0] for row in dat], [row[7] for row in dat], '-^', color='k',markersize=3) + \\tfor tl in ax2.get_yticklabels(): tl.set_color('r') + \\tax2.set_ylabel('Number of genotypes', color='r') + \\tax2.set_yscale('log') + \\tif af_xlog: ax1.set_xscale('log') + \\tif af_xlog: ax2.set_xscale('log') + \\tax1.set_ylabel('Aggregate allelic R\$^2\$', color='k') + \\tax1.set_xlabel('Non-ref allele frequency') + \\tplt.subplots_adjust(left=0.19,right=0.83,bottom=0.11) + \\tplt.savefig('$img2.png') + \\tif pdf_plots: plt.savefig('$img2.pdf') + \\tplt.close() + + "; +} + +sub plot_concordance_by_sample +{ + my ($opts) = @_; + my @vals = get_values($opts,2,'GCsS'); + if ( !@vals ) { return; } + + my $fh = $$opts{plt_fh}; + my $img = "gts_by_sample"; + + open(my $tfh,'>',"$img.dat") or error("$img.dat: $!"); + print $tfh "# [1]Sample ID\t[2]Discordance\t[3]Sample Name\n"; + for (my $i=0; $i<@vals; $i++) + { + printf $tfh "%d\t%f\t%s\n", $i, $vals[$i][1], $vals[$i][0]; + } + close($tfh); + + tprint $fh, " + + dat = [] + with open('$img.dat', 'rb') as f: + \\treader = csv.reader(f, 'tab') + \\tfor row in reader: + \\t\\tif row[0][0] != '#': dat.append(row) + + if plot_discordance_by_sample: + \\tfig = plt.figure(figsize=(2*$$opts{img_width},$$opts{img_height}*0.7)) + \\tax1 = fig.add_subplot(111) + \\tax1.plot([row[0] for row in dat], [row[1] for row in dat],'.',color='orange') + \\tax1.set_ylabel('Non-ref discordance') + \\tax1.set_ylim(0,) + \\tif sample_names: + \\t\\t plt.xticks([int(row[0]) for row in dat],[row[2] for row in dat],**sample_font) + \\t\\t plt.subplots_adjust(**sample_margins) + \\telse: + \\t\\t plt.subplots_adjust(right=0.98,left=0.07,bottom=0.17) + \\t\\t ax1.set_xlabel('Sample ID') + \\tplt.savefig('$img.png') + \\tif pdf_plots: plt.savefig('$img.pdf') + \\tplt.close() + + + "; +} + +sub plot_counts_by_AF +{ + my ($opts) = @_; + plot_counts_by_AF_col($opts,1,'SNP'); + plot_counts_by_AF_col($opts,4,'Indel'); +} + +sub plot_counts_by_AF_col +{ + my ($opts,$col,$title) = @_; + + my $fh = $$opts{plt_fh}; + my $img = "counts_by_af.".lc($title)."s"; + + open(my $tfh,'>',"$img.dat") or error("$img.dat: $!"); + print $tfh "# [1]id\t[2]Nonref Allele Frequency\t[3]Number of sites\n"; + for my $id (file_ids($opts)) + { + my @tmp = get_values($opts,$id,'AF'); + my $vals = rebin_values(\@tmp,1,0); + for my $val (@$vals) + { + if ( !$$val[$col] ) { next; } + print $tfh "$id\t$$val[0]\t$$val[$col]\n"; + } + } + close($tfh); + + tprint $fh, " + + dat = {} + with open('$img.dat', 'rb') as f: + \\treader = csv.reader(f, 'tab') + \\tfor row in reader: + \\t\\tif row[0][0] == '#': continue + \\t\\tid = int(row[0]) + \\t\\tif id not in dat: dat[id] = [] + \\t\\tdat[id].append([float(row[1]),float(row[2])]) + + if plot_${title}_count_by_af: + \\tfig = plt.figure(figsize=(2*$$opts{img_width},$$opts{img_height}*0.7)) + \\tax1 = fig.add_subplot(111) + \\tax1.set_ylabel('Number of sites') + \\tax1.ticklabel_format(style='sci', scilimits=(0,0), axis='y') + \\tax1.set_yscale('log') + \\tif af_xlog: ax1.set_xscale('log') + \\tax1.set_xlabel('Non-reference allele frequency') + \\tax1.set_xlim(-0.05,1.05) + \\thas_data = 0 + "; + for my $id (file_ids($opts)) + { + tprint $fh, " + \\tif $id in dat and len(dat[$id])>2: + \\t\\tax1.plot([row[0] for row in dat[$id]], [row[1] for row in dat[$id]], '-o',markersize=3, color='$$opts{id2col}[$id]',mec='$$opts{id2col}[$id]',label='$$opts{title}{$id}') + \\t\\thas_data = 1 + "; + } + tprint $fh, " + \\tif has_data: + \\t\\tax1.legend(numpoints=1,markerscale=1,loc='best',prop={'size':10},frameon=False) + \\t\\tplt.title('$title count by AF') + \\t\\tplt.subplots_adjust(bottom=0.2,left=0.1,right=0.95) + \\t\\tplt.savefig('$img.png') + \\t\\tif pdf_plots: plt.savefig('$img.pdf') + \\t\\tplt.close() + + + "; +} + +sub plot_overlap_by_AF +{ + my ($opts) = @_; + plot_overlap_by_AF_col($opts,1,'SNP'); + plot_overlap_by_AF_col($opts,4,'Indel'); +} + +sub plot_overlap_by_AF_col +{ + my ($opts,$col,$title) = @_; + + my @ids = file_ids($opts); + if ( @ids != 3 ) { return; } + + my ($ia,$ib,$iab); + for (my $i=0; $i<@ids; $i++) + { + if ( @{$$opts{dat}{ID}{$ids[$i]}[0]}>1 ) { $iab = $i; next; } + if ( !defined $ia ) { $ia = $i; next; } + $ib = $i; + } + + my $fh = $$opts{plt_fh}; + my $img = "overlap_by_af.".lc($title)."s"; + my @has_vals; + + my @vals_a = get_values($opts,$ia,'AF'); + my @vals_b = get_values($opts,$ib,'AF'); + my @vals_ab = get_values($opts,$iab,'AF'); + + my (%afs,%af_a,%af_ab); + for my $val (@vals_a) { $afs{$$val[0]} = $$val[$col]; $af_a{$$val[0]} = $$val[$col]; } + for my $val (@vals_ab) { $afs{$$val[0]} = $$val[$col]; $af_ab{$$val[0]} = $$val[$col]; } + + open(my $tfh,'>',"$img.dat") or error("$img.dat: $!"); + print $tfh "# [1]Allele frequency\t[2]Fraction of sites from $$opts{title}{$ids[$ia]} also in $$opts{title}{$ids[$ib]}\t[3]Number of sites\n"; + for my $af (sort { $a<=>$b } keys %afs) + { + my $a = exists($af_a{$af}) ? $af_a{$af} : 0; + my $ab = exists($af_ab{$af}) ? $af_ab{$af} : 0; + my $yval = ($a+$ab) ? $ab * 100. / ($a + $ab) : 0; + print $tfh "$af\t$yval\t" .($a+$ab). "\n"; + } + close($tfh) or error("close $img.dat"); + + tprint $fh, " + + dat = [] + + with open('$img.dat', 'rb') as f: + \\treader = csv.reader(f, 'tab') + \\tfor row in reader: + \\t\\tif row[0][0] != '#': dat.append(row) + + if plot_${title}_overlap_by_af and len(dat)>1: + \\tfig = plt.figure(figsize=(2*$$opts{img_width},$$opts{img_height}*0.7)) + \\tax1 = fig.add_subplot(111) + \\tax1.plot([row[0] for row in dat], [row[1] for row in dat],'-o',markersize=3, color='$$opts{id2col}[1]',mec='$$opts{id2col}[1]') + \\tax1.set_ylabel('Fraction found in $$opts{title}{$ib} [%]') + \\tax1.set_xscale('log') + \\tax1.set_xlabel('Non-reference allele frequency in $$opts{title}{$ia}') + \\tax1.set_xlim(0,1.01) + \\tplt.title('$title overlap by AF') + \\tplt.subplots_adjust(bottom=0.2,left=0.1,right=0.95) + \\tplt.savefig('$img.png') + \\tif pdf_plots: plt.savefig('$img.pdf') + \\tplt.close() + "; +} + +sub plot_indel_distribution +{ + my ($opts,$id) = @_; + + my @vals = get_values($opts,$id,'IDD'); + if ( !@vals ) { return; } + + # Set xlim to show 99 of indels but ignore outliers + my @tmp; + for my $id (file_ids($opts)) + { + my @v = get_values($opts,$id,'IDD'); + for my $v (@v) { $tmp[ abs($$v[0]) ] += $$v[1]; } + } + my $n; + for my $t (@tmp) { $n += $t ? $t : 0; } + my ($sum,$xlim); + for ($xlim=0; $xlim<@tmp; $xlim++) + { + $sum += $tmp[$xlim] ? $tmp[$xlim] : 0; + if ( $sum/$n >= 0.99 ) { last; } + } + if ( $xlim<20 ) { $xlim=20; } + + my $fh = $$opts{plt_fh}; + my $img = "indels.$id"; + + + open(my $tfh,'>',"$img.dat") or error("$img.dat: $!"); + print $tfh "# [1]Indel length\t[2]Count\n"; + for my $val (@vals) { print $tfh "$$val[0]\t$$val[1]\n"; } + close($tfh); + + tprint $fh, " + + dat = [] + with open('$img.dat', 'rb') as f: + \\treader = csv.reader(f, 'tab') + \\tfor row in reader: + \\t\\tif row[0][0] != '#': dat.append([float(x) for x in row]) + + if plot_indel_dist and len(dat)>0: + \\tfig = plt.figure(figsize=($$opts{img_width},$$opts{img_height})) + \\tax1 = fig.add_subplot(111) + \\tax1.bar([row[0]-0.5 for row in dat], [row[1] for row in dat], color='$$opts{id2col}[0]')# , edgecolor='$$opts{id2col}[0]') + \\tax1.set_xlabel('InDel Length') + \\tax1.set_ylabel('Count') + \\tax1.ticklabel_format(style='sci', scilimits=(0,0), axis='y') + \\tax1.set_xlim(-$xlim,$xlim) + \\tplt.subplots_adjust(bottom=0.17) + \\tplt.title('$$opts{title}{$id}') + \\tplt.savefig('$img.png') + \\tif pdf_plots: plt.savefig('$img.pdf') + \\tplt.close() + "; +} + +sub plot_substitutions +{ + my ($opts,$id) = @_; + + my @vals = get_values($opts,$id,'ST'); + if ( !@vals ) { return; } + + my $fh = $$opts{plt_fh}; + my $img = "substitutions.$id"; + + tprint $fh, " + dat = [ + "; + for (my $i=0; $i<@vals; $i++) { my $val=$vals[$i]; tprint $fh, "\t[$i,'$$val[0]',$$val[1]],\n"; } + tprint $fh, "] + + if plot_substitutions: + \\tfig = plt.figure(figsize=($$opts{img_width},$$opts{img_height})) + \\tcm = mpl.cm.get_cmap('autumn') + \\tn = 12 + \\tcol = range(n) + \\tfor i in range(n): col[i] = cm(1.*i/n) + \\tax1 = fig.add_subplot(111) + \\tax1.bar([row[0] for row in dat], [row[2] for row in dat], color=col) + \\tax1.set_ylabel('Count') + \\tax1.ticklabel_format(style='sci', scilimits=(0,0), axis='y') + \\tax1.set_xlim(-0.5,n+0.5) + \\tplt.xticks([row[0] for row in dat],[row[1] for row in dat],rotation=45) + \\tplt.title('$$opts{title}{$id}') + \\tplt.savefig('$img.png') + \\tif pdf_plots: plt.savefig('$img.pdf') + \\tplt.close() + + "; +} + +sub singletons +{ + my ($opts,$id) = @_; + my @si_vals = get_values($opts,$id,'SiS'); + my $si_snps = $si_vals[0][1]; + my $si_indels = $si_vals[0][4]; + my $si_irc = sprintf "%.3f", $si_vals[0][6] ? $si_vals[0][5]/($si_vals[0][5]+$si_vals[0][6]) : 0; + my $si_tstv = sprintf "%.2f", $si_vals[0][3] ? $si_vals[0][2]/$si_vals[0][3] : 0; + my @all_vals = get_values($opts,$id,'AF'); + my $nsnps = 0; + my $nindels = 0; + for my $val (@all_vals) + { + $nsnps += $$val[1]; + $nindels += $$val[4]; + } + $si_snps = sprintf "%.1f", $nsnps ? $si_snps*100./$nsnps : 0; + $si_indels = sprintf "%.1f", $nindels ? $si_indels*100./$nindels : 0; + return { snps=>$si_snps, indels=>$si_indels, tstv=>$si_tstv, irc=>$si_irc }; +} + +sub calc_3n_n3n +{ + my (@vals) = @_; + my $n3 = 0; + my $nn3 = 0; + for my $val (@vals) + { + if ( !($$val[0]%3) ) { $n3++; } + else { $nn3++; } + } + if ( !$nn3 ) { return '-'; } + return sprintf("%.2f", $n3/$nn3); +} + +sub fmt_slide3v +{ + my ($opts, $image, $title) = @_; + + my $n = 0; + for my $id (0..2) + { + if ( -e "$image.$id.$$opts{fmt}" ) { $n++; } + } + if ( !$n ) { return ''; } + my $h = $$opts{tex}{slide3v}{"height$n"}; + my $slide = q[\vbox{]; + for my $id (0..2) + { + if ( !-e "$image.$id.$$opts{fmt}" ) { next; } + $slide .= qq[\\centerline{\\includegraphics[$$opts{ext},height=$h]{$image.$id}}]; + } + $slide .= '}'; + return qq[ + % $title + % + \\hslide{$title}{$slide} + ]; +} + +sub fmt_slide3h +{ + my ($opts, $image, $title) = @_; + my $n = 0; + for my $id (0..2) + { + if ( -e "$image.$id.$$opts{fmt}" ) { $n++; } + } + if ( !$n ) { return ''; } + my $w = $$opts{tex}{slide3h}{"width$n"}; + my $slide = ''; + for my $id (0..2) + { + if ( !-e "$image.$id.$$opts{fmt}" ) { next; } + $slide .= qq[\\includegraphics[$$opts{ext},width=$w]{$image.$id}]; + } + return qq[ + % $title + % + \\hslide{$title}{$slide} + ]; +} + +sub bignum +{ + my ($num) = @_; + if ( !defined $num ) { return ''; } + if ( !($num=~/^\d+$/) ) { return $num; } + my $len = length($num); + my $out; + for (my $i=0; $i<$len; $i++) + { + $out .= substr($num,$i,1); + if ( $i+1<$len && !(($len-$i-1)%3) ) { $out .= ','; } + } + return $out; +} + +sub create_pdf +{ + my ($opts) = @_; + + chdir($$opts{dir}); + + my @ids = file_ids($opts); + my $width = "25.4cm"; # todo: move all this to $$opts{tex} + my $height = "19cm"; + my $height1 = "13cm"; + my $width1 = "23cm"; + my $width2 = @ids==3 ? "10.5cm" : "10.5cm"; + my $width3 = @ids==3 ? "8cm" : "15cm"; + my $fmt = $$opts{rasterize} ? 'png' : 'pdf'; + my $ext = "type=$fmt,ext=.$fmt,read=.$fmt"; + my $args = { ext=>$ext, width3=>$width3, n=>scalar @ids }; + $$opts{fmt} = $fmt; + $$opts{ext} = $ext; + + # Check that xcolor is available + my @has_xcolor = `kpsewhich xcolor.sty`; + if ( !@has_xcolor ) + { + warn("Note: The xcolor.sty package not available, black and white tables only...\n\n"); + } + + my $tex_file = "summary.tex"; + my $pdf_file = "summary.pdf"; + open(my $tex,'>',$tex_file) or error("$tex_file: $!"); + tprint $tex, qq[ + % This file was produced by plot-vcfstats, the command line was: + % $$opts{args} + % + % Edit as necessary and recreate the PDF by running + % pdflatex $tex_file + % + + % Slides style and dimensions + % + \\nonstopmode + \\documentclass[17pt]{memoir} + \\setstocksize{$height}{$width} + \\settrimmedsize{\\stockheight}{\\stockwidth}{*} + \\settrims{0pt}{0pt} + \\setlrmarginsandblock{1cm}{*}{*} + \\setulmarginsandblock{1.5cm}{*}{*} + \\setheadfoot{1mm}{1cm} + \\setlength{\\parskip}{0pt} + \\setheaderspaces{*}{1mm}{*} + \\setmarginnotes{1mm}{1mm}{1mm} + \\checkandfixthelayout[fixed] + \\usepackage{charter} % font + \\pagestyle{plain} + \\makeevenfoot{plain}{}{}{\\thepage} + \\makeoddfoot{plain}{}{}{\\thepage} + \\usepackage{graphicx} + + % For colored tables. If xcolor.sty is not available on your system, + % download xcolor.sty.gz LaTeX class style from + % http://www.ukern.de/tex/xcolor.html + % Unpack and install system-wide or place elsewhere and make available by + % setting the TEXINPUTS environment variable (note the colon) + % export TEXINPUTS=some/dir: + % The list of the recognised path can be obtained by running `kpsepath tex` + % + \\usepackage{multirow} + \\setlength{\\tabcolsep}{0.6em} + \\renewcommand{\\arraystretch}{1.2} + ]; + if ( @has_xcolor ) + { + tprint $tex, '\usepackage[table]{xcolor}'; + } + else + { + tprint $tex, qq[ + \\newcommand{\\definecolor}[3]{} + \\newcommand{\\columncolor}[1]{} + \\newcommand{\\rowcolors}[4]{} + \\newcommand{\\arrayrulecolor}[1]{} + ]; + } + tprint $tex, qq[ + \\definecolor{hcol1}{rgb}{1,0.6,0} + \\definecolor{hcol2}{rgb}{1,0.68,0.2} + \\definecolor{row1}{rgb}{1,0.88,0.7} + \\definecolor{row2}{rgb}{1,0.92,0.8} % #FFEBCC + \\setlength{\\arrayrulewidth}{1.5pt} + + % Slide headings + \\newcommand*{\\head}[1]{{\\Large\\centerline{#1}\\vskip0.5em}} + + % Slide definition + \\newcommand*{\\hslide}[2]{% + \\head{#1}% + \\begin{vplace}[0.5]\\centerline{#2}\\end{vplace}\\newpage} + \\newcommand{\\pdf}[2]{\\IfFileExists{#2.$fmt}{\\includegraphics[#1]{#2}}{}} + + + % The actual slides + \\begin{document} + ]; + + + # Table with summary numbers + my $slide .= q[ + \begin{minipage}{\textwidth}\centering + \small \rowcolors*{3}{row2}{row1} \arrayrulecolor{black} + \begin{tabular}{l | r r r | r r | r | r} + \multicolumn{1}{>{\columncolor{hcol1}}l|}{} + & \multicolumn{3}{>{\columncolor{hcol1}}c|}{SNPs} + & \multicolumn{2}{>{\columncolor{hcol1}}c|}{indels} + & \multicolumn{1}{>{\columncolor{hcol1}}c|}{MNPs} + & \multicolumn{1}{>{\columncolor{hcol1}}c}{others} \\\\ + % + \multicolumn{1}{>{\columncolor{hcol2}}l|}{Callset} + & \multicolumn{1}{>{\columncolor{hcol2}}c}{n} + & \multicolumn{1}{>{\columncolor{hcol2}}c }{ts/tv} + & \multicolumn{1}{>{\columncolor{hcol2}}c|}{\\footnotesize(1st ALT)} + & \multicolumn{1}{>{\columncolor{hcol2}}c}{n} + & \multicolumn{1}{>{\columncolor{hcol2}}c}{frm$^*$} + & \multicolumn{1}{>{\columncolor{hcol2}}c|}{} + & \multicolumn{1}{>{\columncolor{hcol2}}c}{} \\\\ \hline + ]; + my %tex_titles; + for my $id (@ids) + { + my $snps = get_value($opts,$id,'number of SNPs:'); + my $indels = get_value($opts,$id,'number of indels:'); + my $mnps = get_value($opts,$id,'number of MNPs:'); + my $others = get_value($opts,$id,'number of others:'); + my $tstv = sprintf "%.2f",get_values($opts,$id,'TSTV',0,2); + my $tstv1 = sprintf "%.2f",get_values($opts,$id,'TSTV',0,5); + my @frsh = get_values($opts,$id,'FS'); + my $frsh = @frsh ? $frsh[0][3] : '--'; + my @rc = get_values($opts,$id,'ICS'); + my $title = $$opts{title}{$id}; + $title =~ s/_/\\_/g; + $title =~ s/^\s*\*/\$*\$/; # leading asterisks is eaten by TeX + $tex_titles{$id} = $title; + $slide .= qq[ $title & ] . bignum($snps) . qq[ & $tstv & $tstv1 & ] . bignum($indels) . qq[ & $frsh & ] . bignum($mnps) . ' & ' . bignum($others) . qq[ \\\\ \n]; + } + $slide .= q[% + \multicolumn{8}{r}{$^*$ frameshift ratio: out/(out+in)} \\\\ + \end{tabular} + \\\\ \vspace{1em} + \begin{tabular}{l | r r r | r r} + \multicolumn{1}{>{\columncolor{hcol1}}l|}{} + & \multicolumn{3}{>{\columncolor{hcol1}}c|}{singletons {\footnotesize(AC=1)}} + & \multicolumn{2}{>{\columncolor{hcol1}}c}{multiallelic} \\\\ + % + \multicolumn{1}{>{\columncolor{hcol2}}l|}{Callset} + & \multicolumn{1}{>{\columncolor{hcol2}}c}{SNPs} + & \multicolumn{1}{>{\columncolor{hcol2}}c}{ts/tv} + & \multicolumn{1}{>{\columncolor{hcol2}}c}{indels} + & \multicolumn{1}{>{\columncolor{hcol2}}c}{sites} + & \multicolumn{1}{>{\columncolor{hcol2}}c}{SNPs} \\\\ \hline + ]; + for my $id (@ids) + { + my $snps = get_value($opts,$id,'number of SNPs:'); + my $s = singletons($opts,$id); + my $mals = get_value($opts,$id,'number of multiallelic sites:'); + my $msnps = get_value($opts,$id,'number of multiallelic SNP sites:'); + my $title = $tex_titles{$id}; + $slide .= qq[ $title & $$s{snps}\\% & $$s{tstv} & $$s{indels}\\% & ] . bignum($mals) . ' &' . bignum($msnps) . qq[ \\\\ \n]; + } + $slide .= q[ \\end{tabular} + \\vspace{2em} + \\begin{itemize}[-] + \\setlength{\\itemsep}{0pt} + ]; + for my $id (@ids) + { + my $fname = $$opts{dat}{ID}{$id}[0][0]; + if ( $$opts{title}{$id} =~ / \+ / ) { next; } + $fname =~ s/.{80}/$&\\\\\\hskip2em /g; + $fname =~ s/_/\\_/g; + $slide .= qq[\\item $tex_titles{$id} .. \\texttt{\\footnotesize $fname}\n]; + } + $slide .= q[\\end{itemize}\\end{minipage}]; + my $title = exists($$opts{main_title}) ? $$opts{main_title} : 'Summary Numbers'; + tprint $tex, qq[ + % Table with summary numbers + % + \\hslide{$title}{$slide} + + ]; + + + # Venn bars + if ( @ids==3 ) + { + tprint $tex, qq[% + + % Venn numbers + % + \\hslide{Total counts}{% + \\includegraphics[$ext,width=$width2]{venn_bars.snps}% + \\includegraphics[$ext,width=$width2]{venn_bars.indels} + } + ]; + } + + tprint $tex, fmt_slide3v($opts, "tstv_by_sample", 'Ts/Tv by sample'); + tprint $tex, fmt_slide3v($opts, "hets_by_sample", 'Hets vs non-ref Homs by sample'); + tprint $tex, fmt_slide3v($opts, "singletons_by_sample", 'Singletons by sample {\normalsize(hets and homs)}'); + tprint $tex, fmt_slide3v($opts, "dp_by_sample", 'Average depth by sample'); + tprint $tex, fmt_slide3v($opts, "snps_by_sample", 'Number of SNPs by sample'); + tprint $tex, fmt_slide3v($opts, "indels_by_sample", 'Number of indels by sample'); + if ( scalar get_values($opts,2,'GCsS') ) + { + tprint $tex, qq[ + % Genotype discordance by sample + % + \\hslide{Genotype discordance by sample}{\\pdf{$ext,width=$width1}{gts_by_sample}} + + ]; + } + if ( scalar get_values($opts,2,'GCsAF') ) + { + my @vals = get_values($opts,2,'NRDs'); + my $nrd = sprintf "%.2f", $vals[0][0]; + my $rr = sprintf "%.2f", $vals[0][1]; + my $ra = sprintf "%.2f", $vals[0][2]; + my $aa = sprintf "%.2f", $vals[0][3]; + my $nsamples = get_value($opts,2,'number of samples:'); + my $table = qq[% + {\\small + \\rowcolors*{1}{row2}{row1}\\arrayrulecolor{black} + \\begin{tabular}{c | c | c | c } + \\multicolumn{1}{>{\\columncolor{hcol1}}c|}{REF/REF} & + \\multicolumn{1}{>{\\columncolor{hcol1}}c|}{REF/ALT} & + \\multicolumn{1}{>{\\columncolor{hcol1}}c|}{ALT/ALT} & + \\multicolumn{1}{>{\\columncolor{hcol1}}c}{NRDs} \\\\ \\hline + $rr\\% & $ra\\% & $aa\\% & $nrd\\% \\\\ + \\end{tabular}}]; + tprint $tex, qq[ + % Genotype discordance by AF + % + \\head{Genotype discordance by AF}\\begin{vplace}[0.7]\\centerline{$table}% + \\centerline{\\pdf{$ext,height=$height1}{gts_by_af}}\\end{vplace} + \\newpage + + % dosage r2 by AF + % + \\hslide{Allelic R\$^2\$ by AF}{\\pdf{$ext,height=$height1}{r2_by_af}} + ]; + } + if ( -e "counts_by_af.snps.$fmt" && -e "counts_by_af.indels.$fmt" ) + { + tprint $tex, qq[ + % SNP and indel counts by AF + % + \\hslide{}{\\vbox{\\noindent\\includegraphics[$ext,width=$width1]{counts_by_af.snps}\\\\% + \\noindent\\includegraphics[$ext,width=$width1]{counts_by_af.indels}}} + ]; + } + if ( -e "overlap_by_af.snps.$fmt" && -e "overlap_by_af.indels.$fmt" ) + { + tprint $tex, qq[ + % SNP and indel overlap by AF + % + \\hslide{}{\\vbox{\\noindent\\includegraphics[$ext,width=$width1]{overlap_by_af.snps}\\\\% + \\noindent\\includegraphics[$ext,width=$width1]{overlap_by_af.indels}}} + ]; + } + tprint $tex, fmt_slide3h($opts, "tstv_by_af", 'Ts/Tv by AF'); + tprint $tex, fmt_slide3h($opts, "tstv_by_qual", 'Ts/Tv stratified by QUAL'); + tprint $tex, fmt_slide3h($opts, "indels", 'Indel distribution'); + tprint $tex, fmt_slide3h($opts, "depth", 'Depth distribution'); + tprint $tex, fmt_slide3h($opts, "hwe", 'Number of HETs by AF'); + tprint $tex, fmt_slide3h($opts, "substitutions", 'Substitution types'); + #tprint $tex, fmt_slide3h($opts, "irc_by_af", 'Indel Repeat Consistency by AF'); + #tprint $tex, fmt_slide3h($opts, "irc_by_rlen", 'Indel Consistency by Repeat Type'); + + tprint $tex, "\n\n\\end{document}\n"; + close($tex); + + $tex_file =~ s{^.+/}{}; + my $cmd = "pdflatex $tex_file >$$opts{logfile} 2>&1"; + print STDERR "Creating PDF: $cmd\n" unless !$$opts{verbose}; + system($cmd); + if ( $? ) { error("The command exited with non-zero status, please consult the output of pdflatex: $$opts{dir}$$opts{logfile}\n\n"); } + print STDERR "Finished: $$opts{dir}/$pdf_file\n" unless !$$opts{verbose}; +} + +sub merge_vcfstats +{ + my ($opts) = @_; + + my $fh = *STDOUT; + if ( !$$opts{merge} ) + { + open($fh,'>',"merge.chk") or error("merge.chk: $!\n"); + } + + print $fh "# This file was produced by plot-vcfstats, the command line was:\n# $$opts{args}\n#\n"; + + for my $sec (@{$$opts{sections}}) + { + my $sid = $$sec{id}; + if ( !exists($$opts{dat}{$sid}) ) { next; } + + print $fh "# $$sec{header}\n$$sec{exp}\n"; + for my $id (sort keys %{$$opts{dat}{$sid}}) + { + for my $rec (@{$$opts{dat}{$sid}{$id}}) + { + print $fh "$sid\t$id\t", join("\t",@$rec), "\n"; + } + } + + if ( $sid eq 'ID' ) + { + print $fh "# $$opts{id2sec}{SN}{header}\n$$opts{id2sec}{SN}{exp}\n"; + # output summary numbers here + for my $id (keys %{$$opts{dat}}) + { + if ( exists($$opts{exp}{$id}) ) { next; } + for my $key (@{$$opts{SN_keys}}) + { + next unless exists $$opts{dat}{$id}{$key}; + print $fh "SN\t$id\t$key\t$$opts{dat}{$id}{$key}\n"; + } + } + } + } +} + diff --git a/misc/run-roh.pl b/misc/run-roh.pl new file mode 100755 index 0000000..4a1afa4 --- /dev/null +++ b/misc/run-roh.pl @@ -0,0 +1,308 @@ +#!/usr/bin/env perl +# +# Author: petr.danecek@sanger +# + +use strict; +use warnings; +use Carp; +use Data::Dumper; + +my $opts = parse_params(); +run_roh($opts); +eval_roh($opts); + +exit; + +#-------------------------------- + +sub error +{ + my (@msg) = @_; + if ( scalar @msg ) { confess @msg,"\n"; } + print + "About: This is a convenience wrapper for \"bcftools roh\" which takes multiple VCF/BCF files\n", + " and locates regions private to a sample or shared across multiple samples. On input it\n", + " expects a directory with .vcf, .vcf.gz or .bcf files, a file with allele frequencies\n", + " and a genetic map. See http://samtools.github.io/bcftools/howtos/roh-calling.html for\n", + " details\n", + "Usage: run-roh.pl [OPTIONS]\n", + "Options:\n", + " -a, --af-annots Allele frequency annotations [1000GP-AFs/AFs.tab.gz]\n", + " -i, --indir Input directory with VCF files\n", + " -l, --min-length Filter input regions shorter than this [1e6]\n", + " -m, --genmap Directory with genetic map in IMPUTE2 format (optional)\n", + " -M, --rec-rate constant recombination rate per bp (optional)\n", + " -n, --min-markers Filter input regions with fewer marker than this [100]\n", + " -o, --outdir Output directory\n", + " -q, --min-qual Filter input regions with quality smaller than this [10]\n", + " -s, --silent Quiet output, do not print commands\n", + " -h, -?, --help This help message\n", + "\n"; + exit -1; +} +sub parse_params +{ + my $opts = + { + af_annots => '1000GP-AFs/AFs.tab.gz', + verbose => 1, + min_length => 1e6, + min_markers => 100, + min_qual => 10, + }; + while (defined(my $arg=shift(@ARGV))) + { + if ( $arg eq '-q' || $arg eq '--min-qual' ) { $$opts{min_qual}=shift(@ARGV); next } + if ( $arg eq '-l' || $arg eq '--min-length' ) { $$opts{min_length}=shift(@ARGV); next } + if ( $arg eq '-n' || $arg eq '--min-markers' ) { $$opts{min_markers}=shift(@ARGV); next } + if ( $arg eq '-s' || $arg eq '--silent' ) { $$opts{verbose}=0; next } + if ( $arg eq '-a' || $arg eq '--af-annots' ) { $$opts{af_annots}=shift(@ARGV); next } + if ( $arg eq '-m' || $arg eq '--genmap' ) { $$opts{genmap}=shift(@ARGV); next } + if ( $arg eq '-M' || $arg eq '--rec-rate' ) { $$opts{rec_rate}=shift(@ARGV); next } + if ( $arg eq '-o' || $arg eq '--outdir' ) { $$opts{outdir}=shift(@ARGV); next } + if ( $arg eq '-i' || $arg eq '--indir' ) { $$opts{indir}=shift(@ARGV); next } + if ( $arg eq '-?' || $arg eq '-h' || $arg eq '--help' ) { error(); } + error("Unknown parameter \"$arg\". Run -h for help.\n"); + } + if ( !exists($$opts{outdir}) ) { error("Missing the -o, --outdir option.\n") } + if ( !exists($$opts{indir}) ) { error("Missing the -i, --indir option.\n") } + if ( ! -e $$opts{af_annots} ) { error("The annotation file does not exist: $$opts{af_annots}\n"); } + if ( ! -e "$$opts{af_annots}.tbi" ) { error("The annotation file is not indexed: $$opts{af_annots}.tbi\n"); } + if ( ! -e "$$opts{af_annots}.hdr" ) { error("The annotation file has no header: $$opts{af_annots}.hdr\n"); } + if ( exists($$opts{genmap}) && ! -d "$$opts{genmap}" ) { error("The directory with genetic maps does not exist: $$opts{genmap}\n"); } + return $opts; +} + +sub cmd +{ + my ($cmd,%args) = @_; + + if ( $args{verbose} ) { print STDERR $cmd,"\n"; } + + # Why not to use backticks? Perl calls /bin/sh, which is often bash. To get the correct + # status of failing pipes, it must be called with the pipefail option. + + my $kid_io; + my $pid = open($kid_io, "-|"); + if ( !defined $pid ) { error("Cannot fork: $!"); } + + my @out; + if ($pid) + { + # parent + @out = <$kid_io>; + close($kid_io); + } + else + { + # child + exec('/bin/bash', '-o','pipefail','-c', $cmd) or error("Failed to run the command [/bin/sh -o pipefail -c $cmd]: $!"); + } + + if ( exists($args{exit_on_error}) && !$args{exit_on_error} ) { return @out; } + + my $exit_status = $?; + my $status = exists($args{require_status}) ? $args{require_status} : 0; + if ( $status ne $exit_status ) + { + my $msg; + if ( $? & 0xff ) + { + $msg = "The command died with signal ".($? & 0xff); + } + else + { + $msg = "The command exited with status ".($? >> 8)." (expected $status)"; + } + $msg .= ":\n\t$cmd\n\n"; + if ( @out ) { $msg .= join('',@out,"\n\n"); } + error($msg); + } + return @out; +} + +# determine the common prefix/suffix in file names like: +# genetic_map_chr12_combined_b37.txt +# genetic_map_chr13_combined_b37.txt +sub parse_genmap_path +{ + my ($opts) = @_; + if ( !exists($$opts{genmap}) or !-d $$opts{genmap} ) { return ''; } + my @files = glob("$$opts{genmap}/*"); + my $prefix = $files[0]; + my $suffix = $files[0]; + for my $file (@files) + { + while ( length($prefix) && index($file,$prefix)==-1 ) + { + substr($prefix,length($prefix)-1,1,''); + } + if ( !length($prefix) ) { last; } + } + for my $file (@files) + { + while ( length($suffix) && rindex($file,$suffix)==-1 ) + { + substr($suffix,0,1,''); + } + if ( !length($suffix) ) { last; } + } + my @test = glob("$prefix*$suffix"); + if ( @test != @files ) + { + print STDERR "Warning: Could not determine the genetic map files [$prefix][$suffix]\n"; + return ''; + } + return "-m $prefix\{CHROM}$suffix"; +} + +sub run_roh +{ + my ($opts) = @_; + cmd("mkdir -p $$opts{outdir}",%$opts) unless -d $$opts{outdir}; + + my $chr_fname = "$$opts{outdir}/chr-names.txt"; + open(my $fh,'>',$chr_fname) or error("$chr_fname: $!"); + for my $chr (1..22,'X') { print $fh "chr$chr\t$chr\n"; } + close($fh) or error("close failed: $chr_fname"); + + my @files = (); + opendir(my $dh,$$opts{indir}) or error("$$opts{indir}: $!"); + while (my $file = readdir($dh)) + { + if ( !($file=~/\.vcf$/i) && !($file=~/\.vcf\.gz$/i) && !($file=~/\.bcf$/i) ) { next; } + my $outfile = "$$opts{outdir}/$`.bcf"; + push @files,$outfile; + if ( -e $outfile ) { next; } + cmd( + "bcftools annotate --rename-chrs $chr_fname $$opts{indir}/$file -Ou | " . + "bcftools annotate -c CHROM,POS,REF,ALT,AF1KG -h $$opts{af_annots}.hdr -a $$opts{af_annots} -Ob -o $outfile.part && " . + "mv $outfile.part $outfile",%$opts); + } + closedir($dh) or error("close failed: $$opts{indir}"); + + my $genmap = parse_genmap_path($opts); + if ( exists($$opts{rec_rate}) ) { $genmap .= " -M $$opts{rec_rate}"; } + + for my $file (@files) + { + if ( -e "$file.txt.gz" ) { next; } + my @out = cmd("bcftools roh --AF-tag AF1KG $genmap $file -Orz -o $file.txt.gz.part 2>&1 | tee -a $file.log",%$opts); + for my $line (@out) + { + if ( !($line=~m{total/processed:\s+(\d+)/(\d+)}) ) { next; } + my $total = $1; + my $used = $2; + if ( !$total or $used/$total < 0.3 ) + { + print STDERR @out; + print STDERR "WARNING: Less than 30% of sites was used!\n\n"; + } + } + cmd(qq[bcftools query -f'GT\\t%CHROM\\t%POS[\\t%SAMPLE\\t%GT]\\n' $file | gzip -c >> $file.txt.gz.part && mv $file.txt.gz.part $file.txt.gz],%$opts); + } + $$opts{files} = \@files; +} + +sub next_region +{ + my ($regions) = @_; + my $chr = undef; + for my $chrom (sort keys %$regions) + { + if ( %{$$regions{$chrom}} ) { $chr = $chrom; last; } + delete($$regions{$chrom}); + } + if ( !defined $chr ) { return undef; } + + my %min = (); + for my $smpl (keys %{$$regions{$chr}}) + { + if ( !exists($$regions{$chr}{$smpl}) ) { next; } + my $reg = $$regions{$chr}{$smpl}[0]; + if ( !%min ) + { + $min{chr} = $chr; + $min{beg} = $$reg{beg}; + $min{end} = $$reg{end}; + next; + } + if ( $min{beg} > $$reg{beg} ) { $min{beg} = $$reg{beg}; } + } + if ( !%min ) { return undef; } + for my $smpl (keys %{$$regions{$chr}}) + { + if ( !exists($$regions{$chr}{$smpl}) ) { next; } + my $reg = $$regions{$chr}{$smpl}[0]; + if ( $min{end} > $$reg{end} ) { $min{end} = $$reg{end}; } + if ( $min{end} > $$reg{beg} - 1 && $min{beg} != $$reg{beg} ) { $min{end} = $$reg{beg} - 1; } + } + return \%min; +} + +sub eval_roh +{ + my ($opts) = @_; + my %regions = (); + my %samples = (); + my %lengths = (); + for my $file (@{$$opts{files}}) + { + open(my $fh,"gunzip -c $file.txt.gz |") or error("gunzip -c $file.txt.gz: $!"); + while (my $line=<$fh>) + { + if ( !($line=~/^RG/) ) { next; } + my (%vals); + @vals{qw(type smpl chr beg end len num qual)} = split(/\s+/,$line); + if ( $vals{type} ne 'RG' ) { next; } + chomp($vals{qual}); + if ( $vals{len} < $$opts{min_length} ) { next; } + if ( $vals{num} < $$opts{min_markers} ) { next; } + if ( $vals{qual} < $$opts{min_qual} ) { next; } + push @{$regions{$vals{chr}}{$vals{smpl}}},\%vals; + $samples{$vals{smpl}} = 1; + $lengths{$vals{smpl}} += $vals{end} - $vals{beg} + 1; + } + close($fh) or error("close failed: gunzip -c $file.txt.gz"); + } + open(my $fh,'>',"$$opts{outdir}/merged.txt") or error("$$opts{outdir}/merged.txt: $!"); + my @samples = sort keys %samples; + print $fh "# [1]chrom\t[2]beg\t[3]end\t[4]length (Mb)"; + my $i = 5; + for my $smpl (@samples) { print $fh "\t[$i]$smpl"; $i++; } + print $fh "\n"; + while (my $min = next_region(\%regions)) + { + my $chr = $$min{chr}; + my $beg = $$min{beg}; + my $end = $$min{end}; + printf $fh "$chr\t$beg\t$end\t%.2f",($end-$beg+1)/1e6; + for my $smpl (@samples) + { + if ( !exists($regions{$chr}{$smpl}) ) { goto not_present; } + my $reg = $regions{$chr}{$smpl}[0]; + if ( $$reg{beg} > $end ) { goto not_present; } + if ( $$reg{end} > $end ) { $regions{$chr}{$smpl}[0]{beg} = $end + 1; } + else { shift @{$regions{$chr}{$smpl}}; } + if ( !@{$regions{$chr}{$smpl}} ) { delete($regions{$chr}{$smpl}); } + $lengths{$smpl} -= $end - $beg + 1; + print $fh "\t1"; + next; +not_present: + print $fh "\t0"; + } + print $fh "\n"; + } + close($fh) or error("close failed: $$opts{outdir}/merged.txt"); + for my $smpl (@samples) + { + if ( $lengths{$smpl}!=0 ) + { + print STDERR "ERROR: a bug detected, sanity check failed, expected zero length : $smpl .. $lengths{$smpl}\n"; + } + } + print STDERR "The merged regions are in $$opts{outdir}/merged.txt\n"; +} + + diff --git a/misc/vcfutils.pl b/misc/vcfutils.pl new file mode 100755 index 0000000..03839ae --- /dev/null +++ b/misc/vcfutils.pl @@ -0,0 +1,588 @@ +#!/usr/bin/perl -w +# +# Copyright (C) 2010 Broad Institute. +# Copyright (C) 2011, 2014 Genome Research Ltd. +# +# Author: Heng Li +# +# Permission is hereby granted, free of charge, to any person obtaining a copy +# of this software and associated documentation files (the "Software"), to deal +# in the Software without restriction, including without limitation the rights +# to use, copy, modify, merge, publish, distribute, sublicense, and/or sell +# copies of the Software, and to permit persons to whom the Software is +# furnished to do so, subject to the following conditions: +# +# The above copyright notice and this permission notice shall be included in +# all copies or substantial portions of the Software. +# +# THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +# IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +# FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL +# THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER +# LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING +# FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER +# DEALINGS IN THE SOFTWARE. + +use strict; +use warnings; +use Getopt::Std; + +&main; +exit; + +sub main { + &usage if (@ARGV < 1); + my $command = shift(@ARGV); + my %func = (subsam=>\&subsam, listsam=>\&listsam, fillac=>\&fillac, qstats=>\&qstats, varFilter=>\&varFilter, + hapmap2vcf=>\&hapmap2vcf, ucscsnp2vcf=>\&ucscsnp2vcf, filter4vcf=>\&varFilter, ldstats=>\&ldstats, + gapstats=>\&gapstats, splitchr=>\&splitchr, vcf2fq=>\&vcf2fq); + die("Unknown command \"$command\".\n") if (!defined($func{$command})); + &{$func{$command}}; +} + +sub splitchr { + my %opts = (l=>5000000); + getopts('l:', \%opts); + my $l = $opts{l}; + die(qq/Usage: vcfutils.pl splitchr [-l $opts{l}] \n/) if (@ARGV == 0 && -t STDIN); + while (<>) { + my @t = split; + my $last = 0; + for (my $i = 0; $i < $t[1];) { + my $e = ($t[1] - $i) / $l < 1.1? $t[1] : $i + $l; + print "$t[0]:".($i+1)."-$e\n"; + $i = $e; + } + } +} + +sub subsam { + die(qq/Usage: vcfutils.pl subsam [samples]\n/) if (@ARGV == 0); + my ($fh, %h); + my $fn = shift(@ARGV); + my @col; + open($fh, ($fn =~ /\.gz$/)? "gzip -dc $fn |" : $fn) || die; + $h{$_} = 1 for (@ARGV); + while (<$fh>) { + if (/^##/) { + print; + } elsif (/^#/) { + my @t = split; + my @s = @t[0..8]; # all fixed fields + FORMAT + for (9 .. $#t) { + if ($h{$t[$_]}) { + push(@s, $t[$_]); + push(@col, $_); + } + } + pop(@s) if (@s == 9); # no sample selected; remove the FORMAT field + print join("\t", @s), "\n"; + } else { + my @t = split; + if (@col == 0) { + print join("\t", @t[0..7]), "\n"; + } else { + print join("\t", @t[0..8], map {$t[$_]} @col), "\n"; + } + } + } + close($fh); +} + +sub listsam { + die(qq/Usage: vcfutils.pl listsam \n/) if (@ARGV == 0 && -t STDIN); + while (<>) { + if (/^#/ && !/^##/) { + my @t = split; + print join("\n", @t[9..$#t]), "\n"; + exit; + } + } +} + +sub fillac { + die(qq/Usage: vcfutils.pl fillac \n\nNote: The GT field MUST BE present and always appear as the first field.\n/) if (@ARGV == 0 && -t STDIN); + while (<>) { + if (/^#/) { + print; + } else { + my @t = split; + my @c = (0, 0); + my $n = 0; + my $s = -1; + @_ = split(":", $t[8]); + for (0 .. $#_) { + if ($_[$_] eq 'GT') { $s = $_; last; } + } + if ($s < 0) { + print join("\t", @t), "\n"; + next; + } + for (9 .. $#t) { + if ($t[$_] =~ /^0,0,0/) { + } elsif ($t[$_] =~ /^([^\s:]+:){$s}(\d+).(\d+)/) { + ++$c[$2]; ++$c[$3]; + $n += 2; + } + } + my $AC = "AC=" . join("\t", @c[1..$#c]) . ";AN=$n"; + my $info = $t[7]; + $info =~ s/(;?)AC=(\d+)//; + $info =~ s/(;?)AN=(\d+)//; + if ($info eq '.') { + $info = $AC; + } else { + $info .= ";$AC"; + } + $t[7] = $info; + print join("\t", @t), "\n"; + } + } +} + +sub ldstats { + my %opts = (t=>0.9); + getopts('t:', \%opts); + die("Usage: vcfutils.pl ldstats [-t $opts{t}] \n") if (@ARGV == 0 && -t STDIN); + my $cutoff = $opts{t}; + my ($last, $lastchr) = (0x7fffffff, ''); + my ($x, $y, $n) = (0, 0, 0); + while (<>) { + if (/^([^#\s]+)\s(\d+)/) { + my ($chr, $pos) = ($1, $2); + if (/NEIR=([\d\.]+)/) { + ++$n; + ++$y, $x += $pos - $last if ($lastchr eq $chr && $pos > $last && $1 > $cutoff); + } + $last = $pos; $lastchr = $chr; + } + } + print "Number of SNP intervals in strong LD (r > $opts{t}): $y\n"; + print "Fraction: ", $y/$n, "\n"; + print "Length: $x\n"; +} + +sub qstats { + my %opts = (r=>'', s=>0.02, v=>undef); + getopts('r:s:v', \%opts); + die("Usage: vcfutils.pl qstats [-r ref.vcf] \n +Note: This command discards indels. Output: QUAL #non-indel #SNPs #transitions #joint ts/tv #joint/#ref #joint/#non-indel \n") if (@ARGV == 0 && -t STDIN); + my %ts = (AG=>1, GA=>1, CT=>1, TC=>1); + my %h = (); + my $is_vcf = defined($opts{v})? 1 : 0; + if ($opts{r}) { # read the reference positions + my $fh; + open($fh, $opts{r}) || die; + while (<$fh>) { + next if (/^#/); + if ($is_vcf) { + my @t = split; + $h{$t[0],$t[1]} = $t[4]; + } else { + $h{$1,$2} = 1 if (/^(\S+)\s+(\d+)/); + } + } + close($fh); + } + my $hsize = scalar(keys %h); + my @a; + while (<>) { + next if (/^#/); + my @t = split; + next if (length($t[3]) != 1 || uc($t[3]) eq 'N'); + $t[3] = uc($t[3]); $t[4] = uc($t[4]); + my @s = split(',', $t[4]); + $t[5] = 3 if ($t[5] eq '.' || $t[5] < 0); + next if (length($s[0]) != 1); + my $hit; + if ($is_vcf) { + $hit = 0; + my $aa = $h{$t[0],$t[1]}; + if (defined($aa)) { + my @aaa = split(",", $aa); + for (@aaa) { + $hit = 1 if ($_ eq $s[0]); + } + } + } else { + $hit = defined($h{$t[0],$t[1]})? 1 : 0; + } + push(@a, [$t[5], ($t[4] eq '.' || $t[4] eq $t[3])? 0 : 1, $ts{$t[3].$s[0]}? 1 : 0, $hit]); + } + push(@a, [-1, 0, 0, 0]); # end marker + die("[qstats] No SNP data!\n") if (@a == 0); + @a = sort {$b->[0]<=>$a->[0]} @a; + my $next = $opts{s}; + my $last = $a[0]; + my @c = (0, 0, 0, 0); + my @lc; + $lc[1] = $lc[2] = 0; + for my $p (@a) { + if ($p->[0] == -1 || ($p->[0] != $last && $c[0]/@a > $next)) { + my @x; + $x[0] = sprintf("%.4f", $c[1]-$c[2]? $c[2] / ($c[1] - $c[2]) : 100); + $x[1] = sprintf("%.4f", $hsize? $c[3] / $hsize : 0); + $x[2] = sprintf("%.4f", $c[3] / $c[1]); + my $a = $c[1] - $lc[1]; + my $b = $c[2] - $lc[2]; + $x[3] = sprintf("%.4f", $a-$b? $b / ($a-$b) : 100); + print join("\t", $last, @c, @x), "\n"; + $next = $c[0]/@a + $opts{s}; + $lc[1] = $c[1]; $lc[2] = $c[2]; + } + ++$c[0]; $c[1] += $p->[1]; $c[2] += $p->[2]; $c[3] += $p->[3]; + $last = $p->[0]; + } +} + +sub varFilter { + my %opts = (d=>2, D=>10000000, a=>2, W=>10, Q=>10, w=>3, p=>undef, 1=>1e-4, 2=>1e-100, 3=>0, 4=>1e-4, G=>0, S=>1000, e=>1e-4); + getopts('pd:D:W:Q:w:a:1:2:3:4:G:S:e:', \%opts); + die(qq/ +Usage: vcfutils.pl varFilter [options] + +Options: -Q INT minimum RMS mapping quality for SNPs [$opts{Q}] + -d INT minimum read depth [$opts{d}] + -D INT maximum read depth [$opts{D}] + -a INT minimum number of alternate bases [$opts{a}] + -w INT SNP within INT bp around a gap to be filtered [$opts{w}] + -W INT window size for filtering adjacent gaps [$opts{W}] + -1 FLOAT min P-value for strand bias (given PV4) [$opts{1}] + -2 FLOAT min P-value for baseQ bias [$opts{2}] + -3 FLOAT min P-value for mapQ bias [$opts{3}] + -4 FLOAT min P-value for end distance bias [$opts{4}] + -e FLOAT min P-value for HWE (plus F<0) [$opts{e}] + -p print filtered variants + +Note: Some of the filters rely on annotations generated by SAMtools\/BCFtools. +\n/) if (@ARGV == 0 && -t STDIN); + + # calculate the window size + my ($ol, $ow) = ($opts{W}, $opts{w}); + my $max_dist = $ol > $ow? $ol : $ow; + # the core loop + my @staging; # (indel_filtering_score, flt_tag, indel_span; chr, pos, ...) + while (<>) { + my @t = split; + if (/^#/) { + print; next; + } + next if ($t[4] eq '.'); # skip non-var sites + next if ($t[3] eq 'N'); # skip sites with unknown ref ('N') + # check if the site is a SNP + my $type = 1; # SNP + if (length($t[3]) > 1) { + $type = 2; # MNP + my @s = split(',', $t[4]); + for (@s) { + $type = 3 if (length != length($t[3])); + } + } else { + my @s = split(',', $t[4]); + for (@s) { + $type = 3 if (length > 1); + } + } + # clear the out-of-range elements + while (@staging) { + # Still on the same chromosome and the first element's window still affects this position? + last if ($staging[0][3] eq $t[0] && $staging[0][4] + $staging[0][2] + $max_dist >= $t[1]); + varFilter_aux(shift(@staging), $opts{p}); # calling a function is a bit slower, not much + } + my $flt = 0; + # parse annotations + my ($dp, $mq, $dp_alt) = (-1, -1, -1); + if ($t[7] =~ /DP4=(\d+),(\d+),(\d+),(\d+)/i) { + $dp = $1 + $2 + $3 + $4; + $dp_alt = $3 + $4; + } + if ($t[7] =~ /DP=(\d+)/i) { + $dp = $1; + } + $mq = $1 if ($t[7] =~ /MQ=(\d+)/i); + # the depth and mapQ filter + if ($dp >= 0) { + if ($dp < $opts{d}) { + $flt = 2; + } elsif ($dp > $opts{D}) { + $flt = 3; + } + } + $flt = 4 if ($dp_alt >= 0 && $dp_alt < $opts{a}); + $flt = 1 if ($flt == 0 && $mq >= 0 && $mq < $opts{Q}); + $flt = 7 if ($flt == 0 && /PV4=([^,]+),([^,]+),([^,]+),([^,;\t]+)/ + && ($1<$opts{1} || $2<$opts{2} || $3<$opts{3} || $4<$opts{4})); + $flt = 8 if ($flt == 0 && ((/MXGQ=(\d+)/ && $1 < $opts{G}) || (/MXSP=(\d+)/ && $1 >= $opts{S}))); + # HWE filter + if ($t[7] =~ /G3=([^;,]+),([^;,]+),([^;,]+).*HWE=([^;,]+)/ && $4 < $opts{e}) { + my $p = 2*$1 + $2; + my $f = ($p > 0 && $p < 1)? 1 - $2 / ($p * (1-$p)) : 0; + $flt = 9 if ($f < 0); + } + + my $score = $t[5] * 100 + $dp_alt; + my $rlen = length($t[3]) - 1; # $indel_score<0 for SNPs + if ($flt == 0) { + if ($type == 3) { # an indel + # filtering SNPs and MNPs + for my $x (@staging) { + next if (($x->[0]&3) == 3 || $x->[1] || $x->[4] + $x->[2] + $ow < $t[1]); + $x->[1] = 5; + } + # check the staging list for indel filtering + for my $x (@staging) { + next if (($x->[0]&3) != 3 || $x->[1] || $x->[4] + $x->[2] + $ol < $t[1]); + if ($x->[0]>>2 < $score) { + $x->[1] = 6; + } else { + $flt = 6; last; + } + } + } else { # SNP or MNP + for my $x (@staging) { + next if (($x->[0]&3) != 3 || $x->[4] + $x->[2] + $ow < $t[1]); + if ($x->[4] + length($x->[7]) - 1 == $t[1] && substr($x->[7], -1, 1) eq substr($t[4], 0, 1) + && length($x->[7]) - length($x->[6]) == 1) { + $x->[1] = 5; + } else { $flt = 5; } + last; + } + # check MNP + for my $x (@staging) { + next if (($x->[0]&3) == 3 || $x->[4] + $x->[2] < $t[1]); + if ($x->[0]>>2 < $score) { + $x->[1] = 8; + } else { + $flt = 8; last; + } + } + } + } + push(@staging, [$score<<2|$type, $flt, $rlen, @t]); + } + # output the last few elements in the staging list + while (@staging) { + varFilter_aux(shift @staging, $opts{p}); + } +} + +sub varFilter_aux { + my ($first, $is_print) = @_; + if ($first->[1] == 0) { + print join("\t", @$first[3 .. @$first-1]), "\n"; + } elsif ($is_print) { + print STDERR join("\t", substr("UQdDaGgPMS", $first->[1], 1), @$first[3 .. @$first-1]), "\n"; + } +} + +sub gapstats { + my (@c0, @c1); + $c0[$_] = $c1[$_] = 0 for (0 .. 10000); + while (<>) { + next if (/^#/); + my @t = split; + next if (length($t[3]) == 1 && $t[4] =~ /^[A-Za-z](,[A-Za-z])*$/); # not an indel + my @s = split(',', $t[4]); + for my $x (@s) { + my $l = length($x) - length($t[3]) + 5000; + if ($x =~ /^-/) { + $l = -(length($x) - 1) + 5000; + } elsif ($x =~ /^\+/) { + $l = length($x) - 1 + 5000; + } + $c0[$l] += 1 / @s; + } + } + for (my $i = 0; $i < 10000; ++$i) { + next if ($c0[$i] == 0); + $c1[0] += $c0[$i]; + $c1[1] += $c0[$i] if (($i-5000)%3 == 0); + printf("C\t%d\t%.2f\n", ($i-5000), $c0[$i]); + } + printf("3\t%d\t%d\t%.3f\n", $c1[0], $c1[1], $c1[1]/$c1[0]); +} + +sub ucscsnp2vcf { + die("Usage: vcfutils.pl \n") if (@ARGV == 0 && -t STDIN); + print "##fileformat=VCFv4.0\n"; + print join("\t", "#CHROM\tPOS\tID\tREF\tALT\tQUAL\tFILTER\tINFO"), "\n"; + while (<>) { + my @t = split("\t"); + my $indel = ($t[9] =~ /^[ACGT](\/[ACGT])+$/)? 0 : 1; + my $pos = $t[2] + 1; + my @alt; + push(@alt, $t[7]); + if ($t[6] eq '-') { + $t[9] = reverse($t[9]); + $t[9] =~ tr/ACGTRYMKWSNacgtrymkwsn/TGCAYRKMWSNtgcayrkmwsn/; + } + my @a = split("/", $t[9]); + for (@a) { + push(@alt, $_) if ($_ ne $alt[0]); + } + if ($indel) { + --$pos; + for (0 .. $#alt) { + $alt[$_] =~ tr/-//d; + $alt[$_] = "N$alt[$_]"; + } + } + my $ref = shift(@alt); + my $af = $t[13] > 0? ";AF=$t[13]" : ''; + my $valid = ($t[12] eq 'unknown')? '' : ";valid=$t[12]"; + my $info = "molType=$t[10];class=$t[11]$valid$af"; + print join("\t", $t[1], $pos, $t[4], $ref, join(",", @alt), 0, '.', $info), "\n"; + } +} + +sub hapmap2vcf { + die("Usage: vcfutils.pl \n") if (@ARGV == 0); + my $fn = shift(@ARGV); + # parse UCSC SNP + warn("Parsing UCSC SNPs...\n"); + my ($fh, %map); + open($fh, ($fn =~ /\.gz$/)? "gzip -dc $fn |" : $fn) || die; + while (<$fh>) { + my @t = split; + next if ($t[3] - $t[2] != 1); # not SNP + @{$map{$t[4]}} = @t[1,3,7]; + } + close($fh); + # write VCF + warn("Writing VCF...\n"); + print "##fileformat=VCFv4.0\n"; + while (<>) { + my @t = split; + if ($t[0] eq 'rs#') { # the first line + print join("\t", "#CHROM\tPOS\tID\tREF\tALT\tQUAL\tFILTER\tINFO\tFORMAT", @t[11..$#t]), "\n"; + } else { + next unless ($map{$t[0]}); + next if (length($t[1]) != 3); # skip non-SNPs + my $a = \@{$map{$t[0]}}; + my $ref = $a->[2]; + my @u = split('/', $t[1]); + if ($u[1] eq $ref) { + $u[1] = $u[0]; $u[0] = $ref; + } elsif ($u[0] ne $ref) { next; } + my $alt = $u[1]; + my %w; + $w{$u[0]} = 0; $w{$u[1]} = 1; + my @s = (@$a[0,1], $t[0], $ref, $alt, 0, '.', '.', 'GT'); + my $is_tri = 0; + for (@t[11..$#t]) { + if ($_ eq 'NN') { + push(@s, './.'); + } else { + my @a = ($w{substr($_,0,1)}, $w{substr($_,1,1)}); + if (!defined($a[0]) || !defined($a[1])) { + $is_tri = 1; + last; + } + push(@s, "$a[0]/$a[1]"); + } + } + next if ($is_tri); + print join("\t", @s), "\n"; + } + } +} + +sub vcf2fq { + my %opts = (d=>3, D=>100000, Q=>10, l=>5); + getopts('d:D:Q:l:', \%opts); + die(qq/ +Usage: vcfutils.pl vcf2fq [options] + +Options: -d INT minimum depth [$opts{d}] + -D INT maximum depth [$opts{D}] + -Q INT min RMS mapQ [$opts{Q}] + -l INT INDEL filtering window [$opts{l}] +\n/) if (@ARGV == 0 && -t STDIN); + + my ($last_chr, $seq, $qual, $last_pos, @gaps); + my $_Q = $opts{Q}; + my $_d = $opts{d}; + my $_D = $opts{D}; + + my %het = (AC=>'M', AG=>'R', AT=>'W', CA=>'M', CG=>'S', CT=>'Y', + GA=>'R', GC=>'S', GT=>'K', TA=>'W', TC=>'Y', TG=>'K'); + + $last_chr = ''; + while (<>) { + next if (/^#/); + my @t = split; + if ($last_chr ne $t[0]) { + &v2q_post_process($last_chr, \$seq, \$qual, \@gaps, $opts{l}) if ($last_chr); + ($last_chr, $last_pos) = ($t[0], 0); + $seq = $qual = ''; + @gaps = (); + } + die("[vcf2fq] unsorted input\n") if ($t[1] - $last_pos < 0); + if ($t[1] - $last_pos > 1) { + $seq .= 'n' x ($t[1] - $last_pos - 1); + $qual .= '!' x ($t[1] - $last_pos - 1); + } + if (length($t[3]) == 1 && $t[7] !~ /INDEL/ && $t[4] =~ /^([A-Za-z.])(,[A-Za-z])*$/) { # a SNP or reference + my ($ref, $alt) = ($t[3], $1); + my ($b, $q); + $q = $1 if ($t[7] =~ /FQ=(-?[\d\.]+)/); + if ($q < 0) { + $_ = ($t[7] =~ /AF1=([\d\.]+)/)? $1 : 0; + $b = ($_ < .5 || $alt eq '.')? $ref : $alt; + $q = -$q; + } else { + $b = $het{"$ref$alt"}; + $b ||= 'N'; + } + $b = lc($b); + $b = uc($b) if (($t[7] =~ /MQ=(\d+)/ && $1 >= $_Q) && ($t[7] =~ /DP=(\d+)/ && $1 >= $_d && $1 <= $_D)); + $q = int($q + 33 + .499); + $q = chr($q <= 126? $q : 126); + $seq .= $b; + $qual .= $q; + } elsif ($t[4] ne '.') { # an INDEL + push(@gaps, [$t[1], length($t[3])]); + } + $last_pos = $t[1]; + } + &v2q_post_process($last_chr, \$seq, \$qual, \@gaps, $opts{l}); +} + +sub v2q_post_process { + my ($chr, $seq, $qual, $gaps, $l) = @_; + for my $g (@$gaps) { + my $beg = $g->[0] > $l? $g->[0] - $l : 0; + my $end = $g->[0] + $g->[1] + $l; + $end = length($$seq) if ($end > length($$seq)); + substr($$seq, $beg, $end - $beg) = lc(substr($$seq, $beg, $end - $beg)); + } + print "\@$chr\n"; &v2q_print_str($seq); + print "+\n"; &v2q_print_str($qual); +} + +sub v2q_print_str { + my ($s) = @_; + my $l = length($$s); + for (my $i = 0; $i < $l; $i += 60) { + print substr($$s, $i, 60), "\n"; + } +} + +sub usage { + die(qq/ +Usage: vcfutils.pl []\n +Command: subsam get a subset of samples + listsam list the samples + fillac fill the allele count field + qstats SNP stats stratified by QUAL + + hapmap2vcf convert the hapmap format to VCF + ucscsnp2vcf convert UCSC SNP SQL dump to VCF + + varFilter filtering short variants (*) + vcf2fq VCF->fastq (**) + +Notes: Commands with description endting with (*) may need bcftools + specific annotations. +\n/); +} diff --git a/mpileup.c b/mpileup.c new file mode 100644 index 0000000..ac37dd4 --- /dev/null +++ b/mpileup.c @@ -0,0 +1,1110 @@ +/* mpileup.c -- mpileup subcommand. Previously bam_plcmd.c from samtools + + Copyright (C) 2008-2017 Genome Research Ltd. + Portions copyright (C) 2009-2012 Broad Institute. + + Author: Heng Li + +Permission is hereby granted, free of charge, to any person obtaining a copy +of this software and associated documentation files (the "Software"), to deal +in the Software without restriction, including without limitation the rights +to use, copy, modify, merge, publish, distribute, sublicense, and/or sell +copies of the Software, and to permit persons to whom the Software is +furnished to do so, subject to the following conditions: + +The above copyright notice and this permission notice shall be included in +all copies or substantial portions of the Software. + +THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL +THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER +LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING +FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER +DEALINGS IN THE SOFTWARE. */ + +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include "regidx.h" +#include "bcftools.h" +#include "bam2bcf.h" +#include "bam_sample.h" +#include "gvcf.h" + +#define MPLP_BCF 1 +#define MPLP_VCF (1<<1) +#define MPLP_NO_COMP (1<<2) +#define MPLP_NO_ORPHAN (1<<3) +#define MPLP_REALN (1<<4) +#define MPLP_NO_INDEL (1<<5) +#define MPLP_REDO_BAQ (1<<6) +#define MPLP_ILLUMINA13 (1<<7) +#define MPLP_IGNORE_RG (1<<8) +#define MPLP_PRINT_POS (1<<9) +#define MPLP_PRINT_MAPQ (1<<10) +#define MPLP_PER_SAMPLE (1<<11) +#define MPLP_SMART_OVERLAPS (1<<12) + +typedef struct _mplp_aux_t mplp_aux_t; +typedef struct _mplp_pileup_t mplp_pileup_t; + +// Data shared by all bam files +typedef struct { + int min_mq, flag, min_baseQ, capQ_thres, max_depth, max_indel_depth, fmt_flag; + int rflag_require, rflag_filter, output_type; + int openQ, extQ, tandemQ, min_support; // for indels + double min_frac; // for indels + char *reg_fname, *pl_list, *fai_fname, *output_fname; + int reg_is_file, record_cmd_line, n_threads; + faidx_t *fai; + regidx_t *bed, *reg; // bed: skipping regions, reg: index-jump to regions + regitr_t *bed_itr, *reg_itr; + int bed_logic; // 1: include region, 0: exclude region + gvcf_t *gvcf; + + // auxiliary structures for calling + bcf_callaux_t *bca; + bcf_callret1_t *bcr; + bcf_call_t bc; + bam_mplp_t iter; + mplp_aux_t **mplp_data; + int nfiles; + char **files; + mplp_pileup_t *gplp; + int *n_plp; + const bam_pileup1_t **plp; + bam_smpl_t *bsmpl; + kstring_t buf; + bcf1_t *bcf_rec; + htsFile *bcf_fp; + bcf_hdr_t *bcf_hdr; + int argc; + char **argv; +} mplp_conf_t; + +typedef struct { + char *ref[2]; + int ref_id[2]; + int ref_len[2]; +} mplp_ref_t; + +#define MPLP_REF_INIT {{NULL,NULL},{-1,-1},{0,0}} + +// Data specific to each bam file +struct _mplp_aux_t { + samFile *fp; + hts_itr_t *iter; + bam_hdr_t *h; + mplp_ref_t *ref; + const mplp_conf_t *conf; + int bam_id; + hts_idx_t *idx; // maintained only with more than one -r regions +}; + +// Data passed to htslib/mpileup +struct _mplp_pileup_t { + int n; + int *n_plp, *m_plp; + bam_pileup1_t **plp; +}; + +static int mplp_get_ref(mplp_aux_t *ma, int tid, char **ref, int *ref_len) { + mplp_ref_t *r = ma->ref; + + //printf("get ref %d {%d/%p, %d/%p}\n", tid, r->ref_id[0], r->ref[0], r->ref_id[1], r->ref[1]); + + if (!r || !ma->conf->fai) { + *ref = NULL; + return 0; + } + + // Do we need to reference count this so multiple mplp_aux_t can + // track which references are in use? + // For now we just cache the last two. Sufficient? + if (tid == r->ref_id[0]) { + *ref = r->ref[0]; + *ref_len = r->ref_len[0]; + return 1; + } + if (tid == r->ref_id[1]) { + // Last, swap over + int tmp; + tmp = r->ref_id[0]; r->ref_id[0] = r->ref_id[1]; r->ref_id[1] = tmp; + tmp = r->ref_len[0]; r->ref_len[0] = r->ref_len[1]; r->ref_len[1] = tmp; + + char *tc; + tc = r->ref[0]; r->ref[0] = r->ref[1]; r->ref[1] = tc; + *ref = r->ref[0]; + *ref_len = r->ref_len[0]; + return 1; + } + + // New, so migrate to old and load new + free(r->ref[1]); + r->ref[1] = r->ref[0]; + r->ref_id[1] = r->ref_id[0]; + r->ref_len[1] = r->ref_len[0]; + + r->ref_id[0] = tid; + r->ref[0] = faidx_fetch_seq(ma->conf->fai, + ma->h->target_name[r->ref_id[0]], + 0, + INT_MAX, + &r->ref_len[0]); + + if (!r->ref[0]) { + r->ref[0] = NULL; + r->ref_id[0] = -1; + r->ref_len[0] = 0; + *ref = NULL; + return 0; + } + + *ref = r->ref[0]; + *ref_len = r->ref_len[0]; + return 1; +} + +static int mplp_func(void *data, bam1_t *b) +{ + char *ref; + mplp_aux_t *ma = (mplp_aux_t*)data; + int ret, ref_len; + while (1) + { + int has_ref; + ret = ma->iter? sam_itr_next(ma->fp, ma->iter, b) : sam_read1(ma->fp, ma->h, b); + if (ret < 0) break; + // The 'B' cigar operation is not part of the specification, considering as obsolete. + // bam_remove_B(b); + if (b->core.tid < 0 || (b->core.flag&BAM_FUNMAP)) continue; // exclude unmapped reads + if (ma->conf->rflag_require && !(ma->conf->rflag_require&b->core.flag)) continue; + if (ma->conf->rflag_filter && ma->conf->rflag_filter&b->core.flag) continue; + if (ma->conf->bed) + { + // test overlap + regitr_t *itr = ma->conf->bed_itr; + int beg = b->core.pos, end = bam_endpos(b)-1; + int overlap = regidx_overlap(ma->conf->bed, ma->h->target_name[b->core.tid],beg,end, itr); + if ( !ma->conf->bed_logic && !overlap ) + { + // exclude only reads which are fully contained in the region + while ( regitr_overlap(itr) ) + { + if ( beg < itr->beg ) { overlap = 1; break; } + if ( end > itr->end ) { overlap = 1; break; } + } + } + if ( !overlap ) continue; + } + if ( bam_smpl_get_sample_id(ma->conf->bsmpl,ma->bam_id,b)<0 ) continue; + if (ma->conf->flag & MPLP_ILLUMINA13) { + int i; + uint8_t *qual = bam_get_qual(b); + for (i = 0; i < b->core.l_qseq; ++i) + qual[i] = qual[i] > 31? qual[i] - 31 : 0; + } + + if (ma->conf->fai && b->core.tid >= 0) { + has_ref = mplp_get_ref(ma, b->core.tid, &ref, &ref_len); + if (has_ref && ref_len <= b->core.pos) { // exclude reads outside of the reference sequence + fprintf(stderr,"[%s] Skipping because %d is outside of %d [ref:%d]\n", + __func__, b->core.pos, ref_len, b->core.tid); + continue; + } + } else { + has_ref = 0; + } + + if (has_ref && (ma->conf->flag&MPLP_REALN)) sam_prob_realn(b, ref, ref_len, (ma->conf->flag & MPLP_REDO_BAQ)? 7 : 3); + if (has_ref && ma->conf->capQ_thres > 10) { + int q = sam_cap_mapq(b, ref, ref_len, ma->conf->capQ_thres); + if (q < 0) continue; // skip + else if (b->core.qual > q) b->core.qual = q; + } + if (b->core.qual < ma->conf->min_mq) continue; + else if ((ma->conf->flag&MPLP_NO_ORPHAN) && (b->core.flag&BAM_FPAIRED) && !(b->core.flag&BAM_FPROPER_PAIR)) continue; + + return ret; + }; + return ret; +} + +// Called once per new bam added to the pileup. +// We cache sample information here so we don't have to keep recomputing this +// on each and every pileup column. +// +// Cd is an arbitrary block of data we can write into, which ends up in +// the pileup structures. We stash the sample ID there. +static int pileup_constructor(void *data, const bam1_t *b, bam_pileup_cd *cd) { + mplp_aux_t *ma = (mplp_aux_t *)data; + cd->i = bam_smpl_get_sample_id(ma->conf->bsmpl, ma->bam_id, (bam1_t *)b); + return 0; +} + +static void group_smpl(mplp_pileup_t *m, bam_smpl_t *bsmpl, int n, int *n_plp, const bam_pileup1_t **plp) +{ + int i, j; + memset(m->n_plp, 0, m->n * sizeof(int)); + for (i = 0; i < n; ++i) // iterate over all bams + { + for (j = 0; j < n_plp[i]; ++j) // iterate over all reads available at this position + { + const bam_pileup1_t *p = plp[i] + j; + int id = p->cd.i; + if (m->n_plp[id] == m->m_plp[id]) + { + m->m_plp[id] = m->m_plp[id]? m->m_plp[id]<<1 : 8; + m->plp[id] = (bam_pileup1_t*) realloc(m->plp[id], sizeof(bam_pileup1_t) * m->m_plp[id]); + } + m->plp[id][m->n_plp[id]++] = *p; + } + } +} + +static void flush_bcf_records(mplp_conf_t *conf, htsFile *fp, bcf_hdr_t *hdr, bcf1_t *rec) +{ + if ( !conf->gvcf ) + { + if ( rec ) bcf_write1(fp, hdr, rec); + return; + } + + if ( !rec ) + { + gvcf_write(conf->gvcf, fp, hdr, NULL, 0); + return; + } + + int is_ref = 0; + if ( rec->n_allele==1 ) is_ref = 1; + else if ( rec->n_allele==2 ) + { + // second allele is mpileup's X, not a variant + if ( rec->d.allele[1][0]=='<' && rec->d.allele[1][1]=='*' && rec->d.allele[1][2]=='>' ) is_ref = 1; + } + rec = gvcf_write(conf->gvcf, fp, hdr, rec, is_ref); + if ( rec ) bcf_write1(fp,hdr,rec); +} + +static int mpileup_reg(mplp_conf_t *conf, uint32_t beg, uint32_t end) +{ + bam_hdr_t *hdr = conf->mplp_data[0]->h; // header of first file in input list + + int ret, i, tid, pos, ref_len; + char *ref; + + while ( (ret=bam_mplp_auto(conf->iter, &tid, &pos, conf->n_plp, conf->plp)) > 0) + { + if ( end && (posend) ) continue; + if ( conf->bed && tid >= 0 ) + { + int overlap = regidx_overlap(conf->bed, hdr->target_name[tid], pos, pos, NULL); + if ( !conf->bed_logic ) overlap = overlap ? 0 : 1; + if ( !overlap ) continue; + } + mplp_get_ref(conf->mplp_data[0], tid, &ref, &ref_len); + + int total_depth, _ref0, ref16; + for (i = total_depth = 0; i < conf->nfiles; ++i) total_depth += conf->n_plp[i]; + group_smpl(conf->gplp, conf->bsmpl, conf->nfiles, conf->n_plp, conf->plp); + _ref0 = (ref && pos < ref_len)? ref[pos] : 'N'; + ref16 = seq_nt16_table[_ref0]; + bcf_callaux_clean(conf->bca, &conf->bc); + for (i = 0; i < conf->gplp->n; ++i) + bcf_call_glfgen(conf->gplp->n_plp[i], conf->gplp->plp[i], ref16, conf->bca, conf->bcr + i); + conf->bc.tid = tid; conf->bc.pos = pos; + bcf_call_combine(conf->gplp->n, conf->bcr, conf->bca, ref16, &conf->bc); + bcf_clear1(conf->bcf_rec); + bcf_call2bcf(&conf->bc, conf->bcf_rec, conf->bcr, conf->fmt_flag, 0, 0); + flush_bcf_records(conf, conf->bcf_fp, conf->bcf_hdr, conf->bcf_rec); + + // call indels; todo: subsampling with total_depth>max_indel_depth instead of ignoring? + // check me: rghash in bcf_call_gap_prep() should have no effect, reads mplp_func already excludes them + if (!(conf->flag&MPLP_NO_INDEL) && total_depth < conf->max_indel_depth + && bcf_call_gap_prep(conf->gplp->n, conf->gplp->n_plp, conf->gplp->plp, pos, conf->bca, ref) >= 0) + { + bcf_callaux_clean(conf->bca, &conf->bc); + for (i = 0; i < conf->gplp->n; ++i) + bcf_call_glfgen(conf->gplp->n_plp[i], conf->gplp->plp[i], -1, conf->bca, conf->bcr + i); + if (bcf_call_combine(conf->gplp->n, conf->bcr, conf->bca, -1, &conf->bc) >= 0) + { + bcf_clear1(conf->bcf_rec); + bcf_call2bcf(&conf->bc, conf->bcf_rec, conf->bcr, conf->fmt_flag, conf->bca, ref); + flush_bcf_records(conf, conf->bcf_fp, conf->bcf_hdr, conf->bcf_rec); + } + } + } + return 0; +} + +static int mpileup(mplp_conf_t *conf) +{ + if (conf->nfiles == 0) { + fprintf(stderr,"[%s] no input file/data given\n", __func__); + exit(EXIT_FAILURE); + } + + mplp_ref_t mp_ref = MPLP_REF_INIT; + conf->gplp = (mplp_pileup_t *) calloc(1,sizeof(mplp_pileup_t)); + conf->mplp_data = (mplp_aux_t**) calloc(conf->nfiles, sizeof(mplp_aux_t*)); + conf->plp = (const bam_pileup1_t**) calloc(conf->nfiles, sizeof(bam_pileup1_t*)); + conf->n_plp = (int*) calloc(conf->nfiles, sizeof(int)); + + // Allow to run mpileup on multiple regions in one go. This comes at cost: the bai index + // must be kept in the memory for the whole time which can be a problem with many bams. + // Therefore if none or only one region is requested, we initialize the bam iterator as + // before and free the index. Only when multiple regions are queried, we keep the index. + int nregs = 0; + if ( conf->reg_fname ) + { + if ( conf->reg_is_file ) + { + conf->reg = regidx_init(conf->reg_fname,NULL,NULL,0,NULL); + if ( !conf->reg ) { + fprintf(stderr,"Could not parse the regions: %s\n", conf->reg_fname); + exit(EXIT_FAILURE); + } + } + else + { + conf->reg = regidx_init(NULL,regidx_parse_reg,NULL,sizeof(char*),NULL); + if ( regidx_insert_list(conf->reg,conf->reg_fname,',') !=0 ) { + fprintf(stderr,"Could not parse the regions: %s\n", conf->reg_fname); + exit(EXIT_FAILURE); + } + } + nregs = regidx_nregs(conf->reg); + conf->reg_itr = regitr_init(conf->reg); + regitr_loop(conf->reg_itr); // region iterator now positioned at the first region + } + + // read the header of each file in the list and initialize data + // beware: mpileup has always assumed that tid's are consistent in the headers, add sanity check at least! + bam_hdr_t *hdr = NULL; // header of first file in input list + int i; + for (i = 0; i < conf->nfiles; ++i) { + bam_hdr_t *h_tmp; + conf->mplp_data[i] = (mplp_aux_t*) calloc(1, sizeof(mplp_aux_t)); + conf->mplp_data[i]->fp = sam_open(conf->files[i], "rb"); + if ( !conf->mplp_data[i]->fp ) + { + fprintf(stderr, "[%s] failed to open %s: %s\n", __func__, conf->files[i], strerror(errno)); + exit(EXIT_FAILURE); + } + if (hts_set_opt(conf->mplp_data[i]->fp, CRAM_OPT_DECODE_MD, 0)) { + fprintf(stderr, "Failed to set CRAM_OPT_DECODE_MD value\n"); + exit(EXIT_FAILURE); + } + if (conf->fai_fname && hts_set_fai_filename(conf->mplp_data[i]->fp, conf->fai_fname) != 0) { + fprintf(stderr, "[%s] failed to process %s: %s\n", + __func__, conf->fai_fname, strerror(errno)); + exit(EXIT_FAILURE); + } + conf->mplp_data[i]->conf = conf; + conf->mplp_data[i]->ref = &mp_ref; + h_tmp = sam_hdr_read(conf->mplp_data[i]->fp); + if ( !h_tmp ) { + fprintf(stderr,"[%s] fail to read the header of %s\n", __func__, conf->files[i]); + exit(EXIT_FAILURE); + } + conf->mplp_data[i]->h = i ? hdr : h_tmp; // for j==0, "h" has not been set yet + conf->mplp_data[i]->bam_id = bam_smpl_add_bam(conf->bsmpl,h_tmp->text,conf->files[i]); + if ( conf->mplp_data[i]->bam_id<0 ) + { + // no usable readgroups in this bam, it can be skipped + sam_close(conf->mplp_data[i]->fp); + free(conf->mplp_data[i]); + bam_hdr_destroy(h_tmp); + free(conf->files[i]); + if ( i+1nfiles ) memmove(&conf->files[i],&conf->files[i+1],sizeof(*conf->files)*(conf->nfiles-i-1)); + conf->nfiles--; + i--; + continue; + } + if (conf->reg) { + hts_idx_t *idx = sam_index_load(conf->mplp_data[i]->fp, conf->files[i]); + if (idx == NULL) { + fprintf(stderr, "[%s] fail to load index for %s\n", __func__, conf->files[i]); + exit(EXIT_FAILURE); + } + conf->buf.l = 0; + ksprintf(&conf->buf,"%s:%u-%u",conf->reg_itr->seq,conf->reg_itr->beg+1,conf->reg_itr->end+1); + conf->mplp_data[i]->iter = sam_itr_querys(idx, conf->mplp_data[i]->h, conf->buf.s); + if ( !conf->mplp_data[i]->iter ) + { + conf->mplp_data[i]->iter = sam_itr_querys(idx, conf->mplp_data[i]->h, conf->reg_itr->seq); + if ( conf->mplp_data[i]->iter ) { + fprintf(stderr,"[E::%s] fail to parse region '%s'\n", __func__, conf->buf.s); + exit(EXIT_FAILURE); + } + fprintf(stderr,"[E::%s] the sequence \"%s\" not found: %s\n",__func__,conf->reg_itr->seq,conf->files[i]); + exit(EXIT_FAILURE); + } + if ( nregs==1 ) // no need to keep the index in memory + hts_idx_destroy(idx); + else + conf->mplp_data[i]->idx = idx; + } + + if ( !hdr ) hdr = h_tmp; /* save the header of first file in list */ + else { + // FIXME: check consistency between h and h_tmp + bam_hdr_destroy(h_tmp); + + // we store only the first file's header; it's (alleged to be) + // compatible with the i-th file's target_name lookup needs + conf->mplp_data[i]->h = hdr; + } + } + // allocate data storage proportionate to number of samples being studied sm->n + bam_smpl_get_samples(conf->bsmpl, &conf->gplp->n); + conf->gplp->n_plp = (int*) calloc(conf->gplp->n, sizeof(int)); + conf->gplp->m_plp = (int*) calloc(conf->gplp->n, sizeof(int)); + conf->gplp->plp = (bam_pileup1_t**) calloc(conf->gplp->n, sizeof(bam_pileup1_t*)); + + fprintf(stderr, "[%s] %d samples in %d input files\n", __func__, conf->gplp->n, conf->nfiles); + // write the VCF header + conf->bcf_fp = hts_open(conf->output_fname?conf->output_fname:"-", hts_bcf_wmode(conf->output_type)); + if (conf->bcf_fp == NULL) { + fprintf(stderr, "[%s] failed to write to %s: %s\n", __func__, conf->output_fname? conf->output_fname : "standard output", strerror(errno)); + exit(EXIT_FAILURE); + } + if ( conf->n_threads ) hts_set_threads(conf->bcf_fp, conf->n_threads); + + // BCF header creation + conf->bcf_hdr = bcf_hdr_init("w"); + conf->buf.l = 0; + + if (conf->record_cmd_line) + { + ksprintf(&conf->buf, "##bcftoolsVersion=%s+htslib-%s\n",bcftools_version(),hts_version()); + bcf_hdr_append(conf->bcf_hdr, conf->buf.s); + + conf->buf.l = 0; + ksprintf(&conf->buf, "##bcftoolsCommand=mpileup"); + for (i=1; iargc; i++) ksprintf(&conf->buf, " %s", conf->argv[i]); + kputc('\n', &conf->buf); + bcf_hdr_append(conf->bcf_hdr, conf->buf.s); + } + + if (conf->fai_fname) + { + conf->buf.l = 0; + ksprintf(&conf->buf, "##reference=file://%s\n", conf->fai_fname); + bcf_hdr_append(conf->bcf_hdr, conf->buf.s); + } + + // Translate BAM @SQ tags to BCF ##contig tags + // todo: use/write new BAM header manipulation routines, fill also UR, M5 + for (i=0; in_targets; i++) + { + conf->buf.l = 0; + ksprintf(&conf->buf, "##contig=", hdr->target_name[i], hdr->target_len[i]); + bcf_hdr_append(conf->bcf_hdr, conf->buf.s); + } + conf->buf.l = 0; + + bcf_hdr_append(conf->bcf_hdr,"##ALT="); + bcf_hdr_append(conf->bcf_hdr,"##INFO="); + bcf_hdr_append(conf->bcf_hdr,"##INFO="); + bcf_hdr_append(conf->bcf_hdr,"##INFO="); + bcf_hdr_append(conf->bcf_hdr,"##INFO="); + bcf_hdr_append(conf->bcf_hdr,"##INFO="); + bcf_hdr_append(conf->bcf_hdr,"##INFO="); + bcf_hdr_append(conf->bcf_hdr,"##INFO="); + bcf_hdr_append(conf->bcf_hdr,"##INFO="); + bcf_hdr_append(conf->bcf_hdr,"##INFO="); +#if CDF_MWU_TESTS + bcf_hdr_append(conf->bcf_hdr,"##INFO="); + bcf_hdr_append(conf->bcf_hdr,"##INFO="); + bcf_hdr_append(conf->bcf_hdr,"##INFO="); + bcf_hdr_append(conf->bcf_hdr,"##INFO="); +#endif + bcf_hdr_append(conf->bcf_hdr,"##INFO="); + bcf_hdr_append(conf->bcf_hdr,"##INFO="); + bcf_hdr_append(conf->bcf_hdr,"##INFO="); + bcf_hdr_append(conf->bcf_hdr,"##INFO="); + bcf_hdr_append(conf->bcf_hdr,"##FORMAT="); + if ( conf->fmt_flag&B2B_FMT_DP ) + bcf_hdr_append(conf->bcf_hdr,"##FORMAT="); + if ( conf->fmt_flag&B2B_FMT_DV ) + bcf_hdr_append(conf->bcf_hdr,"##FORMAT="); + if ( conf->fmt_flag&B2B_FMT_DPR ) + bcf_hdr_append(conf->bcf_hdr,"##FORMAT="); + if ( conf->fmt_flag&B2B_INFO_DPR ) + bcf_hdr_append(conf->bcf_hdr,"##INFO="); + if ( conf->fmt_flag&B2B_FMT_DP4 ) + bcf_hdr_append(conf->bcf_hdr,"##FORMAT="); + if ( conf->fmt_flag&B2B_FMT_SP ) + bcf_hdr_append(conf->bcf_hdr,"##FORMAT="); + if ( conf->fmt_flag&B2B_FMT_AD ) + bcf_hdr_append(conf->bcf_hdr,"##FORMAT="); + if ( conf->fmt_flag&B2B_FMT_ADF ) + bcf_hdr_append(conf->bcf_hdr,"##FORMAT="); + if ( conf->fmt_flag&B2B_FMT_ADR ) + bcf_hdr_append(conf->bcf_hdr,"##FORMAT="); + if ( conf->fmt_flag&B2B_INFO_AD ) + bcf_hdr_append(conf->bcf_hdr,"##INFO="); + if ( conf->fmt_flag&B2B_INFO_ADF ) + bcf_hdr_append(conf->bcf_hdr,"##INFO="); + if ( conf->fmt_flag&B2B_INFO_ADR ) + bcf_hdr_append(conf->bcf_hdr,"##INFO="); + if ( conf->gvcf ) + gvcf_update_header(conf->gvcf, conf->bcf_hdr); + + int nsmpl; + const char **smpl = bam_smpl_get_samples(conf->bsmpl, &nsmpl); + for (i=0; ibcf_hdr, smpl[i]); + bcf_hdr_write(conf->bcf_fp, conf->bcf_hdr); + + conf->bca = bcf_call_init(-1., conf->min_baseQ); + conf->bcr = (bcf_callret1_t*) calloc(nsmpl, sizeof(bcf_callret1_t)); + conf->bca->openQ = conf->openQ, conf->bca->extQ = conf->extQ, conf->bca->tandemQ = conf->tandemQ; + conf->bca->min_frac = conf->min_frac; + conf->bca->min_support = conf->min_support; + conf->bca->per_sample_flt = conf->flag & MPLP_PER_SAMPLE; + + conf->bc.bcf_hdr = conf->bcf_hdr; + conf->bc.n = nsmpl; + conf->bc.PL = (int32_t*) malloc(15 * nsmpl * sizeof(*conf->bc.PL)); + if (conf->fmt_flag) + { + assert( sizeof(float)==sizeof(int32_t) ); + conf->bc.DP4 = (int32_t*) malloc(nsmpl * sizeof(int32_t) * 4); + conf->bc.fmt_arr = (uint8_t*) malloc(nsmpl * sizeof(float)); // all fmt_flag fields, float and int32 + if ( conf->fmt_flag&(B2B_INFO_DPR|B2B_FMT_DPR|B2B_INFO_AD|B2B_INFO_ADF|B2B_INFO_ADR|B2B_FMT_AD|B2B_FMT_ADF|B2B_FMT_ADR) ) + { + // first B2B_MAX_ALLELES fields for total numbers, the rest per-sample + conf->bc.ADR = (int32_t*) malloc((nsmpl+1)*B2B_MAX_ALLELES*sizeof(int32_t)); + conf->bc.ADF = (int32_t*) malloc((nsmpl+1)*B2B_MAX_ALLELES*sizeof(int32_t)); + for (i=0; ibcr[i].ADR = conf->bc.ADR + (i+1)*B2B_MAX_ALLELES; + conf->bcr[i].ADF = conf->bc.ADF + (i+1)*B2B_MAX_ALLELES; + } + } + } + + // init mpileup + conf->iter = bam_mplp_init(conf->nfiles, mplp_func, (void**)conf->mplp_data); + if ( conf->flag & MPLP_SMART_OVERLAPS ) bam_mplp_init_overlaps(conf->iter); + if ( (double)conf->max_depth * conf->nfiles > 1<<20) + fprintf(stderr, "Warning: Potential memory hog, up to %.0fM reads in the pileup!\n", (double)conf->max_depth*conf->nfiles); + if ( (double)conf->max_depth * conf->nfiles / nsmpl < 250 ) + fprintf(stderr, "Note: The maximum per-sample depth with -d %d is %.1fx\n", conf->max_depth,(double)conf->max_depth * conf->nfiles / nsmpl); + bam_mplp_set_maxcnt(conf->iter, conf->max_depth); + conf->max_indel_depth = conf->max_indel_depth * nsmpl; + conf->bcf_rec = bcf_init1(); + bam_mplp_constructor(conf->iter, pileup_constructor); + + // Run mpileup for multiple regions + if ( nregs ) + { + int ireg = 0; + do + { + // first region is already positioned + if ( ireg++ > 0 ) + { + conf->buf.l = 0; + ksprintf(&conf->buf,"%s:%u-%u",conf->reg_itr->seq,conf->reg_itr->beg,conf->reg_itr->end); + + for (i=0; infiles; i++) + { + hts_itr_destroy(conf->mplp_data[i]->iter); + conf->mplp_data[i]->iter = sam_itr_querys(conf->mplp_data[i]->idx, conf->mplp_data[i]->h, conf->buf.s); + if ( !conf->mplp_data[i]->iter ) + { + conf->mplp_data[i]->iter = sam_itr_querys(conf->mplp_data[i]->idx, conf->mplp_data[i]->h, conf->reg_itr->seq); + if ( conf->mplp_data[i]->iter ) { + fprintf(stderr,"[E::%s] fail to parse region '%s'\n", __func__, conf->buf.s); + exit(EXIT_FAILURE); + } + fprintf(stderr,"[E::%s] the sequence \"%s\" not found: %s\n",__func__,conf->reg_itr->seq,conf->files[i]); + exit(EXIT_FAILURE); + } + bam_mplp_reset(conf->iter); + } + } + mpileup_reg(conf,conf->reg_itr->beg,conf->reg_itr->end); + } + while ( regitr_loop(conf->reg_itr) ); + } + else + mpileup_reg(conf,0,0); + + flush_bcf_records(conf, conf->bcf_fp, conf->bcf_hdr, NULL); + + // clean up + free(conf->bc.tmp.s); + bcf_destroy1(conf->bcf_rec); + if (conf->bcf_fp) + { + hts_close(conf->bcf_fp); + bcf_hdr_destroy(conf->bcf_hdr); + bcf_call_destroy(conf->bca); + free(conf->bc.PL); + free(conf->bc.DP4); + free(conf->bc.ADR); + free(conf->bc.ADF); + free(conf->bc.fmt_arr); + free(conf->bcr); + } + if ( conf->gvcf ) gvcf_destroy(conf->gvcf); + free(conf->buf.s); + for (i = 0; i < conf->gplp->n; ++i) free(conf->gplp->plp[i]); + free(conf->gplp->plp); free(conf->gplp->n_plp); free(conf->gplp->m_plp); free(conf->gplp); + bam_mplp_destroy(conf->iter); + bam_hdr_destroy(hdr); + for (i = 0; i < conf->nfiles; ++i) { + if ( nregs>1 ) hts_idx_destroy(conf->mplp_data[i]->idx); + sam_close(conf->mplp_data[i]->fp); + if ( conf->mplp_data[i]->iter) hts_itr_destroy(conf->mplp_data[i]->iter); + free(conf->mplp_data[i]); + } + if ( conf->reg_itr ) regitr_destroy(conf->reg_itr); + free(conf->mplp_data); free(conf->plp); free(conf->n_plp); + free(mp_ref.ref[0]); + free(mp_ref.ref[1]); + return 0; +} + +static int is_url(const char *s) +{ + static const char uri_scheme_chars[] = + "ABCDEFGHIJKLMNOPQRSTUVWXYZabcdefghijklmnopqrstuvwxyz0123456789+.-"; + return s[strspn(s, uri_scheme_chars)] == ':'; +} + +#define MAX_PATH_LEN 1024 +int read_file_list(const char *file_list,int *n,char **argv[]) +{ + char buf[MAX_PATH_LEN]; + int len, nfiles = 0; + char **files = NULL; + struct stat sb; + + *n = 0; + *argv = NULL; + + FILE *fh = fopen(file_list,"r"); + if ( !fh ) + { + fprintf(stderr,"%s: %s\n", file_list,strerror(errno)); + return 1; + } + + files = (char**) calloc(nfiles,sizeof(char*)); + nfiles = 0; + while ( fgets(buf,MAX_PATH_LEN,fh) ) + { + // allow empty lines and trailing spaces + len = strlen(buf); + while ( len>0 && isspace(buf[len-1]) ) len--; + if ( !len ) continue; + + // check sanity of the file list + buf[len] = 0; + if (! (is_url(buf) || stat(buf, &sb) == 0)) + { + // no such file, check if it is safe to print its name + int i, safe_to_print = 1; + for (i=0; irflag_require); + char *tmp_filter = bam_flag2str(mplp->rflag_filter); + + // Display usage information, formatted for the standard 80 columns. + // (The unusual string formatting here aids the readability of this + // source code in 80 columns, to the extent that's possible.) + + fprintf(fp, +"\n" +"Usage: bcftools mpileup [options] in1.bam [in2.bam [...]]\n" +"\n" +"Input options:\n" +" -6, --illumina1.3+ quality is in the Illumina-1.3+ encoding\n" +" -A, --count-orphans do not discard anomalous read pairs\n" +" -b, --bam-list FILE list of input BAM filenames, one per line\n" +" -B, --no-BAQ disable BAQ (per-Base Alignment Quality)\n" +" -C, --adjust-MQ INT adjust mapping quality; recommended:50, disable:0 [0]\n" +" -d, --max-depth INT max per-file depth; avoids excessive memory usage [%d]\n", mplp->max_depth); + fprintf(fp, +" -E, --redo-BAQ recalculate BAQ on the fly, ignore existing BQs\n" +" -f, --fasta-ref FILE faidx indexed reference sequence file\n" +" --no-reference do not require fasta reference file\n" +" -G, --read-groups FILE select or exclude read groups listed in the file\n" +" -q, --min-MQ INT skip alignments with mapQ smaller than INT [%d]\n", mplp->min_mq); + fprintf(fp, +" -Q, --min-BQ INT skip bases with baseQ/BAQ smaller than INT [%d]\n", mplp->min_baseQ); + fprintf(fp, +" -r, --regions REG[,...] comma separated list of regions in which pileup is generated\n" +" -R, --regions-file FILE restrict to regions listed in a file\n" +" --ignore-RG ignore RG tags (one BAM = one sample)\n" +" --rf, --incl-flags STR|INT required flags: skip reads with mask bits unset [%s]\n", tmp_require); + fprintf(fp, +" --ff, --excl-flags STR|INT filter flags: skip reads with mask bits set\n" +" [%s]\n", tmp_filter); + fprintf(fp, +" -s, --samples LIST comma separated list of samples to include\n" +" -S, --samples-file FILE file of samples to include\n" +" -t, --targets REG[,...] similar to -r but streams rather than index-jumps\n" +" -T, --targets-file FILE similar to -R but streams rather than index-jumps\n" +" -x, --ignore-overlaps disable read-pair overlap detection\n" +"\n" +"Output options:\n" +" -a, --annotate LIST optional tags to output; '?' to list []\n" +" -g, --gvcf INT[,...] group non-variant sites into gVCF blocks according\n" +" to minimum per-sample DP\n" +" --no-version do not append version and command line to the header\n" +" -o, --output FILE write output to FILE [standard output]\n" +" -O, --output-type TYPE 'b' compressed BCF; 'u' uncompressed BCF;\n" +" 'z' compressed VCF; 'v' uncompressed VCF [v]\n" +" --threads INT number of extra output compression threads [0]\n" +"\n" +"SNP/INDEL genotype likelihoods options:\n" +" -e, --ext-prob INT Phred-scaled gap extension seq error probability [%d]\n", mplp->extQ); + fprintf(fp, +" -F, --gap-frac FLOAT minimum fraction of gapped reads [%g]\n", mplp->min_frac); + fprintf(fp, +" -h, --tandem-qual INT coefficient for homopolymer errors [%d]\n", mplp->tandemQ); + fprintf(fp, +" -I, --skip-indels do not perform indel calling\n" +" -L, --max-idepth INT maximum per-file depth for INDEL calling [%d]\n", mplp->max_indel_depth); + fprintf(fp, +" -m, --min-ireads INT minimum number gapped reads for indel candidates [%d]\n", mplp->min_support); + fprintf(fp, +" -o, --open-prob INT Phred-scaled gap open seq error probability [%d]\n", mplp->openQ); + fprintf(fp, +" -p, --per-sample-mF apply -m and -F per-sample for increased sensitivity\n" +" -P, --platforms STR comma separated list of platforms for indels [all]\n" +"\n" +"Notes: Assuming diploid individuals.\n" +"\n"); + + free(tmp_require); + free(tmp_filter); +} + +int bam_mpileup(int argc, char *argv[]) +{ + int c; + const char *file_list = NULL; + char **fn = NULL; + int nfiles = 0, use_orphan = 0, noref = 0; + mplp_conf_t mplp; + memset(&mplp, 0, sizeof(mplp_conf_t)); + mplp.min_baseQ = 13; + mplp.capQ_thres = 0; + mplp.max_depth = 250; mplp.max_indel_depth = 250; + mplp.openQ = 40; mplp.extQ = 20; mplp.tandemQ = 100; + mplp.min_frac = 0.002; mplp.min_support = 1; + mplp.flag = MPLP_NO_ORPHAN | MPLP_REALN | MPLP_SMART_OVERLAPS; + mplp.argc = argc; mplp.argv = argv; + mplp.rflag_filter = BAM_FUNMAP | BAM_FSECONDARY | BAM_FQCFAIL | BAM_FDUP; + mplp.output_fname = NULL; + mplp.output_type = FT_VCF; + mplp.record_cmd_line = 1; + mplp.n_threads = 0; + mplp.bsmpl = bam_smpl_init(); + + static const struct option lopts[] = + { + {"rf", required_argument, NULL, 1}, // require flag + {"ff", required_argument, NULL, 2}, // filter flag + {"incl-flags", required_argument, NULL, 1}, + {"excl-flags", required_argument, NULL, 2}, + {"output", required_argument, NULL, 3}, + {"open-prob", required_argument, NULL, 4}, + {"ignore-RG", no_argument, NULL, 5}, + {"ignore-rg", no_argument, NULL, 5}, + {"gvcf", required_argument, NULL, 'g'}, + {"non-reference", no_argument, NULL, 7}, + {"no-version", no_argument, NULL, 8}, + {"threads",required_argument,NULL,9}, + {"illumina1.3+", no_argument, NULL, '6'}, + {"count-orphans", no_argument, NULL, 'A'}, + {"bam-list", required_argument, NULL, 'b'}, + {"no-BAQ", no_argument, NULL, 'B'}, + {"no-baq", no_argument, NULL, 'B'}, + {"adjust-MQ", required_argument, NULL, 'C'}, + {"adjust-mq", required_argument, NULL, 'C'}, + {"max-depth", required_argument, NULL, 'd'}, + {"redo-BAQ", no_argument, NULL, 'E'}, + {"redo-baq", no_argument, NULL, 'E'}, + {"fasta-ref", required_argument, NULL, 'f'}, + {"read-groups", required_argument, NULL, 'G'}, + {"region", required_argument, NULL, 'r'}, + {"regions", required_argument, NULL, 'r'}, + {"regions-file", required_argument, NULL, 'R'}, + {"targets", required_argument, NULL, 't'}, + {"targets-file", required_argument, NULL, 'T'}, + {"min-MQ", required_argument, NULL, 'q'}, + {"min-mq", required_argument, NULL, 'q'}, + {"min-BQ", required_argument, NULL, 'Q'}, + {"min-bq", required_argument, NULL, 'Q'}, + {"ignore-overlaps", no_argument, NULL, 'x'}, + {"output-type", required_argument, NULL, 'O'}, + {"samples", required_argument, NULL, 's'}, + {"samples-file", required_argument, NULL, 'S'}, + {"annotate", required_argument, NULL, 'a'}, + {"ext-prob", required_argument, NULL, 'e'}, + {"gap-frac", required_argument, NULL, 'F'}, + {"tandem-qual", required_argument, NULL, 'h'}, + {"skip-indels", no_argument, NULL, 'I'}, + {"max-idepth", required_argument, NULL, 'L'}, + {"min-ireads ", required_argument, NULL, 'm'}, + {"per-sample-mF", no_argument, NULL, 'p'}, + {"per-sample-mf", no_argument, NULL, 'p'}, + {"platforms", required_argument, NULL, 'P'}, + {NULL, 0, NULL, 0} + }; + while ((c = getopt_long(argc, argv, "Ag:f:r:R:q:Q:C:Bd:L:b:P:po:e:h:Im:F:EG:6O:xa:s:S:t:T:",lopts,NULL)) >= 0) { + switch (c) { + case 'x': mplp.flag &= ~MPLP_SMART_OVERLAPS; break; + case 1 : + mplp.rflag_require = bam_str2flag(optarg); + if ( mplp.rflag_require<0 ) { fprintf(stderr,"Could not parse --rf %s\n", optarg); return 1; } + break; + case 2 : + mplp.rflag_filter = bam_str2flag(optarg); + if ( mplp.rflag_filter<0 ) { fprintf(stderr,"Could not parse --ff %s\n", optarg); return 1; } + break; + case 3 : mplp.output_fname = optarg; break; + case 4 : mplp.openQ = atoi(optarg); break; + case 5 : bam_smpl_ignore_readgroups(mplp.bsmpl); break; + case 'g': + mplp.gvcf = gvcf_init(optarg); + if ( !mplp.gvcf ) error("Could not parse: --gvcf %s\n", optarg); + break; + case 'f': + mplp.fai = fai_load(optarg); + if (mplp.fai == NULL) return 1; + mplp.fai_fname = optarg; + break; + case 7 : noref = 1; break; + case 8 : mplp.record_cmd_line = 0; break; + case 9 : mplp.n_threads = strtol(optarg, 0, 0); break; + case 'd': mplp.max_depth = atoi(optarg); break; + case 'r': mplp.reg_fname = strdup(optarg); break; + case 'R': mplp.reg_fname = strdup(optarg); mplp.reg_is_file = 1; break; + case 't': + // In the original version the whole BAM was streamed which is inefficient + // with few BED intervals and big BAMs. Todo: devise a heuristic to determine + // best strategy, that is streaming or jumping. + if ( optarg[0]=='^' ) optarg++; + else mplp.bed_logic = 1; + mplp.bed = regidx_init(NULL,regidx_parse_reg,NULL,0,NULL); + mplp.bed_itr = regitr_init(mplp.bed); + if ( regidx_insert_list(mplp.bed,optarg,',') !=0 ) + { + fprintf(stderr,"Could not parse the targets: %s\n", optarg); + exit(EXIT_FAILURE); + } + break; + case 'T': + if ( optarg[0]=='^' ) optarg++; + else mplp.bed_logic = 1; + mplp.bed = regidx_init(optarg,NULL,NULL,0,NULL); + if (!mplp.bed) { fprintf(stderr, "bcftools mpileup: Could not read file \"%s\"", optarg); return 1; } + break; + case 'P': mplp.pl_list = strdup(optarg); break; + case 'p': mplp.flag |= MPLP_PER_SAMPLE; break; + case 'B': mplp.flag &= ~MPLP_REALN; break; + case 'I': mplp.flag |= MPLP_NO_INDEL; break; + case 'E': mplp.flag |= MPLP_REDO_BAQ; break; + case '6': mplp.flag |= MPLP_ILLUMINA13; break; + case 's': if ( bam_smpl_add_samples(mplp.bsmpl,optarg,0)<0 ) error("Could not read samples: %s\n",optarg); break; + case 'S': if ( bam_smpl_add_samples(mplp.bsmpl,optarg,1)<0 ) error("Could not read samples: %s\n",optarg); break; + case 'O': + switch (optarg[0]) { + case 'b': mplp.output_type = FT_BCF_GZ; break; + case 'u': mplp.output_type = FT_BCF; break; + case 'z': mplp.output_type = FT_VCF_GZ; break; + case 'v': mplp.output_type = FT_VCF; break; + default: error("[error] The option \"-O\" changed meaning when mpileup moved to bcftools. Did you mean: \"bcftools mpileup --output-type\" or \"samtools mpileup --output-BP\"?\n", optarg); + } + break; + case 'C': mplp.capQ_thres = atoi(optarg); break; + case 'q': mplp.min_mq = atoi(optarg); break; + case 'Q': mplp.min_baseQ = atoi(optarg); break; + case 'b': file_list = optarg; break; + case 'o': { + char *end; + long value = strtol(optarg, &end, 10); + // Distinguish between -o INT and -o FILE (a bit of a hack!) + if (*end == '\0') mplp.openQ = value; + else mplp.output_fname = optarg; + } + break; + case 'e': mplp.extQ = atoi(optarg); break; + case 'h': mplp.tandemQ = atoi(optarg); break; + case 'A': use_orphan = 1; break; + case 'F': mplp.min_frac = atof(optarg); break; + case 'm': mplp.min_support = atoi(optarg); break; + case 'L': mplp.max_indel_depth = atoi(optarg); break; + case 'G': bam_smpl_add_readgroups(mplp.bsmpl, optarg, 1); break; + case 'a': + if (optarg[0]=='?') { + list_annotations(stderr); + return 1; + } + mplp.fmt_flag |= parse_format_flag(optarg); + break; + default: + fprintf(stderr,"Invalid option: '%c'\n", c); + return 1; + } + } + + if ( mplp.gvcf && !(mplp.fmt_flag&B2B_FMT_DP) ) + { + fprintf(stderr,"[warning] The -t DP option is required with --gvcf, switching on.\n"); + mplp.fmt_flag |= B2B_FMT_DP; + } + if ( mplp.flag&(MPLP_BCF|MPLP_VCF|MPLP_NO_COMP) ) + { + if ( mplp.flag&MPLP_VCF ) + { + if ( mplp.flag&MPLP_NO_COMP ) mplp.output_type = FT_VCF; + else mplp.output_type = FT_VCF_GZ; + } + else if ( mplp.flag&MPLP_BCF ) + { + if ( mplp.flag&MPLP_NO_COMP ) mplp.output_type = FT_BCF; + else mplp.output_type = FT_BCF_GZ; + } + } + if ( !(mplp.flag&MPLP_REALN) && mplp.flag&MPLP_REDO_BAQ ) + { + fprintf(stderr,"Error: The -B option cannot be combined with -E\n"); + return 1; + } + if (use_orphan) mplp.flag &= ~MPLP_NO_ORPHAN; + if (argc == 1) + { + print_usage(stderr, &mplp); + return 1; + } + if (!mplp.fai && !noref) { + fprintf(stderr,"Error: mpileup requires the --fasta-ref option by default; use --no-reference to run without a fasta reference\n"); + return 1; + } + int ret,i; + if (file_list) + { + if ( read_file_list(file_list,&nfiles,&fn) ) return 1; + mplp.files = fn; + mplp.nfiles = nfiles; + } + else + { + mplp.nfiles = argc - optind; + mplp.files = (char**) malloc(mplp.nfiles*sizeof(char*)); + for (i=0; i + + Permission is hereby granted, free of charge, to any person obtaining a copy + of this software and associated documentation files (the "Software"), to deal + in the Software without restriction, including without limitation the rights + to use, copy, modify, merge, publish, distribute, sublicense, and/or sell + copies of the Software, and to permit persons to whom the Software is + furnished to do so, subject to the following conditions: + + The above copyright notice and this permission notice shall be included in + all copies or substantial portions of the Software. + + THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR + IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, + FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE + AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER + LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, + OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN + THE SOFTWARE. +*/ + +// Code to build this table is below +#ifdef BUILD_MW +#include + +double mann_whitney_1947(int n, int m, int U) +{ + if (U<0) return 0; + if (n==0||m==0) return U==0 ? 1 : 0; + return (double)n/(n+m)*mann_whitney_1947(n-1,m,U-m) + (double)m/(n+m)*mann_whitney_1947(n,m-1,U); +} + +int main(void) { + int i, j, k; + printf("static double mw[6][6][50] = // [2-7][2-7][0-49]\n{\n"); + for (i = 2; i < 8; i++) { + printf(" {\n"); + for (j = 2; j < 8; j++) { + printf(" {\n"); + for (k = 0; k < 50; k++) { + printf(" %.17f,\n", mann_whitney_1947(i,j,k)); + } + printf(" },\n"); + } + printf(" },\n"); + } + printf("};\n"); + return 0; +} +#endif + +static double mw[6][6][50] = // [2-7][2-7][0-49] +{ + { + { + 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b/peakfit.c new file mode 100644 index 0000000..8094b5d --- /dev/null +++ b/peakfit.c @@ -0,0 +1,605 @@ +/* The MIT License + + Copyright (c) 2013-2015 Genome Research Ltd. + + Author: Petr Danecek + + Permission is hereby granted, free of charge, to any person obtaining a copy + of this software and associated documentation files (the "Software"), to deal + in the Software without restriction, including without limitation the rights + to use, copy, modify, merge, publish, distribute, sublicense, and/or sell + copies of the Software, and to permit persons to whom the Software is + furnished to do so, subject to the following conditions: + + The above copyright notice and this permission notice shall be included in + all copies or substantial portions of the Software. + + THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR + IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, + FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE + AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER + LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, + OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN + THE SOFTWARE. + + */ + +#include "peakfit.h" +#include +#include +#include +#include +#include +#include +#include +#include + +#define NPARAMS 5 + +// gauss params: sqrt(scale), center, sigma +typedef struct _peak_t +{ + int fit_mask; + double params[NPARAMS], ori_params[NPARAMS]; // current and input parameters + struct { int scan; double min, max, best; } mc[NPARAMS]; // monte-carlo settings and best parameter + void (*calc_f) (int nvals, double *xvals, double *yvals, void *args); + void (*calc_df) (int nvals, double *xvals, double *yvals, double *dfvals, int idf, void *args); + void (*print_func) (struct _peak_t *pk, kstring_t *str); + void (*convert_get) (struct _peak_t *pk, double *params); + double (*convert_set) (struct _peak_t *pk, int iparam, double value); +} +peak_t; + +struct _peakfit_t +{ + int npeaks, mpeaks, nparams, mparams; + peak_t *peaks; + double *params; + int nvals, mvals; + double *xvals, *yvals, *vals; + kstring_t str; + int verbose, nmc_iter; +}; + + +/* + Gaussian peak with the center bound in the interval : + yi = scale^2 * exp(-(xi-z)^2/sigma^2) + + dy/dscale = 2*scale * EXP + dy/dcenter = -scale^2 * sin(center) * (e-d) * (xi - z) * EXP / sigma^2 + dy/dsigma = 2*scale^2 * (xi - z)^2 * EXP / sigma^3 + + where + z = 0.5*(cos(center)+1)*(e-d) + d + EXP = exp(-(xi-z)^2/sigma^2) +*/ +void bounded_gaussian_calc_f(int nvals, double *xvals, double *yvals, void *args) +{ + peak_t *pk = (peak_t*) args; + + double scale2 = pk->params[0] * pk->params[0]; + double center = pk->params[1]; + double sigma = pk->params[2]; + double d = pk->params[3]; + double e = pk->params[4]; + double z = 0.5*(cos(center)+1)*(e-d) + d; + + int i; + for (i=0; iparams[0]; + double center = pk->params[1]; + double sigma = pk->params[2]; + double d = pk->params[3]; + double e = pk->params[4]; + double z = 0.5*(cos(center)+1)*(e-d) + d; + + int i; + for (i=0; iparams[1]; + double d = pk->params[3]; + double e = pk->params[4]; + double z = 0.5*(cos(center)+1)*(e-d) + d; + ksprintf(str,"%f**2 * exp(-(x-%f)**2/%f**2)",fabs(pk->params[0]),z,fabs(pk->params[2])); +} +double bounded_gaussian_convert_set(peak_t *pk, int iparam, double value) +{ + if ( iparam!=1 ) return value; + double d = pk->ori_params[3]; + double e = pk->ori_params[4]; + if ( valuee ) value = e; + return acos(2*(value-d)/(e-d) - 1); +} +void bounded_gaussian_convert_get(peak_t *pk, double *params) +{ + params[0] = fabs(pk->params[0]); + params[2] = fabs(pk->params[2]); + double center = pk->params[1]; + double d = pk->params[3]; + double e = pk->params[4]; + params[1] = 0.5*(cos(center)+1)*(e-d) + d; +} + +void peakfit_add_bounded_gaussian(peakfit_t *pkf, double a, double b, double c, double d, double e, int fit_mask) +{ + pkf->npeaks++; + hts_expand0(peak_t,pkf->npeaks,pkf->mpeaks,pkf->peaks); + + int i, nfit = 0; + for (i=0; inparams += nfit; + hts_expand0(double,pkf->nparams,pkf->mparams,pkf->params); + + peak_t *pk = &pkf->peaks[pkf->npeaks-1]; + memset(pk, 0, sizeof(peak_t)); + + pk->calc_f = bounded_gaussian_calc_f; + pk->calc_df = bounded_gaussian_calc_df; + pk->print_func = bounded_gaussian_sprint_func; + pk->convert_set = bounded_gaussian_convert_set; + pk->convert_get = bounded_gaussian_convert_get; + pk->fit_mask = fit_mask; + pk->ori_params[0] = a; + pk->ori_params[2] = c; + pk->ori_params[3] = d; + pk->ori_params[4] = e; + pk->ori_params[1] = pk->convert_set(pk, 1, b); +} + + +/* + Gaussian peak: + yi = scale^2 * exp(-(x-center)^2/sigma^2) + + dy/dscale = 2 * scale * EXP + dy/dcenter = 2 * scale^2 * (x-center) * EXP / sigma^2 + dy/dsigma = 2 * scale^2 * (x-center)^2 * EXP / sigma^3 + + where + EXP = exp(-(x-center)^2/sigma^2) +*/ +void gaussian_calc_f(int nvals, double *xvals, double *yvals, void *args) +{ + peak_t *pk = (peak_t*) args; + + double scale2 = pk->params[0] * pk->params[0]; + double center = pk->params[1]; + double sigma = pk->params[2]; + + int i; + for (i=0; iparams[0]; + double center = pk->params[1]; + double sigma = pk->params[2]; + + int i; + for (i=0; iparams[0]),pk->params[1],fabs(pk->params[2])); +} +void gaussian_convert_get(peak_t *pk, double *params) +{ + params[0] = fabs(pk->params[0]); + params[1] = fabs(pk->params[1]); + params[2] = fabs(pk->params[2]); +} + + +void peakfit_add_gaussian(peakfit_t *pkf, double a, double b, double c, int fit_mask) +{ + pkf->npeaks++; + hts_expand0(peak_t,pkf->npeaks,pkf->mpeaks,pkf->peaks); + + int i, nfit = 0; + for (i=0; inparams += nfit; + hts_expand0(double,pkf->nparams,pkf->mparams,pkf->params); + + peak_t *pk = &pkf->peaks[pkf->npeaks-1]; + memset(pk, 0, sizeof(peak_t)); + + pk->calc_f = gaussian_calc_f; + pk->calc_df = gaussian_calc_df; + pk->print_func = gaussian_sprint_func; + pk->convert_get = gaussian_convert_get; + pk->fit_mask = fit_mask; + pk->ori_params[0] = a; + pk->ori_params[1] = b; + pk->ori_params[2] = c; +} + + +/* + exp peak: + yi = scale^2 * exp((x-center)/sigma^2) + + dy/dscale = 2 * scale * EXP + dy/dcenter = -scale^2 * EXP / sigma^2 + dy/dsigma = -2 * scale^2 * (x-center) * EXP / sigma^3 + + where + EXP = exp((x-center)/sigma^2) +*/ +void exp_calc_f(int nvals, double *xvals, double *yvals, void *args) +{ + peak_t *pk = (peak_t*) args; + + double scale2 = pk->params[0] * pk->params[0]; + double center = pk->params[1]; + double sigma = pk->params[2]; + + int i; + for (i=0; iparams[0]; + double center = pk->params[1]; + double sigma = pk->params[2]; + + int i; + for (i=0; iparams[0]),pk->params[1],fabs(pk->params[2])); +} +void exp_convert_get(peak_t *pk, double *params) +{ + params[0] = fabs(pk->params[0]); + params[1] = fabs(pk->params[1]); + params[2] = fabs(pk->params[2]); +} + +void peakfit_add_exp(peakfit_t *pkf, double a, double b, double c, int fit_mask) +{ + pkf->npeaks++; + hts_expand0(peak_t,pkf->npeaks,pkf->mpeaks,pkf->peaks); + + int i, nfit = 0; + for (i=0; inparams += nfit; + hts_expand0(double,pkf->nparams,pkf->mparams,pkf->params); + + peak_t *pk = &pkf->peaks[pkf->npeaks-1]; + memset(pk, 0, sizeof(peak_t)); + + pk->calc_f = exp_calc_f; + pk->calc_df = exp_calc_df; + pk->print_func = exp_sprint_func; + pk->convert_get = exp_convert_get; + pk->fit_mask = fit_mask; + pk->ori_params[0] = a; + pk->ori_params[1] = b; + pk->ori_params[2] = c; +} + + +void peakfit_set_params(peakfit_t *pkf, int ipk, double *params, int nparams) +{ + peak_t *pk = &pkf->peaks[ipk]; + int i; + if ( pk->convert_set ) + for (i=0; iparams[i] = pk->convert_set(pk, i, params[i]); + else + for (i=0; iparams[i] = params[i]; +} + +void peakfit_get_params(peakfit_t *pkf, int ipk, double *params, int nparams) +{ + peak_t *pk = &pkf->peaks[ipk]; + if ( pk->convert_get ) pk->convert_get(pk, params); + else + { + int i; + for (i=0; iparams[i]; + } +} + +peakfit_t *peakfit_init(void) +{ + return (peakfit_t*)calloc(1,sizeof(peakfit_t)); +} + +void peakfit_reset(peakfit_t *pkf) +{ + pkf->npeaks = pkf->nparams = 0; + memset(pkf->peaks,0,sizeof(peak_t)*pkf->mpeaks); +} + +void peakfit_destroy(peakfit_t *pkf) +{ + free(pkf->str.s); + free(pkf->vals); + free(pkf->params); + free(pkf->peaks); + free(pkf); +} + +int peakfit_calc_f(const gsl_vector *params, void *data, gsl_vector *yvals) +{ + peakfit_t *pkf = (peakfit_t *) data; + + int i,j; + for (i=0; invals; i++) + pkf->vals[i] = 0; + + int iparam = 0; + for (i=0; inpeaks; i++) + { + peak_t *pk = &pkf->peaks[i]; + for (j=0; jfit_mask & (1<params[j] = gsl_vector_get(params,iparam); + iparam++; + } + pk->calc_f(pkf->nvals, pkf->xvals, pkf->vals, pk); + } + + for (i=0; invals; i++) + gsl_vector_set(yvals, i, (pkf->vals[i] - pkf->yvals[i])/0.01); + + return GSL_SUCCESS; +} +int peakfit_calc_df(const gsl_vector *params, void *data, gsl_matrix *jacobian) +{ + peakfit_t *pkf = (peakfit_t *) data; + + int i,j,k,iparam = 0; + for (i=0; inpeaks; i++) + { + peak_t *pk = &pkf->peaks[i]; + int iparam_prev = iparam; + for (j=0; jfit_mask & (1<params[j] = gsl_vector_get(params,iparam); + iparam++; + } + iparam = iparam_prev; + for (j=0; jfit_mask & (1<nvals; k++) pkf->vals[k] = 0; + pk->calc_df(pkf->nvals, pkf->xvals, pkf->yvals, pkf->vals, j, pk); + for (k=0; knvals; k++) gsl_matrix_set(jacobian, k, iparam, pkf->vals[k]); + iparam++; + } + } + return GSL_SUCCESS; +} +int peakfit_calc_fdf(const gsl_vector *params, void *data, gsl_vector *yvals, gsl_matrix *jacobian) +{ + peakfit_calc_f(params, data, yvals); + peakfit_calc_df(params, data, jacobian); + return GSL_SUCCESS; +} + +double peakfit_evaluate(peakfit_t *pkf) +{ + int i; + for (i=0; invals; i++) + pkf->vals[i] = 0; + + for (i=0; inpeaks; i++) + pkf->peaks[i].calc_f(pkf->nvals, pkf->xvals, pkf->vals, &pkf->peaks[i]); + + double sum = 0; + for (i=0; invals; i++) + sum += fabs(pkf->vals[i] - pkf->yvals[i]); + + return sum; +} + +const char *peakfit_sprint_func(peakfit_t *pkf) +{ + pkf->str.l = 0; + int i; + for (i=0; inpeaks; i++) + { + if ( i>0 ) kputs(" + ", &pkf->str); + pkf->peaks[i].print_func(&pkf->peaks[i], &pkf->str); + } + return (const char*)pkf->str.s; +} + +void peakfit_verbose(peakfit_t *pkf, int level) +{ + pkf->verbose = level; +} + +void peakfit_set_mc(peakfit_t *pkf, double xmin, double xmax, int iparam, int niter) +{ + peak_t *pk = &pkf->peaks[ pkf->npeaks-1 ]; + pk->mc[iparam].scan = 1; + pk->mc[iparam].min = xmin; + pk->mc[iparam].max = xmax; + pkf->nmc_iter = niter; +} + +double peakfit_run(peakfit_t *pkf, int nvals, double *xvals, double *yvals) +{ + srand(0); // for reproducibility + + pkf->nvals = nvals; + pkf->xvals = xvals; + pkf->yvals = yvals; + hts_expand0(double,pkf->nvals,pkf->mvals,pkf->vals); + if ( !pkf->nparams ) return peakfit_evaluate(pkf); + + gsl_multifit_function_fdf mfunc; + mfunc.f = &peakfit_calc_f; + mfunc.df = &peakfit_calc_df; + mfunc.fdf = &peakfit_calc_fdf; + mfunc.n = nvals; + mfunc.p = pkf->nparams; + mfunc.params = pkf; + + const gsl_multifit_fdfsolver_type *solver_type; + gsl_multifit_fdfsolver *solver; + solver_type = gsl_multifit_fdfsolver_lmsder; + solver = gsl_multifit_fdfsolver_alloc(solver_type, nvals, mfunc.p); + gsl_vector *grad = gsl_vector_alloc(pkf->nparams); + + int imc_iter, i,j, iparam; + double best_fit = HUGE_VAL; + for (imc_iter=0; imc_iter<=pkf->nmc_iter; imc_iter++) // possibly multiple monte-carlo iterations + { + // set GSL parameters + iparam = 0; + for (i=0; inpeaks; i++) + { + peak_t *pk = &pkf->peaks[i]; + for (j=0; jparams[j] = pk->ori_params[j]; + if ( pk->mc[j].scan ) + { + pk->params[j] = rand()*(pk->mc[j].max - pk->mc[j].min)/RAND_MAX + pk->mc[j].min; + if ( pk->convert_set ) pk->params[j] = pk->convert_set(pk, j, pk->params[j]); + } + if ( !(pk->fit_mask & (1<params[iparam] = pk->params[j]; + iparam++; + } + } + + gsl_vector_view vview = gsl_vector_view_array(pkf->params, mfunc.p); + gsl_multifit_fdfsolver_set(solver, &mfunc, &vview.vector); + + // iterate until convergence (or lack of it) + int ret, test1 = 0, test2 = 0, niter = 0, niter_max = 500; + do + { + ret = gsl_multifit_fdfsolver_iterate(solver); + if ( pkf->verbose >1 ) + { + fprintf(stderr, "%d: ", niter); + for (i=0; inpeaks; i++) + { + peak_t *pk = &pkf->peaks[i]; + fprintf(stderr,"\t%f %f %f", pk->params[0],pk->params[1],pk->params[2]); + } + fprintf(stderr, "\t.. %s\n", gsl_strerror(ret)); + } + if ( ret ) break; + +#if GSL_MAJOR_VERSION >= 2 + int info; + test1 = gsl_multifit_fdfsolver_test(solver, 1e-8,1e-8, 0.0, &info); +#else + gsl_multifit_gradient(solver->J, solver->f, grad); + test1 = gsl_multifit_test_gradient(grad, 1e-8); + test2 = gsl_multifit_test_delta(solver->dx, solver->x, 1e-8, 1e-8); +#endif + } + while ((test1==GSL_CONTINUE || test2==GSL_CONTINUE) && ++niterverbose >1 ) + { + fprintf(stderr,"test1=%s\n", gsl_strerror(test1)); + fprintf(stderr,"test2=%s\n", gsl_strerror(test2)); + } + + // recover parameters + iparam = 0; + for (i=0; inpeaks; i++) + { + peak_t *pk = &pkf->peaks[i]; + for (j=0; jfit_mask & (1<params[j] = gsl_vector_get(solver->x, iparam++); + } + } + + // evaluate fit, update best parameters + double fit = peakfit_evaluate(pkf); + if ( fitnpeaks; i++) + { + peak_t *pk = &pkf->peaks[i]; + for (j=0; jmc[j].best = pk->params[j]; + } + } + if ( fitnpeaks; i++) + { + peak_t *pk = &pkf->peaks[i]; + for (j=0; jparams[j] = pk->mc[j].best; + } + return best_fit; +} + + diff --git a/peakfit.h b/peakfit.h new file mode 100644 index 0000000..8a9e4fa --- /dev/null +++ b/peakfit.h @@ -0,0 +1,49 @@ +/* The MIT License + + Copyright (c) 2013-2015 Genome Research Ltd. + + Author: Petr Danecek + + Permission is hereby granted, free of charge, to any person obtaining a copy + of this software and associated documentation files (the "Software"), to deal + in the Software without restriction, including without limitation the rights + to use, copy, modify, merge, publish, distribute, sublicense, and/or sell + copies of the Software, and to permit persons to whom the Software is + furnished to do so, subject to the following conditions: + + The above copyright notice and this permission notice shall be included in + all copies or substantial portions of the Software. + + THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR + IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, + FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE + AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER + LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, + OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN + THE SOFTWARE. + + */ + +#ifndef PEAKFIT_H +#define PEAKFIT_H + +typedef struct _peakfit_t peakfit_t; + +peakfit_t *peakfit_init(void); +void peakfit_reset(peakfit_t *pkf); +void peakfit_destroy(peakfit_t *pkf); + +void peakfit_add_gaussian(peakfit_t *pkf, double a, double b, double c, int fit_mask); +void peakfit_add_bounded_gaussian(peakfit_t *pkf, double a, double b, double c, double d, double e, int fit_mask); +void peakfit_add_exp(peakfit_t *pkf, double a, double b, double c, int fit_mask); +void peakfit_set_mc(peakfit_t *pkf, double xmin, double xmax, int iparam, int niter); +double peakfit_run(peakfit_t *pkf, int nvals, double *xvals, double *yvals); +double peakfit_evaluate(peakfit_t *pkf); + +void peakfit_verbose(peakfit_t *pkf, int level); +void peakfit_get_params(peakfit_t *pkf, int ipk, double *params, int nparams); +void peakfit_set_params(peakfit_t *pkf, int ipk, double *params, int nparams); +const char *peakfit_sprint_func(peakfit_t *pkf); + +#endif + diff --git a/ploidy.c b/ploidy.c new file mode 100644 index 0000000..550ba87 --- /dev/null +++ b/ploidy.c @@ -0,0 +1,268 @@ +/* + Copyright (C) 2014-2016 Genome Research Ltd. + + Author: Petr Danecek + + Permission is hereby granted, free of charge, to any person obtaining a copy + of this software and associated documentation files (the "Software"), to deal + in the Software without restriction, including without limitation the rights + to use, copy, modify, merge, publish, distribute, sublicense, and/or sell + copies of the Software, and to permit persons to whom the Software is + furnished to do so, subject to the following conditions: + + The above copyright notice and this permission notice shall be included in + all copies or substantial portions of the Software. + + THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR + IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, + FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE + AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER + LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, + OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN + THE SOFTWARE. +*/ + +#include +#include +#include +#include "bcftools.h" +#include "ploidy.h" + +struct _ploidy_t +{ + int nsex, msex; // number of genders, m:number of allocated elements in id2sex array + int dflt, min, max; // ploidy: default, min and max (only explicitly listed) + int *sex2dflt; + regidx_t *idx; + regitr_t *itr; + void *sex2id; + char **id2sex; + kstring_t tmp_str; +}; + +typedef struct +{ + int sex, ploidy; +} +sex_ploidy_t; + + +regidx_t *ploidy_regions(ploidy_t *ploidy) +{ + return ploidy->idx; +} + +int ploidy_parse(const char *line, char **chr_beg, char **chr_end, uint32_t *beg, uint32_t *end, void *payload, void *usr) +{ + int i, ret; + ploidy_t *ploidy = (ploidy_t*) usr; + void *sex2id = ploidy->sex2id; + + // Check for special case of default ploidy "* * * " + int default_ploidy_def = 0; + + char *ss = (char*) line; + while ( *ss && isspace(*ss) ) ss++; + if ( ss[0]=='*' && (!ss[1] || isspace(ss[1])) ) + default_ploidy_def = 1; // definition of default ploidy, chr="*" + else + { + // Fill CHR,FROM,TO + ret = regidx_parse_tab(line,chr_beg,chr_end,beg,end,NULL,NULL); + if ( ret!=0 ) return ret; + } + + // Skip the fields already parsed by regidx_parse_tab + ss = (char*) line; + while ( *ss && isspace(*ss) ) ss++; + for (i=0; i<3; i++) + { + while ( *ss && !isspace(*ss) ) ss++; + if ( !*ss ) return -2; // wrong number of fields + while ( *ss && isspace(*ss) ) ss++; + } + if ( !*ss ) return -2; + + // Parse the payload + char *se = ss; + while ( *se && !isspace(*se) ) se++; + if ( !*se || se==ss ) error("Could not parse: %s\n", line); + ploidy->tmp_str.l = 0; + kputsn(ss,se-ss,&ploidy->tmp_str); + + sex_ploidy_t *sp = (sex_ploidy_t*) payload; + if ( khash_str2int_get(sex2id, ploidy->tmp_str.s, &sp->sex) != 0 ) + { + ploidy->nsex++; + hts_expand0(char*,ploidy->nsex,ploidy->msex,ploidy->id2sex); + ploidy->id2sex[ploidy->nsex-1] = strdup(ploidy->tmp_str.s); + sp->sex = khash_str2int_inc(ploidy->sex2id, ploidy->id2sex[ploidy->nsex-1]); + ploidy->sex2dflt = (int*) realloc(ploidy->sex2dflt,sizeof(int)*ploidy->nsex); + ploidy->sex2dflt[ploidy->nsex-1] = -1; + } + + ss = se; + while ( *se && isspace(*se) ) se++; + if ( !*se ) error("Could not parse: %s\n", line); + sp->ploidy = strtol(ss,&se,10); + if ( ss==se ) error("Could not parse: %s\n", line); + if ( ploidy->min<0 || sp->ploidy < ploidy->min ) ploidy->min = sp->ploidy; + if ( ploidy->max<0 || sp->ploidy > ploidy->max ) ploidy->max = sp->ploidy; + + // Special case, chr="*" stands for a default value + if ( default_ploidy_def ) + { + ploidy->sex2dflt[ploidy->nsex-1] = sp->ploidy; + return -1; + } + + return 0; +} + +static void _set_defaults(ploidy_t *ploidy, int dflt) +{ + int i; + if ( khash_str2int_get(ploidy->sex2id, "*", &i) == 0 ) dflt = ploidy->sex2dflt[i]; + for (i=0; insex; i++) + if ( ploidy->sex2dflt[i]==-1 ) ploidy->sex2dflt[i] = dflt; + + ploidy->dflt = dflt; + if ( ploidy->min<0 || dflt < ploidy->min ) ploidy->min = dflt; + if ( ploidy->max<0 || dflt > ploidy->max ) ploidy->max = dflt; +} + +ploidy_t *ploidy_init(const char *fname, int dflt) +{ + ploidy_t *pld = (ploidy_t*) calloc(1,sizeof(ploidy_t)); + if ( !pld ) return NULL; + + pld->min = pld->max = -1; + pld->sex2id = khash_str2int_init(); + pld->idx = regidx_init(fname,ploidy_parse,NULL,sizeof(sex_ploidy_t),pld); + if ( !pld->idx ) + { + ploidy_destroy(pld); + return NULL; + } + pld->itr = regitr_init(pld->idx); + _set_defaults(pld,dflt); + return pld; +} + +ploidy_t *ploidy_init_string(const char *str, int dflt) +{ + ploidy_t *pld = (ploidy_t*) calloc(1,sizeof(ploidy_t)); + if ( !pld ) return NULL; + + pld->min = pld->max = -1; + pld->sex2id = khash_str2int_init(); + pld->idx = regidx_init(NULL,ploidy_parse,NULL,sizeof(sex_ploidy_t),pld); + pld->itr = regitr_init(pld->idx); + + kstring_t tmp = {0,0,0}; + const char *ss = str; + while ( *ss ) + { + while ( *ss && isspace(*ss) ) ss++; + const char *se = ss; + while ( *se && *se!='\r' && *se!='\n' ) se++; + tmp.l = 0; + kputsn(ss, se-ss, &tmp); + regidx_insert(pld->idx,tmp.s); + while ( *se && isspace(*se) ) se++; + ss = se; + } + free(tmp.s); + + _set_defaults(pld,dflt); + return pld; +} + +void ploidy_destroy(ploidy_t *ploidy) +{ + if ( ploidy->sex2id ) khash_str2int_destroy_free(ploidy->sex2id); + if ( ploidy->itr ) regitr_destroy(ploidy->itr); + if ( ploidy->idx ) regidx_destroy(ploidy->idx); + free(ploidy->id2sex); + free(ploidy->tmp_str.s); + free(ploidy->sex2dflt); + free(ploidy); +} + +int ploidy_query(ploidy_t *ploidy, char *seq, int pos, int *sex2ploidy, int *min, int *max) +{ + int i, ret = regidx_overlap(ploidy->idx, seq,pos,pos, ploidy->itr); + + if ( !sex2ploidy && !min && !max ) return ret; + + if ( !ret ) + { + // no overlap + if ( min ) *min = ploidy->dflt; + if ( max ) *max = ploidy->dflt; + if ( sex2ploidy ) + for (i=0; insex; i++) sex2ploidy[i] = ploidy->sex2dflt[i]; + return 0; + } + + int _min = INT_MAX, _max = -1; + if ( sex2ploidy ) for (i=0; insex; i++) sex2ploidy[i] = ploidy->dflt; + + while ( regitr_overlap(ploidy->itr) ) + { + int sex = regitr_payload(ploidy->itr,sex_ploidy_t).sex; + int pld = regitr_payload(ploidy->itr,sex_ploidy_t).ploidy; + if ( pld!=ploidy->dflt ) + { + if ( sex2ploidy ) sex2ploidy[ sex ] = pld; + if ( _min > pld ) _min = pld; + if ( _max < pld ) _max = pld; + } + } + if ( _max==-1 ) _max = _min = ploidy->dflt; + if ( max ) *max = _max; + if ( min ) *min = _min; + + return 1; +} + +int ploidy_nsex(ploidy_t *ploidy) +{ + return ploidy->nsex; +} + +char *ploidy_id2sex(ploidy_t *ploidy, int id) +{ + if ( id<0 || id>=ploidy->nsex ) return NULL; + return ploidy->id2sex[id]; +} + +int ploidy_sex2id(ploidy_t *ploidy, char *sex) +{ + int id; + if ( khash_str2int_get(ploidy->sex2id,sex,&id)!=0 ) return -1; + return id; +} + +int ploidy_add_sex(ploidy_t *ploidy, const char *sex) +{ + int id; + if ( khash_str2int_get(ploidy->sex2id, sex, &id)==0 ) return id; + ploidy->nsex++; + hts_expand0(char*,ploidy->nsex,ploidy->msex,ploidy->id2sex); + ploidy->id2sex[ploidy->nsex-1] = strdup(sex); + ploidy->sex2dflt = (int*) realloc(ploidy->sex2dflt,sizeof(int)*ploidy->nsex); + ploidy->sex2dflt[ploidy->nsex-1] = ploidy->dflt; + return khash_str2int_inc(ploidy->sex2id, ploidy->id2sex[ploidy->nsex-1]); +} + +int ploidy_max(ploidy_t *ploidy) +{ + return ploidy->dflt > ploidy->max ? ploidy->dflt : ploidy->max; +} + +int ploidy_min(ploidy_t *ploidy) +{ + return ploidy->dflt < ploidy->min ? ploidy->dflt : ploidy->min; +} + diff --git a/ploidy.h b/ploidy.h new file mode 100644 index 0000000..1e7d2f7 --- /dev/null +++ b/ploidy.h @@ -0,0 +1,129 @@ +/* + Copyright (C) 2014 Genome Research Ltd. + + Author: Petr Danecek + + Permission is hereby granted, free of charge, to any person obtaining a copy + of this software and associated documentation files (the "Software"), to deal + in the Software without restriction, including without limitation the rights + to use, copy, modify, merge, publish, distribute, sublicense, and/or sell + copies of the Software, and to permit persons to whom the Software is + furnished to do so, subject to the following conditions: + + The above copyright notice and this permission notice shall be included in + all copies or substantial portions of the Software. + + THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR + IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, + FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE + AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER + LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, + OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN + THE SOFTWARE. +*/ + +/* + Lookup from region and sex to ploidy. + + Example of usage: + + int default_ploidy = 2; + ploidy_t *pld = ploidy_init(fname, default_ploidy); + + int nsex = ploidy_nsex(pld); + int *sex2ploidy = malloc(sizeof(int)*nsex); + + ploidy_query(pld, "X",60000, sex2ploidy, NULL, NULL); + for (i=0; i + +Permission is hereby granted, free of charge, to any person obtaining a copy +of this software and associated documentation files (the "Software"), to deal +in the Software without restriction, including without limitation the rights +to use, copy, modify, merge, publish, distribute, sublicense, and/or sell +copies of the Software, and to permit persons to whom the Software is +furnished to do so, subject to the following conditions: + +The above copyright notice and this permission notice shall be included in +all copies or substantial portions of the Software. + +THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL +THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER +LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING +FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER +DEALINGS IN THE SOFTWARE. */ + +#include +#include +#include +#include +#include +#include + +#include +#include +#include +KHASH_MAP_INIT_INT(gts2smps, uint32_t) + +#include "bcftools.h" + +/*! + * Flag definitions for args.flag + */ +#define MISSING (1<<0) +#define VERBOSE (1<<1) +#define SMPORDER (1<<2) + +typedef struct _args_t +{ + bcf_srs_t *file; /*! multi-sample VCF file */ + bcf_hdr_t *hdr; /*! VCF file header */ + FILE *out; /*! output file pointer */ + int nsmp; /*! number of samples, can be determined from header but is needed in multiple contexts */ + int nsmpp2; /*! 2^(nsmp) (is needed multiple times) */ + int *gt_arr; /*! temporary array, to store GTs of current line/record */ + int ngt_arr; /*! hold the number of current GT array entries */ + uint32_t *bankers; /*! array to store banker's sequence for all possible sample subsets for + programmatic indexing into smp_is for output printing, e.g. for three + samples A, B and C this would be the following order: + [ C, B, A, CB, CA, BA, CBA ] + [ 100, 010, 001, 110, 101, 011, 111 ] + */ + uint64_t *quick; /*! array to store n choose k lookup table of choose() function */ + uint8_t flag; /*! several flags, for positions see above*/ + uint64_t *missing_gts; /*! array to count missing genotypes of each sample */ + uint64_t *smp_is; /*! array to track all possible intersections between + samples, with each bit in the index integer belonging to one + sample. E.g. for three samples A, B and C, count would be in + the following order: + [ A, B, AB, C, AC, BC, ABC ] + [ 001, 010, 011, 100, 101, 110, 111 ] + */ +} +args_t; + +static args_t args; +uint32_t compute_bankers(unsigned long a); + +const char *about(void) +{ + return "Count genotype intersections across all possible sample subsets in a vcf file.\n"; +} + + +const char *usage(void) +{ + return + "\n" + "About: Count genotype intersections across all possible sample subsets in a vcf file.\n" + "Usage: bcftools +GTisec [General Options] -- [Plugin Options] \n" + "\n" + "Options:\n" + " run \"bcftools plugin\" for a list of common options\n" + "\n" + "Plugin options:\n" + " -m, --missing if set, include count of missing genotypes per sample in output\n" + " -v, --verbose if set, annotate count rows with corresponding sample subset lists\n" + " -H, --human-readable if set, create human readable output; i.e. sort output by sample and\n" + " print each subset's intersection count once for each sample contained\n" + " in the subset; implies verbose output (-v)\n" + "\n" + "Example:\n" + " bcftools +GTisec in.vcf -- -v # for verbose output\n" + " bcftools +GTisec in.vcf -- -H # for human readable output\n" + "\n"; +} + + +int init(int argc, char **argv, bcf_hdr_t *in, bcf_hdr_t *out) +{ + memset(&args,0,sizeof(args_t)); + args.flag = 0; + + static struct option loptions[] = + { + {"help", no_argument, 0,'h'}, + {"missing", no_argument, 0,'m'}, + {"verbose", no_argument, 0,'v'}, + {"human-readable", no_argument, 0,'H'}, + {0,0,0,0} + }; + + int c; + while ((c = getopt_long(argc, argv, "?mvHh",loptions,NULL)) >= 0) + { + switch (c) + { + case 'm': args.flag |= MISSING; break; + case 'v': args.flag |= VERBOSE; break; + case 'H': args.flag |= ( SMPORDER | VERBOSE ); break; + case 'h': usage(); break; + case '?': + default: error("%s", usage()); break; + } + } + if ( optind != argc ) usage(); // too many files given + + + args.hdr = in; + + if ( !bcf_hdr_nsamples(args.hdr) ) + { + error("No samples in input file.\n"); + } + + args.nsmp = bcf_hdr_nsamples(args.hdr); + if ( args.nsmp > 32 ) error("Too many samples. A maximum of 32 is supported.\n"); + args.nsmpp2 = pow( 2, args.nsmp); + args.bankers = (uint32_t*) calloc( args.nsmpp2, sizeof(uint32_t) ); + args.quick = (uint64_t*) calloc((args.nsmp * (args.nsmp + 1)) / 4, sizeof(unsigned long)); + if ( args.flag & MISSING ) args.missing_gts = (uint64_t*) calloc( args.nsmp, sizeof(uint64_t)); + args.smp_is = (uint64_t*) calloc( args.nsmpp2, sizeof(uint64_t)); + if ( bcf_hdr_id2int(args.hdr, BCF_DT_ID, "GT")<0 ) error("[E::%s] GT not present in the header\n", __func__); + + args.gt_arr = NULL; + args.ngt_arr = 0; + + args.out = stdout; + + /*! Header printing */ + FILE *fp = args.out; + fprintf(fp, "# This file was produced by bcftools +GTisec (%s+htslib-%s)\n", bcftools_version(), hts_version()); + fprintf(fp, "# The command line was:\tbcftools +GTisec %s ", argv[0]); + int i; + for (i=1; i < argc; i++) + { + fprintf(fp, " %s", argv[i]); + } + fprintf(fp,"\n"); + fprintf(fp,"# This file can be used as input to the subset plotting tools at:\n" + "# https://github.com/dlaehnemann/bankers2\n"); + fprintf(fp,"# Genotype intersections across samples:\n"); + fprintf(fp,"@SMPS"); + for (i = args.nsmp-1; i >= 0; i--) + { + fprintf(fp," %s", bcf_hdr_int2id(args.hdr, BCF_DT_SAMPLE, i)); + } + fprintf(fp,"\n"); + if ( args.flag & MISSING ) + { + if ( args.flag & SMPORDER ) + { + fprintf(fp, "# The first line of each sample contains its count of missing genotypes, with a '-' appended\n" + "# to the sample name.\n"); + } + else + { + fprintf(fp, "# The first %i lines contain the counts for missing values of each sample in the order provided\n" + "# in the SMPS-line above. Intersection counts only start afterwards.\n", args.nsmp); + } + } + if ( args.flag & SMPORDER ) + { + fprintf(fp, "# Human readable output (-H) was requested. Subset intersection counts are therefore sorted by\n" + "# sample and repeated for each contained sample. For each sample, counts are in banker's \n" + "# sequence order regarding all other samples.\n"); + } + else + { + fprintf(fp, "# Subset intersection counts are in global banker's sequence order.\n"); + if ( args.nsmp > 2 ) + { + fprintf(fp, "# After exclusive sample counts in order of the SMPS-line, banker's sequence continues with:\n" + "# %s,%s %s,%s ...\n", + bcf_hdr_int2id(in, BCF_DT_SAMPLE, args.nsmp-1 ), + bcf_hdr_int2id(in, BCF_DT_SAMPLE, args.nsmp-2 ), + bcf_hdr_int2id(in, BCF_DT_SAMPLE, args.nsmp-1 ), + bcf_hdr_int2id(in, BCF_DT_SAMPLE, args.nsmp-3 ) + ); + } + } + if (args.flag & VERBOSE ) + { + fprintf(fp,"# [1] Number of shared non-ref genotypes \t[2] Samples sharing non-ref genotype (GT)\n"); + } + else + { + fprintf(fp,"# [1] Number of shared non-ref genotypes\n"); + } + + /* Compute banker's sequence for following printing by sample and + * with increasing subset size. + */ + uint32_t j; + for ( j = 0; j < args.nsmpp2; j++ ) + { + args.bankers[j] = compute_bankers(j); + } + + return 1; +} + + +/* ADAPTED CODE FROM CORIN LAWSON (START) + * https://github.com/au-phiware/bankers/blob/master/c/bankers.c + * who implemented ideas of Eric Burnett: + * http://www.thelowlyprogrammer.com/2010/04/indexing-and-enumerating-subsets-of.html + */ + +/* + * Compute the binomial coefficient of `n choose k'. + * Use the fact that binom(n, k) = binom(n, n - k). + * Use a lookup table (triangle, actually) for speed. + * Otherwise it's dumb (heart) recursion. + * Added relative to Corin Lawson: + * * Passing in of sample number through pointer to args struct + * * Make quick lookup table external to keep it persistent with clean allocation + * and freeing + */ +uint64_t choose(unsigned int n, unsigned int k) { + if (n == 0) + return 0; + if (n == k || k == 0) + return 1; + if (k > n / 2) + k = n - k; + + unsigned int i = (n * (n - 1)) / 4 + k - 1; + if (args.quick[i] == 0) + args.quick[i] = choose(n - 1, k - 1) + choose(n - 1, k); + + return args.quick[i]; +} + +/* + * Returns the Banker's number at the specified position, a. + * Derived from the recursive bit flip method. + * Added relative to Corin Lawson: + * * Uses same lookup table solution as choose function, just + * maintained externally to persist across separate function calls. + * * Uses bitwise symmetry of banker's sequence to use bitwise inversion + * instead of recursive bit flip for second half of sequence. + */ +uint32_t compute_bankers(unsigned long a) +{ + if (a == 0) + return 0; + + if ( args.bankers[a] == 0 ) + { + if ( a >= (args.nsmpp2 / 2) ) + return args.bankers[a] = ( compute_bankers(args.nsmpp2 - (a+1)) ^ (args.nsmpp2 - 1) ); // use bitwise symmetry of bankers sequence + unsigned int c = 0; + uint32_t n = args.nsmp; + uint64_t e = a, binom; + binom = choose(n, c); + do { + e -= binom; + } while ((binom = choose(n, ++c)) <= e); + + do { + if (e == 0 || (binom = choose(n - 1, c - 1)) > e) + c--, args.bankers[a] |= 1; + else + e -= binom; + } while (--n && c && ((args.bankers[a] <<= 1) || 1)); + args.bankers[a] <<= n; + } + + return args.bankers[a]; +} + +// ADAPTED CODE FROM CORIN LAWSON END + + +/* + * GT field (genotype) comparison function. + */ +bcf1_t *process(bcf1_t *rec) +{ + uint64_t i; + bcf_unpack(rec, BCF_UN_FMT); // unpack the Format fields, including the GT field + int gte_smp = 0; // number GT array entries per sample (should be 2, one entry per allele) + if ( (gte_smp = bcf_get_genotypes(args.hdr, rec, &(args.gt_arr), &(args.ngt_arr) ) ) <= 0 ) + { + error("GT not present at %s: %d\n", args.hdr->id[BCF_DT_CTG][rec->rid].key, rec->pos+1); + } + + gte_smp /= args.nsmp; // divide total number of genotypes array entries (= args.ngt_arr) by number of samples + int ret; + + // stick all genotypes in a hash as keys and store up to 32 samples in a corresponding flag as its value + khiter_t bucket; + khash_t(gts2smps) *gts = kh_init(gts2smps); // create hash + for ( i = 0; i < args.nsmp; i++ ) + { + int *gt_ptr = args.gt_arr + gte_smp * i; + + if (bcf_gt_is_missing(gt_ptr[0]) || ( gte_smp == 2 && bcf_gt_is_missing(gt_ptr[1]) ) ) + { + if ( args.flag & MISSING ) args.missing_gts[i]++; // count missing genotypes, if requested + continue; // don't do anything else for missing genotypes, their "sharing" gives no info... + } + + int a = bcf_gt_allele(gt_ptr[0]); + int b; + if ( gte_smp == 2 ) // two entries available per sample, padded with missing values for haploid genotypes + { + b = bcf_gt_allele(gt_ptr[1]); + } + else if (gte_smp == 1 ) // use missing value for second entry in hash key generation below, if only one is available + { + b = bcf_gt_allele(bcf_int32_vector_end); + } + else + { + error("gtisec does not support ploidy higher than 2.\n"); + } + + int idx = bcf_alleles2gt(a,b); // generate genotype specific hash key + + bucket = kh_get(gts2smps, gts, idx); // get the genotype's hash bucket + + if ( bucket == kh_end(gts) ) { // means that key does not exist + bucket = kh_put(gts2smps, gts, idx, &ret); // create bucket with genotype index as key and return its iterator + kh_val(gts, bucket) = 0; // initialize the bucket with all sample bits unset + } + kh_value(gts, bucket) |= (1<= 0; s--) + { + if ( args.flag & MISSING ) // if missing genotype counts are requested, print them to standard output + { + fprintf(fp, "%"PRIu64"\t%s-\n", args.missing_gts[s], bcf_hdr_int2id(args.hdr, BCF_DT_SAMPLE, s)); + } + for ( i = 1; i < args.nsmpp2; i++ ) + { + if ( (args.bankers[i]>>s) & 1 ) + { + fprintf(fp, "%"PRIu64"\t", args.smp_is[ args.bankers[i] ]); // print out count of genotypes shared by samples in current banker's sequence position + int j; + /* Print sample list */ + fprintf(fp, "%s", bcf_hdr_int2id(args.hdr, BCF_DT_SAMPLE, s)); // print current sample first + for ( j = args.nsmp-1; j >= 0; j-- ) + { + if ( (args.bankers[i] ^ (1<= 0; s--) + { + fprintf(fp, "%"PRIu64"\t%s-\n", args.missing_gts[s], bcf_hdr_int2id(args.hdr, BCF_DT_SAMPLE, s)); + } + } + for ( i = 1; i < args.nsmpp2; i++ ) + { + fprintf(fp, "%"PRIu64"\t", args.smp_is[ args.bankers[i] ]); // print out count of genotypes shared by samples in current banker's sequence position + int j = 0; + for ( s = args.nsmp-1; s >= 0; s--) + { + if ( (args.bankers[i]>>s) & 1 ) + { + fprintf(fp, "%s%s", j ? "," : "", bcf_hdr_int2id(args.hdr, BCF_DT_SAMPLE, s) ); // samples in specified order + j = 1; + } + } + fprintf(fp, "\n" ); + } + } + else + { + if ( args.flag & MISSING ) // if missing genotype counts are requested, print them to standard output + { + for ( s = args.nsmp-1; s >= 0; s--) + { + fprintf(fp, "%"PRIu64"\n", args.missing_gts[s]); + } + } + for ( i = 1; i < args.nsmpp2; i++ ) + { + fprintf(fp, "%"PRIu64"\n", args.smp_is[ args.bankers[i] ]); // print out count of genotypes shared by samples in current banker's sequence position + } + } + fclose(fp); + + /* freeing up args */ + free(args.gt_arr); + free(args.bankers); + free(args.quick); + if (args.flag & MISSING) free(args.missing_gts); + free(args.smp_is); +} diff --git a/plugins/GTisec.mk b/plugins/GTisec.mk new file mode 100644 index 0000000..58d1cc7 --- /dev/null +++ b/plugins/GTisec.mk @@ -0,0 +1,2 @@ +plugins/GTisec.so: plugins/GTisec.c version.h version.c + $(CC) $(PLUGIN_FLAGS) $(CFLAGS) $(EXTRA_CPPFLAGS) $(CPPFLAGS) $(LDFLAGS) -o $@ version.c $< $(LIBS) diff --git a/plugins/GTsubset.c b/plugins/GTsubset.c new file mode 100644 index 0000000..69e7dbe --- /dev/null +++ b/plugins/GTsubset.c @@ -0,0 +1,266 @@ +/* plugins/GTsubset.c -- output only positions where the selected samples exclusively + share a genotype, i.e. all selected samples must have the same + genotype (including both alleles) and none of the unselected + samples can have the same genotype + + Copyright (C) 2016 Computational Biology of Infection Research, + Helmholtz Centre for Infection Research, Braunschweig, + Germany + + Author: David Laehnemann + +Permission is hereby granted, free of charge, to any person obtaining a copy +of this software and associated documentation files (the "Software"), to deal +in the Software without restriction, including without limitation the rights +to use, copy, modify, merge, publish, distribute, sublicense, and/or sell +copies of the Software, and to permit persons to whom the Software is +furnished to do so, subject to the following conditions: + +The above copyright notice and this permission notice shall be included in +all copies or substantial portions of the Software. + +THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL +THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER +LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING +FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER +DEALINGS IN THE SOFTWARE. */ + +#include +#include +#include +#include +#include +#include + +#include +#include + +#include "bcftools.h" + +typedef struct _args_t +{ + bcf_hdr_t *hdr; /*! VCF file header */ + int *gt_arr; /*! temporary array, to store GTs of current line/record */ + int ngt_arr; /*! hold the number of current GT array entries */ + int nsmp; /*! number of samples, can be determined from header but is needed in multiple contexts */ + int n_sel_smps; /*! number of selected samples who should exclusively share genotypes */ + int *selected_smps; /*! pointer to start of array containing 1 at indices corresponding to selected samples in header dict and 0 at others*/ +} +args_t; + +static args_t args; + +const char *about(void) +{ + return "Output only sites where the requested samples all exclusively share a genotype (GT).\n"; +} + + +const char *usage(void) +{ + return + "\n" + "About: Output only sites where the requested samples all exclusively share a genotype (GT), i.e.\n" + " all selected samples must have the same GT, while non of the others can have it.\n" + "Usage: bcftools +GTsubset [General Options] -- [Plugin Options] \n" + "\n" + "Options:\n" + " run \"bcftools plugin\" for a list of common options\n" + "\n" + "Plugin options:\n" + " -s,--sample-list comma-separated list of samples; only those sites where all of these\n" + " samples exclusively share their genotype are given as output\n" + "\n" + "Example:\n" + " bcftools +GTsubset in.vcf -- -s SMP1,SMP2 \n" + "\n"; +} + + +int init(int argc, char **argv, bcf_hdr_t *in, bcf_hdr_t *out) +{ + memset(&args,0,sizeof(args_t)); + + int i; + + static struct option loptions[] = + { + {"help", no_argument, 0,'h'}, + {"sample-list", required_argument, 0,'s'}, + {0,0,0,0} + }; + + char **smps_strs = NULL; + + int c; + while ((c = getopt_long(argc, argv, "?s:h",loptions,NULL)) >= 0) + { + switch (c) + { + case 's': smps_strs = hts_readlist(optarg,0,&(args.n_sel_smps)); + if ( args.n_sel_smps == 0 ) + { + fprintf(stderr, "Sample specification not valid.\n"); + error("%s", usage()); + } + break; + case 'h': usage(); break; + case '?': + default: error("%s", usage()); break; + } + } + if ( optind != argc ) usage(); // too many files given + + args.hdr = bcf_hdr_dup(in); + + // Samples parsing from header and input option + if ( !bcf_hdr_nsamples(args.hdr) ) + { + error("No samples in input file.\n"); + } + args.nsmp = bcf_hdr_nsamples(args.hdr); + args.selected_smps = (int*) calloc(args.nsmp,sizeof(int)); + for ( i = 0; i < args.n_sel_smps; i++ ) + { + int ind = bcf_hdr_id2int(args.hdr, BCF_DT_SAMPLE, smps_strs[i]); + if ( ind == -1 ) + { + error("Sample '%s' not in input vcf file.\n", smps_strs[i]); + } else { + args.selected_smps[ind] = 1; + } + free(smps_strs[i]); + } + free(smps_strs); + + /* + fprintf(stderr, "Selected samples array:["); + for (i=0;iid[BCF_DT_CTG][rec->rid].key, rec->pos+1); + } + + gte_smp /= args.nsmp; // divide total number of genotypes array entries (= args.ngt_arr) by number of samples + + // initialize with missing genotype + int a1 = 0; + int a2 = 0; + + // initialize with first selected sample genotype that is not missing + int gt = -1; + while ( (a1 == 0) || (a2 == 0) ) + { + gt++; + if (gt == args.nsmp) break; + if (args.selected_smps[gt] == 0) continue; + a1 = (args.gt_arr + gte_smp * gt)[0]; + if ( gte_smp == 2 ) a2 = (args.gt_arr + gte_smp * gt)[1]; + else if ( gte_smp == 1 ) a2 = bcf_int32_vector_end; + else error("GTsubset does not support ploidy higher than 2.\n"); + } +// fprintf(stderr, "a1: %i a2: %i\n", a1, a2); + + // check all genotypes if they match (for included samples) or disagree (for samples not included) + gt = 0; + for ( i = 0; i < args.nsmp; i++ ) + { + int *gt_ptr = args.gt_arr + gte_smp * i; + + int b1 = gt_ptr[0]; + int b2; + if ( gte_smp == 2 ) // two entries available per sample, padded with missing values for haploid genotypes + { + b2 = gt_ptr[1]; + } + else if (gte_smp == 1 ) // use vector end value for second entry, if only one is available + { + b2 = bcf_int32_vector_end; + } + else + { + error("GTsubset does not support ploidy higher than 2.\n"); + } + + // fprintf(stderr, "b1: %i b2: %i\n", b1, b2); + /* missing genotypes are counted as always passing, as they neither + * mismatch the initial selected genotype for a selected sample, nor + * do they match the initial selected genotype for an excluded sample's + * genotype */ + if ( (b1 == 0) || (b2 == 0) ) + { + gt++; +// fprintf(stderr, "missing => pass\n"); + continue; + } + else if ( args.selected_smps[i] == 1 ) + { + if ( (b1 == a1) && (b2 == a2) ) + { + gt++; +// fprintf(stderr, "match => pass\n"); + continue; + } + else + { +// fprintf(stderr, "no match => fail\n"); + break; + } + } + else if ( args.selected_smps[i] == 0 ) + { + if ( (b1 != a1 ) || (b2 != a2) ) + { + gt++; + // fprintf(stderr, "no match => pass\n"); + continue; + } + else + { +// fprintf(stderr, "match => fail\n"); + break; + } + } + } + if ( gt == args.nsmp ) + { + return rec; + } + else + { + return NULL; + } +} + +void destroy(void) +{ + /* freeing up args */ + bcf_hdr_destroy(args.hdr); + free(args.gt_arr); + free(args.selected_smps); +} diff --git a/plugins/GTsubset.mk b/plugins/GTsubset.mk new file mode 100644 index 0000000..9e90936 --- /dev/null +++ b/plugins/GTsubset.mk @@ -0,0 +1,2 @@ +plugins/GTsubset.so: plugins/GTsubset.c version.h version.c + $(CC) $(PLUGIN_FLAGS) $(CFLAGS) $(EXTRA_CPPFLAGS) $(CPPFLAGS) $(LDFLAGS) -o $@ version.c $< $(LIBS) diff --git a/plugins/ad-bias.c b/plugins/ad-bias.c new file mode 100644 index 0000000..ee6a07e --- /dev/null +++ b/plugins/ad-bias.c @@ -0,0 +1,226 @@ +/* The MIT License + + Copyright (c) 2016 Genome Research Ltd. + + Author: Petr Danecek + + Permission is hereby granted, free of charge, to any person obtaining a copy + of this software and associated documentation files (the "Software"), to deal + in the Software without restriction, including without limitation the rights + to use, copy, modify, merge, publish, distribute, sublicense, and/or sell + copies of the Software, and to permit persons to whom the Software is + furnished to do so, subject to the following conditions: + + The above copyright notice and this permission notice shall be included in + all copies or substantial portions of the Software. + + THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR + IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, + FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE + AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER + LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, + OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN + THE SOFTWARE. + + */ + +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include "bcftools.h" +#include "convert.h" + +typedef struct +{ + int smpl,ctrl; // VCF sample index + const char *smpl_name, *ctrl_name; +} +pair_t; + +typedef struct +{ + bcf_hdr_t *hdr; + pair_t *pair; + int npair, mpair, min_dp, min_alt_dp; + int32_t *ad_arr; + int mad_arr; + double th; + convert_t *convert; + kstring_t str; + uint64_t nsite,ncmp; +} +args_t; + +args_t args; + +const char *about(void) +{ + return "Find positions with wildly varying ALT allele frequency (Fisher test on FMT/AD).\n"; +} + +const char *usage(void) +{ + return + "\n" + "About: Find positions with wildly varying ALT allele frequency (Fisher test on FMT/AD).\n" + "Usage: bcftools +ad-bias [General Options] -- [Plugin Options]\n" + "Options:\n" + " run \"bcftools plugin\" for a list of common options\n" + "\n" + "Plugin options:\n" + " -a, --min-alt-dp Minimum required alternate allele depth [1]\n" + " -d, --min-dp Minimum required depth [0]\n" + " -f, --format Optional tags to append to output (`bcftools query` style of format)\n" + " -s, --samples List of sample pairs, one tab-delimited pair per line\n" + " -t, --threshold Output only hits with p-value smaller than [1e-3]\n" + "\n" + "Example:\n" + " bcftools +ad-bias file.bcf -- -t 1e-3 -s samples.txt\n" + "\n"; +} + +void parse_samples(args_t *args, char *fname) +{ + htsFile *fp = hts_open(fname, "r"); + if ( !fp ) error("Could not read: %s\n", fname); + + kstring_t str = {0,0,0}; + if ( hts_getline(fp, KS_SEP_LINE, &str) <= 0 ) error("Empty file: %s\n", fname); + + int moff = 0, *off = NULL; + do + { + // HPSI0513i-veqz_6 HPSI0513pf-veqz + int ncols = ksplit_core(str.s,'\t',&moff,&off); + if ( ncols<2 ) error("Could not parse the sample file: %s\n", str.s); + + int smpl = bcf_hdr_id2int(args->hdr,BCF_DT_SAMPLE,&str.s[off[0]]); + if ( smpl<0 ) continue; + int ctrl = bcf_hdr_id2int(args->hdr,BCF_DT_SAMPLE,&str.s[off[1]]); + if ( ctrl<0 ) continue; + + args->npair++; + hts_expand0(pair_t,args->npair,args->mpair,args->pair); + pair_t *pair = &args->pair[args->npair-1]; + pair->ctrl = ctrl; + pair->smpl = smpl; + pair->smpl_name = bcf_hdr_int2id(args->hdr,BCF_DT_SAMPLE,pair->smpl); + pair->ctrl_name = bcf_hdr_int2id(args->hdr,BCF_DT_SAMPLE,pair->ctrl); + } while ( hts_getline(fp, KS_SEP_LINE, &str)>=0 ); + + free(str.s); + free(off); + hts_close(fp); +} + +int init(int argc, char **argv, bcf_hdr_t *in, bcf_hdr_t *out) +{ + memset(&args,0,sizeof(args_t)); + args.hdr = in; + args.th = 1e-3; + args.min_alt_dp = 1; + char *fname = NULL, *format = NULL; + static struct option loptions[] = + { + {"min-dp",required_argument,NULL,'d'}, + {"min-alt-dp",required_argument,NULL,'a'}, + {"format",required_argument,NULL,'f'}, + {"samples",required_argument,NULL,'s'}, + {"threshold",required_argument,NULL,'t'}, + {NULL,0,NULL,0} + }; + int c; + char *tmp; + while ((c = getopt_long(argc, argv, "?hs:t:f:d:a:",loptions,NULL)) >= 0) + { + switch (c) + { + case 'a': + args.min_alt_dp = strtol(optarg,&tmp,10); + if ( *tmp ) error("Could not parse: -a %s\n", optarg); + break; + case 'd': + args.min_dp = strtol(optarg,&tmp,10); + if ( *tmp ) error("Could not parse: -d %s\n", optarg); + break; + case 't': + args.th = strtod(optarg,&tmp); + if ( *tmp ) error("Could not parse: -t %s\n", optarg); + break; + case 's': fname = optarg; break; + case 'f': format = optarg; break; + case 'h': + case '?': + default: error("%s", usage()); break; + } + } + if ( !fname ) error("Expected the -s option\n"); + parse_samples(&args, fname); + if ( format ) args.convert = convert_init(args.hdr, NULL, 0, format); + printf("# This file was produced by: bcftools +ad-bias(%s+htslib-%s)\n", bcftools_version(),hts_version()); + printf("# The command line was:\tbcftools +ad-bias %s", argv[0]); + for (c=1; csmpl; + int32_t *bptr = args.ad_arr + nad*pair->ctrl; + + if ( aptr[0]==bcf_int32_missing ) continue; + if ( bptr[0]==bcf_int32_missing ) continue; + if ( aptr[0]+aptr[1] < args.min_dp ) continue; + if ( bptr[0]+bptr[1] < args.min_dp ) continue; + if ( aptr[1] < args.min_alt_dp && bptr[1] < args.min_alt_dp ) continue; + + args.ncmp++; + + int n11 = aptr[0], n12 = aptr[1]; + int n21 = bptr[0], n22 = bptr[1]; + double left, right, fisher; + kt_fisher_exact(n11,n12,n21,n22, &left,&right,&fisher); + if ( fisher >= args.th ) continue; + + printf("FT\t%s\t%s\t%s\t%d\t%d\t%d\t%d\t%d\t%e", + pair->smpl_name,pair->ctrl_name, + bcf_hdr_id2name(args.hdr,rec->rid), rec->pos+1, + n11,n12,n21,n22, fisher + ); + if ( args.convert ) printf("\t%s", args.str.s); + printf("\n"); + } + return NULL; +} + +void destroy(void) +{ + printf("# SN, Summary Numbers\t[2]Number of Pairs\t[3]Number of Sites\t[4]Number of comparisons\t[5]P-value output threshold\n"); + printf("SN\t%d\t%"PRId64"\t%"PRId64"\t%e\n",args.npair,args.nsite,args.ncmp,args.th); + if (args.convert) convert_destroy(args.convert); + free(args.str.s); + free(args.pair); + free(args.ad_arr); +} diff --git a/plugins/ad-bias.mk b/plugins/ad-bias.mk new file mode 100644 index 0000000..b6a33a6 --- /dev/null +++ b/plugins/ad-bias.mk @@ -0,0 +1,2 @@ +plugins/ad-bias.so: plugins/ad-bias.c version.h version.c convert.h convert.c + $(CC) $(PLUGIN_FLAGS) $(CFLAGS) $(EXTRA_CPPFLAGS) $(CPPFLAGS) $(LDFLAGS) -o $@ convert.c version.c $< $(LIBS) diff --git a/plugins/af-dist.c b/plugins/af-dist.c new file mode 100644 index 0000000..819adc9 --- /dev/null +++ b/plugins/af-dist.c @@ -0,0 +1,220 @@ +/* The MIT License + + Copyright (c) 2016 Genome Research Ltd. + + Author: Petr Danecek + + Permission is hereby granted, free of charge, to any person obtaining a copy + of this software and associated documentation files (the "Software"), to deal + in the Software without restriction, including without limitation the rights + to use, copy, modify, merge, publish, distribute, sublicense, and/or sell + copies of the Software, and to permit persons to whom the Software is + furnished to do so, subject to the following conditions: + + The above copyright notice and this permission notice shall be included in + all copies or substantial portions of the Software. + + THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR + IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, + FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE + AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER + LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, + OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN + THE SOFTWARE. + + */ + +#include +#include +#include +#include +#include +#include +#include "bcftools.h" +#include "bin.h" + +typedef struct +{ + char *af_tag; + bcf_hdr_t *hdr; + int32_t *gt, ngt, naf; + float *af, list_min, list_max; + bin_t *dev_bins, *prob_bins; + uint64_t *dev_dist, *prob_dist; +} +args_t; + +args_t *args; + +const char *about(void) +{ + return "AF and GT probability distribution stats.\n"; +} + +const char *usage(void) +{ + return + "\n" + "About: Collect AF deviation stats and GT probability distribution\n" + " given AF and assuming HWE\n" + "Usage: bcftools +af-dist [General Options] -- [Plugin Options]\n" + "Options:\n" + " run \"bcftools plugin\" for a list of common options\n" + "\n" + "Plugin options:\n" + " -d, --dev-bins AF deviation bins\n" + " -l, --list list genotypes from the given bin (for debugging)\n" + " -p, --prob-bins probability distribution bins\n" + " -t, --af-tag VCF INFO tag to use [AF]\n" + "\n" + "Default binning:\n" + " -d: 0,0.1,0.2,0.3,0.4,0.5,0.6,0.7,0.8,0.9,1\n" + " -p: 0,0.1,0.2,0.3,0.4,0.5,0.6,0.7,0.8,0.9,1\n" + "Example:\n" + " bcftools +af-tag file.bcf -- -t EUR_AF -p bins.txt\n" + "\n"; +} + +int init(int argc, char **argv, bcf_hdr_t *in, bcf_hdr_t *out) +{ + args = (args_t*) calloc(1,sizeof(args_t)); + char *dev_bins = "0,0.1,0.2,0.3,0.4,0.5,0.6,0.7,0.8,0.9,1"; + char *prob_bins = "0,0.1,0.2,0.3,0.4,0.5,0.6,0.7,0.8,0.9,1"; + args->hdr = in; + args->af_tag = "AF"; + args->list_min = -1; + static struct option loptions[] = + { + {"list",required_argument,NULL,'l'}, + {"dev-bins",required_argument,NULL,'d'}, + {"prob-bins",required_argument,NULL,'p'}, + {"af-tag",required_argument,NULL,'t'}, + {NULL,0,NULL,0} + }; + int c; + while ((c = getopt_long(argc, argv, "?ht:d:p:l:",loptions,NULL)) >= 0) + { + switch (c) + { + case 'l': + { + char *a,*b; + args->list_min = strtod(optarg,&a); + if ( a==optarg || *a!=',' ) error("Could not parse: --list %s\n", optarg); + args->list_max = strtod(a+1,&b); + if ( a+1==b || *b ) error("Could not parse: --list %s\n", optarg); + break; + } + case 'd': dev_bins = optarg; break; + case 'p': prob_bins = optarg; break; + case 't': args->af_tag = optarg; break; + case 'h': + case '?': + default: error("%s", usage()); break; + } + } + + args->dev_bins = bin_init(dev_bins,0,1); + int nbins = bin_get_size(args->dev_bins); + args->dev_dist = (uint64_t*)calloc(nbins,sizeof(*args->dev_dist)); + + args->prob_bins = bin_init(prob_bins,0,1); + nbins = bin_get_size(args->prob_bins); + args->prob_dist = (uint64_t*)calloc(nbins,sizeof(*args->prob_dist)); + + printf("# This file was produced by: bcftools +af-dist(%s+htslib-%s)\n", bcftools_version(),hts_version()); + printf("# The command line was:\tbcftools +af-dist %s", argv[0]); + for (c=1; clist_min!=-1 ) + printf("# GT, genotypes with P(AF) in [%f,%f]; [2]Chromosome\t[3]Position[4]Sample\t[5]Genotype\t[6]AF-based probability\n",args->list_min,args->list_max); + + return 1; +} + +bcf1_t *process(bcf1_t *rec) +{ + int naf = bcf_get_info_float(args->hdr,rec,args->af_tag,&args->af,&args->naf); + if ( naf<=0 ) return NULL; + float af = args->af[0]; + + float pRA = 2*af*(1-af); + float pAA = af*af; + int iRA = bin_get_idx(args->prob_bins,pRA); + int iAA = bin_get_idx(args->prob_bins,pAA); + + int list_RA = args->list_min==-1 || pRA < args->list_min || pRA > args->list_max ? 0 : 1; + int list_AA = args->list_min==-1 || pAA < args->list_min || pAA > args->list_max ? 0 : 1; + const char *chr = bcf_seqname(args->hdr,rec); + + int ngt = bcf_get_genotypes(args->hdr, rec, &args->gt, &args->ngt); + int i, j, nsmpl = bcf_hdr_nsamples(args->hdr); + int nals = 0, nalt = 0; + ngt /= nsmpl; + for (i=0; igt + i*ngt; + int dosage = 0; + for (j=0; jprob_dist[iRA]++; + if ( list_RA ) printf("GT\t%s\t%d\t%s\t1\t%f\n",chr,rec->pos+1,args->hdr->samples[i],pRA); + } + else if ( dosage==2 ) + { + args->prob_dist[iAA]++; + if ( list_AA ) printf("GT\t%s\t%d\t%s\t2\t%f\n",chr,rec->pos+1,args->hdr->samples[i],pAA); + } + } + + if ( nals && (nalt || af) ) + { + float af_dev = fabs(af - (float)nalt/nals); + int iAF = bin_get_idx(args->dev_bins,af_dev); + args->dev_dist[iAF]++; + } + + return NULL; +} + +void destroy(void) +{ + printf("# PROB_DIST, genotype probability distribution, assumes HWE\n"); + int i, n; + n = bin_get_size(args->prob_bins); + for (i=0; iprob_bins,i); + float max = bin_get_value(args->prob_bins,i+1); + printf("PROB_DIST\t%f\t%f\t%"PRId64"\n", min,max,args->prob_dist[i]); + } + printf("# DEV_DIST, distribution of AF deviation, based on %s and INFO/AN, AC calculated on the fly\n", args->af_tag); + n = bin_get_size(args->dev_bins); + for (i=0; idev_bins,i); + float max = bin_get_value(args->dev_bins,i+1); + printf("DEV_DIST\t%f\t%f\t%"PRId64"\n", min,max,args->dev_dist[i]); + } + bin_destroy(args->dev_bins); + bin_destroy(args->prob_bins); + free(args->dev_dist); + free(args->prob_dist); + free(args->gt); + free(args->af); + free(args); +} + + diff --git a/plugins/af-dist.mk b/plugins/af-dist.mk new file mode 100644 index 0000000..2ee23c7 --- /dev/null +++ b/plugins/af-dist.mk @@ -0,0 +1,2 @@ +plugins/af-dist.so: plugins/af-dist.c version.h version.c bin.h bin.c + $(CC) $(PLUGIN_FLAGS) $(CFLAGS) $(EXTRA_CPPFLAGS) $(CPPFLAGS) $(LDFLAGS) -o $@ bin.c version.c $< $(LIBS) diff --git a/plugins/check-sparsity.c b/plugins/check-sparsity.c new file mode 100644 index 0000000..f5ee54b --- /dev/null +++ b/plugins/check-sparsity.c @@ -0,0 +1,273 @@ +/* + Copyright (C) 2017 Genome Research Ltd. + + Author: Petr Danecek + + Permission is hereby granted, free of charge, to any person obtaining a copy + of this software and associated documentation files (the "Software"), to deal + in the Software without restriction, including without limitation the rights + to use, copy, modify, merge, publish, distribute, sublicense, and/or sell + copies of the Software, and to permit persons to whom the Software is + furnished to do so, subject to the following conditions: + + The above copyright notice and this permission notice shall be included in + all copies or substantial portions of the Software. + + THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR + IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, + FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE + AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER + LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, + OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN + THE SOFTWARE. +*/ + +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include "bcftools.h" + +typedef struct +{ + int argc; + char **argv, *fname, *region, **regs; + int region_is_file, nregs, regs_free; + int *smpl, nsmpl, *nsites, min_sites, gt_id; + kstring_t tmps; + bcf1_t *rec; + tbx_t *tbx; + hts_idx_t *idx; + hts_itr_t *itr; + htsFile *fp; + bcf_hdr_t *hdr; +} +args_t; + +const char *about(void) +{ + return "Print samples without genotypes in a region or chromosome\n"; +} + +static const char *usage_text(void) +{ + return + "\n" + "About: Print samples without genotypess in a region (-r/-R) or chromosome (the default)\n" + "\n" + "Usage: bcftools +check-sparsity [Plugin Options]\n" + "Plugin options:\n" + " -n, --n-markers minimum number of required markers [1]\n" + " -r, --regions restrict to comma-separated list of regions\n" + " -R, --regions-file restrict to regions listed in a file\n" + "\n"; +} + +static void init_data(args_t *args) +{ + args->fp = hts_open(args->fname,"r"); + if ( !args->fp ) error("Could not read %s\n", args->fname); + args->hdr = bcf_hdr_read(args->fp); + if ( !args->hdr ) error("Could not read the header: %s\n", args->fname); + + args->rec = bcf_init1(); + args->gt_id = bcf_hdr_id2int(args->hdr,BCF_DT_ID,"GT"); + if ( args->gt_id<0 ) error("Error: GT field is not present\n"); + + int i; + args->nsmpl = bcf_hdr_nsamples(args->hdr); + args->nsites = (int*) calloc(args->nsmpl, sizeof(int)); + args->smpl = (int*) malloc(sizeof(int)*args->nsmpl); + for (i=0; insmpl; i++) args->smpl[i] = i; + + if ( strcmp("-",args->fname) ) // not reading from stdin + { + if ( hts_get_format(args->fp)->format==vcf ) + { + args->tbx = tbx_index_load(args->fname); + if ( !args->tbx && args->region ) error("Could not load the VCF index, please drop the -r/-R option\n"); + } + else if ( hts_get_format(args->fp)->format==bcf ) + { + args->idx = bcf_index_load(args->fname); + if ( !args->idx && args->region ) error("Could not load the BCF index, please drop the -r/-R option\n"); + } + } + else if ( args->region ) error("Cannot use index with this file, please drop the -r/-R option\n"); + + if ( args->tbx || args->idx ) + { + if ( args->region ) + { + args->regs = hts_readlist(args->region, args->region_is_file, &args->nregs); + if ( !args->regs ) error("Could not parse regions: %s\n", args->region); + args->regs_free = 1; + } + else + args->regs = (char**) (args->tbx ? tbx_seqnames(args->tbx, &args->nregs) : bcf_index_seqnames(args->idx, args->hdr, &args->nregs)); + } +} +static void destroy_data(args_t *args) +{ + int i; + if ( args->regs_free ) + for (i=0; inregs; i++) free(args->regs[i]); + free(args->regs); + bcf_hdr_destroy(args->hdr); + bcf_destroy(args->rec); + free(args->tmps.s); + free(args->smpl); + free(args->nsites); + if ( args->itr ) hts_itr_destroy(args->itr); + if ( args->tbx ) tbx_destroy(args->tbx); + if ( args->idx ) hts_idx_destroy(args->idx); + hts_close(args->fp); +} + +static void report(args_t *args, const char *reg) +{ + int i; + for (i=0; insmpl; i++) + printf("%s\t%s\n", reg, args->hdr->samples[args->smpl[i]]); + args->nsmpl = bcf_hdr_nsamples(args->hdr); + for (i=0; insmpl; i++) args->smpl[i] = i; + memset(args->nsites, 0, sizeof(int)*args->nsmpl); +} +static void test_region(args_t *args, char *reg) +{ + if ( args->tbx ) + { + args->itr = tbx_itr_querys(args->tbx,reg); + if ( !args->itr ) return; + } + else if ( args->idx ) + { + args->itr = bcf_itr_querys(args->idx,args->hdr,reg); + if ( !args->itr ) return; + } + + int ret,i, rid = -1, nread = 0; + while (1) + { + if ( args->tbx ) + { + if ( (ret=tbx_itr_next(args->fp, args->tbx, args->itr, &args->tmps)) < 0 ) break; // no more lines + ret = vcf_parse1(&args->tmps, args->hdr, args->rec); + if ( ret<0 ) error("Could not parse the line: %s\n", args->tmps.s); + } + else if ( args->idx ) + { + ret = bcf_itr_next(args->fp, args->itr, args->rec); + if ( ret < -1 ) error("Could not parse a line from %s\n", reg); + if ( ret < 0 ) break; // no more lines or an error + } + else + { + if ( args->fp->format.format==vcf ) + { + if ( (ret=hts_getline(args->fp, KS_SEP_LINE, &args->tmps)) < 0 ) break; // no more lines + ret = vcf_parse1(&args->tmps, args->hdr, args->rec); + if ( ret<0 ) error("Could not parse the line: %s\n", args->tmps.s); + } + else if ( args->fp->format.format==bcf ) + { + ret = bcf_read1(args->fp, args->hdr, args->rec); + if ( ret < -1 ) error("Could not parse %s\n", args->fname); + if ( ret < 0 ) break; // no more lines or an error + } + if ( rid!=-1 && rid!=args->rec->rid ) + { + report(args, bcf_hdr_id2name(args->hdr,rid)); + nread = 0; + } + rid = args->rec->rid; + } + + bcf_unpack(args->rec, BCF_UN_FMT); + bcf_fmt_t *fmt_gt = NULL; + for (i=0; irec->n_fmt; i++) + if ( args->rec->d.fmt[i].id==args->gt_id ) { fmt_gt = &args->rec->d.fmt[i]; break; } + if ( !fmt_gt ) continue; // no GT tag + if ( fmt_gt->n==0 ) continue; // empty?! + if ( fmt_gt->type!=BCF_BT_INT8 ) error("TODO: the GT fmt_type is not int8!\n"); + + // update the array of missing samples + for (i=0; insmpl; i++) + { + int8_t *ptr = (int8_t*) (fmt_gt->p + args->smpl[i]*fmt_gt->size); + int ial = 0; + for (ial=0; ialn; ial++) + if ( ptr[ial]==bcf_gt_missing || ptr[ial]==bcf_int8_vector_end ) break; + if ( ial==0 ) continue; // missing + if ( ++args->nsites[i] < args->min_sites ) continue; + if ( i+1nsmpl ) + { + memmove(args->smpl+i, args->smpl+i+1, sizeof(int)*(args->nsmpl-i-1)); + memmove(args->nsites+i, args->nsites+i+1, sizeof(int)*(args->nsmpl-i-1)); + } + args->nsmpl--; + i--; + } + nread = 1; + if ( !args->nsmpl ) break; + } + if ( nread ) report(args, rid==-1 ? reg : bcf_hdr_id2name(args->hdr,rid)); + + tbx_itr_destroy(args->itr); + args->itr = NULL; +} + +int run(int argc, char **argv) +{ + args_t *args = (args_t*) calloc(1,sizeof(args_t)); + args->argc = argc; args->argv = argv; + args->min_sites = 1; + static struct option loptions[] = + { + {"n-markers",required_argument,NULL,'n'}, + {"regions",required_argument,NULL,'r'}, + {"regions-file",required_argument,NULL,'R'}, + {NULL,0,NULL,0} + }; + int c,i; + char *tmp; + while ((c = getopt_long(argc, argv, "vr:R:n:",loptions,NULL)) >= 0) + { + switch (c) + { + case 'n': + args->min_sites = strtol(optarg,&tmp,10); + if ( *tmp ) error("Could not parse: -n %s\n", optarg); + break; + case 'R': args->region_is_file = 1; + case 'r': args->region = optarg; break; + case 'h': + case '?': + default: error("%s", usage_text()); break; + } + } + + if ( optind>=argc ) + { + if ( !isatty(fileno((FILE *)stdin)) ) args->fname = "-"; // reading from stdin + else error(usage_text()); + } + else args->fname = argv[optind]; + init_data(args); + + for (i=0; inregs; i++) test_region(args, args->regs[i]); + if ( !args->nregs ) test_region(args, NULL); + + destroy_data(args); + free(args); + return 0; +} + diff --git a/plugins/color-chrs.c b/plugins/color-chrs.c new file mode 100644 index 0000000..ea92300 --- /dev/null +++ b/plugins/color-chrs.c @@ -0,0 +1,561 @@ +/* The MIT License + + Copyright (c) 2015 Genome Research Ltd. + + Author: Petr Danecek + + Permission is hereby granted, free of charge, to any person obtaining a copy + of this software and associated documentation files (the "Software"), to deal + in the Software without restriction, including without limitation the rights + to use, copy, modify, merge, publish, distribute, sublicense, and/or sell + copies of the Software, and to permit persons to whom the Software is + furnished to do so, subject to the following conditions: + + The above copyright notice and this permission notice shall be included in + all copies or substantial portions of the Software. + + THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR + IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, + FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE + AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER + LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, + OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN + THE SOFTWARE. + + */ + +/* + Trio haplotypes: mother (A,B), father (C,D), child (E,F) + Modeling the following states: + 01|23|02 + 01|23|03 + 01|23|12 + 01|23|13 + 01|23|20 + 01|23|30 + 01|23|21 + 01|23|31 + with the likelihoods of two haplotypes A,B segments sharing an allele: + P(01|A==B) .. e (P of error) + P(00|A==B) .. 1-e + and + P(ab,cd,ef|E=A,F=C) = P(ea|E=A)*P(fc|F=C) + + + Unrelated samples: (A,B) and (C,D) + Modeling the states: + xxxx .. A!=C,A!=D,B!=C,B!=D + 0x0x .. A=C,B!=D + 0xx0 .. A=D,B!=C + x00x .. B=C,A!=D + x0x0 .. B=D,A!=C + 0101 .. A=C,B=D + 0110 .. A=D,B=C + with the likelihoods + P(01|A!=B) .. f*(1-f) + P(00|A!=B) .. (1-f)*(1-f) + P(11|A!=B) .. f*f + + Assuming 2x30 crossovers, P=2e-8. + */ + +#include +#include +#include +#include +#include +#include +#include +#include "bcftools.h" +#include "HMM.h" + +#define C_TRIO 1 +#define C_UNRL 2 + +// states for unrelated samples +#define UNRL_xxxx 0 +#define UNRL_0x0x 1 +#define UNRL_0xx0 2 +#define UNRL_x00x 3 +#define UNRL_x0x0 4 +#define UNRL_0101 5 +#define UNRL_0110 6 + +// trio states +#define TRIO_AC 0 +#define TRIO_AD 1 +#define TRIO_BC 2 +#define TRIO_BD 3 +#define TRIO_CA 4 +#define TRIO_DA 5 +#define TRIO_CB 6 +#define TRIO_DB 7 + +typedef struct _args_t +{ + bcf_hdr_t *hdr; + hmm_t *hmm; + double *eprob, *tprob, pij, pgt_err; + uint32_t *sites; + int32_t *gt_arr; + int nsites, msites, ngt_arr, prev_rid; + int mode, nstates, nhet_father, nhet_mother; + int imother,ifather,ichild, isample,jsample; + void (*set_observed_prob) (bcf1_t *rec); + char *prefix; + FILE *fp; +} +args_t; + +static args_t args; + +#define SW_MOTHER 1 +#define SW_FATHER 2 +static int hap_switch[8][8]; + +static void set_observed_prob_trio(bcf1_t *rec); +static void set_observed_prob_unrelated(bcf1_t *rec); +static void init_hmm_trio(args_t *args); +static void init_hmm_unrelated(args_t *args); + + +const char *about(void) +{ + return "Color shared chromosomal segments, requires phased GTs.\n"; +} + +const char *usage(void) +{ + return + "\n" + "About: Color shared chromosomal segments, requires phased GTs. The output\n" + " can be visualized using the color-chrs.pl script.\n" + "Usage: bcftools +color-chrs [General Options] -- [Plugin Options]\n" + "Options:\n" + " run \"bcftools plugin\" for a list of common options\n" + "\n" + "Plugin options:\n" + " -p, --prefix output files prefix\n" + " -t, --trio names of mother, father and the child\n" + " -u, --unrelated names of two unrelated samples\n" + "\n" + "Example:\n" + " bcftools +color-chrs in.vcf --\n" + "\n"; +} + +int init(int argc, char **argv, bcf_hdr_t *in, bcf_hdr_t *out) +{ + char *trio_samples = NULL, *unrelated_samples = NULL; + memset(&args,0,sizeof(args_t)); + args.prev_rid = -1; + args.hdr = in; + args.pij = 2e-8; + args.pgt_err = 1e-9; + + static struct option loptions[] = + { + {"prefix",1,0,'p'}, + {"trio",1,0,'t'}, + {"unrelated",1,0,'u'}, + {0,0,0,0} + }; + int c; + while ((c = getopt_long(argc, argv, "?ht:u:p:",loptions,NULL)) >= 0) + { + switch (c) + { + case 'p': args.prefix = optarg; break; + case 't': trio_samples = optarg; break; + case 'u': unrelated_samples = optarg; break; + case 'h': + case '?': + default: error("%s", usage()); break; + } + } + if ( optind != argc ) error(usage()); + if ( trio_samples && unrelated_samples ) error("Expected only one of the -t/-u options\n"); + if ( !trio_samples && !unrelated_samples ) error("Expected one of the -t/-u options\n"); + if ( !args.prefix ) error("Expected the -p option\n"); + + int ret = bcf_hdr_set_samples(args.hdr, trio_samples ? trio_samples : unrelated_samples, 0); + if ( ret<0 ) error("Could not parse samples: %s\n", trio_samples ? trio_samples : unrelated_samples); + else if ( ret>0 ) error("%d-th sample not found: %s\n", ret,trio_samples ? trio_samples : unrelated_samples); + + if ( trio_samples ) + { + int i,n = 0; + char **list = hts_readlist(trio_samples, 0, &n); + if ( n!=3 ) error("Expected three sample names with -t\n"); + args.imother = bcf_hdr_id2int(args.hdr, BCF_DT_SAMPLE, list[0]); + args.ifather = bcf_hdr_id2int(args.hdr, BCF_DT_SAMPLE, list[1]); + args.ichild = bcf_hdr_id2int(args.hdr, BCF_DT_SAMPLE, list[2]); + for (i=0; instates = 8; + args->tprob = (double*) malloc(sizeof(double)*args->nstates*args->nstates); + + for (i=0; instates; i++) + for (j=0; jnstates; j++) hap_switch[i][j] = 0; + + hap_switch[TRIO_AD][TRIO_AC] = SW_FATHER; + hap_switch[TRIO_BC][TRIO_AC] = SW_MOTHER; + hap_switch[TRIO_BD][TRIO_AC] = SW_MOTHER | SW_FATHER; + hap_switch[TRIO_AC][TRIO_AD] = SW_FATHER; + hap_switch[TRIO_BC][TRIO_AD] = SW_MOTHER | SW_FATHER; + hap_switch[TRIO_BD][TRIO_AD] = SW_MOTHER; + hap_switch[TRIO_AC][TRIO_BC] = SW_MOTHER; + hap_switch[TRIO_AD][TRIO_BC] = SW_MOTHER | SW_FATHER; + hap_switch[TRIO_BD][TRIO_BC] = SW_FATHER; + hap_switch[TRIO_AC][TRIO_BD] = SW_MOTHER | SW_FATHER; + hap_switch[TRIO_AD][TRIO_BD] = SW_MOTHER; + hap_switch[TRIO_BC][TRIO_BD] = SW_FATHER; + + hap_switch[TRIO_DA][TRIO_CA] = SW_FATHER; + hap_switch[TRIO_CB][TRIO_CA] = SW_MOTHER; + hap_switch[TRIO_DB][TRIO_CA] = SW_MOTHER | SW_FATHER; + hap_switch[TRIO_CA][TRIO_DA] = SW_FATHER; + hap_switch[TRIO_CB][TRIO_DA] = SW_MOTHER | SW_FATHER; + hap_switch[TRIO_DB][TRIO_DA] = SW_MOTHER; + hap_switch[TRIO_CA][TRIO_CB] = SW_MOTHER; + hap_switch[TRIO_DA][TRIO_CB] = SW_MOTHER | SW_FATHER; + hap_switch[TRIO_DB][TRIO_CB] = SW_FATHER; + hap_switch[TRIO_CA][TRIO_DB] = SW_MOTHER | SW_FATHER; + hap_switch[TRIO_DA][TRIO_DB] = SW_MOTHER; + hap_switch[TRIO_CB][TRIO_DB] = SW_FATHER; + + for (i=0; instates; i++) + { + for (j=0; jnstates; j++) + { + if ( !hap_switch[i][j] ) MAT(args->tprob,args->nstates,i,j) = 0; + else + { + MAT(args->tprob,args->nstates,i,j) = 1; + if ( hap_switch[i][j] & SW_MOTHER ) MAT(args->tprob,args->nstates,i,j) *= args->pij; + if ( hap_switch[i][j] & SW_FATHER ) MAT(args->tprob,args->nstates,i,j) *= args->pij; + } + } + } + for (i=0; instates; i++) + { + double sum = 0; + for (j=0; jnstates; j++) + { + if ( i!=j ) sum += MAT(args->tprob,args->nstates,i,j); + } + MAT(args->tprob,args->nstates,i,i) = 1 - sum; + } + + #if 0 + for (i=0; instates; i++) + { + for (j=0; jnstates; j++) + fprintf(stderr,"\t%d",hap_switch[j][i]); + fprintf(stderr,"\n"); + } + for (i=0; instates; i++) + { + for (j=0; jnstates; j++) + fprintf(stderr,"\t%e",MAT(args->tprob,args->nstates,j,i)); + fprintf(stderr,"\n"); + } + #endif + + args->hmm = hmm_init(args->nstates, args->tprob, 10000); +} +static void init_hmm_unrelated(args_t *args) +{ + int i,j; + args->nstates = 7; + args->tprob = (double*) malloc(sizeof(double)*args->nstates*args->nstates); + + for (i=0; instates; i++) + { + for (j=0; jnstates; j++) + MAT(args->tprob,args->nstates,i,j) = args->pij; + } + MAT(args->tprob,args->nstates,UNRL_0101,UNRL_xxxx) = args->pij*args->pij; + MAT(args->tprob,args->nstates,UNRL_0110,UNRL_xxxx) = args->pij*args->pij; + MAT(args->tprob,args->nstates,UNRL_x0x0,UNRL_0x0x) = args->pij*args->pij; + MAT(args->tprob,args->nstates,UNRL_0110,UNRL_0x0x) = args->pij*args->pij; + MAT(args->tprob,args->nstates,UNRL_x00x,UNRL_0xx0) = args->pij*args->pij; + MAT(args->tprob,args->nstates,UNRL_0101,UNRL_0xx0) = args->pij*args->pij; + MAT(args->tprob,args->nstates,UNRL_0101,UNRL_x00x) = args->pij*args->pij; + MAT(args->tprob,args->nstates,UNRL_0110,UNRL_x0x0) = args->pij*args->pij; + MAT(args->tprob,args->nstates,UNRL_0110,UNRL_0101) = args->pij*args->pij; + + for (i=0; instates; i++) + { + for (j=i+1; jnstates; j++) + MAT(args->tprob,args->nstates,i,j) = MAT(args->tprob,args->nstates,j,i); + } + for (i=0; instates; i++) + { + double sum = 0; + for (j=0; jnstates; j++) + if ( i!=j ) sum += MAT(args->tprob,args->nstates,i,j); + MAT(args->tprob,args->nstates,i,i) = 1 - sum; + } + + #if 0 + for (i=0; instates; i++) + { + for (j=0; jnstates; j++) + fprintf(stderr,"\t%e",MAT(args->tprob,args->nstates,j,i)); + fprintf(stderr,"\n"); + } + #endif + + args->hmm = hmm_init(args->nstates, args->tprob, 10000); +} +static inline double prob_shared(float af, int a, int b) +{ + return a==b ? 1-args.pgt_err : args.pgt_err; +} +static inline double prob_not_shared(float af, int a, int b) +{ + if ( a!=b ) return af*(1-af); + else if ( a==0 ) return (1-af)*(1-af); + else return af*af; +} +static void set_observed_prob_unrelated(bcf1_t *rec) +{ + float af = 0.5; // alternate allele frequency + + int ngt = bcf_get_genotypes(args.hdr, rec, &args.gt_arr, &args.ngt_arr); + if ( ngt<0 ) return; + if ( ngt!=4 ) return; // chrX + + int32_t a,b,c,d; + a = args.gt_arr[2*args.isample]; + b = args.gt_arr[2*args.isample+1]; + c = args.gt_arr[2*args.jsample]; + d = args.gt_arr[2*args.jsample+1]; + if ( bcf_gt_is_missing(a) || bcf_gt_is_missing(b) ) return; + if ( bcf_gt_is_missing(c) || bcf_gt_is_missing(d) ) return; + if ( !bcf_gt_is_phased(a) && !bcf_gt_is_phased(b) ) return; // only the second allele should be set when phased + if ( !bcf_gt_is_phased(c) && !bcf_gt_is_phased(d) ) return; + a = bcf_gt_allele(a); + b = bcf_gt_allele(b); + c = bcf_gt_allele(c); + d = bcf_gt_allele(d); + + int m = args.msites; + args.nsites++; + hts_expand(uint32_t,args.nsites,args.msites,args.sites); + if ( m!=args.msites ) args.eprob = (double*) realloc(args.eprob, sizeof(double)*args.msites*args.nstates); + + args.sites[args.nsites-1] = rec->pos; + double *prob = args.eprob + args.nstates*(args.nsites-1); + prob[UNRL_xxxx] = prob_not_shared(af,a,c) * prob_not_shared(af,a,d) * prob_not_shared(af,b,c) * prob_not_shared(af,b,d); + prob[UNRL_0x0x] = prob_shared(af,a,c) * prob_not_shared(af,b,d); + prob[UNRL_0xx0] = prob_shared(af,a,d) * prob_not_shared(af,b,c); + prob[UNRL_x00x] = prob_shared(af,b,c) * prob_not_shared(af,a,d); + prob[UNRL_x0x0] = prob_shared(af,b,d) * prob_not_shared(af,a,c); + prob[UNRL_0101] = prob_shared(af,a,c) * prob_shared(af,b,d); + prob[UNRL_0110] = prob_shared(af,a,d) * prob_shared(af,b,c); + +#if 0 + static int x = 0; + if ( !x++) + { + printf("p(0==0) .. %f\n", prob_shared(af,0,0)); + printf("p(0!=0) .. %f\n", prob_not_shared(af,0,0)); + printf("p(0==1) .. %f\n", prob_shared(af,0,1)); + printf("p(0!=1) .. %f\n", prob_not_shared(af,0,1)); + } + printf("%d|%d %d|%d x:%f 11:%f 12:%f 21:%f 22:%f 11,22:%f 12,21:%f %d\n", a,b,c,d, + prob[UNRL_xxxx], prob[UNRL_0x0x], prob[UNRL_0xx0], prob[UNRL_x00x], prob[UNRL_x0x0], prob[UNRL_0101], prob[UNRL_0110], rec->pos+1); +#endif +} +static void set_observed_prob_trio(bcf1_t *rec) +{ + int ngt = bcf_get_genotypes(args.hdr, rec, &args.gt_arr, &args.ngt_arr); + if ( ngt<0 ) return; + if ( ngt!=6 ) return; // chrX + + int32_t a,b,c,d,e,f; + a = args.gt_arr[2*args.imother]; + b = args.gt_arr[2*args.imother+1]; + c = args.gt_arr[2*args.ifather]; + d = args.gt_arr[2*args.ifather+1]; + e = args.gt_arr[2*args.ichild]; + f = args.gt_arr[2*args.ichild+1]; + if ( bcf_gt_is_missing(a) || bcf_gt_is_missing(b) ) return; + if ( bcf_gt_is_missing(c) || bcf_gt_is_missing(d) ) return; + if ( bcf_gt_is_missing(e) || bcf_gt_is_missing(f) ) return; + if ( !bcf_gt_is_phased(a) && !bcf_gt_is_phased(b) ) return; // only the second allele should be set when phased + if ( !bcf_gt_is_phased(c) && !bcf_gt_is_phased(d) ) return; + if ( !bcf_gt_is_phased(e) && !bcf_gt_is_phased(f) ) return; + a = bcf_gt_allele(a); + b = bcf_gt_allele(b); + c = bcf_gt_allele(c); + d = bcf_gt_allele(d); + e = bcf_gt_allele(e); + f = bcf_gt_allele(f); + + int mother = (1<pos; + double *prob = args.eprob + args.nstates*(args.nsites-1); + prob[TRIO_AC] = prob_shared(0,e,a) * prob_shared(0,f,c); + prob[TRIO_AD] = prob_shared(0,e,a) * prob_shared(0,f,d); + prob[TRIO_BC] = prob_shared(0,e,b) * prob_shared(0,f,c); + prob[TRIO_BD] = prob_shared(0,e,b) * prob_shared(0,f,d); + prob[TRIO_CA] = prob_shared(0,e,c) * prob_shared(0,f,a); + prob[TRIO_DA] = prob_shared(0,e,d) * prob_shared(0,f,a); + prob[TRIO_CB] = prob_shared(0,e,c) * prob_shared(0,f,b); + prob[TRIO_DB] = prob_shared(0,e,d) * prob_shared(0,f,b); +} + +void flush_viterbi(args_t *args) +{ + const char *s1, *s2, *s3 = NULL; + if ( args->mode==C_UNRL ) + { + s1 = bcf_hdr_int2id(args->hdr,BCF_DT_SAMPLE,args->isample); + s2 = bcf_hdr_int2id(args->hdr,BCF_DT_SAMPLE,args->jsample); + } + else if ( args->mode==C_TRIO ) + { + s1 = bcf_hdr_int2id(args->hdr,BCF_DT_SAMPLE,args->imother); + s3 = bcf_hdr_int2id(args->hdr,BCF_DT_SAMPLE,args->ifather); + s2 = bcf_hdr_int2id(args->hdr,BCF_DT_SAMPLE,args->ichild); + } + else abort(); + + if ( !args->fp ) + { + kstring_t str = {0,0,0}; + kputs(args->prefix, &str); + kputs(".dat", &str); + args->fp = fopen(str.s,"w"); + if ( !args->fp ) error("%s: %s\n", str.s,strerror(errno)); + free(str.s); + fprintf(args->fp,"# SG, shared segment\t[2]Chromosome\t[3]Start\t[4]End\t[5]%s:1\t[6]%s:2\n",s2,s2); + fprintf(args->fp,"# SW, number of switches\t[3]Sample\t[4]Chromosome\t[5]nHets\t[5]nSwitches\t[6]switch rate\n"); + } + + hmm_run_viterbi(args->hmm,args->nsites,args->eprob,args->sites); + uint8_t *vpath = hmm_get_viterbi_path(args->hmm); + int i, iprev = -1, prev_state = -1, nstates = hmm_get_nstates(args->hmm); + int nswitch_mother = 0, nswitch_father = 0; + for (i=0; insites; i++) + { + int state = vpath[i*nstates]; + if ( state!=prev_state || i+1==args->nsites ) + { + uint32_t start = iprev>=0 ? args->sites[iprev]+1 : 1, end = i>0 ? args->sites[i-1] : 1; + const char *chr = bcf_hdr_id2name(args->hdr,args->prev_rid); + if ( args->mode==C_UNRL ) + { + switch (prev_state) + { + case UNRL_0x0x: + fprintf(args->fp,"SG\t%s\t%d\t%d\t%s:1\t-\n", chr,start,end,s1); break; + case UNRL_0xx0: + fprintf(args->fp,"SG\t%s\t%d\t%d\t-\t%s:1\n", chr,start,end,s1); break; + case UNRL_x00x: + fprintf(args->fp,"SG\t%s\t%d\t%d\t%s:2\t-\n", chr,start,end,s1); break; + case UNRL_x0x0: + fprintf(args->fp,"SG\t%s\t%d\t%d\t-\t%s:2\n", chr,start,end,s1); break; + case UNRL_0101: + fprintf(args->fp,"SG\t%s\t%d\t%d\t%s:1\t%s:2\n", chr,start,end,s1,s1); break; + case UNRL_0110: + fprintf(args->fp,"SG\t%s\t%d\t%d\t%s:2\t%s:1\n", chr,start,end,s1,s1); break; + } + } + else if ( args->mode==C_TRIO ) + { + switch (prev_state) + { + case TRIO_AC: + fprintf(args->fp,"SG\t%s\t%d\t%d\t%s:1\t%s:1\n", chr,start,end,s1,s3); break; + case TRIO_AD: + fprintf(args->fp,"SG\t%s\t%d\t%d\t%s:1\t%s:2\n", chr,start,end,s1,s3); break; + case TRIO_BC: + fprintf(args->fp,"SG\t%s\t%d\t%d\t%s:2\t%s:1\n", chr,start,end,s1,s3); break; + case TRIO_BD: + fprintf(args->fp,"SG\t%s\t%d\t%d\t%s:2\t%s:2\n", chr,start,end,s1,s3); break; + case TRIO_CA: + fprintf(args->fp,"SG\t%s\t%d\t%d\t%s:1\t%s:1\n", chr,start,end,s3,s1); break; + case TRIO_DA: + fprintf(args->fp,"SG\t%s\t%d\t%d\t%s:2\t%s:1\n", chr,start,end,s3,s1); break; + case TRIO_CB: + fprintf(args->fp,"SG\t%s\t%d\t%d\t%s:1\t%s:2\n", chr,start,end,s3,s1); break; + case TRIO_DB: + fprintf(args->fp,"SG\t%s\t%d\t%d\t%s:2\t%s:2\n", chr,start,end,s3,s1); break; + } + if ( hap_switch[state][prev_state] & SW_MOTHER ) nswitch_mother++; + if ( hap_switch[state][prev_state] & SW_FATHER ) nswitch_father++; + } + iprev = i-1; + } + prev_state = state; + } + float mrate = args->nhet_mother>1 ? (float)nswitch_mother/(args->nhet_mother-1) : 0; + float frate = args->nhet_father>1 ? (float)nswitch_father/(args->nhet_father-1) : 0; + fprintf(args->fp,"SW\t%s\t%s\t%d\t%d\t%f\n", s1,bcf_hdr_id2name(args->hdr,args->prev_rid),args->nhet_mother,nswitch_mother,mrate); + fprintf(args->fp,"SW\t%s\t%s\t%d\t%d\t%f\n", s3,bcf_hdr_id2name(args->hdr,args->prev_rid),args->nhet_father,nswitch_father,frate); + args->nsites = 0; + args->nhet_father = args->nhet_mother = 0; +} + +bcf1_t *process(bcf1_t *rec) +{ + if ( args.prev_rid==-1 ) args.prev_rid = rec->rid; + if ( args.prev_rid!=rec->rid ) flush_viterbi(&args); + args.prev_rid = rec->rid; + args.set_observed_prob(rec); + return NULL; +} + +void destroy(void) +{ + flush_viterbi(&args); + fclose(args.fp); + + free(args.gt_arr); + free(args.tprob); + free(args.sites); + free(args.eprob); + hmm_destroy(args.hmm); +} + + + diff --git a/plugins/color-chrs.mk b/plugins/color-chrs.mk new file mode 100644 index 0000000..506b99d --- /dev/null +++ b/plugins/color-chrs.mk @@ -0,0 +1,2 @@ +plugins/color-chrs.so: plugins/color-chrs.c version.h version.c HMM.h HMM.c + $(CC) $(PLUGIN_FLAGS) $(CFLAGS) $(EXTRA_CPPFLAGS) $(CPPFLAGS) $(LDFLAGS) -o $@ HMM.c version.c $< $(LIBS) diff --git a/plugins/counts.c b/plugins/counts.c new file mode 100644 index 0000000..2d57ba4 --- /dev/null +++ b/plugins/counts.c @@ -0,0 +1,82 @@ +/* plugins/counts.c -- counts SNPs, Indels, and total number of sites. + + Copyright (C) 2013, 2014 Genome Research Ltd. + + Author: Petr Danecek + +Permission is hereby granted, free of charge, to any person obtaining a copy +of this software and associated documentation files (the "Software"), to deal +in the Software without restriction, including without limitation the rights +to use, copy, modify, merge, publish, distribute, sublicense, and/or sell +copies of the Software, and to permit persons to whom the Software is +furnished to do so, subject to the following conditions: + +The above copyright notice and this permission notice shall be included in +all copies or substantial portions of the Software. + +THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL +THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER +LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING +FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER +DEALINGS IN THE SOFTWARE. */ + +#include +#include +#include + +int nsamples, nsnps, nindels, nmnps, nothers, nsites; + +/* + This short description is used to generate the output of `bcftools plugin -l`. +*/ +const char *about(void) +{ + return + "A minimal plugin which counts number of samples, SNPs,\n" + "INDELs, MNPs and total number of sites.\n"; +} + +/* + Called once at startup, allows to initialize local variables. + Return 1 to suppress VCF/BCF header from printing, 0 otherwise. +*/ +int init(int argc, char **argv, bcf_hdr_t *in, bcf_hdr_t *out) +{ + nsamples = bcf_hdr_nsamples(in); + nsnps = nindels = nmnps = nothers = nsites = 0; + return 1; +} + + +/* + Called for each VCF record. Return rec to output the line or NULL + to suppress output. +*/ +bcf1_t *process(bcf1_t *rec) +{ + int type = bcf_get_variant_types(rec); + if ( type & VCF_SNP ) nsnps++; + if ( type & VCF_INDEL ) nindels++; + if ( type & VCF_MNP ) nmnps++; + if ( type & VCF_OTHER ) nothers++; + nsites++; + return NULL; +} + + +/* + Clean up. +*/ +void destroy(void) +{ + printf("Number of samples: %d\n", nsamples); + printf("Number of SNPs: %d\n", nsnps); + printf("Number of INDELs: %d\n", nindels); + printf("Number of MNPs: %d\n", nmnps); + printf("Number of others: %d\n", nothers); + printf("Number of sites: %d\n", nsites); +} + + diff --git a/plugins/dosage.c b/plugins/dosage.c new file mode 100644 index 0000000..ddc6297 --- /dev/null +++ b/plugins/dosage.c @@ -0,0 +1,283 @@ +/* plugins/dosage.c -- prints genotype dosage. + + Copyright (C) 2014 Genome Research Ltd. + + Author: Petr Danecek + +Permission is hereby granted, free of charge, to any person obtaining a copy +of this software and associated documentation files (the "Software"), to deal +in the Software without restriction, including without limitation the rights +to use, copy, modify, merge, publish, distribute, sublicense, and/or sell +copies of the Software, and to permit persons to whom the Software is +furnished to do so, subject to the following conditions: + +The above copyright notice and this permission notice shall be included in +all copies or substantial portions of the Software. + +THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL +THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER +LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING +FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER +DEALINGS IN THE SOFTWARE. */ + +#include +#include +#include +#include +#include + + +/* + This short description is used to generate the output of `bcftools plugin -l`. +*/ +const char *about(void) +{ + return "Prints genotype dosage determined from tags requested by the user.\n"; +} + +const char *usage(void) +{ + return + "\n" + "About: Print genotype dosage\n" + "Usage: bcftools +dosage [General Options] -- [Plugin Options]\n" + "Options:\n" + " run \"bcftools plugin\" for a list of common options\n" + "\n" + "Plugin options:\n" + " -t, --tags VCF tags to determine the dosage from [PL,GL,GT]\n" + "\n" + "Example:\n" + " bcftools +dosage in.vcf -- -t GT\n" + "\n"; +} + +bcf_hdr_t *in_hdr = NULL; +int pl_type = 0, gl_type = 0; +uint8_t *buf = NULL; +int nbuf = 0; // NB: number of elements, not bytes +char **tags = NULL; +int ntags = 0; + +typedef int (*dosage_f) (bcf1_t *); +dosage_f *handlers = NULL; +int nhandlers = 0; + + +int calc_dosage_PL(bcf1_t *rec) +{ + int i, j, nret = bcf_get_format_values(in_hdr,rec,"PL",(void**)&buf,&nbuf,pl_type); + if ( nret<0 ) return -1; + + nret /= rec->n_sample; + #define BRANCH(type_t,is_missing,is_vector_end) \ + { \ + type_t *ptr = (type_t*) buf; \ + for (i=0; in_sample; i++) \ + { \ + float vals[3] = {0,0,0}; \ + for (j=0; jn_sample; + #define BRANCH(type_t,is_missing,is_vector_end) \ + { \ + type_t *ptr = (type_t*) buf; \ + for (i=0; in_sample; i++) \ + { \ + float vals[3] = {0,0,0}; \ + for (j=0; jn_sample; + int32_t *ptr = (int32_t*) buf; + for (i=0; in_sample; i++) + { + float dsg = 0; + for (j=0; j0 ? dsg : -1); + ptr += nret; + } + return 0; +} + + +char **split_list(char *str, int *nitems) +{ + int n = 0, done = 0; + char *ss = strdup(str), **out = NULL; + while ( !done && *ss ) + { + char *se = ss; + while ( *se && *se!=',' ) se++; + if ( !*se ) done = 1; + *se = 0; + n++; + out = (char**) realloc(out,sizeof(char*)*n); + out[n-1] = ss; + ss = se+1; + } + *nitems = n; + return out; +} + +int init(int argc, char **argv, bcf_hdr_t *in, bcf_hdr_t *out) +{ + int i, id, c; + char *tags_str = "PL,GL,GT"; + + static struct option loptions[] = + { + {"tags",1,0,'t'}, + {0,0,0,0} + }; + while ((c = getopt_long(argc, argv, "t:?h",loptions,NULL)) >= 0) + { + switch (c) + { + case 't': tags_str = optarg; break; + case 'h': + case '?': + default: fprintf(stderr,"%s", usage()); exit(1); break; + } + } + tags = split_list(tags_str, &ntags); + + in_hdr = in; + for (i=0; isamples[i]); + printf("\n"); + + return 1; +} + + +bcf1_t *process(bcf1_t *rec) +{ + int i, ret; + + printf("%s\t%d\t%s\t%s", bcf_seqname(in_hdr,rec),rec->pos+1,rec->d.allele[0],rec->n_allele>1 ? rec->d.allele[1] : "."); + if ( rec->n_allele==1 ) + { + for (i=0; in_sample; i++) printf("\t0.0"); + } + else + { + for (i=0; in_sample; i++) printf("\t-1.0"); + } + } + printf("\n"); + + return NULL; +} + + +void destroy(void) +{ + free(handlers); + free(buf); +} + + diff --git a/plugins/fill-AN-AC.c b/plugins/fill-AN-AC.c new file mode 100644 index 0000000..7d6c6f4 --- /dev/null +++ b/plugins/fill-AN-AC.c @@ -0,0 +1,67 @@ +/* plugins/fill-AN-AC.c -- fills AN and AC INFO fields. + + Copyright (C) 2014 Genome Research Ltd. + + Author: Petr Danecek + +Permission is hereby granted, free of charge, to any person obtaining a copy +of this software and associated documentation files (the "Software"), to deal +in the Software without restriction, including without limitation the rights +to use, copy, modify, merge, publish, distribute, sublicense, and/or sell +copies of the Software, and to permit persons to whom the Software is +furnished to do so, subject to the following conditions: + +The above copyright notice and this permission notice shall be included in +all copies or substantial portions of the Software. + +THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL +THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER +LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING +FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER +DEALINGS IN THE SOFTWARE. */ + +#include +#include +#include +#include +#include + +bcf_hdr_t *in_hdr, *out_hdr; +int *arr = NULL, marr = 0; + +const char *about(void) +{ + return "Fill INFO fields AN and AC.\n"; +} + +int init(int argc, char **argv, bcf_hdr_t *in, bcf_hdr_t *out) +{ + in_hdr = in; + out_hdr = out; + bcf_hdr_append(out_hdr, "##INFO="); + bcf_hdr_append(out_hdr, "##INFO="); + return 0; +} + +bcf1_t *process(bcf1_t *rec) +{ + hts_expand(int,rec->n_allele,marr,arr); + int ret = bcf_calc_ac(in_hdr,rec,arr,BCF_UN_FMT); + if ( ret>0 ) + { + int i, an = 0; + for (i=0; in_allele; i++) an += arr[i]; + bcf_update_info_int32(out_hdr, rec, "AN", &an, 1); + bcf_update_info_int32(out_hdr, rec, "AC", arr+1, rec->n_allele-1); + } + return rec; +} + +void destroy(void) +{ + free(arr); +} + + diff --git a/plugins/fill-from-fasta.c b/plugins/fill-from-fasta.c new file mode 100644 index 0000000..80e7a8d --- /dev/null +++ b/plugins/fill-from-fasta.c @@ -0,0 +1,206 @@ +/* plugin/fill-from-fasta.c -- fill-from-fasta plugin. + + Copyright (C) 2016 Genome Research Ltd. + + Author: Shane McCarthy + +Permission is hereby granted, free of charge, to any person obtaining a copy +of this software and associated documentation files (the "Software"), to deal +in the Software without restriction, including without limitation the rights +to use, copy, modify, merge, publish, distribute, sublicense, and/or sell +copies of the Software, and to permit persons to whom the Software is +furnished to do so, subject to the following conditions: + +The above copyright notice and this permission notice shall be included in +all copies or substantial portions of the Software. + +THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL +THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER +LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING +FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER +DEALINGS IN THE SOFTWARE. */ + +#include +#include +#include +#include +#include +#include +#include +#include "filter.h" +#include "bcftools.h" + +const char *about(void) +{ + return "Fill INFO or REF field based on values in a fasta file\n"; +} + +const char *usage(void) +{ + return +"\n" +"About: Fill INFO or REF field based on values in a fasta file.\n" +" The fasta file must be indexed with samtools faidx.\n" +"Usage: bcftools +fill-from-fasta [General Options] -- [Plugin Options]\n" +"\n" +"General options:\n" +" run \"bcftools plugin\" for a list of common options\n" +"\n" +"Plugin options:\n" +" -c, --column REF or INFO tag, e.g. AA for ancestral allele\n" +" -f, --fasta fasta file\n" +" -h, --header-lines optional file containing header lines to append\n" +" -i, --include annotate only records passing filter expression\n" +" -e, --exclude annotate only records failing filter expression\n" + +"\n" +"Examples:\n" +" # fill ancestral allele as INFO/AA for SNP records\n" +" echo '##INFO=' > aa.hdr\n" +" bcftools +fill-from-fasta in.vcf -- -c AA -f aa.fasta -h aa.hdr -i 'TYPE=\"snp\"'\n" +"\n" +" # fix the REF allele in VCFs where REF=N or other\n" +" bcftools +fill-from-fasta in.vcf -- -c REF -f reference.fasta\n" +"\n" +" # select sites marked as P (PASS) in the 1000G Phase3 mask\n" +" echo '##INFO=' > mask.hdr\n" +" bcftools +fill-from-fasta in.vcf -Ou -- -c P3_MASK -f 1000G_mask.fasta -h mask.hdr | bcftools view -i 'P3_MASK=\"P\"'\n" +"\n"; +} + +bcf_hdr_t *in_hdr = NULL, *out_hdr = NULL; +faidx_t *faidx; +int anno = 0; +char *column = NULL; + +#define ANNO_REF 1 +#define ANNO_STRING 2 +#define ANNO_INT 3 + +filter_t *filter; +char *filter_str; +int filter_logic; // one of FLT_INCLUDE/FLT_EXCLUDE (-i or -e) + +#define FLT_INCLUDE 1 +#define FLT_EXCLUDE 2 + +int init(int argc, char **argv, bcf_hdr_t *in, bcf_hdr_t *out) +{ + int c; + char *ref_fname = NULL, *header_fname = NULL; + static struct option loptions[] = + { + {"exclude",required_argument,NULL,'e'}, + {"include",required_argument,NULL,'i'}, + {"column",required_argument,NULL,'c'}, + {"fasta",required_argument,NULL,'f'}, + {"header-lines",required_argument,NULL,'h'}, + {NULL,0,NULL,0} + }; + while ((c = getopt_long(argc, argv, "c:f:?h:i:e:",loptions,NULL)) >= 0) + { + switch (c) + { + case 'e': filter_str = optarg; filter_logic |= FLT_EXCLUDE; break; + case 'i': filter_str = optarg; filter_logic |= FLT_INCLUDE; break; + case 'c': column = optarg; break; + case 'f': ref_fname = optarg; break; + case 'h': header_fname = optarg; break; + case '?': + default: fprintf(stderr,"%s", usage()); exit(1); break; + } + } + in_hdr = in; + out_hdr = out; + if ( filter_logic == (FLT_EXCLUDE|FLT_INCLUDE) ) { fprintf(stderr,"Only one of -i or -e can be given.\n"); return -1; } + + if ( !column ) + { + fprintf(stderr,"--column option is required.\n"); + return -1; + } + if (header_fname) + { + htsFile *file = hts_open(header_fname, "rb"); + if ( !file ) { fprintf(stderr,"Error reading %s\n", header_fname); return -1; } + kstring_t str = {0,0,0}; + while ( hts_getline(file, KS_SEP_LINE, &str) > 0 ) + { + if ( bcf_hdr_append(out_hdr, str.s) ) { fprintf(stderr,"Could not parse %s: %s\n", header_fname, str.s); return -1; } + } + hts_close(file); + free(str.s); + bcf_hdr_sync(out_hdr); + } + if (!strcasecmp("REF", column)) anno = ANNO_REF; + else { + if ( !strncasecmp(column,"INFO/",5) ) column += 5; + int hdr_id = bcf_hdr_id2int(out_hdr, BCF_DT_ID, column); + if (hdr_id<0) { fprintf(stderr,"No header ID found for %s. Header lines can be added with the --header-lines option\n", column); return -1; } + switch ( bcf_hdr_id2type(out_hdr,BCF_HL_INFO,hdr_id) ) + { + case BCF_HT_INT: + anno=ANNO_INT; + break; + case BCF_HT_STR: + anno=ANNO_STRING; + break; + default: + fprintf(stderr,"The type of %s not recognised (%d)\n", column, bcf_hdr_id2type(out_hdr,BCF_HL_INFO,hdr_id)); + return -1; + } + } + if ( !ref_fname ) + { + fprintf(stderr,"No fasta given.\n"); + return -1; + } + faidx = fai_load(ref_fname); + if ( filter_str ) + filter = filter_init(in, filter_str); + return 0; +} + +bcf1_t *process(bcf1_t *rec) +{ + // filter determines if we will annotate the record + // return record unchanged if filter applied + if ( filter ) + { + int ret = filter_test(filter, rec, NULL); + if ( filter_logic==FLT_INCLUDE ) { if ( !ret ) return rec; } + else if ( ret ) return rec; + } + + int i; + char *ref = rec->d.allele[0]; + int ref_len = strlen(ref); + int fa_len; + // could be sped up here by fetching the whole chromosome? could assume + // sorted, but revert to this when non-sorted records found? + char *fa = faidx_fetch_seq(faidx, bcf_seqname(in_hdr,rec), rec->pos, rec->pos+ref_len-1, &fa_len); + if ( !fa ) error("faidx_fetch_seq failed at %s:%d\n", bcf_hdr_id2name(in_hdr,rec->rid), rec->pos+1); + for (i=0; i96 ) fa[i] -= 32; + + assert(ref_len == fa_len); + if (anno==ANNO_REF) + strncpy(rec->d.allele[0], fa, fa_len); + else if (anno==ANNO_STRING) + bcf_update_info_string(out_hdr, rec, column, fa); + else if (anno==ANNO_INT && ref_len==1) + { + int val = atoi(&fa[0]); + bcf_update_info_int32(out_hdr, rec, column, &val, 1); + } + free(fa); + return rec; +} + +void destroy(void) +{ + fai_destroy(faidx); + if (filter) filter_destroy(filter); +} diff --git a/plugins/fill-from-fasta.mk b/plugins/fill-from-fasta.mk new file mode 100644 index 0000000..196578f --- /dev/null +++ b/plugins/fill-from-fasta.mk @@ -0,0 +1,2 @@ +plugins/fill-from-fasta.so: plugins/fill-from-fasta.c version.h version.c filter.h filter.c + $(CC) $(PLUGIN_FLAGS) $(CFLAGS) $(EXTRA_CPPFLAGS) $(CPPFLAGS) $(LDFLAGS) -o $@ filter.c version.c $< $(LIBS) diff --git a/plugins/fill-tags.c b/plugins/fill-tags.c new file mode 100644 index 0000000..7daf049 --- /dev/null +++ b/plugins/fill-tags.c @@ -0,0 +1,621 @@ +/* The MIT License + + Copyright (c) 2015 Genome Research Ltd. + + Author: Petr Danecek + + Permission is hereby granted, free of charge, to any person obtaining a copy + of this software and associated documentation files (the "Software"), to deal + in the Software without restriction, including without limitation the rights + to use, copy, modify, merge, publish, distribute, sublicense, and/or sell + copies of the Software, and to permit persons to whom the Software is + furnished to do so, subject to the following conditions: + + The above copyright notice and this permission notice shall be included in + all copies or substantial portions of the Software. + + THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR + IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, + FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE + AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER + LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, + OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN + THE SOFTWARE. + + */ + +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include "bcftools.h" + +#define SET_AN (1<<0) +#define SET_AC (1<<1) +#define SET_AC_Hom (1<<2) +#define SET_AC_Het (1<<3) +#define SET_AC_Hemi (1<<4) +#define SET_AF (1<<5) +#define SET_NS (1<<6) +#define SET_MAF (1<<7) +#define SET_HWE (1<<8) + +typedef struct +{ + int nhom, nhet, nhemi, nac; +} +counts_t; + +typedef struct +{ + int ns; + int ncounts, mcounts; + counts_t *counts; + char *name, *suffix; + int nsmpl, *smpl; +} +pop_t; + +typedef struct +{ + bcf_hdr_t *in_hdr, *out_hdr; + int npop, tags, drop_missing, gt_id; + pop_t *pop, **smpl2pop; + float *farr; + int32_t *iarr, niarr, miarr, nfarr, mfarr; + double *hwe_probs; + int mhwe_probs; + kstring_t str; +} +args_t; + +static args_t *args; + +const char *about(void) +{ + return "Set INFO tags AF, AC, AC_Hemi, AC_Hom, AC_Het, AN, HWE, MAF, NS.\n"; +} + +const char *usage(void) +{ + return + "\n" + "About: Set INFO tags AF, AC, AC_Hemi, AC_Hom, AC_Het, AN, HWE, MAF, NS.\n" + "Usage: bcftools +fill-tags [General Options] -- [Plugin Options]\n" + "Options:\n" + " run \"bcftools plugin\" for a list of common options\n" + "\n" + "Plugin options:\n" + " -d, --drop-missing do not count half-missing genotypes \"./1\" as hemizygous\n" + " -t, --tags LIST list of output tags. By default, all tags are filled.\n" + " -S, --samples-file FILE list of samples (first column) and comma-separated list of populations (second column)\n" + "\n" + "Example:\n" + " bcftools +fill-tags in.bcf -Ob -o out.bcf\n" + " bcftools +fill-tags in.bcf -Ob -o out.bcf -- -t AN,AC\n" + " bcftools +fill-tags in.bcf -Ob -o out.bcf -- -d\n" + " bcftools +fill-tags in.bcf -Ob -o out.bcf -- -S sample-group.txt -t HWE\n" + "\n"; +} + +void parse_samples(args_t *args, char *fname) +{ + htsFile *fp = hts_open(fname, "r"); + if ( !fp ) error("Could not read: %s\n", fname); + + void *pop2i = khash_str2int_init(); + void *smpli = khash_str2int_init(); + kstring_t str = {0,0,0}; + + int moff = 0, *off = NULL, nsmpl = 0; + while ( hts_getline(fp, KS_SEP_LINE, &str)>=0 ) + { + // NA12400 GRP1 + // NA18507 GRP1,GRP2 + char *pop_names = str.s + str.l - 1; + while ( pop_names >= str.s && isspace(*pop_names) ) pop_names--; + if ( pop_names <= str.s ) error("Could not parse the file: %s\n", str.s); + pop_names[1] = 0; // trailing spaces + while ( pop_names >= str.s && !isspace(*pop_names) ) pop_names--; + if ( pop_names <= str.s ) error("Could not parse the file: %s\n", str.s); + + char *smpl = pop_names++; + while ( smpl >= str.s && isspace(*smpl) ) smpl--; + if ( smpl <= str.s+1 ) error("Could not parse the file: %s\n", str.s); + smpl[1] = 0; + smpl = str.s; + + int ismpl = bcf_hdr_id2int(args->in_hdr,BCF_DT_SAMPLE,smpl); + if ( ismpl<0 ) + { + fprintf(stderr,"Warning: The sample not present in the VCF: %s\n",smpl); + continue; + } + if ( khash_str2int_has_key(smpli,smpl) ) + { + fprintf(stderr,"Warning: The sample is listed twice in %s: %s\n",fname,smpl); + continue; + } + khash_str2int_inc(smpli,strdup(smpl)); + + int i,npops = ksplit_core(pop_names,',',&moff,&off); + for (i=0; inpop); + args->npop++; + args->pop = (pop_t*) realloc(args->pop,args->npop*sizeof(*args->pop)); + memset(args->pop+args->npop-1,0,sizeof(*args->pop)); + args->pop[args->npop-1].name = pop_name; + args->pop[args->npop-1].suffix = (char*)malloc(strlen(pop_name)+2); + memcpy(args->pop[args->npop-1].suffix+1,pop_name,strlen(pop_name)+1); + args->pop[args->npop-1].suffix[0] = '_'; + } + int ipop = 0; + khash_str2int_get(pop2i,pop_name,&ipop); + pop_t *pop = &args->pop[ipop]; + pop->nsmpl++; + pop->smpl = (int*) realloc(pop->smpl,pop->nsmpl*sizeof(*pop->smpl)); + pop->smpl[pop->nsmpl-1] = ismpl; + } + nsmpl++; + } + + if ( nsmpl != bcf_hdr_nsamples(args->in_hdr) ) + fprintf(stderr,"Warning: %d samples in the list, %d samples in the VCF.\n", nsmpl,bcf_hdr_nsamples(args->in_hdr)); + + if ( !args->npop ) error("No populations given?\n"); + + khash_str2int_destroy(pop2i); + khash_str2int_destroy_free(smpli); + free(str.s); + free(off); + hts_close(fp); +} + +void init_pops(args_t *args) +{ + int i,j, nsmpl; + + // add the population "ALL", which is a summary population for all samples + args->npop++; + args->pop = (pop_t*) realloc(args->pop,args->npop*sizeof(*args->pop)); + memset(args->pop+args->npop-1,0,sizeof(*args->pop)); + args->pop[args->npop-1].name = strdup(""); + args->pop[args->npop-1].suffix = strdup(""); + + nsmpl = bcf_hdr_nsamples(args->in_hdr); + args->smpl2pop = (pop_t**) calloc(nsmpl*(args->npop+1),sizeof(pop_t*)); + for (i=0; ismpl2pop[i*(args->npop+1)] = &args->pop[args->npop-1]; + + for (i=0; inpop; i++) + { + for (j=0; jpop[i].nsmpl; j++) + { + int ismpl = args->pop[i].smpl[j]; + pop_t **smpl2pop = &args->smpl2pop[ismpl*(args->npop+1)]; + while (*smpl2pop) smpl2pop++; + *smpl2pop = &args->pop[i]; + } + } +} + +int parse_tags(args_t *args, const char *str) +{ + int i, flag = 0, n_tags; + char **tags = hts_readlist(str, 0, &n_tags); + for(i=0; inpop; i++) + bcf_hdr_printf(args->out_hdr, fmt, args->pop[i].suffix,*args->pop[i].name ? " in " : "",args->pop[i].name); +} + +int init(int argc, char **argv, bcf_hdr_t *in, bcf_hdr_t *out) +{ + args = (args_t*) calloc(1,sizeof(args_t)); + args->in_hdr = in; + args->out_hdr = out; + char *samples_fname = NULL; + static struct option loptions[] = + { + {"drop-missing",0,0,'d'}, + {"tags",1,0,'t'}, + {"samples-file",1,0,'S'}, + {0,0,0,0} + }; + int c; + while ((c = getopt_long(argc, argv, "?ht:dS:",loptions,NULL)) >= 0) + { + switch (c) + { + case 'd': args->drop_missing = 1; break; + case 't': args->tags |= parse_tags(args,optarg); break; + case 'S': samples_fname = optarg; break; + case 'h': + case '?': + default: error("%s", usage()); break; + } + } + + if ( optind != argc ) error(usage()); + + args->gt_id = bcf_hdr_id2int(args->in_hdr,BCF_DT_ID,"GT"); + if ( args->gt_id<0 ) error("Error: GT field is not present\n"); + + if ( !args->tags ) + for (c=0; c<=8; c++) args->tags |= 1<tags & SET_AN ) hdr_append(args, "##INFO="); + if ( args->tags & SET_AC ) hdr_append(args, "##INFO="); + if ( args->tags & SET_NS ) hdr_append(args, "##INFO="); + if ( args->tags & SET_AC_Hom ) hdr_append(args, "##INFO="); + if ( args->tags & SET_AC_Het ) hdr_append(args, "##INFO="); + if ( args->tags & SET_AC_Hemi ) hdr_append(args, "##INFO="); + if ( args->tags & SET_AF ) hdr_append(args, "##INFO="); + if ( args->tags & SET_MAF ) hdr_append(args, "##INFO="); + if ( args->tags & SET_HWE ) hdr_append(args, "##INFO="); + + return 0; +} + +/* + Wigginton 2005, PMID: 15789306 + + nref .. number of reference alleles + nalt .. number of alt alleles + nhet .. number of het genotypes, assuming number of genotypes = (nref+nalt)*2 + +*/ +float calc_hwe(args_t *args, int nref, int nalt, int nhet) +{ + int ngt = (nref+nalt) / 2; + int nrare = nref < nalt ? nref : nalt; + + // sanity check: there is odd/even number of rare alleles iff there is odd/even number of hets + if ( (nrare & 1) ^ (nhet & 1) ) error("nrare/nhet should be both odd or even: nrare=%d nref=%d nalt=%d nhet=%d\n",nrare,nref,nalt,nhet); + if ( nrare < nhet ) error("Fewer rare alleles than hets? nrare=%d nref=%d nalt=%d nhet=%d\n",nrare,nref,nalt,nhet); + if ( (nref+nalt) & 1 ) error("Expected diploid genotypes: nref=%d nalt=%d\n",nref,nalt); + + // initialize het probs + hts_expand(double,nrare+1,args->mhwe_probs,args->hwe_probs); + memset(args->hwe_probs, 0, sizeof(*args->hwe_probs)*(nrare+1)); + double *probs = args->hwe_probs; + + // start at midpoint + int mid = nrare * (nref + nalt - nrare) / (nref + nalt); + + // check to ensure that midpoint and rare alleles have same parity + if ( (nrare & 1) ^ (mid & 1) ) mid++; + + int het = mid; + int hom_r = (nrare - mid) / 2; + int hom_c = ngt - het - hom_r; + double sum = probs[mid] = 1.0; + + for (het = mid; het > 1; het -= 2) + { + probs[het - 2] = probs[het] * het * (het - 1.0) / (4.0 * (hom_r + 1.0) * (hom_c + 1.0)); + sum += probs[het - 2]; + + // 2 fewer heterozygotes for next iteration -> add one rare, one common homozygote + hom_r++; + hom_c++; + } + + het = mid; + hom_r = (nrare - mid) / 2; + hom_c = ngt - het - hom_r; + for (het = mid; het <= nrare - 2; het += 2) + { + probs[het + 2] = probs[het] * 4.0 * hom_r * hom_c / ((het + 2.0) * (het + 1.0)); + sum += probs[het + 2]; + + // add 2 heterozygotes for next iteration -> subtract one rare, one common homozygote + hom_r--; + hom_c--; + } + + for (het=0; het probs[nhet]) continue; + p_rank += probs[het]; + } + + return p_rank > 1 ? 1.0 : p_rank; +} + +static inline void set_counts(pop_t *pop, int is_half, int is_hom, int is_hemi, int als) +{ + int ial; + for (ial=0; als; ial++) + { + if ( als&1 ) + { + if ( is_half ) pop->counts[ial].nac++; + else if ( !is_hom ) pop->counts[ial].nhet++; + else if ( !is_hemi ) pop->counts[ial].nhom += 2; + else pop->counts[ial].nhemi++; + } + als >>= 1; + } + pop->ns++; +} +static void clean_counts(pop_t *pop, int nals) +{ + pop->ns = 0; + memset(pop->counts,0,sizeof(counts_t)*nals); +} + +bcf1_t *process(bcf1_t *rec) +{ + int i,j, nsmpl = bcf_hdr_nsamples(args->in_hdr);; + + bcf_unpack(rec, BCF_UN_FMT); + bcf_fmt_t *fmt_gt = NULL; + for (i=0; in_fmt; i++) + if ( rec->d.fmt[i].id==args->gt_id ) { fmt_gt = &rec->d.fmt[i]; break; } + if ( !fmt_gt ) return rec; // no GT tag + + hts_expand(int32_t,rec->n_allele, args->miarr, args->iarr); + hts_expand(float,rec->n_allele, args->mfarr, args->farr); + for (i=0; inpop; i++) + hts_expand(counts_t,rec->n_allele,args->pop[i].mcounts, args->pop[i].counts); + + for (i=0; inpop; i++) + clean_counts(&args->pop[i], rec->n_allele); + + assert( rec->n_allele < 8*sizeof(int) ); + + #define BRANCH_INT(type_t,vector_end) \ + { \ + for (i=0; ip + i*fmt_gt->size); \ + int ial, als = 0, nals = 0, is_half, is_hom, is_hemi; \ + for (ial=0; ialn; ial++) \ + { \ + if ( p[ial]==vector_end ) break; /* smaller ploidy */ \ + if ( bcf_gt_is_missing(p[ial]) ) continue; /* missing allele */ \ + int idx = bcf_gt_allele(p[ial]); \ + nals++; \ + \ + if ( idx >= rec->n_allele ) \ + error("Incorrect allele (\"%d\") in %s at %s:%d\n",idx,args->in_hdr->samples[i],bcf_seqname(args->in_hdr,rec),rec->pos+1); \ + als |= (1<drop_missing ) is_hemi = 0, is_half = 1; \ + else is_hemi = 1, is_half = 0; \ + } \ + else if ( nals==1 ) is_hemi = 1, is_half = 0; \ + else is_hemi = 0, is_half = 0; \ + pop_t **pop = &args->smpl2pop[i*(args->npop+1)]; \ + while ( *pop ) { set_counts(*pop,is_half,is_hom,is_hemi,als); pop++; }\ + } \ + } + switch (fmt_gt->type) { + case BCF_BT_INT8: BRANCH_INT(int8_t, bcf_int8_vector_end); break; + case BCF_BT_INT16: BRANCH_INT(int16_t, bcf_int16_vector_end); break; + case BCF_BT_INT32: BRANCH_INT(int32_t, bcf_int32_vector_end); break; + default: error("The GT type is not recognised: %d at %s:%d\n",fmt_gt->type, bcf_seqname(args->in_hdr,rec),rec->pos+1); break; + } + #undef BRANCH_INT + + if ( args->tags & SET_NS ) + { + for (i=0; inpop; i++) + { + args->str.l = 0; + ksprintf(&args->str, "NS%s", args->pop[i].suffix); + if ( bcf_update_info_int32(args->out_hdr,rec,args->str.s,&args->pop[i].ns,1)!=0 ) + error("Error occurred while updating %s at %s:%d\n", args->str.s,bcf_seqname(args->in_hdr,rec),rec->pos+1); + } + } + if ( args->tags & SET_AN ) + { + for (i=0; inpop; i++) + { + pop_t *pop = &args->pop[i]; + int32_t an = 0; + for (j=0; jn_allele; j++) + an += pop->counts[j].nhet + pop->counts[j].nhom + pop->counts[j].nhemi + pop->counts[j].nac; + + args->str.l = 0; + ksprintf(&args->str, "AN%s", args->pop[i].suffix); + if ( bcf_update_info_int32(args->out_hdr,rec,args->str.s,&an,1)!=0 ) + error("Error occurred while updating %s at %s:%d\n", args->str.s,bcf_seqname(args->in_hdr,rec),rec->pos+1); + } + } + if ( args->tags & (SET_AF | SET_MAF) ) + { + for (i=0; inpop; i++) + { + int32_t an = 0; + if ( rec->n_allele > 1 ) + { + pop_t *pop = &args->pop[i]; + memset(args->farr, 0, sizeof(*args->farr)*(rec->n_allele-1)); + for (j=1; jn_allele; j++) + args->farr[j-1] += pop->counts[j].nhet + pop->counts[j].nhom + pop->counts[j].nhemi + pop->counts[j].nac; + an = pop->counts[0].nhet + pop->counts[0].nhom + pop->counts[0].nhemi + pop->counts[0].nac; + for (j=1; jn_allele; j++) an += args->farr[j-1]; + if ( !an ) continue; + for (j=1; jn_allele; j++) args->farr[j-1] /= an; + } + if ( args->tags & SET_AF ) + { + args->str.l = 0; + ksprintf(&args->str, "AF%s", args->pop[i].suffix); + if ( bcf_update_info_float(args->out_hdr,rec,args->str.s,args->farr,rec->n_allele-1)!=0 ) + error("Error occurred while updating %s at %s:%d\n", args->str.s,bcf_seqname(args->in_hdr,rec),rec->pos+1); + } + if ( args->tags & SET_MAF ) + { + if ( !an ) continue; + for (j=1; jn_allele; j++) + if ( args->farr[j-1] > 0.5 ) args->farr[j-1] = 1 - args->farr[j-1]; // todo: this is incorrect for multiallelic sites + args->str.l = 0; + ksprintf(&args->str, "MAF%s", args->pop[i].suffix); + if ( bcf_update_info_float(args->out_hdr,rec,args->str.s,args->farr,rec->n_allele-1)!=0 ) + error("Error occurred while updating %s at %s:%d\n", args->str.s,bcf_seqname(args->in_hdr,rec),rec->pos+1); + } + } + } + if ( args->tags & SET_AC ) + { + for (i=0; inpop; i++) + { + if ( rec->n_allele > 1 ) + { + pop_t *pop = &args->pop[i]; + memset(args->iarr, 0, sizeof(*args->iarr)*(rec->n_allele-1)); + for (j=1; jn_allele; j++) + args->iarr[j-1] += pop->counts[j].nhet + pop->counts[j].nhom + pop->counts[j].nhemi + pop->counts[j].nac; + } + args->str.l = 0; + ksprintf(&args->str, "AC%s", args->pop[i].suffix); + if ( bcf_update_info_int32(args->out_hdr,rec,args->str.s,args->iarr,rec->n_allele-1)!=0 ) + error("Error occurred while updating %s at %s:%d\n", args->str.s,bcf_seqname(args->in_hdr,rec),rec->pos+1); + } + } + if ( args->tags & SET_AC_Het ) + { + for (i=0; inpop; i++) + { + if ( rec->n_allele > 1 ) + { + pop_t *pop = &args->pop[i]; + memset(args->iarr, 0, sizeof(*args->iarr)*(rec->n_allele-1)); + for (j=1; jn_allele; j++) + args->iarr[j-1] += pop->counts[j].nhet; + } + args->str.l = 0; + ksprintf(&args->str, "AC_Het%s", args->pop[i].suffix); + if ( bcf_update_info_int32(args->out_hdr,rec,args->str.s,args->iarr,rec->n_allele-1)!=0 ) + error("Error occurred while updating %s at %s:%d\n", args->str.s,bcf_seqname(args->in_hdr,rec),rec->pos+1); + } + } + if ( args->tags & SET_AC_Hom ) + { + for (i=0; inpop; i++) + { + if ( rec->n_allele > 1 ) + { + pop_t *pop = &args->pop[i]; + memset(args->iarr, 0, sizeof(*args->iarr)*(rec->n_allele-1)); + for (j=1; jn_allele; j++) + args->iarr[j-1] += pop->counts[j].nhom; + } + args->str.l = 0; + ksprintf(&args->str, "AC_Hom%s", args->pop[i].suffix); + if ( bcf_update_info_int32(args->out_hdr,rec,args->str.s,args->iarr,rec->n_allele-1)!=0 ) + error("Error occurred while updating %s at %s:%d\n", args->str.s,bcf_seqname(args->in_hdr,rec),rec->pos+1); + } + } + if ( args->tags & SET_AC_Hemi && rec->n_allele > 1 ) + { + for (i=0; inpop; i++) + { + if ( rec->n_allele > 1 ) + { + pop_t *pop = &args->pop[i]; + memset(args->iarr, 0, sizeof(*args->iarr)*(rec->n_allele-1)); + for (j=1; jn_allele; j++) + args->iarr[j-1] += pop->counts[j].nhemi; + } + args->str.l = 0; + ksprintf(&args->str, "AC_Hemi%s", args->pop[i].suffix); + if ( bcf_update_info_int32(args->out_hdr,rec,args->str.s,args->iarr,rec->n_allele-1)!=0 ) + error("Error occurred while updating %s at %s:%d\n", args->str.s,bcf_seqname(args->in_hdr,rec),rec->pos+1); + } + } + if ( args->tags & SET_HWE ) + { + for (i=0; inpop; i++) + { + if ( rec->n_allele > 1 ) + { + pop_t *pop = &args->pop[i]; + memset(args->farr, 0, sizeof(*args->farr)*(rec->n_allele-1)); + int nref_tot = pop->counts[0].nhom; + for (j=0; jn_allele; j++) nref_tot += pop->counts[j].nhet; // NB this neglects multiallelic genotypes + for (j=1; jn_allele; j++) + { + int nref = nref_tot - pop->counts[j].nhet; + int nalt = pop->counts[j].nhet + pop->counts[j].nhom; + int nhet = pop->counts[j].nhet; + args->farr[j-1] = (nref>0 && nalt>0) ? calc_hwe(args, nref, nalt, nhet) : 1; + } + } + args->str.l = 0; + ksprintf(&args->str, "HWE%s", args->pop[i].suffix); + if ( bcf_update_info_float(args->out_hdr,rec,args->str.s,args->farr,rec->n_allele-1)!=0 ) + error("Error occurred while updating %s at %s:%d\n", args->str.s,bcf_seqname(args->in_hdr,rec),rec->pos+1); + } + } + + return rec; +} + +void destroy(void) +{ + int i; + for (i=0; inpop; i++) + { + free(args->pop[i].name); + free(args->pop[i].suffix); + free(args->pop[i].smpl); + free(args->pop[i].counts); + } + free(args->str.s); + free(args->pop); + free(args->smpl2pop); + free(args->iarr); + free(args->farr); + free(args->hwe_probs); + free(args); +} + + + diff --git a/plugins/fixploidy.c b/plugins/fixploidy.c new file mode 100644 index 0000000..04cc076 --- /dev/null +++ b/plugins/fixploidy.c @@ -0,0 +1,230 @@ +/* + Copyright (C) 2014 Genome Research Ltd. + + Author: Petr Danecek + + Permission is hereby granted, free of charge, to any person obtaining a copy + of this software and associated documentation files (the "Software"), to deal + in the Software without restriction, including without limitation the rights + to use, copy, modify, merge, publish, distribute, sublicense, and/or sell + copies of the Software, and to permit persons to whom the Software is + furnished to do so, subject to the following conditions: + + The above copyright notice and this permission notice shall be included in + all copies or substantial portions of the Software. + + THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR + IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, + FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE + AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER + LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, + OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN + THE SOFTWARE. +*/ + +#include +#include +#include +#include +#include +#include +#include +#include +#include "bcftools.h" +#include "ploidy.h" + +static bcf_hdr_t *in_hdr = NULL, *out_hdr = NULL; +static int *sample2sex = NULL; +static int n_sample = 0, nsex = 0, *sex2ploidy = NULL; +static int32_t ngt_arr = 0, *gt_arr = NULL, *gt_arr2 = NULL, ngt_arr2 = 0; +static ploidy_t *ploidy = NULL; + +const char *about(void) +{ + return "Fix ploidy.\n"; +} + +const char *usage(void) +{ + return + "\n" + "About: Fix ploidy\n" + "Usage: bcftools +fixploidy [General Options] -- [Plugin Options]\n" + "Options:\n" + " run \"bcftools plugin\" for a list of common options\n" + "\n" + "Plugin options:\n" + " -p, --ploidy space/tab-delimited list of CHROM,FROM,TO,SEX,PLOIDY\n" + " -s, --sex list of samples, \"NAME SEX\"\n" + " -t, --tags VCF tags to fix [GT]\n" + "\n" + "Example:\n" + " # Default ploidy, if -p not given. Unlisted regions have ploidy 2\n" + " X 1 60000 M 1\n" + " X 2699521 154931043 M 1\n" + " Y 1 59373566 M 1\n" + " Y 1 59373566 F 0\n" + " MT 1 16569 M 1\n" + " MT 1 16569 F 1\n" + " \n" + " # Example of -s file, sex of unlisted samples is \"F\"\n" + " sampleName1 M\n" + " \n" + " bcftools +fixploidy in.vcf -- -s samples.txt\n" + "\n"; +} + +void set_samples(char *fname, bcf_hdr_t *hdr, ploidy_t *ploidy, int *sample2sex) +{ + kstring_t tmp = {0,0,0}; + + htsFile *fp = hts_open(fname, "r"); + if ( !fp ) error("Could not read: %s\n", fname); + while ( hts_getline(fp, KS_SEP_LINE, &tmp) > 0 ) + { + char *ss = tmp.s; + while ( *ss && isspace(*ss) ) ss++; + if ( !*ss ) error("Could not parse: %s\n", tmp.s); + if ( *ss=='#' ) continue; + char *se = ss; + while ( *se && !isspace(*se) ) se++; + char x = *se; *se = 0; + + int ismpl = bcf_hdr_id2int(hdr, BCF_DT_SAMPLE, ss); + if ( ismpl < 0 ) { fprintf(stderr,"Warning: No such sample in the VCF: %s\n",ss); continue; } + + *se = x; + ss = se+1; + while ( *ss && isspace(*ss) ) ss++; + if ( !*ss ) error("Could not parse: %s\n", tmp.s); + se = ss; + while ( *se && !isspace(*se) ) se++; + if ( se==ss ) error("Could not parse: %s\n", tmp.s); + + sample2sex[ismpl] = ploidy_add_sex(ploidy, ss); + } + if ( hts_close(fp) ) error("Close failed: %s\n", fname); + free(tmp.s); +} + +int init(int argc, char **argv, bcf_hdr_t *in, bcf_hdr_t *out) +{ + int c; + char *tags_str = "GT"; + char *ploidy_fname = NULL, *sex_fname = NULL; + + static struct option loptions[] = + { + {"ploidy",1,0,'p'}, + {"sex",1,0,'s'}, + {"tags",1,0,'t'}, + {0,0,0,0} + }; + while ((c = getopt_long(argc, argv, "?ht:s:p:",loptions,NULL)) >= 0) + { + switch (c) + { + case 'p': ploidy_fname = optarg; break; + case 's': sex_fname = optarg; break; + case 't': tags_str = optarg; break; + case 'h': + case '?': + default: error("%s", usage()); break; + } + } + if ( strcasecmp("GT",tags_str) ) error("Only -t GT is currently supported, sorry\n"); + + n_sample = bcf_hdr_nsamples(in); + sample2sex = (int*) calloc(n_sample,sizeof(int)); + in_hdr = in; + out_hdr = out; + + if ( ploidy_fname ) + ploidy = ploidy_init(ploidy_fname, 2); + else + { + ploidy = ploidy_init_string( + "X 1 60000 M 1\n" + "X 2699521 154931043 M 1\n" + "Y 1 59373566 M 1\n" + "Y 1 59373566 F 0\n" + "MT 1 16569 M 1\n" + "MT 1 16569 F 1\n", 2); + } + if ( !ploidy ) return -1; + + // add default sex in case it was not included + int i, dflt_sex_id = ploidy_add_sex(ploidy, "F"); + for (i=0; ipos+1); + + ploidy_query(ploidy, (char*)bcf_seqname(in_hdr,rec), rec->pos, sex2ploidy,NULL,&max_ploidy); + + ngts /= n_sample; + if ( ngts < max_ploidy ) + { + hts_expand(int32_t,max_ploidy*n_sample,ngt_arr2,gt_arr2); + for (i=0; ipos+1); + } + else if ( ngts!=1 || max_ploidy!=1 ) + { + for (i=0; ipos+1); + } + return rec; +} + + +void destroy(void) +{ + free(gt_arr); + free(gt_arr2); + free(sample2sex); + free(sex2ploidy); + ploidy_destroy(ploidy); +} + + diff --git a/plugins/fixploidy.mk b/plugins/fixploidy.mk new file mode 100644 index 0000000..c476169 --- /dev/null +++ b/plugins/fixploidy.mk @@ -0,0 +1,2 @@ +plugins/fixploidy.so: plugins/fixploidy.c version.h version.c ploidy.h ploidy.c + $(CC) $(PLUGIN_FLAGS) $(CFLAGS) $(EXTRA_CPPFLAGS) $(CPPFLAGS) $(LDFLAGS) -o $@ ploidy.c version.c $< $(LIBS) diff --git a/plugins/fixref.c b/plugins/fixref.c new file mode 100644 index 0000000..25f96e1 --- /dev/null +++ b/plugins/fixref.c @@ -0,0 +1,576 @@ +/* The MIT License + + Copyright (c) 2016 Genome Research Ltd. + + Author: Petr Danecek + + Permission is hereby granted, free of charge, to any person obtaining a copy + of this software and associated documentation files (the "Software"), to deal + in the Software without restriction, including without limitation the rights + to use, copy, modify, merge, publish, distribute, sublicense, and/or sell + copies of the Software, and to permit persons to whom the Software is + furnished to do so, subject to the following conditions: + + The above copyright notice and this permission notice shall be included in + all copies or substantial portions of the Software. + + THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR + IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, + FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE + AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER + LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, + OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN + THE SOFTWARE. + + */ + +/* + Illumina TOP/BOT strand convention causes a lot of pain. This tool + attempts to determine the strand convention and convert it to the + forward reference strand. + + On TOP strand, we can encounter + unambiguous SNPs: + A/G + A/C + ambiguous (context-dependent) SNPs: + C/G + A/T + + On BOT strand: + unambiguous SNPs: + T/G + T/C + ambiguous (context-dependent) SNPs: + T/A + G/C + + + For unambiguous pairs (A/C, A/G, T/C, T/G), the knowledge of reference base + at the SNP position is enough to determine the strand: + + TOP REF -> ALLELES TOP_ON_STRAND + ------------------------------------------- + A/C A or C A/C 1 + " T or G T/G -1 + A/G A or G A/G 1 + " T or C T/C -1 + + + For ambiguous pairs (A/T, C/G), a sequence walking must be performed + (simultaneously upstream and downstream) until the first unambiguous pair + is encountered. The 5' base determines the strand: + + TOP 5'REF_BASE -> ALLELES TOP_ON_STRAND + ------------------------------------------------ + A/T A or T A/T 1 + " C or G T/A -1 + C/G A or T C/G 1 + " C or G G/C -1 + + */ + + +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include "bcftools.h" + +#define MODE_STATS 1 +#define MODE_TOP2FWD 2 +#define MODE_FLIP2FWD 3 +#define MODE_USE_ID 4 + +typedef struct +{ + uint32_t pos; + uint8_t ref:4, alt:4; +} +marker_t; + +KHASH_MAP_INIT_INT(i2m, marker_t) +typedef khash_t(i2m) i2m_t; + +typedef struct +{ + char *dbsnp_fname; + int mode, discard; + bcf_hdr_t *hdr; + faidx_t *fai; + int rid, skip_rid; + i2m_t *i2m; + int32_t *gts, ngts, pos; + uint32_t nsite,nok,nflip,nunresolved,nswap,nflip_swap,nonSNP,nonACGT,nonbiallelic; + uint32_t count[4][4], npos_err, unsorted; +} +args_t; + +args_t args; + +const char *about(void) +{ + return "Fix reference strand orientation, e.g. from Illumina/TOP to fwd.\n"; +} + +const char *usage(void) +{ + return + "\n" + "About: This tool helps to determine and fix strand orientation.\n" + " Currently the following modes are recognised:\n" + " flip .. flips non-ambiguous SNPs and ignores the rest\n" + " id .. swap REF/ALT using the ID column to determine the REF allele\n" + " stats .. collect and print stats\n" + " top .. converts from Illumina TOP strand to fwd\n" + "\n" + " WARNING: Do not use the program blindly, make an effort to\n" + " understand what strand convention your data uses! Make sure\n" + " the reason for mismatching REF alleles is not a different\n" + " reference build!!\n" + "\n" + "Usage: bcftools +fixref [General Options] -- [Plugin Options]\n" + "Options:\n" + " run \"bcftools plugin\" for a list of common options\n" + "\n" + "Plugin options:\n" + " -d, --discard Discard sites which could not be resolved\n" + " -f, --fasta-ref Reference sequence\n" + " -i, --use-id Swap REF/ALT using the ID column to determine the REF allele, implies -m id.\n" + " Download the dbSNP file from\n" + " https://www.ncbi.nlm.nih.gov/variation/docs/human_variation_vcf\n" + " -m, --mode Collect stats (\"stats\") or convert (\"flip\", \"id\", \"top\") [stats]\n" + "\n" + "Examples:\n" + " # run stats\n" + " bcftools +fixref file.bcf -- -f ref.fa\n" + "\n" + " # convert from TOP to fwd\n" + " bcftools +fixref file.bcf -Ob -o out.bcf -- -f ref.fa -m top\n" + "\n" + " # match the REF/ALT alleles based on the ID column, discard unknown sites\n" + " bcftools +fixref file.bcf -Ob -o out.bcf -- -d -f ref.fa -i All_20151104.vcf.gz\n" + "\n" + " # assuming the reference build is correct, just flip to fwd, discarding the rest\n" + " bcftools +fixref file.bcf -Ob -o out.bcf -- -d -f ref.fa -m flip\n" + "\n"; +} + +int init(int argc, char **argv, bcf_hdr_t *in, bcf_hdr_t *out) +{ + memset(&args,0,sizeof(args_t)); + args.skip_rid = -1; + args.hdr = in; + args.mode = MODE_STATS; + char *ref_fname = NULL; + static struct option loptions[] = + { + {"mode",required_argument,NULL,'m'}, + {"discard",no_argument,NULL,'d'}, + {"fasta-ref",required_argument,NULL,'f'}, + {"use-id",required_argument,NULL,'i'}, + {NULL,0,NULL,0} + }; + int c; + while ((c = getopt_long(argc, argv, "?hf:m:di:",loptions,NULL)) >= 0) + { + switch (c) + { + case 'm': + if ( !strcasecmp(optarg,"top") ) args.mode = MODE_TOP2FWD; + else if ( !strcasecmp(optarg,"flip") ) args.mode = MODE_FLIP2FWD; + else if ( !strcasecmp(optarg,"id") ) args.mode = MODE_USE_ID; + else if ( !strcasecmp(optarg,"stats") ) args.mode = MODE_STATS; + else error("The source strand convention not recognised: %s\n", optarg); + break; + case 'i': args.dbsnp_fname = optarg; args.mode = MODE_USE_ID; break; + case 'd': args.discard = 1; break; + case 'f': ref_fname = optarg; break; + case 'h': + case '?': + default: error("%s", usage()); break; + } + } + if ( !ref_fname ) error("Expected the -f option\n"); + args.fai = fai_load(ref_fname); + if ( !args.fai ) error("Failed to load the fai index: %s\n", ref_fname); + + if ( args.mode==MODE_STATS ) return 1; + return 0; +} + +static bcf1_t *set_ref_alt(args_t *args, bcf1_t *rec, const char ref, const char alt, int swap) +{ + rec->d.allele[0][0] = ref; + rec->d.allele[1][0] = alt; + rec->d.shared_dirty |= BCF1_DIRTY_ALS; + + if ( !swap ) return rec; // only fix the alleles, leaving GTs unchanged + + int ngts = bcf_get_genotypes(args->hdr, rec, &args->gts, &args->ngts); + int i, j, nsmpl = bcf_hdr_nsamples(args->hdr); + ngts /= nsmpl; + for (i=0; igts + i*ngts; + for (j=0; jhdr,rec,args->gts,args->ngts); + + return rec; +} + +static inline int nt2int(char nt) +{ + nt = toupper(nt); + if ( nt=='A' ) return 0; + if ( nt=='C' ) return 1; + if ( nt=='G' ) return 2; + if ( nt=='T' ) return 3; + return -1; +} +#define int2nt(x) "ACGT"[x] +#define revint(x) ("3210"[x]-'0') + +static inline uint32_t parse_rsid(char *name) +{ + if ( name[0]!='r' || name[1]!='s' ) + { + name = strstr(name, "rs"); + if ( !name ) return 0; + } + char *tmp; + name += 2; + uint64_t id = strtol(name, &tmp, 10); + if ( tmp==name || *tmp ) return 0; + if ( id > UINT32_MAX ) error("FIXME: the ID is too big for uint32_t: %s\n", name-2); + return id; +} + +static int fetch_ref(args_t *args, bcf1_t *rec) +{ + // Get the reference allele + int len; + char *ref = faidx_fetch_seq(args->fai, (char*)bcf_seqname(args->hdr,rec), rec->pos, rec->pos, &len); + if ( !ref ) + { + if ( faidx_has_seq(args->fai, bcf_seqname(args->hdr,rec))==0 ) + { + fprintf(stderr,"Ignoring sequence \"%s\"\n", bcf_seqname(args->hdr,rec)); + args->skip_rid = rec->rid; + return -2; + } + error("faidx_fetch_seq failed at %s:%d\n", bcf_seqname(args->hdr,rec),rec->pos+1); + } + int ir = nt2int(*ref); + free(ref); + return ir; +} + +static void dbsnp_init(args_t *args, const char *chr) +{ + if ( args->i2m ) kh_destroy(i2m, args->i2m); + args->i2m = kh_init(i2m); + bcf_srs_t *sr = bcf_sr_init(); + if ( bcf_sr_set_regions(sr, chr, 0) != 0 ) goto done; + if ( !bcf_sr_add_reader(sr,args->dbsnp_fname) ) error("Failed to open %s: %s\n", args->dbsnp_fname,bcf_sr_strerror(sr->errnum)); + while ( bcf_sr_next_line(sr) ) + { + bcf1_t *rec = bcf_sr_get_line(sr, 0); + if ( rec->n_allele!=2 ) continue; // skip multiallelic markers + if ( rec->d.allele[0][1]!=0 || rec->d.allele[1][1]!=0 ) continue; // skip non-snps + + int ref = nt2int(rec->d.allele[0][0]); + int alt = nt2int(rec->d.allele[1][0]); + if ( ref<0 || alt<0 ) continue; // non-[ACGT] base + + uint32_t id = parse_rsid(rec->d.id); + if ( !id ) continue; + + int ret, k; + k = kh_put(i2m, args->i2m, id, &ret); + if ( ret<0 ) error("An error occurred while inserting the key %u\n", id); + if ( ret==0 ) continue; // skip ambiguous id + kh_val(args->i2m, k).pos = (uint32_t)rec->pos; + kh_val(args->i2m, k).ref = ref; + kh_val(args->i2m, k).alt = alt; + } +done: + bcf_sr_destroy(sr); +} + +static bcf1_t *dbsnp_check(args_t *args, bcf1_t *rec, int ir, int ia, int ib) +{ + int k, ref,alt,pos; + uint32_t id = parse_rsid(rec->d.id); + if ( !id ) goto no_info; + + k = kh_get(i2m, args->i2m, id); + if ( k==kh_end(args->i2m) ) goto no_info; + + pos = (int)kh_val(args->i2m, k).pos; + if ( pos != rec->pos ) + { + rec->pos = pos; + ir = fetch_ref(args, rec); + args->npos_err++; + } + + ref = kh_val(args->i2m, k).ref; + alt = kh_val(args->i2m, k).alt; + + if ( ref!=ir ) + error("Reference base mismatch at %s:%d .. %c vs %c\n",bcf_seqname(args->hdr,rec),rec->pos+1,int2nt(ref),int2nt(ir)); + + if ( ia==ref && ib==alt ) return rec; + if ( ia==alt && ib==ref ) { args->nswap++; return set_ref_alt(args,rec,int2nt(ib),int2nt(ia),0); } + +no_info: + args->nunresolved++; + return args->discard ? NULL : rec; +} + +bcf1_t *process(bcf1_t *rec) +{ + if ( rec->rid == args.skip_rid ) return NULL; + + bcf1_t *ret = args.mode==MODE_STATS ? NULL : rec; + args.nsite++; + + // Skip non-SNPs + if ( bcf_get_variant_types(rec)!=VCF_SNP ) + { + args.nonSNP++; + return args.discard ? NULL : ret; + } + + // Get the reference allele + int ir = fetch_ref(&args, rec); + if ( ir==-2 ) return NULL; + if ( ir==-1 ) + { + args.nonACGT++; + return args.discard ? NULL : ret; // not A,C,G,T + } + + if ( rec->n_allele!=2 ) + { + // not a biallelic site + args.nonbiallelic++; + return args.discard ? NULL : ret; + } + + int ia = nt2int(rec->d.allele[0][0]); + if ( ia<0 ) + { + // not A,C,G,T + args.nonACGT++; + return args.discard ? NULL : ret; + } + + int ib = nt2int(rec->d.allele[1][0]); + if ( ib<0 ) + { + // not A,C,G,T + args.nonACGT++; + return args.discard ? NULL : ret; + } + + if ( ia==ib ) + { + // should not happen in well-formed VCF + args.nonSNP++; + return args.discard ? NULL : ret; + } + args.count[ia][ib]++; + + if ( ir==ia ) args.nok++; + + if ( args.mode==MODE_USE_ID ) + { + if ( !args.i2m || args.rid!=rec->rid ) + { + args.pos = 0; + args.rid = rec->rid; + dbsnp_init(&args,bcf_seqname(args.hdr,rec)); + } + ret = dbsnp_check(&args, rec, ir,ia,ib); + if ( !args.unsorted && args.pos > rec->pos ) + { + fprintf(stderr, + "Warning: corrected position(s) results in unsorted VCF, for example %s:%d comes after %s:%d\n" + " The standard unix `sort` or `vcf-sort` from vcftools can be used to fix the order.\n", + bcf_seqname(args.hdr,rec),rec->pos+1,bcf_seqname(args.hdr,rec),args.pos); + args.unsorted = 1; + } + args.pos = rec->pos; + return ret; + } + else if ( args.mode==MODE_FLIP2FWD ) + { + int pair = 1 << ia | 1 << ib; + if ( pair==0x9 || pair==0x6 ) // skip ambiguous pairs: A/T or C/G + { + args.nunresolved++; + return args.discard ? NULL : ret; + } + if ( ir==ia ) return ret; + if ( ir==ib ) { args.nswap++; return set_ref_alt(&args,rec,int2nt(ib),int2nt(ia),1); } + if ( ir==revint(ia) ) { args.nflip++; return set_ref_alt(&args,rec,int2nt(revint(ia)),int2nt(revint(ib)),0); } + if ( ir==revint(ib) ) { args.nflip_swap++; return set_ref_alt(&args,rec,int2nt(revint(ib)),int2nt(revint(ia)),1); } + error("FIXME: this should not happen %s:%d\n", bcf_seqname(args.hdr,rec),rec->pos+1); + } + else if ( args.mode==MODE_TOP2FWD ) + { + if ( ia==0 && (ib==1 || ib==2) ) // unambiguous pair: A/C or A/G + { + if ( ir==ia ) return ret; + + int ia_rev = revint(ia); + if ( ir==ia_rev ) // vcfref is A, faref is T, flip + { + args.nflip++; + return set_ref_alt(&args,rec,int2nt(ia_rev),int2nt(revint(ib)),0); + } + if ( ir==ib ) // vcfalt is faref, swap + { + args.nswap++; + return set_ref_alt(&args,rec,int2nt(ib),int2nt(ia),1); + } + assert( ib==revint(ir) ); + + args.nflip_swap++; + return set_ref_alt(&args,rec,int2nt(revint(ib)),int2nt(revint(ia)),1); + } + else // ambiguous pair, sequence walking must be performed + { + int len, win = rec->pos > 100 ? 100 : rec->pos, beg = rec->pos - win, end = rec->pos + win; + char *ref = faidx_fetch_seq(args.fai, (char*)bcf_seqname(args.hdr,rec), beg,end, &len); + if ( !ref ) error("faidx_fetch_seq failed at %s:%d\n", bcf_seqname(args.hdr,rec),rec->pos+1); + if ( end - beg + 1 != len ) error("FIXME: check win=%d,len=%d at %s:%d (%d %d %d)\n", win,len, bcf_seqname(args.hdr,rec),rec->pos+1); + + int i, mid = rec->pos - beg, strand = 0; + for (i=1; i<=win; i++) + { + int ra = nt2int(ref[mid-i]); + int rb = nt2int(ref[mid+i]); + if ( ra<0 || rb<0 || ra==rb ) continue; // skip N's and non-infomative pairs: A/A, C/C, G/G, T/T + int pair = 1 << ra | 1 << rb; + if ( pair==0x9 || pair==0x6 ) continue; // skip ambiguous pairs: A/T or C/G + strand = ra & 0x9 ? 1 : -1; + break; + } + free(ref); + + if ( strand==1 ) + { + if ( ir==ia ) return ret; + if ( ir==ib ) + { + args.nswap++; + return set_ref_alt(&args,rec,int2nt(ib),int2nt(ia),1); + } + } + else if ( strand==-1 ) + { + int ia_rev = revint(ia); + int ib_rev = revint(ib); + if ( ir==ia_rev ) + { + args.nflip++; + return set_ref_alt(&args,rec,int2nt(ia_rev),int2nt(ib_rev),0); + } + if ( ir==ib_rev ) + { + args.nflip_swap++; + return set_ref_alt(&args,rec,int2nt(ib_rev),int2nt(ia_rev),1); + } + } + + args.nunresolved++; + return args.discard ? NULL : ret; + } + } + return ret; +} + +int top_mask[4][4] = +{ + {0,1,1,1}, + {0,0,1,0}, + {0,0,0,0}, + {0,0,0,0}, +}; +int bot_mask[4][4] = +{ + {0,0,0,0}, + {0,0,0,0}, + {0,1,0,0}, + {1,1,1,0}, +}; + +void destroy(void) +{ + uint32_t i,j,tot = 0; + uint32_t top_err = 0, bot_err = 0; + for (i=0; i<4; i++) + { + for (j=0; j<4; j++) + { + tot += args.count[i][j]; + if ( !top_mask[i][j] && args.count[i][j] ) top_err++; + if ( !bot_mask[i][j] && args.count[i][j] ) bot_err++; + } + } + uint32_t nskip = args.nonACGT+args.nonSNP+args.nonbiallelic; + uint32_t ncmp = args.nsite - nskip; + + fprintf(stderr,"# SC, guessed strand convention\n"); + fprintf(stderr,"SC\tTOP-compatible\t%d\n",top_err?0:1); + fprintf(stderr,"SC\tBOT-compatible\t%d\n",bot_err?0:1); + + fprintf(stderr,"# ST, substitution types\n"); + for (i=0; i<4; i++) + { + for (j=0; j<4; j++) + { + if ( i==j ) continue; + fprintf(stderr,"ST\t%c>%c\t%u\t%.1f%%\n", int2nt(i),int2nt(j),args.count[i][j], args.count[i][j]*100./tot); + } + } + fprintf(stderr,"# NS, Number of sites:\n"); + fprintf(stderr,"NS\ttotal \t%u\n", args.nsite); + fprintf(stderr,"NS\tref match \t%u\t%.1f%%\n", args.nok,100.*args.nok/ncmp); + fprintf(stderr,"NS\tref mismatch \t%u\t%.1f%%\n", ncmp-args.nok,100.*(ncmp-args.nok)/ncmp); + if ( args.mode!=MODE_STATS ) + { + fprintf(stderr,"NS\tflipped \t%u\t%.1f%%\n", args.nflip,100.*args.nflip/(args.nsite-nskip)); + fprintf(stderr,"NS\tswapped \t%u\t%.1f%%\n", args.nswap,100.*args.nswap/(args.nsite-nskip)); + fprintf(stderr,"NS\tflip+swap \t%u\t%.1f%%\n", args.nflip_swap,100.*args.nflip_swap/(args.nsite-nskip)); + fprintf(stderr,"NS\tunresolved \t%u\t%.1f%%\n", args.nunresolved,100.*args.nunresolved/(args.nsite-nskip)); + fprintf(stderr,"NS\tfixed pos \t%u\t%.1f%%\n", args.npos_err,100.*args.npos_err/(args.nsite-nskip)); + } + fprintf(stderr,"NS\tskipped \t%u\n", nskip); + fprintf(stderr,"NS\tnon-ACGT \t%u\n", args.nonACGT); + fprintf(stderr,"NS\tnon-SNP \t%u\n", args.nonSNP); + fprintf(stderr,"NS\tnon-biallelic\t%u\n", args.nonbiallelic); + + free(args.gts); + if ( args.fai ) fai_destroy(args.fai); + if ( args.i2m ) kh_destroy(i2m, args.i2m); +} diff --git a/plugins/frameshifts.c b/plugins/frameshifts.c new file mode 100644 index 0000000..5c0e924 --- /dev/null +++ b/plugins/frameshifts.c @@ -0,0 +1,157 @@ +/* plugins/frameshifts.c -- annotates frameshift indels. + + Copyright (C) 2014 Genome Research Ltd. + + Author: Petr Danecek + +Permission is hereby granted, free of charge, to any person obtaining a copy +of this software and associated documentation files (the "Software"), to deal +in the Software without restriction, including without limitation the rights +to use, copy, modify, merge, publish, distribute, sublicense, and/or sell +copies of the Software, and to permit persons to whom the Software is +furnished to do so, subject to the following conditions: + +The above copyright notice and this permission notice shall be included in +all copies or substantial portions of the Software. + +THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL +THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER +LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING +FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER +DEALINGS IN THE SOFTWARE. */ + +#include +#include +#include +#include +#include + +bcf_hdr_t *in_hdr, *out_hdr; +bcf_sr_regions_t *exons; +int32_t *frm = NULL, nfrm = 0; + +const char *about(void) +{ + return + "Annotate frameshift indels.\n"; +} + +const char *usage(void) +{ + return + "\n" + "About: Annotate frameshift indels\n" + "Usage: bcftools +frameshifts [General Options] -- [Plugin Options]\n" + "Options:\n" + " run \"bcftools plugin\" for a list of common options\n" + "\n" + "Plugin options:\n" + " -e, --exons list of exons, see \"--targets-file\" man page entry for details\n" + "\n" + "Example:\n" + " bcftools +frameshifts in.vcf -- -e exons.bed.gz\n" + "\n"; +} + + +int init(int argc, char **argv, bcf_hdr_t *in, bcf_hdr_t *out) +{ + int c; + char *fname = NULL; + + static struct option loptions[] = + { + {"exons",1,0,'e'}, + {0,0,0,0} + }; + while ((c = getopt_long(argc, argv, "e:?h",loptions,NULL)) >= 0) + { + switch (c) + { + case 'e': fname = optarg; break; + case 'h': + case '?': + default: fprintf(stderr,"%s", usage()); exit(1); break; + } + } + if ( !fname ) + { + fprintf(stderr,"Missing the -e option.\n"); + return -1; + } + + in_hdr = in; + out_hdr = out; + + int ret = bcf_hdr_append(out_hdr,"##INFO="); + if ( ret!=0 ) + { + fprintf(stderr,"Error updating the header\n"); + return -1; + } + + exons = bcf_sr_regions_init(fname,1,0,1,2); + if ( !exons ) + { + fprintf(stderr,"Error occurred while reading (was the file compressed with bgzip?): %s\n", fname); + return -1; + } + + return 0; +} + +bcf1_t *process(bcf1_t *rec) +{ + if ( rec->n_allele<2 ) return rec; // not a variant + + int type = bcf_get_variant_types(rec); + if ( !(type&VCF_INDEL) ) return rec; // not an indel + + int i, len = 0; + for (i=1; in_allele; i++) + if ( len > rec->d.var[i].n ) len = rec->d.var[i].n; + + int pos_to = len!=0 ? rec->pos : rec->pos - len; // len is negative + if ( bcf_sr_regions_overlap(exons, bcf_seqname(in_hdr,rec),rec->pos,pos_to) ) return rec; // no overlap + + hts_expand(int32_t,rec->n_allele-1,nfrm,frm); + for (i=1; in_allele; i++) + { + if ( rec->d.var[i].type!=VCF_INDEL ) { frm[i-1] = -1; continue; } + + int len = rec->d.var[i].n, tlen = 0; + if ( len>0 ) + { + // insertion + if ( exons->start <= rec->pos && exons->end > rec->pos ) tlen = abs(len); + } + else if ( exons->start <= rec->pos + abs(len) ) + { + // deletion + tlen = abs(len); + if ( rec->pos < exons->start ) // trim the beginning + tlen -= exons->start - rec->pos + 1; + if ( exons->end < rec->pos + abs(len) ) // trim the end + tlen -= rec->pos + abs(len) - exons->end; + } + if ( tlen ) // there are some deleted/inserted bases in the exon + { + if ( tlen%3 ) frm[i-1] = 1; // out-of-frame + else frm[i-1] = 0; // in-frame + } + else frm[i-1] = -1; // not applicable (is outside) + } + + if ( bcf_update_info_int32(out_hdr,rec,"OOF",frm,rec->n_allele-1)<0 ) { fprintf(stderr, "Could not annotate OOF :-/\n"); exit(1); } + return rec; +} + + +void destroy(void) +{ + bcf_sr_regions_destroy(exons); +} + + diff --git a/plugins/guess-ploidy.c b/plugins/guess-ploidy.c new file mode 100644 index 0000000..7a4fafc --- /dev/null +++ b/plugins/guess-ploidy.c @@ -0,0 +1,568 @@ +/* + Copyright (C) 2016 Genome Research Ltd. + + Author: Petr Danecek + + Permission is hereby granted, free of charge, to any person obtaining a copy + of this software and associated documentation files (the "Software"), to deal + in the Software without restriction, including without limitation the rights + to use, copy, modify, merge, publish, distribute, sublicense, and/or sell + copies of the Software, and to permit persons to whom the Software is + furnished to do so, subject to the following conditions: + + The above copyright notice and this permission notice shall be included in + all copies or substantial portions of the Software. + + THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR + IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, + FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE + AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER + LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, + OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN + THE SOFTWARE. +*/ + +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include "bcftools.h" +#include "filter.h" + +// Logic of the filters: include or exclude sites which match the filters? +#define FLT_INCLUDE 1 +#define FLT_EXCLUDE 2 + +#define GUESS_GT 1 +#define GUESS_PL 2 +#define GUESS_GL 4 + +typedef struct +{ + uint64_t ncount; + double phap, pdip; +} +count_t; + +typedef struct +{ + char *chr; + uint32_t start, end; + count_t *counts; // per-sample counts: counts[isample] +} +stats_t; + +typedef struct +{ + int argc; + char **argv, *af_tag; + double af_dflt; + stats_t stats; + filter_t *filter; + char *filter_str; + int filter_logic; // include or exclude sites which match the filters? One of FLT_INCLUDE/FLT_EXCLUDE + const uint8_t *smpl_pass; + int nsample, verbose, tag, include_indels; + int *counts, ncounts; // number of observed GTs with given ploidy, used when -g is not given + double *tmpf, *pl2p, gt_err_prob; + float *af; + int maf; + int32_t *arr, narr, nfarr; + float *farr; + bcf_srs_t *sr; + bcf_hdr_t *hdr; +} +args_t; + +const char *about(void) +{ + return "Determine sample sex by checking genotype likelihoods in haploid regions.\n"; +} + +static const char *usage_text(void) +{ + return + "\n" + "About: Determine sample sex by checking genotype likelihoods (GL,PL) or genotypes (GT)\n" + " in the non-PAR region of chrX. The HWE is assumed, so given the alternate allele\n" + " frequency fA and the genotype likelihoods pRR,pRA,pAA, the probabilities are\n" + " calculated as\n" + " P(dip) = pRR*(1-fA)^2 + pAA*fA^2 + 2*pRA*(1-fA)*fA\n" + " P(hap) = pRR*(1-fA) + pAA*fA\n" + " When genotype likelihoods are not available, the -e option is used to account\n" + " for genotyping errors with -t GT. The alternate allele frequency fA is estimated\n" + " directly from the data (the default) or can be provided by an INFO tag.\n" + " The results can be visualized using the accompanied guess-ploidy.py script.\n" + " Note that this plugin is intended to replace the former vcf2sex plugin.\n" + "\n" + "Usage: bcftools +guess-ploidy [Plugin Options]\n" + "Plugin options:\n" + " --AF-dflt the default alternate allele frequency [0.5]\n" + " --AF-tag use TAG for allele frequency\n" + " -e, --error-rate probability of GT being wrong (with -t GT) [1e-3]\n" + " --exclude exclude sites for which the expression is true\n" + " -i, --include-indels do not skip indel sites\n" + " --include include only sites for which the expression is true\n" + " -g, --genome shortcut to select nonPAR region for common genomes b37|hg19|b38|hg38\n" + " -r, --regions restrict to comma-separated list of regions\n" + " -R, --regions-file restrict to regions listed in a file\n" + " -t, --tag genotype or genotype likelihoods: GT, PL, GL [PL]\n" + " -v, --verbose verbose output (specify twice to increase verbosity)\n" + "\n" + "Region shortcuts:\n" + " b37 .. -r X:2699521-154931043 # GRCh37 no-chr prefix\n" + " b38 .. -r X:2781480-155701381 # GRCh38 no-chr prefix\n" + " hg19 .. -r chrX:2699521-154931043 # GRCh37 chr prefix\n" + " hg38 .. -r chrX:2781480-155701381 # GRCh38 chr prefix\n" + "\n" + "Examples:\n" + " bcftools +guess-ploidy -g b37 in.vcf.gz\n" + " bcftools +guess-ploidy in.vcf.gz -t GL -r chrX:2699521-154931043\n" + " bcftools view file.vcf.gz -r chrX:2699521-154931043 | bcftools +guess-ploidy\n" + " bcftools +guess-ploidy in.bcf -v > ploidy.txt && guess-ploidy.py ploidy.txt img\n" + "\n"; +} + +static inline int smpl_pass(args_t *args, int ismpl) +{ + if ( !args->smpl_pass ) return 1; + int pass = args->smpl_pass[ismpl]; + if ( args->filter_logic & FLT_EXCLUDE ) pass = pass ? 0 : 1; + if ( pass ) return 1; + return 0; +} + +void process_region_guess(args_t *args) +{ + while ( bcf_sr_next_line(args->sr) ) + { + bcf1_t *rec = bcf_sr_get_line(args->sr,0); + if ( rec->n_allele==1 ) continue; + if ( !args->include_indels && !(bcf_get_variant_types(rec)&VCF_SNP) ) continue; + + if ( args->filter ) + { + int pass = filter_test(args->filter, rec, &args->smpl_pass); + if ( args->filter_logic & FLT_EXCLUDE ) pass = pass ? 0 : 1; + if ( !args->smpl_pass && !pass ) continue; // site-level filtering, not per-sample filtering + } + + double freq[2] = {0,0}, sum; + int ismpl,i; + if ( args->tag & GUESS_GT ) // use GTs to guess the ploidy, considering only one ALT + { + int ngt = bcf_get_genotypes(args->hdr,rec,&args->arr,&args->narr); + if ( ngt<=0 ) continue; + ngt /= args->nsample; + for (ismpl=0; ismplnsample; ismpl++) + { + if ( !smpl_pass(args,ismpl) ) continue; + int32_t *ptr = args->arr + ismpl*ngt; + double *tmp = args->tmpf + ismpl*3; + + if ( ptr[0]==bcf_gt_missing ) + { + tmp[0] = -1; + continue; + } + if ( ptr[1]==bcf_int32_vector_end ) + { + if ( bcf_gt_allele(ptr[0])==0 ) // haploid R + { + tmp[0] = 1 - 2*args->gt_err_prob; + tmp[1] = tmp[2] = args->gt_err_prob; + } + else // haploid A + { + tmp[0] = tmp[1] = args->gt_err_prob; + tmp[2] = 1 - 2*args->gt_err_prob; + } + continue; + } + if ( bcf_gt_allele(ptr[0])==0 && bcf_gt_allele(ptr[1])==0 ) // RR + { + tmp[0] = 1 - 2*args->gt_err_prob; + tmp[1] = tmp[2] = args->gt_err_prob; + } + else if ( bcf_gt_allele(ptr[0])==bcf_gt_allele(ptr[1]) ) // AA + { + tmp[0] = tmp[1] = args->gt_err_prob; + tmp[2] = 1 - 2*args->gt_err_prob; + } + else // RA or hetAA, treating as RA + { + tmp[1] = 1 - 2*args->gt_err_prob; + tmp[0] = tmp[2] = args->gt_err_prob; + } + freq[0] += 2*tmp[0]+tmp[1]; + freq[1] += tmp[1]+2*tmp[2]; + } + } + else if ( args->tag & GUESS_PL ) // use PL guess the ploidy, restrict to first ALT allele + { + int npl = bcf_get_format_int32(args->hdr,rec,"PL",&args->arr,&args->narr); + if ( npl<=0 ) continue; + npl /= args->nsample; + int ndip_gt = rec->n_allele*(rec->n_allele+1)/2; + if ( npl==ndip_gt ) // diploid + { + for (ismpl=0; ismplnsample; ismpl++) + { + if ( !smpl_pass(args,ismpl) ) continue; + int32_t *ptr = args->arr + ismpl*npl; + double *tmp = args->tmpf + ismpl*3; + + // restrict to first ALT + if ( ptr[0]==bcf_int32_missing || ptr[1]==bcf_int32_missing || ptr[2]==bcf_int32_missing ) + { + tmp[0] = -1; + continue; + } + if ( ptr[0]==ptr[1] && ptr[0]==ptr[2] ) // non-informative + { + tmp[0] = -1; + continue; + } + if ( ptr[2]==bcf_int32_vector_end ) + { + tmp[0] = (ptr[0]<0 || ptr[0]>=256) ? args->pl2p[255] : args->pl2p[ptr[0]]; + tmp[1] = args->pl2p[255]; + tmp[2] = (ptr[1]<0 || ptr[1]>=256) ? args->pl2p[255] : args->pl2p[ptr[1]]; + } + else + for (i=0; i<3; i++) + tmp[i] = (ptr[i]<0 || ptr[i]>=256) ? args->pl2p[255] : args->pl2p[ptr[i]]; + + sum = 0; + for (i=0; i<3; i++) sum += tmp[i]; + for (i=0; i<3; i++) tmp[i] /= sum; + + if ( ptr[2]==bcf_int32_vector_end ) + { + freq[0] += tmp[0]; + freq[1] += tmp[2]; + } + else + { + freq[0] += 2*tmp[0]+tmp[1]; + freq[1] += tmp[1]+2*tmp[2]; + } + } + } + else if ( npl==rec->n_allele ) // all samples haploid + { + for (ismpl=0; ismplnsample; ismpl++) + { + if ( !smpl_pass(args,ismpl) ) continue; + int32_t *ptr = args->arr + ismpl*npl; + double *tmp = args->tmpf + ismpl*3; + + // restrict to first ALT + if ( ptr[0]==bcf_int32_missing || ptr[1]==bcf_int32_missing ) + { + tmp[0] = -1; + continue; + } + tmp[0] = (ptr[0]<0 || ptr[0]>=256) ? args->pl2p[255] : args->pl2p[ptr[0]]; + tmp[1] = args->pl2p[255]; + tmp[2] = (ptr[1]<0 || ptr[1]>=256) ? args->pl2p[255] : args->pl2p[ptr[1]]; + + sum = 0; + for (i=0; i<3; i++) sum += tmp[i]; + for (i=0; i<3; i++) tmp[i] /= sum; + + freq[0] += tmp[0]; + freq[1] += tmp[2]; + } + } + else + continue; // neither diploid nor haploid + } + else // use GL + { + int ngl = bcf_get_format_float(args->hdr,rec,"GL",&args->farr,&args->nfarr); + if ( ngl<=0 ) continue; + ngl /= args->nsample; + int ndip_gt = rec->n_allele*(rec->n_allele+1)/2; + if ( ngl==ndip_gt ) // diploid + { + for (ismpl=0; ismplnsample; ismpl++) + { + if ( !smpl_pass(args,ismpl) ) continue; + float *ptr = args->farr + ismpl*ngl; + double *tmp = args->tmpf + ismpl*3; + + // restrict to first ALT + if ( bcf_float_is_missing(ptr[0]) || bcf_float_is_missing(ptr[1]) || bcf_float_is_missing(ptr[2]) ) + { + tmp[0] = -1; + continue; + } + if ( ptr[0]==ptr[1] && ptr[0]==ptr[2] ) // non-informative + { + tmp[0] = -1; + continue; + } + if ( bcf_float_is_vector_end(ptr[2]) ) + { + tmp[0] = pow(10.,ptr[0]); + tmp[1] = 1e-26; // arbitrary small value for a het + tmp[2] = pow(10.,ptr[1]); + } + else + for (i=0; i<3; i++) + tmp[i] = pow(10.,ptr[i]); + + sum = 0; + for (i=0; i<3; i++) sum += tmp[i]; + for (i=0; i<3; i++) tmp[i] /= sum; + + if ( bcf_float_is_vector_end(ptr[2]) ) + { + freq[0] += tmp[0]; + freq[1] += tmp[2]; + } + else + { + freq[0] += 2*tmp[0]+tmp[1]; + freq[1] += tmp[1]+2*tmp[2]; + } + } + } + else if ( ngl==rec->n_allele ) // all samples haploid + { + for (ismpl=0; ismplnsample; ismpl++) + { + if ( !smpl_pass(args,ismpl) ) continue; + float *ptr = args->farr + ismpl*ngl; + double *tmp = args->tmpf + ismpl*3; + + // restrict to first ALT + if ( bcf_float_is_missing(ptr[0]) || bcf_float_is_missing(ptr[1]) ) + { + tmp[0] = -1; + continue; + } + tmp[0] = pow(10.,ptr[0]); + tmp[1] = 1e-26; + tmp[2] = pow(10.,ptr[1]); + + sum = 0; + for (i=0; i<3; i++) sum += tmp[i]; + for (i=0; i<3; i++) tmp[i] /= sum; + + freq[0] += tmp[0]; + freq[1] += tmp[2]; + } + } + else + continue; // neither diploid nor haploid + } + if ( args->af_tag ) + { + int ret = bcf_get_info_float(args->hdr,rec,args->af_tag,&args->af, &args->maf); + if ( ret>0 ) { freq[0] = 1 - args->af[0]; freq[1] = args->af[0]; } + } + + if ( !freq[0] && !freq[1] ) { freq[0] = 1 - args->af_dflt; freq[1] = args->af_dflt; } + sum = freq[0] + freq[1]; + freq[0] /= sum; + freq[1] /= sum; + for (ismpl=0; ismplnsample; ismpl++) + { + if ( !smpl_pass(args,ismpl) ) continue; + count_t *counts = &args->stats.counts[ismpl]; + double *tmp = args->tmpf + ismpl*3; + if ( tmp[0] < 0 ) continue; + double phap = freq[0]*tmp[0] + freq[1]*tmp[2]; + double pdip = freq[0]*freq[0]*tmp[0] + 2*freq[0]*freq[1]*tmp[1] + freq[1]*freq[1]*tmp[2]; + counts->phap += log(phap); + counts->pdip += log(pdip); + counts->ncount++; + if ( args->verbose>1 ) + printf("DBG\t%s\t%d\t%s\t%e\t%e\t%e\t%e\t%e\t%e\n", bcf_seqname(args->hdr,rec),rec->pos+1,bcf_hdr_int2id(args->hdr,BCF_DT_SAMPLE,ismpl), + freq[1],tmp[0],tmp[1],tmp[2],phap,pdip); + } + } +} + +int run(int argc, char **argv) +{ + args_t *args = (args_t*) calloc(1,sizeof(args_t)); + args->tag = GUESS_PL; + args->argc = argc; args->argv = argv; + args->gt_err_prob = 1e-3; + args->af_dflt = 0.5; + char *region = NULL; + int region_is_file = 0; + static struct option loptions[] = + { + {"AF-tag",required_argument,NULL,0}, + {"AF-dflt",required_argument,NULL,1}, + {"exclude",required_argument,NULL,2}, + {"include",required_argument,NULL,3}, + {"verbose",no_argument,NULL,'v'}, + {"include-indels",no_argument,NULL,'i'}, + {"error-rate",required_argument,NULL,'e'}, + {"tag",required_argument,NULL,'t'}, + {"genome",required_argument,NULL,'g'}, + {"regions",required_argument,NULL,'r'}, + {"regions-file",required_argument,NULL,'R'}, + {"background",required_argument,NULL,'b'}, + {NULL,0,NULL,0} + }; + int c; + char *tmp; + while ((c = getopt_long(argc, argv, "vr:R:t:e:ig:",loptions,NULL)) >= 0) + { + switch (c) + { + case 0: args->af_tag = optarg; break; + case 1: + args->af_dflt = strtod(optarg,&tmp); + if ( *tmp ) error("Could not parse: --AF-dflt %s\n", optarg); + break; + case 2: args->filter_str = optarg; args->filter_logic |= FLT_EXCLUDE; break; + case 3: args->filter_str = optarg; args->filter_logic |= FLT_INCLUDE; break; + case 'i': args->include_indels = 1; break; + case 'e': + args->gt_err_prob = strtod(optarg,&tmp); + if ( *tmp ) error("Could not parse: -e %s\n", optarg); + if ( args->gt_err_prob<0 || args->gt_err_prob>1 ) error("Expected value from the interval [0,1]: -e %s\n", optarg); + break; + case 'g': + if ( !strcasecmp(optarg,"b37") ) region = "X:2699521-154931043"; + else if ( !strcasecmp(optarg,"b38") ) region = "X:2781480-155701381"; + else if ( !strcasecmp(optarg,"hg19") ) region = "chrX:2699521-154931043"; + else if ( !strcasecmp(optarg,"hg38") ) region = "chrX:2781480-155701381"; + else error("The argument not recognised, expected --genome b37, b38, hg19 or hg38: %s\n", optarg); + break; + case 'R': region_is_file = 1; + case 'r': region = optarg; break; + case 'v': args->verbose++; break; + case 't': + if ( !strcasecmp(optarg,"GT") ) args->tag = GUESS_GT; + else if ( !strcasecmp(optarg,"PL") ) args->tag = GUESS_PL; + else if ( !strcasecmp(optarg,"GL") ) args->tag = GUESS_GL; + else error("The argument not recognised, expected --tag GT, PL or GL: %s\n", optarg); + break; + case 'h': + case '?': + default: error("%s", usage_text()); break; + } + } + if ( args->filter_logic == (FLT_EXCLUDE|FLT_INCLUDE) ) error("Only one of --include or --exclude can be given.\n"); + + char *fname = NULL; + if ( optind==argc ) + { + if ( !isatty(fileno((FILE *)stdin)) ) fname = "-"; // reading from stdin + else { error(usage_text()); } + } + else if ( optind+1!=argc ) error(usage_text()); + else fname = argv[optind]; + + args->sr = bcf_sr_init(); + if ( strcmp("-",fname) ) + { + if ( region ) + { + args->sr->require_index = 1; + if ( bcf_sr_set_regions(args->sr, region, region_is_file)<0 ) + error("Failed to read the regions: %s\n",region); + } + } + else + { + if ( region ) + { + if ( bcf_sr_set_targets(args->sr, region, region_is_file, 0)<0 ) + error("Failed to read the targets: %s\n",region); + } + } + if ( !bcf_sr_add_reader(args->sr,fname) ) error("Error: %s\n", bcf_sr_strerror(args->sr->errnum)); + args->hdr = args->sr->readers[0].header; + args->nsample = bcf_hdr_nsamples(args->hdr); + args->stats.counts = (count_t*) calloc(args->nsample,sizeof(count_t)); + + if ( args->filter_str ) + args->filter = filter_init(args->hdr, args->filter_str); + + if ( args->af_tag && !bcf_hdr_idinfo_exists(args->hdr,BCF_HL_INFO,bcf_hdr_id2int(args->hdr,BCF_DT_ID,args->af_tag)) ) + error("No such INFO tag: %s\n", args->af_tag); + + if ( args->tag&GUESS_PL && bcf_hdr_id2int(args->hdr, BCF_DT_ID, "PL")<0 ) + { + fprintf(stderr, "Warning: PL tag not found in header, switching to GL\n"); + args->tag = GUESS_GL; + } + + if ( args->tag&GUESS_GL && bcf_hdr_id2int(args->hdr, BCF_DT_ID, "GL")<0 ) + { + fprintf(stderr, "Warning: GL tag not found in header, switching to GT\n"); + args->tag = GUESS_GT; + } + + if ( args->tag&GUESS_GT && bcf_hdr_id2int(args->hdr, BCF_DT_ID, "GT")<0 ) + error("Error: GT tag not found in header\n"); + + int i; + if ( args->tag&GUESS_PL ) + { + args->pl2p = (double*) calloc(256,sizeof(double)); + for (i=0; i<256; i++) args->pl2p[i] = pow(10., -i/10.); + } + if ( args->tag&GUESS_PL || args->tag&GUESS_GL || args->tag&GUESS_GT ) + args->tmpf = (double*) malloc(sizeof(*args->tmpf)*3*args->nsample); + + if ( args->verbose ) + { + printf("# This file was produced by: bcftools +guess-ploidy(%s+htslib-%s)\n", bcftools_version(),hts_version()); + printf("# The command line was:\tbcftools +%s", args->argv[0]); + for (i=1; iargc; i++) + printf(" %s",args->argv[i]); + printf("\n"); + printf("# [1]SEX\t[2]Sample\t[3]Predicted sex\t[4]log P(Haploid)/nSites\t[5]log P(Diploid)/nSites\t[6]nSites\t[7]Score: F < 0 < M ($4-$5)\n"); + if ( args->verbose>1 ) + printf("# [1]DBG\t[2]Chr\t[3]Pos\t[4]Sample\t[5]AF\t[6]pRR\t[7]pRA\t[8]pAA\t[9]P(Haploid)\t[10]P(Diploid)\n"); + } + + process_region_guess(args); + + for (i=0; insample; i++) + { + double phap = args->stats.counts[i].ncount ? args->stats.counts[i].phap / args->stats.counts[i].ncount : 0.5; + double pdip = args->stats.counts[i].ncount ? args->stats.counts[i].pdip / args->stats.counts[i].ncount : 0.5; + char predicted_sex = 'U'; + if (phap>pdip) predicted_sex = 'M'; + else if (phapverbose ) + { + printf("SEX\t%s\t%c\t%f\t%f\t%"PRId64"\t%f\n", args->hdr->samples[i],predicted_sex, + phap,pdip,args->stats.counts[i].ncount,phap-pdip); + } + else + printf("%s\t%c\n", args->hdr->samples[i],predicted_sex); + } + + if ( args->filter ) + filter_destroy(args->filter); + + bcf_sr_destroy(args->sr); + free(args->pl2p); + free(args->tmpf); + free(args->counts); + free(args->stats.counts); + free(args->arr); + free(args->farr); + free(args->af); + free(args); + return 0; +} diff --git a/plugins/impute-info.c b/plugins/impute-info.c new file mode 100644 index 0000000..42d4eb4 --- /dev/null +++ b/plugins/impute-info.c @@ -0,0 +1,165 @@ +/* plugins/impute-info.c -- adds info metrics to a VCF file. + + Copyright (C) 2015-2016 Genome Research Ltd. + + Author: Shane McCarthy + +Permission is hereby granted, free of charge, to any person obtaining a copy +of this software and associated documentation files (the "Software"), to deal +in the Software without restriction, including without limitation the rights +to use, copy, modify, merge, publish, distribute, sublicense, and/or sell +copies of the Software, and to permit persons to whom the Software is +furnished to do so, subject to the following conditions: + +The above copyright notice and this permission notice shall be included in +all copies or substantial portions of the Software. + +THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL +THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER +LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING +FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER +DEALINGS IN THE SOFTWARE. */ + + +/* + +Marchini & Howie, Nature Genetics, 11 (July 2010) + +Let G_ij in {0,1,2} be the genotype of the ith individual at the +jth SNP in a study cohort of N samples. Let + + p_ijk = P(G_ij = k | H,G) + +be the probability that the genotype at the jth SNP of the ith +individual is k. + +Let the expected allele dosage for the genotype at the jth SNP +of the ith individual be + + e_ij = p_ij1 + 2 * p_ij2 + +and define + + f_ij = p_ij1 + 4 * p_ij2 + +Let theta_j denote the (unknown) population allele frequency of the jth SNP +with: + + theta_j = SUM[i=1..N] e_ij / 2 * N + +The IMPUTE2 information measure is then: + + if theta_j in (0,1): + I(theta_j) = 1 - SUM[i=1..N](f_ij - e_ij^2) / 2 * N * theta_j * (1 - theta_j) + else: + I(theta_j) = 1 + +*/ + +#include +#include +#include +#include +#include + +const char *about(void) +{ + return "Add imputation information metrics to the INFO field based on selected FORMAT tags.\n"; +} + +const char *usage(void) +{ + return + "\n" + "About: Add imputation information metrics to the INFO field based\n" + " on selected FORMAT tags. Only the IMPUTE2 INFO metric from\n" + " FORMAT/GP tags is currently available.\n" + "Usage: bcftools +impute-info [General Options] -- [Plugin Options]\n" + "Options:\n" + " run \"bcftools plugin\" for a list of common options\n" + "\n" + // "Plugin options:\n" + // " -i, --info information metrics to add [INFO]\n" // [BEAGLE_R2,MACH_R2] + // " -t, --tags VCF tags to determine the information from [GP]\n" + // "\n" + "Example:\n" + " bcftools +impute-info in.vcf\n" + "\n"; +} + +bcf_hdr_t *in_hdr = NULL, *out_hdr = NULL; +int gp_type = BCF_HT_REAL; +uint8_t *buf = NULL; +int nbuf = 0; // NB: number of elements, not bytes +int nrec = 0, nskip_gp = 0, nskip_dip = 0; + +int init(int argc, char **argv, bcf_hdr_t *in, bcf_hdr_t *out) +{ + in_hdr = in; + out_hdr = out; + bcf_hdr_append(out_hdr,"##INFO="); + return 0; +} + +bcf1_t *process(bcf1_t *rec) +{ + int nval = 0, i, j, nret = bcf_get_format_values(in_hdr,rec,"GP",(void**)&buf,&nbuf,gp_type); + if ( nret<0 ) + { + if (!nskip_gp) fprintf(stderr, "[impute-info.c] Warning: info tag not added to sites without GP tag\n"); + nskip_gp++; + return rec; // require FORMAT/GP tag, return site unchanged + } + + nret /= rec->n_sample; + if ( nret != 3 ) + { + if (!nskip_dip) fprintf(stderr, "[impute-info.c] Warning: info tag not added to sites that are not biallelic diploid\n"); + nskip_dip++; + return rec; // require biallelic diploid, return site unchanged + } + + double esum = 0, e2sum = 0, fsum = 0; + #define BRANCH(type_t,is_missing,is_vector_end) \ + { \ + type_t *ptr = (type_t*) buf; \ + for (i=0; in_sample; i++) \ + { \ + double vals[3] = {0,0,0}; \ + for (j=0; j0 && theta<1) ? (float)(1 - (fsum - e2sum) / (2 * (double)nval * theta * (1.0 - theta))) : 1; + + bcf_update_info_float(out_hdr, rec, "INFO", &info, 1); + nrec++; + return rec; +} + + +void destroy(void) +{ + fprintf(stderr,"Lines total/info-added/unchanged-no-tag/unchanged-not-biallelic-diploid:\t%d/%d/%d/%d\n", nrec+nskip_gp+nskip_dip, nrec, nskip_gp, nskip_dip); + free(buf); +} diff --git a/plugins/isecGT.c b/plugins/isecGT.c new file mode 100644 index 0000000..e5f50ee --- /dev/null +++ b/plugins/isecGT.c @@ -0,0 +1,177 @@ +/* + Copyright (C) 2016 Genome Research Ltd. + + Author: Petr Danecek + + Permission is hereby granted, free of charge, to any person obtaining a copy + of this software and associated documentation files (the "Software"), to deal + in the Software without restriction, including without limitation the rights + to use, copy, modify, merge, publish, distribute, sublicense, and/or sell + copies of the Software, and to permit persons to whom the Software is + furnished to do so, subject to the following conditions: + + The above copyright notice and this permission notice shall be included in + all copies or substantial portions of the Software. + + THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR + IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, + FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE + AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER + LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, + OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN + THE SOFTWARE. +*/ + +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include "bcftools.h" +#include "smpl_ilist.h" + +typedef struct +{ + int argc, output_type, regions_is_file, targets_is_file; + char **argv, *output_fname, *regions_list, *targets_list; + int32_t *arr_a, narr_a, *arr_b, narr_b; + bcf_srs_t *sr; + bcf_hdr_t *hdr_a, *hdr_b; + htsFile *out_fh; +} +args_t; + +const char *about(void) +{ + return "Compare two files and set non-identical genotypes to missing.\n"; +} + +static const char *usage_text(void) +{ + return + "\n" + "About: Compare two files and set non-identical genotypes in the first file to missing.\n" + "\n" + "Usage: bcftools +isecGT [Plugin Options]\n" + "Plugin options:\n" + " -o, --output write output to a file [standard output]\n" + " -O, --output-type 'b' compressed BCF; 'u' uncompressed BCF; 'z' compressed VCF; 'v' uncompressed VCF [v]\n" + " -r, --regions restrict to comma-separated list of regions\n" + " -R, --regions-file restrict to regions listed in a file\n" + " -t, --targets similar to -r but streams rather than index-jumps\n" + " -T, --targets-file similar to -R but streams rather than index-jumps\n" + "\n"; +} + +int run(int argc, char **argv) +{ + args_t *args = (args_t*) calloc(1,sizeof(args_t)); + args->output_fname = "-"; + args->output_type = FT_VCF; + static struct option loptions[] = + { + {"regions",required_argument,NULL,'r'}, + {"regions-file",required_argument,NULL,'R'}, + {"targets",required_argument,NULL,'t'}, + {"targets-file",required_argument,NULL,'T'}, + {"output",required_argument,NULL,'o'}, + {"output-type",required_argument,NULL,'O'}, + {NULL,0,NULL,0} + }; + int c; + while ((c = getopt_long(argc, argv, "o:O:r:R:t:T:",loptions,NULL)) >= 0) + { + switch (c) + { + case 'o': args->output_fname = optarg; break; + case 'O': + switch (optarg[0]) { + case 'b': args->output_type = FT_BCF_GZ; break; + case 'u': args->output_type = FT_BCF; break; + case 'z': args->output_type = FT_VCF_GZ; break; + case 'v': args->output_type = FT_VCF; break; + default: error("The output type \"%s\" not recognised\n", optarg); + } + break; + case 'r': args->regions_list = optarg; break; + case 'R': args->regions_list = optarg; args->regions_is_file = 1; break; + case 't': args->targets_list = optarg; break; + case 'T': args->targets_list = optarg; args->targets_is_file = 1; break; + case 'h': + case '?': + default: error("%s", usage_text()); break; + } + } + + if ( optind+2!=argc ) error(usage_text()); + + args->sr = bcf_sr_init(); + args->sr->require_index = 1; + if ( args->regions_list ) + { + if ( bcf_sr_set_regions(args->sr, args->regions_list, args->regions_is_file)<0 ) + error("Failed to read the regions: %s\n", args->regions_list); + } + if ( args->targets_list ) + { + if ( bcf_sr_set_targets(args->sr, args->targets_list, args->targets_is_file, 0)<0 ) + error("Failed to read the targets: %s\n", args->targets_list); + args->sr->collapse |= COLLAPSE_BOTH; + } + if ( !bcf_sr_add_reader(args->sr,argv[optind]) ) error("Error opening %s: %s\n", argv[optind],bcf_sr_strerror(args->sr->errnum)); + if ( !bcf_sr_add_reader(args->sr,argv[optind+1]) ) error("Error opening %s: %s\n", argv[optind+1],bcf_sr_strerror(args->sr->errnum)); + args->hdr_a = bcf_sr_get_header(args->sr,0); + args->hdr_b = bcf_sr_get_header(args->sr,1); + smpl_ilist_t *smpl = smpl_ilist_map(args->hdr_a, args->hdr_b, SMPL_STRICT); + args->out_fh = hts_open(args->output_fname, hts_bcf_wmode(args->output_type)); + if ( args->out_fh == NULL ) error("Can't write to \"%s\": %s\n", args->output_fname, strerror(errno)); + bcf_hdr_write(args->out_fh, args->hdr_a); + + while ( bcf_sr_next_line(args->sr) ) + { + if ( !bcf_sr_has_line(args->sr,0) ) continue; + if ( !bcf_sr_has_line(args->sr,1) ) + { + bcf_write(args->out_fh, args->hdr_a, bcf_sr_get_line(args->sr,0)); + continue; + } + + bcf1_t *line_a = bcf_sr_get_line(args->sr,0); + bcf1_t *line_b = bcf_sr_get_line(args->sr,1); + int ngt_a = bcf_get_genotypes(args->hdr_a, line_a, &args->arr_a, &args->narr_a); + int ngt_b = bcf_get_genotypes(args->hdr_b, line_b, &args->arr_b, &args->narr_b); + assert( ngt_a==ngt_b ); // todo + ngt_a /= smpl->n; + ngt_b /= smpl->n; + int i, j, dirty = 0; + for (i=0; in; i++) + { + int32_t *a = args->arr_a + i*ngt_a; + int32_t *b = args->arr_b + smpl->idx[i]*ngt_b; + for (j=0; jhdr_a, line_a, args->arr_a, ngt_a*smpl->n); + bcf_write(args->out_fh, args->hdr_a, line_a); + } + + if ( hts_close(args->out_fh)!=0 ) error("Close failed: %s\n",args->output_fname); + smpl_ilist_destroy(smpl); + bcf_sr_destroy(args->sr); + free(args->arr_a); + free(args->arr_b); + free(args); + return 0; +} + diff --git a/plugins/mendelian.c b/plugins/mendelian.c new file mode 100644 index 0000000..e8ae8e5 --- /dev/null +++ b/plugins/mendelian.c @@ -0,0 +1,252 @@ +/* The MIT License + + Copyright (c) 2015 Genome Research Ltd. + + Author: Petr Danecek + + Permission is hereby granted, free of charge, to any person obtaining a copy + of this software and associated documentation files (the "Software"), to deal + in the Software without restriction, including without limitation the rights + to use, copy, modify, merge, publish, distribute, sublicense, and/or sell + copies of the Software, and to permit persons to whom the Software is + furnished to do so, subject to the following conditions: + + The above copyright notice and this permission notice shall be included in + all copies or substantial portions of the Software. + + THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR + IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, + FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE + AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER + LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, + OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN + THE SOFTWARE. + + */ + +#include +#include +#include +#include +#include +#include +#include +#include +#include "bcftools.h" + +#define MODE_COUNT 1 +#define MODE_LIST_GOOD 2 +#define MODE_LIST_BAD 4 +#define MODE_DELETE 8 + +typedef struct +{ + int nok, nbad; + int imother,ifather,ichild; +} +trio_t; + +typedef struct _args_t +{ + bcf_hdr_t *hdr; + int32_t *gt_arr; + int mode; + int ngt_arr, nrec; + trio_t *trios; + int ntrios; +} +args_t; + +static args_t args; + +const char *about(void) +{ + return "Count Mendelian consistent / inconsistent genotypes.\n"; +} + +const char *usage(void) +{ + return + "\n" + "About: Count Mendelian consistent / inconsistent genotypes.\n" + "Usage: bcftools +mendelian [General Options] -- [Plugin Options]\n" + "Options:\n" + " run \"bcftools plugin\" for a list of common options\n" + "\n" + "Plugin options:\n" + " -c, --count count the number of consistent sites\n" + " -d, --delete delete inconsistent genotypes (set to \"./.\")\n" + " -l, --list [+x] list consistent (+) or inconsistent (x) sites\n" + " -t, --trio names of mother, father and the child\n" + " -T, --trio-file list of trios, one per line\n" + "\n" + "Example:\n" + " bcftools +mendelian in.vcf -- -t Mother,Father,Child -c\n" + "\n"; +} + +int init(int argc, char **argv, bcf_hdr_t *in, bcf_hdr_t *out) +{ + char *trio_samples = NULL, *trio_file = NULL; + memset(&args,0,sizeof(args_t)); + args.hdr = in; + args.mode = 0; + + static struct option loptions[] = + { + {"trio",1,0,'t'}, + {"trio-file",1,0,'T'}, + {"delete",0,0,'d'}, + {"list",1,0,'l'}, + {"count",0,0,'c'}, + {0,0,0,0} + }; + int c; + while ((c = getopt_long(argc, argv, "?ht:T:l:cd",loptions,NULL)) >= 0) + { + switch (c) + { + case 'd': args.mode |= MODE_DELETE; break; + case 'c': args.mode |= MODE_COUNT; break; + case 'l': + if ( !strcmp("+",optarg) ) args.mode |= MODE_LIST_GOOD; + else if ( !strcmp("x",optarg) ) args.mode |= MODE_LIST_BAD; + else error("The argument not recognised: --list %s\n", optarg); + break; + case 't': trio_samples = optarg; break; + case 'T': trio_file = optarg; break; + case 'h': + case '?': + default: error("%s", usage()); break; + } + } + if ( optind != argc ) error(usage()); + if ( !trio_samples && !trio_file ) error("Expected the -t/T option\n"); + if ( !args.mode ) error("Expected one of the -c, -d or -l options\n"); + if ( args.mode&MODE_DELETE && !(args.mode&(MODE_LIST_GOOD|MODE_LIST_BAD)) ) args.mode |= MODE_LIST_GOOD|MODE_LIST_BAD; + + int i, n = 0; + char **list; + if ( trio_samples ) + { + args.ntrios = 1; + args.trios = (trio_t*) calloc(1,sizeof(trio_t)); + list = hts_readlist(trio_samples, 0, &n); + if ( n!=3 ) error("Expected three sample names with -t\n"); + args.trios[0].imother = bcf_hdr_id2int(args.hdr, BCF_DT_SAMPLE, list[0]); + args.trios[0].ifather = bcf_hdr_id2int(args.hdr, BCF_DT_SAMPLE, list[1]); + args.trios[0].ichild = bcf_hdr_id2int(args.hdr, BCF_DT_SAMPLE, list[2]); + for (i=0; iimother]; + b = args.gt_arr[2*trio->imother+1]; + c = args.gt_arr[2*trio->ifather]; + d = args.gt_arr[2*trio->ifather+1]; + e = args.gt_arr[2*trio->ichild]; + f = args.gt_arr[2*trio->ichild+1]; + if ( bcf_gt_is_missing(a) || bcf_gt_is_missing(b) ) continue; + if ( bcf_gt_is_missing(c) || bcf_gt_is_missing(d) ) continue; + if ( bcf_gt_is_missing(e) || bcf_gt_is_missing(f) ) continue; + + mother = (1<nok++; + } + else + { + trio->nbad++; + has_bad = 1; + if ( args.mode&MODE_DELETE ) + { + args.gt_arr[2*trio->imother] = bcf_gt_missing; + args.gt_arr[2*trio->imother+1] = bcf_gt_missing; + args.gt_arr[2*trio->ifather] = bcf_gt_missing; + args.gt_arr[2*trio->ifather+1] = bcf_gt_missing; + args.gt_arr[2*trio->ichild] = bcf_gt_missing; + args.gt_arr[2*trio->ichild+1] = bcf_gt_missing; + needs_update = 1; + } + } + } + + if ( needs_update && bcf_update_genotypes(args.hdr,rec,args.gt_arr,ngt) ) + error("Could not update GT field at %s:%d\n", bcf_seqname(args.hdr,rec),rec->pos+1); + + if ( args.mode&MODE_DELETE ) return rec; + if ( args.mode&MODE_LIST_GOOD ) return has_bad ? NULL : rec; + if ( args.mode&MODE_LIST_BAD ) return has_bad ? rec : NULL; + + return NULL; +} + +void destroy(void) +{ + int i; + fprintf(stderr,"# [1]nOK\t[2]nBad\t[3]nSkipped\t[4]Trio\n"); + for (i=0; inok,trio->nbad,args.nrec-(trio->nok+trio->nbad), + bcf_hdr_int2id(args.hdr, BCF_DT_SAMPLE, trio->imother), + bcf_hdr_int2id(args.hdr, BCF_DT_SAMPLE, trio->ifather), + bcf_hdr_int2id(args.hdr, BCF_DT_SAMPLE, trio->ichild) + ); + } + free(args.gt_arr); + free(args.trios); +} + + + diff --git a/plugins/missing2ref.c b/plugins/missing2ref.c new file mode 100644 index 0000000..c4fb6ab --- /dev/null +++ b/plugins/missing2ref.c @@ -0,0 +1,144 @@ +/* plugins/missing2ref.c -- sets missing genotypes to reference allele. + + Copyright (C) 2014 Genome Research Ltd. + + Author: Petr Danecek + +Permission is hereby granted, free of charge, to any person obtaining a copy +of this software and associated documentation files (the "Software"), to deal +in the Software without restriction, including without limitation the rights +to use, copy, modify, merge, publish, distribute, sublicense, and/or sell +copies of the Software, and to permit persons to whom the Software is +furnished to do so, subject to the following conditions: + +The above copyright notice and this permission notice shall be included in +all copies or substantial portions of the Software. + +THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL +THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER +LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING +FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER +DEALINGS IN THE SOFTWARE. */ + +#include +#include +#include +#include +#include +#include + +bcf_hdr_t *in_hdr, *out_hdr; +int32_t *gts = NULL, mgts = 0; +int *arr = NULL, marr = 0; +uint64_t nchanged = 0; +int new_gt = bcf_gt_unphased(0); +int use_major = 0; + +const char *about(void) +{ + return "Set missing genotypes (\"./.\") to ref or major allele (\"0/0\" or \"0|0\").\n"; +} + +const char *usage(void) +{ + return + "\n" + "About: Set missing genotypes\n" + "Usage: bcftools +missing2ref [General Options] -- [Plugin Options]\n" + "Options:\n" + " run \"bcftools plugin\" for a list of common options\n" + "\n" + "Plugin options:\n" + " -p, --phased Set to \"0|0\" \n" + " -m, --major Set to major allele \n" + "\n" + "Example:\n" + " bcftools +missing2ref in.vcf -- -p\n" + " bcftools +missing2ref in.vcf -- -p -m\n" + "\n"; +} + + +int init(int argc, char **argv, bcf_hdr_t *in, bcf_hdr_t *out) +{ + int c; + static struct option loptions[] = + { + {"phased",0,0,'p'}, + {"major",0,0,'m'}, + {0,0,0,0} + }; + while ((c = getopt_long(argc, argv, "mp?h",loptions,NULL)) >= 0) + { + switch (c) + { + case 'p': new_gt = bcf_gt_phased(0); break; + case 'm': use_major = 1; break; + case 'h': + case '?': + default: fprintf(stderr,"%s", usage()); exit(1); break; + } + } + in_hdr = in; + out_hdr = out; + return 0; +} + +bcf1_t *process(bcf1_t *rec) +{ + int ngts = bcf_get_genotypes(in_hdr, rec, >s, &mgts); + int i, changed = 0; + + // Calculating allele frequency for each allele and determining major allele + // only do this if use_major is true + int majorAllele = -1; + int maxAC = -1; + int an = 0; + if(use_major == 1){ + hts_expand(int,rec->n_allele,marr,arr); + int ret = bcf_calc_ac(in_hdr,rec,arr,BCF_UN_FMT); + if(ret > 0){ + for(i=0; i < rec->n_allele; ++i){ + an += arr[i]; + if(*(arr+i) > maxAC){ + maxAC = *(arr+i); + majorAllele = i; + } + } + } + else{ + fprintf(stderr,"Warning: Could not calculate allele count at position %d\n", rec->pos); + exit(1); + } + + // replacing new_gt by major allele + if(bcf_gt_is_phased(new_gt)) + new_gt = bcf_gt_phased(majorAllele); + else + new_gt = bcf_gt_unphased(majorAllele); + } + + // replace gts + for (i=0; i + +Permission is hereby granted, free of charge, to any person obtaining a copy +of this software and associated documentation files (the "Software"), to deal +in the Software without restriction, including without limitation the rights +to use, copy, modify, merge, publish, distribute, sublicense, and/or sell +copies of the Software, and to permit persons to whom the Software is +furnished to do so, subject to the following conditions: + +The above copyright notice and this permission notice shall be included in +all copies or substantial portions of the Software. + +THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL +THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER +LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING +FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER +DEALINGS IN THE SOFTWARE. */ + +#include +#include +#include +#include +#include +#include +#include "bcftools.h" +#include "filter.h" + +// Logic of the filters: include or exclude sites which match the filters? +#define FLT_INCLUDE 1 +#define FLT_EXCLUDE 2 + +bcf_hdr_t *in_hdr, *out_hdr; +int32_t *gts = NULL, mgts = 0; +int *arr = NULL, marr = 0; +uint64_t nchanged = 0; +int tgt_mask = 0, new_mask = 0, new_gt = 0; +filter_t *filter = NULL; +char *filter_str = NULL; +int filter_logic = 0; +const uint8_t *smpl_pass = NULL; + +#define GT_MISSING 1 +#define GT_PARTIAL (1<<1) +#define GT_REF (1<<2) +#define GT_MAJOR (1<<3) +#define GT_PHASED (1<<4) +#define GT_UNPHASED (1<<5) +#define GT_ALL (1<<6) +#define GT_QUERY (1<<7) + +const char *about(void) +{ + return "Set genotypes: partially missing to missing, missing to ref/major allele, etc.\n"; +} + +const char *usage(void) +{ + return + "About: Sets genotypes. The target genotypes can be specified as:\n" + " ./. .. completely missing (\".\" or \"./.\", depending on ploidy)\n" + " ./x .. partially missing (e.g., \"./0\" or \".|1\" but not \"./.\")\n" + " . .. partially or completely missing\n" + " a .. all genotypes\n" + " q .. select genotypes using -i/-e options\n" + " and the new genotype can be one of:\n" + " . .. missing (\".\" or \"./.\", keeps ploidy)\n" + " 0 .. reference allele\n" + " M .. major allele\n" + " p .. phased genotype\n" + " u .. unphase genotype and sort by allele (1|0 becomes 0/1)\n" + "Usage: bcftools +setGT [General Options] -- [Plugin Options]\n" + "Options:\n" + " run \"bcftools plugin\" for a list of common options\n" + "\n" + "Plugin options:\n" + " -e, --exclude Exclude a genotype if true (requires -t q)\n" + " -i, --include include a genotype if true (requires -t q)\n" + " -n, --new-gt Genotypes to set, see above\n" + " -t, --target-gt Genotypes to change, see above\n" + "\n" + "Example:\n" + " # set missing genotypes (\"./.\") to phased ref genotypes (\"0|0\")\n" + " bcftools +setGT in.vcf -- -t . -n 0p\n" + "\n" + " # set missing genotypes with DP>0 and GQ>20 to ref genotypes (\"0/0\")\n" + " bcftools +setGT in.vcf -- -t q -n 0 -i 'GT=\".\" && FMT/DP>0 && GQ>20'\n" + "\n" + " # set partially missing genotypes to completely missing\n" + " bcftools +setGT in.vcf -- -t ./x -n .\n" + "\n"; +} + + +int init(int argc, char **argv, bcf_hdr_t *in, bcf_hdr_t *out) +{ + int c; + static struct option loptions[] = + { + {"include",required_argument,NULL,'i'}, + {"exclude",required_argument,NULL,'e'}, + {"new-gt",required_argument,NULL,'n'}, + {"target-gt",required_argument,NULL,'t'}, + {NULL,0,NULL,0} + }; + while ((c = getopt_long(argc, argv, "?hn:t:i:e:",loptions,NULL)) >= 0) + { + switch (c) + { + case 'i': filter_str = optarg; filter_logic = FLT_INCLUDE; break; + case 'e': filter_str = optarg; filter_logic = FLT_EXCLUDE; break; + case 'n': new_mask = bcf_gt_phased(0); + if ( strchr(optarg,'.') ) new_mask |= GT_MISSING; + if ( strchr(optarg,'0') ) new_mask |= GT_REF; + if ( strchr(optarg,'M') ) new_mask |= GT_MAJOR; + if ( strchr(optarg,'p') ) new_mask |= GT_PHASED; + if ( strchr(optarg,'u') ) new_mask |= GT_UNPHASED; + if ( new_mask==0 ) error("Unknown parameter to --new-gt: %s\n", optarg); + break; + case 't': + if ( !strcmp(optarg,".") ) tgt_mask |= GT_MISSING|GT_PARTIAL; + if ( !strcmp(optarg,"./x") ) tgt_mask |= GT_PARTIAL; + if ( !strcmp(optarg,"./.") ) tgt_mask |= GT_MISSING; + if ( !strcmp(optarg,"a") ) tgt_mask |= GT_ALL; + if ( !strcmp(optarg,"q") ) tgt_mask |= GT_QUERY; + if ( !strcmp(optarg,"?") ) tgt_mask |= GT_QUERY; // for backward compatibility + if ( tgt_mask==0 ) error("Unknown parameter to --target-gt: %s\n", optarg); + break; + case 'h': + case '?': + default: fprintf(stderr,"%s", usage()); exit(1); break; + } + } + in_hdr = in; + out_hdr = out; + + if ( !new_mask ) error("Expected -n option\n"); + if ( !tgt_mask ) error("Expected -t option\n"); + + if ( new_mask & GT_MISSING ) new_gt = bcf_gt_missing; + if ( new_mask & GT_REF ) new_gt = new_mask>_PHASED ? bcf_gt_phased(0) : bcf_gt_unphased(0); + + if ( filter_str && tgt_mask!=GT_QUERY ) error("Expected -t? with -i/-e\n"); + if ( !filter_str && tgt_mask>_QUERY ) error("Expected -i/-e with -t?\n"); + if ( filter_str ) filter = filter_init(in,filter_str); + + return 0; +} + +static inline int unphase_gt(int32_t *ptr, int ngts) +{ + int j, changed = 0; + for (j=0; j0 && ptr[l-1]>x ) + { + ptr[l] = ptr[l-1]; + l--; + } + ptr[l] = x; + } + return changed; +} +static inline int set_gt(int32_t *ptr, int ngts, int gt) +{ + int j, changed = 0; + for (j=0; jn_sample ) return rec; + + int ngts = bcf_get_genotypes(in_hdr, rec, >s, &mgts); + ngts /= rec->n_sample; + int i, j, changed = 0; + + // Calculating allele frequency for each allele and determining major allele + // only do this if use_major is true + int an = 0, maxAC = -1, majorAllele = -1; + if ( new_mask & GT_MAJOR ) + { + hts_expand(int,rec->n_allele,marr,arr); + int ret = bcf_calc_ac(in_hdr,rec,arr,BCF_UN_FMT); + if ( ret<= 0 ) + error("Could not calculate allele count at %s:%d\n", bcf_seqname(in_hdr,rec),rec->pos+1); + + for(i=0; i < rec->n_allele; ++i) + { + an += arr[i]; + if (arr[i] > maxAC) + { + maxAC = arr[i]; + majorAllele = i; + } + } + + // replacing new_gt by major allele + new_gt = new_mask & GT_PHASED ? bcf_gt_phased(majorAllele) : bcf_gt_unphased(majorAllele); + } + + // replace gts + if ( tgt_mask>_QUERY ) + { + int pass_site = filter_test(filter,rec,&smpl_pass); + if ( (pass_site && filter_logic==FLT_EXCLUDE) || (!pass_site && filter_logic==FLT_INCLUDE) ) return rec; + for (i=0; in_sample; i++) + { + if ( smpl_pass ) + { + if ( !smpl_pass[i] && filter_logic==FLT_INCLUDE ) continue; + if ( smpl_pass[i] && filter_logic==FLT_EXCLUDE ) continue; + } + + if ( new_mask>_UNPHASED ) + changed += unphase_gt(gts + i*ngts, ngts); + else + changed += set_gt(gts + i*ngts, ngts, new_gt); + } + } + else + { + for (i=0; in_sample; i++) + { + int ploidy = 0, nmiss = 0; + int32_t *ptr = gts + i*ngts; + for (j=0; jn_sample); + return rec; +} + +void destroy(void) +{ + if ( filter ) filter_destroy(filter); + free(arr); + fprintf(stderr,"Filled %"PRId64" alleles\n", nchanged); + free(gts); +} + + diff --git a/plugins/setGT.mk b/plugins/setGT.mk new file mode 100644 index 0000000..bb61b20 --- /dev/null +++ b/plugins/setGT.mk @@ -0,0 +1,2 @@ +plugins/setGT.so: plugins/setGT.c version.h version.c filter.h filter.c + $(CC) $(PLUGIN_FLAGS) $(CFLAGS) $(EXTRA_CPPFLAGS) $(CPPFLAGS) $(LDFLAGS) -o $@ filter.c version.c $< $(LIBS) diff --git a/plugins/tag2tag.c b/plugins/tag2tag.c new file mode 100644 index 0000000..54ac8d0 --- /dev/null +++ b/plugins/tag2tag.c @@ -0,0 +1,254 @@ +/* plugins/tag2tag.c -- convert between similar tags + + Copyright (C) 2014-2016 Genome Research Ltd. + + Author: Petr Danecek + +Permission is hereby granted, free of charge, to any person obtaining a copy +of this software and associated documentation files (the "Software"), to deal +in the Software without restriction, including without limitation the rights +to use, copy, modify, merge, publish, distribute, sublicense, and/or sell +copies of the Software, and to permit persons to whom the Software is +furnished to do so, subject to the following conditions: + +The above copyright notice and this permission notice shall be included in +all copies or substantial portions of the Software. + +THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL +THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER +LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING +FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER +DEALINGS IN THE SOFTWARE. */ + +#include +#include +#include +#include +#include +#include +#include "bcftools.h" + + +#define GP_TO_GL 1 +#define GL_TO_PL 2 +#define GP_TO_GT 3 +#define PL_TO_GL 4 + +static int mode = 0, drop_source_tag = 0; +static bcf_hdr_t *in_hdr, *out_hdr; +static float *farr = NULL, thresh = 0.1; +static int32_t *iarr = NULL; +static int mfarr = 0, miarr = 0; + +const char *about(void) +{ + return "Convert between similar tags, such as GL, PL and GP.\n"; +} + +const char *usage(void) +{ + return + "\n" + "About: Convert between similar tags, such as GL, PL and GP.\n" + "Usage: bcftools +tag2tag [General Options] -- [Plugin Options]\n" + "Options:\n" + " run \"bcftools plugin\" for a list of common options\n" + "\n" + "Plugin options:\n" + " --gp-to-gl convert FORMAT/GP to FORMAT/GL\n" + " --gp-to-gt convert FORMAT/GP to FORMAT/GT by taking argmax of GP\n" + " --gl-to-pl convert FORMAT/GL to FORMAT/PL\n" + " --pl-to-gl convert FORMAT/PL to FORMAT/GL\n" + " -r, --replace drop the source tag\n" + " -t, --threshold threshold for GP to GT hard-call [0.1]\n" + "\n" + "Example:\n" + " bcftools +tag2tag in.vcf -- -r --gp-to-gl\n" + "\n"; +} + + +static void init_header(bcf_hdr_t *hdr, const char *ori, int ori_type, const char *new_hdr_line) +{ + if ( ori ) + bcf_hdr_remove(hdr,ori_type,ori); + + bcf_hdr_append(hdr, new_hdr_line); +} + +int init(int argc, char **argv, bcf_hdr_t *in, bcf_hdr_t *out) +{ + static struct option loptions[] = + { + {"replace",no_argument,NULL,'r'}, + {"gp-to-gl",no_argument,NULL,1}, + {"gl-to-pl",no_argument,NULL,2}, + {"gp-to-gt",no_argument,NULL,3}, + {"pl-to-gl",no_argument,NULL,4}, + {"threshold",required_argument,NULL,'t'}, + {NULL,0,NULL,0} + }; + int c; + char *src_tag = "GP"; + while ((c = getopt_long(argc, argv, "?hrt:",loptions,NULL)) >= 0) + { + switch (c) + { + case 1 : src_tag = "GP"; mode = GP_TO_GL; break; + case 2 : src_tag = "GL"; mode = GL_TO_PL; break; + case 3 : src_tag = "GP"; mode = GP_TO_GT; break; + case 4 : src_tag = "PL"; mode = PL_TO_GL; break; + case 'r': drop_source_tag = 1; break; + case 't': thresh = atof(optarg); break; + case 'h': + case '?': + default: error("%s", usage()); break; + } + } + if ( !mode ) mode = GP_TO_GL; + + in_hdr = in; + out_hdr = out; + + if ( mode==GP_TO_GL ) + init_header(out_hdr,drop_source_tag?"GP":NULL,BCF_HL_FMT,"##FORMAT="); + else if ( mode==GL_TO_PL ) + init_header(out_hdr,drop_source_tag?"GL":NULL,BCF_HL_FMT,"##FORMAT="); + else if ( mode==PL_TO_GL ) + init_header(out_hdr,drop_source_tag?"PL":NULL,BCF_HL_FMT,"##FORMAT="); + else if ( mode==GP_TO_GT ) { + if (thresh<0||thresh>1) error("--threshold must be in the range [0,1]: %f\n", thresh); + init_header(out_hdr,drop_source_tag?"GP":NULL,BCF_HL_FMT,"##FORMAT="); + } + + int tag_id; + if ( (tag_id=bcf_hdr_id2int(in_hdr,BCF_DT_ID,src_tag))<0 || !bcf_hdr_idinfo_exists(in_hdr,BCF_HL_FMT,tag_id) ) + error("The source tag does not exist: %s\n", src_tag); + + return 0; +} + +bcf1_t *process(bcf1_t *rec) +{ + int i, n; + if ( mode==GP_TO_GL ) + { + n = bcf_get_format_float(in_hdr,rec,"GP",&farr,&mfarr); + if ( n<=0 ) return rec; + for (i=0; in_allele; + int nsmpl = bcf_hdr_nsamples(in_hdr); + hts_expand(int32_t,nsmpl*2,miarr,iarr); + + n = bcf_get_format_float(in_hdr,rec,"GP",&farr,&mfarr); + if ( n<=0 ) return rec; + + n /= nsmpl; + for (i=0; i ptr[jmax] ) jmax = j; + } + + // haploid genotype + if ( j==nals ) + { + iarr[2*i] = ptr[jmax] < 1-thresh ? bcf_gt_missing : bcf_gt_unphased(jmax); + iarr[2*i+1] = bcf_int32_vector_end; + continue; + } + + if ( j!=nals*(nals+1)/2 ) + error("Wrong number of GP values for diploid genotype at %s:%d, expected %d, found %d\n", + bcf_seqname(in_hdr,rec),rec->pos+1, nals*(nals+1)/2,j); + + if (ptr[jmax] < 1-thresh) + { + iarr[2*i] = iarr[2*i+1] = bcf_gt_missing; + continue; + } + + // most common case: RR + if ( jmax==0 ) + { + iarr[2*i] = iarr[2*i+1] = bcf_gt_unphased(0); + continue; + } + + int a,b; + bcf_gt2alleles(jmax,&a,&b); + iarr[2*i] = bcf_gt_unphased(a); + iarr[2*i+1] = bcf_gt_unphased(b); + } + bcf_update_genotypes(out_hdr,rec,iarr,nsmpl*2); + if ( drop_source_tag ) + bcf_update_format_float(out_hdr,rec,"GP",NULL,0); + } + return rec; +} + +void destroy(void) +{ + free(farr); + free(iarr); +} + + diff --git a/plugins/trio-switch-rate.c b/plugins/trio-switch-rate.c new file mode 100644 index 0000000..34f840d --- /dev/null +++ b/plugins/trio-switch-rate.c @@ -0,0 +1,273 @@ +/* The MIT License + + Copyright (c) 2016 Genome Research Ltd. + + Author: Petr Danecek + + Permission is hereby granted, free of charge, to any person obtaining a copy + of this software and associated documentation files (the "Software"), to deal + in the Software without restriction, including without limitation the rights + to use, copy, modify, merge, publish, distribute, sublicense, and/or sell + copies of the Software, and to permit persons to whom the Software is + furnished to do so, subject to the following conditions: + + The above copyright notice and this permission notice shall be included in + all copies or substantial portions of the Software. + + THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR + IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, + FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE + AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER + LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, + OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN + THE SOFTWARE. + + */ + +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include "bcftools.h" + +typedef struct +{ + int father, mother, child; // VCF sample index + int prev, ipop; + uint32_t err, nswitch, ntest; +} +trio_t; + +typedef struct +{ + char *name; + uint32_t err, nswitch, ntest, ntrio; + float pswitch; +} +pop_t; + +typedef struct +{ + int argc; + char **argv; + bcf_hdr_t *hdr; + trio_t *trio; + int ntrio, mtrio; + int32_t *gt_arr; + int npop; + pop_t *pop; + int mgt_arr, prev_rid; +} +args_t; + +args_t args; + +const char *about(void) +{ + return "Calculate phase switch rate in trio samples, children samples must have phased GTs.\n"; +} + +const char *usage(void) +{ + return + "\n" + "About: Calculate phase switch rate in trio children.\n" + "Usage: bcftools +trio-swich-rate [General Options] -- [Plugin Options]\n" + "Options:\n" + " run \"bcftools plugin\" for a list of common options\n" + "\n" + "Plugin options:\n" + " -p, --ped PED file with optional 7th column to group\n" + " results by population\n" + "\n" + "Example:\n" + " bcftools +trio-switch-rate file.bcf -- -p file.ped\n" + "\n"; +} + +void parse_ped(args_t *args, char *fname) +{ + htsFile *fp = hts_open(fname, "r"); + if ( !fp ) error("Could not read: %s\n", fname); + + kstring_t str = {0,0,0}; + if ( hts_getline(fp, KS_SEP_LINE, &str) <= 0 ) error("Empty file: %s\n", fname); + + void *pop2i = khash_str2int_init(); + + int moff = 0, *off = NULL; + do + { + // familyID sampleID paternalID maternalID sex phenotype population relationship siblings secondOrder thirdOrder children comment + // BB03 HG01884 HG01885 HG01956 2 0 ACB child 0 0 0 0 + int ncols = ksplit_core(str.s,0,&moff,&off); + if ( ncols<4 ) error("Could not parse the ped file: %s\n", str.s); + + int father = bcf_hdr_id2int(args->hdr,BCF_DT_SAMPLE,&str.s[off[2]]); + if ( father<0 ) continue; + int mother = bcf_hdr_id2int(args->hdr,BCF_DT_SAMPLE,&str.s[off[3]]); + if ( mother<0 ) continue; + int child = bcf_hdr_id2int(args->hdr,BCF_DT_SAMPLE,&str.s[off[1]]); + if ( child<0 ) continue; + + args->ntrio++; + hts_expand0(trio_t,args->ntrio,args->mtrio,args->trio); + trio_t *trio = &args->trio[args->ntrio-1]; + trio->father = father; + trio->mother = mother; + trio->child = child; + + if (ncols>6) { + char *pop_name = &str.s[off[6]]; + if ( !khash_str2int_has_key(pop2i,pop_name) ) + { + pop_name = strdup(&str.s[off[6]]); + khash_str2int_set(pop2i,pop_name,args->npop); + args->npop++; + args->pop = (pop_t*) realloc(args->pop,args->npop*sizeof(*args->pop)); + memset(args->pop+args->npop-1,0,sizeof(*args->pop)); + args->pop[args->npop-1].name = pop_name; + } + khash_str2int_get(pop2i,pop_name,&trio->ipop); + args->pop[trio->ipop].ntrio++; + } + } while ( hts_getline(fp, KS_SEP_LINE, &str)>=0 ); + + khash_str2int_destroy(pop2i); + free(str.s); + free(off); + hts_close(fp); +} + +int init(int argc, char **argv, bcf_hdr_t *in, bcf_hdr_t *out) +{ + memset(&args,0,sizeof(args_t)); + args.argc = argc; args.argv = argv; + args.prev_rid = -1; + args.hdr = in; + char *ped_fname = NULL; + static struct option loptions[] = + { + {"ped",required_argument,NULL,'p'}, + {0,0,0,0} + }; + int c; + while ((c = getopt_long(argc, argv, "?hp:",loptions,NULL)) >= 0) + { + switch (c) + { + case 'p': ped_fname = optarg; break; + case 'h': + case '?': + default: error("%s", usage()); break; + } + } + if ( !ped_fname ) error("Expected the -p option\n"); + parse_ped(&args, ped_fname); + return 1; +} + +typedef struct +{ + int a, b, phased; +} +gt_t; + +int parse_genotype(gt_t *gt, int32_t *ptr); + +inline int parse_genotype(gt_t *gt, int32_t *ptr) +{ + if ( ptr[0]==bcf_gt_missing ) return 0; + if ( ptr[1]==bcf_gt_missing ) return 0; + if ( ptr[1]==bcf_int32_vector_end ) return 0; + gt->phased = bcf_gt_is_phased(ptr[1]) ? 1 : 0; + gt->a = bcf_gt_allele(ptr[0]); if ( gt->a > 1 ) return 0; // consider only the first two alleles at biallelic sites + gt->b = bcf_gt_allele(ptr[1]); if ( gt->b > 1 ) return 0; + return 1; +} + +bcf1_t *process(bcf1_t *rec) +{ + int ngt = bcf_get_genotypes(args.hdr, rec, &args.gt_arr, &args.mgt_arr); + if ( ngt<0 ) return NULL; + ngt /= bcf_hdr_nsamples(args.hdr); + if ( ngt!=2 ) return NULL; + + int i; + if ( rec->rid!=args.prev_rid ) + { + args.prev_rid = rec->rid; + for (i=0; ichild) ) continue; + if ( !child.phased ) continue; + if ( child.a+child.b != 1 ) continue; // child is not a het + + if ( !parse_genotype(&father, args.gt_arr + ngt*trio->father) ) continue; + if ( !parse_genotype(&mother, args.gt_arr + ngt*trio->mother) ) continue; + if ( father.a+father.b == 1 && mother.a+mother.b == 1 ) continue; // both parents are hets + if ( father.a+father.b == mother.a+mother.b ) { trio->err++; continue; } // mendelian error + + int test_phase = 0; + if ( father.a==father.b ) test_phase = 1 + (child.a==father.a); + else if ( mother.a==mother.b ) test_phase = 1 + (child.b==mother.a); + if ( trio->prev > 0 ) + { + if ( trio->prev!=test_phase ) trio->nswitch++; + } + trio->ntest++; + trio->prev = test_phase; + } + return NULL; +} + +void destroy(void) +{ + int i; + printf("# This file was produced by: bcftools +trio-switch-rate(%s+htslib-%s)\n", bcftools_version(),hts_version()); + printf("# The command line was:\tbcftools +trio-switch-rate %s", args.argv[0]); + for (i=1; ifather), + bcf_hdr_int2id(args.hdr,BCF_DT_SAMPLE,trio->mother), + bcf_hdr_int2id(args.hdr,BCF_DT_SAMPLE,trio->child), + trio->ntest, trio->err, trio->nswitch, trio->ntest ? trio->nswitch*100./trio->ntest : 0 + ); + if (args.npop) { + pop_t *pop = &args.pop[trio->ipop]; + pop->err += trio->err; + pop->nswitch += trio->nswitch; + pop->ntest += trio->ntest; + pop->pswitch += trio->ntest ? trio->nswitch*100./trio->ntest : 0; + } + } + printf("# POP\tpopulation or other grouping defined by an optional 7-th column of the PED file\n"); + printf("# POP\t[2]Name\t[3]Number of trios\t[4]avgTested\t[5]avgMendelian Errors\t[6]avgSwitch\t[7]avgSwitch (%%)\n"); + for (i=0; iname,pop->ntrio, + (float)pop->ntest/pop->ntrio,(float)pop->err/pop->ntrio,(float)pop->nswitch/pop->ntrio, + pop->pswitch/pop->ntrio); + } + for (i=0; i + + Permission is hereby granted, free of charge, to any person obtaining a copy + of this software and associated documentation files (the "Software"), to deal + in the Software without restriction, including without limitation the rights + to use, copy, modify, merge, publish, distribute, sublicense, and/or sell + copies of the Software, and to permit persons to whom the Software is + furnished to do so, subject to the following conditions: + + The above copyright notice and this permission notice shall be included in + all copies or substantial portions of the Software. + + THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR + IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, + FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE + AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER + LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, + OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN + THE SOFTWARE. + + */ + +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include "bcftools.h" +#include "peakfit.h" + +typedef struct +{ + int nvals; // all values, including RR,AA peaks + double *xvals; // pointer to args_t.xvals + double *yvals; + int copy_number; // heuristics to skip futile CN1 fits when no het peak is detected + int irr, ira, iaa; // chop off RR and AA peaks + char *chr; +} +dist_t; + +typedef struct +{ + int ndist, nbins, ra_rr_scaling, smooth; + double *xvals; + dist_t *dist; + char **argv, *output_dir; + double fit_th, peak_symmetry, cn_penalty, min_peak_size, min_fraction; + int argc, plot, verbose, regions_is_file, targets_is_file, include_aa, force_cn; + char *dat_fname, *fname, *regions_list, *targets_list, *sample; + FILE *dat_fp; +} +args_t; + +FILE *open_file(char **fname, const char *mode, const char *fmt, ...); + +static void init_dist(args_t *args, dist_t *dist, int verbose) +{ + // isolate RR and AA peaks and rescale so that they are comparable to hets + int i, irr, iaa, n = dist->nvals; + + // smooth the distribution, this is just to find the peaks + double *tmp = (double*) malloc(sizeof(double)*n); + int win = args->smooth ? fabs(args->smooth)*2 + 1 : 7; // must be an odd number + int hwin = win/2; + double avg = tmp[0] = dist->yvals[0]; + for (i=1; iyvals[2*i-1]; + tmp[i] = avg/(2*i+1); + } + avg = 0; + for (i=0; iyvals[i]; + if ( i>=win-1 ) + { + tmp[i-hwin] = avg/win; + avg -= dist->yvals[i-win+1]; + } + } + for (i=n-hwin; iyvals[i-hwin]; + hwin--; + tmp[i] = avg/(2*hwin+1); + avg -= dist->yvals[i-hwin]; + } + + // find the extremes; first a simple approach: find a gap + for (irr=0,i=0; i=n/2; i--) if ( tmp[i] < tmp[iaa] ) iaa = i; + irr += win*0.5; + iaa += win*0.5; + if ( iaa>=n ) iaa = n-1; + if ( irr>=iaa ) error("FIXME: oops, dist normalization failed for %s: %d vs %d\n", dist->chr,irr,iaa); // we may need to be smarter + if ( args->smooth>0 ) for (i=0; iyvals[i] = tmp[i]; + free(tmp); + + // clean the data: the AA peak is occasionally not centered at 1.0 but is closer to the center, chop off + int imax_aa = iaa; + for (i=iaa; iyvals[imax_aa] < dist->yvals[i] ) imax_aa = i; + dist->nvals = imax_aa+1; + if ( iaa>=dist->nvals ) iaa = dist->nvals-1; + + // find the maximum and scale the peaks (first draft: no attempt to join the segments smootly) + double max_rr = 0, max_aa = 0, max_ra = 0, srr = 0, saa = 0, sra = 0; + for (i=0; iyvals[i]; + if ( max_rr < dist->yvals[i] ) max_rr = dist->yvals[i]; + } + for (i=irr; i<=iaa; i++) + { + sra += dist->yvals[i]; + if ( max_ra < dist->yvals[i] ) max_ra = dist->yvals[i]; + } + for (i=iaa+1; iyvals[i]; + if ( max_aa < dist->yvals[i] ) max_aa = dist->yvals[i]; + } + + + // Does the het peak exist at all? Usually the numbers are as follows: + // 1: cn=0 ra/rr=0.205730 aa/ra=0.674922 nra=7066 + // 20: cn=0 ra/rr=0.258019 aa/ra=0.548929 nra=2381 + // X: cn=0 ra/rr=0.005976 aa/ra=44.116667 nra=60 + // Y: cn=0 ra/rr=0.008316 aa/ra=7.250000 nra=12 + // MT: cn=0 ra/rr=0.013699 aa/ra=0.666667 nra=3 + + if ( !args->ra_rr_scaling ) max_ra = max_aa = max_rr; + if ( !sra || (sra/srr<0.1 && saa/sra>1.0) ) // too few hets, CN1 + { + max_ra = max_aa; + dist->copy_number = 1; + } + else if ( sra/srr<0.1 || saa/sra>1.0 ) + { + max_ra = max_aa; + dist->copy_number = -1; // unknown copy number + } + if ( max_rr ) for (i=0; iyvals[i] /= max_rr; + if ( max_ra ) for (i=irr; i<=iaa; i++) dist->yvals[i] /= max_ra; + if ( max_aa ) for (i=iaa+1; iyvals[i] /= max_aa; + + dist->irr = irr; + dist->iaa = iaa; + dist->ira = n*0.5; + + if ( verbose ) + fprintf(stderr,"%s:\t irr,ira,iaa=%.2f,%.2f,%.2f \t cn=%2d \t ra/rr=%f \t aa/ra=%f \t nra=%d\n", + dist->chr, dist->xvals[irr],dist->xvals[dist->ira],dist->xvals[iaa], + dist->copy_number,sra/srr,saa/sra, (int)sra); +} + +static void init_data(args_t *args) +{ + bcf_srs_t *files = bcf_sr_init(); + if ( args->regions_list ) + { + if ( bcf_sr_set_regions(files, args->regions_list, args->regions_is_file)<0 ) + error("Failed to read the regions: %s\n", args->regions_list); + } + if ( args->targets_list ) + { + if ( bcf_sr_set_targets(files, args->targets_list, args->targets_is_file, 0)<0 ) + error("Failed to read the targets: %s\n", args->targets_list); + } + if ( !bcf_sr_add_reader(files, args->fname) ) error("Failed to open %s: %s\n", args->fname,bcf_sr_strerror(files->errnum)); + bcf_hdr_t *hdr = files->readers[0].header; + if ( !args->sample ) + { + if ( bcf_hdr_nsamples(hdr)>1 ) error("Missing the option -s, --sample\n"); + args->sample = hdr->samples[0]; + } + else if ( bcf_hdr_id2int(hdr,BCF_DT_SAMPLE,args->sample)<0 ) error("No such sample: %s\n", args->sample); + int ret = bcf_hdr_set_samples(hdr, args->sample, 0); + if ( ret<0 ) error("Error setting the sample: %s\n", args->sample); + + if ( !bcf_hdr_idinfo_exists(hdr,BCF_HL_FMT,bcf_hdr_id2int(hdr,BCF_DT_ID,"BAF")) ) + error("The tag FORMAT/BAF is not present in the VCF: %s\n", args->fname); + + int i; + args->xvals = (double*) calloc(args->nbins,sizeof(double)); + for (i=0; inbins; i++) args->xvals[i] = 1.0*i/(args->nbins-1); + + // collect BAF distributions for all chromosomes + int idist = -1, nbaf = 0, nprocessed = 0, ntotal = 0, prev_chr = -1; + float *baf = NULL; + while ( bcf_sr_next_line(files) ) + { + ntotal++; + + bcf1_t *line = bcf_sr_get_line(files,0); + if ( bcf_get_format_float(hdr,line,"BAF",&baf,&nbaf) != 1 ) continue; + if ( bcf_float_is_missing(baf[0]) ) continue; + + nprocessed++; + + if ( prev_chr==-1 || prev_chr!=line->rid ) + { + // new chromosome + idist = args->ndist++; + args->dist = (dist_t*) realloc(args->dist, sizeof(dist_t)*args->ndist); + memset(&args->dist[idist],0,sizeof(dist_t)); + args->dist[idist].chr = strdup(bcf_seqname(hdr,line)); + args->dist[idist].yvals = (double*) calloc(args->nbins,sizeof(double)); + args->dist[idist].xvals = args->xvals; + args->dist[idist].nvals = args->nbins; + prev_chr = line->rid; + } + int bin = baf[0]*(args->nbins-1); + args->dist[idist].yvals[bin]++; // the distribution + } + free(baf); + bcf_sr_destroy(files); + + for (idist=0; idistndist; idist++) + { + #if 0 + int j; + for (j=0; jnbins; j++) + { + double x = args->dist[idist].xvals[j]; + args->dist[idist].yvals[j] = exp(-(x-0.5)*(x-0.5)/1e-3); + } + #endif + init_dist(args, &args->dist[idist],args->verbose); + } + + args->dat_fp = open_file(&args->dat_fname,"w","%s/dist.dat", args->output_dir); + fprintf(args->dat_fp, "# This file was produced by: bcftools polysomy(%s+htslib-%s), the command line was:\n", bcftools_version(),hts_version()); + fprintf(args->dat_fp, "# \t bcftools %s ", args->argv[0]); + for (i=1; iargc; i++) + fprintf(args->dat_fp, " %s",args->argv[i]); + fprintf(args->dat_fp,"\n#\n"); + fprintf(args->dat_fp,"# DIST\t[2]Chrom\t[3]BAF\t[4]Normalized Count\n"); + fprintf(args->dat_fp,"# FIT\t[2]Goodness of Fit\t[3]iFrom\t[4]iTo\t[5]The Fitted Function\n"); + fprintf(args->dat_fp,"# CN\t[2]Chrom\t[3]Estimated Copy Number\t[4]Absolute fit deviation\n"); + + char *fname = NULL; + FILE *fp = open_file(&fname,"w","%s/dist.py", args->output_dir); +//-------- matplotlib script -------------- + fprintf(fp, + "#!/usr/bin/env python\n" + "#\n" + "import matplotlib as mpl\n" + "mpl.use('Agg')\n" + "import matplotlib.pyplot as plt\n" + "import csv,sys,argparse\n" + "from math import exp\n" + "\n" + "outdir = '%s'\n" + "\n" + "def read_dat(dat,fit,cn):\n" + " csv.register_dialect('tab', delimiter='\t', quoting=csv.QUOTE_NONE)\n" + " with open(outdir+'/dist.dat', 'rb') as f:\n" + " reader = csv.reader(f, 'tab')\n" + " for row in reader:\n" + " if row[0][0]=='#': continue\n" + " type = row[0]\n" + " chr = row[1]\n" + " if type=='DIST':\n" + " if chr not in dat: dat[chr] = []\n" + " dat[chr].append(row)\n" + " elif type=='FIT':\n" + " if chr not in fit: fit[chr] = []\n" + " fit[chr].append(row)\n" + " elif type=='CN':\n" + " cn[chr] = row[2]\n" + "\n" + "def plot_dist(dat,fit,chr):\n" + " fig, ax = plt.subplots(1, 1, figsize=(7,5))\n" + " ax.plot([x[2] for x in dat[chr]],[x[3] for x in dat[chr]],'k-',label='Distribution')\n" + " if chr in fit:\n" + " for i in range(len(fit[chr])):\n" + " pfit = fit[chr][i]\n" + " exec('def xfit(x): return '+pfit[5])\n" + " istart = int(pfit[3])\n" + " iend = int(pfit[4])+1\n" + " vals = dat[chr][istart:iend]\n" + " args = {}\n" + " if i==0: args = {'label':'Target to Fit'}\n" + " ax.plot([x[2] for x in vals],[x[3] for x in vals],'r-',**args)\n" + " if i==0: args = {'label':'Best Fit'}\n" + " ax.plot([x[2] for x in vals],[xfit(float(x[2])) for x in vals],'g-',**args)\n" + " ax.set_title('BAF distribution, chr'+chr)\n" + " ax.set_xlabel('BAF')\n" + " ax.set_ylabel('Frequency')\n" + " ax.legend(loc='best',prop={'size':7},frameon=False)\n" + " plt.savefig(outdir+'/dist.chr'+chr+'.png')\n" + " plt.close()\n" + "\n" + "def plot_copy_number(cn):\n" + " fig, ax = plt.subplots(1, 1, figsize=(7,5))\n" + " xlabels = sorted(cn.keys())\n" + " xvals = range(len(xlabels))\n" + " yvals = [float(cn[x]) for x in xlabels]\n" + " ax.plot(xvals,yvals,'o',color='red')\n" + " for i in range(len(xvals)):\n" + " if yvals[i]==-1: ax.annotate('?', xy=(xvals[i],0.5),va='center',ha='center',color='red',fontweight='bold')\n" + " ax.tick_params(axis='both', which='major', labelsize=9)\n" + " ax.set_xticks(xvals)\n" + " ax.set_xticklabels(xlabels,rotation=45)\n" + " ax.set_xlim(-1,len(xlabels))\n" + " ax.set_ylim(0,5.0)\n" + " ax.set_yticks([1.0,2.0,3.0,4.0])\n" + " ax.set_xlabel('Chromosome')\n" + " ax.set_ylabel('Copy Number')\n" + " plt.savefig(outdir+'/copy-number.png')\n" + " plt.close()\n" + "\n" + "class myParser(argparse.ArgumentParser):\n" + " def error(self, message):\n" + " self.print_help()\n" + " sys.stderr.write('error: %%s\\n' %% message)\n" + " sys.exit(2)\n" + "\n" + "def main():\n" + " parser = myParser()\n" + " parser.add_argument('-a', '--all', action='store_true', help='Create all plots')\n" + " parser.add_argument('-c', '--copy-number', action='store_true', help='Create copy-number plot')\n" + " parser.add_argument('-d', '--distrib', metavar='CHR', help='Plot BAF distribution of a single chromosome')\n" + " args = parser.parse_args()\n" + " dat = {}; fit = {}; cn = {}\n" + " read_dat(dat,fit,cn)\n" + " if args.distrib!=None:\n" + " plot_dist(dat,fit,args.distrib)\n" + " if args.all:\n" + " for chr in dat: plot_dist(dat,fit,chr)\n" + " plot_copy_number(cn)\n" + " elif args.copy_number:\n" + " plot_copy_number(cn)\n" + " else:\n" + " for chr in dat: plot_dist(dat,fit,chr)\n" + "\n" + "if __name__ == '__main__':\n" + " main()\n", + args->output_dir); +//--------------------------------------- + chmod(fname, S_IWUSR|S_IRUSR|S_IRGRP|S_IROTH|S_IXUSR|S_IXGRP|S_IXOTH); + free(fname); + fclose(fp); +} + +static void destroy_data(args_t *args) +{ + int i; + for (i=0; indist; i++) + { + free(args->dist[i].chr); + free(args->dist[i].yvals); + } + free(args->dist); + free(args->xvals); + free(args->dat_fname); + fclose(args->dat_fp); +} + +static void save_dist(args_t *args, dist_t *dist) +{ + int i; + for (i=0; inbins; i++) + fprintf(args->dat_fp,"DIST\t%s\t%f\t%f\n",dist->chr,dist->xvals[i],dist->yvals[i]); +} +static void fit_curves(args_t *args) +{ + peakfit_t *pkf = peakfit_init(); + peakfit_verbose(pkf,args->verbose); + + int i, nmc = 50; + for (i=0; indist; i++) + { + dist_t *dist = &args->dist[i]; + save_dist(args, &args->dist[i]); + + if ( dist->copy_number!=0 ) + { + fprintf(args->dat_fp,"CN\t%s\t%.2f\n", dist->chr,(float)dist->copy_number); + continue; + } + + if ( args->verbose ) + fprintf(stderr,"%s:\n", dist->chr); + + int nrr_aa = dist->iaa - dist->irr + 1; + int nrr_ra = dist->ira - dist->irr + 1; + int naa_max = dist->nvals - dist->iaa; + double xrr = dist->xvals[dist->irr], *xrr_vals = &dist->xvals[dist->irr], *yrr_vals = &dist->yvals[dist->irr]; + double xaa = dist->xvals[dist->iaa], *xaa_vals = &dist->xvals[dist->iaa], *yaa_vals = &dist->yvals[dist->iaa]; + double xra = dist->xvals[dist->ira]; + double xmax = dist->xvals[dist->nvals-1]; + + + // CN2 + double cn2aa_fit = 0, cn2ra_fit, cn2_fit; + char *cn2aa_func = 0, *cn2ra_func; + double cn2aa_params[3] = {1,1,1} ,cn2ra_params[3]; + if ( args->include_aa ) + { + peakfit_reset(pkf); + peakfit_add_exp(pkf, 1.0,1.0,0.2, 5); + peakfit_set_mc(pkf, 0.01,0.3,2,nmc); + peakfit_set_mc(pkf, 0.05,1.0,0,nmc); + cn2aa_fit = peakfit_run(pkf, naa_max, xaa_vals, yaa_vals); + cn2aa_func = strdup(peakfit_sprint_func(pkf)); + peakfit_get_params(pkf,0,cn2aa_params,3); + } + peakfit_reset(pkf); + peakfit_add_bounded_gaussian(pkf, 1.0,0.5,0.03, 0.45,0.55, 7); + peakfit_set_mc(pkf, 0.01,0.3,2,nmc); + peakfit_set_mc(pkf, 0.05,1.0,0,nmc); + cn2ra_fit = peakfit_run(pkf, nrr_aa,xrr_vals,yrr_vals); + cn2ra_func = strdup(peakfit_sprint_func(pkf)); + cn2_fit = cn2ra_fit + cn2aa_fit; + peakfit_get_params(pkf,0,cn2ra_params,3); + + + // CN3: fit two peaks, then enforce the symmetry and fit again + double cn3rra_params[5], cn3raa_params[5], *cn3aa_params = cn2aa_params; + double cn3aa_fit = cn2aa_fit, cn3ra_fit; + char *cn3aa_func = cn2aa_func, *cn3ra_func; + double min_dx3 = 0.5 - 1./(args->min_fraction+2); + peakfit_reset(pkf); + peakfit_add_bounded_gaussian(pkf, 1.0,1/3.,0.03, xrr,xra-min_dx3, 7); + peakfit_set_mc(pkf, xrr,xra-min_dx3, 1,nmc); + peakfit_add_bounded_gaussian(pkf, 1.0,2/3.,0.03, xra+min_dx3,xaa, 7); + peakfit_set_mc(pkf, xra+min_dx3,xaa, 1,nmc); + peakfit_run(pkf, nrr_aa, xrr_vals, yrr_vals); + // force symmetry around x=0.5 + peakfit_get_params(pkf,0,cn3rra_params,5); + peakfit_get_params(pkf,1,cn3raa_params,5); + double cn3_dx = (0.5-cn3rra_params[1] + cn3raa_params[1]-0.5)*0.5; + if ( cn3_dx > 0.5/3 ) cn3_dx = 0.5/3; // CN3 peaks should not be separated by more than 1/3 + peakfit_reset(pkf); + peakfit_add_gaussian(pkf, cn3rra_params[0],0.5-cn3_dx,cn3rra_params[2], 5); + peakfit_add_gaussian(pkf, cn3raa_params[0],0.5+cn3_dx,cn3raa_params[2], 5); + cn3ra_fit = peakfit_run(pkf, nrr_aa, xrr_vals, yrr_vals); + cn3ra_func = strdup(peakfit_sprint_func(pkf)); + // compare peak sizes + peakfit_get_params(pkf,0,cn3rra_params,3); + peakfit_get_params(pkf,1,cn3raa_params,3); + double cn3rra_size = cn3rra_params[0]*cn3rra_params[0]; + double cn3raa_size = cn3raa_params[0]*cn3raa_params[0]; + double cn3_dy = cn3rra_size > cn3raa_size ? cn3raa_size/cn3rra_size : cn3rra_size/cn3raa_size; + double cn3_frac = (1 - 2*cn3rra_params[1]) / cn3rra_params[1]; + double cn3_fit = cn3ra_fit + cn3aa_fit; + // A very reasonable heuristics: check if the peak's width converged, exclude far too broad or far too narrow peaks + if ( cn3rra_params[2]>0.3 || cn3raa_params[2]>0.3 ) cn3_fit = HUGE_VAL; + if ( cn3rra_params[2]<1e-2 || cn3raa_params[2]<1e-2 ) cn3_fit = HUGE_VAL; + + + // CN4 (contaminations) + // - first fit only the [0,0.5] part of the data, then enforce the symmetry and fit again + // - min_frac=1 (resp. 0.5) is interpreted as 50:50% (rep. 75:25%) contamination + double cn4AAaa_params[3] = {1,1,1} ,cn4AAra_params[3] = {1,1,1}, cn4RAra_params[3], cn4RArr_params[5], cn4RAaa_params[5]; + double cn4aa_fit = 0, cn4ra_fit; + char *cn4aa_func = 0, *cn4ra_func; + double min_dx4 = 0.25*args->min_fraction; + if ( args->include_aa ) + { + peakfit_reset(pkf); + peakfit_add_exp(pkf, 0.5,1.0,0.2, 5); + peakfit_set_mc(pkf, 0.01,0.3,2,nmc); + peakfit_add_bounded_gaussian(pkf, 0.4,(xaa+xmax)*0.5,2e-2, xaa,xmax, 7); + peakfit_set_mc(pkf, xaa,xmax, 1,nmc); + cn4aa_fit = peakfit_run(pkf, naa_max, xaa_vals,yaa_vals); + cn4aa_func = strdup(peakfit_sprint_func(pkf)); + peakfit_get_params(pkf,0,cn4AAaa_params,3); + peakfit_get_params(pkf,1,cn4AAra_params,5); + } + peakfit_reset(pkf); + // first fit only the [0,0.5] part of the data + peakfit_add_gaussian(pkf, 1.0,0.5,0.03, 5); + peakfit_add_bounded_gaussian(pkf, 0.6,0.3,0.03, xrr,xra-min_dx4, 7); + peakfit_set_mc(pkf, xrr,xra-min_dx4,2,nmc); + peakfit_run(pkf, nrr_ra , xrr_vals, yrr_vals); + // now forcet symmetry around x=0.5 + peakfit_get_params(pkf,0,cn4RAra_params,3); + peakfit_get_params(pkf,1,cn4RArr_params,5); + double cn4_dx = 0.5-cn4RArr_params[1]; + if ( cn4_dx > 0.25 ) cn4_dx = 0.25; // CN4 peaks should not be separated by more than 0.5 + peakfit_reset(pkf); + peakfit_add_gaussian(pkf, cn4RAra_params[0],0.5,cn4RAra_params[2], 5); + peakfit_add_gaussian(pkf, cn4RArr_params[0],0.5-cn4_dx,cn4RArr_params[2], 5); + peakfit_add_gaussian(pkf, cn4RArr_params[0],0.5+cn4_dx,cn4RArr_params[2], 5); + peakfit_set_mc(pkf, 0.1,cn4RAra_params[0],0,nmc); + peakfit_set_mc(pkf, 0.01,0.1,2,nmc); + cn4ra_fit = peakfit_run(pkf, nrr_aa , xrr_vals, yrr_vals); + cn4ra_func = strdup(peakfit_sprint_func(pkf)); + peakfit_get_params(pkf,0,cn4RAra_params,3); + peakfit_get_params(pkf,1,cn4RArr_params,3); + peakfit_get_params(pkf,2,cn4RAaa_params,3); + double cn4RAra_size = cn4RAra_params[0]==0 ? HUGE_VAL : cn4RAra_params[0]*cn4RAra_params[0]; + double cn4RArr_size = cn4RArr_params[0]*cn4RArr_params[0]; + double cn4RAaa_size = cn4RAaa_params[0]*cn4RAaa_params[0]; + double cn4RArr_dy = cn4RArr_size < cn4RAra_size ? cn4RArr_size/cn4RAra_size : cn4RAra_size/cn4RArr_size; + double cn4RAaa_dy = cn4RAaa_size < cn4RAra_size ? cn4RAaa_size/cn4RAra_size : cn4RAra_size/cn4RAaa_size; + double cn4_dy = cn4RArr_dy < cn4RAaa_dy ? cn4RArr_dy/cn4RAaa_dy : cn4RAaa_dy/cn4RArr_dy; + double cn4_ymin = cn4RArr_size < cn4RAaa_size ? cn4RArr_size/cn4RAra_size : cn4RAaa_size/cn4RAra_size; + cn4_dx = (cn4RAaa_params[1]-0.5) - (0.5-cn4RArr_params[1]); + double cn4_frac = cn4RAaa_params[1] - cn4RArr_params[1]; + double cn4_fit = cn4ra_fit + cn4aa_fit; + // A very reasonable heuristics: check if the peak's width converged, exclude far too broad or far too narrow peaks + if ( cn4RAra_params[2]>0.3 || cn4RArr_params[2]>0.3 || cn4RAaa_params[2]>0.3 ) cn4_fit = HUGE_VAL; + if ( cn4RAra_params[2]<1e-2 || cn4RArr_params[2]<1e-2 || cn4RAaa_params[2]<1e-2 ) cn4_fit = HUGE_VAL; + + + // Choose the best match + char cn2_fail = '*', cn3_fail = '*', cn4_fail = '*'; + if ( cn2_fit > args->fit_th ) cn2_fail = 'f'; + + if ( cn3_fit > args->fit_th ) cn3_fail = 'f'; + else if ( cn3_dy < args->peak_symmetry ) cn3_fail = 'y'; // size difference is too big + + if ( cn4_fit > args->fit_th ) cn4_fail = 'f'; + else if ( cn4_ymin < args->min_peak_size ) cn4_fail = 'y'; // side peak is too small + else if ( cn4_dy < args->peak_symmetry ) cn4_fail = 'Y'; // size difference is too big + else if ( cn4_dx > 0.1 ) cn4_fail = 'x'; // side peaks placed assymetrically + + double cn = -1, fit = cn2_fit; + if ( cn2_fail == '*' ) { cn = 2; fit = cn2_fit; } + if ( cn3_fail == '*' ) + { + // Use cn_penalty as a tiebreaker. If set to 0.3, cn3_fit must be 30% smaller than cn2_fit. + if ( cn<0 || cn3_fit < (1-args->cn_penalty) * fit ) + { + cn = 2 + cn3_frac; + fit = cn3_fit; + if ( cn2_fail=='*' ) cn2_fail = 'p'; + } + else cn3_fail = 'p'; + } + if ( cn4_fail == '*' ) + { + if ( cn<0 || cn4_fit < (1-args->cn_penalty) * fit ) + { + cn = 3 + cn4_frac; + fit = cn4_fit; + if ( cn2_fail=='*' ) cn2_fail = 'p'; + if ( cn3_fail=='*' ) cn3_fail = 'p'; + } + else cn4_fail = 'p'; + } + + if ( args->verbose ) + { + fprintf(stderr,"\tcn2 %c fit=%e\n", cn2_fail, cn2_fit); + fprintf(stderr,"\t .. %e\n", cn2ra_fit); + fprintf(stderr,"\t RA: %f %f %f\n", cn2ra_params[0],cn2ra_params[1],cn2ra_params[2]); + fprintf(stderr,"\t .. %e\n", cn2aa_fit); + fprintf(stderr,"\t AA: %f %f %f\n", cn2aa_params[0],cn2aa_params[1],cn2aa_params[2]); + fprintf(stderr,"\t func:\n"); + fprintf(stderr,"\t %s\n", cn2ra_func); + fprintf(stderr,"\t %s\n", cn2aa_func); + fprintf(stderr,"\n"); + fprintf(stderr,"\tcn3 %c fit=%e frac=%f symmetry=%f\n", cn3_fail, cn3_fit, cn3_frac, cn3_dy); + fprintf(stderr,"\t .. %e\n", cn3ra_fit); + fprintf(stderr,"\t RRA: %f %f %f\n", cn3rra_params[0],cn3rra_params[1],cn3rra_params[2]); + fprintf(stderr,"\t RAA: %f %f %f\n", cn3raa_params[0],cn3raa_params[1],cn3raa_params[2]); + fprintf(stderr,"\t .. %e\n", cn3aa_fit); + fprintf(stderr,"\t AAA: %f %f %f\n", cn3aa_params[0],cn3aa_params[1],cn3aa_params[2]); + fprintf(stderr,"\t func:\n"); + fprintf(stderr,"\t %s\n", cn3ra_func); + fprintf(stderr,"\t %s\n", cn3aa_func); + fprintf(stderr,"\n"); + fprintf(stderr,"\tcn4 %c fit=%e frac=%f symmetry=%f ymin=%f\n", cn4_fail, cn4_fit, cn4_frac, cn4_dy, cn4_ymin); + fprintf(stderr,"\t .. %e\n", cn4ra_fit); + fprintf(stderr,"\t RArr: %f %f %f\n", cn4RArr_params[0],cn4RArr_params[1],cn4RArr_params[2]); + fprintf(stderr,"\t RAra: %f %f %f\n", cn4RAra_params[0],cn4RAra_params[1],cn4RAra_params[2]); + fprintf(stderr,"\t RAaa: %f %f %f\n", cn4RAaa_params[0],cn4RAaa_params[1],cn4RAaa_params[2]); + fprintf(stderr,"\t .. %e\n", cn4aa_fit); + fprintf(stderr,"\t AAaa: %f %f %f\n", cn4AAaa_params[0],cn4AAaa_params[1],cn4AAaa_params[2]); + fprintf(stderr,"\t func:\n"); + fprintf(stderr,"\t %s\n", cn4ra_func); + fprintf(stderr,"\t %s\n", cn4aa_func); + fprintf(stderr,"\n"); + } + + if ( args->force_cn==2 || cn2_fail == '*' ) + { + fprintf(args->dat_fp,"FIT\t%s\t%e\t%d\t%d\t%s\n", dist->chr,cn2ra_fit,dist->irr,dist->iaa,cn2ra_func); + if ( cn2aa_func ) fprintf(args->dat_fp,"FIT\t%s\t%e\t%d\t%d\t%s\n", dist->chr,cn2aa_fit,dist->iaa,dist->nvals-1,cn2aa_func); + } + if ( args->force_cn==3 || cn3_fail == '*' ) + { + fprintf(args->dat_fp,"FIT\t%s\t%e\t%d\t%d\t%s\n", dist->chr,cn3ra_fit,dist->irr,dist->iaa,cn3ra_func); + if ( cn3aa_func ) fprintf(args->dat_fp,"FIT\t%s\t%e\t%d\t%d\t%s\n", dist->chr,cn3aa_fit,dist->iaa,dist->nvals-1,cn3aa_func); + } + if ( args->force_cn==4 || cn4_fail == '*' ) + { + fprintf(args->dat_fp,"FIT\t%s\t%e\t%d\t%d\t%s\n", dist->chr,cn4ra_fit,dist->irr,dist->iaa,cn4ra_func); + if ( cn4aa_func ) fprintf(args->dat_fp,"FIT\t%s\t%e\t%d\t%d\t%s\n", dist->chr,cn4aa_fit,dist->iaa,dist->nvals-1,cn4aa_func); + } + fprintf(args->dat_fp,"CN\t%s\t%.2f\t%f\n", dist->chr, cn, fit); + + free(cn2aa_func); + free(cn2ra_func); + free(cn3ra_func); + free(cn4ra_func); + free(cn4aa_func); + } + + peakfit_destroy(pkf); +} + +static void usage(args_t *args) +{ + fprintf(stderr, "\n"); + fprintf(stderr, "About: Detect number of chromosomal copies from Illumina's B-allele frequency (BAF)\n"); + fprintf(stderr, "Usage: bcftools polysomy [OPTIONS] \n"); + fprintf(stderr, "\n"); + fprintf(stderr, "General options:\n"); + fprintf(stderr, " -o, --output-dir \n"); + fprintf(stderr, " -r, --regions restrict to comma-separated list of regions\n"); + fprintf(stderr, " -R, --regions-file restrict to regions listed in a file\n"); + fprintf(stderr, " -s, --sample sample to analyze\n"); + fprintf(stderr, " -t, --targets similar to -r but streams rather than index-jumps\n"); + fprintf(stderr, " -T, --targets-file similar to -R but streams rather than index-jumps\n"); + fprintf(stderr, " -v, --verbose \n"); + fprintf(stderr, "\n"); + fprintf(stderr, "Algorithm options:\n"); + fprintf(stderr, " -b, --peak-size minimum peak size (0-1, larger is stricter) [0.1]\n"); + fprintf(stderr, " -c, --cn-penalty penalty for increasing CN (0-1, larger is stricter) [0.7]\n"); + fprintf(stderr, " -f, --fit-th goodness of fit threshold (>0, smaller is stricter) [3.3]\n"); + fprintf(stderr, " -i, --include-aa include the AA peak in CN2 and CN3 evaluation\n"); + fprintf(stderr, " -m, --min-fraction minimum distinguishable fraction of aberrant cells [0.1]\n"); + fprintf(stderr, " -p, --peak-symmetry peak symmetry threshold (0-1, larger is stricter) [0.5]\n"); + fprintf(stderr, "\n"); + exit(1); +} + +int main_polysomy(int argc, char *argv[]) +{ + args_t *args = (args_t*) calloc(1,sizeof(args_t)); + args->argc = argc; args->argv = argv; + args->nbins = 150; + args->fit_th = 3.3; + args->cn_penalty = 0.7; + args->peak_symmetry = 0.5; + args->min_peak_size = 0.1; + args->ra_rr_scaling = 1; + args->min_fraction = 0.1; + args->smooth = -3; + + static struct option loptions[] = + { + {"ra-rr-scaling",0,0,1}, // hidden option + {"force-cn",1,0,2}, // hidden option + {"smooth",1,0,'S'}, // hidden option + {"nbins",1,0,'n'}, // hidden option + {"include-aa",0,0,'i'}, + {"peak-size",1,0,'b'}, + {"min-fraction",1,0,'m'}, + {"verbose",0,0,'v'}, + {"fit-th",1,0,'f'}, + {"cn-penalty",1,0,'c'}, + {"peak-symmetry",1,0,'p'}, + {"output-dir",1,0,'o'}, + {"sample",1,0,'s'}, + {"targets",1,0,'t'}, + {"targets-file",1,0,'T'}, + {"regions",1,0,'r'}, + {"regions-file",1,0,'R'}, + {0,0,0,0} + }; + char *tmp; + int c; + while ((c = getopt_long(argc, argv, "h?o:vt:T:r:R:s:f:p:c:im:b:n:S:",loptions,NULL)) >= 0) + { + switch (c) + { + case 1 : args->ra_rr_scaling = 0; break; + case 2 : args->force_cn = atoi(optarg); break; + case 'n': args->nbins = atoi(optarg); break; + case 'S': args->smooth = atoi(optarg); break; + case 'i': args->include_aa = 1; break; + case 'b': + args->min_peak_size = strtod(optarg,&tmp); + if ( *tmp ) error("Could not parse: -b %s\n", optarg); + if ( args->min_peak_size<0 || args->min_peak_size>1 ) error("Range error: -b %s\n", optarg); + break; + case 'm': + args->min_fraction = strtod(optarg,&tmp); + if ( *tmp ) error("Could not parse: -n %s\n", optarg); + if ( args->min_fraction<0 || args->min_fraction>1 ) error("Range error: -n %s\n", optarg); + break; + case 'f': + args->fit_th = strtod(optarg,&tmp); + if ( *tmp ) error("Could not parse: -f %s\n", optarg); + break; + case 'p': + args->peak_symmetry = strtod(optarg,&tmp); + if ( *tmp ) error("Could not parse: -p %s\n", optarg); + break; + case 'c': + args->cn_penalty = strtod(optarg,&tmp); + if ( *tmp ) error("Could not parse: -c %s\n", optarg); + break; + case 's': args->sample = optarg; break; + case 't': args->targets_list = optarg; break; + case 'T': args->targets_list = optarg; args->targets_is_file = 1; break; + case 'r': args->regions_list = optarg; break; + case 'R': args->regions_list = optarg; args->regions_is_file = 1; break; + case 'o': args->output_dir = optarg; break; + case 'v': args->verbose++; break; + default: usage(args); break; + } + } + if ( optind>=argc ) + { + if ( !isatty(fileno((FILE *)stdin)) ) args->fname = "-"; + } + else args->fname = argv[optind]; + if ( !args->fname ) usage(args); + if ( !args->output_dir ) error("Missing the -o option\n"); + + init_data(args); + fit_curves(args); + destroy_data(args); + free(args); + + return 0; +} + + diff --git a/prob1.c b/prob1.c new file mode 100644 index 0000000..954d43c --- /dev/null +++ b/prob1.c @@ -0,0 +1,533 @@ +/* prob1.c -- mathematical utility functions. + + Copyright (C) 2010, 2011 Broad Institute. + Copyright (C) 2012, 2013 Genome Research Ltd. + + Author: Heng Li + +Permission is hereby granted, free of charge, to any person obtaining a copy +of this software and associated documentation files (the "Software"), to deal +in the Software without restriction, including without limitation the rights +to use, copy, modify, merge, publish, distribute, sublicense, and/or sell +copies of the Software, and to permit persons to whom the Software is +furnished to do so, subject to the following conditions: + +The above copyright notice and this permission notice shall be included in +all copies or substantial portions of the Software. + +THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE +AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER +LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, +OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN +THE SOFTWARE. */ + +#include +#include +#include +#include +#include +#include +#include +#include +#include "prob1.h" + +// #include "kstring.h" +// #include "kseq.h" +// KSTREAM_INIT(gzFile, gzread, 16384) + +#define MC_MAX_EM_ITER 16 +#define MC_EM_EPS 1e-5 +#define MC_DEF_INDEL 0.15 + +gzFile bcf_p1_fp_lk; + +void bcf_p1_indel_prior(bcf_p1aux_t *ma, double x) +{ + int i; + for (i = 0; i < ma->M; ++i) + ma->phi_indel[i] = ma->phi[i] * x; + ma->phi_indel[ma->M] = 1. - ma->phi[ma->M] * x; +} + +static void init_prior(int type, double theta, int M, double *phi) +{ + int i; + if (type == MC_PTYPE_COND2) { + for (i = 0; i <= M; ++i) + phi[i] = 2. * (i + 1) / (M + 1) / (M + 2); + } else if (type == MC_PTYPE_FLAT) { + for (i = 0; i <= M; ++i) + phi[i] = 1. / (M + 1); + } else { + double sum; + for (i = 0, sum = 0.; i < M; ++i) + sum += (phi[i] = theta / (M - i)); + phi[M] = 1. - sum; + } +} + +void bcf_p1_init_prior(bcf_p1aux_t *ma, int type, double theta) +{ + init_prior(type, theta, ma->M, ma->phi); + bcf_p1_indel_prior(ma, MC_DEF_INDEL); +} + +void bcf_p1_init_subprior(bcf_p1aux_t *ma, int type, double theta) +{ + if (ma->n1 <= 0 || ma->n1 >= ma->M) return; + init_prior(type, theta, 2*ma->n1, ma->phi1); + init_prior(type, theta, 2*(ma->n - ma->n1), ma->phi2); +} + + +/* Initialise a bcf_p1aux_t */ +bcf_p1aux_t *bcf_p1_init(int n_smpl, uint8_t *ploidy) +{ + bcf_p1aux_t *ma; + int i; + ma = (bcf_p1aux_t*) calloc(1, sizeof(bcf_p1aux_t)); + ma->n1 = -1; + ma->n = n_smpl; + ma->M = 2 * n_smpl; + if (ploidy) { + ma->ploidy = (uint8_t*) malloc(n_smpl); + memcpy(ma->ploidy, ploidy, n_smpl); + for (i = 0, ma->M = 0; i < n_smpl; ++i) ma->M += ploidy[i]; + if (ma->M == 2 * n_smpl) { + free(ma->ploidy); + ma->ploidy = 0; + } + } + ma->q2p = (double*) calloc(256, sizeof(double)); + ma->pdg = (double*) calloc(3 * ma->n, sizeof(double)); + ma->phi = (double*) calloc(ma->M + 1, sizeof(double)); + ma->phi_indel = (double*) calloc(ma->M + 1, sizeof(double)); + ma->phi1 = (double*) calloc(ma->M + 1, sizeof(double)); + ma->phi2 = (double*) calloc(ma->M + 1, sizeof(double)); + ma->z = (double*) calloc(ma->M + 1, sizeof(double)); + ma->zswap = (double*) calloc(ma->M + 1, sizeof(double)); + ma->z1 = (double*) calloc(ma->M + 1, sizeof(double)); // actually we do not need this large + ma->z2 = (double*) calloc(ma->M + 1, sizeof(double)); + ma->afs = (double*) calloc(ma->M + 1, sizeof(double)); + ma->afs1 = (double*) calloc(ma->M + 1, sizeof(double)); + ma->lf = (double*) calloc(ma->M + 1, sizeof(double)); + for (i = 0; i < 256; ++i) + ma->q2p[i] = pow(10., -i / 10.); + for (i = 0; i <= ma->M; ++i) ma->lf[i] = lgamma(i + 1); + bcf_p1_init_prior(ma, MC_PTYPE_FULL, 1e-3); // the simplest prior + return ma; +} + +int bcf_p1_get_M(bcf_p1aux_t *b) { return b->M; } + +int bcf_p1_set_n1(bcf_p1aux_t *b, int n1) +{ + if (n1 == 0 || n1 >= b->n) return -1; + if (b->M != b->n * 2) { + fprintf(stderr, "[%s] unable to set `n1' when there are haploid samples.\n", __func__); + return -1; + } + b->n1 = n1; + return 0; +} + +void bcf_p1_destroy(bcf_p1aux_t *ma) +{ + if (ma) { + int k; + free(ma->lf); + if (ma->hg && ma->n1 > 0) { + for (k = 0; k <= 2*ma->n1; ++k) free(ma->hg[k]); + free(ma->hg); + } + free(ma->ploidy); free(ma->q2p); free(ma->pdg); + free(ma->phi); free(ma->phi_indel); free(ma->phi1); free(ma->phi2); + free(ma->z); free(ma->zswap); free(ma->z1); free(ma->z2); + free(ma->afs); free(ma->afs1); + free(ma); + } +} + +extern double kf_gammap(double s, double z); +int test16(bcf1_t *b, anno16_t *a); + +/* Calculate P(D|g) */ +static int cal_pdg(const bcf1_t *b, bcf_p1aux_t *ma) +{ + int i, j; + long p_a[16], *p=p_a, tmp; + if (b->n_allele > 16) + p = (long*) malloc(b->n_allele * sizeof(long)); + memset(p, 0, sizeof(long) * b->n_allele); + + // Set P(D|g) for each sample and sum phread likelihoods across all samples to create lk + for (j = 0; j < ma->n; ++j) { + // Fetch the PL array for the sample + const int *pi = ma->PL + j * ma->PL_len; + // Fetch the P(D|g) array for the sample + double *pdg = ma->pdg + j * 3; + pdg[0] = ma->q2p[pi[2]]; pdg[1] = ma->q2p[pi[1]]; pdg[2] = ma->q2p[pi[0]]; + for (i = 0; i < b->n_allele; ++i) + p[i] += (int)pi[(i+1)*(i+2)/2-1]; + } + for (i = 0; i < b->n_allele; ++i) p[i] = p[i]<<4 | i; + for (i = 1; i < b->n_allele; ++i) // insertion sort + for (j = i; j > 0 && p[j] < p[j-1]; --j) + tmp = p[j], p[j] = p[j-1], p[j-1] = tmp; + for (i = b->n_allele - 1; i >= 0; --i) + if ((p[i]&0xf) == 0) break; + if (p != p_a) + free(p); + return i; +} + + +/* f0 is freq of the ref allele */ +int bcf_p1_call_gt(const bcf_p1aux_t *ma, double f0, int k, int is_var) +{ + double sum, g[3]; + double max, f3[3], *pdg = ma->pdg + k * 3; + int q, i, max_i, ploidy; + /* determine ploidy */ + ploidy = ma->ploidy? ma->ploidy[k] : 2; + if (ploidy == 2) { + /* given allele frequency we can determine how many of each + * genotype we have by HWE p=1-q PP=p^2 PQ&QP=2*p*q QQ=q^2 */ + f3[0] = (1.-f0)*(1.-f0); f3[1] = 2.*f0*(1.-f0); f3[2] = f0*f0; + } else { + f3[0] = 1. - f0; f3[1] = 0; f3[2] = f0; + } + for (i = 0, sum = 0.; i < 3; ++i) + sum += (g[i] = pdg[i] * f3[i]); + /* normalise g and then determine max */ + for (i = 0, max = -1., max_i = 0; i < 3; ++i) { + g[i] /= sum; + if (g[i] > max) max = g[i], max_i = i; + } + if ( !is_var ) { max_i = 2; max = g[2]; } // force 0/0 genotype if the site is non-variant + max = 1. - max; + if (max < 1e-308) max = 1e-308; + q = (int)(-4.343 * log(max) + .499); + if (q > 99) q = 99; + return q<<2|max_i; +} + +// If likelihoods fall below this they get squashed to 0 +#define TINY 1e-20 +static void mc_cal_y_core(bcf_p1aux_t *ma, int beg) +{ + double *z[2], *tmp, *pdg; + int _j, last_min, last_max; + assert(beg == 0 || ma->M == ma->n*2); + z[0] = ma->z; + z[1] = ma->zswap; + pdg = ma->pdg; + memset(z[0], 0, sizeof(double) * (ma->M + 1)); + memset(z[1], 0, sizeof(double) * (ma->M + 1)); + z[0][0] = 1.; + last_min = last_max = 0; + ma->t = 0.; + if (ma->M == ma->n * 2) { + int M = 0; + for (_j = beg; _j < ma->n; ++_j) { + int k, j = _j - beg, _min = last_min, _max = last_max, M0; + double p[3], sum; + M0 = M; M += 2; + // Fetch P(D|g) for this sample + pdg = ma->pdg + _j * 3; + p[0] = pdg[0]; p[1] = 2. * pdg[1]; p[2] = pdg[2]; + for (; _min < _max && z[0][_min] < TINY; ++_min) z[0][_min] = z[1][_min] = 0.; + for (; _max > _min && z[0][_max] < TINY; --_max) z[0][_max] = z[1][_max] = 0.; + _max += 2; + if (_min == 0) k = 0, z[1][k] = (M0-k+1) * (M0-k+2) * p[0] * z[0][k]; + if (_min <= 1) k = 1, z[1][k] = (M0-k+1) * (M0-k+2) * p[0] * z[0][k] + k*(M0-k+2) * p[1] * z[0][k-1]; + for (k = _min < 2? 2 : _min; k <= _max; ++k) + z[1][k] = (M0-k+1)*(M0-k+2) * p[0] * z[0][k] + k*(M0-k+2) * p[1] * z[0][k-1] + k*(k-1)* p[2] * z[0][k-2]; + for (k = _min, sum = 0.; k <= _max; ++k) sum += z[1][k]; + ma->t += log(sum / (M * (M - 1.))); + for (k = _min; k <= _max; ++k) z[1][k] /= sum; + if (_min >= 1) z[1][_min-1] = 0.; + if (_min >= 2) z[1][_min-2] = 0.; + // If we are not on the last sample + if (j < ma->n - 1) z[1][_max+1] = z[1][_max+2] = 0.; + if (_j == ma->n1 - 1) { // set pop1; ma->n1==-1 when unset + ma->t1 = ma->t; + memcpy(ma->z1, z[1], sizeof(double) * (ma->n1 * 2 + 1)); + } + tmp = z[0]; z[0] = z[1]; z[1] = tmp; + last_min = _min; last_max = _max; + } + //for (_j = 0; _j < last_min; ++_j) z[0][_j] = 0.; // TODO: are these necessary? + //for (_j = last_max + 1; _j < ma->M; ++_j) z[0][_j] = 0.; + } else { // this block is very similar to the block above; these two might be merged in future + int j, M = 0; + for (j = 0; j < ma->n; ++j) { + int k, M0, _min = last_min, _max = last_max; + double p[3], sum; + // Fetch P(D|g) for this sample + pdg = ma->pdg + j * 3; + for (; _min < _max && z[0][_min] < TINY; ++_min) z[0][_min] = z[1][_min] = 0.; + for (; _max > _min && z[0][_max] < TINY; --_max) z[0][_max] = z[1][_max] = 0.; + M0 = M; + M += ma->ploidy[j]; + if (ma->ploidy[j] == 1) { + p[0] = pdg[0]; p[1] = pdg[2]; + _max++; + if (_min == 0) k = 0, z[1][k] = (M0+1-k) * p[0] * z[0][k]; + for (k = _min < 1? 1 : _min; k <= _max; ++k) + z[1][k] = (M0+1-k) * p[0] * z[0][k] + k * p[1] * z[0][k-1]; + for (k = _min, sum = 0.; k <= _max; ++k) sum += z[1][k]; + ma->t += log(sum / M); + for (k = _min; k <= _max; ++k) z[1][k] /= sum; + if (_min >= 1) z[1][_min-1] = 0.; + // If we are not on the last sample + if (j < ma->n - 1) z[1][_max+1] = 0.; + } else if (ma->ploidy[j] == 2) { + p[0] = pdg[0]; p[1] = 2 * pdg[1]; p[2] = pdg[2]; + _max += 2; + if (_min == 0) k = 0, z[1][k] = (M0-k+1) * (M0-k+2) * p[0] * z[0][k]; + if (_min <= 1) k = 1, z[1][k] = (M0-k+1) * (M0-k+2) * p[0] * z[0][k] + k*(M0-k+2) * p[1] * z[0][k-1]; + for (k = _min < 2? 2 : _min; k <= _max; ++k) + z[1][k] = (M0-k+1)*(M0-k+2) * p[0] * z[0][k] + k*(M0-k+2) * p[1] * z[0][k-1] + k*(k-1)* p[2] * z[0][k-2]; + for (k = _min, sum = 0.; k <= _max; ++k) sum += z[1][k]; + ma->t += log(sum / (M * (M - 1.))); + for (k = _min; k <= _max; ++k) z[1][k] /= sum; + if (_min >= 1) z[1][_min-1] = 0.; + if (_min >= 2) z[1][_min-2] = 0.; + // If we are not on the last sample + if (j < ma->n - 1) z[1][_max+1] = z[1][_max+2] = 0.; + } + tmp = z[0]; z[0] = z[1]; z[1] = tmp; + last_min = _min; last_max = _max; + } + } + if (z[0] != ma->z) memcpy(ma->z, z[0], sizeof(double) * (ma->M + 1)); + if (bcf_p1_fp_lk) + gzwrite(bcf_p1_fp_lk, ma->z, sizeof(double) * (ma->M + 1)); +} + +static void mc_cal_y(bcf_p1aux_t *ma) +{ + if (ma->n1 > 0 && ma->n1 < ma->n && ma->M == ma->n * 2) { // NB: ma->n1 is ineffective when there are haploid samples + int k; + long double x; + memset(ma->z1, 0, sizeof(double) * (2 * ma->n1 + 1)); + memset(ma->z2, 0, sizeof(double) * (2 * (ma->n - ma->n1) + 1)); + ma->t1 = ma->t2 = 0.; + mc_cal_y_core(ma, ma->n1); + ma->t2 = ma->t; + memcpy(ma->z2, ma->z, sizeof(double) * (2 * (ma->n - ma->n1) + 1)); + mc_cal_y_core(ma, 0); + // rescale z + x = expl(ma->t - (ma->t1 + ma->t2)); + for (k = 0; k <= ma->M; ++k) ma->z[k] *= x; + } else mc_cal_y_core(ma, 0); +} + +#define CONTRAST_TINY 1e-30 + +extern double kf_gammaq(double s, double z); // incomplete gamma function for chi^2 test + +static inline double chi2_test(int a, int b, int c, int d) +{ + double x, z; + x = (double)(a+b) * (c+d) * (b+d) * (a+c); + if (x == 0.) return 1; + z = a * d - b * c; + return kf_gammaq(.5, .5 * z * z * (a+b+c+d) / x); +} + +// chi2=(a+b+c+d)(ad-bc)^2/[(a+b)(c+d)(a+c)(b+d)] +static inline double contrast2_aux(const bcf_p1aux_t *p1, double sum, int k1, int k2, double x[3]) +{ + double p = p1->phi[k1+k2] * p1->z1[k1] * p1->z2[k2] / sum * p1->hg[k1][k2]; + int n1 = p1->n1, n2 = p1->n - p1->n1; + if (p < CONTRAST_TINY) return -1; + if (.5*k1/n1 < .5*k2/n2) x[1] += p; + else if (.5*k1/n1 > .5*k2/n2) x[2] += p; + else x[0] += p; + return p * chi2_test(k1, k2, (n1<<1) - k1, (n2<<1) - k2); +} + +static double contrast2(bcf_p1aux_t *p1, double ret[3]) +{ + int k, k1, k2, k10, k20, n1, n2; + double sum; + // get n1 and n2 + n1 = p1->n1; n2 = p1->n - p1->n1; + if (n1 <= 0 || n2 <= 0) return 0.; + if (p1->hg == 0) { // initialize the hypergeometric distribution + /* NB: the hg matrix may take a lot of memory when there are many samples. There is a way + to avoid precomputing this matrix, but it is slower and quite intricate. The following + computation in this block can be accelerated with a similar strategy, but perhaps this + is not a serious concern for now. */ + double tmp = lgamma(2*(n1+n2)+1) - (lgamma(2*n1+1) + lgamma(2*n2+1)); + p1->hg = (double**) calloc(2*n1+1, sizeof(double*)); + for (k1 = 0; k1 <= 2*n1; ++k1) { + p1->hg[k1] = (double*)calloc(2*n2+1, sizeof(double)); + for (k2 = 0; k2 <= 2*n2; ++k2) + p1->hg[k1][k2] = exp(lgamma(k1+k2+1) + lgamma(p1->M-k1-k2+1) - (lgamma(k1+1) + lgamma(k2+1) + lgamma(2*n1-k1+1) + lgamma(2*n2-k2+1) + tmp)); + } + } + { // compute + long double suml = 0; + for (k = 0; k <= p1->M; ++k) suml += p1->phi[k] * p1->z[k]; + sum = suml; + } + { // get the max k1 and k2 + double max; + int max_k; + for (k = 0, max = 0, max_k = -1; k <= 2*n1; ++k) { + double x = p1->phi1[k] * p1->z1[k]; + if (x > max) max = x, max_k = k; + } + k10 = max_k; + for (k = 0, max = 0, max_k = -1; k <= 2*n2; ++k) { + double x = p1->phi2[k] * p1->z2[k]; + if (x > max) max = x, max_k = k; + } + k20 = max_k; + } + { // We can do the following with one nested loop, but that is an O(N^2) thing. The following code block is much faster for large N. + double x[3], y; + long double z = 0., L[2]; + x[0] = x[1] = x[2] = 0; L[0] = L[1] = 0; + for (k1 = k10; k1 >= 0; --k1) { + for (k2 = k20; k2 >= 0; --k2) { + if ((y = contrast2_aux(p1, sum, k1, k2, x)) < 0) break; + else z += y; + } + for (k2 = k20 + 1; k2 <= 2*n2; ++k2) { + if ((y = contrast2_aux(p1, sum, k1, k2, x)) < 0) break; + else z += y; + } + } + ret[0] = x[0]; ret[1] = x[1]; ret[2] = x[2]; + x[0] = x[1] = x[2] = 0; + for (k1 = k10 + 1; k1 <= 2*n1; ++k1) { + for (k2 = k20; k2 >= 0; --k2) { + if ((y = contrast2_aux(p1, sum, k1, k2, x)) < 0) break; + else z += y; + } + for (k2 = k20 + 1; k2 <= 2*n2; ++k2) { + if ((y = contrast2_aux(p1, sum, k1, k2, x)) < 0) break; + else z += y; + } + } + ret[0] += x[0]; ret[1] += x[1]; ret[2] += x[2]; + if (ret[0] + ret[1] + ret[2] < 0.95) { // in case of bad things happened + ret[0] = ret[1] = ret[2] = 0; L[0] = L[1] = 0; + for (k1 = 0, z = 0.; k1 <= 2*n1; ++k1) + for (k2 = 0; k2 <= 2*n2; ++k2) + if ((y = contrast2_aux(p1, sum, k1, k2, ret)) >= 0) z += y; + if (ret[0] + ret[1] + ret[2] < 0.95) // It seems that this may be caused by floating point errors. I do not really understand why... + z = 1.0, ret[0] = ret[1] = ret[2] = 1./3; + } + return (double)z; + } +} + +static double mc_cal_afs(bcf_p1aux_t *ma, double *p_ref_folded, double *p_var_folded) +{ + int k; + long double sum = 0., sum2; + double *phi = ma->is_indel? ma->phi_indel : ma->phi; + memset(ma->afs1, 0, sizeof(double) * (ma->M + 1)); + mc_cal_y(ma); + // compute AFS + // MP15: is this using equation 20 from doi:10.1093/bioinformatics/btr509? + for (k = 0, sum = 0.; k <= ma->M; ++k) + sum += (long double)phi[k] * ma->z[k]; + for (k = 0; k <= ma->M; ++k) { + ma->afs1[k] = phi[k] * ma->z[k] / sum; + if (isnan(ma->afs1[k]) || isinf(ma->afs1[k])) return -1.; + } + // compute folded variant probability + for (k = 0, sum = 0.; k <= ma->M; ++k) + sum += (long double)(phi[k] + phi[ma->M - k]) / 2. * ma->z[k]; + for (k = 1, sum2 = 0.; k < ma->M; ++k) + sum2 += (long double)(phi[k] + phi[ma->M - k]) / 2. * ma->z[k]; + *p_var_folded = sum2 / sum; + *p_ref_folded = (phi[k] + phi[ma->M - k]) / 2. * (ma->z[ma->M] + ma->z[0]) / sum; + // the expected frequency + for (k = 0, sum = 0.; k <= ma->M; ++k) { + ma->afs[k] += ma->afs1[k]; + sum += k * ma->afs1[k]; + } + return sum / ma->M; +} + +int bcf_p1_cal(call_t *call, bcf1_t *b, int do_contrast, bcf_p1aux_t *ma, bcf_p1rst_t *rst) +{ + int i, k; + long double sum = 0.; + ma->is_indel = bcf_is_snp(b) ? 0 : 1; + rst->perm_rank = -1; + + ma->PL = call->PLs; + ma->PL_len = call->nPLs / b->n_sample; + if (b->n_allele < 2) return -1; // FIXME: find a better solution + + rst->rank0 = cal_pdg(b, ma); + rst->f_exp = mc_cal_afs(ma, &rst->p_ref_folded, &rst->p_var_folded); + rst->p_ref = ma->afs1[ma->M]; + for (k = 0, sum = 0.; k < ma->M; ++k) + sum += ma->afs1[k]; + rst->p_var = (double)sum; + { // compute the allele count + double max = -1; + rst->ac = -1; + for (k = 0; k <= ma->M; ++k) + if (max < ma->z[k]) max = ma->z[k], rst->ac = k; + rst->ac = ma->M - rst->ac; + } + // calculate f_flat and f_em + for (k = 0, sum = 0.; k <= ma->M; ++k) + sum += (long double)ma->z[k]; + rst->f_flat = 0.; + for (k = 0; k <= ma->M; ++k) { + double p = ma->z[k] / sum; + rst->f_flat += k * p; + } + rst->f_flat /= ma->M; + { // estimate equal-tail credible interval (95% level) + int l, h; + double p; + for (i = 0, p = 0.; i <= ma->M; ++i) + if (p + ma->afs1[i] > 0.025) break; + else p += ma->afs1[i]; + l = i; + for (i = ma->M, p = 0.; i >= 0; --i) + if (p + ma->afs1[i] > 0.025) break; + else p += ma->afs1[i]; + h = i; + rst->cil = (double)(ma->M - h) / ma->M; rst->cih = (double)(ma->M - l) / ma->M; + } + if (ma->n1 > 0) { // compute LRT + double max0, max1, max2; + for (k = 0, max0 = -1; k <= ma->M; ++k) + if (max0 < ma->z[k]) max0 = ma->z[k]; + for (k = 0, max1 = -1; k <= ma->n1 * 2; ++k) + if (max1 < ma->z1[k]) max1 = ma->z1[k]; + for (k = 0, max2 = -1; k <= ma->M - ma->n1 * 2; ++k) + if (max2 < ma->z2[k]) max2 = ma->z2[k]; + rst->lrt = log(max1 * max2 / max0); + rst->lrt = rst->lrt < 0? 1 : kf_gammaq(.5, rst->lrt); + } else rst->lrt = -1.0; + rst->cmp[0] = rst->cmp[1] = rst->cmp[2] = rst->p_chi2 = -1.0; + if (do_contrast && rst->p_var > 0.5) // skip contrast2() if the locus is a strong non-variant + rst->p_chi2 = contrast2(ma, rst->cmp); + return 0; +} + +void bcf_p1_dump_afs(bcf_p1aux_t *ma) +{ + int k; + fprintf(stderr, "[afs]"); + for (k = 0; k <= ma->M; ++k) + fprintf(stderr, " %d:%.3lf", k, ma->afs[ma->M - k]); + fprintf(stderr, "\n"); + memset(ma->afs, 0, sizeof(double) * (ma->M + 1)); +} diff --git a/prob1.h b/prob1.h new file mode 100644 index 0000000..a3d4b0d --- /dev/null +++ b/prob1.h @@ -0,0 +1,93 @@ +/* prob1.h -- mathematical utility functions. + + Copyright (C) 2010, 2011 Broad Institute. + Copyright (C) 2012, 2013 Genome Research Ltd. + + Author: Heng Li + +Permission is hereby granted, free of charge, to any person obtaining a copy +of this software and associated documentation files (the "Software"), to deal +in the Software without restriction, including without limitation the rights +to use, copy, modify, merge, publish, distribute, sublicense, and/or sell +copies of the Software, and to permit persons to whom the Software is +furnished to do so, subject to the following conditions: + +The above copyright notice and this permission notice shall be included in +all copies or substantial portions of the Software. + +THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE +AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER +LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, +OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN +THE SOFTWARE. */ + +#ifndef BCF_PROB1_H +#define BCF_PROB1_H + +#include +#include "call.h" + +typedef struct { + int n; // Number of samples + int M; // Total number of chromosomes across all samples (n*2 if all samples are diploid) + int n1; + int is_indel; + uint8_t *ploidy; // haploid or diploid ONLY + double *q2p, *pdg; // q2p maps from phread scaled to real likelihood, pdg -> P(D|g) + double *phi; // Probability of seeing k reference alleles + double *phi_indel; + double *z, *zswap; // aux for afs + double *z1, *z2, *phi1, *phi2; // only calculated when n1 is set + double **hg; // hypergeometric distribution + double *lf; // log factorial + double t, t1, t2; + double *afs, *afs1; // afs: accumulative allele frequency spectrum (AFS); afs1: site posterior distribution + const int *PL; // point to PL + int PL_len; + int cons_llr; // pair and trio calling + int64_t cons_gt; +} bcf_p1aux_t; + +typedef struct { + int rank0, perm_rank; // NB: perm_rank is always set to -1 by bcf_p1_cal() + int ac; // ML alternative allele count + double f_exp, f_flat, p_ref_folded, p_ref, p_var_folded, p_var; + double cil, cih; + double cmp[3], p_chi2, lrt; // used by contrast2() +} bcf_p1rst_t; + +typedef struct { + double p[4]; + double edb, mqb, bqb; // end distance bias, mapQ bias, baseQ bias + int mq, depth, is_tested, d[4]; +} anno16_t; + +#define MC_PTYPE_FULL 1 +#define MC_PTYPE_COND2 2 +#define MC_PTYPE_FLAT 3 + +#ifdef __cplusplus +extern "C" { +#endif + + bcf_p1aux_t *bcf_p1_init(int n_smpl, uint8_t *ploidy); + void bcf_p1_init_prior(bcf_p1aux_t *ma, int type, double theta); + void bcf_p1_init_subprior(bcf_p1aux_t *ma, int type, double theta); + void bcf_p1_destroy(bcf_p1aux_t *ma); + void bcf_p1_set_ploidy(bcf1_t *b, bcf_p1aux_t *ma); + int bcf_p1_cal(call_t *call, bcf1_t *b, int do_contrast, bcf_p1aux_t *ma, bcf_p1rst_t *rst); + int bcf_p1_call_gt(const bcf_p1aux_t *ma, double f0, int k, int is_var); + void bcf_p1_dump_afs(bcf_p1aux_t *ma); + int bcf_p1_read_prior(bcf_p1aux_t *ma, const char *fn); + int bcf_p1_set_n1(bcf_p1aux_t *b, int n1); + void bcf_p1_set_folded(bcf_p1aux_t *p1a); // only effective when set_n1() is not called + + int bcf_em1(call_t *call, const bcf1_t *b, int n1, int flag, double x[10]); + +#ifdef __cplusplus +} +#endif + +#endif diff --git a/rbuf.h b/rbuf.h new file mode 100644 index 0000000..3d2805c --- /dev/null +++ b/rbuf.h @@ -0,0 +1,201 @@ +/* rbuf.h -- round buffers. + + Copyright (C) 2013-2014 Genome Research Ltd. + + Author: Petr Danecek + +Permission is hereby granted, free of charge, to any person obtaining a copy +of this software and associated documentation files (the "Software"), to deal +in the Software without restriction, including without limitation the rights +to use, copy, modify, merge, publish, distribute, sublicense, and/or sell +copies of the Software, and to permit persons to whom the Software is +furnished to do so, subject to the following conditions: + +The above copyright notice and this permission notice shall be included in +all copies or substantial portions of the Software. + +THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE +AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER +LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, +OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN +THE SOFTWARE. */ + +#ifndef __RBUF_H__ +#define __RBUF_H__ + +#include + +typedef struct +{ + int m,n,f; // m: allocated size, n: number of elements in the buffer, f: first element +} +rbuf_t; + +/** + * rbuf_init() - initialize round buffer + * @rbuf: the rbuf_t holder + * @size: the maximum number of elements + * + */ +static inline void rbuf_init(rbuf_t *rbuf, int size) +{ + rbuf->m = size; rbuf->n = rbuf->f = 0; +} +/** + * rbuf_kth() - get index of the k-th element of the round buffer + * @rbuf: the rbuf_t holder + * @k: 0-based index + */ +static inline int rbuf_kth(rbuf_t *rbuf, int k) +{ + if ( k >= rbuf->n || k<0 ) return -1; + int i = k + rbuf->f; + if ( i >= rbuf->m ) i -= rbuf->m; + return i; +} +/** + * rbuf_last() - get index of the last element of the round buffer + * @rbuf: the rbuf_t holder + * + */ +#define rbuf_last(rbuf) rbuf_kth(rbuf, (rbuf)->n - 1) + +/** + * rbuf_next() - get index of the next element in the round buffer + * @rbuf: the rbuf_t holder + * @i: pointer to the last rbuf index. Set to -1 before the first call. + * + * Sets i to the next position in the buffer. The return value indicates if + * the position points to a valid element (1) or if there are no more elements + * after *i (0). When the end is reached, *i is set to the first element in the + * buffer. + */ +static inline int rbuf_next(rbuf_t *rbuf, int *i) +{ + if ( !rbuf->n ) return 0; + if ( *i==-1 ) { *i = rbuf->f; return 1; } + int n = (rbuf->f <= *i) ? *i - rbuf->f + 1 : *i + rbuf->m - rbuf->f + 1; + if ( ++(*i) >= rbuf->m ) *i = 0; + if ( n < rbuf->n ) return 1; + *i = rbuf->f; + return 0; +} +/** + * rbuf_prev() - get index of the previous element in the round buffer + * @rbuf: the rbuf_t holder + * @i: pointer to the last rbuf index. Set to -1 before the first call. + * + * Sets i to the previous position in the buffer. The return value indicates if + * the position points to a valid element (1) or if there are no more elements + * before *i (0). + */ +static inline int rbuf_prev(rbuf_t *rbuf, int *i) +{ + if ( !rbuf->n || *i==rbuf->f ) return 0; + if ( *i==-1 ) + { + *i = rbuf_last(rbuf); + return 1; + } + if ( --(*i) < 0 ) *i = rbuf->m - 1; + return 1; +} +/** + * rbuf_prepend() - register new element at the start of the round buffer + * @rbuf: the rbuf_t holder + * + * Returns index of the newly inserted element. + */ +static inline int rbuf_prepend(rbuf_t *rbuf) +{ + if ( rbuf->n < rbuf->m ) rbuf->n++; + + rbuf->f = rbuf->f > 0 ? rbuf->f - 1 : rbuf->m - 1; + return rbuf->f; +} +/** + * rbuf_append() - register new element at the end of the round buffer + * @rbuf: the rbuf_t holder + * + * Returns index of the newly inserted element. + */ +static inline int rbuf_append(rbuf_t *rbuf) +{ + if ( rbuf->n < rbuf->m ) + { + rbuf->n++; + int i = rbuf->f + rbuf->n; + return i <= rbuf->m ? i - 1 : i - rbuf->m - 1; + } + + rbuf->f++; + if ( rbuf->f >= rbuf->m ) + { + rbuf->f = 0; + return rbuf->m - 1; + } + return rbuf->f - 1; +} +/** + * rbuf_shift() - removes first element from the buffer + * @rbuf: the rbuf_t holder + * + * Returns index of the removed element. + */ +static inline int rbuf_shift(rbuf_t *rbuf) +{ + if ( !rbuf->n ) return -1; + int ret = rbuf->f; + rbuf->f++; + if ( rbuf->f >= rbuf->m ) rbuf->f = 0; + rbuf->n--; + return ret; +} +/** + * rbuf_shift_n() - removes first n elements from the buffer + * @rbuf: the rbuf_t holder + * @n: number of elements to remove + */ +static inline void rbuf_shift_n(rbuf_t *rbuf, int n) +{ + if ( n >= rbuf->n ) + { + rbuf->n = rbuf->f = 0; + return; + } + rbuf->n -= n; + rbuf->f += n; + if ( rbuf->f >= rbuf->m ) rbuf->f -= rbuf->m; +} + +/** + * rbuf_expand0() - expand round buffer and set the newly allocated elements to 0 + * @rbuf: the rbuf holder + * @type_t: data type + * @n: requested number of elements + * @data: data array to be realloced + * + * Note: The new array is linearized and leaves the rbuf.f offset untouched, + * thus the size of the new buffer is determined by the current position. + */ +#define rbuf_expand0(rbuf,type_t,n,data) \ +{ \ + if ( n > (rbuf)->m ) \ + { \ + int m = n + (rbuf)->f; \ + m--, m|=m>>1, m|=m>>2, m|=m>>4, m|=m>>8, m|=m>>16, m++; /* kroundup32 */ \ + data = (type_t*) realloc(data, sizeof(type_t)*m); \ + type_t *ptr = data; \ + memset(ptr+(rbuf)->m,0,sizeof(type_t)*(m-(rbuf)->m)); \ + if ( (rbuf)->f ) \ + { \ + memcpy(ptr+(rbuf)->m,ptr,sizeof(type_t)*(rbuf)->f); \ + memset(ptr,0,sizeof(type_t)*(rbuf)->f); \ + } \ + (rbuf)->m = m; \ + } \ +} + +#endif diff --git a/regidx.c b/regidx.c new file mode 100644 index 0000000..84646a8 --- /dev/null +++ b/regidx.c @@ -0,0 +1,598 @@ +/* + Copyright (C) 2014-2016 Genome Research Ltd. + + Author: Petr Danecek + + Permission is hereby granted, free of charge, to any person obtaining a copy + of this software and associated documentation files (the "Software"), to deal + in the Software without restriction, including without limitation the rights + to use, copy, modify, merge, publish, distribute, sublicense, and/or sell + copies of the Software, and to permit persons to whom the Software is + furnished to do so, subject to the following conditions: + + The above copyright notice and this permission notice shall be included in + all copies or substantial portions of the Software. + + THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR + IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, + FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE + AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER + LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, + OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN + THE SOFTWARE. +*/ + +#include +#include +#include +#include +#include +#include "regidx.h" + +#define MAX_COOR_0 REGIDX_MAX // CSI and hts_itr_query limit, 0-based + +#define iBIN(x) ((x)>>13) + +typedef struct +{ + uint32_t beg, end; +} +reg_t; + +typedef struct +{ + uint32_t pos, ireg; // y-coordinate and a pointer to reglist.reg and reglist.dat +} +pos_t; + +typedef struct _reglist_t reglist_t; + +typedef struct +{ + uint32_t beg, end, ireg; // query coordinates and the active region + regidx_t *ridx; + reglist_t *list; + int active; +} +_itr_t; + +// List of regions for one chromosome. +struct _reglist_t +{ + uint32_t *idx, nidx; // index to list.reg+1 + uint32_t nreg, mreg; // n:used, m:allocated + reg_t *reg; // regions + void *dat; // payload data + char *seq; // sequence name + int unsorted; + +}; + +// Container of all sequences +struct _regidx_t +{ + int nseq, mseq; // n:used, m:alloced + reglist_t *seq; // regions for each sequence + void *seq2regs; // hash for fast lookup from chr name to regions + char **seq_names; + regidx_free_f free; // function to free any data allocated by regidx_parse_f + regidx_parse_f parse; // parse one input line + void *usr; // user data to pass to regidx_parse_f + int payload_size; + void *payload; // temporary payload data set by regidx_parse_f (sequence is not known beforehand) + kstring_t str; +}; + +int regidx_seq_nregs(regidx_t *idx, const char *seq) +{ + int iseq; + if ( khash_str2int_get(idx->seq2regs, seq, &iseq)!=0 ) return 0; // no such sequence + return idx->seq[iseq].nreg; +} + +int regidx_nregs(regidx_t *idx) +{ + int i, nreg = 0; + for (i=0; inseq; i++) nreg += idx->seq[i].nreg; + return nreg; +} + +char **regidx_seq_names(regidx_t *idx, int *n) +{ + *n = idx->nseq; + return idx->seq_names; +} + +int regidx_insert_list(regidx_t *idx, char *line, char delim) +{ + kstring_t tmp = {0,0,0}; + char *ss = line; + while ( *ss ) + { + char *se = ss; + while ( *se && *se!=delim ) se++; + tmp.l = 0; + kputsn(ss, se-ss, &tmp); + if ( regidx_insert(idx,tmp.s) < 0 ) + { + free(tmp.s); + return -1; + } + if ( !*se ) break; + ss = se+1; + } + free(tmp.s); + return 0; +} + +static inline int cmp_regs(reg_t *a, reg_t *b) +{ + if ( a->beg < b->beg ) return -1; + if ( a->beg > b->beg ) return 1; + if ( a->end < b->end ) return 1; // longer intervals come first + if ( a->end > b->end ) return -1; + return 0; +} +static int cmp_reg_ptrs(const void *a, const void *b) +{ + return cmp_regs((reg_t*)a,(reg_t*)b); +} +static int cmp_reg_ptrs2(const void *a, const void *b) +{ + return cmp_regs(*((reg_t**)a),*((reg_t**)b)); +} + +inline int regidx_push(regidx_t *idx, char *chr_beg, char *chr_end, uint32_t beg, uint32_t end, void *payload) +{ + if ( beg > MAX_COOR_0 ) beg = MAX_COOR_0; + if ( end > MAX_COOR_0 ) end = MAX_COOR_0; + + int rid; + idx->str.l = 0; + kputsn(chr_beg, chr_end-chr_beg+1, &idx->str); + if ( khash_str2int_get(idx->seq2regs, idx->str.s, &rid)!=0 ) + { + // new chromosome + idx->nseq++; + int m_prev = idx->mseq; + hts_expand0(reglist_t,idx->nseq,idx->mseq,idx->seq); + hts_expand0(char*,idx->nseq,m_prev,idx->seq_names); + idx->seq_names[idx->nseq-1] = strdup(idx->str.s); + rid = khash_str2int_inc(idx->seq2regs, idx->seq_names[idx->nseq-1]); + } + + reglist_t *list = &idx->seq[rid]; + list->seq = idx->seq_names[rid]; + list->nreg++; + int mreg = list->mreg; + hts_expand(reg_t,list->nreg,list->mreg,list->reg); + list->reg[list->nreg-1].beg = beg; + list->reg[list->nreg-1].end = end; + if ( idx->payload_size ) + { + if ( mreg != list->mreg ) list->dat = realloc(list->dat,idx->payload_size*list->mreg); + memcpy((char *)list->dat + idx->payload_size*(list->nreg-1), payload, idx->payload_size); + } + if ( !list->unsorted && list->nreg>1 && cmp_regs(&list->reg[list->nreg-2],&list->reg[list->nreg-1])>0 ) list->unsorted = 1; + return 0; +} + +int regidx_insert(regidx_t *idx, char *line) +{ + if ( !line ) return 0; + char *chr_from, *chr_to; + uint32_t beg,end; + int ret = idx->parse(line,&chr_from,&chr_to,&beg,&end,idx->payload,idx->usr); + if ( ret==-2 ) return -1; // error + if ( ret==-1 ) return 0; // skip the line + regidx_push(idx, chr_from,chr_to,beg,end,idx->payload); + return 0; +} + +regidx_t *regidx_init(const char *fname, regidx_parse_f parser, regidx_free_f free_f, size_t payload_size, void *usr_dat) +{ + if ( !parser ) + { + if ( !fname ) parser = regidx_parse_tab; + else + { + int len = strlen(fname); + if ( len>=7 && !strcasecmp(".bed.gz",fname+len-7) ) + parser = regidx_parse_bed; + else if ( len>=8 && !strcasecmp(".bed.bgz",fname+len-8) ) + parser = regidx_parse_bed; + else if ( len>=4 && !strcasecmp(".bed",fname+len-4) ) + parser = regidx_parse_bed; + else + parser = regidx_parse_tab; + } + } + + regidx_t *idx = (regidx_t*) calloc(1,sizeof(regidx_t)); + idx->free = free_f; + idx->parse = parser; + idx->usr = usr_dat; + idx->seq2regs = khash_str2int_init(); + idx->payload_size = payload_size; + if ( payload_size ) idx->payload = malloc(payload_size); + + if ( !fname ) return idx; + + kstring_t str = {0,0,0}; + + htsFile *fp = hts_open(fname,"r"); + if ( !fp ) goto error; + + while ( hts_getline(fp, KS_SEP_LINE, &str) > 0 ) + { + if ( regidx_insert(idx, str.s) ) goto error; + } + + free(str.s); + hts_close(fp); + return idx; + +error: + free(str.s); + if ( fp ) hts_close(fp); + regidx_destroy(idx); + return NULL; +} + +void regidx_destroy(regidx_t *idx) +{ + int i, j; + for (i=0; inseq; i++) + { + reglist_t *list = &idx->seq[i]; + if ( idx->free ) + { + for (j=0; jnreg; j++) + idx->free((char *)list->dat + idx->payload_size*j); + } + free(list->dat); + free(list->reg); + free(list->idx); + } + free(idx->seq_names); + free(idx->seq); + free(idx->str.s); + free(idx->payload); + khash_str2int_destroy_free(idx->seq2regs); + free(idx); +} + +int _reglist_build_index(regidx_t *regidx, reglist_t *list) +{ + int i; + if ( list->unsorted ) + { + if ( !regidx->payload_size ) + qsort(list->reg,list->nreg,sizeof(reg_t),cmp_reg_ptrs); + else + { + reg_t **ptr = (reg_t**) malloc(sizeof(reg_t*)*list->nreg); + for (i=0; inreg; i++) ptr[i] = list->reg + i; + qsort(ptr,list->nreg,sizeof(*ptr),cmp_reg_ptrs2); + + void *tmp_dat = malloc(regidx->payload_size*list->nreg); + for (i=0; inreg; i++) + { + size_t iori = ptr[i] - list->reg; + memcpy((char *)tmp_dat+i*regidx->payload_size, + (char *)list->dat+iori*regidx->payload_size, + regidx->payload_size); + } + free(list->dat); + list->dat = tmp_dat; + + reg_t *tmp_reg = (reg_t*) malloc(sizeof(reg_t)*list->nreg); + for (i=0; inreg; i++) + { + size_t iori = ptr[i] - list->reg; + tmp_reg[i] = list->reg[iori]; + } + free(ptr); + free(list->reg); + list->reg = tmp_reg; + list->mreg = list->nreg; + } + list->unsorted = 0; + } + + list->nidx = 0; + int j,k, midx = 0; + for (j=0; jnreg; j++) + { + int ibeg = iBIN(list->reg[j].beg); + int iend = iBIN(list->reg[j].end); + if ( midx <= iend ) + { + int old_midx = midx; + midx = iend + 1; + kroundup32(midx); + list->idx = (uint32_t*) realloc(list->idx, midx*sizeof(uint32_t)); + memset(list->idx+old_midx, 0, sizeof(uint32_t)*(midx-old_midx)); + } + if ( ibeg==iend ) + { + if ( !list->idx[ibeg] ) list->idx[ibeg] = j + 1; + } + else + { + for (k=ibeg; k<=iend; k++) + if ( !list->idx[k] ) list->idx[k] = j + 1; + } + if ( list->nidx < iend+1 ) list->nidx = iend+1; + } + + return 0; +} + +int regidx_overlap(regidx_t *regidx, const char *chr, uint32_t beg, uint32_t end, regitr_t *regitr) +{ + if ( regitr ) regitr->seq = NULL; + + int iseq, ireg; + if ( khash_str2int_get(regidx->seq2regs, chr, &iseq)!=0 ) return 0; // no such sequence + + reglist_t *list = ®idx->seq[iseq]; + if ( !list->nreg ) return 0; + + if ( list->nreg==1 ) + { + if ( beg > list->reg[0].end ) return 0; + if ( end < list->reg[0].beg ) return 0; + ireg = 0; + } + else + { + if ( !list->idx ) + _reglist_build_index(regidx,list); + + int ibeg = iBIN(beg); + if ( ibeg >= list->nidx ) return 0; // beg is too big + + // find a matching region + uint32_t i = list->idx[ibeg]; + if ( !i ) + { + int iend = iBIN(end); + if ( iend > list->nidx ) iend = list->nidx; + for (i=ibeg; iidx[i] ) break; + if ( i==iend ) return 0; + i = list->idx[i]; + } + + for (ireg=i-1; iregnreg; ireg++) + { + if ( list->reg[ireg].beg > end ) return 0; // no match, past the query region + if ( list->reg[ireg].end >= beg && list->reg[ireg].beg <= end ) break; // found + } + + if ( ireg >= list->nreg ) return 0; // no match + } + + if ( !regitr ) return 1; // match, but no more info to save + + // may need to iterate over the matching regions later + _itr_t *itr = (_itr_t*)regitr->itr; + itr->ridx = regidx; + itr->list = list; + itr->beg = beg; + itr->end = end; + itr->ireg = ireg; + itr->active = 0; + + regitr->seq = list->seq; + regitr->beg = list->reg[ireg].beg; + regitr->end = list->reg[ireg].end; + if ( regidx->payload_size ) + regitr->payload = (char *)list->dat + regidx->payload_size*ireg; + + return 1; +} + +int regidx_parse_bed(const char *line, char **chr_beg, char **chr_end, uint32_t *beg, uint32_t *end, void *payload, void *usr) +{ + char *ss = (char*) line; + while ( *ss && isspace(*ss) ) ss++; + if ( !*ss ) return -1; // skip blank lines + if ( *ss=='#' ) return -1; // skip comments + + char *se = ss; + while ( *se && !isspace(*se) ) se++; + + *chr_beg = ss; + *chr_end = se-1; + + if ( !*se ) + { + // just the chromosome name + *beg = 0; + *end = MAX_COOR_0; + return 0; + } + + ss = se+1; + *beg = strtod(ss, &se); + if ( ss==se ) { fprintf(stderr,"Could not parse bed line: %s\n", line); return -2; } + + ss = se+1; + *end = strtod(ss, &se) - 1; + if ( ss==se ) { fprintf(stderr,"Could not parse bed line: %s\n", line); return -2; } + + return 0; +} + +int regidx_parse_tab(const char *line, char **chr_beg, char **chr_end, uint32_t *beg, uint32_t *end, void *payload, void *usr) +{ + char *ss = (char*) line; + while ( *ss && isspace(*ss) ) ss++; + if ( !*ss ) return -1; // skip blank lines + if ( *ss=='#' ) return -1; // skip comments + + char *se = ss; + while ( *se && !isspace(*se) ) se++; + + *chr_beg = ss; + *chr_end = se-1; + + if ( !*se ) + { + // just the chromosome name + *beg = 0; + *end = MAX_COOR_0; + return 0; + } + + ss = se+1; + *beg = strtod(ss, &se); + if ( ss==se ) { fprintf(stderr,"Could not parse tab line: %s\n", line); return -2; } + if ( *beg==0 ) { fprintf(stderr,"Could not parse tab line, expected 1-based coordinate: %s\n", line); return -2; } + (*beg)--; + + if ( !se[0] || !se[1] ) + *end = *beg; + else + { + ss = se+1; + *end = strtod(ss, &se); + if ( ss==se ) *end = *beg; + else if ( *end==0 ) { fprintf(stderr,"Could not parse tab line, expected 1-based coordinate: %s\n", line); return -2; } + else (*end)--; + } + return 0; +} + +int regidx_parse_reg(const char *line, char **chr_beg, char **chr_end, uint32_t *beg, uint32_t *end, void *payload, void *usr) +{ + char *ss = (char*) line; + while ( *ss && isspace(*ss) ) ss++; + if ( !*ss ) return -1; // skip blank lines + if ( *ss=='#' ) return -1; // skip comments + + char *se = ss; + while ( *se && *se!=':' ) se++; + + *chr_beg = ss; + *chr_end = se-1; + + if ( !*se ) + { + *beg = 0; + *end = MAX_COOR_0; + return 0; + } + + ss = se+1; + *beg = strtod(ss, &se); + if ( ss==se ) { fprintf(stderr,"Could not parse reg line: %s\n", line); return -2; } + if ( *beg==0 ) { fprintf(stderr,"Could not parse reg line, expected 1-based coordinate: %s\n", line); return -2; } + (*beg)--; + + if ( !se[0] || !se[1] ) + *end = se[0]=='-' ? MAX_COOR_0 : *beg; + else + { + ss = se+1; + *end = strtod(ss, &se); + if ( ss==se ) *end = *beg; + else if ( *end==0 ) { fprintf(stderr,"Could not parse reg line, expected 1-based coordinate: %s\n", line); return -2; } + else (*end)--; + } + return 0; +} + +regitr_t *regitr_init(regidx_t *regidx) +{ + regitr_t *regitr = (regitr_t*) calloc(1,sizeof(regitr_t)); + regitr->itr = (_itr_t*) calloc(1,sizeof(_itr_t)); + _itr_t *itr = (_itr_t*) regitr->itr; + itr->ridx = regidx; + itr->list = NULL; + return regitr; +} + +void regitr_reset(regidx_t *regidx, regitr_t *regitr) +{ + _itr_t *itr = (_itr_t*) regitr->itr; + memset(itr,0,sizeof(_itr_t)); + itr->ridx = regidx; +} + +void regitr_destroy(regitr_t *regitr) +{ + free(regitr->itr); + free(regitr); +} + +int regitr_overlap(regitr_t *regitr) +{ + if ( !regitr->seq ) return 0; + + _itr_t *itr = (_itr_t*) regitr->itr; + if ( !itr->active ) + { + // is this the first call after regidx_overlap? + itr->active = 1; + itr->ireg++; + return 1; + } + + reglist_t *list = itr->list; + + int i; + for (i=itr->ireg; inreg; i++) + { + if ( list->reg[i].beg > itr->end ) return 0; // no match, past the query region + if ( list->reg[i].end >= itr->beg && list->reg[i].beg <= itr->end ) break; // found + } + + if ( i >= list->nreg ) return 0; // no match + + itr->ireg = i + 1; + regitr->seq = list->seq; + regitr->beg = list->reg[i].beg; + regitr->end = list->reg[i].end; + if ( itr->ridx->payload_size ) + regitr->payload = (char *)list->dat + itr->ridx->payload_size*i; + + return 1; +} + +int regitr_loop(regitr_t *regitr) +{ + _itr_t *itr = (_itr_t*) regitr->itr; + regidx_t *regidx = itr->ridx; + + if ( !itr->list ) // first time here + { + itr->list = regidx->seq; + itr->ireg = 0; + } + + size_t iseq = itr->list - regidx->seq; + if ( iseq >= regidx->nseq ) return 0; + + if ( itr->ireg >= itr->list->nreg ) + { + iseq++; + if ( iseq >= regidx->nseq ) return 0; // no more sequences, done + itr->ireg = 0; + itr->list = ®idx->seq[iseq]; + } + + regitr->seq = itr->list->seq; + regitr->beg = itr->list->reg[itr->ireg].beg; + regitr->end = itr->list->reg[itr->ireg].end; + if ( regidx->payload_size ) + regitr->payload = (char *)itr->list->dat + regidx->payload_size*itr->ireg; + itr->ireg++; + + return 1; +} + + + diff --git a/regidx.h b/regidx.h new file mode 100644 index 0000000..8e25fe1 --- /dev/null +++ b/regidx.h @@ -0,0 +1,191 @@ +/* + Copyright (C) 2014-2016 Genome Research Ltd. + + Author: Petr Danecek + + Permission is hereby granted, free of charge, to any person obtaining a copy + of this software and associated documentation files (the "Software"), to deal + in the Software without restriction, including without limitation the rights + to use, copy, modify, merge, publish, distribute, sublicense, and/or sell + copies of the Software, and to permit persons to whom the Software is + furnished to do so, subject to the following conditions: + + The above copyright notice and this permission notice shall be included in + all copies or substantial portions of the Software. + + THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR + IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, + FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE + AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER + LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, + OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN + THE SOFTWARE. +*/ + +/* + Region indexing with an optional payload. + + Example of usage: + + // Init the parser and print regions. In this example the payload is a + // pointer to a string. For the description of parse_custom and + // free_custom functions, see regidx_parse_f and regidx_free_f below, + // and for working example see test/test-regidx.c. + regidx_t *idx = regidx_init(in_fname,parse_custom,free_custom,sizeof(char*),NULL); + + // Query overlap with chr:from-to + regitr_t *itr = regitr_init(idx); + if ( regidx_overlap(idx, chr,from,to, itr) ) printf("There is an overlap!\n"); + + while ( regitr_overlap(itr) ) + { + printf("[%d,%d] overlaps with [%d,%d], payload=%s\n", from,to, + itr->beg, itr->end, regitr_payload(itr,char*)); + } + + regidx_destroy(idx); + regitr_destroy(itr); + + + Another example, loop over all regions: + + regidx_t *idx = regidx_init(in_fname,NULL,NULL,0,NULL); + regitr_t *itr = regitr_init(idx); + + while ( regitr_loop(itr) ) + printf("chr=%s beg=%d end=%d\n", itr->seq, itr->beg, itr->end); + + regidx_destroy(idx); + regitr_destroy(itr); +*/ + +#ifndef __REGIDX_H__ +#define __REGIDX_H__ + +#include +#include + +#ifdef __cplusplus +extern "C" { +#endif + +#define REGIDX_MAX 2147483646 // maximum regidx coordinate (0-based) + +typedef struct _regidx_t regidx_t; +typedef struct +{ + uint32_t beg,end; + void *payload; + char *seq; + void *itr; +} +regitr_t; + +#define regitr_payload(itr,type_t) (*((type_t*)(itr)->payload)) + +/* + * regidx_parse_f - Function to parse one input line, such as regidx_parse_bed + * or regidx_parse_tab below. The function is expected to set `chr_from` and + * `chr_to` to point to first and last character of chromosome name and set + * coordinates `beg` and `end` (0-based, inclusive). If regidx_init() was + * called with non-zero payload_size, the `payload` points to a memory + * location of the payload_size and `usr` is the data passed to regidx_init(). + * Any memory allocated by the function will be freed by regidx_free_f called + * by regidx_destroy(). + * + * Return value: 0 on success, -1 to skip a record, -2 on fatal error. + */ +typedef int (*regidx_parse_f)(const char *line, char **chr_beg, char **chr_end, uint32_t *beg, uint32_t *end, void *payload, void *usr); +typedef void (*regidx_free_f)(void *payload); + +/* + * A note about the parsers: + * - leading spaces are ignored + * - lines starting with "#" are ignored + */ +int regidx_parse_bed(const char*,char**,char**,uint32_t*,uint32_t*,void*,void*); // CHROM or whitespace-sepatated CHROM,FROM,TO (0-based,right-open) +int regidx_parse_tab(const char*,char**,char**,uint32_t*,uint32_t*,void*,void*); // CHROM or whitespace-separated CHROM,POS (1-based, inclusive) +int regidx_parse_reg(const char*,char**,char**,uint32_t*,uint32_t*,void*,void*); // CHROM, CHROM:POS, CHROM:FROM-TO, CHROM:FROM- (1-based, inclusive) + +/* + * regidx_init() - creates new index + * @param fname: input file name or NULL if regions will be added one-by-one via regidx_insert() + * @param parsef: regidx_parse_bed, regidx_parse_tab or see description of regidx_parse_f. If NULL, + * the format will be autodected, currently either regidx_parse_tab (the default) or + * regidx_parse_bed (file must be named 'bed' or 'bed.gz') will be used. Note that + * the exact autodetection algorithm will change. + * @param freef: NULL or see description of regidx_parse_f + * @param payload_size: 0 with regidx_parse_bed, regidx_parse_tab or see regidx_parse_f + * @param usr: optional user data passed to regidx_parse_f + * + * Returns index on success or NULL on error. + */ +regidx_t *regidx_init(const char *fname, regidx_parse_f parsef, regidx_free_f freef, size_t payload_size, void *usr); + +/* + * regidx_destroy() - free memory allocated by regidx_init + */ +void regidx_destroy(regidx_t *idx); + +/* + * regidx_overlap() - check overlap of the location chr:from-to with regions + * @param beg,end: 0-based start, end coordinate (inclusive) + * @param itr: pointer to iterator, can be NULL if regidx_loop not needed + * + * Returns 0 if there is no overlap or 1 if overlap is found. The overlapping + * regions can be iterated as shown in the example above. + */ +int regidx_overlap(regidx_t *idx, const char *chr, uint32_t beg, uint32_t end, regitr_t *itr); + +/* + * regidx_insert() - add a new region. + * regidx_insert_list() - add new regions from a list + * regidx_push() - low level insertion of a new region + * + * Returns 0 on success or -1 on error. + */ +int regidx_insert(regidx_t *idx, char *line); +int regidx_insert_list(regidx_t *idx, char *line, char delim); +int regidx_push(regidx_t *idx, char *chr_beg, char *chr_end, uint32_t beg, uint32_t end, void *payload); + +/* + * regidx_seq_names() - return list of all sequence names + */ +char **regidx_seq_names(regidx_t *idx, int *n); + +/* + * regidx_seq_nregs() - number of regions + * regidx_nregs() - total number of regions + */ +int regidx_seq_nregs(regidx_t *idx, const char *seq); +int regidx_nregs(regidx_t *idx); + +/* + * regitr_init() - initialize an iterator. The idx parameter is required only + * with regitr_loop. If only regitr_overlap is called, NULL + * can be given. + * + * regitr_reset() - initialize an iterator for a repeated regitr_loop cycle. + * Not required with regitr_overlap. + */ +regitr_t *regitr_init(regidx_t *idx); +void regitr_destroy(regitr_t *itr); +void regitr_reset(regidx_t *idx, regitr_t *itr); + +/* + * regitr_overlap() - next overlapping region + * Returns 0 when done or 1 when itr is set to next region + */ +int regitr_overlap(regitr_t *itr); + +/* + * regitr_loop() - loop over all regions + * Returns 0 when done or 1 when itr is set to next region + */ +int regitr_loop(regitr_t *itr); + +#ifdef __cplusplus +} +#endif + +#endif diff --git a/reheader.c b/reheader.c new file mode 100644 index 0000000..429bf7e --- /dev/null +++ b/reheader.c @@ -0,0 +1,521 @@ +/* reheader.c -- reheader subcommand. + + Copyright (C) 2014,2016 Genome Research Ltd. + + Author: Petr Danecek + +Permission is hereby granted, free of charge, to any person obtaining a copy +of this software and associated documentation files (the "Software"), to deal +in the Software without restriction, including without limitation the rights +to use, copy, modify, merge, publish, distribute, sublicense, and/or sell +copies of the Software, and to permit persons to whom the Software is +furnished to do so, subject to the following conditions: + +The above copyright notice and this permission notice shall be included in +all copies or substantial portions of the Software. + +THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE +AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER +LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, +OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN +THE SOFTWARE. */ + +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include // for hts_get_bgzfp() +#include +#include "bcftools.h" +#include "khash_str2str.h" + +typedef struct _args_t +{ + char **argv, *fname, *samples_fname, *header_fname, *output_fname; + htsFile *fp; + htsFormat type; + int argc; +} +args_t; + +static void read_header_file(char *fname, kstring_t *hdr) +{ + kstring_t tmp = {0,0,0}; + hdr->l = 0; + + htsFile *fp = hts_open(fname, "r"); + if ( !fp ) error("Could not read: %s\n", fname); + while ( hts_getline(fp, KS_SEP_LINE, &tmp) > 0 ) + { + kputsn(tmp.s,tmp.l,hdr); + kputc('\n',hdr); + } + if ( hts_close(fp) ) error("Close failed: %s\n", fname); + free(tmp.s); + + while ( hdr->l>0 && isspace(hdr->s[hdr->l-1]) ) hdr->l--; // remove trailing newlines + kputc('\n',hdr); +} + +static int set_sample_pairs(char **samples, int nsamples, kstring_t *hdr, int idx) +{ + int i, j, n; + kstring_t key = {0,0,0}; + kstring_t val = {0,0,0}; + + // Are these samples "old-name new-name" pairs? + void *hash = khash_str2str_init(); + for (i=0; il>0 && isspace(hdr->s[hdr->l-1]) ) hdr->l--; // remove trailing newlines + hdr->s[hdr->l] = 0; + + kstring_t tmp = {0,0,0}; + i = j = n = 0; + while ( hdr->s[idx+i] && hdr->s[idx+i]) + { + if ( hdr->s[idx+i]=='\t' ) + { + hdr->s[idx+i] = 0; + + if ( ++n>9 ) + { + char *ori = khash_str2str_get(hash,hdr->s+idx+j); + kputs(ori ? ori : hdr->s+idx+j, &tmp); + } + else + kputs(hdr->s+idx+j, &tmp); + + kputc('\t',&tmp); + + j = ++i; + continue; + } + i++; + } + char *ori = khash_str2str_get(hash,hdr->s+idx+j); + kputs(ori ? ori : hdr->s+idx+j, &tmp); + + khash_str2str_destroy_free_all(hash); + + hdr->l = idx; + kputs(tmp.s, hdr); + kputc('\n', hdr); + free(tmp.s); + + return 1; +} + +static void set_samples(char **samples, int nsamples, kstring_t *hdr) +{ + // Find the beginning of the #CHROM line + int i = hdr->l - 2, ncols = 0; + while ( i>=0 && hdr->s[i]!='\n' ) + { + if ( hdr->s[i]=='\t' ) ncols++; + i--; + } + if ( i<0 || strncmp(hdr->s+i+1,"#CHROM\tPOS\tID\tREF\tALT\tQUAL\tFILTER\tINFO\tFORMAT",45) ) error("Could not parse the header: %s\n", hdr->s); + + // Are the samples "old-sample new-sample" pairs? + if ( set_sample_pairs(samples,nsamples,hdr, i+1) ) return; + + // Replace all samples + if ( ncols!=nsamples+8 ) + fprintf(stderr, "Warning: different number of samples: %d vs %d\n", nsamples,ncols-8); + + ncols = 0; + while ( ncols!=9 ) + { + i++; + if ( hdr->s[i]=='\t' ) ncols++; + } + hdr->l = i; + + for (i=0; ifp); + if ( !fp || bgzf_read_block(fp) != 0 || !fp->block_length ) + error("Failed to read %s: %s\n", args->fname, strerror(errno)); + + kstring_t hdr = {0,0,0}; + char *buffer = (char*) fp->uncompressed_block; + + // Read the header and find the position of the data block + if ( buffer[0]!='#' ) error("Could not parse the header, expected '#', found '%c'\n", buffer[0]); + + int skip_until = 1; // end of the header in the current uncompressed block + while (1) + { + if ( buffer[skip_until]=='\n' ) + { + skip_until++; + if ( skip_until>=fp->block_length ) + { + kputsn(buffer,skip_until,&hdr); + if ( bgzf_read_block(fp) != 0 ) error("Error reading %s\n", args->fname); + if ( !fp->block_length ) break; + skip_until = 0; + } + // The header has finished + if ( buffer[skip_until]!='#' ) + { + kputsn(buffer,skip_until,&hdr); + break; + } + } + skip_until++; + if ( skip_until>=fp->block_length ) + { + kputsn(buffer,fp->block_length,&hdr); + if ( bgzf_read_block(fp) != 0 ) error("Error reading %s\n", args->fname); + if ( !fp->block_length ) break; + skip_until = 0; + } + } + + int nsamples = 0; + char **samples = NULL; + if ( args->samples_fname ) + samples = hts_readlines(args->samples_fname, &nsamples); + if ( args->header_fname ) + { + free(hdr.s); hdr.s = NULL; hdr.l = hdr.m = 0; + read_header_file(args->header_fname, &hdr); + } + if ( samples ) + { + set_samples(samples, nsamples, &hdr); + int i; + for (i=0; ioutput_fname ? args->output_fname : "-","w");; + if ( bgzf_write(bgzf_out, hdr.s, hdr.l) < 0 ) error("Can't write BGZF header (code %d)\n", bgzf_out->errcode); + free(hdr.s); + + // Output all remainig data read with the header block + if ( fp->block_length - skip_until > 0 ) + { + if ( bgzf_write(bgzf_out, buffer+skip_until, fp->block_length-skip_until)<0 ) error("Error: %d\n",fp->errcode); + } + if ( bgzf_flush(bgzf_out)<0 ) error("Error: %d\n",bgzf_out->errcode); + + // Stream the rest of the file without as it is, without decompressing + ssize_t nread; + const size_t page_size = 32768; + char *buf = (char*) malloc(page_size); + while (1) + { + nread = bgzf_raw_read(fp, buf, page_size); + if ( nread<=0 ) break; + + int count = bgzf_raw_write(bgzf_out, buf, nread); + if (count != nread) error("Write failed, wrote %d instead of %d bytes.\n", count,(int)nread); + } + if (bgzf_close(bgzf_out) < 0) error("Error closing %s: %d\n",args->output_fname ? args->output_fname : "-",bgzf_out->errcode); + if (hts_close(args->fp)) error("Error closing %s: %d\n",args->fname,fp->errcode); + free(buf); +} +static void reheader_vcf(args_t *args) +{ + kstring_t hdr = {0,0,0}; + htsFile *fp = args->fp; + while ( hts_getline(fp, KS_SEP_LINE, &fp->line) >=0 ) + { + kputc('\n',&fp->line); // hts_getline eats the newline character + if ( fp->line.s[0]!='#' ) break; + kputsn(fp->line.s,fp->line.l,&hdr); + } + + int nsamples = 0; + char **samples = NULL; + if ( args->samples_fname ) + samples = hts_readlines(args->samples_fname, &nsamples); + if ( args->header_fname ) + { + free(hdr.s); hdr.s = NULL; hdr.l = hdr.m = 0; + read_header_file(args->header_fname, &hdr); + } + if ( samples ) + { + set_samples(samples, nsamples, &hdr); + int i; + for (i=0; ioutput_fname ? open(args->output_fname, O_WRONLY|O_CREAT|O_TRUNC, 0666) : STDOUT_FILENO; + if ( out==-1 ) error("%s: %s\n", args->output_fname,strerror(errno)); + if ( write(out, hdr.s, hdr.l)!=hdr.l ) error("Failed to write %d bytes\n", hdr.l); + free(hdr.s); + if ( fp->line.l ) + { + if ( write(out, fp->line.s, fp->line.l)!=fp->line.l ) error("Failed to write %d bytes\n", fp->line.l); + } + while ( hts_getline(fp, KS_SEP_LINE, &fp->line) >=0 ) // uncompressed file implies small size, we don't worry about speed + { + kputc('\n',&fp->line); + if ( write(out, fp->line.s, fp->line.l)!=fp->line.l ) error("Failed to write %d bytes\n", fp->line.l); + } + hts_close(fp); + close(out); +} + +static bcf_hdr_t *strip_header(bcf_hdr_t *src, bcf_hdr_t *dst) +{ + bcf_hrec_t *src_hrec, *dst_hrec, *tmp; + bcf_hdr_t *out = bcf_hdr_init("r"); + int i; + for (i=0; inhrec; i++) + { + // first insert lines which do not code BCF ids, their order does not matter + dst_hrec = dst->hrec[i]; + if ( dst_hrec->type==BCF_HL_FLT || dst_hrec->type==BCF_HL_INFO || dst_hrec->type==BCF_HL_FMT || dst_hrec->type== BCF_HL_CTG ) continue; + bcf_hdr_add_hrec(out, bcf_hrec_dup(dst_hrec)); + } + for (i=0; inhrec; i++) + { + // now transfer header lines which define BCF ids + src_hrec = src->hrec[i]; + + if ( src_hrec->type==BCF_HL_FLT || src_hrec->type==BCF_HL_INFO || src_hrec->type==BCF_HL_FMT || src_hrec->type== BCF_HL_CTG ) + { + int j = bcf_hrec_find_key(src_hrec, "ID"); + dst_hrec = bcf_hdr_get_hrec(dst, src_hrec->type, "ID", src_hrec->vals[j], NULL); + if ( !dst_hrec ) continue; + + tmp = bcf_hrec_dup(dst_hrec); + + j = bcf_hrec_find_key(src_hrec, "IDX"); + if ( j>=0 ) + { + j = atoi(src_hrec->vals[j]); + hrec_add_idx(tmp, j); + } + bcf_hdr_add_hrec(out, tmp); + } + } + bcf_hdr_sync(out); + for (i=0; inhrec; i++) + { + // finally add new structured fields + dst_hrec = dst->hrec[i]; + if ( dst_hrec->type==BCF_HL_FLT || dst_hrec->type==BCF_HL_INFO || dst_hrec->type==BCF_HL_FMT || dst_hrec->type== BCF_HL_CTG ) + { + int j = bcf_hrec_find_key(dst_hrec, "ID"); + tmp = bcf_hdr_get_hrec(out, dst_hrec->type, "ID", dst_hrec->vals[j], NULL); + if ( !tmp ) + bcf_hdr_add_hrec(out, bcf_hrec_dup(dst_hrec)); + } + } + for (i=0; in[BCF_DT_SAMPLE]; i++) bcf_hdr_add_sample(out, dst->samples[i]); + bcf_hdr_destroy(dst); + return out; +} + +static void reheader_bcf(args_t *args, int is_compressed) +{ + htsFile *fp = args->fp; + bcf_hdr_t *hdr = bcf_hdr_read(fp); if ( !hdr ) error("Failed to read the header: %s\n", args->fname); + kstring_t htxt = {0,0,0}; + bcf_hdr_format(hdr, 1, &htxt); + + int i, nsamples = 0; + char **samples = NULL; + if ( args->samples_fname ) + samples = hts_readlines(args->samples_fname, &nsamples); + if ( args->header_fname ) + { + free(htxt.s); htxt.s = NULL; htxt.l = htxt.m = 0; + read_header_file(args->header_fname, &htxt); + } + if ( samples ) + { + set_samples(samples, nsamples, &htxt); + for (i=0; iheader_fname ) hdr_out = strip_header(hdr, hdr_out); + + // write the header and the body + htsFile *fp_out = hts_open(args->output_fname ? args->output_fname : "-",is_compressed ? "wb" : "wbu"); + if ( !fp_out ) error("%s: %s\n", args->output_fname ? args->output_fname : "-", strerror(errno)); + bcf_hdr_write(fp_out, hdr_out); + + bcf1_t *rec = bcf_init(); + while ( bcf_read(fp, hdr, rec)==0 ) + { + // sanity checking, this slows things down. Make it optional? + bcf_unpack(rec, BCF_UN_ALL); + if ( rec->rid >= hdr_out->n[BCF_DT_CTG] || strcmp(bcf_hdr_int2id(hdr,BCF_DT_CTG,rec->rid),bcf_hdr_int2id(hdr_out,BCF_DT_CTG,rec->rid)) ) + error("The CHROM is not defined: \"%s\"\n", bcf_hdr_int2id(hdr,BCF_DT_CTG,rec->rid)); + + for (i=0; id.n_flt; i++) + { + int id = rec->d.flt[i]; + if ( id >= hdr_out->n[BCF_DT_ID] ) break; + if ( !bcf_hdr_idinfo_exists(hdr_out,BCF_HL_FLT,id) ) break; + if ( strcmp(hdr->id[BCF_DT_ID][id].key,hdr_out->id[BCF_DT_ID][id].key) ) + error("FIXME: Broken FILTER ids: %s vs %s\n", hdr->id[BCF_DT_ID][id].key,hdr_out->id[BCF_DT_ID][id].key); + } + if ( i!=rec->d.n_flt ) + error("The FILTER is not defined: \"%s\"\n", bcf_hdr_int2id(hdr,BCF_DT_ID,rec->d.flt[i])); + + for (i=0; in_info; i++) + { + int id = rec->d.info[i].key; + if ( id >= hdr_out->n[BCF_DT_ID] ) break; + if ( !hdr_out->id[BCF_DT_ID][id].key ) break; + if ( !bcf_hdr_idinfo_exists(hdr_out,BCF_HL_INFO,id) ) break; + if ( strcmp(hdr->id[BCF_DT_ID][id].key,hdr_out->id[BCF_DT_ID][id].key) ) + error("FIXME: Broken INFO ids: %s vs %s\n", hdr->id[BCF_DT_ID][id].key,hdr_out->id[BCF_DT_ID][id].key); + } + if ( i!=rec->n_info ) + error("The INFO tag is not defined: \"%s\"\n", bcf_hdr_int2id(hdr,BCF_DT_ID,rec->d.info[i].key)); + + for (i=0; in_fmt; i++) + { + int id = rec->d.fmt[i].id; + if ( id >= hdr_out->n[BCF_DT_ID] ) break; + if ( !hdr_out->id[BCF_DT_ID][id].key ) break; + if ( !bcf_hdr_idinfo_exists(hdr_out,BCF_HL_FMT,id) ) break; + if ( strcmp(hdr->id[BCF_DT_ID][id].key,hdr_out->id[BCF_DT_ID][id].key) ) + error("FIXME: Broken FORMAT ids: %s vs %s\n", hdr->id[BCF_DT_ID][id].key,hdr_out->id[BCF_DT_ID][id].key); + } + if ( i!=rec->n_fmt ) + error("The FORMAT tag is not defined: \"%s\"\n", bcf_hdr_int2id(hdr,BCF_DT_ID,rec->d.fmt[i].id)); + + bcf_write(fp_out,hdr_out,rec); + } + bcf_destroy(rec); + + free(htxt.s); + hts_close(fp_out); + hts_close(fp); + bcf_hdr_destroy(hdr_out); + bcf_hdr_destroy(hdr); +} + + +static void usage(args_t *args) +{ + fprintf(stderr, "\n"); + fprintf(stderr, "About: Modify header of VCF/BCF files, change sample names.\n"); + fprintf(stderr, "Usage: bcftools reheader [OPTIONS] \n"); + fprintf(stderr, "\n"); + fprintf(stderr, "Options:\n"); + fprintf(stderr, " -h, --header new header\n"); + fprintf(stderr, " -o, --output write output to a file [standard output]\n"); + fprintf(stderr, " -s, --samples new sample names\n"); + fprintf(stderr, "\n"); + exit(1); +} + +int main_reheader(int argc, char *argv[]) +{ + int c; + args_t *args = (args_t*) calloc(1,sizeof(args_t)); + args->argc = argc; args->argv = argv; + + static struct option loptions[] = + { + {"output",1,0,'o'}, + {"header",1,0,'h'}, + {"samples",1,0,'s'}, + {0,0,0,0} + }; + while ((c = getopt_long(argc, argv, "s:h:o:",loptions,NULL)) >= 0) + { + switch (c) + { + case 'o': args->output_fname = optarg; break; + case 's': args->samples_fname = optarg; break; + case 'h': args->header_fname = optarg; break; + case '?': usage(args); + default: error("Unknown argument: %s\n", optarg); + } + } + + if ( optind>=argc ) + { + if ( !isatty(fileno((FILE *)stdin)) ) args->fname = "-"; // reading from stdin + else usage(args); + } + else args->fname = argv[optind]; + + if ( !args->samples_fname && !args->header_fname ) usage(args); + if ( !args->fname ) usage(args); + + args->fp = hts_open(args->fname,"r"); + if ( !args->fp ) error("Failed to open: %s\n", args->fname); + args->type = *hts_get_format(args->fp); + + if ( args->type.format==vcf ) + { + if ( args->type.compression==bgzf || args->type.compression==gzip ) + reheader_vcf_gz(args); + else + reheader_vcf(args); + } + else + reheader_bcf(args, args->type.compression==bgzf || args->type.compression==gzip); + + free(args); + return 0; +} diff --git a/smpl_ilist.c b/smpl_ilist.c new file mode 100644 index 0000000..c7fa913 --- /dev/null +++ b/smpl_ilist.c @@ -0,0 +1,106 @@ +/* + Copyright (C) 2016 Genome Research Ltd. + + Author: Petr Danecek + + Permission is hereby granted, free of charge, to any person obtaining a copy + of this software and associated documentation files (the "Software"), to deal + in the Software without restriction, including without limitation the rights + to use, copy, modify, merge, publish, distribute, sublicense, and/or sell + copies of the Software, and to permit persons to whom the Software is + furnished to do so, subject to the following conditions: + + The above copyright notice and this permission notice shall be included in + all copies or substantial portions of the Software. + + THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR + IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, + FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE + AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER + LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, + OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN + THE SOFTWARE. +*/ + +#include "bcftools.h" +#include "smpl_ilist.h" + +void smpl_ilist_destroy(smpl_ilist_t *smpl) +{ + free(smpl->idx); + free(smpl); +} + +smpl_ilist_t *smpl_ilist_init(bcf_hdr_t *hdr, char *sample_list, int is_file, int flags) +{ + smpl_ilist_t *smpl = (smpl_ilist_t*) calloc(1,sizeof(smpl_ilist_t)); + + int i; + if ( !sample_list ) + { + smpl->n = bcf_hdr_nsamples(hdr); + smpl->idx = (int*) malloc(sizeof(int)*smpl->n); + for (i=0; in; i++) smpl->idx[i] = i; + return smpl; + } + + int nlist; + char **list = hts_readlist(sample_list[0]=='^'?sample_list+1:sample_list, is_file, &nlist); + if ( !list ) error("Could not parse %s\n", sample_list); + + // preserve the VCF order + int *tmp = (int*)calloc(bcf_hdr_nsamples(hdr),sizeof(int)); + for (i=0; i=0 ) + { + tmp[idx] = 1; + smpl->n++; + } + else if ( flags&SMPL_STRICT ) + error("No such sample: %s\n", list[i]); + } + + if ( sample_list[0]=='^' ) smpl->n = bcf_hdr_nsamples(hdr) - smpl->n; + smpl->idx = (int*) malloc(sizeof(int)*smpl->n); + + int j = 0; + if ( sample_list[0]!='^' ) + { + for (i=0; iidx[j++] = i; + } + else + { + for (i=0; iidx[j++] = i; + } + + free(tmp); + for (i=0; in = bcf_hdr_nsamples(hdr_a); + smpl->idx = (int*) malloc(sizeof(int)*smpl->n); + for (i=0; in; i++) + { + const char *name = bcf_hdr_int2id(hdr_a, BCF_DT_SAMPLE, i); + smpl->idx[i] = bcf_hdr_id2int(hdr_b, BCF_DT_SAMPLE, name); + if ( flags&SMPL_STRICT && smpl->idx[i]<0 ) + error("The sample %s is not present in the second file\n", name); + } + return smpl; +} + diff --git a/smpl_ilist.h b/smpl_ilist.h new file mode 100644 index 0000000..7083cf2 --- /dev/null +++ b/smpl_ilist.h @@ -0,0 +1,47 @@ +/* + Copyright (C) 2016 Genome Research Ltd. + + Author: Petr Danecek + + Permission is hereby granted, free of charge, to any person obtaining a copy + of this software and associated documentation files (the "Software"), to deal + in the Software without restriction, including without limitation the rights + to use, copy, modify, merge, publish, distribute, sublicense, and/or sell + copies of the Software, and to permit persons to whom the Software is + furnished to do so, subject to the following conditions: + + The above copyright notice and this permission notice shall be included in + all copies or substantial portions of the Software. + + THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR + IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, + FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE + AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER + LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, + OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN + THE SOFTWARE. +*/ +/* + Parse --samples and --samples-file +*/ + +#ifndef __SMPL_ILIST_H__ +#define __SMPL_ILIST_H__ + +#include + +#define SMPL_NONE 0 // flexible error recovery +#define SMPL_STRICT 1 // samples must exist + +typedef struct +{ + int *idx; // index to bcf_hdr_t.samples + int n; +} +smpl_ilist_t; + +smpl_ilist_t *smpl_ilist_init(bcf_hdr_t *hdr, char *sample_list, int is_file, int flags); +smpl_ilist_t *smpl_ilist_map(bcf_hdr_t *hdr_a, bcf_hdr_t *hdr_b, int flags); +void smpl_ilist_destroy(smpl_ilist_t *smpl); + +#endif diff --git a/tabix.c b/tabix.c new file mode 100644 index 0000000..c1874c2 --- /dev/null +++ b/tabix.c @@ -0,0 +1,131 @@ +/* tabix.c -- tabix subcommand. + + Copyright (C) 2012 Broad Institute. + Copyright (C) 2013, 2016 Genome Research Ltd. + + Author: Heng Li + +Permission is hereby granted, free of charge, to any person obtaining a copy +of this software and associated documentation files (the "Software"), to deal +in the Software without restriction, including without limitation the rights +to use, copy, modify, merge, publish, distribute, sublicense, and/or sell +copies of the Software, and to permit persons to whom the Software is +furnished to do so, subject to the following conditions: + +The above copyright notice and this permission notice shall be included in +all copies or substantial portions of the Software. + +THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE +AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER +LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, +OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN +THE SOFTWARE. */ + +#include +#include +#include +#include +#include +#include + +int main_tabix(int argc, char *argv[]) +{ + int c, min_shift = -1, is_force = 0, is_all = 0, detect = 1; + tbx_conf_t conf = tbx_conf_gff; + while ((c = getopt(argc, argv, "0fap:s:b:e:S:c:m:")) >= 0) + if (c == '0') conf.preset |= TBX_UCSC; + else if (c == 'f') is_force = 1; + else if (c == 'a') is_all = 1; + else if (c == 'm') min_shift = atoi(optarg); + else if (c == 's') conf.sc = atoi(optarg); + else if (c == 'b') conf.bc = atoi(optarg); + else if (c == 'e') conf.ec = atoi(optarg); + else if (c == 'c') conf.meta_char = *optarg; + else if (c == 'S') conf.line_skip = atoi(optarg); + else if (c == 'p') { + if (strcmp(optarg, "gff") == 0) conf = tbx_conf_gff; + else if (strcmp(optarg, "bed") == 0) conf = tbx_conf_bed; + else if (strcmp(optarg, "sam") == 0) conf = tbx_conf_sam; + else if (strcmp(optarg, "vcf") == 0) conf = tbx_conf_vcf; + else { + fprintf(stderr, "The type '%s' not recognised\n", optarg); + return 1; + detect = 0; + } + + } + if (optind == argc) { + fprintf(stderr, "\nUsage: bcftools tabix [options] [reg1 [...]]\n\n"); + fprintf(stderr, "Options: -p STR preset: gff, bed, sam or vcf [gff]\n"); + fprintf(stderr, " -s INT column number for sequence names (suppressed by -p) [1]\n"); + fprintf(stderr, " -b INT column number for region start [4]\n"); + fprintf(stderr, " -e INT column number for region end (if no end, set INT to -b) [5]\n"); + fprintf(stderr, " -0 specify coordinates are zero-based\n"); + fprintf(stderr, " -S INT skip first INT lines [0]\n"); + fprintf(stderr, " -c CHAR skip lines starting with CHAR [null]\n"); + fprintf(stderr, " -a print all records\n"); + fprintf(stderr, " -f force to overwrite existing index\n"); + fprintf(stderr, " -m INT set the minimal interval size to 1<= 0) puts(s.s); + bgzf_close(fp); + free(s.s); + } else if (optind + 2 > argc) { // create index + if ( detect ) + { + // auto-detect file type by file name + int l = strlen(argv[optind]); + int strcasecmp(const char *s1, const char *s2); + if (l>=7 && strcasecmp(argv[optind]+l-7, ".gff.gz") == 0) conf = tbx_conf_gff; + else if (l>=7 && strcasecmp(argv[optind]+l-7, ".bed.gz") == 0) conf = tbx_conf_bed; + else if (l>=7 && strcasecmp(argv[optind]+l-7, ".sam.gz") == 0) conf = tbx_conf_sam; + else if (l>=7 && strcasecmp(argv[optind]+l-7, ".vcf.gz") == 0) conf = tbx_conf_vcf; + } + + if (!is_force) { + char *fn; + FILE *fp; + fn = (char*)malloc(strlen(argv[optind]) + 5); + strcat(strcpy(fn, argv[optind]), min_shift <= 0? ".tbi" : ".csi"); + if ((fp = fopen(fn, "rb")) != 0) { + fclose(fp); + free(fn); + fprintf(stderr, "[E::%s] the index file exists; use option '-f' to overwrite\n", __func__); + return 1; + } + free(fn); + } + if ( tbx_index_build(argv[optind], min_shift, &conf) ) + { + fprintf(stderr,"tbx_index_build failed: Is the file bgzip-compressed? Was wrong -p [type] option used?\n"); + return 1; + } + } else { // read with random access + tbx_t *tbx; + BGZF *fp; + kstring_t s; + int i; + if ((tbx = tbx_index_load(argv[optind])) == 0) return 1; + if ((fp = bgzf_open(argv[optind], "r")) == 0) return 1; + s.s = 0; s.l = s.m = 0; + for (i = optind + 1; i < argc; ++i) { + hts_itr_t *itr; + if ((itr = tbx_itr_querys(tbx, argv[i])) == 0) continue; + while (tbx_bgzf_itr_next(fp, tbx, itr, &s) >= 0) puts(s.s); + tbx_itr_destroy(itr); + } + free(s.s); + bgzf_close(fp); + tbx_destroy(tbx); + } + return 0; +} diff --git a/test/23andme.fa b/test/23andme.fa new file mode 100644 index 0000000..8a917f6 --- /dev/null +++ b/test/23andme.fa @@ -0,0 +1,14 @@ +>1 +CACGTNACGGCTGAAGTCCAAGGTAC +CGTATCGAGTTCACAGTCGATAGCTC +GATCGATAGCATCGCTAGCNNNACTA +CGATCGATCGCTCTCCGTAACACTCA +AAAACGATCGATCGACTGCTCTTTAG +CGATGACTTTAGGGGAAAAA +>2 +CGCTCAGCCGTACAGCCGAGCAGGAC +ACGCTATTTTAGATCGACTGGCTNNG +CGCTAGCTACGCTTTAGCACGAGAA +>Y +NNNGCATACGTGTCCATCACGATGAT +AGCGATGATCGATC diff --git a/test/23andme.fa.fai b/test/23andme.fa.fai new file mode 100644 index 0000000..6489fa3 --- /dev/null +++ b/test/23andme.fa.fai @@ -0,0 +1,3 @@ +1 150 3 26 27 +2 77 162 26 27 +Y 40 245 26 27 diff --git a/test/aa.fa b/test/aa.fa new file mode 100644 index 0000000..f54b206 --- /dev/null +++ b/test/aa.fa @@ -0,0 +1,29 @@ +>20 +AGGATGGGGCTCATTAATAGAGCTCCACTTGTCTCCAGAATCACTGGTGAGGAAGGGGAG +TGTTGCCCCCACATTcGTGCACATCAGGGATGGTTCACCGAACTCCACACCAGTCTCTGc +AGAGCCTGTTGGGGAGAGGAGGGCTGTGGCTTCTTTGATGGTGTTCACCTGGAGTAGAGC +AAGTATTGTCAAAAGGGTCATCCTCGGAGGTTGCAGTGAGCCGAGATCGCACCATTGCAC +TGCAGCCTGGGAGACAGAGCAAGACTCCATCTCAAAAAaAAAaAaAAAaAAAAAGGCCAT +C +>1 +............................................................ +............................................................ +............................................................ +............................................................ +............................................................ +. +>2 2:1382388-1382602 +AGCACCTGCCTCCAGGGCGACTGCGACTCCGTGCTGCTCTCCCTGGGAGGCCCTGTTCCT +GTCCAtGTGGCCCGTGCTGGTGTGACAGTGGGAGGACAGAGATCTGTgGGAATGCCGTGC +ACCCGGCAGATGCTGTGTGCACCTGGCGGGgGGTTCgTgCCTGAGCTGCTGTAGgGTGAA +GCTGCAGTTTCAGAAGGTCCGAGAGATGTTAAACC +>3 +ACTGGACACGTGGACACACACACACACACACACACACACACAGTCAAACCACCTACCAGA +>4 +TCCCCTCTTGACCTCcCTCTATTTTTT..TTTTTTTCTGAGATGGATTTTTGCTCTTGTT +>5 +GTCTCAAAAAAAAAAAAAAAAAAAAGAAAAG +>21 +TTTATTATtAGTAttaTTAAATTGAATTTATTTAGTGTACATACATTCATGTGTATTGTG +>22 +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNN diff --git a/test/aa.fa.fai b/test/aa.fa.fai new file mode 100644 index 0000000..b718af4 --- /dev/null +++ b/test/aa.fa.fai @@ -0,0 +1,8 @@ +20 301 4 60 61 +1 301 314 60 61 +2 215 642 60 61 +3 60 864 60 61 +4 60 928 60 61 +5 31 992 31 32 +21 60 1028 60 61 +22 30 1093 30 31 diff --git a/test/aa.hdr b/test/aa.hdr new file mode 100644 index 0000000..3f2b84a --- /dev/null +++ b/test/aa.hdr @@ -0,0 +1 @@ +##INFO= diff --git a/test/aa.out b/test/aa.out new file mode 100644 index 0000000..c08f4c1 --- /dev/null +++ b/test/aa.out @@ -0,0 +1,31 @@ +##fileformat=VCFv4.2 +##FILTER= +##contig= +##contig= +##contig= +##contig= +##contig= +##contig= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO +1 105 . TAAACCCTA T,TAACCCTA 999 PASS . +2 1 . GGGCGTCTCATAGCTGGAGCAATGGCGAGCGCCTGGACAAGGGAGGGGAAGGGGTTCTTATTACTGACGCGGGTAGCCCCTACTGCTGTGTGGTTCCCCTATTTTTTTTTTTTTCTTTTTGAGACGGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGCACAATCTCGGCTCACTGCAAGCTCCACC ACG 999 PASS . +2 101 . A ATT 999 PASS . +2 114 . T TTC,TT 999 PASS . +2 115 . C T 999 PASS AA=C +20 3 . G CT 999 PASS . +20 5 . TG CT 999 PASS . +20 5 . TGGG TAC,TG,TGGGG,AC . PASS . +20 59 . AG . 999 PASS . +20 81 . A C 999 PASS AA=A +20 84 . G T 999 PASS AA=T +20 95 . T A 999 PASS AA=T +20 95 . TCACCG AAAAAA 999 PASS . +20 273 . C CAA,CAAA 999 PASS . +20 273 . C CAAAAAAAAAA 999 PASS . +20 273 . C CAA 999 PASS . +20 275 . A C,G 999 PASS AA=A +3 10 . GTGGAC GTGGACACAC,GTGGACAC,GTGGACACACAC,GTGG,GTGGACACACACAC,ATGGACACACAC 999 PASS . +3 17 . CA C 999 PASS . +4 36 . TC C,TT,TTC 999 PASS . +5 21 . A AAG 999 PASS . diff --git a/test/aa.vcf b/test/aa.vcf new file mode 100644 index 0000000..7bee378 --- /dev/null +++ b/test/aa.vcf @@ -0,0 +1,30 @@ +##fileformat=VCFv4.2 +##FILTER= +##contig= +##contig= +##contig= +##contig= +##contig= +##contig= +#CHROM POS ID REF ALT QUAL FILTER INFO +1 105 . TAAACCCTA T,TAACCCTA 999 PASS . +2 1 . GGGCGTCTCATAGCTGGAGCAATGGCGAGCGCCTGGACAAGGGAGGGGAAGGGGTTCTTATTACTGACGCGGGTAGCCCCTACTGCTGTGTGGTTCCCCTATTTTTTTTTTTTTCTTTTTGAGACGGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGCACAATCTCGGCTCACTGCAAGCTCCACC ACG 999 PASS . +2 101 . A ATT 999 PASS . +2 114 . T TTC,TT 999 PASS . +2 115 . C T 999 PASS . +20 3 . G CT 999 PASS . +20 5 . TG CT 999 PASS . +20 5 . TGGG TAC,TG,TGGGG,AC . PASS . +20 59 . AG . 999 PASS . +20 81 . A C 999 PASS . +20 84 . G T 999 PASS . +20 95 . T A 999 PASS . +20 95 . TCACCG AAAAAA 999 PASS . +20 273 . C CAA,CAAA 999 PASS . +20 273 . C CAAAAAAAAAA 999 PASS . +20 273 . C CAA 999 PASS . +20 275 . A C,G 999 PASS . +3 10 . GTGGAC GTGGACACAC,GTGGACAC,GTGGACACACAC,GTGG,GTGGACACACACAC,ATGGACACACAC 999 PASS . +3 17 . CA C 999 PASS . +4 36 . TC C,TT,TTC 999 PASS . +5 21 . A AAG 999 PASS . diff --git a/test/ad-bias.out b/test/ad-bias.out new file mode 100644 index 0000000..c268572 --- /dev/null +++ b/test/ad-bias.out @@ -0,0 +1,25 @@ +# +# FT, Fisher Test [2]Sample [3]Control [4]Chrom [5]Pos [6]smpl.nREF [7]smpl.nALT [8]ctrl.nREF [9]ctrl.nALT [10]P-value +FT NA12890 NA12892 22 16051249 4 3 55 0 9.254363e-04 +FT NA12890 NA12892 22 16051347 2 4 43 0 7.079613e-05 +FT NA12890 NA12891 22 16051453 5 4 39 0 6.475486e-04 +FT NA12890 NA12892 22 16051453 5 4 47 0 3.430532e-04 +FT NA12890 NA12892 22 16051497 0 8 44 0 1.328836e-09 +FT NA12890 NA12892 22 16053659 0 9 30 0 4.718870e-09 +FT NA12890 NA12892 22 16053791 4 4 32 0 7.659481e-04 +FT NA12890 NA12892 22 16055942 0 7 31 0 7.923770e-08 +FT NA12890 NA12892 22 16056126 2 6 27 0 1.725030e-05 +FT NA12890 NA12891 22 16058415 9 0 0 37 9.076747e-10 +FT NA12890 NA12891 22 16058463 1 8 40 0 1.995662e-08 +FT NA12890 NA12892 22 16058463 1 8 45 0 8.649972e-09 +FT NA12890 NA12891 22 16058758 2 8 19 0 1.048427e-05 +FT NA12890 NA12892 22 16058758 2 8 34 0 2.539036e-07 +FT NA12890 NA12891 22 16058766 11 0 0 4 7.326007e-04 +FT NA12890 NA12892 22 16058852 0 3 36 0 1.094212e-04 +FT NA12890 NA12891 22 16059081 6 0 0 35 2.224007e-07 +FT NA12890 NA12891 22 16059734 1 9 23 0 2.592884e-07 +FT NA12890 NA12892 22 16059734 1 9 31 0 2.854341e-08 +FT NA12890 NA12891 22 16059753 9 0 0 19 1.447828e-07 +FT NA12890 NA12891 22 16060178 5 0 1 20 9.121313e-05 +# SN, Summary Numbers [2]Number of Pairs [3]Number of Sites [4]Number of comparisons [5]P-value output threshold +SN 2 36 55 1.000000e-03 diff --git a/test/ad-bias.samples b/test/ad-bias.samples new file mode 100644 index 0000000..426bad0 --- /dev/null +++ b/test/ad-bias.samples @@ -0,0 +1,2 @@ +NA12890 NA12891 +NA12890 NA12892 diff --git a/test/ad-bias.vcf b/test/ad-bias.vcf new file mode 100644 index 0000000..e14231b --- /dev/null +++ b/test/ad-bias.vcf @@ -0,0 +1,42 @@ +##fileformat=VCFv4.2 +##FILTER= +##contig= +##FORMAT= +##FORMAT= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA12890 NA12891 NA12892 +22 16050159 . C T 68 . . GT:AD 0/0:4,0 0/1:6,8 0/0:26,0 +22 16050252 . A T 85 . . GT:AD 0/0:3,0 0/1:13,13 0/0:40,0 +22 16051249 . T C 32.1761 . . GT:AD 0/1:4,3 0/0:41,0 0/0:55,0 +22 16051347 . G C 283 . . GT:AD 1/1:2,4 0/1:20,20 0/0:43,0 +22 16051453 . A C 3.42882 . . GT:AD 0/1:5,4 0/0:39,0 0/0:47,0 +22 16051497 . A G 362 . . GT:AD 1/1:0,8 0/1:14,20 0/0:44,0 +22 16051968 . C A 136 . . GT:AD 0/0:4,0 0/1:11,11 0/0:13,0 +22 16052167 . AAAACAAACAAACAAACAAACAAACAAACAAAC AAAACAAACAAACAAACAAACAAACAAACAAACAAACAAAC 217 . . GT:AD ./.:0,0 1/1:0,27 0/0:46,0 +22 16052169 . AACAAACA AACAAACAGACAAACA 241 . . GT:AD 0/1:1,1 0/1:7,29 0/0:54,0 +22 16052180 . AAAC AAACCAACTAAC 221 . . GT:AD 0/0:2,0 0/1:16,15 0/0:55,0 +22 16052239 . A G 172 . . GT:AD 0/0:5,0 0/1:12,17 0/0:44,0 +22 16052513 . G C 153 . . GT:AD 0/0:11,0 0/1:25,16 0/0:38,0 +22 16052618 . G A 124 . . GT:AD 0/0:7,0 0/1:29,12 0/0:41,0 +22 16053659 . A C 352 . . GT:AD 1/1:0,9 1/1:0,21 0/0:30,0 +22 16053791 . C A 287 . . GT:AD 0/1:4,4 0/1:13,16 0/0:32,0 +22 16054454 . C T 14.2772 . . GT:AD 0/1:2,2 0/0:34,0 0/0:31,0 +22 16054667 . C G 179 . . GT:AD 0/0:8,0 0/1:12,15 0/0:27,0 +22 16054740 . A G 126 . . GT:AD 0/0:6,0 0/1:11,16 0/0:26,0 +22 16055942 . C T 385 . . GT:AD 1/1:0,7 1/1:0,22 0/0:31,0 +22 16056126 . G A 263 . . GT:AD 0/1:2,6 0/1:12,16 0/0:27,0 +22 16056854 . G GA 17.3105 . . GT:AD 0/0:7,0 0/1:11,15 0/0:35,0 +22 16057248 . G A 167 . . GT:AD 0/0:5,0 0/1:15,14 0/0:32,0 +22 16057320 . G A 20.0168 . . GT:AD 0/1:2,2 0/0:25,0 0/0:36,0 +22 16057417 . C T 16.3704 . . GT:AD 0/1:2,2 0/0:36,0 0/0:25,0 +22 16058070 . A G 452 . . GT:AD 1/1:0,4 1/1:0,21 1/1:0,22 +22 16058415 . A G 212 . . GT:AD 0/0:9,0 1/1:0,37 0/0:35,2 +22 16058463 . C T 136 . . GT:AD 0/1:1,8 0/0:40,0 0/0:45,0 +22 16058758 . C A 107 . . GT:AD 1/1:2,8 0/0:19,0 0/0:34,0 +22 16058766 . G A 15.517 . . GT:AD 0/0:11,0 1/1:0,4 0/0:32,0 +22 16058852 . A T 198 . . GT:AD 1/1:0,3 1/1:0,19 0/0:36,0 +22 16058883 . A G 129 . . GT:AD 1/1:0,1 1/1:0,18 0/0:36,0 +22 16059081 . A G 212 . . GT:AD 0/0:6,0 1/1:0,35 0/0:35,0 +22 16059734 . C T 114 . . GT:AD 1/1:1,9 0/0:23,0 0/0:31,0 +22 16059753 . A T 212 . . GT:AD 0/0:9,0 1/1:0,19 0/0:28,0 +22 16059973 . C A 195 . . GT:AD 0/0:4,0 0/0:21,0 0/1:21,18 +22 16060178 . G A 187 . . GT:AD 0/0:5,0 1/1:1,20 0/0:36,0 diff --git a/test/af-dist.out b/test/af-dist.out new file mode 100644 index 0000000..044659d --- /dev/null +++ b/test/af-dist.out @@ -0,0 +1,23 @@ +# +# PROB_DIST, genotype probability distribution, assumes HWE +PROB_DIST 0.000000 0.100000 0 +PROB_DIST 0.100000 0.200000 0 +PROB_DIST 0.200000 0.300000 1 +PROB_DIST 0.300000 0.400000 0 +PROB_DIST 0.400000 0.500000 14 +PROB_DIST 0.500000 0.600000 2 +PROB_DIST 0.600000 0.700000 2 +PROB_DIST 0.700000 0.800000 0 +PROB_DIST 0.800000 0.900000 0 +PROB_DIST 0.900000 1.000000 0 +# DEV_DIST, distribution of AF deviation, based on AF and INFO/AN, AC calculated on the fly +DEV_DIST 0.000000 0.100000 7 +DEV_DIST 0.100000 0.200000 0 +DEV_DIST 0.200000 0.300000 0 +DEV_DIST 0.300000 0.400000 0 +DEV_DIST 0.400000 0.500000 0 +DEV_DIST 0.500000 0.600000 0 +DEV_DIST 0.600000 0.700000 0 +DEV_DIST 0.700000 0.800000 0 +DEV_DIST 0.800000 0.900000 0 +DEV_DIST 0.900000 1.000000 0 diff --git a/test/af-dist.vcf b/test/af-dist.vcf new file mode 100644 index 0000000..e1e7af3 --- /dev/null +++ b/test/af-dist.vcf @@ -0,0 +1,19 @@ +##fileformat=VCFv4.1 +##FILTER= +##reference=file:///seq/references/1000Genomes-NCBI37.fasta +##contig= +##contig= +##FORMAT= +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA00001 NA00002 NA00003 +11 2343543 . A . 999 . AN=6 GT 0/0 0/0 0/0 +11 5464562 . C T 999 . AN=0;AC=0 GT ./. ./. ./. +20 76962 rs6111385 T C 999 . AN=6;AF=0.833333;AC=5 GT 0/1 1/1 1/1 +20 126310 . ACC A 999 . AN=6;AF=0.666667;AC=4 GT 0/1 0/1 1/1 +20 138125 rs2298108 G T 999 . AN=6;AF=0.666667;AC=4 GT 0/1 0/1 1/1 +20 138148 rs2298109 C T 999 . AN=6;AF=0.666667;AC=4 GT 0/1 0/1 1/1 +20 271225 . T TTTA,TA 999 . AN=6;AF=0.333333,0.333333;AC=2,2 GT 0/2 0/1 1/2 +20 304568 . C T 999 . AN=6;AF=0.666667;AC=4 GT 0|1 0|1 1|1 +20 326891 . A AC 999 . AN=4;AF=0.5;AC=2 GT 0|1 0|1 ./. diff --git a/test/annotate.hdr b/test/annotate.hdr new file mode 100644 index 0000000..c2cbf73 --- /dev/null +++ b/test/annotate.hdr @@ -0,0 +1,4 @@ +##INFO= +##INFO= +##INFO= +##INFO= diff --git a/test/annotate.out b/test/annotate.out new file mode 100644 index 0000000..582318e --- /dev/null +++ b/test/annotate.out @@ -0,0 +1,43 @@ +##fileformat=VCFv4.1 +##FILTER= +##INFO= +##FORMAT= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FILTER= +##FILTER= +##contig= +##contig= +##contig= +##contig= +##test= +##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta +##readme=AAAAAA +##readme=BBBBBB +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B +1 3000150 snp_3000150 C T 999 PASS AN=4;AC=2;T_INT=1,2;T_FLOAT=1e-10,2e-10 GT:GQ 0/1:245 0/1:245 +1 3000151 snp_3000151 C T 999 PASS AN=4;AC=2;T_INT=1;T_FLOAT=2e-10 GT:DP:GQ 0/1:32:245 0/1:32:245 +1 3062915 indel_3062915 GTTT G 12.9 q10 DP4=1,2,3,4;AN=4;AC=2;INDEL;STR=test GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 0/1:409:35:-20,-5,-20 +1 3062915 snp_3062915 G T,C 999 test TEST=5;DP4=1,2,3,4;AN=3;AC=1,1;T_INT=1;T_FLOAT=2e-10 GT:TT:GQ:DP:GL 0/1:0,1:409:35:-20,-5,-20,-20,-5,-20 2:0,1:409:35:-20,-5,-20 +1 3106154 indel_3106154 CAAA C 342 PASS AN=4;AC=2;INDEL GT:GQ:DP 0/1:245:32 0/1:245:32 +1 3106154 indel_3106154 C CT 59.2 PASS AN=4;AC=2;INDEL GT:GQ:DP 0/1:245:32 0/1:245:32 +1 3157410 indel_3157410 GA G 90.6 q10 AN=4;AC=4;INDEL GT:GQ:DP 1/1:21:21 1/1:21:21 +1 3162006 indel_3162006 GAA G 60.2 PASS AN=4;AC=2;INDEL GT:GQ:DP 0/1:212:22 0/1:212:22 +1 3177144 snp_3177144 G T 999 PASS AN=4;AC=2;T_INT=1;T_FLOAT=2e-10 GT:GQ:DP 0/0:150:30 1/1:150:30 +1 3177144 ref_3177144 G . 999 PASS AN=4;AC=0;T_INT=1;T_FLOAT=2e-10 GT:GQ:DP 0/0:150:30 0/0:150:30 +1 3184885 indel_3184885 TAAAA TA,T 61.5 PASS AN=4;AC=2,2;INDEL GT:GQ:DP 1/2:12:10 1/2:12:10 +2 3199812 indel_3199812 G GTT,GT 82.7 PASS AN=4;AC=2,2;INDEL GT:GQ:DP 1/2:322:26 1/2:322:26 +3 3212016 indel_3212016 CTT C,CT 79 PASS AN=4;AC=2,2;INDEL GT:GQ:DP 1/2:91:26 1/2:91:26 +4 3258448 indel_3258448 TACACACAC T 59.9 PASS AN=4;AC=2;INDEL GT:GQ:DP 0/1:325:31 0/1:325:31 +4 4000000 id1 T A,C 59.9 PASS AN=4;AC=2;INDEL GT:GQ:DP 0/1:325:31 0/1:325:31 +4 4000001 id2 T A 59.9 PASS AN=4;AC=2;INDEL GT:GQ:DP 0/1:325:31 0/1:325:31 diff --git a/test/annotate.tab b/test/annotate.tab new file mode 100644 index 0000000..1fc5582 --- /dev/null +++ b/test/annotate.tab @@ -0,0 +1,18 @@ +3 3212016 CTT C,CT indel_3212016 . . . 1 +4 3258448 TACACACAC T indel_3258448 . . . 1 +4 4000000 T C id1 . . . 1 +4 4000001 T C,A id2 . . . 1 +2 3199812 G GTT,GT indel_3199812 . . . 1 +1 3000150 C CT indel_3000150 . . . 1 +1 3000150 C T snp_3000150 999 1,2 1e-10,2e-10 . +1 3000151 C T snp_3000151 999 1 2e-10 . +1 3062915 G T,C snp_3062915 999 1 2e-10 . +1 3062915 GTTT G indel_3062915 . . . 1 +1 3106154 A C snp_3106154 999 1 2e-10 . +1 3106154 C CT indel_3106154 . . . 1 +1 3106154 CAAA C indel_3106154 . . . 1 +1 3157410 GA G indel_3157410 . . . 1 +1 3162006 GAA G indel_3162006 . . . 1 +1 3177144 G . ref_3177144 999 1 2e-10 . +1 3177144 G T snp_3177144 999 1 2e-10 0 +1 3184885 TAAAA TA,T indel_3184885 . . . 1 diff --git a/test/annotate.vcf b/test/annotate.vcf new file mode 100644 index 0000000..e85bc11 --- /dev/null +++ b/test/annotate.vcf @@ -0,0 +1,39 @@ +##fileformat=VCFv4.1 +##INFO= +##FORMAT= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FILTER= +##FILTER= +##contig= +##contig= +##contig= +##contig= +##test= +##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta +##readme=AAAAAA +##readme=BBBBBB +##INFO= +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B +1 3000150 . C T 59.2 PASS AN=4;AC=2 GT:GQ 0/1:245 0/1:245 +1 3000151 . C T 59.2 PASS AN=4;AC=2 GT:DP:GQ 0/1:32:245 0/1:32:245 +1 3062915 id3D GTTT G 12.9 q10 DP4=1,2,3,4;AN=4;AC=2;INDEL;STR=test GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 0/1:409:35:-20,-5,-20 +1 3062915 idSNP G T,C 12.6 test TEST=5;DP4=1,2,3,4;AN=3;AC=1,1 GT:TT:GQ:DP:GL 0/1:0,1:409:35:-20,-5,-20,-20,-5,-20 2:0,1:409:35:-20,-5,-20 +1 3106154 . CAAA C 342 PASS AN=4;AC=2 GT:GQ:DP 0/1:245:32 0/1:245:32 +1 3106154 . C CT 59.2 PASS AN=4;AC=2 GT:GQ:DP 0/1:245:32 0/1:245:32 +1 3157410 . GA G 90.6 q10 AN=4;AC=4 GT:GQ:DP 1/1:21:21 1/1:21:21 +1 3162006 . GAA G 60.2 PASS AN=4;AC=2 GT:GQ:DP 0/1:212:22 0/1:212:22 +1 3177144 . G T 45 PASS AN=4;AC=2 GT:GQ:DP 0/0:150:30 1/1:150:30 +1 3177144 . G . 45 PASS AN=4;AC=0 GT:GQ:DP 0/0:150:30 0/0:150:30 +1 3184885 . TAAAA TA,T 61.5 PASS AN=4;AC=2,2 GT:GQ:DP 1/2:12:10 1/2:12:10 +2 3199812 . G GTT,GT 82.7 PASS AN=4;AC=2,2 GT:GQ:DP 1/2:322:26 1/2:322:26 +3 3212016 . CTT C,CT 79 PASS AN=4;AC=2,2 GT:GQ:DP 1/2:91:26 1/2:91:26 +4 3258448 . TACACACAC T 59.9 PASS AN=4;AC=2 GT:GQ:DP 0/1:325:31 0/1:325:31 +4 4000000 . T A,C 59.9 PASS AN=4;AC=2 GT:GQ:DP 0/1:325:31 0/1:325:31 +4 4000001 . T A 59.9 PASS AN=4;AC=2 GT:GQ:DP 0/1:325:31 0/1:325:31 diff --git a/test/annotate10.hdr b/test/annotate10.hdr new file mode 100644 index 0000000..2162e9d --- /dev/null +++ b/test/annotate10.hdr @@ -0,0 +1,3 @@ +##FORMAT= +##FORMAT= +##FORMAT= diff --git a/test/annotate10.out b/test/annotate10.out new file mode 100644 index 0000000..c7f393b --- /dev/null +++ b/test/annotate10.out @@ -0,0 +1,18 @@ +##fileformat=VCFv4.1 +##FILTER= +##FILTER= +##contig= +##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta +##INFO= +##INFO= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT B A +1 3000001 . C T . . . 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GT . . +1 3000002 id C T 99 q99 FLAG;IINT=88,99;IFLT=8.8,9.9;ISTR=888,999 GT 1|1 0|1 +1 3000003 id C T 99 q99 FLAG;IINT=88,99;IFLT=8.8,9.9;ISTR=888,999 GT 1|1 0|1 +1 3000004 id C T 99 q99 FLAG;IINT=88,99;IFLT=8.8,9.9;ISTR=888,999 GT 1|1 0|1 diff --git a/test/annotate11.out b/test/annotate11.out new file mode 100644 index 0000000..895f5b0 --- /dev/null +++ b/test/annotate11.out @@ -0,0 +1,18 @@ +##fileformat=VCFv4.1 +##FILTER= +##contig= +##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta +##INFO= +##INFO= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FILTER= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B C +1 3000001 xx C T 11 PASS FLAG;IINT=11;IFLT=1.1;ISTR=xxx GT:FINT:FFLT:FSTR 0/0:11:1.1:xxx 0/0:11:1.1:x 0/0:11:1.1:x +1 3000002 . C T . . . GT:FINT:FFLT:FSTR .:77:7.7:77 .:.:.:. .:.:.:. +1 3000003 xx C T 11 q11 FLAG;IINT=.;IFLT=.;ISTR=. GT:FINT:FFLT:FSTR 0/0:77:7.7:77 0/0:.:.:. 0/0:.:.:. +1 3000004 xx C T 11 q11 FLAG;IINT=11;IFLT=1.1;ISTR=xxx GT:FINT:FFLT:FSTR 0/0:77:7.7:77 0/0:11:1.1:xxx 0/0:11:1.1:xxx diff --git a/test/annotate12.out b/test/annotate12.out new file mode 100644 index 0000000..4fca304 --- /dev/null +++ b/test/annotate12.out @@ -0,0 +1,20 @@ +##fileformat=VCFv4.1 +##FILTER= +##contig= +##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta +##INFO= +##INFO= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FILTER= +##INFO= +##FORMAT= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B C +1 3000001 xx C T 11 PASS FLAG;IINT=11;IFLT=1.1;ISTR=xxx GT:FINT:FFLT:FSTR 0/0:11:1.1:xxx 0/0:11:1.1:x 0/0:11:1.1:x +1 3000002 . C T . . 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CAAA C 342 PASS AN=4;AC=2 GT:GQ:DP 0/1:245:32 0/1:245:32 diff --git a/test/annots.vcf b/test/annots.vcf new file mode 100644 index 0000000..cf2ae71 --- /dev/null +++ b/test/annots.vcf @@ -0,0 +1,37 @@ +##fileformat=VCFv4.1 +##INFO= +##FORMAT= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FILTER= +##FILTER= +##contig= +##contig= +##contig= +##contig= +##test= +##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta +##readme=AAAAAA +##readme=BBBBBB +##INFO= +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B +1 3000150 id1 C T 99 PASS STR=id1;AN=4;AC=0 GT:GQ 0|0:999 0|0:999 +1 3000151 id2 C T 99 PASS STR=id2;AN=4;AC=0 GT:DP:GQ 0|0:99:999 0|0:99:999 +1 3062915 idIndel GTTT G 99 PASS DP4=1,2,3,4;AN=4;AC=0;INDEL;STR=testIndel GT:GQ:DP:GL 0|0:999:99:-99,-9,-99 0|0:999:99:-99,-9,-99 +1 3062915 idSNP G T,C 99 PASS STR=testSNP;TEST=5;DP4=1,2,3,4;AN=3;AC=0,0 GT:TT:GQ:DP:GL 0|0:9,9:999:99:-99,-9,-99,-99,-9,-99 0:9,9:999:99:-99,-9,-99 +1 3106154 id4 CAAA C 99 PASS STR=id4;AN=4;AC=0 GT:GQ:DP 0|0:999:99 0|0:999:99 +1 3106154 id5 C CT 99 PASS STR=id5;AN=4;AC=0 GT:GQ:DP 0|0:999:99 0|0:999:99 +1 3157410 id6 GA GC,G 99 PASS STR=id6;AN=4;AC=0 GT:GQ:DP 0|0:99:99 0|0:99:99 +1 3162006 id7 GAA GG 99 PASS STR=id7;AN=4;AC=0 GT:GQ:DP 0|0:999:99 0|0:999:99 +1 3177144 id8 G T 99 PASS STR=id8;AN=4;AC=0 GT:GQ:DP 0|0:999:99 0|0:999:99 +1 3177144 id9 G . 99 PASS STR=id9;AN=4;AC=0 GT:GQ:DP 0|0:999:99 0|0:999:99 +1 3184885 id10 TAAAA TA,T 99 PASS STR=id10;AN=4;AC=0,0 GT:GQ:DP 0|0:99:99 0|0:99:99 +2 3199812 id11 G GTT,GT 99 PASS STR=id11;AN=4;AC=0,0 GT:GQ:DP 0|0:999:99 0|0:999:99 +3 3212016 id12 CTT C,CT 99 PASS STR=id12;AN=4;AC=0,0 GT:GQ:DP 0|0:99:99 0|0:99:99 +4 3258448 id13 TACACACAC T 99 PASS STR=id13;AN=4;AC=0 GT:GQ:DP 0|0:999:99 0|0:999:99 diff --git a/test/annots10.tab b/test/annots10.tab new file mode 100644 index 0000000..5128f3c --- /dev/null +++ b/test/annots10.tab @@ -0,0 +1,4 @@ +1 3000001 . . . . . . +1 3000002 88,99 77 8.8,9.9 7.7 888,999 77 +1 3000003 88,99 77 8.8,9.9 7.7 888,999 77 +1 3000004 88,99 77 8.8,9.9 7.7 888,999 77 diff --git a/test/annots11.tab b/test/annots11.tab new file mode 100644 index 0000000..c291827 --- /dev/null +++ b/test/annots11.tab @@ -0,0 +1,4 @@ +1 3000001 . . . +1 3000002 77 7.7 77 +1 3000003 77 7.7 77 +1 3000004 77 7.7 77 diff --git a/test/annots2.vcf b/test/annots2.vcf new file mode 100644 index 0000000..d54a8f6 --- /dev/null +++ b/test/annots2.vcf @@ -0,0 +1,17 @@ +##fileformat=VCFv4.1 +##FILTER= +##contig= +##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta +##INFO= +##INFO= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT B A +1 3000001 . C T . . . GT . . +1 3000002 id C T 99 q99 FLAG;IINT=88,99;IFLT=8.8,9.9;ISTR=888,999 GT:FINT:FFLT:FSTR 1|1:88,99:8.8,9.9:888,999 0|1:77:7.7:77 +1 3000003 id C T 99 q99 FLAG;IINT=88,99;IFLT=8.8,9.9;ISTR=888,999 GT:FINT:FFLT:FSTR 1|1:88,99:8.8,9.9:888,999 0|1:77:7.7:77 +1 3000004 id C T 99 q99 FLAG;IINT=88,99;IFLT=8.8,9.9;ISTR=888,999 GT:FINT:FFLT:FSTR 1|1:88,99:8.8,9.9:888,999 0|1:77:7.7:77 diff --git a/test/annots4.tab b/test/annots4.tab new file mode 100644 index 0000000..1674a40 --- /dev/null +++ b/test/annots4.tab @@ -0,0 +1,3 @@ +1 1 C A,T,G 0,1.1,0 1.1,0,2.2,0 0,1,0 1,0,2,0 X,11,XXX 1,XX,222,XXX +1 2 C T,G 1.1,2.2 1.1,2.2,3.3 1,2 1,2,3 11,2 111,22,3 +1 3 C T 1.1 1.1,2.2 1 1,2 11 11,2 diff --git a/test/annots4.vcf b/test/annots4.vcf new file mode 100644 index 0000000..4f584d0 --- /dev/null +++ b/test/annots4.vcf @@ -0,0 +1,13 @@ +##fileformat=VCFv4.2 +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##contig= +##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta +#CHROM POS ID REF ALT QUAL FILTER INFO +1 1 . C A,T,G . . FA=0,1.1,0;FR=1.1,0,2.2,0;IA=0,1,0;IR=1,0,2,0;SA=X,11,XXX;SR=1,XX,222,XXX +1 2 . C T,G . . FA=1.1,2.2;FR=1.1,2.2,3.3;IA=1,2;IR=1,2,3;SA=11,2;SR=111,22,3 +1 3 . C T . . FA=1.1;FR=1.1,2.2;IA=1;IR=1,2;SA=11;SR=11,2 diff --git a/test/annots9.tab b/test/annots9.tab new file mode 100644 index 0000000..678e3c4 --- /dev/null +++ b/test/annots9.tab @@ -0,0 +1,5 @@ +1 3000150 C T id3000150 +1 3000151 C T id3000151 +1 3062915 GTTT G id3062915_3D +1 3062915 G T,C id3062915_NP +1 3106154 CAAA C id3106154 diff --git a/test/annots9.vcf b/test/annots9.vcf new file mode 100644 index 0000000..6ff2cce --- /dev/null +++ b/test/annots9.vcf @@ -0,0 +1,28 @@ +##fileformat=VCFv4.1 +##INFO= +##FORMAT= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FILTER= +##FILTER= +##contig= +##contig= +##contig= +##contig= +##test= +##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta +##readme=AAAAAA +##readme=BBBBBB +##INFO= +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B +1 3000150 id3000150 C T 59.2 PASS AN=4;AC=2 GT:GQ 0/1:245 0/1:245 +1 3000151 id3000151 C T 59.2 PASS AN=4;AC=2 GT:DP:GQ 0/1:32:245 0/1:32:245 +1 3062915 id3062915_3D GTTT G 12.9 q10 DP4=1,2,3,4;AN=4;AC=2;INDEL;STR=test GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 0/1:409:35:-20,-5,-20 +1 3062915 id3062915_NP G T,C 12.6 test TEST=5;DP4=1,2,3,4;AN=3;AC=1,1 GT:TT:GQ:DP:GL 0/1:0,1:409:35:-20,-5,-20,-20,-5,-20 2:0,1:409:35:-20,-5,-20 +1 3106154 id3106154 CAAA C 342 PASS AN=4;AC=2 GT:GQ:DP 0/1:245:32 0/1:245:32 diff --git a/test/check.chk b/test/check.chk new file mode 100644 index 0000000..c04a1bf --- /dev/null +++ b/test/check.chk @@ -0,0 +1,87 @@ +# +# Definition of sets: +# ID [2]id [3]tab-separated file names +# SN, Summary numbers: +# SN [2]id [3]key [4]value +SN 0 number of samples: 2 +SN 0 number of records: 18 +SN 0 number of no-ALTs: 1 +SN 0 number of SNPs: 5 +SN 0 number of MNPs: 1 +SN 0 number of indels: 9 +SN 0 number of others: 2 +SN 0 number of multiallelic sites: 6 +SN 0 number of multiallelic SNP sites: 1 +# TSTV, transitions/transversions: +# TSTV [2]id [3]ts [4]tv [5]ts/tv [6]ts (1st ALT) [7]tv (1st ALT) [8]ts/tv (1st ALT) +TSTV 0 3 2 1.50 3 1 3.00 +# SiS, Singleton stats: +# SiS [2]id [3]allele count [4]number of SNPs [5]number of transitions [6]number of transversions [7]number of indels [8]repeat-consistent [9]repeat-inconsistent [10]not applicable +SiS 0 1 3 1 2 0 0 0 0 +# AF, Stats by non-reference allele frequency: +# AF [2]id [3]allele frequency [4]number of SNPs [5]number of transitions [6]number of transversions [7]number of indels [8]repeat-consistent [9]repeat-inconsistent [10]not applicable +AF 0 0.000000 3 1 2 2 0 0 2 +AF 0 0.490000 0 0 0 12 0 0 12 +AF 0 0.740000 1 1 0 0 0 0 0 +AF 0 0.990000 1 1 0 0 0 0 0 +# QUAL, Stats by quality: +# QUAL [2]id [3]Quality [4]number of SNPs [5]number of transitions (1st ALT) [6]number of transversions (1st ALT) [7]number of indels +QUAL 0 12 1 0 1 1 +QUAL 0 45 0 0 0 1 +QUAL 0 59 2 1 0 3 +QUAL 0 60 1 1 0 0 +QUAL 0 61 0 0 0 1 +QUAL 0 79 0 0 0 1 +QUAL 0 82 0 0 0 1 +QUAL 0 90 1 1 0 0 +QUAL 0 342 0 0 0 1 +# IDD, InDel distribution: +# IDD [2]id [3]length (deletions negative) [4]count +IDD 0 -10 1 +IDD 0 -8 1 +IDD 0 -4 3 +IDD 0 -3 4 +IDD 0 -2 1 +IDD 0 -1 2 +IDD 0 1 1 +IDD 0 2 1 +# ST, Substitution types: +# ST [2]id [3]type [4]count +ST 0 A>C 0 +ST 0 A>G 0 +ST 0 A>T 0 +ST 0 C>A 0 +ST 0 C>G 0 +ST 0 C>T 0 +ST 0 G>A 3 +ST 0 G>C 1 +ST 0 G>T 1 +ST 0 T>A 0 +ST 0 T>C 0 +ST 0 T>G 0 +# DP, Depth distribution +# DP [2]id [3]bin [4]number of genotypes [5]fraction of genotypes (%) [6]number of sites [7]fraction of sites (%) +DP 0 10 2 5.555556 0 0.000000 +DP 0 21 2 5.555556 0 0.000000 +DP 0 22 2 5.555556 0 0.000000 +DP 0 26 4 11.111111 0 0.000000 +DP 0 30 2 5.555556 0 0.000000 +DP 0 31 16 44.444444 0 0.000000 +DP 0 32 4 11.111111 0 0.000000 +DP 0 35 4 11.111111 0 0.000000 +DP 0 60 0 0.000000 1 33.333333 +DP 0 62 0 0.000000 2 66.666667 +# PSC, Per-sample counts +# PSC [2]id [3]sample [4]nRefHom [5]nNonRefHom [6]nHets [7]nTransitions [8]nTransversions [9]nIndels [10]average depth [11]nSingletons +PSC 0 A 0 2 4 3 2 9 28.7 1 +PSC 0 B 1 1 4 2 2 9 28.7 0 +# PSI, Per-Sample Indels +# PSI [2]id [3]sample [4]in-frame [5]out-frame [6]not applicable [7]out/(in+out) ratio [8]nHets [9]nAA +PSI 0 A 0 0 0 0.00 9 0 +PSI 0 B 0 0 0 0.00 9 0 +# HWE +# HWE [2]id [3]1st ALT allele frequency [4]Number of observations [5]25th percentile [6]median [7]75th percentile +HWE 0 0.000000 2 0.490000 0.490000 0.990000 +HWE 0 0.490000 14 0.990000 0.990000 0.990000 +HWE 0 0.740000 1 0.490000 0.490000 0.490000 +HWE 0 0.990000 1 0.000000 0.000000 0.000000 diff --git a/test/check.gs.chrom.gen b/test/check.gs.chrom.gen new file mode 100644 index 0000000..7406028 --- /dev/null +++ b/test/check.gs.chrom.gen @@ -0,0 +1,10 @@ +1 1:3062915_GTTT_G 3062915 GTTT G 0 1 0 0 1 0 +1 1:3106154_CAAA_C 3106154 CAAA C 0 1 0 0 1 0 +1 1:3157410_G_A 3157410 G A 0 0 1 0 0 1 +1 1:3162006_G_A 3162006 G A 0 0 1 0 1 0 +1 1:3177144_GT_G 3177144 GT G 0 1 0 0 1 0 +4 4:3258448_TACACACAC_T 3258448 TACACACAC T 0 1 0 0 1 0 +4 4:3258451_AAA_AGT 3258451 AAA AGT 0 1 0 0 1 0 +4 4:3258452_AAA_AGA 3258452 AAA AGA 0 1 0 0 1 0 +4 4:3258453_AACA_AGA 3258453 AACA AGA 0 1 0 0 1 0 +4 4:3258454_AACA_AACA 3258454 AACA AACA 0 1 0 0 1 0 diff --git a/test/check.gs.chrom.samples b/test/check.gs.chrom.samples new file mode 100644 index 0000000..dd870ec --- /dev/null +++ b/test/check.gs.chrom.samples @@ -0,0 +1,4 @@ +ID_1 ID_2 missing +0 0 0 +A A 0 +B B 0 diff --git a/test/check.gs.vcfids.gen b/test/check.gs.vcfids.gen new file mode 100644 index 0000000..1d7387c --- /dev/null +++ b/test/check.gs.vcfids.gen @@ -0,0 +1,10 @@ +1:3062915_GTTT_G id3D 3062915 GTTT G 0 1 0 0 1 0 +1:3106154_CAAA_C . 3106154 CAAA C 0 1 0 0 1 0 +1:3157410_G_A . 3157410 G A 0 0 1 0 0 1 +1:3162006_G_A . 3162006 G A 0 0 1 0 1 0 +1:3177144_GT_G . 3177144 GT G 0 1 0 0 1 0 +4:3258448_TACACACAC_T . 3258448 TACACACAC T 0 1 0 0 1 0 +4:3258451_AAA_AGT . 3258451 AAA AGT 0 1 0 0 1 0 +4:3258452_AAA_AGA . 3258452 AAA AGA 0 1 0 0 1 0 +4:3258453_AACA_AGA . 3258453 AACA AGA 0 1 0 0 1 0 +4:3258454_AACA_AACA . 3258454 AACA AACA 0 1 0 0 1 0 diff --git a/test/check.gs.vcfids.samples b/test/check.gs.vcfids.samples new file mode 100644 index 0000000..dd870ec --- /dev/null +++ b/test/check.gs.vcfids.samples @@ -0,0 +1,4 @@ +ID_1 ID_2 missing +0 0 0 +A A 0 +B B 0 diff --git a/test/check.gs.vcfids_chrom.gen b/test/check.gs.vcfids_chrom.gen new file mode 100644 index 0000000..80c12be --- /dev/null +++ b/test/check.gs.vcfids_chrom.gen @@ -0,0 +1,10 @@ +1 id3D 3062915 GTTT G 0 1 0 0 1 0 +1 . 3106154 CAAA C 0 1 0 0 1 0 +1 . 3157410 G A 0 0 1 0 0 1 +1 . 3162006 G A 0 0 1 0 1 0 +1 . 3177144 GT G 0 1 0 0 1 0 +4 . 3258448 TACACACAC T 0 1 0 0 1 0 +4 . 3258451 AAA AGT 0 1 0 0 1 0 +4 . 3258452 AAA AGA 0 1 0 0 1 0 +4 . 3258453 AACA AGA 0 1 0 0 1 0 +4 . 3258454 AACA AACA 0 1 0 0 1 0 diff --git a/test/check.gs.vcfids_chrom.samples b/test/check.gs.vcfids_chrom.samples new file mode 100644 index 0000000..dd870ec --- /dev/null +++ b/test/check.gs.vcfids_chrom.samples @@ -0,0 +1,4 @@ +ID_1 ID_2 missing +0 0 0 +A A 0 +B B 0 diff --git a/test/check.vcf b/test/check.vcf new file mode 100644 index 0000000..055fd43 --- /dev/null +++ b/test/check.vcf @@ -0,0 +1,38 @@ +##fileformat=VCFv4.1 +##INFO= +##FORMAT= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FILTER= +##FILTER= +##contig= +##contig= +##contig= +##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta +##readme=AAAAAA +##readme=BBBBBB +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B +1 3062915 id3D GTTT G 12.9 q10 DP4=1,2,3,4;AN=4;AC=2 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 0/1:409:35:-20,-5,-20 +1 3062915 idSNP G T,C 12.6 test TEST=5;DP4=1,2,3,4;AN=4;AC=1,1 GT:TT:GQ:DP:GL 0/1:0,1:409:35:-20,-5,-20,-20,-5,-20 0/2:0,1:409:35:-20,-5,-20,-20,-5,-20 +1 3106154 . CAAA C 342 PASS AN=4;AC=2 GT:GQ:DP 0/1:245:32 0/1:245:32 +1 3106154 . G A 59.2 PASS AN=4;AC=1 GT:GQ:DP 0/1:245:32 0/0:245:32 +1 3157410 . G A 90.6 q10 AN=4;AC=4 GT:GQ:DP 1/1:21:21 1/1:21:21 +1 3162006 . G A 60.2 PASS AN=4;AC=3 GT:GQ:DP 1/1:212:22 0/1:212:22 +1 3177144 . GT G 45 PASS AN=4;AC=2 GT:GQ:DP 0/1:150:30 0/1:150:30 +1 3184885 . TAAAA TA,T 61.5 PASS AN=4;AC=2,2 GT:GQ:DP 1/2:12:10 1/2:12:10 +2 3199812 . G GTT,GT 82.7 PASS AN=4;AC=2,2 GT:GQ:DP 1/2:322:26 1/2:322:26 +3 3212016 . CTT C,CT 79 PASS AN=4;AC=2,2 GT:GQ:DP 1/2:91:26 1/2:91:26 +4 3258448 . TACACACAC T 59.9 PASS DP=62;AN=4;AC=2 GT:GQ:DP 0/1:325:31 0/1:325:31 +4 3258449 . GCAAA GA,G 59.9 PASS DP=62;AN=4;AC=2 GT:GQ:DP 0/1:325:31 0/1:325:31 +4 3258450 . AAAAGAAAAAG A,AAAAAAG 59.9 PASS DP=60;AN=4;AC=2 GT:GQ:DP 0/1:325:31 0/1:325:31 +4 3258451 . AAA AGT 59.9 PASS AN=4;AC=2 GT:GQ:DP 0/1:325:31 0/1:325:31 +4 3258452 . AAA AGA 59.9 PASS AN=4;AC=2 GT:GQ:DP 0/1:325:31 0/1:325:31 +4 3258453 . AACA AGA 59.9 PASS AN=4;AC=2 GT:GQ:DP 0/1:325:31 0/1:325:31 +4 3258453 . ACA AAGA 59.9 PASS AN=4;AC=2 GT:GQ:DP 0/1:325:31 0/1:325:31 +4 3258454 . AACA AACA 59.9 PASS AN=4;AC=2 GT:GQ:DP 0/1:325:31 0/1:325:31 diff --git a/test/check_merge.chk b/test/check_merge.chk new file mode 100644 index 0000000..5d56682 --- /dev/null +++ b/test/check_merge.chk @@ -0,0 +1,65 @@ +# +# Definition of sets +# ID [2]id [3]tab-separated file names +# SN, Summary numbers +# SN [2]id [3]key [4]value +SN 0 number of samples: 2 +SN 0 number of records: 18 +SN 0 number of no-ALTs: 1 +SN 0 number of SNPs: 5 +SN 0 number of MNPs: 1 +SN 0 number of indels: 9 +SN 0 number of others: 2 +SN 0 number of multiallelic sites: 6 +SN 0 number of multiallelic SNP sites: 1 +# # TSTV, transition/transversions: +# TSTV [2]id [3]ts [4]tv [5]ts/tv [6]ts (1st ALT) [7]tv (1st ALT) [8]ts/tv (1st ALT) +TSTV 0 3 2 1.50 3 1 3.00 +# Sis, Singleton stats +# SiS [2]id [3]allele count [4]number of SNPs [5]number of transitions [6]number of transversions [7]number of indels [8]repeat-consistent [9]repeat-inconsistent [10]not applicable +SiS 0 1 3 1 2 0 0 0 0 +# AF, Stats by non-reference allele frequency +# AF [2]id [3]allele frequency [4]number of SNPs [5]number of transitions [6]number of transversions [7]number of indels [8]repeat-consistent [9]repeat-inconsistent [10]not applicable +AF 0 0.000000 3 1 2 2 0 0 2 +AF 0 0.490000 0 0 0 12 0 0 12 +AF 0 0.740000 1 1 0 0 0 0 0 +AF 0 0.990000 1 1 0 0 0 0 0 +# IDD, InDel distribution +# IDD [2]id [3]length (deletions negative) [4]count +IDD 0 -10 1 +IDD 0 -8 1 +IDD 0 -4 3 +IDD 0 -3 4 +IDD 0 -2 1 +IDD 0 -1 2 +IDD 0 1 1 +IDD 0 2 1 +# ST, Substitution types +# ST [2]id [3]type [4]count +ST 0 A>C 0 +ST 0 A>G 0 +ST 0 A>T 0 +ST 0 C>A 0 +ST 0 C>G 0 +ST 0 C>T 0 +ST 0 G>A 3 +ST 0 G>C 1 +ST 0 G>T 1 +ST 0 T>A 0 +ST 0 T>C 0 +ST 0 T>G 0 +# DP, Depth distribution +# DP [2]id [3]bin [4]number of genotypes [5]fraction of genotypes (%) [6]number of sites [7]fraction of sites (%) +DP 0 60 0 0.000000 1 33.333333 +DP 0 62 0 0.000000 2 66.666667 +# QUAL, Stats by quality +# QUAL [2]id [3]Quality [4]number of SNPs [5]number of transitions (1st ALT) [6]number of transversions (1st ALT) [7]number of indels +QUAL 0 12 1 0 1 1 +QUAL 0 45 0 0 0 1 +QUAL 0 59 2 1 0 3 +QUAL 0 60 1 1 0 0 +QUAL 0 61 0 0 0 1 +QUAL 0 79 0 0 0 1 +QUAL 0 82 0 0 0 1 +QUAL 0 90 1 1 0 0 +QUAL 0 342 0 0 0 1 diff --git a/test/concat.1.a.vcf b/test/concat.1.a.vcf new file mode 100644 index 0000000..77912a6 --- /dev/null +++ b/test/concat.1.a.vcf @@ -0,0 +1,30 @@ +##fileformat=VCFv4.0 +##FILTER= +##FILTER= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##contig= +##contig= +##samtoolsVersion=0.2.0-rc10+htslib-0.2.0-rc10 +##samtoolsCommand=samtools mpileup -t INFO/DPR -C50 -pm3 -F0.2 -d10000 -ug -r 1:1-1000000 -b mpileup.2014-07-03//lists/chr1-pooled.list -f human_g1k_v37.fasta +##ALT= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A +1 100 . GTTT G 1806 q10 XX=11;DP=35 GT:GQ:DP 0/1:409:35 +1 110 . C T,G 1792 Fail DP=32 GT:GQ:DP 0/1:245:32 +1 110 . CAAA C 1792 Fail DP=32 GT:GQ:DP 0/1:245:32 +1 120 . GA G 628 q10 DP=21 GT:GQ:DP 1/1:21:21 +1 130 . G T 1016 Fail DP=22 GT:GQ:DP 0/1:212:22 +1 130 . GAA GG 1016 Fail DP=22 GT:GQ:DP 0/1:212:22 +1 140 . GT G 727 PASS DP=30 GT:GQ:DP 0/1:150:30 +1 150 . TAAAA TA,T 246 Fail DP=10 GT:GQ:DP 1/2:12:10 +1 160 . TAAAA TA,T 246 Fail DP=10 GT:GQ:DP 1/2:12:10 +2 100 . GTTT G 1806 q10 DP=35 GT:GQ:DP 0/1:409:35 +2 110 . CAAA C 1792 PASS DP=32 GT:GQ:DP 0/1:245:32 +2 120 . GA G 628 q10 DP=21 GT:GQ:DP 1/1:21:21 +2 130 . GAA G 1016 PASS DP=22 GT:GQ:DP 0/1:212:22 +2 140 . GT G 727 PASS DP=30 GT:GQ:DP 0/1:150:30 +2 150 . TAAAA TA,T 246 PASS DP=10 GT:GQ:DP 1/2:12:10 +2 160 . TAAAA TA,TC,T 246 PASS DP=10 GT:GQ:DP 0/2:12:10 diff --git a/test/concat.1.b.vcf b/test/concat.1.b.vcf new file mode 100644 index 0000000..4bb26e4 --- /dev/null +++ b/test/concat.1.b.vcf @@ -0,0 +1,17 @@ +##fileformat=VCFv4.0 +##samtoolsVersion=0.2.0-rc10+htslib-0.2.0-rc10 +##samtoolsCommand=samtools mpileup -t INFO/DPR -C50 -pm3 -F0.2 -d10000 -ug -r 1:1-1000000 -b mpileup.2014-07-03//lists/chr1-pooled.list -f human_g1k_v37.fasta +##ALT= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FILTER= +##contig= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A +3 142 . GTTT G 1806 q10 DP=35 GT:GQ:DP 0/1:409:35 +3 152 . CAAA C 1792 PASS DP=32 GT:GQ:DP 0/1:245:32 +3 162 . GA G 628 q10 DP=21 GT:GQ:DP 1/1:21:21 +3 172 . GAA G 1016 PASS DP=22 GT:GQ:DP 0/1:212:22 +3 182 . GT G 727 PASS DP=30 GT:GQ:DP 0/1:150:30 +3 192 . 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GTTT G 1806 q10 DP=35 GT:GQ:DP:PS 0|1:409:35:202 0|1:.:.:202 +9 212 . C T,G 1792 PASS DP=32 GT:GQ:DP:PS 0|1:245:32:202 0|1:.:.:202 +9 212 . CAAA C 1792 PASS DP=32 GT:GQ:DP:PS 0|1:245:32:202 0|1:.:.:202 +9 222 . GA G 628 q10 DP=21 GT:GQ:DP:PS 0|1:21:21:202 0|1:.:.:202 +9 232 . G T 1016 PASS DP=22 GT:GQ:DP:PS 0|1:212:22:202 0|1:.:.:202 +9 232 . GAA GG 1016 PASS DP=22 GT:GQ:DP:PS 0|1:212:22:202 0|1:.:.:202 +9 242 . GT G 727 PASS DP=30 GT:GQ:DP:PS 0|1:150:30:202 0|1:.:.:202 +9 252 . TAAAA TA,T 246 PASS DP=10 GT:GQ:DP:PS 0|1:12:10:202 0|1:.:.:202 +9 262 . TAAAA TA,T 246 PASS DP=10 GT:GQ:DP:PS 0|1:12:10:202 0|1:.:.:202 +1 100 . GTTT G 1806 q10 DP=35 GT:GQ:DP:PS 0|1:409:35:100 0|1:.:.:100 +1 110 . C T,G 1792 PASS DP=32 GT:GQ:DP:PS 0|1:245:32:100 0|1:.:.:100 +1 110 . CAAA C 1792 PASS DP=32 GT:GQ:DP:PS 0|1:245:32:100 0|1:.:.:100 +1 120 . GA G 628 q10 DP=21 GT:GQ:DP:PS 0|1:21:21:100 0|1:.:.:100 +1 130 . G T 1016 PASS DP=22 GT:GQ:DP:PS 0|1:212:22:100 0|1:.:.:100 +1 130 . GAA GG 1016 PASS DP=22 GT:GQ:DP:PS 0|1:212:22:100 0|1:.:.:100 +1 140 . GT G 727 PASS DP=30 GT:GQ:DP:PS 0|1:150:30:100 0|1:.:.:100 +1 150 . TAAAA TA,T 246 PASS DP=10 GT:GQ:DP:PS 0|1:12:10:100 0|1:.:.:100 +1 160 . TAAAA TA,T 246 PASS DP=10 GT:GQ:DP:PS 0|1:12:10:100 0|1:.:.:100 +2 170 . T A 246 PASS DP=10 GT:PS 1|0:170 0|1:170 +2 180 . T A 246 PASS DP=10 GT:PS 1|0:170 0|1:170 +2 190 . T A 246 PASS DP=10 GT:PS 1|0:170 0|1:170 +2 200 . T A 246 PASS DP=10 GT:PS 1|0:170 0|1:170 +2 210 . T A 246 PASS DP=10 GT:PS 1|0:170 0|1:170 +2 220 . T A 246 PASS DP=10 GT:PS 1|0:170 0|1:170 +2 230 . T A 246 PASS DP=10 GT:PS 1|0:170 0|1:170 +2 240 . T A 246 PASS DP=10 GT:PS 1|0:170 0|1:170 +2 250 . T A 246 PASS DP=10 GT:PS 1|0:170 0|1:170 +2 260 . T A 246 PASS DP=10 GT:PS 1|0:170 0|1:170 +2 270 . T A 246 PASS DP=10 GT:PS 1|0:170 0|1:170 +2 280 . T A 246 PASS DP=10 GT:PS 1|0:170 0|1:170 +2 290 . T A 246 PASS DP=10 GT:PS 1|0:170 0|1:170 +2 300 . T A 246 PASS DP=10 GT:PS 1|0:170 0|1:170 +2 310 . T A 246 PASS DP=10 GT:PQ:PS 1|0:3:310 0|1:28:310 +2 320 . T A 246 PASS DP=10 GT:PS 1|0:310 0|1:310 +2 330 . T A 246 PASS DP=10 GT:PS 1|0:310 0|1:310 +2 340 . T A 246 PASS DP=10 GT:PS 1|0:310 0|1:310 +2 350 . T A 246 PASS DP=10 GT:PS 1|0:310 0|1:310 +2 360 . T A 246 PASS DP=10 GT:PS 1|0:310 0|1:310 +2 370 . T A 246 PASS DP=10 GT:PQ:PS 1|0:99:310 0|1:99:310 +2 380 . T A 246 PASS DP=10 GT:PS 1|0:310 0|1:310 +2 390 . T A 246 PASS DP=10 GT:PS 1|0:310 0|1:310 +2 490 . T A 246 PASS DP=10 GT:PS 1|0:310 0|1:310 +2 500 . T A 246 PASS DP=10 GT:PS 1|0:310 0|1:310 +2 510 . T A 246 PASS DP=10 GT:PQ:PS 1|0:99:310 0|1:99:310 +3 380 . T A 246 PASS DP=10 GT:PS 0|1:380 1|0:380 +3 390 . T A 246 PASS DP=10 GT:PS 0|1:380 1|0:380 +3 400 . T A 246 PASS DP=10 GT:PS 0|1:380 1|0:380 +3 410 . T A 246 PASS DP=10 GT:PS 0|1:380 1|0:380 +3 420 . T A 246 PASS DP=10 GT:PS 0|1:380 1|0:380 +3 430 . T A 246 PASS DP=10 GT:PS 0|1:380 1|0:380 +3 440 . T A 246 PASS DP=10 GT:PS 0|1:380 1|0:380 +3 450 . T A 246 PASS DP=10 GT:PS 0|1:380 1|0:380 +3 460 . T A 246 PASS DP=10 GT:PS 0|1:380 1|0:380 +3 470 . T A 246 PASS DP=10 GT:PS 0|1:380 1|0:380 +3 480 . T A 246 PASS DP=10 GT:PS 0|1:380 1|0:380 +3 490 . T A 246 PASS DP=10 GT:PS 0|1:380 1|0:380 diff --git a/test/concat.3.c.vcf b/test/concat.3.c.vcf new file mode 100644 index 0000000..6b436dd --- /dev/null +++ b/test/concat.3.c.vcf @@ -0,0 +1,22 @@ +##fileformat=VCFv4.0 +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FILTER= +##contig= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B +2 280 . T A 246 PASS DP=10 GT 1|0 0|1 +2 290 . T A 246 PASS DP=10 GT 1|0 1|0 +2 300 . T A 246 PASS DP=10 GT 0|1 1|0 +2 310 . T A 246 PASS DP=10 GT 0|1 1|0 +2 320 . T A 246 PASS DP=10 GT 0|1 1|0 +2 330 . T A 246 PASS DP=10 GT 0|1 1|0 +2 340 . T A 246 PASS DP=10 GT 0|1 1|0 +2 350 . T A 246 PASS DP=10 GT 0|1 1|0 +2 360 . T A 246 PASS DP=10 GT 0|1 1|0 +2 370 . T A 246 PASS DP=10 GT 0|1 1|0 +2 380 . T A 246 PASS DP=10 GT 0|1 1|0 +2 390 . T A 246 PASS DP=10 GT 0|1 1|0 +2 400 . T A 246 PASS DP=10 GT 0|1 1|0 +2 410 . T A 246 PASS DP=10 GT 0|1 1|0 diff --git a/test/concat.3.d.vcf b/test/concat.3.d.vcf new file mode 100644 index 0000000..3e0f9f4 --- /dev/null +++ b/test/concat.3.d.vcf @@ -0,0 +1,20 @@ +##fileformat=VCFv4.0 +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FILTER= +##contig= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B +2 300 . T A 246 PASS DP=10 GT 1|0 1|0 +2 320 . T A 246 PASS DP=10 GT 1|0 1|0 +2 330 . T A 246 PASS DP=10 GT 1|0 1|0 +2 340 . T A 246 PASS DP=10 GT 1|0 1|0 +2 350 . T A 246 PASS DP=10 GT 1|0 1|0 +2 360 . T A 246 PASS DP=10 GT 1|0 1|0 +2 370 . T A 246 PASS DP=10 GT 1|0 1|0 +2 380 . T A 246 PASS DP=10 GT 1|0 1|0 +2 390 . T A 246 PASS DP=10 GT 1|0 1|0 +2 490 . T A 246 PASS DP=10 GT 1|0 1|0 +2 500 . T A 246 PASS DP=10 GT 1|0 1|0 +2 510 . T A 246 PASS DP=10 GT 1|0 1|0 diff --git a/test/concat.3.e.vcf b/test/concat.3.e.vcf new file mode 100644 index 0000000..380cb99 --- /dev/null +++ b/test/concat.3.e.vcf @@ -0,0 +1,20 @@ +##fileformat=VCFv4.0 +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FILTER= +##contig= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B +2 310 . T A 246 PASS DP=10 GT 0|1 0|1 +2 320 . T A 246 PASS DP=10 GT 0|1 0|1 +2 330 . T A 246 PASS DP=10 GT 0|1 0|1 +2 340 . T A 246 PASS DP=10 GT 0|1 0|1 +2 350 . T A 246 PASS DP=10 GT 0|1 0|1 +2 360 . T A 246 PASS DP=10 GT 0|1 0|1 +2 370 . T A 246 PASS DP=10 GT 0|1 0|1 +2 380 . T A 246 PASS DP=10 GT 0|1 0|1 +2 390 . T A 246 PASS DP=10 GT 0|1 0|1 +2 490 . T A 246 PASS DP=10 GT 0|1 0|1 +2 500 . T A 246 PASS DP=10 GT 0|1 0|1 +2 510 . T A 246 PASS DP=10 GT 0|1 0|1 diff --git a/test/concat.3.f.vcf b/test/concat.3.f.vcf new file mode 100644 index 0000000..0e44436 --- /dev/null +++ b/test/concat.3.f.vcf @@ -0,0 +1,20 @@ +##fileformat=VCFv4.0 +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FILTER= +##contig= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B +3 380 . T A 246 PASS DP=10 GT 1|0 1|0 +3 390 . T A 246 PASS DP=10 GT 1|0 1|0 +3 400 . T A 246 PASS DP=10 GT 1|0 1|0 +3 410 . T A 246 PASS DP=10 GT 1|0 1|0 +3 420 . T A 246 PASS DP=10 GT 1|0 1|0 +3 430 . T A 246 PASS DP=10 GT 1|0 1|0 +3 440 . T A 246 PASS DP=10 GT 1|0 1|0 +3 450 . T A 246 PASS DP=10 GT 1|0 1|0 +3 460 . T A 246 PASS DP=10 GT 1|0 1|0 +3 470 . T A 246 PASS DP=10 GT 1|0 1|0 +3 480 . T A 246 PASS DP=10 GT 1|0 1|0 +3 490 . T A 246 PASS DP=10 GT 1|0 1|0 diff --git a/test/concat.3.vcf.out b/test/concat.3.vcf.out new file mode 100644 index 0000000..ff1dfd3 --- /dev/null +++ b/test/concat.3.vcf.out @@ -0,0 +1,269 @@ +##fileformat=VCFv4.0 +##FILTER= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FILTER= +##contig= +##contig= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##contig= +##contig= +##FORMAT= +##FORMAT= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B +9 202 . GTTT G 1806 q10 DP=35 GT:GQ:DP:PS 0|1:409:35:202 0|1:.:.:202 +9 212 . C T,G 1792 PASS DP=32 GT:GQ:DP:PS 0|1:245:32:202 0|1:.:.:202 +9 212 . CAAA C 1792 PASS DP=32 GT:GQ:DP:PS 0|1:245:32:202 0|1:.:.:202 +9 222 . GA G 628 q10 DP=21 GT:GQ:DP:PS 0|1:21:21:202 0|1:.:.:202 +9 232 . G T 1016 PASS DP=22 GT:GQ:DP:PS 0|1:212:22:202 0|1:.:.:202 +9 232 . GAA GG 1016 PASS DP=22 GT:GQ:DP:PS 0|1:212:22:202 0|1:.:.:202 +9 242 . GT G 727 PASS DP=30 GT:GQ:DP:PS 0|1:150:30:202 0|1:.:.:202 +9 252 . TAAAA TA,T 246 PASS DP=10 GT:GQ:DP:PS 0|1:12:10:202 0|1:.:.:202 +9 262 . TAAAA TA,T 246 PASS DP=10 GT:GQ:DP:PS 0|1:12:10:202 0|1:.:.:202 +1 100 . GTTT G 1806 q10 DP=35 GT:GQ:DP:PS 0|1:409:35:100 0|1:.:.:100 +1 110 . C T,G 1792 PASS DP=32 GT:GQ:DP:PS 0|1:245:32:100 0|1:.:.:100 +1 110 . CAAA C 1792 PASS DP=32 GT:GQ:DP:PS 0|1:245:32:100 0|1:.:.:100 +1 120 . GA G 628 q10 DP=21 GT:GQ:DP:PS 0|1:21:21:100 0|1:.:.:100 +1 130 . G T 1016 PASS DP=22 GT:GQ:DP:PS 0|1:212:22:100 0|1:.:.:100 +1 130 . GAA GG 1016 PASS DP=22 GT:GQ:DP:PS 0|1:212:22:100 0|1:.:.:100 +1 140 . GT G 727 PASS DP=30 GT:GQ:DP:PS 0|1:150:30:100 0|1:.:.:100 +1 150 . TAAAA TA,T 246 PASS DP=10 GT:GQ:DP:PS 0|1:12:10:100 0|1:.:.:100 +1 160 . TAAAA TA,T 246 PASS DP=10 GT:GQ:DP:PS 0|1:12:10:100 0|1:.:.:100 +2 170 . T A 246 PASS DP=10 GT:PS 1|0:170 0|1:170 +2 180 . T A 246 PASS DP=10 GT:PS 1|0:170 0|1:170 +2 190 . T A 246 PASS DP=10 GT:PS 1|0:170 0|1:170 +2 200 . T A 246 PASS DP=10 GT:PS 1|0:170 0|1:170 +2 210 . T A 246 PASS DP=10 GT:PS 1|0:170 0|1:170 +2 220 . T A 246 PASS DP=10 GT:PS 1|0:170 0|1:170 +2 230 . T A 246 PASS DP=10 GT:PS 1|0:170 0|1:170 +2 240 . T A 246 PASS DP=10 GT:PS 1|0:170 0|1:170 +2 250 . T A 246 PASS DP=10 GT:PS 1|0:170 0|1:170 +2 260 . T A 246 PASS DP=10 GT:PS 1|0:170 0|1:170 +2 270 . T A 246 PASS DP=10 GT:PS 1|0:170 0|1:170 +2 280 . T A 246 PASS DP=10 GT:PS 1|0:170 0|1:170 +2 290 . T A 246 PASS DP=10 GT:PS 1|0:170 0|1:170 +2 300 . T A 246 PASS DP=10 GT:PS 1|0:170 0|1:170 +2 310 . T A 246 PASS DP=10 GT:PQ:PS 1|0:3:310 0|1:28:310 +2 320 . T A 246 PASS DP=10 GT:PS 1|0:310 0|1:310 +2 330 . T A 246 PASS DP=10 GT:PS 1|0:310 0|1:310 +2 340 . T A 246 PASS DP=10 GT:PS 1|0:310 0|1:310 +2 350 . T A 246 PASS DP=10 GT:PS 1|0:310 0|1:310 +2 360 . T A 246 PASS DP=10 GT:PS 1|0:310 0|1:310 +2 370 . T A 246 PASS DP=10 GT:PQ:PS 1|0:99:310 0|1:99:310 +2 380 . T A 246 PASS DP=10 GT:PS 1|0:310 0|1:310 +2 390 . T A 246 PASS DP=10 GT:PS 1|0:310 0|1:310 +2 490 . T A 246 PASS DP=10 GT:PS 1|0:310 0|1:310 +2 500 . T A 246 PASS DP=10 GT:PS 1|0:310 0|1:310 +2 510 . T A 246 PASS DP=10 GT:PQ:PS 1|0:99:310 0|1:99:310 +3 380 . T A 246 PASS DP=10 GT:PS 0|1:380 1|0:380 +3 390 . T A 246 PASS DP=10 GT:PS 0|1:380 1|0:380 +3 400 . T A 246 PASS DP=10 GT:PS 0|1:380 1|0:380 +3 410 . T A 246 PASS DP=10 GT:PS 0|1:380 1|0:380 +3 420 . T A 246 PASS DP=10 GT:PS 0|1:380 1|0:380 +3 430 . T A 246 PASS DP=10 GT:PS 0|1:380 1|0:380 +3 440 . T A 246 PASS DP=10 GT:PS 0|1:380 1|0:380 +3 450 . T A 246 PASS DP=10 GT:PS 0|1:380 1|0:380 +3 460 . T A 246 PASS DP=10 GT:PS 0|1:380 1|0:380 +3 470 . T A 246 PASS DP=10 GT:PS 0|1:380 1|0:380 +3 480 . T A 246 PASS DP=10 GT:PS 0|1:380 1|0:380 +3 490 . T A 246 PASS DP=10 GT:PS 0|1:380 1|0:380 diff --git a/test/concat.4.bcf.out b/test/concat.4.bcf.out new file mode 100644 index 0000000..48166fc --- /dev/null +++ b/test/concat.4.bcf.out @@ -0,0 +1,29 @@ +##fileformat=VCFv4.0 +##FILTER= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FILTER= +##contig= +##contig= +##FILTER= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A +1 100 . GTTT G 1806 q10 DP=35 GT:GQ:DP 0/1:409:35 +1 110 . C T,G 1792 Fail XX=11;DP=32 GT:GQ:DP 0/1:245:32 +1 110 . CAAA C 1792 PASS DP=32 GT:GQ:DP 0/1:245:32 +1 120 . GA G 628 q10 DP=21 GT:GQ:DP 1/1:21:21 +1 130 . GAA GG 1016 PASS DP=22 GT:GQ:DP 0/1:212:22 +1 130 . G T 1016 PASS DP=22 GT:GQ:DP 0/1:212:22 +1 140 . GT G 727 PASS DP=30 GT:GQ:DP 0/1:150:30 +1 150 . TAAAA TA,T 246 PASS DP=10 GT:GQ:DP 1/2:12:10 +1 160 . TAAAA TA,T 246 PASS DP=10 GT:GQ:DP 1/2:12:10 +2 100 . GTTT G 1806 q10 DP=35 GT:GQ:DP 0/1:409:35 +2 110 . CAAA C 1792 PASS DP=32 GT:GQ:DP 0/1:245:32 +2 120 . GA G 628 q10 DP=21 GT:GQ:DP 1/1:21:21 +2 130 . GAA G 1016 PASS DP=22 GT:GQ:DP 0/1:212:22 +2 140 . A G 727 PASS DP=30 GT:GQ:DP 0/1:150:30 +2 140 . GT G 727 PASS DP=30 GT:GQ:DP 0/1:150:30 +2 150 . TAAAA TA,T 246 PASS DP=10 GT:GQ:DP 1/2:12:10 +2 160 . TAAAA TA,TC,T 246 PASS DP=10 GT:GQ:DP 0/2:12:10 diff --git a/test/concat.4.vcf.out b/test/concat.4.vcf.out new file mode 100644 index 0000000..a1553bc --- /dev/null +++ b/test/concat.4.vcf.out @@ -0,0 +1,29 @@ +##fileformat=VCFv4.0 +##FILTER= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FILTER= +##contig= +##contig= +##FILTER= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A +2 100 . GTTT G 1806 q10 DP=35 GT:GQ:DP 0/1:409:35 +2 110 . CAAA C 1792 PASS DP=32 GT:GQ:DP 0/1:245:32 +2 120 . GA G 628 q10 DP=21 GT:GQ:DP 1/1:21:21 +2 130 . GAA G 1016 PASS DP=22 GT:GQ:DP 0/1:212:22 +2 140 . A G 727 PASS DP=30 GT:GQ:DP 0/1:150:30 +2 140 . GT G 727 PASS DP=30 GT:GQ:DP 0/1:150:30 +2 150 . TAAAA TA,T 246 PASS DP=10 GT:GQ:DP 1/2:12:10 +2 160 . TAAAA TA,TC,T 246 PASS DP=10 GT:GQ:DP 0/2:12:10 +1 100 . GTTT G 1806 q10 DP=35 GT:GQ:DP 0/1:409:35 +1 110 . C T,G 1792 Fail XX=11;DP=32 GT:GQ:DP 0/1:245:32 +1 110 . CAAA C 1792 PASS DP=32 GT:GQ:DP 0/1:245:32 +1 120 . GA G 628 q10 DP=21 GT:GQ:DP 1/1:21:21 +1 130 . GAA GG 1016 PASS DP=22 GT:GQ:DP 0/1:212:22 +1 130 . G T 1016 PASS DP=22 GT:GQ:DP 0/1:212:22 +1 140 . GT G 727 PASS DP=30 GT:GQ:DP 0/1:150:30 +1 150 . TAAAA TA,T 246 PASS DP=10 GT:GQ:DP 1/2:12:10 +1 160 . TAAAA TA,T 246 PASS DP=10 GT:GQ:DP 1/2:12:10 diff --git a/test/consensus.1.chain b/test/consensus.1.chain new file mode 100644 index 0000000..2aef343 --- /dev/null +++ b/test/consensus.1.chain @@ -0,0 +1,12 @@ +chain 497 1 501 + 1 501 1 502 + 1 502 1 +11 3 1 +1 0 3 +485 + +chain 485 2 501 + 0 501 2 495 + 0 495 2 +61 3 1 +54 3 1 +58 0 8 +21 10 0 +291 + diff --git a/test/consensus.1.out b/test/consensus.1.out new file mode 100644 index 0000000..df1a7c4 --- /dev/null +++ b/test/consensus.1.out @@ -0,0 +1,20 @@ +>1:2-501 +TACAAAATATGATAAAATCAAAAAGAACATAACCTACGTATCAACTAAAGTGGTTGTTTG +AAGAAAAGGAAGACTTAAAAAGAGTCAGTACTAACCTACATAATATATACAATGTTCATT +AAATAATAAAATGAGCTCATCATACTTAGGTCATCATAAATATATCTGAAATTCACAAAT +ATTGATCAAATGGTAAAATAGACAAGTAGATTTTAATAGGTTAAACAATTACTGATTCTC +TTGAAAGAATAAATTTAATATGAGACCTATTTCATTATAATGAACTCACAAATTAGAAAC +TTCACACTGGGGGCTGGAGAGATGGCTCAGTAGTTAAGAACACTGACTGCTCTTCTGAAG +GTCCTGAGTTCAAATCCCAGCAACCACATGGTGACTTACAACCATCTGTAATGACATCTG +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +TTTAAAAACAAAAAAAAAGAA +>2 +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +AAATTAGTGATTTTCCATATTCTTTAAGTCATTTTAGAGTAATGTGTTCTTAAGATTTCA +GAAAAACAAAAACTTGTGCTTTCCTGTTTGAAAAACAAACAGCTGTGGGGAATGGACGTA +CGTTGTCGGGACAGCCTTTTTATAAAATAATGTTGAGGCTTTGATACGTCAAAGNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTTTGCT +GCTGCCAATGACAGCACACCCTGGGAATGCCCCAACTACTTACTACAAAGCAGTGTTACA +TGGAGAAGATCTTCAAGAGTCTTTTTGCTAGATCTTTCCTTGGCTTTTGATGTGACTCCT +CTCAATAAAATCCACAGTAATATAGTGAGTGGTCTCCTGCTCCAAACCAGTATTCCAGAC +ACAGTTAATCCAGAC diff --git a/test/consensus.2.chain b/test/consensus.2.chain new file mode 100644 index 0000000..b98f99b --- /dev/null +++ b/test/consensus.2.chain @@ -0,0 +1,8 @@ +chain 500 1 501 + 1 501 1 504 + 1 504 1 +15 0 3 +485 + +chain 491 2 501 + 0 501 2 491 + 0 491 2 +200 10 0 +291 + diff --git a/test/consensus.2.out b/test/consensus.2.out new file mode 100644 index 0000000..392ff77 --- /dev/null +++ b/test/consensus.2.out @@ -0,0 +1,20 @@ +>1:2-501 +TACCATATGTGACATAAAATAAAAAAGAACATAACCTACGTATCAACTAAAGTGGTTGTT +TGCAGAAAAGGAAGACTTAAAAAGAGTCAGTACTAACCTACATAATATATACAATGTTCA +TTAAATAATAAAATGAGCTCATCATACTTAGGTCATCATAAATATATCTGAAATTCACAA +ATATTGATCAAATGGTAAAATAGACAAGTAGATTTTAATAGGTTAAACAATTACTGATTC +TCTTGAAAGAATAAATTTAATATGAGACCTATTTCATTATAATGAACTCACAAATTAGAA +ACTTCACACTGGGGGCTGGAGAGATGGCTCAGTAGTTAAGAACACTGACTGCTCTTCTGA +AGGTCCTGAGTTCAAATCCCAGCAACCACATGGTGACTTACAACCATCTGTAATGACATC +TGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +NNTTTAAAAACAAAAAAAAAGAA +>2 +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +AGAGATTAGTGATTTTCCATATTCTTTAAGTCATTTTAGAGTAATGTGTTCTTAAGATAA +ATCAGAAAAACAAAAACTTGTGCTTTCCTGTTTGAAAAACAAACAGCTGTGGGGAATGGT +GTCGGGACAGCCTTTTTATAAAATAATGTTGAGGCTTTGATACGTCAAAGNNNNNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTTTGCTGCTG +CCAATGACAGCACACCCTGGGAATGCCCCAACTACTTACTACAAAGCAGTGTTACATGGA +GAAGATCTTCAAGAGTCTTTTTGCTAGATCTTTCCTTGGCTTTTGATGTGACTCCTCTCA +ATAAAATCCACAGTAATATAGTGAGTGGTCTCCTGCTCCAAACCAGTATTTCAGACACAG +TTAATCCAGAC diff --git a/test/consensus.3.chain b/test/consensus.3.chain new file mode 100644 index 0000000..2aef343 --- /dev/null +++ b/test/consensus.3.chain @@ -0,0 +1,12 @@ +chain 497 1 501 + 1 501 1 502 + 1 502 1 +11 3 1 +1 0 3 +485 + +chain 485 2 501 + 0 501 2 495 + 0 495 2 +61 3 1 +54 3 1 +58 0 8 +21 10 0 +291 + diff --git a/test/consensus.3.out b/test/consensus.3.out new file mode 100644 index 0000000..b3bfc3f --- /dev/null +++ b/test/consensus.3.out @@ -0,0 +1,20 @@ +>1:2-501 +TACMAWATRTGATAAAATMAAAAAGAACATAACCTACGTATCAACTAAAGTGGTTGTTTG +MAGAAAAGGAAGACTTAAAAAGAGTCAGTACTAACCTACATAATATATACAATGTTCATT +AAATAATAAAATGAGCTCATCATACTTAGGTCATCATAAATATATCTGAAATTCACAAAT +ATTGATCAAATGGTAAAATAGACAAGTAGATTTTAATAGGTTAAACAATTACTGATTCTC +TTGAAAGAATAAATTTAATATGAGACCTATTTCATTATAATGAACTCACAAATTAGAAAC +TTCACACTGGGGGCTGGAGAGATGGCTCAGTAGTTAAGAACACTGACTGCTCTTCTGAAG +GTCCTGAGTTCAAATCCCAGCAACCACATGGTGACTTACAACCATCTGTAATGACATCTG +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +TTTAAAAACAAAAAAAAAGAA +>2 +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +AAATTAGTGATTTTCCATATTCTTTAAGTCATTTTAGAGTAATGTGTTCTTAAGATTTCA +GAAAAACAAAAACTTGTGCTTTCCTGTTTGAAAAACAAACAGCTGTGGGGAATGGACGTA +CGTTGTCGGGACAGCCTTTTTATAAAATAATGTTGAGGCTTTGATACGTCAAAGNNNNNN +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTTTGCT +GCTGCCAATGACAGCACACCCTGGGAATGCCCCAACTACTTACTACAAAGCAGTGTTACA +TGGAGAAGATCTTCAAGAGTCTTTTTGCTAGATCTTTCCTTGGCTTTTGATGTGACTCCT +CTCAATAAAATCCACAGTAATATAGTGAGTGGTCTCCTGCTCCAAACCAGTATTYCAGAC +ACAGTTAATCCAGAC diff --git a/test/consensus.4.chain b/test/consensus.4.chain new file mode 100644 index 0000000..b98f99b --- /dev/null +++ b/test/consensus.4.chain @@ -0,0 +1,8 @@ +chain 500 1 501 + 1 501 1 504 + 1 504 1 +15 0 3 +485 + +chain 491 2 501 + 0 501 2 491 + 0 491 2 +200 10 0 +291 + diff --git a/test/consensus.4.out b/test/consensus.4.out new file mode 100644 index 0000000..c3983f8 --- /dev/null +++ b/test/consensus.4.out @@ -0,0 +1,20 @@ +>1:2-501 +TACCATATGTGACATAAAATAAAAAAGAACATAACCTACGTATCAACTAAAGTGGTTGTT +TGCAGAAAAGGAAGACTTAAAAAGAGTCAGTACTAACCTACATAATATATACAATGTTCA +TTAAATAATAAAATGAGCTCATCATACTTAGGTCATCATAAATATATCTGAAATTCACAA +ATATTGATCAAATGGTAAAATAGACAAGTAGATTTTAATAGGTTAAACAATTACTGATTC +TCTTGAAAGAATAAATTTAATATGAGACCTATTTCATTATAATGAACTCACAAATTAGAA +ACTTCACACTGGGGGCTGGAGAGATGGCTCAGTAGTTAAGAACACTGACTGCTCTTCTGA +AGGTCCTGAGTTCAAATCCCAGCAACCACATGGTGACTTACAACCATCTGTAATGACATC +TGATGCCCTCTGGTGTGTCTGAAGACAGCTACAGTGTACTTACATAAAATAATAAATAAA +TCTTTAAAAACAAAAAAAAAGAA +>2 +GAAGATCTTTTCCTTATTAAGGATCTGAAGCTCTGTAGATTTGTATTCTATTAAACATGG +AGAGATTAGTGATTTTCCATATTCTTTAAGTCATTTTAGAGTAATGTGTTCTTAAGATAA +ATCAGAAAAACAAAAACTTGTGCTTTCCTGTTTGAAAAACAAACAGCTGTGGGGAATGGT +GTCGGGACAGCCTTTTTATAAAATAATGTTGAGGCTTTGATACGTCAAAGTTATATTTCA +AATGGAATCACTTAGACCTCGTTTCTGAGTGTCAATGGCCATATTGGGGATTTGCTGCTG +CCAATGACAGCACACCCTGGGAATGCCCCAACTACTTACTACAAAGCAGTGTTACATGGA +GAAGATCTTCAAGAGTCTTTTTGCTAGATCTTTCCTTGGCTTTTGATGTGACTCCTCTCA +ATAAAATCCACAGTAATATAGTGAGTGGTCTCCTGCTCCAAACCAGTATTTCAGACACAG +TTAATCCAGAC diff --git a/test/consensus.5.out b/test/consensus.5.out new file mode 100644 index 0000000..4631ebe --- /dev/null +++ b/test/consensus.5.out @@ -0,0 +1,20 @@ +>1:2-501 +TACCATATGTGACATATAAAAAAGAACATAACCTACGTATCAACTAAAGTGGTTGTTTGC +AGAAAAGGAAGACTTAAAAAGAGTCAGTACTAACCTACATAATATATACAATGTTCATTA +AATAATAAAATGAGCTCATCATACTTAGGTCATCATAAATATATCTGAAATTCACAAATA +TTGATCAAATGGTAAAATAGACAAGTAGATTTTAATAGGTTAAACAATTACTGATTCTCT +TGAAAGAATAAATTTAATATGAGACCTATTTCATTATAATGAACTCACAAATTAGAAACT +TCACACTGGGGGCTGGAGAGATGGCTCAGTAGTTAAGAACACTGACTGCTCTTCTGAAGG +TCCTGAGTTCAAATCCCAGCAACCACATGGTGACTTACAACCATCTGTAATGACATCTGA +TGCCCTCTGGTGTGTCTGAAGACAGCTACAGTGTACTTACATAAAATAATAAATAAATCT +TTAAAAACAAAAAAAAAGAA +>2 +GAAGATCTTTTCCTTATTAAGGATCTGAAGCTCTGTAGATTTGTATTCTATTAAACATGG +AGAGATTAGTGATTTTCCATATTCTTTAAGTCATTTTAGAGTAATGTGTTCTTAAGATAA +ATCAGAAAAACAAAAACTTGTGCTTTCCTGTTTGAAAAACAAACAGCTGTGGGGAATGGT +GTCGGGACAGCCTTTTTATAAAATTTTTCTAAATAATGTTGAGGCTTTGATACGTCAAAG +TTATATTTCAAATGGAATCACTTAGACCTCGTTTCTGAGTGTCAATGGCCATATTGGGGA +TTTGCTGCTGCCAATGACAGCACACCCTGGGAATGCCCCAACTACTTACTACAAAGCAGT +GTTACATGGAGAAGATCTTCAAGAGTCTTTTTGCTAGATCTTTCCTTGGCTTTTGATGTG +ACTCCTCTCAATAAAATCCACAGTAATATAGTGAGTGGTCTCCTGCTCCAAACCAGTATT +TCAGACACAGTTAATCCAGAC diff --git a/test/consensus.fa b/test/consensus.fa new file mode 100644 index 0000000..5522e02 --- /dev/null +++ b/test/consensus.fa @@ -0,0 +1,20 @@ +>1:2-501 +TACCATATGTGACATATAAAAAAGAACATAACCTACGTATCAACTAAAGTGGTTGTTTG +CAGAAAAGGAAGACTTAAAAAGAGTCAGTACTAACCTACATAATATATACAATGTTCATT +AAATAATAAAATGAGCTCATCATACTTAGGTCATCATAAATATATCTGAAATTCACAAAT +ATTGATCAAATGGTAAAATAGACAAGTAGATTTTAATAGGTTAAACAATTACTGATTCTC +TTGAAAGAATAAATTTAATATGAGACCTATTTCATTATAATGAACTCACAAATTAGAAAC +TTCACACTGGGGGCTGGAGAGATGGCTCAGTAGTTAAGAACACTGACTGCTCTTCTGAAG +GTCCTGAGTTCAAATCCCAGCAACCACATGGTGACTTACAACCATCTGTAATGACATCTG +ATGCCCTCTGGTGTGTCTGAAGACAGCTACAGTGTACTTACATAAAATAATAAATAAATC +TTTAAAAACAAAAAAAAAGAA +>2 +GAAGATCTTTTCCTTATTAAGGATCTGAAGCTCTGTAGATTTGTATTCTATTAAACATGG +AGAGATTAGTGATTTTCCATATTCTTTAAGTCATTTTAGAGTAATGTGTTCTTAAGATAA +ATCAGAAAAACAAAAACTTGTGCTTTCCTGTTTGAAAAACAAACAGCTGTGGGGAATGGT +GTCGGGACAGCCTTTTTATAAAATTTTTCTAAATAATGTTGAGGCTTTGATACGTCAAAG +TTATATTTCAAATGGAATCACTTAGACCTCGTTTCTGAGTGTCAATGGCCATATTGGGGA +TTTGCTGCTGCCAATGACAGCACACCCTGGGAATGCCCCAACTACTTACTACAAAGCAGT +GTTACATGGAGAAGATCTTCAAGAGTCTTTTTGCTAGATCTTTCCTTGGCTTTTGATGTG +ACTCCTCTCAATAAAATCCACAGTAATATAGTGAGTGGTCTCCTGCTCCAAACCAGTATT +TCAGACACAGTTAATCCAGAC diff --git a/test/consensus.tab b/test/consensus.tab new file mode 100644 index 0000000..a913c02 --- /dev/null +++ b/test/consensus.tab @@ -0,0 +1,3 @@ +1 421 480 +2 1 60 +2 241 300 diff --git a/test/consensus.vcf b/test/consensus.vcf new file mode 100644 index 0000000..007aabf --- /dev/null +++ b/test/consensus.vcf @@ -0,0 +1,18 @@ +##fileformat=VCFv4.2 +##FORMAT= +##INFO= +##ALT= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA001 +1 5 . C a . PASS . GT 0/1 +1 5 . C t . PASS . GT 0/1 +1 7 . T a . PASS . GT . +1 10 . G a . PASS . GT 0/1 +1 12 . GACA ga . PASS . GT 0/1 +1 16 . T taaa . PASS . GT 1/1 +1 19 . A c . PASS . GT 0/1 +1 61 . C a . PASS . GT 0/1 +2 61 . AGAG aa . PASS . GT 0/1 +2 119 . AAA t . PASS . GT 0/1 +2 179 . G gacgtacgt . PASS . GT 0/1 +2 200 . A . PASS END=210 GT 1/0 +2 481 . T c,a . PASS . GT 0/2 diff --git a/test/consensus2.1.out b/test/consensus2.1.out new file mode 100644 index 0000000..65ec852 --- /dev/null +++ b/test/consensus2.1.out @@ -0,0 +1,10 @@ +>1 +CTACCATATGTGACATATAAAAAAGAACATAACCTACGTATCAACTAAAGTGGTTGTTA +>2 +CCTACCATATGTGACATATAAAAAAGAACATAACCTACGTATCAACTAAAGTGGTTGTTA +>3 +CCCTACCATATGTGACATATAAAAAAGAACATAACCTACGTATCAACTAAAGTGGTTGTT +A +>4 +CCCCTACCATATGTGACATATAAAAAAGAACATAACCTACGTATCAACTAAAGTGGTTGT +TA diff --git a/test/consensus2.2.out b/test/consensus2.2.out new file mode 100644 index 0000000..2040354 --- /dev/null +++ b/test/consensus2.2.out @@ -0,0 +1,12 @@ +>1 +CTACCATATGTGACATATAAAAAAGAACATAACCTACGTATCAACTAAAGTGGTTGTTCA +A +>2 +CCTACCATATGTGACATATAAAAAAGAACATAACCTACGTATCAACTAAAGTGGTTGTTC +AA +>3 +CCCTACCATATGTGACATATAAAAAAGAACATAACCTACGTATCAACTAAAGTGGTTGTT +CAA +>4 +CCCCTACCATATGTGACATATAAAAAAGAACATAACCTACGTATCAACTAAAGTGGTTGT +TCAA diff --git a/test/consensus2.fa b/test/consensus2.fa new file mode 100644 index 0000000..9f3522f --- /dev/null +++ b/test/consensus2.fa @@ -0,0 +1,10 @@ +>1 +CTACCATATGTGACATATAAAAAAGAACATAACCTACGTATCAACTAAAGTGGTTGTTC +>2 +CCTACCATATGTGACATATAAAAAAGAACATAACCTACGTATCAACTAAAGTGGTTGTTC +>3 +CCCTACCATATGTGACATATAAAAAAGAACATAACCTACGTATCAACTAAAGTGGTTGTT +C +>4 +CCCCTACCATATGTGACATATAAAAAAGAACATAACCTACGTATCAACTAAAGTGGTTGT +TC diff --git a/test/consensus2.vcf b/test/consensus2.vcf new file mode 100644 index 0000000..ca4c059 --- /dev/null +++ b/test/consensus2.vcf @@ -0,0 +1,9 @@ +##fileformat=VCFv4.2 +##FORMAT= +##INFO= +##ALT= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA001 +1 59 . C a,Caa . PASS . GT 1|2 +2 60 . C a,Caa . PASS . GT 1|2 +3 61 . C a,Caa . PASS . GT 1|2 +4 62 . C a,Caa . PASS . GT 1|2 diff --git a/test/convert.23andme b/test/convert.23andme new file mode 100644 index 0000000..8439bb2 --- /dev/null +++ b/test/convert.23andme @@ -0,0 +1,28 @@ +# rsid chromosome position genotype +rs001 1 2 AA +rs002 1 10 AG +rs003 1 14 AG +rs004 1 24 TC +rs005 1 44 CG +rs006 1 53 GG +rs007 1 60 GG +rs008 1 62 CC +rs009 1 75 AA +rs010 1 80 GG +rs011 1 89 TT +rs012 1 96 -- +rs013 1 99 CC +rs014 1 102 GG +rs015 1 112 TT +rs016 2 5 CC +rs017 2 11 CT +rs018 2 16 CC +rs019 2 20 GG +rs020 2 33 CT +rs021 2 39 AA +rs022 2 44 CC +rs023 2 48 CC +rs024 2 55 AA +rs025 2 59 CT +rs026 Y 12 T +rs027 Y 20 C diff --git a/test/convert.23andme.vcf b/test/convert.23andme.vcf new file mode 100644 index 0000000..c936a42 --- /dev/null +++ b/test/convert.23andme.vcf @@ -0,0 +1,34 @@ +##fileformat=VCFv4.2 +##FILTER= +##contig= +##contig= +##contig= +##FORMAT= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT SAMPLE1 +1 2 rs001 A . . . . GT 0/0 +1 10 rs002 G A . . . GT 1/0 +1 14 rs003 A G . . . GT 0/1 +1 24 rs004 T C . . . GT 0/1 +1 44 rs005 C G . . . GT 0/1 +1 53 rs006 G . . . . GT 0/0 +1 60 rs007 A G . . . GT 1/1 +1 62 rs008 C . . . . GT 0/0 +1 75 rs009 A . . . . GT 0/0 +1 80 rs010 G . . . . GT 0/0 +1 89 rs011 C T . . . GT 1/1 +1 96 rs012 T . . . . GT . +1 99 rs013 C . . . . GT 0/0 +1 102 rs014 T G . . . GT 1/1 +1 112 rs015 T . . . . GT 0/0 +2 5 rs016 C . . . . GT 0/0 +2 11 rs017 T C . . . GT 1/0 +2 16 rs018 C . . . . GT 0/0 +2 20 rs019 G . . . . GT 0/0 +2 33 rs020 T C . . . GT 1/0 +2 39 rs021 A . . . . GT 0/0 +2 44 rs022 C . . . . GT 0/0 +2 48 rs023 C . . . . GT 0/0 +2 55 rs024 C A . . . GT 1/1 +2 59 rs025 C T . . . GT 0/1 +Y 12 rs026 G T . . . GT 1 +Y 20 rs027 C . . . . GT 0 diff --git a/test/convert.gs.gt.gen b/test/convert.gs.gt.gen new file mode 100644 index 0000000..e209a57 --- /dev/null +++ b/test/convert.gs.gt.gen @@ -0,0 +1,32 @@ +X:2698560_G_A X:2698560_G_A 2698560 G A 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 +X:2698630_A_G X:2698630_A_G 2698630 A G 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 +X:2698758_CAA_C X:2698758_CAA_C 2698758 CAA C 1 0 0 0 1 0 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 +X:2698769_AAG_A X:2698769_AAG_A 2698769 AAG A 0 1 0 0 0 1 0 1 0 0 1 0 0 1 0 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 +X:2698789_C_G X:2698789_C_G 2698789 C G 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 +X:2698822_A_C X:2698822_A_C 2698822 A C 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 +X:2698831_G_A X:2698831_G_A 2698831 G A 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 +X:2698889_T_C X:2698889_T_C 2698889 T C 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 +X:2698923_G_A X:2698923_G_A 2698923 G A 0 1 0 0 1 0 0 1 0 0 1 0 0 1 0 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 +X:2698953_A_AGG X:2698953_A_AGG 2698953 A AGG 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 +X:2698954_G_A X:2698954_G_A 2698954 G A 0 1 0 0 0 1 0 1 0 0 1 0 0 1 0 1 0 0 1 0 0 0 1 0 1 0 0 1 0 0 +X:2699002_C_A X:2699002_C_A 2699002 C A 1 0 0 1 0 0 0.33 0.33 0.33 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 +X:2699025_T_C X:2699025_T_C 2699025 T C 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 +X:2699091_G_A X:2699091_G_A 2699091 G A 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 +X:2699187_T_C X:2699187_T_C 2699187 T C 1 0 0 1 0 0 0 1 0 1 0 0 0 1 0 0 1 0 0 1 0 1 0 0 1 0 0 0 1 0 +X:2699188_G_C X:2699188_G_C 2699188 G C 1 0 0 1 0 0 0 1 0 1 0 0 0 1 0 0 1 0 0 1 0 1 0 0 1 0 0 0 1 0 +X:2699189_T_C X:2699189_T_C 2699189 T C 1 0 0 1 0 0 0 1 0 1 0 0 0 1 0 0 1 0 0 1 0 1 0 0 1 0 0 0 1 0 +X:2699217_C_T X:2699217_C_T 2699217 C T 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 +X:2699246_C_A X:2699246_C_A 2699246 C A 0 1 0 0 0 1 0 1 0 0 0 1 0 1 0 0 1 0 1 0 0 0 1 0 1 0 0 0 1 0 +X:2699275_T_G X:2699275_T_G 2699275 T G 1 0 0 1 0 0 0 1 0 1 0 0 0 1 0 0 0 1 0 1 0 1 0 0 1 0 0 0 1 0 +X:2699350_A_T X:2699350_A_T 2699350 A T 1 0 0 1 0 0 0 1 0 1 0 0 0 1 0 0 1 0 0 1 0 1 0 0 1 0 0 0 1 0 +X:2699360_T_C X:2699360_T_C 2699360 T C 1 0 0 1 0 0 0 1 0 1 0 0 0 1 0 0 1 0 0 1 0 1 0 0 1 0 0 0 1 0 +X:2699450_A_C X:2699450_A_C 2699450 A C 1 0 0 1 0 0 0 1 0 1 0 0 0 1 0 0 1 0 0 1 0 1 0 0 1 0 0 0 1 0 +X:2699507_T_C X:2699507_T_C 2699507 T C 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 +X:2699555_C_A X:2699555_C_A 2699555 C A 1 0 0 0 0 1 0 0 1 1 0 0 0 0 1 0 0 1 0 1 0 0 1 0 1 0 0 0 1 0 +X:2699645_G_T X:2699645_G_T 2699645 G T 1 0 0 0 0 1 1 0 0 1 0 0 1 0 0 1 0 0 1 0 0 0 1 0 1 0 0 1 0 0 +X:2699676_G_A X:2699676_G_A 2699676 G A 1 0 0 1 0 0 0 0 1 1 0 0 0 0 1 0 1 0 0 1 0 1 0 0 1 0 0 0 1 0 +X:2699728_C_T X:2699728_C_T 2699728 C T 1 0 0 1 0 0 1 0 0 1 0 0 1 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GT 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 +X 2699091 . G A . . . GT 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 +X 2699187 . T C . . . GT 0|0 0|0 1|0 0|0 0|1 1|0 1|0 0|0 0|0 0/1 +X 2699188 . G C . . . GT 0|0 0|0 1|0 0|0 0|1 1|0 1|0 0|0 0|0 0|1 +X 2699189 . T C . . . GT 0|0 0|0 1|0 0|0 0|1 1|0 1|0 0|0 0|0 0|1 +X 2699217 . C T . . . GT 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 +X 2699246 . C A . . . GT 1|0 1|1 0|1 1|1 1|0 0|1 0|0 0|1 0|0 1|0 +X 2699275 . T G . . . GT 0|0 0|0 1|0 0|0 0|1 1|1 1|0 0|0 0|0 0|1 +X 2699350 . A T . . . GT 0|0 0|0 1|0 0|0 0|1 1|0 1|0 0|0 0|0 0|1 +X 2699360 . T C . . . GT 0|0 0|0 1|0 0|0 0|1 1|0 1|0 0|0 0|0 0|1 +X 2699450 . A C . . . GT 0|0 0|0 1|0 0|0 0|1 1|0 1|0 0|0 0|0 0|1 +X 2699507 . T C . . . GT 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 +X 2699555 . C A . . . GT 0 1 1 0 1 1|1 1|0 0|1 0|0 0|1 +X 2699645 . G T . . . GT 0 1 0 0 0 0|0 0|0 0|1 0|0 0|0 +X 2699676 . G A . . . GT 0 0 1 0 1 1|0 1|0 0|0 0|0 0|1 +X 2699728 . C T . . . GT 0 0 0 0 0 0|0 0|0 0|0 0|0 0|0 +X 2699775 . C A . . . GT 0 0 0 0 0 0|0 0|0 0|0 0|0 0|0 +X 2699898 . C CT . . . GT 0 0 1 0 1 1|0 1|0 0|0 0|0 0|1 +X 2699968 . A G . . . GT . 0 0 1 0 0|1 0|0 0|0 0|1 1|0 +X 2699970 . T C . . . GT 0 0 0 0 0 0|0 0|0 0|0 0|0 0|0 +X 2699990 . C . . END=2700054 GT 0|0 0|0 1|0 0|0 0|1 1|0 1|0 0|0 0|0 0|1 diff --git a/test/convert.gt.vcf b/test/convert.gt.vcf new file mode 100644 index 0000000..7c719a2 --- /dev/null +++ b/test/convert.gt.vcf @@ -0,0 +1,43 @@ +##fileformat=VCFv4.1 +##FILTER= +##FORMAT= +##contig= +##bcftools_normVersion=1.2+htslib-1.2.1 +##bcftools_normCommand=norm -m - convert.vcf +##bcftools_annotateVersion=1.2+htslib-1.2.1 +##bcftools_annotateCommand=annotate -x FORMAT,QUAL +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA00001 NA00002 NA00003 NA00004 NA00005 NA00006 NA00007 NA00008 NA00009 NA00010 +X 2698560 . G A . . . GT 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 +X 2698630 . A G . . . GT 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 +X 2698758 . CAA C . . . GT 0|0 0|1 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 +X 2698769 . AAG A . . . GT 1|0 1|1 0|1 1|0 1|0 0|0 0|0 0|0 0|0 0|0 +X 2698770 . AG A . . . GT 0|0 0|1 0|0 0|0 1|0 0|0 0|0 0|0 0|0 0|0 +X 2698770 . AG AAGG . . . GT 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 +X 2698789 . C G . . . GT 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 +X 2698822 . A C . . . GT 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 +X 2698831 . G A . . . GT 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 +X 2698889 . T C . . . GT 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 +X 2698923 . G A . . . GT 1|0 0|1 0|1 1|0 1|0 0|0 0|0 0|0 0|0 0|0 +X 2698953 . A AGG . . . GT 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 +X 2698954 . G A . . . GT 1|0 1|1 0|1 1|0 1|0 0|0 0|0 0|1 0|0 0|0 +X 2699002 . C A . . . GT 0|0 0|0 .|. 0|0 0|0 0|0 0|0 0|0 0|0 0|0 +X 2699025 . T C . . . GT 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 +X 2699091 . G A . . . GT 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 +X 2699187 . T C . . . GT 0|0 0|0 1|0 0|0 0|1 1|0 1|0 0|0 0|0 0/1 +X 2699188 . G C . . . GT 0|0 0|0 1|0 0|0 0|1 1|0 1|0 0|0 0|0 0|1 +X 2699189 . T C . . . GT 0|0 0|0 1|0 0|0 0|1 1|0 1|0 0|0 0|0 0|1 +X 2699217 . C T . . . GT 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 +X 2699246 . C A . . . GT 1|0 1|1 0|1 1|1 1|0 0|1 0|0 0|1 0|0 1|0 +X 2699275 . T G . . . GT 0|0 0|0 1|0 0|0 0|1 1|1 1|0 0|0 0|0 0|1 +X 2699350 . A T . . . GT 0|0 0|0 1|0 0|0 0|1 1|0 1|0 0|0 0|0 0|1 +X 2699360 . T C . . . GT 0|0 0|0 1|0 0|0 0|1 1|0 1|0 0|0 0|0 0|1 +X 2699450 . A C . . . GT 0|0 0|0 1|0 0|0 0|1 1|0 1|0 0|0 0|0 0|1 +X 2699507 . T C . . . GT 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 0|0 +X 2699555 . C A . . . GT 0 1 1 0 1 1|1 1|0 0|1 0|0 0|1 +X 2699645 . G T . . . GT 0 1 0 0 0 0|0 0|0 0|1 0|0 0|0 +X 2699676 . G A . . . GT 0 0 1 0 1 1|0 1|0 0|0 0|0 0|1 +X 2699728 . C T . . . GT 0 0 0 0 0 0|0 0|0 0|0 0|0 0|0 +X 2699775 . C A . . . GT 0 0 0 0 0 0|0 0|0 0|0 0|0 0|0 +X 2699898 . C CT . . . GT 0 0 1 0 1 1|0 1|0 0|0 0|0 0|1 +X 2699968 . A G . . . GT . 0 0 1 0 0|1 0|0 0|0 0|1 1|0 +X 2699970 . T C . . . GT 0 0 0 0 0 0|0 0|0 0|0 0|0 0|0 diff --git a/test/convert.gvcf.out b/test/convert.gvcf.out new file mode 100644 index 0000000..d2c0fc9 --- /dev/null +++ b/test/convert.gvcf.out @@ -0,0 +1,408 @@ +##fileformat=VCFv4.1 +##FILTER= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##FILTER= +##FILTER= +##FILTER= +##FILTER= +##FILTER= +##FILTER= +##FILTER= +##contig= +##SnvTheta=0.001 +##IndelTheta=0.0001 +##MaxDepth_1=114.18 +##MaxDepth_10=131.73 +##MaxDepth_11=117.27 +##MaxDepth_12=116.97 +##MaxDepth_13=102.24 +##MaxDepth_14=101.55 +##MaxDepth_15=95.22 +##MaxDepth_16=111.33 +##MaxDepth_17=112.59 +##MaxDepth_18=121.86 +##MaxDepth_19=111.12 +##MaxDepth_2=121.83 +##MaxDepth_20=111.24 +##MaxDepth_21=98.43 +##MaxDepth_22=76.23 +##MaxDepth_3=120.09 +##MaxDepth_4=124.50 +##MaxDepth_5=119.82 +##MaxDepth_6=122.22 +##MaxDepth_7=120.27 +##MaxDepth_8=120.45 +##MaxDepth_9=102.48 +##MaxDepth_M=7005.66 +##MaxDepth_X=61.05 +##MaxDepth_Y=37.17 +##FILTER= +##gvcftools_version="0.16" +##FILTER= +##FORMAT= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT SAMPLE99 +22 1 . N . 0 LowGQX END=9;BLOCKAVG_min30p3a GT:GQX:DP:DPF .:.:0:0 +22 10 . C . 0 LowGQX END=20;BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:5:2:0 +22 21 . C . 0 LowGQX END=26;BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:10:4:0 +22 27 . C . 0 LowGQX END=42;BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:15:6:0 +22 43 . G . 0 LowGQX END=50;BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:21:8:0 +22 51 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:30:11:0 +22 52 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:30:11:0 +22 53 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:30:11:0 +22 54 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:30:11:0 +22 55 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:30:11:0 +22 56 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:42:15:0 +22 57 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:42:15:0 +22 58 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:42:15:0 +22 59 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:42:15:0 +22 60 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:42:15:0 +22 61 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:42:15:0 +22 62 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:42:15:0 +22 63 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:42:15:0 +22 64 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:42:15:0 +22 65 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:42:15:0 +22 66 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:42:15:0 +22 67 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:42:15:0 +22 68 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:42:15:0 +22 69 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:42:15:0 +22 70 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:42:15:0 +22 71 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:42:15:0 +22 72 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:42:15:0 +22 73 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:54:19:0 +22 74 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:54:19:0 +22 75 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:54:19:0 +22 76 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:54:19:0 +22 77 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:54:19:0 +22 78 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:54:19:0 +22 79 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:54:19:0 +22 80 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:54:19:0 +22 81 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:54:19:0 +22 82 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:54:19:0 +22 83 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:54:19:0 +22 84 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:54:19:0 +22 85 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:54:19:0 +22 86 . G C 23 LowGQX SNVSB=0;SNVHPOL=2 GT:GQ:GQX:DP:DPF:AD 0/1:56:23:22:0:16,6 +22 87 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:69:24:0 +22 88 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:69:24:0 +22 89 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:69:24:0 +22 90 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:69:24:0 +22 91 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:69:24:0 +22 92 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:69:24:0 +22 93 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:69:24:0 +22 94 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:69:24:0 +22 95 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:69:24:0 +22 96 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:69:24:0 +22 97 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:69:24:0 +22 98 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:69:24:0 +22 99 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:69:24:0 +22 100 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:69:24:0 +22 101 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:69:24:0 +22 102 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 +22 103 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 +22 104 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 +22 105 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 +22 106 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 +22 107 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 +22 108 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 +22 109 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 +22 110 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 +22 111 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 +22 112 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 +22 113 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 +22 114 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 +22 115 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 +22 116 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 +22 117 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 +22 118 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 +22 119 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 +22 120 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 +22 121 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 +22 122 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 +22 123 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 +22 124 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 +22 125 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 +22 126 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 +22 127 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 +22 128 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 +22 129 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 +22 130 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 +22 131 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 +22 132 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 +22 133 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 +22 134 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 +22 135 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 +22 136 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 +22 137 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 +22 138 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 +22 139 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 +22 140 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:84:29:0 +22 141 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 +22 142 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 +22 143 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 +22 144 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 +22 145 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 +22 146 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 +22 147 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 +22 148 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 +22 149 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 +22 150 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 +22 151 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 +22 152 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 +22 153 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 +22 154 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 +22 155 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 +22 156 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 +22 157 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 +22 158 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 +22 159 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 +22 160 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 +22 161 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 +22 162 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 +22 163 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 +22 164 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 +22 165 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 +22 166 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 +22 167 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 +22 168 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 +22 169 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 +22 170 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 +22 171 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 +22 172 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 +22 173 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 +22 174 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 +22 175 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 +22 176 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 +22 177 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 +22 178 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 +22 179 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 +22 180 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 +22 181 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 +22 182 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 +22 183 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 +22 184 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 +22 185 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:90:31:0 +22 186 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:93:32:2 +22 187 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:93:32:2 +22 188 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:102:35:0 +22 189 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:102:35:0 +22 190 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:102:35:0 +22 191 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:102:35:0 +22 192 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:102:35:0 +22 193 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:102:35:0 +22 194 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:102:35:0 +22 195 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:102:35:0 +22 196 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:102:35:0 +22 197 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:102:35:0 +22 198 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:102:35:0 +22 199 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:102:35:0 +22 200 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:102:35:0 +22 201 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:102:35:0 +22 202 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:102:35:0 +22 203 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:102:35:0 +22 204 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:102:35:0 +22 205 . T . 0 PASS . GT:GQX:DP:DPF 0/0:72:36:0 +22 206 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:87:30:0 +22 207 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:87:30:0 +22 208 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:87:30:0 +22 209 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:87:30:0 +22 210 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:87:30:0 +22 211 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:87:30:0 +22 212 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:87:30:0 +22 213 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:87:30:0 +22 214 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:87:30:0 +22 215 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:87:30:0 +22 216 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:87:30:0 +22 217 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:87:30:0 +22 218 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:87:30:0 +22 219 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:87:30:0 +22 220 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:87:30:0 +22 221 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:87:30:0 +22 222 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:87:30:0 +22 223 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:87:30:0 +22 224 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:87:30:0 +22 225 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:87:30:0 +22 226 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:87:30:0 +22 227 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:87:30:0 +22 228 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:87:30:0 +22 229 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:87:30:0 +22 230 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:87:30:0 +22 231 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:87:30:0 +22 232 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:66:23:0 +22 233 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:66:23:0 +22 234 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:66:23:0 +22 235 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:66:23:0 +22 236 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:66:23:0 +22 237 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:66:23:0 +22 238 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:66:23:0 +22 239 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:66:23:0 +22 240 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:66:23:0 +22 241 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:66:23:0 +22 242 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:66:23:0 +22 243 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:66:23:0 +22 244 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:66:23:0 +22 245 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:66:23:0 +22 246 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:66:23:0 +22 247 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:66:23:0 +22 248 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:66:23:0 +22 249 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:66:23:0 +22 250 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:87:30:0 +22 251 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:87:30:0 +22 252 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:87:30:0 +22 253 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:87:30:0 +22 254 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:87:30:0 +22 255 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:87:30:0 +22 256 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:87:30:0 +22 257 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:87:30:0 +22 258 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:114:39:0 +22 259 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:114:39:0 +22 260 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:114:39:0 +22 261 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:114:39:0 +22 262 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:114:39:0 +22 263 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:114:39:0 +22 264 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:114:39:0 +22 265 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:114:39:0 +22 266 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:114:39:0 +22 267 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:114:39:0 +22 268 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:114:39:0 +22 269 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:114:39:0 +22 270 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:150:51:0 +22 271 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:150:51:0 +22 272 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:150:51:0 +22 273 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:150:51:0 +22 274 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:150:51:0 +22 275 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:150:51:0 +22 276 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:150:51:0 +22 277 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:150:51:0 +22 278 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:150:51:0 +22 279 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:150:51:0 +22 280 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:166:63:0 +22 281 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:166:63:0 +22 282 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:166:63:0 +22 283 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:166:63:0 +22 284 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:166:63:0 +22 285 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:166:63:0 +22 286 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:166:63:0 +22 287 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:166:63:0 +22 288 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:166:63:0 +22 289 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:166:63:0 +22 290 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:166:63:0 +22 291 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:166:63:0 +22 292 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:166:63:0 +22 293 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:166:63:0 +22 294 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:166:63:0 +22 295 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:166:63:0 +22 296 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:166:63:0 +22 297 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:166:63:0 +22 298 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:166:63:0 +22 299 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:166:63:0 +22 300 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:166:63:0 +22 301 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:166:63:0 +22 302 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:166:63:0 +22 303 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:166:63:0 +22 304 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:166:63:0 +22 305 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:166:63:0 +22 306 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:166:63:0 +22 307 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:166:63:0 +22 308 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:166:63:0 +22 309 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:166:63:0 +22 310 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:166:63:0 +22 311 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:166:63:0 +22 312 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:166:63:0 +22 313 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:166:63:0 +22 314 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:166:63:0 +22 315 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:220:74:0 +22 316 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:220:74:0 +22 317 . T . 0 HighDepth END=342;BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:229:77:0 +22 343 . T . 0 HighDepth END=377;BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:241:81:0 +22 378 . T . 0 HighDepth END=384;BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:200:75:0 +22 385 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:217:73:0 +22 386 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:217:73:0 +22 387 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:217:73:0 +22 388 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:217:73:0 +22 389 . C . 0 HighDepth END=390;BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:223:75:0 +22 391 . T . 0 PASS . GT:GQX:DP:DPF 0/0:223:75:1 +22 392 . T . 0 HighDepth END=397;BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:223:75:0 +22 398 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:178:60:0 +22 399 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:178:60:0 +22 400 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:178:60:0 +22 401 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:178:60:0 +22 402 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:178:60:0 +22 403 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:178:60:0 +22 404 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:178:60:0 +22 405 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:178:60:0 +22 406 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:178:60:0 +22 407 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:178:60:0 +22 408 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:178:60:0 +22 409 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:178:60:0 +22 410 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:178:60:0 +22 411 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:178:60:0 +22 412 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:178:60:0 +22 413 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:178:60:0 +22 414 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:178:60:0 +22 415 . G . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:178:60:0 +22 416 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:178:60:0 +22 417 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:178:60:0 +22 418 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:178:60:0 +22 419 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:178:60:0 +22 420 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:178:60:0 +22 421 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:142:54:0 +22 422 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:142:54:0 +22 423 . C . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:142:54:0 +22 424 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:142:54:0 +22 425 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:142:54:0 +22 426 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:142:54:0 +22 427 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:142:54:0 +22 428 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:142:54:0 +22 429 . T . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:142:54:0 +22 430 . A . 0 PASS BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:142:54:0 +22 431 . 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AG A,AAGG 999 . . GT:PL:GP 0|0:0,12,103,12,103,103:0.925,0.0717,0,0.0033,0,0 0|1:0,3,21,3,21,21:0.4944,0.368,0.0018,0.1343,0.0013,0.0002 0|0:0,0,0,0,0,0:0.5458,0.4085,0,0.0457,0,0 0|0:0,3,36,3,36,36:0.8126,0.1758,0,0.0116,0,0 1|0:37,0,86,49,92,130:0,1,0,0,0,0 0|0:0,15,125,15,125,125:1,0,0,0,0,0 0|0:0,9,105,9,105,105:1,0,0,0,0,0 0|0:0,15,109,15,109,109:0.9964,0.0034,0,0.0002,0,0 0|0:0,15,137,15,137,137:1,0,0,0,0,0 0|0:0,33,215,33,215,215:1,0,0,0,0,0 +X 2698789 . C G 153 . . GT:PL:GP 0|0:0,21,152:1,0,0 0|0:0,21,131:1,0,0 0|0:0,12,113:1,0,0 0|0:0,12,104:1,0,0 0|0:0,21,137:1,0,0 0|0:0,15,118:0.9999,0.0001,0 0|0:0,15,111:1,0,0 0|0:0,24,152:1,0,0 0|0:0,18,147:1,0,0 0|0:0,33,183:1,0,0 +X 2698822 . A C 85.2 . . GT:PL:GP 0|0:0,21,167:1,0,0 0|0:0,21,171:1,0,0 0|0:0,21,158:1,0,0 0|0:0,18,154:1,0,0 0|0:0,15,135:1,0,0 0|0:0,15,132:1,0,0 0|0:0,21,168:1,0,0 0|0:0,21,175:1,0,0 0|0:0,15,142:1,0,0 0|0:0,21,172:1,0,0 +X 2698831 . G A 303 . . GT:PL:GP 0|0:0,15,129:1,0,0 0|0:0,27,179:1,0,0 0|0:0,24,196:1,0,0 0|0:0,21,158:1,0,0 0|0:0,18,154:1,0,0 0|0:0,12,112:1,0,0 0|0:0,24,162:1,0,0 0|0:0,21,168:1,0,0 0|0:0,9,95:1,0,0 0|0:0,21,164:1,0,0 +X 2698889 . T C 74.4 . . GT:PL:GP 0|0:0,27,193:1,0,0 0|0:0,45,255:1,0,0 0|0:0,21,190:1,0,0 0|0:0,36,254:1,0,0 0|0:0,30,226:1,0,0 0|0:0,36,253:1,0,0 0|0:0,18,156:1,0,0 0|0:0,9,87:1,0,0 0|0:0,9,98:1,0,0 0|0:0,24,205:1,0,0 +X 2698923 . G A 999 . . GT:PL:GP 1|0:62,0,133:0,1,0 0|1:164,0,91:0,1,0 0|1:35,0,73:0,1,0 1|0:91,0,108:0,1,0 1|0:67,0,71:0,1,0 0|0:0,30,187:1,0,0 0|0:0,9,73:1,0,0 0|0:0,12,99:1,0,0 0|0:0,18,153:1,0,0 0|0:0,18,138:1,0,0 +X 2698953 . A AGG 267 . . GT:PL:GP 0|0:0,27,111:1,0,0 0|0:0,33,124:1,0,0 0|0:0,12,62:1,0,0 0|0:0,15,86:1,0,0 0|0:0,12,58:1,0,0 0|0:0,15,69:1,0,0 0|0:0,6,34:1,0,0 0|0:0,18,83:1,0,0 0|0:0,18,80:1,0,0 0|0:0,15,74:1,0,0 +X 2698954 . G A 999 . . GT:PL:GP 1|0:69,0,139:0,1,0 1|1:199,24,0:0,0,1 0|1:15,0,82:0,1,0 1|0:32,0,76:0,1,0 1|0:16,0,80:0,1,0 0|0:0,15,131:1,0,0 0|0:0,6,58:1,0,0 0|1:99,0,39:0,1,0 0|0:0,18,163:1,0,0 0|0:0,15,136:1,0,0 +X 2699002 . C A 65.1 . . GT:PL:GP 0|0:0,18,144:1,0,0 0|0:0,12,115:1,0,0 .|.:0,12,120:1,0,0 0|0:0,15,131:1,0,0 0|0:0,6,29:1,0,0 0|0:0,9,95:1,0,0 0|0:0,9,79:1,0,0 0|0:0,24,188:1,0,0 0|0:0,15,124:1,0,0 0|0:0,9,93:1,0,0 +X 2699025 . T C 44.9 . . GT:PL:GP 0|0:0,24,189:1,0,0 0|0:0,12,98:1,0,0 0|0:0,15,130:1,0,0 0|0:0,15,113:1,0,0 0|0:0,6,63:1,0,0 0|0:0,24,198:1,0,0 0|0:0,12,92:1,0,0 0|0:0,24,197:1,0,0 0|0:0,9,97:1,0,0 0|0:0,12,108:1,0,0 +X 2699091 . G A 45 . . GT:PL:GP 0|0:0,18,162:1,0,0 0|0:0,21,153:1,0,0 0|0:0,12,101:1,0,0 0|0:0,12,97:1,0,0 0|0:0,24,188:1,0,0 0|0:0,24,194:1,0,0 0|0:0,15,127:1,0,0 0|0:0,21,169:1,0,0 0|0:0,15,129:1,0,0 0|0:0,21,171:1,0,0 +X 2699187 . T C 999 . . GT:PL:GP 0|0:0,24,200:1,0,0 0|0:0,24,191:1,0,0 1|0:48,0,85:0,1,0 0|0:0,15,145:1,0,0 0|1:58,0,45:0,1,0 1|0:61,0,50:0,1,0 1|0:22,0,51:0,1,0 0|0:0,27,211:1,0,0 0|0:0,9,96:0.9999,0.0001,0 0/1:23,0,160:0,1,0 +X 2699188 . G C 999 . . GT:PL:GP 0|0:0,24,194:1,0,0 0|0:0,24,167:1,0,0 1|0:48,0,78:0,1,0 0|0:0,15,131:1,0,0 0|1:63,0,40:0,1,0 1|0:50,0,44:0,1,0 1|0:22,0,48:0,1,0 0|0:0,27,212:1,0,0 0|0:0,9,87:0.9999,0.0001,0 0|1:23,0,154:0,1,0 +X 2699189 . T C 999 . . GT:PL:GP 0|0:0,24,199:1,0,0 0|0:0,24,176:1,0,0 1|0:44,0,87:0,1,0 0|0:0,15,136:1,0,0 0|1:62,0,46:0,1,0 1|0:61,0,46:0,1,0 1|0:22,0,49:0,1,0 0|0:0,27,212:1,0,0 0|0:0,9,93:0.9999,0.0001,0 0|1:23,0,164:0,1,0 +X 2699217 . C T 60.3 . . GT:PL:GP 0|0:0,18,158:1,0,0 0|0:0,18,119:1,0,0 0|0:0,21,152:1,0,0 0|0:0,21,162:1,0,0 0|0:0,12,102:1,0,0 0|0:0,18,144:1,0,0 0|0:0,12,108:1,0,0 0|0:0,18,146:1,0,0 0|0:0,12,98:1,0,0 0|0:0,18,155:1,0,0 +X 2699246 . C A 999 . . GT:PL:GP 1|0:128,0,15:0,0.9998,0.0002 1|1:147,21,0:0,0.0001,0.9999 0|1:130,0,5:0,0.9977,0.0023 1|1:237,33,0:0,0,1 1|0:45,0,75:0,1,0 0|1:145,0,49:0,1,0 0|0:0,15,109:1,0,0 0|1:13,0,63:0.0002,0.9998,0 0|0:0,30,178:0.9953,0.0047,0 1|0:120,0,57:0,1,0 +X 2699275 . T G 999 . . GT:PL:GP 0|0:0,18,165:0.9998,0.0002,0 0|0:0,18,152:1,0,0 1|0:0,9,95:0.0023,0.9977,0 0|0:0,33,239:1,0,0 0|1:125,0,40:0,1,0 1|1:205,27,0:0,0,1 1|0:69,0,43:0,1,0 0|0:0,15,139:1,0,0 0|0:0,30,219:1,0,0 0|1:96,0,54:0,1,0 +X 2699350 . A T 999 . . GT:PL:GP 0|0:0,27,206:1,0,0 0|0:0,15,139:1,0,0 1|0:54,0,25:0,1,0 0|0:0,12,117:0.9996,0.0004,0 0|1:79,0,73:0,1,0 1|0:48,0,82:0,1,0 1|0:68,0,45:0,1,0 0|0:0,30,216:1,0,0 0|0:0,27,224:1,0,0 0|1:48,0,80:0,1,0 +X 2699360 . T C 999 . . GT:PL:GP 0|0:0,21,184:1,0,0 0|0:0,15,133:1,0,0 1|0:53,0,21:0,1,0 0|0:0,12,114:0.9996,0.0004,0 0|1:20,0,66:0,1,0 1|0:40,0,93:0,1,0 1|0:52,0,66:0,1,0 0|0:0,30,220:1,0,0 0|0:0,21,191:1,0,0 0|1:20,0,83:0,1,0 +X 2699450 . A C 999 . . GT:PL:GP 0|0:0,12,124:1,0,0 0|0:0,6,55:0.9976,0.0024,0 1|0:99,0,42:0,1,0 0|0:0,21,186:0.9999,0.0001,0 0|1:64,0,100:0,1,0 1|0:38,0,177:0,1,0 1|0:16,0,103:0,1,0 0|0:0,24,202:1,0,0 0|0:0,12,119:1,0,0 0|1:75,0,115:0,1,0 +X 2699507 . T C 195 . . GT:PL:GP 0|0:0,15,133:1,0,0 0|0:0,12,122:1,0,0 0|0:0,6,60:1,0,0 0|0:0,18,123:1,0,0 0|0:0,15,145:1,0,0 0|0:0,21,173:1,0,0 0|0:0,21,178:1,0,0 0|0:0,24,200:1,0,0 0|0:0,12,125:1,0,0 0|0:0,24,189:1,0,0 +X 2699555 . C A 999 . . GT:PL:GP 0:0,156:1,0 1:58,19:0,1 1:51,0:0,1 0:0,91:1,0 1:89,0:0,1 1|1:132,15,0:0,0,1 1|0:99,0,68:0,1,0 0|1:101,0,101:0,1,0 0|0:0,18,161:0.9998,0.0002,0 0|1:118,0,72:0,1,0 +X 2699645 . G T 999 . . GT:PL:GP 0:0,95:1,0 1:49,0:0,1 0:0,58:1,0 0:0,64:1,0 0:0,113:1,0 0|0:0,18,158:1,0,0 0|0:0,18,146:1,0,0 0|1:68,0,136:0,1,0 0|0:0,30,210:1,0,0 0|0:0,27,186:1,0,0 +X 2699676 . G A 999 . . GT:PL:GP 0:0,84:1,0 0:0,87:1,0 1:35,0:0,1 0:0,28:1,0 1:114,0:0,1 1|0:99,0,72:0,1,0 1|0:48,0,89:0,1,0 0|0:0,18,155:1,0,0 0|0:0,24,191:1,0,0 0|1:99,0,61:0,1,0 +X 2699728 . C T 69.7 . . GT:PL:GP 0:0,58:1,0 0:0,64:1,0 0:0,33:1,0 0:0,69:1,0 0:0,81:1,0 0|0:0,27,183:1,0,0 0|0:0,45,220:1,0,0 0|0:0,30,161:1,0,0 0|0:0,15,110:1,0,0 0|0:0,21,156:1,0,0 +X 2699775 . C A 71.1 . . GT:PL:GP 0:0,62:1,0 0:0,101:1,0 0:0,130:1,0 0:0,141:1,0 0:0,54:1,0 0|0:0,30,203:1,0,0 0|0:0,39,208:1,0,0 0|0:0,30,177:1,0,0 0|0:0,18,132:1,0,0 0|0:0,15,103:1,0,0 +X 2699898 . C CT 999 . . GT:PL:GP 0:0,32:1,0 0:0,11:1,0 1:11,0:0,1 0:0,11:1,0 1:31,0:0,1 1|0:11,0,24:0.0438,0.9562,0 1|0:8,0,17:0,1,0 0|0:0,33,72:1,0,0 0|0:0,27,69:1,0,0 0|1:11,4,12:0.0003,0.9997,0 +X 2699968 . A G 999 . . GT:PL:GP .:0,84:1,0 0:0,32:1,0 0:0,57:1,0 1:131,0:0,1 0:0,66:1,0 0|1:89,0,44:0,1,0 0|0:0,18,157:1,0,0 0|0:0,45,255:1,0,0 0|1:75,0,109:0,1,0 1|0:98,0,62:0,1,0 +X 2699970 . T C 55.3 . . GT:PL:GP 0:0,68:1,0 0:0,34:1,0 0:0,32:1,0 0:0,162:1,0 0:0,63:1,0 0|0:0,15,149:1,0,0 0|0:0,21,181:1,0,0 0|0:0,45,255:1,0,0 0|0:0,27,207:1,0,0 0|0:0,24,196:1,0,0 diff --git a/test/csq.1.out b/test/csq.1.out new file mode 100644 index 0000000..d03fdac --- /dev/null +++ b/test/csq.1.out @@ -0,0 +1,99 @@ +90 C T 5_prime_utr|XYZ|ENST00000000001|protein_coding +90 C T 5_prime_utr|XYZ|ENST00000000001|protein_coding + +102 C T synonymous|XYZ|ENST00000000001|protein_coding|+|1Y|102C>T +102 C T synonymous|XYZ|ENST00000000001|protein_coding|+|1Y|102C>T + +103 G A missense|XYZ|ENST00000000001|protein_coding|+|2V>2I|103G>A +103 G A missense|XYZ|ENST00000000001|protein_coding|+|2V>2I|103G>A + +103 G C missense|XYZ|ENST00000000001|protein_coding|+|2V>2L|103G>C +103 G C missense|XYZ|ENST00000000001|protein_coding|+|2V>2L|103G>C + +107 G A missense|XYZ|ENST00000000001|protein_coding|+|3R>3Q|107G>A+108T>A +107 G A missense|XYZ|ENST00000000001|protein_coding|+|3R>3Q|107G>A+108T>A + +108 T A @107,splice_region|XYZ|ENST00000000001|protein_coding +108 T A @107,splice_region|XYZ|ENST00000000001|protein_coding + +121 ACG A inframe_deletion|XYZ|ENST00000000001|protein_coding|+|5TY>5I|121ACG>A+124TA>T,splice_region|XYZ|ENST00000000001|protein_coding +121 ACG A inframe_deletion|XYZ|ENST00000000001|protein_coding|+|5TY>5I|121ACG>A+124TA>T,splice_region|XYZ|ENST00000000001|protein_coding + +124 TA T @121 +124 TA T @121 + +128 T C missense|XYZ|ENST00000000001|protein_coding|+|7V>6A|128T>C+129A>C,splice_region|XYZ|ENST00000000001|protein_coding +128 T C missense|XYZ|ENST00000000001|protein_coding|+|7V>6A|128T>C+129A>C,splice_region|XYZ|ENST00000000001|protein_coding + +129 A C @128,splice_region|XYZ|ENST00000000001|protein_coding +129 A C @128,splice_region|XYZ|ENST00000000001|protein_coding + +140 TA AACG inframe_insertion|XYZ|ENST00000000001|protein_coding|+|8LR>7QRR|140TA>AACG+142C>CC,splice_region|XYZ|ENST00000000001|protein_coding +140 TA AACG inframe_insertion|XYZ|ENST00000000001|protein_coding|+|8LR>7QRR|140TA>AACG+142C>CC,splice_region|XYZ|ENST00000000001|protein_coding + +142 C CC @140,splice_region|XYZ|ENST00000000001|protein_coding +142 C CC @140,splice_region|XYZ|ENST00000000001|protein_coding + +145 AC TA stop_gained|XYZ|ENST00000000001|protein_coding|+|10T>10*|145AC>TA +145 AC TA stop_gained|XYZ|ENST00000000001|protein_coding|+|10T>10*|145AC>TA + +160 TA T *frameshift|XYZ|ENST00000000001|protein_coding|+|12YVRT>12SYV|160TA>T,splice_region|XYZ|ENST00000000001|protein_coding +160 TA T *frameshift|XYZ|ENST00000000001|protein_coding|+|12YVRT>12SYV|160TA>T,splice_region|XYZ|ENST00000000001|protein_coding + +190 C T 3_prime_utr|XYZ|ENST00000000001|protein_coding +190 C T 3_prime_utr|XYZ|ENST00000000001|protein_coding + +97 A C 3_prime_utr|ABC|ENST00000000002|protein_coding +97 A C 3_prime_utr|ABC|ENST00000000002|protein_coding + +105 AC A @121 +105 AC A @121 + +121 AC A frameshift|ABC|ENST00000000002|protein_coding|-|11VVRTY>11*|105AC>A+121AC>A,splice_region|ABC|ENST00000000002|protein_coding +121 AC A frameshift|ABC|ENST00000000002|protein_coding|-|11VVRTY>11*|105AC>A+121AC>A,splice_region|ABC|ENST00000000002|protein_coding + +126 C CTT @127 +126 C CTT @127 + +127 G GG inframe_insertion|ABC|ENST00000000002|protein_coding|-|9T>8TK|126C>CTT+127G>GG +127 G GG inframe_insertion|ABC|ENST00000000002|protein_coding|-|9T>8TK|126C>CTT+127G>GG + +144 TAC T @148 +144 TAC T @148 + +148 TA T inframe_deletion|ABC|ENST00000000002|protein_coding|-|5YV>5T|144TAC>T+148TA>T,splice_region|ABC|ENST00000000002|protein_coding +148 TA T inframe_deletion|ABC|ENST00000000002|protein_coding|-|5YV>5T|144TAC>T+148TA>T,splice_region|ABC|ENST00000000002|protein_coding + +164 T G missense|ABC|ENST00000000002|protein_coding|-|3T>3P|164T>G +164 T G missense|ABC|ENST00000000002|protein_coding|-|3T>3P|164T>G + +165 A C synonymous|ABC|ENST00000000002|protein_coding|-|2R|165A>C +165 A C synonymous|ABC|ENST00000000002|protein_coding|-|2R|165A>C + +169 A G @170 +169 A G @170 + +170 C T missense|ABC|ENST00000000002|protein_coding|-|1V>1T|169A>G+170C>T +170 C T missense|ABC|ENST00000000002|protein_coding|-|1V>1T|169A>G+170C>T + +199 G T 5_prime_utr|ABC|ENST00000000002|protein_coding +199 G T 5_prime_utr|ABC|ENST00000000002|protein_coding + +20 T A non_coding|mir-007||lincRNA +20 T A non_coding|mir-007||lincRNA + +109 ACGTACGT A splice_acceptor|QWRTY|ENST00000000003|protein_coding +109 ACGTACGT A splice_acceptor|QWRTY|ENST00000000003|protein_coding + +113 A T splice_region|QWRTY|ENST00000000003|protein_coding +113 A T splice_region|QWRTY|ENST00000000003|protein_coding + +120 T A intron|QWRTY||protein_coding +120 T A intron|QWRTY||protein_coding + +152 T A splice_region|QWRTY|ENST00000000003|protein_coding +152 T A splice_region|QWRTY|ENST00000000003|protein_coding + +159 G A splice_donor|QWRTY|ENST00000000003|protein_coding +159 G A splice_donor|QWRTY|ENST00000000003|protein_coding + diff --git a/test/csq.fa b/test/csq.fa new file mode 100644 index 0000000..f534263 --- /dev/null +++ b/test/csq.fa @@ -0,0 +1,34 @@ +>1 +ACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGT +ACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGT +ACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGT +ACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGT +ACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGT +ACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGT +ACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGT +ACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGT +ACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGT +ACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGT +>2 +ACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGT +ACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGT +ACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGT +ACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGT +ACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGT +ACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGT +ACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGT +ACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGT +ACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGT +ACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGT +>3 +ACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGT +ACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGT +ACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGT +ACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGT +ACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGT +ACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGT +ACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGT +ACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGT +ACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGT +ACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGTACGT + diff --git a/test/csq.fa.fai b/test/csq.fa.fai new file mode 100644 index 0000000..12a5aa6 --- /dev/null +++ b/test/csq.fa.fai @@ -0,0 +1,3 @@ +1 600 3 60 61 +2 600 616 60 61 +3 600 1229 60 61 diff --git a/test/csq.gff3 b/test/csq.gff3 new file mode 100644 index 0000000..b00b893 --- /dev/null +++ b/test/csq.gff3 @@ -0,0 +1,40 @@ +##gff-version 3 +#! This file shows which fields are used and required by `bcftools +csq`. It is a trimmed version +#! of the GFF3 format, see an example of the full format here +#! ftp://ftp.ensembl.org/pub/grch37/release-84/gff3/homo_sapiens/ +#! +### +1 . gene 90 200 . + . ID=gene:ENSG00000000001;Name=XYZ;biotype=protein_coding +1 . transcript 90 200 . + . ID=transcript:ENST00000000001;Parent=gene:ENSG00000000001;biotype=protein_coding +1 . exon 90 110 . + . Parent=transcript:ENST00000000001 +1 . five_prime_UTR 90 98 . + . Parent=transcript:ENST00000000001 +1 . CDS 99 110 . + 1 Parent=transcript:ENST00000000001 +1 . exon 120 130 . + . Parent=transcript:ENST00000000001 +1 . CDS 120 130 . + 1 Parent=transcript:ENST00000000001 +1 . exon 140 150 . + . Parent=transcript:ENST00000000001 +1 . CDS 140 150 . + 2 Parent=transcript:ENST00000000001 +1 . exon 160 200 . + . Parent=transcript:ENST00000000001 +1 . CDS 160 171 . + 0 Parent=transcript:ENST00000000001 +1 . three_prime_UTR 172 200 . + . Parent=transcript:ENST00000000001 +2 . gene 80 200 . - . ID=gene:ENSG00000000002;Name=ABC;biotype=protein_coding +2 . transcript 80 200 . - . ID=transcript:ENST00000000002;Parent=gene:ENSG00000000002;biotype=protein_coding +2 . exon 80 110 . - . Parent=transcript:ENST00000000002 +2 . three_prime_UTR 80 98 . - . Parent=transcript:ENST00000000002 +2 . CDS 99 110 . - 0 Parent=transcript:ENST00000000002 +2 . exon 120 130 . - . Parent=transcript:ENST00000000002 +2 . CDS 120 130 . - 2 Parent=transcript:ENST00000000002 +2 . exon 140 150 . - . Parent=transcript:ENST00000000002 +2 . CDS 140 150 . - 1 Parent=transcript:ENST00000000002 +2 . exon 160 200 . - . Parent=transcript:ENST00000000002 +2 . CDS 160 171 . - 1 Parent=transcript:ENST00000000002 +2 . five_prime_UTR 172 200 . - . Parent=transcript:ENST00000000002 +3 . lincRNA_gene 20 50 . - . ID=gene:ENSG00000000004;Name=mir-007;biotype=lincRNA +3 . lincRNA 20 50 . - . ID=transcript:ENSG00000000004;Parent=gene:ENSG00000000004;biotype=lincRNA +3 . gene 100 200 . - . ID=gene:ENSG00000000003;Name=QWRTY;biotype=protein_coding +3 . transcript 100 200 . - . ID=transcript:ENST00000000003;Parent=gene:ENSG00000000003;biotype=protein_coding +3 . exon 100 110 . - . Parent=transcript:ENST00000000003 +3 . three_prime_UTR 100 105 . - . Parent=transcript:ENST00000000003 +3 . CDS 106 110 . - 0 Parent=transcript:ENST00000000003 +3 . exon 160 200 . - . Parent=transcript:ENST00000000003 +3 . CDS 160 171 . - 0 Parent=transcript:ENST00000000003 +3 . five_prime_UTR 172 200 . - . Parent=transcript:ENST00000000003 diff --git a/test/csq.vcf b/test/csq.vcf new file mode 100644 index 0000000..b167938 --- /dev/null +++ b/test/csq.vcf @@ -0,0 +1,40 @@ +##fileformat=VCFv4.2 +##FORMAT= +##INFO= +##contig= +##contig= +##contig= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT SmplAAA SmplBBB +1 90 . C T . . EXP=5_prime_utr|XYZ|ENST00000000001|protein_coding GT 1|0 1|1 +1 102 . C T 1 . EXP=synonymous|XYZ|ENST00000000001|protein_coding|+|1Y|102C>T GT 1|0 1|0 +1 103 . G A 1 . EXP=missense|XYZ|ENST00000000001|protein_coding|+|2V>2I|103G>A GT 1|0 0|0 +1 103 . G C 1 . EXP=missense|XYZ|ENST00000000001|protein_coding|+|2V>2L|103G>C GT 0|0 1|0 +1 107 . G A 1 . EXP=missense|XYZ|ENST00000000001|protein_coding|+|3R>3Q|107G>A+108T>A GT 1|0 1|0 +1 108 . T A 1 . EXP=splice_region|XYZ|ENST00000000001|protein_coding,@107 GT 1|0 1|0 +1 121 . ACG A . . EXP=inframe_deletion|XYZ|ENST00000000001|protein_coding|+|5TY>5I|121ACG>A+124TA>T,splice_region|XYZ|ENST00000000001|protein_coding GT 1|0 1|0 +1 124 . TA T . . EXP=@121 GT 1|0 1|0 +1 128 . T C 1 . EXP=missense|XYZ|ENST00000000001|protein_coding|+|7V>6A|128T>C+129A>C,splice_region|XYZ|ENST00000000001|protein_coding GT 1|0 0/0 +1 129 . A C 1 . EXP=splice_region|XYZ|ENST00000000001|protein_coding,@128 GT 1|0 0/0 +1 140 . TA AACG . . EXP=inframe_insertion|XYZ|ENST00000000001|protein_coding|+|8LR>7QRR|140TA>AACG+142C>CC,splice_region|XYZ|ENST00000000001|protein_coding GT 1|0 0|0 +1 142 . C CC . . EXP=splice_region|XYZ|ENST00000000001|protein_coding,@140 GT 1|0 0|0 +1 145 . AC TA . . EXP=stop_gained|XYZ|ENST00000000001|protein_coding|+|10T>10*|145AC>TA GT 1|0 0|0 +1 160 . TA T . . EXP=*frameshift|XYZ|ENST00000000001|protein_coding|+|12YVRT>12SYV|160TA>T,splice_region|XYZ|ENST00000000001|protein_coding GT 1|0 0|0 +1 190 . C T . . EXP=3_prime_utr|XYZ|ENST00000000001|protein_coding GT 1|0 0|0 +2 97 . A C . . EXP=3_prime_utr|ABC|ENST00000000002|protein_coding GT 1|0 0|0 +2 105 . AC A . . EXP=@121 GT 1|0 0|0 +2 121 . AC A . . EXP=frameshift|ABC|ENST00000000002|protein_coding|-|11VVRTY>11*|105AC>A+121AC>A,splice_region|ABC|ENST00000000002|protein_coding GT 1|0 0|0 +2 126 . C CTT . . EXP=@127 GT 1|0 0|0 +2 127 . G GG . . EXP=inframe_insertion|ABC|ENST00000000002|protein_coding|-|9T>8TK|126C>CTT+127G>GG GT 1|0 0|0 +2 144 . TAC T . . EXP=@148 GT 1|0 0|0 +2 148 . TA T . . EXP=inframe_deletion|ABC|ENST00000000002|protein_coding|-|5YV>5T|144TAC>T+148TA>T,splice_region|ABC|ENST00000000002|protein_coding GT 1|0 0|0 +2 164 . T G . . EXP=missense|ABC|ENST00000000002|protein_coding|-|3T>3P|164T>G GT 1|0 0|0 +2 165 . A C . . EXP=synonymous|ABC|ENST00000000002|protein_coding|-|2R|165A>C GT 1|0 0|0 +2 169 . A G . . EXP=@170 GT 1|0 0|0 +2 170 . C T . . EXP=missense|ABC|ENST00000000002|protein_coding|-|1V>1T|169A>G+170C>T GT 1|0 0|0 +2 199 . G T . . EXP=5_prime_utr|ABC|ENST00000000002|protein_coding GT 1|0 0|0 +3 20 . T A . . EXP=non_coding|mir-007||lincRNA GT 1|0 0|0 +3 109 . ACGTACGT A 1 . EXP=splice_acceptor|QWRTY|ENST00000000003|protein_coding GT 1|0 0|0 +3 113 . A T . . EXP=splice_region|QWRTY|ENST00000000003|protein_coding GT 1|0 0|0 +3 120 . T A . . EXP=intron|QWRTY||protein_coding GT 1|0 0|0 +3 152 . T A . . EXP=splice_region|QWRTY|ENST00000000003|protein_coding GT 1|0 0|0 +3 159 . G A . . EXP=splice_donor|QWRTY|ENST00000000003|protein_coding GT 1|0 0|0 diff --git a/test/csq/ENSG00000173376/ENSG00000173376.fa b/test/csq/ENSG00000173376/ENSG00000173376.fa new file mode 100644 index 0000000..b3269a2 --- /dev/null +++ b/test/csq/ENSG00000173376/ENSG00000173376.fa @@ -0,0 +1,626 @@ +>4 4:121956748-121994196 +ATTGAATACACCAAGGTAGCTGCTTGGGAAAATGAACAGTATATAATCTAATCTCTTTAA +TTTTATGTACATGAATATAATGTATGTCAACTTTGTACATGAGATACATATAGTATTTAA +ACATTTTACTCAACAAACAAGAATTTACAATAGCAATATAACTGACTAGAGGGCTATCAA +CTTAATAATACTTAGATTAGATCTGTACTTTAATAGGAAAAGAATTTAATAGTTTACAAT +CATAGAAACACTGACATTTAAAACAAGAATTTATAAAATAATTTATATATATCCTAGCAT +CTACAGAGAGGAATGATTTGCATTTGTGGGTGTGTGCAATGAATGGCATATTTTAAATTT +TTAGGTAATAAAATAATTTAGAAGCAGTTCATGCAGTGGTCAAAGCAAGGAATGGCAAGT +TCCTTCAAGAAGCCCTCTATCTTTGACACCAACCGGCATCAGACACACACTAGGTACCAT +GGGGCACGCTAGAACAAGTCTCCTTCAAGAGTTACTTATATAAACATCAATATACACACG +TTGATATCCTTCCTTCCATAGTACAAGTACAGGTCACAACTTCTCTCAACTGTGGGAGTA +GTCAGTTTATACTTAAAGTGATTTAATGTCCCTCCTGGAGTTCTACATAATATATCTCTA +TAAGAAGGTAACTAACAGAACTTTCTAGTTTTCACAACCTTACTCTGATACTTTACAGAG +TGCCCCCCATGTCCTATGACATAAACATCCAGCAGGTAAGATTTGCCAGGCTGAAGACCT +TTAATTGTTTCTGTGGTCACTGCTTTCTGCAGGTTTTGACTGTGGAAATATTTACAGAGG +ACCTTTTCTGACTTCTTCCTTATATCTGGTCCTAGACATTGGTTTTGCTCTCTTTTCTTC +TGGTCTTCATTGTAGTTATCATCCACTTCTTTTTTGTAGATGCAAAACTTGTTCCTTTCC +TGAGTGCCTAGCCAAGCCACGGTGGCTGAGGAACAGGTACGGAGCTTGTCAAAGGCTTTG +ATTCTTGTGTCTTCAGGAAGAGAGGGAAATGACTGCTTAGTAGGCCTTGTGGTAGCTAGA +ATTTTCAACATAGATGCTCCTTTCTTGTTTCCTTTCAGTCGAACGAGGTATTTAGCTTTA +GGTTTTCCTCTAAGCTGAAACTGCTGAATGCCTTCCACATTCTGAGACAGAAGAAGTTTC +CCATCTCTTCTCACTTGGATTTGGACAGCATCCAGACAAGAGTGAATAAAGAAGGTGACT +TTTTGGTGAGAAGAGACTGGAGCAAACCGTAGAAACTTTGCTCCCTTCCTTTTAACAAAT +ACATCTGTTATCTTCCCATCTTTTAGCTCGACTGTCTTCTGTTTGGCTTCTTCCTTGGTC +CTGGCAAAGGTACCTACATAAGCGGTGCTCATGTTGCTGTTGATGTTGACCACAAATACA +TCAAAGTAGTACTGCGTGTCGGGTTTCAGATCAGAGACGGTGAAGATGTTCTTGTTTCCT +ATGCAGATTTTCTGAATATCAACCTTGGGCCTGGAGTAGACATGACGCCCCAGTTTTGGA +GAAGGCTTTGCCTGGAAACTGCGTTCTTTACCTGAATTATCAGAAGGAAATCCAAAGTGG +GCAAAGTCAAAGGGGCTGAAGTCCAGACCAGGTTTCGGTGCCATCATAAAAGCATCATCT +GCACTCAGTTTTGCTTCCACTGCACAGAGACTTTTGAAATTGTGCTCTTTGTTGATGACC +ACACAGTACTGAATGGGTTGTTTCAGCAAAGAGGCAGTGGGGCTTGGTTTCCAGGCCAAA +GTGACCGTGGTGCGCCCCAGTGAGGTCACATCTACTCTTGGGTCATAGGGTAACTCAGGG +TATGGCTGATCAGATTCTGGAGTTGTGGTGGCATATACTTTGAAATGTGTGTCTTTCTCT +GTTGAAAGAAGATCCAACTGATATAAACCGGATGGGGAACTAGACGATATAAAATACTCA +ACATCATTGCCTTTGTAGGAGAATAACTCAGTGCCTTCCTCATTAATGATCTGCTGCTTC +TGCTGCTCAAGAGGTTCCAGATCACCTAGAAAATACAGGAGAAGCACAGGCTACTGTCAG +GGCATACACTGTGGCTTGCCAACCTTAAGTTATCCTTTTATCTTATTTTTTCTCCGTTAT +GAAAATAGTACATGTTCATAAGTAAAAATATTTATAAATGTATTCAAGATAATATTTATT +TTGACCATTATACATAATGTTCTTATATATGTGTAAGGCTTCTCTGAATATAAATTATTT +CTTCAGAGCAGAATCCAATTAGTAAAAATTTTAGGTCAGAGACTGTAAACTTTTGAGACA +TTATTAATCCTAACTGTCAATCTGCTTACCAAAAGAATTGTATCAGTTTGCATTTGGATG +GCCAGCCATTTTGCTAATTTCACGGCTGTTAGAAGGACTAGACAATCTGATTAAAATACA +CAATATAAAGTACCAGTAAGAATATTTGGCTGGGTGTCATGGCTCATGCCTGTTATCCTA +GCACTTTGGGATGCTGAGGCTGTAAGATTACTTGAAGCTGAACCTGGACAACAAAGAGAG +ACCCTGTCTCTGTAAGAAATAAAGATAAAAAAATTAGCTGGGCATAGTGGCACATGCTTG +TAGTCCCAGGTACTTGGGAGGCTGAGGCAGGATTGCTTAAGCCCTGGAGTTCAAGGCTGC +AGTGAGCTATGATTGCACCACTGTGCTCTAGCCTGGGCAACAAAGCAAGACCCTGTCTCA +AAATAAGATAAAATAAAATAAAATAAAATAAAATAAAATAAAACAAAACAAAACAAAATA +AAAAAAGAATGCTTAAGGTTCAAAGTATAGAACGTGCACCCAGGAATAACACAGGAATAG +TGGTAAAGCTAAACTAATTTTTTCCATATTTTGTTACCGTAAGTATCAGATATCACACAG +ATATCAGTGTATAGCTTAGTCTCCAGGGCTTGGTGAATGACTGGGTAGCTACAGTGAGAA +GAAACCTTTTCCAGCTTATCATTGCAGGTTGAAAGTGAGCTATACAGAATTTCCTATTCC +TAAACTATGGGATAAACACAATCATCAAACAGATATATTAACATCAAGATTTGGCCAGGT +GCGGTGGCTCACACCAGTAATCACAGCACTTTCGGAGGCCGAGGTGGGCGAATTGCTTGA +GCTCAGGAGTTTGAGACCGGCCTAGGCAAAATAGTGAAACCCTATCTTTACAAAAATACA +AAAAATTAGCTGGGCGTAGTGGCATGCACCTCTGGTCCCAGCTACTTGGGAGGCTGAGGC +AGGAGAATTGCTTAAGCCCAGGAGGTGGAGGTTGCAGTGAGCCAAGATTACACCATTGCA +CTCCTAAGCGACAGAGCAAGACCCTGTCCTGAAAAAAAAAAAAAAAAAGCCCATCAAGAT +TTGTTTTCTGTATCTTGGTCTCTTTACTCCCCATACACACTTCCATAATTTTCCTAATTG +CGATGTTTGCCCCTCTTTGAAACTACTATAGCTAGCCTTTGTAGATACGTATACATAGTT +ATATATATATGTGTATATATATATGTATATATATATATAAAGACTATGTGTGTGTGTGTG +TATATATATATATATATATATATATATATATATATATATATATAAAGACTATGTATATAT +ATATAGTCATTTGTAGGGCACCCATTGTCAAGCCTTCACCTTTAACCTATGATGCCCTTA +AAGAGCTTTCAGGGTGCCATACAAACTCTTCTCATTTCTCTTTTATTTTATTTGCTCTCT +ATCATCTGTCTTCTTTAAATGCTTAGCCCACTCATCCTACTAACTTTGTTTTCATCTTGG +CCTTTAACTGCTACTAAATGCCTCTCTGCTTCTCTGTTTCCATCTGTTATTCCCTGGAGA +TCAGAGGTTCTTAACCTTGGCTGTATATTAGAATCACCTGGGGAGTGTGGCTAAAAATCC +CAAAGTTTGGACCTCACCCCATTCCAATCAAATCAGACCTTTGCAAGATCTAGGCATCAG +CAGTTTTTAAAGCCTTATACGTACGTGATTAGGATGTTTAGGCAAGATTGCAAACCACAG +CCATAGAGGCTAGTCCAAACCTCTCCCCTTCTCCTCAAGCCGTCAATCCCTGTACCTGTC +TCTCCTAACCTTTTATTTTATCAGGATCAGTGTCATCTGATGCCACCCTCCCACTTCCCT +TATCTCCGTCTCATACCTCCAGATTCACTTGTGCACCCATGCTGCCTTTTCTTACTAACA +CATAGAAGGTTGTATGTTTCACAAGCATTAAAACCATCCATTCAAAGGTCCAGGGGCAGA +TCTATCCTGCTGCTTACCTGAGCCTTCCCCGCTCCTGTCCTCTGGCAGCTCCTGGAGGCT +CAGCTTCCACTCCAAAGGCGCATCACAGGGCGTCACTGTGACTGATAATGGAGTATTGTC +TTCTTCAACCACAAAGAAATACCTGTGGGAAAGTGGACCACTTTAGACCGTGGTAATTCT +TTCTAACATTTACAATCAAGACTTACCAGAAAAATCATTTGGTTTTAATTTTTTTTTCAT +TTTATAAATTTTATAAAATTTTCATAAAATGTCATTGTATTTTCCCTTAACACAGTTTAA +TAAAATTGGCTATTTGACACAAAACATGATACAGCATTAACTGTGGAAGTCCAACAGCCC +CAAGGATCTGCAACCAGATTTATCATCAACAAATACAGCGTGAAATAAAACACATTGAAC +CCAAAGTATTTTGAGTTAAAAATCAACACTGACCTGTTGCCTGGTATTATTTAACACAGG +CCCCGCCACTGCAAAATAAATCACAACCAAGAAAATTTCCAGGTTTGTTGCCCTATAGGT +GCCATGCTTTCCATACATTTGGTGATAAATTTGTACATTAACTTGAGGGCACTCTGACAT +AGTTGCAACTATTTCAAAAGAACATTTTCACAGCAACCTAGTTCTAAACTGTGTGTTTGT +CTCTGGCAATATAACGCTGTATTCACATTTTTACATTAGTGACTTTTATTCACAGCTTTA +CTATTTCATATCTTTTTATTTGTTTGTTTTGAGACAGTCTTGTGCTGTCTCCCAGGCAGG +AGTGCAGTGGCGTGGTCATAGCTCCCTGCAGCCTCAAACTCCTGGGCTCAAACGATCCTC +CCACCTCAGTTTCCTGAGTAGCTGGGACTGCAGGCGTGTGCCACCATATCTGGCTAATTT +TTAAATTTTTTTGTACAGATGGGGGTCTCACTGTGGTGCTCTGACTGGTCTCAAATTCTT +GGCCTCCAGTGATCCTCCTGCCTCAGCCTTCCAAAGCACTGGGATTACAAGTGTGAGGCA +CCATGCCTAGCCCATTTCATATCTTTTGGAATCGCATTATCTAATCACCATTTGAGAAAT +ACTTTAAAAAGTAAAGAGCACTGTGTCAGTCAGTAGAAAGACACATTTCTCTAACACAGG +TTTTCTGTTGAATTAAATAACTTAATGATTTTAAAACAAAATTTAAAAAATCAAATGTTC +TACTCTGTGCTTTCCCCTGAGCCTTTATTGTAATGCCTTAAAAAGAATAAAAATATTGCT +TAACTATAGAAATACCATATACTCTTACTCCAAATGACTTAGATGGTTTCATTTAATTAT +CTTTCAAAACCTATAATCTTGCCAATGAGGAAAGAGTGGTTTCAGTTCCAGCAAGCCCAG +AGTTGCTCATTGATTCCATGCAGAGAAAAGCAGGCTTTGCCTCCTGTGGATTGAACCTCC +TGGATATCTCTTGCCTTCCTATTCTCTCCATAACCCTGACCAACACTGACCACCAGAGCC +TCCGACCCCAGCAGTCTCTTCTGCTGGTTCCTTCTCACCTCCCTGAACTCTAATGTTGGG +AGTGAACCACAGGACTGTGCTTGAACGTCTCTTTTCTACCTATGCTCACTCCCTGTGTGA +CCTCATCCAGGCTCATACAATTAAGGAATTTTTCCCTAAGGCTAAAACCTAAAGCTCCGA +TAGGACTCTCAGCTGGAAATCACATAGTACATTTGCTTTTTTAGGAGATTCCTCTTGCTG +CAGTTTTAAGGAATGATTCGGAGGTGGTGAAAGTGGAGGTATGGGAAACTACTCATTAAT +TCATCCAACAAACATTCCTTGAGATTTATTTTAGTCTTTGAGACTAAAGAAAAAGCATCC +CCGAAGAAATGACTTTACATGTGAGTTGGGGCAAAGGAGTTCTTTTCAGGCAGAGAAAAC +CACATCCCATAGACGGTAGGGTGAGTAGGGTTCAGAAACTAGAGAAGTACTTTGTGGTTT +GAGCACAGAGTTAAGTGGGTAGTGACAGGACAAGAAACAGGTGAGGTAGGCAGAGGCCCT +GTCACTACAGAGGTTTGTGACTCATACTCACATTTAGAGTCATTTCTTCAGGGATGCTTT +TTCCAACTCACTCTGGATCAGGTCCTCTGATGCATTCTCAGAACGTCCTATACTTTTTAC +TTTCGGGCACTTATTGTTACTTGTGACTATATAATTGTATTATCATTTGATTAATGTCAT +TTTCCTCACAAGGGCCCTGTTAGGGTTCATTTATCACGCCTTTGTATTCCCAGCAATTAG +CACAGGTTTCTGCATGTATGTACTTGATCAACATTTTAAAATAATTGAATTACTAAATAA +GTAAATAAAACCTAAGAATCCTAACACCACACTTCTTGTTCTAGCCTGGTTCATACACCT +AGAGTCTCCTTCTATCTGAAGATATAGAATCTGAATTGAAATACAAGTACTTCCCCCAGC +CACCACCATTCAAAGATGCTTTTGGAGATGGAGAATGGGAGTGGGGCTGTGGGCAGACAA +ATAAAGTGAAGACCCTATAAATGCAAAAGCAACTTATTCATATAACAGTAAAGTTAAACA +ATCATCTAGACAAAATAGATGATTGAATTGTTTACTGTATGTGAAGTTTAATGTACCATA +AGCATTCCTGAACAGTGTCAGAAGGCTTAATTTTTAATACAGTCTACTTTTTGTGAGTAG +AATTTTGTCCCTTTGGCCAGATTGCATGGGAGTTATTAACCACATAAACATAATTGAACC +TATCTATATTACAAAGGAATAGGTACAACAATATAACTAGTTTGGCATCATATAAGTAAA +AGAGTGTTCAAAACTTCGTGTTTGATTTTAGGTTTTATGTGAATAACAGAGCTAAGCAAC +GGCACAGAAGAAAACAATGTACAAGTTTGTCTATTACCTTCTGTTCTCATTTCACACAAG +GAAGTAGTTTATTTCCAAAACTGTGTCTTAGTAACTTAAACGTAGGTCATAGGTGACCAG +TTACAAATAAAACAATGCTTTCATTCCACAAGATAATGATTATGCATATAAAGCAGCAGG +GAGACCCTCTAAGTTAACATTTTCATATGGAAGCACTTATGATTAGGGATAAATGATAAT +TTGAATATACTTAACAATTTGACAGATATTTATTGTCTACCATGCACAAAGCAACTGTAG +AAGAGAGTGACAATCAGAGATGACGGGACATAATCTACATGTTCGAGATATTTACTGGCT +AGTGAGGGACACAGAAACATAATTAATAACTAAGGAAACATGGCCCAAATTATAGTGCCA +AAGCTGAGGGATAAGCACACCATGAGCCATTTAGCCTTTGGAATTTATGTATAAACGTAA +GAATAATTAATGCATTTGCTGTCTTTTTAAATTTACTGCTGTGCAACTTTATCTGGAATT +TCTTTTTTTAGTTGGAATATCAACAACATGTTTGTGTGCTTATCATTACATATTTCACCC +CTAGAAATGAAGTTTCTACTTGTGGTTATAATCCTTTACTAGCATAAGTCTGCTTTTACT +AGTGTATGTTAACATTTTTTCCTATTGTGGATACCAAGGGCCTCAATAATCATTGGCGGA +AAAAAGATAAATATAAAGAATGAATAAATGAGAGAAATAAAAAGAGAAAATGTTGTTTTA +TAATGTCTCTTAATAAAAACATGGCGCTTTACTTTAAAAGTGTAATTTCTAAAACAGCTC +TTACAGGCAAAACTTATTTAATTTTTAAGAAACTGGAAGACTAAAGAAAGATGAATCATT +TAATTAAGTGATTGGATTACATAATGTGGAATGCTGTATTTAAAGTATATTGCAAAGAAG +GCAGTGCCCAAGTGCATTTGGGAAATGAAAGTAATTTCTACAGAAAAATTTTGATTTGAT +TTCACTCACACGTAAATTTCAAAGGACAAAATAATATGAAAAGCCAAATGTGCCCAGCAA +GAACTCAGTTAATAGTTAAGATTAACTTGAAGTATTATGACTGCTTTGTATGCCTTTTAC +TGTTTTCACAGACTCAATTTTAGTCAGGACCAAGAGAGCAAGTTCCTTCAATGTAATCAT +CCTTTCCTTTTCTGCCTTCACTCCCATGAATGTCATTTAAAGATTCAAAATTATTTTATA +TGTTATTGACAAGTCAGTTACTAGTCTAGTGTGTTCATGCAAACAAATAATTTTACTCGA +GCAGTGCCAAAATGATAATCCGAACAATAGTTCACTCTAGTTAATGTAGGAAAACTGATC +ACCTATCATCATTTTGACTAACCAGATGGAGATAAGACTGGGCCATTGAGTGGAAGGGGT +TCAGACCACCATCTTCCATGATTACTGTTAATCAAAACTGAAAAGATGACTAATGATCTG +ATATATCTCAATCTCTAGAAAATGGGTTATTGATGTTCTGAAACAGTTTAATCCTTTGGA +ATTTCACTGTATCCCAGGTTAGAAGGAGCAACTGGTTTTGAAATATAATTATCCAAAGAT +TAACTGTGTGTGCTAAACTTACAAAGGGAGAAGAGTTTGAGCACTACAAAATAGGTAACT +TTAAATGTAATTAATTTATAACATATTATTTTTATTTTATATATATATATATTTTAAAGG +TCAAAATATTTAGAAACTTTATGTGAGCCCAATTTGTTGATGTTGGAGTAAAGGTAAATA +AACCGTGTCAGTTTTTATGACTGTTTAGTTTGATTCTCTCAGAATATGATAATATTTGTT +GAAGAAATATTATACTCATAAAACATAATGCATTAAGTGTGGTGTCTCATGCCTGTAATC +CCAACACTTTGGGATGCTGAGGCAGGAGGATCACTTGAGCTCAGGAGTTAGAGACCAGCC +TGGGCAACATAGTGAGACACCATCTCTACTACAAATTTTAAAAATTTGAGGGGAAAGGTG +GCACACACCTATAGTCCCAGCTATTCATGAGGCTGAGGTGGGAGGATTGATTCATCCCGG +GATGTTGAGGCTACAATGAGCCATGACCGTGCTACTGCACTCCAACCTGAGCAACACAGT +GAGACCTTGTCTCAGAAACAAAACTTAATGCAAACTCTTGAAGAATCATACATATTCATG +AAAATTGATTTCACTTTAATCCTACAGAATCCTTCTTAGAAATATCCTACTGTACTGAGG +CCGGGCGCAGTGGCTTACGCCTGTAATCCCAGCATTTTGGGCGGCCAAAGAGGGCGGATC +ACGAGGTCAGGAGATCGAGACTATCCCGGCTAACATGGTGAAACCCCGTCTCTATTAAAA +ATACAAAAAATTAGCCAGGCGTGGTGGAGGACGCCTGTAGTCCCAGCTACTCGGGAGGCT +GAGGCAGGAGAATGGCGTGAACCCAGGAGGCGGAGCTTGCAGTCAGCCGAGATTGTGCCA +CTGCACTCCAGCCTGGGCAACAGAGCGAGACTCCGTCTCAGGGAAAAAAAAAAAAAAATC +CTCCTGTACTGAAAAGAAGAAAATAATCATTCCAAAATGTAAGAAATGCAAGCATTGCCT +CCTACACGCAAAAGGAGATGACAATCAGCAAGAATCAAACAGCCTCTATTTCATAATTAG +AAGTTGCACTGCCATGTTCCCCCTTACTTACAGAAAATCGGTAATGCCATTCATAGGTTG +ATTTGTAAATTACCTAAACTAAGTCTAAAGGTTACTCTCTTTTTTGGAGGCATCCTTTGT +GAGCTTTTTAATAAAGAAAATACTGCAGGGAGAATACCTCTTAGGTGTATCTCTAAAGAG +ATAACTGCTAATTTCAGCTCCATCTGGAATTACTGACGAATCATGAAAAAATGCCTTGTC +CCGGATCTGCATCTGAAAAAGTTCCTCATCCCGGGTGGGTAACTTCTGGGTCCTTGAGCT +GAGTGGAAACAGGAGCCACAGCAGGCACCAGTGGAGCAGCACCATCCTGAGGCAACAGAA +ATGACTACTTTATTAGTTCTGCAGGCAGACACTCAGGCAAGTCACAGACTTTCTAAAGGG +TTAACACTATTTTAGCTTTGATGGAAATTTAGGGACGCATCATGTATTTTGGATACATAC +ACATGATCTTCAAGGCAACTTTACTATATTTTTTCTTCAAACATTTTCATGATGTTAAAA +ATAAATTCACTAGAATTTCAGACATTAAAAAGATTTTGAAATGAAAAGACTCTTGCTGCA +TTAACTTCTCTGGGTATTCAGAGAGAAAATCCTCACTTCATTACAGCAGAAGCCTATATG +GACATTGTAGATAACGCTATATCAATGTCTCAAAGCTTGCACGAAAATAATCTCTTAAGG +TCAGTTTTTTGAACTATTATAAAAGTTATACCAATGGTTGGTTGGTATCATTGCTCAGCA +GTCAAGTTGCTAATTGCTGATATGGTTGAACTATTACATTCAACATAAATCACAGAGACT +CATTGAGAACCAGAAAATTATCACTGCTCAATTATTTTTATTCTTCCCTAAAATCTGACT +AGGGGTTATACATATATAACTCTCTACGTAGTATTATGCTTTTTCCAAGATCAAATTTTC +ATAAGTCAAGGATTTTTATAAATCATAAACTTCATCTCCTTCACAGATTAAGCAATTTGT +CCAGAATCACAAGATGAGTTATTAGTTGATGTTTAGTTGTTATCAGGTACCAGAGTCTTC +AACACAACGTTGACATATACACCTCTATCATTTTAGAAAATGGGCTTGAACCTTCACTCA +CACATCAAGCCAGAAAGGTGTATATTTAGAACATTTGTCTTAACCTCCAGCAGAGAGTAC +TTTCACTGAGTTACATTTTGGCATTTGTCACTGACTTTCATCAAAGATCCTCTAAGTAAT +GATGGATCATTCTCTACTGCACATTGCTGTAGGGGTGTTGTCAAAGACACTGTCTTCCAC +ATGTCTTGGTGTTCCCAACAGGAAGCCCCAGGTAGGCAAGTTCCTTGACATGACAGGTCT +CATGAAAAAACTTTGCTTCCTCTGACCATTTGGTATTTTTTTTTCCTCACAGAAAGAAAT +ATGTAAAGAATTGTTTTCCTTTACCTCTTTGACTTAACATACATCAGGGAATTAAAGCAT +TAGAGAAATATAGTGTTTTTACATTGAGGTACTTTAAATAGCAAATATTTGTGATAATTC +AAGATGAAGTGAATGCCAGTTTTATTTTTAAATGGACATTACTATAATCAACCTCTACTT +AAAACATCATTTGATTTTAATTTTATCTTTCTTTGAATGCTATCAAAAATAGATTCAGAT +TGCAAAAATATATAGTTTGAAAGAAATAACATTCTCTTTTTTACAATGTGGACATGAGAG +TTGGATTTTTCACAACGAGCTTGTGCAAAATGCATTTTACTTTTCTCCAAATATTCTTTG +CTGTTCTGTGTTCTGCGGTTTTCCATACAAAATATCTGCAGTGATCTAGAGCTACTATGT +GCAAAGCACTGTTCTAAGTTCACGAGTTGCATTACTACTTTTAGTCCTCACAATAAGCCT +GTGAAGTAGCTGCTATCCTATGCAAAAACAAAACTCCATTAGGTAAGCAGAGAAAGGATA +CAAATACAGGTGGATCTGACTGCAGAGCCCAGTGTTCATCCTCTGTAATATCTCTCCAGA +AAGCCATAATAACTTATTATGAGGCTTTTCTTTCCCACTCTTATTTCTTAATTGTATTGC +AAGTGTAAGAAAATTCAACTGAGAGCTAAGAAACTTGATGTTTAGCTTCAGTTCCTTACT +AGATGTGTGATCTTAGGCAATTCACCTAGCCACTCCGGACCTCAGTTTTTTGAAGAGTTT +GGATGGGTGATCTATAATCAGCAATGCTTCTGAGACTGAATAAACTTTTCTTCCTAAAAA +GCTGGCAGTTTAAGAATAAGACCAGGCCTTCTTAAGTTGCCTGAAGTAATCTCTCCCTCA +GATATCCAGATGATTGTCAAGGAGAAATCCAAAAGAACTTGGGGATGTCAGTGGGAGCTC +ATGAGAGTTGCTAACAGTAGACAAGGGCTATGTCTGCAAAAGATGGCTGGATGGATCAAA +ATCAAGACTAGGTTGATATAATCTAACCAAGCAAGGACATGGTGGACTGACCTGAATGGG +ACCTCCCTCACTGCTGTCTGTCCCTCCCCTCTGCTCCTCTTTTGTTTGGAGCTAACAGAA +ACTGAAAATCCAAATGGCATTTGCTATGCTGCCTCTGTTTAGAAATACCATAGACATGCC +ACATGCAATTCTACAAGTTTATTTCTCTTTGTAGTACCATCCCCAAAACTTGCCTTGTGA +GAACAGACGAGGCCAAATAAAGAAGAAAATCTCTTTAGAAATAGCTAGAATTTCGCTTTC +TGTACTTGTTAGAAATTTAGCAAACATGCTATCAGAGCACTTGAAAGCGAGATACACAGG +CATATTTGCCTCAGAGCCACTCAAGGCTTACCTCCTTAGGCCCCATGTTTGCCCACAAAG +CTGCCAACCACGGTGCCACAGTATGACTTAGCAGGACAAGCTGCCTAAGGACCCAGGGTA +TCTGGGATATTTAGGTCAGCCCGAGTTGGAAAAATAGTGTCGATTGATAGGAACTTTCCC +TGCATCCTCAACTGCCCTAGGAAAGAACTCTCTATTAAATCAGATACTTATAAAAAATGA +ATTCTGGCTGGGCGCAGTGGCTCACGCCCGTAATCCCAGCACTTTGGGAGGCCAAGGCAG +GTGGATCACGAGGTCAGGAGTTTGAGACCAGCCTGGCCAACATGGCAAAACCCCGTCTCT +ACTAAAAATACAAAAATTAGCTGCGTGTGGTGGTGGGCGCCTGTAATCCCAGCTACTTGG +GAGGCTGATGCAGGAGAATCGCTTGAACCCAGGCAGCGGAGGTTGTAGTGAGCCAAGATC +ACGCCACTGCACTCCAGCATGGGCGACAGAGCCTCCGTCTCAAAAAAAGAAAAAAAAATC +TGAGATAAAAACAATATTAATAAATTTTGTTGTATACATGCCACATGCCAGGCATTCTTC +TAAGTTCTTTATATATATTATTTCATCTAATGCTAGCAACAACACTATAATGTAGGCACT +ATTCTTTTTTCTCATTTTAAAAATGATCAAAGTGAGACTTAGATAAGTAAGGTCATACAG +TAAATACTATCTGATGTAAAAAATATGAACTATTTATTATAGGTGGCTTAAAATATGGTA +AATCTGATTATTATATATTCTCCAGTTCAGCTACTTAACAAATTAATATTAGTAAACAAA +TTCAAGTTATAGGATTATGCAGAGTAAGTGTTGGGAGGCAATTCTCCATGGGTCTCTGTG +TTTGCTTTTGCAAGTACTTGGGAGCAGAAGTACTGACTGCTTTTGTTCCACATTATCTTT +TCAAGGATATTTGTATAGTGAGCAGTCTTGGCAGATAAAGCCTCTGGAGCAAAGAGCAGG +CATGGCTACCACCGATTATAGAAGATTTTAGGTCCCTAAATTCAGGGATCCTCTCTTGTA +ATAAAATCCAAACATGGCCCAGTGCCCGCTGGCCCTCTTTGCATCATCCTGTGGGAAGTG +GGGGTCAGGGAGCCAGTGGAAGAAAATAATGATACTCTGCCTGAGTAATACGTCACTCTG +AGTAATAAAGTCCTTTGTCTCTGACCCAGGAGTATCTTGCCTTCTTCTAGCATCCATGAA +ACTATGACAGACTAATTTATTAGCTTGCAAGTGGGCTAAAATCTCAAGTCTTTCATAGTC +TTTGACACTAAGCTTCTATTTATTAAACTATTTTACTGGTTTACCTACTTTATTGGCTCA +GGTAGATATTTTTATTTAGACAATCACCAATAGATAATGGACTGAAACTTTATCTTTTGC +TTTATCAAAAACATCATATTTCCCAAACTAAAATTCCATCAGGCCACATTTTTTGTTTCT +GAAACAGTTTTAACCATCTCAATTGCTATGCCAATTATGGGCAAAACATACTTTTCAAAA +AAGTTTTAAAAATTTGTATGGACCCCAAACACAGGAATTTATACTCTGTCAGATTCTGGT +TCTACAAATATTATCTAATAACATGCAACTACTGTTGGGGAAAAACTTAAATATTAGGGA +GCACTGATGGCTTGTTCAATTTGGTCAGGTTACAGGCAGAAGTTAAAATGTATTTACAAG +GAGCATTGAATATAGCTAATCAAAAAATGACTGTGTAGATACATTGTATATATTTTTACA +ACTTATATTGACTGATAAAAAATTGAAGCTTTACATAAATATTATTTAAATGGTGGTTTT +AAGATTTTACACATTTTTCCCTAACAATAAAATGTTCTGTCTCAGATATACAATTTAAGA +ATTAGTCATTGAGAATAAACAAATGAAAATTCATTCTTGTTAAGCATAAGCCTTAAATTG +CTTTATAAGAACAGACTTTTTTTCTAAGATTACAAAAGTGCCCTCTAATGGCATAACTTT +TCCTCTCATTTCTTTTTGTTACTTCTAGGTAGGCAGAGCTTATCTAGATTTAAACTTTAC +ATTAAATAACATCAATCAGAGTTTCACTTTAAGCACTTTCTTTTTTCATGGCCATCTGGT +GGATGATGTAGGAAATGTGTTTGCACAGCAACAAATCTTGCTATCTTTCTACAATTGAGG +CTTTAGTTCAAACATAAGCTGAAAGTTGCTAGGATAATTCCAAATATTTTTATTTTGCTT +GGCAGATCAACTTGGTTGCACAGTATCCACAACCCAAAAGAACTTGGTAGTGTTACTCTG +ATACTGAAAAAATTGACTTTGTTTCAATTGAAAAGTTCTAATGAATAAAAGATATAGATG +CAATCTATAATTCTGCTATTTTTGTGTTGTCAAAGGCCTTCTTCACATTTGGCACAAGTC +CTCAGATCCTGCTAAAACTGAGGTGAGAAAATAAAAATGACCTAATGATTTGATACAACT +CAATCTTTAGAAAATAGATTATTGGTGATATGAGATTTTTCTTTGGAATGCCAATATCCT +ACAGGGGAAATAAAATTGTCCAAAGGTTAACCATATAGTCTATACTTACAAAGGTAGAGA +TGGGTTTGGATAATCCAAAGTAAATAACTAGTTTATATGGTGTATGAATATATACACACA +CATATTTTTAGATCAAAAATGTGGAAACATTATGAGTTCAATCAGCTGATATTGGAGTTA +AGGCAAATAAGTAGTAGTCCCCAAAGAGGAAACTTTTAAATATAAAAATGGAACATCTGC +TGCCCACTTTCTTGCGAGCAGGTAAATACTATACAACCCAAGAGATATGGAGAAGGGATT +CTTTCTAATGTTTTAGGACTATGGTGATGGGAACTTGCTTCTCCCCTTCATTTCCTCCAG +TTTTAAAGAAAATGTCAGTGAATAGATTTAAAGCGTTTTTATTGTTCTGCAAGGAGTAGG +GAGTGGAGCACATGATGGATAATTGAACATGTACAGACAATTCTAAGCCTTTCTTTAGCA +TTAATTTAAACTTCATATTCTATGGAACTTTTAGATAAAATAAACTGTCCAACTGACCTG +GCATATCTTTTTCCCACAAACCTGTGGAAATGCTTGTAAATTATAAAATGGTCAATGGTA +AGCAAAGTAAAAATTTAAAGGGAGTTTGAGTAATTCATTGTATCAATTAAATACCCAGAA +TTACCTCTATCATCACAAAAAAGCACAACATACCCTACAAAAATTCAACTTGCCCCAGAA +TGTCTATAGCAGTTCTACTGCTGTCATTTTGCAAAATTTATCTGCAATTACATAAGATCA +ACTAGTCAATTTACCCATCTGGGTTAAACCACTGGTTCAGTTAGTTAACATTTATTCTTT +GAAATTGTATGAACAGTGATAAGAAATAAATCTGGCTAATTTTTTTTCCTTAAAAATCCA +CTAAATGGTTTTACCACATAAAACAATTAAGACTTTTAAGAGCAGACTCTTATTTCAACC +ACTAGAAAGCTTGTCTTTAATAGTTATAGACTGCTATTTGGCTATATTATCTGAGCAATT +CAAACAATTGCAAATCTGGTAGATAGAAAGTTCTTTTGGGCTTTCATGTAAAGGTCCAAG +GCTCTCAAAATAGAAGACGTGATATAAATTAATGCACTGTGACCTTTCTCATCACTGTAG +CTTCCTCAGAACAGCAGCCAACAGCTTTACCTACCTGTGATAATATGATCAAAACAAATT +CCTCCATCCCTCTATCACCAACAAGTTCTTTGCAGAAATGTATAAATGTAGTTGTGAAAA +ATGTCATCAAGCTCTTACACACTTTACATATTATAAAATTTAAGATCAGATTCATCACTA +TAAATATAACATAAAGTATAAAATTTGAAAAAATATATAGTATCACTGAGATTCGCTTAA +AAATTATCTAATGTGCCTGATCATGTGCAGGCCACGAAGTTGAAATACATTTACAATGAC +AAAAAAGGATGGGCATTCTGATTTACTTGAAGCAAATGTATAGAGAATAAATGAAATCTA +ATGTTTAATTAAAGAGAGTGGAAAGTGCATGATTATAATTTGGCGAGAATAATTTCAAGG +AATGGTCTGCCACAGAGATTTCTGTTATTTTCTTTTCCTTTCTAAATGCAAATATTTAGT +CTTTTAAATTTCTATTTTCAAACTCAAGAGCATTTGTTTTTGTTTGAATCATCCATGTCA +CATTTGATAATAAATCTGAAGCATTTGGTCCAGGTGTAAGAAAAAAATATATAGCTTTAG +TTAGGGGAAGAGCCGTGTGTCTGCCATGACTTGCTGGGCAGCAAGCGAAGAGGACTGCAC +ACTTTAATACTGAATGTCCAACATGTGCCAGCGTGGATGTACGGATTCCTTCGAGGCAAA +AATGCAGCAATCAAAAGTTGAATTCCCAAAAGGTGTTTTATTTTGTTTTCTTTTGCAAAC +AATGAAAATGTCTGAAGTTAGTTGTTCTTAAAAATCCAAATCTGTTAAAAATTTGAAGGA +AATACAGCATATTATGGGCTGACATTTCCATACCTGAAAAGGGAGAAATAAAGCAGATGG +AAGTAAAGGATTCCTGGTCTGCCCTGACGAGTGGTCTCTGGCACATGCTAGGTGAGCTCT +CACTCTGCGATAACATGCCAACTTCTACCCAACCCAATGAAGTAGAGCCGACATTATGTA +CAGAACTCGTGCACTAAAGCTCTCTAAATGCAGGCTGTCAGTACACAGTGACATGATTAT +TAAGAGTTTTAGAGTTCATTATGTCAATAATCTACAGATTAGGGACCTGCACATGCATTT +CAACTGCAATGATTCCAACCTCCCTTAGCACTTCTCTAAATGACTGCCAACTTTCCTTCT +GGAAGGAAATTAAATTAATATAAAAAAGCAATGTGAAATTAAAACATGCCAAGGATTCGA +ATAAAGTTTCCATTCTGTCATGCGCTCCCTCTGAGTCTCATGATGCAGAGTTCCTAACAG +GGATAACGTTAGGGCATTCTAATTTAAAAGATGGCCAAGCCTACACAATCAGAATTACTT +CAAAGAGGATCAGATTTTAAAGTAAGTAATCTTGTATTCCCATCAATATTAATGCCAATG +AGAAGAATAATGAATAACAGAACTGGCCGAAATAAATGTCTCATAGATAGGAGTAGTCTG +TAATTCAGGAAGCCAGACCCATTTTAGTAAAGAAAGGAGTAGAACTCTTAAAATGTATCA +GATGGATGGTTAGAAGATATGACAAAGTTCAAAAGCAGTGTATGGGAGAATGCAAAGAAA +AACTGGAACAGAATACTAAATACCTTCTTCCTATCAAAATGTCCTCTATATGTGAAACTG +AGATAGCTGGGATAACTTCCACTGTCTTAGGTGATGCTAATGATTCTTAGAATAATGAAA +GCCCCAAAGGAAGGAATAATATGCTTGGTTGCTTTTCTTGCTTTTGTTTGGCAACTAAGC +CTTATTTCCTGTTGATCTGCAACCAAATGAAAATGACTTCCTGTGCAACATTCCCCAAAG +CAGTTTACAAACTGCATACCTCATTCTCTACTGAAATTTAGCTAAGATGGAGCATGGCAG +CGCGCCAGTAGCATTCAGCAACAGCACGTATCAGCCTGGAAGGTGAGGCATGAATTGTTG +TGGTCAATAAAAAAATATTGAGTCACTGCAGTGTGTAGCACCATAAAAATTTGATTTTTT +ATAGCCATTTATCCAAGAAGTTAACTCTTCAGTAAGTCACTCCATGGATTTCTTAGGATA +CCAAAACCTAAATATGGCCAAAAGAGCAAAAAATGAAGAGAATAAGAGTTTTGTCAAATA +TCGATGTCATACTCCAAACTCAACTGGGTAATGTGAGGTCTGAAAAAATATGTATCTTAG +GAACTTAGAATCTATTTATGGGGCAAAATGTACCTGCCCAGCCAACAGAGTCCAATGTCA +GCATTTCTACTCATTCATTATTTTTTTAATTCAATATCTATATAATACATTTTTGCTACA +TGCCAGGTACTCTTCTAGGAACAGTGGTGACCTCAGGAAGTGAGTGTTCTAGTGGGAGTG +ACAGGCAACACATAAACAGATACACAAGAAAATACTATTGCTGCTAGCTATGCTAAAAAT +TAAAATAGGCTTCTGTGAAAGACAGTGTGGTGATGGGCATTTTAGATTGAGTATTTAGAG +AAGTTTTCCTTGAGGAGATGACATTTATGCTGTCATCTGAATGACAAGAGGAAGCCAATG +AAGCAAATAAATGTCAGGAGAAAAAGCATTCTGGGCAGAGAAATAGCTGGTGCAAAGGCA +CCAAGGTTGCACTAAGCTTGAGGTATTGACAAAAGGAAAGGACATCACTGTGGAACACAG +TGGGTGAGGGAAGAATGGAAGACCAAGTGCCAATCACATAGAGATTCACATCCATATTAA +GGGGTTTGGATTCTGTTCTAAGCGTGTTGGGAAGGCCCCCATTGCCAACTTTTTTGAGAC +AGGGTCTTGCTCTGTTGCCAAGGCTGGAGTGCAGTGGTGCAATCATGGCTCACTGCAACC +TCTACCTCCTGAGCTCAACAGATCCTTCCGCCTCAGCCTTCTGAGTAGCTGGGACTACAG +GTGTGTGCCACCTTACTCAGCTAGGTTTTTTTTTTTATTTTTGTATAGAAGGGATCTTGC +CACGTTGCCCAGGTTGGTCTCAAACCCCTGGGCTCGGGTGATCCTTCCGTCTTGGCCTCC +CAAAGTGCTGGGATTACAGGCATGAGTGGAAAGCTCTTTAAGCACAGAAAGGCCATGAAG +TGATCCAAGCTTTTTTAGGAATAACCCTGTCTATTGTGCAGAAAATGGATTTCAGTGAAG +TGGTAGTTTTAAAAGCAGAAAACAACTTCATCTTTCTGAAACAAAAAGATCAGATGAAGG +CTACTGCAGTTGTCCATGGTAGAGATGGTGGTTTTTTCAGCTTTGTAGAGGAGATGAGGA +ATAATGGAAAAACTGGGGATATGCTTTGCAGTTGGATTGCCAGAATGTGCTGGTAAGTTG +GAGGAAGGAAGTGAGGAAAAAAGAGGAATAAAAAATAACACATTGATTATAGGAACGTGC +ATATGATAAAATGACAAACAGAAAGTACTGCAAAGGTGGAAGAAATGAGAGAAATAAATT +AGTTAAGCAGAATTTTCAGGTGGCATCAAATAGCCTGAATAGCTGTCTATCTTAGATGCA +GTTTTAAAAACTGGTTATTATATTTAAGAAGGTATTAGAAGAAAGGAGAAAAAGAGGAAG +GCATTCTCTTTAAATGATGAGAAACATAAATGAGGAGAGGCTACAGTGGAAATTAGTAGG +AAGTGTGGCTAAAAAAATAAAAAGACTGATTTCAATTATCATGGTGGGAAATGGGATCCG +CCAGATACATGGATGGTTGAAGAGACATATTAGAGAAAGGCAATACATACACACATACAC +ACACACACACGCACCCCAGAAGTTGCTTCTTTGAACTTAAATTTTAAGTGAAGGGATGCA +TATTATTTGAGGCCAACCCATTTGTTGAAAGTACCCAGAGAAGAAAGAAGTCCAAAGGCA +TATTTTCGTCCTGGAAAGTGGTTGTTATGGTAAATGAGCAGGAAACAGAATTAAGAAAGA +CAGATACAGAAGGTATGAAGAAAATCTGACAAGAAAATATTACTATTTGGTATATGTGAC +CAGACCTCTTCATAAACTGTATCCAAACAGATAGGCTAAATAAAACCTGTGAGCCTTCCT +ACAAACTCACACCTGCCAAATACCATATAACTTATGCTACTGGGCACTTATTTGGAAAGA +AGCACCATCCCTGGAGGAATTCTAAAGGCAATGGAATAATCCGGAATGTAGCGAACTACA +CAGGCACCAGCAGGGAAGTGGCAGATGGTGAGCTCAGTGAAGAAAAGACCAGGAGGGAAT +TGACTGCAGTCACTGAGACAGTTGAGAAAACCAGGCTAGAGAGAGTAAGGAAGTGACTGG +CAGCGTCTTTAGGATGGACACCAAGCTTTGATGTATAATACTCTACAGGGCAGGTCAGCA +ATCTTTTCATACATTTTGCAATACACATGTTAAATGCTCACTAAATACTGATGGATCAAA +TCGAACCATCACTATCTCTTCTGAATTGAGATAACTACTGGTTTTGTTTGCTAGTAACAG +CAAGGATAAAACTGAAAGACTAAAACAGAATACTACAGCAAGAAAAAAAGATTCTAAAAA +ACTATCAATCATTTCATTCAGGCACGACCTTGAATTTCTGCATATTTTCCATCTATCTCA +GGCCATATGTACTATCTTCTTAAAGGATCTTCAACATTCAAAAGGTGTTTCTAGTTCTAC +TTACCATATTAACAAGACAAGGTACTTAACATGATTCAAGTTCAAAGATGTTTCTGTTCT +TATAACAAACCTGGTTTTAAAAACTGCCTTGGTGATTCTACTGGCAATGTCTGTTAAACA +CATGGGTTGCATCCTCCCTAAAGTTTCCATCAAAGAAATCTTTTATAACCCAGCTTCCAG +TGATGTAGTAAGCGATACCCACCAATAAGGCAGTGACAACAGAAAAGAGCAAGTGTGGTG +GGATTATGGAGTGGGTAATTCCACAAATACAAGTAGGGCATTTACTGTGTACTAGGCACT +GCCTGACGTGCTGCGAATGAGGCAGCGAACAAGATGTGTGAAGATCTTGAGCTCGTAGAG +CTTATACTCAGTGGATAAGAGGGATGAAAAACAAGTAAAGAACAAAGTATAATTAATATA +ATGATCCCAGAGGGCACTCTAAAGAAAATGATACAGGCTAAGGGACTAGAGAGGACCTGT +AGAGAGGTGAAGACTGGGGAAGAAGGGGCCCTTCTAGGCTAAGTAGTCAAGAAACCCCCT +CTGAAGAAGGAACATTTCAGCAAGGGCTCACGTGAAGAGTAAGCCATACAGAGTCATGGG +ATTTTGGAACCAGAAGGGACTTTTAACAGATGAGAACACTGAGGAAGAGACAGCAGAAAG +ACAAACACTGGTCTCCCAGTCTTTGCACCTGGGAACCTGCCTCATCTGAGTTAACTGCAA +CCATCACCCACTAAGAGGGACACGCTGCCAAGCCACAGGGACTGGAAGACAGGCACTGGC +TCACCAAGACCCGGCAGTCAGGTCAGGTGAGGAATAACTGGCCAGTGTTAAATCCAGGGA +GGACACCAGATGCTCTGACGTCCATTATCAGATGAAACGGATTAGAGGCTCTCCGGCTCG +CCCAGCCAGTCCCCATTGTCAGCATGGTTTTAGGGAAAGGAGCTTGGAGCTCAGCAACAT +AAAGGCATATCTGACAAAGCCATTCCACTGAAGGAAGCAGTTTGAAAAGTAGGAAGTGTT +CCTACAGAGGGAGGATGCTTCCTGACTTTCCGGAGTGAGATACCCAAAACAGAGCGCTAT +AAAATCTCCGGGGAAATTCTTAATAGGATTGCGACAGTGTGGTGTTTACTTAGATGGTTT +GCTATCTGAGCTCTCCCTGTACACTGTCAATAAGTCAACCAGTGTTTATTAAGTGCCTAC +TGCAAGTCCCCTGGGAACCTTAGAGGCCAATAAGGTGGAATTACAGTCCTCTGGTGAAAC +CAAAGACTTTGTTTCTTATGTTACTTTCTCGTCTCACTTGAATTATAGTTATTTTTTTAT +TTTTCTTGTCCTTATAAAAAAGCTCTTCATGGGGCTTATATAACACAAGTTTATGAACAA +AAATTACTTTTTACTCCCCTTTATATTCCCTACATAGCTGTTTTTAGTTTTCTTGTATAA +AGTAGGCATTAGATAAATATTTGCTGAATTATACTGTTTTCAAGAAGCTAACAGCAGACA +GCAAAGCAATCTGAAATACTCCCATCAGAAAAATTCCTAAGATTTCTGTATTGTGCAAAG +AAGTTAGGGGCGGCTGTTTACCAAACCCTCAAGGCTAATTCTTAGCTTCAAATTCGTTCT +CCTTCTGAAGCCCAGGCACCTAACCCTCAAGAGTGTAAAATAACTCAGCGGACACCTCTG +CAAGCCAGACTTGAGAGTCAGGCTTGAATTTGAATCTGGGCTCCACTCCTTCCTCTGCCA +GAATGCTTCCATGCCACTGTGACTGTGGGCAGATGATGCAACTGCTCCGAGCCTCGGTTT +CCATGTTTGTTGACTGAAGTGAACAGTAGGTCCTGACGAGGCGGCTGAAGCATAAACGAA +GATGCTGCATGAAAATCAGGACATGCCAGTGCAGCAGCGCAATCTTTCCAATTATGAAAC +TAGGGACTTCCACACTATCTGACTTTTCAATCCCCATGTCCTATTAATCCTCAAATCCTG +CCACTCTACTTGCTGCGTATTCTCCCAAATTTGTTCTCTTTTCTATCCAAATTGCCAAAG +CCTCAAATTATCCACTTATTGCATCTCACCTAACTGCTCTCATACCCATTTCCAATATCT +CTCATTCATTTTCTACAGTACTGACACTGGCATCTTTACAAACAAAAATCTGTTTCACTC +TTCGAAAAAATTAAAAGTAAGATGGCTTCCCATTACCGAGAGGATGAAGTCTACGGCCCA +TGAGGTCCTTCACTCTCAAGCCCTGCACTCTACCACACTCATTTCCTACAAGCTCCTCAC +CCTCTGCTTCATATTCCCAGCAAGTGCCTCTAGCCTGGGCACAGGCTACTTCTTTTGCTA +GGATGCCTTTACTGCCTCTCTGGGTGGCAAACGTCTACTCATTCTTTAAGACTCAGTCCT +CAACAATGACAGAAAAATTTGGCTGTGCACTTTTTTATGCTCATATTTCTATTGAAGACC +ATCTTAAATTGTTTGTACATATTCTGGAGTTTCCTAAGGGTAGAAAAGGAATCCTACATA +TATCTACAAGTACTATAACTGATAGATAGTATTGACCACAGAGCCCAACATTAAGTAGAT +ACTCATGACATTTTGTGGGTGCACAACGAATAAATGAAAAAGAACATTCAAGTTAACTAT +TGTTGCTGATGTGTAGAATTTGTTTCAAGAGAATATAGGCTTAATAGCAAATAAAATATG +AATGCTTTTGACAATTTTATGGGTGCTAAACTTATATATAATAGGCTATTGTGTGAAACC +TAAGTAGTCTGGAAGCATATCTCTAATCTGATGAAGGGGACATCACGGATATCCACTGGC +ATGGCTGCCATACAGTGATGGCATGTGCTGGATGGTCCGGGAGCCTGGTATAATTTTTCT +GTCTTTAAGAACACAAAAATGTCCTGATAAGAAAAATAGCGTATTACTCAGGAGGGCCTC +TTTCCTCTGAAATCATGTAAATTTTGGTTTGGTTAGGATCTATTCTGATCTGAGCACAGG +AATGGCATAGACGGGTGCTTCTCAAATCTTTATGCGCACAGAAATCGCTCTTTTCCCGTT +AAAATGAAGATTCAGGTTCAACAGGTCAGGGGTAAGTCCTGAGAATGGTCCTTTCTAACG +GGCTCCCAGGAGACGTTGATGCTGACAGTTCATGGACTGCACTTGAATAGCCAGGTGATG +GGTGGGTCTGTCTCTTCCAATCTCGTGATTCTCCTGTATTTTTATTTTGAAACTCCCAAA +CTATGAAGACCTATAATCTGGTAATAGCAGCAGTAGGATTTTCATCTCTAGGATTTTGTT +AGAACTTTCTAATCTTTAATTTTCACTGACTACCAAGTTTTAATATTTTAAACCTCTATT +TAGGGAGAGGTATGAATGAAAGACATTGCCCATATCCTTTCTTTTTCTAAGAACTATTAT +TATATCCATACTATTTCAGTTTTCTCTTTTCTCTACCTTCTTTAGTTTTTTTATTTTTTT +AGTTTTGAGACAGAGTCTTGCTCTGTCACCCAGGCTGGAGTGCAGTGGTGCAAGTATGGC +TCACTGCAGCCTTGACCTCCCAGGCTCCAGCAATCCTCCCACCTCAGCCGCCTAAGTAGC +TGTGACTACAGGCACGTGTCACCATGTCTAGCTAATTTTTTTAGTTTTGGTAGAGATGAG +GTTTCCATTGGTTGCCCAGGCTGGTTTTGAACTCCTGGCTTCAAGAGATCCTCCTGCCTT +GGCCTTCCAGAGTGTTGGGATTACAGGTGTGAGCCACCGTGCCCAGCTTACCTTTTTTAC +ATTAAAAAAAAAAGTTTATTCCCCCAAGCAGTTTGTGTTTAACACAAAGCCCACTAATGG +ACCAGTGGACTATTTAGGAGACGGTGACAAGATTCAAAATTACACCAAAGTTTCTAGTTT +GTTCATATACTTAACAGAGTTTGCAAAAACACTACCAATAAATAAAATGAGATCAAGAAG +AAACCATTTATTACTACTACAGAATAATAAATTGAATAGAGTAAAAAAAGTGATGCTTCA +TTCTGTGGGCCTAATCCCACATTTACCCAAATATCTGATGGTCTGGAAGCTTCAACTCTC +CCTCATCTTTACCCCCAAGGTCCCCAGCAGTTCTTTTGATGGGTCAGCACTAAAGCCTAA +GTGTTTATACTATTAAAGAATGTGTGGTGGCCTCCAGTGCCAAAGTACAAGACAAAACCA +AAATAGTAATTTTTAAAAACTGTAATAAAGCTAACATAATCCATAGATAGATGAGTGAGT +AGATGTACCAGGGACCTTAAAGAGTTAAAAGGGTTAAACTCTTTCCACGCCCTGGAAATA +TTATTTCCAGAAAAAAGGGGAGGGCACACAAGTATGCAGTTAACTTGTTTTTGTAAAAGA +AAGTAACTTAAAAGGAACAGTCTTCAAGTATGTATTTATTCTACCAGCCCTCTTGTAAAA +TCCAAGGCCCCCCAAAACACACAAAAACACCTCCGGAAAGGTTAGAAAATATTCTCCAAA +GACAGTGGTTCCTGATAATTTAGTAATTTGAGAGCTTGTTTGGAGGTTCTGGCAGGGGAG +CGCAGCTACTCATATACCGTTGACCAAAGACCGGTCCTCCTTCATCGGGGATGGTCATTC +TCTTTGGCCAAGTGCACAGCTTCGGGAGCGATGCACATGGAGCAGGGAGGAAGGAAGGGG +ACACCCGCCTAGCCAGCCAGATCAGCTGAATCAACCCTGGCGATCAAAGGGTTGACAAAT +GTCGCAGCCAGATCGCCCTCACGTCCACAATCTCACGATTTGGAGAAAGAATAAACATAT +CATTTCCTTTTCCTTCTCTGTCTCTTCTCTCCTAGCTCATAGCTCAATGTCTCAGGTGAC +CTCTTCTCATGTCTGAGTTCCTCTTCAATTCAGGATTGAGTCTTCTTGCAAACACCTGAA +TTTATTTTTTGGTCTGTTCTTTACTCCCCCACCATCCCCCCACCAACGATTATGTAATTT +TTATTATTTATTCGTGTATTTATTCATTTATTCATGCATTTATTCATTTATTCAAGTTTT +GAAACAGTTTAAAGGCTGCCAAAGCAAAATAGAAAAAGATCACTCAACTTAGAGTAAGAT +CTGAGTCAAAGATCTAAGTTGAAAAGGTCCTGATTAAACCATGATCGGCTTTGGTACTTT +GAGTGAGCCTCTTAATCCCCTTCAAGCTCAATTACCTCATCTACAAAATGGAGACAATTA +TTCCCAGGATTGTTATGAGATTAAATGAAATAATTGATATGAATGTTCTTTTAAAATTAA +AAAGGTTCTATTTATCTTCAAATAGTGTAAGCCAGTTTCTCAGACTGGTTGCAACATTTT +ATTCGGCAGCAAAAAACACGTCTTGACTTGCTCTTAAAACAGAGATATGTGAAGGAGTTT +CAGCATCAGATTATTCCATCTTTATTTACCTATCAGGTAAAAGATTAGGACCTTATTCAA +TTAGAGACTGATTAGAAGCACAGAGTTAAAGGCCAAGATGTCGATTTTAAAAAATAATCT +CAAAAATAATTGTAAATTCTTAATATGCTTTTTGTTATCCTTCATACACCATATCTGAGG +ACATCAACATTGTTTAATAAACAAAACTGATCAACACTGGTTCAAAGCCGAGCGTGCTTG +GGCTTTTTAGGCACTATATCTAGCAAAGGATTTAAGATGCACGTGTTGAGATCAGAGCAC +TGAGGATCAGGATCAGTTCCTGGGATGTTCTGCATTATTATTTCTGGATTAAGAGATGAT +TAAAGAAAAGTACACTTTCAAAAGGCAAACAACACAGACAGATCCCACAGTCATTTTCAA +TAGTTTATAGCAAATTGTGATGAAATAATACAAGCATGTAAACTTACAACAATTAGAGAG +ATGACAAACCACAAGTACTGATACAATATGGGAATTCAGACCCACAATTATGTAATCCTT +TCCCCCCCAAGGAAGTAAGATACACAGTTAGGTGTGGTTTTTCTTCTCCTATTTTTTTTC +TTTTCTCTTTTTTATTTTTTTAAGGGAAGCACTAAGGAAAAGGCTGCAGCTGGTGAGTGT +CGCGGTCAACAACGTTCAGTGATCATTACACAAGATAGAGCCTGCCAAGAGAAAAAGAGA +TCTCGAAAATGCCTGGTGGTTGTCATTGCTTTGTACGTGTGAATAAACTTTAAATGTGGA +AAATGTTTTAAAAAATTATAGACTGAGTTTGGCTGAAGTGTTGAGTGTATAAATACTTTC +ATTATCTGAACTTATTTTTCTTATTAAATTTTAAAGGGTTTTAAACTTTGGAATTTTTGG +AGTATCTTTTTTATATATGTTTATAGGCGCTCTTGTTTTGCTGAAATGTACAGTTTCATC +CAATTTTTAAAAACTAATTTAAAAATAATTTTAAAAATCTTAGAACTGATCTAACCTCAA +CTCTTGCCTCTCAAGAATGCCACATAATTAACATTATAATGGAACAACTTGATAGGTAAA +TTACTAATTGCTACTAATTTCACAGAGGATTCTGCAGCTTCTTGATTTTTCAGTGATTGC +AGCTACCATAATAATTGGAATATGTTTCAATATCATGGGTTATGTGTCTCTAATAAACTT +TTGAGTTATTTTTCTAATCCCAAATTTTCTTATTGGGCTCTATTTACTGAAGAAAATATG +TTTTATTATTTCCTTTTTCCGATAACTTGTCTCTAAGGTATGTGAAAGGCTTTGTCTATT +ACACATATGTGCACATAAACACACACACACACACACAGAGTGAGAGAGGAGAAATCAAAC +TCAACAAATAGCATATCTTAGAACATTGTAATACCCGGATTTGAATGACTGGGTTAGTAG +GACTAATTAAAAGGAGGGCTGAAGAGAGAAAATTTGACTTCAACAGATGATTTCAGGCTA +TAAGTAGACTTAATAAAGTAAACTGATAACCTAGTTTACCTTTTATGATTAGAGGAGAAT +CTATGCAAATGGTGATTGGGGGTGTCGGGGGGGCCATGGGAGGTTTACATCAGAACCTGC +GCGTGTTCAGAGACTGATGTTCCACTTCACTTTCAGTGATTTCCCCTGTTAAAAAAGACT +AACCTTCTAGAAGGAGAGATATGGGGATTATTTATCACTGTTAGCCCTTTGTGCCATTTA +GAACTGGTGCTTTTTACTCTCAAAGGTAAGTTTTGTTTCTGTTTTACCTGAAATAATTAT +CTACAAGTGAAAGAGTTTAATCAGTTTCCCCTTTAAAAATTCCCTAAGAAGTTAACTATT +ACCAAAAACAAACAGTGAGTGCATAGACAGTCTACAATTATGGTCTTGTGGATTTAGGCT +AAATAAGTGGTATTCTGAATAATTAAATTGTAAAAAACTTCTAAGCAAATTGTCCAGACA +AATTAATGTGGCAACTAATCTCAGCTTAAGCTTTTAAACATTTTCATCAATTTTGCTTCT +AAAACCAAAGAGTTACAACTTTATTTAAAAAGTTTATGTGAGTTTAGGTAAGTCAGATTT +ATCAGGAGTAGAAGGATAGAATATCTTCCTCACTGGGTTGCTGTGAGGGTTAAGGAAAGT +GATGGATGTGGAAGTACCTTGTAAACAATCAAGGGTTATACAAAGATATATTATTATTAT +TAATAAATAGAATCATTTCTGCTTCCATTGTGAAATTCAAAGCATGGAAACAACTTTAAC +ATTAGTTAACAACTGACAACATTACTAAGAAAAAATATAATTTCAAAGAAAAACTTCAAA +ATATAACACAATATACATAAAAAATGTTGGATGGAACTTTTTAAACTCTCAGATTACTGA +TATTTTCAAAACATAATGGGGCACAATATGCATTTATACATAAAAGAGGAATTATGAAAT +ACCTCTACAAATAACAGAATAATATTGAAAATAGTGACTAATTTGAGAGCTTTTTCAGCT +TCTTGCTCAATTCTTTTCAACGTCTCTCACTCAGTAATGTGTGGTCTGAGGTCTGAGGTC +TCCAAACCTCTTAGAATTGTGATTTAAAAAAGTGTGTATGCGTGTGCGTGGGTTTGTGTG +GGTGTGTCTGAATACACACATACATACTTATAATACATTAAAAAATACTTAAAAGCTCTC +TACACTGGGATGAGTATCATAGACAATTACAGTAGATATAATTGTACATTTCAAATCTTT +TTCTGGTTAATTTCAGGGGTGTTTTATAAACAGGGCTGATTATAATGTCATTATTATTAT +TATATTTTTAGAGATGGGGTCTCAGTATGTTGCCCAGGCTGGACCGCAGGGGCTATTCAC +AAGGGAGATCATTGTGTACTACAGCCTCAAACTCTTGGGCTCAAGTGGTCCTCCAGCCTC +AGCCTCCTTAGCAGCTGGGATTATAACTGTGCCACTGCACCTAGCAGAATGTCATTATTT +TTATCTTGCATTAATTTTGCTTCATACATGCTGTCACCTCTGCCGTTCTTTGTTGTTCCA +TGACCATCTGATATCCTGAGTAAGAGTGCTTTCGTTAATTGATATAGTATTAAGTAATAT +TCACAAAACTTGATTTCATTCTTTACAGATAAAAGTGACTATAAATAGATCTTCTGGTAT +TTCCTTCTTACACCATAATGAGGCAATCTTTGCCCCACAATGAGGCAAGGAGGGCACCCC +CTTTTAAAGACCTCTGCTTTACAAGGTTGACACTAACAGAAGCTGAATATCTGTTCAGTA +CGATTTTAGAGGCAATGGGCAACCTTCGATTGTTTAAAAGAGTATCTTGTATCCTCCACT +TTACTGTAATTAAAAGACAAGCTTTTAAATGCAAATATTCACTGGGTCTAACCTTGCAAA +GATAATTTCAAATGTCCTTTTCTAATTCCTGGACAGCTTCTGATAGTGTCAACCTTGTAA +AGCAGAGGTCTCTAAAAGGGGGTGTCCTCTTTGCTTCATTGTGGGGCACAAATTGCCCAT +TATGGTGTAAGAAGGAAATACCAAAAGATCTATTTATATTCACTTTTATGTGTAAAGAAT +GAAATACACACACACACACACACACACATATATTTTACATATGTTTTATACATATATATG +TATAAAATAACCCCTTCTAAAATGTTGTCTTAAGTGATCTGGCTTTATCTAGTTATTAAA +ATATCTTTGTAAAATGTTAGCTGGTATCAGTTTACCCATTTCCCATTGCAGAGATATTTT +CATATTTATAGAGGACACTGAAAAATAAAATTAATTTAAAAGTTAAATATAAATTAATTA +ATGTAAAAGTTAAAAATAAAATTAATTTAAAAGTTAAAAAAAAGCATATTTTTTCAGGTA +GTGTTTTGGTACCCTGAGAGGCCCTGGGAGCAGGGTGGCTTCCCTGGTACCTCTAAGGCC +ATCTCTCATGTAACCCATCTGTTAGTTCTATTAGTATGGTGAATCCTGCTATTGCTATCA +TTAGAGTGTTAAATGTTTATCTCTCATTTAAGAGGCAGTTTTCTTTTTCCATAAAAAGTA +ACATATTTTCATAGCACCCGAAGAACTAACAATATCAGAGACTCAGGGAGGCACAGAGTT +AAACGACTGATGTTTTTCCCCAGTTTACTACGTGTCTTAGCTAGCGCTGGTGTTTCTGAT +CTGTCCCACTGTTGGCAACAAATCTCTCTTCAATTACAGGATCCAGCAGTATATATTTCT +AATATATAAATTATAACCATCTACACTCCAGAAGTCACCATACACTTGTAACAGCTAAAT +TGGACAAAGTAATCCTAAATAAATCAATCAGGCCCTATTATACTGGTTTTTCTCTCTTAA +ATATAGTATTTTCAAGTAAGTACCACAACACTACCCCTAACTGTCTGCCAACAGTTTGTT +TGCCAACTGCCAGGATAGGGCATTGTCTGTCTTGTATATACCAATTTGTTCATAGTTCCT +ACATTATAAATTTTAAAAACAGTCATGGTGATTTCAAAAACAAGATGTCATATTTTAGAG +GTCTAATTATGAGTTCAGATTTTACTGCTTATTTTAGAAAATGTTAAATTTCAGGCTCAT +ATTCTATCTACATCTGTGTATATAACAGCATTGCCTCAGAAGACAAGATATGGTGATTTT +CAGTTGTTGATAAAACACATATTTGAATATAGTCCATATTTTTGGCTATGTTTTTAGATT +GTGGAATATATGTTCTCAGAGCACACAGCTGGAAGAAGAGGGTGTTTACCTTGATTTCCG +CTTAGAGAGAAGAAACACTGACAGAAACTTGTACAGTCTCCATTTACTTCAGCTGGTCAC +CACTATTTGTGATATTAGCTGAAATCATTCCAATTAGAAAGCAAACGTGCATGCATGTTG +TGAATTGTTTTTATAATTTGGTTTTTATATTTAAAAGTCTCCACGCTGTGGAGGCAGTGT +CTAAGAGTTCCACTCAAATGAGTTGATTCCCAATCACGCGTAATCATATTTTTATTGAGT +ACTCTCCAAACTTTATATAACCTTACCATTATTCCTAAAAAAGTTTTTCTTTTAACTATA +AAAAAGACGGCAAATTATTTTAAAAGAAGAATTAAAAGAGACATTTGATAAATTATACAT +TTATACTACTACCTCTAGCCACATTTTTTTAAAGAAAAGATTCATTTTAGAGTTTTCATA +AGTGAAGCTAAAAATAAATACTTCAGAGAAATATATAAAATATTAAATGTGTCATGTTCA +AATTTGTTACAGAAAAAATTAACAAGCGAAAACCAAGACCTATTAACTAACTTACTAAAA +TAAATCAGTTTCCAAAGGATATGGAAGTTATTGAAAGAATGATGACATATATCTTGAAAG +TTTCTATACTTTTCTCATAAACTTGAGGTTTGTGGACTTTAAAGTGAAGTTTAAATCAAA +GTTAACTCAATGAGTTCCTTGAAAAAAATTGGCATTGTAATAGGGCCAAATACCCAGCTG +TTCTGTGGCCAAATTTGTCTCTTTATCCCAAAGTGAAAAATCTACAGACCATTTTGCTAG +TTTGCTTTTATACCACATTGATCAAATTTGTTACCCTTAATTTTTAAAATCAAAACAAGC +CACAACTTTTTTTATTGGGGGAATTAACATTATATATTACATGTTTTCCAAATATTTCAA +AAGACTAAAATTCATGTGTTTGTTGGTTTGCAGTTTTTAGTAAAGTACCAGAAGGAAGGG +GAAAGGTGTGGATATTGCTTCTTTGGGTTGTGTGTTTAGGAAGGAAGCAGCCAAGGATAC +ACCTGCTTTTGGCACTGGCTTAGGCACTGGTACAGCAAATGCCAGGTGTCATCTCAGAAG +AGGCAAGAAATACGTGAAATACACACAGCCAAGCAAACAGACTTACACTGAAATGGTGTG +ATTTTCAACAAAAATATAACTGAGTTTATGGTCAACATACCACCATGTGATACAATAAAG +TATTAGCATTCTTGTTTTTCTGTCTCATACTACATGATTATTTTTTAACAACAGCAGCAA +AGTATTTACTTTTTTTTTCTAGGAGGAAATTAACATGGAAGCTTGACTGCATGCATGCTG +AGTGTCACGTAATGTTACATTTGTAATACAGTGGAAAAATACAGCAGAATTTATCCTAAC +TTCAGGGAATAAAATGCAAAGTATTTTAAAATAGAGTATTTAAATCCTGGAGGATTTGAT +TTTAAAATCAGCTTTCAAAGCAAAGATTTTGTGGGGTTTACTATTTACTATCAACCACGC +TGTGGCTTCTATTAAATGATTATGAGCCCACAGGGGAAGAATAAATTGTGTTCTTTAGAA +TAATCATTCTAAAATAAACATTTAGAGGTTCTAGATATTATTTCAGGGTCAAATGAATTA +GTTGAACTATTTTGTTGGTTATATTGGGTATCCCTGCCTTTGACCCAATACAGATGACTA +TGAGACATATTTTCTTCCAAGTGATTAGCTGATGGCCACTGACTGGCAAGGTTCAGCTGC +TACTATAGGTGTATAGGTCCCCAAAGCAAGACCTGACAAGAAGGCAGGTAGCAAAAAAGT +GAGACAGAGAGAGAGAGAGAGAGCACTACTTGGTCACTATCGACCACCTTATCATGGAGA +AACTAAGGAAAGGAGATTAAAATAATCTTAATTAGCACATATGATGTGTAATTCACACTC +TGTTCCTATGCTCTCGGTTGATTCAGTCATCATTATTCCATTTCCAATATCTGCTCATCC +ATCATACCAAAATGATAAGTCCTAACGACGACAACAAAAACACATTCAGTTTTAAAGTAA +AAATTCTGACCTCTAGATAGGCTGAAGAGAATTGCTATAGAAATAAATATAGGAAGAGAA +GAGATACACTTTATTTCTACTTTTCTCCCCTTCATGTCAAATAATTTGTTAGAGTTTTAA +AATACATTTTTCTCCCTTCCACAACAGAGTCTGGTCGATAAATCCAAGTGAGAAAACTAA +AATCTGAAACAACAAGGTTCACGCAGCCAACTAGAAAAGTCTCTACATTAAGCTGACGAC +TGACCTACTGTGGCTATTTCCAAGGTAGCATTCCATCGACCTGGTATTGGCAATGTTGTG +ACAATAGTCTTTACTCTTTAACATTCATACTTCACCATATGAATGTTAAACAGACCCAGG +ACAAATAAGCTGAGGGTGGGGGCTTCTCTTGTCCTTAGAAGGATATTTTTCAATTACATA +TTTTGTTACATCCTAAGAGATAAAAGCTGTATCTGCAAGTGATTAAAAGATGTTTTATAT +TCATGGTTTCATTTCTGCTGAAATAAATGCGTAATTTAAACCAAACATAATTCATAGCAA +TTTAGGCCTATTACAGAGTTCTAGCTTCTTTTTTATGATAGTTACTAATTAAAACAGAGT +GTTACTGCCACACTAAGCCTAAGTCTTTGACATACAGGTTTAATGAATAAAATGTCCTGA +CACAAAAATGAAAGCAATAATGCAGACAAGGCTGCAAGCTGTTATGTTTCAAGTGTGTGG +TAAAGATTAAGGGCATTCACTGAAGTGATGAACTGTGCAGAGAAGGACCTTGTAATTTCT +TTCTCTAAAGGAAGAAGTAAAGGAATTTTTAGAGAAATCTGAAATAGTACTAATTTATCT +AACTCCTAGGCCCCTCATTCCCAGTTGTCCCTCTCTCCCCTCCAAGAGTTTAAACTCATA +AGAGTCACTTCTGAGGAATAAATGATGGGGTATTTTAATATAATCCTGAATATAGGTTTA +GATTGAAAATGGGAATTGGGACCATAATTAATTATGTTGCCAAGTTTTTTAAACTTTAAG +AAGACAGATGGAGGCAAATGACATTTTATAAGAGTGCAACCTTCTAAAAGATCATAGATT +AAAACTGTGGTAAAACGACAGTATCTTTTTTGACATTTGATTAATCCCATATGCAGAATG +ACTGAAGAATTAATACGGTTTTGGTGTTTTCACTTTCTGAAACCACTGTAATAAGAGACT +GACATAAACTCAAACCCCAGTATAAACACAGTCTGAGCGAAGGTTGCGGCCTTATTATCA +CTCTTAACAAACAATAATGAATAATCATACCGATCGCCCTCACTACACTCTGCTTTATAT +ACATATTCCCTCTCGGATCCATCCATCACTTCTTTCAAGATAATAAAACAATTCAATCCC +ATCAAATCCCCTGCAACCGCTCCCTTGGGAGGGATGTTTTATCTCTACTTCTCCGAACCC +AGGGAGGATTTTACTTGTTTGAAGGGGGCGGAGAATGGAGCGGAGTCCTATTTATTTCCA +TTGATGACTCCCCTGGTTCTCACAGGCGCTCAGGGACCGGGTGGGAGGAGGAGAGGAGGA +GGTGCGGAGATTCCCTCCGTCAGAAAAGAAAAAGGGTTCAGGAAGCGAGGCAGCAGGAGG +AGGGGTGGAGGGGGGAAAGAGAGGGTAGTGTGTTTGGGGAAAGCAGCAACTAAATGAAAA +AATAAACTCTTCTTTGTGATTTAGCGGGATCGACAGATGAGAAGCAAATTTATCAACCCA +ACAAAGTTGCTAAAAAGAACTCTGTAAATAAATTTAAAGAAAAGAAGGAAAAAACATAAC +AACAACAACAAAACCCAGACATACACTCAGGTTCATTTCCCGCTCAAGGTCTTGGTTTTA +GGGAGCCACCCGTACCCAAGAGCAAGAAATGGACAGCGCCCCGAAGGGGGCCAGGAGGGG +AACCGCAACTTGGCCGGAGGGACAGCTCAGAGACAGCGTAGAGGTGCCCGCGGCAAACTC +CGAGGAGCTGATGCGGGGCGGGTCCGGGGAACTGCCGGGAGCTCTCACGCCTGGGCCTGG +GATAGGGTGCGGGCAGAAAGGTGAACCGAGAGCGCACAATGCAACGAAACCGCACTCCAA +ATTCAGCAGTTTGCAAAGTGCCTCCAAGAAAACAGCTGGGACCTGCAATCACTCGTTCGG +ACTCCTAGGTTATCGGGGCCGCGGCGACTCCGCTCAGTTAGAAAGGTAGCGCGGGTGAGA +GCGAACCCCAACTCACGCACAGACAGGACGAGGGCACGAAGCCGAGTCTCCTGGCTGGGG +CCGTAGGGGGCGTCACCTCGGTGGCCGCTCTGCTCTCCGGAAGAAAGTATGAGCCGGTCC +CAGGCCACCTCGCTCAGCCCAAGGAAGTTTCTATAACGATGCTCGCCTACCACGCAGAGG +ACAAATGAGGAGCCAGAGCGGTTGGGGGTCGGGCCAACCGAACTCCCGGCCCCGGCTGCG +CAGCTCCCAGACGCCCACCAAGAACTCGTGCGCTGCCTGGACCTCTAGCTTTTCGCCCTA +CACGCAGACGCCCTCTGCAAAACCCCAGTCCCGCAGACTTTCCCTAGCGGCGGGCGGAGG +GCATGAACCTGGAAAGGGAGGCAACAGCCCTCTTGGCAGGCGGGCAAAGTAAGTGTCCAG +GCTAAGTCCGGGATAAAGGCTCCGCGGCTCCCCAGACCCCACTGCACCCCGAGCTCCCGG +GTCCCAGGTCTTCCCCGCCCTTGCGCTGTCTGTCCACCTCCTCACATCTCTCCGGGCCGC +CCAGCTTCGAAAGCAGCTAAATTAAAAACAAACAAACAAACAAACAACAACAACAATAAA +AAAAAAAAAACGAGGGAAACCTGCTCCTGCCCCTCATGCCCTCAGCTCCTACGGATAGGG +CGCCCTTGAGAAGCTTCTTGGGCCTTGAAGATTTGGGGGCGCGTGCCTCGAGCCCCCATC +TCGGATGACCCTTCGGGCGTGAACGCTCCTTGTGCTAGGTCTCAGGGTGGCGGGCTAAGG +CGTCGGGTCTCTGGGGCATTGCTTTCCTCTCCCCACTTACCTTAAAAAGATCTGTTTTTC +GTAGGGAAAATAGAAAAAAATCCCTCCCCGTGGTGTGGTGTGCGAAATAGTCCACGTCCC +CGGACCCTGCCAAGATGCTAAGCACCAATATCCAGGAACGAGAAGCCTGGAGGGCGGGGA +CGGAGGCAGATAAAAGAGAAAAATTCAATCCGCTGAAGTGTCCCAACTTTGCGGTCGGCA +CAGCAAACTTCAAAGGCGGGCGAGGGCGGGCGGCGCGCGGTCGCCGAAGTTGCTGCGAAG +TGGAGTAGGGAGCCGCGCGGGGCTGGGGAATCCCGGGGCAGCGCCGAGAAGCGGCGGGAG +GTCCTTTTAAACTGCAGGGAGCGTGCGGGGGCTGGGCGGCGGGAGGATGCCGCAGCGACC +CGCGGGGCTGGCGCGGGCTTCGCCGGCCGCCGCTAGTCGCACAGGCGCCTGGCTGGAGCG +CCGCGCGGGGTGCTGGGAGAGCCGGGCGCACGGGGCGGCAGCGGCCGTGGCGGGTGCGCT +GCTCAGTTAGCTCCACTCTCTCGCGGCTGGAAGTGGGGAGTGTGTGTTCGCTCCCGAGTG +TCACTGCTGAAGCCCGGAGTCTCTTCCCCTCCCAGCCCTAACCCCTCCCGCCTCACCGCT +GCCCGCCCGCCCCCTCCCTCCTCTGCCCGTTGCCTCCCCCTCCGTCCCTCCTTCTCTCCC +TCCCGCTGCGCGCCAGCGCGCACGCACACACACACACACACACACACACTCATACACATA +CACACACTCACACACAGACACCCTCTCCCTCCTTTTCTCTCTCCCTGTAGCCCTCCCTCC +CTCTCTTTCTCTCACACACACACCACCCTGCTCAGCGACCCAGCGCTCCCCAAACAGGAC +CCTCGCGGGCGGCATCGCGAGGGACACGCTGCTGTCCTAACCTTAGCGCCACTCGGGGAG +AATGAAGGAGGCCCACCGAGCCCCCGACAAAGCTGCAAAACCCAGGAGACGCGCACGCGG +GACCATCACACTGTCAAGCAGACCGGGGTGCACAATAGAGGGAAACTCTGGGGTTGATCT +GGGGGCAGG diff --git a/test/csq/ENSG00000173376/ENSG00000173376.fa.fai b/test/csq/ENSG00000173376/ENSG00000173376.fa.fai new file mode 100644 index 0000000..93ec72b --- /dev/null +++ b/test/csq/ENSG00000173376/ENSG00000173376.fa.fai @@ -0,0 +1 @@ +4 37449 25 60 61 diff --git a/test/csq/ENSG00000173376/ENSG00000173376.gff b/test/csq/ENSG00000173376/ENSG00000173376.gff new file mode 100644 index 0000000..9114e34 --- /dev/null +++ b/test/csq/ENSG00000173376/ENSG00000173376.gff @@ -0,0 +1,22 @@ +4 ensembl_havana gene 21 37429 . - . ID=gene:ENSG00000173376;Name=NDNF;biotype=protein_coding;description=neuron-derived neurotrophic factor [Source:HGNC Symbol%3BAcc:26256];gene_id=ENSG00000173376;logic_name=ensembl_havana_gene;version=9 +4 ensembl_havana transcript 21 36926 . - . ID=transcript:ENST00000379692;Parent=gene:ENSG00000173376;Name=NDNF-001;biotype=protein_coding;ccdsid=CCDS3717.2;havana_transcript=OTTHUMT00000256532;havana_version=2;tag=basic;transcript_id=ENST00000379692;version=4 +4 ensembl_havana three_prime_UTR 21 671 . - . Parent=transcript:ENST00000379692 +4 ensembl_havana exon 21 2065 . - . Parent=transcript:ENST00000379692;Name=ENSE00001740431;constitutive=0;ensembl_end_phase=-1;ensembl_phase=1;exon_id=ENSE00001740431;rank=4;version=2 +4 ensembl_havana CDS 672 2065 . - 2 ID=CDS:ENSP00000369014;Parent=transcript:ENST00000379692;protein_id=ENSP00000369014 +4 ensembl_havana exon 4338 4462 . - . Parent=transcript:ENST00000379692;Name=ENSE00001611953;constitutive=0;ensembl_end_phase=1;ensembl_phase=2;exon_id=ENSE00001611953;rank=3;version=1 +4 ensembl_havana CDS 4338 4462 . - 1 ID=CDS:ENSP00000369014;Parent=transcript:ENST00000379692;protein_id=ENSP00000369014 +4 ensembl_havana CDS 10058 10245 . - 0 ID=CDS:ENSP00000369014;Parent=transcript:ENST00000379692;protein_id=ENSP00000369014 +4 ensembl_havana exon 10058 10246 . - . Parent=transcript:ENST00000379692;Name=ENSE00001784917;constitutive=0;ensembl_end_phase=2;ensembl_phase=-1;exon_id=ENSE00001784917;rank=2;version=1 +4 ensembl_havana five_prime_UTR 10246 10246 . - . Parent=transcript:ENST00000379692 +4 ensembl_havana exon 36401 36926 . - . Parent=transcript:ENST00000379692;Name=ENSE00001205012;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001205012;rank=1;version=4 +4 ensembl_havana five_prime_UTR 36401 36926 . - . Parent=transcript:ENST00000379692 +4 ensembl_havana transcript 1944 37429 . - . ID=transcript:ENST00000515757;Parent=gene:ENSG00000173376;Name=NDNF-002;biotype=protein_coding;havana_transcript=OTTHUMT00000364461;havana_version=1;transcript_id=ENST00000515757;version=1 +4 havana exon 1944 2065 . - . Parent=transcript:ENST00000515757;Name=ENSE00002059010;constitutive=0;ensembl_end_phase=-1;ensembl_phase=1;exon_id=ENSE00002059010;rank=4;version=1 +4 havana CDS 1944 2065 . - 2 ID=CDS:ENSP00000423352;Parent=transcript:ENST00000515757;protein_id=ENSP00000423352 +4 havana exon 4338 4462 . - . Parent=transcript:ENST00000515757;Name=ENSE00001611953;constitutive=0;ensembl_end_phase=1;ensembl_phase=2;exon_id=ENSE00001611953;rank=3;version=1 +4 havana CDS 4338 4462 . - 1 ID=CDS:ENSP00000423352;Parent=transcript:ENST00000515757;protein_id=ENSP00000423352 +4 havana CDS 10058 10245 . - 0 ID=CDS:ENSP00000423352;Parent=transcript:ENST00000515757;protein_id=ENSP00000423352 +4 havana exon 10058 10246 . - . Parent=transcript:ENST00000515757;Name=ENSE00001784917;constitutive=0;ensembl_end_phase=2;ensembl_phase=-1;exon_id=ENSE00001784917;rank=2;version=1 +4 havana five_prime_UTR 10246 10246 . - . Parent=transcript:ENST00000515757 +4 havana exon 37302 37429 . - . Parent=transcript:ENST00000515757;Name=ENSE00002032155;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00002032155;rank=1;version=1 +4 havana five_prime_UTR 37302 37429 . - . Parent=transcript:ENST00000515757 diff --git a/test/csq/ENSG00000173376/synon.txt b/test/csq/ENSG00000173376/synon.txt new file mode 100644 index 0000000..b84a16d --- /dev/null +++ b/test/csq/ENSG00000173376/synon.txt @@ -0,0 +1,3 @@ +1944 T C synonymous|NDNF|ENST00000379692|protein_coding|-|145L|1944T>C,synonymous|NDNF|ENST00000515757|protein_coding|-|145L|1944T>C +1944 T C synonymous|NDNF|ENST00000379692|protein_coding|-|145L|1944T>C,synonymous|NDNF|ENST00000515757|protein_coding|-|145L|1944T>C + diff --git a/test/csq/ENSG00000173376/synon.vcf b/test/csq/ENSG00000173376/synon.vcf new file mode 100644 index 0000000..0883de8 --- /dev/null +++ b/test/csq/ENSG00000173376/synon.vcf @@ -0,0 +1,7 @@ +##fileformat=VCFv4.2 +##contig= +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO +4 1944 . T C . . EXP=synonymous|NDNF|ENST00000379692|protein_coding|-|145L|1944T>C,synonymous|NDNF|ENST00000515757|protein_coding|-|145L|1944T>C;type=ENST00000379692:121958691-T-C diff --git a/test/csq/ENST00000218032/ENST00000218032.fa b/test/csq/ENST00000218032/ENST00000218032.fa new file mode 100644 index 0000000..6450bce --- /dev/null +++ b/test/csq/ENST00000218032/ENST00000218032.fa @@ -0,0 +1,278 @@ +>X X:12924719-12941308 +GCCATTTCAGGAAGTTAGCCAGTTTCTCTTCTCGGCCACCTCCTGCATAGAGGGTACCAT +TCTGCGCTGCTGCAAGTTACGGAATGAAAAATTAGAACAACAGAAACATGGTAAGCCACT +TCTATTTCTTTAGCAAAGCTTTCCAACAGAATATGGGGTTTCTGACCCAGAAATCTGGGT +TGGTGGCAAATGGTGTGAGCCTAGAAAGTAATAAATGGGCAAATAAGGATAAAAATTAAA +GATCGAAACAACTGTAAATGCAGGTAAAGCGGCTTGCTATGATCTTTAATTTGTGCACAC +GTTAGTATAAAGGAATTAGAGAGTAAATTTTGAAAATCAAATGCAGTGATGATCTTACTA +ATTTGGACAGGAAAATAAGAAAATTTCAAGTTAGAAATTGAACTGGAAATATTACTTACT +GGCCCTACCAGAGACAATATCCTCTTCCAGAACAACAGGGTTGGAAGAGAAGGTGAGGGA +AATATTCTTCCTTTGCTATTTCTGTAGAAAAGGACAAACTCTCTTCCTTCACATACATAG +GTCAATTGCTAGATCCTAGTGAAGCCTGAGCTTAACCTACTGTTGGAGGCTTAAAGTTCG +ACATTAATTGCTACTTTTCTTGGTCAGAGTTTTAAATAATTAGGTTGGTACAAAAAACTG +TGATTACTTTTCCACCAACCTAATAACATGCTACAATTTCTGTAATTATTATTTTACACT +GTCAAGACATAGCAGGTGGTCCGTTTTTGTTATTGTCAAGAACTGTCAGACTAAAAATGA +ACTTTACACTTCTTTTTAAATGATACATTTTCTAGAAAATTCAATGAGGTTTAAGAGCAA +TTGAAAAGTCTGATTTCAAGAGAGTCTCATCCAAAATGTACTATATATTTTTCCCCAAAG +TCCTTGGAGTTAATTTTGACAACAATTTAAAGTACACTTAAGTCTTTTGAAGTTAATGGG +TCTGCCACCCAGGTTGGAGTGCAGTGGCGTGATCTCAGCTCACTGCAACCTCCGCCTCCC +GGGTTCAAGCGATTCTCCTGCCTCAACCTCCCAAGTAGCTGGGACTACAGGTGTGTGCCA +CCACGCCTGGCTAATTTTTGTATTTTTAGTAGAGACGGGGTTTCTCCATGTTGGCCAGGC +TGGTCTCGAACTCCTGACCTCAGGTGATCCGCCTGTCTCAGCCTCCCAAAGTGCTGGGAT +TACAGGCATGAGCCACCGCGCCCGGCCTGAAGTTAATTTTTATACCCACCTAATGTTCAT +TATGGATCTTGAAGGTAAATTAATTCTGCACTAAAATTTTACAATGCTTTACAAAATGAC +TGTAGGTGGCCCATATGGAATTCGGTCAACTGGGCCAATGACACATATGGGATTGCAGTT +GAAATTATCCAATTCCTACTTGATATTTGTAAGCTGCTGTGATAGCCAGTATAATTGTAC +TGTAAGAATGTGGTAAATAGCCGGGGCCCGGTGGCTCACGCCTATAATCCCAGCACTTTG +GGAAGCCGACGTGGGCGGATCACTTGAGGTCAGTAGGTAGAGACCAGCCCGGTCAACACG +GCAAAACCTCGTCTCTACTAAAAATACAAAAATTAGCCAGGTGTGGTGGTACGCACCTGT +AGTCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATCGCTTGAGCCCATGAGGTGGATGTT +GCAGTGAGCAAAGATCGCACCATTGTACTCCAGCCTGGGCAACGGAGTAAGACTCTGTTT +CAAAACAACAACAACAACAACAACAACAGATTGGTAAATAGAGTAATAATAAAATCAAAT +TAAACTTGCAAAAAATGGCCACTTTGCTCCCACTGGTGGCCAATGGAGGTCAAGGACCTG +GCTGACCTCCTGCCTAAAGGCAGAGGTTGTTAGCCTTCGCAATGGACTCAAATCAGAGGG +GGAGCTTTCAAAACTCCTGCTGCCCAGACTGAACCCCAGATCAATGAAACCAAAATCTCT +GGATACAGGGCTTGGCATTTGTAGCTTTTAGAGTTCCTAAGTATCTCTACTGTGCAGCCA +AAGTTAAGAATCAGTGCCTTAGAACATCAACAGTTTTTTGGTCCTTTTGTTAAAAAGCAC +AGTCCGTTTTTTTAGGTGGCTAGAAATGCTCCAGGAAGAGCTGAAATGTATTTACCAGCC +ACCTTGGTTTGATTTTAGAAAGCAAAATAGAAGTTCTAAGTATGCTTTCTCTGAAAAGCT +GAGACTGCAGATAAGAGTGAGGGCAGTTGATGGAGTTCATTCTCCTCTTTCAATCACTGC +TTCTCATCCTTTCATTATAATAATCTAAGAATCTCAGAGATTATGAAAGAGAAAGCAGTC +TTATGGAAGACCCCAGACTCACAGAATATTAGGGTGTGTTTCACAGGGAAGGATGTCATT +ACCCACAGTTAGTCTTTGAAACGCAGTTGGACATTATTTGTAAGTGCATCATAGTGTCGC +CTCCAGGTTCCATTGAGGGGAACGTCATTCCAATGCAACATCTCTGAGTTCATCTGGGTT +ATTAAATGGGGTTGAGGGATTTGTTATTTTTAAATTAGTAGCCCCAATTTAGGACTACTC +AAGACCATAGGACAAGCCTGTCCAACCCTCGGCCTGCGGGCTGCATATGGCCGAGGACAG +CTTTGAATGCAGCCCAAGACAAATTCATAAACTTTCTGAAAATATTATGCATTTGTTTTT +TAGCCCATCAGCTACTGTTAGTGTTAGTGTATTTTATGTGTGGCCCAAGACAATTCTTCT +TCTTCCAGTGTGGCCCAGAGAAGCTGAAAGATTGGACACCCCTGCTATAAGACACAGTAA +TATAAATACATAACCTGTGGTTCTGGATTGGCATTAGCAGATACAGGCTGTGTTGATTTT +GCAGAAAGTTACAAAGAGCTGCTAGTTGGTGTGTATGTCTAAAATCAGTAGATTTCCTGT +GGTTCTAAGGAATGACAAAGAATCTGGAAGTTCTCTGTGGTAGCCTGCTCAGTGCAGAAA +GGGAACGTGGAAAATCCGCCACCAGCATTTGAGTCTTGGAGGTTCCACATAGGGCTATCA +GGTCTCTGCTGATCACTGAAACCAGATCATGGCCAACTAGCCCCTTGGCTTCAGCCCTCC +CAATTCATTAACTACTCAGGTAAATCTAGGGTCACTTTCAACTCTACCACCTACCATCTG +AGTGACCTTGAAAACATTCATCTCTCTGAGCCTCAGGTCCCATGTCTGTAAAGCAGGGGC +CTCATGGACTTCTTTGGGTTTTTTTGTTTTTGTTTTTGTTTCTGAGGATTAAACAAATGC +TCCCTACCCTATTTCCCAGCATCCAGTAACACAGTTTTTCATATTTTTGTGTATGTTAAG +TCAGGACCCATCTCTTTAATGATAAGTGCACTTAATGTGGTCATGTTTTCTTTTGTCTTC +CAAAGCTGTTAGTGAATCCATTGAATTTGGGATGGGTAAAATAAAGTATCTATTATTAAT +TGTAAATTTCATCTAAAGTGACAAATCCTACCTGCATAACCATTTCTTAATTTCCTTTCA +TCATGTATCAGTGGTCAACATTGTTAACTGCGAATGAATCAGAATCCATCAAAAATTAGA +ACTATTTCCAGTCTGGCAAAAATTCAGCTCTGGTTGAATCCAAACATTGTGCTGAAGCAG +CTAAGTAATTCAACTGAGGAGATTAATTACATGTTATAATCAATAGGTTCTCTTGACACT +TCAGTGTTAGGGAACATCAGCAAGACCCATCCCAGGAGACCTTGAAGGAAGCCTTTGAAA +GGGAGAATGAAGGAGTCATCTTTGCAAAATAGCTCCTGCAGCCTGGGAAAGGAGACTAAA +AAGGTAAAAAGCTGTTAATTCCAGGAAGACAGCTTTACGCCCCTCCCAGACCACCTGCAC +TGCACACTACGTGGAATTTATTTTAGTCTCACATGGCAGCGTCCCTACCTTTGTGCCCAC +ACATCTGGTCTCCGCCCTGGCTGCAGCCCTCCCCTTCAGGCGAATTCTGGGTGTGTCCTA +TCTGCTCATTGCAACTCCCAGCGAATGAGTTTTCAGCGAAGGCAGACTTTCTGACCTGTT +CTTCAAACTGCACTGGTCTTTTAAAAACGTGTTTGGTGGCCATCAGCATCCAATTTCAGA +AGAAAGATTTGGGTGAGGACTGAGAGAGGCTGTTGTTGTTGTGCTGTCTGTTTCCTTCAG +AATCTGCAGAAGAAAATTGGCAGGTCATGTACTGTGGACCTAACCAAAGGACAAATGATG +TATGGAAAATAGAAAAACTGTTGTGAAATTGCTTCCTCATTAGCAATAACTGTATTTGGC +AGGGAGAGGAGAAGTTGGGCACATTTTTTTTTCTTTTTTTTTTCATGATTCATACGTTTT +CTTTAAAGAAGTGGGTTTTGCTTTTCACTGGGTGCTCTAAGACAACCCCAGTGAAAGATC +TGGACCACGAAGACCCAGTCATCCTCATAAGGGTGTTCATTGCAGCAAGCTCAAGGGCAT +GCCAGGCAAAGGCCTTTTTTCTGGCAGCTTGAACTTGTCTCAGCAGAGGGTTTCACAGAA +CAACTGTCATTTACCTGTTCTCTGCTCTTACTTGATTCGTTTCCCAGGACTGCTGAAACA +AAGTACCACAAACTTGGTGGATCAAAACAGCAGAAATATATCCTCTCACAGTTCTGGAAA +CCACAAGTCAGAAACCAATGTGTTGTTGGCAGGGTTGGTTCCTTCTTAAGGGGCTAGAGG +GAAAATCTGTTTCATGCTCCTCTCCCAGCTTCTGGTGGTAGCTAGCAATTCTTGATGCTC +TCTGGCTTGCCGCTGCATCTCTCTAGCCTTCACCTCTCCTCATGTGGGTGGCCTTCTTTC +CTGTGTGTCTATTTCCAAATTCCCCTTTTCTTATAAGGGGACCAGTTATTGGATCAGGGC +CCACCTTAATTCAGTAGATCCCATTTTAACTTGATGACATCAGCAAAGTCCAAATAAGGT +TGTATTCACAGGTACCAGGGGTTAGAACTTCAAGTTATCTATTAGGGGACACAATTCAAC +CTAAAAACTCCCCTTTTTTGATTCTCTATTCTGCCACTTCTACTCAATCCAGGTTCTTCA +CTTCATCAGCTCCCAATCTAATACTTATCTTATTTCTAGTAAGCATCTCTTCCTTATCTT +AACTGGTCCCTGGGGCCTGGCCCGAGCCCCATTATACCATCAGCTGTTGACATCAAGGGT +GGACTTCTCTTTCGGCACAGAAGGCACAGGGCTGTAGGCTTCAGCCTTCTCTGCTTTGCT +CTGCCCCATCTACTGTTCATCCACCTGCTTTCCATTTTGCTAAACTTTGTAGAAAATTCT +TGTCAGCTGTTGTCTCCTCCTACACTTTCTTTGATCTTAGAGGATTCTATTCTTTTACTA +TGGCTTTAATCGGAGCACCCGACTGTTAGGTTCAACCAACAGAAGTTGGTTGTGCTCTCT +CACTCTTTCTTTCTCTCTCTCTCTCTTTCTCTCTATTTGCATAGTGGTATTTTTTTTTTC +CTCTATTTTATTGGCAGAATTGCCATTTCTCTAAGTTATTGTAGAGTTGCTGTTTCTCTA +TTTTATTTGCATATTTCTCTTCTGCCAGGCTGGATTGTTTCTATTGATTGGTTCTGCTGT +AATGAGGGTGACTTCTCATTAGTATCCTTCTCACTTCATCTGGGACCAGATGCCCTTTGA +TATCCTTTTGGAGCCACAACTTTTGGTAGTCAGAGGCATGGGTGTGGCTCAAAGGAAGAA +CTTGGCTCAGAAGGTGCAGCTCTTGCTGGGCCTTTGGTCTCTGCTCTGTCTTCTGAGATC +AGTGGCTGCTGGGACCTGGGGTTCCCCCATGCCGGGCATGGTCACACAGCACTCCTATGG +ACTTGAGCAGAGCACCCTGCAAAGTGAGCATTAGCAATCCATTCCAACTCTGTGCAGTCC +TGCACGGAATATAGAAGGTGGAGCAATGACAGTCTCCCCAACTTCTCTGCAAGCAACCTG +CTCACCATTTCTTGCCCTTCCCATTTATGTACTTTTCAAAATCAGGTTATTTGGAATTTG +TCGACTCATGTTTCTTACTTCAGTACTTTTTTGGGAGGGCAGCATTAGAAACCTCAAACT +CTTAACTAAAAAATGTCTTTGGGAATGTTCTGGCCATTTTCATGGCCCACAATTTGCTTT +AAGCTGCTTTAGACTCTCCCAGAGGCTATTTTCATCCCGAAAGAACAGAGCAGAGCTCAA +AAGACTCCAGTTTTGGTCTCTAGCAGCCCCTAGAGGATTTCCCCCTCAATTCCTCTCTGC +CTTGTATGAAATAGAATTGGATTTGAAATCGGATGTTGAGGCCTTACCTCCAGGCTAGTG +AGGCCACACAAGATGGATCCTCTGGACCCGCCCAAGTGTCCACCTAAACATGAGTTACCA +ACTAACAATGTTTTGTTTAGCATGCAAAGGGAGTGGTCTGGAATCTGGCCTTGCCCTGAC +ATATTCTCCTTGGGCCTTTTTAAAAAAATAATTTGTGTTAATCTGTAGTTAAAAATTATA +ATAAGGACCTGACAAACACTACCTCAGTCAGATGATCAAGGTACACATAAATAGTGAAAG +TCATGTTGATAGCATGCACCCTTCATATGATATGGCTAGAATGGCCCTGCACTTCTGTGA +TCTTCCTCCCCTAGACTCATCAGCTCGATCTAATCATAACAAAAGCATCAGATAAGTCCC +CGCCCAGGGACATTCTACATAACCATTTCCCTTCCCAGTTATATTTTTCTCCACAATACT +TTCCACCATCTAACATTCTATCTTTCAAAATGGGCAAGTATTTTAGCCTGGTTTGTTCAT +TGTTTTATCTGCAACTCAAATACAGTTCCTGAAATAAAATATCTGCCTAATAAATATTTA +ATGAATGAATGAATATAGCATTGCCTTATCCGTTTAATTGCCACATGGTATTTCATTGTG +TGAACATAATATCGTTTATTTACCCAGACTACTACTCATAGGCATTTAGATTATTTCCGG +TCTTTTGCTATTGCTAACAGCCTTTGCAATGAACATCCTTGTATACAGACATTTGCATAT +ATGAGGGTGTGTCTTTAGGATCTACTTCTAGAATTGAAATTGCCAACTCCAAGTATATGT +TTCCAATTGTGATAGATATTACACATTACCCTCCATCTTAGAGGTGGTGTTAATTTAGAT +TCCTGCCAGCAAAATTTAAGAGTGTTTGTTTCCCCATATCCTCAACTGCCTAACAGAATC +AGTGAAAAATGGTATGACAGTGTAATTTTTGAGTGAGGTTGAGTATCTTTTCCTATGCTT +TAAGAGCAATTTATGTTTCCTTTTTATGTGAACTGTCTGTTAATATATTTTTTCAATTTT +TCTATTGGGTTATTTGTCTTTTCATTAATGCATATACCTGTTACATATTTATACCAAGTA +TGTATTAAATACTAACATATTGATGAAACAGAGCAAAAAGCCTAGAAATAGATCCAAATA +ACAGAAGAGTTAGTATGTGATACAGGAAGCCTATAAAATCAGTGAGCAAAAGACCATCCA +ATTAATAACGTTAGGGTAAATGGGTCTCCATTTAGAAAAAAATAATGTGGGTCTACACCT +CACATTTTATACCTAAACAATTCCAGTGGGATAAGAAAATGAAATCATAAAAAATTACTA +GGAAAAAGATGAGAAAATTGTTCATAAAACTGAAGTGTGGAAGATCCTTTATGCCTTACA +CTGCCCTGAGTGATCTCATTCATACCCATGGCTTCAATTGTCATGAATCCCAAATTCATT +CCTCTGTCAGAACTCTCTTCTGAGCTTCAGACCCACATACTCAGCTGCCTACTGGACACC +TCTACTTGAATATCACAAACTCAACTCAAAAGCAAACCTGTCAAATTTAATTACTAGTAG +CCCTACCCCAAACAATCTTCCTGCTCAGTGAATGACACCCATCCCTCCAGGTGCACAGAC +CAGGAACCTAGAAGTCACTCTGATTGCATCCCTCTCCCTCACAACCTCTACCTCCCTTTA +TTCATCCATTGCTATGTCTCTCAAATGTACCTCCCAAATATCTCTTGAACGCGTTCTTTT +CTATCTCTATTGCCACCACCCTAGTTCAAACTCCCATCATCTCATGACTGAAGTTCTGTG +CCCTCTTGCCAGTGAACACTGTAGAATCAATCTAAACATGGTGCCACCCTGCTTAAAAAC +CTTCAAAGGCTCACATCACTTCTCAGATGAAGAGATTGGGGAGACGTTGGTAATAGGACA +CAAAATTTCAGTTAGGCAGGAGGAAAAAGTTCTATTGAAGAACTCTATTGTACAATATGG +TGACTATAGTTAATAACAACATATTATACACTTGAAAATCACTAAGAGAGTCCATTTTAA +GTGTTCTCATGACCAAAAAATGATAAGTATATGAGGTAATGCATATGTGAATTAGCTTGA +CTGAGGCATTCTACATGTATACATATTTCGAAACATCATGTTGTACATCATAAATGCATA +CACTTTTTAGTTGTCAATTTAATTAATATTTTTTAAACCTACTCTGGCCTTTTTTTCCTT +TTTTGAGACGGGTGGTCTCTGTCCCCCATGCTAGAGTGCAGTGCGCAATCATGGCTCACT +GCAGCCTCCACCTCCCAGTCTCAGGCGATTCTCCAGTCTCAGCCTCCCAAGTAGCTGGGA +CCACAAGCATGAGCCACCATGCCCCGCTATTTGTTTTTGTATTTTTTGTAGAGATGGGAT +CTCGCCACATGGCCCAGTCTGGTGTCCAACTCCTGAGCTCCAGTGATCCACCTGCCTCAG +CTTCCCAAACTGCTGGGATTACAGGCGTGAGCCACTGTGCCTGGTCCACTCTGGTCTTTA +CTCAAGTCCCTGGCTTTCTCTCAGTCTCTTAAACTTATGTGCTTAGTAAGATGAGGACTG +AAAAATGTCCACAGAACATAGTGACATGGAGATACTGAGAACCTCAACGACATCTCCATT +AGCCACTTCCTCTGTGCCATTCCAGTCCTCTGGGCCCCACTGTGGCAAGCAGTCCTACCA +TGGCAAACATGAAAGCTGATGTGCCTTGTCTTAGACCCACACCATATCTCTCTGAATTCC +TGTCCCAGGGCTTCTCTGGAGGTACAGCCTGGGAAACTCACGGGAATAGACACAGGGCCT +TTGCACATGCTGCTCCCTTTTCCTGAAAAATTCCTTTGACATCTTGGTTGTGCCTTACAC +ATGCCTACTCAACCTTAGGATTGCAGTTCAGGTTTCACTCCTTTTTTTTTTTTCTTTTTG +AGACGGAGTTTCACTCTTGTTGCCCAGGCTGGAGTGCAATGGTGTGATCCTGGCTCACCA +CAACCTCTGCCTCCTGGGTTCAAGTGATTCTCCTGCCTCAACCTCCTGAGTAGCTGGGAT +TATAGTCATGCACCACCACGCCCAGCTAATTTTGTATTTTTAGTAGAGACAGTGTTTCTC +TATGTTGGCCAGGCTGGTCTCGAACTCCCGACCTCAGGTGATCGGCCCGCCTCGGCCTAG +GTTCCACTTCTTTATGGAAATCTTCCCCAGTTGCCTTGACTAGGCCAAAGTCCCCTCTTC +TTAGGCTCTTACAGTGTCATGCACTTCTTTTTTATCACAGTGTAAACCTTGTAATGTTGT +GTTTAAGTCATATCTGTTGTACCCATGAGACTGGGAGCCAATTCATATATTGTGAGTGTA +ATCGAACAGACTTCCCAGGCCACCCACTAGCTAATCAAGGCAGGGATGAGTCCGGAAAGT +GACTTTGAAATCTAGCAATGTTGGAACTTGGAAATCACACAGGCTGAGATCTGCTCAGGT +GCCTGAACAAATATAGCATTGCCTGTGGCGTCTCCCTCAAAGTGCCTTGCATGTCTGAGC +CCCGTTGCCCCTTCCTTTGGTGTGCCTGTGTCTCCCGGTACAGATGTGAAGCCTGGAGAC +CTGTGGCTGCCTCTGCAGGAGCTCCATGTTTTCAAGCCATAAATCATCTTAGAATTCATA +GCATCTAGATATATTAGTTTTCTATTACTGCAGAACAAATCGCTCCCAAATGTAGAGGCT +TCAAAGAATGCCCATTGATTGGCCTTAATTTCTGTAAGTTAGAATCTGGGCAGGTTTGCC +TGAGTTCTCCACTCCAAGTCTCATAAAGCCAAGCTGGGCTGTCATCTGGAGGCTCTGAGT +AAAAATTTGTTTCCAGGTTCATCCAGATTGTCAGGTGATTTCAGTTCCTTGCAGTTGTTG +TTCGACTCACTACCCCACCACCACCCCGAAAACCTCATTTCCTTGCTAGCTGCCTGCAGA +GAGCCACTCTCAGCTTCCACAGGCTGCTTGCATTCCTTGTTGTGGGGCCGCTACCTCCTC +AAGCCAGAAATAGGGCATCCAGTTCTTCTCATGCATCCTACCCCTCTGACTTTTCCTTCT +GCCGATAACCAGAAAAAACGTTCCGCCTTCAAACGCTCGTATGATTAGACTAAGCCCATC +CAGATAAATTCCCATATGCCATATACTATAATGTCATCACAGCAGTAATACCCGGGACAA +AATTCATGGGGGTCATCTTAAAATTCTGCCTATCACACCAGGTATAGTAGAGGCTTGTTT +TAGTGCAAGTTAAACATTAAGCAGCAACATCACGATAGTGCTGCATTTGAAAATAACTAC +TAGCAACTGAACATGTCTGGGAGTTCTGCTCCACTTTAATTTCCATCTCAAAAGGAGCTG +GGTTTTCCTTGGCTGTTACAAATGGGCAATAATGATTGAGCTTAAGAATAATCAATGTCC +ACATAAAAATCTTTTATAACATAGTGAGAGTGTGACATATAAAGGTGTTAGTTCACCGGC +CCTAAATTTTAGGAGAATTTTTAAAAAGGCACTTATCTGGTTTAATCCATAATAAAGACA +TGAGTTGGGCTTTAGTGAAAAATCTAGGCTGGTTTCTGTGTTCAGTGAAAGAAGATTTGA +GAGTTCTCTTAATTACAACCCTTGATCAAACCTACCACATTAATCTGTTTATTGCATTGT +ATGGTTACCAAAAGTGATATATTCAGCCCTCTATTTATTAAGAAACAGTTACAGAAAGTG +AGGCACTCTCCTGTGTTACTGAGGGTGCATAAAAATATAAAGCACCATGTGTCTTCCCTA +GAGAAGTTTCAAAACTAGCAAGCAAATAGCTATTAATGCTAATGTTTGTGTGATAGGGAA +CATATGAGTAGTAATTATTCCACAAACAATTTTTTGAGTGCTGTTTACATTTGAGGCACA +GTTCAGGCACGAGGATTTCAAAAGGAGATTGTGTAGCATGATGGCTTGTTAAAAATATGA +TTTTGGAATCAGATTTGCTCAAGTCCCAGTGCTACAGCATACCATCCTTCAAAAAGGTAC +TTAAGTCTCTGAGTTTGTTTTCTCATCTGCAAAATATAAATAATAAGAGGACCTACTGCG +TCATGTTCTTGTGAGCATTAATGTGGGTGATGAAATGTTTATGAAGCACTTAGCACAATA +CCTGACATTTTGTTTGTTATTATTATCAACATAAAGTGCCCACTTTCCAGTCATGCAAGA +AGAAAACATAATATATGTCACCATAGAAGTATAGAACAATTGTGGGAAATACCAGTAAGA +GAGATATAGCTGTATAAATAAGGTAAAGATGACTGCCTAGAAGATCTAGGATGATACCAT +ATTAGAAGTTGCATCTGAACTCTCCTTGGGGACTGGCCAAAGTTTCATCAAGTGTCATGT +CAGTAGGTTGGTGCTATAAATATATAGCTTGCAAAGCTATAGACTTACTATAAACCATAG +CTGTGGTCCAGCTTAGACTCATTATGGTGGTGGAGTATCTTGATTAATGGCCTCTGCAGA +AGCTTCCCAGGTCTTCTCATCATCATAATCTCAGATAGCTTCATCTTCAACTTCCTTTTT +TTTGTTGTTTTTGAGACAGGGTCTCACTCTGTCATCCAGGATGGAGTGCAGTGGCACAAT +CATGGCTCACTGCAGCCTCGACCTCAGGAGCTCAAGCCATCCTCCCACTTCAGCCTCCCG +AGTAGTTGGGACTACAGGCATGCACCACTACGCCCGGCTAATTTTTTCATTTTTTTGTAG +AGTCAGGGTCTCCCTATGCTGCCCAGTCTGGTCTCAAACTCCTGGGCTCAAACCATCTTT +CCACCTCGGCCTCCCAAAATGTTGGGATTACAGGTGTGAGCCACCACACACAGCCCATCT +TCAACTTCTTTTAGCACCATGAAGCTGAACATAGTAAAAAAGTAAAATCATTCTGGACCT +AATCTGATGCAATTTATTTAATTGTTAAGTGAATGCACACATCAAAATTCATACAAGTAT +GGGGCAGCGCTGCTAATTTATTTACAAAACACCTGGCAAATACTGCTACTCTAATACTGT +GCTTCCACTTTTGATTTTCCTTAGGAAAACATGTTCCTTCAGTCGTCAATGCTGACCTGC +ATTTTCCTGCTAATATCTGGTTCCTGTGAGTTATGCGCCGAAGAAAATTTTTCTAGAAGC +TATCCTTGTGATGAGAAAAAGCAAAATGACTCAGTTATTGCAGAGTGCAGCAATCGTCGA +CTACAGGAAGTTCCCCAAACGGTGGGCAAATATGTGACAGAACTAGACCTGTCTGATAAT +TTCATCACACACATAACGAATGAATCATTTCAAGGGCTGCAAAATCTCACTAAAATAAAT +CTAAACCACAACCCCAATGTACAGCACCAGAACGGAAATCCCGGTATACAATCAAATGGC +TTGAATATCACAGACGGGGCATTCCTCAACCTAAAAAACCTAAGGGAGTTACTGCTTGAA +GACAACCAGTTACCCCAAATACCCTCTGGTTTGCCAGAGTCTTTGACAGAACTTAGTCTA +ATTCAAAACAATATATACAACATAACTAAAGAGGGCATTTCAAGACTTATAAACTTGAAA +AATCTCTATTTGGCCTGGAACTGCTATTTTAACAAAGTTTGCGAGAAAACTAACATAGAA +GATGGAGTATTTGAAACGCTGACAAATTTGGAGTTGCTATCACTATCTTTCAATTCTCTT +TCACACGTGCCACCCAAACTGCCAAGCTCCCTACGCAAACTTTTTCTGAGCAACACCCAG +ATCAAATACATTAGTGAAGAAGATTTCAAGGGATTGATAAATTTAACATTACTAGATTTA +AGCGGGAACTGTCCGAGGTGCTTCAATGCCCCATTTCCATGCGTGCCTTGTGATGGTGGT +GCTTCAATTAATATAGATCGTTTTGCTTTTCAAAACTTGACCCAACTTCGATACCTAAAC +CTCTCTAGCACTTCCCTCAGGAAGATTAATGCTGCCTGGTTTAAAAATATGCCTCATCTG +AAGGTGCTGGATCTTGAATTCAACTATTTAGTGGGAGAAATAGCCTCTGGGGCATTTTTA +ACGATGCTGCCCCGCTTAGAAATACTTGACTTGTCTTTTAACTATATAAAGGGGAGTTAT +CCACAGCATATTAATATTTCCAGAAACTTCTCTAAACTTTTGTCTCTACGGGCATTGCAT +TTAAGAGGTTATGTGTTCCAGGAACTCAGAGAAGATGATTTCCAGCCCCTGATGCAGCTT +CCAAACTTATCGACTATCAACTTGGGTATTAATTTTATTAAGCAAATCGATTTCAAACTT +TTCCAAAATTTCTCCAATCTGGAAATTATTTACTTGTCAGAAAACAGAATATCACCGTTG +GTAAAAGATACCCGGCAGAGTTATGCAAATAGTTCCTCTTTTCAACGTCATATCCGGAAA +CGACGCTCAACAGATTTTGAGTTTGACCCACATTCGAACTTTTATCATTTCACCCGTCCT +TTAATAAAGCCACAATGTGCTGCTTATGGAAAAGCCTTAGATTTAAGCCTCAACAGTATT +TTCTTCATTGGGCCAAACCAATTTGAAAATCTTCCTGACATTGCCTGTTTAAATCTGTCT +GCAAATAGCAATGCTCAAGTGTTAAGTGGAACTGAATTTTCAGCCATTCCTCATGTCAAA +TATTTGGATTTGACAAACAATAGACTAGACTTTGATAATGCTAGTGCTCTTACTGAATTG +TCCGACTTGGAAGTTCTAGATCTCAGCTATAATTCACACTATTTCAGAATAGCAGGCGTA +ACACATCATCTAGAATTTATTCAAAATTTCACAAATCTAAAAGTTTTAAACTTGAGCCAC +AACAACATTTATACTTTAACAGATAAGTATAACCTGGAAAGCAAGTCCCTGGTAGAATTA +GTTTTCAGTGGCAATCGCCTTGACATTTTGTGGAATGATGATGACAACAGGTATATCTCC +ATTTTCAAAGGTCTCAAGAATCTGACACGTCTGGATTTATCCCTTAATAGGCTGAAGCAC +ATCCCAAATGAAGCATTCCTTAATTTGCCAGCGAGTCTCACTGAACTACATATAAATGAT +AATATGTTAAAGTTTTTTAACTGGACATTACTCCAGCAGTTTCCTCGTCTCGAGTTGCTT +GACTTACGTGGAAACAAACTACTCTTTTTAACTGATAGCCTATCTGACTTTACATCTTCC +CTTCGGACACTGCTGCTGAGTCATAACAGGATTTCCCACCTACCCTCTGGCTTTCTTTCT +GAAGTCAGTAGTCTGAAGCACCTCGATTTAAGTTCCAATCTGCTAAAAACAATCAACAAA +TCCGCACTTGAAACTAAGACCACCACCAAATTATCTATGTTGGAACTACACGGAAACCCC +TTTGAATGCACCTGTGACATTGGAGATTTCCGAAGATGGATGGATGAACATCTGAATGTC +AAAATTCCCAGACTGGTAGATGTCATTTGTGCCAGTCCTGGGGATCAAAGAGGGAAGAGT +ATTGTGAGTCTGGAGCTAACAACTTGTGTTTCAGATGTCACTGCAGTGATATTATTTTTC +TTCACGTTCTTTATCACCACCATGGTTATGTTGGCTGCCCTGGCTCACCATTTGTTTTAC +TGGGATGTTTGGTTTATATATAATGTGTGTTTAGCTAAGGTAAAAGGCTACAGGTCTCTT +TCCACATCCCAAACTTTCTATGATGCTTACATTTCTTATGACACCAAAGATGCCTCTGTT +ACTGACTGGGTGATAAATGAGCTGCGCTACCACCTTGAAGAGAGCCGAGACAAAAACGTT +CTCCTTTGTCTAGAGGAGAGGGATTGGGATCCGGGATTGGCCATCATCGACAACCTCATG +CAGAGCATCAACCAAAGCAAGAAAACAGTATTTGTTTTAACCAAAAAATATGCAAAAAGC +TGGAACTTTAAAACAGCTTTTTACTTGGCTTTGCAGAGGCTAATGGATGAGAACATGGAT +GTGATTATATTTATCCTGCTGGAGCCAGTGTTACAGCATTCTCAGTATTTGAGGCTACGG +CAGCGGATCTGTAAGAGCTCCATCCTCCAGTGGCCTGACAACCCGAAGGCAGAAGGCTTG +TTTTGGCAAACTCTGAGAAATGTGGTCTTGACTGAAAATGATTCACGGTATAACAATATG +TATGTCGATTCCATTAAGCAATACTAACTGACGTTAAGTCATGATTTCGCGCCATAATAA +AGATGCAAAGGAATGACATTTCTGTATTAGTTATCTATTGCTATGTAACAAATTATCCCA +AAACTTAGTGGTTTAAAACAACACATTTGCTGGCCCACAGTTTTTGAGGGTCAGGAGTCC +AGGCCCAGCATAACTGGGTCCTCTGCTCAGGGTGTCTCAGAGGCTGCAATGTAGGTGTTC +ACCAGAGACATAGGCATCACTGGGGTCACACTCATGTGGTTGTTTTCTGGATTCAATTCC +TCCTGGGCTATTGGCCAAAGGCTATACTCATGTAAGCCATGCGAGCCTCTCCCACAAGGC +AGCTTGCTTCATCAGAGCTAGCAAAAAAGAGAGGTTGCTAGCAAGATGAAGTCACAATCT +TTTGTAATCGAATCAAAAAAGTGATATCTCATCACTTTGGCCATATTCTATTTGTTAGAA +GTAAACCACAGGTCCCACCAGCTCCATGGGAGTGACCACCTCAGTCCAGGGAAAACAGCT +GAAGACCAAGATGGTGAGCTCTGATTGCTTCAGTTGGTCATCAACTATTTTCCCTTGACT +GCTGTCCTGGGATGGCCTGCTATCTTGATGATAGATTGTGAATATCAGGAGGCAGGGATC +ACTGTGGACCATCTTAGCAGTTGACCTAACACATCTTCTTTTCAATATCTAAGAACTTTT +GCCACTGTGACTAATGGTCCTAATATTAAGCTGTTGTTTATATTTATCATATATCTATGG +CTACATGGTTATATTATGCTGTGGTTGCGTTCGGTTTTATTTACAGTTGCTTTTACAAAT +ATTTGCTGTAACATTTGACTTCTAAGGTTTAGATGCCATTTAAGAACTGAGATGGATAGC +TTTTAAAGCATCTTTTACTTCTTACCATTTTTTAAAAGTATGCAGCTAAATTCGAAGCTT +TTGGTCTATATTGTTAATTGCCATTGCTGTAAATCTTAAAATGAATGAATAAAAATGTTT +CATTTTACAAGAGGAGTGTATGATAAATAT diff --git a/test/csq/ENST00000218032/ENST00000218032.fa.fai b/test/csq/ENST00000218032/ENST00000218032.fa.fai new file mode 100644 index 0000000..13d3207 --- /dev/null +++ b/test/csq/ENST00000218032/ENST00000218032.fa.fai @@ -0,0 +1 @@ +X 16590 23 60 61 diff --git a/test/csq/ENST00000218032/ENST00000218032.gff b/test/csq/ENST00000218032/ENST00000218032.gff new file mode 100644 index 0000000..dd5a558 --- /dev/null +++ b/test/csq/ENST00000218032/ENST00000218032.gff @@ -0,0 +1,8 @@ +X ensembl_havana gene 21 16570 . + . ID=gene:ENSG00000101916;Name=TLR8;biotype=protein_coding;description=toll-like receptor 8 [Source:HGNC Symbol%3BAcc:15632];gene_id=ENSG00000101916;logic_name=ensembl_havana_gene;version=11 +X ensembl_havana transcript 21 16570 . + . ID=transcript:ENST00000218032;Parent=gene:ENSG00000101916;Name=TLR8-002;biotype=protein_coding;ccdsid=CCDS14152.1;havana_transcript=OTTHUMT00000055784;havana_version=2;tag=basic;transcript_id=ENST00000218032;version=6 +X ensembl_havana five_prime_UTR 21 107 . + . Parent=transcript:ENST00000218032 +X ensembl_havana exon 21 110 . + . Parent=transcript:ENST00000218032;Name=ENSE00001907173;constitutive=0;ensembl_end_phase=0;ensembl_phase=-1;exon_id=ENSE00001907173;rank=1;version=1 +X ensembl_havana CDS 108 110 . + 0 ID=CDS:ENSP00000218032;Parent=transcript:ENST00000218032;protein_id=ENSP00000218032 +X ensembl_havana CDS 12445 15567 . + 0 ID=CDS:ENSP00000218032;Parent=transcript:ENST00000218032;protein_id=ENSP00000218032 +X ensembl_havana exon 12445 16570 . + . Parent=transcript:ENST00000218032;Name=ENSE00001130430;constitutive=0;ensembl_end_phase=-1;ensembl_phase=0;exon_id=ENSE00001130430;rank=2;version=6 +X ensembl_havana three_prime_UTR 15568 16570 . + . Parent=transcript:ENST00000218032 diff --git a/test/csq/ENST00000218032/start-lost.txt b/test/csq/ENST00000218032/start-lost.txt new file mode 100644 index 0000000..61b5341 --- /dev/null +++ b/test/csq/ENST00000218032/start-lost.txt @@ -0,0 +1,3 @@ +108 A G start_lost&splice_region|TLR8|ENST00000218032|protein_coding|+|1M>1V|108A>G +108 A G start_lost&splice_region|TLR8|ENST00000218032|protein_coding|+|1M>1V|108A>G + diff --git a/test/csq/ENST00000218032/start-lost.txt-l b/test/csq/ENST00000218032/start-lost.txt-l new file mode 100644 index 0000000..61b5341 --- /dev/null +++ b/test/csq/ENST00000218032/start-lost.txt-l @@ -0,0 +1,3 @@ +108 A G start_lost&splice_region|TLR8|ENST00000218032|protein_coding|+|1M>1V|108A>G +108 A G start_lost&splice_region|TLR8|ENST00000218032|protein_coding|+|1M>1V|108A>G + diff --git a/test/csq/ENST00000218032/start-lost.vcf b/test/csq/ENST00000218032/start-lost.vcf new file mode 100644 index 0000000..5ebcedc --- /dev/null +++ b/test/csq/ENST00000218032/start-lost.vcf @@ -0,0 +1,6 @@ +##fileformat=VCFv4.2 +##contig= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO +X 108 . A G . . EXP=start_lost&splice_region|TLR8|ENST00000218032|protein_coding|+|1M>1V|108A>G;type=ENST00000218032:12924826-A-G diff --git a/test/csq/ENST00000227471/ENST00000227471.fa b/test/csq/ENST00000227471/ENST00000227471.fa new file mode 100644 index 0000000..b1e8bd5 --- /dev/null +++ b/test/csq/ENST00000227471/ENST00000227471.fa @@ -0,0 +1,233 @@ +>11 11:67758555-67772472 +GCCTGGGACTCCCCAGTCAGGACAGTACAAAATCTCTTTATTGCTCATTTTCTGTAAAAA +ATCGTGGCTCTCGGCGGACCCTGGGGATAGGAGGTGCAAAGTGCGCTCACACGCGGCCCG +GGTCCGCGGCCGAGAGCTGTGGGGATCTGGAGCGGGCCGGGTCGCAAGAAGACCCTGACC +GTGCTCCGGCGCTGGGGCGCGTGCTAAGGGCCCGCGGGGTTTCAGCTGTATTTTCGAACC +CCTGTGCTTGGCCGAGGGGTTCCCAAGGCTCCACTCCGCCTTGGAGGGGGCTGCGGAAGC +CCGGAGGTGACCTGGGCTCTGGGAGGGGCGTCCCCAACGTGGGGGAGGGGAGACAGGGGC +CTTTGAAGACAGCGCGGGACTCGGAGGGGGTCCCCCCGACCTCAGACGTGGTAAACTGAG +GCCGGCGAGGAGGGAGGCTGAGTCCGGGGACCAGGCGGCCCCTCACTGCTCCTCCGGCCC +GTCTCCCCCCTGCGCCTGTTCGTACGGGCAGGGCCGGCGGCCGAGTCCAGCGGGCTCGGG +GCCAGGCCTGGGCCCTGCGGGCGGCGCCTCCTCCTCCGCGCCGTCCCCATGCTCGCCCTC +CGCGTCGCTCTCGTCCGAGTTGTCCTCCTCCAAGTAGCGGTAACCGCGCACCTTGTGCTG +GGGCCGCGGGATGCGGGGCTGGCGCGGGGCCACGCCCCGGCGCAGCTTCTGCTCCATCCG +CAGGTAGGAGACCGCGGCCGCCACCAGCGTCACCAGCAGCACCGCCAGCTTAGCCTGGGC +GTAAGGAGAGGGATGCCAGGGACCCGCGGCCGCCTCGCCCCGCACCTTCCCCGCCTATGC +CCCTCGCTGAGATAGGCCCTTCCCTCCTCCGGGAGCCTCCCGGGCCACGCGGCCCTCAAC +TTCTCCAGCCCCTCCACCCATGCTTCCTGGACCGCCTCCTGCAGGCGAGGCTCACATCCA +GCACTGTCCCTTACAGTCGCCACGCCCCTGGCGACCTCAGTGTCCCACACTGTAAGGGGA +CAATGCAAATCCCTTTGCCTCATAGGGTGCATGCGCCAGTGTTGATAAAGTGCTGGCCAC +AGGCCCTGCCTTCCCAGGGCTCACAACACTGTGTCCCTGACACACCCGTGGGCTGTAGTG +ATGCTTTTCATGGGGTTTTGACTATAACCCGCAGTCAGGAATGATTTCACACCATAGCCC +AGTACATACACACATATCTGTATGCATACTTCCTGCTCTTTTCTTTTTTCCAGACACGGT +CGCTCCGTTTCCCCACCGCGCCCCCTCCCTCCCTTCCCCCACCCACTGCTGGAGCGCAGT +GGCACGCTCACTTCAGCCTCAATCTTCCAGGCTCAAGCCATCCTCCCACTTCAGTCTCCC +AAGTAGCTGGAACTACAGGCACACGCCACTACGCCCAGCTATTTTTTAAATTTTTTGTAG +AGACAGGGTCTCCTATGTTGCCCAGGCTGGTCTTGAACTCCTGGCCTCAAGCAATCCTCC +TGCCTCAGCCTCCCAAAGTGTTGGGATTACAGGCGTGAGCCACCATGCCCAGCCCACTCA +CTGCTTTTCTTTTTTTTTTTTCCTTTTTTTTTTTTTTGGAAGACAGAGTCTCGCTCTGTC +CTCCAGGCTGAAGTGCGGTGGCGCGATCTTGGCTCACTGCAACCTCCATCTCCCAGGTTC +AAGCCATTCTTGTGCCTCAGCCTCCAGAGTAGCTGGGATCACAGGGACGTGCCACCATGC +CCAGCTAATTTTTGTGTTTTTAGTAGAGACAGAGTTTCACAGCCTGTTACCCAGGCTGGT +CTCGAACTCCAGATCTCAGAACCCCCACCTCAGCGTCTCAAAATGCTGGGATTACAGGCG +TGAGCCACTACTGCCAGCCCACTCCCTGCTATTTTTAGTTCTATTTTTATTTTTATTTTG +AGACGGAGTTTCGCTCTTGTTGCTTAGGCTGGATGGAGTGCCAACGCCCCGTCTCGGCTA +ACTGCAACCTCCGCCTCCCAGTTCAAGTGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGT +GATTACAGGCACCTGCCACCACGCCCGGCTAATTTTTGTATTTTTAGTAGAGACGAGGTT +TCACCATGTCGGTCAGGCTGGTCTCAAACTCCCTACCTCAGGCAATCCACTCGCCTCGGC +CTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCGCCCGGCCTTTAGTTCTATTTTT +AAAAAATGTTTAGCAACTGGGACTTGCTAGACCGAGCCACCATTTTTTGTGAGCAGAGCA +TGAGGAGCCTGCTCCCCTTCAGGCCATGAAGAGAGACAGACCCAACATCTGGAGAACAAG +GTACCAAACAGCCCACAGGATGGCTGTGATGCACCCACAAATCCCCTCAGAGATGGGCAA +ACTGAGACTGGCTGGAGGTGGGCCAGTAAGTGGGGTGCTGAGTTGGGGGCCACCCAGTGG +GCTGCAGGAATGGGGCCTTGGCCCAGAGACTGGCTTGGGAAGGGGTGGCATTTAGGAAGC +TGTGAAGCCAGGGCAGGGGCTAAGGAAGTACCTGTCATTGGGCATGGGGCCCCCAACCCT +GCCCAGTCTCACCTTCATGTGCAGGCTCGAGCCCAGGTACACGGTGAAGATGGCCACAGC +CTGCCACCAGTGGTAGATGGTGAAGATGAAGTCCTGTCTCTCCTTGTCTTCGTACAAGAT +TCCCAGGAGTGCTGCAGGCAGGCAGTACAGGGCAGGCAGGGGAGAGGTGTCACCTGGGGC +CTGGGGCTACCGAGCTACCATCTACGAACTTTACTAAGCCCTGTATGGGTCCCAGCCCCG +GACCAGAGAGCGCCTAGAAAGTGCTGTGAGGCGGTCCTGGCCTGCCCCCTGGTGGAGACC +CTGGTCACCACACTGCTCACACGCTAAGCAGAAGTAGGAGCAGGTGCCTCGGGCTGTGTG +GATGCAGGTGTTCCCGCTCCGCACCACATGCGTGGCCTCAAAAGAAGAAAGCTCTGTGCT +TAGTCATGTCCTGTCCCCAACCCAGGTGTGCAGTGCCAAGCTTGCAGGCGCTGTTTCTCC +TCCTCAGCCAGGACTAGAGAGATCGAACTGTTTGCAGCTGCCAACTCTGCAAATCAAACC +TGAAGCTAAGCATGGAGAGGGGGGATTCCTTTCCAGTGAGTCCTCCCAGGGTGGGCAACA +AGAGTAATGGATTGGGAGTCAGAAGATGCACGCTCGTTCTCAGGGCTGTAATGTTGGCTC +TGTGGGTGATTTGGGTACTTAACTCCCCAGAGCTGCTTTTCCCAATGGTGAGATGAGCTT +ATGCCTATTGTGTGCTGTGTTCTGAAGTTCTAAAGTGAGAAAGTGGGCATGGCACCTGCC +AAATCATAGGGGCCACTATTAACACCTTCACCAGGCACTCAGGATATGAACACTCCTGTT +TTGGGGCCCTGCAGGGTGACTTTACCCCCACAGTGCTGCTATGAAGAGACAAGGACCCCC +CGGGGTTCACCGGAGGAGATGGGATATGGAGCTGGGCAGAGGGGATGCCAGGACCAGACA +GGGCACAACATGGGTTCAAGATACCCAGGCTGGACTCTGCCCAGAATTGGCTATCCTTGG +GCAAAACGGCCAAGAGACTGTGGTGCAGTATGAGGCTCCAGCCCCTGCTACAGACAGAGA +CACAGAGCCAGCCTCCGCCCTGCCAGCAGCAGGCATGACCTCGGCTACTCCACACCCCCA +AGGATGACGTTCAAAACTGTTCACAGCTTCGGCCCATCAGAACAGACACTGACATGGATG +CCCGGCAGGACTGCCCATGTGTGCTAGCTGTGTTTCACTGCGTGTGCCCATCTGTGGTCA +GGGAGCATCCTGGAGCTGAACATGGGCCCACCCGCTGCCTTCTGCAAACAGGGCCCTGTT +CCCCAGCAGCCCAGACCTGGGGCCTGGACTCTGGTACTGAGCAGACTGGGTTGGGGCTGC +AGGCCTGCTCCTCTCTATACAAAGGCCCATGTCTGTATCTATGCCATGGGTGTACAACAG +GCCACTTGCTCCTACCACATGCTCCGTGAAGCAGAGACCAAAACATCTGCTCCAAGTGTC +ATGAAAACTATGCCAGGGTAAGCCCTGTCCCCTGGTATGAAAAGGGAGAATCCCTGATGT +GTTTTTCACACTGTCCCTAAGGGGTGTCCACAGAGCCCCACACCTGCCCCATGTAGCCAC +GAGACTTCACACTGACCCTCCAGTGTTGATGGGGCCCTGTGCCCGCTCTGGGGTATTAAC +AGAATGTCCATGGCATGGAACCCCCATACCTGTCTCCAGGGTGTCCACACCCTACCCATC +TGTCCCCAGTGTGTCCATAAGACTTCCCTTCCACCCCCGGAGTGTCCACAGGAAGCCCCA +CCTGCCTCTGCCATGTCCACAGGACCCTATGTGACCATGGGACCCCATATCTGTCCCTGG +GATGTCTATGTCTCGCCAACCACCCACAGATAGCCATAAAGCCCCCTGCCCCGCCCCCCC +CCCCCCAGTGCCCACAGCTATACTCACTGCTGAGTCCAGTCTTGTTCAGGGCACTGCCCA +CACCCCAAAGGGCAGCTGCCACATAGAGGATCCAGCTGTGTTGCAGGACCCGAGGCACAG +GGGCCCAGAAAAAGAGGATGAAGGTGAGCAGCAGGTGCACCCCTGCTCCGGCCACCAGGG +GCACCGGGCGTGGCAGCCACAGGCCCAGCAGGCCCAGGAGTGAGGCGGCTGAGGCGCCCA +GGCTGTAAGCCACGAGGAGGTAAGCCAGCCGCTCCAGCCCCACCGAGCACACGCCATAGC +CCTGCGGGGGGACAAGGGGTGAGTGTTGAAGTCTGGAACAGCCCAGACCACAGTCTCAGC +CCTCCCCGCATCGCGGGGGTGCCTCACCCCCCTGCGATGGGGGTCCTAAGAGCCAGGGGG +GAAGAGGGTCTGGCTCTTACTCCCCGCATCGTGGGGGGTGCCTCACCCCCCTGCGATGGG +GGTCCTAAGAGTCGGGGGGAAAAGAGGGGTTGGCTCTTACTCCCCGCATCGCGGGGGGGT +GCCTTACCCCCCTGCGATGGGGGTCCTAAGAGCCAGGGTGGGGAGAGGGGCCCCCCGCGA +TACGGGGAGTAAGAGCCAGGTGGGGAGAAGGGCTGGCTCTTACTCCCCACAAGAGGTGTT +CCTTAGGCCACACCCTGCCCTCCCTGGACTGCCTGACCTCGCTCCAAGGCTCAGGGGAAG +GTTCTGAGGGCAGGTGTGAAAATGCTTGGAATGTCCCTAGACACCGTGGGCTGTACCCCA +CAAGGAACTAAACACTCTGTGGGTGCTATCCCATTTCGATTCAGAGAAGTTAAAATAACT +TGCCCAAGGTAAAGGGGGGACGGGGGTAAGAGAGGGAAGAGAAAGCAGGAGGGGGATATT +TGGGATATACATGTACACACTTACATATGTAATTAAAAATTATTCTTTGTTTACTTGAAT +TCAAATTTACCTGGCTATCTTGTCTTTTGTCGGGCAATCCTTTGCAGGCTGTACTTACCA +AGGCGATACCAGTGCAGGCAAAGAGCACCTCGAAGCCGCTGTAGATAAAGAAAGGCACGA +GGTGGCGCAGGCGGTAGTCACGCACGTGCTTGAAGGGCAGCTGGAAGATGTTGCCCCAGC +CCACGCTGCGCAGATCGATCTCCTCCGTGGGCCGGTAAGCGGCTCCGCACAAACCCAGCA +CCTGCGAACCCATTACTTGAAGGGGCGGCCAGCCAGGCCCAGGCCTGGCCTCCAGGCTTC +AGCCCCGCCCTTCAGATGCACCACGTGCCTGGGCCTTGCCCCAGCTCGGCCCCGCCTCCC +AAACCAGGGCCCCGCCCCTGAGACACTCCCACAGACCCAGGTCTTGCCTTATCCCAGCTC +AAGGCCCCGCCTCTCAGCACAAAGCCACGCCACCACACTCCGAAAGACGGTGGTCTTGCC +TCCCAGCCCAAGGCCCCATCCCCTCTCTCTCACATACACACACTTCACAACTCACATTCA +GACAAATCCATAGACTTCAACCTTCCTTCTCAGCCCCGCGCCAGACCTCAGCCCCGCCTT +CCAGGCTAGTCCCCGCCCCTCGGACACACCCACAGACTTCGGCCCCGCGTCCCAGCACTA +GGCCCCGCCTGACACAGCCACGGACTGGGCCTTGCCTCCCAGCTCCATCGCCAGGCTGCA +GCATGCCAACGCCTTAGTTCTGCCGTCCAGTATCACTTCCAGTTTGAGCCACACCTTCCA +GCCCTCACCCTTGGTCCTGTCCCCAACCCCCTCACAGGTCTCAGTCAGTCTTCTAAGATC +TTGTCTCCAGCTCGAAACTGTGGACCAAGCCTGTTCCCTCCTTCCCCTGGCCTCTGGATG +CCCACGCCTGCCTCGGACCACAGGCCTCAGCCCCGCCTCCGAGCCTCATGCCCGCTCTGC +AGCACTCGGCCCTAGCTCCCCAACTCAGATCGCGCTCCCAGGCCTACGGCCTGCCCCGAG +GCCACAACCCGACCCAGGCCATGCCATCCGATCCAGACCCTTTCTCGCAGACTCGGTCCC +CAGAACCACACTCTGCTTCACTGACTGTCCTGCCCCCATCCCGGGCCGCACCAGCAGCAT +GGCCAGGAAGCCACTGCCATGAGCACGCTCTCCACCACAATGAGGTTTCCGCTCCGCGGG +AGCGTCCGCAGAACCGTCTTGTTGAAGCCGCTGAGGATCCCGTGGCTGTTGGTGCCTGGG +AAGGGTGGGGGTGAGGGCACCGTGAGCAGAGAGTAGGGCACACAGTCAATCCAGCCACCA +GGGTGGAGCCACGCAGGCCGCGGAGGAGCGGTGGAGGGCGGGAGAGTGAGAGCAAGGGCA +GAGTTCCTTCAGAGAGCAGTTTGGAGGTTTGGACCACTGGGGCTGGGTTTGGACCACTGG +GGCTGGGTGTTCCCCGGGAAAGGGGCATCTTTCCCCTGCTTCCCACCCTATTTCCCCAAG +GCTCAGTGGACCTCACATTTCCATGCACACCCCCTGCACTGATTGAGCTCTGACTGTTTG +CCTGGCCCCAAGAAAGATCCCACTGGCAGCCTCAGCCCAGATGGTGCCTTCTCCAGGCAG +TCTTCCCCGCCCACCCACTCTCCTGGCTGGGTCAGATGTCCTAACTACTTACTCCTACAG +GGCCCTGTGTCTTGCCCACCAGAGCCGTGGGGCACTGGGCTGCCAGCCCTGAATCCTGTG +AGTGAGGGCCCAGTGTCTGCTGGGGAAGTAAGCAGGCTTTGTGGACTCCTCCCCAACCCC +CAACAAGGACTAACCGCAGCTCTGCACATTGTACAGCGTGTGGTTCAGGTCATACAGGTA +GTGGTTCAGGAAATAAATCATGGGCAGCTGGGCGCAGGCGAAGCTCAGCTGCAGAAACAA +GGGCAGTTGGGACCAGACTCAGGCACAGAGCCAGGCAAGGGACACAGGCATGGTCTGGGG +AGGGGTCCAGGCACAGCCTTGGGGGAACAGGGGCCTTCCCAGTTCTGGGAGTAGTGTGGT +TACAGGGCCGCCCAATGAGGAAGACCTCCTCCTGGCCAGCATTGTGGAAAAGGGCAGATG +AGATCTCTATCTCTATGGATGAGCAAGCTGGGGTGGGCTCAAGAAAGGAAGATGGGCAGC +CTGGGCAACATAGTAAGATCCTATCTCTACAAAAAATAAAAAATTAGCTGGGTGTGGTAG +CACACGCATATGATGCCAGCTACTCAGAAGGCTGAGGTAGGAGGATCACTTGAGCCCAGC +AGTTCAAGGTTGCAGTGAGCTGTGACTGCACTACTGCACTCCAGCCTGGGCAACAGTGCA +AGACCCTGCCCCCAACCCCCACCAAAAAAAAAAGAAAGAAAGAAAAAGAAATGAAGGTGG +GGCAGATACAGTGGTGTGCGCATGTAGTCCCAGCTACTTGGGAGGCCAAGGTGGGAGGAT +CACTGGAGCCCAGGAGTTCAAAGCCATCTGGGCAACATAGTGAGACCAGGCCTCTTAAAA +ATAACAATAATAAAAGAAAGAAAGTGGGACTAGAGGGTTGAGACTGTGGATGGGCTCCAA +TGCGTGGGTCTGCCCCTGCCACCCAACAATGGCCCACGTGGCACTCACATGGAAGAAGCT +GTAGAAGATGGCTTGGAAGACCAGGAGATAGGGCGCGTGGGAGCCCCGCGGAGGCCGCTG +CTTCATCCCCTGCCCATCCTGCTCCTTGTAGTGGGAGTACTCATGGTACTTCTGCGCCAT +CCTGGACCACAAAGGAGAGAAGGCTCTCCCCAGCCCGACCTGTGCCACTCCTGTGTGTCC +TGCACCCAGAGCTAGGAGCAGACCAGCCCCGGTGTGGGGAAACTGAGGCCCAGAGGGCGG +AAGGGGCTTCCTGTGGTCCCCCAGCCAAAGTTGGCAATAAAGTGGAGGCTTGGCCAGGTC +TCCAGCCTCCTGCCCTGCTGCCCACCAGGCTCACCTGGTGATGTAGTTGCCCATGGAAGC +CCAAAGAGGCACGATGGCCATGCCCAGGGCCACAGCCGAGGGCACAAGCGTGTAGTAGCG +CTCCCAGTAGTTGGTGGAGACAAAGAGGGCGTAGATGCCCACAGCGAGGAACATCATCCA +CTTCGTTCCAAAAAACCTGCGGACAGTGGGAGAGATGCTGGCACCACAGGCCTGCTGGAC +CACTGTGGCCTGAAGCCAAACGGGGCCACAACCGCAGGTCCCAGCTCACAGGGCTTTGTG +AGGTAGAGAGAGTCGAGGGCACTGAGATGGAATATCAGATACACAGACTTGCTGAGTGGC +CTCAGGCAAGCTACTGTGCCTCAGTTTTCCCAGCTGTAATATGGGCACGGAGCCCAAACC +ACAGGCCTCTCATCACCACTGTGAGGATGGAGAGTGACCCATGGGTGTAACCAGCCCTCA +TGCGTGTTCTGGGCTCTCTGATTCTCCCATTCCCCCTTCTCCTCCCAAGCTCATGCACTG +TGTCTGTAGGGCCCAGGGGCTTGACTCAGGCTGGGAGAAGAGAAAGGAAGAGGCCCCACT +GCTGGGAGCAGCAGAGCCAGAGTCCCGGCACCCCTGCCTCCAGTCCATTGCTTTTATGAA +CCATGGTGGTCAGTCAGGAAGTTTCCACCTCTCTGGGTCTGGGAAAAGGTCACACAGTGA +CAATAGAAGGGGCTTGGTGAGTGACAGGATGAGGGCTCAACCACCCATGGAGGCTGATCA +GGCCAAAAACCACTACTGGTATCTTCAAGTTTTCTGTATTTATGCTCCTTAAGTAAAAAT +GCCAGTAAAAATGTGCATTCACTGCTGGTGAGGATGTGGTTTGAAAGTGGCACATATAGG +CCAGGCACAGTGGCTCACATCTGTAATTCCAGCACTTTAGGAGGTGGAGGTGGGCAGATC +ACCTGAGGTCAGAAGTTTGAGACCAGCCTGGCCAACATGGTGAAACCCCACCTCTACTAA +AAATACAAAAATTAGCCGGGTGTGGTGGTGCACACCTGTAATCCCATCTACTTGGGAGGC +TGAGGCAGGAGAATCGCTTGAACCCAGGAGGTGGAGGTTGCCGTGAGCTGAGATCGCGTC +ACCGCACTCCAGCCTGGGCAACAGCAAGATTGCTCAAAAAAAAAGTGGCACATATAGCCA +GTGGTCACACACACTGGCATAACCCTTTGGGAAAGCAGCCTGGTAGTTTTGGCAGGGGGT +GAACATGTGGATTTGAGTCCCTCTACTGGGGTTCAAGCCTTCAGTCTGCCAGTTACTGCC +TGTGGGACCTGGGCAAGTTGTTTAACACCATGGTTTCTTCATGTCTAAGACTGGAGCAGC +TTCCTCAAATTATTGGGAATGAAATTGCGCTTATAAAGTGCCCAGCACGGCCGGGCGTGG +TGGCTCGTGCCTGTAATCCCAGCACTTTAGGAGGTGGAGGTGGGCAGATCACCTGAGGTC +AGAAGTTTGAGACCAGCCTGGCCAACATGGTGAAACCCCGTCTTTACTAAAAATACAAAA +AATTAGCTGAGCGTGGTGGCGGGCGCCTGTAATCCCAGCTACTCAGGAGGCTGAGGCAGG +AAAATCGCTTGAACCTGGGAGGCAGAGGTTGGAGTGAGCCGAGATTGTGCCATTGCACTC +CAGCCTGGTGATAGAGTGAGACTCCATTTCAAAAAAAAAGTAAAAATAAAAATAAATAAA +TAAAATAGAGTGTCGGGCAGACAGGAGACAAGAGTTCACTGCTATTAGTAGAAGTGATAG +GTTTCAAAAGCCATAAAGCCTTTTGTATGGCTTGGACCTAGTAAAGACATTGTTGAAAAT +GTATCCTAGGAAAAATAATTGTTTAAAAAATTGGGGGAGTGCTGGATGTGGTGGCTCACA +CCTGTAATCCCAACACTTTGTGGGGCTGGGGCGGGTGAATTTGAGACTGGCCTGAGCAAC +ATAGCAACTCCCCATCGCTACAAATACTTTAAAAATCAGCCAGATGTGATGGCGTGCGCC +TGTAGGCCCAGCTACTCGGGAGGCTGAGGTGGGAGGATTGCTTGAGCCCAGTGTGTGGGG +GTTGAGGAGGCAGTGAGCTGTGTTCGTGCCACTGCACTCTAACCTGGGTGACAGAGTGAG +ACTCTGTCTCAAATAATAATAATAATAAAATAAATAAACACATAATTTAAAAAAAAAAAA +CAAGGAAACAGATGTAAGCACAGAAGGAACTGCAGTGTCCAATTCCAAGCCACTGTTCAG +TGCCACCGTATCTGCAGAAGATGCTACCATTGCAAAGTCGTAACTGTGAAGGCTGTAGAG +TAGGCTAAGATATGCTCAGTGAAAAGAAGGAAGCAAGCTCTGGGCACTGTGGCTCATGCC +TGTAATCCCAGCACTTTGGGAGGCCAAGGCAGGAGAATCACTTGAGGTCAGGAGTTTAAG +ACCAGCCTGGTCAACATAGTGAAACCCCATCTCTACTAAAAGTACAAAAATTAACCGGGT +GGCAGGCGCCTGTAATCCCAGCTACTCAGGGTGCTGAAGTAGGAGAATCGCTTGAGCCTG +GGAGGCAGAGGTTGCAGTGAGCCGAGATCACACCACTGCACTGCAGTCTAGGTGACAGAG +CAAGTATCTGTCTCAAAAAAAAAAAAGTAAGCAAGCAAAAGCAAACATAGCCCGCTTGCA +TACACACACACACACACACACACACACACACACACACGGGCACGTCCACACACGTGCTCT +GGGGACAAGGATGTGAATGTAATCCATGCATGCTGGTGGGACAGCATGGGTAGCCGATTT +CCTGGAGGGCTTAGATGGGGTTTCTTTTTTATGATTTCAGTTATTCTAATCCTGCCTGTG +CAACGGGAGATGTTTTAAATTTTCAAATTTTTGTTTAAATGGAGTTTTCTCTTGTTGTTT +TGTTTGTTTGTTTGTTTTAAAGATGAGGGAGCTCAAATTCACCTAATTTGTCCACTGGTC +TCCAGGTCCCATCAGGGAGGGCACTGTGGACCGGTGATGGGGAGGCTGAACCACATACCT +CCAGGGCTCAGATCTGGGGGAGAGCTCTGGGGCACCTGCCCAGCCATGCCTGTCTGTGAG +AAACACCCCCTCAGCACCAGTCACAGCGACTGGGCCAGGCATGGGTGCCTGGACTTTGCT +GACCGATCAGAAACCCCTAACTCTACAGCCCCAACCCTGAAGGCCACAGTGGCTCTGGGA +GGCCTCCAAGGAGGCCACGAGGAGGGTGCCACGTGAGGCCCAGGCAAGCTGGGAGGGAGC +TCAGCCCGTGTGAATCTGTTGCTGGAAACCAAATGTGCCCTGAGGCAAAGTTCCTGTTTC +CTTCCCCAAATCCGAGTTTCACCCCCTTCACTCTCAGGCTTCCGGGTAGAAAAAAACCTC +TCCCTTGTTCCCTCGCCCCACAAACACCCCGGCAGATGGACACCTCCTGGCCCGCCGGCC +TCTGTACCCCTCCGAAATGGGAGTACCGCAGCATCCCACAGGAGCAGCCGCGCCCACCTG +ATGAGCACAGGTGTGTAGAGCAGGGCGGCGATGGGAGTCACGTTGATGCCCATCAGCATT +TTGCTGTCGATGTCGGGCAGCCCCATGTTGCCATACTTCACCTCGCGGTAGGTCTCGTCG +TAGTGCAGGATCAGCTGCATCTGCAGGAGGCCTGGGGACAGGACAGAGAGCGGCGTGCAG +GGAGCAGCCTAGCTTTGGGCGCCACCGAGCAGAAGACGGCATGCAGGCCTCGCAGGGAGC +TCCAATCACCGAAGGCATTCCCGCTGACAGCGCCCCTCAGGACAGCGGGGTTCCCGGGCT +GCGCCACGCCTTCTGCCAGCCCGCGGCCACTTGGCCAGCTAAGCCCAGACCCCCACCCGC +CTTGCTCCGCCGGCCTCCAATTCTGACGGTGGCAGGTCTGTCCGGGAGCCCGGACCCCCG +TCCCCCACCCACACCGAGGCTCTGGCTGGGACCCGGGGACGCTGCGCTACTTGACCCCCC +AACCCCACCCCCGCCGCGGGGGGCCGTGGCTGCAGCTGCGAGGGCAGCGGAGGGGAAGTG +AGAGCGGGCGGGAGGCGGCGGCCCGCGGTTTCTGTTTCCCGGGCCGGGCTGGGAGCGGGC +GGGGCGGCCCCGGGTCCCCGAGCGGCACCTACCCAGGTAGACGCCGTAGGTGAGCATGCC +CCCGGCGCTGGCAGCCAGCACGTTCTTGAGCACGCCCAGGCGCTTGCGGCGGTAGTAGCG +GCGCTCCTCCTCCTCCTCGTTGTAGTTGGGGTACGCGCCCACCAGCTCGTCCAGCTGCGA +GCCACGCACGCCGCTCGCACCCGCGATCGCGCCCCGAACCCGTGTCCCCCGGTGCCCGCC +GCCCCCCGGCCCGCCCCGCCCCCGCCGGGGGGACCCTGGCCCACAGGGGACGCCCGCGCC +TCGCACTCCGGGTCCCCGCTCACCGGGGCCTCGGGCCCGTCCGGGACCCCGAGCAGGTCC +TCGTCGCCCTGCGGCCCCGCAGCCCCCGCCATCGGGTAGAGCGGCGGCTCCGCCTCCATG +GCCCGAACTACTGCGGACTCGCGGCGGTCGCCCCGGAGTCCCTGCGACCGCCCGGCCACT +TCCTCCCGGCGGCCGGGACCTGCCCCCGCCCCGCCCTGTCCCGCCCTGCGGGCCGCCTCC +TCCAGGACACGTGTGTGTGTATGTGTGTGTGCGCGCGCGCGCGCGCGTGTGTGCAGGGGC +CTGCCTGTGTGTGCCCTCTGGGGTGTGAGTTCGAATCCCCACTCAGCCACCTCCTGGCCC +TGTGACTTTAGGAATTAACTCCATTTCTTTGTGCCTCGGTTTCCTCCGTTTCCTCGACGG +TAAAACAGAAATACATGGCACTACCCCCGGGGCCATGGCGGAACTATTGAGTTAATGCAA +AGCCTTGGAAAAGTGCCAGGGTTGCCTGGCTCCCTTAAGCTCCCCTCAGGGTTGCCTGGG +TCGTCCCCAGCCCCACCTCCAAGCCTGCTGTTACAGCTCATCAAAGAGCACTGCAGGGAC +AGTAGCGTCACCACCTGGACCCCACCTCCCACCACCGGACGCTACAGCCAGAGCCCACCT +CCCATGTCCCCATCCTGCTCCAGTTTGGGCTGTGCAAATGGGAGCTTGAGTGGGTCCTGG +GAGGTGGAGATTGTGATCCCCACTGAACTACATGGGGGACCCTGCCACAACCATGTAGTG +GGGCCCAGAGCCACCTGCCCCCATCCTGCTGGGCACTGGATCCCGGGCTGCAGCGGGAGC +CTGTGGTGGGGCCGACACTCCAAAGCACTGGCTACCACCGACCTGGCTGGAGCCACGGGG +CCACTTTTGAAAATATCCAGATTCTCTCCCCTGGGTTCCTTCTGGTTTGAATGCTCTTCC +TGCTGCGCCTCCCAGGTGGCTTCCTTCCCACTCAGCTCTCAGAACAAGAGACCATCCCTG +CAGAGAATGCAGTCCCTTCACTTCCCTTCTGGTTTTCCATGCCCTCCCTGTGCACCCC diff --git a/test/csq/ENST00000227471/ENST00000227471.fa.fai b/test/csq/ENST00000227471/ENST00000227471.fa.fai new file mode 100644 index 0000000..dc66104 --- /dev/null +++ b/test/csq/ENST00000227471/ENST00000227471.fa.fai @@ -0,0 +1 @@ +11 13918 25 60 61 diff --git a/test/csq/ENST00000227471/ENST00000227471.gff b/test/csq/ENST00000227471/ENST00000227471.gff new file mode 100644 index 0000000..aa86615 --- /dev/null +++ b/test/csq/ENST00000227471/ENST00000227471.gff @@ -0,0 +1,28 @@ +11 ensembl_havana gene 21 13898 . - . ID=gene:ENSG00000110057;Name=UNC93B1;biotype=protein_coding;description=unc-93 homolog B1 (C. elegans) [Source:HGNC Symbol%3BAcc:13481];gene_id=ENSG00000110057;logic_name=ensembl_havana_gene;version=3 +11 ensembl_havana transcript 21 13039 . - . ID=transcript:ENST00000227471;Parent=gene:ENSG00000110057;Name=UNC93B1-201;biotype=protein_coding;tag=basic;transcript_id=ENST00000227471;version=2 +11 ensembl three_prime_UTR 21 462 . - . Parent=transcript:ENST00000227471 +11 ensembl exon 21 774 . - . Parent=transcript:ENST00000227471;Name=ENSE00003679014;constitutive=0;ensembl_end_phase=-1;ensembl_phase=0;exon_id=ENSE00003679014;rank=12;version=1 +11 ensembl CDS 463 774 . - 0 ID=CDS:ENSP00000227471;Parent=transcript:ENST00000227471;protein_id=ENSP00000227471 +11 ensembl exon 2593 2711 . - . Parent=transcript:ENST00000227471;Name=ENSE00003531573;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00003531573;rank=11;version=1 +11 ensembl CDS 2593 2711 . - 2 ID=CDS:ENSP00000227471;Parent=transcript:ENST00000227471;protein_id=ENSP00000227471 +11 ensembl exon 4528 4801 . - . Parent=transcript:ENST00000227471;Name=ENSE00003665994;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00003665994;rank=10;version=1 +11 ensembl CDS 4528 4801 . - 0 ID=CDS:ENSP00000227471;Parent=transcript:ENST00000227471;protein_id=ENSP00000227471 +11 ensembl exon 5519 5701 . - . Parent=transcript:ENST00000227471;Name=ENSE00003597638;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003597638;rank=9;version=1 +11 ensembl CDS 5519 5701 . - 0 ID=CDS:ENSP00000227471;Parent=transcript:ENST00000227471;protein_id=ENSP00000227471 +11 ensembl exon 6592 6609 . - . Parent=transcript:ENST00000227471;Name=ENSE00002485200;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00002485200;rank=8;version=1 +11 ensembl CDS 6592 6609 . - 0 ID=CDS:ENSP00000227471;Parent=transcript:ENST00000227471;protein_id=ENSP00000227471 +11 ensembl exon 6612 6715 . - . Parent=transcript:ENST00000227471;Name=ENSE00000824041;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00000824041;rank=7;version=1 +11 ensembl CDS 6612 6715 . - 2 ID=CDS:ENSP00000227471;Parent=transcript:ENST00000227471;protein_id=ENSP00000227471 +11 ensembl exon 7275 7368 . - . Parent=transcript:ENST00000227471;Name=ENSE00003692215;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00003692215;rank=6;version=1 +11 ensembl CDS 7275 7368 . - 0 ID=CDS:ENSP00000227471;Parent=transcript:ENST00000227471;protein_id=ENSP00000227471 +11 ensembl exon 8089 8221 . - . Parent=transcript:ENST00000227471;Name=ENSE00003650035;constitutive=0;ensembl_end_phase=0;ensembl_phase=2;exon_id=ENSE00003650035;rank=5;version=1 +11 ensembl CDS 8089 8221 . - 1 ID=CDS:ENSP00000227471;Parent=transcript:ENST00000227471;protein_id=ENSP00000227471 +11 ensembl exon 8435 8596 . - . Parent=transcript:ENST00000227471;Name=ENSE00003682505;constitutive=0;ensembl_end_phase=2;ensembl_phase=2;exon_id=ENSE00003682505;rank=4;version=1 +11 ensembl CDS 8435 8596 . - 1 ID=CDS:ENSP00000227471;Parent=transcript:ENST00000227471;protein_id=ENSP00000227471 +11 ensembl exon 11938 12091 . - . Parent=transcript:ENST00000227471;Name=ENSE00003663353;constitutive=0;ensembl_end_phase=2;ensembl_phase=1;exon_id=ENSE00003663353;rank=3;version=1 +11 ensembl CDS 11938 12091 . - 2 ID=CDS:ENSP00000227471;Parent=transcript:ENST00000227471;protein_id=ENSP00000227471 +11 ensembl exon 12573 12714 . - . Parent=transcript:ENST00000227471;Name=ENSE00003644518;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00003644518;rank=2;version=1 +11 ensembl CDS 12573 12714 . - 0 ID=CDS:ENSP00000227471;Parent=transcript:ENST00000227471;protein_id=ENSP00000227471 +11 ensembl CDS 12864 12959 . - 0 ID=CDS:ENSP00000227471;Parent=transcript:ENST00000227471;protein_id=ENSP00000227471 +11 ensembl exon 12864 13039 . - . Parent=transcript:ENST00000227471;Name=ENSE00003655820;constitutive=0;ensembl_end_phase=0;ensembl_phase=-1;exon_id=ENSE00003655820;rank=1;version=1 +11 ensembl five_prime_UTR 12960 13039 . - . Parent=transcript:ENST00000227471 diff --git a/test/csq/ENST00000227471/insert-splice-vs-frameshift.txt b/test/csq/ENST00000227471/insert-splice-vs-frameshift.txt new file mode 100644 index 0000000..93ede6a --- /dev/null +++ b/test/csq/ENST00000227471/insert-splice-vs-frameshift.txt @@ -0,0 +1,3 @@ +6609 A AG splice_acceptor&splice_region|UNC93B1|ENST00000227471|protein_coding +6609 A AG splice_acceptor&splice_region|UNC93B1|ENST00000227471|protein_coding + diff --git a/test/csq/ENST00000227471/insert-splice-vs-frameshift.vcf b/test/csq/ENST00000227471/insert-splice-vs-frameshift.vcf new file mode 100644 index 0000000..45fe4f4 --- /dev/null +++ b/test/csq/ENST00000227471/insert-splice-vs-frameshift.vcf @@ -0,0 +1,7 @@ +##fileformat=VCFv4.2 +##contig= +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO +11 6609 . A AG . . EXP=splice_acceptor&splice_region|UNC93B1|ENST00000227471|protein_coding;type=ENST00000227471:67765163-A-AG, ambiguous case in 2bp intron diff --git a/test/csq/ENST00000256452/ENST00000256452.fa b/test/csq/ENST00000256452/ENST00000256452.fa new file mode 100644 index 0000000..ea07eb8 --- /dev/null +++ b/test/csq/ENST00000256452/ENST00000256452.fa @@ -0,0 +1,953 @@ +>3 3:3111213-3168317 +GTCTCTTTTGATATGGGGTGATATATTAGCTCTATTATGCTTTTAAATTAGTTGGTTTCA +AATGATGTATCCTGGATCAGGCCTCTGGAGCTTGAGATAATTTCTCTCTCTCTCTCTCTC +TCTCTCTCTCTCATACACACACATACACAATCTACCTAGAAAAAGATCATTCTAGAATGT +AGGGGGGTGAGGAATTTGTGGCTCTCACTTGCTATAGAAAAGACAGTCTTGAATCCAAGT +TCATGGTTCACTCCAGGCTGATGCAAAATGCTTTCTTCCTCAGATGGTAGCTGAGTGCTA +CAATTGGCAGCTTAAACAGCCAAACGGGCACAGCCAGAAGTAAATACAGCTGGACGTTAG +CCTTAAAAGCTGTCTGTTGTGAATGAAAAGTCTGAGGTGAGTCAAGCAAATTGCAAAGAT +TGGCAGGTGAGGAGGTGCTACCCTGTACGGCATGGGGAGAAAAAACATGGCAAAATGCTT +GGATGAGTCAACTTCCCTGCTGTAGGTGAGGCGATTTGGATGAAGCATCCATACTTTTAA +GAGATACAAGACTGGTGTGTCTGGGTGTATTGCTTCGCAGGTAAATTGAGTGTTGCCTAA +ATTCTGAACACCTCTTAGCCAAGAGCCAGCATCCCTGTTCTTTTCACTGAGGCACTGAGG +CATGTGTGAGTTCATCAGAGGATGCCAAAGTGACAGTCAAAACACAGAATCCTCCAGGGT +CTCAACTCCAGGCTTCTCTATATAACAGATGACTTCAATTTCCGTCTCACTGGACCCAGC +TTTCTGCAAAACAAATCATCTTTCCTTAGATGTCTTTTAGAGAACTTTTGGGTTCTTTGA +AATCTTTACAATTGGCTTTAAGTCTATTATTTTTTAAATAAAAATAGTAAATGTTCACAA +AGAAGATGTGAAAAATAAAGTGGGAAGAAGAAGAAAATACCTAGCCATACATCTATCTCC +CAAACACAGCCCACTGCTTCTCCTAAGCCTTTCTTTCTAGGCATAATGTTTTCTTTAGAC +TTACTTGAAGTCATATGGATACACATCTTTTTTTTTTTTTTTTTTTTTTTTTAGACAGAG +TCTCACTCTTGTCACCCTGGCTGGAGTACAGTGGCATGATGTCGGCTCACTGCAACCTCC +ACCTCCCAGGTTCAAGTGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGACTACAAGTA +CACACCACCATGCCCGGCTAATTTTTGTATTTTTAGTAGAAACGGGGTTTCACCATGTTG +GCCAGGCTGGTCTCGAACTCTTGACCTTGTGATCCCCCCGCCTCGGCCTCCCAAAATGCT +GGGATTACAGGCATGAGCCACCACGCCCGGCCGGATACACATCTTTAAAAATTGATTTTT +TTCTCTCTGACATCACTGATTGTAAATTACATTGTTAAATGTGCTTTGGCGGCATCACTT +TTGATAGCTTCATCATATTCCTTCCATAATTTACTACAGTATCCCCCTAACTTTGGACAG +TTCTGACCCATTTTGGCTATAATGAATAGTGCTGATAATAATTGGAAAATTGGTAACAAA +AAATAAAATTGCCTGTAAGAGATCCTATTCCTTTATCTCATTTACTCATCCAAAATATTT +TTTACTATCTGCTCCACACTAGCCACAGTGCCGTGTCTCGGGAATTCACTGATGCACACA +GCAGGCATGGCTCCTGCCTTTATCCATTTTACTGTTAATAGTTTACGGGCAACCTAATTG +GAGGAGGAACCCTCTCTTGGCCATTGTAGAAACAAGGAACAGCTGGAAACCAGTCTCATA +AATTGAAAGCTCAGGCCAGGTGGCGTGGCTCATGCCTGTAATCCCAACACTTTGGGAGGC +TGAAGCAGGCGCATAGCTTGAGCCCAGGAGTTGGAGACCAGCCTGGTGAGATCTTGTCTC +TATAAAAATTGTCTAAATAAGTAAATTATCAGAAAATTCAGGATATGCTTTTTTAGAATA +AGCCTTTCTTTTTGACTGCTAAAGGCCAACTTTCTTCCTTCACAGTGTGTGTGTGTGTGT +GTGTGTGTGTGTGTGTGTGTGTGTGTGTATTTTTTTTTTTTGGCAAGTTCTGGCTACATC +ACCCAAGCTGCAGTGCAGTGGCACAATCTCAGCTCACTGCAACCTCCGCCTCCTGGGCTC +AAGCCATCTTCCCACCTCAGCCTCCCGAGTATCTGAGGCTACAGGTGTGCACCACCGTGC +CTGAGTAATTTTTGTATTTTTTGCAGAGATGGGGTTTTGCCATGTTGGCCAGGCTGGTTT +CAAACTTGTGAGGTCAAATGATCTGCCCATTTTGGCCTCTCAAAGTGCTGGGATTACAGG +TATGAGCCACTGTGACCGGCCCTTCACTGACGTCCAAATTTCTAACTGAGGTCTGAACAA +GCAAAAACTTGCTTCTAGGGTGGCAGAGCTCCTCTAAGTCCTGGGACTTTGGGCACCCAC +CCCAAGCTCAGAGGTGCACATTACCATGAAAAGCAGAGGGTTTCCTTTCCCACTAGCCAA +ACATTTCCCAGTGGCCACTGCCCATAGCACCAATGTGCCCTCTTGTCACCCTTGTAGCAC +AGCCTCTGAGAATGGGTTGGATGGCTTTTGTCCTTGGACGTGGAGGCTGTGCACGGCCTC +ATGGGGCCCAGCTGTAGGCAGCTCTGCACTGGCTCTCATCCCCTCTCAGGTGGAGAATTT +AGGCCATAGAGCCCACAGCACCAGGCAGTACTTCATTTCTCCCATTCTGTGTGCTCTTTC +TTTCTTCTCTCAGTCTCTAACTGCTTTGTTTTTATGTGAAACTCTGCAATGTGAGAAGAG +AATAAGTTGTCCTGAGAAGCCAGGCGCTGTGGAGTGCCGTCATTCATCCTCTGCTTATTC +TGAAACCAGCTTGTCTGCCCCAAGTTGTTATTTTACACACATGACTTGATTTTAATTAAC +AACAAATCACAACCTTATACAATAAGCTTTTATACCAGTTTATTTCACCAACTTCGGAAT +ATTAAAGGAAATCTTTTGGGGCTCTGTAGGGAAATTAGATACCAGCATTAAGATGTTCCA +TTAAGAGGCCAGGACAAATGACTTCAGTTGGCTGCTTAAACTAGATGTGGGCTGGGTGCA +GTGGCTCATGCCTGTAATCCCAGCACTTTGGGAAGGCTGGATCACTTGAGGTCAGGAGTT +CAAGACCAGCCTGGCCAACATGGCGTAACCCTGTCTCTACTAAAAATACAAAAATTAGCT +GGGCGTGGTGGCGGGCACCTGTAATCCCAGCTATATGGGAGGCTGAGGCAGGAGAATCAC +TTAAACCCGGGAGGTGGAGGTTGCAGTGAGCCGAGATGGTTCCACTGCACTCCAGCTTGG +GTGACAAAGCGAGACTCCATCTCAAACAAACAAAACCAGATGTGGTTACTCAGGGGTAAG +TGTGCTAGAGCAAGGAGGGACTGGCAGCACACATCCAGAACAGGCACCAAAGCTCCACCC +TGGGGCCCACTCTTCTTCCCAAAGAACTCAGTGAACAAGAGCAGATGGGCCATTCCCCTG +ATAAAGGAGAACACAAAGATCCAACCATGGGCAGAATGATTCTTTTGCCAGCCTCCATTC +TCTACTTCAGTCAGCTAGTAACTGTAACTGTCTATAAATCCTTCCAATACCCAAACTGCA +AATGCTAAGGAAAGTTCACCACTTATTGAAATTAATCATTTTGGTGAGTTTTTCCACGAA +CGCTTTCTTTTCCCTACAACCAGTCACCAGGTGGTTCATCCAATCATGAGTTACTTCATT +TGAGAGAAACCTAAATTTGCTAAGAAAACTGTTTGATCTAAATCAAGGGTTGGCAAACTA +CAGCCGCGGGCCAAATCTGGCTTGTTGCCTGTTTTGGAAAATGAAGTTTTACTGGAGCAC +AGCCACGCTCATTCATTAGCACATTTTCTGTGGCTACTTTCACACTACAATGGCAGAGTT +GAAGAGGTGAGACAGAAACCATTTGTCCCTCAAATATTTACTACCTGGCCCTTTACAGAA +AAAGTTTCTTGAGCCCTGATCTAAATAACCGTTCACCTTAAGGATAAATTTGACAAAGTG +CAATAATCATACACTGAAAAATCACAAACCATTGCTGAGAGAAGGTAAAGAAAACCTAAA +TAAATGGAGTGATATGCTATGTTTATAGATAAGACTTAGGATGTCACTTTTCCCCAAATT +AACTGACAACTCAACACAATCTCACCCCAAATCCCAGCTACCTTTTTTTGTAGAAAATTG +TCAGCTGAATCTAAGATGTATATGAAAATGCAGAGGACCTACAATAACCAAAACAAATTT +TTAAAAAATCACTTTTGGAGGCCTTCCACAAATGGTCTCGTGGTTTACGATAAAGCTACA +GTAATCAAGACAGTATTGTATTGGCATAAAGATAGACAAATAGATCGATAAAACCAATCA +GATAGTCCAGAAATAGAACCAACTACATACAGCAACTAATTTCCTACAGAAATGCCAAGG +CAATTCACTGGGGAAAGGATGATTTACTCCAACAAATGATGCTGGAACAATTGGAGAGCC +ATAACTAAGTGACCACTGGGCTGAACCTAAGCGCTCTGAATGGTGAACAGGCCTAAGAAA +ATGCATATTGGGTAAAATAATTTGCCTTTTCTATGGTCTTTTTTATACTAAAGAGCTAAA +GTTCCCTCTGAAAATTCTCTATTAACTAAGATATTCATGTGGAAACATGGAGTCTTAAAA +CATTAGAGCTAAGCAGAACATTGTACAATCTCATCTGTGTCCCTTATTATACCAGAAAGA +AATTCAGAACTCAGAGGGTTGAAGAGATTGTCCAAAGTCAGTTAAGGCATGGCTGATATG +AAATTAAAATTTAAGTCTAACTGTCAAGAACACTTATAACTCAGTACCTTTCCAATATGT +CAGAAGAGTAATGAACGTGCATAATAAAACAATCAGGCAAGCAGGCATGGTGGCATGCTT +CTGCAGTCCCAGCTACTTGGGAGGCTGAGGTGGGAGGATCGCTTAGACCCAGGTGTTTGA +GACCAGCCTGGACAACATAGCAAGACCCCATCTCTTAAAAAATACAAACAACTGAATCAG +CCAAAGAACAGAATGACTGAAGCAACAGAAATGCTCCTGGCCTTCTGAGTAAAAACCCTG +CCTTATAATATAGAAAACTAAGAACCGAATGACAGCTCCCAGGGGACTCAACCCTGGACA +CATACGGCATATCATAAGAACTTTCAACATTACCTCATAGTTAGTGGTTACAAAGAGATC +TTTGATATTACTTTTTGGTGCTGGAATTGGTGGAAACAACTTGATCCATAAATGACATCT +GAAAACAGAGTAAAGAAGGAATTAGGTGAGCATGAGTATACCTTTTGTCTCTAAATATCT +ACTCTAAAAATTGACCTGGTTGATTCTAGAACCTGCTGTTTTGTAAATTCAAAATCTTTA +CGTACCAAGACTTCCAAAATTATAGGTGAAGACTTTGTGGGTACCGCAAGCCTCTGCTGT +GGCCCTGAGTCATCCAGGGAAGACCAAATGGAAACTGCTTTGTGTCAGTGGGTGTTACCA +GGCCTAATATCTGAAAACGAACTGTATATTTCAAGTGGGTGGTGCTGATTGAAGCATTCC +TTCCTCAATTATGTTTACTCACAGAGTTTACTTACTTTTTTTTTTTTTTTTTTTTTTTTG +GTCTTGCTCTGTCACCCAGGCTGGAGTGCAGTGGCGCCATCGTGGCTTATTGCAATCTCC +ACCTCTCGGGCTCAAGCAATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGACTACAGGCA +CATGCCACTGCGCTCAGCTAATTTTTGTATTTTTTGTAGAGACAGGGTTTCACCATGTTG +CCCAGGCTGGTCTCGAACTCTTGACCTCAAGTGATCCTCCAGCCTCAGCCTCCCAAAGTG +CTGAGATTACAGGCATGAGTCACCATCCCCAGCCGAGTTTACTTTCTTTTCATCTCCTTT +GTACTGCCTTCCCCCAAACTGTAGATGCCATCCGAATATAACGTTTATAATAGTAAAGCT +GTTTAATAGAAAAGTCTTTTTTTTTTTTTTGAGACACAGTCTCACTCTGTCCCCCAGGCT +GGAGTGCAATGGTACGATCTTGGCTCACTATAGCCTCCAACTCCCAGGTTCAAGTGATTC +TACTGCCTCAGCCTTCCAAGTAGCTGGGAATACAGGCACGTACCACCACGCCCAGCTAAT +TTTTTGTATTTTTAGTAGAGACGGGGTTTCACCACATTAGCCAGGGTGGTCTCGATCTCC +TGACCTCATGGTCCACCCGCTGTGGCCTCCCAAAGTGCTGGGATTACAGGAGTGAGCCCC +CACACCCGGACCTTATAAAACTCATTTTCTAAATTATGAAAGGGCCAAGACAAAACATGT +TTTTAAGCCTCCTAAAAGGTCTTGTGCCTTACTGAATGCTAAAATGGGTAAGGGATACTT +ATGGACCATTTGTGGACTCTAGGATAGGATACCAGATCCACATGCGATTTCTAGAATCCG +TGTTTGACCTAATAACCATCAGCCACTCAGGGGCCTGGTGACTTGATAGCTGAGGATGAT +GACATGCAGGCATTGTGGTGATTTTAGCCTCCCTGAGCTGTGAAAAGCCTATACTGGCAG +CTTACCCTAGACAGCCAAGGACCGAGTGGAAGACTGAGAAGGAATCAAAAGAAACCCGCA +AGTAGAAACCTTCACAGAAATTAAAAGCTGTCGACAACTTCAGGTAGGAGTGAGTGATAG +CTGAGGGCTGCATTGTGTGCTCTGTCCAACTTCTGTAAATCACCTCTGGACATTTCCACT +TTTGATTTGGCCTACACTCATCTTGGACAGGTCATCTAGGCACAAAAATGCCACAAATTT +TACCTGATAATAAGAACCCTCTGCCTACCGGATGCATGGTAAGCCTGTAAAAATGCAGTA +CTGAAACCCCACTGCAAGCACGCAAATGTAAAGAACACTTACATTTTACAGATAAGCGAG +AGAATTAACAAGATGAAGCAGATGGTTGCCATAATCACAATGACAAACCACTCTCTCAAG +GGCTTGTGTTCATCATTTCCTGGTGGAAAACAAAAAAGAAACAAAAAAATATAAAGTCCA +AGTTAGAAGCAGCAGGTAAAAGAAATGATGAGGCTTGGGTCATCAGACAGCTCAGGTTTG +AGTTGCCGGTGCTGGGTGGTGTTGGGCAAGTAGCTTAACTTCCCTGAGCCTAAGATTTCT +CATCTGTAAAAGAAGGGTAACAGCCATCTCACAAAGTTGATATAGGGTGAGATGAAATGA +TGGCAGTGAGGCCACTTTTATTCTTAAAGAATGATTTATTCAATCAATCAGCAAATATTT +ATGGCATTCATTCCATGTACTGTGCCACTTGGATCTTGGAGCTTATCTGTTTTTGGTACG +TAGTAAGGTTTTTAGATAGAAAATCCACAAAAAGATAAGCCTATTGAGTAACCCAATGGC +ATCACAATCAAAATACAAAGTTGGAAATTAAACTTTTGGAGGAAGTAAAGTATGAGATAA +TACTTGTAGTGAACAATAAAGGCATCAGACTCCAAGTGCTTTTCAATCTTAAATATCTTC +AAAGCACCCCTTACCATTATTCCCATTTTACAGACATGAAAGGAATAAAACTGCCATTAA +GTCAGTACAGAAAGTCAGTATTTTGTATGCCACTTATTCTCTGTTTAAATTTGCTTTGAA +TCTACATTTAAGGGACAGATTCTTCTAGGAACTTCTTTTTTTTATTATTATACTTTAAGT +TTTAGGGTACATGTGCACAACGTGCAGGTTTGTTACATATGTATAAACGTGCCGTGTTGG +TGTGCTGCACCCATTAACTCTTCTAGGAACTTCTATGATAGCTTTGGGGTGTGTAATTTT +TCTTTTAAGTACTAGAAAGGCGTCCAAGACAAACTCAAGCCAAGTGCAGTGGCTCACGCC +TGTAAATCCAAGCACTTTGGGAGGCTGAGGCAGGTGGGTCATTTGAGGCCAGGAGTTTGA +AACCAGCCTGGCCACCATGGTGAAATCCCATCTCTACTAAAAATACAAATATTAGCCAGG +CGTGGTGGCAGGCACCTGTAATCTCAGCTACTTGGGAGGCCGAGGCACAAAATCGCTTGA +ACACAGGCAGCAGGGGTTGCAGTGAGCCGAGATTGCACCACTGCACTCCAGTCTGGGGGA +CAGAATGAGACTCTGTCCCCCACCAGCCCCCCTGCAAAAAAAGAAAAGAAAAACTCAAGA +CCATTTACCAAATAGTGTTTAAAGAGGTTATGTGCTTGCTAACCTGCCGGATTGAATAAT +GTAAATCCTGTGTCATCTCCCTGAATATGAGTTTCCTTTCCGTGGGAGAGGCTGCTCATT +CATTAATTCCTTTATTCATCCATTTAACTAATATTTACTGGGCTCCTATTATATGTTTGG +AACTGTACAAATTACTGGGATTCAGTGGTCGAAAGATCACATATGGGTGCTCCTGTCATG +GAGTCCATTAGGAAAGAATCACACTCAGCAAATAGCAACACAAGCAGTGATTTAATGACG +AGCGTGCTAAATACTGTGGTGAGATTTCAACCACACCGCACCAGGAGAAAAGGTTACCAT +GCTCAGTTTGCCATGAACTGCTTCCTCTAGAAAAGAAGAAATACATAAGTGGAATTTTCA +GGTCCTTGTTAATAGCCTAAGACTTCCAAAATAATTAAAACTCAAATCATTCAAGTGACA +GGAAGGAGAGATACCTTGGGATATAATGCTAGTGATTCCAGCCTTGCCTTGTTCTCTTGC +TTTTTTGCCTCCTGAGGACCCTTATCCAAGCTTTATCTTCTACCTCCCGAAAGTTTTAAT +CTCCTTCTTCATCTCTTCCCTTCTGCTTTCAAATATTCATAGAGTCCTTCATCTTGAATA +AGCCATGACCCTGCTTTGCCATCTCTCTCCACTGTCATCAAATACCTTCTTACTTTATTT +CCCAGTCTAAATTCTTGAATAAGGGCTAGGTGCGGTGGCTCACGCCTGTAATCCCAGCAC +TTTGGGAGGCTGAGGCGGGTGGATCACTTGAGGTCAGGAGTTCAAGATCAGCCTGGCCAA +CATGGCAAAACCCCATCTCTACTAAAAATATAAAAATTAGCAGGGCATGCTGGCTCATGC +TTGTAGTCCCAGCTACTCAGGAGGCTGAGGCAGGACAATTGCTTGAACCTGGGAAGTGGA +GGTTGTGGTGAGCTGAGATCCCGCCACTGCACTCCAGCCTGGGTGACAAGAGCGAGACTC +CGTCTCAAAAAAAAAAAAAAAAAAATTATTTAAGGGATTCGGGCTGCTTCATTTCCCAGC +TCTAACACTGCTTTTTTAATCACAGTGACTTCCTCCTAGTCTAATTCAAAAGACGCTTGG +TTTCTTTTTCCAGCTTTATTTTTACTGACCTCCTTCCTGAATTTCAGACTGTGTATAGTT +GAGCCCACCTTGAAACCGAGTCCTCAGCTTTATTGCCCATATCTCTTCTTAGATGGCCCT +TCTCCCCATTTTAATTTCGATTGGCCCTCTCCACTCATCCTTTGACCCTTTGCTATTTTC +CACTGTGGCCTATTCTTTGAACTTTGAAAAGTTTGTTTATACCACTTCATCTTTTAATTT +TATGAAGTCTTTTCCCAGGTTTTTATTCCTGGTCCTGCCTGACACTCAGCTCCAGGCCTG +GATCTTAAACTGTCCGTAGGTAAAACCTGCTCGGATGTTTCTCAAGGCTGACAACATTCA +AAACCAAACGCATGTTCTTCTTCATATAAAAACCCCTTCTCTCACTAACTGCCCATTTCA +GTCTCCATTCTTCCAAGCCCCCAGACCTGAAGCCTCGAAGTCACTTTGACTCTTTCCATC +CTTTACAGCCGCTGTCCCTTCTCCTCATTCCCTTGGTTCATGTCGTCACTGCGTACCCAG +TGATTAGTGCCGGACAGGCAGGCTTTGTCCAGTGCTTTCATCCCTGCCTATTCTGGAAAC +CTGGCTTGTAGTCTCAGCTTGCTGTGAAGGTGGTCATTCTGGGCCTCGGTTTCCTCATCT +AAACACATGGCAGTTGAAATATATAATCCATAGATCCTTCCCCAGCCAGCACCTTTTCTA +GCACCACTCACTCAGTTGAGGGTACTGTCACTTCATGTACACATACCTTTAATAAAATTG +GTTTTAGAAAAGCAGTGCCTTTTTGGGCCGGGTGTGTTAGCTCATGCCTGTAATCCCAGC +ACTTTGGGAGGCCCACAGGCAGATCACTTGAGGTCAGGCGTTTGAGACCAGCCTGGCCAA +CATGGTGAAAGCCCATCTCTTCTAAAAATATAAAAATTATCCAGGTGTGGTGCCGCATGG +CTGTCATCCCAGCTACTAGGGAGGCTGAGGCAGGAGGATCCCTTGAACCTAGGAGGCAGA +GGCTGCAGTGAGCCCATCACGCAACTGCACTCCAGCCTGGGCTACACAGCAAGACACTGT +CTCGAAAAAAAAGAAAAGAAAAGAAAACAAAAGTAGTGCCTTTTTGCTGCTGGAACTTTA +AAAGTTTATAAAGTATAAAAAAGAAAAAAGAAAAATCAGTAGTCACTGGAAGTAACTAAG +AGCTTATTTTCTATACATATTTTTGCATTCGCTTTTTCTGAGTGCTTCTAGGTGCTCAGA +TACTGTGTAAAGTGCTTCACGTACTTTCTCGATTTAATTCTTACAGCGATGCTTTGAGAT +GGACACTATTATTCTCACTGTACAGATGGAGGAACTGAGGCAGAAAAGGACAGAGTAAGT +CAGCCCAGGCCACACAGCTAGGAAGTGCGGAAGCCCAACCAGTCCGTGCTCTTAGCCTTG +ATGTAGGAATCCCATTCCCCTCCCTCCCTCTGCAAAACTGAGGGCACACTGAATACATAG +GAGCTTCGCTTCACTTATTTTAAGCATTGCTTTTCATTGAGAACTCTCCTGAGCATGATC +CCTATAGCTCTCTGTGCTTCACTGTGGGAAGCCCTGTTCTATTGTTTGTATCCCCGTTTC +TGATAAGGCTAAGTGTGCAGGCAGCTTCTCTAATTAAAGGTGGCTGCTTTGCAAACTACC +GTTTCTCCTGACATTCCCCAAACTCTAGGTGGGACTGAAGCCCTTTATTAAAAACCTATG +GCTATACTATTTATTTATTTATATGAGATAGAGTCTTGCTGTATCACCCAGGCTGGAGTG +CAGTGGCATGATCATAGCTCCCTGCAGATTCTAACTCCTGGGTTCAAGCAATCCTCTCGC +CTTAGCCTCCGAAGTAGCTGGGACCACAGGCACGCATCACCATGCCTAGCTAATTTTTAA +AATCTTTTGTAGAGATGGGGCCTCAGTATGTTGCCCAGGCTGGTCTCAAACTCCTAAACT +CAGGCAATTCTCCCACTTTGGCCTCCCAAAGTGCTGAGATTACAAGCGTGACCAACTGTG +CCTAGCCCTATGGCTATAGTATTTTTTTTCAAGTTTTTTTTTGAAATATACTTATGTCTA +TTGTTTTACAAAAAGGCATTAGCCACATTTTGTTAAATAATGGAAAACAGACCCTCAAAG +TGGCAAAGCTTTTGTCTTCCTAAATCCTACAGATCCTCGATGGTTCCAGGATTAATACTC +CGTTCTCTGGATTGGAACTGAGGGCTCTGTTAGACTTCATTTTTATTGCATTCTTTCTTA +GTTAATGTAAAGAGTAGCTGGGACAAACTAATAACAGCAAATCAAATACCGTCTTACTTT +ATTTCCCAGTCGATTTCCTGAGTAAGGAATTCAGCCTGCTTCATGGCCCCATCTCTGAAA +CTATTCCATGCTCGTAACCATTATGCAAGTATTCTGACAACCACATTCAGAAACTGCAGG +TTTATAGACACCGGATGCAAATTCAGCAAGTGGTACATCAGCAGAAAAAAAGTTATCCTG +TTTATAACTAGGTTAAACCAACAGAAAAAGTGTGGGTCCTGCAGAAAGAAGGGGCAGTGT +TGTAAATAATTATCAGGGTCACACTGTCAGTCACATTTGGGTCTCAACTTGTGCAATATC +CCCTAGCCTGATATGGCAAGTTTTGATAACAGTACCGTTTTCTTCTGACCATGATTACAA +AAATCTTTTCAGTTAAACCACTCTCAAGTTATTCACTTCAGCCCTCACTTTGATAAGCGA +AGATTCTCACTGAATTAGCAAAAATATAGAGGCAACCCTGATTTTATTTCATTAAATGAA +AAAAAGTTATTGATGCATACAAGGTACTACGTGAGAAGCAAAGTCACGGTCACTGCCGGG +AGGGAGGTGGCACATTAGTCATTTCTCCTGGCCTGGCCTCTCCAGTTGCCCCAAATGCAT +TAGGGCTACTCCCCTATAGCTAGTTGAAAACAGAACTAACCCCTGAAAACACAACCAAGG +TCGGCTTTTCCTTGAAGAAAACATAAATTGGCAGGAAAATTTTGTGCAAGCAAAAGATTT +CACATACCTATTGCGAAGTAGACATTACTTGTGGATTATCTACTGTTCAGTTACTTATTT +ATGCAAAAAAAAATGCCAGTACATTAGTGAATTAAAGTAAGCACCTGCTCTGGTTTTACT +GAAAGTAGAGCAAGGAGGGAAGATCCCACTGAGAGTATACATTCTTTGGGTCAAAATGAT +TAAGAATTTCAATACTATAAAATTTGGGAGATCCCGTAGTATAGTCTTAATTTGAATTCT +GGGGTCTCCAACCTTGGAGATTAAAAAAAAAGTATTTCGAGGTAATTTGACTCTCTGCTC +TGACTCAAGGAGAATACCTTTCTTGCCATTAAAAAGGAAGTCACAGATGTTTCTTTTCAA +GAAATCAATGGGCACTGCCATTTGGTTATGCAAAGATGGGTTTCAGAAAGAAGAAGTCAC +ACAGCCTATTCTTGTAAGGAGGAGAAGCTCTCCAGACTCCCCATTTGATTCCTGGGTGCT +TTTTAGGCATCACTAACGTAAAGCATTTGGGAAATTCAGTTGTCTGGTGTCTGGGGACCT +CAGTTTCCATTATTTTTGACATCTTAAGCATTTGACCTTGCAAATAAGCCAATAGTCTGC +TATTCTTCTATGACCCTAGAATGTATATGGAGTGGGACATGGGGTGCAGGTGGGCTGGGA +CAGTGGCAACACAGAGGGCAGAAGGACTGCAAGTATTGGACCCAAACTAGTCCCAGCTCT +GCCTCTGGGAGCTTTGTCAAGCCACTTCCCTTTTAGGGCTGCAGTCTCTCTTGATCTAGA +ATTCTATGATGTATGAAGTTTAGACTACTAGCTCTTAGGAGATGAATTTGATTTGGAAGC +CTGTTACACCTTAAATTCTGCATGTAAGTATGAACTTTCAGTGCTTACATATTGATTTTG +AATCTGATTTCAGACTCAACAATAGGTTTCCAGGGAAAAGAGCTAATTAGTAAATTGATG +GGATGCTTCCAACAGAGCAGGCCTGCTGTGTTTTTAGAGCCAGCAGGTGCTGGGAGAAGT +TCAAATGGCACCAACAGGGTTGGATAATTGAGAGGATGTCAATATGGCAGTCTATGATAC +AGGGTTTAACTAGCTTCCTGTGACTTGCCTCCAGTTGGAGGGGAGAATGGCATCATTCAT +GAATGAACATCCCAAACCAGATCACAGGCTTCCAGTGCAGGCAAGTCAGGAGCAGACCTT +TTGGGTGAGTGAGCTTTCAAGGCAGCTGTCAAATGGACTGTGGGAGGTACCTGGTTTAGA +GAAATAAAAAGAGGGCAGCAAAATGCAGCCTCAGTGAACAAAATGTGTAGAGTAGTGAAG +GACCCGGATCACACACACAGCTTGCACTATGTTCATCTGGTGGAACTGGGCTTGCATTAA +CCGAATAGAGAGAGGAAATGGAGACTGTGTATTTGTGTACGTGTGTGTATTTGTGTGCAT +GCGTGTATTTGTGTGTGCATTCAGGATCAGCTGGATGGCTCACTGCAGTACTGCTTGTCT +GCAATATCCCCCAGTAGGACTAGACTTGATGAAGTTGAGTGGGGAATTCCTCATGGCAGT +TTTCTTCTCTGCAGGCTTTCCCACAAAGCACCAAGGGCTATGTACCTTCTGGAGCCCCCC +AAGCAACCCAGAACTTTCTTCCCTATAAGGGGTTGCTGGGCCTATTTTATCAACCTGCTA +AAGCAGATGAAAGCTGGCTGCAGAGGATGTAGTCATCACATAGAAGTAAGCAACAAGGGA +TAAAGAGGGTTAGTCCTAGACCAAGTGTGGTGGCTCAGGCCTGCAATCCCAGCACTTTGG +GAGGCCAAGGTGGGTGGATCACTTGAGGTCACGAGTTCAAGATCAGCCTGGCCAACATGG +TGAAAATGCTGTCTCTACTAAAGATACAAAATTAGCCAGGCGGGGTGGCATGAGTAATTC +CAGCTACTCCGGTGGCTGAGGCAGGAAAATTGCTTGAACCCCCATGGGAGGTGGAGGGTG +CAGTGAGCTGAGATCATTGTGTGACTGCCCTCCAGCCTGGGTGAGAGAGTGAGACTCCAT +CTCATAAAAAAAAAAAAAAAAAAAGGTTTAGTCCTGGTTCTGCCACTTGCTACCAAAGTG +ACCTTCGGCAGGGTAGCCTCTCCAGCTTCTATGTCCTGCATTATAAAACAGGGATAAGGA +TCGAATGAATTAACACATGTGAAGTGCTTAGCACAGTGCTGGTACACAGGTGCTCAATAA +ATATTACTTACTATAATTACGATTAGGATGAAATGCATTGTGTCAACAAATTCATCAAGA +TAATTTCCCTTTCATCAAAGCAAGGCCAAAATTGGAGTGCTATCAGAATTCTAAAAATGC +AGAGAGATAAACTCAGGCCAGGAGAAATAAACACACACCAAATATTCTAGATACTGAGGA +ACAGAAAAGGGTATGGGTATTCCTACCCTTCAAGGATTTAGGGTTCAAAATGTTCATTAA +GATGAATCTTATGAAGAACTTGGACAGGAACATTTAGACAAGAATGGCCTGAAGAGGCTA +ACTTCATTCCCAATGGCTTGTCTGGATGGAGGCTGACAGGGTCAAGAGCTGGCAGAGCTT +CCTGCTTGCACAGCCCCCAGCCCCTCTTGCTGAGTGTGGCCCATCCTCCAGCCTCAGTTT +CCCTGGCTGGAGTAATAGCCCCCGGGGCAATGGAACATCTCGAAAAGAACCCAGGTGTGG +AGCCAATCCTCTAGCTGTGTTCCAAACCCGGATGTCCCACCTACTATCTGTGTAGCTTCC +AGCAGTTCCTTCACCTCTCTGCATCTGTTTTCTCACCTGTGTGATTAGGAAATCATGTGT +GTGATGATAAAAGATGATGTAGATGAATATGTCCTGCACAGGGGCTGGCCCCCTGACAGC +ATCCCTCCCTCCCACAAGCTGCCATCCCTCCATGAGGCAGAATGTATGCCTAGAAGGGTG +ATGTAGGCACCAATAGAGGTGGCTGCGCCTGAAAGCACTGTGGGAACTCCCTGCTCCTGG +CATTTGGAGATGAAATCTGAAAGGTCCCTGTTAGGCCTCCTTCAGGCTAGTGGGATGACC +ACAGGCGTGAGGCAGTCCGCCCCCCCTGGTGGGAACAAATGGTGGGGCTGCCAGGTGGGA +TCTAACCAGCCTGGACAAAAGGAAGCAGTGTGACCAAGCCATCTGTCTACACAGGGAAAG +CAGAACCACAATAAGCTGTGTTAGTCTTAGGTAAGCCTAAGTGGGTCTTTCATGTTGTTA +TTGGGTCAACTCTTGTTACTTTTAAGCAATTTCTGCTACTGTGTAGACCCAGTGGCTCCC +ATCTGTAACCTCAAAAGAGTTTTGCAAGATTATTTTGGAAGGCCTAGGGATAGCTCATGT +GGACCCTCCTACAACATTTCCCTTTCATCTTCCTTCGTGTTTTGCCACAGTGTGAGAATT +TAACAAGAAAAAGCTGCTGAAGGAGAGTGACGGGATCAGGAGAGACAGAGAGAAGGGATT +AGAGCTCCAGGTGGGAGTCAGAGTGCAAGGAATCAGGTTGGAGCTGCGGGACCTTGGCAC +AATGCAGGCAAACTGGAAAATGAAGATGCATTTGATGGTCCCAAAGGTGACTTCAGTTTT +TGATTCCAGGTGCCCAGGACAAAGGTACCAAGTCACCTCACACATCAGCCCATGAATATC +AAGTCAAAAGAAAAAGGCACAGGAGTTTCTCTGGGGTGGCCTTCCTTCCAGCCCATATTG +CCATAGGCCACCCTGATACCCTACCTCAACCCATTTTCCTTAAGTCCTAACAGATTCTAG +GATGTGTCACGGGACTCTGAGACCCCCACTCCACCAGCTCAAACTCCGACAGGAAAGCAA +AGGCCAAGATTTCCTATGAACAACACATCTCTATGTTTAAGGAGCTGTCTGCTGTGCCCC +TGTCTGCTGTGACCTCATGAATGAGTGATCTGAAAATTGCTGTGACCTCATGAATGAGTG +ATCTGAAAACGGTGCTGAGTCTTCTACTCCCCTGGGTGTAGGTGCCATACATCTCAAGAC +TAACGAAAGTCAAATTTGGGCCATCAAATTTTGCTTTCAGTGAGGTCAAAGCAAAACTCC +ATCGTTTCTTTGAAGGGCAATTGCAGTGATTGTAGTCTGTCACAGAAGAAGCAGTTCTCA +GAACCACTGATCCTGACCAAAGACACGGCCAGAAATAAGTGCAGGGTAGACCCACATAAG +TCTCTTTTCCTCAAGCAAGGATATGACTATGGAAAAATTTATTTTCATCATTCCTCGTTT +CACACTTGGCATTTGAGCTTCATGGATGGCGGGAAGAAGAGAAGATGATGGACTTGAGAA +AACACACAGCTTCATGAAGACCAGGGTCAGGAAACAAAAGGTTTCGATAAACAGGAGACA +GCAAAGATAACAAAGGAACAGAAGAATCCGGAAGTTAAGAAAGTTTAAAAAGGAGAAAGA +CATGTAAAAATTGGGAAGTTAGCTCTTAAGATAAGACAGAGAAGCCAGCTGATCTAGGGC +AGGTGATAACGAGTACTGATAAAATGAAACTGCTACTTCCATAAAAAAAAAAATCCCAGC +CCAGCTATAGTCCCAGCTACTCAGGAGGCTAAGGCAGGAGGATTGCCTGAGCCCAGGAGT +TCGAGACCAGCCTGGGCAACATAGTGAGACCCCTCATCTCTTAAAAAAAAATTCTGAATC +AAATTGTAGGCCTCATTTAGTTTTTTGAGAAATCTTCCAAAGGAGAAGTCACTATATCAA +AAAGACACCTAACGTGCATGTTTATCACAGCACCATTCACAATTGCAAAGATATGGAATC +CACCTAAGTACCTATCAACCGATGAGTGGATAAAGAAAATGTGGTAAACATACACAATGA +AATACTACTCAGCTGTACAAAAAGAATGCAATAATGTCTTTTGCAGCAACTTGGATGGAA +TTGGAGGCCATTACCCTAAGGAAAGTAATCAGGAACAAAAAACCAAATACCATATGTTCT +CACTTATAAATGGGAGCTAAGCTTTGGGTACACAGAGGCATACAGAGTGGTATAATGAAC +ATTGAAGACGCAGAAGGGGAGAGGGTGGGAGGAGCATGGGGGATGAAAAGTCACCTATTC +AGTATGATGTAAACTATTTAGCTGATGGGTACAATAAAAGCCCAGACTTAACCACTATGC +AATTCATCCATGTAACCAAAAACCACTTGTACCCCTAAAGCTGCTGAAATAAAACAATTG +TTTTTAATTTAAAAAATTCCATGCTCTGGAAATTCTAGGACAGGAGAGCCAATCAGGCAC +TGTTCAGAGCAAGCAAAGAGCACTCACTTGCTAACTATACCCCCTCCCTGCTGTCCCCTG +TGCTCCTTGGCTGGCCAGGGACCTTACCAACAGAGCTGGACAGCACCCCCAGCCTCTCCC +AGCTCACCTTATCTCATCAATCAAAACTTACTCTGTGTCTCATTTTTTAAATTAAATAAC +CTTGGGCTATAATGGGTTAATTAGTTAATCAAATCTATTCTAATTCACTGATTGGCTCAT +ATGTCATCTATTTGAGAAAATTGTATATTAATAGCCACTTCTTGGCTGTTTGACAACTGC +TGAGTCATTTAGTATCTCAGGACCTCCATTTTCTTACATTAAAATAATGGGGGGGAAATT +AATAACTATGAAAGGGTTGATATTTGAGTTGAGTCTTGGAGTAAAATGGAGTGGGAGGGC +TACAGCATGCTGTTTTTAAGATAAGGCAAAAGAGGAGAAAGCATAGTTAAAGGAAATGAA +TGTAGCAGCAAAATCGCCTGATGGACTCCTAGCTGAGTATAATTATTGCTGCATCCTCAA +GGGATAAAAAAGAGCCATGCAAAATGTCCCAGAGGGGCTTGGACTTCCTATTACGTTTAT +TAATCATCTTGATGAAAATGGAAAGTCTACATTGATTAAATTCACTAATGATCCTAAACT +GAGCAGAGGAGTAAATTCCAGAAAGGATGGATTTATAAGGTGAGTAGTAATATTAATCAG +CTCATCTTCATGAAAAGGATGGCAGTAAATGAAATGGGATTTGCTATAGATAATGGCAAC +GAGGTACACCTGGGGGAAAACTATAATGAGCCCAGATTCAAACTAGGAAGGTGTTATTTA +GGAAATAATAATGGTAAGAGAGCTCTAAAGTGGAGAGTGAATAATAAATTAAAAACAAGC +TTAAAATAAGCGCTCGTTATGGATCACAATTTCACTCTCAGCACTTTTGCAGTGGGGTGG +TGCAGAGGAGGTGAATGTGAATGGCAGAGGTGGAAGCAGGTTTGTAGTGCAGCACTTATA +TTTTACAGGTGAGGATGCTAAGCCCAGAGAGGTTAGGTGTAGACTGACTAGGCCAGGGTG +GAAAAACCCTGTCATGCTCGTCACCACTCTGTCCCTTGCAGTGGTGGCAGGAGATCACGA +TTCCTTCTGACAATCTAAATTTAGCCTCAGAATCCTCAATGCTGCACTCTAAGCAGTCTC +TGATTACTTTGCTCACAAAACATTACCTTTTGTCATCTCTAGCTTATAACATAGAGCTAG +ATGTTGGCAGAGCCGTAGCTAAAAACCTAGATGTCCTGAATATCTAGTGCTTCTTTTTCA +CCTAATACGTTCTAAATTCTCTACAGTCAACATTGACTATGACTTCAAAAGTCAAAGACT +CAGAAAGCATAACTAACTTCTTATCTAGGATTCTGACCTTGGTATCCATCATCTTGGTTT +AAGTTTCCTTAGACAGCATTTTAAAATCTCCAAAATTGAATACATATAGAGAGAGGTGTT +GGGAAGACACTTAGAAATAGCAATAGTTTTGAGCCAGTGAGTTTTGTGCCCCTGGGGAGT +AACATAAAGCATTTTTAAAAAGAAGTCTATTGAATTCAAGTAACAAAAATTAAACTTCCA +CCTTAGGCATTTGACAAAATTAATGACCTTGTTAAAAATTCCCTGAGACTGATTAATGCT +TCTCGTATTTGTTTCCCTCCTGGGGAACAGAGTGAATTTTCCTGGTGCAAATGGAGCCAT +GTCGAGGAAAGTCCTGTGTGTGCTGGGTCAGTTTAGTTAGGTGGGGGCATCAACCTAGGG +AGGAGGGGAGGGAGGGGAAGATTGGTCTCAACAGAATTATGAAGCAGGTGAGTTTAGCCC +ATTCTCACTTCCTTTTAGTGTCCTTTCAGTTCCCTCTCCCCAGGAAGGCTCATGCTGCTC +CTGTAAGTCTCTCTGAGTGATGTGAGGGCTACCCCTGTAAGGCTGAGCTGGTTGTGTGTT +GCACAACTTTAGGGGACGCTATTCTCCCTTGGGAACTCGGTAACTTAGCACGACCAGCCC +CCTGGCAGATTCAGAACAGTTCTCCATTTATTAGGCCTTTCCTTATCTTTCCCAGTCTTC +AGTGGAAATCTACCTGCTGTGTGTCAGATCGGAGTCATTTTCACATGGGCTGATGGGTCA +CTGCCCGAGACTTTCCTGAAGACCTACCCCATAGCTTAAGCGAATGAATTAAATAGTAGA +ACATTTTGGCATGTGCCTGAACTAAATCTCTCCTATGTATACTCTTCCAATGGTTGATGA +ATACCTCATAGGATTCATGAGAGATGGCATCCACATGCTTGATCACCCATAATCACAAAG +GTTGGCTACCAAGATGTCTTTTTTTTTTTTTGAGATGTCGCCCAGGCTGGAGTACAGTGG +CGCAATCTTGGCTCACTGCAACCTCTGCCTCCTGGGTTCAAGTGATTCTCCTGCCTCCCG +AGTAGCTGGGACTACAGGCGCGCACCACCACGCCCAGCTAATTTTTTGTATTTTTAGTAG +AGACAAGTTTCACCATGTTAGCCAGGATGGTGTCGATCTCCTGATCTGCCCACCTCGGCC +TCCCAAAGTGCTGGGATTACTGGTGTGAGCCACCGCACCCATCCCCAAGATCTCTTAAAT +AAGACTTTAATCTACCCAGCACTTTAAAGCTTGCAGAATCCTGTCCCACCATGCCAGAGT +GTCCAGAGATCAAGTGCTAGAGTCAGTTAATCTGGGGTTAGAGCCCCATCCCTGCCACTT +GTTGGCCATGCAGAACAGAGTTAAGCCAATTACCTAAACTTTCCAAACAAGTTTTTTGAT +AGGACTAAGATTATGTATTTAGCATAGTGCTTGGCAAAATAAATAAAAATTAAAAAACAC +ATGTAATCTGCTATCCCTGCTGTTGTTTTTATTTCAGATACGGTGTGGGGCAGGAAAGCT +GGATGTTATCTCCTTTATCTTGAGAACCCTAGGAAACAGAGAGAAATTATTTGTCTGGGG +ATACACAATCAATCCTTGTAAAGGCTGAATGTTAAACCTGGGCTTTCTATGTAAGGCTCC +AGTCTTCTTCCCACCATCCCATGCTCTTATAGACCTAGTGCAACAGTTAACGACGTGTGT +GTGCCTCCCCAGGCTGAATGGTTTATCATACACATGAGACGCACTAGTTGCTTTTTAACT +GTTTCCTTCTCTCATACAATGCCTATGTTGACTTGCCGGAAACACCTGGATAATAGCAAA +CACAGGGTTTGAATTTTCTTTTTTTTTTTTTTCTTTTCTTTCTTTTTTTTTTTTTTGAGA +TGGAGTCTCACTCTATTGCCCGGGCTGGAGTGCAGTGGTGCGATCTCGGCTCACTGCAAG +CTCCGCCTCCCGGGTTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACA +GGCGCCCGCCACCACGCCCGGCTAATTTTTTGTTGTTGTATTTTTTAGTAGAGACAGGGT +TTCACCATGTTACCGAGGATGGTCTCGATCTCCTGACCTCGTGATCTGCCCATCTCGGCC +TCCCAAAGTGCTGGGATTACAGGAGTGAGCCACCACGCCCGGCCAACACAGGGTATGAAT +TTTCTATCTTCAAGGTGCAATACCACATGTCCTGGGTGTGGAATTGACATCTGTGTCAGG +GTAAGACTGGAAATGTGCCCCTTCATCCATAGCTGCCATTGGGTATATTATTATCCTTCA +TGGATCTCACTGACAGAGACGATGCCCATCTTACTTGCCAAGCAAACTAGTCCATTTGAT +CGTAACATAAACAGTTGCAGAGCTAACACAGGAGTCCCGGTGATGCATGGACCTCTTTAT +ACTCTATATCTGCTAGGCTGAAGGCTCAGGGACAGATCCAGATTTTGTGGGACCCTATAG +ATTACACAGTTTTGGAATCTTCTTTTTTTAAAAAAGTATAAAGTCAAAATTAGGTATGGG +AAAATCGAAGAGATGGAGAACAGACTACTCGTTGCCAGAGTTCAGGGATAGAAGAGAGGA +GAGAGAGATGGGTGTATTTATAAAAGTGTAACAAGTGATGATGCAACTGCTCTGTATCTT +GACTGTGGTGATGGGTACATGAACTTAAACATGTGCTAAAATTGCATAGAACCAAACAGA +CACATACAAATGAGGACATATGGCTCGGCACAGCGGCTCATGCCTGTAATCCCAGCACTT +TGGGAGGCTGAGGCCGGTGGATCACCTGAAGTCAGGAGTTCGAGACCAGCCTGACCAACG +TGGTGAAACCCTGTCTCTACTAAAAATACAAAAATTAGCCAGGCGTGGTGGCATGTGCCT +GCAGTCCCAGCTACACGGGAGGCTGAGACAGGAGAATCGCTCGAACCCAGGAGGCAGAGG +TTGCAGTAAGCTGAGATGGCGCCACTGCACTCCAGCCAGGGCGACAGAGCAAGACTCTGT +CCAAAAAGAAACAAAAAAACAAACAAACAAATGAGGACATATAAAATTGATGAAATCAGT +AAGATCTGGATTACCAACACCAATATTCTATTCCACTATTGTACTATAGTTTTGTAAGAT +GTTACCCTTGAGGAAAACTGGATGAAAGAGACACAGGATCTCTATTATTTCTTCCCACAG +CTTGTGAGTGTGATAATTATTTCAAAATAAAAAGTTTAATTTAAAAAATGGATAGAAGTA +GAAACAAAACTTGGAAAAAAAACAGGCACCAGGTCTAGGAGAGTTGGCGCTAATGAGAAG +CCTAGACACTTAAAAACTTCACTGGCTTCATGGCAAATCTATTCCTGATTGAAAAGGCAG +TAGACCGAGAGAAAATTAGTCACAATAGAGATATGAAACCATTTTAAGACCCACGAGTGA +ACGGGTACGTTTCTGGGATTACCTTTTTTGATCACAAGGAAGGCTGCCAATGTAAAATAA +ACATAAGCTACTTACCCACATAAATAGGTTGGCTCCACTCACTCCAGAGCCCTGCCTCTC +TGCACATGGAGCTCACTGCTGCTCTCACTTGAACATCGTACTTAGAAAGATCATCAATTA +TTGAGATGAATGCATTGGTCATCAATTTTTCTATCTAAGTGGGGAAAGATAGCATTAGAA +GAATCTCTAGACACCTAATTTAGTTCTGCCGATTATCAGAATGGGAGGTCCTATATAGGT +CATGTGACTCACTGTTCAGCAAGTCCTTTAAAATCAACAGGGCACACATTAATTCGTTTA +TGCTAGGTGCGTTAGTGTGGATGTGTTGGCAGTCACCCTTCAGTGGAACGCTATCTTGTA +ACCAAAATATACGAAATGATCAACGGTCAAGATCCAGGTGTTCCTATCCAGGCCCAGCTG +ATGTTTCCAGACTGAAAGACTGGAGTGGCCTATGCTAGAATGCATTATTCCCTCACCTTG +TCTCTCCATAATCTATAGTCACATTACTAAATAATGTCACATGAACGCTAGATTGTCTAG +TGTTGAAATGAAGCTATTTTCTCATGAATGAGCCCTTCTTCTTTTTCCTTCTACTGATCA +TGGTCGCCACCATCCAGCTAGTCCCCTGTACCAGAGATGTGCTCCTGACACCTGTATCTT +GAATACCCCCGGAGGTGTTTCTCCCTTTTTTACTCCAGCCCTGTGACCATTGCCTATTTT +AGCTCTTATTATCTTTTGCTTGGACCTTTGCAGTAGCCGCTAACTGATATCATATGTCCA +TGTCGCCCCTCCCCACTCACATCCAGTTTTCATGCTGCTACCAAAAATCTTCTTTTACTC +TGCAAATGTAGACATATTTCTCTATTGTGTAAAACTCTTCAGTGGCATCCATTGCCCAGA +GTCATGGTTTTTAAAAAAGAAGCCACTTCTTTATTTTTTAGCAAAATCTTATAGAGCCAC +TCTGGGAGAAATCACAATGTCAGATACAGAGTCATGATTTCAGCATTGGTCTTATGTCCA +GGCATCCAGGCAGACTGAATTACTTGCCACTTGACTGAAAGAACCATACTCTCTCAAGCA +TAAAGTTACTCCTTTTCCTAGGCTGGTGCAAGTCAGGAACTATTTATTACTGGCTTGTGA +TGGGCTAAATACAGATAAAATTATGACTGCAATTTGGAAGTTTTGATAGCAATTTGACAT +TGCCATGATATCCAAACACATGATCAGTGAACTGACACTTTACATGTCTTTGGCTATATT +TAATTTTTTCTAGCAGATCATTTTTATTGTATTTGACAAAAGCACCAATCTATGGTAGAT +TAGACATTATAAAAACACACGCACACACACGTGCACACACAGTCCTTCAGTGTAAGTATT +TTGGGAAGCTCTGGCTAAGAAAGTCCTTCTCATGTTTTCTCACCAGACTAGTTTCTCTTC +ATCCTTACAGATTCCGTTCAATTCCTCTCTGCAGAGCAGGCTCTGTGCCCACACCCCCAT +CTCTAGCTGTACTGGCTTTTCCTGTGGGAGGGCAACCCCAAGGCTGGGCAAGTATGTCAC +AAGATTGGGTCACTCCATGGCAGAAACAGTCTTATTTCTCACAAAGAAGCCAATTTGTAA +ATATTTGTTGAATCTAATTGAATTGGCTTTGTCTACTCTCTGTAAGACATAAGTTGGAAT +CCTATTTTTTTTCCTAGCTTTGTGACTGTGGGAGAGTTACTTCATCTCTTTTGCCTCACT +TTCCTATAAAATGGGAATGGTAATTACATCATAGAATTATGTGAGGATGGAATAAACACA +TAATAAAGCTTGACACATAATTGATGCTCAAGAAATGTTGATTGGCTTTCTTCTCAGTTC +CTTTCCCCTTGAAATTTTTGTCTATTAGTGCTAATGAGTTTTTTTAATTGTAAAATACAT +ATAATGAAATTTACCATCTTAATCCTTTTTAAGTGTACAGCTTTGTGATATTAAATAGTT +TCACATTGTTGTGTCACCAATGTTCAACACTCTTTTAATCTTGCAAAACTGGAACTCTGT +ACCCATTAAACAATACCTCTCCTTCCACCCTCCTACCAATTCCTGGTAACCACCATCCTA +CCCTGTTTCTATGAGTTTGACTATTTAACCTCATAAAAGTAGAATCAGACAGTATTTGTC +CTTTCGTGACTGACTTATTTTGCTTAGCATAATGTCCTCAAGGCTCCTCCATGTGGTAGC +ATGTGTCAGAATCTCCTTCCTTTTAATGCTGGATAATATCCTATTATATGTATATGCTGC +ATTTTGCTTATCCATTCATTTAATGGGCACTTGGGTTGCTTCCAGCTTTTGGCTATTGTG +AATAATGCTGCTATGGACATGGGTGTACAAACATCTCTTTGAATCCTTGCTTTCGATTCT +TTTGTATATGTAATCAGCAGTGGAATTGTTGGATCGTATGGGAATTCTATTTCTAATTTT +TTGAGAATTCATCATATCGTTTTTATAGTAGCTGCATTATTTTAGTTTTTTGTTTTTTTG +TTTTTGTTTTTTTAGATGAAATGTTGCTCTGTCACCCAGGCTGGAGTGCAGTGGCGCCAT +CTCAGCTTACTGCAACCTCCGCCTCCCTGGTTGAAGTGATTCTCCTGCCTCAGCCCCTGC +CCCCGAGTAGCTGGGATTATAGTCACGCGCCATCACGTTGGCTGATTTTTGTATTTTTAG +TAGAGATGGGGTTTCACCATGTTGGCCAGGCTGGTCTTGAACTCCTGGTCTCAGGTGATC +CACCCACATTGGCCTCCCAAAGTGCTAGGATTACAGGCGTGAGTCACCCCACCCGTCTAT +CATTTTAGATTTTAACCAGCACTAGTACCAATGAGTCTGTATCTAATCCTTTGTATTAGT +TTCAACCAAAAGTATGTTCTTTCAAAACAAAAGGCCAGTAAGATTTGGTTTATATCTATT +TGGTTATATCTATAATACCTGGGTAGATTAAGTTAACTTTGACCTTGTTAGTACCAAGCT +GTAACTTGGTTGCAGTCACTGAAGATAATTTTTTAAATGTTTCTAAAACAAATGTCTGTT +ATCAAATATTGGAATAATCTGAGTAATTACCTGCAAATATCCATTCCTTGTATTGTGTAT +TTTTACTTCATAATCAAAGCAATGGATTGGAAAAGCAGACACTGGTTTCTCCCATTGGAT +AGAGAGACGAGTTCCTTCAATCTCTGCTGTGACATTCAGTGGAGGATTTATTTGATCTAA +GTTAGGGAACGAAAGATCAGTGATTTTTTTTTTAGAATCAGTGATCAAAGCTGATAATTC +CAATCCACCCACACTTCTCAAGGCATTTCTAAGATACGCTTTTTTCAAATATTTACCATC +AGGTCTTAATCAACTGATCTCCAAGCCACAGGAAGCCGGTGGCCTCCCATAATACTCTTG +TCTTATAGTGCTGAAGAAGAAGAGACCCTTTCTGGAAACTACAAGGATTACTACTCCAAA +TAGAGTTGAATGCTTGAATTACTTCCCCCCCTCAGCTCATTGCAAGACTCACCCACCATC +CCCCTTTACTACTCAAGTTGTACCAGGCCCAGAATAAACCTGACCACTGAGAGAACATTT +CCCTGGACCTTCCACCAAGCCTTGCCTCTTCCCAGTAGGTATGTGGCCCTGAACAAATCA +CTTCCCCTTTCTGAGATTCAGTTTTTAATTTTAATTTCATTTTGTTTACTGCGTCTTTTG +GTTTTTGTTTGTTTGGGGGCTGGAGCAGGAAGCTTCAGTTTTCTTTTGCATCAAAAAGAA +TGGATTGGGGCAGGGCGTGGGGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGG +CGGGTGGATCACGAGGTCAGGAGATCGAAACCATCCTGGCTAACGTGGTGAAACCCCCTC +TCTACTAAAAATACAAAAAATTAGCTGAGCGTGGTGGTGGGCGCCTGTAGTCCCAGCTAC +TCAGGAGGCTGAGGCAGGAGAATGGCGTGAACCCAGCAGGCGGAGCTTGCAGTGAGCCGA +GATCGCGCCACTGCACTCCAACCTGGGTGACAGAGCAAGAAATCTGTCTCAAAAAAAAAA +AAAGAAGAAGAAGAAGAAGAAGAGTGGATTGGGCTAAATTTGTCTTTACTTAGGACTCTA +ATGTCCTTTCCCTTGAGATCTCACTTGATTGTCTTATGGTCCGGTGAGGTGAGGGGAAAT +GAATTCTTAATGAGTGTCCTTGTCTTAGGTAATATGACTTAGATCTCACAATTAATAGGG +AAAAGCTAGGAGTGGGATCCACTGGCTTCAGAGCCTCCTATACCCTATGAAGAAAATTCT +TAACCAAGAAAGTACTTATTTATTTTAGTAATCCTAGGAATCAGCCTCAATAAAATGAAA +ATCATAAAAGAAAAATGAATTCCTGTGGTCTGTACTAGATCATATCCATTTTCATATTAA +TATCATTGTTTCCTAGGTCTTCCTCGGCATCTTTTATTGCCTATTTTCATGAAAGTGACA +TTTTTAGTTCACCTAAGAAATATATTACTGGAGAGAATTGCATAACCTCTTTAGTAAGGG +CTATGATTCTTTACACAAAGTTATATTCCATTGGATATAGATATGTCACAGCCAAATCAT +ACCTTCTAAATAATATTGTAGTGTATTTATTAAACCTTTATGCCAGGCACTGTTCTAAGT +GCTTTATCATTAGTAACACAATTCTCACGAAGACTGCACAGGAAGTATTGATTCCTCTCC +ATTGTTTCAGATAAGAAGATTAGGCACAAAGGAATGATCAGCTTGTCCAAGGTCACTCAG +CCAGTGGTGGAGCCAGGATCCAAATCCAGGCAGTCTGGCCCCACAGCCCATAATAACCAC +CCACCATTGAAATCTGGAATCTCCATAACTAAGAATGCCATGTGAGAGCGCCTGATGAGT +TTCACTAATAGAACTATCTGGGATGAGGGAGAGTGTCTTCTCTATTGAGAACTGAGCAGA +CAAAACCACGAATAGAATTTTTAGAGCTGAGAATTGCACACTGAGAGATATTCGAGCTGC +AGAACATCCAGGAGATGGGCCAGAACAGTGAGAAATTCAGAGAGAGAGAGATGTTAGCCT +GGGAGAAGAAGGGCTTCTGGATGGGAAACGTGCTGCCTGTGAACAGCTAAGAGAGGCTAT +TCTATAGGGAAGGGACTCAAATCACCTGGGGTGGCACTAGTCCATCACAGGACCCAGGGG +CAGAAATTTCACAAAACCTGTCAGAACTCATGAAGGATTAAATGGTCTCTTTTAAGCAGC +TAAATTCACTTTTTCTGGTGCAGTGATTCTCAACTGGGGGAAATTTTACCCCTTGAGGGG +CATTTGGCAAAGTCTGAGACTTTTTTAAAAGTCACAGCTCAAGGACAGAGGGGCATACTA +CTGGCATCTAGTGTGTAGAGGCCAGAGATGCCGCTAAATATCCTACAGTGCCCAGCACAG +CCCTCCATAACACAGAGTTGTCCAGCAAAACTCACTGGTGGTGTTGGAATGGAGAACCTT +GCCCCAGTGGTTTTCAAACATGGGTCTGATGCTTACTTGGCATCAGAGAAGCAGTAAAAC +TAGGTGATCTTTATAACCCTTCCTTCCAGTGCTGAGATTCCGAGATTCAGTTATTTCAGC +TTTGGGTTAAGTCGGTCTTACCAATGGCGTGAAGGGCAAACAGCTGATCAAAGGGCCTGA +TAGCAGAGTGCTTGCTGGAGCCGTTAACAAGCACCGCAAGCCAGTCACGCCCTTTGCTGA +GGATAAAAGTCCTGGGAAACCAGCATGCGATATTTCTCCCCAGTGTGTCTTTGCTGTATT +CTTGGCATTCTTCAGTCCAAGAGCCATACCTAAATTGGAACATTTACGAGTGTTATGAGG +TTGCAGGAAACAACCATTTGCCTAAGTAAAAATAGGTACAGTACTAACCTATAGTAGAGA +AAATACTGCGTGTCCTCAGGGGCATCTGTGCCAACAAGCCAGGTGCAGTGAAGGGAAACT +TGGTATGACCTTAAACGTGAATAATTGTCTTCTGTAGTGTTTGTGGTGCAAGTTAAATTC +ACAATTGAGGTTCCAGGAGACCCTAGGTAGTCAAAAGTAAAAAGGACAAAACATTGCCAT +GGCAAACTCTGAATTTCATGCTTCTTTTGGAACTATAGTGATGTGAACGTCGTATTCATC +ACCAAAAAATAATCATCTTCACATTTTTTTTTCCCTTGAGACAGAGCCTCACTCTGTCAC +CCAGGCTGCAGTGCAGTGTTGCGATCTTGGCTCACTGCAACCTCTGCCTCCTGGCTTGGA +GCGATTCTCGTGCCTCAGCCTCCCAAGTAGCTGAGATGACAGGTGTGTACCACCACACCT +GGCTAATTTTTGTATTTTCAGTAGAGCTGGCGTTTCACCATGATGGCCAGGCTGGTCTTG +AACTCCTGACCTCAAGTGATCCACCCACAGCCTCCTAAAGTGCTGGAATTACAGGCATGA +GCCACCATGCCCGGCCATGATCACATATTTCTAGAAACCTACTAACTACAAAAGGCCAAC +TTACTGGAGATATGGAATTAGAATTATAAAGTCCCCATTTCTGATATTCGAGAGCTTCCC +AGCTATTTTGTTTGGGGCCTGGGGGTGGTGTTTGTGCAATACATGTGTGGAAGTTCAAGA +GAAGTACAATATATTGTCATTTTGAGGTTGATGTCCGGCAACTTTGGTGCTCTAATGCCA +CATTTGTTAATAACTAGCTGTGAGACATTGACCCCCACTCTTCTGGGCTCTGTGTTTTCA +ACTGTAAAGGAGCGGGTTGGTACAGGAAGGTCTTGCGTATCCCTTTCCATCCTAGAATTG +TGTGATTCATTAGGTTGTATCCAAATTCTTCATGAATTACATAGGTTGCTGCTCAGAAGA +AATGAGTTTTGACAACACTGCAAGATTGCAGACTTTGCAGACTTGATGCACATTAGCATG +TTAAAGTCCTCTTTAATATACTAGGACTTGAAGAAAACCTTGAATTGGCCAGGCACGGTG +CTCATGCCTGTAATCCCAGTGCTCTGGGAGGCCAAGGCGGGTGGATATCTCTTGAGCCCA +GGAGTTTGAGACCAGCCCAGGCAACATGGTGAAACCTCGTCTTTGCAAAAAATATAAAAA +TTAGGTGTGGTGGCATGCACCTGTAGTCCCAGCACTTTGGGAGGCTGAGGCGGGCAGATT +GTTTGAGCTCAGGAGTTTGAAACAAGACTGGGCAACATGGCAAAACCCCAACTCTACAAA +AAATACAAAAATTAGCCAGGTGTGGCGGCATGTGCCTATAGTTCCAGCTACTCGGGAGGT +TGAGGTGGGAGGATCACTTGAGCTGGGGAGGTCGAGGCTGCAATGAACCAAGATCATACC +ACTACACTCCAGCCTGGGCAACAGAGTGAGACCCTGTCTCAAAAAACAAAACCTTCAGAT +TTTATTTTATTTATTATTATTATTATTATTATTATTATTTGGAAACAGAGTCATTCTGTC +ACCCAGGCTAGAGTGCAGTGGCATGATCTCAGCTCACTGCAACCTCACCCTCCCGGGTTC +AAGCAGTTCTCCTGCCTCAGCCTCCCGAGTAACTGGGATTACAGGCACGTGCCACCACAC +TCAGCTAATTTTTGTATATTTAGTAGAGACGGGGTTTCACCATGTTGGCCAGGCTGGTCT +CGAACACTTAACCTCAAGTGATCTACCCGCCTCGGCCTCCCAAAGTGCTGGGATTACAGG +CGTGAGCGACCGCACCCGGCCAAGATTTTAAATGCAACCTTTTTATGTTTGCTTCATTAA +GGATTTCTCAAATTATGTGACTAGAAAGGCTTGTTTTCATTTCAACCTCTCGTTGCTGTA +TTAACTGTTGGTCTTTAAAATACACTGTGGGAAACACTGGCCTTGTTGGTGGTTGCTCAG +AGAAGGAAACAAGCTCTTGCACCTGGGCCAGGAAGGACCGCATTCAAGTGGGAGCCTTGA +GAGATAGAAGGGGGTCTTTTGATCGTAGCTTAAGTGAGCTGTAGATCATTTTTATCACTG +TCAGCCAGTGTCTTTCAAGAAGCAGAGGGAGAAGATGATGAGAGAGAGCCTCTTATTACC +TGTAGAGAAGTTAAAGATGGATTTCTTCTTCATATCTGTGCTTTTGCACAGACAAAAAGA +AGAACTACCTCAAAGCAAATTGACTTATTCAGTTCATGTATATATGCATATATTAGGTTG +ATGTAAAAGTAATTGTGATTTTGGTCATTACTTTTGCACCAACCTAATATATATTTGTCC +ATGCATTAAATGACCAGAAAGTCCACACCCAAGTACACTTTAGAGATCCTGACAACTCTT +TGTCTTATAGTTCTCATCCAAAGAATCATTTAAGTGAATTCCACTTGGTTCAAAACAGAA +ATAATTTTTATTAGTGTCATCCTGTATCAGAGTGTTCAGAGGATAATTAGAATTGTAGAA +ATGTAAGCTGCAAAGTGCCTCATAGGTAAAATCCAGTTGTTCATTATAGAAAGGAGGAAT +GGTGGTTTGACGTAAGCCACATACAATAACCCATCTCTGTGTTCCTGTATCTACCTTGGA +TTAGTCTCTGTACTTGGGATCAAGCCCATGCAAATTGGCTGGTATGTGGTCTAGACAAGT +TATAACAAGTAAATGGGGCCGGACACGGTGGCTCATGTCTGTAACCCCAGCACTTTGGGA +GGCCGAGGCGGGTGGATGGCTGGAGGCCAGGAGATCGAGACCAGCCTGGCCAACATGGCA +AAACCCCATCTCAATAATAATAATAATAATAATAATAATAATAATAATAATAATACAAAA +ATTAGTCCAGCATGGAGGCGCATGCCTATAATCCCAGCTACTCGGGAGGCTGTGACATGA +GAACCGCTTGAACCCAGGAGGCAGAGGTTGCAGTGAGTCAAGAACACACCACTGCACTTC +AGCCTGGGCAACAGAAGGAGATTCTATCTCAAAAAAAAAAAAAAAAAGTAAATGAGAAGA +TCTTTATGTTTCTGTTTTAAGTCACTGACACAATTCAGGAGGTATGGTCTTTTCAGCTGG +TGATATGACAAAATAGTCGTTTGAAAATTACCCGTGAGCTCAACTGACCAAGACAATGGT +TATTGGGTGCACCCACATGTCCCAGGACTTGGTAGCCTGCTTCTCCTCTTTTCTCTCCCC +TGTTGTGTGTGCACTTAAGTGTTTGATCAGAAGTATTACTGACTCTAAGTATCAGAAACA +CCAACTTTCCACTGGAGGCCAATGCAGAGACAGTGGATATTTCTGCAAGAATGTGCCAGA +TGGAATTCAGTTGGTTATGATAAGAAGTGGCAGCAGCCTTGGTTAGGATGTTGTTGATAT +GGGAGAGTACTTGAGAAGAACGGGTGACTGACTAAAGAAAAGTGGGTTAGTGTTAATTTT +TCTACTTTTCCATATTTGCAAAGTCCAAAACATACAAACTGGACTTTTGGAGGCCTGCTT +TACCTGGTGGGGCATGAAGTTCAGCAGAAGCCCAGCTGCTGGCCAGTAGTGAGTGGTCGT +TCTGCAGGATGGTCCGCACACTTGCTGAAAAGCCTTTGTGGAGGATGGTTACACATTTGC +TTTCAGTGATTCTGGTTTCATACTAAAAATAAAACCCACAAGTCATGATACATAAAAGAG +AACTAGACTTAAGAGAGCTATTTTAATCAAATATGCATTTTCTTCTACTTTTTAAATGAT +TAGTAAGATGCAATGAAATAGTTTTGCTAGAAAAAAAGTCAAAACAAAACCATTGTAATA +ACAACATAGTAATTTCTCAATGACACATGAACGCATTATTCTTGTAAATACAAGCGAAAT +ATTACAGTTAAACTCAAGTTCCCTTTGAGCACCATCTCCCCAGAGGTCAATGTCGGACAG +AAAATTCTCTAGAATTCCATATTGACTGAAAAATAGTGAATATGAATCACTTCTCCCTTT +GTTTGACTTTATTGCACACCTAATATGTAGCAGGTGCCTGAATGTAGCCCCGAGGTAAAA +CTGAGGCTCTGAGAAGCTAAATGACTTGTCCCAGGTTGCAAAGGCAGGAAGTGGAAGAAC +TGGGTTTTGAACTTAGTTTCCCTGACTCTCCACTCTGCCTGCTCACTTCTTGTTTTACTA +GGCTACTGTCTCCTGTTCTGTTGGTAATTTTATGGGAAACAGAAAACCAGTACCCAATCC +ATGGTGCCTAAAAAGTTACTAAACATTCTTCCTTAAGGGAAAGAATCATCCAAAAGTTAA +AATATTCTGTGATGCTGTTTAACGCTGAACAATACACCCGGCGCTAGCTCACAGGCATTC +TTAGAGAGACACTATTCTACTGGTAACATAACATAGAGCCTGTCAGTAATTTTATTTTTT +TAATCCAAAATTTTATTTGATAAAGAAAATGCAGTCAAAATGCATATTTATTCTCAATAA +GGATATCCATTAGAATAAACACTTACGTCATCTTCTTTTGGAGCGTTTATTTTCACTTGA +TATTCTAGATTAACATTCCTTTGCTCTTGATCAGGATTTGGTTTCCATTGTAAAAGAACT +TGAGCCAAACCAGTAACTTTAATGGTGAAATTGACAGGTGGGAGAAGTGAAACTGTTGAT +TCAAAGAATAAAGAAACAACACAATGTTCAACTGGACATAGGCAGCACTTTTAAAACTTT +TCGAATATTTATTGCCCTGCAGATGCTGTCCTGGACCTGCCAGCACCACAGACACAGTTG +CTCCTGCGTGCCTGTAACACCGGGGCAAAGAGAAAGTGGCTATTTCTACCCGAGTAGCTG +GGACTACAGGCGCATGCCACCATGCTGGGCTAATGTGGGTTTTTTGGTATTTTTAATAGA +GACAGGGTTTCACCATGTTGGCTAGGCTGGTCTTGAACTCCTAACTTCAAATGATCTGTC +CGCCTCAGCCTCCCAAAGTGCTAGGATTACAGGCATGAGCCACCACGCCTGTCCTAGAAG +AGGTTTCTTCAAAACTGTTTTTAATATCTTTTTTACGTTGCCCATGTCCAGGTGTTTACC +TATAATACCTATATTTTTATTGAAATATGAACATGTTACTATATCACTATTCACTATAAC +CATAATTTTCAAACTGAGAGTCATTATCCATTAACAGGCAATAATAACAATGTATTGGTT +TGTGACCAGAATTTTTGTTTTAGTAATGTGGAAGAAAAATAGAATAGAAAATATCAGTGT +GCATCAAACATAATAAGAGCTGTTTCATGAATCTCGTTTCCACTACATAAAGGTAGTTAT +ATATTTGTATGTGTGCTGGTACATAATGTAAAAATGTATTTACCTCTTATTATGAGTCAC +AGACAAAAATATTTGCAAGCAAACTTACTTAAATAGGGCTTTACAGAAAGAAAAGGTTTC +TTCCCCCTGCATGAGCCATTCTCTGACTTTGCTTTCAAAATTAAAGCTTTTGTTTAATTA +CAAAATCAATATCTGTTTATTGAAGAAATTTTGGAAAACACAGATAAGCAGAAAGAAGAA +AATAAATTTTTTAAAATAATTGTACCACTAAGAATGGAATTAACATATGATATATTCGTT +ATGTTTTTTTCTGGGCGTATATTTATGCAATTTTTAATTTTTTTTACCACAATTAGGACG +GTATTGTACACACAACTACAAAACCTTCTTTTATTCATTTACTAAGTTATCAGGATTTAT +CCATTGACCTTAACGGACTTCCACACCTCTACATCCATGTTTACCACATGAGGACTTTTA +GAGCTCTGTCTATATTGCATTGTCCATTACGGTAGCCACTGGCAACTTGTGGCTATTGAA +ATTTTATTTAATTAATCAATTAATTTTTGAGACAGAGTCTCACTCTGTTGCCCAGGCTGG +AGGGCAGTGTTGTGCGATCTCAGCTTATTGCAACCTCTGCCTCTCAGCTCAAGCTATTCT +CCTGCTTCAACTTCCCAAGTAGCTGAGATTACAGGCATGTGCCACCACACCTGGCTATTT +TTGAATTTTTAGTAGAGTTGGGGTTTCACCATGTTAGCCAGGTGGGTCTCAAACTTCTGA +CTTCAAGTGATCCACCTGCCCCGGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACT +GCATACGGCCTAAACTAATTTAAATTCATTACCTTAGTTGCACTATCCATATTTCAAGGG +CGCAATAGTCACATATGGCTAGTGGCTACTGCATTGGACATTAGAGAGATACAACATTGT +CATTACCATAGATAGTTCTGTTGACAATGCTAGACTGGGACCATGTGATGATTTTCCTTA +AACTCTGTCATCACATCAAATACATAACATCAGCAGATTTCAGGACAAAATGCAGTGGAA +GTTTCTTAACGTTTGGTCATGGGGCCTTCTAACTACTCCCTTGTGTGAGAAGACATTCCA +AATGCGACCACTGGCGCCAGCTTTATTCCATGGTGCCCGGACACCCACACTTTGACTTTG +ATTTCCCACTGTAGCATAACATTTGCATTTCAGCCAACATTGCTTTCTTAAAATATGGCA +TGTTTAAAGCATCTGTCTTCTGATGGGGATAAATATTGTCTCATAAAAATCCATATATAA +TGTTCTAATCGACAGTTTAAGAGGAAATAATGTTATCCTTTTACTAACATATTTTTAAAA +ATAAACATTATTGAATTGAATAGAAGGTCCTTACTCTTTTCATCAGGAAGTAAGTCAGCT +TGCAGTATCTCAGTGGCCCCCAAAAGGATGAGTAATACATGCGCCACGATGATCATATCC +TACAGAAAACAAGGGAGATACCAAAATCATCTTGTTGCTATTTTTAAGAAAAACTGATAG +CTGCTTTCTAACATAAAATGCAGTCGTTTGGCCATTTAACAGACATTTATGGCATATTTG +TTATGCGCAAAAAGTACAAACATGACCAAATGTTGGACTTTGCCCTTCCAATGTAGATTC +ATAGTTTGAAGGACAGAATGAAATATAAATTGATAAATGTAAACCAGTTGAAAAACTGCC +TCAGTAAAGGTGTGTATGGGGTACAATAGGAGCAGAGACTTCTGATTTGCCATCTAAAGG +GTGAACTAGAGTCCTTGACGCACACAACAGGGAAGAGACATGCCTGGTGGAACCCAAGGT +ATGTGCAAAGCTGGAAGAGAAGGAAACAAATAGGAAGGGATTGCTTTTCGACAAGAAACC +AGAGCAGATCTTTGAATAGCAGAATTTCTAGCATAGTCAGCAAAAGAAATAAACATTACC +TTTTTCACTATGAGGATTTAAAGATGAGTGAACATGACAGGAAACTTCAATCTAAAACAA +TCTGTAGCCTAAGAGAAACTTTGTATCACCAATCCAGAATCAACTTGTGGTACTTTGAAG +AGTGTTTTTTTTGTTTGTTTGTTGATTTGTTTTGTTCCCCCCCCCACCCCGCAAAGGGAG +CGGATCACAAAAGAATTGAAAAACACAGTGATAGACCTGGGGAAAATAAAGACAGTATTT +CTATGTCCTTGAAACAATTGGGCAATGAGAAGGAATCTAGAGCTGGAAATGTGATAACCC +AGTGTGAACACACACAAAAGTCTCGGCATCCTGTTCTACATGTCAAAGAGGAGAGTCGGT +GATCTCTTTCTGGGAACTGTAGATGAGAAGTCTTGAGTTTTTCTTCTGCACATTTTGAAA +GGCATATTTCATAAGAACTTAACTTTCAAGGGCAAATAACACGCATGGCTTCCCCCTGTG +TTGTCCTCACTTTTACAAAGGAGTTCTTCCTACTCTCTTACCACGTGCTCCCCCCAGAGA +TTTGGTACCAGACACATGTGGCTGTTATACATGATGGAAATCCCTTCCATGGACGTTATT +CCTACCCATGAAGGAAAGGAGTCTGAAAGCTGAAATAATCTGCCAAAGATCAAACAGCTG +TTAAGTAATGGAGCCTAGACCCAATCTCTGATCTTCCAATGGCAAAACCTATGCTCTGTC +AACTTTATGGTACTAATTACAATGATTTATAATTTCATTTAAAACATTTATTTAAGTGGC +TTGGTATTTTCCAAATATAATTCCAGTAGAACCACAGGAGAGACCTGGGCTAAATGAATA +CCTCCAGGAAATAGCACAGAACACTCTTAACTTCATTATTACTTCTTAAATTATTACTTA +AGTTGCTACAATTACTGCTGAACTTACTAATGAAATTGGTAAAATGCCAAAACAGCAGGA +AAGGATCGGCATATAAATCACTCAATTCCTTGTCAAATAAGCTTAAGTACTGTTAATCAG +AAGTATGCCAGTTTTGATTTTAAAATCCTGTTTATTTTTCTCTGAGGATTTCACACCATG +TAGAAATTAAAAAAAAAATGAAACGATGACGATGACAACAAAAGCAGGTACTCTATAATT +TTTTTAAAATTTTCAACAAGTGAGAATTTTAATGAATTAAGGGAAAACACTAGTAATCTA +CTAAGCCTGAGAAGCAAAGATAAAAATTCCTTAAGAACAGCAACAAAGATAGCTTCCTCT +TTAAGTTATGAAGGTGATTTCTTAAAATGTCAGCATTTCCTGAAATAATATTAAATATGC +TCTGATTTTGCACTAATTTTCAATAATAGGAATTCTAGGTCAGAAAAAACTGCAAAATTA +ATATTTCTTTGTGACTTTCACTGACTGGCAAAGTAAAACTATGTTATAAATGTACTTGTA +AAAGCAATAAACATGTATTTATCCTTTGCAATTAAATTGTTGAAGTAAATGATAAAACTG +TTGAATATCTCAGTGGAGAGATAATTGAATATTTTATATGAGCAAGCACTCTCCCCTAGA +ATTTGTCATGTATTCTGATTTTATAGCTGCTAAAAATAGAATTGTTTTTCAAATTTAATC +ATTCAAAAAATTTTTGATTATTAGTTTTTGGCCATAAATAAATAGACAGCTTTTTCATGT +CTCATTGTCATATTTAAAAAGAGGTGCTTTTGAACAAAATCAGTTGTCCTATAGGCAGCA +CAAGGTACTCAGTAGGGGTCTAAATATTAAAAAGAATGACATTTTTTTTTTTTTGTGAGT +CAGATAAATTTTACATAAGGTTGAATAGTACTAGAGCTTCAGGATTTGATACCATGTTTT +CTACAATTCTGCTCACTCTCTGTGGCCCCTTAATACTTCTTGTCCCTGCTTAAAACAACA +ACAACAACAGCAACAACAAATCTCTTCAGGCCATTTCTTTAATCCAAAGATACACTGTTA +TGTAGATGTCAACTGGGTCATATTTCACTATAAAAGAATAGAGCGACTTCATTAGCTTAA +ACATATATATCGACAATATGTTCGACTCATTCTTCTCATGGCTACCAATTAAAATCTAGC +AGAAAACCATTAAATTGTTAAAATAAGATGCAAACTAAGCAGAATGAAGCAACTATAGGT +TGTTTATCTATCACCAGGAAGACATGCTCAATCTTTAAGAGAAATCATGATCTCATGATC +TACTTGCTCATATAACATTTCATTGAGTCAATCTAAAATTCCTCAAGTGCTCTCTAAAAA +TCTAGTTTCTGATAGGTGTTACATTTTTTGAAATTTTGGAGAAAACAACCACAGTCTCCT +TCCCTATAGGTGTTTCTAGGAAGTTTGGTAAAATTTTGACAATTAGCAGTGGATTTCCCC +AGCGTTCTTGAGAACTGGTCAAATTCTACTGAAGTTCAGACTTACAAATATTTTCCCCTC +TTTTTTTTCCCAACTTATTTTTCTGCCTGGGGCGTTCGTTTTATAACCAAAGTTATACTG +GCACCCCTGTTTTTAAAACCTTTTTGAGTCAACTGTGGTAACACCTAATTCCAGACTCAA +CCTTAGTGGCAGAAATTGTAAAGCAACTGAGAGGATTCATGCTCTGGTAGGCTTTTAAAT +ATGAAGAGTTTACTTTCTCTTTTATCCTGTACAGTATAATCAGCAATAAAAGTTATCTCT +TGGGGGATGAAGAATAAACCAAGGTATAAACTGCAAAAGACATGTTTACCTAGGTATATT +GCATTACCCCCCAATGAAAAACTGCACATTCCTAAATATATAAATGAATAATAAGGACCA +CTTATCATGCATGCAATTTTTTTTTACTACTACTGTACTTTTGATTAAATTTCTGAAATA +GTCCTAAAATAGAACTCATGAGTTCAGGTTGTGGCTGTAAACATAAAACTCTCTGTCAGT +CCAAGTGGAAATGGTGTTGCCACCTTGAGTATTTGGAAAAATAGAAGAAAGAGTTTGCTA +CAAATATCCCAGTAGCAAAATATTTCCTGCCAATTGCACATGGTGCAATTTGTCATCTCA +CATCCATGCTCCTGGGCGTACCTGTCTACAGACGATCCTCTTGTTCCGACCAGTACTCAA +CAGAAGATGGCGAGGACCGTGTCTGTCGTGTCTATGCTCGTGGCTGCAACCCCAGCATCT +AGCATAGCGTCAGGCACAGGACCAATGCTCAATGTGCCTGGCCCTGTGTGGAATAGAAGC +AAATTAGTGCACAGCCCTAATGTGCAATGTGCGGTGAAACCTAACAGAGGAATGAGTTAG +GTCAGGAGAGCAGCAGGCTGGGGAGTGTGTAACAAGCCTGGCCCACTTTTGGTATTTTGC +CTAAAAATTTCCCATGCGGTGTTTCAAATAATATAAACAAATGAGGTGATTTAACTTCTA +AAACTTTATTTTGCTTTGAAATGCAAACTTTTAACAAATAGCTACATAAATTCCTTTTTC +GATAACCATGAAAGAGGACATATTCACTTAAAATAGAAATCATGCCAGGTAATAAAATGT +TCAGTATGGTAATTCATTAAAGCAAGTACTAAGTACATTATTCACATGGCTATAAAAGCA +CCATCACTTTTCATGTGTTTATTAATTTTAGGCTCAAGGGTATTAAAATATTCTCGCTCT +GTCTCTCCTTTTTCCCCCTTTTTTTTGGTTCCATTTCATCCTTTTTTCTGTCTACATGGA +AATATGCTTACCTTGCTTTAGGTAAATACATTAGTGAACACAAAACCAAGTGACATATTT +CAGCAAATTTGGGTACATTTTATATACAATGAAACAATCTTGGAAATCCAAGAACCCCTA +CCAGAAAGAAAAAGCAGAACGCCTCCTTCAGTTAGATAAAGTGCCTCTCTCTACTTTTTG +TTGTTGTTTCTTTATTTGTAGATTTCTTGCTTAACTCTGAAACTTCCTGAGATATTTTAT +TAAACCCTATACCCTATTTTGGAAGCTCATTTATTTTCTAAGAAATCTTGGCAGAATATA +TGTTCTCATTTTAATTGCATAATTATCTGGAGCGGTGGAAAACAGATGTCTTATATTGAT +GTAAGCACTAACAAAACCATAGGTGTTGTTTTCATATGACTCACCTTGCCACGGATTTGC +ACATCTCACTTACTGAGCCAAAACACAAGAATAGAAGGTTATACCCAGAATCAACATGAC +CTGCCTAATGATGCAAGTTTAATGGGACCATTATTAGTTCTGTCCCTGCTAATAATAATA +GAATTATAAGGAGTTTTGTTTCCCCTTTTTGTTGTTTACAAGTTTGTCATATATTTAGAA +GTCATTGTTTCTTGCTTTTCCTAACCCTCCTCCCCACCCTGGGTGTAGTGAAATTATTAG +GAGGTGGAGCACAGGGTATTGTTACAGCCCATGTCATAGAAAAAAGATATTTATTTGCTT +ACTCTGTGGTGAGTGAAGCATTTGATTCCCACTTACTGAGAAATGCGGTGGCCATGCGAT +GAGAAGCAGCGGCAGGGCATTGAGAACGAACCTTATCTCTGGGTGCACTTTTTAACTTAG +AGGCGGTTCTTCACTCTTTCATCATCACGGCTGTAATGGTTAAAAACTCTCAGGCAGCTT +CCTTCATGATGGGATGGCAACACGTTTTCTCTAAGCAAATATGGAGGAGGATTTGTACAG +AGCAACTGTGCAGGAGCTGAACTGGAACTCCCAACAACCAAACTGCTGTCAAACGAAAGA +ATCTCTCGTCCAGATAGCCATTATCTGATAACTGTCTTGTCTGCATTTTCACTCTCTTTC +AGAGTTGGTTTGCTCTCTTCAGGAGTGGGAATTAACTTTTACTCATGGTGACAAGGTAAA +CAAGTTTTCCGTGGGTACTCTAAAGCGTTGCATTTCTGTTTTGTTTATGTGCCTTGTTTG +GCTACAGTAGTTACTGTGCCTCTGTCTCCTAGGCAACACTGACACATGATTTGATAGGAA +GTAAGGCCTGAGGAGTACCCTCTCCCCACTCACTAGGCAATAGCAGCAATTCTCTGCCCT +TAGAGAACCGCCTTAGCTCTTCTCTGCTTTGTGAGCAGGTCTGGTACCCTCAAGTAAATA +TGTGTGGGGGATGCGTTTCTGGGTGTGATAAATTGCTGCTGTCTGTCACCTGAGATCATC +CTACACAAATTGTAACAATGGCAGTGTTGGTCTGTGGGTGCACCCAAGACCACCTTCCTC +ACGTCACATCCATTTTACCACCCAGCTGTCTTCAGAATGCTTCAATTTCAGCAAACCTCC +TTGGCTTTTCCTGTCCTTTGTTCCATTTCTGTTTGATTCCTTCTGGGGAATTTCGAGGTG +GCTAGCTAGCAAAGCTGGCTTTAAAAAAGTAGCTTAGCGTGTGAATAGATAAGAGTAGTG +CTTATTGTATGACCCACGGCAGAGAGTAGTAAGTAGTTGCCTTTGGAAGGAGACCTTCAG +TCTAGCCTAAGCGATGAGTGATGCAGGATTCCCTGTCTCCTTAGGAGCTGACTGGGAGAG +TCTCAGACAGAGCAGATGCAGAAAGATGGTGGCCCAGGTTGGATCAGTGGTTCTGTTTGT +GAGATGAGAGACAGGCTTCCTGGAGGCAATTTCCAAAAGGCTCAGTGTAGAAGCTGTGCA +AGTACAGTCAGCGTGTGTGCCTGGGGTTCCCAAGGTGACCATTTTAGCAGTTGCCAAAAT +GAAACCGGAGCAATTGTTATCAGGTTGAAAATTGTTGTCAGACCTGAAAAATGTGATTTT +CCTCGGGGAAAGGGGAAGTAAAACAAGGAACAGAGAGAGATCCATTTATTTGCTAAGAGG +CACCCAGAAAAGTTTAGATATAGTATCAACTATCTGGCCTACTCTTTTAAGTCCTGCCCA +TCTGTTTATACATGTAACATATTTGTCACTAATGAAACCTTAAAAATACTTATTAATCAT +TGGGAAGACAGTAATTTCTGGCTTAAAAGCCTGCTTTAATGGCCTCTCTCCGTATATATA +TATGTATATTTTTTGAGATGAAGTCTCACTCTGTCGCCCAGGCTGGAGTGCAGTGGCGCA +ATCTCTGCTCACTGCAACCTCTGCCTCCCAGGTTCAAGCGATTCTCTTGCCTCAGCCTCC +CGAGTAGTTGGGATTACAGGCACCCGCCACCACGCCTGGCTAATTTTTTGTATTTTTGGT +AGAGATGGGGTTTCACCATGTTGGCCAGGCTTGTCTCAAATTCCTGACCTCAAGTGATGC +ACCCGCCTTGGCCTCTTAAAGTTCTGGGATTACAGGTGTGAGCCACCACACTCAGCCAAT +GGTCTGTATATTTCTTACATTCATTTACTCAAATATTCATTGAATGCACCTATGCACTAT +GCTAGGCGCGGTGAAGGGTATAAAGAAAATTAGATCTGGCTGCTCCTTCCATACCACCTT +CCTGGGTATATGATCTTTAATTAACTACGCCAATAAAAACAAACAAACAAACAAAGCAAA +CACATGCTCATACAGAAACACTGTCTCTATGTTTCTGTATAAGCACAAACGAAAAAATGA +GAGGCAGGGACTTTTTTTTTTTCTGGCGGGGGGTTGCGGGGGGGTTGTTTGTTTGTTTTG +AGATGGAATTTCAGTCTTGTTGCCTAGGCTGGAGTGCAATGGCGCGATCTCAGCTCACCA +CAACCTCCACCTCCCGGGTTCAACCGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGAT +TACAGGCCCCCGCCACCACACCCAGCTAATTTTTTTGTATTTTTAGTAGAGATGGGGTTT +CACCACGCTGGTCAGTCTGGTCTTGAACTCCTGACAGGTGATCCACCCACCTCGGCCTCC +CAAAGTGCTGGGATTACAGACGTGAGCCACTGAGCGAGGCCTGTTTGGTTTTTTATGGCA +ATAATTTAATTCTTTATAATAAAGTGTAAACGTCCAAAGACAGTATGATAGAACATGCTG +GAAGAATTCACAAAAGTCGTTTTTTTAAAAAGTGAAATTAAATGTGTCTGCATCCTTTAA +GCAAAACAATGTGAGTTTAGCCAAATAGAAATATGAATAGTAATAAAACGAAAATCATGG +TTCAGTGGCTCTACCATGAACTTTGGTTAAAGGAGCTTATTAAAGGTATCAACTTCTAGA +ACTTGATTCCATGGAAATAATGGAAAAATGTAGATCAAGATTTATACAAAAGAGAGCAAA +ATTCATTGTACCTTTACAATAGTAAAATAGTAAAAGTACTATAGGAATGGTGAAGAGAAA +TATGTAACTGCTCAAGGTTGAAATATGTGATGTGGATGTCAAAAGGAATGTTTATCAATA +ACTTTTTTTTTTCTTTTGAGACAGGGTGGTGCCCTGTCACCCAGGCTGGAGTGCAGTGGC +AGGATCTCGGCTCACTGCAGTCTCTGCCTCCTGGGTTCAAGTGATTCTCGTGCCTTAGCC +CCCGGAGTAGCTGGGATTGCAGGCATGTGCCACCATGCCAGATAATTTTTGTATTTTTAG +TAGGGAGAGGGTTTCACCATGTTGGCCAGGGTGGTCTCAAACTCCTGGCTTGTGATCCTC +CCACCTTGGCCTCCCAAAGTGCTGGGATTACAGGTATGAGCCAATCAAGAACTTTTAATA +ACATAGGGTATTATGAAAAAATGTTAAGTAAAAACAACAGGAGGGTATACACACATGTAA +TTTTTTTTTACAGTCTTATTTTTGGTCAGAAGATCAGACTAACAGGAATAGTTATCTCTA +AGTGGTAGGTGTATTAGTCAGCTATTGCTACAGAACAAGCAACCACAGAACCCTCAGTGG +TAAACTGTGATAGGCATGTATTTGTAGCCCATGTGTCTGAGTTTTGACTGGGGTCTGCTT +AATCTTGGGCTGGGATCCAGATCACAAAGTGAGTTCAGATTTGTTCCAAGTATCTGCCAT +TCATTTGGAACCAGTGGCTACCCAGGGCATAATCTTTTTATGGTGACAGCAAAAGTGCAA +GAGAGCAGGACCAACTGCACAAGCACGCATCAAGCATCTGCTCATGTCACATTCCCTGAC +ATCTCAAGAGGCTGAGCAAATTGCATGGCCAAGCCCGGAGTCAAATGGACGAAGCCCAAA +GTACATTCCACCATGATAAGGCCATGATAAGGATGTGGACATGGACAACTCCTAGTGGGG +AGTGAAGAAATGGGACCAACAGTTCATTCTACCACGGCAGGGTTAGTGTTTCTCTTACTT +TTATTCTGTGTTTCTATATTTACAAACGTTTTATTCTGTACAAATGCAGGCAGAAAAAGT +TATTTTAAAAAATATTAGAGACATACAGATCAATTTAATAGAATTGAGAGTCAAAAATAA +ACTCTCGCATTTAGGGTCAATTGATTTTTGACAAGAGTGTCAAGACAATTCAGCGGGGAA +AAGATCAGCCTTTCAATAAGTGGTGCATATCCACATGCAAAAGAATGCCTCGCAGCATAG +ACAAAAATGAATTCCAATGGGATCAAAGACCTAAAAGTAAGAGGCAAAACTATAAAATTC +TTAGAAGAAAACATAGGCATAAATCTTCATGACCTTCATTTTGTTTCTTTCTTTTTTTTT +TTTTTTTTTTTTGAGACAGAATCTTACTCTGTCGCCTAGGCTGGAGTGCAGTGGTATGAT +CTCAGCTCACTGCCAACTCCCCTGCCTCCTGGATTCATGCGATTCTCCTGCCTCAGCCTC +CCGAGAAGTTGGGATTACAGGCGTGTGCCACCACACCCGGCTAAGTTTTATATTTTTACT +AGAGATGGGGTTTTGCCATGTTGGCCAGGCTGGTCTCGAACTCCTGATCTCAGGTGATCC +ACCCACCTTGGCCTCCCAAAGAGCTGGGATTACAGGCATGAGCCGCCGCACCTACCCAAT +GGTTTCTTCAATAAGATACAAAAGCAGACACAACAAAAGAAAAAAATAGATAAACTGGAT +TTCACCAAAATTAAAAGCTTTTGTGCTTCAAAGGATACCATGAAGAAAGTGAAAAAAGAC +CGGATGCAGTGGCTCACGTCTCTAATCCCAGCACTTTGGGAAGCCAAGGTAGGCAGATCA +CCTGAGGTCAGGAGTTTAAGACCAGCCTGACCAGCATGGTGAAACCCTGTCTCTACTAAA +AAACACAAAAATTAGCCAGGTGTGGTGGCAGGTGCCTGTAATCCCAGCTACTCAAAGGCT +GAGACAGGAGAATGGCTTGAACTCGGGAGGCGAAGGTTGCAGTGAGCTGAGATCGTGCCA +CTGCACTCCAGCCTGGTCAACAGAGCAAGACTCTGTCTGAAATAAAATAAAATAAAATAC +AAGGAAGTGAAAAGACAAGCCACAGCATGGGAAAAATATTTGCAAAGACATATCTGACAA +GGAACTTTTATTTAGAATATGTCAAAAACTCTTAAAACCAAACAATAAAAAGAAAAATAA +CCCACTTTAGCCTGTAATACCAGCACTTTGGGAGGTTGAGGTGGGAGGATAGCTTGAGCC +CAGGAGTTTGAGGCTCTGGTGAGTCGTGTTCGTGCCACTGTACTCCAGTCTGGGTGACAG +AGCAAGACCTTTCTCAAAAAACGAAAGAAAGATAGAAAGAAAAAAGTAAAATAACCCAGT +TTAAGCATGGGATAAAGAATTTGAACAGACATATCTCCAGAGAAGATGTACCAACAGCAA +AGGTGCCTAGGAACATCTGCTCCATATCATTAGCTATTGGAAATGCAAATGAAAACCACA +CTGAGATACCTCTTCACACCCACTCCAATGGCTGAAATGAAAAGGACAATAACAACTGTT +GATGAAGATGTGGAAACACTGGAACCCTCACATACTGTTGCTGGGGAGGTAAAGTGAGGT +GGCCAATTTGGAAAACAGCCTGGCAGTTCGTCAAAAGGTTAAATGTGGAGTTCCCATACG +ACTGAGTAATTGCATTCCTAGGCAAATACCCACCCAAGAGAGTTAAAATCATGTGTCTAC +ATAAAAATTTATATGTGAATATTCACAGAAGAATTAGTTATAATGGCCAAAGAGTGAAAA +CAGCCCAAATGTCCAGCAACTGATGAATGGATAAAGAATATGTGGTATATCCATGCCGTG +AAATATTATTCAGCCATCAAAAGAAGCACTGATACTACAACATGGATGAACCTTGAACAC +ATGAAGCTAAGTAAAAGAAGTCAGTCACAAAAGATCACACACTGCATGATTCCACTTATA +TGAAATGTCCAGGATAAGCAAATCTATAGAGATAGAAAATAGATTCATGGTTGCCTAGGG +CTGCCGGGGGATGGAGGGAGTTTGGGAAAAATAAGAAGTTACTGCTAATGGGTATGAGAT +TTTCTTCTGGGATAACACAAATATTTTAAATTGATTGTATTGATGGTTTCCAACTCTGTG +AATATATTACAACCATTGACTTGTACGCTTTGAATAGGTGAATTTTATGATATGTAAGTT +ATATCTCAATAAAACTGTCATTAAAAAATACCCTAGCAGGATTAGATACCCTCAAAGGAT +TGAAACAGAATTCTGGGTAATCGTTAGAAAAATTCTAGTGTAAAATCAATCTGTTGAGTT +ATCCCATGTAGCTAAAATTAAAAGCATATCTTTATTCAGTAAAGAATTTCAGTAGCTTAA +GCTTTTTTCAGTTCTTTAGTCCTTTTTTCAGTTCTTTAGTCAGAGACCAGTTCTTTGCTC +TGAAAACCAGATACAGGAAATCAACCAGAATGTGTAAAAACAATAGCAAAAACTACACAA +TTAAACTTCTTCTTCTTATTATTATTATTATTATTTTGAGATGGAGTCTCTTTCTGTCAC +CCAGGCTGGAGTGCAGTGGTACGATCTAGGCTCACTGCAACTTCTGCCTTCTGAGTTCAA +GCTATTCTCCTGCCTCAGCCTCCTGAGTAGCCAGGACTACAGGTGTGCGCCACTACGCCC +GGCTATTTTTTTTTTTTGTATTTTTTAGTACAGATGGGGTTTCGCCATGTTGGCAAGGCT +GCTCTCGAACTCCTGACCTCAGGTGGTCTGCCCACCTCGGCCTCCCAAAGTGCTGGGATT +ACAGGCATGAGCCACCACACCTGGGCTAAACTTATGTTGTTAATGTAGATTAATGTCCCA +TTTCAGTCAAAAGAGAAGCTACCATGTTCCTGGGACTGTCAGTTGCCTTATACACACGAT +CACATCACAGCTCTATAAACCTCTTTTACAGATGAGTATACTGAGGCTTAGAGAATTTAC +ATAGCACAGACTCTTTGTGATGCTCTCCAAATTCACATTGCCTAGAATGTCAAAACCTTA +ATTCCATGATTGTCATAATTATTATTTTCACAAAACAGTACAATTGTTTAACTTGGACTG +TCTGATTTGATGGTGGTGAGTGTGGAGTTCCTCTTGAGAAACTCCTGATTATTTCAGAAT +AAGTCTGAATGTGATGTTATTTGGGAAGATCACTCTCTCTCTTGTCTTTCCCTCAAGTGT +GCATTAAACTGCTGCTTGTATTTGTCTATTTAACATTATATATATATATATGTTATATAT +ATATATTTATATATATATGTTATATATATATATTTATATATATATGTTATATATATAAAA +TATGTAATTTTTTTGAGGGTCTCACTCTGTCTCCCAGGCTGGAGTGCAGCGGTGCAATCA +TGACTCACTGCAGTTCGAACTCCTGCACTCAAGCGATTCTCCTGCTTCAGCCCTCCAAGT +AGTTACGACTACAAGCGCACACCACCATGCCAGGATAATTTTTGTATTTTTTGTAGAGAG +AAGATTTCGTCATATTGCCCAGGCTGGTCTCGAACTCCTAAGCTCAAGTGATAAACCCGC +GTTGGCCTCCCAAAGTGCTGAGATTACAGGCATGAGCCACCATGCCTGGCCTCATTTAAA +TTTTATATCATACCAAATATTATGTTTATATCTCTGTCTCCACCACAGAGATGGCCAGGT +GCAAGTCTCATACCTCCGATCTGAATGTAGATTAGACAATAGGTCTTTATTTTATCGAGC +TTGGTTTTGCCAGAATTCATCCTAGTATCCAGCACACAGAGGAGGTCCTCGTGCTTTAAG +GAAAGAGGGTTTCTGTTTTTGTAAAAGGGAATTCCATTTGAACCTATATTTTGAAGGTAA +AAAATGCAATGGAGAACATCACAAGGAAACTGAATTAGGCTCCTCTTGATTCTGATCTGA +GGCTGCTGATAATTCAGAATTTTGAAGGTGATTATTCTCAGTCTTTACCCTTGGGCCTTT +GTTCTTTTAACTATTATTGAAGTCTCATCTTTTAAAATTAATGACCCGGTATGACATTTC +AGAGCAGCTAAAATTGATTTGTCTATTTACTTACCTCTTTTAAAAGTAAAATAAAATTGC +ATTTGTGTGTAAAATCCCCCAGCACCAATGAAAATTGCGATTCTACATTTGCTGAGAAAT +ATCTTTATTTGTCCTCTGGGAGATCTTAAACTTTAGTTGCCTTCTATTAAACTTTTATGA +GAACAAAACTAGCAAATGACTTTTTCCCCAAACAGGTACTTTTGGTTGTTTCAAAGAAAG +AATACATTCTTGAAACAGAACTTGTTCTTTTAAACAAATTACTCAGTGTCACTTACAATG +AAAAGTGAGGGTGGGGAGGGGTGTGAATAAATTGCACAATATTAAAATTAGGTCATATTT +ATGTTTTTTCTGACTTGTCTAAATATTGCCTCAAATATCTTCCCCAGGAGGCCTAAAGTG +CTATAATTTAAGTTTTTTGCAGAGACAGAGTTACACTATGTTACCCAGGTTAGTCTCAAA +CTCCTGGGCTCAAATGATCCTCCTGCTTCAGCCTCCTTAAATGCTAGGATTACAGGTGTG +AGCCACTGTGCCCAGCCTAACCCATATTTTTATGGAAAGCATTATTTTCCCTTCACTGTC +CTTTTTTATTTATTTTTGAGTTGGAATCTTGCTAGGTTGCTGAGGCTGGAGTGCAGTAGT +ACAATCATGGCTCACTGCGGCCTCAATCTCCTGGGCTCAAGTGACCCTCCCACCTTAGCC +TCCCAAGGAGCTGGGACTACAGGCTTGTGCCACCGCACTTCGCTGCTTTTTTTAAAAAAA +TCTATTTTTAGTAGAGACAAGGTCTGGCCATGTTCCTGGTGCTGGTCTCTAATTCCTTAG +CTCAAGTGATCCTCCAACTTTGGCCTCCCAAAGTGCTGGGATTGCAGGTGTGAGCCACTG +CACCCAGCCTAATTCCTATTTTTATGGAAAGCATTATTCTTCCTTCTCTGTCCTATTTTA +AAATATAAGTGCACTGGGAACAGTGATATGTTAGGGAAGGCTGATGTGGAGGGGACAGTC +CTAGAGTAATTGCTGGTGGGCAGTGGCGAACTCCATCAGTAAGGTCTCACCCTGCTATTT +GATGGGTCTACCTCTACTCGGCTGTGGGTTTTCATTTGAAATCGAACTACCTGTGGCTCA +TGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGCAGGCGGATCACCTGAGGTCAGTAGTT +GCAGACCAGCCTGGCCAACATGGTGAAACCTCGTCTCTACTAAAAATACAAAAATTAGTG +GGGCGTGTTGGTGGGCACCTGTAATTCCAGCTACTCTGGAGGCTGATGCAGGAGAAACGC +TTAAACTCGGGAGGCAGAGTTTGCAGTGAGCTGAGATTGCACCACTGCACTCCAGCCTGG +GCGACAGAGTGAAACTCCATCTTAAAAAAAAAAAAAAGTAAAATAAAAAATTAAATGAAT +AAATGAAATTGAACTACCTGCCTAAAACCCAGAAAGGTGGGTGGGGCTGGGGGGAATAGA +AAGAGTATTCAGCATTGAGGCTGATGCAGTTAATGCTAAGTCGAGCCATCAATTCTTTGT +GACATCATTTTCCTTGATAGTCCTGTTATCTTTTCATCCACTAAGTTACTAAAGCACAGG +CTCGGAGGTTGTGGTAGGCAGCCCTGTGGACCCATTTTAGACTTCTGACCTCCAGGACTG +TGAGATGATACACCAATGTGGTTTTAAGCCTTGAAGTCTGTGGTAATTTGTCACAGCAGC +CATAGGAAATGAATGCAGGGGTCTTTCCTCATGTCTCATTCCACTCCACCCTCACCGCCT +TCCAGTTTGACTCTAGCATTCACTCAGTTCTCTTCCCCACTGTGGCAACGTGCTGGCCCA +CCCTCCTGGGCATAACTGCCCCAGCCTCTTGCTTGGGCTCTCCAACCCATTTTCATGCTG +CAGTCTGCCTGATGGCAGGAAACCACAGATAGGTTTATGAAAACCCCTGCTTTGAAAAAC +CTTTAATATCTTGCTATTGCCATTAAAATTAAATCCAGATGTCATCCCGAGAAGCACCCA +GCACTGCATGCTCTAGTCCCTGCCGTCTTCTCCAGCCTTATCAGTGTTCAATGGTGGTTT +TGAGGCAGAATATCTGGCTCCAAATTCTGCTTGTGCCACTTACTCTCTGTAGGACCTTAG +ACAAATAAACCTCTCTATGCCTCAGTTTCCTCTTCTATACAGTACCTAATTGGATGTTTG +TGAAGATTAAACAAATTAATCAAAATAAAATGCCTGGCACTATTCTAAACACAATACCAT +TGGTAGGTAGCCTTATTCTTACTGTATTACCCATGCCACTGGCAAATTGTGAGCACTGAA +ACCTCTGGTGAATGAATGAATGCATAAATGAATGGAAGTAATGTTACATTCACAACTTCT +CTGTGTGTACCATTGCTTCTCTCTCTAGTGTGCAGAATGAATCAGTGTCACAGACACATA +GTCAAAATTTAGATAAGCCAAGAGACAATTGAACACTGGGGAGCCACATTTTGGCTACTA +GATGTACAAAGAACGGATCTAAGATCTGGTTTACTATGAAGAAAGATGGAAGCTCTTTGA +GGCAATTGCTAAACTCTTGAGGGCATCTCTAGTAAGCACTGAAGGACACTCGAACCAGTG +TTCAGACCTAACATTGGTGTATCTAAGAAATATTGATATATACTTCTAAGCTGTTCTTAT +CTTACTTTTCTGATTTTTTTTTTTTTTTTTTGAGACAGAGTCTCACTCTATTGCCCAGGC +TGGAGTGCAGTGGTGGGATCTTGGCTCACTGCAACCTCCACCTCCCACGTTTGAGCGACT +CTCTTGCTTCAGCCTCCCGAGTAGCTGGGATTTCAGTCATGTGCCATCAGGCCCAGATAG +TTTTTGTATTATTATTCTTTTTTTTAGTAGAAACAGAGTTTCACCAAGTTGGCCAGGCTG +GTCTCAAACTCCTGGCCTCAAGTGATCTGCATGTCTCAGCCTCCCAAATTGAGCCACCAC +TCCTGGCCTCCTGAATTTATTTAATAATGTGTAGCCTTCTAACTGAAGAGTAATATTCAT +GACTGTGGTGTTTCCACAGAAAGGTATAAACTTGCCAGATGCTAACAGCACTCCCTGTCT +ATGGTATTTACTTTTGGGTATGTTCTACAGAGAGAGAATATTTCCAGTAGGATTTCTGTG +CAGTAAATGTCAGTTCCTTTGCAGATAAAGTTTTATTTCCTTTAGGATGGGTCTATATTA +AGAGATAATAGAAAACGTCTTGTGTGGGAGAGAGGAGTTTGAGACCGCTTTGGTTGTCTT +CACCATGTCCTAAGGGGTTGAACTGGGCATTCTGTCCAGAGTTCTTTCACCCTTTAGTTT +AATGACCTCAAAGTTCTGTCCTGCTTTCATAGGTACATACTTCAATAATTGAATTTTCAT +GTTCTTAATTTTTTTTGCTAATATATAAAAATGTAATTACTTTTGGGGGGAGGCTTATTG +AGGTATAATTTATAAGCAGGAAAGTTTACCTTTTAAATGTACTTGGTATGGTTTGGGTGT +GTGTCCCCATTCAAATCTCTCATCAAATTGTAATCTCCAATATTGGAGGTGGGGCCTGGT +GGGAAGTGACTGGATCATGGGGGTGGATTTCCCCATCAGTGCTGTTCTTCTCATAGTGAG +TTGCAGTGAGATCTGGCAATTTAAAAGTGTGCAGTACCTCCCCACCACTCCTTTTTCCCA +CTCTGGCCATGTAAGAGGAGCCTACTTCCCCTTCACCTTCCACCATGTCTGCAAGTTTCC +TGAGGCGTCCCCAACCATGAGCCGACCGAACGAACCATGAGCCAATTAAACCTCTTTTTT +TTTTTTTTTTGAGACGGAGTGTTGCTCTGTCACCCAGGCTGGAGTGCAGTGGCGCGATCT +CGGCGATCTCGGCTCACTGCAAACTCCGCCTCCCGGGTTCACCCCATTCTCCTGCCTCAG +CCTCCCGAGCAGCTGCGATTACAGGCGCCCGCCACCACACCCGACTATTTTTTTGTATTT +TTAGTAGAGACGGGGTTTCACCGTGTTAGCCAAGATGGTCTCGATCTCCTGACCTCGTGA +TCCACCCGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCTTGAGCCACCGCACCTGGCC +TTAAACCTCTTTTCTTTATAAATTACCCAGTCGCAAGTATTTCTTTATAGCAGTGTGAGA +ATGGACTAATACAATACTGTTCTATGCATTATGGCAAATACAGAGTTATTTAATCACCAC +TATAATCAAAACATAGAACAAATCTATCACCTTTCTCTCCCCTCAAAATTCTCTCATGCG +CTTTCGTAGTAAATACCTCATCCCATCTTGAGCCCCCTGGCAAGAACTGATCATTTTTTC +TCTCTACAGTTTTGCCTTTTTTTTTTTTTGAGATGGATCCTTGCCCTGTTGCCCAGGCTG +GAGTGCAATGGTGTCATCTCAGCTCATTGCAACCCCTGCCTCCCTGGTTCAATTGATTCT +CCTGCCTCAGCCTCCCGAGTAGCTGGGATTATAGGTGCCCACCACCACGCCCAGCTAATT +TTTGTATTTTTCATAGAGATGGGTTTTCACCATGTTGGCCAGGCTGGTCTTGAACTCCTG +GCCTCGTGATCTGCCCACCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACTG +TGCCCGACCTATAGTTTTGCCTTTTCTGGATGTCATATGAATGGAGTCTATTATATGCAG +CCTCTTGAAAGGGGCTTTCTTCACTTGAGAGTCAGATGTGTTGCTGTGTGTATCAGCAGT +TTGTTCTTTCATCTTGCTCAGTAGTATTCCATTGTATGGATATGCTCCAGGTTGCTTATC +CATTCATCTGCTGGAAGAAATCTGGGTTATTTCCAGTTTGGAATAATTATAAATAAAGTG +ACTACACCACTCACATACACGTTTTAGTGTGAACATAAGTTTTTATTTCTCTCAGGTAAA +TATCTAGGAGTGGGACTGCTGGGCCATAAGCTATATGTATAGCTAGTCTTATCAGACACC +AGTAAACTGTTTACCAAAGTGGCTGGGCCAGTTTGTATTCCCACCCACGGTGTATGAGAG +TTGCAGTTGCTCTTCATTCTCATCAGCATTTGATATTTCCAGGTGTTTCAATTTTAGACA +TTCTAATGGGTATGTAAAGGTATCTCATTGTTGGCCAGGCGTGGTGGCTCGTGCCTGTAA +TCCCAGCACTTTGGGAGGCTGAGGCGGCAGATCACAAGGTCAGAAGTTCAAGACCAGCCT +GGCCAATATAGTGAAACCCCATCTCTACTAAAAATACAAAAATTAGCCAGGTGTGGTGGC +ACGTGCCTGTAATCCCAGCTACTCAGAAGGCTCAGGCAGCAGACTGCTTGAACCTGGCAG +GCATAGGTTGCAGTAGGCCGAGACTATGCCATTGCACTCCAGCCTAGGGGAAAGAGTGAG +ACTCCGTCTTAAAAAAACAAAAAGGTATCTCATTGTTGTATAATTTGTATTTCCCTAGTG +ATTTTATATATATATATATATAATATTTTAGACAATGTCTCACTCTGTTGTCCAGGCTGG +AATGCAGTGGTGCAATCACAGCTCAATGCAGCCTGGACCTCCTGGGCTCAAAGTGTTTCT +CCCACTTCAGCCTCCTGAGTAACTGGGAATACAGGCACGCAACAGCAACCCCGGCTATTA +AAAAATAAATTATAGAGAAAGGGTCTCATTATATTGCCCAGGCTGGGCTCAAACTCCTGG +GCTCAAATGATCCTCCCACCTTAACCTCCCAAAGTGCTGGGATTACAGGCAAGGGCCACC +ATATCTGGCCTCTTAGCGATTGATGAGTATCTTTATATATGTTTGGTTGCTAACCATATA +GCTTCTCTTATTACGCTTATTTCTTCATATGTGATATATATTTTTATGTACTATATTTTT +GCTGATAATATATAAAAATAGAATTGATTTATGTATATTAACCTGGTATCCTGAGACCTT +CCTAAATTTACTTGTTAGTTCTAGTAGTAGTTTTGTCAGTTCCTATGATTTCTGTATAAA +CCACCATCATGTCATCTGAAAATAGGGACAATTTTACTTCCTTTTGAATTGTTACACTTT +CCATATCTTTTTCTTGCTTTGTTAATGGTTATAAACTACAGACAAATGTTAAGAAGTGGT +AAGATGAGGCATCCTTGCCTTCTTCCTGATATAAGGGGGAGAGTGTTCAATATATTACCA +CTAAGTCTGATATTGGCTATGGATTTTTCATGAATGACCTTTACTATATTGAGGAAGTCC +CTTCTAATTTTTTTGGCAGTTTTTATGAGTAGGGATTGAATTTTAAGTGGTCTTTCTGCA +TCTATTGTGATGACAACAGTTTTTCTTTTTCAGTTAATATGGTGAATTACGTTGATTGGT +TTTAGATCATTAAATACAACTTGCATTCCTTGCACTGGGGACAAACCCAAATTGATCATG +ATGTATTATCTTTCTATATACTGTTGGATTCAATTTCCTAACATTTTATTAAAGTTGTTT +TTGTTTCTATGGTCATGTGGTATATTAAGCTGTATATTAATTTTTTTGTAGTGTTGATTT +TATGTTATGCGGGTTATGCTGGCCTCAAAATGAGAGGAAAACTGTTTCCTCCTCTATTTT +CTAAACAAACTTTGCACAAGACTGGAGTTCTTCCTTCCTTATGCGTTTGATAAATTTGAC +CACTGAAACCATCTGGGCCTGGAATTATCTTTGTGAGAAGTCTGTTGAACAACAATTCAA +TTTCTTTAAAAATGAAAAGCTATTCAGATTTTTAAATTCTACCCTATTTCAGTTCTGATA +AATTGTCTTTTTTATAGAATTGGTGCGTTGCATCTACATTGTCAAATTAATTGGCATAAA +ATTGTTTATAATACCTCCTCATATATATCTACATGATCTGTAGTAATACCCCTATTTTTG +TTTTATTGTCTTGGCCAGTACAGGAGGAATTCTCTTACTCTCTCTCTTTCTCCTCTCTCT +CTCTCTCTCTCTCTCTCCAGTTGACCTTCCATGGCCATGGGTTCTCCATCAGTGGATTCA +ACCAGCCACAGGTCAAAATATTAAATAAGGCTGGGGCACCATGGCGCACGTCTGTAATCC +CAGCACTTCGGGAGGCCTAGGTGGGTGGGTCACCTGAGGTCAGCAGTTCAAGACCAGCCT +GGCCAACATGGTGAAACCCCGTCTCTACTAAAAATACAAAAATTAGCCGGGCGTGGAGGC +GGGTGCCTGTAATCCCAGCTACTTGGGAGGATGAGGCAGGAGAATCGCTTGAACCTGGAA +AGCAGAGGTTGCAGTGAGCTGAGATCGTGCCACTGCACTCCAGCCTGGGCGCCAGAGTGA +AACTCCATCTCAAAAAAAAAAAAAAAAATTAAATAGCAATTAAAAAACACAAAGAAGCGA +TATAGCATAACAACTGTTTACACAGCATTTATATCAGGTATTATAAGTAATCTAGAAATG +ATTTGTACTACAGAATGTGTATAGTCTATATGTAAATATTATGCCATTTTATGTAAAGAA +CTTGAACACTGGCTGGGGTGATGTTCTGGAACCAATACCCCATGGATACGGAAGGACAAC +TGTATATACACCTGCATATATAAACTATATATTTACAAGGCCAGAAATTGTTGAGGGTGC +CCAGCACAGTAACTGGCACGAAGTAAGTCATCATAATAGTTGTATTAGCGTTGCCTTCAT +AGGTGGTGATTTGGAGAATCTATTCTAGGTGGGTACAGCAATGGAGGCTTTGGTCCAGTT +TGTCTAGGGTCATGGTGGTGAGAAATAGCAGACAAGCCTGAAAGGATGATTTGGGGCTTT +CCTTGCCCCAAAGAGAGAGAGAGACAGAAAATCCTTGCACCGGATGATATCAATGCTGTG +CCTCTGAATGTCCATTTGGAAAGCCAGTCCTGTGCTTCCAAAAACAGGATATTCAACACC +TTGAAGAGGTGTGGTAATTGCACATCTTACTTTTTACGTTTTAGGAAGTCTACAGAGAGT +GGGGCTGAAAAGTTTGGGAAGAACAGGTAGGCATGTGGGGAGGGCAAAAGAACAGAAATA +ACATGCACAAGCATTTTTCTAGGAAAATTTTAGGGAAAGCTAAGTGATGTAAAGTTACAC +TTAAAAGACTACACATTTTCGGCCGGGCGCAGTGGCCGAATCCCGGCAAAAGTAATCCCG +GCACTTTTGGGGGCCGAGGCCTGGGGAACACGAGGTCAGGAGTTCGAGACCAGTTGGCCA +ACACGGCAAAACCCCGTCTCTACTAAAAATTAGCCGGGCGTGGTGGCAGACACCTGTAAT +CCCAGCTACTCGGGAGGCCGAGGCAGGAGCATCGCTTGAAACCGGAAGGCGGAGGTTGCA +GCGAGCCCAGATCGCGCCACCGCACTCCAGCCTGGGCGACAAGAGCGAAACTCCGTCTCA +AAAACAAAACAAAACAAAAACTACACATTTTCGCACTTTAAGGGCTCAACGGCTGTATTC +CCACTCCTTTGCCACTCTCTTTGCTCTTTTCCGCTCTAGAAAGAATTAATGAACTGGATC +AAATCTAAGTTCTCCACGTTACAGATGGGAAGCCTCCGGGCCAAGGAGGCCAATGGTTAC +ACAAACCAGGTAAGAAAATAAAATATGCCCAGTAAGTTCATAGGACCGGCGGGCTTAGAT +TTCGAATGCGCGTGACTCTGTCAACTGTGGACTTAACCCTATGCAGAGATTAGAGGAGAG +AATAGTCAAACACGGATAAGTTAACATTTACCGAACAGTCCGTCCTACCCTGGGGTAGGT +TTTATTAACAGTCTCGTTTTGCAAAGGAAGACAGCTGCCAGTTGT diff --git a/test/csq/ENST00000256452/ENST00000256452.fa.fai b/test/csq/ENST00000256452/ENST00000256452.fa.fai new file mode 100644 index 0000000..e788ec1 --- /dev/null +++ b/test/csq/ENST00000256452/ENST00000256452.fa.fai @@ -0,0 +1 @@ +3 57105 21 60 61 diff --git a/test/csq/ENST00000256452/ENST00000256452.gff b/test/csq/ENST00000256452/ENST00000256452.gff new file mode 100644 index 0000000..c4f53c6 --- /dev/null +++ b/test/csq/ENST00000256452/ENST00000256452.gff @@ -0,0 +1,30 @@ +3 ensembl_havana gene 21 57085 . - . ID=gene:ENSG00000091181;Name=IL5RA;biotype=protein_coding;description=interleukin 5 receptor%2C alpha [Source:HGNC Symbol%3BAcc:6017];gene_id=ENSG00000091181;logic_name=ensembl_havana_gene;version=15 +3 ensembl_havana transcript 209 40452 . - . ID=transcript:ENST00000256452;Parent=gene:ENSG00000091181;Name=IL5RA-004;biotype=protein_coding;ccdsid=CCDS2559.1;havana_transcript=OTTHUMT00000206523;havana_version=1;tag=basic;transcript_id=ENST00000256452;version=3 +3 ensembl_havana three_prime_UTR 209 696 . - . Parent=transcript:ENST00000256452 +3 ensembl_havana exon 209 783 . - . Parent=transcript:ENST00000256452;Name=ENSE00001908764;constitutive=0;ensembl_end_phase=-1;ensembl_phase=0;exon_id=ENSE00001908764;rank=13;version=1 +3 ensembl_havana CDS 697 783 . - 0 ID=CDS:ENSP00000256452;Parent=transcript:ENST00000256452;protein_id=ENSP00000256452 +3 ensembl_havana exon 5254 5338 . - . Parent=transcript:ENST00000256452;Name=ENSE00000912357;constitutive=0;ensembl_end_phase=0;ensembl_phase=2;exon_id=ENSE00000912357;rank=12;version=1 +3 ensembl_havana CDS 5254 5338 . - 1 ID=CDS:ENSP00000256452;Parent=transcript:ENST00000256452;protein_id=ENSP00000256452 +3 ensembl_havana exon 7003 7099 . - . Parent=transcript:ENST00000256452;Name=ENSE00000912359;constitutive=0;ensembl_end_phase=2;ensembl_phase=1;exon_id=ENSE00000912359;rank=11;version=1 +3 ensembl_havana CDS 7003 7099 . - 2 ID=CDS:ENSP00000256452;Parent=transcript:ENST00000256452;protein_id=ENSP00000256452 +3 ensembl_havana exon 22696 22834 . - . Parent=transcript:ENST00000256452;Name=ENSE00001657506;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00001657506;rank=10;version=1 +3 ensembl_havana CDS 22696 22834 . - 0 ID=CDS:ENSP00000256452;Parent=transcript:ENST00000256452;protein_id=ENSP00000256452 +3 ensembl_havana exon 25771 25916 . - . Parent=transcript:ENST00000256452;Name=ENSE00001619473;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00001619473;rank=9;version=1 +3 ensembl_havana CDS 25771 25916 . - 2 ID=CDS:ENSP00000256452;Parent=transcript:ENST00000256452;protein_id=ENSP00000256452 +3 ensembl_havana exon 28342 28529 . - . Parent=transcript:ENST00000256452;Name=ENSE00001733184;constitutive=0;ensembl_end_phase=1;ensembl_phase=2;exon_id=ENSE00001733184;rank=8;version=1 +3 ensembl_havana CDS 28342 28529 . - 1 ID=CDS:ENSP00000256452;Parent=transcript:ENST00000256452;protein_id=ENSP00000256452 +3 ensembl_havana exon 28609 28762 . - . Parent=transcript:ENST00000256452;Name=ENSE00001634426;constitutive=0;ensembl_end_phase=2;ensembl_phase=1;exon_id=ENSE00001634426;rank=7;version=1 +3 ensembl_havana CDS 28609 28762 . - 2 ID=CDS:ENSP00000256452;Parent=transcript:ENST00000256452;protein_id=ENSP00000256452 +3 ensembl_havana exon 32164 32302 . - . Parent=transcript:ENST00000256452;Name=ENSE00001730405;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00001730405;rank=6;version=1 +3 ensembl_havana CDS 32164 32302 . - 0 ID=CDS:ENSP00000256452;Parent=transcript:ENST00000256452;protein_id=ENSP00000256452 +3 ensembl_havana exon 33147 33292 . - . Parent=transcript:ENST00000256452;Name=ENSE00001624596;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00001624596;rank=5;version=1 +3 ensembl_havana CDS 33147 33292 . - 2 ID=CDS:ENSP00000256452;Parent=transcript:ENST00000256452;protein_id=ENSP00000256452 +3 ensembl_havana CDS 35375 35456 . - 0 ID=CDS:ENSP00000256452;Parent=transcript:ENST00000256452;protein_id=ENSP00000256452 +3 ensembl_havana exon 35375 35459 . - . Parent=transcript:ENST00000256452;Name=ENSE00002726718;constitutive=0;ensembl_end_phase=1;ensembl_phase=-1;exon_id=ENSE00002726718;rank=4;version=1 +3 ensembl_havana five_prime_UTR 35457 35459 . - . Parent=transcript:ENST00000256452 +3 ensembl_havana exon 35940 36008 . - . Parent=transcript:ENST00000256452;Name=ENSE00001322495;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001322495;rank=3;version=2 +3 ensembl_havana five_prime_UTR 35940 36008 . - . Parent=transcript:ENST00000256452 +3 ensembl_havana exon 39022 39163 . - . Parent=transcript:ENST00000256452;Name=ENSE00000997127;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00000997127;rank=2;version=1 +3 ensembl_havana five_prime_UTR 39022 39163 . - . Parent=transcript:ENST00000256452 +3 ensembl_havana exon 40417 40452 . - . Parent=transcript:ENST00000256452;Name=ENSE00001898297;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001898297;rank=1;version=1 +3 ensembl_havana five_prime_UTR 40417 40452 . - . Parent=transcript:ENST00000256452 diff --git a/test/csq/ENST00000256452/intron.txt b/test/csq/ENST00000256452/intron.txt new file mode 100644 index 0000000..39d0301 --- /dev/null +++ b/test/csq/ENST00000256452/intron.txt @@ -0,0 +1,3 @@ +35931 A AAAC intron|IL5RA||protein_coding +35931 A AAAC intron|IL5RA||protein_coding + diff --git a/test/csq/ENST00000256452/intron.vcf b/test/csq/ENST00000256452/intron.vcf new file mode 100644 index 0000000..502c8a3 --- /dev/null +++ b/test/csq/ENST00000256452/intron.vcf @@ -0,0 +1,7 @@ +##fileformat=VCFv4.2 +##contig= +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO +3 35931 . A AAAC . . EXP=intron|IL5RA||protein_coding;type=ENST00000256452:3147143-A-AAAC diff --git a/test/csq/ENST00000294661/ENST00000294661.fa b/test/csq/ENST00000294661/ENST00000294661.fa new file mode 100644 index 0000000..650ef6b --- /dev/null +++ b/test/csq/ENST00000294661/ENST00000294661.fa @@ -0,0 +1,163 @@ +>1 1:85715639-85725355 +GCAAGAAACAGGTTTAATTGGACTTACAGTTCCACATGGCTGAGGAAGCCTCACAATCAT +GGCAGAAGGCAAGAGGAGCAAGACACATCTTATGTGGAGGGCAGCAGGCAGAGAGCTTGT +GCAGGGCAACTCCCTGCACTGATGGTTTTTAAAACCATCAGATCTCGTAAGACTCATTCA +CTATCATAAGAACAGCACCGGAAAGACCCACCCCCATAATTCAGTCACCACCCATGACAC +GTGGGAATTGTGGGAATTACAATTCAAGTGAGATTTGGTTGGGGACACAGCCAAACCAGA +TCAGGATCTCAACATGTTGCCCAGGCTTAACTTAAAGTGCAGGAAACAATCAGAAGTATC +AAGTGACTCGATTCTCTAAAATGAAAGATACTTGGACAGATGATTTTTCTTATGTATATG +GATTTTTAAGACTTTTCCCCACTAGGTTTCCACTAGCTCAACCAAACTTCACCTCAGTAC +CCACATGGACACTTGTGCAAACACGTTCCCAGGACATCTCTAAAGGGGAAAATAATCTAT +TCTCTAATGTGATGATGAATGTAGAGTGATATGACAGTCCGTTTTCCAACCAGGAGATAC +AAATGGCTGAGTCAGACTTGCTCCAAAATATTTAGCCTCTTCCCTAAGTCCTGTCTTCCT +CCTCATACAACATACTCTGCACATCTCCCAGGAAAGAGAGAAAAAAGTTTGCTTTCATGC +TAACTTAAGAACCTTGCAATATTTCAGTAACTTCTGAGATATTTGCTCCACCAACACATG +CATCCAAATTTTAGATTTCTCCAGAGCTTGGGAATCACAACTTCACAAATATAACTTGAT +TTGGTTGTGTTTGGTGTCATGTACATACTATGGTCTTGCTTTGTCACTTGATGCCACTCC +TTAGTATATGATACCACAGATTTCCAAATTCATTACAAAGACTACAATCTTAAAAAAACA +TATTCTTGCTTTAGCAATTACTTCAATTTTGGGATTCATATATTTGCAAACCTGGAGGAT +GGGCAGCTATAGAATTGGTTTTTCTAAACTCGATGATATACTGGAAGCCATCATGCTGTT +ATGGACCTTCATTCCACAAAGCACCATGGCTGATGCAATCACTCTTAATGACTTTTATGA +ATTTTAATCTACTTGATACACATGCCTAGGTAAACAAATCTCGCGTAATTGTTCAAATTT +TATCTTCCACAATGGGGAAAAACAGATTTAAAAAAAAATACTTAGATTATGTCTTTTTCT +TTCTAAATTATTTTTTGTAAAGATGAGGTCTTATCATGTTGTCTAGGCTGGTCTCCAACT +CTTGGCCTCAAGCTATCCTCCCACCTTGGCCTCCCAAAGTGCTGGGATTACAAGCATAAG +CCACCATGCTTGGCTGTCTTGTTCTTATACACTGAATGTGCACTGTTCTGTAATTCTTAT +CTCTTAAGGGCTTCAGATTCATGGAAAGATTGATGCAGAGTGTAACCTTTTTATTGTTCA +AAATGCTACAAATAACTGCATTTTGGAACTCAACGATCACACCTTCCCAACTACTTCTTG +TTCATTTTATTATTACTATACGCAAAGCATTAAAATAGAAGCTGGGTAGAGAAAACATGT +AGAAGTAGGGTTACCAGATAAAAGATGTTCAGTTAAATTTGAATTTCAGATAAACACATT +TTTTGTATATGTCCTGAATATTAAATATACTAAAACATTATTTATCTGAAATTCAAATTT +AACTGAATGTCCTGTAAACTTACAATTTAATAAAGAAATTAATGAATAACCATAAAGCAC +AGATGACAAGTACAGTCATCCAATCAGGAGAGGAAAAGATCTCTACTAACGGATCTCCAG +GTACAACAGAAAAAAGTACCTGGAAGAGATGACAATTGATGTCATTCCTGAAAGATGACT +AAATTTTGACTGGTGGACAGGTGGTTTAATGTGATGATTTTGAGGTTCAAGTGTCCCAAG +TTAAATTCCAAATGAACCACTCACTAGCTGTGTAACATCAGACAAGCTACTCAAGCACTC +TTTATTATAAAATGAGAATACTAATAATACCTTGCGCTAGGTTGTTTAAGGATCAGAGAA +AATATATGCACAAAGCACCTGGAACACAGGAGGCACTCTTTAAATGGTAATACTTCTTAT +TACAACTTAAAATGTCACACGACAAATAGGGTACTTGTCACAGACAAACATTCAAATGTT +AATGTTATACAGTAATAGTAATATTGAATAAGTAATTTTATTTCCATGATCTATTTACAC +TGTACAAAGACTGTTGAAAAGCACCCTACAAGTTCACAGTACATTACAATATATTTACTT +TAAAAATATATTCCTTTATAAAAGGTTTATAAGAACATTGGCATGTCAACATGTGACAAA +ACTCTCAAAGCATGTCACCAATTCTGTGAGAGCAAGAATGCATCCAAGTGTTATCAATTT +CACAATCACAAGTCACCAGTTGAGTTTTAAATACATACATGTTTTAAATAAAAAAAGAAT +TCTATAGTGGAAAGTTCTTGAGGCAATACTTATTAGTTCATTAACGTATGCATTTTCATG +GAGATGTGGCATAATAACCCACAATATCAACTTAATCTGTCCAAAGAAACATTTCAACAA +GTTTAGCAGTACAGAAATTCTGGTCATTTGTTTCTACTTTTTCTTCTTTGCTGGTTCTCC +TGGCTCTACTTTGCGCTTTTTAGAAGTATGCTCATCTTTTTCATCATCTTTAAATAGAAA +AGGAAGAGTTTCAATCAGTAATTTTAAAAAACCCAACATGTTAAGCATTAAAATTTCACT +GGCTTTATACCAAAATTATTACCCTCATCAATTAATGTTTCTCTCAGAGTTTCCCAATAA +AAAACAAGAATTAACTTTTAGAGCTCTGATTTTTAAATGCAAGTGAAAGTGAGCAATTTT +TTTTTTCAATTGCAGCCATACAAAATTCACAAAGTAACTCTTTAGGTGCTATACTAAGGT +AGCTTAAAATAAGTGACTTTACTTCCCCCAAATCAGACTTTTGAAAAAGGCTCCCAAATA +CTCAGCAAGCTTGTCCAACCTGCCTTATTTGTTGTTGTTGTTCTGTTTTGTTTTAGGCTT +TTAGCAGCCTGAAGCCATGGTTTTTAGTTTCTGTCTCTAGTGATAAGCAGAAAAGAAGGA +TGATGAAGGGGCTTTATTGGCCCAACCAATAACAGAAACTAAGAACTCATGACTGTATTC +TCTCCCTTGGACACCACTGCATGATAGTATTTACATTGTATATATTAAAATACAATCAAT +GCTTTGTAAGAATGGAGCATATTGTTTTCTTTTTACAAAAAATAGGTATCACTCTAACGA +TGACATTATTTAAGTGGCTATCAGCTGTCCTTTTCCTTTCAATCTGCTTTCTCTCCTCCA +AAAACAACTTCTTCTGCCCCATCACCTTCTCCACCCACCCCAAATCCTTATTTTGAGGTT +AAAAAGCACTCACAAGTAGGTTTCCCCAAACCTCTATTTGGAATTTTATTCTAGTAAGTT +CTAATTCCCATCCCCGCCCTCCCCATCCCCACTCCCACGATGGCCAGAACATTTTAATGG +CAACAGAAAAATACATATCTTCCTACTTCATATTATGGAGAATTTGGAGAGGGGAGGGAG +GTTAGAGAAGAGCCTTACATTAAAACAATGTTCTTTACACCTTTCCAAAATGTTAATAGT +ATCTGTAGCCACAGAAAATTTCCAATTCATAAAAATGTTGTCAAACCTGGAAAAGTGAAC +TCTTTTATTGTATTTTAAAAAATCCAACTACATGGTTAAAAAAAAAATACAGGGTAGCAC +AGACTAGTTGCTAATTCCATCTCCCTAAGCAAATGTGTGGTATTAAGAACTCCATATAGA +CAGAGTAACATGGAAAAGATGTTATGATTTATAAAATACAAATTTATTTTGAGCACATTA +CTAATTAATTGTAGCTTTTGACTTTATTTTCTTGATCAACAGATACTCAAAAAGTTCAAC +AGGTTATCATGTGGAGATCTATAAAATATCTTGATATTGAAAGGAGCCTTCATTATTAAA +AAATGTGAGGAACTACTGACATCAAATCATAAATTCCTTGAAGGAAATATTAAAATCTTA +AGCCTTCAATTCCCTTCTGCTGACTGTACCATAATCAGAATATCTCATTTATTGATGCAG +ATAACAATCAATACCATTCATCTTCACTCCCCTTCAAGCACAGCACGGTGATGTTATTCA +TATGCTTCACAGAGCACTATGGATTTATGTAGGCAGTGGAATAAAATACAATTCAGATCA +ACTCACCCCAGGAATTTACAAATCAAAGTTTTAATCAGTAGTTCATCATGTTCATACAAA +AACACTGGCTCCACAAACCAAATAACATGGTATACCACCAAAACAAGCCAAACGTTTTGC +TTTTTTTTTTTTTTGAGATGGAGTCTTGCTCTGTTGCCCAGGATGGAGTGCAGTGGCACC +ATCTCAGCTCATTGTAATCTCCACCTCCCAGGTTCACGCCATTCTCCTGCCTCAGCCTCC +CAAGCAGCTGGGACTACAGGTGCCTGCCATCACACCCAGCTAATTTTTTGTATTTTTAGT +AGAGACGGGGTTTCACGGTGTTAACCAGGATGGTCTCTATCTCCTGACCTCGTGATCCAC +CCACCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCACCCGGCACCTTT +TGCTTTTTAACGAGTTAATTATCACTAAGCTCCTCTTTTGAGATTTTCAGTAGTGATAAT +ATAAAAATGGAAAGTACTAAGTTTACTATAATATTCACTATGCATTAGCATACATTTAGA +TGATACTGAGATATTTTTGCTTTTAATTTGCCACTTATTACAAGTAAATTAACTGAATAA +CAAAACCACAAACTACTGAAGTTAAAAAGTAACTGGCTATCAGTGATTTGAGCAGAAGTG +CTATGCCATCTAGTGTCATGACAAGGCATTGCTTTATAAACTAGAGTAGGAAAAAATCTG +AGCAATGTTCATTTATCAATTTTACTGAGCTTTTTTACTCGGTCTCATATAGTATAGATG +TACTGGTAAGGAAACAATTTTTTTATTATGGAACTCAAATCACTCAAGTAAGTTTAACTT +ATCAATAGACAAACTTTCTAAATTCTAAAAAGTGTAAACTAAAAATCACTATATTAATTA +TGCTTTTACAATTAATTATTATACATGTCAATAAAGCTACAACTAATAACTAAGCTTTGC +TTACCTACATTTTACAACCACTAAAACCAGAAGTGGCAGGGTGCGGTGGCTCACACCTGT +AATCCCAGCACTTTGGGAGGCTGAAGCGGGCGGATCACGAGGTCAGGAGATCGAGACCAC +CCTGGCCAACATGCTGAAACCCCATCTCCACTAAAAATACAAAAATTAGCTGGGCGTGGT +GGCGTGTGCCTGTAGTCCCAGCTACTTGGCAGGCTGAGGCAGGAGAATCGCTTGAACCCG +GGAGGCGGAGGTTGCAGTGAGCCGAGATCACACCACTGCACTCCAGCCTGGGCGACAGAG +CGAGACTCCATCTCAAAAAAAAAAAAAAACCCGAAGGGCTGATAAGCAGCAAGACCCAAT +GATGAGTTCTGAACCTTTCCCAGCCCTTCCTCTAAAGTAACTGGAAGACGTTAACCGGCA +ATAAAAGGCCAAAGGGCAGAATGGGGAAGCAAAATAAAAAAGTCACTTGCTAATCTAAAA +TCTGGGTAAGAGTGTAGAGTTTCTGATATATATTTTATGAATGAAAAAGAAAGGCTAAAA +AATTATGACATAATTGATTTTATAGGAATCTGAAAATCACTTCTAAAAAATGGGTCTGTT +ATTTGATTTTGCCTGTATTTGTTTTCCAATAAAGGACCATCATGTGATCAAAAAGACAGA +AATTATCTATGTGAATAGCAGTGTTACCTGCCACATATTTGGAACTCCTTCTAACTTAAC +TCAAAAGCTAAGCTAGAAAAAGATAATTCTTTCTTGCTTGCTTGCCCTGGTGTATAATCC +TGGTTTTTTCCATATAACTACAAAGATGTGAGAGCACCAGCCTATGGAAATCTAGTTTGA +GTATCAACCCTAGTATCTTTACTGCCATTCGCCCTACAGAAGAATAGCTATATCTCACTG +TTGAGAAATGGCTATTCATCAGGAGACCAAATCCCAGTTTAATAAGGCATAATTTCTATT +TAAAGGTCTGGATTTGAATGCCTACTACTCTGTCTCTTCTTTAGCTGCGTGAATGAATTT +GGGTAAAGTCCCTAATCTCAGATTGTTTTATCATCTGTAAAACAGTAATAATGAGTCATG +TAGCACTTCTGTATCAGGTTGCTCGGAGTAATAAATTAGAAAACTGTGTGAAAGTGCCTA +TTTTAGAATTTGGCATTTTCTAGTTTGTGACCTTGGACAAGTTATGTAAGCTATCATTTC +CACATTTCTCTATCTTATTTCACAAGGTGTTGTAATAAAGATTATTTAAGCAAATATATT +TTTACTAATTATGAAAAGGAATGGCCGGGCACGGTGGCTCACGCCTGTAATCCCAGCACT +TTGGGAGGCCAAGGCGGGCAGATCACGAGGTCAGGAGATCCAGACCATCCTGGCTAACAC +GGTGAAACCCCGTCTCTACTAAAAATACAAAAAATTAGCTGGGTGTGATGGCAGGCACCT +GCAGTCCCAGCTGCTTGGGAGGCTGAGGCGGGAGAATGGCGTGAACCCGGGAGGCGGAGC +TTGCAGTGAGCCGAGATGGCGCCACTGCACTCCAGCCTGGGCGACTGACCGAGACTCCGC +CTCAAAAAAAAAAAAAAAAAAAAGAAAAGAAAACAAAAAGATTGTACAATATGAGATATT +ATAAATGTTTACATCATTTAAGGTCTGCAAAAAGATGCTACTTACTGAAGATGCTCCTTC +ATTAGTGACTAATACATATTAGAAGTCAGCAAAAGTAATGGAAAAGCTAGGTAGAATCAA +AATTAAAGAAAGAACTGCCAATCAGTTCTCCTTTCTCTTAAAACAAAACATCACTCCCTG +CATGACTGTTAAAAACGGGCTAAGTAGCCCTTGTATTGTGGGAAGATCAGAAATCTGTTT +AACAAAAATGGCATACTTTCTTAAAAATAATGGTCCAAAACATTAGTTCAATTCAACAAT +TACTGAATACTTACAATGTACTCGATACAAACACTTCAAATCCTGCTGTTTGAGGAACTC +ATCATAAAGCAGACAGACTTTTAAAAAAATCACATACAAGTGATGAGGGCAATCAACAGC +ATTAGCATAAACAAGGTACAAAGGAGCAAATAATTATTAGAGGTGATACCTGAGATTTCT +TCTTTTGATTTGGATTTTGAAGGATGAATTAGTTTACTAGCCAGAGATAAGAAAGAACAC +TAAAGAATAAGGTGCAACGTATACTGAAAGGCAGGGAACCATACAATTCAGTTCTGGATT +TCAAGATCTTCAAGTGCTAGAAAGGGGCCATTAAAAATGACTGTGGACAGGGAGAAAGGG +CCTATTAATACAAGGCCTTGACTTTATCCCGTTGAAGGGTTTTAAGCAGGCAAGTTATAT +AATCAGATACGACTTTTAGAAACTCAACACTAGCTGCAGTGAAGGATGGTACAGATTGGA +TAAGAATGTGTAGGCAAAGATTACTGTGACAGTCCAAGTAAGAGACGAAATTATGCTATT +ATGAACTAAAGTAAAACAACTCAGTCATTATCTTCCTATTACTATGTAGTAATGCTCAGT +TAAATTCATTTTGTCATACTAATTTTAGCTCTGAAGCACAACTGCTTTAATAGAAAATGA +AGCCTTCGGCCGGGAGCGGTGGCTCACGCCTGTAAATCCCAACACTTTGGGAGGCCGAGG +CAGGTGGATCACCTGAGGTCAGGAGTTCAAGACCAGCCTGACCAACATGGTGAAACCCCA +CCTCTACAAAAACAAAAAAAACAAAAAAAACAAAACTAGCCCGGCGTGGTGGCAGGCGCC +TGTAATCCCAGCTACTTGGAGGCTGAGGCAGGATAATCGCTTGAACCTGGGAGGTGGAGG +TTCGCAGTGAGCTGAGATGGCGCCATTGCACTCCAGCCTGGGCAACAAGAGCGAAATGCT +GTCTCAAAAAAAAAGAAAAAAAAAAAGAAAAAGAAGAAAAAAAAGAAAATTAAGCCTTCA +GTACTTTGTAGCTACAGTCACAAGAAACCATGAATTGATTTGTGTTGTTCTAATAATGCA +TCATAAATCTGACCACTGGATGAGATATCAGATATTTTACTTTAAAGCCTGAATAATTTA +TGATCTTTCACTAAAATACAGCAACTACTACTAGCTGAGCTATCAGAGACTTCATGTTAA +AGCCAAATATGTATGATCTTTCTCAAAAGCAGAGCAGTAAGTATCCAAAGACCATCAAAT +TAGTTTGTCAATTCGCTAGATTTAATTTTCATTCATTAAATATCTCATTCTTTTTAAGCC +CATCACGGGGATCAAAATAGACCACCATCGGATTCTGACTTTCCTTACCTGATTCCAACG +TCTCCTCCCCTTCTGGTAGAAGCCTAGCTTTCTTAGCATTCTGTGGAGCATCATCACCAT +TGTCCTCATATATGTTAGACCATTTTATTGCCATGTCAAGCTCTGGAGGCGGAGGCTTCT +TCTCAGTGGTGTAGGTCTCAGGAGGTGGTACATAATTTGACTTCCATATTTTGAATTCCT +TTGGAGGCTGTTAAGCAAGCACATTAAGAAGCACTGTGACGAACCGAGGTTCCTACGATG +GACGTGGGCACATGCAACTCCCTGCCGTTCGCTTATCGTTCAGGCTGACTTTTTTTTTCT +TTAAGGTTGAAAGACACATTTTTCCATCAAAATCACAATACTGTTAAGTGAAAAGCCAAA +GGGTTCCCTATATGAATAAAGCTAATAACTTTTAGTTACCAAAGAAGAATCCAGTCTCAG +AGATACTACGCCAAGGCTGACCCCTTCAGGAGGCTGCAGCAGACACTGTCTTGGAGGCAG +CACCGCAGGCACTTCGGCGTCAAAGGGAAGGGGTCTCAGGGAGAAGCTGCAGCGGGGGGG +GCGGGGGAGTCACCACTGTTAGTCCTCGCCGCGCGGGGTCGGGGCACCGAGCGCGGAGGT +TTGGGTCTCCTCACAAGGGGCGGGGCTGCGGGTCCGGTCTAACACCCACCAGGCGGGGAG +AGGGGGCCAGGTTTCCCAGGGCTTGAGGTGGGAGGGGGTGGTGCGGCATCCCGCGGGGGT +GACTGCGTGTGGGGGGATGGACAGCAGGTCCCCAGCAGGGGGCTCAGGAGAAAGGGGGCG +CAGGCCGGGGCCGAGACCGAGAAACGGGGTCGGGGACCTCACCTCCTCAGGCGCCTTGAC +GACGTGCCTCTCCCAGTCTATCTGTTTGTTGAGCGGATTGTAGAGAAAGGCCGGGCGAGT +CACGCTCCTAAACAGCTCGTCAGGTCCCGGGAGCCGCTTCTCCGCCTTGTTCCTACAGCC +GCCCGCCGACTTCGCCGGATCCGGGGTTCTGCGACTCGTCTCCTCCGGCTCGATGTTATC +CTCCTCGTCCGAGGAGCCTGAGCTGCTGCTCCCGTATGCCGCAAAATAGCTCAGAGGGTC +CTTCTCCTCCGCTGCCATGACGGCTGCGAGCGACAACCCAGCACTCCGCCGGAAGCC diff --git a/test/csq/ENST00000294661/ENST00000294661.fa.fai b/test/csq/ENST00000294661/ENST00000294661.fa.fai new file mode 100644 index 0000000..c2a7be8 --- /dev/null +++ b/test/csq/ENST00000294661/ENST00000294661.fa.fai @@ -0,0 +1 @@ +1 9717 23 60 61 diff --git a/test/csq/ENST00000294661/ENST00000294661.gff b/test/csq/ENST00000294661/ENST00000294661.gff new file mode 100644 index 0000000..cbb4e04 --- /dev/null +++ b/test/csq/ENST00000294661/ENST00000294661.gff @@ -0,0 +1,6 @@ +1 ensembl_havana gene 1 9717 . - . ID=gene:ENSG00000162642;Name=C1orf52;biotype=protein_coding;description=chromosome 1 open reading frame 52 [Source:HGNC Symbol%3BAcc:24871];gene_id=ENSG00000162642;logic_name=ensembl_havana_gene;version=9 +1 ensembl_havana processed_transcript 1 9717 . - . ID=transcript:ENST00000294661;Parent=gene:ENSG00000162642;Name=C1orf52-003;biotype=processed_transcript;havana_transcript=OTTHUMT00000027614;havana_version=2;transcript_id=ENST00000294661;version=4 +1 ensembl_havana exon 1 2747 . - . Parent=transcript:ENST00000294661;Name=ENSE00001388570;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001388570;rank=4;version=2 +1 ensembl_havana exon 8569 8767 . - . Parent=transcript:ENST00000294661;Name=ENSE00003676223;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003676223;rank=3;version=1 +1 ensembl_havana exon 8980 9106 . - . Parent=transcript:ENST00000294661;Name=ENSE00001870157;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001870157;rank=2;version=1 +1 ensembl_havana exon 9403 9717 . - . Parent=transcript:ENST00000294661;Name=ENSE00001067212;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001067212;rank=1;version=4 diff --git a/test/csq/ENST00000294661/non-coding-boundary.txt b/test/csq/ENST00000294661/non-coding-boundary.txt new file mode 100644 index 0000000..d403918 --- /dev/null +++ b/test/csq/ENST00000294661/non-coding-boundary.txt @@ -0,0 +1,3 @@ +9715 GCCGGAAA G non_coding|C1orf52||processed_transcript +9715 GCCGGAAA G non_coding|C1orf52||processed_transcript + diff --git a/test/csq/ENST00000294661/non-coding-boundary.txt-l b/test/csq/ENST00000294661/non-coding-boundary.txt-l new file mode 100644 index 0000000..d403918 --- /dev/null +++ b/test/csq/ENST00000294661/non-coding-boundary.txt-l @@ -0,0 +1,3 @@ +9715 GCCGGAAA G non_coding|C1orf52||processed_transcript +9715 GCCGGAAA G non_coding|C1orf52||processed_transcript + diff --git a/test/csq/ENST00000294661/non-coding-boundary.vcf b/test/csq/ENST00000294661/non-coding-boundary.vcf new file mode 100644 index 0000000..e6d2795 --- /dev/null +++ b/test/csq/ENST00000294661/non-coding-boundary.vcf @@ -0,0 +1,6 @@ +##fileformat=VCFv4.2 +##contig= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO +1 9715 . GCCGGAAA G . . EXP=non_coding|C1orf52||processed_transcript;type=ENST00000294661:85725353-GCCGGAAA-G non-coding exon boundary overlap diff --git a/test/csq/ENST00000295641/ENST00000295641.fa b/test/csq/ENST00000295641/ENST00000295641.fa new file mode 100644 index 0000000..05227d4 --- /dev/null +++ b/test/csq/ENST00000295641/ENST00000295641.fa @@ -0,0 +1,312 @@ +>2 2:220462562-220481193 +TTTTCTTCCGGGGCGGGACTTCCTTTCCATCATTGATAGGCGCCGGGCAGCTGAGCTGGT +AGGAGGACCAGACGGGGAGGTTCGGTATGTCTGACCAGGACTTATGTTCCTCGAAAGGGC +GGCCAGGAGGATGCTCTTCCTCTCTTTTCTTTCTCGCCTTTTTCTCCGCATGACGCCTCG +GTTTGCGCGGACGCCCTGGGCTTTTGGCACTACCGCCCACCTGAGGCTCTTCCGCTTCCT +CTTTCCCCCCCCAGGCTCCGCCCCCCAGCGTCCCGTGGCCATGACGACCGCTCAGAGGGA +CTCCCTGTTGTGGAAGCTCGCGGGGTTGCTGCGGGAGTCCGGTGAGTGGACTTCCGGTTG +GGCTGGGCCTCGGACCTCGGACGAGGTGGGGGTGGTGCTTTCTGGAGACACGCCCTGAGA +GTCATGGAGTTACGACTGGTAGGGTCACCAGGTGTCAGAGTTCAATTTCTTTACTTTTCC +CAGGTTTGTTCGCCCTTACAGTGTCCTTTGCCTGTGATAGCCTAAACTCTAGCCGTCCTT +TGAGGCCAAAGGGCGGTATCCCTCCCTCCGTGCCTTCTCTGACACTGTCAGAAGGAAGTG +ATCATTACCTGACTAAAAGCCCCTCAGGACCAGGGACTGATCTCGGTCATAATCATTATT +GTGTAGCAAGGTACTAAATACAGTAGATAGAAGCACGAGATTTGGAGTCGGACCCACTTG +GGTTGGAATATCAACCCTCTTTCAAACTTGCCATACTGTTTCCTGAGGCTCAGTTTTCCT +CACAGATTGGCATAGTGATTGTACTTAACATTTGTGGGGATTCGTTTTAATTCATGTATT +TAGTACAATGCCTGCAAGTATAGTAACTGCTTACAGTTGGGAGCTATTGTTATTGTAATG +ATTTCCCTGATGCTTGGCACTGTGCCTGGGCATAATGGAGCCACAGTAGTTGTTGAATAC +TTGGTTGGCATTAGTTGTGGTAGAAAAAGCCTTGGCTTTGAGATCAGATAGGAGAAGTAA +CTTCCTACCAATTATATGATCTCCATCAAGATTTTTCACTTTTTTGAACCTCAATTTTCA +TATCTGTAAGATGGGGTTAATAGTGCTTCTCTTTGAGAGATTCTGAGAAGGTTTGAATGA +GATACCAAAGTCATCTGGTACATACTACAGTTAATGTTAGCTGTCCTCCATCACTCCATG +CTCCTATTGACGATATCTGTGGAAGCTCTCTTTATAGCAGTTTTCTTTTCTTTCTTTTCT +TTTTTTTGAGACAGAGTCTTGCTGTGTCACCCAGGCTGGAGTGCAGTGGCGCAATCTCAG +CTCACTGCAACCTCCACCTCCTGGGACGAAGTGATTCTCCTGCCTCAGCCTCCTGAGTAG +CTGGGACTACAGGTGTGCACCACCATGACCGGCTAATTTTTGTATTTTTAGTAGAGACGG +GGTTTCACCATGTTGGCCAGGTTGGTCTTGAACTCCTGACCTCAAGTGATTAACCTGCCT +TGGCCTCCCAAAGTGCTAGGATTAAAGTCGTGAGCCACAGCACCTGGCCAGTAGCAGTTT +CATTTCCTGGCTTGTATTGATAACTTTGCAAATGTCTTATATCCTTCTCTGGGAGGAGAC +AACTAGGAGGCCCTTTGAACGTGGGAAGAGTCCTTGAACCATGTCTGTATCTATCCTCAG +TGTCTAGTACATACAGAATCCTTCATGTCAGGTTGTAGGACTTGTTAATTTATTCAGTGA +TGAATGGTGGGTGTGTGAATGTGTGACTACAAGGAGGTAGCAGGAGAAGAGCTTTGTGGC +AGCAGAATAGTTTTGTATCTTGATTGCGTGGCTGCAGGAATTTATATAAACAGCATATAG +CTATATATACATATTGTACCAACATCAGTGTCCTGAATTTTTTTTTTTTTTTGAGATGGA +GTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGTATGATCTCGGCTCACTGCAACCCCT +GCCTCCCTCCCAGGTTGAAGTGATTCTTCTGCCTCAGCCTCCCGAGTAGCTGGGACTACA +GGCATGCACCACCATGCCCTACTAATTTTTGTATTTTTAGTAGAGACGGGGTTTCACCAT +ATTGGCCAGGCTGGTCTTTAACTCCGGACCTCGTGATCCACCCGCCTTGGCCTCCCAAAG +TGCTGGGATTACAGGCGTGAGCCACCACGCCTGCCCTTTGTGTTTTTTTTTTTGTTTTTG +TTTTTTTTTTTTTTTTTTTTTGAGATGGAGTCTACCTCTGTCACCCAGGCTGGAGTGCAA +TGGCTCAATTTCGGCTCACTGCAACCTCTGCCTCCTGGCTTCCAGCTGTTCTCTGGCCTC +AGCCCCTCGAGTAGCTGGGATTACAGGCGCATGTCGCAATGCCCAGCTGAGAATATTTGT +ATTTTTAGTAGAGACGAGGTTAGAGTCGTAGAATAATTTTTTGTGTTTTTAGTGGAGACG +GGGTTTCACCATGTTGGCCAGGTTGGTCCTGAACTCCTGACCTCAAGTGCCTTGCTCCCA +AAGTGCTGGGATTACAGGCCTGAGCCACGGCAACCAGCTCAGTGTCCTGACTTTGATATT +GTACTATAGCTATATAAAATGTAACCATTAGGGAAAACTGGGTAAAGGATACAGGGGACC +TTTCTGTATTATTTCTGCAGCATTCTTTGACTCCATACTTATTATATTTTTTAAGCCAAA +AAAGCATTCCTTCATGCCTAGCTTGTAGCTGCACTTTTTTAGGTGCAGTGATGAATACCA +GAGTGATCAAAAGATGCCCTCAAGGATGAAAGTCTCATTAGAGAGAGCAGTTTTAACAGA +CAGCAATAACAATGCCTTAGTGCTATAATGAATAGTTATTCTATGACATACTTTTTAGTA +TTGTTTGAAAGTTTCTACAGATGTGCTTTGCAATCAGAAAAAGAAAGAAAGATAAAACTT +CCAATTAACTTTTGTGTAATAATGAGTGACTGCAATATGAAAATTCAGCAGTATTACTTC +TTGAGGCGGCTTCCTGGAGGAGGCTGGTCTCAAGCTGGGCGGTGGAAGGGGGTGTCTCAT +AACAAGAGAGAACTGTGAACCAAGCTGGCTGTATTTCCAGCACTGTCAGTAGATGAGGCT +CTTTTGAGCAGAAGGTGAAAGAAAATTTGGAAGAGTTGGTTGGAGTTGTGTAGCCAAGCA +GTCTCATCAGGCTGAATGAAATGTTAGGACTTTTTTTGAAGATGAGGGGAGCCATTGAAT +GCTTTTGAGCTGAGAAGGAGATAGAAAATTTGATCCTGCAATAGAAGATCTACAATATGG +ATTGGAGTGGGTATATTTTGGCATCATAGAGCCTTAGAATAAAGAGAAAAATCTTTTCAC +TGTGTCTTCCCTCCTGTTTGCCCCTTTTTCTGCAGGGGATGTGGTCCTGTCTGGCTGTAG +CACCCTGAGCCTGCTGACTCCCACACTGCAACAGCTGAACCACGTATTTGAGCTGCACCT +GGGGCCATGGGGCCCTGGCCAGACAGGCTTTGTGGCTCTGCCCTCCCATCCTGCCGACTC +CCCTGTTATTCTTCAGCTTCAGTTTCTCTTCGATGTGCTGCAGAAAACACTTTCACTCAA +GGTTCTGGGTGTGGGGAAGAGGCAGGATGTGCAAGGAGCCCAAGAGAATGATGGAAGTTG +GGGATAGGGTAGGGGTGCAGAAGTCTGCAGTGCCAGGATCCAGAGGGTGTCAGAGGTACC +AGTGGTTGTGCTAAGGAAGGAATGTTGAGGGCAGGAAGATCTGCTGTGCCTCAGTAAATT +GAGTTTTTTTTTTTTTTTCAGCTGGTCCATGTTGCTGGTCCTGGCCCCACAGGGCCCATC +AAGATTTTCCCCTTCAAATCCCTTCGGCACCTGGAGGTATGGGGACACGGGGGGATGTTG +GTGCACAGCACCCAACTTGAGGCAGCCCCTTGGGGATGGGAAAGAGAAGAGCCTCTTTGG +TGAGGAGGCCAGGCCTGAGTATACCCATTGCTCTGCAGTCATGTGATATCCACTGTCTTT +CCATTTACTGCTTCCCTAAATCATAGCTGGGCTTTGTGGTCTTCTCCCTCCTCCCAACTA +GGGGATGGGGATGAGGTCTTTGTCTTCTGTGGGGTTCTGCCTTCCTCCCTCCTCTTTCCT +TGTCCCAGCTCCGAGGTGTTCCCCTCCACTGTCTGCATGGCCTCCGAGGCATCTACTCCC +AGCTGGAGACCCTGATTTGCAGCAGGAGCCTCCAGGCATTAGAGGTAAGGAGAGTGAGGG +GTGAGCTCAGACACCTCAACTTGAGAGATGTAGAAGACCAAGCTCTGATGTTCTCCCCTC +TCTGCAGCTCTCCCTGCCTCCTGCTTCCCTCTAGACAGTGTCCTCACTCCCTCTCTGTGT +TCCCGCAGCACTCTGTAACTGCCTGTATATTTATAGTCGTACCTACCATATTATATTACA +TATTCTAGTGTCTACCTTCCCACTGTCCCTACAGTGAGTTCTTGGGTCAGGGACCTGGGC +TTTAAGCCTGTATCTTCAGATGGAGTTCAGTGTATAAAAAATGAATGAGTGACTGGGTGG +TAGAGCTTGGCCTTGGCATAGGGAGGAAGGGGAGGGTGGGGTAATGAAGCACCCATCTGT +CTGCTCAGGAGCTCCTCTCAGCCTGCGGCGGCGACTTCTGCTCTGCCCTCCCTTGGCTGG +CTCTGCTTTCTGCCAACTTCAGCTACAATGCACTGACCGCCTTAGACAGCTCCCTGGTGA +GTGCCTCAGAGGGAAGAGGGTTTCGAGGAAGGGCAAGGCCAGGCCTTTGGGGAGGAGGGC +CAGCTGGTTGACCAGATAGTATTGTAGTGAACATCGATTCTCTGCCTCCTCCCCGTCTCT +CTCAGCGCCTCTTGTCAGCTCTGCGTTTCTTGAACCTAAGCCACAATCAAGTCCAGGACT +GTCAGGGATTCCTGATGGTGAGTATGGGCAGTTTGGCAGCTGGCACACCATGGGTCTTTG +ATTGCTCTGCTCTCACTCTCTCTCCTTGACCAGCTTTTACTCCCACCTTGCTCTTGCCAT +GAGGGTGGAGCTGCATTCTGGGAGATAGCACTGCTTAGACACTAGCATCAGACAAACCAG +AGTTCATATCTCAACTTCTAATACCTGTGCAACTTTGAGCAAGTTAGTTACCTCTTGGTT +TCTTTACCTGTAAAGTAGAAATCACAAGAGTACCTGGTTTTTTTTTTTTTTTTTTTTTTT +GAGATGGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGCGCAATCTCAGCTCACTG +CAACCTCTGCCTCCCAGGTTCAAGCAATTCTCCTGCTTCAGCCTCCCAAGTAGCTGGGAT +TACAGGCACGTGTCAACACACCTGGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCA +CCATGTTGGTCAGGCTGGTCTTGAACTGCTGACCTCAAGCAATTCACCTGCCTTGGCCTC +CCAAAATGCTGGGATTACAGGCATGAGCCACCACGCCCGGCTGAATACCTGCTTTTATAG +TATTAAAATGATTGTGAAGAAGTACCCAATGTTGCTTAGTCTAGTGCCTAGCTCAGAAAC +TGGTAGCTTTTGTGATTATGATGAAGAACCTTTCTTCTGGGTCCTCCCATCCACCTGTCA +GAGATAAAGCCGAACTAGTTAAAGTGGTAAGGACAGATTTTTTTTTTCTTTTTTTTTTTG +AGGCAGAGTCTTGCTCTGTCACCCAGGCTAGAGTGCAGTGGTGTGATCTTGGCTCACTGC +AAACTCAACCTCCTGGGTTCAAGCAGTTCTCCTGCCTCAGTCTCCCGAGTAGCTGGGATT +ACAGGTGCCCGCCACCATGCCCAGCTAATTTTTGTATTTTTTAGTAGAGATGGGGTTTCA +CCATCTTAGCCAGGCTGGTCTTGAACTCCTGACCTCATGATCCGCCCACCTCAGCCTCCC +AAAATGCTGGGATTACAGGTGTGAGCCACCGTGCCCGACCAAGTAAGGACAGATTTTTTA +TCAGTGATAAACTATTGCAGCGGGGAAGAGGGTGCAACCTGAACTGAACGCCACTTCAAT +TTGTGCAGAGGTGGCTGGGCATTTTAAAAGGAGAGTGAGGGAATAGGAAGGGGAACTGTG +AGGGCTTGAGCAGAGTAAGGGAAGTGGAAATGTACGAAAAGCAGAAGTGGAGGTTGATTC +ACATGAAGCCCTTCTGGGTTTGCTAAAAGTTAGGCTCCTACCTTCCCACAGAGACTGGGA +GATGGGAGCCCTGTCATCAGGTGTTGGCTAGAACAAATGGGAAATTCTTTTGGCAGCCTT +GACTTTTCCCAGGCAGGAGCTTAAGGGGGCTAGAGTCACCATTCTAGGGATGCATCCTTG +AGATATTAGAACTTTGCTGTTTTTGTTCAGGTTTTTTACTGTGGGGGTTGGAGGAGTCAA +CAAAAATAATTTGTGTTGAATTTTGTTGAACTTGTGCTGAACAAGTCTGCAGTTCTTAAC +AGGCCAAAGTTGAGGCCTAGTCAAAAAGAAGGCCCAGAGGAGCCTGAGTAGGGTTTGATC +AAGGTGAGAACCTCCTCTAATTCAGGGAAAGAAGAGACACTCCTCTTTCCCCTGAACAAT +ATAAATCCTTTTCTTCCTTGATCACCTTTTGTTCACTAAAAACCAACTGAGCCATTTATT +GGGACTTGGTAGTGGATGAATTTTGCTGGATGGTGAGAGTGACCAGGCATTTAATGGGGG +ACATTTCTATGGAAACAAAAAGGGAAACAAAGATGAATGGTTGGAGCAGACTATAAATCC +ATTTTCTGAGTCCAGAGGGCAGCCAGTTGAGATTTCTAGGTGTTGAGCTCTATGTTTCTT +TAGATGGTGGAATGAGGATAGCAGTGGCAACCGATGGATTTCTTCGTTTGTAGTTTGAAT +GTTTGTGGTGATAGCATAGACAGTGTTGCAGTCACGGTTATTTCCCTGAACAGAGCCTGG +AAGATACAGAAGTGTCAGTGGACTTTTTTCCTTTTTTTTTTTTTAATGAGACAGAGTTTC +GCTCTTGTTGCCCAGGCTGGAGTGCAATGGCACGATCTTGGCTCACCGTAACCTCTGCCT +CCCGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACAAGTGTGTG +CCACCACGCCCAGCTAATTTTTGTATTTTTAGTAGAGACGGGGTTTCACAATGTTGGCCA +GGTGAGTCTCGAACTCCTGGCCTCAAGTGATCCCCCCTCTTTGGCCTCCCAGAGTGCTGG +GATTACAGGCATGAGCCACTGCACCTGGCCGGCTGGGCATTTTAAAAGAGGGCGGCGGGG +AGTGGGCAGGGGAATGGTAGGGCCTTGAGCAGAGCTGGGGGAGTGGAAATCAGGTTGGTC +CACATGAAACCCATCTGAGTTTGCTAACTAACTGGCACTTACCAAAATAAGGCCCTTACC +CTTTCACAGAGACTGGGAGACGGGGCCCTATCTTCAGGAGTTGGCTGAAACAAATGGGAA +ATTCTTTTGGCAGCTTTGACTTTTCCCAGGCAGGAATTTAAGGGGCTTGGAGTTGCCATG +CTCAGGGTGTGGCCTTGAACTGTTAGGAACAGTGCTGGTGTTGTTCAAGTCTTTTAACGT +GGGAGTAGGGGTGGATGAAATCATTTGTGCTGAGTGTGTGCAGTTTTATATAGGCCAAGG +TTGAGGCCTAGTCCAGAAGAGGTCTCAGAGGACCCTGGCTAGAGTTTGGTCAACGAGATA +ATCTTTTTCTCCCCTGTACCCCTGCCAGGATTTGTGTGAGCTCCACCATCTGGACATCTC +CTATAATCGCCTGCATTTGGTGCCAAGAATGGGACCCTCAGGGGCTGCTCTGGGGGTCCT +GATACTGCGAGGCAATGAGCTTCGGAGCCTGCATGGTGAGTGGGGGTGTGTGATGGGGCA +AGCATGGAGGGGAAGGGGGAGAGTGAGGCTGGGGCTGGCCTGGGGACCATGTGCCTCTAG +AGCCTTGAGAGGGCTTATGGGGAGTGCAGGGGTGCTCTGGCCGGTCTTTCTGCTGCAACC +TCCCCCAGTGCATGCACCACACTCACTTGCGTGTACTCATCCACATGCTCTTCCTTCCTT +CTTGCGTCCACCCCAGGCCTAGAGCAGCTGAGGAATCTGCGGCACCTGGATTTGGCATAC +AACCTGCTGGAAGGACACCGGGAGCTGTCACCACTGTGGCTGCTGGCTGAGCTCCGCAAG +GTGAGATGGGAATGCATCAGGGGCCTGGGAACCACCCTTGCACGTACCCCCCCATGCTGG +TTTGGTCAGTGCCTTCTTCACACAGGGAGGGCCAGGGCCCCAGGCCCTCCTCATTCTCCC +CTTCCTGCCCCTCAGCTCTACCTGGAGGGGAACCCTCTTTGGTTCCACCCTGAGCACCGA +GCAGCCACTGCCCAGTACTTGTCACCCCGGGCCAGGGATGCTGCTACTGGCGTGAGTGAT +CGTCCTGTGTCCACTCTTCTTCCCCTTTCCTGCCCAGTCCTCCCCCACCTTGCACCCTCT +TGCCATCCCTGGGTGAGGGGCCAAGGACCTGGACCCTGCTTACTGTGTTCTTAATACCTG +GAGCTCAGCAGGATGGGCCTACCACATACTCCCTCCCCCTTTTTGTCTTTGCTCAGTTCC +TTCTCGATGGCAAGGTCTTGTCACTGACAGATTTTCAGGTCGGTGTGGTTGGGGGGCGAG +GACTGTTGGGGGAAGACACGAAGGGAGGGCGCTGGGGAGAGAACAGAGGGCTGGCTGGTG +ACAGGGTCTTCCTGGTCAGTGGAAAGTAGGGTCCCGCCTTTTGGCTGGCTTGGGCAAGGC +AGAGGTGCTCCCAGGCTCCAACCTCTCTCTCCTTCCTGTCGTCACGTGCCAGACTCACAC +ATCCTTGGGGCTCAGCCCCATGGGCCCACCTTTGCCCTGGCCAGTGGGGAGTACTCCTGA +AACCTCAGGTGGCCCTGACCTGAGTGACAGCCTCTCCTCAGGGGGTGTTGTGACCCAGCC +CCTGCTTCATAAGGTTAAGGTAAGCAGCGTCCTCCGCTGCCTTGTGCCTGCGGTTGGGTG +TCTCTCCGGGGACTCTGGGCTACAGTGGGCAGGGAATGGTAGGAACTGTGCTTGCACGTG +GTCAAGGTTTCTTTGATAGGTTGGATGGCCAGCCGTGGATGGCAGGGCTGGAGGCTTGGC +TTTCACAGAACTTCTTCCCTCCACCAACCTCAGAGCCGAGTCCGTGTGAGGCGGGCAAGC +ATCTCTGAACCCAGTGATACGGACCCGGAGCCCCGAACTCTGAACCCCTCTCCGGCTGGT +AAGTCAGCTTCATCCCACTAACCTCTCTCGTCCCCAGCGAGCTCACTCTAATTTTTAAGT +TACAGTGAAGATCTGCTGGAAGAAATGTTATTTTTTGTTGGGGTAGAGTATTATAGAGGG +CTTCTTAGTCTTTTTTCTTTTCTTTTAGTTTAGGGAAAGGAGAAGACTGCTTCTGGGAGC +ATTTTGAAAACTTTTCGAGGAACATTAATTTTGTGGGGTGTCAAGAGATCATGTAGGCCA +GGTGCAGTGGCTTACATCTGTAATCCCAGCACTTTGGGAGGCTGAGGTGGGAGGATTGCC +TGAGCCCAGGAGTTTGAGACCAGCCTGGGCAACATAGAGAGATGTCCATTTCTACAAAAA +AATTTTTAAATTAGCCTGACGTGGTGGTGTGCGCCTGTAGTCCTAGCTACTTGGGAGGCT +GAGGCAGGAGGATCGCCAGAGCCTGATAGTTCAAGGTTGCAGTGAGCTATGATCATGCCA +CTGCACTCTAACCTGGTGACAGAGTAAGACCTTATCTCTTAAAAAAAAAAGTAAAAAACC +CCAAAACAAAAGAAAGTGTATATGTATATATATAAAATAATAGGATTGTGGCCAGAGAAG +TTTGAGAAATGTGAGGTTGAAGAGAAATAGGTGTGTCAGCTGCCGGCCGTCTCGGGCCCT +TCAGGATGCTATCATGTATGCTGAGTCTCTGGAAGTAGCATAGGATGCGCAGCTTGGATT +GCATGTGACCACAGGGTTCCATAGGACACGCTTTAGTACATGCCGCGGAGGGGACGCCTG +TAGCCTCCCTTGCCCGTGTCCCCATACACAGCCCATCGCCCCCTCATCGCTGAGGAGCAC +CGTTGAAGGATTTGGGGCCATCTGTGTGGGGCAGGCTTGCTCAGTTCTGGGTTCCCCTCC +TGCCTAGGATGGTTCGTGCAGCAGCACCCGGAGCTGGAGCTCATGAGCAGCTTCCGGGAA +CGGTTCGGCCGCAACTGGCTGCAGTACAGGAGTCACCTGGAGCCCTCCGGAAACCCTCTG +CCGGCCACCCCCACTACTTCTGCACCCAGTGCACCTCCAGCCAGCTCCCAGGGCCCCGAC +ACTGCACCCAGACCTTCACCCCCGCAGGAGGAAGCCAGAGGCCCCCAGGAGTCACCACAG +AAAATGTCAGAGGAGGTCAGGGCGGAGCCACAGGAGGAGGAAGAGGAGAAGGAGGGGAAG +GAGGAGAAGGAGGAGGGGGAGATGGTGGAACAGGGAGAAGAGGAGGCAGGAGAGGAGGAA +GAAGAGGAGCAGGACCAGAAGGAAGTGGAAGGTGAGCCCTTTGTGGGCTGGGGCGAGCTG +AGGCCAGGGGCCCTTGGGATGTTTGTGAGTGGTGGGGCCTGGCGGGTGGAGGGCCAGTTC +GGGGGAGGGCAGAGTGTGGGTACTTTCCCTCCCTGCAGGCCTTTTCTCTTGGTCTCTCCA +CAGCGGAACTCTGTCGCCCCTTGTTGGTGTGTCCCCTGGAGGGGCCTGAGGGCGTACGGG +GCAGGGAATGCTTTCTCAGGGTCACTTCTGCCCACCTGTTTGAGGTGGAACTCCAAGCAG +CTCGCACCTTGGAGCGACTGGAGCTCCAGAGTCTGGAGGCAGCTGAGATAGAGCCGGAGG +CCCAGGCCCAGAGGTCGCCCAGGCCCACGGTGAGTGGGGCGTGGCAGGGTCTCTGGAGGA +GCCAGTTATGGGAACATGGCTGTTGTGTGCCCTGCACTGGGCTGGGCATTTCTTTCAGTC +TCTCCTTGGCACTAGGAGCCGAGGAGGGGAGCCTCAGAGGTTGCAAGCACTCGGGAAGCT +GGGCTGAGGAGCAGGGATTCTGTGCTGGAGCTTGGACGTCAGTACAGGCCTTTGACAGGC +TTCAGAGGTCCTGCCATCCTCCATGCTCTCAGCATCCCCTCATCCCTCTGATCACCGCCC +CTGCTGTTTTTCACCCGGTCCCCCTCTTGCTGCGCAGGGCTCAGATCTGCTCCCTGGAGC +CCCCATCCTCAGTCTGCGCTTCTCCTACATCTGCCCTGACCGGCAGTTGCGTCGCTATTT +GGTGCTGGAGCCTGATGCCCACGCAGCTGTCCAGGTGATGGCGCCCAGAGTGGGGGCCCA +GGAGGCTGTGGGGATTAAGAGAGCCAGAGGGAAGTGGCAGCAGGCCTGAGGGCCGGGGGC +CTGTGGGAGGTGTCCGTCTGGGGTCCGCCTGCTCACAGCTGCCTCTGATCCACCCTCTGT +CAGGAGCTGCTTGCCGTGTTGACCCCAGTCACCAATGTGGCTCGGGAACAGCTTGGGGAG +GCCAGGGACCTCCTGCTGGGTAGATTCCAGTGTCTACGCTGTGGCCATGAGTTCAAGCCA +GAGGAGCCCAGGATGGGATTAGACAGTGAGGAAGGCTGGAGGCCTCTGTTCCAAAAGACA +GGTACAAGTCCTGCCCTTGACCTCTCTGCCCACACGCCTCCCCTGTTCCAGGGAAAGTGG +CTCTGTGTAGGGGAGTGTGAAGGGGGAGCCCTAGGGAGAAGGGGCTAGAGTGGAGAGCAG +TTGTTCTGCCTGGAGGAAAAAGAAAACCGTCTGCCTGCTGCATTTACAAAAAGGAAAACA +GAAAAAAAGAAGAAACTATATCCTGTTTTTTTTTTTTTTTTAACTCTAAAAGTCAGGAAA +TGCAATCTCTGTAACTGTGCTTAAACATACTCATTATTTTTTCATAACTTGAAGGCTTGT +TGTGTTGGGGATTTTTTGGCTGATATTTCAGACACTACATAAAACCTAATGAGCCCTCAC +TGCAGTATTGGATTGTGGTGCTGCCTCTGCCAGCAAGTGTAGCTGTTGAGTGAGATGCTT +GGGGAGTTGGCTTGGTTTATCCTTCCCGGCTGACCTTGGAAGGTACATAATGTCCTGTGG +CATTTCTTCATGCGCTAGTCCTTAAAACAAGAATTGTTTCCATTGTAGACCAGTCAGCAC +TATCTTTGAAGAAGACATTGAAGAAGAAATAAATATTCTTGATAACAGCTCTGTGGAAAT +GCCAGAATTTTATTAGACGGTTTTCTCTTCTTGGCGGCAGCTGGAGCAGGGGTTTAGATT +TTATTCAGAAAATGGAGCCCTGCTCCATTCCCCACTGTGAACTGGCCTGGGCATGCAGCC +TTAGTGACACAGCGCAAACAGAAACAGCCCCCAGCCCCTCCCGGACCCTGGCTGTACACC +ATGAGGTGCTGTGGTCTCTGGAGCCTCTTCCATGGTGGCGTTATTAATGAACATTACTGT +GGGCTCTGTTCTCCTTTAATTTTTTTTTTTCTTTTTTTTTTGAGACGGAGTCTCGCTCTG +TTGCCCAGGCTGGAGTGCAGTGGCACAACCTTGGCTCACTGCAAGCTCTGCCTTCCGGGT +TCACGCCATTCTCCTGCCTCAGCCTCGCAAGTAGCTGGGACTACAGGCGCCCACCACCAC +ACCCAGCTAATTTTTTGTATTTTTAGTAGAGATGGGGTTTCACCGTGTTAGCCAGGATGG +TCTGTCTCCTGACCTCGGATCTGCCCACCTTGGCCTCCCAAAGTGCTGGGATTACAGGCG +TGAGCCACCACGCCCGGCCAACCATTCTCCTTTCACTTGCACCTCAGTTACCTCCTCTGA +ACAAAGAAGGGAATGAACTCACCCCATGGTGCTGTTACGCTATTTAAATGTGACAGTAAG +GCACCAAGCAGAGGGCCTGGCACAACACAAAGGTCTCCTGTAAATGGTAGCTGCTGCCGT +TGTCCCCAGCTGTATGGTCCTGGGCAGCATGTGTAAATGATTTAATATTTTCTTTCTTCT +TTGCAAAATGGGATAGGGAGAGTTTCTCTGGTGATGAAATGCGATCATAGTGGCATAGGA +GGTAGCGCATGCCCATCACGGTGTAGCTGCTCAGAGTGCTGCCTCTCTCATTGCTGATCC +ATGTCCTGATTCCTTCCCAGCTTCCTGACACTAAGGATGAGTATAAGATAGATGCTATTG +TCATCCCTGTTTTATAGACGAGGAACCAGGCTCACAGAGCTTAGATGACTTGCCCATGAT +TACAGAGCCATTAATTGATGGAGCCTGGAATTGGACCGAAATTTGGCAACAGAGTTCTCT +GCCTTTCCAGACCTGTTGATTTTGGTCTTTCAGACGTTGCTAGGAGAGCCCTGAAGTACT +TGATCAGCCCAAGTCTGTAAGAGGGCATAAGAGCAGGTCCTGGTTGTGTTTGGCCCAGTC +TGAGAGGGCCTAGAGTTAGAAGGTAGAGTGCACTTTGAGGAGTTTGTGGGCCAGGGTTAG +CTCATCCCTCCCTGGGGTGGGGAGTGATCAGTTGGCAGCTGTGCCGGGAGAGGGAGCTGG +TGGCCTGGGGCGCGGTGGTTGTGTATGAAGCTGGAGGCTTGGGCTCAGGGGAGACCTGAG +CATGGGGAAGGAGCATCGTGAGCATGGTGGGAGTTGTGGCACTGTGGGGGGGGCTCATGG +GGACCGTGTCCATCCTCCCTCCAGAATCTCCTGCTGTGTGTCCTAACTGTGGTAGTGACC +ACGTGGTTCTCCTCGCTGTGTCTCGGGGAACCCCCAACAGGGAGCGGAAACAGGGAGAGC +AGTCTCTGGCTCCTTCTCCGTCTGCCAGCCCTGTCTGCCACCCTCCTGGCCATGGTGACC +ACCTTGACAGGGCCAAGAACAGCCCACCTCAGGCACCGAGCACCCGTGACCATGGTAGTT +GGAGCCTCAGTCCCCGTGAGTATAGGCAAAACAAGACATAGATGAGTTTGGGGAAGGGAA +GGGGCACTGATGGGGAGGTGGAGATGGAGCCCAGGGGCTGCCATGGGCAGGCTGATGCCC +CCTCATTGCCCTCAGCCCCTGAGCGCTGTGGCCTCCGCTCTGTGGACCACCGACTCCGGC +TCTTCCTGGATGTTGAGGTGTTCAGCGATGCCCAGGAGGAGTTCCAGTGCTGCCTCAAGG +TCTGTGCTCCCTGACACTGCCCATGCCCCCAGCTGTCCAGGGTGCCCACTCGTTTCCATC +ACAGCCAACTGAGTCAGATCAAGCACTCTAGAGACCTGATCTGGCTTCTGGTTTCAACCC +CAGCAGCTTCTTGCTGTGTGGCCGTGGACACATTCCCTGGTATTTGAGTCCCAGTTGTTG +CCTGTCTGCAATGGAGATAACGATGCCTCCCTTACACAGTGGCGTGCGTCAGGGCTCATG +TTGAAGCTGCCCAGCCCAGCACCTGGCACTCATCAATGGGGCCTCCTAGCATTATTATAA +ACACATGATGTCGTTAGGCCTTTGTTGAGCACCTGTTGTGCTAGACATTGAGGATCTACA +GATCAATCTTGCCCTTGATCTTACAGTCTGGTGTGAGAAGCTGACAATGATTATGCAATA +TGCAAATGCTGTAATCGGGCTAAGGCCCTTGAAGGGGTGTCTAGTCCAGCTTGAGTGGGT +CAAGGAACCTTCCTGGGAGGTGATGTCTAAGCTCAGTCTTGAAGGGTAAGTTAAGGAGTA +GGGAGGAAAAGAATGTCTTAGGTAAAGGAAGCCGCAAATGCATGGAGGCCCGAGAGTGTC +GCTGGTGGGGAGAACTGCCCAGGATGAGGGCACCTGGACATGCAGGGCGAGGGGCAGGGG +TCCTGAGAGGACTCTGGGGGGCCGGCAGGGGCCAGGTCAGGAGCTGCCTCCTGTGTCTGC +CAAGGAGTTTGGACTTGTTTCTGAGGGCCACTGGGAGCCACTGAAGGATTTGAAATGGGG +CAGTGATGGTCAGTTTTGTGCCTTAGAATAGTTAGTCTGGCGGAGCGTGGAGGGGGTGAG +GCGACAGGCAGGGAAGCCAGCTGCTGAGGCTCTGAGCGGGCAGGGGCTGCAAGGCAGAGA +GCGGTGGTGGATGAAGAGGCTGTCGAGTGTGAGGGAAGCTCCATAGACTGGTGGGTGGGC +AGTGGGAGGGTCAGGCCGAGGGTGCTGTCACCAGGAACTCGGCTTTCAGTCTGGCCCCAC +CTCCCCAGGCCTCTCATCAGGTTTCTCACCAACTTCCTCTTCCCCCAGGTGCCAGTGGCA +TTGGCAGGCCACACTGGGGAGTTCATGTGCCTTGTGGTTGTGTCTGACCGCAGGCTGTAC +CTGTTGAAGGTGACTGGGGAGATGCGGTGAGTGAGAGGGGAGATGCAGTGAGTAAGGGGG +GAGATGGGGTGAGTTGGGGGGAGATGGGGGAGTGAGGGGGAAGATGGGGTGAGGGGGGAG +ATGGGGTGAGTGAGGGGGGAGATGGGGTGTTAAGGGGGGAGATGGGGTGAGTGAGGGGGG +AGATGGGGTGAGAGAAGGGGGAGATTGGGTGAGTGAGGGGGAGGTGGGGTGAGTGAGGGG +GGAGGTGGGGTGAGTGGGGGGGAGGTGGGGTGAGTGGGGGGGACGTGGGGTGAGTGAAGG +GGGAGATGGGGTGAGTGGGGGGCGGAGATGGGGTGAGTGGGGGGCGGAGATGGGGTGAGT +GAGGGGGGAGATGGGGTGAGTGAGGGGGAGATGGGGTGAGTGAGGGAGGAGATGGAATGA +GGGGGAAGATGGGGTGTGGTGAGCGCACGGGGGTGATGCAGTGAGTGAGGCAGGTGCAGC +TGGGGCAGGGCCTCTCTGGGACTCTCACTCCACTCTCATGCTTCTCCATTGCTCTGTCCC +CTCTCTCCACAGTGAGCCTCCAGCTAGCTGGCTGCAGCTGACCCTGGCTGTTCCCCTGCA +GGATCTGAGTGGCATAGAGCTGGGCCTGGCAGGCCAGAGCCTGCGGCTAGAGTGGGCAGC +TGGGGCGGGCCGCTGTGTGCTGCTGCCCCGAGATGCCAGGCATTGCCGGGCCTTCCTAGA +GGAGCTCCTTGGTGAGAGAGGGGAGGGGAAGGCAGGAGGGTGGGCAGGAGGGTGGGCAGG +GCCTTGGGGCCAGGCTCCCCACCTGGTACCCAGTAGCGGAGACAGAGAGGTAACAGGACT +TGTCCCTTGTAGAAGTTTCTGAAATCCAGAAATGTGGAGAATAGGAAGGGATTGAGAGGT +GGTGAGTTTAGGCTGGAGGAGAGCAGAGCCTTCTAAAGTTCCCTGGCCTGCCTCTGTCTA +GATGTCTTGCAGTCTCTGCCCCCTGCCTGGAGGAACTGTGTCAGTGCCACAGAGGAGGAG +GTCACCCCCCAGCACCGGCTCTGGTGAGTCGATAGGAGGCAGAGGCTGGGGTTGCTGCCC +AATCCTCTTTCCACAGAGCCCCAGACATGGCCCTGTGCTGAGTAGGTCCTGGGCAGCCAC +CTGTCCTCATGCCATGCCCCTTATGGGCCCCTAGTGTCTCCTCCCAACCCCCTGCAGGGC +TTTCTTCCCACTCCCCTCTCTTCAAGTCCTTCCCACCCGCTAGCTGATCTTCCTGTGCCT +GCCATATTCCCTCTAGGCCATTGCTGGAAAAAGACTCATCCTTGGAGGCTCGCCAGTTCT +TCTACCTTCGGGCGTTCCTGGTTGAAGGTGAAGCCTCTGTGCAGCTGATGCTTCCCTGGT +CTCTGTACCCTACCTTGTCACAGGCACTGGCCCACGCGCAGCACCTGTACAGTGCCCTTG +CAGCAACTGTCAGTTCCTGGAACCTGGAGAACCTCTCACTTGAGGGCATAGCTGAGTAAC +AGCCTCAGTGTGCCCTGACCCTCTGGGTGGGGTTAGGAGGCACCCAGGATCCTCAGTTAC +CCAGAGCCTTTGCTCTCGGGCCCAGGCTTTCTATGAAGTGGAGCAGCGTGGCTGAGTCGG +CCCTGCCTCATCAGTCACAGAAGGAGAGGGTGGAGCCTTGTTTCTGAGTAGGGTGGGTGT +GGGGCAGTGGGGGGCGGTAGGCCTCAGAGGTATTCCAGAGTAGAGATTCATGGAGCTTGG +GAAAGGGAGGGTCTTGGCCCCAGGGGCACAGGCTGCTTTGTGACCCACCTCAGAGTGTGG +TTCACACCTCTTCTCCCCAGCAGCACTGGGACGCTGGCCCCAGGGATCTGGGCCCCTCCA +TGACCTTCCACACTGGATGCCTCTTTCCCTGCAGGCCCTTCCACCTGCCTCGTATCCCTG +TTGCTGACTCCGTCCACCCTGTTCCTGTTAGATGAGGATGCTGCAGGGTCCCCGGCAGAG +CCCTCTCCTCCAGCAGCATCTGGCGAAGCCTCTGAGAAGGTGCCTCCCTCGGGGCCGGGC +CCTGCTGTGCGTGTCAGGGAGCAGCAGCCACTCAGCAGCCTGAGCTCCGTGCTGCTCTAC +CGCTCAGCCCCTGAGGACTTGCGGCTGCTCTTCTACGATGAGGTGTGTATGTGTATCTCC +AGTGAGAGGGAGGGAGGGGAGATGGTGAGCACAGGTTGGGGCCATGAGGGCAGGGTGGGA +AATGGGTCTAGGAACCCTGGGCATTGGTGGCAGGATGGCACTTACAGATGAGAGAACTAG +GGTTGGAGGAACTGGGGGACTCTAGGCTTGGATGAATATCAAGTCAGGGAGGCAGCTGTA +GGCAGGGGAGACACCTGGACTGGGAGCCCAGCCATTTAGCTGGGCCACGAGGCTTTCAGT +GAGGTTTCCGGCAGCTTTGAGTTGGCAGGATTGGGCCGGTTGTATGCCAGCCGTTTGGCC +TTTGTGACCACCACCTGAGGAGATACGGTTACTGGTCCTATTTACAGGTGAGGAAGCTGA +GGCTTGGGGATGTTAACCAGTTTGCCCAGTCCAAAGTGGTGGAGCCGGGAATTGAATCCA +CAGTTCCCTGAAATTGAGCCCGCATCTTCTGTACAACAGGGAAGATGAAAAAGACAGGTC +CTCTGGAGGCTTTCAGTAAACGTCGGCTGGATTCTGTTTACAAAGCTCAGAGTCAGGATC +TTTTATGGGGAGTGACATGGGCCTGGGGAAGGGGAGAGGCACTGAGCCAAGGTGGAGACA +GTGAGGCCTTCGCAGAGACCTCCCTTGTACCCACCCTGGTGTGGTCCCCATGAGCCTCGC +CTTGCTAACTGCTCGGTCTGCCAGGTGTCCCGGCTGGAGAGCTTTTGGGCACTCCGTGTG +GTGTGTCAGGAGCAGCTGACAGCCCTGCTTGCCTGGATCCGGGAACCATGGGAGGAGCTG +TTTTCCATCGGACTCCGGACAGTGATCCAAGAGGCGCTGGCCCTTGACCGATGAGGGTCC +CACGCTGACCTTGGCCCTGACCTCAGGAGCCACGCTGTAGACATTCCCTCTCCTGGTCTC +TGGGTCTGGCTTCCAGGCTCTGGCTGTGGATGTCTTCAGCCTCTGGGTGCTGGCCAGTGA +GGTCCCAAATGACCCAGGGCTTAAGGGAGAGGCGAGAGAATGATCTGGCCTCAGGGGACA +GGCCACCTGGTCAGGAGGAATATTTTTCCTGCACTTTTTCTCAGGTATCAATAAAGTTGT +TTCCAACTCATAGGTCATGTGTGGTACTTAGA diff --git a/test/csq/ENST00000295641/ENST00000295641.fa.fai b/test/csq/ENST00000295641/ENST00000295641.fa.fai new file mode 100644 index 0000000..5fec0a5 --- /dev/null +++ b/test/csq/ENST00000295641/ENST00000295641.fa.fai @@ -0,0 +1 @@ +2 18632 25 60 61 diff --git a/test/csq/ENST00000295641/ENST00000295641.gff b/test/csq/ENST00000295641/ENST00000295641.gff new file mode 100644 index 0000000..bbd5aa3 --- /dev/null +++ b/test/csq/ENST00000295641/ENST00000295641.gff @@ -0,0 +1,54 @@ +2 ensembl_havana gene 21 18612 . + . ID=gene:ENSG00000144589;Name=STK11IP;biotype=protein_coding;description=serine/threonine kinase 11 interacting protein [Source:HGNC Symbol%3BAcc:19184];gene_id=ENSG00000144589;logic_name=ensembl_havana_gene;version=16 +2 ensembl_havana transcript 35 18612 . + . ID=transcript:ENST00000295641;Parent=gene:ENSG00000144589;Name=STK11IP-201;biotype=protein_coding;ccdsid=CCDS46521.1;tag=basic;transcript_id=ENST00000295641;version=10 +2 ensembl five_prime_UTR 35 77 . + . Parent=transcript:ENST00000295641 +2 ensembl exon 35 84 . + . Parent=transcript:ENST00000295641;Name=ENSE00002345772;constitutive=0;ensembl_end_phase=1;ensembl_phase=-1;exon_id=ENSE00002345772;rank=1;version=1 +2 ensembl CDS 78 84 . + 0 ID=CDS:ENSP00000295641;Parent=transcript:ENST00000295641;protein_id=ENSP00000295641 +2 ensembl exon 255 341 . + . Parent=transcript:ENST00000295641;Name=ENSE00003482150;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00003482150;rank=2;version=1 +2 ensembl CDS 255 341 . + 2 ID=CDS:ENSP00000295641;Parent=transcript:ENST00000295641;protein_id=ENSP00000295641 +2 ensembl exon 3396 3601 . + . Parent=transcript:ENST00000295641;Name=ENSE00003658740;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00003658740;rank=3;version=1 +2 ensembl CDS 3396 3601 . + 2 ID=CDS:ENSP00000295641;Parent=transcript:ENST00000295641;protein_id=ENSP00000295641 +2 ensembl exon 3802 3876 . + . Parent=transcript:ENST00000295641;Name=ENSE00003678323;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003678323;rank=4;version=1 +2 ensembl CDS 3802 3876 . + 0 ID=CDS:ENSP00000295641;Parent=transcript:ENST00000295641;protein_id=ENSP00000295641 +2 ensembl exon 4149 4244 . + . Parent=transcript:ENST00000295641;Name=ENSE00003608784;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003608784;rank=5;version=1 +2 ensembl CDS 4149 4244 . + 0 ID=CDS:ENSP00000295641;Parent=transcript:ENST00000295641;protein_id=ENSP00000295641 +2 ensembl exon 4629 4736 . + . Parent=transcript:ENST00000295641;Name=ENSE00003635082;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003635082;rank=6;version=1 +2 ensembl CDS 4629 4736 . + 0 ID=CDS:ENSP00000295641;Parent=transcript:ENST00000295641;protein_id=ENSP00000295641 +2 ensembl exon 4866 4937 . + . Parent=transcript:ENST00000295641;Name=ENSE00003541596;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003541596;rank=7;version=1 +2 ensembl CDS 4866 4937 . + 0 ID=CDS:ENSP00000295641;Parent=transcript:ENST00000295641;protein_id=ENSP00000295641 +2 ensembl exon 7769 7895 . + . Parent=transcript:ENST00000295641;Name=ENSE00003554953;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00003554953;rank=8;version=1 +2 ensembl CDS 7769 7895 . + 0 ID=CDS:ENSP00000295641;Parent=transcript:ENST00000295641;protein_id=ENSP00000295641 +2 ensembl exon 8117 8220 . + . Parent=transcript:ENST00000295641;Name=ENSE00003545281;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00003545281;rank=9;version=1 +2 ensembl CDS 8117 8220 . + 2 ID=CDS:ENSP00000295641;Parent=transcript:ENST00000295641;protein_id=ENSP00000295641 +2 ensembl exon 8356 8451 . + . Parent=transcript:ENST00000295641;Name=ENSE00003571920;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003571920;rank=10;version=1 +2 ensembl CDS 8356 8451 . + 0 ID=CDS:ENSP00000295641;Parent=transcript:ENST00000295641;protein_id=ENSP00000295641 +2 ensembl exon 8637 8678 . + . Parent=transcript:ENST00000295641;Name=ENSE00003467019;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003467019;rank=11;version=1 +2 ensembl CDS 8637 8678 . + 0 ID=CDS:ENSP00000295641;Parent=transcript:ENST00000295641;protein_id=ENSP00000295641 +2 ensembl exon 8873 9019 . + . Parent=transcript:ENST00000295641;Name=ENSE00003558977;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003558977;rank=12;version=1 +2 ensembl CDS 8873 9019 . + 0 ID=CDS:ENSP00000295641;Parent=transcript:ENST00000295641;protein_id=ENSP00000295641 +2 ensembl exon 9214 9298 . + . Parent=transcript:ENST00000295641;Name=ENSE00003608694;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00003608694;rank=13;version=1 +2 ensembl CDS 9214 9298 . + 0 ID=CDS:ENSP00000295641;Parent=transcript:ENST00000295641;protein_id=ENSP00000295641 +2 ensembl exon 10208 10591 . + . Parent=transcript:ENST00000295641;Name=ENSE00003603489;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00003603489;rank=14;version=1 +2 ensembl CDS 10208 10591 . + 2 ID=CDS:ENSP00000295641;Parent=transcript:ENST00000295641;protein_id=ENSP00000295641 +2 ensembl exon 10744 10949 . + . Parent=transcript:ENST00000295641;Name=ENSE00003655116;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00003655116;rank=15;version=1 +2 ensembl CDS 10744 10949 . + 2 ID=CDS:ENSP00000295641;Parent=transcript:ENST00000295641;protein_id=ENSP00000295641 +2 ensembl exon 11258 11374 . + . Parent=transcript:ENST00000295641;Name=ENSE00003537785;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003537785;rank=16;version=1 +2 ensembl CDS 11258 11374 . + 0 ID=CDS:ENSP00000295641;Parent=transcript:ENST00000295641;protein_id=ENSP00000295641 +2 ensembl exon 11524 11701 . + . Parent=transcript:ENST00000295641;Name=ENSE00003107623;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00003107623;rank=17;version=1 +2 ensembl CDS 11524 11701 . + 0 ID=CDS:ENSP00000295641;Parent=transcript:ENST00000295641;protein_id=ENSP00000295641 +2 ensembl exon 13765 13995 . + . Parent=transcript:ENST00000295641;Name=ENSE00002387596;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00002387596;rank=18;version=1 +2 ensembl CDS 13765 13995 . + 2 ID=CDS:ENSP00000295641;Parent=transcript:ENST00000295641;protein_id=ENSP00000295641 +2 ensembl exon 14116 14219 . + . Parent=transcript:ENST00000295641;Name=ENSE00002356818;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00002356818;rank=19;version=1 +2 ensembl CDS 14116 14219 . + 2 ID=CDS:ENSP00000295641;Parent=transcript:ENST00000295641;protein_id=ENSP00000295641 +2 ensembl exon 15289 15386 . + . Parent=transcript:ENST00000295641;Name=ENSE00002425663;constitutive=0;ensembl_end_phase=2;ensembl_phase=0;exon_id=ENSE00002425663;rank=20;version=1 +2 ensembl CDS 15289 15386 . + 0 ID=CDS:ENSP00000295641;Parent=transcript:ENST00000295641;protein_id=ENSP00000295641 +2 ensembl exon 15913 16091 . + . Parent=transcript:ENST00000295641;Name=ENSE00003510227;constitutive=0;ensembl_end_phase=1;ensembl_phase=2;exon_id=ENSE00003510227;rank=21;version=1 +2 ensembl CDS 15913 16091 . + 1 ID=CDS:ENSP00000295641;Parent=transcript:ENST00000295641;protein_id=ENSP00000295641 +2 ensembl exon 16322 16403 . + . Parent=transcript:ENST00000295641;Name=ENSE00003460397;constitutive=0;ensembl_end_phase=2;ensembl_phase=1;exon_id=ENSE00003460397;rank=22;version=1 +2 ensembl CDS 16322 16403 . + 2 ID=CDS:ENSP00000295641;Parent=transcript:ENST00000295641;protein_id=ENSP00000295641 +2 ensembl exon 16637 16707 . + . Parent=transcript:ENST00000295641;Name=ENSE00002417904;constitutive=0;ensembl_end_phase=1;ensembl_phase=2;exon_id=ENSE00002417904;rank=23;version=1 +2 ensembl CDS 16637 16707 . + 1 ID=CDS:ENSP00000295641;Parent=transcript:ENST00000295641;protein_id=ENSP00000295641 +2 ensembl exon 17255 17502 . + . Parent=transcript:ENST00000295641;Name=ENSE00002415358;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00002415358;rank=24;version=1 +2 ensembl CDS 17255 17502 . + 2 ID=CDS:ENSP00000295641;Parent=transcript:ENST00000295641;protein_id=ENSP00000295641 +2 ensembl CDS 18205 18354 . + 0 ID=CDS:ENSP00000295641;Parent=transcript:ENST00000295641;protein_id=ENSP00000295641 +2 ensembl exon 18205 18612 . + . Parent=transcript:ENST00000295641;Name=ENSE00001461605;constitutive=0;ensembl_end_phase=-1;ensembl_phase=0;exon_id=ENSE00001461605;rank=25;version=1 +2 ensembl three_prime_UTR 18355 18612 . + . Parent=transcript:ENST00000295641 diff --git a/test/csq/ENST00000295641/not-a-start-lost.txt b/test/csq/ENST00000295641/not-a-start-lost.txt new file mode 100644 index 0000000..5f429c8 --- /dev/null +++ b/test/csq/ENST00000295641/not-a-start-lost.txt @@ -0,0 +1,3 @@ +79 G T missense|STK11IP|ENST00000295641|protein_coding|+|1R>1M|79G>T +79 G T missense|STK11IP|ENST00000295641|protein_coding|+|1R>1M|79G>T + diff --git a/test/csq/ENST00000295641/not-a-start-lost.txt-l b/test/csq/ENST00000295641/not-a-start-lost.txt-l new file mode 100644 index 0000000..5f429c8 --- /dev/null +++ b/test/csq/ENST00000295641/not-a-start-lost.txt-l @@ -0,0 +1,3 @@ +79 G T missense|STK11IP|ENST00000295641|protein_coding|+|1R>1M|79G>T +79 G T missense|STK11IP|ENST00000295641|protein_coding|+|1R>1M|79G>T + diff --git a/test/csq/ENST00000295641/not-a-start-lost.vcf b/test/csq/ENST00000295641/not-a-start-lost.vcf new file mode 100644 index 0000000..1f7fb8d --- /dev/null +++ b/test/csq/ENST00000295641/not-a-start-lost.vcf @@ -0,0 +1,6 @@ +##fileformat=VCFv4.2 +##contig= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO +2 79 . G T . . EXP=missense|STK11IP|ENST00000295641|protein_coding|+|1R>1M|79G>T;type=ENST00000295641:220462640-G-T diff --git a/test/csq/ENST00000301246/15bp-insert.txt b/test/csq/ENST00000301246/15bp-insert.txt new file mode 100644 index 0000000..4553f63 --- /dev/null +++ b/test/csq/ENST00000301246/15bp-insert.txt @@ -0,0 +1,3 @@ +770 G GAAGAAGGAGAAGGGC 3_prime_utr|C19orf33|ENST00000588605|protein_coding,inframe_insertion|C19orf33|ENST00000301246|protein_coding|+|89K>89KKKEKG|770G>GAAGAAGGAGAAGGGC +770 G GAAGAAGGAGAAGGGC 3_prime_utr|C19orf33|ENST00000588605|protein_coding,inframe_insertion|C19orf33|ENST00000301246|protein_coding|+|89K>89KKKEKG|770G>GAAGAAGGAGAAGGGC + diff --git a/test/csq/ENST00000301246/15bp-insert.vcf b/test/csq/ENST00000301246/15bp-insert.vcf new file mode 100644 index 0000000..cee36f2 --- /dev/null +++ b/test/csq/ENST00000301246/15bp-insert.vcf @@ -0,0 +1,7 @@ +##fileformat=VCFv4.2 +##contig= +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO +19 770 . G GAAGAAGGAGAAGGGC . . EXP=3_prime_utr|C19orf33|ENST00000588605|protein_coding,inframe_insertion|C19orf33|ENST00000301246|protein_coding|+|89K>89KKKEKG|770G>GAAGAAGGAGAAGGGC;type=ENST00000301246:38795550-G-GAAGAAGGAGAAGGGC diff --git a/test/csq/ENST00000301246/ENST00000301246.fa b/test/csq/ENST00000301246/ENST00000301246.fa new file mode 100644 index 0000000..005e076 --- /dev/null +++ b/test/csq/ENST00000301246/ENST00000301246.fa @@ -0,0 +1,16 @@ +>19 19:38794781-38795669 +GAGGTTGGGTGGGGCGTCTCAGCATTCCTCCAACGGGCAGGTCTCAGCGCTCCTCCCCCT +GCTCCGCTCCTCTGCAGGGCCCAGGCGCCCTTGGCCTTAGGACCCAACTTCTCTTACCGC +CATGGAGTTCGACCTGGGAGCAGGTGAGCTCCTGGGGAGTGTGGACTGGAGGTGCAGGGG +GCCGGACTCAAGCCCAGAAGCTGCCTGCACCAACCACCCAACTTCTCTCCACAGCCCTGG +AGCCCACCTCCCAGAAGCCCGGTGTGGGGGCGGGCCACGGGGGAGATCCCAAGCTCAGTC +CCCACAAAGTTCAGGGCCGGTCGGAGGCAGGGGCAGGTCCGGGTCCAAAGGTAAGTCGCC +TCATCACCGGCTGCGGAGGGGCGGGAAGGCTGGGGTTGCCCCTGACCCCAGGGTCCTGCC +TTAGGCCTCCAACTTCAGGGGGCTGGGTAAGGGGCGCCGCCTCACTGCCGCACCTCCATC +CAGCAAGGACACCACAGCTCTTCCGACTCCAGCAGCAGCTCCAGCGATTCGGACACGGAT +GTGAAGGTAAGGGGCTCTCGCCAGCGTCCCCAAGCACGTGCCCTGCACCCCAGAGAGGCG +TCCCCGCACTGGGGCTGGCGGGGAGGGTGCGGGGAGTGGTCCCCCTGTCTCGCTTCCAGC +CCAGAACCATCTCTTCTCTCCCATCCCTGCCCTCGGCCCCACAGTCCCACGCTGCTGGCT +CCAAGCAGCACGAGAGCATCCCGGGCAAGGCCAAGAAGCCCAAAGTGAAGAAGAAGGAGA +AGGGCAAGAAGGAGAAGGGCAAGAAGAAGGAGGCTCCCCACTGAAGGGCCCTGGACAGGG +CTCATTAAACCTTCCTCTCTGCCTTCTGCGACTGGTCAGCGTGGTGCCT diff --git a/test/csq/ENST00000301246/ENST00000301246.fa.fai b/test/csq/ENST00000301246/ENST00000301246.fa.fai new file mode 100644 index 0000000..77a8be0 --- /dev/null +++ b/test/csq/ENST00000301246/ENST00000301246.fa.fai @@ -0,0 +1 @@ +19 889 25 60 61 diff --git a/test/csq/ENST00000301246/ENST00000301246.gff b/test/csq/ENST00000301246/ENST00000301246.gff new file mode 100644 index 0000000..c6ef0e4 --- /dev/null +++ b/test/csq/ENST00000301246/ENST00000301246.gff @@ -0,0 +1,23 @@ +19 ensembl_havana gene 21 869 . + . ID=gene:ENSG00000167644;Name=C19orf33;biotype=protein_coding;description=chromosome 19 open reading frame 33 [Source:HGNC Symbol%3BAcc:16668];gene_id=ENSG00000167644;logic_name=ensembl_havana_gene;version=7 +19 ensembl_havana transcript 21 869 . + . ID=transcript:ENST00000301246;Parent=gene:ENSG00000167644;Name=C19orf33-001;biotype=protein_coding;ccdsid=CCDS12511.1;havana_transcript=OTTHUMT00000458168;havana_version=1;tag=basic;transcript_id=ENST00000301246;version=5 +19 ensembl_havana five_prime_UTR 21 121 . + . Parent=transcript:ENST00000301246 +19 ensembl_havana exon 21 143 . + . Parent=transcript:ENST00000301246;Name=ENSE00002964887;constitutive=0;ensembl_end_phase=1;ensembl_phase=-1;exon_id=ENSE00002964887;rank=1;version=1 +19 ensembl_havana CDS 122 143 . + 0 ID=CDS:ENSP00000301246;Parent=transcript:ENST00000301246;protein_id=ENSP00000301246 +19 ensembl_havana exon 235 350 . + . Parent=transcript:ENST00000301246;Name=ENSE00003679241;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00003679241;rank=2;version=1 +19 ensembl_havana CDS 235 350 . + 2 ID=CDS:ENSP00000301246;Parent=transcript:ENST00000301246;protein_id=ENSP00000301246 +19 ensembl_havana exon 484 546 . + . Parent=transcript:ENST00000301246;Name=ENSE00003669537;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003669537;rank=3;version=1 +19 ensembl_havana CDS 484 546 . + 0 ID=CDS:ENSP00000301246;Parent=transcript:ENST00000301246;protein_id=ENSP00000301246 +19 ensembl_havana CDS 705 824 . + 0 ID=CDS:ENSP00000301246;Parent=transcript:ENST00000301246;protein_id=ENSP00000301246 +19 ensembl_havana exon 705 869 . + . Parent=transcript:ENST00000301246;Name=ENSE00002868661;constitutive=0;ensembl_end_phase=-1;ensembl_phase=0;exon_id=ENSE00002868661;rank=4;version=1 +19 ensembl_havana three_prime_UTR 825 869 . + . Parent=transcript:ENST00000301246 +19 ensembl_havana transcript 24 866 . + . ID=transcript:ENST00000588605;Parent=gene:ENSG00000167644;Name=C19orf33-002;biotype=protein_coding;havana_transcript=OTTHUMT00000458169;havana_version=1;tag=basic;transcript_id=ENST00000588605;version=1 +19 havana five_prime_UTR 24 121 . + . Parent=transcript:ENST00000588605 +19 havana exon 24 143 . + . Parent=transcript:ENST00000588605;Name=ENSE00001309662;constitutive=0;ensembl_end_phase=1;ensembl_phase=-1;exon_id=ENSE00001309662;rank=1;version=3 +19 havana CDS 122 143 . + 0 ID=CDS:ENSP00000464940;Parent=transcript:ENST00000588605;protein_id=ENSP00000464940 +19 havana exon 235 350 . + . Parent=transcript:ENST00000588605;Name=ENSE00003679241;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00003679241;rank=2;version=1 +19 havana CDS 235 350 . + 2 ID=CDS:ENSP00000464940;Parent=transcript:ENST00000588605;protein_id=ENSP00000464940 +19 havana CDS 425 544 . + 0 ID=CDS:ENSP00000464940;Parent=transcript:ENST00000588605;protein_id=ENSP00000464940 +19 havana exon 425 546 . + . Parent=transcript:ENST00000588605;Name=ENSE00003656115;constitutive=0;ensembl_end_phase=-1;ensembl_phase=0;exon_id=ENSE00003656115;rank=3;version=1 +19 havana three_prime_UTR 545 546 . + . Parent=transcript:ENST00000588605 +19 havana exon 705 866 . + . Parent=transcript:ENST00000588605;Name=ENSE00001323608;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001323608;rank=4;version=4 +19 havana three_prime_UTR 705 866 . + . Parent=transcript:ENST00000588605 diff --git a/test/csq/ENST00000303039/ENST00000303039.fa b/test/csq/ENST00000303039/ENST00000303039.fa new file mode 100644 index 0000000..10644ad --- /dev/null +++ b/test/csq/ENST00000303039/ENST00000303039.fa @@ -0,0 +1,19 @@ +>11 11:56127691-56128764 +TCCCCCAAACAGATGAATTTCCAAACTCTGACATGGCTCCTGAAAATTTCACCAGAGTCA +CTGAGTTTATTCTTACAGGTGTCTCTAGCTGTCCAGAGCTCCAGATTCCCCTCTTCCTGG +TCTTTCTGGTGCTCTATGGGCTGACCATGGCAGGGAACCTGGGCATCATCACCCTCACCA +GTGTTGACTCTCGACTTCAAACCCCCATGTACTTTTTCCTGCAACATCTGGCTCTCATTA +ATCTTGGTAACTCTACTGTCATTGCCCCTAAAATGCTGATTAACTTTTTAGTAAAGAAGA +AAACTACCTCATTCTATGAATGTGCCACCCAACTGGGAGGGTTCTTGTTCTTTATTGTAT +CGGAGGTAATCATGCTGGCTTTGATGGCCTATGACCGCTATGTGGCTATTTGTAACCCTC +TGCTGTACATGGTGGTGGTGTCTCGGCGGCTCTGCCTCCTGCTGGTCTCCCTCACATACC +TCTATGGCTTTTCTACAGCTATTGTGGTTTCATCTTATGTATTCTCTGTGTCTTATTGCT +CTTCTAATATAATCAATCATTTTTACTGTGATAATGTTCCTCTGTTAGCATTATCTTGCT +CTGATACTTACTTACCAGAAACAGTTGTCTTTATATCTGCAGCAACAAATGTGGTTGGTT +CCTTGATTATAGTTCTAGTATCTTATTTCAATATTGTTTTGTCTATTTTAAAAATATGTT +CATCAGAAGGAAGGAAAAAAGCCTTTTCTACCTGTGCTTCACATATGATGGCAGTCACAA +TTTTTTATGGGACATTGCTATTCATGTATGTGCAGCCCCGAAGTAACCATTCACTGGATA +CTGATGATAAGATGGCTTCTGTGTTTTACACGTTGGTAATTCCTATGCTGAATCCCTTGA +TCTACAGCCTGAGGAATAAGGATGTGAAGACTGCTCTACAGAGATTCATGACAAATCTGT +GCTATTCCTTTAAAACAATGTAATTTTAAACAGTACAGGTAAATGAGGAGAGAGTTAATA +TAAGCTGCCATTATGTAAAAGAAAATGTAGGAAAAAGAAAAGGTAGGTAGCCGA diff --git a/test/csq/ENST00000303039/ENST00000303039.fa.fai b/test/csq/ENST00000303039/ENST00000303039.fa.fai new file mode 100644 index 0000000..03ceb4a --- /dev/null +++ b/test/csq/ENST00000303039/ENST00000303039.fa.fai @@ -0,0 +1 @@ +11 1074 25 60 61 diff --git a/test/csq/ENST00000303039/ENST00000303039.gff b/test/csq/ENST00000303039/ENST00000303039.gff new file mode 100644 index 0000000..4955f3b --- /dev/null +++ b/test/csq/ENST00000303039/ENST00000303039.gff @@ -0,0 +1,6 @@ +11 ensembl_havana gene 1 1074 . + . ID=gene:ENSG00000172487;Name=OR8J1;biotype=protein_coding;description=olfactory receptor%2C family 8%2C subfamily J%2C member 1 [Source:HGNC Symbol%3BAcc:14855];gene_id=ENSG00000172487;logic_name=ensembl_havana_gene;version=3 +11 ensembl_havana transcript 1 1074 . + . ID=transcript:ENST00000303039;Parent=gene:ENSG00000172487;Name=OR8J1-001;biotype=protein_coding;ccdsid=CCDS31529.1;havana_transcript=OTTHUMT00000391606;havana_version=2;tag=basic;transcript_id=ENST00000303039;version=3 +11 ensembl_havana five_prime_UTR 1 32 . + . Parent=transcript:ENST00000303039 +11 ensembl_havana exon 1 1074 . + . Parent=transcript:ENST00000303039;Name=ENSE00001172518;constitutive=1;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001172518;rank=1;version=3 +11 ensembl_havana CDS 33 983 . + 0 ID=CDS:ENSP00000304060;Parent=transcript:ENST00000303039;protein_id=ENSP00000304060 +11 ensembl_havana three_prime_UTR 984 1074 . + . Parent=transcript:ENST00000303039 diff --git a/test/csq/ENST00000303039/not-a-stop.txt b/test/csq/ENST00000303039/not-a-stop.txt new file mode 100644 index 0000000..78e4389 --- /dev/null +++ b/test/csq/ENST00000303039/not-a-stop.txt @@ -0,0 +1,3 @@ +983 A AT 3_prime_utr|OR8J1|ENST00000303039|protein_coding +983 A AT 3_prime_utr|OR8J1|ENST00000303039|protein_coding + diff --git a/test/csq/ENST00000303039/not-a-stop.txt-l b/test/csq/ENST00000303039/not-a-stop.txt-l new file mode 100644 index 0000000..78e4389 --- /dev/null +++ b/test/csq/ENST00000303039/not-a-stop.txt-l @@ -0,0 +1,3 @@ +983 A AT 3_prime_utr|OR8J1|ENST00000303039|protein_coding +983 A AT 3_prime_utr|OR8J1|ENST00000303039|protein_coding + diff --git a/test/csq/ENST00000303039/not-a-stop.vcf b/test/csq/ENST00000303039/not-a-stop.vcf new file mode 100644 index 0000000..b8fb814 --- /dev/null +++ b/test/csq/ENST00000303039/not-a-stop.vcf @@ -0,0 +1,6 @@ +##fileformat=VCFv4.2 +##contig= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO +11 983 . A AT . . EXP=3_prime_utr|OR8J1|ENST00000303039|protein_coding;type=ENST00000303039:56128673-A-AT, 983 is the last base of CDS diff --git a/test/csq/ENST00000318249/ENST00000318249.fa b/test/csq/ENST00000318249/ENST00000318249.fa new file mode 100644 index 0000000..0236bb5 --- /dev/null +++ b/test/csq/ENST00000318249/ENST00000318249.fa @@ -0,0 +1,749 @@ +>1 1:21766621-21811498 +GGCGCAGGCACAGGCGAGGGGTTGGGTGGCGGTTGAGACAGCGGCGGTACTGGGATGGGT +AGGTGAGGATCCCGAGACTGAGTGAGCTTCTGCGCGCGGTGCTTTTGGGAACGCGGGACT +GGCAACCTGCGGCGCCAGGAGCTGGGCCGAGGCGCGGCGGCGCGGCTGCGGGCCGCCGTC +TGGATGGGAAGTTACGGCGAAGTCCACCCAGCGTTTCTCAGGTGAGGGCGCCGCGCCAGG +CTGGACGGGCGGTGAATCCGGGACCGGCGGGCGCACACCTGGGTCGAGGCGCGGCCGTCG +CAAGTTTTGTTGCGCGAGCGCGGGGGCGGGTGGGAGGTGGGGGGTGTGGGGGGTCGTGCA +CCGCCGGGGGCTGAGTTCCCCGCGCTGGATTCTTCGCCTGCCGCTGCCGCCCTCAGCCCA +GCTCTCGTGGGCGCTGGGGAAGAAACTCGCTGGCGGGTGTTCTGTGGCATCCCAGGGGGT +GGAGGGACGGAGCAGCTTCGGGGGCACGTCCTCCTATATCCTGTAGAGGACACTGACTCC +GCACCCCACCCTCGAGGCCGGAAATCGGTTCCCTCTGCGGGCCTGAGAGGCGAGAGCGCT +CGCGCCCCTGACTTGCAAAGTTGGGGTCTTTACTGGCCTCCGGGCTTCTGCTCCTGGCGG +TGTCTCCAGGCTGGTGATGGGCAAGCCAGGTGTGCCAGGTCCAGGATGCACATGAGGAGC +GTTTGTAGCCATCACTGAATCACCTCCTGACTAGCGGGGCAAGCCTCAAATGAACCGCAG +GATTTCGGCTAGGTTGGATTGTGGGGTTGCTGTTTGCACTCCGAGGAGTTGCTGTGGTTT +CCCTGTGCCTGTCTGTCTGTCTTTCTGGCTTCTTAGATCATCATCTCATGTGGCGTCCTT +TCACCGAAGAGTTAACCAAGACGTTTGGCCTAGTTTCCTTGCTTTCCTTCTGTCTTTTGC +TGCTAGAGCTGCTTTCGAAAAGAAGTCTTTTCTGGCAGTGGTACCTTTTCTTTGGGTTAC +GGTGTTGTTCATCCTTTCTTTGCCAAAGGAATGAATCCCAGTGCTTCACGAAGTTAAAGA +TCTGCTGGTAGTGTTTAATCTGTTTGGAGCTGATATGCGTTAGTAGCTTTCTTTTTGTTT +TTAAATTTTATTAGTAAAATTTCACTAGTGAACCAGAAGCTATTTTTTTCTATTCTGAAA +TGCTGGCTTTAAGATTTCTGATAACTTTGCGTCAAAGAAATCTTGGAAAAGTTACTGAAG +TATACAGAAGAAGTTCACAATTTTAAATGTGCAGGGGGCCCGGGCGCAGTAGATCACACC +TGTAATCCCAGCACTTTGGGACGCCAAGGTGGGTAGATCACTTGAGCCCAGGATTTCCAC +ACTAGCCTCGGCAATGTGGCAAAACCCTATCTCTACTAAAAATACAAAAGTTAGCTGTGT +GTGGTGGTGTGTGCCTGTAGTCCCAGCTACCCGGTAGGCTGAGGTGGGAGGATCACCAGA +GCCCGGAAGGTTGAGATTGCAGTGAGCCGTGATCATGGCAGTGCACTCCGACCTGGATGG +CAGAGTGAGAGCCTATCTCAAAAAAAAAAAAAAAAAAAGTAATGAATTTTGACCAAGTGA +ACCACCACAGATCAAGAAATAGAACATTACTAGACTGGAGTATATTTTTGGAGTGGCATT +GTTGGTTTTAGAGGTATATGAATGATAAAACTTTAGTATTACATATTGTTGAACATTTTC +CCAAAGTGGTTGTACCATTTAGCAAGGATATTCTGGTTACCCCACATCCTCGCTGATGCC +TGTCAGTTAAAAATCATTTTGCCATTCTAGTAGGGGTGCAGTAATATATCAGTGTGGTTT +CATTGAGATTGAGTATCTTTTATTGCCATTTATGTGTCTTCTTTTGTGACATGCCTGTTA +AACCTTTTTATCCAGTTTTCATTGATATGCTTGTTTTCCTGTTGATTTGTAATACTTTAT +TCTGGATATGCCTCCTTTCTAGGATTTATATGTATTGCATTTCCCTTTTTTCAATCTGTA +GCTTGCGTTTTCACTCTTTTATGTTGTTTTTTCATGAATGGAGATTCTCTGTTTTTTTTC +TTTTTGAAACAGGATCTCACTCCATTGCCCAGGCTGGAGTGCAGTGGCACAATCACAGCT +CACTGCAACCTTGACCTCACAAGGCTCAGATGATCCCCCTGCCTCAGCCCCCAAGTAGCT +GGGACCTACAGGGGAGTACCACCACACTCAGCTGTTTTCTGTATTTTTAGTAGAGATGGG +GTTTTGCCACATTGCATAGGCTGGTCTGGAATTCCTAGGCTCAAGTGATACACCTGCTTC +GGCCTCCCAAAGGATTGGGATTACAGGCATGAGCCACTGCACCCGGCCTGAGATTCTTAA +TTTTAATGAAATTATACTTTATCAATCTTTTCCTTTATGGTTACTGCTTTTCATGTCATC +TTTAAGAAATCAATGCCTAACCTAAGAGTATGAACACATTTTTCTGTGTTAACCTTATAA +CAATTTTATTTCAGTTTTTGCATTTTTTTTTTTTCAGACAGGGCCTCACTCTATTGCCCA +GGCTAGAGTGTGGTGGCAGGATCTCAGCTCACTCAACCTCCATCTCCTGGCTCAAGTGAT +CCTCCCACCTCAGCCTCCTGAGTAGCTGCGACTATAGGCATGTGCCACCATGCCTGGCTA +ATTTTCGTATTTTTTGTAGAGATGGGGTTGCAACATGTTTCCCAGGTTGGTCTCGAACTC +TTGGGCTCAAGTAATCTGCCCGCTTCAGCCTCCCAGAGTGCTGGAATTACAGGTGTGAGC +CACCCCACCTGGCTATGATTCACTTTTTACTACATGGATGTGTCTGCTTTATCCAGGACC +ATTTATTGAAAAGACCATCCTTTTCCTTCTGCACCATGTGGCACTTTTCTTCATAAATCG +ATTGACTGTATGGTCATCTGATTTATGAAATTAGTGTGGGTCTGTTTCTGTTTCTGGACC +AACCTGGGTAACATAGTGAGATCCTGTCTCTACAAAAGATAAAAATAATAAATAAATGAA +TAAAATTTAAAAAATAAGTGCATAGAGCAGATGGAGTCATAGGTGATAATTTATAAATGA +TTGTCAGTTTCTTGGCTACATACAGGTGTTGGTAATTCAGATGTGTTGGGCGTTCAGGCA +AAATGTATTAAGTGAATTATATGGTGTTCAGAATGATTGCTAGAGGTTCACTGTGACTTC +AATTAGATGTTATTTGAGCCTCACAGAGCTGCAGTTTTGACTCTTTTATTTATTTGTCTT +TTTGAAGTTTTTACAATCTTCCTGTCAAGGCAGTAACACTTTTATACTTAATTGTTCTTA +GGTATACTTAATTAGCGAGAAAACTTTATGGATCATCCCTAAATAAGTGTTAAGCCATTT +AAAGGGCTCACGTGATGTGATATAAACAATAGTATTCTACATAATAGTTTTAGGACTACA +TAGAATAATTTTTTTTTTTTTCTTGAGACAGTGTCTCGCTCTGTTGCCCAGGCTGGAGTG +CAGTGGTATGATCATGGCTCTCTGCAGCCTTGATCTCTCAGGCTCAAGCAGTCCTCCCAC +CTCAGCCTCCTTAGTAGCTGGGTCTACAGGCATGCACCACTATGCCTGGCTAATTTTCTC +CTTTTTGTAGACAGGGTTTTCCTGTAGTGCCCAGACTGGTTTCAAACTCCTGGGCTGAAA +TGATCCTCCCACCTTGGCATCCCAAAGTGTTGGGATTACAAGCATGAGCCATCACACCTG +GCCATTTTAGTTTTAATAATTTTTATGTTTTTCTAATTTAAAAGATTTACTAAAATCTCT +TACGGCTGTTATTTATGAATATAGTATTCATTGTTGTTATTATGATGATTTTGTATGTGT +TCAATCTGATTTTCAATATAAGCTACCGGCAATTAGAGATTTTGTCTCTTTTATTCACCA +CTGTATTCTCAGTACTTGACCTTGCCTGGCATGAAACAGATATTGAATAAATATTTCTTA +AAAGAATGAATGAATGAACATACTAATACCATATTCAACAATCTCCAAGTATCACAGTTT +TCACCATCTAACAAATAAAATAGCTGTATAGAGTAGAGTCACAGTCAACCTGCCATGAAA +GGAAATGTCAATGAAAAATAAACCTTCGTATGTGTAGCTGCTAAGATTTTGGGGCTTTTG +TTACTGTAGTATAACCTAGCGAAAGCTCAGTGAGGCAGCATATACAATATATGTGTACAG +ATAGACCAGCTAGACCAGTAGATGAGATTCCAAAGATAGTTCAATAAGCATTAACTAACA +ACACCCACACTCTCTTAATTCCCTAACAAAAATAATGGAATTCTTGTTCACTAAGATCTG +CCTCAAATATTACTTTGTGAAAACTTCCCTGGCTACTCTAGTATTTAGTCAGGACTCTAT +TTTTTTTCCCGCCGGGCTGGAGTACAGTGGTGCCATCATAGCTCACTAACCTCTAACTCA +AGGCTCAAGGAATCCTCCTGCCTCAGCCTAAGGAATCCTCCTGCCTCAGCCTCCCGAGTA +GCTGGGACTACAAGTGTGTGCCACCATGCTCAGCTTATTTTTCATTTTTTATTTTCCAAG +ACGGGGTCTTACTATGTTGCCCAGGCTGGTCAGGACTGTTGATTACATATGACAGAAACC +CAACCACCTCTAGTTCCCACCACCTTTCAACCTGCTCTTCCCTGGGTCTTCCCAGTCTCC +GTAAATGGCAGCTCCATCCTTCAAGTTGCCGAAGCCCCAAATCTCAATGTTAACCTTGAT +TTCTCTCTTTTATCTCACAGGCAATCTGAAGGCAAATCCTGTTTAGACCCAGGCGAAGGT +TCCTGGTGACCCAGGCTCTCACCAGCCAATTGTCCCTTGCCGTCCTCCTGAGGGTATCTG +GAGCTTCAGTGCTGTGTGCTCTTGGCCTCCACACTGGGGATGCCACTGACTCCCACTGTC +CAGGGCTTCCAGTGGACTCTCCGAGGCCCTGATGTAGAAACTTCCCCATTCGGTGCACCA +AGAGCAGCCTCACATGGTGTGGGCCGACATCAAGAGCTGCGAGATCCAACAGGTAAAAAT +CCCGAGGCATTGCCAGCTCGGTGGGGTCAGAGAGTCCTCTTTCTATTATAACTCAGATGT +GAAGGGAAGATGTCAAGGTCCCTAAACATTGCAGGGCCTTGCCTGGCATGAAACAGATAT +TAAATACGTATTTGTTAAATGAATGAACAAATATCCACAGCCTGTGCCGCCCATGGCCTG +CAGTGCCGTGGTCAGGTGGAAGTGATTTTACTTCAGGAGAGGACAGTGTTCTCTCCAGGA +CTTTTCCTTACTAGCTAGATCTGCATCCCTCTCCCCGCTCTTCCCCTCTCACCCCCCATT +CTCTGCCCCCATTTCTCTCTGTTTCCACCCTACTGTCCCCTTTCACCTGCTTTCTGCTCT +TCAGCTTTGATGGCTCACCCCCTCCCTGTCCACCTGCATCCCCCAGGCTAAGGCTCCTAC +ACTGTCCTGGGTGGGGAGATGTGTCTCGTTTTAGGCAGTGCCCTCTGGATGTGTCTAGGA +TGGGGAAACATGGCTCAGTTGCCAGTATAATGGGTTAAAAGTGGCCACTTTTGAAGGCCT +TTCCCACCTCCCATTCCAGAATCCTGTAGGACTTAGAATTTATGGGCCACAGTGGAATTC +TTGGTTTCCCAGGACCTTGTGGTGGACACCTTCTTTCACTGAGCATTCATGGGGTGACTA +TTAGGTACCAGGCCCTGCTCTGGGCTAGAGGCCCCACAATGAGTAAATCTCAGGTCAGTA +CCCCACGGAACCCACCACTGCAGGCATTGAGAGGGGGAGAAAGAAAGGGGCATGGCCCGT +TTGTGTTCTCCTCATGTGGTCGCCCACAGGTCCTGGGGGAGTAGGAGCCAGTGCAAGGAG +AGAAGTCCAGTGAGAAAGGCAAATGGATGACATCAGACCCAGGGGCTGAGGTCCCCAGCT +GCAGCTGGGTAGCTTCTGGAGTGGACAGGGAGCAACAGGGAAGTTCGTGGCCTGGTGTTC +TGGGATGCATTGTCTCATCTCGTTCTTGTGAGCACCAGAACTTATCCAAAGACAAGACTC +AGTGTCTCTGGCAACAGTGGGCCAGAGACAGAATGTGTGAATTTCAGAGGAGGAGGAAGG +GGTTGTACCCCATGGAAACAGTATATGGTTTTACAGTAGCGCATCTTTCTCTAATAACTG +GTTAGTGTGTTCCTGTTAATGGAAAATATTGGTGGTGTAAGTTTCCCCACTGTTCTCATC +TTCATGTAAATTTGTTCATTTCCTTCCTTCCTTCCTTCCTTCCTTCCTTCCTTCCTTCCT +TCCTTCCCTACTTCCCTCCAACTCTCTTTCTCTTTATTCTTTCCCTGCCTCCCTCCCACC +CACCCTCCCTCCCTTTCTTCCTCCTTCCCTCCCTCCCTCCCTTCTTTCCTTTCTTCCTTT +CTTCTTTTCCTTTCTCTCTCATGCTCTTTTTCTTTCCTTTTTGTTCTCTCTACTTTTTTG +AAGAGATCACACTGTACTGAAACCTACATTATTTACCAAAATCTCCAGATCTGCTTCTGT +CTTGCAGGCAGAGAGCTCATCCAGTAGCCCTTAGCTCTTCCCAGCCCCCTCCTTTGATTT +GTGGGTGCCACTGGGGCAGCTGCTGAGTCTCAGTGGTTTCTAGTCTTCACCAAGTTCTGC +CCACCCAGATGGTTTTTACCTCTCCTTACCAGAAACCTGCACTGTCTAGATTGCTGAGGC +TGCTTCTCCTTAACCGATCTGCTATCTGTATTCCAGGGGCACCGCAGGGTTAGAGGTAAA +TGGCACAGGCCTTGAAATCTCCAACTGCTCTGACTCCAGGTTGGTGCACTTCAATGCCAA +GTACTAACCACCCAGTTACAGGATGCCACCAAAACCTTGATATGGGGCTGCTGCATCCTA +ATTAAAACAAATTAATAGAATTTTTTTTAGAACAGTTCTAGGTTTGTGGAAAACTTGAGT +GGATAGTACAGAGGGTTCTCCTAGGCTCCCCTGTCCTCCACACAATTTCTCCTATTAGTA +TGTTTTATGAGTGTGGTCCATTGGTTACAATTGATGAACCACTGTTGATACATCATTATC +CCCTAAAGTCCATAGTTTACATTAGAGTTCATTCTTTGAGTTTCACAGATTATGGGTTTT +GGCAATTACATAATGTCCTAAATCCCCAATACAGCGTCATGCGAAATAGTTTCACTGCTG +AAAATTCCCTGTGCGTCACCATTTCATGCGTCCTCCTCTCCTCCACCCCTGACAACCACT +CATCATTTTACTGCTTCTTTTTGACTTTCCAAGAATGTCCTAGAGTTGGAATGGTACAGG +ATGTGGGTTTCCAGACTGGCTTCTTTCTAGCATTATGTACTTTAAGTTCCTCCATGTCTT +TTCATGGCTTGATAGCTTGTTTTTTAAAATCAGTGAATCATATTTCGTTGTATGGCTACA +ACAGTTTCTTTATTCATTCACTTGGTGAAAGACATCTTGGGTACTTCCAAGTTTTGGCAA +TTATGAATAAAATTGCTGTAAGTACTTCTGTGCAGGATTTTGAGTGAACTTGTTTTCCAA +AGTGACAGTACCCTTTTGATTTCCACTAGCGATGGAAAGTTCTGGTTGCTCCTCATCTTT +GACAGCATTTGGTGTGTTCACCTTTTTGAATTTTAGCCATTCTAATACAGTGATATCTCA +TTGTTGTTTTAATATGCAATTCCCTAACGACAAATGATTTTGAGTGTCTTTTTCATATGC +ATATTTGCCATCTGTATATCTTATTAATGAGGTGTTCAGATCTTTCACCTATTTTTTTTT +CTTTGTGTTGTTTAGTTCTCAGAATTCTTCATATATTTTGGACAGCAGTTTTTCCATCAG +ATTATTTTGTAAATATTTTCTGCCAGTCTGTGACTTGCTTTTTCCATTCTCTTGACAGTG +TCTTTCACAGAGCAGAAGTTTTTAATTTTAATGAGGCTCAACTTAATTTTTTTCATTAGT +AGATTGTGCTTTTGGTTTTGTATCTAAGAAGCCATCATCCAACCCAAGATCCCCAAGATT +TTCTCTTATGTTATCTCCTAGGATTCTTATGGTTTTGCATCTTACATTTACATGTAAGAT +TTATTTTATAAAGGGTATAACATGCATACCTGGATTTATTATTATTTTTTTTTTTTGCAT +GTGTTTGTCCAGCTGTTCTAGCACCACTAGTTGGAAAGGCTGTCTTTGCTGTTTTAAATT +GTCTCTAAACCTTCATGGACGATCAGTGGACTGTCTGTAGGCCTGTTTCTGGGCTCTGTA +TTCCTTTTCCACGAATCTATTTGTGTGTGTTTTCTCTTTTCACCAACTTCACACTATTTG +GGTTACTGTAGCTTAATGTAAGTCCTGAAGTTGATAGTGCCAGACGTCAGGGGGGTTTTC +GGAACTTCATCATGAGAACCTGGTTGAGACCATTGTAGTAAAACTTGGAAACGTGTGAGA +TTCCCCCTTAGTCTGGTTTTCAAGGAGTTTTTAATGCTCTAGCCAGGCCACCCTCAGCTT +CTAGTAATCTGTCAATACCATTTAAGTGCTCCTCCCACTTGCTGTCCCCAGTAGCTTCTC +TTCCCTGTGAGCTCTGACTCCTTGTGTGTTAGCCTGTCTTTCTCATTTTTAGGGTGGCCG +TTTTCCCTGTGACCTCAATTCTCTGGTCCACCCTAGAAGGGTTGACTTTCAGTTTGTTCA +GCTTTTTTCTAGCTGTGAGGACAAGTGATGACTGCCTAGCTCTTTCCATGTTGGAATAGA +AACCCAAAAGTTCGTTTAAAGAATTACTTGTTATAAAAGTCAGCCATTGTCCACGTACAA +CTCAATGACTTAAGGTGATATATAGAATTGTGCAGCCATCAGCAGAGTTCTACTTTAGCA +CATTTTATCGCTTCCCCAAATTCCCTTGAACCTCTTTGTAGTCATTTCCTAATCCCTGGT +CCCCATGACTGGGTCTGAATAGAATAAATATTTGGAAAGCAGACTTCATTATATTTACAT +TTTCATGTGTTTGGGACTTTATATAGTGGACTATTGTGTTTGTTTTGTGACAAGCAGAGA +AGAGATTGCATTCTAGGGATGTTTTTTGGGGAACATAACAGTAGTCTTGTTTATGGCTCT +CCTTGAAATTGGTTCATCTGTGCTGGTGACTGGTATTTGCTACCAAACCTTGTCTGGTGA +GCACAAGAAAATGAATTTTTAAAAATCTGCTATGAAAATCGAGATGATACATTTTCACAT +AATAATATGTGGAGTTAAGTAACGAACCATCTTTATTTATTTATTTATTTATTTATTTTT +TGAGATGGAGATTTTGCTCTGTTCCTCAGGCTGGAATGTAATGGCGTGATCTAGCTCACT +GCAACCTCCACCTCCTGAGTTCAAGTGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGCGA +TTACAGGCACCTGCCACCACGCCTGGCTAATTTTTGTATTTTTAGTAGAGACATGGTTTC +TCCATGTTGGCCAGGTTGGTCTCTAACTCTTGACCTCAAGTGATCCACCTGCCTTAGCCT +CCCAAAGTGCTAGGATTACAGACATGAACCACGGCCTGACCTGAACCATTTTTATTCTTT +CAGAAATGTGATTGATAACAGTAAAGCCACACTCCTCGCATGCCTGAAATACCCCTCATT +GTCTTCTTCAGGTGGCAAGGGCTCTGAAACAGCCACATAAAGTTGAGGGCAATATTTTTA +CTGTAGTTCTTTCATTGATTGATTGATTGATTGATGGATTGATTGATTTTTTCTCTGAGA +GGAATTAGCATCCATGTATCTGAAATTGAAATTCAAGAGGAGAGACAGGCACCTGTACTA +GTTTTCTCTTGCTGCCAATTATCACATTACCACAAACCAGTGGTTTGAAACCACAGAAGT +CTGGAATGAAGCGGCTGGGTTCTCTGATCAGAGTCATGTGAGGCTAAAATTCAGAAATGG +GCTGGCTGTGTTTTTTTTCTAGAGCTCAAGCTATTTTTCCAAGTTCACTACAGATATTGA +AAGAGTTCCTATTCTTGTTTGTGGGGGACTGAGGGCCCTTTGTCTTTGCTGACTGTCAGC +CAGGAGACACTCTGACTCCAGAGGCAACCTGCTTTCCTCCTTACCTGTCTTTTCCATCAT +CAACCAATAACAACTCATGGAGTCCTTCTCAAGCTCCTGCCTTCTGTGGCTTCATCTTCT +CCAACCAGCCACAGAAAGCTCTGTCATGTATGGAGTGGTGTGATTAGATCCAGTTCATGC +AGGTAACCTCACCAGCTCAAAGTCATATAACTGGCATATAACATCATAATCACAGGAATG +CTGTCTCATCACCTTAACAGGCTTTAGAGACAAGGGTGTGACATATGTGGGGACCATTTC +AGAAATTCCATCTACCACAGTAGGACACTCACATTCCCCCAACTGCAAAATGCATTCACC +GTCTCCCCTAAGGTTCCCAAATTTCATGTCATTTAAAGCATTAGTTCAACATGAAAAATG +TCATGTAGATCACATCAGATCAAAAGTTTAAAATTCCATCTAAAACATCCACACCAGGTG +TGGTGAGGCTTCTGAGGGTGTCCACAAAGTACAGGTCTTTGACATAATTCCCTTACCTCC +GTCGACCTGTGAAACTGAACAAACAGCTTATCTGCCCCTAACGTGAAATGACGGGACAGA +CATAGAATAACAGCTACAGTGATTCTAGTTCAAAATGAGGGAACATGGAAGGGATAAAGA +AGTCAATGACCCAAAATAGTTTGGAAATGGAACTGGGCAAAATCCAGCAGAAGTTTCTTA +ATTAGGATCGACAGCCTGGGACCGGCCCGCCGTCCTATGGGTCTTTGCCTCTGGGCTCCC +TGCTCTGCATTTCTTGAAACCATTATTATTTATCTTTTTTCTCACACTCTTTTGCATATG +GCTTCTGTTGCACTCAAAATGTTTTTGAGATTCATCCATGTTGTTTTATGTGTCAACAGT +TTGTTCCTTTAGCCATTCCATGGAATGAATGTATCACAGTTTATTGGTCCATTCTTGTAT +TGACAGATACTTGAATGTTTCCAGTTTTTCATATTATGAATAAAACTGCTATGAACATTC +TTGTATAAATCATTTTCTGGACATATGTTTTAGTTTCTCTTGGATAAATGCTTAGGAATG +ACTGAGTCATAGAATAGGCAGTTGTTTGGTTCTGTAAGAATATGCCAGATATTTTCCCCA +AAGTGTTTATACTATTGTACATTCCATGCATTAATGTACGAAGATGAGAAAGCTTTTGCC +CCTTCCAAAGAGGCCTGTCTATATACATGTAATTTTTTCTAACTGGAGACAGGCTGATGA +CTTCAGGGACATGAACATGGGATACAGGACACCTGTCATCACCACCACCATGAAGTTGGG +ATTCAGGAAGGAGGTTAATCATATAAGGAATCCTGTGACCAGCATGAGCTTCTGTCAGGC +CACAAAGGGCACTCAAGTGAACAGGGCATAGTGGGTCCTGGGGTCATGGTGAGAAAGTGT +CTCTTTGGTAAAACCTTTTCCCTTGGGGAGGTAAATAAATTCTTGGTTCCTTCTTGGTAG +CCCTTGTAGATAAGGATGGTCAAATAAAATAATATTATATCTGTAAAAACTCAGATCTTG +GTAAGATTTACTAGTTGGGAATCCAGTGTTAATGCCATGAAGCAGCCGCCAGTTGGGATC +AAATGTGAGCCTATGGATCAAGGTGCATACTCAAACACAGAGAGCTTTTTTGAAAGATGC +CACCAGTAGTTTTTCCAGGGCAGAGATGGGTCGTTTATTTCTCTCTCTAATCTAGCCCAT +ATGCTAGCTGAGAAGGTTTCTTCATATCACTTTAAATGATGATGTCCTTGTACAACAATT +TTCTAAACATTCTTTAGATAAGAATTTAATGGGCATTCTTTATTGCATTAGGCTTAAATT +TCATGCATCTTAAGGTTTTATTGCAAAGTGTTGCCTTGCTTCCTTTTTAAGATGATACAA +TTTATAACACGCAAGTTTGCTGTCTGTCCCCTCCCTTTATATACATATAAAATGAGCAAA +CATGTGGCCATGAAACAGATGGTCATAGAATTGGTTCAGTGGTTGTGAGTTCAGCAACCC +AAGAGTGTCTTATCTGAAATACCACGAGGAATGCCTGGACACAGTAGACAAAGGTTGTTC +AACTGGATGCCTTAGGATACATGCTACCAAAAACAAAGTAGCTGAAAAGGAACCAGAATA +ACAGAATATCAGAGCCAGAGGAACATTTGGAGGTAATTCAGTACCTCCTCCTTTTCAACC +TACAGGGGAGATAGTGGAACAGAAGCAGAAATGGGCCTGCCTGCTGTGCCCAAAATTCAT +TGGAGATTATTGCGGTGAAGAATTTCATTTATGATGAAGGAGAATTAAATCCCCGTCAGT +TTAAATTCAGGCAGGTTTATTGAAAAGGTGAAGAAGCGTCTTGCAGAAGCAAAGCGTGGC +TGAGGCTTGTGGGCTTTGGGAAAATGAGCAGCTGACAGTGGCTGATGCTGCCCCTGACTC +TGGGACCATGTGGTCTCTTGTTCCCTGAGAGCATCTCTTCTATTCTCTTGCATCTTCCCT +CAGCCTGGCAGTCTCTGTATAATCTTCAACACATAATCGAGCAAGGCTGTGCCAGCCCCA +ATGCCACCTGGCACTTTAGGTCAAATTAGGAAGGCATGAAATAAACTGGCCCTTTATAAT +ACAGCTGTTGGAACCACAGTTGAAAGTACAATATCTTGACTCCTGGGTTAGTGCTTTATG +CTGAGCTTTTTTTTCTGAATATGAGCACAGACTTTGGAATATTAGTGTCACCTAGCGTTA +TTAGCTAGTATTCTCCTTTTGTTTCCCCATGACATCCCCTCCTTCTTCCCACAGATCCAC +TGTCCGCTCATTTCCATCCTGTCTCATGCCACTCGGGGCTCGTCCCTTCTAGAATGCATT +CCTGGCTCCCCTGCATGCACACTTCCAGTTAGGTTTAGCAATGGAGGGCACCTGATGGAG +CCTGGAAGTGAGAGGAAGGTGAGGTCTGTATTTCTTCCCTCTCCCTCCCTGCTCTGGCAC +TGAGTATCTGGCAATAGCTGCATCTGTCTATTACTTCAGTGGCCACTCTTCCACAGCCCC +AGTTCTCAGTGGGTCCCATAGCATTATTTACCTTTGTTCCTTTAGCTCCCATCAAGGAAG +ATCCAGAGACATTCTCCTTACCAAGACGTTAAGAAATGCACAGGTGAGGAGAACAGCGGC +ATGCGTGTAAAGGTCCTGTGGCACCCATCCTCTGCAGGCTGGAGGTCATGGCGGGAGATG +CTGCATGGATTTGCCCTCCCCGCTGTCAGTGAGAACAACAGGGTTCTGGAAGAGTAGAGG +ACAGGCCATGGGACTTGGCCATCTAGAGATAAGGCGGGAGGGATTTCCTTGAGAGGCAGG +GATATGTGGTGGTTACTAATCATTCGAATCATTGTGAGGTGTCTGGGAATGTAATGGATG +GGAAATCTACTAAGAAATCAACTTAGTAATAATTAGAAAAGCTCTAGTTCTGAGGACAGA +GACCTGATGGAGTCACCATAGTGGGAATTTATGACCTGGCATCCGGTTCAGATACCTGGA +GCTTCTTGAGTGAGGGAAGATTGGATCCCTTGAGGAAGAGTGAAGCCTTCAATGCTGCCA +CCAGTGTATGCTGTAAATCTTCCTCCAGGCCTTCCCCAGAAGGCCCTGAAGCCATTTATG +TGGGTGACTGAGGAAAGGGAAATACTCAGAGCTTCTGTGGCTTGTTGGATTCTGGCTCTG +AAGAATGCTAAACTAAGGGCACCTGTGGTGGCCATGAAAATGCACTACTTGCATCTCCAG +CTGCAGGAGGCCTAACGAATCAGCAGCCCCAGCTGCTACACTCCGAATGGAGGACTTGAT +GACATTTCCCCTGGATCTGCACTAGCCCATGAGGAGGAAAGCCTCCTATCAAGTCCTCCC +AGCAGAACACCCATGATGACTCATGAGGATGTTGAAAGTGTTTTCCTGTGTCAACTGTGA +CTTTCTTTCTTCAAAGTCTGTTTTGTTCCTGCACATTAACTGATTTATATCAAATAAGAG +AATAAATGCCTAGACTCCCATGAGTCTATCTTTTACTGATAAACTCAATAGTTCTGAGGA +CGGAAGCCTGATGGAGTCAGTATAGGGGGAATTTATAACCTGGCATCCAGTTCAGAGACT +TGGAGCTTCTTGACTGAGGGGAGATCGGGTCCCTTTGGGGAAGAAGGAAGCCTTCAATGT +TGTCACAAGTGTATCCTGGAAATCTTCCTCTAAGCCTTCCTAGAGAGACCTGATAATATG +ACTTATGATACAGTGACCCCAAATTCAGGGTGTTCTTGTCTACTCTCAAGAATGCAATAT +CTTCTTCCTCTGAATTGAACGTAGTACCAATATTTGTGTGTAGCTATGCACCTTAATAGA +CCATAGCTAATTAGATGAGGAATGGTAGACCCAATTCAACCATACAGGCGTCAACCATAT +CAGCATACAGGCATCCCTCTCCCACCGTTTCCTTCTTGTCCCCACTCCAAAGCCTTCTCC +ATTTTATTTGTATTAACTTTCTATTGCTGCATACTAAATTACTGCAAGCATTAGCGGCGT +AAAATAAGAATGATTTATTTTCTTGCAGTGTCCACAGATCAGAAGTTCAGGCCTGGATTC +GCTGGGTCTTCTTCTCAGGGCCTCACAGGCTGAAATTAGGCTGGGTTTCTTTCTGGAGGT +TCTGGGGAAGAACATCCTCTCAAGTTTCCTCAGGTTGTCAGCTGAGTTCAGTTCCTTGTG +ACTGTAGGACTGAGATCTCTGTTTTCTTGCTGGCTGTCAGCCAGGGGCCTCTCGCTGCTC +CTAGAGGCCTCCCATGTTCCCACTGCATGCTTCCTCCAGCCAGCAGAGGAGGATCGCCCT +GCATGGAAACCCTCCTGCACTTCACATCTCTCCAGGAAGTCCTCAGTCCCTCCAAGGAAC +TCACCTTCACTAGGTCAAGCTCATCAGATAATCTGTCTATCTTAAATTTGACCGATTTGG +GATCTCGATTACATCTGTTAACTTGTTTTTGCCATAAATTGTAACACAATCGCAGGAGTG +ACATCTCCTCAGTGGCTTTGTCTACACTCAGGAAGAAGTGATTATATAAGAGCAAAGATC +ACTGAGGGTCATCTTAGGATTCTGTCTACCATAATATTATAAAGACACAGTAATTAAAAG +AGTATAACAGATTTCTGCTTCTGTCTGTTAGAATAAATCATATCAGACTAACCCTGCCTC +CATAAACAACCGTAAAATTGTTTTCAGCAGTGTACGACAGGCAGTACAACAGAAAACTTA +AGGGGGAAGCCCCATGATTTCCTAGTTCTTTGGGGAGAATTTCTCAGCAGCTGCATAGTG +GGCTAGAGTCCACTCAGGGCAGGGCAGCCCACTGAGCTGAGAAGGCAGAGATCAGAGTTC +AAGACCATTGAAGCAACTGCAATCTGCAGGGCAGGGCACCAATGAGGAGACAGCTGATCA +AAGGTGCAGCTCTCAAAGTCTATGTGGGGTTCCATATGCATCCTTATCAAGGACTGGACT +GTACCTGCACAAGGAAAAGACTAACAGATTTAACAGAGGGGTGGCTGCTATAAAATTGAG +TTTGGACCAGAGGTACTTGAGGCGGAGGAGGGTTGGGGAATGTATGATGGAGTTTCTGCC +ATCCACGGTGGGAAGAACTCATGCACACCTCATTAGCACCCAGGTATCCAACTGAGACAC +TAGAATGGATGTGCTTTAGGAATAAGTGTCACACTTTTCAATAAGGCCTATTGTTCACCA +ACCTGGTAAAGCCTAAAGCCAAACCCTGACAAAATCCACAAAGGGGTGGATTGGTGATTG +AGTCCTGCCAAATTAGAGGGTCTTGGGAAATTCTGTGGGCTTTCCATGAATCCGTTGTAA +TAAAACATAAACCAGTCCACATAAGTCCAAAGTGATCGATCAGACAGTAATTTTACGCCC +ACTAGAGCAAAATTAATTCACACAATCAATGACACAAGTTAGCCAAGTCGACATTTAAGC +AAAATACATCTAAGAACAGCTAACAAATAACTCTCCTCAAACTCACATAGAGCATTCACC +AAGATAGACCACATATGCTGAGCCATCCTTAGTATTTTCTGTCCTTTCTCTTTGACTCGT +GTATACTGTGCTCAAACTCTTAAAATTATACACTTTAATTATATACTTTAATGATTATAC +ACTTTCATGCATCTCAATTGCATGTAAGTTATATTTCAATATATTTGTTAAAAGTTTATA +ATTAAAAAAACTGTCCTAGCTTGATTCCAGAAATCTTTTTTATATTTTAGAAAATGTAAT +GTTATATATTATCAGGGCAAAAGAGAAAAACCGTATGATTACCTTGTCATACACAGTAAA +AGCATTTGGCAAAATTGAAAAATTTTTCATGATTTATAAAAACAAACCCCAGAAAACTCA +GCATGATAAGAAGAGAAGGCAACACTTCCAACCCTATTAAGGGTAGATTTGAAAAAAACT +CACAGGTAACATTATATTAAATGGCATGGGATTGAATGCTTTTCTATTAAATCAGATAAA +AAAGTAGAATATCTGTTGTTATTCTTTCAATTCAGCATTATACTAGAGATCTAAATCAGT +GCAATAAAGTAAGAAAAATAAAAGTATTGAAAAGATTGAAAAGAAAGAATTGAGGCTGTC +TTTATTCACAGATAATGACTGTGTATGTTAATAATCCTAGAAATCTGCAAAAATCTGCCA +AAGCTAATTAGTGAGTTTGGTAATGTTGCAGAGTATAAGCTCAATAGAAGTAGTCTTTTG +TATTTCTGTGTATTAGCAATGAGCATTTGGAAAATGAAATAAAAATACAATTTCATTTCA +AGTAACTTCTAAATACATGTGCTTATAAATAAATTCAACAGGCTGGGTCTGGTGGCTCAC +GTGTGTGTGTGTGTGTGTGTGTATGTATGTGTGTGGGTGGGTGTGGGTGTGTATATTCAC +CTTTTTGAAGATTATCTATCGTTATCTCCAAACAGGGAACATTAAGAGAACATAAAAAGA +AACCACAATATAGGAGATATCATATTTATTTCCAACAAAGGGTTTTTAGAGTGTGTGTGT +GTATATATATATATATGTATGTATATATATGTATGTATATATATGTATGTATATATATGC +ATGTGTATATATATGTGTGTTTATATATGTCTAATAAGAAACAACACAATGAAACAATTT +CTCAAAAGACTTGAATAGATACTTCAGTAAAGAAGATACATAAATGGTCAATTAGCATAG +GAAAAGATGCTCTACTGTTTAGTCATCAGGGAGATCAATGAATACAACTTGATAGCAGTA +CATATCCAAGAGGATGGCTAAAATTAAAAAGGCTGAAAATAGCACATGTTGGTGAGGATA +TAAAGCACTTGGAAGTCTTATACTTGGAATGAAAAATGGTAGGACTCCTTTGAAAATCTA +ACAATGTCTTAAAGGTTAAACATATGCAAATCAGATGGACAGTCTTCCATTCCTAGGAAT +GTACACACTATGTGTGCACATGATCTGTATGTGTATTTCCAGACCAGACTGAGGGGTGGA +CTGCTATTTCTTGTGGCCCAGTAACGAGATGCAGATGAACTGGGGAGGAAGAGAGTTTTT +ACTTCTGCAACTGATTACAGGGAAAAGGCCTGGAAATTATCACCAGACCAAGTCAAAATT +ACAAAGTTTTCCTGAGCTTATATACCTTCTAAGCTATATGTGTATGTGGAAGTGTGCATT +CATCTAAATACAGAAGTGATTAAGTTCTTCTAATCTATAACTAAGGTCTGAGTCCTGAAG +ACCTTCCTCTGGAGCCTCAGTAAATTCACTTAATCTAAATGGGTCTAGGTGCTGGGCACC +CTTATCTTGTCTCCTGCTAAATCACAGAGGTTTGGGGAGTTCCTTCAGACCTCCAATAAA +CTTGTTTGTGGAGGCCTGGGGAGTTTCTTCAGACCCCCAATAAAACTTGTTTAATACTAA +ATGACTCCTGTTAAGAATGTCTTCGTTATTTTGTCATGCTTTAAGGCCCAGGAAAAGCCC +AGGCAAAGCTCTTGGTGGGCTTTGGTTACATTCCAGCCTTTGTAATAAGGGCATGGGCTT +TTTTTTTTTTTTTTTCCTCTTAATATTTAACTGAACCACTCAGTCGGTACTGAAACAGTT +GTTAGGGAGGCCTGTGTTAGTGAGACCTGGCCTGCCACGTATGGATGCTCATGATAGTTT +CTTCATAATAGCCCAAACGTGGAATGATAGAAATGTCCAATAACAAGTGAAAGTATGAAC +AAACACAGTATAGCCACACAAAGGAATACTACTCAGCAATTACAAGGCATTAACCGTTGA +TGCAAATACTCATATGGATGGATTTTAAAATTATGTTGATGCATGAAAGAAGGCAGACAC +AAAAGAATACGGGTACAATTTCATTTATAGAAAATGGTTAAAAATGGAAACAGACCTGAA +GTGACAGCGGCTCCTTGAGGCCGAGGGCTGAAAGACTGATGAACTGCAAAGGGGTACAAG +AAACTTTGGGGCGTAGGGAAATTCCTCTATCTTGGTTGTGGCAGTAGTTCCATTAGTGTA +TACATTTGTAAACATGCATTGAATTACACATTTTAAAGTGGTGCAGTCTGTTGTACCTAA +ATGATGCCTTTATAACATTGATTTCATCATCTTAATTTCTCCATACTAGCAATTAGCAGC +TAGAAAATGAAATTCAGTAAAACATAATCGAGATTAATAGTCAGAATCATTACATGCTTA +AGAATACATGCAATGAAGCGGGTACAAGGCCCGTAAAAGCAATTGGTGAGAAAAATTAAA +GAAGACTAAATAGAGAAATATATATCATGTTCATTGATTGGAAGATTCAATTTTGTTAGC +ATATTACCTCAACAGAATTCTGATTAATATTTCTAGTAGGAGATTTTAGAGAAATGTAAA +AGCTAATTTCAAAATATATTTGAAAATCCAAGAACCTAGAATAGGCAAGTCGGTCTTGAA +GAAGCAGTAAGTTGGAGGACTTACTCTGCTAGACTTCAAACCTGATTTAAAAGCTACAGT +AATTTAAAATGGTAGTACTGGTGTAAGTATTCATAAATATATCAAAGTAAAAGAATACAG +ATTCAAACAATATGACCACATATGTAGTTATTTATTTTAGTAGAATCTTTTTTATTCATA +AAAAATCCCTCCAAAACGTTTTCCAAGAACACACAGGAGGGCTATGGGTAGAGGAAGGTG +TCTGTCCATCTATCCCTGGCCCCCAGCCCATGTGGTTTTGGCAGCAATAGGGGTGTGGGG +TAATGTCCCCCAAAATTAAAATGGTATATGTGTGTATGAGAAGGAAAGGGGGGCAAAGCT +GTGGGGAACGGTTGAGGGGAAGGAACAAAGGAGGTCAGTACTGGGAACGCTGAAGATGGG +AGGCCATTTCATAACATTTCTTGTTGATGAAACTGCCATGGACAGCTTCTTTGCTCATCA +GCAGGCCCAGTGTCTTGGCAATCATGGTGACAGTGACATTGAAGGTGGGGGCTCCACCGA +TGCTCTTCGTTTGAAGATGCACGGTCAGTTCCCCATCCTGCAGCAGTGAGTCCAGGACCA +CAGTACATTTCTGGCCCCGCAGTGTCAGCCTATTCACGAAAAAGCTTGACCAGTCTTTGC +CAACCAGGACACCAACCTTAGCTGGCGTGATGTTCACGAAGGTTTTTCCCTGGGACGGCG +GCCCAGATGGAGGGTGAGTCCTTGTTGCCCACGATGGCCGCGAACCTAACAGGTCCCATC +CGCCACGAGGCTGTAGATAGAGGCGTCCACCTGGCCGTTGCGCGGCTGCGGGGGCTCCTC +TGGTCGCTGCTGCTGGGGCCGCCTGGGCTGGCGGGCAGGGGAGGCGGAGAGCTGCGTGCA +GGCACTGCCGTCCTCACCACGGCTCTGCTGGCTGTGCAGTGGCCCTCGCACCGCCATATA +TATATATTTATTATACTTTAAGTTCTAGGATACTTGTGCACAACGTGCAGGTTTGTTACA +TAGGTGTACATGTGCCATGTTGGTTTGCTGCACCCATTAACTCGTCATTTACATTCGGTA +TTTCTCCTAATGCTATCCCTCCTCCAGCCCCCAACCCCAGGGACAGGCCGTGGTGTGTGA +TGTTCCCCGCCCTGTGTCCAAGTGTTCTCATTGTTCAGTTCCCATCCATGAGTGAGAACG +TGCTCACGCTGCTACTTCTAAATGTTTTAAAAACAAAGACACCAATGCTCTTCATTGAGG +AAATGGAAGACTTTTAAGTAAAAGGATTTTGAGTGAAATAATATTTGTGGTTTTAAAAAG +TTAATATTAACCACTCTTCATCATACACTGAAATTAACTTAAGATGTGAAAGTTAAAATT +AGAAACCTTGTAAAGGAAAAATAGGAACTAATTTCGTGGACTTGACACAGGAAAATGTTT +CTTAGACTAGATACTGTAACACTCACCACAATAAGAAATCAAGCAAATTGCCCTTCATTT +TTAAAAACCTTCTGCTTATTATGTTGTTGTTTAACAACTTAAAAGCTATCTGTAGACCAG +GAATAGCAAATAATTATTTGCTATATAATATAGCAAAAAATGTGTATATATAAATGGATG +CATTCAAAATATATAAAGAACTCCTATAGGTTACAAGAAAATGACAAACACACCAGTGTT +TCAATGAACATAAAATTTTGAGAAGATATTTTCCATAAGAAGATATCTTACTGAACATTA +GGCATGAGAAAACCAAAACAGGATATCACTACCCACCTAGTAGAATGGCTATAATTTAAA +AGACTGAAAATATTAAGTGTGTGGGAATGTAGAGCAACTGGAAATGGCCTACATCTTTCA +TAGAAATGTAAAATAATACAATGACTTTGCAAAGCTCTGTGTCCATTTTCTTCCCATTCA +CCAAGCAACTCCATCCGTAGCTATAGAGACCCAGGAAAATCAGTATGTCCATTCACAGAA +ATAATTATATGAGAATATTCATAGTTACTTACGCACAGTAGCCAACAAGTAAACCTGTCT +CCCGTCAGAAAAATGGATATCAAATTGTGTGATAATCATACAAACAATAGGATATTACTT +GGCCAAACAAAACGAAACAAGGGAAAAACACAGTCAAACAAATTAGTGGCATATATAAGC +ACCTGAGTAGGAGAAGTCAAAACAAGAGGAAGTACTAAATGATTCCTTTTTTTAATTTTT +TTGAGATGGAGTCTCACTCTGTCCCCCAGTCTGGAGTGCAGTGGCACGATCTCGGCTCTG +CCTCCCAGGTTCAAAAAATTTTCCCTGCCTCAGCCTTCCAAGTAGCTGGGATTACAGGCA +CCTGCCACCATGCCTGGCTAATTTTTTGTATTTTCAGTAGAGGCAGGGTTTTACCATGTT +GGCCAGGCTGGTCTTGAACGCCTGACCTCAGGTGATCTGCCCGCCTCAGCCTTGCAAAGT +CTTGGGATTACAGGCATGAGCCACCAGGCCCAGCCAAAATGATTCCATGTTTATGAAGCA +CATGATCAAGCAAAATGAATCTATGGTGGCTGCTAAGTTTAAATATTGGTCCCCTCCAAA +TCACATGTTTAAATGTGGTCCCCAGTGTCGGAGGTGGGGGTAAATGGGAGGTGTTTGGGT +CATGGGAGTGGATCCCTCATGAATAGATGAATCCCCACCCTGGGAGAAGGTAGTGAGTGA +ATTCTCACTCTCTTAGTTCCTGTAGGAGCTGGTTATTAAAAAGTGCCTCTCACCTTTCCT +TGCTCTCTTTTGCTTCCTCTCTCGCCATATGATCTCTGCACACCCTGGTTCCTTTTCACC +TTCTGCTGCAAGTGGAAGCAGCCTCAGGCCCTCATTAGGAGCAGATGCGGGGGCCATGCT +TCTTGTACAGCCTGCAGAACTATGAGCAAAAGGCACCTCTTGTCTTGATAAATTACGCAG +CCGCCGGTATTCCTTTCCAGCAACACAAAGGGGCTAAGGCGGTGACAACATTCAGAATAT +ATTCTTCATTTGGGGAATGAGTATTGACTGGCAAGGACCACATCAGAACTCTGTGGCATG +GGGGAAAATGTTCTCTGTCTTTAACTGGGTGTTACTTTACAATTATAATTATATTAAAAT +TTATTAAGCTGTGCCTTTAGGTTTTTTGCAGTATACTCTATGCAAATTTTACCTCAGTGA +AGAACTGTTAGCATACAACAGAGAGATAACAAACACTCAAAAATTGAAAATTGATGGAAA +GTAGATAACAAATATTTAGCCTAGAAATAAGAGGGATCCATTGAGAAGAAACCAAAAGCA +ATGGAATAGAACAAAGACAAAAAAGTATAATAAAAAGAGTTTTAAATTTCAAAGTTTGAA +ATGATATTCAAGTGACACACTGTTTCCTTGGGAAAATCAAGTGAGAACCACAACTCTGAG +ACTAATTCCAGCAAAAATATGTGAATCAGTTTGATCTAATGGTACAAGGTTAGCTTTGAA +GGCCAAAAGGAACTGGTTTCTAATTCTTATTCCTCTCCTCACTAGTTTTGTGACCTAGGG +AAATTTTGCAATCTTTCTGAGTTTGTTTTCTCATCAGGAACAGGATACTACCTAAGTAAC +AGGATAGTTGATAGATTTAAATATGATCGCATGGCAGTGGACATGAGCCATAATTAGTTG +CTAAGAATATATTGACACTGAACTCTCCTTTATCCATGTTAAAATTGTAGATAAACAACA +ATTGACAAAGAATAGACAAAATATTCTAACATAAATATTCTTCCCTTGTTTCTAGAAAGA +AGTCACACATACAGTAAAAATAATTAGAGAGGACCTAGTTCATATTGAGCAATCTTCCCC +AAACCCTGAAACAGGTCTTCTTTCTAACACCAGAGGTATCTTGAGTGAGTCCAACCCCTG +CAGTCCCCTCTGTCTGGAATAGATGGAGGAAGTTTGCTCCAGCCTTAGAACAGCATGGGC +TGGCAAGCGTTCTCAGAGAGGTCTCGACTTCAACTCTAAAGGGCCTGAGGAATATGTGCA +ACTGGGTCGGGTTAAGGCCAAGCTGAATCACATGACCAGGGCTCTCACCAGCGCCAAAGT +CAGTGGAAGGATATCAGTCCCCAGAGCTCTGTCACAGGCCATGGATGCTCCATGGAGGGG +TGGTGAGCATATGAATAAGAATCAGGAGAAACATCGGTAATGGACAGGAGGCATAAATAA +ACAATGTCCACCGTCCTCTAAAACCCAGGAAAGTTCTCATTCAAAAGACGATGTCTTGAA +GGAAACATAGGTACAAATCTTTGTGACTTTGGATTAGACATTTTTTAAGTAGGCACAAAC +AACCGAAAAATAGATAAATGGACTTCATTAAAATAAAAAACTTATATGCTTCAAAGGACA +CTGTCAAGGAAGTGAAAAGATAATCCACATAATGGGAGAACTATTTCCAAATTATATGTT +TGACACAGGTCTAGTACCTAGAGTATATAAGGAATTCATATAACTGAGCAATAAACGACA +ACCACATTTAACAATGGGGAAAAAAGCTGTGAGTAGAGGTTTCTCTAAAGGAAACACTCA +AATGGCCAAGAAGCACATGCAAAGATGTTCAATGTTTTTCGTCATTAGGAAAATGTAAAT +TTAAACCAAAATGAGATACCACTTCACACCCAGCAGTATGACTTAAGAAAAAAATAAAGA +CAACACATGTTTCAAAAGTGATGGAGAATATCGAATTCTCATATATTACTATTGGGAATC +TAAAATGATGTAGCTACTGAAGTTAGTAAACAGTGTGTGAGTTCCTCAAAAAGTTAAACA +TAAAAAAAGTTAAACATAAAGTGACATATGATGCAGCAATTGCACTCCTAGGTTTATAAC +CAAGAAAATGAAAAACAGGTGTTCACTCAAAAACCTGTACAAAGCTGTTCACAGCAGCAT +TATTCATAATAGTTAAAAAGTGGAAACATCTTTAACCACCATCAGTTGATGAATAAACAA +AATGTGGTATAACCATATAGTGGAATATTATCTGGCCATAAAAAGTTGAAGTACTGATGC +AGGCTAGAAAGGATGAAACTTGAGAACAATATTCTAAGAAGCAGATAGAAAATACCACAC +TTTGTTATTCCATATAGAGGAAGTGCCCAGAACAAGTACATCAATATATAGAGAAGGTAG +ATTAGTGGTTGTCAGAGAGCACAAGAGGGGGGGAATTGGAGAGTGTCTGCCCATAGGTAC +AGGCATGCTTTTTGGCATTATGAAAATATTCTGGAATTAGGTAGTGGCGATGGTTGTGAA +AGTTTTGGAATATGGTAAAAGACACTGAAATGTATGCTTAAAAATGGTGAATTTTGTGAT +GTATAAATTCTACTGTAGAAATAATAATAACAACAAAAGTAATAAAGCAAGGTGTCTTTC +CACATCTCCATGTCCAGTATTTTCATTAAAAAAAAAAAAGAAAGTAAAAGCATTTCAGGG +CCAGGTTCAGTGGCTAACTTCTGTAATCCCAGCACTTTTGGAGAACTAGGTGGAAGGATC +GCTTGAGGCCAGAAGTTCAAAACCAGCCTGAGCAACATAGCAAGACCTTGTCTCTATGAA +AAATAAAAAATTAGCCAGAAATGGTGATGTGTGCCTAGAGTTCCAACTACTTGGAAAGCT +GAGGCAGGAGGATCGCTTGAGCCCAGAAGTTCAAGGTTGCCGTGATCTATAATCACCAGT +GCACTCCAGCCTGGGTGACAGAATAAGACCCTGTCTCAAAAAAAAAAAAAAAAAAAAAAA +AGCATCTCACTTTAATAGTAAGTGGCCAAAATATGATGCTGGCTGCATGTTGTGAGGAAA +TGTGTTAGATGAAAGAAGTTAAATTCCAGAAGATTTCCTTTTTTCAGAAATGAGGTATAG +GGGAGAGAAGCACTGGTCCACCTGAGATCTGGCTCCAGGACTTACAACAAGGGGAACTTG +GGCAAGTTACAGACTCTGTGTGCCTCCATTTCTTCATCAGCAAAACAGAAAGAATCATCC +CATAAACTGTAAGGTCAATGCTGTCAGTGAGTCCCCAAATTGACTGCACATCTGAGTCAT +ATTAACAAACACATTCCAGGCCCCACCTGAGCCCTCTGAATCAGAATCCCTGCAAGGAGG +ACAATGAACTTGTATTTGCACTGACTTTCCCAGCTGTTTCTTACTTTGATCAACTTGGGG +GTGGGACCCATTGAGCTGCATCACATCATTCCAAAGCCAAAACACAACAGCAGAACAAGA +ATATTTTCAATGCAGTCTCTGAAGCAGAGGAGAAACTTTTGAGGGAACCTAGAAGTAAAG +GACATCTGGCTTGCTGGGCTCCATTTAAACTTTGAGTATAGCAGAGACACGAGCCCTTCG +GGACACATGCCTGTCGCAGTGACACTCCAACTTCGGAAGAGTGGAAGCCCTAATTCCAAA +TTCAAGCATGCTTTGAGTAGAAATGAAGTTTGCCTCTTTTTGCACAGGAAGATGGCCAAT +CTTTCCTAAGCTGCTGACCTTACAAGAAAAAGAATCGTACTGCTAAGAATTCAAACTTCA +GCAGTCATGGGTGAGTAAGGAAGTCTTATAAATGTATTTTAGCCACCTAACAAGAAACTA +GAAATTTAGCAAGTTCTTTCACATTCAGGACAGTTGTGTTCACTAGATCAGAGGCACTGA +GACATGAAGAACAGACCCCTAAAAAGGGAAAGTGTTCCTTTCAGTTTTAGGACACCACTG +GAATATTAGGGAAGTGGAAACACAGCTGCCCACTCTACAGTATGGGTTGCCTTTGTGTCC +GGAATGTGCCTAACGTCCTGACCTCCATGCCCTTTTCAGGGAGCCTTGGGAGGAGCCCGA +ATCACTGATGGAATCGGACAGTGCATGGAGATGGTTCAGCAGGACGAGGGTAAGTGCAGG +GGCAAGTCCAGGTCATACTGAGAGACAACGAGTGGCGCTGACAAGAGACAGACAAAGATA +AAATCAAAAGTTTGTGCTTCATCTTCAAAAATCCAAACTAATAACACACTTGGCCTTATG +AGAAATAATAAGTATTTTTCTATTTACATGAGAATTTAATCTCAAAACAGGAATCAGAAA +TATATTAAGTCCAGGGCATAAAACCTAAACCACTGCTCATATTTATTCTTTCTAAATAGA +GCAAAGTGTAAAATCTTCTCCATAAAATGCACATTGTGCTTATGAAAAGGCCAAAGTCTT +AGTGAGAATCATTGGTATTCCATAGAAGAGTGAATTAAACACAGCCAAGGGAAGACCCAA +GTCTCATACTTCTCTTGTATATTCCAGAGTTCCAGGGGAATTCCAGGTGATAGAGGTGAT +CTCCCATACTGTTAAAGCAAGGTTGCAGACACTTGGGAATTTTGGTCCCAGTACTCTAGG +AGGTCACACCTCTGTCCTGGACAATACTACAGGAATGTATACTCTTCCTATGACTCATTC +TGGTCATTCTTCCAGCATCACAAAAACCAAAAAAAAAAAGGAAATATGTCCAAATACATG +ATTTGCTATCCCTCCTCTTCAAGTTTCTTACCTGTTACTTACGGATAATAGCATTACCAC +AGGATTATGATGAAGATACAATGTCCAAATGTAAGCACAGTTTTGAGCAAAATGCCTTGT +ACGAATTGGTCAGTGAACAACTGGTAAATAATTATGTGAATATTTACTGAATTATATGGA +TCCTATGAATAATTACTGAATAATTACTGTGATTGCTTTTATTGGCAGTGCTGAAAACTC +ACCCCTGTGTGACCTCAAGTAAGCCACGTAACTCTGTGAACCTGCAGTTTTATCATTTTT +AAAATAAAGAAACATGACAGATTTTCATTATGACACAGAATGTCAGGTCTCCCAGATGCC +AGAAAATACATTTACTTAAAGCCGTTGATACGTCTTAAAGCGGTTTCCTTACAGTGTCAT +TGGAGGACAGCGTGGAGTGCAGAGAGACATGCTTTGAAATGGGATTGATCCAGTCCTCCT +TCCTTCACTACCACATGAATGCTGGGCAGCCCAGGATCACACTCACTGCACCCTCAACTC +AGGCAAGTCCAGCAGCCAATCTTAGGAGACCTGGGCTACAGAACAGTCTCCCAAGTTCCA +GGCTCACAAAACCTAGGTGGGGATGAAAGCTGAGAAAGTGAGGAGGTGGTTCAGGGGATC +ACTCTTTCCTACTCATTCCTCTCATCTCAAACTCACCCTCTACTGCAACACTGAGGATCA +CCAACCAACCGTGACCATAACCTTGATCTTGCCATGTTCTGTTAGTGGAATGAAACCAAA +AATCAATGGTGTTAGTCCAACCCAACGAAATAGATATCAAACCACATTCCATAAGAACCG +CCGCTCATGGCCCTGTTCTTTTCAGTATATGGGAAAACAAAATGGAAACAACAAAATAGC +ATCAGGTTTATGAAACTTCCCAAGATAGATGGTCACACATGTGTTCAGGAGATCTCTATA +TAAATGATTTTGGTCACTTGATACCTTGAAAAGAGCTCTTGTGATACTAGAATGACATCC +ATAAGTGACGAGTATAAAATGTAGCGCTCAGTGACATCAAAAACCAAATCAACCCACATA +GAGGAAGAGCTCTGGACATAGGGATGTCAAACTGGTCTAGAGTGTAATGAAAAGCAAAGA +TGGTGCCCCAGTGAGAAAAAAGAAATCAACGTAACAATGGGAATCAGCAAGAAGAATACT +GAGACAGGAAAGACAACATTTTTTACAAATGAGTTATTCATTCACTTTCTAGTGGATACA +GACAAAACTGCAGAAGACCCAGAGGAAATCAGGGCAGGCTAAAAGTTTGATATCTTACAC +TTGTGGAAAAGCCTTAAGATCTGTTTTAACTGAGAGCAGGTGGGGTGACTTCATGACTAC +CGTTAAGAAAATATAACCTGTTGGGAAACTGGTTCTGCCTGGATGGTGTTGTACAAACAA +GCGATAAACAATGAGGAATGTGCTTAGATGTATTGGGAAAGAGATGGGTCTGTGGCATTG +TCACAAGGGTACACGAACACTGAGAGTGAATTTTAGAGGAATGATCCCCATTGGTGGTGA +CCCTCAGGTGAGACGAGGGTGCCTGTGTTTCAGCAAAGCCTGGGCAATTGGAATGCAGGG +CTCCTAAGATTCCATGACACCCCCACCTTCTAATTCTGTTATTGCAACTGCAGACCGTTA +CCTGGCACACTGGCCTCACTCTTGTCGGAGACTGAGCTATTGGCAGTGCCTTCAGCTCTG +AGCTCAGGCACCTCGAACATTGTTTTTGTCGTTAAGGATCCTAAAGTGCTGCGGGGACTG +ATCACATTTTTCTCAACAGTAAGTTAAGAATTTCAGTTACTGACATCCCTCAGTCCTGAT +TAAACCTATTTGATTTCACCAGTTTTTAACCCATCGTGTGTTTGGGTGTCTTCTCCCCAG +TCCCTGGCCCCACCTCTTCTGCCACAAACGTCAGCATGGTGGTATCTGCCGGCCCTTGGT +CCGGTGAGAAGGCAGAGATGAACATTCTAGAAATCAACAAGAAATCGCGCCCCCAGCTGG +CAGAGAACAAACAGCAGTTCAGAAACCTCAAACAGAAATGTCTTGTAACTCAAGTGGCCT +ACTTCCTGGCCAACCGGCAAAATAATTACGGTAAGTTCTATAGGCTCACCATCACAAAAG +CGATGAATGATGTCCTGTCTTCTCGCTGAGAAACTAAATGCTCTCTCCATCAAAAATAAG +TTCAACCCTCCCATACTTCTAGGAAAATAGAAATGGGCATTTTCACATTTTGTTAAATTG +GGAAGTCAGAGGTACCAAAGTATTTAGCAACTTTCCATGTTTGCAGTCAGGTGGGGGTGG +GCCTAGAGTTAAAATCGCAGTTATTCATTTGGGACACAGGCACAGAACGACCTGTTTTCT +CCAAGAGGCTAAATCGTGTTTTCAAGAATCCTCTCTGTACCATATAAGATCCGGCAGACA +AATAACATCTAGTCTGTTGTTCTAAATGTGTGGGACTAGTGAACCCTTATTGTGTTCAAG +CTTCTGTTGAGGCCCAATAGGCAAAGCTCTGTTCTGGGGACCCTGAGGAAAACTTGGTGA +TAGTACACAGTACCCGCTCTGAGGGGCTTCAAGGGGAGTCTGCTCCTAATAGAACCTGTG +GTATCTGTAAGTGACAGCATCAAGAGCAGGGAGTAGGGGCCGTGCACGGTGGCTCACTCC +TGTAATCCAAGCACTTTGGGAGGCTGAGGCGGGTAGAGCACGAGGTCAGGAGTTTGAGAC +CAGCCTGGGCAACGTGGAGAAACCCCATCTCTTCTAAAAATACAAACATTAGCTGGGCGT +GGTGGCGGGCGCCTGTAATCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATCCCTTGCAT +CCAGGAGGCAGAGGTTGCAGTGAGCCAAGAACACGCCATTGCACTCCAGCCTGGGCGATA +GGGCAAGACTCGTCAAAAGAAAAGCAGAGAGTACCCGGTGAGAGGGAAGTCCTGCTTCCT +GGGGCACAGGCTCTTGTTCCTAAAGAGGAAGAAGGATCGCACCCGAGATTGTGTGGAAGT +AGCAGTGCAGTGTGCAGACCAGGGACTCTGGGCCTGTCTCCTGGGCTCCATCCAAGTTGC +TTGTCTTGTCTGTCCCTCAGTTTCCTCATCTGTACATAGGGTACTACAGAAATACCTACC +TCTGTAAATTGCTGCAATGAGTTACATGAGCTGTTTCTTGTCAATCTCCTAGAACTTTTA +TTGGCACAGAGTTAACACTCTGTTAGTTCTTCATTCTACTGTTTCTAAATTAACACAAAC +CTTAGTATTCGGGCAGATTTCCTTCATGGCCTTATGGTCTTACGTCTCATCCTTTATGCT +TCAGATGTGATTCTTAAAATCACATCTAAAGCTATGATGTAAAAATCAAAGATGTTTAAG +ATCTTTGACATATTTGTCCTTGAACTTCCCAGTGAAAGGGAAACCATCAGTCCCATAGTC +CTAGGGGCCTTCCCAACTGTACAAGAAATCACTACTTCATGCCCCAGTGCAGTGCTTTAG +AGGAGAGGCTGCAAGGCTTGGGAAAGTGGCCCCGCATTCAGAGTCAGACCTCAGGGGCTG +TGAATTCTGACTCCACTTCATTGTGGTTGAATCATCTTGTCAACTTCCTTGATGTGCCTT +GAGTTTCTCTTCGTCTCTAAATTTTGGAGGATCAGCTGCCAGTAAGTCGGGAGACTGAAG +AGTAAAGATGTGGAAATCCCTACGTAGAGCCTGGCAGTGGGGACAGTTTTGTCCTTGGGA +TGGACCTGGCTCCTGCCCTGTAGGCAGTGACCAGAGCAGCATGTCCAGCCTTTCACTGAG +GCAGGCGTGTGTGTCTTTTCTCAGACTATGAAGACTGCAAAGACCTCATAAAATCTATGC +TGAGGGATGAGCGGCTGCTCACAGAAGAGAAGCTTGCAGAGGAGCTCGGGCAAGCTGAGG +AGCTCAGGTGAGTGGGCCCCCTGGGGTCAGGCAGGTGGGCAGGTGTGTAAATATCTGAAG +TACAGCAGCTCGGCAGGGAGAACTAAGAGCTGAACTGGGCCAGGGGAAGGGCAGGAATTG +CCATGGCAGGCTCACGACACACAAAGATTTATCAAGCAGAGAACAAGGATAATAATAAGT +TATGGGTTGCAGTTGTTTTTCAGAGCCTTATTTTCTGTTTTTCAAACAAGTAATTGTTGA +GGTGAAATGCGCATAACACAAAATTAACCGAAGGAGTGGGAACCACCGAGCAGCATTCGG +CATACTCAAAGTGATGTGCCATCACCACCCCACTCACCCTTAGTCAGAATCAGCTCCTGA +CTGACTGCGGCTTCTCATGCTTTCACTCAATGTTACCTTCTCGAGCCTGTCATTCCTTTC +TTTCATCTTTTCAATTGGCCCCATCTGCACCTGGCCTCATTTCTGTCCATGGCTTTGTAT +CTAGTCGCTGCAAGATGCACTATGTGTATATGCACGTGGAAATGTCCATGGCCAGAGTGA +GGAACTGAAAGGATGGATGTCTTTTTGAAACTGAATGAGGAAGACACCTACTTTTGTTGA +CAGAAGAGAAAGATGAATGGAACATCATGGAGGGTCTTCCAGGAGCCCTCTCTCATACAG +AGGAAGCCTGTGAACCATTTTTTATTCTTTCTCTTGGGCACAGACATTTCTTTAAACATG +TGCTGACCTTCTGCTTGGAGGTCTCCTTGAGGACATTGTCTCAGAAATCTGTGTTGCAAA +ATATTAGAACTGATCACTCATCCCTTTCCACTGTTAAATTTTCTCTACTATCTCACCTTA +GGCAATATAAAGTCCTGGTTCACTCTCAGGAACGAGAGCTGACCCAGTTAAGGGAGAAGT +TACAGGAAGGGAGAGATGCCTCCCGCTCATTGAATCAGCATCTCCAGGCCCTCCTCACTC +CGGATGAGCCGGACAACTCCCAGGGACGGGACCTCCGAGAACAGCTGGCTGAGGGATGTA +GGCTGGCACAGCACCTCGTCCAAAAGCTCAGCCCAGGTGAGGTGGCCATAGGCCCTGATG +ACCCAAAACCCCAGGCTTATGAGAGACTTCAGACCTCCATACTTTCACAATGACATTTGT +ATCGGTGGTGTTTTTTCCCACTAAACGTATGTGGCCGTGACATAAGTGACATAACCAGGA +CTTCCTGGGTAAGAACAGAGGTGGGAAACCGATTGGGTTGGAGGTCACAGTATTTCAAAT +GTCCCTCCTCCCTTGATGGAAGGTGGTCTTTGGAGCAAGAAGCTGCACGTTTCTAGTTTT +AAAGGACAGGAAGGAGGCTGTGACGGGAGGGCGCTTTTTAGAGTGAAAAGAGCTCTGGAC +TCAGAAGGCAGGTTCCCAGGCTGTCTCTTTGGCAATGTTCTTAGTAACTGTCGGTGAGTG +AGTGATTTATCCTTCCTGAGTTTCTCTGTCTCCATCTGCAAAGGCAGGCAAATTGTCTCT +TGCAAGAGTCTGAAGCATCCAAATGTGGGAACACTTAGGACTGCTTTTCAAAATGAGATA +AAGCCCCTCGCCATGTGGTGTTAGAGAAGGCACTTGATGTGGGGGCATTTGGTGGTAGGA +AGTGCTTGATACTGGAGCACTCTTCATGGAGAGAATGTCCCTGAATAACAGGGCAGAAGC +CACATGGAGGGCCTGTGCAGTCTCCTGATGCATAGAGGACTGTAGGGCAAGTTTGTCCTC +TCCTAAGAGAAAGAATTAGGTTTGAAATGTGAACTGTGACAGGACACCAAGCCCGTGCCT +GGGAATCAGACCTGTAGCCAGATGGGGGAGACAGCTGCCAAAGTTCAGAGAGAGGCTGTA +GGAGCCTCCATGATATGGGGAGCAAAAGGTCTTTTCAGTATTTGGCCACATCTTGATGGT +GGCCCTCCAGATCAGAAATGCATTGCCTGATGGATCGGGAAACCATGCCAGGGCATTTTG +TTAACGATAAAACATGAGAGCTTTCAGCTGAACAGTGACCATGCCTAGATGTTCATGTCT +GTGTGCACATTCGGCTGACTGTGCTTGCAGAGTGTGAATTGGGAAATATCTGAATGAACA +CTTCTGTATTTACAGAAAATGATGACGATGAGGATGAAGATGTTAAAGTTGAGGAGGCTG +AGAAAGTACAGGAATTATATGCCCCCAGGTAACGCTGAATAATCGGGAGCAAGTAATGGG +TGGTAACATATGAAAAAGGTCTAGGAGGCACACCCTCTCTGGCATCTATGATGGGCCGAA +AGCCTGCATTCCCTTGGCCACAGTATGAGAAACTCAAGCCAGCTTGGACACAGGGTGTGG +CAGCTGTTGTGTTTCTCTGTGTGTGGTGGGTGTCATGTCTGTACCGTACAGGGATAGCTG +AGTTTTCATCCTCCTCGGCTCCTATCTGTCCAGTGCAATGAACACCAGTTGCTGTCTTCC +TCTCTGGCTCCCATGGCTGCCATGCTCTGTTGCAGAGAGAAGAGGATTGCCTGTTCCCTC +TTAAAGGGATCCTCCTGTTTGCTTTCTTGGACCACTCTCTTAATGCCTCCTGTCGAAACC +AGCTAGCACTCCCTGGTGTCCAATCCCTCTGTGTTTAGTCTTCTGTCATCTCTATCCCAC +CTGGCTCATCAGGGAGGTGCAGAAGGCTGAAGAAAAGGAAGTCCCTGAGGACTCACTGGA +GGAGTGTGCCATCACTTGTTCAAATAGCCACCACCCTTGTGAGTCCAACCAGCCTTACGG +GAACACCAGAATCACATTTGAGGAAGACCAAGTCGACTCAACTCTCATTGACTCATCCTC +TCATGATGAATGGTTGGATGCTGTATGCATTATCCCAGGTAGCCTCTATTTTCCTGTGTC +TCACACCTTTTCCTATGCTGAGGAATATAAACTCTGAAGACAGGCTCTATACACACAGAT +TGGTTTTAATAAAATCTATTATGGTATTCTTAACAGAGATATCAAGGAGGTTTTCTGTCC +TTCTCAGCTCATGTCATGCCTTTGTCTCACAGTCCCCAGTGTCAAGTTACTGGACCCCAG +ACAAGTGTGACAATCTCATAGTCACCTGAGTGCAGGAGGTACACAGGAAGTATCTGTGAG +GCCTCGTACCTTTGATTCAGTATCTCTTGTCACCTGTGATTAAGTCGTCTGTCCCTGAAC +AATGTCCATGAAATTTCTCTGCCTTTTTAAGGCGACTGGCAGCCTTGCCTTTGTGTTTGG +AAATATTGTTCCCCAGGCTTCACTGCTCTCAGCTTTAATCTTGATCTCCTTTGAGTCTGC +TTGGTTAGCTGCACAGTCACCTTGAAATCAGGACAGAAACTTTTCTTTTTTACTTTGCTG +ATATAGTTCCATAAAGCAAGGCTGGACCCTGGTTCTCCACCCCATCAATGCAATGGCTGA +TGCAATGTTTTGTAGCATCATAGATTCTCTCTCTCTTTTTCTTTTCTTTTCTTTTTCTTT +TTCTTTTTTTTTTTGTGATGGAGTCTGGCTCTGTCACCCAGGCTGGAGTGCAATGGCTCC +ATTTTGGCTTGCTGCAACTTCCACCTCCCAGGTTCAAGTGATTCTCCTGCCTCAGCCTCC +TGAGTCGCTGGTACCACAGGTGCTCAGCACCACATCTGGCTAATTTTTGTATTTTTATTA +GAGACGGGGTTCCCCCATGTTGGCCAGGCTGGTCTTGAACTCATGACCTCAAATGATTCA +CCTTCCTTGACCTCCCAAATCACAGATTCTTTTTAATGCAAGAGTTGTTAGAATTTATCT +ATCAGTCGAGTTTCATGTGTAGATCCCTCTAAACATTTAATGTCCATGTTACCTGGTGAT +ATAAGTCAGTATTGCAACAACACTCCTAGAAAATTGTTTGACCAATTATTGGCGACTTTG +GGGGGAAAATTTTGTTTAACTTTGCATAGACTCAGGCAGGGAATATGGCATTATGGTCTA +CCCATAGAGGGAAATTTTGGCCTGTGGGTCTGGAAAGCAGGGTCATCTACTTCTCACCAG +AGTTAATCTAGGGCACCCTGGAGTGCTCCTGTCAGAATCCATATTCTTGCACTGAGAATA +GTTATGTCCTTGTCCTATGACTGGACACTGATTTGGTCATATGTGGAGTGTGAATTGCTT +AATGTGACCTGCTTCTCTGAATTTATTTCCAGAAAATGAAAGTGATCATGAGCAAGAGGA +AGAAAAAGGGCCAGTGTCTCCCAGGTAATGCCATGGAATTGTGGGCTGTTAATTCAATAG +TGGCAGCTGGAGTTTGTAGATTTAGAGAAAATGAGGAAGCAATGAATAGAACTTTTTATT +CCATTCACCCAGCTACAAGTTGTCCTTATTAACAATGTTGTACATTATTTGTGGCCCTTG +TGTTGGTTTTAATTTCGTAGTCCTCTCAAGATAGGAACTTGCAATCAGATGAGCCAGGTG +AACTAGCCAAACAGGGATTTCTTGTTGATCTTTTCAAAAAACCAGCTCCTGGATTCACTG +ATTTTTTTGAAGGGTTTTTTGTGTCTCTATCTCCTTCAGTTCTGCTCTGATCTTAGTTAT +TTCTTGCCTTCTGCTAGCTTTTGAATTTGTTTGCTCTTGCTTCTCTAGTTCTTTTAATTG +TGATGTTAAGGTGTTGATTTTAGATCTTTCCCTTCCTTGTGGGCATTTAGTGCTAGAAAT +TTCCCTCTCCACACTGCTTTAAATGTGTCCCAGAGATTCTGGTATGTTGTGTCTTTGTTC +TCATTGGTTTCAAAGAACATCTTAATTTCTGCCTTCATTTCGTTATTTACCCAGTAGTCA +TTCAGGAGCAGGTTGTTCAGTTTCCATGTAGTTGTGCAGTTTTGAGTGAGTTTCTTAATC +CTGAGCTCTAATTTGATAGCACTGTGGTCTGAGAGACAGTTTGTTGTGATTTCTGTTCTT +TTACATTTGCTGAGGAGTGCTTGCTGAGGAGTGCTTTACCTCCAACTATGTGGTCAATTT +TGGAATAAGTGTGATGTGATGCTGAGAAGAATGAATATTCTGTTGGTTTGGGGTGGAGAG +TTCGTAGATGTCTATTAGGTCTGCTTGGTGCAGAGCTGAGTTCAAGTCCTGGATATCCTT +GTGAACCTTCTGTCTCATTGATCTGTCAAATATTGACAGTGGGGTGTTAAAGTCCCCCAT +GATTATTGTGTGGGAGTCTAAGTCTCTTTTTAGGTCTCTCAGGACTTGCTTTATGAATCT +GGGTGCTCCCGTATTGGATATATGTACATTTAGGATAGTTAGCTTTTCATGTTGAATTGA +TCCCTTTGCAATTATGTAATGGCCTTCTTTGTCTCTTTTGATCTTTCTTGGTTTAAAGTC +TGTTTTATCAAAGACTAGGATTGCAACCCCTGCTTTTTTTTGCTCTCCATTTGCTTGGTA +GATCTTCCTCCATCCCTTTATTTTGAGCCTATGTGTGTCTCTGCACGTGAGATGGGTCTC +CTGCGTACAGCACACTGATGGGTCTTGACTCCTTATCCAATTTGCCAGTCTGTGTCTTTT +AATTGGGGCATTTAGCCTATTTACATTTCAGGTTACTATTGTTATGTGTGAATTTGATCC +TGTCATGATGATGTGAGCTGGTTATTTTGCCTGTTAGTTGATGCACTTTCTTCCTAGCAT +TGATGGTCTTTACAATTTGGCACGTTTTTGCAGTGGCTGGCTGGTACTGGTTGTTCCTTT +CCATGTTTAGTGCTTCCTTCAGGAGCTCTTGCAAGGCAGGCCTGGTGGTGACAAAACCTC +TCAGCATTTGCTTGTCTGTAAAGGATTTTATTTCTCCTTCACTTTTGAAGCTTAGTTTCG +CTGAGTATGAAATTCTGGGTTGAAAATTCTTTTGTTTATGAATGTCGAATATTGGCCTCC +ACTCTCTTCTGGCTTGTAGGGTTTCTGCAGAGAGATCCACTGTTAGTCTGGTGGGCTTCC +CTTAGTGGGTAACTCGACCATTCTCTCTGGCTGCCCTTAACATTTTTTCCTTCTTTCAAC +CTTGGTGAATCTGACAATTATGTGTCTTGGAGTTGCTCTTCTCGAGGAGTATCTTTGTGG +TGTTCTCTGTATTTCCTGAATTTGAATGTTGGCCTGCTTTGCTAGGTTGGGGAAGTTCTC +CTGGATAATATCCTGAAGAGTGTTTTCCAACTTGGTTCCATTCTCCCCGTCACTTTCAGG +TACACCAATCAAATGTAGATTTGGTCTTTTCACATAGTCCCATATTTATTGGAGGCTTTG +TTCATTTCTTTTTACTCTTTTTTCTCTAAACTGCTCTTCTCACTTCATTTCATTAATTTG +ATCTTCAATCACTAATACCCTTTCTTCCACTTGATCGAATCGGCTACTGAAGCTTGTGCA +TGTGTCACGTAGTTCTCGTGCCATGGTTTTCAGCTCCATCAGGTCATTTCAGGTCTCCTC +TACATTGTTTATTCTAGTTAGCCATTCGTCCAATCTTTGTTCAAGGTTTTTAGCTTCCTT +GTGATGGGTTTGCACATCCTCCTTTAGCTCGGAAAAGTTTATTACCGACTTCTGAAGCCT +ACTTCTGTCAGCTCATCAAAGTTATTCTCCGTCCTGCTTTGTTCCATTGCTGGTGAGGAG +CTCTGATCCTTTGGAGGAGAAGGGGCGCTCTGGTTTTTAGAATTTTCAGCTTTTCTGCTC +CAGTTTGTCCACATCTTCGTGGTTTTATCTACCTTTGGTCTTTGATGCTGGTGACCTACA +GATGGGGTTTTGGTGTGGATGTCCTTTTGTTGACGTTGATTCCTTTCTGTTTGTTAGTTT +TCCTTTTAACAGTGAGGTCCCTCAGCAGCAGGTCTGGTGGAGTTTGCTGGAGGTCCACTC +CAGACCTTCAAACAGGGATTTCTTGGTGTCACCTGTTCTCTCCCATGTGTTTAAATCCAG +GGAGAGAATGTATAAATGCTTTCTGCTTATTTTTTATTAGTGTGTTTGCTAGTATTTGTG +TAAGCAAAGAAATTGAAAAAATAAACATATTATATCAAAATATTGTAAAAAGGGGACCCT +TAATACACAAGATCTGTGTCTGCACTGCCTCAAGAGCTCTGTTCACTTGAATGCTGCATG +TAAAATTCATCCCAATTTAGACGAAGTAGTTGAAGCCCTGTGTTAGTTCTCTGTGCTGCA +AGTCATGATGGTAGTTTACAGAGAGAGTCTGGGTGCCCTGCATTGGCTGATCTGTGGCAA +ATGTACTGAGCACGTGCTGCCCATTTTTGTTCGGTCCTCAGAGCAGTCACCCTCCAGCCT +GCATTTAGAAGGATAGTTTTATTTCTCTTGAAGGAAAAATGCCTTTGGTTTCTGTGAGCA +CTCCATTCTGTCTCCCATCAGATCATCTGGAAGGTTTTGTTGTCTAATCTCTGTTGGTTA +TATCTTCTGTCATCCCTGTCCTGCCTGGCTCATCAGGAATCTGCAGGAGTCTGAAGAGGA +GGAAGCCCCCCAGGAGTCCTGGGATGAAGGTGATTGGACTCTCTCAATTCCTCCTGACAT +GTCTGCCTCATACCAGTCTGACAGGAGCACCTTTCACTCAGTAGAGGAACAGCAAGTCGG +CTTGGCTCTTGACATAGGCAGTGAGTACTCCATTTTGAAGGTGATAAAGCTCCAGTTCAT +GTCCCAGGTAGACCCCATAATCTTTGGGCCTTGTGACCCTGGTTGGGCTGAGAGTTGCCA +TCACTGTGGGTGGAACCTATATATCAATGTAGATTTCAATCACTCTGGAATCGAGTCTGA +AGCACAGGCGTGGGGTGGGTCAGTGAGCTTTGCTCTCTTCCTAGTCTCAGGCCATGCCTG +TGCCACCCTGGACTGACTGTCAGGACACTGAACACAAGACGGGCGTGGCAAACTCACACC +AAGCTGTGCAGCATATGTCCAGGAGTTGTCTGTCAGATCAGCTCACCTGAGTTAAACGTC +TCTTGCCAGCTACAAAGTTCTTTATGAGTTTTGTTCCCAAAGCATGTCTGTGCAGTGCTT +TACCTGCCCAAGGCCAGTGTCACCCTTGTCTACCTCTCCGTGGAAGATGTGACCCAGGTT +TCACTGAATTTTTCCCCCTTTTCTGTGTCTTCTAAGTTGGCTTGTCATAGCTCATCTGTC +CATCATCTTGCTGGTATGTTTTCTAGATAAATGGCTGACTTTTCACCCACAAAAGCCATG +ATAGCTGATGCTTCTGTGTAGAACCAAGTGTCACTTTGACTCAAGAGCTGGTACATTGCA +CCCCTCCATCAAATCTCAGTGTCCACAATCTCATAAACTATCAAATCTGGGTATTTGAAG +AGAGAAGCCTGAATATTGCAGTATCTCTCCTATGAGGCATTAGAATGATTTGCCTCAAAT +CTATTGGGAAAAACATTGCTCATTTGTGTACACAAACCTAGGACAGAGCACACTGGGAAG +ATCACATTCCAAAACAGGGGCATTTTGCCCAAGGCTCATGAAAGGAACCAAGTCAGTTCT +CTCAAGACTTGCCCTCAGGCCTCCTGGTATATTTCTCTCAAAGTCTCCTATTCTCACACT +GAGAAGACTGATGTCCCTGTGTTAGGATTGGACAGAGGAATGTTTCCGTGTGCAAGGAAG +AACTGCTTCATGTAAGAGGCCCTGTCTGAATTTATTTGCAGGACATTGGTGTGATCAAGT +GAAAAAGGAGGACCAAGAGGCCACAAGTCCCAGGTGAGTCTGAGAAATTATGGACAGTTA +ATTTGATGTTGACACCTGGAGATGCCAAGTCCGGGGAAAGCAGTACATGCTGAAAATGAT +GATTTCATCTTGTCAGACAAGTCTGAATTATGTCTACTAACATTGCTTTTGGTTCTCATT +ACAGTAAATGTTTAGGTTTCCATTTCTTCCTATCCTTCTCATTTACTAACCTAGTGAAGG +TTGACCATACTTCAAAAGCTGTATTCTCATGGTGACTGCAGGGAAGCTTGAGCACATTTT +ATGCAAAATTGTTGAGCCCACTCTTTTCATGATCACTGTTCATTGTGTGTCCTGAAGGCA +CAAATATAGAGTGTTCTTTGACTCTCTCATCAGTGTGTCACCTGGCCAATTCACTGAGCT +CACTATCTCTCTCTCTCTCTCTCTCTCTCTCTCTGTGTGTGTGTGTGTGTGTGTGTGTGT +GTGTGTATGTGTATGTCTTTCTCTTTCATCCTTTTCTACCTGGCCCTGGTCTGTCCCAAC +ATGAAGGCAATAATTTGTTACCTCATTAATAGATCTGTCCTTTTTCTTTTCAAACAGTTC +CTTATGTTACCCATGAAATCTAGCTGGGGCTGTGTGGTTTCTGATTCCCCCTGGCTTATT +CTTTACTTTTCCTACTTTTCCAGGCTCAGCAGGGAGCTGCTGGATGAGAAAGAGCCTGAA +GTCTTGCAGGACTCACTGGATAGATTTTATTCAACTCCTTTTGAGTACCTGGAACTGCCT +GACTTATGCCAGCCCTACAGAAGTGACTTTTACTCATTGCAGGAACAACACCTTGGCTTG +GCTCTTGACTTGGACAGTGAGTACCTTACTATGAAGGTGATAAGACTCCACCTGGTCCTC +CAGATATGGGTGATATTCCTGTTCCAAGTGGCCCTTATTGACCCGAGAGATGTCATTGCC +ACAGGCAGGACCCGTGGGCGCATAGAGGTTGTAATGAAATTGTAGTTTCAGTTGGAAGCC +CAGACATGAAATGGGTCAGTGAGCATGGCTCTATTCCTAGTCTCCAGCCATGCCTGTGGC +AACCTGAGCCCACTCTCAGCACATTGGACCCAGGCAGGTGTAAAAAATTCACAGAACCAT +GATTTGGACTCAAGGGTTTGTAGATTTCCTCCTTCATTCAAATTTCAGTGTCTTGCAACC +ACGAATGAGCTGGGCATTTGATGAGACAGGGCTGAATACTGCAGTTTTCCTCCTAGAAAT +CATCTGGGGCATTTTCTTTGAATTGATGGGAGCAATAAGGCATAACTGTTTGCACAAACT +TGGGATAAATGATTTTGGGATAACTGTCTACCAGAATAGGGACATTTCACCCTTGGTTCT +GAGATGCAAACCAAAGAATCTCTATCATGACCAGCTTTGAGGCCTCCTGAAGTATATCTC +TCACATTGTCCTGTTCTCATGCTGAGGAGCCTGAGGTCCCTGTGTGGGGATTAGACAGTG +GACTGTTAATGGGTGTAGGTGAATTGGCTTATCTTGTCTGTCCCTGTCTGAATTTATTGC +AGGAATGAAAAAGGACCAAGAAGAGGAAGAAGACCAAGGCCCACCATGCCCCAGGTAAGT +TTGAGCAATTGTCAACAGCTAATTCTGTGTTGACACCTGGAGACTCCTGGTTCAGGGAAA +GCAGAGCAGGCCGACATTATCGATTACATGTTTTCAACCAAGCCTGAATTATTCCTACTC +ACATTGCTATTGGTTTTCATTGCAGTAGATATTTAGGTTTCCGTTTCTTCCTCCCCTTAT +CACTTACTAACCTACTGTAGGTCGACCATACTTCAAAAGCTGTATCCTCATGGTGACTGC +ATGGAAACTTGAGCACATTTTATGGAAAATTATTGAGCACAGTCTTTTCATGATCACTGT +ATGCTGTGTGCCCTGAGGGCACTAACTCAGAGTGTCCTGTACTCCCTCCTCAGTGTGTCA +CCTGGACAATTCAGTGAGCGCTCACTCTCTCTCTCTCTGCCTCTGTCTCTCTGTCTCTCT +GTCTTTCTCTTTCATTCTTTTCTGTTTGGCCCTGTGCCATCCCAACTGAGGGCAATAATT +TGTTACCTCATTAATGGATGTATCCTTTTTCTTTTTTAACCACTTCCTAATGCTACCCAT +GAAATCTAGTTGGGGCTCTGTGGTGTCTGATTTCCCCTGGCTTATTCTTTACTTTTTCTA +CTTTTCCAGGCTCAGCAGAGAGCTGCCGGAGGTAGTAGAGCCTGAGGACTTGCAGGACTC +ACTGGATAGATGGTATTCGACTCCTTTCAGTTATCCAGAACTGCCTGATTCATGCCAGCC +CTACGGAAGTTGCTTTTACTCATTGGAGGAAGAACACGTTGGCTTTTCTCTTGACGTGGA +TGGTGAGTACCTTTCTATGAGGGTGATAAGGATCCACTGAGTTTTCCGTATAGAGATCCT +ATTCCTGCTCTAAGAGGCCGTTACTGAGCTGAGAGATGTCATTGCTGCACTGAGGACCTA +TAGGCACATATAGGTTGAACGAAACTCTAGTTCTACCTGGAAGCCCAAACATGGGATGGG +TCAGTGAGCGTGGCTCTCTTCCTAGTCTCAGGCCATGCCTGTGGCACTCTGATTCTACTC +TCAAGGCATTGGACCTGGGCAGATGGGACAAATTCAGAGAACTATGATTTTGACTCAAGG +GTTTGTAGATTTCCTTTCTCACTCTAATTTCAGTGTCTAAAATCCTCACAACTATGAACA +ATCTGAGTATTTGATGAGACAGGGCTGAATATTGCAGTTTTTCTCCTAGAAATCGTTTGA +GGGCATTTGCTTTAAATTGATTGGAAAGATATGGCATAACCGTTTGCACAAACTTGGGAC +AAATGATATTGGGATAATGATCTACCAGAATAGGGACATTTTACCCTTAGTTTCTGGGAC +AAAAACCAAGGAATCTCTATCATGACCATCCTTCAGGCCTCCTGAAATATATCTCTCACA +GTGTCCTATTCTTATGCTGAGGAGCCTGAGGTCCCTGTGTGAGGATTAGACAGTGGAATG +TTATGTGTGTAGGGGAATCAGCTTAATGTGTCTGTCCATGTCTGAATTTATTGCAGAAAT +TGAAAAGTACCAAGAAGGGGAAGAAGATCAAAAGCCACCATGCCCCAGGTAACTTTCAGC +AATTGTGGTCGCTTAATTCTGTGTTAACACCTGGAGACAACAGATCCAGGGAAAACAGTG +TGTTTGATTTCATGTTTTCAATGAAGGCTGAATTACTCCTGCTGACATTGCTATTGGTTT +TCATTGCAGTAGACGTTTAGGTTTTCATTTCTTCCTCCCCTTATCATTTACTAATGTACC +ATAGGTTGACCATACCTCAGAAGTTGTACCCTTATGGCGACTGCATGGAATTTTAAGCAC +ACTTGATGGAAAACTATTGAGCTCACTCTTCTCATGATCACTGTTTGCTGTGTGTCCTGA +GGGCACTAACTCACAGTGTCCTTTTACTCCCTCATCAATGTGTCACCTGGCCAATTCACT +GAGCTCACTTTCTCTCTCTCTCTGTCTCTCTCTCTCACTCTCTGTCTTTCTCTTTCATTG +TTTTCTACTTGGCCCTGTTCTATCCCAACATAAAGGCAATAATTTTTTTACCTCATTAAT +GGAACTATCCTTTTCCTTTTTTGACCACTTCCTTATGTTACCCCTGAAATCTAGTTGGGG +CTCTGTGGTGTCTGATTTTCCCTGGCTGCTTCTTTAGTTTTGTCTCCTTTTCCAGGCTCA +ACGAGGTGCTGATGGAAGCAGAAGAGCCTGAAGTCTTGCAGGACTCACTGGATAGATGTT +ATTCGACTACTTCAACTTACTTTCAACTACATGCCTCATTCCAGCAGTATAGAAGTGCCT +TTTACTCATTTGAGGAACAGGACGTCAGCTTGGCCCTTGACGTGGACAATAGGTTTTTTA +CTTTGACAGTGATAAGGCACCACCTGGCCTTCCAGATGGGAGTCATATTCCCACACTAAG +CAGCCCTTACTAAGCTGAGAGATGTCATTGCTGCAGGCAGGACGTATAGGCACATGTAGG +TTTGAATGAAACTGTAGTTCCCTTTGGAAGCCCAGTCATAGGATGGGAAAGTGGGCATGG +CTCTATTCCTATTCTCAGACCATGCCAGTGGCCACCTGTGCTCAGTCTGAAGACGTTGGA +CCCAAGTTAGGTGTGACACGTTCACACGACTATGTAGCACATGCCGGGAGTGATCTGCCA +GACATTCTAATTTGAACCAGATATCTCTGGGTAGCTACAAAGTTCCTCAGGGGTTTCATT +TTGCAGGCATGTCTCTGAGCTTCTATACCTGCTCAAGGTCAGTGTCATCTTTGTGTTTAG +CTCATCCAAAGGTGTTACCCTGGTTTCATTGAACCTAACCCCATTCTTTGTATCTTCAGT +GTTGGTTTGTTTTAGCTGATCCATCTGTAACACAGGAGGGATCCTTGGCTGAGGATTGTA +TTTCAGAACCACTGACTGCTCTTGACAGTTGTTAACCCACTAGGCTCCTTTGAGTAGAGA +AGCCATAGTCCTTCAGCCTCCAATTGATATCAATACTTAGGAAGACCACAGCTAGACGGA +CAAACAGCATTGGGAGGCCTTAGTCCTGCTCCTTTCAATTCCATCCTGTAAAGAACAGGA +GTCAGGAGCCGCTGGCAAGAGACAGCATGTCACCTGGGACTCTGCCAGTGCAGAATATGA +ACAATGCCATGTTCTTGCAGAAAATGCTTAGCCTGAGTTTCATAGGAGGTAATCACCAGA +CAACTGCAGAATGTAGAACACTGAGCAGGACAACTGACCTGTCTCCTTCACACAGTCCAC +GTCACCACGAATCACACAACAAAAAGGAGGAGAGATATTTTGGGTTCAGAAGAAGTAAAT +GATAATGTAGCTACATTTCTTTAGTTATTTTGAACCCCAAATATTTCCTCATCTTTTTGT +TGTTGTCATTGATTTTGGTGACATGGACTTGTTTGTAGAGGACAGGTCAGCTGTCTGGCT +CAATGGTCTACATTCTGAAGTTGTCTGAAAATGTCTTCATGATTAAATTCAGCCTAAACG +TTTCATCAAGAACACTACAGAGTCGATACTGTGAGTTTCCAACCTCAGCCCATCTGTGGG +CAGAGAAGGTCTAGTTTGTCCATCAGCATTATCATGATATCAGGACTGGTTACTTGGTTA +AGGAGGGGTCTAGGAGATCTGTCCCTTTTAGAGACACCTTACTTATGATGAAGTATTTGG +GAGAGTGGTTTTTCAAAGTAGAAATGTCCTGTATTCCAGTGATCATCCTCTAAACGTTTT +ATCATTTATTAATCATCCCTGCCTGTGTCTATTATTATATTCATATCTCTACGCTGGAAA +TTTGCTGCCTCAATGTTTACTGTGCCTTTGTTTTTGCTAGTGTGTGTTGTTGAAAAAAAA +ACATTCTCTGCCTGAGTTTTAATTTTTGTCCAAAGTTATTTTAATCTATACAATTAAAAA +CTTTTGCCTATCACTCTGGACTGTTGGATTGTTTTTTACATTCAGCGTTATAATCTTTTG +TTATGCTGATTGGTTTTGGTGGGTACTGATGCGAATTAATAAAAACATTTTCATTTCC diff --git a/test/csq/ENST00000318249/ENST00000318249.fa.fai b/test/csq/ENST00000318249/ENST00000318249.fa.fai new file mode 100644 index 0000000..637e699 --- /dev/null +++ b/test/csq/ENST00000318249/ENST00000318249.fa.fai @@ -0,0 +1 @@ +1 44878 23 60 61 diff --git a/test/csq/ENST00000318249/ENST00000318249.gff b/test/csq/ENST00000318249/ENST00000318249.gff new file mode 100644 index 0000000..18787c8 --- /dev/null +++ b/test/csq/ENST00000318249/ENST00000318249.gff @@ -0,0 +1,34 @@ +1 ensembl_havana gene 1 44878 . + . ID=gene:ENSG00000142794;Name=NBPF3;biotype=protein_coding;description=neuroblastoma breakpoint family%2C member 3 [Source:HGNC Symbol%3BAcc:25076];gene_id=ENSG00000142794;logic_name=ensembl_havana_gene;version=14 +1 ensembl_havana transcript 11 44772 . + . ID=transcript:ENST00000318249;Parent=gene:ENSG00000142794;Name=NBPF3-201;biotype=protein_coding;ccdsid=CCDS216.1;tag=basic;transcript_id=ENST00000318249;version=5 +1 ensembl exon 11 221 . + . Parent=transcript:ENST00000318249;Name=ENSE00001542593;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001542593;rank=1;version=1 +1 ensembl five_prime_UTR 11 221 . + . Parent=transcript:ENST00000318249 +1 ensembl five_prime_UTR 4821 4959 . + . Parent=transcript:ENST00000318249 +1 ensembl exon 4821 5092 . + . Parent=transcript:ENST00000318249;Name=ENSE00003631247;constitutive=0;ensembl_end_phase=1;ensembl_phase=-1;exon_id=ENSE00003631247;rank=2;version=1 +1 ensembl CDS 4960 5092 . + 0 ID=CDS:ENSP00000316782;Parent=transcript:ENST00000318249;protein_id=ENSP00000316782 +1 ensembl exon 28561 28770 . + . Parent=transcript:ENST00000318249;Name=ENSE00003487448;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00003487448;rank=3;version=1 +1 ensembl CDS 28561 28770 . + 2 ID=CDS:ENSP00000316782;Parent=transcript:ENST00000318249;protein_id=ENSP00000316782 +1 ensembl exon 30505 30607 . + . Parent=transcript:ENST00000318249;Name=ENSE00001724864;constitutive=0;ensembl_end_phase=2;ensembl_phase=1;exon_id=ENSE00001724864;rank=4;version=1 +1 ensembl CDS 30505 30607 . + 2 ID=CDS:ENSP00000316782;Parent=transcript:ENST00000318249;protein_id=ENSP00000316782 +1 ensembl exon 31442 31656 . + . Parent=transcript:ENST00000318249;Name=ENSE00001617203;constitutive=0;ensembl_end_phase=1;ensembl_phase=2;exon_id=ENSE00001617203;rank=5;version=1 +1 ensembl CDS 31442 31656 . + 1 ID=CDS:ENSP00000316782;Parent=transcript:ENST00000318249;protein_id=ENSP00000316782 +1 ensembl exon 32716 32788 . + . Parent=transcript:ENST00000318249;Name=ENSE00001618625;constitutive=0;ensembl_end_phase=2;ensembl_phase=1;exon_id=ENSE00001618625;rank=6;version=1 +1 ensembl CDS 32716 32788 . + 2 ID=CDS:ENSP00000316782;Parent=transcript:ENST00000318249;protein_id=ENSP00000316782 +1 ensembl exon 33253 33458 . + . Parent=transcript:ENST00000318249;Name=ENSE00001316812;constitutive=0;ensembl_end_phase=1;ensembl_phase=2;exon_id=ENSE00001316812;rank=7;version=2 +1 ensembl CDS 33253 33458 . + 1 ID=CDS:ENSP00000316782;Parent=transcript:ENST00000318249;protein_id=ENSP00000316782 +1 ensembl exon 34773 34824 . + . Parent=transcript:ENST00000318249;Name=ENSE00003569827;constitutive=0;ensembl_end_phase=2;ensembl_phase=1;exon_id=ENSE00003569827;rank=8;version=1 +1 ensembl CDS 34773 34824 . + 2 ID=CDS:ENSP00000316782;Parent=transcript:ENST00000318249;protein_id=ENSP00000316782 +1 ensembl exon 38017 38180 . + . Parent=transcript:ENST00000318249;Name=ENSE00001619353;constitutive=0;ensembl_end_phase=1;ensembl_phase=2;exon_id=ENSE00001619353;rank=9;version=1 +1 ensembl CDS 38017 38180 . + 1 ID=CDS:ENSP00000316782;Parent=transcript:ENST00000318249;protein_id=ENSP00000316782 +1 ensembl exon 39222 39273 . + . Parent=transcript:ENST00000318249;Name=ENSE00003497364;constitutive=0;ensembl_end_phase=2;ensembl_phase=1;exon_id=ENSE00003497364;rank=10;version=1 +1 ensembl CDS 39222 39273 . + 2 ID=CDS:ENSP00000316782;Parent=transcript:ENST00000318249;protein_id=ENSP00000316782 +1 ensembl exon 39924 40096 . + . Parent=transcript:ENST00000318249;Name=ENSE00003594154;constitutive=0;ensembl_end_phase=1;ensembl_phase=2;exon_id=ENSE00003594154;rank=11;version=1 +1 ensembl CDS 39924 40096 . + 1 ID=CDS:ENSP00000316782;Parent=transcript:ENST00000318249;protein_id=ENSP00000316782 +1 ensembl exon 40803 40854 . + . Parent=transcript:ENST00000318249;Name=ENSE00003524606;constitutive=0;ensembl_end_phase=2;ensembl_phase=1;exon_id=ENSE00003524606;rank=12;version=1 +1 ensembl CDS 40803 40854 . + 2 ID=CDS:ENSP00000316782;Parent=transcript:ENST00000318249;protein_id=ENSP00000316782 +1 ensembl exon 41470 41642 . + . Parent=transcript:ENST00000318249;Name=ENSE00003655848;constitutive=0;ensembl_end_phase=1;ensembl_phase=2;exon_id=ENSE00003655848;rank=13;version=1 +1 ensembl CDS 41470 41642 . + 1 ID=CDS:ENSP00000316782;Parent=transcript:ENST00000318249;protein_id=ENSP00000316782 +1 ensembl exon 42357 42408 . + . Parent=transcript:ENST00000318249;Name=ENSE00003531648;constitutive=0;ensembl_end_phase=2;ensembl_phase=1;exon_id=ENSE00003531648;rank=14;version=1 +1 ensembl CDS 42357 42408 . + 2 ID=CDS:ENSP00000316782;Parent=transcript:ENST00000318249;protein_id=ENSP00000316782 +1 ensembl CDS 43016 43259 . + 1 ID=CDS:ENSP00000316782;Parent=transcript:ENST00000318249;protein_id=ENSP00000316782 +1 ensembl exon 43016 44772 . + . Parent=transcript:ENST00000318249;Name=ENSE00001277853;constitutive=0;ensembl_end_phase=-1;ensembl_phase=2;exon_id=ENSE00001277853;rank=15;version=3 +1 ensembl three_prime_UTR 43260 44772 . + . Parent=transcript:ENST00000318249 diff --git a/test/csq/ENST00000318249/ascii-art.txt b/test/csq/ENST00000318249/ascii-art.txt new file mode 100644 index 0000000..dbaa333 --- /dev/null +++ b/test/csq/ENST00000318249/ascii-art.txt @@ -0,0 +1,9 @@ + +4959 GA G + 4960 + xxxxxxxxx +CACACTGGGGATGCCACTGAC + G- + + + diff --git a/test/csq/ENST00000318249/start-lost.txt b/test/csq/ENST00000318249/start-lost.txt new file mode 100644 index 0000000..dfbef24 --- /dev/null +++ b/test/csq/ENST00000318249/start-lost.txt @@ -0,0 +1,3 @@ +4959 GA G frameshift&start_lost|NBPF3|ENST00000318249|protein_coding|+|1M>1?|4959GA>G +4959 GA G frameshift&start_lost|NBPF3|ENST00000318249|protein_coding|+|1M>1?|4959GA>G + diff --git a/test/csq/ENST00000318249/start-lost.txt-l b/test/csq/ENST00000318249/start-lost.txt-l new file mode 100644 index 0000000..dfbef24 --- /dev/null +++ b/test/csq/ENST00000318249/start-lost.txt-l @@ -0,0 +1,3 @@ +4959 GA G frameshift&start_lost|NBPF3|ENST00000318249|protein_coding|+|1M>1?|4959GA>G +4959 GA G frameshift&start_lost|NBPF3|ENST00000318249|protein_coding|+|1M>1?|4959GA>G + diff --git a/test/csq/ENST00000318249/start-lost.vcf b/test/csq/ENST00000318249/start-lost.vcf new file mode 100644 index 0000000..a9db115 --- /dev/null +++ b/test/csq/ENST00000318249/start-lost.vcf @@ -0,0 +1,6 @@ +##fileformat=VCFv4.2 +##contig= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO +1 4959 . GA G . . EXP=frameshift&start_lost|NBPF3|ENST00000318249|protein_coding|+|1M>1?|4959GA>G;type=ENST00000318249:21771579-GA-G diff --git a/test/csq/ENST00000318249/start-lost.vcf.ori b/test/csq/ENST00000318249/start-lost.vcf.ori new file mode 100644 index 0000000..f4a827b --- /dev/null +++ b/test/csq/ENST00000318249/start-lost.vcf.ori @@ -0,0 +1,5 @@ +##fileformat=VCFv4.2 +##contig= +##INFO=1 1:16330731-16335302 +ACATCCTGGAAGAGTGGCCTAGGACAGCTCCTCTCCTGCCAGAGCTAGGCAGGCGCCGAA +GTAGCCGCATGGCCCCGTCAGAAGACCCCAGGGACTGGAGAGCCAACCTCAAAGGCACCA +TCCGTGAGACAGGCCTGGAGACCAGCTCCGGTAAGAGGCGGCAAAGGGACCCCAGCCCCA +CAGAAACACCAGCTGGGGGCCAGGTGCGGTGCCTCATGCCTGTAATCCCAGCACTTTGGG +AGGCCGAAGCGGGCAGATCATGAGGTCAGGAGTTCGAGACCAGCTTGGCCAACATAGTGA +AACCCCATATCTGCTAAAAATACAAAAAATTAGCTGGGTGTGGTGGCGGGTGCCTATAAT +CCCAGCTACTCAGGAGGTTGAGGCAGGAGAATCGCTTGAACCCAGGAGGCGGAGGTTGCA +GTGAGCTGAGATCGCACCACTGCACTCCAGCCTGAGCAACAGTGTGAGACTCCATCTCAA +AAAAAAAAAAAAAAAAAAAAAAGCAAGACCAGCTGGGGGTGGGTGGGGGTCTGATGGCAA +ACATGCTACCTCCCTTGGGTTGCTGGGATTCTCCAGCCAAGGGCGGGCTCGTTTTATTTC +CTGTGCTAGCCAACCTACTAGAACATAAGCTTCCTTCTGAGCCCACGTCGTGTTTCACAG +CACGTAGCTAAGAGAATGGATGTGTATGTTATTTGGGTAACTCAAAAAGTTACCTTTTTA +AGAGCACAGGCTTTGGATTCAGATACAATTGCTCAGACACCTGCTTCATTGATAAGTCTA +TTGGCTGGTTTGTCCATCCCTCTACCCTGTGCTGGGCTCTGAGCGGGGGGATTGCCAGGG +CAAATGCCACCAGGTACTGATGGGATTCTCTGAGGCTGTGGACAAGATTATCTGGGGAGG +GGGAGAGTAGCAAGATGCTCCCTGAGACCCACCAACACTTGTGCAGGCTGAGCCTCAGTT +TCCTCACCTGGAAAGATGGCCAGGGCTTTCCTCTCTGGGGTTGAGGACTGTGCTTTTCAT +AATATGGTCCATGGACCAGCAGAATTGGCATCCCCTGGGGACTTGTTAGAAACGCGAGTC +TCAGGCCCCACCCCAGCCCCACTGCACCAGACTCTGCATTTTAACAAGCTCCCCAGGCAG +CTCATGGGAACAGCAAAGTTGGGAGGCACTGACATGTTGGACTCTGTGTTCCTGGAAGGC +AGATGGATGGATGGTAAGTGGAGACTTGAACTCAGGTCTCTCTGATGCTGAAGTCCATAC +ACTTAAACCCTGACTGTCCTCCTCTGTTGGTGTATCAACCAATCCAGTTGAACCCTATCG +AATGAATAAACAAATGAATTCAGGAAACCATGTCCCAGTCGGGTGCAGTGGCTCACGCCT +GCAATTCCAGTACTGATTGGGCTGAGGCAGAAGGATTTCTTGAGTCCAGGAGTTTGAGAC +CAGCCTGGGCAACATAGGGAAACCTCATCTCTACAAAAAATTTTAAAATTCACCAGGCAT +GGTGGCATGAGCCTGTAGTCCCAGCTACTTAGGGGGCTGAGATGGGAGGATTGGTTGAGC +CCCCTGAGGCTGAGGCTGCAGTGAGCCATGACCTCCAGCCTGGGCGACAGAGTGAGACCC +TGTCTCAGGGGAAAAGAAAAGTCCCCTGCTTGTGCTAACTTTTGGTCTTTTCCTCTCTTC +TAGGTGGGAAGCTGGCTGGCCATCAGAAGACCGTCCCCACGGCTCACCTGACTTTTGTTA +TTGACTGCACCCACGGGAAGCAGCTCTCCCTGGCAGCAACCGCATCACCACCCCAAGCCC +CCAGTCCCAATCGAGGGCTTGTCACCCCACCAATGAAGACCTACATCGTGTTCTGTGGGG +AAAACTGGCCCCATCTGACTCGGGTGACCCCCATGGGTGGGGGATGCCTTGCCCAGGCCA +GGGCCACCCTGCCGCTCTGCAGAGGGTCTGTGGCCTCAGCTTCCTTCCCAGTCAGCCCGC +TCTGCCCCCAGGAGGTTCCCGAGGCTAAGGGGAAACCCGTGAAGGCTGCGCCTGTGAGGT +CTTCAACTTGGGGAACAGTCAAGGACTCACTGAAAGCCCTCTCCTCTTGTGTCTGTGGGC +AGGCCGATTAGCTGGAAGGGCCGGGCTCTGATGCCCAGAGGCTGCAATTCCCAGGGCCTG +GCCCTGCTTCCCCAGCTAAGCAGGAGTCTTTTGTGCTTGAGCCAAGGAAACATCATTAGA +TCCGCTAAGGGGCATCTGAAACATCCGTCGAGTGGCAGAGGCAGGATAAGTCACCTGCAC +ATGAAGAGACTCATTCATTCATACAGCAAATATTACTGGTACATCTTCCACATGCCAGGC +CCTGCAAAGTGCTGGGGAGATACCATGGTTTTCCTGGAGCTGGTATTTTTGGGGTGGAGG +GAACCCACCCTGAATAAATAAAGTAACCCAATAAATAAAGAAGATGATTTTGAACAGCGA +TGAATGCTCTGCAGGAACTGAAACAGGATGCTAGAGGGAGAGTGATTGGGGTGAAGACCT +TTCCTGATGCAGTGCTTGGTAAGGGCCTCTCTGCGCAGGCAACAAAGTGTGATCTAAAAG +ATGAGAAGGGGCCAGCCCTGAGAAAATCCACCCTCCCCAGGGCCACCTGCTGTCATCTTA +CCCCAGGGCAGGCCAGAGCAGTGGTCAGAATGCCCCAGCATGACGGGGAGGGGCAACGGG +TTTCTTGCTGCCATCTTGGCTCAGAGGCGAGTGTGTAGGTCACTGCAAAGGCAGGGGATA +CCACGTGGGGAGACTCGAGGGCCATGCCAGTTGGGGCTGGGAGGCTCAGGGAAGTTGGCT +CCAGGAGACTCCATCCCATAAGGCAGCCCAGGTGGGACCTGGGGATCTGAGATGGGAAAT +AAGGGGATCTGGCTTCTCAAAAGGGAGGGAGGTACTCAAAAATAGAGTATCATGTTTGAA +CGAATGAAAACAAGACATGTTATTTATTGAGCATCTACTGCATACCAGGCTCATGCTGCC +CTCTAGGGATAGCAAAAAAAAAAAAAAAAGGTGGGGGGAGGAGGTTCACCCCTCAGGGCA +ATCGTGTTCCCTGAGCAGGAGGTGGAGTTACTGGTGTGGGTGTGAAGGTGTCTGTGAGTC +TAAGGCATGCACAGCACTGTGAGAAACCCTAAAGCAACCTATTTAAGGAAGTCAGTCTCA +AAGCTCCCAGATAAAAATCACTGGGTTTTTCTGTATTTATTTTAGAGACAGAGTCTCACT +CTATCACCCAGGCTGGAGTGCAGTGGAACAATCACAGCTCACTGCAGCCTCAAACTCCTG +GGCTCAAGTGATCCTCCTGCCTCAGCCTCCCGAGTAGCTGAGACTATAGGTGCACCACTA +CGCCCAGCTTGACTTCTTTTAGTAGAGAAGAGGTCTCACTGTGCTGCCCAGGCTGGTCTT +GAACTCCTGGCCTCAAGCTATCCTCCCGCTTCAGCTTCCCTAAGTGCTTGGATTATAGGT +GTGAGCCACCGTATCTGGTCATTAATTTATTCAATGACTATTTTACTAGGTTCCTACAAA +TACTAGCTGCTAACATTTAACATGTAATTGACCATTTACTCTGTGTCAGAGAAACAACAT +GGGCACTGTATTTGTGACCATTTTATAGATTAGAGAGCTGAGGCACAGAGAGGTTGAAGA +ATGGACTCAAAGTTCCATAGACTGGTACCATTGAGATTAGAACTCAGGCAAGTCTGGTGC +CCATATTCTTGCTTGTAACTGTAAGGTATATACCCTCTCATCCTGGTAGCGTCTCTTCTA +GGCAGAGGGGACACACAGAGGATAAATGTAACCCTGTCCTCAAGGAGCTCACAGCCAGGT +GGGGGAGGCCAGAAAGAAAGCACACAATTGCCATAGCTTCTGAGAAGTGCAACAGTAAGG +GCAACACAGAATGATGCTGGAGGACAACCAGCCCACTCTAGAGAGAGGAGATCAGGGAGG +ACTTCCTGCAGGAAGTGATGCCGAAAATGAGATCTGACCGGTGACTAAGCTATACAAAAG +GGTGGGGTGGGGGAGCAAGTGGGGAGTGCTCTGGGCAGAAGGACCAGTCGTTCAGTCTGG +CTAGGGTAATTGTCATTCATTCATTTATTCACCAAGTATTTATTGGGCATCCACTGAATG +CCAGGCTTTGGGCTAAACCATGAGATGGAGCAATGAATAAGACAATGAGGCCCAGCCACA +AAATAGTTTATCCTCTAGTTGGGGGAGACAGGCAATGCACACACACAAAACAAACAGATC +AGAAAGGTGGCAGGAGGCCAGGCGCGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAG +GCCAAGGAGGGGGAGGCGGGGGGAGATCACCTGAGGTCAGGAGTTCGAGACCAGCCTGGC +CAACTTGGCGAAAACCCGTCTCTACTAAAAATATAAAAATTAGCTGGGCGTGGTGGTGGG +CACCTATAATCCCAGCTACTTGGGAAGCTGAGGTGAGAGAATTGCTTGAACCTAGAAGGC +AGAGGTTGCAGTGAGCCGAGATCTCGCCACTGCACTCCGGCCTGGGTGACAGAGCAAGAG +CAAGACTGTCTC diff --git a/test/csq/ENST00000329454/ENST00000329454.fa.fai b/test/csq/ENST00000329454/ENST00000329454.fa.fai new file mode 100644 index 0000000..c67dd06 --- /dev/null +++ b/test/csq/ENST00000329454/ENST00000329454.fa.fai @@ -0,0 +1 @@ +1 4572 23 60 61 diff --git a/test/csq/ENST00000329454/ENST00000329454.gff b/test/csq/ENST00000329454/ENST00000329454.gff new file mode 100644 index 0000000..97d2ebb --- /dev/null +++ b/test/csq/ENST00000329454/ENST00000329454.gff @@ -0,0 +1,8 @@ +1 ensembl_havana gene 1 4572 . + . ID=gene:ENSG00000183888;Name=C1orf64;biotype=protein_coding;description=chromosome 1 open reading frame 64 [Source:HGNC Symbol%3BAcc:28339];gene_id=ENSG00000183888;logic_name=ensembl_havana_gene;version=4 +1 ensembl_havana transcript 1 4572 . + . ID=transcript:ENST00000329454;Parent=gene:ENSG00000183888;Name=C1orf64-001;biotype=protein_coding;ccdsid=CCDS166.1;havana_transcript=OTTHUMT00000026317;havana_version=1;tag=basic;transcript_id=ENST00000329454;version=2 +1 ensembl_havana five_prime_UTR 1 68 . + . Parent=transcript:ENST00000329454 +1 ensembl_havana exon 1 150 . + . Parent=transcript:ENST00000329454;Name=ENSE00001310857;constitutive=1;ensembl_end_phase=1;ensembl_phase=-1;exon_id=ENSE00001310857;rank=1;version=2 +1 ensembl_havana CDS 69 150 . + 0 ID=CDS:ENSP00000332162;Parent=transcript:ENST00000329454;protein_id=ENSP00000332162 +1 ensembl_havana CDS 1684 2111 . + 2 ID=CDS:ENSP00000332162;Parent=transcript:ENST00000329454;protein_id=ENSP00000332162 +1 ensembl_havana exon 1684 4572 . + . Parent=transcript:ENST00000329454;Name=ENSE00001294049;constitutive=1;ensembl_end_phase=-1;ensembl_phase=1;exon_id=ENSE00001294049;rank=2;version=3 +1 ensembl_havana three_prime_UTR 2112 4572 . + . Parent=transcript:ENST00000329454 diff --git a/test/csq/ENST00000329454/boundary-deletion.txt b/test/csq/ENST00000329454/boundary-deletion.txt new file mode 100644 index 0000000..63da4f5 --- /dev/null +++ b/test/csq/ENST00000329454/boundary-deletion.txt @@ -0,0 +1,3 @@ +4572 CA C . +4572 CA C . + diff --git a/test/csq/ENST00000329454/boundary-deletion.txt-l b/test/csq/ENST00000329454/boundary-deletion.txt-l new file mode 100644 index 0000000..63da4f5 --- /dev/null +++ b/test/csq/ENST00000329454/boundary-deletion.txt-l @@ -0,0 +1,3 @@ +4572 CA C . +4572 CA C . + diff --git a/test/csq/ENST00000329454/boundary-deletion.vcf b/test/csq/ENST00000329454/boundary-deletion.vcf new file mode 100644 index 0000000..0f7dca3 --- /dev/null +++ b/test/csq/ENST00000329454/boundary-deletion.vcf @@ -0,0 +1,6 @@ +##fileformat=VCFv4.2 +##contig= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO +1 4572 . CA C . . EXP=.;type=ENST00000329454:16335302-CA-C just after diff --git a/test/csq/ENST00000341065/ENST00000341065.fa b/test/csq/ENST00000341065/ENST00000341065.fa new file mode 100644 index 0000000..28d6d00 --- /dev/null +++ b/test/csq/ENST00000341065/ENST00000341065.fa @@ -0,0 +1,330 @@ +>1 1:860260-879955 +CCAACGAGTTCCAGTTCGTCAGCGGCCGCGAGACGGCCAAGGACTGGAAGCGCAGCATCC +GCCACAAAGGTGCCGCCGCCCCTCCCTTCGCTGCCGGGACCCGCGGGCCCCGACCCCACC +CCCTACCCGACTCGGACACCCGGGAGCCTCCGGCTCGGCCGAGGGGGCGCTGCAGCTCCA +GGGCTGCGCGGGGACACCCCCGCCGCGCGCGGAGGCCTCGGTGAACACGGACAGATCGCC +CCCCGCTGCACCTCCCCCCAGCTTGGGCCACAGCGCTTGGGGCTCGCGGGCCGCTCCCTC +CGCTCGGAAGGTCTCTGCGAGGCTCCTGGGCCTTAAGGCCCGAAGGAAGTTTACGGGGAC +TCGAGAGAGCGGGCAGGAGGCGGGTTGGGAGGGCGCGGAGCCCCGGGTTCGGGGGAGACT +GGAGGGGCGCACGTGCGGCCGGGTGCGAGCGCGCGGCGGGGGAGGCTGCGGGGCGGCGCG +GGGGCGCGCGCGGAGCCCGAGCGGCGGCGCCAGGTCACACAACCTGTTTTGGCGCCTGCG +GGCGCCTGGGCCCAAGGGTGCGACGCGGGGGCGCCTGAGCCGGGACACAGGGGGTGCGGT +GAGCGCCAGGCGCCGCGGGGAGTTAAAAAGTTCGGGACCTGAGCGGTGCGTGGTTCCGCG +GTGGCCGCCTCTTCCTGCCGCGCAGGCCGAGGGTCCCGACGGCGCCGCTCACCGCTCCGG +GACTCAGCCTTTCTGGGCCCGGCCTGCGGTTCCCTCGGGGCCGGGGAGAGGGTGGAGCGC +GGGAGGAGGGGCGCCGGGTGGGGACGCCCAGGCCCTTCGTCGGGGGAGGGCGCTCCACCC +GGGCTGGAGTTGCAGAGCCCAGCAGATCCCTGCGGCGTTCGCGAGGGTGGGACGGGAAGC +GGGCTGGGAAGTCGGGCCGAGGTGGGTGTGGGGTTCGGGGTGTATTTCGTCCACGAGCCG +GGGAGGGGGTACTGGCCCTGCCGCTGACTGCGCGCAGAAGCGTGCCGCTCCCTCACAGGG +TCTGCCTCGGCTCTGCTCGCAGGGAAAAGTCTGAAGACGCTTATGTCCAAGGGGATCCTG +CAGGTGCATCCTCCGATCTGCGACTGCCCGGGCTGCCGAATATCCTCCCCGGTGGTGAGA +TGCGGGGCTCGGTTGGGGCTGGGAGTTACTCTCCCCTGCGGAGCTTGTCCCTGCGGTTTT +CAGGGTTTTCAGGATCGAGAGTCCTAACCTCACCCCTGCGGGTGTGCTGGAGGGAGCCTC +CGAAGGGCAGGGGGAAGCGGCTTTACCTCGTGCTCTCCCAGCCCTTCTACCTGGACGGGG +GAGGAGTCCTCGGGCACCCGAGCGCCCTCCCCGGTGGAGACAGGGGGGCCGCGCTTGTCT +TAGAGCCTCCCCTTGGGTGCCTTTTAGCTGCTTATCCTCGAGTCCTGGGTCAGGGTCTTC +TCCCTGGGAGGAGTAATTCAACGTGGGCCTGGCACTGTGCCCTGTCACCGCTTGGGGGTC +ACCGTGTTCTCTGGCCCAGCTGGTGAGGTGTGATTCTGGGACGACAGCATTTTGGGGAGC +TACAGGCTTGGGTGTGAGTGACTTGTGTCTCTGGGTGCTGAAGGCCAGAGGGTGCAAGGG +CCTGGACGTCGAAGTGTGTCCTAGGGACGCAGAGGCTAGCCAGGGGCAGAGTCTTTGCAG +TGTGGGCCTTTGGTGTCCAGGGAACTGGAGTCGGAGGCTGGTTCAAGGCCCCAACCCAGG +GTAGACAGCTATGGACACCCTCACTGAGGGAGCAGGCAGGAGAGACGGGGATGCTGGGAG +CTGCCTTCTGCTCAGGGAGGCACCTGCACCCCCTACCCAGTCTCCAGCCCCCTAGTTGGG +CAGCAAGGGTTAGAGGATTGATCTGAAAAGGAAGAATGCCTGTTGGGAAGGACTAGTTTG +GAGCCAATTAGGGCCATGGCTGCTGGGGGTGGGGGCTGCAATTCCTGACACACTCAGGAA +CCCCTTCTTCCAGGAAAGGGTAGGAGAGGCAGAGGTGCAAAATGGGCCTGAGGGTCCCGG +GCGTACCTCCGCTTGCCTGCTTTGGGCCTGAGGTAGGATGGGGGAGGGGATGCCCAGGGG +CCTGTGAGCCATGAGTGCCGTAGCCAGGGAGCTGGGCGGCTGCAGACACACCTGTGAAGA +CGGCTGGTCCCTCAGACATACAGCATGTTGGGCAGGGGAAGGGGACACAGCCGCACCTCA +CCCATGTGCCCACCTGACACACAATCCGACATGGACCTGCACGCACAGGCAGGCAGCTCA +CAGAGTTCCCAGGCAGGTGTGCAGACAGCCGGCAGCCCCCTGTCTGCTGTCACAGACCTA +CCCGGGGCAAGAGGCCCAGTTCCCTCCTTTCAAGCAGCTGGTGCTGGAGAGGGCTCCTCT +GGGCAGCCCGCTGCCTAGCCTTGGGTCTCTGTTTGGATTTGAGCGGCCCCCTTGAGGGCT +CCCCCAGGAGTGGGGAGCACACAGCCTGAGCCCAGCGTCAGTCTCTTCCGACAGTGCTTC +CGTGAGCATCTCCTCCCCACCCCGTGGCCACAGCCAGGAGATGCCCCCCCACCTGGGGCT 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+CCTCCAGGCACCCGGCTCCCCTTCGGGGAAGAGCTTTTCCCGACACTTCCTCGCCCAGCA +TCTTGTCTGCCGTCTCGGCCCTGTGGCCGCCCATCCTCCTGCCCCGTGCCCGAGACCAGC +CCAGGGGCCGAGCACGGCCGAGTGGTGTGGTCAGTTCCCCACCTCAGTGTTCTACGCCAG +GACGCGGGCTGGGGAGGATGAGGGCGCATAGCCGGGGGGATCACTGCTGTTGTCCCCCAC +CCAGATCTCCTGAGGGTCCGGCAGGAGGTGGCGGCTGCAGCTCTGAGGGGCCCCAGTGGC +CTGGAAGCCCACCTGCCCTCCTCCACGGCAGGTCAGCGTCGGAAGCAGGGCCTGGCTCAG +CACCGGGAGGGCGCCGCCCCAGCTGCCGCCCCGTCCTTCTCGGAGAGGTACTGGGGTGGC +TGCCGTTCTCTGCTTGTTTCTGGGGTGCCGCCCGCACCCCCGCGCTCTCAGCCACCAGCA +CGCGCCCCGAGAGTGCCAAGCACTGTGTTCAGCTCTAGGTTCGGGTCCGGGCAGAGCGTT +TCGGGGGTGACACCGATCTGGGCTGCAGTGTTGAGGGCGCCACTGGGGTGCGTGAGGGAG +GCTGAGGCCCATCAGGGGGTTCCCTGGAGGAGAAGCCAGAGAAGGGGAGAGCTCCAAGTC +TGGAACCCCGGGGTCAGTCGGGAGGGGTCGGCCAGAGGACTCAGAGCTGGAGGCGGAGGG +GGGGTCCTGGCTGGCGCTCAAATGTAGACGCCGGCGCCGGATCTGTTCCCGGCACAGACA +AGGCCTCCGGCACAGACCCGGGTTTCTCGGGTCCAGGACACGAGGCGGGGCGGGGCGCCT +GGAGAAGGGAGGGGCCGCCTGAGGCCCGAGTCCCTGCCCGGCCGCTGAGCCCGGCGTCTG +CAGCTGCCTCCACCGCCGCCCGGATTGCGGCTAATGACGCCCCCGCTTCCCCCGCCGCTC +GGGTCCGCAGGGGAGGGGAGCAGGCGGGGCCGGCGCCCCGCGCAGTAATTACCGCTGCAG +CCGTCGCCGCCCGCCGGGTCAGCGCCTCCGCGCCGCCGCCGAGATTAATTGGCGCCGCCG +GCGGGGGCGGGGATGGCGCGCGACCTGGGGCCGTAACGAGCTGCGCATCGACCGCCCGCG +GGGCCGGCAATTAGCGGAGGCGGCGGGGGAGGGGCGCCGGGGCCTTTACGGGAACGGGGG +CGGGGGGGACGCCGCTCATTGCGCTGCCGTCCACAGGGAGCTGCCTCAGCCGCCCCCCTT +GCTGTCGCCGCAGAATGCCCCTCACGTCGCCCTGGGCCCCCATCTCAGGCCCCCCTTCCT +GGGGGTGCCCTCGGCTCTGTGCCAGACCCCAGGTGAGGAGGCGGGTGCGCATCCCCTGGG +AGCCCGCGTGGAGGCTCGCGGACCCGGCCCTGCCCCTGTCGGAGCCGAGACGGACCGGGT +AGGGGATTGCAAAGGGCCGGCTCGGACCGCCTCGGACCCCCCGACCCCGCGTTGTCCCCC +TCCCCACCAGGCTACGGCTTCCTGCCCCCCGCGCAGGCGGAGATGTTCGCCTGGCAGCAG +GAGCTCCTGCGGAAGCAGAACCTGGCCCGGTAGGTGCGGGGAGGCGGGCGGGGCCGCGCG +GCCCGGGAGGCGGCTGACCCGCGTCTGCCCCCGGCCCAGGCTGGAGCTGCCCGCCGACCT +CCTGCGGCAGAAGGAGCTGGAGAGCGCGCGCCCACAGCTGCTGGCGCCCGAGACCGCCCT +GCGCCCCAACGACGGCGCCGAGGAGCTGCAGCGGCGCGGGGCCCTGCTGGTGCTGAACCA +CGGCGCGGCGCCACTGCTGGCCCTGCCCCCCCAGGGGCCCCCGGGCTCCGGACCCCCCAC +CCCGTCCCGGGACTCTGCCCGGCGAGCCCCCCGGAAGGGGGGTCCCGGCCCTGCCTCAGC +GCGGCCCAGCGAGTCCAAGGAGATGACGGGGGCTAGGCTCTGGGCACAAGATGGCTCGGA +AGACGAGCCCCCCAAAGACTCGGACGGAGAGGACCCCGAGACGGCAGCTGTTGGGTGCAG +GGGGCCCACTCCGGGCCAAGCTCCAGCTGGAGGGGCCGGCGCCGAGGGGAAGGGGCTTTT +CCCAGGGTCCACACTGCCCCTGGGCTTCCCTTATGCCGTCAGCCCCTACTTCCACACAGG +TGGGCACCCCCACACTCTAGATCCTTCCAGAGGGCACAGGACTGGCAGGCCGCCTGTGGA +AGGGTCTTGGGGGGAGGAAAAATTCCCCTTAGGCACCCATCCCCCACCTCAGCAATTGGG +GCACACGACGGTCAGGAGACGGGCGGGTATGGGAAAGCCAGCCAGAGCCCTAGTAACACG +CCCCACAACTCAGGCGCGGTAGGGGGACTCTCCATGGATGGGGAGGAGGCCCCAGCCCCT +GAGGACGTCACCAAGTGGACCGTGGATGACGTCTGCAGCTTCGTGGGGGGCCTGTCTGGC +TGTGGAGAGTACACTCGGGTAAGGGGGGGCCCCAGTTCCTGGGGCGGGGCTGGAGCTGGC +TGGCAGTCACTACCTCCCTGGAAAGGATGGTGGGGTAGGGCCATTCCCCAACGCCCTCTC +CCTCCCCAAAAGCAGTGCGCAGCAGGGACTGGACTGTGCACCCCACCTTTTTTTTTTTTT +TTTTTTTTTGCCAGGTGTTTTCTGCCTGACACTCAAACCCAACAGATCACTGTTTTTAAA +AAATTTCCGTGAGCTGCACAAACAGCTCCTCTTGGCTCTGCTGGGCTGGAGGATGGAGCA +GCACCCGGGTCCTGACCCTCCCTCCCTCCCCCTTCCAGGTCTTCAGGGAGCAGGGGATCG +ACGGGGAGACCCTGCCACTGCTGACGGAGGAGCACCTGCTGACCAACATGGGGCTGAAGC +TGGGGCCCGCCCTCAAGATCCGGGCCCAGGTGAGACGCTGGGGAGTGAGGTCAGGGTCTC +CAGACCACAGCTGGGCAGAAAGCTCTGGGTGGGTGTGCGACAGCCCCCACCAGGCCATCT +CTCTGCAGGTGGCCAGGCGCCTGGGCCGAGTTTTCTACGTGGCCAGCTTCCCCGTGGCTC +TGCCACTGCAGCCACCAACCCTGCGGGCCCCGGAGCGAGAACTCGGCACAGGAGAGCAGC +CCTTGTCCCCCACGACGGCCACGTCCCCCTATGGAGGGGGCCACGCCCTTGCCGGTCAAA +CTTCACCCAAGCAGGAGAATGGGACCTTGGCTCTACTTCCAGGGGCCCCCGACCCTTCCC +AGCCTCTGTGTTGAGGTTGCCGGGGGTAGGGGTGGGGCCACACAAATCTCCAGGAGCCAC +CACTCAACACAATGGCCCTGCCTCCCACCGCTTTATTTCTTTCGGTTTCGGATGCAAAAC +AAAAAATTTTAAAAGAAAATGTGACTTCAAAGGAAAGGAACAAATTTTCAAAGACTTGGG +GGAGTGAAGGCAGAGCCTGGTGCAGATGGACGAGGTCTGCAGACGGAGGGCAGAGGTGGT +GGAAGGGGCCAGGGGCCTGCAGGCCTCCCCCTGGAACTGGGACTGGTCTCGGTCTGCTGA +CGTCAGGGTCAGCTCCCCCGCGGAGCTGACTTCAGCAGCCCACAGCTGTGGGGCTTCAGC +AGCCACACCAGCCCAGCCCAGCCCAGCTCTCGATACGTTTGGTCTTTCATGCTGAAAAAT +AAATAATAAAGCCTGT diff --git a/test/csq/ENST00000341065/ENST00000341065.fa.fai b/test/csq/ENST00000341065/ENST00000341065.fa.fai new file mode 100644 index 0000000..fdd7550 --- /dev/null +++ b/test/csq/ENST00000341065/ENST00000341065.fa.fai @@ -0,0 +1 @@ +1 19696 19 60 61 diff --git a/test/csq/ENST00000341065/ENST00000341065.gff b/test/csq/ENST00000341065/ENST00000341065.gff new file mode 100644 index 0000000..7b085aa --- /dev/null +++ b/test/csq/ENST00000341065/ENST00000341065.gff @@ -0,0 +1,27 @@ +1 ensembl_havana gene 1 19696 . + . ID=gene:ENSG00000187634;Name=SAMD11;biotype=protein_coding;description=sterile alpha motif domain containing 11 [Source:HGNC Symbol%3BAcc:28706];gene_id=ENSG00000187634;logic_name=ensembl_havana_gene;version=6 +1 ensembl_havana transcript 5433 19696 . + . ID=transcript:ENST00000341065;Parent=gene:ENSG00000187634;Name=SAMD11-001;biotype=protein_coding;havana_transcript=OTTHUMT00000097860;havana_version=4;transcript_id=ENST00000341065;version=4 +1 havana exon 5433 5457 . + . Parent=transcript:ENST00000341065;Name=ENSE00001768193;constitutive=0;ensembl_end_phase=2;ensembl_phase=1;exon_id=ENSE00001768193;rank=1;version=1 +1 havana CDS 5433 5457 . + 2 ID=CDS:ENSP00000349216;Parent=transcript:ENST00000341065;protein_id=ENSP00000349216 +1 havana exon 6160 6210 . + . Parent=transcript:ENST00000341065;Name=ENSE00002696520;constitutive=0;ensembl_end_phase=2;ensembl_phase=2;exon_id=ENSE00002696520;rank=2;version=1 +1 havana CDS 6160 6210 . + 1 ID=CDS:ENSP00000349216;Parent=transcript:ENST00000341065;protein_id=ENSP00000349216 +1 havana exon 10893 11017 . + . Parent=transcript:ENST00000341065;Name=ENSE00002703998;constitutive=0;ensembl_end_phase=1;ensembl_phase=2;exon_id=ENSE00002703998;rank=3;version=1 +1 havana CDS 10893 11017 . + 1 ID=CDS:ENSP00000349216;Parent=transcript:ENST00000341065;protein_id=ENSP00000349216 +1 havana exon 14161 14250 . + . Parent=transcript:ENST00000341065;Name=ENSE00002686739;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00002686739;rank=4;version=1 +1 havana CDS 14161 14250 . + 2 ID=CDS:ENSP00000349216;Parent=transcript:ENST00000341065;protein_id=ENSP00000349216 +1 havana exon 14396 14533 . + . Parent=transcript:ENST00000341065;Name=ENSE00001708361;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00001708361;rank=5;version=1 +1 havana CDS 14396 14533 . + 2 ID=CDS:ENSP00000349216;Parent=transcript:ENST00000341065;protein_id=ENSP00000349216 +1 havana exon 16265 16427 . + . Parent=transcript:ENST00000341065;Name=ENSE00003477353;constitutive=0;ensembl_end_phase=2;ensembl_phase=1;exon_id=ENSE00003477353;rank=6;version=1 +1 havana CDS 16265 16427 . + 2 ID=CDS:ENSP00000349216;Parent=transcript:ENST00000341065;protein_id=ENSP00000349216 +1 havana exon 17257 17372 . + . Parent=transcript:ENST00000341065;Name=ENSE00003681266;constitutive=0;ensembl_end_phase=1;ensembl_phase=2;exon_id=ENSE00003681266;rank=7;version=1 +1 havana CDS 17257 17372 . + 1 ID=CDS:ENSP00000349216;Parent=transcript:ENST00000341065;protein_id=ENSP00000349216 +1 havana exon 17531 17609 . + . Parent=transcript:ENST00000341065;Name=ENSE00003675531;constitutive=0;ensembl_end_phase=2;ensembl_phase=1;exon_id=ENSE00003675531;rank=8;version=1 +1 havana CDS 17531 17609 . + 2 ID=CDS:ENSP00000349216;Parent=transcript:ENST00000341065;protein_id=ENSP00000349216 +1 havana exon 17680 18179 . + . Parent=transcript:ENST00000341065;Name=ENSE00002728091;constitutive=0;ensembl_end_phase=1;ensembl_phase=2;exon_id=ENSE00002728091;rank=9;version=1 +1 havana CDS 17680 18179 . + 1 ID=CDS:ENSP00000349216;Parent=transcript:ENST00000341065;protein_id=ENSP00000349216 +1 havana exon 18374 18498 . + . Parent=transcript:ENST00000341065;Name=ENSE00002733131;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00002733131;rank=10;version=1 +1 havana CDS 18374 18498 . + 2 ID=CDS:ENSP00000349216;Parent=transcript:ENST00000341065;protein_id=ENSP00000349216 +1 havana exon 18819 18929 . + . Parent=transcript:ENST00000341065;Name=ENSE00002692620;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00002692620;rank=11;version=1 +1 havana CDS 18819 18929 . + 0 ID=CDS:ENSP00000349216;Parent=transcript:ENST00000341065;protein_id=ENSP00000349216 +1 havana CDS 19029 19274 . + 0 ID=CDS:ENSP00000349216;Parent=transcript:ENST00000341065;protein_id=ENSP00000349216 +1 havana exon 19029 19696 . + . Parent=transcript:ENST00000341065;Name=ENSE00001804027;constitutive=0;ensembl_end_phase=-1;ensembl_phase=0;exon_id=ENSE00001804027;rank=12;version=1 +1 havana three_prime_UTR 19275 19696 . + . Parent=transcript:ENST00000341065 diff --git a/test/csq/ENST00000341065/ascii-art.txt b/test/csq/ENST00000341065/ascii-art.txt new file mode 100644 index 0000000..cfa5b49 --- /dev/null +++ b/test/csq/ENST00000341065/ascii-art.txt @@ -0,0 +1,61 @@ + 16257 16265 16427 +56789012345 7890 +CCCCACCCAGA-------------GGTACTGGGGTG + CCAGA + C-AGA + CCCACCCAg + CCCACC-AG + ......ooXXXXXXXXXXXXXXXoo...... +09876543210 01234567890 +CCC GGTACTGGG- +CC- GGTACT-GGG +-CC + + +GGTACTGGGGTG + T- + + + 18374 18498 +45678901234 890123456 +CACAACTCAGG-------GGTAAGGGGGGGC + ......ooXXXXXXXXXoo...... +09876543210 01234567890 + Axx Cxx Tx + + 18819 18826 +901234567890123456789 +CCCCTTCCAGGTCTTCAGGGA + CAGGTCT A + ......ooXXXXXXXXXoo...... + 0123 + + + 19029 19274 +CTCTCTGCAGGTGGCCAGG + CAGGTG---AG + CAGGT---CAG + CAGG---CCAG + CAG---GCCAG + ......ooXXXXXXXXXoo...... + + 19030 + GTGGCCAGG + -V--A--R- + 509 + GTG---AGG + -V-----R- + + GT---CAGG + -V-----R- + + G---CCAGG + -V-----R- + + 19026 + + V A R + cagGTG.GCC.AGg + cagGT-.--C.AGg V-R + cagG--.-CC.AGg A-R + cag---.GCC.AGg A-R diff --git a/test/csq/ENST00000341065/ascii-art.txt-l b/test/csq/ENST00000341065/ascii-art.txt-l new file mode 100644 index 0000000..cfa5b49 --- /dev/null +++ b/test/csq/ENST00000341065/ascii-art.txt-l @@ -0,0 +1,61 @@ + 16257 16265 16427 +56789012345 7890 +CCCCACCCAGA-------------GGTACTGGGGTG + CCAGA + C-AGA + CCCACCCAg + CCCACC-AG + ......ooXXXXXXXXXXXXXXXoo...... +09876543210 01234567890 +CCC GGTACTGGG- +CC- GGTACT-GGG +-CC + + +GGTACTGGGGTG + T- + + + 18374 18498 +45678901234 890123456 +CACAACTCAGG-------GGTAAGGGGGGGC + ......ooXXXXXXXXXoo...... +09876543210 01234567890 + Axx Cxx Tx + + 18819 18826 +901234567890123456789 +CCCCTTCCAGGTCTTCAGGGA + CAGGTCT A + ......ooXXXXXXXXXoo...... + 0123 + + + 19029 19274 +CTCTCTGCAGGTGGCCAGG + CAGGTG---AG + CAGGT---CAG + CAGG---CCAG + CAG---GCCAG + ......ooXXXXXXXXXoo...... + + 19030 + GTGGCCAGG + -V--A--R- + 509 + GTG---AGG + -V-----R- + + GT---CAGG + -V-----R- + + G---CCAGG + -V-----R- + + 19026 + + V A R + cagGTG.GCC.AGg + cagGT-.--C.AGg V-R + cagG--.-CC.AGg A-R + cag---.GCC.AGg A-R diff --git a/test/csq/ENST00000341065/frame1.txt b/test/csq/ENST00000341065/frame1.txt new file mode 100644 index 0000000..583b692 --- /dev/null +++ b/test/csq/ENST00000341065/frame1.txt @@ -0,0 +1,3 @@ +19030 TGGC T inframe_deletion|SAMD11|ENST00000341065|protein_coding|+|508VA>508V|19030TGGC>T,splice_region|SAMD11|ENST00000341065|protein_coding +19030 TGGC T inframe_deletion|SAMD11|ENST00000341065|protein_coding|+|508VA>508V|19030TGGC>T,splice_region|SAMD11|ENST00000341065|protein_coding + diff --git a/test/csq/ENST00000341065/frame1.txt-l b/test/csq/ENST00000341065/frame1.txt-l new file mode 100644 index 0000000..583b692 --- /dev/null +++ b/test/csq/ENST00000341065/frame1.txt-l @@ -0,0 +1,3 @@ +19030 TGGC T inframe_deletion|SAMD11|ENST00000341065|protein_coding|+|508VA>508V|19030TGGC>T,splice_region|SAMD11|ENST00000341065|protein_coding +19030 TGGC T inframe_deletion|SAMD11|ENST00000341065|protein_coding|+|508VA>508V|19030TGGC>T,splice_region|SAMD11|ENST00000341065|protein_coding + diff --git a/test/csq/ENST00000341065/frame1.vcf b/test/csq/ENST00000341065/frame1.vcf new file mode 100644 index 0000000..ebcb5bb --- /dev/null +++ b/test/csq/ENST00000341065/frame1.vcf @@ -0,0 +1,6 @@ +##fileformat=VCFv4.2 +##contig= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO +1 19030 . TGGC T . . EXP=inframe_deletion|SAMD11|ENST00000341065|protein_coding|+|508VA>508V|19030TGGC>T,splice_region|SAMD11|ENST00000341065|protein_coding diff --git a/test/csq/ENST00000341065/frame2.txt b/test/csq/ENST00000341065/frame2.txt new file mode 100644 index 0000000..fc4bd55 --- /dev/null +++ b/test/csq/ENST00000341065/frame2.txt @@ -0,0 +1,3 @@ +19026 CAGGTGGCCAG CAGGTCAG inframe_deletion|SAMD11|ENST00000341065|protein_coding|+|508VA>508V|19026CAGGTGGCCAG>CAGGTCAG,splice_region|SAMD11|ENST00000341065|protein_coding +19026 CAGGTGGCCAG CAGGTCAG inframe_deletion|SAMD11|ENST00000341065|protein_coding|+|508VA>508V|19026CAGGTGGCCAG>CAGGTCAG,splice_region|SAMD11|ENST00000341065|protein_coding + diff --git a/test/csq/ENST00000341065/frame2.txt-l b/test/csq/ENST00000341065/frame2.txt-l new file mode 100644 index 0000000..fc4bd55 --- /dev/null +++ b/test/csq/ENST00000341065/frame2.txt-l @@ -0,0 +1,3 @@ +19026 CAGGTGGCCAG CAGGTCAG inframe_deletion|SAMD11|ENST00000341065|protein_coding|+|508VA>508V|19026CAGGTGGCCAG>CAGGTCAG,splice_region|SAMD11|ENST00000341065|protein_coding +19026 CAGGTGGCCAG CAGGTCAG inframe_deletion|SAMD11|ENST00000341065|protein_coding|+|508VA>508V|19026CAGGTGGCCAG>CAGGTCAG,splice_region|SAMD11|ENST00000341065|protein_coding + diff --git a/test/csq/ENST00000341065/frame2.vcf b/test/csq/ENST00000341065/frame2.vcf new file mode 100644 index 0000000..bbfddd8 --- /dev/null +++ b/test/csq/ENST00000341065/frame2.vcf @@ -0,0 +1,7 @@ +##fileformat=VCFv4.2 +##contig= +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO +1 19026 . CAGGTGGCCAG CAGGTCAG . . EXP=inframe_deletion|SAMD11|ENST00000341065|protein_coding|+|508VA>508V|19026CAGGTGGCCAG>CAGGTCAG,splice_region|SAMD11|ENST00000341065|protein_coding;type=first is X, so 508V is correct diff --git a/test/csq/ENST00000341065/frame3.txt b/test/csq/ENST00000341065/frame3.txt new file mode 100644 index 0000000..dad5688 --- /dev/null +++ b/test/csq/ENST00000341065/frame3.txt @@ -0,0 +1,3 @@ +19026 CAGGTGGCCAG CAGGCCAG inframe_deletion|SAMD11|ENST00000341065|protein_coding|+|508VA>508A|19026CAGGTGGCCAG>CAGGCCAG,synonymous&splice_acceptor|SAMD11|ENST00000341065|protein_coding +19026 CAGGTGGCCAG CAGGCCAG inframe_deletion|SAMD11|ENST00000341065|protein_coding|+|508VA>508A|19026CAGGTGGCCAG>CAGGCCAG,synonymous&splice_acceptor|SAMD11|ENST00000341065|protein_coding + diff --git a/test/csq/ENST00000341065/frame3.txt-l b/test/csq/ENST00000341065/frame3.txt-l new file mode 100644 index 0000000..dad5688 --- /dev/null +++ b/test/csq/ENST00000341065/frame3.txt-l @@ -0,0 +1,3 @@ +19026 CAGGTGGCCAG CAGGCCAG inframe_deletion|SAMD11|ENST00000341065|protein_coding|+|508VA>508A|19026CAGGTGGCCAG>CAGGCCAG,synonymous&splice_acceptor|SAMD11|ENST00000341065|protein_coding +19026 CAGGTGGCCAG CAGGCCAG inframe_deletion|SAMD11|ENST00000341065|protein_coding|+|508VA>508A|19026CAGGTGGCCAG>CAGGCCAG,synonymous&splice_acceptor|SAMD11|ENST00000341065|protein_coding + diff --git a/test/csq/ENST00000341065/frame3.vcf b/test/csq/ENST00000341065/frame3.vcf new file mode 100644 index 0000000..c45295c --- /dev/null +++ b/test/csq/ENST00000341065/frame3.vcf @@ -0,0 +1,6 @@ +##fileformat=VCFv4.2 +##contig= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO +1 19026 . CAGGTGGCCAG CAGGCCAG . . EXP=inframe_deletion|SAMD11|ENST00000341065|protein_coding|+|508VA>508A|19026CAGGTGGCCAG>CAGGCCAG,synonymous&splice_acceptor|SAMD11|ENST00000341065|protein_coding;type=879285-CAGGTGGCCAG-CAGGCCAG, correct is CAG---GCCAG, first codon deleted, synonymous acceptor diff --git a/test/csq/ENST00000341065/not-a-start-lost.txt b/test/csq/ENST00000341065/not-a-start-lost.txt new file mode 100644 index 0000000..97d1e2b --- /dev/null +++ b/test/csq/ENST00000341065/not-a-start-lost.txt @@ -0,0 +1,3 @@ +5435 C G missense|SAMD11|ENST00000341065|protein_coding|+|1H>1D|5435C>G +5435 C G missense|SAMD11|ENST00000341065|protein_coding|+|1H>1D|5435C>G + diff --git a/test/csq/ENST00000341065/not-a-start-lost.txt-l b/test/csq/ENST00000341065/not-a-start-lost.txt-l new file mode 100644 index 0000000..97d1e2b --- /dev/null +++ b/test/csq/ENST00000341065/not-a-start-lost.txt-l @@ -0,0 +1,3 @@ +5435 C G missense|SAMD11|ENST00000341065|protein_coding|+|1H>1D|5435C>G +5435 C G missense|SAMD11|ENST00000341065|protein_coding|+|1H>1D|5435C>G + diff --git a/test/csq/ENST00000341065/not-a-start-lost.vcf b/test/csq/ENST00000341065/not-a-start-lost.vcf new file mode 100644 index 0000000..2b6813e --- /dev/null +++ b/test/csq/ENST00000341065/not-a-start-lost.vcf @@ -0,0 +1,6 @@ +##fileformat=VCFv4.2 +##contig= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO +1 5435 . C G . . EXP=missense|SAMD11|ENST00000341065|protein_coding|+|1H>1D|5435C>G;type=ENST00000341065:865694-C-G:incomplete cds diff --git a/test/csq/ENST00000341065/splice-acceptor-donor1.txt b/test/csq/ENST00000341065/splice-acceptor-donor1.txt new file mode 100644 index 0000000..6c5b1f1 --- /dev/null +++ b/test/csq/ENST00000341065/splice-acceptor-donor1.txt @@ -0,0 +1,33 @@ +16255 CCC CC intron|SAMD11||protein_coding +16255 CCC CC intron|SAMD11||protein_coding + +16261 CCA CA splice_region|SAMD11|ENST00000341065|protein_coding +16261 CCA CA splice_region|SAMD11|ENST00000341065|protein_coding + +16429 TA T splice_region|SAMD11|ENST00000341065|protein_coding +16429 TA T splice_region|SAMD11|ENST00000341065|protein_coding + +16438 GG G intron|SAMD11||protein_coding +16438 GG G intron|SAMD11||protein_coding + +18365 A AA intron|SAMD11||protein_coding +18365 A AA intron|SAMD11||protein_coding + +18371 C CA splice_region|SAMD11|ENST00000341065|protein_coding +18371 C CA splice_region|SAMD11|ENST00000341065|protein_coding + +18500 T TA splice_region|SAMD11|ENST00000341065|protein_coding +18500 T TA splice_region|SAMD11|ENST00000341065|protein_coding + +18506 G GA intron|SAMD11||protein_coding +18506 G GA intron|SAMD11||protein_coding + +18816 CAGGTCT CAGGTCT . +18816 CAGGTCT CAGGTCT . + +18826 G A missense|SAMD11|ENST00000341065|protein_coding|+|473R>473K|18826G>A +18826 G A missense|SAMD11|ENST00000341065|protein_coding|+|473R>473K|18826G>A + +19026 CAGGTGGCCAG CAGGTGAG inframe_deletion|SAMD11|ENST00000341065|protein_coding|+|508VA>508V|19026CAGGTGGCCAG>CAGGTGAG +19026 CAGGTGGCCAG CAGGTGAG inframe_deletion|SAMD11|ENST00000341065|protein_coding|+|508VA>508V|19026CAGGTGGCCAG>CAGGTGAG + diff --git a/test/csq/ENST00000341065/splice-acceptor-donor1.txt-l b/test/csq/ENST00000341065/splice-acceptor-donor1.txt-l new file mode 100644 index 0000000..6c5b1f1 --- /dev/null +++ b/test/csq/ENST00000341065/splice-acceptor-donor1.txt-l @@ -0,0 +1,33 @@ +16255 CCC CC intron|SAMD11||protein_coding +16255 CCC CC intron|SAMD11||protein_coding + +16261 CCA CA splice_region|SAMD11|ENST00000341065|protein_coding +16261 CCA CA splice_region|SAMD11|ENST00000341065|protein_coding + +16429 TA T splice_region|SAMD11|ENST00000341065|protein_coding +16429 TA T splice_region|SAMD11|ENST00000341065|protein_coding + +16438 GG G intron|SAMD11||protein_coding +16438 GG G intron|SAMD11||protein_coding + +18365 A AA intron|SAMD11||protein_coding +18365 A AA intron|SAMD11||protein_coding + +18371 C CA splice_region|SAMD11|ENST00000341065|protein_coding +18371 C CA splice_region|SAMD11|ENST00000341065|protein_coding + +18500 T TA splice_region|SAMD11|ENST00000341065|protein_coding +18500 T TA splice_region|SAMD11|ENST00000341065|protein_coding + +18506 G GA intron|SAMD11||protein_coding +18506 G GA intron|SAMD11||protein_coding + +18816 CAGGTCT CAGGTCT . +18816 CAGGTCT CAGGTCT . + +18826 G A missense|SAMD11|ENST00000341065|protein_coding|+|473R>473K|18826G>A +18826 G A missense|SAMD11|ENST00000341065|protein_coding|+|473R>473K|18826G>A + +19026 CAGGTGGCCAG CAGGTGAG inframe_deletion|SAMD11|ENST00000341065|protein_coding|+|508VA>508V|19026CAGGTGGCCAG>CAGGTGAG +19026 CAGGTGGCCAG CAGGTGAG inframe_deletion|SAMD11|ENST00000341065|protein_coding|+|508VA>508V|19026CAGGTGGCCAG>CAGGTGAG + diff --git a/test/csq/ENST00000341065/splice-acceptor-donor1.vcf b/test/csq/ENST00000341065/splice-acceptor-donor1.vcf new file mode 100644 index 0000000..b9526df --- /dev/null +++ b/test/csq/ENST00000341065/splice-acceptor-donor1.vcf @@ -0,0 +1,16 @@ +##fileformat=VCFv4.2 +##contig= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO +1 16255 . CCC CC . . EXP=intron|SAMD11||protein_coding;type=splice should not be called, can be normalized +1 16261 . CCA CA . . EXP=splice_region|SAMD11|ENST00000341065|protein_coding;type=splice_region but not splice_acceptor +1 16429 . TA T . . EXP=splice_region|SAMD11|ENST00000341065|protein_coding;type=splice_region but not splice_donor +1 16438 . GG G . . EXP=intron|SAMD11||protein_coding;type=splice should not be called +1 18365 . A AA . . EXP=intron|SAMD11||protein_coding;type=same as 16255 but an insertion +1 18371 . C CA . . EXP=splice_region|SAMD11|ENST00000341065|protein_coding;type=same as 16261 but an insertion +1 18500 . T TA . . EXP=splice_region|SAMD11|ENST00000341065|protein_coding;type=same as 16429 but an insertion +1 18506 . G GA . . EXP=intron|SAMD11||protein_coding;type=same as 16438 but an insertion +1 18816 . CAGGTCT CAGGTCT . . EXP=.;type=ref not a variant +1 18826 . G A . . EXP=missense|SAMD11|ENST00000341065|protein_coding|+|473R>473K|18826G>A +1 19026 . CAGGTGGCCAG CAGGTGAG . . EXP=inframe_deletion|SAMD11|ENST00000341065|protein_coding|+|508VA>508V|19026CAGGTGGCCAG>CAGGTGAG;type=indel inside exon not splice diff --git a/test/csq/ENST00000341065/splice-acceptor-donor2.txt b/test/csq/ENST00000341065/splice-acceptor-donor2.txt new file mode 100644 index 0000000..fd14bdb --- /dev/null +++ b/test/csq/ENST00000341065/splice-acceptor-donor2.txt @@ -0,0 +1,3 @@ +16255 CCCCACCCAGA CCCACCCAGA . +16255 CCCCACCCAGA CCCACCCAGA . + diff --git a/test/csq/ENST00000341065/splice-acceptor-donor2.txt-l b/test/csq/ENST00000341065/splice-acceptor-donor2.txt-l new file mode 100644 index 0000000..fd14bdb --- /dev/null +++ b/test/csq/ENST00000341065/splice-acceptor-donor2.txt-l @@ -0,0 +1,3 @@ +16255 CCCCACCCAGA CCCACCCAGA . +16255 CCCCACCCAGA CCCACCCAGA . + diff --git a/test/csq/ENST00000341065/splice-acceptor-donor2.vcf b/test/csq/ENST00000341065/splice-acceptor-donor2.vcf new file mode 100644 index 0000000..1fb5dcc --- /dev/null +++ b/test/csq/ENST00000341065/splice-acceptor-donor2.vcf @@ -0,0 +1,6 @@ +##fileformat=VCFv4.2 +##contig= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO +1 16255 . CCCCACCCAGA CCCACCCAGA . . EXP=.;type=should not be called, can be normalized diff --git a/test/csq/ENST00000341065/splice-acceptor-donor3.txt b/test/csq/ENST00000341065/splice-acceptor-donor3.txt new file mode 100644 index 0000000..c13bb02 --- /dev/null +++ b/test/csq/ENST00000341065/splice-acceptor-donor3.txt @@ -0,0 +1,3 @@ +16261 CCAGA CAGA splice_region|SAMD11|ENST00000341065|protein_coding +16261 CCAGA CAGA splice_region|SAMD11|ENST00000341065|protein_coding + diff --git a/test/csq/ENST00000341065/splice-acceptor-donor3.txt-l b/test/csq/ENST00000341065/splice-acceptor-donor3.txt-l new file mode 100644 index 0000000..c13bb02 --- /dev/null +++ b/test/csq/ENST00000341065/splice-acceptor-donor3.txt-l @@ -0,0 +1,3 @@ +16261 CCAGA CAGA splice_region|SAMD11|ENST00000341065|protein_coding +16261 CCAGA CAGA splice_region|SAMD11|ENST00000341065|protein_coding + diff --git a/test/csq/ENST00000341065/splice-acceptor-donor3.vcf b/test/csq/ENST00000341065/splice-acceptor-donor3.vcf new file mode 100644 index 0000000..0375aca --- /dev/null +++ b/test/csq/ENST00000341065/splice-acceptor-donor3.vcf @@ -0,0 +1,6 @@ +##fileformat=VCFv4.2 +##contig= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO +1 16261 . CCAGA CAGA . . EXP=splice_region|SAMD11|ENST00000341065|protein_coding;type=CCAG[A>C-AGA[A, splice_region but not splice_acceptor,non-synon region diff --git a/test/csq/ENST00000341065/splice-acceptor-donor4.txt b/test/csq/ENST00000341065/splice-acceptor-donor4.txt new file mode 100644 index 0000000..15e2ce5 --- /dev/null +++ b/test/csq/ENST00000341065/splice-acceptor-donor4.txt @@ -0,0 +1,3 @@ +16427 GGTA GGT splice_region|SAMD11|ENST00000341065|protein_coding +16427 GGTA GGT splice_region|SAMD11|ENST00000341065|protein_coding + diff --git a/test/csq/ENST00000341065/splice-acceptor-donor4.txt-l b/test/csq/ENST00000341065/splice-acceptor-donor4.txt-l new file mode 100644 index 0000000..15e2ce5 --- /dev/null +++ b/test/csq/ENST00000341065/splice-acceptor-donor4.txt-l @@ -0,0 +1,3 @@ +16427 GGTA GGT splice_region|SAMD11|ENST00000341065|protein_coding +16427 GGTA GGT splice_region|SAMD11|ENST00000341065|protein_coding + diff --git a/test/csq/ENST00000341065/splice-acceptor-donor4.vcf b/test/csq/ENST00000341065/splice-acceptor-donor4.vcf new file mode 100644 index 0000000..003c9be --- /dev/null +++ b/test/csq/ENST00000341065/splice-acceptor-donor4.vcf @@ -0,0 +1,6 @@ +##fileformat=VCFv4.2 +##contig= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO +1 16427 . GGTA GGT . . EXP=splice_region|SAMD11|ENST00000341065|protein_coding;type=splice_region but not splice_donor diff --git a/test/csq/ENST00000341065/splice-acceptor-donor5.txt b/test/csq/ENST00000341065/splice-acceptor-donor5.txt new file mode 100644 index 0000000..844a294 --- /dev/null +++ b/test/csq/ENST00000341065/splice-acceptor-donor5.txt @@ -0,0 +1,3 @@ +16427 GGTACTGGGG GGTACTGGG synonymous&splice_region|SAMD11|ENST00000341065|protein_coding +16427 GGTACTGGGG GGTACTGGG synonymous&splice_region|SAMD11|ENST00000341065|protein_coding + diff --git a/test/csq/ENST00000341065/splice-acceptor-donor5.txt-l b/test/csq/ENST00000341065/splice-acceptor-donor5.txt-l new file mode 100644 index 0000000..844a294 --- /dev/null +++ b/test/csq/ENST00000341065/splice-acceptor-donor5.txt-l @@ -0,0 +1,3 @@ +16427 GGTACTGGGG GGTACTGGG synonymous&splice_region|SAMD11|ENST00000341065|protein_coding +16427 GGTACTGGGG GGTACTGGG synonymous&splice_region|SAMD11|ENST00000341065|protein_coding + diff --git a/test/csq/ENST00000341065/splice-acceptor-donor5.vcf b/test/csq/ENST00000341065/splice-acceptor-donor5.vcf new file mode 100644 index 0000000..7a4a29a --- /dev/null +++ b/test/csq/ENST00000341065/splice-acceptor-donor5.vcf @@ -0,0 +1,6 @@ +##fileformat=VCFv4.2 +##contig= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO +1 16427 . GGTACTGGGG GGTACTGGG . . EXP=synonymous&splice_region|SAMD11|ENST00000341065|protein_coding;type=should not be called diff --git a/test/csq/ENST00000341065/splice-acceptor-donor6.txt b/test/csq/ENST00000341065/splice-acceptor-donor6.txt new file mode 100644 index 0000000..a2a60e5 --- /dev/null +++ b/test/csq/ENST00000341065/splice-acceptor-donor6.txt @@ -0,0 +1,3 @@ +18365 ACAACTCAGG AACAACTCAGG . +18365 ACAACTCAGG AACAACTCAGG . + diff --git a/test/csq/ENST00000341065/splice-acceptor-donor6.txt-l b/test/csq/ENST00000341065/splice-acceptor-donor6.txt-l new file mode 100644 index 0000000..a2a60e5 --- /dev/null +++ b/test/csq/ENST00000341065/splice-acceptor-donor6.txt-l @@ -0,0 +1,3 @@ +18365 ACAACTCAGG AACAACTCAGG . +18365 ACAACTCAGG AACAACTCAGG . + diff --git a/test/csq/ENST00000341065/splice-acceptor-donor6.vcf b/test/csq/ENST00000341065/splice-acceptor-donor6.vcf new file mode 100644 index 0000000..4703db8 --- /dev/null +++ b/test/csq/ENST00000341065/splice-acceptor-donor6.vcf @@ -0,0 +1,6 @@ +##fileformat=VCFv4.2 +##contig= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO +1 18365 . ACAACTCAGG AACAACTCAGG . . EXP=.;type=should not be called, can be normalized diff --git a/test/csq/ENST00000341065/splice-acceptor-donor7.txt b/test/csq/ENST00000341065/splice-acceptor-donor7.txt new file mode 100644 index 0000000..bff6673 --- /dev/null +++ b/test/csq/ENST00000341065/splice-acceptor-donor7.txt @@ -0,0 +1,3 @@ +18371 CAGG CAAAGG splice_region|SAMD11|ENST00000341065|protein_coding +18371 CAGG CAAAGG splice_region|SAMD11|ENST00000341065|protein_coding + diff --git a/test/csq/ENST00000341065/splice-acceptor-donor7.txt-l b/test/csq/ENST00000341065/splice-acceptor-donor7.txt-l new file mode 100644 index 0000000..bff6673 --- /dev/null +++ b/test/csq/ENST00000341065/splice-acceptor-donor7.txt-l @@ -0,0 +1,3 @@ +18371 CAGG CAAAGG splice_region|SAMD11|ENST00000341065|protein_coding +18371 CAGG CAAAGG splice_region|SAMD11|ENST00000341065|protein_coding + diff --git a/test/csq/ENST00000341065/splice-acceptor-donor7.vcf b/test/csq/ENST00000341065/splice-acceptor-donor7.vcf new file mode 100644 index 0000000..94a8707 --- /dev/null +++ b/test/csq/ENST00000341065/splice-acceptor-donor7.vcf @@ -0,0 +1,6 @@ +##fileformat=VCFv4.2 +##contig= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO +1 18371 . CAGG CAAAGG . . EXP=splice_region|SAMD11|ENST00000341065|protein_coding;type=same as 16261 but an insertion diff --git a/test/csq/ENST00000341065/splice-acceptor-donor8.txt b/test/csq/ENST00000341065/splice-acceptor-donor8.txt new file mode 100644 index 0000000..6ee8c26 --- /dev/null +++ b/test/csq/ENST00000341065/splice-acceptor-donor8.txt @@ -0,0 +1,3 @@ +18498 GGT GGTA splice_region|SAMD11|ENST00000341065|protein_coding +18498 GGT GGTA splice_region|SAMD11|ENST00000341065|protein_coding + diff --git a/test/csq/ENST00000341065/splice-acceptor-donor8.txt-l b/test/csq/ENST00000341065/splice-acceptor-donor8.txt-l new file mode 100644 index 0000000..6ee8c26 --- /dev/null +++ b/test/csq/ENST00000341065/splice-acceptor-donor8.txt-l @@ -0,0 +1,3 @@ +18498 GGT GGTA splice_region|SAMD11|ENST00000341065|protein_coding +18498 GGT GGTA splice_region|SAMD11|ENST00000341065|protein_coding + diff --git a/test/csq/ENST00000341065/splice-acceptor-donor8.vcf b/test/csq/ENST00000341065/splice-acceptor-donor8.vcf new file mode 100644 index 0000000..4a144be --- /dev/null +++ b/test/csq/ENST00000341065/splice-acceptor-donor8.vcf @@ -0,0 +1,6 @@ +##fileformat=VCFv4.2 +##contig= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO +1 18498 . GGT GGTA . . EXP=splice_region|SAMD11|ENST00000341065|protein_coding;type=splice region but not donor diff --git a/test/csq/ENST00000341065/splice-acceptor-donor9.txt b/test/csq/ENST00000341065/splice-acceptor-donor9.txt new file mode 100644 index 0000000..d295897 --- /dev/null +++ b/test/csq/ENST00000341065/splice-acceptor-donor9.txt @@ -0,0 +1,3 @@ +18498 GGTAAGGGG GGTAAGGGGA . +18498 GGTAAGGGG GGTAAGGGGA . + diff --git a/test/csq/ENST00000341065/splice-acceptor-donor9.txt-l b/test/csq/ENST00000341065/splice-acceptor-donor9.txt-l new file mode 100644 index 0000000..d295897 --- /dev/null +++ b/test/csq/ENST00000341065/splice-acceptor-donor9.txt-l @@ -0,0 +1,3 @@ +18498 GGTAAGGGG GGTAAGGGGA . +18498 GGTAAGGGG GGTAAGGGGA . + diff --git a/test/csq/ENST00000341065/splice-acceptor-donor9.vcf b/test/csq/ENST00000341065/splice-acceptor-donor9.vcf new file mode 100644 index 0000000..3109316 --- /dev/null +++ b/test/csq/ENST00000341065/splice-acceptor-donor9.vcf @@ -0,0 +1,6 @@ +##fileformat=VCFv4.2 +##contig= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO +1 18498 . GGTAAGGGG GGTAAGGGGA . . EXP=.;type=no consequence diff --git a/test/csq/ENST00000357367/ENST00000357367.fa b/test/csq/ENST00000357367/ENST00000357367.fa new file mode 100644 index 0000000..f4441d1 --- /dev/null +++ b/test/csq/ENST00000357367/ENST00000357367.fa @@ -0,0 +1,71 @@ +>1 1:13386626-13390785 +TTACGGAGGACACCAGATAGTTTCCACTCAGTTTCCCTTTATTTCTGACTGTTACTTTAC +AACCATCTGTGCAGGGGTAACCCTCTCATGTGTCTCTCCTCCCTGATTCTCACTCTAGCA +ATTCAGATTCCCATTTCTGATTCTCTGGGACACAGGTCTCTAAAGAGCCCATCCACTCCA +AGTCAACTTTTCCCCCAGTCCTGCCCCTCCTGCATCCTCATTCCTTTCCCATTCACACTG +AGGAGGCATTTGAAACGATGGGTCTGTGCTCCCTTTAACATGCACTCATGGCCTAGGTTT +CAGCTCCGAAATGACCAGAAGAAAGCTTGAAATATATCCACCCTGATGGCAGGCATTCAA +CAGAGGCAGTGACTGGGCTCCAGGTCATAGGAGGCCCTGATGCCACAGCGAGGGCAGGGG +ACGGTGCAGAACACAATGATCTTGGGCTGCCTTAAGTCCCTCAGTGTCTTCATCAGCTCA +GCCCCAAGTTCAGCAAATCTCCCCCAGCAGAGAGCACCCTGGGTGTCATAACTCTCCAGA +GGGGCAGGATACAGCTCCAGGCTTAGCTTGCTCAGCCCGACGGTGTGGCGCAGCAGGTTC +TCAAGGGCAGCCATGGAGATGAGGTTCCCACAGAAGCTGAAGGTGCTGAGCTGGGAGCAG +CGGCTCAGGACAGGCAGGATGGCGCTGAGTTGGGAATCCATGATCCCACAGTCCTCTAAG +TCCAGGGTCTGCAGGGTGGCCACAACTTGCTCCAGCAGACCTGTGAGGGGCTCAGGGCTG +AAATGGGTCAGTGTGACACCCCTCAGGTCCAGCTCCTTTAATTGACGGATGCTCGGGCAC +CAAGAGAGATGCTTCAAGTCCGACTCTGACAGCAGGCAGTCGGTCATAACGACCATCTCC +AAGGAGGCCTGGAGACACCTGGGAGAGAACAAGAAGTAGTTAGAGGAGAGAGGTGGGGAT +GACTTCAGGGTGAGAGATGATGCTCTCCATAACCCAGGGCTGCTCTGCTCATCTGAGGAT +AGTCAGCACCTGGGGTGTGGGAATGGAGACTCTGTTCCTTCAGTGCAGTCCCAATCGAGG +CTCAGTCCTTCACCATCACCGAGGTGATTGGATCAAGTCCATGAACTCTAAGTCTCCCTT +TCCTCATCTGTCAGGTAGAAAACCGCATCTCTGGGCCACAGGAGCCCGATGGAGACACAG +GCATAAATGACAAACCCAGGCAGGATCCTGCAACATCAGCTGGGTTGGCCAGGTTGCAGG +GGACCCTGACATGCCTGTACCATCAGCAAACCATCTATCACTTTTACCATTCTTTGCTCC +TGCTCCCTCACCCTCTATTCTATCATCATGTATTTCCCATACATTAATTACCTGACCTGG +AGCTCAAAACAGGGTGCTGACAGGGAAACATAGGATTTTGCCTGTTCACTAGGCAGGTGA +GGATAGACCTCATATTTTAAAATATAGGAGTGGGATGGGCATTCTCTTTAGTGCCCTCTT +CACCTCCCTATTTCCCATCATCTTAACTTAGACACACATCCTCAGGAGGAATTCACAAAT +GCACTCTCGCCAGATCTAAACCCTGCAGTAGCTAGCTTCCTAGCTTGGCACCTTCTCTAT +AGCATCTAGCCCAGGAGATCCCTCTGACTTTATTGGGATGGTTGTGTGATACCCGTATCA +GGACAGAGCCACCAACAGGATAATGCATGGATATTCTAGTGTCCCCTCACTCTTACTTCC +TCACAGGCTCACAGTGCATACCCACTGGTGTTTACTGTAACAAAGAAAGGCTCTGCTGTG +GTCTGAAGAGAAAGCTCACCATCCTTCCTCACCTGAGCAGCTGGTCCAGGTGGCCTTCGA +GGAAAGAGACGGAGTGCATAGACAGATTCTGGAAATAGTCCAGCTTGAGGAACTGAGAGG +TGAATCGGGCAATGAACTGCCCCTTGTTGTCTGGGGGAATGCAGGCAGATGCACGGATGT +TGAAGAGAACAAGTTTGCGGAGATTCCTCATCTGGCCCAGGTAAGGGGCAAACTTCACAA +GAGTGGACAGCTCCCAGGGGCAGCACACTTCCACCTCCTGGATACAGTCAAGCTCCACCA +TGTTCAGGACCTCTATGATACTGTGGATGGGCATTCCAAAAACCTGCAGCTCCTGGCAAC +ACACATGCAGTAAGCCTTTTCTCTGCTTGCCCCACTCTAAGAGGTGGGTGAGGCATTCAT +CTAGTGTCCTGTTCTTGAGACAAAGGTCTATGAACACCATGAATGGCTGCTGCCTGCCTG +TCCCTGGACAGTTATCTGCTGTTTGCTTCTGACTCAGAGCCTCCGGGAAGGATGCAGTAG +CTCCAGAAAATATGTCGCAGAAGTTCTCATCCACATTCCTCAAGTCCAGCACTTGAAGTT +TTGACTGCCTGTGGGTAAAGGAGAAGAGAGGCTCCAAACTAAGGCAAGGACCTGAGCTTT +TATTTACATCCCAGACATCAGCTGTTCTCCTCTCTGCCACTTTTCCCTCTCTGATTTTGT +CCAACCCCTTTTCCCTCCGGATTTTGCCTCATCCCCATTGCCTGTAGCTTTCAGAGCCAC +TAGAAGAGAAGTTTCTGTTTCCTCAGTGGACCCTGCATGGTGAGCAGTCCTTTCCCAGAG +GGGCTGGGCAATGGCCAAGGCCTTCCTGAGCTTCCTCACTGGCACCATCAGAAACCTCTG +GGCCTCCATGGTGCCCCTCCTCCTCCTGAAACAGCTGTCCCTACCCTGGACAAAAGGGCC +CTCCCCACCTGGACACCTGGGTCACCTCACCTGGGGCGAACCTCTTGGGTCAACAGCACA +TCAACCCCTTCCAGCACAGATTTTAATGACTCCAGATGAGGCGACTTCATCAGGGACCCT +AGAGGGAGGCGGGTGAAAGGCCAGGCCTGCACCATTGTTTTCAGGGTTTCACAGCGTCTC +CTGCTGAAGGCCTCCATGAACAGTGTGGGGAAGAGCTCCCTGGGCAGCTCCTCCATGGTG +GAGATGGCCAAGGCCTGGTCCCTCAGCAGCCTCTGCCTTGCCAGCTCCAGGAGTCTGGGT +GGGGCCCTGATGCTCATCTTGATGAATCTGCAAGGGAAAACTCTAGAGGACAAATCCAGA +GAAAAGGCATCACTCTCAGGCCAAATATGATCACCTCATCTTCTCCTATTGCTAATCTCA +TTGCTCTGGTGGAGGTGGAAAAGCCCTCAATTCCCCCCAGTTCCATTCTGCACTTGGTGG +CCACAAATCTGTATCTGTGCCCCTGTGACTACCACAAAGAATGTCTTCCAAACACCAAGG +AGGGGACGAGGTGGCCAGTGGCCCATTAATTTCTATACATTGCTCCACTGAAACTCAGGA +TTACTGGGATCTGTCACTCAGGATCCTGAAAGCTAAGCTCCACCTTTTTGAGGGAAATTT +TTTTGTTACTTACCACCCAAAAACAATGAGAATGACTGTCCTGTGGCCCCACACAGCCTG +CATTCTCAGTTTACACAATTAGCATGCTTGGGGAAGACTGAAGTGACTCCTTAAAATCAA +TGCCACTTGTTTTTATTTTGAAAAATTATAAGAGAAACTCTAAAAGCAGTGTGGCAGTAT +TCTAGAGCACTTGGAAGGTGCGGGTGGAAACACTAAGTCTCAGATGAAGGATCCAATACT +CATCCCTTCTACATACTCACAATCACCCACTTAGGGACAGAGTCTAAGGGCAGAGATAAA +TCCCATGTTCAGAACAAGACTCGAGAAAATCACAATACAACTAAGTGTGTGAACTGTAGC +TGAAGGGCACAGAAACAAAGAACTTCACATGTCAAGACATAAAAATTCATCCAACTGTAA +ATTTTTAATATCTTTTTTAAAAAACTGCTTCAATAAGAATTTTGAAATGAGAAAAATGAA +GCAGAAATCAAAATCTGAGGGATGAAGTGAATACTATATTTAGAGGAAAAATCAAAACCT +ACATCTGTTAAATTGAAAAAACAGACAGGAAATTCTCTGTGCCACTTTGGGCTGTGTGTC +ACCATCCCTGACTGGCTGGCTGCAGATCAGATGGGCGTGTTCCTAAGGAGGTGGTGACTT +ACCAGATCTGGACTCAGTTTGTAGGGTGCTGGGATCTCTCAGAGAATCAAGCAGTAGTTC +CAGGCACCAGGGCTTTGGGT diff --git a/test/csq/ENST00000357367/ENST00000357367.fa.fai b/test/csq/ENST00000357367/ENST00000357367.fa.fai new file mode 100644 index 0000000..d3dbe21 --- /dev/null +++ b/test/csq/ENST00000357367/ENST00000357367.fa.fai @@ -0,0 +1 @@ +1 4160 23 60 61 diff --git a/test/csq/ENST00000357367/ENST00000357367.gff b/test/csq/ENST00000357367/ENST00000357367.gff new file mode 100644 index 0000000..d1f2af8 --- /dev/null +++ b/test/csq/ENST00000357367/ENST00000357367.gff @@ -0,0 +1,12 @@ +1 ensembl_havana gene 21 4140 . - . ID=gene:ENSG00000182330;Name=PRAMEF8;biotype=protein_coding;description=PRAME family member 8 [Source:HGNC Symbol%3BAcc:24074];gene_id=ENSG00000182330;logic_name=ensembl_havana_gene;version=6 +1 ensembl_havana transcript 21 4140 . - . ID=transcript:ENST00000357367;Parent=gene:ENSG00000182330;Name=PRAMEF8-001;biotype=protein_coding;ccdsid=CCDS30597.1;havana_transcript=OTTHUMT00000022043;havana_version=1;tag=basic;transcript_id=ENST00000357367;version=2 +1 ensembl_havana three_prime_UTR 21 356 . - . Parent=transcript:ENST00000357367 +1 ensembl_havana exon 21 918 . - . Parent=transcript:ENST00000357367;Name=ENSE00001763203;constitutive=1;ensembl_end_phase=-1;ensembl_phase=2;exon_id=ENSE00001763203;rank=4;version=1 +1 ensembl_havana CDS 357 918 . - 1 ID=CDS:ENSP00000349931;Parent=transcript:ENST00000357367;protein_id=ENSP00000349931 +1 ensembl_havana exon 1833 2408 . - . Parent=transcript:ENST00000357367;Name=ENSE00001787203;constitutive=1;ensembl_end_phase=2;ensembl_phase=2;exon_id=ENSE00001787203;rank=3;version=1 +1 ensembl_havana CDS 1833 2408 . - 1 ID=CDS:ENSP00000349931;Parent=transcript:ENST00000357367;protein_id=ENSP00000349931 +1 ensembl_havana CDS 2791 3077 . - 0 ID=CDS:ENSP00000349931;Parent=transcript:ENST00000357367;protein_id=ENSP00000349931 +1 ensembl_havana exon 2791 3102 . - . Parent=transcript:ENST00000357367;Name=ENSE00001764121;constitutive=1;ensembl_end_phase=2;ensembl_phase=-1;exon_id=ENSE00001764121;rank=2;version=1 +1 ensembl_havana five_prime_UTR 3078 3102 . - . Parent=transcript:ENST00000357367 +1 ensembl_havana exon 4083 4140 . - . Parent=transcript:ENST00000357367;Name=ENSE00001633251;constitutive=1;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001633251;rank=1;version=1 +1 ensembl_havana five_prime_UTR 4083 4140 . - . Parent=transcript:ENST00000357367 diff --git a/test/csq/ENST00000357367/stop-retained.txt b/test/csq/ENST00000357367/stop-retained.txt new file mode 100644 index 0000000..234c013 --- /dev/null +++ b/test/csq/ENST00000357367/stop-retained.txt @@ -0,0 +1,3 @@ +358 C T stop_retained|PRAMEF8|ENST00000357367|protein_coding|-|475*|358C>T +358 C T stop_retained|PRAMEF8|ENST00000357367|protein_coding|-|475*|358C>T + diff --git a/test/csq/ENST00000357367/stop-retained.vcf b/test/csq/ENST00000357367/stop-retained.vcf new file mode 100644 index 0000000..465df30 --- /dev/null +++ b/test/csq/ENST00000357367/stop-retained.vcf @@ -0,0 +1,7 @@ +##fileformat=VCFv4.2 +##contig= +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO +1 358 . C T . . EXP=stop_retained|PRAMEF8|ENST00000357367|protein_coding|-|475*|358C>T;type=ENST00000357367:13386983-C-T diff --git a/test/csq/ENST00000368801/ENST00000368801.fa b/test/csq/ENST00000368801/ENST00000368801.fa new file mode 100644 index 0000000..78182f7 --- /dev/null +++ b/test/csq/ENST00000368801/ENST00000368801.fa @@ -0,0 +1,204 @@ +>1 1:152184538-152196689 +TGAGAAAAGTCTTAGTATTTAATCAACATTTATTTATTGTCAATTTTAATACAATCCGGT +TGTTTGAATCCAAAGACTTGAAACAAATGTGTTACAGTCAAATTAAGGAACTATGTAGCA +GTGACAGATACTCTTCCTTTTCATCTGGGCATGGATGATATTTTTTCAGGTGGAAACGTT +ATTGAACTACAGTAGTAGGTGGAAAGCATTGTATTTCCATGGAATAACTCCTCAATATAT +TTCCCAATATTGAGCAGCCTCTTAGAAATAGGGAGCAAGATCTTTCTGCTGAAAACAAGC +TAAAGCCCACATTTGAATGTTTTTTTTTTTCCTGAAATGATAAATCCCTATTCTTTATGA +AATAATGCTCTTGCTCACTGGCTTGGGAAAAGACCCTGATGCTACTTTTTTATGCCACTA +ATTAACTTACTGATTAAATATATACCCAAGAAAAAGGACTTGATGGTTTTGATAAGTAAA +GACACTACCGCTGCTGCATCTTTGCTTTCAGAGCCTTCACCTTCTGCCACAATACCAAAA +ATTGGGACACACCAAACTTGGGGCACACTAAAAATTAGGGTACACTAATTGCTGTAAAAC +AAAGCTTTGTATCTAGGACTGGTAATGCATTTGTAATATTTTGCTTCTAAGAAATGTAAG +GTTAGCTTTGGCACCATCTATAAATGAATGATGAGCTCTCAAAAAGACAACTCCAACTAA +ACCCAAAGCTCTTTAAAAGCTTTTCATTATTCCTCAAAGTTTAACCCTCATTCTAACAAG +TTATTCCACTCAGTATTTTCTAACAAAGTAGCACAAATGCCTAACAGTCTTTGGAAGGAA +CCCCATAACAAGATATATGCTACAGTTTTAGGCTCTAAAGAAAGAGACAGAAATGCATTG +ATTCACTTTTAGAACGAATTTCATGATGGATTGCTTGTCTTTCATGATGAATTCATAGAT +GACTTTCCTATTTCTTAAATTGCTACTTGAGTAAATTGCATTTATGTTTATTATTCACTG +ATAAAAGTAGCACCTCTGCTCTTGGACATATTCATAGGGTGAAGTGCTACTAGGAAAACT +GAGAAAATATGAGCCAGAACTTCCCCCATCATGGTTACTTCCTCCTTTGCAATAAGAATA +CCCATCTTGCCCTGAGCCACTTCCATGCTGACTATAACCAGAGGACTGTCCTGAGCCAGA +CCCATGTTGGCCGTAGCTGGAAGACTGCCCTGAACCAGACCCGTGTCGGCCGTGGCTAAG +AGACTGGCCAGATCCAGCCCCATGTCGGCCATAGCCAGAAGACTGACTGGAGCCAGAGCC +ACGGTGGCCATAGCTGGAAGACTGGCCTGTGCTAGATCCCTCCTGGTCAAAGGTTGATGA +CTGTCCTGATGTAGAACCATGCTGTCCTTGGCTACAGAAGTGCCCTGAGCCACTACCATG +CTGACTGTAAGCAGAGGAATGTCCTGAGCCAGACTCATGTTGACCAAAGACAGAAGAGTG +ACCCAAGCGAGACTCATATGGGCCACGGCTGGAAGAACGACCTGAGCCAGACCCATGTTG +GCCGTGGCTGGAGGAGTGCCCCAAACCGGACCCATGTCGGCCGCGGCTAGGGGACTGGCC +AGATCCAGACCCTTGTCGGCCGTGGCCCGAAGACTGACGGGAGCCAGACCCATGCTGACC +ATAGTGGGAAGACGAACCTGAGCTAGATCCGTGTCGTTCACCCCTAGATGACTGTCCTGA +TCTAGAGCCGTGTTGTCCGTAGCCAGAGGAGTGACCTGAGCCAGACCCATGCTGACTGTA +ACTAGAGGACTGCCCTGAGCTAGACTCGTGGTGACCAAAGCCAGAAGACTCGCCTAAGCC +AGACCCATGTTGGCCACTGCTGGAAGACCGACCGGAGCCAGACCCATGTCGGCCGTAGCT +GGGAGACTGCCTTGACCCAGACCCACGCTGGCCGTGGCCTGGAGACTGGCCAGATCCAGA +GCCCTGTCGGCCATAGCCAGAAGACTGACTTGAGCCAGAGCCATGCTGACCGTGGCTGGA +AGACTGACCTGAGCTAGCTCCATGTTGGCCACAGCTCGATGACTGTCCTGATGTAGAACC +ATGTTGCCCATGGGTAGAGGAATGACCTGAGCTAGATCCATGTTGACCGTAGCCAGAGGA +CTGTCCTGAGCGAGACTCTCGGTGACCTAAGCCAGAAGAGTGACCGGAGCCAGACTCATA +TGGGCCACGGCTGGAAGACCACCCTGAGCCAGACCCATATGGGCTGTAGCTGGAAGACTG +CCCAGAACCAGACCCATGTCGGCCACGGCTAGGGCTAGGAGACTGGCCAGATCCAGACCC +ATGTTGGCCGTGGCCCAAAGACTGACGGGAGCCAGACCCATGCTGACCATAGCTGGAAGA +TGAACCTGAGCTAGATCCGTGTCGTTCACCCCTAGATGACTGTCCTGACCTAGAGCCGTG +TTGTTCGTAGCTGGAGGAGTGACCTGAGCCAGATCCATGCTGAGTGTAACCAGAGGACTG +CCATGAGCTAGACTCGTGGTGACCAAATCCAGAAGACTGACCTGAGCCAGACCCATGTCG +GCCACTGCTGGAAGACCAACCGGAGCCAGACCCATGTTGGCCGTAGCTGGAAGAGTGCCC +GGAACCGGACCCATGTCGGCCGCGACTAGGAGACTGGCCAGATCCAGAGCCCTGTTGGCC +ATAGCTAGAAGACTGACTTGAGCCAGAGCCATGCTGACCGTGGCTGGAAGACTGACCTGT +GCTAGATCCCTCCTGGTCAAAGGTTGATGACTGTCCTGATGTAGAACCATGCTGTCCTTG +GCTACAGAAGTGCCCTGAGCCACTACCATGCTGACTGTAAGCAGAGGAATGTCCTGAGCC +AGACTCATGTTGACCAAAGACAGAAGAGTGACCCGAGCGAGACTCATATGGGCCACGGCT +GGAAGAACGACCTGAGCCAGACCCATGTTGGCCGTGGCTGGAGGAGTGCCCCGAACCGGA +CCCATGTCGGCCGCGGCTAGGGGAATGGCCAGATCCAGACCCTTGTCGGCCGTGGCCCGA +AGACTGACGGGAGCCAGACCCATGCTGACCATAGCGGGAAGACGAACCTGAGCTAGATCC +GTGTCGTTCACCCCTAGATGACTGTCCTGATCTAGAGCCGTGTTGTCCGTAGCCAGAGGA +GTGACCTGAGCCAGACCCATGCTGACTGTAACTAGAGGACTGCCCTGAGCTAGACTCGTG +GTGACCAAAGCCAGAAGACTCGCCTAAGCCAGGCCCATGTTGGCCACTGCTGGAAGACCG +ACCGGAGCCAGACCCATGTCGGCCATAGCTGGGAGACTGCCTTGACCCAGACCCACGCTG +GCCGTGGCCTGGAGACTGGCCAGATCCAGAGCCCTGTCGGCCATAGCCAGAAGACTGACT +TGAGCCAGAGCCATGCTGACCGTGGCTGGAAGACTGACCTGAGCTAGCTCCATGTTGGCC +ACAGCTCGATGACTGTCCTGATGCAGAACCATGTTGCCCATGGGTAGAGGAATGACCTGA +GCTAGATCCATGTTGACCGTAGCCAGAGGACTGTCCTGAGCGAGACTCTCGGTGACCTAA +GCCAGAAGAGTGACCGGAGCCAGACTCATATGGGCCACGGCTGGAAGACCACCCTGAGCC +AGACCCATATGGGCCGTAGCTGGAAGACTGCCCAGAACCAGACCCATGTCGGCCACGGCT +AGGGCTAGGAGACTGGCCAGATCCAGACCCATGTTGGCCGTGGCCCAAAGACTGACGGGA +GCCAGACCCATGCTGACCATAGCTGGAAGATGAACCTGAGCTAGATCCGTGTTGTTCACC +CCTAGATGACTGTCCTGACCTAGAGCCGTGTTGTTCGTAGCTGGAGGAGTGACCTGAGCC +AGATCCATGCTGAGTGTAACCAGAGGACTGCCATGAGCTAGACTCATGGTGACCAAATCC +AGAAGACTGACCTGAGCCAGACCCATGTCGGCCACTGCTGGAAGACCAACCGGAGCCAGA +CCCATGTTGGCCGTAGCTGGAAGAGTGCCCGGAACCGGACCCATGTCGGCCGCGACTAGG +AGACTGGCCAGATCCAGAGCCCTGTTGGCCATAGCTAGAAGACTGACTTGAGCCAGAGCC +ATGCTGACCGTGGCTGGAAGACTGACCTGTGCTAGATCCCTCCTGGTCAAAGGTTGATGA +CTGTCCTGATGTAGAACCATGCTGTCCTTGGCTACAGAAGTGCCCTGAGCCACTACCATG +CTGACTGTAAGCAGAGGAATGTCCTGAGCCAGACTCATGTTGACCAAAGACAGAAGAGTG +ACCCGAGCGAGACTCATATGGGCCACGGCTGGAAGAACGACCTGAGCCAGACCCATGTTG +GCCGTGGCTGGAGGAGTGCCCCAAACCGGACCCATGTCGGCCGCGGCTAGGGGACTGGCC +AGATCCAGACCCTTGTCGGCCGTGGCCCGAAGACTGACGGGAGCCAGACCCATGCTGACC +ATAGCGGGAAGACGAACGTGAGCTAGATCCGTGTCGTTCACCCCTAGATGACTGTCCTGA +TCTAGAGCCGTGTTGTCCGTAGCCAGAGGAGTGACCTGAGCCAGACCCATGCTGACTGTA +ACTAGAGGACTGCCCTGAGCTAGACTCGTGGTGACCAAAGCCAGAAGACTCGCCTAAGCC +AGACCCATGTTGGCCACTGCTGGAAGACCGACCGGAGCCAGACCCATGTCGGCCGTAGCT +GGGAGACTGCCTTGACCCAGACCCACGCTGGCCGTGGCCTGGAGACTGGCCAGATCCAGA +GCCCTGTCGGCCATAGCCAGAAGACTGACTTGAGCCAGAGCCATGCTGACCGTGGCTGGA +AGACTGACCTGAGCTAGCTCCATGTTGGCCACAGCTCGATGACTGTCCTGATGTAGAACC +ATGTTGCCCATGGGTAGAGGAATGACCTGAGCTAGATCCATGTTGACCGTAGCCAGAGGA +CTGTCCTGAGCGAGACTCTCGGTGACCTAAGCCAGAAGAGTGACTGGAGCCAGACTCATA +TGGGCCACGGCTGGAAGACCACCCTGAGCCAGACCCATATGGGCTGTAGCTGGAAGACTG +CCCAGAACCAGACCCATGTCGGCCACGGCTAGGGCTAGGAGACTGGCCAGATCCAGACCC +ATGTTGGCCGTGGCCCAAAGACTGACGGGAGCCAGACCCATGCTGACCATAGCTGGAAGA +TGAACCTGAGCTAGATCCGTGTCGTTCACCCCTAGATGACTGTCCTGACCTAGAGCCGTG +TTGTTCGTAGCTGGAGGAGTGACCTGAGCCAGATCCATGCTGAGTGCAACCAGAGGACTG +CCATGAGCTAGACTCGTGGTGACCAAATCCAGAAGACTGACCTGAGCCAGACCCATGTCG +GCCACTGCTGGAAGACCAACCGGAGCCAGACCCATGTTGGCCGTAGCTGGAAGAGTGCCC +AGAACCGGACCCATGTCGGCCGCGACTAGGAGACTGGCCAGATCCAGCCCCATGTCGGCC +ATAGCCAGAAGACTGACTGGAGCCAGAGCCACGGTGGCCATAGCTGGAAGACTGGCCTGT +GCTAGATCCCTCCTGGTCAAAGGTTGATGACTGTCCTGATGTAGAACCATGCTGTCCTTG +GCTACAGAAGTGCCCTGAGCCACTACCATGCTGACTGTAAGCAGAGGAATGTCCTGAGCC +AGACTCATGTTGACCAAAGACAGAAGAGTGACCCGAGCGAGACTCATATGGGCCACGGCT +GGAAGAACGACCTGAGCCAGACCCATGTTGGCCGTGGCTGGAGGAGTGCCCCAAACCGGA +CCCATGTCGGCCGCGGCTAGGGGAATGGCCAGATCCAGACCCTTGTCGGCCGTGGCCCGA +AGACTGACGGGAGCCAGACCCATGCTGACCATAGTGGGAAGACGAACCTGAGCTAGATCC +GTGTCGTTCACCCCTAGATGACTGTCCTGATCTAGAGCCGTGTTGTCCGTAGCCAGAGGA +GTGACCTGAGCCAGACCCATGCTGACTGTAACTAGAGGACTGCCCTGAGCTAGACTCGTG +GTGACCAAAGCCAGAAGACTCGCCTAAGCCAGACCCATGTTGGCCACTGCTGGAAGACCG +ACCGGAGCCAGACCCATGTCGGCCGTAGCTGGGAGACTGCCTTGACCCAGACCCACGCTG +GCCGTGGCCTGGAGACTGGCCAGATCCAGAGCCCTGTCGGCCATAGCCAGAAGACTGACT +TGAGCCAGAGCCATGCTGACCGTGGCTGGAAGACTGACCTGAGCTAGCTCCATGTTGGCC +ACAGCTCGATGACTGTCCTGATGTAGAACCGTGTTGCCCATGGGTAGAGGAATGACCTGA +GCTAGATCCATGTTGACCGTAGCCAGAGGACTGTCCTGAGCGAGACTCTCGGTGACCTAA +GCCAGAAGAGTGACCGGAGCCAGACTCATATGGGCCACGGCTTGAAGACCACCCTGAGCC +AGACCTATATGGGCCATAGCTGGAAGACTGCCCGGAACCAGACCCATGTCGGCCACGGCT +AGGGCTAGGAGACTGGCCAGATCCAGACCCATGTTGGCCGTGGCCCAAAGACTGACGGGA +GCCAGACCCATGCTGACCATAGCTGGAAGACGAACCTGAGCTAGATCCATGTTGTTCGCT +CCTAGATGACTGTCCTGACCTAGAGCCGTGTTGTTCGTAGCTGGAGGAGTGACCTGAGCC +AGATCCATGCTGAGTGTAACCAGAGGACTGCCCTGAGCTAGACTTGTGACCAAAGCCAGA +AGACTGGCCTGAGCCAGACCCATGTCGGCCACTGCTGGAAGACCGACCGGAGCCAGACCC +ATGTCGGCCATAGCTGGGAGACTGCCCTGACCCAGACCCACGCTGGCCGTGGCCTGGAGA +CTGGCCAGATCCAGAGCCATGTCGGCCGCGGCCCGAAGCGTGATGGGAGGCAGACTCATG +CTGACCATAGCTGGAAGATTGACCTGAGCTAGAGTCATGTTGGCCGGAGCTTGATGACTG +CCCTGACGTAGATCCATGTCGTCCCTGGCTAGAGAAGTGACCTGAGGCAGAACCATGCTG +ACTATAGCCCTGTCCTGAGCCAGACTCGTGTTGCCCAAAACCAGAAGCCTGGCCTGAGCC +AGACTCATAATGGCCACAGCTGGAAGAACAACTTGTGCCAGACCCGTGTTGGCCGTGGCT +GGAGGAGTGCCCTGAACTGGACCCATGTCGGACACGGCTAGGAGAGTGGCCAGATCCAGA +CCCTTGTCGGCCGTGGCCCGAAGATTGATGGGAGCCCGACCCATGCTGACCATAGCTGGA +AGACAAACCTGAGCTAGATCCGTGTTGTTCACTCCTAGATGACTGTCCTGACCTAGAGCC +GTGTTTTCTGTAGCCGGAGGAGTGACTTGAGCCAGATCCATGCTGACTGTAACCAGAGGA +CTGCCCTGAGCCAGACTTGTGACCAAAGCCGGAAGACTGGCCTGAGACAGACCCATGTGG +GCCATTGCTTGAAGACCAACCGGAGCCAGACCCATGTTGGCCGTAGCTGGAAGAGTGCCC +AAAATCGGACCCATGTCGGCCGCGACTAGGAGACTGGCCAGATCCAGAGCCCTGTTGGCC +ATAGCGAGAAGACTGACTTGAGCCAGAGCCATGCTGACCGTGGCTGGAAGACTGACCTGA +GGTAGCTCCATGTTGGCCACAGCTCGATGACTGTCCTGATGTAGAACCATGTTGCCCATG +GGTAGAGGAATGACCCGAGCTAGATCCGTGTTGACCGTAGCCAGAGGACTGTCCTGAGCG +AGACTCTTGGTGACCTAAGCCAGAAGAGTGACCGGAGCCAGACTCATATGGGCCACGGCT +TGAAGACCTCCCTGAGCCATACCCATGTGGGCCATAGCTGGAAGACTGCCTGGAACCAGA +CTCATGTCGGCCACGGCTAGGGCTAGGAGACTGGCCAGATCCAGACCCATGTCGGCTGTG +TCCCAAAGATTGACGGGAGCCAGACCCATGCTGACCATAGCTGGAAGATGAACCTGCACT +AGATCCTTGTCGTTCACCCCTAGATGACTGTCCTGACCTAGAGCCGTGTTGTCCGTGGCC +GGAGGAGTGACCTGAGCCAGATCCATGCTGAGTGTAACCAGAGGAATGCTCTGAGCTAGA +CTCGTGGTGACCAAAGCCAGAAGAGTAGCCTGAACCAGACACATATGGGCCACTGCTGGA +AGATCGACCAAAGCCAGTCCCATGTTGGCCGGAGCTGGGAGACTGCCCTGACCCAGACCC +ACGCTGGCCGTGGCCTGGAGACTGGCCAGATCCAGAGCTGTGTTGGCCGCGGCCTGAAGA +GTGACGGGAGGCAGACTCATGCTGACCATAGCTGGAAGACTGACGTGAGCTGGAGCCATG +TTGGCCAGAGCTTGATGCCTGCCCTGACGTAGATCCATGTTGTCCCTGGCTAGAGGAGTG +ACCTGAGCCAGAACCATGCTTACTATAGCCAGAGGACTGTCCTGAGCCAGACTCATGTTG +CCCAAAGCCAGAAGTCTGGCCTGAGCCAGACTCATAATGGCCACGGCTGTAAGAGTAACT +TGAGCCAGACCCGTGTTGGCCGTGGCTGGAGGAGTGCCCCGAACCGGACCCATGTCGGAC +GTGGCTAGGAGACTGGCGAGATCCAGACCCTTGTCGGCCGTGGCCCAAAGACTGACGGGA +ACCAGACCCATGCTGACCATAGCTGGAAGACGAACCTGAGCTAGATCTGTGTCGTTCACC +CCTAGATGACTGTCCTGACCTAGAGCCGTGTTGTCCGTAGCCAGAGGAGTGACCTGAGCC +AGATCCATGCTGACTGTAACCAGAGGACTGCCCTGAGCTAGACTTGTGTTGACTAAAGCC +AGAAGACTGGCCTGAGCCAGACCCATGTGTGTCATTGCTGGAAGACTGTCCGGAGCCAGA +GCCGTGTTGGCCATAGTTGGGAGACTGCCCTGACCCAGACCCACATTGGCCGCGGCCTGA +AGACTGATGGGAGTCGGAGTTTTGCTCACCATAGCTGGAAGACTGACCTGAGTAGGAGTT +ATGTTGGCCAGAAAAGTCTCTTTGAAAACTCAGTCTTCTGGATATGGATTCAGTCCCAGG +TTTAAGACTTCCTCTGACGTTTCTGGAATAGGAATCATTCTCTCCTGCACTCCAACTTGA +ATGACTAAAAGAGGATTCTTGCCGTTTGTTCTCCTCTTTTTCAGTTTCTTCTTGTTCCTC +TTGGTGCTGGTGAGTGTCATCTCTCAGCTTTGACCCTGAAACTTGGCAGTAATCTTTGCC +AATGATTTTATTACGAGCCTGAACCAGCTTGAATATCATCAGAAGATACTCAGTAAAATC +CACTTTCTTGTTATGGTCTCGATCCAGACTTTGCAAGATGATATCCACAGTATCTGGATC +GTTTGGATTCTGTATAAGAGAAAGGTACAAAGAGTAGCTCTGTTAGTATGGACAATACAT +CTGGCTAACGAACTGAAGGAAAGATGTGAAAATGTAAATGTTTGGGTTATTTATATGGAA +CTCATTCACACAGTCCTTTAGGCTGCATTTCTGTATCCTGAGCAGAAAGAGAAAAAGGAA +TATGGAATGAATAATGTGGTGGGAAACAGCTAGAATAGGATGCAACTGGAAGATGAAAGG +AAACAAGAGGGCTGATTATTTTTGGTAAAGAATGGGTCAAATATGAATGATTAGCTAATT +TATAAGTAATATGTTTTTATACCTACATTAATTATATCAACTTTATTTATCCAATTAAAT +TAACTAGCTACTTAATTTACTCACTGAACAAAGATTTATTATTTTACTAGTTGCCTACCA +TTATGTCATATGAGAGTATAAAGAAGTGAACAAGTTTGCTTCCTGAAAAAAAATGGAATT +TAAAGTTTAGTTGGCCAGATATACAAACTTAAAATTATAATTTATTGTGGTAAGGTTTCT +ACAAGAGTACATCAGAGAGGAAACATTGGGGGTCCTAGAAAGGTTAATGAGAGGAAATGA +TGCCTTTTGAAGGATGGATTAGGATTAGCCAAATGAAGAAGTAGGAAGAGAAAGAGAAGG +GGAAAAGATTGTTCTAGGCAGAGGGAATTATATGAACAAAGGGCTAGAGGTGAGAGAAGT +TATGGAGCATTCAAGGAACTGAAGGAAATTCAGGATTGCTAGATTTAGAGTTTGAAGAGT +CAAGAAATGTGGATAGAGAGACAAATAGGGACTAGATTATGACTTTTAAGTTATGTTAAG +GAACTTTGTACTTCATTTTAAGAGCAATTGGGAACTATTGAAGGATTTTTAGCTGAGGAG +TGAAATGATTATATTTGCATCCAATGCTGAGAGTAGAAGTAGTAGGTGGCCTGAACCAGA +GGACTAATAATAGTGATGAAGAGAAATGGGTTGTTTTGAGAGATTATTGATGAGTTAGAT +GGAGGTTAGAAGGTAGTGGTGTCTGCTGAGAGAGAGACAATAAAAAATGACACCAGGTTT +TTGCTTTGGGCAAAAAGATGAAGGAAAAAGGTTAGTGGGGAAGATTATGAGATTCATAGC +TGACACACTGAATATCTGACATCTGATATCTGAATATCATATCTGAAATCCACAGAAATC +CAAATTTAAGGAATTGAAACTCAGGAGTCTGATATAAGGTCCCAAATATCTAAGCTATCA +AATCTAGACCTGACAGTTTTAAGGTGGTGGACACATTCTTTTGTGATTCAGGAGTAAATG +CCAATTTCCTGAACTCAGAAATCTACTTCACAGTTTTTCTGAGGACTGTCTGGGTTTGTA +GGAATTAGTCACTTAGATAGGACATTATTTAACCTGTGGGTTTTGTTTGTTGTTTAGTAA +GGTCACTTCCGTTAGTTATGCTATGGAAACCATCACGGATCTGCTTTTGACCTTATCTCA +AACTTTTACCAAACCCTGTTCTCTCTCACCAAGTAAGGACAATCCTCTAGGATGTTTGAC +ATATGTGACAAGAAGGTGGAAAGGGATAAAGAAGAAAATTCCTGCATAACTCCATCCTGG +CGTGGAGTTCTTACCTTCAGAATTTGATGAAACTCATTTTCCAGAAGTTCTTTCAGCTCT +GCCTTGTTCAACGTATCATACTCCCCATGCTGGGTGGCATATTGGTAGAAAACATCGATG +ACAGTGATGACGCCTTGTAGGAGTTTAGGCATTTTTTTTTTTGCAAGTTTGAGTAACCTA +AAGGGAGGAAAAAGAGAGACCAACCCCTTACTATTCTTATTTCTTGTTTAAACACATAAA +TAGTTCTAATTATTTATAATAATTGTTCAGAATTAGTCAGTCATGATTAAATTCATTCTG +TTGTAATCAAGAACCAATTCAGAGTTGAATGACTTGTTCAAGCCATGTAGCAAGAGAGTG +ATGAAATTAGGAATATAATCCATAGGTCTTATTTCCATTCCTGAATGAATGTAGGAAAAA +TGACTTTCTGTTTTTGGCTTCCTGCCATTACCAGGGATAATATTAGCTTTGTTCTGGAGC +TGTAGAAGTCCTGAGTGTTCCACTTCATCTGCTTCCTCTTTCTAGGTTCGAAGCATACTG +TGGGCATAGGTCCATCATCTACATGACATGCCTTACTCAACCTAAGGAGCATCAATGGCT +GAACTGAACTCTCAAGACTTCTAGGTCAGAGAAAATAGACAATGTGAGCAAAGCCAACAA +GCCTAGGTGATATGAAGCTAAGGGTAACTGCTATTAGATCCAGCTTCTGTTCTCATTCTC +CAAGCAGGAAGTGACCCTCAGACCTTATTACACAATAGAGAGGAAAAGCTCAGTTGTAAA +GAAGGCAACCTGCCTGTGGATAATTAGAACCCCATGATATCCATGTTATAAGGGAAGCGA +CCTCAAAGAAAGGAGATAATATACATAGTCCTAGTCTTTGTTTCATTTTTCTTTTCAGTA +AATTTAAACTTATACCAAAGTTCCCCAGAGTATACTAAAAAGAAGCCTTGTATCTAGTGC +CTCTTTGCCTTAGAGCACATCCTGGACTTTCATAATTTATAGCCCTAAGTACCCTTGAGC +GGAGTTGAACTGCTCACTTACCTAGCTCACCAGAGGAACAAGTAGGGTAGAGACAGAAAC +AGCTTTCAGGGTGCTGCGAGTTGGGCAGAGTG diff --git a/test/csq/ENST00000368801/ENST00000368801.fa.fai b/test/csq/ENST00000368801/ENST00000368801.fa.fai new file mode 100644 index 0000000..199029f --- /dev/null +++ b/test/csq/ENST00000368801/ENST00000368801.fa.fai @@ -0,0 +1 @@ +1 12152 25 60 61 diff --git a/test/csq/ENST00000368801/ENST00000368801.gff b/test/csq/ENST00000368801/ENST00000368801.gff new file mode 100644 index 0000000..30b389a --- /dev/null +++ b/test/csq/ENST00000368801/ENST00000368801.gff @@ -0,0 +1,10 @@ +1 ensembl_havana gene 21 12132 . - . ID=gene:ENSG00000197915;Name=HRNR;biotype=protein_coding;description=hornerin [Source:HGNC Symbol%3BAcc:20846];gene_id=ENSG00000197915;logic_name=ensembl_havana_gene;version=5 +1 ensembl_havana transcript 21 12132 . - . ID=transcript:ENST00000368801;Parent=gene:ENSG00000197915;Name=HRNR-001;biotype=protein_coding;ccdsid=CCDS30859.1;havana_transcript=OTTHUMT00000034016;havana_version=1;tag=basic;transcript_id=ENST00000368801;version=2 +1 ensembl_havana three_prime_UTR 21 1014 . - . Parent=transcript:ENST00000368801 +1 ensembl_havana exon 21 9429 . - . Parent=transcript:ENST00000368801;Name=ENSE00001447986;constitutive=1;ensembl_end_phase=-1;ensembl_phase=0;exon_id=ENSE00001447986;rank=3;version=2 +1 ensembl_havana CDS 1015 9429 . - 0 ID=CDS:ENSP00000357791;Parent=transcript:ENST00000368801;protein_id=ENSP00000357791 +1 ensembl_havana CDS 11055 11192 . - 0 ID=CDS:ENSP00000357791;Parent=transcript:ENST00000368801;protein_id=ENSP00000357791 +1 ensembl_havana exon 11055 11217 . - . Parent=transcript:ENST00000368801;Name=ENSE00001447987;constitutive=1;ensembl_end_phase=0;ensembl_phase=-1;exon_id=ENSE00001447987;rank=2;version=1 +1 ensembl_havana five_prime_UTR 11193 11217 . - . Parent=transcript:ENST00000368801 +1 ensembl_havana exon 12082 12132 . - . Parent=transcript:ENST00000368801;Name=ENSE00001447988;constitutive=1;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001447988;rank=1;version=2 +1 ensembl_havana five_prime_UTR 12082 12132 . - . Parent=transcript:ENST00000368801 diff --git a/test/csq/ENST00000368801/compound-lost.txt b/test/csq/ENST00000368801/compound-lost.txt new file mode 100644 index 0000000..792deff --- /dev/null +++ b/test/csq/ENST00000368801/compound-lost.txt @@ -0,0 +1,9 @@ +4310 A G @11191 +4310 A G @11191 + +6298 G A @11191 +6298 G A @11191 + +11191 AT A frameshift&start_lost|HRNR|ENST00000368801|protein_coding|-|1MPKLLQGVITVIDVFYQYATQHGEYDTLNKAELKELLENEFHQILKNPNDPDTVDIILQSLDRDHNKKVDFTEYLLMIFKLVQARNKIIGKDYCQVSGSKLRDDTHQHQEEQEETEKEENKRQESSFSHSSWSAGENDSYSRNVRGSLKPGTESISRRLSFQRDFSGQHNSYSGQSSSYGEQNSDSHQSSGRGQCGSGSGQSPNYGQHGSGSGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSLSHGRHGSGSGQSSSYGQHGSGSGQSSGYSQHGSGSGQDGYSYCKGGSNHDGGSSGSYFLSFPSSTSPYEYVQEQRCYFYQ*>1CLNSYKASSLSSMFSTNMPPSMGSMIR*|4310A>G+6298G>A+11191AT>A +11191 AT A frameshift&start_lost|HRNR|ENST00000368801|protein_coding|-|1MPKLLQGVITVIDVFYQYATQHGEYDTLNKAELKELLENEFHQILKNPNDPDTVDIILQSLDRDHNKKVDFTEYLLMIFKLVQARNKIIGKDYCQVSGSKLRDDTHQHQEEQEETEKEENKRQESSFSHSSWSAGENDSYSRNVRGSLKPGTESISRRLSFQRDFSGQHNSYSGQSSSYGEQNSDSHQSSGRGQCGSGSGQSPNYGQHGSGSGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSLSHGRHGSGSGQSSSYGQHGSGSGQSSGYSQHGSGSGQDGYSYCKGGSNHDGGSSGSYFLSFPSSTSPYEYVQEQRCYFYQ*>1CLNSYKASSLSSMFSTNMPPSMGSMIR*|4310A>G+6298G>A+11191AT>A + diff --git a/test/csq/ENST00000368801/compound-lost.vcf b/test/csq/ENST00000368801/compound-lost.vcf new file mode 100644 index 0000000..4ba1457 --- /dev/null +++ b/test/csq/ENST00000368801/compound-lost.vcf @@ -0,0 +1,9 @@ +##fileformat=VCFv4.2 +##contig= +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO +1 4310 . A G . . EXP=@11191;type=ENST00000368801:152188847-A-G +1 6298 . G A . . EXP=@11191;type=ENST00000368801:152190835-G-A +1 11191 . AT A . . EXP=frameshift&start_lost|HRNR|ENST00000368801|protein_coding|-|1MPKLLQGVITVIDVFYQYATQHGEYDTLNKAELKELLENEFHQILKNPNDPDTVDIILQSLDRDHNKKVDFTEYLLMIFKLVQARNKIIGKDYCQVSGSKLRDDTHQHQEEQEETEKEENKRQESSFSHSSWSAGENDSYSRNVRGSLKPGTESISRRLSFQRDFSGQHNSYSGQSSSYGEQNSDSHQSSGRGQCGSGSGQSPNYGQHGSGSGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSLSHGRHGSGSGQSSSYGQHGSGSGQSSGYSQHGSGSGQDGYSYCKGGSNHDGGSSGSYFLSFPSSTSPYEYVQEQRCYFYQ*>1CLNSYKASSLSSMFSTNMPPSMGSMIR*|4310A>G+6298G>A+11191AT>A;type=ENST00000368801:152195728-AT-A diff --git a/test/csq/ENST00000373833/ENST00000373833.fa b/test/csq/ENST00000373833/ENST00000373833.fa new file mode 100644 index 0000000..9a3d253 --- /dev/null +++ b/test/csq/ENST00000373833/ENST00000373833.fa @@ -0,0 +1,557 @@ +>1 1:28832455-28865812 +GATTCTCTAACTGCGCATGCTTCTGCGCACGCGCAATAGACATTCCAGGACTTCCGGGCA +CTTCGTAAGGTTTAAAAAGGATGCTTCGCGTTTTCTCTCTCCTTTTTGGAGACAGATTCG +CAGTGGTCGCTTCTTCTCCTTGGTAAGTGTGATCCTTGGTAAGTGTGATCAGATGCTTGC +CACCGGAGTTGTGGGTCTAATGCTATAGATCAGTAGCCGAGCTTCCCTAGGAAGATCATA +TAGTATTTTATTTATTTACTTTTTTTTTTTTTTTGAGACGGAGTCGGTTTGTCACTCAGG +CTGGACTGCAGTGCTCGTTGCAACCTCCGCCTGCCGGGTTCAAGCGATTCTCGTGCCTCA +GCCTCTCCAGCAGCTGGGATTACAGGCACGTGCCACCACGCCCGGCCAATTTTTGTATTC +TTAGTGGAGACGGGGTTTCGCTATGTTGGTCAGGCTGGTTTTGAACTCCTGATTTCCGGT +GATCCACCACCCTCGGCCTTCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCGCCTGG +CCGGAAATCATGTAATTTAAAACTATATATGGGTGTCTTAGGCGGCATCGGTCCCAACTC +TAAAGTACGCGTTAGACGGGCCTGGGCCAGAAGTGGGCCATGGAGACCTCGGGACCCGCA +GGGCTGCCGCCCGACCCAGCGAGCCTCTGAAGGTGCACCGCCACCCCCACTGTTTATCTT +ACTGCCTCATAGTAGGCACATTGTCGTTCTCAATATAATTGCACACAGTTTTATTCTGGA +TCCTCATTTGCCTTTAAGAATTTTCTCAATTTTTCTTTTTATTTGATCGCACCACTGCAA +CCTCCGCCTGCTGGGCTCAAGCAATTCTCCTGCCGCAGCCTCCCGAGTAGCTGGGACTAC +AGGCGTGTACCACCGCGCCTGGCTTATTTTTGTATTTTTAGTAGAGACGGGATTTCACCA +TGTTGGCCAGGCTGGTCTCCAACGCCTGACCTTGTGGTCCGCCACGCCAGGCCGAAGATT +TTCATAATTTGGAAGCATTGCGTTTCGTAATTATGCTTTCTCGTATTTTTGTGATTTGGG +TCATTTTTATTTTTATATTTTTAGGATTACAGGCGTGAGCCATCGTGCCTGGCCGATTTG +GGGGTAATTAACAAGTCCACGTGTTTCATTTGAATTTAGGATAGCTGGGCCTAATTGTTG +TCTTTGCTTCTGCGGTACCTTCCACATAGTACTAACCGCCTATTGTAAAGTAATTAGAAT +AGCTGAATATGCATGTTACCAGTCTAGAAACCGATTTTTTTTTAACACCCCACTGTGGAC +AGGGTGGAAACTCGTTTGCTTTCTTGTTTAAGATCTGTAGTAACATGAATGGATGAAATT +GTTTCCTATTGGATTCTGTAAATTTATGCGTTACACTGATTGTCCAACGTGGATACACCC +GGGAGGTCACTCTCCCCGGGCTCTGTCCAAGTGGCGTAGGGGAGCATAGGGCTCTGCCCC +ATGATGTACAAGTCCCTTTCCACAACGTTGGAAATAAAGCTGGGCCTCGTGTCTGCGCCT +GCATATTCCTACAGCTTCCCAGAGTCCTGTCGACAATTACTGGGGAGACAAACCATGCAG +GAAACAGCCTTCTAGAGCACTGAATCTGGATTGAAGTCTTTTTTTTTTTTTTTTTTTTTG +GAGATGGAGTCGCTCTGTTGCCCAGGCTGGAGTGCAGTGGCGCACTCCATTGCCTCTGCC +TCCCGGGTTCAAGTGATTATGCTAAGTGATTCTCCTGCCTTGGCCTCCTGAGTAGCTGGG +ATTACAGGCCCCCGCCACCACGCCAGGCTAATTTTTGTATTTTTAGTAAAGACAGGGTTT +CACCATGTTGGTCAGGCTGGTCTCAAACTCCTGACCTTGTGATCCGCCAGCCTCTGGCCT +CCCAAAATGTTGGGATTACAGGCGTGAGCCACCACACCTGGCTGGATTGAAGTCTTAATA +CATGTTTAAGAAAAATTGGCTAAAAAGTAGCCAGGCATGATGATAGGTAGCTGGAGGAAG +GAGAATCGCTGGAGCCCAGGAGTGACCTATACTCAAACCTATACTCCAGTGCCACTGTAC +TCCAACCCCAGGCGATAGCATGAGGCCCCTCGTTGAAAAAGTTTAGGGTTTTGCTGTACT +AATAGATTAATATCTTGTTTTGCAGGATTTGTTAAGGATTCCAAGTAACTCTTATTTGGT +GAGTAAATCTGCTAATTGTTTTTTGCTTATCAGCTCTTTGTCAATGATTTCTGTAATGGA +AATAGGATTGAAGAGACTTTTATTCTAGTTGGTCAGGATTTACCTCTGAGGCATTTAATC +ATTCTCAGAGCAATAGCCAAATATCGACTTTGCTGCATTTTTGTAGGCATGTTGACATAA +CTTCAACATATGCTCTGTTCTGTAAAAATTGCTTTTTTTAGTCAGCTCATTAAAAGTGCA +AAGTAGTAAAAGCTGCCCTAGTGAACTGTAGGAAGCCTAATTGGCTTTATCTACATGTGT +AGCCTGAGCTGAGAAAGATACTAGCCCTTGAAAATACTGTGGGTGATTAGCAATATTGGA +TTTGTCGGTTACTCCAATTCCTCACTAATGAGCATTCCAACGTGGATACCCTGGGAGGTC +ACTCTCCCCAGGCTCTGTCCAAGTGGCATAGGGGAGCTTAGGGCTCTGCCCCATGATGTA +CAGTCCCTTTCCACAACGTTGAAGATGAAGCTGGGCCTCGTGTCTGCGCCTGCATATTCC +TACAGCTTCCCAGAGTCCTGTGGACAATGACTGGGGAGACAAACCATGCAGGAAACATAT +CTAGTATACTAGATTTTAAGTTGAAGTAGGATCTTCAGGAGTCTAATCATTATTTCTTTT +CTTTTAGGAGAGAAGACGATCTGCACTTCGCATTTTGGCATTGACATTTAATTTTAGGGT +CCTTTATATAGAAGGGAGAGTAGGTAAACTGATTTTTTTTTTTAACAGGGAGGGTTTGAC +AATCTTTGGCAGACTTGGAGCAAAAGATTGAGGTGCATTTCATGCCTCCTTTTGAGAGTC +TTGCTCTGTCGCCCAGGCTGTAGTGCAGTGGCGCAATCTTGGCTGCAACCTCAGCCTCCC +AAGTAGCTGGGATTACAAACATAAGCCACCACGCCCAGCCCTCATACCTCTTTTAAAAGT +CGACCTGTTTTGCAGAAAGTCTGCTGTTTTTGTACTAAAGGCTTTGGAATTTGGCATTTA +GCTAGGAATGCACATTCTTTCACCTCATTCATACTTTAAGAACCACAGAAGTGACTCTGC +TTGGCCAGAAGGCACACTGTGTTGGTGGTTATATTAAAAGTCCTTGAGTATTTTGCTTTT +CATGATCTTGCTCACTGCAACTTCCGCCTCCCAGGTTCAGGCGATTCTCCTGCCTCAGCC +TCCCAAGTAGCTGCGACTACAGGCGTGTAGCACCACACCTGGCTAATTTTTGTATTTTTA +GTAGAGATGAGGTTTCACCATATTGGCCAGGCTGTTCTCAACTCCTGACCTCGTGATCCG +CCCACCTCAGCCTCCTAAAGTGCTGGGATTACAGCTGTGAGCCACCCTGCCCGGCCACTT +TTGTATGATTTCTAATGTATTTGTAATTTACCTAACAAATTGCCTAATCTGCTATGTTAA +TGTATTTATGAATTAAAATAAATACGACTGCATGTTTGTGGTTCATTTTTGTGGAGGTGG +CTGTGGTGACATCAGCCAAGAATCTGAATGGTACTGTTGAAGGAAACTAGCATGATAGCT +TCAGTTCTAAAGGCCCTGAAACCTAGTCTCAGGTGGGTCCCCCTTGGGTTCACTTTATAT +TGGCAGTTTATTGGGAAAATGGATATTAGGTCCTGACCAATAGGACCGTAAGTCTGGGTT +GAGTGCAAGATGAGTTAGACCGATTCTTTAGCTTCCTGCAGTGTAGTGGAGGAAAAATCG +ATGGTAGCAACGGGAGGTTGTATCCCTAGCTGATGAGTTGTATGAGCCTCTACTACCTGG +CGCACCTCCGCCTGAAGATTGCCAGAATTGCTTGCCTCATGACGTGAGTCACAATGGAAA +CTTTGTCAAGCCCCCTGCACTGGCTGCCAACATAAATGTTCAGTACCCTGAAGGATGGGA +CTGAAGGGGGATCATCTAGAAGGTAAAGTTACCTACTGGCATAGGGGAGGTGGGACAGCC +GTTAAGCCATTTGGAACTTGATGGAGACAGGTTTGAGGGAGGTGGGTGAGATTGGAGTTT +GGTGGACTGTAGAGCTTGCTTGCCAAGGTGTTGAGGTCAGGGTTGGTTTGAGAATGGAAG +CTAGTTACTAGCTATGATTGTGGGGGAACACAGCTTGATTTTTCTTACAAGCTAAGAGGA +GTGAGGCAGTGTTTAAGAGGGCATGTTAAATGCAGCCAGGCTTGGTGGCTCACACCCGTA +ATCCCAGCACTTAGGCTAAGGCAGGCGGATCACAACATCTAGAGATCCTGGCCAACGCGG +TGAAACCCTGTCTGTACTAAAAATACAAAATAACTGGGCATGGTGGTGTGCACCTGTGGG +AGGCTGAGGCAGAATTGCTGGAACCCGGGAGATGGAGGTTGTACTGAGCTGAGACCTTGC +CACTGCGCTCCAGCCTGGTGACAGAGTTAAGTCTCAAAAAAAAGGCATCTTCCTAAAGCA +ATTGTATTTGTGCTTACCTGTGCCAGGCACTGTTCTAGGTAAGCACTAAGTGGGCTTTAA +TACAGCATATTCCAATGGGGAATCCCAGGAACCAAAAGACTAATTGTCCAAGTCCACAAC +TAGAAGTGGCACCTCTGCAGAAACAAGCATCAAATTCCCTGCTCAGGAAGAAGCCAGATG +AGTCAGCCCCATTCGTCTGTATGCCCAGTCCCATCCGTGTCCTGCTGTAACTACATAGAT +CTCACCTGAGTAAAGTGATTTTTTTCTGAACCAGTGGTTTTAGTATGTTTTCAATCCATA +TACTCAGGTGGGTTTGGGTAACTGCAGTGCTGGGCAGGAAATGAATGAATTTCTATTGAC +TTGCAAGGTAGAGGTGAAGCAAAGCTGTCAGTAGGTGTTCAGGTCCCACTCTGCTAAACT +TCAGCTTGCAATACCCCTTTTTTAGACTTTCCAAACAGGCACTTCTGGCCTTGTTCTTTG +TGTAGGCAGACAGTATTGGTTGCCTATCTTAGGAGTACTAGACTGGGTTTGAATCCTGAT +CCCACCACTTGCTGTTCATGAGACTTTGGGTGAGTTACTCAGCCCCTCTGCCTCAATTTC +ATGTTCACAAAATAAGTGATAAACTACCTCATAGAGTTGTAATAAGGACAAAGGAGTTGG +TATTTGTGAAAAGATTCTTAGGGTCTCTAGATGGAGTGCAGCAGCATGATCACTTATTAA +ATAACATTCTTTTGTGACTTCTCAGAAACCAAGGATACAGTATCCAATTTTTTGTTTTTT +GTTTTTTTTTTTTTTTGAGAGGGAGTCTCGCTCTGTCGCCCAGGCTGGAGTGCAGTGGCA +CAATCTCAGCTCACTGCAAGCTCAGCCTCCCCAGCAGCTGGGACTACAGGTGCACGCCGC +CACACCCGGCTAATTTTTTTGTATTTTTAGTAGAGAAGGGGTTTCACCATGTTAGCCAGG +AAGGTCTCCATCTCCTGACCTCGTGATCCGCCCACCTCGGCCTCCCAAAGTGCTGGGTTT +ACAGGCGTCAGCCACCATGCCCAGCTTTTTTTTTTTTGAGATCTAATCTCACTCTGTCTC +CAGGAGGGAGTGCAATGGAGCCATCTTGGCTTGCTGCAACCTCCACCTCCCGGGTTCCAG +CAATTCTCCCACCTCAGCCTCCCAAGTAGCTGGGATTACAGGCGCACGCCACCATGCCCG +GCTAATTTTTTTTGCATTTTTTAGTAGAGACGGGTTTCACCATGTTAGCCAGGCTGGTCT +CGAACTCCTGACCTCAAGTGATCCACCTGCCTCAGCATCCCAAAGTGTTGGGATTACAGG +CGTAAGCCACTGCGCCTAGCCTCAAGCCTGATCCTTTTTTTTTTTTTTTTTTTTGAGATG +GAGTCTTTGCCTCCCAGGCTGGAGTGCAGTGGCGTGATCTCAGCTCACTGCTACCTCTGC +TTCCTGGGTTCAAGCGATTCTCCTGCCTCAACCTCCCAAGTAGCTGGGATTACAAGCGCC +TGCACCGCACCCGGCTAATTTTTGTGTTTTTTTTTTCAGTAGAGACAGGGTTTCGCCATG +TTGGCCAGGCTGGTCTCAAAACTCCTGACCTCAGGTGATCCACCACGCCCGGCAGAGCCT +TGATCTCTTAACCACTATCCTCACCTCCCCTTTCCCTAAGGATCCACAATGGCCTCACTG +GCTCTTGAAGGCAGGCTGGCACCTTGATCATTCTTCCTGGTCATTAGTATTCTGATCTGG +TTATTTTCCATTTTATGTCCATCTAACCTACTTGGAGGATCCTCAAGAGACTGCATATGT +AAACTCAGTACTTATTCTTGTACTGTGCCTGCCATATAGCAAGCACTGGCTGATTTAATT +TTTCTGTGTTCTTTTTTATTGATTTGTTTTTATCTTTATTATTTTCTTTGCTTATTTTGG +GGTTAGTTTGCTCATCTATTCCTAGTTTCTTAAGCTAGTAGCTGAGCTCATTGATTGGAG +ACCTTTCTTTTTTTCTAATGTAGGCATTTAGTGCTATAAATTTCCTCCAGATACTGTTAA +CAACACACAAATTCTGGTATGTTTTGTTTTCATTTTAATTCATTTCAAAATATTTTTGAG +TTCCTTTTCTATTCTTTGATCTATGGGCTACTTGAAAGTGTATTATTGTTGTTGTATTAG +TGTTGTTCAAATCTATCCTTGCTAGTTTCTTTTTTTTTGGAGACTGCGTCTCCAAAGGCT +GGAGTGCAGTGGCACAATCTTGGCTCACTGCAAGCTCCGCCTCCTGGGTTCACACCATTC +TCCTGCCTCAGCGTCCCCAGCAGCTGGGACTACAGGTGCCTGCCACCATGCCCTGCTAAT +TTTTTGTAGAGATGGGGTTTCACCATGGTCTCAATCTCCTGACCTTGTGATCCACCCGCC +TCGGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACCGCGCCCAGCCTCTTTTTTTT +TTTTAGACAAGAGTCTCACTCTGTTGCCAAAGCCAGAGTGCAGTGGCACAATCTCAGCTC +ACTGCAACTTCTGCCTCCGGAGTAGCTGGAATTACAGTCACGCACCACCACGCCCAGCTA +ATTTTTTTGTATTTTTAGTAGAGATGGGGTTTGCGCGGCTGAAGTGCAGTGATGCGATCT +CAGCTCACTGCAACCTCTGCCTCCCAGGTTCAAGCAATTTTCATGCCTCAGCCTCTGGAG +CAGCTGGTACTACAGCATGCACCACCATGCCTGGCTAATTTTTTTGTATTTTAGTAGAGA +TGGGGTTTCACCATGTTGCCCAGGCTGGTCTCAAACTCCTGAGCTCAGGCAGTCCGCCTG +CCCTGACCTCCCAAAGTGCTAGAATTACAGGCATGAGCCACCGTGCCTGGCCTTATTTTA +AAATTTTATTTCTTGTAGGTAACATGTTGGGTTTTTCAGTATGACAGTCTATGTCTTTTA +ATTGGAGTGTTTAGGCTATTTACTTTTTTTTTTTAAGACAGGGTCTCACTCTGTCACCCA +GGCCAGAGTTCAGTGGCAAGATTATGACTCACTGCAGCCTTAAACTGGAACTCCTGGGCT +CAAGCCATCCTCCCAGCTCGGTCTCCTGAGTAGTGAAGACCACAGGCATGTGCCACTATG +GCTGGCTAAATTTTGTATTTTTTGTAGAGACAAGGTCTCATGATGTTGTCCCAGCTGGTC +TTGACCTCCAGGGCTCAAGCAATCCTCCCACCTTGGCCTCCCAAAGTGCTAGGAATACAG +GCATGAGTCACCATGCCCAGCCATATTATACATTTTTAACTTACAATAGTCCACATTCAA +TTGATATTAAACCAGTTCACTTGTAGTATAAGAATCTTCCCCAGCCTGGCCAATATGGTG +AAACCCCGCCTCTACTAAAAATACAAAAAAAAAAAAATTAGCCAGGTGTGGTGGTGCTCG +CCTGTAGTCTCAGCTACTTGGGAGGCTGAGGCAGAAGATTGCTTGAACCTGGAAGCAGAG +GTTGCAGTGAGCTGAGATCGTGCCAGCCTAGGCAACAGAGCAAGACTCCGTCTCAAAAAA +AAAAAAGGCGGGGCCCGGTGGCTCACGCCTGTTATCCCAGCATTTTGGGAGGCCGAGGCG +GGCGGATCACGAGATCAGGAGATCAAGACCGTCTTGGCTAACACGGTGAAACCCCATCTC +TACTAAAAATACAAAAAATTAGCCGGGCGTGGTGGCGGGTGCCTGTAGTCCCAGCTACTA +GGGAGGCTGAGGCAGGAGAATGGCATGAACCCAGGAGGTGGAGCTTGCAGTGAGCCAAGA +TCGCGCCACTGCACTCCAGCCTGGGCGACAGAGCGAGACTCCGTCTCAAAAAAAAAACAA +AAAAAAAACCTTCTGGCGGCCTGGTGTGGTGGCTCACACTTGTAATCCCAGCACTTTGGG +AGGCTGAGACTGGCGGATCACCTGAGGTCGGGAGTACAAGACCAGCCTGACCAACATGGA +GAAACCCCGTCTCTACTAAAAATACAAAATTAGCCGGGCATGGTGGCACATGCCTATAAT +CCCAGCAACTCGGGATGCTGAGGCAGGAGAATTGCTTGAACCTGGGAGGCAGAGGTTGCA +GTGAGCCGAGATCATGCCATTGCACTCCAGCCTGGGCAACAAGAGCAAAACTCCATCTCA +AAAAAAAAAAACAATCTTCCGGCTGGGCACAGTGGCTCACGCCTGTAATCCATCCCAGCA +CTTTGGGAAGCCAAGGCAGGCAGATCACGAGGTCAGAGCGAGACTCCGTCTCGAAAAAAT +AAATAAATATTTCTTCCATTTCTCACTATATAGTCTTTGATATTGTCATGTGTCTTACTT +TTATATATGTTATAAAACCCACAGTACATTATTACAGCCAGAACCTCCATATCAGCCAGT +TGCGATGGCTCACTCCTGTAATTCCAACACTTTGGGATGCCAAGGCAGGCTGACTGCTGA +GGCTCAGAAGTTCAAGACCAGCCTGGCCAACATAGTGAAACCCTGTCTCTACCAAAAATA +CAAAAATTAGATGGGCAATTAGCTGGACGTGGTGGTGCACGCCTGTAATCCCAGCTACTC +GGGAGGCTGAAACAGGAGAATTGCTTGAACCCAGGAGGCAGAGATTGCAGTGAACTGAGA +TCACGCCATTACACTCCAGCCTAGGCAACAGAGTGAGACTCCGTCTCAAAAAAAAAAATT +AGCTGGGCATGGTGGTGCACATCTGTGGTCCCAGCTACTCGGGAGGCTGAGGCAGAGGTT +GCAGTGAGCCGAGATCCTGCCACTGCACTCCAGCCTGGATGACAGAGTGAGACTCTTGAG +ACAAACAACTGGGGCTGGGCGCAGTAGTTCACACGTGTAATCCCAGCACTTTGGGAGGCC +GAGATGGGTGGATCACTTGAGGTCAAGAGCTCAAGACCGGCCTGGCCAACATGGTGAAAC +CCTGTCTCTATTAAAAATACAAAAATGAGCCGGGCATGGTGGTGCGTGTCTGTAATCCCA +GCTACTCTGGAGACTGAGGCAGGAAAATTGCTTGAACCCAGGGGGCAGAGGTTGCAGTGA +GCCGAGATTGCACCACTGCACTCCAGCCTGGGCAACAGAATGAGACTCCATCTCAAAATA +AAATAAAAAATACAAATACAAAACTAAAAAAATAAAAATAAAGGCCAGGTGCAGTTGCTC +ATGCCTGTAATCCCAGCACTTTGGGAGGCCAAGATGGGCAGGTCACCTGAGGTCGGGAGT +TCCAGACCAGCCTGGCAAAAATGGTGAAACCCGGTCTCTACTAAAAATACACAAAATGGC +CAGGCGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGTAGGCTGAGGCGGGTGGATCA +CCTGACGTTTAGGAGTTCAAGTCCAGGCTGGCCAACATGGTAAAACCCCGTCTCTACTAA +AAATACAAAAATTAGCTGGGCATGGTGGCAGGCGCCTGTAATCCCAGCTACTCAGGAGGC +TGAAGCAGGAGAATTGCTTGAACCCAGGAGGAAGAGGTTGCAGTGAGCTGAAATCGTGCC +ATTGCACTCTAGCCTGGGCGGGTCAGGAGTTCGAGATCAGCCTGGCCAACATGGAGAAAC +CCCATCTCTACTAAAAGTACAAAAATTAAGGCTGGGCGCGGAGGCTCACGCCTGTAAGCC +CAGCACTTTGGGAGGATGAGGTGGGTGGCTCATGAGATCAGGAATTCAAGACCAGCCTGG +CCAAGATGGTGAAACCCTGTCTCTACTAAAAATACAAAAATTAGCTGGGTGTGGTGGCAG +GCACCTGTAATCCCAGCTACCTGGGAGGCTGAGGCAGGAGAATTGCTTGAACCTGGCTGC +AGTGAGCCGAGATCGCACCACTGCACTCCAGCCTGGGCAACAGAGTGAGACCCCATCTCA +AAAAAAAAAAAAAAAAGAGTTGAGGTCTCCTTCCACCACTTGTGTGAAGACCCCAGAAAA +CTTGCTTTACCTCTTTAAACTTCAGTTTTCTTATCTTCCAACTGCCATGAGGTTTTTGTG +AGGAACAAATGAGCTGACATGGATGTTTCTGTAGTTAACAAAATAAAGGGTCTTACAAAA +TAGGCAATAATAATAATAATCACTTATTATTATTACATGAAGCTACATGAATGTGTAAGA +TCTTGGAGGAAGACAGCAGAGAGAGAGAGAGAGATCAGAGATCCCAGGGTTAAAAGTTGG +AGAAATTTCACAGTACATCATCCAAAAGAGGAGTCCATGATGGAGGCAGAGGTAAACTTG +GAGAGGTAAGAAACCCTGAAGACAGGGGAGTGCTTTGTGGCAGGCTCTGCATATAAGAAT +TCAGCCTGGCCAACATGGCGAAACCCAGTCTCTACTAAAAATACGAAAATTAGCCAGGCT +TTGTGGCAGGCACCTGTAATCCCAGCTATTTGGGAGGCTGAGGCAGGAGAATCGCTTGAA +CCTGGGAGGCAGAGGTTGCAGTGAGCCGAGATCTCACCATTGCACTCCAGCCCGGGTGAC +AAGAGCAAGACTCGATCTCAAAAAAAAAAAAAGTTCAGTTCAGTTGGTAAGAACTCATCA +AAAGTGTCCATCTAGACTTTGGGTGCCGTAGAATGACTCAGAGTCTGAATCAACATGAAA +TCGAGAAAACGTCCTTTGCAAGGGTTTCAGGGAACACCTGAAATCCTGAAGAACTGTTTG +TATCCATCCTGAAGAATGGGTGTTAATAAGAGACAGCCTTTTCTTGGTACCTGTTTTCCA +TCTCTAACCCAACCCCAACTCACACCCTTCTATTTTATCTGGTCTCTCTCATTCCTCTTG +CTCCTCCCCACTTGGCTCCCGTTTTCCCCAAGTCCATTCTCTATTTTGTTCTATAAGATC +TGATCATATTAGGATGCTCTTGTAGCTCATAAGAAGATGACTGGGTGTTCACACGCATAT +GAGATGTGCCTCCCTCAAACCTTGTTAAGACATGGGCACATACCCATCTGATGTTAACTC +ACGGGGAAAAAAATCTGATCATGCCATTCCCGTGCCCAAATTCCCATATATCCCTACTGC +CTCAGGATAGAGGCTGGACCCCTTAGACACACAAGACCCTGTATCCATGATCTGTCACTC +CCACAGGCACCCTCTACTCCCATCTACTTGGCAGTTTCCCACAACCTCCCTGGGTTCTCG +TGGTTCCCTGTCATTGCAAACGTCGCTTCTCCTAGGATGTCCTGCCCCCCTAGACTTAAC +TTGGAAAGCTGTTCTTAAGCCCCGGACTGAGTCAGATGCCCCTCTGGGTATCCCTGTCAT +AGCGTTGTGTGGTTGTTGATAGTCTGATTTTTCAACCTTCTCCATGCCCTCTTGAGGGTA +GGGAAGATGAGTATCTTTTTTCTCCGTACAGACCCTACCGCACAAGATTTTCCTAAACAG +ACCGAACTCAAGGAGTCTTTCTGGTTGTTAGTCCACGTGTCCCGATTTGGGGTTTCCAAA +ATACACGCCCACTGGAACCGGGCCAGGGGAGCCAGCCTGGCCAAGGGCTCCCCCAGCCCG +GCCAAGGGCTCCCCCAGCCCGGGAGCGCGCCACATGCAGATCCTGGGATGGCCGCCAGGG +GCCGCCGGGCTCTTTGTTTTCCTTTCTCACCCGGGTCGGGGCCAGAGGCCTGCAGAGCGC +ATGCTCTGGGGCAGTTCGCGGCCCGGCGGGGAGCGCCGGAGTTCCTTGTGGCCGACGTGC +ACCAAGGTAGGTCTCGCCTGGGACGCGCGGAGGGTCCGGGCAGAGGGCGGTAAGCGGAGC +GGCCACAGCCGGAGCACGGGCCGGTCCACGCGGGCCTAAGTCGCTGCCCGCTCTCGCCCG +TGTCGCGCGGCGCCGGCCCCACGTGAAGCCCGGAGGCAGGAAGGCGCGGTGCGGGCTCGC +GATTCCCCGGCCCCGCGGGGCGCTCCAGCAGCGGCTGGGCGCTGCCTCGCTGGAGCTAGG +GCCGCGCGGCCCCTCCGCCGCCGCGCCTCTCACGCCCGCACCGCGGCGCCCGCGCAGGCG +GGAGATTCAAACTGCGCGAGCGCGGCGGGCCGGGTGCGCGCGGCCGCCCGGGCGGGGGAT +GGGTCTCTGCCGCGAGGAGGATGGTTTTGTCCGGCATGCGCTTGGAGAAGGCGGTTTGCA +GATCGGGGAGGGAGCCCTGCCCGGGAGAGGGTGGGTCGTAGGAGCTCGAGGGTCTCCCGC +TGTGGACCTTTGGGAGCCGTGTGTCTTGAACTCCGCAGCAGCTCAGTCTGTCAGCAGATT +ATTTGCTGGCCATTTATTGCGTCCCTCTCTTGCGGGGCTGGGGGACAGTAGTGAGAAGAG +CAGGCCCGTGTCATTAGCGAACTATGCCCTTGAACCCAGGCGACGGACGCTACTGGCAAG +TCATTCATACGTCACATATTGACCTAACTTCGACCACGTGTGACTTGTGTGCCCTAGCAG +AAGTTGAGTGTGTGGGGTGTTACGGGGAGCCCTCAGGGGGATCCCCCACCCTGCCCAGGA +GGCTCAGGGATGGCTTTCCAGGTGAAGTGACTCTTGAATGGGGTTTTGAAGGAACAGAGT +TTTTCAGGCAGTCTGAGGGTAGTGGGATTAGGGTGATACAGGCAGAGGGATTGCACGTGC +AACGGCATGAAGGTATAGGTATTGTGGTCAGGGATACCACAGGTCTTGAGGTGACTGGAG +GAGGAGAGTAACAAGATGATACAGCAGGGGCTGGGTCACGAAGCGTCTTGTGTGCAAGAC +TAAGGAACTCTGCGGGGTGGAGGAGGCAGGGAAGATTTCCCCCAAGAAGGGTATCAGAGT +GAAACCTGGACAGATGAATTAGGAGTTCACGAGGCTCCTGTTTCAAAGACATCCCAAGAG +CAGGAATCCTGTTCTGTTCATCGTTACAACTTTCTCATCAGATGCCCTTGGGCAACCCAC +CCAGTCCCCCAGAGCATTGGTTTCCTTATCTGTAAAGCAATGGTAGGGGGCATGTGGTGA +GGATATAATTTTTTTTTTTTTGAGACGGAGTTTCCACTCTTATTACCCAGGCTGGAGTGC +AGTGGCGCGATCTCAGCTCACTGCAACCTCCACCTCCTAGGTTCAAGCAATTCTGCCTCA +GCCTGCTGAGCAGCTGAGACTACAGGAACACACCACCAGGCCCAGCTAATTTTTGTATTT +TTTTTTTTTTAGTAGAGACGGGGTTTCACCATGTTGGCCAGGCTGGTCTTGAACTCCTGA +CCTCAGGTGATCCACCTGCCTCAGCCTCCCAAAGTGCTGGAATTACAGGTGTGAGCCACC +GCACCCGGCCAATTTTTTTTTTTTTTCTGATACAGAATCTTGGTCTATCGCCCAGGCTGT +AGTATAGTGTCGTGCTCTCAGTCGCTGCAGCCTCCACCTCCCGGGTTCAAGCGATTCTCC +TGTCTCAGCCTCCCGAATAGTAATATCCTATAATTTTCATAAAGCAGTGAAGTTGTGTGT +CCCTTCCCCCAGGAAAAATGAACACATAGGCCCAGGCACAGGTTGTATAGAACGGGGATC +CCAGGTGAGAAACTCCTAGTGTGAAATATACCACCTGTGTGCCTGGCATAACAGCAGCTC +ACCAAATGTATATTGTTGACACATGAGCCCTCTCCTCCCTTCCCTCCTGGGGACCTTACA +CACAGAGATTTTTCAGCCTTAGTCTGGCAGGCAAGTTCTTCCTCCTGGTGTGGGGGACGG +AGGGCACAGCTGCAGTGGCCTGGGAGGGCTCTGTCTCCTTTTACAGAAATCGAGGCTGTG +GTGAGGTCACTGGAGGTCAGGGCAGGAGCACCAGGCTCCGGGCAGACTGTCTAGACTGGC +GTGCCTACCCACTTTCTTCAATAAATAAGGAAGGTGAGGTGGGGGTAGGGCAGCTCCAGC +TCTGGTGGAGCATGGTCATGAGACTGGGATTTCATTCCACCTCTCTGTGACCTGGGTCAC +CTTTCCCTGAGCCTCATCTTCCCCTTAGCTGTAAAACTGGGATGAGTCTGCTCACCTCAA +AGGGCAGCTGTGGGCATTCAGGAGTGCCTGATGGTGGAAGCTGACTCTGTAGCCGACTTA +TCTGTGACTGTCTCACTCTTCTCCCAGAGACTGTATGCTCCTTGAAGATGGAAGCTGTGT +TGTGTGGGGCGGGGTGGGGAAGCATGATGCCAAAAGCCAACTCCTTATTCCCAGCCCAGA +CACTCACTGCCTGGTTAAGAAAACAGCCAGAGAGGCCGGGCTCGGTGGCTCACGACTGTA +ACCCCAGCAATTTGGGAGGCCAAGGTGGGCAGATCACCTGAGGTCAGGAGTTCAAGACCA +GCCTGGCCGACATGGTGAAACCCCGTCTTTACTAAAAATACCAAGCAGTTAGCCAGGCGT +GGTGGCTTGCGCCTGTAGTCCCAGCACTAGGGAGGCTGAGGCGGGAGAATCGCTTGAACC +TGGGAGGCGGAGGTTGCAGTGAGCTGAGATCGTGAGTCTGAACTCCAGCTTGGGCAACAG +AGTGAGGCTCCATCTCAAAAAGAAGAAAAGAAAAGCAAATAAAGGAAAACACACCCAGAG +CAGTGAGAGAAGTCTGTATACAAGACCCATTTGTGCAGTAGAGGCTGTGCAGGCAGGTAC +CGGGAACAGGGCTCCACCTTTTAGAAGGTGGTCCTCTGGCCGGGAGCAGTGGCTCACGCC +TGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGTGGATCATGAGGTCAGGAGATCGAGAC +CATCCTGGCTAACACGGTGAAACCCCGTCTCTACTAAAAATACAAAAAATTAGCTGGGTG +TGGTGGCAGGCGCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATGGCGTGAA +CCTGGGAGGCGGAGCTTGCAGTGAGCCGATATCGCGCCATTGCCTCCAGACTGGGCGACA +GAGCGAGACTCCACCTCAGAAAAAAAAAAAAAAAAAAAAAAGAAGGTGGCCCTCCATCCC +CTGCCCTTCCCTGGCGATTGCCAGCCCAGTGCAGGGCCTCAAGTCTTCCATTTTGGAGAG +GAAGCCTCTGGGACTCAAAGAGCACTCAGGTGCCGTCTCCACCGCAGCAGGGAGTTGTCG +CCACTGTCCTTCCCCACATCTGTGGGTGGATCTGTCACCACCCACCCCACCTTCCCTCAG +GCTCTAGCTGCCTCATTGTCTCCTCTCTGGTCTCACCATCCTCTCCTCAGCTGGCTTCTG +CTCTCTGCTTCTTGGACTTGGCCAAGTGCATAGGGGATACTGGGGAGGCCTGCCCAGACT +GCCTTAGCCCCTGCCTGGACCAAGGTCTGCCTTCAGAATCAGTCAGATAGGCCTGGGTTG +CTTTTCTAGGCTGCCCTTTACTTGCTCTGTGAACTTAGGCCGATAAAGTTATCTTTCTGA +GCCTCAGTTCCTTAACTGTGAAATAGGAGTGACAGTGCTGCCTTCTTCAGCTTCCTGTGA +GGAATAAAAGGGTTTTGCATATGGAAGATACAGTGAGTTAGCCGGTGCCCCCAGGGGCTC +ATATTTTAGGAAGTTGATTGGTATGGTGGACAGGCATGTAAATTAAAGTGATTGTGATCC +AAAAGTCTGTCCCAGTTTCTCAGAGAGAATGACTAGTTCAGGATGGAGGAGGGATCAGAG +GAGGTGACTTTGAGACACCAGTAGATGTTCTTCCAGTGGGATAAGGGATGGGAAGGCGTT +CCAGGTAAAGAGATGCAAATAGTATGGAGAGGACAGTTAGCATTCTGGCCTGGTGGGTCT +GGCAAGGAGATTGTGTGGGAAGAGAAGGGAGGATGTGATAGATAGGAAATGAAGCTAAAG +GTTCTGTCAGTACCCGATGTTGGAGACCTCTAATACCCAGCTAAGAAATGTGGGCTTTAT +CTTCCAGGAAAAGGGGACCACTAAGGAGTCCAAGCAGGCCAGCAGCTTGCTTCAGGTTTG +AGGTTTGGAAAGATCATGAATGAGGCCGGGCATGGTACCTCACGCCTATAATCCCAGTAC +TTTGGGAGGTCGAGGTGGGAGGATCACTTGAGCCCGGGAGTTTGAGACCAGCCTGGGCAA +CATAGTGAGACCTTGTCTCTACAAGAAAAAAAAAAATTACAAATTAGCCAAGCGTGGTGG +TACATGCCTGTAGTCCCAGCTACTCTGGAGGCTGAGGCAGGAGGGTCGCTTGAGCCTAGG +AGGTGGAGGTTGCAGTGAGCCGTGTACGTGCTGCTGCACTACAGCCTGGGCAACAGAGTG +AAACCCTGTCTCAAAAAAAAATAAATATATATATGTATATATATACACACACACATATTT +ATTGATCACGAATGACTTGGAGAATGAGAGGAGGGGATGAGGGTGGGGACCGGAAGACCA +GTGAAAAGTTGCTGTCTTTCCTAGGGAAAGGAGGAGGAGACACAGTTCCAGGCAAGCTGA +GAGACTACTAGGGAGCATGGGGAGGAAGGAGGCAGAAGAAATTTCTTTTTTTTTTTTTTT +TTTTTTTGAGACGGAGTCTTGCTCTGTCACCCAGGCTGGAGTGCAGTGGCGTGATCTCGA +CTCACTGCAAGCTCTGCCTCCCGGGTTCACGCCATTTTCCTGCCTCAGCCTCCCGAGTAG +CTAGGACTACAAGCGCCCGCCACCACGCCTGTCTAATTTTTTGTATTTTTAGTAGAGACG +GGGTTTCACCGTGGTCTCGATCTCCTGACCTCATGATCCGCCCGCCTCGGCCTCCCAAAG +TGCTGGGATTACAGGCGTGAGCCACCGCGCCCGGCCAGAAGAAATTTCTAATAACACTCA +AGGACGCCAGCTCTGGAGTCTGACTAACTTGGTTCAGATCTTGGCCTTCTCTTCCAATCT +TGAGTGAGATACTTCACCTTTCTGAGCCTCAGTTTTCTTCTCTGTAGAGTGGGATCATTG +TGGCCAGCTTGTAGTGAAACGCTCCAGAATATTAGCCAAACACAACTAAGGAGATGTTGA +CTGGGTTTGTTCCATCCATGATAACAGATTTTTTGGTTAATGCCCCATGACACCAACACT +TCATATAGCCCTTATGTGTCTGACTCCATTCCGGGCTGTGCTCATGGCAGCCCAGCCATC +AGCACCAACTGTGCTGACATAATTGTTTCCTGCTTTTTCTCCTGACTTCTTATTGTGAGT +ACTTTTCATGCTAATACAGTCTCCCTCCCAGGCACAGCAGACTGCTACAGATTATTCTGA +TGAACTGATGAGATGTTTGCCTTGGCATACAGCTGTCTATCTAAAACAAGGGTGCCTCTT +TTTTTGGTGGAGGGACAGAGTTTCACTCTTGTTGCCCAGGCTGGAGTGCAATGGTGCAAA +CTCGGCTTACCACAACCTCCACTTCCTGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCCG +AGTAGCTGGGATTACAGCACGCGTCACCACGCCTGGCTAATTTTGTATTTTTAGTAGAGA +TGGGGTTCCTCCACGTTGGTCAGGCTGGTCTCGAACTCCTGACCTCAGGTGATCCACCCG +CCTTGGCCTCCCAATCTGCTGGGATTACAGGCGTGAGCCACCGTGCCCGGCCACAAAGAT +GCCTCTTATATCCCACATCCCTACCCCATCTAACTTTGCCTGCCTGACATCCTTTCTGGG +ATGGCTCCCAAGCACTTCAGATTGAATGAAAACACCTAGCAACATGGAGCTTCACGTCTC +TTCTCTCCTGTTTGTTCAACAGTGTTCTCTATCTCACTACATGGAAGTCTACCATCTACC +TGGTCATTTAAGCCCAAGCCTGGGAGTCTTTGTGTTTGGCCAAGCTCATAGGGGGATCTT +GGGCAGGCCTGCCAAGAATCCTCTGGACTTTTTTAGGATGAACAAATCAAGCCAAGTGCT +GTGGCACGTGCCCATGATCCCAGGCTCTTGGGAAGCTGAGGTGGGAAGATCGCTTGAGTC +CATGAGTTCGAGGCTGCAATAAGCTAATTGCACCACTGCACTCCAGCCTAGGTGACAGAG +TGAGACCCCCTCTCTTAAAAAAATAAAATAAAAGGCCAGGCATGGTGGCTTACACCTATA +ATCCCAGCACTTTGGGAGTCCAAGGCTAGAGAATCGCTTGAGCCCAGGAGTTCGGGACCA +GCCTGGGCAACATGGCAAGACGTTGTTTCTGCAAAATATACAAAAATTAGCCGGGCGTGG +TGGTGCACACCTGTAGTCCCAGCTATCCAGGATGGCTCAAGCCCGGGTGGTTGAGGCTGC +AGTGAGCCATGACCATGCCACTGCACTCAAGTCTGGGCAGGACCCTGTCTCAAAAATAAA +TACAAAGGATGAACAAATTATGAGAGTAAAAAAGGGTTAGTCTCCTTTATCCTTGCTACA +CCTCCTCACCCAAAGCCAAGCAGTAGTGTAGCAGGATAAGCCGCAGACAAAACCCCCCAG +ACACCCAGTTAAAGAAGGAAGGGCTTTATTCAGCTGGGAGCTTTGGCAAGATTCACGTCT +CCAAAAACTGAGCTCCCCGAGTGAGCAGTTCCTGTCCCTTTTAAGGGCTTACAACTCTAA +GGGGGTCTGCATGAAGAGGTCGTGATTGATTGAGCAAGCAGGGGATATGTGACTGGGGGC +TGCATGCACTGGTTATCAGAACGGAACAGAACAGGACAGGGATTTTCACAGTGCTTTTCC +ATACGATGTCTGGAATCTATAGATAACATAACCGGTTAGGTCAGGGGTCGATCTTTAACC +AGACACAGGTCGCGGCGCCAGGCTGTCTGCCTGTGGATTTCATTTCTGCCTTTTAGTTTT +TACTTCTTTGGAGGCAGAAATTGGGCATAAGACAATATGAGGGGTGGTCTCCTCCCTTAG +TAGTAAAGCACTATAAATATTTGTGGATTTACAACCATTTCATTCAGTCTTGATGACAGC +CCTGAGAAGTAGTCATTGCATCCCCTTTTATAGATGAGGATACAGTTCAGAGAGGTTAAG +GCAACTGGCCAGCCACAAGCTCTGGAAGGTGAACCCAGTTCCCTCTAATCCCAAAGAATG +TGCACTTTTTAGTGTGGGACAAGGGGTCTCAAAAGACAGGTGGGAGGATTCTCAGCCCTG +GGAGAATAAAAGTTGGGTGAAGTTCAGAACTGCCACCTCATCAGTCAGAACTGGGCCAGT +GACAACCTGCAGAAGCTCAGCCTGCAAAGGCTTATCAGGATTCTAGACCTTTGGTTACTT +TCCCATCTTTAGTATTTAGTTCTCCTTCCCCAGGATAATCAGCAGAAAAGTGCCTGGCCT +TGTGTCCATATACCATGGAGGGGAGAGCTAGAGAGGCGAGGTTCTCGGGAACCACTAGAA +GGAAGGAATGAGGGGGCTGCTGGTTAGGCCCAGAGCTGAGACCGAGAAGGGCTCTTGGAG +TTCTCCTTCCCTTCGTAACATTAGGTAGAGGCTTAGACAACTTGATTGTTTTTCATGACC +TTAAAGACTGTGGCTCCGGCCGGGCATGGTGGCTCACAGCTGTTGTAATCCCAGCACTTT +GGGAGGCTGAGGCGGGTAGATCGCTTGAGCCCAGGAGTTCTAGACCAGCCTGGGCAACTT +GGCAAAACCCTGTCTCTACAAAATATATAAAAATTAGCTGGACACTGTGATGCGCACTTG +TAGTCCCAGCTATTCTAGAGGCTGAGGTGGGAGGATCACCTGAGCTCAAGAGGTCAAACC +TGCAATGAGCCGTGATTGTGCCACTGCACTTGAGCCTGGGCAACAGAGAGTGAGATGCTG +TCTCAAAAAAACAAACAAACAAACAAACAAAAACAAGTACTTGATGACTCCATTGGGGTC +AATTATGAAGAGACCTCTTAGTGCAAGACCAGGACCTTCTAACAGCACACCGAAGTCTCG +AGAAATTCGCTTAGTTAAATCTGACAAGGGTGCGATGTTTATGTGGCCCAAAGCACCATT +CTTTCTTGGTGTATTTATCCAGGCAAGACGGCTAAAGTGGGAATCCACTGAGACTGCAAC +AACTTCAAAGTTCACATCGTGAAATTCCTTAGCTTTGTCACTAGAAGCAACAATTTCTGT +AGGACACACAAAGGTGAAATCCAAAGGATAGGGCTGGGCGCGGTGGCTCACACCTGTAAT +CCCAGCACTTTGGGAGGCTGAGGTGGGTGGATCACCTGAGTTCAGGAGTTCAAGACCAGC +CTCACCAACATGGTGAAATCCCATCTCTACTAAAAATACAAAAATTAGCCAGGCGTCGTG +GCAGGCGCCTGTAATTCCAGGTACTCAGGAGGCTGAGGCAGGAGAATTGGCTTGAACCCA +GGAGGGGGAGGTTGCAGTGAGCCGAGATCGTGCCACTGCACTCCAGCCTGGGTGACACAG +CAAGACTCCGTCTCGGAAAAAAAAAAAAAAAGAAAGAAATCCAAAGGATAGAAGAAAAGC +ACCAAATATTTCCCCTCAAAGTCATCAAGGCTTAGGTCTTTGAACTCTCCATTGACCACG +GCTGTACCCTTAAAATAGGGCGCATGCTGGGTGACATCAGGTGCATGGTATGAGGAACTG +GTACCAGAATTTTGCTTGACCGGAACCAGACCACAATATGTTTGTCAAACTTGTTCTTCC +AGAAGCAGCAGGCCTGAGGGCTGCAGTGGCAGAAATGCCCCCAAGGAATGGCACTCACAT +GCCGGGCAACTGATGCTCAGAGTAACCTTCCCACAGCAGCCGCGATCTTCAGTGCATGTG +TGTTTTTGTTTTTTTGAGACAGTGTCTGTCTCTTTCGCCCAGGCTAAAGTACAGTGGCAC +AATCTCAGCTCAATTTAGCCTCAGCCTCCCAGGCTCACGCCATCCTCCCACCTCAGCCTC +CTGAGTAGCCAGGACTTCAGGCGTGCACCACCATGCCCGGCTAATTTTTGTAATTTTTTG +GATAGAAATGGGGTTTCGCCATGTTGCCCACGCTGGTCTTGAACTCCTGGGCTCAAGCGA +TCCTCCTGCCTCGACTTCCCAAAGTGCTAGGATTACAGGTGTGGTGGCACCTTGTCTCTA +AAAAAAATCAATCAATTAAATAAGAAAAGAAAATAGCTCTTCTCCCCCTCTGATTATAAC +AACACATTACCAAAGTTACTGGTGCTTACATGGGGTTGAATGGAGTTATGATGGATATTT +CATTTAATGTTGTTCTTCAATGTTTTAATTTTTTACAACAGACTTAAAAATTTTTTAAAT +ACATGTGGCCAGGCACGATGGCTCACGCCTGTAATCCCGCACTTTGGGAGGCCAAGGTGG +GTGGATCATCTGAGGTCAGGAGTTCAAGACCAGCGGGACCAACATGGAGAAACCCCATCT +CTACTAAAAATACAAAATAAGCCGGGCGTGGTGGCACATGCCTGTAATCCTAGCTACTCC +AGAGGCTGAGGCAGGAGAATCACTTGAACCTGGGAGGTAGAGGTTGTGGTGAGCCGAGAT +TGCGCCATGGCACTCCAGCCTGGGCAATAAGAACAAAACTCTGCTTCAAAAAAAAAAAAA +AAAAAACATGTAATCGGCTGTACGCAGTGGCTCACGCCTGTAATCCCAGGACTTCGGGAG +GCTGAGGCAGGTGGATTACTTGAGATTAGGAGTTTGGGACCAGCCTGGCCAACATGGTGA +AACCCCGTCTCTACTAAAAATACAAAATTTGGGCTGGGCACAGTGGCTCACGCCTATAAT +TCCAGCACTTTGGGAGGCCAAGGCGGGGTGGATCACTGAGATCAGGAGTTCGAGACCAGC +CTGGCCAAACTGGTGAAACCTCGTCTCTACTAAAAATACAAAAATTAGCTGGGTGTGGTG +GTGGGTGCCTGTAATCCCAGCTACTCGAGAGGCTGAGGCAGGAGAATCACTTGAACCCAG +GAGGCAGAGGTTGCATGAGCCGAGATCGCACCATTGCACTCTAGCCTGGGTGACAGAACG +AGACTCCATTTCAAAAAAACAAAAACAAAACAAAACTTAGCAGGGCATGGTGATGCACAC +CTGTAATCTCAGCTACTCGGAAGGCTGAGGCACAAGAATTGCTTCAACCCGGGAGGTGGA +GGTTGCAGTGAGCTGAGATCATGCCTGTGCGCTCCAGCCTGGCGACAGAGTGAGACTCCG +TCTCAAAAAACAGAAAAATACATGTAATGCTCCTTGTTAAACATCTTAGATAATATAGGA +AGATAAAACGAAACAAGTAATGATTATCTATAATACCATTTTCCGAGGTTACCATTGTTA +ATATGGGATATATTTTCTTCCCCACATTTTTCTCACATATTTTTTGTGTATGCATTTTTT +TTCCAAAAAAAAAAAAAATGGATGATAGGCTGTTTTTCTTCCTTTTTTTTTTTTTTTTTT +TTGGTTGGGGGGTGGAGTTTCACTACTCTTTCTCCCAGGCTGGAGTGCTGAGTGCAATGG +CATGATCTTGGCTCACCGCAACCTCCACCTCCTAGGTTCAAGCAATTCTCCTGCCTCAGC +CTCCCAAGTAGCTGGGATTACAGTCGCACACCACCATGCCTGGCTAATTTTTGTATTTTT +TTTTTTTTTTTTGGTGGCGACGGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAACTCCT +GACCTCAAGTGATCCACCCACCTTGGCCTCCGAAAGTGCCAAAGTACTGGGATTACAGGC +GTGAGCCACCGCGCCCAGGCTTTTTTTTTTTTTTTTTTTTTGAGACAGTCTGGCTCTGTT +GCCCAGGCTGGAGTGCAGTGGCTCGATCTTGGCTCACCACAACCTCCACCTCGCGGGTTC +AAGCGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGTGCCCATCACTGTGC +CTGGCTAATTTTTGTATTTTTAGTAGAGACGGGGTTTTGCCATGTTGGCCAGGCTGGTTT +GGAACTCCTGATCTCAGGTAATCCGCCCGCCCCGGCCTCCCACAGTGTTGGGATTACAGA +TGTGAGCCACCACACCTGGCCGTCTGTTTTTCATTCTGCTTGTTTTACTTGGCAATGGGG +AACATCTTTCTATTCAATAGATTGATCTCTGAAAACATCACTTTTGATGGCTTCATACTG +TTCTATCATGAATATACCACATATTTAGTTCACTACTATTGAACATTCGGGTTCTGTTTT +TGTTGTTTTTAAAATGTTATGAAGGATACAGTAGAGAATATTTGTGTAATTAATCTGTGG +GTGCATCCATTATTCTGTTCTTGGGATACATTTTGAGAAGTGGAATTGTTGGGCAATTCC +TCTTAACGTATTTCTAGAGTGTTTGATAAATATTGTCTGATTGGCCCAGGAAAATGTTTG +CCATTTCTCATATGTAGTATTTGACTGACTTTCAGGACAGGAAGATGTCACCCAAGCGCA +TAGCTAAAAGAAGGTCCCCCCCAGCAGATGCCATCCCCAAAAGCAAGAAGGTGAAGGGTA +AGTTGGCCTTGGCCTCTTTGTGGGTACAGGTGGCCCCTTGAAACCCTAAGAACCCGGGAC +TGGGCTCCTTTCTTCCTGAGGCTTGAAGCTGAAGGGTGTGGATGTGCAGAGACCCCACCC +AGCTGGAAGGTTTCCTGTAGCTCATTGAATCCTACCCTCTGGGAATCACAAAGTGGGCAG +AAACTCCTCTCAAAGCACTCAGGCAGCACTGGCACAAAAAAAAAAAAAAAAAAACTAGAC +CCTAGGGCTTCACCCCAGGCAGTGATGCATTATGGTTAGGACCACTGACTTTCCGACATG +GGTTCAAGTCCTTGCTCTGCCACTTTCTAGCTGCTGGGCAAGTCACTTAATCCCGCAGTT +TGGATTATCAACTTCTTAAAATGGCGGCAGCCAGAGCAGCGTCACCCTCTCTGGGCTGTG +TGAGGATGAGATGAGATAATGGCCTGGCAGCATTTGAGGGAGGTGGCTGTGGTTTCCTCT +GTCCTGGGACCCCGGAGGGGGACAGGGAGGAGAGAAAAGCCAGCACCAAACTGGGAGGGG +AAGTGTGGACCCACGCTCAGACAGTGTCTGTCTTTTGCAGACACGAGGGCCGCTGCCTCC +CGCCGCGTTCCTGGCGCCCGCTCCTGCCAAGGTGCCTGCGGGCCGAGCCCTCCTGACCAG +AAAACCCGACCAGGTGGCTCCGCGCCCGGGGCGCCCTCTGTGCTGCCAGCGCGGGCTCCT +CAGCGGTGGCCACATCCTCGGGGGAGGGGCTGGGCGCCATTGGCTGCCCGGGGCTGCGGG +TTGGGGGGCCGCCTTTGGCCCACAGAGAGCCCCGGGCGCGCACCTCCCGCAAATGCCGCT +GTCCGCTCTTCCTCCCGCCCCTCCTGCCTCTCCACTGGATGGTGGAGGGAAGAGTCCGTT +TCTGCAGTGGATTTGCCCGGGAGCTGAACTTATTCACTGGCGGACGGCTTGGGCATGGAG +GAGGGCTTGGATGGAGACTGGGGATTGTTCTCTGACCCACGTAGTCTCCCTTGCTTTCGG +TGCAGATTCTGCTATTATAATTAGCTTTCTGCGGGGCAAGGTGGCTCACGCCTGTCAGAA +GATCGAGACCATCCTGGCTAACACGGTGAAACCCCGTCTCTACTAAAATACAAAAAATTA +GCCTTGCGCGGTGGCGCGCGCCTGTAGTCCCAGCTACTCAGGAGGCTGAGGCAGAGGAAT +CGCTTGAACCCGGGAGGCAGAGGTTGCAATTAGCCAAGATCCACCACTGCACTCCAGACT +GGCGACAAAGGGAGACTCCGTCTCAAAATAACAATAACAATAATTAGCTTTCTTTTCTTT +TTCTTTTTTTTTTTTTTTTTGAGATCAAGTATCACTCTGTCGCCCAGACTGGAGGCGGCA +GTGGCACGATCTTGGCTCACTGCCACCTCCGCCTCCCAGGTTCAAGTGATTCTCCTGCCT +CAGCCTCCTGAGTAGCTGAGATTACAGGCTACTGTTGGCAAGGCTGGTCTCTTAACTCCT +GACCTCAAGTGATCCGCCCGCCTTGGCCTCCCACAGTGCTAGGATTACAGGTGTGAGCCA +CCGCACCCAGCCCTTCTTGCCCTCTCCACCAAGATTCATTTCACAGTATCCAGTGTCTCC +TTGTTTCCCTTTCTCCCCTTTCACGTGAATAATGTGCTCAGTTCTTAATCTCCACAAAAA +TCCTGTGAGAGAGGTACTTTTGTTGTCCCCATTTCACAGATGACAAAACTTAGAAAGTTC +ATACTAACAGTCTGTGGCAGAGCAGGGGCTTCTGCACAGGTTTGTCTGATCCCAGAGCCT +GTGACCTCTCCTCGCTGTCGTCATCCTCTACACTCAGGGTCTATCTTCTTCACCCTTCAG +TCTCACACAGGTCCCACAGCACAGAACCCGGCTTGGTGCTGACACTAGGCCAGGGCGACG +TGGGCCAGCTGGGGCTGGGTGAGAATGTGATGGAGAGGAAGAAGCCGGCCCTGGTATCCA +TTCCGGAGGATGTTGTGCAGGCTGAGGCTGGGGGCATGCACACCGTGTGTCTAAGCAAAA +GTGGCCAGGTAGGTGTTGGGGACTGGCACAGGGTTGGACAAGGCCTGGGGTTGGGTGGCT +TGGGGCAGGGCTTTTGAACCACGCATGTTCACTGTGGAAATGGAGCTGGCTAGTCAAGTG +GGGAGTGGCCTACATGAGAATGGACTGCGAGGCCAGACGTTGCATTAATGAGGGCATCCT +GGGCACAGGTCTATTCCTTCGGCTGCAATGATGAGGGTGCCCTGGGAAGGGACACATCAG +TGGAGGGCTCGGAGATGGTCCCTGGGAAAGTGGAGCTGCAAGAGAAGGTGGTACAGGTGT +CAGCAGGAGACAGTCACACAGCAGCCCTCACCGATGATGGCCGTGTCTTCCTCTGGGGCT +CCTTCCGGGTAAGGCTGGGTCTGAAAGTCTGCATGGTCCCTGAAAGACAGAATTAATTGG +CGGGGCCCCAAAGATAATCCACTTCCATGCCCCCATGGTACTTACTGGTGGGGAGATGAA +AGCCCACAGGTAGAGCTGAGGCCCAGACCCAGGACTCTAGCTTCCTCATGTGGGCCTGTC +CACGCCACTGGCTGCTTCCTTGAATCCGATGTCATCAAGTGTCTGTCCTGGGAAGTGAGT +GGGTCAAGGATGTCCCTGGGTTGAGGCTGATCCAGGAGGCCTGCTGTCTTCACCCATCTC +CCTGACTTCTGTCTCCCCCTCACCTTGCCAGCACTGCCTCTTCCACACTTCCCAGAGGCT +TGGATGGGGCAAGGAGGTGTGGAGGCAGGGATTGTCGCATCTCAGAGTTTCCAAGGTACA +GAGGAGTGTAGTTGAAAAAACAGATTGTGGGTTTTTGTTGTTGTTGTTGTTGTTGTTTTT +GTATTGTTTTGAGATGGAGTTTCACTCTTGTTGCCCAGGCTGGAGTGCAATAGCGCAATC +TTGGCTCACTGCAACCTCTGCCTCCCAAGTTTAAGTGATTCTCCTGCCTCAGCCTCCCAA +GTAGCTGGGATTACAGGCATGCGCCACCACGCCTGGCTAATTTTGTATTTTTAGTAGAGA +CGGGGTTTCCCCTGTTGGTCAGGCTGGTCTCGAACTCCCGACCCCAGGTGATCCACCCGC +CTCAGCCTCCCAAAGTGCTAGGATTACAGGCGTGGGCCACCACACCCGGCCTGATGGGTG +TTTCCTTATCACATCTATTTTGAAATTTTCATGGAGAATTTCAAACACATGAAAGTAATC +AGAATTGGGCTGGGCGCGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGATGCCAAGAT +GGGCAGATCACGACGTCAGGAGATCGAGACCATACTGGCTAACATGGTGAAACCCCGTCT +CTACTAAAAATACAAAAAATTAGCCAAGCGTGGTGGCGGGTGCCTGTAGTCCCAGCTACT +CGGGAGGCTGAGGCAGGAGAATGGCTTGAACCCGGGAGGCGGAGCTTGCAGTGAGCCAAG +ATCGCGCCACTGCACTCCAGCCTAGGGGACAGAGCGAGACTCCATCTCAAAAAAAAAAAA +AGAAGTCCGGGCGCAGTAGCTCATGCTTGTAATCCCAGCACTTTGGGAGGCCGAAGCAGG +CTGATCACCTGAGGGGTCGGGAGTTCGAGACCGGCCTGACCAACATGGAGAAACCCTGTC +TCTATTAAAATTACAAAATTAGCTGGACATGGTGGTGCATGCCTGTAATCCCAGCTACTC +GGGAGGCTGAGGCAGGAGAATTGTTTGAACCTGGGAGGCGGAGGTTGCAGTGAGCCGAGA +TCGCGCCATTGCACTCCAGCCTGGGCAACAAGAGCGAAACTCTGTCTCAAAAAAAAAAAA +AAAAAAAAAAAAAGGAAGTAATCAGAATATCAGAATTATATTTTTTTCTTTTCTTTTCTT +TTCTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTGAGACAG +AGTCTTGCTCTATCACCCAGGTTGGAGTGCAATGACACAATCTCGGCTCAGTGCAACCTC +TGCCTCTCGGGCTCAAGCAATTCTCCTTCCTCAGCCTCCCGAGTAGCTGGGATTACAGGC +ATGCGCCACCACACCTGGTTAATTTTTGTATTTTTAGTAGAGACGGGGTTTCACCATGTT +GGCCAGGCTGGTTGTGAATTTCTGATCTCAGGTGATCCGCCCGTCTGGGCCTCCCAGAGT +GCTGGATTGCAGGCTTGAGCCGCCACGTCTGGCCTCTTTTCTTTTTTCTTTGTTTTGAGA +CGGAGTCTCGCTTTGTCGCCCAGGCTGGAGTGCAGTGGCGCGATCTCGGCTCACTGCAAG +CTCTGCCTCCCTGATTCACGCCATTCTCCTGCCTCTGTCTCCCGAGTAGCTGGGACTACA +GGCGCCCGCTACAACGCCCGGCTAATTTTTTGTATTTTTTGGTAGAGACGGCATTTCACC +GTGTTAGCCGGAATGGTCTCGATCTCCTGACCTCGTGATCGCCCGCCTTGGCCTCCCAAA +GTGCTGGGATTACAGGCATGAGCCACCGCGCCCGGCCTCTTTTCTTTTTTAATTAGAGAC +GAGATCCTGCTCTGTCACCCAGGCCAGAGTGCAATGGCATCGTCTTAGCTCATTACAGCC +TCAACTTCCTGGGCTCAGGTGATTTCTTCCACCTCAGCCTCGCAAGTAGCTGGTACTAGA +GGCTTGTGCCACCACGCCCAGCTAATTTTTGTATTTTTTGTAGGGACGGGGTTTCACCGT +GTTGCCCAAGCTGGTCCTGAGCTCAAGCGATCTGCCCACCTGGGCCTACCAAAGTGCTAG +GATTACTGGCATGAATTACCATGCCTGGCCCAGAATAGTATATTGAGTGCCCATTTACTT +GCCACACAGTTTCAATGATTATCAGCTTGTGGCCAGACTTGTTTATCTCTATTTGCATCC +GCTCTCTGACTCCTTGATTATTTTAATGCAAGTCGCAGACCATAAATGATTTCATTCATA +AGTATTTGAGTATGTGGCCTGGCTCCTGCCCACTTCTCCATCCCCATCTGGTGCCACTGC +CCTTCTGGATTTCACTGGCACGGGGCAGGCAGGACTGGCTGATAAGTGCCCTGTCCCTCC +CTTCTAGGACAATAACGGTGTGATTGGACTGTTGGAGCCCATGAAGAAGAGCATGGTGCC +TGTGCAGGTGCAGCTGGATGTGCCTGTGGTAAAGGTGGCCTCAGGTGGGTCTGGGGGCAC +TTGCTCAGGGCAGGAGTTGGAGGACCTTGTTCTGGGGCTGGCCTAGCCTTGGGCCTTACA +GTTGTGGCCTGCATCCCTTACCTTTTCATCCTTAGGAAACGACCACTTGGTGATGCTGAC +AGCTGATGGTGACCTCTACACCTTGGGCTGCGGGGAACAGGGCCAGCTAGGCCGTGTGCC +TGAGTTATTTGCCAACCGTGGTGGCCGGCAAGGCCTCGGTAAGTGGCCTTGGTACCTCCA +GCAGGGCAAATTGGCAGGCCACCCCCACAGTGAAGGCCAAAGGCAGGAAGGATTTGCTGT +GGTCAGGCTTGCATCAGATGGGCTTGTGGTGTTGGTTAGGACTTTGGAGACAGACTGCTC +TGGTAGTTTTGCCACCTACTGTCTATGGGACTCTGAACATAGTTTCTTCATCACTAAGTC +TACCTACCTGTAAACCTACTTCATTAGGTTGCTGTGAAGTTAAATGAGTTAATGAGAAGA +ATATCAGGCAGATGGTAAGTTCCACGTAAATGATACCCGTAATGACTGTGGGAATCTGAG +CAAGGCACTTGTATTCTCTTGATCTCAGTTTCCTTTTCTATAAAATAGGGATAAGAGTCC +CTACTTAGCCTCTCAAGGGCTTTTATAATGGAGGAGAATTAAACTCGGGGCAGAGAGAAG +CCATGTGTGTCTGTCTGTCACTGACCGTGGCTTTCCCTTTGCCTGCAGAACGACTCCTGG +TCCCCAAGTGTGTGATGCTGAAATCCAGGGGAAGCCGGGGCCACGTGAGATTCCAGGATG +CCTTTTGTGGTGCCTATTTCACCTTTGCCATCTCCCATGAGGGCCACGTGTACGGCTTCG +GCCTCTCCAACTACCATCAGCTTGGTGAGCCCCGAGCCCAGCTTCAGGCATGACCCAGTG +GCCTGCGTTCCTGTCCTGGCTCTGCCACTCATTCATTGTGCATCCTTTGCGGGGTCGTCT +AACCCCTCCAAGCCAGTTTTGTCATCTGTAAAGTGAGAATGTCCATATCCTGATGGGAGG +TGGCCTCACTGTGGGAGGAGATTGAGAAGGGCAGCTCTCAGAACACCTTCACCCCTGATG +GCTCCGGCCTTTCCCCCAGGAACTCCGGGCACAGAATCTTGCTTCATACCCCAGAACCTA +ACATCCTTCAAGAATTCCACCAAGTCCTGGGTGGGCTTCTCTGGTGGCCAGCACCATACA +GTCTGCATGGATTCGGAAGGTAGGGCCTTTACGTCCTTCTCTAGTTTGGGGGTGGAGTGT +TCCCTGGCCTAGGCCTAGCCAGATTCCTGAGACCATGGTCCTTGGAGCCTGGGTCTGTTC +CATGGGTTGTACCATACATGGGTCCATGAGAGTCACTCTCATCCTCCTAGAGTCCTGGTG +TTCTTCCAAGTGTGAGTTCAATGGGGGCCCATGTAGATTCTCCTAGGCCTCCTCCAAAAC +TGGGAAGAGACACTGCAGATCTCCTTCTGATCGCTCTGGGAGCAGGGACACACTCCCATG +GACAGGTGGACTCACCTAGCCTGCCACCCATTTTGCCTGTAGCACGCCCTCTGCTATTGC +TCATCTCTCTCCCTCCTCCCATAGGAAAAGCATACAGCCTGGGCCGGGCTGAGTATGGGC +GGCTGGGCCTTGGAGAGGGTGCTGAGGAGAAGAGCATACCCACCCTCATCTCCAGGCTGC +CTGCTGTCTCCTCGGTGGCTTGTGGGGCCTCTGTGGGGTATGCTGTGACCAAGGATGGTG +AGTGGGGCTGCCTACACTCTGTCTAGTTGGGACCTGGGGGTCATGGTTCTTACCCAATTC +CCCAATAGGCTGTGATGTCCACTCTCGGGGGAGCCGAGGTACAGAGAGCAGTGTTTGTGA +TGGCACTTTGTTCCTGCTTCTCAGAAGCTCTGGCATTGATGAATATGAAATGAGTACACA +AATTATTTTAGTAAAGGTGACTTATTATGCAGAGGAGAGAAATAGCAAAGAGTGAGATAT +CACTGAGGCCTAAGGAGGCAATGGGACTGGAACCCAAGTCTCCAGACTCCTAACCCAGGC +TGCTCTCTCCCCTCAGGGTGACCCCTTCATATATCACCTTGTATGTTCCCGCTTTCCAGG +GACTTTTACTTAGAATCTAAATCAAGAAAAAAAAAGGCTTAGTAGTCAGAGTTGTAGCAA +CTATAGCAGAGGAGGGTGTGAACAAGTGACCACCAAAGCCTGAGTGGGTGAGGGGGATAG +CCATGGAGGTCCTGTAGAAGCCTGGAGCTGGCAGAGGTGCTTGACCTGAGGTTATCTGGG +AAGACTTCCTCAGGAAGTGGGGCTTGCACTGTACCTTGAAGGTTCCATTCCTTGTGAAAA +GCAAAGAATGCCATTCCAGGCAGAGGAACATCAGGGCAGTCTCAAAGGTGGCTGGTCCTG +GGAACAGAGGGTGGGGTAGGACCTTGAATGCCACGCCTAGGAGCAGCCTTTGGCAGTGTG +TAGGGACTGTGCTCTCTGGTTTACAGAGTTCTTTTTTATCCATCATCTCCTTGGGTTCTC +CCAACTTCCCTGAACTCCCAGAGTCTGGTACCTTGCCAAGCTGCTATTGGCCAAGGCCAC +AGTCCACGCCCATGTCCCAGGTTTCTCCTGCTACAGAAAGGTGGGCTGGGGATCCTGGAG +ACAGCTGTACCCATTTCTCTCTCTTGCAGGTCGTGTTTTCGCCTGGGGCATGGGCACCAA +CTACCAGCTGGGCACAGGGCAGGATGAGGACGCCTGGAGCCCTGTGGAGATGATGGGCAA +ACAGCTGGAGAACCGTGTGGTCTTATCTGTGTCCAGCGGGGGCCAGCATACAGTCTTATT +AGTCAAGGACAAAGAACAGAGCTGATGAAGCCTCTGAGGGCCTGGCTTCTGTCCTGCACA +ACCTCCCTCACAGAACAGGGAAGCAGTGACAGCTGCAGATGGCAGCGGGCCTCTCCCCAG +CCCTGAGCACTGTGTCAGTTCCTGCCTTTTCTCATCAGCAGAACAGAATCCTTTTCCTCT +TTTCCTTCCTCCTCTTTGGAATTTTCCTGGGACCTACAGAATAAAGGGGGGGATGGACAG +GGGGTTTTCAAAAGGAACATGGCTCACTCAGAGCTATATGGTTAGACGTTTCTCCCCTTT +TCCCTACCTTCCATGGTCCTGGTTGGCCCTGGCTTTGCCTACTAGAAAACCAAAACTTCC +CCCCTGGGGTTTTGTGCCCACTCTCTGAGAAGTTGGGGCTCCATCAAGCCCCATTCTAGT +CATGTGCCCCTTTCCTGTCCCTAACAGTCCACAGGCAAACAAATGGTACAGTCATAAGAG +CCATCTGTCACGGACCCACGCCCAGAGGAACGTGCAGAAAAAAGCAGAGCTACATGGCTG +TGGGCAACTATAAGCCAAATATTTGGCTCAGAACAGGTGTCCATGGGACAAAAAAGAACG +ATCCTCCACTTGACCAAGAAAAAAGTGATTCTCCCAGAAGCACAAAGCATACTCTTGCCC +CTCAGGTGTTGCTTGTGTACATCGTACCCATCCATTCGGCTTCACCTGCAGCCAACGGCC +TGGAATCGCAAAGAGACACCACTCTGGGCAGAGCAGAGCAGGGTATGGGGTGGGGAGAGA +GGGTGGAGGGTTTTATAAACAAACTTAACAGCAATATTGAAAGGAGGTGGGGGATTGAGG +GAGGGACAGAGTGTTGGAGGGCCAGAGACTAGTCCTGAGATGGAAACAGCAACTTGTACA +GTGGCTGAGAAAATAGGATATAGTTTTGATTTTTTTAATTGTAAAATATTTTGGAGGGAG +AACAAAATCTTTTAACATTTTGAATAAATTTAGAGTTTTATAAAATAGGCCACTTGTTTT +CTACACATTCCCTGCTTTTTAAGGGAGCACATATTATGTGCCAGGCACTGCTGGGAAAGA +CAGAATAAACTATAAACCTGGTGTTGAGGCTACAACTTAAGTGATGTCAAGATGTCCTGA +GGTGCCAACCAGCTGTCAGTGTGACTGTAACAAAGGCTTCAAATCTGTCAAGAAGTAAGG +AAAAGTTTTGTTTGAATTTTGTTTGGGTATTTCTGTTTTGGGAGTCACTGGATTATTTTT +AAATGCTGCATAGTACAATAGAGGCAGGGTGGATCTTTTAATACCAAACCAAAAAAAA diff --git a/test/csq/ENST00000373833/ENST00000373833.fa.fai b/test/csq/ENST00000373833/ENST00000373833.fa.fai new file mode 100644 index 0000000..f5acfc4 --- /dev/null +++ b/test/csq/ENST00000373833/ENST00000373833.fa.fai @@ -0,0 +1 @@ +1 33358 23 60 61 diff --git a/test/csq/ENST00000373833/ENST00000373833.gff b/test/csq/ENST00000373833/ENST00000373833.gff new file mode 100644 index 0000000..eb1eebf --- /dev/null +++ b/test/csq/ENST00000373833/ENST00000373833.gff @@ -0,0 +1,30 @@ +1 ensembl_havana gene 1 33358 . + . ID=gene:ENSG00000180198;Name=RCC1;biotype=protein_coding;description=regulator of chromosome condensation 1 [Source:HGNC Symbol%3BAcc:1913];gene_id=ENSG00000180198;logic_name=ensembl_havana_gene;version=11 +1 ensembl_havana transcript 115 33358 . + . ID=transcript:ENST00000373833;Parent=gene:ENSG00000180198;Name=RCC1-003;biotype=protein_coding;ccdsid=CCDS323.1;havana_transcript=OTTHUMT00000010323;havana_version=3;tag=basic;transcript_id=ENST00000373833;version=6 +1 ensembl_havana exon 115 142 . + . Parent=transcript:ENST00000373833;Name=ENSE00001935788;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001935788;rank=1;version=1 +1 ensembl_havana five_prime_UTR 115 142 . + . Parent=transcript:ENST00000373833 +1 ensembl_havana exon 2186 2218 . + . Parent=transcript:ENST00000373833;Name=ENSE00003478538;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003478538;rank=2;version=1 +1 ensembl_havana five_prime_UTR 2186 2218 . + . Parent=transcript:ENST00000373833 +1 ensembl_havana exon 2888 2959 . + . Parent=transcript:ENST00000373833;Name=ENSE00001273591;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001273591;rank=3;version=1 +1 ensembl_havana five_prime_UTR 2888 2959 . + . Parent=transcript:ENST00000373833 +1 ensembl_havana exon 10783 10925 . + . Parent=transcript:ENST00000373833;Name=ENSE00001273585;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001273585;rank=4;version=1 +1 ensembl_havana five_prime_UTR 10783 10925 . + . Parent=transcript:ENST00000373833 +1 ensembl_havana five_prime_UTR 23916 23924 . + . Parent=transcript:ENST00000373833 +1 ensembl_havana exon 23916 23997 . + . Parent=transcript:ENST00000373833;Name=ENSE00003621347;constitutive=0;ensembl_end_phase=1;ensembl_phase=-1;exon_id=ENSE00003621347;rank=5;version=1 +1 ensembl_havana CDS 23925 23997 . + 0 ID=CDS:ENSP00000362939;Parent=transcript:ENST00000373833;protein_id=ENSP00000362939 +1 ensembl_havana exon 25861 26048 . + . Parent=transcript:ENST00000373833;Name=ENSE00001273582;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00001273582;rank=6;version=1 +1 ensembl_havana CDS 25861 26048 . + 2 ID=CDS:ENSP00000362939;Parent=transcript:ENST00000373833;protein_id=ENSP00000362939 +1 ensembl_havana exon 26229 26408 . + . Parent=transcript:ENST00000373833;Name=ENSE00003695605;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003695605;rank=7;version=1 +1 ensembl_havana CDS 26229 26408 . + 0 ID=CDS:ENSP00000362939;Parent=transcript:ENST00000373833;protein_id=ENSP00000362939 +1 ensembl_havana exon 29108 29204 . + . Parent=transcript:ENST00000373833;Name=ENSE00003696436;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00003696436;rank=8;version=1 +1 ensembl_havana CDS 29108 29204 . + 0 ID=CDS:ENSP00000362939;Parent=transcript:ENST00000373833;protein_id=ENSP00000362939 +1 ensembl_havana exon 29316 29438 . + . Parent=transcript:ENST00000373833;Name=ENSE00003700481;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00003700481;rank=9;version=1 +1 ensembl_havana CDS 29316 29438 . + 2 ID=CDS:ENSP00000362939;Parent=transcript:ENST00000373833;protein_id=ENSP00000362939 +1 ensembl_havana exon 29929 30084 . + . Parent=transcript:ENST00000373833;Name=ENSE00003514701;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00003514701;rank=10;version=1 +1 ensembl_havana CDS 29929 30084 . + 2 ID=CDS:ENSP00000362939;Parent=transcript:ENST00000373833;protein_id=ENSP00000362939 +1 ensembl_havana exon 30320 30439 . + . Parent=transcript:ENST00000373833;Name=ENSE00001273554;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00001273554;rank=11;version=1 +1 ensembl_havana CDS 30320 30439 . + 2 ID=CDS:ENSP00000362939;Parent=transcript:ENST00000373833;protein_id=ENSP00000362939 +1 ensembl_havana exon 30805 30957 . + . Parent=transcript:ENST00000373833;Name=ENSE00003467600;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00003467600;rank=12;version=1 +1 ensembl_havana CDS 30805 30957 . + 2 ID=CDS:ENSP00000362939;Parent=transcript:ENST00000373833;protein_id=ENSP00000362939 +1 ensembl_havana CDS 31890 32065 . + 2 ID=CDS:ENSP00000362939;Parent=transcript:ENST00000373833;protein_id=ENSP00000362939 +1 ensembl_havana exon 31890 33358 . + . Parent=transcript:ENST00000373833;Name=ENSE00001828138;constitutive=0;ensembl_end_phase=-1;ensembl_phase=1;exon_id=ENSE00001828138;rank=13;version=2 +1 ensembl_havana three_prime_UTR 32066 33358 . + . Parent=transcript:ENST00000373833 diff --git a/test/csq/ENST00000373833/boundary-insertion.txt b/test/csq/ENST00000373833/boundary-insertion.txt new file mode 100644 index 0000000..f404449 --- /dev/null +++ b/test/csq/ENST00000373833/boundary-insertion.txt @@ -0,0 +1,3 @@ +33358 A ATT . +33358 A ATT . + diff --git a/test/csq/ENST00000373833/boundary-insertion.txt-l b/test/csq/ENST00000373833/boundary-insertion.txt-l new file mode 100644 index 0000000..f404449 --- /dev/null +++ b/test/csq/ENST00000373833/boundary-insertion.txt-l @@ -0,0 +1,3 @@ +33358 A ATT . +33358 A ATT . + diff --git a/test/csq/ENST00000373833/boundary-insertion.vcf b/test/csq/ENST00000373833/boundary-insertion.vcf new file mode 100644 index 0000000..aa3c399 --- /dev/null +++ b/test/csq/ENST00000373833/boundary-insertion.vcf @@ -0,0 +1,6 @@ +##fileformat=VCFv4.2 +##contig= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO +1 33358 . A ATT . . EXP=.;type=ENST00000373833:28865812-A-ATT just after exon diff --git a/test/csq/ENST00000375992/ENST00000375992.fa b/test/csq/ENST00000375992/ENST00000375992.fa new file mode 100644 index 0000000..2384725 --- /dev/null +++ b/test/csq/ENST00000375992/ENST00000375992.fa @@ -0,0 +1,112 @@ +>X X:51232843-51239468 +TACAAGTAAACTCTGAAGAATACTTTTTTCAATTTTTATTATGGAAAATTTCAAACATAT +ACAAAAGTATAGAGAATAGTATAATGAACTCTCAAACATCCATCACACAGCTTCAGCAAT +TACCAATTTATGGCCAATCTTGTTTCATCTATGTACTCAATTACCCCACACTCAGATGAT +TTTGAAGCGAATACCAGTAACATATCATTTCACCTGTACATTTTTCAGTATACTTCTCTA +AAAGATAATCATTTTTTAAAACAACATAACCACAGTACCATATCACATCTTAAAAAACAA +TAAATCAAGAAGTTATATTTTTATTTCAAATTATGTAACAACTGGGGACACAATCAATAC +ATTTCACTGGTATCATGAGGAAGAGTGTCACACTAAAATGGAGTCCAAGCTTTTATCGAT +GCAATTGCTTTATAATATAAAAGAAAAAATCAAACAAACTAGCATATTAGAACCACTTTT +GGTAATTTGTAAGGAGCTGAAGACTGCTGATATCACACATCCCATGGCAAACTCCGTAAG +ATTTCTTCTAAACATCTTTGTTATTTTCTTAAAATTGTTCTGGAGGCAGCTGATGCAAGT +CCTCTTTTTTAAAAAAACCTTCACTTTGTGTTCCCCTCTAATAGCAGCCTCTTTCCTAAA +TGCCTTTTCTAAATGACAACAATTTTGCCCTCTCTCAGCCCTCTGCATTCTCATATGCAG +AAACCAGGTAGGATGAGGAGCTAGCTGTGTGTACTGGAAAAGGGATGAAAACTACAGCCA +AATGGATCAGTGAGAGAGGCAAAAGAAATCTAGACAAACTAAATGGCATAATTAAGTTTG +GAAACTGCCTATGATATAGCCTGTTGGCTCTGGCATCAAATAATACAGTATGTTAAATCT +GTAAAATGAGGAAACAGTGTTTCCTCAAAGAGATGTTAAGATGACATGTAAGAAGTGGTT +AGGGCAGGCATTGCAAAAAAATGTCTTATATATCATTTTAAAATTTATTTTTATAAAAAC +TCACAACATTATTTTGCGTCCACTGTATTTATTTTTACAATTACCTTTATAGCAAGTGAT +AGTTTTTGAATAAAATTTAAGCAAATCATCAACAGTACAAAAACACTAGAGTTGTTACAC +GAAGGACTGATTCTACAAAACATTACCCTAGGTGATGGCATAATCTTAAAACTGTGCAGC +TACTGTGTGGTATGACATAGAAATAGGAGTAATAATTCTTGTCCTCAAACATCTTACAAC +TGTCTTGAAATATTTCTGAAACACCTGATACACAAAAGCCACACACATGGTGCCTAGATA +GCATATACTCTACTAGCACCAGATTGGAAGGGGAATGTTTTGCCACACGGTGATTACAAA +ATATTAATTGAATCAAAGAACCTTCAGTGATGCCAACCATATTTCAAGTAGTGTCTCAGA +TGCAGAATATGCAAAGAGTAAGGAAAAATAGTCTTTGCTCTCAAAGACATCATAGTCTAA +TGAAGGCAGACACATCAAAAAAGCACAACAAAAGGCTATAGGTGCTGAATTAAGAGTCTA +TTCACGTATAAGAGTACAACAACCAGAGCAAGAGTCAGTGGTATAGACAGGGAAGGAGTG +TCCCAAGATGCAGGAAGAAACCAGATGAGCTGTCTTCTTGGGAACACAGAAGTGCTCACC +TGTACTTGACAATTCCACTGATCACTGGGTTCACATCAATGTTTCTTTCAGCACAATACT +GAACATCTTTGCTGTTCATCTGGAAAAACAAACCAACACACAATTAGCAGGCTTATGTTA +ATAATTCCTCCAACTGACAAATGTACCAAGAGCTTATTATGTACATCAATCACTTTGCAT +CAAGCACTTCACTTCCACAGAATTATCTAATGCAGATGCAATCAATGAGTCTGGATCAGC +AACTGAGGGGTTATAAGCCAATGTATACCATGATGTAAAAAAGTCAGGAAAGCAGCGATA +TCAGAAGTTTTGTAAAAGAGGAGTGACCATTTAAGACATAAAATATCCTAAATTCCATGT +TACAGACTCTAGACTCATGGAAATAATTCAGGCTGATTCCCACCCACGAAAGAGTTTTCA +GTCCAGTGACCACATGGCCAAGAAAACAGATTAAGTACAATAAACTCTGCGAACCATGAC +ACAGAAGAGGGTTTCTTAACCCAGGTGGTCAGGAAAGGCTTCTCATTGGAGATGTTTGTA +AAGTGTCTATTTTTACTATCTCCAACAACAGATTTTTTTTTTAAACTGAGCGTCAGATAG +TTAGATAACTTGGCTTAAGTTTCAGTGAGGAAGAACTGGAACTAGATCTGTCTGACTTCA +AACCCCCAATGTAGTTTCTATCACATCATGCGCTCACTCTTTTTTTTTTTTTTTGAGACG +TAGTCTCACTCTGTCGCCCAGGCTGGAGTGATCTTGGCTCACTGCAACCTCTGCCTCCTG +GTTTCACGAGATTGTCCTGCTTCAACCTCCCAAATAGAAGGTATTACAGGCACGTGCCAC +CATGCCTGGCTGATTTTTGTAGTTTTACTTCATTAATAATTAGAAGTAGAGTTGGGGTTT +CGCCATATTGGCCAGGCTGGTCTCCAACTCCTGACCTCAAGTGATCTGCCCACCTCGACC +TCCCAAAGTACTGGGATTACAGGTGTGAGCCACCATGCCCAGCCCATGCTCTCTTATTCT +TATAAAAGTGTTATGTTTTAGCACAGTCAGCATAGTAACTTCCACTTCTTATAGTGCTGT +TTGCCCAAACATATTTAAAATCTGCTAAATACCATTAGTATTAATAGCTATCTTATCAAG +AGACCACTACCAGGAAAATATTGTTTAAAGTCTTTCAGAGAGTACCTGGTGGCTCCCCCA +CAAGGGAATTCTAGAGGTGAAAGCTCTGCCAGGCAAATACACATTTTCTAACTGTAAACA +AATTGGCATTCTTATACTAACCTTCTGAAATGAAATCACAGAAAGAATTTAAAACCTTTA +CATCAATTGTTGCAAATGAATCTATGCAAATAAAGCAACAAAATTATTTTCGAGTTTCTT +CCCTTTAGTTTGTTTCTTTAAAGTGTAGTCAACAGATTTTGTATCTAAACACACACATAC +TTCTTGAGAAAAACTGTATATATTATAGACACAGCACCAATTGTTTCCAGTATATGCATC +TATATTAATGTTTCCTCTTTATATATTCACAAGAATAAAACACTTGACCAGCTGAAAATG +TAAGCTATTTATAAAACATGCAGAAAATAAATCTGATTCATGTCTGCAAACCTCAATTGT +CTGTGTACTCTTTTTCCTTTCTTTATCAAGACAGGGCTGTAAAATTTAGGTGTACATTTT +TCTGCTATCACAAAAGAAATAATGTACAAGTGAACTCTACTACTCTTAGAAGGAAAAAAA +TCTCAACTATACATCAAATTTTGGAGCACTGAAGTGGCAGAAATTTTCTATATACTACCT +CTGTTCTAAAGAAATGTGGTGCCACTGTTCCGAAAACAAATCTTATAACACATTTAAGTA +TAGGTAAACAAAGTACAAATCTCAGTTTTTCAAAACATTTTCTGTACTAATGCTTTTAAC +TTGAAACTCTTGACTTAGTTTTGAAGAGAAAAAAAGAATCTCCTTGGCGCTCTTAACTAT +TCTGATGAGACTAAGTTCCAGAGAATATTTTACAAAAACTACTTAATTTAACAGTACGCC +TTGAAAAGTAACACTACATATTCTAAGTGTTTCTGGAAAAAAAAAAAGAAAAGGAAAAAC +CACGACATATTTATAAGCTAACAATTCTTAAGAGAGGGTTACTATGAATGCTGTACATTA +ATTTTTACTTTGTCAGATACATAACTTAAGAACCAAATAAGATGATGCATAATTACTTCT +AATGATAGAAAGTACGAGTTAAGTCTCCAAAGTAATCGTGACAGTGTTTCATGTGGAACA +CATTTCATCTACAAAAATATCCATAAAATACAATCTAGTATACCTCCTAGGTCAATATTA +ATGTAGAAACAAGAACCTTCTGTAATAATTAGGTTATTGAGGAAAATCTTAAGATCCATT +TTAGACTGAATAATTAAGTCAAATTGTTTGGAATTTAAAATATGTGCTTCATGATGATGA +AATAATCTGTACAACAAATAACCATGACATAAGTTTACCTGCGGAACAAATCTGCACTTG +TACCCCTGGAATTAAAAGTTACAAAATATTTTTTAAAATATGTGGTTCAAATATATATAT +TCAACATGTATCACTTTGTTAAGAGAAAAATAGAAAAATACTCCGTATTTGATCAGACCA +TGTAATTCAGATAATAAAACTGTTGTAAGTTTTAAAAAGCCACAATTTCTAGTTTACTCT +TTCCTTTGATAGCATTAGTGCAGAAAATATTTTGAGAAACAGATTTGTACTTTGTTTACC +TATACTTAAATGTGTTGTTGTAATATTTCTTTTCAAAACAGTGGCACCATATTTCTTTAG +AAAGTGCAACGGCACTCACTGTTTAGCAGCATAAAAAATATTATTTGTGAAATTACAATG +TACTCCAAATAGAGAAAAATATTTCAGTGTTTTGAAGGGTAAAATACAAAAAGCACACAA +GGGGGCAGCAAAAAAAAAAAACAGCAGAGACGGTTTCAAAAGGAACTTTTCTATGGTATT +AAAAGACAGGAGAGCAAAATAATGAGTAGGAGGTTTTTGGATTACAGGCAACGTTAAGTT +CTTGATGTAGATGCTGGTCACCTGCACCTAGAATAGGGTGTCCTGTGAGACAAAACAATT +ATTCTCTATCGTTAAGAGAGATTGTTCAGGAATCCTAATAGTTTGACAATTCTGTACCAG +CTGAACATCACTAGAGCTAACTCAGTTGGGATGTAATCACCATAAAAGATTCCATTCCTG +TGGTTACTGGGAGTCAGGGAGGTTTAAGCGGAATGTCACTACATTCAAATATGGGAGGGA +GACCACTTTCAAAAACGAACTTAAATCCAGAGAACCATGGTTCTTCTATGGTATCCAGTA +AGGGGCAATGGGAGTTGGAAGTTGAGTATGGGAAATCAAATTCTGTGAATACGGTTTTTC +TGATAAGATGTGTTTGGCTAGCAGATCCTCCGCAGCATCTATTCAATAAGGTTAATCTAC +ATGGGAAATAGCCATTTGAAGTCAGCAGTGAAAAATTACCACTTGTGAAAATTTTTTGAA +AACCAAATGATCTACATATAGAAACAGAAAAAGAAATTTCTGAAAGGGGCAAATGAGATC +CCATTTCAGAAGCTAAAGTGACTGTAGAGTGCAGAAAGAGCACAACATGTAGGATTTCCC +AATTTTTAAAAAAATTCAAAACTGATCTTTTAAACCAACTCCCACCACAGAAGGCCTCCC +TGACAACAAGGGCGAACGCTGTGAAGGAGAAAACTAAAGGGGAAAAAGAATACTAAAAGA +TGCCACACAACCAAGCTGGTCAGACTTTAAAGGCCTCCACTACCAAACAAACCACAAGGC +TGGTATCAAAAATGCGCACGCACGCTCACCCACGAATATGTGTGAAATATAAAAGAACCA +AAAACATCACAGGGCGCACAGGCAGACACACACTCCACACACAATCCCCACCCACCCCTC +GCCCCCCACACACACCTCCCAAAAGCAGGGTGAACAGTTAAGGCACCTAAAACCCCAAGC +CGCATAGGCTTCCCCGAAACATTTTACAGTGTAACCAAGAAGCGATTTTGAAAGCATCTG +AAAAACGTGCAAACTGTCTTGAAAACAGGGCCTGGCAACTGAGACAGTTTGCAAGCGTGA +TTCAGAGGGTCTGCCAAGGAAACAAAAGAAGCCTCCCTCCTCCCCGTGAGACCGCACATG +GCACGAGAGGTGCTCCAGGCGGGACGCATTTTAAGCGAGGCAGACAAATAGAAGTCTGCG +CGAGCGCAAGCGGTACATACTAGGGATCGCTATCTGGCGAGGATGGGGCCATGGAGTTTC +CATTGGTTGGGGAACCGCCCAGCTTTAGTTTCTCCAGATATTCGGCGTGCACGGGCTTGT +GGCACTGGAGAACCTTGATGGCATCTTCGACTTTGAACCACTCTCGCTTCCTCCCAATGC +TAACCGAATCTTCCCAATCCTCCAGCAGCTCCGTGACAGTCAGTACATACACGTACGTTC +TGTGCTTGCGATCCTGGTTCTGTTCGAAGACGCCCAGGAGCCGGCCTAACTTCCCCTTGA +CTCCCGCTTCTTCGTACACCTCTCGGACCGCCGCACCGCCCGGCTCCTCCTCGGGCTCCA +TGCCCCCGCCCGGCACGATCCAGCGGTCCGGGTACCGGCTGCTACTCACTAACAGGACCT +CGTCCTCGCGTTCGCTCCGGAAGCACAGGCACGCCGCCCGCTTCTTGAACCCCTCGGGGT +CGTAGGTCCGCGTCTGGTTGGGTTTGCACTTCATCCTCGAGGCAGCCTCCTCGAGGCAGC +CTCCTCTCGCCTCTCGCTGCTGTGTGGGCCGCCGCTGCCGCTGCCGCCGCCGGGGAACAG +CCGAGGTGCTGGGAAGAGAAAGGGCCGAGGCGAGGGGCGGGGAAAGAGAGGCGCCTCCGT +CTGCCCGCGAGCCCGGGGAGCGGAGG diff --git a/test/csq/ENST00000375992/ENST00000375992.fa.fai b/test/csq/ENST00000375992/ENST00000375992.fa.fai new file mode 100644 index 0000000..d34962f --- /dev/null +++ b/test/csq/ENST00000375992/ENST00000375992.fa.fai @@ -0,0 +1 @@ +X 6626 23 60 61 diff --git a/test/csq/ENST00000375992/ENST00000375992.gff b/test/csq/ENST00000375992/ENST00000375992.gff new file mode 100644 index 0000000..3c30bcf --- /dev/null +++ b/test/csq/ENST00000375992/ENST00000375992.gff @@ -0,0 +1,8 @@ +X ensembl_havana gene 21 6606 . - . ID=gene:ENSG00000196368;Name=NUDT11;biotype=protein_coding;description=nudix (nucleoside diphosphate linked moiety X)-type motif 11 [Source:HGNC Symbol%3BAcc:18011];gene_id=ENSG00000196368;logic_name=ensembl_havana_gene;version=4 +X ensembl_havana transcript 21 6606 . - . ID=transcript:ENST00000375992;Parent=gene:ENSG00000196368;Name=NUDT11-001;biotype=protein_coding;ccdsid=CCDS43952.1;havana_transcript=OTTHUMT00000056579;havana_version=1;tag=basic;transcript_id=ENST00000375992;version=3 +X ensembl_havana three_prime_UTR 21 1758 . - . Parent=transcript:ENST00000375992 +X ensembl_havana exon 21 1759 . - . Parent=transcript:ENST00000375992;Name=ENSE00001469078;constitutive=1;ensembl_end_phase=-1;ensembl_phase=2;exon_id=ENSE00001469078;rank=2;version=3 +X ensembl_havana CDS 1759 1759 . - 1 ID=CDS:ENSP00000365160;Parent=transcript:ENST00000375992;protein_id=ENSP00000365160 +X ensembl_havana CDS 5961 6454 . - 0 ID=CDS:ENSP00000365160;Parent=transcript:ENST00000375992;protein_id=ENSP00000365160 +X ensembl_havana exon 5961 6606 . - . Parent=transcript:ENST00000375992;Name=ENSE00001469091;constitutive=1;ensembl_end_phase=2;ensembl_phase=-1;exon_id=ENSE00001469091;rank=1;version=3 +X ensembl_havana five_prime_UTR 6455 6606 . - . Parent=transcript:ENST00000375992 diff --git a/test/csq/ENST00000375992/incorrect-synon-del-not-start-lost.txt b/test/csq/ENST00000375992/incorrect-synon-del-not-start-lost.txt new file mode 100644 index 0000000..00f495b --- /dev/null +++ b/test/csq/ENST00000375992/incorrect-synon-del-not-start-lost.txt @@ -0,0 +1,3 @@ +6453 ATCCTCGAGGCAGCC A 5_prime_utr|NUDT11|ENST00000375992|protein_coding,start_lost|NUDT11|ENST00000375992|protein_coding|- +6453 ATCCTCGAGGCAGCC A 5_prime_utr|NUDT11|ENST00000375992|protein_coding,start_lost|NUDT11|ENST00000375992|protein_coding|- + diff --git a/test/csq/ENST00000375992/incorrect-synon-del-not-start-lost.vcf b/test/csq/ENST00000375992/incorrect-synon-del-not-start-lost.vcf new file mode 100644 index 0000000..7653a01 --- /dev/null +++ b/test/csq/ENST00000375992/incorrect-synon-del-not-start-lost.vcf @@ -0,0 +1,7 @@ +##fileformat=VCFv4.2 +##contig= +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO +X 6453 . ATCCTCGAGGCAGCC A . . EXP=5_prime_utr|NUDT11|ENST00000375992|protein_coding,start_lost|NUDT11|ENST00000375992|protein_coding|-;type=ENST00000375992:51239295-ATCCTCGAGGCAGCC-A, could be realigned if del moved to right diff --git a/test/csq/ENST00000378322/ENST00000378322.fa b/test/csq/ENST00000378322/ENST00000378322.fa new file mode 100644 index 0000000..c4c79d2 --- /dev/null +++ b/test/csq/ENST00000378322/ENST00000378322.fa @@ -0,0 +1,368 @@ +>1 1:3547331-3569325 +TAGTTGTATAAATCAGCAAGTATTTATTTTAAATAATAAAACTACAGTTTTATACCATAC +ATATTTACAAAAATGCTTTGCTATAGAAAAATAGAATCAATCACTGAATCCAGACCACCA +CAGTGGAGAACCTCCTGGTGAAGCTGTGTTTTTTCCCACACTGGAAACACAGAGTAGCCC +TGTTTCTGCACACGTTAGTGCACCGCTGCTACGTGTGGCCGCCCAGCTGTCTGCAGGCTG +TGCCGACCACTGCCTCTGTCTCCAGGAAGCAGAGGCAGAAGTGATCCTTGCTGAGGAGGG +CCATCGAGTCTCCGCTTAAATGCCAGCACAGAGAGAGCACTGCAAAGTCGCCTAGAGAGA +GACAGGTGGCCAGAGGATTACAGCAGGGGAGGCCCAGATTCTGGGGGATGGGCACCCCCT +TGTCCTGCAGGCCAGCACAGTGCCTGGAGTGACCCACATAGGCAGAGCCAGGGTGGAGCC +CCAGAGCTGCCTCAAGTCAGGGAGAGGCTGCTTCTAGCCCATAAAGCTGAGGGCAGCGGG +TCCCCTGTGTGTCCGTCTTGAGGTTTACGCAAAGACTCTGAGGGCAGTTTCCCTGGAGTG +CTGCCGGAGACAGCAGCTGGGCTTCAACAGTTCAGCCCGTGTGATGCCAGACTGCACACA +GCAAGGCTGCCACGTCCGTGGCCTCGGGGATGTGCTTACCTTCCCCAGGCACCTGCACCG +ACATGCAGCCCGCTGGGGACCACAGGTAGAGCCTGCTGCCTCCCGTGCAGATGGCCAGCC +GCGGCTGCTGCGGGTCCCACTGAAATGCGCGCACTGGGGACAGCTGCTCGAGCACCGCGA +ACAGCCTCAGCTTCTGAATGTCCCAGACCCAGACGGCATTGGGAATGTTGTCTGAGGAAG +GAAGGACAGGGCACCGGTGTCATCCCTGCCTGGCTCCTCTGTGTTGGCCCTGCCCCTCTG +CTCTGCTGTTGACACCACAGGAGGGGAGGGGAAGAACCGGTGGGGTGGGGCGGCTGCACC +CTGCAGTCTGGGTTCAGTTGGGCCCTGTAGGGCTCCTGGCCAGGGCCAGGGTGGCCATCA +CGGGCTGTAAGGGGCCCAAATGTGTTTCTTTCTTTGGTATTTTTTTTTTTTTTTTAGCCC +TTTACAAATGGAGAAACCCTTAACAAAAGGCGGGCTGCAGTGTGCCCAGCCCTGCTTTCT +ACTCAGCAGAGTGGAGCAAGTGAGCAGGGTGGAGGCCTCCTGACTCATGCGCGGACCTGC +GGCTGCTGCAGGACAAAGGCCCAGCGCCTCCAAGGAGCTTCTGTGAGCACCTCGGCTACT +GCAGAAACGTGAAAGGAGGTGACGTGTCGGAAACCCCCAACTTCATTTTCTTTTCCAGTC +GCTTCTACACCTGGGGCCACAGGACACAGTAAAGGGTGAGACAGCACCTGCGTCAGCACA +ACTGACCGTTCCTTGTCGCCAGGAAGTAGCTGTCAGGACTAAATGCCAGCATTCCTATGC +CGATTTTCGGGTTTGCTCTGTCGGTAACAGGTTTCAGTGTCTGTAAGGAGACTGGGACAG +AGGCGATCTCATCTAGAACACCAACAGGAAGAACACGCCATTGTCACCCTTTCGGGAAGT +ACGCACGCGGCTGAGAGGCTGCTGTGCCTGCATCGGGCATCGCGAACCCAGCTCCTCTGT +TCAAAGGGGAGGAAAGTGCGGCCCAAGGGCAGGAAGAGCTAAGCAAAGCCTGGCAGCCGC +AGCGAGGGGCCTGCCCGCAAGTGCCCCGGATGAGAGTGGCACCATCACCTGCCAGGCCCG +ACTAGGTGGGGGGTGGACCCCACGTGCCAGGGGCTGACTGGAGAGGGACATGGACAGGTC +CTAGCTGCAATCTCAGCAGCTCCAACTCCTCAGCACTTTTCTGTCGACTACCAGCATCTG +AGTTCACAATCCCTTCCACCTCAGCGTCAGTACCCTTAGACTTTCCGGCTGTGGAAGAAC +CATCATCACAGCAGAAGCAGGGGCTGTGGAACAAGGACGCCCCTGGGCTCCTGGGGAGCG +CCTCCTGTGTGCCAGGCTGCACCTGTCCTGACCCCCATCCTGAGCACACACCGAGCCCCG +GGGTGGGCCCGTCGGCACTTGGGGCACCGCTTCCTCTACCTGCAACCTTCAGATGCCCTC +ATGCCCCTGTGGGATGGGTGCTTTTACTATGCCCATTTCAGCGATGAGGAAACAGACACA +TAGGAAATGCCCAGAGTCAAGAGGCTGCATCAGAACCGGGCCTCAAGCCGGAGACAGCGC +TCGGGAGCACCGCCGGGTTCCAGACCCACTCTGAGCGCCACCCACGGAAAAGTGTTTCTT +TGAAAAACATCATTCTCGGAGCTCCGGAAAAACATCCCCTCGGAGCTCCCGCTGTCAGAT +CCGGGTCTCCAGGGCTCATATTCAGTAACAGAAGCCGCACCTTCACGGCCCACTGCGCAA +TTCAGACCCTAGTCAACCTCCAGCCAACAGGCTGAGGGGCACACTGGCTGGAAGCATGGA +AGGGAAAAAAAGTTTTTTTTTTTAAACATAAGGAACATCCGAAGTTTATCTGGACAACGA +GGAATCTTGCATTAAAAAAGGAAAACAAATGACATCACATGTGCTACTTACATTTACTCT +CTGAGCTCGGGAGAGGGCCGGCCCCGGCCCGGGGCGGCGGGAAGGAGAGGCAGCCCAGTC +CCAGCTGTGGGCTCTTCTCGGCCTCCTTATACACCACCTGAAAGACACAAGGTGGCCACG +CCCGGCTCAGGACAGGGACCCGGAAGCCAAGGATGGACGTGGCAAATGCCCATGACAGCG +CATGGTCAACAGGTGTGCCTGCCATGACAGCTGGTCCTGCTGCCACCGGGAGAGACGGAA +GCACGAACCCCGCAGTCCCGAGAGCTGAGATCACCCAGCCACCCTCTCTCGTGTCCTGCT +GAGGAGCCCACCCTTTGAGACACAGGCAGCAAATGTGTGCCCTGTGATTACAGACGGGAG +ACCACTGCAGCCACCATCATCCAGCAAGGGAGTGGGCTCAGCCTTCCCTCCGTGATAAGA +GGATACAGAGAACACTTGCACCAACACAGCAGAGGCCCCGGGAGCAGCAGACACAGACCC +GAGGTGGGGGCATCTGTGCCCGAGAGCCTGGCAAGCAAAGGACAGCGGCCCAGGCTCAGT +GGAAGGCGGGCAGCCCCTACGCCCCTGAAGAGCCCCAGGTAAGGGAGTCACCTGGCCTGG +TTCATGCCTTTAAAGCATGCTCTGCTGCTGTGTGGCGAAGGGATTTGGAGAATGCAGGAA +TCACAGGCAAACCTTCAGGACCTGTGTGGCCAGCCCTGCTCGGGCTCACCTGTCCAGACA +CCCTGGCCTCCAGCCACACAAGCCACTGGCCACGTCAGGAGGCCCCTCTGCCTGAAACAC +CCTTTCTGCCCAGACACCGCGCAGCTCCTCCTCCTGGTCTTCACTTAAACACCCCTCCAG +GATGCATCCCCGGCAGTGGCTGATCTGGCATGCGCAGCCCCAGCCACTCACTGGCCTCTT +CATCGAATCCAAGCCGCCTTTCACTCAGCTCTGTCGGTTACAGGTCAACACCAGGAGGGC +AGCATTTGTCTCTGGCTCCCAGCGCAGTGCCCGCTGCACACATGGATGCGTGGCCCACTC +CTCGGGGCCTTTGCATTTCCTGTTCCCTTGGCCTGGAACGCTCCCTCCCCGAGTCCCTGA +TCACTGGTGCAGCATCTGTGCCTGCGATCCCTCGCTGGTGGCCACTCCCTGCCACCCCGT +GGAGACACCCAGCTCTCCAGCCCCTTCCCTGTCTCTCCAGCCGCACTCTGCAAGTGCAGG +GGTCTGTCTCTTCTTCTCTGGCTGCGGCCCAGAGCACAGTGCCTGGCACGACAGCAGATG +CCCAGTGTTTGGGGGCAGGAGACCCTGGCCACTCTGTACAGCACAGGGATCTGCATCCAG +ACAGACCACAAAGGAGAAAACTGGACTGGGGTGGCAGCGGCAGAGGACAGGCCAGGGCAA +GGCCCACTTCAGACCCTTTGGGCAGCGTGGAGGAGGAAGAACAAAGGCCAGGGCAGGGCC +AGACGCGTGAAATGTCACAGTAGCAAGTTTACGGTGATGGAAGTGCCCGGTTAAATAATA +AACCACAATCAAGAAAGCAAAGTGAAGGAGCAGTTTCCCACCGCCCTCCCCAACAGCCTG +CTCAGGCAGAAACACGTGTTCCAGACTTACTATCTTGGGATCATTAATGGCTGCAGGATG +CCCAAACTCCGTGATCATTTTCCAAGTCACGTGATTAAGGATGCGCACCTGAGGAAGGAA +ACCATGCACAGGTGAGGCAGGGCCCGGCCCGCTGGGCGGTCGGACTTCCTGAGTGCCCTG +CACTGGTTCCCACCTTTCCATCATAGCTCCCAACTGCCAGGAACTGACTGCTGGGGCTCC +AGGCCACAGACTTGATGCCCAGGGACCACTCGTAAGCGCTGTACGTGGACAACAACCGGC +CATCCAATGAGTACAGCAGAATCTTGTACTGCAGATGAGACATTTCAGTTAATAATGAAT +ACACCCCCGTCGCCAGGAACACACCACAGACGCGGGTGCTGCAGAGTGACATTGGTGCAG +ATAGCACAAAGCTGGCAGGACTGTCCGCGTGGCCGTGGAAAAGCTGGAACTGCCAGCTAG +TACTGAGATAGTCACGGAGAGGCAGTGAGAGCATGAGGAAAAAGGGGAAATTGGGAGGTC +AACCTAATGGCTCGCTGATAAAAGTTCAACTCGGCCGGGCACTGTGGCTCACGCCTGTAA +TCCCAGCACTTTGGGAGGCCGAAGCTGGCAGATCACTTGAACACAGAAGTTCAAGAGCAG +TCTGGGCAACACGGTGAAACCCCATCTCTACAAAGAATACAAAAATTAGCCGGGCGTGGT +GGTGCATGCTTGTGGTCCCAGCTACTTGGGAGGCTGAGGTAGGAGGATCACTTGAGTCCA +GGAGGTCGAGGCTGCAGTGGGCCGTGATCACACCACTGCACTCCAGCCTGGGTGACAGAG +CAAGACCCTGTCTTTTAAAACAAAGCTCAACTTGTTATCTGAAATAAGATAAAGCAAACT +ATATTGCAGCATTCAGAAAGCATGAAATTCCGGGAAAAGCTCTCGAAAGCAAACATGTCA +CCTGGTCATCTTCATACCTCCAAGCAGGTGTCCCACACTGCCAGCACACAGCCGTTTGGG +GCCCACTCAATCCCTGTGAGATCCTGGGTGTCCGTATCAAAATGCTTCCAAAGGAAGGGG +GGGAAACATTAAATTTGGAAAATATTTTCGTAAATAAATAATTGCATTTATGACTGATGT +TCTTAACGCACTTAATTTCCTTATATAGAAATTGACAAAATCTCAACAGCTCTATCCTGG +AAATGCATGAAATCCCTGTAGAGCTGCTGCTGGGGCTGCACCGCCACAGATGCCAGCGTC +AGTGCCTGGCCAGCCCCCAAGGGCGGCTTGGTCTCCCCGCGCCTGCACTCGTGTGCACAC +TCTCCCCCTCACCTTTCCTTGCCTGGCCAGCCCCCGAGGGCGGCTTGGTCTCCCCGCGCC +TGCACTCGTGTGCACACTCTCCCCCTCACCTTTCCTTGCCTGGCCAGCCCCCGAAGGTGG +CTTGGTCTCCCCGCACCTGCACTCATGTGCACACTCTCCCCCTCACCTTTCCTTGCCTGG +CCAGGCTCACTCCTTTAGACCCAGCTCAGACAAGTCCCTTCCAGAGCACTGCCTGGATCC +CGGGTTCTGCACTCTGACAGCATTCCAGAGGTTGCTCTACCTTAATGATGGATTGTGCTG +GAATCGTGTTCATATGTCTGCTGTGGGGGCAGTGCCCTCTGTGCCTGGGCACCTGGCAGA +GCGCCCTGCCTAATGCAGGCCCTCAGTCAAGGTGAACTTCCACGTCCCCCCAACTCCCGA +CGTGGCACACACATGCGCAAACACCATCACACAGGACAAGGAAAAGGGCTCAAATGTGAC +AGCATATTCACTTTTAAAACACCTGGGCACGCGTCCTTTTCACCAAGTCTCCTGAACACA +CAACCGGGTGCCACTGGAAGTGATTCGCAGCGCACCTGCCCTTTGTTAATACAACATCAC +CTTGCTCCATATCCTACCAAAGATCCCCTGGAATCTGGAAGGATCTACTTCACTCGATCC +CTCCACAGTCAGCAGGACAACTTTATTCCAGTCTGGGGGACGCCTTACCCGCAGGAGCTG +CCAATCACTGCAGACGAAGATGCTCACGTAATCTTTGCAGTCGCGCCGTTCTGCCAGCGC +CATGTAGCGGCCGTCCCTGGTGAAGGTGATTCCTGTGGGAAGAGGCAAATGCACTGAAAT +CAAGCGGCCACAAAATCAAGCAAGAGAAACCACAGTAGTAATTCACAAGGAAGGAGGAGG +AAAAGAAAGCAGAGGTGAAAAGAAGGGAAATGGCACAATGCCGAGCACTGCTCCTCAGAC +AGACAAGAACATTCTAGCGCAGAGGAGAAACCCAAGGCACGGTGCCTTCACCCTCACAAC +GCAGTGTGTGCTGGGGGAAGCTGTACACACACAGGAGCCGGTTTGCAAGGCTCTGTCAAA +AATACCAAGTGATGTGACCTCTGATTAATCACAAATATGAGTGAGAAACACAGGCCTTCG +AGTCCCCCCATGTCTAAGCTGCGGGACACCCAGGGCTATCTCCAGCTAGGCAAAAGGCAG +CTGGTTCCTACCATATTTATTTTACCTTTGAATTTAATTATTTGGAAGAAGTAAACTGAA +GATGAAAATGTGTGGCCAGGCATGGTGGCTCACGCCTGTAATCCCGGCACTTTGGGAGGC +TGAAGCAGGTGAATCGCTTGAGCCTAGGAATTTGAAAGGAGCCCAGACAACTTGGTGAAA +CCCCATCTCTACAAAATATCAGCCGGCTGTGATGGTGTGTGCCTGTAGTCCCAGCTACTC +AGGAGGCTGAGGTGAGAGGATCACTTAAGCCCAGGAGGTCGAGGCTGCACTGAGCTGTGA +TCGTGTCACTGCACTCCAGCCTGGGTGACAGAGCAAGACCCTGTCTCAAAAAAGTAATAA +TAAGATGAAAATGTGGAAGAAACTTTAGTTGAAAATGTTAAACTCTTATTTTCCAGTTCT +GTATTAGCTTAAAAAGCCCTAGGCCAGAATTCATCATTCCTGAGTGAAAAGAATACCTCA +AATGACGAAACCACGGTGTCCACTCCTATCAAGAGATATGTATCTCATCTGGAGGGACGC +TAATATTCCAACTATAAGAATAAGAGTGTGACTGCATTGCATTCAAATGCAATTTCCAAA +CCGCTGGCAGCAACAGAGAAAAATGAAAGCATCATTCCAACTGTGTATGTTTCATTCCGC +AAAAAGACAGTGCGGTGTCGTCCAGGACTCAGGAGTGGCACCTCCCACTAGCTCTGCGCG +GTCCAGTTAGACGCGCTGGCAGTGGGCCACCCTGCGCCGGCCCCCTTTCTTCCAGATGGC +TCACAGGCTTCCACAAGGAAGGGACACTGGTCACATATCCCTCTGGGATGCCCAGAGATG +ACAGGCAAGACCTCCCCCTTTCGCAGACATCATATTTAGTCCACAGAAGAGAGAAAGCTC +AGAACTGGATGCCTGAGGTGGGCCTCTCAACAGGCATCGGCTGGAAGGGGTCTGAACGCC +CAGCTCTGCCGCCAAGGTCAAGGGGACCGGCATCAACGCCACCGTTCTTCCATGTCTTAG +GCCACGTTGTCTTGAGTCACTGTGGTCATGTTTTAAAAGGGGACTCTTGCCTTTTTGAGA +CACATATGGAAATATTTACAGATGAAGTATGAGGAGACCTAAGGTCTCCTTTAAAAGAGC +CCAAGGGGGTTGGCTATGTGTTGATATGCTGCTGAAGCTACTTCTGCCTCTTTGAAACTT +CCCGTGACAAAAAAGTCAAACAGCTGCAAAGAAATGGCTTTTGCGTGGCTCCGATCGACT +CACCCTGCAGACAAGCTTTCGGGTATTTGATGTAAGACACGGATTTTGTGCACAAGGACC +AGACGGTTATCCGCAGCTGTTGGGGGAAAGGGGAAAGAGAAAGGAAACACTTCTTTAGCA +TCATCAGAGACCGTCTCAATCCTCAACCCGCCCACGCGTCCCCAAGCACAGGCCTGACTG +CTGGAGTGGATCTATCAGGACCTGGGGGATGCCTGCCCTCCTACCGGAATATTCAAATGC +GTATTTTACTGTGGTTACGGTAAATTTGGTGTTCTTGGTTTTCTGTTGTTGTTGTTTTAT +ACCAAAATTGAGTGACACAAAGTTAAATCCAAGTGCTTTTTCATTAGCTTTTTCAAAGTG +ACCATAGGTTGCATGTTATAATAACCCTGAGTTACTCAGAGAAAAATCTTGATCTAGAAA +CCACCACGGGTTCAGTCTCCTTTATGGGAAGACAGAGGATCTGGAGATTGGATGCAGCCA +CTCCGGGACTCACCAGGGGGCTGTGAGCCTGCATCTGCAGCCCTGAGGCAGGAGCAGCCA +CTCAACACCCAAGAAGGTGTCCGTCTGCCTCCTGCGTGTGCTCGCTGGCCTGGCTGCATC +TGCAGAGGGTTCTAGAACATGCGCTGCTGGACTGTCCACTTTTCCACCCCTTTCCCTGAC +TCAGGGAGCTGAGAGCTGACTAGGCTGGCACAGTGAGGCCAAAAGATGATTTTCTAACCA +GGCCGACGAGGGCGTGCCTGCTGAGGGAGAGGCACCGCAGTGGGTGGTCCAGCCCTCCCC +GTGGCAGCGCCGCGGGACTTCCAGGGCTGCTGTGTCCCTCCACCTGCATTTCCCACTGAG +ACCCCGTGGAGCCTACCAGGGAATCATCTTGCTTCCCACATCCCCGGCCCACTGATGAAT +CTGGTAGTTAACTGAAATATGGCCGAGGTGCGGGGACACAAGGTGCGGGGTGGGGTGCTG +ACTGCCAGCTCCGTGTGTGGGGACACAGGGCTGCGCAGCTCCATGTGGGGTGGGGTGCTG +ACTGCCAGCTCCGTGTGTGGGGACACAGGGCTGCGCAGCTCCATGCGGGGTGGGGTGCTG +ACTGCCAGCTCCGTGTGTGTCAGGCAGGGGTCCTCGCTGAGGATGAGGCCCGGGGTGGGG +GACCGTCTCCAGCAGCGTAAGTGGGGCCGCAGCGTGTGGGGCACAGCATGTCCACAGTGT +CACTCCTGCAAACGCTGCCAGGTTGTCAGTATAGGATATTAACAAATGATTTAATTTAAA +TGTCTACGCATCATCTCTTCTTACAACAGAAAAGAAAATCTGATGTCTGTAATTGTTTCT +CCAAACAACATATACAGCGTTCAGGAGAGAAGTCCTGAACACACAGGTAGTGGATCAACG +AGCTCCAGGGGTCACGTGGCAGCACGGAAGGGCTCCTGTGCTGATGCTGAACCCGAAACA +CACTGGCCGTTCTGGGGACCATGCCTCGGAACTCCAGCTGCACAGAGCACTTGCTCCTCT +AACAGCTCCACAAGCTGAGGCCAAGGAGGGCGCTGGGGCCTGAGCGAGGAAGCGTGCTAC +TTCCCACCAGCGTGTCTGAGGCTGAAACCTTGCCCAAGCCTCTCAGACTCAGCAGGGTGG +GTGCAGCGCCTGAGGCTCTGAGCATCAGCAGGGCGGGGTGGAGCGCCCGAGCATCTCAGC +ATCAGCAGGGCGGGGTGGAGCGCCCGAGGCTCTGAGCATCAGCAGGGCAGGGTGGAACAC +CCGAGGCTCTGAGCATCAGCAGGGCGGGGTGCAGCGCCCGAGGCTCTGAGCATCAGCAGG +GCGGGGTGCAGCGCCCGAGGCTCTGAGCATCAGCAGGGCAGGGTGGAACGCCCCAGGCTC +TGAGCGTCAGCAGGGCGGGGTGGAGCGCCCGAGGCTCTGAGCATCAGCAGGGCAGGGTGG +AGCGCCCGAGCATCTCAGCATCAGCAGGGCAGGGTGCAGCAACGGAGCATCTCAGCATCA +GCAGGGCGGGGTGGAGCACCCAAGCATCTCAGCATCAGCAGGGCGGGGTGCAGCGCCCGA +GCCTCTCAGCATCAGGAGAGTCCATGTGCCACCCAGGGCAGAGACCTGCCCTCCAGAGCC +TACTGCAGAGTCACAGGAGAAAAGCACATCTCCCACCTGTGGCCCTGCATCCCTGTGGGG +TGCGCCTGGCCGAGGCTCCCCACTCAGGCACATCTTAGGAAACACAGGGAGCACTTTAAG +CCTGATTTTTACCTTCATCTCACAAAAACAAAGAAACAAAAACCTTTAAAAGATAACTTT +GCAACTTTTAAAAACCCAATAAGAAAAAAAGGTAGTTAAATATACACCTTCATCAGCGCT +GTTACCTTCCACTGACCACTGGAGAAGCCAGCGGAGGAGACCCGTGGGATGGGCTCCACA +GCACTCAGCAGCAGGAAGAAAGGACCAGAGGGATCCACATGACCCAGAGCACTCAGGAGG +GAAGGAAGGGGCCGCTGATCCACGCTACGACCCAGTGTGCTGAAGACGGAAGGAACGGGC +CACCGATCCACACCACAACTCAGCATGCTCAGGGTGAGAGGAATGGGCCACGGATCCAAG +CCATGACCCAGTACACTCAAGACGGGAGGAACAGGCCACTGATCCATGCCACGACCCAGC +ACTCTCTCCACACCATGACCCAGCACTCTCAAGATGGAGGAACGGGCCACTGATCCACCC +CACAACCCAGCACACTCAAAACCAGCAAGATGCCAGGGAAAAGGAAGCAGACGCACAGCT +CCACGCACCATGGCTCTGTGCAGATGGGATTCCGAGTAGGCAGTGCTGCTCGCCCCGCAG +CAGGCACCGGCTGCCGGACACAGGTGGGAGACGGACTGAGCACAAGGGGCACGAGGAGCC +CCATGCCACGGGCGAACAGTCTTGGTCCTGATTGTGGCGGCAATGACGTGCAAAGTGACT +CACTCAACTGTGCTCTTAAAGTGGGTGAATTCTCTTGCTTATAAATTGTTTTAATTGCCT +TTATTCAGATATAAGAAAAAGTCTGCAGTCTGGATATATTTTTAAAGCTAACTATAGACT +ATTTACAACATACACACTCAAGTTTAAGGATGCAGAAATGTAGAAGGTAAAAGGATAGAA +AAAGACATATCAAGAAAATCCTAACCAAGAGAAAGGTGGCACTGCCGCATTCGTACGGGA +TAAATCAGACTCTGAAACAAAAAGAACCGTGAGACATAAAGAGGAATACTTTACAACAAA +AGGCCTGTGCCACCGCGGAATCATGGGAACCGCTTCACTAGGAAATCTGTTTACAAACAG +TTAAAAGTTTGTATGCAGCTAACAACAAAGTCTCAAAAATACATTTAAAAATCTGGCAGA +GCCGGGCGCACTGTTGTGCACCTGTAATGCCAGCTATACAGGAGGCTGGGAAGGAAGGAT +TGCGTGAGTTTAGGAGCTCGAGACCAGCCTGGGAAACAAAGGGAGACCCCAACTCTACAA +AAAAATTGTTTTTAAAAAATCTGACAGACTACAAGAGCAATGAAGAGGAATCAGTCCCAT +CAGATATTCAAACACACCATAGAACCTCAATAATGTAGACAGTGTGGTGCTGGCACATAG +GTGGACCAACAGTGGACTGGAATGGAAACCAGAAGTGATCCTGCAGGTATAATGGAACTG +AGCTCCTGCTATAGCTGGTGAAGATAGCCTTCTAAATAAATGCTGCTGGGAGCTGGGCAC +GGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGCAGATCAACTGAGG +TCGAGAGTTTGAGACCAGCCTGACCAACATGAGAAACCCCATCTCTACTAAAAATACAAA +ATTAGCCAGGCGTGGTGGCGCATGCCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGA +AAATCGCTTGAACCTGGGAGGCGTAGGTTGCGGTGAGCTTGGATCACACCATTGCACTAC +AGCCTGGGGGACAAGAGCGAAACTCCATCTCAAAAAAAAAAAAAAAAAAATGCTGCTGGG +AAAAGGTAGAAATGGATTCAGACCCCACAGTGTGCCCCACTACGTGAACCTGCTTCATTT +AAATGGAGCATGTGTGAGCGTCTGTGTGTAATGAAACAAGATAGGAAAGCACTCAACCTC +ACCGAGAATTAGGGAAACGCAAACTAAATCCAAACTGCAGTATCATTTAGTCGCCTGGAT +GGAATCATTGTAATCCTGCCACAAAAGCCTTGGCAAATGAAACCCCTCCGTCTGCTACGG +CCAAGCAAGGCTCTCCTAGAGAGGCTCTCCGGGTATGTGCCCAGGAGACGGGGACAACAC +GTTCACAGCCACACCGTCCGTGGTGACGCACACGTCCAGCAGGCGAGGACTGAATGGCGT +TCCTCACGAGGAAGGGAAGGCCCAGCGATGCCTGTCAACACGGAGGAGTCTAAAAGCAGT +GACGGGGAACAGCAACAGCAGAGACTGCAAAGTACAAGCCCCTATAAATCAACTTTACAC +TGCACAGCAAGCAATGTGGTGTTTAGACACATCTGTACAGTGAGACTCAAGAACAGTGAG +GATGTGATTCACGCAAGACGTGGGGCAAAGGTGCCCTCAGGTGGGGAGGGCATTGCTACG +AGGAAGAGAAGGGCTCTGAAAGCGCGGCAGTGTTCCGCTGCAGGCCTAGGGGTGAGCCGC +TTTTGATGACTCACTGAACCTCGTCTAATGGGCGCAAGCTTGCCTTTTCACGTTAAAATG +CAAGAGGCAGGGACGTCTCCCATGCTCCACAGCACCCTCACGTGGGGTGGCGCCTTCGCA +AGTGGACTCAGCGGCCCCACTAACCCCCGAAATGGGGTCGCGCCTTCGGAAGGGGACCCA +GCGGCCCCGCTGAGCCCCGGACATGGGGTCGCGCCTTCGGAAGGGGACCCAGCGGCCCCG +CTGAGCCCCGGACATGGGGTCGCGCCTTCGGAAGGGGACCCAGCGGCCCCGCTGAGCCCC +GGACATGGGGTCGCGCCTTCGGAAGGGGACCCAGCGGCCCCGCTGAGCCCCGGACATGGG +GTCGCGCCTTCGGAAGGGGACCCAGCGGCCCCGCTGAGCCCCGGACATGGGGTCGCGCCT +TCGGAAGGGGACCCAGCGGCCCCGCTGAGCCCCGGACATGGGGTCGCGCCTTCGGAAGGG +GACCCAGCGGCCCCGCTGAGCCCCGGACATGGGGTCGCGCCTTCGGAAGGGGACCCAGCG +GCCCCGCTGAGCCCCGGACATGGGGTCGCGCCTTCGGAAGGGGACCCAGCGGCCCCGCTG +AGCCCCGGACATGGGGTCGCGCCTTCGGAAGGGGACCCAGCGGCCCCGCTGAGCCCCGGA +CATGGGGTCGCGCCTTCGGAAGGGGACCCAGCGGCCCCGCTGAGCCCCGGACATGGGGTC +GCGCCTTCGGAAGGGGACCCAGCGGCCCCGCTGAGCCCCGGACATGGGGTCGCGCCTTCG +GAAGGGGACCCAGCGGCCCCGCTGAGCCCCGGACATGGGGTCGCGCCTTCGGAAGGGGAC +CCAGCGGCCCCGCTGAGCCCCGGACATGGGGTCGCGCCTTCGGAAGGGGACCCAGCGGCC +CCGCTGAGCCCCGGACATGGGGTCGCGCCTTCGGAAGGGGATCCAGTGGCCCCGCTGAGC +CCCGGACATGGGGTCGCGCCTTCAGAAGGGGACCTAGTGGCCCCGCTAATCCTCGAACGG +GTCTGGTCCTTGCTCTTGTGAATGAGACTGATGGACGGTGCCCGCAGCTCACTTCCTGGC +CAGCACGTCTGGAATTCCGGTTTTGTTTCCTCACTTGCAACCATTAAAGTTCGCATGCAA +AGCTGGAGACACATTTTGACATCTTGGTCAAGATGCCCCATGCCTTGAGGTTACCGGTCC +TCATCCACCACCTGGTCTTAACGTTTCCTCTAAGGCCACCAGCAAAGTGGTCATGACCTT +AGTCTTAGGTTGAACAATGTCATCTAAATGTACTCTATGAAAAATCAGTTTGTTCTGTAG +CAAAGGTGTTTTCAATATTGGTGTGTGTGACATGGGATGCTCAACAAAACCAGGCTTTTA +TCCATCTTTTAAGGTTTCTAAACTCTATAGATGGTAGTTTTCCTTCTGGGCCATTTAATA +AGATAATACAACAAGGCTGACCCCATGACATGAGCCCTTCTCAAGGGCAGATTTGGGCCC +AAAGCATTACAGGCCTGAAGACTGTTAGACACGGCTGCGTGAAAAGCTCAAATTATCCTC +TCTGAAACACTCAGGCCGAAAGTGCCTTCCAATGTCAATACATAGTGCGGAGACATTGGT +GGGCCTTTGTTTCCTGTCTTATTCTCTGACAGCCCATAATAGCAGACATTAGATTTGGAG +TATTTTTTAAAATCGAAACTGAAAAATATGTAAAGCCATCCAGCCATCTGAAGCAGTTGA +TTCAGCAACCCTCATGGCTGGATAAAACTTTATCCCAGCCGATGCCAGCTTGAAAAAAGC +CGAATGAAACCCTACAGAGCATCTGCAGCCACACGCTGGGAGAAATCCTCCCAGGTGCCA +TCATCTACGTGGTGTGCGCGGCGCAGCGGGACGGGAGGGCTGCAGTGTGGTGTGAGCGGC +GCAGCGGGATGGGCGGGTTGCCCCGTGGTGTGCGTGGCGCAGCGGGACGGGCGGGTTGCC +CCGTGGTGTGCGCGGCGCAGCGGGACGGGCGGGTTGCCCCGTGGTGTGCGCCGTGCAGCG +GGACGGGCGGGTTGCCCCGTGGTGTGCGCGGCGCAGCGGGATGGGCGGGTTGCCCCGTGG +TGTGCGCGGCGCAGCGGGATGGGCGGGTTACCGAGGTGCAGCCAGCAGCCCAGACAGCTA +TGAGCACTCAGTGGACTTGGGCCCAAACACTGGGATCCAACTCCATCAGAAAAGCACATT +ATTAAAGGAATTCGTCCATTTTTCTGTATCTTAAAAAGACACTGCGGACACCAAAGACCT +GGTATCTAAACACTTGACATATGCCTAATTTTAACTTAAAATGCAGTCTCCTATCCCAGA +TCCCTCTGATTTATTCTCGGATGTCAACATTCCCCTCCGCGCTGAGCTCAGCACGGAGGC +TGTTGTGCGGTACCTACAGCAGGTGAATGGGCGGCTGCCGACCGCCCCGAGCCACGCCCC +CAGGCCAGGCTCCTGAAGGAAAGGTGCGAGCCGGCTCATATCACAGCGCATTTTCTATCG +TTGAATTAAAGGGAGTGCCGAAATCCTAAAAAATCTAAATTAAGATTTTTAAAATGTTTT +TTCTTCAAAACTGGACAAAAGATCAGACAATAATACTTAGTGGCTTATAATGCTCTGACC +TAAAATATACACACCACTATATACGCTCCCCGGCTCCCTCCAACCCCGCCAATCTACCAG +CCACTCGGGAGCCACCTCAGTCATCAGACCCAGGGCAGCAGACAGTGCCTGTGTTCACGA +CACCCTTATCTGACTCAGTAGCAGCCCAAAGCACGGGCGGTGGGGCTCGCAATCTGGATA +CGCCAAAGAGAAGCCACAAAGTGCTTCCTTTAAATGACGAGCTGAAAGTTCTTGACGCAA +CAAGGAAAGAAAAAATCCTATGCTGAGGTTGTTGCTCAGATCTTCAGTAAGACCAAATCT +TCTATCCATGCAATTATAAACAGTATATTGTTATCCTTGTTCTATACTATGATTGTTGCT +AATCTCTTACTGTATCTAATTTATAAATTAAATGTATCACAGGTATGCTGTATAGGAAAA +AACACAGGAAATACAGGGTTTGGTACAATCTGAATCCCCTGGTGGTCTTAGAATGCATCC +CCTGAGGATAAGGGGAGACTAGCATACTCCAAACACACCCCCTCTCGCACTCCCCAGCTG +TTTCGAGAGCAGAGGACAGGATCACATGGCCAGTAAGGTGTCTTGGGGCTGACACTTACA +TGGAATTCCGTGGTGTTGAGAATGTGGCGCCCGTCCGGGCTCCAGCACGAGGCCACCAGC +CCGGCTGAGCCCTCGTCTATTTTGCAGTGCCATTCGGGCTGCTCTAAAGACCAGACCTGG +ATTGAGAGAAGAAAGAAACACACAAGTGCAAACTCATCAGCACCGAGAGACAGCGAGGAC +AGCTCGCTTAAACGCAGCGGAGACCCGACCGCACAGGGTGTCTTCAAACTCATCAGCAGT +CTATAGCGAGGCCTCGCCGAGAGACAACTCCCTTAAAACCAGCAGAGACCCGATCACACA +GGGTGTCTTTTAGAACCTTTCATGATGAAGGGCTGGTGCTGGATTCCAGTGTAAAAGTAA +GCCACGCTTCTTGGTGATTTCATTTCGTTGTTGTTTTAAAACTGTTTATTCACATTGTCA +TTCCTAAGACCTCATTTAGTTAAGCTTTGGACACAGAAGAAAACACGACTTCTTAGGACT +TCCTGAAACACACCACATCCGCGTGGCTAGATTGCTGTCAACACCTCCGTTTCTCAACTA +TATTGCTTAGAAATTAAGACTACGTTGGAGTTTCCTTAGTTTAAATGTTCTTAAACTTTA +GAGAACGTTATAATTTCAAAAGAAAACTGGCTTTGAGCTGCACGGACTTTTTTTTCAAAC +TAGAAAGGCACAGAACAAAACCCCTCCTTCCCAGGGGCCCTCAGAAGGTGTCCAGATTCT +AAGCGACACGGCAGCACACACCTGCACCAGCCCTCGCTTGTACATGGCGCACAGGATGAA +GAGCGAGTCTGCCGACCACTCGATGTGCTGGATCTGGTCTAGGCACGTGTACAGCTGAAG +GATCTGAAGGGTGTTCACATCCCGGACCACTAACCGGTACTGGACACAGGAAGCCTAAAA +AATATGAGAAAGCAAGCACCTGACATTCTCCACTCCAAAAGAGGGGGGCCTTCGGAATGC +TACTGCCCTGGCCTTCAGTGACTGTGGCCTTCTCTCCTGCCAGAGGTTTCATGTCTAGAT +CACCAGTGACATCCCCAGCCCCTAAAGATCAGTTCAGTTCATACAAGGGTAATGTTGAAA +TATACAAGCCAGGTTTTAATATTGCTATACTCTATTGTAAAGTATAAAAGTATGTTTTAA +CTCGCTACTTAAAGCTTTAAGACATTTTTAAGTCCCTTCTTATCTGTATGTTAAAAACTA +AACTTAAATGGGAAGTAGCATTGGGAGAAAGCTCTTCTGTGAACTAATAACCAAAATCCT +CTGCTAGTTTTATAAACACTTTTGGACAATTTCCTCAAATTTATAAAGGGTAAGAATTGA +GGCTTCACAGATGACAACGAAAATGGCAAGGAATGCATCAATCTTCTTATGCAGTGCCGA +ACTCAGAGCCAAAACAACAGAAGATCAAAAGACAGGCTTTCACTTCTGCACACATAAAGA +TGCTTCGCAAATGCTCATTTATCTCCATTAACCTATTCCTAACACGAAACGGGAAATGTT +TAAGTGTTAGTACTATTTTCTTAAAGATAGTTTCTTCTTGTCCATATTTGTTCATTATGT +CCCTATCCAAGCAAACAATTTCAAGTAAAAATAACGCCTGAGTACTCACCTGCTGAATGT +ATATTTTACTACAGTTTCAAGATCAAGAACTGATGTTTAAATATTAACTGCTTCGTTAGT +TTTACTTATCAAGGTCAAAGTAGTTTGTGTTTTATGAACCGATATCAAAAAAGAAAGCCA +CGTTAGTTTTCCGTGGGAGAAAAGAGAGACAGGCGGGTGACGGCAGATTGGAACAAGGAG +CTACCACAGCACTTACTTTCTCACACTGTAGCTTTGAAAACTGTGATCAGTTACAGTGAA +TTCCTTATGAAATGGAATATTTTTACCAACACCTTGAGGAACCACATAAACTCTACTGCA +AGATATGAAAACTAGAAACATGGACCTGCTCTCCCCAGTCCTCAGGGCTTTCAAGAAGAT +GATTCCAGTAACAGATCATTACCAAGTGTTTCAGGGTATTTTGACCAGAGTGTACAAGCT +GGAAAAAAACACCCAAGTTAAGCAAGCAGATGTAATCTTTCTCCTTATAATTCACTGAAA +TTTTCATAAATGGTAAAAACAAAAAACAAACCTCTCATTTAATTGAGGAGGGGGGCACAT +TGAAAATATACCAAGGCTGAGATGCCATTTAAACTAATGAGGTTTTCTGTTTTGTAGCTG +ATGCTATTTTATGTGATTTGGAATAAAACCTCCCTGAAGAGGTAAAAAACGTAATTTGAG +AGTTAAACTCTCAAAAGCTAGACAGAGCACAGGAATGTCAGGAGTGGCAAAACCTGAAAA +AGCATCATGATACATCAGTCAGTTAGTACAGGTGGTGGATAAGGAAAACGAAGCCCACTT +TTTACGAGGCATGTTTCTTCTTAGTGGCTTTCCAATGCCAATTGTCCCCCTCTTCTGAGG +ACATACATACTAGGCATCCGGGTTATCCCTCTCTTCTGAGGATATACACTACTAGGCATC +CAGGTACATACACTATATGTTTTGAAGCTTAAAGTTATAGCTCTGTGATTTAAGCACCCT +TCTGCCACCCATGGAACGAAGACCTCAAATCCCAGCCATGAGGACAACTACTTCCTTACC +TGGGGATAGAATACTAGTATTTAAATCATTTATTCGGCATGTGGTAGAGGAGAAGAGAAT +TAGAGGAGAAGTAGAGATGACAAAGTAGCCACACCACTTACCAGTTTACAGGCAACAGAA +TCATCAATTTGCCTTTTGTGACAAAGTAACAACAAAGAGCCGACATCTCCTATACCCTCA +CCTGTGTGCAGTCGGCACTGCCGATACCCACCTTTCCAAGGGCACCTCCCCAGACCCCCC +ACCTGTCTACGGTATCTTCCTGGGTCCCGCACCTGCCCGGGCACCTGCCGGGGTCCTGCA +CCTGTCCGGCCCCCATATCTGCTTGGGGTACCTGCCTGGGCCCCGCACCTGCTTGGGGTA +CCTGCCTGGGCCCCGCACCTGCTTGGGGCACCTCCCCGGGCCCTCCACCTGTCTAGGGTA +TCTTCCTGGGTCCCGCACCTGTCTGGGGCACTTGCTCAGACACTGCACCTGCCCCGGGTA +CCTGCCCGGGCCCCGCACCTGTCCGGGCACCGCACCTGCAGGATCCCCAAGCTGCCTCCA +CCCACGCGGCCGCCCCCGGCCCTGCCCGCCGGGGACGCTGGCACCGAGGATGTCCTGCCC +GTGGCCCAGGTCCCCGCCGCTCACCAGGTACTTGCCGTCCGGGGAGAACTTGCAGAGTAA +GCTGGAGAGCTTGAATACCTCGGAGAAGTTCATGGCCGCCGCCTGCCGCGGGCGCCACCC +TGCGCCCGAAAACCCGCGGGACCCCTGGGCGCGCAGCAGGCTGCAACAGCCGACGCCGGC +CTCCGAGGCCGGAAGTCAGAAGGCGGAAGTGAACTGCAGCCTATCAGCGCCGCCGGCTTC +CGCGCGGCATTGTGGGGCTTGTAGTTCTTGTGCCGCAGGGCTTTAAAGGAAACGCCCACG +TTTCTTCCGACCAGGGATTTCCGACCCGAGAACCTTACCTCAAAGGCCGGGAGGCCTTTG +AGCACCTCCAGCTAGGGCTGCTGATAAAAATGTAGAAAGCACAGTAAAATTTGAATTTCA +GATTCACAACAAATCTAGTTATAAGTATGTTCCCAAATATTGCACGGGACATGCTAATAC +GGAAAAATTACTCGCTAGTCTGAAATTCAAATTTAATTGAGCGACCTGTGTGTCTGCGTG +TGTGTACACATGCATATATATATATTTATATTTATATGTAAATGTATGTTTACATGTAAA +TATATGTTTACCTACAAATATATCTTTAATAAGTAATACGGTGTCTGTCGCACATATATT +ATATCGTGTATGTAATGTATAAGTATTTATTTCGTTTGCTTGGGGTTTTGTTTGCTTTTG +CTGAGTCCGACCCCTCTACCTGCCGCCTGGCCCTTGCCTCACGCTCCAGTGCCACTGAGA +TCAAGGAGAGAACGAATTTGCCGCTGACTGGGCAGAGCGAGCGCGTGGATCGCGGCCACC +GCCCGTTCATCACCCGCGCGCATCTGGGCTGGCACCGGGCGAAGAATCGTGCGGGTCTGG +GACCTGGGGGCCCAGAGGGAGCGAGCTCCTGCGCGGGCGCTCGGTCCGCAGGTTTCGCAG +GCTCAGGGGCGTGCCTCGTTCTCACCCCCACTCCGGACCCCGGTCCTCTTCCCTAGACAG +CGGCCCCCTCCACCCCTGGCTCCCGCAGGCCGCTAGTAGTCCGCGCCAGGCCCCGCCGGC +GCCTCTAGGGCCCCCCAGATCGCGCAGACCCTGACATCCCCGCCTGGCCCTGGGTTCTGG +GAGCTGAGAGCCGGCCAGGGTCCTGCTCGTACCTCCGGGCGCCCAGCCTCGGGTCTGCTC +CCCGCGGACGCCCCAACCTCCCCGGCCGAATGGATGGTGGTGCGCGCGCGTCCTACTCCG +GCGGTGCCGGCCTTTTCTGTTGCCAAAACTAGACCCAAACCTCTGCATGGGATTCGTCTT +TGGGTCCCCACCCCGTGCGCCCAGCAAACAGTGGGTGAGCCATGAAGATGTGCGAGTCAG +CCGGACCCTCCCCGTCAGGCGCGGACCCGCTGCGGCCAGAGAACCCAGTCTGCGCCAGCC +CGGCTCGCTCGCGAAGCCACGGGCTTCACTGACGCGACTTTCCAAGACGTGGGGGTCACC +ATGGGCAGAGGACATCGGTTCGGAGCCAGATCACGGGCCCCATAAGCATCAGACCATAAG +CAGCGCCGCCACTGAGAGCCGCTCGGAACTCGCCCAGCATGTCGGGTCCCCTAGCCAGGG +CCTGGTGTACGTGGTCGAGGGCCCTGGAAGCCCCGATGGCCTAGGAGGAGCAGGCGGGCG +GGGCGGCGGGTGTCGCTGGCCGGTAGAGAGCTTCGGCCTGACCTAGCGCAGGTCTGGTGC +GCGCAGAGAACAACTCCAAGCGCACCGACGCCCGCGAGCTCCTTCCAAACACCGAACGGG +ATCCAGAGCCCGAGCCCACAGGCGGCGGCCGGGGGAGGGAGCAGGGTGCTGGCCGCCGCC +CGGGAGTGTTCGCGTCCTGGGTGACCCCTGGAAGGACGTGGGGCCCAAACTCCGGCTGGG +GTTGGGAGAGCAGCCCCCAGAGGCTCTCCGCGGGATCCTCTGCCGGGCGGGACCGTGGCT +CCACAGGAGAAGTGGGTGGCAAGCCCTGCTTGGCGGAAAGCAGCCGTTCCCCTCCTCCTG +GGCCTGGGGCGGCGCCCCTCACCCCTGTTCCCCGCCCCTCACCCCTGTTCCCCGCCGGCC +ACATCCCCTGCCCCTTGGATTCCAAGCGCCCCGCGCGCCGAGGAGCCCAGCGCTAGTGGC +GGCGGCCAGGAGAGACCCGGGTGTCAGGAAAGATGGGCCGTCTGGGGGACAGCAGGGAGT +CCGGGGGAAACGCAGGCGTCGGGCACAGAGTCGGCACCGGCGTCCCCAGCTCTGCCGAAG +ATCGCGGTCGGGTCTGGCCCGCGGGAGGGGCCCTGGCGCCGGACCTGCTTCGGCCCTGCG +TGGGCGGCCTCGCCGGGCTCTGCAGGAGCGACGCGCGCCAAAAGGCGGCGGGAAGGAGGC +GGGGCAGAGCGCGCCCGGGACCCCGACTTGGACGCGGCCAGCTGGAGAGGCGGAGCGCCG +GGAGGAGACCTTGGCCCCGCCGCGACTCGGTGGCCCGCGCTGCCTTCCCGCGCGCCGGGC +TAAAAAGGCGCTAACGCCCGCGGCCGCCTACTCCCCGCGGCGCCTCCCCTCCCCGCGCCC +ATATAACCCGCCTAGGGGCCGGGCAGCCCGCCCTGCCTCCCCGCCCGCGCACCCGCCCGG +AGGCTCGCGCGCCCGCGAAGGGGACGCAGCGAAACCGGGGCCCGCGCCAGGCCAGCCGGG +ACGGACGCCGATGCCCGGGGCTGCGACGGCTGCAGGTAGGAGGCCCAGGGCCGGGGGGCG +GTTCGGCTCCGCGGGCGGGGGCTGGAGCGCAGCGCTGGGCAGGCACCTGGGCTCGCAGCT +CCGAAGCTGGGAGGTGAGGGGAGAGCGATCGGGGA diff --git a/test/csq/ENST00000378322/ENST00000378322.fa.fai b/test/csq/ENST00000378322/ENST00000378322.fa.fai new file mode 100644 index 0000000..c50c501 --- /dev/null +++ b/test/csq/ENST00000378322/ENST00000378322.fa.fai @@ -0,0 +1 @@ +1 21995 21 60 61 diff --git a/test/csq/ENST00000378322/ENST00000378322.gff b/test/csq/ENST00000378322/ENST00000378322.gff new file mode 100644 index 0000000..e79e42a --- /dev/null +++ b/test/csq/ENST00000378322/ENST00000378322.gff @@ -0,0 +1,26 @@ +1 ensembl_havana gene 1 21995 . - . ID=gene:ENSG00000116213;Name=WRAP73;biotype=protein_coding;description=WD repeat containing%2C antisense to TP73 [Source:HGNC Symbol%3BAcc:12759];gene_id=ENSG00000116213;logic_name=ensembl_havana_gene;version=11 +1 ensembl_havana transcript 1 19292 . - . ID=transcript:ENST00000378322;Parent=gene:ENSG00000116213;Name=WRAP73-002;biotype=protein_coding;havana_transcript=OTTHUMT00000001471;havana_version=1;tag=basic;transcript_id=ENST00000378322;version=3 +1 havana three_prime_UTR 1 631 . - . Parent=transcript:ENST00000378322 +1 havana exon 1 891 . - . Parent=transcript:ENST00000378322;Name=ENSE00001755234;constitutive=0;ensembl_end_phase=-1;ensembl_phase=1;exon_id=ENSE00001755234;rank=11;version=2 +1 havana CDS 632 891 . - 2 ID=CDS:ENSP00000367573;Parent=transcript:ENST00000378322;protein_id=ENSP00000367573 +1 havana exon 1447 1572 . - . Parent=transcript:ENST00000378322;Name=ENSE00003534355;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00003534355;rank=10;version=1 +1 havana CDS 1447 1572 . - 2 ID=CDS:ENSP00000367573;Parent=transcript:ENST00000378322;protein_id=ENSP00000367573 +1 havana exon 2632 2737 . - . Parent=transcript:ENST00000378322;Name=ENSE00001659258;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00001659258;rank=9;version=1 +1 havana CDS 2632 2737 . - 0 ID=CDS:ENSP00000367573;Parent=transcript:ENST00000378322;protein_id=ENSP00000367573 +1 havana exon 4231 4308 . - . Parent=transcript:ENST00000378322;Name=ENSE00003685083;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003685083;rank=8;version=1 +1 havana CDS 4231 4308 . - 0 ID=CDS:ENSP00000367573;Parent=transcript:ENST00000378322;protein_id=ENSP00000367573 +1 havana exon 4394 4528 . - . Parent=transcript:ENST00000378322;Name=ENSE00003492457;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003492457;rank=7;version=1 +1 havana CDS 4394 4528 . - 0 ID=CDS:ENSP00000367573;Parent=transcript:ENST00000378322;protein_id=ENSP00000367573 +1 havana exon 5178 5264 . - . Parent=transcript:ENST00000378322;Name=ENSE00003480267;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003480267;rank=6;version=1 +1 havana CDS 5178 5264 . - 0 ID=CDS:ENSP00000367573;Parent=transcript:ENST00000378322;protein_id=ENSP00000367573 +1 havana exon 6229 6332 . - . Parent=transcript:ENST00000378322;Name=ENSE00000734306;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00000734306;rank=5;version=1 +1 havana CDS 6229 6332 . - 2 ID=CDS:ENSP00000367573;Parent=transcript:ENST00000378322;protein_id=ENSP00000367573 +1 havana exon 7984 8056 . - . Parent=transcript:ENST00000378322;Name=ENSE00000734303;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00000734303;rank=4;version=2 +1 havana CDS 7984 8056 . - 0 ID=CDS:ENSP00000367573;Parent=transcript:ENST00000378322;protein_id=ENSP00000367573 +1 havana exon 15900 16016 . - . Parent=transcript:ENST00000378322;Name=ENSE00000734299;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00000734299;rank=3;version=1 +1 havana CDS 15900 16016 . - 0 ID=CDS:ENSP00000367573;Parent=transcript:ENST00000378322;protein_id=ENSP00000367573 +1 havana exon 16642 16794 . - . Parent=transcript:ENST00000378322;Name=ENSE00003566716;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003566716;rank=2;version=1 +1 havana CDS 16642 16794 . - 0 ID=CDS:ENSP00000367573;Parent=transcript:ENST00000378322;protein_id=ENSP00000367573 +1 havana CDS 19165 19233 . - 0 ID=CDS:ENSP00000367573;Parent=transcript:ENST00000378322;protein_id=ENSP00000367573 +1 havana exon 19165 19292 . - . Parent=transcript:ENST00000378322;Name=ENSE00001870155;constitutive=0;ensembl_end_phase=0;ensembl_phase=-1;exon_id=ENSE00001870155;rank=1;version=1 +1 havana five_prime_UTR 19234 19292 . - . Parent=transcript:ENST00000378322 diff --git a/test/csq/ENST00000378322/ascii-art.txt b/test/csq/ENST00000378322/ascii-art.txt new file mode 100644 index 0000000..2f7835c --- /dev/null +++ b/test/csq/ENST00000378322/ascii-art.txt @@ -0,0 +1,9 @@ + +exon 19165 19292 +cds 19165 19233 +5'utr 19234 19292 + 19295 + xxxx + CGCGCAGCAGGCTG + A-------- + diff --git a/test/csq/ENST00000378322/ascii-art.txt-l b/test/csq/ENST00000378322/ascii-art.txt-l new file mode 100644 index 0000000..2f7835c --- /dev/null +++ b/test/csq/ENST00000378322/ascii-art.txt-l @@ -0,0 +1,9 @@ + +exon 19165 19292 +cds 19165 19233 +5'utr 19234 19292 + 19295 + xxxx + CGCGCAGCAGGCTG + A-------- + diff --git a/test/csq/ENST00000378322/end-overlap-tscript.txt b/test/csq/ENST00000378322/end-overlap-tscript.txt new file mode 100644 index 0000000..31e39dc --- /dev/null +++ b/test/csq/ENST00000378322/end-overlap-tscript.txt @@ -0,0 +1,9 @@ +1502 G C missense|WRAP73|ENST00000378322|protein_coding|-|331I>331M|1502G>C +1502 G C missense|WRAP73|ENST00000378322|protein_coding|-|331I>331M|1502G>C + +19291 G A 5_prime_utr|WRAP73|ENST00000378322|protein_coding +19291 G A 5_prime_utr|WRAP73|ENST00000378322|protein_coding + +19295 AGCAGGCTG A . +19295 AGCAGGCTG A . + diff --git a/test/csq/ENST00000378322/end-overlap-tscript.txt-l b/test/csq/ENST00000378322/end-overlap-tscript.txt-l new file mode 100644 index 0000000..31e39dc --- /dev/null +++ b/test/csq/ENST00000378322/end-overlap-tscript.txt-l @@ -0,0 +1,9 @@ +1502 G C missense|WRAP73|ENST00000378322|protein_coding|-|331I>331M|1502G>C +1502 G C missense|WRAP73|ENST00000378322|protein_coding|-|331I>331M|1502G>C + +19291 G A 5_prime_utr|WRAP73|ENST00000378322|protein_coding +19291 G A 5_prime_utr|WRAP73|ENST00000378322|protein_coding + +19295 AGCAGGCTG A . +19295 AGCAGGCTG A . + diff --git a/test/csq/ENST00000378322/end-overlap-tscript.vcf b/test/csq/ENST00000378322/end-overlap-tscript.vcf new file mode 100644 index 0000000..319cb9b --- /dev/null +++ b/test/csq/ENST00000378322/end-overlap-tscript.vcf @@ -0,0 +1,8 @@ +##fileformat=VCFv4.2 +##contig= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO +1 1502 . G C . . EXP=missense|WRAP73|ENST00000378322|protein_coding|-|331I>331M|1502G>C +1 19291 . G A . . EXP=5_prime_utr|WRAP73|ENST00000378322|protein_coding;type=no splice +1 19295 . AGCAGGCTG A . . EXP=.;type=ENST00000378322:3566625-AGCAGGCTG-A beyond; diff --git a/test/csq/ENST00000381157/ENST00000381157.fa b/test/csq/ENST00000381157/ENST00000381157.fa new file mode 100644 index 0000000..6b8552b --- /dev/null +++ b/test/csq/ENST00000381157/ENST00000381157.fa @@ -0,0 +1,903 @@ +>X X:2746809-2800879 +CCGGCGGTTCCCGGGTCTCTCTTCCCGGCAGCCGGGGCTGGGCACCAGGCGGCGCGCGGG +CTTGCGGGCAGGGGCTGCAGGGAGGAGGAGAGGACCCGCGCCCGCGGGGGCTGGCGGAGG +CGGGGCCGGGCTTCCGGACAGAGGCCAATCGCTGCCCTCGGGGCCTCCAGCGCCGGCTCT +GGGCCGAGGCAGCCAGAGCGCGGAAGAGGTGCGGGGGGCTGTAGGGGGCTGCAGGGGACC +GTGGGCAGTGGAGGAGGCCTGGGCGCGGCGGGGGGCCGGGGGGCGCAGAGGCTGCCCGAA +CGCCTAGGAGGTCTCGAGGGTGGGTGGCGTACAGCGGGGCGGGGGCGCAACCCAGAGGCC +GAGGCTGGGGGCTGGGGGAGGGGCGCCGGACTGGAGTGCAAAGGAGGGGCGAGGGGCGCA +GGGGGCTGGAGGTCAGAGGTTGCCCAAGCGCGAAGGAGGGGAGGGGTGCGGGGCGCGGGA +GTAGGCCAGGAGCGCTTAGGGGTGAGTGCGCCGAGCCAGGGCACCGAGTGCTGGGGAATA +CAGGCCGTCCAGGCGCGGCGGGGCGCGGGGAGACGGAGGCTGCCGGAGTACGGAGGACAG +ACGGGGCGCGGGCGTAGGGCTGGGAGGCTTGGGGAGGGGGGCGCGGGCCCAAGGCAGAGG +CTGCGGGAGCGCGGGGCAAGGGAGAGGTGCAGAGCGTGGAGGGGGCTCGGGGGCGCTTGG +GGAGGATGGGCGGCAGGCCGGGTCGGGGAGGAGGGGCGGCGAGAGGCGCAGGGGTAGGCC +GGGGGGCTGCACTGGAGTGACGAGGGAGGGGGCACCTGGCCGGGGGGCGCGGGCAGAGGC +AGCCCAAGCTCGGAGGAGGTGCAGATACTGGCGTCCGGGAGCGCAGGGGTGGTCCAGGGA +GTGGAGAGGGGTGACCGGGGGGCGCCAGCTGGGGTGGAGGAAGAGGATGCCCAGAACTCC +AAGCAGGTGCGCGGGGCGGCGGGGCAGCTGCTGACACCGCTGAGGTCGGGTGGTGTCCCG +GGGGCGTTGTCGTTGCTGGGCGCATGGGTGTTAAGACGCAGCGGGGTCGCAGGTGACTGT +GGGGAGGACAGGGGGTCAAGGGGCCCCTGGCCAGAGGGCACGAGGCTGACCTGGAGCGCC +AAGGAGGAAGTGCGGGGCGTGGAGGTCGCAGGGGCATCGGGGGAGGCAGGGGCCCCGTGG +GGCGCAGGTGACATGGAGTGGGTAGGAGGCCGGGGGTGACACTGGCGGGGCCTGCAGCCG +AGGGTGTCGAGACTGCCACGCTGTCGCCCCCAGGCCTGGAAATCCACGCGGATTCCCGGA +GACGGCGCCTCTGCTCTGCGGGTTCGTGGCGAGGAAGTCCACCCACTGCTCCCGGGCGCA +GGTCTGCAGGTCCGCGCCCACTGCCCGCGGCGCCACTGACCATGTCGGGTGAGTAGCTCA +AGCTGCTTCAGTTCAGCCTGCCTGTTCCTACTGGCTTGGGTGACAGATTGGTCTGCACTG +GGGAGAACCCCACTTTGACCGCAGGATTGCCCCAAACCCCGAGTCTCCCCCTTACTGCCT +CGCCCAGGTCTCTCTGGGGCTGGAGGGAATGGAGATACCAGCCTCAGCTGCTGGGAGGGG +GTGATTTACAGCAAGTGAAGGGGGCCTTGGGATTTCACCAGTTTCCTTTTGTAAAATATA +GTCCTGAAACTTTCAATGGGCTTGTTTCTTGGGAATAGCATTGAACTGCCTGAGACTGTC +ACTGCCTGGAAGGCCGATGGGAAGAAGTCTGTTCTCCTGAAATGGCCCTAAAGCTCTGGG +AAGAGGCTGCCTTGAGTTCTTAGAACTCAGACCACGGTTTTAATTTCTGTTTCCAGTACA +GATACAGGGATGGCCCGGCTTGGTGGCTCAGGCCTGTAATCCCAGCACTTTGGGAAGCTG +AGGCGGGAGGATTGCTTGAGGCCAGGAGTTTGAGACCATCCTGGGCAACATAGGGAGACC +ACATCTCTAGGAAAAAAATTTAAAAATCAGCTGGGCATTGCGGCACCTGCCTGTAGTCCC +AGCTACTAGGGAAGCTGAGGTGGGAGGGTCCTGAGCCCAGGAGTTCCAGGCTGCAGTGAG +CTATGAGTGCACCACTGCACTCCAGCTTGGGTGACAGAGTGAGACCCTGTCTCTAAAAAA +CAACAACAAAATAAGAATCCAGGTTAATCCTCCTGCAGGCAGAGGGCTGGCTGGCAAGAA +TGGCAGGAAAGGCCTGCCCCCGCCAAGGACCGGTGAGCCCCATCTCCCTGCCCTTGGGTT +TTGTGGACATCAGATAGACTGGTTGACTTAAGAGGCCTAGATATGTGAACAGAGTGTAAC +CTCTTCCCATAAGAAAGATGCTGGTTCTATTTTCTATCATTAAATCATTAAGACACCTCC +TTCTTGTACCAGACCACACTGGATCATTCTATGAGTGCATTTTATGTATTTATTTTTAAA +TGTATATTTTTTAAATTTTGTAGAGACAGGGTCTTGCTATGTTGCCCAGGCTGGTCTTGA +ACTTCTAGGCTCAAGCAGTCCTCCTCCTTTGGCCTCTCAAAGTGCTGGGATTACAGGCAC +GAGCCACCACGCCTGGCCATGAGTGCAATTTAAAACACACAAACAGAACAGATGACTTTT +TTATTCAGAGGAGAGATTTGGTAAATCACAGAGCTGCTTCTCTCCTGTTTGTTCCCACTC +TGGACTTAGAGATGAAAATTGTCGGGGCAGGGATCTTAAGGGCTGTTTTCATGAGGTGTA +CTGGAAGAGTCTGTTCCAAGGAATGGCAGAAAAGATTCTCTGTTCTAGGGACGCGTTTGG +AGCTCTCTAAAGTGAAAGCCACACATTTCCCCAAGCCTGCTAGGGTCTGTATAATAGCAG +CATTCAAGACGGACATTCGCATACATCTTGGTCAGCCTCGTGCCAGAAGAGAAGACTCAA +CTCTTTGCAGAAAACAAAAACCACCTTTGAGTAGAAAAGGGCTGAGAAGGAAGCTGCTAA +GGTTATTTTGGGGGGTGATCAGAAGATTCCTTGAGTGCAGGGGGGCAGGCAAGGGGTAGA +AAGAAACTGTTGTCACAGATTCATAAAATTCTCAGCCACTGTAATCTCCAGACTGGACTT +GATTTTGTGACAATGTCTCCTTTTTGTGGGCTGTGGTGCAGTGACAGGTTTTCTTGCTGT +TTTTCCACTCCATGCCGTTGCTGAAAGTGTCCGCCGCAGTGGCACTTGGAGTGGAAACTC +CCTCTTTGAATGCAGTAGCATTGGATAATTGTGGATGTTCTCTGGCGTCTGGCGCCGCAC +CAGGACTTGATCACCAGTTGTTTCTTCAAGGCAAGGCGATGTGGAAGCTAAGCCCTGTCA +ATCAATGTTTCATCTTCTGTTCTATTTCAATCTGCTGGTCTGTCTTTGCACTTTAGATGG +GTTTTACAGTGTCCTGGATGGGAAGCGGCTAACCTTCAGGAGGTGCACATTTTTGTTCCA +AAGCAAAAGTCTGAGTCTCGGATCCCTTGTTGCTGGAGAGAGCTCGTGTGCCAACTGGTG +TTGTCTTGTCATTGTGTGACTGTGGTCAATATTCCCTCCACTCTAAACCAAAGAGAGAAA +CAGGGTATCCAGTAGTTCCATAAAACTCTCACTCTAAATGCAGCCCTGTCTGCATTCTCT +TTTGTGTTTGAGATCAAGGTGGGTGTGGGCAGGGCTGGTTCCTCCTGAGGCCTCTCTCCT +GGGCTTGGTCCTCACAGGGTCTTCCCTTTGTGTGTGTCTGTGTCCTAATCGCCTCTTTTT +TTTTGAGATGGAATTTTGCTCTTGTCGCCCAGGCTGGAGTGCGATGGTGCAATATCGGCT +CACTGCAGCTTCCGCCTCTTGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCTGAGTAGCT +GGGATTACAGGTGCCCGCCCCCATGCCCGGCTCACTTTTGTATTTTTAGTACAGATGGGG +TTTCTCCATGTTGGTCAGGCTGGTTTTGAACTCCTGACCTCAGGTGATCCACCTGCCTTG +GCCTCCCAAAGTGTTGGGATTACAGGCGTGAGCCACCACGCTTGGCCTAATCTCCTTTCT +TATAAGGACACCAATCCTATTGGATCAGAGCCCACCCTAGTGACTTAATTTTATCTTAAT +CTCTTCTTTAAAGACCCCATCTCCAAATACAGTCACATTCTGAGGTCCTGCAGGTTATGA +TATTCATATATGAATTTTGGAGGTGCACAAGTCAGCCCATAATAGGATAACTCATTTATT +TGAATACTACTGTGTTTTTCTGCTGGGGCTGCCATAACAAAGTCCCACAGACTGGGCGGC +TTAAACAACACACATTTACTCTCCCACAGTCTTGGAGGCTGGAAATCTGAGATCAGGGTG +TGGGCAGGGCTGTTTCCTCCTGACGCCTCTCTCCTTGGCTTGTAGATGTTGTCTTTCTCT +GTATCTCCACAAGGTCATCCTTCTGTGTGTGTGTGTGTCTGTGTCCTCATCTCCTCTTGT +AGTGAGGCCAGCAGTGCTACTGTATTAGGGCCCACCCTAGTGACCTCATTTTACCATAAT +CACCTCTTTAAAGACCCCATCTTCAAATGCAGACACATTCAGAGGTTCTGTGGGGTAGGG +TTTCATCCTAGGCGTTTCAGGATGGGTTATCATCCGTCTATAACACCCATTAATCCTCAT +GTTTTCCCTGAGGTCCCCATGAAGAGCTATAAAGCCAGCGCATGTGGTTATCAATCAATG +ATCACTCTGCCATTTCTCTTAGTTGTCACTGAGATCCTCATGAAGAGATTAAAAAAACCA +GCGCACATCGTTATCAATCATTGATCACTTTGCCAGTTCGCATAGTTGTCACTCACGTCC +TGATGAAGAGATAAAAAGCCCATGCGCATGGTTATCAATCATTGATCACTCTGTCATTTC +TTTCAGTTGTCACTGAGATCCTCATGAAGGGGTAAAAAACCAGAGCCTGTGGTTATCAGT +CACTGATTGCTTTGCCATTTCTCTTAGTTGTCACTGATGCCCTCATGAAGAACTATAAAA +CCAGCACAGGTGGCGATCAATCACTGATCACTTTGCCATTCCTGTGTGTTGTCCTCTGCA +CCTTGCTTTGGGCCAATTCACTTGCATCATCCTTTTCTCTAGACAGCCAGAGGGCCCTCC +CTGGCAATGGAGATGAGACCTTCTTACAGGTTTTGGAACCCTCAAATAGCTCCTCATAAG +CCTCAGGATAATAGAAAAGGCTGCATATCACCTTTGTAATCCGGGCCCTCTGACCCCATC +TCTTCCTGTGGGTCCTTGTTCTCCAGCTGCTGTTGCTACGCTGTGAGGAATGCAGGATGC +AGCATGCAACCTATCATCTCCACCTCTGGCCTTGGCTGGTGGATTTTTTCTGCCTCTTCC +TTCTTTGCCTTATTATTTTTGGTTCAGTTTCTTATTGGAGGCAGGAGACAGTAGCTATTT +TGAGGGCTTTTGTTGGTGTTGGAGTCAGAGGTGACCTCGGACATTTAATTACTCGTTGAA +GCCCCGGTTTACTTGTTTTTGAAGCACATGTCTGTGTTGGAAAGGGAATTAATGAGAGCG +CAGAGGTATGCCCTATCTACACACTCCTGGAGGGATGGGAGCCATATTCATTCTTGTTTG +TTGCTCCACTGATTTCTTGATGGATAAGTTCTTCCTGGCCATTTATCCCTGAGCTTGGAT +GGTGCCCTTTCAAAAACTGCTGCCAGCCATAGGACTTGCCTTGCAGTATCGAAACACCCA +TTTCTTAGGGCTAATGTTTCTCATGGAGCTGTGGGTGTCTGAGGACAGAGCTTGTACCTT +GTCAGCTGCTGGGCCCAGCACCTAGCAGATTCTCGTGCCTGGGAATTGCCTGGGACGTGA +ACCCACAGTGAACGTGTAATGCACTGAGAGCACGTCATTAGGCCCACACAGACATCTTCT +GCCCCTTCACCTTCTTTGTCTTCTGCCTCCAGCTTCAATCCTTCACTCTTTCTCTAAGCA +GATGCCCTTATGTGTGCAGCTTATGGCATAGCACTGTGGACTGGGATAAGCAGTGTCCCC +CATAAAACTCATGTCCCCCCAGAAGCTGTGAATGGGACCTGTGAACCCAAAAGTATCTGA +GACAGGTCTCAATCCATTTAGAAAGTTTATTTTGCCAAGGTTAAGGACATGCCCGTGACA +CAGCTTCAGGAGGTCCCGACAACATGGGCCAAAGGTGGTCGGGGTACAGCTTGCTTTTAC +ACATTTCAGAGACATGAGACATCAGTCAATACATGTAAGATACACATTGCTTTGATCTGA +AAGGGTGGGACTACTTGAAGCAAGGGGGTTGCGGGGGGTGGTGCCAGGTCATAGGTAGAT +TTTTAAATGTTCTGATTAGTCGAAAGAGTTATTATCAATAGAAGAGAATGTCTGGGTTAT +GATAAGAGGTTGTAGAGACCAAGGTTTTATCACGCAGATGAAACTTCCAGGTAGCAGGCT +TCAGAGAGAATAGATTGTAAAGGTTTCTCATCAGACTTGAGGTCTGTGTGGATGTTTATG +GTGGTCAGCTTTTCCTGAATTCCAAAATGGAGGAGGTTATGATGAGGCATGTCTGACCCT +CTCCTCATTATGGCCTGAACTCGTTTTTCAGGTTAACTTTGGAATGCCCTTGGCCAATTA +GGTAGTTGCGAGGCCTAGAATTTTAGTTTAGGTTTACAGACCTTATTGGGAAATAGGGTC +TTTGCAGATGTAATTAGTTAAGCATCTCAAGATAAGATTATCCTGGAATATTTGGGTGGG +CCCTAAATCCAATGGCAGGTGTCCTTCTAAGAGATAGAAGAAGAGACACAGACACAGAGG +AGGCCATGTGGAGTTGGAGGCAGAGATTGGAGTAATGTGGCCACAAGCCCAGGGACATCT +GGAGCCACCAGGAGCTGGAAGAGGCAGGAAGGACCCTTCTCTAGAGTTTGGTTTTGGAAT +CCTGGCCTTCAGAACTGCAAGAGAGTAAATGTGTGTTGTTTAAGTCTCCCAGCGTGTGGT +ACTTTCTCACAGCAGCCCCAGGAAGCTCATTCATGGGTTTGCTAGGGAAAGGAGTCAGCG +ATGAGCCCACCAGTAAGCAAAATGAGCACAGCAGGTAAGATGGCACAAGAGATGAAGGGT +CCTGTGTCATAGGAGGTGAGGGACTGTGATGAGAAGGGTCGTCTTGGGGAGCAGGGTTTG +CAGGAAGATCTCTGAGGGATGGGTGGTTTTTTCCATGGCCACCATGTGCTGGGAGGAGAG +CAAGTTCCAGGTGAGTTAAGGGAGTGGTAGTAGCCCCATGGTAGTAGCACACATCATAGG +ATGTGCTTGAAGACCCAGAGGGGTTGAGCTGGACGTGGGGACTGAGTGTGGGGGATGAGA +TGACCAGCAGTCTGGACCCAGCTTACATTTGCAGACAATGAGAAAACCATTGGCGTTGGG +TTGGCTTTCAGGGCAGCTGATGGCTTTCACTGTGTGTTGGGGGAGAAAATGTGGTTTTTA +AGGACCGAGGAGACAGATAACAGGGACCAGAATCTACAGGGTGGAGCAGAGAATGCAAAG +GAGGGAAGCTGTGGCTCAGGGTGGTTGATGCAGAGACCCATTTTAAATGTTTTCTAGTCT +GGTGCGGTGGCTGGCTCACACCTGTAATCCTAGCACTTTGGGAGGCCAGGACGGGAGGAT +TGCTTGAGGCCAGGAGTTTGAGACCAGCCTGGGTGACAGAGCAAGAGACCCCATCTCTAC +AGAAAAGTTAAAAATAAATTAGCCAGGTGTGGTGAGCATCTGTAGTCCCAGCTACTCAGG +AGGCCAAGGCAGGAGGATAGCTTGAGCCCAGGAGTTCCGGGCTTCAGTGAGCTGTGATGC +TGCTGCTGCACTCCAGCCCTGGTGGCAGACAGAGCAAGACCCTGTCAAAAAAAAAAAAAA +AAAAAAGCCAGGCACAGAAGGACACCTGTAGTCCCAGCACTTTGGGAGGCTGAGGCGGGT +AGATTGCCTGAGCCCAGGAGTTCGAGACCAGCTTGGGCAACATAACCTGTCTCTACCAAA +AATATAAAAAATAGCTGGATGTAGTGGTGTGCACTTGCGGTCCCTGCTACTCAGGAGGCT +GAGGTGGGAGGATTGCTTGCTCTCAGGAAGTCGAGGCTGCAGTGAGCTGAAATCATATCA +CTGCGCTCCAGCCTGAGCAACAGACGGAGACCTTCTCTCAAAAACCACCACCACCACAAC +GTAATGAACAACCCCAACATTTTCTGTTGTGCCTCTCGGTTAAGATCTCAGGTTAGTTAT +GCAAGAGTAGAATGTGGGATTGGAGGCAAGTGGACTTCTCCTTACCCCAGAATTCATGTC +ATAAATGCTCTGCACAGACGAGGCTTCTGGGACTCTTGGGGAGACCTAGGAGGTGGGTAA +TAGGGATCTGAATCTACACGGTGGAGCTCATGACCCAGGTCAGATGATGCCAAGTTTCAT +TTTATACATTCTCTGTTCTTCTTCTCTGCTCCTTAAGAGCGCAGGTCAGTAAGTGGGGTT +GGAAACAGTGGACTCTTCCTTACTGGGGTATAGGAGTTGGCACGCTAAATATTCTGCAAA +GCTTGCTCTTGCAGGACCAAGCATCTAAATAGTAAGGTCTAACCTCAGTCATCTGTTTCT +GGAGGAAAATCCCAAAGCATGGCCTTTGGAGTGTGATTTAGCCCTCATTCTCAGATTCAG +TGGTGAAGTTCAGAGGGGAGCCAATCCCTCTGAGCATCTCGAAGGTGGACAGAACAGTCA +GCTCAGGAGGAAATCTCAAAACAACGCCCCTCCTCGGGAGTTCTCTTACCTTTGTCATTG +TAGTTCCTAAAGGATGCACTCCTTTTCCTTTCTATTCTTTAATTCACAGGGTCCTTAAAC +ATGGTTCCTCAGATTTCAATAATCTATACATTGGAGATCACAAAGAAATCTTAATACTGC +CAATGAAAGGCTAAAAATTGTAAATGGCACTTTATTTTCAGTTTGACATTACTTTGCTGA +TGATTCTTTTCATAATATATATGATTTGATTTACCTTATTTTTTACTTTGCCATCTGCTT +TGCAATTAAATACACACACACACACACACACACACACACACATACACACACACACACGTT +TTCTTTTTAAAGACAGGGCTCTGCTCTGTAACCCAAGCTGGAGTGCAGTGGCACAATTAT +ATCTCACTGCAGCCTCCAACTTCTGGGTCAAACAATCCTGCCGTCTCAGCTTCCCAAGTA +GCTGGGACTACAGGCATGTGCCAAAAAAAAAAAAATTAAATTAAATGAATGCAAGTCCAT +TCTCAGTATGAAACACATACTGAAATAACTGCCTGAGAAATGGTACGTGGTAGATAAATG +TGCAGCAGATGTGCTAATTGGCCTGGGTATAGAAATTTAGCTATTTGGTCTGGGTATACA +ATTTTAGGTTGAGGACCATTGCACTCAGAGTTTAGATATGGTGGTTTGTTTTAGTGTCCA +CTATTCATGATAAGAAGTCTCAGTCTCATCCTTAATAGGATTGACCTGTATTTTTATTTT +ACTTTCATTTTCTTGGCATTTTCACAATGTTCTCCTTAGCCTTGGTGTTTTTAAATTCCA +GGAATATATTGTCAGGAAAAGGACTGCTGATTTTCTTTCTTTCTTTCTCTCTCTCCCCTC +CTCTCCTCTCCCCTCCCCTCCCCTCCCCTCCCTTCCTCTCTCTCTTTCTTTCTTTTTTCT +TTTTCTTTCTCTTTTGTTGCATACTCTCTGGGCTTTTTAAATCTAAAGACTGACTTTCTG +CTGTTGAGAACATTTCCTGTTTAATTTCTTTGAAAACTTTTCTTCTCTCTATTTTTTTTT +TCTATTCTCTTATTCTGAAACTCATGTTGGTGAACCTTCTGAATCACTCCTGTAGGCTTC +TAGCTTTCTGAAATTTTCCATTTGTCCCTTTATTCTACTTTCTGAGAGATTTCCTCAATG +ATGTTTTCCAAACCTTCTGTTATTTCGTTTTCATTTCAGCAAATCATATTTTTAACTTCT +AATAACTATTTCTTATCCTTGGAGTGATCTTTTCTATAGCATTTGATTCTTGGTTTATAG +ATGTATCCCTCTCCCCCTGATCTTTTGAAAGAATACTAATTGGTGCAGTCAGAATTTTTA +TGTCTGCCTGTCTGTTCCTTGAACTTCTATTCCATGAAATGTCTGGTATTTCTGGGGTTC +TTCCCATTCCACCCCATAACTTTTCAGTTTTCTCTTTTGTGGTGAAGGTGTTTTTCAAAT +ATCTGGTAATGGTTTATATCTATATGTATAAAAATGAGGAATGTCGGTTGAGCTGTACCC +ACTTGCCGACTCGTCTGAATTTGTCAAGCTTATGCTATAGGTTGGGAATTCCACTTCTGT +GTGATGGTAATTATTTTTTTCTTGGGCTTTTTGTTTCCTTTAGAATAGATCCTATCATCT +GATTTTGCCCCTGGTGATGGGTATATTTGGCCTCTGAGAATTCTGCAGAATTTCAGTGAC +TTCTCCAGTTTCTCTTATTGGCTGATGGTTTTCTCCTGCCTCTTTGTTGGCTTGGGGTTC +ACACTTGCCTTCCTTAGCACACTTTTTAGTCTGTTCTCCTTTTATCTCAGAAAGAAGGAA +AGAGAAACTAGGAGCTCCACATCCACCATCTTTGCTTGGAAGATTCCTGGTTTACACTTT +TAATTACGTGATTGAATTGATGAAAATGGATGGACCTTGAAAACATCATGCTGATGGAAA +GAAGTCAGACACAAAAGGCCATATGATGCTTAATTCCATTTACATGAAATATGCAGAACA +GGCAAATCCACAGAGATAAAAAGTGATTGGTGGTTGTCACAAGCTAGGGAAGGGAGAAAG +GGGAGATACTCCTTAATGAGTGCAGGGTCTCTTTTTGGGGTGATGAAATGTCCCAGGATT +AGATAGAGGTGGTGGATGTGCAACATTGTGATGAATTGTGTTCTTTACAATGGCGAATTT +TATGTCATGTGAAATTTACTGTGATAAATAAAAAGGAAATATGAAATTATTCCATTTTCA +AAAGGCTACATAGTGTTTGATTCCATTTATAGGAAATATCCAAAATAGGAATGTAGAGAC +AGAAAGCGGACTCATGGTTGCCAGAATGGGGAGTGACTGCGTAATGGGTACAGGGCCTCC +TTTTGGAGTGGTGAGAATGTCCTCGGATTGCCTGGAGTTAGTGGTTGCACAACATTGCGC +ATGGACTAAATGCGAGTCACTTGTGCACTTTAAAATGGTTTGTTTTATGTTATGTTAATT +TCCCGTTAATTTTTTGAGAGTTTGCATGGAAAGGTGAAGCTCTAAGCAGGTCGTATGTTT +AGGTGTGGGGATACCCATTATGCTGCTTAGAAATATGTTCACACTTAGGGCTCAGCACTG +GGGGTTCTACTTGGTAATTCTTTCTGCTTCCACACTCTTTCAAGATATGGGTCAGAGAAA +CCCTGGTGAGGACGGGGTAGGGGATTGGATCTCTGGCTCTGTTTTGGGCATTGTGTGATT +TTCGAGGTCTGTGGGTGAAGCTCACACAGTACCTTTACCTTGGCCAGCTCTGGGCTTTGC +AGATGCCAGTCCCGAATGCCTGCTTCCTCTCCCAACTCTGTCCTCTGCTTAGAGACAAAA +GAAGCCTTACAGACAGCTGAATGGGTCCATGACAGCTACGCCTGTTCTTGGGAAGTAATT +TTGATCAGAGCTCAGGCCTTTGGAAATGTCTAAAGAAGTAGTAATCACCATTATTATCAT +TTTAAAGCTAGTAACTAAGAAAACTATAGATAGATTATAGATAATGGTAGAGATAATTTA +TAATCTATAGACTGTAGGTAGATAGGTAGATGATTGAAAGATTGATAGATATAAATAAGT +AGATACATAGAGGACATATATATGATAGGTAGATGGTAGGTATAGATAGATGGATGGCTA +ATAGAAAGATGATAGGTAGAGAGATGATGGAGATAGATGGATGATAGATGATAGATATAT +AGATGATAGATAAATAGATATAGATGATATATGATAAATAGATGATAGAGATACATGGAT +TAGATAGCTAGATAGATAATAGAGATACATGATAGTAAGATAGATAATAAATAATAGATG +TGAAGAGGATTGGTAGATGATAGGTGGATAGATGGATGGATAGATGATAGGTAGATGGAT +AGATAGATGATGGATGGATGGATAGATAGATATATGATAGATAGATGAATAGATGATATA +GATAGATAGATAGAAGGATGGATAGATAGATGATAAAGATAGATCGATTATAGTAAGATA +GATAATAGATGTACAGAGAATTGGTAGATGATGGATGGATGGATGAATAGATGGATAGAT +AGATGATAGATGGATGGATGTATAGATGATAGATAGGGATAGATAGACAATGGATGGATG +GATATATGACAGATAGATGGATAGATGGATGGATGGATAGATAGAGATAGATGATAGTAA +GATAGATAATAAATAATAGATGTGCAGAGAATTGGTAGATCATAGGTAGATGGATGGATG +AATGGATGGATAGATAGATGATAGATAGGTAGATGGATAATATAGATATTATCCAATGAT +AGATAGATGATGGATGGATGGATAGATAGATGATAGATAAATAGATGAATGGATGGATGG +ACGGATGGATGGATGGATGGATGATGGGTAGATGGATAGATATGGACTGATGAAAGGTAT +CTTTTGTTCTACAGAATTAAGTTGTAAAGTTTGCTGTCTGTAATTCTCACTCCCAATGGA +GATGTCAGGAATTCTCGTTCTTTCTTCGTTCAAGGGTGGGGAGGAGGAGTCTACAGGAGC +AGCTGTAACAGGCACATTTTGGAATTTACCCCATTGGAATGTAAAGGTCAAGGAGGCAGC +CCTGTACCACACGTCTGGGACGCTTGTGTTTGTTATATTTAGTGCGAATTGTGGGTTGGC +TTTGCTTGGAGTGCTGCTTCCGGGAAAGGCGCTGTGGTCGCCTACATGCTGAGCATTTTA +ATTTCCATAGACAGTACACTGGGCTGCACACTGCATGGGACTTCTCGGCATTGCTGGCTG +CCCTCCTGACTGTTGTCTTTCTCCTGGCAACAGGGGCTTGGGTGCCCAAGAATCAAGTGG +TTTAAAAGTCATTACCAAAGTTCACATCAGTCTTGTGCACAGAGAATTAAAACTGCTGTA +AATTATATCTGCTGTGAGAGCTCCTTCCTCTCATACTGAGGCATTAGGAAATTGAATCCA +TTCTACCTAATGAAACAATGTACTTTTCCTTATGTTGTCTCTACCGCCTCATACATCCCT +GAGTTGAACTTGAAGTCTTTGTAAGAAATGGTCTGTCCAGAATTTAAATAACATGTTTGG +CTGCTTCTTTATGGAGCACGATTCTTTTCTTTCCTTTCTTTCTTTTTTCTTTTTTCTTTT +TTTCAGAGACAGGGACTCACTCTGTTGCCCAGGCTGGAGTTCAGTAGTGTGATCATGGCT +CTTTGCAGCCTTGACCTCCTGTGCTCAAGCGATCCGCCTGCCTCAGCCTCTCAAGTAGCT +AGGACTACGGGCATGCACCACCTCGCCTGGCTAATTTTTTTTTTTTTCCAGTACAGATGA +GGTCTTGCTGTGTTTCCCAGGCTGGTTTCAAACTCCTGGGCTCAAATGATCCCCCTTCTT +CGACCCTAGCACTGGGATTACAGGCATGAGCCACTGCACCTAGCCCAAAGCACAGTTCTT +TTGAGTGAGTTGGGTTACATCTTTGCTGTAACTCAGGTCATCAAGCCATCACTTCCACTT +TTTGCCTTTTGTTTTCACCTAAGATCTAAACACTTTGGGTGAGTTTTCAAGAGTCAAACA +CAACATAAAATAAGGGATAGTAGCTATGAGTTTCCATGGCATTGCAGCATCAGGAAATGG +GCATAGCAGTTGGGTTGACTTTGTCCCTTGTTTAAGGTTCCTTCATACTCCTCCTGTGTT +TTGTTTTGTTTAGAATGAAAGGAAGCATGTATGCGAATTAGAATACTGAATATTCACTGC +AAGTCGTGATTTTTTTTTTTTTTTTGAGACAGGGTCTCACTCTGTCATCCAGGCTGGAGT +ACAGTGGTGCAATCACGGCTCACTGCAGCCTCAAACTCCCAGGCTCAAGTATCCTCCCAC +CTCAGCCTCTCCGAGTAGCTGTAACTGCAGGCCTGCCACCACGCCCAGCTAATTTTTGTA +TTTTTCGTAGAGACAGAGTTTCACCATGGTGCCCAGGCTGGTCTCGAACTCCTGAGGTCA +AGCAATTCACCCACCTCAGCCTCCCAAAGTGCTGGAATGACAGGTGTGAACCATCACGTC +TGGCCCAAGCCATGAATCTTGGGAGAGGAGAGGAGGTGACTATGGCCCCGTCACCCCTGC +TGTCCCTCAGGAGTGTAACTCTGGTGTTTCTGTTGATTTTCACAGTGACTGATCAGGCTT +TTGTCACACTAGCCACCAATGACATCTACTGCCAGGGCGCCCTGGTCCTGGGGCAGTCAC +TGAGGAGACACAGGCTGACGAGGAAGCTGGTGGTGTTGATCACTCCTCAGGTGTCCAGCC +TGCTCAGGTAAGGCTCAGAGATGCGGCTTGTGCCCAGCTGGGTCCTATAGAAGGAGGGTC +ACCTCTCCCCTAAGAGGTCCTAGGAGTTATTCTGACGACTGACTGCCCTTCTTCATAGGC +CTGGATGGCCGGCAGTCATGATGGGCATCTGACGTTTGTAAGGAACCTTCGAATCATGTG +AAAATATAGGCGTGTGATCGGCTTCACAATACTTTAAAAAACAATACTGGGTTTGGTTAC +AGTTCATTCTCCCAACCATGGAAACTGAAAATTCAATTCTTTTTTGTTTGTTTGTTTTTT +GAGACAGGGTCTCGCTCTGTCGCCCAGGCTGGAGTACAGTGGTACCATCTTGGCTCACCG +CAACCTCTCCCTCCCAGGCTCAAGCGATCTTCCCTCCTCAGCCTTCTAAGTAGCTGGGAC +CACAAGTATGTGCCCCCATGCTCGGCTATTTTTATTTTTATGTTTTGTATTTTTGGTAGA +GACAGGGTTTCGCCACGTTGCCTAGGCTGATCTTGAACTCCTGGACTCACTCAGTCCACC +CAGGTTGGCCTCCCAAAGTGCTGGGATTACAGGCATGAACCATGGCACCCAGCCAAGGAG +TCTTTTCTTATAATTTCCTTTTATAATTCTCTTTGTCTTTAATTCTCAAATAAAGCAAAT +ACATAAATAAATGCGTCTAATGAATAAAGCATAAGGCTTCTCTTAAATGTCATACATTAT +GTAAGCAATAATCTTTTTCTTTCATCAACCATGGACCACTTAAAAAAATTGATTTTATAC +GAATGGGACGAGGAGGCATTTAATATGGTAGATGTAGCAGGAATTGAATGTCATATTCTT +TGACAATGAAATAATAAATCCAGACATTAATAGCTAAACTAAAAAGAGAACAAATAAAAA +ACCAACCAGTGTGTCCTCAGACGTTTGAAACTGGAAGTTTTAAATGAAATAACTCAATCC +GGGTACAAATGAAAGCTTGAATTATGTACTATTTCAGAAAATCACTGCAATGTGAGTGCT +ACCTATACAAAGCAAAGACAGCAACTACAGTGGTACAAGACAGAAAATTTAAATCAGTGA +AGAAATTATCCAGTTCAAATATATATGTATATACACACACGTATGCATATATATGTGTAT +ATGCACGCGTGTGCGTATATATGTGTATACGCACACGCATGCGTATATATGTGTATACGC +ACACGCATGCGTATATGTGTATACGCACACGCATGCGTATATGTGTATACGCACACGCAT +GCGTATATGTGTATACGCACACGCATGCGTATATGTGTATACGCACACGCATGCGTATAT +GTGTATACGCACACGCATGCGTATATGTGTATACGCACACGCATGCGTATATGTGTATAC +GCACACGCATGCGTATATGTGTATACGCACACGTATGTGTATATGTACACGTATGCATAT +ATATATACATGTATGTGTATATATTTATATATACGTATGTGTATATGTACATGTATGTGT +ATATATTTATATGTACAGGTATGCGTATATACACATGTATGTGTTTATATTTATATACAT +GTATGTATACCTGTATGTATATATGTTCAACTATATATTTTTATATACATGTATGTATAT +ATTTATATATACATGTATTATATATGTTCAAATATATTTATATACACATGTGTATGTATA +TTTATATACACATGTGTATGTATATATACACGTGTGTATGTATATTTATATACACGTGTG +TATGTATATTTATATACACGTGTGTATGTATATTTATATACACGTGTGTATGTATATTTA +TATACACGTGTGTATGTATATTTATATACACGTGTGTATGTATATTTATATACACGTGTG +TATGTATATTTATATACACGTGTGTATGTATATTTATATACACGTGTGTATGTATATTTA +TATACACGTGTGTATGTATATTTATATACACGTGTGTATGTATATTTATATACACGTGTG +TATGTATATTTATATACACGTGTGTATGTATATTTATATACACGTGTGTATGTATATTTA +TATACACGTGTGTATGTATATTTATATACACGTGTGTATGTATATTTATATACACGTGTG +TATGTATATTTATATACACGTGTGTATGTATATTTATATACACGTGTGTATGTATATTTA +TATACACGTGTGTATGTATATTTATATACACGTGTGTATGTATATTTATATACACGTGTG +TATACACATGTGTATATATACACATGTGTATGTACATATATTTATATACGCATGTGTATT +TACATACATTTATATACGCATGTGTATGTACATACATTTATATATGCATGTGTATGTACA +TACATTTATTTATGCATGTGTATGTACATATATTTATGCATGTGTACGTATATTTATTTA +TGCATGTGTATGTATATATATGCATGTGTATGTATATATATACATGTGTATGTGTATATA +TATGTTCAAATGTATATGTATATACATATAAAATATATATATTTGAACTGGATTTCACTG +ATTTAAATTTAAAATATATATACACACATATTTGAACTGGATAATTTCAAATATATATAT +TTCATATATATATTTGACTTGGATAATTTCTTCACTGATTTAAATTTAAAAAAATATATA +CATATATGTATATATATACATATATATACACACACACATATATATACACATATATATATA +TATATATATTTTTTTTTTTTTTTTTTTTTTTTTTTTTGAGACAGAGTCTCACTCTGTCGT +CCAAGCTGGAGTGCCATGGCGCGATCTTGGCTCAGTGCAACCTCCATCTCCTGGGTTCCA +GTGATTCTCCTGCCTCAGCCTTCCAAGTAGCTGGGATTACAGGCATCCAACATCACGCCC +GGCTAATTTTTGTATTTTTAGTAAAGACAAGGTTTCACCACTTTGCCCAGGCTGGTCTCG +AACGCCTGACCTCAAGTGATCTGCCCGCCTCCGCCTCCCAAAGTGCCAAAGTGCTGGGAT +TACAGGTGTGACTCACCGTGCCCAGCCCCAAATATTTTTAAAATAATAATATTAAAAAAG +CAAACAGCAGTAAAAAATTCATAAAGATAAAATGACAAAACTAATAATTGGGAACAAGAA +ACAAATTCAAGGATTAGGTTAACAAATCTTCAGGGAGGCCAAGGTGGGAGGATTGCATGA +GGCCAGGAGTTTGACAAGACAGGCTGGGTGACATAGCAAGACCCTATCTCTACAAAAAAT +AAAAAGAGTTAGCCAGGTGTGGTGGTGCGCACCTATAGTCCCAGCTAGTCAGGAGGCTGA +GATGGGAGGATTGTTTGAGCCCAGAGGTTCGAGGCTGTAGTGAGTTATGATCACACCACT +GCACTCCAGACTGGGCAACAGAGTGAGCTCCTCTCTCTAAAAATAAAAATAACAAATAAA +AATGAATCTTTTATTCGAGAAAACATAAATGTACAAAATTGAAATTAGAAAGAAGTCATT +TGGAGGCAGTTTTAAAAGCAAATAGTATATAGAACCCTTTACAGTAGTGACACTGGGAGT +ATTGAAGAAGTGCTTGATCCTTCTAGGGAAATCGGTGAGATGTTGGTTGTTGTCATCAGA +AGAAATAGAAACCTTTTGTTTGACAATAACTATGAGAAAAACTGAAAATGTTACCAAAGG +CTTATCTTGTAGAAAGGCCCTGGTTTGGGCAATTTTAAGGGAAGTTCTGTTAAATTGCTC +ATGATGAATTAATTTCCCTGCTGCATAAACTGTCACAGAGCCTAGCAAAAGATGAATATG +TTCACTTATTTTAAGAAACTGTTATAATCTTGACACCCAAACTTGATTTACAGGTTTGAT +TGTGTTTACATTTGGATTGAGAAAGCCCTCAAATACAGGATGTTAATAAGGCAACTCTAG +CCCTGTAGTAAAGAAATAAATAGTGCTTACACTAAGAAAGCAAAGATAGGTTATTATTTT +AAAACCTATTAATATCATTCAACACATTAATATGTTAGAGAAAGTCAATGATAAGATCCT +TTTAAAATAAAAACTAAACATATAACAAAAAGAATTCCAGGCCGGCCACGGTGGCTCATG +CCTGTAATCCCAACACTTTGGGAGGCTGAAGCAGGTGGATCACTTGAGGTCAGGAGTTCG +AGACCAGCCTGGCCAACATGGTGAACCCTGTCTCTACTAAAAGTACAAAAAAAAAAAAAA +AAAAAAATTAGCTGGGTGTGGTGGCAGGCACCTGTAATCCCAGCTACTCGGTGAGGCTGA +GGCAGGAGAATCACTTGAGCTCGGGAGGTTAAGGTTGCAATGAGCCGAGATGGCACCACT +GTGCTCCAGCCTGGGTGACAGAGCAGGACTCTGTCAAAATAAATAAATAAATAAATAAAT +AAATAAATAAATAAATAAATAAAAATCCACATAGATTATAAATATAGAGGTAAACATTTA +AAACATAGAGAAATCTTAGAAGAAAGTAGATGAAAGTTTCTCAGCACTGCTGCTATCTGG +GACTGGAGGGTTCCATGTGGTGGGGTGTCCTGTGTACTGCAGGGTGTTGAGCAGCGTCCC +TGGGCTCCGCCCACCAGATGCCGGCAGGAGTTGGCAGTTGTGACAACTAAAAATATCTCC +ACATGTTGATGAAGGTGGATGTTTTGTTCATCTGAAAGCTGGAAATGCTGGTGTAAATTA +AACAAGATGGAAGAGGACACCAGAACTGCTGTGTGTCAGAGATATTATGTGTTAAAGATA +AAACAAACTGAGGGCCACATTTAAAATATTATAATGGAGAGGTTCTTATTGTCCATCACG +TACAAAGAACTCTGAAAACACTTTAGGGGTTTGCACGGGCTCGTCTCTAGCACGCCAGAA +GCAAAGATAGACAGACAAATACAAAAATAGGTATTAAACACGAGCAACTGGCTGGGTGTG +GTACCTCACGCCTGTAATCCCAGCACTTTGGGAGACTGAGGTGGACGGATCACTTGAGGT +CAGGAGTTCGAGACCAGCCTGACCAACATGGTGAAACCCCGTCTTTACTAAAAATACAAA +AAACATTAACCAGGCGTGGTGGCGCCTGTAATTCCAGCTACTCGGGAGGCTGAGGCAGGA +GAATCGCTTGAACCTGGGAGGCAGAGGTTGCAGTGAGCCCAGATCGCGCCACCTGCACTC +CAGCCTGGTGACAGAGCGAGACTCTGTCAAAAAAGAAGGGAAAAAAAAAAAACCTGACTA +TATTAAGGTCCAAAAATGCACCAGTGAGTGGAAAGGTACACATAGCACATCCAGCAGGTT +CCGTGTTTTATTTTAAAAGCCGGCGGGGGCGACGGGGTAGAAAAATGCTGTTAAAGAGTG +TAATTGAGTTGCTTGTAACACAAAGGATAAATGCTTGAGGGGATGGATACTGCATTTTCC +ATCATGTGATTATTACTTATTCCTGCCTGTGTCAAAGTAGACTTAAGGTTCACTCAAGAG +GAACTTTAAAATATTCAGAAACAACATGGCAGAAATCGTGGGAAGGTTCAGTGTTGCAAG +TCGGGTTGAGGTTTTGTGGGACCTTTTATTATATGTTTCGTAGTCATGGGGAGAATTGAG +GGATGGCGCTCTGCGGTGGTCAGGGCAGTGGAAGACGAGCAGTGAGCAATGACCGTAAAT +GACCAGGGGTGTGGGTGGTGGGAGATCGCCCCTCCCCCAGGCTGTGTGGTACAAGCGTGT +TATGGAGTGATCTTGCAGGGAAACCTGCTTTAAACTAATTGTATTCATGAAACATAATTC +TGCTTCCAGGAGTTTATTTTAGGGAAATGAGCAGAGCTGAACAAAAAGATGTAAGGACAT +AAATGGCAGTGCCATTTGTAGTGAGGTGGAGTGCTGTTTCTCTTGCCCTCCCCCCAGCCC +GGATCTTTACGCAACTGTGGTGAAGATGCCATAAATTCCATAAATAACTGGGCCAAAAGC +AGAGGGAGATTTGCTGAAGGAAGGGTACTTTTTCAGAGAAATAGTTACCTTAAATACAGA +GCAGTGAAATCTTACAAATAAATGTCGAGTCCAAGAGAAATGCTAAGAGATAGAAAAGGT +CCGAGAGCTTCAATATCTGTCAAATAGGAGAGAAAGAAAAAGAAAGAAAGAAAGAAGTAA +CTCCTATTATATTTCAGCTCTGAGACAAAGTTTAGATTGAAAGTGTTCCAGATATTGAGC +AGAGTGGATGAAGAAAGCTCAAATGTAGACACCAAGTGGTAAAATTTCAGAGCAGCAAAA +ATGAAGAAAAATCCTAAATGCCTTTCTGTATCAATCTGGTTGTGACAATTGATGTCTCAA +AATTCTGGTGCAAGATAACTTTGAAATGAAAGTTCTGTATTCAGCTTTAGTACCGTAATT +TGAAAGCAAAACAAAGACTTTTCAAATTTGCAAACGTTAAAAATGTTATCCCTCAAAGAT +CTTTGAGGAAAAAGTTAGTTGATTGACTCCTGCAAAATGGAATGTAATCCAAGAAAGGCG +AGAGTAGCCAAGCACAGTGGCTCATGCCTGTAACCACAGCATTTTGGGAGGCTGAAGTGG +GAGGATCGCTTGAGTTCAGGAGTTCAAGACCAGCCTGGACAACATAGTGGGGTCTCATCT +CTACTAAAAAATTTTTAAAAATTGCTGAGTGCAGTGGCACATGCCTGTAGTCCCAGTTAC +TCAGGAGGCTGAGGCGGGAGGATCACTGGAGCCTAGGACATTGAAGCTGCAGTGAGCTAT +GATTACACCACTGCACTCCAGCCTGGGTGACAGAGCAAGACCCTGTCTCAAAATAATAAT +AATAATGATAATGATAATGATAATAATAAATAGAAGAGAGCACACAGGAAGCAGTGCTGA +ATAAATAAATGTATAAAACAGAGTTAAGTCTGAATGTGTTAGTGCACAGTTACGAAAATA +ATCTGGAATTAACATTTCACATGGGAGGTAATTGAAAGAGCAGAGAAGAAAGAATGAGCA +TATGTTCATGTTTTTGTTTCGTCTGGGAAGAAGACATAGGTAATGACTATATTTGATAGA +AAATATAAGCTTAAATACGTGTGCTGACAGTTGAAAGGTGGTTACCACCAGAAAACTAGA +AAAGATGTGTACAAGTTTCAGAGCCTTAATGGGAAATGCGTGGATTGAAGAAAACCTGAT +TCATGCAATCAGAGGTGGGTGGGAAAGAATTACACTGATGTCAGGCCTCTGAGCCCAAGC +TAAGCCGTCATATCCCCTGTGACCTGCATGTACACATCCAGATGGCCGGTTCCTGCCTTA +ACTGATGACATTCCACCACAAAAGAAGTGAAAATGGCCTGTTCCTGCCTTAACTAATGAC +ATTATCTTGTGAAATTCCTTCTCCTGGCTCATCCTGGCTCAAAAGCTCCCCTACTGAGCA +CCTTTCGACCCCCACTCCTGCCCACCAGAGAACAACCCCCCTTTGACTGTAATTTTCCTT +GACCTACCCAAATCTTATAAAACGGCCCCACCCCTATCTCCCTTCGCTGACTCTCTTTTC +GGACTCAGCCCACCTGCACCTAGGTGAAATAAACAGCCTTGTTGCTCACACAAAGCCTGT +TTGGTGGTCTCTTCACACGGACGGGAGTGAAAACTGAAGAAATAGAAAATCTGATATATG +TAAAAAAGGGAAAATAATATAAAATGAAACTGCAGGACTCAATCCAAATATAACCGTGAT +CATAATAAACATGAATAGATTAAAATTCCTTTTTAAAAAGATAGGCTTTCTGAATGGGAA +AATAAACATAAAATCCGGACATACAGTAGTGTAGGAGGCAGCTTAATTAAAAACAAACAA +AATGTTGAAAATAAATGGATGCATTTGATATGATTCTGTTCCACTATCCAATCTAAGTAA +TGGTCAATTGTTTTATAGATTGTTCTTCAGTTGTTTGTTGTTGTTGTTGTTGTTTTGAGA +CAGAGCCTCGCTCTGTCGCCCAGGCCGGAGTGCAGTGGCACGATCTCAGCTCATTGCAAC +CTCTGCCTCCCAGGTTCAAGCAATTCTCATGCCTCAGCCTCCAGAGTAGCTGGGATTAGT +TTCCCGCCACCGCACCCGGCTAGTTTTTGTATTTTTAGTAGAGACGGGGTTTCACCTTGT +TGGCCAGGCTGGTCTCGAACTCCTGATGTCAGGTGATCCACCTGCCTAGGCCTCCCAAGG +TGCTGGAATTACAGGCATGAGCCCCTGTGCCCAGCCTTCAGTTTGGTTTTGTCCAGTGTT +TTCTCATGATTAGACTGAGGTTATGCATTTTTGGCAAAAAAATCATCAGAATTGATGTAA +GTTTTCAGTGTGTCATGCTATGGAGTGCATGATGTCTGTATGTCCTGACCTGGTGATGTT +AAATTTCATCACCTGGATTAAGTGGTGTCTGTTGGAATTCTCCACTGTGAAATTATTATG +TTTTTCTTTTAGTAATGGAAAATATCTTGGCATAGACATTATACAAACAGCCTGTTTCTT +CTCTAAAAATCAGTGAGTCTTGTCTGCAACAGTTGTTACTATAGTGTTTGCCTAATCGTG +GTTTTCTACTTCCCTCATTCCTTCTATTTCAATTACTTGGAATTATCTTCTAAATTAAAC +CTGCCCTTTCTTTCTCACATATTTGTTTATTCAATAGTTATATTAGGTCAGGCGTGGTGG +CTCATGCCTGTAATCCCAGCACTTTGTGAGACTGAGGCAGGCAGATTGCTTGAGCCCAGA +AGTTTGAGACAAGCTTCATAAACATTGTGAAACCCCATTTCTACCAAAAAATACAAAAAA +TTAGCCGGGCATGGTGGCATGCACTTGTAGTCCCAGTTACTTGGGAGGCTGAGGCAGGCG +GACCACTTGAGCCCAGGAGTTCGAGGCTGCAATGAGCTATGATTGCACCACTGAACTCTA +GCCTGGGTGACAGAGTGAGACCCTGTATCAAAAAGAAAACTTATATTAGTGTAGGCTCAT +GAATATTTATTTCATATTTTGGGCTTGTTGTTTTTTGTTATTGATTACATTATTTCAGCT +TTGGCAATTGGGTGCTTCCCCTAGCTGGCCCCCTGTATTCTTTCAATATGCCCCCATCCT +TTTCTAGCACTTGCTTAATTTTTCTGTCATCCCAATATGTTCCAGACTATGATGAAGTGG +GATTTAAGCAAAAATAAATAAATAAATGGAACAGAGCAAATTTCACTTTGATAAAATGGA +CAGTCTTTCAAGCTTCGAGTCTCAAACTTGTATGCAACTAACAATGTAAGCTTTGAATAC +AGAAAGTAAAAATTGATAGAGATTGTTATGGACATCTGTTAGTTTCTACCAGCTCAGCAT +TTACATTTCTCTGCCTCTGCAGCTTACAGAGGGAAACTGTCTTCCTAAGAGCTGGCCCAA +GTGCATGCATCTTAAGACAGTTCTGTTCAATTTGTCACATTTTTCAAGTATGCATGCATT +TCTTTTTCATAATATTAATATTTATTACTATATATGAATACTAGATTGAAAGCCCAAGCA +TTCAGTTTACACACAGAAATTATGCAATTATATATCGCTTCACAAAGGCAGTGAACACAT +TACATTCTACAAAATCTACTTCACAGAAATTTAAAAATTCTAAATATCAAAAGGTACAGC +TGAAGAAACAGGTATAAATTTGGCAGCCAGTAATTTTGACAGGGAAGTTGCAGCTTGCAT +GACTTTATTTTTTTGTTTGTTTTTTGAGACAGAGTCCCACTCTGTCGCCCAGGCTGGAGG +GCAGTGGTGCCATCTCGGCTCACTGCAACCTCTGCCTCCTGGGTTCAAGTGATTCTCCTG +CCTCAGCCTCTTGAGTAGCAGGAATTACAGGCGCCCACCAGCACGCCTGGCTAATTTAAA +TTTTTTGTTTGTTTGTTTTTGTTTTTTTGCTTGTTTGTTTTGAGATAGAGTCTCGCTCTG +TTGCCCAGGTTGGAGTGCAGTGGTGCGATCTCAGGTCAGTGCAATCTCCGCCTCCCGGGT +TCAAGCGATTCTCCTGCTTCGGCCTCCTGAGTAGCTGGGACTACAGGCGCCACCACACCT +GGCTAATTTTTGTATTTTTAGTAGAGAAGGGGTTTCACCATGCTGGCCAGGCTGATCTTG +AACTCCTGACCTCAAGTGATCCGGCTGCCTCGGCCTCCCAAAGTGCTGGGATTGCAGGCA +TAAGCCACCGCGCCAGGCCTTGCATGACTTTAAATATATGAATATGAAAATATTGAACTT +AGAGTAATCATTGTGCTTTGTGTTGATTGAAAAATATAACAATGGCTATCAAAGAAGCAT +GTTCAAAGATGCTTAATTCACTTCAAAATGTCATACAAATTGTGGTGGTTTCTATGCACC +TCTAAAGCTTCCGTCATTTAGCTCAGGTACATTACTAAAGTAATATATTAATTCTACCGG +TACAGTGGGGTTTCACACCATTGGCATTTGCATTCAAGCATGCAGAGGCTTTTGGGCACA +AGTGGACGGTGTGCACAGCTCTAAGCCATCCGTGGAAATGTGCTCTGAACATGGAGACCG +CAGTGAGGGCTGTGGGGATTCTCTTTGCATTCCACGTTTGTGAGCAGCAAAACAGCACCC +TCTTGAAGGAGGAGGTGGTTCTGTGCTGAATATTCACCCGCTGTCCCACTATTTGGCACA +TGTCTGTTCCAGGGTCATCCTCTCGAAGGTGTTCGATGAAGTCATTGAAGTGAATCTAAT +CGATAGTGCCGACTACATCCACCTGGCCTTTCTGAAGAGACCTGAGCTCGGGCTCACCCT +CACCAAGCTTCACTGTTGGACTCTCACTCACTACAGCAAGTGTGTCTTCCTGGATGCAGA +CACTCTGGTGAGTGAAGACTCTCTGCTTGATAGGAAACCCTCCAAGACCACATCTCTATC +CTTAAGCAGGCTGTCAACTTTTTTTTGTGTGTGTGTGACACAGTCGCTCTGTCACCCAAG +CTGGAGTGCAATGGCACGATCTCGGCTCACTGCAACCTCCGCCTCCTGAGTTCAAGTGAT +TCTCCCACCTCAGCCTCCCGAGTGGCTGCTATTACAGGCACCCGCCTTCATGCCCGGTTA +ATTTTTGTATTTCTGTACAGACTGGGTTTCGCCATGCTGGCCGGGCTGTCACCTCTTACT +GGTAGATTCCTGTGAGGCCATGTGCATTTCTATTTCTAACACAGATGTTCAGTCTATTAT +AATCAGGCATAACATACCCCCGAGCACTGTGCTAGACCCTGCTGAAGAGAACAGGGGATT +GGAAGACATGTTCCTACCCCAGGAATGAATTATAACCACAGTATTTTACACGCACAAAAT +AGAATCATGAGGGAAAAAACTTGTGACTGGGCACAGTGGCTCATGCCTGTAATCTCAGCA +CTTTGGGAGCTTGAGATGGGTGGATCACTTGAGGCCAGGAGTTTGAGACCAGCCTGGCCA +ACACGGTGAAACCGTTTTTACTAAAAATACAAAAATTAGCCAGGCATGGTAACAGGTGCC +TGTAATCCCAGCTACTCAAGAGGCTGAGGTGGGGGGATCGCTTGAACCCGGGAGGCGGAG +GCCGCAGTGAGCCGAGACTGAAGCACTGCACTCCAGCCTGGGCGACAGAGCAAGACTCTG +TCTCAAAAACAGAAGCATTGGTAAAAGAAGCATTGCGGCGGGTTCTGCGTGTTTTGCTTC +ACCAGGTGCTGTCCAATGTCGATGAGCTGTTTGACAGGGGAGAGTTTTCTGCGGCCCCGG +ACCCCGGATGGCCGGATTGCTTCAATAGCGGGGTGTTTGTCTTCCAGCCTTCTCTCCACA +CGCATAAACTCCTGCTACAGCACGCCATGGAACACGGCAGCTTTGACGGTAAGTCAGGGC +AGCCCGGACGCTTAGGGTCTCTGTTGCACACACTCAACTCTGCAGATGTAACACGAAGTC +AGCCGTTGACCATACAGTCACACCTCGCTCAGCGACAGGGATGCGGTCTGAGAAATGTGT +TGTTAAGTGATTTTGTCATTGTATGAACGTCCCAGAGTGTATCTGCACACACCTGGATGA +TGTAGCCTACTGTATACCTAGGCTGGAGGGTACAGCCTATTCCTTCTAGGCTACAAACCC +ATATAGCATGGGAGTGCACTGAATGTTGTAGGCAACTGTAACATAATGGGAGGTATCTGT +GTTCTAAACATACCTAAACATCACAAAGGTCCAGTGAAAATACAGTATAAAATCTTATGG +GACCACCGTCAGATGTATGGTCTGTCTTTGACCGAAGCACTTTTATGTGTTGCATGACTG +TACTTGGCATTGAACATGGGCTGGCCGTGGTGGCTCATGCCTGTAATCCCAGCACTTTGG +GAGGCCAGGGCGGACAGATTGCTTGAGGCGAGGAGTTCAAGACCGGGGTGGGCAGATGGC +TTGAGACCAGGAGTTCAAGACCAGCCTAGGCAACGTGGCAAGACCCCATCTCTACAAAAA +ATACAAAAATAAGCTGGATGTGATGCTGGCACCTGTAGTCCCCAAGCCCTGGGAGGCTGA +GTTGGGAGCAGCAGCTGAGCTCAGGAGCTCAAGCCTACAGTGAGCTATGATTGCACCACT +GCACTCCAGTCAGGTTGACAGAGTGAGACCCTGTCTCAGAGAAAAAGAAAAGAGCATGGC +TGTGTTCCAATAAAACTTTATTTATAAAAACATGCACAGTGTGTAGTTGCTTGACCCATG +GTAGAATATAGGGAGAATTAAAAGGAGGCAACCTGAAGCCGAGTATTTGTTGAAATGGGC +GTCAGTAGAGAGGAAATGTGCTGGAATTTTTGTAAAGTAAAAGAAAATACTGGAGCAGTG +AAGAATTGCCTCTAGGTAAAGGGGAAGTTAATGAAACTGGCAAAAATGATGGGAAAAGCA +TTGTCACTACCAGGGAGAATTCATTAGGGGACCAGTGGAATGCTTTGGACTCCATATGCA +ATTTTAGCATTCATTCTGGGGACTCCTGGTGGAGAATTTTGGAGGGAATATGCACTTATT +TTTATCAATGGCTTGGGTTATCAGTCTTTTCTGAGAACCAAGAGAATGTGTGCAGCTGGC +AGACAGAAGAAATGGAATTAGTAACCCTGAAGGCAAGTGTTTATGTTGAGAGCTTCAGGC +ACATCTCGCATTCTTGGAGTGAACCAAGCCATACTTTGCTAACCTGCTTTTGTGTTTGCT +CATTATGTAGGGGCAGACCAAGGCTTACTGAATAGTTTCTTCAGGAACTGGTCGACCACA +GACATCCACAAGCACCTGCCGTTCATCTATAACTTGAGTAGTAACACGATGTACACTTAC +AGCCCTGCCTTCAAGCAGTAAGTTCTCCACCCTGGCGAATCCTGCCAGATCTGCCACTAC +CGATCCACCTTCCCTCCTGGAAGACATACCAGCTGTCGGCATATTTAAAAACTCTATCTA +TCTATCTATCATCTATCTATCTATGTATCTATCTATCTATCTATCTATCTATCTATCTAT +CATCTATCTATCATCTATCTATCTATCACCTCTATCTAGGTAGATCTAAATATCTATTTA +TCTGTATAGATAGATACCTATGTCTATGTGTCTGTGTATCTAGATCTCTATGTCTATCTA +TATAGATATATATCTGTCTATATAGTTATCTACCTATATAGGCCTAGACATCTGTTTATC +TATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCCATATCTATCTATTTA +GATCTGGATATCTATCTGTATACATAGATCTATATATCTATATCTATATATGTATCTATA +TCTAGATCTAGATATCTATATACATTGATCTATCTAATCTCTATATCTATGTAGATATTT +ATCTATCTATCTAGACCTAGATGTCTATCTATCTAGACCTAGATATCTATCTATCTAGAC +CTAGATATCTGTCTATCTGTCTAATCTATCATCTATCATATGTATCTATTCAGATAGATC +TGGATATCTATCTATAAACATCTTATCTATCTATCTATCTAGATCTACATCACTATATAG +ATACCTATATCTATCTATCTAGAACTAGATATCTATGTATCTAGATATCCATCTAGATTT +AGATCTTCATCCATATAGATATCTATATCTATCTATCTAGATCCAGATATCTATCTATAT +ACATAGATCTATATATCTATATCTGTATATCTATCTAGATCTATCTAGATATCTATGTAT +ATACATGGATCTATATATCTCTCTATGTATCTAGATCTAGATCTCTCTCTATATAGATCT +ATGTATCTAGATCTAGATCTCTATATAGGCATCTATCCATCTATGTAGATCTAGACATCT +ATCTATATATTAATACATAGATGTATCTATCTATATACGTCTTTATATATGTATATACAC +ACACAGAAACACACACACACATCTCGTTTCCTGCTTGCTTGTTGCTGTAAATGATAGCTA +GCCAAGGCTCTACGACAATGATCCCCAAAGTGTGGCCCAAGGAACCCTGACCCCACAACT +CTTTCAAGTGTCTTCAAAGTCATAACTACTTTAAAAAAAGAATTTGAAGATGTGATTTTT +TTCCCTTTTTGCTGCCATTTTCTCATGCATCTATGCTGAGAGTTTACAGACACTACATGG +CATGTGATAAGGTAATACCCTGAACACAGATGGAGCTAGGAAGAACCAGCTGTCGCCTCT +TGGGAAAATGGATGGCACTCTTCTCACAATGATTTTTTTTAATATAGAAATTTTTTTAAT +GAAAAATTATGAAATTTATGTTACTGCATAATGGTTTGATTTTTTTTAAAGGGATTGATA +AATATGCTTTCTAATTTCTCAGTTTTAATATCGATTATTCTAAATATGGAGAGAGAGAAT +CCACAGGGACATGGCCGAGCACAGTGGCTCACGCCTGTCATTCCAGCCCTTTGGGGGCCG +AGGTGGGCGGATCACTTGAGCTCAGGAGTTTGAGACCAGCCTGCGCAACATGATGAAACC +CTGTCTCTACGAAAAAATAAAACAAAACATTAGCCGAATGTGGTGTCGCACACCGCTAGT +CTCAGCTACTCGGGAGGCTGCGGAGGGAGGCTCACTTGAACCTGGGAAGTGGAGTTTGCA +GTGAGCCGAGATCGTGCCACTGCACTCCAGCCTGGGTAACAGAGCAAGCCTCAGCTCAGG +AGAAAAAAAAAAGAAAGAATCCACACGGACAAAGCTCTTTGGGTTCCTAAAAGGGTCAAG +GGTGAGGGGACCAGAGGCTGTGAAATTCACTGCTCCAGAAGATATGGCTATAAATGAAAA +TAGAGAATCTGAGAATCACCTTGGGAATGAATAATTCTAGAGTCTGCATTCTCTACAGAG +GACACGGTGTCCCTAAGGAAGAGAAATTGATTCTTGGGAGTGAAATCTTGTTATTTTTTA +CTGTATAATCACAGATGTAATGTACAGAACATAGATATGTCATGTGACTTTTGTGTTCAT +ATTTCATGAGGAGGTGATCCACGAAAAAAAAGTTTAAAAAGGCTCCTGGAGGATGGTGAT +GATGAACAACAAAAAAGTTGGCAAGGGGAACATTTAGAATCCTGTAAAAGAGAAAAAAAG +CCAATTGCCTTGCCGCTTGCATTAGCCACTGTAAAAGCTATTTTTTTTTGCCCCTGTCGT +TTTAAGGATATGATGATTTGGGCTGCTGTACTTCACGTTTTTACAAAACTGATTTATTTT +TCCCGTTTTGGGAAAAAATGTCAATGGATTACGATTATGTTTTTTGATATATAGAAAATA +AAATAACTGCAAAAACTGTGATTTAAAAAATATATCTTTATGCAAAATAACTGCAAATGA +AACTACTACTACTATGCTGATAGCAGTGGAGTAGTATTATTGATGATATATTGATTACTA +TCTTGATAGTAGTGGTATGCTAGTATTGCTCAGATATTGATTACTGCATTGATAGTACTA +GTATATTATTATTGATTATATATTGATTACTATAGTAGTGATAGTATTTTGTTATTATTG +ATCACACATTGATTACTGAATTGATAGTAGTAGTATGTTACTATTGGTTATATATTGATT +ACTATGCTAGTAGTAGTATATTGTTGACTATATATTGATTACTACATTGATAGTGGTAGA +TTATTATTGATTATATATTGAGTACTATGTTGATAATAGTAGCATAGTATTGATTACATA +ACGATTACTACATTGATAGTAATATATTGTTATTGATCATATATTGATTACATGCATTGA +TAGTAGTAGTGTATTATTATTGATTATATATTGATGACTATGTTGATAGTAGTAATCTTA +TTATGGGTCATATATTGATTACTGCATTGGAAGTAGTAGTGTATTATTATTGATTATATA +TTGGTTACTATGCTGATAGTAGTAGTATCATCAGTAATAATAATCAATAATGGAAACCCA +TTGGGACAAGTCCTTCAGAGGCTGTCTTTGAGGAGCCCCATGGTAGGTGGATGCTTTCTG +GGTGTCTTTTATCACATCTGAGTGGAAATCAGAATCCCTTCTGTTTCCTTCTCAGATTCG +GTTCCAGTGCAAAGGTCGTCCACTTTTTGGGGTCCATGAAACCTTGGAACTACAAGTACA +ATCCACAGAGTGGCTCGGTGTTGGAGCAAGGCTCAGCGTCCAGCAGCCAGCACCAGGCGG +CATTCCTTCATCTCTGGTGGACGGTCTACCAGAACAACGTGCTGCCCCTTTATAAAAGCG +TCCAAGCGGGGGAAGCACGCGCGTCTCCTGGTCACACAGTAAGTGGGGGATTCCCTTAAA +ACCCGTAGCTGAGGACGAGGAGAACATCCTTGTCACCAAGGTCTGGCGTGGTTTTTTTTT +GAAATGCCCCTTTTTTGTCTAAATACTGTATTTCATGGAAAAGAATACTGAGAAGCAAGC +ACCTGTTAAAAAAATTTTTAAGTTTTAGCTCAAAATAGAGAATGCCTAATGACTGGAGAT +CCTGTTTTGATGTGTAGGCCTGGTGCAGAAATAGGTTATTGAAATTAGCCATCCTCATCA +GAGTAAGAGACACTCATGGACAAGTGGTTCACAATGACTGATTACGACGTCATTCGGGTC +AACACTTTCCACTTGAAACCATCATTTGAGATAGCAGTTGGAGGAAGTGTCTGAAGAGGA +TTTTGTAAAGTTTTGATTGACACCAATTTGATTGCAAAGAATATAATGACAGCCCCTCGG +TGTGCTAAATGGTGGAGTATCTGCAGTGTGCTGAATGTAGGCTGCATCTGCCTTGCAGAA +GACCTCTTGCAATTAGGACTCAGGAAACTTCTTATTCCTAATGGCTTTTTTCACTAAAGT +AAAAAAAAACTTGAGCTTTTTTTTTTTTTTTTTTTTAACTAGAGCATTTGTACTAGAGTA +CCAGAGTATTTTTTAACTAGAGTAAAGAAAACTAGAGTTTTGTTTGTTTGTTTGTTTTTT +GAGACAGAGTCTCACTCTGTTACCCAGGCTGGAGTGCAGTGACATGATCTCGGCTCACTG +CAACCTCCGCCTTCTGGGTTCAAGCAATTCTCCTGCCTCAGCCTCCCAAGGAGCTGGGAT +TACAGGTGCCTACCACCACGCCCAGCTAATTTTTGTGCTTTTAGTGGAGACGGGGTTTTG +CCACGTTGGCCAGGCTGGTCTTGAAGCTCTGACCTCAAGTCATCCACCCGCCTCAGCCTC +CCAAAGTGCTGGGATTACAGGCGTGAGCCACCAAGCCCGGCCTTTTTTTTTTTTTAACTA +GAGCATTTGCTAGTACAACAGAGTCTGCTATCAGCACATGCATTGCCTGGGAAATTGAAA +AGAATCCCTATTTTAATTTTTAGTATGGTTTTTTATTTGGGTGGATCTAGGCTGCTTTTT +AAGGACTGCTGAAAATTTCTCTCACCGAGTGACACTAGCAATGGACGTTTATTTGTATTC +ACTTCACAAACATTGACTTGTCACATATTTCCTGCTGGGCGTTTTGCTAAGTACTGGATT +ATTAAGTACTGGATTACTAAGTACTGGATTACTAAGTACTGGATTGCATAGGAGGGAATT +TTAAGGCTTAGTGTCAAACGGTCCTGAGAAAGAAAACATTTAGGACAATTATTTAATGAT +TGGCAGATGGGAGCTGGGAGCCCTGGCTACACAGGGCCCCACCCGCCCCCCAGGACAGCA +GGTGAATTGAGGAGACATAGGGAAGACTCACTCCACGTGTGTGTTTTTGTGCAGCTTTGC +CACAGTGATGTGGGGGGGCCGTGTGCGGATTCAGCCTCTGGTGTTGGAGAGCCGTGTGAA +AATTCAACACCCAGTGCGGGCGTGCCGTGTGCAAATTCACCACTGGGTTCTAACCAGCCT +GCTCAGGGCCTTCCGGAGCCGACCCAGATAGTGGATGAGACCCTGTCCCTACCTGAAGGA +CGCCGTTCAGAAGATGTAAGTACCTGCATTCCTCACAGGTGTGATAGTCAGACGCTGGCT +CGCAGTGAGAGAGCAGAGAGAGCCGGCTTCCCTGGCTCCCTGGGGAGGGGAGATGGAGGG +GAAGGGCTGGTCTTTGGCTTGCTGTGGCATTCAAGGCTCTGCATTTATTTTTGCATTACG +GCACACCGAATCAAGCTCACCTGCTGAAAGATGTCTATGCCCCAATCCCTAGGACCTGTG +AATGTCACCTTGTGTGGCAAAAGGGCGTTTGCAGTTGTGATTAAATGAGGGACCCTGAGC +TGGGGAGGTATGGTCTTGGATTCTGGGAGTGGGCTCTTAGTCATCACAAACCTCCCTTCA +AAGAAGAAGGTGGAAGTGTGAAGGTCAGAGAAGGAGTGTGAAGCTGGAAGCAGAGGCCAG +AGAGAGAGGGGATTGGAAGACGCTGGGCTGCTGGCTTTGAAGATGGAAGAGGAGGCCACG +AGCGAGGGAATATGGTGGCCTCCAGAAGCTGGAGAAGGCAGGAAATGGATTCTCCCCTAG +GTCCCCAAGAAGGAACCAACCCTGCCGACAACTTGATTTTAATCCACTGGACTTCTGGCC +CCCAGAACTATCAGATGGTCAGTCTGCCTTGGTGTAAACCACCCAGTTTGTGGCTGTTTC +TTACATAGCAGCCTCAAAAATCTGATGCCACAAGGAGACAGATGCTCAGTCTCTCGCAGT +TTACAGATTCTGGGGGAGCCAGAGCTCTTTCAGGTTCAAAAAGGGAGGCTTCCGTCAGTG +CCCCCTCAACCCAACTGCCTGGCCGTGCATCCTGAGAGGTTTCAGCCGAACCCCTGACTT +GAACAGTGGTTGAAGTGAAGATGAATTCCTGCCGGGGTTCAATGTTCAAATGAATGTTGA +CCTGCACAGTGGTGTCTGCTGAGGCCGAGTCTGCAGCACTTTGTCCCCATCGAAGAAAAA +TGAAAATACACCTTACTTGCAAAACAAATAATGGAGGCCGTCATTTCTCCAGCTCCAATT +TCTAGGTGAATACTTTGGAATAATATCTTGTGTTTAAAGATTTCCTGGGGCCAGGCACGG +TGACTCAACACCTGTAATCCTAACACTTTGGAAGGCTGAGGTGGGAGGATTGCTTGAGCC +CAGGAGTACGAGACCAGCCGGCAACACACTGAGACCTCATCTCTACAAAAAAAAGTCAAG +AAATTAGCCAGGCATGGATGTGTGCACCTGTAGTCCCAGCTACTTGGGAGGCTGAGGCAG +GAGGAATGCTTGAGCCTTGGAGGTCAAGGCTGTAGTGAGCTATAATCTCACCACTGCACT +CCCGCCTGGGTGACAGAGCGAGACACTGTCTCAAAGAAAAAAAAAAAGAAATCTTTTTTT +TTTTTGAGGCGGAGTCTCTCTCTGTCACCCAGGCTGGAATGCAGTAGCCCAATCTTGGCT +CACTGCAAGCTCTGCCTCCCGGGTTCACGCCGTTCTCCTGCCTCAGCCTCCCGAGTAGCT +GGGACTGCAGGTGCCCGCCACCGCGCCCGGCTAATTTTTTGTATTTTTAGTAGAGACGGG +GTTTCACTGTGTCAGCCAGGATGGTCTCGAACTCCTGACCTTGTGATCCGCCTGCTTCGG +CCTCCCAAAGTGCTGGGATTACAGGCGTGAACCACCACGCCCGGCAAGATTTCTTGTTTT +AAATCTTTACCACTGATCCTAACAAGTTTCTCAACAGAATTATTTTGAGATCATACTTAG +GGAAGGATCTGGGGACTGGGCTGAAGGAAAGTGATTCTTTTCTGTATACTTCAGATAGCT +CCGGGAGAGCCGTTTCTTGTTGCTTATAAACAAGTGACCTTTAGATTTTGCACACATTGC +TCTGGAAGACACCACACGCTTCACTGTACTCTGGCGTAAATTATGCTCTGGCAACTTTAT +GCATGAAGAATGTCGGAGTGGTGATTTCACATTGACCCAAACACATTGAAAAGATGTTTA +GGTTCAGATGGTGAAGACTGAGGAGGTGTAAAATGCGCTTTTCTGGTTTTTCATTCCTCA +TGGTGTGCCCTGAGCATACCATAGCCTGGGCCTGGCCCCAGGACGTGCCTCATGCGAGTC +AAGTCAAGAGCCTCTGCTTGTTCCTGCTGGAATGTGAAGAATTCCATCAGTGGAGCCCTT +ACATGATGTGCAAAACGGCTGCAATTGTGCTGAGCCATGCTCGTTTCAGGATGTCTAAGG +AAAAATCGCATTTACATTAAATGTTTAGTAGGCAACCAAGTTTAGACTGTAAACCAAAGA +GTATCCAAGAATGCTGTGGCATTCAAGGCTCATGCTTTTATGTGCATTACAGCACCTTAA +GGCCAATAAAGGGGAACTCCCATCCCCTGTTGATGTGTATTGAAAATAATTGAATGCTCA +AACTCCTAGCCTAAAAAAGAAATATTATCGAATGCTTCGAAAACATAAATTTAGGAAGTG +TATTTTGCCAAGGTTAAGGACACACCCGTGACACAGCCTCAGGAGGTCCTGACGACATGT +GCCCACGGTGGTCGGGGCACAGCTTGCTTTTATACAATTTAGAGAGGATGAGGTATCAAT +ATGCGTAAGAAGTACATTGGTTCAGTCCGGCAAGGCGGGACAACTCAAAGTGGGGCGGGG +GCTTCCAGGTCATAAGTAGATAGAGGCAAATGGTTGCATTTTTTTTTTTTTTTAGTTTCT +GATTGGTCTTTCCAAAGGAGGCAATCAGATATGCATTTATCTCAGTGAGCAGAGGGGGGA +CTGAATAGAATGGGAGGCAGAGGCCCTAAGCAGCTCCGCTCCCAGCTGGACTTTTCCCTG +CTTACTGATATTGGGGTTCCAAGATTTACTTTCTTCACAAGACTCTATTGAGTCCTCAGA +AAACGGTTTTCAAACCATCTTTCTGATTTCCGGTTGCGTAATTTTAATCTTATTCCGTCA +CTGAATCTTGTACATTAGTGGTTTTGCAAACTATGGCCTGAGGTCTCTCTGAATAAGGAT +CATTTTAAAGGATTGTGTTTTTGCAGATGATCTTAGAAGCATTCTTCTTTTTCTTTCTTT +TTTTTTTTTTGAGATGGAGTCTCACTCGATCGCCCAGGCTGAAGTGCAATGGCGCGATCT +CAGCAGCTCACTGCAACCTCCACCGCCCGAGTCCAAGCAATTCTCCTGCCTCAGCCTCCT +GAGTAGGTGGACAGGCATGAGCCACCACACCTGGCTAATTTTTGTATTTTTAGTAAAGAC +CGGGTTTCACCATGTTGGCCAGGCTGTTCTTGAACTCCTGGCTTCAAGTGATCCACCTGC +CTCAGCCTCCCAAAGTTCTGGGATTACAAGTGTGAGCCACCATGCCTGGCTATTAAAAAC +ATTCTTAACAGTTTATTCTGAACCACAGTGAGCACTCCCTCATTCGTAAGGGCAGCCACC +CTCTTTCAGAAGCAAGTGTGTATTCTCCACCCTTCAGCCCCTGGAGGGATTTCCACGGAT +TGTCACAGCCCCTGAAAACAAGCTTCCCAGGGCAAACAGTGGTTTTCCAGAGACTCCAAA +AGGGAAAACAGTCAGGACGCTCCAGTCCCAGCTCCAGCCCAAGTTGTAGCCACACCAATC +TCTGCAAAAACAGAACCATTTCCAGAGTGACAGCACTTAGCACTCTGGTTTCTCTAAAAC +AGCGCCCGTCATGTTCAATTCATATTAATCTCGATGGAATTGTTGCCGTGGATTTTTCTT +GACATAAGTCACTTCTACTTTTACTTTGGATTCATAATTGTCGATGAGGTGGCAACTTAA +ACAATAGATATGTAGCTTCGTGTTTGTCCGTCCGTGAGCCACCTTTCAATCAGAGCCAGT +CAAGCCAAACCTAGGAGAGACTTTCCCGTGGAGGGATTGGGGCTTCTGAGGAAAGCTCAT +GGAGAGAATCGTGATGACAGAATTGAGGATCATCCTGCCTTGATGCCCAAGGAGGTAAGC +AAGGACACAAAAGCACGCTCATTTCACCCCAGTTAGGTGGTGTCTATTATCAAAAAGACA +AAAAATATCCACTGCTGGTGAAGATGTGGAGAAAGGGGAACTCTTTTCCACTGTTGATGG +GGATTAAAAATAAGCACAGCCAGGATGGAGAAGAGTATGAAGGTTCCTCAAAAAACTACA +AATAGAACTACCACATGATCCAGCCATCACCACTGGGCATTTATCCGAAGGAGAGGAAAT +TAGTATATTGAAGGGACATCTGCCCCCCGTCCATGTTTTTGCAGTTTATTCACAACAGGC +AAGATACAGATTCAACCCAAGTGTTTGCCAAAGGATGAATGGGTAAAGAAAATGCCATGT +ATAGATATACCATGGAATACTATTCAACCATAAAAAAGAAGGAAATCCATCATTTGCAGC +AACATGGATGGAAATAGAGGACATTATGGTAGGTGAAATAAGCCAGAAACAGAAAGTTAA +ACACCACATGTTCTCACTCATCTGTGGGAGCTAAAGAAATTTAACCTCACAGAAGTGAAA +AGTAAGGCCAGGCACAGTGGCTCACTCCTGTAATCCCTGCACTTTGGGAGGCTGAGGCAG +GATGATTGCTTGAGATCAGGAGTTTGAGACCAGCCTGAGCAACATAGCAAAACCCTGTCT +CTGCAAAAAAATACAAAAATTAGCTGGGTGTGCGGTACTTGCCGGTGGTCCCAGCTACTC +GCAAGGCTGAGGTGGGAGGATCGCTTGAACCTGGGAGGTCGAGGCTGCGGTGAGCCGAGA +TCACGCTGCTGCACTCCAGCCTGGGCAGCAGAACAAGACCCTGTCTCAGTAGAAGAGAGT +GTACTAGAGACTAGGAAAGGTGGGGGAAGGAGAAGATAGGGAGAGATTTGTTAAAGGATA +CAAAATTACAGCTAGACAAGAGGAATATGTTGTCATGTTCTATAGCCCTGTAGGATGACT +ATAGCCAACAGTAATCTATAGTTTCAAATAGCTGGACGGAGGATATTGTATGTTCCCAAA +AGAAAGAAATGGTACATATTTGACATGAGGGATATGCTAATTACCCTGACCGGATCACTG +AATATTGTAGGTATTGAACCATCCCTGTGTACCCCATGAATATGTACAATTATTATGTGT +CAATTTTTAAAAAGTAAATTTTTTTTTTTTAAAAAAAAGTATGTTCAACAGCCAGCAGCC +ACGAGAAGGTCATCAGCTGGTTTCATCCACAGCAAGAGATTGCTGGCTCCAAATCCCCAC +CCCATCCTCAAGGGGCAATATTGCAGAAAGGAGGAGGGTGGGAAAAAAATCTCAAGAATT +GGAGAATCGCCGGTTTCCAGGGCCCAGAACAAGACCCAGGAGGAGATGAAGATCACCCTT +GCAGGTAGAAGCTGTCCCTGTCTGGGTAGTGCTGGGGACAGTAGGTGGCCCTTCTGCTGT +CTGTCTGAGCATGAGCTCAAGGCCAAGGGTAAGATGAGGGGAAATGACCCCCAGCTGGGC +TGAGCGTACTTTGTTTAGGGTATTTAAGCAGTTCTCAAAAGTGATTGCAGAACCTGTATC +TCCCATCTCAGGGACTCTGCCCAGCCTCACCCCTCCCTCCACCCCACTGTCATGCCCACG +CTTAGGCTTCAAAACATCAATGGAAGATGATAGTGCAGTGCCCAACTGCAGGCCCTTACA +TGAATAAACTGTACATCACAGAGGGGGCGGCAAGGGAGGGGAAAACAGACAGATCCAGCT +CAGATGGAATTTGATCTGAAGGAAAGTGATAAAGTGAAGAAGGGATCTGTCAGCCCTGCA +AGCGGCCCCAGGCACAGCGTGAAGGGGAGGCAGGGAGAGGTCATGCTGGCCTCAGACTTG +GACGCTGAAATGTTTAGTTACAGCCGGAGGGGGGACGCCTGCATAGGTCCTAGGGAAAGG +AGGGGACACCCAGGCATTGGAGACCCACTGTGTAGACGACTGCGAGACATGCTTAAATAT +TTAGCAGAAAGGAAGAGAAATTCGAATAGAGAGATTCAGGAATGGGAGGAAGGGATGGAG +GTGAAATCAAAGCTGTTTAAATACAGATGCTCTTCGATTTACAATTGGTTTACATCCCAA +CAAACCCATCGTAAACTGAAATATCTTAAGTCAAAAATGCATTTAGACCAGGTGCAGTGG +CTCACGTCTGTAATCCCAACACTTTGGGAGGCCAAGTGTTGGCAGATCACTTGAGCTCAG +GAGTTCAAGACCAGCCTGGCCAACACGGTGAAACCCTGTCTCTACTAAAAATACAAAAGT +TAGCCAGGCTTGGTGGCGTGCGCCTGTAATCCCAGCTACTCGGGAGGCCGAAGCAGGAAA +ATGGCTTGAACCTGGGAGGCGGAGGTTGCAGTGAGCTGAGATCACACCACTGCACTCCAG +CCTGGGTGACAGAGCAAAACTCAGTCCCAAAAAAAGAAAAAGAAATAGAAATATAAGCAT +AAACTTAAATAACTGGGGAGCGTTATGTTGGCTGACTGCAACACAGATACGAAAAACCCT +GACAGAATAAAAAGAATTCTAACCAAAAAGGTATTTTGGGCCGGGCACGGTGGCTCACAC +CTGTAATCCTAGCATGTTGGTAGGCTGAGGCAGGCAGTTCACTTGAGCTCAGGAGTTTGA +GACCAGCCTGGCCAACACGGTGAAACCCTGTCTCTGCTAGAAATACAAAAATTAGCCGGA +AATCGCTTGAACCCGGGAGGTGGAGGTTGCAGTGAGCTGAGATCGTGCCAGTGCATTCCA +GCCTGGGCAACAGAGTGAGACTCCGTCTCAAAAAAAAAAAAAAAAAAAAAGGTATTTTGG +AGTTCCTGTGTCCACATAATTTCATCCTTCGATCTCACCCCCTATTCTCCCCACCTCTCC +ATCCTAAGGTCGGTGAATACTGCGTCGGGGAAATTGACCTAAAAAAATTTGTTATGGTCT +ATATATTCTCTGATGAGGGTATTTTTCTAAAAGCAATGAAGTCTTCAGGCTTTTAAAAGG +AAGGGATTGGGGGGCGAGGGGAGGGAGAGCATCAGGACAAATAGCTAATGCATGCGGGGC +TTAAAAGCTAGGTGACGGGTTGATAGGTGCAGCGAACCACCATGGCACACGTATACCCGT +GTAACAAACCTGCACATCCTGCACACGTATCCCAGAATTTAAAGTAAAAGCAAAACAAAA +CAAAACTCTTTTTAACAAAAGGTATGTTGATTGATTGGAGATTATTATATTACGGTCACA +TTTTCCAAGATAATATTTGATAACACTGAACAAGGAGTTGAAAATTTGAGCTGTTTTGTA +TACTAGTTATGTGACTTTGGATAAATCAATAAATATTTCTGAACATCTTAAAAAAAAAAA +AAAGAGGGATGCTGTCCATACGGTATCTGATATATAGCTCACCCTCCGCATCTATGGGTT +CCATATCTGTGGATTCAACCAACCTTGGATCGAAAATATTGGGGAAACAAAATTGCATCT +GCACTCAACATGCACAGACTTTTTTCTCTTGTTATTATTCCCTAAACAATACGACATAGC +AGGTATCAACATAGCATGTGCATTGTAATAGGTATGGTAATTAACCTAGAGATGATTTAA +AGTCTATGGGAGGATGTGCATTGCTTATATGCAAAGACAGTTCCATCTTGTATCAGAGAC +TTGAGCATCCGTGGATTTTGGTATAACCAGGAGGTCCTGGAACCAATCCTCCATGGATAT +CAGGAGAAATTCCATTTCATTAATTCGTACTCCCGGTGGTCTTTGAAATGAGTCGTGCAA +CATCACTGTCACCTGCTGTCCATTTAGTGAGTTACTCTGGGTTTTTTATTTAGGGGAGCT +GAAACACAGATTTTTAAAAAAAGTTTATTTTCATAAATCGCAATAATGTCATAAAAGCTG +AGTGTGCGTCTGGGGCTCTTTAGTCCAGTAGCTACTTTGGTATATATAATGATGGCAAGG +TTGACGTGTTTTGGTTTTGTTGTTGTTGTTGTTTTTGAGACAGGGTCTCGCTCTGTTGCC +CAGGCTGGAGTGCAGTGGCACAATCTCGGCTCACTGCAGCCTTGACCTCCTGGACTCAAG +TGATCCTCCCACCTCCTCCCAGGTAGCTGGGACTACAGGAGGTGCCACCACACCTGGCTG +ATATTTTGTATTTTTTGTAGAGATGGGTTTCACCATGTTTCCCAGGCTACTCTTGAATTC +CTGGGCTCTAGCGATCTGCTCATCTTGGCCTCCCAAAGTGTTGAAATTACAGGCGTGGGC +CACCGTGCCTGCCCCAGATCTGTGTTTTTTAAAGTAAAGCTGAATATTAATTTTTTCCAC +ATACATTAATGTATTAAGGAAAAAGTTGCAATTAGTATCTTCTCCAGCGTTTTGTCTTCT +AGTATTTGGGGTAGGGAAATGTAGTTAATTAAAAGATTACAGATGTCCTTCAGTTTTTTT +TTTTTTAAGCTATCAAGTTTTTTTACTCTTTTTGTAGTGCATCTTATTTTATTCATAATA +CACCTTTTTGTTGAAGTATGTCTTACTTTTTTATTTATTTATTTATTTTTTTGAGACAGA +GACTTGCTCTGTCGTCCAGGCTAGAGTGCACTGGTGCGATCTCGGCTCACTGAAGCCTCC +GCCTCCTGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCCAACTAGCTGGGACTACAGGCA +TCCGCCACTACACCTGGCTAATTTTTTGTATTTATAGTAGAGCCGGGTTTTCAGCATGTT +GGCCAGGCTGGTCTCGAACTCCTGACCTCAGGTGATCCACCTGCCTGAGCCTCCCAAAGT +GCTGGCATTACAGGCATGAGCCACCACGCCCGGCCTCTACTAACATTAGTAGAACCGTTG +ACTGTGTCCCATATATCTATGACACAGTTATCTGCATTTTCTGTCAATCTTTCTCCCCAT +ACTTCAGTCTACTGACCTATTTTCTAGTTAACTGATCTCTTTGGCTATGTCTAATCTGTT +GTTAAACCCACATTCTAGCTTCAGTTATTATGTTTTTAGTTCAAATTAACATCAGATTTT +TAGTTCAAATAACATCAATGTAGTTTCAATACTACCTTGAAAATTTTTATCTTTTTCCCC +ATCTTATTTAAAGTATTTCTCACATTTAATTATAGTCCATGTCTGATAAATTACATATCT +GGGTTTCAGGTGGGTTTGGTTTTGTTGTTTAATTTTGCTTGCTCTTGATTTTCACTCATT +TGGTCTTTTCTTGTTGTATGATAGTTAATTTTTTAATTGACAGCCAGACATGGTAAATGA +AAAAGAATTGCAAAGACAATTTGTAGCTCTGAATCATATTATCATAACCCAAAGAGGATT +TTTTTTTTTAATTCATGTGATTTGATGTGATTTGTCCATACCCTGAGGTAGTTTGCCCAG +ACCCTATCTGGGGCTGAGCTGGAGGGAAATTGGGCTTCAGTGTTTGTGATGACCAGTCTA +TTTCTGGTTCTCCTCTCAGTGAGGTCACAAAAGAAAGCTTGTGGTGTGTACCAGGGTCCC +TCATTGGTCCTGATTATTAATATTTATGGACCCCTCAGCCTCCTAGCACTGCTGGCAACT +CTACTCAGTTTCTCAGCTTCCCAGCCTCTTATTTGCCCTGAGTGGAAGTAAGGTACCAAA +TGTGACATTTACCTCTTCTGTTTGTCTCTGGTATCTTCACTCTTAATTTTGTGCTGCCTT +AGTAGCTCTCTGATGCACTTAAAAAAAAAAAAAATTCTAGGCCAGGTGTGGTGGCTCACA +CGTGTAATGCCAGCACTTTGTGAGGCCAAGGCAGGCAGATCACCTGAGGTCAGGAGTTTG +AGACCAGCCTGGCCAACATGGTGAGACCCCCATCTCTACTAAAAATACAAAAACTAGCTA +GGCATGGTGGCACGTGCCTGTAATCCCAGCTACTCGGGAGGCTGAGACAGGAGAATCACT +TGAACCTGGGAGGGAGATGTTGCAGTGAGCCGAGATGGTGCCACTGCACTCCAGCCTGGG +CAACAGAACGAGACTCCGTCTCAAATAAATAAATAAATAAATAAATAAATAAATAAATAA +ATAAATAAAATTCTATATACATTATTTGTGCAGCCTTTTTAGGTATTTTTGGCAGAAGAC +TTAGTGTGAAACAACAGCTTCACCATTTGCTGAAAGTGGAAAAAATCTCATTTCAGTTCC +TGAGCTGATACATATATATTTGTATTTTTAGCATTCACCACCTCCAGCAGTAATAACTTT +CACAAATTTATAGCCCATAATGCAAAGGAGTGCTTCCTTTTTTGCTGTAAATGTTATCTC +CTTGGATTGTGTACTGGAACATTCTGTGTCTGCTGTCTATCTGTTCCCTGCCTCGTCTGC +CTTTACGATGTCCTCTCTCAGCTTTCATCTTCCCACACAGAGCATTTTGTTTTAAGCATC +TCTGCATATCTCAGCCTCTTTCCAATGACCTGAGAATTCTTCTCTGGCCTGCCTCCAGTT +TCAGAGTCCCTTCTTTCAAGGTGACCCCATCTTCAGTCAGGCTTTTAGGGGATACATCAG +TAGAATAGTTATTACCTAAGGATAAAAAGAAATGCAGTTTGTAAAAGTCACATTTTATAT +TCATGCATTCACAAGCTTGCCAAAAATGTTCTTAAGAGCGGACTTTGAGATTGCTGCATT +CTCATCTTAAAATTTCTCTCTGCATGATATGCAAGGGGGAAGTGTCTACTTTTTACTAGT +AAAAATAATGGCCATATTTATTCATAAAAGTTGGTTTATGTTTCGGCTGTTAATATTACT +TGTTAAGTAAGCCTCTGGGTCTTGATTAGAAACATTAGCAAGGGCTGACTGAACTTCTCT +TCCTCGTTTAAATTCGTAAGATTAACACATCTGCAGAAGGCAAGCTGAGAACTTGCATCA +TTATTTCATCCTCTGTAATCAAACATATAACCCCGAGTTAAATCCCTTCCGAGGAAGGAT +TATACTTCATGATCGGCCCCGTGGAACTTATTTATGTGTTTATCGTTGGGAGAAATTAGA +TGACAGAAACAGATTGACATTTTCCCTAATCCATTTCCAGGAATGGTTTTTTGAGCACTT +ATTCTTTGCCTGTCTGGCTGCTTCATTTATCCATCACAATAAGTGTCTGTGTGACATCTC +ACTGAAAGCCCCATGACTCAGAGAGTCATTTCTGCAGGTCCTTTTCCTTGATGGGTCAGT +ATTCAAATCCAGGACATCCCTCTACCAGCCCTGGTTGAAGAAGGAAATTATTCATTTTTA +TGGGATTCATATGGTTTATGATAATGCAGTTATTGCATTCGTCATTTTTTCCCAAGACTC +ATTTTGGTGTTTTGCAAGGCGCATACCCAAATCCCGCTCTCTCACTTGCTAGTTCTCGTA +TGTTGGGCAGTATCTCTGTCTGCAGATTAAACTTTGCAGCAGTAAGAGGGAAGGCTCAAC +CTGTCTGCCTCATAGGGCTGTCGCGATTAAAAGGAATCAGGGCTGAGAAGTTTATGAGTG +TCACTCAGCAGCCAGCCATGAGCAGCCACTAAAAAAGGAGTCCTGTTATCATGGTTGTCT +GATATCTTTGACAACTTATAATTTTGTGTTACACCATAATTCTTAGAACTTAATTTTATA +TTTGGATTTTACATACATAGCTGAGATCTGAAAGAAGAAGCCCATATTTTATTTAATGTT +AATTTTTAAAAATTTCTCTCCAGCTGTATTGAGGTACCACTGACAAATAAAAATTGGTGT +GTATTTAAGGAGTACAATTTGATGCTTTGCTGTATGTATACATTGTGAAACAATCATTGT +ATCAAGGTAATTAACATTTTCATCACCTCGCATAAATGCTGTTTTCTCCTCCTCCTCCTC +CTCTTCCTCCTCTTTCTCCTCCTCCTCCTCCTGCTGCTGTTCTTGGTAATGAGAACACAT +AAGATCTACTCTCATAGCAAATTTTAAGTACACAATCCTATATTGTTAACTGTGGTCACC +ATGCTGTATGTTAGATCCCCAGAACTTATTTATCTTGTGTAACTAAAACTTCATATTCAT +TCCTTCACCAACATGTCTTCATTCTAAGCACCCCGCCCCCAGCCCCTGGCAACTACTGTT +CCACTCTATTCTTCTGTGAGTTATTTAAAGTGCACTTTCGGAGGCTGGGCATGGTGACTC +ACCTGTAATTCCAGTACTTTGGGAGGCTGAGGCAGGCAGATCACTTGAGGTCAGGAGTTC +AAGACCAGCCTGGCCAAGATGGTGAAACCCCATCTCTACGAAAAAATACACAAAAAAAAT +TAGCTGGGTTTGGTGATGCATGCCTGTAATCCCAGCTACTCAAGAGGCTGAGATAGGAGA +ATCACTTGAACCCAGGAGGCAGAAGGTTCAGTGAGCCAAGATCATGCCACTGCACTCCAG +CCTGGGTGACTCTGTCTCAAAAATAAAATAAAATAAATAAATAAATAAAATCAATTGCAC +TTTCGTGATTATGAGTTAGAATAGTCAAATTAAAAAAAAGGTTCATGATTACAGTGTTCT +CTTTTACATCTTAAAGTTTCAGTAAATCTCACTAATAATGACTTTTGGGGGTGTTCAGTT +TTTATAGATACCTTTTTTCTATTTCTTTCTGTGCTCCTGTTCCTCTGCCTTAGGGCATTG +CACATGCTGATCTGCTTTCACGTGCATTTTTCAGCATGTTCTTCTTCTTACTTCATTTCC +AGTCGTTCTACATCATTGGCTTCTACTCAGCCTTCAGGCTTCATTTTAGATATTACTTCC +CTAGGAGTGTCTCCCCCTTTAGACCAGGTGAGGTCTCTTGATAACATTTTCTTTCCTAGA +ATTGATAACCATTTTCTTTCCTAGAATTGATAACCATTTTCTTTCCTAGAATTTCTCATG +GCTTGCCATTTTGTATTTGTTATTTGTTGATTTTCTGTCTTCTTTGACAGTAAGCTTCAT +GAAGGTGCAGATCATATCTGTGTAGGCCACTGTTTAATCTTCACTACCTACCTCTCCATA +AACACCTGTGAAATGCATACATTCATGCCTCGATTAGGAGAATGAACTGGACATTCTCCT +AAAAGGGAATGCTAGGATCAGAAATTTGGGAGCTGAGTATCCGAGTGACTGATCTCCACC +CCAGCTGACATCACTCAAAATCTCTGGGATCATGGCCTGCGGGTCTGCATTTGAAGGATT +ACAATTCTCTGAAGTTGGCCTGGTGCAGGCAAGAGGGGCTCATGTTGAGGCTCAACCCCA +TCCACCCCCAAGAATTCCACAGTGTGTTTTCAGTGAGGATGTCAGTGTTCTCTTATCTCT +GTTGCTCACACTCATTAAGCTAACTGCTTTGTGACCTGACCTGATGGGGGCCCCAGTGTT +TGGACACAGGTTTGCTTCTTGACCCTGTATTTGTCAAGGTAGGCTAGCTGCTATAACAAA +CAGCCCCCAAATAAGTAAAAGTTTATTTCTCATTTGTATCACAGCCAGCTGGGGTGGCCA +AGGTATCCTCTACCCCATGCAGCCTTTCAGGGATCCAGGATGCTCCTATTGTTGTGCACC +ACCTTCTAGGGCAGCTCTTCTCAAGTGAGACTCCTTGGGAGGATTAGGCGCTGTTGCTGA +CGGCAGCCACTGTACGTAATGCATTAAGTAATCTCCTCCCCATCTAGCATGGTGTTAGAT +ATGGACCATCCTTGGGAGAGTTGAGAAAAGAGTCACCTGATTTGTTCTCTGTTTGGTTTT +ATTTTCTTATGGAGGCCCAGTTCAGAGAGGGTGGAGGGATCTTGTTTTTCACCTGGCTGG +TGGTAGAAGAGAGGATAGGAATATCTTATTCCTCTCGTTGCCCAGCCCAGAGGTGACTCA +CATCACCTCCTCACATTCACTCACATCACCTCCTCACATTCACTCAATCTGCTTGTGGGA +ATCACTTCCATGGTCCTGTCCAGGTGCAAGGAGGTCACAAAATGCACTTAGACATTAGCC +CGAGAAGAAGAAGAAACAAACACAGGTATTGGTGAGCATATCACCTTGCCCCAGTCCTAT +CCCATATCAAGTTGTATTTGCACCATAGAGGCAGAAAAAAATGGAGTGGGTATTTTCAAT +TAAGTTGCATTTATTTGCACGAAGGTTTGACTTAACTTGCCTTTGCTCTTTCTTTATAAC +AGATGATAGCTTGTCCTGAAACTGAGACTCCTGCCGTGATAACGTGTGACCCACTGTCCC +AGCCTTCCCCTCAGCCTGCAGACTTCACAGAGACTGAAACCATCTTGGTATTCCTCATCT +ATATGACCTACACATGGCCAGCTCTCTTATTGCTTGTTATTTTCTCACAGGGTCTATCCC +CATTACATACCAGTGGGGGCGCCATAGGCTTTTAAAAATTCCTCCCTTTTTTTTTTTTTT +TTTTTTTTTTTTTTGAGTGGTTTCTCCCACCTGGAATAAGTTGTGTTATAATTAGTCTAT +TTCTCTATTATCCAGGTGGATAAGGAATCTGGCTGTCTGTTCGAACTTATTGTGGGGTTT +TCTTTTTCGTCATTTTGTTATTCTCTTCCACTTTGCTTAAAAAAATTAATAAGAAAAAGA +TACAGCGTCTATATAGCATCTATGTCTCCATTAATTTTTTTAAACTTTTGATAGGACTTG +CACCATGTCTAAAATCAATATTCCATGACTATGGATTTTATTTTAATTCTTTTTTTCTCT +AAGTTTACCCTTATGAATCTGGGCTTTTATTGCCACATATCATCAGAAAACTGGCTTTAT +GGACACCCCCCTGTTTTTAAACTCTCAAAGAGACTATCTTAGTAAAATGCTTCTGTAGGC +ATTTGGTATAAACAAGTCAAATCTCTCTCTGAAAATTTAACTTCCATGAATTGCATAAGA +ACTTGTAGCATCTCCTCTTGTCTGAGACTTGGTGGATGGCTCAGAAAAAGTGAGGGGAGA +GAAGCTGAGCTATTTTTAGCATTCCCAGAAAAGAAGATCGAGTACAGTCCATCAGTTTTT +TTAAAAAAGTTAATTATAGTGCCGGCCGCGGTGGCTCACGCCTGTAATCCCAGCACTTTG +GGAGGCCGAGGCGGGCGGATCATGAGGTCAGGAGATCGAGACCATCCTGGCTAACACGGT +GAAACCCCCGTCTCTACTAAAAATACAAAAAATTAGCTGGGCGTGGTGGTGGGCGCCTGT +AGTCCCAGCTACTCCGGAGGCTGAGGCAGGAGAATGGCGTGAACCCGGGAGGTGGAGCTT +GCAGTGAGCCGAGATCACGTCACTGCACTCCAGCCTGGGCGACAGAGTGAGACTCCGTCT +CAAAAAAAAAGTTATAATAAAGATGAGGTCTTGCTATTTTGCCGAGGCTGGTCTCGAACT +CCTGGGCTCAGGCAATCCTCCTGCCTTGGCCTCCTAAAATGCTGGGATTACAGGCATGAG +CCACCGCGCCTGGCCTCAACCCAATAATTTGATTTTATTTTACCCCAGGATAAAGAGTTC +TCCATCATTTAGGTTAGGGCTACAGTTCCCTGCAGCCCACCGCAGACTAATGATGGAATG +GTTATGTTTTAGCAGCCAGCAAATAAAGTCGAAAGTGTCTCATCCGAGGAAACCTTCGAA +CCAAGCCAGGAACTCCCTGCTGAGGCTCTCAGGGACCCCAGTCTGCAGGATGCACTGGAG +GTGGTATCCAAATTCTTCCCCTTGCCCAAGGCTCCCGGTGGGGGCCATCCACCGTCACTG +AGGTCAACTGCATGCACACAACAGCTGTTAATTTTTCAGCCTCATTTAACAAAAAATAAG +AATCGGCTTCCCTCTTCCCCTGCCTCTGATTCTTCTGTCTTCTCTCTGGCATTTGCCTGG +GGTGATCGGCCGACTCTCTTTTGCCATCTTCAAGTCTGATCATCACGCTTTTTCTCTCTT +TAAAAGCTGTTCTGCAGAAGGGATCAGGAGGGAAGTTGAGGGACTGTGGAAATTAATGCG +TAGCAATCCATTTTCTGAAATGAAGAGATTAAAAGCTGAAAATTGGAGGGAGTGGGGCAT +GCTAATGTTCGAATCCAAATGGGGCATGCAAATAATTTCTTCTTTCAGGATGAAATGAGA +GATGCATGCTTTCTGTTCCTTCCTCTTAGAGATGTTTTCATCTTCAACTACGTTCTCTCC +ATTGATGCATTTAATGAAAGCAATTGCTAACGTTTTCTCTTGCTCTTTAAGCATGATCTA +ATAATGCCATTTGGTCTTTAAGTAACAATCAATACAGCTCTAGAGCTAGGTTTAGGTCTA +GACTGAAAGTTGGTATTGAACGCATGTTTAGAGTGTGACCTACTGTGTTGGCTAAATGCC +TTCCCTGGACAGTCACCCTTGGAGAAAATGTGAACTTGTTTTTCTCATTCTTACTTGGTT +ACTGTTCAAATGCAGCATTTTGAACTTAATTTCTAGAGCTGTTGGTTGAGGTCCAGGTTT +CTTATAAACATGTGAATGTATCCCTTCAGCATGTTCCATCCTTGTGGTCATCATTTGAGG +CTCTGTGAATTGAATCTGTAGTTATTAGTGAGTGACAGGGCATCAGTGTGAGGTTGGGTA +AGACCTACGTTGGACAGCTCAGCCATGTGGTAGGTTTGGGATCCTGGATGAGTTCATTAC +TTTTTCTTTTTAAAAATTATTATTATTATTATTATTATTTAGGGACAGGGTCTTGCTGTG +TAGCCCAGGCTGGAGTGCAGTGGCATGATCATAGCTAAGCAGTCTTCCTGCCTCAGCCTT +CCAAGGAAATGGAACTACAGGCATGGGCCACTGCAACCAGCTAATTTTTTATTTTTATTT +TTTGTGGAGTTGGGGTTTCACTATGCTGTCCAGGCTGGTCTCGAACACCTGGCCTCAAGT +GATCCTCCTTTTTTGGCCTCTCGAAATGCTGGGATTACAGGCATGAGCCACCGCGCCCAG +CCTGAGTTCATTACTTTGCTTCAGTGTTCATGAGGTGGAGACTGGGTTGCCCACCTCACA +GAATTGGAAGGAGGGGTATTAAAAAGGAGAGTGGTATAGGGAAAGCCCTAGTTAGTGCTT +GGCTCATAAAGATGAGGAAGATTTCGGTCATTGATTTGCTAAACCGGGGCACTTTGACCT +CCTGTGTGTCCACACTGTCCTCTAGGGGAACTTTATTTAGTATCTTGTATAATACCCTAA +TTCATAACATTGGAGCAGCTTGTTGTTTTCTTGGATACTCATCTCTTGTTAGCAGAAATG +TCACAATCACTGTGCTGTTTTGTCTTGAAAACTAGTATAAGGTTGGGTGCTGTAGGTCCT +GTTAATTCCAGAAACATTTCATTCTCAGGAACTGAATGGATCTAAATGCAAGTGCTCTTA +GAGGGGAGAAATGCTGCAGTATCCTGAAGTGGACTTTTTAATTTATTTGTTAACTCTTGC +TATCACCTTAATCAATAGGATGGCTGTCTTTAAATAAAATATAATATATGGGAATGAGTG +TAGAAGGCAGAATCTTATATGTAAAAACCTTCTAAAAACACTGCGGCAAGTAATTAGAGA +AGAAAGTAGTATATGCCTATGGTGTAAAAACTCAAATTTATCTTTCTATATATCTATCTC +TATACATATCATGTATCTATCTATCTACCTCTTATCTATTTTCTTTTTTTTTTTTTTTTT +GATGGAGTCTCACTCTGTCACCCAGTCTGGAGTGCAGTGGCGTGATCTCGGCTCACTGCA +ACCTCCGCCTCCCGGGTTCAAGTGATTCTCCTGACTCAGCCTCCCGGGTAGCTGGGACTA +CAGTCACCCACGACCAAGCCCGGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCACC +ATGTTGGCCGGGCTGGTCTCGAACTCCCGACCTCAAGTGATCCACCTGCCTCGGCCTCCC +AAAGTGGGATTACAGGCATAAACCACCACACCCGGCTATCTATCTATTTTCTATCATCTA +TCTCATCTATATATCCATTCATCCTCACATCTAGATAATAGATACATAGATATAGAAGAG +ATAAAACATAGGTAGTAGATAGAGATGATAGATAAATGAATGATAGAGTGATAGATGATA +GATAGGTAGATAGGTAGAGAGATATTTTAGATAAATAGATAAATGATAGAGTATAGAACG +GATGGATGGATGGATGGATAAATGGATAGATAGATTGATAGAAAGTAGATAGGTAGGTAG +AGATCATAGATAGATAAATAGGTAGATAGATGATGGAGTGATAGATGACAGATGATTTAT +TGATAAATAGAATGGATGGACAGATGGATGGATGGATGGATGGATGAGTGGATAGATAGA +ACATAGGTAGATAGATGAGATAGATGATAGATAATAGATGGTTGGTAGATGAGATAGATG +ATAAATAGATGATAGATAGATAGATAGAAAGATGTGTGTGTGTCTATTATTGTTACCATC +TTTAAATTTTTAAGAGTCTTTTTCTAGTTCTTGGTAAGAAGTGTTTAAAGCAAATGTATT +TGTTCTTTTTGTTGACTCATCTGAATGCCAAACAAAATGTGTGTGTGTGTGTGTGTGTGT +GTGTTGTTACACACTTGCATTTTCATCTGTTTTTTCACATGACCCTTAAGAAGGCAGGAA +CTCTGCCATTGAAAAAACTATCTGAATTATTATTTAAATTCCTTTGCCAAGCAGTCCAAA +TTCTTATAGGCTTTACTTACAGGAGGTGAGTTGTTTTTTCATTTAACGTAGTTTGGTTAT +TCACTGTCATACAAAACAGAAGTTTTGGTGGGTGAGAGTATTAAATTAGTGTGTGTGTGT +GTGTGTGTGTGTGCACATGCGCATGTGTGCATGTGTGTGTTTAAAATGGTTTAGTGGCTA +GAAATGAAAACAATTCTTCAGAAAAAGAGAACATATACAATTACATTTTATAAAATTTCA +AAACACTTAAGCAAAAAAAATTATCTTCTAAGCATATTATACTAAATCTAGTGTATATTT +AGCTCAAAAGAAAAGTGCTGCTGGGTGTGGAGGCTCACACCTGCAATCCCAGCTCACTGG +GAGGCCAAGGCAAGAGGATTGCTTGAGCCCGGGAATTCAAGACCACACTGGGCAACATAA +TGAGACCCCATCTGTGCAAAAAATACAAAAATCAGCTGGGCATGGTGATGTGCCCTGTAG +TCCCAGCTACTGAGGAGGCAGATGTGGGAGGATCTCTTGAGCCCAGGAGGTCAAGGCTGC +AGTGAGCTGTGACTGCACCACTGCACTCCAGCCTGGACGACAGAGACCCTGTCTCATTAA +AAACAAAGTGCTAGTGATTCGCAATCTCTTTTTGAGAACTGAGATGCATCTTTCTGCGGG +ACCCTACACTGGATGGGTTTTAGCAGTCTTTCCCTCGATAATGGACAGCTGCAAAAACCA +TCTCCCACTGACTGTCTTCCCTAGGTCGACCTGGCCGTCTCTGTTTCCCAGATCTCCATC +GAAGAGAAGGTGAAGGAATTGAGCCCCGAGGAAGAGAGGAGGAAGTGGGAGGAAGGCCGT +ATCGACTACATGGGGAAGGACGCGTTTGCTCGCATCCAGGAGAAGCTGGACCGGTTCCTG +CAGTAATCCGGCAGCTGGTGGGCGTTGTGTGTAGTTAGACAATGTCCTGTTGGGTGGTCC +TGTTGCGTGGAGATCTCCTCTGGTCCTTTCAAAGGGAAACGCTGTTGAACCTTGTGCCTC +TATTTATGCTTAATCCATTTGAGTGCCTCACACAAAAAACGTAGAGTATAGAAATCCACC +TTAAAGCCCCTCGCCCCAACTTCTCCACCAACGCCTTCTGGGCTTTCTTCAGAGGTCACT +TCTACCCTTGAAGCTGTCGGCAAAAGCGAGCAGTAATAACATTCTAGTAGACTCTCGATG +GTGGTCTCCGCTCTTGCCCGAAGGACCTCTGAAGTACGCTGGAGCTGTGTTGTACAGGTG +CTGTGAGACCTACCCTATTCAGAATTAAACCTCACTGCAAATTTCCTCCCATCACGAAGC +TAACAACACTAATATACGTATTTAGCACCTCTGAGGCTTTGCCATGGAGACCCATTTCTG +TAGGGCTAAGGAAACATTTAGACGTGGTGACTGACTTTCATTTGGACTTGGCGAAGTGTA +TCTGAGAAACACCTCGGCTGTGGTCTCTCTGCTTTAAATCCTAACAGGACTTCCTAGAGC +GTTGACAGAAATTCTACTCGTGGACGTTGGGAAGAAAGATTGTAGGTGGCTTGGGGAATG +TGGGTGGCTTAGAGGATCTAAACCGATTCACTTCCTGGTTGAGAAGCAACGAGGGCTTGC +TCTAAATCGTTTAGAGGATAACAGGATCTAGAGATGCTCTCTGCTTGACAACAAAAGTCA +GGGTGCAGTCGGTCCACCCTTGACTGCTCTTGGCTTGGTCTCTACCCTCACTACCTCAGT +TCTCAATAACTTAGTGAATCACTGCCCTCCTCAAAGCCATTTCCACTCAGCTCTTTCCAG +AGAATTCTCAGTTTTATGAGACGGGAAACTTTATTTCACGAGAAAGCCTCATTGTCAGAA +GTATCTTCATTCAATGGGCACAATATGCTGTGTATCTCACCAGGTAGCTGTCAGGGGCCA +CCGAGAGTGTCGTTAAAAATGGGCATGGTTGTAATAAAGGAGGAAAGTGCGACTTTTGAA +ATGTTTGGAAGGTTTATTTCTCATGCACATTCCAGGGAAAAGCAGAGAGTAAATTAGAGA +CGGGATAGGAAGGCCGTGGGAGAACTCGATCCTAGCCTGTGTCAGCTGGATGTGTTTACG +TGGAGAGGCGTGGCCACTTTTTAGGTCACCTGAAGCAGTTTAGCCTTTGGATAGAGGAAC +CTGCCTGAATTTATGGCATTAGTGGTGGCATTTTTTTGTGTACAAGATGTGGGTGATGGA +GGGGCTGTTTCTTTTTCCGTGTGGGTGGTTAATAATCGTCAGTCTCGGAGGGCGAGGCTC +GTAGGATATTTCAGGTGAGTCAGGGTTGGATGGTCATCGGCTTTCAGAAGGAGACCACGG +GAATGTTCAGGGAAACAATGTCAGCTTCTCTGAGGACCAGAATTCATGTTCACGGGCAGT +GATGAGTTGGCTTATGGAGTGAGTCCAGTCTGGAATTCCGCCGTGCATTCTAGCCTGTAT +CATCTCATTTGGACAAATGCTGGCACGTTGAAATTAAAATGTTAAAAAACAGCCATGTGG +CCTCCTTCCAG diff --git a/test/csq/ENST00000381157/ENST00000381157.fa.fai b/test/csq/ENST00000381157/ENST00000381157.fa.fai new file mode 100644 index 0000000..75d9abc --- /dev/null +++ b/test/csq/ENST00000381157/ENST00000381157.fa.fai @@ -0,0 +1 @@ +X 54071 21 60 61 diff --git a/test/csq/ENST00000381157/ENST00000381157.gff b/test/csq/ENST00000381157/ENST00000381157.gff new file mode 100644 index 0000000..5cb519a --- /dev/null +++ b/test/csq/ENST00000381157/ENST00000381157.gff @@ -0,0 +1,14 @@ +X ensembl_havana gene 21 54051 . + . ID=gene:ENSG00000056998;Name=GYG2;biotype=protein_coding;description=glycogenin 2 [Source:HGNC Symbol%3BAcc:4700];gene_id=ENSG00000056998;logic_name=ensembl_havana_gene;version=14 +X ensembl_havana transcript 26354 52324 . + . ID=transcript:ENST00000381157;Parent=gene:ENSG00000056998;Name=GYG2-010;biotype=protein_coding;havana_transcript=OTTHUMT00000377085;havana_version=1;transcript_id=ENST00000381157;version=2 +X havana exon 26354 26388 . + . Parent=transcript:ENST00000381157;Name=ENSE00002101522;constitutive=0;ensembl_end_phase=1;ensembl_phase=2;exon_id=ENSE00002101522;rank=1;version=1 +X havana CDS 26354 26388 . + 1 ID=CDS:ENSP00000370549;Parent=transcript:ENST00000381157;protein_id=ENSP00000370549 +X havana exon 27731 27857 . + . Parent=transcript:ENST00000381157;Name=ENSE00003500720;constitutive=0;ensembl_end_phase=2;ensembl_phase=1;exon_id=ENSE00003500720;rank=2;version=1 +X havana CDS 27731 27857 . + 2 ID=CDS:ENSP00000370549;Parent=transcript:ENST00000381157;protein_id=ENSP00000370549 +X havana exon 31076 31298 . + . Parent=transcript:ENST00000381157;Name=ENSE00003569036;constitutive=0;ensembl_end_phase=0;ensembl_phase=2;exon_id=ENSE00003569036;rank=3;version=1 +X havana CDS 31076 31298 . + 1 ID=CDS:ENSP00000370549;Parent=transcript:ENST00000381157;protein_id=ENSP00000370549 +X havana exon 32755 32955 . + . Parent=transcript:ENST00000381157;Name=ENSE00003507737;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003507737;rank=4;version=1 +X havana CDS 32755 32955 . + 0 ID=CDS:ENSP00000370549;Parent=transcript:ENST00000381157;protein_id=ENSP00000370549 +X havana exon 47043 47147 . + . Parent=transcript:ENST00000381157;Name=ENSE00003507910;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003507910;rank=5;version=1 +X havana CDS 47043 47147 . + 0 ID=CDS:ENSP00000370549;Parent=transcript:ENST00000381157;protein_id=ENSP00000370549 +X havana exon 52285 52324 . + . Parent=transcript:ENST00000381157;Name=ENSE00002095888;constitutive=0;ensembl_end_phase=-1;ensembl_phase=0;exon_id=ENSE00002095888;rank=6;version=1 +X havana CDS 52285 52324 . + 0 ID=CDS:ENSP00000370549;Parent=transcript:ENST00000381157;protein_id=ENSP00000370549 diff --git a/test/csq/ENST00000381157/haploid-diploid.txt b/test/csq/ENST00000381157/haploid-diploid.txt new file mode 100644 index 0000000..29c04f1 --- /dev/null +++ b/test/csq/ENST00000381157/haploid-diploid.txt @@ -0,0 +1,9 @@ +31140 A T missense|GYG2|ENST00000381157|protein_coding|+|76N>76Y|31140A>T . + +31177 C T missense|GYG2|ENST00000381157|protein_coding|+|88A>88V|31177C>T+31178G>T . +31177 C T missense|GYG2|ENST00000381157|protein_coding|+|88A>88V|31177C>T . + +31178 G T @31177 . +31178 G T . synonymous|GYG2|ENST00000381157|protein_coding|+|88A|31178G>T + + diff --git a/test/csq/ENST00000381157/haploid-diploid.vcf b/test/csq/ENST00000381157/haploid-diploid.vcf new file mode 100644 index 0000000..cc46b49 --- /dev/null +++ b/test/csq/ENST00000381157/haploid-diploid.vcf @@ -0,0 +1,11 @@ +##fileformat=VCFv4.2 +##contig= +##FORMAT= +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT SAMPLE1 SAMPLE2 +X 31140 . A T . . type=ENST00000381157:2777948-A-T GT 0|0 1 +X 31177 . C T . . type=ENST00000381157:2777985-C-T GT 1|0 1 +X 31178 . G T . . type=ENST00000381157:2777986-G-T GT 1 0|1 +X 31180 . C T . . type=ENST00000381157:2777988-C-T GT . 0|1|1 diff --git a/test/csq/ENST00000382647/ENST00000382647.fa b/test/csq/ENST00000382647/ENST00000382647.fa new file mode 100644 index 0000000..990b3b6 --- /dev/null +++ b/test/csq/ENST00000382647/ENST00000382647.fa @@ -0,0 +1,52 @@ +>5 5:1798480-1801500 +GAGAATGAATGAACTAAGCTATTCGGAAGGTCTATTTTAATAGGAAAATGTTTTTTAGTT +GGAACGTTTTGGAAATAAGATAACGCAATGTCTTCTATAGTTACTCATTTACACTGAAAC +GTGATGGGTAACTTTTAGGGCGTTTGCTTCCAGTCACTTTCCCCTGACTCCTTGATGTGA +TAATTCCTTCCATAAGATACAACCATTCTCCCAAGTGATGCGATGACGAGTATGTGCGTG +ACTCTGGAGGGAAAGGGTCTACATCTGTCTCTGCTTGTGCCTCGGATGGGTTTTACAGTA +GACGTACCACCGACCCCGCCTCTTCACCAGGTAACAGTCCTTGCAGCGCTTCTTAAGGAC +AGTCTTGTTTTTGAACCCCAGCGCAGGCAGCAGATGGGGCAGGAGGCCGGGTGAGAGAAG +TGAGCGCACTGCTGCCCCGGGTTCCACAGCCACGGGGGCTGCACCTCGAATGGATCCAAA +TAGAAATGTGGAGAGGGCTCGAGGCTTCACCGTGTGACGACTGAGATAGAGCAGAGGGTT +CACCATTTTCCTTATAAAAAGATTTGCCATGTTGTGGTGAATCTATGGGAGAGAGAAAAA +AAGGAGTTATAGCTTCTCCTGCACTTCCACCTGCTCTTTAAGGCTTCCTTTTCTCTGTTT +CACTGAGGCTTGGGAAGGCAGGGACCTCGGGGACTGAGGGTGTTCCCATACCAGCTGCAG +CCTCGACCTGAGCTTGAACACTGCCTTAATCAGCCAAGTGTGCCAGGAGAATAAGGGGCA +GTGGACGGTGGCTTCCTTCCCTTTCCCGCCTGCTGCAAGTGTAGGTGAGTGTGCAAAGCC +CTGCGATGTTGAGGAGCCGCTCACTTGGCTGGGAGGGAGCTTAAACTTAGGCCGCATCCC +TTTCCAAACAGACACCAGGTCAAGGACGGTTCAACTGATGAGCTCCTCCCTCCAACTCTT +CCCAGACCCAGGGGCCCTCCCTCGGGCCAGTTTCGGGACAGGCCCCCGCTCCGGAAGAGC +ACGGAACTCTGGCACCCCGGTCGCCCGCCCCTGCTTCCCCACGCGCCCCGGCCCTTAGGG +TTCAGCGGCCCCGGCTGGGAAGAGCTGGGCCTGCAGGGCCCGGAGGACACTGCGGCACCG +GAGCCGGCCCTGCGCGCGGGCTGTGAGGTCGCGTTCGGGAGCCGCCAGTTCTCCCGCCCC +GGGGTCGCTGGACACCCCCTCCTGTCGCCAGGTCGGGCGCCCACGGTCGGACCCGCACCC +CCCAACCCTGGCCCTCTGAGACCGCCAGGCCCCGGCCCACGCTCCTCTGACCGCAGCCCA +CTCGGGGAGACACGCCCGAGGGTCCCAAGGTGGCCGGCCCCACCCTCTCGCAGCCCCCAC +TCTCAAGACACCCGGGACCCCTGACCTGAGAAGACGGCTCCCTTACCCGGCCGCACGCTC +TCACCCGGCGCCGACCCCTGCGTCTGCGCACTGGCACGCGGACGCTGCTGCCAGGAAGGA +AGATGGCGGCGGGGGGGGGGGTCACGTGGCGTGCCCACGTCCAGTGCGGGGCGCAGAGAC +GCAGCAGCGAGTGCGCAGGCGCTGGAGTGCGACGTATCACTCCCCGACTGCGCGCACTCT +GCGGGCCACCGGGATCGTCGTGCTGTTTGGAGCGCTCTCGGGAAAAAAAATGCAAAAACC +AGGAACGAAAATGGATATCCGCAACGAAAAAGAAATTACAACCACTTAGGCCTTAGAAAA +AACTGGCAAATACCAATGTCAAAACAAACTGAGAAAGAGGACATGTTTTTAAGTGGACAG +GAGAAATGTAAACAGGCTCCGGGAAACGAGTGGAGACGGGCAGTAGTTTCAACTGGTTAC +GGCTGTTTTCCCCAACATTATGAAAAACTTCGGACATAGAGAAAAAGGGAAAGAACTGTA +CGGTGAACACCCATATACTTGCCACCTAGATTCTACCCTTAGCTCGCTTATCCCTGCCTT +TTCAGGTATCTACCCGTAACTCCATTCGCCTTCCTTTTTGTGTGTGTCCGGGTGAGTTGC +AGACGTGGCTGCGTCCACTCCGCGCTCCCTGCAGGCCCCAACGCTTCATCGCAGCGCCCA +CTTTTTCCACCTGACCCGGCGAACACCGGGCGGGCCGCTGGAGTTTATCAGCTCCAGGAC +AAATCTGCCTCTGACCACCACGTTTGCTGGGACATCTTTGGGACCGGAGGTTTTCATGTG +CATTCTTGTTTCTCATGCCTTTCCTCCTCTTTATCATCTTCCCCGCCACTCATCCATCTC +TAGTGTTTTGTTCTTGGAGTCACGTGGTCCTCAGGCTCTGACCACAGCAAAAGAAAAGCT +GGATGCTGGAGCTTAAGCTGGGATTTATACCCAAGTCAACTCTAAGCAAAACGGGCCTTT +TTAGAGGCTGTATTTGCATGCTGTAAAATCAGTCGGTGTACTAGGCTTTGTTGCAGAAAT +CCCCAATATACGTTTCCTCTGCGGCTCCCCGTAACCACACACAGGAACGCTTGCCTTGAA +CGAGGAGAATGCACTTCCAGTCTCGTCTGCTAAGCAGTTGACTCCTTCACCCAATAATTT +TGATATTTAAATGTCTCATGATTATCGGTTACCATAAGAATATAAACAATGTATTTTCAG +TTTACATCCTCCCCTGCCTGTCCGCTAAATAAGAACCACTGGGTACTCCTAATCGCTGAA +GGTTTCGCACACCATTGCCTGCCTCATCAGGGCCCTAGCTCTAGCCTGCGGCTGCAACTG +CATGAGGCTGCACCTGCCGGCGCAACGGGGCCGCTTAACTTTTAGGCCATTGATGAAAAG +TCAAACAAGCGCACAGTACTCGGTGTAATCAGGGGCATTTTTAGCGAGATACCTGGGATG +AAAACGGGTGACCACCTGAATCAGAGAGCAGCTCCGGCGCACCCTCTGCCCCGACCCGCG +CTCCCCGCCCCCAGGGCGAAATAAATACCGGGTGTTTGGCGCCGCCAGAAGCCGTGCGCA +TGCGTTAGCGCTAAGCGGGAC diff --git a/test/csq/ENST00000382647/ENST00000382647.fa.fai b/test/csq/ENST00000382647/ENST00000382647.fa.fai new file mode 100644 index 0000000..f91bb3d --- /dev/null +++ b/test/csq/ENST00000382647/ENST00000382647.fa.fai @@ -0,0 +1 @@ +5 3021 21 60 61 diff --git a/test/csq/ENST00000382647/ENST00000382647.gff b/test/csq/ENST00000382647/ENST00000382647.gff new file mode 100644 index 0000000..993803b --- /dev/null +++ b/test/csq/ENST00000382647/ENST00000382647.gff @@ -0,0 +1,8 @@ +5 ensembl_havana gene 21 3001 . - . ID=gene:ENSG00000171421;Name=MRPL36;biotype=protein_coding;description=mitochondrial ribosomal protein L36 [Source:HGNC Symbol%3BAcc:14490];gene_id=ENSG00000171421;logic_name=ensembl_havana_gene;version=8 +5 ensembl_havana transcript 25 1473 . - . ID=transcript:ENST00000382647;Parent=gene:ENSG00000171421;Name=MRPL36-003;biotype=protein_coding;ccdsid=CCDS3865.1;havana_transcript=OTTHUMT00000365909;havana_version=2;tag=basic;transcript_id=ENST00000382647;version=7 +5 havana three_prime_UTR 25 258 . - . Parent=transcript:ENST00000382647 +5 havana exon 25 582 . - . Parent=transcript:ENST00000382647;Name=ENSE00003238927;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003238927;rank=2;version=1 +5 havana CDS 259 570 . - 0 ID=CDS:ENSP00000372093;Parent=transcript:ENST00000382647;protein_id=ENSP00000372093 +5 havana five_prime_UTR 571 582 . - . Parent=transcript:ENST00000382647 +5 havana exon 1445 1473 . - . Parent=transcript:ENST00000382647;Name=ENSE00001492895;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001492895;rank=1;version=5 +5 havana five_prime_UTR 1445 1473 . - . Parent=transcript:ENST00000382647 diff --git a/test/csq/ENST00000382647/synon-splice-region-insert.txt b/test/csq/ENST00000382647/synon-splice-region-insert.txt new file mode 100644 index 0000000..4d451cc --- /dev/null +++ b/test/csq/ENST00000382647/synon-splice-region-insert.txt @@ -0,0 +1,3 @@ +1443 A ACCCGGCCGCACGCTCTCA splice_donor|MRPL36|ENST00000382647|protein_coding +1443 A ACCCGGCCGCACGCTCTCA splice_donor|MRPL36|ENST00000382647|protein_coding + diff --git a/test/csq/ENST00000382647/synon-splice-region-insert.vcf b/test/csq/ENST00000382647/synon-splice-region-insert.vcf new file mode 100644 index 0000000..16a3bb0 --- /dev/null +++ b/test/csq/ENST00000382647/synon-splice-region-insert.vcf @@ -0,0 +1,7 @@ +##fileformat=VCFv4.2 +##contig= +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO +5 1443 . A ACCCGGCCGCACGCTCTCA . . EXP=splice_donor|MRPL36|ENST00000382647|protein_coding;type=ENST00000382647:1799922-A-ACCCGGCCGCACGCTCTCA, should be synonymous splice region if seq were checked: ...GCTCTCAc|ccggcg diff --git a/test/csq/ENST00000390520/ENST00000390520.fa b/test/csq/ENST00000390520/ENST00000390520.fa new file mode 100644 index 0000000..5d3a107 --- /dev/null +++ b/test/csq/ENST00000390520/ENST00000390520.fa @@ -0,0 +1,3 @@ +>14 14:22995792-22995894 +CTGGGCCTTAAATCATTGTGTGATCAAAGCTGCAGGCAACAAGCTAACTTTTGGAGGAGG +AACCAGGGTGCTAGTTAAACCAAGTGAGTACTGGGGCTTGACC diff --git a/test/csq/ENST00000390520/ENST00000390520.fa.fai b/test/csq/ENST00000390520/ENST00000390520.fa.fai new file mode 100644 index 0000000..5c33683 --- /dev/null +++ b/test/csq/ENST00000390520/ENST00000390520.fa.fai @@ -0,0 +1 @@ +14 103 25 60 61 diff --git a/test/csq/ENST00000390520/ENST00000390520.gff b/test/csq/ENST00000390520/ENST00000390520.gff new file mode 100644 index 0000000..5e4192b --- /dev/null +++ b/test/csq/ENST00000390520/ENST00000390520.gff @@ -0,0 +1,4 @@ +14 havana J_gene_segment 21 83 . + . ID=gene:ENSG00000211872;Name=TRAJ17;biotype=TR_J_gene;description=T cell receptor alpha joining 17 [Source:HGNC Symbol%3BAcc:12045];gene_id=ENSG00000211872;logic_name=havana_ig_gene;version=1 +14 havana J_gene_segment 21 83 . + . ID=transcript:ENST00000390520;Parent=gene:ENSG00000211872;Name=TRAJ17-001;biotype=TR_J_gene;havana_transcript=OTTHUMT00000410981;havana_version=1;tag=basic;transcript_id=ENST00000390520;version=1 +14 havana exon 21 83 . + . Parent=transcript:ENST00000390520;Name=ENSE00001508149;constitutive=1;ensembl_end_phase=-1;ensembl_phase=1;exon_id=ENSE00001508149;rank=1;version=1 +14 havana CDS 21 83 . + 2 ID=CDS:ENSP00000451250;Parent=transcript:ENST00000390520;protein_id=ENSP00000451250 diff --git a/test/csq/ENST00000390520/deletion-overlap.txt b/test/csq/ENST00000390520/deletion-overlap.txt new file mode 100644 index 0000000..afb9725 --- /dev/null +++ b/test/csq/ENST00000390520/deletion-overlap.txt @@ -0,0 +1,3 @@ +81 CAAGT C coding_sequence|TRAJ17|ENST00000390520|TR_J +81 CAAGT C coding_sequence|TRAJ17|ENST00000390520|TR_J + diff --git a/test/csq/ENST00000390520/deletion-overlap.vcf b/test/csq/ENST00000390520/deletion-overlap.vcf new file mode 100644 index 0000000..9f00059 --- /dev/null +++ b/test/csq/ENST00000390520/deletion-overlap.vcf @@ -0,0 +1,7 @@ +##fileformat=VCFv4.2 +##contig= +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO +14 81 . CAAGT C . . EXP=coding_sequence|TRAJ17|ENST00000390520|TR_J;type=ENST00000390520:22995872-CAAGT-C diff --git a/test/csq/ENST00000409523/ENST00000409523.fa b/test/csq/ENST00000409523/ENST00000409523.fa new file mode 100644 index 0000000..04160e3 --- /dev/null +++ b/test/csq/ENST00000409523/ENST00000409523.fa @@ -0,0 +1,1079 @@ +>2 2:120059781-120124424 +TAAGAATCAATATTCCACAATAATTTTTAATAACAATTTATTTCCCTTTAAAAAGATCAA +ATGTTTTTCTCATAATATATTATTTTACAACAACAAAGAAAAAGAAAGAGAGAAGGAAAG +ACCTGAAGAGAAAGAAATAACCAGATTTTAGCTCAAAGAGTATAGCCTGGGATTAATTTT +TTAAGATTTGTTTGTCAATTTCAAAAATTCAGCAGTGGAATAAAGAGCTTAATACAGGTA +TGCAAAAAGGAAGCCCTCGAGATGTTTTCACCAGGATGAAATGGGATTAGCTTTGTAGTT +CTTATAATCTTCTTCACAGAAGAATGCAATTTCAGTTTCACTGGCTGAAAAAAAACAGAA +AATGGAAAAAAAGATTTTAATGTAAATCTAAATTTTAAACAAGTATGGAAATCCATATGA +CTTTGATTCGGTATTTCAGAATAGCTTCAGATGCCCAAAGTGAAAAAGATGAGTTATTTG +TTGGGTCGCACAATGCATTTTACCAAATCAACAAGAAGTTTCAGGTGAAGTTTTAAGAAT +CAAAACCTCAAATGATTTAAAAGTAAAAAAGAACAAAAAATAAAAAACCAAAAATTAAAA +TCAAGAGTTAATACAAGAATCTGGTTTTCAGGAAATCATAAAATTGCTCATTTACAGTCT +TTTTTACAGTGCTAGGAAATAAAAAACCTTGATTTTTTTCTCAAATATGCTACTCAGGTA +CTGAAGGAAGGGGAGGGAAAACTCTTTTCCCCCCCTGAAATTAGCCTGTAGGTATAATAA +TTTAATACTTAGAGGATCAGTAGAATATTTTACAGATCACTTTACATTCTCCCTCATGAC +CCATCAAAATATGTGTCTGAAGAAGTTAATTTTTTGCCCTGCTTATGATTAATTCATGCG +GCTTCAACAATATGCAAAGTGAAAGACACAAATTGGCTTCTACCTCAATACCTTCAAATA +CCTCTAATTATTCACAAGGGAGATGGCACAGCTAAAGGACCCATGAAGGTTCAGAGCAGT +CACAATTCTTTCAACCTAGCAGGTCAAGGACTGCGTCTTCTATAACAATAAGTCAGCAAC +ATTATTAATTCAGGCTAGAGACAAATCTGATGGAAAGCCTTCCAGTTATTAAACATGCAA +TTCTTTAAGGTGTTGTGCCAACAAGTTCCACATTCATTTTTCAAATTAAACCAGAAGTTA +ATACAGTCTGCTTGGCTTTTACAGAAAGAGCAAAAGGGCCTTCAGAATCTCCACAAGAAA +ACAGACAAGATTATTCGTAATGCATACTGAGCACTCAATTAACATACTCTCTAAAAACAG +ACAAGTAAAACTCTCCAAGTCAAATAAATAGCATAATAAGAAAGGGTGCCAAGGATTACC +ACTCGTCTCTTAGTTTACAACTCTCATCTCATCATTAGACTTTATCACAAAATAATGAAA +TTAATGAGATTAGCATGCCATTTCATTAAAAATGTTTTTGCTGTTTTCAAGAATATCCAA +TTTAATGTTTGTTAATCATAAGCTACCCATGCTCATTACAGAAAATAAACAAGTGTCAAA +AGAAGAAAATAAAGCCACCCATAGTCACAGATCCTCATTCCAGTCCTCTACTATATCTTC +AAGATTAAATTTAATCTGAGTAGATGAAAATCAGACTGCAACCTCGCATGACAAGGAGCC +TGTGGGGGATACAGCACAGAGAAACTGGAGATCAATAAGGAGGAGCTGTAAAAAGATGCA +CCCTGTGCAAACAGTAAGTTAAGGTACAGTTAAATTTTACAAGAAAGTGGCATCTAAAAG +AATGGGTAAAAGACTCCTCCACACTTGGAATCAGTGGGAAAAAGAAAATCAAGAAAGAGA +GCTTCAAAAACTTCAATATTCAAAGATATTTGGAAATCTATCCCTTATAGAAAAAGCTCC +TGGGGTTTCCTTTTTTGAAGCAAAGCATGCCCAGAGGTAGATGTATATAATTTGCAAGTG +ATTCTAATCAACCTTCTAATGAAGAATGAGCAAAAGACACCCTGTTCTTAATAATCACAG +AGCAAGGTTTTATCTGTGATGTGCTATTTACATACAGAACTTTACACAGTGCTTTGCCCA +CACAGCACTTCGCTCAGTCCACGCTAACTGTAATTACAATTTTCACTTACTGCAGTTGAC +ATTTATCTGAACCCCTTTTGAGAAACTAATATGTTGTGTGGCTCTTCAGCAATAGTAGGT +TCAGAGAAGCTGCTGGAAAGCAAGGAGTTCTGTTTTGACACATAGGTTCTTTTGGATCCA +GTTAACTGAAACATCAATCCATTATTTACATAAGGCATTTATGCTAGCTCTCAAAATGAG +AGTCTGCAGTGTAAAGATTTTATTTTCAGATGACTGCACTTGTTTTCAGGAAATCTAGGT +AAACAAATGGGTTAAACTATAATACTTCAGGCTGATTTAAAAAATTTTTCACCCTTAACA +AATTGGAAAACACACAAATTAAAATTTACTCCAAACATTCAAAAGTAAAACATTAAATGG +GTTTTAAATTTTAGTAATGTGGTCCTTAAGAAGAAGTAGAATATAATGTTTTCTTACATC +TGTAAGACTCTGTGGAAAATGTTTCAGAGAATGATTTCAGGGACTTATGCTGCAAATTTA +TTTGCCAATTTATGTGAAAACCAATTATAAATGATTTTTAAGGTTTCTACATCATCACTT +TCCACCATTATCCCTTAAATTCCTGCTTCCCAAATACTATTTAAAATGGCTCCTTTAAAA +CTGGCTGGGGATGAACCCTCAGGAAGTCTACCTTGTGCTGGTCCCCCAGGGCACCTGATT +TTAAATTAAATGTGCTGCAGGCGGCAGTGCAGTCAGGTGCAGAGTGCCTTGGCATGGGAA +TCTGAAATGAATGTGCAATCTAAAATCCAATAAATACACTGCCACTTCATCCCTTCGTCT +TACTATCAAATGAAACCAAGAACCCTCCAAATACATTTGCAGGATCCTTTTAATACTGAT +GTTCAAGTTTAATGAAATAAACACAAGCTAGGGCTTTCAAACTTTGGATATAAAATTAAT +CATTTTATAATGCTTCCAGACAGACAGACAAGACACACACACACACACAACTTTAACAGG +AACATAATGATAATGACTTTAAATGAAAGAATATAAGAACAATCGATTTTAAGTATAAAA +TCCCAAGAAAAATTAAATGCAATGTATTTAAACTCTTAAACTAATTTATCTCAATAAACT +CATCTATCAACAAGGATTTACCCATATGTCTGAGTCCCTAGCCTCATGCTAGTCAGCACC +AACGTAGTATGAGGCACAGCCCCTGTTGTCTGGAAAAAGGAGCCTGAGACACACGCACTG +ATTTTGTGGTACAGAAAATCCACAATCTTGGAAGCTGACATGTGACAATAACTGCACACT +GTTGACAAAAAAAAATACAGGAAGGGCGAGGTGTGGCTTCTGTGGCAATCTGAGACCAAA +AGGACAAAGTTTCACCCTCTCTCCCGCTCTAGGAGTATAGCCTAGCCTCCCAAATGTCAT +AAAATCCTAATCTATAAATCATTCAAAGCTGTGCTCACAGCTGAGTTATATTTCTAAGTT +TTCATCACCAACAGACGTCCCAAGTGCTGTGCCTTTTATTTCATGACTTGCTTCAAATAT +TTGTTTTGGATCTGCTGGCAGAGAAGATTTCAAACTACAGTTTGAAGAAAACAACTAGCC +AAAAAAAAAAACAACAACAAAAAAAAAAAAAAACAAAAAAAACCTCGGTCTTTGATAGAC +TGGGTACATGCCTGTAATTTCCACCATGGTGTGGGAAGGTAAAACGGGAAACACTCTACA +GAGGTTCACTCTGAGTCCTGCTTCTGGAATCCCCCAGTTTCCTGGGTCCGACACCCACAT +TACCGAGTAACCAGATTATCACTGTTTCTATGTAAGAGTGAAGAACGGCCACCATAACAT +ACTGTCGAAGGAAGAAAACACGCATGACCTAAAATATTGCTACCCAGAAAAAGAAAGGGA +ATGGGACTCACACCTTAAGGAAACACAAATCAAACATCATCCCGAAAGAGAAGGGGGAGC +CACAGAATCCCACAATATTAGCTGTACAGACAAGATCACCCAAAGGGGCGAGGCGTGAAC +GACAGGGTTCCAGTTGGGGGCAGATGACAGAAGTGACACGCAAAATGAAAACGAACCACG +AGGGAGTTCTGGAATTATTACAGGACCTGGCTTGCCGAGAATGCTTCCCTCAGATAAACA +CTTAGAGTTTGGCCGCTGTATCTTGTTTTAAAATGTTTCCAATGAAACACAACTGGCTTT +GGAAGAGTTACCCAGCCACAATTTCTCTCTTAAACCAGACCAGATTCGAAAGACAACAGT +AGTAGAATGTAGCAAAATGAAAGAGAGAAAATAACACTTAAAAAAAAAAGCTTACATGTA +AATTTATTACTTAGGGGAATTAGCCCATAAAACTACAATTGCTGACAAAAAATTATAAGT +AACATTTCTAGGTAAAAGTCTCTTCTTGCTTCTACTGATCAAATCTTTTTGAAGTACGTA +TTTTCGTACTGGGTCCACAAGCAAAAACTCCACTGACGTCAGGTGTAGAATGTTCCACGG +GGATCTGCAGTGCAGATAAAAAGCCAAAGGATGAACTAGAGAATTTCTCCCTGAGAAAAG +AAATCTTCAAACACCTTTTTTTCCCCTAATTTCCCCACTTGCAGCCTTTCTTTTCCTTTC +ATGACTACTGCAGAAAAGTCCTAACGATAAATTTGTTACCCTGGCATTATTCCCATGGCA +ACTGGCTGTGATAGCAGTGACAGCTCTACAGCAAGATCAAGCAGTGAAAAGGGAGACAGA +GATGACTTCGAATTTTTCTCTTAAACCTCTTAAAAATCTAACCAGACACGGCACTGAGGG +AGGGAAAATTCCCTAGAAAAATCACATATTTCAGGCCAGGCACAATGACTCACGCCTATA +ATCCCAGCACTTTGGGAGGCTGAGGTGGGCAGATCACTTGAAGTCAGGAGTTCAAGACCA +GCCTGGCCAACGTGGTGAAACCCCGTCTCTACTAAAAATACAAAAATTAGCTGGGCGTGG +TGGCACATGCCTGTAATCCCAGCTACTCAGAGGCTGAGGCAGGAGAATCACTTGAACCTG +GGAGGCGGAGGTTGCAGTGAGCCGAGATCGTGCCACTGCACTCTAGCCTGGGCGACAGAG +AGAGACTCTGTCTTAAAAAAAAAAAAAAAAATCACATTTCAAGTATCATTTTCACAACTC +AATTCTCACTAGAATTTTTTGTTGCTCTCCAGGTACCCTCATCTCCTTCCCCAGGTATAA +CCTCAGCTTGTCCCCAAGAGCATAGCAACACCACTCTAGATAACAAAGAGAAAATCGCTC +CCTGCAGGGACCCAAATCACCCCGAGCCCAGGGTTGCTGGCTTGCCGGAGTTCGGAGTTA +GGAGTTCGGAGGGCAGTTTGGAGTCCTCACAACACCCTGAAATGAGTGGAGAATCTGGGA +AAATAATCTGACTCTGATCCAGGACCAATAGCCTTAAAGTAAGAGGACAAAAAGAGGGAT +TTGCTTCTCACCTTTACAGATGGTTCATTACATAAGTCAGTTTGAAATTAATCACAACAA +GACCAACAACTCAATATTTTAGTAAAGTCAAAACTTGCCAACTGCCTTCTCCAGGACAGT +TTCCAAACAAAGCAGTTGTTCCTGAGGGCCTTTTACACACATCACTCCGGATGCCTTCAT +TGTTTTACACAACCTTTATGACAACCTTCTAGAATAGGTTTCATTATTCTGTTTTTACAG +AAAACAAAATAGAGTTTCAGAGAGGATAAGAGGCTTACAGAAAGCAAGCAAAGCACACAG +CCTTCATTCTAACCGATTTTCCCCAACTTCATGGGTTTATACTTTTAAAAAAAATTCGTC +CTTTAATTACAAGGAATACATGTAAACTGTAGAAAAATTTTTAAATCACCATAAAAGCAA +TTAGATAATACAGAAAAGAAAGAAGAATATCAATTACTGGCAATGCCAGCACCTCAAGAA +ACCATTTCTATAATTTTGGCGTATGATCTTTTCTCCATATACGCATAAACAATAATCTTA +CATGTATACTTTAAACATTTTAAAACAATAATGGGGTCGGGCACAGTGGCTCATGCCTGT +AATCCCAGCACTTTGGGAGGCCAAGGCAGGTGGAAAACCGAGGTCAGGAGTTCGAGACCA +GCCTGGCCAATATGGCAAAACCCGGTCTCTACTAAAAAATACAAAAATTAGCTGGGCATG +GTGGTGCACACCCATAATCCCAGCTACTCAGGAGGCTGAGGCAGGAGACTTGCTTAAACC +CAGGAGGTGGAGGCTGCAGTGAGCTGAGATTGTGCCACTGCACTCCAGCCTGGGCGACAG +AGCAAGACTCTGGTCTCAAAACAAAAACAAAAACAAAAAAACCCAAACAATAATGGTATC +ACACAGTATGTTCTATTTCTATTCAATAAATCAAGCTCTACATCAGTGCTTCACATACAG +GGAAGGTCAGGGCTAACCCCACCACCCTTCTGAAGACTTAGCACAACCTCACAGCTTGTC +CCTGTTGGCTTAGAAACAAGTACCATTGAAATTCAAACTTGAGAAAGTCTTATTGGTCAA +ACCGACCCACAGAAAATTCAAGGTCATATTCATTCCCGACGGTGGTATAAGAGTATCCAT +TTTCCTACACCTTGAACTCCCTTGGACAATGCCACTTTTTCATGTCTGCTAATCTTATAA +CAATTGCTGCTGTCCAAGGTCACCCAGACAGTAAAAGACAGAATCAGGTTTTGGACCCAA +GCACTCTGGCTCTGGACTCTGTTATTTTCATAGAGATGAGCATGCTAATTGTTGTGCAGG +CTAATCTAGAGCTCCTGGCCTCAGGCGATCCACTAGCCTGGCATCCCAAACTGCTAGGAT +TACAAGCATGAGCCACTGCACCTGGCCCCAGACTAGAGTCTTAACACTAGACTCTACTAC +ATAAAACAGTATCTATGTACTCATTTCTAATAAGTACTCATTCTCTCCTAATAAGGTGGA +GCTATTTTTTATGTGTGAGTTATTTCTTCTATCAATAGAATTTTTCTTTTTCATAGTAAT +TACAAGGGCTCTTTATAAAGTCAGGCTAGTAACTTTTCTTTTTTTCTCTTTTTCTTTTTT +TTTTTTTTTTTTTTTTTTTTGAGATAGAGTCTCACTCTGTTGCCCAGGCTGGAGTGCTGT +GCTGGAGTGCAGTGGTATGATCTCAGCTCACTGCACCCTCTACCTTCCAGGTTCAAGCCG +TTCTCGTGCCTTAGCCTCCCAAGTAGCTGGGATTACAGGCGTGTGCCACCACACCTGGCT +AATTTTTGTATTTTTAGTGAAGATGGGATTTCACCATATTGGCCAAGCTGGTCTCGAATT +CCTGACCTCAAGTGATCCTCCCCGCCTTAGCCTCCCAAAGTGCTGGGATTATAGGCATGA +GCCACCATGCCCGACCCCAGGCTAATAACTTTTTATCTGTTGTATATGCTGCAGATATTT +TTCAAAGTTTATTGTTTCTCCTTTAACTGTGTTTACAGTTTTTAGTTTATAGGTAGTCAA +ATTTATCACTTCTCCCCCTTTATGGCTTCTGTCTTTGAGCTCATGCTTGGAAAACTCTTC +TCCTTCCCAAGATTATGAAATTATTGAACTACACTTTCTTTTTAAAAAATTTTTTTACAT +TATAACATTTAACCCATCTACAATTTATTTTGTAATAAAAACAGAGATGAGATACGAGTT +TGAATTTTATTTTCCTGAATGCTTTGGCAATGGGCTTGACATAATTTTCTGGCTAAATCA +TTCTTTCCTCACTTATTTGAAATGTCAACTTTATCATCCTGTGAAATATTACCCTTTTTT +TCATTTTTGGATTCTCCAGTGTTTTCCATGGAGCTGTCTGTCAACACCCCCATTAATATC +AGTCTGTAATATTCATTATGCTTTATGCTTTAACAACAAGCAGGGCTACCTTATGGGTGC +TACATGCCCCAATCACAAAGGTGCCACCTGCTACAATAATATAATAGCATTTAAAGAAAC +AAATGCCAAATTTAAAATCATTCTTCAAAATAACAACCTTACATATTCATAACATGGAAA +GACAAGAATATTCTAGCAAATATTGTAGACATCAACACAGAAATCAAGTCTAAGATTTCA +CAACATGGTATTTAAGATCCTATTTAACTCAGAAGATCTATGTCAGGAATTCATGCTCAT +CACGTGAATCAATCAGAAGTAAATTCCTGATACAAGTGATTAAAGTAACTCAAAATAATA +CTTGTCAAAAAAAAAATTCAGGCTCCCAATGTGCACCTCACTAACCGTGTTCCTTAACAA +GTGCATATAAATAATTATGAACAATGTGAGGCCGAGGCAGGCAGATCGCCTGAGGTTAGA +AATTCGAGACCAGTCTGGCCAATATAGTGAAACCCTGTCTCTACTAAAAAAATACAAAAA +TTAGCCAAGCGTGCTGGTGCACACCTGTGGTCCCACCTACTCAGGAAGCTGAGGCAGGAG +AATCGCTTGAACCCGGGAGATGGAGGTTGCAGTGAGCCGAGACTGCACCACTGCACTACA +GCCTGGGCGACAGAGTGAGACTCTGTCTCAAAAAATAAATAAATTAATAAATAATTAAGA +AGAAGCATGGCTTGTGACACTGCATCCGTCACCAACCGCAGAGGTGTGTGAGGGGCACAC +TGCCTTTAACCACTCAGACCTCCCTGACAATCTCCACTCCCTCTCCTGCCAGATCAGCTT +TAGGTGTACATATACGTAGAATAACAGTGACATCTAATGGTCACAAAACATGTCACATAA +CATTTATTTAGAATAAAACCACATGCACATTCTAGGCTGGAAGGCCCAATCAGGTACTTT +TCAGCTGCACACACCAGGTTCCTATTTTAAATTCCATGCCTTGGTGGGCCCTGAGTGATT +CGGAAGACTATCAAAAACCACACTGCATGTGATACCAACAATGCGTTTCATTATTCCTCA +TTAGTTCTTACTATGTCCATTTCTCTCCAACCATCGGCTCAAGTGACAATGATAAGAGTA +AGTAGACGTGGTACTTACAACCCGTCACTTAAAATGACCCTCAGGAGAATTCTGAGCATA +CCTTCTGAAAACAGCCATTTGCATTCTGCATATTTGGAGAGCAGACACCTACTGTCCTCA +GCCAAGAGATCGGAATGCACATCATTCTCATCCTCCTCCTCTGAACAGTTACCGGGCAGT +GTCAGGGGGACCAAGGACAGCATTTACTTTCCAGTGAGTTATCCAAATACCATCAGCCAG +GCCTCAGGATAGGCCGGCAGAGGTCCCCCTCCAGCAACACAAGGCCCCCTTCCTCACCGA +TTCCAGCTGCTTTCAGAGTGCTGTCTTCTTTCAGCAGGAGTCTTTCGTCATCTTCCAAAC +TCAACACAAGTTCATTTGTCTAAAAAAAAAAAAGAAAATCTGCATTTTATCAGTACTTAC +ATGGGTTTGTTTGGTGAGACTTCTCAAAGACACAGAGTTGTAACTCTGAGCACAGCAATA +ATCTAAGTAGATTCCACTGCCCTGGCCGTAATGAGGGCAGTGAACAGAGGCACAGTGAGG +TCCTGCCGAGCTCACGCACCACATAAAGCAGTGGGGACAGTTCTGTGGCATGGGCGTGAA +GTCAGATCAGGATGCAAATCCAGACTCCACCAGCACCCAGCTGTGTGTTCTCAACAAGCT +ACACAACCTCTCTAGGACTCGATTTCCTCATTGGTAGAAAAGGGGAGGAGAGGCCCCTTC +CTCATCACCTGTGGTAAGGGTGACAGGATGGGGCATATAAACCCTCAGCAGTGCCGGCCG +CAGGGTGAGCACTCTCTCTTAGCTGTCACTGTTCTTTTGCTGCATCATCATCATCATCTT +CTGCCATCCTCACCTGGTCAGCGACAGAGCTGAGCTTCCAGCTCTGGCCAGTCCGACTTC +TGAGAGAAGCAAGTATACTTCCTTTTTTCGTTTTGTTTTTCGAGACAGGGTCTCACTCTG +TCACCTAGGCTGGAGTGCAGTGGCGTGATTATGGCTCACTACAACCTCAGTCTCCAAGGC +TCAAGCAATCCTCCCATCTCCAGCCTCCTGAGTAGCTGGGACTGCATACATGTGCCGCCA +AGCCTGGCTAATTTTTTTTATTTTTAGTAGAGACGGGGTCTCACTATCTTGCCCAGGCTC +GTCTCAAACTCCTGAGGTCAAGTGATCCTCTGACCTTGGCCTCCCAAAATACTGGTATTA +CAGGCATGAGCCACCACACCTGGCCACAAGTATACTTCAAACGGCCAGAAGTCCACATAT +CTAAAAACCTTGCCCAAGCTAAAAAACATCTGGTTCCATGTCACATTAATTGGAATATTT +CTCTATGTGATTTGGGGTGGGGGTAAATGAGAGTGCTCTCCAGTGATATTTACAAATCCA +GTGAGACTCATAAATACAAGTGAAAATTTAAACTTGCTATTGACTGGGTGCGGTGGCTCA +TGCCTGTAATCCCAGCACTTTGGCAGGCCGAGGCAGGCAGATCACAAGGTCAGGAGATCG +AGACCATCCTGGCTAACATGGTAAAACCCCGTCTCTATTAAAAATACAAAAAAATTAGCC +GGGAGCGGTGGCAGGTGCCTGTAGTCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATGGC +ATGAACCTGGGAGGCAGAGCTTACAGTGAGCTGATATTGCACTACTGCGCTCCAGCCTGG +GCGACAGAGCAAGACTCCATTCAAAAAAAAAAAAAAAAAAGTTGCTATCTGCCCCTAAAT +AGCACAAAGAGATAACCACTAGTGGCACACAGCACTACTTGTCAACCAGAACACACCTGT +TTAGCAACATATTCTATTTGTAGAATACAGCTGAGACAGAGAGTCAACAGAAAGGCCTCT +CAGCAGCCAAATCAGAAGCCCAAGCCACGCAGGGTTTATGGACCTCATTCACTGCAGAGC +ACAGGGGCTTAAAACTCCAGAGCATACAGATTAAAAGAAAAAATACTTTACTCAAAAAAT +CATTTTAGAATAGGTAATACAGTCTGTAATCCCAGCACTTTGGGAGGCCAAGGCAAGAGG +ACTGTTTGAGCCCAGGAGTTTGAGACCAGCCTGAGCAAGATAGCAAGACCCGATCTCTAC +AAAAAAAAAAAGTTTTATTTAATTAGCTGGGTGTGGTGGCACACATCTATACTACTAGAT +ACTCAGGAGGCTGAAGCAGGAGGATATCTTGATCCTGGGAGGTAGAGGTTGCAGTGAGCT +GTGTTCATGCCACTGCACTCCAGCCTGAGCAACAGAGTGAGATTGTGTCTCAAAAAAACA +AAAAACAAAGAATAAGTAATATCTACTCATTATACAAAGTTCTCCAAGCATATATGAATA +GAAAGTGAAAAGTCAGTCTCCTTCCAATCCCCATCCACCAGCTATCTAGTTCTCCAGAGA +GGACTGGGACCACTGAGAGGACCTGTTTCCCACACCCTCCCAACACAGTATATTAGCAAA +GCCTTCTGATCCTTGCCAATCTGACAGGTGTGGATTAAGTATAGTCTTAATTTGTATTTT +ATTATGCTTAAAGTTCTGAATATTTTCTATTTTTTAATGGAATTGTAGGCTAATTTTTCC +AATAGAATTGTAGAGTCTAGAGCATCTTCACATGCTAAGGAAATTCGGCCTTTTCTGTAA +GTTAGAAAAATTTCCCCCACTTTTCATTTGTTCCTTGCTTTTCTCAGTGGTTTTTTTTTT +TTTTTTTTTTTTTACATAGAAGGTGTTAAATGAATTTTCGTGGAATAAATAAGTTAGTGA +ATGAAGTAAAATGTATCAATCTCATATCGTTTCTCAGTTTTCTGTCATATTTAGAAAGCC +CTTCTTCACGCCAAGATTTTTTAAATTCCCTGTTCTCTTCAAATATTTTTAAGAATTTCA +TTTTTTGAATTTTTCATCGTGGAGAATTTCAAATATACAATAGATACAGAATAGTGTAAT +AAACCCCCTGCCCTGTACCCAGGACCCAACTTGAACAAATTATCAAGTCATGTTCCATCT +GTTTCATCTCTATCCTCATCTATGGGTTTAATTTTTTAATCCAAGGGGTATTTATTTTGG +CATAAAGAAAAATACATGGATTCAACTTAGCTGTTTTTTAGATGTTTATGCAGTTATTCA +AATACTATTTATTGAGTCCTCCATCTTTTCTTTACAAACTTGAAATGCCATATTTACTAT +ACATTCAATTTCCATATTTGGAAATATTGGGGTCTATTTTGGAACTTTTAATTCTGTGCC +CTTAAACTACCAGTTCATGTGACAGTGCCATACTGTTCTAATTACTATCGTTTTATAACA +TGTCTTATATGTTAGAGCTAATTACTCTCATTTCTCTTTTTCAAAATTCTCCTGATTATT +CTTATTTTTTACATACTGATTTTAAAATCAGCTTATTTAGTTTACATATAAACACAAGTA +TTGTATTTTATTGGGGCAGCATTAAATATGTAAATTAAGAGAGAACTGATTTTACGCTGT +TGTATCTTCCTATCCAAAATATCCTAAGCATTTCTATTTAAGTCTTATTTTGGAACTCTC +ATAGCAGGTTTTGTTTTGTTGTTAAGTTGAAGTACAGTTTCACACAATGAAACGCACAGA +TCTTGAGAGGAGTTCACTTTAATGGGTCTGAAAAATTAATCGCAGAGTTTAGATGCGTAT +TTTCAAGTGTGTGTGTGGTGAGGGGTGAGGAAGGACAGCAGCATTTTAAGTTTTCTTTTT +AAAGACCTTGCACATTTCTTATAAAGTTTGTTCCAGGATATGACTTCCACACATAAAATG +GAAATTAAAGTTTTTATTTCAATCTTAATAGAAATTATTCCGACTTTATAAACACACCAC +TGATTACCATCCATAATACACACACACATACACACACACACACACAGAGGAGGCTCGGGT +GGGAAGGTATCCAGTCAGTCTTTTTATTGTGGGAATGGGAAGAAATTTCTGAGGATATGT +AGTAACTGCAATTAGGAAAGTCTCTAAGCCCAGAAAATTAGGGAAATGGGGAAAATGCCT +TTTATGAATGAGTTCATTAAGACAAAGGAATTATTTAGAAGTCTCTCCTTTCAGCTGACG +AAGGAGATTAAAATTACAGCTGAGTTGGAACACTAACAGGCCAAGCCAGCAATGCCACAG +GCCCCGCAGATGGGGAATAGAAAATGAAAGGACAACAATAACTTGGAAATGAGAAAAATG +ACTGTGAACTGGATAAGGCACAAATGAGGACATGTGGATGAAGTTTCTCTGAAGTTTTAA +AACCGTATCTGTGAAAATATATTGAACTCTTCCCTTAGAAAAGTTGAAGCAGAAACTTGC +AGAACCATCCCCAGGGCATCTTAACTAGCATTGTTATGATTTGGATCAAAGTTCATAAAG +CCAGATTCCAGAAGCACTCTGAGTGACTTAATTGTTTTGGGAGTCCTCCCTTAAACAAAT +ACATTGTTCAACTGGAAAAACAAGCCCTAATTTTATAACTAGAACCTGCCAGTGTGAAAC +ATATGTCTTAAATATAAGTAACAATTCTAAGATTGTTTTGTCTTCCGATGACAGGATAAT +TTCCAGATTTTTTAAATGTTATAATACTGATAATTTGAACATGATGAACTATGTCTCCAC +TAAGATAAAGGAATAATTTACTACTTACTCCTTTTTGGCAACATGAGCATATGAAAAGCC +AAATGATGTAGAACATGCAGCAATGAATGGAGAATGGGGACTTGCTTTGCTTTACAACCT +TTTTGAAGAGCGTATTGTTTTATTTTAACTTTATTTTATATTTGTATTTGTATTTTAGAT +GTATATAATACACAAAAATATAGAACATTACCTATTCTCTACATTTTAGGAATGAGGTTG +AAAACATTCCTGTCCCAGAGGAGAGAAATTGGACGAAGTCCAAATATGGTGGCCACACAT +TCTAGTACCAATCAAAAGGGCAGATTCCATACCACAGCCCCAGACACGTGTGAGCATGAC +ATTTTGAGGCATTTCACAATGGATATTGTAAAACTGGCATATACAATCCTTGGTATAAAA +AATAAAGTTACTAGAAGGAACCAAGCCTACTAAACCCTTGACTTTTGCTCAGTGAAACTG +ATTTTGGACTTCTGACCTCCAGAATTGTAGGAGAATAAATGTGTGTTGTTTTAAGCCACA +AAAATATTTTTTAAATAACATAAATTTTAAAACACAGTTACTAATCAATGGTCAACAGAC +ATAGCCTCATGCCATTTTCTTGTGATCTGTGATACGCATTTATCTGAAAGGTGATTGAGT +GTATGGAGTGCATCTACGACTACAGAAGACAATGAAATAAAATGAATTAATAAATACTTC +ATTCAAAAATTGTTATGGAAAAACTCCTATGAGCCAGGCACTGTGCTAGGTATTGGGATA +TGACAAATAATATCTTATTCTTGAGTAGTTTATATAATACAGGAAGATTACTGCTTTAAT +GAGGACTCTATGGAAGGCCAGAGATTAAAGAAAAAAAGATCACTCTGCTCTGTCTGTATG +ATAAACAAATCTTTGACTGTGGCTTCATAAAAACGTTACTCTAAAAAAGTAAAAAAACAG +AAATATAAACACACAACAAACCCATAAATAAACAGCTCTCTTTGGGAAAGGTAAGACAAC +TTCAGGATTGCAGGCCATGGCCTTGGTGGAGCTAAAAGGTGTGTTCCCAGAGCCACAGTT +CTGTGCCTTCTCTTATACACAGCAAGAATCAAATTAGAACAAGTGAATTATTTGTGTCTG +CATCTGGCCCTTTTGTTCTGGTACAGAATTAAGAAAATCAAAGACACTGGATTGCCAGAT +AATAAGCAGTTTCTTTTATCTGTAAATTGAATTTACTTTTCCAAGTTTTATGCTTATTTT +ATGTTAAATATGTGCTTGATAAACAAAATATGGTATACTTTTTTTAATTAACACTTTTTT +AAAAAGGACCTACTACTAACAGGGAAATAGCTTATTTTTCTTCAATGAAAAAGCTAAGGC +AGTAAAAAGGGTACCTACAAAATAAAAAGCGCTATTATAATGGGAAATATTTTAGATGTA +CATGTATTCATTCACTTATTCACAAATTCAACCAACATTGATTACTTGCTATGTGCCAGA +TACTGTACCTGTGGAACATACCTTTGATTTATGTGCTTGATGAATAATCTTTAGTGCATC +TGAAAGAAAAAAGCAAGTTATCTTTTTACACAGTTTATTCTAAACTTCTTTTCAAATTAT +TAAAATGGGTGGAGGGTGGCTACGAAATTGAGAAATGTAAGTCCTTGTTTTATAACCAGA +CTCATTTAGAAATATACTATACAGCAAAAGAAAAATTACTTCTGTAGATCATTAAAACTG +AAGTAAAAGATCTTTATCTTTTAAAGCCTTGGTCTTTGACACACAGCAGTGTGTGTGTCA +GAACTTTTTGTCAACTCAGCACATTTTTTCTTAGAATGGAAGACAAGCAAATCAGATTAC +TGTACCTTGTTTTTTTGGAGTCAATACAGAACAGGATTAGCAAATAATGTAAAAAAAAAA +GTCTTAAAATAGACATTAGCAAATGCAGTTCAAAAAAATCTATTCAGATGAGATATAATG +ACAAGAGAGCAAATGATGATACAGGTGTTGCCACTCTCAGTATTCAAACACTGTATCTAG +GACCACCGGGAATCTGAGCAAGGCTGCTAATGCCCCAGGAATATCACTATCTGTCTCTTG +GTTTGCAAATACTGCACAGGCTCACACCATTTCATCTGCTCTATTCAAACCCAACTTCAC +TCCTTAATTTGTTTATCTTGAAGTCAGGCTACACTGTGCACTTCCAGTAAGTAATTTCTC +CACACTTGGGTAAAATTCGAACTCAGCAACAATCAGCCCTTAATTACATAATCTACACAG +CCATTCAACAGGTTGAAATTCAGAAAGTTTCCGATTCTTCACTCGTTTTTATTTAAACAT +TTAATGAATGCATTATGATTACAGTGTATTATTGAATAAACTCCCAAACTTAAACTAAAA +CTCATTCCTATCAATCACGTTGTAACAAGGAATTCCAACAGTGACAGGAAATGAAAGGAT +CTATTTTTAAAACAGACCTTATTTAACTATGTTCTCATAATACACAATAAGGTGGCTATC +TAGATAAGAACTAGCACTCTGAATTTGCCCATTATTTTAAATAGTCAACTTTCAGTTATC +TATTGCAATTTTTTTTTTTTTTTGAGACGGAGTCTTGCTCTGTCGCCTTGGCTGCAGTAC +AGCAGCATGATCTCAGCTCACTACAAGCTCCACCTCCCAAGTTCAAGCAATTCGCCTGCC +TCAGCCTCCCGAGCAGCTGGGATTACAGGCTCCCACCACCACACCTAGCTAATTTTTGCA +TTTTTAGTAAAGACAGGGTTTCACCATGTTGGCTAGGTCTCGAACTCCTGACCTCAGGTG +ATCTGCCCTCCTCAGCTTCCAAAGTGCTGGGATTACAGGCATGATCCACTGCATCTGGCC +TTGTAATTTTTTATACAAGGTCAACATAATCCTCAGTAACTCTGTATTCCTAAGAAATAA +AAATAAATCTAACCTAAGTAAAATATGCATATTAGGGATGTAAATAAACCATAATTGCTA +AAAATAAGCTTAAAATGTGTGTAAGAAAATAAACAAAGTTGACTTTCAGCTTATCTAGTA +TTCCAAATTACCTATCATGTCCTTTTTCTTACTATAGATATGTTTATTATTTGAGACAAG +TGAGAGAAGCCAATAGTATTTTTAAAATAACAGGAGCTCAAAGTCTGTTGCAATCAACCT +GCAAAACTATAGTCTGACCTTACTAAATATTAATCCTGTTCTATATATTTTGCTAATGAG +CCTTTAAACTAGAAATCCTGCTGCTCTAATAGGTTTGGCAAACACACAATTAAACGGCTA +CATATTTTAGCAGAAAAAGAAATGTTTTGAAGAGAAGTTTTTGCCAGATTTTTCTCTCCA +ACAGAAAGGGGTGTGACCTGAGGAGTGGGTAAGAAAGGAGAAATGACAAACCAGCAGAGA +GATGTATTACTGTCCCTTTCTGTGTTGAATAAGCTGCTTCCCTTGTTCTTGCTTCTTTCA +AATAATCCTCATAATTATCACAAACAATACCTGTGGGCATTGTTTTCTTAATACAAATTC +CTTGAGGAAAGCAACCTCATAAAAATATCATCTTGTATTTGTGGAGCATCACACACAGCT +TTATGAAACAGAGAGGGATGAGCAGCCCACACTGTACAACAACTACATTCTTGTGTGCCC +TCATGGGTCATGTCTAGGCGATAGGGATTTAAGATAAGTAGCATGCGTGGTAAATCAATA +ATAGATGTGGATGCCAATTAAATGGGAGGAGGGCTCTGAGATATCTCAGGCTCTTGGTGG +CAGAGAGAATCAGCCCTTTGCCAAAGGGTAGGGAGACAGTGACTGGCAAAACTGAAATCT +GACTCCACACTCTTTCCACTCCCGAATACCTAACAAAGTGCCCTGTCCCGCAGACCGTGA +GGTGGCAGTCCCGGATGACAATGACAGGTGAAAATAACACTGCAGCCTTTCTTGTTCAAC +AGAAAGCAGAAGATTGTTAAACAGCCAAGTTCAGACAAAGCCACTTGAAGTCTATCAAAA +CTCGAGTGGTTCTATAATTTCTTCACAAATAAATGTATTCATTTTTTCTGCCAATTCATC +TGAATAGTATAGAAATACTAGGGCAGAAGGAAGTTAATAAGATAGAATAGTCTAAAAGGT +ACATTATCTACCACAATAATGCTTAGCAACTTGGATATTCTAACGCTTTCATTATCTAAA +ATTTCTTTCAAAAGAACTTACATGGAACACAGCTTTGCACATAGACATATAGATACACAC +ATACACACACACCATGAAAAAAGGAAACCATATGTAACTATTCTAATTTAAAATGGCATC +TGTAAGTTGATTCAAGTTTAAGGCTATATTTCAAGACATTATACTTTGAAAGCCTTGAAA +GCCACAATTGAGAAGTTTCATATTTACCTTAATCATCCTTTTTATTCCTTTATCTTATTC +AATATTGAGTATGTAAATTCTTTAAGCCCAATAAATCAAAGTACTTTCCACTCAGTGCCT +TCAACTTCTGCTTCACTACCCCTTATAACCTCACAATTAGTTTCTGGATATTAAAATGCA +TACACACGGCGAAGATTGTGATTTCAAAGGATTTTAGGTCATAAGTTGTTCTATCAAATG +AGAACAGAATGAAAAGCCACTCCAAAAAAAAATCTAAGGTAATAAAAAATTTATACTTTA +AAATGTCTGCACCAATTAAGAGAAATATTTATTAGGTGCATCATACCTTTCAAATGAAGT +CTCAAATTCAAAGTTTGGTGAGTGTCACTCTGCTGAAGGTTAATAACTGTGCCATCTTTA +TAACAAATAATGAATGACAACATCTAGCTTCTTACCTTATTACTCCATTTTTAAATCATC +AATTGTAACACATAAAACTACTATATAACATGCTCAAATTATTGGCATTTAAAATGTTAA +ATCCCTTCTTTTAATTCTTAGTCTTCAATCATTTTTCCTTTTCTAATTACCTGGCAGAGA +AACTCGTTTTAAACACAGTTTTGGCAAACATGCTACTCTTTGCAAATACGCCACTTCCTT +ACTATTACAATTCATTTCAGCAATATACTAGCATTCCTGTATTTCTAAATAAACTTCCAA +ATTGGTTTTTATTTACAGATAGTCATTTTTGAAAACAAAATTTAAGTTTGTAACAAACTA +ATGCAAAATTGTATTTATATATATTTTAAAAGAATAAAAAAATGGTTACCATATTTATAA +TTTCTGAATGGTGGTGGCAGGTTGGTCCTTAAAGGGATATCTACAAGAGAAAGATTATTT +TTTTACACAATAAGCAAATAGACACTCATAGAATATGCACAGTCTTTTGGTTCTATTCTT +TTCTATCTACAGACTAAGTTACCTTGAAAAACCTGACAGAACACAGAATAAATACATCAC +CGAAATCCAAGGGCCATCTATATTAGTCCATTCTCATACCACTATAAAGAAATACCCAAG +ACTAGGTAATCTATTAAAAAAAATGTTTAATGGACTGGGGAGGCCTCACAATCATGGCAG +GTGAAAGAGGAGCAAAGGCACATCTAACATGGCGCCAGGCAAGAGGGTCTGTGCATGGGA +ACTGCCCTTTATAAAACCATCAGATCTCACGACACTTATTCACTACCGTAAGAACAGCAT +GGGAAAAACCCACCCCCATGATTCAATTCTCTCCCACCAGGTCCCTCCCCTGACAGGTGG +GGATTATGGGAGCTACAATGCAAGATGAGATTTGGGTAGGGATACGGCCAAAGCATATCA +CCATCTAAAATATTAGAGCTATTGACAAGATGTTGAGTTGTTACTATCTGAACTAAGACT +TCAGTAACACTATTAAAAGAATGTTTAATTTCATTAGACAACAGTATCTATGTATAGTTA +AAATATATACTAATACACTTGTGTGAGACATATATATATATATATAGCTGATGTTTGTTT +AGCATATGAATCTGAGAGCCCCTTATGGGTCTTTGGCCATTAGTGGAAACCAATGATCTA +GAACAATCTTATTACTCCACCAAAATTCATATAACCAACAAAATAACTCCTCTAACTCCT +CAAAGACAACAAAACACAGTAAATATTCTTTTAAAAACATATTCCAAATGCCAGTACTAA +TTTTAATTAATATCTGCTGGTACAACACCTAACAGAGAAATGTGTGTATATATGTGTATA +TATATATATATCTCAAAATTACATATGCACATACTCCTTGACCTAGCCATTCCACTTCAG +AATCAATGAGTGAATGAACGAATTTATTGATTAACTGATTGACACAGGGTCTCATTTTGC +TGCCCAGACTGGAGTGTAGTGGAACAAACATGGCTCACTGCAGCCTCGACCTCCCAGACT +CAAGTGATCCCCCTGCATCAACCCCCCAAGTAGCTGGGATTACAGGTGCATGCCACCGCA +CCCAGCAATTTTTTGTATTTTTTTGTGGAGATGGGGTTTTGTCATGTTGCCCAGGCTGGT +CTCAAACTCCTGAACTTAAGCAATCTGCCCACCTTGGCCTCCCAAAGTGCTGGGATTACA +GGCATGAGCTACTATGCCCAGCCGGAAATTTATTATCATAGAACTATACTACACACGAGT +GTGTGTAAAATGACATTCATAGAAGGGTATTAACTGCAGCATTGCTCACAGCAGCAAATG +TTAGGAAAAGTCCAAATGTCCTTCAATTAGGTACTCGTTAAGTAAATCATAATATGCCCA +AACAATGAAAAATACTTTTCAACTGTTAAAAGAAAAAGAAGGAAGCTCTCTACTAACATG +ATAAGATCTTCAAGTTACATCAAGGCTAAAGAGATATGAGAGAACATTATTTTTAGGAAG +CTACCTTTTGAGTAAAAAGGGGGTAAAATGAGAATTTATGGTGGGATTTGCTTGTACTTG +CTGAGTGGGGGGTGGGGAGGGCAGGGGGGTGCTGCACTGGTCAGACAGAGACCAGAAGGG +TAAAGGAGACTTTTCACTATATTCCTTTCCACATTTTGATCTTAAAACCACATGAATGTG +TTACCTACTAAAGAAAAGTAAAACAAACAAAAAATATCCACGTATCTAAATTAGGAAATG +TGAAGGTTTTTGAGACAGGGTCTTGCTCTGTTGCCCAGGCTAGAGTGCAGGGATGTGATT +ATACTCACAGTAGCCTTGACCTCCTGGGCCCAAGCGATCCTCCCACCTCAGCCTCCCAAG +TAGCTGGGACTACAGGCGCTCAGCACCATGCCCATAGTCCCGGCATTTTTTTTTTTTTTA +ATAGACAGGTTTCACTAGGTTGCCCAGGCTGATCTAAAATTCCTGGGCTCAAGCAATCCT +CTCACCTCGCCCCGAAAGTGCTGGGATTACAGGCATGAGCCACTACACCTGGTCAGGAAA +TGTGGGTTTTTTTAAAATGCTTTTTCAAGATCAAATACGTATCAAATTAAAATATAATTG +ATTAATTTATGTTACAAGCATTTAAAGCACCTACTACCAGGTATTCCAGGAACAGAGTAA +AAGAGGAGCTGCCCACTCATGACAGCGTGTGCTCCAGTGGTGAATGCTGTAACAAAAGTA +CGTTTCCAGCCAGTGCTATGGTCCTAGGAGTGTGGTCCTCACCCCGGCTGCACGTCAGGA +TCACCCAGCCTGGCACGAGTGGATCTGACTCACGGTAGGCTGGTCCCAGGCAGAGATATT +TAAACACAAAACAAAACAAAACAAAACAAAAAAAACCCTGAGATGATTCGTACTCAAATT +CACCCAGAGGCCAGACAGGTGACAACAGGTAAGTGAAGCAGGTCAAACAAGGAGGGGCAG +TGAGATCTGAGAGCATGCGCCCATCAAAGGGGGCTCTGCCAGTCAGTGCTGACTGATCAC +AGTGCTGTAGGAACATGAGCCTGGAGTGGCCACACCTAAAGATTTAAATGGCAATGCTAC +AAGTCTAGGGTTTTAGGTGAAATTTCTTGACTTTTAAAACACTATAGGCCAAAAGAAACC +TCTCTGGAGGCAGGATTTGCCTGCCAGATACCAATTTGAAACCTCTGGCTTAGGCTTACC +AGAGCATATGTACTTCATTTTATTCTTCTTGTGTCTCCATTATTTGTGAATTATGGGCCA +AAGCAGTATTCATTCAACATCAGAAAGGAGAATTAATTCCATTTAATGTATTGACATTTA +TATTTCCTGAATTAGACAATGAAACTCCCTGAAGAAAGCCGTGAGGTGAAGAACAGATGG +CCCCATGAAGCTATTATCATTTAGAGATGTCTACGACTGAAGAAATCAAATCAGTCTTAT +GTTCAATCCAGACTTCTGAGAGAAGAGACAACGACCAGGACACAGCGAGCACCTATTCTC +TTCCTGCCTTTACATCTTAACTGAAGTGCCATCTCCTCTGACAACCCTTCTAAAGCGGGG +GTCTTCTCTGATATTGTTTCCTTCATAACAGGTTTTACAATTATAGTTTTGTCTTTTAAC +TTATTTTTGTCACTATTTCCTATGAATTTATAAATTCCTCGGGATGAAAACGTGGGCTGT +CCTCTCAAAACCTAGGACCATGTCCGGCCCATAACAAATTATCACAAACTGCTTCCATGA +GGGCAGGGACCACAGCCTGTTTTCTTCATTGTGTTGTCAGAACCTAAAATAGTGCCTGGT +ACACAGCATGTGCTCAAAATATTCATGAAAGAATACATATAATTTAATGCCTACAGTTGC +CAGTGGAGAACACTGAGGTCTCAAGAAGTGCCTGGTCAGCCCAAGGTGTCAAGAGCTGGG +ACCAGAACCCTGCCCTCTCGACTCCCCTCCTGCAGCACTGAGAAGGGTGGGAACTAAAGC +AGTTACCTTCCACAGTGGCAGAAAGACAGATTAGACATTAGACACACTCCAGTGAGATAA +GAGCTTTAACCAAAATACATATAAAGATGCCTGCAAAGGAACTGGAAAAAAACAAACATG +TTCTTTATGCTAAAGGTCATTTTTAATCTTGCGCTATTACAAATAAAGCTGGGAACATTC +ACATGGAGGAAATTACTTTCATTCTCACAGGCACATACTGTCATTCCACCTAGAAGTGGA +ATGGCTGGATCATACAATAGGTATATGTTTAGCTTTCTAAGAAATTGGTGGCCGAGTGCA +GGGGCTCACACCTGGAATCCCAGCACTTTGGGAGTTCAAGGCAGGAGGATCGCTTAAGTC +CGGGAGTTCAAGACCAGCCTGGACAACATAGCGAGACCCTGTCTCTACAAAAATAAAAAT +TAAAAAAAGACACACCTGCAATCCCAGCACTTTGGGAGGCCGAGGCGGTTGGGCCACCTG +AGGTCAAGAGTTCGAGACCAGCCTGACCAACATAGTGAAACCCCATCTCTACTAAAAATA +CAAAAATTAGCCAGGCGTGGTGGCGGGTGCCTGTATTCCCAGCTACTCAGGAGGCTGAGA +CATGAGAATCGCTTGAACCCAGGAGGCAGCGGTTGCGGTGAGCCGAGATCTTGCCATTGT +ACTCCAGCCTGGGCGACAGAGCAAGACTGTCTCAAAAAAAAAAAAAAAAAAAAAAAGACA +TGATGATGTCTGTAGTCCCAGCTACTCAGGAGGCTGAAGCAGGAGAATCACTTGACCCAT +GAGTTAAGGCTGCAGTGAGCTATGGTTGCACCACTGCACTCTAGCCTAGGGGAGACAGAG +CAACACTGCCTCCAAAAAAAGGAAAGAAATGATAAATCATTTTCCAGAGTGGCTGTTCCT +TTTAATATTCCCACTAGTGGTATATGAGAGTTCCAATTCTTCCACATCCTAGCCAAAACT +TCCTATGGTTACTCCTTTTAATTTCAGTCATTCTTATGGATGTGTTGTGTAATCTCATTG +TGGTTTTAATTTCCATTTCACTAAAGACTAATGATGAGTATTAATTAATGTGCTTATCTG +CCATACATACGTCTTCTTTAGTGAAGTGTCCGTTCAAATATTTTGCCCACTTTTAATTGT +GTTGTGTGTCTTATTATTGAGTTATAAGAGGTTTTGGTTTTGGTTTTAATTCTTATTATT +CTAGATAATAGTTCCTAATAGTTCCTTGTTGGATGTATGTTTTACAAATATCTTCTCCAC +ATCTGTGGTTTGGTTTTTCATTTTTTTAGTATATTTTGAAAAGGAAAAGTTTTTAATTTT +GCTAAAGCCCAATTGATTTTTGCTTTTATAGTTTATGCTTATTGTGCTGTATTTAAGAAA +CTTTTACCAAAATCAAAGTCTCTAAGGTTTGTTGCTGTTTTCTTCTAGATGTTTTATAGT +TTTACCTTTTACATTTAGTTCTTGGCCAATTTTGAGTTATTTTTGTATATGGTAGGAGGT +AAGCATTGAGGTTCATTTATTTGCATATGGCTATCCAATTGTCCTAATACCTTGCTTGGG +AAAATTACACTCTCCTCAAAAATACCTTGAGCAAAAATCAATTTAACACATCTGTGTGTC +TGTCTCTGGACTCCGCTTCCATTAACGTATATGTTTATCTACACACCAGTATCACATATG +CAGTACTTGATTACTATAGTTTTATAGCAGTAAGTCATGAAATAAGGTAGTGTAATTTCT +TCAACTTTTTTCCTTCTTTTTGTGAGTTATGACGATTTTAGGTCTTTTGCCTTTCCTTAC +AAATTTTAGAATAAGTTTGGTATTATCTGAAAGGAAAAAAAAAAGCCTGCCAGAATTTTG +ATTAGAACTGGAATCAATACCACAGTTTGAGGACACATGACATCTTAACAGTTTTGAGTT +TTCTGATCCATGAACACAGTATACCTCTCCATTTACTTAGGTCTCTAAATTTCTCTCAGT +GATATTTAAAGTTTTTAGAGTAAAAGTCTTACACTTCTACCAAATGTATCCTAAGTATTT +CAGGTTTTTTGATGTTTTATCATTTTTTTTTCAGTTTCCCACTGTATATTGCTTGTAACT +AGAAATACAATTAATTCTTGTACACTGATCTTATATCTTAATATCTTATAACCTTGCTAA +GCTCAGTTTGTAAGTTCTGGTAGCATTTGTATAGATTTCATAGGATTTTCTGCATAGATA +ATCATATTGCCTGTGAATAATGACAGTTTCACGTCCTCCTTTCAAACAGGGTTGCCTGTT +ACTTCATTTTCTTGCCTTAATGAACTGGCTAGAACTCCAGTACAATGTTGAATAGCAGTG +ATGATGAACAGATGTCCCTGCTTCCTTATTTTAGGAGGAAAGCACTCAGTCTTTCACCAT +TAAGCATGATGTTAGGCAACAGTTTTTCATACTCTTCATCAGGTAGAGGAAGTTCCTTTT +TATTCCTAGCTTGAAAAGAGTTTTTAGCAGGAATGGATTTTGGATTCTGTCTTCAATTAA +AATAATCTTATAGTTTTCTTTTCTTTACTATTAATATGATGAATTACATGGATTTTTTTT +TTTTTTTTTTTTTTTTTTGGTGGAACCAGCATTGCATTCTTAGGATAAACCCTACATGGT +CATTGATATAGTTTGGATGTTTTGTCCCCTCCAAATCTCATGTTGACATGTAACCTCCAA +AGTTGGCGATGAGCCTAGTGAGAGGTGTTTGGGTCACGGGGGTAGATCCCTCACAAATGG +GTTGGTGCTCTCCATGCTATAATGGGTGCGTTCCTCCTCTATTAGTTCACGTGAGATCCG +GCTGTTTAAAAAGAGCCTGATATCTTCTCCCTCTCTCTCTCTCTTGCTTCCTCTCTCATA +TGGCATGCTATGTGGCATGCTGACTTCCCTTTGCCTTCCACCATGGTAGTAAGCTTCTTG +AGGCCCTCACCAGAAGCACATGCCAGCACTAAGCTTTGGGTATGGCTTACAGAACCGAGA +GTCAAATAAATCTCTTTTCTTTATAAATTACCCAGCTTCAGGTATTCCTTTATAGCAATG +CAAACAGACTAACAGAGTCATAATGTATTATCCTTTTTAAATATTGTTGGATTTGATTTA +CTAAAGTTTGGGCAAGAATTTTTACATCTCCATTCATGATGGATATTGGCTGGTAGCTTT +ATTTTCTTTCAACAACTTTTTCTGGTTTGGTATCAGGGTAAGGATGACCTCAGAGAATGA +GTTGAAAAATATTCTGCCCCCCTCCTTTTTTTTTTCTTAAGAGACAGTATCTCGCTATGT +TGCTTGGGTTGTTCTCAAACTTCTGGCCTCAAGAGAACCTCCTGCCTCAGCCTCCTATAT +AGCTGGGATTAGAGGCAAGAACTATCGTGCCTGGCTCCCATCCTTCTTCTGGAAGAATCT +CTGTAGAATTGAGATTATTTCTTTCTTAAAAATATGGTAGAATGTACCAGTGAAACCATC +TGGGCCTGGAGTTTTCTTTGTGGAAGTATTTTTTAACCATAATTCCTTTTAAAATACAGA +GTTGTTCATGCCGTTTCTTTTTTAGTGAGCTTTGATAGTTTGGGTCTTTGAAGCAATTTG +TCCTCTTTATCTAGGATACTGTACTTATTAGCATTAAATTGTTAAGAATATTCCTTTATT +ATTCTTTTAATATCTGCAGAAAGTCTGTAGTGATATGACAACTGTCACTCCTGATACTGG +TAACTTGTATCTTCTCTATTTCCTGATCAGTCTGGCTAGAGTTTACTCAATTTTATTGAT +CTCCAAGAATCAACTTTGACTGTTATGGATTTTCTCTATGGTTTTTCTATTTTCTGCTGT +GATCATTATTATTTCTTTTATTCTGATTATTTTAGGTTTCATTTGCTTTTCTGTTTCTAG +TTTCTTAACATAAAGACTGAAATCATTGATTTGAAACCTTTTTTAATATTTAGGTGTTTT +AGTACTATAGACTTTCTTTTAAATACTATTTTACATGCATCCCACAAAATTTGAAAAGTT +GTATATTCATTTCCACTCAGTTCAAAATACCTTCCCTTTTGATCTCTGCTTTGACCCTTA +GGCTATTTAGAAGTGTGTTATTTGGTTTCCAAATATTTGGAGATTTTTCCAGAGATCTTT +CTGTTATTGATTTCTAATCTAATTCCATTATGGCCAGAAAATAGACACTGTCTAATTTGA +ATCCTTTAAAATCGATTAAGACTTGTTTTATAATATGAAATCTGGACTATTCATAAACGC +TCCATGTGCATTTGAAGGAAATGTGTAAATTCCACTATTGTTGGAAGCAAGATTCTATAG +ATGTCAATTCAGTTGATTGGGTTGCTAGTGTTTTTAAGTTCTCTTGATCCTTACTGATTT +TCTATTTGTTCCATTCCTCTATTTCTTCCTGCAGTTCTATGAGTTTTTACTTCATTTATT +TTGAAATTCTGTTGTTAGGTGCATCGTTATGTCCTCTCAGTTGATGCCTTTATCATTATG +AAGTGATAGTTTTATCCCTAGTAATATTTTGCTCTAAAATCTACTTCATCTGATACTAAT +ACAGTCCCTCCACTTTTCTTTGGATTCATATCAGCATGGTATAACTTTCTCATCCTTCTA +TTCTTACTTGATTTTTATCTTTAAAGTACATTTCTTGTAGGTAACATATAATTGGGACTT +CCTATTATATGTCTGTCTTTTAATTGGGGTATTTAGACCATTTACTTTCAATGTGATTAT +TGATATGGTTAAAGTTTGCTATTCTTTTAAATTTGTTCTCTATTTCCTCTTTTTCTATCT +TCTTTTGGATTGTCTATTTGACAATATTTTATGATTCCATTTTATCTCTTTTTTTAGCTC +ATTAGCTGTAACCCTTAGATTGTGGGGTTGGGAGGCAGGAGTTGCTTTGAGGTTTACAGT +AAACATCTTTATCGGTCTACCTCCAAATGATACTATAACACTTTGTAATAGCAAAAGATT +CTTCCATTTCTCCTCTGCTGGCCTTTGTGCTACTGCTGTCATAAATTTCCCACAAAACCC +ACAATACGTTGTTGTTGTGTTTCTTTAAATGGTCAAATATTTTTTTTAATTATTTTCAAA +ATAAGAAAAAATATTTTATATTTATTATATTTACCATTTCCAGTACTCTCTATTTCTCTG +TGTGCATCCAGATTTATATCTGGTATCATTTTCCTTATGCCTGAAGAAGGTCTTCCAACA +TTTCTTACAGTGCAGATCTCCAGGTGATGAACTCTTTCAGCTTTGGTATGTCTGAAAACA +TCTTCATGTTGGCTTCATTCCTTAACTGCTTTAAAGAAGTTACTCCAGGCCAGACACAGT +GGCTCACATCTGTAATCTCAGCACTTTGGGAGGCTGAGGAGGGCAGACCACTTGAGGTCA +GGATTTCGAGACCAGCCTGGCCAGCATGGTGAAACCCCATCTCTACTAAAAATACGAAAA +AAATTAGCTGGGCGTGGTGGCACATGCCTGTAGTCCCAGCTACTTGGGAGGCTGAGGCAG +GAGAATCGCTTGAACCTAGGAGGCAGAGGTTGCAGTGAGCCAAGATCATGCCACTGCACT +CTCCATCTCAAAAAAAAAAAAAAAATGTTAATCCAGTATCTTCTTTCTGGCACACACTGA +TTCTGATGAGAAGTTGGCTGTCAATTTCATCTTTGTTCCTTTTTATGTAATGTGTTCTTT +TTTCTCTTGCTGTTTTTAAGATTTTTTTTCTTTACCACCAGTTAAGCAGTTAGATTATGG +TATGCCTTGGTGTGGCTTTCTTCATGTTTCTTTTGCTTGGGATTTGTTGAACTGCTGGGA +AATGTGAGTCTCTAGTTTTCATCATATTTGTAAAATTTTCAATCATTATTTCTTCAAATA +TATCTTCTGTCCCCCGTCCCTCTCTCCTTCACTATCTCCAATTACATGTATATTTGGCTA +CTAGAAGTTGTCCCATACCTCCCCACTGCTTTATTTTTTCCAGTCTTTTCCTGTGTTTCA +TTTTAGATTGTTTTGTTGCTATGTTTTCAAGTTGACTAATTTTTTTCTCCGCAGCATCTA +ATCTGCAGGCTAATCCTGTCCAGTGTATACCCATCTCAGACAATATTTTCAATTCAGGTA +TTTTTAAATATCTTCCATTGCTAACATGCTCAATCTTTCCTCTAGCTTCTCGAACATTTT +GCAATATGGTCATAATTATCTCCATCATCTTTGTTTACTAATTTTATCACCTGCAATATT +TCTGGGTTGGTTTCAATAGACTGATTTTTTTTTTCTGCTCATTATGGGTCATACTTTTTT +GCTTCTTTGCATGCCTGTTAAGTTCTGATTTGATGCTAGACACCGTAAATTTTATCTTGT +TGGGTGCTGGATATTTCTGTATTCCTGTAAGCTTTCTTGAGCTTTCTTCTGCAACACAGT +TAAATTACTTGGAAACAATCTGATCCTTTCAAGTTGTGCTTCTGAACTTTGTTAGGTGGG +ACCAGGACAGAATTCAGTCTACAGCTAATTTTGCTCTACTACTGCAGCAACACCCTTCTG +GATACTCTGCCCGATAACCTGTGAATAACAAGGTTTCCACTCCAACAGGTGGAATAAAAA +CTATTCCCAGCCCTGTAGGAGCTCCGAGCATTTCTCATTCTACTAGTTTTAGGTGGTTCT +TTCCCAGGCTTCCAGTGGTTTCTTTACTTGCTTGCACTGATCCATACACAACTGAAGACT +CACACTCTGCATATCTTCAAAGATCCTCTGCAAATCTTCAGAGCTCCCCATCTCTCTGTG +CAGCTCTCTATATCCCTGTACTCTGCCCTGTGAACTCTCCAGGGTCCACTCCAGACTGCC +AGCTCTGACTCCTAAACTCATGGAACCCACCAGCTTTGCCTGAATTCCCTCTCCCCGCCC +TGTGGCCTGGAAAGTGGCACAATCATAGGGGTCACCATGTCTGTTTCCCCAATCCCAGGG +AAATGATTGTTTTATATATTATACATAGTTTTTTTAGTTGTTTAATGTAGAAGAGCAAGC +CTGGTACCCTGGTCCCACTCCATCTTGGCTGAAAGCAAAAGTTTATGACGTATCTATTAT +ATTCTGAAAATTATTTCCCACTTTGCACTGCGTTTTTCTTTCATTTTATGTTTTCCCACC +TTTGAACTTAAGACTTCAGAATGTTGCAAAAACTAATTTAATATTTCATTAATAGAAAGG +AAGGTCACGAGAAGGTAACCACTAACTTTTCTCATACAATTAAGTCTCCATAAAAAAAAA +ATCAGTGGAAAAATTTAGGCAACTTAACAAATATACTACTGAAAATTACAATGCCCCAGG +GGAGTCTGAAATGTTAAAACACACATTTCAATACAAAAATCAATAAAGTCTAGAAAACCA +TTGAAATATCAAGAGGCAATAAAATAATTCTTTGCCTCACAGTAAAGGCTCTAAAAATAG +AAGTGGTACAATTTGTAACTTATTATTGGATGCTGGATCTACATTAGAAGACCTTTGAGA +AAGCATAAACACCTAAAGGAAAAAAAAAATAAAACTAAGCCAATGACTAATCTATATGGA +CAAAGAATACCAAACACCTAATAATCAAAACTATGCACCAACATTCAAACCTGATAAGGT +ATCCTTATCAGATATGATGGTAAGATTCAAAGGTTAAGCTATATGCTTTTTACTTTAATT +ATAAAATAATCTAAATTATAGAAAAGCACAGAGTAGAACAAAAAATTCACTTAACCCACC +AACCAGATTTTACAAATGTTAACATGTAGTCATATTACTATAGATCCTTTATTATTTTTT +TTAACTAAGTAAAACAATCTGGATGCAGCTAAAGCCTTTCTATCTTTTGCCAGTCCCACT +GTTACTCCCTTCCTAGAAGAAACCACCTGCCATCCCTAGGTTAGCACACCCGCTCTGTTG +TTTTACTCTCGTTCCAAAGACTAATAGCCAGGGATGATAAAAATAGTTTTGTTTTGTTTT +GTTTGAGTCAGGGTCTTTCTCTGTTGCCCAGACTGGAGTGCAGTGGCACAATCAAGGCTC +ACTGCAGCCTCGACCTCCCAGGCTCAAGCAATCCTCCCATCTCAGCCTCCCAAGTAACTG +GGCTACAGGCATGCACTACAAAGCCAGGCCAATGTTTTTACATTTTTAGTACAGATGAGG +GTCTTGCTATGTTGCTCAGGCTGGTCTCGAACTCCTGCATTCAAGTGATCCTCCCGCTTT +GGCCTCCCAAAGTGCTGGGATTACGGTGTGAGCCACCACGCCAGGCCAAGTATTATTTTG +TGTATTAAAATTATAAAGTACTTAAATTAAAGAATGCGCAGCACATCCTGTAGTAGAGTA +GTAAAAACAACAAAGCATTGCCTTAACAGTATGTTGAAGGAACTGCCTCACGTGATAAGG +CAATAATACATTATGACTGTGCTGCAGCCACATTATTGTATTCCTTTCAAAAAAAGAGAG +GCTTCAAGGGACGGGTTCTCTACAGAAGAGTGCCAGATAATACATGTAGAGATAATCATA +GAATTAGAAAAATCACAATTTTTCAACCACCAATGATTCAGATAAGGATCATCAATAAAT +GCTAAAACCATAAGAAACAAGATATGTAAATGGTCTCAATGTTGATCACTCCATAGACTA +CTTATAAATTAGAAAGACACTTTAACATCAGGAAAATCTGGTGGATGGCACCTTTAGCCA +AAGGATTTAAATCTGTATCACCAATGAAGGCATAAACTGACATTCAGTGTTTCCTGATGT +GATGCAACAAGGAGGAATCACCTACATCAAGGCCAGCAAACTAGTTTGGTAAAGGCCAGC +GAGTCAGCATTTTAGGCTTTGTGGGCCAGTCTCTGTCTCTGCGACAGTCTGTCACAACTA +TTCAACTCTACTACTAAATCACAAAAGTGGTACATATATGGTCCACAGACTGTTGTTTGT +TAACCCCTGACCTACATGGTAATCCTGCCAAAACTGCTTAACCCGAACCTAATCATGAGA +AAACAATCTAGACAAATGTAAATTATGTAACATTCTGTAAGACACTGGCCTAAATTTTTC +TTTAAGAATCAATATAATGAAAAACAAAAGGTGGGGGATTGTTCCAGATTAATGGAGATT +AGAAAGATATGACCTGTCACAAAATGACATGAAGGACCCTTCAATGCGTGTTCAATGCAT +GTTTCTCTGTTCTTTTTTTCTTTTTTTTTGTACAGATGGGGTCATACTGTGTTGTCCAGT +CTGGGCTCAAACTCCGAGGCTCAAGTGATTTTCCTACCTCCACCTTCCAAAGTGTTGGGA +TTACAGGCATGAGCCACTGTGCCTGACCCCTTCAATGTATATTTCTAAGTAAAAGAAGCC +ATTCTGAAAAGTCTACATACTGTATGATTCCAATTCAGTGACATTCTGGAAAAGATACAG +AGATAAGAACAAAATCAGTAGTTGCCAAGGGTGCAGCATGGGGAGGGAAAGGATAAAGAA +GTGAAGCACAGCGGATATTTTAGGCAGTGAAACTATTCTGTACGGCACTGTAAGGGTGGC +TACATGACATTACCCATTTGTCAAAAACCCAAAGAACTTTGTAGCACAAAGAGTGAACCT +CAATGTATGCAAAGCAAAAAAAAAAAAAAAAAAAAAAAAAGGTCGGGCACAGCGACTCAC +ACCTATAATTCCAGCACTTTGGGAGGCCGAGGCAGCGGACTGCCTGAGTCCAGGAGTTTT +GAGACCAGCCTGGGTGGGCAACACAGCAAAACCCCGTCTCTACTAAAAATAAAAAATTAG +CCAGGCATGGTGGCATGCATCAGTAGTCCCAGCTACTCAGGAGGCTATGGTGGGAGAATC +ACCAGGGTCCGGGAGGTTAAGGCTGCAGTGAGCCGAGATGGTGCCACTGCACTCTAGCCT +GGGCAACTGGAATGAGACTCTCTCTCAGAAAAAAACAAAATATATATATATATATATTTA +AGAAGTCAGAGGATACCAGGAAAGAATGCAGGTGGTGACAAGAGAATCTAATCTATCTGT +ACTACAAATGCTACAACAACCTTACTGAAGGGAGTAGAAGAAAAAGTGCTGACCTAAATA +ACTCTGGCAATGAACAGATTTTGTAAGACTACAGTGCTTATGGCGAAAGGACACAAAAGG +ACTGTATCTAACTGATATCAAGTTGCTTCCCATGGGGATACACTGCTATACCTGTATGCT +AGAATTAAACAATTAAATAAATGGATAGCAGATGGTGGGACCACGTTTCTCACTGTTGGT +ATGGGAATTAACAGATAAGCAAGGAGAGGAAGCTAGAATGACCCACAGGGTAATGGATCA +GAGATGGAAAGATCAGTAAGAACTCACGTTTAATGTATTTGTATATAGATCATTACATAT +AAAAATATTTATAGATATGTACATACGCACAGGTTAATACAGACACATATATTTCTTTGC +CTGATCAGCTGAGACAGTTTAAAATAACACTCCTTGGCCTTTAGATATCTACCATAGAAA +AAAGAAAGAAAGAAAGAACACTCTAGTAGCAATGAACACATCTAGTACCTAGATCCTGGT +TTCTAACACAATTTTCCACTAAAAAAGAACTGAGACTCCTTGGAAATAAAGCTGATTCTA +AGAACAGGGCATGTACAAGATGAGTCTGGAGCATCCTGTAGTACCAGAAAGTAAAAGTAC +TGAACACGTGCACCCATGCACACTGAGGGCATATGTCAGAGGAGCACAGAAGGCAATTGA +AAGAGCTCCCAAACCTAGCAAAATCTGAGCAACAAAGTCAAGTCTGCCACACAGAACTCC +AAAGGATTTTTGTACATGGTTTATTCTAAAGGAAGGGAAGCATAACTCCCGAGTGTTTAA +CTGTGATATGAATTCCTTCTGAAAAGTACCATTTGAAAAGGGAAGGAAAAAAGAGTAACT +TTACAGTAGAGAAACCTGACATGACTTCAGCCACTTAATCAACGTCAATGTCAATAATCC +TAAATGATGTGGAAAGCATACACCTCTGATACTATCTGATAAAATCACTCTGTGCCTCTG +TGACCTTCCTCTCAAAAATCCATAAGCCCAGTCTAACCATGAGAAAAACATCAGACTGAA +CTGGAAGGTTGGACAGAGCTTCCACAGTGTTCTTTTTCATAGTTGGGATGACTTTACATT +TGGAAACCAGATCTAAAGTATTAGTAAGAATCGAAATGCTTGCAAATTAAGAATAATTAA +AATAATTTTATGTTATCTAGATAATTGGTTTGTCTAGTATTCTGAATCTAAAAAATACAG +TCATCTATAGATGGTAATATATTATGATACCTCTATGATCATAATATTTGATTAATATCC +ATTTCCCAGGCCAGGTACAGTGACTCACACCTGTAATCCCAGCACTTTGGGAGGCTGAGG +CAGGCGGATCTCTTGAGATCAGAAGTTTGAGACCAGCCTACCAACATGGTGAAACCCCAT +CTCTACTAAAAATATAAAATTAGCCAGGCATAGTGGCGCACACCTGTAATCCCAGCTACT +CAGGAGGCTGAGGCAGGAGAATCGCTTCAATTCAGGAGCCAGAGGTTGTTAGCCGAGACC +ACGCCACTGCACTCCAGTCTGGGCAACAGAGCGAGACTCTGTCTCAAAATAAATAAATAA +ATTTATCATACATCAGAAATAGGTTTATTATATTTATATGTAAATATATACATTTATATT +TATTATATTTATATGACTTAAGGTTTTGATGACGTGATGATGCTCTAGGGCTGTGATTCT +CAATGGGGAATGAATAAAATTTAACCAAAACTTTTTGGCTGAGGAGAAAATACAAACAAT +TATGGCAGGTAACTAGGTTAACCTGTGGATGGCAAAACATGACTACGAAAGAAAAGAACA +TTTAGAAAGCCTTGGGGAGGGAGGAGGATCGAAAAATAAAATTTAATTTAAAAAGAAAGA +AAGAAAGGCAATAAAGTGTGTAAAATAACTCCAAGAGATCTTTCTTCACAATGCCCATTT +CTGTATCTGTACAAAATTCCCTATGCCACTATGTCAGACAATCTCTTTAGCACTCAGCAC +TCAAAATGCTAGAGCAAGATGAACTAAATTCAAAGACCCTTTTGACACGGAGTCCATCCA +TTTATTTCAGAGATCCCACTCAAGCAAGTGAGGCAGTAGAGAAGAATAAAGAAGCAATTT +AGTGCAGTGTTTAGTAAGAGTACATGTTTGACACTTAACATGCCTGGGTTGATTTGCAGC +TTTGCCTTTTATTACCCATGCAACATCAGGAAAGTTTCATTTATTTATTTATTTATTTAT +TTATTTTTTGAGACACAGGCTTGCTCTGTGGTCCAGACTAGAGTGCAGTAGTGCAATCAA +AGCTCACTGCAGCCTCAACTTCATGGGCTCAAGCGATCTTCCCACCTCAGCCTCCTGAGT +GCTGGCACTACAGATGTATGCCACCATGCCCAGCTAGTTTTTTGGGGTTTTGTTTTGTTT +TTTTTTTGGAGAGACAGGGTCTTGCTATGTTGCCCTGGCTGGTCTCAAGCTCCTGGGCTC +AAGTGATCCTCCCGCCTTAGCCTCCCAAATTGCTGGGATTACAGATGTGAGCCACTGCAG +GTGGCCAGGCAAGCTTCTTAACCCCTCTGTTCCTTAGTTTCTTCACCTGTAAAATGGTTC +CAACTTTAGAGGGATGCTGTGAGGATGAAATGAGATAATCTAGGTAAAATTCTTAGTATA +GTACCTGATACAGAGTAATGTTTGCTATCATTATTATTATTACATATTTCAAAAATCCCT +CACTATCAAACTGTTTGGTCTTTGTTATGTACACAATTCATAAAAGGCAAATCTGTGGCC +CACCAACCTTTCAGAGTTCCATAGTACCTCAAATCAGATGACAAAGATAGGCTTGGACAC +AGAGCCCACAACTCAGAAAAGTCTGTACCCCAAAAGTTCACCTTTTAGTCAGTGGAACAC +ATTTCCCTAAGTGCACAATTGAAACAAGCAGTGGCTGTTATTCCCACTGCAGATGAAAGG +TGTGAGTAGGTGGGTCTGAGCATCTCACTGTGACCAGTACCACTGCTCTGCTGGGGAAGG +TATCTGTGGTACCTGGAAAGAAAAGAACACCGTGACCCTGGAAAAAAGACATCTTCCCCT +GCCATTGCAGCAGCTTGAAAATACATCTTATTCTCAAGGACTTCAAGAACCTAGTCTGTA +CTGTACAAAGAACATCATAGCACTTGCTGTGTCAACATTAAGAAACACTGTAATCCACAA +TACACACAAAGATTATAAAATAAAAAAGTACGGATTTGTTTCTATTTCAAACTCTGACTA +TGCTTTGGGTAATGACCTTTCAAAAGCAGGACACTTTCTAATTGACACTGTCAGAGACCA +GGAAGTGCCCCCCAAAATATGCCTCTTTAGCTAAGGATTTTTTTTGAGCTAAAGGCAATT +AAGCAGCAGCAGATGGAGGAAAGCTCTCGGCCCTCCGTTTGCCTAAAATCAGGACATATA +ATAGATTTACAAAGAGAAAAGGTATCCTGCCCACCTCTCTCCCAAGGAAAACAAAGGTTA +ATCACTGAAGACAACTTTAGACCCCTATCAGTCTGGAGACAGCACAAGAGAATCCACATT +AACGAGCTTTACTAACTAGCCTTAGTATTCAGTTTCCCACAAGTTGTCACCCTGAGAGAT +TTAGAGTTCATTTCCTTTGTCTTGTCACTTCTCTAAAATTTTACTGTTCTTTGTTGAGGA +TGCTACCTAATCTGGGGGAGTGAGGAGAATGAGAGAGAAAGGGGAAGAGGAGAGAGGGGA +GAGAGTGAGGAATTGTTTCAAGGTGAGCAGGTCTATGTGAACCTGCCCCAGAAAGTCCGA +GGAAACTGAGAGGCTGAAGAAAGAGGCTGACATATTCAGTTTCTTAGAAAGACATATTTA +ATAGGAACTTACAAACAGAAGCCATGTCTGTGTCTCAGGCTTTGGCAGGACAAGACAAGG +GATCCACGCACCACTACCCCCCAGACCCAGGGCTTATATCATAGGGAAAGGGTGATCTGA +AGGGATGTGTAGGGCAAGCAAAGTACAATAACATCAAGGTTGCTTGACCTAAGGTCAGGA +TTTATAGTAAGTACCTGTTCTTACATAGGGAATAGTAGATAACCTGGAAATCTTAGAGGT +ATCTTGAAACTGGGGCTAATGAGAAGTCAATATGGCAGATCAGTATCCAAGATGGAGTTG +CTTTGGCCTCCGCAGGAATAAAACAAACATAGCAAAATGTTAACACAAGGAATCTGTGTG +AAGAACATCCAGGAATTCTTTGTCTTGTTCTTGCAACTTGTCTATGAGTTTGAAATCATG +TCAAAGTAAAAAAATTACATTGGATATAAAGCAATACCTTTGTCAAAAGCAATGGAACTA +TACAAGAAATCTGCAGATTGCACCATATGTAAATAACACTTCAATTAAAGTAATGAAACC +TTATTTTAGATGTTTTCTCAAAGTTCGATGATTGGAACACTTCAATAATTAAAAATGGAG +AAGAGAAACCCATTGAGGACATAACAGAATGAAGACTAACTTCATGCATACTTCTAGTTT +GAAACAATCAACTAGCACCGCCGTTTCTGTGTCTGTGACCACAATTATCAGCAGCTCTCA +TGACTTCCTGCTGTACAGCCTCCGCTCCCCTCCCACCACACTTCCCCATGTGACCACCCC +ACACCCTCTGTGCTCAGCTGGGTACCACAATCAGCTACACTACACCCGCTTGCTAATCAA +CCTCCAAATACATAACCCCATTAACAACAAACCTAGATATTACTTTTAATTAAAAAAAAA +AAAAAAGAAGCCAAAAATGACGGTCACAATCCCTCATGAGGACACAGACTATTCAGTGAG +AATCCTTGAGGGAGGCCCTCTGCAGATGCCAGGGCCCAGAACCGGGGCTCGCCCAGCACC +TGGCTTGGAACCCAGGTTAATCTTTCAAAGTACTTTAGGATTTGTTAAAGATTATTATTA +ATGTCATAGTCAGCTATTTTTAAAAACTACTAGTAAAACAAAATGGCTTTCACATCTCAT +ACCTTGCTTTAGAAATACGATAAATTCCTTTACAGTTTGGTCCAAATTCACTCCGTGATA +CACTACAGGTTTGAAATTGCGATGTTCAAAGGAACGGATGAGGCGAACTGTGATGGTCAC +TTCTCCAGGAGCCATGTGAAGAAATTCCTGTGGCAAGAGACATGAGAACCATCTAAATGA +AGCCAGCTCACAGTTGTCTACCAGCACCTAGCCTGCATCTCTATCAGCTCTCTGGCACCA +GCCCCGCTCTTCCATGCTGCATGATCACTGACAGAGTTCCCAAACAGAAGCCAGGTTCCA +GAGTCCCCAGAAGGGTCCCAGTGATTATACCCACCTATCCACTGCAATCCTGGACAGCTC +TGTCACAGTCACAGATGTTCTGACCAGCAGAAAACTGACAGAGTACAGAAGATGAACCAA +AGTAACACAGGGGCATGTGTACGTGTGGAAACAGAGAAGCAGGACGGCCGAACACAAACA +CACAGCAGACACACGCCTATTGTGGGTGCCCTATGTCCGTGGGCCCCTCAGCTGGCCCTG +AGATGGAAGCACATTTACATTAGAATCAACTATCAACAGACAGCATTTCAATTTCATAAA +TGCTGCCAGATTTCAGGGCTTATTTAATTATATACGATGGTGTTACCGTCTTTCACATTA +CTAAAGCTGAGTATGTATAGTTCATCCTAAAACTAAGTACTAGGCACATGTACCAGGTCT +TAATGTTATCTCATTTAATTCATTTAATTCTCTAAACAAAACATGAAGCATTTTGCCTCA +TGGTTTCGTGAGAGAATTAAATGAGATAACATTTTAAAGATGAGAAGACTGACTTGGAGA +GATTGCATAAACTGCCCAAAATCATGAAGCTGGTAAATGATGGAGTCAGGATTCAAGCAT +CAATTTAATTGCAAAGTTCATGCTTTCTAATACACACACACACACACACACACACACACA +CACACACACACACACACAAATTGGAAAACCACCCCAAATTATTTCCTCCAAAAAATGTCT +GCACAGTTGCCAATGTTTTTTTCATGCTTAAAAAATATTTTTGTTTTGAAATATTGTAAG +CAAACAGTTAAAAAAAAAAAAAGAACTTGCTACACTACCCTGTCAAATCTTAACATTCTG +ATGCATTCTGAGTCTTTTAGGAAGAAAACACATCAGAAGCCCCATGTACCCTCCCCAATT +CCATCAGCATTTTCTGCCCTGGGACGACAGAGCAGTGACTCGCACACACCATTCCAATAC +ATAATTTTACACTCTAATTCATATCATTTGAATCTACAGAAAATAGACTATTATGCACAG +CAGTAACAACACTTTCTATATTTTTTTTAATCTTGTTTTGTTTTGTTTGAGACAGGGTCT +CACTCTGTCACCCAGGCTGGTCTCCAACTCCTGGGCTCAAGTGATCCTCCTGCCTTGGCC +TCCGGAAGTGCTAGAATTATAGGTGTGAGCCACCATGCCCAGCAACACTTTCTGTTATAT +ATCAGCAATGCTTACATGCCAGATACTACTCTAAGTGCTTAGCATTCATTAGATCATCGA +CTGCCCACTCACCTCCAATCACCCTGTGAGGTTGGTAAGATCATCTCATACAGAAAAAGT +GAAACACAAATAGGCTGAAGTACTGTGCCCACAGATACACAGTATGGTTAACTTTACATA +CATGGTGTATTATAGGTAGCTTCCACAAGCCTTTCAGCATCGCTTTTCATTTATCTATGT +TGAAAGATGTAACTCTAACTCTCACATTCACTTTCTGAAGTATCAAAAACGCATTTGTTT +TAAAGATACGAGCAGGGCATAGTTCTATCTAGTAGCACCTACTTTGTGCTACTTACAACT +TTGCATGTAACTTTAAACCATAATATACAATAAAAGTAAGTACTAGAAAAAAAATACCTG +TAATACTGATAAATGTAAGGAAAGATATACAATATCACTAGTAGTCAGGGAAATTCAAAA +TAACAGTGAGACATATCACTCATCTAACTGATAAATTACAAAGTCTAACAATACCTACTA +TTGGCAAGGGTAGAGAACAATGAAAACCTCATCAGTGACGGCAGGGACTTAAAGGAGCAG +TACTTTTGGAGACAATAAGGCGATCTTTAGTAAAACTGAAGATACATATACCTTTTGATC +CTACAATTTCATTCATACATAGGTACCCTAAGGAATCTCACATATATATACAAGGAGGAA +CCATAAAATAACATTAATAGCAGTGTAATTTTTTAACTGCAAAAACTGGAAACAACTGTC +CATCAACAGCAGAATTGATAAGTAAAGGATGGTGTACTCCTACGATAGAATATGACAAGC +AATAGAAATGAATGGATTGAAGTACAAGCATTAAACATGGATAAATCTCAAAAATACTAC +CACGAGTGGAAAAAAGCAAGTTGCAGAAGAATCAGAGCATCCTGTACTATCATTTATACA +AAGTTCATAAACATAGTCTTTATTTCGTTTGATAGGAGACAATTGGCCAGGCGCGGTGGC +TCACCCCTGTAATACCTGCACTTTGGGAGGCCGAGGCGGAAGGATCATTTGAGGTCAGGA +GTTCGAGACCATCCTGGCCAACGTGGTGAAACCCAGCCTCTAATAAAAATAAAAAAAATT +AGCCAGGCATGGTGGCGGGTTCCTGAAATCCCAGCTACTCTGGAGGCTGAGGCAGGAGTA +TCACTTGAACCCAGGAGACGGAGGTTGCAGTGAGCAGAGATCGTGCCACTGCACTCCAGC +CTGGGTGCCAGAGCAAGACTCGGTCTCAAAAAACAAAAAAGAAAAAAAAAAAGAAAGGAG +ACAATTATCTGAGGTGTAGGAAGAATTATGTACTTGGGAAGGAATAAATTGGGGCTTCAA +TTATATTAGTAACATTTTATATCTTAAGCAGATGTTAGGTATATGGGTTGTTTGTTTGTT +TGTTTGTTTGTTTTTGAGATGGAGTCTCACTCTGTCGCCAGGCTGGAGTGCGGTGGTGCC +ATCTTGGCTCACTGCAACGTCCCTCTCCCGGGTTCAAGCAACTCTCCTGCCTCAGCCTCG +TCAGCCTCGTGAGTAGCTGGGACTACAGGTACGCGCCACCAGGCCCGGCTAATTTTTGTA +TTTTTAGTAGAGATGGGGTTTCACCATGTTGGCCAGGCTGGTCTTGAACTCATGACCTCG +GGTGAACCGCCTGGCTCGGCCTCCCAAAGTATATCATTCTTTATGCCTTTTAGTATGTCT +GGAATATTTTATAACATACACAAGCAAGTCACATTAATTTGGCCTAGAAAGTCTCTCTGA +ATCTTATAAGCATGTTTTGTGGTTAATGAGTTTAACAAATCTTTTCACAATTTCAATATT +AGTTACTTCACTATTTCTTATTAAATCTGGCTTACAATGCTTCTCAGAAAATCGTATCCC +AGAATCTACCACATAATAGCAGTTCAGCAAATACCTACAAAATTAAAATTTAAAATATAC +TGAAGTATTCAATAAGGAGTAGCTCTTCAGAAAGAGACATATAGAAGCCTCTTGTATTTT +AGAAGCAGTGTTGACAGGTTTGCTAAAGCTATGACCACGTCTCCCTCTTCTCACCCCCTA +AAACAACAAAAAAGCCCTCCCATACACACGCATATGCACACACCTATACCTACACACACA +CACACACACACACACACACACACACACACACTGGGAAGCGCTGGAATGCAGCCCAGTGTC +CCTAAGAACCTAGAGTTGAACAGATTTAACTTAAAGATCAACTCTGCTTCTTAGCTGCAA +CTGTCTGATATATAAATAAGAATTCCTTAAAAAGCTGTTCCATGTTAGCCGGGCGTGGTG +GCACATGCCTGTAGTCCCAGCTACTCGGGAGACTGAGGCAGGGAGGTGGAGGTTGCAGTG +AGCTGAGATTGCGCCACTGCACTCCAGCCTGGGCAACAGAGTGAGACTCCATCTCAAAAA +ACAAACAAACAAAAAAACAAGTCGTTCCATTAATTTAAGAAATTAACATACATAAAACAC +AATTCCTCACACACAGGATCTCAATAAGTAGTAGCTGCTTTTGTCATTATTATTCTATTT +GGATTAAAATAGGTTTGGGTATAAAGACAGCCTATATAAGCAGCAGATAAAGATAAATTC +CCAGATGTAATGAAGCGAAGGCTGGGCAGGCTGGCACTTGCATTCCTCATGAAACTGTTT +TTCACAATTACAGGTTTGTTATTTTCACTTAATAAAAAGCTGCCCATATGCTGTACTTAA +ATAGTTGAACTTTTCCATTTAAAACCCCAAAATTTGTGTTATATCTAATTTTGGACAACT +ATTGTCATCTTTCTTTTATGTGCTTCAATTTATACTCAGTAACAAAACAATAGCTACTAT +CAGAAGGACCATTATCTAATTTGCCTTAAGGACAGTGGGACATAGGCTTGTTTGCCTAGA +GGAGCTGCCTCAGCTTAGAAGACTAACCTTACAGATAATAAAATCTGACATTTTTCCCAG +AAAGTTTGGCCTAGTTTTTTAAAAAAGTGAATCTGATCAATTTTTAAAAGTATTCCTCAA +ATGAAAAGGCAGAGAAGCCAATAAAAATAAACTTCAGGATAAATTAATTAAAAATATTCA +AGGATATAAAAGATTTAAATAAATGAAATGATAGACAATGTCCTTAACTACAAAGGTTCA +AAGTAGTAAAGAAATCAAGTCTCCCTAAATTGACCCATTGAATAAAATCCCAATCAAAAT +AAAAAAGAGCTGTTTGGGAATCTTGACACAAACAATTCTAAAATCCATCTAGAAGAATCT +GTGAGCTTTGTCAGCAAAGTCATAAAACAACAAAAAAGAAAAGAGACCAGTGACACCAAT +TATTAAAACACATTATAAAGCAACTGTTACATAGGAAAAAGCTTGTTTGATTTTCATAAT +TTTACAAAATCCAATAACAACTATTTTAAATGCAAAATCAAGCCACGGTAATATAAAATC +GGATACTGGAGCAGAAATAGATGGACAAATCTGTGAAATCTAACAGAGAAGTCAGACTTA +AGATTATAGAAAATTTAATATAAGATGAAAGTGGCATCTCAAATTAGTGGGGAAAAGATA +GTTTCCTTAATAAATGGCATTGAGAAAACTAATAATGGATTTGGGGAAAAGTAACAATGG +ATTCTTATCTCACTCCTTATACAAAATAACGTGTCTATGAAACAAATATTTAACTATAAA +ATCATGAAGAGGCACCAGAAGAAAATAGGTACATATTTTTATAATCTTAAGATAGGAAAA +GCTCTAAGCAAAGACAAAGCAGCAATCATCAAGGAAAAGACTGATAGTTGTAACAACATA +AAAATGTAAAAAGAGACCAATATCCTAATAGAAACAAGGATAAAGGTAATTAACAGGCAA +CTGGCTAAACTTAAGCCAATAATGTGAAAAGATCAGCTTTACTTCCAACTAAAGAACTGA +AAGAGAAACAGTTATCAATTTTGCCATCAGACTGGTATAATAAGAAAAATTGAAAACTGG +CCAACCAGTGTTGGCAAGGATATGGAGAAACAAATATTTTTTTATAAACAACTGGCAAGA +ACATAAAATGAAACAGCCTATCTGGAGGTGAGTGGGTAATCTGTACCAAAATTTTAAATT +TGTCTACCCTTTGATATGGCAATTTCTTTTCTAACAATTCACCCTGAGAAGAGAATCATA +TCAATTATTTTATAAACCCATGGGTTCATAATGACACTTTTTTAAAAAGCTGGTCATTCT +GGAGGCTAACAAGGCACTAATTTGTTTTTCTGAAAAGTGGCTTTCCAAGTGAGGGTTGGT +AGAAATAAGAAGTCAAACATTTTACCCTTCCTTTCTTGTACAGACAGTATTTCAGCGTTA +TCAAATAGCTGATGAAAAAAAGTTTCTTCTTTATAGAAGAATTACAGCTAAAAAGTACTA +AAAGAATAAAATTTTGGCCAGGTGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAG +GCCGAGGCCCGCGGATCACAAGGTCAGGAGATTGAGACCATCCTGGCTAACACGGTGAAA +CCCCGTCTCTACTAAAAATACAAAAAATTAGCCGGGCATGGTGGCGGGCGCCTGTAGCTA +CTCAGGAGACTGAGGCAGGAGAATGGCGTGAACCTGGGAGGCAGAGCTTGCAGTGAGCAG +AGATCGTGCCACTGCACTCCAGCCTGGGCGACAGAGTGAGACGCCATCTCAAAAAAAAAA +AAAAAAAAAAAAGAATAAAATTTTAAAATCCTAATTTACATACCTATCAGGATGGCTAAA +ATAAAACACAGCAATAGCCCCAAATGTTGGTGAGGGTGGAGAAATTCACATACATTGCTG +GTAGGAATGTAAAATGGTACTAGCCAGTCTGAAAAAGAATATGGCAATTTCTCACAAAAC +TAAACATACCCATTATATAACCCAGTAATTGCATTCTTGGGCATTCATGCTAGAGAAACA +AAAAGTTATGTTAACACAAAAACCTGTATATGAGTGTGCACAGCATATCCATGTGTAATG +CCCCAAAACTGGGAAATAATCCAAATGCCCTTTAACATATGAATGGTCAGGCAAACTGCA +GTATATCCATATCATGAAATACTAGTCAGTAATAAAAATAAATAAATTATTGATACAGGC +AACAATCAGGGTGAATCTCAAGGGAATCAAGCTGAATGAAAAAAGGCAGTCTCAAAAGCT +TGCATACTGTATAATTCCATTTTTATGTCATTCTTATGATGACAAAATTACAGAAATGAA +GAATGCATTAGGGTGTTGCCAGGGGTTAGGGGAAGAGGGGGAAAGAGGTGTCATGTCTGT +GGCTATTAAAGGGTAAAATGAGAGATCCTTGTGATGGAAATGTTCTGATTCTTGACTGTA +GTGTTACCCATTTTTATCTACATGTGATATAACTGCACAGAACTAAATGCATACACACAC +AGGCATACACATATATACACACACAAGTGTATATAAAACTAGTGAAATCTAAATGAGGTT +CATTGCTTGTATCAATTTCAATTTCCCGGCTGTAAAATTGGACTATACTCAAGCAAGGTG +TTGCCAATGGGGGAAAGTGGATGAAGGGAAATGGGATCTCTGTATTATTTCCTACATCTA +CATGTGAATCTACAATTATCCCAAAATAAAAAAATTCCAAAAATTATCATTCTGAAAACT +CTAATGAAATGAGTGTAGGTGATGATCATAAAGCGGTGTTAAAACCATCAGGTAAGACTG +ACGGGGAACTTCAGCATGGGTACATCTGGGGCTGACAACACCTGAACTTCATAATCAACA +TTAGTGAATGAATCGAGCCTCCAGATCTCATTCCCAGTTTATCAGCTATGACAGGGTATG +GAAGAACATGTTAAATGACACCACAAGGAGGCCATCAGCCAAGTTCAGATGGTGGAAAAT +TGTACTGGAAAAATGACTCGATTTCTTCAACAAATGGCATGAGAAATAAAGAAAAGAGAG +GAAGGCTATATATTAAAAGAGACTTAAAAGAGCTAATCTCAACGGATGCAACATTTAGTC +TTTGTATGGATCCTAATTTGTATAATATTAGATGATATTAGGAATTAATGTTAATTCTGT +TTATATGATATTATGGTTGTGTTTTTAAGTCCTTATCTTAAAAGACTGAGGAATATACAG +GTGAAATGATGACCTGTATTTGCTTTCAAATACCCTAGCAGAGGAAAAACAATTATAGAA +GCGTAGATTAAAAAAAGAATAGTAGAGACCAAGCATGGTGGCCCACGCCTGTAATCCCAG +CACTTAGGAGGCCGAGGCAGGAGGATCACTTAAGCGCAGGAGTTCAAGACCAGCCTGGGC +AACATATCGAGACCTCATCTCTCCAAAAATAATTTTTTAATTAGCTGAGTGCAATGACCT +CAGCTAATTAACCTTTTTATCTTGAAATAATTGTAGATTCACATGTAGATTTGGGAAATA +ATACAGCGCTCCCATTTCCCTTCATCCACTTTCCCCCACTTGGCCACATCTTGCTTGAGT +ATAGTCGATTTTACAGCCAGGAAATTGACATTGATACAAGCAATGGACATCTATAATCCT +AGCTACTTGGGAGGCTGAGGCAGAAAGATCACTTGAGCCAGAAGTTTGAGGCTGCAGTGA +GCTATGTACTGTGCTCCACACCACTACTCTCCAGCCTGGGAAACAGGACAAGGCTCTGTC +TCAAAAAAAAAAAAAAAAAAAAAAAATACTAGACCATTGTTAACTGTTGAAGTTGGTTAT +GTATGAAATCTCATATACTATTCCATTTGTAAATGCTTGACATTTTTCATAATAAAAACA +TTTTGCAAGAAGACTATAAGTGCGCAAAGGTGTACATTCAAAGATTTTCTTTCACTGAAA +TGTTTCTAACAGTTAACAAAATTAGAATCCACTTAAATGTCCAACAGTAAAGAAATGGTT +AAGTAAATTATGCCACACAGTAAAACAAAATACCCTGCAGCCATTAAAGGGTGATATGGA +TGTATGGATACCAACTTTGAAAGATGGCCATGACATACCAGTGAGTAAAAAAACAACTTA +GGCTGGGCACAGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGTCAAGGCGGGTGGA +TCACCTGAGGTTAGGAGTTAGAGACCAGCCTGACCAACATGGTGAAACCCTGTCTCTACT +AAAAGTACAAAATTAGCCAGGCGTGGTGGTGCGCGCCTGTAATCCCAGCTACTCGGGAGG +CTGAGGAAGGAGATTCGCTTGAACCGGGGAGGCAGAGGTTGCAGTAAGCCAAGATTGTGC +CACTGTACTCCAGCCTGGAAGACAAGAGTGGAACTCTGTCTTAAAAAAAAAAAGAAAAGA +AGTTAAAGGGCTCGGTGCCGTGGCTCACACTTGTAATGCCAGCACTTTGGAAGCCCAAGG +TGGGCAGGTTGTTTGAGTCCAGGAGTTCAACAGACCAGCCTGGGCAACATGGTGAAACCC +CATCTCTACTAAAAATACAAAAGTTAGCCCGGCATGGTGGCGTAAGCCTGTAGTTGCGGG +GCTGAGGTGGGAGGATCGCTTCAGCCTGGGAGGCAGAGGTTGCCAAGAGCCAAGATTGCA +CCACTGCACTCCAGCCTGGGAGACAAAGCCAGACCCTGGTCTCAAAAAAACAAAACAAAA +CAAAAATTAGAAAATTGCCTGTGTACAGTATCACTGCATGTTTGTAATGTAGGTGTGTTA +CATGTGAACATAAGCATGGAGAGATGTCCAGAAAAGCCTTTACCAAAACATTAACAGTGG +CTGTCTCTGAGGGGCAGAAATCCAAGAGACTGTTACTTGTTTTATATACTTTTTAATATT +GTTTGATGTTTTACCAATCATGTGTTTTTAAATTAAGCTATTTCCAGTATACTTGTATTT +TCACTTTTCTGATATATGTGTATGCATCAACAATAAGTTATTTTTAAAACTCAGCTATTT +CCATTTGTTTTTAAGAAGGAAGAGACAACAGAACAAAGCAAACAATACCAAACTTACAGA +GTACTGGAAAGGAGGGAAAGGCTAGGAACTTAGTTATACTCCTGCTATGTACCAAGGAAC +ACCAAATAAATCCAAACAGCATTCGGAGGCACCAGAAGCAGGTCACACGCCCAGAGGAGT +CTGAACTTGTCCCGCTGCCTCTTCAGTGGTATACGTCAACATCAAAATCTGCTTTTAACA +TATCCCTCCAGCTACAATGACAGCTCACAGTTCCCCACACCCACCACGCTGTTGCCAAGC +CTCTACCACACCTCTCCAGCCCCAGCTTCTCTCCAAAATCCCTCCGCCCCTCACCCTCTT +TGCTTTCCCACAGAGGCTCCTTCAAGACCCAGCTCAGGGGGCTATCTTCTGCAGGACACC +TTTGAGCTGGGCTCCTCCTCTCCCCCAGGCTGAGCCATGGGCCCCCTCTGTATGCTGTAG +CACCTATCACTCGATGTCGATGTCATCTGTTTTAGAGGTCTGGCCCACAAGCTCTTTAAA +GGGAAAGAATGCTGTATGGTCCGTTTTTGTAGACCCAACAGCTTGTGTAGCGTGAGGCAC +CTCAGAAGCCCCATAAATGTTCTTTTTAAAATTGTTAATTTTGTGTAGAGCTAGGGTCTA +TGTTGTCCAGGTGGGTATTGAACTCCTGGGCTCAAGCAATCCTCCTGCATTAGCTTCCCA +AAGCACAGGATTACAGGTGTGAGCCACCACGCCCCGCCCACACCGCCCCCCGCCCCCCCA +CCGTCCCGCGTAAGTGTTTGTAGAACTAATGAGCAGTTAAAGGGAGGAAAAAAAACCTGA +TTTCTTCCATTTCCTAAGGACACACGAACATGGCAATCTTGCACTAGAGACACAGGACCC +AAGAAAATGTTTGAGATGTGGAAAAAAAATCAAAATTAATATTAATTATATATTTATAAT +ATGTAACAGTTCAACAGCAACTTGATTCTATTCATAATTATATATGTTAGATTTAATGTA +GGATACGTGTATATTTCAACACATAAGACCCAGGTGGTGCTTTGAAAAGTAAGAGTGCCT +AGGGCTTGGGAAGGTCTTTAAGCCTCCCTGCCTAAAAAACCTGTAGTTCTAGCTAGTAAC +TTACCCAGCTAGTTTGGGGCAATGCAGAAAAGCCCATATGCAAAGCAAAACAAAGCTCTT +ACAAACAAAGCAAACACAAAACTTCCATAGGAACTGCCTTGCATGGAAGTCCCAGTTCGA +TGGCCAGTAACCACTGCATCAGAGCAGCCCAGCACCCTCCCCTCTGCAGCTGCTTTTTTG +GTCCAAGCTGCAAGGATGGTGAGGAGGGAAGCATAGCTTGGAAGCTTTGAGACCCCATAG +ATGAGATGGGCCTTCAGCCTTCAGTCCTGGAGCCTGTGGTGGAAATTCAGCAACCAGGCA +AAGCCAGAACAAGCTAACTGCAACGCTCCTTAACTTGCCCAGTGGTTCCCCTTCCCAAGC +TGGCTGGTCTCCCCAGGGCAGAGCTCTAAGCTGCAGAGTTATAAACCAGCAGGGGCAGGC +TTCTGGATGAAAAACTAGGCACCACACATAAAAGCTCAGAGCCGAGCATCCAGATAAGCA +CAAAACACCCACAAGATACTTGATTGTTGATGTTACACTGATCTCTGTCAGCTCAAAAAA +AAACATCACTACAGTTGATTCTGGTTGTTGGTAGTAGTTATGGTTTATAAAGTTGGCTGT +GAACACTGAATTAGCAAATCCTGAACCACTGCTCCTAGGGGAACTACAGGATTAGGGTCT +CGTGAGCTCGACTTCACATTTTGGCAAATGATCAATACATAATCTTGTTTCATGCATGTT +TCTGTTGAAAGAGACATTTATTATGTGTTGCTAATTCATCAGCATTGAACTCACAGCCAA +CACCACTCACAGCCTGCCTGAACAAAGCTTATCTAACACAATATTTAATATTTTCTCCAT +AAGGCACATCACAGCCTTCCTGCGCCTAGGAACACTTGACTGCACGTCTGCGCTATGCTT +GGGGGACATTTTAAATAGCAGAATCACCAACAGAAAAGCATTAAAATGAAAAAAACATGG +CAATAAATAGTCCACAAACTGGTCACTTGTTTACAATATAAGAGCTGAAACAAGAAGGCA +GAGCGACTGGGCACGGTGGCTCACACCTGTAATACCAGCACTTTTGGAGGCCCAGGCGGG +AGGATCACTTGAGCCCAGGAGTTTGAGATCAGCCTGGGCAACATAGCAAGACTCTGTCTC +TACAAAAAAAAATACCAAAATTAGCTGGGTGTGGTAATGTGTGCCTGTAATCCCAGCTAC +TCAGGAGGCTGAGGTAGGAGGATCCCCTGAGCCTGGGAGGCAGAGGTTGCAGTGAGCCAA +GATTGCACCACTATACTCCAGCCCCAGCCTGGGCAACAGAGCGAGATCCTGTCTCAAAAA +AAAAAAAGCATAGTGTTGTCTTGTTTGACTTCAGCTGGGAATGTATTGAGTGACTCAAAA +TTTTCACTGCTCTGCACATGTCCAAGAATGACCAAGAAAGTGCCATGAATATTGCTTTTG +GGGTTACAAATAAATGTTAGTATGTAGGTGAATTTGCAAATACAGAATCTGAAAATAATT +AGGATTGACTGTACTACCTAAAAAACCTGGTATATATGCCTTATGGTATTCGAAGAAAGC +ATCTTCTTGACTTTTTTGTAAGAGAATGGAATCCAAAATGAGCTATTAGAAGCTTTAAGG +GTAGGAAAAGCACTCAGGCACTAAGGCAGTTAACATGGAGAAGACCCTATAACCACTTGC +GCACTGACTGACCTTCCGTCATGCCACACGCAGGTTTCCAAGAAATTATGCTTATGACCA +GAATTTTAACAAACTCCTAGAGAGAATCATTTTGAAAAACCAAAATATTTTATAAAGCAT +ATATACTCCCTAAATTTAAGTACTGTAAAATTACACTTGTCATATATCAACTTTGCTTTA +AAGTTTGTCTTATCCAAATGAAAAAGGTACAACTTTCAAAAAGGGAAGGTTCTAACCACT +GTTCAATTAAATTTGGCCTAAAGCTGCCTCCACAGGTAATGAACTGCACCCTATCTTACT +ATGTAAACAAGCTGCAACCTAACCTGCAAGTGTATTCTTGGAATAAGTAACTGAGTCTCA +GCCAATCACAGCAGCCAAACTTTCAGCCAATACAGGCTGCAAACTGCCAAAACATGTCAA +AATAAGGCAAAAGCCAAGCTGTAGCCAGTCAGACTATTTCAGTCTCTCACTTCTGTTTTC +TGTCTATAAATACCACCTGCTGGGTATTTATAGACAGAAAATACTGTTGCTGGTTAGAGC +TCTCTGAACCTTTACTGGTTCAGATGCTGCCTAATTCATGCATTGTTTCTTTACTCAAAT +AAATGCTGCTAAATTGAATTTGTCAAAAGTTTTCCTTTTAACACCAGATTCTCTCTCTCA +TTATAGACAGGTTATATATATAGAGAGAGTGTATTAGAGTGATTACATATACATACCTAC +GTATGTATGTATATGTAATCATGCTAAATGCTTAATTCTCCTCAAGATTTAGGAACCAGT +ATCACAGGGCAGAGAGTCCATCACCTTCCTTTTAAAACAAATAAATCAATAAAAAGAATA +TATGAAATACAGTTGTTACTGTTCTTTTCTGTGAGGAAACTAAATTGGCAAAGGTGAGCA +GATATAAAAGGAGAAAGAGCAGGAAATTGTTAAGAAGAAAATCACTGAATATGCAAATGA +TTCTGAAACTGCCCTTAATGATTTTGGAGTAAATAATCCTTAAGTACAATTAAATAGCAT +TCAAATATGTCATTTTATCAAAAAAAAAATGTTGTTTAAGGCCAGGGGTGATGTGGGGGA +GCCTAAATTATTTTTATTATCCTTCTTAAAAAGATGGAACACCTAGCATACTGTTAGTAG +ATGAATGATAAATGCTCACCATTTACAGAAAATTTAACCTTGGCAAATTAATAACTTTAT +ATTAATTTCAGTTTAAGTTTAGAAGAATGACAAATTAAAATTAATTCACACTTAGGACTA +TGACTAAAAGTAAAATGTTAATTGCATTTTAATCTACTCTGGCCTACTTCAAAAGCATAA +TTTTAACTCTTGGATGGAGAACGAAATTTTCTTCTAAAAATAGATTTCGGTAACAATGAA +ATATCAAGAGCTGGACATTATAATAAAAAGAAAAAAGGTAACAAGAATTTTCTTTTTTTT +TTTTTTTTTTGAGAGTCTCGCTGGAGTCTTGCTCTGTCACCCAGGCTGGAGTGCAGTGAT +GCGATCTCAGCTCACTGCAACCTCTGCCTCCCATGTTCAAGTGATTCTCCTGCGCAGCCT +CCAGAGTAGCTGGGACTACGGGCACACGCTGCCACGCCTGGCTAATTTTTGTAGTTTTAG +TAGAGATGGGGTTTCACCATGTTGAGCAGGCTAGTCTCGAACTCCTGATCTTAGGTGATC +CGCCCGCCTCAACCTTCCAAAGTGCTGGGATTACAGCTGTGAGCCACCACGCCCAGCCCC +AAGAATTTTCTTTTTAGGACAGACTGGAGAAAGGGTGGGAAAAGGATTGGGAGAGGCTGG +TTGAAGGTACAGTTGAAATTAAATAGGAGGAATCAGTTCTGGCGTTCTATGGTTAACAGT +ACATTACAAAATAGCTAGAAGAGAGATTTTTAAATATCCTCACCACAAAGAGATAAATGC +ATGAGGCAATGGTCACACTAAATACCCTGATTTGCTCATTCTACAACTTATATATGTATT +GAAACATCAAATTGTGCTCCCCAAATATGTACAATTACGTGTCAATTAAAGAATCTGCTT +TAAATTTTTTCAAAAGCATATTTTTTTAAAATATGAAACTCAGCATTTATAAACTACATT +AATGGCAGGGCACGGTAGCTCACGCTTGTAATCCCAGCACTTTGAGAGGCTGAGGAAGGC +AGATCACTGACGGATCACTTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACATGGTGAA +ACCCCGTCTCTACTAAAAATACAGAAAAATATTAGCCGGGCGTGGTGGCACGCTCCTGTA +AGCCCAGCTACTGGGAGGTTGAGGCACGAGAATCGCCTGAACCAGGAGGTGGAGGTTGCA +GTGAGACAGGATCGCACCACTGCACTCCAGCCTGGGAGACAGTGTGAGGCTCTGTCTCAA +AATATAAAAATTTTTTTTAAAAAACCCTACATTTATAAACTAGGACTATATGAGGGTTAA +ATAACATTTGAAAACTTCTTGGCATTTTTTTGTTGTTGTTTAGCTGCATAATACAAATGA +AAGCACCATTATTCTAGAAGAGTTGGTTAAATCATCTTTCACTGACAGAACTTTTGAGAA +AGATATTTTCAACATATTCATTTATAAATGATTTCAAAGTCTTCAACCTCAGCCATTTTT +TAGATAGGTCAAAAAAATAAAATCTTCCACCTCTAGGGGTTTAGGTAACACAATAGGTAC +AAGATAAATTTTAGCTAATCTGCTGACTGGCACATGCTTCTCCATGCTGTAACTGCTTTA +CTGCATAATGACATTAGCAGCTGACCTTCCCTGAGGAAGAACCATAATCAGTTCCAAATA +AATATATCCTTGATTACTGTTCACATCTAGAATACACCACCCACTGACAAATCAACATCT +ACAATTCCTCAGACCTGCCATTATGACCTTGAATCTGGAGCAAATACACAAAACCATAAT +TCGTTTTCTCTGCTCAAGATATGCAAGACTCTCCATAAACCATTCTGGACAGTTGAGTTT +TCCCAAGGGTTGGAGACTTAACCATTTAGAAAGAATATTTCATACACTTTCTTAAACAAG +GTATACTGGGTATAAATTCTATTTTTCTTGATTTGCAACCATCAGTGAGAATATTAATCC +TTGTACTGTGTGTTGGGAGACATTTCTCCATGGGTCTCTCACACGTCTGCGTGTCTTAGA +AGCAGAGGGGCTGGCTGCTTTCATTCTGAACTATCTTTCAAGGATATGTACATAGCGAAC +AGCTTAGAAAGACAGAGACAGTATCTCCCACCAGACTGTCCAGTAGCATGAAGACATCTC +ACTCCAGGGTAAGGCTGGGCAGGTTTGCTTGCAGCCCTTTATAAAGAATTTGATTTACCT +AAACCTGGGGTTCTACAGCTGTGACATAAACCCACTGCACATGCAGTAGCAACTGAGCTA +CTCTGATTGCCCCTGTGGGACCTATAGGGAGGAGGAATGGAATAAACTCCTCCTCTCAGT +GGTGGCATTAGATTCTCATAGGAGCGTGAACCCTATTGTGAACTGAGCATATGAGGGATC +TAGGTTGCATGCTCCTTATGAGAATCTAATGCCTGATGATCTCAGATGGGACAGTTTCAA +CCCAAAACCATCCCCCTACCACCCCATCCATGAAAAAACTGTCTTCCATGAAACCGGTCC +CTGGTGCCAAAAAGGTTGAGGACTGCTACTCTACAACACCATCCACCGAACAGGATGTAA +TGGACATTTATAGAACACCCCACTAATGACTGCAAAATACACATACTTTTCAAGTATCCA +CAACATAGATGCCAAGACGTCCACATCCTGCACCACAGGAAAAAACCATGACGAGTCTGA +AGAAGTGAAATTAAACAATGTGTTCTCTGACCACAGTGGAATCAAATTAGAAATCAGAAA +CAGGAACCTACCAGGAAAGTCTTCAAACACTTGGAAACTAAGCAACAGACTACTAAACAA +GCCCTGGACCAAAGACGAAGTCTCAAAGGAAACAAAGGCCAGGTTCGGTGGCTCTCAGTT +GTAATCCCAGCACTTTGGGAGGCTGAGGTGGGCAGATCACTTGAGGTCAGGAGTTCCAGA +CCAGACTAGCCAACATGATGAAACCCCAACTCTACTAAAAATACAAAAATCAGCTGGGCT +TGATGGCAGGCACTGTAATCCCAGCTTCTCAGGAGACTGAAGCAGGAGAATCGCTTGAAC +CCAGGAGGGAGAGGTTGCAGTGAGCTGAGATCACTGTTCTCCAGCCTGGGTGACAGAGCG +AGACTCTGTCTCAAAAAAAAAAAAAAAAGGAAACTAAAAATACACTGAACTGAATGAAAG +TGGGACACAGTTAAAGCACTGTGAAGAGGAAAATGTATAGCACTGTGAAGAGGAAAATGT +ATAGCACTGTGAAGAGGAAAATGTATAAATGCATAAATTAAATGAGAAAAAGTCTCAAGT +CAATAATCTAAGCTCCCACCTCAAGAACCTAGAAAATCAAGAGCAAAACAAACCCAAAGC +AAGCAGAAGGAAAGAAATAATAATGAGTGGAAATCAATACAATTGAAAACAGAAAAACAA +TAGAAAATCCATGAAAAAAGAGGTGGTTTTTTGAAAAGATTTTTTAAACACTGATGAATC +TTGAGCAAGACCAGCTAGGGAAAAAAAAAAGAAGGCACAAATAACCAATATTGGGAATGA +AATGGAGGATATCATTACAGGCTCTGCAAATAGCGAAAGGATAATAAGGGAATACTATGA +ACTAATTACATACATACATTTCACAGCACAGACAAAATGGACCAATTTCTTAAAAAACTA +AAACTACCACCACTCACCAATATGAAATAAACAATATGAATAGCCCTATAACTATTAAGG +AAATTAAATTCATAATTTAAGAACTCCCAAGAAAGAAATCTCTATAAGAACCTGATGAGG +TGCCTGGAAAAAAGGAAGGAAGGAAGGAAGGAGAAAAGAAAAGAAATCTCCAGTCCTAGA +AGGTTTCACTAGAGAACTCTACAAAACATTTAAAGAAGAATTAACATCAATTGTACACAA +CCTCTTTCAGAAAATGGAAAAGGAACATTTCCTAATTCACTTTATGCAGCTAGTTTTTCC +ACAATAAAGCCAGACAAAGCCATTACTAAAAAAAAGACAACAACAGACCAATATCCCTTA +TGAATATAGACATGAAAATCCTTAGTAAGACATTAGCAAATAGAATTTAGCAATACATAA +AAATAATTATACACCCTGACCAAGTGGTTTTTTCCAGAGAAGCAAGGTTAGTTTAATATT +TGAAAAGCAATCAATGTAATCCACCAAATTAACAACCTAAAGAAAAATCACATGATCACA +TCAAGTGATACAGAAAAGGCACCTGACAAACTTCAATGGAGACTCAACATCCACTGACAA +TAAGGACTCTCAGAAAAACAAGAAAAGAGGGGAACATCTCAATTTGATAAAGAGCATCTA +CAAAAAACAAACCAAAAAAAAAAAAAAACTAGAGCTAACGTTAGACTTCATAATGAAAGA +CTGAATGCTTTCCCCCTAAGATCAGGAACAAGGAAAAATAGCCATTCTCACCATTCTTAT +TCAACATGCTGCTGGAAGTTCTAGCCAGTGAAACAATGCAAGACAAGGAAATAAAAGGCA +AAGAGATGAGAAAGGAAGAAATAAAACTGTCCCTATTTGCAGATAACATGATTATCTACA +CAGAAAATCCCAAGAATTCTCAAAAAACAAAAAAATCTGGAATTAATGAATTTGGCAAAG +TCACAGGATACAAAATAAACATACAAAACCAACTATATTTCCAAATAGTAGCAATGAACA +CATGGAACACAATATACAATATAAATACAAATACAAAATACAATAACATTCACAATCACT +CAAAAACAAGTATTTAGGTGTAAATCTAACAAAACATGCACAATAATATTGAAATTAGGC +CAATTAATAACACTGCAATGGCCTCTAAGTTTTTAAGTGACAGGAGGAGTTGTTAGTCTC +TCATTTTAAATCAAAAGTTAGAAATGATTAAGCTTAGTGAGGAAGGCATGTCAAAAGCCA +AGATAGGTTGAATGCTAGGCCCCTTGCACCAAACAGCCAAGTTGTGAATACAAAGGAAAA +GTTATTGAGGAAATTAAAATGCTATTACAGTGAACACACAAATGGTAAGAAGGCAAAACA +GATGGCTCACGCCTGTAATCCCATCATTTTGGGAGGCCTAGGTGGGTGGATCACCTGAGG +TCAGGAGTTCAAGACCAGCCTGACCAACATGGAGGAACCCCTGTCCCTACTAAAAATACA +AAAATTAGCTGGGAGTCGTGGTGTGCATCTGTAATCCCAGCTACTCAGAAGGCTGAGGCA +GGAGAATCACTTGAATCCGGGAGGTGCAGATTGCAGTGAGCCGAAACTGCACCACTGCAC +TCCAGCCTGGGTGACAGAGGGAGACTCTGTCTCAAAAAAAAAAAAAAAAAAAAGGCAAAA +CAGCCTGTCGCTGATATGGAGAAAGTCTGAGTGCTCTGGATAGAAGGCCAGACCACCCAC +AACATTTCCTTAAGCCAAAGCCTAATCCAGAGGAAGGCCCTAACACTCTTCAATTCTATG +AAGGCTAAGAGAGGTGAGAAAGCTATATAAGAAGAGTGAAGCTAGCAGAGGTTGGTTCAT +GATGTTTAAGGAAAGAAGCAGTCTCCATAACAAAAAAAGTGCAAAATGAAGCCTCAGGTG +CTGATGTAGAAGCTGCACCAAGTTATCCTGAAGATCTAGCTAAGATTGATGAAGCTGGCT +ACACTAAACAACAGATTTTCAACACAGACAAAACAGCCTTATATTGGAAGATGAAGCCAT +CTAGGATCTGCATAGCTAGGGAGAAGTCAACGCCTGGTTTTAAAGCTTCAAAGGACAGGC +TGACTGTGGGTAAGGGTTAAGGCAGCTGGTGACTTTCAGTTGAAGCCAACGCTCACTGAT +CATTGTGAAAATCTTAGGGCCCTTAAGAATTATGTTAAATCTACTCTACCTGTGCTGTAT +AAGCGGAACAACAAAGTCTGCATGACAGTGCATCTGTTTACAGCATCGTTTATTAAATAT +TTTAAGCCCACTGTTGAGACCTAATCCTCAGGAAAAAAAAGATTCCTTTCAAAATATTAC +TGCTCATTGACAATGCACCTGGCCACCCGAGTGCTCTCATGGACATGGACAAGGAGATTC +ATGTTTTCATGCCTGCTACCACAATATGCATTCTGAAGCTTATGGATCAAGAAGCAATTT +CAACTTTCATGTCTTATTATTTAAGAAAATACATCTTGTAAGACTACTGCTACCGTAGAT +AGTGATTCCTCAGATGGATATGGGCAAAATAATACGAAAACCTTCTGGAAAGGATTCACC +ATTCTAAAGGCCATTAAAAATATTCATGATTCAGGAGGAGATCAAAATAGCAACATTAAT +AGGACTTTGGAAGGACTCCAACCTTCATGGATGACTTTGAGGAGTTCAAGACTTCAGTGG +AGGAAGTAACAGCAAATGTGGTGGAAATAGCAAGACAACTAGAACTAGAAGTGAAGCCTT +AAGATGGGACTGAACTGCTGCAATCTCATAATAAAATGCCAGCGGATTAGGAGTTACTTC +TTATGAATGAGCAAAGAAAGCAGTTTCTTGAGACAGAATCTACTCCTGGTGAAAATGCTC +TCCCTGTCGCCTAGGCTGGAGTGCTGTGTTGAAACGACAAAAAAAGCGTTTAGAATATTG +CATAAACTTGTAAAGCAGCAGCATGGTTTGAGAGAATTGACTCCAATTTTGAAAGTTCTG +CTATTGATAAAATGCTGTCAAACAGCATCTCATGTTACAGAGAAGTCTTTCTTGAAAGGA +AGAGTCAATCAATACAACAAACATCATTGTTAGCTTATTTTAACAAATTGCTACAGCCAC +CCCAACCTTCAGCAACCACCGCACCAATCAGTTAGCAGCCATCAACATTGAGGCAAGACC +CTCGACCAGCAAAAGGATCATGACTCGTTGAAGTCAGGTGATAGTTAGCATTTTTTAGCA +ATCAAGTATCTTTAATTCAGATATGTACATTTGAGGCCAGGCACGGTGGCTCATGCCTGT +AATCCCAACACTTTGGGAGGCCGAGGCAGGTGATCACCTGAGGTCAGGAGTTTGACCAGC +CTGGCCAACATGGTGAAACCCCGTCTCTACTAAAAATATAAAATTAGCCAGGTGTGGTGG +CACATGCCTGCAATCCCAGCTATTCAGGAGGCTGGGGCAGGAGAATCGCTTGAACCTGGG +AGGCAGAAGTTGCAGTGAGCTGAGACTGCACCATTGCACTCCAGCCTGGGCAACGAGAGC +AAAACTCTGTCTCAAAAAAAAAAAAAAAAAAAAAAAGATATATACACCTGTTTGACATAA +TGCTATTGCACACTTTATAACAGACTATACGTATAGTGTAAACATAACTTGTATATGCAC +TGGAAAACCAAAAAACTGTGACTCATTTTGCTGTGATCATCATTTTATGTCAGTGGTCTG +TGACCAAACCTGCAATATCTCTGAGGTATGCCTGTAGACAAGTGATTGGCAGCAGCTTAA +TTCATAATAGCCAAAAAGTGGAAACAATAGCAATAGCCTTCAAAGAGTGAATGGTTAAAC +TCTTTCATCTATATGATGGAATAGTACTCAGGGATAAAAAAGAACAAAACTATCATTCAC +TCAACAAGCTAGATGAATCACCACAGAATTATTCTGAGTGAAGAAAAAACAATACAAAAA +GGCTATATACCACAATTTCATGATATATAACATTATTGAAATGATAAAATTATAGAAATA +GAGAAGAAAGTTGTGGTTGCCAGGGGCTAAGGAGGAGCTAGGTAGTGGTTGTGGCCACAA +GGCAGTATTAGGAATCTTTGATGATGGAAATATTGTTACCTTACTTAAATGTATCAATGT +CAATGTATTGATTGTGTTATGTATTCTATATGGTTTTGCAAGATGTTACCACTGGGAGAA +ACTAGGTAAGATGTACAAGAGATCTCTCTAGGCTACAGTAGTCCTCACTTACAGTTCCAC +TTTTGATGGTTTGAACCCAAAATGGGTTTCGTGGGTTTGTTACCCACGGCCAACCACTGT +CCAAAAATATTAAATGAAAAATTCCAGAAGTAAACACTCACACTTTTATTACAATATATG +GTGATAACTGTTCAATTTTATTATTATTTTGTTACTCTCTTACTGTGCCTAATTTAAAAC +TCAAATTTTATTATAGATATGTATGTACAGTCAGCCCTCCATATCTGTGGGTTCTGCCTT +TGCAGACTCAACCAACTTCAGGTGAAAATATCCTGGGAAGAAAACGATAAAAAAATACGG +ATACACACACAAAAAAATTGTAAAATACAGTATCACAACTATTTATATAGCATTTACATT +GTATCTAGTATTATAAGTAACCTAGAGATTATTTAAAGTATACAGAAGAATGTGCATAAG +TTACATGCAAATACATCATTTTATATAAGGGACTTGAGCATCCATGGATTTTTGGCATCC +ATAGGAGGTCATGGAACCAATCCCCCACAGATATTGACAGACAACCATGTAGGAAAAAAC +ATATATAGGGTTCAGGCCTCCATTGGGGGGGTCTTGGAATTTAGCCTCTGAGGATAAGGA +GGGACTACTATATTTTTTATAACCGCACGTCAATCTATATAGTTAGCTCAAAATAGTGTT +TTTTTGAACAACATTGCCCTTTGAAGGAATTATTAGCCAAAGCATGTCAGCAGATCTTTT +TTTCTTTGAGGCAGGGTCTCTCCCTGTTGCCTAGGCTGGAGTGTAGTGGCAGGATTATAC +CTCACTGCAGCCTTGTCACCAGATTTTAATACAGTGGCGTTTTGAACAATAGGAGTCCAA +CTTCTATTTTTTTCCACCTCTGCCATCCCTGAGAAAGACCAACCCTTCCTCTTCCTCCTC +AGCCTACTCAGTGTGAAGATGACAAGTCTGAAGACCTTTATGATCTACTTCCACTTACTG +AACAGTAAATAATTTTCTCTTCCTTGTGATTCTAGTAACATTCTTTTCTAGTTTACTTTT +AAAAATACAGTAAATAATACATATAACATATAAAATGTGTTAATCAACTGTTTGTTATCA +GTAAGACTTCGAATCAACAGTAGGCTATTAATAGTTAAGTTTTAGGGTAGTCAAAAGTTA +CACACAGATTTTTGACTGTGTGGAAGGTCAGTGCCCCTAACCCCTGTGTTGTTCAAGGGT +CAGCTGTATTTCTAATTTTCTTGTTGACAGGCAGAAGAGTTTACTAAGAAAATTCACCTC +TAACAATCTAGTTTCAAGGCATTTTCCAGGTGGTTTGTCATGTGCAGCTAGGAGCTAAAT +AGGCAAAGATGTAGAAGACAATGTAGATTTAGAAGAGAATATATAACACATTTTTATTAA +AGTATGAAGTTGAACAAGAACTCAGTACTGAACTCAAGATATTTTCATTATTCCTGCCCA +TAATCATGAATGCTTCTAAACAGAGCGCAGGCAGCACCTGACCAGTGTATGACCAACTCA +TGGAGAAGCAATTCTAAAGGAAGTCCTGTCTTCCTTACTTCCAGCCAGCCTAGGATACTT +CCCTATCAGAATCTTCCACTCCCAAGCCATCTCTGCAGCTCACCTCAGCCCTAACCACCC +CCAGCCCAAGTTGGCTAGGCAAAAAGAAGAGGAAGAAGAAAATGGTAAACATGTGCATGC +CACACCTGTTTACTCTTCTCTCCTGCCCGCCTTGCCACAATTCCTCTGAAGACGAACACC +CAAAGGAAGGAGAGGGTAGGAATGGCACAGGACTTGCTAACACCTCCAGCTGCCAGGCCT +CCTCTCACCAGTTATGAGGAAAGCCAGGCTTCATTCTTACCCCACCCCCACCAACTCTCA +CCTCCCTCAGCCTTCACAAAAAAACTCCACCCATACCTCCCCAATCCTATCCAGAAGCAT +TTCCAAAGTCCCTTCTTCCCTTTAAAACTAGTCTCCTGGGCCAGGCGACATGGCTCACGC +CTGTAATCTCAGCACTTTGGGAGGCCGAGACGGGCGGATCACGAGGTCAGGAGATCGAGA +CCAACCTGGCTAACACAGTGAAACCCCGTCTCTACCCAAAATACAAAAAATTAGCCGGGC +GTGGTGGCGGGCACCCATAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATGGCGTGA +ACCCGGGAGGCGGAGCTTGCAGTGAGCCGAGATCGCACCACTACACTCCAGCCTGGGCGA +CAGAGCAAGACTCTGTCTCAAAAAAAAAAAAGGCAAAAAAAAAAAACTAGTCTCCTCCAG +CTCTGCTGAAGCCCTGCCACAGGAGTCACATTCCAAGTAACCGGAAAGAAAATACAGAAT +GAATGTAATCCATCATTTGTGGATACCCTAACCCTCGCCTTATAGTAACTCTAGTTACTA +GAGCAACTAGGAAGCTCTCCTGAAATCGTAGTTCATTTTCTGGTGATTAGGTTACTTTCA +GAAATTAGAGGTTTCATTTATACTAAGAAACTTAATATGAAACTACTATTCCCACCTAAT +GAGCAAGAAATGCTTTCACTTATTAATATATCTTGCCAGGGCGAGGCACAGTGGCTTAGG +CCTGTAATCCCAGCATCCTGGGAGGTCGAGGCAGAGGGATCACTTGAGCTCAGGAGTTCA +AGACCAACCCAGGCAACATGGCAAAAACCCATCTCTACAAAAAATTAGCCAGGCATGGTG +GCACACACCTGTAGTCCCAGCTACTCGGGAGGCTGAGGTGGGAGAATCATCTGAGCCCAG +GAAGTCAAGGCTGCAGTGAGCCATGATTGTGCCACTGCACTCCAGCCTGGGTAATGGAGT +GAGACCCTGTCTCAAAAAAATAGAGAGAGAGAGAGAGACAGACAGACAGACAGACAGACA +GAGATAGGAGAAAGGGGGAGGGAGAGAGAGGTAGGGCAGAGAGAGAGGGAGAGGAGAGAG +GAGAGAGAAGAGAGAAAGAGAGAGAGATCTTGCCCATCTGGCTTTATTCTGAGACCCACC +GAGTGAAGCCTGTGGCAGACAAGAGTGGTTTCTATGAAAAAAATATAAATAAATAATAAA +TAAAAAGTGGTATTCCCAGATGTGAAGGCAAACTACAACAATGACAATGGCCTCTCTATT +GATTGGCAGGGTCAATTTGGCTGACAAGTTGGCTGGTCAGGTTTCTCATCTCCAGGTGCT +CTGCTTCCAAAGCTGGGAGTGGTACAAAGAGATTACATGGTCCTTGCACCAGAGTTCATC +TACTTTACTCAACCCCATAGTTTTACATTCAGTTCTAACAAATTTAGATGGTTTCCAAGT +TCAGTTAATCAGACAGAATAAATCTTCATAGAGAGAAAAACACTTTATTCATTCAACAAC +TATTTGTTGAGTGCCTAAGAAGTGCCAGACACTTGGAGATTCAGCAGTGACTGATACACA +ATGACCCCATCTCCTCCTGGCTTATGTGTGTTTGGTGGGAGGCAGAGGCAGAGGGTTAGA +CAGTAGAAAAGTAAATTAAAATTAAAATAATTGTAAATAAAATAATTACAACATGTTACG +GTGGCTAACAAGGACATAAACAGAGCTGAGGATCTTGCATTCTCAGAATTATGAAAAGCA +ATATTCAATCAAGGCCAGGCGCAGTGGCTCACACCTGTACTCCCACCACGTTAGGAGGCC +AAAGTGGGAGAATCCCTTGAGCCCAGGAGATCAAGACCAACAACATAGCAAGACCCCATC +TCTACAAAAAATAAAAATAAAAATAAAAAAATTAGCCAGGCATGGTGGTTGTGCCCACAT +TTCCAGCTACTCGGGAGGCTAAGGTGGGAGGATCGCTTGAGGCCTGGAGTTCAAGGCTGC +AGAGAGCTGAGATTGTGCCACTGAACTACAGCCTAGGTAAAAGAGTGAGACCACATCACA +CGCGAAAATAATTAAAAAACAAAAACTAAAAAACTAAAAGCAACTGATCTTTGAGAAGTG +ATAACTGCATTCTCAAAGTACCTAATCTCAACAATACCCTAACTTAAAACCTGCTGACTA +GGAGATGTATTTGACTGCAAATCTGGCCCACACAAGCAATAATCTGAGTTTCCATCAAGG +AAGCTGTAAGCACCAAGTAGAGCAAAAACAAATCCAGGCCTCAAATGGAAAAAGCAGCTC +TGAATTGTGATTTTCGAAGAAACCTGCATTTCTTACACTTCAGTGTACTTTCCCCATATT +TAACTCCAAGATTTTTGTTAATTTGTTTGGTTTTCCTTTCTCAAACAAAATTATGCTCAG +ACTGAAAACCCTAGATTTGTTCCCTATTGCATCTTCATTTCTTCCCAAACATTCCATAAA +ACGTGACCTACATTAAGTTAGCAAGTTAAGTCTGAAAGCGTCTACCTTCCCTGGGGAGGG +GGAAGGTGTAGGCAGGGCAGAGATTTGTAGTCCAGCCCTCTTGCCACAAATTATGAATTA +GAGAGGAATGACTTTGCTTTTTTAATGATCTCCAGAGAATTTTCCATCATTTCCCTCTCT +TCACCCAGCTCCTTTGCAACCACTGCCAGAGAAGTCTTCCTTTAGCTTCTTAAACATCGA +TCCTAAAACACTTCCAGACACCTGTGCTGCTCCTTTCAGTTCCCATGGAGATTAGGCTGT +GTAACAATCTCGCAAAGACGTTCCCCTCCGTCTCCTCATCCTCTTTTCAAACCCTTTTAC +GATTTCCCATCTCACTCAGCATGACAGTCAAAGTCCCTGTGATGGCCAACTTCTGCATCA +CCTAGCCAGTCTGCCACCGCCAAAACTCTCCAGCCTCATCTTTCTACTCTTCCCCTGGTT +CCTTGCCCACGCCTTTACACTTGTTCTCTGCTTGGAATCTTCCCTCCCCTCCTTGAGGAA +CTTTCTCAAATGTCACCTTCCCTCAATACTCCCCCTCCTCCATTTAAAACTATAAACTTC +CAACTCTCTAAGCCCCTAAAGTACTCTATATTTAACTTATTGTATAAACTACTGTCCCTA +CTTGTAAGTTCCAAGATTGCAGGGATTCACCCGCTTTGTTCACTGCTGTCTGCCAAGGTC +TAGAACAGTGCAAGTTACCCAACAGGAGTTCAATAAACAGCCATTCATTTAACAAATATT +TGCTGAGCACTTCGTCCCGTCCAAGTTTGTTAAATCAAGACAAATAAGACACCGTCCCTG +CCTTTAACGCACCAGATGGAGAAATGCACCACAGACATAAATGTGCAATACAGGCCTGAC +ACTACGGCCACAAGCAAGTCAAAGAACGTGCCAAAAGTTCAGAGGAAGAAGCCTCGGCTT +CGCCTTTCGGGAGACCAGTCCAGCTTTCCACCATCACGCTGCTCATCAGGGACCATCTCC +GGGGGTCTCCTCTAGACCCCAAGGGAGGAGCGGGTCCCGCCCGCCATTCCCAGGTCTCAG +AGTTTACTTGTCCAGAGATGCAACTTCCGGCCTCTTCAGGCCGGGCAAGATTTAAGGAAA +GAAAAGAAACATAAGGACCTCCGTTCTTCGGTCTCCGTCCCCTCCCCTTCCCCCGCGTGC +CGTCCCCACAACGGGCCAGGACTGAACCCAACTCTCGACCAACTCCCGGCAGCAAAACTA +AGCACCCTACTTCCGTTGTCCCCACCTGTTCCCGGCGTCCCCTTCGGCTACTCCCGGCGT +TTGCGCAAGCGGTCCCACGTGGGC diff --git a/test/csq/ENST00000409523/ENST00000409523.fa.fai b/test/csq/ENST00000409523/ENST00000409523.fa.fai new file mode 100644 index 0000000..ca688b8 --- /dev/null +++ b/test/csq/ENST00000409523/ENST00000409523.fa.fai @@ -0,0 +1 @@ +2 64644 25 60 61 diff --git a/test/csq/ENST00000409523/ENST00000409523.gff b/test/csq/ENST00000409523/ENST00000409523.gff new file mode 100644 index 0000000..744854b --- /dev/null +++ b/test/csq/ENST00000409523/ENST00000409523.gff @@ -0,0 +1,16 @@ +2 ensembl_havana gene 21 64624 . - . ID=gene:ENSG00000186132;Name=C2orf76;biotype=protein_coding;description=chromosome 2 open reading frame 76 [Source:HGNC Symbol%3BAcc:27017];gene_id=ENSG00000186132;logic_name=ensembl_havana_gene;version=10 +2 ensembl_havana transcript 240 64478 . - . ID=transcript:ENST00000409523;Parent=gene:ENSG00000186132;Name=C2orf76-004;biotype=protein_coding;ccdsid=CCDS42739.1;havana_transcript=OTTHUMT00000330585;havana_version=1;tag=basic;transcript_id=ENST00000409523;version=1 +2 ensembl_havana three_prime_UTR 240 267 . - . Parent=transcript:ENST00000409523 +2 ensembl_havana exon 240 344 . - . Parent=transcript:ENST00000409523;Name=ENSE00001581014;constitutive=0;ensembl_end_phase=-1;ensembl_phase=1;exon_id=ENSE00001581014;rank=6;version=1 +2 ensembl_havana CDS 268 344 . - 2 ID=CDS:ENSP00000386714;Parent=transcript:ENST00000409523;protein_id=ENSP00000386714 +2 ensembl_havana exon 9418 9499 . - . Parent=transcript:ENST00000409523;Name=ENSE00001335430;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00001335430;rank=5;version=1 +2 ensembl_havana CDS 9418 9499 . - 0 ID=CDS:ENSP00000386714;Parent=transcript:ENST00000409523;protein_id=ENSP00000386714 +2 ensembl_havana exon 15262 15299 . - . Parent=transcript:ENST00000409523;Name=ENSE00001335434;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00001335434;rank=4;version=1 +2 ensembl_havana CDS 15262 15299 . - 2 ID=CDS:ENSP00000386714;Parent=transcript:ENST00000409523;protein_id=ENSP00000386714 +2 ensembl_havana exon 18950 19000 . - . Parent=transcript:ENST00000409523;Name=ENSE00001335435;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00001335435;rank=3;version=1 +2 ensembl_havana CDS 18950 19000 . - 2 ID=CDS:ENSP00000386714;Parent=transcript:ENST00000409523;protein_id=ENSP00000386714 +2 ensembl_havana CDS 37623 37755 . - 0 ID=CDS:ENSP00000386714;Parent=transcript:ENST00000409523;protein_id=ENSP00000386714 +2 ensembl_havana exon 37623 37767 . - . Parent=transcript:ENST00000409523;Name=ENSE00003687102;constitutive=0;ensembl_end_phase=1;ensembl_phase=-1;exon_id=ENSE00003687102;rank=2;version=1 +2 ensembl_havana five_prime_UTR 37756 37767 . - . Parent=transcript:ENST00000409523 +2 ensembl_havana exon 64153 64478 . - . Parent=transcript:ENST00000409523;Name=ENSE00001584682;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001584682;rank=1;version=1 +2 ensembl_havana five_prime_UTR 64153 64478 . - . Parent=transcript:ENST00000409523 diff --git a/test/csq/ENST00000409523/ascii-art.txt b/test/csq/ENST00000409523/ascii-art.txt new file mode 100644 index 0000000..62b56fd --- /dev/null +++ b/test/csq/ENST00000409523/ascii-art.txt @@ -0,0 +1,30 @@ + + + 18990 19000 37744 37755 37767 + eeeeeeeeeeeiiiiiiiiii ... ..eeeeeeeeeeeeeeu....uuuuu +GTGGCAGGTTGGTCCTTAAAGGGATATCTACAAGAGA ... TCCAGGAGCCAT +GTGGCAGGTTGGTCCTT----------------GAGA C + + +CDS 268 344 .. 77 +CDS 9418 9499 82 .. 159 +CDS 15262 15299 38 .. 197 +CDS 18950 19000 51 .. 248 +CDS 37623 37755 133 .. 381 + + +GTGGCAGGTTGGTCCTTAAAGGGATATCTACAAGAGAAAGATTATTTTTTTACACAA +GTGGCAGGTTGGTCCTT----------------GAGAAAGATTATTTTTTTACACAA +GTGGCAGGTTGGTCCTTGAGAAAGATTATTTTTTTACACAA---------------- + 1234567890 + eeeeeeeeeeeiiiiiiiiii ... ..eeeeeeeeeeeeeeu....uuuuu + 12345678 + +xx: + CTACAAGA + GAGAAAGA + +a1: (null) aoff=11 +a2: (null) +a3: GAGAAAGA + diff --git a/test/csq/ENST00000409523/long-overlapping-del.txt b/test/csq/ENST00000409523/long-overlapping-del.txt new file mode 100644 index 0000000..715ce06 --- /dev/null +++ b/test/csq/ENST00000409523/long-overlapping-del.txt @@ -0,0 +1,6 @@ +18990 TAAAGGGATATCTACAA T frameshift&splice_acceptor|C2orf76|ENST00000409523|protein_coding +18990 TAAAGGGATATCTACAA T frameshift&splice_acceptor|C2orf76|ENST00000409523|protein_coding + +37744 T C synonymous|C2orf76|ENST00000409523|protein_coding|-|4G|37744T>C +37744 T C synonymous|C2orf76|ENST00000409523|protein_coding|-|4G|37744T>C + diff --git a/test/csq/ENST00000409523/long-overlapping-del.vcf b/test/csq/ENST00000409523/long-overlapping-del.vcf new file mode 100644 index 0000000..fe255a5 --- /dev/null +++ b/test/csq/ENST00000409523/long-overlapping-del.vcf @@ -0,0 +1,8 @@ +##fileformat=VCFv4.2 +##contig= +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO +2 18990 . TAAAGGGATATCTACAA T . . EXP=frameshift&splice_acceptor|C2orf76|ENST00000409523|protein_coding;type=ENST00000409523:120078770-TAAAGGGATATCTACAA-T +2 37744 . T C . . EXP=synonymous|C2orf76|ENST00000409523|protein_coding|-|4G|37744T>C;type=ENST00000409523:120097524-T-C diff --git a/test/csq/ENST00000410009/ENST00000410009.fa b/test/csq/ENST00000410009/ENST00000410009.fa new file mode 100644 index 0000000..bd808d4 --- /dev/null +++ b/test/csq/ENST00000410009/ENST00000410009.fa @@ -0,0 +1,96 @@ +>2 2:71057327-71062972 +AAAAGTGCACTTGGAGTGAGTCCTTGACCCAGGCAGCATTTTATTCTGAGGAAGCTGGAA +GGTGAATTCATGAAGGCACTGAAGGCTGCTTCCCATGCACAAGACACAGGAAGATAGGAA +ATGCAGAAGGAGGAGGAGGTGCCGGAGAGGTGAGGACAGGGGCTGGATGGACGCTGGGTG +GAAGGCAGGGCTCGGCACTCCAGTGTACTAAGGGAGTGGAAGGAGAAGGGAGGCTGGGTG +CCAGCCGAGCTCTGAAGGAGATACAAGTCCGTGTCAGCCACTGACTTGAACCAGAGAAGA +ACGGGTTCAGGCTTTAGATGATGTGGATGAAGAAACCACTGGGGACATACCATGAGCAGG +ATTTCCAAGAACAGAGCTATTTGCACTGCAAACACAGCCAGCTGCTAGCTGCCAGCACAG +CTAAGCAGAGACATGGAAATTCTAGGGGGTTTGGCCAAGAAAAGCCCTGGATGACAATAT +CAGGAGAATTGCTTGGTTGCTCTGGAGTAACTTTGATGTGATGAAGCTGAGGTTTCTCTG +AAAGAGTGGAAAACCCCAGGGTGTTATGCCGGATTACGGGTCTTGATCCTCCTTAGCAGG +GCAATTGGAACTTCTAAATCCTCTCTACCCACCCCTCCCACTTTAACCTGAATTCTCCTT +TCCATTCCAGCTGCCTCCAAGACGTCAGAGAATTTCCAGCCAAGACAGACGGACTCCAGA +ATGCCACTGTGGGACAATTTTGAAGCAAGAAAAATTAACGTGCAAAGTCATCCTGGAGTC +TGGGGAAGAAAGAGGCATTTCCTCATGTTTAACAAGCGTTGGAGCTCAAAGAGTGAGCTT +GGGAGCCTGTCCTGTCACGGTTCTGATGGGACATAGGGTCGCTTACAAATGAAAAGAAAC +GTTTTGTCACATGGGGCATCATTCCAGGCCTGAAGTGAGGGAGCCTTTATATTGCCACAG +TGTTCATTGTTCCCAGCATTGTTGGGCTCACCTGGAATCCAGAACCTACCAAGAGCGGGG +AAAAAGATGGATTTACAAAGTGGAAAATCAAAAAGAACTTATTTCCAGTGAAGAAATGAG +TTAACTCAACCCAAGCTTTTGTCCTAGGGAATGGCATAGCAAATGTCTGCACCCAAGCCT +CAGAGGAAGGGGACTGGTGAGACTTCGACCTCTAAGCTTTCACATGCCCCAAGTCCAGGC +CAAACCAACCCACCACTTTCAAGTCCCTACACAAACCCACACTGTGAAGACCTAGACTCA +TGACAAGATCCCTGAAGCTGGCCAGGTAGAAGGCCTTGTTGCCAAACCCCAGAGGGCGTG +GAGGGCTCAGGTCCACAGCCAGTTGGTGACAGGGTTGTGCTCGATCTTGGTTGCAATGTT +CCTGTCACTCTAAGACAGGGAAGAATCAGAAACCCTGTCTCATGGGGAACATCGCCCCCA +CTCCCTTCATGCCCTGGCCATGGCCGGGGAAAGTCAGGCTGGCACGGAGGGCTCCAGGGG +CTTACCTCACACTTTGGACCTTGTTGAATGGCGTGTCATCCACCCAGGACCAGTCCCCTT +CCATCCCTGCTTTAGTCAGGCCAATCCAGTAGATGAGTCCCCCCGCTGTTTTATACAGAA +ACTCCTGTAGGAAAGACAGGATAAGCAGAGGTGCGGCCACACTTGGAGCTTGATCATCTG +TCTCTGGGTGTTCTTCACCTGCGCTCAGTGACAGCCCTGACCCACAGATGCGCTGCACAA +ACTGGCCTCTCAAGCTTCTTCCTGCCCTTGCCCAGAGCCCAGATTTCATCTTCCAGATTA +TGATGTGTCCCTGCTCTGCAGCTAACAAGCTCAGGACTCAAGCCTTTCTGCCACTCAGGA +AGCAGGTGCTGAAGCACAGGAAGGCCTCAGCTGAACTCCAGAGCACGGACCGCAAGAGAA +TGGTTCATATGATAATACCTGAATTAAATGAGCCCTGAATCCACATACGGCACTGTGCTG +AGTCGTCCATATGCATTCTCTCCTTTCCTCTGAGGCAGGTGCCATCACCATGCATGTTTC +ATCAAGTGAGGGCCAGTGAAGTTTGCCCAGTGAAGTTGGGTATTCCACCCAAGCTGCTAG +GACTAGTTAGATGGCAAGGTTCAGGCTCTAGAACTACGCCAGAGCCCAGGCTCTGACCTG +CTCTGCTATCCCACCTCCCAGATGAAAAGGGCCTGCCCAATTTCTGCCTCACCAGGCAGG +AGACTTCTTGAGTCATGTGGAATCATTAAGGCTGTTCACAAATATTTCTTTTTTTCTGGG +CACATGGAAAGTAGATCCTCTCTGCCCTGTTCCAGGAGTACTGGAATCCAGGATCCTCCC +AATCCAGGAGTACTGCATAACTTACTTAACTTAATTAACATAACTTAAGCTAGTGAAATG +TAAGCAAAAATGAGGTATGTTAAATCTGGGCAGAAGCTTTGCACAATATGTCAAGTTCCC +CTTTCCTGCCCCAGCAATTGTGGAGACATATTAAGATGAAGACTCCTTGGGCCTGGGTCC +TTGAGTAGCCACAGTGAGCACAGCCCCCTTGCCGGCCCTTATTCGACATGCTACTGAGAA +CCAATCCTTCTTCATTAGGTCATCAATATTTGGGGATTTTTGTTCACGCAGTATAATCTT +GCCCATCCTCCCTGGCCCAGTGCTCATACGCCCCCTTCACAGAGCCCATAGGCACAGCAC +TCACCTGCTCACTCTCTGAGGTCACCGAGGTCAGGTGTGAATTCCTGGACACACAGAACT +GCTCGGCACTATACCAGGTCTTTGGAATGAGAGAAAAGTAATAGAAGTTCCCCTTGAAGT +ACTTCCAGCCTTGAGAAACCACCTGTAGAATATCATCTAGAGAACAAGAGGTAAAAGTGA +ACGCTGGTATTCTTGATTTCTTGGGATGCTGGCTTGGTGGGGGCACTTGAATGAGGTCTC +AGAGACAGCAGCAAATGGAGCTGTGCGCTGGTGTCCTTGGGTCCTTGTATAGGAGATTAG +GGACACTCTTTCAAATCCTGAAAGTCAGACAGAGACTAATAGAGTCTCTGGGACTGGAGA +GGTTATAATGCAAGAGGTTGGACAAAGAGTGTCTTCCCCATGATGAGGAAGCAACCCTCC +ATCGGCCATGACAAGTGGCTGAGCCCCTGGACTCTAGAAAGGAACTTGATGGGAAATGAC +TAGGTGTGGGCCAGGGTGGACATCCCCTAATGCTTTTACATTCTGCACTTTTGTGTGGGA +GCTCTAGCTGGACCCTGGTCTCTTTTCTCCTAACAGCCCCTAAGTCCTCCCCAACCTCAA +GCCCTCTCTCCTTAACTTCCTAGCCCATGGCTGCCCCTCTTTTGCCCCCACTCTCCTCCC +CAACCCACCAGCCCAATGGCCTCAGGTCTGGGACAGGTAAGATCCCATGGGCCACTGGTC +AGCTTCAATGTAATTTTCTGAGTCACTTACTTTGTCGTTTGAGCAACTTGCTCATATTCT +CCAAGCTGCCCTGGAGTGCCCGGATCTTTGTATTTAAAGCACTGGCTTTCTCCAAATCAC +TTTTTAACTCTGGGATTTGGGCATTTAAGGTACTGACTTCTTCCCAACTTCTTGTTAAGA +TCTGGATCTGTGCGTTGGCCTTCTCCACACTGGTTTTTAACTTCAGGAACTGAGAACGCA +CATAACCCAGGCTCTCATTCACCATCTGGATCTGAACGCCAGCTGCCTCCATGCCGTCAC +TATTCTTTTTAATTTCAGAATCCAGGGTGCTGATGTTGTCCACACGACCTTTCAGCAACT +GGACATTGGTCTTTACATCTGATATGGTGCCCATAAACCGGGGATCTGGGATTGAGAAAG +TCAGGAGGTCAGCTGAGGGGAGTCCCAGGGACAGGAGTGGGGGTGTTGTCAGGTTGATCA +AAGGAAGGGAAGGAATAGGCTGAAGCTTCCCAAAGAACCAAGACAGTCCAATGGGCCACC +CCAACCCTCCAATCATTCATTAACGTACAACAAACGTGCAATGGGCACCTACCATGTGCC +AGGAACACAGGTGGATACAGATAATGGGGAGATTGATAAAACACAGGCTCTCTGTGAAAA +GATTTCACAGGCAAGCAGAAGCAGGAGTTAGAAACCATTCCTGAATTTTCTGAGTGTTCA +GGGAACATTTGATAAAGGGTGCCCTCCATGAGCCCCACCACTGTCCCCAGAACTTGATTC +CCCCTAGACCCCACCCCTTGGTTGCCATCCCTCTGTTTTCAGAAACCCCTGCAGTGGCCA +TCTGCTAGGACAGCACCACTCCCCCACATCTGTCCATGGGCCCCTCTGTGACCATGGGAA +GAACCAGCCACTAATCTGGAAGTGGCTTCTCCAGAGAACATGGAAGAGGAGATTACAAAA +CTGTTTCTCCCCTTCCCTTGCCCCACCCACTTTCACATTCTGCTCAGGTCCCAGGCCTGG +GTACCAGAGAGAGGATCAAAGATAAACCAAGAGGCTCAAAGGCGAGCCCTGAGGAAAATG +CGATGTTAGAGGCCAGGGGTCTAGGATGGGGCAAGGGGGACTCTGCTCAGAGCCTACAAG +TCTAAGCCCAAATATGTCCCGAGGCCACAGAGGGAGAAAAAAAAACCCAACAGCTTCTTG +GGTCCCTTTGCTCTGCTTCCTGGAGCCCTGGCAGGAGGAAGAAGGCTCTGCCAGCAGCAA +AGGCCATGAAGCCTGACAGAGCCAGAAAAGGAAGAAAGATAAACCATGCAACATCAAATG +AGCAGGAAGCCTCCCTAGATGTGATCTTCACAGGGACAGGAGAATGAAGACAGCACCAAC +GAGTCCTGGGGAGAGGGGACTGAGTCATGGAGATCTGTTGGCTCGTTGGCCAGGCTCTCC +ATCTGGTGAGCTGGGGCCAATGATACATGAGGCTCGGTCCTTCACAGGGTCAGGAGACAT +TGCACTGTCAAGGACTGTCCACAAGGCTCTAGATCCAAGGAGCAGAGCTCAGATTGGTGG +GGGGTGGACGGGGAGAAAATAGCACAGGATGTAAAACTAGATCAATGTTTCCTGAGGACA +AAAGAATGTATCCTTGAGCACCAATGTGCAAATGCTAATCCCAATAATCTCCCAGAAATT +GGGAGGGAAAGAGCATCAGCTCACCGTACTGGGGGCAGCACAGCCTGTTACTGCACATGG +AAAGAGGAGGAAGGAGACAAATGAAAAAGCCACAGGCAGGAGAAACCCGGAGAGCAGGGA +AGTGGTCTCGATCTGAAGGGAGCCGGCTGGCCACAGAGAGGGGCTAAGCCCAGACGATGA +AACATGAGGACTTACAAAGGACGGCCTGCAGCAGGACGGAGGCGACCAGGACCAGCGTCA +GGCAGATTAATGCAGCACGGACTGTGGGTGTTTTCCCCGGGACCAGAGATGGACCGGACT +TGGGAGGAGGCTCTGTTGGAAGAAGAAGAAAATGTGTGTTGAAGGAGCAGCAAAGGGCAG +GTTTGCACACAGAACACGGAGCAGGTTCTCAGCAGCGATGTGGCTTGCTCGGGGCCAGAG +GGAGATGTTCTGTTTGTCCACAGTGAAGTGCGCATCAGGGGCCTCCTTCTCCACAGTCAT +CCTGAGTGCTCACCCTTATCCTGGGAGCACAGGTGCTTCTGGCTGCCTGTCTCTCCAAGG +GCTCTT diff --git a/test/csq/ENST00000410009/ENST00000410009.fa.fai b/test/csq/ENST00000410009/ENST00000410009.fa.fai new file mode 100644 index 0000000..d08e1f4 --- /dev/null +++ b/test/csq/ENST00000410009/ENST00000410009.fa.fai @@ -0,0 +1 @@ +2 5646 23 60 61 diff --git a/test/csq/ENST00000410009/ENST00000410009.gff b/test/csq/ENST00000410009/ENST00000410009.gff new file mode 100644 index 0000000..3e7c2dd --- /dev/null +++ b/test/csq/ENST00000410009/ENST00000410009.gff @@ -0,0 +1,16 @@ +2 ensembl_havana gene 21 5626 . - . ID=gene:ENSG00000116031;Name=CD207;biotype=protein_coding;description=CD207 molecule%2C langerin [Source:HGNC Symbol%3BAcc:17935];gene_id=ENSG00000116031;logic_name=ensembl_havana_gene;version=7 +2 ensembl_havana transcript 21 5626 . - . ID=transcript:ENST00000410009;Parent=gene:ENSG00000116031;Name=CD207-001;biotype=protein_coding;havana_transcript=OTTHUMT00000329959;havana_version=4;tag=basic;transcript_id=ENST00000410009;version=3 +2 ensembl_havana three_prime_UTR 21 854 . - . Parent=transcript:ENST00000410009 +2 ensembl_havana exon 21 1005 . - . Parent=transcript:ENST00000410009;Name=ENSE00001949188;constitutive=1;ensembl_end_phase=-1;ensembl_phase=2;exon_id=ENSE00001949188;rank=6;version=1 +2 ensembl_havana CDS 855 1005 . - 1 ID=CDS:ENSP00000386378;Parent=transcript:ENST00000410009;protein_id=ENSP00000386378 +2 ensembl_havana exon 1506 1624 . - . Parent=transcript:ENST00000410009;Name=ENSE00000760756;constitutive=1;ensembl_end_phase=2;ensembl_phase=0;exon_id=ENSE00000760756;rank=5;version=1 +2 ensembl_havana CDS 1506 1624 . - 0 ID=CDS:ENSP00000386378;Parent=transcript:ENST00000410009;protein_id=ENSP00000386378 +2 ensembl_havana exon 2705 2856 . - . Parent=transcript:ENST00000410009;Name=ENSE00000760757;constitutive=1;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00000760757;rank=4;version=1 +2 ensembl_havana CDS 2705 2856 . - 2 ID=CDS:ENSP00000386378;Parent=transcript:ENST00000410009;protein_id=ENSP00000386378 +2 ensembl_havana exon 3451 3825 . - . Parent=transcript:ENST00000410009;Name=ENSE00000760758;constitutive=1;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00000760758;rank=3;version=1 +2 ensembl_havana CDS 3451 3825 . - 2 ID=CDS:ENSP00000386378;Parent=transcript:ENST00000410009;protein_id=ENSP00000386378 +2 ensembl_havana exon 5296 5412 . - . Parent=transcript:ENST00000410009;Name=ENSE00001588982;constitutive=1;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00001588982;rank=2;version=1 +2 ensembl_havana CDS 5296 5412 . - 2 ID=CDS:ENSP00000386378;Parent=transcript:ENST00000410009;protein_id=ENSP00000386378 +2 ensembl_havana CDS 5508 5580 . - 0 ID=CDS:ENSP00000386378;Parent=transcript:ENST00000410009;protein_id=ENSP00000386378 +2 ensembl_havana exon 5508 5626 . - . Parent=transcript:ENST00000410009;Name=ENSE00001589135;constitutive=1;ensembl_end_phase=1;ensembl_phase=-1;exon_id=ENSE00001589135;rank=1;version=3 +2 ensembl_havana five_prime_UTR 5581 5626 . - . Parent=transcript:ENST00000410009 diff --git a/test/csq/ENST00000410009/ascii-art.txt b/test/csq/ENST00000410009/ascii-art.txt new file mode 100644 index 0000000..37a22fd --- /dev/null +++ b/test/csq/ENST00000410009/ascii-art.txt @@ -0,0 +1,7 @@ + + 5507 +ref CTTG.CT +alt CTTG.CCT <-- this one is correct + CTTGC.CT + iiii.eeeee + diff --git a/test/csq/ENST00000410009/frameshift.txt b/test/csq/ENST00000410009/frameshift.txt new file mode 100644 index 0000000..c12b028 --- /dev/null +++ b/test/csq/ENST00000410009/frameshift.txt @@ -0,0 +1,3 @@ +5507 G GC frameshift|CD207|ENST00000410009|protein_coding|-|25EPPPKSGPSLVPGKTPTVRAALICLTLVLVASVLLQAVLYPRFMGTISDVKTNVQLLKGRVDNISTLDSEIKKNSDGMEAAGVQIQMVNESLGYVRSQFLKLKTSVEKANAQIQILTRSWEEVSTLNAQIPELKSDLEKASALNTKIRALQGSLENMSKLLKRQNDILQVVSQGWKYFKGNFYYFSLIPKTWYSAEQFCVSRNSHLTSVTSESEQEFLYKTAGGLIYWIGLTKAGMEGDWSWVDDTPFNKVQSVRFWIPGEPNNAGNNEHCGNIKAPSLQAWNDAPCDKTFLFICKRPYVPSEP*>25GASSQVRSISGPGENTHSPCCINLPDAGPGRLRPAAGRPLSPVYGHHIRCKDQCPVAERSCGQHQHPGF*|5507G>GC,splice_region|CD207|ENST00000410009|protein_coding +5507 G GC frameshift|CD207|ENST00000410009|protein_coding|-|25EPPPKSGPSLVPGKTPTVRAALICLTLVLVASVLLQAVLYPRFMGTISDVKTNVQLLKGRVDNISTLDSEIKKNSDGMEAAGVQIQMVNESLGYVRSQFLKLKTSVEKANAQIQILTRSWEEVSTLNAQIPELKSDLEKASALNTKIRALQGSLENMSKLLKRQNDILQVVSQGWKYFKGNFYYFSLIPKTWYSAEQFCVSRNSHLTSVTSESEQEFLYKTAGGLIYWIGLTKAGMEGDWSWVDDTPFNKVQSVRFWIPGEPNNAGNNEHCGNIKAPSLQAWNDAPCDKTFLFICKRPYVPSEP*>25GASSQVRSISGPGENTHSPCCINLPDAGPGRLRPAAGRPLSPVYGHHIRCKDQCPVAERSCGQHQHPGF*|5507G>GC,splice_region|CD207|ENST00000410009|protein_coding + diff --git a/test/csq/ENST00000410009/frameshift.vcf b/test/csq/ENST00000410009/frameshift.vcf new file mode 100644 index 0000000..111ea9a --- /dev/null +++ b/test/csq/ENST00000410009/frameshift.vcf @@ -0,0 +1,7 @@ +##fileformat=VCFv4.2 +##contig= +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO +2 5507 . G GC . . EXP=frameshift|CD207|ENST00000410009|protein_coding|-|25EPPPKSGPSLVPGKTPTVRAALICLTLVLVASVLLQAVLYPRFMGTISDVKTNVQLLKGRVDNISTLDSEIKKNSDGMEAAGVQIQMVNESLGYVRSQFLKLKTSVEKANAQIQILTRSWEEVSTLNAQIPELKSDLEKASALNTKIRALQGSLENMSKLLKRQNDILQVVSQGWKYFKGNFYYFSLIPKTWYSAEQFCVSRNSHLTSVTSESEQEFLYKTAGGLIYWIGLTKAGMEGDWSWVDDTPFNKVQSVRFWIPGEPNNAGNNEHCGNIKAPSLQAWNDAPCDKTFLFICKRPYVPSEP*>25GASSQVRSISGPGENTHSPCCINLPDAGPGRLRPAAGRPLSPVYGHHIRCKDQCPVAERSCGQHQHPGF*|5507G>GC,splice_region|CD207|ENST00000410009|protein_coding;type=ENST00000410009:71062833-G-GC, ambiguous, can be frameshift or a splice diff --git a/test/csq/ENST00000413103/ENST00000413103.fa b/test/csq/ENST00000413103/ENST00000413103.fa new file mode 100644 index 0000000..3cd46ea --- /dev/null +++ b/test/csq/ENST00000413103/ENST00000413103.fa @@ -0,0 +1,29 @@ +>1 1:94713444-94715068 +GCGCCCGGCCTGAAGTTGTCCCAACCGCGGCCGCGTCGGTCGCCCTTTTGACTTGCAGCA +GGGCGGGCAGAGCGACTTAGAGGAAAAGTGACTTTTTGTACCCTCCTGCAGGGAGCAGGT +TCTCTGTCCTTGTTTAATTAGACATTTCTCAGGTGGGCACTTTGAATTCCTTCCAGTCAA +GACTCAGGTGTTCAACTTGTTTTGTCGGCCGTCTTCCTCCACCCTTCTTCTCCCATTCAA +AACAAAAGTACGTTTTGTGCTTAACTTTAAAACTCCCCCCACTCTTTTCTGTCTTCAACT +GATTGTCACTTTCAGCAAACCAAATAAATTACTCAAAACATCAGCTATTATACAGTCCCC +GACACATGGCAGGTGCTCAGTAGATGCTAGTTGATCGCATGTCCCCTAACCACGCTACCT +GCTTCTTACCATTAAGTGCTCCTTCAGTCATGGGACTGATCAACACGGTGGAGGAAGCCG +CAACCAAAATAAAACATTTATCTAGATGTTGGATCACACATCATATCATGTATGGAGGAA +AACAAAACACTGCATTTATATATAATATATATTAGTAACACTTACCAACTCTACTAAGAA +TACCTTTCCTGTCACCTGTGCTGACACATAAGCACTCCATGAATATTAGCTGATTAATGG +GTAAAATTATGGAAAGGGAATTTGGAAAAATCACTTAATGGCATCTTCCCTTTAAATATT +TTTCAAAAAGATTAAATATCTGTCATATTCTTCACCCTTCTTCGTTAGGAGAAATATATT +TGAAAACATTGTCAAAGGAAGATGTTTTTGTTTTGTTTTGTTTTGTTTTAGAGAGAGACA +GGGCCTTGCTCTGTGCTCAGGCTGGAGTGCAGTGGCACAGTCATAGCTCACTGAAGCCTT +GAACTCCTGGACTAAAGGAATACTCCCATCTCAGCCTCCTGAGTAGCTGGGACTACAGGC +TTGTGTCACCACACCCAGCTAGCTCTGTTGTTTATTTTTATGTTTTGTGGAGATGGAGTC +TTCGCCATGTTGCCCAGGCTGGTCTCAAACTCCTGGCCTCAAGGGATCCTCCTGCCTCAT +CCTCCCAAAGTGCTGGGATTAGAGGCATGAGCTACCACACCTGGGTCATTTTTATAAGTA +AATATGATTATTAACTGAGAAAGGGTGAATGTCAAACATCTGCTATGTGGGATAAATGGC +TGTGTTTGGCAAAGAAACTAAAAAATAAGGGGCAATATCTCCACCAAATCCTCTAACACT +GACTCAGCATGTGCCCTGAATCATCTTATAAGCCAACTAGGTTTTTTACCTATAAATGTT +TCTTCACTAAAGTGGCTCATGATCATGGTTTTGGAGGACGAGGACTAACAGACACACAAA +CAAGAAATCAAAGGCATAACTGGATAGTGCATTAATAATGAAGCATGTATGACAGATGAT +GTGGTATTGTTATTTTATAATTACAGTATATATTAACACATATCCACTCTGCTTATTGAA +ATATTTTTCATTCCTTCCATGATAGAGAATCCTGCCTCTGCTCTGAAGCCTTTCTGTTCG +CTCCAGTGAAAATTAGTCATCCACCGGGCGCGGTGGCTCACGCCTGCAATCCCAGCACTT +TGGGA diff --git a/test/csq/ENST00000413103/ENST00000413103.fa.fai b/test/csq/ENST00000413103/ENST00000413103.fa.fai new file mode 100644 index 0000000..f1f8983 --- /dev/null +++ b/test/csq/ENST00000413103/ENST00000413103.fa.fai @@ -0,0 +1 @@ +1 1625 23 60 61 diff --git a/test/csq/ENST00000413103/ENST00000413103.gff b/test/csq/ENST00000413103/ENST00000413103.gff new file mode 100644 index 0000000..2115f42 --- /dev/null +++ b/test/csq/ENST00000413103/ENST00000413103.gff @@ -0,0 +1,4 @@ +1 havana lincRNA_gene 21 1605 . + . ID=gene:ENSG00000231363;Name=RP11-148B18.1;biotype=lincRNA;gene_id=ENSG00000231363;logic_name=havana;version=1 +1 havana lincRNA 21 1605 . + . ID=transcript:ENST00000413103;Parent=gene:ENSG00000231363;Name=RP11-148B18.1-001;biotype=lincRNA;havana_transcript=OTTHUMT00000029383;havana_version=1;tag=basic;transcript_id=ENST00000413103;version=1 +1 havana exon 21 152 . + . Parent=transcript:ENST00000413103;Name=ENSE00001743123;constitutive=1;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001743123;rank=1;version=1 +1 havana exon 1526 1605 . + . Parent=transcript:ENST00000413103;Name=ENSE00001669492;constitutive=1;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001669492;rank=2;version=1 diff --git a/test/csq/ENST00000413103/long-deletion.txt b/test/csq/ENST00000413103/long-deletion.txt new file mode 100644 index 0000000..faaa4d9 --- /dev/null +++ b/test/csq/ENST00000413103/long-deletion.txt @@ -0,0 +1,3 @@ +17 TGTCCCAACCGCGGCCGC T non_coding|RP11-148B18.1||lincRNA +17 TGTCCCAACCGCGGCCGC T non_coding|RP11-148B18.1||lincRNA + diff --git a/test/csq/ENST00000413103/long-deletion.vcf b/test/csq/ENST00000413103/long-deletion.vcf new file mode 100644 index 0000000..48e2626 --- /dev/null +++ b/test/csq/ENST00000413103/long-deletion.vcf @@ -0,0 +1,7 @@ +##fileformat=VCFv4.2 +##contig= +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO +1 17 . TGTCCCAACCGCGGCCGC T . . EXP=non_coding|RP11-148B18.1||lincRNA;type=ENST00000413103:94713460-TGTCCCAACCGCGGCCGC-T, starts well before ex_beg diff --git a/test/csq/ENST00000420670/ENST00000420670.fa b/test/csq/ENST00000420670/ENST00000420670.fa new file mode 100644 index 0000000..b96b72a --- /dev/null +++ b/test/csq/ENST00000420670/ENST00000420670.fa @@ -0,0 +1,2291 @@ +>9 9:91975682-92113065 +GCCAAGTACAGTCATTTAACTGAACAATGTACAACTCTATTTTTATTTTTTCCAGCAGAG +CAAAGAAAGACTCAGAAATTCATCCTCATAACTCCATTTCCCAGTAGAACACTCCACATT +ACGAAAACTTCAAGTATGTAATTATTTTGTTAAGTGTGAAAGTGCTTGAAATCCAGACTT +CAGGAGAAGAGACAGAAAACAGCACCAAGAATATAAGCCTAAAGCCCATAGCATTTCACT +CATCAGTTTGTAGTGGTTGAAGCCACACCCAAAGCAAGAACCACAGTGAGCTGATGGATA +TTTTACAGGAAAACTTCAGGTTATGAGTATGTGATGGTTCCGTGAGCAAGACTGGCATCC +TTGGCTGGATGGGCAAGCACACACCTCACAGGCAGCTGGGCCTCTCGACTTGGGGTGCGG +AGGGGGAACGTGTGGAGACAACCAGGGTGTCTCCAGCATCTTCAGGACACCTGTTGTGAT +GGATCCTGAAGGAATTAGCAGGCGATGTATGCTGATCCCACACAAAGGCTGGTAGAGAAT +TTGTCCAGCTCCAGAAAGAGGGGATGCAAAACAGGTCATTGTCACACTGCTGGGAAGACA +CTCAGTATTTGCTAGGATCACCAGAGGGGTGCGGCTTGACTTTTAACAGAGGCTTTGGTT +TTATGATAGACATGAAAACTGTCATTCAACAGACAAGAAGAGACGTGTGTGTAAGATTAA +AGGCTGAGTAGCTTTAGGACAAGTTCACACACACAGTGACACAGTCTTCAGAGATACAGC +TTTAATAATTAGAGACTTGAAAGCAGGTAGAACAAAACACTCATGAGACTCATTCCATCG +TCAAGAAATTTAATATGGCACCAGGAGATTTGCATAATTGACCTATTTGGCTTTCTGCAT +CAAGTTTGGTGTCCTGTTGCAGAAGCTGAGCATTGACGGGACAGAGGCATAAACTGCAGC +GCTTGATAAAATAGAGCCCAGTATTCTGAGGTTAGTGAAGAAAACACAAAGACTTGACAG +ATGCACTCCCAGATCGCATCTCACAGTCATTCAAGGTTTAGGGCAAGGCATTTCCATGTG +GAGTCTCACCTTTTCTTGTCCCAGTCATGCATCTTGGAGTTCCTTGGCTAAGTCTGCAGG +GAGGAGAAGCAGCAGGCTTGATTTGCATCAATAAAAGCAGCGATCTGTGCTGGCCATGCT +AACCCTGTTGGCTATTAGGGGGTGGGGGCACTCTGTCAAGGGGAGTCACTGGGACGGTGT +AGGATCAGCCTTCAGAGCCTGCTGCCTGACCGTAGAGGAGGAACCTGCACACACCCTGCT +GTTTTAGTTCACGAGCAGCTATCAAAGCCTGTTAGCCATCCTGGTTACCTGCTTGTGCCA +GACAGAACTTACTGTCCCAGGTAAGCACCTAATTTTTTAAGTCTTAGTTCCTGTCACAGG +CCCACTTGGGTTCCAGGCTTCTCCACTGTCCCGCCTCTGCCCATCAGGTGGTGGCCCAAT +GGCTGTGTTCAGAGCAGGCTTGGGCAAGACAGTTCACAGTTGTGGGGGACCAGGCCTTCT +CCGGGGGTGGCTGTGGTCAGTGGCAGCAGGGTCTTGTTGGGGTTGAGGTCGGTGTCAGGG +ACTCCTTCCTGGTGGCTACAGGGTGTCCTTGCTACAGCTTTCCTGAAAGAACAATGTGGT +CTTTGAATCCTTGGTGGAACGGATGGGCCTTTCCTGCTCTGCAGCCCAGTCTGTCTCATA +GCCCATCCCAGGCAGAGCACTCAAGGCCTCAGCCCCCTGTTGTGGTTCCCCTCCTTGGAG +TCTAAAGATCCAAATGCCAGGAGTGGTTCTCCCATATGTGACAGGAAGGCAGAGCAGCAG +CGCATTCACTCCACTCCCAGATTGTGCTGAGAGGCAGGAGGGCTGGAGAGAGGGAGCCTG +TGTGTGCTGAAGTACAGAGGATCAGCTGTAAATGCCCAGCCTTTGGTGGCAACAGTTCGG +GGGTGTACTGCTGGCAGCCACGTAACCCACACACTTTAATGCACTCATTTGAGTGCTGCA +GACCCCACCGCAGGTGGTAGCACACAGTGATGAATCCCTGCCTTTGCCTTCTGTATCGGC +TATTTAGGAGCCGGGGCTGGACAACTTTGTCTCCGTGGGGAGACAGGGAGCCTCTAGGGA +GCCTCTGCCCCACTGCCTGCAGCTTCCATGCTGTAGCCCAGTTCCTGCCAGGGCTTAGCT +CAGGAAGCCACTCCCCCTGACCCCTCCAACAGGTGCCTCAGGTGAGGCATCCAGCCAGGA +GCTACCTGGAGGGTTCCCCATCTGTCCAGGTTTCCTGCCCTCCTCAAAGGAGTGGCTGGC +TGAGTGCTCTGTACAGAGAATGGGGTGGTCGTGGGGGCCCATCTAACTAGACAGCCCCAC +CTGTGAGTCCCTCCCAGTCTCGCCTCCCTTCAGTCTCTTTTAAGGGCTGGGGCCAGATGC +CCCTTGATCTCCTGCAGTCTCAGCAACAAGACGTGGGATTTCCCCCCCCAGTGTTGCAGA +TTTCATAAAGGAAACTGCTCCGGGGCTAAGAGGGAACAAGTGGGGTCCATGCTGAATGGG +GCCCTTGAAAGATCCACTGGATGTGGCAGGTGCCCTGCCCCTGGCTCCAGCCCTCCTTTC +TTTGCCCGGCTGCGGCCACTTACCCACGCCTTCCTCCAGCTCTGCATCATCCGGTCGTGC +TCCCCAGCCACAGCCCTCCAGGCAGAGAGCTCTCTGGTCCACCTCTCCTGGTGGGTCACT +TCTGGAAAACAAGCAGGGTCCCCAGGTCAAAGCTCTGTGGGCCTTTATGGCACCCTTGAT +GCCCACTGGCCACCTTTCTCAATGGAAAGCCAATAAAACCCAAACCCAGAATGCCACCGT +GCAAGCATGCTTTCCAGCTGTTTTTTTCACTGCCATTGTAAATAGTGAAAAATTACCTCA +TAAAAGGGTAACAGTGGGCATGGGAATCACTTACCAGGTCTCATCACAGCAACCTGCACC +TTCGAAGTCTTGTTCCCTGCTGAGGAGAGGACAGAGCAGCGATACTCAGCGCTTTCCCTG +ATGGCGTCCTGCAGCCAGCTGAGTGCATGGGCCCTGCCATCGGGCAGTGCATGGGTCTGC +ACAGGGACACAGGTCTCCAGAGCTCGCCCATTCTTCTCCCAGACAAAGCGAATGTCTGCA +GGACCTGGGGACACAGACCGTTTCCACCTCTGAGTCCACATTTAGGACCCAAAGAAGCTG +CCCCATGAGGGTGCAGGGGGGTTACCTCTGCTGTCCCAGTTGGACCTGAAGTGACTTGGG +ACAACTTCCAATTCAGTCCCTGGGACTGCCCTGGAGGTGGCTTCCCCATGGCCAGCGGGA +GCCTTGGCCTTGGCCCGTCCTGTGGACTTCCTGCTCTTTGACCTTAATTGCCATTTTTCA +AAGCACACCTGTGTGGCCTGTGTCCCCTAGGACCCCCTTTCTTGCAGCGCTGTGCTGGTT +TCTTACAGAATGGTTCTGGGCCTTGGAACAGCATCCCACCCCACCATGGCCCTGCTGCCA +CACACATGTCCTGTGACCACATGGACAGAGACATCCCAAGGCTCTGCCATCACCAGGGCC +ACAGCATGGAGAGGCCCAGAGCTCGGCCAGCTGTGTGCAGAGGGGGCTGGGCCAGAGTGG +GGACCATGAGGGCCTGTCTCTCCAATTGAGACACTGGGGTGGGCTTGGAGGGGAGTAGAT +GCCACAGGCTGGAGAGCTCAGACCCTGGCAGGGGCCAGGCCCTGCAGAATTACACTAGGA +CTGCCGAGTGCAGCACATCCAGGATGGGCTTCCAGCCTTGAGCATGGACTCTGGGCCCGA +CATTGGCCACTTCTGCCGCAAACCTCTGTTGTTTTTCTCTGGGCTTTTGATCTTAATTAC +TTATTGAAGAAAGTAGAGAGGCCAGTTACTTCACACACACTCAGACCATCTGTTGCAACC +TGCCAGGGTGGAGCCTGGCTGGCCTCAGCTTGTCTGATGGAGAGATCAGGAGGGTGGGCG +AGGCAGAGACGTTCCCCTGTGGCCCAGGCTGCCTCGCCTGGGGAGGCCAGCCTCATCCCA +GGGCAAGAAGTCTGCGCGGCCAACCCTGAGGGCTACTCCTAGACACTATTTGTTCCAGGT +GGCTGGGGTGGGGCTGTGAAAACCAGAATGTTGGGGGTTTTGGGCGGGGGGGAGGGGCAC +AAGTAAGTTCTGGTCAGCAGGTCACCTCCCGGCCTTCCTTGCTCGTGAAGTCTGTTGGCC +CTCCAGGGGCTGCTGGCCATGTTGGGACAGGCTCAACTCCCTGTTCTTACTGAAGGAAAA +ACAAGCACATCCATTTTGATCTGCTTCGCACACTGGCTTCCACTCAAATGCAGAAAGGGC +TGAGGGGGGCCACAGTCCCACTAAGCTCCAGCCCCAGAGCGTACAGACCCTGGAGTTGAG +CTGGGAGGGCCAGGCCAGGCCCTGGAGGGCAGGTGAGGGGGTGCAGGTGCTCCTTCTGTC +TCTGAAGCTCCTGCTTGTGGTGGGGCTGGGGAGGCCGGCCAGCCTACTCTGCTGCTTCTG +TCTCCCTCAGGCACAGCCTGCATCAGGCCAGGCACCCCAGCAGCGTGGACTGGGGTGACA +CCCACCTGCTGCCTAGCGACCCGGCTCCCTGACCAGCACCTGCCCTTCCTCGAGGCCCAC +CAAGGCCCCCAAATGGGCCATGGGCCACCTAGACCAGTGCCGGCCATGGCCTCTGCTTGA +CCATGACACCTCGTAAGAATTGGTCTTTAGAAGTTAGATTTGCCCTAGATGTCCATCAAC +CTCACAATGACAAAATGAAGTGTGGCTTCATGGAGAATGCTTAGTAGTGAAAAGGAAGGA +GTTCAGAACACTGAGCAGGTAAAACAAATTCCAGAGCCAAAAGAGTCCAAAGTACCTGCA +CACACAAAAACTGGCCTTGTTCTCAGGTGTAGGGGCAGAGGTGCATCCAGTTACAGGTAT +TAAATGGTGTGGGTGGACCCACGCTCCCCTCCCTGGGCAGGACAGTAGTGGCCAGAGAGC +TTTCCATTTCTGTGGCACATGCTGGACTTTTGAAAAGAAGAGATCGCCAGTTTAATGAAG +CTGACTTTAGTAATGCATTTTCCCTGCTTTACTGACTGTGGCATCTGCTCATCTTTGTCC +GGTCTCTTGGTCAACAATTCCCCACTGTCCAGGATCACCAGAGAATGCTCCTCCCAAGGA +CTTGACCAAGCTCAGACCCTTTAGCTGGGCAGTCCTAGGAATGAGTCCCGAGGCAAGGAT +GGGCCCAGTGAAGCCCTGTTTCTATCAGTGAGGAGTTGGGAAATGTCCAAGAAGGGGGCC +ACAAGTCACTCATTCGAAGTGCCATCGAAGAATATTCAGCAACACAGAAAAATAAGTGAA +ACAATATCTAGGAATGTGTGCATATATGTACACACCCATGTATACATGTGTGAACGTAGA +TAGTCATGGCCCAAAAATGGCTGGGATGCTGGTGGTAACTACCTCTGGATGGTTAAATTT +GGGATTGTTTAAATTTTTTCTTTATACTTCCCTGGAGTTTCCAAACTTATAACAAACAAG +CATTGCTTTTATAATAATAATTTTTTATAAAAGTGTTACTTTGAAGGAAACATTCTGTAA +ACTCAAGGAAATTCAGAAGGTGCTCCAAAACTGTTTTGCCTGGCGGCCCATCTGGCCCTG +GCCTGGTGGACAAGCCCTTGTGAACAGGTTTGGTTTTTGTGCAGAATTTAAAAAAAAACA +AAACTTAACACTCTATAATTTGTTTTTTCCCACTCAAAATGTTTTGGACTCTGGCCACAG +ATAATTCCATGTATCTATCTACAAATATAAGTACATATTACATAGATGTACAAACATATG +TCTCTATGTACATCTAGGTGCCCATCAACTGGGGAATAGATATTCCCTTTCCCAGCTGAT +GGGCATCCAGGTAAAATCTCATTTTAAGAAACAGATTTTTTTGAGCTGTTATGATCAAGT +AACACTTTTCTTTGAACAGACAGTGAAGTGAGTTCTATAAAAGCCCGGTCTCCTCCCTCA +TGTGACCTGCACCAAGAACCACCCAGGGGACTGGAGTCACTGAGTCACAGGAGCCTCTGG +AAGGTTCTCATGACCAAGCCCTTGAGACTAAGAATCTGGGTGGCCTAAGCTGGATTGGAT +TAATCACCCAACGCCCCATCATGGGACCACTGACTGCAAAACCCTCAAAGCTCTACACTC +TTGGGGTGTGAGCAGAAACAGACACGTGCTTACCACTGCTAACAGGCATCAGTAAATACT +ATTTAAATACATGCTTGATCATCATAAGACATTAAAGATGTTAAAGAAGTACTTACGTTC +CATGTATTCGTTTTTAAACTATCCATCTCTTTCTGAATGCATGAGAGAGAGGGAAAGTGA +GAGTTACCATCAGTGTGCAGGGCCACCCCATCAGCACCGCACCCTCAGCGGGACAGGGCA +GCAGGTGCAAACCCACGTATGTCCCACGGAGGACTGCTGGGGAGCTCCTGGAATCCTAGG +CCCCCAGTGGGGAGCTGTCTTCCATCTCCCAGCAGGGCCTCCTGAAAACACCACTGTTTT +CTTGCTTGGGCCAGTGCTCCAAGCTCCCTAACCATCCAACCCTGTTACCTCAAGAGAGCG +GCCAGGCTGGGGTGCTACTCCCAGATCACCCCCTTGGCCTCTGTGGGGTGGGGACAAGAG +GCTGGTCTGATGCTGTGGGGCTCAGCAGCCACCAACCTGGATGTGCCTTGGCTCTTCCCA +GTGGCGAGCCAGGTGACACTGGTCGCGCCCTCAAAGAAGGGAAGTTGTTGTGGCTTACAA +GGATCTAGGGTAGAGGTCCTGAGGACAGATATTTCCCCCTGGCCCTTCCTGTCACTGCAA +CTAGCTTAAGTTGAAGGCAAATTAACTGCTGTGGCAGATGCCGTAGGTAATGATCTTTCT +CCTACAGCTAGGACTGTCGTGAGAAGACTGATCACCTTGGTATAAGCAAGGGCCAGGTTT +ATTCACCAGGGCTGGGTTTATTACATCAACTCAGGAGTCTGGGGAGGCTGTTGGCAGCCT +GGGCTCCAGCACTCAGCCTGTCACTGGGGCACCTCCCACCTGCTCACTCCCACCCCAAGC +CTCTAACGGAGCCAGCTGGTGCCAGGACCACCATGGCTTCAGAGCTTCGTGGATGTGATT +ACAAAATATGGAGCTGATTCTACTCTGCGACAAACCAGGTGCCCTCTGGGCAGTGGCCTC +GCCCTGAGGAAGGCCTGGAGGGGTGGTGAGACATCCACCCAGTGACTGAGTTGCTCGGGC +CCATCCTGGAAAGTGCCCCCACTGCCATCTCCTGCAGCACTCCTCTGTGTCCTCCCGGCA +TCCCCATGCATGTGGCCCACTCTGACCTCAGGGCTGGCTGCCTCGGGGCCAGCCCATCTC +CCAAACTCACATCCAGGTGGCCTTCCTGCAACTAATGGGGCAGCGGGCACATCCCCAGAG +GGGCCATTCTCTGCACACAGTGCTGGCCGCTGGCCATCATGTCTTCCATGATGGGACTCC +TGGCTTGTCCCTGCCTGTACCCGCTGCCCGGGCCTCACCCGGACACCTGCTCCCAGCCTC +TTTTCCCGAGGATCCCACTGCTTCCCTGGCCCATCTCTGTGCTCTCTCCTTGGGGCACGG +TCTTTTCTAATCCTGGCCATGGCCCCTCCTCCCTCCCAGACTCTGGGGACCCTTCTGGGG +ACAAGGACAGTGCAGCTGGGGGTATGCCCTGAGGCCTTGTTGGTCATCCTTTCTGTCCTC +TGTTGAAGTCACAGAGTAGCCAGGGGCCCCAAGAGGAGGGAGGAGAGAGTGAGACCCCTG +CCACATAGGTAGCAATTCTGACAGCTCCCTTCTCTGAGTCCTCATCTCCCTGACAGTCAC +CAGGCCGACGCAGCCTAACGTTTCACTCTGGTATGCTCTAGACCACTCAGGGCACTGGAC +CAGCCCCAGCGCTTCTGGAATGCACCTGTTCATGCCTGCCACTTACTGGCCAAGCCGCCT +TATCAATGTGGGCAGGAATCCTGAACCTCTTCTCTGCAAAGGGACCTGAGAAAGTACCAC +TGAGGCATCTGTAGGCATCGCCTGGCTCCATGGGGGGCCTGTGGGAAGGCACCACTGAGG +CACCGAGGGCATTTCCAGACCCCAGGTAACCAGACAGCTGTGTTGTAAAGGCACGTGGAA +TTATCCCAGATAACAGAAGAGACATGGATAGTTTCTGGTGAAGCTGCCTCATCTAACATG +CGAAGGACCTCAGAGCACAGGGAGTTGATAGCACCACCTTGTCCTGTCCAGCAAGGGTGG +CCCAACACACAAGGTCAACTAATTCCCACGACGGCCGTGGCCTTTCAAGAGTCTGAAACA +AAGGGAAATGTCACAGAGCAGCTGGAACACACACATGCGTGCCAACAGGCCACTGTGGCT +GCTAGGAACGGGGGCCCTCTCCAGAGCCCTGGGCCCCTCAAAGAGGACCAAGGGCGCCTT +CTGCTGCTGCCCTCTGATCCCAGTGGTTCCAAGGGCTCTGATTTCTAACACTGTAGTTAA +AACATAAAAGGCCATCCCAAATCCAAATATCTAAATGCTGCCTAAAGTATGGGGGAACCA +TTATTAGCTTTGAAAATGACACGGGTCTAAACTTGACATGGAAGATAGTCCTGGCAGAGG +TGAAGGCAGGGCCCTGACAGGGTAAAGACTGCACTTTGGTTAAAAAATTATATCGATCTG +TTTCTGTGTGTGCACACTAATGTACAAGTGCATGATTTGTATCTGCATGTAGACACAACC +CATCGCCATTCATCGCTATTGATCCTTACGTTTGTATGCCAGATGCGCTATGTGCTGGCA +CACGGGTGGTGGGGTTATTTTTTCACCCATCTGTATTCTGAGTGATCCATGAGGAACTTG +GGTTCATCAGTTCAGACGAGCAGAGCTCGGCTGCATGCTAACTTTACTTCACCAGCTCCA +GACGGCTTTCCTCCCCTTGTCAATACACATGCTGCTCCACTTGCCACGGGGCTGCATCCC +AATAAACCCACTGTGAGTTGAAACGATCCTAAGTCAACAATGTGTGTGTGTGTGTGTATG +GTTGTGTATGTGTGGATGTGATTGGTGTGGTGTGGGTAGCGTGCATGTGTCTATGTGGTG +TGTATGTGCTTTGGTGTGTGCAGTATGTGTGGTGGTGTGTGTGTAACAGTGGTATGATTG +GTGTGTGTGTGATGTGTGTTGTATGCTGTGCTGTGTGTGGTGCATGTGTGAGTGGTTGTG +TTTGGTATGGTGTGTATGGGGGTGGTTTTAGGTGTGTGTACAGTGTGTGTGTGTGGTGTG +TGTTGGTATGTGTGCACATGTGCAGTGAGTATGCATGGTCTGTGTGTATGGTGTTTGATG +TGTGTGTGGTGTGTGTGATTTGGTGTATGTGATGTTTTGTGCTGTGCATTTATTGTGTGC +ATGCACATGGTGTGTGTGTTGTGTGGTGGACATGATTGTGTTTGTGATGTGTGTGCGTGT +TATGTCGTGTGTGTGTGTTGTGGTACATGTGTCGTGTGGTGTATATTGTGGTGTATCTGT +ACGTATGTGGTGTATCTGATATATGCGTGGCGTGTGGTGTGTGTGGTGTGTTTGTGGTGT +GTGGCTGGTGTGTGGTGTGTGGTATGTAGGTGTGTGTCTGGTTTGTGTGTGTGGTGTGTA +TGAAGGAGGTATGGTGTGTGTGTGATGCTGGCATGTGGTGTGTGTGGCATGTGGTGTGAG +GGGGTGTGGTGCTGGTGTGTGGTATGTCTGCTGTGTGGTCTGTGTAGTGTGTGTGGTATG +TGTGTCTGGGATGTGTGTGGGGGGGTACAGTGCATGGCATGTGTGCGGTATACGTCATGC +TCATGTGTGGTGTGTGTGTCTGGTGTGTGGTATGTGGCTAGCATAGTCTATGTAGTTTGT +GGGGTGTGGTGTGTGTGTGGGGTGTGGTTGTGAGGGGTGTGATGTGTGTGTGGGGTGGGG +TGTATGTGTGGGGTGTGGCATGTGTGTGGGTGTGGTGTGTGTCTGGGGTGCGGTGTGTCG +GGCGTGTGTGTGTGGGATGTGGCGTGTGGGGTGTGTGTCTGGGATGTGTGGCATGTGACT +GGGATGGTGTGTGTTGGGGGGGTGTTGTGTGTCTGGGGTATGGTGTGTATCTGGGGTAGG +GTGTGTATCTGGGGTGAGCTGTGTCAGGGGTATGTCGGGGTGTGGGGTGTGTGGTATCTG +GGGTGGGGTGTGGTGTGTGTCAGGGGTATGTGTATGTCTGGGGTGTGGGGTGTGTGTTAT +GTCTGGGGTGTATAAGGTGTGTGTGGGGGGGTGTGGTGTGTATGTCTGGGGTGTGGGGTG +TGTGTTATGTCTGGGGTGTATAAGGTGTGTGTGGGGGGGGTGTGGTGTGTATCTGGGGTG +TGGTGTGTGGGGTGTGGTGTGTGTCTGGGGTAGGGTGCGTATGTGGGGTGGGCTGTGGCA +TGTGTGTGGGGTGTGGTGTGTGACGGTGTGTGTGTCTGGGGTGTGGTGTGTGTGGGGTTG +GTGTGTGTCTGGAGTGTGGTGTGTGTTGGGGTGTGTGTGTCTGGGGTGTGGCATGTGTGT +CTGGGGTGTGGTGTGTGTCTGGGGTGTGGTGTGTGTCTGGGGTGTGTGTGTGGGGTGTGG +TGTGTGTCTGGGGTGTGTGTGTGGGGTGTGATGTGTGTGGGATGTGTCTGGGGTGTAGTG +TGTGTGTGTCTGGGGTGTGGTGTGTGTGTGGGGGTGTGTTTGGGGTGTGGTGTGTGGGGG +GGGGTGTGTGTCTGGGGTGTGGTGTGTGTCTGGGGTGTGGTGTGTGTCGGGTGTGTGTGT +GGGGTGTGATGTGTGTGGGATGTGTCTGGGGTGTGGTGTGTGTCTGGGGTGTGTGTGTGG +GGTGTGATGTGTGTGGGATGTGTCTGGGGTGTGGTGTGTGTCTGGGGTGTGGTGTGTGTC +GGGTGTGGTGTGTGTGTGGGGGGTGTGGTGTGTGTCGGGGTGTGTTTGGGGTGTGTGTGT +GGGGGGTGTGTGTGTCTGGGGTGTGGTGTGTGTTGGGGGTGTGGTGTCTGAGGTGTGTGT +GGGGGGGTGTGATGTGTGTGGTGTCTGGGGTGTGGTATGTGTGTGGTGTGTGGGGTGTGG +TGTGTGTGGGGTGTGGTGTGTGTGGGGTGTGGTGTGTGTGGGGTGTGGTGTGTGTCTGGG +GTGTGGTGTGTGTCTGGGGTGTGGTGTGTGTCTGGGGTGTGGTGTGTGTTGGGGTGTGTG +TGTCGGGTGTGGTGTGTTGGGGGCGTGGTGTGTGTCGGGTGTGTGTGTGGGGGGTGTGAT +GGGTGTGGTGTGTGGGGTGTGTGTGTTGGGGGGCGTGGTGTGTGTCGGGTGTGTGTGTGG +GGGGTGTGATGGGTGTGGTGTGTGTGGGGGGTGTGGTGTGTGTCTGGGGGGTGTGGTGTG +TGTCTGGGGTGTGGTGTGTCTGGGCTGTGGTGGGTGTGTGGGGTGTGGTGTGTGTCGGGG +GTGTGTATGGGGTGTGGTGTGGGTCGGGGGTGTGGTGTCTGAGGTGTGTGTGGGGGGGTG +TGGTGTGGTGTGTGTCTGGGATGTGGTGTCTGGGGTGTGGTGTGTCGGGGGTGTGTGTGT +GTCTGGGGTGTGGTGTGTGTGTCCCTGCCCGTCCTTCACGGCTGGTACCAGGGTGACTGA +CTATAGTAAATGTGCATTGCTAGCCGCATGACAAAGCTTAGACAGCAGTCCATCCCAGGG +CCAACGCGGTGCAGGATGGCTGTGCAACAGCTCTGAACACTCTCAAGGCCGCTGTCCCTC +CTGTGCGGCCACAGTGCACACTGAGGCAGTCGGCCACTCCCAGCTGCTCCAGGCCCTGCC +GATGCACTCAGTCCCCCAGGACTCAGGATCATAGGGCTAGCGGCTCCCAGGGCACGGGCC +CCAAGGCAGTGCAGTCCTGACCTGCCCACCCCTCTTGTCACTGAGCCCAGGGTACCATGC +TTGGGGTGACACCATGTGCTGTCTCACCTGGGCACTGCAAAGGCATAGTTCCCACTATGA +CACCCCTAGGGTGTCCCAGGGCCTTCTCAGGACCGTCCCATCCTGCCCCAGGGACAAGGC +TGGCCTGTGCCAGGGCCATCAGTGGATCTTTCCGTATCATCTTCCACTGATAATTCCACT +TCCTAGAGGCGAGAACTGTGGTGGAGAAGGGATGAAATGTGTCTAGGTGGAGAGTGGCAC +TGGTGGCCAATCTCCCACCCCAGCTCCTGACACAGGCCCACAGGTGTGGCCCTGTCCCTC +CCTTGGATGGGCACTGAGGCCCCTGGGTGCAGGACAAGGGTGGGCCTCCACCCCACCACC +AGGCCTCAAGCTCTCGCATCCCCAGGACACAGGCCTCTCCGCCCTACTCCGCCCACGTGG +CCACATCACCTCCACCGCACCCCACGTTGGGCCCTTGTGCCCTGGCAGCCTCTGCACACA +CCACAGGCTATGTTTTCCCCTGTGCAGACCCACCCCGATCCCCTTTCAGGAAGCGCTTTG +GCCTCAGAGGGCCCTCACCTCTCCTGGATGGCCAAGTCCCTGGGGCCACTTTCTGAGCAC +TGGCCAAGTGTTGGGGCAGGTGGGGACATCTCCTGGGTGACACATGGGCCTCCACCAGCT +CTGGGGCAGACCCAGTCCCCAAGTGCAACCCTGACCAGCTGACCTTCCATCAGTCAGCCC +TCTCTGGGGGGTGAGACGCTCCCCAAGACACAGGGTCACCCAGCAGAGCTACAGGCACCA +GGACGCAGCATGGGGAACTGAAGATGCCACGAATGTCCTCTTAAGTTTCATATTCTAAAG +ACACTTTGCTAGCCCTTTAATCAGACAGCCCCCAAACCACTGTGACAGCTACCACGAAAA +CAGCCATTATAGCAAAGAAAAACCCAGCCAAGTTCCAAAGCAGCCCTGCCCTGGGTGGCT +GGGGGAGGACACAGGCAGAAGCGGTAGGCCTGTGCCTTGAGTGCACTGTATTGCAATCTC +CAGGCTCTGGGCCTCACCTGGAATGGCTCATTCCTGGCCCACAAGGCAGAAAATGGCACT +CACTCTCCTCAGGAAAGTCTCTGGGACTTGCAAGTCACACTGTGGCCTCTGTCGCAGGAA +GCATCTACAGACCCCAACAGAACCCTGGAGCCTACTCGGGAAATTCACAGCCACAGCCCC +TCTGAGTTCACGGCATGCCCATGATGCCCTGGCCTCGGCCCACCCTTGAAAAGGCTGAAG +CCACTCTCTCCTAAGCTGGTGCTCCCTGGGGAGGTCTCACAGCCTTCGCAGGCTGTGGCC +TCAGTGGAACAAGTGAACGAGAATGTCCCAGATGGGGCCAAATGCCTCTGGAGAGAAAGT +AAAGACCACGTGAAAAGGGGGTGGCGGAGGGCTGGGGGCCTCAGTTCTCAATCTGTTCAG +TCCATCCTGAGCACTGGCAAAGGACTGCCCTCCTCCCTCAGCTCCCCTACCCTCTACACA +CTACTCCTGGCCACACTGCTGCAAGCCCACAGCTACATTCCCCATATCCATCTGTGACCG +CCAGCTTTCTGTTAGGTCTGGCCATGGGAGTCATTGACAGGAGACAGGAAGTTGGAAGGA +AGAAACATTTTTGTGGCTTCAAGTAGGACCTCCAGCAGTGAAGGCAGTGTGGCGGGCAGG +GAGAGGCTGCAGATCACACGGCCACAGCCTCGGTGGCACAGCAAGTGAGACTGAGTGTTT +GACACTTCACTCTTCCTGCCCATGGCTGATAATGGAAACCTCACCTTCCCACTGTTCCCA +GCCCTTCTATCACCTTTGTAACCAATTCCCTGTGTTAAATGCCCTGTGGTTGAAATATCT +GGGGTGGTTTCTGTTGCTGTAACAGTGATGTCCCTTCTCCCTGGGCACCCATCTTTCATT +CCCTGCTGACCCCAGGGGCTTGTGTGTATGCCTGCCTAGCTACAGGGGGTACACCTGGAG +CCTCACATTTAAAAATGTAACAGCAGCCGGGCATGGTGGCTCATGCCTGTAATCCCAGCA +CTTTGGGAGGCCAAGGCAGGTGGATCCCCTGAGGTCAGTAGTTTGAGACCAGCCTGGCCA +AGATGGCGAAACCCTGTCTCTACTAAAAATACAAAAATTAGCTGGGCATGGTGAGGTGTG +CCTGTAATCCCAGCTACTAGGGGGGCTGATGCAGGAGGATCGCTTGATCCTGGGAGGCGA +AGCTTGCAGTGAGCCAAGATCGTGCCACTGCACTCCAGCCTGGGCAACAGAGCAAGACTC +TGCCTCAAAAATAAATAAATAAATAACCAACCAACATTGCCTGACCATACAGCCTGCCTG +CATCTGCCCGCAAAGGAGCCCTGGGTCCACGGCCAGTTCATAGAGACCCGCCCGCTTCCC +AGCCTCCCCACCGAGGAGGAGCTTCCTGAGTCTGCCTGAAGGACCCCAGTGCTGCGACAG +GACACAGTCTCCATGGAGACATGAAGTCCTCTGGGATGCCTGCACCAAGGCAAACTAGCT +GGCCGAGGAGCACCATTCAGCTGTGAGAGCGGCCACAGGGGGCTCAGCACAGCCTTGGTC +CGTAGCACCCAGTGGAGGGCAGGAACCACACAAGCCAGCCTAGCAAAGCTCCGTCTCCAC +AGTGCTCCATGCTCACCGGCAGCTTCTCCTGTCCAGTGCTGGCTGCCAAGGGACATTCTG +GCCTCAGCAGACATGGGCCACCTGGGGCTCTCAGAGCTTGTTTAACAGGAGAGGGCAGCA +CCTTAAAACTCTCAGGAGCTACTGACAGTGTGTTTAACATGTTTAAAAAGAGAGCAATTG +GGTTTGCTTTTCCTCTTCATTAACTTCATCCCTCCCCCGGGGCAGGCTCTAACAGGCCAC +TTCCTTTCTTTCTGTATCTACTGATCAGTCAGATGACAACACAGGGGCCACCAGGGCTAC +CACGCACTGCCTGAAGCACAGGATACATCTTTGAAGTGTGGTTCTGGACATCTACTATCT +TTCAAGAGCAGATATCCCATCCGAGTATTTTCCAATCCAGGGCAAATGCCTCCAGGTCCC +AGAGGAGTACACTAGACTCTCAATCTTTTCTGTTTTTATAATGATGATGATTTTTGAGAC +AGGGTCTTGTTCTGTGATCTAGGCTGGAGTGCAGTGGCACCATCATACCTTACTGTAACC +TCAAACTCCTGGGCTCAAACAATCCTCAAGGCACGTGCCACCAAGCCTGGTTAGTTTTTT +TCACATTTTTGGGTAGAGATCAGGTCTCGCTATGTTGCTCAAGCTGCTGTGAAACTCCTG +GCTTCAAGCAATCCTCCTGCCTTGGCCTCCCAAAGCAGGGGGATTATGCCCGCCAATCTT +TTCCGCTTTTAAATACCACGAAGCAAGTCATTAAAACAACTCCCATTCTGGAAGCTCTTA +ATTTTTTAAAATTTCCAAATACCACGTATATCAACCTCCAAATTGTTAGCAGAAATAGAA +GCACTCTGGCTCTGGAGGCTGAGGCAGGAGGATGGCTTAAGCCCAGGAGGCAGGGGCTGC +AGTGAGCTATGATTGTGTCACTGCACTCCAGCCTTGGTGACAGAGGGAGACCCTGTCTCT +TGAAATTTTTTTTTTTTTTAAGGGAGAAGCAATCCTATATACCACAGGTTGGGAAACTGG +GGCCTTTGGGGCAAATCTGGCCCACCGTGCATTTTTATAAATAAAGTTTTACTGGCACAC +AGCCCTGACCACTCGTTGTGTATTGACTATGGCTGGTTTTACAATACAACAGCAGAGCTT +AGTGGCTGTGACACAGCCTGCAGCCCACAAGGCCTAAATATCTAGCCCTTTACAGAAAAC +ACTGGTTGACCCCTGTACACTAGAAGTGGCTTCACACTGTCTACAGTTTCCCTCGGGATG +GACCCACAATGAAAGCGTGAAACGGCTCAACCCGAGGGACGCAGCCAGGACAGATAAGGA +AGGTAAAGGAACATGTGGAGGGATGTGGAGGATGCCCCCGCCCGCCCCCCACCTGTGGGA +GGAGACAGATGGACAGGGCACAGGGGACAGAGAGGGCCCAACTCACCTGTGGCCTGGCAG +AAGAGGTAGAAGTTCCCCAGGGCGTGCACGTGCTGTGCCTGGTCACTCAGGAAGGGCGGC +AGCAAGGAGACCCTCGAGCTGCTGTCGGGCCCCGCACCCGAGGCTGGCCAGGGGGTCCAG +GGAGAGGAAAGCCTCCTGTCCCCCACATGGCCCAGACAGGACAGGGAAGAGGAGCCAGGA +GGAGGGAGGGGCTTAGGAGACGAGGCTGTGAGACAGAGAGGACAGAAAAGAGAGGGCACT +GAGGAAGAAGTCGCCAGGAGCACGTCACAGGCCAGAGAGGGCAAAACACAGCAGGAAACG +GACAGAAAAGAGCGAGCCCAGCTGTCCCGCCTGGGCCATGCAGGGGCGGGAGGCTGCACA +GCCTCCGCTAAGGAATGTCTTCCCCAAATCAAGGATAGAAGCTTCTCATTTATTTGGGTA +CTTTCCAAATGTATACAATTCAAAGTAGAAAAATAAAAACAAGGTAAATCTTATAAAACA +CAAATGTTTACACCAAAATGGTCAAATCCTATCATGCTGGAAGATAAGACTGTCCACACA +CGCGCACAAACATCCAGAGTTTATTGCTCTTCACCATGGAAAAAAAGTCTCTTCCCGATG +GGTATTTACAAAGCGGGGAGATGGAGTGTGAAATTAACCAGTGTTGAAATCGTACCACCC +ATTCACATCTTCAGGACAGTGGCAGGAACAGCGCCGTATGCTTGAGGGTGCTGTGGTCAC +AGCTCGCGGCCCCGGCCACCGAGGCCCAGTTCCCTTCCAGTAGTGGGCAGCTCAGTGAGG +CTGGATAGAAAGTCTGGGCAGGCAGTGGGTAAGCAATTGAAGCAAGAAGAGAAAGGAGAT +GTTCAGAGAACCAAAGGCGCCCTTGTGAAGGTTCCATCTGTCTCACAGGAGGTTCTGACC +GACAGCTGTGGGCTCCAGATTGTACCGCACTCCCATCTCAGCTCTGGGCCAGCCTGGCTC +CACTCAGCTCATCCAGGCTACCTTCCCTTGCTCAAAACCCACCTCGTGGATGTGGGAAGG +TCCTCTTCTTCGAGAGAGTAAAAGTTAAAAAAAAAGAAAAGTAAAACGAAGTACAGAAAG +AAAATCTCTCCAAAAACAATGCTTCCCTCAAGGAATAAAGTTAAAAAAAAAAAAAGAAAA +AGAAAAAAGGTGAGTGGGCTCCGGGGAGTGTTTATGTCTACATTTCTAAAAGCAGAAAGA +ATGCATTTAGCAAAAGGAAGTTTATCCCTGAGAATCTTAAGCAACGTAAGCCGTATTTTA +TGCCAAATATATAACAAAATCTGGAAGATATACATCTTCTTCTAAATATTAACACAACTG +CTTCTGTAACTAAAAAAAAATGACCCATGACATAAACACAATCAAAGCAAAATCCTAAAA +AAATAATTAAGTGGAAGAAAAGGTTCGTGCCAATCTGGACAACAGGCGATAAGTTACCAA +TCTGATAAACTAAAATGTCATTTCCAATCTGGAATTAAATAATCTTTTAGTGGCTGCTAC +GGGGAGGGGAAGCTGAAGGGATGCTCTTCTCAGCCAACAGAGGTCCAGCCACCTTTCCCC +CACTACAGAAAGGGCTCAGGAACTCCGTGCCGCCCGTGGGCCTTCTTCAAGTACTCCGAC +TGACTTCGGAACACAAGACTGGGATGCAATGCTTGTCATTTTTCCAAAAGGACAAAGAGA +AACCAAGTCACAGGCTCAACCCAAGAGAAAATAGACAAGAGGACTGAGGTTGTCTGCACG +ATGCGGGCTAACCTACGCAGCACTGCACGAGACTCGGATACTGAACAGGAGAAACACAAA +ACTCTCCACGCCTGGACACGTCGCAGCCGAGGCACCAGCGGGGATGCACAGCCGGCCTCA +GTCTCCATCTGCGTCTGAGTCAGCGAACTTCAGCTCACACTTGACGTCAAAGGGCTTGTC +CCTGGCAGAAAGGTCGTCGATCCTCTGTGAGTCCTCCCTATCCGTGGGGACTTTGCTGGT +GATGGTGTCTTGCTCGGTCTCATAGCCGGTGTCCAGGGCTGGCTTGGGGTGCTCCCCATT +CTGCTGGGAGAAGCTCCCTGGCTCTACTAACGTCTCCTTCAGGCTCTGCTCACGGTCACA +GAAATCTGACTTGGGCTTCTTCTTCCCAATTAGTAGGGCCGAGCGGAATTTCAAGCACTG +TCTGGGCAGGTATCCCTTATAGCAGTTGTAGAAAAAGAGGCAGAGGAAGAGAACAAAGAA +GAAGAGGAAGAGGGACATGAGGAGGCGGTTGTCGCTGGACTTAAGATACATGGTTTTCTC +CGAGTGGAGCTGGGGGACCGTGTTGATGACGATCTTTGGTTCGCAGGATGTGCCGGTGGG +CGCAGGCTTGGGAGGAAGGGTGATGGCCCCGGAGGAGGTGGCCTGCACGGCTGGGGTTGG +GGGAGAAGACCCTTGGGTGGATGCCACCAACACTTTGGTGGCAATCCTACTACCTTCTGT +CTGAACAACTGACAAGGTGGGGGCCACTACGGGCTTTGGAACCACCTTCACTTCCAGGAC +GTGCTTGGCGACCACTTGGAAGACCGTTTTGTTCTTAACCCTCTCCTCTGACAGGCACTG +GTACACCCCACTGTCTCCTTCTGACAAGTTGAAGATGAGCAAGTTTTTTCTGCCCATAAG +ACCGTACTTGGGGCTCTCGGCCTTCAACACGCCATTCTGGAACTTCCAAAAGACCCGGGC +CAGGTTGGATTTTTGGGAGCATTTCAGTTCCGCTGTGCCACCGTGCTTGAAAAAATGCTG +CCGGTAACTTCCTTTACTTTTATCTGGAACATCAAAATAAACGTGCACAGCGTCAACAAT +CCCCATTTGCTATTTAACAACTTCTTTAAAATACCCACAAGATGACGCAAGAGTTTCACC +CACTGTAGCAACATGGAATCTTCCAGAACAACTAAGGAGATAAAGACATGCGTGACCAAA +AAGCAAAGATGAGCCCTGGATGACAGCCCATGGGGACAAAGAAATTGGAGGCAGCTCTGA +GCAGCAGAAATCCCATTTCTCACCCGTGTCCCAGAAGAAAACGCGTCAGGCTGGGGAAGC +TGAGCAGAGGCCAGTTCTGTGCCTAGTGTCAGCTCTTTGAATCAGACACGAGACGCTTCT +GCTAATGGCTGCAAGGAAGACTGGCCTTTCAGTGCATCTCAGCACTCTCCTCCTGCCTAA +ACTTTTCTTTTTTTTCTTTTTTTTGAAACAGGGTCTGGCTCTGTTGCCCAGGCTGGAGTG +CAGTGGTGCAATCACAGCTCACTGCAGCTTCAACCCCCCCAGCTCAAGGGATCTTCCCAC +CTCAGTCTCCAGAGTAGCTGGGACTACAGGTGACCACCTCCAGGCCTGGCTAATTTTTGT +ATTTTTTGTAGAGACAGGGTCTCACCACGTTGCCCAGGGTAGTCTCGAACTCCTGAGCTC +AAGTGATCCTCTTGCCTCAGACTCCCAAAATGCTGGGATTACAGGCATGAGCCACTGTGC +CCGGCCAGCTTTTGTTTTCTTTTTAGAGTCTGGGTCTCACTTTGTCACCCCAGGCTGGAG +TGCAGTGGCATGATAAGCTCACTGAGCCTTGAACCCCTGGGCACAAGCAATCCTCCTGCC +TCAGCCTCCCTAGTAGCTGGGACTACAGGCGTGTACCACCATGCCCAGCTGCCTAAACCT +TTCTTAGTCTGATGACAGCTGTCTTGTCAGGGTCAGGAAGACACAGAACTGAGGGTCAAG +TCTGCCTTTAGCACCCTGGAAGGTGGCTGCTGGGGAAGGGGCATCTGGCCTGATGCCACC +CCTCCCTCTGGGTGTGGTGCTATTTCAGACATCCACAGGCGGGTGAATCCCAGGTGGGAG +CCCCAGGGGAAACACCACCCCAGCCCTTACACTGCCTGAGGATTAATCACTCATGGGCTC +CTTTCTCCCCATTTATAACAGGCTTAGGTTTTGCTTAATGAGCCCCAAGCTAAGCAGAAA +GAAAACAGGATGGTTTTGGAAGGAGACTGCTTCCCAGTAAGCAGATACACTCTAAGTGGC +TTCAAGTACTCTTTCGGCAAGAAAAAAAGACAGAGAAGACCACGAGTCTGCTACAGAACA +CTTGACCTCTGTTCCGAGTGGAGAAAGAAAAACAAAACACACACAAATGCCACAGAACTG +AAGCACCGTGAAATGGCTACAAGACCTCGCCACTCCCAAAGGAAATGGGACGTCGAGGAG +TCACTCACCCGGGCACACAGAAGCATCGCCGCTCATCTCCTGAATCAAACCCCTGCAAAA +CAACCGGCACGTGTTATTCACCCACACACATGGGGGACATCCCCAGGCAGCGCATCCCGC +CCCATACCTGCTGGGGCTCTCGGTCTGGTGCAGAGCCACGCAGGTCGCTGTGGGCGGGCT +CCAGGCGCAGTAGGGGTCCCGCGCCAGCACACAGTCCTCGCAGGTGCCGTGCTTCCCACA +GAAGGCCAGCGGGGCCTGGACCACGCCCGAGTTAGAGCCAGCATAGACAAACCTGTTGCC +CTGCGTGTATGAGACAGAGAAGAACTAGCATCAGGCAAGCAGGCATCCAGGAGCATGGCC +TCTGCTTCTGCACCAGTGTGTGGGAAGCAGCCAGAGTGTACCTTCAGGGGACATTGCAGT +AAGGAGGAGAGGTACTCAGAACCAGAGGCAAACAAGGCAGGTCTGTGACCTTCCTGCAGA +ATCCACGTGCTATGTCAGGGCTCACTGGGCCTTAGGTCCAAATCCCTCTCTCCCCTGTCT +GGGCACCCACAGGTGCCTGCCCTCCAGCAAAGCGCTTCTCTGCACGTGTTTCTCTTAGCC +AGTGGGGAGGCTGTTCAGTCCCCACCTCCAGATCTCCTCCCTGCAGCAGAGGATGCATGA +GCCTGGCACTCCCGGTCATCTTCCCGGCCTCACTATAGGTGAGAAGGGGCTGCAGCCAGA +GGCTGAAGCACACCACCTCGAAGCCCAACCTCGTCCCCCGAGCCAGAATGTGAGCACCTG +TGGGCGGGGAGCCTCTCGTGAGGGTCTGGATCCAGCAGAGGCCTAACATAACAGGGATGC +CAAACGGACGACATGCAAAGGATGAGGAGATCGTGATACAAAACATAAAAAAGGAACAAT +GCCTTTTGCTTTTCACTTATCTATATGTAAAAGGGAAGAGCTCACAGACGGGAAGTCAAC +CTCCGAGCTCCAGAGCAGCCACACCCACAGCAGAGGGCAGGTGAGACTCTCCCACCTTCT +GGGACACTTGGTTCCCAGTGACACCAGCTTCAGGTCCATCCCATCAGCCCACCTGGCACC +AGCAGTGCCCAGCACACAGGCATCCAGGGCTGCTGACTGCTTTTGAACGGAACTCAGCTG +GAAGGAGGGTGCCCCACATGCAGTGCACCCACCTGAAGCTCGGGGGCGTGCAACAGACCT +GGAGGTGGCCCGTGGAGCGCGCTCTCTAGCCTCTGCCCAGGGCATCTGCCTCAACAGCCT +GGGGACACCTTTTGGTTAACAATACAAGATTCCCAAATTTACACATGACTTAGTGGTTTA +CAGTCAGATGAAACACGACCTTCATCCTCAGAGGATACGCTCGGAGTCAACTTCAGAGTG +TGGTTGGAAGATCACAGGCCCTGATGCCAATACAGGAAGCCCCAGGCCACACATCCAGCT +GTGCGGACACAGACCCACGAGAGAAAGGGAAAGCCCCCAAGGATGGAAACTGTGATAATA +CACAGCAGAGGGAACCTGGCCCGCCGCTGGCCTCACAGCAGCAGCAGCAGCAGAGACCTG +GGCAGATGAGGCCATGTGTGAGCCACGTTTGTGGGAAGGATTGAGGATGACATCCCAGAT +CACAGTTCGGGCATCGCGCGGCTTGTGGAGGTGGCGGAAACATTCTCTGGCAGCAAAGCC +AAGCTGGGTAACTTCCAAGGGACAGCTGGTCCTGTTGGGTCCCGCGGGGGGCACCTGCGA +GGTGGCGTGAACACCATGCAGTGCAGAGCAGGGTGCCCTGGGTGGCCAAGTGGGGCCCGC +CTGACTCCTCACCCCAAAGAGAGGCTTGAGGGTAGCTGTGGAGGGTGGGGTGGGCTCTGG +GGGGCAAGGCCTGTCCCAAGGGGATCCAGACCACCTCCTGCACCCTGCGGGAGACTCAGC +CCCAGCTTCCGCTTCTCCCGGATGGGGCTGGGCTGCAGCCCAAATGAAACTAAGCTGTAA +AAACTAAACGACGCCACACAGAGACCAAGGGATGACTGTGGAAGGGAAGAGGGGACAGGG +AAGGAGGAACTGGTCGTCAGGACAGCCAGCTGTAACTGCTGCAGGCAGGACCCACTGGTC +GATGTGGATGTCAGTGGGTGGGAGAACAGGGCATTTCTGTAGCCTCCAAGTCTGTCCCTG +CAAATAAGCATGAATGACTGTGGGGGTTTCCCACATGACTCCCCTGGGAGGTGGGGCTCA +CTCTCCCCCACCCCCAGTGTGGACTACATGCCCCGACACACTCGACATGGAAAAAGACGG +TGGTGACTTGGACAGAATGACCAAGGTCATCACGCTGGTGCGAGTCATACAGATGCCCCA +TCCCCAGAAAGCGCCCTCTTTGGTGCTCCCCCTAAAACCACGACCCCAAGATAATCACAA +GAATACACCAGACACACCACAAAACACCAGACTACTCCTCTCCAGGAGTGCTGAGGTCAG +GGAGGCAGGAACAGAGCAGAAGCCGAGGAGATGCAGTGTCCAGTGCAACCTGAGGTGCTG +AGCCAGGAATGTGGTGGGCGGGAGGTAGGAGGGTCCAGGGTCTGGGGTTCAGGTAACGCA +CTGCACCATGACAGCACCTTGGCTCAGATAAATGCACACTGGCTATGTGAGACATCGGAC +ATGTGGAGCTAGGTGGGGGCGCTCAAGATCCTTCTGTGCAATCATCAAAACTCTTCTGTA +AATTTAAAATTATTTCAAGACAAAATTTTTAAAGGCAAAGAAAAAAAGCCTGACCAGGCA +CCTGGCAGCATGAGTGAGGCCCGCTGAGAGCAAGCCTGTCCTGTGCACTCCTGCCCCTCG +ACGCCCCCTGTCTCCGCCTTCCCTGGGCCTGAGGATTGTCCCCTTGCAGGCAGCTCTCAT +GCTCCCATCTCTGTCTCTGCTGCTGTGTGTGCGCGTCAGACCCCGAGGGCAGGTTGGAGT +GACGGTGGACGTGATCAGAGGCAACTGAGCTGTCTAAGTGCCTTCCTTGCCCTCTGCCAC +GCTAGCTGTAGCTCAGCATCCCAAGGAGTCCTGGTGAAAATACAGACACAGCCTACTCGG +TGGGCTCAGAGAGGGCCGAGCAAACCGCATCTGCTGTGTGCGCCCAAGGAATGGAAAGCA +AGGACTTGAGGTATCTGCACACCCACGTTCACAGCAGCACTGTTCACAGAAGCCAGAAGG +TGGGAGCAACCGTGTCCATCAAGGGATGAACGCACACACAAAATGCGGGACTCACAAAAT +GCGGTATTCACATACGACAGAGGAGTATGTAGCCTTGGAAAACCCTGACCCCTGCTACAG +CAGGGAGGAACCTTGAGGACTTTATGTTAAGTGAAATAAGCCAGTTACAAATGGATAAAT +ACTGTGTGATTCCACTCATATGAGGTACCCAGACAGAAACAGAAAGCAGAATGGCGGCTG +CCCAGGGCTGGAGGAGGGGAAAATGAAGAGTTTGTATTTCACAGGTAAAAAGCTTCTGTT +TGGGAAGATGAAAAGCACCCTGCAGACAGACAGTGGTAATGGCTGCAAAACAACGTGAAT +GTTCTTAATGCCACTGACGTGCACAATGAAAAATGGTTAAGACGGCAAATTTCATCTGAT +GTGTATTTACCAAAATAAAAAGCAAAACCCCATGCTTGTCATCAGGGGAGAGGAGGTGAG +GGTGGAGGCACAGCGCACCTCCCCAGCTGTAGGACAGGGGGAGGGCGTGGTACTGGCCGT +TTCTCCATTTGCTGATCACCGTGAGAGAGCCTGATGGGGTCAGGCGGCACAGTCTTTTTA +CCACTGAACAGCCACTTCCTGCTGCCATGGCCATGGAGCTGGGCCTTCCACCCCCACCTG +GAGCCTACTGAGGCCCAAGGAGAAGGCACAGGACCCCACGGCAGGCAGGATGTATTTCCG +CTTGTCCAGGCAACTAAGCCACGTCCCCACGAATGGAGGCTCCTACAGAGACAGGCGGGT +CGGGTGGTCCAGTAGGACCAGCAAGCGCTTCCCCAAACCCACTGGCTCCTCCTCCTGGGC +GCGAGGCTCCCTGTGTGGCCAGCTGCCCTGGTGTGGCCATGTGACCGAGTTCTGGGAGAT +GGCGGGTGGGCACTGACCCGTAACCCCCTCTGTGCGGCCCTCCTCTTCCTACCCCCTTCT +GCCTTTGAGGATCAGTGCCCATGTGCCCTGGAAGCCTCCACCAGCCTGGGTCCCTAAGTG +ACCCTTGGAACAGAGTGTCATTCTCACGAATGTCCACACCAGGGGCCCAATCTTCATTCT +AATGAGAAGTCCACATTTTAGAGATGTTGTAGGTGCCTGCCCAGTCTGGCTGAGGCCACT +GAACAGCACGATGGCCCCAGAAGAGCTTCTGGGTCCCCTTCTTTCAACAACGAGGCTGGG +GTGAGGCCCCACAGTGGCTAAAGCGTCGACCCTTCAAATCTCCAGGGCTCCCTTTGTGTC +CTGGAGACCGAGAGGCTGGTGAACAGATGCCAGTACCCAGTGGCTTATAACTTGCTCAGG +CTATTTCATTCTCTTTTCCTTTCAGATCTGAGGGAGAACTCTCCATTAGCAGAGGGGAGG +TGACCACGTAAAAGGACCCAGGCTCCCAAGCTTTGTGGATACAGGGGAGGGAAGAGGACA +GAAGACCTGGAGGGGTGTTTGCAAATACGCACCTGCCAAGGGTAGGTATCTTACCCGGCC +AGACAGGGGCCCTCTTCCTCTGCCTGTTGCTCCCAGCTGAGGGAGGAGAGGACTGACTGG +GCCTGGATCCCACAAGGTGGTTGGAGGTCCCGTTAGGAGCCAGGGCCAGGGAGGCAGCCC +CCTAAAGGCCAGCGTGGATGCCCGCCCACCCACCCCTGCCAAGGGCTGCTTGGGAGTATT +GCAGGCCAGACCAGAGTCTCAGCCACAGGTGGAGACAGCTTTACAGATGAGACGAACCAC +TTCTCTTGTGGATTTTCCACGGTGACGAGTCAGCTGTATCACTATCATATCCCACAGATG +CAGTCTGCACACCCCCCAAGCTCAGGGCATAAAAAGGTGTCTTCATGGAGCAGTGCCCAC +CTCTCCACAGCCTGTAAAGCTGCACCAACAACTCAATGACATTCCAGCAACTTCGAAGAG +AAAGTCCCGTCTCCCCAGGTCTGCCTTCCTGCCTTCCCCAATTCAGATCCCACAGCTCAC +GGAATGGCTCTGTGTCAAACTCTGAAGGTTGGCTCACCCAGGGCAGACAGACAGAGGGGC +CTGCCCAGGAGCCCGACTCCAGCTTGCCAACTCTCCTGTCACCTAGAATCAAAGCCACCG +AGCGGAGAAGCCCCCGGTCCAGCTGCCTGCGTCACTTTACCTTCTTTGAAGACAGCAGCA +GGGTCTGGACTGGCTCAAAGTCCTGGAAGAGCTGGGTCTCCTCGATGATGTGAACAGCGT +GCTCGAGGCTGATGGCTTTGTGCAGAGCTCCCCGGTCTGCAGGGCCAAAGCTACAGGTCA +GTGACACTAACCCAGACACAGAAACCAAGGACAGTGACCACAGCGGCAAACTTCACACTC +TTCACTCTCAAGTCATTCCCTCCACAGATACTTAGAAAACAATGATGATTTCGCATTAGA +AACAAAAAAAGGAAAAGGCTTTGGCAAAACAGACAACTGGAAACCCAAGTGTTATGGGTT +ATTCCAGTTTTTTTCCAAGGAAAATAAACTGTTCCATGGTTGACCCCAAGAATCCTCACC +AACAGTCGACATTACACTTGAGGCTAAGTGCCACATGAGGGGGCTCCCATGCTCCACCAG +CCCTCGGGGTGTCACTGGTAAGTGCCCTAGGCAGGCGGTGAGGACAGGGGGCATGTGAGG +TTGGCTGGGAGGCTCCAAGGGCAGGCCACAATGCGCTGCCAGCCACCGTGGCTCCTGGCC +CCTGTCCCTGTTCCAGAAGTGCTTATTTCAGAGTCCACATGCCAGGGCACATCTAAAACC +TGGCTCCTCGGCCAGGAAGCAGGGACGTGGTCCTCTGCCAGCAGTCAGGAAACGCCAGGC +TGACGCCTCCTCCCAGGTGGCTCACACCTGCCCCCTGCGTGGGCACTGCCCCAACTCCTC +GGCGGCCAGTACTCCTCTGCCCCAGCCCAGCCCAGCCACAGGCCAGGACTTGCATTTTTA +TTTTTAACAAGTACCTCCAGTAGCCTGGTGGTCCCAGATCTGAAAGCCACCTGGTGTGGT +GACTTCTCAGAAATCTTCTTACGCTCCCACAAACCTCCCAGGTCACCTCGAGGGAGGCAA +TGGAACTACTCACGAAAGAATAATTGGATTTCCCAGTTTTCCTACCAGAGGACACAGATG +TGCTGTCACTGTCAAGCCTGCCAAGCCCTCGGAACCCACCTGTGCTGACAAACATGACAT +CATAGACAGTCCCATCCAGGGCCTGGGTCCGGTCCACCACGATCTGGGTGTAGTTCACAT +CTTTCTTGATTAACCTGGGCCTGTTGTCTATTGGGGTTACCGAGTCATCCATCAAAGGGT +GGTCTTTAACGAACTGCAGCGTCTTGTCTGGCAAATTCAAGGAGCTGGTGTAGTTGGCGG +CCCGTGCCTCGCTGTCGATGCACTGCAGGGAGAAAATCCCCGCTGTTAACGTGCTCGTGT +CCCACCACGCAACGGGTGCTTCCACACAAGCAGCCAACGCAGGGGGGGCTGCAAAACCTG +GAAACCACACAATGCATGCCTTGAAATGAGGGTAGCAGTGAATAACTTTACTATGAGGAA +AGGTGGCCTCTCCCCAGCCAGCAGAGGACACAGTTATAAAACACATCTGCAAGACAGAAT +TGCATTCACGATACATACTCAGGGAAGGAATTTTTATCTATTTGTAAGTGAAAAACACTT +ATTGAGCTTTTGAAATTAAAAAACAGAACACTGATTTGCAGCTTTCTCATGAAAAGAATG +CTAAACATGGCTAAAACCAGGACAATTTAAAATAGCATAAGAGCCTGAGGGATTCTTTTT +TCCTGTTCTAGCTCCCTGATGTGTGTAAACCAAAATCTGTGACCATGAGTGAACACATTT +TACGAAGCTATGCATAGAAGGAGCCATGATGGTGTCAGGGACAGCTGCCCTTGGGAGGGA +GCTGGTGCTGCAGTGAACTCTGAGGGCCAGGACACCCCATGTAGGTCACAGCCCCACAGA +GGGCTGTGCACATGCCTGTCACACCCATTTCCCCATGTGAGGGAAGGAATCGGCCTGGAA +ATTCCCAATTTCTACATAAAGTTCACTATATTTAGGAGGAAAAAATGTGACTCCTGTTGA +CTAGTGGACAGTGCAGAGGCCTTTGCCAAGGAATCATGTGTTTCTCTGTAAGAAACTGAA +AATGAAACAGACCTAATTGTTATGCAATGTTAATTGTGCAAAACAGCTGCCCCAGCCTTC +TTGTTTGTGCAATAGTGTAGCAATGGCTGTTACGTAACATGCAAAAGGGAAGAAGGATGA +GCTGTGCTCATCGGCCGTCCCTGTCCCAATGCAGAGAGCCTTGGCGTGGCCAGGTACCCA +GCCCATGAGCAGGCCCCAGTGCCTGTACTGGATTCCATGCCCTGGGCCTTGAAGGGAAAG +CACGGCCCGCCCCCAGTGCCCCAGCTCACCGCTCCAGGCCGCGGCTTGGGTACCGGGCCA +TTATAGCGCACCCACTTGGTGTGGGACTGCTCCACTGTGGTGCTCTGCATGTACTTCCCG +TGGGAGAAGACCTCCTCGGCTGTGGACAGGTTGTAGGCGCACACTGCCGACAGCCCCACG +TTGTTCCTGGGGAGGGGAAAGAGGTGACGGGACCACCTGGCGGCATCAAGGGAGCAAGGA +GGGGGACTCCACCCAGGGCACTTACAGCTGTGGGGTGAAGAGTGCATAGAACACAGGCAC +CTTCAGGCCCGGGGACCTGAGCACGAAGACATCCCGCAGCACATTGAAGACCAAGCCGCT +GTCTGGCCGGGAGCAGATGAGTCGGGCTTTCAGGAAGGAGGTCCATTTCTTCTGCAAGGT +CCTCAGGCCGCCCTGGTCCCCCTAAAACCCCAACAAGAAGACGTGGTGGGCCGAGAGTGG +ATCCCCTGTGAGCAAGCACTAAGGTCAGAGGTGCACCCCTCCATGGCCCAGCACAGCGCG +GCTGTGCCTGACTGAAACAAAGCTCGGGCAACAGGAGACAGATGCCGCAATTATGTGAGT +GGCCCGCAGCACCACGTCCAGGTTCCAGCTTGGATCCCAGAACGCTCCTGGGTTAACACA +CAAAACAAAACGGACAAAAGCCCTCTCACTGAAAGCTCATTTGATCGTCCATGCCTGCCT +GTGCCCAGCATTCAGTCCTGCAACCGCAGAGGTGCTGCCGTGCTCACACACTTCCAACTG +CCAAGGCCCCTGGCATTGTGTGACTTTCCTGACATAGGGCCCATCAATGAACATGCTCTG +GGTGGGGCAAGTGGCGGCAGCCTCCTTCCAGGGGACAGCCACCGGCCCTGCAGCCTGTCT +TGGGCAAATGTGTGAACCTTCCTCCCTTTAAAGGAATAGATCCTTCACTTCCTTTCTACC +CAAAGTATCTGCTAAAGTGCTTTGAACCTAAGTTCTTTATAAACGCTTTTCAGGGATCCG +ATGACCAAGACACAATTATAAACTACACATGACTGTGTGTGGTCTGGAGAGAAATACTGA +AACCACAAAACCTGAGTGCAGAAGAATATGAAATAGAAGCAGCCTTACTTATTTTGGACA +CAGGGAAAATGTTCCCCCTTCATCTCTGCTGTGTGATTACAGGAGCCCAAATTCTCTTTT +TGATAAAAGGACTTCATTTTCCTCCTTGATGTTTTAGCAAAGAATAATTTCTAGCACATT +TTTCGTCAGGGGTCTCATGTGGCTTTCAGGTCACGGGCAGCAGGTGAAGGGTTCATGTGT +GCCTGCGTGGTAGGCAGGAGCTGTGGGGCCTAAGCTCAAACCACCCTAGTCCAGGAGTTC +AAACAAGTATGGGGAAAAAAAAGGGATCAGAGGGGATGACAGCAGTGTGCCTAAGACTTG +TAGAAACTTGTCGGGGGTGGAGGTGGCTGCTCTGTGCATCGCTGAATCTGCTCACTGATC +CTGCTGCAAACCCTCAGTGCTGGGTAATAAGTCAAGGTCAAGGCAAGTCTGATCCTTGGC +TTCCCGATGGCAGGGGAGGGCTCGAGTCCCCTGGCCAGTGCTGCTCTGACAGCATTCTGA +GCACTGTGCACGCCTGCCAGGAGCTCTGGCCCTGCAGCACCCTCCCCATCTCAAGGGGCA +CTGGCTTGCCCCCAACACTGATACTGTTGATAGGATGGTTTCCTGGTCTGCAAGACAGGA +GCATGGCAGCCACGGCTGCGGGGCTGCGGGGCAGCTGGAGGATCTGGTCAGTGAGCCCTG +GCTACGGAAGGCCTGGGCAGGGAGCAAAGCACCAGGTGGATACTCAGGTGTGCACATCAC +CCAACCTTCTTCCTTATGCAAGGGGCTGTTAAGGGAACGGTGTCAAAGGCACCCACTTTT +GTGCGCCATAGGCATGAAAGGAACCCTGCTTCTCTGATGTCCTGATGGTCATGACTACAT +GAGAAAGGGCCACGCAAGAACTATCTACCAATTTCCATGAGAGACGAATGGCTACCTGCT +CCGAGATGAGCTCCTGGCCAGGGACATGGCGGCTGTGTTTCATGTGGTTTCCCCCAGCTC +CCCTGAGGCCTGACAATCCACCTCCTGGAAACTGCCACTGAGCAACCTTGAGATTTCCTG +TAATCAAGCCCATAGGCCATTCTCTTGTGCTGAGCACTGTGCCTACAGTGTGTCATTTTA +AAGGCACCCTCCCCTTTTAATGTACTTAAAGATTTGTGTTTTGACAAACTTCTGTATTGG +TTCTCTCTTCTTAATCTTAAGCTGTCGGTTAATGTTTCACTCTTAGGTAGATTAAGAGCC +AAATGGTGAAATTCCAACAGACTCTGGTGAATACATTCCACAAAGCCTTGCTTTTTATAA +GCTAGAGGTTTGAAGAGGGTGCATTAAAAGAAAGAACCTCCTGAGAAGAGGAGGCTAATG +GGTCACACATGGGGGCCAGCACTCCCTCAGTCCCCACAACCCCCAGAAATAAGATCCATT +GAGAGCTGCATCTGAGGCCCAAGGGAATAAAGTGCTAGGGAAAGTGACATTTGAGACGAA +GGTCAGGAGCCACCCATCATCCAGGCACACTATTGCCATGGCAGGGGCCAAGCGAAGCCA +GAGTGCCTGGCACTCACCTTGCACACTCTTGCTATCCGTGGGATCAGCACCCTGAACACA +AACTCATACTCCACAGACACCTCCGTGAAGAAGAAGTAGACCCTGTCATCCTCGCCGTCG +GGGCTGTCTGGGCTTTTTCGGATCACGTCAGCAAACACGAAACTAGGCTCTGCAGAGAGA +GGACAGTGATTATCCCAGAACACAGAGCTGGGGGACTGCCTGCACCCATGAGGTCACGAG +GCCGGCCAACACTACCTTGGGGGCCTGAGGGCTTCCCTGCAAGGATGTCTGGAGTGTGCA +CATGCCACAATCCAAACAGAAACTCCAGGATCTGAGGATGATGACAGCCCTGAGCCCAGA +TGGTGCCCTACCCCCACCTCCTCGGCCTCAGAGAGGTGCCCCCGACAGTGGTTCTGCAGT +GCATCCCACCCAGGTTCACCCCAAGAACTGAGGCTGGGCCTCCTGACTGGAAGGCAGGGA +GCCAGATGGTACCAGCATCAGAGACCTACGTAAGGCATGCATTTGCTGGTTTAAACAACA +CATGCTTCACATAAACAAACTCTAACCACCAGATCCTGCCCCACCCTGAGGAATGGCCGA +CTGTCCCTGAATCTGGGGTCTTGGGATCTGCCCTAAGGTCAAGAGGTTCAAAACCCAAGG +CTCTACTGGCTGGCACCCACAAGAAAAGCCCCCATGAACAGCCACCAGCTTCTTCCTGCA +CATTGAAGACGGACATCGGACATGTGCTGCTGGCAGCAACAAGGCACCCAGAGCCCATCT +GACCGGGCACTAGAGGCTGGGCCCGGAGGCAGGTCCCACACCAGTGTTGGTGCCACACTT +TAATATCATTCTGGAAATTATACCATGTCCCCATCTGATTAGTCTTAGTTTACCATCTAC +TATCAGATTCTCAATTTTATGAGAGTCTCCCAAATCCATTTTTGGGGGGTTAGTGGGGAG +CTGTCTTAAAACAGTACTCTGTTACCAGTGAAAACACCCAACAAGGTGCCCTGGGACTCT +GGCCATTGCTGGACAGTTTGGGAAGTATCCCCCACAAACAGGGGCTAACACAAGCTCGGG +GGCCCCCAGGGCTCAGAGACAGAAAAGGAGAGATCAACAGGTGTGCACTCATGAGGAGAC +ACGCACCTCCCACTAAGGTGCACTGCTCTTCCTTACCGTTCAGCCAAGGGATTGCATATT +CTGTCCTCAGAGGACTGTGGGAAGAATTTCGGGAGATGATGGGTTCACTTCCCAAAAAAT +TATACGACGTCCCCGAATAAAGTTCTCCATCTGCAGGGGCCCAGAAGAAAAGAGGAAAAG +GGAACCAACCTCTCAGGCTATGGCACCAACACTGGGACAAACATTCAACACGGTGTTTTC +CTTTATAACCCAATTAAGTCCCTGCCTGGGGAAAGGGAAAGACAGTCTCCTCAACTTTTG +GGGTGTCCTGTGTCTTCTAGTTCTTTCTTTTTCGAGATGAGGTTTTTTTGTTTTGTTTTG +AGACAGAGTCTCACTCTGTCACCCAGGCTGGAGTGCAGTGGTGCGATCTTGGCTCACTGC +CACCTCCACCTCCCAGTTCAAGCAATTCTCCTGCCTCAACCTCCCAAGCAGCTTGGACTA +CAGGTGCGCGCCACCATGTCTGGCTAATTTTTACATTTTTTGGTAGAGATGGGGTTTAAC +CCTGTTGACCAGCTGGTCTTGAACTCCTGACCTCAAGTGATCGAGGCATGAGCCACTGAG +CCTGGCTTGAGATGAGTTCTTGCTGTTTCCCAGGCTGGTCTCAAACTCCTGTCCTCCCGC +CTGAGCCTCCCGAGTAGCTAGGACCACAGGTGTGCTCTCACTTTGATGGGGATAATTTCA +TGCTCCATGTTCAGCTGCATTTTAAGAGTCATGGGGCAATAAGTAAACATGAGCAAGGAA +TTCCCACATCCAGGAAAATGCTGGCAGATGCAACAGTGGGTACACACCAGGCTATGACCA +CTTGCTCAGAGGTGAGAGACCACTGCAGACAGCATGTGGCTCAGTCAAAACCTTACTCTC +AAACAGGAGCATCTGCTCAGCACGCGGGGATTATCCAAATGACATGAGCCAGCAATGGAT +ACAAAGTGACGTTTACCATGGCGGCTATTATCCTTGCAAACAATGAATTCAAAAGTTAAA +GGGTCTATGCAGTCACATGTGCCTTTTGTAAGGATAGCTCCTATTTAAACAAAGCCAAGG +AAGACAGCACTTCAGAGAAGATCCAAATATCCTGTTTGGTAATTAACATGCCACTGTAAT +CTTCACGGTGAAGGAACTGGAGGGGCAGGACTCACCAACCATGACGGATGTGTAGCTGTG +TGCTGGGTCAAAGGGACATCTTCCTTTGCCATCTTCATTTTTCCCCAGAAACTTAAAGGA +TGTTAAGTTCTACAATTGAATAAAAAGAGAGCACATCATCAGATGGCTGAATTTCTATAG +TAACAATGTGTCTCTGTACCACTTCATTTTACAAATTTGCTCTTCTCGGAAGACCAACAG +GGCCGAGCAGATAGGTGTGGAGCTACAGGAGTCCCGCCCACTAGGGCCAGGGCTTGTGTT +GCTCAGCTCAGGTCTAGACATCAGCACCTTGGTGCCCTTGCTCCGTTGCCCTGGCCAAGC +TTCTCAAGATCTCAGACCCTCAATTTACTCATCTGCAAAATGGAAATGGCAACGCTGATG +GCTCTAGGGCTGGAAAGCCACCAGGATAAACCCAACACAGGACGTGCTCAGTATGTAATC +GGAAGCCCATGAGCAGAATTTTAACATCAATAAAGACGGCATTCTAAGCAGCTAGGTGAC +CCAATAAATAGGAAGCAGAAAAACATAAACAGGCAGAATCTCTACGTCGCTCCACCCACC +AAAACACACTCCAGATGGATCAACCATCTGAATACTAAAAACAGAACCGCACTGTACTAA +AACAGAGCAGGGGCTGGCGTTTCCATCTGGGGGTCCTCTCTTTACCTGGCCAGAGTGCCC +ACAGCCACATGAGGAAAACAATGCACAGATCCAACCACAGAGAGAACTGGAAAGTTCCAC +ATGGGGAAATAATACGGCAAGGTTAAATATGTGACAAACTGGGGGAAATGCCTACAGAAT +GGCAGATGAGGTGTCTCCATCCCTGAACATGTGAGAAGTGTGGACAAACGAGTGAGAAAG +GGCATCCAGGAGAAAAACAGGCAAAATCCAGCAAGTGACAGAAGAAACCCATCTGGACAG +CACAGACGAGAGAGGGGCTGAGCCTGCCGGGAACCAGAGAGCACACAGAACACGCGTGGG +GATGCCACTTTGCAGCCAACAGCCTGGGCATGCTGAAGACAGGCAGGGCCCACGGCGGGG +CAAGGGCACCCAGCACCTCTGCTGCAGGAGGCTGGCTGGAAACACGCTCTCGGAAGCAGA +GCAGGAAGGCTCAGACCACGTGGAAGGCCGCAGCTGACACCCTTGAAAGGCCAGTTAAAG +CAGCACACAGCTCTTCACCTGTTAGGTTAGGGAATGTGAACCCCACTGGATGTGACCATT +TAGCATACCTTGAAAGGAGGTTTCGGGGCTGTTGGGGAAATCTGAACGGGGACTGGAGAC +TGGATGATGCTGGGGAATGATTGAACGTTTTCTTAGATATAATGATAAAACTGAAGTTAC +ATAGGAAAATGTTACTATTCTTAGGAGATGCCTGTGAAGGCATTTGGGAGTCACGGGTCA +TAGTTCAGCAAGCACACATATGTACACAGACACACATGTGGACACATAGACATGCACAGG +CACACAGACACGTGCACACACACACTCCCAATTGTGCAATCTAGGTTGCCAGGATATACA +AGTGATACATCTTTTCTGCAGCTGTGAAAACTTTTATTAAAAATATTAGGAAAAATTGAC +GGGGCGTGGTGGCTCATGCCTGTAATACCAGCACTTTGGGAGGCCAAGGCGGGTGGATCA +CCTCAGGTCAGGAGTTCAAGACCAGCCTGACCAACATGGAGAAACCCCATCTCTACTAAA +AATACAAAATTAGCCAGACGTGGTGGCACATGCCTGTAATCCAGCTACTCGGGAGGCTGA +GGCAGGAGAATCGCTTGAACCCAGGAGATGGAGGTTGCAGTGAGCCGAGATCGCATCACT +GTACTCCAGCCTGGGCAACAAGAGTGAAACTCCGTCTCAAAAAAAAAAAAAAATTAGGAA +AAATTATAGGTCTAAATTTAAACCAAATACAGTATCCTCTAACCTCAACAGCTAACCTAT +CTACAGAATGTAAGTTTAAATGACAGAACTTTAAGCTTCTGATTGAGTTTAGCCAGAAAA +ATCCTTTGTTGTGCAAAATGTTTCTGGTCCAACCGTACTTTCTGCACAAAAGTAAATACA +AACGACTGTCTTTGAGGACTGAGGGTCTTACTATCCCCAAAGCACCCCCACCCCCTATCA +GGTTTCGTTGCCAGCATCTGTGGTACAGGCAGCTGGGTAGACCCCTACTATGAATCTCAC +CCCAGACGTCTGTGTGCAAATACCAGGCTTCCTCATCAAGTCTCTAATGAGGCCATACGT +TGTCTTGTCATTTATCTCTGACTCAAGATTGGAAAATATTTTAATTCCAATTAATTTAGG +GTTCTAGCAAATGATGCTTTTCACTGTGGCATATTTTACATTTATCAGGACTCATTAAAA +TCCAGGGATACACAGTAGAAAATGTGCTTCATTTTCCATGTTCACATGGACTTATTTAAA +ATGCTACTTCTCCCTCTCTGATGATCATCACATTGCTCATCAGATTATCTGGATAGAAAG +GACCGTCACACAGGGGGAGGTGCCGGATACCAGGCTGGGCAGTCAAGGATGTGAGCCGGT +GAGGGACAGAGGCCGGACTTGCTTCTCAAGGTGCTCAGCACACTTGACCTGCTGCCCCTG +AGTGGGTGGACCCAGGAGTGGTTCAGTGAGCAAGCTGCACACCACAGCCGACCAGAAGGG +TGGGTCCCACAGCCAGAGCACAGATGCACCAACCAAGAACACACAAGCCAGGAGCAAGTC +CTGACTTTTCCACCTGACCCAGATGCCCAGAGCTGCCAGGCTGTCTGTCCTTTCCAGCAC +GTCCCCTCACCCCATAGCATGTTCAGGCTACCTGTCCTTCCCAGCACATCCCCAATGCCA +TGTTCAGGCTGTCTGTACTTTCCAGCACGCCCCTCCATGGCATGCTCTGCACTAGCACCA +AGGGCTCCCAGCACCTTGAGCTGCACCCCAGGCCTCACCCTTGGCCATGGACACCGAAAC +TTAGAGGAGCCAAGTGGGCTGTGTGCCCCTGACAGCAGCTGTGCAAGACTTTCAGAGGGG +CCACAAGCTGCCCCCGTTTTCTGCAGCTGGCTCTGAGAAAATCCTATTTTTTTTTAGGGT +GGAGACAGCTTTACGTCTGCTTTGAGCCCCCTTCTACTTTAACTGCTGACCAGGCTGGCG +TGAGCACAGGGAGGTGCCCATCAGCCTTACCAGGTGGTCACAGGCCGGCTGGAATGCGTT +GGTCCCACACACGTAAAGGGAAGTGGCGCTGAGTGGCTGCAGCACCCGGATGTAGTTGAG +GCACTCTGTCTGCAGGGAAGAGAAATGCACCATTAGCAACCGTCCAGCCCAGATGCCCTC +CACTATTCAAACTGCTCACGCCGTTCATCTCAGGGGCACAGACCCACATTCACCAACACC +AGCTCACAGGTGGCCCCAGGCCAACGAGGCATGTGTGCATTCTCAGCCTTGTCTTGTCAT +CTAGACCCTCTGCAACTCCTCTTCACACACTGGCCTGTTCTCGTACAGTGGAAGGTTCAC +TGAGACCCCAACCCCACCCCTAGGCAAACCTAAAGCTGAAACTGGCCTGAGTAATTGTGT +CTCTGCAGTGTCCACATGCTGTTCAGGTGCCAAACAGGATTTTGTTTCAGTCCCTAATTG +ATACTCAGCAAAGATGTGGTGACTGAAAAAAAACTCAATGAATGCTTACCTCAAATCTTA +CTGGGACACCCACTGTTGAAAGCAATATATTTTACTCTTGCTAAGTACGTGGACCACTTG +TTCTGTTGCCAGGCCTGGAGAAGTGTCCACCCTACAGAATTTCCTCTCTGTTTCTGGAGA +CCCCACCCTGCCTCCAACTTGCACAGAACTAGGAACAGCGACACTAGGTCTACCCAACCC +AGGGTCCCAGTCCAGCCCCCATGGGAGTGGCTGCACTAGGAGAGCCTGGAGCCCGGCTTG +GCATCAGAAAGGCCCAAGCAGGAAAACAAAGATACCATTTCAGAACCCACTATTTTAGGC +TAAAAGTACTTGCGTTACATGTGCTATAGTCTGAAATTATCCCAGATTAGGAGAGTTCTC +TTTTTTAGACTGGTTGGAAGTAATTCACTATTCACCCCAACCCACCTGCACACCCCCGGA +AACCGGAGCTACACTGCACCGCCTGCTTTTCCTCTCATTTCCTAATCTAACTTTGGATTT +AGAGACAAAGACTTCAGTGCAAGTGTTTAGCATTTTGCTAAGAAAGTTTAGCATAGACTT +CTTTGGGTTTTCTTTCTTCTTTTGCCTTTAACTCAGCTTGTCTTGACCACCATTGAGGAA +GAATGCCCAGTGCCAGGTAGGGACATGATGGCTCAGAGGGTGATGAGGGTAACCTAGAGC +TGCAGACGGGAATGAGTATTCGGCCCAGGGCTCCCTGAATGAGTACCACACTGAGGGGCC +TGAGGGACCAAAGGGACGGACGTGTGCCAAGAATCCAAAAGTCCCAGTGATAGAGAAAGG +AGCCAGAGAAAGTCTAGGCAGACAGGGGCAGGTCCCTGGCAAAACCCCACATGTGAGCCA +AAAAGCCTAAAACCCGCAGCCCAGAGTGAGAACTTCTATCCCTGTTTGCCCGCCGTCTCC +CGATTGGTTCTTTCTGAACATCTTTTTACAATCAGATGTTGCCTTTTCCGAAACTACCCA +CAGCCCACCCTGCCCTCATCCTGTGCCTATAAGAGCCCAGACTCAGTTGATAGAGAAGAG +AAGGTGCTGGACTAGAGAGAGGTGACTTGACTTCAGAGGGATGGCTGGATTTTGGAGAAA +TGGCTTAACTTTGGAGAAGAGCCGGCCAGAGCTGGCCAGACTTCAGGGAAGATTATTTGC +TCGTCCTGTTCCCTCTCAAGCTCCCATCTCCGCTGAGAGCCACTTCCAACACTAAACAAA +ATTCTCTGACTCCACCATCCTTTAAGTGTCCATGCAACCTCATTCTTCTTGGATGCCGGA +CAAGAGCTCAGGACCCTGAGTGTGTGTACCCAAAAAAGGCTGTCATACTGGCCCTTTGCC +CTCACTGGCAGAGGACAGCTGTCCCACACAATGAGAAAAGGGGCCCACTGAGCTTATAAC +ACACCACTGTCCATGGAGAACAGAGATAAGAGAGCACTGTAACGCACCCTCTGGGGCTGC +GGGGGTCACAGGCACCCCAACCTGGGTGCCACCCTCAGGGCTCACACAAAGCCTGCTCCT +GCTGGCACCCAAAACAGCTGGCCAGATCCCACACTTGCTCACTCATGTGCTCCCTCCTGC +AAGAGGTTGAGCACAGCAGGCCGAATAAATGGGGCATCTCTGTCGCAAGTCCAACGAAGG +GGTTGAGAAAAACTGCATGACTAGCAACTCCTCCAAGCCTAAGGCCTCTGGGTGCAAGGA +GGCAGAACAAACCCTGAATTTCTGCACTATTCACCAGTGGGCTTCACTATTCACCAGTGT +TCTGTAGTCAAAGTTTCAGGCCATCTGAATACATTCAATTCATATAAACTTTAAAAAAGT +ATTTCTCAAAGGCCAAATATGTTTGGCACCTGCTTTGAGAAACCCAATCCTGATACTCAG +GAATAGAGGGATGAGCTCCAAGACGCATCACAACAAAACCAAGCCCAGCAGAATGAACAG +AGCCTGGAGAAAAGGCTGGCCTGCACTGCAGGCATGCTGGCATTCAGTAGATTAAAACAA +CCAAGAAATACTTGAATGGGATTCTTTGTAGCTTGCAAAAGAAATTTACCTGTTTTGATT +TCCCCTTTTCTGCACATTTTGCTTTTTTGTCTTCTGAGACCTTCCAATACACCTGTTGGG +ATAGAGTCCATATCAGTGCATATTCTTTTAAAGAGATACTAGTATAAAAATGCACAATTT +TAAAAGCACATGATAGAGTTTAGAGCCTAGAGGTTTCTCCTGAGATGATCAATTCTCAGA +CTGCAAGGGAGGTTCAGAGAGCAGGGGAGCAGCCTGGGGCCTTCATGAACATCCTCACTG +TGATCCTTATCCTGAAACCAGTGGAGTCTGGAAGACCAGCTCCAAAAGTTCCATCACTCA +CCATAAAACAGCAGCAAAAATCAAACTCGTGAAAGTGGAGAAAATTAAATTATTTTTCAA +AAACCTAAACCATAAGTATTTTCAAACATCAAAGTGGGCTTTTTTCCATCCATTCAAAGT +GACTCTACAGGCCGGGCGCAGTGGCTCACACCTGTGATCCCAGCACTTTGGGAGGCTGAG +GCAGGCGGATCACCTGAGGTCAGGAGTTCCAGACCAGCCTGGCCAACATGGTGAAACTCC +ATCTTTACTAAAAATACAAAAATTATCTGGGAGTGGTGGCGGGCGCCTGTAATCCCAGCT +ACTCGAGAGGCTGAGGCAGGAGAATCTCTTGAACCCGGGAGGCGAAGGTTGCAGTAAGCC +GAGATCGCACCACTGCACTCCAGCCTCGTGTGCCTGGGCAACAGAGTAAGACTCCGTCTC +AAAAAAAAAAAAAAAAAAAAAAAAAAGTGACTCTACAGTCCAGTTTAAAAAAAAAAGCCA +CAATATTCACTGTATCAGTAGAAAGGGAGATTTACGATTCCTTAAACTTGCATGTTGGCA +GCAGGAGGAAGTGATGAACTAACACCACCAGCTCAGCTCAGGCACCATCTTAGTAAGATC +CATGTTCCTACCACCTCTTCTTTCAAACCAGGGACAATTCGTGATCAGAAACTTCCAGGG +GGTGGGGGCCTTAGCCCCTTGCCCTCCAAAGCCCCCACAGAATAGAAAGCAACATAAGAC +AAAAGGGAAGGTTTCTATATCTATCTCTGCCTCACCTTCCCCAAAATGCCCCCTCTCTCT +GTGATGTTCCATAACTGATGCAAAAGAAACCAGTAACAATGTATTTTTCTCCACCAAAAG +GCTTGTAGCAGGTGTCAGGACTCAGAGGTTAGGAAGCACACAGGGCTTCTAGGAGGGAGA +GTATGAGGAGAGGAACCCCACTTTAGGTTTCTAACTAACTCTGTGAGTTCCTGAACAGCA +CCCAGGCTGCAGACACAGTACTAAGGGAGTGTCATTTCATAGAAATGGAAGTCCTGATAG +GGGCACACAAAAGCGGAACAGAGTCTCATTTAAAATAGCCACTTCCTTCAGCATTTAAAG +TACAGATGATTTCGTCAACTCGCATGAAATGCATAAGGACAAGGGAACGTACACTTCAAC +AGACTCTTGATCACGTTTGCAGGGATTTTCACTGATGCTTGGCGGGGGTCTCTTTATTTT +TTTCTTTTAAGTATAAGAGGTCCCCAAGCCTCTCCCCAACCCCGAGGGACCACCATGGTG +TCATTAACAGAGCAATGTCTGGCTCTCACTGAACACCTGTGGGGCCAGCACAAACACACT +GTCCACAATTCCCCCAAGACCGAGTGTGAGCCTGTGTGGTCAGGAAGGCGCTCAGAGGAA +GAGAATTTAACAGACACGCGAAGAGTAAGAGCTGAGTGAGGTGAGACCACCACATCTTTC +TGCTCAGAGTGCCTCACAGTGCTGAATACTTTGTTTTTGTTTTTTTGAGACAGGGTCTCG +CTCTGTTGCCCAGGCTGGACTGCAGTGGCATGATCTCAGCTCACTGCAGCCTCGACCTCC +TGGGCTCAAGTGATCCTCCCACTTCAGACTTCCAAGCACCTCAGACTCCCAAGACCTGAG +CCACCACACCTGGCTATTTTTTGCAGTTTTTGTAGAGAAAGGGTTTCGCCATGTTGCCCA +GGCTGGTCTCAAACTCTTGAGCTCAAGTAATCCGCCTACCTCGACCTCCCACAGTGTTAG +GATAACATGCGTGAGCCACAGCACCCAGCCAAATACTTGTTTTCAGAGCATAATGCTCAG +AGCTCATTTATGTGTCAAACAGAAATTGAGAAATAAGCTAGACCCTGGAGATGAAAACAA +AAAGAGATCTGGGCAGAAAATGTCCAGCGTGAACCTGGAACAGATTCCAGAGAGCAAGAA +AACTAACCCCACACCGCGAGGTCTCAGGAGCCAACCCAAACAGGCTGCTGTTGACCATGG +ATGCGACGATTTGAGCATGAGGTAGGTGTTTCACTGTGATGGGTCAAAGAAGAGCAAATA +TCTTTAAATCTATGACTTCATTGTGACACTAAAAATCAATCAAAAAACTCACTCTTGCCC +TTCAGAGGGGAAACTGACTCATTAACTCATTATTCTGAAAACTGGTAAATAAAGGCAAAG +ATTCCAAGCATCGATTCTGCATTTCCCAAAGGAAATGGGACCTCTACGGACCAAAATAGC +TGGTGATGGGCACTTCCCCTTTTATACGATTTCCAGCTAACAAGTAGAGAAGGAGAGGTA +GAATCAGAACATTGCGTTTTGCAATCTTTGATGAGAAGAGCATCTAGACTTCGCTGGTCA +AAGGCCACCGAGACTGAGGAGGAGGAACACCTGCCTCCATGGAGAAGCCCGCCTCACAGC +CCTGAGAGGGATGAGCCTGGATCTGACACCCAGCTGGGGATGTGAAGACAGAGGTGCATG +CTAAAGACACCATGAGTGGGGCTGGGTGTGGTGGCACATACTTACAGTCCCAGCTACTCA +GGAGGCTGAGGCAAGAGGATCACTTGAGCCCAGGAGTTTGAGGCTGCAGTGAGCTACAAT +CAAATTTTAAATTCGGTTTGATTTTTTAAAATGTTTAAAGACACCGAGGAATCAGGAGCA +ATGTGAAGAGTGGGACATGGGATGGGCTGTGCAGAGTAGCTTTCTCAGGAAGGAAACCGA +GGCTGGCTCCTAGAAGCGGAGACTGAATGGACAGGGTGACCAGCTGCAATGGATTGGGAC +AGCGTGGTTGCAACCTGATTCAAACTAAACGTTTGAACCAACTAAACAAGCATCATCCAC +AAGAGTCGGTGAAATATGAACACTGGCTGAATGTATGATGATATAAATTTTGGAGAAGCT +ATTTTTGATTATTTGCACGACAAGGGGCCCTTTCCAGTAAGAGATACCCAGATGAAGAAT +GTGGTGTCGGGATCTGCCTCAATGCCCCAGGAGGTGGAGGGTACTGTAGGCAAGACTGAA +CACCCGGCCTTGCATAAGCTGCAGTGGGCACAGGGCTCATGGCATAGCTGTCTCTGCTCA +TAGGTATGTTTGAGATTTTTTCATAATAAAAAGTTCAAAAAAAAAAAAAGCAAAGAGGGT +GGTCCCCGGGTGAACTGCTGGTGGACACCCAAAGATGGGGCTGCATGGTCACAGCTACAG +AATGGAGGCTCCAGGTAAGTCAGCCCCCAGCCCCACAGTGGGGCCAGGAGAGGCTGCCCA +CTCAAGCTGGGCTATGTGGACATGCAGGGGAGCCCAGGACGTACCTCATGCTGCTTCTCG +GAGATGTTGAGTGCGTTCACAGCGAAGACCGCCTCCCGGGCACCTATGTACAAGGTGTCC +TTGTCCTCGCTCAGCAGCAAGGCTGAGTAGTTGTAGATGTCTGGCTCATGAAACTGCACC +AGGTGCACCTCTGTGGGATGCAAGGGCAGGGTCAGAGTGGGAGGAAGAAAAGAGCGATGG +AAGCATTTTTAAACCTGAGCACATCCTAGGTCCCTGTCTCAGTGACAATGAGCACGTCTG +GGTGCAGTCATGTCTCGAGGGCCATGTGTTGCTGCAACAGGCACTGCTACAGTGGAGGTG +GCCTCAGTCAACGCCAGACCCACAGTGTAGCCATCAGGTGTGCTCATGGGAACCACTCAC +AGCCCTAGAGCTCAAGCCCGGAGCCAGTGTGCTCACTTTGAAGCTGTGAGTCGGACATCC +CTTCCTGCTCCCTCAGATCCCAGAATCCCAAACCCTGCTCTGCCAGATGCTTCCTGTGAT +GGCTCCCACCCTCTGCCCACCCAACTCTGGTCTACATGCCTTGTCATCCACAGATTAGGT +GTACAGGAATACAATGACTTAGGATTTTCTTATTCAGGAAAAGAATGTTTTACTTCAAAA +TCTTCACAAAATTTCTTTTGGAGAATATATCCATCAACGAATGCAATTCTCAGTGATCAC +CACCACAAACTTATAGACAGAGAAACAAGTGACGTCTCTTTGCTTATTAGGTTACTGTAT +CAATAGCTACTTAGGAAAATGAAGATTTGAGCAATAGCTGCTTAAGAATAATATAAATGT +ATCAGCATTATTTTTTTTAGGACCTGTTTCTTCAACTGTCCTGACAACAATTTGAGCATT +TTGACCTTGGCTTTTTACATATTACCAAGAGTCTGCTTTATTTAAGAGTCAGGTGGGCCA +GGTGTGGTGGCGGGCGCCTGTAACCCCAGCACTTTGGGAGGCCAAGGTGGGACGACTGCT +TGTGTCCAGGAGATTGAGGCTGCAGTAAGCTATGATTGTCCCACTGCACTCTAGCCTGGG +CAACAGAGCCAGACCCTGACTTCGAGAAAAAACAAAGAGAGTCAGGTGTTCATACTTTCT +GTTCTAATTTTCCCATGTGGAAGAGAGATGCACACAGGCAGCAGGTCCTCTCTCTCAGCA +CAACAATGGCCTATATTGCTGACAGCTCTCAGCCACCTGCAAGCAACACCTTGCTCAGGA +CCCAGGGTGTAAGCTCTCAATCCACTGAGTCAGAAACCCGGGTCCCCAGACACATCCTCC +AAGAGAAGAAATAACTAAAAAAAAACTAAACAGCAGGAAAGGAAAGTAGCTGGCATGAGG +CTCAGCTGCACGTAGGACGAGCATTCTTATGATGCCTCACTGTTCTTCTCAGGCGCCTGG +AGCAGACGCTCAGTGGGGCGGGTGCTTTGGCAGCACGCCGCGAACATTACTAGGTACGAG +GGAGGGAAGCTTCCTGTCAGGGGTCCCCAGATTCAGAAACCAAATCAGGAGGTCTGCACG +AGCCTTGCTGAGTATCTACAGTTGTCACAGCCTCTCCCTTAGATCAGCTGAGTAGGCCTG +TCTGCTCAGACAAAAGTTCTCAGAGCAGAGAATCCAACAGATCACATGCCAGCATCCTCA +GCCACCTGCCTGAGCATCCCAGGAAGTGGAGTTCCTGTCCCGTCCCCAGCCACCCGCCTC +AGCATCCCAGGAAGTGGAGTCCCCATCCCGTCCCCAGCCACCCGCCTCAGCATCCCAGGA +AGTGGAGTCCCCATCCCGACCTCAGCCACTCACCTCAGCATCCCAGGAAGTGGGGTCCCC +ATCCCGTCCCCAGCCACCCACCGCAGCATCCCAGGAAGTGGGGTCCCTGTCCCATTCTCA +GCCACCCACCTCAGCATCCCAGGAAGTGGGGTCCCTGTCCCGTTCTCAGCCACTCACCTC +AGCATCCCAGGAAGTGGGGTCCCCATCCCATCCTCAGCCACCCGCCTCAGCATCCCAGGA +AGTGGAGTCCCCATCCCATCCCCAGTCACCCGCCTCAGCATCCCAGGAATTGGGGTCCCC +ATCCCATCGCCAGCCACCCACCTCAGCATCCCAGGAAGTGGGGTCCCCGTCCCGTCCTCA +GCCACTCACCTCAGCATCCCAGGAAGTGGGGTCCCCATCCCATCCTCAGCCACCCGCCTC +AGCATCCCAGGAAGTGGAGTCCCCATCCTGTCCCCAGCCACCCGCCTCAGCATTCCAGGA +AGTGGGGTCCCCATCCCATCCCCAGCCACCCGCCTCAGCATCCCAGGAAGTGGGGTCCCC +ATCCCGTCCTCAGCCACTCACCTCAGCATCTCAGGAAGTGGAGTCCCTGTCCCGTTCCCA +GCCACCCGCCTCAGCATTCCAGGAAGTGGGGTCCCTGTCCCGTCCCCAGCCACCCACCTC +AGCATCCCAGGCAGTGAGGTCCCCATCCCAGGCCATCAGCACCCCTGCAGGTTTCGTCAC +TCACCTCTGTGCTCCCAGGTGATCCGGGGTATGGGTGCAAATGCCATCGCTGTCCCAAAC +ATCACTGCAAGGGCCATGAGCAGCCCCCTAATGGGGGTGCACATCCTCATCAGGTAGAGG +CGACCCCAGGGGCTTCAGCAGCAAAGGCTCACGGCAGCAGGTGGCCGGGCAGGTGTGCTA +TTGCAGATGCGGCTCAGCGCCCCAGGACCAGGGCCAGCAGCACAGCCTGGAGCTCGTGAA +CAGCGCGGTCCCTGAGAATCCACATTTCCCAGTTCTCCAGGTGAGGAGGGGTCGCTCTCA +CCACCGCAATGTCAAAGCCCACTTGATACTTCTTCAGGGCCTCAGAAGAAATGCTGGAAG +GACATGAGAAAGAAAAGGCAGGACCCATGGTGAGTGATGACCTGCTTCTCACTGCTCTGT +AGCCCCTCTGCTTGCCCTGGATCCTCACCCGGGTCCATCTGCTGAGGAATACGGAAGGCA +GCGGGGGACAAAGAGAGTCTTAGAAGTGGACAGCCCAACGGACACAGGAAAGCGAAGCCA +GGGTCTTCAGGAGTCAGTGCTTCCCGCTCCTCCAGCTACCAGCCCAGAACACAGGACAGA +CACATGGAGAGGACCTGGTGTGGGGCACCCGGCAGACACACATGGCCGGCTGGCTGCCCA +GCTTCCTTCCTGTGTGGCTGCTGTGTCCAGCTGGTAATGAGATGAAAATGAAGGAAGAGA +ACTCGGGTTTCAGTTTCCCTTAGAGACTCTGCCTTTGTAACGCTCAGCGAGGAAACGGCC +AGAAAAACCAGAGGCTGCAGAGAGAGCTAAGATGTACATGTGAGTGCACACACATGCACA +CACACAACATATGCGCACACATATGTACACACACACATGCACGGATGTACACCTGTAGAA +ACACACGCACGTGAGGCCTCACCACGCAGGAGTGTCTGACCTCCTGCCCCAAATGGGACC +CTGCTAGCTCTTCCAGTCTCACTTAAAGAAGTCTGTGCACCATAGAAATGGTGGTAACTC +ACTCTGATTTGCCCAGTAAGAAACAGCCCTTAGTAAAAGAACAGGCTTAATGCTGCTTAG +TGAAATTGTGGGGCTGGTGGTGGGAGAGGCATGCACAGGCCTCCTGGCCCCATCTCTCAT +GTCCCCAACATTCTCTGATGACTGCATGGCTACTGTCCTGGTGTACCTTTGCTGGGCCCC +ACAGCGTAACCCGCCACAGGACTGGCCCAAGGGCGTCTAGCACCTTGATCTGGGGCCAGC +TGCACCCCTGGGTTCACTCTATGAGAATGTCCTGAGCTGGGCACCCAGTGATTGGGCACT +TTCACATTACACTTCTGTAAACAGTTCACTCAAAACAGCAACCTGGGATCCCTGAGTCCC +TTGCTCCCCCTTCTATCCAGGAGTCCTGTGAGGGTCATGGAACAACCACACCCCTGAGCT +CCAGACTCTAGAACCCCACTCCTCCCTACCACCTCCACATGCCGCCTTCCACACCCAGCC +AGACACAGCCGAAACAGAACCTCACTCTGCTTCCAGCCAATTCCTACAGTCCATGTCCCC +ACCTAAAAAAAAGCACCAGCAGTCAGGGGCCGACCCCATCTACCTCTAACCCCACCCCCA +CCCCCAATCCATAGATGGTGCTGCTGCTCAGCCTCAAACACATCTGGGGCTTGTCTCCTC +CTGTCCATCTCCACCACCATCACTCATCTGAGCAATGCTCACCTCTCATCCTGGCCTCTT +GCTTCCATGGTAGAGATCACTGGCTTCCTGCCCCAGCATCCATGTTCCTGCACCCTCGCT +AACAAAATTCCGAGGTTACTTGGGTTGGCAGTGTGCCCAGCTCACTATATCTCCCAGCTT +CTCTGGTGAGAGTTCTGGCCAAAAAAACTGTATGTGGAATTTATTAGATGGCAATTCCAG +GAAAGCTCTTTAAAGGAGGCTGATTCAGCTAGCAATTCCCTCAGTCCTTCTCTTCCTGCT +GCTGCCTGGAACTAGAATGTGATGGCTGGAGCTCTGGCAGCCATGCTGTCAACATGAAGA +TAAAAGTCTCATTCTAAGAATGGCCAAGTGAAACCCACAAGAGCCTATGAGACCCTAGGC +TATGAGTCTATGCAGACTTGCTAATAAAATTATTAAAATCTTTAAATTACTTGCTTGCAG +ATTTTTGTTACCAACAAATACCATTCCAAACTGACACAACCTCCCTCCAGTCCACTGCCA +CAAAGTAGCAGTGGCCAAAGTCATGCTCTTATCATAAATCCAGATCATATCCTTTCCCCA +TGTGAAATGTTTCAACACCTTCTCATCACTCAGAATAAGGCCCACATTTTCATCATGGCC +AGCAAGGCCATGGACAACCCTACTCTACCTCCATCCAACTGCTCCTCATCCACACTCCCT +CCACTGCACTGTCCTGGCTACACCTGAACACACAGGGCTCGGCCCCTCTGCATGGCTGTG +TAACGGCTGTCTCTCCTGCCTGTCAACACCACTTAGAACATTTCCAGATGTGTCTGTTCT +GAAGTTGCCGGTCTAAATCCCACTGCACAGTCTCATTCATCTGAGAGGCTTTTCCTCTGT +ATAACTGATTGGTAATTAGGAGTGGCTCCCAAAAGCTGCTCCACTTTGAGCTCCCAAACC +AGTAATGGTTTCTACATAGGCTCCCAATGAAGAAGACTCAATAAATTATAGGTTCAGATC +TTCTGAATTCCAGGCACATTTGCAGCTCCTTGCCATAATGGTGTCACTTTTTGTTTGCAA +AACAGAAGTTGACCTACTTGGCCTACAAAGTTGTGAGAATTATCTGCTAAATCATATTAC +TATATAACTAATCAATTAGCATCTGATAATAATAATGTTTATTGCTCTGACAAATACGAA +TGGAGCTCCTGCTAAGCCTGGAACAAACAAGTCCTGGCCCCACAGAACCCACGCCCTGGA +GTGGGGCTGCGTGGAAGCAACCAGCCCAGGGCCTGGCACCCACAAACATCCCATGCCCCT +CCAGGGTCCTGCTGCCCTTGCTCTTCTCAGTCCTCATTGCATGCAATGACAGACATAAGA +AAGGATGGTAACAGTGGTGACAAGCTATCCACAGTCCCTCAAGAGAAAAGCTCCCATTAA +AAACCAGCTACCCCTCCTTTTGGAGCAATGATCCCCTGGCATTTTAAGGATGCGTCCTTT +CTCCCGTTCCATGTGACAAACATCATACAGCCAGTGAGAGCCAGAAGTGACAACGTGGCC +AGGCTGCCCCATCCCTTAAAGCAGAAGAGGACTGCACACTCGCATTGTGAGAGACTTCAC +ACTGGCTCCCGCGCCACTAGAGGAGGAGGAGGAGGCAGGCCTGCGGCAGGCAGGGCCTTG +GAAAGGGTTCTTGTCATGCATGCAGCAAGGACACCAGTGGCCTGGTCCATGTGCTGCAGT +CCCAGCCCAGTGAAACCCAATGAACTGACATTGGCTCCTCCAAGCCACACCCAGACCCAG +GTCCCAGCCAGTGCCAAGCTGTGCACAGCAAGGATAAAGCAGAAACAACCTCTCTCGTGG +CATGTCCCCCAGCTGGGCAAAGGTCCATACACACAAAAGAAACAGCAATGAGCTGCCATG +GGATGGGAGAAGGCGCTCTGAAGACGGATGCGGAGCCTGCAGAGGTAAGGCGTGCCAACC +ACACAGGAAGCCAGCCGTGGAGACAGCCCAGGGGCAGGCGAGTGGGTATACAAACCGCTA +CATCCAGACAGGGGAACGTTACTCAGCATTAAAAATAAATAAGCCATTAGGCCATGAAAA +GACACAGAGGAACTTTAAAAGCTTATCATTAAAGAGAAAGAAGCCAATCTGTAGAAGTAC +ATACTGCATGATCCCAACTATAGGACATTCTGGGAAAGGCAAAACCATGAAGACAGTAAA +AAGATCAGTGGTTCCCAGGGGCTGGGGAGAGAGAGGGTTTTTAGGGCAGGGAAACTAGGC +TGGCAGGGATACTACCACGGTGGACACATGTCAGTATGCATTTGTCCGAGCCTACAGAAT +GTACAACACCAACTGGCAATCCTAATGTCCAGATACAGATGTCGGGTGATAAGGTACCTA +TGTGGGTTCACCGACTGTAGCAAAGGCACCACTCTGTGGGGGGATTCTGAAAATGAGGGG +GCTGTGCATGTGTGGGGAAGGAGCATATGGGAAATCTCTGTACCACCTTCTCAATTTTTC +TATGAACCTAAAGTTGATCTAAAAAATAAAGTCTATTAAAATCAGTAACAACAAGGAACA +GGCCTAGGAGTTCCTTGCCAGTCACAAAAGCAGCCTCTGTGAGGGTTCATGGCCTGGACA +CATTAAGGAAGTAAGTGCCCACACCGGAGGGCTAGGAGCAGAGACGCAAGACCCACAAGG +CCCAGTTCATTTCGGGTCAAATACCAAAGATGCTGGATCACTGTTGGAGAGATATGGTTT +ACATGGGATCTAATTCCTATCTAGATCCCCCAACTGCAATCAGTCCTCTGCGTATCCCAA +TAAGCATGCTGGGGTCAGGCCAGGCTAAGAGTCCAGAGCCAGGAGATGGGAGAACACAGA +GATTTATTTCAACTCTCTCTGGAAACCCAATGAAATGACTCTAAAAGGATATGAACTTTA +AGGATAAAAATGGAGGAGGGAGGTGACTTTGGAATCTATTAATAGGTGAGCAGTAACCAA +CGGTGTGCTGGCAAGCTGTAACAACTGGCTCTCCACGGGGTGGGCAGTGGGGGTGGGCGG +TGGGGTAAGGTGGGGGGTGCCCAGCTTGCAGCACACGCTGATTTCTGTGGTGTAAATGCT +GCTTTCGAGCTCCCAGAATGATGCCGCTGAACTGGGGAGAGGTGCACAGCAGCACCCAGC +ACATGGCACTGCCATCTCAGATACAAGAGGCGAGTAACTGCAACCACACAGATAACAGTA +GAATGCACACGATACTAGAAAGGAATGAGTTCTGAGTATTTTACCTTTTTAAATATAATT +TGTTTCATTTTAAGTCCACATATTTAATTTTTAACAGTGGCTGTGTTTACCACCAACCCT +GTCACACACCACCAGAGCTGACTGATTTGAATTTCAGACCAGAGTTGAGCCAGGGCCTGG +AAGAAGTCACAAAGAAACACAACCTGGAAAATGGAAGCAAGCTTAAAAGTAAAATGTGGT +GAAAGAAATGAAAGGCTGGAAAGTAAACTAAAGAGGTTTCCTAGAAGTTACACACGTAGC +AGAGATGAAAAAAAGGGGAACAGACAACTGGACGATCCATTCAGGAGTCCCACATGAACT +GGCAGGAGCTCCGGGAAAAAAAATGAGGAATTATTAAAGCAGTAATAAAAAGAAAATAAC +TAGAACAGAAGGACCTGAGCTTTCGGAATAACAGCGCCCAGGAGCACAGTGAATGAAAGG +AACCCGCCCACACCAGACACATCATCCTGAAAGGAGGGTTACATGAGGCTTCCAGAAAGA +AACAGGCCACAAAGAAATTACCTCTGAGTGCCCCACTGGAGGCAGCAAAGCAACGCCTTT +GAATCCCAGGGAAGATGACTTCATACCTAGAATTCCCCATCTAGTCAAATTATCAATCAG +TATGAGTGCAGTACAGAACACTGCTTCAAACCTACAAGTTCTCAAATGTTTTACCTCCCT +CAGCTTCTTTCTCAGAAAGCTACTGCAGGATTTGCTCCACCAAAACAAGGGAGCTGCTTC +CCAGGTCTTCTTTCTTAGGAAGCGAGTGGAGGAGAGGCAGAGAGAGCGGGGAGCTGGGGA +GCAGGCAGAGGCTCCAATGGGGCGGGGCAGGAGAAGGCACAGTGGATTACTGATTGCATC +TGTGGCTTTGTTCTCAGAAATGCATTTTAAGGCTCTGGCAAAGAGTCTGAAGATGAATTA +GAACAGATACACAGATTAGAAAATGAAGTTATTAACCCCAGGGAAGCAAGAGTGACCCAT +GAATGGAAATGTAACCAGAGTGTACTTATCACTGCCCAGTTGCATAGCCCCCATTACAAA +AATTACAACTAACTCCACTGGAGGTCTGGGGGAAGAAAGAGAGGGAAAGGGAGGGGACAA +GAGTCAGAGAACACAATCCTGTCTTCCATCATAACACAACATCTAAGATGGGAAAGTCAG +GAAATGTAGGCATATCTAATTTGAAGGAAAATACCAAAATAGTGAAAATAGTTGAAACTC +AGTGTCTCAGGGCAGCAGGGAAGGGACAAAGGGACAAGACAAGCAAGTGCTGCTTCCTCT +CTCAAGTTAAAGAAGAACTACTTCACTTTAAAATTACCTGCATTAATTACTCTCATAAAA +TGAATTAACCTTAAAAAGACATCCATGTTCTGGTTCCTCACAGCCTGGGGAAAGCAGCCC +AGTGGATCCAGAAGCAGAAGACATGACCCCCTGAAGGGAGGCTCCCAAGGACGGGAAGAG +TGAGCTGACTCTGTGCAGAGCCTGGGTCCCTAGGGCAGCCAGATCTGGGGGCTCAAACAC +GCTGTAAAAATAGGATTGTTCACCGCAAAGCCGAAGTGCTGGGCAGTGGCACAGGATTTA +ATGCAGAATGCCAGCACCTAATGTGGCCAGCCTCTTCCACTCCACTCCTGCCCCCTCCCT +CCGATGCACCCCACCCGTCTCAGGCTGCCTTGCAGCCTTGGCACTTGCTGCTCCCTCTTC +CAGACTGTTCTACCCCCAGGAGCTGCTGGTGGCTGGCTCCATCCCACAGTCACCCTTTGC +CTCCCCTGACCCCCACACTCCATCCCCCTCTGTGGTATTGTTTTCATAGCACTTGGCCTA +AGGACCTAAAAACGCCTCCCTGACTTAGTTGAGGTAGAACAGGAGAAACACAAACATCCC +AGTGAGAAGACTAGGGCCAGACCCGGAGAGGACAAAGGTAAGGAGCCAAGAGTAGAAAGT +TCCACAAAACAAAATCGCCAGTGAAGAGAGATTGAAAACAAATCTTGTAATAGTATCCAC +GACCAAACCCAGGGATGGCAAAGCCATCCCCAAACGAATGTGGCTGAGAGAAGGTATTTC +CAGGAGTGTCAGCAGGTGCCCAGGTGGAAGCCAGCAGGTTCTCCTGTGTGGCTTTAAATG +GTTACGAAGGACTGTCAGGACTGGTGCTGTTTATGCGGTTACTCAAACTGGTTATGTTGA +AAAGAAACCTTTTTCTTAATTGCTTTTACCTTGGACCAATCCAGACACTGCCATGTAGAG +CTCAGCAGGGCACGGGCACCCCCACCTGGCTTCCAGGCCCTGCCCTGAGAACAATGATTG +ACCACCAGGCTTCCTGGCACGGATTTATATCCAGGTCTGCAGTGTATTGATCTCATCAGC +AGACACCAGATTCTCGATGGCATAAATCAGGCCCTGCTGCTCTTCTCAAATGGCCTTTAA +AACAGTCCACATGAGTAGCCAAAGGTCAGGACAGACCCCATGCCACATACTGCTCCTCCC +AGGGAGGGGGAGGGGGCTGCACATTTTCTTTGTGACACTGGAGGGTTTTTTTTTCCTTTT +TCAACAAGAATGCATTGTTTCATATAATTTTAAAGTTGCTTTAAGCAAAGCACACACCAC +AACTCACACAGATCTGCCGGCCCTGCGAGTTCTTTCAGAACAGTGGCTCCATAATCATTG +ATGGGTGTTACATTAAGGACCTCACTCTAAATAGTTAAATTAAAACAAAAGGAGAAAAAG +GCCATTTTGCTGGCTTTCTTCGCCATTTCTGAGAAGCAAAGGTATCCCGCTGGGAGCTGA +GCTGTATGCATGTGCATTTTGCCCTGACAGTGTGAAATTGCTGCCCTTTGCATTCAGAAA +GAATGACTTGACACAGGAGCCCATTAGAAAGACAGGGTTGTGAAATGTCACTCTCATTAC +TTACACGTAATTGGGGCTGTTCATGAGGGTGCACGAGCCCACTTTAAATGTCAGCAGAAT +GGAACTCCAAGGGGGCTCTGAGCCCCACACTCTTTTGCCTGTCAGTACTTGTCAGAAGGC +AGCTCTCCCACCCCCAGGGGTCTTCAAATCAAGGCAGGAGATCACAGCAGAGAAAATGGG +AGTACCCAGCAACCACTGTGCATACATGTCTGCGTGTATGTATATATATATGTGGACACA +TGTACATCTGTGTGTATGCATCTGTGTATGTGCACGCATGTGCATCTGTATTTCTGTATG +TGTGCACATGAACCCGCATAGATATGTGCACCTATCCATGTTTGTACATTTGTACACATC +TGTACAGGTGTGTTGTGTACATGTGTATGTCTGCATGTCTGCACATGCATGTGTATGTCT +GTGTGCATACATATGTACACCTGTGTGAGTGCATGTGCATCTGCTTGGATCTCTGCATGT +GTATACATATGTGTATGCATGGGCATCTGTGTATGTGTGTGTATAATGTATGTGTGCACC +TGTGCATGTCTGCCTGTGTACATATATCCATACATATGTATCTGTGTATGCATATACATG +TATGTGTGCACAGCTATATGTGCACATACGTGCATGCATCTGTGTGCGCATCTGTGTATG +TGTACGCAGACATGTATGTGCGCATCTGTGTGTGCATGTGTGTATATGTGCATCTGTGCA +TGTGTCACTCTGTTGCAGAACATACATTCTGATCTAGTGTTGCATCTTAGATGTGAATAG +TGACTGCTGGCAAGTGTCCTGTAAGGCAGGAACCATGAACCAAAATGCCATCTGGGGACT +GTCCAGTCACCCGTGTCTCGGCTCCTTCCTGGGATCAGCTGTCTGGCAGCTAGGGTAGAT +TACAGAGGGGACACCAGTCACTACCACATGGAAGGTGTCAGTGCTTCTGCCAGCAACAGG +ATGCAACACTGGCATTAAAATGCCCTGGCTGGCATCCCAGGGAAACTGAAAGGGGATCTC +TGGTGACAGCTGTGGACTGGCCAATCTAACATAGGCAGTCATTACCTGGACCCCTGACCT +CACTGCATGCAAACTACTGCCTGGGGGAGCGTGTTCTGGCTTATTTCTTATCTCAGGGGT +TTGCCCAGATGGGGCAGGTAAAGCTTAGAGTCTCTCCAGGCCCTACAACCAGGACAGTGG +AGGACACGCACTCACCACATCTTCCCTCCCAGCTGGAAGCAGGCAGCCAGGTGCTGGGAA +ACAGAAGACACCACAGCCCTCACCAACCATGCCCTGCCAGTACCTGGCCACCTAGTATCC +CCACCCTGGGATGTCCTCTGCCCCCAGAAACCCCTCTCCCACCTCCAGTTAGGATGCTGA +TGTCACTGCCTTGCAAACTGAGGATAAAATGGCCTTATCCCATCAGGAATCAGGAATGGG +TTTCAGGAGCTGTCTAGGTCACAAGCATAATAAACAGTTTATTGTTCCAACTTCAGTTTT +CCTAGAATTAAAATGGATCCCTGGAGACCAACACTCCAGCTCTGCAGGGACATGCCTAGC +CCTGGACCTGTGTTGGGCCGGACTCACCCAGCAGGGCAGCTGCCAGGACCAGTCTACTTC +ACCCTCAAGCCACATCCCTGCAGGGGCAAGCGAGCCACAGCCAGGATATCTCAGACATGC +TCTAACCCTCACCCACTTCCCAAACCCCTGGGTGCAGCATGTACAGAATGGGAAACCCAG +GGAGAGAGACAGAGGGCGGTGGGAGTGAAGAACACAGGCATCCATCTATCAGCAATGTCG +GCAGGACAAGCGCTATGAGGATGCACGCAGAGTGGCGGCACGAACAGGGCCCTTCAGAGG +AAGGGTGGGGACCCCTCTAAGCAGCAGCCAGCATGGTAGAGATGCAGACTGTCATGCCAT +TTGTGTGACATCACTCTACTCTTCAGACTTGGATACAGACAATACTGTCTTTTCTGGAGG +GTGTGTGGTGTGTGCATGCATCCTTGGGCCCAAGCAGGTTAGTGCTAGCAAAAATAATCA +TCTTCCACTGGCCTAATGTTGACCTGCTGCCATCTCTAAGGGGGCCAACGGTCTCCCTAC +TGGACACTGGCTCCCAGGCACAGTGTGGGGTTGTTCTGGGAAGTGGCTGGCCAGCCCCTC +AGGGAGGACTGTGTTAACCCTGCGGCCCTAAAGGGATGCCTGGTGTCATGTCTTTCAAAG +GTGATACTATGGTCTGAATGTCTGGATTACCCCCAAATTCAGATGTTGAAATCCTAACCA +CCAATGTGATGGTTTCTGGAGAGGGAGCCTTTGGGAGGTGACTGGGTCAGGAGGGCAGAG +TCTTCATGGAAGTAGTGCCCCTATAAAAGGAGTCCCAGAGAGCTCCCTCACCCCTCAACC +ATGTGAGAAGACGCTGTCTATGAACCAGGAGGAGGGCCTTCACCAGACACCAAATCTGCC +AGCGCCTTGATCTTCGACTTCCCAGCCTCCGGAATGGATAAATAAATGTCTGTTTTTATG +TCACCCAGTCTATGACATTTTGTTTGAGCAGCCTGAGCTGACTGAGACAGTGGCAATTCA +GGGGCTGCTGGCACCCAGCAGAGCTCAGCACCGGACAGAACCCAGCCAGCAGAGATGCTT +CCAGAATGCCAAAGGTCGGTCACCATTTACACTGGTAGCGCCTTTGATATGACACTAAAA +CTGGTGCTTCGGTCCCCCAGAGCTTGGCTTGCAGGGAGGGCAAAATTACATAAAAGACAT +TATATAGAAAAGTTTTGCTTTAAGTGGACTTTATTTGTATTCTTAATTTTCCACCTCTTA +TAAAACTGTCCTACCTTCAAAAATAATTCCAAGGGTGCTTAACTCCACAAACCAAATGTA +AATTAAAATAAAATACCCATTATTGTCCACAAAGCAAGCTGAAATTTAAAAGTCTGCTGC +TAGTTAGTGCTGGGAAGGTGTGGGGTAAAGGACTTCTGGGTACAATTCTGAACTATCCAG +ATGTCTGCACACTCTGATCCCCTGGCAACTCTTGGGCAGCAAACTATGTGTGCACAGCTA +CAGGCGTGCAAAGCGACACGTGGGAAGACCACCCTGCCATGACGTGACAGTAAAATGTGC +AACCAAAGGGGATGCTCCTCAATGAGGGGCTGGTTAACAGTCAGGCAAGGAAGACAACAC +CATTACAAAGACTAAAGCTGGTCTACACGAACTGCCTGTGAGCCCATCACACCGAAGACA +TGTGTAGAGCAACAACACGCGAGGCGCGACCCACCTGTGTCAACAGAGGATGCGTCAGTC +TACACACAACACATACACACACAGCCACGGACACACAGGGACATGCACAAACACCAGGCA +CAGACTCACAAGAACATACACTCCTACACACAGGGACACACAGATACCAGACACAAATGC +ACACACATGAACGTGGACAGACAGCCAACTGTTAACAGTGGTCGCTTATAAGGAGGAGGA +GGAGGAGAACAACCAGGAACTCAAGTTTTCTTTGTTTTTTAAAAAATGAATCATACTTTT +ATATTGCTTCTGTAAAAAAATTTAATTCATGAAGAGATTATGTTTCACCCATGCTACACC +CAAGTCAGTAGACCAAAAATTGAAACCCACCACATTAGTGTATGGAGCTGTGCATAATGC +GATTTTTCACATGCTAATCCATTTCTTGGTTTAGGTGACTATTTCTTGCCATACCTTTGA +CCTTTTTTTTATTTACATAAAAAAATGAGAAGTGGCTTCCTTTCCCCATATATACTTCGT +GCTTTTTGTGACAGCAAAGTAAAAAATAACAGAAGGAGCCAGTCCTCCTGGGCTCTCACA +ATGGAATTCTCTTACTGCTTAATACAGCACAGAATGGATAAAATTGTCCCTGCTTTCAAT +TACCTTATAACTAAAGATTCCAAAATATTTTTTATGAAGAGACTGACAAAAAACAAAACT +CAAAGACAAATGACTTAAGGGAGGAAAAAGAAACCAGCAAAAAATACTTGTAAGACAAGT +GCCAATTCCTAATAAATAAAGTGATTTAACAAATGTAAGAAAACAGAGCTCCCACCCCAA +TGGACCAGATAATATATCTAGCCAATAAGCACAGAAAGTGCTGTCTCCCTGGCAGTGATG +CTGTGCTAATTAAAGCCGCCCTATCTAATTGGCAAGATGTGCTCTCATCACGGTCCCATG +CATAGGAACCATGAAGGTCTAAGCTGGCAGCAGGACTCTTTAAAAGCCAGCAGAATAAAA +AACCTTGTGGGGGCTCATTCATGATACTTGAGTAATATGAAAATGATGAAGGAAAGATGG +GGTTTGACTTTTGTTTTCACAAATTAAGCTGGTTATTTCCTTCTCCTCTGAAACTGAAAA +TGCATGGCTTGGAACGGACCAAAATTAAGATTAAACACAAAATGGCCCAAATCTGAGGAG +GGTGACCTGGAGAGCCCTCTTATTACACCACACCTTACCAGCCACCTTCCTGCACCCTCC +AAAAGAAGAGAGTAAGCTTTCTGGTGCAGGCACCAGGGGCCATCAGCCGCGGAGCTGCCA +CAATCCCAAGACCCAGTGGGAGGAGAGGCCGAGAGAGCAGGGAAGAATAGGGGGAGCTGG +GACAAGCAGTGGCAGAGCAAGAACAGAGACAGACAATCACTGTGGGTGCCCAGCACCCAC +CTCCCCATGCCGGGCCCAAGGGATGGCAGCCAAGTCTGAAGCTTTGCCCCACAGGATATC +AGGGACCAAGGGACCAAGCAACCAACCACCTGCCAGATCCAACTGAGGCCTCTACACATT +ATCAACTCTGCTCAACTGAAATTACAGATCATGAATAAAGTGGTTTTACCTGTATCTTAT +GCCTCTTGAAACTTTCCAGTCATTTCTAGAAAGACGTCTTCAGAAATCTTTGCTGTGAAA +ATAATGGGAAACAAGGCTATTTAAGCCCTTAAACTGTGCATCCACTTAAACTCAGCAACA +CTCCTAGAAAGGCACTGAAAACAAATTATTGTGAGTTTAAACCTTCTAGACTTCCTTAGA +CGCAGGATCAGCTTGGCTTGCATGTGCTGGGGAAGACAGCACTGGGGCAGACAGGAGGGA +GGAGCTGTGCAACCACCCACCCACGAACAGAGGGGAAGGGCAGCCCAGCCCGTTACCTGG +TGCTAGAGATGAGCCCCAGGACCCGACCAGGTGTACTTTCTTGCACAATAAGCCATTCCA +GTTAGCAGAGTCTGTGAACCAAAAAAGTACTATCTAATTGTCTATTAGCTCCAGATATGT +ATCCTTTAAAATTCATCTTCATGAGGCAAAGAAGGAAAAAGCAGAAACACATATGGCATA +ATTACAAGCACTAAAGAGCTGTTCATCTTCCTTTATTTTTGGATGGCTGGTTTTCAGCCA +AACAGAACGGTGTCCACCGTGGTGTGGCAAGGTTCCATAGCATGGCTGTCACTCCTTTGC +AGTGTGGGAGATCAGTCTCAAGACAGGGATCGTGGGGTGCAGTAGCAGCACCAACAATTA +GATCAAGAGAATCAGAATCGCAAAACCAGAGCCACGTGCAGGACTGCAGACGCTCAGGAG +CCGACGCTGATCCCTCCATGATTCTATTAACACAGGAGCCACGTAATTGTTAAACCTTGG +AATCAGACTCCAGCATATTCTGTGGTGAGGAGGGTTTCTTTTTTGTTTGCCTTTTGCTTT +CAGAGCTTATATGATCACGGCTCTTTTTTTGAAGCCAGCTGGGAAGGAGGCGGCTCTCCC +TCCTCTACAGGAGCCCCCGTCCCTCCCACCCAGGCCCCTCACTGGACGGCTCCCTCCTCT +ACAGACGCCCTGTACACCCCTCCCCAGGAAGCAGAACCTTAGACACGGCCATCCAGGCAC +ACAACATCCGGTCCCCCCACCCCTCGGGGCCGACACATCCTCTGAACCCTGAGCAGGCAC +CTGAGGTTAGCAAATGAACCGCGAGGGCAGTGATCAGAAACGATCACGATTCATCAGGCC +CCACCGTAGTGGAGCTTCCAGAGACTGATACTGGGGTCTTCCCTCCAGCAGTGGATGGCT +CTTACGGCCAATTTTATAAGCAAAAGTAGGTTCACATGAGCAGCTATGAGAATCCTGGAA +AAGGCCACATCCACCCAGGACCTGACACCGACATTTCCTGTTGAAACTCCTGGGGCAGGG +CTGAGCATTTGGGCACAACTGCTGGACAAGCAAAGAGGGAAAGTCCACGCTACTGTGGGC +ACCTGCAAAGTGCCACATCACTTGTTTCCACGAGGCCTTCCTGTCACACGGGAGGGAGAG +GGGACAGTGGCCGCCCAGAGACTGTGCCAAAAAACAGTTGAAGGCAACAAAGGCAGAGAT +TCATACATAAATAAGAGGCTTAGGTAAATAATGTGAATATCACGGATTTTAAAACTAAAA +AACTGGCCAGGCACTGTGGCTCACGCCTGTAATCCCAACACTTTAGGAGGCCGAGGCGGG +TGGATCACTTGAGGTCAGGAGTTCAAGACCAGCTTGACCAACAAGGCAAAACCCCGTCTC +TATCAAAAAAAAATACAAAAATTAGCTGGGTGTGGTGGTGCGCACCTGTCATCCCAGCTA +CTTGGGAGGCTGAGGCAGGAGAATCGCTTGAACTCAGGAGGTGGAGGTTGGAGTGAGCCA +AGATCGCGCCATTGCACTCTGACCTGGGTGACAGAAAAAGACTCCGTCTCAAAAAAAACA +AAAAAACACCTGAAAAACTTCTATTTTTTAGAAATGAAATAAGCCTTTGTCACTTTAATA +AAGACCCAGAACTGCTCATCCTGTGGTTTAAGACACGTATCATATTCACGGTAATTTTGT +GGCATCCAACAACAAATGTCAGCAGGTCTGGGTTCTCATCTCAATTGCCTCCAACAACTC +CACCTGAACACCAGCATCCTTGTGTCCTGCCTCCCAGCTGGGGGTTCATATCTAGCCTCC +AAAAACAGCTGCCAGCCCCAAGGTTCCTGAGTGGGAACACACTTCCTTTCTTAGTGAATT +GCCCAGGCCCCAACCCCGCGTTGCCTTCACCCTACACATACACGGTTTGTTTCTTCTTTC +TCAGCGTGCAACCCCACAGTTATGAGTTACCTGGCTTAAAAATGCAAACCCACACTTCTC +ATGTAATTACTCATCATGCTGTTTTAACTCATATCTCCCAACTCCTGACAGCACAGGTAA +AAAGAATCCAATGGCCTGTTCATCAAAAAGCAATGAAATTAATTAGGAGAGAGAAGCATT +TCCCTCTCATGGCCTTCACATCCTCTCCTGGTGCACCCCCTCTAGTGCAGGAGAGTGTGG +GGCTCCAACGCCCAGGCCTTGCGAACAGGTATTTAGTGGTCGCTGATGGCAGAAGGACAG +AGCCACTGGCAGCGCCTTCATCTGGCCTCCATCCTGCAGACATGACCTCGCCTTCTGGGC +GTACTCCCTAAGCAGGGACCTGGTGTTCTTCAGCACACAGAGAAGACAAGTGGGATGAAG +CAAGAGCAAGGGGCTCTGCAATCAGAGGAACCTGGGTTCCAGTCCTGGCTTCTCCAAGTT +GTGTGTTCCTGAGGGAAGTTACTGAGCCTCTCTGGGCCTCTGTTTCCTTATCCAAAAAGT +GGGCATACTAATACTGCCTGTCTCATTTGGTTATGAGGATCCATGACTAATCAGTTAATG +CTTCCTAGTGCTTTCCTAGGTGCCCGATGCTGTTTAAGCACTGGGAGGCATTAACTATCA +TTCTTACCACTTGTGAAATGAAGCCAGTTATATCTGCCTAGCTAAGAAGACTCAGAGAGA +TATAACAAGCAGGGTGCAGCTATTAGCACATCTAACAACCCCTACTGCCAGGGACTGTGG +GCTCCACCAGCCTCCTCCTGCACACACGGGGGATCGGGGCTTCCCCAGGTCCACATAGAC +TCCTGGAAGCAGGGCTTAGGAACACTGTGACAGGCAGCACTGCTGTGGCTGTGGACGGGG +AGAGGGCCGTGAGCCCCTTCTGCTCAATCTCCTCATCCTGGCCCAGAAGCAGGTAAGGAA +GTTCCGGAGGCAGAGAGCAATGGGGGACCTTCTGCTGAAATTGGCACTGCAGCACACACC +TCGATGGGGTAGGCATGCATATTACAACACAATACCATTACACTCTGCTGAGCAGGGCAC +CCATGAGAAAGGCTGGCTACAAAGTACACAGACAGGGCCCGGAGGACATGTTTCCGCACC +CTGCTGGGCAACACCTGCCAAGAAGCTACATCCAGAATCTCTGATCCAACAGTCCTCTAC +CAAGAATTCAGTATGGATATACCCCATGTGTGCAATATGACTGGAACGAGGCTATTCAAT +AGGTAAACTCCAAAGACACCCAGAAGTCCACCAGTGTGTGTGCGTCTATGTGCATGGGTA +CACACAGATACAGCATAGAACGTTTTCTATACAAATTATTGCACATTCCAGAGGATGGAA +TACTATGCAACTGTTAAAAAGAATAAAGCTGCAATTGTATGAAAGGGCGCTGTTCAGTAA +AAAGTAAGGTTCCCAAAAATGTGAGTAGTATGTTTCCGTCTGTGCAGGCACATGGTGTGT +GACCGTGTGTGTGCGTGTGTGTGTGTGTGTGGGTGTGCACACAGGCTCATCAGAAGGATG +ATTCAAGAGATCACAATTTAATCAAGAACCTGCTGGCAGCAATGCCTATAGAGAGAATTT +GATCTGCAAAAGGAGTGTGCTTCATTTTTCATGATTTTGATTCTTTAGAACTATTCGAAT +TCCTTCCTTAATCATGTGGTTTTCTAACTAAAATATTTTAAATCTGATATCAAAAGTAAA +ATACAGTAATTGTAGAAAATTTGAAAAATTCAAGAAAGGCAAGAGAACACATTGCTGACG +ATCTCTAAAAAGGTTACACAGGTTATAACGCTGGTTAAAGTAAGATCCCAGCTCGGGTGT +CTCCTGTACTAACTTTACTAAGAGGAAGATTTCATCAAAATGGAAATTTTTAAGAACAGC +AGACAGACATGACATACAGTTCTGGTCTTTCTGGCATTTTGGTGAATTCCTCATTCTAAG +AAACTCTGACTCATTCACTCAACAGTCACTACTGGAGGGTGTGGGGTGAAGGTGAGAGTC +AGATATAGACTGTAGACCCCCAGCCCCTGCTTTCTGGCTTGGGGAGGGCAGGCCACAGCA +ACCGCACAGGACGGTTGGGGGGCCCTGCTGGCTCTGTAACATGGGAAGTGGGACAGGCAG +GCTGGGAGCCATGCAAGAGGAGACCTGAAGTCCAAGAGAGAGGCTGGAGCCTACAGGCTG +GTAGAGGAAGAGGGCCCGCGTGGGTCACGTCCAGGTCCTGTGTGTCCCTGCCCCGAGCAC +CATGCGTGCGCATCCCCGTGCCGTTTATTACGTGGTGCCCTCAGCAGCCTGTCACGGCTG +TGCAATATTCCATAATTAAATATCATAATGTGGGACATTCCGATCCTTTCCAACTCTCCA +CTTACAATTCATTTTTCTTTAACCACCAGCAGTACCCGGCCAAGAATCTTTTCTGTCTGG +AATGTTCACAGTGATGTTACAGAGGTCTAGGCACCACACAGAGGGCACTGGGAGATGGGC +ACGGGGGAGATTCCATGGTTCCATCATGTCTGTCTGCTGTTCTTGAAAATCTCCATTTTG +ATGAAATCTCTTAATAAAGTTAGTACAGAAGACACAAGTGCTGGGATCTTTAGTAGTCGT +TACAACCTGTATAACCATTTTAGAGACTGTCAGCAATGTGTCAGCAATGTGTTCTTCTCT +TGCCTTTCTTAAACAGAGGCTCAGGGCTTCTACTGATCAGGCTGACAGGTTTGCTTCCTT +TAACTGGGAAATAATCACACATAACTTCCATGATTTATTTTCATTTGACTCTCTTCTAAA +ACTTTCAGTTAGTTGAGCTGAAGTCATTTTTGCAAAGTAATACTATATTTGCTATAAAAT +ACAAGTCACCTAGCTCAAACTTTTTTTTTTTTTTTTTAAATTGAGATGGAGTTTCACTCT +TGTTGCCCAGGCTGGAGTGCAATGGCGTGATCTCGGCTCACTGCAATCTCCACCTTCCGG +GTTCAAGTGATTCTCCTGCCTCAGCCTCCCAAGTAGTTGGGATTACAGGCATGTGCCACC +ATGCCTGGCTAATTTTGTATTTTTCGTACACACAGGGTTTCTCCATGTTGGTCAGGCTGG +TCTCAAACTCCCAACCTCGGTGATCCGTCCACCTCGGCCTCTCAAAGTGCTGGGATTATA +GGCATGAGCCACTGTGTCCGGCCAGCTCAAACATTTTTTATGCTTCTTTCAAGTCTATTA +GAAACCTTAATTGCTTCTTAGTTTCTCCCCCAACTATGGAGGAAGCATATTGTGATAGCT +GCAGTGCCGGCTGTGAGGCCAGCTTGCCTGGTTCAGATTCCCATGCTGCCACATCCCAGC +TGTGTGACCCAGAACAGGCCTCTGCCCCTTCCTATCCCTCAGATACTTCCTTAGCACCTC +CCCTCCCTCTGCTACTCCCTCAGTACTTCACCTCCCCCGGCTATTACCTCAGCACCTCCC +CTCCCTCAGCTACTCCCTCAGTGCCTCCCCTCCCTCCACTAATCCCTCAGCACCTCCCCT +CCCTCAGCTACTCCCTCAGCACCTCCACTCCCTCAGCACCTCCCCTCCCTCAGCTATTCC +CTCAGCACCTCCTCTCCCTCCACTACTCCCTCAGTACCTCCCTTCCCTCAGCTACTCCCT +CAGCACCTCCACTCCCTCAGCACCTCCACCCCCTCAGCTACTTCCTCAGCACCTCCCCTC +CCTCCCTACTCCCTCAGTACCTCTCCTCCCTCAGCTACTCCCTCAGCACCTCCCCTTTCT +CAGCTACTCCCTCAGTACTTCACCTTCCCCAGCTACTCCCTCAGCAACTCCCCTCCCTCC +ACTACTCCCTCAGCACCTCCTCCTCCCCACAGCTACTTCCCTGGGAGAGGGTAAGACACA +GCCCTACCACCAGAGATGAGACTGCACAAATGAGGACTGTAAGGCATGGACGTTAAACAC +AATGTTACAAACAACCAACAAAATGGCACTATCCCCACAATGGCGGCCCACACCAAGGTG +CGGAAAGGTCCAATCAGAATCCCACAGAAACGAGCAGTGCAGGGGCAAATAGGTTTTCCT +AGATCAACGTCAATCTCCATTAAACCATGATGGTTTACTCTGTGATTTATTCCTAAATTG +AAGTTTCTTTCTAAAGCCCACGACCACAACATTAGCTTTTACTACTTACCTCAGCTCAAT +GAGTCTGAAATGATTTAAATCCAAGATGCTTCCGTCCCGACTCCAAATTCCTTCGAGCTC +TTTTTTTTCAGAACCTTGCACCCTTAATTCCTGAGTGTCTCCTTTCTCTGACCAGGACCC +TTCTCGAACCCTACTAATTGCCTTCCTCACTGTGTCCTGCCTGGCTTTGGTCTCCTGGGC +ACCCTCTTCCTGCCCTCCCCCACCTCTGCCCAATGTCCCCCACTTCCCTCACACCCACGG +TTCATACCACCATCCCTCCTGTGAGGCCTCCACCTGGCTCCCGCTACCTGTAAGGGAATG +ACACCACATTCTAAGAGCTCCACCTTCTTACGGCCCCTGTGCCCCCGGCCTTCAGTCCCC +CTACACACAGAGGGGACTTACAAGGCATGCTTATTTCTTACAAGGCAGCTCGCATCACAC +TATTCTCTTGCTCCAAAGCCTCCTGTTTCTCTCCAGGGCTTGCAGAGGCAGGTCTCAGCC +CCCAATCTAGTGTCCCCAAAGGAAGCCCTACAACTTGCTAGGTGTGCATTTTCCCCTCTT +TCTGTGGAACACCAAGAATACACCACCTATCTAGACCCAGCCCCCCAGATATTCTGATTT +AGCAGCTCCCTAGTGAGGCCAGGGTCTGTCTGGTTTTAGAGCAGCCCATGTAACTGGCAG +CCAGGACCGAGAACTGGCCTGCATCCACCAGATTTCCTGCCTTGCCCAGTGTTACCCAGG +CCTTGCCACCTCCCCTAGGTATGTCCTGAGTCCATCCTTGACACCCACCCACTGAAATCC +TGGCTGTCCACTGTGGCTCAGCTCGAAGGCCAGGGCAACCTCAGACCTGCCCTCTGGGAA +CAGATGCCTCCCCTCAGCTGGTCTTCATTCACGGGGTCTCCTGGGGGAAAATGTAAGCAG +GAAGAATAACTAACACCCGCCATAAGGCAAGGGTGAGGAAGTGACTGTTCTACTGGGTTC +TGCGAGGGTCAGGCTGTGAGTCACCTGGAAGCAGCACGTGGCCCTGACATCTGGGAAGGG +GCTGCTCACACCTCCCATGTTCATAGCTCCCTGGCAGGCTCCTCACTAACCCTCGTATCT +GACATCTGACTGAATCCCAGTGTTCAAGAGGCCTGGGCAAGGACAGCCTACAAGCCCGCT +GCTTTGACATCAGGGGCAGGAGTCCTGAAAGCCTGACCCTGTGGCCCCACTGGCTGTACA +TCCACCCCCTCCCCCAGTGTGCCCCACTGGAGACAGGTTTTACAGCACTGCTGGGAAGAG +GAAAAACAGGCTCAGAAAAATGCAACAACCGTCTAGAGCCACTGGGAGAGGTGAGATGCC +CTCCCGGGTCCTGCAGTGACCCCAGGACCATGACTGGCACAGTGCTCTCCAGCTGTGCTG +AGGCTCCACCTGCCCTGAGCCAACAGCTTCCTCCTCCAGGGACACCAGGGCAGAGACAGG +CCCTTCAGAAACAATGGCTCCTTCTCTTTGCCAACTGCCAGCAGTGAAGGCATCACAGAA +TCTGCCAGAACCATCCAGAACCCTGAACTGGTTCAGGACTACAGGCAGCCTGGGGAGATG +CCCTGCACTCAGAGGCATCCCTAGTCCCCACCAAGTGTCCGCAGGGGGAGCGCATGCAGT +TTCTCCAGGGGACTGGACCTCCTCCAGGCCGGGATCCTCCTCCCCTGCTGCCCTCAGACT +CAGCCCAGCTGCAAAGGCGCCAGAGGCCTGCTCGTTCTGCCACGGTGCAGGCACGGCATG +AGGGGATAGGCCCAGGAGCCTCAGGACAGGCCCCAGTCCAAGTGGGAATTTCTTTTTTAA +GTCTCAAAACCACAAAATGCCACTTTCCTTGCTTTCATCTTTAGTGATTCTTTAAATATA +TACACTACAATTACAAAGTTAGACCACCATGACCACAGCTCGTAACCAGAATAGAGTCAA +CAGGGAACCTAGTCAACAGGAGGCTCTCCCTCACTATCCGGGCCTCCTCCCCAGGACATG +GCTTTTGCCAGCCTTAGCAACAGCGTGGCAAACCCACCAGAGAACCACAAGCTCCAGCCA +GAGCTCTGCGAAGGCCCCAGCTTTGCCTCACTCCAGGCGGGAAACAAAAGGATGTTCGCC +ATTTCATCATCTGGGGCTGTCAGTTCCCGTCTCAGTACTGACCTTAAATGCTGTCTTACC +GTCGTGCGCAGACACCAGGTGCACGCAGCCTCGACCTGATCTACCAGCCCCCAAAGCCCC +TCAGAGGCCACAAGAACCTCCCTCAACCTCAGTATCAGAGGAAGCAACTTCAACTAAGCT +CATAATTATTTTAAGACTCTCCTACATCTTAACCATATTCAAACCAAACCAACTCACTTC +CCATCAACAGTAGACCAAGTGGTCACTGTGGGCAGGTGACAAGCATCACAGAAGTGCTAA +AAATAGACAATGTGACAACCACAACACCCGGCTACGATGGTAAGGAGCAAACACTGCAGG +CCACACCTGTGCCCTAGGTCTGTCCCCAGCGAGTTCCCCCTTTGCCACTAAGACAATTAC +TGCCCATATGGATGGCCAGAATTTCAATCAATTTCTATTTCCAAATCACCAAATGACCCT +CTAGCTGAATGTCACAAGCCCAGTATTGGGTCAGAGGTAGATACACTCTACTCTAATGAA +TTATAGTCAATCCCCACGTTCAACTCACTAAATCCATCCTCCCTTGCAGTGCAAGGGAAA +TGATATTTCTTCTCCTCTCTTCCAGATGCTTCCAGCCCAAGTAAGGCAGTCCCTCAATTC +CCTTCCTGGGGAGTCAGAAGAGGGGGGCAGCCTAAAATGATACAGTCAGTCACTCAGGTC +CATCCAACCCCAAATAGCCGTAGATGCCAGAAGAGGGTCAAGTGCATATGGACTAAGGAG +GCGGTGTGACCCTGGTGAGATGCCTGTATCAGAAAACCACAGCCCCTGCCTCCCTGAGAC +AGCCGGGGCCTGGGGAGTAACCCCTGCCGTCCTCTCAGTGTGAAAGGAGCCCAGGTAGGA +ATTCCCCACTGAAGGAGTCAAGCAAACCCCCAATATTTCAGGATTCACTCTGCAGCACCC +AAATGGGAACAGATCTCACTCACGTTTCCCTGCACTGCTAAAAGGAACCTGGTCCTATTA +ACCTGGAACCCCCTCTCCACCCCCCGGTCAGCAGCACCTGCAAGTGGCATTTAGTGGGGC +TGACTTCAAAGTGCCCAAGCCTACGGGGCTACGGCCCTGCAAAGTCCCATCCCGGTGTCT +GTCCTTCCAGCAAGCAGCCAGCTCTACAGCATGTGGGGGTTCTCATTTTCCGAGCAGTGT +GTCACCTTCCAGATGATTCAGAATGTGTGCGACGTGGCGGGTCACACGTGGGGAGGAGCT +GGTGAGTCACTGTCACTCATTGCCCCCCACACAGTCACCTTCCAGGTCTGAGAGCTCCAG +GAGGGGGGCTACCTGGCCATTGTTCTGTCTCTCGTAGGGCCCAGGAAGGAGGTGTGTTTC +CCCTAGGGATGCACTCACCACTAGGGTGACCACCTGTGGAGGGCCCGCCTGGCCCTGAGG +GGTGGACTCTGCCCTGTAGGCGTGGGTGGCTTAGGGCTGACCTGAGACGCTGGCTCCAAC +ACCCAGGCCCTTCTCACCTGCGTGTGTCACTGAGGGCCTGCTGCTGTCCGTCTGACCACC +GCTGACCTGTCATGGAGGGATACGGCCCCCACACTGAACAATTCCCTGGGCAGGCTCTTC +CCAACCATCTCAGTGGTCACAAGTTGAGGACCACCACTGGCCACCAGCTCCAGGCGGCCC +CCGCCATGGCCCATGCAGCTTCCTTCTGGGCCTCACATTCGATGCTGCCCAGCACTGCCC +AAACACAGTCCCTGGCCCTGCAGGGGAACCTGAACTGGAAGGACGAGGGCAAGACCCATA +TGACCTGCCAAGAGCCCAGTGCCATGCCCCAGCCACCAGAGAGGGTGCCAGGCGGCAGCA +GAGGGGAGGCACACATCCTCCATTGCAGCCAGCGTGGATCTCAGGGCTACAAATAGCCAG +TCACAGGAACTCAGAACCACGAGGAACCGGCCCCTTCATCACAGGCAGGAGGAGAATGAG +GCACAGGCATGGAGCCTGCTCAAGGTCACGGAGCCTGCTCAAGGTCATGCAGCGCAGGCC +AGCTCCCAGCCACTCTGCACACGGCCTGGCCCACTGTCTCCAAGACTGCTTTCTCCTGCA +CCAGGGCAATGGCCCCCGGCCCCACCTACAGGACCATGGTGCACACGGCCAACCCACCTC +CAGGGGCAGGGTGACAGACATCCCCCAGAAGAGCAAAAAACCAGATCCCAGTATGGGCTG +GCCATAGGGAAATACGCAAGAAAGCAGCCACTAGGTCCCCATCTCCACCTTGTCAGCAGC +CAGCGCAAAGCTTCTCTAGGGCTCTGCCCCCTGGGTCCCTCAGGGCCCCTGGACCCTGCC +AACCACACCACTGCAGGCTCCGCATGACTGCTCCAGAGGTCCAGAAGACAGACAGGATGG +ACCTAGGTCCCTGTGGGGGGGGTCTCCCCTTCCACGCTCACTCCTGGCCTTGGGTCACAG +GCCCACTAAGCGGTTCGTCCAAGAGTGCGAAGAGTCAAGCACAGCCCCCAGCTCCTTCCC +CAAATGCAGGTTACCCACGGGGCAGCCTGGGCATGGGCACTGGACAGAAGTGGCATGTAG +CCTGGCTCTCCTAACCTCCCTGCCCAGTCAGCCCTCCCAGACCCACCACCAGGAGTTGTA +CCAGGCCGGCGGCCACCTCGGCTGACTCTGGATGCCAAGAAGCCTCTAATCCTAGCTTCA +CCCAAAGCAGACGACATCTAGGAGAGCATCGACATCCCCATCAGGGTGAGCGCCTTCTTG +GGGCCAGGAGAGGGGGCTGTGAAGACAGTAATTCAGGTCACCCAGCAACACTGTCACCAT +CCCTCTTTTGCAGCTAAGAAAGCAAGGCTTGGAAACTTCCGGAAGTCATATCAGTGTTGG +GGGGTAGGGGGCAGTGTCTGACACTACAGGCATGGAAAGCAAAGTTCCCCGCCCTGCATC +AGAGACAAACTCAGGTGGGCCAAAGCAAGTTCCTGAGCACACCTGGGCTGAGCTGTGCTC +ATTCAAATCGGTTTCTTAACAGAATCTCAAGTTCATCTCAAGCTTGGAGCCTGGTGAGCA +CTTCATGAAGAGCAGGTTCCTGGGTCCCAGCCGGGTGACAGTGGCCGAGGGACGTACCCG +ACCTCCAGAAGCCCGGGAAGCATGCTGTTCCAGAGAAGTGCACGCTGCTAACAGCCCATT +CCAGAGCGCATGGTGCAATAATTTTTTGCTAGCTTTAAAAAGCAGCACAAGAAAGAAATT +ACGCGGTTTGCAAACTGAAGTCTACATGGTGGATGGAGTGGCCAGTTACGTGCTCAGAAG +AATGCAGCTGTGGGTTTCTGTTTGGGGTCAAGCTTTGCCAAATAGTAGCACTCTGAAAAT +GCACATAACAAGAAAACCTCATTAAAAACTCTGTAACCCTAAAACCTGTATCAAAGCCTC +CAAAGCTGCTGCTTAACCCTGACGGGCAGCTCTGTGGGTGGGAGCGGTCACAAGCCTGGC +TGAGGAGGACGGGCCTCAGGCTGGGATGGCAAGTCATGCCCAAAGCATCTGCAAATGACA +GAAAGTTCTGGAAATATTTCACACAGGGAAGGGAATTACTGGACGGTCAGAACATACACC +ACAAAATTTCAGAACTAGGAGGAAGTTTTCAGCAATACTCTCCCACTTGGGGCCAGAAAC +TCCAAGCATCTGTCCCTGCTCCCCAGCAGCCAAAGAGCAAACCCTCCAGACAGCTCCCCA +ACCACATACACACTGTGTCAAGGGGCCTGGACCCCACTTACTGGGTGAGTTAGATGCCCT +CCAAGCTTCAGAGGGAGACAACTGACTGTGACTGCCTCTCTAGGGGTGGCTATTGTCCAG +ACGCAAAACCCACCCAGGGCAGGAGCCTGCAGAGGGGCAGCAGCCAGGCTCGGAGGACAA +ACAGCCAACATCTTCCCAGGCAGGGAAGAGGACCAGCCACAGTTACTGGGGAGGGGGAAA +CTGGCCTCTGATGTCTACAGAGTCTAACAGGTGTATTTCCAAGGCCTCAGCAACCCCGCA +AGCTCAGAGAGATGCCCTGCCCAGGGATGTTTATCTCCATGGTGCCTTATCAGTAAAAAT +CTGTCATCCAAATATGCACCATCAGATGGGCCGAGCGTGGTGGCCCAAGCCTGTAATCCC +AGCACTTTGGGAGGCCAAGGCGGGCAGATCACCTGAGGTCAGGAGTTCAAGATCAGGATG +GCCTACATGGCAAAACCCCATCTCTACTAAAAATACAAAAATTAGCTGGGTGTGGTGGCT +CGCGCCTGTAATCCCAGCTACTCAAGAGGCTGAGGCAGGAGAATCGCTTGAACCCGGGAG +GCGGAGGCTGCAGTGAGCCAAGATCATGCCACTGCATTCCAGCCTGGGCGACAGAGCGAG +ACTCCATCTTGAGGGAAAAATACCAAAAAACAAATAGGCACCCATCAGAAACAGGTTAAA +TTAACAATAATATTATAGCATGCTATGCCGGCAGTACAATCCACACAAGTCGATGTTTAT +TGACAAATACAGATAAACATTCTATTAAATGCAAAGAGGAGAAGATAAAACAGCACTTAA +GTGCAAGCTTACTCATGTAAAAAACCCAGTCATAAAAGGTCACACCCAGGGAATGGCCTG +ACTGGCACGTTCCAAGCTCACTCCCAGGCTGACTCCTAACCCTGGCGGCTCCTGCTCCTG +CTCCTGCGGGTGAGCCACCCGGGGCACACCCAGGGCTGGCTAGAACACCACCTGCAAATG +CAGGTAGAGCAACCTCCAGGAGGAGGGACACCAAAATGCCAGAACTAATTCTGGGAGGTG +GAATTTTAGGGGCACTTTCAATGTCTTCTTTGAATTTTCCTGTATCTTCCAAATTTTTTT +ACTGGAGGCATTTTTCAGTATTGTTCTCCCAAACAAGAGCAGTTTCCCTAGATTCTCTTT +TGTTTTTTGGAGACAGGGTCTCACCCTGTCACTAAGGCTGCAATGCAACGGTGCAATCAT +AGCTCACTGCAGCCTTGAGCTCCTGGGCTCAAGTGATCCTCCCACCTCAGCCTCCTGAGT +AGCTAGGACTACAGGCGTGAGCCATCATGCTCAGCTATCTTTTTATTTTTTTGTAGAGAT +GGGGTCTTGCTATGTTGCCCAGGCTGGCTTTGAATTCCTAGGCTCAAGTGATCCTCCCAC +CTTGGCCTCCCAAAGCCCTGTGATTACAGGTGTGAGCCACTGTACCCAGCAAGATTCTCT +CTTTTGATGGTTTCACCTCAGCAAAAAAGAAGGTGGCCCTAAAGCCCCCAGAGCACATTC +CCGCCTCCTCAAGGACACGTTCCCAGCCCCTCCCTTGGCCAGACTGGGATCCATACAGTC +AAGGCCCCAATACGAGCTCTGGTTCATCTATGCTATCCTCATCTCTCTGTGTCCATACCT +CAGTGTACCTTCCCTTCTGTGCTGCTCTGCCATGACAAGCCCTGACCAGTCCATCTGTTC +CCCCAGGAGAGGCATATTTACATGGCACAGGAGCCTGGTGGCCCAGCTGCACCCTCTGGG +CCCACCCTTACCAGCTATGCAGCCCTGGAATGGCCACTCAACCCTCTGCCCCTTGGCTTC +CATCCATAAGACAGAGTTGGCCACAAAAGGTACTTGGATTATTTATAACACTGCTTGGCA +CAATAAATGTTAACCACTAATATAAGTAGTATTATATAAGTGTACTACCACAGAATGGAT +TGGGTCATTTTTACTAGATAGTGGAACTGTAACCCTGACTAAGCCTGGAGATCTGGGGAC +AGGACCCTGGGGAGTTGGGAGCTGAGATCTGAAAATTCAGGATGATCAGGGCGGCCACAG +TAAGGTCCTAAAACTGCCTGAGGCTAGTGTGAGGGGCGCCCTCCAGCACTCTGTCGTAAG +GGCAGCAATAAAACCACTGGCTGCATGGCTCTTCCTCCTCTGAGTGCCCTGTCTCTATCT +CTGGTCACCAGTGCAGTGGGGCACACCCCGTGGGGATTTGCAGGCCCTCAATGATAAAAA +CAGATTTGGTGCTGCAGGCAAATGATACTTAATACCCATATGAAAATGAGGTTAAAAAGC +AAAAACAACCTCCCAACCGCCTCACACCAATCAGGGTGGCCACTACCAAAAAAAAAGCAA +AAAACAAACAAACAAAAATGGAATACAAGTGTTGGTGAGGATGTGGAGAAGCTGGAACTC +TTGCACTTTGCTGTGGGAATGCAATACAGTGTAGCCACTGTGGGAATCATGACGGTCCCT +TAAAACTTTAGAATAACCATGTGTTCCTGAGATTCCACTCTGGGTATGTACACAAAGAAG +TCTCAAAGAGACGTGTACACTCATATTCACGACAGCACTATTCACAAGGGCCAGAAATCT +CTTCTGCAGCCAGTCATGTCCTCAAAGTGACCCCACCTTTATAAGGACAACCTGAAGGGG +ACCTCTGTTACCATAGTGAGAACACAAGAGCGTCTTCGGGTGTGCACAATGGTTGGGAAC +GTGGCAGAACTGGCTCTAGGACTTGCCAAGTGCTGCTGGTGCATCCTGGGCACAGGGCAA +AAGCCAGCTCTTCACAGGGACTTCTCACCTCACTGTCTATAGCAGGCTGGAGCACGGATG +TATGCATGCCCCTGCTATAGAGGCATGGATGTAGCAGTGACCCCCTGAGGCTGCCACGAG +TCCCCCATGAGTGCAACTGCAGAGACAGCAGCCGGCAGCAGACGGACTGAGGGTGGGGCC +ACCAGGGGACTTGCTCACTTCCAGGGGGGCCAGGCGGTCGGTGGGCCACTGCAGCATGGT +CAGCACTGACGGAGTCCTTGATAGTGGGGAGGGGTCTCCAATCGGCAGGGAGGGCTCTCC +AATCAGCAGAGAGGGGCTCCCATGACCTCTGTCCAACCAGCAGCCACTGCAGACTGTAAA +GACAGCTGGTGCCACATGCTACGGCCTTCTGAGCCCACGGTATGTGTCCTAGAGAGGGAC +TGTGCACAGGCACAGTAGGTCAGATGCATCCAACTCTTGGCATTTCGCTTAACCCCCTCT +GGGAGGGACCTCCCACCCCTGCATGTAGCCGAGCATGGGCTTCTGATAGAAGCAATCAGG +TTCTGCCCAAGTACAGGGTGGATACCACCCAGGGCAGAAGTCCAGAGGGTCACAGGGTCC +GGGGGCAACAGGGAGACACAAAGCCCTCTGCTGTCCCATTACACACAAGAGCATGGCCCT +AGGTGCAGATTGTCCCGGGGCTCAGACAGTATCTCTCAAAGCCTCTGGATGCTGGTACCA +GCATACCCCAGTAGCTCCGCACTAAGTGTGGGTCACACTGGGCAGCTCCAGCCAGAGCGC +CACCACTCCCCTCTGGACTGGGTGACATGGATGCTATGATGAGCTGCAGAAGCCCCCATG +CAGACGTGGGCAGGAATCTGTGCATGACTCACACATAGCACTTGGCATGCACGGACTGCC +CCGCTCTGGGGAGAGATGCTGTGACACATGGAGCACACCAGGAATGCCAAGTGACGTGGA +CCACGCATACCACATTGTCTCCAGCTGTTCATGTTTTAAGACCAGCCAGACCTCAGCCCC +GGAGCAGCAGTAATGTGCGACAAGGTCTACCCAGTCACCCGCTGCCAGCCAGGTGAGGCC +CATCCACCTGTCTCCACGATGCATGCTGCCCCCATCCAGCACGCGTGTAGGTAGAGGAGG +GAGGGGTCTCGGTCTAGGAGCCAGCCAGGACCCTAGAAACCTCTAGAAGGGAAGACAGAA 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+GCCTCAGCCCACTGCCCCCCACCACCACTTCAGTGCTCCCTGGACACCCAAGACTTGCTC +CTATCTGTCTCAGGGCCTTTGCTCCTTTGTTCCCCATGCATACGGTGCTCCTCCCCAGGC +ACAGGCATGGCGCCAGCCTTGGCTCCATCAATCAGCCCAGCTCCCCTTGTAGAACCCGTC +TCATCTCCTTCTCTGCTTTATGTATTTATTTATTTGTATTTTATTTTTATGTATTTATTT +GCATAGGGTCTTGCTCTGTCACCCACGCTGGGGTACAAGCTCACTGCAGCCTTGAATACC +TGGCCTTAAGTCACACTCCCACCTCAGCCTCCTGAGCAGCTGGGACTACAGGTGCATTTC +ACCATGCCTGGCTGATTTTCTATATTTTTATAGAGATGAGGGTCTCACTATGTTGCCCAG +GCTGGTCTCAAACTCCTGGCCTCAAGTGATCCTCCCATCTCGGCCTATCAAAGTGCTGGG +ATTTACAAGAGTAAGCCATTGCCCCTGGCATCTTTTTCCGCTTTATTTCTCCCCCTTGTA +ACTCCAGTCATACCTGACCTATTGATCTCCTTTGGGGTCTGTCTACCCCAACAGTAAATA +CTATTTCCTCTGCTGATGCCCCACTGCCCAGGCATAAGGGACCCAGGGCAGGAGCTCAGT +GAACTGTGCATGACAGGCCATGGAGGACCCACCCTCCCCTGGGCGATGTGGGATAGAGAC +AGGGAGGCAAGGTATGCCTACCCAGACCAGCCGGGCTGCCCCAGCACCAGGAACAGGCTG +CCGTGGGGGCCACAGCCCGCCTACACTCTGAGGAACAGCGATCCACACAACGGCAGCAGA +GAAGGCGTAAAACCACGAGGCCTCTGCACATAGATGAGAATGTGTCAGACGCACCCAGAA +AGCTATTCAATGAAAGGGCTTGTTTCACGGGCTTCACTGGCGGGCATGACAGCATTGCCC +ACATGTTCACTCTCTGCAAAGAAAAATGGGCCATTTTGAGGGATATAAATAGCCCGGCCA +GATGTGGAAGTGCCTGAGGGGCTTTTCCCAGGACTCCAGCGTGTGTCCTGCAGCTGCATA +GATAGCAGCCCCTCAGTGGGACCCCAGGGGTGGCCAAAGCAAGTGAAGGTCAGGGCCTGA +AAGGGTTACGTGGGGACCCTCCTCCCACGGGAAGGCAGGATGGGGCTCATCACAAACCAT +CACTGACCTGCAGGCTGAGCACGCCCATTGATGCATTCAGGGTACAGCTGGGACATGGAA +AATCAGTGGCAAATACACTGTGTAAGTCTTACCCACAGAAAACAAGGGAGACACAAGCCC +GGATAGCACGGGGCCTTTTGGGGAGGGGTATGCTCACTGAAAGCACAGGCCCGGGAGCCC +GGCAGATGTACAATCTCAGTGGTGAAACCTGGCTATTTGCTAAGGCCCAGCAGGCTATTT +TGTAATTGTCTGCAAAAATGCAAAATAATAGCACTTAAAGCTGGCTAAAAACACTCTCAA +AGCCTGATACGGTTGTTACAAGTCACTAGCTCCCAACTACAGAGGCGGGGCCTGAGCAGG +AGAGGAAGTCAAATCCAAGGGCACCAAAGAGCAGTTTAGATCCTACACCTACCAGGCGAG +CCACAGGTATAATTTCAGATGCTCTTAGAAGTCACGCTAAAAGACTAAGTTCGCGGCTTT +CGCTGGCCCTCTCCTCGAGGATCGAGGGAGCTCTGACCACAGCCTGTGGCTGGGAAGGGA +GGCAGAGGGGCGGCTCAGGGGAAACGAGGCTGCAGTGGTGGTGGCAGGAAGATGTCAGGC +AAAGACGAGCAGCAGGAGCAAACTATCGCCGAGGACCTGGTCGTGACCAACTATAAGATG +GGGGGGTGACATTGCCAATGGGGTACTTCGGTCCTTGGTGGACGCATCTAGCTCAGGTGT +GTCAGTACTGAGCCTGTGTGAGAAAGGTGATGCCGTGATTATGCAAGAAACAGGGAAAAT +CTTCAAGAAAGAAAAAGAGATGAAGAAACGTATTGCTTTTCCCACCAGCATTTTGGTAAA +TAACTGTGTATGTCACTTCTCCCCTTTGAAGAGAGACCAGGATTATATTCTCAAGGAAGG +TGACTTGGTAAAAATTGACCTTGGGGTCCATGTGAATGGCTTCATCACTAATGTAGCTCG +TACTTTTCTGACTGATGTAGCTCAGGGGACCCAAGTAACAGGGAGGAAAGCAGATGTTAT +TAAGGCAGCTCACCGTTGTGCTGAAGCTGCCCCATGCCTGGTCACACCTGGAAATCAGAA +CACACAAGTGACAGAAGCCTGGAACAAAGTTGCCCACTTATTTAACTGCATGCCAATAGA +AGGTATGCTGTCACACCAGCTGAAGCAGCATGTCATCGATGGAGAAAAAACCATTACCCA +GATTCCCACAGACAAGCAGAAGAAGGACCATGAAAAAGCTGAATTTGAGGTACATGAAGT +ATATGCTGTGGATGTTCTCATCAGCTCAGGAAAGGGCAAGACCAAGGATGCAGGAGAGAG +AACCACTATGTACAAATGAGACCCCTCCAAACAGTATGGACTGAAAATGAAAACTTGACA +TGCCTTCTTCAGTGACATGAAAAGGCGTTTTGATGCCATGCCATTTACTTCAAGAGCATG +TGAAGATGAGAAGAAGGCTTGGATGGGTGTGGTGGAGTGCGCCAAACATGAAATGCTGCA +ACCATTTAATGTTCTCTATGAGAAGGAGGGTGAATTTGTTGCCCAGTTTAAATTTACAGT +TCTGCTCCTGCCCAATGGCCCCATGCAGATAACCAGTGGTCCCTTCCAGCCTGACCTCTA +TAAGTCTGAGATGAAGGTCCAGGATGCAGAGCTAAAGACCCTCCTCCAGAGTTCTGCAAG +TCGAAAAACCCAGGAAAAAAAAAAAAAAAAAAAAAAAAAAAGGCCTCCAAGACTGCAGAG +AATGCCACCAGTGGGGAAACATTAGAAGAAAATGAAGCTGGGGACCAAGGTGGGTCCCAT +CTCCCCAGCTTGCTGCTCCTGCCTCATCCCCTTCCCACCACACCCTAGACTCTGTGAAGT +GCAGTTCTTCTCCACCTAGGACTGCCAGCAGAGTGGGGGTGTCCCTGCCGCCACCCCAGT +TTTGCAACCCACTCCCTTCCAACAACAACCAGCTCCATCTGACTCTGGTCTTGGGAGGCG +AGGCTTCCCAACCACAGAAGACTTTAATTGAACAAAAGAAATTAAATAATAAAATCAGGA +GTCAAAATTCATTGTCTTCAAGCCCCTCTTCCTAGCCTTTTCTTCTACTCTCTGCTTGGT +CAAGGTTTGTAACCCTACGATAGAACAGGGCTAAATTAGCCACCACCACTGAAAACTCAG +CCGAATTTTTTTATACCATTCTGATGTTAGCATTTTTCCATCTATTTGGGGGCTTTTTCT +TCTTTTTCCATTCTCCCCAAGTATTTTATCTGGCTTCAAAATTAGGAGGATTATTTTTCA +GATAGTTTTTATTCGGTGTGGCCGACTCCTCATCTGATTCAGGCTGTCAGTCAGGCCCCT +CCCATTTTAGGAGCTGGAGCCTTCACTTATGAAGCAATTCCCATCTATGAAATGGATCCT +CATTTGTCAATCTTTTTTCTTCCATTTTCACAAAGCTATAAAGAAATAATCCATCTCAAC +CTTACCCTTTTCTCTGGAGTCAATGGGGTCTTCCCTCACTCCATCTTACACAAACCTGAG +CTGGAAGCTCAACTGGATTTGTTCCCTGTTTGAAATATTGTGATCTCCCTCCCTTGAAAG +AAAAACGAAGAACCAGAGGAGTAGACTGACTGAAGATAAAACTCCTGGCTTTCTGAAGCT +ATGGATTTGGATTGGATTGCTGGGACTTTGTAGAGAAAGGTGACAAATTTCAGTACCTCC +GGCATGCTGTCCCAGGAAACTAGGGCTCCCACTAACTTATGAGGTTTTTAAACACATTGA +AAATGAAATGACATTAAAATAAATTTGGATTTGCTCATTTAAAAAAAAAAGACTAAGTTT +GCTTTAGTAATATATTTTATCTAACCCAATACACATCCAAAATACAATCCTTCTGCATGT +CATGCACGCAGGTCATGAACAAGGTAGTGCATCTTGCCTTCTGTGGGCAAACTCTTTGTA +ACTGCTCAAGGCATCTCGGCTCTGATCAGCACACTTCTGGTGCTCTGTATCAGGTGTGGT +GTCCAGCTAGGATACTAAGCAGGGATCCTATGAGGCATAAGGAGGCAGTACCACCGACAC +AGCCACTGATAGGAGGAGGTGCTATGGATCTGAGTGTGTTGAGGGTGTGGAAGCTTCTGG +TTACTATAAATGAACCCTTGGCCACCGGCCCCTCCTGTGTGCCAGAGGCAGCTGGATGGT +GCTAGTACCCTCTATGTCCTGTCTTGGTTTTTTTTGTTTTTTTTTTTTTTGAGATGGAGT +CTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGCGCAATCTCGGCTCACTGCAAGCTCTGC +CTCCCAGGTTCACGCCATTCTCCTGCCTCAGCCTCCCAAGCAGCTGGGACTATAGGCGCC +CACCACAATGCCCGGCTAATTTTTTGTATTTTTAGTAGAGACGAGGTTTCACCGTGTTAG +CCAGGATGGTCTCAATCTCCTGACCTCGTGATCCGCCAGCCCCGGCCTCCCAAAGTGCTG +GGATTACAGGTGTGAGCCACCGCACCCAGCCTTTTCACTCTGTCGCCTAGGCTGGAGTGC +AATGGTGCGATCTCAGCTCACTGCAACCTCCGCCTCCTGGCTTCAAGCGATTCTCCTATC +TCAGCCTCCAGAGTGGCTGGGATTACAGGCATGAGCCACCACGCCCGGCTAATTTTTGTA +TTTTGAGTAGAGATGGGGGTTTCACCAATTTGGCCACATTGGTCTTGAACTCCCCACCTC +AGATGATCTACCCACCTCGGCCTCCCAAAGTGCTGGGATTATATGCGTGAGCCACCACGC +CAGGTGTCCCGTCCTGTTAAAGCAGCTTTGGGATGCACGGCTTGACCATGCTTCCTCTGA +AGTGACCTGCTGCACTGTCTCTAGACTGCATGGCTTATCTCCAAAGCCAGGCTTCAGAGA +GGAAAGCTCACATTGTTCATCATTAGTCAGAGTAATGCACAGGACCCTGAGTGCCCATCA +GGGATGGGATCTTGGGTGTTTTCCAGGTAACAGCCTCACAGGGCTGCAGCAGAGGACCTG +GGACACCCTCCTGGGCCTCCTGAAACATGCAGAAGTAATTACCTCCCCTTTCAGTGTCAT +TTAATTAAATCTACAGTCTTCCTGCTCTCAACTCTGTGAGACGTGGAACTGTATCTGCTA +AAAATAAAGCCCAGCTCCTATGAACAGGGCTCCATCCCAGTGCAGGTGAAGCAGCCCTGC +CTCCAAGCAGTGGGGCACACTCAGACCCTAGGGAGGCTGGGCAGCACCCACACAGTGCAC +TTTATAAAGACTACAGGGTTGTTGTAAATTAAGAAGGAAGAGCTTAAATGCAGGCGGTAT +CAAAACAACCACCAAACTCAAAGGAATTCACTTTCTGCACTCAACTCCCCATAAGCACAT +GCAAGTGTAAGAGTTTGGGTCTAAGAAATCACACGCAAGACACAGCATTGTATCCTGTGG +CTCTCTGGCTCCCCCAGACAGATGTCCAAGCCAACCTGTGCTCCTTTCTCTGAGGACGCA +GAGCCCTTTGCTGCCTGTCTTATCCTATGCTTCTAGGGGAAGCTGCTGGAAGGCGATGGC +CCCCAGGCCGTGTTTCCAGCCACGTCCAACAGGCCTGCAGTAGAGACCCCAGTACCCCAG +ACCAATCTAAGCCAGGCCTCCCAGAACCATCTGGTCGCGGCCCTCGCTGGGTGGACACAC +AGCCCTGACGGTCAGGTTCCTGTGGTGGCCGTGCTGTCTCCAGGACTCAGCATCACAGGG +CCTGGCCCACAGTGGCACCGGGAACCACAATGCCTGCTTTGTCCCCACACAAAGGCTGGC +AAAGCACCTTATATGGGCCACTTCACGCTGGGAAAAGTCCCTTAAAAGTTATTTTTGCTT +CTACTTCAACCCAAGTTGTAGAATATATGTCTTTTTTTTTTTTTTTTTTGAGATGGAGTC +TTGCTCTGTCGCCCAGGCTGGAGTGCAGTGGCGCGATCTTGGCTCACTGCAAGCTCAGCC +TCCCGGGTTCACGCCATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGACTACAGGCGCCC +GCCACCACGCCTGGCTAATTTTTTGTATTTTTAGTAGAGACAGGGTTTCACCACGTTAGC +CAGGATGGTCTCGATAGAATATATGACTTAATCTTCAGTATGTCCTTTGCAAATGGTCTT +GTGTATGCAGACTATCTATGATGTGAAAGCTGCATCCAGGAAGATCCCAGCCTGGGCAAG +ACCAGGAGGGCCAAGGCACCCCTGAGGCAGTAGGAGTCACAACCCGGCTTTCTAAAGGGG +ATGCAAGGACTTACATATCCTGCCTCTTACAGCTAAAGTCACATCTTGAAACGCCTTCTA +ACACAGACACACCTGCATCAACCTTTAATCCATGTCTCCAGGAGTGGCCACAGAAGGTGG +TGTGGACGTGGCTGAGGCTCCCCTAGCTTGGTGTGGCTGACATGGTCAGCCCCCCCCAGA +TTTTCACTCCCTCCTCTATTTCCACACCAGATCTAGCAGGAGTGGACCTTGGGGGCCTTG +GACAGGTGGGCCCTCCACCAAATCAAACAGAGCAGCTTCTTCTGATGACCTCTTCTCTTC +TGGTTCCATCCAAGCACGTAAACAAGCCGGAAACGAGAGACCTGCATAGGTGGCTGCTGG +CCGAAGACGGTCCCTCCTGGGGCTACCGAGGGCACTTCCCACACCCAGTGAGAGTGTCAA +ACCGCAGTGGGTGTCCCACGGTGACGGCAGGGTGTGAGGGCAGCATTCTGCACAGGGTGA +GTCCCCCAGAGCCTACAATCCTGCACAGCACAAGGACATGTCCCATGCCAGCCCAGGCCA +CCCTCGGGGTGGCGAAGAGACACAGCCATGCCACAGCACTCCCAGCCCCCAGCTGACCCA +GTGGGGCCCTGGCACAGGACTCTGCCCAGGCGTGTGCCTAGCACGGGTGAGGAAGCCCCG +CCCCTCGAGGAAGCTGCCCCGGGTGGCTCTGCCTCTTCACATTTACAGAGAAGGAAACTG +AACCCATGAAGTGACGGGCCAGCCCATGGCCCAGCAGCCCTGCAGGGCAGGCAGCCCGAT +CCCAACAGTTGGGAGGGGGTGGGGACAGGGCCAGAGAAAACGGGTAGCCTGGGTCATAGC +CTACAACAATATCACTTCATCACGCTGTGCCTCCATGGCCTCATCCATGACAGGGAGGGC +CCAGTGCCCTTTGGGGCTGCCATGACATGCGGACTCGCACCCACATGCTGTCTGTGACAG +GGCCCGTGTGGCCTGATGCTCTGAAATTTCAGACAACAAGCAGCCCCTTCGTCCACTCTG +CACACTTGAAAGGCAGGGGTGGGAGCAAAGGTGTGGCAGCCCAGGGGGCTGTCCCCGGTC +CACCTCACCCCAGCCCAAGCCACTGCCTTTGCCAGACCTCCCTGAACACGGGGCATGGGG +GGTGTGAGTTAGTGGACAGAAGAGAAGCAACTGCCCACCAGATCCCGAAGACCCCTAGGG +TCGGGTGAAAGACCACCTTCAACAACCCAATATGAACTCCTAGGCGCACCAGTCCTCAGG +GGACAGTCCAGGCAGGGGCACCTCCTCAACTGGGGCCCTTCCCTTCCTGCCGGGGAAGCT +GGTGCTGAGGCTGGGTACTGGGCTCACCACCAAACAAGCCACACTCAGCATTGCCTCGCT +CATTGCCTCCCCTGCCCCACCCACTCTGACTTCCTCTATATCCACATCCCCTAAACCGAC +CCTTACCACTCCAGGCAGAACCACCTGAGCTTTCAGAGACAGGCCTTCCTCCCTCACTTT +CCAGACACCTGCCTGGCAGGTCACACAGTGAATGGGCATCGCTGCTGACTGAGGAATGGA +ACACCGGGACAAGACCTTCTGAAAAGCCAGTTCCAAAAGGAACCATGGCTCTCAGGCAGA +CGCCGAGACGCCGACACTTACCAAACCATCAGTGTCGTCAAACATTTCAGCACATGGTTT +CTTTCCACTATCTGGTGTTAGCAGAGTCTGAAACAGAGTTAGAAAAGGGCACATTTTAGC +AGGATAAACTACCAGATTCCCTTACAATATACATACACACAATTCCATACCCCAACCCTG +TGCGAAAAATGTCCCCCAGGGACTGCAAGAGCATCGTCCTAGAGAACTGTCAGTTACAGG +ATACAGCTTACCTGGCCACGTGAGACCAGAGGAGGCATCACAGCTAACAGACAAGGATTA +TCAAGAACTGGGAGGGAGGCATCATCTGCACCTTCCTTCACCCTACCCATCTCTCTCCTC +CCCTCTGCTCCTGGCCAGGCACCAACTTAGCAGAGAGCCTCTCCTTGGCTCAGCACACAA +TCACTAGGCGTGAGCTCTAGTGCAGGAGGCAGCCAGGGTGGGCCAAGGCCTAACCCAGAA +ACCCTGTGACCCACAATGAAGGTGTAGTCAAGAAGGACACTGTAGTACAAAGCTCCAAAA +CAGTCCCTAATTTAAAATCACATATGAAGACAATGTCAGTGCTAGCATTCAATATTCCAA +CACTTTTTAAGTTTTAAAATTAATTACATACTCAAAAACCAAAATCAGGAGAAGAAGGGG +AGGAGAAGGAGGGCAAGGAAGAGAGAGAGAAGAAAAGAAGAATCCAAACAGGAACCAGAA +TTTGGGAGAGTTTTTCTTTTTGAGACAGTCTGTCTCCAGGCTGGAGCGCAGCGGCACGAT +CTCAGCTCACTGTAACCTCCACCTCCCAGGTTCAAGCAATTCTGCTGCCGCTGCCTCAGC +CTCCTGAGTAGCTGAGCTTAAAGGCACATGCCACCACACCCGGCTGATTTTTGTATCTTT +TTTAGTAGAGACGGGGTTTCACCATGTTAACCAGGCTGGTCTTGAACTCCTGACCTAAAG +TGATCTGCCCGCCTTGGCCCTAAGTGCTGGGATTACAGGCATGAGCCACCGCGTCCAGCT +GGGAGGGATTTTTTTAAATAATGTCAGAAGTAGCGGAAGGCTTACTAATGCCCCTGCATT +AAGGAGAAACATGAATCAACACTCTGAGAAAATGCAAAGGGCTCCTTCCTTCCTCACTGG +CCTCCTGGAGCAGGGAGTGAGCATCGCAAAGTCCCCTCCCACAAGGCACAGAGCCGCAAA +TGGCAACTGAAGGGAAAAGCTGTTCGATGTCATTAACGATGAAAGAAACAAACTGAAGCA +GGATGGTCGCTTTCATCTTTCTGATGAGCAGTAACCTACAAAGCTGAGCAACCAGAGCCT +GTGATGGGGTGGAGCAACCAGAGCCTGTGATGGGGTGGGGAAACCAGCGCCTGACAGGTG +GGGAGCAGACCCAGTGCACCTGACTGTGACGCTCGGGATGCTGCTGAATCACATTCCAAT +TGGACACAAAGCTACACCATGAGGGTGCTTCCTGCATCGTAGCAAAGCCATGGAAACCTT +CCAAGTCCATCAGTGGCTGACCAGAATCAAATAAATGGTCTATCCAAACACTGAAGTGTA +TGCACCCATCACAAAGAACAAGGAGGTCAGCTGGGCACAGTGGTTCACGCCTGTAATCCC +AGCACTTTGGGAGGCCGACATGGGAGGATCGCTTGGGCCCAGAAGTTCAAGACCAGCCTG +GACAACACAGTGAGACCCCATCTCTACAAAACAAAGTTAGCCAGGCATGGTGACACATGC +CTGTAGTCCCGGCTACTCGAGAAGCTGAGGTGGGAGGATTGCTTGAGCCCAGGTTGTCAA +GCAGTGAGCTATGACTGTGCCACTGCACTCCAGCCTGTGCATCAGAGTGAGGCCCTGTCT +CAAAAAAGCAAATAAACAAAAAACAGGCCAGGCACGGTGGCTCATGCCTGTAATCCCAGC +CCTTTGGGAGGCCGAAGGTGGGTGGATCACTAGTTAGGAGATCGAGACCATCCTAGCTAA +CACGGTGAAACCCCATCTCTACTAAAAATACAAAAAATTAGCCAGGCATGGTGGTACACG +CCTGTAGTCCCAGCTACTTGGGAGGCTGAGACAGGAGAATCACTAGAACCCAGGAGCCGG +AGGTTGCAGTGAGCCAAGATCGTGCCACTGCACTCCAGCCTGGTCGATAGAGCGAGACTG +GGTCTCAAACAAACAAACAACAAACAACAAAAAACAAACCCTGAGGAGGTGACCTTGTGT +GGAAAGGGAACTGCCCAAGACAGAATAAAAAGGCAGGCTGTGGAGGGGAGCCAGGGCAAG +CCCACCACTCCACGGTGGCCTTACGTATGCATGTGAGTGGCTGCGCAGGAAACACAGGCT +TTTGGGAGGACAGTCCAGAGAGTAGTAACAGGTTTTTCGTGCTGTGGAGTGGCCTGGGGA +TCCGAAGGCAACTTGGTCCCTGCATTTCTGAGCTTCCGTATTAGGGCTGTTTTTACCCTG +CACACTGCAACCGATACATACCACAGTTGCCCACATAGCACCGCCCCTTTTCTTTAGTGG +AAACTACAAATTCCACATGGTGCATACATCCTACGGAAGGCCAACCCATGGCTGGTCACA +CAGTTCCCTTCCTGGGCCCACCTAAAAGACTGCCTGCCACACACATGCCACACACATGCC +ACAAACATGCATCACATGCATGCATACATGCACACACCCATCCAAGCAGACACACACCCA +CCCACACTTACATGCACACACGTATACACCTATGCACACAGGTACACCACACCCACATAC +CCATGTAAGCACACATGTATATTCACATACAAAATCACACACAAACCTACAGAGACACAC +ATACATACACATGCACATATATACATCCAAACACGCACATCCATACACACTCATGCACAC +ACACACATATACATATATGCACATACAAACATGCATGCCATATTCACATACACACTTATA +CACCTAAACACACACTCATACACACACGGATACATATGCCCACATGGATACACATACACA +CAAACACATGCACAAACATATGTACCTATACGCACACTCATATACAGATATACTGCACAC +ACCCACATGTACTCATATACACATCTACCTACACACATGTGCCTACACACATATGCATAC +TCATACACACACTGTGCATGGTCCTTATCCTCTCCCCAAGGGAGCTGCAGCCCAGCATTC +CCACCCACTCACACGCTGGGGAAAGAATCACCTCCTTCCTCCTCAGCAGCTCAGAGGCAG +GTTCTGAGCCATCGCAGCCTCCTAGAGACCCCATGTGCCTGTGGTCAGTGGTTCTCATAC +TGCGGCCTGCAGCAGAACCCCTGGCAAGGATCTGAATGCCAGATCTCTGGGCCCCAGTTG +GAGCCCCAGTCCGGTAGTGCTCTGGGGGGGTCCAAGAACATGCATTTCTAATGGGCCCTC +AGGTGATGTTGCTGTAGTTCCAGTGAACAGCCTCTAGTCCCTGGGGCAGCTTAAGGGAGT +CAGGGTTTGGATGTGGCTCATTCATTCCGTCAGTGAATGCTTTTTGCTTCTTTTGTGTGC +CAAGCTGCATCAAAAGTCCCTGGCTCTCCTGAGGACGCAAAGAAACAACTGGAGAAAGTC +ATTTCAGGGAGTGAGATACTGATAAGGCAAGAGCATGTCAATGTGAGAAACAGCCTACAA +GGGTGTTGGGGGGGAGTCTTATTAACATTCCTGAGGGTCTTATCCTCCTGGAGAGATGAG +AATCCCCCTGCAGACCCAGAGCCTCTTCCCTGCAGCTGTCCCTGCTCAGCCCTGGGTCCC +AAAGGGGGCTGACCCTCATCCTCCCTGCAAGCCTTGGGGGCTGCCCCTGTGTGTGGCAGG +CACCTTCCTTCCTGTCTCCACCTGGCTCAAATGCCACCTACCTAGAAGCAGGGACCAAGG +TCCTCAGCTGGTCAGAAAGGCCCACACGCCACAAGACCCAGGCTAAGATTTGAGGGCCCA +TGTGGCTAACACGAGGGAGCCCAGGCCAGCATTCAGTTACTAAATAACACACCCTATTCT +GTGTAAAACTCTGGGTGACAACTGCAACAATGTCAAGTGCTCCTAGAAAACAGCAGGAGG +TAAGAAATCCCCTGCCCTCTGCGTTCCAGAAACAACTGCTACAAAAAAAGCCCCTTCCCC +ACAGGACTGAGCTAAGGCTCACGATGCCCCCACCCACCCAGGATAAGGCCAGACACAGAA +ACCCACCAACGCCTGCTCTGTGCCTCTTGATGGCCAGTGGCACGATGCATCCCCCGCCTG +CTCCCGATCACTCACAACAAAATGCTCATAACCAAACCTTGCTTCGCTTCTGTCCTTCTC +CAGGCCCCTTGGGTCCCACAGAGCCAGTGCAGCCCCTCCTGAGAAACAGCTGGCCTTGGG +TAAGGCATCCTTTGACCCTGCCACCTTCATCCCATATCCCACCTCTGGTTCTTCGAAGCC +TCATCTACACCACCCTACAAAGAAAAGCCCTTTGGCCTAACCTTTCAGACACATGTGATC +TCATGGTCAGCATGTGGCCAGGCCCTGGCCCCTACTGTGACAGTCCATTCCTTCCTTTGC +ATACTCCTAAGAAAGCCTCTTCTTACTAAGTCTGGATTTGTTTTATATTTGACAACTGCT +TACTGATTACAAACAACTTGAAACTCCAAAATGTGTCACACACTCATGCAATGGATGCAC +AGGTGAGAGCTTTGATTTCTGCCTCCTGGAAGACCGGTACTCACATGTTTAACCGAGGTT +CCACCGGTTCAGACCCACTGCTCATGAGACGGCTCAAGAATATGTCAGAGATACCCCAGC +CTCACATGCACAGCTGGTCCTGGAGGCCGCAGAGCAAGGAAAAAGGGGAGAAGCAACACT +GAAGGTGAACCACACCCCTCACAGACACGGGCATCCTACAGGCCCAGGAGAACCCATGCC +CTCCAGCGTGGAACTCAGCACACTGGGCATTTTGTGTAAGCTGCCCTCCTCCTGCAGACA +GGCAGGGCTTAGCAGGGCCAGCTGAAAATGACACCTAGCCTCATATGTGGCCACCACATA +TGCCGAAGGGGAGGACGGAGAAGGCGACCTGCTGTTCCCCACACCCCGCAGCAGAGAGAA +AGGGCTCCCAGGGCAGACAACCCTATCACCTAATCCTACAGTCATGCTCGGGGGCTCTGC +TGGGCCCCTCAGCACACTCATGAAGCCCCAAGGTCTCTTTTCTAAGATCACTGCAAACTG +CAACTGAACACACGAAAGAAAATGTGCATCTCACTGGAGGTCAGAAAAATGCAGATTAAA +GCAAGATGCCACTCTCCCCCTACAAAATGACCAGAAAAAATAATTACAAGGCTTAAGGTG +GTGTGGAAGTGTGAGCCCCTCCCTGCTGTCAATGACTTTTCTAGCAAGCAGCATGCCAGG +GATATCAGGAACCTTACAAGGGTACCTCTTAGCTATCAGCAACGAGCAGAAATTGGGACC +GGTAATCCCAACAAAACGTTTCACCCCATATACTCTTGACTGTGAAACTGAAAAGCGCCC +CCACAGAGAGAAGCACGTCAATAGATAAAGCAGCACTCGGGCTCCAAATTGTATGTTTGC +GTCTTTCACATGGATGGCTATGAGCAAATGGCTGCAGTTCTGAGTCCTGACAACTGAGGA +GGCAACGGTGACTCACTGCCCTCCCAGGACAAGTGTGGGCACCACAGGAAGGCTGCCAGA +ATAAACCTCCAAACATTTTTCTCCTATACTAGGAGAGTAGCATATGAACAGAAATCATGG +TGTCCTGGACATCATAAACCCCCAGAGTCCTGGGAAGCCTGAATCCTAGGGCCAATGTGT +ATTTCTTTTTTCTCTTTTTTTTTTTTTTTTTTTGGAGACAGAGTCTCGCTCTCCCTCCCA +GGCTGGAGTGCAGTGGTGCGATCTCGGCTCACTGGAACCTCCACCTCCCGGGTTCAAGTG +ATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGCGTGCGCCACTACGCCCGGC +TAATTTTTGTATTTTTAGTAGAGACAGGGTTTCACCATGTTGGTCAGGCTGGTCTCGAAC +TCCTGACCTCATGATCTGCCCACCTCGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGA +CACTGTGCCTGGCCTGATGTATATTTCTTGAACAACAAATGGGTAATTTTAAGGCTAGGA +TGAGTTTTACCAACCTGCTTTTCCTAGTGATGCATTAAACGTGGTTTGGGTTAAGAAGGG +AAATTCTCAGGCTTTGCTGAATCCCTAACTGAAGCACGTGAAGCTAAAATCACTCCCTCT +CTGCCCAGGGTGGTCTGCACACCCAGAAAGAAATGCCAGAAATCGCTTGGTGTGAGTGCA +CTGCAAATTCTTGAAACTTGATTTCTCACAGGTATAGATCATCTGGCTAACTCAGTCCAG +AATTTAAATACGGTGCTATTATAATTCACAGTAACTAAGATTATTATCTGTACATTAACG +TATGGCACAAAAGCCCATAAGGCTAGCTTCTACAGAGAAGCAGGCTCCAAGGGAAGTGGC +CACCAATGCTCTTCCTTTATAACAACATTGATGTGAGCAACGGCAGGCAACCGGCTGATA +AAATGTGGAAATGTTTTTCCCTGTGGCATACCCACTTAAGGAGAGCTGTGTTTTCTGTAC +AAAATAGGTGGGGTTGTTTTTGGCAAAATGATGGAATGTTTTCAATTTGAAGGAGTAAAA +ATTCCCCAATACCAGTCTACGGCAAACAACTCAAAACAACAACAAGCCAACAACACCTCC +TATTTAAAGCTGTCCCAGCCAGATGCAGGGGCTCGTGCCTGTAATCCCAGTACTTTAGGA +GGCCAAGGCGGAAGGATCACTTGAAGCCAGGAGTTCAAGACCAGCCAAGGCAACAAAGTG +AGAGCCTGTCTCTACAAATAAAAAACAATTAGCTGGGTGTGGTGACATGCACCTGTAGTC +CCAGCTACTTGGGAGGGTGAGGCAGGAGGATCACATGAGCCTGGGAGTTTGAGGCTGCAG +AGAGCTGTGATCATGTCACTGCACTCCAGCTGGGAAAAAGAGCAAGACTGTGCTGGAAAG +AAAGGAGGGGGGAGCGAGCGAGGGGAGGGGAGCGAGGGAGAAAGAGAGGCATGTAAGAGA +ACACAGAAAAGGGAAACAGAACAAAAGGGTCTGTACTCTGAACACTAGAATGTTCCTTTC +TACTCCTTAAGCCAAACCTAGAAGGCTTCTGGCACTCTCTTCTCTGCATCCCAGTACCCA +CTTCCAGGTTTCCAATGTGTTGAGTTCAGACTGGGGAATACCAGATGGGGAAAAATGGTA +GACTCATGCCCAGTTGAGGAATACTTGCAATTCTAATCTTCCTCTCCAAACCACCTGCTA +CTATATTCTTTTCAGAATCTTTGAATAGCTGCTCCCTGCATTTGCAGTGGGAAAGCCACA +GTGGAACATGGTTAACCCAGCTTATTAACCAAGCCCATTCATTTCTGAGCTAAAAATCTA +CCTGAGGCTCACACCAGCCATCTTTTGCATGATCCATCTGGTCCTCTTCGTAGACAGGGG +TCCATTCCCAGGTGCTAAATCTGTTCAGCAGGGCTACTTGGGGGCTTTTCATGATCAAGT +CCCAGACTTGCTCTTTCTCATCCAGGTCATGACCAGCCCTTTTTCGCTGCTGCTTTTTCA +TTTTCGCAGCAGAGGTGGGGAGGTACAAAACTAATTAGCGTCAACCAGTCTCCAAAGTGT +ATTCACAACACAAGGTCTCTATGTTGTGTTTAAAGAACCAAATGGTGGGCCGGGCATGGT +GGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGCGGGCATATCACGAGGTCAGG +AGTTCAAGATCAGCCTGGCCAACATGGTGAAACCCCATCTCTACTAAAAATATAAAAATT +AGCAGGGTGTGGCGGCGGGCACCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGGAGGC +TTGCTTGAACCCAGGAGGTGGAGGTTGCGGTGAGCCGAGATTGCACCACTGCACTCCAGC +CTGGGTGACAGAGCAAGACTCCGTCTCAGACAAAAAAAAAAAAAGAACCAAATCGTGCCA +ACTAGAGCCAAAGGCTTAACTTCAACCCTTGCAGTCATGGGGGCACTTTCTCCACTTTCC +ACCTTAGACACGTGCTTTTGGGGTTCTATGTGCTTTTCTTAAATTTCAGAATCAGAACAC +CAGTCAAAAATGGAGAGTGTGACTCACCTTCCCCCACCCCCAAGAAAACTGCCACAAAAC +CGCACTGTGAGCCTGTTTCTTCCTCTCTTCTCTCAGATGCACTACGCTCTCAGGGACCAA +GGACACTTTGTTCTAATCATGTTGAAGATGTAAAACAAAAATACTTAATTGTAAATTGAA +TTATTTCACCAAGATGCTACCTGTGAGAAAAAAGGAATGGCTGGAAATCCTGCCTTCCGA +CCTGGGTTTCGGATGATTATAAACAGCTGGGGTGGGGCTGAGGACCTCAGGGGCAAGGCA +GCCACAGTTGGGGGTGGGGGGCAACACATTACAAGTCCAGCAGCAGGGCGCAGCCAGGCT +GCCTCTGGCCACCTCCCCAATGCCCAGGATCTGGACAGGAAAAGACAGGAGTTCATCAAT +AAGGAGAGACCCCTCAGATGTGGGGTGCAACACCCCAGCTAGGAAGGGCAGCAACAGGTC +CTCTCCCTGCAAGATCATGGGAACAAAGAAGAGGACAGGGACACTGAGGACAGGGTTCAA +AACCCACTGGTCTCCCCAGAGTGAAGCACCCCCAGGGGAAACTGACAGCAACTCAGGCAG +TCACAGAGGTCAACCATCAGAGAGGTGAGTGCTAGACAAAAACCACATCCTCATTCTTTG +GGTCCATTAGGAAATGGGCAGGGTTGCAGGGGTCCCCCGCCTCCTGGAGAGGGCTGGATA +AGCCTGAGTTACCACGGGGTGTGGGGGGAGGGTGCGGAGAGCACCCCCAGGGCGAGGGTC +CTGCTCTCTGCTCAGCCCACAGTGACATCTCTAATGCAAGCATATGCTGGCTCTAAATTA +TATTAGCTTGCTTGCTTTATTTGGATGCATCTCTGTTTTTGACACCATGTCCTCTCTATA +GCTATAAACATCTCGCATGCTTTACAAAGCACTGAGCACACAATAATTAACCAATACTCA +CTGACCAACCTGTCAGGGGCAAAGAGGACCAGCCCAGGAAGGGGGCACATTTCCACATAT +CACCCAAGAGCCTCTCACGCTGGCTCAGACCCACAGACAAGACTGGGAAGATCCGCCCAC +AGAATGTTCCTCCTTGCCCTCCATGACCAGATTCTCACTTTAAAAAGAGCCCTTAGTCCG +GTGCATCCCGCGGAGAACAGACAAGAGGGGCCTAAGTCCCCAGGAAACCAGCACCATCCA +TCCGGTGAGATTGCTGGCCACTCAGCCCAGGGGTGATGGCTGCTAACGGGTCACTTAAAA +AAAATGACCATGCATTAAAAACATTATTAAATCATCACTCACAAGAGAACCAAGGAGGTG +TCACAATCCCTTCAGAGGGGAAGTCAAAGAATCACAAAAAGACATGGAGTTGGCTGGGGG +AATGGGGATGGATTGGGCCATGATGGATTGATAATTAGGGGGCTTCCTTTTGGGGTGCTG +GAAATGTCTTGGAGCTAGAGGTTGCACAACATTGCAAATGTACTAACTGCCATGGAACTA +TTCACTTTAATATGATTAACTTTATGTTATGTGAATTTCACCTCAAGAAAAAAATAATAC +AGAGTAAAAGAATATTGACATGAATTTCCAACGGACACAATACCAGCCTTTTCCATGGGG +AGTCAATTGTCTCTCCAGGAGGCTGAACCCATTTGCACGTCTAGGGACAAGGATTATTTG +CATTGCCTTCGGATATCTATGACTTACAGAGCTGTACAAAGACAGGTGAGCCCTGGGTGG +CCCCAGTGCTCCATTCAAAGGCTGCCTATGCCCAAGTCCAAGGTGGAATGAGGAGAAGAT +GGAGTCCACAGGTTTAGGAGGAAACCAGCTTTAGCCGATGGGAAGGTGATGCTGCAGAAT +AAGGTGTGTCTAGAGATGGTGTCAGGAGTGACTCCTGCATTTCTTGGAGGCAGGGGGGAA +GGTGGGCTCACTGGAGCACTGGGGCTTGAGGAGATGGTCCACCATGTGACACAGTGAGAA +GCCGAGGTGTCCAAGGCACCATGAAGGGGCAGGACCACACAGGGTGCACGCCAGGCAGTT +TGCAGCCCTGGCCTGGCTAGGGGCTTCCGTAGCACAGTGCCGCAGCTCCTGGGGCACACA +CCAAGGGATCAGGCACACGAAATGCTCAATGACACACACAAACATAATTTCCCCTGACTT +GTACAAAAAATAGGGTGATCACTCCGCTCTGAGTTCCCACGTAGTGATGCAGACTCATTT +TCAGAAACGCCTTTTCTTTCTGCCAATCTGGAATTCTTTCTGGGCTCCTCGAACACCTCT +AAGAATCCACAACCTTAGACAGAGGGCTGCCTGGGGCCTTTCCCTTCCGGCTTTCCCCAG +GCATCCACACCTACAACACCTGGGACACGCTAACACTCACAGGCCAGGTGAACACATGCT +TGACTGCTCTCCATATGTACCGAGGGCTGCCCATGACCTCTGTGAGTGACCTTTCTGTCT +AGACCATACGCAGTGCATCATCGAGGGAGCACACAGCCCCCGTGTGCACAAGGTCATGCT +CCAGAAGCATCACTCACCTGCATGTGCACACTCTCAAGGCACAGCCAACTCCACTTTTCC +ACTGCAATTAGTACACAGTAATTATTACCCAAACCCAGCACATGGAAACATGGTCTGCAG +CCTACATGGACTGTGTTTCCAGTGAGTTGTCCTTGTGTGCAGCAGGGAGGCGGCTACCAG +GTCACAAGCATTCACCTCGGAGTGCACATGACGATGACCAATACGAGCCTGATGTCATTA +TCGGAGCCTCCTTCAAGGATGCTGCTCCCTCCCCACAGTGGTCTTGTTACTCTATAACTA +GAAGTTTCTGAGCCACCAGCTCCAGAATGCAAGGCCCAAAAAGGGCCCTGTTACTCTTTT +ACAAGCAACCAGAGCAGAAACGAAAATGTCACCAACCTCCCAGAAAGAAACTGAATTATT +CATCTGCAGCATTCACAGCCCCATGTGTGAAGTTAACGGGGGTTGTCCCCCTTGTTGTTC +AGGCTGAAAAGTTTCCATGACTAGATGTGGGCACTCCTGTCCCAGCTCGTGTATCATGCC +TGCCTCCTTCCTGGTGGCCACACAAGGACATGGGTACACGGCCCTTGCACTTGTATGAGC +ACGTGCCCACCCTTTCTCCTCACGTCCTCACATCCCCAGCTTCCCGGCTCCTTACACCGT +AGAACCTGGATGACCTTGTGAAAACACACACATCTGATGCTCCCTCCGAGGTCCCTATAC +CACAGCATCCTTTGAGTTCACAGCCATCCGGTTCCTACAATTCAGCCCCAAAGGAGACTA +GGGCCATCAGTTACATAAGGACATACATGGTGGAGGAGTTGATTTCATTCTCCTCCTTTG +AGTTACCTGAACTTCTTACAGGAAATGTGTTATTTGTTTAATCCGGGGGAGTGGGGGAGG +GGGAACCACACCTGGGAGCGCATGATTTTTTTTTTTTTTTTTTGAGACAGAATCTCACTC +TGTTGCCCAGGCTGGAGTGCAGTGGTACAATCTCAGCTTACTGCAACCTCTGCCTCTCAG +GTTCAAGAGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTGTAGGTGCGCACCATC +ACGCCCAGCTAATTTTTGTATTTTTAGTAGAGACAGGATTTCACCACGTTGGTCAGGCTG +GTCTTGAACTTCTGACCTTGTGATCCACCTGCCTCAGCCTCCCAAAGTGCTGGGATTACA +GACGTGAGCCACTGCACCCAGCCTCATGATTCTTATAAATTGCTGCAAGGATATGCCCAC +AGCAGAAGCAGGGAGAGCTGGCAGTGGCATGTCCCACAGCCTCAGGCTTGGAGAGCAGCC +CTCCCAGCCCCAAGGGCTCTCCCAGGGCTGGAGGTGCTTAGCCAGCTGTTTATGCATACG +TTACACAACCCTGCAGCAGAAAGAGAGTCAGCCTGTCCAAAGAGAATCATTTGCGAGAAG +ACACCGAAAGACTAGGGTAGTCGTGGTGTTAGGCCTGCTCATCCAAACGACTTTGATCAC +TGAGAAAACTCAGCGCCATAGGATGGCTCCAGGGATTGCACAGAACCCCACTCCACTCCA +CCTGCAACAGGTATTTCCAAACCCTCCACATTTGCAGAAATCTATTTTCTTTTTATTGCT +CATAAATCACTCTATTTTAAACCCCAGCATGACACAGATTTTTTAATTAAGTGAAGCAAA +ACTAATCTCACTTGAAGAATCACTACAAAACTGTGACCTTTTCCCTCACATAGGAAGATG +CTACAATATCAGGGTCAGGAACCAAATTCCCCAAAGTCCATCAATGAAAAAATGTCTACT +TTATGACCTAAGATGAAAGCTGACAACAGAGCGTTCAGAAGGACACACCGTCAACTGTCT +TCAGTCCCTGACTCACCAAATAAAAAGTGACGGCAAAGCAATCTCTGCTTAAACATCACT +CTAAAAACATACCACTCCTTTTGGCCTTATTTTTCTTGGGTTTTTCAAACAGGCTAATTT +GTGGCCTTTATTGGAAATAAACAAAACATAAATAAATCAGTACCTATCAACACGCCACTC +AGAATAATCACCTCAAACACCCTGGAAAAGTGGTGAAAATCTCATCCCCCCTCTAAGTGG +TGGCTGCGGGTTTCTTCTCACTCTGGTATAAGGCTGCCCAGATTCTCCCGGTGTGTAATG +CTTGTGTAATGCTCGGGGGCAGCAATCTGAAACTTCTAGAGACACTGAAGTCCTGCAGGT +CACTGGGGTAGCTCCTATTAACTTACCACTCAGGCACCAAAGGCTACCCCAGGGCTTAAA +AGCCTTAATGTCCCTCCTAAGGCACCTCATTTGCTGCTCCCCAAGGGGTACCATGTAATC +CAAGGGAATCCAGCCCCATAAGAATCTGGTAATACCTAGGACTACAGACTACAGTCCTGA +TTAGACTGGTTCCACACAGAGGCTGCATTTAAAACACTAGCCCTGAGGTCCTCATATGTT +AATACATTCCCAATTCCCAATATCAGGAAAGAAGGAAATGTTATCACTACAGACCCCATA +GACATTAAAAAGGAACATGGCAAACAACTCCGTGCACAAAGAGTCAACAACTTAGAGGAA +ATGATCAAATTTCTCAATAACAACCAACCACCAAAATTCACACAAGATGAAATAGATACC +TGAGCAATACTATAAACAGGAAAGAAATAGAATATGTAGTTAAATACCTTCTGAAAAAGA +CATCTGAAAAGGCTCAGAGATAGGTTCCTTACATGTTTGGTAGAATTTTCCAGTAAAACT +AACAATTACATACACTCTCTTCCAGAAAATAGAGGAGGAAAAAACATTTCCCAACTTAAA +TGAGGCTAGCACTACCCTGATAGCAAATCCAGAAAAAGACATTACAAGAAGACTATAGGA +CAATACCCCTCATGAACACAGATGCAAAAATCCTCAACCAAATATTAGCAAACTGAATCC +AGTAATATGTAAAAATAATGCACCACAGCCCAAGGGAGTTGATTCCAAAACACAAGATTG +ACTCAGTGTTCAAAAATCAATAAATGCAAGCCACCTACTCACAGAAGAAAAAGCACACAG +GCATATCAATTTATACAGAAAATGCATTTAAAAAATTCAACATCCATTCATGATAAAAGC +TTTCAGCAAACTAAACCTAGAAGGGAACTCTCTCAGCCTGACAAAGGGCATCTATGGAAA +ACTCACAGCTAACATCATATTTCATGGTGGCAGACAGATGCTTTCACCGAAAGTCGGAAG +CAAGGCAAGGATGTGCTCTCACTACTTCTCAACATTGCACCAGAAGTCTTGGCTAAAGAA +ACAGGGCAAGAAAAAGAAAGGAAAGGCACACAAACTGAAAAGAATGAAATAAAATGGACT +ATTCACAGACAGCATGACTGCCTATGTAGAAAATTCCAAGGATTTCTTTTTGTACAAAAA +AGCTCTTAGAATAAGTGAGGTTAAGCAAAGTCAAGAGGGTCCAAGATCAACAACATAAAA +GTGGTCATATTTCTATGGATTCTATCAACATTTGGGAAATTGATAAAGTGAACTGCATCA +AAATTAAAATGTTTGGCTCTGTGAAAGATGCTGTTAAAAGAATTAAAAGGCAAGCTAAAG +ATTGAGAGAAAATATTTGCAAATCACATATCTGACAAAGAACTTGTATTTAGAATATATA +AAGAAGTCTCAAAACTCAATATCAAGAAAATAAACAACTCAATTAAAATATGAGCAAGAC +TTCAACAGATACTTCACCAAAGAGGATACACAGATGGCAAATTAGCACATGAAAAGATGT +TTTACATCATTAGCCACTAGGAAATGCAATTAAAACCACAATGAGCACATTATATATACA +TTAGAATGGCTTAAGAAAAAACTTAACAATACCAGGTGCTGGTAAGGGTACACAGTGATG +TGGCTGGTGAGACTGTAATATGGTACCGCCACACTAGAAAAGACTTGGGCAGTTTCTTAT +AAGAATAAACACACACGGACCATATGACCCAGCAATCCCACTTCTGGACATTTATCAAAA +GGAAATGAAACCGCATGTTCATAGAAAAGCTCATACACAAATGTTTACAGCAGTTCTGTT +CAAACACACAATGGACTTACCGAGGGACAAAAAAAAAACCAAACTATTGATACCTGCAAC +AGCTGGAATGAGCCTCAACGGCACAGTGGTGAGTGAAAGAAGTCAATCTCAAAAGGCTAT +GTACTGCGTGGTTCCATTATATGACATTCTTGAAAAGGTAAACTATAGGAACAAAGAGTA +GCTCAGCAGTTATAAGTGATTGGGAGGGAGCTGAATATAAAGGGATGGTATGGGAAGTTT +TCTTGGAGGATAGAATTTCTCTGTATTCTAACTGTGGTCGTGGTTACACCATCTGCACAT +GTCTTAAAACTCACAGAAATGCACACTGAGATAATCATTCTTACTGTGTATTAATTTTAA +AAGTAAAGGAAAAGGAAAAACAAAATAAAATGACTGCACCAATTTGATTGAAATGTCTTT +TAAAATACCTTTATTTTTAGCCAGACACAAAAGGAGAAACACTGCGTGATTCCACTTATA +GGAGGTCCCTAGAGTAGTCAGTCACAGCGACAGAAAGGGGAATCAGGGCTGGGGAGTTAT +TTAATGGGTACAGAGTTTCCATTTGGGATGATGAAAAACCTCAGGAGATGGAGGGTGGTG +ATGGCTGCCCAACAATATGGATGTACTTAATGCCACTAAACTATACCCTTAAACATGGTT +AAAATGATCAATTTTATGTTTATTTTACCACAATTGTAAAAACTCATGTTCTTCCACAAG +AATAGATTTAGAAAATTGTATTTGTATAAAAATAAAACAATAAAAGAAGTTCAAAAAGCA +AAAAGCTAAAGTCTCTCCCCACCACACTCTCCAGATAACATCACTGTCAACAGCTTGCTG +TGCTTCATGTCAGATGTTCACAATCTTTATCATACACACTGGCTCAGGTGCATGCCGGCT +CAGATGCATGCCAGCTCAGGTGCACGCCAGCTCAGGTGCATACAGGCTGAGGTGCATGCC +AGCTCAGGTGCACACCAACTCAGATGCATATAGGCTGAGGTGCATGCCAGATAGGGTGCA +CGCTGGCTCAGGTGCATACAGGCTGAGGTGCATGCCAGCTCAGGTGCATGCCAACTCAGG +TGCATATAGGTTGAGGTGCAAGCCAGACAGGGTGCACACTGGCTCAGGTGCATACAGGCT +GAGGTGCATGCCAGCTCAGGTGCATGCCAACTCAGGTGCATATAGGTTGAGGTGCAAGCC +AGACAGGGTGCACACTGGCTCAGGTGCATACAGGCTGAGGTGCATGCCAGCTCAGGTGCA +CACCAACTCAGGTGCATATAGGCTGAGGTGCACGCCAGCTAGGGTGCATGCTGACTCAGA +TGCATACAGGCTGAGGTGCATGCCAGCTCGGGTGCATGCCCGCTTAGGTGCACACAGGAA +TAGGGGCTTCTAATTCTGTGATTAAATGTGAAACAGAGGTCCTGGGTCAATTTGCACAAT +CCTTCTGACTTTAAAAGAGTCATGCTCTTTGCTTCCCACAAGAGGCAACTGAAAAGTAAG +TAAAACACATCCCAAGGGTGAAGTCACTGGTGGAGGGTAAAGAACACAAGATGGCAGCCA +CCAAGGGCTGGGGAGTAAAAGTCCTTCGCAATTTCTGACTGTCGTAAGAACTCGATGAAG +GCCAGAAAGGAGGAGGAGATGGCAAAGTTAGCTGGGATTGAGAAGATGATGGAGACAAGA +CACTTACAAGATGGACAGGAATGATCACTGGGCATCCAAGAACAATTTATGAAAGCCAAA +TATACAGCCTTAAAATAGAATGTGGACCTAAACACTGAGAAGCACCCCCCTTTTGTAAGA +TTTGTGACAAAAATTAATTTGAGTGGAGTTAACAGTCCTAACGACATGGTGGACCCAAGA +GCCAAATCACCGCTAGCAAAACGGCAGAATTCATATAGCATTCAAAGATGTCCTGCAAGA +GCTTTGGGCCTAATGATGTCGGTGCTTAATGATGTCTATGGAATATATGAAACTTCCTCA +GCTGCGCGAAGGCCAATGTTACAAGTTAATCAAAAGGAAAAACCCCAGGCCCTTCCCCTT +TTCCCCCATTCAACTTAAGTAGTCTTCATTTCCCACAGTAGTAAATTTTCTAGATACATC +TTGTAGACCTCAAAGTACTGGAGAGGGCCAGGCATGGTGGCTCACATCTGTAATCCCAGC +ATTTTGGGAGGCTGAGGTGAGAGGAGTGCTTGAGCCCAGGGGTTTGAGACCAGCCTGGGC +AACATAGTGAGACCCCATCTCTATAAAAAATGTAAAAAAATTAGCCAGGCATGGTGGCAC +ACGCCTGTGGTCCCAGCTACTCAGGAGGCTGAGGTGGGAGGATCACTTGAGCCCAGGAGG +TTGAAGTTGCAGTAAGCCAACACTGCACTCCCGCCTAGGCAACAGAGCAAGACCCTGTCT +CAACAAATAAAGTATTGGAAAGGAAGCGCTCATTCAACTTATCTTAAGATACTGTAAGAT +ATCTGCCACTTTTCCTAAGATATTGTAAATGATACTACATTTTGAAATATGTAAGTTGTG +CTATAACAACAACAACAACAAAACATCCTAGGCCTGAGCAAGCAGTGCTCCATTCGGAGC +TGACCCAAACCTTAAAAAGGAGCAAAGGCTGGGCACAGGGTCTGACGCCTGTAATCCCAG +CACTTTAGGAGGCCGAGGCAGGACGACTCCTTGAGTCTCAGAGTTTGAGACCATCCTAGG +CAACACAGCAAGACCTCATCTAGAGGTCTAGATGAGGTTTTAGTAGACTAAAAATTTAAA +AACTAGCCAGGCATGGTGGTGCACACCTGTGGTCCCAGCTACTCAGGAGGCTGACATGGG +AGGACTGAAGTTCAAGGTTGCAGGGAATCAGCCTGGGTGACAGAATGAGACCCTGTCTCA +AAAACAACGGCCGGGCATGGTGCCTCATGCCTGTAATCCCAGTACTTTGGGAGGCCGAGG +CAGGTGGATCACCTGAGGTCAGGAGTTCGAAACCAGCCTGCCCAACATGGTGAAACCGTC +TCTACTAAAAATACAAAAATTAGCCGGGCATGGTGGCACATGACTGTAATCCCAGCTACT +TGGGAGGCTGAGGCAGGAGAATCGCTTGAACCTTGGAAGCAGAGGTTGCAGTGAGCTGAG +ACTGCACCACTGCACTCCAGCCTGGGCAATGCACTCCATCTCAAAAAACAAAACAAAACA +AAACAAACAAAAAAACAAAAAGAAGAAAGAAGTGAAGGCAGACAGTCAGAGGGCTACAGA +GACTCCAGGCTGGTCAATCAGTGACAGAAATTTGAGTTCCCTTTCTCAGGTCCTCCCCAG +GCATCCCCCAGAGAAGTAGGACAGAGAGAAGACGGGTACCATGCCCACAGCAGCACTCTG +GGTCCCCCAAGGGCTGCCTTCACGGTCCCCATCCCAGCCCAAAGGAGTTCCAGCCACTCT +GCTGATGCATGGCACCAAGTTCTGGGCTCAAGTCCTCCCACCTCCCCCTTTGGTTGCCAA +GAAACCTCCCTCCAAAGATGTCCAAATTCAAACTGCTGCTTCTAGACACCTGGCACCAAT +AAACCCCGAAGATAAACACAGCCTGACTCATTTACCCAGCCCTGTGCATCGCAAGCATTT +TAGCCATAATTAACCTTCGCTTAAACCCTGTGTTTGTGCTTGAGTTTAGCAATCACCAGC +ATTCGAATCCAAATAAGAACATCACAAAGATTACAGTGGACAAATAAAATATAAACAGAT +CCAAATGCCTCCATGTTCTTAATTACTAGCTATGTTCCTTTGTATACACAGATGAAAGCA +GCAACTAAATAGCCTGCGTAAACTGCGTTTACATGAGTTTTTCTCTGTATGACCAGAAGC +ACTAAAACTCACCTGCAGAACTCCACTGAGCTTCAGAACCCGTGGGTGATTTTTGTTTTT +TCAGTGTGTACACTTCATTATCGTTTTCAAGCCCACCCTGGAAGAGGACAAGGGCTAAAA +CATGAAATATTAAGCCACTCTCCCCCAAGCTACAGACACATGTAGCTTGACAGACACATG +TCAGCTTCTGCCTGACAGACATATGTCCCTCAAAGAAGAGAAAAAAGCCAGACGGATTCT +TCCCACACCACCACGTTCCTCCTGGCCAAGCCTTTCCGTAGAGAAAGGCCAAGCTGGGTT +CAAGACCGGAGACTCTGCTCTCAGGTCTGTGACTGTCAGCCCCTGCAATAGGGGTCCCTG +CTGCAGAGGCCCCTGGTGTCCCACCCTGAAAAGTCCCAGAAAGCACTTCTGAGAGCAGCA +GCTCTGGCTTTAGAACCTGAGGAGGGTGCCTGGGGCTACAGGGAGGGTTTCACAGCTGCC +CTGCTGGCACCATGTGGTCACCAGACCCCTCTTTCTCCCCAGCTCCGGGCCCACCCCGGA +GGAGGCTCTCCTGGGGAAAAGGGTCGAGGTGCAGGATGAGAAAGAACCTGCAGAACCTGC +AGCTGGAGGACAGACCAGCCACAACCTGGAGGCCATCCTGGGCTGCCAGGAATGACCAGG +CTTTGTGAGAACCAGTGTCACAGAGGCTGGGCAGGAAGCCCCAAGGGCCTGAAAGCAGGT +GGGACTGAGACCCATGTCCCCACCCACCTGGGAGCCAGAAGGGGCCTGCTGGGCCCCCAG +ATCCTGAGCCTCAGCCAGTGAGAAGCAGGGAAGGGGACACATGCTGACCACCAGTCCCAG +GAACAAACACCCACTCCTGCCAGCCCAACCACACCAGGACTGGTCCATGGGTCACAGCCT +TGGCATGGGCTCAGCTCCCCACTCCCACCACACGGCCAGTGACCTGAGTCCCTCCTACCT +CTGTGACCAGCTCCACTCTCTCACTTGTTCACCCATCAATCATTCATTCACTCCAACACT +GCACCTGATGGAAAAGAAAGAGAAGAGCCACCTTTACCAGTCCTGGAGCTGGCACCCCTC +TGCATTCCCCTACTGATCCATCAGGCAGCTCCCATCCAGTCCAGACCAAGCCTGCCGTGG +ACCACCAGGCTGTGTTTCTCCCGCCTCGCTGTGACTGTTTACGGTAGAATTCACAGGATG +GCACACAGGTCTGATAAGAGCACGCCAGGCACACGGGAGGCCAATGTCAGCAGGCTCACA +GAGAGCGGGAAACAATGATATGACCATGGCTTGCACAAATATTTTTTTTCCCAGAAAAAG +AAAATATCATGGAGGCAGAGCTCCCAGGCTTTCTGCTAATAAATGCCTCTAGCATGTCCA +AGCCATGTCACATTTTGAAGGAAAATGAAGCAGTTTTTGGAAGGAGGACAACAGGAATGG +TCCCCAGAGGCACCTAAGGTATTACTGATGCTTAAATATGGGGCCAGTGGTGACCGGAAT +GAAGCAACCTTCCTAAGAAGCAGAAGGTCGGCTGAGGTGTGAGCGCAGCTTGCACAAGGC +CCCGGACCTCGCTCCTGGTGCCATTAGAATGTAAGAAGTGCCAACCTTCGGCCACCTCAT +GCTGGCCCGATGATCTCTGGGCAAGAATAACAAGCCCTGCCTGCTCTGGGGCAGGCTTCT +GGGAGCAGGGCAACACCTTCATACAATACACCTTGAGCAAGCTCACACACCTTACCTAGG +GCCCACACTGGTTTATAAAACATAGCATGCCACGGGGCCCGTGCACTGGGGAGCACTGAC +CAGTGTGATGGCTGATGTCACATGTCAACTTGGCTGTGCCACAGTACCCAGATATCTGGC +CAATCATTATTCTTGATACTTCTGTGGAGGTATTACTTTTTTAATGAGATCAACATTTAA +AGCAGAGGCTTTGAGTAAAGCAAATGGCCCTCTGTAATGAGGGTGGTCCTCATCCAATCA +GCTGAAGGCATGAATAGCACAGGCTGACCTCCCCCAAGGAGAAGAGCAGAAAGTTCTGCC +TCCAGACAGCCTTCCATTGAGCTGCAATTCTTCTCTGGGTCTCCAGCCTGCTGTATATTT +TAGACTCGTGGCATCTCCACAATCAGGTGAGCCAATTCCTTGTAATGTCTACACACGCAT +ACACATGCACACACCCATTAGTTTCACTTCTGTGGGGGACCCTGACCGACACAATCAATC +AGGGACATGGCAAAGGTATCACGCCAGGCTCCAGAGATGCCTCCAATCCCCACTTCGGAG +CAGAACCTGACTGCGGAAGGAAGCCCCCATGACCACATGGCACCAACAAAAAGTCATGCC +TGTGAAGGATCTAGGCACATACACAATATTTGGCTGGGATACTGGGCTGACCTGTCCAGG +GATAGGAGAGCCGACATATCTGACCCCAGAGAAACACACCACATCACTGTACTACCATGT +CAAATTCTCCCCAGGCCATTTCACTTTAGACAAGCTGGAGGCATGGAGGAGAGTGGGGCG +AGTTTTATCTTTTGGCTAAAAATACAACTAAGACTTCCGTAAAATAAGTTCAGTAAGCCT +CCTAATGAGAAGAGACTCCTAAATCCAAGAAACTCTCCCAGAATGCAGACTTCCAGCATG +CTGTGCACTGCTATTCTGGAACCTATGAGCACACATGTGCAGGCAGGCACTCACACACAC +ATGCATATATGCACAAGGTACATGCACGTACACACACACACACACAAATGCTCACACACA +TTCACATACACACATGCATGCACCCCCCCACACACACACAAACACACACGGCCTACTAAA +ACACTGCCAATTTCATTTTCTGGGCTCCACCATTCACAGGGGCCATCACATGTCCTGCTA +ATCAATGCCTTGACAAGAGTAATGTACACCAAGGAAAACAGTCAAGGGTGTGGCAGACTG +GAGAGACCTCCACTGAAGGCCCCAGGGACACACAGCACACACAAGGGCACACATGGCTTC +GTAGCACACTGCAGAACATACACATCTATGACACAGTGGTGAGCAAATAAAGCAAGGTGC +ATACCTCTGCGTGGCATGACCGCGACTTTGGGGAAACACCCCCTCTATGGATGTGTGTGT +ACTTATGCATGCACGCATGTGTGTGCATCTGAAAATCGCAGAGAAAAAAATTCAGAAAGG +CAGGTTGTTTATGGCATTTACCCAGCACAATGAAAGCGTTCACTCTTTGCTTTCTGTCTT +CATTTTCTGAGCAATAAAAATGCCATTAAAATAATGGAAAAGTTAGTCAGCACATCTTAC +TTCCTGTTCACACTAAATATCCAACAAGTATTCTTGTAGAAACACTCCTTAAAAGCAAAG +GCCCCACCAACAGAGAGAAAAACTCGCATAAAAAAGATAGAAGGCACCTTTCCTGTTTCC +CCTCTGAGTCAACATGAAGTTATTTTACGAAGCAGAGAGTTTCCACTGTACTCTTATTTC +TACAGCTTCCCACAAAGGCAAAAAGCAGCTGTGGTTTCCATTTTCCTGCTGATAAAGCCC +TGCTGAAATATATCCTGGAGAAGGTGAAAGCCTGCCAGCCCTGTCTCCGCCCACCAGGGC +CACCAGCTCAGCCCGCGCAGTATTTCAATTGCCTTCTTGTGTGCTGTAACAGGTTGAAGA +GATGCAATCTTGTTTGCAAAAAGGGTCTTTCTAGATGTAAGAATCTCAGGATGAGATCTC +CCTGGGTTATCTGAGTGGGCCCTAAATCCAGGGACAAGTGCCCTTATAGATACACTCAGA +GGGAAAGACAGACGCAGACGCCATGTGATGTTGGAGCAGAGACTGGAGCAATGTGTCACA +AGCCAAGGGACACTGGGGCCACACAAGAGGGAAGAAGCAGGACGGAGGCCCCCCTAGAGC +CTCAGGGGAGTGTGGCCCTGCTGACACCTTGATTTTTACTTCTGACCTCCAGAACTGGGA +GAATAAGTTTCTGTTGTTGGAAACCACCCAGTGTGTGGTACTTTTTATGGCAGCTACCAG +ACATTCATCCCTATGTCCCCTGTGCGCCTATGAAAAGGGATTGTTTCCTTCATGGTTCAT +TTACAGAGAAAGCAAGAAAGCCCCCAATACACAGACTATGAAAATGTGCGGAATGAGATG +AAATGAATCATCCTCACTGCACCCTTGTTAGGGGTCTGCCTCTTGTTCACACTCCACTCT +CCCACCCAAAACCTGAGTCCTATGGCCCCCTCATCCTCCACCCCACCCCACCCCACCCCA +AGGCCCTTCCTTCCCCCTCCTTGGGCAGCCACCGCTTTTGTTCCTGTCACTGCTGCTGTG +TTGCATGTTACCCTGAACTCAGCAGCCTGCAACATGTTACTACACTCCCAATTCTGTGGG +TGAGGAGCCTCAGCGGGCCCCAGCTTCAGTCAGCTCATCTCTGCTCCAATGTCCAAGGAC +ACCAAAGCTGACACACCTAATTACCAAGGGCTACAGCTACAGTCCTTGGAAGGCCTGTCC +CCTCACTTATCAGGGCCCTGAGTGGAGGGGACTGAATACCAGGGCTGCCCACTGGAGCTC +CCATGGCTGCCTGTGGAGCTTGGGTTTCCTCACAGCATGGCTGCCAAAGGGCCAACTCCT +TCCTTGGCATCACAGGGCTCCCAGAGCCAGCATCCTGGTGAACAATGGGGAAGCCACATT +GGGGGTCACTCAGCCTCACACCCACCACATTCCACCAATCAAGGCAGTCAGGAAGTAACC +CAGATCCACAGCAAGGGGACAGACACCCTGCATCTCAGTGGCAGCAATGGCGAGATTGGC +CACCATGTTTTAAAAACTACAGCTTTTCGCCCAGCTCAGCCACCAGCTGTTTCCGATTTG +CTCTGAGTTCTAACTCAGTGTTTGTTACTTCAACACCTCAGCCCCGTCCTCGTTGGGCAG +CCTCACCCTCAAGATCCCCTCAAAGCCCCTGTATCCCCTATTGTGTCCGGAATTGGTGGG +TTCTTGGTCTCACTGACTTCAAGAATGAAGCCGTGGACCCTCGCGGTGAGTGTTACAGCT +CTTACGGTGGCGCGTCTGGAGTCTGTCCCTTCTGATGTTCAGATGTGTTCAGAGTTTCTT +CCTTCTGGTGGGTTCGTGGTCTCGCTGGCTCGGGAGTGAAGCTGCAGACCTTCACGGTGA +GTGTTACAGCTCTTAAGGCAGCGCGTCTGGAGTTGTTCGTTCCTCCCGGTGGGCTCGTGG +TCTCGCTGGGCTCAGGAGTGAAGCTGCAGATCTTCGCGGTGAGTGTTACAGCTCATAAAA +GCAGCGTGGACCCAAAGAGCTAGCAGTAGCAAGAGCGAAAGAACAAAGCTTCCACAGTGT +GGAAGGGGACCCGAGCGGGTTGCCAATGCTGGCTCGGGCAGCCTGCTTTTATTCTCTTAT +CTGGCCCCACCCACATCCTGCTGATTGGTAGAGCCGAGTGGCCTGTTTTGTCAGGGCGCT +GATTGGTGCGTTTACAATCCCTGAGCTAGATAGAAAGGTTCTCCACGTCCCCATCAGATT +AGTTAGATACAGAGTTTCCACACACAGGTTCTCCAAGGCCCCACCAGAGCAGCTAGATAC +AGAGTGTCGATTGGTGCACTCACAAACCTTGAGCTAAACACAGGGTGCTGATTGGTGTAT +TTACAATCCCTGAGCTAGATATAAAGGTTCTCCACGTCCTCACCAGAGCAGCTAGATACA +GAGTGTCGATTGGTGCACTCACAAACCTTGAGCTAAACACAGGGTGCTGATTGGTGTATT +TACAATCCCTGAGCTAGATATAAAGACTCTCCACGTCCCCACCAGACTCAGGAGCCCAGC +TGGTTTCACCTAGTGGATCCCGCACCGGGGCTGCAGGTGGAGCTGCCTGCCAGTCCTGTG +CCGTGCGCTCGCATTCCTCAGCCCTTGGGTGGTCGATGGGACTGGGCGCCGTGGAGCAGG +GGGTGGCTCTCGTCGGGGAGGCTCGGGCCGCACAGGAGCCCATGGAGTGGGTGGGAGGCT +CAGGCATGGCGGGCTGCAGGTCCCGAGCCCTGCCCCGTGGGAAGGCAGTCAAGGCCCGGT +GAGAAATCGAGCACAGCGCCGGTGGGCCAGCACTGCTGGGGGACTCAGTACACCCTCCGC +AGCCACTGGCCCGGGTGCTAAGTCCCCCATTGCCCGGGGCCAGAAGGGCTGGCTGGCTGC +TCCGAGTGCGGGGCCCACCAAGCCCACGCCCACCCGGAACTCCAGCTGGCCCGCAAGTGC +CGCACACAGCCCCTGTTCCCGCTCCTGCCTCTCCCTCCACACCTCCCTACAAACTGGGGG +AGTGGGCTCCGGCCTTGGCCAGCCCAGAAAGGGGCTCCCACAGTGCAGTGGGGGACTGAA +GTGCTCCTCAAATGCCGCCAAAGTGGGAGCCCAGGCAGGGGAGGTGCCGAGAGCAAGCGA +GGGCTCTGAGGACTGCTAGCACGCTGTCACCTCTCACTATCAGTACATACACACATCCTT +CTCCCGCTAAAAGTAACACGTCTTGTCCATTCTCCTCCAACCCCCAACCTCTCACTGCCA +TCCCAGAACCTGGGACACACTAGGCAGGCACTGCATGCTCTCCGAGGGGTAGATGGCAGC +AGATTGAGTGGACCCTGTGCAGCCAGAGACAGAAACTGTGAAGCTGAAAAACACCATGTT +AGGAATGACAGGGACGTGCCCACCTGGCCTTGGTGAGCAGGTGGCGGTGGGGTGGGATGC +ACAGAGGGGACAGCTGGAGAGACCCCCGAGGGTCCAGCGAGGGAGGCGGGGCCCATCAGC +AAGCAACAGGAGCTGGTTCAGGGGCCCCTTCTCAGAGGAGAGGGTTCACAGCAGGACTGG +AAACAGGGTGCCACGTGGGAGGTCTGAGACAAAATTAAACCACAGGTGCCACCACGGAGA +CAAGACCTGCCCCAGGAAGTGGAGCCATAAGAACTGGAGGGCCCTTGGTGTCCTGAAAGG +ACAATAAAAGGCTAAAACACAGCCTGTGTGCAAGGATGTTCAAAATATCATTCCTAACAG +CCTCAAACTGGAAGCCGAGAGGGCAGCAGACACCCGTGGCGGATATAAATGTGCCTAAAT +TGTGGCAGACACACACACCGGAATACGTGGTGGCAAGGCAAGAGAAGAAGACCCTGGGTG +AGCTCAAGCCAAATGTCACAGACGGATGCTGAGTGACACGCACGAGGATGTGCTGCAGAA +CCCAAGGCACACAGACTCAAGCCAGCCAAGATTAACCTGCGCTGTGATCAGCTGGGGAGT +GGTGAGCAGGGGGCCCCAGGGCCCTGTGCTCTGCTCCTCTTCCCAGGCATCGCAGGGCTG +GCTCCATTTGTGAAGATTCAAGGGCCGCACACTGAGGCTAGGTGTGCTTCACAGTAAATT +CTGCAAATATCTCACTGCAGAAGGAAGGAGGAGATGGAAAGATGAAAACAGCAAACCTGG +TGAGAGGGTTTCGCTGCTGCTGCTTCCTGTCGATGACCTTCCCTTGACTCCAAGAGGGGA +AAGGAGGCAGGGAGAGGGGTCACCGCCCAGACGGGTGAGGGGATCCACTGCAAAGTAGTG +GGCCATGGAGCCGACCCAGCTGCTCTAAGAAGAAGGCAGCAAAGCCAGTTGAGGACCAAC +CAGCTCACAGCGGTCAGAGCACTTGCAATGTCCACCATCCACTGGCTGGCTGTATCCTAC +TGCCCTCCTGGGACACGTCCACAGAGAATGTGCACCAGCAAGGCCACCAAGCAGGCCACA +CCTGGATCACTCTGACGACCACGAGGCCAGAGTCTCAGACCATGGAATCTGCTCTTCATG +TCAGCTCTGATCAGACAGGCACTTGGAAGAGTCACAACGCAAAGAACAGCACGGGCCACA +CTCGTTACGGTTTACACAGGCATCAGCAACAGCTCTGATCCTCAGGGAAGCCTCCCAGCC +ATTCTCAGCCCCAGCAGCAGAAGGCCCCGCAAAGCTCAGGATAACTGCACTGTAGCAAAT +GTCTCCTGTGCAGCAGGAGGCACACTCTGCCTCCTCCAGCAGCAAGGAGAGGGCCCCCAG +CCCAGCAGTTTGGGGAGGGTGACACCAGCAGGAACGGACTCCCGGCCTGACACAATTCAT +GAATAAGGCTGTGCTTGGCAAAGTGTTTTTCCGTCTGTAGCAACTACAATGTAAGTGCTT +GAAAAGGCTTCAGAGTAGTCCTGACACAAAATGTCTCAGTGGAAGTCTCCAGATGACACC +ATCACTTATTTAGAGAATGCCACTGTGGCCTGAGCATGGTCTCCTCGCTGAGAAAAGAGA +AAGGGGAGAGAGCATGTCTGCATTCTCAGGGCTCCTTCATTTCCACCGCGAGACATCTGT +GCTAAGCCATCTATCCCTTCTGCAGCCCTAAATGTGCTAATTATTAAATGACACTCTCTT +CCAGTTGAAATAAAACCTGTGCCCACTGGCTGGAGTCACAGAGCGGTTACTTGTAAATAA +ATGGAGTCTGTATCTCCCCGAAGGCTTGATTCCAGGTCCTGCAGCGACTGGTGTCTATTT +TAAAAATCGCCTTCTCACCACCTCTCTGGTTTCGCCAAGCTGGCAAAAACCAAGCCCTGC +TCCAACCGTGCTCTTGTGGAAGGAACTGGAACATGAGGATGGCAGATCCCTGCACAGAGA +GACCTCAGCCCCACAGAACATCCAGGACGCAGCCGCTGCTTACAGGCAAGACCAAGGGAG +CCAGGCGGCTTCCCAGGATTCCACATTTGAAACCCAAGCCACTGCCCTCAGCATTCAAAG +ACAAGCTAGATATCCAATTCCACCTGCTCAAGAGCTCTGCTTTGACCCAGTTTTCCTGCC +CTGTTGTTCTCAGGCTTGCGGTCCAACACCAGCCCCTGGGGTAGGCACTGTGCTGAAGGC +TCTAAGGCATGTCCAGCCCCAGAAATGTGGGGATTAGCCTCACTGAGAGGAAAATCAAGC +GGTAGAGGAGTACATGGTCAAAGTCAGCCAACGTGAGAAATAAGATAATAATACATAGTG +TACACACATTGACGTCACGCTAAAATTTTTACATTTCCATGCAGTTACACATAGGGCCAG +ATGTCACATGGGGGTCAGTAGTTCTCAATCTGGGGGTTGCAAACACAGTTTTTCAACAAA +TATAATCAAATAAAAATATCAGGGGGTGTCACAGATAGTTAAGGGCGGCTGTTATGAGCA +AAACTTACTGGCATGTGTGCATCTGTGTGCTGTGTGTGTGTGCGTGTGCTGCCTCACAAT +ATAAAATGCATGTGGGTCACTGTCAGCGTCTGAAGCCAGCCAGGCATGAGACACCCACAC +AGCCAGGCTGCCTGATGGTCAAGAAGCTTTTGTATTGTAATAAAAAATGTTTTAGCAATA +TGGTCCATGCACTGAAACCTTCCTGAGGCTTGGTTTCAAACATAACACTGAATTCCACAT +GCATCTCAGTTCAAACGTGGGCAAGAAGGGATATTACAGGAGTCATCTCATTTAATAATC +CTACAGTCCCCCAACAACCACTGAGGGACAACCCCACTAAGGAAGAGGGCGGGCCCCACT +GAGGCTGCGCACAAGCTGGCAGGCACAGAAGGGCTTCCGGGCTCCCCCAGGAACTGGAGC +CTTAAAGAGGACGCCGCGGCCACCCCGCCCTGCAGGCCCACCTGCAGCTGGGCTGCATCT +GGGAGAGGCAAGCGAGGGGCCGGCCAGCTTCACTGCCTGCATGCCCTTTAGGAGCAGAAC +AAGCTGCAAAACACCCACCTGCTCTGGGAACAAGGCACGCATGACCAGTCTAGGAAAAGT +GTGCAAAGCTCTCAAGACTCCGATGCATACGGGGTATGTGTGTGCTGTGTGTGCTGCGGC +ACGTGCAGCATATGACTGTGTGGTGTTATGTGTGGGGTTTGATGTGTGGTGTGTGTGGTG +TGTATGTGTACAGTGTGTGTTGTGTGTGTTTTGTGTGTGTGTGTGGCATGGTATGTGTAT +GTACCACGTGGTGGGTTTGTGTAGTGTGTGTGGTGTGTATGGACTGGGTGTGTGGGGTGG +GGAGGTACGTGTATGGTGTGTGTATACATGGTGGGGTATGTGTGTAGTATGGGGTGTTCC +GTGGTGTGATGTGCGGTGTATGTATGCAGTATATATGTAGTGTGTGTGTGGTGTGGTGTG +TGTATGTAGTGTGGTGGCTGTGTGTGTGGTATGTGATGTGGTGTATGGATGTGTTGTGTG +TTATGTGTGTGTGGTGTGGCAGGTATGTGTGAAGTGTGTGGTATGGGGAATGTGTGGTGT +GGTGTGTGGATGTATTGTGTGGTGGGTGTGTGGTGTGTGGATGTATTGTGTGGTGTGTGT +GTAATGTGTGTATACTGGGTGTTTGTGGTGTGGGGGGTATGTGTGTAGTGTGTGGTATGG +GGTGTGTGGTGTGATGTGTATGTGTGTGTTGTTTGGTGTGTGTGTACTGGGTGGGTGGTG +GAGGCATATGTGTGTAGTATGTTGTGTGTGTGTGTGTGTGTGTGTTCCAGAGCTACATTT +TTCAACCTTTTCCTTTGTATTTCTCCTTTGTGATTTCCATAACAAGTATTGTTGCAGAAA +ATCAGAGAAATGTAGACAAGCACCAAGGAGAAAACAGAAGGCACGTCATCAACTAAACAT +CTGACTCGCATTTTGGACATGGTCTAGTGCTTTCTAGGCAATTGTAAGTCCTTGCCATGC +ATGTTGGTTCACAAACTGTTCTTAACACATGATGTATTATGCTGACTTCTCATCTCATTA +GGCATATTTTACACTAGATTTTCAAAGAGTGACCAATGTTACTATGGCACATCCTGCCTA +ACTATTTCACTGTCAGTAGCTGCCCAGGTTATATCTGGATTTTCTATTTATAAACACTGA +GAAACACCCTTTTCAATAAATGCTTCTTAACATTCATGATTCTTTAAATAAATGTCTAGC +TCATTCAGACTCCAATGGCCAAAGGGTACATGTGCCTTAAAATCTTTAAAACATTAACCG +GGCTGGGCACGGTGGCTCACACCTGTAATCCTAGCACTTTGGGAGGCCAAGACGGGAGGA +TCACCTGAGGTCGGGAGTTCAAGACCAGCCTGACCAACATGGAGAAACCCCATCTCTACT +AAAAATACAAAATTAGCCGGGCATGGTGGCGCATGCCTGTAATCCCAGCTACTTGGGAGG +CTGAGGCAGGAGAATCACTTGAACTTGGGAGGCAGAGGTTGCAGTGAGCCAAGATTGCAC +CATTGCACTCCAGCCTGGGCAACAAGAGCAAAACTCCATCTCAAAAAAAAAAAAAAAAAA +AAAAAAAAGAAAAAAAAAAAACCACTAACCAACTGCCACCTCCTAGTGCATGCATTAGAT +GCTGGACCTCAGTATAGAGCATCGAATCACAACTCCTGGCTTCACCACTTCTTGGCTGAG +CGGCTTCAAGAATAACATTCTTATTCTCTCTGTTCTCACCTGTAAACAAGAGGGGAGAAC +TGACCCAGTCTTACAGGACTGTGGTCAGAACTCCATGAGACGGATAGAGTTTGGCATATC +ATTTATAACAAGGTCACCATGAACGTCATCTAGCATTCTTGTCCCATAACTTCTTTCCCT +TGTTTCCAATCTGTCTTTCCAATTCATCACTCTGAAATGCCAGAGTTACTCCTGAGACAT +CGATCTGATTGCTTTATTTACTGCTCAAATACCTGCATAATTATGCTGAGTGAAAGAAGC +CAGACTCAAAGGCTACAATCTGTATAATTCCTTCTATATGAAATTCTGGAAAAGCCTAGA +GGGATGGAAAACAGGTCAGTGGTTGCTAGGTCTGGGGAAAGGAAACTGACTACAAAGGGG +CACAAGACGGAATTTTTGGAGTTATGAAAATTTTCCATACCTTGATTTGGTGTGGAAATG +ATTTGGTATGGTTATATTTACCAAAACCACATGCATTAACCAAAACTCACAGAATGGTAC +ATTTAACAGGAAAGATTTCACTGTATATAAAATTATAGCTCAATAAATCACACAAATAAC +CAGAACTGACTCAAACAGAAACAGAAAATCTTCATAGTCCTATGTTAAGGAATTGAATTC +ATAATTAAAAGCCTCTCCATAAAGAAAACCCCAGACAGGCTGGGCACAGTGGCTCACACC +TGTAAGCTCAGCACTTCAGAAGGCCAAAGCGGGAAGATGGCTTGAGGTTAGGAATTCAAG +GCCAGCCTGGGAATCATAGTGAAACTCTGTCTCTGCTAAAATTCAAAAAAATTAGCCAGG +CATAGTGGTGTATGCTTGTAGTCCCAGCTACTCTGGAGGCTGAGGCAGGAAGATCACTTG +AGCCCAGGAAGTCAAGGCTGCAGTGAGCTATGATTGAGCTATGATTGTACCACTGCACTC +CAGCCTGGACAACACAGTGAGACCTTGTCTCCAAAAAGGGAAAGGAAGGGAAGGGGAGGG +GAGGGCAAGAGAAGCCCAATCCTACAAAGACTATTCAAAAATAGTAAGAGGAACCACTTC +TCAAATCATTGTGTGGGGCAAACTTTACTTTGATACCAATATAAAATACAGTACCAGAAA +AGAAAACAATATCCCTCATGACATAGCCACAAATATCCTTAATAAAATTGCAGCAAATCA +AATCCAGCAATATATAAATATATATATATAATATATAAAACAAATATATAAAAAAGATAC +ATAATTACCAAGTGGGATTTGTGCCAGAAATGCAAGAATGATTTAACATTCAAAAGTTAA +CCAGTGTAATTCACCATATTTACAAACAAAAAATGAAAAACCCTATGATCATCTCAACAG +ATACAGAAAAAGTATATGAGGAAATTCAACACCTACTCATGATAAAAGCTCTCAACAAAT +TAAAAAACTTCCACCGCCTTGTAAAAGGCACTTCATATCTTTACCTAACATCATACTTAA +CAACAACAACAACAAAACTTGAAATTCTTCCTTCCTGATATTGGGAACAGGCAAGAATGT +CCACTTTTATCACTTCTATTAATCATTGTACTGAAAGTCCTAGAAGTGAAAGAAAAGAAG +AAAAAGGAGTAAAAGGCATTCTAACTGGAAAGAAACTGGTCTTTATTCATAATCATCAGA +ATTATCTATATGAAAGATCTTGAGGGACTACAAAAAAAGCTACTTAAATAGCGACTTAGC +AAGGTTCACAGGATAAACAAAAAATAGAAAAAATCAATTGTATTTCTATATATCGCAATT +AACAACTGGAAAATAAAATTTTTAAAATCCATGTATAATAATATGAAATACTTATGAGTA +AATCTGATAAAACATGTGCAAGACCTGTACACTCAAAACTACAAAACACTGCTGAAAGAA +ATAAAGGAAGATGAAAATAGAGGGAGATTCCATGCTCATTGGTCAAGAGACCAAATATTG +TTACAATGTTTTTTCCCAAATTGATCTAAGGAGTTAATACAATTCTGGCCAAAATCCAAG +CAGGCTTGCTGTAGAAACTGACAAACTGATCTTAAGTATATAAGAAAATGCAAAGGATCT +AGAACCGACACTACAATTTTGAAAATGAAGCAAAATTGTCATGCTACCTGACTTCAGGAG +TTACTACAGAGACAGTGTGATACTGGGACCTATGAGGAATAAGCCATAATGGAACAGAAC +AGAATCCAGAAACAAAGGCACACAGATATGGTCAATTACTTTACAAACATGGTATCAACA +TAATTCACTGGAGAAAGAAGAGGCTTGCTGTTGTTGTTTACTTTAAAACAAATGGTGTGA +GAACAATCGGAAGTCTACATGTAAAACAATGAACCTCAATCCTTAGCTCTTTCCATTAAA +AATTAACTCGAAATGGATCACAGATCTTTTTTTTTTTTTTTTTTTTTTTTTTTTGAGAAC +AGAGTCTCACTCTGTCACACAGGCTGGAGTGGCTGGAGTGCAATGGTGCGATCTCAGCTC +ATTGCAACCTCCGCCTCCCAGGTTCAAGTGATTCTCCTGCCTCAGGCTCCCAAGAAGCTG +GGATTACATACGTGCACCATCACATCCGGCTAATTTTTGTACTTTTAGTAGAGACAGGGT +TTCACCATATTGGCCAGGCTGGTCTCAAACTCCTGACCTCAGGTGTTCCACTCACCTCAG +CCTCCCGAACTGTTGGGATTACAGGCGTGAGCCACCACGCCCAACCAAAATGGATCTCAG +ATCTAAACATAAAAGCTAAAATTACCACATTTTCAGAAGAAAACACAGATAATCTTTATC +ACTATGGATTAGACAAAGATTTCTTAAATAGGGTACAAAAAGCACAAACCATTAAAACAA +CTTAAAACCAAAAAGTCTGCCCATTGAAAGATATAACGGATAAAAAGGCAAGCCATAGAC +TGAGAGAAAATATTTGCAATACAAGTATCTGACAAAAGGTTTGAGTCAAGAATATGTAAA +GAACACCTACAACTCACATATAAGAAGACAACCCAATTAAAAAGTGATCAAAAGATCTGA +ACAGACACTTCACAAAAGAATATACACAAATAGCTAATAAGCACATGAAAAGACGCTCAA +CTAAAACTGCACAGATACAGCACTACCACATTTCCACTAGAATAGCTAAAATTAATAAGA +CTGACAACAGCAAGTGTTGGCACAGACGTAAACCAACTGCAACTCTCATGCGTTAGCAGT +GGGAACGTAAAATGATACAACTGCTTTGCAAAGCAGTTTGCCAGATTTTTAATCAAGTTA +AACATCTACTTACCATGAAACCCTGTAATTCCACTTGTAGGTAGTTACGCAGGAGAAATA +AAAACATATGTCCACGCTAAGATTTGCCCACGAATGCTCACAGCATGTCTTATATCATCT +TTTATTGTGGTAAAATACTCGTAAGATAAAATTTACCATTTTAAAGCGTATAATCCAGTG +GCATTTAGTACATTCGCAATGTTATGTAACCATCACCCCTATCTAGTTCCAGGACCTCAA +AAGGAACCCCAATGCATATTAAGTGTTCACTTCCCATTCCCCCACCTCCCCAGCTCCTGG +CAACCACTAACGTGTTTTCTGTCTGGAAAGATCTGCCCATTCTGAACATTTCATATCAAT +GAAATAATACAATATGCAGCTATTAATCTGTGCCTGGCTACCTTCACTTAGAATAATGTT +TTTGAGGTGAATTCACATTGTAGCATGTATCAGCGCTTCACTCCTTTTTATGGCTGAATC +ATAGGCCATGTATGAATATACCACATTTAGCTTACCCATTCATCCACTGCTGGACATCTG +GGTTTCCGTCCTTTGGCTACTGGAATAGTGCCACTGTGAACAGCCGTGTATAAGTTTTTG +TGTGAGTCCCTGCTTTCAATTCTTTTAGGTATATACGTAGGAGTGGGAGTGCTAGGTCAT +ATGGTAATTCTGTATTTAACTTTTTGAGGAATCTCCAAACTTTTTTCCAAAACAGCTACA +CCATTTTACATTTCTATCCGGAGTGTATGAGGGTTCTAATTTCTCCATAACCTCACCTAC +GCTTGTTATTTCCCTCCACCCTCCTTTTTTTTTTTTTAATTAAAGCTAGTAGGGTGCGAG +ATGGTATCTCACTGTGGCTTTGATTCACATTTCCCTAACAACTAATGATGTTAAGCACCT +TCTCGCATGTTTATTGGCCGTTTGTAAATCACCTTTATTGACACATTTACCCATGTTTTA +ACTGGCAGTTTTTGTGGTTGAGTTGTAGCTCCCAGCACTTTGATTCACAATAAACCCAGA +AGAGGAAACAATTCAAACTTCCACCAACTATTCAGCAATAAAAAGACATCAAGTGCCGGT +ATGCACAGCAACATGTAAGAATCTAAAAAACATTATGCAGAGTGAAAGGAGCTAGACAAA +AGAGTATGCAGATGGTCCCCCATTTACAATGGTTTCATTTATGATTTTTTGGCTTTACAA +TGGTGTGAAAGCCATTCGAATCCAGTAGAAACGGTACTGCGAGTATCCACACAACCATTC +TGCTTTTCACTGTCAGTGTGGCATTCAATAAATTATATTCAACACTTTATTATAAAAAAG +GCTTTGTGTTAGATGACTCTGCCCAACGGTAGGCTAATATAAGTGTTCTGTGCACGCTGA +AGGTGGGCTAGCCTAAGGTATGCTTTTGGGCGGGTCAGGTGTATCAAACACATTTTTGAC +TTAGGATATCTTCAACTTAATGATGGGTTTATGATTAGGATGTAATCCCATCACAGGTCT +AGGAGCAACTGTCAAATATATGCTCCCACTTTGAAAGTATTGAAGAAATAAATCCAATCT +ATAATAATCTAATCTATGCAGATCAGTAATTGCTGGGAAGAGGGGGTTGAGTGAAAAGGG +GCAACAGGGAAATTTAGGGGGATTCTCAGGGCCATATGGTCTCTGTGGCAACTGCTCACC +TCTGCTGCAATAGCATAAAAGCAGCCACAGATGATTCGAAATAAATTGGCCCAGCACACT +TGACCTGCAGGCCCAAGCTTACCAAATCCTGGTCTATATCCTGATTATGGTGTCAGTCAC +ATGGCTATCTACATGTGTCAAAACTCAGTTAGCTGTGTTTGAAGTGAATACATTTTGTCA +TAATTCATGTCAATAAAACTGAGTAGGACAGCATTGCCTCTAGTGGGACTCCACGTGGAA +AGCACCCCAAGTCTAAGGTGCATCCAACCTGGGGACCGCTACTTTCTCCCCATGGGCCTG +TCCCACCCACTCCCAAGTGTGGGCCTGTCTTAGGGCAGCAGTTCAAAAGCCTCTGGGGAG +CCTGTTAAAACAGATGGCTGAGTCTGGGCACCGTGGCTCACACCTGTAATCCCAGCACTT +TGGGAGGCCGAGGAGGGTGGATCACCTGAGCTCAGGAGATCGAGACCATCCTGGCCAACA +TGGTGAAACGCTGTCTCTACTAAAATACAAAAAATTAGCCGGGCATGGTGGCGTGTGCCT +GTAGTCCCAGCTACTCAGGAGGCTGACGCAGGTGAATGGCTTGAACCCACGAGGCAGAGG +TTGCAGTGAGCTGAGATCACACCACTGCATGCCAGCCTGGCGACAGAGCAAGACTCTGTC +TCAAAAACAACAACAACAACAACAACAACAACAAACAGATGGCTGGTCCCACCCCACAGT +TCCAGATGCCAGGGAGACTCTGCATTTCCCAGGGGTGCAATGCCGCTGGTGCGGGGACCA +CTCTCAGAGAAGCACACTCCCATTCCTCCAGCGTTCAGTCCATGTGGAACTGAGAGTCAG +TGTTGCAGGCAAAATGCAGGCCATCCCTGCCCGGCCTGGAGACAATGCCAGCACTCACTA +AGGTGATGAGGAAAATGCTCACAGTCCACCAGCGATGGGACAGCCCCATGCATCTGTGGG +CCCCGGGGCCAAGAGGAGGCACAGCACACACCGAGAGTCAACAGCAGCTCATGGGGATCC +TTCACCAAAGGGGCGGCCCCAGCCAGTCTCTGTCCCTCCCACCCACCTCACGGCTTCCTC +CCACTCTGCTCCATCCTTCTCTTCAGGATGCAACCCTTCCAAGCGGGCCTCCCTCAGCCC +TATCTGCCCATGACCCCCCTCCACTTCCCCACTGCCCTTCACGGCAGCAAAATTCTTGAA +AAAGCAATAGGGTCCTGCTGTCCCAAATTCCCCTCCTTCCTTCTCTCAAGAAACTCACCC +CATACTTCAGCCCACCATCCCAGACCACATGGATAAACCCCAGGTTGTCTTCGGTTCTCA +CCTTCGTGACCTCCGCTGTCACCCTCCCTCTCATGCAAGCTGCATGTGGCCTCCAGGATG +CCCTCAGAACCCTCTGGTTATCCCCTACCTCGCTGGCCGCACCTTCTTGGTTTCTTGTTC +CAGGCTCAGTCCTCGGACCTCTTCTCTTTTCCATCTACCTCAACTCCCTAGTGGTCTCAT +CCAAACTCCCTTTCAAAATGTCATCTCTATAGCTACAATATATTGCCAAGATTAGGGTCC +CAGCTCAGAGCACTCCCCCAAACTCCAGATCCCTTCCTCCAACTTCCTCCTCCCCACCTC +CACTGGGACACTTCAGTAGGACTCTCACCTGTACTATCTTGAGAGCCACACCATCCCTCT +GAATCCTCACAACTCCTCCCCTGAAGACCTCAGTCTCAGAGTGATGGCAACTCTACCCTT +CCAACACCCGATCCAAGACTCTTGGGTCATCCTGGACCCCTTGCTTGCTGCAACAGCCCT +CATGGGATCCATCACAGTCCTGTTGGCTCCGTCTTCGCAGAACACCTGCAATCAGCCTGC +CTCCCACCCGAGGAGACTGCCCGAGCTCCTGCAAGGCCCGCCCCGCACCGCCCTCCTACC +ATTGCTCATGTGTGCCTAAGTGTCCCCTCACCACTCCTCACCTCCCCTACATCTAGGGCT +CAGCAAGGCACAGGGGCCACCTGATTTTAAATCACAACCACCCTCTCAACAAACCACTGG +CCCCTTAAGCGGCTGGACCTAGAACTATCTATCTCCCCTCTCATTAGCCTCCCATCTCCC +TCCACTTGACCATATTCCCCGGCACCCCAGCCATGACTGACATTCAATACGTGTTTTCTG +GGGAAGCAGTGAAACTTCATCAAGTGGACAAGTGCAAGAGTTGGGAGGGCCCTGAAAGGT +AAGCAGTTCCTTCAGGTCAGGAACCTAAGACAAAGGAGCATCACCCACCAGGGACCAAAC +GTGCCAGCACTGTGACCTGCCCAGATGGCTCAGCTCCTTGTGGGCCCTCAGAAGGAGGGG +GCTATACAGGATAAGTGTGATCCAGATGGGGGAAAAGAATGTGCATCCACCCACTGGGTG +GTTCTGTGCAGGCGCAAAGGCAGGCGGCTCCTGGCAGCACAACAATGAACATGTGCCAAG +ACCCTCAGCCCTCAAAGATGGCCCAGGGCTCAGAGCCCCGCCACAGCCCTGCTGCAGCAC +TGGGCTGTGCCCTCACAGCACATGGGACACACCGGTCAGGAACAACAACAAACAAAAGCT +CCTAAACTCACAGTGAGAACCAAGTGGGTCAATTGCAGGCCTAACGGGAAACTTTCTGTC +CTTCCAAACAAAGTCAAAACACACACACAAATCAGAAGGCCTAACAAACACCCACATTCT +ACATCAAGGCAAATTACGTTCTGGCTGCTCAAGCAACTCTAATTTCTTGCAACAGATCAG +GAAAATACAAAAACTGTTACAATTCTAAGCAATTTCTACTTTTTACTTTGTAGACTTCTA +TGCAGCACGCATCACTTATGTTTTTGCTATAGCTTTAGGTTACTTAACATATCCTTTACT +AAATGGAAGAAGAAAACAAAGACACCACAGGAAATGCTGGAACAAGCCCCAGGTCCAGGT +CAGCCAACCAGCAATGGGGACCCCTCTGGCGCAGGCTCCAGACCAGACTTGGCCTTTGTT +TCTGTACTGAGTGTAAGGATAACCCTTCTGTGGCTGGATTGTACTATTATTTAATTGTCA +GGGTCTTTGTCTTGTCTCCCCTAATGCTGATAGTAGCATATTGATTTCTATCCTTCATAG +CCCACAAAGCACATATTCAGAGGATCAATAACTATTGATTCATTGATTGCCTCATGGAAG +CCAATTCATCTGTTATTAAGACGTGTAGAAACATGAACTTCCACAAATCAAATTCTATTT +AAAACGCCAGAGGAAAGTATATGACCTAATGAAGACCACTTTTTGAAAATTCATTTTGAT +ATTCCAAAAATAATTCCTTGTAACAGAAACAAACCATACATAAGTACAAAAAGAAGACAA +AGTATAGGTTCCCTCTTCCTCTTCCCTCTCCTCCCCCAACACACACTCACTCACATTCAC +ACACGCCCCACCCTTTGCTAACTGTGGAGTGCTGCTTTCACTCAGGGCTGAGTCCCTAGA +GCCTGGGGCAGCGCCTGGCACCAGGTCCACATAGGCGGCTCCATAATGATCTGCTGAATA +CCAGGTGTGTGTCCTTCCAGATGGGCTTCCGTGCTGAGCGCCTGCACTTGTGCATGGAGA +GGGCACATTCTCTATAGTCTACACTAAGGAGTGACATTTCTACTTAATAGATTGGCATAT +CTTTTAAAGTAAACCTTTGAATGATGCCATCATGAAGTAAAGAATCCAATGGCATGTTTT +ACAGGGAGGAATTGGAGATCTCCGATTATTATTAACTTTTCATGATGGAGAATTTTCAAA +GTGCATGCAAGTAGGCAGAACAGAACAAAGAACCCAGGTACTCTCATCCAGACCCCAAAC +TGTCCACTCAGACCATCTCGCCCCTTCTCATCCCCTCTGCTTCCCCACCCCACACTAATC +TGAGGCAGATCCCAAACATCATTTCATCTACCAACACTCAGTATCTATTGCTAAAGGGTG +AAAGTTATTCTAACATAACCACGATGCTGTGATTAAGGAATTCCTTAAAATCATCATTCA +CTCCACAAATGTCCATGAGACACATCAATAGCCTAGTTTTCAAAGGAGTGATGCTTGGAT +CAAATGCTGATCCAAGTGACAGCCTGGATCAGGCTTTGATCGAAGCCAGAAATCTTGGGG +TGCCACTTAGATGTGATCCAGGGCAGGGATGCAGTCATTGCTTTCATGGGCAGCATCTGA +AACTTCTGGACCAAATAACAGGACCCTGCCTGCCCCCCACTGAGGTTTGCACAGGTGCTG +TGGGAAGGCGGCTGCTGATGCCCCAGGGGAAGCAGCAAGGCAGTAGAAAGCTGGGGCCCC +TGCTGTGACACCCCCAGCTAAAGGCAAATTCGCTCAGGGAGGGTCACAGAAGCTGAAAAG +TGACCCACAAGCAGCAAAGCAATTTGCTTATCCCAAGGATCGCCTTAACTAGTGCACCTA +AAACACCACCCAGCTTCCAGGGAAGGCCCTGGCACACCCTCTCCACCTGACTGAATCAGC +AGCTATCTCCTCCAGCAGCCCTGGACCCTGGACGGCAATGGTGATGGGGATGGGGATGCA +ATGGGCAGGGCTGAGGAACTGCACCTGCCAAGCCCAGGGCGGACCCTGGCCCAGGGAAGA +GAGGACCCACCCCAGCTGCCTCTGCCACCTCCCTTCTCACCTTCTAGTCTTCTTCCTGGA +ATTGTCCAAGTTCAAAGAAGAAATAACTGCCCTGGTTGGGAACAGCAGGCAGCAGCCTTT +CTCTCAGCAACTAGGCTCGACAATCAGCCGACGGCACGTTTATTTCTATATTTTCACGTG +GCAAGTTTCATCCCCATGGGTCCTAGCTCCAACCCTGGAGCTCTGGCTCCAGGGGTCAGG +AGGAGAATCTGCAACCACCCTCCTGGACCCGCCCATCCCTCCCTCCCCAACAGAAATGGA +ACCAAGAGAGGCAGAAGCCTGAACAGCCTCAATGCAGAAGCACAGAAGATAGAGAAAACC +ATTGATCTTTGCAATGCATTATTGATTTTGCTGTTGTGCTGTCAGCAGCGGACGTTCCCT +CCCTCCTCAGTCAAAGCTGGCCATTAGCGTGCACTCCCAAGCTTTGGCCTAGACACACCC +GCTTGGTGTGGGGAAAGCGGCTCTAGGTAACATCTGCCTCCAGCGGTCCACATGGAGAGG +ACTGTCCACAAGTGGATGATGTCACCAAGGACATCTCCCTGGCCCCAGACCCACTGGATA +TCAAATGCAACATGGTCGCTGGTCTTGCACTCTAAACCTCAGCCCAGGACCCCAGGCACT +CAGGGGGGTCTGTGCAAGGCTGCATTTTCAACAGACTCTGGGTGTGCTTCTCAGGAGGTG +GGCCCCCTCCCATGGAGTCCCTCCCTTGTGCTGTGCTGCAAGACCTTGGGCTGGCATGGC +AGCTGGGGCTCTGCATCCCCACGGTGGCCTTTTGCCTGTCTGCACTCTGAAATACAGCCA +CTGAGTTCCACCGTCTACCAACTCCTAAGCGGCCCACCCTCCTGGGACCCCAGGGCTGCT +CCTGGCACCAGTGATGTGTTTCTATTTCTTTGTTTGACTCGCTGAGTGTACCACGTACAC +TCTTCTCAGTCTGAAGGTCTGGCCTTATGGGAGGGCAGTCTTTGCTCACAGAAACAGGCC +AGTGCATCCCTCATCTTCCCACCCCAGCCTCCCTGGTGGGTATGCTGAGCCCGCCTGCTT +TCTTCTTCTGGCTGACGACTACCAAGACATGATATACGCAGACACCAACTGTCAAAATGA +CAATCAGGGCATTATCATCTCTACCAGAATCCTGCCCCTGCACTGGCCAGAGCTGCCTGT +TTCTGGGACACAGTAAACATTCCCAAATAACCTCGCCTGGGCAGCCAGCAGGCAGGCCCC +AGGCCTAGGACACATATGAGGTGACAGGCCACTGGTGTCACGTCACCCCCAGGAAAGGAA +ACTTCCGTTCCGTGGCGCCTGGTGGATTTGAAAAGACTCAGAACAGCAGGGTGAGATGCT +TGGCCCCAGGCCCCACGTCCAGCTTGGCCTTCGGGGGCCTGGCCACCCACGAGCCTGGGA +TGTGCTCAACACAGAGTGAGGTTTTCAAAACAAAAGCAAAGCAACTTCATGTGGAAAACC +TTCCGGAAAGCAGGACCCAGCCCTCGACACCAGGCCTCATTTGACGCAAACTGCCCACTT +ACAGACTCCCATTCACCCACTCTCCCACCTACCCCCCAAAATACTAAGCCAGAAAATAGA +GGACAACCACGAGTTCAACTCTCCTTTACACGTTTTTACTGGCATAACCCCAGTAGAGCC +AGCCCCTTGCAGCTCACTAGGCGGCTGCAACAGGTGCAGCCCAAGCTAAGGCTTGTGGTT +CTCCTGGGCTGTTCTAGAATAATGCAACCAAAACCCGAAAGGAAACCGAGGCCTGCAGCA +CTCACTGCCAAGGCGGCGACCTGACCACTGCGGCCCAACCTGCCCCACCTGTCTGAGTGC +GCGGCGCCGGGTCCAGTGCACAGGGTCCGCGGCCTCCGCGACCAAAATAGAAGCCCGCGG +GGGCCCGGCCAGAGCCCGGCTGGCCGGAGTGGGGCCTGACCTGGCGGGGCCGGACTGGGC +GGGCCGGGGCGCGACGGGGCCTGGCCGAGCGCACCGCCCCCTCCCTGGCCCGGGTATGCA +GCGCGCCCCCGCTCCCCCGCGCCCAGAGGAGCCACCTGCGCGCAGGGACTGGGGAGGCAA +CCGGGAAGGGGAGAAGGCCGGGGAGGGATAGCAGAGAGGTCCAGGGGGTCGGAGGGGTCC +GGGTAGGTGTCTCTGGGAGGCGTCCCAGGAGGGGCCCCGGGGGGATCCAGGAAGGAGTCC +AGGGGTCCGGGGATCCCAGAAGGAGGCTCCTGCAGGGGTTCGGGGAGGGCCCCGAGGGTC +CGGTGAGGAGCCTAGGGGTGTGGAGTGGGGGCTCCGCGGAGGGTCCAGGCCGCCCCCAGC +GCACCTGCCCGGCCCCGCGCGCCCTCCCTCCCGCGCCAGCCCGGCCGCTTACCTGCAGCG +CGCGTCCTGCCCGCGGCGGCTCCCGGCCGGGCGAGTTCGGGCGCCAGGAATGGCGGCGGC +GGCGGCGGCGGCAGCGGCGGGAGGCGGCCGGGCCGGGGAGGGGGTGGCGGGGAGGCCCGG +CGGCGGCAGCGGCGGCTGGGATGCTGCGGCGCGCGAGAGCGCTGAGGCCGGCGCGGGGAC +GGAGTGCGCGGGGCGGGCGCGCAGGCCCCTCCTCCGCTCCCCCT diff --git a/test/csq/ENST00000420670/ENST00000420670.fa.fai b/test/csq/ENST00000420670/ENST00000420670.fa.fai new file mode 100644 index 0000000..f5eb6a4 --- /dev/null +++ b/test/csq/ENST00000420670/ENST00000420670.fa.fai @@ -0,0 +1 @@ +9 137384 23 60 61 diff --git a/test/csq/ENST00000420670/ENST00000420670.gff b/test/csq/ENST00000420670/ENST00000420670.gff new file mode 100644 index 0000000..45db4e9 --- /dev/null +++ b/test/csq/ENST00000420670/ENST00000420670.gff @@ -0,0 +1,11 @@ +9 ensembl_havana gene 21 137364 . - . ID=gene:ENSG00000187764;Name=SEMA4D;biotype=protein_coding;description=sema domain%2C immunoglobulin domain (Ig)%2C transmembrane domain (TM) and short cytoplasmic domain%2C (semaphorin) 4D [Source:HGNC Symbol%3BAcc:10732];gene_id=ENSG00000187764;logic_name=ensembl_havana_gene;version=7 +9 ensembl_havana transcript 44688 136666 . - . ID=transcript:ENST00000420670;Parent=gene:ENSG00000187764;Name=SEMA4D-015;biotype=protein_coding;havana_transcript=OTTHUMT00000342408;havana_version=1;transcript_id=ENST00000420670;version=1 +9 havana CDS 44688 44690 . - 0 ID=CDS:ENSP00000405652;Parent=transcript:ENST00000420670;protein_id=ENSP00000405652 +9 havana exon 44688 44933 . - . Parent=transcript:ENST00000420670;Name=ENSE00001755185;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001755185;rank=4;version=1 +9 havana five_prime_UTR 44691 44933 . - . Parent=transcript:ENST00000420670 +9 havana exon 57290 57352 . - . Parent=transcript:ENST00000420670;Name=ENSE00001419415;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001419415;rank=3;version=1 +9 havana five_prime_UTR 57290 57352 . - . Parent=transcript:ENST00000420670 +9 havana exon 95122 95187 . - . Parent=transcript:ENST00000420670;Name=ENSE00001424804;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001424804;rank=2;version=1 +9 havana five_prime_UTR 95122 95187 . - . Parent=transcript:ENST00000420670 +9 havana exon 136609 136666 . - . Parent=transcript:ENST00000420670;Name=ENSE00001692264;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001692264;rank=1;version=1 +9 havana five_prime_UTR 136609 136666 . - . Parent=transcript:ENST00000420670 diff --git a/test/csq/ENST00000420670/start-stop-lost.txt b/test/csq/ENST00000420670/start-stop-lost.txt new file mode 100644 index 0000000..090f5aa --- /dev/null +++ b/test/csq/ENST00000420670/start-stop-lost.txt @@ -0,0 +1,3 @@ +44688 C T missense|SEMA4D|ENST00000420670|protein_coding|-|1M>1I|44688C>T +44688 C T missense|SEMA4D|ENST00000420670|protein_coding|-|1M>1I|44688C>T + diff --git a/test/csq/ENST00000420670/start-stop-lost.vcf b/test/csq/ENST00000420670/start-stop-lost.vcf new file mode 100644 index 0000000..efc96fd --- /dev/null +++ b/test/csq/ENST00000420670/start-stop-lost.vcf @@ -0,0 +1,7 @@ +##fileformat=VCFv4.2 +##contig= +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO +9 44688 . C T . . EXP=missense|SEMA4D|ENST00000420670|protein_coding|-|1M>1I|44688C>T;type=ENST00000420670:92020369-C-T, this cannot be real, transcript has only one aa diff --git a/test/csq/ENST00000423372/ENST00000423372.fa b/test/csq/ENST00000423372/ENST00000423372.fa new file mode 100644 index 0000000..2bf06cf --- /dev/null +++ b/test/csq/ENST00000423372/ENST00000423372.fa @@ -0,0 +1,76 @@ +>1 1:134901-139379 +ACCTACCAAAACATTTACATAATGGTGGAAATATTCCAAAATTCAATATTTTGGGATTTA +TACACAAAAGATAAACAAATTAGAGGCCAAGAGGCTGCCGGAAGGGAAAAACAGGGCCTG +GAATGGCCGACGTGAGGAATGAGCTGGGCCTAAAGAGGCCACTGGCAGGCAGGAGCTGGA +CCTGCCGAAGTGGCCGAAAGGCAGGAGCTTTGGACTGGGGAGGCCGCAGTGAGGCGAGAG +CTAGCTGGGCGTGGAGAGTCCGCTGTGAGGCCGAGGCCGAGGCTGGGCCCGTGCAGGCCT +TCGAGACGCAGGAGGCCGGGCCTGCAAAGGCCGACTGGAGATCAAGTTCTGCGCCTGAAG +AGGCTGCCAAAAGTCAAAAGCGGGGCCTGGGAAGGCCGCCGAGAGCCATGAGCTGGGCTG +GGCCGAAAGAGGCCACTGGGAGGCAGGAGGAGCTGGGCCTGGAGAGGCTGACTCGAGGAA +GTTTTGCACCTGGAGAGGCCGTCGAGAGGACGGAGCTGGGCCCAGGGAGGCCGACTTGCT +GCTCTTCCAGGCCCACTTCCAGGCCGACTTGAGGACGACTTGGGCCTGCAGAGGCCGCCG +GGAGGCTGGAGCTAAGCCTGGAGAGACTGACTTCGGGACGATTTGGGCCTGCGGAGGCCG +CCGGGAGGCCCAAGCTGGGCCTAGAGGAGCCCACCGACCGGAGGCCATTTGGGGCCTGCA +GATGTCATCGGAGGGCCAGGAGCTGAGCCTGGAGAGGCCACCGCGAGGCCTGAGCTGGGC +CTGGGGAGCTTGGCTTAGGGAAGTTGTGGGCCTACCAGGGCCGCTGGGAGCTGGGCAGGA +GCTGAGTCCAAAGACGTTGTTGGGACCTGGAGTCGGGCCAGAGTCCGGCCTGGAGATGCA +GCCGGGAGGAAGAGCTGGGCCCGGAGGGGGCGCCGGGAGGCTGCAAGTGGGTCTGAGAGG +CCAACTTGAGGAGGCCTGGCCTCTGCCTCCCGCATTGCCCAGCTGTTCCTCCTGGCTGCA +TCTCCCACCTCCCAGCAAACAAGCTCTTTTGGCTCAGCTCCCGCCTGCGTTTGTAGACCC +CAAAGTTTCTGCAACCAAGCTCTTCAGACCCACATCCCTTCTCCCAGTGACTGAACAGTC +CCAGCTCCGGCTGGAGAAGGGTGTCTGCAGACCCCGCTGTTGCCTCCCAGGGGAGTCTCC +AGGCCCAGCTCTCGCCCCACCGCGACCTCCCAGGCCCAAGTCCCTGCCTACCTCCCAGCA +GCCCGAGTGCGATCCTGTTCCTCCCTCACGGTGGCCTGTTGAGGCAGGGGGTCACGCTGA +CCTCTGTCCGCGTGGGAGGGGCCGGTGTGAGGCAAGGGCTCACACTGACCTCTCTCAGCG +TGGGAGGGGCCGGTGTGAGGCAAGGGGCTCACGCTGACCTCTGTCCGCGTGGGAGGGGCC +GGTGTGAGGCAAGGGCTCACACTGACCTCTCTCAGCGTGGGAGGGGCCGGTGTGAGGCAA +GGGGCTCACGCTGACCTCTGTCCGCGTGGGAGGGGCTGGTGTGAGGCAAGGGCTCAGGCT +GACCTCTCTCAGCGTGGGAGGGGCCGGTGTGAGGCAAGGGGCTCACGCTGACCTCTGTCC +GCGTGGGAGGGGCCGGTGTGAGACAAGGGGCTCACACTGACCTCTCTCAGCGTGGGAGGG +GCCGGTGTGAGGCAAGGGGCTCAGGCTGACCTCTGTCCGCGTGGGAGGGGCCGGTGTGAG +GCAAGGGGCTCAGGCTGACCTCTGTCCGCGTGGGAGGGGCCGGTGTGAGGCAAGGGGCTC +AGGCTGACCTCTGTCCGCGTGGGAGGGGCCGGGGTGAGGCAAGGGCTCACACTGACCTCT +CTCAGCGTGGGAGGGGCCGGTGTGAGGCAAGGGGCTCGGGCTGACCTCTCTCAGCGTGGG +AGGGGCCGGTGTGAGGCAAGGGGCTCGGGCTGACCTCTCTCAGCGTGGGAGGGGCCGGTG +TGAGGCAAGGGGCTCGGGCTGACCTCTGTCCGCGTGGGAGGGGCCGGTGTGAGGCAAGGG +GCTCGGGCTGACCTCTCTCAGCGTGGGAGGGGCCGGTGTGAGGCAAGGGGCTCACGCTGA +CCTCTGTCCGCGTGGGAGGGGCCGGTGTGAGGCAAGGGCTCACACTGACCTCTCTCAGCG +TGGGAGGGGCCGGTGTGAGACAAGGGGCTCACGCTGACCTCTGTCCACGTGGGAGGGGCC +GGTGTGAGGCAAGGGGCTCACACTGACCTCTCTCAGCGTGGGAGGGGCCGGTGTGAGGCA +AGGGGCTCACGCTGACCTCTGTCCGCGTGGGAGGGGCCGGTGTGAGGCAAGGGCTCACAC +TGACCTCTCTCAGCGTGGGAGGAGCCAGTGTGAGGCAGGGGCTCACGCCTCTGGGCAGGG +TGCCAGAGGCATGAGTTGGGCATCAACAGGCCACCGTGAGGGAGGAGCTGGGCCGCACGC +GGGCTGCTGGGAGGCAGGCAGGGACTTGGCCCCGGGAGGCCGCCGTGGGGGCAAGAGCTG +GGCCTGGAGAGGCCCCTGGGAGGCAAGGGCGGGGCCTGCAGAGGCTGTTCTCCAACCAGT +GCTAGAACTGTACAGGCCACCAGGAGGCAGGAGGTGGGCCCTCAGAGCTTGGCTGGAGAA +AGTTCGGGGCCTACAAAGGCGGTTGGGAGCTGGGCAGGAGTTGAGCCAAAAGAGCTTGCT +TACTTGCTGGGAGGCAGGGCCGGGAGAGCCCGACTTCAGGACAACTTGGGCCTGCGGCGG +TCGCCGGGAGGCCCAACCTTGGCGTGGAGGAGCCCACCGACCGGAGACCATTTGGGGCCT +GGAGATGCCATCGGAGGGCAGGAGCTCATCCTGGAGAGGCCACCGTGAGGCCTGACCTGG +GCCTGGGGAGCTTGGCTTGAGGAAGCTGTGGACCGACCAAGGCCGCCAGGAGATGGGTAG +GCACTGAGTCCAAAGAGGTTGTTGAGAGGCAGGAATCGGGCCTGGAGACCCAACCAGGAA +GAAGAGCTGGGCCCGGAGAGAACGCCCGGAGGGTGCAAGTGGGTCTGGAGAGGCCGACTT +GAGGAGGTTCTGGGCCCGGAGAGGCCGCTGGAAGGGAAAAACTGGGCCTGGAAAGGCCGT +TGTCAGGAATGAGCCCCATGGGCCTGAAGAGGCCACTGGCAGGCGGGAGCTGGGCCTGCC +GAAGCGGCCGAGAGGCAGGAGCTTTGGACTCGGGAGGCCGCAGTGAAGCAACAGCTAGCT +GGGCGTGGAGAGTCCGCTGTGAGGCAGAGGCTGGGCCTGTGCAGGCCTTCGGGAGGCAGG +AGGCTGGGCCTTGTCGAGGCCTGCAGAGGCCACCGAAAGTCAAAAGCGGGGCTTGGGAAG +GCCGCCGGGAGGCATGAGCTGGGCTGGGCCGAAAGAGGCCACTGGGAGGCAGGAGGAGCT +GGGCCTGGAGAGGCTGCCGAAAGGCAGGAGCTTCACCTGAGGATGCCACAGTGAGACACC +ATCTGGGTCTGGAGGGTCCACTGTGAGGCAGAGGCTGACCTGTAGAGTCCGACAGTAGAC +AGAAGTTGGGCAAAAGCCTGATTTGAGGAAGTTTTGGGCTTCAAGAGTCAGCCACGAGGC +AGGCACTAGGCCTGGAAATGGCCTCACAGTCATAAGTTGGGCCTAAATGGGCCACTGTGA +GGGAGGAGCTGTGCCTGTTGAGGCTGCTGGCAGGCAGGCAGAAATTTGGCCTGGGGCAGC +TGCCATGAGGCAAGAGCTGGGCCTGGAAAAAGCCCCTGGGAGGCAAGAGCAGGGCCTGCA +GAGGCTGTTCTCAAGTCAAAGCTGGGCCTGTTGATGCCACCGGGAAGCAGAAGGTGGGCC +TGGAGAGTTTGACTTGAGGAAGTTTTGGGCCTACATTGGCCGCCATTAGCTGGACAGGAA +CTGGGCCAAAAAAGGCTGTTGTGAGGCAGCAGTTGTGCCTGTAGACCCAGCCAAGAGGAA +GAGGTGGGCCTGGAGAAGCCCCCATGAGGCAGAGGTTGGGCCTGTAGACGCTGACAGGAG +GCAGGAGCTGGGCCTGGACAGGTCAACTTGAGGAGATTTTGGGCCTTCATAGGCCACCAG +GAGGCAGCAGTTGGGACTAGAGAGTCTGACTTGAGTAAGTTTTGGGCCCGGAGATGATGT +CCTGGGACAGGAGTTGGCCGTGGAGAGGCCACCGTGAGGCATAAGCTGGATGTAGAGAGG +CCAGTGTGAGGCAAGACCTGGGCCTGTCTAGGCTGCTGGGAGACAGGCAGGAATCTGGCC +AGGGAAGGTTGCCATGAGACAAAAGTTGGGCCTGGAAAGGCCCTTGTGAAGCATGAGCTT +GGCCTAAAGAGGCCACTGGGTGGCAGGAGCTGGGTGTGTAGAAGCTGCTGAAAGGTTGGG +AGCTTGGCTTGGGGGGTCCACAGTGAGGTAGAAGCTGGGCGTGAAGAATCTGCTGTGAGG +CAGACGTTGGGACTGTAGAGGCTGACGGGAGGCAGAGGC diff --git a/test/csq/ENST00000423372/ENST00000423372.fa.fai b/test/csq/ENST00000423372/ENST00000423372.fa.fai new file mode 100644 index 0000000..a21d1c0 --- /dev/null +++ b/test/csq/ENST00000423372/ENST00000423372.fa.fai @@ -0,0 +1 @@ +1 4479 19 60 61 diff --git a/test/csq/ENST00000423372/ENST00000423372.gff b/test/csq/ENST00000423372/ENST00000423372.gff new file mode 100644 index 0000000..711c89a --- /dev/null +++ b/test/csq/ENST00000423372/ENST00000423372.gff @@ -0,0 +1,8 @@ +1 ensembl gene 1 4479 . - . ID=gene:ENSG00000237683;Name=AL627309.1;biotype=protein_coding;description=Uncharacterized protein [Source:UniProtKB/TrEMBL%3BAcc:R4GN28];gene_id=ENSG00000237683;logic_name=ensembl;version=5 +1 ensembl transcript 1 4479 . - . ID=transcript:ENST00000423372;Parent=gene:ENSG00000237683;Name=AL627309.1-201;biotype=protein_coding;tag=basic;transcript_id=ENST00000423372;version=3 +1 ensembl exon 1 902 . - . Parent=transcript:ENST00000423372;Name=ENSE00002314092;constitutive=1;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00002314092;rank=2;version=1 +1 ensembl three_prime_UTR 1 902 . - . Parent=transcript:ENST00000423372 +1 ensembl three_prime_UTR 2721 3629 . - . Parent=transcript:ENST00000423372 +1 ensembl exon 2721 4479 . - . Parent=transcript:ENST00000423372;Name=ENSE00002221580;constitutive=1;ensembl_end_phase=-1;ensembl_phase=0;exon_id=ENSE00002221580;rank=1;version=1 +1 ensembl CDS 3630 4409 . - 0 ID=CDS:ENSP00000473460;Parent=transcript:ENST00000423372;protein_id=ENSP00000473460 +1 ensembl five_prime_UTR 4410 4479 . - . Parent=transcript:ENST00000423372 diff --git a/test/csq/ENST00000423372/insert3.txt b/test/csq/ENST00000423372/insert3.txt new file mode 100644 index 0000000..cc5ea73 --- /dev/null +++ b/test/csq/ENST00000423372/insert3.txt @@ -0,0 +1,6 @@ +2723 G GAAA splice_region&3_prime_utr|AL627309.1|ENST00000423372|protein_coding +2723 G GAAA splice_region&3_prime_utr|AL627309.1|ENST00000423372|protein_coding + +3630 T TAAA stop_lost&inframe_insertion|AL627309.1|ENST00000423372|protein_coding|-|260*>260CL|3630T>TAAA +3630 T TAAA stop_lost&inframe_insertion|AL627309.1|ENST00000423372|protein_coding|-|260*>260CL|3630T>TAAA + diff --git a/test/csq/ENST00000423372/insert3.txt-l b/test/csq/ENST00000423372/insert3.txt-l new file mode 100644 index 0000000..cc5ea73 --- /dev/null +++ b/test/csq/ENST00000423372/insert3.txt-l @@ -0,0 +1,6 @@ +2723 G GAAA splice_region&3_prime_utr|AL627309.1|ENST00000423372|protein_coding +2723 G GAAA splice_region&3_prime_utr|AL627309.1|ENST00000423372|protein_coding + +3630 T TAAA stop_lost&inframe_insertion|AL627309.1|ENST00000423372|protein_coding|-|260*>260CL|3630T>TAAA +3630 T TAAA stop_lost&inframe_insertion|AL627309.1|ENST00000423372|protein_coding|-|260*>260CL|3630T>TAAA + diff --git a/test/csq/ENST00000423372/insert3.vcf b/test/csq/ENST00000423372/insert3.vcf new file mode 100644 index 0000000..cfeba43 --- /dev/null +++ b/test/csq/ENST00000423372/insert3.vcf @@ -0,0 +1,7 @@ +##fileformat=VCFv4.2 +##contig= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO +1 2723 . G GAAA . . EXP=splice_region&3_prime_utr|AL627309.1|ENST00000423372|protein_coding;type=three_prime_UTR:2,exon:2, spliced utr +1 3630 . T TAAA . . EXP=stop_lost&inframe_insertion|AL627309.1|ENST00000423372|protein_coding|-|260*>260CL|3630T>TAAA;type=CDS:0, another stop 2aa further diff --git a/test/csq/ENST00000423372/snps.txt b/test/csq/ENST00000423372/snps.txt new file mode 100644 index 0000000..15d636e --- /dev/null +++ b/test/csq/ENST00000423372/snps.txt @@ -0,0 +1,117 @@ +1 A C 3_prime_utr|AL627309.1|ENST00000423372|protein_coding +1 A C 3_prime_utr|AL627309.1|ENST00000423372|protein_coding + +3 C A 3_prime_utr|AL627309.1|ENST00000423372|protein_coding +3 C A 3_prime_utr|AL627309.1|ENST00000423372|protein_coding + +4 T A 3_prime_utr|AL627309.1|ENST00000423372|protein_coding +4 T A 3_prime_utr|AL627309.1|ENST00000423372|protein_coding + +5 A C 3_prime_utr|AL627309.1|ENST00000423372|protein_coding +5 A C 3_prime_utr|AL627309.1|ENST00000423372|protein_coding + +9 A C 3_prime_utr|AL627309.1|ENST00000423372|protein_coding +9 A C 3_prime_utr|AL627309.1|ENST00000423372|protein_coding + +10 A C 3_prime_utr|AL627309.1|ENST00000423372|protein_coding +10 A C 3_prime_utr|AL627309.1|ENST00000423372|protein_coding + +2712 A C intron|AL627309.1||protein_coding +2712 A C intron|AL627309.1||protein_coding + +2713 G A splice_region|AL627309.1|ENST00000423372|protein_coding +2713 G A splice_region|AL627309.1|ENST00000423372|protein_coding + +2717 G A splice_region|AL627309.1|ENST00000423372|protein_coding +2717 G A splice_region|AL627309.1|ENST00000423372|protein_coding + +2718 G A splice_region|AL627309.1|ENST00000423372|protein_coding +2718 G A splice_region|AL627309.1|ENST00000423372|protein_coding + +2719 G A splice_donor|AL627309.1|ENST00000423372|protein_coding +2719 G A splice_donor|AL627309.1|ENST00000423372|protein_coding + +2721 C A splice_region&3_prime_utr|AL627309.1|ENST00000423372|protein_coding +2721 C A splice_region&3_prime_utr|AL627309.1|ENST00000423372|protein_coding + +2723 G A splice_region&3_prime_utr|AL627309.1|ENST00000423372|protein_coding +2723 G A splice_region&3_prime_utr|AL627309.1|ENST00000423372|protein_coding + +2724 G A 3_prime_utr|AL627309.1|ENST00000423372|protein_coding +2724 G A 3_prime_utr|AL627309.1|ENST00000423372|protein_coding + +2725 A C 3_prime_utr|AL627309.1|ENST00000423372|protein_coding +2725 A C 3_prime_utr|AL627309.1|ENST00000423372|protein_coding + +2729 C A 3_prime_utr|AL627309.1|ENST00000423372|protein_coding +2729 C A 3_prime_utr|AL627309.1|ENST00000423372|protein_coding + +2730 C A 3_prime_utr|AL627309.1|ENST00000423372|protein_coding +2730 C A 3_prime_utr|AL627309.1|ENST00000423372|protein_coding + +3621 G A 3_prime_utr|AL627309.1|ENST00000423372|protein_coding +3621 G A 3_prime_utr|AL627309.1|ENST00000423372|protein_coding + +3622 C A 3_prime_utr|AL627309.1|ENST00000423372|protein_coding +3622 C A 3_prime_utr|AL627309.1|ENST00000423372|protein_coding + +3626 A C 3_prime_utr|AL627309.1|ENST00000423372|protein_coding +3626 A C 3_prime_utr|AL627309.1|ENST00000423372|protein_coding + +3627 C A 3_prime_utr|AL627309.1|ENST00000423372|protein_coding +3627 C A 3_prime_utr|AL627309.1|ENST00000423372|protein_coding + +3628 A C 3_prime_utr|AL627309.1|ENST00000423372|protein_coding +3628 A C 3_prime_utr|AL627309.1|ENST00000423372|protein_coding + +3630 T A @3632 +3630 T A @3632 + +3632 A C stop_lost|AL627309.1|ENST00000423372|protein_coding|-|260*>260G|3630T>A+3632A>C +3632 A C stop_lost|AL627309.1|ENST00000423372|protein_coding|-|260*>260G|3630T>A+3632A>C + +3633 T A @3634 +3633 T A @3634 + +3634 A C missense|AL627309.1|ENST00000423372|protein_coding|-|259L>259C|3633T>A+3634A>C +3634 A C missense|AL627309.1|ENST00000423372|protein_coding|-|259L>259C|3633T>A+3634A>C + +3638 T A missense|AL627309.1|ENST00000423372|protein_coding|-|258N>258Y|3638T>A +3638 T A missense|AL627309.1|ENST00000423372|protein_coding|-|258N>258Y|3638T>A + +3639 G A synonymous|AL627309.1|ENST00000423372|protein_coding|-|257P|3639G>A +3639 G A synonymous|AL627309.1|ENST00000423372|protein_coding|-|257P|3639G>A + +4401 C A @4402 +4401 C A @4402 + +4402 A C missense|AL627309.1|ENST00000423372|protein_coding|-|3L>3R|4401C>A+4402A>C +4402 A C missense|AL627309.1|ENST00000423372|protein_coding|-|3L>3R|4401C>A+4402A>C + +4406 A C missense|AL627309.1|ENST00000423372|protein_coding|-|2S>2A|4406A>C +4406 A C missense|AL627309.1|ENST00000423372|protein_coding|-|2S>2A|4406A>C + +4407 G A @4408 +4407 G A @4408 + +4408 G A missense|AL627309.1|ENST00000423372|protein_coding|-|1T>1I|4407G>A+4408G>A +4408 G A missense|AL627309.1|ENST00000423372|protein_coding|-|1T>1I|4407G>A+4408G>A + +4410 A C 5_prime_utr|AL627309.1|ENST00000423372|protein_coding +4410 A C 5_prime_utr|AL627309.1|ENST00000423372|protein_coding + +4412 A C 5_prime_utr|AL627309.1|ENST00000423372|protein_coding +4412 A C 5_prime_utr|AL627309.1|ENST00000423372|protein_coding + +4413 A C 5_prime_utr|AL627309.1|ENST00000423372|protein_coding +4413 A C 5_prime_utr|AL627309.1|ENST00000423372|protein_coding + +4414 G A 5_prime_utr|AL627309.1|ENST00000423372|protein_coding +4414 G A 5_prime_utr|AL627309.1|ENST00000423372|protein_coding + +4418 G A 5_prime_utr|AL627309.1|ENST00000423372|protein_coding +4418 G A 5_prime_utr|AL627309.1|ENST00000423372|protein_coding + +4419 G A 5_prime_utr|AL627309.1|ENST00000423372|protein_coding +4419 G A 5_prime_utr|AL627309.1|ENST00000423372|protein_coding + diff --git a/test/csq/ENST00000423372/snps.txt-l b/test/csq/ENST00000423372/snps.txt-l new file mode 100644 index 0000000..fac7f82 --- /dev/null +++ b/test/csq/ENST00000423372/snps.txt-l @@ -0,0 +1,117 @@ +1 A C 3_prime_utr|AL627309.1|ENST00000423372|protein_coding +1 A C 3_prime_utr|AL627309.1|ENST00000423372|protein_coding + +3 C A 3_prime_utr|AL627309.1|ENST00000423372|protein_coding +3 C A 3_prime_utr|AL627309.1|ENST00000423372|protein_coding + +4 T A 3_prime_utr|AL627309.1|ENST00000423372|protein_coding +4 T A 3_prime_utr|AL627309.1|ENST00000423372|protein_coding + +5 A C 3_prime_utr|AL627309.1|ENST00000423372|protein_coding +5 A C 3_prime_utr|AL627309.1|ENST00000423372|protein_coding + +9 A C 3_prime_utr|AL627309.1|ENST00000423372|protein_coding +9 A C 3_prime_utr|AL627309.1|ENST00000423372|protein_coding + +10 A C 3_prime_utr|AL627309.1|ENST00000423372|protein_coding +10 A C 3_prime_utr|AL627309.1|ENST00000423372|protein_coding + +2712 A C intron|AL627309.1||protein_coding +2712 A C intron|AL627309.1||protein_coding + +2713 G A splice_region|AL627309.1|ENST00000423372|protein_coding +2713 G A splice_region|AL627309.1|ENST00000423372|protein_coding + +2717 G A splice_region|AL627309.1|ENST00000423372|protein_coding +2717 G A splice_region|AL627309.1|ENST00000423372|protein_coding + +2718 G A splice_region|AL627309.1|ENST00000423372|protein_coding +2718 G A splice_region|AL627309.1|ENST00000423372|protein_coding + +2719 G A splice_donor|AL627309.1|ENST00000423372|protein_coding +2719 G A splice_donor|AL627309.1|ENST00000423372|protein_coding + +2721 C A splice_region&3_prime_utr|AL627309.1|ENST00000423372|protein_coding +2721 C A splice_region&3_prime_utr|AL627309.1|ENST00000423372|protein_coding + +2723 G A splice_region&3_prime_utr|AL627309.1|ENST00000423372|protein_coding +2723 G A splice_region&3_prime_utr|AL627309.1|ENST00000423372|protein_coding + +2724 G A 3_prime_utr|AL627309.1|ENST00000423372|protein_coding +2724 G A 3_prime_utr|AL627309.1|ENST00000423372|protein_coding + +2725 A C 3_prime_utr|AL627309.1|ENST00000423372|protein_coding +2725 A C 3_prime_utr|AL627309.1|ENST00000423372|protein_coding + +2729 C A 3_prime_utr|AL627309.1|ENST00000423372|protein_coding +2729 C A 3_prime_utr|AL627309.1|ENST00000423372|protein_coding + +2730 C A 3_prime_utr|AL627309.1|ENST00000423372|protein_coding +2730 C A 3_prime_utr|AL627309.1|ENST00000423372|protein_coding + +3621 G A 3_prime_utr|AL627309.1|ENST00000423372|protein_coding +3621 G A 3_prime_utr|AL627309.1|ENST00000423372|protein_coding + +3622 C A 3_prime_utr|AL627309.1|ENST00000423372|protein_coding +3622 C A 3_prime_utr|AL627309.1|ENST00000423372|protein_coding + +3626 A C 3_prime_utr|AL627309.1|ENST00000423372|protein_coding +3626 A C 3_prime_utr|AL627309.1|ENST00000423372|protein_coding + +3627 C A 3_prime_utr|AL627309.1|ENST00000423372|protein_coding +3627 C A 3_prime_utr|AL627309.1|ENST00000423372|protein_coding + +3628 A C 3_prime_utr|AL627309.1|ENST00000423372|protein_coding +3628 A C 3_prime_utr|AL627309.1|ENST00000423372|protein_coding + +3630 T A @3632 +3630 T A stop_lost|AL627309.1|ENST00000423372|protein_coding|-|260*>260C|3630T>A + +3632 A C stop_lost|AL627309.1|ENST00000423372|protein_coding|-|260*>260G|3630T>A+3632A>C +3632 A C stop_lost|AL627309.1|ENST00000423372|protein_coding|-|260*>260G|3632A>C + +3633 T A @3634 +3633 T A missense|AL627309.1|ENST00000423372|protein_coding|-|259L>259F|3633T>A + +3634 A C missense|AL627309.1|ENST00000423372|protein_coding|-|259L>259C|3633T>A+3634A>C +3634 A C stop_gained|AL627309.1|ENST00000423372|protein_coding|-|259L>259*|3634A>C + +3638 T A missense|AL627309.1|ENST00000423372|protein_coding|-|258N>258Y|3638T>A +3638 T A missense|AL627309.1|ENST00000423372|protein_coding|-|258N>258Y|3638T>A + +3639 G A synonymous|AL627309.1|ENST00000423372|protein_coding|-|257P|3639G>A +3639 G A synonymous|AL627309.1|ENST00000423372|protein_coding|-|257P|3639G>A + +4401 C A @4402 +4401 C A synonymous|AL627309.1|ENST00000423372|protein_coding|-|3L|4401C>A + +4402 A C missense|AL627309.1|ENST00000423372|protein_coding|-|3L>3R|4401C>A+4402A>C +4402 A C missense|AL627309.1|ENST00000423372|protein_coding|-|3L>3R|4402A>C + +4406 A C missense|AL627309.1|ENST00000423372|protein_coding|-|2S>2A|4406A>C +4406 A C missense|AL627309.1|ENST00000423372|protein_coding|-|2S>2A|4406A>C + +4407 G A @4408 +4407 G A synonymous|AL627309.1|ENST00000423372|protein_coding|-|1T|4407G>A + +4408 G A missense|AL627309.1|ENST00000423372|protein_coding|-|1T>1I|4407G>A+4408G>A +4408 G A missense|AL627309.1|ENST00000423372|protein_coding|-|1T>1I|4408G>A + +4410 A C 5_prime_utr|AL627309.1|ENST00000423372|protein_coding +4410 A C 5_prime_utr|AL627309.1|ENST00000423372|protein_coding + +4412 A C 5_prime_utr|AL627309.1|ENST00000423372|protein_coding +4412 A C 5_prime_utr|AL627309.1|ENST00000423372|protein_coding + +4413 A C 5_prime_utr|AL627309.1|ENST00000423372|protein_coding +4413 A C 5_prime_utr|AL627309.1|ENST00000423372|protein_coding + +4414 G A 5_prime_utr|AL627309.1|ENST00000423372|protein_coding +4414 G A 5_prime_utr|AL627309.1|ENST00000423372|protein_coding + +4418 G A 5_prime_utr|AL627309.1|ENST00000423372|protein_coding +4418 G A 5_prime_utr|AL627309.1|ENST00000423372|protein_coding + +4419 G A 5_prime_utr|AL627309.1|ENST00000423372|protein_coding +4419 G A 5_prime_utr|AL627309.1|ENST00000423372|protein_coding + diff --git a/test/csq/ENST00000423372/snps.vcf b/test/csq/ENST00000423372/snps.vcf new file mode 100644 index 0000000..a892792 --- /dev/null +++ b/test/csq/ENST00000423372/snps.vcf @@ -0,0 +1,45 @@ +##fileformat=VCFv4.2 +##contig= +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO +1 1 . A C . . EXP=3_prime_utr|AL627309.1|ENST00000423372|protein_coding;type=gene:0,transcript:0,exon:0,three_prime_UTR:0 +1 3 . C A . . EXP=3_prime_utr|AL627309.1|ENST00000423372|protein_coding;type=gene:2,transcript:2,exon:2,three_prime_UTR:2 +1 4 . T A . . EXP=3_prime_utr|AL627309.1|ENST00000423372|protein_coding;type=gene:3,transcript:3,exon:3,three_prime_UTR:3 +1 5 . A C . . EXP=3_prime_utr|AL627309.1|ENST00000423372|protein_coding;type=gene:4,transcript:4,exon:4,three_prime_UTR:4 +1 9 . A C . . EXP=3_prime_utr|AL627309.1|ENST00000423372|protein_coding;type=gene:8,transcript:8,exon:8,three_prime_UTR:8 +1 10 . A C . . EXP=3_prime_utr|AL627309.1|ENST00000423372|protein_coding;type=gene:9,transcript:9,exon:9,three_prime_UTR:9 +1 2712 . A C . . EXP=intron|AL627309.1||protein_coding;type=three_prime_UTR:-9,exon:-9 +1 2713 . G A . . EXP=splice_region|AL627309.1|ENST00000423372|protein_coding;type=three_prime_UTR:-8,exon:-8 +1 2717 . G A . . EXP=splice_region|AL627309.1|ENST00000423372|protein_coding;type=three_prime_UTR:-4,exon:-4 +1 2718 . G A . . EXP=splice_region|AL627309.1|ENST00000423372|protein_coding;type=three_prime_UTR:-3,exon:-3 +1 2719 . G A . . EXP=splice_donor|AL627309.1|ENST00000423372|protein_coding;type=three_prime_UTR:-2,exon:-2 +1 2721 . C A . . EXP=splice_region&3_prime_utr|AL627309.1|ENST00000423372|protein_coding;type=three_prime_UTR:0,exon:0 +1 2723 . G A . . EXP=splice_region&3_prime_utr|AL627309.1|ENST00000423372|protein_coding;type=three_prime_UTR:2,exon:2 +1 2724 . G A . . EXP=3_prime_utr|AL627309.1|ENST00000423372|protein_coding;type=three_prime_UTR:3,exon:3 +1 2725 . A C . . EXP=3_prime_utr|AL627309.1|ENST00000423372|protein_coding;type=three_prime_UTR:4,exon:4 +1 2729 . C A . . EXP=3_prime_utr|AL627309.1|ENST00000423372|protein_coding;type=three_prime_UTR:8,exon:8 +1 2730 . C A . . EXP=3_prime_utr|AL627309.1|ENST00000423372|protein_coding;type=three_prime_UTR:9,exon:9 +1 3621 . G A . . EXP=3_prime_utr|AL627309.1|ENST00000423372|protein_coding;type=CDS:-9 +1 3622 . C A . . EXP=3_prime_utr|AL627309.1|ENST00000423372|protein_coding;type=CDS:-8 +1 3626 . A C . . EXP=3_prime_utr|AL627309.1|ENST00000423372|protein_coding;type=CDS:-4 +1 3627 . C A . . EXP=3_prime_utr|AL627309.1|ENST00000423372|protein_coding;type=CDS:-3 +1 3628 . A C . . EXP=3_prime_utr|AL627309.1|ENST00000423372|protein_coding;type=CDS:-2 +1 3630 . T A . . EXP=@3632;EXPL=stop_lost|AL627309.1|ENST00000423372|protein_coding|-|260*>260C|3630T>A;type=CDS:0 +1 3632 . A C . . EXP=stop_lost|AL627309.1|ENST00000423372|protein_coding|-|260*>260G|3630T>A+3632A>C;EXPL=stop_lost|AL627309.1|ENST00000423372|protein_coding|-|260*>260G|3632A>C;type=CDS:2 +1 3633 . T A . . EXP=@3634;EXPL=missense|AL627309.1|ENST00000423372|protein_coding|-|259L>259F|3633T>A;type=CDS:3 +1 3634 . A C . . EXP=missense|AL627309.1|ENST00000423372|protein_coding|-|259L>259C|3633T>A+3634A>C;EXPL=stop_gained|AL627309.1|ENST00000423372|protein_coding|-|259L>259*|3634A>C;type=CDS:4 +1 3638 . T A . . EXP=missense|AL627309.1|ENST00000423372|protein_coding|-|258N>258Y|3638T>A;type=CDS:8 +1 3639 . G A . . EXP=synonymous|AL627309.1|ENST00000423372|protein_coding|-|257P|3639G>A;type=CDS:9 +1 4401 . C A . . EXP=@4402;EXPL=synonymous|AL627309.1|ENST00000423372|protein_coding|-|3L|4401C>A;type=five_prime_UTR:-9 +1 4402 . A C . . EXP=missense|AL627309.1|ENST00000423372|protein_coding|-|3L>3R|4401C>A+4402A>C;EXPL=missense|AL627309.1|ENST00000423372|protein_coding|-|3L>3R|4402A>C;type=five_prime_UTR:-8 +1 4406 . A C . . EXP=missense|AL627309.1|ENST00000423372|protein_coding|-|2S>2A|4406A>C;type=five_prime_UTR:-4 +1 4407 . G A . . EXP=@4408;EXPL=synonymous|AL627309.1|ENST00000423372|protein_coding|-|1T|4407G>A;type=five_prime_UTR:-3 +1 4408 . G A . . EXP=missense|AL627309.1|ENST00000423372|protein_coding|-|1T>1I|4407G>A+4408G>A;EXPL=missense|AL627309.1|ENST00000423372|protein_coding|-|1T>1I|4408G>A;type=five_prime_UTR:-2-incomplete 5'cds,not a start +1 4410 . A C . . EXP=5_prime_utr|AL627309.1|ENST00000423372|protein_coding;type=five_prime_UTR:0 +1 4412 . A C . . EXP=5_prime_utr|AL627309.1|ENST00000423372|protein_coding;type=five_prime_UTR:2 +1 4413 . A C . . EXP=5_prime_utr|AL627309.1|ENST00000423372|protein_coding;type=five_prime_UTR:3 +1 4414 . G A . . EXP=5_prime_utr|AL627309.1|ENST00000423372|protein_coding;type=five_prime_UTR:4 +1 4418 . G A . . EXP=5_prime_utr|AL627309.1|ENST00000423372|protein_coding;type=five_prime_UTR:8 +1 4419 . G A . . EXP=5_prime_utr|AL627309.1|ENST00000423372|protein_coding;type=five_prime_UTR:9 diff --git a/test/csq/ENST00000436063/ENST00000436063.fa b/test/csq/ENST00000436063/ENST00000436063.fa new file mode 100644 index 0000000..f64f1ce --- /dev/null +++ b/test/csq/ENST00000436063/ENST00000436063.fa @@ -0,0 +1,204 @@ +>1 1:94333353-94345494 +TATTCCAGAAACAAAAGTAGTTTTTTTTTAAAATAAAAGAGAACAGACATAGATGCTTCC +CTAACTCCAACTATGAATGTTATTGTCAGTTCTGCTATTACTAGCTTTTGACTCCAAGCA +GTAAATATGAGATTTTGGACATAGGTATGGGCAGACTGCATGACTAAAACACCAAAAGCA +ATGGCAACAAAAGGCAAAATTGACAAGTGGGATCTAATTAAACTAAAGAGTTTCTGCACA +GCAAAAGAAACTATTATCAGAGTGCACAGGCAATCTACAGAATGGGAGAAAATTTCTGTA +ATCTATCCATCTGACAAAGGGCTAATATCCAGAATCTACAAAGAACTTAAACAAATTTAC +AAGAAAAAACCCCATCAAAAAGTGGGTGAAGGATATGAACAGACACTTCTCAAAAGAAGA +CATTTATGCAGCCAACAAACATGAAAAAACGCTCATTATCACTGCTCATTAGAGAAATGC +AAATCAAAACCACAATGAGATACCATCTCATTGCCAGTTAGAATGGCAATCATTAAAAAG +TCAGGAAACAACAGATGCTGGAGAGGATATGGAGAACTAGGAACACTTTTACACTGTTGG +TGGGAGTGTAAACTAGTTCAACCATTGTGGAAGACAGTGTGGTGATTCCGCAAGGATCTA +GGACCAGAAATACCATTTGACCCAGCAATCCCATTACTGGGTATATACCCAAAGGATTAT +AAATCATTCTACTATAAAGACACATACACAAGTATGTTTACTGTGGCACTGTTCACAATA +GAAAAGACTTGGAACCAACCCAAATGCCCATGAATGATAGACTGGATAAAGAAAATGTGG +CACATATACACCATGGAATACTATGTGGCCATAAAAAAGCATGAGTTCATGTCCTTTGCA +GGGACATGGCTGAAGCTGGAAATCATCTCAGCAAGAACAGAAAACTAACACAAGAACAGA +AAACCAAACACTGCATGTTCTTACTCGTAAGTGGGAGGTAAACAATGAGAACACATGGAC +ACAGGGAGGGGAACATCACACACTGGGGCCTGTTGTGGGTGGGGGACTAGGGGAGGGATA +GCACTAGGAGAAATACCTAATGTAGATAGGTTGATGGGTGCAGCAAACCACCATGGCACG +TGTATACCTATGTAACCTGCATGTTCTACACATGTACCCCAAAACTATTATTAAAAAAAA +AAAAGATTTCATATTTGCTGATATCTCAAGGAAGCAGTATGCTGGAAAAATAGAGGTAAA +GTGAATAGTAACATAAAGGAAGCTACAACTCACCAAGTATCAACAGAAATGACCAACACT +CCTTGGGTGCCAGAAACCAGCTTAGCCAGGGTGCATACTGTACCACTGGAGAAGAGGTAA +GCTGGGTTAACTTCGAAGAAACCCTGGCCAACTTAAATTATAGTTTAATCCTGTTTTACT +TGGACCACAACACTTAAATCTAGATAAAAACCAATTATTCCTCCCTGTTTCAGTTGCCAA +GCAAGGAAAACAGCTCCTCTGCCCAAGCTTTCTAGGTCATATTCTTCATATCTTTGTATC +CCAACTTTCTGGATCTGAATTTTATAGCTAACTATAGGGCATTGCCTCTCTACCATCTCC +CGTCCCCTACACAGACACACACACACATACACACATAAAACTACCTATTAATTACAATAA +TGTTTATATATCTTTGATCATTTTTTAAAGTTCTTTGAACATGTTAGCAAACTTTATACT +TCCTATCTTTTAATTAAATTTTCTTTAAATAACTAAGCATTGAAAACTTTACAAACCATC +AGTTATCTTAAAATGGTTGAGATTTTTTTTCCTTTTTTCCCATAAAGAGTCTACACCAGG +GTGGGTCTTTTAGACACCCCTATTTTCTAAGGGCATGTAATCGATTCTCAAATCAACTTT +TTCCAAATACAAATTCCTGTATGAACAGGGCCAGTCTATGGTAAATTAATTTAGATGATG +GTGTTAGTTTTCCAAACGTCTTTAATAAGTAAATAAAGGAGCAATGTAAAATGTTGCAGT +TTGCTTGGTAAATCTTAATTGCGAAATTTCTTCTTCTTTCGGAACTTTTTTCCTGCTGCA +TTTGCTGCTTTTTCAGCCATGATCTCTGAGTACTTCCTTCGGTTGTATCTGAAAAAGAAA +AATCAGAACTTTATGTTTGATATATCAGACATTAGAAGTTAATATAACCTTAGGGTAAAA +GTTGGGAATGGAGTGGTGGACAAGACAAGTATAGTCTCTGACCTCATAGCACTTGCTTGC +AATCTAGGGAGAAAAAATGGCAACTGTAGTAGGAAGACTTTCCTACTATATGCACTATAT +CCATCTATCTATCCATATATCCATATATGATCTATATATGCACTATATCCATCCACCAGG +CTGTATCAAATGCTTTAAACATTTTTGAGGGATAAAAACACAAAAATCAGGACTAAGCAA +AACAAAAAGTCACACTTATCCTGAAAATGCACAGTATGATATATATATTTCTTAGAAGCG +ACCAATGGTTTTCAAAGTGTGGTCTGTGGAGTAGACCCTTTCAAGGGATTCATTAGGTAA +AAACTATTTTCTCAAGAATACTAAGGCATTAATCGCTTTTTTCACCCTCGTTCTCTCATG +AGTGTAGTGTTTTCCAGGGGCTACGTGATGTATGTTATCTGCAGAAGCAGGTATGAGCCT +CTGTCTTTAGTTAAGCCAGACATTAAAGAGATTTGCACTAAATTATTTTTCATAAAAATA +TATATTCATGTTAATATGTTATGGGTTATTATAAATGAGTTATTTTTAAATTATTTGAAA +ATTTATAAGTTTATACATTTTTAAAGCAAAGTATACATATTATAAAATAAATATGAATTC +CTTTACCTTCTGAATTCAGAATCAGCCAGCAGTTCTTCCACAATAGTTCTTTTCCTTTGC +TTCTTGGGAATTCGTGAATGGTAGAAATCAGCTGGATTGTCAACAATGGTTCCAATCTGT +GAACAATTGATTGAAATAAGTCATGCATTGAGTGCCAAGATGCTTTCATACTTCAGTGTA +GCTCTAATTATATTTAGAGAAAGGAATGGAAAGAACAAGCTTACATTACACTAATAGTAA +TGTAAATTTTGCCATTTATTTAAAGCAAAAAAAAAAAAGTAGCATAGTGGTGCTATTATG +TTTCTTCAGTAGTTTATAGTAGATCCAAAATTTCTTTGCTAAACACTAAATTCATGATGC +ACAGTGTAACTAAAGGAGAAAAGTGGAACAGATAATATATACTTTTTGTTCTAGTTTCCC +AAATCAATGAATTAGACACATAAATTCTACTACATACCTATTTGGTTTCCTAGGTCATCA +CAAAGGCTGCCAGTTTGGCCTACTTAGTGATCATTCTGTATTTGTTCATACACTCAACTG +AATAAAATTTACAGTGATCACTATGCACCAGGCACTGTGTTACATGTTAGGGAAACAAAG +AACATCTGGTTCCTGCAGTGCAGAGCCTGCAGTCTTAAGGAAGCTCCACAAAAAGTAACT +AAAATATTAAAGCATAACATGTGCTGAACAAAACACTATAGACGCTCTGAAGACAAAGTG +ACCAATTGTACCTAAGAGAGGTAAGGAAGATTTAACAAAGAATGACAATTTAGCTTGAAT +TTGTATGGGTAAAATTTCACCAAACAAACAAGAACTATGGATATGCAAAGTCAAATTATG +CAGGGACTGGTATGTACGTGTTCTGACAAGACTGAGTAGCTAAGTGTGTTGGAATTTGTT +GGGCTATATGATGAAAGGCAGGTGAACTAGTTTGGGTATGGATTATTAATGGCTAAATGA +AAGGATACAGACCCAATCCTATGTCATAATTCATCACTGAATGTTTCTGAGCAGAGGTGT +AACACGAACAGATGAAAACATTTTAAAAACCAACTTGGATTAGTACACGTGATACCCTTT +TACCCCTATCCCGTATGGACTCTTGCTGTTAGGCTGATACTATTCATACATTCACATAGT +GAACTTTATAGGTTCAACAGGTTTTAGCTGACCTGGAAACCATTTGTAACACCATCTCTC +TAAATGTGATCAAATTAAAAGTTAGTGGCTGAATTGGGTAATGGCCATTCTTATATGGCC +TATGCAGATATGTTCCATACATTAGGCATGCACAATGGAAATATCCTCTATTTTAGGAGT +AAACTTTAAAGAACACTACAGTGCTTTCCAAACTAAAATTCACAGATCATCACCACTATT +CTGTTTGCTTCATACCTGGAAGTACTTGGGGAAGCCATCTCTATCATTTTTCTTGTAAAA +TCTTTTCGGGTCCATGCTGGCTCTCATCTTCAGTGCTTTGAGATCATTTTTCAGTTCATT +TGTCATTTCTGGAGCTTTCATACCAAACCAGCCATCCCCTGCTGTTTTTTGTCGTTCTTT +CTGAAATTATGATTTCAAAAATAAACATTCTAACAGCTAAGAGTATACATTATAATTCAT +TTCCCCTGAAGTAACACATACAGAAAATTTTGTAAATTAAAAACAAATGGTTACTTTATT +GAAAGCACTTAAATCCAGAATCATAGAGATAAAAGGAATTAAATCACAAAAAGTGACTTC +TCCGCTAAATTAGGGACAGGATTATCAGTTTCATAAATGAGGGCTCCGTAAAATCTATTT +TCTGTCTCAGAGAGTAACTGCTGACTTGCTGGGAGAATAACACACAACTTCAATTTTTAT +TGTCTAAAACAGACTATATGCAGTAAGAAAATGTATAAAAACACTTTCGTTTCTAGAGCT +TATATGTAAACATTTTTATTCAGTCACCCAGGAGTCTCAGAATGCCACTCATACAAGGAT +CCAGAACCTTGTGTTATTTCTACAATAAAACAAAATACTATTCTTTAGAAAACTCCTACA +AGTTATTTAATTTTGTTTCATTCATACAACAAGTATTTAGTTAGTGCCTACCATGTGCCA +GGGTGCTCCATATTACAGTAACATTACTAGAATACCATCCTCAACTTTCCTTCAAGCTCT +CTGGATAACTAGTCGAAATGGCAGATAGAAGTAATCTATATATATATATATTTTTTTAAA +AAACCTCTACTTATAGATGCACTATTGTGGCTGCAAAGATGTGAAAATCTATACATAATG +TGTTTATGGTACTATATTTTACAGCCCTTAGAAATCTGTAATTATTTTCTTTGGACTCAT +ATATAGACCAACAGATACAGTTTAATTGTGCAGTTATGTTGTATAAGCTGAAAATATATA +GCCAAACATATCTAAGCATTTTAATTAAGTCACTGTACTTACTCTGCGTTTTTTCTGAAG +TTGATACTTTGATTCACTATATGGTGGAACACAGTGGTTTTTTTCAAAATCAGGTGTAAT +GACGGCTTTCTGCAGAAGCTATAAAAACATAAAATTGGTTTTAAAATAATGTCAGAATGT +TATATAAGTTTTTCAACAGTTTAAACTTCTGTAAGTTTTAAAATTTTTAGTCAGCCTGGC +AAAGTGGCTCACACCTATAATCCTAGTGCTTTGAGGAGGCCAAGGGAGGAGGATCACTTG +AGGCCAGGAGTTTTAGACCACCTTGGTCAACATAGCAAGACCCTGACTGTAAAAAAAAAA +AAAAAAAGAAAAGAAATTAGTTGGGCATGGTGGCACACACCTGTAGTCCCAGCTACTCAG +GACGCTAAGGCAGAAGGATCACTTGAGGCCAGGAGCTTGAGGCTGCAGCAAGCTATGACT +GTGCCACTCACTCCAGCCTGGGTGACAGAGTGAGACCCTGTCTCCCCCCAAACCCAGCTC +CCTCCCAAAAAAAAAAAGAAAAAAGAAAAAAAAGGCCAGGCACGATGGCTCATGCCTATA +ATCCCAACTCTTTAGGAGGCCAAGGCAGGACAATCACTTGAGGCCAGGAGTTCAAGACTA +GCCTGGGTAACATAAGAAAACGCCATTTCTCCAAAATAAATAAATAAATTTGTGCAGTCA +AATCTGTTTATCTTTTCCTAAATGATTTCTGTACTTTTGTTACTTGACTAGGATGATTAT +ATTCTCCTAAAACTCTGTGTGACTAAAGGAACCTCAGGTTAATTAGTATTTTTCTCAGTA +CAAGAACCAAGTAAGACTGCTCTGTAGCCCTCAAAATAGTTTACAGGAATATAGTACAAG +CATTAATTTGGGACTGACATTTGAAATGATCAACTCAGAAATTAACAGTCAGGCACACAA +TTCAGGTTCAGGCCTAGATGTTTCTGTGTGGTATAGGTAGCCGTCTAGGCTTTCCTATCA +CTCATAAAAGGGGGCATGATATTTACTTAACAAATGATTAAGAGTTTGCTGTGAGTCAAG +TACTGTAGTACATTCAAGGACAGTGGTTCTCAACTGGGAGCATCTGGCAATGTCTGGAGA +CATTTTTGGTGGTGGTGAGGATAAGGAAGAATGCTACTGACATCTAGTGGGCAAAAGATA +GGGATGCTGTTAAACATCCTACTATGCACGGAACATCTCACAACAAAATTATGCAGCCCA +AAACATCAGTAGTGCTGAGACTGAAAAACCCTGTTTTAGGAATATAAAGAAAAGATGGTA +AGTTAATATATCACATGATCAACAATGAATCAGATCTATGCTAGATGTTATGGAAACAGA +GGGGTTGTGAGAAGGACTGGAGGTAAAATATTCCCCAAGGGCAACGATCAATTATTTTGC +ACTTGCTTGGGGAAAAGCAGGGTAAGTTCAGGCAACTACAGTAGTCTTCAGTGGCAAGAA +TAGAGCAGATGACAGCTGGGTGGGGTAGAGAGGTACTTTGAAGGATTCAAGAGAATACTG +TCACATCTGTGTGTGTGGTGTGTTTTTTGGGGCAGGGAGGAGAGATGTGGTCTAGCTATG +TTGCCCAGGTTGGTCTCAAACTCCTGGGCTTAAACAATTCTCCTGCCTCAGCCTCCCAAA +GTGCTGGGATTATAGATGTGAGCTACCTTGCCCAGCCGGATTTGTGTTTTTAGACAGAGA +AATCTAGAAGTGTGGAGGATGGCTTGAAGAACAAGATGAAAACAAGATCAATAAGGAAGC +CACTGGAGTAGTCCAGATGAGAAGCAAAGGCCTGCACTAGCTGGTGACAGTCGCTTGAAA +AGGAGGAAGCAGAGAAATATCTTCCCCTAGAGGCTTGGTGACTGACTACAAAAGGAAAAG +AGAGTTTGGTTTCATTAGCCAGAAAAAAGAATACAAGAAGAGGATTCCTGGTTCAGGCAG +GGAAAGGGGAATTAGTGACGTCAAGTACCTGAGGACATCTAAATGAACAAATAGGTACTT +GGATTTAAAGGTCTGAAAGTGACAGTGAGAAGCATCAAGGCTAGAAAATATAGATTTAGG +AGAAAACAGTGCAAGGTGTTGGCTAAAGCTAAGGGTTTGGGTAAAGTTACCTTAACAGTA +ATTCCTTCTGAAATTATATGTAAAATGTCTATATGCACATGTGCATTTTTTTCCGGGTGG +AAGAGGCAGGCAGGCATTCACAGCTTTCAGATTCTCAACAGTCTACACTAGTTAAGAACT +TAAGAACTAAAAGTATAGCAAGAAAAGGGAAAAAAACAAAACCCCTGGGATCATAATTGG +TGGGTGTAAGATGAGGAACACTGACCCTGTATTGATTTATTTTTAAAGCATTATCATTCA +TAGATAGGATTTTATTGTAAAAAGAAATGACTGTTTTAGAGAGAAGGAAAAAACTAACAC +ATTAGGCCAATGTGGTTTCACTGTAGGAAAATTAAGTCTTTTACCAAGGACTAATTTCTA +AAAGTGATTGGTTAGTTCTGTGAAAACCTAACAGCACAATTAACTTACCTCATTTTTCTT +TTTCTCCTTGATCTGTGTTAGGGTTCTCTTGTTAGACTGTAGTTTATCTGCATTAAAATT +AATATACAAACCACCCAACTGCTTGATACTCAGACCAGGGTCTATGCTGCTGCTTGTCAA +CTTCAGACTGAAAAAGAAATCATCACTTAAAGATCAAGTAATTAAATCAAAATGGAAACA +TATAAGATGGCATTTTAAAAAATCACTTATTCTTCTCTTCCCTTGTATTGTCCACAATAA +AGAAAAAAAAGCATCTTATTTTTATGAGGAATTCCTGAAAAAAAACTCTAAATAAATATA +TTTTTCATCATTTTATTTTATTTTTTGAGACAGGGTCTCACTGTTGGCCCAGGATGGAGT +GCAGTAGTGACCACTGCAGCCTTGAACTCTTGGGACTCAAGTGATCCTCCTACCTCAACC +TCCCTGGGTGGCTGGGACTACAGGTGCACACCCAACACCTGGCTCCATAATGTCAAATGA +ATGAGCCATTCCATGAAGAACCCAAGGCAGTGATTTTCTCATTCCCCAGGCTAACATTTC +ATATTTTTATGGTAAATTAACCACTTGAAATACATGTATCAAAAACTTATAAAAATAAAG +GAAAAACTTACAGTTTAGCCTTTGTGCTATTTAGGAAGTCTTCTTCATCACTAAACTCAT +CTTCATTTTCGTCATGGTCTGATGAATCTTCTTCACTTTTTTCATCCTCTTCCTCTTCTT +TTTCTTCCTCAATGGCAACCTCACTTGCCTTGTCTTCCTCTTCCAAGTAAAAATTTTTAT +CAGCACTCATTCCAGGAGTTGTGTCAATTACAAACAATGCATTGTCACATGACAGACTTC +CTGTGTCTCCACTTAATGACTCCCTTTGGCCACTATTTTCAACAAAACATAAAGTATCCT +CTTCATTCTCACTGTTTTCAGACTGTTGGCTTTCATCACTGCTGAGAACTAGTAAGACAG +AATTATCTTTACCCTGAGATGTGTTGGGCGCAGACGTGTATAGTTTGGTATCACATTCAA +AATCTACATTCCCTTCACTGTTCATGTCTTCACTGACACTTATAACTGTGGACTCTTCTT +CATCATCACTACCACCACAATCACCAAACTTTGTCAAGTCACTTGCTTTTATGGGGCTCT +TTTTGTTGTTATTCCATCTGCCTACTTCCACAGTTGCAAATGTTTGAGTTAATGATTTCA +TTACAGCCTCAGAGTTCAGATTAGAGTGCACTGATACAGCATTTTTATTTTGGGGGGTTG +AATGTCTCTGAGAAACTAACTGTTGAAGGCTAGTGTCCTGAAGTTCAGAAAGATTCTTCA +GCTGAGAACTTTTCTCATTAATTTCTTTCCCCTCATCTGTTATTCCATTGGCATCTTCAT +CCAAATCCTTACAATTCTGTTTTGTTTCTTTAAGAGATTCAACATTGGCCTGTTCGTGCA +CTGTTAATATATTTTCTGAACTTCTGTGGGAGAAATCATCATCAAAGTCATTATTATAGA +AATTTGGCTTATTTATCTCAGAAAGAGATCTTGCTTGTAAATGGGAAGTTTGTCTGGTAT +CTGAATCCTCTGAATTCACAGGTGTACCCACGATCTGTTTCTCATTTCCTGGTACAATCT +TACTATCTTTCTTTTCAGTTTGTGCCTTTAATTTCCTCTGCATACTCCTGGTTCTTCTAG +TTGCAATTCCAGAGAATGAAATGTCTGAGCTTGATGTCTCAGCATCAGATATAGCTTCTG +TATGAGATTCTTGGCTTGGATCTGTCAGAGATTTAGCCTTACTTCTTCTGGCTCCTGTAG +TTTTTTCTGTAGGAAGCACAATTCTAGAAATACCTGAAACATGAGATTCTGCTTCAGACA +CTATTTCTTCAGTGTAAGACTCCTTTGTTGGAGTTACTTTCGGCTTTTTCCTAACACTGG +ACACTGGGGAGCATGCAATTAAGATCTGCCTTCTCCTAGTTACCCTTAAAATGGTATCAT +GGTGCTCAGACACAGAATAATTTGACTCTGCCTCAGAGGTTTCTCCATCCGTAGATGGTT +CAGTCCCCTTTGGTAGTGAGCCTGTAGTTCTGCTCTTCCTCTTTCTAGCTTTAGGAGTTC +TAGGGATTAAACTTTGCTTCCCAGTGGTCTGTGATTCAGCAGTAGTTCGGGCATCAGATC +CAGTACTACTTTCTGGATGCGCTTGAATCCCATTAGCAGCAAAACTCTGCAAACCAGAGA +AAACACACTGTAATTTAGGTAGGGCTGGAACAAGGGCAAAGCAAATGAAATACTGACCCC +AAAAGCTAAAACCCAGTAAACAAGATTACCTTTAAAACAAAAAACAAAAAAACCTGCCCA +ACTCATGATTTTTAAAAAATCAAAATTTGGCCGGGCGCGGTGGCTTACGGCTGTAATCCC +AGCACTCTGGGAGGCCGAGGCAGGTGGATCACGAGGTCAGGAGTTCGAGACAGCTTGGCC +AACATAGTGAAACCCCATCTCTACTCAAAGTAAAAAAATTAGCGGGGCGTGTTGGTGCGC +ACCTGTAATCCCAACTACTCAGGAGCCTGAGGCAGAAGAATTGTTGGAATCCGGGAGGCA +GAAGTTGCAGTGAGCCGAGGCTGCGCCACTGCACTCTAGCCTGGGCGACAGAGCAAGACT +CCGAATCAAAAACAAACAAACAAAAAAATCAAAATTTAAACACTGGAGCCAACCCTGCAT +TTACTTCACTAGCCTCATCCTTCCTAGATGTAACTTCAGAAGCAGAACGATTAAAATTTT +TCTGTTTAAAGTCAAATATAATGGGTAGACCAACATTCTGACCCACCTATAGAAGAGGGG +AGAAAGGGAATATTAACTCTGAACACCGATGTGTTTAGGAACACACTGATGGAATCAGTC +GCCGCCCTTACCTTTACGTACAGGAAAAAATCGCCGCCGCTCCGTTCCCTGCATCGCTGA +GTCAGAATGAGACAGCCGACTAACGCCACTAAGAGTCACCAGGCGACGACACCACAGCCC +TCCTCACGCCTTAAGGAGGTGATGCTGGACAGCTGCCAGCCTCCCCACGTGAAAACGAAG +CTTTTTTTCCAGCCCCCCTAAATGGGGCTTGTGCATGGTGGCCGAAATTAACCCTCCTTG +GTACCGTGTTAACAGTAAGGTTTAAAAGTTCGAACTGTGCTTCTGCATTAAGGAGTTGAA +CGACCCAAATAAAGTTATCTAACCTCTCTTCCATACTAAAAATTGCCTTAAGAGACAGTG +GTGAAGGCTAAACAGTTTCCGTGACAGGCTTAGCACGGGGCCTGGGAGACCCAAGCGCGC +GGCAAGCTCGGGTCCTCTCTGTCGGCAGGTCCTCACCCTTAACCGGACCCTTGCGCCGCC +CCGCCTGCCTGAGCGCGGCTCTGCGAAGCGGCGAGAAGTAGGGAAGACTGGATTTCCTAC +CTTTTGCCCGGAACTTTCAGCCGACGCGGCTTGGATGCTGGCCTTAGCCCGTGCAGATCT +GGTAACCACCATCTTTCCGGCTCCCTCGCGACCACCACGACTTCCCTCTTCCCTGGCGCT +CCGGAAATGCGTCAGAGAACTGCCTCGAGCGCGTTTTCCGCGCAGATCCGAGAATTCGCG +AGAATCTCCGCCCAGCCAGTTCAGGCCAGGGCGGTCAGAGACAAAGGGCCTGGGTTTAAG +TGTGCATTTCAGAGCTGTAGAAGGCAAGCCAGATTTTTGCTGGGAAAGACCTTCATCGGG +GCGGCGAAGCCCGCAGTGACAGAGGGTCTTAGCGTACCCGTTCACATGAATTGTAAAAAC +GCACTTACATGCCATTCGTTCTTTCATTTGTTTAGTAGAATCGTTTGAACCCGGGAGGCG +TTCTTTCATTTCTACGTTCTAAAGAGCTTAATGTAGCCATTGGTATGTCCAAGGGAGAAG +TTTGAGATATTTGTGCTTTTTAAAGAAAGACAATATTTACTCGTGTATTGTGACGCTAAC +TATAAATAAAATTTAAGGACTTGGTTGGGGTAAAAGGGATATAAGGTGCTCGCAGGAACT +GGGAGACGAAGTGGAAAGCTGTATAATCTAAACGTGAGATGGTGTTTAGGGATTGGGAAT +AGCAGAAAAGAAAAAAACGTTAAAGAAATTGTAAAGGAGAAGAATAAGGTTTTGTTGTTG +TTGTTGTTGTTGTTATTGTCACAGTGAAAGGAAGAGTATGACCAGAATCAAGAGGTTTCT +TTGGTTATCTTTTGAGATAAAAGGTAGAGAACTATGTTTGAGGGGATGGGAAGGGGTTGA +AAAAATAAGTAAACGCAAATTA diff --git a/test/csq/ENST00000436063/ENST00000436063.fa.fai b/test/csq/ENST00000436063/ENST00000436063.fa.fai new file mode 100644 index 0000000..4d3da53 --- /dev/null +++ b/test/csq/ENST00000436063/ENST00000436063.fa.fai @@ -0,0 +1 @@ +1 12142 23 60 61 diff --git a/test/csq/ENST00000436063/ENST00000436063.gff b/test/csq/ENST00000436063/ENST00000436063.gff new file mode 100644 index 0000000..f002704 --- /dev/null +++ b/test/csq/ENST00000436063/ENST00000436063.gff @@ -0,0 +1,18 @@ +1 ensembl_havana gene 21 12122 . - . ID=gene:ENSG00000067334;Name=DNTTIP2;biotype=protein_coding;description=deoxynucleotidyltransferase%2C terminal%2C interacting protein 2 [Source:HGNC Symbol%3BAcc:24013];gene_id=ENSG00000067334;logic_name=ensembl_havana_gene;version=9 +1 ensembl_havana transcript 21 11410 . - . ID=transcript:ENST00000436063;Parent=gene:ENSG00000067334;Name=DNTTIP2-001;biotype=protein_coding;ccdsid=CCDS44174.1;havana_transcript=OTTHUMT00000028317;havana_version=2;tag=basic;transcript_id=ENST00000436063;version=2 +1 ensembl_havana three_prime_UTR 21 2054 . - . Parent=transcript:ENST00000436063 +1 ensembl_havana exon 21 2148 . - . Parent=transcript:ENST00000436063;Name=ENSE00001774432;constitutive=0;ensembl_end_phase=-1;ensembl_phase=2;exon_id=ENSE00001774432;rank=7;version=2 +1 ensembl_havana CDS 2055 2148 . - 1 ID=CDS:ENSP00000411010;Parent=transcript:ENST00000436063;protein_id=ENSP00000411010 +1 ensembl_havana exon 2887 2996 . - . Parent=transcript:ENST00000436063;Name=ENSE00003641262;constitutive=0;ensembl_end_phase=2;ensembl_phase=0;exon_id=ENSE00003641262;rank=6;version=1 +1 ensembl_havana CDS 2887 2996 . - 0 ID=CDS:ENSP00000411010;Parent=transcript:ENST00000436063;protein_id=ENSP00000411010 +1 ensembl_havana exon 4276 4440 . - . Parent=transcript:ENST00000436063;Name=ENSE00003655393;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003655393;rank=5;version=1 +1 ensembl_havana CDS 4276 4440 . - 0 ID=CDS:ENSP00000411010;Parent=transcript:ENST00000436063;protein_id=ENSP00000411010 +1 ensembl_havana exon 5323 5418 . - . Parent=transcript:ENST00000436063;Name=ENSE00003551497;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003551497;rank=4;version=1 +1 ensembl_havana CDS 5323 5418 . - 0 ID=CDS:ENSP00000411010;Parent=transcript:ENST00000436063;protein_id=ENSP00000411010 +1 ensembl_havana exon 7849 7987 . - . Parent=transcript:ENST00000436063;Name=ENSE00000777089;constitutive=0;ensembl_end_phase=0;ensembl_phase=2;exon_id=ENSE00000777089;rank=3;version=1 +1 ensembl_havana CDS 7849 7987 . - 1 ID=CDS:ENSP00000411010;Parent=transcript:ENST00000436063;protein_id=ENSP00000411010 +1 ensembl_havana exon 8472 10066 . - . Parent=transcript:ENST00000436063;Name=ENSE00003464563;constitutive=0;ensembl_end_phase=2;ensembl_phase=0;exon_id=ENSE00003464563;rank=2;version=1 +1 ensembl_havana CDS 8472 10066 . - 0 ID=CDS:ENSP00000411010;Parent=transcript:ENST00000436063;protein_id=ENSP00000411010 +1 ensembl_havana CDS 11281 11352 . - 0 ID=CDS:ENSP00000411010;Parent=transcript:ENST00000436063;protein_id=ENSP00000411010 +1 ensembl_havana exon 11281 11410 . - . Parent=transcript:ENST00000436063;Name=ENSE00002201976;constitutive=0;ensembl_end_phase=0;ensembl_phase=-1;exon_id=ENSE00002201976;rank=1;version=1 +1 ensembl_havana five_prime_UTR 11353 11410 . - . Parent=transcript:ENST00000436063 diff --git a/test/csq/ENST00000436063/insert-before-utr.txt b/test/csq/ENST00000436063/insert-before-utr.txt new file mode 100644 index 0000000..bbf4f82 --- /dev/null +++ b/test/csq/ENST00000436063/insert-before-utr.txt @@ -0,0 +1,3 @@ +20 G GTT . +20 G GTT . + diff --git a/test/csq/ENST00000436063/insert-before-utr.vcf b/test/csq/ENST00000436063/insert-before-utr.vcf new file mode 100644 index 0000000..4cc11cb --- /dev/null +++ b/test/csq/ENST00000436063/insert-before-utr.vcf @@ -0,0 +1,7 @@ +##fileformat=VCFv4.2 +##contig= +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO +1 20 . G GTT . . EXP=.;type=ENST00000436063:94333372-G-GTT,just before the gene/exon/utr start diff --git a/test/csq/ENST00000448695/ENST00000448695.fa b/test/csq/ENST00000448695/ENST00000448695.fa new file mode 100644 index 0000000..65f94da --- /dev/null +++ b/test/csq/ENST00000448695/ENST00000448695.fa @@ -0,0 +1,2528 @@ +>16 16:19566542-19718135 +CCAAACAGCGTATTAGCCGCAAAACCAGGTACTGGCTGAACCTCAGTTTGCGTCTTCGCT +CCGCCGCCTTCTGGAGTCCTTTCTGCCCCTAGAGGACGCAGGTGAGCTAAGCAGCAGTCA +TGCCCTTTACCATCATGACGCCCGCAGGCGGGACCACCCGGCACTGTAGACAGCTGCCCT +TTACAATCATGACTCATAGAAACTACGGCACTCTGGCCGTGGCCGACGTTGCTCCTCCGA +AGCATGGCGCCGGCGGGAGTTGTAACCCGGGCTGTCCGGAGCGGGGAGCTGCCCCTCACA +AGCATGGCGTCAGCTGAAAATGAAGCCTGTGCTGTGCGGAGCGTCGCCTGCCCCTCACAA +GCATGGCGTCTGCAGAAGGTGCTGTGCGGCCGCTGCGGGGCGGCCAGCTGCCCTTCACAA +ACATGGCGGCCGAGGGGTGCGGGGAGTGGCGGGGTAAGGATGGGAAGCCGAGCAGACGGC +CCCAGAACAAGCGGTCATGTGACTGGGAAGATGGCCGTCTTTCCTTGGTAAGGAAGCAGC +GGCGGGTGGGCTTTGGAGAGGGGCTGTCCTTACTTGTGATGGGGTCGGCCTGGGTCTGAG +AGTGTGAATTCCTCTCTGTCGGGTTCTGGTGGTCGACCGGCCACCCCCAAGTTGTCTTGA +CCGTAGAATCCCTGGCCGCTACCGCGGTCCAGCGGAGCAATCTGAAGCCAGACTGGCGGG +TTCTTGGTTCTCTCCCCGTCTGCTGCCTCTCTGCGCCTTCCACGGGCCCCTGTCCATTCA +TTCCCTAAAGAAAACTTGAGTTTCCAGGCTTCCGCGTCCCCAGAAGTTGGCGCGGGTTCT +GGGGTCGCTGGATGAGGGTAATGGTGGACTCAGCTTTTAAAGTCTGGACGAGTCGGGAGA +TCTGGCTGTTGGTCAGTTTCCTCAGCTCCTCTGTTCACCTGGAGACTTGCTTTTCTCATC +TGTAAAATGGCCGCCATTCATCCTATCCTAGGCACAGCCCTCAGACTTATTCCTTGGCCT +CAAGGAGCTGACAGTATAATGGGGCAGACGCACAGTAGAGGGATGTCTAAAGAAGGCATT +CGGATGAGGCACCAAGAAGGGAGTGATTATCCCCACCAGGGGGCTAGGGGAAGGCTTCAG +AGAGGAGGAGTTAAATTGGGTCTTGGAGGATGAATAGGAGTCCACCATAGGGAGGGCGTG +GCGTGTGCCTGGTTGGCAGGCCCGTAGGTCCCTTGTGGTTGGAGTAGCTAGGAATGAGTG +ACTGAAGCTTCAGGGTTCAGCAGGTGGTATGTGTGTGAGTGAAGAACTTGAGGAAGTTGT +GTTGTTGATGATAGTGGGATTTGGGGACGGGGAATCTCTCCTGCATCTCAGAAAGCGAGA +TAATTTACTTTCTCTTCAAATGATGTGAAGTAGCTTAGATTAAATGAGCAAATGAAAGAC +CTTAGAAATAATCAGGTACAACCTTCTGCTTTTGAGCTTGATAAACACTTCATTTTGTCT +TATTCCTTTCATTTGCCCAACACTTAAGAGACTGCTTCCTTGACACGCTACATCAGCATT +GAATGCCTCTGAGCACTTCCACACCCTGAGGTTTTTTTTTTTTTTTCAGTTAATAGTCAT +GCTGGCTGGGTATGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCTGGC +GGATCACCTGAGGTCAGGGGTTCGAGACCAGCCTGGCCAACATGGCGAAACCTAATCTCT +ACTAAAAATACAAAAATTAGCTGGGCTAAATTAGTGGTGGCACGCACCTGTAATCCCAGC +TACTTGGGAGGGTGAGGCAGGAGAGTCGCTTGAACCTGGGAGGCGGAAGCTGGAGTGAAC +CGAGATCATGCCACTGCACTCCAGCCTGGGCAACAGTGAGACTCTGTCTCAAAAAAATAA +TAATAAAAAATGAAAAAGTCATGCTGGCTTGACCAAAAAGCTAACCAAAAACATGAGAAA +CATTTGACTTCAGTGGATTTATCTGAAGTTTGCAATCAGAAAATCCAGGAAGATGCTGTC +TTAATCTCTGCATCCCAGTACATTTCTACCTTTGGAATTTTAATTTTATATTACAAGCAG +GCAAACAGGTGCCATAACGCTTTTAGTATTTAGGGTCTCTATAGTTCCTAATATGGCCGT +GCTCTAAATATTTTGTTGTTGTTGTTTTTGTTGAGACGGAGTCTCGCCCAGGCTTGATTG +CAGTGGCGTGATCTTGGCTCACCGCAACCTCCGCCTCCCGGCTCAAGTGATTCTTTGCCT +CACTCTCCCGAGTAGCTGGGATTACAGGCGATGCCACCACACCAGGCTAATTTTTGTATT +TTTAGTAGAGACGGTGTTTCATCATGTTGGCCAGGCTGGTCTCGAACTCCTGACCTTAAG +TGATCCGCCGACCTCGGGTTCCCAAAGTGCTGGGATTACAGGCGTGAGCTACCACACCCG +GCCCGTGCTCTGAACATTTCCTTTTGAAGTATGCATTCATCTTTCAGTTTCCCTAATAGA +CTTCTTGCTCCTTAAAAGTTAAAAGGACTGGCTGGGCGCGGTCACTCATGCCTGTAATCC +CAGCACTTTGGGAGGCCGAGGCAGGCGGACCACCTGAGGTCAGGAGTTCCAAGACCAGCC +TGCCCAACGTGGTGAAAGCCCGTCTCCACAAAAATACAAAAAGTAGCCAGGCATGACGGC +AGGTTCCTGTAATCCCAGCTACTTAGGAGGCTGAAGTGGGAGAATCGCTTGATCCCGGGA +GAATCACTTGATCCCAGGAGGCGGAGGTTGCAGTGAGCCAAGATCGTGCCATTGCACTCC +AGCCTGAGCTACTAAGCGAGACTCCGTCTCAAAAAAAAAAAGTTAAAGGGACTGAGTTTT +GTCCATCTTTGTATGTGGAGCCTAGAACATAATGGTGAGTGCTGAATAATATTTATGAAT +GAATGAGGAAACTGAGGAGGACTGCAGAGGAGAAATGAGTTTCTGTCATTAAATTTACAT +TTATCAAGTCCTTATTTTCTGTCAGACATCACTCGTAAAGTGCGTAACATGTAACATCAT +TAGGTTCTTATAACAACCCCATGTTGCGGAGGAAGAAATAGAGGCAGAGAGATGAAGCAG +TTTACTTAAATTAGCCCCACAAGGGATAGCTGAGGTTTGGAAGCCAGAGGCTATGATAGT +AATCATCCTCATCAGCTGGACTTCAAATCTATATCCTGGGCTGAGGTTTCTGGCTTGCGG +GGTTCCCCAAATCCCACTGCCTTGTCATGGGTCTCCCCAGGAATGCCTCTTTTTACCCAC +AGTTTTTGCTATCCCTGCTATATTTTGGCCTGGCTAGGAGATGAGATGTCCTGTATACCC +TAGATCACATTTTCCGTTTAATCCTGTGGTTATAGCACACTTGGAAATACCACCCTTTGG +ACCGGGCAAGGTGGTTCATGCCTCTAATCCCAGCACTTTGGGAGGCTGAGGCGGGTGGAT +CACTTGATGTCCGGAGTTCAAGACCAGCCTGACCAACATAGTGAAACCCTGTCTCTACTA +GAAAAAAAAAAAAATTCCTCAGGCGTGGTGACGGGTGCCTGCAGTCCCAGCTAGTCCAGA +GGCTGAGGCAGGAGAATTGCTTGAACCCAGGAGGCAGAGGTTGCAGTGAGCTGAGATCGC +GCCACTGCACTCCAGCCTGGATGACACAGTGAGACTCCGTCTCAAAAAAAAAAAAAAAAC +AACCCTTGGAGTCAGAATCTCTACATCATTTTAAGAGTTTTTTTTATGTGTAGCGGTGAA +GGGGGCTGGGTAATATTGTGATTGTGGAAGAAAAAGCTGTGTGGTCCGATTATGTGATTA +GTAACCAAAAACTTATTTGAGAATTAAAATAGTTGAGCAAAGCATTTAGTGGATTTTGGT +GTTTCCAGTATAAGGAGATTAATTTGGTTAATCATAGTGGGATTTCTGTGTATCCATATT +ATCAGAGGTAAATAATTTAAAAATAGGCCATTGTCAACCTTTAATGTGCATATAAACCAC +CTGAGGATTTAGTTAAAATGCAGATCTGATTCTGTAGGCCTGGGGTATTTCAGCCCGCCC +AGGTGATGTCATTGCTGGTGATCTGTGAACCACATTTTGAATAGCCAAGGGCTAAGCCCA +GCCAATAGTGGAGGTGTGAAATGGTGGCCTTTTTTCCTGTGGCAGGTGCCAGTGATCCAG +ACAAGCCCTTTACATTACTGGGGGTTGGAATTATGGGGAATTTTTACCAGTTTATATCAA +CTATGTTAGCAAAAAGAAAAGGAATGATTTTTGAGAAAATGCCCACAAGAGGTCGCTGTT +AGCCTTACCAAAGACCCAGAGATTAAAGAAAATGCTTTAACATCTCAGACTTAGGGATCA +GAGAGCAAATTTGAGGAAATCATCAAAGAAGTGGTAGAAAATCAAAATATGATGGTTTAC +TGTGGGCTTTCAGAAAGGAAAATAAATTTTTTTTAAGATTTATTTCCACAAGCAGTATTT +TTTTTTTTGAGATGCAGTCTCGCCTGCCGTAATCTCAGCTCACTGCAACCTCCACCTCCC +GGGTTCAAGCAATTCTCGTGCTTCAGCCTCCCGAGTATCTGGGATTACAGGTGTGTGTGA +CCATGCCTGGCTAATTTTTTTGTGTTTCTAGTAGAAACGGGTTTTGCCGTGTTGGCCAGG +CTGGTCTCGAACTCCTGACCTCAGGTGACCCACCCACCTCGGCTTCCCCCACCTTGGCCT +CCCAAAGTGCTGGGATTACAGGCGTGAGCCACTGCGCCCGGCCCAGAAGCAGTATTTTTC +ACCACCATCCCCCTTTTTAAAAAAAATAAAATTCGTTCCAAAACTTGGCTCTTTTAAGGG +AAATAGACTTAAATTTTAAAGTTCTCAACATGACTTATAGATAATCTATGGAACTACTGA +ATCTGATTCTATTGTTGCTCTCACTTTCGACAAGTTACCAACATTCTAACAGCCTCAGCT +TCTTCATCTGAAAAATCGGCTTAGTACCTACCTTATTGGGTTGATTAAATGAGGAAACGG +AGGTAAAGGCTGGCCCAGAGCCTGGTATACAGTAAGTGCATAATAAATGAGAACAGTCAT +TTGATTGTTGCATATGAAGTCATATTTCTGTTTTGATCTAGCGTTTGCTCAGCTGTTGAT +TGTTAGTAATTCCAATAGGGACAGAAAACACATTTGGAACAGACTTTCCTGTCACATTCA +ATTTTCTATTTTGTTAAATGAGCCTTTCAACATTCTACTTTTCTTGACAACAGATAAAAT +TAAGAGTCATTTGAGGCTGGGCGTGGTGGCTCACACCTATAATCCCAGCACTTTGGGAGG +CCAAGGTGGGTGGTTCACTTGAGGTCAGGACTTCTAGACCAGCCTGGCCAAAATGGTGAA +AGCCCGTCTCTACTAAAAATACAAAAATTAGCCAGGCGTGGTGACACACACCTGTAATCC +CAGTCACTTGGGAGGCTGAGGCAGGAGAATTGAGTGAATCCAGGAGGCGGAGGTTGCAGT +GAGCCGAGATCATGCCACTGCACTCCATCCTGGGGTACAAAGCAATACTCTGTCTAAAAA +AAAAAAAGTGATTTGAAAAGAGGAAAAGTGTACTTTGATGTTTTAAACTCCATCTTGACT +GTTGATGACTCTTATTCAAATTTATCCTTTGTGTTTTTTTTTTTAAATAAATCGAGGATT +GCCTGATAGCATCCTTGATGGGATGGGAGTTTGGAGGAATATTTCATAGGTGATTTCAAT +TGCAATCTTTTGGAAGATGAAGATAGTGTATATTTTGTAAATATGACCCCAGAGGGACTA +GGCAAATTATCGTGAAAGGGATTTTCCCTTAAAAAAAATAAAAGTAGGGGCCAGGTGCAG +TGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGCAGATCACGAGGTCGG +GAGATCGAGACCATCCTGGCTAACACAGTGAAACCCCTATCTCTACTAAAAATACAAAAA +AATTAGCCGGGTGTGGTGGCGGGCGCCTGTAGTCCCAGCTACTAGGGAGGCTGAGGCAGG +AGAATGGCATGAACCTGGGAGGCGGAGCTTGCACTGAGCGGAGATCGCGCCACTGCACTC +CAGCCTGGGCGACAGAGTGAGACTCTGCCTCAAAAAATAAAATAAAATAAAAGTAGAACT +GGTTCATTATTGTCAACCAGCCTTTCTCCTCCTTTCCTACACTTGAAGCCGAGTTCATTT +AGAAAGGATAGAAATGAAATGACATGGGAGCTCAATTCGTTTGTGCTGGCTTGGGTTTCT +GGGTTAATGGAGGATATTGGGTAAAGCTGACTAGTTGCACGGCACAATTAGATCTGGGGT +GCTAGTATTTCATACAAAGGTTAATGAAGTTGGGAATCTAAATGGGAGCAGAAGATGGGG +TGGGGGGATGAATTTAAGGGACTTGGAGGCCAGGGAAAGTCCCTGTGCTCTTTGAGGTTC +CTCTTTCCCTAAAGTGGGTTGGGAGGGACAAGAATTGTCCCGTGTGCCCAGAAAAGCTGT +TTTACTGGGATGGGATATTTTACAAATGAGAAGTGCACATGTCTTTTGTTAAAGAAAAAC +TATTGGCTGGGCTCAGTGGCTCACGTTTCTAATCCCAGCAGTTTGGGAGACTGAGGCAGG +TGGATCACCTGAGGTCAGGAGTTCGGGGTCAGCTTGGCCAACATGGTGAAACCCCGTTTC +TAATAAAAAATACAAAAATTAGCCGGGCGTGGGGGTGTGCCTGTGGTCCCAGCTACTTAA +GAGGCTGAGGCAGGAGGATGGCTTAAACCTGAGATGCAGAGGTTGCAGTGAGCTGAGATC +GCACCACTGCACTCCAGTGAGACTCTTATGTCAAACAAAAACAAAACAAAACAAAAATAT +TATTCATGGTGCTTGTTAAAGGAAATGAGACAGGCTTTATTCCGGGGGGCTACTATAGTG +GGGTTTTGCAATAGGGGACAGAGATTGGCCTCAGCTCCTAATGCAACAAGGAATAGTGGG +AATTTATAGCCAAGTGGGGGTAGAAGAAGAATTCGATCAGATATTGAGGGCAGCTGGATA +TGGAGGGGGATTCTGGCTCAATCAACTTGACAGAATTCTTGCTAAAACTGGGCGGTGCAA +ACACAAACATGGAAATCCAATAGCTGAGCACTAGCTGGGGAGAACTCAGAGGAACCTGCC +CAGAGTTTGGTCAAGGAGAGACTTTGTCACTTTCCATACTAGCTGAGATGTTCTGCTTGG +AGAGTCAATGGAGGAGATGAGAAAGGGGTCAAATGGGTTAACTTGTCTATGACTTTGTGG +CCCTGACGTTCTGTGACTATGGTAGCTTTTAAAATTATATGTGGATACACACATTGCATA +AACAATTTGGTTAAATATGTGAGTTAAAAAAGATTTTAAACCATAACCTATGAAATTAAA +TTCTCAGATCTTCATAATAGAGATTAAGAAATGTAAAGACAATCATTTAAAAACATTTTC +TGCCTTCCCCCCACTCCTGTGTTCCTCTCCTTCAGATTTTTTTTTCTTTTTAAGAGAGAG +AGACTCATTCTGTTGCCCAGGCTGGAGTGCAGTGGTGCGATTATAGCTCACTGCAGTTTT +GAGCCCCTGGATTCAAGCGATCCTCCCACCTCAGCCTCTAGAATAGCTGGGACTACAGGC +ACACACCACCACACCCAGCAAATTTATTTATTTATTTATTTATTTTGTAGAGATGGGGTT +TCGCCATGTTGCTCAGGCTGGTTTCAAACTCCTGGGCTCAAGCAGTCCACCCATCTGTAC +CTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCATGCCCAGCAGAGAGAATTTCGTAA +AAGGAAAACGGATACTTTATTTTCAAAGGAGCAACAATAAGACTACTATTGCAGCACAAA +GATGAGCACAGAAGACACAGGGACCGTATCTTTAAAATGCTCAAAGAAGGCTGGGAGTGG +TGGCTCATGCCTGTAATCCTGGCACTTTGGGAGGCTGAGGCAGGAGGATCACTTGAGCTC +AGGAGTTTAAGACCAGCCTGGGCAACATAGGAAGATGCCAACTCTCAAAAAAACTTAAAA +AAAAAAAAAAGAAAAGGAAAAATTCTGTTTGGTTTCTATAAATTTTACTATGAAGGCTCC +AAGTGTGTTTTGTTTATTTGCTTTTGTACTTGTCCTACTTGGGCCACAGATGTTTCTTGA +GTCTGTAGCTTGATGTCTTTCTTTGGTTTTGGAAAAGTTTCACCTATTATCTCTTCAGAG +ACTGTTCTTGCACATTCTCTCTCTCCTCCTCTTTGGGATTCCAGTTATATGTGTGTTAGG +CCTTCTCTTCACGTTGCTTGTGTCTTTGAAATTCTGCCTGTCGTCCTGTTCTTTTTCTGC +TCCATGCTTCAGTCTCCCCCTTTATTTTCCAGCTCACAAATCCTTTCTCTTTTTGAACCC +TCAAGAAACCAATGAAAACACAGTGAGCTCTTCATCTCCTTTCTGCGTGGCTCCTTTCTC +TTGCCCTATGCAGCTCAATGGGCGAATACCTTGAGGGGAAATCTGGGCTGGATTTCTGTC +TTCTCTGTGCTCTCTCCTCTTCCTCCTGGCTGTCTTGATAGCCCTGAACTCCTGTTTATC +TGTGCAGCTCTGTGAGGTTTCCTTAGAGCCTTTTTAGCTGCTCTGCTGCCTCACAGCTGC +CCTGTGCTTGGCGTCAGCCTCTTGTCCTGTGCTGAGAATTCACAAATGCCCTCAGCGGGA +AAGCTGGGCAAGGAGTGTTAGAGTCACCTTAGTGAGTTTCCCTTTGTTCTGGTGTGTGGC +ATAACAAGTCCAGTATGCTGGCAGCTGTTTATACCTTCAAATATATATATATTTTTTGAG +ACAGAGTCTCACTCTGTCCCCCAGGCTGGAGTGCAGTGGCATGATCTCAGCTTACTGCAA +CCTCCGCCTCCTGGTTGAAGCGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACA +GACATGTGCCACCACGCCCGGCTAATTTTTTGTATTTTTAATAGAGATGGGGATTCACCA +TGTTAGCTAGGATGATCTCGATCTCCTGACCTCGTGATCCGCCTGCCTCGGCCTCCCAAA +AGTGCTGGAATTATAGGCATGAGCCACTGCATCCGGCCAAACAGATTTTTTAAAATGTTG +TGTTTTGTTTTTTGTTTGCCATGGAGTCTCGCTCTGTGGCCCAGGCTGGAGTGGAGTGGT +GTGATCTCAGTTCACCGTGACCTCCACCTCCCAGGTTCAAGCGATTCTTCTGCGTCAGCC +TCCCAAGTAGCTGGGATTACAGGCGTGCGCCACCATACCCACCGAATTTTTGTATTTTTA +GTAAAGATGGTATTTTACCATGTTGGCCAGGCTGGTCTCAAACTCCTGACCTCACGTGAT +CCACCCACCTAGGCTGCCCAAATTGCTGGGATTACAGATGTGAGCCACTGCGCCTGGCCA +AAAAGTTTGTTTTTAAATGTAGTTTCTTTTTAACTTTGGTGGGAATATTGTGCTGTTCTA +AACTACCTTGTCATTGAAGAAGTCTCATCAGAAGTTTTTAGTGTTTTAAGTACCCCCATC +CACTAATTGGCTGTGTTTCGCTGTTTACCAGGCACTCCAGGAATAGGAACTACAAAGCTG +AATTTGCATCATGCCGACTGGAGGCTGTACCATTGGAGTTTGGGGACTATCACCCTCTGA +AACCCATAACTGTAAGTTTTGTTAAGGGTCTTTCTGAATGATATTCTTATCCCTTGAAAT +GAAAGACAATCTTCCTGAGTCTTTTCCGTTTTGCCAGTGGTAGCCACTTTTGCATATTTG +ATTTTTTTTTTTTTTTCAGAGTCTTGCTCTGTCGCCCAGGCTGGAGTGCAGTGGTGGCTC +ACTGCAACCTCTGACCTCTGCCTCCTGGGTTTAAGCGATTCTCCTGCCTCAGCCTCCCGA +GTAGCTGGGGCTATAGGCACACGCCACCATGCCTGGCTAAGTTTTTGTGTTTTTTTAGTA +GAGATGGGGTTTCGCCATGTTGCCCAGGCTGGTCTTGAACTCCTGAGCTCAGACAGTCTG +TCCACCTCCACCTCACAAAGATTATGGGTGTGGGCCACCGTGCCCAGCCTGATTTATTTT +TGAGATGGAGTTTCACTTTGTAGCCCAGGCTGGAGTGCAGTGGTGTGATCTTAGCTCACG +GCAACCTCTGCCTCCCAGGTTCAAGCAATTCACCTGCCTCAGCCTCCTGAGTAGCTGGGA +GTACAGGCATGCACCATCACGCTTGGCTAATTTTTGCTATTTTTTTTATTTTTAGTAGAG +ACAGGGTTTCGCCATGTTGGCCAGGCTGGTCTCGAACCCTTGACCTCAGGTGATCCAACC +ACCTTGGCCTCCCAAACTGCTGGGATTACAGGAGTGAGCCACCTCGCCCGGCCTGCATAT +TTAAATCAACCAGTTTGTTCACTGCCTCTTTTTTGTAATATTGGCCTCACCTAGCACCAT +TTTTACTCCCTTCCTTCCTCCTTAGTGAGGTTCCCTTGTGAATGGGATGACTTTGTTCCT +GATTTGGCTGTGTCAACAAAATGTATCTTGACTTTTAATTTTTGTATTTGGAATATAAGA +GTCACTCTAATTGCCAGCAGAGAGTGCTGTCCTGAATAGCATCTTAGTCTATCTGTGGGT +TTATTTAAAAAATAAAAACAAAAGCAGGCAAGAGACTTGGCTGGTTCCTCTCTGCCAGGT +TGGTACTGTCTTATTAGCAAGTAATAGAAACTACACGGTTGTCATGTTGGGGAGAAGAGA +AGATGTGATTGTCAGCATGGAGGCTCTGGGAATGTATGGAGATGATTGCATAAAGCAGAA +GACCCCAAGACTGAGATTTAGCCTCCCAGGACCCCTTCAATCCCCATGCTGTTGTGTGGC +TGTGGGTGACCTCAGCACAGCCACAGTTGCGTTCATTCTCAGGTGCCCGTTCCCCATGTT +AAAAGAAAATTCTTGGCCGGGCTCCATGCCTCACACCCGTAATTTCAGCACTTTGGGAGG +CTGAAGTGGGTGGATCACCTGAGGTCAGGAGTTCGACACCAGCCTGGCCAACATGGCAAA +ACCCCATCTCTACTAAAAATATAAAAATTAGCTGGGCATAGTGGCATATGCCTGTAGTCC +CAACTACTCAGGAGACTAAGAGAGGAGAATCACTTAAACCCAGGAGGCAGAGGTTGCAGT +GAGCTAAGATCACGCCACTGCCCTCCATCCTGGGCAACAGAGAGAAACTCCATCTCAAAA +AAATAAAAGGAAAATTCTGAGCCAAATTAAATTTAATGGAGCTTAATTGAGCAAAGAATA +ATTCATGAATTGGGCAGCCTCCTGAGCCAGAGTAGGTTCAGAGAGGCTCCAGCACAGTCA +CGTGGTAGAAGATTTATGGACACAAAAAGGAAAGTGACATTCAGAAAATAGAAGTGAGGT +ACAGAAACAGCCGGATTGGTTACAGTTCAGTATTTGCCTTATTTGAACCCAATTTGAACA +GTTGGCCCCCCCCTTTTTTTTCTTTTTTTTGAGACAGAGTTTCACTCTTGCCCAGGCTGG +AGTGCAATGGCACAATCTCAACTCAGTGCAACCTCTACCTCCCGGGTTCAAGTGATTCTC +CTGCTTCAGCCTCCTGAGTAGCTGGGACTACAGGCGCCCGCCACCATGCCCAGCTAATTT +TTTTGTCTTTTTAGTAGAGACATGGTTTCACCATGTTGGCCAGGCTGGTCTCAAACTCCT +GACCTCAGGTGATCCGCCTGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGTATGAGCCA +CTGTGCCCGGCCCAGTTGGCCCCCTTTAATTGGCCAAAACTTGGTGATTGGCACAAGAGT +AGGTTACACTCTGTTTACATGTCCAATGAGGTTATAGTTCACTATGTGCAGAGAAACCTT +TAGGCCAAACTTAAAATAGGTAAGGAGACAGCTTTAGGCTAAACTTGATTTAACACCCAT +ACCATAACAGAATAGCTGAGAAGAGCTGCTGCAGCTCCAGGCCTATCCTGTTAGGTTAGC +AACATCAGCAGCAGGAAAATGCTTTTCTCAAGCAGTTTTCATTGACCCAGTTTTGTTATG +CGCCCTACCCTGAACCAGCATTGGTGACCTGCTGTATAGAATAAGTTGATAGATTGGGGT +AGGTCTAATGCTCACCTTGGGAACTGAGAACAGAGTTCACCCCACCAGGCCTGTAGGAAC +TGAGTGTGGGGGAGAGATGTTTTCTCAAATAAAAATTGGGGTATTAAGTATTAAGCCTGT +GAGGTGGAGGAATGGGTGCCAGGCAGACAAAAACAGCAAATGTACCCCAATGGGAGGTGC +TTCTCTCCCTCCCCTAGACTGCAGTTCAACTCCATTCAGGCAGCCATCGCCGGCAGTTGG +CATCTGACTCGACAGGTTTGAGGGCAAGGTCCTCAGTGAGACAGCCCTGGCCCAGTATGG +TAGCTCATGCCTGTACTCCCAGCACTTTGGGATGCTAGATGAGAAGATCCCTTGGGCCCA +GGAGTTCGAGAACAGCCTTGGCAACATAGTGATACCCCACTTCTACAAAAAGTAAAAAAA +CAATTAGCAAAGTGTGATGGTGTGCTTGTAGTCCCAGCTACTCAGGAGACGGAGGCAGGA +AGATTGCTTGTGCCCAGGATGTCGAGGGTACAGTGAACCGTGATCACACCATTGCACTCC +AGGCTTAGTGACAAAGCGAGACCCTGTCTCCAAAAAAAAAAAAAAAAGACATCTTCACTT +CAGAAACTCCAACTTCGCTACACATTGGGAGTTCCCATGCCTCCCTCCCTCATGTTCAAT +AATTTGCTATAGTGGCTCACAGAACTAGGGAAACATTTACTTATACTTACCAGTTTATTA +TTTAGTATTTACTTGTACTTAACAGTTTATTATTAAGGATATTACAAAGAATACAGATGA +ACAGCCAGATGAAGAGCTACGTAGGGTGAGGCCCAGGGGAAGGGGCACACAGAGCTTTCA +TGTCCCCTCCAGGTACCTCGATGTGTTCTTGTTCACCTACCTGGAAGCTCTTCAAACCGC +CCCCCCCTTTTTTTTTTTTGAGACAGGGTCTCACTGTATCGCCCAGCTGGAGTGCAATGG +CACATTCTCAGCTCACTGCAACCTCTGCCTCCCAAAACCCCATTTTTCATGTTTTTTTTT +TTTTGAGGCATCGTTGCATAGGCATGATTGATTATTCATTCGGTCTCCAGCCCTCTCACC +TTCCCGAAGGATGGGGAATGGGGCTGAAAGCTCCAATCTTCTAATCATGGCTTGGTCTTT +CTGGTGACCAGACCCCATCCTGAAGCTCTGCAGGAGCCCATCGGGAGTCACCTTATTAGG +ACAAAAGATGCTCCTATCACCCAGGAAATCTCCTAGGGTATTAGGAGCTCTGTGGGAGGA +ACTGGGGGCAGAGACCACATAAATTTAACAGCTTGGAGTGCAGTGGTGCGATCTCGGCTC +ACTGCAACCTCCACCTCCTGGGCTCCAGCCATCCTCCCACTTCAGCCTTCTGAGTAGCTG +GGACCACAGGCATGTACCACCACACCTGGATTATTTTCATATCTTTTGTAGAGATAGGAC +TTCACCATGTTGCCCAGGCTGGTCTCAAACTCCTGGCTTCAAGTGATCCTTCTGCCTCAG +CACCACAAAGTGTTGGGATACAGGCATGAGCCACTGCACCCAGTAGAAAACTTAACTTTT +ATGAGGTGTTCAAGGGAGAAAGGCAAAAAAAAAGTACCTGGTTAAAGTAGAAATTCCCTA +CTTAGATGTTAGTTGTTGGTTTTGATTGGTAGTCTCTAGTTAGTGGGTAGTTGGCGATTT +GCAACTGATTAAGCTTAAGTTCCATTTTGCTACTTATATTGAGTTGGATTTTGGTTTGCT +ACATAGGGAACCCCAGGTGCTGTAGCCATCTCAGTCCAGTGACCTCTCAATTAATTTTTT +TAACACTTCCTAACCCTAACTTCCTACTTTCCCTTCCTTGACAGTTGTGATCCTGAGTCA +TGTCCATTTGTCACAAAAACTAAGCATCCCCTGCAGATGGTTAAGTCTCTGCTGCAAATG +AACCATCCATTCAACTACCAGAATGGGAGGAAAGTACCCACTGGAGTGTTTCACTGGAGA +GAGTTGTGGGAGTTCCGTTTTACCTCCAGAAATTTTCCTCACAGGTCACAGAGTCAAAGA +CAAAGAAAGTGAACCGGAAAGGAAGCACTTCTTCCACGTCCTCCTCCTCCTCCAGCTCCG +TGGTGGACCCGCTGAGCAGCGTCCTCGATGGGACTGACCCCCTCTCCATGTTTGCAGCCA +CTGCTGACCCCGCAGCCTTGGCAGCTGCCATGGTAATGCACCCCAGCCATGGTCGTCCAG +TGGGGGTTGGTTTTGTGGGTGCAGGAATGGGTGGTTTTCTTGTGCCCTGCCCTTTTTTTT +CCCCTGAGAGACAGAGTCTCACTCTGTCACCCAGGCTGGAGTGCAGTGGTGTGGTCATGG +CTCACTGCAGCCTCCAACTCCGGGGCTCAAGCAATTCTCCCACCTCACCCTCCTGAATAG +CTGGGATTATAGGTACACACTACTGTGCCGGGTTAATTTTTTATTTTGTTGTAGAGGTGG +GGTCTTGCTGTGTTGCCCAGGGTGGTCTTGTACTCCAAGCCTCAAGCGATCCTCCCACCT +GAGCCTCCTAAAGCTTCTTCCCCTTTTTTAAGTTGCACAAGTAATGCACACGGTACCTTC +TGGTCAGGTCATCCTGACATGAGAGGCTGGTGTAGCTCTGTGAAGTCTTTTTGTTTTTTT +GTTTGAAAGCATTTTAAAATTTATTTTTATTTTTTAATTTAATATTTTTTTCAGACAGCC +TTGCTGTGTCACCCAAACTGGAGTGCAGTGGTGCAATCTCACTGCAGCCTCCGACTCCGG +GTTCAAGCAATTCTCTCACCTCAGCCTGCCAAATTGCTGGGACAGGCATGCACCACCATG +CCCAGCTAATTTTTGTGTTTTTTGGTAGAGATGGGCTTTCATCATGTTGACCAGGCTGGT +CTTGAACTCTTGACCTCAAGTGATCCACCTGCCTCAACCTCCCAAAGCACTGGGATTACA +GGCGTGAGCCACTGCACCTGGCTCTTAAAATTTATTTTTAATTTTAATTTTATTCTTCTT +ATAAATCTTTTTACATAATACATAAGTAAATCACTCATTTTGATGTGAAAAAGTCAGACA +CTACAGATAAAGTCATGTAGAGCAATCCTCATTCCAATCTCCACCCTGGCGGTTGTGAGA +ATGATGGCTGTAATGTGTCTTCTTCCATAGCTTTTCCCCTGTATTTTCATAGATACTTGC +GATAGCAGTTTCTGAGCATTCCCATACGTACTCATATATAAATAATTACAGCATCAACTT +ACTGCATGGCAGGCATTTTTCCGGAGTGCGTTTTGTATTTGGTTCTCTTACTACCTTGTG +AGAGGTATTGGAATCCTCATTAAAGAGGCAGCCATGGAGGGATAGAGATAACAAGTCACA +TCCAAGCTGGGATTCAAACCTGGCCAGTCTGACTTCAGAATACATGCTCTCGATCATCAT +CCTATGCTGTGTTTCATATATATATATATATATATATATATATATATATATATATATATA +TATATATATATTTTTGAGATGAAGTCTCACACTGTCACCCGGGCCGGTGTGAAGTGGGGT +GATCTCGACTCGCAGCCTCCACCTCCCAGGTTCAAGCGATTCTCCTGCCTCAGCCTTCCG +AGTGGCTGGGACTACAGGCACGTGCCACCATGCCCAGCTAATTTTTGTATTTTAGTAGAG +ACGGGGTTTCACTATATTGGCCAGGCTGGTCTCGAACGCCTGACCTCGTGATCCACCCAC +CTCGGCCTCCCAAAGTGCTGCAATTACAGGCGTAAGCCACTGTGCCCGGCCTGTGTTTCA +TATATTATTTACCATTGTTACATAAATGGAACTGCTGTTTTGTGACTTGTTTTTTTGGAG +ATAGTCTTGCTCTTTTGCCTAGGCTGGACTGCAGTGGCATGATCATAGCTCGCTGCAGCC +TTAAAGTCCTGGGCTCGAACAATCCCCCTGCCTCAGCCTCTCGAGCAGCTGGGACTTCAG +GTGTGTGCCACCGCACTCAGCTAATTTTGGATTTTTTGGTAGAGTTGGGGTCTCACTGTG +TTGCCAAAGCTGGTCTCAAACTCCTGGGCACAAGCAATCCTCCTGCCTTGGCCTACCAGA +GTTGCTGGGATTACAGGCCTGAGCCACTGCACCCCACAACTTTTTTTTTTAATTTATTTT +ATTTTATTTTATTTTATTTTTTTGAGACGGAGTCTCATTCTGTTGCCCAGGCTGGAGTGC +AGTGGCGCGATCTTGGCTCACTGTGACCTCTGTCTCCTGGGTTCAAGTGATTCTCCTGCC +TCAGCCTACCTAGTAGCTGGGATTACAGGCATGTGCCACCACACCTGGCTAATTTTTGTA +TTTTTTGTAGAGACAAGGTTTCGTCACATTGGCCAGGCTGGTCTCGAACTCCTAACCTCA +GGTGATCTGCCCACATTGGCCTCCCAAAGTGCTGGGATTACAAGTTTGAGCCATGCCGCC +CAGCCAACTTTTTTTTTTTTTTTAACTTGACCATATGTCTTGGAGAACTATCCATGTTAG +TACATTTAGAACAACCTTATTATTTTGACCAGCCGTATGGTATTCTAAAGACTGGATTTA +CCTATTTTAATTTACCATTCCTCTACTGATGTATCCATCAGATGGAGGATATCCCAGATA +GTTTCTGGGTTTTGCTGGTACAAACAGCAGTGCAGCATGTGTCTCGAACACACACACATC +TTGGTGCATGTCTGCAAGGATTTCTGCAGGATAGCTTCCTAGAAGTTCTTTGCTGGTTGG +CCAGGCGCAGTGGGTCACGCCTGTAATCCCAGCACTTTGGAAGGCTGAGGCGGGCGGATC +ATGAGGTCAGGAATTCGAGACCAGCCGGACCAACGTGGTGAAACACCATCTCTACTAAAA +ATACAAAAATTAGCCAGGTGTGGTGGCGGGCACCTGTAATCCCAGCTACTCGGGAGGCTG +AGACAGGAGAATCACTTGAACCTGGGATGCGGAGATTGCAGTGAGTAGAGATCACGTCAC +TGCACTCCAGCCTGGGCAACAGAGCGAGACTCCATCTCTTTGCTGGCATAAGGCAATGTG +TATTTAAGGTTTTGATGGCTATCACCAAATTGTCCTCCAAAAAGAGTTAACCAGTCTGCA +TTTCCACCAGTGATGTTGAAGAGGGTCTGTTTCCCTGCATCCTTGCCAGCCTGACATCAG +CCAGCATTTTAACTCTTTGACATTCTGATAGTTGAAAAAGTGGTCTTTTCCAACTATCCT +TTCCTTAATTCTTAATGAGTTTGAGCATTTTTTGATATGTTTATTGTCCATTTATGATGA +AATGGTCTGAATTTTTTTTTTGAGATGGAGTCTTGCTCTGTCACTCAGACTGGAGTGCAG +TGGTACAATCTTGGCTTACTGCAACCTCTGCCTTCCAGGTTCAAGCGATTGTCCTGCCTC +AGCCTCCTGAGTAGCTGGGACTACAGGCATGCACCTGGCTAATTTTTGTATTTTTAGTAG +AGATGGGGTTTTACCATGTTGGCTAGGCTGGTGTTAAACCCCCGCCCTTAAGTGATCCGT +CCACCTTGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGGCACCATGCCTGGCGCTGTA +ATTTTTTTTATGATAGTAAACCTTGAGACAAATCTCTTTTATTCCACAGTAAAGGACTAT +CTGGCTTCTATTTATATATGTATATATTTAAAGATCAAAATGATATTGCTGCTGAAGAGA +TTATCTTGCCTTTCTTTAGGACAGCTCCAGAAGGAAACGTGATAGAGATGATAACTCCGT +TGTAGGATCGGATTTTGAGCCTTGGACCAACAAACGGGGAGAAATCCTTGCCCGGTACAC +CACTACCGAAAAGCTGTCTATTGTGAGTACCAGGAGACCCTCTCCAGAGTCTACTTTGGA +GTTAGTAGTAATTTCTTTTTGTTATGTTGCTTCAACTCCTGGGCTCTGTAAGTTTCACTT +ATTTATTTATTTTTCTACTTCTCTTAAAAGCTCACATATAAGGCTTCATGTAGTATGTCA +GTGTTGTTGGCAGAAAAATGTGCTGACAGGTTTCCCAAAAAAAAATGTTAAGGATCAGGG +ATGTGGCACAGGCCAGAGAAAGAATTAGAACAGCAGAGTCTTGTCTTTGGGAGGAGGTTT +GAATTATGAAGGGAGGAGGTCGGGCACGGTGGCTCACGCCTGTTATCCCAGCACTTTGGG +AGGCCAAGGTGGGCAGATCACTTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACATAGT +GAAACCCCATCTCTACTAAAAAAATTAGCCAGGCGTGGTGGCGGGCACCTGTAATCCTAG +CTACTCAGGAGGTTGAGGCATGAGAATTGCTTGAACCCGGGAAGTGGAGGTTACATTGCG +CAGAGATCACGCCACTGCACTCCAGCCTTGGTGACAGAGTGAGACCCTATCTCAAAAAAA +ATTAATTAATTAATTAATTTAAAAAATGAATTAAGGGAGGAGAGCACAACACTGGAGGAG +AAAGGTGTCACTCAGTAAGTCCCATATAGCTGGGTTTTCCCCTGGAGCTGGAAATTTACT +ATTTCTCTGGATGGCCATTAGGTGAAGTAGTTGGCTTTGGCCTCAAGACACTTACGAAAT +TCGAGGCTTACCCTTCACTTGGCAAATTGCTGTGGAAGGAAAGACTCAGGAGAGCTGAGA +CCAACCCAGTCAGGTTAATGCCTGTGTGAGTTAGGACTGGGTTCAGTTGCTTAGAACTAA +AGCCCCTGCTAACATTGTAAACAAGAGTGACCTGTATCCCTCCTTACGCTGGAGAAAAGT +CTCGAGGAGAGGAGTCCAGGGCTGGTTTGGCAGCTCCGAGGGCATCAGGGTTCCGCCGCA +TTCTTTCTTGCTCCTCGGCTGTGTTGAGTGTTGCCTCACATTCATGTTGGTAGACAGAGG +GAGGAAAGGGAAAGAAAGATGCGCCCCCTCCCATTTAGGAAGACTTCTTGGGGTCCCGCA +ACACTTTTAGTTACATTTGTCTTGAAGGTGTGATCATGGGCCACGCATAGATGCAGGGAG +GCTGAGAAATGTAGCAGCGTGTCCATCTACAAATGGGGCTGTGCCCTGGAGGAAACAGTG +AACTTGGCAGGCCATGGGGAACGCTTGGCCTCAACGCCTCTTCTCTTCATTTTTTCCTCC +CAGGGTGTGTACTCATTGAACAGAATGATAGGCAGAATTGCTGGACTATTTAAATTGAGT +CTTTTTTTTTTTTAACTGTACAGAGTTAACTTAGAGCAGTGATTCTCAACCAGGAGTAAT +TTTTACCCCTGGGTCATCATTTGGCAATATCTAGAGACATTTTTGACTGTCACAGTTCTG +GGGGTGGTACTGACATTTATTGGGTGGAGGCCAGAGATGGGGCTAAACATCCAACGGTGC +ACAGAATTAATCTCCCACAAAAAGTTATCTGGCCTCAAATGGCAGTAGTGTAGAGGGTGA +TAAACCCTGATTCAGAGTAGGTTAAAAATAGTTCTATTATGTGACTCCGCTGTCATATCA +AAAATTTTAGTATTTGTCTGCTGACTTTGAGAACCCTGACTTGAGTAGAAATTTGAATCT +CCAGTGGTTTTTAGTGACTGTATTTTTCTTCTTTGAATATATATTTCTTTCTCTTGGGTA +TGTAAATGGCTCTGTTGGAAAACAATGAACATACTGCCTTCGATTTTTAAAATATTAATG +AATTTTATGTCTCTGCAGAATCTGTTTATGGGATCTGAAAAAGGTAAGATGAGTTTGTTG +TTGTTTTGATGGGAAAATTCTGGCATTACTTTTAGTATAATTTTACAAAGGAAAAAAGTT +TTATGTGATATGATTCTGATGTTTGATTCAGTTGGAGCTGCTATTTCTTAGATTGTGGAT +AGACGTAGAAATAAAATACATATTTAGAGCATGAATTAAAAAAATACCAAATACCAGCAC +TTTGGGAGGCCAAGGTGGGTGGATCATCTGAGGTCAGGAAGTTTGGTACCAGCCTGGCCA +ACATGGTGAAATCTCGTCTCTATTAAAAATACAAAAATTTGCTGGGCGTGGTGGCGCACG +CCCGTAATCCCAGCTACTCAGGAGGCTGAAGCAGGAGAATCACTTGAACCTGAGAGGCGG +AGGTTTCAGTGAGCCAAGATTGCATCATTGCACTGCAGCCTGGGTGACAGGAATGCCGTC +TTAAAAAAAAAAAAAAAATACAGCCGGGCACGGTGGCTCACCTGTGTAATCCCAGCACTT +TGGGAGGCCAAGACAGGCAGATCGCCTGAGGTCAGGAGTTTGAGACCAGCCTGGCCAACA +TGGTGAAACCCCATTTCTACTGAAAATACAAAATTTTGCTGGGCGTGGTGGTACATGCCT +ATAATCCCAGTTACATAGGAGGCTGAGGCAGGAGAATCGCTTGAACCTGGGAGGCGGAAG +TTGCAGTGAGCCAAGATTGCACTCCAGCCTGGGCAACAAGAGTGAAATTCCGTATTAAAA +AAATATATATATATGGCCTGGTGCGGTGGCTCACACCCGTAATCCCAGCAGTTTGGGAGG +CCAAGGCGGGCAGATCACTTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACAATGTGAA +ACTCCATCTCTACTAAAAAAAAAAAAAAAAAAAAAAATTAGCCAGGCATGGTGACAGATG +CCTGTAATCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATCGCTTGAACCTGGGAGGCGG +AGGTTGCAGTGAGCCAAGATCGTGCCATTGCATTCCATTCTGGGTGACAGAGCGAGACTC +TGTCTCAAAAAAAAAAAAAAACAAAAAAAAAAAACAAAGAGGTTACTAGGAGTAAAACGT +AAGCTTACTGTTTAAGAATTACAGAGGAAGTAGTCTCCCCCTCATTGTGCCTCCCTCACC +AACTGGGTTTTAGAGAGCCTTTCCCTTGCCTTAAGTCTTTTCCCTTGTGCAATAAGGTAT +GTTGGTGAGGGGGTCACATGCTTAGTCTTATACGTCACTGGTCCCTGAATGCAGTTCTCA +GCTTCCTCTCCTAAGACACACAGTCAGAAGCTCTGGACCAGGGTGTCTCAAACTGCCGTG +TAGCAGGATTTCCTGAGGAACTTTTGTATGAATATAGATGCCTGGCCCCCACTTGCTCAA +TTAATCTTGCAGGATGGGACCCCAGAATTCCTATTTTGATGCTCCAAGGGGATTCTGGAG +CAACTGACGGATCATGTGCTGCTGGGTGCAGATGAGCACAATCATAGTTCATTGCAGGTC +TCTGATATGGCAGCTGCCACTCTCCCCACGGCTCTGCTGGATGAGACAGCACGTTAGAAA +TCAAGAGAGTGGGAACAGCTTTGTTATGCATAGAATTTTTTTTTTTTTTGAGATGGAATT +TTGCTCTGTCACCCATGGTGCAGTGCAACCTCTGCCTCCTGGGTTCAAGCAATTCTCCCA +CCTCAGCCTTCTGAGTTACTGGGACTATAGGTGTGCACCACCAGGCCCAGCTAATTTTTG +TATTTTTAATAGAGACAGGGTTTCACCATGTTGGCCAGGCTGGTCTCAAACTCTTGACCT +CAAGTGGTCCACCTGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCTACCACG +CCCAGCTTGTTATGGACAGAATTTTGATCCCAGACCATAAAAGGTAAATCATACCCACCA +GTTTGTAAAGATCAAATAGAGTGATGATACCAAGTGTCTTAGTTTGTTTAGTGGTACTAT +AAAGGAATACCAGAGGCTGGCTAATTTATAAGGAAGAGAGGTTTACTTGACTTATGGTTC +CACAGGCTATATAAGAAGCATGGTGCAGCATCTGCTGTTGGTGAGGGCCTCAGGCTGCTT +CCACTCATGGTGAAAGCAAATGAGAGCAGGTGTGTGCAGAGATTGCATGGCAAGAGAAGG +GAGGAGAGAGAGGGAGAAAATGCCAGGCTTTTTTCAACAGCCAGTTCTCATGGGAAGTAA +GAATAACTCATTACTGCACTCATTACTGCAAGGATGGCACCAAGCCGTTCATGGTGGATC +CCCCACTACAACCCAGACACCTCCCACCAGGCCCCACCTCCAACACTGGGGATCACATTT +CAAAGATGAGACTTTGTATGAATATAGAGCAATAGGAGCTCTCATATGCTGCTGGTGGGA +ATGTAAAATGGCACAACCACCTTGTAGAACACTTTTGCATTTTTTATTTTATTTGAAGAC +AGGTGCTGTGGTCTGGTTGTTTGTGCCTAACCCCACTCCCCTGCCCCGATTCATATGTTG +AAATCCTAACCCCAAGATGATGGTATTAGGAGATGGGCCCTTTTCAGAGGTGATTAGGTC +ATGAGGGTGGAACCCTCATGAATGGGATTAGTGCCCTATAAAAGAGGTCCAAGGGCACTC +CCCTCACCCCTTCCACCAAGTGAAAACACAGCAGGAGGGCATCATCTATGAACCCAACCG +GAAAGCAGGCTGTCATCAGGCACTGGGACCTAATCTGCTGGGACCTTGATCTTGGACTTC +CCAGCCTTTAGGACTGCGAGAAATACATTGCTCTTATTTATAAGCCACCCACTTTGTAGC +ATTTTGTTATAGCAGCTCAAAGGGATTAACACAATGAGCCAACCCTTTGATCCAGCATTC +CACTACTAGGGGTATCCCCAGATCAGGGGTTGGTAAACTGCATGCTGCAGGCCAAGTCTG +GTCCACTGCCTGTTTTTTAAGTACAGTTTTATAGGAACAGAGCCCTATCAATTTGTTTAC +ATATTATCTATGCCTGCTCTTGTGCTACAACAGTAGAGTTGAGTAGTTGGAGCAGACACT +TTGTGACTCTTAAAACCTAAAACATTTGTCAGGCTTACAAAAAGAGTTCTGCAGCTCGAC +CCTAAGTCCACATTTCTTTCTTTTTTCTTTTTTTTTTTTTTGAGATGGAGGTTACAGTGA +GCCGAGATCGCGCCACCGCACTCCAGCGTGGACGACAGAGTAAGACCCCATCTCAAAAAA +AAAAAAATGCTAGAACAGAGGCCCCCTAAAGATGGGGGAAGGATTCTGAAATAGACGGCC +GCAGAGGGCAGCAGTCAGCTAGATGCATCGCCCTGCCTTGTGGCTGGCCTGTGGCCTGGG +GGCCCTTCCTTCATCCCTCCACCAGTCCCTGCTGATGGCGAAATTGTGCTGACAGATGCT +GGAAGGAGGCACAGCTAGTCCTGTTTGCTCGAAGAGAGGGCTTTGAAGCCCTAGTGTTTC +CACCCTGGGTAGACAGTGAGATGGTTGTTTTGTTAGCAGGAGAGCACAATTCTACGCTGT +GAGTAAGAGCCTAAGAGGGCCTTTTGTTCATAGAAAACAATTAGATGACGGATTTTTGGC +ATCCTTATCTGGACTGCCTTTCTTTAGGAATAAACAGATGATACAGAGCAAAGTTTGTAA +ATCTCAAATGCAGCGGTTAACCTCTTTGAGGCTGGCCCACTGGGCTCCCAGGGGCAGCTT +CTAAGTGGGAAATGTTTCGATGGAATTCTGGTTACATAAGGAAGTTGCTTTGAAAATCTG +GGATAGTTTTCTATAATGGAATCATTCCCTTGTGTCTTTATTCACGATGAAGTGTAGAGT +GAAAGATGCCTCCACTGGGGGTATTGGTGCACGAGAAAAGCCACCTGTGTGACGTAAATT +CATTCTGTTTAGGCAAAGCTGGGACTGCCACATTGGCAATGTCAGAGAAGGTGCGGACCC +GGCTGGAGGAGCTGGATGACTTTGAGGAGGTGAGCAAGTCATTTGTGGAATACAGGGAGT +GGGAGAGCTTTTCCTTCCTCCTGCCAAGTGAGATCAACCTCGGTGGCTGCTCTTTGATTA +ATTCCTGGGCTGCGCATTGTGCTTGGTCCTCTCGAGGCAATGACTCCATCCAGGGAAGGG +TGCCAGTGTGCAGTTGGCCGAGCTCACGGAAGCCTGACTGGGGCTGCTTTTCTAGAGGCC +TCTTTTCTCATTGTGATGCCTGAGCAAGGCTGGGTCGCCTAGCAACAGTGTCTAATGGTA +AAAACCAACTGCAAGGCCAGGCGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGG +CCAAGGCGGGAGGATCACCTGAGGTCAGGAGTTCGAGACCAACCTGGCCAACATGGTGAA +ACCCTGACTCTACTAAAAATACAAAAATTAGCCAGGCGTGATGGTGGGTGCCTGTAATCC +CAGCTACTCGGGAGGCTGAGGCAGGAGAATTGCTTAAACCTGGGAGGCGGAGGTTGCAGT +GAGCCAAGATCATGCCACTGCACTCCAGCCTGGGCGAAAGAGCAAGACTTTGTCTAAAAA +AAATAACCCAACTGCAGTCACCTCCCTGAGAAGCAGCCTTATATGGAGCACAAAGACCTT +GCTTTGCAACAGACGCTGCTCAGGCTGGCTGGATATGGCCCACAGGAATCTTTTAATTGG +CCTACATGTACTTTGAAAAAAAAGTGAGTCTTTTGCCAACACTTAAACAGTGGTAAATGT +AACCAACAAATACAGAATTTCTTGAAAAAAAAAATCTTTGCCAGGCGCGGTGGCTCATGC +CTATAATCCCAGCACTTTAGGAGACCGAGGCAGGTGGATCTCCTGAGGTCAGGAGTTTGA +GACCAGCCTGGCCAACATGGTGAAACCCCGTCTCTACTAAAAATACAAAAATTAGCTGGG +CATGGTGGCGGATGCCTGTAATCCCAGCTACTCAGGAGGCTGAAGTAGGAGAATTGCTTG +AACCCAAGAGATGGAGGTTGAGATCGCTCTGTCACCCAGGCTGGAGTGCAGTGGTGCGAT +CTCAGCTCACTGCAACCTCTGCCTCCTAGGTTAAAGCAATTCTCCTGCCTCAGCCTCCCG +AGTAACTGGGATTACAGGCACGCGCCACCGTGCCCAGCTAATTTTTGTATTTTTAGGTGA +GAGGGTTTCACGATGTTGACCAGGCTGGTCTCAAACTCCTGACCTCAAGTGATCCACCCG +CCTCAGCCTCCCAATATGCTGGGATTACAGATGTGAGCCACCATGCCCAGCCTACTCTTA +TTTCTTTAATAAAGCGTTTTTCACTTTGAATTGTAGGAAATATACATATAAACCTTTGGT +TCCAGGTCTCATCATGTGTGTTTGCATGACCTTCACTCCTGTGAGTTGTGTGAAGAGCCT +CTTAACAATAGCCCAGGGTTAAGGAGCATTTACTGTGCGTCAGGGACCGTGCCAAGTCAT +TACCTACATGGTCATTTCATCCCCATGACGATCCCTTGCTCAGCTGCCGAGGGTTTTTGC +TATGGTTGTCTTTCTGTCCTGATTACTCTCTCCTTGGTCTAATTAACACCCCCACACTCT +GCAGTACCTGTACTCCCCTGAGAGTTTGTCTCAAGTATCACTCCTCCAGGAAGCCATTCC +TGATCCCCCCATCACAGTTTACAGTCCATTTCTTTGTTACCATATTTTTTCCAGTCTGAG +ATGTACCATTTCTCTCACATTTGAATATCTCTGAAATTGGGGTATATGTTCCTCAGTTGG +TTCCTGTCAGTGATCAGCATATTTTTCTTCCTTAGTAGCCCGTGAAACAGTTGCGCTTTT +TTCAATGGGCACCTCAGATCCAGTATATGTGTCCCCATAGAATTGTGTTTTCTCCTGAGC +ATTTATCTCAGTTTGAGTTAATATCCGTCTGTCTTCAGAATCTTAAGCTCCATTAGTGCT +GAAATACCCTGTCATGTCTTATTGCTTGGGAATCTTGAGCAAAAATGTCTTTGTATCTCG +ATCATCTAGTCCCATGTCCTGCACACAGGGGGCCCACAGTTGGTTGAATGAGGTAAGTCT +TGTTACCTCAATTCACAGATGAGGCTGTGAGAGGAAAATAGCTTACCCAGGGTCACACAG +CTACTTGGTGTCCAAGCTGGGAGGTGGCTTAGGTCTGACTTGCTTCCAAGGCCAGACTTT +CAACCCACAGCACTCTGTCCATCTTTGTCAGAAAACTCAAAAGAACCTCTTTGATTGCAA +ATTGCAAGGCAAAGCTGTCAATCCTGGCGGGGATATGAGGAAAATTTAGAGACCAAAACT +CAGCCAATACCTAGTATTCTTTATAAGGGTGTAGTCGAGCAATGTTTTTCCTGCTATGCC +TTCACCTTCTGCCTTCTCCCCACAGGGTTCCCAAAAGGAGCTGTTGAACTTGACTCAGCA +GGATTACGTGAACCGCATAGAGGAGCTCAACCAATCGCTGAAGGATGCCTGGGCCTCAGA +CCAGAAAGTGAAGGCTCTAAAAATAGTCATCCAGGTTAGCTCTAGTGATCCCCCACCCCC +ACCCAGAATTTCCTATGTAAAATTCCACTGTGAGACTTAGAGTTTTCAGGGGCCTACCTG +CAGGGTCTTACTCTTGTTTTCTCATCCCTTTCTTTTTCATATACTTCCTGTGAAAAGCCA +TGATTATGAATCTGTGTTTTTATGAGATGGCTAATCCCAGGGTTACCATGTGCAGCTGCA +CAGGTTGTGCACTGCACAACTCCAGGAAGCACTCTTCACCCTAGGTTACAGAACTGATGA +TACCCCATGTGTTGTGCAGTACATTAACCATGGTGCAACCCCTGACACATTTATGATTTG +TACACACTAAAGATTGAGCAACTTTCTTTCGGGATTCCTTGACCGCATTCGCTTGGTGTC +TTTGGGATTAATGACGTGTCCCTAATAAATGAATATTTCAGACATATTATGCATGCTTAT +GTGACAAGGAGAAGTTTACAGCGTTGGGAGAGGTACATACATTGAATCTTCTTTGTTGAT +GAATTTGTTAAGCCAGTGACAATTCTTGAACCACAAGAACAAGTACTATGTGGAAAACAG +CTTATATGTCTTGGTCCTAAAGATCCTGCTGTCTCAGCAAAATGTGCTCAGAAGCATATT +TGGAAAGGAATAATTCATTAAATTATCATTTTCAGAGCAGAGTCTACAAAGGATTTCTGA +ACTGCCATTTTAGTTCAAAAGGACAGATCCCATTCTCATTCCATGTTATGATAATGTGAC +ATTTGTTTTCTCACCTGTTCTTTTGAAAGACAGGAGAGTCCGGGAGTCTTCACACTGGAC +ACATGAAGTCTTTTAAGATGACTCCTTGTATAGTACGGGTGATTTCTTTGGTATTTCATG +ATGGGAGGCAAACCCACGCCCGTTTCTCTTCAATCACTGTTGTTAGTTTACAGAGTAAAT +AGTCCCGAAGGCCAGGCCTCTCATCCTGGAAGCCCGTGGAGAGGGTTGCTTGCTGAGTGT +CTCGAGTGAGAAACTATCTGAACTAACAAGTACTTCTTCACAATATTTGCATTGGCAGCA +TCTCTCCGTAGATTATTGTAGTTTAGAACTGTGTCTTCTAAGAGGTTTACATCTGGGGGA +GATTTGATTCATGTCTTCACAAACAAAATAATCATTAAGTGTGTTTCATCAACTCCACAT +CTGGCTAATAGTAACGATTCAACAATACATTAAGGACTGCCTTCTTTATCCAAAAGACAT +AGTCAAGGCTGGGCACAGTGGCTCACATCTGTAATCCCAGCATGTTGGGAGGCTGAGGCG +GGTGGATCACTTGAGTCCAGGAGTTTGAGACCAGCCTGGCCAACATGGTGAAACCCATCT +CTACTAAAAATACAAAAATTAGCCAGGCTAATTTGCTATACGGTAAAGTTTTTTTGTGTG +TGTTGGGGGGGTACCCAGTGGCTGCTTTACTAAGGCATATTTTACATATCATAAAGTCCA +CCCATTATAAGTGTGTAATTCATTGATTTTTTTTTACTTAACTTATAGAGTTGTGCAACT +AACACGCAATCTAGTTTTAAAACATTTTTATACCTCCCCAGATTCCCCCGAGCCTGTCTG +TAATCAAACCCCACTGCCATACCCAACCCCAGAAAACCACAAGTCTGTTTTCTGCCTTTA +TAAATCTACCTTTCCTGGATATTTCATATACATGGGATTATTCAATAGATAATCTTTTGG +ATCTGGCTTCTCTCACATAGTGTAATGTGCCTTTTTAATTGATAGATAATAATTCTACAT +ATTTATGGGGTACAGAGTGATATTTTGATACATGTATCCCGTGTGTAATGATCAAATCCA +AGTAATTAGCATATTCATCACCTCACACGTCTCTGATTTCTTTGTGTTGGGAACATTCAA +AATCTTCTCCTCTAGCTATTTAAAAATACACAATAAGCTGGGCCTCGTGGCACACCCCTG +TAATCCCAGTTACTTGGGAGGCTGAGGCACGAGAATTGCGTGAACATGGGAGGTGGAGGT +TGCAGTGAGCCGAGATCGCACTACACCACTCCAGCCTGGGTGACAGAGTGAGATTGTCTC +AAAAAAAAAAAAAGGAAAACAGAAAGAAAAGAAAATACACAATAAATTTTGGACTATAGT +CACCCTAGGTGCTATTGAACACTAGAACTTATTCCTCATATGTAGCTGTAATTTTGTACC +TGTTAACCAACCTCTTTGTTCTCCCCTTGCCCCTACCCTTCCCAGCCTCTAGTCGTCGCT +GTTCTACTCTCCACTTCTATGAGCTCAACTTTCATAGCTCCCACATATGAGTGAGGACAT +GCAGTATGTATCTTTCTGTGCCTATTTCACTTAACATGATGGCTTCCAGGGTCATTCGTG +TTGCTGTGAATTACAGAGTTTCATTTTTTTATGGCCAAATAATATTCCTGTGTGTGTACC +ATGTTTTCTTTATCCATTCATCCATTTATATACATTTAGATTGATTTCATATCTTAGCTA +TTGTGAATAGTGCTGCAGTAAACATGGTACTGCTGGTATTTCTTTGATATACTGATTTTC +TTTTCTTTAGATGATAACCTAGTTGTGGGATTGCTACATCATATGGTAGTTCTATTTTTA +GTTTTTTGAGAAATTTCCATACTGTTTTCTAGAATTGTTACACTAATTTGCATTTCCACC +CATAGTGTGTAAGAGTTCCCTTTTCGGCTGGGTGTGGTGGCTCACGCCTGTAATCCCAGC +ACTTTGGGAGGCTGAGGCAGGTGGATCACCTGAGGTCAGGAGTTCGAGACCAGCCTGGCC +AACATGGTAAAACCCCATCTCTACTGAAAATACAAAAATTAGCTGGGCATGGTGGCAGGT +GCCTGTAATCTCAGCTACTTGGGAAGCTGAGGCAGGAGAATCGCTTGAACCCAGGAGGCA +GAGGTTGCAGTGAGCCAAGATTGCACCATTGCACTCCAACATGGGCAACAAGAGCAAAAC +TCTGTCTCAAAAAAAAAAAAAAAAAGAGTTTCCTTTTCTCTGTATTCTTATCAGCATTTT +TTTTCTTTCTTTTTGTTTTTTTTTATTAAGAGATGAGGTTGCCCAGGCTGGAGTGCAGTG +ACTAGTCACAGGCATGATCATTCTGCATTACAGCCTAGAAGTCCCAGACTCAAGTGATCC +TCCCACCTCAGCCTCCCAAGTAGCTGGGACTATAGGCACATACCACCATGCCCAGCCTAT +TTTTGTCTTTTTGATAGTAGTCATTTTCATGTGGTTTTCATTTGATGATTCCCCTGATGA +TGAGTGATGCTGAGCATATTTTCACATACTTGTTGGCTAATTTGTGTATCATCTTTTGAG +AAATGTCTCTTCAGCTCTTTTGTCCATTTTTTAATTGGATTATTTTCTTTAGCATAATAT +GTTTGAGGTTCATCCACATCATATTACATGTGGGTAGTTCGTTCCTTTTTACTGCTGAAT +CGTATTCTAATGTGTGGTTATCTTAACAAGTTGATGGGCATTTGGGTTGTTCCCACTCTC +TGGCTGTTATGAATAATGCTGCTCTGCACATTTGCGTACAATTATTTGCGTGGACTTACA +TTTTTATTACTCTTAGGTAAAATTTTAGGAATGGAATTGCTGGGTCATATGGTAAGTTAG +GATTAACTTGATGAGAAACTGCCAAACTATATTCCAGATGGCTGCACCATTTACCTGAGG +GTTCTAATTCCTCCACATCTTCTCTGACACTCGGTATTGTCCATCTTTTCTTCTGTTTTC +TTTTTTCTTTTTTTTTTTTTTTTTTGAGACAGGGTCTCTGTCACCCAGGCTGGAGTGCAG +TGGTGTAATCATAGCTCACTCCAGCCTCAAACTCTGGCCTCAAGCGATCCTCCCGCCTCA +GCCTTCTGAGTAGCTGGGACTACAATTGGCCACAACCATGCCCAGTTTATTTAAAATTTT +TTTTTTGTAGAGACAGGGCCATGCTGTGTTGCTCAGTCTGGTCTTGAACTCCTGGCTTCA +AGTGATCTTCCCATCTCAGCCTCCCAAAGTGCTGGGATTACAGGTCTGAGCCATCACACC +TGGCCTATCAGTTTTGTTATAACCCTCCTACTATCCTAGTGGGTTTGAAGTGGTACCTCA +TTGTGGTTTTAATTTGTATATCCCTAACAGTGATGTTGAGCATCTTTGTACACGCTTATT +GGCCATTTGTATATCTATAGTGAAATGTCTATTCAATGCCTGCCCATTTAAAAATTGTGT +TATTTGGTTGAGTTGTAACAATTTTTTTTTCCTTGGGAGACAAGGTCTTGCTCTATGACT +CCAGATGGAGTGCAGTGGTGCCATCACAGCTCAATATAGCCTTGACCTCCCGGGTTCAAG +TGATCCTCCCACCTCAGCCTCCCCAGTAGCTAGGAGTATAGACATATGCTGCCACACCCG +GCTAATTTTTAAATTTTTTGTAGAAACGGAGGGTTTTACTTTGTCATGCAGGCTAGTCTC +AAACTCCTGTGCTCAAGCGATCCTTTCATCTTGGCCTCCCAAAGTGCTAGGATTACAGGC +ATGAGCCAGTGCACCTGGCCAGTTGTAACAATTCTTTATATATTTTTGACACTATTTCTT +TGTCAAGTATAGGATCTCCTACTCTGTGGCTTGTCTTTTTGTTTTCATAATTGTGTCTTT +GAAGTGTGGAAGTATGTATGTATGTATGTGTATATTTATTTATTTATTTATTTATTTGAG +ACAGAGTTTCGCTCTCGTTGCCCAGGCTGGAGTGCAGTGGCATGATCTCAGCTCACTGCA +ACCTCCGCTTCCTGGGTTCCACCGATTCTCGTACCTCAGCCTCCTGAGTAGCTGGGATTA +CAGGAGCCTGCTATCACGCCCAGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTTTGCC +ATGTTGGCCAGGCTGGTCTCGAACTCCTAACCTCAAGTGATCCACCTGCCTCGGCCTCCC +AAAGTGCCAGGATTACAGGCGTGAGCCACCGTGCCCAGTCAGAAGTTTTTACTTTCAGCT +CCATTCTCAATTTTCTCATTTTAGCTTATGCTTTTGTAGTTGTATCTAAGAACTCTTTGC +CTAGCTCAAGGTCATGAAGATTTTTTTGTTTTCTTCTAGAAGTGTTATAATTTTAGCACT +TACATTTAGGTCAATGGTTCATTTTGAATTACTTTTTATATATCCTATAAGGTAAGGATC +TAAATAATTTTTTTGCATGTGGAGCTACAGTTGTCTCAGCAACGTTTGTTGAAAAGACTA +TTGTATTAGTCCATTCTTGCATTGCTATAAAGAACTACCTGAGACTGGGTAATTTATGAA +GAAAAGAGGTGTAATTGACTCACAGTTCTGCAGGCTGTATAGGAAGCATGGCTGCGGAGT +CCTCAGGAAACTTAAAATCGTGGCAGAAGGCAAAGGGGAAGCAGGTACATCTTTCCATAG +CAGAGCAGGAGAGAGAAAGAGAGAGAGAGAGAGAGAACAGGGAGGTGACACAGGTTTTCA +GACAACCAGATCTCATGAGAACTGTCTGACAGGAACAGCAAGGGGGAAGTCTGCCCTCAT +GGTTCAGTTACCTCCCACCAGCCCTTTCCTCCAACACTGGGGATTACAATTCGACATGAG +ATTTGGGTGGGAACACAGAGCCAAACCATGTTAACTATGTTTTTCTCTACTGAGATCTTG +GCACTTTTGTTAAAAATCAATTGACCAAGGCTGGGCGTGGTGGCTCATGCCTGTAATCCC +AGCACTTTGGGAGGCTGAGGTGGGCGGATCAGCTGAGGTCGGGAGTTTAAGACCAGCCTG +ACCAACATGGAGAAACCCTGTCTCTACTAAAAATACAGAATTAGCTGTGTGTGGTGGTGC +ATGCCTGAAATCCCAGCTACTTGATACTCAAGGTTGAGGCAGGAGAATCACTTGAACCCA +GGAGGCGGAGGTTGCGGTGAGCCAAGATCGTGCCATTGCACTCCAGCCTGGGCAACAAGA +GTGAAACTCCGTCTCAAAAAAAAAAAAAAAAATTAATTGACCACTGGTGGCAAATTCAGA +CTACTTAAAAAACAAAAAAACAAAAATCAATCGACCATAAATGTAAGAGTTTATTTCTGG +ACTCTCACTGTCATTCTGTTGATCCATAAGTCAATCCTTATGCCAGTTCCACATTGTCTT +TTTTTTTTTTTTTTTTTTGAGACACAGTCTTGCTCTGTCACCAAGGCTGGAGTGCAGTGG +CGTGATCTCTGCTCACTGCAACCTCTGCCTCTCAGGTTCAAGCGATTTTCATACCTCAGC +CTCCCCAGTAGCTGGGATTATAGGTGTGCACCACCACACCTAGCTAATTTTTGTATTTTT +AGTAGAGGTGGGGTTTCACCATGTTGGCCAGGGTGGTCTCGAACTCCTGACCTCGAGTGA +TCCACCCACCTCGGCCTCCCAAAGTGCTGGGATTAAAGGCATGAGCCACTGCGCCTGGCC +AGTTCCACATTGTTTTGATTACTATGGCATTATAGCAAGTTTGAAACTGGGTAATATAAG +TATGTATGTATGTATGTATGTATGTATGTATTTATTTATTGAGACAGAGTCTTGCTCTGT +TGTCCAGGCTGGAGTGCAGTGGCATCATCTTGGCTCGGCTCACTGAAACCTTCACCTCCC +AGATTCAAGCGATTCTCCCACCTCAGCCTCCCGAGTAGCTTGGATTACGGGCATCTGCCA +CCATGCCCGGCTGATTTTTGTATTTTTAGTAGAGATGGGGTTTCACCGTGTTGGCCAGGC +TGGTCTCAATTCAAACTCCTGACCTCAGGTGATCCACCCACCTTGCCCCCCGCAAAGTGC +TGGGATTAAGGCATGAGCCACCACGCCTGGCCTGGGTGGTGTAAGTCTTTTAACTTTTTT +TTTCTTCTTCTTTTTTTAAATTATTTTCACTGTTCTGGGCCCTTTGCATTTCTGTATGAA +TTTTAGGATCAGCTTGTCAATTTTTACAAAATAAAAAAAACCTTCTGGGATTCTGACAGG +TATTGCATTGAGTATGAAATCATTTTCTGATGCATAAATTTTGCCATCTGTTGATGAGCA +TCTGGCTCTGTTCTTTTTTCACTACATGGACAATGTCACTGTGAGCACGTTTGGTCACGT +CTGCTGGTGCCCATGTAAAGCTTTTCTCTAGATAAGAGCCTATACCTAAGAGTAGAACTG +CTCTGTGCCTCTTCAGCTTTTCCAGATAATGCTAAGTTATTTTCCATAGTAGCTGTGCCA +GCATACGCTTGTAGTAGTATGTGGGCGTGTGAGAGTCTGTGCTATTCAACATTCTACCAC +CATTTGGTATGAGCAGATTTTCTATTTTAATTTTTCCAGTCATATTTTCTTGTGGTTTTA +ATTTGCAGTTCCTCGATTACTAATAAAAATGAGCATCTTTTCACATATTTATAGGCCTTT +GGGGTTTCCTTTTCTGTAAAATGACCTTTGCTGATTTCTTTTGCCCATTTTTCCATTTTG +TTATCTGTGTTTTTCGTACTGAGTTTTGCAATTTTTAAGATGTATTCTGGATAGTAATGG +TCTACTTCTTTCCTTCCTACTCAGGTCATCTTTGAATGTATGCATTTGTTGTGGCTATTC +AAATTTTTTTAACCTTTTTTCTGAGACAGATTCTTGCTCTGTCTTCCAGACTGGAGTGCA +GTGGGGCGGTCTCGGCTCACTGCAACTTCTGCTTCCCTCGCTCAAGTGATTCTCCCACCT +CAGCCTCCTGAGTAGTTAGGGCTACAGGCACACACCACCATGCCTGGATAATTTTTGTAT +TTTTTGTAGAAACTGGGGTCTCACTACATTGCCCAAGCTGGTCTTAAACTCCTGGGCCCA +GGCGATCTTCCTGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCATGCC +CAGCTGGGATTTGTATTGTTAACACATACCTGGGTTACCTGATTCTTATCAGACAAGTTT +AGGAAGCGGCACCAAAGCTTTAAAAACTGTGGCATCTTCAAAACAGTAATTTAAAAAGTA +ACTTCAATTTATAAGATCATTATAGCTTTAACTTTGGATTAAAAACAAAATCTTATTCCT +GTTGTCCTTTATAAAATATATGTTCTATGAAACCAGCTTGGGAGAAAATCAATGCACAGA +TGTTTGGGAAGCCCCAGCTGTGTTTAATTTGAAATCCTCTGTTTAAATTCTCTCTCTCTC +ACCTCACCAGTGGGCAGTAACTCATCTCTGAGAGACTGTCCAAGCCCAGCTCTGGGTAGA +ACTCAGAGATGTCACATCCCTAGGAACCGAGAACTGTGTATTGTAAACAGTCTCTGAGAT +TTGGAGTTGTTAGCTTTTTCCAGCCTTGAAATCTCATGGGGGCAGCTGTTTAAGTTGGAA +CTCTCACAAAGGGCATATGAAAATCGCAGAGCGAGGTGTCAGGAAATGGAATTCCACATA +CATCCAGTTGCCACGTTTGGTGTCAGCACTATTGTTTTTACAGCTTACATTCCCGCCCCG +CCCCCCCCCCCCCCCCCACAAATAACATTTGGGCTGTAAGGGGATGTTTCGCAAATCAGA +CACGTTGTTTACTTTTAGGCCTGTAATGCTATGGAGAAACTTGGTGACTCTAACAATTTA +GATGTTGGGTAACAACACCAAACTGAAAACACATGTCAACCTATCTCTTGACATGGTGAA +CGTTCTCACCATTCTCTGCATATTGGAATTGCATATTAAATAATCCTTTCTAAATGTCTG +AACATCTTTTTTTTAATTTTTAAATGACATTTTTCTTTCTGAGGGTCAACCATTGAGGTG +ATGAAGTGTGGCAGTTATTTAATTCCTTATGCTGACTTTTGAATTTGTAAAGTCTTCAGG +GCATGGCATTAAATTTAGTTCTTCAAAGTAGAAAGAGCTTTTCTGTTTCTGATGATAAAA +GATAATCAAAGGTGTTTGGGGCCACATTGTGTGACTGCGGTCTTCCATTAAAAGTCCTGA +ACGCTAAATAGCAGACGAGTACTCAAAAAAAGAGTTCTGAACATGTTGGCCGGGTGCAGT +GGCTCATACCTGTATTTCCAGCACTTTGGGAGGCTGAGGTGGGAGGATTGCTTGAGGTCA +GGAGTTCAAGACCAGCCTGAGCAACATAGTGAGAACCTGCCTCTACATAAAATTAAAGAA +AAAAAATTAGCCAACCATGGTGGTACATACCTGTAGTCCCAGCTACTCGGGAGGCTGAGG +CAGGAGGATTGCTTGAGCCCAGGAGTTCATTGCTGCAGTAAGCTATGATTGCACCAATGC +ACTCCAGCCCGAGCGACAGAGCAAGACCTTATCTCTAATAAAATAATAATAAAATTTAAA +AAAATTAAATAGTCCTGAACATGGCTGTGACCCTTTGGCATGAATGAGAATGTAGAATTC +AGCAATTCCCCGCAAAGCTGAAATGTTTTCAGCATTGAAGGTCATATTTCCAGAGTAACA +TGTATTCACTGAAGCTTATGTTCCTTTTGGGGGGAATTTGGGACTGAGTATAAATAATCA +GTGTGAGTTTATGAAGCCTTGGGGATTTACTTATGGGGTCATTTCTTAGAAAAGAATGTT +TAAGGATGCTGATCACCCTGAAATCAACAGAAGAAGCCAGTCTGCAAAGCAATTGAACAA +AGATGGGGCCACAGATGAGGACTGTGATGAGAGAGATGTCATTCACTTCTCTCAGTGATT +TTGAGTGCTTCCTGGTTCAGTATACAAGCAGGATCCTTTTGGATAAGGCTTTCCTGAAGA +AGGTGATAGTGTATTTTCTTAAGAGACTGTTATGGGCCGGGTGCGGTGGCTCACGCCTGT +AATTCCAGCACTTTGGGAGGCTGAGGTGGGAGGATCACTTGAGGTTGGGAGTTTAAGGCC +AACCTGGGCAACATAGCGAGACCCCATCTCTACAAAAAAAAAAAAGGAAGGGAAAACAAA +GAAGAGGTTCTGTTGTAAGCAGAGTCCGGCTCTCTCTGTGAAAAGCACAGTGGTTTAGCT +TGTCATTGTATGCTCAGCACCTCGCACAGGCCTTGGCACATAGTAAGTATCTCAACTTGT +ATATAGAAACCATTAATTTTTCAGATCTGGAGTGTCCTACCCATACCAGACATGCCAGAG +TGAATTTTCTCTTTTTTTCTCTTTTTTTAGTGTTCAAAGCTTCTTTCAGACACCAGTGTT +ATTCAGTTCTACCCAAGCAAATTTGTCCTTATCACCGACATACTTGATACATTTGGTAAG +TACCTGTCATATGCATCTTAGATCTAGGAAATGTGTTCGTTTTGTCAAGAATTGGGTGGT +AGAGTTACTGTAAATTAGGTTCTGCTGTGGTTTAAGTTATTAAGTAAGTCATGGGAGAGA +TCAAACCGTTCCCCCCCACGCCCATTAATAAGGGCGCTATTTTTGAAACATTCTAAAATT +TCTAAAATTTTATTTTTTCTTCTTTTTTTTTTTGAGTCAGGGTCTTGCTCTGTTATCCAG +ACTGGAGGGCAGTGGCGCAGTCATGGCTCACTGCAGCCTCAAACCCCTGGGCTCAAGCCG +TCTTCCTGCCTCAGCCTCCTGAGTAGCTGGGGCTACAGGCTCATGCCACCGTGCCCAGCT +AAGTTTTTTTTTTTTTTTTTGGTAGAGACAGAGTCTCGCAGTGTTGCCCAGGCTGCTCTC +AAACTCCTAGCCTCAAGTGATCCTCCTGCCTTAGCCTCCCAAAGTGCTGGAATTACAGGC +ATGAGCCACCATGCCTGGCCTGTTTTTCCTAATCTTGTGATAGACTAGTAAAGTGAATGA +GTGAAGCAGGGCAGGCTGGGGGCACTAAGCAGCATGGGTCCCTTGCCGTCTCACAGGCAC +CTGAAACTGAACTTGGCATCTGTTCCCAGCCCTTTCTCTTTTCCCACTGAGTTTCTGTCT +CCAGGAATGGCACCACCATGTACCCAGTTGCCTGAGCTGGGAATCTGAGCATCTTCCCCC +ACATGCCCATGTCCAGTCACCAGATTCTTCGGTTCAGCCTCCTAAAGCTCTCCCCAGCAT +GTCTATTTTTTTCTTTCTTCACTGTTAAAATTTTTTTTTTTTTTTTTGGAGATAAAGTCT +CTGTCACTCAGGCTAGAGTACAGTGGCGTGATGTTGGCTCACTGCAACCTCTGCCTCCGG +GGTTCAAGTGATTCTCCTCCCTCAGCCTCACCAGTAGCTGGGATTACAGGCACGCACCAC +CACGCCTAGCTAGTTTTTGTATTTTTAGTAGAGATGGGATTTCACCATGTTGGCTAGGCT +GGTCTCAAACTCCTGACCTCAAGTGATCTGCCCTCCTCGGCCTCCCTAAGTGCTAGGATG +ACAGGCATGAGCCACTGTGCCCAGCCTCACTGTTAAAATTTTAATCCTAGCCACAGTCCT +CTCCCACCTGGATAGCTTCCTGCATCACTGTGGCTGCCCCTAGTCCCACACACCACCTCA +CAGGTAGAGAGACCTTTTGGAGCCAGGTAGAAAGGTTTAGACTGAAGAGAATAACCTGGA +GGAGCAGGAGGCCCCTGTGCTGCTTGGCAGTGGTTGGTTAGGCCAGAACATCGTGCCATT +AGCAGTTTGCTCAAACCATGCAGCCCTCTAAGCTGTATATGATGTGCCCCACAGCAAGGC +ACCCCACCAGAACCAGGAAATAGGGGCGCCTTCTGAGAGCTGAACACGTGGAAGATCAGA +ACAGAGACATTCACTGTCTTACAGGGACTAATGGGCTCCCAACCCAGCAAATCTTATCTG +TAAACCCATCGAAAGATACAATGTGTCAGAAAGCAGACTATCAATCTGAGAGACTCATTC +ATTTCTGTGCATCCCAGTCCTGTCCAAGAGACCGGAGGCCTGAGTGCGCTAGCTAAAACA +AGTGACAAGAAAGCTAACTAACCTTGAAAAAGTGGGTCTTTATTGGCTTATGCTGAAAAG +TCCAGGGGTAGTTTGGCTTCAGGTGCAGCTGGATCCAGGAACCCAAACAGTGTCATTAAG +ACCTTGCCCTTGGGCCGGGCATGGTGGCTCATCACACTTGTAATCCCAACACTTTGGGAG +GCCGAGGTGGGTGGATCATCTGCAGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGTGA +AACCCCGTCTCTACTAAAAATACAAAAATTAGCTGGGTGTTGTGGTGCACACCTGTAGTC +CCAGCTACTTGGGAGGCTGAGGCAGGAGAATTGTTTGAACCCAGGAGGTGGAGATTGCAG +TGGGCCAAGATCACGCCACTGCACTCCAGCCTGGGCGACAGGGCGAGACTCCGTCTCCAA +AAAAAAAAAAGAAAAGAGAAAAAAAAAGACCTTGCCCTTGGTTGGGTGCATTCTCGAGCT +TCACAAGCTGTCCTCAGCTTCTGCTAGCTTTATTGCTAGTGGTCCCAGGGCATGGAAAGA +GCTACTTTCTCCAAGCATTCCCACAGAAGTTTCAGAATCCCATCTTATTGGCCTGGCTTG +GATCACATGTCAGTCCCTGAGCCAGTTGTGTTATCTGGGGGATGAAATGCACTGATTATC +CAGGCCTGGGTCACCCCAAAACTAAAAGAGTGATACAGTTAGCAGAAGAAAGGGGAGTGG +ATGCTACCTGGGCAAAAAGAAGAGATGTCCCAGCTGACAGATGAGCCCTGATGGGTTCAG +ATGGCCCGGAGAGGTGGTATCAGGCTCTCTGCAGGCCACTAGGGAGGTGTCAGCAAACAG +AAGGGATAAAAATCCTTGCCTTGGCTAGGCACAGTGGCTCACGCCTATAATCCTACCACT +TTTGGAGGCTGAGGTGGTTGGATCACTTCAGGTCAGGAGTGCGAGACCAGACTGGCTAAC +ATGGTGAAACCCCATCTCTACTAAAAATATAAAAATTAGCCAGGCTTGGTGGCAGGCACC +TGTAATTCCAGCTACTTGGGAGGATGAAGCAGGAGAATCGCTTGAACCCGGGAGGTGGAA +GTTGCAGCGAGCTGAGATCGCGCTGCTGCACTCCAGCCTGTGCCACAGAGCTGAGATTTC +GTCTCAAAAAAAAAAAAAAAAAAAAAAAAAAAGAAGAGAAAAAAAATCCTCGCCTTTGTG +GTGCTTATGTTTCCAAAAAAGAGAATTTACAAAACAATTAAGTCAACCCAATTGTATGTT +AGACAATGATCCATGCTATGGAGAAAACCAGAGTGGGGTGAGGGGGTGAAGAGGAATGGA +GGGAATTAGGTGAGGGGGTAGGGGTGCAAGTTTAAGTAAGGTGCTCAGAGGAAGCCTCGT +TGAGAGGTTACCTGAGCAGGTGCTTGAAGGCGGTGAGAGGGGAGAGGTGAGCCCTCTGGG +TCTGTGGGGTGGAGGCCAGGGGCAGAAGAGGCCAAGGAACAGCTTGTGCGGAGATCCTGG +GGTGGGAGCATTGGGAGCATGCCAGGCTGGCCTGAGAACCAAGGAGGCCAAGAGAGAGGC +GATGAGATGAGCCCGGGAGAGGGGCAGAAACTGACATGGTCAGAGATCATGGTGGCCTTG +GGGGCCACTGGGAGGACTTGGGCTTTGACTCTGACTCTGAGGACAGGAGGGGCCACCAGA +GGGTGTTGAGCAGAGGAGGGAGGTGATCCCACGTGGGATTTAACAGGCTCCGTGTTGAGA +CTAGACTGTAGGGCGGGGGTAGAGCCCGGAGCCTGTGGCAGCACTTGCGGTGAGAGGCAG +GGGTGGCTTGGCCCCGGGAGGCGGTGGAGATGGTGAGGAGAGACCCAGGATGGATGAGGG +CTTTAGGTTCTCAGGTTAGATGTCAAATCATACACTGCTGGTCCTTGACGTGTCCATGCA +CACAGCTTACCTTCGGCGAGTGTGAGGCCCTCATTGGTGGGGAGAGGCTGGTGGCTGTGT +CTGGCTCCCCTGGCAGTCTCATTCCTCCCGTGAATTAACCTCTTGGCCGTCTGGTTCCCT +CGCCCGCCTCTCCTAAGTTTCTTTTGTATGAGTCAGCTTTCCTGAGCAAGATTAACTCTG +AGACACTGATTAGCTCTATCCTGCAAGCCTGGCCAGACCCAGACAGCTCACTCACCTTGC +AAGAACTCTGGGCAGCCACTCTGCCAGCTCCTGCCAGCAGCACTCCAGCCCCGTCCTGTA +CTCCCCGGGCTGTAGTGCAGATGCTGCTGTCCTTGTTGCGTCCCAGAAAACAGCTGGGCT +GGGAGTTGGGAACAGCAGTGGTAAACCTTCAACAGATGATGACCTTGGACAGACTGTTTA +GGTGCTTTATAGATATTAAGTCCCGGCCAGGCGCAGTGGTTCATGCCTGTAATCCCAGCA +CTTTGGGAGACCAAGGTGGGTGGACCACAAGGTCAGGAGTTCAAGACCAGCCTGGCCAAT +ATGGTGAAACCTCGTCTCTACTAAAAATACAAAAATTAGCCGGGCATGGTGGTGGGCACC +TGTAGTCCCAGCTACTCGGGAAGCTGAGGCAGGAGAAAAAAAAAGATATTAAGTCCCATA +ATCTGCATAACAGCCCTATGAGATGGGTCTGGTTGTTGTCCCCATTTTATAGATGAGGAA +CCTGAGGCTTGGAGAAGGAAAGTAGCTTGCCCAGGGTCACCATCATAGTGAATTGCAGAG +CTGAGGCTCAACTAGCTCTCTGCAGTCAAAGCACCTACTTTATTTCTCTTTATACATTGC +TTATGGGGGAATGCATATACCATTTTTTTTTTTGAGACAGGGTCTCACTTCATTGCCCAG +GCCACAGTGCAATGGGGTGATCATGGCTCACTGCAGCCTTGATCTCCTTGACCCAAAGGA +TCCTCTTGTCTCAGTCTCCCAAGTAACTGGGACCACAGGTGTGTGCCACCATGCCCAGCG +AATTTTTTTTTTTTTTTTAGCAATGGGATCTCACTGTGTGGCCCAAGCTGGTCTCAAACT +CCTGGAGTCAAGCCATCCTCCCACCTTGGCCTCCCAAAGTGCTGGGATTATAGGCATGAG +TCACTGCACCTGGCCTAAATGCATGTACATTTAACCCAACAGTTTCACCTCTGGGAATCT +ATCCCACCTGTAATAGCAAACTATAAGAAGCAACTCAAGTGGCCATCAATAGGAGCTAGC +TCAATAAATTATGGTGTGTCTGTATAGTGGAGTACTAGTGGCTCTGTGAAATGAAAAGGC +TGGGCATGGTGGCTCACACTTGTAATCCCAGCACTTTGGGAGGCCAAGGCGGGCAGATCA +CTTTGAGCTTAGGAATTCGAGACCAGCCTGGGCAACATGGTGAAACCCGTCTTTACTAAA +AATACAAAAATTAGCTGTGCGAGGTGGTACGCGCCTGTAATCCCAGCTACTCGGGAGGCT +TAGGTGGGGGAATTGCTTGAACCCAGGAGGCAGAGGTTGCAGTGAACTGAGATCAAGCCA +CTGCACTCCATTCTGGGTGATAAAGTGAGACTCTATCTCAGAAAAACAATCAAACCAACA +ACAACAACAACAAAACAACAACAAAGAAGGGAAGGAAAGGGCTGGGCATGGTGACTCACA +CCTGTAATCCCATAATCCCAGCACTTTGGGAGGCTGAGGCAGGAGGATAACTTGAGTCCA +GGAGTTCAAGACCATCCTGGGCAGCATAGCAAAACCCCATCTCTACAAAACATTTAAAAA +AAATAGCTAGGTTTGGTGGTACAAGCCTATAGTCCCAGCTACTTAGGAGGCAGAGGCAGG +CAGATTCCTTGAGCCCAAGAAGTTTGAGACTGCAGTGAGCTATGATGGTACCACTGCACC +CTAGCAAAAGTAAGACCCTGTCTCAAAAAGAAGAAAAAAAAAAAAAGAAAGGAGGAAAAT +GTAGACTACATGTTGGTATTCACTTGTGTCTCCCTAAGGAGACATTAAAATGATAGCCAA +GAAACCGATAGAAATGGTTTCTCTCAGAGGGTGTGCAGGGCAGTGAGGTGGATGGGATGG +GCCAGGAGAGAAACTGCGCTCGGTACCTTCTGCAGCTTTTTTGAATTTTGAACCAAGGGA +ATGTTTTACCTATTCAAAACCAAACATTCACACAGAGTAGCTGCTTTCAGCACTTCCCAA +GGTCCCTGTCCTTCCTCTCCACTTCAGAATGGTGTTCCCACGGTGCTGTTGTTTAAGTCT +ATTGTGAATAATATTCCTCAGGACTGTTGAGGCAGCCTGCATGGACAGATGCTCAAAGAG +TCTTTATTAAGGTTTGGGGCTAATGAGTGTTCACTTTATAAAAAAGGAGTGAAACCCTGA +CTTGCTTGGTGGAAATGTGGAGTCCTGAGCTCCATTTTTCTGCACATGGTCATTACTCTG +CTCTAAAAGAAGATGCATGACAGTATAGGGACAGGTGTTTCATGGTTGTTGACATCATTG +ACAAGAGGGTCAGAGCATCTTGCTGTGCCAGGGATGCAGGCTAAGGCCCCAGCATCCACA +GAGACTGGCATGCACAGTGGGAAGACGTGTGCCTGGTTTCTGCTGGGATTTCACTGGAGG +CATTGGGTACAGAGGTGGGCTTCTGGCTTCAGTGCCTGCGTCTCCTGTTTCAGGGTTGTG +TGAACTTGAGCCTCAGTTTCTCCACCTGTAGAATGGGGCTATCGTAGACCCTGCCTCTAA +GGGTTTCTGGAGAGGATTAAATGAGAGGATTCATAGGAAGTATAATGTCTTTCCTTTTCT +AAGAGCTTGCTGGCAGGATTAAAGTAAATGACCTTGAATAGTGCTTGGCACAAAGTAAGT +GCTCAGAAAATGCTAGCTGTTACCACTGTTATTATTTATCTCTTTTAGTGTCTTTGATTT +GTAAGAAAGCAAATCAAGACAGGAAATAAATCTAGGATCAAGTGTTATTTCTCAAAATAG +TTGTCTACTAGCTTAATAGACAAATCACTTTTTTCAGTAAAACTAATTTTGTAGTTAAAA +GATCCTTAAAATATGAAAGTGAGGCCCAGTACAGTGGCTCATATCTGTAATCCCAGCACT +TTGGGAAGCCAGTGCAGAAGGATTGCTTGAGCCCAGGAGTTCAAGACCAGCCTGAGCAAT +ATGGTGAGACCTCGTCTCTACGAAAAATTTAAAAGTTAGCCAGGCAAGGTGGTGTGCGCC +TGTGGTCCCAGCTACTCAGGAGGCAGAGGTGGGAGGAGCCCCTGAGCCCAGGAAGTTGAG +GCTGCAGTGAGCTGTGATTGCTCCACTGCACTCCAGCCTGGGTGACAGAGCAAGATTCTG +TCTCTTAAAAAAAAAAAAGTGAAAAAGAATGTGGAGATGAAATTTTTTTTAAAAAAAAGA +AAGCTAGTTTTAGAGGGATGGCAACTTTCGTGTAGGAAATAAAGGTGTTTTGTGCTGGGT +TCATTCTGTGCACCATGGGAGGTGAGAAGTTATGCAGCCACCTAGTGTGGTTTGCTGTGT +GATGGTCCGAGGTAACATTGCATGCATCCCTAATGCCAGGGTTCTGGGGTCATCACAAGG +GAGGCCTCTCTCTACACGAGGTGTGGCGCTATAGGGAACCCAGAGCCGCTGATAAGGAAA +GCTCGTTCTGCCAGGAGGAAAAAGGCAGGTGGCTTTGAGAACTGGGGCTTGTTCTCTAAG +GCCTTCCAGGGGCTTCTAAATGGAGCCAGTGGTTTGGAGCAGTGCTTCTCATACTCAGCT +GCACATTGAAATCACCTGGGCAGCTTTACAAACACCCACAAAGTCCCAGCTGCATCCAGA +CCATTTAGAAGAGGACCTCTGAGGATGGACACAGACATCCACATATTTTCAATAGTCCCA +GGTGCTTGGAGTCTGCAGCCCAGTTGGAGAAGCACTGGCTCAGAGGGAAAAGGGAAGTTT +GTTGCTATTTCTGTAGATTCCAGAGGCAAGGCAAGTTTTAGCTCAGAGACCCACTGGTGT +CTGCCTAAATCAGTGGTTCTCACATTTCAGCATGTATAAGGATTTCCCAGCAAGGTTATT +CAGAAATCCATATTCCTAGTCCTCATCCTCCAAAATACTTTTTTTTTTTTTTTAAAGACA +GTGTCTCACTCTGTTGCCCCAGGCTGGAGTGCAGCGGCACAATCATAGCTTCTATCTCTG +CCTCTCAAGTAGCTGGGACTACACGCGTGCACCACCACGCCTGGCTATAAAATATTCTTT +TCCAGTAGCTCTAAGGTGGGCACCAGGAATCTGCATTTTCAACAAGTGCCTTCAGGAAAT +TTTAATGTAGGTGGTCCAAGGCCAGGTGTGGTGGCTCACACCTATAATCCCAGCACTCTG +GGAGGCTAAGGCAAGCAGATCACTTGAGCCCAGGAGTTCAAGACCTGCTTGGGCTGGGAA +TATAGGGAAATCCCATCTCTACAAAAAAATAATTAGCCAAGCATGGCAGCGCATACCTGT +GGTCCCAGCTACATAGGAGGCTGAGGTGGAAGGATTGCTTGAACCCAGGAGGTGGAGGCC +GTAGTGAGCTGTGATCACGCCACTGCACTGCAGCCTGGTGCCAGAGTGAGACCCTGTCTA +AGTGAATGAAGGAATGAATGTAGATAGGAAGGTATTTAGGTAGGTGGCTCATACTAGGAG +AAGCACCTGGGTGGAACCTCTTAGCTTGGCTGGCTTCCTTCACTTAATCCTGCCTGATCC +CACGTTCTTTAACCTGAAATGATCTTTGTATTTTCCTGTCTCTTTTTCCATGTATGGACA +AGCTGTGTTGTTCTTTATTGCCCTGAATAAAGGGTTATGAAAAAAAAAAAAAAATCTCAT +AGAGGGAAATACTTTCACATTGAAGGTGACTTAGGAGAGCTTAGAAAATGAATAAGGACT +CTAATTTTTTACTTCCACATATTGATAACATTTTGAAAATACATGCACAGAATAAATAAA +ACTTTTGATACCAGTTTAGGGGTCCAGGCTGCCTACCTGTTGTGTAGAGTTTTATTGGAA +CGCAGCCACATCAATTTGTTTGCACATTGTGGCCACTTTTATGCTACAGTGGCAAAGATG +AGTCGTCAGGAAAGTGACCCATGACCTACAAAACCTCTAGTATGTTCATCCATCCAACAA +ATATTGAGTACCCCCTGTGTGCCAGGCACTGATCAGTACTAGGAATATGTCAGTGAACAA +AACAAGCACAAATCTCTGCCTTTGTGGAGCTTGCATTCTAGTTGAATCTCAAATTCTGAG +GCTTCTAGGGACCAGGCAGGTCACATAAAAGAGTGAAAAGCACGCTGATGATGAGAGACA +GTAGGGGGTGGTTGAGACTGGCAAACTGGTTAGTGTATATGCCATTTCAAGGGGCAGCTA +CTAATTTGCTCTAGCTGTGTTATCCTATAGAGATATCGCCACATTTTTGACATATTTTAT +GTGAAGAAGGAGAAAATATGGCATGTGAGTTCTCCCAAGTTGTAGAGTTTGTTTTAGTTT +TTGTGTTTGAGACAGGGTCTTGCTCTCTCACCCAGGCTGGAGGGCAGTGGGTGATCATGG +CTCACCGCAGCCTTGAACTCCTGGGCTCAAGCAATCCTCCCACCTCAGCCTCCCAAGTAG +CTGAAACTACAGGCGTGCACTGCCATGCCTGGCTAATTTTTAAATTTTTTGTACATACCC +TGTCTCACAGTGTTGCCCAGGCTGCTCTTGAACTCCTGGGCTCAAGCAGTCTTCCTGCCT +CGGCTTCCCAAAGTGCTAGGATTACAGGTGTGAGCCACTATGCCCAGCCTCTTCCAGTTT +TTACGTGTTGGTAACCAATTCAAAAAATGTTAAAACACTTTGTGGGCTGTTGTGTGTTGT +GGAGTGGCCATGCACAACTGGTCACAGGCTGGATTCAGCCCGTGGGCTGCCTGTTTTCAC +CTCTGGCCTAGCATGGAGTGTGGACCATCGTCTGAGTGGATGGAGATACTTGAGACTCCT +TTAGATTCCAAAGGGTAAAACGATCACTTTTCTGCCTTTCAAAGAAAGTAAAAGTCTACT +GGAAAAACTAAAAACAAAACAAAAAAAATGTGGCTTAAAATCTGTCCCACCAGGTGGCAG +CATACCATCACAAGTTAAAGCCTGTCTGGGCGATGATAGCTCTGGGTCCCTAATTAACAA +ACATTTATTTACTGTTTGCTCCTGAAGAGTGTGATACTAACACCATCTGTCCTTTTCCTC +CCAGGAAAGCTCGTGTACGAGCGCATCTTTTCCATGTGTGTGGATAGCCGCAGCGTCTTA +CCAGGTAATGTCGCAGCTGTTCCTGGGGTGTCATTCTGCCCTGGAGTCAGGACTAGAAGG +CTTTTATTGAGTCAGGATTCATTGAAGCTTGATAAAGGTTTTAATTTTGGGTGTGTTAAA +GTAAAAGAAACACCTTTGAAGATTTCTGATCACCTCAGTCTTCTAAAAACATTAGAAGGT +TTCTAAATGGCCCGTGTAGGAACTCAGGCAAGTCATTTGAATCTGCAAAGGCCTCACAGT +TAGATTCAGCCAAACTTTCACACGAACATATTTTCCTCTGCTGCTTGACTTTAATATTTT +TCCTATGTATCGTTCCCTCCTAAGAAGCAACTTGCTTGGAAAAAAAAATCAAAAACGACT +TTATGCATATTAAAGAATGATGTCAAATAGATCAATAGTAATTGATGCTTTGAATTCACA +ATCTATACCCAAATGATTTTGCATTAAATTGACTGTCAATCAAGTTTAAATTCCCAGGAG +GTTATAATGGGACAAGTGGATGATGAATTTCTTTTGTCGTATAAATGGTAAGAATGATGT +GTCTGGCAATGCAGGACTCTCAGCTGCAGCATCCTTTGCCTTTATTCCTCTTTTTAACTT +CCGAGCACTGCTATGAGGAAACGTTCTCATCCGTCCAAGCTAGAGCAACCAGCTTGCTCC +ATTGCCGCTCCACTTCCCTCCGCTCCTGCAGTGGGGCTTCCCAGGAGGTGAATAGAAAGT +GTTTGTGACAGTAACCTATAACCTGACCTATATTCTTCCTTCTTTCCTCTTTCCTTTATT +CCTCCCTCTCTCTCCTCCTCTCTCTTCCTCTCCCTCCTCCTCTCCCACCCTCTCCTTTTC +TCTCTCCTTCTGCTTCCTATCTGTCCATCAATCGATCAATTTATCTTTATTTAATTTTTT +TGAGATGGACTCTTGCTCTGTCACCCAGGCTGCAGGGCAGTGGCACAATCTTGGCTCGCT +GCAGCCTTCGCCTCCCGGATTCAAGCGATTCTCCTGCTTCACCCTCCTCAGTAGCTGGGA +CTACTGGTGCCTGCCACCACACCTGGCTAATTTTTGTATTTTTAGTAGAGACAGGGTTTG +TACCATGTTGGCCAGGCTGGTCTCAAACTCCTGACCTCAAGTGATTCATCCGCCTCGGCC +TCCCAAAGTGCTGGGATTATAGGCATGAGCAACCGTGCCCGTCCCTTTTTTTTTTTTCTA +TTTAATATTTTTACTTTTTCATCTTTGTAGACACGGGGTCTCCCTATGTTGCCCAAGCTG +CTCTCAAACTTCTGGGCCCAAGCAGTCCTCCCACCTCAGCCTCCCAAAGTGCTGGGATTA +TAGGCATGAGCCACTGTGCTTGGCCTGTCTTTTTAATACTATTTAATGTGCACATTTGTC +AGAAAGAAAGAGACAGAACTCAACAGGCTTTTAGGATTTTTAGCTCTTGAAGGCTTTTTA +GGTCTTGAAGTGCTTTTAGGACCCATCTTGTTTCATCAGAGATGGGCAGACCCAGTACGG +AAGAGTCTTGCCCAGGGCCCTGCCACCAGCTACTGAGAGCCTTGCTCTTTCTTAGTGCTG +CATCTACATTGTCCAGTACAGCAGCCACTGGCCACGTGTTGCTCTTGAGCACTTGAGATG +TGGCCAGTCCAAATTGAGATGTGACGTAACTATTAAAAAAGACACCGGATTTCAAAGAGT +CAGTACAAGTAAAAGACGGTAAAGTAGCTCACTAATAGTGTTTATGTTGATTACATGTTG +AAACGGTATTCTGGATGAATCGGGTAAAGTACATGATTAAAATTAATTTCCCCAGTTTTT +GACCTTTTTAATGTGGCTCATGTGGTTTTTCTTTGGGACCCTCCACGCCACTGCGTCACA +CCTGTGACGATGTTTTTTCAGCAGCTCCTCCTATGTTCTGGCCATCTCAGGGTTGGAGGC +AGTGATCTGGGAGAGGCAGGCAGAGGCCAGCCCAAGTGGAAAGGAAAGGCCTTCTCCGCT +GGCTTGAGGATTTGGGAAATCTGAATTGTTTATTTATTTATTTATTTTTGAGATGGAGTT +TCACTCTTGTTGCCCAGGCTGGAGGGCAATGACGCAATCTCAGCTCACTGCAACCTCCGC +CTCCTGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGTGTG +CACCACCACACCCAGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCACCATGTTGGC +CAGGCTGGTCTTCAACTCCTGACCTCAGGTGATCCACCCACCTTGGCCTCCCAAAGTGCT +GGTATTACAGGCATGAGCCACCACGCCCGGCCGAATCCATTTATTTAATATACACTTGCC +AGCATGTAGCATGCTATACCATTGGCAGCAAACTTGAGCCAACAGGTGGAACTGAACCAA +AATAGGTTTTTTTTTTTTTTTGGCAACAACAGCATTTAAAAAAAAATGACTTTTGATACA +GGCTCTAGTTCTTCCTATTGTTATATACCCAACCTCTTAAAAATTTTCATATTTACCTGC +CTGGCCCCCAGAAGCATTTGAATTTGCCTCTACTGCAATAATCTTCCTTTCTCCCAGTCT +TCAGTGACTATACAAACAACATTTTAGGGCCAATTAAGGAAAAATTACTAATAACTAACT +CCTTGCCTAAACTTAAAAGTTCAAAACAACAGATCAGTCCTCGTTTAGATACATTAATTA +TAGCACTTTTATCACTAAAATTCTTCCCTCTCCAAATAACTATTTTTGATCTTGAGCAAA +GCAAATGATTTGGTTTTTTTTTCTTTAAATGATATCATTGTTTGTTTTCCTTTTAGCTAA +AATCTTCATCTGCTTGTGTTAGCTCCAGTTCCAAGAACCTGAAAAGAACAGTAGATTATG +TTTTTCAAAGTTGTTGGTGATCTGAGGAATGACTCTTAAGTATAATTATCATGAAAGCTT +TAGAAATCTCCTGTGCAGAATTCTGCCCAAAGAGATTATGTGTGAAGAGAAATTTGGTGG +CATTTGTACTCATTCTTTCCATTTAAATCAAGTTCTGTTGGGTGAATTTCATACTTGAGC +CCTTTGCCTTCAGGAATTTTAACTAAGGTATAGCTCTTCGGAGTTGAGAAAGATACAGTG +TCTTTTGGGTTCATGAAAATCACACACTATTAGATGTGGTCATTTTTTCCCAACAGTTCT +TAATCCAGCTTATGCATAAAGAGACCATCGACTCTGAGAAGTCAAATCATTTTATTTCCA +GCTTGGGAGAGATAATTTGGGTTTATTGTATTATGGTTCCCATCACCATCTTCTCAGCAT +TCCCATCTTCAGTTTTCCCCTGTGGCTGATGTGGGCCACATCGGGATAAGCAGTGGCCTT +AACTGACCTGGCCTTTCCAGCACATGCTAACTAAGATGGTGCCAATCCCTATAACACTGT +TACGTAAAGAGACCTCTCGCTGCTAGGGTAGAGACTTGGCAAATAAATGAAAGAACTAGA +CTCATTGGTCTCCTGCCTTCTCTTAAAATACCCACAGAAGTTCAGGTTTGAAAAAAAGCA +GCACCATAAAAGAAAAATAAGTGGGAGCTAGAAAAAAAATCTCTGTTCTTTGTTATATTG +AAGTGTCTTCTGAATTAATTTCCAGATTTTGAAGGAGTCCCCATGTAGCAGCCCAAGTGC +TGAAGTCTAAACTGTGTCATGTCATTGCCATTCCTGTGCCCAGAACCCTTCAGGGGGTTT +CCATTATGTTTAGAAAAACTCTCAAACTCCTCACCAAGGCTTCAGCCCTGTATGAACTGG +CTTGTCATGCTGGCTGCTCCCCTTTCTGCTCAGCAAATTGGCTTGCTTTTTGTTCTTTGA +CCATAGTGAGGTTATACCTACCTCAGGGCCTTGCACTTGCTGTTTTCTTTCCCTGGAATA +TGTTTCTTCCACATCTAGGCATGGCTGGCTCCCTTTCGTAGTTCAGGGCTCAGCTCAAAT +GCTGCCTCTGTGGGAGCCTTCTCTGACCACTACATCTAATGAGCCCCTTCCCCTAAATCA +CACTCAAGTCACTCTTTATTCCAATACCTAGTTTAGTATCTTTAATAGTACTTACTGCTG +TTAGATATTATCTTATTTGTTTGCCTGCTTATTCTCTTTCCTGTTTAGCATTTGTCTCAC +CCCACTGGAATGTAAGTTTCATGAAGATAGGATCTACCTTGTGCACTGTTATCTCCCCAA +AGCCTGGAACACCACCTTTAGTTGGCCCTTAAGGCATTTGTGTTGAGCACATGAAGTAAA +GGAATATAATATTTAGTTTGCTGTAAGATTTTAAAGTCCCACGTAACATAATCCTTTTCC +TAAATTATCTCTTGAGCTGGAAGGAAAGCCTAAAGATTCTGTATTGGTGTATGCAGATTG +TCGTATAGCTTGTAGTCAATGCGTGTATGCAAGGCAGCCTGCCTTTAGCCTGATTTCCAA +CTCTTTCAGGCAACCTGAACCAGTTTGTTTTAGCCATTGCTGAATCTCAGTTCCTTCAGC +TAGACAGTGAGAGATTTTGTAGATGACCTCAGAGACCTATTTTTGCTTTTGGATTTTAAG +CCACAAGATTCAGTCATATGAAGGGAAATTAACACTGCTCTTCCCTCTCCCCAAAGAGAA +GATTGACAAATGAATGTAAGAATAACTGCTATCTTTTCCTGTCTGGATCTCTTGAAAGTA +GAAAAAAAAGTTACTTCATGTGTAGAGATCTAGGCTGGAAAGGGGAAAATGGTCATTTCC +CATCCTTTTGAAAATGGTAAGCAAATAGTTCTCAAGTGAATGAAGCATGCCAGACATCCA +AAAATAGAGTGAGGAGATTGCAATTTCAAAATATCTGCAGTGATTAGTGACTGTTCTCTG +CTAGAGAAGTACCTAGAGGTTTATCTTTTTTTGCTGATTCTATGGGAATTTTGATCACCT +TCATATACTACCAAATGACAGAATCAGGGATGAAAATGACTCATTGCAAAACAGGATGAA +AGCCAACAAGCTAAGAATCATTTGCTATATTCTAAAGTAACTAACTTCTCCCTTTTAATT +TATTTATTCATTTTTTAGAGAATAAATAAATAAGGTCTTGCTCTGTCTTACTCTGTCTCG +CTCTGCCCAGGCTGGAGTGCAGTGGCTCAATCATAGCTCACTGCAGCCTCAAACTCCTGG +GCTCTATTGATCCTGCCACCTCAGCCTTCCAAGTAGCTGGGGCTACAGGCATGAGCCACT +GTGCCTGGCCAGCTTCTCCCTTTTTGAATTAATCCTAAAAGTATAAAACATCCAGTGGTG +GGATGGAGCTCTAATCTTTGCTGAAATCATTTCCATGTGAGAGGTTAACAAAGGCCTTCA +TGGTGTTTGTAAGTTTTGTGTTTTTTCTTTCATTTCTCCATATTCTCTTCCATTCCTTAA +GATGTATGTCAAGTCCAGAACTGTGAGAAATAAATTTCTGCTGTTTAAAAATATGTATGT +CAAAATCAAGCTTGGGTACCAGTTCCAGAAAACTCAAAATAACAGTAATGAAGGTCAGGG +CCGATGGGCCAGCTAGCCCCTGGTACCAAGGATCCTCACTTCTGTCTTGTTGCTCTCATG +GTCAGTATGGCTGCAGAGGTTCCAGCTGTCATGTCTGCATTCCAGTCAGTGAGCAGAAAG +AAGAAGTGAGGGAAGGCAAGCCCCTTTCCTTAAAGATACTTCTCAGAAGTTGCCCTTCTA +TTTATATATCCTGGGACCAGAACTTGACCCACGTGACCACACCTAGCTGCAAGGATGGCC +CTGTGTCCTGCAGGAAAATGCGAGTTCTTTTATTAAAGAGGAAGAGAATAGCTAATGGAG +TAAACTGGCAGTTTCACAAGATGACTCTCTTGGAGCCAGTCGTGAGCCGGCAACATAATT +CTGGCTGGTTTCTCACCTCAGAGGCCTTGTTTTACCTTCCTCTGGCCCATTGTGATGTGT +AGAGCAAAAGCTTAGATCACATTTCATGTTGCAGTCGCAGGTCCGTAAAGCATCTGGAAT +TCTCAACAATGTTGTCATAGTGACTGGTAGGTAACCAAGAACCTCTGGATTATATTAGAG +GCAGTGGCTAAGAATGTCGGCCGCAGGGCCAGAGTGCCTGGGTTGAATTCTAACTCTTAC +ATTTGCTTGCTGTGTGCCTTGGGTGAGTCACTACATTCCTCTGTGCCTTGGTCTCTGCAT +CTGTAAAATAAGATAATAAAACTACGTACCTCAGAGGGTTGCTATATGGGATCAGGTGAG +CTGTCTGTAAAGCACTGCGAACGACACTTGGCACTTAGAAAGCCTGTGTCTGTGTAAACT +ATTGTTATCATCAGTTACTTCCTAATAGTGATATTTGGAAGGAAAGAAACAGGCTGAGTC +ACCCCCTTTTCTGCTCCAGGGTAATGTATTCCCATCCAGGGACTCACACAGATCCTGAGA +TTTAGGAGGGCTGATGGATCTTGTTTTTTGTATTACAGATCACTTTTCTCCAGAGAATGC +AAATGACACGGCCAAGGAAACATGCCTAAATTGGTTTTTCAAGATTGCCTCCATCAGGGA +ACTCATTCCAAGATTGTATCCTTTTTTTTTTTTTTGGTCTGATGATTTTAAAGATAGGCT +AAAAGAATTGTACTGTTAATAGAAGCCATGTGATGGGATGCCCTGACATTCTTATTGAAA +GTTTGGTCCCGTTACGGTTGCTAGCCTGAAAACACATACAGGGCAAGCCACATTGTAGAA +ACCCTTGGACTCTTGCTCTTTCCAGTTTTTTGTCTTTTACTTTGAATACGATGCCATGTG +TCAAGCATTTGTTTCCTTGAGGAACATTCCCACCTTAATTCTCTCAATTAAAATGCTTCA +TATTTGTGTTTTCTCTGATTCCAAGAACTTGAAAGAACAGGGTCAAGCTTTGCAGGGCAA +ATGCTACTATTGAAGAACAGATAATTTGACTTATACATAAATTCCATCTTAGTTACCTAA +AGTTCTTTCTTTCCCCATAAAGCATTGATTAGAAATGCTCAAAACCCAGTTTATATTTCA +GCATGCAACTATGAATCAACGTATAACATTTCCCACAATTTATTTCAAATAAGTATGAAA +CTTTGAAAACCATATGTAGAAACCATAAGCTACCTTAGTTCGCTGGATTGTTGAGGGCCA +CTGTGGTCCCCATCTCCTAAGACCCGCCTACTTCTATTCATGGATAGTTTAGTCTTTTCT +CCATAGGGAGTAGACCTTCTGGAAAACATCTTCCTTAACAGGATGTTTTTGTAGTTACGT +GGAGGCATCCATCCTGAAATGTAACAAATTCCTCTCCAAAACGTAAGGCTCTTCGGTAAA +ATCTAGAACCATAAAATTTCTAAAAATCTCCCATGTGTACACAGATAGTAATGGCAATGT +AATAGTAGCCATTATTCACTGAGTACTTAATGTGTGTTAAGCACCTTCTGTTCTTTTTCT +CATTGAATCCAAATGAAAACTGAATGAAGTAGAGACACCATCCTAATCCCCATATTAGAG +AGAGGAAAACTCAAGCCTGGAGAAGTTGGTTAAGGAGGTCATGGAAGATCAGCTCAACTG +GATTTGAATCTTGGCTGTACTGGTACTAGCTGTATGGTCTTGAACAAGTTACTTACAGCC +TCAGAACCTCTGGCTCCCTCTCCTGGGAACATGACCCTAAGAAGAGGTCTGAGGGGGTCC +TTTGGGTCACACATGCAACAATGAGAGTCACCCCTGGCACACGGTGGGCCCATCCTCCAT +GTTGGCTGCTGTTGATGATGATGATGATGAAAATGACGTCAGAAGCAGAAGCCTTTGCCC +TTAGTGGCTTAGGTCCATGCCACTCAATTTATCACAATGTTTTGAGAGTAGTTACAGGAC +GTGGGGGACCCAGATCTGCTTTCTGCAGAGCAGGTGAAATGCTGAGTCATGTTAGATAGC +TAGATAATAAATTCCTTGAAGCCCGGGAGTGACTGATTCATGGTGCTCCACAGATAGCTC +TACCGATTGGATTTAGAATTTATCTCAAGTGTGTTGGATTTGGATCTAGGGTTGCCTGGA +ATAGTTTGGGGGAATAACATGGGGGCTGAAGAAACATTATTTTGCCTCACCAGTTGGAGG +AGGATAATGCCTTAGGCAGAGGGAAGACATACGTTGCAGGAGAAATAAATTGTAATTCAC +ATTGTTGGTGGTTGGAGGATGTCAGATGCCAGCCTGAGATTCACGGAAGGAACAGGGTAC +GGGACAGTAAATCTGTGGCAAACGAAAATACATGTGGAGAGAAGATCAAGGGGTGCCCAG +TCGATGGAAAATAATTGAAGACAAAAACTGTTAAAATTAATAAAATAAATGTGACCTCGA +CTGGGGAAAAAATGTGGTTAGCCTCCACCACTGAGCAAATGATAACGATGAAAGAAATCA +TTCAATGAATGAATTGTATCAGAAGAGAAAGACTGTTGTTACATTGCCTTAGAAAACTGA +AACTTTGACCTTGGTTTGTTACTGAAACTTGATTTTTCCCCCCCTCCCTGAAATTTAGGA +AGTCTTTATCTTTATTTAAAAAATTAAAGAACAGCGAGTTCTCACGTCGAATATAATGCT +GGCCTGTTTTTGTCTCTTGCAGGGGAATTTCAGAGTGCCTGCCCCGGTTGACATGCATGA +TCAGAGGGATCGGAGACCCACTAGTGTCGGTGTATGCCCGTGCCTACCTGTGCCGGGTAG +GCCATGCGAGTCACTGCCCTTGACGGCACGGCTGCCACCCGTCTCCTTGAATGTTCACAC +AGGGCCCTCCTTCCCCACCACCCCGCAAGTCATTGAGAGAAGGACTTTATTAGTGGCTAA +TTTTAGATCATGGCTCTGCCACAGAAAGTAGAACTGTAGGGTTTCTTTTAAAAATTAATT +TTAAAGTAGACCAACTTACTGTAGCTCTAATTAGGGGACGTTTAAGGTCATCTTCTTACA +AATGAACTGGTTTTCAGAAGTAATTGTTTCTCAGTTCTTGCTGGGAAGGAGGTTCCCAGG +GCCTTTGGGCTAACAGGTTGCTTTTCATTGACTTCAAACATGCTCTTCCTTTGTCTTGAC +TTTGATTGCTTTATTAGTTTTCTGCTTGGCAGGGGAGCAGTGTCCCACATGATGGCAGGC +CTCAGGGTCTGTGTGGCCTGGCTTAGGTGGCTGCTGTGAAAGGGGGTAGAGGGACTGATT +AGAAATTACTTGCCCATGCCCTGCTTTAAAGCACCGTGAGGCTTCAGCTAAGCTATTAAG +TTTTTTGTGTATGGAAAAAATGTAACCAATGGAGGTTATATGGTCTTTCTTTTTTTTGGA +GATGGAGTCTTACTGTGTCGCCCAGGCTGGAGTGCAGTGGCGCCATCTCGGCTCATTTCA +ACCTCCACCGCCTGGGTTCAAATGATTCTCCTGTCTCAGCCTCCTGGGTAGCTGAGATTA +CAGGTGTCCGCCACCATGCCCGTCTAAGTTTTGTATATTTAGTAGAGATGGGGTTTCACC +ATGTTGGCCAGGCTGGTCTCGAACTCCTGACCTCAAGTGATCTGCCCACGTTGGCCTCCC +AAAGTGCTGGGATTACAGGCGTGAGCCACTGCGCCCGGCCAGTATATGGTCTCTCCATAG +TTTTCTTCAGCTCACACAGGGGCTTTGCCTCTGTCAGGACTCCCCCTAGCAACGAGAATC +TTCCCTATCGTCCCATCAGTATTGCACATCCTTAGAGAGGGATCATTGCACCTGATAAGC +CCCAGACTTCCTTGAGGACAAAGCTGCAGTTAGAGCCTCCCCCATGAGTTTGCACCTTAT +TAAATCAGAAGGCGAGAACATGTAGCCTGTGATTTGCCTCTTCTGCATGACAGCCAGCAA +ATGTCGGAAGCCCTGTGGTCTCTCAAGTTTCACGAAAAACTAAGTCAGTGCCCTCAGAGT +GAGGAGCAGATATCCATTAGGAAGGGCACTTTTTATAGGTCTGTTTCTTGATACTGAGAA +TGAAAGAAAAAGCCTTTCGTTTAAGGGCATCCTCTTCCCTCTTTGCAGCAGAGGCCAAAG +TGTGTATGCATCGCCCACTGCTTGAAACCTGGGGGGGATTTTCCATCCAGAGATATCAGG +TGTGTTTCCAAGGACAACTTTTGAATATATTAAAGCTTGAATACTCCTCCCAAGTCAGTG +TTTGCTGAGGCCCTACTGTGCACAGAACACAATGCCACATCCTCTGGGAGAGATGCAAAG +ATATTGTTTGCATATTTCTTTTTCCTTTTTTTTTTTTTGAGATGGAGTCTCACTCTGTCG +CCCGGCTGGAGTGCAGTGGTGTGATCTCAGCTCGCTCTAACCTCTGCCTCCAGGGTTCAA +GCAATTCTTCTGCTGCAGCCTCCCGAGTAGCTGGGACTCCAGGTGTGCGCTACCACGCCC +AGCTAATTTTCGTATTTTTAGTAGAGACGGGGTTTCACCATGTTGGCCATGATGGTCTCA +ATCTCTTGACCTCATGATCCGCCTGCCCCGGCCTCTCAAAGTGCTGGGTTTGCAGGCATG +AGCCACTGCACCCGGCCTTTTTTTGTTTTGTTTTGTTTTGTTTTGTTTTTTTGCACCAGA +GTCTCACTCTGTTGCCCAGGCTGGAGTGCAGTGGTGCAATCTCAGCTCACTGCAACCTCT +GCCTCCTGGGTTCAAGCGATTCTCATGTCTCAGCCTCCGGAGTAGCTGGGATTACAGGCA +CCTGCCACCATGCCCAGCTACTTTTTGTATTTTTAGTAGTGACAGGGTGTCACCATGTTG +GCTAGGCTGGTCTTGAACTCCTCACTTCAGGTAATCTGCCTTCCCCGGCCTCACAAATTG +CTGGGATTACAGGTGTGAGCCCCCGTGCCCAGCCTTGTTTATGTATTTCTTCTCTGCTGC +CTTTTACCTTGTAGAACATAGCAAATGCTTTGAACACACCTTGACATCATTTGAATAAGG +CCTGATATCGGAGACCCGGTGATAAAGACTTAGAATCATGCTGTCTCTTCTGCAAATAAT +TCTGGTTATTAAAGAGAAATCAGAATGTGGGGAAGTATGTATTTTTTGCAAGCCTGTTCC +CTTTTAATGTTTGAGATCAGGTATGTGAGTTAGGGTACACGATCATGTTTGTTACATATA +AAGTGCCTTTGAATGGCAGATGCAACTTGAAACACAGTGACAATGAGGAGAAGATGCAGA +GGACAGAGCAGACCCCCCACAAGATTGGTAGTAGAGTGCCCTGCGTCTGTTGAAATCATT +TTTGTCAGTCCAGGCAATGCATTGATTCCGCTGGTTGGGTAGTTTCTAAAAGTCTCTTTA +ACATTAAAAGAGTAAGAGAGACCAAGCGCGGTGGCTCATGCCTGTAATCCCAGCATTTTG +GGAGGCCGAGGCGGGCAGATCACTTGAGGTCAGGAGTTCAAGACCAACCTGGCCAACATG +GCAAAAACCTGTCTCTACTAAAAAATACAAAAAATTAGCCGGGCGTGGTGGTACACGCCT +GTAGTCCCAGCTACTCGGAAGGCTGAGGCACGAGAATCACTTGAACCCAGGAGGCAGAGG +TTGCAGTGAGCCAAGATCGCGCCACTGCACTCCAGCCTGGGTGACAGAGCAAGACTGCCT +CAAACAAACAAACAAAAAGAGACAGCCTGTGTATTAGTAAGATTTCTTTCAGTTCCAAGT +GGCAAAACCCAGTTCATACTACTTTAAGCAAAAGTAAGAACTTACTGGCCAGTGTCTGGA +GAGGCCAGGGTTAGTGCAGGCATGGCTGGATGCAGGCCCTCAAAGGGTGCTGTCAAGAAT +CAGCCTCTCCCCACATCACTCAGCTCTGCTGTTCTTTGAGTTGGCTTCATTCTGTGGCTT +GCTTTTTTTATATGATGGCCCATAGCGGCCTCTGGCTTCCATCCTACCACCTTAGGAACC +TTATTGGAAAGTGTGTCTTCTTGCCAGTAGATCTAGCCAGAGCCTCAGGGCTGATTCTTG +GTGGATTACCTCGGGTTGTTTGTCCACCCCTAGACTAGTCACGTGGCCATGGGTTGGGGT +CTGGGGTTGGTGTCTGGGTACTTACTGACTGGGTCACATGCCCTTGCATGGAGCTCAGGG +TGAGGTGGATCTAGCTCCACCACAAACCTCATGGTCCAAGAGGAAGGTTTGATTCCCCAG +AGACAAATCTAATTTGCCGATACCAGCAATGGGGGGGATGAATGCTGGGCAGGCCGAAAC +AGCAGATGGGAATCATGAGCAATACCCTTGCTGCTCTGGGTAGAAATCTTTTAGACCCAA +GCAGATATCCAAGCTGCTCATTTGGCCCGATGAGAAGAGAAAAACAGAAAACAAAAGCTC +TGAGTGGGTAGAGCGTGGGGGGAGCTTGAAGCTGTTATTAAAGGAAGGTATGATTAACTC +CTAACTCACAGCCGCTTCAGCTCATCTCCATGGCTCAGCCACCAGGCCAGCCTTTGCTGT +CACCTAACAGATAATTATTGTCTTTTCTACAATATGATTAAGTGGAAGGAGAATCAGAAC +ACTGTAGAACTGGATCTGATATTTCTTGTTAGCATATATATATATATTTAATCTATGTGC +TTGTCCTTGAAAACAGCACTTCCTGTACCCAGCAATCACAGAGCTGCTCTTGGAATTTAA +CACCCTGGTGGTTCTCAAATGCCATCTGAAAAACATTATTAGTGTTACCCATCATGACCT +CTGGGTAGTGGAAGGTGAATGGGAGAAATCTCTCCCCATTTGAAGAAATAGGGAACCAGT +CTCACTTTGTTGCCCAGGCTGGAGTGCAGTGGCACAATCTTGCTCACTGCAACCACCACC +TCCCGGGTTCAAGCGATCCTCCCACCTCAACCTCCCAGGTAGCTGGGTCTACAGGCGTGC +GCCACCACACCCGGCTAATTTTTGTGTTTTTAGTACAGAAAGAGTTTCACCATGTTGACC +AGGCTGGTCTCAAACTCCTAACCTCAAGTGATTGGCCCACCTGGGCCTCCCAAAGTGCTG +GGATTACAGGTGTGAGCCACTGCAGCCCAGCCTACGAAGTTGTTTTTGCGGTTAAGCAGC +AATTTGGAAACGAAGCATTTCTGAGGAGCTCAGTTTAAGAAACACTGTGATGTTGTGTTT +TAAACCTATGAACTCCCCTCCGTAGCTCATCCCTCTACTTTTCCATCTAACCCCAGTACT +GGCACCTTCTCTATGATTAGTAAATTTCTTCAGCTAGAAATGTTACAGTCTGTTTTTTAA +CAATGAAGTCAGGACCCAGTGGATTATAGCATTGTTACACTTCATGCTCATGTTATATAA +AATTGCATAAAATGTATTAAAATTTATGTCTGCTCTTATCTCTGCCTTGCAAAGAATGAA +TTTGTATAGCTTTTAACTAAGCATGTAACGGGGGCAGCACCACATCTGGAATTCAAGCTG +ACTTTCTCACGTACCGTAATCTTTGTGCTTGGTCTAATAAGTACAACCCCATGTGTGTTT +ATCATTTTTTTATTGTATGCACAATCTTGAGAGTACATTCCTTTTTAGTTCTGTATTGAT +TTGTTCTCTTGGTCGTCTGTTCAGAAATACATTCAATACCTTTGGGGAAGGGCAAAGATG +ATTTCTGCAAATGTTGCCCTTTTTTATTAAAAATAGCTTCTGTGGTCTTTCTTATAAAAG +CAATACATGTTTATTGAAAAAGAAATCAGGCTGGGCGTGGTGGCTCACACCTGTAATCCC +AGCACTTTGGTAGGCCGAGGCAGGCAGATCATCTGAGGTCAGGAGTTGGAGACCAGCCCG +GCCAACATGGTGAAACCCCGTCTCTACTAAAAATACAAAAATTAGCCAAGTGTCGTGACA +CATGCCTGTAATCCCTGCTACTTGGGAGGCTGAGGCAGGAGAATTGCTTGAACCTGAGAG +GTGGAGGTTGCAGTGAGCCAAGATCGTGCCACTGCACTCCACCCTGGGCAACAGAGCGAG +ACTCTGTCTCAAAACAAAACAAAAAACAGATAAGGAAAAAAAAAATAGGCCGGGCGCTGT +GGCTCACACCTGTAATCCCAGCACTTTGAGAGGCCAGGGTGGGCAGATCATGAGGTCAGA +AGATCAAGACCATCCTGGCCAATGTGGTGAAACCCTGTCTCTACTAAAAATACAAAAATC +AGCCAGGCCTGGTGACACATGCCTGTAATTCCAGCTACTCGGGAGGCTGAGGCAGGAGAA +TCCCTTGAACCAGGGAGTCGGTGGTTGCAGTCAGCTGAAATCGCACCCACCGCACTCCAG +CCTGGCAACAGAGCGAGACTCCATCTCAAAATAATAATAATAATAATAATAATAATAATT +TTCTGGACTTTTTCTGTGTCTATAAACATAGGTATATATATTTTTTAATTTCCAAAAATA +AAATCATACTATAGTCATTATTTGCAACCAGTTTTTCCATTTGTCTGGCTGCAGGTGGGA +ATGGAAGTGGCCCCACATCTCAAAGAAACCCTAAATAAGAACTTTTTTGACTTCCTCCTT +ACGTTCAAACAGGTAAGAGAACACTATCAGAATAGCTCATCGATATAACAGTTCTATGAT +AGCAAATTCACAAAACCCAGTTGGTTTTCCAAGTGGAGAATGCCTTAAAGCTCTTTAAAT +GTGCAAGCCCTGGAAAATTACACTAGCTTCTGTTGTAGACAATTAAAATGTGTTGATTGT +ACTGAATAAGCGGAGAAAGTTAATATGCATGTGTTAACAGGAAACGTCTCCAGTCGATCA +GCCTTGCTTCTGAGCATCTGCTGGCTCCATTTTTATCAGGTTCCTGCTTTCCACAGCGCT +CATTCCCAAAACAGCTCGGCTTGGTGACATGAGAAACTTTCTGTGTTTTTTTTTGGTTTA +AAAAAAAAAAACAACCGAGAAACCAGGCTATTTCTCTCAGGGCTGTCCACATGCTTACAA +GTATGCACAGTCTGTGAGTTGTGTATGTTTTGTTTGTTGTTTGGTTTTTCCCCTCCTTTT +CTAAGTGTTTGTTTGGCCTCCTGTAGATTCATGGGGATACGGTCCAGAACCAGCTGGTGG +TCCAAGGAGTGGAGCTCCCATCTTACCTCCCCTTGTACCCGCCTGCCATGGACTGGATCT +TCCAGTGCATCTCCTACCATGCCCCCGAGGTAACTGCCAGGTGGCTTCAGTGTGACGCTC +ACCTCCTGTATGGTGACAGCCCCTGCCCACTGTGCCCTTTAACGTTAATGGGACCCTTTC +ATAACAGCTATAGCAATGTTAGTGCTAGCCAGCCTTTATAGAGGGCTTGCCATGGTGGCT +GGCTCTGTGCTGAGTGCTTTTCTGAGATAGTCTCATTTTGACAGCTGTGGAAGGGGAATG +TGGTAGCTCCAGAGGCCATGTACCTAAGTGAGGCCACACAGCTAGAAAGCAGTTTGGTGG +CTGGGTGTGCTCATATCTGTAATCCCAGCACTTTGCAAGGCCAAGGTGGGAGGATCACTT +GATTTTAGGAGTTTGAGACGAGCTTTGGCAACATAGCAAAACTCCATCTCTACAAAAAAA +TAGAAAAAATTAGCCAGACACGGTGATATATGCCTATAGTCCCAGCTACTCAGGAGGCTG +AGGTGGGAGGACCACTTGAGCCCCAGAGTTCAAGGCTACAATGAGCTGTGACTGTACTAC +TGCACTCCAGCCTGAGTGACAGAGCAAGACACTGTCTCATTAAAAAAGAAACAAAAAGGA +AGATGGTTGGTGACTTGATACAAACCCATAGAATTGGGCTCCAGGGCCAACAAGCCTTAT +TGCGTCTTCACTTAACCTTCATGTACCCCTTTTGTGTTTATAATAATCCAATAAAGTCTG +TAGAGCAGGTATTTTATGGAAGGAAAACAAAACTCAGATGCTTAATTTCTTTTATAATTT +TATTTTTCTTTTCTTTTTTCTTTTTTGCCAGTTGAAGTATTGTCAGGAATTGAAGTGACA +TCAGAATCATAGCAGACACATATTTTCTTTCTTTTCCAAGACTGAGAAGCAGTTTTAGTA +GAACACCAATTCAAACTGTCATGAAGACTGTGATAGGCCGGGCACGGTGGCTCATGCCTG +TAATCCCAGCACTTTGGGAGGCTGACGTGGGTAGTTCACTTCAGGCCAGCAGTTCAAGAC +CAGCCTGGCTAACATGGATATATAGGTGTATATCACCATGCCTGGCTAATTTTTTGTATT +TTTTTGTAGAGATGGAGTTTCACTATGTTGCCCAGGCCTGTCTTTTGTAAAGACCCTGTC +TCTACAAAAAATACAAAAATTAACTGTGCGTGGTGGTTTGTGCCTGTAGTCCCAGCTACT +CAGGAGGCTGAGGCAGAGAATCGCTTGAACCTGGGAGGCAGAGGTCGCAGTGAGCCGAGA +TTGCACCACTGTACTCCAGCCTGGGCAACAGAGCCAGACTGTCTCAAAAAAAAAAAAAAA +AAAAAAAAGACTGTGATAGATGAAGCTTTCCTTGTCTTTATTTGATCATTGAAAAGTAAA +GAGAGACTACAAAACAAGGACATATAGAGCAAAGCAAAGTTGAAAGACATCTGCCTTTTC +CTAGATCTTGCCAACACATGTTGAAAGCTGTACAGAAAAGAAAAAAAAAGGACATGACTT +TAACCGAGCAATCCCACTTTTACGAATTTATCCTGTAAGTTAGACGAGTGCATAAACATT +ATAAACACACACAGAGATGCACACACGGTTTGTTCACGGTAGTGCAAAATTGGAGGCAAG +CATCAGAGAGGACTGGTTATGGTATGTGCATTCAGTGGGGTGTTAATGGGGCCATTTAAA +ATGATGGAGACTCCCGATGATCTGTACATACTGACGTAAGGGTATTCATGGTATATGGCT +AAGTGCAAAAAGAAAGTTACACACATTGCTGTGTGTGCTGTAAGTGGCAGTGTGGCCTAG +TGTTCAGGTGTGGGCTCTGGAGTCGGGGTGCCTGGGTCTGCATCTCAGCTCCGTTAACAG +CTGTTGTGATAGAGTAGGGAGCAGGTAACTTGTTCCTAACCACTCTGAGTCTTCTCTCTT +TATCTGTAAAATGGGAGCAATATTAATGATTCCTATTTTCTAGTCCGTTGCAAGAATCAA +AGAAGTCACTGTATCTACGGTGCTTAGTGTAGCGCCCCACATCTTAGTACTCGCAGACAT +GATTTTTATATCTGTGCGAGAGAGTTGGGAAGGAGAAATGACAGAACATCACTGGAGTGT +GAGATTTGGGGCCAGCGTAACTTATTTTTCTTTGCCTATCTGTTTTTTTTTTTTTTTCTT +TCTTCCTTTGAGACAGAGTCTCACTCTGTCTCCCAGGCTGGAGTGCACTGGTGCAATCTC +GGCTCGCTACAACCTCCACCTCCCAGGTTCAAGCGATTCTCATGCCTCAACCTCATGAGT +AGCTGGGACTACAGGCATGCATCACCACACTCAGATAATTTTTGTATTTTTAGTAGAGAT +GCAGTTTCACCTTGTTGATCTCGTGCTGATCTCTAACTCCTGGCCTCAAGTGATCCTCCC +GCCTCGGCTTCCCAGAGTGCTGGGATCACAGACAAGAGCCACCGTGCCCAGCCGCCCATC +TCTGTTTTCTAACTTTTCAACAAGTATGCACTGCTTACCTTTTTACTTTTTGAGATTCTA +AATTATGAGGAGAAAAACTGGGACATCTTGTACTTCAGGTGAATAGTCTTACCATTAAGT +AAATTGATTTTAAATCAAGCCAGTATAAAGGAAAGATTGTTTGAAGTTTTGCTGCTGGTT +CTCTATGGTCCTCAGCATAGTTTCAGCAACCACATGCTGTCCTCCGCTTCTGGGAAGGGT +ACCATGAACTCGACTGTTTTCTTGGTATTCCACTGAACGACGGAAACATACAAGCAGGAT +TGACGTGGTGAAATGAGAACGCTTTTTTTTTCTTATTTTAGCGAAAGGCAAAATCAGATT +AAAAACAAAATGTCACAAGGCAGTCTTCTTTTTATTTTAAGCCCCAGTCATCTCAAAGGA +TGGCAGAAGCTGGGAATAAGCTCTAGGAAATCATTATTGCACTAGAATAAGTGATTAAAA +AATTAGGTCAGCTGAATAATAATAAACTCTGATTCTTGGGCACACTTAAAGGACATGCAG +TGTCTTGTTAAAAAAAATAGTCATTTTCAAACTGCAGAAGAATTGATGTCGGTATGGAAG +GTGGTGTTAAAGGTGCATGTGACAATTTGGTGCCTAAAAGCTCTTTGATAATGGCCGCTA +TGAGTCACCTGCAGAGTAGAACTGTGTGTATCCATTAGAGGCCAAGACTTCAAAATAGGG +GATGGTAAAGTTCGGCTGCAGCAATTGGTAATATACAGGGCAGGCAAGTGAGAGAGGGAA +AGGAGAAATACCTTTAGTTGTGAATATCTCATCTACAGAATTTCAAATCGAAATTGAAAT +CCAAGGTAAAAAATCAAGGCATGTCTTAGTCCGTTCGGGCTGCCATAATAAAGCGCCATA +GAATGTTTAAAATAGAAATGCAGCCTTGGCCTGACTTCTTTTCTCTCCTCCTGTACTTTT +GAAGTGGGTAAATAATTATAAATAACCTAATCTGGAGATCACCTTAAAAAATCCAACAGT +TAAATATGGTTGTGGTTCTCCAACTCCATATATATTGGTAAAATGGTCATTGAATTAGAC +ACAAAGACATGCTCTTTTTCCCCCAAAAAGTATGCATGTAAAACTTGGTGAAATTGTCTA +GTTAGTTGTGTTATACTAGTGTCAGTTTCCTAGCTTTAATAATGCATTATAGTTATGTAA +ATGGGAGAAGCTGGGTGGTGGGTACCCAGGACTTCTCTCTACTGTTTTTTTCAATTACTG +ACGAGTCTATAATTAATTCAGAATGAAAAGTCTTTTAAAAATCCTTCAATTGGGATGAAT +ACTCCATTCTCCATGATGTGATTATTATGTATTGCATGCCTATACCAAAACATCTCATGT +ACCCCATAAATATATACACTTACTATGTACCCTCAAAAAATAAAAATTAGGCCAGGCGTG +GTGGCACATGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGCGGGCGGATCTCTTGAGGT +CAGGAGTTTGAGACCAGCCTGGCCAACATGGCGAAACCCCATCTCTACTAAAAATACAAA +AATTAGCCGAGTGTGGTGGCATGCGCCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGG +GGGATTACTTGAACCCAGGAGGTGGAGGTTGCAGTGAGCCAAGATCACACCAGTGCACTC +CAGCCTGGGCGACAGAGCAAGACTCTGTCTCAAAAAAGAATAAATTAAAAAAAATAAATA +ATTAAAAATTAAACAGAAAACAAAAACAGACATCTGTCAGTTAGGGGCAGTTTGAAAAAT +GCTGTTATATCCATGGCATGGATTAAATAGCCATGGATTAAAAGAGTGAGGTAGATTTGT +GTAATAACATGGAGAAGAGAGGGCCATCTAGATTCTCCATTAAAAAAGGCCATATTTAAA +TATCTCCAACCCAGTATTTATAAGAGTATCCCATTGTGTAAAAACAAAACTAGGCTTCTG +TAATAATATATATCCATAAAGCACAGGCAGAATTCTAGATAAGAACATCAAAGTCCTAGA +CAAACACCAAAGTGTTGACAGTGGTGATTTCTAGGACATGGAAGTTGGGAGGGGGGGACA +TTCGCATCTTTCTTGATGCATGTCGATGTTGTTGGGACTTTTGTCTATAAAGCATTTCTT +ATTTTTACAATTTTTAGAAAAACAAATGTTACATAAATAAGTGGCATGTAGGGCCAACAG +CAACAATAACAAAAGCCTAAAAAACAAACCAGCACACCAAGCAAATGCCTGCCTTGTGAA +TCTTCTGAATCTTCAAGTTCTGCTGTGTGTGAAAATGAAAGAAATATGCTGAGCTGCTTT +TTCAGTGGTTGATCCCAGCCAAAGGGCTTGTTTCAATCTCTGTCTGCTTTGAGCTGTTGT +TCATCGTGTTCTTGCCAAAGATAATCAATTCTGTCACTTCTTAGAGGGGAAAAAATCAGT +AACCTCCAGCAGACCTGCCCGAGGATCTATAACATTTGGCTCTCCGAACACTTACATGTA +TTCCCAAGTTCCTTTATGACAACAGAGCCTTTGGTTTTTTAAAGTTATATTCTTGGATGC +ATTTTTAGTGCATTCATCTTTTGTGAGAGAGGGAACTTTTTAAGCATTTAACTTGTCTTA +GTGGTAAGAATCTTTTGTCCATATGTTGGGATTTGCCCTAGTTAATCTTTCCAGAATTGG +TGGGCCAGGAGGTCTCATTTATGTGTGTGTGTATGTGTGCATGTGTGTGTGCACGTGCAT +GCATATGAGATACAGTAAACCTCACGAAGGCATGGGTTTCTGTGTTTTCCTCCCATCTTA +CCCTCAGTGTCTGGAACAGTGGCTGGTATAGTCATCCCTTGGTATACTTAGGGGATTGAT +TCCAGGATCTCCATGTATATCTTTTTTTTTTTTTTTTTTTTTTAAGACGGAGTCCTGCTC +TGTCACCCAGGCTGGAGTGCAATGGCCCGATCTCCACTCATGGCAACTTCTGCCTCCCGG +GTTCAAGCAGTTCTCCTGCCTCAGCCTCCCAAGTAACTGGGACTACAGCCACGCCACCAC +GCCCGGCTAATTTTTGTATTTTTAGTAGAGACAGGGTCTCATCATCTTGGCCAGGCTGGT +CTCGAAATCCTTACCTCAGGTGATCCACCCACCTGAGCCTCCAAAGTGCTGGGATTACAG +GCGTGAGCCACTGTGCCCGGCCCCCACGTATATCAAAATCCATGCTGTGAGACTCAAGTC +TCACAGTCTCACAGTTGGCCCTGTGGAACCCGTGTATACTTGAGTTTGGTGTCTCACAAA +TACTGTATTTTCGTTCAGCATATGGTTGAAAAAAATCCGTGTCTAAGTGGATCCACGCAG +CTCAAAACCATGTTGTTATTCAAGGGTCAACTGTATACTAAAGTTGCTCGTTAGGTAGGC +GTTGAATGATTATTTCTGTGTGTCAGGGAGTGTCAGTGTGATGATTACACAGAATCTCTT +TTCCTCTCTTAGCCTTTTCCAAAGGCCACTTTGCTATTGGTCTTTAAGAATGACTTTTCA +AATGTAAATACCCAAGAGTGGGTTAGGGAAGCCATTTATGATGTGGTCAATTTTGTCACC +AGCTAGGGTGCTTTTGGCTGCAAGGAACAAACATCTAACTAGTCTGGCCTCCACATATAA +TTCCATGTGTCCTCCTCCACAACAAGTGGAGGCTCTCGGGTGATCAGCTTCAGTGCATCT +TTTTGCTCTGCTGTCCCTGATTAGTAGCAAGGTGGGGGCAACCATTCCAGGCATCACGTC +CAGAGCCGACAGCATCCAGGGAATCTTTGATTCTTGGGTCCTTGTTTAAGAACAGGAAAC +CTTTCTCCAAATCCCCCCGAAGACTTCCCATCCTGTCTCAGCAGCTAGAAATGGATCATG +GGCAAGGGGAACGAGAGCCACTGTGATTGGTTTGGGTCTGTATTAATCTGCTTGGGCTCC +CTTAACAAAATACCCAGACTAGGAGCTTAAACAACAGACTTTATTTTCTCATAGTTCTGA +AGGCTAGGAGACCAAGATCAAGGGGCCAGCAAGGTTGGTTTCTGGTGAGGCCTCTCTCCT +TGGCTTGGAAACTGCCACCTTCTTGCCGTGTTCTCACATGGCTTTTCCTCTGTGTACACG +CATCCTTGCTGTCTCTTCCTATAAGGAGGTTAGTCCTGTGGGATTCGGATCCCACCCTTA +TGACTCCATTTAACCTAGAATAGTGATATTAGGGGTTAGGGCTCCAACATAGCAATTTAG +GGGAGATATAATTCAGTCCGTGACAGAAGCCAACCTAGTTTATGTGAGGCATAGATGGAA +ATCTGAATAAAATCAGGGTTTTGGGGTAGGGATTCCAACAGTATCTCCAACGTCAGCTCT +CACTTATTCAGGCAACATGACAGAGAGGGGTGCCACCAGAAAGGGTGGAATTGCACTTAA +GAACCCTCCTTTTATTTTTTTACTTTGGGTCCAGACGTAGATATAGATCCCTTTTTTTTC +TTTATTTTTTACTTTTTACTTATTTATTTATTATTATTATTATTATTATTATTATTATTA +TTATTATTATTATTATTGTTTTAAGACAGGGTCTTGCTCTGTTGCCCAGGCTGAAGTGCT +GTGGTGCAGTCTTGGCTTACTGCAGTCTCGACCTCCCAGGCTCAAGTGATGCCCCCACCT +TAGCCTTCTGACTAGCTGGGACTATAAGCACACACCACCATGCTTGGCTAATTTTTAAAT +TTCTTTTAGAGATGAGGTTTCGCCATGTTGCCCAGACTGGTCTTGAACTCCTAAGGTCAA +GCCATCTGTCCCCATCAGCCTCTCAAAGTGCTGGGATTACAGGCATGAGCCATCGTGCCT +ACCAGGTCTTTTTTTTTTTTTTTTTTTTTTTTTTTGAGATAGGTCTCACTCTGGTGCCCA +GGCTGGAGTTCAGTGGCACAATCACAGCTCACTGCAGCCTCCACCTCCTGGGCTCAAGTG +ATCCTCCCACCTCAGCCTCCTGAGTAGCTGGGACCACAGGCACGTACCACCACACCCAGC +TAATTTTTTAAAAAATTTTATGACTGGGCGCGGTGGCTCACTCCTGTAATCCCAGCACTT +TGCAGGGCTGAGGCGGGCAGATTGCCTGAGGTCAGGAGTTCAAGGCCAGCCTGGCTAACA +GGGTGAAACCCCATCTCTACTAAAAATACAAAAAAATTAGCCAGGCATGATGGCACACAC +CTATAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCTCTTGAACCCAAGAGGCGGA +GGTTCTGGTGAGCCGAGATCGCGTCACTGCACTCCAGCCTGGGCAACAGAGTAAGACTCG +TCTCTCTGTCTCAAAAAACAAACAAACAAACAAACAAAAATACTTATGTAGAGATGGGAT +CTCACTATATTGCCCAGACTGGTCTTGAATTCCTGGGCTCAAGCGAGCTTCCCACCTCAG +CCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCACCCCTGGCCTGCACAAATCCCAT +TTTTGCCACTTATTAGGAAGTGTCTTAACCCTGTCTGAGCTTTGGCTTTTGCATCTGTAA +AATGGGGATAATGTTCCATGGACCTCACAAGGACATGGTGAAGAGTAAGAGAGTAAAGGG +AAGTCAAGGACTTAGCCCGAAACCTGGGCAGTGCTCAGTGTCCTGTAATTACCTCTGGTC +TTGGGCTTGACCTTCCCCAAACCACTGCCCTAAATGATCCTTCTTCCATTGATTTTCTTA +AAAACAGGAGCTCTTTTAAAGATATGTAATTGTCTTAAGATAGCTCCAAAGCCATTAACA +GTATTCCAATGAGTTAAAAAAAAAAAATCTGCTTCCTTTGGCGGAGGCGGGGAAAATAGA +CTTCAAACTGTGTTGGAGAAGAAATGTATTGAAGAACGTGGCCTTTGATCCCAGTCTGCC +CAGGTTCATGTCTGCCTGCCATCACTAACTGTGCGACCTTGGGTGAAAAACACTGCTATT +CGTGGCTTTGTTTTTCATCTGTGAAATGGGAGAATAGAGCCCCTGCTTCAAGGGTGGTTG +GGAGAGGTAAGATCGTGAGTGCAAAGTGCTTCTCACCATGGCTGGTGGGCACTAAGCTCT +AGCCCAGTGTTTGTTGCTGATATTACTAAGTGCACCTTGGGCACCTCTTAAAATGGGGAA +GAATGTGGGGTTACAGAAGAGGTGGGGAGCAGAGTAATTATCGTTCTCATTCATGCCCTG +GAGTGCAGGAGTTATCTCCCATCATCCTGTAGTGACCCCACAGATGAGATGATACCACTT +GTAGCCTTTCAATAAGGACAAGGAGACCCAGGTTCGACAGAGTTGGCAACTCTTCCGAAG +TCTCATCATTGGTAGTTGGTGAGGTTGGATTTGAATCCAAGTGTGCCTGATGCCAGGACC +CTAGCTTCTGTTGATTGATCAGTTGATTGATTGAGACAGGGTCTCCCTCTGTCTCCCAGG +CTGGAGTGCAGTGGCATGATCTCAGCTCATAGCAGCCTCCACCTCCTGGGTTCAAGCGAT +TCTCCTTCCTTAGCCCTCTGAGTAGCTGGGATTACAGGCACCCGCTATCACACCTGGCTA +ATTTTTGTATTTTTAGTGGAGACGGGGTTTTACCATGTTGGCCAGACTAGTCTCGAGCTC +TTGACCTCAAGTGATCCACCTGCCTCGGTCTACCAAAATGCTAGAATTATAGGTGCGAGC +CACTGTACCCGGCCCCCTCCTTCTATTTATTACACTAAATGCCATGAAAGTGAATTTTTT +TCTCCCCAAGCCTCCCCATCCCTACCAGACACTGAGAATTATCTTAATGGACATGTGGCT +ACATTCATTTTAGAGTTCGACTTTGGAAATCTCTTAGAAATGTTACTTTAGCTCCTCCAA +CCTGATTTTTTAATTATTATTATTTTTAACATAATAGGCTCTGCTGACCGAGATGATGGA +AAGGTGTAAGAAACTAGGAAACAAGTAAGTATTTTAAGATTCATAAAGCATGAGTTTGAA +AATGGCGTTGGCTGCTATTTTTGAGCTTGGCCTGCTTACCTGGGTATGAGCTGAAGAGAG +AGAGGCAGGACTGCATGGAGGTTTAGAATGCTGGAGTCCGGTTGCCTGGCCTCAGACCTT +GGCTCTGTTCTGTCTTAGCCCTGTGACCTTGGGCCGCTTGCTTGACCTCTCTGTGCCTCT +GTCTCTTCATCTGTAAAACGGGAGTAATAATAGTTCTTTCAACTGGGCGTGGTGGCTGAT +GCCTGTAATCCCAGCATTTTGGGAGGCTGAGGCGTGTGGATCACCTGAGGTCAGGAGTTC +GAGACCAGCCTGGCCAACGTGGCAAAACCCCATCTCTACTAAAAATACAATAACTAGCCG +GGCTTGGTGGTGTATGCCTGTAGTCGCAGCTACTCAGGAGACTGGGGCAGGAGAATTGCT +TGAACCCGGGAGGCAGAGGTTTCAGTGAGCCGAGATCATGACACTGTACTCTAGCTTGGC +GACAGAGTGAGACGCTGTCTCAAAAAACAAAAGAAAAAAAGTAATAATAATAGTTATTTC +CCCATGGGGCTGTGGTAGGTGGTTGGGCTAGGATGAAATTGATCTCCCTGACTCTCACGA +ATATGAGGTTGTCTCTCTGCTTTCCTTTTAGTGGTAGATACATGGAAACAGCCTTGCATG +GGCTTTGTTTACCACTGTGTCCCCTGTGCCTGGTGCCTATAACATAAGATCTCTTTACTA +AGAAATCTCTTGCATAAACTGGCCAGACACAGTGGTGCATGCCTATAATCCCAGCACTTT +GGGAGGCTGAGACGGGTGGATCACCTGAGGTCAGGAGTTTGAGACCAGCCTGGCCAACAT +GGTGAAACCCTGTCTCTACTAAAAATACATAAAATTAGCCGAGCATGGTGGCGCATGCCT +GTAATCTCAGTTACTTGGGAGGCTGAGGCAGGAGAATCACTTGAACCCGGGAGGTGGAGG +TTGCAGTGAGCCAAGATCGTGACACTACTCCAGCCTGGGCAACAAAGTGAGACTCCATCT +CAAAAAAAAAAAAACAAAAAAACCAAAACTCTTGCATAAACGATGTGGATATATATTTAC +AACATGGATCAATATCGTTACTTAATGTTCTGTCTCATTAGTGCACCAGCTTATTGAATG +CTCGCTCTTCTTCTCCTTAAATGAACTGGATCACTTGCTGATCTGTCTATCCACCCTGCC +ATCTAGCCATCCATCCATCTAAACATCCAGTTAATTCAACATTTATTGAGTTGCAGATAT +GTACAGGACACTGTGTTAGTCTCTCCAGTTTACCTTTTTACTCTGATTTTTTGTTTTTCC +CCAACCCTACCGCTAAAGAGCTGTTAGTCTTCCTTCCTGGCAATATATATTCAAAAATTA +AAGCAACTTTGATTGAGGAGAAGCCAGGCTGACTTGGGGATCTGTGTCTTGCAGTGCCTT +GCTGTTGAATTCTGTGATGTCTGCCTTCCGGGCTGAGTTCATCGCCACAAGGTCTATGGA +TTTCATTGGCATGATTAAAGAGTGTGATGAATCTGGTTTCCCCAAGGTAGGCTCTTGACT +TCATGCTCAGTAGGACACAAATAAGCGGTGTGTATCTGATAGCTCTTGAGAGACAGTCCG +GTTTTGGGAACAGCATGGGCCAGCAGGAACACAGGCGAAGGCTCTGTTTCTGAGGAACGC +AATGGAAGATGAGTTAGAGGTTGGGATTGTCAGACACTGTGTGATTGCTATGCTTCAGGC +CCCCATGAGCCCTAAATCTATCAGATTGGCTCACTATGAAGGATTTAAGAAAGACTTTGG +TCTAACATATTTAAGAATATATCAGGCTGGGCACGGTGGCTCATGTTTATAATCCTATCA +CTTGGGAGGCCAGGGCAGGAGGATCACTTGAGGCCAGGAGTTCGAGACCAGCCTGGGCAA +CACAGCAAGACCCCATCTCTACAAAAAATCAAAACTTAGCTGGGTGTGGTGGTGCATTCC +TGTAGTCCCAGCTACTTGGGAGGCTAAGGTGGGAGAATTGCTTGGAGCCCAGGAGGTCAA +GGCTGCAGTGAGCCATGATTATGTCATGAAGCCTGGTGACAGAGTGAGACCCTGTCTCAA +AACAAACAAAAGGATATATCTTCATTCATTATTTATGAAAAACTTTGTCCAGTAGAATAT +TATGGCCCCACATTAGACCAACAGATGGAGCTAACTCTGTGTGAGCCTCTCAGTGTAGCT +GGGGCAGATATGTGTGATAGAACTTTAGAAGGAGGTTGTTGGAAGATTAGCCCCAAGAAG +GATTAAACATTACAACCTTTTCTCTTTTCTTTTCTTTGAGCTTCAAGTTAATTTGATTTA +AAATTTCCATAACATGATGGTTTGACATGTTTCTTAGCATCTTCTTTTTCGATCACTGGG +ATTAAACTTGGCCTTGGCTGATCCTCCTGAGAGTGACCGACTTCAGATTCTCAACGAAGC +TTGGAAAGTCATCACTAAGCTGAAGAACCCACAGGTGAGTGGCCATTTTATTTTTATTTT +TATTTATTTATTTATTTATTTATTTATTTTGAGATGAAGTCTTGCTCTGTCGCCCAGGCT +AGAGTGCAATGGCGCCATCTCGGCTCACTGCAACCTCTGCCTCCTGGGTTCAAGCGATTC +TTCTGCCTCAGCCTCCCGAGTAGCTGGGATTACAGGTGTGTGCCACCACACCCAGCTAAT +TTTTGTATTTTTAGTAGAGACAGGTTTTCACCATGTTGGTCAGGCTGTCTCAAATATCTA +CCCATCTTGGCCTCTCAAAATGCTGGGATTACAGGCGTGAGCCACTTTGCCCGGCCTGCC +ATTTAAACTTTAAATCAACCACTTTTTGTCCAAGTTTTGGCATCTGCTCTTTTAAAAAAT +TACCCTTCCAAGCTGAACATGGTAGCTCACACCTATAATCTCAGCACTTTGGGAGGCTGA +GGCAGGAGGATCACTTGAGGCTGGGAGTTTCAGACCAGCCTGGACAACATAGCAAGACCC +CTGTCTCTATTTGAACTAAAAAATAAAAATTATCTTTTCATTAGTTATACATTTTTCCCT +AAAGAAATCTATTTATTATAATTGTATTATTTGTTTACCTGTAATGGAGAATGGATAGCT +TTAAAGATGTAATTTCTTTGATTTTTTAAAAATTCAATTCTCACAGCCTTAAGATGTGCT +AAAAGTATAAAATTACATGATCATGCGTTCAGAACTGCCATAAAAAATACAACTTAAAAA +AAATGCATAACATTACAGATATTTGAAACTTTATGAAAAATCAGTTAACTTTATAGTGGG +CATCCAAAATATAACAGTTCGTAAGATTTAGGCTTGAAAATATCGTTAGTAGGATATTCC +TAAATAAAAGATCAGCCTTTAAGCCAGTAATTAGCAAAAGGAAATTCCCGTTTCCAACCA +TTGAACAGAGCCAGCTGAAGCCTCCTGTTTGCTGTAATGCATACTATGTTGTACTTAATG +TTAAGATGTTTTCCTTTCTCTTTGTAGGACTACATTAATTGTGCCGAAGTGTGGGTGGAA +TACACCTGCAAGCATTTCACGGTATGTGTGACTGTGGTATTGTTTTTGAAAGAATTAGAT +TTTTTCATGTTTATAATAGTGAATTAGCCTAGTTTAGGTATTGAGGCATTTGACAACGGT +ACTTGCTCTTGTAATTTATAAAAATTGCATTCTTCATAATAAAGCGTGATGGAGCATTAA +TATGTGTACTATAACAAAAAATAACTGTTCCATGTTTACATTTAAGTTTGGAAAATGCAG +CATTACACAAAGTTAAACCATTTTTTTTTTACCATAGGATACCTTAGATGCTTACATGCT +AAAGTGCATTGCGACTGTACATCAGAGTCTAGTAAGCAGCATTTCCCAAACAATTTGACT +GGCATGTAATTTTTTTCCTAAGCAAATATTTCTTTCCCTAGGCACAGACTAGAACCACAG +TTAGGGGAATACTGGGCTTCTCAAAGAGCAGAGACTTTAGAAGAAGATAGAAGTGGGTTC +AAAACCCTTGCCAGAGTAATTTGTTTATTTTAATCAAGTCCTAAAAGTTTTTTTTTTTTT +TTTTTTTTTTTTGAGATGGAGTCTCGCTCTGTCGCCCAGGCTGGAGTGTGGTGGCGTGGT +CTCGGCTCACTGCAAGCTCCGCCTCCCGGGTTCACGCCATTCTCCTGCCTCATCCTCCCG +AGTAGCTGGGACTACAGGCGCCTGCCACCACGCCTGGCTAATTTTTTTGTGTTTTTAGTA +GAGACAGGGTTTCACCATGTTAGCCAGGATGGTCTCGATCTCCTGAGCTCGCAATCAGCC +CGCCTCTGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCACCTGGCCAAGCCC +TAAAAATTTAAGTGTGGCATTGCTATGGTCTGAATGTCTGTGCCCTCCCAAAATTCATAT +GTTGAAATCCTAGCCCCCAGGATGATGGTATTAGGAGGTGGAGCCTAGGTCATGGCAGGC +AGAGTCCTTATGAAGGAGATTAATGCCCTTATAATAAAAGAAGCCCACCAGCCTGGCCAA +CGTGGTAAAACCCCGTCTCTACTAAAAATAAAAAAAAAAATTAGGTGGGTATGGTGACAC +CTGCCTGTAGTCCTAGCTACCCAGGAGGTTGAGGGAGGAGAATCGCTTCAATGTGGGAGG +CAGAAGCTGCAGTGAGCCAAGATTGCACTCCTACACTCCAGCCAGAGCGACAGAGTGAGA +CTCTGTCTCAAAACAAAAATAATAATAAAATAAGTCCTGAGTTGCTCACTGTCCCCTTCC +ATCCCATGAGGACTTGGGGAGAAGATGCCGTTTGTGAGGAATGGGTCCTCACCAGACACC +AAATCTGCCTTGATCTTGGACTTCCCAGCCTCCAGAACTGTGAGAATTACATTTTTGTTG +TTTACAAGCTTCCTGGTTTATGGTATTTTGGTAGAGAAGCCCAAACAGACTAAGCCAAGC +ACACATGCAAAAAAGTGCACGTATCATAAGTTTGCTGCTCAATGAATTTTCACAAGGTAT +GACCATATAATCACCATCCAGAGTAAGAAATAGGAAATAAGTGACCCCGCAGAACCCCCA +GAACTGCCTCTCCCTGTCACAACAGCCTTTGAGGAGGTGAAGGTAGACACCATCCTGGCC +TCTAACACCAAAATTGATGTTGCCTCGTTTTGAGCATTAGGTAAATGTTGGTCCATTGAT +TTTTGTGGTTTTTTTTGGTCCTATTTTTATTTTACATTTTATTATGGAAATGTAAAACAT +ATGCACTCCCTTGTACCCATCAATCAGGAATTATCAATTTATGACAGATCTTGTTTGATT +TATATCATTACCATGTCCCCTGACCCCTGGAATATTTTGAAGCATATCTCAGACATTGTA +TCGTTTCATCTGTCAGTATTTCAGCACACCTGTAAAAATATAAAGATTCCATTGATTGAT +TGATTGACAGACAGGATCTCACTCTGTTGCCCAGACTGGAGTCCAGTGGTGCAATCGTCA +CTCACTCCAGCCATGACCTCCTGAGCTCAGGCAATGCTCCTGCCTCAGCCTCCCGAGTGG +CTGGGACCACAGGCACATGTGGAGATGTAGAGATGGGGTCTTGCCATGTTGCCCAGGTTG +CAGGGTTCACTTCCTTAAACCAAATCTAAATACATTATTCTAAGGAAAAAAGTTACTAAT +TTTTTTTTTCTTCTGTTTTTGAGATGGAGTCTCACTCCGTCACCCAGGCTGGAGTGCAGT +GGCATGATCTCAGCTCACTGCAACCTCCGCCTCCTGGGTTCAAGTGATTCTCCTGCCTCA +GCCTCCTAAGTAACTAGGACTACAGGTGTGTGTGACCACACCCCGCTAATTTTATGTATT +TTTAGTAGAGACGGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAACTCCTGACCTCAAG +CAATCCACCTGCCTCAGCCTCCCGAAGTGCTGGGATTACAGGCATGAGCCACTGCACCCA +GCCGAGTTACTAATTATTTAATATCATCAGTACCAGTCAATATTCTGATTTCCCCAATTG +TCTCATTTTTTTTAAGTTTATTTGTTGAAATCTGGTTGAAAATAAGGCTTCTCCATTGCA +ATAGACATTTTAGGATACTTTTGATGTATAAGTTCTCTCTCAAACTGTCTCCTTCTCTCC +TTCCCCTTTCTTTCCCTGTAATTTATTTGTTGAAGAAATTGGGTCTTTTGCTCTATAGAG +TTGCAAAGACTGGATTTTTCCCATTGCATCCTTGTGATGGTGTCTGGCGTGCTCTTCTGC +CTTTTGTATTTTCTATAAATCAGCAGTTAATTATAGAGACTTAAAAGCCATTCTTAGCTT +GTGGGCCTTATAAAAACAGGCCCTGGGCTGGATTGGGCTGCAGTTGGCTGACTCCTGCTA +TAGGTGACAAAAGTGAACAGTGAGCAGTTAGGTCAGACAGCTTGTAAGGGTGAGCCTGCA +GTCTTCCGCAGTGCTTCACTGTTCTCTCTGCAGGCACCTGAGGGAGGGCCTGGGACAGGC +AGGTGGAGAGAGGCACGGCCGATTCAACCATCACTCTGGGAAAGCAGAGACAATGTAAAG +CCCCAGAACTTTTGAGAAGAGCGTTTAGTCCTGACTAGGTGTGGGGCTGTGGTACTAGAC +CGGGTGATATGAGTGAGATTTCCTCCCTTCCGTTATTTTCAGCAGAATACTGAAATTGAT +TTCCTGGAAGGTGTGTGATATATTCTGAATACGTTAGTCCTTTCCCCCAGGAACATGGTC +AGCAGTTGCCATACAGTGTCTAATTCAGGTTTGGTTCCTTTTTCCTGCTTAGAAACGAGA +GGTGAATACCGTTTTGGCAGATGTCATCAAGCACATGACTCCAGATCGTGCATTTGAAGA +TTCCTACCCCCAGGTAACAGATTTGCATTTCTCATTTCAACATTGTTAGGAATTTTGTTC +TGTTGAATTAAATAGGCGTGTTGTATGGGTCAGGCTATAAAGGCACATAATCCTGTGTTT +GAATCATAGCTCTGCCATATCCTAGCCATGTGCCCTTTGATCAGTTACTTAACCTTGTTG +TGCCCCAGTTTTCTCACCTGTGAAATGGAGATAGTAATAGTGCTACCTGAGAGTTACTGT +GAGGATGAAGTGAAGCCCTCACACAGTGGCCTGGCACGTGGTAAATGCTCAATAAGCGTT +GTCTTCATTGTTGTCACCAGTAAGTAAACTGCGAGTATTTTTAGTTAAATCAACTTTGTT +TTTTCCTTTTTTTTTGAAACAGGGTCTCGCTCAGTCACGGAGGCTGGAGTGCAGTGGTGC +GATCACCGCTTGGCACAGCCTCGACTTCCTGGGCTTAAGCATAATTTTTTTATGTGGAAA +TAAATTTAAGCTTATTGGAAAGTTAAAAGAAAGCTCAAAGAATTCCTATTATTCTTTAAC +CAGATTTACTAGCTGTTAACATTTGTTTTTTTTTGTTTTTGTTTTTGTTTTGTTTTGAGA +CGGAGTCTTGCTCTGTTGCCCAGGCTGGAGTGCAGTGGTGCGATCTTGGCTCATTGCAAC +CTCCACCTTCAATTCTTCTGTCTCAGCCTTCCGAGTAGCTGGGACTACAGGGGCGTGCCA +CCACGCCTGGCTAATTTTTTGAATTTTTAGTAGAGTTGGGGTTTCACCGCGTTAGCCAGG +GTGGTCTCGATGTCCTGACTTCGTGATCCACCCGCCTCAGCCTCCCAAAGTGCTGGGATT +ACAGGCATGAGCCACTGCACCCGGCCAACTGTTAACATTTTACTACATATGCTTTATCAT +TCACGCATTCCACACATATATACATGTATGTGTGTACATTTTTTTCTCAGAATTATTTGA +TAATAAGTTGCATACATTATGTCACATTTTGCTTCTAAAGAGTTCAGTGAGGCAAGGTGT +GGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGAGGGCAGATCACTTGAGT +CCAGGAGTTCAAGACCAGTCTGGGCCATCTCTACAAAAAATATAAAAATTAGCCATGCGT +GGTGGTGCATGCCTATAGTCCCAGCTACCTGGGATGCTATAGTAGGAGAATCACCTTACC +CTTGGAGGCTGAAGTTGCAGTGAGCCCTCCAGCCCGGGTGAGAGAGAGACACGGTCTCAA +AAAAAAAAAAAAAAAACCCACTAATGTGAAATACCCATGTGAAAAGGGTATAAGAGCAGC +TTTTGAAGGGGCTCTCACTTGCTCCCAATTTGAGGATCAAATGGAATTAGAACAGTAACA +GATTATAGCCCATTGAGTAAAATAGGAATCCAAGAGTCCATCCTTATGCTGAATAGATAA +ATAGATGAGCGGATTGAGAAATGTGAAAGAAATGGTAGAATTGGAAAAATCACCATTTTG +TAGCCATCCCAGTAAAGACAAGAATTGTCTTCCTTTAGGTAAGAATTATCAGTGTATGCT +AACCCTGGGAAGAAGAGTTTTGCATGCATTGAGGAGGAGAGAGATTTTGAGAGTTTGATG +AGGAGCAGGATATTTGCATATCTCAAGAGGTCTTCCTACTGAGCAGGTATCAATTGCAAT +GAGGAAAATAGTGACTATACAGCAGAGACAGTGGACAGTCCAGTTAATGAGAGTTCATCT +CACCAATGAGGAGCAAAAGGCCATCATGTGCCTGCAGATGTAGTACCCTAAGAAAGACAC +AGCATCACCTGTATAGCATTTCAGTTGAGAATGCACAAGGGAATGTCACACATGCGCAGA +TTGAGAAGCATTTTATAATTCTTCAGAAATATCACCATGGCCAGGCTCCATGGCTCACAC +CTATAATTCCAGACTTTGGGAGGCTGAGGCAGGAGGATTATTTGAGGCCAGGAGTTCGAG +TCCAGTGTGGGCAACATAGCAAGACCCTATCTCTGCAAAAAATTAAAAAAAGAAAGAAAT +TAGCCAGGTGTGGTGGTGCATGCCTGTAGTTCCAGCTATTCAGGAGGCAGAGCTGGAAGG +ATTGTTTGAGCCCAGGAGTTAGAGGCTGCAGTGAGCTATGATAGCACCACTGCACTCCAA +CCTCAGTGACAGAGTGAGATCCTGTCTCTAATTGAACTAAACTAAAAATAAAATAAATAA +AATGAAATAAAACCCAAAAACCCCACATATATCATTGCCCTAAATGACAAAGACAGACGG +AAGAACTTGTGAACTAACACAGACTAAAGAGACGTGAAAATGGAATGCAGTGCGCAATCT +CAGACTGGATCCTGCACAGAAGATGGAAAAAATAATGTCAGAAAAGACTAATTGAGACAA +TCAACAGCTTGGAAATGGGTGATAGATGAGATCAAATTAGTTTAGATTTCATTATATCAG +TGTTAACTTTCCCAATTTGATGACAGCAAGTGGAAATGTCAGAGAATATGATTATTCTTA +GGAAATAAAAAATGAAGTGTTAAGGGGTAAGGGCATGATTCATGCAATCTACTCTCATAT +AGTTCAGGGAAAAAATAGTATGTTTTGCATAGAGACAACCACAAAGCACATTTGGCAAAA +TATTAAAAATTGATGGATTTGGGTAAAGAATATATGGGAGTTCTCAGTACTATTCTCTCA +GCTTTTCTGCAAGTCTGAAATTATTTCAAAATAAAAAGTTAAAGCCAGGTGAAGTGGCTC +ACGCTTGTAATCCCATCACTTTGGGAAGCCAAGATGGGCGGATTGCTTGAGCCCAGGAGT +TCAAGACCAGCCTGGGCAACATGGCAAAACCCCGTCACTACTAAAAAAATATAAAAATTA +GATGGGTGTGGTGGCGTGCACCTGTGGTCCCAGCTACCCTGGAGGCTAAGGCAGGAGGAT +TGCTTGAGCCCAGGAGGTCAAGGCTGCAGTGAGCTGAGATCATGCCACACTGCATGCCAG +CCTGTGCAACAGAGAAAGACCCTGTCTCAAAAAATAATAATAAAACAAATAATAATAAAA +CAATGATAGAATTGTTTACAAATTCTATCATTAAATGGATGGATAAGTGAGATGATAAAG +TAAATGTATTAAATTGCTGGCTTTTGTAAAATCTAGGTGGTGAATAAATGCGTGTTTGTA +TAATTCTTTCAATATTCTTTATTTTTGAGCATTTTTATAATGAAATATTAAGGGGAAAAA +AATCCTGTCTTTTAAAATCACAGTTTATGTGTAGCTGTGCTTAAGTGTTAACAAAAAATT +TCTTGTTCTAAAGGGATTAGGTGCTTTATGCTTCAGAAACTATTTTAACCAGACAGCATT +GCAGTGTCTTACAATGGTATGCCTTGGAGCATTGTTTATGATGAAGTTTTGAAGTCCTTT +ATTAGTTTTTTGCTTGACTGACCTAGTAAGCTGCCTAATTATGAAATGGGCACATAACGT +TCTTCATGTTCTGTTTTTAGAACATGAGAGATTTTCTTTGGAAATTATTGAAACAGCAGT +TTTTTTAGTGTAAACAAATTGTCAGTACATTTTCTTGATAGCAACCAGAGGTGGAGAGTT +CTATTTTATTTAGAAACCGCATCTTCTTGGCTCTCCTGGACCAAGGCCCTGTCAGCCTTT +CAGTCTGGACTGTGCATCGCAGAGTGAGGGGCGGTAACCATCAGTATCTGGGCATTTTTG +AGGCAGACCTCACAGACTGTGCCACCATCCTTGGGTAATACCTTGGCCTTTAACTCTACC +AGCACACTCTGTCCAAATCCTCTCCAGTGAATAATCAAGAAACACAGGGCCACACGATGA +TGTAGAATAGGGATTGGCCAACTACAGCCCATAGGCTATATGTAGCCTGCCACTTGTTTT +TGTGAATAAAGTTTTATTGGCACAAATTCATTTAATGCACATTCATTTAATGTTGGCAAT +GGCTGCTTTTGCACTGCAATAGTGTTGAGTAGTTGTGGTGGACTGTAGGACGTTTATAGA +AAAAGTTTGCCCACTATTCAAGGAATAACAATAGCTGACATTAATGGAGAACTTTCTAAA +GGCGGGCACTGCACTCAGGACCTTCCACGAACCATTCCATTGAGTCCTTACTGCTTTGAT +CTCCAATTCACAGATGAGGAAGCTGAGACTGAGACTCAGTTACTTCCCCAGGACTATGAA +GTAGGATGTACAGAGTCATTGGGCAAACTCAGCTTGAGACAGAGCCTACCCTAAGCCCAG +TTCACCATTTGTTGAACAATCCAGGCTTACCTTATTGTAGTAATAATTGCAAATTATGAA +AGGTGATTGCCTTTTTAAAAAAAAATTTAGGTTTTCCTGAGAGAATGTAAACCAGAAAGA +AATTTTTAAAAATTAAGTTTTTAAAAATAATATTTTTGTTTGTTTGTTTTACAGCTTCAG +TTAATAATTAAGAAAGTTATTGCCCACTTCCATGACTTCTCAGTTCTTTTCTCAGTGGTA +AGTAGGATTTCTTAATTATCTTTGGAAATTTGTACCTGGCTCAGAGGTTCTCATTGTCTC +AGTAATGTTTTCATGATGCCCCAGGCCAAAAGAAATATTCAGCAGTTCCTTTTATAAAGT +AGTTAAGTCTGATCAACTTAAGTATTTATGTCCTAATAGATTAAGCCGTATTTGAAAAAA +TAATACACAAAAACTGAAAGAAAAATATTATTTCTGTTTCATTCCTTACTTATGGGATAT +GTATAAGTAAGGGCATTACACAACTTCTCAAACCTTCAAAACACTTTGGACAGCCTTCTC +TTACTTTGCTCTTCCACAGTGATTTTCACAGGGCACTTGCTTTTTAATCACACAGCCTAA +TGTTGAAACTATGAAATACATTGACTAGTAGTTGTTTCAGTGTCTGACAGTTGAGATTTA +CCATGATTCCCTCAAAAATTTAAAATATCCTGCGATGTCTGTTCGAGTTTGTTCAGTGCC +CTGGGCAAGTAGGGAATCTAGGTTATTCCCTGTATAGTAACATTCTCTGTCTCTCCCTTC +ACTTCCCTCTTCCAGGTTCCATTTACATGTGCTCACAAGATTGTAAGATTTTTTATTTTA +ATCATAGCAGCTAATATTTATTCGACATATACCACACTCCAAGCACTGTTCTGGGACTTT +ACATGTATTGCCTCACATTAGTTTCATACCACCACGGGGAAGTAGGAGTTATCACTGTAG +TATTGCCTTCTTATCCAGGAGGAATATACATTCCAAGACTCCCAGGAGTTGCCTGAAACC +GCAGATAGAACTGACTGCTGTGTATACTATGTTTTATCCTATACATACATACCTACGGTA +AAGTTTCATATATAAATTAGGCACAGTAAGAGACTGACAACAATAGCTAAAATAGAACAG +TTATAACAATATGCCAGCATTGCTACTCTTGCACTTTGGGAGCATCATTAAGTAAAATAA +GTGTTCTTTGAACACAAAAATGCTGTGATACCATGACAGTGAATCTGATGACAAAGACAG +CTGCTAAGTGACTAACGAGCAGGTAGCATCTACAATGTGGAGACGCTAGACAAAGGGATG +ACTCACAACCTGGGAGGGACAGAACAGTATAGCGTGAGATTTCATTACACTACTCTGAGC +AATGCACAATTTCAAATGAATGGGGCTGGGCTTAGTGGCTCACACCTGTAAACCCAGCAC +TTTCAGAGGCCAAGGCAGGCAGATCACCTGAGACCAGGAGTTCCAGACCAGCCTGGCCAA +CATGGCAAAACCCTGTCTCTACTAAAAATACAAAAAATTAGCCAGGTGTGGTGGTGCATG +CCTGTAGTCCCAGCTACTGGGGAGGCTGAGGTTGCAGTGAACCGAGATTGCACCAGGGCA +CTCGAGCCTAGACAACAGAGCGAAACTCTGTTTCAAACAAATAAAATGCAATAAAAATAA +AAATGAAAATGAATGAAGTGCTTATTTCTAGAATTTTCTATTTAATATTTTCGGATGGCC +GTTAACCGAGGATAACTGACACTATGGAAAGCAAAACCGCAGATAAGGGAGCAACTACCA +TATTCCCACTTTACAGATGAGAAAACTGATGCAGGAAGAGGTAGAGTAACTTGCTTACAG +CCACACAGTCACCGAGGTTAGTATTCAGAGCCAGGCGGTCCAATTTCGAGGCCATCTGTG +AACAGCTCTACTCTGACTCTTCTTCCATTGCTCATCAATATAATCACAAAAAGACTGAAG +TCTGCCTTGCCCAGAAAAGCTTGTGGTCATCAAAGGTTGCCTGGATGGCTCACCAAAATG +TTAACTGGTCCCAGCACCAATCCCTGGAATGCATATAAGTTGTTTTAATAGTAACAGCTT +TTTATTTTGTTTGTTTGTTTATTTTTGAGATAGAGTCTTGCTCTGTCACCCAGGCTAGAG +TGCAGTGGAGTGATCTCGGTTCACTGCAACTTCCGCCTTCCCGAGTTCAAGCAGTTCTCC +TGCCTCAGCCTTCCAAGTAGCTGGGACTACAGGCATGCATCACCATGCCTGGTTTATTTT +TGTATTTTTAGTAGAGACAGGGTTTCGCCATGTTGGCCAGGCTGGTCTTGAACTCCTGGC +CTCAAGTGATCCACCCGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACTG +TGCCCGGCCCAGTAACAGCTTTTTACAAGCCCAGTCAGGTCCTCTCCCTGATTTCAGAGG +AGTCCTCATCTGACCCGACTCAGAGAGATGAACCTCTGTTCTGCTTCTTTGAACTCCACA +GAAAAAGAGACCCACAGATTCCTTCCTTCCAATAACTTGTGTCATTTGCATATAGAGTGC +TTGCTTTATTTATAGGAAAAATTTCTGCCGTTTCTGGACATGTTCCAAAAAGAGAGTGTG +CGGGTGGAGGTTTGCAAATGCATCATGGACGCCTTTATCAAGTGAGTGCCACTGCGTGCA +GCAGAAGCCTTGATTCCCAATGTCCTTGTGAAACCTGTTGATAAAAAATCAGTTCTTGCA +CTTTGAGGCCGAGTGATGTGTACGTATTTCATACAGAAAACCACACTGGAAGGAAAGCCA +CATTAAAAGCAGCAGTCTGATAAAAGTTTGTAATTCGTGTTTAAGAAGACAGAGTAGCAA +GTGTTATCATGAGCCTGGCCAGAAAACCACACTGGAAGGAAAGCCACATTAAAAGCAGCA +GTCTGATAAAAGTTTGTCATTCGTGTTTAAGAAGACAGAGTAGCAAGTGTAATCATGTGC +CTGGCCAGCAGCTCCATTTTACTTTTGATATGTTTTTAGAAGGAGCAGTCTTTTGATAAA +TTCCCTCAAGAGTAACATTTTTAAGGATACAAATCAGGACATACATACTTACGAAGAAGG +CACCGGTGCTAGAAAGGTTTTCATCTTCAGTGTTTAGTTATGTAGCTGACTAATGTGTGA +TCAGTTTTCAAATTTAGCTCTTTAACAAAAAAGAAAAAAAATCAAATTTAGTTCTTTTCA +TTTTTTTGATTAAGTCTGTGTTTCCCAAAACTGCCCGACTGCTAGTGGTACATGAAATAA +TTTTAAGGTGGTGCATGGAAAAAAGGTGTTTTTGTTTTTGTTTGGAGACAAGTTCTCACT +TTGTCATCTAGCCTGGAGTGCAGTGGCACAATTACGGTTCACTGCAGCTTTGACCTTCTC +ATGCTCAGGTGATCCTCCCACCTCAGCCTCCCAGGTAGCTGGGACTACAGGTGTGCCCCA +CTACAACCCAGCTGATTTTTGCATTTTTTGTAGAGATGAGGTCTCTCTATGTTGCCCAGG +CTGGTCTTCATCTCCTGGGCTCAAGCCATCCATCCACCTCAAAGTGCTGGGATTATAGGC +GTGAGCCACCTCGCCTAGCTAGGGTTTTATTTTTATTTTATTATTATTTTTTTAATTTAT +TTTGAGGCAGAACCCTGCTCTGTCACCCAGGCTCGAGTGAAATGGTGCGATCTCAGCTCA +CTGCAGCCTTCACCTCCTGGGTTCAAGCAATTCTCCTGCCTCAGCCTCCCGAGTAGCTGG +GATTATATGCACCCACCTCCACGTCCGGCTAATTTTTTTGTATTTTTTATAGAGACAGGG +TTTCGCCATGGTGGCCAGGCTGGTCTCGAGCTCCTGGCCTCAAGTGATCCACCCGCCTCG +GCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCACACCCGGCCTGTTTTTATTTTT +AGAGTTATATATTGATTTTAAATGTATTAGGCAGTTTATAACTAGTTTAATATGATTTCA +TTTACAATATATTATTTTTTAGGACAGGGTTAAGAAAAAAAAGCTAGTTACTTTAAATAT +TAGGTGTATAGATATGGTTCACTTTGGAAAATTGAGTTTGATATTGCTCAAATGTTTTAA +GCTTTTCTTGTCATCTTTCTAAAAGATTAATTCCTTCCTAAGGATTAATATTAATTCCTA +ATTAATATGCTTGGAATAAATATACCTAATTTACTTACCTAAAGATTTGTTTTAAGAGCT +TGCCCTTTTATATTATTTGAAAAACCAAATGAATAATTTTGCCTGGCAAAATTCGCCTGT +TAAGAACACAGTGACAGGTTTTGGGCAGCTTCAGAAGGTATAAGAAGCATAGTTAAAAAC +AAACAAACAAAAACAGGTTTGCCCTTAGCCCACCTGGTTTAGGAAGGGGAACAGTTTTTC +TGTGATTTTGCAGTTAGGAGAAGTTATCATGTGTATAGAAGAGCAAACTTGTTATTTAAA +GAATTCTGGGCCAGGTGCGGTGGCTCACGCCCGTAATCCCAATACTTTGGGAGGCTGAGG +CAGGTGGATCACCTGAGGCCAGGAGTTCGAGAGCAGCCTGGCCAACATGGTGAAACCCTG +TGTCTACCAAAAATACAAAAATTAGCTGGGTGTGGTGACGCACGTATGTAATCCCAGCTA +CTTGGGAGGCTGAGGCAGGAGGATCACTCCAACCCAGGAGGCAGGGGCTGCAGTGAGCTG +AGGTCACATCACTGCACTCCAGCCTGGGTGACAGAGTGAGACTCTGTCTCAAAAGTTTAA +AAAAGAATTCTGAGACAACCAGAGAACATGGCTCGTTACTGGTAAACTGGGCTGGGTGAA +ATGCCAGCTGGATAATTTGCTGCTTTTCAAGTGTGTACAGTGGATGAAAACTGAATCCAC +TCTTGCAGTGCTGTCAGTGGACAAAACTTTGACTTTTATCTTTAAATGTCTCCTAGGCAT +CAACAAGAGCCCACCAAGGACCCGGTCATCTTGAATGCCCTTTTGCATGTTTGCAAGACC +ATGCATGACTCTGTGAAGTAAGCCATGCTTACAGCTGAAATATAACATGGATTGGGTCTT +AATGCCACCTAATAGGACATTAGGGAATGACTGCTTTAAGCTGCCACTGTGAATAATATT +ACTTTATTGGGAGTATTAAGATTTTTGCTAACGAGGACATTCCAATCCAGGAGAGGAAGG +AGGCTGAGGTTAACCTTCTTGAGAAAGCGACGTGGCAGATGTTGTTAGAAAGGAGTTTAT +GTTGCGGGTAAAAAGCTGGTTCCATTCAAGTGAACTCAAACTCCATGTCTCTTGGAGATT +TCTGAGAGCAGCAGATAGTGTAATAATGAGCTCACTCATCCAGTAATATAGCCTTTTTAT +TTCATCTCTATATTAGCCAATTATTTGAAATTCAAATGAAACTGCTTGAGGCTGAGACCT +ATCCACAGGCATTACCTTTCAGTCAAAGGCTGAATAGTCACTGCCTTCTGGTTTTTGTTT +GTTTATTTTTAAAATATGTTTTCGTTTGACTGTGCTTAGGGCAATTCCTGCTTATTTGTG +GCTGAAATTTTAGTCCCCCAAGAATTTTTAAACACAGCAACTTGATTTACTGGAAAATGT +TACAAGAATGGAGAAAATTGTTTTGGAACTTAACCATCAACAAGATGAACTGTATTTCTT +CTTTGTTTTCTCTGCATTTTAGAATCTTCACTTCCATGATTTTTTGTGCTTTCAAATTCA +TGGGTAGTTACAAAAATCAAAGTGTCGAGGCATTTCATAAAAATGGAACCGGTAGACTTT +AGTTGGACAAAAATAGAAATAAAGACACAAAAAGCATCCAGAAAGGCACTTAGATTCGTG +AGACATTGGGTTTTGGCTTAAGTAAAATAGAATGTTGATTTCTCTCTTGTTAAAATTGTG +CATAGTAGACAGACCAGAAGGTAGGGGTAGGGCAGCTCTTCTTTCAAACATCATCCAGGG +ACCCAGGTTATTTCTGTCTTATTGTTCTCCCAGTCTATCTGGGGTGTTGTCCTTATCTTC +TTCCTGGAAGCTGATGTACCTCAACCATGTCCACGTTCCAGCCTGTGGGCATTGGGGAAC +AGCAGCTTTCTTTTAGGGACAAAGCTGGGAAGGCTCACACATCATATCCCATTGTTCAGA +ACTGTCCCATAGCCACCCCTAGCTGGGAAGGAGGCTAGGGAATGTTGTTCTAAGAACAAA +GTGGGGCTGGGCATGGTGTCTCACACCTGTAATCCCAGCACTTTAAGAGGCCAAGATGAG +TGGATCACCTGAGGTCAGGAGTTTGAGATCAGCCTGGCCAACATGGTGAAACCCCGTCTC +TACTTTAAAAAAAAAAAAAATACAAAAAATTAGCTGGGCGCCTTGGAACGTGCCTGTAAT +CCCAGCTACTTGGGAGGCTGAGGCAGGAGAATCGCTTGAACCTGGGAAGCACAGGTTGCA +GTGATCCAAGATCATGCCATTGCACTCCAGCCTGGGCAACAAGAGCGAAACTCCATCTCA +AAACAAAAACAAAAACAAAAAAGAACGAAGTGGGCATTTGTATTGAAGGACAGTGGGCAA +TCTTTGCCAAAACATTTTCTCCGAGAACAAACCAACAAACAAAAACCTTGACTCCTGTTT +TCTCTGGGCTCTTAAAAATTTTTTTTTTAAATAACTTTGGGGAACTATTTATTCCCCAAA +TAACTATTTATTTAACTATCCAAGTATAATCAAAACTGTAATGACTTTTTCTTATTTATA +TTTGTGTTACATTTTCTATTAAATAGAAGCAACTGAGACCTGAGATTTACTTTACAATGT +ATCAAAAAAATAAGATGGATTGATGGATGGAGAGGGGAATGGATAATTATGTGTAAAACA +AGTAAAATGGTGATGGCAGGATTTCGATGGTGTATGGGTGTTTACTGGAAAATTCTTTCA +ACTTTGCTGTACATTGGAAATATTTCTGTTTCCTTTTTGGGGAGAACGGGGTCTCGTCAT +GTTGCCCAGGTTGATCTCCAACTCCTAGGCTCAAACGAACCTGCTACCTCTGCCTTCCTA +AGTGCTGGGATTACAGGTGTGAACCAGCACACCCCGCTGGAGATTTTTTAAATAAAATAT +TCAATGAAATTTCCCTGAAATACAAAATTTGACATTAGACCTTGCTGCCCAAGTTCCAAA +GAAGTGAAAGTTACCTTTTCTTTTCTTGTTAATAAATCTATCTTGAGAACAGCATATTTG +AGGGAGATGAGAAACATATTTAAATTATGTTAATTGTGATTATGTATTTTTATCAAAGGA +AAAATAAGCAGCCTGTTGGCAGTTTTTTAAATCTAGAAAATGCAAAATGTTCTTACCTGT +TAAATTACTTACCCCTTGTGTATTTTTTTCTTTAGAAACTTTCATCTATTACCTCCGTGT +TAATTATGTACAATTATTGATTTTAGTGCACTCACTCTTGAGGATGAGAAAAGAATGCTG +TCATATTTGATTAATGGATTTATAAAAATGGTAAGTATTAGGGAAGAAGTTTCAGTGCAC +TTGGAAGTGTGATGTAATTGTTTATCCTTATGTTGGCGAAAGCAGTTAACATTATGTTCT +CTGGTGCTTTTCATTCTTAGTGAGATAAAATGAAATTAGAAAACATCTTACATTAGCCAG +GACTCCCCTGGGGGCAAAGAGAGCCAAGACAAACTGGCTTAAGAGGAAAAAGGTGGGGGG +CGGGAGGGTGATGGGAGGAGGGATTTCTTGGCTCATGTGACAAAAAGTCCAGGGGCTGGA +ACTCTCCAAAGCAGCAGCCGGGCTCAGGGTCTCCGGGATGTCATCAGGACCTGCCTTCCC +TGTCTTTTTTCTTTTTTTTTTTTTTTTTGAGATGGAGTCTCGCTCTGTCGCCCAGGCTGG +AGTGCAGTGGCGCGATCTCAGCTCACTGCAAGCTCCGCCTCCCGGGTTCACGCCATTCTC +CTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCGCCCGGCACCACGCCCGGCTAATTT +TTTGTATTTTTAGTAGAGACGGGGTTTCACTGTGTTAGCCAGGATGGTCTCGATCTGCTG +ACCTCGTAATCCGCCCGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACTG +CACCCAGCCCCCTGTCTGTCTTTAGCCCTGGGCTCTGCCCTGTTGGCCTCCGGCTCAGCT +GGGCTTGCCCCACCAGAGCTCCAGGTTTCCATCCCCCCCAGCTCTGCAGCCCAGCAGGTG +GGATTCCAGCAAAGTCCTGGGATTGAGTCTCTTTGGATTAACATGGGTCGTGGCCCCAAG +CACACCTGGGTGACCTGAGTCAGGAGGGCCGAGAGTGGAAAGAAGGTGTGTCCTGAAGCA +GCTGATGCAGATCATCAGACGGTGATGGAAACTATGCCGGGCAGGCAAAACGCCAGATAT +CCACTCCCCATCTGTTTTACTTATCTACTGCTGAGTAACAGCTCATCCCAAAACTTAGTG +GCTTTAAATAACAGGGCTTTTTTTTGCTGTTTTTTTTGGGGGGGTCGAGACAGGGGTTTC +CAACTCCTGGTTTCAAACAATCCTCCAGCCTTGGCCTCCCACAGTGTTGGGATTACAGGC +CTGAGCCACTGCGCCCAGCATGAGTTTTTTATTAGTTCTCAAACTCTGCGGATCAGCTTG +GTAACCAGGCTGCTACAGGGAGTGTGGTGTGGCACTGGCGTGGCACGATTGGGCTGGAGG +ATCCACAGTGGCCTTGTTCCCTTCTCCAGGGTTTTGGTGCTGGATATGGGCTGGGGCATC +TTGGTTTTCTTCCATGTCCTCTCTTTCTCACCACTGTTCTCAGTCAGTGATTCCAGTTGA +GCTCTCTTACTTGGTGCTGCCTTCTATGAAGGCACAGACAGAAGCAGCAAGGCATTTTAA +GGCCAAGGCTTAGAAATCACACAGTGAGGCCAGGCGCGGTGGCTCACATCTGTAATCCCA +GCACTTTGGGAGGCTGAGGCAGGTGGATCACCTGCGGTCAGGTCGAGACCAGCCTCACCA +ACATGGTGAAACCCTGTCTCTGCTAAAAATACAAAATTAGCCGGGTGTTGTGGTGCATGC +CTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCGCTTGAACCCGGGAGGCAGA +GGTTGCGGTGAGCCAAGACCATGCCACTGCACTCCAGCCTGGGCAACAGAGCAAAACTCT +GTCTTGGGAAAAAAAAAAAAGAAATCACACAGTAAACCCCTGCCATATTCTACTGCAATC +TGTGGGTCAAAGCAAATCACAGTCTTGAGGGGACCCAGTCTGGAGGGGAAGAGGCTCTGC +CTTTTGATGGGGGGTAGTCCACAGAGACATTGCAGAAGGGCAAGCACAGTGGGAAGGTTT +CCTGCAGCCTCCTTTGGGAACATCCCACCATTATACTATCCCAGCCTGAACAGTCTTCAC +CTTCATTCTGGGTGCTCTAAGCCAAAACACCAACTGCTGCAAATATCTTCTATTTTAATA +GAAAAGTCAGGACCAAAGCTGACTGAGATGAAAATGACGAGATCACTTTGAAAATAACCT +TGAAATTCTGACTTGTTCAATAGTGCGGGTTGATTAGTCTACCTGACTCTGCGGGTAAAA +TATCAATTTTGATGAAAATTCAGGATTAGCCTTTCAATTCCCGTGTTAGGAAACAGACAT +ATGGATTTTCCCAAGTCGCTCTCCTTTGCCCTTGCTTTTTGTACTCATCATGTGGTATTT +ATCTTTTTACGGCATTGTCTGAAAGTTACCAAGTTATTATGGAAAAGAATATAAGGAAAT +CAGATATGAAACATGATAGCTGTAATGGAAATGGCAATGTTAAACCTCATCTGGACAAAA +ATGATTGATGTACAGTAAAGTTTTTCTTACTAACCAGCTATTCATAAATTTGAAGAAATA +GGAGAAGAGAGGATGTTTAATGGTGGAAAAACTTCCATCTATGGCTTCTGTAGCCACCAG +TGAGCTGCCAAGGTTGGGTCCCCATCAGGAAGCAGAAAGGTGTGACTGTTACGATGGCAA +ACCTTCTGACAAGGGGCCCCCAATAACCACATTTATGTTCTGTGAAAAGGCCACAGCTGA +CAAACAATATCCCATTATTCCCTTTCCAGTGGTTTCCTTCAGAGTCTGGAAAATTCTGCT +TACACTCTGAGCTTCTGTTTTATACCCTTCGACTTCTTAGGTTCTAGTCCAGTGCCCACG +TCATAAAGATGAGGTGGCAATAATAATATTTCAGTCATACCATGTGCCTGCGTTCTCTCT +AAAAATACCACTGTCCCTTTCAGCGTCTTTCTCCTTGATTCTAGGTTTCCTTTGGCCGTG +ATTTTGAACAACAGCTGAGTTTTTATGTTGAGTCCAGGTCGATGTTTTGCAATCTGGAGC +CTGTTCTTGTGCAGTTGATTCATGTAAGTATTTTCATTCATTAGTTTCTTCTCTCAGTAA +ATATTTATTGATCATCTACATCCCAATCATTTATTTTGATTTTATTTTATTAGAGACAGG +GTCTCACTCTGTCACCCAGGCTAGAGTGCAGTGGCGCAATCATAGCTCACTGTAGCCTTG +AACTCCTGGGCTCAAGCAATTCTCCCTGTCTCAGCCTCCTGAGTAGCTGGGACTACCAGC +TCAAGCCACGATGCCCAGCTATTTTAAATTTTGTTTTGTGTTGTTTTTTGAGAGATGGGG +TCTCTGTGTTGCCCAGGCTGGTCTCAAATTCCTCACATCCAGCATTCCTCCTGCCTTGGC +CTCCCAAAATGCTGGGATTACAGGAAAGAACCACTGCGCCCACCCTTAATCTGGGTTTTT +TCTGGTCCTATTTTGTTACTCTTCTCTATGGTATGAAAGGTGGTTTCTCAAAGGTTAATA +AACTTACAACTTTGGTTTTATTGATCTGTTTTTCTGTGAGATTTGCATTTTCCCATTTCT +GCCTGCCAGCAACAGAGGTAAGTGATTTACAATGATTAGTTACAGAAATCTAACCAGAAG +GAGCCCCTTCTTACGTAACAAGAGGTTCCCTACTTTCTTGGATCATGGCAACTCTCAGTA +ACTTTTTATGGTGCCCTCAGACCAAAAGAATTAATAACAGCCCTGTTTATTAAGAAGTTA +GGTTCAGGCTGGATGTGATGGCTCACACCTGTAATCCCAGCACTTTGGGAGTCTGAGGCT +AGCAGATCACTTGAGGTCAGGAGTTTGAGACCAGCCTGCCCAATATGGTGAAATGCTGTC +TCTACTAAAAATACCAAAGTTAGTCAGGCGGGGTGGCAGGCACCTGTTGTCCCAGCTACT +TGGGAGTCTGAGGCAGAAGAATCGCTTAAATCTGGGAGGTGGAGGTTGCAGTAAGCAGAG +ATCGCGCCACTGCACTCTACACTCTAGCCTAGGCAACAAAGGGAGACTCCATCTCAAAAA +AAAAAAAAAAAAAAAAAGTTAGGTTCAGACAACTTAAGTATTTATGTCTAACAACTTGAC +AGCCATTTGAAGAAAGTATATATATAAATTGAAAGAAAAATAATACTTTTTTTTCCTTTT +CTTTTTGAGCTGGAGTTCTTGCTTTGTTGCCCAGGCTAGAGTGCAATGGTGCGATTTTGG +CTCACTGCAACCTCCACCTCCCGGGTTCAAGTGATTCTCTTGCCTCAGCCTCCCGAGTAG +CTATAATTACAGGCACCTGCCACCATGCCCGGCTAATTCTTTGTATTTTTTAGTAGAGAT +GAGGTTTCACCATGTTGGCCAGGCTGGTCTTGAACTCTTAACCTAAGGTGATCCACCTGC +CTCGGCGTCCCAAAGTGCTAGGATTACAGGCATAAACATCAAGCCCTGCCAATTTTTTTC +TTAACCATAATTAGTAATGATGGGTGTGTACTTATGAAGCATATCACAGCTTCATAAAAT +TTTGGAGTTAGATTGGTGATGCTATTCTTATTTCTTGTTTTACATTCACTGTTTTTTACA +TTTATTCTTGCACAGCGATTAAACTTGCTTTTGATCACAGTAGCCACGAAAAACAAGTTT +TACAAATATATGATGTGGCTATAAGGGATGTAAAGCAGTCCATCATCAAATCAGCCTTGC +ACCAGTGCTTTTTACAACGTGCAACAAACAAGTATTGCTGTTTACAATGTGCGACAAACA +AATATTCCCTAAAAAACGGTGGCGCCCCTGTGAGTTTGCTGCAGCACCCCAGGGTGCCAT +GGTGCACCGTTTGGGAACCACAGGTCCAAACTTTTTATATCTGTGGAAGGGTTCCCTAAG +GCTCTTTCATTATTTCATGTCTATTCAAGGAGAATAACTTTCATATGTATTTGTTTGCTG +GTTAGCAAGTTATTTAGCACAACTAAACTTAAGACCTAAATTTAGAAACTATCTGGAAAT +CAGGGGAGGTAATAGTATCCACCCTGGGATTATGAAGCTTAAGTGAACCAATGAATGTAT +AGCTCTTAAATAGTGCTTGGAACACTATTAGTGATGATGTGGCTACTATCATTATTGTTC +TTATTGTTGGTACTGTATAGCTGAATGGTGTGGTCTGATTGTCTAAATGGTGTGCTTTGG +AGTTGTCTCTTAAGATTTCTAAATTCTTAAACTTTGGTGTGGTAGGATTTCTGGAAATGG +AGTAAGTGAGCCCCAGCTATTCATTAAGCCAGAAAATGGTCACTAAAATGCTGATCAAAA +GGCATGACTGACGTAGCCAACACTGCCTTTTGTTCTACCCTCTTGGAGATGTTTGCTCAA +GCCATGATTGGATCAGGCCTGATGACCCCTTTGGCATTTCAAGGTTTAGTGCTAACCAGT +CTTGGTCCTAGAAAGCTTGTTCTCATTGACCTGTATGTAGTTAATGTTGAGATCTCTATG +GAAGACACTCATCTGAATCGGCCATCGCTTCATTACCATTTCTATTTTATTAATAAATTC +AGAGTGTGAACCGGTTGGCAATGGAGACAAGAAAAGTAATGAAAGGAAATCATTCCAGAA +AGACAGCTGCATTTGTCCGGGTATGTTCTTAAGATAAGGACTGTTGGACCTCGAACTCCA +GTGGGCTGTTTAGTTTGCAGGTTACTAAATTACATTTCCCAGAAAAAGATGAGTATGTCA +TGATAAGAATGGTTTAGTATTGATTTTTCAGATTAATTTTTCCCTGTATCTATGGGATGA +GCCATTTTCTAATGTTTTCAAGAGAAATGGTTAAATGAGTCTGAATTTTAATACGTGTTG +TGGGGAAGGTGAATGAGCGATGGATCTGCATTTTTATGTGCCAGCTGAATTAGCTTTCAT +TTTCTCTAATATACTAATATAAGACATATTTTATAACATTATAAAATATAAAATAGTTTT +CTAATATAAAAATATGTATAATAATATTGTTCTTGTAACTGAAAGGCCTTTTTTCCTCTA +GATAATAATGATGCCCAACTTTGTTTTTGTTTTTCTTGAGACGGAGTCTTGCTCTGTCAC +CCAGGCTGGAGTGCAGTGACGTGATCTCGGCTCACTGCAACCTCCGCCTCCCAAGTTCAA +GCGATTCTCCTACCTCAACCTCCTGAGTAGCTGGGATTACAGACGCGTGCCACCATGCCC +AGCTAATATTTTTGTATTTTTAGTAGAGATGGGGGTTTCACCATGTTGGCCAGGCTGGTT +TCGAACTCCTGTCCTCAAGTGATCTGCCCGCCTCGGCCTCCCAAAGTGCTGGGATTACAG +GCGTGAGCCACCACACCTGGCCTGATGTTAAACTTTGAAAAATCATTTTCAGCTTCTTGA +AGCTGAAAATTTTATCAGATGTGATGCTGCTCAAAATTTATTTAGCTATTCATTCATTTA +TTTATTTTTGGAGACAGGGTCTTGCTCTGTCACCCAGGCAGGAGTGCCGTGGCACCATCA +TAGCTCACTGTAACCACCATATCCGGGTAATTTTTTTGTTTTTTGTAGAGATGGGGCATA +TCACTAGGTTGCCCAGGCTGGTCTTGAACTCCTGGCCTCAAGTGATCCTCCTGCCTCAGC +CTCCCAAAGTGTTGGGATAACAGGTGTGAGCCACCGCACCCAGCCCTGCTCAGAATTTTA +AGAAAGAAATATGTGTCTGTGTTTTTAAACATGAAATTATACTGAAAAGATTACAGTAAA +AAATAAGCATCCTGGCTCTGCCCTTTGTCACCTTGCTTCTCTTTCCTCAGTTAGCCACCT +CAAACTCTTTAGCAACTGTTTCTAATTACCTCCATATTTTTAAGCAATTGGTTTAAACAG +CTGTCTCTCAATTTATCAATGTTAGGTGTTACGTATTTACTTCCCGTGATGGTGGGTGAG +GATTTGTTTTTCCTGCATTATCACTCACTCCCCTCACACCCCTGTCCTCCTAGAGGGTCA +TCAGAGCAGAGTTGTACAAGAGGGGAAAATGGGGCTCAGAATGTGGAGATTCACTGTTGT +AAGTTTCTTTCCTTGGAAATACATGAGGGATGAAAACAGGAGTATGATTCTGCCACCGTT +GCACTGCTAGCGTTAATGTTTCTTCCCTTCTCCTAGGCCTGTGTTGCCTACTGCTTCATC +ACCATCCCCTCCCTGGCGGGCATCTTCACACGTCTCAATCTCTACCTGCATTCTGGTCAG +GTGGCCTTGGCCAACCAGTGCCTCTCCCAAGGTAAGTCCATCATTCTCTCATCTCGGGCA +CTCCCTTGCTGCTTAGGAAAACTGACTCAGGTGTGTGCGTATGTGTGTAGAGAGAGACAA +AGATTTCTTTTTTTAGAGACAGAGTCTCACTCTGTCACCCAGGCTGGAATGTAGTAGTGC +AATCATAGTTTCCTGTAACCTCGAACTCCTGGGCTCAAGCAGTCCTCCTGAGTAGCTGGG +ACTGCAGGCGCACACCACCACACACAGCTAATGTTTTTATTTTTATTTTTTATAGAGATG +GAGTTTCGTTTTGTTGCCTGGGCCTGTCTTGAACTCCTGGGCTCAAATGTTCCTGCTTCC +CACCTGGGCTCAAATGATCCTCCCAAAGTGCTGGGGTTACAGGCCTGAACCACTGTGCTC +AACCAAGAGAGATTCCTTTAAGGAGGAAAGAAAAAAAAAGATGAATAAATGATGAGTTTT +AAATTTGTTTCTCCGCTAGGAAGCACATTGGACACATATGCATTTATAGAGTCAGACAGA +TCATAGAGCACAGATAGCTTCCTGTAAGAACCTTCTTAAATCTGTCTAGGACAGACCGGG +TCATGCAGCTCAGACATCCTGAGCTCAGCACACCTGGAGAAAGTGAGACATGAGGACTGC +TTCACAGTGGTAGATTCATGTTTGTTTGTTGTTGTTGTGGATGTTTGTGTGTTTGAAACC +CCAGAAACACACAAGTACCATCTAATCTGTGATAGAACAAATACCCTACAGTTTGCTGTT +ACAGATAGTTTCTGCCCAAGACTGGTCTTTCCGTACTAGACACCAAAGCCATCCATTAGG +CAAGGATGCTCAGGATCATTTATTTGGGAGAAGGTGATCTCAGTGATATCAGAAGAGTGA +TGTGAGATGAGACAGGGAAGGAAAGGAAGCCAGAAAAATAGGAACCATTGAACAGGTCGT +TCCTGTGGGCAGCTGAAGCTCATTCCCATCTGGGAGGTGTTGTCAGACAGCCAGTGTTTC +TCCATCTGAAGGGCAAGGAAGACAGGTGATTTTCCCTTTATTCTCATCTGTCATTGACAG +AGTGCTGCTTCTAGGATATTAACCCCCTGGCATTCTGGCCTGCTCCACACTTGAGCCAAG +AGAAGGCACTCAGGTGGAAAGCCCAAGTGTTTGCTGCAGGACACCCTGGTTACCTACTGC +AACGGTGTACGCCAAGGGCCTGCAGGCAGGTTAGCAACAGGGTACCCACCCTGCAGGCCG +TAACACAGAGGGTAAAAGAAATCTTTACGCGACATTTATGGAGTGTTTGTTATGTGGCAA +GCCCTTTGCACAAGTTATCTCATTTCATCCTCCCAGAAGCCACATGGGGCCGGTGCTGTG +GCTGGTGCCTTATTACCCAGGTGAGTAAACTGAGGGAGAGAGTGGCCAACTAACTTGCTT +GGGGTAGATCCACTCCTGAGTCACTGAACCAGCTCTCAGCCCCTGATCTGTCTGGCTCAA +GGCCATGCCCCTTCACCACTGCATTGACTGGGAAGCCTAAAGGAATGCCGGGGCAGTTCC +ATAGCGCCATAGGAGGTGGACTGAGGTTTTCAGTGGTGGTTCTTTTCCTGACACAACTGC +ACAGATTATGCCAAGGCTGGCGCCTCACCACTTGTTGCCATTGTCTTCGTAGGGCATTCT +GGGCCAATTGGAGAGTGATCACTTCTCCATTCTTTGAACCACTGCCATGGAAGTTTTGGG +GATCATCTGTGTCATGATTCAACTGGAGCAGCTCTGGGCAGTGAAGTCTTCATACATGGT +TACTGCCCAGGAACCTTTAAAACTCGGCTTGGTTTTGCTTCTAACTCATGGGGGACTTCA +GTAGCTTCTGAGTGCAGCTGAACACTTGCCTCTTGATTTCCCCTGTGAGCTGGTGCCTGC +CCACCTCCATCCTCAACCACCTGCATCCTCATCTCCCATTTGCTTTAGTCACACAGGCCT +GCTTCTGTTCTTTGAACACACTCAGTGGTCTCCCAGTTCAGAGCCTTTGTGGCTTTTTTC +CCTCTTTCTACAATGATCTTTCCCCAGATAGTTGTATTTTTTTTGAATTACAAGGCAGAT +GGTGAGAACAAGCCACAGCTCCTTACGGAGGCCTCTGCTGGCCACTCTAGCTAGAGTAGC +CGCCCTGCCCTACTCTGTCACCCCTGCAGCATCAACCTCATTATCATTGTTGCACACTCC +ACAATCCGATGCTTTCTTACTGTGTTTGTTTACTTGCTTATTGTCTCTGATACCCCCTCT +CCCCACTAGGACAGGCACGTGTCCTCACTAGGACAGGCACGTGTCTTCATTGTGTGTAGG +TCAACATGGAACTTTCTCCTACTGCTTGCTTTGGTAAGAATGATGGGTTATCGGGAGGCT +GAGGCACAACAATCGCATGAACCTGGGAGGTGGAGGTTGCAGTGAGCCGAGATCGCACCA +CTTGAGCAACAGAGCAAGACTGTCTTGAAAAAAAAAAAAAGAAAGAAACAACAATGGGTT +AGTGAGAAACAAAACAAAAATTAACAGTCACCACCAAAAACCTAGTGATGCACAGGATGA +AAATTAGAAGACGCTTCCTTGGATATTAGAAATTTTAAATCTGCTTATAAATGGGTTCCT +TCTTTAAAAGCTCAGGAATGGTGGACCTAGGTAGGCACACCTGAGTTGGTTTTACCTGCA +ATACTAGGAACAAATTGTGAGCTGCAGATACCAAAGCTATGACACCACTTACCAGAACTG +CAAGGGGAGGCTTTAGAAGCCTAGATCTTTCTTCTTCCCATGTTATAAAATCAGGACCAT +GGATCTGAATGTTGTGGATCTTGGGAAATTTATAATTAGATCCCATGTAGGGCTTTATGA +TAATTTTTTTTGAAAAAGCAAAACAAAAATTCTCTACCTGGATAAAGGTATCCCCCTTAT +CAAAGATTTGGTGCTCCCAAGAACTGTTGAAGGAGAGCTGTAAGTAGTTTCTCCCTGTTG +TGCTTCCTATAACGTCCTCGGTCCCCACTGAGGGACAACTGGTGTGAGAACAGCCCCATA +TACTGTGCATGGATAAAGACAGCATCCTCGGTGTCAGGACTCTGGGCTCCTTGTCTGTCT +CCCCTGTCACTTTTCAGCTACTGCAGGAGAGTGGGAATGTGGAGTCCACTTCATGTTTAA +TAATTTATCTGATGATTTTTACTCAAGTCTCTAAATGCTGTGGCGCTAAACCTTAAAAGC +CTATTATTTTTCTCCTGAAAGCCACAGGCAGCAATTGCTGGCCAAAATAAATAATGCATT +CAATTACTGAGAATGAGAAGGCTAAATATAAATTAAATGAAGCTCATGGAAATGCGCTGC +TTTTGTTTGCCTCCCTAAACATCCTCCCCTTGCAGCTGGTTATAAAATGTCCCCGTCCCT +CCAGTTCATTTTGTTGCCTCCCTTAATCCGGCCTTGGTTGTATCTTCTTTGGCAGGCTGT +GGCTTTCCCAAGGCTGGGTCCATCCCGACAAGTAAACTCCTGTTGAACCCTCAGGCAGGC +TGGCGCAGGATGCTGATGAGGGCTTGTTGCAGGGGAGGCCTGGTTCTGTTCCTTTGTACA +CACCGGTGCTGTGCATAGACTGGATTGTGCAGGGATTTGGCACGCATGCTTGTGCCCACC +ACCCCAGAGTATTTAGGAGAAATGAAGGACTTGCAAGCTAGAGATTTGGTCGATCAGATG +CTTCTTAACTGGAGATGGCCTAGCAATGTCTCTCTTTTCTTTCAGTCCCTTCTCTAGGTA +ACTTCTTGCCCTTGTTTGTCAATGGCTCTTTCTAGAAAATTATTTCCAGGCCACAGCAAG +AGCAGGTTCTTTTCTCCTTTATTTTTACCTTTGTTTCTTTATCTTTACAGTTTATAATCT +AGAAAAGGTACGTGTTTTACGGGCTAGGCGTGGTGGCTTATGCCCATAATCCCAGCACTT +TGGGAGGTTGAGGTGGGCGGATCACCTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACA +TGGTGAAACCCCGTCTCTACTAAAAATTAAAAAAATTAGGCAGTTGTGGTGGTGTACTCC +TGTAATTCCAGCTATTCAGGAGGCTGAGGCACGAGAATCGCTTGAACCCAGGAGGCAGAG +GTTACAGTGAGTCAAGATATCACCACTGCACTCCAGCCTGGGCAACAAAGCGAGACTCTG +TCTCAAAAAAAAAAAAAAAAAAGAAAGAAAAAAGAAAATGGGGGCATTTTACAATGGAAG +TATGTTTAAGGTGGGTCTTAAAAGAAGAACATGTGTTTATGAGAACATGGGAAGGGAAGA +AGGAAGGATTAGCATTCCTGGTTGAGTAAATGGCCTGAGCAAAGGCATGGAGATGTGGAA +TTACATGATGTATTTGGCCAACAGCAGAATGTTGGGATGAGGCCCTAATTAGTACTGACT +TTCAAGTCTTCTGCTTGCATTGGTCCCAGTCCTGACTCTGCCACCTACAAGCCAGGTGCT +CTTGGATGACTCGGCCTTTCTGTCCTGTTTCCCCATCTGTAAAGTGGAGACGATGACAGT +GGTACCTATCTGTTGAGTGTTAAATGAGAAAATGGCCTTAGAGCACTTGGCCCACCGGCA +CATAGTAGCTGCTTAGTAAGTATTATCTTAGTATAAACATCTCTCAAATGATGAAAGTAT +GCCATGGGTTTTAGGAGCTAACTGTATACAGTACGTTGAGAGCTGTTTGATTTTATAGTT +AGAAAGCCAGATTATTTTTCATATGCAAAGCATTGGGGAAGCTGTAGGAAACTTAATCTT +TGTTTTGAGACAAACTGATGAATTATGCTAAAAAGACTTGCGGTTCCTCCAAAGCTGAAA +CAAGATAGAACAATTAAAGAGAGATAGTGGTCAAAAGAACTTGTTTTTTTTTTTTTTTTT +TTTTGAGGCAGAGTCCTGCTCCGTCGTCCAGGCTGGACTGCAGTGGCGTGATCTCTGCTC +GCTGCAACCTCCGTCTCCCAAGTTCAAGTGATTTTCCTGCTTCAGCCTCCCAAATAGCTG +GGACTACAGGCGTGCACCACCACACCGGGCTAATTTTTGTATTTTTTAGTAGAAATGGGG +TTTTACCATGTTGGCCAGGCTGGTCTCAAACTCCTGAACTCTGGTGATCCACCTGCCTCA +GCCTCCCAAAGTGCTAGGATTACAGGCATGAGCCACCGTGCCCAACCAAGAATGATTTTA +TTATCATTAATAATCATGCTTTTCCCACCTTCTGTAGGGATCTCCCCTGTTCTTTTAGAA +CTTACTTTCTTTTATTTTTTGCATCTTCATCCTTCAGAGCTGGGTTCATATGTCATGTCT +TTAGAAAAACCATCCTTGGCCTTCCCATTTCTGCAGATAAACAGAAAGTTAGGTCAGGTC +ATCCTGTACGATATATTATCCGCTCACCTGTGCTTTTTCTCCATTATGCTTATCACTGTT +ATTTAACAAGTAAATATGTAAGTAGTTGTCTGCTTTTCCCCCTGTAAGCGCATCACCTCC +ATGAGGTCCTGTCTGTCTGGTTTACTCAAAAAGTTTGAGATTTTGGAGCACTTTGGATTT +CAGATGAGGAATGTTCAACCTGTATATGGAGCCCCTGGCTACCACAAACTGTAATGGCTA +ATGGAAATAGCCAGGGCCATGATGTGGGAGAGAAAAATTATTTTGCATTTCCTCTTCCTG +GAGAGTCAAGAATGGCTTGTGAAGGAGAAAAATAGTTTTCACACATTTACCAGGTCTTGG +CGATTTATGTTTAAGTTCCTATTTAGTTTAGTTAACAGAACATCCTTTGAAGAGTGTTTG +ATTTGATTGTTTTCTCCAACCCTGAGGCCTCTTTGGTGAATGCAGACAAAGTAGGTTATT +TTAGTTGGAACAGTTCACAGCAGGGCAGATGGCATCAAGCTTGTCGCCCACGTTCACATC +TGTCCACACATGATCCATCCATCTTAGGGAGTGTCAAGGCCTGGGAAGGATGGCAGCTGC +TCATGGAACCCACAGAAAAAGGGCACGGGCAAGTCTCCTCCTGACAATCCCTCAGACCCT +TATAATAGTTAAATTATAACCTGCAGTTTCTTCCTCCTGTCAGTATTTTCTGGTCATCTT +TTACATGCGGCCCACTGTGCCAAGCATTGTATGGGCAACAGGAATGCACTTAAAGAGACT +ACAGGCTGGGCTGGGCGCGGTGGCTCAGACCTGTAATCCCAGCACTTTGGGAGGCCGAAG +TGGATGGATCATTTGAGGTCAAGAGTTCAAGACCAGCCTGGCCAACATGATGAAACCTCG +TCTCTACTAAAAATACAAAAATTAGCCGGCAGTAGTGGTGTGTGCCTGTAATCCCAGCTA +CTTGGGAGGCTGAGGCAGGAGAATCGCTTGAGCCTGGAGGGCAGAGGTTGCAGTGAGCCA +AGATCGCACCACTGTCTCCAGCCTGGGCAACAGGGTGAGACCGTGTCTCAAAACAAAACA +AGAAAAAGAGACGACAGGCCATTCAGGGAGAGCAAATCTGTTTACAATTATTACACTAGG +CGACACATGATAAAGCTCATGCACTATGGACATAAAATGTGCTTGGGAATTTTAGAGCAG +AGAGAATTAACCCTTGACTTGAAAGAGGAAAAAAAAAAAGAGGTGGCATTGAAGAGCCTG +GAAGGTCAGGGAATATCTTGTTATTATACTGAAGTAAGGTGTATGGCATTCTAGGTTGAG +GCCTGGAGGCTGAGAAAACAGTACGTCTGGAAGGAATGAGGAGGAGATCAAGTTAAGGTG +ATAGTTGAGGGCCTAATTGTTGAGAGGTCTGAACTCCTGGCAAAATAGTTTTATTCAGTA +CGTATTATTAGGTAGGTGGTTTATCTTTATTTTGCAGCTGGAGAAACTGAGGCTCAGGCG +TGCTCAGGAACATCCAGCTAATGAGTGGCCTTATCTGGATTTAACCACTGTGCCTCTCTA +TATTAGGTTAGTTCTTCTATATCATAACATAGGGTTGTATTTCTAATCCCAAGTGCACGT +GGTTGCTGGAGGTCAATTATTACGGATTGAGCATTAGATAAACTAGGAAACAAAGAACCA +AAATTAAGATAAGGAATACCTAATCCTTTCTGCTTAGGGAAATCTAAGCCTACTTTTCAC +AGAGACAATACGCAACCTCAAATGAGCTACTGCATGGATGAGAGAAAGGTATGTCATCCT +GTAGTATCTCCGAGGTAGGAGTTAGGTAACACATGGGCTGAGCATGCTTGGCTCAGTGAG +AGAGCCCTTGACAGTTCAGAGAGTAGAGGGAGGGAGAGAGTGCAGGAGCCTTCTGATGGT +ACTACCGAAGCTAAGAAGTAATTTATATGTCCCAAGTGGATTTTTCACATTAAGTGTTGA +TATTCAGAATGAACTTAAAAGGCATTCTGCATAAACCAGGTGGCAAAATCAAAGTTAGAT +TAAGCCATCATTGATAGCAATTAAGCATTAATGTATAAGGTATTTAATTGTTCCTGGAGA +TTCATATTTCTTTACATCTTGCTTTATGTACATATCAAAATAGTGGCCCCTAAGTCCTCA +AACTTAGCTGTTGGAATAACAAGTTCTATTACAAAAACACAGGCTAGTAATAGATAGTGG +TAAATCTCTATCAGTGACTTGCCTGTGGATAACTTGGCCACTGAGACCACAAGGCTTTGC +CAAAGGCACCCCATCACTTGGTGGCAGCACATCTTCATTGCAGGCAAAGTTTTCAGGAAG +AAGATATGTCTGGATGTTGCATTTTATGTGGTAGTTTCCATGATATTGATATTGTCAATC +CAAACCTAAACTCATACGGAGATAGAAAATGTTGAAGATGGGTAAAGATGTTTTGCAATG +GGGTTTGTATACCTTGAGAGAGAGTGATGATTTTTATAGCCAGAACCCTGCTTTACTAAT +ACACATTCAAGAGATGGGAGTCTTCAACCCTTGGAACATCTTGTCTTAAGAACTTACGAT +TTTTGGCCGGGCACGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGACGGT +GGATCACTAGAGGCTAGGAGTTCGAGACCAGCCCGGCCAACATGACAAAACCCTGTCTCT +ACTAAAAATACAAAAATTAGCCGGGCGTGGTGGTGTGCGCCTGTAGTCCCAGCTACTCGG +GAGGCTAACAAGGCACGAGAATTGTTTGAACCTGGGAGGTGGAGGTTGCAGTGAGCCATG +ATTGCACCACTGCACTCCAGCCTGGGCAACAGAGTGTGACCCTGTCTCAAAAAAAAAAAA +AATAAAGAAGAAATAATGGTTTTTCTATTCTTCGATCTTCCTGGGCTAGGACAGCTGTCA +GTCTGAGTTTCCTGAGTTACCTAGGAGGGTAGTTGGATTGATGGATTGATGGATTGAAGA +TCTAGGAGTGAAATGAATTAACTTTGAGGTTTTGTTCAGCCTCAGGAGTTTATGACTGAC +GAGTGGTAAAGATTTCCATTAGCACTGACCTAATGCATTATTGAAAAAAAGCAAAATGCC +AATTTTGAAGGTGGGATGGGTTATCACTTCTTGACTGTCACTTATGATTCATGTATTGAC +TCATTTTCCATATCACCAATGCCAACCATACAAAAGGTTGCATTTACTCTTGTAGGTCCT +AGTTAAGTCTGAATTCCTTTTATCATGTATTGAGGGTGTTTGGTGAGATTGTCCTGTATC +CAGTTGAAAATCTAGGCAATCTGTATTTTAAATCTTAATGACTTTCACTATAAAAATTCA +GAATGCTCATTTGAAAAACTTCCAACCATACAGAAATGTAGGACTCTTAAAAAGTAAAAA +GCCCTGAGATAAAAGTCTCCAATAATATGCTGTATCTCCCCACCCCACCCCCAAATCTGC +TGTTGTTAACAGTATGGACATCTTGATTTTTTTCTTTTATATATCCATTTTAAAATATTC +ATTATTCTTGTATGCTCTCTGCCTCTCTATTCTCCTTTCTCCTTCACTCTCCATTTATCT +ATATTCTTATATATATATATATATATGTAGTTCTCTTTCCCCCTTAGCAATAAATGGAAT +TATGTCTTCTACAGTGTTTTTCATAAGCCTTTTTTGGCTTCTCTGTAAATCTTGGTGTCA +ATCAGTACCCTCTTTGTAATGGCTGTTTGGTATTCTGTTTCTTCTTTTTTTTTGGAAGTG +CTACAAATTATTTCTTCAAATGGCCCCCCTCTATTTTTTTTCCTCCGAACTCCTGTTGAA +AAATATATGAACTCTTTGCAAGTTTTTGCTCTGGCAGACAATAAATAACCTGCATCTTAA +TTCTGAGCACTTTGAAGCTTTCTGACAGTTGCCCAATTGGTATTTTAGCCTCTTAGAATG +TGGAACTCTATTGTTCAGACAGAGGCGTATTGAAAGCCTTGGTACACACAACAGATGCCA +GTGGGGCTCCTCAGGTGGACATCCCAGTGGGAGGTTACTGCCCCTGAATTATCTACAGGA +GCTCGAAGAGGCCCCAGAGCACGATATGGAGCTTTTTAAAGCCTTGAGAAGAAGAACCCT +TGCAAGTGGACTGACTGGGGAGCTTCAAGCCTGAAGTCTGACTCATTTCATGGAGAAGCT +AATTAGAGAGGACCCTTCCCGCCATCCTCACGGTGCAGTGCAGAACAGCATCCCTGGTTG +GTCCCCACAGTGTGTGTATCACCCCTCAGCTTGGTGCTGTGCCTTACACATACAGGGAAC +TGGGGTGGCTGCCCCTTAGAACAGCAGGAGTATTAAGAGTCCATGCAGTGTGTGGCCCTG +TCCCTACTTCCATCTCCACCTTGTCCTACTCTGGTTAAATAGGGAGTACATTGTTTTGCC +ATATTTCTGTTTTATACATTTCTAGGACTGAACATTTTACAGCAAACTTGTATTGCCTTT +GTATGTTCAAGAAAAATTATTTTTAGAAATTTAAGCCTGGGCAACATAGTGAGACCCAGT +CTGTACAAAATATGAATTAAAAAAAACTTAAAAAATCAGCAGGCATGATGGCGCACGCCT +GTAGTCCCAGCCACTTGGCAGGCTGAAGTGGGAGGGTTGCTCGAGCCCAGGAGGTCGAGG +CAGGAGTGAGCTATGACGGTACCACTGCAATCCAGCCTGGGCAGCAGAGCAAGGCCCTGT +CTCAAAAAATAATAATAAAAATAGGCCAGGCACGGTGGCTCATGCCTGTAATCCTAGCAC +TTTGGGAGGCAGAGGCAGGCAGATCACCTGAGGTCAGGGGTTCGAGACCTGCCTGGCCAA +CATGGTGAAATGCCATCTCTACTAAAAAAAAAAATACAAAAATTAGCCAGGTATGCCAGA +TCTGACCTGCAGACCCTGACCCAGTGACGGATAAAAGACTGACACGGATATTTTGCCTGT +CAGCATGGCTAAGAGGCTCTGCTGCCTGACTACAGCATTGGCCTCCATAAGCCGGCAAAG +TTCGCATTTATTTAGTACAGATTAAATGACAAAGGTCTCGAGTAAACACCACTAGAAGGT +AATTAACATTGCCGACCTCCTGAGTAGAGAGCAGTCATACACCCACAGATGATCAAAGGT +CGGTCTTAGGACCACATGAGTAAACAAGCTATTTAGATAAAACCCCCCACATTCACTTAC +TATTTGCTCTTTTGCTATCAACTCAAGGTAAAGAGGATTAGGCTGCCTTCAGCCATAACC +CTTTCCTAAAGCTTTTGTAAAACCTTCCGGCCTTCCAAGAAAGCTTGCGTTTTTCCTATA +ATTTTCTCTTACAATTTCTGACATCACCCTAACCGAGCTCCTACAGGGGCATGGTAGCAG +ACGCCTATAATCCCAGCTACTTGAGAGGGTGAGGCAGGTGAATTGCTTGAACCCAGGAGG +CAGAGGTTGCAGTGAGCTGAAATTGTACCACTGCACTTCAACCTGGGTGACAGAGCAAGA +CTCTGCCTCAAAAAAAAAATAATAATAATTATAATGATAATAATAATAGGCCGGGCACAG +TGGCTCATGGCTATAATCCCAGCACTTTGGGAGGCAGAGGCGGGCAGATCACCTGAGTTC +AGGAGTTCGAGATCAGCCTGACCAACATGGAGAAGCCCCGTCTCTACTAAATATACAAAA +AATTAGCTGGGCATGGTGGCTCATGCCTATAATCCCAGCTACTCTGGAGGCTGAGGCAGG +AGAATCACTTGAACCCAGGAGGTGGAGGTTGTGTTGAGCCAAGATCATGCCATTGCACTG +GGCAACAAGAGCAAAGTCTCAATAATAATAAATTTCAATTAAAATTCCAAGACAGTAGCC +TATCAGTAAGTGAAAAAATTGGTGTCCATCCTCATCCACCACTCCAATATTACACCTAAT +AGTTTGGCATTTATCTTGCCTGACCTTTCTATGCATCTACATAAGTTTATATACTTTTTT +TCCTTTGCAAAGATAGGCTCACACGTATACAGCTGTGTGACTTTTTGTCCTTTTTTTTTC +TTTTTTTCCCCCGCCACCCTCCCCCCCGATTTTTTGTATGTAATATGTCATAGATGTCTT +TATACCTCAAATATACCTCAAAACATATAGATCTGCCTTATGCTCTTTATTAGCTATATT +ACTTGCTTGGTGCAACAGTGCAGTAATTTCTTTTTTTTTTTTTTTTTTTTTTTTTTTTAC +ATTTTGGAACTTTAAGCTGTTTTCACTTTTTCTTCAAATGATCTTAGAGTTGATATAAAG +ATATCTTCATCCAACAGGAATGATTGACCCAATCATTTATAGTAGCTAGGCAGCATGAAT +AATCAAAACATACAGTTTACCTAGCATCTTCAGCTAAGCCCTTATTTTCAGCTTCTGTCT +GCATCTCACCCTTTCCCGCAGCTATTTGCTTGTGACATATATTTTGGAGTCCATCTGTGG +GGTTTTAATGGCTTTGTGTTCTGAGTGTTTGATTTCTTCCTGTCCTTGCGGAAGTTTCCC +GAATACCGTGTTCTTTCAGTGGTCCACAGACCTTTTGAAACTACTCAGGTTGAGAACAGG +AGAGCCTGAAACTTCAGATGGAAAATGTCAAATGTGATATTTTGCCAGTGAGCATCCCTG +GCATTTACTCGTCATATATACAAAATAATGAGGTAGTCTGTCCCCATATTTTTAGCAAGG +ACCCCAACAATTCTTACAATAGAGCAGTCCAAGAGTACTACAGTGCTCTTACAAATATGG +GGGCAGTGGCTATGTTTATGCAATTTTTCTTACTATGAATACGGGGACGGTGGCTGCGTT +TCTGGAGTTTCTCTTACTACGAATATGGGGATGGTGGCTGTCTGTGTTTGCTCTCTGCCC +AGCAGAGAGCAGTGCCGTGAGATGCGTCAATTGCTGTGTGGAAAGAACCATAGAATGCTG +CTCAAAAAAGTGAAGTCCCTTTTTCAAGAAAAAGGGGTCTCAAATACAGTGACTGTAGTG +TTGGGTCAGCAAGACCTGAGTGGGGTTTTTCTGGTTTGGGTTTTGCCTTTAAGATGGGAT +ATGCAGTGATTGTTCTGAGATACTGGAAATATAAGCAGAAAAAAAAAAAAGGTATATGGA +AAAGAAACATGGATGTCCCAGCAGGGAACGGTGGCTCACGCCTGTAATCCCAGCACTTTG +GGAAGCCAAGGCAACCGGATCACCTGAGGCCAGGAGTTAAGACCAGCTTGCCCAACATGG +TGAAACCCCATCTCTACTAAAAATACAAAAATTAGCCTGGCACGGTGGCATGTGCCTGTA +GTCTTAGCTACTCGGGAGGCTGAGGCAGGAGAATCGCTTGAACCCGGGAGGCGGAGGCTG +CAGTGAGCTGAGATCACATCACCGCATTCCAGCCTGGGCAACAGAGCAAGAGTTCATCTA +AAAAAAAAAAAAAACAAAAAAACATGAATGTCCCATGAACCCCAGAGGACTTGGATGAAG +GAAGCCTAGTCCGTGTACTTGCTGCTTTTCCCCTTCCTCTAGTGGAACCAGGACAATATA +TATTTTTTCCTTTTCTAAAAAAATTTTTGTGGGTACTTAGTAAGTGTATATATTTACAAG +GTACATGAGATGTTTTGATTCAGGCAGGCAGTGTATAATAATTACATCCTAGAGAATGGT +GTATCCATCCCCTCAAGCATTTATCCTGTGTGCTACAAACAATTCAGTTATATTCTTTCA +GTTATTTTTAAATGTACAATTAAATTATTGACTAGAGTCACTGTGTTGTGCTATCAAATA +CTAGGTCTTATTCATTCTTTCTATTTTTATTTTGTACGCAGTAACCATTCCCACTCCCCA +CCATGCCCCACCATTACCCTTCCCAGCCTCTGGTAACTATCCTTCTACTCTCTGTCTCCA +TGGGTTCAATTGTTTTTGTTTTTAGCTCCCACAAATAAGTGAGAACATGCAAAGTTTGCC +TTCCTGTGCCTGGCTTAATTCACTTAACATAATGCCCTCCAGTTTCACCCATGTTGTTGC +AAATGACAGAATCTCCTTTTTTATGGCTGCATAGTACTCCATTGTGTATATGTACCACAT +TTTCTTTATCCGTTTGTCTGTTGACGGACACTTAGATTGCTTCCAAATCTTGGCTATTGT +GAACAGTGCTAAAACAAACAGGAGTGCAGATATCTCTTCGATATACTGATTTCCTTTCTT +TTGGGGGTAAATCCAGTGGTGGGATTGCTGGATCCTATGGTAGCTCTATTTTTAGCTTTT +TCAGAAACCTCCGAATTGTTCTCCGTAGTAGTTGTACTAATTTAACATTTGCACCAGCAG +TGTGTGAGGGTTCCCCTTTTCTCCACATTCTCACCAGCATTTGTCGTTGCCTGTCTTTTG +GATAAAAGCCATTTTAACTGGGGTTCGATGATATCTCATTATAGTTTTCATTTGCATTTC +TCTGATCAATGATGTTGAGCACCTTTTCATATGCTTGTTTGCCATTTGTATTTTTTTTTT +TGAGAAACATCTATTGAAATCTTTTGCCCATTTTTAAAATCTGATTATTAGATTTTTTTT +CCTATAGAGTTGTTTGAGCTCCTTATGTTCTGGTTATTAATCCTTTATCAGATGGGTAGT +TTGCAAATATTTTCTCCCATTCTGTGGGTTCTCGTTTCACTTTGTTGATTGTTTCCTTTG +CTGTGCGGAGCTTTTTAAGTTGATGTGATCCCATTTGTCCATTTTTGCTTTGGTTGCCTG +TGCTTGTGGGGTATTACTCAAAGAGGGGACAATATTCTTTACTACTGGGAATCTGAGTTC +TCCTTTTTCTGTAGGTCTTTAAAAAAAAATCCGTTATATCTTAAATGAGCTTCCATAGCT +CTTAATAGCTACAAAACAAAGTGTTACATGAAGTTGACATGATTATTCTGAACTTTAAAC +TATAAGGATAAACTGCTGTCACATGGGGTAGGATTTGATTTCTAATTACTTAAGATAAGA +TTGAGAAGTCTCCAGACAATATTTTCTATATGGGGCAAGTCTTCTGAGGATAGAACTAAA +AATCTGCTTTGGAACCCTGCATGCCCCAACCTTTAAATAACTGTTTATTTTAGCTCCGTC +CTTTAGAGTGGAAACTGGGCGGGGTGGGTGAGAGGAGCCAAGTTCTGGGGACAAAGCTGC +TCTCTTTTTAATGAGGCATAATAATAGGCACATTCTCTGGGCCAGTCAGTAACAAACACA +TAAATAGAAAAAAATGGTCTTTCAAGTTGCTCTGAGCAGAATTTGCATTCCCACTGAGAA +CCTTGTTTCATGATATACTTACTTCACTGTGGGACTGCCGGAGGACTAAGGAAATGAACT +GCTTAAAGATAGGGCCTAGGAGATCCTGTGGGTTCCATAAGTAGGGCCATGTTTTTCTTT +CTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTCCTTT +CTTCCTTTCTTCCTTTCTTCCTTTCTTCCTTTCTTCCTTTCTTTCTTTCTTTCTTTTTTT +TTGAGACAGAGCATTGCTCTGTTGCCCAGGCTCGGCTCACTGCAACCTCTGACCGACGGG +TTCAAGTGATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGAATTACAGGCATGTGCCACCA +TGCCCAGCTAATTTTTGTATTTTTAGTACAGACAGGGTTTCACCATATTGGCCAGGCTGG +TCTCAAACTCCTGACCTCAAGTGATCGACCCACTGGCCTCCCAAAGTGCTGAGATTACAG +GCGTGAGCTACCGTACCTGGTTGGGCCATGTCTTACTAGTGGTCACAAGATAGAAGACCC +TGCAGGCTCTGACCCTTTCTGGAAGGTTTCTCTATCAGAACGGACATCAGGTGGCTTTTC +CTCAAGCCCCATATTTAATGTCTCTCCCCAAAACAATTGAGATAAGTGGATTCATAGACC +AAAATACGTAACAGGCTTAGAAAATAAGTGTTGGCCCAATGCGGTGGCTCACGCCTGTAA +TCCCAGAACTTTAGGAGGCCGAGTCAGGCAGATCGCTTGAGCTCAGGAGTTTGGGACCAG +CTTGGGCAACACGGTGAAACCCCATCTCTACAAAAAATACAAAAATTAGCCAGGGATGAT +GGTGCACTCCTGTAGTCCCAGTTACTGGGGAGGCTGAGGTAGGAGGATGGCTGGAGCCCA +GGAGGCAGAGGCTGCAGTGAGTCGAGATCACACCGTTGCACTTCAGCCTGTGCGACAGAG +CAAGACCCTGTCTGGAAAAAAAAAAAAAAAAACCAGAAAAAAAAATAGTTGTTAATTAGT +ATGATTATGTTGGTCTCATTGCCACAGTTTATGTTGTCAACGCTTTCTCTCACTTTTTTT +TCATCTGTTTGTCTACCTGCCCATGACAGTACCCTGTTCACAGTTGGGGCTTAATAAATG +TGGAAGGGGTTTGAGTTTGGGGTTCAGGAGACAGCCAGGCAAAGAAGCTTCCAGAGCAGA +GCTAACTTGACTCAGAAAGCTTTACAAGGAGTGTCTTTCTGTGACATGTTTTTTTTCCCT +CTCCTTTGAAGAAGGAAGAGATGGCAAAACTCCACCATCCATCTTCAGACACATACTCTT +CTCATTAAACATAGGCCTTTCTTCCCAGGAAAGTGAGCATTTGCTGTTGCATTTGCCCCT +CTGGTGTGCTGGCCGGTGTTCCTGTTTTAATTCAGGATGCTGTTCACCCCTACAGTGTTC +TCTTTGCATCACTGGAAGTCGTTTTGGAGTGGAAGTCCATTTGGACCATGAAAACATTTG +ATCTTGTCGGGTAGTTTAAAATTTCATTTGTCAGGTCAGTGTTTTGATTGTTTTGACCTT +GAGGCTTTTTCTCACGGTCAATACCTTGGCAGTTTTAGAAAGAACTTTCACTCCCTCTCC +GTCTTCCCCTCCACCTCCCATCCTTCCTGCTCTCCCTCATCCCTTCCACCCCGTCTCCTG +TTGTGCACACACATTCTCTCTCCACTCCTTTTCTTCCTCTCTTACTCCCTTTGAAGTCTT +CTTGTTTTACAGATTTTTTCATAGCTCTTTAAATATCTTCATTTCCCAAACGATTCTATG +GAGCTGATGTTAATCAGAAGCCTTTAAGCTGAGTGTGTGTGTGTGTGTGTGTGTGTGTGT +GCTGTGTTCCTTCAGACATTTTGATGGCTATTTAACAAAAATGGTGTGCACTAGAATAGA +TTCAAACTGACCTGGGTTTGAGCTGCAGCTCTACTACCAACACTGGAACTTCATACACAG +GACACTGTTGCAGGATGAATTGCTTCTCTTTCCTTCCCTTATTTCTCGTCTGTGAAGTAC +ACGTGTTGACAGCACCTTCCTCGCACTGGTAGACATGAGAATTCAATGAACCAATCCAAG +TTGAGCTTTAGCCCAGGCAACTGTCATTTCTAGACTTTTTACAAAAATTTGCGACCTGCT +TTTTTCACTTAATAATCTAAAGACAATTTAACAGAGGTTCTCTGAGCTGAAGCAGTGCCC +TGTCAAGCAAATATTCCTCCAGCTCCATCATGGTTTGCAGAAACCTTCTGCTAGGACCTG +CCCTCGGCATGGCCTGGCTTCTACCTAACTCTCAGGACTGGCCTTCAGGCCACGTGAAGA +AGAAAGCCAACTAAATTTCCCAGAGTTCTAATATACTGACTTTTATCTTCTGTCTTGCAG +CTGATGCTTTTTTCAAAGCCGCTATAAGCCTTGTTCCGGAAGTTCCAAAGATGATTAATA +TTGATGGGAAGATGCGGCCATCGGAATCGTTCCTTCTGGAATTCCTCTGCAATTTCTTTT +CTACTTTATTAATAGTTCCGGTACGTTTCCTCAGCAGAACCGCAGGACATGTCTTCCTTT +CACCTGCCTTATAATATTATATGTGTTCTTAGGCCTAAAACTGCAGGAACATTCTATCTA +GTATCTTTGTGTTGGTTTTCCAGTTAGGTATTTGAATTGCTTAATGAATTTTCTATTCTT +GCTGGGTGGGGATCATACTATAATAGTAGAGGTGAGGTACTATGTCAGCTCAGGCTGCTA +TTACAAAGTGCCATAGACTGGGGTCTTAAACAACATTTATTTCTCAGAGTTCTTAAAGCT +GGAAGTCTGAGATCAGGGTGCCAGTCTGGTTGAGTTCTAGTGAGGACCCACTTCCAGGTT +GCAGACAACCATCTTCTCTCTCTTTCTGTCTCTCTTTTTTTTTTTTTTGAGATGGAGTTT +CACTACTGTTGCCCAGGCTGTAGTGCAATGGCATGATCTTAGCTCACTTCAACCTCCACC +CCCCAGGTTCAAGTGATTCTCCTGCCTCAGCCTCCTGAGTAGCTAGGATTACAGGCGCCC +GCCACCACACCTGGCTAATTTTTGTATTTTTAGTAGAGATGGAGTTTCACCATGTTGTTC +AGGCTGGTCTTGAACTCCTGACCTCAGGTGATCCACCTGCCTTGGCCTCCCAGAGTGCTG +GGATTACAGGTGTGAGCCACCATGCCAGGCCTTTTTGTGTGTTTGTTTAGGAGTCTTGCT +CTGTCACCCAGGCTGGAGTGCAGTGGTGCAGTTATAGCTCACTGTAGCCTTGAACTCCTA +GGCTCAAGTGATTCTCCCGCCTCAGCCTCCTGAGCAGCTGGGACTGCAGGCCCATCTTCC +CGTTATGTCCTCATGTGACAGAAAGAAAAAGCAAGGGCAAGCTCTCCGGCCTTTTGAGCA +ATTGGTCCTCTGGGACCTAATTACTACCCAAGGGCCCCACCTCCAAATCCCATCACATTG +GGATTAGGGTCTCCGTGTATGAATTTGCAGGGGGATACAAATATTTAGTCCACTGCACTC +TCTATACTGCCAAGGCAGAGGTGTCGCCCAGTGGGGAAGGGCACAGGCCTCGGAACCAAG +ATGTCCAGCATGGAATCCTGGCCCATCCTTCTTCCAGCTCTGCGTTCTTGGGCAATAATA +TAACATCCCTGGGCTGCAGTTTCCTTGTCTATAAAATGAGGATAAGAACTGTCACTTCTG +GGTTGCCATGAATATTAAGTTAGTGAGTACTCACAATGTCAGAACCATGCCTCTGCACAT +AGTAAACTTTCTAGAAAGCACTAAGAAGGTGGCGACAAAGTTCTTTTGATGGCAAATAAC +AGAAACTAAACATAGCAGAAATTAAGAGGGGCATTGTTGGAAGGATGCTGGGTTTTTCCT +GGGATGGAAGAGATGTACAGCCAGGCTTGAGTTGGAAAGAATGAGGCCACTCCCGGGACC +CAGCAGGAGGAATTCCTGGACCCTCCCTAGCAAGGGTCCTTATAACTTGGAGTCCATCTA +CTCCCTGGGGGTCTGGCAGAGTGACATGAATTTGGATGAGGAAAATGACAGCTTTATTTT +AACAAACCTCTGAGTGAAATTTACCTTTCACTCGATGAATTACAGGCAAAAAGCCACAGT +AGTAGTAGCAGTAGCTGGGACTTTGTCACCAAAAGAAATCAACAGATATGTTCACATCAC +ATTTCAGATGTGAAAGATATTTCAGAAGATTGTGTATGTTCTTCTTCCTTTCAAAGCACA +GCAGTTATTAAGCCCATTGCTAGAGCTGTTAATGCATTCACAAAGAAGCAACAGATTACA +GTATCACAGAAGCATTGAAAAAATATTTTGCCAGCTGTATTTTAGTGTAATTGGTTTGCT +TTTTAGTCTTATGTGTTTTATTTGCTGCATTAAAAATAATATTCCAAGGACTGGGCACCG +TGGCTCATGCCTGTATCCCAGCACTTTGGGAGGCGGAGGTGGACAGATCACCTGAGGTCA +GGAGTTTGAGACCAGCCTGGCCAACATGGCACAACCCCGTATCTACTAAAAGTACAAAAA +TTAGCTGGGCATGGTGGTGGGCACCTGCAATCCCAGCTACTTGGGAGGCTGAGGCAGGAG +AATCGCTTGAACCCAGGAGGCGGAGGTTGCAGTGAGCCGAGATTGCACCACCGCACTCCA +GCCTGGACAACAGAGCAAGACTCCATCTCAAAAAAAAAAAAAAATGTATTCCAAGGGCCA +GGCATGATGGCTCACTCCAGTAATCCCAACACTTTGGGAGGCTGAAGCAGGTGGGTCACC +TGAGGTCAGGTGTTCGAGACCAGCCTGGCCAACATGGTAAAACCCCGTCTCTACTAAAAA +TACAAAAATTAGCCAGGAGTGGTGGCAGGCACCTGTAATCTCAGCTACCAGGGAGGCTGC +GGCAGGAGAATCGCTTGAACCTGGGAGGTAGCGGTTGTAGTGAGCCAAGATTGTGCCACT +GTACTCCAGCCTGGGCAACAGAGCAAGACTCCATCTCAAAAAAAATAAAAATAGTATTCC +ATGGAGTGTATAGGCTTCACCTGGCTGCCGCAGGGTGCATGGCACAGAACAGATTAAGCA +CCGCTGGTAGAGCTTAATGTGCATGGGAATCTCAGACTCTTGTTAAAATGCAGATTCCTG +GGGCCCCTCCCAGAGTCTCACTCAGTAGGTTGAAATAGGCTCACAAATCAGCATTTTTAA +AATCATCTAATTGTTTTATTTTGAGAAGGGGTCTTGCTGTATGCCTAGGCTGAGCTCCTG +GGCTAAAGTGATCCTCCTGCCTCAGCCTCCCAAGTAGCTGGGCCAACAGGCATGTGCCAG +CCACCACGCCTGGCTAATTTTTTTTTAATGTTTTATAGAGGTACATTCTCACTACATTTC +CCAGGCTGGTCTTGAACTCCTGGCCTCAAGCAATCCTCCTCCCTCACCCTCCCCAGTACC +TGGGATTACAGGTGGGATCAACCATGTTTGGCAAATGGGCATTTTTAAAAGCCCCCTTCA +GTGATTCAGGGGTAAGTGGTCCTAGGACCATATTTGAGAAACATCACCCTGAACTTGAGC +CATAAAAGTGCCTGAGCTCCAGTGGATCCAGGTTCCTTTTTGGGGTGATGATATGTTCCA +AAATTGACTGTATTGATGATCGCACAACTCTGTGAATATCCTGACAATCACTGAATTGTA +CATTTTAGCAGGTATACTGTTTGGCATGTGAATTATATCTCAGTAAAGCTGAGAAAACAG +AAAGTGACTCAGCTTCTGACTCTCCCTGTTCAGATTCCAAGTCTTCAGACAGAGGGGAGC +GAGGTCAGGAGGCCAGGCTCAAGGACTGCAGACATGGCTTCAGGATGGGGGCCTCTTGTT +GTCCTGCAGGGAGGATAGGCGGCACCCCAAGATGGGGCAGCGTGCACTGGCATTTTCTAG +AGCCCCTTCACTTGACACTTGATGTCACTGTTTTCAGATCTCCATATTAGTACTCTGTAA +GTTTCTCTCTTTGGGTAAGCTAGTTATTTATCAAGTGAGAAGGCAAAAGAAAAAAAATCA +GGGTTTTGAATTAAGCAGTTGGTAAAAGTGAGAAGGCAAAAGAAAAAAATCAGGGTTTTG +AATTAAGCAGTTGGTAAAAGTCATTGTTTATTGATTAATCGGGATGCATTCAGCATCTGC +AGGTTAAAAATCACTGGAGCCTTTTTGAAAAGCCTTCTCAGATTCAGAAGCTTCTGTTCA +GTCCTGACCTGAAGAGTTCATAGCGCTGAGACTTTGGGAAAGTTTTATAACTCCTCAGAG +CTTCAGTTGTCACCTTTCTGAGGTGTCATCACAGTGCCCACCTCAAATGACTCCTGTGAG +GGTTAAATGAAATGATAGCTGGGAAAGTGCTTTGTAAACCTGAAACTCTGTCCCTGGGAT +TACAGATTGATGTCTGGAGGGCAGATCCAGCCGGTAGACATGTAGACACTTGCTGGCTAT +GTCCTGATGGAGAACATTTGGAATGAGTTTCCTACATTTAAAAATTGGTAGATCACAGAA +AATCCCAGATTTGCATCTCCCCTTGAAAAATCAGGTCCTATCACGTGGGGCCCGCATCCT +GCGACCTGGCCAGTTGGCTGCAGCTGGGTACCAGCTGCCCTGTGCAGGCAGCGTATGCCT +TTCTCTCCAGTTTTCCTGGGTACCTCTGGACCCATTAACCCCATTTCTGTTGTCCACTTG +GCCCCTTAGGCATTTGTGGAAAGAGCTCCTGCTCTCAACAGATTCATTATTCCTTGAACA +GATTTGAGTTATTTATTCCTTGAACAGATTTATTATTCCTTGAACAGATTTGCGTTATTA +TTCCTTGAACAGATTTGAGTTATTTTTCCTTGTAGCATTGCATGTGTTTTAGCTGGGGTT +TAGTAATGATATGAGACAAAGAATAGCTGCAGTTCACAACACCTCACTAGGTGCCCCATG +CCTTGCTAACGCCACTCATTAATACTCACTTCCTGGGAGTCCTCCACCCAAGCCCCCCAA +GGTAGGAATCATTGCACCTTTTTCACTCATGAAACCTGAGCCAGAGGGCCCTTGCAATGT +GCCTGAGGTCACAAAGCTTATAAGTAGCAGAGCTGGGATTTGAACCGAGGGCTACGCTAT +TCCAGAGCCTGTCCTGCATGACTGAAGCCGGAAACGTTTGCAGTGTGCCTTATTTGCTCA +AGTTCATTGAGCACTAGCAACCCTGTATCCCTCCTTGTGGGACGCGGCATTAGTAACTAC +TCACAGATGCTACAGGATGTTTATCCTGAATAGCCAGGGCTAAGAGCTGAATAAACTCTC +AGGTGATGGGATGCGCCACACCTGAGCCATGCCCATTATGAGTAGATCTAGCATTAACAA +GACTCCCACATCTCACTTCTACCTGGTTCAGTTTTTTTCTTTTTCTTTTTTTTTTTTTTT +TTTTTTTTTTGGAGAATCTTCCTCTGTCACCCAGGCTAGATGGAATGCAGTGCGCGATCT +CGGCTCACTGCAACCTCTGCCTCCTGGGTTAAAGCAATTCTCGTGCCTCAGTCTCCCAAG +TAGCTGAGACTACAGGCGCCCACCACCACACCTGGCTAATTTTTTTTTTGTCTTTTAGTA +GAGACAGGATTTCATCATGTTGGCCAGGCTGGTCTCGAACTCCTGAGCTCAAGTGATCTG +CCTGCCTTGGCCTCCCAAAGTGCTGGGATTTGTGCTGGGATTACAGACATGAGCCTCTGC +GTGCAGCCTACTCAGTTCAAATTATTTGTTACCTTTCAGGTCACAGCTTTTATTTTAGTT +TTATTGTATTGGGGCGAGAACACTTAAGGTGAGATCTACCCTCTTAACCGGTTTTTACGT +GTACAATACATTACTATTGACATAGAAACTGTGCTGTGTAGCAGATCTCTAGAGCTTATT +CATAACTGAAACTGTCCATTGGTTAGTAATTCTTCATTCCCCTACCCCCACCCCCTGCAA +CCACCATTCTACTCTCTGATTCTATGAATCTATTTTAGATACTTTCTTTATATGTGGACT +CATGCAATATTTGTCTTCCTGCAACTGGCTTATTTCACATAGTTTAATGCTTTCGAGGGT +CATCCATGTTGTTACATATGGCAGAATTTCCTTCTTTTTTAAGGCTGAATAATATTCCAT +TGTGCATGTGTATAATGTTTTCTTTTCTTTTCTTTCTTTTTTTTTTTTTGAGACAGGATC +TCACTCTGTTATCCCGGCTGGAGTGCAGTGGCATAATCACACTAGCGGCATCAACCTTGA +CCTCCTGGGCTCAAATATTGTCCCAACTCAGCCTCTTTGAATAGTTGGGACCACATGGGC +AAGCCACCAGGCCCATCTAATTTTTGAGTTTTGTGGCGACAAGGTCTCACTATTTTTCCC +AGGCTGGTCTTGAACGCCAAGGCTCAAGTGCTCCTCCAGCCTTGACTTCCCAAAGTGCTG +GTGTTACAGGTGTGAGTCACTGCACCCAGTCTTTTTTTTTTTTTTTTGAGTCTTGCTCTG +TTGCCCATTCTGGAGTGCAGTAGTACAATCATAGCTCACTGCAGCGTGAGCCACTGCACC +CAGCTACCTCATTTTTTGTTAGCAATTTATCTGTCAATGGACATATAGATTGTTTCCACA +TCTGAGCTCTTGTGAATAATGCTGCAATGAGCATGGGAGTGTAGGTATCTCCTCAAGATC +CTGATTTCAATTTGTTTGGATATGTACCCAGAAGTAGCATTGCTGGGTCATGTGGTAGCT +CTATTTTTAATTTTTTTAGGAAACTCCATACTGTTTTTGTTTTGTTTTGTTTTGTTTTTG +AGACAGGTCACCCAGGCTGGAGTGCAGTATTGCAGTCTCGGCTCACTGTAACCTCTGCCT +CTCCAGTTCAAGTGATTTTCCTGCCTCAGCCTCCCGAGTAGCTGGAATTACAGGCGTGTG +CCACCATGCCCAGCTAATTTTTGTTTTTTTAGTAGAGACAATGTTTCACCATGTTGGCCA +GGCTGGTCTCAAACTCCTGACCTCAGGTGCTCAGCCCCCCTCCGCCTCCCAAAGTGCTGA +GATTACAGGCATGAGCCACTGCACCCGGTCCCCATACTGTTTTTCATGGGGACTGCACTG +TTTTGCTTTCCTACCCACAGTATGAAAGATTTTCTTAAAGGATGGGTTTGAAAGTTTGAT +TCATTTTATTTGTTTAGAAAAGATAGGAACTACCAGGCACGGCTGCTCATACCTGTAATC +CCAGCACTTTAGGAGGCCATGGTGGGTGGATCACCTGAAGTCAGGAGTTCGAGACCAGCC +TGGCAAATGTAGCAAAACCCCATTTCTACTAAAAATACAAAAGTCAGCTGTGCATGGTGG +CATGCGCCCATAACCCCAGCTGCTCAGGAGGCTGAGGCAGGAGAATCATTTGAACCCAGG +AGATGGAGGTTGTAGTGAGCCAAGATTATGCCATTGCACTCCAGCCTGGGTGACAAGAGC +AAAACTCCGACTCAAAAAACACACACACAAAAAGAAAGGATAGAAACCATTTGATACCAG +ATCAAGTCCCTGGTCCAATTTATTGATTCTTACAAATGTGGGAGTAAACAGTCCCCAGGG +TGGCCCTCTCTCCCCTGCAGACAGAGAACTTTTTGGAGCATGTTGAAATGTTCTGCTTTA +GCATCAGTAGTCGTCAGCCTAGTCAGGGACTAGTTTGTGGAATAATCTTCCCTATATAAT +CAAACTGGCTCATTTCATGTAACAATGTGGTAAGACAAAGTAGACTTGACTGAACAAGTT +CAGTGTCACAGTTTTGAGGCCTAGTTTTGATACAGTTGCAATTTGCAAGAAATGGAAATG +CTACTACCATCAGTTTTGTAGCACTAACGATCTCGGATCCAGCAGGGAGATGTCTTTTCT +CCTACTTATCCTGGAGAAAAAGGTCCAGCCATAAACACAGCAAGTTGTCCAGGTCTATGT +TTCATCATTCCGTCTATTCCACAAACATTTGTCGATCCAGGAATTAAGGAGTGAGCAAGA +GAAGCATACCCCAACTCAGGAGGACAGACTTCATGTTAAACAAATAAGTACACATTTAAC +TACAATTGCACAAAGCGCCATAAAGAACTACAGAAGCCAACTACAGTTGGCACTGGTCCA +CCAAGAGGCTGATGACTACTGATTAGTGCTGGAAAACTGATGGTATTAGTAATAACACTT +CCAGCTTCTCAGGAGGCTGAGGCGGAAGGATTGCTTGAGGCCAGGAGTTCGAGACCAGCC +TGGGCAACATAGCAAGACCTCATCTCAAAAGAAAAAGTTTTCTTTTTTTCTTTTTTTTTT +TTTTGAGATGGAGTCATGCTCTGTCACCCAGGCTAGAATGCAGCGGTGTGATCTCGGTTC +ACTGTAACCTCCGCCTGCTAGGTTCAAGCGATTCTCTTGCCTCCGCCTCCCGAGCAGCTG +GGATTATAGGCACCTGCCACCGTGCCTGGCTAATTTTATTTATTTATTTATTTATTTGTA +TTTTTAGTAGAGATGGGGTTTCACCATCTTGGCCAGGCTGATCTTGAACTCCTGACCTCG +TGATCCACCTGCCTCGGCCTCCCAGAGTGCTGGAATTACAGGCGTGAGCCATGCGTCCAG +CAAGAAAAAGTTTTTTAATGAACCATAGAGACCTCTCAGAGCTCCAGATTTGGGGGATGG +GGTCAGATAATCAGGAGAGTTCCCGAAGAAAGTGCCATTTGAGCTGTGATCTGAAGGAAC +ACTAGTAAGTAGTCAGCTAGGCACAGATGGGGAGAGGAGAGGGCATTCTGGGCCGAGGAC +ACAGCGTGGGTGAAATCCTGGAGGTGGGAAGCGGCACTGTGCTCCAGAGGGACTGGAGGA +GAGCCAGAGTGACTGGCACATCAGGAGGGCACAGGGGATGCCCGAGCTGCTGGTGAGACA +GACAGGACTGAGAGAAACAGCAAGCTGGTCTCTGACAGCTTCCCGTCAAGTGGTGATCTG +TCTCCCTTCGTCCTCCCCTGCCCTCCCACTATCTCTGTTTTCCCCAGTGCCCTTTCTTTC +CTTTCCCTGTTCTTCCTTTTGGAAGAACATACGAGCTCACCTGTGTTCTGGTTCCTTTTC +TAAAGGGCTTTATGATTACTTAACCAACCTCATAACCATGGACCAGCCAACATTTCACAA +ATACTCACTCAAAACAAGCCTGTTATTATCACCCTCGTTTCACAGAAGTGGAAACTGGGG +TGCAGAAAGATGAAGGGTCAGCAGCTGGTCAGTGACGAGCCAGGGTCCAAGGCCAGGATG +TCTGCCCAGCCGCCATGCTCACTGCCTTTCATCTTGGTTCTCCTAGGAAGAGTTAGTTAC +TTCTAGGGTATTATTAGATTGGTGCAAAAGTAATTGTGGGTTTTGCCATTGAAAATAATT +ACTTCTACACCAACCTAATACTTTTTTCCCAAGGGGTTTAGTAGAAGGATTCCTGCAGAC +CAGAAACCCAGAGGGATATTGCTGATGTGGTAGGTGTTGGGCCAGCAGGGAGAGAGGTCT +GAGCCCCTGCCAGGTGCTACCTGGGAGCCACTTTGTCAGCATTTGTTTGTTCTACTTGGG +AGGTAGCCCTGCCAGGGACACCTGGGGACACCTTTTCCCACTGGAAGCGCCATCTGAATC +CAGAACCGTTTTCTTTGTCTTAAGAAAAAAAAAAAATCTTTGTCTGCCTTACTTCAGCTG +TTGGCACTGAACCATCTGTACATTTTTTTTTTTTTTTGAGAGGAGTCTCGCTCTGTTGCC +CAGGCTGGAGCGCAGTGGCACGATCTCGGCTCACTGCAACCTCTGCCTCCCAGGTTCAAG +CAGTTCTCCTGCCTCAGCCTCCCAAGTATCTGGGACTACAGGCACGTGCCACCATGCCCA +GCTAATTTTTGTATTTTTAGTATAGATGGGGTTTCACCATGTTGGCCAGGCTGGTTTCAA +ACTCCTGACCTCAAGCAGTCCACCTGCCTCGGCCTCCCAAGGTGCTGAGATTACAGGCTT +GAGCCACCACACCCAGCCCATCAGTACAATTAAAAAAAAAAAAGTTACAACCACTGAAGC +ATGGATGTCACATGGGAAACTTTGTCCATGTACAGAAGGTTGGAAATAGTCTCCCAGCTC +TTCGGTTGTGAGCAAAAGCTCACGGAAATGGCTCACTACAAACCTTTACGTCTCCACTGG +CCCTTGTACCACCTTTTTGACAGTGTGTTGCATGGTCTGTCACAAGACTTATGCATTTGT +GTTGAAATGAAGTTGCTGGAACATTCAGATTGTTGTCTATTCCCAAGGCAGATCCTTAAA +TAAAATATATTTTTGGACAGCCACATAGCAGAACCGAATAGCCTAGTTAAAAACAGCTGT +TAGCAAAAGAAGGCTGGGGGGGCGGGGGTGGGGAGGCGGGGGGGCGGGGAGGTTCCCAGC +TGAAACCAGCTCTGAGTGGAAAGCAGATCATGGCATGGGCAATTTTGATGTGTGTAGTTT +GTGGATGTCAGACTTTTGAGCATCTTGTATTCTCATTCTTGCCAGTATCATAAGAGCAAT +TCTTTTTTTCTTTTTGTAAGATGGTCTCACTCTGTCACCCAGGCTGGAGTGCAGTGGTGC +CATCATAGCTTTCTGTAGCTGAGACCACAGGTGCACACCACCACACGTGGCTAATTTTTT +TTTTTTTTTGTAGAAACAATATTTGTTATGTTGCCCAGGTTAAGAACAATTATTTATTTA +TTTATTTATTTATTTATTTATTTATTTATTTATTTATTTTTTTGGAGACAGAGTCTCGCA +CTGTCACCCGGGCTGCAGTGCAGTAGTGTGATCTCTGCTCGCTCATCCTCCACCTCCTGG +GTTCAAGCAATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGCGCACACCACC +ACACCCGGCTAATTTTTGCATTTTTAGTAGAAACGGGGTTTCGCCATGTTGGCCAGGCTG +GTCTCAAACTCCTGACCTCAAGGGATCCGCCCATCTCGGCCTTCTGAAGTGCTGGGATTA +CAGGCGTGAGCCACCGCTATCTAGCCCAGGCTAAGAGCAATTCTTACAGATATTAACAGC +TTGTACAAAACATCCCACGCCCCTCCACAATTGTCCTCACCCACTTGAAAGTATGACTGC +AATATGTACACACATTCACGTTGGATATAATGGCAATGCTGCTCATACTCCACACTTGTA +TTCTAAGTAGCTGACTGCATGTATGCCTCCCCCTGTTCACAAGTTCTATAAAGTCAGAGA +CGCTTGGTTTATCTGCAGAGAGGCAGTGCGAATCTGGTACCAGTAGTTAGAAATGTCCAC +TCTGGAGCCAAACTCCTGGGGCTTGAACCTTGGGTCCCCCATGTACCAACTGTGTGACCT +TGGGCCACTTACCCTCTCAGTGGCTCATTTCCCATCTGCGAAATGGGGCTTCGTCGTAGT +ATCACCCTGGAACATAGAAAAGCTATGGTAGCTGCTATTAATATTAGCTGTTGTTGTTTT +CATAGCCACTTCAGTACCTGACACATAGAAGGTACCCAAAAACTACAATCCATTCAACAT +TATTCACCCAATGCATGTCAGTGCCCAGCACTGTCCCAGGAGCCAGAGACAGGGCGGGAT +TGAATGTCATCAGGGACACCATCCACATTGAGTTCCTGGAGGCGCCATTAACAGAATACA +GTGTGCAGCCAGCAGACCTGGCGGTGTATTGGCAAATGCAATAGATGAAGTGCCTGTCCT +CCTGGAGGTTATAGGCTAGCATGAAACAGAGAGAACCAGGAAAACCACGAGATATTGTTG +GGCAGGTCATTGAAGGAATACCTAAGATCATTTCAGATAGTGAGAAGTGCTCTGTAAAAA +ACAACACAGAGGCTGGGCGCGGTGGCTCATGCCTTTAATCCCAGCAGTTCAGGAGGCCAA +GGCAGGTGGATCGCTTGAGCCCAGGACCTTGAGACCAGCCTGGGCAACATGGCAAGACCT +CATCTCTACAAAAAATAGAAATTCGCCAAGCGTGGTGGTATGTACCTGTAGTCCCAGCAC +CTCAGGAGGCTGAGGTGGAAGATCGCTTGAGCTCAGAGTCAAGGCTCCAGCGAGCTGTGA +TTGTGCCACTGTACTGTAGCCAGAGTGACAGAGTGAGACCCTGTCTCAGAACCCGCCCCC +CCCCTAAAAAAACAGGATGATTTGTGATGAAGAGAGAGTAAGAGGACTGCAGATGGAATG +TCAGGGAAGGCCTCATTAAAGAGCTAATGTGTAAGATGAGAACTGCAGGCTACCAAGGAG +CCGTCTGGCCAAGCCCTGGGGCACAGACTCTAGTCAGAGAGAACGTGCCTGGCTGGAGGC +CAGCACCTGGACGTGTGTGCCAGCCCCTGGTGCCACTCTGTGCCCTTTGTCCTACTGTGT +GTGGGGGAGACTGGCCTCTGGGGACTGCCTCACCTATCCTTCCTCTAGCTCCCAATTTGT +TCAGCCAGTAGGAGGCAGCAGCATATGCAGGGCAGGAGGAAAGCGAGGCTGGGGTATTTC +TCCCCCATTCCTCCTGGGCCATGTTTTGGCGATGGCTTTGTTCCTGCAAGCAAGACTACA +TCTTGGGCTAGATGGCCTCTTGCCGCTGCAGGTTCCAATCATGCTGTTCCCCCTGCCGCT +GCGGGTTCCAATCGTGCTGTTCTCCCCACCTTAATGTGGCTGGGGTAAGGGAAGGGGACC +CGCATGGGGTGGGCTAGCAAGGCCATGGAAGGGGCTGGCCGTGCAGAGCTTCTGCACAGA +GTGAGAAGTCTGGAGAGCTTTCAGCAGGGCATCCCCAGACTCACATACACCTTTTTGGAA +TGGAATTGAAGCTGCTTACTTTTTTACACCCCAAAACTTTTTATAGATTCAGTTTAGCAT +CTGAGAAACACTGTTTGCTATAAACTCTGTGACTGTCTCTCAGGTTTTGCCTCTCCCAAG +AGAGCGTCCTCCATTTGGCTGTTACCGTTGTTGAGCATCCCAAAGAGTGAGGCTCTATTT +AAAGTCACTGCCTCGAGTGGTGGCAGGGATCATCCGGGGGCTCACCCAGCGTAGGTGGCT +TCTACCGTTCCATCTGCTACGATACCCGCGATCCTGCTTTTGTGGTTGGAACAGGGCTTC +CTTTTTTTTTAACTCCCACCACCCACAGAAAAATAAGAGTGTAATTTTGGAAACAGGCCA +TTAAGCTGACAGGTAACTTTGCCTTCTCCTTTTTGGGATCCAAAAAGGGATTCTCAAAGC +TCGTTTGCCCAGACAGGAGCGTGTTGATTCGTGGGAATCACGTTTTGTCATTTTCCTCTG +TATTGTTTAACCAGGCTTGTGAGTGGGTCTTGCCTTTGTTCAGTAACTGACAACGTTAAT +TTCTCTACAGCTGCTGCGGGAGGATCTGGGCTTCTGTGTTGATTTTCTTTTTCCCTCCCT +GCTTCATCTTTGGGATTATTTATCCTTTTTTCGGTTCTCTGCTAGGATCATCCTGAACAT +GGGGTCCTGTTTCTTGTTCGAGAGCTTCTCAACGTGATCCAGGACTACACCTGGGAGGAC +AACAGCGATGAGAAAATCCGCATCTACACCTGCGTCCTGCATCTCCTCTCCGCCATGAGC +CAGGAGACGTACCTTTACCACATAGACAAAGGTAGCAGAGCCTCCCCCACCAAACCATGC +TCCGCATGGATTTCATGAAAGGCAGACAGAATGCTTTCATTTTCTCTTTTATTTTTTCCT +CCCTTGTATTTTAGCTTCCATGAACTTCTAGTCCAGGGTCTCACTGTATTTACCTGATCT +AAGATTTACCTGGAGCAACTCTTAAGAGTACAGATTCTTGGGCCGGGTGCAGTGGCCCAC +GCCTGTAATCCCAGCACTTTGGGAGGCCAAGGCAGGCGGATCACCTGAGGTCAAGAGTTC +CAGACCAGCCTGGCCAACAGAGCCAAACCCTGTCTCTACTAAAAAAACAAAAATTAGCCA +GGCCTGATGGTGCACCCCTGTAATCCCAACTACTCGGGAGACTGAGGCAGGAGAATCGCT +TGAACCTGGGAGGCAGAGGTTACAGTAAGCCAAGATGGCACCACTGTACTCCAGCCTGGG +CAACAAGAGTGAAAACACCATCCCAAAAAGGAAAAAAAAGAGTACAGATTCTTCAGCCCC +ATCCTGCCCTTGATTGATTGATTGATTGATTGATTGATTGATTGAGACAAGGTCTCACTC +TGTCCCCCAGGCTGGAGTGCAGTGATGTGATCTCGGCCCACTGCAGCCTTTACAGCCCAG +GCTGAAGCAGTCCTCCCACCTCAGCTTCCCAAGTAGCTGGGAATACAGGCATGTGCCACT +GCTCCTGGATAATTTTTTAAATTTTTTTTTGAAGACGGGGTTTCACCATGTTACGCTGGT +CTCAAACGCCTGGGCTCAAGTAATCTACCCGTCTCAGCCTCCCAAAGTGTTGGGATTATA +ACCATGAGCCACCACACCTGGCCTTCCCTTCTTAATTTGCATCTTTAACAAGCACCTGAG +ATCATGTTGAACATCAGACCAGTCTGGAGAAACACTGTTTAAAAAAATAATTATAATAAT +TTCAACTTCTATTTTAGATTTAGGAGGTATACGTGCAGGTTTGTGACAGGGGTATATTGT +GCAATGCTGAGGTTTGGGGTGCAAATGAGATAGTACCCAATAGGTAGTTTTTCAGCCCTT +GTCCCCTCCCCTTCCTCCCCACTCTAGTGGTCTCCAATGTCTGTTGTTTCCATCTTTATG +CCCATGGGTACCCAATGCTTGGGGCCCACTTACAAGTGAGAACATGGCGGTAGTTAGTTT +TCTGTTTCTGCACTAGTTCACTTAGGATAATGGCCTCCAGTTGCACCCATGTTGCCACAA +AGGCCATGATTTCATTCTTTTTTAGGGCTGCATAGTATTCCATTGTGTGTATGTACCACA +TTTTCTTTATCCAATCCACTGTTGATGAGCATCTAAGTTGATGCTATGTTTTTGCTATTG +CGAATAGTGCTGCAGTGAACATACGTGTGCATGTGTCCTTTCAGTAGAACGATTTATTTT +CCTTTGGGTATATACCCAGTAATGGGATTGCTGGGTCAAATGGTAGTTCTGTTTTCAATT +CTTTGAGAAATCTCCAAAACTGCTTTCCACAGTGGCTGAACTAATTTGCATTTCCACTGA +CAGAGTGTTAAGTGTTCTCTTTTCAGAGGAACCCTCTTTTGGATCAGTGTGCTACACAAT +AAACTGGAACAATGGCTAAATATACACATGCATGAGCTTCGTGCCAGGCCTGTTCCTTAC +CACAGTCTCAGGAAGGACCCTGGTGTGGGTGTTTGCAACTGCTCCTCAGATGATGCCAAG +GCTCAGCAGCCCTTGTCTGGGTGCTCTGGAGGAAGGAGGTGGCCTTGATCACCTGCTACC +AGACATTTTGAACTTGCTAGTACAAGTTGGGAGCAGCCTCCTCGTGTCCTGGACTTACCA +CAGGACATCCCAGTTCCAGGCCTTTTCCCACTGAGCCCAAGTATCCTCCTGCCTGGCGGA +CCCTCAGTTCTAATTTTTGGATTCCAAAAATTGGTCTTAATGTCAAAAGTGCTTTGGCCA +GTAATTGTATACTTTACAGTTAAAAAACCAACTCTACACTTGCAAGTTGCAGTGAACACA +TTAGCAGTGCTTAAGGGATGGCCTGCCTTCTGTCATACCTCTCAGGCTTTCTCTAGCTGG +GTCTGGGGACTGAGGATAAAGATGTAATGCAGGGAGGCTGGTTCATAGCAAGAATGATGG +CGCCTACCCTGATCTGAGCACTTACTGCGTGCCAAGGACTACATCAGGCTCTACAGGCCT +TTTTCCCTTAATCCTTACAGCTTTACTATGAGGACAGGCATTCATGTCCCCATTTGATGT +GTAAGCAAGAGGAGATCCAGAAAGACAATGTGATATACTCCAGGGCTTCCGGTAGTTAGT +GATGGAAGTGAAACTCACACCCAGAGTGGTGGGACGTGCATTACACTGCTTTGTTGATTA +CAAAATAACAGTGTTGGCTGGGCACAGTGGCTTGTGCCTATAATCCCAGCACTTTGGGGG +GCAGACGCAGGCGGATCACCTGAGGTCAGGAGTTCGAGGCTAGCCTGACCAACATGGCGA +AACCTCATGTATACTAAAAATACAAAAAAATTAGCCAGGCTGTTGGCAAGCGCCTATAAT +CCCAGCTACTTGGATGGCTGATGCAGGCGAATCGCTTGAGCTCAGGAGGCTGCAGTGAGC +CAAGATCACACCACTGAACTCCAGCCTGGGTGACAGAGCAAGACTCCATCTCAAAAAAAA +AAAAAAAGCAATGTTTTAATTAAAGTGTATTATATAACATATATGCAATAAACTATAGAG +CTCAGTGAATTGTCACAAAGTGAACACTCGCAGGTAACCACAGTCCAGATCAAGAAATAG +AACACCTCCTTCAGTCAGCATCACCACCCTACTCTCGAAGACACACCACTCTCTCTCCTG +ACTTCTAGCATTATTTATTAGTTTGCCACTTTCTGAATAAGTAAATATTTGCAAGCATTC +TTTGGTATTTGGCTGCTTTAACTCAGCATGATGTCCAAGATTCATCTGTGTTGGTATGCA +AAACGGTAGTTCACCTTTTGCATTGCTGTATAGTATTCCTTTGTGTGGATGTACCAAAAT +TGATTCATTCCTTCTGGATGGAAATTTGCATGTGGCCAGGTCCAGTTTGGGGCTATTATG +AGTAATGCAGCTGTGAACATTCTTGCATGTATTTCTTGGTGTACATTCCCATTGGCTGTC +TGCGTGGAGGTGGCGTTGCTGGCTCATAGGATCTGCTTATATTCTGCGTTGGAGGATACT +GCCTCACAGTTTCCCAAAGGGTTAAACCAATTGACATTCCCACCAGGCACGAATGAGGCT +TCCATTTGTTCAGTTGCTATGGTCATTCTTTTTCATGTCAGCTGTTCTAGGAGTGGAGTT +TGCATTTCTCTGATGGCTGGCGAGGTTGAACACCCTTTCCTGTATTTCTTGGCGTCTTTG +TTTCCCCTTTTGTGAAGTGAACATTGAAGGCTCTGAACAAGAGAGAAAGCTTTGAGGACC +AGACAGAGACCTGGAAGTGAGGCTATCACAGGAGCATGCCCTGCCCTCTCCTCTCTCTCC +TCTCCTTCCTCTCCCTCCTCTCCTTCCTCTCCCTTAAACAGATTCAGCCCATCCTTTCTC +TGAACAAGGCCGCCAGCGAAGACGACTAGAGCCAGATTGGCAGCAGAGGGAGCGAGGCTA +TATTTGATAGGCAAGAGTGTAGTTTTCTAGCTTTTAGAGATGAAAACAGAAGGATGGATT +TTCTTTTTCTTCTTCTTAGTCCAGCTGTGTTTACTTTGAATGTGCAACTGTGACCTGCCC +GGCGTCTTGGTAGGAGACCCAGGGAATCACAGAGTCTCTGCAGGTTGTGGGGGCTCCTTT +TTCCCTGTTCACTTCCTCATTCTAGGGAGGCTTTTAGACGATGTTGACACAGCTTAGAAC +TTGGAAGAGAGGGATTAAATAATTTCTGCATTTTTGGAGGATGCCTTGGCCACTTTCTTC +CCAGATTAAGAAAAAGAGAAGGCTCTGACATTGCCTGGAGCAATCCCTCCGGTGCTTTTA +CACGAGGTTACAAGACAGCGTGCATGTTTGATGTAGAAGTGAAGAATAGTCTTGGATCCT +CAATGTTTATGTATTTAGTATGCAGATAGAGTGTGTCTTTATTGGAAGAGTACAACTCAG +GATGCTTCTGTGAAGCCAAGGCAGCCCTCCTCACTCTTCCACGTCACCTGCCAGGCCCTC +AAAGCATTCGGGTTTGCAACTTGGGGTGGGACAGATGCAGAGATTGTGGGCTATTTTTAG +TGGCCATTTGCAGGGGACATCATTTCTCCCCCTCGTGAGAGCCACGTCTGGACTTGAAGG +CCCCCAATACACTCTGACCTGACCAAATTACTTTTAATTCTCAAATGCGCCCTTTTCTCC +TTCCCTCTATGACCACCAAGTGTCAGCATGGAAAATAAATTCCTCCCTTCTCACCCCTTT +TCCCACTTCTGCTAGCGAATTCCACCTTTAGGACTCAGTCCAGGTCTCACTGATTCCAGA +ATCCTGTCCCAAGCATAGATTTTAGTATCCCATGATCCCCTGTACTGCCCCCCCTTCCTT +GAGACTGGGAGGCGGAGGTTGCAGTGAGCCAAGATCGTGCCACTGAACTCCAGCCTGGGC +GACAGAGCAAGACTCCATCTCAAATACCTCTGCACACTATTGCAATTGCCTGTTTGTGTG +TCTGTGTCTCCTCACAGACTGTGACCTCTGTGTCTGTGAGGGTAGGGCCAGGTCAGCCTT +GTCCCCCACTAGGTTCCCGCTCCTAGCCTAGAAGCTGGCATGAAGCAGGCCTTATTCAGT +AGGTGTTGCATGTGTGTGTGAGTGGCCTGCTCTAAACACACCTCTGGCCCCTTGGGGTGG +TTGGACCTTCCCTCTTCTCCATTGCTGGGCTGTTCAGAATCAAAGTGAACTCCAACCTGG +AGGAAGACTGGGAATTTATGCAGGAACTATTCTGGTCCTCAGCAGCAGACATGAGAAATT +CCTTCACCAGCTGCAGTTTTGCTGCCCTGCACAATCAGGTGGTGTTGAATGGCTGAATTG +AATTCTTCTCGCTTCTTACAAGAGTAACTGCCGTCCCCCACTGGGGAGGTACAAGTCATG +ACACAGCAGCCAGAGCCGGCTTGGAAATTCTGAGATTGACTCCTGCGGCCCAGGGCCAGT +AACTACCAACCTGGTGTCAGACGAGCAATCAATCGCAAAGGAAACCTTGGGGAAGTATCC +CAGCAGAGTCCCCATAAACGAGCAGTTTAAGATTGGATAAGAGATTCCTGTGATCAGAGA +AGCTGGGGAACAAAGGAAACCAGTTGTTCTCCTTATTCTTAGGCAATATGCCTGCAACCT +GCTTTCAAATGGTTCAGCCAAAAAAAAAAAATTATGTGTGTCTGTCCATCCTTGTAGAGA +CAACAAGCAAGAGAGCTTGCACAAAAGTAGCAAAATATTATCAATTGGTGATTCAAGAAG +TAGGTGTTCATGGCCGGGCGCGGTGGCTCATGCCTGTAATTCCAGCACTTTGGGAGGCCA +AGGCGGGAGGATCACTTGAGGTCAGGAGTTTGAGACCAGCCTGGCCAACATGGAGAAACC +TCATCTCTACAAAAATACAAAATGTAGCCCTGCCTGCAGTGCAGTGGCGTGATCTCTGCT +TGCTGCAACATCTGCCTCCTGGGCTCAAGTCATCCTCCCACCTCAGCCTCCCGAGTAGCT +GGGATTACAGGCACACATCACCACATAGAGCTAATTTTTGTATTTTTATTAGAGACAGGG +TTTCACCATGTTGCCTAGGCTGGTCTCAAACTCCTGAGCTCAAGTGACCTACCTGCCTTG +GCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACTGTGCCTGGCCATCTCGTGCTGTT +TGTCCCTCGTTTGTGCACAGGCCCTACTGTGTTTCTCATAAATATTGTCTCTTTTGAATT +GTGTGTATCTGAGACAGTATCCTTCCTACTTGTTTCCTCAAGACAGTGATGAATGTTCTT +TCAATGGGGCGAGAAAAGCACAACAAATCACATTCTAGCAGATAAGCTAAACTGGATGTG +GTTTATTAAAGACATCCCTAAGCCACAAAACTGGATTAGCCGTGTGCACTTGTGGCCGCG +TGTACACAACCACACCCCGAGGCACAGGCATGGCTCTTGGTTTATGAGATATCCACGCAC +TCAGGACAGTGACCCAGATTGCAGGCCCGTGCCAGGTGAGAAGCAGCGAGTGCCGCCGCC +GCACCGTCCCCCTTCCTGACCACTGAGTGCTGTGTTGGCTCCAGAGCTCTCCCTTTAGCC +TGGGGGTTCAGATGCTGAACTGGGCTCCCCAGACAGAGTGCTGCTTGTTCACAGCCGGTT +ATGCTCGGCCACATACAAGTCCCCATCTGGTAGCTGGAATGAAAGCAGCTGTAAGAGGAT +CCCATGGAAAAGGTATGTGAGCTCATGTGGGTGTGGAAGGAAAGAACTGGCTCTGTAGGC +AGAGCTGGTGGTTTTGTTGTGAACTCTAGGGTTTGCAGCAGGCTGGCCCTAGCCAAAAAA +GGAAGGAAGAAAACCACTGAAGTGTTCCCAGTAGGGACCAACTAAATACATTCTCTTCCA +TCGTACAGTGGGATACTACGCAGACATGACAACAAAGCAACAGAGCTGTACGCGTAGCGC +CCCCTTACCCGGTGTCTCTTCTTTTTTTTTTTTTTTTTGAGATGGAGTCCCACTCTGTCG +CCAGGCTGGAGTGCAGGAGCGTGCCAGTAGCTGGGACTACAGGCGCGTGCCACCACGCCC +AGCTAATTTTTGTATTTTTAGTAGAGACGGGGTTTCACCATGTTGACCAGGATGGTCTTG +ATCTCTTGACCTCATGATCCACCCGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGTGTG +AGCCACTGTGCCTGGCGTTTTTTTTTTTTGAGACAGAGTCTCGCTCAGTCACCCAGGCTG +GAGTGCAGTGGCTCCATCTCGGCTCACTGCAACTTCTGCCTCCTGCGTTCAAGCGATTCT +CCTGCCTTAGCCTCCCAAGTAGCCGGGACTACAAGCGTGCACCACCATGCCCAGCTGATT +TTTTGTATTTTTGGTAGAAACTGGGTTTCATCATGTTGGCCAGGCTGGTCTCAAACTCCT +GACCTCAAGTGATCCACCCACCTCAGCCTCTCACAATGCTCAGATTCTAGGTGTTAGCCA +CAGTGCCCAGCCCCAGTTTCATTTTCTGCAGTTTCAGTTACCCCACAGTCAACCTGGTCC +AAAAATATTAAGTGGAAAATCTCAGAAATAATTCATAAGTTTTAATTTGCACACTGTACT +GAATAGGGTGATAAAATTTCACTTCGTCCCACCCAGGATATCCATCATCCCTTTGTCCAG +TTTATCCACACTGATGCGACACTACCTACCCATTACTATATAGGAAAAAGCATAATATAT +ATAGGATTCAATACTGTCTGTGGTTTCAGGCACCCACTGAGGGTCTTGGAACGTATCCCC +CAAGGATAAGGGGGCATTATTGTATGCTGATATAAAAATAGCACGAAGATTTATTTTATT +TTGTTTATTTTGAGACAGGATCTTGCTGTGTTGCTCATACTAGAGTGCAGTCATGTGATC +ATAGCTCATTGCAGCCACCTACTCCTGGGCTCAAGCAGTCCTCCCACCTTAGCCTCCCAA +GTATCTGGGACTACAGGCGTGAGCTACCAAACACAGCTAATTTTATTTGGAGAGATGGGG +TTTTGCTATGTTGCTCAGGCTGGTCTCAAACTCCTGGACTCAAGTGATCCTCCTGCCTCA +GCCTCCCAGAGTGCTGGGATTATAGGTGTGAGCCACTGATCCCAGCCCCAAGATTTATCA +TTAAGTTAAAAAAACAAAGTGTAAAGCAGCACAGAGTGTGGTGTCTCTTTCGTTGCCCAG +ATTATGCTCTGTGTGAAGTTCAGTTGAGAGGAAGGAGTGGGGAGGGAAGGAGGGAGGGAG +GAGGAAGGGAGGAGGAACTCAGACTCAGGCTGTCCTTGGCTGGGCCTGTCTTACTCTAGG +CAGTGGTTGTCACAGGACGAGACCCAGCAAACAGTGGAGGAGCTTTTGGCAAGAGACATT +ATCAAAGGGATTTACACTTCTAGAGTAGTTGAAATAGAAAATCTCTGCAGTCCTTCCAAA +GCCAGGTTTGAGGAGAGGGTGACAGGGCAGGCAGCTGGATGCGGTAGCTAAGAGCGTGAG +CTCTGGAATCAGACTTCCTGGTTTAGGATCCCAGCTAGGACCACCTCTGAGCCTCATCTC +CCTAAAAGGGAGATATTAATATCATCTCTTGGCTGGGCTGGTGGCTCACACCTGTAATCC +CAGCACTTTGGGAGGCCGAGGCAGGCGGATCACTTGAGGTCAGGAGTTCGAGACCAGCTT +GGCCAGCATGGTGAAACCCCATCTCTATTAAAAATAAAAGAATAAATTAAAAAAATAGCC +AGGCGTGCTGGCAGGTGCCTATAATTCCAGCTACTCAAGAGGCTGAGGCAGGAGGACTGC +TTGAGCCTTGAGGCGGAGGTTGCAGTCAGCCAAGATCGTGCCACTGCACTCCAGCCTGGG +TGACAGAGAGAGACTCCGTCTCAAAAAAAAAAAAAGAAAAGAAAAGAAAAATCATGTCTT +CACATACTGGTTGTGGGGGACTCTGCAATAAGGCAGTGAAAGCCCTAGCCCAGTGCCTGG +CAGCTGCTGTGATGATGATTATTATTATTAATGTCACCCCCGCTCCCCGCCACGCACACA +TGGGCTAGAGGGGTGACTTCCACACCCCTGGCTTAGACTGTCCTGCAGGCTGGGTGTTTT +CTTTGTGATTCCCAAGGCCCCAAGCCCAGTGGGAAATTTCCGCCACTTCCATGTGCCCTG +CCACGACTTCCTGCCATCTGCTGACTCGGTGTGACATGACACACGGCTGCCTCTCCCTGG +CCAGCATGGCCGCGGGGCTTGGGTCTGTCTCACTGTTCTTGTTTGTTCAACAGTGGACTC +CAACGACAGCCTCTACGGGGGAGACTCCAAGTTCCTGGCAGAAAACAACAAGCTGTGTGA +GACGGTGATGGCTCAGATCCTAGAGCATCTGAAAACCCTGGCCAAGGACGAGGTGGGTGC +CCTCTGCTGTCCTCCACCCGCCCCTTGCTCTGAAAGCACAAGTTTCCAGGGTGGTTCAAC +CTTGGTTCATTCTAGAAAGGAAACTATGTCATGTGAGTAATGTGTTTATGTGCAAACCAC +TTCTCCATTGCTTTGGGGCCTTCGCTCCTGCTGTTTTCTCTGCCTGGACTGCGCCTCCCC +CAGGGCTTCCCCTGGCTGTTCCTTCTCGTCATTGAAATCTCAGCTCAAAGGACCTCCTCA +GGCCTTCCCGGACCCTGTCTGAAGGAGCCACCACCACCTGCATGCCTCTGCCCGATTGTC +CCTGTAGCGCCTGTTCAGTCACCGTCTGAAATGTTCTGTCTGTCCATCCCTCAGCTCCCT +GACTAGAATGTAAGCTCCATGGGAGCAGGGACCTGGTGAGTCTTTTTTTTTTTTTGAGAC +AGTCTCACACTATTGCCTGGGCTGGAGTGCAGTGGCATAATCTCGGCTCACTGCAACCTC +CGCCTCCCGGGTTCAGGCGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGT +GCCCGCCACCACACCTGGCTTATTTTTTGTATTTTTTTAGTAGAGATGGGGTTTCACTAT +GTTGGCCAGGCTGGTCTTGAACTCCTGACCCTGTGATCCGCCTACCTCGGCCTCCCAAAG +TGCTGGGATTATAGGCGTGAGCCACTGCACCCGGCCTGGACCTGGTGAGTCTTGAAGACC +TGCCTGTGTCTGAATGACAAGACAGGGACTCTGGGACACCCGGTAACTCTCTGCACCACC +CCACGTCTCATGCAGAGCCCGGCCTGCGGCAGATGCTCCATCAGTTCATGGTGAATCCCT +GATAGCGTGGGATTGCTATACCTGGGCTCTTTCAGTGCCCACAACAGCCCTGTGAGATGT +AGATGCTGTGTTTATTTCCATTGAATGGGGAGGGAAACTGAGGCTCAGAGAGGGTTATTC +AGAGCCGTTGATATTTCCTCTGGCTGTGATGAAACAGCAGAGATTCTAACCCGGATTCCC +AAACCTGAACTCTGCACTGCTACATTGCCCTCCTCAACCAAGGCCTTTCCACTTCACTTT +TCTTTTTATTTTATTTTTTTTGAGACGGAGTTTCGCTCTTGTTGCCCAGGCTGGAGTGCA +ATGGCATGATCTTAGCTCACTGCAACCTCCACCTCCCAGGTTCAAGTGATTCTCCTGCCT +CAGCCTCCCAAGTAGCTGGGATTCAGGTGCCCGCCACCACACCCGGCTAATTTTTGTGTT +TTTAGTAGAGATGGGGTTTCACCATATTAGCCAGGCTGGTCTCGAATTCCTGAGCTCAAG +TGATCCTCTTGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCTATTGCGCCCG +GCCAATATATACCCATTCTGTCCAGGGTGTTCAAGCGTGTGTTTGAGAGAGTAGGATTTT +TTCTGGCCTCCAAGTTCAGGGGCACTGCCCGAAGGGCTGGCCTTAGGGTTAGTAGTTGAA +AGGGCAGAGACCTACATACCCAACAGTTGCAGAAATGCTGCAGCCCTGGGGGCCCGTAGC +ACCTTCTGTAGGGAGGGAGGGTATGTGACTGTGTCCTACTGACCCTGGGGACCCCGAGCT +GCAGTACCAGAACTCTGAGCAAGTTAGTGCCTGGAGGGCTCTTGGTTGTTTGTGGAAAGA +GTGGCATTGGAACCCCAGTTTCTTCTTCAGGAAAACTGGTTTATCAAACCCGTGAGTATC +AGACGAGGCAACTCTCCTAGAATGATTGATACCAGAGGCTGGGAAGGGTATGTGGATGTG +TGTGTTGCGGGGGGGCAGGGGAGGGCAATGAAGAGAGGTTGGTTAATGGGTACAAAGATA +GATACAGTTAGAAGGAACAGGCCAGGCACAATGCCTCAGACCTGTAATCCCAACATTTTG +GGAGGCCCAGGTGGGAGGATTAGTTGAGCCTAGGAGTTTGAGACCAGCTTGGGTAACATA +GTAAGATCCTGTCTCTATTAAAAAAAAAATTAAAAATTAGGCCAGGTACGGTGACTCACG +CCTGTAATCCCAGCACTTTGGGAGGCTGAGGTGGGCGGATCACTTGAGGCCAGGAGTTCG +AGACCAGCCTGGCCAACATGGCAAAATCCCACCTCTACAAAAAATACAGAAAAAATTAGT +TGGGTGTGGTGGTGTGTGCCTGTAGTCCCAGCTACTTGGGAGGCTGAGGCAGAAGAATCG +CTTAAACCCGGGAGGCGGAGGTTGCCGTGAGCCCAGATCATGTCACTGCACTCCAGCCTG +GGCGACAGAGTGAGACTCCATCTCAGAAAAAAATTTTAAATTACCCGGGCGTGGTGGTGA +GTGCCTGTAGTCCCAGCTACTGGAGAGGCTGAGGCGGGAATTGAAGGCTGCGGCGGGAAC +TCGAGGCTGCAGTGAGCTGTGATCATGCCACTGCACTCCAGCCTAGGCAACAGAGCAAGA +CCCTGTCTCCAAAAAAAAAGAAAAAAAAAAAAAAAAAGAAAAAAGGGGGAATAAAAGGGA +ATAAGTTCTAATGTTCAATAGCAGAGCAGAGTAACTACAATTAACAACAGTGTATTATAC +ATTTCAAAATAGCTATAAGAGAAGACTTGAAATGTTCTGTACACATAGAAATGATAAATG +CTTAGGCGACAGACACCCCAAATACCCTGGCACAATCATTGTAATTCTAGGCATGTAACA +AAATACCACATGTACCTCATAAATACACACAAATATTATGTATCAATAATTTTTAAATGT +TGCATATCTGAGGCTCATGAATCAAGATGAGAAAATAAAACCCTAAATACACATTGTTTT +AAAAGACCTTTTACAAACATGCACAAACACTCAGCAAGGGTTCATACCTCTTCCGTTTTC +TGTGTAGATGGTTTTCAGGAGAGAGCCCTTTCAGCCTACAGGAATAATGGAAGCCCATCA +CCTTTAGCTTGTACTAATTAGATCCCCCCAAGGAAAGCTTGTCTTAGCTTTTTCCCCTGA +TTTCTTTTCTTTTTTTTTTTTTCTTCCAGAGACAGGGTCTTACTCTGTCATCCAGGCTGG +AGTACAGTGGCACTACCTTAGCTCACTGCAGCTTCAACCTCCTGGGCTCTAGTGATCCTC +CCATGTCAGCCTCCCAAGTAGCTGGGACTACAGGCATGTACCACCACACCCAGCTAAGTT +CTTATTTCTTACACAGCCGAGGTCTCTCTGGGTTGCCCAGGCTAGTCCTAAAATACTGAG +CTTGGCCGGGCACGGTTGGCTCATGCCTGTACTCCCAGCACTTTGGGAGGCTGAGACAGG +CAGATCACTTGAGGTCAGAAGTTTGAGACCAGCCTGGCCAACATGGTGAAACCCCACCTC +TACTAAAAATACAAAAATTAGCCGGGCGTGGTGGCACATGCCTGTAATCCCAGCTACTTG +GGAGGCTGAGGCAGGAGAACTGCTTGAACCCAGGAGGGGGAGGTTGCAGTGAGCTGAGAT +CACGCCACTGCACTCCAGCCTGGGTGACAGAACGAGACTCTGTTTCAGAAAAAAAAAAAA +AAAAGACAGAGCTCAAGTGATCCGCCCACCTTGGCCTTGGGCTCCCAAAGTGCTGCGGAT +TCTGGGCGTAAGCCGCCATGCCCAGCCTTCCCCTGATTTCTTGAAACCATTGGTTCTGGC +TCCGCCCTCTAGTCCAGGGACCTCTTAGAACAATGATGTGTGTTTGACAAGCCACACCCA +CAGAACACTTGACATGTGGTTCAAAATTACGTGTCTTCATACCGAGGCAATAGGCTGGGT +TTAATCAGAGGTGGTCACTGACAGCATAAATGATCATAGCCCAGAAGTCCCAAGCTTGCA +AGAAAAATAAAGCCCAGAACCATATAATTTGGAGCTATTTATATTTAACATTTATGTCTC +TTTCTCTGGTGGAGAGAGGGGTTGATGGTGATAGTGATTCTGAAAGAATAGCAAAGATGG +AATGTTTCTGAAGAACATTTCACGTGGCATCAATACCAGCGATGTTCACTGAAAATGTCT +GTCCATATGTGCACATTTATTAGAAAAACATCGGTCAGGCATGGTGGCTCATGCCTGTAA +TCCCAACACTTTGGGAGGCTGGGGAAGGAGGATTGCTTTATTCCAGGAGTTTGAGACCAG +CCTGGGGAACATAGTAAAACCCCATCTCTAAAAAAATTTTAAAAGTTAGCCAGGCATGGT +GGTGTGCACCCTGAGTAGCTGGGACTACTCAGGAGGCTGAGGTGGGAGGATCGCTTGAGC +CCAGGAGTTTGAGGCTGCAGTGAGCTGTGATTGCACCACTACACTCCAACCCTGGCAGCA +GAGCAAGACCCTGTCTCTAAAATAAATAAATAAATAAAAACATGGTCATATGGGTGGACC +AAGCTGAAACTGAACATGTTATCCTTCTTTTATTTTATTTTTTTTTTGAGACAGTCTTGC +TCTGTTGCCCAGACTGGAGTGTAGTGGCACAATTTCAGCTGACTGCAACCTCCACCTCCC +AGATTCAAGTGATTCTCCTGCCTCAGGCTTCCGAGTAGCTGGGACTACAGGCGCGTGCCA +CCACACCTAGCTAATTTTTTGTATTTCTAGTAGAGACGGGGTTTCACTGTTAGCCAGGAT +GGTCTCGATCTCCTGACCTCATGATGCGCCCGCCTCAGCTTCCCAAAGTACTGGGATTAC +AGGCATAAGCCACCGTGCCCGGCTATCCTTTGTTTTAATGGTGCAATTTGAAGTTCAGCT +CAACAGCCATACTGGAGTCCTCTGAAGTCTGGTACCCCAAGAGCATGAGGCTTGGTATCC +AGGCCCATCACAGACCAGGAAGGGCCTGGTGGATTTCTCCCCACTGAGTGGGGTGGGCGG +CTTCTTGCTGTTGGAAAACCCTGATGCCTGTGCCGTTCTGAGAATCATATCGCAGCTCTG +GTAGCAACCGTGCTTCCAAAGTCATCCTCTAAGGCCACGTGAAGGTGCCAGCCTCATTTT +AATCACAAGCTGTATTTTATGAAGTTGTTTGTTTGGGTGTGGTGGAGCTGGGAACCATGC +CAAACCCCGAGAGCTTCCTGGAAATGACAGTTCTCATAGGAAAAGCAGCTCTTTTCTATT +TAAAACCTCTGTGGCGAGGGGAGGGGATCAGGCCCTGATTTGGTTCCCAAGCTACGTGTT +TGTATTTTTCTCGGTGTTTGAATATATCAGCTGGCATGTGTCTCATCCCTCAGACACGTC +TCCAATGATTTCACTTTTAATGGGCTTTGGCATTTAAAACACATGCGAATTGAGCTTTTT +GCTAATTGAGAAGATATGGAATGGAGAAATAGCCAATTAGGTATTGTGCTGCTTGTCTGA +CTTTTAAAACAGTTTCTCCCACTTCAGTGAAAGGTAGTCAAAGGGCCTCTCTCCAAGGAG +ACTTTTAGTTAGCTCTGAAAGAGTTTTATTTTAGCTTGGTCTTGTAGATTCAGGCAGAAA +GTGGGGCTCCCGTTCTCCCAGGTGTCAGACGAGGACCAGGTTAAAAGGAGAGCAGGATGG +GCTCAGGTTCCCACTTGGGGCATAACTGCATTGTCTGTTAGAACAAATGAAGGCAGAGCA +GGTGGTCGCCAGCCAGTTTGCGAGTCCGTGCCCAGCAGGTGCCAGCCCGCGTGCCCTGTG +CCAAAGCGCTTTTCTCTTGTAGCCCGCGGGCCTGGGCGCCCACAGCACAACCTGCTCCCT +GATGATTGGGCTCTTTGCCGTCGGCTCTGCTGCTTCTGTGACTGTCGCTGCTCTAGGCTG +TTGCCAAGGCAGGCTCAATTTTGCCCGGAGTGGGGAGGGGAGGTGCCGAAGAGTCTTAAT +TACCACTCAGCCACCTTGCCCAACTGCATTTGAAGCTGTTCCTTGACTTTTTCTTTAAGA +CAGGGTCTTGCTCTGATGCCCAGGCTTGAGTGCGGTGAGATCATAGCTCACTGCAGCCTC +AAACTCTTGCCCTCAAGTGATCCTCCAGCCTCAGCCTCCTGAGTAGCTGGGACAATAGGT +GTGTGCTACCATGCTCAGCTAATTTTTTTTTTCTTTTCACTAAAAGACTTTAAATTCTCA +CTTGGGAAAGGACAGTAAGAAGGGGTAAATCAGTTGGCATAGCAGCTCGCAGGCGCCATG +TGAATTATCTGTGGAACGTTGGATGGATAGACGGTTGATAAGTTGGTTTTAGCCACCGAG +AGTAGTTGAGAAAAGCAGGAAGAAATGTGTTTTGGTGTAAGCCCAATCAAGCCATTCTTA +ATCCCTGCATACAACTGCATAGCCAAAGTTGGCTCATGGCACTGGCAAGTCAGCCCTTTC +TGAGTGCGATTCCTGATAAGATGCGACCCTGAGTGTGTGGCCTGGAGAGGGCTGTGAGTA +CGAGCACAGGCTCTGGAGTCAGAGAGCTGGAGCTCGGACTCCCCTCTGCATTGTGAGGAC +CCATCTGTGGTCCTTGGGCAAGTTCCTAACCTTTCAGAGCCTCAGGTGCCTCATCTGCAG +AATGGGAGCATATTCATTTCCTGTTGCCACCATAACCCGTTGCCACAAACTTGGCATCTT +AAAGCAGTACCCATTTTTGATCTCACTGTTTGGTAGGTGAGAAGTCAGTGCTAGCTGGGG +CCGGCGTCTCTGTTCTGGGTTTCACAAGGCCAGAATCAAGGTCTTGCTGGCTGGGCTCTT +ATCAGGAGGCACTGGAAAGAATCTACTTCCTTGTTCCTTCAGGGTATTTGCAGATTGCAT +TTCCGTGTGATCATGGACTGAGATCCTGTGTCTGTTGGCCAGGTGTCCTTCTCAGCTTCT +AGAAGCTGTCTGTGTTTCTCAGCTCATGGCCACCACTGGTGGCCCAGGTTCTCCTCATGC +CTTGAATCTCTGGCTTCCCTTCTTCCTCCTCTTTCCTGTTTTTCTCTTCCACTGCTTGTC +TCTGATTCTGGTCGGAGAAATGCTTCTGCTTTTAAGGGCTCCAGTGATTCGAGGGCCCAC +TCAGGTCATCTAAGATATGCTCCCTACCTTAATTCCATCTGCAGTCTCTCCACAGCAGCA +CCGGGATTCATGTTTGAATAACGGGAAGGAATGCTGGGGGACACCTCTAGAATTCTATCA +TGGGCGGTTAGGAGTGTACCTGCCACGGAGCTGTCATGAAGGTTAAATCACGCGAGTTGT +ATAAAGCACAGAGCAGAATCCCTGGCACACTCTTAAGGGCTCTTACACGCATTCACTGTC +AGGGAGCAGACATGAGACTCTTGGCAGCACTGATGTTGTGCAGATGTGGGATCTGCCGTG +GCCCCATGGGCTTCCTGAACAGCAGGTACCCACCTGTTGATGTGGCTTTTCCAGGGGCCT +TCGTTTACCTTGGGGAAGTTGTATCCTCTCTCCTGGGCCTGGTGTTGCATTCTGGAGATT +TATTTTCCCTTTTGTCTTTATCACTCAAAGCTGGAGTTCAGGTTCGGTCTGCCGTGACAC +TGTGGTTAGACTTTTTTTGGCAAGATACCTCTCACATCAGATGATTGAGCAAGAAAGGAA +AGATCTGATGTCAGCGTGTAAAGGCTGGATATGGGCACCAAGGATTGGGGAGCTCAGTTC +GGGAGATGTGTTTTGGTCTTTATTACCGGCAGCCCAGGGGCAGGAATACTGACTGCAGCT +TTGGGTAGTTTGAGGACACATCTGAAAGAGGTGAGCTGAAGCCTTTCAGTTTTCAGCTGT +ACTTGCATTAAAGCAAGGCTTGTCCCTGCTGGGGTACCCTTCATTCCTCGACCTCACTGA +CTGGTGAGTTTCTTCCATTTCATGAGTAATGACCATCTGTGGGCACAGAGCTTCGTCATC +TTACTGAATCCCCGCCCTTTGCAGGGGTGACCTTACTGTCACTTACAGATGAAGCAGCTG +GGACTTTGGGAGGTTCAGCAGCTTGCCCTACAGCAAATACATGGCAGAGCTGGCACTGGA +ACTCAGGCATGACCTACCCCAGAGTCAGCACTGTCCACAGCATCTCTGCGGGGCACGGCC +TGAGCCCCAGTGCAAGGCAGTAACCTCCCTTTTCTGTTTCAGGCCCTGAAGCGCCAGAGC +TCGTTGGGCCTTTCCTTCTTTAACAGCATCTTGGCCCATGGGGACCTACGCAACAACAAG +CTCAACCAGCTCTCCGTCAACCTGTGGCACCTGGCACAGAGGCACGGCTGTGCAGACACC +AGGACCATGGTGAGGCGCTCGGAGGGCCCCGTGGTATAAGCCCACTGGCCAGTGCACAAC +CACCCTCAACACAGCATTGTGGCCTGGACATCAGACAGACAACCCCATACTCCCCTTTTA +GAAAAGCACTTGGTCCATTTCTACTGGATCACTTCCTAGCAGTAAAAAGCAGAGCTGGCC +AGGTGTGGCAGCTCATGCCTATAATCCCAGCACTTTGGGAGGCTGAGACAGGAGGATCGC +TTGAGGCTAAGGGTTTGACACCAGCCTGGGCAACATAGTGAGACCAGGTCTCTACAAAAA +ATAAAAAATTAGCCGGCCATGGTGGTGCACATGTGTAGTCCCAGCTACTCGGGAGGCTGA +AGAGGGAGGATGGCTTGAGCCCAGGAGTTCGAGGCTGCAGTGAGCTATGATCACACCGCT +GCACTCCAGCCTGGGTGATAGAGCAGGACCTTGTCTCCAAAACAAAGAACAAAAGCATAG +CCTTAAAAGTCTATTCCCTCTGAATAGGAACCATACATACAAAACATCAGTCATTTCTGG +TCACGTCCAAATCTGATTTTTAGGGCAAGCTGCAATCCAAGAAGTTGAAGACTTTGATTT +CTTCCCTCCTCTCATCCCTCAAAAAACTCACTCTTCTCTGCTAAGAAATCTAAGCTCACA +TAATGGCTGATTCATTAGAGCCTTGGGCTCCAAGGATAATGAACCAGAAAGGAGATGGAT +CTTTCTTTTTCCTCATAGGTGAAAACGCTAGAATACATCAAGAAGCAAAGCAAACAACCA +GACATGACTCATCTGACGGAGCTGGCCCTCAGACTCCCTCTGCAAACAAGGACCTGACCC +CCGGGCCCATCCCCAGGCTCAGGGACTCTGGTGCCAAATCCAGAAAGATCTGCTCTGCTG +CCCTGAACTCTTACGGCAATTTAGGTTTCTCATTTTTCTTTTCTTTTTACATATGTACAA +ATTGTTTTAAGCTTTGGCCTCTATCCAGGTTATTCTGACAATGAAGAAATGGGAGTTGTC +AGAGCATTAAAATGCAATCTTCACTAAGAAGCAGTCTCTGTGTTGTCTTTGCACAAGTGG +CCTTCGGTCTACTCAGCCCGATCTGATGGGCCTTTTTAGCAAGAGAGAAACAAGAATGCA +AGTAACATCTTTCTTCTCTGGAAGGTGTTTGTTTTTTCATAGTTTAGAAATAAGGACTTT +AAAAGTGGACTGCTTTTCAAAGTGCCACTGTTCCAGACCCATTCCATTCCAGACTTTGTA +CCTTAAAGTTAGAGCACACCCAAAGTCTGGAACTGTGTTACCTGAACCCCTATGGAGGAT +TTATAAAAGGCAGAAATAGCACTCCATTAACTCTTTTTCCTATCAAAAGCAGCTCTTGAT +TGGACTTAGAATCTGTGTTGGTGGATCAAAGGAGAAAGCGAGGTCAAATTTGAGATTCTC +TGTGGCTTCAGTATACAGTAACTGAATAAATGTCCTGAAGGAGCATTTATGTTCATGACT +GTTCATTTAATTACTTCTGACTGTCTTCCTCCAGAAGAGAAAGACCGTGTCTAAATATAT +TATCCTGGTTTGTTTTGCAGCCACAATTCTAAACAGCATGTGATTCTGTCTGCTTTTCTT +CCAACAGTTTGGTGGAACCTGATTCTTCTATTACGGCTGGTGAGCTTGCACCGACATTTC +ATTTTGAATCAGTAAAAACATTCATACTGATGGGTGATTCATCATCTCAGCCACTGCCAT +TATGAAAATGCATCCACACTGTGGATTAAAAATGCCCCAAACTATTGTGCTTCTACAAGA +TCCACACTGGAACTGGACATAGATTACATTTCATCTTTACTCTGAGAAATACAAGACTAC +AGTTGAACACTCAGTTAACCTCAGACAGTAAAAGGGGCTAAAAAATTTTTTTAAATCAAT +TTATTGGCCGGGCACGGTGATTCACGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGCAG +GCAGATCACCTGAGGTCAGGAATTCGAGACCAGCCTGGCCAACATGGTGAAACCCCGTCT +CTACTAACAATACAAAAATTAGCCAGGCGTGGTGGCACACACCTGTAATCCCAGCTACTT +GGGAGGCTGAGGCAGGAGAATCGCTTGAACCCAGGAGGCGGAGGTTGCAGTGAGCCGAGA +TTGCGTCACTGCACTCCAGCCTGAGTGACAAGAGCAAAATATCATCTCATCTCAAAAAAA +ATTAAAGGACAGCAGACACTAATGAATGCTTCTTTCCCTCCCCTCTACTAAATCATACAG +AAACTCAGACAGCATTGTGGGGTGGCTCAGATACTCCCAAGTGGCCTTTATTTCACAAAA +TTCTGTTTTTTTTTCTTTTTTTTGAGACAGTTTCACTCTTGTTGCCCAGGCTGGAGTACA +ATGGCGTGATCTCGGCTCACCCCAACCTCCGCCTCCCGAGTCTAAGCAATTCTCCTGCCT +CAGCCTCCTGAGTAGCTGGGATAACAGGAGTGCGCCACCACACCCAGCTAATTTTGTATT +TTTAGTAGAGATGGGGTTTCTCCATGTTGGTCAGGCTGGTCTAGAACTCCTGACCTCAGG +TGATCCGCCGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTAAGCCACCGCACCTGG +CCCACAGAAGTATTTTCATTAAAATTATTTTATCTACTTTTACTGTGTGATGCTATAAAA +TGAAAAACAATTGGCAAATTCACAAATTATGTTCTTCAAGTCATTTCTTCTCCTCTGAGG +CTGAACGTGGTGGGCAGCATTAGTTCCCAAGCCTAGGCCAGTGAATTCTTACCGCTCTCA +CATTACACCTGAACTTGGACTTTCACATGAGGTCGGGCACCCATTATATCAAAGGTGCTT +CTGAATCCTGTCATGTGGCCCAGGCAGAGGCTTAGATTTTATATGTCCTTGTGTGTGCAG +TTTCCCCCAGCCCTTTACTGAATCAATAAGCCGGTCTCTGAAAACACTGGTCTATGTGAG +ATGAAGTCTATCATTAGCAAGGATGGAGCAATAAGATGTCAGCCAGAATTGTAGAAAATA +AAAATGATGGGGCCTGGGTGCGGTGGCTCATGCCTGTAATACCAACACTTTGGGAGGCTG +AGGTAGGTGGATCATGAGGCCAAGAGATCAAGACCATCCTGGCCAACATGGTGAAACTCC +ATCTCTACTAAAAATACAAAAAAAAATTAGCTGGGTGTGGTGGTGCTCACCTGTAATCCC +AGCTTCTCAGGAGGCTGAGGCAGGAGAATCGCTTGAACCCTGGAGGTGGAGGTTGCAGTG +AGCTGAGATCACGCCTCTGCACTCCAGCCTGGGCGTGGAGTGAGAGTGAGACTGTCTCAA +AAAAAAAAAAAGAAAGAAAAACAAAACCATGGCAACTTCCACATGAGACTTACTTACATT +AGGTCTTCTATTGTTACTTTAACAAATTGCCACAATTGTAGCGGCTTAAAACATAATGTT +GTCATCTGACGGTTCTATAGGTCTTAAGTCCGCCTGGTCTCACTGAGCTAAAATTAAGGC +ATCAGCAGGGCTACGCTCCTTCTGGGAGGCTCTAGGGGAGAATCTACTTCCTTGCCTTTT +CCAGCTTCTAGACAGCACACACATTCCTTGGCTTCTGACCCTTCCCTTCCCATCTTCAAA +ACCAGCAGTGTCTAGTCAAGTCTTTCTTAAGTCTCTTTGATGTGGACTCTTTTTTGCCTT +CCTCTTCCACATTTAGGGATCTTTGTGATTCCTCCGGCCCACCCAGAAACACGGGATCCT +CTTCCTGTTTTAAGGTCAGCTGATTAGCAAACTTAATTCCCTTTTGTTTCGTAACCTAAC +AAATACACAGGTTCTGAGGAGATGTGGTAGGAAGGGGTGTTATTCTGCCAACTTCTTTTG +TGAGGACTGTGTCTATTTGGCAAATTTTTTTTTTTTTTTGGAATGGGGTCTTGCTCTGTC +ACCCAGGCTGGAACACAGTGGTGCAATCATGGCTCACTGCAGCCGTGATGGAGGGTGGTG +CTCAAACCAATGTTAATTTACAAAGGATGGGAGCTCAGAGTGATTCTCCCAAGACAAGAC +TGCCAGAGGGTGGGGTCCTGCTCATCTGAGAGATGGTGATCTGCACTGGCAGAAAGCAAA +AGGACAAGATTAAGTCCATTCTGAAGACACCCAGCATTGTGGTGTCTTGGCTGCCCAACC +TCCACTGGTGAGACGTAAAGTTCTTATGTATATAGAAAAGCAATAAAGCTCCCCCTGTGC +AAATGGAACTCCTAAGCCAGTGGTGATGTTGAGTTAGAAAGTCACAGCCTATTACAGACA +GAATTTACACCAGGGGCAAGGCCTGACCATCACACCCTCATGAGAGCTACCAGTCACCAG +GGCTTGGATGGGAGCAACACAGCGGACATATGATCACCTCTCCACAATCACCCAAAGACA +GTTTTTTTTTGTTTGTTTTTGAGACAGAGTCTCATTCTGTTGCCCGGGGCTAGAGTGTGC +AGTGGCACCATCCCAGCTCACTACAACCTCCACCTCCCGGGTTCAAGCGATTCTCCTGTC +AGCCTCCTGAGTAGCCGGGATTACAAGCCCGTGACACCACACCCACCCAGCTAATTTTTG +TATTTTTAGTAGAGACGGGGTTTCACCATGTTGGTCAGGCTGGTCTCGAACTCTTGACCT +CGTGATCCGCCCACCTTGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGTCACCGCACC +TGGCAGAGCACAACCTTTTTAACAGAGCTAAGGCAGGCCAACGTCAGGGTGACCTCTTGG +CAAGATAAAAACTATGAGTAGTAAACGGCCGATTCCAGCTACTCAGGAGACTGAGGCACA +AGAATCGCTTGAACCCAGGAAGCAGAGGTTACAATGAGCCGAGATCACGCCACCACACTC +CAGCCTGCGCGACCGTGAGACTCCATCTCAAAAAAAAAGAAACGAACGGCTGGTTCCTGT +TTACACCAGGCACATTCCTGTAGTGTTGCTCAAGGTCAGGAGGGATTTGTTTCTCCATCA +AAGGAGGAGGTGCCCAGAAGGCACTCACTCAAATCCAGAACACTGCCTCTTGGGCTTTCC +ACGGCCTCTCCCATTATGTATCTCAAGGTTGAATCCAGGAAAGAAAGGCAGGACAAGTTC +ACGTCCTGAGGGAAGTGGCCCAAGTAGGTCCTTGTAGCACATACTTGTCCAACTATTGAC +CTGGCCAATGCTTGCGGATCAGGGTTCAGAGCCAGGGAAACTGCCTGAAGTGCCTGCCTC +ACCTCTGCCCAATGGGCAGCTGTGGACACCATGGCCACTTCACCAGCATCCACTCTTCTT +GACTGAAGGGAATCACCAGCCTTCCCATGACAGGGGCGGGTGCAGCTATGGGCAGATGAC +TCATTGCCCAGCAATGGAGGCTTCTGGAAGTTTCCTTGAGACACAAAAAGGCTTTTCTTC +CTCTGGAATGTTCTAGGGTCTTGATATGCTGCCTGGAACTGTTACTGCCATCTTTGTACT +AGCCTTGATGAAGCCAACACTGGAGATGATGGAGAGAATGCTTCCTTGGCGAGCTGTTGA +ACCAGGCCCTAATCAGGCCTTCCTGCCACGTGAGACTGAACTTTCTGGCCATCGAGGCCT +GCCTGGGCTGGGATGTCTGTAGGAGGCATGTTCAGGCCAAACGATCGTGAAAATGTCCCA +GTCAGAACCTGTATTTTGGGATGCAAAAAGCTAGGTGAGTGGAAAGAAGGTGGTCACAGA +TGGTCACATGCGACTTGGGCCACTGGACCTGGAGCTCTTTGAGGCTTGCTGTAGAGTCCA +GGCTTGGAAACGCTGTCCCCACAGCCGATGAGGCAACTTCCCGTGTCATCTCCACACGTT +CATCTCCTCCTGGCATTCAATATCCACCTACAGAAGTCACCTGGGATTCTCTTCCTTGTG +ATAAAAAAGAATCTCATCAGACACATCCCTGGGGCTGGGCACAGTGGCTCACACCTGTGA +TCCCAGCTCTTGGGGGCTGAGGCAGGAGCATGAGTTGAGTCCAGGAGTTTGGGACTAGCC +TGGACAATATAGTGAGACCCCATCTCTACAAAAAATTTTAAACACTAGCTGGTTGTTGTG +GTGCACACCCACAGTCCCAGCTACTTGGGAGGCTGAGGTGGGAGGATCACTTAAGCTGGA +TAGGTAGTGGTTGCAACAAGCCGTGATATGCCACTACACTCCAGCCTGGGTGACAGAGTG +AGAGCCTATCTCAAAACACACACACACGTCCCTGGGATCTGCCATTGATTCATTTGCGGG +ACTAACCACTCTTCCTAAAATGCCTTGTTCAGAATCCAGTCAAAGCACAAAAATCCTACC +TCAGCACTTAGGGCCGAAGGGACACCAGTGGAAAAGGCAGGACTGGTTTAGAGGCACATT +TCCCAGCAGCAGCAGCTCAGTCACATGTGTTTGGTAACAACTCAGACACCTCTCTGCCTA +CAGCTGCTCTATGACAGGGGAAAGGAAAAGGAAGGAAAAGGAGTTTGCGATTCTCCGTTC +CTCATTCACTCCACTTTTTATCAGAGATGCAGACTTGTCATAAAACTTTTTCCTCCATCT +AAAGACATTTCAATCCCCAACGAGGATTCTGGTGGAAATTCCCTAAAGGGGACATTCAGA +GTGGCGAATAGTGAACTTAGGGCTTCGGGTACAAAAGTACAACACCCTGCACTTAGTGGC +TGGGTGACCCCAGGCAATTTTATTACTTTATCCCTGAACCTCAGTTGCCTCATCTATAAG +ATGGGGCTAATAATAGCACCCATTTCATAATTATGAAGATTAAATACATTAAGGAAAACA +CTAGTATGTCCCTAGTACCTGCTAAACACTCAACAAAAGTTAACTGTACATACTGATGTC +TCAAACAGGGACGGAATGTTTAACACAGAAAACAGGAGGTTTTAGCACTCACTCGTTCTC +CTGGCTCCCGAAATATGAGCTGCCCTGCCCCAGTTCATCCAAGCCCATCAATATAGTTGT +CCTCGTCCTTAATCTCCACAGGTGTTCAATGTGAGCCAACTGTCAGATGGCTTTCATTTG +CACAACTGAATAAACCATTTATGCCTAGTGTTCCATTACTGGAACGCTAAGCTTATGGGA +GTTATTTATATCTTACTGCTCGAGGTCCTCACCA diff --git a/test/csq/ENST00000448695/ENST00000448695.fa.fai b/test/csq/ENST00000448695/ENST00000448695.fa.fai new file mode 100644 index 0000000..5e13362 --- /dev/null +++ b/test/csq/ENST00000448695/ENST00000448695.fa.fai @@ -0,0 +1 @@ +16 151594 25 60 61 diff --git a/test/csq/ENST00000448695/ENST00000448695.gff b/test/csq/ENST00000448695/ENST00000448695.gff new file mode 100644 index 0000000..5c784a7 --- /dev/null +++ b/test/csq/ENST00000448695/ENST00000448695.gff @@ -0,0 +1,55 @@ +16 ensembl_havana gene 21 151574 . + . ID=gene:ENSG00000103544;Name=C16orf62;biotype=protein_coding;description=chromosome 16 open reading frame 62 [Source:HGNC Symbol%3BAcc:24641];gene_id=ENSG00000103544;logic_name=ensembl_havana_gene;version=10 +16 ensembl_havana transcript 23766 145465 . + . ID=transcript:ENST00000448695;Parent=gene:ENSG00000103544;Name=C16orf62-203;biotype=protein_coding;tag=basic;transcript_id=ENST00000448695;version=1 +16 ensembl exon 23766 23909 . + . Parent=transcript:ENST00000448695;Name=ENSE00001647011;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00001647011;rank=1;version=1 +16 ensembl CDS 23766 23909 . + 0 ID=CDS:ENSP00000398009;Parent=transcript:ENST00000448695;protein_id=ENSP00000398009 +16 ensembl exon 26306 26434 . + . Parent=transcript:ENST00000448695;Name=ENSE00003583820;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003583820;rank=2;version=1 +16 ensembl CDS 26306 26434 . + 0 ID=CDS:ENSP00000398009;Parent=transcript:ENST00000448695;protein_id=ENSP00000398009 +16 ensembl exon 32174 32179 . + . Parent=transcript:ENST00000448695;Name=ENSE00001690913;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00001690913;rank=3;version=1 +16 ensembl CDS 32174 32179 . + 0 ID=CDS:ENSP00000398009;Parent=transcript:ENST00000448695;protein_id=ENSP00000398009 +16 ensembl exon 46450 46504 . + . Parent=transcript:ENST00000448695;Name=ENSE00001713400;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00001713400;rank=4;version=1 +16 ensembl CDS 46450 46504 . + 0 ID=CDS:ENSP00000398009;Parent=transcript:ENST00000448695;protein_id=ENSP00000398009 +16 ensembl exon 52959 53055 . + . Parent=transcript:ENST00000448695;Name=ENSE00003631395;constitutive=0;ensembl_end_phase=2;ensembl_phase=1;exon_id=ENSE00003631395;rank=5;version=1 +16 ensembl CDS 52959 53055 . + 2 ID=CDS:ENSP00000398009;Parent=transcript:ENST00000448695;protein_id=ENSP00000398009 +16 ensembl exon 53755 53802 . + . Parent=transcript:ENST00000448695;Name=ENSE00003682253;constitutive=0;ensembl_end_phase=2;ensembl_phase=2;exon_id=ENSE00003682253;rank=6;version=1 +16 ensembl CDS 53755 53802 . + 1 ID=CDS:ENSP00000398009;Parent=transcript:ENST00000448695;protein_id=ENSP00000398009 +16 ensembl exon 55103 55196 . + . Parent=transcript:ENST00000448695;Name=ENSE00003516770;constitutive=0;ensembl_end_phase=0;ensembl_phase=2;exon_id=ENSE00003516770;rank=7;version=1 +16 ensembl CDS 55103 55196 . + 1 ID=CDS:ENSP00000398009;Parent=transcript:ENST00000448695;protein_id=ENSP00000398009 +16 ensembl exon 60895 60972 . + . Parent=transcript:ENST00000448695;Name=ENSE00003547874;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003547874;rank=8;version=1 +16 ensembl CDS 60895 60972 . + 0 ID=CDS:ENSP00000398009;Parent=transcript:ENST00000448695;protein_id=ENSP00000398009 +16 ensembl exon 61467 61589 . + . Parent=transcript:ENST00000448695;Name=ENSE00003596287;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003596287;rank=9;version=1 +16 ensembl CDS 61467 61589 . + 0 ID=CDS:ENSP00000398009;Parent=transcript:ENST00000448695;protein_id=ENSP00000398009 +16 ensembl exon 70958 71004 . + . Parent=transcript:ENST00000448695;Name=ENSE00003589693;constitutive=0;ensembl_end_phase=2;ensembl_phase=0;exon_id=ENSE00003589693;rank=10;version=1 +16 ensembl CDS 70958 71004 . + 0 ID=CDS:ENSP00000398009;Parent=transcript:ENST00000448695;protein_id=ENSP00000398009 +16 ensembl exon 72475 72586 . + . Parent=transcript:ENST00000448695;Name=ENSE00001667879;constitutive=0;ensembl_end_phase=0;ensembl_phase=2;exon_id=ENSE00001667879;rank=11;version=1 +16 ensembl CDS 72475 72586 . + 1 ID=CDS:ENSP00000398009;Parent=transcript:ENST00000448695;protein_id=ENSP00000398009 +16 ensembl exon 73418 73534 . + . Parent=transcript:ENST00000448695;Name=ENSE00001740172;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00001740172;rank=12;version=1 +16 ensembl CDS 73418 73534 . + 0 ID=CDS:ENSP00000398009;Parent=transcript:ENST00000448695;protein_id=ENSP00000398009 +16 ensembl exon 74548 74601 . + . Parent=transcript:ENST00000448695;Name=ENSE00001653861;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00001653861;rank=13;version=1 +16 ensembl CDS 74548 74601 . + 0 ID=CDS:ENSP00000398009;Parent=transcript:ENST00000448695;protein_id=ENSP00000398009 +16 ensembl exon 77873 77953 . + . Parent=transcript:ENST00000448695;Name=ENSE00001650977;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00001650977;rank=14;version=1 +16 ensembl CDS 77873 77953 . + 0 ID=CDS:ENSP00000398009;Parent=transcript:ENST00000448695;protein_id=ENSP00000398009 +16 ensembl exon 82375 82437 . + . Parent=transcript:ENST00000448695;Name=ENSE00001669194;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00001669194;rank=15;version=1 +16 ensembl CDS 82375 82437 . + 0 ID=CDS:ENSP00000398009;Parent=transcript:ENST00000448695;protein_id=ENSP00000398009 +16 ensembl exon 84796 84881 . + . Parent=transcript:ENST00000448695;Name=ENSE00001665698;constitutive=0;ensembl_end_phase=2;ensembl_phase=0;exon_id=ENSE00001665698;rank=16;version=1 +16 ensembl CDS 84796 84881 . + 0 ID=CDS:ENSP00000398009;Parent=transcript:ENST00000448695;protein_id=ENSP00000398009 +16 ensembl exon 87177 87257 . + . Parent=transcript:ENST00000448695;Name=ENSE00001804934;constitutive=0;ensembl_end_phase=2;ensembl_phase=2;exon_id=ENSE00001804934;rank=17;version=1 +16 ensembl CDS 87177 87257 . + 1 ID=CDS:ENSP00000398009;Parent=transcript:ENST00000448695;protein_id=ENSP00000398009 +16 ensembl exon 89667 89730 . + . Parent=transcript:ENST00000448695;Name=ENSE00001634343;constitutive=0;ensembl_end_phase=0;ensembl_phase=2;exon_id=ENSE00001634343;rank=18;version=1 +16 ensembl CDS 89667 89730 . + 1 ID=CDS:ENSP00000398009;Parent=transcript:ENST00000448695;protein_id=ENSP00000398009 +16 ensembl exon 92565 92663 . + . Parent=transcript:ENST00000448695;Name=ENSE00001614851;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00001614851;rank=19;version=1 +16 ensembl CDS 92565 92663 . + 0 ID=CDS:ENSP00000398009;Parent=transcript:ENST00000448695;protein_id=ENSP00000398009 +16 ensembl exon 95163 95240 . + . Parent=transcript:ENST00000448695;Name=ENSE00003460599;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003460599;rank=20;version=1 +16 ensembl CDS 95163 95240 . + 0 ID=CDS:ENSP00000398009;Parent=transcript:ENST00000448695;protein_id=ENSP00000398009 +16 ensembl exon 96757 96871 . + . Parent=transcript:ENST00000448695;Name=ENSE00003580628;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00003580628;rank=21;version=1 +16 ensembl CDS 96757 96871 . + 0 ID=CDS:ENSP00000398009;Parent=transcript:ENST00000448695;protein_id=ENSP00000398009 +16 ensembl exon 113941 114080 . + . Parent=transcript:ENST00000448695;Name=ENSE00001599382;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00001599382;rank=22;version=1 +16 ensembl CDS 113941 114080 . + 2 ID=CDS:ENSP00000398009;Parent=transcript:ENST00000448695;protein_id=ENSP00000398009 +16 ensembl exon 127006 127171 . + . Parent=transcript:ENST00000448695;Name=ENSE00001690657;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00001690657;rank=23;version=1 +16 ensembl CDS 127006 127171 . + 0 ID=CDS:ENSP00000398009;Parent=transcript:ENST00000448695;protein_id=ENSP00000398009 +16 ensembl exon 136134 136252 . + . Parent=transcript:ENST00000448695;Name=ENSE00001730354;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00001730354;rank=24;version=1 +16 ensembl CDS 136134 136252 . + 2 ID=CDS:ENSP00000398009;Parent=transcript:ENST00000448695;protein_id=ENSP00000398009 +16 ensembl exon 144283 144429 . + . Parent=transcript:ENST00000448695;Name=ENSE00001672058;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00001672058;rank=25;version=1 +16 ensembl CDS 144283 144429 . + 0 ID=CDS:ENSP00000398009;Parent=transcript:ENST00000448695;protein_id=ENSP00000398009 +16 ensembl CDS 145159 145257 . + 0 ID=CDS:ENSP00000398009;Parent=transcript:ENST00000448695;protein_id=ENSP00000398009 +16 ensembl exon 145159 145465 . + . Parent=transcript:ENST00000448695;Name=ENSE00001715916;constitutive=0;ensembl_end_phase=-1;ensembl_phase=0;exon_id=ENSE00001715916;rank=26;version=1 +16 ensembl three_prime_UTR 145258 145465 . + . Parent=transcript:ENST00000448695 diff --git a/test/csq/ENST00000448695/syn-and-splice-reg.txt b/test/csq/ENST00000448695/syn-and-splice-reg.txt new file mode 100644 index 0000000..6d1b666 --- /dev/null +++ b/test/csq/ENST00000448695/syn-and-splice-reg.txt @@ -0,0 +1,3 @@ +32176 T C splice_region|C16orf62|ENST00000448695|protein_coding,synonymous|C16orf62|ENST00000448695|protein_coding|+|92A|32176T>C +32176 T C splice_region|C16orf62|ENST00000448695|protein_coding,synonymous|C16orf62|ENST00000448695|protein_coding|+|92A|32176T>C + diff --git a/test/csq/ENST00000448695/syn-and-splice-reg.vcf b/test/csq/ENST00000448695/syn-and-splice-reg.vcf new file mode 100644 index 0000000..47f7b57 --- /dev/null +++ b/test/csq/ENST00000448695/syn-and-splice-reg.vcf @@ -0,0 +1,7 @@ +##fileformat=VCFv4.2 +##contig= +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO +16 32176 . T C . . EXP=splice_region|C16orf62|ENST00000448695|protein_coding,synonymous|C16orf62|ENST00000448695|protein_coding|+|92A|32176T>C;type=ENST00000448695:19598717-T-C, VEP thinks this is not splice region, why? diff --git a/test/csq/ENST00000479739/ENST00000479739.fa b/test/csq/ENST00000479739/ENST00000479739.fa new file mode 100644 index 0000000..4827bf5 --- /dev/null +++ b/test/csq/ENST00000479739/ENST00000479739.fa @@ -0,0 +1,813 @@ +>2 2:217710-266418 +GGAGCTGGGGCTGAGCGGGCAGCTCGCTTCAGGGTGGGCATGGGGGAGCGCAAATATTGG +GTCAGCGAGTGTCTGAAAGGCAACAGAATCTCTGGTGGATTTAATAGAGGGCATGAGATA +GAAGAACGAAAGTTGGCTCTGAAGTCACCCTGAGGACCAAGGAAATCCAAGGATGGAATT +TCCATTTACTGAAGAGGAACACTGTGGGAGGGGCAGGCTAAGTGAGGAGAAAGAAGAGCT +TGGATTTGAGCCCGTGAAGGCTGAGGTGTTGTTCCTTGTCCAAACGGAGCTGTAAAGTGC +ATAGCTGGAGAGGGGAGTCTAGAGTTCAGGAAGGAGCTCAGGCAGCCCAGAACGGAGGTG +GATTTCACCCTGCATATGAGACATAGGACTTCTGCCTACCTTACAAAAAAAATAAGAAAA +ACAAAATTGAAATATTAACTTAGTAAACATTTAAAAATTTTATTTAGAGACAAGTCTACC +ATGTCACCGTAAGTTTATGCTACTGCTGGAAATGAACAAATGTAGCCCCATAAGGAAGAA +AAGTTGAGAGATGCCATATGTTTAAAGACATGGTAGTCAGACTTCTTTGTAATCACATTT +CTATGATAAATGCATAGTATAATTTTTGAAGGTATAAAGACAATTTCTAAGGATTTATAT +TCTAGTTAATACCTACGACTCTAAACATTACTTAATACCTCATTTAAGCTGATTTCTTTT +TCTCTAGTCACTTTGCAAATGGAAATGTAAGAATTGAAATTTGTGGCTCTACCCTCAAGA +TTCTCAAATTAAAACACAGCTACCATATACATGGCCAGATCAAATGCTTAGCGATGTTTG +AAGTGTTCACAAGAGAACTATGAGCGTATAAACTGTATGATATTCTATGACACAGTAAGT +GTGATAAAGTTAGTACAAAGTATTTAAAGATATGTCAGTCAGCTCTTTTTATATAGAAAA +ACAAAATCTTTTACATACGGAATGGAAATTTTGTAGAACAGAAGTTTTTTAAAATTTATA +TTAAACATTGCTTAACTAGTAAATCCTGTCAGTGTAGAAATAATTTTTTTGTAATTCTCA +AAGAAGAAAATAGTATACGCTTTAATTCATGGTTACGTAGTTGGCTGGAAAAATGCCAGT +TTGACCTCGAAGTTTTCCTTCCCACCAATCAAAATGTGAATCTGTTTTTGATATAACTGT +GATTCTGTCTCCAGCTTGAAAATTCAAATCCCCAGGCTGCTGTCCTTCAAATGAATACAG +CGCTGTCACTTCTATGGGTTGATTCAAATTGCCTGAAACAAGAAAAAAGTATTCACGTTT +ATGTTCTTTAAGGGAGAAATTGGGGGTATCTGCTGGTAAGATAAAAATTAACCACTTAGG +GCTTGGCATGCTGATGTCTTGGAGGCTGGCAGAAACCACAACAGTCTGTGTAATTTTCAT +CACATTATTAAACTTATTTTTCTCTGCACATTCTATACCTAAGGATTTAGCACATGCTTC +TGGTTACAATCGTCTAAATTTTGAATAATCTATGAGATAATACAACTTACATTTTTTCTA +TTTTAATATAGTCATTGCTGTGGTCTGAATGTCTGTGTCCCCCTGAGATTCAAGTGTTGA +AATCCTCAACCCCAAGGTGATGGTGTTAGAAGTGGGGTCTCTGGGGGCTGATTAGGTCAT +TACGTTTCCCCCTCATGAATGGGATCAGTGTCTTACAGACAGAGCCTGAGGGGAGCTTCT +TGCACCTTCCTCCTTGTGAGGACACAGCCAGATGGCACCATCTCTGAGGCAGAAACCGAG +ACCTTGCCAGACACTGAGTCTCCTGGAACCTTGATCTTGGAATCCAGCCTCCAGAAGCGT +GAGAAATAAAATTCCATTGTCTATGAGCTGCCCAGACTATGGTGTTTTGTTACAGCAGCT +GGAAGGGGCCAAGATAGTGTGACAGTTTCATGGATGGCAGATGCTGGAGAAAGGCAGATA +TGTGAGCTTATATCAAACCCTAGGAGATTCAACTTTAAAACCTGGCTCTTTACTCACTGG +GCTTGAAGATTGCAGCCCAGTTATATTTTGCTGTTTCCTCAGCAGACATTTCTTCTCCCT +GGGCTTTGTGGCTGTTTACATTTCTGTGCTTAATTGATCCATCCTCTCAATATCAGAGAT +AAGTTGGAATTAGCACAGGTAGGAGCATTTCTACATGTTTCACAAGTACTTCAATGCAAT +GTGTATATCCATGTATTGCAGAAGGAAGAAAATACTTTGAGAACTGAGCAGTTAACATGA +ATAAAGGACATTAAATATTATAAACCACATAACATCATAAAAATATAATTAAACAGTTTT +TGAGCACTCAGCTACATGGAGTCTGATGCTTCTATGCTTCATATAATTCTGTGCATAAAT +TAGGCAACTAGATGTACAGACATACAGAAAACATCAATAACCAGACTCTAGAGCCAGGTC +CTATTTGAACCCATAATACAATAATAATAATAATAATAATAATAAAGTGAATTTGGTCCA +CCCATAAGAAATAAAAATAGTCAACACTTTAAACTACTCTGACTAAAACACTGAATTTGT +AGCTCTCACAAGATGGTGCTACCATTCTTTCTTTAAAGTATGTGCCATTTAGTTGAGTTC +TAAAGAAATAATCCTAATAATAATTACACTAGAGATAATACTGGTATAACTACTTTTTTC +TATAATAAAAAGAATTTCTGTATATTTTATTTTGTCCTATATTTACTTTTAGTTAACAAT +TTTAAGGAATAAGGATAAAAGAATGTCACCAAAATAAAATTTTGACATAGTCTAGAAACA +ACAGAAGTTAAGTTAAACGTTCTAAGTACACGATTAAATTCTACACGTTAATGAGCAGTC +GCTGCCATGCACTGTGAAAGGAGCTGTGCTCTGCCCTGGGTGGGGTACCGGGCAGGCGCT +CACGCCGTGCTTCCCTGTCATCAGATCAGGATGCAAGCTAATGCTAAAGAAAAATCCATC +CTGGAAATCTCTTATTCATGATTATATTTAGGATATCCACATATAAAGCTGAATCTTAAT +TAACCAGAACAAATCAGTGAAGAACCTCCAGGAACTCTGTTCTCCTCCCTCTTGTCTCCC +AGACACGTTAGATAATAGGAAGAAGTGAATTAAAAGAGTGCTTGTGAACATCAGGGAATG +TTCTGGGAGCCACAGCCATCTTAGCTACCATGCATTTATACACTTGCAGTCTCATTTATA +AAATCAAAAATGCATAATAAGGACGACAACAATGATAACAGCAATCGATGTGCATCTGGG +AAGAGCAGCCACCGCGAACTGCTCAGGCACACACATGTGCTCCTCTTACACCGCCCACTG +CAATGAGCCAGCTACTCCTATCCCACATCACAGAATTTGAAACTGAGCTTCAGAGATAAC +AAGTAATTTGTCCAAGGTCAGGAATGAAGCTTGTCTCCAGGTCATCCAAGACCCTCAACA +ACCTCATAAATATGAAATTGTGCTCAACAGACCAAACTGACATTTATCGGAGCATTTTAC +TTTTATGAGGCAAATGTTCAAGGGGGATTAATGTGGTGACCTGCCTCACTGGGTTTCCAG +ACTGTACAAATAACAGCATCTGATGCTATGGTTCTGGGTAATCCCTGATAACTGAATTGG +TTCTAAGCAGTTTCAGGAATATATTTTATGAGGAATAATTAGAGAAATAAATATATTATG +AACTAAGAAAGAGAAAGAAGGCGAGATCACACACCTGGTTTGGTCCCTGCCCTCACAATC +AGGTGTTGGTCTAATTTTCTCTGAATTGCAGATTCCAAATGAAATGAGGATAAAGCAGAG +TGAGAGAGGAGGGTAGAGGAGCAACGTGGGTGGTTTTCAGGTGCAGCTGAAGGGAAGGCC +ACCACTGAAGGTCTGAGGGGGCCGGGATCTCACATTTCTCCTTTACTGAGGCTAAGATGT +GTGTTGACTGTTCCTTGTGCCCAATTCCTCACCCAATTGACCACAAATGCCTCTGCCTCC +TGGGGAGGAGTACAAGAGAGTCAGGAGTTGAGCTGTTGTTGGAGAAACTCCATCCACATG +AAAATCACAAGAGTGAGGCCAGCAGATCCAGGAGCCTATCTGCTTTCTCAGATAACAATC +CACAAGCCAGTTAGTGCTGTGCCCTGTTAGTTTTTTTCTTTGAAAAACTCCAAATGACTT +AAAGTTCCTCTTTAATGTAAATATTAGAGATAATTTTCACAAGGAGAAGTTTAATGCCCA +CAAAGAATTCACCAATAAAAGGTGAGTCAAGTAATGATTCCTTCCATGAAGAAAAACCTT +CCTGGTTACCGGGAAGCAAACCCCACTGAGTTACTAAAAAGCTAGGCATTCACAGATGCC +TTTCCTTCTGCACAGCATATGCCTTTCAGCCTTATACTCATGTACTTAAAAAATCGGAAG +GATCTTTGAGGGAATTGGCCATTTCCTTTATAATATTCAAGTTTAGTTGAAGTAGGGGTT +ATTTTTCCCAAACAGGAAGCAGAATTAGATCACAGTCAGCATTGGTGACTGGCAGCTGCC +CTGAGGCCCATGATTAGAAAGGCTGGTCTGTGGATGTCCCTGTTTCACTTCCAGTCCACT +TTCTCATGGAGCCTGCATGAGGCAGACCCTGTGCAGCCAGCACCCCTGGCCTGACTGTTT +CAGGAAAAAAATCACAGCCTTGGGAAGGTCACAACTAGGAGAACACAGCCTTTGCTAAGC +ACCCTATGAGGCACAAGATAGCCCCTACAACAAAGTGTTATCCAGCCTAAATTGTGTGTA +GTGCCCAGGTTGAGAAACCCCATCCCAGACAACTATGGGATGGGTAAGAGGACGGGGAAG +AATGCTGACGCTGGAGGGTCCAAGCTTTTGATTATGAAACCATTCCTTCCAGAGTCCCTA +GAGGGAAGATCAGAAAATTGGACTGTGCATTTGCAAGCCTTGTCTCTCTCAGAGGCCCAA +GAACTACACAGCTGGACCTTCCAAAGGGCAAAGCCAAAAGATGGTGGGAGGAAAGTACAG +GTGATGTAGCTGATCATCACACCCAGCAGCCCCTCCGTGGGGCTGAGACAGATTCAGGAG +CTCGCACGTGGAGGACTCAGTGTCCTGCTTCATCAGGTTTTCAATTTAAGGCTCGGGCCC +TGGGGCCATGTAACTGTGACTTTTCTCTGCAGCGATGGTAAGCAAACATGAGGAAATCCT +TGGTAAGAGGTTAATGCCTTCACAGCTGCGTTTAAAAAAATTCCGTAACGTAAAGTGAGT +TTTATTTAAAAAGTGGACTGTAAATCTTCCCTTTTAATTTTTTCTTCAAGAACCTCTTTG +GAGAATGGGCTAAAGGAATATTAACTCAGTTGTAACTGAGTTACCATTTACCTTGTCCTG +TCCTCAAATACAAACACAGAAGCAACGGAGAAACCAACCATGGCAAGTGATGTTCCCTTT +GGGTCCCACAGCTGGTAAGTGAAAGTACGGGGGTTCGAACTGGAATCTCTGTCTCCACAG +CCCACTTAGAGTTTAATTTCTTATCAGGAAACGTTTTTCCTTGGTGCTGTTTATAGGAAG +TTTCTAATAGAGAAAGGAACTCTAGTTCCCAATGTCACATTACCAAGGCATTCTTTGGGG +GATCTGTGGCCTCAGCTCTTTTTCAGCCAGCTTCCCTCAGCTCTGTCTCTCTGTAGGGAT +CCCCTCCCTTCCCAAGCAAGTGCAGCCAGTCAGCTGACCTTGTCAAGTTTAGGAGCACTT +TAACAACCAGATACCTAAGTCTAAGTCTAATCTTGAGTCTTTAAAAGTAAGAGGCTGTGT +AAGATAAAAATCTAGGTGTTTACGCTGTCTTGGTGTCAACATTTATACCTTAACCACTTT +TGCTTCTACAGGATGTGTATCCAAAGGCCAAACTTTTCATGTCTCTTTAAATCAGCCTGT +AATGTGGGTGTGAACTTGATGTCTCTTTAACATGGCCTGTAACATGGGTGTGAACCACAA +AGGGTGAAACACATTTTTAAAACCTCTCAGAGCTTTCTCTGCATACCTAAGACCATGGCA +CAGCATCTTCTGTAGGTGAGCCCCCGACCATCGCACCTGCTCTCCATACAGGACTCTAGG +AGCAGATGCTCAACCCCCTCGGAGGAGAAACATCTGGGAAAAACACTGGAGTGGGCTCCC +AGAAGGGGAGGCCAGGGTGAAAAGAAAGGTCACCAACCCTAAATCCATCAGGAACATGCT +GACCTCTCTTCAGGGGATGCTGCTTAAGAGACCTTTTCAACATATTTTTATCTGCATGAT +ATAAATTTTTAAAATATGCTTGAGTACCTAATTTTTGGTATTTTATTTACATGAAATGTT +TAATTCTCCGACAGTTTTATATCCAGCAGCATATAGCTTTGTGACTCCAATGACGAAAGT +ATTCAATGTGAAAAAATAAACAGGCTATTTTATGATTGTTTAACTTTGCCCTCAATTTGT +GTACCACTCACATTTGCAAATAATTGCTCAATTCTCTTCAGGGAAACCTCTGAAGAATAT +TTAAGTAAGACAGATTGAAGGACCATTTTTACTATGGTAAATCTTAACAAGTTTTATAAA +GTAGTTTCCAGTAATAACAAAACATTTGAATGTGAAAAATAAAATTCTTAGAAATATAAA +ATTTATGGTGCTAAAACACAGAGAAAATGGAATAAGGATGAAATTGTAATTCAGAATTAG +CAAACTTTCTCATTTTATCTCCATTGTAAATTCAAAAGCTTCCAGACAGCAAATGTGGAG +GAGATCACATGCTCCTCAGATGATGCCATGGCTCCCGGGGCTCAGCAGCCCTGTCCCCAG +CACACACTCCCTACACAGATAACACTGACGGTTAGCTCCTATCCGGGGCTTAGCAGCGCT +GTCCCCAGCACACACTCCCTACACAGACAACACTGACTGTCAGCTTCCTATCACCCTCAT +TACCTTAAAGGCAAGTAAGATAACAAAAGCATAGCATTTTCTAAATGAAGTACTTCTCAA +AAGAATGTGAATATTCTATAAATTAAAGGGCTGAACACTTCCCAGAGATTTTCATAACCT +GTCAGATTAATTAGGAAGTTTGTGATCACAAAATGAATATGAATCATTTATAACATATAG +ATTTACTGATTTACCAACTCTCTCATGATAGCTGGAAAGTCCAGGATAGAGCTTATATTC +ATTTCTGTTACCTGCCAAAAAAGAGGAGAGTGGTGATTTTGAAAACTGATTAGTATATAT +CATACAAAATACACAAAATTGCCAGATCCTGCCCTTGCTGAGCAAATATTTTAAATCACT +AAGTTGATAGGATCATCATCATTTGATTGCGCTTTAAATCACAAGGTATACCTGAATAAA +GCCAGAAGATACATGAAGTATAAGGTAGATGATAAATACCTGACATCTGTATGACACAGA +AGTACACACACTATTCTCATTATAAATTCAGATGACAATTCTATTAGGTTCTTCTTCAAT +TGCATTGAAGGCAAAGAAACAGAAATCACTGATTCATGGAAGGATTTACACTGCATAAGA +GCCATTCACTAACTGCATCCACATTTCACACTGGATTCCCGTTCTGACGCTCTGGGGTGA +TGTAGTGTAGAAAGAGGCAGAACGGTCTGGGGGTTTGCTTTTCTTCTTCAACTGCAGAAA +AACTGATTCTAACAGTACAGAAGACGAAGAGCACACCTTGCACATCATGTTCAGCTTTAA +AAAGAACTTATCCAGGAGCTGGAGATCTGGAGATGGTGTCTCTTAAGTGGCCTGTGCCCA +CACCCCCTTTTGCAGTCTCTGCGTACTCCTAAAGACAGGCACACACCAGTGTGAAGGCCA +CTGGCCTAAGACATTTATGAAAGTCAGAATTTAGAAATAAAGTTTGGTGGGATGGGAAAA +GGATACAAATATCCTCTGAGAATCTATTTTTAAAAACTGACTAGAAATAGTTTTGAGCAA +GTGACGAGATATAAGACAAACAAAATATATGCAAATTAAGATTTCCTTCACTGTGAAAAT +TGGTACTTAAGTAGAAATAGAAAAGTGCATTCCATTCACCTTAGCAGATCAAAATCTCAA +AGTACTTGGGAACAAATTTAACACAAAAGGCACAGAAATTACAAAGTCTTATTGAAAGAC +ATAAAATCTCAACAAATGGAAAGCATGAAATGGTAAAATTATTATATCTCAAAGTAATAA +ATGTATACATGTAATGTTACCATAATTAGCATTGAAAAATTATAGAATGGATACAAGTAC +ATCATACTGTTTCAACTAGAATTGTATATTGGGGAGGAGGGGAAAATTAGGAAAATGAGC +TCAAATTATGTGAAGACTAAGTATCCAGTAAATGCAAAGATAAAAAAATCACAAGAAAAT +CTAGGAGACTATGAACATACTCTTGTGTAGGAGGTGGGAAGACCTTAATCATGACCAAAG +TATCCAAATCTATAAAAACTAAATGATAGACTTATTTTTAGATAAAATTTAAAACTTTCA +TGGAGTAAAATTATGAAAAACAAGATCAAAAGAAAAATGGTAAGTGTAGAAATATGCTGC +AATCCAAATGACCAACAAAACCTATAATATAGATAACATTTCCATAAATTGAGAAAGCAA +CAAATATCCCAATAGGAAAAATAGACCAATGAAATGAAGAGACTTTTCAGATAAGATTAA +ATCCAAAACACCAGCAATTTATATGAAGAGATGTTTACATTCACTAATAGGAATAAATAC +AATCCAATTAACAAGGAGATGTGACAAGCCTTGACTGGCAAAATCTTCTAGATGCTTCCG +CACTAATAGTGGTGGGGAAGGTATATGCTGAAGAATGTCATAATGGATGTAATAGTTGAA +AATGCACTTGGTGGGGAATGTAGATGGTGGAGAATGTATATAGTGAGGAATGCATACAGT +GGGGAAGATATATGGTTGAGAATGAAAATGGACAGTGGGGAATGTGTATAGTGGGAATGT +CTGGTGGGAAGCCTATATAATGAAGACTTGGGAATGTTATTGGGGAGTGTATATATGGTG +GGGAGTGTATATATGGTGGGGAGTGTACATATACTGGGGAGAATACATATACTGGGGAGT +ATATATGGTTAGGATTGCACATGGTCGGTAGTATACACGGTACAGAATATGGTGGGCAGC +ATAAATGGTGGATAATTCATATGGTGGAGAATGCATATGGTGGATAGTAACCATGGTGAA +AAATGCACATGGTGGGTGGTACACATGTTGGGGAATGCATATGGTGGGTAGCATACATGA +TGGAGAATGCATATGGTGTCTAGTGGGAAATGTGCATGGTAGGAAATGCCTATGGCGGGA +AGCAACTATAGTGGGGACTATTATGGTGGGAAGGTTATGGGGAGTGTATATATGGTGGGG +AGTATATATGGTTAGGATTGTACATGGTGGATGGTATACATGGTGGGGAATGCATGTGCT +GGTGAATGTTACGGTGGGGAAATGGTTGATGAGACTCTAAGTAGTAAAAACTTTTGAAAA +GTAATCTGCTAAATCTGTTAAAACTTTAAAAATATATTATTTGACCTATTATGTCCACTC +CTGGTAACTATCTCAAAAAAAATAAAAGTGCCAGTATATATAAATATTAATTTAGAAGTA +TATCAATTGTGACACTGTTTGGCATGGAAAAAAATCTGAAATAAAGTTAATATACATCAA +TAGGAGAGTGAATGAGTAAACTATATACATTTGTGCCATGGATACTGAATAATTATTAAA +AAGAAGCAAACAGAACTATACCAGTTGACTTAGGGATTTCTACGCGGAGTTGTTGAGCAA +AACAAACCAACAAATAACAAATAAATAAATAAATATAAAGAAGATATAGTAAAGCACGTA +TAAGATGATAGCATTTTTATGAGACAAAAATATTCTGGCCATGTTTATGTATATGTTTGT +ACATGCCATGTGTAGGACTACACAAGAATGGAGAAAACAACGTGAAAGTTCATAATTTAT +GTTGTGAACGTGGGTTTCCTGAAATCAGGGTAGAGGAAGGTATCTTGAAAGTGAAAACAT +AGGTGAAATGGGAAAAGGAAGCAACACAACAAAGGAAAAGAAAAAAAATACTGCCTTCAC +AGACCCTCCATATGAGCATACGTGCATTTCCATAAAATTATGTGTGTGTGTGTGTGTGTG +TAAGGATATGTAAATAAATTGAAAATACTTAGTTTTTAAATAAAGAACTTAAGAAAAGGT +CAGATTTAACATAAAACATTAAAAGTAGTCACTAGTTTTAAATTTTTAGTTTACTGAATT +AAAAACTGATATTCAAAACTTGAGAGATACAGCACATGAGAAATGATGGTATCGCATGGA +AAAACTGTAGTGGCCTAGCCACAAAGGATGAAGCTGAAAAGGTGGAGGGAGGAGGAGTGT +TCACGAGTGTGTCGAGTGAGGCTGAGGCTGCAGAAATGTGGCCAGGCTAACCTGTCCACC +GGCAGGGACACAGCTGTGGCTGTGCAAAATGGGGAGGGCACTGCCCATCTCCCCAAGAAA +GGGTTCGGGGAACACACGTGGTCACCGTGGGAAACAGATCCGCAAGCTGGCACAGGCAAA +GGGCCTGTTTTTAGAAAGCTCACACAAGGGGGTTATATGGCAGAAACAACCTTCAGAGCT +TTTCAATTATTAACGGAAAGGAATTTTTTGAGGTAAGGTCCACAGTCATTTTTAAATCCG +CACTGATAAGGACCTGATACTAAGAGGACTAGAATTTTTATAAATGAGAGGATTTCATAC +ATGCATATGCAGGTATCCATTCTCAGTGAGGACATTTTATATATTTTAAAACATACATAT +GGGTCAAATTCTATATAATCACTCAGATCTAAAATAAAAATAAATTCAGTGCTCATATCT +CATTAGTCACTGCAAATATGAGTTTCAGTAAATCAATCATCTGAACATGAATCAGCAGTG +GACCACGGCTTATCCCAGAAGAACAGGAGACAGACGCAGGGGCAGGAGGCAGGTTGGTAA +TGAGGAATAGGCCTGGTTCCTGAGCATCTTCCTGGGAGGGTTACATTTAGACCAGTCAAA +GGCACAGCCAAGAATCATATGAGGGACTTGGGCTCAAAACTGGGGAAAATGATTACAGAA +AATTAAGGAGGAGGCCGAGGATGCGCTTCCCGCCTTCTGCAGAGCTTTACTATTTACTCC +CCGCAAAACTTATATGCCTTCTCCCACTAACAGCAGTTATGTTTCTACATGTAATCTCTC +TCCTCTTGTTCTGAAAGTCCTCTAAAGGCAAGATCTACGTTAAAGTCACCTTTGTGCACC +CAAAGCCACAGCACAATGACTCTTGTATAACAGTCAATCATCACATGAAAGTCCCTACTT +CAATGTATTCCTATTTACTGGTAACCTCCATATACGAAAAACAGAAACACAAGTGATTCA +CAAAAATGAATGATAGAGAGAAAGATAAAGACCAAAACCTGGTGCTTTATAAATGTCATC +TAGTTTAAAAACCACCTTATGAGATCCTGAGCTCCAAAGAACATATGTCAAAACTGATAT +TCAGAATTATAAATATGAGTATGATAAGAAAAAAACAGGCTTATTTTGTTCTCATTTCAA +ATCAGAAGGATAACGGTTTTTGGAAGAAATGGCACAGAAAATAAATGAGAAAACCTTTGA +AGATAAATATCTTTGTAGATTTAAGAAAGTGTCTTATGGGCCGGGCACGGTGGCTCACGC +CTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCAGATCACGAGGTCAGGAGATCGAGA +CCATCCCGGCTAAAACGGTGAAACCCCGTCTCTACTAAAAATACAAAAAATTAGCCGGGC +GTAGTGGCGGGCGCCTGTAGTCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATGGCGTGA +ACCCGGGAGGCGGAGCTTGCAGTGAGCCGAGATCCCGCCACTGCACTCCAGCCTGGGCGA +CAGAGCGAGACTCCGTCTCAAAAAAAAAAAAAAAAAAAAAGAAAGTGTCTTATGAATAGA +AAGAGAAGTTTTCATAAATTATAGCAATGACAATTTGTCTCATGTATTTAGAAGAGGCTG +AGCACTTATTTTACTCTTAAATATGTTAGTTCTTCTATTTAACTCTAAAGTTTAACAATG +TATCTTGATTTCTTAATGATAACATTTAATAATTACTTAATTACAACTGTATTTGAATTG +CAACAAAAATATTTACTTTGAGAGCCAGAGTTCAGCTGGACTGGTGCAGATGACTGCTGT +GGTCTTGACAATGGCTTTGGAGGTAATTCTTTAGCCTGGGAGAAACAAAAAGATAAATAC +ACATAATTTTAAAATCTTGTTTTTACTTAGGCACATATAACTCTTTTCTAATGAGGTTAT +GTAGCAAACTTTTATCATGTGTGCTTATTAATGTGGCACTCTCAAAGCTCACATGCACCC +CTCTGGACTCTATGTAATTGAACTGGATGACAAGACTCAGATGTGGACAGGGTGTGCTCT +TCTCATGCCTGGAAGCTAACCTCCCCCAGGCACCTCTGACCACCTGTGCAAGGTCTTAGG +GAGCTGCAGGGACGGTGGTGTAGTAATTGGTTTAGCAAGCAACTGGCAGAGGCAGTGACA +GACAAACTCTAGGCTTCAGTTTTTATTCCATGAAACAGGCATCATACCAACTCTGAAAGG +TGCTGTGGAACATCATGAACAATGCACACAAATCCCTCGGTGCCCCAAGGCCTGACATAC +AAAGGCGTCAGTATCTGCAACTATTATTCATATATTATTATTGAGATAAGGTCTTACTCT +GTTGCCTAGGCTGAGTGCAATGGCATGATCTTGGCTCAGTGCAACCTCATGGGCTCAAGC +GATCCTCCTGTTTCAGCCTCCTGAGTAGCTGAGATTATGGGCACACGCCACCATGCCCAG +CTAATGTTTCTATTTTTATGGTAGAGAGGGGGTTTTGCCATGTTGGCCAGGCTGGTCTGA +AACTCCTGATCTCAAGTGCTCCACCTGCCTCAGCCTCCCACATATTATTTGTATTATTGA +TACAACAAAGTTCCATCCTTGGAGAAATGCAATCACAGAGGACAAATTATGTTTTTCCCT +GAAATCTGTACAGAGGAAATGTCAAGGTAGCATGACCTTTTCACAAGAATGTGAAGTCAG +TGAAACTACGAAGGAGGCTTAGTAGGTTCTTAGGAACCTGATATCAGGGACAGAATGTTC +TACAGAAAGAGATTTTCTGAGAATACTGAGTGAAACATAAAACCAAACGGTACAGAAGAC +TTCCTCTGCTCCCTTGCTGCTTTTCTTGCATTGATTCGTTGTCCTTCATTTTCATACTTT +TCAGTAAAGGAATCAAGAATTTCATAAAGATCTTCGGCTTGAGCAGGCCGCGGTGTATCT +CCAAATAAAATGTCATAAGCTCGGATATCTTGACAATAAAATCTAATGGGAAATATAAAA +TTAAAAACATTTTAATATACACAAATCTTTTCTAGAGTTAAACATAGCATGTGCGCACAC +ACGGTGTGTATATATAATCATTCATACATAGCACTTCATATACACTACTTTTTAAACACT +AACTTTAAGCAATATCCCATGTTCAAGTCTTAAATGTACCCCAAAGTTCACTTCTACAGG +CAACTACCATAAATATCCTTATATGTATCCTTTCTTTATTAATATAAAAAGCACATCCAC +ATTATCATGGAAATACTTATACTTGCCCATATATATACATACACATATTCATATATAAAC +ACATATAAATATACACACAAGCACATACATTTTTATAGGTTTTTACTTTTTAAATTTCTT +TAAAAAATGGTACCTATAACTGTGGCTTTGTAATTTCCTTAAAATATTTATTTTTATCAA +GATTAAATAAACATTTGCCTTACATGCTTGGAGGTCCTGCCATTCATTAAGCAACATATT +TGTTTTAGTTTATCCAGGGTTTAGTTGAACTTTAGTGGGAAGGCCTGCCAACGGGCTCGA +ACCAGAAGTTTCTAAAAGCATTCTTTTGTTAACTGTTCTCAAATTAATAAAGCCAGGAGT +TAACACATCACTTTTGATTTTATAAGATGAATAGTTCTGAAAACCTTATTTTTCCCCATC +CCTCCTATTTTCTACCTCTTGTGGTTTATATTTAGCTTTATTAAATAGTGCTGTTCAGTT +CCTGAATGACTCGGTGGGGTAAACACTGGATGCTTTGTCTCGGATAGTGGCGGGTCTGTC +TGCCACGCGTGGCGAATTTGAATGGCCAATGCCAGCAGTGCCAGCCGATCAAGCTGGCAA +TGATGGAACTTCTGCAGGTTCTGGAAGAAGTCCTGCTGTCAGTCTTAGCTCTTTATCTCT +TTCTGGGCCTTTACACATATTTTAGTGGCAATTTGTAAGAGCCACTTAATTTGCATCTTT +GGGAAAAATCAGCCAGATGCCAATTTAAAGTAGAAGTTTCCCTTTACCTTTTAGGATACT +TCCAGATTCTTTTTTTTTTTTTAAATCAAACTGTATTTTAAATTGCTCTCTATTTGACAT +GAGAAAAGACAAAGGTGGAGTGTAGAACAGGAAACCTCACAACAAGGAATACTGACTGAC +ACATGAGTTGTAACTGGTGTGCCTTCCACAAACATCTGAAAATCACTGAAATCGGTGCAT +CCAACTAAGAGTATTACTAACTTATGTTTAAGTTTCTTTTTTTTTTAATATACTTTAAGT +TCTGGGGTACATGTGCACAATGTGCAGGTTTGTTGCATAGGTATACATATGCCATGTTGG +TGTGCTGCACCCATCAACTCGTCATCTACATTAGGTATTTCTCCTAATATTATCCTTCCC +CCAGCCCCCAACCCCCTGAAAGGCCCCAGTGTGTGATGTTCCCCTCCCTGTGTCCAAGTG +TTCTCATTGTTCAATTCCCACCTGTGAATGAGAACATGTGGTGTTTGGTTTTCTGTCCTT +GTGATAGTTTGCTGAGAATGATGGTTTCCAGCTATCTTAAAATGCGAAGTGGAAAAAACA +GCATTTACAACTGAATATATATGGTGATTATCATCATATATGGCAAAACAAAAAAAATTA +TGCTTAGGAAAATGTTGGAAGGCAGTAAAGCAAAATGTGAATTGTGTTAGTCTTTTAAAG +GGATCGAGTTTTTTTTATTTCTTTTTCATGTGTCTTCTGCATTTTCTACGAGCATATATT +ATTTGTATATTTAATTTTTAAATGTAAGATACACACTTAAAACCACATGTTGTAAAAAGA +ATATATAAATGTACTCTGCAAATTATATCAACTTTTGAAGTACTATTTTCTCATCACACT +TTCAATTAAAATCACTTTAACTTGAACTGACTTTCTATTAGTTTCTTTCCTTTCAATCAA +ACAGCTCCCTTCTAAAGACACGCCTGCAAAGAGTCCCCTTGACTTGCAGTACGTGAAGAC +GGCAGCGGAGCTTCTCAGGGCCACGTTTCCTTCCAAGTTCCTGCAAAGCACAAGATTTTG +CATCACAAAGCTGTGAGCAGCTCCAAGCCGAGGATCACTATTTAAATAGCACTCCTTCTA +GCTCAAATGAATTATTTTGTTCTGTACCTTCTTCAGCTGTTTCTATGTTTTACTTACTGT +AGGCCTAAATTAGATGTTTTAATGTGGCCTAGAGGAAAAACAGGCCGGGGGAAGAACATA +CATGAAATTATTACAGAAGGCTCTGGTAACATAGAACTGTGTTGAAAAAGAATACAGTGC +AGCATGTGTAAATATATTTTAAAAATTTGTAAATCTGACATTTTCCAACCGGATCTTCCT +CTCTTAAAACTGGGAAATACATCTCAAGAGTGCTAAAGAATTTGGATTATTTTTGCATTG +AGTATTTTCATGGAACCAAGAAACATTTTTAGATGATTTTACTGTGTAACTTCTATAAAT +AGTGTGGGTATAAAATATCTCTACATTGCACAATTAATCCAAGACTAGCATTTCATTAAT +AGAGAAGAAAAATACACTTTAAGTACTGTAAACACGGCTCAAAAAAAACACATCCATATC +CAATTTTTATGATTTACTTTGAAAAAAGCTCTTTCTTTCCTAATCGAAGCTTAACTTTAT +CATAAAATCTGACTTGTGTTTGGCTCTCTCAAAGCTTAAGGTGGATTTTATGTTCAAGTC +TGACAGATACAATGGCCTATGCTTCCAAAACATTTCATTATTTCTTGTGTGTTCTGGTTT +CAGATTTTCTAGCTTATCTCACTGGCTGTGTTTTGTGAATTTCCTATTTGTGATGACCTC +AAATCTTTCGGGCATGTATAAATCTGGGGATGTACAAATCTGTTCATTTTAATTCAAGTT +TCCTATTAATGCAAAATAAAATATGCAGTTGTTAAACCTTTACTGTCTAACATCTATTTA +AAGAACTCACCTTCCCAAGGGCCCAACCGCCACAGTCAAGTTCCCTCCGAGGGTCAGATT +TCCGCCTTTTGCAAAAGCTTCTACAGCACGGTCATAATTCAGAATTATCACCAAGTCTGA +TACCTAAAGTGTAGAAACCCATGGATTTAAAAATCGTTAAGACTAAATATCATTTAAAAT +TCATCTTGACTAACACTCAACTACACCATATGCACTGTAGCAAAACATCAATAGAGACAG +GAAAGAACGTGAGACAAGAGCCATATTTTTATTTTGAGCTGATGAATTATGAAGCCAATA +TTGCCACAGGTAATTACAACAAACCTCAGCGAGCATTTACTGTGCACCATGTGTATACTA +TGAGGTTTACCTGCATCATGTCCTTCAATCTTCCACACAACCTGGTCATGTAGGTGGTGA +TCCTAAGGTTTAGTGGGGTTAGGTAAACCGTCAGTGCTAACAAGTCAAACAAAGGTTGTT +GGAAGGGATCCAACATGCTCTCTGATCTCATCAGACTAAACTTTGTAAAAGCCAAGCCCG +AAGAGCACAGCACCAGGGACGATGGTGCTGAAGGTCCTGAGAGCCTTTCTACACTCTCCT +CCTGGCCAGGGGTGTGCTCCTTACCAGGAAGCTGTGAACCTGGGCCACTTCACTATAGGT +CACAGAAGCTCAACACACCAGAAAGCAAAGCAGTTTCCATTAGGAATGCCTATTTCCATG +ACTTAATTTTTCTTTTTTTTTCCTTGAGAAAGAGTTTCACTCTTGTTGCCTAGGCTGGAG +TGCAGTGGCGTGATCTGAGCTCACTGCAACCTCCGCCTCCCGGGTTCAAGTGATTCTCCT +GTCTCAGCCTCCTGAGTAGCTGGGATTACAGGCACGTCACCATGTCCGGCTAATTTTTTG +TATTTTTAGTAGAGATGGGGTTTCGCCATGTTGGCCAGGCTAGTTTTGAACTCCTGACCT +CAGGTGATCCACCCACCTCGGCCTCCCAAAGTGCTGGATTACAGGCGTGAGCCACTGAGC +CCAGCTGACTTAATTTTTCTCTAAATAAAAGAAGAAACTACAATGAGATTCAACTGAATG +CTCAAGGCAGGTCAACACAGTGAAAGCATTTGTTACTCAAATTAATCACTGCAATGTGGA +AGTCCAAAGTTAGAACTGAAAAATAATATGACCCATCAAATGAGAGGCAGCATGGGTCAG +GGGAGGCAGCATGGGCCAGGGGAGGCAGCAGCATGGGCCAGGGGAGGCAGCATGGGCCAG +GGGAGGCAGCATGGGTCAGGGGAGGCAGCATGGGCCAGGGGAGGCAACAGCATGGGCCAG +GGGAGGCAGCAGCACGGGCCAGGGGAGGCAGCATGGGCCAGGGGAGGCAGCATGGGTCAG +GGGAGGCAGCATGGGCCAGGGGAGGCAACAGCATGGGCCAGGGGAGGCAGCAGCACGGGC +CAGGGGAGGCAGCATGGGCCAGGGGAGGCAGCATGGGTCAGGGGAGGCAGCAGCATGGGC +CAGGGGAGGCAGCAGCACGGGCCAGGGGAGGCAGCATGGGCCAGGGGAGGCAGCAGCATG +GGCCAGGGGAGGCAGCATGGGTCAGGGGAGGCAGCAGCATGGGTCAGGGGAGGCAGCAGC +ATGGGTCAGGGGAGGCAGCATGGGCCAGGGGAGGCAGCATGGGCCAGGGGAGGCAGCATG +GGCCAGGGGAGGCAGCAGCACGGGCCAGGGGAGGCAGCAGCATGGGTCAGGGGAGGCAGC +AGCATGGGTCAGGGGAGGCAGCATGGGCCAGGGGAGGCAGCAGCACGGGCCAGGGGAGGC +AGCAGCATGGGTCAGGGGAGGCAGCAGCATGGGTCAGGGGAGGCAGCATGGGCCAGGGGA +GGCAGCATGGGCCAGGGGAGGCAGCATGGGTCAGGGGAGGCAGCAGCATGGGCCAGGGGA +GGCAGCATGGGCCAGGGGAGGCAGCATGGGTCAGGGGAGGCAGCAGCATGGGCCAGGGGA +GGCAGCAGCATGGGCCAGGGGAGGCAGCATGGGCCAGGGGAGGCAGCAGCACGGGCCAGG +GGAGGCAGCAGCATGGGTCAGGGGAGGCAGCAGCATGGGCCAGGGGAGGCAGCAGCATGG +GCCAGGGGAGGCAGCATGGGCCAGGGCACCCCTGGGTGTGAAGAACCAATGTCCATCCCA +GCTCCGCTTCTCGAGAGCTGTGGACTTTGGGGTCTTTTAACCAGTCTTTGTGTCTCTGAC +TGTTCTGTGTTTAAAATTTGCTTACTAGGACCTACACCTCATGGAACTACTGTGAGAATC +AGATATAGGCGTCAAGTGTACCTGGGAAGTTGAAACAGTGCTGGCATGGGGCTAAGAATT +TGGGCTCAAAATTAAAAATAGTTAGGTGGGAACTCCATTACTCCCTTTTGCATGCTGTGC +GACCTTGGGCAAATCACTGAGCTGCTGAAAGCTGCAATTTCCTTCTCTGGAAAATGGGTG +TAATAATAGTGGCACACATTCAAGGCTGTTTACGGATGAATTGAAATCAGTTCAATAAAA +CATGCAAAGGTCAAGCAGACTCGTGCTTAAAATATGCCTTCATTATACAGTTATTCACAT +TTTTTAATCAAATCAATGCTCTCAAGTCAACATTTTTATATGAGTGACAGAAAAATCCTG +TTATAACCAAATGAGATTATACTTGAAAGGCCCTAAGAGAGTTCCTGATGCAAGTATGTT +CTTAATAATGTTCAATTTGAATCATTTTATGAAATAAAATACACTTCAGATCTGTAGGTC +AAACTAAATCTACCAGAGAGCTGACCCACACAAGATGCTTCAGCTTGACGCTTGCCAACT +GTTCATTTTATTTTACATATAGACAATTTCTGAGGGTTATGGTGCTGAATGGCAGATAAT +TATTTAGCTTTTCTTATGCAAAGTTAAGCATTTTCACCAGTGATTGTATAACCTGTATCT +TGTATGTATTTTTAGATAACAAATTTGCCTTCCATAATGCTTCCCACATTTCCCACTCGG +AAAATACAAAGTACTACCCATGACCTTGTAGCTACACTGGTTCTTATGTTCCGCTTCTGC +TTGGTACATCGTGGTACAGTTAAGTAAGGCCAAGCTATGAGAGGCAGCTGAAGGAAAAAC +AAAGTCTTTTGATTTTTTTTGGTCTGATCTCTCTTTAGTTCTTTTGAAATAAGAATAAGA +GAATATTGTGTTTTTTGGTGACACTACCAATTAGCCCGAGAACCAGGTCAAAAGCTCTGC +AGACAGCTTGGCGAGCATGTGAGCAGCAATGGCCCTCAGTTTATTTCCACAGCTTAGAAG +AAGGAGCAAGACAGATTTCCTGCAGGAATCTGGAGGAGCTGAACAACACATTGGGACGGC +ACTCTCAGAAAACCCTGTAAGCATTTGATAAGACTTCTTTAGAAGTCTGCATTAAAACTC +AACTACATAACAGTCTGATCGAAGAAATAAGACTTGTGTTTTATTTATAAGATCAGTAGG +GTGAGTATGGTTCACAATAATCTATTGACTATTTCAAAATAGCTAGAAGAGAACTTGAAT +GCTTCCAGCCTAAAGAAATGACAAATATTTAAGGTGACAGATACCCCAATCAGACTGATT +TGATCTTTACAAATTGTATGCATGTATTAAATTATTACAAGTACCAGGAAAATATGTAGT +CCACTATAAATCAAAAAAAAAATTAAAAAATAAAACTGAATAACTCAGATGCAAGTGTTT +CAATTAAATAAATTCTTAAACATTAGAATGTGAAAAACCACAGCTGCCATGCAGGGGAAG +CTGCGGGAGAGAAATGTCCCTCTTCTCTGCGACTGAATTTCCTGAAAGCAGCTGCTGAGA +GGGTACCACCCCATCTCCCTCTTGTGTGGTCAGCCTGCTTCACACCCACACAGCTGAGTC +CCGGGCTGTTGTCCTGTCAGAGCATCACCCCCTTCTGGATGATTGACTGCTGTCAGCCTT +CAAGCCCCACATCTGGACAACCCGCTAAGAAAGCTGGGCTTCCTCCTCCACCCTGCCGTT +CTCTCACGCCACTCTTGGGCTGGCCTTGGAGCCTGCCCCAATCTCCCTAAAAGCCTCACT +ACATGGGGAATAAACCTTTTCCTCCCTCCTTGTGTGTGTGTGTGTGTGTGTGTGTGTGTG +TGTGTGTGTGTGTGGCATGGCCAGTCTCAATATGTAAACCAAGCTTAAGTGGAGCGTCCT +TCCAGCAACAACACCCCCTCCATTCCTCAGACCAACAGATCTTTTCCTTACATCCCATTC +TTAGGGGGCTTAGAAACTGGACTCTGATCTCTAACAATAATTTATCCTCAACTTAAACCC +AAATACCTTCCTCTTCAGTAAAGTGAAAGGGCCCATGTAAATTCTCCCTGGAAAAAGCAG +TCGTTTTTGTTTTTTCAAATTCCAATCTTGAGTAAAAGCCAGACTGCTCTGGCTTGATGA +CCCAGTGTGAGCTCTAGCTCTGGAAACACAGCAAAGGACTGTACATGTCCAAAGCCAAGC +CAGCAGCAGGACTTTCTGAGCTTTGGGCTTTGCTACAACTGTCATCCAAAAAGAAACCGT +TAGTGGTATTTAAAGCAAATGTAGCATTGTCTTTCCTCAGACCACTGACTTTCACGACTT +CACTTCTCACAATCTCAACTCTCTTTACTAATCTCTCTCTCTTTACCACAAAAACTTCCC +CCTCCCCCAAATTAATCCCTAATCCAGATACACGTATTCAGTCACTAATTTAGACAATTA +TTCAGTACCTCTGATGTTCCAAGAACCAGGGAACTCTCCACCCTGTAGAATCTGGGAGTC +TAAAGGTTGAGATTGTCGAACATAAATTAACCCCACGCCGGCCTTCTGGCTAAGCTTAGG +GTCACTTACACTTATGCCCCTGGAAGAATGAGTCTGACATTCACTCTCCAGTGAAACCAC +AGCACGATGCAATAAGCTATCCAGGAGCAGCCTCAGACAGCAGTGGCTGTTAAGCAGCAT +CCTTTGCACAACTAGACCTTGTTAGTTAAGAGAACTGACCTTAAGAACAGGCCATTAATG +AACACACAATTAAGACTGCAATCTTTTTCCACCAGGATTCTCTAGGAGAATTAAGCACGA +ATGTCCTAAGGCATCCATTGCAACTAATAGGTTAGCATCTCCCCAGATATTCTAGAATAA +TAGTACAAATAATTAAGAAGGTGGTACTCCAATCCCTTTCTGTGTTTGGAAGGTCAGATG +AAGAACCTGGAGCAAATGTAACATTTTTGCAGCACTGGATACACCACGTGGAAGGTACGG +GAGATGTCCGGAGAAAAACTGAGACTGACCCAGGCAAAAAACAATGCGCCACAACTTTAG +CCCAGAACAGGCAAGCTTTGTTGCCAGTCACAAATATCAGAAGTGAAAGGGGGTATTTAA +GGACCATTTTATTCAACTTAAAAATTTTTTATTTTACAGATTTGATTCAGGAAGATTAAG +TACTTTGTTCACTGTTCTATAACTAACAAAAGAAGAGCTAAAACTTAACAATTACAGTTG +AATCTCCATCCCACTGTAGAATGTATCTACAAATCAGAATGACACTGCAGTGGTGGCATA +AAGAGGCCACAGACCCTCTCCACAGCAAAATAACCGTAACTGGTAAAAATTATTTTAAAA +ATTAACACTTCTGGAAATTGTCCTAAGGGCATATGGCAAGTGAAGAAAATGAAGACACAT +TGATTCAATGAACACTATTAAATATTGGTAAGGAAGAGAGAGTTGGTGACATTTGAGCTA +TAACCTGTGCCCCGCTGCAGGTCAGCCTGATGGAAGCTCCTCTTGGGGAAGGGGGTTTGC +AAGAACACAGACTTCCTTCCCCCAGCCCCTGGTCAGGGCTGCAGTATATCCACAGGAGAG +GCTTCTGCCAGCATTTCTCTTCCCACAGCTCCTTGTACAGAAGCTCCATTCCAGGCAAGA +GCAGCTGAGAGGTCTGGAGCTTCCTTCCTCCACCCAGAACCCATGTGTAAGTGAAGGCTC +CAGCCTAGCACAACAGTCCAGGAGCACCAGGACCCCACTCACTCTTGCCCCAGTTCACCT +GTGGGGCAAAAGCTCCACCCTGACAGAGGCAAGCCAAGCTACTACACCACCCAAGGCTGC +AGGGATGTCACTCCAAGAGAAGGGAGCCACTGCCCCAGCCTCCAGCTCTGGAGCAACGGC +ACAGAGATCTTGGGCAGACAGAGAGACAGGCTGCAAGAGCAGAGAGCTCCAAAGCTCTCC +CCAAGGGAAGTGAAAGCTTTTGGAACACAGGGTGGGGAAGTTCAAAGGTGCTGTCAAAAA +TGATGCTTTTGGTGATAAACAGGTAAGATGAGGTATTTAGCTCCATGACAGCAACAAGCT +AAACCATTGGTGGTCTAGAAAATTATCAGGGAGAACCAGGGACAGAGATAGCTAAGAAGA +GCCCTCCTGAAATAGAAATGAGCCTCAAAGACTACCTGTGCACAGGAGCACAATTTTAAC +TGGATCAAACTGTGGAGCAATTTATGTCCCCAGGGCATTGTTGGAAACAATGGAGCAATC +AGCAGGCAATTAGTGGAGGCTAACAACAGTGTGTAATACCAATGGAGACAAACAGCTTAA +CAGACAGGTCACGGACAGGGACAGTCAGAACACCTGTCATCTCAGGAAAACTATATGCAT +GCCCATAGACAACATTGGAGGCTTCACAGTAGTGGGGCACAGAATTCATTCAAACAGTCC +AGCCATATCTCTAAACAAACAGCAAGCAAACAATAAGAGGCTCCTAGGGGGAGAGGTTGA +GCACCCAGAGTTGATACAATATAATATCTAAAATTTCTGATTCTCAACCAAAAATAATAA +GACAAAGAAGTGGGAGAGTGTGACCCATACATAGAAAAAAAATTTAAAAAGGAAGCAGAC +GAGAATGACTGCTGTTCAGATGGTCCAGCTATCAGATTTAGCAGACAAAGACTTTAAAAC +AGCTGTCATAAATATGTTCAAAGAATTAAAGAAAACTATGGTTAAGAAGTAGAAAAACGT +ACAATGAGAATATCTTATTGAATAGAGAATATTGATAAAAACATAAAATTATATAAAAGA +ACCAAATGGAAATTCTGGAGGTAAAAAGTACATTAAGCAACATGAACAATTTACTAGAGA +AGTTTAACGGTAGATCTGAGCACGCAAAATAAAGAACTGGTAAATTTGAATAATAGAAAG +TCTTAAAAACTAAGAGAAAGAGAATGAAGAAAAATTGACAGAAACACAAGAAACCTGGGA +CACCATTAGGTGCACCAACATATGTGTGATGTAAGTACTAGAAGGCAAGGAAAAAGAGAA +AGAAGCAGAAAATTTTCTCAAAGAAATAATGGCTGAAAATTCTCAATCTGATGAAAAACA +TGGATCTACACTCAAGAAGCTCAACAAATTCTGAGTAGAATAAATGTAAAAAGATAACAC +TCTGGATAGATAATTGTAAAAAATCTTAAAATGCAAGAGAAAATCTGGAAAGGAGCAAGA +GAAAAATGACTCATCACATAAAAGGAACCCCAATTAGAATAATAGATAGATTTCTCTTCA +AAAACAGTAGACTTCAGAAAACAGTAGGATGACAAAATGCTGAAAGAAAGAACTGGTCAA +CTTAGAATCTTATAATCAGCAAAAGTATATTTCAAAAATGAAGGGGATATGAAGACATTC +CCAGATTAAAAATTTTTTTTTAAGTTGAGAGAATTTGTTGCTAGTAGAACCATTTTACAA +GAAATATTATAAATTCTAAACAAAGTCCTTCAGGCTGAAAGCAAGTGACTCTAGAGAGTA +ATTTAAATCCACACTTTAAAAAATCACCAGTAAAGATAATTATCTAACCATAAATAATAG +TATAAATGCATAGTTCTTCTCTTTTCTCTTAATTGGTTTAAAAATAAATTTTTTCTATAT +TTTAAGTCTGTAACTATAGAAATATTATATACTAGACAATAACCGTACAAAAGAGTCAGG +TGGGAGCAAAGTTGTCTTGGAGTAAGGAAATGACACCAGATGGTAACCTGAATGAACAGA +AACAATGGAACAGAACAAAAAATGGGAAATAAAAAAGGTTAATATAGCAAGTTCAATGAG +TAAATACTTGCTCTCAATTATTCTCTGAGTTTCTCTAAAAGACATAAAATTATATACATT +ATTAACTATAATCATGAATTGCTGAGTGTGTATCATATATAGATTTAATATGTATAACAG +TAATAGCACAAAAAAGGAGAAAAAAAACTAGAACCATATGAGAGTAATGTTTTTGTATCT +TATTAAATCAAGTTCCCATAAATTAGAAATAGTTAAGACATATTGTAAGCTCTGGAACAA +CCATTAAGAAAATGACTCAAAAATAGAGTTAAAAAATCATAAAAGGAATCAAAATGCCAT +AGTACAAAATGTTCACTTAATTGAAAACAGTAAAGTGGAAACAGAGGGACAAAAACGGCA +TGAGATATAGAAAAAAGTAAAATGGCTGATATAAATCCAATGATATCAATAATCTATTAA +ATGTGAATGAATTAAACAACCAAATAAAAAGGCAGAGATTATTAGCATGGATAAAACAAC +AATAACAACAACAACAACAACATCCAATTATATGCTCCATAGGAGACACGCTTTAGATTC +AAAGTTACCATTAGATTGACAGTAAAAGGATGGAGAAAGATGTGTCATGCAGATGGCAAC +CTAAGAAAGCTGGAGTGGCACTCTTTATATCAAACAACAAAAAATGTAATTAGGATTAAA +CAGGGACATATTATAATGATAAAATGGTCAATCAACCAAAGAGATATAACAATTATAAAC +ATAGTAATACACATATATTTATACAAGCACATAATATCGGAGACCCAAATACATGAATCA +AAAACTGACAATCTAGAAGGAAGACATAGACAATTTAACAAAAATAGCTCGATGTGTCAA +TAACCCACTTTTAATAATGAAGAGAACAATTAGTCATAAGATTATCAAGGATATGGAACA +ACTAAACAACCATGTAAACCAACTAGACCCAATGGACTCCTGGAGAACACTTTACCCAAT +AACACAGAACACACATTCTTCTCCAGCACACATGGAACATTGTACAGGACAAAAGTCTAT +ATTTGAGGCCATAAAAGAAGCCTTAACCCATTTAAAAGGACTGAAATTATACAAAATGTT +TTCTTTGACCCCAATGGAATGAAATTTGAAATCAAGGACAAGATAAATTTGGGAAATTTA +TAAATATGTGGACATTAAGCAACACACTCTTAAATAACAAATGGCTCAAAGAAGAAATCA +CATGAGAAATTAGATAATATTTTGAGATTAAGGAAAATGAAGACACAACATACCCACACT +TATGGAAGGCAGCCAGGGCAATGCTCAGAGGGAATATGTAGCTGTAAATGTGTCTATTAA +AAAAAAAACAGACCTCGAGTCGGTAACCTGAACTACCTATCAACATGGACGAAGAAGAGT +TTAACTAAACTTTAAGCAACAGCCTTGCTTGGACCTTTCCCCTTCTTTCCCTTAGTACCT +TAAGTTTCTTCCCCGGAAGAACATTTGCTCAGTATATCACATGCACTTGAACTGGTATCA +GGCTCCGCTTCTAGTGAACCATATCTGACAACCACACACTAGCTGTGTGATCTTAGGTAA +GACACTAATGTCTCTGTATATTGAAAATAATGTGTGTTTTGCCTACCTTGTATAGTGCCC +TAAAAACAGTGGCTTGTTATTCAGAAGAATGTTACAGTGAGGTGGGCTTTACCACCCAAG +CACCTGTGAAACCAAGAACAAGTAACTTTCCTGAACCTTTCTTTTTTCCCTATTGAGGGA +TGTGCAGACAAGACAGACTACAGGGAACTCTGTCTTTCGAATAACATGCTGCCTGGATGT +GGGAGCAGACGCTTCCCAATCTGCCCCTCTCTGGCTGCCTCCTACTGGAGAATTCTCCTG +GCTTAGCTATTTTACGGATAAAATGAGAGCGATGACAACCACCTTCCATGGCTATGAAAA +TGATTCCATAATAGCATGTGTACAAGTTTTGTAAAAAAAAAAAATGGCCTGGAGCGGTGG +CTCACGCCTTTAATCCCAGCACTTTGGGAGGCCGAGGCAGGCGGATCACGAGGTCAGGAG +ATCGAGACTATCCTGGCTGACACAGTGAAACCCCATCTCTACTAAAAATACAAAAAATTA +GCCGAGCATGGTGGCGGGCGCCTGTAGTCCCAGCTACTTAGGAGGCTGAGGCAGGAGAAT +CACTTGAACCCAGGAGGCAGAGGTTGCAGTGAGCTGAGATTGCTCCACTGCACTCCAGCC +TGGGCGACAGAGCAAGACTCTGCCTCAAAAGAAAGAAAGAAAGAAAGAAAGAAAAGAAAA +AGAAAGAAAGAACGAAAGAAAGAAAAGAAAAGAAAAGAAAAAGAAAGAAAGAAAGGCAGA +TAGTTAAATTATTCAACAAATATTGGATAGTACTAACCGATTACGTGTGTGCCATCTATG +TGCTTGAAAGGAAAACCCTGTGTGGTTACAGGTCCTGTCATTGTCCCATTTTACAGAAAA +GGAAGCATTCATGGGTGTCTCGTCAGTCTCTGTGGACGTAGGTGTGAAGTTTGAGAAAGT +CTCGGCCTTCCCGGTACTCACAGTGCACTTGAGGGCTGGTCCTTACTATTTGTGGCTGCT +AGGACATGGTAGGGGCAAGTTCCCAGAGAAGCCAGGTCCAAAGGGGATGCTCAGCTCAGC +CAGTGACCTGAGTCAGAAGTGCCCTCAGAGGTTGGTCCCTTCAGGAAGGACGTGTCTACC +CTCCAGCCCCTCCGTGGTCTCAGTGGGCACCAGATCTGCTGTGATGAGAACAGCCTGAGG +GAACCACTCTGGATACCCCATGCTCCCGTTCTGACTCCCTCCCTCATTAAGACAGCAGGC +GGGAGTGCTCTGTTAGGATGGAGGCTCAGACAGAATCAGAGAGTGCTTCATGGAGAGCAA +ACAGTGCTTTCTGTTAACATTGAAAAATAGCCGACTGCTGTGACATCACTGCACACTCAC +AATTACACGCAGAGACTTATCTGTGGGGCTCTGAGAAGCAAAGTCAGATCATGGTTAAGA +AGTTTAAAACTCATGTCTCCAATCCCTAGGAGATGCTTCTTATCTCTGTTTGAAATTGAC +ATTTAAAAGTTAATAGTTATGTTATTTAAATGAAATTCCATAGTTAATTTCCATACTGTC +ATGAAGACAGGCTTTGCAATAAAAAGTTTCTGTAAATGGCAAGCCTAAATAAGCTGCAAA +GATGAAGAAGATATTAAAAATAAAATTATATTTTGTGTCATTTCAAGGGCTTTTACTGTA +TAAATCCATATTTAATCATCAATATAAGCCCAGAGACTCATATAAGGCTATCTTTAACTG +TGTTTTGCAGATGTAGAAGCTGAGGTGTGGAGAAGAAAAGCTACTTCCTAACATCACAGA +CTGGAAGCACCCAGGTCAGAATTGGAGCCAGAATGGTCTGACCCAGTCTTCTCTCTTACA +GCTCACCACTGTCTCGTATTGTCTTTTAAAAATAATACTGGTTTGAGAGGAGAAGATTGA +TTATTTATGTGTAAAGTAGTCACCCCATGGCCCAGGATGGTCTTATTTTGTCAAAAATAT +GAACAGCAATTCCACTGTGCAGCGCACCAGTCTTGAGAATTGTTAACAAAACAATAAACT +ATTGAATCATCACAACTAAAAAAAAATAAAAATAAAAATAAAATAATACTGTGTATCAGT +CTAAGGCCCAGCACGGTGGCTCATGCCTGTAATCCCAGCACTTTAGGAGGCCGAGGTGGG +CGGATCACCTGAGGTCAGGAGTTTCAGACCAGCCTGACCAACATGGTGAAACCCCATCTC +TACTAAAAATACAAAATTAGCTGGGTGTGGTGGTGCACGCCTGTAGTCCCAGCTACTCGG +GAGGCTGAGGCAGGAGAATCGCTTGAAACTGGGAGGTGGAGGTTGCAGTGAGCTGAGTCC +ATGCCATTGCACTCCAGCCTGGGTAACAAGAGTGAAACTCCATCTCAAAAAAAAAAAGAG +AAAAAAGAAAAAAAATACTATGTATCAGTCTATAAAATGCTTAAAGTCTTTCTATTTCAT +TTACTGGATGAAGGGACTACATTTTACTTGCTCTTGTTTTTCAGGGCTTCTAATGTGCCC +TATGGCTAAAAGTCCAAAATTTTCAAAGAATTACCATGGAAACTCTCAATTTTTGGTCTC +TAATATATTGAAATTTAATACAGACATCATTTCTGAGTCTCTCATCATTTTTGAAATAAA +TGCTCAAAGCATGCCCCCAGCCTCACAAGGAGCCAGAGGGTTGTGGGAAGAACAGGTTGT +GACTTAGCACAGTTTAGCAGCATGATCTATTGAGAGAAAAAGGCCCTTCTACAAGGAGGG +CCAGGGGACTGGGTGGAGGTGGGGAAAGGGGAAGAGAGGGGAGGGAGGGAAGGGAGGAGG +AAGGGGAGGGAAGCCACAATCACTGATGAAAATGCACTTTCCACCAGAGGGCGATATTTT +TGAAAGCTTTGATTTGGTTGCACATGGTACAAAAATGCAGTCATGATAAGCAAAACTAAA +ATATGTTCCTTTTATACTACAAATTTATACAGCAGTGAGTAAGAAAGATTGAATAAAGAT +GAAAAAAGAGTTAGAAATACTTCCTCCTAATAAGGCTGAGGGAATTTACAACTATGTCAA +CAGGGCAAATCTACAAAGGATAGCTTAGGAAGAAATGGACTGAAATTTGAGAAGAAAATG +AGTTGAGCATACCAGGAGATTCAATTTCCAGGCCCTTGCAAAACGACAGACTGAAGATGA +GCATCAGCCCTAAGAGGATCCCCGTGTAGGAGGCCTCTGTGAGTGTGCATGTCTGCCCGA +CAGACGCCACAATCCCAGGAGCAACATTATAAACTGAAATAACGTGAAGTTCTTCTTTAC +TTAAAGAATGTGGAGGGATTTGAATATCATATGTTACAAAACTGGATTTTGCCACAAATG +ATGATGCACTGCCCACGTAATTTCAATGCCCACTGAAGGAGAACAGTGGCTTTGCCATGA +GCAGTCCATAAACTGCCAATGACAGCTGGCCAGGTGTTGGGATGTGCCTGTTATACAAAT +GTGCATGAGACAGAAGCAGATAAAATGGCGAATGAAAGAAATCCTACTACTAAGGAAAGA +AAAGGAAAGTAAATGGGAACCATCAGATAGCTTTAGTTAGACATTCATCGAGAAAATAAA +GGAAACAATTTTTCCTAAGTGCCAATGGTAACAATAAGAACGCTAGGAAACCTCTCAGTT +TTCACAGGTTGCATCTTAGGTGTCTTCAGAGGATATGGCAGTTGTATGGACGTGCACAAG +CTACTTACCTCAATTCCTATTTCAAATCCTCCACCAAGGCCAGCTATCCCAATGGCTGAG +GGTGCAGACCATTCTAATAAAAAAACAAACGAACGTTATCCTAACATTAAAACACCCTCG +ACATGTAAATATAGGAAGGAAAAATGCTAAAATCTAAAGAGTGCTTCTATTGAAAATAAT +GAGACTTGGTATTTCCCCTGATTTTAAAGTGATCTTCAAAAAGAATATGTAATTTTTAAA +AAGTTAAAAATATTTTTAAAGTATTAGATATTCATTATGAGTCTCATAGCCTCACAAGCC +CATGTCCTCTAATCTTTCTCTACCAACATGCATAAGACCACCAACTACTGGTTCCCTAAC +CATTAGCCATACAGAGCACTTGGTAACTTCAACTGTCAATATTTTTATAGAACAACTTAG +CTGTAGGTCTAGTCTTCAGCTAGAATTTTGTCACAGATTTAAGAGATCAGAAGGATTCGA +GAGAGTTGATTATCTAACGGTAACATAATAATTGTTTCCATTGTAAATTTCTGAGGGCAA +AAACTGTTTTAACACCTCTCGTGCTTAAGCAGAATAAATAGGCTATAAATTCAAGGTTAT +TAAAATTCTAACAAGATAAATCACATTTAGAAACTAAGTACAGTAATTCCATTTGCCATG +ATACGGCACATTTTAGGATTACTATATGCTTATTTTTCTTGATATAGAAACTCATGTTAA +ACAAGTCTAGAAAAATGTATTTTCAATTTGGTGGGGGGATGGTCTGGCCAAAGCACTTTT +TGAAAATGGTTGCTACCATGCATGCTAGATACTAGAATATTGCTGAAATATATCCAGAAC +TATCCTACCCAGGCTTAGAGAAGTTTGGCTTACAGAAATTAGTGTCTGATAATTTTTCGT +TCCCTATGTTAGGAACTGTCCCTGTGTTAAGATGGCTGGTCTTGGCCAGGATCCTGGGGA +ACATGTTGTGTCTTATTTGGACAGTTTTTAAATTACTCTCAGCAGAGTCAGCAGCTGCAG +CTCAGGAAGAAGGGAGAGAAATGTAGGTTTTAAAACCAGTAGAAAGGTTTGCTGGGGCTC +TGAGAGGAGCCCAGGGCTTGGTATTGACTGTCCCTACCCTTGGTCAGCAAGTCACCCCAT +CAATGGAGCAGTTGGGGACCTGAGACATGCAGGGACTTTCTCACAGACTCTGAGTCCCAT +CTGACAATGGGCTCCCTTGGAATGTGCCTCTACTTTGTTTGGTTTTACTGCTGAGAAGTC +TGCTCATGGAAATTTGGATAATGCTTGAGAAAAAGAGAATTATTTTCTTCTCATTTTCAA +AGCCACACATTGAGCTATGAAAACTGATCCACATAATAAGGAAGAGGTTTTTGTTGACTG +CGGGGATACCTTGGTAAGAAATGGTGAATCTGCTGACTGCTATTTCAAGGCCATATATTT +CACAAATGTATATATTGTATATTTATTGTCTGTAAGTGTCCCATGCTCTCTCAAAATAAA +ATAAAATTATGCTAAAAAACTGCTACTAATAGAAAAACGTGTTCACTGAACAGCAAATGT +TAAATTGGTATAAAAAACATTTTAGTTAGTTTTGACACACCTGTGTCCATTTTAAATACT +ACTATAAATGTTAGTACTTGGGATTCATGGCAAATATTTTGATTTCATCTCTAAAGAATC +AAGTAGTAGATTTCATCCCAGAAAGTAAAACTCGATGATACTGCTCTTGATATGATTCTG +CCTTGGGGAAAACTCTTCAAATGTCACAGTTTTTATGATCTACCACAGAAACAAAGAAAT +TCACATATGGCCCCTTATTTTCATATCAATTTCCATAAAACAAAAGAAAGCAGCTACACC +ATGAAGTTGAGGAATAAGAATTCATATTAAACAAAAGAAATGCACATACTGCCATGTTTC +AATATTTGCTCCACGGAAGAATTACAAAATGCATGCAAAACAAAGTTATATCTACCTGTC +TTGTCTTCTCTAATATTTTGAGGACAGAGAGAGACGGAAAGGCTGGTTCCTGTGGCTTGT +TCACTGACACCAAACTGCACGTTCAGTCGAGTAGCCCTTATTACATAAGTTTTAGTTGAT +ATGCAGGAAACCTGTCCTACTCGCTATGCAATGTGTTCACATGAAAACAGACAGAACAAA +GAATGAAGACTCTCTACTCCAGTGAACAGACGCCAACTTACTTCCATCTGGAAGGCGCGC +CACTACAATCCCGCTGCCTCCTCTGGCAGTCACCAGGAACCCGGCTTTGATCACAGACAG +AATTGCAAGGCCTTTAGCCTTCGCAATTACGTGAGCTGTTAACGTGGAAAACAATGGGAA +GGTAAGCATTTTGATCTATGTGCCTGGATAGACGAGCAAGTGTTAAACAGAGTCAGTGTA +CACAGAGGTTATCTCTAGGAATTCGGGGCACACAGGAGCAATGAACAAAAGTCAGTCACT +CAACAGATGGGCACGAGGCCTCTCTATTCCCATGAATGTTTTTTGTGTTTGCTATTTTTG +CAGTGCTAAACACAACATCATAAATATCCTCACATCCTGTAACTGACAAAATAAATTAGA +TATTTGAAAGAGATTTTATTGCTATCTATTAGCAGGGCAAATATTTTGGCAATTTCAATT +AATTTAGGATATAGTACATAAAAGATAAAAGCTACATTTTCAAAGAAATTAAGATCCATA +TAGTATTAAGGAGAAACTTTAAAAATTACAAAAAGGCAGCATGAATTAGAACTTTGATCT +TAAAGCCACGTAGCTAAATTAACCTTGTATTAATATAAAAATTTGGATTCAAAAACAGAA +AAATTAAGTAATTTTCCAATGTTAAAACATTTTCAACTTTATAAAATGATCTGCTATAGC +ATTTGAGTACCACTTAACTATTAGTACACTGATAATATAATTCCATTTAAAAATATTGGT +TTATTCACATGTCAGAGATGTTCATTACATAAAATGAGGGTTATTGGTATATGTATCCAC +TGAATATAGTGCCACACGATTCTGTGAATTTACGACACAATAACACCTCATTCAAACTAA +CGAGGGAAGCCTAACATATAACTTTAAGGTAGTTTAACTTATTATTATTTTTATCAAATA +TTCTGCCAAGGAAGTGAAGTCAGACATGGGGCTCTAGTACACAGAGCAAAAGCTTTGCAG +ATGACCCAAGAGAACACTAAAATTCTCATGTAATTATGCCACCATTTCAAAGTTTAAATT +AAGAACCGACTCTTGGAAATAATTCATCCAACACCATGAAGTTTGCATGCAGAACATTTG +TGGAGCTGTTCTTAATAAGAAAGCTACAGAAAATAAGGTTGCATCCTGGATGGCTGTCTA +CTAAGTGTACTTTATTTTTGTATTTTAAAAGGTTATAATTATATTGTAACAAGATTGAAA +GCTGTATTATATGTTGTGCAGATTTATTTTTACAGCCACCTGTTGGCAGAATGTCTTCCT +CACATTCTGTTCTCGATGCTTCTAGAGTTGCTATTGCCCCTATTGGGAATATTAGATATT +AACAAAAGCACATTTTAAAATGGACATATTCCACATGTCAATTATATTTTTACAGATTTC +CACTCAAATTCAGGGACACTAACATATTAATAATCCCTGAATAATCTGCCAATTAGCTTT +TGATTTATAACATAGAATGTACCAATTATAGATTTAATTGCTAAATTAAGTTTCACCTAC +TTCTTAGAATCCTAACATTAGAGGAGGCCAAACACACCACTGGGAAGGTTTTAAGATCTA +GATGTCTTGTTTAAATATTTTGTAGATGCAACTGTTTATCCTATGAAATAGCATCTTTGT +TTTAATGTAAACATAATGCCCCCCACCAGACTCCCAGGAGAAGTGGGCCTGGATCTCTGT +TGGCTGTGGAACTTCCATCGTTGCCACACCCATGCTTTGGGGCAATCTCTTACTTAGACT +AACATGCAAACAGAATTTCTTTTTCTGAGCTTCACCCACTGAGACGGGCTCCTTCAGAAT +ACTGATACTGAAAATCTAGTTTTTCTTGTTGAGTTTTCTTTAAGCTCTAAAGCAGCGCTT +CTGAAACTAGTGTGTGTGTGCACCTCACTGGGACCTTGGGAGGAATGCAGACTGATTTGT +GACGTCTGAGCAGATTTCTCACAAGCTCCCAGGGGATGCCAAGCTGCAGATTCAGACTAT +ACCTGGAGCAGTAAGGCTCTAACAAGCACCGTTTCCTCAAGACAGGAGAAGTCACCGGGC +CAATGCAACAACAATTAATATCATGATTAAGATTATTAAAACAACAACAAATTTTTAAAG +CATTAAAGTTCTATTAAATAACTTTAGATATCTGGCTTAGAAAAATTAACTTTATCTCTT +TAATGCAGGACCCAGAGTCATGCACTCTGATTAACTAAGAGGGAGGCTGGTCTGTAACAC +TGTCCAGGCTAACTGGCATGAGACAAGTATGCTATGAACACCCTTTGGAAATAACTAGAA +GTGGTGATGAACAGATAGTGGTTTTCAAAGGCTCCCCTCTGGACTGATCTTATGTGTCAC +TGACTACTTAAGAATTACATGAGAAACATGTTTAAAACATGCATTCCTGGACACACTGCA +CTAAAAGTCTGATTCAGCAGGTTTGGAGTGAGGTTTAAGAACTGTGCCTTTATGGTCTAG +GGGATACTGATGCACATCTGTGTTAGGAATTACTGATTAATGTCTTAAACCGCTAGAGAA +TGTAAATGTCTTATGTGGAAGGAGGAAACACAAAATTAAAATTTATGTATGAGATTAGCT +GGTGAGTTTGCGAGGTTAGCTTGCAGAGTTCTTAGCACGCGATGCAAAGGACAGGCGAGG +CTGCAGAGAGCTCAAGTGGAGCAGGAACATGTGGTGTTTAGGGCGCTGGCACCCTGGGAT +GGGAGGCAGGAGAAAAAGCCTATGCAAAAGGGAGAGACAGGGAGGGAAGAGGCCCTGCTG +GTTTGCCTGGTCTGCAGCTGGCCCTGTCCAGACCCCTTCCACCTGGAGTAGCAAGGCCTT +ATGATGACTGTTTTCTCATGATGGGAGAAGTGGCAGGAATGCAACAATAATTAATATCAT +TATTTTATCATTATTAAGATTATTCTATCAATAACAAATTTTTAAAACAGAGCTCAGAGT +CACGTGCTGTGATTAATTAAGAGGGAGGTTGGTCTGTAACATTGCCAAAGTTAATTGGCA +TTTGGATCTCCTTTGCATGAAACAAGTTATGCTGTGAACACCCTTTGGAAATAACCAGAA +GTTGTAATGAACAGGTAGTAGTTTCCAAAGCATCCCTGGATCAGTCATGAGAAAAAAGGT +GGTGGAACAAAAGGTGGCTGAACTACTTGTTGGCATTGATGGAGGCTTCTGCCTGAAATG +GAGTGTCGAACAATGCAAAAAACAACTTAGGAAAAAGACATTTAGAGACAAACAGCACTC +ATCCTATTTACCTACCAGGAATGATCTTATCAGGTCCATTTCTGGAAGTTATTTCTGTGA +ATTCTCTTAATATTTTGGCAGCCTTTTTTGCTTCTGATTTCAAATTGGAAGGTATAGGGT +TATTCACTGAAACATAACAAAAGATATTTTAATGAAAAATTCTGCTAAATAGAAGTGAGA +AATTTATTATTATTTCATTCTTCTCATATACAATTGTCAGAGGTGTTCAAACCAGAGGGA +CTCCATTTTGAATAGGAGCTGGGTGAAATAAGGCTGAGACCTACTGGGCTGCATTCCCAG +AAGGTTAGGCATTCCAAGTCACAGGATGAGACAGGAGGTCCGCACAAGATACAGGTAACG +AAGACCTTGCTGATAAAACAGCATGCAGTAAAGGAGCTGGCCAAATCCACCAAAACCAAG +AAGGCAATGAACGTGACCTCTGGTCATCTTCACTGCTCATTATACACTAATTCTAATGCG +TTAGCTGCCAAAAGACACTCCCACCAGCGCCATGACAGTTTACAAATGCCATGGCAACAT +CAGGAAGTTACCCTATATGGTCTAAAAAGGAGAGGACCTCTCAGTTCCGGGAATTGCCCA +CCCCTTTTCCAGAAAACTCACGAATAATCCACTCCGTGTTTAGCATATAATTGAAAAACA +ATTGTAAGTATCCTTAGTTGAGCAGCCCATGCCACTACTCCACCTATTGAGTAGCCCTTC +TTTATTCCTTTACTTTCTTAATAAACTTGCTTTTACTTTATGGACTTGCCCTGAGTTCTT +TCTAGCACCAGGTCCAAGAACCCTTTCTTGGGGTCTGGATCGGGACCCCTTTTTGGTAAC +ACAATGAAGCATTACCACAGCATAGCCTATCAAAGGAAATGACTGGAAATCCTCATTGAC +AGTATCATCTCTATTTCTCCTAATAAATCAAATCTATGCTGAGAGTCAGAAACTCTAAAC +TCTCATCTCAGAAATTATAAAATCCTTGGGCCCCAAAGGATGTTAAACAAAACCTGGCCA +AACCTCCCTGTTATGTATCTTCTTCCTGCAATTAACAGACTTCAATACTAATTTAAAATA +AGAATTTAAAATTTAAAAATATATTTTGTAACTATCTATAATATATAGTATAAATTTAAT +ATATTTTGTTGTTCTTGCCAAAAATGTTGGAACTGGCTGCCTGTAGACTTTCTGATGAGT +AAAACTCTAGGAAGACTTGGGAATTGAGCCTACAAGTAACGCCGGCCTGCATTTCTATGG +CACTTTACGTTTACAGTGTTGCCTGGACATTCATACACTCATCAGAGGGCTTGTCATAAC +AAAGCTCACATAATTCTTCCAGCTCTGAAGTATATCGAGAAGATAGACTATTCTCTTGTT +ACTGGACGAGGGATCAGCAGAGCGAAGAAGCTGAATAGCTTCAGTGTAGGACCACAAGTG +CCCTGAGGCTGAGAAGTTCTTGTCTCACTGTCTACAATTAGGAGGCACATGCGTGACTGA +CTGCAGGATGCCAGGATCTGGAAGGTTGAAGGCATTCATTTCCACTGTTTCGCCTCAGTA +ATTTACAGAACAGAGATGAAGTACGCTAATGGAAGCTTGCTTTTGTAAAAGGAAAATAAA +TCTCAGGACCCCAGAATCACTGAGCCAAGGGAAAAGTCAAGCTGGGAACTCTGTGAGGCA +AACCTGCCTCCCATTTTATTCCTAAAAAGATAGCTACAAAGGTAAGAAGCTACACACCTC +CCTCACAATTTGATCACAAGGAAATTCCCTGTGGACAACAGATGGAACTCAGACTCATCC +CTCTGCTCACGTGAGACAAATGCATATCTGATTGTTTCCTTTGCCCTGTTGTTTCACTAA +GCCAGACTACAGCCTAAGTGACTATTCCTGTAAATCACAAAGGCTAATCAGACACTCAAA +AGAATGCAACTGTTTGTCTTCTATCTATTTATGATCAGGAAGCCCCCTACCCACTTCAAG +TTGTCCCGCCTTTCTGGATCTAATCAATCTTACATATATTGATTGATGTCTCATGTCTCC +CTAAAATTTATAAAACCAAACTATACTCAAATCGCCTTGAGCACGTCATCAGGACCTCCT +GAGGCTGTGTCATGGGCTGTCCTTAACCTTGACAAAATAAACTTTTAAAATTGATTAAAA +CCTGTGTCAGAGCTCATGTATAAACTCATGGTTTATTCTTTCGACAGATCAAATGCTGAA +ACAGCAGAGAAAAAAATCCCTTTCTTTTATTCAGCAAAATATAAATATCTCCAATAAAAT +GTGATATATTTTGGTGCCTGGAATGTTTGAAACATGTAATTTATCTTAAAAGTGAAAACT +GGCTGGGTACTCCCAGCACTTTGGGAGGCCAAGGGAGGAGGATCACTTGAGGCCAGGAGT +TCGAGACCAGCCTGGGCAACATAGTGAGACCCCCATCTCTACCAATAAAATGATTTAAAA +AATTAGCCAGTCATGGTCCTTGCTGAAGTCCTTGCTACCCAGGAGGCGGAGGCAGGAAGA +TCACTTGAACTCAGGAGATCAAGGCTGCAGTGAGCTATGACTGGGCTACTGCACTCCAGC +CTGGGCAACAGGGCAAAGCCCTGCCTCAAAATAAAATAAAATTTTAAAAAGTGAAAACTG +ACTTAGGGTCATTTTGGAGTTCTATTTAAATTTCTTTAAAAGATGTCAGTATCAGTTCTT +TGTGGCTCAACACAGGAGTATTAACAAGATCCAGACCAGGAAAAAAATCCATCCCAAGAT +TCATCAATGGTATTAAGTCAGATAGAGGAAGGTATTTCCACAGATACTTTATGCAAAATT +AAGTGTGCATGATGCATGTGTGTAGCTCTTTACTCCTTTTAAAAACAAGTGGCATCACAG +CATTAGTGTATTTTGGCATGTTGCATTTTTTAATCAATGTTATCTCAGAATAGTTAAAAT +ACTGCCTCTCAGTGTAGGCTTTTCAAATCAACTTCATGAGATACAATTTACAAAATGAAA +TCTACCTGTTACAGGTATAGCTCAGTGTGCATGGACAGAGGTAGAGACCACTCCTGATCA +CAGCATCCGTGCCCTCTGTAGTGGTCACTCCTATACCCAGCCCCTGCCTCAGGTTAGTGC +CAATCTGATTTCTGTCATTAAGTATGAATTTTGTCTGTGCCAGAACTTCATATAGTCATC +AGTGTGTGTTCTTTTCTGTCTAGCTTATTTTACTCACCATGAAATTACTGAGACTCAAAT +TGCTGCACAGATCAGCTCTTCCTTTTTGACTGCCAACTGGTATTCTAATGTGTGGACATA +GCACAATTTGTCCTTCCAGTCACTGTTGATAGACAATTGGGTTGTTTCCAGCTTTTGGCT +ATTACAAATAAAACTGCTATAAATATTCCTTTGTAAGCCTTTTGTAAAAAAATGTTTTAT +GGCCGGACACGGTGGCTCACACCTGTAATCCCAGCAATTTGGGAGGCCGAGGTGGGGGGA +TCACCTGAGGTCAGGAGTTCAAGACCAGCCTGGCTAACATGGTGAAACCCCATTTCTACT +AAAAATACAAAAAATTAGCCAGATGTGGTGACGTGCGCCTGTAATCCCAGCTACTCAGGA +GCCTGAGGCAGGAGAATCACTTGAACCTGGAAGGTGGAGGTTGCAGTGAGCCGAGATGGC +GCCATTGCACTCCAGCTTGGGCAGCAAGAACGAAACTCCATCTCAAAAAAAAGAAAAAGA +AAAAATGTTTTATTTCTCTTGGGTAATTACCTAGGATAGGAATTGCCAGTTCATGTGGTA +AATGTGTATTTAACAATGTAAGGAGCCACCTAAGAGTTCTCTAAAGTGATTACACATTTC +AGGCTTCCACCAGAAACTTTTATAAGAGTTCTGGTTATTCCATATCCTCACCAACACTTG +CAATGTCCAGTTTTTAAAATTTTAGTTATTTTAGTGGTACACAGTGGCCTTTCACTGTGG +ATTTAATTTTCGTTTCTCAGATGACTAATGATGTTGAACACTTTTTCCTATTTCTATATC +TTGTAAAGTGTCTGCTTAAATCTTTTGTCCACGTCCTTTAACCACTTATTATTATTATTA +TACTTTAACGGAGTTGTTTTTTTGCTTGTTAATTTGTTTAAATTTCTTATAGATTCTGAA +TATTAGGCCTTTGTTGGATGTAGAGCTTACAAATATTTTCTTCTATTCTGTAGGTTGTTT +TCTCTGTTGATAGTTTCTTTTGCTGTTCAGAAGCTCTTTAGTTTAAGTAGGTCCCATTTG +TCAATTTTTGTTTTTGTTGTAATTGCTTTTGGCATCTTTATCATAAAATCTTTGCCAGCG +ATTATGTCCACAATGGAATTTCCTAGCTTATCTTCCAGAGTTTTTACAGCTTTAGGTTTT +ACATTGTTAAAACAGGCTAAATGTGACCTGAGAAGAACTCCATACTTCAATATTTGAGTC +CTTGTAGATGAACTGCCACCTAACTTAATATGTAGACAAGATTGAGAACTTAACTTAGGA +GTATGCATCTGTAACAATAGCTCAGTCTTGGCCAATCCCAGCAGCCATACTTCAACCACT +CATACACTGCTAAGTGTTCACATAAGGAAAATGATGAGCTGTAACCAATCCAGTTGTTTC +TGTACTTCATTTCTGATTTCTGTACGTCACTTCCCCTTTTTTGGTCTATAAATTTGTTCT +GACCACGAGGCATCCCTGGAGTCTCTCTGAATCTGCTGTGATTCTGGGGGCTGCCCGACT +TGCATATCATTCATTGCTCAATTAAACTCCTTAAAATTTAATTTGGCTTAAGTTTTTAAC +AACATTCAAGTCTTTAATCCATCTTGAATTGTTTTTTTGCATATGGTATAAGGAAGGGGT +CCTGTTTCAGTCTTCTGTGTATGGCTGGCCAGGTATTCCAGCACCATTTATTGAATATGG +AGTCCTTTCCCCATTGCTTATTTTTGTTGACTTTGTCAAATATCAGATGATTGTAGCTGT +GTAGCATGAATTCTGGGCTCTCGATTCTGTTCATTGTTCTATGAGTCTGTTTTTGTACCA +TTACCATGCTGTTTTCATTACTGTAGCTTTGTAGTATAGTTTGAAGTCGGGTAGCATGAT +TCCTCCAGCTGTTCTTTTTGCTTAGGATTGCCTTGGCTATTTGGGCTCTTTCTTGGTTCC +ATATGAATTTTAAAATAGTTTTGTTTTCTAATTCTGTGAAGAATGATATTGGTAGTATAA +TAGGAATAGTATTGAATCTATAAATTGCTCTAGGCAGTATGGCAATTTTAATAATGTTGA +TTCTTCCTATCCTTGAACAAGGAATGTTTTTCCATGTTTGTGCCATCTCTGATTTCTTTC +AGCAGTGCTTTGTAATTCTTGTTGTAGAGATCTTTCACCTCCTTGGTTAGCTGTATTCTT +AGGTATTTTATTCTTTTTGTGTAAAATAGGTGTTTTAAATTGTATAATCTGCCATTTCTC +GATCTGTTTTTGACTGATTCTTCTTCCAGCTATGGGTTATGTTTTCCTGTTTTTACTCCT +TTCTAGTAAAACAGGATTGTAGATATTACCATGTTGAGTGCCTAGATTTCATTGCTTCCC +TTAAAAGTGTTAACACTTGTGTTAGCAGGCAGTGAGTTACTTGTAGATCAGCTTGATCAC +TTGTTGGCTTGTTGTTGTGTTCTGTTTGTGTGTCTAGAGTAGCCTTTAGAACTATTTTAT +CCATCAAGGTGTGTCCCTTCTGGGCTCTCTCCTGGGTGCCCTGGTTGTTTAATAAGCTGT +CTCCATTGTGGCTGTTTCGAATGGCTGTCCCCAGCCTGATGCAAGCACTGTGAATAGTTC +ACCTCAAAGCTTCATGGCAGTTGTTCTTGCCTGCTTTGCAAATTTCACCCTACACAGCTA +GCACTTAATATTCAGCAGAAGGCTCAGGGGGATCCCTCTGCAGATTTCTGGAGCTCTTTC +TCTCAGCCGTCCCTCATTGCTAGTAACATGCTCTGCAAATTCCAGTTACCTCAGCCTCTT +CAGACTCAATTTCTGCCTCTTCTTTTAAGCAGGAGCCTGGGCTCTGGGTGCCCCCTCCTT +GTCCTGCAGTTTAGGAAGTGCTCCAGGCAGAAAACGGTCACTAATGGAGTTCACCTCCTG +TTCCCCTTATCTTGTGGATCTCAGACATGTCCACCATGTGCAAAAAGTGCTCTACACACA +GCTGTCCAGTTTCCTAGCTGTTTACCATGTGTGAGTAGCAGGAGCCATTTCGCTGCCCTG +GCCAGTAGCTCTCAGTGCATTTTCCATTTGTTCTTTTATGATGAGCAATGCTGACCACAT +TTCACTCTCTCTATCAAAGGTTTCTCATGCACCTTGTTATTTACAGGGGGTTTCTCTCTG +TTTCTTATTAATTTATACATTAAAAATTAATATTTTTTTGGAATATGAGTTAAAAACATT +GACTCTCTGTTACTTGTCTTTTGAATTTGCTTTTTTTTCTGTTTTTTCTTAATGAAATCA +AATCTGTCTTCTATCTTACAAGGGTCTTTTAATAAAACACAGTAATTTTGAAGTTCAAAT +GGGAAAATAAACAAGCAAGAAGAGCTAGGAAAAAATATGTAATAGGAGAACAATGACAGC +CCAGCCTTGACAGAACCTGTGACACATTACAAAGCCTCAATAATTAATACATAATAGCAG +ATGCAAATATAGGAGAAAAATCAATTCACAAAGAAGAAAATTCAGAAATTAACCCAAATA +TATTTACAAATTTAGTATATAATAAAAATGACACCTCAATTCTATGTTGAAATGATGTAT +TGCATACTAGATAATGTTCATTTGGGGAGAAAAACAAAAATTCATTCACAGCTTTGTGTT +ACAGAAAGATAAACTCCAAATTCATTGAAGATTTAGAGTGTCAAATATCAAATTATAAAA +GAACCAGGAATTATAGAATTTTTTTTCAATTTCATAGTGGAAAAGACCCAAGTATGGCAA +CAAAATTTCTATATTTCTATATTTTTACATGATCAGCAATTATTTGTACAACGTACAAAT +ACATTGTAAAATACAGGAAAAAGTACAGATATGAAAATATGAAGGATAAAAAGCATCTAT +AACATTAATACTCACCAATACTACTGTCTGCATTTTGATGTATGCTTCAATTGATTCCTA +TTGCGAAACATGTAGACTGATTCCACTTTTAGCTTTTATAGCCATTACTATCAGGTGGTA +ATTATCTTGGGAGAGATGCTCTAGATGCTCAATATGTTTTAATTACATTTATACATATAT +CTAGATGCTGGATACATTTGAATTAGTTCACTGGAGTGGAAACTTGTTCTTTCTGCTGCT +GAATATTTCATCTACTTTATTTCAGAGGCAGCACAACTTGTCTGCTTACATTGATGCTGC +AGCCATAGTATCTGGAGTGGATTGGGTGACCCGAGGCTGCTGTATCAGGACGACATTCCT +TTTGGTGCCACAGCAGGGCTTTATAACCAAAGCTGGTCCAATACCAGCATCTGATGGGGG +ACTTGTATAGGAGCTGCCAGAATAACTTTTTCCAAGGCACTTCTGTTTCCACTTGCTGTG +GGATTTTTGTCTCCACAAGGGGAGAGTCTGAGAGCAAAGCCTTCATAGGGGAACCTGGCA +GAAGGTGGAGAGAGCACCTGGGCTCTGCAAAGCCAGACTGAAGTCACAAGCCGCTCTGGA +CTTCTTCGTCAAATGGACCAGCAACATCTTTTTCTGTTAAAGCAATTTAGACTAGATTTT +CTGATACATGCAACTGAAGCACTGTAAATAATACATGAATCTTATCCCCTCAGAAGACTT +TCTACTTTGAACTCTCTCAACCAAGCAGTATTAGAGCAAATAAGCAAATTCCTCAGTTGA +GAGTTAATCTTGCAAACATCCTGCTGTAGGGAAAGGTCATGGCCTGATCTGTAAACACGG +GAAGAGAGCCATTGGACTTGGGAATCAGATGCAGCCTCACACGGCTGCAGACCGCAAGAC +TCATCCTAGACACAGCTTATGTCACTGTGATCCAGCTGTTGACAAGGCTGGTCACAGTGA +GGACATCTTCAGTGTGTCAGCTGAACTACAGAAAATGTTACAGATTCTAATCAACTTCTG +ATAAAATCATGCGTGGTCATAGTTACATGCAGTGAATTTCTCTGTCAGAACAAAAAGAAT +ATGCAAATAAAAATTTAGACATAAGCCTCAAATCCCATCCTCAGCATCAAATGATGGCTC +ACCCATTTTTCCTCTGCTGTACCATAAGGCATATAGAGCATGACCTGATCAGAGTGCTGA +TGTCCCATTCTATCATACTGATGAAGACACAGGTCATTACTAATGAAGCCTCTTAAACCT +CACATCATGGTTAGCATCTGCACTCTCATAAACGTCTTAAGTCCCTTGAATCAGGCAAAA +TCTCTATAAATATTTAAGTTTTTTCTAAAAAAAGAGTGGCTGCCAAACCTCAAGCTAAGA +AACTTTCAAATAAAGTTTTCTTTAAAACAAAAGTTAAAATGTTTTAAATTTTCATAGTAA +CACATTTTTTTTTTAAATTAGAAGGTCTTATAAAATACCGGAAAGACAATTTTTACTTTG +GAAACCTCAAAAGCATAAATCAGCTTAAGATCTGGAAATAATTTTAGGTATTGATCGCAG +TTCTATAAACTCAATGCTAGAGTCACTGGGGACAAACAGGGACATGAGAATCCTACTCGG +AGTAAATTGCCACCTGAGGTGACAAAGCTGACTACGGTTTCCAATCTAGTTGTACACGGA +GGGTCAGGAATGAAAGCAAGAAGACCCAAGGGCCCCTCTCCACCACTTTCCTTACCAGAG +TTCAGATTCCCAAACTTTTGCTTCCCTTATATTATTTTCTTCAATGGACTCTAATTATGA +AAGGAATACTTACAGGAAAGCAAGCTTACTAAATTTGGTTTTCCAAGTTCTTACTGATTA +CATATTAATCAAATTATTAAACCTTATACTTTATGTGAAATGGAGGTTAACTCATTAAAC +TGATAAAATTCCATCTAAGATCAAAGGAACTTGAATGCTGCTAAAGGTATATTTAGAATA +AACTAAAGAAATCTTAGCCAAAAGAAAGTGTATGTATCTAATCTTTAGAGAGGCTTTCAA +ATGTTGCTTTAAGCTACTTTTATTAACAAAACTGCATTTTGAACTCCACTGCTTGACAAC +TATGGCCTTTGTTTCTTAAGTCAATTCTTACCTTTCTGGGGCCTTGGTTTAACTACTTCC +TTTGTTTTAAGGACACAAAGCTTGTCAGTTCTCAAAATAAAAACCTGTCTCTCTGGTCAG +ATCATTAACTCCCTAGTCAAACTTTCAGACTACCGTCTGAACATCAAGTGCTAGCCTGAG +CTTGTTTCCAGTCCCCCAACCCCAGGCTGTGGCTGGGGAAGGAAGAGGACAGCGAAAGCT +TTCTCTGCTCCCTCGGGAGACAGGAAAGCCCTTTATTTATTCCTGCCCTTCCTCTTCTCC +AACTGAAGAGTGTGATCTTGGTACAGAGCAGTTCCACACATGCCACACTGGTCTGATCTT +TTAGAGTAAAAAATGGGATCTTCTCAGAGAAAATTTTTTTAAAAACTTCATGTGCTTAGG +TCTCAGAGCAGAGAATTTTGTCTTATCATGACGCCACTCACTGGCAAACAAGCTGGCGTG +CACAGGGACTTGTGAGGCTCTCAGCAGAGTCAGGGTAGCAGTTATTTCCCTTTGACTGCC +TCAACTTCCTATGTTTGTGTTGACATGCCAGATCCTTATTTCTGCGGAATGAGAAATCTC +TTGAGAATAAAGTTTTCCTAAACAGAACAAAAGTATCAAATCACTTTTGATGAGCAAACA +TTATTTTAAACTTTTTTTTAACTTACAAAAGATGAGGGGTAACATTTACTAGTTTTACAG +AAATTTTCTTTAAACAGAACATTAGTGAACCAAATAACCAATTCTCCTCAAACATGATAG +ACAGGATGGAGGTTATCACTTTGATCATTTTAACCTCCAACATAGTAATTTGTAAACATC +AGTCGCTGCACAAGTATTTTAATAACAGGCCAGCCCACGGGAGTAAACAGCACCTTAGCC +TCGAGACCTGTTCTCTCAACTGTGTGTACAGATTTTCTAAGTCGTTATGAATTCAGATAT +TCCCTACATCTCAATAAAAACACCTAGGAGAACAAGAAATCAGGACATGCATCTCCTGTA +AGCAGAAGAGAAACCGAGCACCTGCTCTCTTGCGGGGGGGCAGCTTCGTGTCACTTTCCA +ACTCAGCCTCCACAGGAGCATGGGCATATTGGTTCAAATGAAGTGTAAAGGACACATCTC +TGTCCACAGTGTAAATCCTATTTCCTTAAGGTGGTCAACCGATTGAGACCAGTTCCACAC +TTCCTTAAAGAAGGAAAAACTCAGCAGCCAGCGCCAAGGCCCAGCGATCAGAGAGGACCC +GTGCTCGCCGCGACCCCGCGCTCGCCCTGTGGCCCCGCGACCCCGGCGCCAGGTGTTGGG +GGGACCGGCCCTTCCCTTCCGGGTGTGAGGGGCTGGCCCTTCTCTTCCAGGTTGGGGGGC +TGGCAAACTCGAACCTCGCCGGCGCCCTAGCCAAGGCCTCCTCCCCGCGCCTGCCGCGGG +TTCCACGCACATTCCAAGCGCGCGCATTCGACCCAAACTTCAGAGACGCTTCTGTGGAAC +GGAAGGATGGTCGCTGACACCTCGCCGTTCAAATATCAGGAAGTTAAAAATAACACGACC +ATCGTCATCATTCCAAACTTCGGAATAGCTTTTCTAAAAATGGAAAAGACGGTGGCTAAA +CTTCAATCAAAATCGCTGTGGTCAAGAAAGTCCTGGAAGCTGCTCTATCTTAACTTTGGG +CGGTTTGCGGTTAACAGACGCGCGACCTAGAAACCCCAGAGGCATCGCCGGTTTTCCCGT +CCTCCTCCTCCCACCACCGCCCAGCTCTTGAGAGGGGAGGGTGCTGCCGGACAGGTGGGT +CCCCGGGTACTCACTGCTGCCCGCCCGGCCGCGGCGCCCCGTCCCGAGGCTGCCCAGGAA +GAGGAAGGCGCGCTGCCCCGCCCCGCGGACAAGGAGGCCCCAGCGAGGGCGTACCTGCGG +CAGGTGACGAAGGAGGCGGCGCAAAACACCCGCCGTGTACGTTTCGCGGGACAAAAACCA +CGCGCCCGCCGGGCCGCGCTCAGGCCTTCGCCCTCAGGGACTTCGGAACCGCCCCGTCCT +CAAGATCGAAAAGCCCAGAGCCCCGCGGCGGCTCCAAGCACGGTGTTGGGGGTGGGGGTC +TCAGGGAGCGCCCAGGCCCAAGGCCGCCCTGGTCCGGCGTGGACCCCGCGGGGCTCAAGG +CAGGTTCCCCGCGTGACCCGCCCAGCCCCTCTATGCGAACTCGAACGACAGGCACCACAG +CCCGCCACGTGCGCGAGACTCGCGCTGTGCCCCAACCCAGGTGGGCGGCCCGCGGAGCCG +CGAGGCCTGAGCCCGCCCTGCAGGTGACCCGCGGCCCTTCCTCCTCCAGGTACCCCTCTC +CTGCGGCCCCGTCCCCTATAGGTAACCTTTACCTCCCGCGGCTCCTTCCCCTCCAAGCGA +CCCGCAGCCCCGCCCCCTCCAGGTGACTCCCCCCCGCCAACCCCCGCCACCACACACACA +CACCCCCTCGCCTTCCGCGGCCCTACTCCCTCCAGGTGACCCCACCCCCGCAGCTCCTCC +TCCTCCGGACAACCTGCAGCCCCGCCCCTGCAGGTGAACGGCGGCCCAGTCCCTGCAGGT +GACCCGCGGACCCTCCCCGCCCGTCCTACTACCGTCATAGGACCGCCTCCGCAGGCGCAC +TGGAGCCGATTGCGCAGGCGTGGCTCTCACACGCGCTGCCCTGTTGGCGTTGGTGCGGGA +CTGCGCAGGCGCGCGGGGCAAGAGGGTGGCAGTGCGCCTGCGCCGCGTCGGCGTGCGGAA +CGCCGCGGTGTCTCGGCGCCTCTGCGCGCGGGAAGATGGCGGAACAGGCTACCAAGTCCG +TGCTGTTTGTGTGTCTGGGTAAGAGGGCGCCGACTTACTCATGTTCTGACGTCCTCTGGA +GAGTTGGATCGGGCTTGTGCGCTGTAGGTTGTGCCGCCGGCCTAGGAACCATGAGGGGGA +GGAGGCCAGGGACTGGGAGGCCTAGGGTGTTCTAGGAGTGTGCCGCAGCGCCCCTGTTCC +CCATCCGCCCCGTGCACCCGCCCAGCCTGCCCGCTAAACCTGGGTCCCCTCGCGCCTGCC +ATATATCCGGGGCTCTTGGCATCTGCAGCCACAGCCCCTACAAGCCAAGGTACTTTCTTT +GCGACTACTAGAATCCCTCTCGTTCCCCTCCAATGGGCCCAGGTAGGCCTGGAGGTTGTC +GGACTGATGTGGTCTCTTAGGGGCCTCCTGAGTCCTATGACAACATTGTTTTGTTTGCTA +GTTTCCTTAGCCCATGCTTAGATAGGGATCTGAGTTAAAGGGAGATGAAGTTTTACGGTT +TCGGGTTTCTTGATTGTAAAAGCCAAGCAAAGGAGACCTGGAGGTCCCTATATAACTTTG +GCCCATGAAAAATGAAAGTGTATTTTATTAATGGCTTTTCAGGAACTTTCCAGCTTAAAT +TATTTTCACTCCTAGAATTTCAACACTTAGCTTGCCTTACTTCAAACATAATTTATTTTC +CGTTTGGTCTTCAGGGATCTTCCTTTGGTGTAGCACTACAAGGTTATATTCCTCGGTGCC +TCCACCCTGAGAGGAAGGCCTAAATTGTCAGTAGTCCGGTTACTTAAAACCTTCTGTGAG +TTTGCATTTCCTGCAGTTTCTGTTTATTTTTACAGACTCCTCACTTTATCTCCTGTACCT +TTTCCTGCTCACACCCTCGGGACACTGCCTTCCAGAACCTTTCGTTGTTCGGTAGCACTT +CACATGCTTACTGAGCCTTCATCGCTGGGTGCCCATTATGCATTTTGCCTGGAAAGCCTT +TTTATTTTATAAAGTCAAACCTAAATATTTCCTCCTTTGCTTTCCCAGATCATGAGTTGC +TTCCTTATCGACATCTTTTATTACACAAATTTTACTATAATTTGTGTAATATAGTAAAAG +ATGTAATACAGAAAAGGTGTGATTCCTTATCGACATCTTTTATTACACAAATTTTACTAT +AATTATTTGATAGTCTGTTGAAATCCCAGCTGAGTTTAATTTTGTCGATGGCAATAACTG +TGGCTTATTTTTCATTTTGTTTTCAGCTTTAGGACAATATATGATAAACGCTGACTAGGT +TTTGTAGAAGTTAACTTCTGTGAAAGACGAATTAGAAGGCTTACCTTGTTTCACATTGGT +AGTGGGCATCATTTGATTTTTAAGACTCATTGAAGGCTGAATGATGAAATCAATAAGTTT +ATTAAACAGTAGTTTGGTTAAGGATGGTTACTAAATAATATTCCATTCC diff --git a/test/csq/ENST00000479739/ENST00000479739.fa.fai b/test/csq/ENST00000479739/ENST00000479739.fa.fai new file mode 100644 index 0000000..5f995a2 --- /dev/null +++ b/test/csq/ENST00000479739/ENST00000479739.fa.fai @@ -0,0 +1 @@ +2 48709 19 60 61 diff --git a/test/csq/ENST00000479739/ENST00000479739.gff b/test/csq/ENST00000479739/ENST00000479739.gff new file mode 100644 index 0000000..de4cd42 --- /dev/null +++ b/test/csq/ENST00000479739/ENST00000479739.gff @@ -0,0 +1,26 @@ +2 ensembl_havana gene 21 48689 . - . ID=gene:ENSG00000035115;Name=SH3YL1;biotype=protein_coding;description=SH3 and SYLF domain containing 1 [Source:HGNC Symbol%3BAcc:29546];gene_id=ENSG00000035115;logic_name=ensembl_havana_gene;version=17 +2 ensembl_havana NMD_transcript_variant 1071 42999 . - . ID=transcript:ENST00000479739;Parent=gene:ENSG00000035115;Name=SH3YL1-009;biotype=nonsense_mediated_decay;havana_transcript=OTTHUMT00000322358;havana_version=3;transcript_id=ENST00000479739;version=2 +2 havana exon 1071 1292 . - . Parent=transcript:ENST00000479739;Name=ENSE00001954076;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001954076;rank=11;version=1 +2 havana three_prime_UTR 1071 1292 . - . Parent=transcript:ENST00000479739 +2 havana exon 12257 12335 . - . Parent=transcript:ENST00000479739;Name=ENSE00003606733;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003606733;rank=10;version=1 +2 havana three_prime_UTR 12257 12335 . - . Parent=transcript:ENST00000479739 +2 havana three_prime_UTR 12838 13259 . - . Parent=transcript:ENST00000479739 +2 havana exon 12838 13482 . - . Parent=transcript:ENST00000479739;Name=ENSE00001945985;constitutive=0;ensembl_end_phase=-1;ensembl_phase=2;exon_id=ENSE00001945985;rank=9;version=1 +2 havana CDS 13260 13482 . - 1 ID=CDS:ENSP00000441266;Parent=transcript:ENST00000479739;protein_id=ENSP00000441266 +2 havana exon 15392 15520 . - . Parent=transcript:ENST00000479739;Name=ENSE00003685079;constitutive=0;ensembl_end_phase=2;ensembl_phase=2;exon_id=ENSE00003685079;rank=8;version=1 +2 havana CDS 15392 15520 . - 1 ID=CDS:ENSP00000441266;Parent=transcript:ENST00000479739;protein_id=ENSP00000441266 +2 havana exon 16451 16563 . - . Parent=transcript:ENST00000479739;Name=ENSE00003571637;constitutive=0;ensembl_end_phase=2;ensembl_phase=0;exon_id=ENSE00003571637;rank=7;version=1 +2 havana CDS 16451 16563 . - 0 ID=CDS:ENSP00000441266;Parent=transcript:ENST00000479739;protein_id=ENSP00000441266 +2 havana CDS 25089 25091 . - 0 ID=CDS:ENSP00000441266;Parent=transcript:ENST00000479739;protein_id=ENSP00000441266 +2 havana exon 25089 25162 . - . Parent=transcript:ENST00000479739;Name=ENSE00001537032;constitutive=0;ensembl_end_phase=0;ensembl_phase=-1;exon_id=ENSE00001537032;rank=6;version=1 +2 havana five_prime_UTR 25092 25162 . - . Parent=transcript:ENST00000479739 +2 havana exon 25794 25853 . - . Parent=transcript:ENST00000479739;Name=ENSE00003646899;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003646899;rank=5;version=1 +2 havana five_prime_UTR 25794 25853 . - . Parent=transcript:ENST00000479739 +2 havana exon 29829 29893 . - . Parent=transcript:ENST00000479739;Name=ENSE00003541607;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003541607;rank=4;version=1 +2 havana five_prime_UTR 29829 29893 . - . Parent=transcript:ENST00000479739 +2 havana exon 32022 32135 . - . Parent=transcript:ENST00000479739;Name=ENSE00003498940;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003498940;rank=3;version=1 +2 havana five_prime_UTR 32022 32135 . - . Parent=transcript:ENST00000479739 +2 havana exon 35296 35406 . - . Parent=transcript:ENST00000479739;Name=ENSE00003522422;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003522422;rank=2;version=1 +2 havana five_prime_UTR 35296 35406 . - . Parent=transcript:ENST00000479739 +2 havana exon 42376 42999 . - . Parent=transcript:ENST00000479739;Name=ENSE00001878590;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001878590;rank=1;version=1 +2 havana five_prime_UTR 42376 42999 . - . Parent=transcript:ENST00000479739 diff --git a/test/csq/ENST00000479739/short-cds-start-lost.txt b/test/csq/ENST00000479739/short-cds-start-lost.txt new file mode 100644 index 0000000..e1ae5a8 --- /dev/null +++ b/test/csq/ENST00000479739/short-cds-start-lost.txt @@ -0,0 +1,3 @@ +25091 T C start_lost&splice_region|SH3YL1|ENST00000479739|NMD|-|1M>1V|25091T>C +25091 T C start_lost&splice_region|SH3YL1|ENST00000479739|NMD|-|1M>1V|25091T>C + diff --git a/test/csq/ENST00000479739/short-cds-start-lost.txt-l b/test/csq/ENST00000479739/short-cds-start-lost.txt-l new file mode 100644 index 0000000..e1ae5a8 --- /dev/null +++ b/test/csq/ENST00000479739/short-cds-start-lost.txt-l @@ -0,0 +1,3 @@ +25091 T C start_lost&splice_region|SH3YL1|ENST00000479739|NMD|-|1M>1V|25091T>C +25091 T C start_lost&splice_region|SH3YL1|ENST00000479739|NMD|-|1M>1V|25091T>C + diff --git a/test/csq/ENST00000479739/short-cds-start-lost.vcf b/test/csq/ENST00000479739/short-cds-start-lost.vcf new file mode 100644 index 0000000..67ee7f2 --- /dev/null +++ b/test/csq/ENST00000479739/short-cds-start-lost.vcf @@ -0,0 +1,6 @@ +##fileformat=VCFv4.2 +##contig= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO +2 25091 . T C . . EXP=start_lost&splice_region|SH3YL1|ENST00000479739|NMD|-|1M>1V|25091T>C;type=ENST00000479739:242800-T-C 3bp CDS diff --git a/test/csq/ENST00000519442/ENST00000519442.fa b/test/csq/ENST00000519442/ENST00000519442.fa new file mode 100644 index 0000000..b4d542d --- /dev/null +++ b/test/csq/ENST00000519442/ENST00000519442.fa @@ -0,0 +1,766 @@ +>5 5:157052667-157098508 +AACAGAAAACATCCAACAAGAACAATTTTATCTATGTTTATTTAATTACAACAAAGAACG +ATGTATGCCAAATGGAAAAAAAATATTTTAAAATGATAAAAATATTTAGAAACAGAAATG +ACTAAATTTAGCTGAAGAATCACCCAGGTGCCATTAAAACACATTTGGAACTTATAATTG +GTTATTAGTGTAAGTTAAATTTAGCAACCAAGTCCAAGTTCACTAGGAGTTGTCAAAATA +CTTTCAAAATGTTACATCAAAAATTGACAACATCCATAAGTATTACATAAAAAGCAAACA +AAAAATCATTTAAAAAATGTATCCTGAGATAAAATAAAAATCACACTATGCTAGATTTAT +TTCCCCTTTCCCCTCACATACAACTGTGAGGCTTCAGTATTTTGCATGTTCCAGGATAAA +GTAATAATAATACATGTTGATGCAAATTTCAGCCATTAAAATTAAACTACTTAATAACTT +AAATATTCCTACAATGAAACATCCAGACTCTAGTTTCACTAATCAAAATTTTATGAAGAC +ATAAATTGCATTTGGTTTTAACTCCTCAAATCACGACTGAAAACTTTCAACAAAGAATTC +TAGGCTTTTTTTTTTCTCATACCAACTGACCCAGAATATATTTTAAGAAATGTTTATTTT +CTGTGCATATTTGTTTTAAAATTATAAATCCCTGAGCACTTTTTCTTCTTCCTCCTCATC +ACTGTCGGTGACATTGACTTGCTGGATGCTAGAAGGAGTTGATGTCGGGGCTGTGAAGAC +ATTCTCCAAGGTTCCAATGTCCAGCTGAGGCACAGGGTTTAAGTTTTCTTCCCCACTGTG +GCTATGACTGTTATAGTAAGAAGTTCCATTCATGTTCTCACAACTCCGAGAATTTTCACT +GTGTGTGCATTCACTTGAGTAGTCTCTAAAAGAATAGTCTCTATTTAAAGTTGAAAAGAT +ACCCTCATGTTTTGGGTACCTGTCTTCATAATAACTAAGGCATTCTGGCATTGAACTCGG +AAAATTTCCATAGCCAAAGGGAGGCCGACTGTAAGGGCATGTACTGCAGCAGAAAAACAC +AAACAAGGAATTAGATCTTGCCCACATATTGCCTTGCATACAGACTAACAGAGCAAGTTA +ATGCCTCCTCTTTGGGGTTTGGAAAGTTCCTTTCTGCAAACACTTCATGTATTCCTCTGC +TCTTTTCCCACTGCCCAGTCCCCACCCACAAGGAACAGGAAAGGGAGCTTGTGACTGGAA +TACTCACCAGCACTATTATCTATCGTTAGCCTCAGGCTTCTTACCTTTGACAACCATGAT +AACAAAATTGCTTATTCTGGTCTTTCTCTCATGATGCCTCATACCATATAAGGTTTTGGA +AATGCAGATGTGTGTTGAGCTATGCTAAGAATTGACACTCAGTGGTTGGGCGCGGTGGCT +CACGCCTGTAATCCCAACACTTTGGGAGGCTGAGGCGGGCGGAACATGAGGTCAAGAGAT +AGAGATCATCCTGGCCAACATAGTGAAACCCCATCTCTACTAAAAATACAAAAAATTAGC +TGGGCATGGTGGTGCATGCCTGTAGTCCCAGCTACTCAGGAGGCTGAGGCAGGAGGATCG +CTTGAACCCAGGAGGTAGAGGTTGCAGTGAGCCGAGACTGCGCCACTGCACTCCAGCCTG +GTGACAGAGTGAGACTCCGCCTCCAAAAAAACAAAAACAAACAAAAAAACCCACAGAATT +GACACTTAGTAAACAATGCAATAGTGCAATAGTTGTTTTTAGTGGTATTTGAAAGGAAGC +TCATGTTGGGGGGGAAATGTATAACTAGATTGAAATCAAGAGATCCAGAATATTGAGGCA +CTGGAACAGAAGACAAGTTAAATTTTTTCATTGACATTCAATAATAAAGTAAATTTAAAA +CACTGTTACTACTAGAAAGATTTGAAACTGATAGTAAACTATGGTCTTAAAGGTCTTTTC +CAAAACATTTTTTGGAGGGCAGGAATGTGAAGAATCAAAAAGACATTTTGCAGTTTTAAA +AGTTATGGTTTTTTGGCCGGGCGCGGTGGCTCACGCCTGTAATCCCAGCACTCTGGGAGG +CCGAGGTGGGCGGATCACAAGGTCAGGAGATCGAGACCATCCTGGCTAACACGGTGAAAC +CCCATCTCTACTAAAAATACAAAAAATTAGCCAGGCGTGGTGGCGGGCGCCTGTAGTCCC +AGCTACTCAGGAGGCTGAGGCAGGAGAATGGCGTGAACCCAGAAGGCGGAGCTTGCAGTG +AGCCGCGATCACGCCACCACACTCCAGCCTGGGTGACAGAGTGAGACTCCATCTCAAAAA +AAAAAAAAAAGTCAAATCCAAAATTTCTGCCATTTGCTGGGCACAGTAGTGCATGCCTGT +AGTCCCAGCTACTCAGGAGGCTGACGCAGGAGGATCGTTTGAGCCCAGGAGTTTGAAGCC +AGCCTGGGCAATATAGTGAGACCCCCATCTCAAAAAAAAATTTTTTTAAAAAAGATTATA +CCTCAAAAATTCTGCTACTCAAACCCATTTGTCAATTGTTTTTAAGTATTATTCTCTCTT +TCAAAGGCATAGAGCAGGAATTATAGGAAGAGGTAGAGTCCAACCATCTAGTGACAGATA +ACATAAACATAATGACCATACTCATCGGCAAAACCCATGGCAAGTTAAGTGTTTCATTTC +TGGCCTTCACACACACACACACACACACACACACACACACACACACACAGAGTCAACTTT +GTTACCTTACTTTTAAAAACCTAAGTATGACAGACATACTAGACTATTATCTCAAACTCT +GAAACTATGCCCTACCCCCAAATCTTCAAGTGCTAGGTACCTTGCTCATGTTAATTATAA +CAAATGAGGTAAAGTTTCTAAAATTTTTCAGGTTTCCATGCCTACTGCCACTCTTAGTTC +GGGCATTTTAAATTTAATACACATGTCCTGAATACACTGTGCTTCTTTTTTTTTTTTTTT +TGAGACAGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGCATGAATTTGGCTCACT +GCAACCTCCGCCTCCCAGGTTCAAGCAATTCTCCTGCCTCAGCCTACCGAGTAGCTAGGA +TTACAGGTGCCCGCCACCATGTCCGGCTAATTTTTGTATTTTAGTAGAGATGGGGTTTCA +CCATGTTGGCCAGTCTGGTCTCGAAATTCTGACCTCAGGTGATCCGCCCGCCTCAGCCTC +CCAAAGTGCTGGGATTATGAGTGTGAGCCACCGTGCACGGCCAAATACACTGTGCTTCTG +GCTAGCACAGCTTTGCTCATATAGCAGGTCTCTCTATCCATTGAATTCCACAGATAATTC +AGGGATGAAAAGAGGCTGACTATGGGTACAAACATACAGTTAGATAGAAGATGTAAGTTC +TAATGTTCAGTAGCACAGTAGGGTGCCTATAGTTAGCAACAATGTCTGGTGTATTTCAAA +GTAGCTATAAGAGAGGACTAAAAATGTTCCCAATATACAGAAATGATAATCAAGGTGACA +GATAACCCAAATACCCTGACTTGATCATTACACATTTTATACATATTTATGACAAGTACC +CCATAAATACGTAAAATGTTATATATCAATAAAATAAAAATCTATCCCTTCCACAAAGCC +TTCATTTCAGCTAGAAATAATTCACCCAACAACTGTCTTTTTCAGGACTCAATGTAGGCA +AGACGCTATGTAAGGCTTGGTAGATAATTTTTTAAAAAACATAAAATCTAGGTATATATT +AGACATGTGCTAAAGTCTATAACGCCAGCATTATAGTGACTATTTTGGTGTGGTAAAGAC +GAGTTCGTGTTATATTCAGAGAACAAAAAGATCAATTAAGACAAAGGCAATCCTAGAAGG +TTACATGAGTGAAAGCAAAAAACTATAAAAGCATCATGGTGTAGGGGGAAAAACATTAAT +TAGAATAGTCCAAATAATAATATTATCCAATATGTAAGCATTTACTATTTTTTAGGCATT +GGCCAAGGAGTGTATATGTTATTTCAATATAACACTGAACAACACTCAGAACGACCCTAA +GACACAGACACTATAAATATCTCCACTGTACAGATGAGGAAATGGAGCTTTAAAAAGGTT +AAGTAACTCGCTCAAAGTGATATAATTAGTAAGTGGTAGACAGAATCAGGCAATTTGACT +CCAGAACTTGTTCTCCTAACTACCATGCCGCCCTACCCAGGCTCTAGTTCTAGCTATGCC +ACATAAGAATCTGGTAAACTTAAGTAAATCTTACTTTATCTGATCCTTGTATCCTTCTTA +TATAAAATAGGGATAACAATGTCTGTTCTGTCAACCTAAAAGGTCTGTCATAAGGAACAG +GAGAATATAAGTGATGGAAACTAGAAACACTATTTCAATGTATGATTGGTAAGTCTTATA +AGAAGTTACTGCAATTTTTAGCTTGAGGATTTGTATTTGGTTCTTTTTTAATTTCTATCT +CCTTATTGATATGATCTATTTGGTGAAACACTGTTCTCCTGGTTTCCTTTAGTTCTTTGT +CCATGGTTTCCTTTAGTTCCTTGAGCATATTTAAAACAGCTGATTTAAACTGTCTATTAA +GTCCAATGTCTCAGCTTCCTTGGGGATAGTTACTATTAATATTATTTCCTTGTGAATGCC +CTACTTTCTTGTTTCTTTGCATGTCTTGTAACTTTTTTGTTGAAAACTGGATGTTTTGAA +TATTATAATGTGATGCCACTAGAAATCAAATTCTTTCCCTTATCCAAGGTTTGTTGTTGT +TGCTTGTTTGGGGTTGTAGTTGTTTATTTGGTTTTCTAGAGTATTTTTGTAAAGACCGTA +TTCTTTGTTATGCATGGTCATTGAAATCTCTGTTCAATTAGCTTAGCGGTCAGAAATTTG +ATAGAGATTTCCTTAAAAACCTAGAAACAAAAACAAAACAAAACATATTTTCCTGGTCTT +TACAGATTGGCTTTGAACTGGGGCACTCCTTAAATACTTAGCCAGGCTATTTTCAGTTCT +GCCTTAGTCTTTACTTCCTGCTTATACAGAGCCTACAGATCAGTTAGAGTTAAAAGCTTG +GGGTCTTTTTGTGTATTTTCTGAACATGGGTCTAGCTCTGGATATGTGTGTGGCCTTCTG +GATTTCCCATTTATATATATACATTATATATATATTATATATTTTTATATATATATATAC +AATATATATAATTTTATATATATAAAAAATATATAATATCTATATTATATATTATATATA +TATACTATATATATTGTATATATATACACTATATATTTTTATATATATACTATATATATT +TTTTATATATATACTATATATTTTATATATATATACAATATATATATTTTATATATATAT +ATATATATATACACACAATATATGTATTTTATATATGTAATTTAAGAGATGGGGTTTTGC +TGTCACCCAGGCCAGAATGCAGTGGTATGATCATAGCTCACTACAGTCTCAAATTCCTGG +GCTCAAGCAATCTTCCTGCCTCAGCCTCCCAAGTACCTGAGACTACAGGTACACCACCAC +ACCCAGCAACTTCCAGAGACTTGAATGATTGGTTTTTAAAAATAGTTTTCACCACTTACA +CTTGTTTGCTAGAGACTGGGTCCACAGAGCTCCCTGTGCTGCCATCTCAAAAATGAACCG +TACTCTCACTTACCTTTTTAATTATTTGATTCTATTTCTATTCTTGAGCTTTGCTCTTGG +GTGCAGTTAAATTACTTAAAAACAAGTTGGTCCTTTCAGGTCTTGCTTTTAAGAATTTTG +AGCTGGGCGCGGTGGCTCACGCCTGTAATCCCAGCACCTTGGGAGGCCGAGGCGTGTGGA +TCACCTGAGGTCAGGAGTTTGAGACCACCCTGGTCAACATGGTGAAACCCCGTCTCTACT +AAAAATACAAAAATAAGCCGGGCATGGTGGTGCGGCCTGTAGTCCCAGCTACTCCAGAGG +CTGAGGGCAGGAGAATTGCTTGCTCGAACCCGGGAGGCTGAGGTTGCAGTGAGCCAAGAT +CGTGCCACTGCACTCCAGCCTGGGTAACAGAGTGGGAACTCGTCTCAAAAAAAAAAAAAA +AAAAATTAGAGCACAATGGCTCATGCCTGTTAATTCCAGCACTTTGGGAGGCCAGGAGTT +TGAAAACAGCCTAGGCAACAAAGTGAGGCCCTGTCTCTACAAAAACATGAGAATATTAGC +TGGGCATGGTGGTGCACACCTGTAGTCCCAGTTATTCAGGAGGCTGAGAAAGAAGGATCA +CTTAGGCCCAGGAGTTCGAGGCTGCAATGAGCTATGATCATGCCACTGCACTCCAGCCTG +GGTGACACAGCAAGACCCACCCCGTAACTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAGA +ATTTTTAGTTGTGACCATTGCAACATTTGGGCTAAGGCTATCTGAAGCAAGACCCTTCTG +AGTACCCAATGTTCTGTGCCCCATAGAAGTTTTCCAATCTAGTTGGTGGGACTATTCACA +GCACTGTGTTAGTGCATGATTGCCAGATATTGTTTTCTCTGATCCTTTCAGGTGGTTCTT +TCACTGCCTTGGGTTGTTTCTTCACAAGGATGCACTAATTAGTACTTCACCGAATACTCA +AGAGGGACCCTACACAGTCATCTGGAGTTCCCTCTGTGCGTAGCTCTCTTTTCTCTGGTA +CTCTATCCTGAAAAGTCTAGCTAATTAGGTCTCATTGGATTTCCAGTAGAGACGGGTGAA +ACCCCATCTGTACTAAAAATATAAAATTAGCTGGACGTGGTGGTGGGCACCTGTAATCCC +AGCTACTCGGGAGGCTGAGGCAGGAGAATCACTTGAACCCTGGAGGCAGTGCAGTGAGCC +GAGATCGTGGCATTACACTCCAGCCTGGGCAAAAAGAGCGAAACTCCATCTCAAAAAGAA +AAAGAAATGTCTGCATCCAGTGGACAGGGTGATTTTAGACTCTGAACCAATGTGTGAAAC +ACCTTGGGAATTTTATTTCTAATGAAAATCACATAGAGCCCTGAGTAAAAACAAGATTCT +TTCTGTGCTTTACCTGGATCAACGACAAAAATTTTATATTCCTTTTATCAAGGTTAAGAA +GTCCTTCCAGCCAGGTGTGGTGGCTCACGCCTGTAATCCCAACACTCTGGGAGGCTAAGG +CAGGCAGATCACTTAAGGCCAGGAGTTCAAGACCAGCCTGACTAACATGGCAAAACTCAG +TCTCCACTAAAAATACAAAAATTAGCCAGGCATGGTAGCATGTACCTGTAATCCTAGCTA +CTCAGGAGGCTGAGGCACGAGAATCGCTTGAACCCCAGAGGCAGAGGCTGCAGAACCCCA +GTCTGGCAGACAGAGCAAGACTCTCAAAAAAACAAAAAAAAGAAAAATTCCTTCCAGGGT +CTTGGCTTTATAAAGAGGTTTTAGTTTCAGTACCTATCCCCACCTTGAACAGGGGAGCAG +AGCAGGGTCAAGACCTCATCTTTTTTCCCTTCACAGACATTAAAACTCAAGTTTAGGGTT +TTTTCTGTTTTTGTTTTTGTTTTAGAGACAGGATCACAATTTGTTGCCAAGACTGGCCTC +GAACTCCACCTCAGCCTCCCAAGTAGCTGGGACTACAGGTGCATGACAGCACATCGAGCT +TAAAACCCAAGTTTATAACCAATGAAACTATTTCTGAATCTGAAAATCATCTCCAGGACC +ACTACAACTAGTTTTTAACTTGTTGATCATTTTGGCACATGGTGAGTTCCTTGCTGGGGA +GTTCAGGTAGGTATTAAATTGTTCATATTTAAATTTAACATTTCTAGGTAGTTACAGCAG +AAGGTATTCTATGTTAACTAAGTCTATCATGTTTTGGGACTGTTAGTTTCCCTCCTCCAT +AAGTTTAGGCAAAAGTTTGTATATGTATGCAGATATGCATTATTATGGAAGAAGTCCATA +ACTTCAATCAAATTCTCAAATGGGTCTCTGACCCAAACAAAGGTTAAAGAGAATTGCTTT +TAACCTTTGATTCATTTGCCTAAAATTTTACAATTTAGATGCTATTTCTACAAATCCAGG +AATTCTTTGAACTTACTTTCCCTACAATATATCTGAGTGTATTTTCCATATATTTCAAGA +TAGTAAATCCCCATTTGTCTTCATATCTTTTCTTTATCCCTACTTACATAGATTTTAAAC +ACATTTTTTACCCAATGGCCAACAGAATGAAGATACTATGTATCTCCCTTGAATGTGAAA +GCCCAATATACTGCAAGAAGAAGGAAGAGGAAGGGGTAGGGAGAAAAGAACTAGTCTGAA +GAATTAATGTAGTACACAGAAAGAGAGCATTTTGACAAACACAATATGATGATGGTTAAG +ATCTGAAGGCAGGAATAAGATGTTAGCCCCAGAGAGGGGGAGCAGCACTTCTGAGTGTCC +ATCTGTTTTGTAAAATGACTCCTTGATTAAACCACCTAGCCTACTTGATTTTTACTCTAC +ATACACAGGGCAAAGTGAACTGCGTAGCGAAAAGAAACACTTTTTGGTTTTTTGAGACAT +GGTCTCACTCTGGTGCCCAGGTTGGAGTGCAGTGGCATGATCTTGGCTCACTGCAGCCTT +CACCTCCCAGGCTCAAGTGATCCTCCCACCTTAGCTTCCTGAGTAGCTGGGACTACAGGC +ACATGCCACCACGACCAGCTAATTAAAAAAATTTTGGGGGTAGAGACAAGGTCTCACTAA +ATTGCCCAGGCTGGTCTCAAACTCCTGGGCCCAACAGATTCTCTCTCCTTGGCCTCCCAA +AGTGTGTTGGGATTACAGGCGTGAGCCACCACGCCCAGCCAAAATTTTTAATAGTGAATA +ATCATAAATATATACATATATACACAAAATATGTATATATAAGTATATCTCAAATGTCCA +TTACAATTCTAACATTGAAATAGTTGGAAAATTCCACATATAAATAACTAGAGTAGGAAG +GAAATATATATATAGTTTCACTCTTGTTGCCCAGGCTGGAGTGCAGGGGTGTGATCTTGG +TTCACTGCAACCTCTGCCTCCCAAGTTCAAGCGATTCTCCTGCCTCAAGCTCCCGAATAG +CTGGGATTACAGGTGCCCACCACCACACTTGGCTAATTTTTGTATTTTTAGTAGAGACAG +GGTTTCATCATGTTCACCAGGCTGGTCTCAAACACCTGACCTCAGGTGATCTGCCCGCCT +CGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACTGCATCTGCCCAGAAATATTCC +TTACAGAAAATTCCATTATCAGTTGGGAGAAGAGAAAAATTGAGAGAGAATCAATTAATT +TTGGCATTTAGGGTTTACTGAAATATACTATCTAGACAGTCATAAATAGATTATTTCCTT +GGGGAAATTATCATCAGACACATACAGGTAGAGTCAGAAAAACAACTGAAAAATATTATA +ATTGATAAGGCTAGTCTTCTTTTCTAAAAAACTATGCATAGCTTAATGTTTATAGTTGAC +ATACTGCTCTGACATTCTTAAATGAAATAAAATTCAGTATAATAGCTAGTCACTTCATTT +GGTTCTTCCAATAGCATTATTATTAATTAGCAGTAATAGTATTAACAAAAAAGGTAGTTT +CTGTCTTCCAAGAACTTACTTTTGGGTGGGAGCAGTGGCTCATGCCTATAATCCCAGTAG +TTTGGGAGGCTGAGGCAGGTGGATCACCTGAGGTCAGGAGTTCGAGACCAGCCTGACCAA +TATGGTGAAACCCCATCTCTACTAAAAATACAAAAATTAGCCGGGTGTGGTGATAGGCAC +CTGTGGTCCCAGCTACTCGGGAGGCTGAGATAGGAGAATTGCTTGAACCTGGAAGGCAGA +GGTTGCAGTGAGCCAAGATTGCGCCACTGCACTCCAGCCTGGGTGACAGAGCAAGACTCT +GTCTCAAAAAAAAAACAAAAACAAAAACAAAGAACTTACTTTCAAGAGCTTCCTTTTAAA +ATGTTCCTTAAAGTGTCAGATAATTTATACATTAACAGTCAAATCTTACAAGCCTTGTCC +CAAATAAATAAGATAGACTTCTATGATTTAATCTATGTAATATGTAAGGAAAATTACCTG +CCCCAATGTCCACTTGACTATGTGAGGTTTTTATTCAAAATATATTTTTTCCATATGATT +CTCTGCTAGCAACTAACAGCTGCCAATCAAGAGGAGCTGTCATAAAAGAAGTCTTACTGA +TATAGTAAAAAAGACAAATATGAAATTCAAAATCAATCAAACCTGAATTTGACTATTGGC +TCTGCCACTGTACAACCTTGATGAGGCTATTTACTAATCCATTTATTTAACTGAAAAAGT +AGGGGAATATTATACCCAAGTCACAGGATTGTTATAAAAACTACGTGTAAAAATTCTTAG +CTCTCAAAACACTAAAAAGAAGAAAAATGCAACAAACAAAAAAGTAGTAACAGCTAGAGT +GAGACTGTGGTACACAGCCCATTGTAATTGACTCTTCTTCACCTATCCTGTGAGTAAATA +GGGTCCAAGCATTTCCCATATTACAAAATTAATTATGTAGCAGATACAATTTTCCACAAT +TTTTGTTATAGGCCTCAAGATTCTAACTAAGGCCAAGTGTTCTCAAATTTACTCATTCAT +TAAATTCAATCTACACCCTTCATATTCTTCTTATATGTAGGAAACATTTTATAAAATTCT +CCAAAATTCCTGTAAAATCCTAGATCCTAGCAGATAGCAATGAAAAGAGATTATCAACCT +CCCCGGCCTTAAATTAAAAGTCTCTTGAGGTTTGATCCCTTGAACTAAAATACTTATTAA +GGCTGCAAAAGATAAAAAGATTCTACATAAAACAAAACAAACCCTAGATGACAAAAATCT +TCCTTTCTCCTGATCTAATCCTCTGGTCCCACTTTCTTCCAGTCCTGAGCTAAGGGCCCA +AAAGCAAGCAATTGATTATAAATTGAAGCAACATAATATATACCTCAAAAGTTGTTTCTA +TTGAGGTGTAGGTATACCCTAATGGGAAGTAGATTTACTTGCTAAGTAAGAAACAATAAA +AGATTGGTGTTAGACAGTTTAATACTCCCGTCTCAACAGAAACCATCTTTGTCTACACAT +TTAACAGTAATTGAAAAGTAAAGGCTAGGCCGGGAATGGTGGTTCACGCATGTAATCCCA +GCACCTTGGGAGGCCGAGATGGGCAGATTATCTGAGGTCGGGAGTTCAAGACCAGCCTGA +CCAACATGGAGAAACCCCATCTCTATTAAAAACACACAAAAAAAATTAGCCAGGCGTGGT +GACGCATGCCTGTAATCCCAACTACTCAGGAGGCTGAGGCAGGAGAATCGCTTGAACCCG +GGAGGCGGAGGCTGTGGTGAGCCAAGATCGCGCCATTGCACTCCAGCCTGGGCAACAAGA +GCAAAACTCCGCCTCAAAAAAAAAAAAAAAAAAAAAAATGGAAAGCAGAGGCTAATACCA +CTCTATCAAAATACTTCCAAGGGAGTTAAATTTCTATCATTCCAAAATGAAGTTACACAT +TTGTTTTCCCTAGATACTTCCCTATGAAAATGAATTCCTTTATTGGTAATTTATGTGGGA +AATTTTCTAATTTGGTAAAAAGGGCACAAAGAGGTAGTATAACTTTGGTCTAGTCATTTA +ACCTAGGTAAATAAACAATTTTTCACGTAGACCAAGTGCCCTCCTCTATACCCTTGCTAT +TCAAAGTGTGGTCCGTAAACCAGCAGAATTGGCAATCACTTGGGAGCTTGCTAGAAATGC +CAAATATCAGGCGTACTATACTCCCATATAGGATACTACTAAACCCCAGACCCAATGAAT +CAGAATCTGCATTTTTAACAAAATACCACGATTTATATACACAATAAAGTTTGAGATGCA +CCCCCTCTATACAATAAGTACACCTCAATACATTTGACTAAATGATCTTAAGGTCCCTTA +TAGTTATTTTGCATGAAAAATTATATCCAACATTAAAGCCTATATTCTTGTTCTTTTTTT +TTTTGAGATGGTCACCCAGGCTGCAGTGAAGTTGGTGTGATCTCAGCTCACTGCAACCTC +CGCCTCCCAGGTTCAAGTGATTCCCCTGCTTCAGCCTCCTGAGTAGCTGGGATCACAGGC +ACGTGCCACCACGCCTGGCTAATTTTTGTATTTTTAGTAGAGACAGAGTTTTACCATGTT +GACCAGGCTGGTCTCAAACTCCTGACCTCGAGTTACCCACCCACCTTGGCCTCCCAAAGT +GCTGGAATTACAGGCATGAGCCACTGCCTGAAGCCTATATTCTTATGTAACAAGAGTCAG +CTGGAGCTGAGTTAGAGCTGCACTCTCCCTAGCTACCCCAGTCCTCACCTGGCCCTCTCC +ATCTATTTATGTTAACTGCTTGGCTCCTAGTCAGCAGAATTGAAGAAGTCTGCTTTTCAG +TATTTAAAAACAAATAAACAAAAAAATGTTGTCACAGGTAAAAACTCATTAGCTGAATGT +TTAGGTAAAAGGAAAAAAAATGTTAATTTACCTTGATGGGAAGTAGTGAGGTCCGGGTAG +GAAGTAAGGGTGATGAAAAGAGAATCTTGGTGGTGTCCCGAACAGTGTGGCTGGATGGCC +AAGGGGAGGGGGCTGGTAGACATGTGGGTGTGGAATGGGAGAAGCCTGGGGGATTGGAGC +ACTTCTGGGACAAGGGGAAACGCTGGAATACTCCCTAGGAGGTTGGATGGTCGAAGTTGC +AAATCTGGCATGGGCAGTACTTGCACTACTTGAAATCCTGTTGGCGCTCTCTAGAGAGAC +AGGAGTGGGTTGCTTCACAGTGTGAGTGGCTTCAGAATGCAGCTGATGAGTGTCTGTTTG +GGAAGGCCCAGTAAAGCGTTGGGGTGGGAGTGCTGGATAGACAGGTAGACTTGGATCCTG +GACAGCCACCTGAGCAGCACTGGAGACGCTGGGCTGGAAAAGTGTGACAGGGCTTGGGCT +CTGGACTGCAGGTGTGGGCAGCTGGATAGCAGGTGAGGTTTCACCTTTAGAAATAAAAAT +AGCATAAATCAAGAATTAACTGAGTCATTCCATGTTTTTCTTCTTTCAGTAAAGTTTAAT +AAATTGTATAAGCAGAGGCCTTCATCAATCACCTTACCTAACTGCATCATCATATCAAAC +CACTCTATTTCATTTGCAGCATTTTGAACAAACTGAAGTTATCTTGTTTTCTTGTTCATT +TACATTTTTTGTCTCTCTCTCTCAACTAGACTCTAAGTGCCATGAGAAGAGCAACGTTTT +CTGTTTCGTTTGCTGCTGTATCCCCAGGGTGAAACATTCTGTCTGGGGCAGAAGAGGCCC +TCAACAAATATTTTTTAGATGAATAAACAAATGAATAAAATTATTGATAGATATATTAAA +AGACTGAAAACACATAAATGCTGGTATGCATATATACATTTAAAAATAATAATAATATGA +AGCTATTGACACTAGTTACCTTTAAGGAGCCATGATCTAAGAGAGGGGACAGGGCAGTGG +GGCAGGAGGAAAAGCCAGACTTTCGTTTTATACCTACTGGTACTATCTGAATGTTCTGTT +TACCTAAATATATTAATCTTATTTTTAATATTACTAGGGGTTTCAGAGTAGCAGTATGGG +TCATTTTTCTTTTCTTTTATAAACTTCTCTATATTAAACTAAATTATAAATGACATTTAA +TTTTTTTCGTTGAAAAAAACTTAAACAACAAAATTACTTCACTCTATTGTATTCAATATG +AATACGAAAGGAAATTTCCAAGTGAGAACAGGACTTGCCACATGTCAACCACTGGTGACA +GATACAAAAGGAATACTATTGCAGCAGAGCATGAAAGATATGGCAAAATTTTTAAAGGTA +GGTGAAACAATTAATGTGTTTTAGCTTTCTGTTCTGAAGAAGACAGGACTACTGATTGAG +CTGCTAAGTGACCCAAATGACACACCTGGTCTAAATTTAATTCAACTTTCCTGAAGAAAT +ACAGATGGATGCCACAGCAAGAGAGTCATGATCTAACGTATTGCAATACAGTTTCGAATC +CATTAATAAAGAAGATGCAGTCCAAGAAATTCTGCGGTTGGACATGTCTCTGTCATAGAC +TGAAAGAAATGTGGATCTTTTCCCAGCCTCATTCAGGTGACTTCCCTCTCCTTTCTTTTC +TCCAGATAAAGCAGATAATGCCCCTCTTAAAGCAGGAAGTAGGGAATTAAGGGACATAGC +CACCTGTCTGAAGATGGGCTCTGACCCAGTGAAGTAGAGAAACAGGATGTAATGATGCTG +CCCTGATTTTCACCTGATGAGGTTATCTGGACTAGCCCCACTATCTGTGAGGCACAGGCC +CTACTCAGGCCCTTCCTGATTTATCAAGCATAGGTTAATTTCCCTTGTCCACGTTCCCTC +CAAACCTTGTAAACCTATCACCTATCATGAAATAGTGTAAATCTTTGTGATTATTTGCAT +GTCTGCCACCCCAACCATGATCACCAAACTGGGAGATTGAGAGCAGGAACTCTCAATTTC +TATTCGTATCCCAGTATCTAGCCAGAACCTGGTTAATAAAAAATAGTTAAGAAAAGTATG +AATGGATACAGCTTTATAAAAGTTCCAAAGCCTTTAAATGAATAGGAATACTCATATAAA +AGGAGGATGCTGGCATAACTGGCATCAAAGACATGTAATCAAAGATCTGAAGAGAATTCC +ACACTACCATGCTATAAGCGAGACAGGGTAGTGGGGTGGCGGGGATCATCTCACCTTCAC +TCACGTATTTTTCCATACATGCGCACTGACCACCAGACCTTGCAGCACCACCCCCACTGA +CACCATACCCATTGACCAGACCTTGCAAGCTGTCTGAAAAAACTAAGATAAGCAGCATTC +CACCACAAATCTTACTCAAGGGAATTAACTCTATCGCCTGCATGTGCACAAGGGCTGCAT +GTGAGAATGGCCTCCTGGCAAATTCTAGAATGACGATCTAGAATTAGAATGACGATCCTA +ACCCCTAGGATTGTAATATTAAAATCTCTAGGATTGAAATACTAAAATCTCCGCCCAGGG +AGATTTTCTGATCATGATCAACATATGAGTTAGCATGATTCCTTACTTGTCTGCACACCC +TGCACTCCACCTCGCATATGTAATGACACTCAGCTACCTCATGCATTATGCATATCACCC +TCCTGAAGACACCATAATGCACTCCCTTGGAGAGCCAGCCAGAGAACCCTTTCTCCTGTG +CTGTCTCTCTTAATACCCAATCTTTCCAGGCATAAGCCCTAACAACCCCTGTCTAGGAAA +AGTTTGCCTGGCCTCTTGTTAATTTCTATTACACTGAGAGCCAAGAACTTTACGCCAGTA +ACATAAGCACTTTCAGAAACTAGAAACAGGGTGGGTGCCATGGCTCACATTTGTAATCCC +AACACTTTGGAAGGCCAAGATGGGAGAATCACTTGAGTCCAGGAGTTTGAGACTAGACTG +GGCAACCTAGCAAGATCCCATCTCTACAGAAAAAAAAAAAGAACTAGTAAGAGAAGAGGA +GCTTGGGAGATAGTACTAAATGTGAGTGACAGAGTAAATAATGCACCAGACATAAAAATA +ATACCAGACAAGTGCTGGGCGTGGTGGCTTATGCCTGTAATCCCAGCACTTTGGGAGGCC +GAGGCAGGTAGATCGACTGAGGTCAGAGGTTCAAAACCAGCCTGGCCAACATGGTAAAAC +CCCATCTCTACTAAAAATACAAAAATTAGCCGGGCTTGGTGGCATGCACCTGTAATCCCA +GCTACTCTGGAGGCTGAGGCAGGAGAATTGCTTAAACCTGGTAGGTGGAGGTTGCAGTGA +GCTGAGATCATGCCACTGCACTCCAACCTGGGTGACAGAGCAAGACTCTATCTCAAAAAA +TAATAATAATACCAGACAAGAAAGTAGATTCTATCAAAGAAATAGTAAAAGTAGTTATAT +TTATATCTATACTTGCTACGACTACCTAACGAACTCTTTGACAGCAGAGACTACAAAAAA +ACTTTATATGTTGTTCCTAGCAGAGTTTGCCCCATAATAGGATTTAAGAAACCTTAGTAG +TGAAGGCGGCAGGTAAGCAGGCAAACAAATGTGCCACTGGAATTTACTCAGAAGATATCT +GAGATAAAACTCACTGTTACAGGGGAGAATACCAGATTAAACTGCCAGATTTCGAATATA +TTTACTGAATATCTTAATGTGATAAAAGTGTACTGGGAAGATCTAGTACAGGACAAGTGA +TCGATTAGAACAAAAAGGTTTGGTAGAATACACAGTAAAATGAAATCAGCTTGAGGGCCG +GGTGCAGTGGCTCATGCCTGTAATCCCTGCACTTCGGGAGGCTGAGACGGGCAGATTACT +TGAGTCCAGGAGTTCAAGACCAGCCTGGCCAATGTTGCGAAACCCCGTCTCTACTAAAAA +TACAAAAATTAGCCAGGCGTGGTGGCGCTTGCCTGTAGTCCCAGCTATTCAGGAGGCTGA +GGCAGGAGAATCGCTTGAACCTGGGAGGTGGAGGTTGCAGGGAACCAAGATCACGCCACT +GCACTCCAGCCTGGGAGACAGAGTAAGATTCCCTCTCAAAAAAAAAAAAAAAGAAGAAGC +TTGATTGAGAGCCAAATAATGGAGAAATATTACTAGAAAATCCATGAATTCAGTGTGTGA +AATATTATGCGGTAGTAATCACAACATATTTAAATTTATGATCCTGGCTAAAGAGAAAGT +CAAAAAAATCTACGCTGGGGTTATTCAATTTTTGGAATATTGATATTGGCTAGGGAAAAA +GGCTGATAGAGATTAAAATAAAAAGTTCATAGAAAAATGGAGATTATTTTACATGACAAT +GCTAAAAACACAAAAGAAAGAAATGTGCCTCAAAGTCACAGTTACTATGGCTAACTGGCA +AAAAAATAAATAAATAAAAAATAACAAAAATAACAACAACAACAACAACAAAACCTTCAA +AAGCTTGTCCAAATGTACAAATGAGCCCAACTGCGGTGAGGCAAATGCAAAAAAACTAGG +CAGTCCAAAGGAAAATTGAAGGAGCCACACCTGAGAGACCTCAAAGTCAATACTAATTGA +CTCCAAATATTTTTACAAAAAGGAGAGAATCGGTGGAATTATTTAGTCATTACGGTATAA +ACAGCAACTGACAGAGAACAGAGAGACTCAATAAATTCCTTTCTCCTAAAGAAGACCTTA +AGATTTCTGAACCCTAATTTTCAAAGTAAATAGGTTAAAAATATTAGATCAACTACAGTA +TAATGACAAGTTCAAAGAATGTTCTAATCCAATTGACAAAAGGAATATAAATAGATCTTA +GATGGCATTCACCCAAGAATTTTTTTTTTAAAGAAGAAAACGGACAACAACAACAACAAC +AACAACAACAACAACAAACCTCTGTCCAGGCATGATGGCTCACACCTGCAATCTCAGCAC +TTTGGGAGGCAGAGGTGGGCAGATCACCTGAGGTCAGGAGTTTGAAAAACCAGCCTGGCT +ATCATGGTGAAACCCTACTAAAACTACAAAAATTAGCCAGACATGGTGGTGCATGCCTAT +AATCCCAGCTACTCGGGAGGCTCAGGCAGGAAAATCACTTGAACCCCGGAGGTGGAGGTT +GCAGTGAGCTGAGGTCGCGCCACTGCACTCCAGCGTGGGCAACAGAATGAGACTTTGTCT +CAAAAATATATATAAATATAAATATTAAAAAATTTTTTTAAAAAACCTCAAGGGTGGAAC +TGAGAAAATTTTAGACAAAGTAGGTACAAATGGCTTCTGCCAGAGATTTTTAGAAAATTA +ACATGACTTCCAGCTATTGAAACTGATGACCTTGACAACTCTAGCTTGGTGAGTCTATTA +TCTACACCTGAAATGGTGGTGAAATGTATACAGTACGATATTAATGCACAAAGCTTGCTA +CAGAAAAAGAGCAAATTGTTTTTATATGAGAAAAATCATATACCTCACTATCTTGATATC +TTTCTTCCATGGAAATACAGCAAACATGCTTGAAAAACAAAATTACCGTAACTTCATATT +TAGAATATGAAATTACTTGAAACAACAAAAAAGTATATACATTAACAACTGTATATGACA +AGATATTAAAATTATGATTCCCCAAGATTATAGCACACGAGATGTGTGCTATAATCTGTT +CTAACTTAAGCTTCACAAATGATTTAGAATATTAAATATACAGTGAAATTTCCAAATTTG +CAAGTGATACTGACCTCTCTAAATAATATAAAGCCAAGTTGATGAGAACAATCTATAAGA +ATATATTTCAAAGCCATATGATTGGGGAACAAAATAGCAGATAAATTTCATGATTTACTG +TTAAGGTGTATATCTTAATAATTCCCAAATTATGCTTATAAGATAATGTTCTCTGTTTAT +CTTTTGAGATGCAAGAAACAAATTTGTTTGTTTGTTTTTAGAGACAGCGTCTTGCTATGT +TGCCCAGGCTAGTCTCGAACTCCTAGGCTCCCAAAGCACCAGGATTACAGGCATGAGTCA +CCACAGCTGGCCCAAGAAATAAATCTTTACTGACACTACATGTCACCAGAAATAAGAGAT +ATTGTAAAAAACAAAACAAAAAACTAAGCACAAACAAAAAAATCATTCTTGTCTTAGATT +TGATTACTGTTGTGCATAGCTCTGAAGTGCTTCCTATAATTCTGCCTACCATACTTAAAT +ACAACATCATGGAGAAAGAACCCTACCAACATTAGAAGAAATCTTCCAGTTTCTACTAAA +CCCTTATCTTTGCTCAGAATGGCATAAAATTAATGTATCAAATGTCAACTGTTTCAAATA +AGAACGTTGTTAATTCTGTTTCTGGGAAGAGAAAATATACAGCATTTAACAGTGGGTAGA +AGCAGATGTAAGTGAGGTCTTGGAAAAAGGGATAAAAAGAAGAAAATTATATTATGAAAA +CAGAAATCATAACATAACACAGGCTGGGCATGGTGGCTCACCCTGTAATCCCAGCACTTT +GGGAAGCCAAGATGGGTGGATCACTTGAGGCCAGGAGTTCGAGACAAGCCTGGCTAACAT +GGTGAAACCCCATCTCTACTAAAAATACAAAAATTAGATGGGCATGGTGGTGTGCACCTG +TAGTCTCAGCTACTCGGGAGGCTGAGGTGGGAGAACTGCTTGAACCCAGGCGTCAGAGGC +TGCAGTGAGCCGAGATCGCGCCACTACACTCCATCTTGGGTAACGGAGCAAGACTCTGTC +TTAAAAAATAAATAAATAACATAACAGAAAAACAAGGTAAGTGAACAAAGTCATAATTAA +GCCTGGGTTGAAATACAAGATTAAAGAAGTCACTACCAAACAGTGAAGACTGAGAGTGCC +TGCCTGTGCTAGGACAGAACAGGGCTATAGGATCAGCTTTCTGCATCTCTCTCTTGAGTC +TAGACATCTGGAATGTAGCTTGTTGCTATCAATTGCTAAAATGATACATTAAAAAACAAC +AACAACAACAACACTGAAAATGCCTAAGATTCTAAGAAGTCAGTTTCCAAGGTATCTAAA +ACTCTCAGCTCATATGGGTGGCTTTATTACCAGAAGGATTTAAAGAGGTTAAAAAAAAAT +AGAAAAAGCAGGTTTACGCAGTCTTAGTAGGTTTAAGAAAGTGGGCCAGATATGGTGGTT +CACACTTATAATCCTGGCACTTTGAGAGGTCAAGGTGGGTGGATCATTTGAGCCCAGGAT +TCGACACCAGCCTGGGCAACATGGCAAAACCCCATCTCTAAAAAAATACAAAAATTAGCC +AGGCATGGTGGTGTGCACCTATAGTCCCAGCTACTAGGGAGCCTGAGGTGGGAGAATCAC +TTGAGCCCAGGAGGGCAAGGCTGCAGTGACCTGTGATGCTGCCACTGCACTCCAGCCTGG +GCAACAGAGTGAGACCCTGTCTGGAAAAAAAAAAAAAAAGTGACAGCAAGTAGTGAATGT +ATAAAGCTCTCCCTTAAAGATGGTTAAAACATGTTCTGGGGGCCAGGCGTGGTGGCTCAC +ACCTGTAATCCCAGCAGTTTGGGAGGCCGGGGCGGGCAGATCATCTGAGGTCGGGAGTTC +CAGACCAGCCTGACCAACATGGAGAAACCCCATCTCTACTAAAAATACAAAATTAGCCGG +GTGTGATGGTGCATCCCTGTAATCCCAGCTAGTCGGGAGGCTGAGGCAGCAGAATTGCTT +GAACCCAGGAAGCGGAGGTTGTGGTGAGCTGAGATTGCACCATTGCTCCAGCCTGGTCAA +CAAGAGCGAAAACTCCATCTCAAAAAAAAAAAAACTGTTCTGGAAAAACAAACCAATGAT +GGATAGCCCTATAACAAGTTATTAAGATATTAGGTTGTCAATTTTTGGTTCTTAAAATCA +GTAACAGGAATGTAAAGAACTCAGAGGAGACATTTAGAGAGATTAATATAATGAACCAAA +CAAATATTTGGTAGAAAATAGATTACTTCCACTGCTTTTCTAGAGCAGTGAGAGAATGGT +CTCAACAAATCAGTATCATTACTAAGTTCCAGGACAGGATGCCTCATACCCCATTAGCAA +GGCAGTCTTTTATGCTGTTAGTAAAAAGACTCTCCTTTTTCCTATTGAATTACCTCAGTT +ATTTCCTGCATTATCTGCCTAATCTATGGGCTCATCCTGATTTGCTTAAAAGGTCTGAGG +TTTTACACATGGATTATTTGCTACTCTGGCAAACCAAGTGTTTTGATCTCTACTGAAATT +TTTCCTTCTCCTATTTAATGTTCTCACTTTCCCTCTTCTTTTTTTCTTAACATTGTTGTT +CCAAATTCTTAAGACTAACAGAAAGAACACTTCAAACTTGAGGTAAAATTTTCTTGCAGC +TATTTAAAAAATAGTAATCTACAATAAAACTAACTCACCAACTGGATGAGTGATGGGATT +CTGTAGGCTGGGAATTACCACAGAGTACGTAGGTGAGCGGTAAGGATAAACTGTTGTAGG +ATTTGTAGAGATGATATTCTGTGTGGTACCAGAAAATACATTGGAAACACTTAGAGGGAA +TCGTTTTCGCTTCCCTGGACGAGGCTGATAAACCCAACCTATAGAAGACAAAATATGTTT +AAATGTGTAGACTCCATTTAGCCTTTAAATAATTTTTTTCATACTAAAATGCAAAGCACT +TTAAAGTGTTTTAAAAACAAATTATTGTCTAAAGTATCTTTTCCAGCTCCGGGATATTAT +TTCAGTGAATGACTTCTCCACTGTGTATTTTAACATACATATCCAAATAGCTCCTGACTA +GTGGCCAATGTTATAACTCATCATTGAAAAGAAGAGGGTCAAATTTTTTTTTTTTTTTTT +TGAGACGGAGTCTTGCACTGTTGCCCGGGCTGGAGTGCAATGGCACAATCTCGGCTCACT +GCAACCTCCGCCTCCCAGGTTCATGTGATTCTCCTGCCTCAGCCTCCTGAGCAGCTGGGA +TTACAGGTGCATGCCACCACACCCGGCTAATTTTTTGTATTTTTAGTAGAGACGGGGTTT +CTCCGTGTTGGCCAGACTGGTCTTGAACTCCTGACCTCGTGATCCGCCCGTCTCGGCCTC +CCAAAGGCTGGGATTACAGGCGAGAGCCACTGCGCCTGGCCAAGGGTCAAATGTTTTATA +ACCAATGACACAGAATGAACCTGTAGTAGAGTCAACATCAAAACCGCTGTATTTGAATCC +CAAAGCCTTTCCTCCACCTTATCAAATAATGCCTCACTATGACATTATTCATCTCATTTC +CTCACTTTCTGTAAGTTACAATCATCTATATCTTACAATGCAATAGTCACTAATGATCAG +TCACTATTTTTTTTGAGACAGAGTCTCACTCTGCCGCCCAGGCTGGAGTGCAGTGGCACG +ATCTCGGCTCACTGCAAGCTCCACCTCCTGGGTTCATGCCATTCTCCTGCCTGAGCCTCC +CAAGTAGCTGGGACTACAGGTGCCCAACACCATGCCCAGCTAATTTTTTTATTTTTTTTT +TTAGTAGAGATGGGGTTTCACTGTGTTAGCCAGGATGGTCTTGATCTCCTGACCTCGTGA +TCCACCCACCTTGGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACCGCGCCTGGCT +GATCAGTCACTAATTTTGTGCCTAGTTCAAGAAGAGTCACTCTCCTAAACTCAGCAATCT +CCAAGTCCACAAATAACTTAATTTCTTCCAAAGTCAGAACAGTGGAACTATGGCATTTGC +AGCCACTGTGTAATCAGAACAATCACTGGTTCACTGTAGTTGCTGCCTCTGACCTTCATT +ACTAGAACCTCTCTGCCAATATTTCAGAAAATAATAAGTTTTGTCCCACCTTGCACAGAC +ATGCTGGCCATGCACTGTGCATTTTCCAAGCTTAATCCCAATGTTCCCACTGCTAGGGAG +AAATCGGACTCCTTTCACACTATATCATGACAGGGCTAAATCTATCAATCAGAAGGCAGG +ACTATGTTCTGACAATCATATGTTAAAATGGAATATGGTGACAATCCCTGCATTCTCATT +AAGCGTAGACTGCATTTTTTTTCTGTTGCTATCATTTTAACACTTCTATAGTTTACTTGC +AAAATTATAGCCTAAAGCTTTCAAGATGTACTTTCATTAAACTTACATCTATCTAAATCA +AAACCACAATAAAACTGCGTGTCCTCTGATTTGTATGAGTTGGTGAATATGAAATCAGAT +ATCCCTTTGCTTGGTTCTATTTAAGGAAACTCATGCCCAGTGTCATTTCAATCATTGTTA +TAATATTAGTCATTATTCTCTTTATTGTACATATCAGAAAAAAATTATATATTTTTGTCT +TTCAATCTCAACCTACCCTAATCTTTAACTAAATAAATTCATTTAAAAGAAGTAAGAGGC +ATTATTTAATTTGATTACCAGGAAATTCCTCTCTGTGCTTTTCCTTAATCTTTTGTGCTT +CATCGTAATAGGGTTTCTTTTGTTCTTCACTAAGTTTGTTCCACTCTAACCCAAGCTGGA +CACTGATTTCTGCATTGTTGGCTGCTGGGTTAGCTTTGGCTAGTGCTGGTCGGTGGATCC +TTGCCCAAACCATAAATGCGTTCATGGGTCGCTTCACATGACCATTTCTGTCCTTACTGA +AGGGAGTATCTGGTATGCCTACATGACAAAAATTAAAAGGCTAAATTAATGTGCCATACA +CACACACACACACAATTTTAAGGTAAAGTGCACCTCCGTCTATACTTATTTTTGAAATAT +CTGGAGGAAATATACACTTCAATATAACCAAAAAAACCTGCCAGTATTCCACAATTCCTT +ACATCCCCTGAACTCATCATTCTGAACTGTAGTTTAGAATGACTCCTTTTCCTCAAAGAG +GATAATATTGTTGAAGATAACTGTGGCAATAATCATGTTGAAGAGAGTAAATTGTTGGCT +TATTACTTCTTTGATCTGTATTATTAGTACCTCTAACAATAATTAACATTTATTTATTTA +CTACTAAAAATATTCTACCATTAAGGAACAGGAACCATGCATGACTTACTCGTGACTATA +ATCTTAGCTAGGTAGAGGTTCTCTAAACATTCACAGGAACTCATCTACATGCTGCTCTTG +TGTCCTTTCAAGCAAAACTATTTATAATATTGTAATACTATATTAGTTGTATTTCACTAC +GAAGGTGAAGCTCTTACCAAGTGGAATCATCAACACTAGTCCTGTGTCCTGGGAGAAAAA +TGAAAGAAAACAATAAAAATAATTTTTTGGGCCAGGTACGGTGGCTCACGCCTGTAATCC +CAGCACTTTGGGAGGCCAAGGCAGGTGGATCACGCGAGGTCAGGAGTTTGAGACCAGCCT +GGCCAACATGATGAAACCCCATCTCTACTGAAAATACAAAAATTAGCCAGGCGTGGTTGC +TCATGCCTGTAGTCCCAGCTACCTAGGAGGCTGAGGCAGGAGAATCGCTTGAACCCAGGA +GGTGGAGGTTGCAGCGAGCTGAGATCACGCCACGGTACTCCAGACTGGGCAACAGAGTGA +GACTCAGTCTCAAAAAAATAATTTTTTGAAAGTCACAGAAGGCAGGTAAAATGGCTCACA +CTTGCTTCTGACCTTCATTCCTAGAACCTCTCTGCCAATATTTCAGAAAAAAAATGACAG +AAAATAATAAAAGTAATTTTTTTGAAAGTCAGAGAAGGCAGCCACAATGGCTCACACCTG +TAACCTCAGTACTTTGGGAGGCCAAGGCGGAGGACTGCTTCATCCCAGGAGTTCGAGACC +AGCATCTCTTTTTCATAAAATAAAATTTAAAAAAAGAAAGTCACAGAGCCAGTTGAAATT +TCAACAAAGGAAGTTATCTAAATTCACATCTCTCATGTATTTTATCAAAAATAACTGTCC +ATAAATTTATTATATTATTTTAGGATTACTTCATATATTAAAAATTTCTTAAAAACACTA +AAGATGAAATAAGTAGTATAAAGAAAGCTTTCCCTTTCTTTCCTTTAGAAAACAAAAATA +AAATCTAAAAACTACTAAAGATAAAAGCAACAGGGTGGAGTGGAGAGGAAGAATCAACAC +AGAAAATTAAAAAAACAATAAAACATAAAGTTAATAAAAATATGAACCAAAGATTAATAT +GACTTTCCAAGATGTTCATTGGCAAAGTGTTCTGTGTGAACTAAATCTTAAAATAAGAAT +TTGCTAACTATATATCTGGAAATACTGAATAGAAATAAAAACATTATTTGTACTTGTTAC +TGCTGCAACTAGTCATTTCTTTAAAAATAATATTTATGGCTCATTCTACTGTATTCTTTT +CAATATTTCTATAAGTCATTACCTTTCAGAGGAATAAACCCTAAAATATTACATTGAATC +ACGTATTGTTTTCTGCTAGAATATTTATTATTCATTTTTAAAGATAGCCTCTATAATCGG +TATAAACTTTCCTGTTTAATTATAATCACTTTTTTCATTCAACACCATTATTTCTTCTAT +TTCTTGATACATATAAAAGTACTGAGCTGTTATACTACAATATTTTTAATCTTGATTATT +TGTAGCATATAAACTGAGGGCTATGCGCTGTCTAGCAAGAATATTTCTATTTTTGTGTAC +AAAAATTAGTCCTATCTAAATACTGGGCCTTAAAATCGATTTTTTAAAAAATACTTGAGA +ATCTTGAAGGCATTCGTGTATTTTACTGCTATATGTACAAGTCGATCAGAAGTGATACCT +GTGCAGACTCTGCCCTGAAAACAATCAGTTCCATTACTTTACTTTTGTAGTTTAGACTTG +GGAACTGCTGACAAAACAGCTATGGGCAACACAGACGCAGTTTTGAAAACCCGACTCCCC +TGCTGTCTAATACCTGCATCTGAGGGCAACACGGTGAGCGGGACATCTTTGGTTTCAATT +TTTACAGAAGGCTCCAGTAGGGACTGCATTTTAGTAGGCACTGGTGTCAGGGGGACCTTG +GTCAATCTTATCAGCTCTGAAGGCGGAGCTCCCTGAAACTGGATCCGGGCCCCAGGGGGG +ACCGTGTGGAGCGTCAAAGGGATCCTAAGGTCTTGCTGGTGCGGCCCAAAGGCACCGGAC +GTTGGGGCCAAGATGACCTCCGCGCTGCCATGAACCAGGCCATTGGACGCGGGCTCCGCG +CCGAGCCTGCAGTCCTCGAGGAGTCTCTCGGGTTCCTCCGTTTTGATCACACCTTCTCGG +ATGGCTGCCGGGCTTTTGCCTGCCCCGCCTTGCATCGAGTCTCTCATGACCTCCTCCGCC +TCCAGCTTGCCCTTCTCGTCCCCTCGGAAGTAGCCGAGGGCCGGCCCGGGGCCTTCCAAC +TTGACCACCCTGGAGGCTCTAGGACCGGTTTCGACGGCCCCTCGAGGCCCCACTGACTGA +TCCAGGCTGGGCCCCAGCTTCTGCTTCTTGGCCTTGACATGCAGCGCCAGGGGCTGCACC +GGGTGCAACTCGGGCCTGGAGGTGGCGCCGTCTGACGCTGTCGGCGGCTGCAGGAGCCGC +AGGTCGGGCCTGAACTGCAACAGCCGCGCCTGCGCGGACGAGGCAGCGGCTTCCTCGTTC +TGGGCCTGAGGCTGTGGTAGCAGCAACACCTGCTCTGGCTTCACCTGCAGCAGCCGCCGC +ACCGCGGGCTGTAAGCCGGACGCCACTGCCTCCCCGCACGACGAGGCCAAGGTCGCACTG +GCTGCCGCGCTCAGTGTGGGAGACGACGGAGGGGGCTCCATGGCTGCTGCCCAAAAGGAG +GTGCCCTCGACCGGCAGCGGGGGCGGAGCGGGACGCAACGGGCGCGGCTGAGGCGGCGGC +TCGGGTCTGGCTCTCTCCATGGGGGAGGGGGACGCCCCGGCCAGGATTGTGAGCTCAGCC +GTTTGTTGGCGACCTTCCCCCTCCCCCTTTCGGTTAAGAGCCTTGCAAGGCCTTTGCTAC +CCAGAACCCTACGCGGTTCAAAACGCAGCTGTCTGTCTGGGCCTCACCCAATCACAACGA +CCGATACCCGTGGACGGCCAATCACAGGCGGGTTTTCCGGCTCTTCCTGGTCCCTACTCT +CGCCTCGTGCTGAGTCCTCGAATCACCTGCCATGGTAGGAGCCGCCGCACTTGTTGCACA +TTTTCGTTCTGACTCTCTTGTGGAGTTCTCTTACAGCCGTTGTCTTTAGTCATCCCTCCC +CCACCCGGAGCTGCGACAATGGCGTTGCCCAGGAAACGTTGCGCTTCCAGGCCGCTGACA +TCCAGGGAATGAAGTCTTGCGTCACAAGGGGAGCGACGGCCTTGTGCACGCGCTCTGTGC +GGCCTGAGTAATCTGTCGGCCCTGAGTACCACCAGGGCTTTTGAATCTTTGCCAAGGGAG +AATGGGGAAGATTTTGCAACTTATCAATAACCTATTAGCTAATGTTGCTGGGGAGGATCT +TCGACTTTGTGTGATTATTGTGCTAAAGTTTCAATTAATCACCAGGCCCTGTGGCCCTAC +TTCCAAAATACTATACATCCCAAATTCATCCACTGTTTTGTGTCTCTACCTGCCATTATC +CTGTTCCAGGCTCCCAGCATCTTTCACTGGGATACTGCCGTAACCCTGTAAATAGTCTCC +CTGCTTGTCACCCTTGCCCCACTACACTCCAGCTGCCAGTGATCTTTCGAAAACGCAAAT +CTAAGGTTGTCACACTTTTCCTAAACTTTCCATGGCTCCCCACTGATAATGTAATGAAAG +TCTAAAATTCTTAGCAAAGCCTTAAAAATCCCCCAGTGGCTTGGGATCTAACCTCCTACT +ACTGCTACTATTAGATTGGTGCAAAAGTAATTGTGGTTTTTGCCATTAAATAGTTATTGA +GTCTTTGGGTTTCAGCCACATTGGCCCCATCATCATTCTCTTTCTACTGCAGGGTGTTTA +AACATGCTCAGCATGCTACTCTTTCCTTTGTGTCTCCTTAATTCCTCCTGCACATTTTTC +ATATTGCAGCTCAACTGGGACTTCTTCAGAGAAGCTTTTACTGACTCTGAAAATCAGATA +AAATCTTGGTCTACTTATACCTCTATCACTTGGTTTGCTTACCACAATTTGTAATTAGAA +TTTTCATGTGATGATTCCACTGCCTCTCCCACTTTAGACTATAAAGTCCTTGAAGGCAGA +ACAGTTTGTGTTTTGCCCATCACTGAATCCACAATGCAGACCATTGAGCCTGGCATATAG +TACTCAATAAATACTTGTTGAATAAATAAATGAATAGCGACTGTGATAGGGTAATAATAA +AATAGTAATAATCACTACCTGTGTTAAGGGCTTACTCTTATGCTAGACACTGTTCCAAAT +CCTTTCCATGTTTATGTTTCTCCTTTTAGTAGGATTGTGTTTATTTCCATTAAACATCAC +CAAGAAAAACAAAAAGAAATCCTGTATTAACATTTGCTGCATTTCTAAATGACATTCTGG +CCAAAAACTATAGTTTATCTTGACGTAGATGATTTTTGCAATCAAGACAAGTTATCACTC +AAAGACCACTCCAATTTATTGTCCAATCCTCTGGTAACAAATGTGGTCAGTAGGAGTTCT +TATACCTGGCAGATAGACAAGGGCAATGGTTTTCAAACTTTTATCTCAAGAACTCATTAT +ACCCATAAAAACTATTGAAGATCCTGGGCTGGGCGTGGTGGCTCACTCCTGTAATCCCAG +CACTTTGGGAGGCTGAGGCAGGCGGATCACTTGAGGTCAGGAGTTCGAGACCAGCCTGGC +CAACATGGTGGAACCTCGTCTCTACTAAAAATAAAAAATTAGTTGGGCATGGTGGCACAT +GCCTGTAATTCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCGCTTGAACCTGGGAGGCA +GAGGTTGCAGGAGCCGAGATCGTGCCACTGCACTCCAGCCTGGGCAACAGAGCAAGACCC +TGTCTCAAAAAAAAAAAAAAAAACTATTGAAGATCCCAAAAAAGCTTTTGTTCATGTGGA +TTTCATCTATCAATATTTACCATGTTGTAAATAAAAACAAATTTTAAAGATAGCAACTCA +TTTAAAACGTCAACAATAAAACCATTCTGTGGTAACACATTTTCATAGGAAAAAATTATA +TTTTCCCCACCTTATGCTCACAAGAGAATGAAGTGAAAAGAGCAAATATTACATTAGGAT +TATTATGAAAATAGTTTTAACCTAGCTGACTCTGTAAGTGTCAGTCCCCATACCACACTT +TGAGAACCACTGTACTAGGGTTTAAATGGGAGAGGCAACTGTATGCATGAGCAAAAGCTG +ATAAAAGAGGCAAATAAGTTGTCAGAGGTGTGTGAACCAGAGCACCTCCATCTTGAGTAG +GTGCTGGGTAAAATGAGGCTGAAACATACTGGGTCGCATTCCCAGACAGTTAAGGCATTC +TAAGTCACAGGATGAGATAGGAGGCTGGCACAAAGTACAGGTCATAAAAACCTTGCTGAT +AAAACGGGTTGCAATAAAGAAGCTGGCTAAAACCCACAAAAACCAAGATGGTGATGAGAA +TTACCTCTTGTCATCCTCACTACTACACTCACACTGGCAGCATGACAGCTTACAGATGCC +ACTGCAATGTCAGGAAGTTATCCTATATGGTCTAAAAAGGGGAGGCATGAAAAATCCACC +CCTTGTTTAGCTTATCATCAAGAAATAACCATAAAAATGGGCAACCAGCAGCCCTTGGGG +TTGCTCAGTCTATGGAGTAGCCATTATTTTATTCCTTTACTTTCTTAATAAACTCGCTTT +CACTTTACTTTATGGACTCGCTCTGAATTCTTCCTTGTGCGAGATCCAAGAACCCTCTTT +TGGGGTCTGGATCTGGACCCCTTTCCTGTAACTTCTTTCTGGTGACCCAGGTGGGATTAT +AGTGTGTAAGCCCCCAGTAAGTGGTGAGGTCCTGTAACATCTTTCTGGCAACTATGGAAT +GGACTGCAGTATGGAAACCCCGACCCAAAGGCTAACTTTGGGTAAGTGGTGGGGTCCGGT +AACATCTTTCTGGTGAACCCTAAAGGGACGATACTTAGGAGACTCCTGACTCAAAGGAAA +TAGACTATAGCACTGATTGGACAATTTTGGATAAGTGGTGGGGTACCCAGATAAAGAATG +GGATTGGGTTAGAAGCCCAACTTAGGAGGGTTAGAGTCCCTTCTAAGATTTAGGGGGCTA +GAAGCCCCTCTCGGTAAAGTCCCCTTTGGCTAAGAACAGGTTTGGCACTACGGTATGTTA +ACTTCTATTCTCCTTGGAATAATCTGCCTTGTACTCTTTGCTGATGGATGCGGATGACAG +GGTTAGGCAGGTACAGGATCATGGGACATGAGGAGCTTTTTCCTCCCGTAAAGGGGAAAC +TTGAGAGTCGATGGGACTGCTGGAAAACATCCCTTCACTACCGAGAAGTGGCCACCTGAA +CTCTTCACTGTCGCTGCAGTGGGTGGATCTTTCTGTGGCTTCCCTGAACGCCTGGCCTTC +CCCACCTTGCCTCAGGCAATGCTGTCGTCTCTCTCTGTGCAAACTGGTTGTAGGAATGGT +AAAAATCACTATTTCTTACAAAGTTTTGATTAATGGAAGAAAGGATTTGTGAGGCTAGTC +TTAAGCTGTAGCCAATCTGGTGTGTTTCCTGTGTCATTCTGTATTGTTCTGTCATAAAGA +GGGGTACCTTAGGATAGAACATGGGCTTAGGACACCTATAAGCCTGCTGTTCAAGATGGC +CCAGCAAACTGGTCAGTTAAAAACTTTGCTGCAGGTCCGTGAAAAAAACTGGATGAGGTT +TCCCTCTTGTCTTGTATGTCCTTGGGAGCTTGACCTTGTAACCATGTGGCTGTGCTTTCT +CTTTCACAGTGGTGGCCCGGGTTCAGGGTTCAATTCCCATCTTAGGAGATGAGTCCTTTA +TCTTTTGTCTGTGTATTTATGTGTATCATGTGTGTGGTGCTTGTATATAACAGAGGTTTG +ATTAATCGGTTAAAAATAATAAGTGCTTCAGTCATATTTTTGTGAGAAAAATTAAACATA +TAATGCCTTTTATATAGTTCATGTGACTTAAGTAATCTTTGGGAAATGAAGACAGTTTTA +AAGATTATTGGTAAAATAAAAATATCTTAAAATGTAAACATTTGGTCTAAATTATGCAGG +TCAGATATTAGGTTTGCTAAATGCTTTAAGTTCATAAGCTGCTGCTTTCACTTTTGAAAA +TTGTTTAATTTACCTACTTTGACCATATTAGAGTCTAGATAAGGCCTGGGGACATGTGAT +GTTAGCCATACCCCAAGCAATGCTAGAAAAAGTCAGACCTTATCTGCACTTCTGTCTGTG +TCCTAGGCTGCACACCTAGTACATAATTAAAATGCTTACCAACCAGGGTTTTCACCAAAA +GTAAAAATCGCTGAAAGTTAACATTGTAACATGTAATTGAGACTACTGAAGAATAGTTCT +ACACATAAGGTGTGTAAGGAAAGTGAAATGTGTTTTTGGTAAAAGATCATTAGAAGTCAT +GAGAATGTAAATTTTCTTCCTTAGATTAAATGGTTAAATTATTGTTTTAAGTTAGATAGA +ATGAAGCTGAAGGTTTAAGAAAGTTTTGGAAAGTGTGAAAAATTAATTGTAGGACATTCT +GTGTGTGAATATATTAGTTAAAGTTAAAGGGGTATTCAGTTTTTCTATAAATTAAACATT +GGAATAAAAGCACAAGTTTTTTTAGAGCAAAAACCTGCTATGATTTGCTCTTTAACAAAA +ATATGTAAAGGGTTATAAAAGGTTTGTGAGAATCTTACCTTATAGTCAAACTGATTAAGA +TTGAATACATTTGTCTATAAGGTTTTATAAAGAATTGGGTTTGTCATCAATAATGCACTA +ATGCAAGAGTCACATTTGGCTTATTTGGTACAAAAACCACACAGGAAGCATTATCAAATG +TAAAATGGTGTTTGGATTTTTGGGGGCTGTAATTGTATAAATGTATTATTGGTATATATT +GAAAATTATTTTTAAAAGTCTTATAATTCTGATATGACTTGGTGTATATTGTGAATAATT +ATAATTGTTACATAAAATCATTGTATACCACAGAAGGAAGCAAATTTCCTTATCAATTGA +GACTTTAATAGTGGCTGTCCTAAGACTTTTTGTCATCCACACACAATTGTTGTCTTTTAA +TCCTCTTCAAAAGTTGGTTTATAATCAACTGTAGAACTCTAACAGGTGTTCTTAAATGCA +GATTTCTGATAACTTTGGAAATTGTGATATTAAAATAAAGGAAAACACTTTCAGAATACT +CATGGAGAGCTGAAATGTTCAGGAATATCAAGCAGAACAGAAGTTAACTGCATTGACTGA +ACTAATAGAAGACTAAAGTAATCATTTTAACTTTGCTTAAAATGCTGCTGATCCTTTGTT +TTGTTTTTCAGAGTCAAGGAAACTTATCTTTTGAGCTATTTGCAGCTTGTAGCAATTGAG +TAAAGTATATTGCTGTGAATAACATTTGAAGCATATTTAGTTCTCTCTACCTAATTTCTC +CAGAATGTGGAAACTATTTGTGAGTATTCTTACATTATGGCAATATAGTTATTTGCATAA +GTGCAATAAGAACCTCTTTTCTTTTGCAACAGGACACAATTGGAAACAGTGGTTATTTTA +CCAACGCTTTGACTGGAATGGCACGTTTTCCTTTAAGGAATCAAACTTGACTTGTAAAGC +CAATAAAAGCCCCTTGGGGAATTGGCCTCAGACCTTGTCTACAACAGCCCCTGTACAGGG +TTTCTGACCTGTGGTAAGTAAAGAATGTCACTTTCTACAGGTCCAGGATCCCCAGGTTAT +CTTGGGACCCCAAGAGGAGGGGAATTTACTCATCTCATAGGTATTTGAGGGTACAAACCT +ATGGCAGGGCTCAGCTCTGAAAAAGTCTTATCTGAGATTCTTTCTATGGAATAAAGTTGC +ATCAAAACCAATTTAAAAAGTGGTTATGTAAAAAATAATTATTCTCATTGCACTTTATAC +AACTAATCAGGCCAATTATAGTAAAGCAAATCAGTCTTACCGTGATTTGTCTTTAGTAAA +AATGGGAAACTGGAGAGAGAAATTATGTTTCAGAAACTGTGGTACACTTGTTATTAAATT +CTAGTCTCATCAGTTGTTTTTAAGTTTGTTTCTGCAATTTAGGCTAACCCTGCTTATTCC +TCTGAACCAACTAGTGACATCTGACTGCTGCTCAGAAGAAACAAGAGGGATGGGTAATGT +AAAAATCTAAATCAGTATTCTAATTCTGAGCACACTTATGAATCTTCCAGATATCACCTT +TTGTCAAAACTCGGAGTTATGAATTGCCCTCGCCATACTGATGCTTTCTGACTGAGCTCC +TCTCTACCCTGAATACAAGAGACTCTCATAGTTAAGCAAGAATATCATTGCTCCTATTCA +GCATGAAGAAGTTACAGAAGATGGATTTTCAACCCTCTGCAACCCTTAGGATTAAAATTA +TACAAACCTTTAGGATTATAAAAGGGAGGGGGTAATGTCAGGCGTGTGAACCAGAGCAAC +TCCATTTTGAGTAGAAGCTGTGTAAAACGAGGCTGAAACCTACTAGGCTGCATTCCCAGA +CAGTTAAGGCATTCTAAGTCACAGGATGAGATAGGAGGCTGGCATAAAATACAGGTCATA +AACAGCTTGCAGATAAAACAGGTTGCAGTAAAGAAGCTGGCTAAAACCCACCAAAACCTA +GATGGTGACAAGAGTCACTTCTTATCATCCTCACTGCTACACTCCCACCAGTGCCATGAT +AGTTTACAGATGCCATGGCAACATCAGGACATTACCCTATATGGTCTAAAAAGGGATGCA +TGAATAATTCACCCCTTGTTTAGCATATCATCAAGTACTAACCATAAAAATGGGCAACCA +GCACTCTGTCTATGGAGTAGCCATTCTTTTATTGCTTTACTTTCTTAAACGTGCTTTCAC +TTTACTCTGTGGACTCATCCTGAATTCTTTCTTGTGTGAGATCCAAGAACCTTCTCTTGG +GTTCTGGACCTGGACCCCTTTCCTGTAACATCTTTCTGGTGACCCAGATGAGCCTATAGT +GCAGATATTCCCAGTAAGTGCTAGGATCCTGTAACGTCTTTCTGGTGACCATGGAATGGT +CCCACTATACTGTGGAAACCCCCAACTCAAAGGCTAACTTTGGGTAAGTGGTGGGGTCCA +ATAAGAAAGTTAGTGTTAATTTTGTGCAAGGTTTCAGTTCATATTCTGATTTCAGTTATC +AAAATGTAATTGACAATAGATGCATGGGTGTATTTCTGAACTCTCTGTTCTGTTCCTTCC +ATTCCTTCCATCTATGTACTATAAACCAAAAGTATCTGAGGCAAGCCTTAATCAATTTAG +AAGTTTATTTTGCCAAGGTTAAGGACATCCCCGTGACACAGCCTCAAGAAGTCCTGACAA +CATGTCACCAAGGTGGTCAGGCTACAGCTTGCTTTTATACATTTTAGGGAGACATAGGAC +ATCATTCAATACTGTAAGATGTACATAGCTTCAGTCCAGAGAGGTGTGACAACTCAAATC +AGGGCTTCCAGATCACAGGTGGATTCAAAGATTTTCTGAATGGCAATTGGTTGAAAGACT +TATCTAAAGACCTAGAATCAACAGAAGGGAGTGTCTGGGTTAAGATATGGGGTTGTGGAT +ACCAAGGTTCTTATTATGCAGATAAAGCCTCCAGATAGTAGGCTTCAGAGAATATCAGAC +CTAAAAAGTCTATTCTGTCAGTCTGAAAGTCGCTGTTTCTATGTTAATGCTGGTCAGCTG +TGCCTGAATTCCAACGGGAGGAATGTTTAATGAGGCATGTCTGACCACCCATTCCCATTG +TAGCCTGAGCTAGTGTTTTAGGTTTACTTTAAAATGCCCTAGCCTGGTGCAGTTGTTCAT +GCCTGCATTCCCAGCACTTTGGAAGGCTGAGGCAAAAGTATTGCTTGAGTCCAAGAATTT +TAGACCGACATGGGCAACGTGGCAAAATCTCGTCTCTACAAAACAATACAAAAATTAGCC +AGGTGTGATGGCCTGTGCCTGTAGTCCTAGCTACTCGGGAGGCCGAGGCTGGAGAATTGC +TTGAGTTCAGGAAGCAGAGGTTGCAGTGAGCTGAGACTGCACCAGTGCACTCCAGCCTGG +GCAACAGAGTGAGACTCTGTCTCAAAAATATAAAATAAAATAAAATAAAATAAAGTAAAG +TAAAATAAAATAAAATATAAAATAAAATAATAAAATATAAAAAATATACCCTTGGCCAAA +AGGAGGGGTCCATTTCATTGGTTGGGGAATTTAGAATTTTATTTTTGGTTTACAGTATCT +CTTTTTTTTTCTTTTGTTACAAATGGGGTTCTTACTCTGTTACCCAGGCTGGATTATAGG +CATGAGTCACCGTGCCAAGCTATATACATATTTTTATGCCAGTACCACAGTCTTGATTAC +TCTAGCTTTATGGTAAATTTTGAAATTTTGAAATCATGTAAGTCCTTGAACTTTGTTCTT +TCATTAAATCATATTGGCTTTTCTTGGTCCTTTGGATTTAAAAGATAAATTTTAGGTTCA +TCATATCAATTTCTTTTAAAGCAAACCCTAATGGTATTTAGATAGAAATTATATTGAATC +TATGGATCAATTTTGGGAAAACTGACACCTTGATGATACTGTATTTTCCTATTTGCAAAC +ATGGGACATATCTCCATTTATTTAGGTCTTAATTTCCTTTGACAATGTTTTATAATTTTC +AGTGTACTGTCCTGTACTTCTTTCATTAACTTTATTTCTAAATCCTTTATTCTTTTTATG +CTATTTGTGAATGTAATTTTTTAAAATTTCCTTTGCAGTTGGTTGTATGTTGATTTTTGT +ATTTTTATTTTCTTACCTTATTGCACTGGCTGGAACTTTTAGTCCAAGGTTAAATAGAAG +TGGTGAGAGTGTACATCCTTTTGCCTTGCACCCAGTCTTAGGAAGAAAGCATCCAGTCAT +TCACCTTTAAGCATGTTGTTAGTCATAGGTTTATGTAGCTGCCTTTTATCAAAGTAAGAA +AGTTTCCTTCTATTCCTAGTTTATTGAGAATTCTACCATGAATAGTAGTTCAATTTTATC +AAATGCTTTGTCTGTGTCTATTGAGATGATTATATGGCTTTTTCCTTTAAGGGTCAGCAA +CATTTTCCAGAAAAGGCTATATAGTAAATATTTTTGGTTTTGTGAGCCATATGAGCTCTG +TTGCAACCAATCAACTCTGCTTTGTAGCAGAAAGCAATCATAGACAATATGCAAATGAAT +GGGCTTGGCTTTGTTTCAGTAAACTTTATTTGCAAAAACAAATGTCATGCCAGATTTGGC +CCAAGGGCTATAGTTTGCTTTTGGCTATAGTTTGCTGACCACTGATTTATTCTATTAATA +TATGTATTACATGAATTGATACTCAGATGTTAAGCTAAAGAACATTCCTGTAATAAATCG +ACCACACTTGGTAATAGTGTATAATCCTTTTTGTACATTACTGGATCTAATTTGTTGTTA +TTTAAACAATTTTAGCATTTACATTCATGACGAGTGTTGTTCTATAATTTTCTTGTGATA +TCTTTGTCTGTGGCTTTTAGTATCAGGGTAAAATGAGCTGTAAAGTGTCCCCTTCTATTC +TTGAAAAGATTTCCATTGGATTGGTATTATTAATTATTTAAATGTTAATAGAGTTCCCAA +TAAAACCATGGAGGCCTGGACTTTGCTTTGAAGAAGATTCTAAAATAATTTAATTAAACG +CTTTAATGTTTTTCACTGATATATATCTATGCAAATTGTATAATTTCTTTTTGAGTCTAC +TTTGATCATTTCTGTTAATGAATTTGCCCATTTCATCTAAGTTGACAAATTGTTGGCATA +AGGTTGTTCAAAATATTCCTTTATAAGCCTTTTAATTTCCATAGGGTTCAGAATGCTTCC +TCTTTTAATCCCAATTTTGGTAATTTCTGTCTTCTCTCTTTTTTTCTTGGTCATTTGACT +AAAAAGTTAACAATTTTGTAGATCTTTTCAAGGAATTAACTGTAAGTTTCACTAATTTTC +TCTATTGTTTTGCTGTTTTCTTTTTATTGATTTCTGCTGTGGTCTTTAGTCCTTCATTCT +ACTTTGGCTTTTCTTTTTGTAGTTTCTTAAGGTGAAAGCTTAATTAATTTTTCTAGGTTA +TTGAAGTCTTCCTTTCTAATTTTTAAAGCTATAAATTTCTCTCTAAATATTGCTTTACCT +GCATTAATTTTGATATGCTCTGATTTTACAGTCATTCAGTAGAAAATATTTTATAATTTC +CCTGGAGGTTTTTTCTTTGATGTGTAAACCACAAATAAAATTCAAAAGCCTCCCCCACAA +AAATCTGATTGGACTTTCTCCTCAGCCAGGGAACTCTAAAACTTACCCTGAAAGACTGGT +TCAGGCCATGAAAGGAAGTAGGGGTTGGACATGCCTCATTACACTCCTCCAGCATTAACC +AACACAAACCTTATATCTGATAAGAAACATTGATGGTCTTCTCTCTAATGCCTGCTGGAG +GCTTTGTCTGCATGATAAAACCTAGGTCTTCACAACCCTTTATCATAACCCAGACATTCC +TTTCTACTGATAATAACTTTTTCAAGCAATTGCCTTCAGAATATGTTTAGGAAGAAGTTG +AATCCCTGAATAGACCAATAACAGGCTCTGAAATTGAGGCAATAATTAATAGCCTACCAA +CCAAGTAGGACCAGATGGATTCACAGCCGAATTCTACCAGAGGTACAAGGAGGAGCTGGT +ACCATTCCTTCTGAAACTATTTCAATCAATGGAAAAAGAGGAAATCCTCCCTAACTCATT +TTATGAGGCCAGCATCATCCTGATACCAAAGCCTGGCAGAGACACAACAAAAAAAGAGAA +TTTTAGACCAATATCCCTGATGAACATCAATGCAAAAATCCTCAATAAAATACTGGCAAA +ATGAATCCAGCAGCACGTCAAAAAGCTTATCCACCACGATCAAGTGGGCTTCATCCCTGC +GATGCAAGACTGGTTCAACATATGCAAATCAATAAACGTAATCCAGCATATAAACAGAGC +CAAAGACAAAAACCACATGATTATCTCAATAGATGCAGAAAAGGCCTCTGACAAAATTCA +ACAGCCCTTCATGCTAAAAACTCTCAATAAATTTGGTATTGATGGGATGTACCTCAAAAT +AGTAAGAGCTATTTATGACAAACCCACAGCCAATATCATACTGAATGGGCAAACACTGGA +AGCATTCCCTTTGAAAACTGGCACAAGACAGGGATGCCCTCTCTCACCACTCCTATTCAA +CATAGTGTTGGAAGTTCTGGCCAGGGCAATCAGGCAGAAGAAAGAAATAAAGGGTATTCA +ATTAGGAAAAGAGGAAGTCAAATTGTCCCTGTTTGCAGATGACATGATTGTATATTTAGA +AAACCCCATTGTCTCAGCCCAAAATCTCCTTAAGTTGATAAGCAACTTCAGCAAAGTCTC +AGGATACAAAATCAATGTTGAGAAATCACGAGCATTCCTATACACCAATAACAGACAAAC +AGCCAAATCATGAGTGAACTCCCATTCACAATTGCTTCAAAGAGAATAAAATACCTAGGG +ATCCAATTTACAAGGGATGTGAAGGACCTCTTTAAGGAGAACTACAAACCACTGCTCAAC +AAAATAAAAGAGGACAAAAAAAATGAAAGAACATTCCATGCTCATGGATAGGAAGAATCA +ATATCATGAAAATGGCCATACTGCCCAAGGTAATTTATAGATTCAATGCCATCCCCATCA +AGCTACCAATGACTTTCTTCACAGAATTGGAAAAAACTAAAGTTCATATGGAACCAAAAA +AGAGCCCGCATTGCCAAGACAATCCTAAGCCAAAAGAACAAAGCTGGAGGGATCACGCTA +CCTGACTTCAAACTATACTACAAGGCTACAGTAACCAAAACAGCATGATACTGGTACCAA +ACCAGAGATATAGACCAATGGAACAGAACAGAGCCCTCAGAAATAATGCCACACATCTAC +AACCATCTGATCTTTGATAAACCTGACAAAAACTAGAAATGGGGAAAGGATTCCCTATTT +AATAAATGGTGCTGGGAAAACTGGCTAGCCATAGATAGAAAGCTGAAACTGGATCCCTTC +CTTACACCTTATACAAAAATTAATTCAAGATGGATTAAAGACTTAAATGTTACACCTAAA +ACCATAAAAACCCTAGAAGAAAACCTAGGCAGTACCATTCAGGACATAGGCGTGGGCAAG +GACTTCATGTCTAAACACCAAAACACCAAAAGCAATGGCAACAAAAGCCAAAATTGACAA +ATGGGATCTAATTAAACTAAAGAGCTTCTGCACATCAAAAGAAACTACCATCAGAGTGAA +CAGGCAACCTACGGAATGGGAGAAAATGTTTGCAATCTACCCATCTGACAAAGGCCTAAT +ATCCAGAATCTACAGAGAACTTAAACAAATTTACAAGAAAAAATCAACCCCATCAAAAAG +TGGGTGAAGGATATGAACAGACCCTTCTCAAAAGAAGACAGTTATGCAGCCAACAGACAC +ATGAAAAAATGCTCATCATCACTAGCCATCAGAGAAATGCAAATCAAAACTGCAATGAGA +TACCGTCTCACACCAGTTAGAATGGCGATCATTAAAAAGTCAGGAAACAACAGGTGCTGG +AGAGGAGGTGGAAAAATAGGAACACTTTTACACTGTTGGTGGGACTGTAAACTAGTTCAA +CCATTGTGGAAGACAGTGTGACAATTCCTCAAGGATCTAGAACTAGAAATACCATTTGAC +CCAACCATCCCATTACTGGGTATATACCCAAAGGATTATAAATCATGCTGCTATAAAGAC +ACATGCACACGTATGTTTATTGTGGCACTATTCACAATAGCAAAGACTTGGAACCAACCC +AAATGTCCATCAATGATAGACTGGATTAAGAAAATGTGGCACATATATACCATGGAATAC +TATGCAGCCATAAAAAATGATGAGTTCATGTCCTTTGTAGGGACATGGATGAAGCTGGAA +ACCATCATTCGCAGCAAACTATGGCAAGGACAAAAAACCAAACATCGCATGTTTTCACTC +ATAGGTGGGAATTGAATAATGAGAACACATGGACACAGGAAGGGGAACATCACACACCGG +GGCCTGTTGTGGGATTGGCAGAGCGGGGAGGGATAGCTTTAGGAGATATACCTAATGTTA +AATGACGAGTTAATGGGTGCAGCACACCAACATGGCACATGTATACATATGTAACAAACC +TGCACATTGTGCACATGTACCCTAAAACTTAAAGTATAATAAAAAATAAAATAAAATAAA +ATAAATATATATTTTAAATATACATTTATTTTAAATATATAAATATTTAAATAAATATAA +ATAATTATAATTTATAATTTATTTATAATAAATAAATAAAAATAAAACTATATGGAGCCC +TTAAGTGTTTTAGGTACTTGACATCTATTGTGTATTATTACCCCCATTTAATAGTTCAGG +AAACTCAGACCCAAAGAGATGGAGGAACTTCACTAAGATTACACAGTGAGTCACTGCAAA +GTTGCAAAACCTGGTCTGACTGACCATCTTGCAGGATATTCCCTTTTTTTTTTTTTTTTT +TTTCTTAGATGGAGTCTCACTCTGTCACACAGGCTGGAGTGCAGTGATTTGATCTCGGCT +CAAATTTCAAAGCAATGAAATTCCTGAAAGCCACTTAGTTATTGGGAGAGAAGAAGATTA +AAAGAAAGAAAAATTAGTGAGTGAAGAATGGAGAGGTATTGGATGGGAAGATATTGTGGG +AGAAATGGAATCTTGAAACTAAGGAGATTGGCCAAAGGTTTTTGTTTTTTGTTTTTGTTT +GTTTGTTTGTTTTTGAGACAGGGTCTCACTCTATCACTCAAGCTGGAGCACAGTGGAAAA +ATCATGGCTCGCTGTATTCTTGACTTCCTGGGCACAAGCGATCCTCCCACCTCCACCTCA +GCCTCCAGAGTAGCTGGGACCACAGGAACATGCCACCATGCCTGGCTAATTTTTGTATTT +TTGTAGAGATAGGGTCTGGCTATGTTGCCCAAGCTGGTCTCAAACTCCTGGGCTCAAGAG +ATCCTCCCCTCTCAGCCTCCCAAAGTGCTGGGATTGGTGTGAGCCACTATGCCCAGATGA +AAGATTCTTTAGTCCAGTAGACACACACACACACACACACACACACACACACACACACAC +ACACACACACCTCAGTTCAAATGAAATCTCAGCTGGGATCCCATTCAGGTCATCAAAATC +GTTAGCATATTAACATTTATTGAGCACTCATGTGCCAGGTATAAGGCCCAGCTCTTTTCA +AACATGATCTCATTGAATCCTCCCAACAGCAGAATAGGTAATTTTATTAGCCCCATTTTA +TGGATGAGGTTTTTTGTTTTGTTTTGAGATGAAGTCTGGCTCTGGCGCCCAGGCTGGAGT +GCAGTGGCACAATCTCAGCTAACTGCAACCTCCACCTCCTGGGTTCAAGCGATTCTCCCG +CCTCAGCCTCCTAAATAGTTGGGATTACAGGCATGCACCACTACACCTGGCTAATTTTTG +TGTTTTCAGTAGGGACGGGGTTTCATCATGTTGGCCAGGCTGGTCTCCAACTTCTGACCT +CAGGTAATCCACCTGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCATG +CCTGGCCAAGGTCAACTCTTTAACATCAAAGCTGGACTCCAACCCAGGTGTCTCTTCCAC +TAGGTATCTGAAGAACTTGTCACCCACTCTGGGATGGATAGGCCATTAGGGAGAGTCAGG +CTGGGTTAGGGAGATGTGGATGAGGGAGAGGCTCACCCAAGAAGTGGAGGGATGGGACGT +AGGAGTCCTGACTGCTGCCCCAGACTCCTATGAAATAAAGAGATGAGCTCAGCTTGTCAC +TGGAAAATCTCTGTGGAGTATTCATTGTGCCTGAAGTTCTATGATGGTGGCAGTGGACAG +ATGAAAAGTACTATCTCTTAAAGAGATTAAGTATGTTTGAACACAACTTCATTTCTTGTT +GAAAATACATTTCATTTCCCCTCCCTTCATTCCCCCACCAAATGCATTGTACTGCTTTGG +AGTACTTGGAAAAACCAGTTTAAAAACCTTGAGGCTGGGTATGGTGGTTCATGCCTGTAA +TCCCAGCACTTTGGGAGGCCAAGGCGGACGGAATCACCTGCGGTCAGGAATTTGAGAACA +GCCTGGCCAACATGGTGAAACCCTGTCTCTTCTAAAAATACAAAAATTAGCCGGATGTGG +TGGCAGGCCCCTGTAATCCCAGCTACTTTACTCTGGAGGCTGAGGCAGGAGAACCACTTG +AACCCAGGTCGCAGAGGCTGCAGTGACCTGATATCATGCCACTGCCCTCCAGCCTGGGCG +ACAGAGCGAGACTCCATCTCAGAATACATACATACATACATACATACACACACACACACA +CACACACACACATACAAACCTTGCTGGATGCACAGTAGACTTTGTTCCTTCCCTCTACAA +CATTTCTCCATGACCTGGAACAAAAAGAAGGGAACTTCTGTTTACTGAGCACCTATGACC +TGCAAGGCATTTTATATCTTACCTCATTCATTCCCCACAACAACACTTGTCAGGCATCAC +GCCTATCTTACAGGCAAGAAAACCAAGGCACAGAGAGGTGGAGGAACTTAATGTCAGATG +TGAACCAGGCCATACGATGCACAGGGCGTGCTCTTCCCATGCCAGGCTGCCGCCCCAGTG +ATTCTCAGCTTCATTATGAGCACAGAGTTTATTTCAGCCATTATTGGCCAAAGGAACTGC +TCTGTGAGGGATGCCCATGTTTGGAGCCTTCGTTTATGGTCCCTGGCCACTGACTCTTCT +CCTACGGCTGTAGCTGTTGAGGACAGTGGTTGATAACATGTCAAGAAGGAAGCCTGGGAT +GAAGACTTATTCCCCACACTGCAGGTCCTAGCTCCAGGCTGTCAGGCAGGGGCAGTGATT +TCAGAATGTGAAGGATTCAGAATTTGGTGGGTCCAGAGGATCCTGCCAAAGGGTTAGCCA +GCTGGAATCAGAGGGGTAACTTGTCAGGGAGCAGGGGGAGGTAGGTAGCTGCTGAAGTTG +CTGCTAAGAGTGATCCCAAAGTTCTGACATATCTGTCTCATCCATCCATCCATTCATCCA +TTCACTCACCAATCCATCCATCCATCCACTCATCCATCCATCCACTCATCCATCCAACCA +CTCATCCATCCGTCCATCCATCCATCCATCCATCCACTCACCTATCTATGTGGCCCTTGA +ACACACAATCAGAACATAAAGGTGGAAGAATGGGTTTTCTTCTTTGCTGTGACACCTCTG +GCTTTTCCTGATCAGTGATGGGGACCTGCAGACTGGGAGTGCTTCAGCTCTGGTTCACTC +TGATCTTGGGCAAGTTACCTCTCCACTCTGAGAGGTTGGGGAGGTGGAAGAAACCATATA +GCTGTCTTGTGCAGATCGCCCCTCCTATTTCATCGATGGGTGACTGAGCCTGGGAGTAGG +AAGGTGACTTGCCAAGGTCAGGTAAGGAATTAGTGGTAGATTTGGTACTGGATCCCAGGA +TCCTGCTGCTCATTTGTAAAGTGAGAATGGGAATCCCGGCTTTCCTCACTTCCCAGGATT +GTAGAGAGGACCCCATGAGATAAATGGTGGGAAAGCATTTTGACAGGTGAGGTCACAAGG +CCAAAAGGTGCCAAATGTGCACCTGGGGCCCTGGCTGCTAGACTAGGGCAGATCCCACAG +AGACCAAAAGGGGTCAGCAGAGGCTTGTGCTTAAATGCTCAGCTAGGATCTGCTGCAAGG +CACAATGCCTGGGTGCTGGGATTGGGGAGGGAAGCAAAGTCATTTAATTTTTTGAGACAG +AGTCTTACTCTGTAGTCCAGGCTAGAGTGCAGTGGCACTATCTCGGCTCACTGCAACCTC +TGCCTCCTGGATTCAAGTGATTCTCCTGCCTCTGCCTCCTGAGTAGCTGGGATTGTAGGC +AGGCACCACCACACTCGGCTAATTTTTGTAGAGATGGGGTTTCACCATTTTGGCCAGGCT +GGTCTTAAACTCCTGACCTCTAGTGATCTGCTCTCCCCGATCTCCCAAAGAGTTGGGATT +ATAGGTGTGAGCCACCGCGCCCATCAATTTTATTTATTTATTTATTTATTTATTTATTTA +TTTATTTATTTATCTGAGACAAAGTATTTCTCTGTCGCCCAGGCTGGAAGTGCAGTGGCA +CAATCTTGGCTCACTGCAACCTCCGCCTCCCGGGTTCGACTGATTCTCGTGCCTCAGCCT +CCCTAGTGGCTGGCATTACCGGTGGGCGCTACCACGCCTGACTAATTTTTTTATTTTTAG +TATAAACGGGGTTTCATTATGCTGACCAGGTTGGTCTCGAAAACTCCTGACCTCAAGTGA +TCCGCCCGCCTTAGCCTCACAAAGTGCAGGGATTACAGGCATGAGCCACGGCACCCAGCC +TGGCCATTTTTCTGTAGAATTCCAGGAACAGGCTGAGTGGGGATGGGGGTGGTTCTGAGG +CTACTAAAGAGAAGAGCCAAAGATTGTATAGGTAAATTCTACCTGCCAACGCCCTAGACT +CAAATGCATCAGGCTCACCCCAGGAAGGGCAGCTAGGGCTGCCTTGTTCTAGAGACTATA +TGAAGGGCAAGGAAAAAGCCTCCTGAACCCAGGTGGAAGCCTAAATGCTAAGGGATGTTC +TGGATCCTCATCATCAGATAATCCAGAGAGAAGTGAACTGATGGCCCCTCAAACCAGTGA +GTAATGGGAATAAAGGAATGTGCTGTTCATCACAGCAACTAAAAGTCTGCAGGAGAGACA +ATGCTCTTGAGGGTAAGGGTAGTGATAGGAGGAGGGTCAGTCATTTTCATGCTAGTTAAG +AAATATTTATCAGGCACTGTATTAGGTGTTGGAGATACTGAAATGTACAAGACAGTCATG +GCCCCTTTTTTCAGAGCTCAAAGTCTAGTGGGGGAAACAGACATTAAATAGGCAATTACA +GGCAGACAGAGCTTAAAAAGAGGATAACAGTGGCTACCTTAAAAGGATGTTGTGAAATTT +AATGAGATAATCCAGGTAAAGAGTTTTATCAGGGCTTGGCACAGAGTAAGCCCTCTAAAA +ATGATAACTATTTTTCTTGCTTTGGATAGGGAAGTTAAAATGAAGGGCTCTGTGGAAGTG +AAGTGTGAAGAGAGATCTATTCCAGGTCGGAGGCTAGGGAGTCCCAAGACCGCCTGAAGA +AATCACAAGAAATCTGAAGAACTTTTAGCTTGAGGGAGAGGGAGGGGAGAAAAAAATAGC +AACTCGTTAGCAGTTCAGTTTCACCACTTTACAGCCTATGAAGTCTTTGGCTTCCCTCAT +CTGGTTCGATCTTCAAACCTAACCAGACCGGCATCTAGAGTTAATATTTCCATTTTACAC +AAGAGGGAAGTGAGACCCAGTGGGAAAAATGACTTGTTCAGAGTCATAAAGCAAAGTCCG +GAAGCAAGTCTTTCTGGTCCATTATGTGTGGGAAAAGTAAACAAAAACCGCGGGGCGTTA +CCGAAATATTAGGTTATAAACGTGGAACAAAGTCTAAGAGTTAACGAGAGCGAGGCACCA +CTTATAGGGGTGGGCCAGGTAGGTTTCCCGGGGGAGCTGGCATTGGAATAGGCTTCTTCG +CCTGCTCGGTGTCAAGACCCCGCAGGAGATGGCGGATTCATTCAGGAAGCAGCCGCTCCG +GGAAGCCTTAGCCAAGGGTCTTCCGGAAAGACACCAGTCTTGATCCTGGAGCCTCAATCC +CCGCTGACCCAGCACTTTGGTTTCCATAGCAATTGTCTCGTCGCAGAAAGGAATCGCCTG +TGCTGGGTCTTCAGACCTCAGCTCCATGCCGCTGAGCAGCCCCACCCTGGCTCAACCCGT +TACCCGCCCCGCCAGCAGGCCGGGGTCACTGCAGTCCCCACGTCGAAGCGGAAAAGGTCT +GCTCAGCTCACCGCACCCCACTTCTTCCAGACCCGTCCGTCTTCACAGCAACGCGCCGGG +TCTCACCACGGCGGATGCCGAGGGACAATATTACCGCGTCCGTGGCCGCCGGACTCTGCA +CGCATGTCCAACAGCCCCCGTCCCCTTCCCCGCAGCCAATATGTGTCTCCCAGGCAACGC +GC diff --git a/test/csq/ENST00000519442/ENST00000519442.fa.fai b/test/csq/ENST00000519442/ENST00000519442.fa.fai new file mode 100644 index 0000000..373a3dd --- /dev/null +++ b/test/csq/ENST00000519442/ENST00000519442.fa.fai @@ -0,0 +1 @@ +5 45842 25 60 61 diff --git a/test/csq/ENST00000519442/ENST00000519442.gff b/test/csq/ENST00000519442/ENST00000519442.gff new file mode 100644 index 0000000..26ed0b0 --- /dev/null +++ b/test/csq/ENST00000519442/ENST00000519442.gff @@ -0,0 +1,16 @@ +5 ensembl_havana gene 21 45822 . - . ID=gene:ENSG00000039600;Name=SOX30;biotype=protein_coding;description=SRY (sex determining region Y)-box 30 [Source:HGNC Symbol%3BAcc:30635];gene_id=ENSG00000039600;logic_name=ensembl_havana_gene;version=6 +5 ensembl_havana transcript 517 45822 . - . ID=transcript:ENST00000519442;Parent=gene:ENSG00000039600;Name=SOX30-004;biotype=protein_coding;havana_transcript=OTTHUMT00000373922;havana_version=1;tag=basic;transcript_id=ENST00000519442;version=1 +5 ensembl_havana three_prime_UTR 517 681 . - . Parent=transcript:ENST00000519442 +5 ensembl_havana exon 517 1063 . - . Parent=transcript:ENST00000519442;Name=ENSE00001596998;constitutive=0;ensembl_end_phase=-1;ensembl_phase=2;exon_id=ENSE00001596998;rank=6;version=3 +5 ensembl_havana CDS 682 1063 . - 1 ID=CDS:ENSP00000427984;Parent=transcript:ENST00000519442;protein_id=ENSP00000427984 +5 ensembl_havana exon 12572 13064 . - . Parent=transcript:ENST00000519442;Name=ENSE00000972591;constitutive=0;ensembl_end_phase=2;ensembl_phase=1;exon_id=ENSE00000972591;rank=5;version=1 +5 ensembl_havana CDS 12572 13064 . - 2 ID=CDS:ENSP00000427984;Parent=transcript:ENST00000519442;protein_id=ENSP00000427984 +5 ensembl_havana exon 20979 21158 . - . Parent=transcript:ENST00000519442;Name=ENSE00001234728;constitutive=1;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00001234728;rank=4;version=1 +5 ensembl_havana CDS 20979 21158 . - 2 ID=CDS:ENSP00000427984;Parent=transcript:ENST00000519442;protein_id=ENSP00000427984 +5 ensembl_havana exon 22999 23238 . - . Parent=transcript:ENST00000519442;Name=ENSE00000797253;constitutive=1;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00000797253;rank=3;version=1 +5 ensembl_havana CDS 22999 23238 . - 2 ID=CDS:ENSP00000427984;Parent=transcript:ENST00000519442;protein_id=ENSP00000427984 +5 ensembl_havana CDS 42140 42191 . - 0 ID=CDS:ENSP00000427984;Parent=transcript:ENST00000519442;protein_id=ENSP00000427984 +5 ensembl_havana exon 42140 42194 . - . Parent=transcript:ENST00000519442;Name=ENSE00002105000;constitutive=0;ensembl_end_phase=1;ensembl_phase=-1;exon_id=ENSE00002105000;rank=2;version=1 +5 ensembl_havana five_prime_UTR 42192 42194 . - . Parent=transcript:ENST00000519442 +5 ensembl_havana exon 45672 45822 . - . Parent=transcript:ENST00000519442;Name=ENSE00002116582;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00002116582;rank=1;version=1 +5 ensembl_havana five_prime_UTR 45672 45822 . - . Parent=transcript:ENST00000519442 diff --git a/test/csq/ENST00000519442/synon-splice-region-del.txt b/test/csq/ENST00000519442/synon-splice-region-del.txt new file mode 100644 index 0000000..b584f48 --- /dev/null +++ b/test/csq/ENST00000519442/synon-splice-region-del.txt @@ -0,0 +1,3 @@ +42130 ACA A intron|SOX30||protein_coding +42130 ACA A intron|SOX30||protein_coding + diff --git a/test/csq/ENST00000519442/synon-splice-region-del.vcf b/test/csq/ENST00000519442/synon-splice-region-del.vcf new file mode 100644 index 0000000..79df8a3 --- /dev/null +++ b/test/csq/ENST00000519442/synon-splice-region-del.vcf @@ -0,0 +1,7 @@ +##fileformat=VCFv4.2 +##contig= +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO +5 42130 . ACA A . . EXP=intron|SOX30||protein_coding;type=ENST00000519442:157094796-ACA-A, ACA--TACAAACC is the same as A--CATACAAACC, just outside the splice region diff --git a/test/csq/ENST00000520795/ENST00000520795.fa b/test/csq/ENST00000520795/ENST00000520795.fa new file mode 100644 index 0000000..7c7042f --- /dev/null +++ b/test/csq/ENST00000520795/ENST00000520795.fa @@ -0,0 +1,4550 @@ +>8 8:80870571-81143467 +TTATCTTTTACGATGTTTTCCAAAGTCAGAGTTGGAAGAAAAACAGGTTATCATCACTTG +TGAAAATCTCCTCCAAACAGCATACCACGAAATGGGACTCCTGAGTGAAGGAGAAAATGT +TGAGATTCAGAAGAACTCAAGGCTATTTTAAAAATAATTTTTATTGCTAATTTTATTTGG +TACACTAACAATTTTTTAAAAGGCATTTATTAAGAAAGAGAGTCACTAATTGATTTTGTT +GAGTTTTTCTTTAATGTAAAAAGGGCTGTCCTGAGCCTTTGCTGATAGGCATATATCAAC +ACAAAGTGATTTAGCGATTTAGTGAATGACCACTGCCCTGATATTCTGTTCTGTTAACAC +AGCTAAAATACTAACAAATGTGATGTGTGCTCAACACAACAAACACTGGATTCTGCTGGT +ATGAAGTGTCAGGGTGAGTTTTTCTTATGTCTTGTGAGAAATGTTTCACATTTAACCCCC +AAGTATATAAAAATTAGTTTGGATTTACTCAATTCACTTAAATTAAGCAAATTATATAAC +TGAGTTTAGTAAGAATTTACTGTGAGTCTTGTACCAACACTGCCTTAAAGATAGACATGG +GGTTACAATCTAGTTTTGGAGACTATATGAGTTAAAGAAACAATGCAAGATTATCTATAA +ATTAGTGGTATAGACAACCACAACATACACTATATATATTCAACTAGAGCTACATAACAG +ATTTTAAAGTGAAATCCTTCCCTCTTTCACAGTGTGAACTTGTAAAGCACTAGACTGTAC +AGGAATTACGTTATTTTAACTGCAGTAAAGATTACTGAACTAATGACATTCTATTGCTAA +CCGACTTTAATAATAGCAGTAAATCAGCTCCAAAATACTGTTATTAATATTCTTATGACA +CAGAAATAGTGCTGTATTAAGTAATGTTCAAAGAACAGGTCTCACAAGCTGAGAGCTAGA +GATCTTTATTATAAAAAAGCTATAAAATATGAAAAAAAAATTCAAATTGTTATTCCCAGG +GAGGTATTCTACCTATTTTTAATAGTTATAGGAAAATTGGCTTTTCTAACTGAAAAGACT +GTAATGAAGCTTTTTCTAAGAACTACAAGATTCTATGTTATATATCTGTTGTATACACAT +AGTTTTTAAAAGTTAGATTTCATTCTGAAAGATTGAACGGTACAACTTTAAATGAAAGGG +AGACAAGGAGATTGCTAATACAAAATGGTTTCCCTTATCTGAAATATAATTTTACATAGA +AAAACTTTGCAGCAAATAGAAATGTAAGCACATTTACAATATGGGTTTTGGGTATGAAAG +AAAGGTTACCACAGAAATTTTAGTCCTAAAAAACTGAGTTATCAACCATCCAAATAGCAA +ATCTATTTATTTTAGCTAATAAGACAAGTAGAAAATATTAGATTATAATCCTAGGCTTTT +AAGAGCTGTATACTTCATAAAACCAGTATATATGTTTAAAAAACACTTATAACTATGCTT +TATTTCAGAGGCTCATAATCTTATAAGCCAATATTAATTTTATCAAGAAAGCAACAATAA +ACTATGTACTTTCTCTTCTTGAAAAAGCACAGAGGCTAAACATTGATTTAAACGTCTCAA +CACTGCCAAATCTCCCACGGATTATTCCCAAACCTCAAATCCTGACAACATCCTGTTTTA +CAGGGGTGACTGCTTTCCACATGGTGCAGTCTCAGAGAGACCACAGGGCTTTCCTTGGGG +TTTAGGCTGGCCTTTCCTTGAACAGAGCAAAGCACTGTGGAGTGAATCACTACAGAAATC +CTGCCATGACAGGTACTCTTGCTTCCTTTTTAAAGAGACAAATAGGAAAGCTAGATGGGA +AAATGCCTGGCTGCTTTGTCCCTTGTCTGCACAGCCCCTCACTTTCCCACAACAGGTAGG +CACAAGCATAGAATGCTGCTGCAGGCTGTAGACCTTGCCAAGAAGCTAAAACCCACTGGT +TTCTACAGTTGTCCCAGGCAGACCCATTTTCTACTAATCCTGGCTCTGTGCCAGAGCCTA +ATTAAGTCACTGAGAATGCTGGATGGTTAACCCTCTCTGCACCCATCTACAATTATTTGC +AAAGCACTTCGATATGCTTTCACTTTTCCCAAAGATATGTGTACCAGACTGTCTCAATGT +ATAGCAGTGTGAATGTGGGTGGGTGCATGCAGGTACCCCACAGGCTAGTACTTAATACCA +GTGTATGTACTTACTGTAAAGAAAGAGAAGCTCAACTGTGAAGGCTAGCATTCAGGAAAC +CTTCCAAAATATATGTGTGGCTTAGTTTTATTAGTTAGGATTTAAAGAAAAGTGCAGAAG +AATTCTACATTTTAATTATGCTTAATCTTAGGGAAATAATTTTCCATTAAAAGAAAAAGA +AAACAAGTATTTAGATCACAATGTCTGTTGTGAATCCTTTTTACCACAGGAACAAAACAT +TATAGAGCTTTTGAAATTCCCAGAGCCGCTGCTGTTCATTAAAAAAAGAAAGCACCCTTT +TAAGATTTAGGTGCTTTATCTTTTACAAAATGAAAAGATCAAACATAAAACCTTATTTGT +AAGCAAGGCAATAGTGTCTCTGGGTTTCTTGCTAAGATCAACAGCAATGAGGATGAATGA +GGGGAAGCAGTGACAATGGTCAAAATGGGTGAAAGGAAGCTCTCTGTTGAGGCCGGCCTT +CCCTGATTTCAATCTTTAGACCCAAGGCCCATAACTCTGTTTAACTACTATATCCTGAAT +AAAAAGTTAATTCTACTCTAATGAGAGGCAAGTGAAGCTGAACGATGAGAGGAACACTGA +GTAACCTAATTGAGCCCATATAATCTGATATCAGAGATCTCTACTTGAAGATAATTCAAG +AATATCTAAATTGGAATTCAGGAGAAATGCAGGAAATTGATTAGTCAGGCTAATTATTTT +CCCTTTTTGACAATAGGATATCCCAGTATACACAATACATAATTAAGTAATCTTTTCTCT +TTCTCTATTCTTTAACAAGAGACCTGCTACAGATGTTCAGCTTCCAACTTCCTGTTAATA +TTGATGCAATTTTCTATGGACCAAAATGATAGGAATCATTTTTCAGCTACCCAAATGCCA +AATTCATTTTATCCCAATAACTTTTCTCCATTCTTCTCATGCTTCAATTACTTGCACTTA +CAACTCCTATTACTTTATAGGAAAATAACACCAAAATTGAAAGGTTTTCTTAAAATTATC +ATGGATACACAGGAATATTTCTATTTAGTGAAGACAGAGTATTTCACACCTATGCACCAC +CACAATATGGCCAAAACAAAAGAGTGGCTTAATTAATTGCTGGCCAAGAGCCACGTTCTT +TCCCAATCAGGGCTTCTGCAAGATGGCATATGGTTTGCTATTTCTTACAAATATGAAAAG +CCTTTTGAAGTGATTACACTTAGTATCTGTCAAAATAATTCTGTATGTGAAACACCAGCA +CTGAAAAATGAAAGAAGGTATTATTTATGCAAGACGATTTCACTTTAAGTTTGAAAATAA +TTTTCATTTCTAAGGATTAAAATACTGACCAGCATGCCATTTGAGTAAATATTATTTTTA +TTCCACATACTGTTCCATGTAGAAGATGTCAAGTTTACTTAGGAACATTAATGTTAAATA +TTATTTTTTAAGTGGAACGAATATTTCTTCATTATTGGCCCACATTTTCTAAGGTAGAAC +ATATTTAATACTTAATTTTTTATCTTATTTTCTGTATTAAATTCAATCACTGTGCCATCT +TTTCAAAACTGCGCTTGTAGTGAGGATGGTTAAAAAAAAAAGGAGAAGGGTAACCTGAGT +TCCCAGAGGGTAGTAGTTTTATATTATTCGTCGTTGTATTTCCAGTACCGAGGATACAAG +AGGTGATCCTGAATGGCCATGCTTTGAATAACCACCAGAAGCTACAGGAGCCCAGTGCAA +CCACCCAAGCTTACTCTGAGAAGCACAAGGCAAGGGGGTATGAGCTAAGTAAGCCCTGCT +TACAGGACTCTGGTTCAAAGGGCAGAATAATCCAGGCCAGTGGGCATCCTGAGTGCTTTC +TCATCAAGGTCCCAGTGGGATTTGTAACCATCCACTTAGAAAGATAACGCCTCCAAACAT +TCAAGAGACAGAAAGTATCAAAAAATTAGAAAAATCTTTAGGTTACAAGGTCTTAAAACT +TTTCGTCTATGTCCTACAACAGTTTCACTCCTGATATACTTCATAATACCACTAGTGACA +GCAGGAATTAGAAAAAGTAATCCAATAGATTTTTATTTTAAAATTGTACCCTAATACCTA +GCACAGAATCTACTAAGTTTTCAATAAATATTGTGAAATAATGAATTGCGGCAGTGAATG +AAAATATGAAAGTAGGGTGCTCAAATGGTAAAGGGATTTTCACGGTTAGTTGGAACGCAA +TTCTAAACATGTTTTCTTTTACTAGTATAAAAGTGATTCTTCTCCACAGGACATTTAGAA +TGTGATGTACTGGGACTAATTTATTCAAATGTTTGCTCCTTAGATCACTGAAAGAAACTA +GGAAGGATAGGCCTTATTAACATAATTGATAGCCATAAGCCTCAATTCACTCTGATGTAC +TTGCCATGCCTGGGGAACACAGACCTCTTGGAAACACTGTCCTGCATTGGAAGAGCATGG +CAATGAAACACAATGGATAAAACCCGCAGGCAAGCAAGGAAAATTACGTTATGAGGGGTA +GCCCTTTCAAAATGACTTAGTATGATGATGTGATTGTACAGGATAGAAATACAAAATTAT +CTTTACCTTACACTACTTAAAATCTAAAACTGAATCAAGATTATTCATGCTGGAGTCAAG +GAAAAGCACCGTATTCTCAAAGAAAAACATATGCAAACATCTGTGGCAGAGGCTATTTTA +AAGTATCCATCTTGTTGATCTTTTAGTCTTCTTAGCCTACTATGTATTTTCAGTTAAAAA +TCATTAAAGTCCACCATATATGAACCCAGACACAGGACAAAAACAACAACAACAAAAAAC +CACGTATTTTTTTCCATGGGGGCGGTAACCAGATGTCAATAGCTGCAGCTGTGACTATAT +AATTACCTGTTTGCATTAACATAGACCACAGTTTAGATTTAATAGGTTAGATGACAATGC +AGCAAAATGCATTTAGCCTATGATTACCCCCTTTCCAAACATTCTCTCATTCGCAACTTC +GACCCTGGGAACATAGCAGGCACAGACTTAGGTCAATAAGAAACACTGGCCAGTACAATA +GGCCTTGCCTCAAACAGCACTGTTGACAGACACCAGCACAAAGGAAATGAATAGAGTCCC +CCTCAGTTCTCACACAGAGCGAAGAATGACTCAGTGTACTGCTGCTTTGGTGCTCTGTTT +GTACAGTGTATACAGCTTTTGTCCTCAGCCACTGTTCACAGCTCAGTGGGGGCTAAAGAG +CCTAGGAAGTGAAGGCGGAAGAATGCTCCACACTCGTCCCTGTGGCCAGCAGTTGTATCC +ATATGCACATGACAGGTCAAGTGAGAACTGAAAGTCACTAGATGAAACTCTCCTACCAAG +CTTACAGGAGTGAAGTAATTTCTGAGTTAAAATATAAAAAAGGTAAAATAGAAAAGTCAC +CATTAGTTTGATATTTATAGAGTTATTGACTGAATTATTGTTCTTTTGTTTTTCTCTTTT +CTGTCATATTTCTCTTATGGCCACTTATACAACCTTTTTCAGAGGTTGGGCACAAAGAGA +AATCAGGATTGGCTTAAAGTAGGGAACTTAAGTAATGTAGGCCATTACTCAACAGAGATT +GCTGAAGTAGGGCCAGAAAGCAGGTGAGGCAATATCCAGGTCTGGAGTCTGAAGCATCAG +CAAGGGTGGGCAGTGGCTTTGCTTGTTGTGTGTATATTAATATCATATTGTCCCAAGCAC +ATACACATCTCTCTTTAGGCCCACTTCCCAAAGTAGTGGGGTATAACAATAAAGAGCCCA +AGCCAGGGATAAAATAAAATTCTAACACAATTCAGCGGAGACTATAAACAGACAGATACT +TCCACTGGCTTAAAATGGTTTGCTTGATACTGGCCAAAAAACCTAGTTAGAGCAAAGTAC +AAGCTCAATTGCTAAATGAAATGTCATTTCCCTAAGCCAGAAACATCTTGGCAGAATCAC +ATCTGTATTTAAGCATATGTGTTTTGGAATTAGACTATGTTCAAATTCTGGTTCCACCAA +TTACTAGCTGTATGATCTTACATAACCCCTCCAGTGTCTTGATTTTTCTCATCTGCAAAA +ATGAAATGCTCGCCCATTTCTTTATTTAAAAAAAAAATAACTGAGATAATAATACTAGCA +CTTACTTCATTGGAGGCTGTGAAGGTAAAATAAGTGAATACATGGGAGGTGCCTAGAAGA +CCTGGCACCATGTGAGCATTCAATAAATGTTACCTATGAGTGTTAGCCCCAACACTCACA +CTATGACCACTGCCATGATTCTACTACTATTAATAACATCAGAACCATCACCAGCCCTAC +AGCGAAGGAAGTGCCATATTCATGACTACAAGAACATTCTTGCCAGATGATCAAGATCAC +TGTTCTTGAGTCTATGAAGATATCCTATTTACCCAGAGGCTGTTTTTAGTGGTCTCTAGT +AAGTAGATGAATTCAAGCTTTATGGATGCTGTATATGTGACATAGCCATATATAATACAC +ACACATGTATTAATATTAACATTTTTAAAAGGTAAGTAATTTGAAATTTCCCTCAAGTTT +AAATCAATCTACAGCCTAATAATTATTCTTAGGGAGAAAAGACAATAACAAACATTAATT +AACTGCTCACTATTTTAGGGGCCAGATATTCTTCTAAGTGATTTCTCTAAAGTACTATTA +TTTTTACAGGAAGGAAATTGAATGATAGTGTTAAGTAACTCACTTAAGATGACACTGTTA +AATAAGCAAACCCAGGCAATTTGACTTCAGATCTTGTCATAAATATAACACTATACTGTC +TCATTAATATTCCTGTGAAAGCATCTACCACAACTTGCTAAGTAGTACTATCCTTATTCT +TATGCTTAGCAAAGGAAAGAAGTCACTGTCTTAGAAGATCTGGCATAGAATCAACCCATA +TATCCACAGTAGTCTCATAAATGATAATATATTAGGAATTATGATATGCTTAAGGTACGT +CCTTTTATCCTTTTTGAATAGGCTGGGGCTGACTATATCTGGTTTAGTAGGAGTCAAAAA +GTAAAATGCTTTAACTGCTTTCATAAATCCTCATCACTACACAGCTATAATTAGTTTCAC +GCTTATGAATTTTATCTTACATGTTAATTATATCTGCAATGATTCTGAGAATGCAAAGAA +ATTAATTAATGAAAAAATAACTGCTTTGAGAGTAGATGCTTTAAGCATATAAGTGATAAC +AGGAAGAAAAAAATGTCCATTGTTTTGATAACTTTCAGAATGTCTCTCTATGCTTAAGTC +TTCCACAGTATCGGTCAATTAAATATCAATACCAAGCAAGAACAATGTCAGCTGATTAAG +TAAAATTTTGTACTTCTTTAAAAGTTCATTTCATAAGGCTCTGATTTTATTCTTAAAAGT +CTGAGCTTCTGAACATATGTAAGTATTCATGAATGATCCTGATTTTAAAAAAGAAAGGTA +ACAGACTTCCATATCTAGCAGTATGTTAGAATGACTAAATTGACCAAAGGTTCTCCTAAA +AAGAAAGAAACATAATGGTTAAAATAACAAAAATATTTTCTTTAATTCTATTATTGAGTC +AGCAGTTTAGGAATGATTATAGAAAGGCAGAAAAAAGAAAAGAGCTACAAATCAAAAAAT +AAACAGAACACTGAAGCTGGGTTTTGCAGAACTTGAGTGAGCTTGTTTTAACATTATAGA +TATATAAAGGGTCAATATATAATAAAAAGCAGAATAAAGTTGCCTAGAATATGAAAATTC +TAAACTTGCATGAAAGTAGTAAAACAGCCTCAAAATATATAAAAGCAAAAATTAAAATAA +TTACTAGCAGCAAAGACAAATCCACCATCGTAATGATTTTATAAATGGTACATTTACACA +AGTTGACCAAACACTGGTCAAAAAAGTAAGTTTTAACAAATTTGAAAAACTGGAGTCACT +TTCTCTGCTCTCAATACAATTATGCTAGAAATCAATAATAATTCTCATTTCTTTGAAAAT +TTAAAAGGTATTTCTATGTAACTCATCAGTCAAAAAATAATGGAATCTAGAAAACGGTAT +GAAAAAGTACGTGAAAAATTGGCACAGTTTTTCACATGAACGATATAACAGCATGATATA +ATCTTAAAAAGCACTTTAATTCTTGTGAATTAATTTATTTAATTGCCTGTAGTTCGTCTG +GCTTTAGTGCTTTTGTCATTCATAGAATACTCAATTAGCACAGTTCATAATCATGTATGC +TATGTATAAAAAAGTGACCAGTATTTTTTCATGATAATAAACCTGTTCTATCTCACTTTA +TACTTATGAATAATCTTCTCTGGCCGGGCTATTCCAAGGTATAAATTGTTTGAGTCAGTT +TGACATCTTAAAATTTTCCATCCTAAAAGTATTTATGATTCTTTGACCCCAATTCACATA +TCATTTTTTTAAACTGTTGAGTAACTGCATACACACATTTAAAAGCAATCTTGATTTGAG +TAGTTCCTATCTAAGGTCAAACACTTCAAAAATTGTAGGCCTAGTATGGCTAACAACATA +TCCTAGTAGCATATCTTTTGACAACAGGCAAGAAAGAGAATGAGAGCAGGAAGTATTAGT +GTATGGATATTGAGTCTTGGCTCCTAGAAACTGAGAAGTTAAAAGAAACACAGACAATGA +CATTCATTCACTCACTCACTCACTCTCCTCAGCTCTTTTCTCTCCACATGTCTGCATGCT +TCTTCTTTCTTTGGATCAGCTTTCTCTGTTCTCTAGTCTGCATGGCATATAATATGGCTA +CTCAAAGCCCTGAAATTTACAAGTTAAAGCCCCAGACATGTTAAGAGACTAATTCTCTTT +CTCCTGTTCCCAATTCCCAATTCCAGGGGACTTGGATTGGTTCCAGCTTTGTTCAGATGT +CTGTTCTCGTCTAATCAGCTGTGGCTAGGTGGAAAAGGCCACATAGTTTCCCACTGACCA +CTGCTTGGGTAGCAAGGGGTAGTAAAAGGTTTTGTTGTGAGCAAGAAATGGCATAGGTGT +ATCAGCAAGCAACATGTGCTACGTGTGTGCAACGTGCTTTCTGATGGAATCCTAACACCA +CCCTATGCCTGTTAGACAGGTGTCAAGTTGAATAATCAAGATGGACGGCATTGCCTGGGG +CTTTGTGTAGGGAAAGTGATACTATTTGGCACTGGACAAAGGTGTGGAGGGTAGATTTCC +TCAAGTAGCAAAAGACTGTACAGCAAAGAGACGTGTGGCCAGCACTGCCCCAAGAAGCTG +ACGGGTCACATCTGAACAGAAGCTGCCAAGTATACAACTGATACATGCTATTAGTATATG +TATATATACTATTAATATATGTGTATATATCATATAACTGATACATACTATTTACATTAT +CTTGAATGTACAGATTTAAATAATCAAAAGTGAGTATGGCAAAATAATGCATGATTAATC +CACCCATTTGCTCAACCTATAAATTCTAGCATAACCCTTTCTCTTCCCTATCTCCTTCCT +GCTTATTTACTTATCAATTCTTACTCCAAAATACCTTTTCAATTGGTTCCTTCCATTTCA +TCAACAATACCACGGTCTTAATTTGTCTTATTATATCTCTTTTCTAAATTTTTGCAATAG +CCTCCTAAATGACTGCCCTGCCTCCAAATCTCCAATATATTTTGTACTAGCTTCAATTTC +CATAATTTCTACTTTAAAGCAAGATCCTGTCCTTGTCACATCCCTGCTTATAAGTCTCTA +GTAAGTTCGTCACAGGCTACAGCAGAGGTCCCAAACATAAGTGCACATCAGAACCACATA +AATTTCTGGCCCTCATCCTAGATTTTCTCAATCAGAATCTCCTAGAATGGGGCTTAGAAA +TTTGTCTTTTTAACAAACTTCCCATTTGATTCTAGTAACCTGTCCAGCATCAATCTTTGT +ATCTGTGTTACAGAGCCACTGTTCTATAATATAAAGTCCAGACTCCCTGAATAGAACACA +AGTCAATTCACAATCTGATTCCAACCATTTTCTAGTCTCAGCCCCTGCAACTTTCCCTTC +TCAACCTTTCTCACAACACATTATGCCCTTTAAGACTGTCAGGTATCTATATATCTGCCT +TCTTCTCCTCTCTCGCCTTAGGGAACTTCTACTCATTCTGGGACAGAGTGAGACTCTGTC +TAAAAAAAAAAAAAAAGAATCAGTTCAATTGTCACCTACTCTGTGAAGCTTTCCTTGACT +GCCTCTAGCATTTATTCATTCCCTCTTGATTACAGAGTTGAAGAGACAGTATAGTGTGGC +CATTAAGAACACAGGTTCTGCAACTAGATTGCAAATGTTTGAATCTAGGCTCTGATAATT +TCTAATAAGTCAGTGAGTAACATGTGTACTTGGACAAGTTAATTGGTCTCTGTGCCTTAG +CTGCCTTCACTGAAAATGGGAATAATAACAGTGTGTGTCCAATATAAATTCTAAGGGTTA +ATGAGTTAATGTACAAAAAACAGTTGCTCAGACCCTAGCAAATGATCCTTAAATATTAGC +TTCGTGTTTAAGAGTTATTCCTGTCCCTTAGACTATGAACAAGTCTATTATATTAAGCCA +GTCAATTTAAGAGTTCCCCTTGTTAGTTGTGGTACCATAAATGAAGAAAAAAATAATAAT +TTAACAGAACTTATTTTCATCTCCTCAAAAGATGACTGAGGATAATGTACTAAACCTATT +TAAGAAAAAAAGCCATTTATGTGAGAAGGGCTTAGGTTATCTTTTTAAGTCATTCACTTG +ATAGGAAGAAACAATTTGGAAATCTTAGACAACTATTTGAATTTCAATGAAGAAAGAAAA +TATTAAACATAGCTCTGGGCTATTAAAACTGTATAAAGAACTGAAAAATCTAGAAAGAAA +TCTCACAGAACAAAATTCCTGTTATTATAAAACCAAAATTTTAGCCAAAAATATATCTCA +AGAAATCCTGTAGACTTTTAAAATGACTAGAAATAGAATAAAAACTTTTTATAAATCCTG +CCTTTTATTACTAAAGTCATATCTGAAATGGAAAAGATGGGGTAACGGAAAAACCTGGTC +ATCTGTAACAAAAGAAAACAGAGGCTGACGCAGGAGGATTGCTTGAGCCCAGGAGTCTGA +GACCAGCCTGGGCAAAATAGCAAAACCCCACTATAAATTTAAATTTATAAAATAAAAAAA +TAAATTAAAAATAATAAAGGAAAGCAAATTACGGTTATGTAAGGTAAGAAGTAAACAGGA +AAACTAAATTGGTGCTCAGATATAAAGTGAGCATCTTCTGTAATTTTCCGTTTTTCTTAT +TTTGCTTTGGAAATATTAGCTATTGAAACAAAATATAGTGAAATCTGGTAACAGGAGTCA +GCTCTTCTGCAGAACACATTTCTCCTTGGACGCATTCATTCACTCAAGTGTTTATTGAGC +AACTAATATTATACATGCTTGGATATAGCAATAAACAAAAGAGTCATTCAAGTGTGATGC +CATTCCTACAGTACTTATCATGTGAACAACATCGATATTCCAACAAGTTCCATGATACTT +TGTATACCTTTTATACTGACATAAGGTGCATATGGCTCCACCTGCAAATTATCACCATTA +GTGACTCCAGAAGAGTAAATCTATTTTGCTTCCATAGCATCTGACCTCCAGATCACGGGT +TTTTTTTACCTAGATTCAAGGATACCTAAAGGTTAATGGGTATATTGGGGGAAATCTGTG +AACTCCTTAATACTGCATGCCTATACTGTATTCTCCAGGGCCCCAAGACCCCAAGAAGAA +TTTTTTTAAAAATCAGTGCTCTACATGTAGAAAATTCTCTAGCTATTTGAGCAATTCTGT +CCTACTGAAAGGGCTGCTGCCATATACCAACACAGAGGATAGTTGGTAAACTCCTTACCT +GACATTTTATAGGACAATGTTCAACAATTTTATCATCAAGAAGTTATGTTTTGCTCATCT +AAATTCTGTCCTCTCCTGTTTTGAATACCAACAATCTAGTCAGTCTGTTAGACAAAGACT +TCTTCCAAAAAAACTGTTTACAGAACTTGGGCTCCAGCAACTTTTGCAATATAATCCTTG +TGCACTACTGAACCACAGAAAAATAACTCCTTAATTTGTGGTTGGAATAACCACTGCAGA +ACAACCTACAGTGGGTGGCATGAAACTATCACAATTATAAAGTAACCAAGCAAATAATAT +ACTAGGTCTCAAAGAGATAAAATGTTATAAATCCAAAACATACATTGCTATAAATAAAGT +CTGTGGTTATTTGCTGAGATGCTCTAACATTGCAGTAACAAGGGTTACTCTTAGCATGTT +TTATAAAGAAATAACTAAAGCTATTTGACAGTAGACTCAGTGGCACCACATGTATTGTTT +GGGCTAAGAAATTAGGTGAATTGCACTGTATAGTAACTTTGGAAAAATGCCGCCTTTAAT +ATAAACAAACAATGGACTTTCCTTTAGAAGCCACGAGAAGGGAGAGGAGGACAGCAGGAT +TTGTACTACCAAATCAGCATGCCAGCAATTTGGGAAACCATTGAATAAGAGCAATCAGTG +TGTCTAAATGCATATTTGTTGACAGCTGTAATCAGATCATTTCCTCAAAATTTAAATAAT +GGATTTTAGAGTTGGGAAGGCTCTTTAAGACCAACCAGACAATGGGGACTGAGGACTAAA +AAGGGTGCATGACTTGCTCAAGTTCACCAAACAGAACAGAAAGAAAGAACTGAGTCTCTT +GACTCCCTTATCAAGCTATCTTTCTTACACAGAAAGGTTTTTTTAATTAAAATATAATTC +ATGTGCTACAATTCACTAACTTAAATAAACAATTCAATGGCTTTTGGTATAGTCACTAAA +AACAGCTGTGCATTCATCATCACAATTTTTTAACATTTGTATCACCCCCAAAAGAAACTC +CCTTAGCTATCACTCCCTTAAATGTCCCCTACCCCACCCACTGCCTCCCATCTTCCCATC +CCTAGGTCACCACTAATCCATCTTCTGTCTCTACATACTTGACTATTCTGCACATTTCAT +ATCAAGGAATCATACAATATGTAGTCCTTTGTGACCAGCTTCTTTCACTGAGCATAATGT +TTTCAAGATTCAGACATGTTGTATCACGTCTTAGTACTTCATTACCTTTTTTTCTTTTTT +GAAATGAAGTTTTATTCTGCAACCCAGGCTGGAGTGCAGTGGTGCGATCTCAGCTCACTG +AAACCTCTGTCTCATGGGTTCAAGCAATCCTCCTGCCTCAGCCTCCTAAGTAGCTGGAAC +TACAGGTGGGAGACACGCCACCACGTCTGGCTAATTTTTGTATTTTTAGTAGAGACGGGG +TTTCACCATGTAAGCCAGGCTGGTCTTGAACTCCTGCCTCAGGATCTGCCCGCCTCAGCC +TCCCAAAGTGCTGGGATTACCGGTGTGAGCCACTGTGCCCAGCCCCATTACTTTTTAATG +GCTGAATAATATTCCACTGTATGGCAAGTTCCACATCTGCAATTTCCATACAGGCAAGTT +CCACATCTGCAATTTCTACATCTGCAGATTCAGTCAACCACAAATAGAAAATATTCAGGA +ATAAAAGCCAATAAAAATATAACAAAATATAAATAAAATTATCTGCATAGAATTTATCTT +ATATTAGGTATTATCAATAATCTAGAGATGATTTCAAGTATACAGGAGAATGTGTGTAAG +TATACCCAAGCACTATGCCATTTTATTAAAGGGACTTCAGCAACCATGGATTTTGGTGTC +TGTGGGGTCCTGGAACTAATCCTCCCACAGGTACTGAGGATACCTATACCCCATTTTGTT +TATCCATTCAGCAGTCGATGGACACTTGTATTGTTTCCACATTTTGGCTATCGTGACTAA +TGCTGCTATGAACATCTGTGTACAAGTTTTTGAGTCGACATCTGATTTCATTTCTCTTAG +GTATATATGTAGGAATGGAATTGCTGCATCATATAGTAACTCTGTTTAACCACTTGGGGA +ACTGCCAAACTGTCTTTGAAAATGACTGCACCATTTTACATTCACACTCATCGAAAAGTT +CCTGCTTTTAAAATCAAAACAATCAGATCACAAATTCCTTAGTTTCTGTTAACAGGTAAC +TGAAGAAAAAAACCCAAATATTGACACACGTTTTTTAAAAACCACATACTATCACTACAC +AAAACTCAGATTCAGAGTTCGAAACAGAGAAAGATAGCTTTAAATTGCTATTTTACAAAG +GATTACAGTATAGTGAATATTTCCTTAATTGCTGAAATCATATCAAAATATCACACAAGG +GCTATAGATAAATGTCAAACATTCAAAATATTGGGAGATCTTAAATATAAATTAAAAAGG +AAAAATTGATTGAATGCTCTCAAAAACCAAATTAAAATCTATTGCCAGGTGATTTTTACA +TACTTTCAGTCATTGGAAGGAAAACAAACATTTTTAAGATACAAAATTGATAGGTATTCA +ACAGGGCAAAGTAAATGCAGTATACTGGTTTGGAACACAAAATGAAAGCTAGCCACTATA +ACCATACAACAAAGAGTTATCGTCCAAATGGGCTTATGATAAGCAATTTGGGGAACAACA +ACTTTATACACAATGCAGTCAACTGTACATTCTGGATGTCAAGGGGTTCTGCTTCCATTT +ACTGGATAAGCTTCATATATATACATTTAGAGTTGGACTCTCAACACAGTGAAAGAGAGA +GAGAGAGAGTGTGTGTGTGTACATATATTTAGAGTTGGGATCTCACTGTGTTGCACAGGC +TGGAGTGCAGTAGCTATTTACAGGTTTGATCATACCACACCATACCCTCAGCCACGAGCA +GTGGTGTGTGCCTGAAGTCCTAGCTACTCAGGAGGCTGAGGTGGGAGAATCCCTTGAGCA +CAGCCTGGGCAACATATGAAGACACACCCCCATCTCCAAATAAATAAATAATGAAATTAA +AAAGCCAGCACATTATAGCCTCAAATTCCTGGCCTCAACAGATCTTCCCACCTCAGTCTC +CGGAGTAGCTACAACTACAGGCCTGCAACACCACGCCCAGCTAGGGTGTGCCTTCTACAA +AGGAAGGTTGGGGCAACTAGTAAGTGTAAAGTCGAGATTAAAAGAAAATTTGGCCAAGTA +TCAGCAACTCCCATGGGTGTTTCTGCCACTCAGAGACTCTAGAACTTTGGAACAGCAGCA +GGTAGACAAGTGGGTAAGAGGAAAGTGTGAATAGAAACAGAAAGAAAACGAGTTCTCACA +GAAAAGGGCCAGGAATAAATTAATAAAAAAAAAAAAAAGAAAGAAAGAAAGTGAAGAATC +TAAGCAGATACAAGTAGGTCGTGCATAGAAATCTAAACCTCTTATTTTATTATTTTTTAG +AGATAAGGGTCTTGCTATGTTGCCCAGGCTGATCTCAAACTCCTGACCTCAAATGATCCT +CGGCCTCACAAAGTGTTGGGATTACAGGCATGAGCCACTGCACCTGGCCTAGAAATCTGA +ATTTTTATCACATTTTCAGCACCAGCAAATTTGCCCTTTCTTTTCAGTGGTAGTTAAAAT +CTTCCAGAATTGTCTTTAGCTTTACTAATCTCCAGACAATGGTGGCTGATGAACTTTTTG +ACAGTACACCGAAGAAAGAACAGTTTATATCATAACTAGCACCCTCATAGAAATCTTTCT +AAACATATACATATAAACAAACGAGGCCGGCGCGGTGGCTCACGCCTGTTATCCCAGAAC +TTTGGGAGGCCGAGGTGGATGGATCACGAGGTCAGGAGATCAAGACCATCCTGGCTAACA +CGGTGACCCCTTGTCTCTACTAAAAATACAAAAAATTAGCCAGGCGTGGTGGTGGGCGCC +TGTAGTCCCAGCTACTCGGGAGGCTGAGGCAAGGAGAATGGCGTGAACCCGAGAGGCAGA +GCTTGCAGTGAGCCGAGATTTCGCCACTATATTCCAGCCTGGGCGACAGAGCGAGACTCT +GTCTCAAAAACAAAACAAAACAAAACAAAATAAAAAAACAAAAAAAAAACAAATGAAATG +TTCCCCAAAAGCACTAGTCTTGCTATTTTGGTACAGCCTAGTATTTTCTATTCTATTTCA +TATTTTTAAAAAAAGCTGAAAATGGCCCAATAAATTATGATGTGCAGTTTTTCAAGGATA +AAGCTCATAGGAAATGATGATAATATAATCAACCATGACTAACTTCAGATACGGGCAGGC +AATGACAAACTACATCCTAAGTGTCACCTGGCCAATAGTAATTTCAAAGAGGTAGGGCAG +GCTAAAATACAAAAAAAAGTTTGTCTCATAGTCAACAAAATTAGGTAATAAAAGCTCAAT +AAATGAATATTAGTTCACAAATATTACATTTTTTATTATTATTACGGAGGGCAGTAGGAA +TCCTGACTTAATTCTAAAATAAATTTCAAGTAATTTCAAATAAATAAGGCTAGGCACAGT +AGCTCACACGTATAATCCCAGCACTTTGGGAGGTCAAGACAAGAGGACTGGCTGAGCCCA +GGATTTCAACATCAGCCTGGGAAACATAGTGAGACAACCCCCACCCCATCTCTACAGAAA +AATGTACAAAAATTAGCCAGGTGTGGTGGCATGCACCTGTAGTCCCAGCTACTTGAAGGG +CTGAGGTGGGAGAATCACTTGAGCTTGGGAGGTTGAGGCTGCAGTGAGCTGTGGTCATGC +TACTGCACTCCAGCCTGGGCAACAGAGCAAGACCCTGCCTTGGAAAAGATAATTAATTAA +TTAACACTGAAATATACAACTATAAAATACTAGAGAGAAACACAGACCACTACTTTTACA +AAGGCAAAAGCCTTTGTAAGTATGTAAGTATGGTACCCAAACCAGAAATTATAAAAGAAA +AAGGCAAATGAATTACATAATACAAAAATTTTGTATGGCAAAGTAATCAACAACAAACTG +GAGTAAATTTTTTTTAACAGTTACAACAAAGAGTATAAACTAACAAGAAAGTGATAAATA +CAAAAGACTAATGAGCAACCAGAACAGGCCAATGACTCTGGAGTACAAAATTCATTTAAG +AATTAAATAAACGGCCAAACGTTCAACATTGCTAGTCATCAAAAGTGCAAATTAAATCAA +TAATGTAATAACTTTTGCTTATTAGATTGGCAAGATGAAAAAAAAACACCTAGTGTTGGA +GAGAGACAGTTACTTTGGAAATTTGAGAATGTGTATAAATCTTTAAAGAATGTACAACCA +ACCTATCCAGTTCCTCCACTCTAAATAATTTATTATAAGGAAATAATCAGATAGTTATAC +CAAAATCTATATACAGATAAAAATAATAAAAACTGAAAACAACATCAATATATATTAACA +GGGAATTAGTTAAAGAAGTTGTAGTAGTAAAATGCTATGCAGTCTTTAACAATTTTGTTT +ATGACATAGTTAGCTGGCCCTGACATATGTTTATTTGGGAAGGCGGGGGAAGACCTACTT +ATGAGGCAGTATGCAAAAATACTGGCAGATTTCTGTTGTTGTTAAGAATCTTTTTTTTTT +TTTTCCAGACCAAGTTTTGCTATTGTTGTCCAGGCTGGAGTGCAATGGCGCAATCTCAGC +TCACTGCAACCTCTGCCTCCCGGGTTCAAGCAATTCTCCTGTCTCAGCCTCCCAAGTAGC +TGGGATTACAGGCATGTGCCACCAAGCCCAGCTAATTTTGTATTTTTAGTAGAGACAGGG +TTTCTCCATGTTGATCAGGCTGGTCTCAAACTCCTGACCTCAGGTGATCTGCCTGCCTCG +GCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCACCCGGCCTTGTTAAGAACCT +TTTTTAAAACATATATATAAAAATGCTGGCTGAGTTCCATGGCTCATGCCCATAATCCCA +GCACATTGAGAGGCCAAGGTAGACGGATCTCTTAAGTCCAAGAGTTCAAGACCAGTCTGG +GCAACATGGCGAAACCCTAGCTCTACTAAAAATACAAAAAATTAGCTGGGCATGGTGTCA +TGCACCTGTAGCCCCAACTACACGGGAGGCTGAGGTGGGAGGATTGCTTCAACCAGGGAG +GTGATGGTTGCAATGAGCTGAGATCGCGCCACTGCACTCCAGTCTGGGCAACAGAGTGAG +ACTCTGTCTCAAAACAAAAGGAAAAGAAAAGAAAAACAAAAAGAAAATGTTTCACTTGGT +GATAATTGTTTTTTTCCTTCATTTGAATTTGTATTTTGCAATCAGCTTAAATTACTTTTA +AAATAAAATGATATTTTTCAAATAAAAAGATGAACAATCTTAATGCTCAATCTGTTTACA +TAAACCTGAAAAATATTAATAACCTTTAAGCCTACTTGCTCCACTTAATCTTTCCTCAGG +AAATAATCCTAGAAGTCTTAACCACAGAGATGTTCCAGACTGTGTCATTTGTAAGAGTGA +AAAAGTAGTAACAACCTACCTAATAAACAGGAATGCCTGAAGAAATTATGATATATTCAA +TGATATATAGTGCATCCTTCATAATGAAAAAAATGCTACACAATAAACTTCAGTGAGAAG +CTCAATATTCAAAATTATAGAGAGTATGATTAAAACCATATTATGTACAAACAAAACAGA +AATCTGTAGCTGAAAAGATTGGAGGCAAATGTACTAAAATGAGTGGTGGAGCTCATTAAA +TACTCATTTAAATGAGTATTTTAAAATTTAAATACTTAGAGAATTTCCCACAGCTTCTTT +ATGAAAATGCATTAGTTTTACAAATTGAAACCAAAAAATAATAATAACAGAAATATCGAC +ATAAATCCAATTTTACTAATTTGGCTTGATCACTGAAAAATATCAACTTTGACAGCTCAG +TGATCAATACATAGAATAAACAAATGATTTAAAGCTTTAATCTAAAATGAAGAGACCAAC +AGAATTAATTAAGTTTCCTTTGATCAATAAATTATTTTTATAATAAACAAAAGAATACAG +GCGAAGCACAGTGGCTGTCACCTGCAATCCCAGCACTTTGGGAGGCCAAGGTAGGCAGAT +CACTTGAGACCAGGAGTTCGAGACCTGCCTGGCCAACATGGCGAAATCCCATCTCTACAA +AAAATACAAAAATTAGCCAGGTGTGGTGGTGGATGCCTACAGTTCCAACTACTTGGGGGA +CTGAGGTGGGAGGATTGCTTGAACCCGGGAGGCGGAGGTTGTGGTGAGCTGAGATTGCAG +CACTATACTACAGCCTGGGTGACAGAGTGAGACTGTCTCAAATAATAATAATAATAATAA +TAATACATAAAGATATATGTATAGGAAGAAACACTTGCATAAATAGAATTTTAATGTAAA +AACACCATATTTTATATTTATGATATATAAATACTTCTTTTTCCTATTTCCCTTTTTCTT +ACAAAAAATGCAACTAGAACTATTTGCTTGGTTAATTATCCAATTTAAAAAAATAAATAT +GAAAATAGAAATGTAGACAGATCACATCATAATGTAATTAGTTAAAAAGACATGCTTTGG +AATTCAGATTAGGAAAGACAATATAAGAACAGTCCATCTATTTATTAGAGACTGACAGCT +TATGGTTGACAATGGTGTGGCTGAATTTAAGTGAACTTAATTAAATATTACTTGATAATA +CTTAACAGTAAAGTGATAGGGTGAAACAAATTGCAAAGTGTGGGCTAAGGTGAACTAGGC +TTATACTTAATGTTTTTTAATTCTTTTACAAAAGATTATTGCAACAAAAAGATGTTAAAA +TTTTTAGAAAGTGACAGTTGTATTTTTTTTTTCCCTGATAAACATGTAATCTAAGTAGTT +TAAAACAACTAGGAAGATAAGAATCTGTCCGAAGTGACAGACTGATCAGGATTTCATCTT +CACCATGCATTGTGGATCAGATCAGGCTTCAATACAAAACTCTACTGTGTACTAGCTCAC +GACTTTGCATATATTTCATACCTTCTCTAGGTCTCAGTTTCCTTGTCTAAAAACTGTGGA +TAATGTTTCCTAACTTAGAGCATTACTATATTTATCCTTGAAAAAAGACAGGATATAAGA +GTAAGCTATGGTTATATTTTTGACAATTGAAAAGAGAATTTGGATTATGATCTTAATTTT +ACCCACTCTTCACTCCACCCCCATCTCTACAAAAACAAAACAAAATAAATAAATAAATAC +GCAGTTTCCAAGAATTGTGACATAATTTTATTTTCCAGAAAATGAAATCAGTGGATAACC +ACCCCTTAGGAAATGAGCATAGAACAAACTCATTTTACATGAGTTAAAATGTAGTAATCA +GAATGGAAAGAGGCAAGAACATATTACTTTAATGATGTATTTTTTTTCACTATTGAAAGT +TGAAAAGTGTTATCAGAAATTCTCTGAAACAAACATATCTTAGTAGTCATTTCTAATATA +AAATACATTCAGTCACTAATTTTTTGTGTTGTTTTGTATCTTTAGTTGAAGACAGGAACA +CATAACCTATACTTTCAAAATACAGCCAGCCTAAAAAGGTAAATAAAATTTTTTATTTTG +AAAAGGGAAAAATTTCAAGAAAAAAACTGTACCTATCTGTAGATGCTGGATAATGTTCAT +TCAAATCTTTATAATACGGGAGCCTTTATTCTTTGAGAGGCAGAACTGGAGAATTAGGAC +TTTGGAGGAAGAGACATCTGAGTTAGAATTCCAGCTTTGCCACTTAATAGTGGTGGGAGC +TCAGGCACAGCAGCAGAACCCACTGGCTAGGTGACACAAGAGTTATATTCCCAGTCTCCT +TCTCACCTGAAGCAGCCACAATGAAAAAGTTAAACACTGATTTTCAGAGCCTTCCCTGCA +GTTAGGGAGAAGCTAGATATGTTGTATAGGTCTGACCAATTAAATGAAAACTGAAGTCTG +GCAGCTTTTGTTTTCCTGGTAAAAGGGACAAAAAAATAAAAAATAAATTTTAAAAGAAAT +TTTTTTACTTATTTATTTCTTCTTGTGAGACAGGGTCTTACTCTGTCACCCAGGCTGAAG +TGCAGTGGCACAAACACAGCTCACTCCAGCTGCAACCTTCCGGGCTCAAGAAATCCTCCT +GCCTCAGCCTCCCAAAATGCTGGGATTACAGGTGTGAGCCACTGCACTCATCCCAGGTCT +GCTTTTTAACTACCCTTATGAAAACTACCTGCCCTCCCCAATCTCTTCCTTCCCATTCTC +TTCCTCCCTTAAACACAGACATGTGGTCTGTAGAATCAGCAGCCTTACTGTACCATGCAT +GACTCAAGAAGCCCCAAGCCTCATGTTGATGTTAAAGCATAAAGCATTGTCAAGCTGCTA +AAACAACCCCAGTAGCCACTAACATTCAGGATTCTCACGCAAAAAAAAAAAAAAAAAAAA +AAAAAAAAGTCTCTATCTTTTTAAGCCACAAGTAGACAAGTTTTCTGCTATTTGCAATTG +ACACAAGTCTAAATGATTTGGAAAGTCACAAATTCTGAGAATCACCTTCCTCATCTATTA +AATAAGGGTGATGCTAGTAAGACGTATGTAAAGCATAGTATCTGTCTGACACATAGAAAA +GGTTCAATAATGCCAGCTGTTGTGATAATGATGACAACTTTAATTCTCACACCAACCAGT +ACTTTGATAGCACTTTGGGGGTAAGTACTATCTTCAACCACTTTAAAGACAAGAAAATTA +AGGCTCCAAAGTTAAGCAACTTGCCTAAGATCACACAATTAGTTAGGAGTAGAGCCAGGA +TTCAAATCCAGAAATCTTTCCAAGGCCATGATCTTAACTAGTATTATGCTTAGAAAAGTG +ACTGAGTACAATTAAGACTTAACAGCTAATAAATGTTGGCTATAATGATTATGACAACAT +AGCCAACTATGAAGACAAGAACAGGCAGAAAATGCCCTATAGTTTTCAAATCTAGAAAAC +AATAAATTCTCATTTAATTTGACATTGATTTTGTTTGACATTGATTTTATTTTTCTTAAA +ATTGAAATGGCTCTCATTTCTTCACTAAAACAGGTTACTACAGCCTCTTCACTGGAGGTT +AACTTCATCCCTTTGTAACACCAAAGGAACTAAGAACAGTATATTCAACCAATAATTGAA +ACACCCTACCAATAGGTAAATGACTTGGTGACTCTTGTCCATCAAAAAAGTAAGCAATGA +GTATTTATTGTGAACTTATACTCTGCAAGGCACTATGCCGGACATTTAAAAATTATTTTC +TCCAAAATATGCAGCACATGTTGATTTTCTTAAAGTGACTTAAGATTCCTTTGGAGGGAA +AATTTAATAACAATTTAAAACATTAGGAAGATGCTGCTGCTGCTACCAGTCATCAACACC +ATCGTCACCATCACTACCATTACTATTAATAATAGAATTCATATCACAAATCAACATATG +CTAAACTTTACTTTTGGAATGCTTTGCTTCAAACTTCAGATGTCCTCTTCAGTGAAATAA +ATGAAACAAAGAGCTTTAAAAATTCATGCTGGGTCGGGCGCAGTGGCTCACACCTGTAAA +CCCAGCACTCTGGGAGGCCGAAGCTGGCAGATTGCTTGAGTTCAGGAGTTCAAGATGAGC +CTGGGCAATGTGGTGAAACTCTGTCTCAACAAAAAAATACAAAAATTTGCTGGGCATGGT +GGCATGCACCTGTAGTCCCAGCTACTTGCAGGGCTGAGGTGGGTGAATCGCTTGAACCCA +GGAGGTGGAGGTTGTGGTGAGCTGTGATCACTGCACTCCAGCCTGGGCAACACAGCGACA +CCCTGTCTTAAAAAACAAAAACAAAAACATGCTGAAGACACAGTATTTAAAAAACAAGCT +AAATTCAAAATTAAAGTTTCTAAATAAATTACGTTCAGGAAACAGGCAAACTAAAATATT +TGCAATTGCAGTTAGGAAAGATATTTAGTTTCTCAAATAGATTTTGAGATTTAAAGAGTT +TGTGTTTAGCTGTTAACTTTCAAACTAATATGATGTATTATCATTCTAGTAAATAAAAAA +AGTAAAATAAAAACTGAAACAGAATGGTAAGTAAAATAGAAGTTTTGAGGTAAGACTAAC +TCTAGTAAAAATGCTGAGTCTGAAAATATGTACGTTTACAGCAATATATTTTGGAAGCCG +AGTAACTTAAAATCGTATCTTCCACACTGAAAGAGGTATAGCATAACAAAGAGTTGACAC +TACTATAAGTAGATATAAAAGAAATGCTTTCAAGGAAATCACATCAAGGAAGGATTGGTT +TGCTTAATAAATTCAAAAATGACAGAGAGTAGCATAAAATCCACATGAACATTATAATAT +GCTCAATCAGTTCTAATTAAGGATTTAATTATACCTATTTGATATCTAATTTGCATTTTT +CTAAAGGAACACGAAGTATTCTATTTTAGGTCCAAAGTTAAGGCTCTGGGCAGGGTGCAG +TGGCTCATGCCTGTAATCCCAGCACTTTGGGGGGGCCAAGGCAGGTGGATCACTTGAGGT +CAGAAATTCAAGACCCGCCTGGCCAACATGGTGAAACCCCATCTCTACTAAAAGTACAAA +AATTAGGTGAGCATGGTGGCGGATGCCTGTAATCCCAGCTACTCAGGAAGCTGAGGCAGG +AGAATTGCTTGAACCCAGGAGGCAGAGGTTGCAGTGAGTCAAGATCGCACCACTGCATTC +CAGCCTGGGCAACTGAGTGAGACTCCATCTCAAAAAAGAAAAGAAAAGAAAAGAAAGAGA +TGGTGGAGCCAAGATGGCCAAATAGGAACAGATCCGGTCTACAGCTCCCAGCATGAGCGA +CGCAGAAGACGGGTGATTTCTGCATTTCCATCTGAGGTACTGGGTTCATCTCACTGGGGA +GTGCCAGACAGTGGGCGCAGGACAGTGGTTGCAGCGCACCGTGCGTGAGCCGAAGCAGGG +CGAGGCATTGCCTCACTCGGGAAGCACAAGGGGTCAGGGAGTTCCCTTTCCTAGTCAAAG +AAGGGGGTGACAGACAGCACCTGGAAAATGGGGTCACTCCCACCCTAATACTGCGCTTTT +CCGACGGTCTTAAAAAACGGCGCACCAGGAGATTATATCCTGCACCTGGCTCGGAGGGTC +CTATACCCACGGAGTCTCGCTGATTGCTAGCACAGCAGTCTGAGATCAAACTGCAAGGCG +GCAGCGAGGCTGAGGGACGGGCACCCGCCATTGCCCAGGCTTGCTTAGGTAAACAAAGCA +GCCGGGAAGCTCGAACTGGGTGGAGCCCAACACAGCTCAAGGAGGCCTTCCTGCCTTTGT +AGGCTCCACCTCTGGGGGCAGGGCACAGACAAACAAAAAGACAGCAGTAACCTCTGCAGA +CTTAAATGTCCCTGTCTGACAGCTTTGAAGAGAGCAGTGGTTCTCCCAGCACACAGCTGG +AGATCTGAGAACAGGCAGACTGCCTCCTCAAGTGGGTCCCTGACGCCTGACCCCCGACCC +CCGAGCAGCCTAACTGGGAGGCACCCCCCAGTAGGGGCAGACTGACACCTCACACGGCCA +GGTACTCCTCTGAGACAAAACTTTCAGAGGAACGATCAGACAGCAGCATTCACGGTTCAA +GAAAATCCACTGTTCTGCAGCCACCGCTGCTGGTACCCAGGCAAACAGGGTCTGGAGTGG +ACCTCTAGCAAACTCCAACAGACCTGCAGCTGAGTGTCCTGCCTGTTAGAAGGAAAACTA +ACAAACAGAAAGGACATCCACACCAAAAACCCATCTGTACATCACCATCATCAAAGACCA +AAAGTAGATAAAACCACAAAGATGGGGAAAAAACAGAGCAGAAAAACTGGAAACTCTAAA +AAGCAGAGCGCCTCTCCTCCTCCAAAGGAACGCAGCTCCTCACCAGCAACGGAACAAAGC +TGGACGGAGAATGACTTTGACGAGTTGAGAGAAGAAGGCTTCAGACGATCAAACTACTCC +GAGCTACAGGAGGAAACCCAAACCAAAGGCAAAGAAGTTGAAAACTTTGAAAAAAATTTA +GACGAATGTATAACTAGAATAACCAATACAGAGAAGTGCTTAAAGGAGCTGACAGAGCTG +AAAGCCAAGGCTCGAGAACTACGTGAAGAATGCAGAAGCCTCAGGAGCTGATGCGATCAA +CTGGAAGAAAGGGTATCAGTGATGGAAGATGAAATGAATGAAATGAAGTGAGAAGGGAAG +TTTAGAGAAAAAAGAATAAAGAGAAACGAACAAAGCCTCCAAGAAATATGGGACTATGTG +AAAAGACCAAATCTATGTCTGATTGGTGTACCTGAAAGTGACGGGGAGAATGGAACCAAG +TTGGAAAACACTCTGCAGGATATTATTCAGGAGAACTTCCCCAATCTAGCAAGGCAGGCC +AACATTCAGATTCAGGAAATACAGAAAACGCCACAAAGATACTCCTCGAGAAGAGCAACT +CCAAGACACATAATTGTCAGATTCACCAAAGTTGAAATGAAGGAAAAAATGTTAAGGGCA +GCCAGACAGAAAGGTCGGGTTACCCACAAAGGGAAGGCCATCAGACTAACAGCGGATCTC +TTGGCAGAAACTATACAAGCCAGAAGAGAGTGGGGGCCAATATTCAACATTCTTAAAGAA +AAGAATTTTCAACCCAGAAGTTCATATCCAGCCAAACTAAGCTTCATAAGTGAAGGACAA +ATAAAATCCTTTACAGACTAGCAAATGCTGAGAGATTTTGTCACCACCAGGCCTGCCCTA +AAAGAGCTCCTGAAGGAAGCACTAAACATGGAAAGGAACAACCAGTACTAGCTACTGCAT +AATCATGCCAAATTGTAAAGACCATCGAGGCTAGGAAGAAACTGCATCAACTAACGAGCA +AAACAACCAGCTAACATCATAATGACAGGATCAAATTCACACAAAACAATATTAACCTTA +AATGTAAATGGACTAAATGCTCCAATTAAAAGACACAGACTGGCAAATTGGATAAAGAGT +CAAGACCCATCAGTGCGCTGTATTCAGGAGACCCATCTCATGTGCACAGACACACATAGG +CTCAAAATAAAGGGATGGAGGAAGATCTACCAAGCAAATGGAAAACAAAAAAAGGCAGGG +GTTGCAATCCTAGTCTCTGATAAAACAGACTTTAAACCAACAAAGATCAAAAGAGACAAA +GAAGGCCATTACATAATGGTAAAGGGATCAATTCAACAAGAAGAGCTAACTATCCTAAAT +ATATGTGCACCCAATACAGGAGCACCCAGATTCATAAAGCAAGTCCTGAGTGACCTACAA +AGAGACTTAGACTCCCACTCAATAATAATGGGAGACTTTAACACCCCACAGTCAACATTA +GACAGATCAATGAGACAGAAAGTTAATAAGGATACCCAGGAATTGAACTCAGCTTTGCAC +CACGCGGACCTAATACACATCTACAGAATTCTCCACCCCAAATCAACAGAATATACATTT +TTTTCAGCACCACACCACACCTATTCCAAAATTGACCACATAGTTGGAAGTAAAGCTCTC +CTCAGCAAATGTAAAAGATCAGAAATTATAACAAACTGTCTCTCAGACCACAGTGCAATC +AAACTACAACTCAGGATTAGGAAACTCACTCAAAACCGCTCAACTACATGGAAACTGAAC +AACCTGCTCCTGAATGACTACTGGGTACATAACGAAATGAAGGCAGAAATAAAGATGTTC +TTTGAAACCAACAAGAACAAAGACACAACATACCGGAATCTCTGGGACACAGTCAAATCA +GTGTGTAGAGGGAAATTTATAGCACTAAATGCCCACAAGAGAAAGCAGGAAAGATCCAAA +ATGGACACCCTAACATCACAATTAGAAGAACTAAAAAAGCAAGAGCAAACACATTCAAAA +GCTAGCAGAAGGCAAGAAATAACTAAAATCAGAGCAGAACTGAAGGAAATAGAGACACAA +AAAACCCTTCAAAAAATTAATGAATCCAGGAGCTGGTTTTTTGAAAGGATCAACAAAATT +GATAGACCGCTAGCAAGGCTAATAAAGAAGAAAAGAGAGAAGAATCACATAGACGCAATA +AAAAATGATAAAGGGGATATCACCACCGATCCCACAGAAATACAAACTAACATCAGAGAA +TACTATAAACACCTCTACGCAAATAAACTAGAAAATCTAGAAGAAATGGATAAATTCCTC +GACACATACAACCTCCCAAGACTAAACCAGGAAGAAGTTGACTCTCTGAATAGACCAATA +ACAGGCTCTGAAATTGTGGCAATAATCAATAGCTTACCAACCAAAAAGAGTCCAGGACCA +GATGGATTCACAGCCGAATTCTACCAGAGGTACAAGGAGGAACTGGTACCATTCCTTCTG +AAACTATTCCAATCAATAGAAAAAGAGGGAATCCTCCCTAACTCATTTTATGAGGCCAGC +ATCATCCTGATACCAAAGCCTGGCAGAGACACAACCAAAAAAGAGAATTTTAGACTAATA +TCCTTGATGAACATTGATGCAAAAATCCTCAATAAAATACTGGGAAACTGAATCCAGTAG +CACATCAAAAAGCTTATCTGCCATGATCAAGTAGGCTTCATTCCTGGGATGCAAGGCTGG +TTCAATATACTCAAATCAATAAATGTAATCCAGCATATAAACAGAACCAAAGACAAAAAC +CACTTGATTATCTCAATAGATGCAGAAAAGGCCTTTGACAAAAATCAACAACCCTTCATG +CTAAAAACTCAATAAATTAGGTATTGATGGGATGTATCTCAAAATAATAAGAGCTATCTA +TGAAAAACCCACAGTCAATATCATACTGAATGGGCAAAAACTGGAAGCATTCCCTTTGAA +AACTGGCACAAGGCAGGGATGCCCTCTCTCACCACTCCTATTCAACATAGTGTTGGAAGT +TCTGGCCAGGGCAATTAGGCAGGAGAAGGAAATAAAGGGTATTCAATTAGGAAAAGAGGA +AGTCAACTTGTCCCTGTTTGCAGATGACATGATTGTATATCTAGAAAACCCCGTTGTCTC +AGCCCAAAATCTCCTTAAGCTGATAAGAAACTTCAGCAAAGTCTCAGGATACAAAATCAA +TGTGCAAAAATCACAAGCATTCTTATACACCAATAACAGACAAACAGAGAGCCAAATCAT +GAGTGAACTCCCATTCACAATTGCTTCAAAGAGAATAAAATACCTAGGAATCCAACTTAC +AAGGGATGTGAAGGACCTCTTCAAGGAGAACTACAAACCACTGCTCAACGAAATAAAAGA +GGATACAAACAAATGGAAGAACATTCCATGCTCATGGGTAGGAAGAATCAATATCATGAA +AATGGCCATACTGCCCAAGGTAATTTATAGATTCAATGCCATCCCCATCAAGCTACCGAT +GACTTTCTTCACAGAATTGGAAAAAACTACTTTCAAGCTCATATGGAACCAAAAAAGAGC +CCACATCGCCAAGTCAATCCTGAGCCAAAAGAACAAAGCTGGAGGCATCACGCTACCTGA +CTTCAAACTATACTACAAGGCTACAGTAACCAAAACAGCATGGTACTGGTACCAAAACAG +AGATATAGATCAATGGAACAGAACAGAGCCCTCAGAAATAACGCCGCATAGCTACAACTA +TCTGATCTTTGACAAACCTGACAAAAACAAGCAATGGGGAAAGGATTCCCTATTTAATAA +ATGGTGTTGGGAAAACTGGCTAGCCATATGTAGAAAGCTGAAACTGGATCCCTTCCTTAC +ACCTTATACAAAAATCAATTCAAGATGGATTAAAGACTTAAATGTTAGACCTAAAACCAT +AAAAACCCTAGAAGAAAACCTAGGCATTACCATTCAGGACATAGGCATGGAAAAGGACTT +CATGTCTAAAACACCAAAAGCAATGGCAACAAAAGCCAAAATTGACAAATGGGATCTAAT +TAAACTAAAGAGCTTCTGCACAGCAAAAGAAACTACCATCAGAGTGAACAGGCAACCTAC +AGAATGGGAGAAAATTTTCACAACCTACTCATCTGACAAAGGGCTAATATCCAGAATCTA +CAATGAACTCAAACAAATTTACAAGAAAAAATCAAACAACCCCATCAAAAAGTGGGCAAA +GGACATGAACAGACACTTCTCAAAGGAAGACATTTATGCAGCCAAAAAACACATGAAAAA +ATGCTCACCATCACTGGCCATCAGAGAAATGCTAATCAAAACCACAATGAGATACCATCT +CACACGAGTTAGAATGGCAATCATTAAAAAGTCAGGAAACAACAGGTGCTGGAGAGGATG +TGGAGAAATAGGAACACTTTTACACGGTTGGTGGGACACTAGTTTAACCATTGTGGAAGT +CAGTGTGGCGATTCCTCAGGGATCTAGAACTAGAAGTACCATTTGACCCAGCCATCCCAT +TACTGGGTATATACCCAAAGGACTATAAATCATGCTGCTATAAAGACACATGCACATGTA +TGTTTACTGCGGCTCTATTCACAATAGCAACGACTTGGAACCAACCCAAATGTCCAACAA +TGATAGACTGAATTAAGAAAATGTGGCACATATACACCATGGAATACTATGCAGCCATAA +AAAATGATGAGTTCATGTCCTTTGTAGGGACATGGATGAAACTGGAAATCATCATTCTCA +GTAAACTATCGCAAGAACAAAAAACCAAACACCGCATATTCTCACTCATAGGTGGGAATT +GAACAATGAGAACACATGGACACAGGAAGGGGAACATCACACTCTGGGGACTATCGTGGG +GTGGGGGGAGGGGGGAGGGATAGCTTTAGGAGATATACCTAATGCTAAATGACAAGTTAA +TGGGTGCAGCACACCAGCATGGCACGTGTATATGTATGTAACTAACCTGCACATTGTGCA +CATGTACCCTAAAACTTAAAGTATAATAATAATAAAATAAAATAAATAAAAATAAAAAAA +TTAAAAAAAGAAAGAAACCTAACTGTGATATATTTATGGAAAAATATTTTATTAAAAATT +AAAACAAGGTAAGAACAAAGCATCATGTTTTCAAGTATAGGACAATGTTGAACCTAAATA +ATTCCTAATATATTCAATAAAAGAAAAATGGATATGTATAAATGGAGACATAAAAAACAC +AAATGTCATTTATAGACACATAAAAGTATTCTTTAATTATTATAGTGCTGTGATTTTTAA +AACAGACAGCTCCAAAATAAGCCTTTTTGAACAATTCTGTTCATCAGACTCCTGGGTAAA +TGAATTTCTACTGTACACACTGACAGATACAGGGTTAGAACCTAGATCTCTTGCCCTCCA +CTCCTATGTTCTTCCTGTTACTTGTCTTGCTTGACTTCCTTGCACATGCCAAAAACTACT +GTATCTGCTTCCTGCCATTTTTACCCTCTAAAATTGTATAAAGCACTTCCTAGAAGAATA +TAGAAAAAGAACAGAGAAGTAGAAGGAGAATCAAGAAAATAAAGGTATGTGACAATTTCT +GAGAAGGGAATAGCCAATATTATTGAATAATACAAAGCAGTTAAGCAGAAACTAGTGGGC +AGGTAACCAGATGTCCCTGATGAGTTTAAGAGGGTGCTTTCAACAAGTATAATGGTGAGG +GCAGAGCCTGGTGGGCTGAACTGATGAATGAACGGTAATTTGGGAATGGGAAAAGTACAA +TAGTTTTAAGGGGAAACATGCTAAAATGTTTGCAATCTTACCAAACTATCTAGAAAAAAT +GATATAGAAAAAATTTAAGGTAAGAAATAGGAAATCCAGGGAGTATTAGCTTGAATCAGT +TGAAATTTCAGATACTCAACTATTTTGACGTTAAAAGCTGCAATTTTATACGGTTTAAAC +TAAGGTACAAACTTGATTTCAAGAAAGGAGATAAGGTTATCTTCTAAGGACATAGAAGCA +AAGAACAGATGCCTAAGAGTGAAGTAGGTAAAGTAATAAGAAATCTACGAGAAATGAATG +AAAGAATTTTAGAGTCCTGAAGTTGAATAATAAGAATAATATACTTGGCAAAGCTACACT +GTTTTTCTAAAAGGATCCTGTTATTTTTACATTTGCATTTCACTTTTAGAAATTTAGCTT +TTTTTCTGTAATAGGATGCCTGAACATGAACCCCGCAACATTTCTTCAAGGCAGGCACTC +TCACTTAATGTGGTACAAACATAACTGCAGTGATGCTGTTGCCTTTATATTTTGTTTTGT +TTTGTTTTGTTTTTGCTGATAAAGGCAGAAGATCAAGGCACTTAGAGCCTAATATGAAGT +TGCTATTAACAATCCCAGGTCTACTGTTATTCCACAACCTAATTTCTCATATTTCCAATC +CCATGTCACCAAATGCCTACAGAAAAATCACAACATGACCAGGCACAGTGGCTCACACCT +GTAATCCCAGCAGTTTGGGAGGCTGAGGTGGGTGGATCACCTGAGCTCAAGAGTTCAAGA +CTAGCCTGGGCAACATGGTAAAACTCCACCTCTACCAAAAACACACACAGACAACATTAG +CCAGGCATGGTGGCAGACGCCTGTAGTCCCGGCTACTCAGGAGGCAGAAGCACAAGAATC +GCTTGAGCCCAGGAGGTGGAGGTTGCAGTGAGCTGAGATTGCACCACTGCATTCCAACCT +GGGTGACAGAGTGAGATCCTGTTTCAAAAATAAATAAATAAAGATAGAATAACCATAACA +TGTCTAAAACAGAACTCCTGCCCTTTGAACAGTTCTCTACCCCACTTCCCTACGGCTGTG +ACCTCTATTTTTCTAGTCACCTGGGCTAGAAACCTTTAGCATGAGTTACCGAGTCCTATC +AGTCTTTCTCTGAACAGGCTCTTCTAGCTTTCTGTTCCCATCTCTTTCCACTCTAGTCCA +GCCTCTAATCACCTCTTGTCTGGATTACAACAGTCTCAGAACTGGTCTTATGGTATCCAC +TCCATCTCACACATCACTACTAATGTCAGCATACAAAAATGCCAATCCCCAAACACCACC +ATCATAACTTTTCACCCTGAAATTCAGACTTATCTATAAGGATACTAGCCTATCTAGCAA +AGCAAATATTTCACCACTCCCTAAAACTTCCATGTCATGGAATCTTGACCACTGTGGTCA +CTTTAAATGCATACACAGCAAAAAGAAAAAGAATAGAATAGAGGAGCAAAGAGAATGGAA +ACAAAGACAATGATTAGGAGAAAGTCACTGTGGGATAGGCGCAGTGGCTCATGTCTGTAA +TCCTAGCACTCTGGGAGGCCGAGGCGGGCAGATCATGAGGTCAGGAGATTGAGACCATCC +TGGCCAACATGGTGAAACCCCATCTCTACAAAAAAAAAAAAATTCAAAATTAGCTGGGCA +TGGCGCGCGCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGTAGGAGAATTTCTTGAAGCC +CAGAGGTGGAGGTTGCAGTGAGCCAAGATCATGCCATTGCACTCCAGCCTGGTGACAGAG +CAAGACTCCATCTCAAAAAAAAAAAAAAAAAGTAACTGTGGCAAATTCAGGTACAAGGTA +CAAGATATCCATGGCTGGAGAAAAGCCCTAATGGTAGAGACAGAGGAAAGGGCAGATTTC +AGTGATAATTAAGAGGAAAGCTGATTGAGTGGATGCAGGAGGAAGGTTGTAATGAAGAGA +AATGAGTCTATTCTGACTCTTGGCTTTCTGGACTATATGGCTGGATAGAGTTTAATTCAA +TTAACCAAAATAAAAAATAGTTTGAAATTTGTCTGAAATTAGCAAGGCTCTCTTGCATGA +GATAGAAATAACTACTTAAGAAAATGGAGTGTCAGCAGCTTAAAAAAAGAACTTTTGCCA +GATTTGAATTAATAGAGACAGAAAGAGAAGCAGTATGGACTTTTAAAGCCAAAGCTAGCA +CTAGGCCTAGCAAAGAGCAGCCACTTGATAAATGTTTACTGAAGTAGCTCAAAGCTGCTA +GCAGTTGACTCAATGTATGGATAAGTAAGGAGACAAGAATTTTAGATACCTAGAATCACA +GTTGGAAAGAAAAAAATAAAGGTTACCTTGGAAGTATACAGAAAATCTAGGTTTAAGTAG +TGTCTAATAATATATTAGAGATGAAAATATTTTTAACACTGAAAACAGAGCAGAGAAAGA +TGTTTCCATTTTCTTAAATCTTGCTGTCATATATTTTGTGTTTTTATAGTTACTAAATTT +TTGTATTAAAAGTTAAGCTTTGTTCACACACAGAAATTAAATACGTAAAATGCATACACA +AACTCTGTACACCTCCCTCTAAAAGGCAAAGCCCAATTCCCTTTCTCTTGAGTATAGGCT +GGGCTTTGTGACTCACTTGGTTATTAACCAACAGAATATGGCAGAAGTGACAATGTGTGA +CTAGGTCATAAAAGGCATCACCACTTCCTCCTTGCTCTCTCTCTCTCTCTCTCTCTCTCT +CTCTCTCTCTCTCTCTCTCTCTCTCATCACTTACTATGGGGGAAGTTGCTATGTTGTGAG +GGCACTCATGCAGCCCATCAATGGTGAGATTCATGTGCCAAGGAACTGAGGCCTCCTGCC +AATAACCAGCACTAACTTGCCAGACATATGAGTGAGCTACCTCAGAAGCAAATCCTCCAG +CCCCAGTCAAGCCTTCAGATGATTACAGCCCTGGCTAATATCTTGACTGAACTTCATGTG +AGACCTTGAGCCAGAATCATCTAGCTAAGGCATTCCTGGATTCCTGCCCCACAGCAATTA +TGTGAGATAATACATGTTTATTGTTTTAAGCCACTAAGTTATGAAGTAATTTGTTACACA +GACATAGAGAACAGTCACACAAAGCTCATTCTCAATTCTGTGCCATTCCTCATGCCATTT +TCCCCAGAGATGTCCTTTCATTATCCATCCCAACACTCCCTCTCTATCCTTCGGTATCTA +ACTGAAGTTTCATGTCTTTGGGAGGCACTTTTTTGTCTATGAAACCATCTCAACTTTCAT +TTCTCTGGCTTCTCCTTTGAAGAAGCCAGATGCTTGACCACATCATTCATTTAGTCATTT +ATTCATACATTCCTCTGTGTTACTGTGCTATACGTTTATATCTTTCCTCCTAAAGATGAA +GATGTCATACAGTTTTTAAAAACTGCATTAAGCACATTATGATTAAGGTACTCAATAAAT +ATTTGCTGATAAAATTAACAAATCTCACACACACTTATAGACACATACCCTGAAAGTGTA +ATTTCAGTAAGTAGCATAAAGTAGTGGTTAACAATATAGAGAAGCTACTTTAGCTCACAT +CTGCATACTTATTAGCTGCTGTCCCTGGGTAAGTTATTTAAAGTATCTCTGTAAGCCTTA +GTTTCTTCAGTGTTTTTAAATGAGAATTCTAACAGTATCTTAGAGTAATAACAAGGTTAA +AGAAAATAATGCATGCAAACCTCTTAACAAAGTACCTAGCATAGAGTATTCAACAAATGT +TAGCTATTATTGTTCTTATAATTAATTACAAATCACAAAATATGTGCTGAAATTCTGAGT +CCCTATGAGTCTCTAGATGTTATCAAGCAGCAATCTAAATTAAGACAAAATTCAAAAGAG +AACTCAGACCTTCTTTTAAAATAGCTTTTAATTCTTAAAAAATCCACTTGTAGGTCACTA +GAACTACAGCCTGAACCAATTGTAGGACTGCAGCCCTGATTCTTTCTCCTCTCTGTCCTA +TTAAGATATTACCTTCAAAGCTTTTGTGGGAACACTTAATTGCTTGCATTCCTTAACATG +CAGCTACCAAAGTAGTTTCCAGATTCACTTTTGACCTTCACAGTCCTGAGAAGGCATATG +AGGCAAACTTCCTAGAGATGTAAATTTAGACAATCTCTGGAATGATAGAGCTATACATAT +GTGAATATGCTACATAAAGCAAATCCATTTTGCATGTCAATTAAAACAGAATCCCATTGA +ACAATCAATCCAATACAACAAATCAATCCAAAAGAATTTTGTTATGGCATGTATCCAAAC +AAGAAAAAACCCCTCCAATGCTATTCAGTCTGAATTACATGAGTTTCATGAACTTGGAAC +ATCTCTAAGATCATACTTTATAATTTGATCATATTTGAACATATTTTAAGGTTTCCTATT +AAAAAGCTAAATATAACGGATGCTCTTCTATCCTAAAAAAGACTGAAGAGATCTGTTAAA +GAAAAACTAGTAGAATGATTTTAAATCACCAACCTATATAAAAACATGCATGCTTTTTTA +ATGTGTTCCATGTCCTCTGCAATAAAATGACCCACTTAATTCAAATTCTTATTTTCTCTT +TTCCCCACCAATACACCTTGAAAACTTTAGTTTTTGAAACATCCAACATACATTCCACTC +TTTATCTGACCCTACATATCACACAATCTGAAATAGAAACAAAGATGGGAAAATTAGCTT +GTTTATTCCACCTTAGTGTCAAACAAAAGTACAAATAAGATTCAGTGCACGTGCCAGTTA +CCTTAGAGCTGCCAATCATGCTTGTTTTGAAACCCTTCAATTTTCAGAGCTGTCAATCCT +GTGTTTTATGATAGAGAGCCAGCATAGAGACAATGCTTTAAAAGACACAATCCTCATTAA +CACATTAGTAAACGGACTTTACTTATAAAACTGGACTTGAAGATTTTACAGAAATGTTTA +CAACTCTCGAAAAATCAAAACTAAAATACAACTTAATGAAATGAAAAGATTTGGAGAATT +TGGCTCTTTGACCAAAGCAACAGCATAGTTTAACCACAGGGATTTTATACACATATATAC +AATATTATATTATAAAAAGAGAATGTTCCTGACTAACACTAATCGCAAGTATTATGACCT +TGAATGGAAATAAGAGAATAAAAGTGATCTACATCCGGGCATTTTAATTTTTGTTTTTAA +AGCAGGCAATAATATCAATAACACACTCCCCTTCTCTACCTCCCCAACACAACCCAACTC +ACTACCCAGTCCATTCATGTCCAAAATGAAACATTATTCAAAATTTTTCTCTCTCACCAA +CCACAACTATTCAGTCACCAAGACCTGTCTCTTCCACCTCCTAAACTGCTAAATGTGTCT +CCTTTCTCCACCCTCAGATTTAATTCATATTCTCATCATTTTTTTCAGCAGCTTCCTTAC +TAACTGCCCTCTCACATCCTTCTTCCGAAATATGCTCCACACCTCTGCCAGAATGATCTC +ACTGAAACACAAAGTTGACCCACGTTCCTTGTTACAATATTTTAATGATTCTTTGCTACT +TTGAAAATAAAATCCCAATTTTTTAGGACAATATGTAAATTCCTTGAAAATCTGGCTCCT +GGTCATCTCCCCACTCTCCCATCACTCCTCCTAAACTTAAGCCAACTAAACCACTTGAAT +TCCCAGAAGAGGCAGCCTCTCTCTCATTTAAAACTTGTTCAAGTGCTGCTCCTTCACCCA +GAAACACTCTCACTTTCGGCACTTAGTATCTCCTACCCATCCTTTGCAACCCAGTTCTAT +TGTTAGTTCCTCTGGGAAGCCTCTGACACAAGCAGATTGAACCATCGATTCCTTCTCCAT +GCCTGTAGAATACAATGAACAGAACTTATATGATGTTATATTTATTGGTTTACTTCTCTA +TCCCCCTGACCAGATCAACTCCCTGGAAGCAGGGATTGTCATTAGTCTGTATGTCACTAG +CCTTAAATACACAGGTAGCACATAATAGATGCTCATTAAAAGTTTGGTGACTCAATGAAA +AATCTTATCATGCCCAGTTCATTTAAAAATAAAATTCATAAAATAAGCAGCTTATTTCTT +GAGATTGATAAAATGTTTTACCAGTGCATTACAAGGCATCCAAACTAATCAATGCTATAA +AGCAATTCTTTGGGCTTAACAAGAGTTTTAAGAAATTTACTCATTTATTTGCAAATTCAC +TATAAGAATTGGTACCATCTCAAGCAGGATTTCGGATTGAATAATTCCACCTTATTTTTG +CTACTGCCCCTACTGGAGGTGTTAAAGTCTCAACCATGATAAATGCTCATGTCCAAAACA +CTCGGCACCTTGATTGGTTCAACAAACACTGTTCTGATATGTGACAATCCCTATCAAGGG +CATCAGTGAACAGGGAGTCGACATAGGCAAAACTCCAACCCAGTTACACTTCACTTATCA +GGAAGTTAGTTATCTGGTGACATCAAGTAGCTACACAGCCCAGTGAGACCTAAACAGAAG +GAGTTTAGGAGCTGTCAGAATACATGTTGAAGTCCATACACTAAAGTACCCACACTTTAC +TCACAGAAGAGGCTGCTAGGTCCTTACTCAAACCCTAGTTGTTCTTATTTTAAGCACAAC +AAATTTGATGACTGATCTCCCAAGTATAGGCATACTGGAAGAGGAAAATTAGGAGGTCTG +AGAAAGCTATAAAAAGCAGACAAGGGCATAACAGCAGTAAAGGAGAGATAACACAAAACT +GCAGAACTGGAGGGTTATATGGTTATGCAGCAATAATTCTGTATATTTTTATTATGATAC +AATATAGAAATTAATGTTTATAATTATGACCCTGGGTCATCAAAAGCAAAAACAAAAAAA +GGTTCAACTATTTTAGGTCTAACAAGGTTCAAAGAAAGTATATAATACATTTTATTAAAA +GAACCAATAAACAATTAAAAATTAAGTATATTAGGTATAAATAGCCAATTTTCTATTATT +TACACAATAAACTTTTTTGAAATACATCATTCCCAAATAACATGAGGCATACTGATATTA +ACCAGGTCCTGTGACTAGAGGTCTTACCACAATTATGATACAGATCCATTACAAAACAAA +GCCTAGACCTGATAGTTATTAGCTTATTGGGGGTTACACTATTCCAACTTACCATACTAT +TTCCTAGTCTGTTCGATCTGAATAACAAAACACCATAAATGAGGGTATCTTATAAACAGC +AGAAACTTCTTTCTCATAGTTCTAGAGGCTGGAAGTCCAGGATCAAGGCACAAGCATATT +TAGTGTCATGAAGACCTGGTTCTGGTTCATAGATTAACTAACTAGCCAGTTCACTAATCC +CACTCACGAGGGCAGAATCCTCATGACCTAAGTACCTCCCAAAAGCCCAGCCTCCTAACT +ACATCACACTGGTGATTATGTTCCAACAAATGAATTCTGCAGGGACACAAACATTCAGAC +CACAGCAACAATGGACACCATAACCAAAGATATAACAGACTACCTATGATTTTTTAACAG +ACCTCCACAGAGCTTCACTGCCACACTGCCTTCAGGGTCCCTGGAATGAAACTGCTTCAT +ATGTAAGACTGTTTTAGGAAGTCTTTATGATGCTTGAGTTACTATATATTGTATGATTTA +GAGTGAAGCACAGCGGGGTGAAAAGAAAATTTGGATATACACAGCCCTAGATTTGAATCC +CTGCTTTGTTAATCCCTAGTTGCATGACTGCAGCACATTATTTATGCTCAGAGACTCATT +TTCTTCATTTGGGAAATGTGGATAATACCTACTATCTATGTTTGTTGTGAAGAATATATA +AGACAATATACATAAAATACCAGTGTAGGTTTTTAAAAAGCTGTTAAGATTATCAGAAGG +AAATCAGATGGAATATAGAAAGGAAACAATCAAGTCTGTGAAATTGTTTGCTGCATTAAT +ATGACAGAAAAAAATGTCTAAAAACAGGTTCCCATGATGGGAAAAGTGCTCTGTATTTTT +AAATTACCATACAAGCCCTCTGACTCACAGAAAGGTTCATGGTAAATTAGGTTAAAGACT +CATAAAAAAAGTATACATGTACACAGCAAAAATATTAACTTAAAGCAGATTAATGCAAAT +ATTCTAATATGGGGCCAAGGCGTTCTCTCTCAGTAGGGGGTCCACTCACTGAAGCTCTGC +TCTTCCTCACATAACAATACCCACACTGCAAGGTCTGTGACTGCCAGGGCCAGTCATGTG +AAAGTAGAACAAGAACAGAAAGACAATTGGAAAGCAATACCTTTCACGTTTTTATAATTT +TTGTTTCAATCTACAGTTTTCTTGCACAATCTAATTCAATAGCAATTTCTTAAAAACAAA +AAACTCTCTCCTTTCTGATTCAAGCAGCAGAGATGGGGGAAAAAAAAAAAACCAAAGTTT +TCTGTTATGGAGTCTTTCTAAAACATTAAAGTTAGCATTCATAAGAACAAAAACCCTTTC +TGTATTCAAATTTTATTAGTTTGTACAATATTCAAGTAAATTTCTTAATATAAACACATT +CTGAAATGAGTACAACTAGGCCGGGCATGGTGGCTTAGCCTGTAATCCCAGCACTTTGGG +AGGCTGAGACGGGCGGATCACTTGACGCCAGGAGTTCAAGACCAGCCTGGCCAACACGGC +AAAACCCTGTCTCCACTAAAAATACAAAAATTAGCTGAGCATGGTGGCACATGCCTGTAA +TCCCAGCTACTCAGGAGGCTGAGGCACAAGAATTGCTTGAACCTGGGAGGCAGAAGTTGC +AATGAGCTGAGATCATGCCACTGCACTCCAGCCTGGGTGACAGAACAAGACTCTGTCTCA +AAAAAAAAAAAAAGAAAGAAAGAAAGAAAGAAACAAGCACAACTGAGCTTTTGCTAAACA +TATACCTCAACTGGAAGAAACCAAAGTGCCTAGGTATAGTACAGGACTACTAATTTCTAA +TGTTCCATGTGGTGTTGGTATCTGTCAGTGGGCTTTACAAAAGAAAAAGATGATGTCAAT +TGATTTGACAAATCAGTTATTAAATGATAACTTCCAAAGAAGTTAATGCCATTCTGAGTC +ATTCTGATTTGTCATATGTGATTTCTGACTTCAAGTCATAAGCTGATTTAAAAGAAAAAT +ATAATAATTATAACTTTTGAGGCTGGTACTATAAGGTCCCATGCATGTCTCAAAATCTCT +AAATATACGTATGTCTATTTTGCAACTCACTCTAAGTAGATCAAATTACTATTGTTCATG +CTTAAGTACTATAGCTTAGATTCTGAATGCTACTATTAAGGTCATGTCTTTCTAAAATTA +GTTTCTTCCTTTCCAAGTGTTTTTCAAACTTTTCTTATTTACAGTAGAAATACTCACCAC +ACACATTAAACAAAATTGTCCCAGAGCTATAATACATAAAACAGATAAATGCAGGGCTGC +TCTGAAAGTAGGGCCCAACTGCCCCTTTATCCCCAATAAGCAATATCTTATGCTTTTCTG +CAAAACTCTAGGGCGTTTTGGTACAAAGACTAAAAACTGCTCCTTTAAACTATAATCAAA +AATGAACATTAAAACAAAAGTTATAGAACTTAAAAGGCTATTATTTAGCTAATTAGAATA +TTCATTAATCAAAATATTTTCTGATCCCTATTAGTTGTTATAAGTCTGAAATGCCAAACT +TACTTATTAAAAGAAACAATAAAAAATTAAAACATTTGGCTAAACTGGATATTTCAATTA +GTTATTTTTCATTGTATTTAATTAATCTTTAAACTGTCCTAAAGTAGCATTATTCAACTA +CACAAAAGTCTGTATGAAGAGAAGAAAATAGTTCTCTAAAAGGATCAAAAAAAAGGGCAG +GCTGATGAATGATGAACAGATTATGTAAATATTTCTCTTATTTATAACAATTTAAAATGT +ACCAAAGCAGGAAGCTCTGCTATTATGGAGATTCAGCCTCCTAGAAGCTGCTCAGTCAGA +GGCCTGACAGTATAACTGCAGAGAACACGTGTCCAGCCCAATAAGCTGTTCTACCTCGTC +ATATAATCTAAACGTACAGGTACAAAAAGGGGAAGACCACAAACAACTGAGCTGGATCTC +ATTACTTCCTTGTTCAGTGATAAAGACAACAGGCAAACATTTGAATTAAGTAGGTTCTTA +CCCACAAATTTTGTTTTAGATATAAGTAGGAGTAATCAGTAACCAAAATAGTAATTATGC +TGACCTGACAATTCTCAATAATATTTTCAAAGCATAAGTGACAGATCCCTATAAGAAACC +TAGAGAAGGGTTTTGGAAAGAACCTAGGCATTTCTACGTGTACAAATGAAGATCTAATAA +TCATTCTGTGAAGAGTATAAACCTTCATTTCATGACAGATTAAAAACTGGAGAACATGAA +ATTTGCTATGTTAAAAAGTTTCTCTCCAAAAAACAATGTATGTCGATAAAGAGCTGGAGT +TGTTATCTACATAGCCGTAAGGGTATGTACATAGGATATGCAGGTAGAGAAAATAAGTAA +TCAAACTACTGATGTTAAACCTTGGCTGAAGATTGGGCACAGTTAGAAATAACATTATCA +GTCTGTAGGACCAAAGAGGAAGCTGAAGAGAGAGAGCTTCAGAGATAGCTGAAGCCTTGA +CTCTTATCTTTTTTTTTTAAAGTCACTTTGATGACATTTCAGACTTACAGAACTAGAACT +AGAAGTCAAAGGCCTTTTTTGACTACTGTTATTTTCCACTCACCAGGCACTCTGTCACCA +TATTATCCATTTTTACTTATGTAATTACCAATATTTTAAATTGATTCATGTACTTGTTTA +CTATCTATGCCTCCTTCCCCCATTTGCATATGCACTTCAAGAGAGCAGAGAACTAGTCTG +TCTGGTTTACCAGTCTTTACAACAGTACCTGGCAAATTGAAGAGGTCTAGTAAGTATTTG +TTGAATGAATGAGTGAATGAATGAATGAATGAACAAATCAACTCCTGTAGCACTTTGGCT +CCTCCCTCTTGATGATCCTCATTCATGAATGTATTTATTTTGTGACTCCTTTGAAGTTTA +AATGGGTATTTCTGGTAAGAGTAACTGGATATTAAGCAGGTGGTTTCATGGAAGCAGGAA +TAGAGAAATTACTACAGATAACTACAGAACAAAGAGATGTAGGCATATAACTCTCCTAAG +TACCTTTAAAAAGACTCTAATATAGTGACTGCTCCAAAGACTAGAGAATTTACTTGCAAA +ATTACTAAGAGCCACCCCGTCTCCCCTCAAAAAGCTTTTATGACTGCTTCACTGGGGGGA +GAACAGACAGAGATGGAGGTTTCAAGAAAACAATTTATATAATAGAATGTGTGCATATGT +GGTATATATTTAGTTTTAAATAAAAAATTAAGATTTAATAAATGTTGTAATAGATGCCAG +TATTTAACCATTTAAAGCTATACTACACATAAAACAAATTCAAATCAGACTATACTACTC +ATTAGAAAACTAATCGCAAATCTGATACTTAAAAATCTGTGACTTAAAGCCAAGCATGGT +GGTACATGTCTGTAAGTCCCTGCTACTCAGGAGGCTGAGGTGGGAGGATTGCTTGAGCCC +AGGAGTTCAAGTCCAGCTGGGGCAATTTAATTCTAGATCTCTAAGGCATTCTGAATATAT +TATGTTCAAGAATATAACATAATCACAAAAGTGATGTTTTAAATTTTTAATTCAATGAGA +AAAAAGAACAGTGCCGACAAAAGAATATCCCCAAAGAAATAAATATCCATGAAAGAGATA +TGATTAACGGAATTCCATCCTCACATATAAAAAAAGTATATGACTAGTATTTGTAATTTA +TAATAAACTTGACTAAGCAGTTGAACATCTGCTGAGAAATATCTTAGCAGAGTTGTCACA +AAATATATCTTTTTATAAAGTCAATACCTGATTCTCCAGTTGCATGTTAGGTCAGCTTGT +AAGAATAAGACAGGCACTGCGATGGACAGCATCCATGGTAGATGATCAATTGTAAGGAGG +GGACTAAGGATTTCTTTGTGTAAAATAAAAGAGCACTTTATTTTATAATTACTATATATT +TTCTACTAATGAAAAAATGATCTGCTACAGCTTCTGCTGATAGTACCTAAGAGCTGAGGA +TACCTCTCTTAAAGGGTAACTTTTGTATCACATATCTTCTTACTTGCCTCCTTCATAAAC +CCTCCTTAAAAGGAATTCTTGAGGGATGTCATCATTAGGTCACCAGGATTTTAATAATAA +CAATGCAATGAAAATAACAATAACAATAGTAGCATTTGTTTACCATATGCCAATCACTTT +TCTAAATTTTTAGACACAATAACTAATTGAATTCCTTCAGTAGCCGTTTACATAACAGAT +ACTGATTACAGTATTAAAATCTGGATTGACAGACACATCCTACTTAGAAATTTCTTTGAG +TCTCCCTACTTTTGAACTAAGCTTGTATGATATTTGATACACCAATTCAAGTCATGCTCA +AGCCATTCCTCTCATGCCAGGGAGCACAGTCTTTCAGTTGACACCTGGTTTATACCACTC +ATCTTGTTAAAACACTGTTCAGCTTCTGGTTATCTAAGGGAGAGGTGTGCTGCAGCCAGC +TAATACCAGCTTGTGAGAAGCACTGTGCACACATCTTCCCAACTCTGCATTCGGTGACAT +CATGTTGGTGACTTGACATTGGCCATGCTGGGAGTATTTCACATTACAGAAATTGGGGCT +TTTTTTTTTAATCAACTAGTTGTTAAATATTTACTCATATATCATTAATCTGAGGAAATG +TGTATTCTGTTAAGTTTGTCAGACCCTATTCAGATTCAGGTAGGACAAGCTTATGTCTCT +AAATTGGGTAAGACCAATTATCAACGGCATCTTTAGATATCCAGCTCTCAGGAGAGAGGC +AACTCGTTCTCATAATTGCTCTCCTAGGTCTACAGTAGACTCTTCGCCTTTCATTTCCAC +AATATGACCAATTTTTATATGCCAAAAACTTCTTAAACACTGTAATTCATCCTATCTAAA +ATACCATTGATTACTAGATTCACTATTGTTTTATATATGATTAAAAAAAAACACTGCCAG +TTAATTTAATATACTGTCAACTGTAACATGCATCCTGATATCAAAAATAGTGAAAAGTAA +AAAATGCACATTAGAAATTGATGGGGAAAAAAAATCACTTCTATCTCGTTTACTATTGTT +CTATTGTTTTCCCATCTCAGAATCTTAGTTCAACCTCTCCTTGACTCTTGATATTCCACT +CCTAGATCTCCCACCTTAGTGCTTTCTCCAGTGCCTATTTATATTCATAAATATCTTTAC +CTACATAAACCACAACAGAATGAACTCTATTTATTAGGAAAAATAATCCTAAAAATAGAT +GCAAAATAATAAGAAAAGAAAGGAGAAGTGGAAAGAGACTATGGAACAGAGAGAAGGGAC +AAAAAAATGGTTCCAGGCAAAATAGCCTAAGCAACATGCATTATTACAAAGTTGGTTTTA +AGTTTATGGTGTGGAATGGCTTATTATCAGGATGAACATTCAAGTCTTCCCAACAACTGC +TCTCACTGCTTTGAGAAGATATGAGTCTGGCCTGACATGACCAACAAGTATTTTTAAAGC +ACTTCAGACTTTACTGCAGCATTATCAAGACAAATAAATATGTTTTCTGTCTTTTCAAAA +AATCACCTTTCATTCAACAATACTTTTGCGCTATCCCAACTTTTATGAATACTCTTAAGG +TACTTGGAAATGATTTTACTTACTCTCCATCCACTTCTGGTCTTCTACATACACAATGAA +ACTTTCCACCAAAATCTATGTACAGATCATTCTCCACAATATGAAAGATCCGTCCAATGA +CCAGTTTATCCTTTGCAGGTCCCATCTGTGTAAGAGGAGAATGTCTCAGCATAGATGCAA +AGGATTCCACATTTTTTGGAGAACCCTAAATATGAAAAGAGATATTTATATACATATAAC +TCAACATGAAGGTATAATAAAGTCTTAAAGAAATTTTCTTAAAGTCAATTGTTGTAGCAA +TAATTTTAAAATATATGTGGAATTTTGCTTTAAAATGCCAGTTATGCTCTTCAACTTCCT +CTTCCATCCTTTCCTTCCTGAAGAGGAGCTAAAGAAAGTAGGCATCAAGGTGGAGCACAG +TGGCTCACGCCTGTTATCCCAGCACTTTGGGAGGCCGAGGCAGGTGGATCACCTGAAGTC +GGGAGTTCTAAGCCTGACCAACATAGAGAAACCCTGTCTCTACTAAAAATACAAAATTAG +GGGTTCCAAGATGGCCGAATAGGAACAGCTCCAGTCTACAGCTCCCAGCGTGAGTGACCC +AGAAGACAGGTGATTTCTGCATTTCCAACTGAGGTACCGGGTTCATTTCACTGGTGCTTG +TCGGACAGCGGGTGCAGGGCAGTGGGTGCAGCCCACCGAGTGTGAGCCGAAGCAGTGCCT +CACCCAGAAAACGCAAGGGGTCAGGGAATTCCCTTTCCTAGCCAAGGGAAGCTGTGACAG +ACGGCACCTGGAAAATCGGGTCACTCCCACCTTAATAGTGCGCTTTTCCAATGGTCTTAG +CCAACGGCACACCAGGAGACTATATCCCATGCCTGGCTTGGAGGGTCCCATGCCCACGGA +GCCTCGCTCATTGCTAGCACAGCAGTCTGAGATCAAACTGCAAGGCAGCAACGAGGCTGG +GGGACGGGCGCCCACCATTGCCAAGGCTTGAGTAGGTAAACAAAGCAGTCAGGAAGCTCC +AACTGGGTGGAGCCCACCAAAGCTCAAGGAGGCCTGCCTGCCTCTGTAGACTCCACCTCT +GGGGGCAGGGCATAGCCGAACAAAAGGCAGGAAAAACCTCTGTAGACGTAAATGTCCCTG +TCTGACAGCTTTGAAGAGAGTAGTGGTTCTCCCAGCACTGAGTTTGAGATCTGAGAACAG +ACAGACTGCCTCCTCAAGTGGGTCCCTGACCCCTGAGTAGCCTAACTGGGAGGCACCCCC +AAGTAGGGGCAGACTGACACCTCACACAGCCGGGTACCCCTCTGAGACGAAGCTTCCAGA +GGAACAATCAGGCAGCAACATTTGCTGTTCATCAGTATTCGCTGTTCCGCAGCCTCTGCT +GCTGATACCCAGGCAAACAGGGTCTGGAGTGGATCTCCAGCAAACTCCAACAGACCTGCA +GCTGAGGGTCCTGACTGTTAGAAAGAAAACTAACAAACAGAAAGGACATCCACACCAAAA +CCCCATCTGTACGTCACCATCATCAAAGACCAAAGGTAGATAAAACAACAAAGATGGGGA +AAAAATAGAGCAGAAAAGCTGAAAATTCTAAAAATCAGAGTGCCTCTCCCCCTCCAAAGG +AATGCAGCTCCTTGCCAGCAATGGAACAAAGCTGGACAGAGAATGACTTTGATGACTTGA +GAGAAGAAGGCTTCAGACGATCAAACTTCTCTAAGCTAAAGAAGGAAGTCAGAACCCATC +GCAAAGAAGCTAAAAACCTTGAAAAAAGATTAGACAAATGGTTAACTAGAATAACCAATG +CAGAGAAGTCCTTAAATGACCTGATGGAGCTGAAAACCACGGCACAAGAACTACGTGACG +AATGCACAAGCTTCAGTAGCTGATTCGATCAACCGGAAGAAAGGGTATCAGTGATTGAAG +ATCAAATTAATGAAAGGAAGTGAGAAGAGAAGTTTAGAGGAAGAAAAGTAAAAAGAAATG +AACAAAGCCTCCAAGAAATATGGGACTATGTGAAAAGACCAAATCTACGTCTGATTGGTG +TACCCAAAAGTGACGGGGAGAATGGAACCAAGTTGGAAAGCACTCTTCAGGATATTATCC +AGGAGAACATCCCCAATCTAGCAAGGCAGGCCAACATTCAAATTCAGGAAATACAGAGAA +CGCCACAAAGATACTCCTCGAGAAGAGCAACTCCAAGACACACAATTATCAGATTCACCA +AAGTTGAAATGAAGGAAAAAATGTTAAGGGCAGCCAGAGAGAAAGGTCAGGTTACCCACA +AAGGGAAGGCCATCAGACTAACAGCGGATCTCTCGGCAGAAACTCTACAAGCCAGAAGAG +AGTGGGGGCCAATATTCAACATTCTTAAAGAAAAGAATTTTCAACACAGAATTTCATATC +CAGCCAAACTAAGCTTCATAAGTGAAGGAGAAATAAAATCCTTTACAGACAAGCAAATGC +TGAGAGATTTTGTCACCACCAGGCCTGCCCTAAAAGAGCTCCTGAAGGAAGCACTAAACA +TGGAAAGGAACAACCGGTACCAGACACTGCAAAAACATGCCAAACTGTGGACCATCGATG +CTAGGAAGAAACTGCATAAACTAATGAGCAAAACAACCAGCTAACATCATAATGACAGGA +TCAAATTCACACATAACAATACTAACCTTAAATGTAAATGGGCTACATGCTCCAATTAAA +AGACACAGACTGGCAAATTGGATAAAGAGTCAAGACCCATCAGTGTGCTGTATTTAGGAG +ACCCATCTCACGTGCAGAGACACACATAGGCTCAAAATAAAGGGATGGAGGAAGATCTAC +CAAGCAAATGGAAAACAAAAAAAGGCAGCGGTTGCAATCCTAGTCTCTGATAAAACAGAC +TTTAAACCAACAAAGATCAAAAGAGACAAAGAAGGCCACTACTTAATGGTAAAGGGATCA +ATTCAACAAGAAGAGCTAACTATCCTAAATATATATGCACCCAATACAGGAGCACCCAGA +TTCATAAAGCAAGTCCTTAGAGACCTACAAAGAGACTTAGACTCCCACATAATAATAATG +GGAGACTTTAACACCCCACTGTCAACATTAGACAGATCAATAAGACAGAAAGTTAACAAG +GATATCCAGGAATTGAACTCAGCTCCACACCAAGTGGATCTAACAGACATCTACAGAACT +CCCCAACCAAAATCAACAGAATATTCATTCTTCTCAGCACCACATCACACTTATTCCAAA +ATTGACCACGTAGTTGGAAGTAAAGCACTCCTCAGCAAATGTAAAAAAGAAATGATAACA +AACTGTCTCAGACCACAGTGCAATCAAACTAGAACTCAGGATTAAGAAACTCACTCAAAA +CCGCTCAACTACATGGAAACTGAACAACCTGCTCCTGAATGACTACTGGGTACATAACAA +AATGAACGCAGAAATAACTAAGATCAGAGCAGAACTGAAGGAGACAGAGACACAAAAAAA +CCTTCAAATAATCAATGAATCCAGGAGCTGGTTTTTTGAAAGGATCAACAAAATTGATAG +ACCGCTAGCAAGGCTAATAAAGAAGAAAAGAGAGAAGAATCACATAGACGCAATAAAAAA +TGATAAAGGGGATATCACCACCGATCCCACAGAAATACAAACTAACATCAGAGAATACTA +TAAACACCTCTACGCAAATAAACTAGAAAATCTAGAAGAAATGGATAAATTCCTCGACAC +ATACACCCTCCCAAGACTAAACCAGGAAGAAGTTGAATCCCTGAATAGACCAATAACAGG +CTCTGAAATTGAGGCAATAATTAATAGCCTACCAACCAAAAAAAGTCCAGGACCAGACGG +ATTCACAGCTGAATTCTACCAGAGGTACAAGGAGGAGCTGGTACCATTCCTTCTGAAACT +ATTTCAATCAATAGAAAAAGAGGGAACCCTCCCTAACTCATTTTATGAGGCCAGTATCAT +CCTGATACCAAAGCCTGGCAGAGACACAACCAAAAAAGAGAATTTTAGACCAATATCCTT +GATGAACATCGATGCAAAAATCCTCAATAAAATACTGGCAAACCGAATCCAGCAGCACAT +CAAAAAGCTTATCCACCATGATCAAGTAGGCTTCATTCCTGGGATGCAAGGCTGGTTCAA +CATATGCAAATCAATAAATGTAATCCAGCACATAAACAGAACCAAAGACAAAAACCACTT +GATTATCTCAATAGATGCAGAAAAGGCCTTTGACAAAATTCAACAACCCTTCATGCTAAA +AACTCTCAAGCAATTAGGTATTGATGGCACGTATCTCAAAATAATAAGAGCTATCTATGA +AAAACCCACAGCCGATATCATACTGAATGGGCAAAAACTGGAAGCATTCCCTTTAAAAAC +TGGTGCAAGAAAGGGATGCCCTCTCTCACCACTCTTATTCAACACAGTGTTGGAAGTTCT +AGCCAGGAAAATCAGGCAGGAGAAAGAAATAAAGGGTATTCAATTAGGAAAAGAGGAAGT +CAAACTGTCCCTGTTTGCAGATGACATGATTGTATATTTAGAAAACCCCATCATCTCAGC +CCAAAATCTCCTTAAGCTGATAAGAAACTTCAGCAAAGTCTCAGGATACAAAATCAATGT +GCAAAAATCACAAGCATTCTTATACACCAATAACAGACAAACAGAGAGCCAAATCATGAG +TGAACTCCCATTCACAATTGCTTCAAAGAGAATAAAATACCTAGGAATCCAACTTACAAG +GGACGTGAAGGACCTCTTCAAGGAGAACTACAAACCACTGCTCAACGAAATAAAAGAGGA +TACAAACAAATGGAAGAACATTCCATGCTCATGAATAGGAAGAATCAATATCATGAAAAT +GGCCATACTGCCCAAGGTAATTTATAGATTCAATGCCATCCCCATCAAGCTACCAATGAC +TTTCTTCACAGAATTGGAAAAAACTACTTTCAAGTTCATATGGAACCAAAAAAGAGCCCG +CATTGCCAAGTCAATCCTAAGCCAAAAGAACAAAGCTAGAGGCATCAAGCTACCTGACTT +CAAACTACGCTACAAGGCTACAGTAACCAAAATAGCATGATACTGGTACCAAAACAGAGA +TATACACCAATGGAACAGAATGGAGCCCTCAGAAATAAAGCCGTGTATCTACAACTATCT +GATCTTTGACAAACCTGACAAAAACAAGAAATGGGGAAAGGATTCCCTATTTAATAAATG +GTGCTGGGAAAACTGGCTAGCCATATGTAGAAAGCTGAAAGTGGATCCCTTTCTTACACC +TTATACAAAAATTAATTCAAGATGGATTAAAGACTTAAATGTTAGACCTAAAACCATAAA +AACCCTAGAAGAAAACCTAGGCAATACCATACAGGACAAAGGCATGGGCAAGGACTTCAT +GTCTAAAACACCAAAAGCAATGGCAACAAAAGCCAAAATTGACAAATGGGATCTAATTAA +ACTAAAGAGCTTCTGCACAGCCAAAGAAACTACCATCGGAGTGAACAGGCAACCTACAGA +ATGGGAGAACATTTCTGCAATCTACCCATCTGACAAAGAGCTAATATCCAGAATCTACAA +AGAACTCAAACAAATTTACAAGAAAAAATCAAACAACCCCATCAAAAAGTGGGTGAAGGA +TATGAACAGACACTTCTCAAAAGAAGACATTTATGCAACCAAAAGACACATGAAAAAATG +TTCACCATCACTGGCCATCAGAGAAATGCAAATCAAAACCACAATGGGATAACCATCTCA +CACCAGTTAGAATGGTGATCATTAAAAAGTCAGGAAACAACAGGTACTGGAGAGGATGTG +GAGAAATAGGAACACTTTTACACTGTTGGTGGGACTGTAAACTAGTTCAACCATTGTGGA +AGACAGTGTGGCAATTCCTCAAGGATCTAGAACTAGAAATACCATTTGACCCAGCCATCC +CATTACTGGGTATATACCCAAAGGATTATAAATCATGCTGCTATAAACACACATGCACAC +ATATGTTTACTGTGGCACTATTCACAATAGCAAAGACTTGGAACCAACCCAAATGTCCAT +CAGTGATAGACTGGATTAAGAAAATGTGGCACATATACACCATGGAATACTATGCAGCCA +TAAAAAAGGATGAGTTCATGTCCTTTGTAGGGACACGGATGAAGCTGGAAACCATCATTC +TCAGCAAACTATTGCAAGGACAAAAAAACCAAACACCTCATGTTCTTACTCATAGGTGGG +AATTGAACAGCGAAAACACCTGGACACAGGAAAGGGAACATCACACAGCAGGGCTTGCTG +TGGGGTGGGGGCAGAGGGGAGGGATAGCATTAGGAGAAATGCCTAATGTAAATGACGAGT +TAATGGGTGCAGCACACCAACATGGCACATGTATACATATGTAACAAACCTGCACATTGT +GCACATGTACCCTAGAATCTAAAGTATAATAAAAAATAAATAAATAAATAAATAAAAATA +AAAATACAAAATTAGCCAGGCATCATGGTGCATGCCTATAATCCCAGCTACTCATGAGGC +CGAGGAAGGAGAATCACTTGAACTCAGGAGGCAGAGGTTACGGTGAGCCGAGATCACGCC +ATTTCACTCCAGCCTGGGCAACAAGAGCCAAACTGTCTCAAAAAAGAAAAAAAAAAGAAA +GAAATTAGGCATCTATACTTGGTGGAGGATGACAGAGATGTGATAGTCCAGGGTGAGGTC +TCGAGAGCCCAGGCAGGGTAGGGAGAGTAGAAGAGTGCCTGTATATCAAGTCTCTGAGAA +TGGGGTGGGGGGTGGTTAGTGGTCAGAGTATGAGCACGTGAGGAGGGCATCCAAGAAGCA +ATTGACTTTATTCCTAGCACTGACCATCTGTAAAAAAATGCCTTCTAAATCAAGTTTAGT +GAAAGTCACTATTCTTTTAATACAAATGTAAATATACATTAAGATAAAAACAATTAAGAG +CCTTTCATCACAATGATCAGTCTGAACATGAGTTCCTGATACATAATTCTTTTTAAACAA +CTTGAATTTGTTATACTTTTCTTTCTCCTAAAGTAAATTCCAAAAGAAAAACAGCTTGTT +TTGTGCTATTCACTTTCCGGGAATCTTTTTACATATTGAATTCACTTGAGGTATGACTAA +TTATTCTTTTTTTCTTACAAAAATTTTTTCCAAACACATTTTTTCCAAATCCGTGAACAC +AGATTTGTGCCTTCTACTCATTTTTGTGTATGGAGTGGTGTGTGCAATTTGGTACAAACT +AAAGGAAGTGCTAAGTTTCTATCTGTGAGAGCAAATCATGGAAGGACATTAACAATTTGA +TCTGACGACCTAAATGCTGTATTTGGAATGAGTTTTACATTTGTTATTCGGGGAGAACTA +CTAAAAGTTCAATAGTAAAGCACATTTACTTTTAAAGCTACACAACTATATTTGTGACTT +AAGTTTAATGCATGTACTACTTGAAAGATTATAAACTCAAATGCCAGGCCAGGTGAGGGC +TTGATAATCAGGATATGTGCCCAAGTTTAAAAGGTGTAGACACTACTCAGCTCCAGCTGC +AGCTGCAATTCAAGTCCCCATGTTTTAATTTTTAATGTTTTAATTTTCCAAGAAAAGCCA +GAAATCCACATATTAATGTAAATTTTCCAATTTTTAAATACTTATATGCAGGGGGATAAA +GTTTTCCATTTTACAAACCCGGCAAAACACATCCAGGTGTTGAATTTGGCCCACGAACCA +CAAGTTTATGACCTCTGCTTCAGGAAAAAGAAAGTCACGACATTTGGCTTATGCCAAGTC +CCTCAGGTGCTAGAGGGAGGGTATGATGATGAATTTACTTGGTGAACTGAAACACACAGG +GAAAAAATCCTTAGCACAAAAGGGTCAATCTAAACTAAAGACAAGTCAGTAGGCCTAGAG +GCCAACTAGAGCTGAAAAGGTAACCAGGAATGTATGCCATGAGCAATCATACTAGTTTTA +TAAATCCACAAAATACAACATTAAAGGTCCTTAAACAAGCACTTTGAAAATAGTTCTTTC +TTGCAGAGCCAGAGATAAAACAAATCCTACAGAGGTAACACAGACACAGCTGACTTGCCC +TTTAGAGGTAGTGTAAAAGAGTAATTCTAAGTAAGCCATTCTTTTTTTTTTATTTTTTTA +TTTTTATTTTTTTTTGTAAGCCATTCTTGACAAGAGCAGCTACATAATCCTTTGCTGGGA +GCCATTATTCCATCCATAGTAGCTGCCACTAAAGCAGATGAGAATAGCAGTGCTCAAGAG +AAGAGCAAACAGTATCAACTTGGGGGTCTCTGCTTGTAACCAGGGCAGGTCCTGCCCACT +TTCCCTATGATCTGCTTTCCCATTACTCCACTTTTATGGTTGATATCTACCAGAGTTCCT +CTGTTCTTTTTCTTCTTTTTTCGCTTTGGCTATTTTTTTTTTTCAATTGGCTGACTTTCA +ATTGAAGCCATAGTCCAATTAAAACTAAATGACAGGGGCTAGGCATTGTGGCTCACGCCT +GTGATCCCAGCACTATGGGAGGCCAAGGTGGGTGGATCACTTGAAGTCAGCAGTTCAAGA +CCAGCCTGGCCAACACGGTGAAACCCTGTCTCTACTAAAATACAAAAATTAGTCGGGCAT +GGTGGCATGTGCCTGTAATCCCAGCTACTCAGGAAGCTGAGGCAGGAGAATCACTTGAAC +CCAGGAGGCGGAGGTTGCAGTGAGCCGAGATGGCACAACTGCACTCTAGCCTGGGCGACA +GAGTGAGACTCTCAAAAAAAAACAACAAAAAACAAAAACAAAAAACAAAACAAAACAAAA +AACCAGATGACACTAAGATACAGTAGTAGCAGATCCAGTAGTTAAACTTTTACTGGAGAT +AATTCAGCCATCACTAGGACCTGTTCCTAAAATAACACAATGTCCTTTTTCAATTGTGAA +GAGATGTTTGAGCTAAGATTAGTATAATAGTAAGTGGTATTTTCCCCTTGGTTTTAGAAA +ATTATTGAGTGCTCTCAACTGTTTAAAAAGATTCTCTTGAGATTTTTAGTAAGTCTGCAG +TTAAATATTTATTACATTATAAACTTTATAAAGTTATAGTTACTTTTTATAGGTAACTTT +AAAATCAAGTGGAAGTAGAACATTTCTCCTCCATTTTTTGCCTCTATTATATTTTGCAAG +GAAGTCAGTGTGTTTTTGGCGAGTGAAATAATTTTACCACAAGCATAAGAACCCTGGATT +AACACCTGAATTTGCTTTTAAATTGTAGCTTATTATTTCATTTGATTTTTGATATTGCAT +CATTGATTTTGGGAAGCTACATCAAACAATCAGACAAACCCTTGCTTCAAAAATCATAGT +CTAGAACCATCTCTGAATCCTAGGGCTTATGCCAAAATGTACTCATTTACTTGTCAAATG +ACTCCTAAAAACAGTAAATGTAGCAACTCCCACAATCCATGTTCACTACAGGGAGTCCTG +TTTATAAAGTCTCTAAACTAACATTGATAGCTCCTCTCATGCTGATATAGACTGCAGAGA +CTGGAAGCATACTGTCACCGCTGGATATGTATCATAGAGCTCAGTGCCTAACCCTGGAAA +ATGTTACAATAAAGCTCACTAACTGAGCTGTCACAGGTACTAACTTGGAGTTGACTATTT +CCTTTAACAGTTGGTCATAGAGATCAGATCTCCTGCTATTCTGCTGTACTATTTTCTCCT +TTGAAGCCTGAAAGTTGACAGGACCGTCAAGGTAGAAAGGAGTAAGGTAAAGGAATTACA +GACATATGGAACAGTATCACTTTCATTTATTCAATCATGCATTCATTCATTCATCAAACA +TGTGTTGTCTTTTTAATATATATTAAGCATATATATACCTATCATGCATATGAGGACCAT +TTAATATACAGCTTGGAAACAGGGGCAACTAGTGCTAAAAGAATATGAGACATCAACTAA +TCCAACTACCTCAAGTTTTACATGAGTACCATACATGCTATTCAAAGTTACATGGGATAC +TGAACAGTGGTTCTTAAATAAAACTTGCTGCAGAAGATAGAAAATAGATAAAAACATCAT +AGCAAACTTAAAAGAAAACAGTACAGAAGAATAACAAATACGAAACCTGACTTCTATGAC +CAACTCAGCCAATAAACAGCGAAAAAAAAACCCTGAATAAGTCATTTAACTTCTCTAGAT +CTGTTTTCTCATTTGTAAATTAAAGGATTGGATAACTATAAATTTTCTTCCAATTCTATA +AGGTAGTAGGAATTCTTAAATATTCTAAAATATAAAAAGGATTTTATAAAACAATACAAA +TTAGAAATGGGAGACAACATCCTACCCAGTTACCTCTTTTAATGTAGACAATAAAAACAG +CTGGGTGCAGTGGCTCACCCTGTAATCCCAGCACTTTGGGAGGCTGAGGTAGGTGGATCA +CCTGAGGTCCGGAATTCGAGAACAGCCTGACCAACATGGGGAAACCCTGTCTCTACTAAA +AATACAAAATTAGCCGGGTGAGGTGGTGCATGCCTGTAATCCTAGCTACTCAGGAGGCTG +AGGCAGGAGAATCACTTGAACCCAGGAGGTGGAGGTTACGGTGAGCTGAGACTGCGCCAT +TGCACTCCAGCCTGGGCAAAAAGAGCAAGACTCCATCTCAAAAAAAAAAAAAAAAAAAGA +AAAGAAAAAAGAAAAAAAACAATAACAATAAAAGTAATGAAATGGTATATATACTTTAAC +TACTTCATACTGGTTAGCAAGAAAAAAATTTCAACATGCATCTCCAAAAATGACCCACTT +CTATTAACCGTGCTATAATAACTTTTGTTTCTTTAACACTAACCAATAAATGTTACGCTC +GCAACAGAGTTCTTTTATTGAAATAAACGTATTGGTGGCTCAAGGTGATAAGGTACTTAC +ATTTATCTCTCTCCCTCCTGAAATCCCATTAAATGATGGTAAAATAATAAATTAAAAAAT +TGTAAAAATTATAAACTCTCAATATTGAAGAGAACAGATGGAGAACAAAAGTATACAAAC +ATACTTTCTAGTGGACAGAAAGCATGTGGAAGAGTGATAATTAATGAAGCAGAGTGAAAT +TCAAGAAGAAGAAGCTGTGAAAAAAAGAAAGCTATTCTATCCTGAAGTATTCCATAAAGG +TATGGAGCTCAGTCATGCCAGGCTGCAGTGAGAAGACAAGCTGAAAACAAGGAGAATAGC +TAAAAACAACAGAGGCAGGGCAGTCAATATTCTGTCAAGCACAAAATTCCTCAAGTGCAT +AATATCTGGTAATAGGCATGTATTATCCTGTCAAAAATAAATATATTTTTTCTCTTCCCT +TAAAAAAATCAAACAAATTGTACAGAGGAGAGCCAAGTTTGGGATGGTTTGTTATGCAGC +AGTAACTTATACTGTTTCTATAACCTATAGAAGCAGCAAAGAAAAGACTCCAAATGACAG +CTGTGCAGCAAGCATATGAACAATTTGTGATGATTCAAATACGAGGGCTCCCAAAGGAAG +GCTGGGAAGTCTGGCCACATGGCTTGAACCTTGGCTCTACCGCTTACCAGCTCTGGGGAC +AGGTCTGTGCACTTAGAATCTCTGTGCTGCTGTTTACTCATCTTATAAAATGGTGTTTGT +AATTATATCTATCTATTTTACAAGATTGTTGTAAGGAATAAATGTGTGGCCATATGTAAA +GCACTCAAATAGTGTCTGAAGGTAAACAGACCCTGTCAAAAACTTTAGCTTCTTTAAAAA +TTAATTTCTTATAGACTCAGTCACCACCATCAAGTTTTATTGACTAATCTAGTATTTGTC +AACCAAGATGATTTCCCCCCTGCCACCCCCACTCCAGGGGACATTTGGCAATGTCTGGAG +ATGTGTTTGATTGTCATGACTGAAAAATCAACAACTCTTCTTAGATGCATCTGAGAGGTG +GGGGTCACAGGGAAAACTGCTGTTCTCAAATGTGGAGAGACAAGTGAATGCAGAGAACTA +CTGAAAAGAAGCCTCCAAGAAGAAACCTCTGTGGGAACCAGTGCCGAGGTAGGGAAACCC +GAGCTGTAACTGGTGAATTGGTGGATGCTCAGTGGGACAAGTCTGAAAGTTAAAAACTCC +AGAGAGACTCAGTTATTGGGGACTCTCACACTTTTGTGAGTTTTAACTCCAGGAGCTCAA +CCTGGTCCTTACAGTGAATATAGGAGAAAAATCCCCTTGTACTTCAGACGGCAAGTTCTG +TGGGGAATAGAACTATTTTGAAATACATCAGAGCACTCTCTCTTATTCAACAATTCATTT +ATCAAACAGGTGTTGTCTTTTTAATATACATTAAGCACATATATAAAACTATCATGCATA +TGACATGTGTCCTCAAGGAAACTCTTCAACCAAAGCCTAAACACTTGTCAGAGCCTAAGT +GTCCTGGAGGAAGGGAAATAACCAATTCTAGCTGGCACTAGTCATTCTGTCCTACCAAAA +GAGAGGGAAACACTGAGAAGCAAATGTGCAGTTCATAGTCCAGAGGCACAGGCTCACTAG +AAGACTGAGACCCACTCATAAGACTATAGAACACTTTCCCTCCCCACACACCCTATCACC +ACATTACTAAAGGCCGATTGACAGCCATTCCTTTTACCCAATACATCATGCCCAGCTATC +AAAAAGAAATTACAAGATAGACAAAAAAGCAAAAAACACAGTTTGAAGAGACAGAGCAAG +GATCAGAACCAGATTCAGACACAGCAAGGATACTGAAATTATCAGTCCAGGCATCTAATA +CAACTATGATTAAGACACTAAGGGCTCTAACGGAAGAAATAAGATGTAAGAACAGATAAG +CAATGTACGCAGAAAGATGGAAATTTTAAATAAGAATCAAAAAGAAATGCTAGAGATCGA +AAGCCCTGTAACAGAAATGAAGAATGCCTTTGATGGGCTTACAGGTAGATGACACAGCTG +AGGAAAAAAAAAAACTGTGACTCTGAAGATACCTCAATAAAAACTGCCAAAACTGAAAAG +CAAAGAGAAAAAAGATTGAGGGAAAAATTGAACAGAATATTCAAGAACTTTGGGACAACT +ACAAAAGGTGTAAACTAATGGGAATTCTAGAAGGAGAAGAAAGACAAATACAGCAGAAAT +ATTTGAAACAATAATGACTAAGACTTTCCTTCAAATTAATATCAGACACCAAACCACAGA +TCCAGGAAGCTCAGAGGACATCAACCAGAATAAACACCAAAAACACTACATCTAGGCATA +TAGTATCATTTTCAAACTACAGAAAAATCAAAGATGAAGAAAAAATTCTAAAAGAAGCTT +GGGGGGAAAACAGCTTTCCTACAGAGGAGAAAAGATAAAAATTATATCCAGCTTCTCCTC +ATAAATCATGCAATCAAGAAAACAGTGGAGTGAGATATCTAAAGTGTTAAGAGGAAACAA +AAAAAAAAAATACTAACCTAGAATTCTGTACCCTGACAAGTTATCCTTCAAAAATGAAGG +AGAATTAAAGACTTTCTCAGACAAATAAAAATTGAGGGAATTTGTTGCAAGTAGACCTGC +CTTGCAAGAAATGTTTAAAGAAATTCTTTAGAAAGAAGAAAATTATAAAAGTCAAAAACT +CAGATCTACATTACATAAAGAAAGGCAGAACACAGAGAAGGAATATGTGAAGGTAAAATT +AAAACTTTTAAGTTTTTAATTAGTAATTGATCTAACAATTAACAGTTTGTTCATGTTAAA +CAATTTGCTAATAATAAAAGGGTTAATTATCTGAAGAAGTCGGAATAATCCTTAATGTGT +ACATGCCTAAAAATAGTCAAAAACCATGAGGCAAAAACTGACAAAACTGCAAGGAAAAAT +AGATGAATCATTACAGTTGGAGACTTTAATGTCCCTCTATCAGAAAAGGACAGATCCAGC +AGGGAGAAAATCACTCAGGATATAGCTGAACTCAACAACATCATAAATCAACTGGATATG +ATGGACATCTGTAGACAATTTCATCCAGCAACAGCAGAATATATATTCTTCTCATGCCAC +ATGAAACAGTCACCAAAACAGACCACATTCTGGACCATAAAACACACCTTAACAAATTTA +AAGGAATAGAAATCATGCAATGTCTGCTTTCAGACCACACTAGAATTTAACTAGAAATCA +GGAATAGAAAGATAGCTCAAAAATCCCAAAATTCTTAGAGTAAACAAATACACGTCTAAA +TAACATGAGTCAAACAAATCTCAAGAGAAATTTAAAAATACTTTGAACTAAATGAAAATG +AAAACACAACTTATCTAAAATAAAAATTAGCACAGAAAGCAATGAAACTGAAAACAGGAA +ATCAATAGAATCAACGAAAGCAAAAGTTGGTTATTTGAGGTAAGCTTCTAGCCAGACTAA +GAAAAACAAAAAGAGAGGACACAAATTACTAATAATAGAAATGAAAGAGAGGACATCACT +ACATATCCCATGAACATTAAAGAAATACTATAAACAACTCTATACCCACAGATTTGATAA +CCTAAATTAAATGGATTAATTCCTTGAAAGACAAAGTCTGCCAAAATTCAAGTAAGAAGA +ACAGATAATCTGAATAGGCCTATGTCTATTAAAGACATTAAATCAGTAATTAATATACTT +CCAAAACAGAAAGCCCCAGGTCCATATGGGTTCACTGGTGAGTTCTACCAAACATTTAAA +GAAGAAATCAAACCAATTCTCTACAATCTCTTTCAGAAGATAGGAGTGGAACTTATCCTA +TGAGGACAGTAATATCTTAATATCAAAACCACACAAAGACATTACAAGAAAAGAAAACTA +CAGACCAATATTTCTCATGCATGTAGATGCAAAAATCCTCAACAGAATATTAGCAAATCA +AATCCAACAACATATAAAAATTATATACCACAACTGAGACTTACGACAGGTTTAACATTC +AAAAATCAAAATGTAGACAAAGCATTAATAACCAGGATATATAAGGAGTTCAAACAACTC +TATAGGAAAAAAATTCTAATAATCCAACTTTAAAATAGGCAAATAATCTCACGCCTATAA +TCCCTGCACTTTGGGAGGCCGAGGCGGGCGGATCACAAGGTCAGGATATCAAGACTATCC +TGGTTAACATGGTGAAACCCCATCTCTACTAACAATACAAAAACAAAACTAGCAGGGCAT +GGTGGCAGGCGCCTGTAGTCCCAGCTACTGGGGAGGCTGAGGCGGGAGAATGGCATGAAC +CCGGAAGGAGGCAGAGCTCGCAGTGAGCCGAGATCGTGCCACTGCAATCCAGCCTGGGAG +ACAGAGCAATACTCTGTCTCAAAAAAAAAAAAAAAAAAAAAAGGCAAATAATCTGAATGG +ACCTTTCTCGAAAGAAGACATACAAATGGCAAACAGGCTTATGAAAAAGTGCTCAACATC +ATTATCATCAGAGAAATGCAAATCAAACCTACAATGAGATATCATCTCACCCCAGTTAAA +ATGGCTTTTATCCAAAAGACCAGCAGTAATACATGCTGATGAGGATGTGGAGAAAAGGGA +ACCATCATATACTGTTAGCGGGAACATAAATTAGTACAACCACTCTGAAAAACAGTTTGA +AGTTCCACAAAAAACAAATAACCAAAACTAAAAATAGAGCCACCATATGATCCAGCAATC +CCACTGCTGGTTTTATACCCCAAAGAAAGGAAATCAGTATACTGAAGAGACATTTCCCAT +GTTTGCTGTAGCTCTGTTCACAATAGCCAAAATTTGAAAGCAACCTAAGTGCCCATCAAC +AGATGAATGGATAAAGAAAATGTGGTACATATACACAATGCAGTACTACTATTCAGTCAT +AAAAAAGAATGAGATCCTGTCACTTGCAACAACATGGATAGAACCAGAGGTCATTACGTT +ACGTGAAATAAGCCAGGCACAGAAAGACAAACTTTACATGTTATTATCTGTGGGAGTTAA +AAATTTAAACAATTGAACTCATGGAGACAGAGTAGAAGGATGGTTACCCAGACGCTGGGA +AGGGTATTGGGGGTTTGTACCTATTAACCATCCCCACTCCCCTATATGTGATATAGTATA +CTTATAGTATATAAGGGGGTGGGGATGGTTAATGGGTACAAAGAGTAGTTAGAAAGAATG +AGTAAGACCTAGTGTTTGAGAGCACAACAGGGTGATAAGCAATAATTATTTAACTGTATA +TTTAAAAATAACTAAAAGAGTTTAATTTGATTGTTAACACAAAGAGTAAATGCTTGAAGG +AATGGATACTCTATTTACTATGATGTGATTATTACATGTTATATGCCTGTATCAAAGTAT +CTCGTGTGCCCCCTAAGCATATACACCTACTATGTACCCACAAAAATTAAAAATAGAAAA +AAAATGTAATCCATCACATCAATTGGCTAAAGAAGAAAAATCACATGGTCGTATTTCATT +TCGTCAAATGGAAAAGCATTTGACAAAACCCAATACCCATTCATAATAGTAACTCTCAGA +AAACTAGAGAAAGCTTCAACTTCCTAAAGAATATCTACAAAAAACCTACATATGTAATGG +TAAGTAACTTGAAACTTTTCCTACTAAGCACAGGAAGAAGGCAAGGATGTCCCCTCTCAT +CACTGCTTTTCAACATTGTACTAGAAGTCCTAGCTAATGCAATAAGACAAAAAGAAAAAA +TAAAAGTATACAGATTGGGAAGGAAGAAATAAAACTGTGTATGATCATGGATGGCATGAT +GACCTATGTAGAAAATCAAAAAGAATCAACAAGAAAAAAACCTCCTGGAATAAGTAATTA +CAGCAACATTACACAATATAAGGTTAATATACAAAAAACTATGTGGCCAAAGTATTGGTA +GTCATTAATGTGTAAACCAAGAGTATGAGACAGGTCTAAATCAATTTGGAAAGTTTATTT +TGCCAAGGTTAAGGACACGCCCATGACACAGCCTAAGGAGGTCCTGAGACACGTGCCCAA +GGAAGTCAGGGTACAGCTTGGTTTTATACAATTTAGGGAGACATGAGACATCAATCAATA +CGTGTAAGATGTACATTGGTTACACTGGTTCAGTCCAGAAAGGCAGGAGAACTAGAAGCA +GGTTGCGAGGGTGGCTTCCAGGTCATAGGTAGATTTAAAGATTTTCTGATTGGCAATTGG +TTGAAAGGGTTATTATCAATAGAAAGGAATGTCTGCGTGACCATAAGGCATTGTGGAGAG +TATGGTTTTATCATGCAGATGAAGCGTCCAGGTAGCAGGCTTCAGAGAAAACAGATTGTA +AATGTTTCTTACTAGACTTAAAGAGTCATTTCTATCACTAATTCTGAAAGGAGGGAGGTA +TAATGAGGCACGTCTGGCTCCCCCTTCCCATCACGGCCTGCACTAGTTTTTCAGGTTAAC +TTTGGAACGCCCTTGGCTGACAGGAGGGGTCCATTCAGATGGTTGAGGGGGCTTTAGAAT +TTTATTTTTGGTTTACAAATGTAAATGCTGGTCAATGAAAATGGTAAGTATGAAGAAAAG +AGAAAAGCTGTGAGCCAGATGCTGACGAAAAATGGAAAGAATTGAAAAGATTTTTATCAA +GGAGCCTTTTTAAAGTATTTCTGATAGAACAGTAGTCTGAAATGGTACTGAGAAACGAGA +ACGAAGATGAGTCATTTTTTCCTCCTAGCCTTGAGACCCGTTGCAATCTATACTAGGGAA +GACCAGAAGGGAAGCAGTGTTATCAAGGGAAACCAAGAAAGCAAGCAAGAAATACTTGTA +GAGAAGGTTAAAGGGGAGATTGTTCGTAAAAAGACATAGGAAATTTGTGGCCAACGAACA +CACATTTACAGAGCAGGCCTGAAGGAAAAAGGTCAGGTTGTAACAAAGAATAGTGATCTC +TATCATAACCCATAGGACAGAAGAAGAAAACACTGGAATTTCTATTTGTTTTTTTTAACT +TCACCTTCAAAATGTTTTTATGTGTAAATGCTTTAAAATGTATATAACAAAAGAAACTAC +AGTACGAATATATATATTCGCACACACACACTTTTTTTTTTTTTTTGAGACTGGGTCTCT +TTCTGGCGCTAGGCTGGAGTGCAGTGGCACAATCTCGACTCACTGCAACCTCCGCCTCCC +ATGTTCAAGCAATTCTCCCGCCTTAGCCTCCCGAGTAGCTGGGACTACAGGCATGAGCCA +CCATGCCCGGCTAATTTTTGTATTTTTAGTAAAGACAGGGTTTCACCATGTTGGTCAGGA +TGGTCTTGATCTCTTGACCTCATGTTCCGCCCACCTTGGTCTCCCAAAGCGCTGGGATTA +CAGGTGTGAGCCACTGCGCCCAGCCACAAATGTATTTTTTAAGTAAATACTGGAACATCT +GCTCAAAAATTTATTAATGAAGGGACATGATCAAAAAAGTTTAGAAATCTCTGTAATAGT +GGTATATCGTGGGAGCAGGAGAAACATTATGCTAGATAGGGAAAAACAGTTACAAAAGGA +GACTGGACAGTCAGTCTCTCTCTCATTTTATGAGCAGAGCTGTAAGCCAGATGCTGACAG +ATGCATAGACTGGGACCAAGGGATGCTTTTAAGGTTTCTAGTAAGACAGAAGTTGTCTGA +CTAAAGGCTAAGGTATGCAGGTAGGCATGTGGAACTTTACTTCTAACTATTCTTGGATTT +TTCTGGTATTCTACACTGCATTGCTTCTAACAACAAAAAATTACCTTACAGGAAATAATG +TGGGATAACTGTCACATGTTTATGGAATTCAATGGTCTTATCAGTGCTGGGCCCGAGAGA +CCAGTGAAATGCTCCCTTTAAAAAAAATTAACTTTCTATTTAAAAATCATTGTAGATTCA +CATGCAATTGTAACCAAGAATACATAGAGAGCCCCTGCACCCTTACCCAGGGCTCCCAAT +GGTAACATTTTAGAAGACTATAGTATGATATCACAACTAGGAAATTGACATTGACACAAT +CCACCAATATTCAGATTTCACCAGTTATACACGTAATCATCAATGCAATTTTATTACATG +TAAAGGTTCTGTACTGGCCATCACAGTCAAAATGCAGAACAAGTCCATTACCACAAGGAT +TCCTTGTGCTGTCCTTTTGTAACTCCACATATCCCTTTTACCTCCCTCCTTCCTAACTCC +TAGTAAGCACTGACCTGTTCTCCATCTCTATAATTCTGCCATTTCAAAAATGTTGTATAA +ATGAAATCACACCATATGTAACTTTTTGGGACTGGCTTTTTTTTTTTCACTCAGCATAAT +TCCTTTGAGTCATTCAAATTATTTTGTGTATCAAACACTCATTACTTTTTACTGCTAAGT +AGTATTCCACGGTAAGGATGTACCACAGTTTGTTTAACCATTCAACAGCTGAAGGACATC +TAGGCTGCTTTCAGTTTTTGGCTATTACAAATGAAGCTGTTAGGAACATTTCATTTCTTT +GGGATAAATACTGTGTGTCCCAGTGACACCCAGTTCTCAGTGTACATTTATGTCCCTTCA +GAGAATCCAACCATCTCAATTTGGGTAGCTGGCCAGAGGCCAGGCAACTTGTTCAGCTGC +CAACTCCTAGACTGAGTCCACCACTCATTTCCTGGCAGTTGTCAACAATGGAATCTCCAA +AGCTTTAAAAAGGTAGGCAAAACCCAAACTGAATCAAGACTATTTAGTTTTATTCCCAAA +TCCCAACAAACCAGGCTCCACTTGAATGTGCTTAATTGCTCTTATTTCCTGATATTTAAT +GCCAATAGATAAAAAACTTAAGGGCCATAATCAGGTTATAAAAATTAAAGTGATTAAAAG +AGAAAAATTTAAGTGTAGCCTTAGAAGCAAACTTAGACACATTAAAAGATGGAAGTGAAA +TTTCTGAGTAAAAATGAGAGTTACGATCTCCAAATAGTGAAAAACCTAAGGTTGGCTTGG +GAAGTCATGAGTCTGATTGGGTATAATCAGATCATATGACCACCCAAAAACAAAATACAT +ACAGAACATATACATCTTTTCTTTTAAGAAATGTATAGTACTGCTTATAAGCATGTTACA +GGTGTTAACAAAAACCTACTTTCCCCAGAGAATTCTATGTACTTCTTCACTATTTCATTG +TTTATATATTAACTGGTCATTTCCTCTAAACATGCTTTGAAAATGTGAGACATACAACAT +TTCAAAAGATTTTTATTACTCAGAGGTAATTCTCCTAGAATTCTATAATGTAAAAACAGG +TTGGCACCATCGTTAAAACCAGAAACATTTTCCATCATTCCTTTACATATCAAATAGTTT +TTAAAACACTGGTATAATTCTTAAAGTTGTCAGTAAAACTGATAAGAAAACAAAGGGTTA +AGTAAAACTATATAATTTTACTATTACAGTATATGAATTTAGTGGACTTAAAAATTATAC +TAAAAATAAATTAATTTCCCTATTATATTGAAATAAGCCCTTTAAATCTATATATTTTTA +TTTTTCCAGTATTCTGAAAGGATTGAACATCTGATTTTAGATATTCTGTCTTCTGGAATA +TTCGAATATTTTGAAATAAAAAATACTAATAAAAATATTCACAAAAAAGTAAAAAATTAC +ATTTAAAAATATTTGCATGAAATCTAATATATTGCTAAAATAAGGTAAAACTATAAACTG +TCATGTAACATCAGTATTTTAAATAAATTTAAAATTTGAGTAAAATTTTTACTGTGCAGC +CCTAAAACTCTCTGAAAAACATTTTTTCCAATGTTCTGAAAAGTAGCATGCCACCCTCTA +CTGCTAAGAGTCATAAAGCAGAAAAACCAATTCTTTGCTCAACTATTGCCACCTTGTGGC +TACGAGATGAGTTATATGCCATAGCACAGCTCCCAATTGCCTTAACAGATTCTACAAATT +TATATTGTCTAAGTGACATAAGAAGGATTAAGGTTTTAAAAATGGAGGGAAAATGGTACC +TGACTTAAATGGTTATAAAAATGAATGGGACGGCCTGGTGTGGTGGCTCACACCTGTAAT +CCCAGCATTTTGGGAGGCTAGGGCAGGCAAATTGCCTGAGCCCAGAAGTGCGAGAGCAGC +CTGGGCAATATGGCAAAACCCCATCTCTACAAAAAAATACAAAAATCAGCCAGGCATGGT +GACGCACAGCTATGGTCCCAGCTTCTCAGGAGGCTGAGGTGGGAGAATCACCTGAGCCAA +GGGAGAGAGGTTGCAGTGAGCCAAGTTTGCACCACTGCACCCCAGCCTCAGCAACAGAGC +AAGACCCTGTCTGGAAAAAAAAAAAAGATTTGGTTGCTACTCTAAAAACAAAACAAAACT +AGTTGAAGGGAAAGATGCATAAACCAATATTAAAGCTAATGAAGCAAAGTAAAAGAAAAG +TAGGTAAGTGAGCATGGGATGAGTATGGAACCTACAACCACCATACAGAACAATGGCATT +ACACTTAATGCCATTTAACTTCGGTTCCCTTTAACTAGTAACCCGAGTGTGTAATAGGAT +AAGAACTTCATGATGCATTGCTCTTGATTAAATTCCTGGCTGCAGGGGAAAGTTCTTTGT +AAGGATAATGTGTATGGGCTTATTTCTGAGGTCCACATGTAAGTAAGTCTACACTTTAAT +GACTATAAGAACTAAATCAATAGGTAAAACTTGGACTTTCACCATATACATATTTTTAAG +TCTAATAATAGGCCATCTGAGATGCTATTTTTCATTTGTAATTATTCAACCATCAAACTG +TTTAAATTTCATTCCAACTTAAATCAGCAAATATATACTCAATCCCTACTTAAGTGTAAA +GCATTATGCAAAGGATGAAGAGGGTGGACTGAAAATGGCCCCTTGTTCTTCAGGAACTAC +AGCTAGAAAACAGGATAAAACAGGTTTGTAAATGACTTTACTATGAGAGCTGTGGGTATA +CCATAAAGGTAGTAAAACACAAAACTCCAGAGCATTCAAAAACAGTTTCATCTGTTTGGT +GAGATCACAAAGGTCTAAGAGAGGAGGTGATTTTTACAACAGAATTTGCAGCAGGGAAGC +TAATTCCAGGGTAAAAGGTAAAGAAATAATGATTTGTTTAGGGAACAGCAAAATTCATCT +TCAAAAAGAATATTTTAAGCAGAAACCATTTTACAAATGAAATCTTACATACAATCCCAA +TATATATAGTGTAAATGTAGTATTTTGTTATTTTAAGTGCATTTTATGAGTTCAAATTGA +TAGCACTTACTATAAAGTCAAAAACTGTCAACATGCAGTTATGATAAAAATCAAAAACTG +AAATCAGGAATGAAAGATGATAACCCCAGTTTCCAATTTCTATATTTTGCTTTAATTGTC +GAATATCAAGAAAATCCACCTATTACACCCCATGAGTTGATACGGGGGTGAGGAAACATT +GTCATGCACTGTAGGTGGGAGTTCAGTACAAACAGGCTGTAACTCAAATTGTGTGTACAC +TTTTACCCAACATATAACCTACAAATACACTCTTGTAAGTACGCAAAAAATGCAAATGTT +CACTGCAACACTGTGTTAGAAAACAAAAACAAACAGAAACAACCTAAAAGTTCAATAATT +AAGGCCTTCCTACTTAAATAAATTATGCTACATCCACACCATGGAATACCAAGCAAATAT +TATGTAATGATAAGGAAAAATAGTCATACTTAGGTAAAAACTGCAATTTTCAGCAGCAGC +AACTAAAACATACTAAGTGCTTATTAAGTATCAGGCACTTGTGTTAAGTGTTTTAAATAA +TGAATTCATTGAATCTCATAAAAATCTCATGACATAGGGGGAAAAGGAGATACACAGATA +TTAAGTAATTTTCCAAGGCAACACAGCTAGTAAATGGTAGAGGAACCAGGATTTAAACCA +AGATTGCATGACTGCAGAATTTACACTCTTTAACTGTAATATATTTTAAAACAGTATTCA +TACTACGAACCAATTAATGTTTTTAAATATATATAGCAATACTTAGCTTATACTTACGTG +TGTAATATAAAACTCTGCAGCTATGCATAAAAAACACACTCTCCAGCCTTGAGAAAGTAA +GAAAAAGGGACTTTTACATTTCACATAATAACCTGCAGGGCTATGTAAATTTTCTTTCTA +AAGTAACCAAATATTACTTTTGTAAAATTTGTAAACAATATTTTTTCAAAAACCCTGAAT +ACACAATTGGCGTTTATTCATCTTGTAATCTCACGATACTGTTCAATTAAATAGGTCCAG +TAAGTTCAAAAGAGGTAAAGCAAGTTTTTTCACAAGTTGAATTCCTATCAATACCCAACA +ACTCCTCATATTCCTTACCATAAATATGTTAGAAAAACACTGAAAACTTCCAGTAAATAC +TAAAACTAAAACTAATGTGGTATTTTCAATTTCTTACTACTCTTAAAATTATTTTTACTC +AATTATTCTGGACAGGCACATTCAACTGACATGCTCAAGACTGTACTATTCTTGTACAAT +TGTTTGTGGACAGTGACACATATATTACAATTCAACGACAGGCCAGGTATAACTGAAGTT +CAAATATGCACTACATGTACTATTCATTCATTCACACATTTGACAAATATTTACCGAGTG +CCCACTATGGGTCAAGGACTGTGCTAGGCACTGGAAATACAACAGAATAAGAAAGACAAG +GTCTCTGACCTCCTGAAACATTTTCTACTGGGAAAAAAGTTAGTAAAAATTTTATTCTGA +TGTGTCATGTGTTACTCTGGCACCACAAGTTAACATATTAGTGATGACGAATGTCCTTAC +ATTTGGGATTAAAAAAAATGGCATGTGCATGGTTGTTTTCTGGTGTTTTTTGTTTGGTTT +TGGGCTTTTTGCCATGAAAAACTTAATTTTATTGTCTCTTTGAATGACACAGCTCAACCT +CTAGTTAGAGCATATACTGCCTTATGTTTTTAAATAGCATTTTATATTCATTCATTAAGA +AAAAAAATTATTTTTTAGAGTACTTTTAGGTTTACAGCAAAATTGAGAGTACAGTACAGA +CATATCCCATACCCCTCCTGTGCTGACACACACATAGCTTCCCCCACTGTCAACATCCCC +CACCAGAGCGGTACATCAGTTACAAGAGATGAATCTACACGGTTTGATAAATTAAAGTTC +ATTATTAAGAAAACAATGGGACTTCAAAGAACTGTGTAATTGTGGAAGCATCTCTGTGAA +ACTATTCTCAGGAAGGCAGAAGGCTGGAGAAGAAACGGCTGGGGCCACATAAAAGCTAAA +ATGCACTGAATAAAGCTTACTCTGTACCAGTCAATGTACTGAGAGCACGTTAAATGTATT +ATTTCACATAAACTTCCCAGTAACTCCAGTTGAAGCATTATCTCCACTTTGAGATAAGAC +AGCAAACTTAGATAGGCTAAGTAAGTTGCCCAAAGTCACTCAGTTGAAAGATGGCAGAAA +CTGGAAACCTGAACTGAGCCGAAGCTTTTAACCCAAGCAGGGTCTTGAATGGCAGTAGGC +CTCTGAAGCCACAGTAGAGAGATGCACCATTGTATATTTAATCTTGCAGGCAGTGTGAAT +GGAGGTTTAGAAGATTCTCAAGGAGAGCAATAAGTAAATAACCTCATTAAGTCTGATTAT +AGAGCCCAACTTTAGGAAGATAACTTGATCCACAGTGTGTGTAATGACCTGAACCAGGGA +GCAACTGAAGTCAGTGGTATCAATTAAGAAGGAGTAAAGGGGTTCACGTAAACTTCAAAT +GCTTCAAAGCTAAGAACTTGCTGAACGGAGACTACAACACAGCCTCCTGATATCCTCCTC +CCCAGGGAATTTTATTTCCATTAAACCAAGATGTCAAAGACTTGTGAATAAGAAATTGGT +GAACTGTACATCACAACCAAACACATTTACCCATCATCTAGTAGAATAATGTTTTCTAAA +CTGTGTTAGACGGAGAACAACCACGCAGGGTGCAGAGATGCTGCTGAGCCTGAGCTGGAC +TGAGAAAATCTAACGGATGTGCTGGGACTGCCAGGAAACACCCCAGCCTCCTCCTGGAAA +AACTGAACAGCCCAATTAGAACTGCCTTGGAAAGGAAAGGAAAGAGAAAAGGAAAGGAAA +GGGAATTCTGGGGACTCTAAAACACCTTGGTTGTTTCCTTCATTAAATAAACAGTACATT +TTTAGTTTCAAACACTTAACTTACTATACATGTGATGCTACAATTTTCACTCTTACCACA +GTTAACTCAGCAATTGAGAATTATTTTGGGGGGTTTCCGAAGGGGCTTAGAATGTGGTAT +GAATGGGAGCGAAGCGTGAGTGAGAAATATTAGGTAAGAAATAGAAAAACTCCTTTCCTA +TACATATATTTGGAAGGGAGCACTGAACTCTATGTTTCCAACCTTACTGCACTTAACTCT +TATGGCCTTACCTTAAGGATGGATCTAAAATCCATCCCTTAGGTGGCTTCAGGTCAATCA +TCGCTATTCTGCTAGTATTTTATGACTTCTCCATATATGGTAGAAAGAATAATGCCCCCT +CCCCCTACAAAGACATCCACATCCTAATCTCTAGAATTTGTGAATATGTTACCTTCCGTG +GCAAAGGAGAATTAACTTTGCAGGTGGAATTAAGATTGCTAATCAGCTGATCTTAAAATA +GATTATCTAGGGAGGCCAATGTAATCACAGGGATCTCAAAAGCAGAAGACGGGCGGGGGG +GGCGGGGCCGGGCGGGGTCAGCCAGGCCAGGTGGCTCACATCTGTCATCTGTAATCCCAG +CACTTTGGGAGGCCAACGCAGGAGGATCACTTGAACCCAGGAGTTCAAGACCAGCCTGGG +CAACATGGCAAAACCCCATCTCTACAAAAAAAAACAGAAAAAACAATTAGCCCAGAGTGG +TGGTGCACACCTGCGGTCCCAGCTATGAAGCAGGAGGATCACTTGAGCCCAGGGGGTTTA +GCAGTGAACTGAGATCATGCCACCACACTCCAGCGTGGGTGACAGAGCGAGACCCTGTCT +CAAAAAACAACAAAACAAACAAAAAAATCCAAAAAACAAAAAAGTAGAAAACAGAGGCAG +AAAAGACAGGCCAGGAAGAGATTCTCCTAGAAGCTACGGAAAAGAACACAACTTCACCAA +CACCTTGATTTTAGACCAGTGAGATCCCGTCTGACTTCTCACAACCCTAACAACAACACA +TTTCCTGTGTTTTACGCCACTAAATTTGTAGTAATTTGTTACAACAGAAAATAATAAACT +AATATACCAGGCTTCTTCTAGTCCTTGGATTTCAGAAAAATTTTGACATCAGTAATTGCT +ACTAAAATGACCCTATAACCCAGGACACTGCCAGTCTTGTGAACTGTTTGGTACTACTCC +CTAGGAAGAAAAATACAGAAATTGAGAGTTTATTTGTATATAATTCAATTTCATGTCTGC +TGAGTTTAATTATTAAAAACTTAGGCTTGTAATTTTATTTCTTCCATTTCATTTATCTAT +AAATTTATGGTATTTTACAAAAGTACTGGCTGAGACAAACGGAGATTTTACTTTACTTTT +TAAAAAAAGAAGACATTTACAAAAGAGAGGTGAAGCGCTGACAAGTTAAATCACTTGCCC +AAGTTCAGAAAGTGATTCATCACCCAGTCATTAAATTAACAAATGTTTATGAAGGGCCTT +CTACTCCAGACAGCAAGCTCCATGCTAGAGCTACTGTTCAGAACAAGACCCAGCAGAGCC +CTGCCTCTCCGTGTGAGTCCCATTCTCCTTAGCGTCCCAGGAATCGCCCTAGATCGCCTC +CCCAGCAGCGCTCCCCGCTGGTTACCTTCCCACCAGCATTCAATCCCAGGAAAACAAGCG +CAGTGTGGACAGACCCGGCCCAGTACGCAAATGCCACACAAAAGGACAACGAAAGGAAGA +AAAACACCAAGCACAGATTCTAGGGGCCGAGGGCTGAGCCACAACGCACCGCAACTCCGG +AAAACTGGGCCCCGGACCTCAGCTCCCCTTCCTAAGCCAGGCTCCGCCCCTATTCCCGAC +CCCGCCCACCGCGTCGTTGGCGTAATTCCCGCGACTCCCTCTCACCCGCCCGGGCTCCAC +CTTCTGTAGGGGCTCCACCTTCTGTAGAAGCTCCGAGTGCCGCTCCAACGCGCTCGCGAA +ACCGCCTGCGCGCGTCTTAGGCTCCTTGGCATTGGAACTACCACTTTCGGATCCACTCTC +AGTGCCTACACCCCGAAAGGGCCTGAAGAAGAGAAACACTCGCAGAAAATGGCTCTCGGC +AGCCACAGCACGGGTCCGACACAGCGCCGCCATGACTTCTTTACCTCTGACCTTTGACCT +CCCCTCCGCAAGCGCGCGGGTCACGGGGCGGAGCTATGAGAGGTCCGCCCCCCGGACGCA +GAGCTCTGGAGGCCAACGAGGCGTGTCTTCCTTTCATCTGGGAGTGGCGTGGGGAAGAAG +AGACTTAAGCTAAAATTGGTGGGCTAAATAGTTGGAAAGGGGCCTGGTTAAGTTTTGCGT +TAGAAGTGCGTTTAACTTGCAGGAATTTCGCCTTCCTGGGCATCCGTTGGACCCCATTGT +ACTGTAAATTCTGCTAACGCGACGCTCGTTCTCCCGCCCTGCCGTCCCCCCTACATGGCC +GCCAGCACTCGAGTTTGGGGTCTTCACTCAAATATGAGGGTCTCCTTGATTACCCTATTT +AGAAGTGGAAGCCCAAATGCAGACTCTCTGGCACCTGTTTTTCTTAGTACCATGTAGCAC +TTTCTAATATGCCACATATTAATATTAAATATTTAATAATATTTAGTGTCTACTCCCAAC +TTTTTAAACTTTGAAAAGAGGAACTTTGCTGTAGGGTCCCTAGCACCAGGCACAGATTAG +GGCTCACCCAACATTTGCCAAACCCTGCATCCAAGTTTGTCCTTTGCCACTTCTGCAGCC +AGTCCACTCACGCCACAAAAATAGTTTTTCTGAAATGTTTTGACACCTCTAGATACCTAT +TATCTAACTTAGGAGTTCAGAAGTTTTGGAATGTCCCTAAGTATTGCACCGCCGTAGGCC +CCCACCCTCACTCTGGATTTTCTTTCCCTTTTCTCCTGCAGTGTTAATTCCCAAAATTTA +CCCACCCTGTTCAAAACAGCCTAACATCATTCTTAAGTGTTTATTAATTAGTTGTCCGTC +TATCTTTGACCCAGCAGTTTAATATTAATCCACAGTTAGTTTTATTTTGGGGGCACACAC +CTTTCCAGTTCATTTGCAAGTACTTCGAGAGAAAGAATTTTTATGATCACAGACCCTATT +TTAAGAATGCCTTGACTATGGGTTTTAAGCTTTTCTGATGCTCTCTAATGGTACAGATAG +TGTTAAGAACACGAAGTACACTGATCTCAGAATGGTGCACAATTGTATGAATCACATAAA +ATTATTACTAGCTAACTGTATGGTAGTCCTTACAAATTCATTAAATTCTCCAGGTGAGTT +CTCCCTCTTGGCAGTTAAAACTGTTTATCTCCCGAGACTATTAATGGACTCTTGCCTAGA +ACATTATTTTCTACGGATAGTGCTACTTCCACTTTTTTTCAGGAGAAAGTGTGGTAAATT +GTAAAGAGCATGGCCAGTGGTCTTCAAGAACCCTCAGTCTGACTGGGCAGGGTGGCTTAC +ACTTGTAATCCCAGCACTTTGTGAGGTTGAGGAGGGAGGATTGCTTGAGATGAGGAGTCC +GAGACCAGCTTGGGCCATAGCAAGAACCAGTCTCTACCAAAAAATAGAAAAATCAGCCTG +GGGCAGTGGTGCATGCCTGTAGTCCCGGCTACTTGGGAGGCTGATGGAGGAGGATCACTT +GAGCCCAGGAGTTTGAGGCTGCAGTGAGCTATGTTCCTGCCACTTCACTCCAGCATGGGT +GAAAAGTGCAAAACTCAAGTATCCGTAAAAACACACCCCTGGCGTGGTGGCTCACACCTG +TAATCCCAGCACTTTGGGAGGCCAAGGAGGGCAGATCACCTGAAGTCAGGAGTTCGAGAT +CAGCCTGGCCAACATGGTGAAACCCTGTCTCTACTAAAAATACAAAAATTAGCTGGGCGT +GATGACACATGGCTGTAATCCCATCCACTCAGGAGGCTGAGGCAGGAGAATCACTTGAAC +CCAGGAGGTGGAGGTTGCAGTGAGCCAAGATCACACCACTGTTCTCCAGCCTGGGTGACA +GAGCGAGACTCCAGCTCAAAAAAAAAAAAAAAAAAAAAAAATGAGTAAGTTTGTATCAAA +TGACTTCAAATTTGGCCTTAGTTCTGTCTTTGGTAGAGGATCAGAAGCATCAAATGAGAG +GGACTGTAAAGAACTGAACAAGTCAATAGGGGGATGTCCGCATAACTTTCTCCTTGCCTA +TACAAGTGCCAAGAGTAGCATCCTCTGTAATAGTGATGTTTTCACATACGCCATCTTAAG +GATTCTGATCCTGCTGTAACCACTCCTTGCTTTATTAAATACAGGCCTGGCTGGGCAGCA +GTGCACACCTTTAGTCTCAGCTACTCGGGAAGCTGAGGAGGGAACATCGCTTGAGCCCAG +AAGTTTAGGGCCAGCCTGGGCAACACAGTGAGACCCCCACCTCAAAAAAGCCAAGGAAAG +TGAACAGAAAATAGTTTCATTCTACTGCTAAGTTCAAGCCTAATACTTTACAGCTACTGG +CTTTGGTCTTATCTATAAAATGGTGACACTGCCACATGCCTGAGTAAAGAGTTAAAGGTG +ATGAGTGTAAGATGCCTGGGCACTTAATGAATAGTAGCTATTGACGGCTAGGTGGAGGTG +ACCATGAGTTTACTAGAAATTCATGCCTCAACCATGTGTGCAAACCAAGAAGAAAGGATA +GTGTCACAAAGTTCTTAGGATGTCGCTTCACCAGCTGGAAACTTCCATGGCCTGCAGCGC +CTCTGCTGGAGTTTTGCTCATGCCTGCTGGGCTCATTCTGCCCACTCTGCCCAGTAGGCT +GTGCTCATCTTGTGCTGCTGGCCCAGATCCCACACCTGCCAAGGGTGAGCCAGGCATGGG +CTGGTGAGGGGTGCGTGAGCAAGTGAGTGCAGGTTCCAGCCACTGCGCCCAGCCAGGCAC +ACCAGCTGCTGCAGCAGGGTGAGCAGCTACAGGCACCGGCTCTGTGCAAGGCTGCAGCTG +GACCAGATGGACCACAACCAGCTTCTGCAGGCACCAGTGTCTGGGCAAGGGAAACGTGGT +AAAACCCAAAAGCTCAGAGATGCCAGCAACCTCAGAGTCCCAAAGAGGGTGTTACAGCAT +GTCACAGCCCTGGCTTGGGGAACCCCAAGGTGTGGGCTCCCAGAAGGGCTCAACTCTTCT +CGTTGCCTGCAATGTGGTGACCGGCGGGGCGGGGAGGGGGGTTGGGGGGGGGACATTGTT +GGGGGGTTGTTTCAGCCCGTTTGTGTTACAGCTCTTTCAGTCCCACCACCCCACTCCAGC +CCATGGCTCCTCAGCTGGCCTGGCTCTGCTGCTGCCTCCTGTCATGTGGGGCAGCTGTCT +GGTGCCGGTGAAAGGTGGGAAGGCTATAATGTTATAGCAGCTCTGGCTCAGGGAATCCCA +AGGTCTGGGTCCCCAGAAGGGTCACCACTCTTCTCTCCTGCAGTCTGGGAGCGTGTCACC +GCCCCAGCTTGGCAAGCCAGCCAGGAACATGTTACAGTTCCTTTTGCTCCCGCTGTTCAG +CAGGTCCTGAGTTCTTGTCCTGTGTCCAGGAAGAATGAAGTCACATGGACAACCGTAGGG +TGAGCAAGGCAGAGAGGAGCGTTATTGAATGACAGAACAGCACTCAGGAGACCCAAAGTG +GTCCTTTCTGCAGGCAGGTTGTCCTGATGAGTGTTGAGTCTGGCTGAGTGTGGGGTTTTT +ATGTGCTCAGAATGGAGGAAGGGTGGGCCTGGAAAAAACACCATCCGATTAGCCGAAATG +CATTAATAGAGTTCTCGCTCTGGGTTGTGGGCTCTACCTAAAACTGGCAGCCTGGCCCCC +AGGCTTCAGGCTGTCCCTGGCTTGAGGGTGGGGTTTCAACAGGGACCCACCCCTTCCCTC +CTAGGAACCTGCCTCCTGCCACCATCAACATGCCATCCAGAGCACCCAGGCTGTCCACAC +CAAGCTACCCTCAGCCCCTGGCCACCCTCCCATGCTCACTGGTGCCCATAGTTGGGAGGG +GGCCGAGGTAGCAGGAACCTGACATGTCAGCACCACCCTGAGGATGCACACACCTGGCCA +GGTTGTGACAGCACCCAAGCTCAGCCACAACTTTGCTCCGAACTGGAGCAGGCACTTCCA +GGCCTGCATGGGCAGGGGACTTTCCAGGCCCCCGAGAGCACACAGATGCCTGGATCTGGA +GCTGCAGCTGGGTGGCTGCAGCTGCACCCAGGAGCACAAGCTCCTGCCCTGCCAACATGG +TAAGGCAGGGTTCCTGCTGGGATCACCTATTGCCGGCCCCTGCCACTTCTGCAGAGCCTG +CAACCCCCCAGCCATGCTTCCCTTGCTGCAGCTGGTGTCCTTGCAGCAGCTGCTCAAGGA +GGGCCACCACCATCAACAAGTCTGGAGATACCGGTTGGGAAGCTATTAGTATCACTCTAA +AAATAGTCATTTCACCCATAGAAATGGATAAGATCATTAAGGGGATCATGTAGAAGATAA +CAACAGATAGACAATAGCATTTAGGAGCTGGAAGAATTCTAATACTAAAAAATAGTCAAA +ATGGAAAATAAGAACAGAGAATCAATTCTAGAAACCAAGGAGAAACTTTAAAGCATGCTG +GAGAGTGGTAAAGTGAAAGATCACGTCCATTTACAAATATTCAAACAAAACTGTATTTGG +CTTTTTCTATATGATAGAAGAACCACAAAATTAATAAAATAAACTACCAACCAACCTCAG +TAACATCAAAATTACATGAGAGCTGGCAAGAATTTTAGTTGCCAAATAGCATTTATTTGA +GTACAAAATCCTGGCAGGCAAAAGCACTTGCAGACCCGACTCTCTGAGAACTTACAAACA +AAAAGTGAAAAGCTCTTAGTTCATTTTGAGTCAGAACAATAAGGAAATTATGAAATCTAA +GATGTGCAGGTTTACTTAAAAGTGATAATGGTTTATATTAACTGTGGCCCACACAGGGTC +TCTCTAATCTAATGAAAACAGGACAGTCACTGAAAATAAGGACTAATCAATGGCCAAATG +TTTCTTCACTATGGGCAAAAATGTGATTTCTTCATCTGGGCTTTAAGAGCTATAAATAAA +ACACATGGCCGGGTGCATGCCTATAGTCCTAGCTATTTGGGAAGCTAAGGCAGTAGGATT +CCTTGACCCCAGGAGTTGGAGGTCAGCCAACTCTAAACAAACACAAACATCATTCTGACA +AATGACCTTAATGTAGGATCTCTTTGGACACATCTTCAGCAAGCAGTCATTTAATAAATG +CCTTCTGATAGGCAGAATGTAGCTGCTCATGGCTCTTTAAGTATCATATCCAGAATATGA +AGGGTTTGGAGAGAAGTTGCATAATGGACTTGCCCCTTTCCTCAATGGGCAGGTAATGTA +TACAAAAGAACCCATACCCAAATTATAGCATTTTTATTTTCCAATACTATACAAAAAATA +GACTGTGCATATCTTAACAGATCCAGATCCAAATTAAATACTTTTTTTCTATTTCAAACT +ATTCTAAGTTGCTAAGGTGATAATCCAGTTTTGAGCTCTACTCTCTTCCACTGACTACTT +GGCTCTCATAAGCATAAGAATTCTTGCCCTATTTCCCACAAACTCCATAAATTGACATTT +CTTTTTGTAAGAAGGGGATATTTTCTTCTACACTTGAGTCCTTACATCTGTGAGATTTCA +TAAGTATCTGAGATTTCACACTCTTGCTATTTTCTTAGTGTCAAACACAAGAGGAACCAG +GAACTGTTTCTGGCATTTCTACTAATTACTATGTTTCTCATTCTTTAAATATCTGTGAAT +TCATAATATTGAATCTGCCACAAAAACCATTTTGAATATTTCTAAATTCATGTTTTTTTC +TAAATCCATCCTCACTCTTTTTAATACTTCTTTCAAGGGGCAGAGTACTTTACAGTAGAT +TACTTTGTTTCTTAGATTAAGTATAGGTAGATGTCTAGAAAAGTGATTCTCCATTATTTT +CTTTCACAGCCACCCCCAATACCCACCTTCATCCACTCACCCCACTTGCCACCCCCATTT +CTATCACTTTTCCCTTTTTGGGCAGAAAAGAGACTTGAGGGTATTTCACTCATCTAAAGA +AATTGCCACTTTACTCCATTTTGCCTTGTTGAAAAGTTAGTAGCAGGGCAGGATGCTCAA +GAAACAATGTGATCAAAAGAATATGTTTGAATTTTAAGAAGTAGACTAGTTCATAGAAAA +AATAATTTAACACTTGAGTAAGCACAATATTTCTATAGAAAGACAGACTTCTACAGATCC +ACTCCTCTGAGAAAATGCTTCAACAGCCTGTGCCTTAAAGCCCTTATTTAGAATATGTTA +ATATGATACCATTAAGCAATAATTTAAGGATGGTTAAAAAAAAATTTTTTTTTTTTAAGC +ATAGACTCCAGTTGATTCGGTACAACAAGCTGTTTCCAGACCACTGGTCTCATAATAAAT +ATTGAGACCTATACTACTGATAGATGGAATTTATTAAGCTTTTCACATGTGATAGCACAT +AGTTTTAATTGCATCCAAAGTACTAACAAAAACTCTAGCAATCAAGAATGGCAGCATGTT +ATTTTATAACAATCAACACCTGTGGCTTTTAAAATTTGGTTTTCATAAGATAATTTATAC +TGAAGTAAATCTAGCCATGCTTTTAAAAAATGCTTTAGGTCACTCCAAGCTTGGCAGTTA +ACATTTGGCATAAACAATAATAAAACAATCACAATTTAATAAATAACAAATACAACATTG +TAGGCCATAATCATATACAGTATAAGGAAAAGGTGGTAGTGTTGAGTAAGCAGTTATTAG +AATAGAATACCTTGGCCTCTATGCAAATATGTCTAGACACTTTGATTCACTCAGCCCTGA +CATTCAGTTTTCAAAGTAGGAGACAGGTTCTACAGTATCATTTTACAGTTTCCAACACAT +TGAAAACAAGTAGAAAATGATGAGTTGATTTTTATTAATGCATTACATCCTCAAGAGTTA +TCACCAACCCCTCAGTATAAAAAATTTTCAAGTTATATTAGTCATATAACTTGGTGTGCT +TATTTTAAATAGTGCTAAATGGATTAAGTGAAGACAACAATGGTTCCCCTAATGTGATTG +ATATTGTCATTTTTACCAGCTTCTAGATCTAAACTTTCAGGCTTTTGAACTGAACATTGA +TGACAGTGTTCATAGTTCAACCTACTGAACATACAGTGTGCTTGATTCAGAATGTTATTT +TGTAGAAATTAAAATTTTAACCTGGTGAAAAATAAGTTGATATAAGTGGTATAATAAACA +ATACACTGAAATGGTTACTGTCACAAACGGTGCTAAATAATGATATAGGAGGTTCCACTC +TCAAGTCACCTAGAAGTTTGATTACATATTGTTACTTACAAAACTATAATAAATTGGATG +CACAGCTGTTTACTTCAGTCTGGTGTCTTCAACCAAAATATGTACCTTATACCAAAACAA +TGCTTATTCCAAAATATTTTTTGTAGCTAGTAGTTCTTTCCTTGGAGGTAAAGAAAATAC +ACCCAAACTTTTAATTACCAGGATTCAGAATATTTAAGAGAACAATTTTAGTTAAGAATC +AAATATACAGAGATTCAAAGAGGGGAAAAAAAGGAAATATTATAGAAGACAAAGGTCAAA +CTGGCATTCCAGATCTGGAGCAATTTTGTAAAGCAGGAAAACAACTATGACAATCTGTAG +CTTCTTAGATCATTATAGTGAATGTCCCCATTTACTATAAGTGTTTTTATAATGGTGTTT +CCTAAATAAAGGAACATAAATGTACACTAAAGGGTGTTTCCCAAGAATAGAGGTGAAGAT +ATTTTCATTTTGTTTAACCCACAAACTATTTGGTCAAAGGAATATGTAAAGCTAAATAAA +AGCACATCTGGTAGAAATTCATGGCAATGCATGTTGACAAGATGTGCTTGGACCTCGCTT +GCAGCATCTGGCAGTGGGTAGCAGAACAAAGGTAGGAATCTCACAGGCTCTCCTGTGTCT +TTTCTGGAAGAGGCTCCGTGGTGGTGGCACTAGCATTTGCAGCCGAATTCAAGACTTCTC +CAAAATCACCACCAGCAGGCTTGGTTCCCCCTACTTTAGACTTAAAAAAAAGTTCAAAAA +AGGGAAAGACATTATGAAACATAAAACTAGCTGATTCTGCATAAAGTAACTCTAATTCAC +TTTCAAGAACAAATACATCAGCAACCTTATAGCTCAGTGATTATTATATATGTATGGAAT +TTAGTATTGTTGCAATGTTCAGTGTGGTTTTATAGTAAAACTCATGCATTCTCCCTTGCT +GAAATATTCAGATTGGTAAATTCTACCCCTTCCCCTTTCCCCCTGCTCCTTGTTCTTCAC +AGGAAGTCTGTCTAGAAAACTTTGTAAGGTCTATTATTTTAAAGTACCTAGTGAACTGTC +TGTCTCTACACTTGCATAACATTTTGTATTGCATCGAATTGCTCATTTAGCTACACTCAT +TCAAGAAATATTGAATACAACATGGGAAAGAAATATATGTTTTTTTCTCAGTTACAGTAT +AAGCTTTCTAACCCTTTAATACTTAAAGTGTGGTTCAAGGACCTACAGACTCAACATTAC +CTGGGAGCTTATTAGAAATGCAGGATCTCAGATATCCTTTCTACCCCACCCAACTCCAGC +TACAGAATTGAAATCAACACTTGAACAAAATCCCTGAGTTGTTCATGTGCACATTATAGT +TTGTGAAGCACTACTCCAACCTATCTGGCCTGAAATTTTGCCAATAAGCATTTATTTCAA +TATATCTGCCTTGCATTTGTATAATACTTTTTCAAAACCCTTACACATGTCACTTTATCC +TTTTCAATGCTAATCTGTATATGCTCTCTCACTGTTACACTGTCCAACAGGACAGCTAAC +AGTAAGAAAACAGTCAGTGACCATGGATGCAAGAAGCTTATAGTGGGTTTGAACTTGACC +TTGCTCTTAGCTCAATCTTAATTGAGTGGTCACAGACCCCTTATTTTCACTCTCATTCTT +TTTGATCTACCATCCAAATTGTTTGGGAAATGCGAATAATGTGTGTTCATTGTTTATTAA +ATTTATTAAAACACATTCCTTAATTATAGTATCAAATCTCCTTGCAGTTCAACATGTCTA +AAACTGAACTCCTTCCCCCGACAACTAGCCCCTTCTCTATTCTTTTTTAACACTTTATAT +GGCAATAGCACCTACCTAGCTGCCCCAGCCTGACACCTGGGGTTGTCCTGGATTCTTATC +CAACTTGTTCTACATCCAATCAATCTTTTTTTTTTTCCGTGTCACTTCTCACTTCTAAAT +AGCTCTAGACTTGGTCCCATTGCACTAACTTAATTCACTCTCCATCATCTTTGGCTTGGA +GTACAACTCCGTCCTTCCATCTAATCTGCCTGTCTCCAATCGTTCTCCCCTTTGATGTGC +AGGGCAGCCACTGATCTCTCTAACATTTACAGAAGAATGCACCACTTGGGTTGTTTAAAA +CCCTTCAATGGCTTCCCATTGCCCCAAGTTCAAACTCTGCAATGTGGCCTACACATCTCT +CTAGCTTCACCTCCTGCTCAATATCCTACAGCACAGTGAAGTTCTTGGTGGTCCTCAAAA +GGGCCCTCAAACTTCAAACATTCCCTTCAACCTAAAATCCTCAATGGACATTACTGAGTC +CTCTAAGAGGTCTTCTCTGACCTTCCCTTCCACCAAGCCAGGTGAACTTTCTGCCACTTG +TCCTCATCACACCCTCAGCTTTTCACATCAGAACCCTTACCTCACTTTAGTTTCATTGGC +CATTTAATTGTCTAGGCATCTTGCAGAAGGGGTCCATGTCTCTCTTGCTCACTGTGGTAA +CTCTGGTGCCTAATACTGATTGACTGGCACATGGCAAATGCTCAGTAATCACAGATGAAT +GAATCAACCCAAAATCTAAATGGACCTCATGTTTAATTAAATATAAATGTAATTTAACAA +AATTATATCCCCAGCATGTAATTTTACAGCTTCCTTAGGATACTTGGGGTATCTGTTTAA +TACGCTATCCTTTTTTTTTTTTTTTTTTTTTTTTTTTGAGACAGGGTCTGGCTCTGTCAC +CCAGGCTGGAGTGCAGTGGCATAATCGCTGCTCACTCTGCCTCCCGGGCTCAAGCGATCT +TCCTACCTCAGCCTCCCGAGTAGGTGGGACTACAGGTGTATGCCAACACATCAGCTAATT +TTTCTATCGTTTTTGGTAGAGACAGGGTTTTGCCATGTTTCCCAGGCTGGTCTCAAATTC +CTGGACTCAAGTGATCTGCCTGCCTTGGCCTCACAAAGTGCTGGAATTACAGGTGTAAGC +CACTGCGCCCAGCCAACATATTGTATGTTTTTAAATTACACTTTTTAATCTGAATGGTGC +CTAGTCATATTTTAAAGCAGACTTCATTACAATTTATAGAATCTAAATATATTCAGGAGA +GTATATAGTGAATGACCTGGAAGTTTCTCCTCATGTCCAATGTCAAAAACACATAAGATT +CCTGGTTTTCCAATTTGCCATTTCAAAAATTAACACTTGGGGCAGATTTCAAGGAAAGGC +TATAACAGTCCTAACAATATTGAGAACTGAATTTTAGTAATCCTTGACTTCCTGCAACTA +CAGTTTGCTTTCAAATATATGACTTGGCACTAAGAAAAATAAAGCAGGTCTCTTGAAATG +ACATAGAAGAATGACTCTTATATATATTGTTACTCATCAGATGCATATTGAGCAATGTGC +CAAGAACTGTTCTAAGCCTTTGAGAAGTATCAGTGACCAAAAAGAACAGGTCCCTGCATT +TATGGCTCACAAAGCACCCTGCTAGTGAGGGCTGAATGAATAAGCTGTAGGACTGTGTGT +GTACAGTGTAACTCCTCTTCTGAAAAAACATTCATATGTCTGCATACAAACAGAAAAGGT +ATGTACTAACGTTTGTATGTTCAAGAAAAAAAACGATCCAAACATCACACACCAAGGCGC +CTGTCAGGGGGTGGGATGGTAGGGGAGGGATAGCATTAGGAGAAATACCTAATGTAGATG +ACAGGTTGATGGGTGCAGTAAACCACCGTGGCACGTGTATACCTATGTAACAAGCCTGCA +CATTCTGCACATGTATCCCAGAACTTAAAAGTATAATAAAAAAATAAATTAAAAAAAGAT +CCAGATCACTGTAGAGTGTTTTATTTCAATAAATGTACCCTGCTTTTAAAGATGCATTTC +GTGACTCAAAGTTCTGAAAGACTAAACTGAATATTAGTTTTTAAACTGACTGATATAAAA +ACATTTAAGATACTAGTTTTAATCCTTAAAATATATCCCCTATAATTATCAGAGTTAGGA +AGTAATGAAAATATGGGTTTTATACAAACTCCGTAGAGAGGGTCGAGGAATAGATGGGAA +CTAGACAACTTTTGAGGTTGCCTGTGATCCTAAGAGTTGATGATTTTATAGCTTTGAATA +TAATCTCAAAGATAATATAATTTACAAATCAATAAAGCTCATTATTATGGGGAAATGTTC +ACCTCCACTAAAATCAAAGAAATCAAAAAATAAAAACAGTGAATCATAAACGATCATCAT +GGCATCATTATAATAAAAAAAATGTCCAACAATTGAGGACTGAACAAATAATATCCATTA +TAAGGTAATACAGGCCAGGCATGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCC +GAGGCGGGCGGATCACGAGGTCAGGAGATGGAGACCATTCTGGCTGACACAGTGAAACCC +CATCTCTACTAAAAATACAAAAAATTAGCCGGGTGTGGTGGCACGCGCCTGTAGTCCCAG +CTACTCGGGAGGCTGAGGCAGGAGAATCGCTTGAACCCAGGAAGTGGAGGTTGCAGTGAG +CCAAGATCACGCCACTGCACTCCAGCCTGGGCAACAGAGTGAGACTCCATCTCAAAAAAA +AAAAAAGTAATATACAAGCAGCCATTGCACATAATATTGAAAGAGAATACTTACTGATAC +AGGAAAATGATTATGATGTATGGCTACTTCTTTTTTAAAGCGTAACAGCATAATAGCACA +TACATCTATCACTGTCTGAGTGGTAGGACCAATTTTTTGTTTTCTTTCTTGTGCTTCCTA +TATTCTTGTTAATTGTTGACAAGAAAGTTATATTAAATTTTGTCCACCTACAAAGGTACT +TGAAATGAATAAAGCAAAAAGCAGCACAAATTTCTAAAGTGCCATTTCTTTGTAAATTGT +ACATTTCCTTTCAGCATGTGGCATGCTGCCACACTACAGCATACACTAAAAAGATATTAA +GTACATAACACCTTAAATGTCCACTAGTAACATAAGGAGTAAAGTTATTTACATTCTTTA +GATATTTTTAGAAAGAAATATTAATGTCAATGATTTTCGCACAGCAAAGTTAATTAAGAC +ACCAGGCAATGTATCAAAAAGACCCTGTTCATCTCTCTACTTGCCTTTAAGTTTTCGACC +TTTTCTTCAAATGATTTAAAAGTTGGGGAGTTTCTATGGAGAGAAAAGAAAAACAAATAG +TAAATACAAATACTGAAAAAAAATCCAACTAGTTTGAAAATATAATTGATTCCTCTTCAA +CATTATTCTCAATCGGCAAAAGAACAGATATAATCTGTACCATATATGTGCAGGTACATA +CAAGTATTTATAATGTAAGATTCTCAATTTCTGATCTAATATTTTAAGAGTATGCATTTG +ATTCCATGAACAGGGCCAGTCTCAGACATAAGTAATATAGATATGGTCAAGTACGTGTGT +AAGGAGAGGTAACGAAGCCGGGTAAAATAGCAATTCTGTCACTTCCCCAACCAACTTGTC +ATGGTACAAGAAAATGCCACCATTAGATCAGTTTAATTTTGGTTAAGGTACTACGCTCTA +AAATCCCTATTTTGATTCACATCTTCCCTGGCAGAATTTCTACATGAACACACATCACCT +AAGTGGGACAAGCTTATGAGGTTCAATATCAGGGAGCAGCATAATAGACTGGGAAAGCAG +GGACCAAAAAGAAGGGGGAGAAGCATAGAAACGGCTTTGCCTACTTCACAACTCTGTCCC +AAAGGATGAGGAGAGCACGCTGAGCCCACAGGACATTCATTCATCCATGTTACATTCACA +TCTATCCATATTAATTAAGGAGGATCATAGCGCCTTTGTCTCTCACAAAGGCGCTTTGGA +AACAGGGTTTCCAATGCTGTTATCCTATCCAACTGACCTTGAATATCCTTCCTACTACCA +AGATGAAAAATGCAAAGAAAGGAAAAGGGGTTTCTTCCTTCCCACGGTGGTGATGGCAGA +ACAGTTAAGCCAACAGCTCTCAAAGTGTGGGCCCCAGACCAGCTGCTGCTGCAGCTATCA +GGAAGTCATAAGCAATGCCAATTTTCAGGTCCCACCCCAACTCTACAGGATCAGAGGCTC +TAGAGGTGGGGCCCAGCAAGCAGCGGTTTCACAAGCACTCCAAGTGATTTTGATGGACAC +TTAAGTTTAAGCCAAGCACAGATTGTTAAAAATCCTCTAACTCTCTAGAGAGGTTAGGTG +AGGTAATATCACTTGCAAGTGCTAATGAAAGCAGATAGTAGAATTAAATCATAGTTGGCT +CCAAATGTCACAGTGGGATGGGGGAAGTGAAAATGGGAAGGATGAAGAAAAGGAGAATGT +AACTAAAGCGAATGCAGACAGAGGTGGCGGGACAAAAGAAGGTTTGTTAACAAGTAGTGC +TCACTTTGTGAACAGATTTCAGACAGGAAACAAAGGTTTTACAAAATAAAATAGAAATAA +TTTTTTTAAAAACAAAATCAAAACATTTAACGGATCTCTTGCACCCATCCCAACATCAGA +GGAAGTGTAGCTGAAAACTGATAGAGTGTTAAACACACAGCTTGTTTCAAGGGGAATTCT +AGTTCCCTAATTCAGAACAGTTCAAGTTAAACATCTAAATAAAGAAAAATAAAGCATAAG +ACCAACTACATTTCATAAAAATATACTTTACCTCATAGCAGGCATGCTAATTGAATGCTG +AATGGAACGTATACTAAGAGGCAGCATTAAAAAGAGATAGAAATAAGGTTAGTATAGTGG +TGCTTCAACATTATTAAAAGCTGACAAAACTTAGCTCCCCAGGAGCTTTATTCTCTTGGC +GCCATGAAGAATTACCTACTTTTTGAGGTGGAGGGGATCAAAGTTATTCCAACATAATTT +ACTTTTATTCAGGAGCCAATTAATTCCCAGGAGTTACTAGAGCTAACAATACCACCTTGC +ATTTTTACAGCACTTTGAAAACTAAAGTGCTTTCACCCGGAGCTGTAAGGCATATAGGTG +TTAAATGAGTTACCGTAGGTCACAGCAGAATCAAGAATAGAACTTGGGTCTAATTCAGTG +TTTATCGCCTCCCCTCAAAAATGAAGCATGCACACACACACATACACACATACACACACA +AGCAAGGCCAGGGAAGGGCTCTTAGTAAGACAAGGAGGCAACTGCCCACTCAAGGACAAT +GCAGTTCACTGACCACTCAGGTTCAAGGTTACCTACTCTTAGCCATCTCCCATAAAGACC +ACCTCATGAGATGAGAGTGCCTTCATTCCTAGGCTCGTAAAATGATTGTATTCTGCTAAT +ATTGTTACTATGCTTATAATAGTTTGACCACTGGCACGACTTTGGTAAATAAACTTTCCT +TTGGGTAAAGTGTATAGGTTCAAGGTATTAATTCTCAGTTATATTTAAATATTTTGTGCG +CTTATGATTTCCTTTTCTTAAAGACTCATTTGGTACAAATGATAACGTGTCTTCAATGTA +GGTCCTCAAATCTAATTTTGCATTAATATCTGATAACATGGAGAATGATTGTGATATATG +TCAAATATGCTGGCAATCTGTGTAATCAGGATTATCAATGAAATATTTAAACACCTCTGT +ACTTGATGTCTTACATAACAGGAAAAGATGCATGTAACTCAGTATTCTCTCTATCCTACA +ATGGTGGTCAATACCTAGGGTATAAGAGTATAATAATCTATTCTGGGAGGAATTTGATAA +TTCTTTTCCTACTTTGGATCTATCAAAGTGTGCTGGTCCCAATCTCTAAATTTACAACAC +CAGAACTCTAAGTATCACCTGTTCTTCCTCAGACCCTTCTGCTGAAGCTGCCTGGAATAG +TCACATTGCCACAAACCACCTTCTACCATAACTGATATGATAGGTGGATCAGTGGAGCAC +CACCCACCACTGCTAACCTCCCAGTGGCCTACAAATTGTTTGGAATGTATGAAAAATGAA +GGAGTGAAGACAATTAAGACTCTTATCCTAGCATATTGTAATTAGGACACTAAGCTGCTG +GACACTTAGATGTTGAAGAGGATCTGGTGGGACCAGGTGAAAGCTGACAGAACACAGAGG +AAACCAGTTCCCAAAGAAAGAATCGAATATAAGCACACAGAGAGGTAGAGCAGATGAGGT +CAGGAGAGGTGATCATGCAGGGAATCCAGCAGGATGGAAGAGGAATAGGTTTCTTGGTTT +CAATAATAGAAGCTACTTCAATTTCCCAGTTGATGGAGCTGGTTTGGGTGGAGCCTGGCC +TTGCTTTCTTTTCTCTCCTTGAATTACAAAAAAACTTTGTATTTGTGCAACACATTCTTC +TTTTTAGGTGAGCTAAAAGTTACATAGCTTTCTGTTCCTAATAATCAAAACTCTTCATTA +GGACATTCATTTTGGCAGAAATCGCTGAAAAAGAAGGTAATGGCCAAATATGTGATAAAT +TCCTTGTCCCGGGGACCCACACATTGAATTTGGTAGTATCAACAAAATGTGGAAACAGGT +GGATAAGTAAGTGCAAATTTCAGAATTTCACAGCTAATTCTAGTCACTGTCCCTAAGAAC +CCATGTACAATATCACTTCCTCCAGCAGTGGATCGGTTGGGCTCTATACCACTTTACCTA +GCATGTACCTACTAAATATGTTTCAGTGGTAATATATAAGGAAAGGCAAGGAAGTGACTA +GACTGTTTATTTTGTGAAAAAAATCACTGAAATGAATTTGGTGTTGAGCACTTTTCTGTA +TGCATTATATCACACTTGAAGATAAATATACCCATTAAACAGAATAAAATCAGTTAACAG +AGTCAAAGTCAAGGTCTCTCTGCTTTTATGGTAGCTATTTTATAGTAGGAAGAAAAGGAG +CACACATCAGCTTCAATTCTATCTGGTTGCTGGATCCTCCCCATAATCCATAGTTAGATG +AAATTCAATTTTGTTGGTAACTAGTTGTAATCTAACTATAGGGTGGCTGTTCTTTCATTT +CTGGCTTCTCTATGGCAAGTTACACAAAGCTTCAACTTGCTCATCATTTTCAGTTTCATT +CAAGCTTAAATGTAATATGGAAACCTTCAAAAGTAAAAAGTCATGTTGCTACGGGACCAG +AATCATCTCTAATAGATAGGTTGTAAGAATCGGTTACCATCTATAAGGCACATTTTGTTA +AAAATGTTGCATCTTATTTGTAACCCCCAAATACATTAATCTGTAATCAAACTAGGAATG +CAAACATGGGCTCCTCAAAACACTGAAAAAAAAAATCAGGATAATCTGATTCTCACTAAG +TACTTTTCAATCTCACACTGCATTTACTCTTACTTTGAAAAAGTCATTTTTTTAAAACAG +CTGAATTGATTTTTAAAAAATATTCCTTGTTTCTAACAGTTATCTGATGCTTTCATGCTC +AATAATAATAAGAGAGGAGGGGGTAGAGGGAGGATAAGGAAGGAAGTAGCAGCAGCGGGA +GGAGGAGAAGGGAAAGTTAATGGCTAACATGTTGGACTGCTTACTATATACCACGTATGC +TTTTCACAGCTATTGATGTACTATTATTCCACTTTGCCCTCACACAATCTTTTGATGTTG +GTGATCACAGCAGCTATTGTTCAAAGTGCTGGACAGTGCCTAGAGGGGCACTGTCTTAAA +CCACCACTGCTCTGGGGAGGCCCAGGAGGACAGTGCAGGCTCCAGGACTAGGTGTGCTCG +GTTCCAGTCCTGACCATCAGCCACTTATACCTGCTGTGCAACCTTGGGGAAGTCACTTAA +TCTCTCTATGGCTCAGTTTCCTCATCTGTAATATCAAAAACAATAGCATCTGCTTCTGAG +GTACTATTGTCTCGCTGGGCTTATAAATGTTAATTATTATTATAACACATGCTTTAATTG +AAACATGAATTAGCATCTACTGTATATTATACTTTCACATATGCATAGAAAATATGCAAA +CAGGAGGGGAAATATAAGCATATCACGTTGAAGCTTTCAAATTTCACATTGAAGCTTTCA +AATTTCAGCATTATTTTGGTTTTTAGCTCCACCCCTATAGTCTACAGCAATGCCTGGCAC +ATAGTTAGCACTCAATAAATACTTTTGAGTGAAAGAATGAATGAATAAATGAATAAACAA +TTTTGATAACTAAAATTGGGAATATGGGCATGAAACAGAGAAAAGTTCATTAAAGTGTTT +CAAATTCTAATCAAAAGATATTCTTTTTCTGACACGAGGAAAGAGATCATTTCTTTTCCC +ATTAAGTGGTGGAAGTTTTCAGCAAAAGGGAATTGTCTAGCAGGACTTTAATGAGCCCAA +ACCAAATAAATATCTACAGGGGCACATGAAGAAACACACATTTAAAAAGGAGAAATTTTC +TTTGGAAATAAAGGCAAAATTAATTAGCACTTCCTCTTAAATATACCAAAAATATGAGAC +AAATGTGTCTACTGAATATTATAGTATGCTTTTAATAACACTAAAATTTTATGTTTAACC +CTGGCACTGACTGCAATGAGAAGGTTCTTTTAAAGTTTCCCTCAAAATGCTAAAGGCATG +AGTCAATACTTTCACATAGGCATAGAACATATGCAAACAGAGGGGAAATATAAGCATATC +ACCTGAGGGAAAAGCAGGCTGCCCCAGAGGGCCTCCCAGGACAGCACTCATGACCACGTC +CTCCTTGGCCTTGCTACCACCACACCTCATTCTCAGGACATCAAGAGCAGCTCTCTCTCT +CTCTTCTCTATTTCCTTATACATCTCCCTCCCCTCAATCAAGGCATAAGGCAAATATCTA +AATCCCAAGTGCTGATTTATCAACTGACTATGTAAAATAAAAACTGTTGCTGAGTCTAAC +ACATTCAGGTTGGCAAAACTGCTGCATTTTCTCCTTCTATATCCATAATTACATTAAGGA +GTAAAATCACCGGCATAAGTTTGCCAGGTAAAATGGACCTAGAACAAACAGTGAGTGGGA +TTAAGGACTAACCACCTACTTCATAGCACTTAGCAAAAGGAGCCTACTGTATCCACCTCC +ATGGGAGAAAAGGACTTATTGCTGGAATTGTAACACTCAAATCTACAGCCTAAGCTCCCT +TTCCTTGGGTAGTTCTTGAGGGAACGTGGCCAATATTTGCCTCTGTGACTCACATAATCT +AAAAGATGTAGGTTTTCTTTATATGTGTCAACACATTAAATCAGAACACAATCAGGACTT +CTTGGCCTTGAAATTATTTTTTTAAATGCCTTTACCTAACCTGTGATTTGCAAGAATTAC +AAAGTTTAACTTTCAAAAGATAATCTCATTTCTTTCATTTCCAAATTTTAATCAAAAACC +TTACTTTAACCCCTACATACTGATGGGCAATTAAATATTCATAAAAACTTAATATTTATT +AAAAACAAGACTGAAAATGGTACAGCATAATCTTAATTATATTTTTTAAACAAAATGGAC +AAAGTGACTGTGAAAGGAGCTAGAAAACAGTTGCAAAACATAATTTGTTGCTGATGAATT +AATAAGACAGCACACACTGAGCCATATCTAGGTATGGCTTTAAGGTATAGAAAGGTATTC +TTTAAAGGTATAGAAAAGTCTAGTGATATGTACTGAAGAAACATCATCCTCAATAGCCCT +TACTTTTATATCTTACACTGATGTTTGCATCACATCGAACATTTTATAACCAGTACTGAT +AAGGCTCTTCCATTCTTAACTTATCCCAAGTCCCCACTCTTCCCCTACTCCACTCTAAGA +TTTTAAGCTTCATTCTAATAAAAGCCATGCGTTCTTTATGGTTATGCCCATGGAACCTGT +CCACAGTAGACACTCTAAATGTTAGCAGAATGGGTGATGTGACTGGCTCTGTATTCAGTT +ACTTATAGCACTTTTTAACTGAATGCCAACGATACACAATCACCTATCATTGGTTACTTG +ATTTTTTAAGCATAATTTTAGCTTTAAATAGTTCAACATTTAGAGTTTATATATCCCTAT +AATTTACTCTGACTTCCAGGGGTAAGTGTCACCAAGATAGGAGCTTTAAGTACCTGTTTG +CTTACTTAAAAAGGCAAGCAGCTAGACTACCATGAGTGATTGCTTAAGAAAATAATCTGC +ATCCATAGGAACAGAGATGAAGACTACTATATCATCCTTCCTGCTTATACTCTAAAGACT +TTCCTCCACCTTAGTTTCCTCCAACAACTAATCAGATAATCAAAGAGTCTGCCTGGGAAA +GAGAAAGGTTTCCTCAACATCACAAAGTCTCTTTCTATAAGGCATGGTTTGAGCTAACAT +CTTTTTAATGTGCTTTTTTTAGCTTAATATTCTTTTCCCTTTTTCAAACCATGAAGTTGC +CTTGTGTACATAAAGAATATAACAAGTGTAAAGAAAGAATAAAATCATAAAAACTATAAG +CTAGTAAAACAAGTATTAAAAAGTGCAGAGTAGTGGCAGATTTTACCTTATGTATATTTT +ACCACAACAACAAAAAAAAAGGTAGAGTAACCAATAGAAGATGGAAGACTAACATCAGGA +GGCAGTACATATGCAGTCTGTTACAATTGTGTAATGAAACCCAGGTGAAGAATTCCAACA +TCCTTACAAAAGTACCAAAGAAACAAAAGCATCAAAACAAACAAAGTCAGACATTAAAAG +GGAGGAATTTTGCATGCCATGGTAAAGCTGCTTCTTTTTACCAAAGAAAAAAGTAAAAAA +GAAATGTCAAAATCATTTCCATATCCCTTGAACCACAGTGTCAAATACTTCTTTTAATTT +ATCAACTACCCATGGTATACAAGAAACCCTCCCTTGAAATTAGGAATGCACTAGAGAAAA +AGATACTCTAAACGCAAGAAAATTATGTACTGGACAAACACGATCATCCAACGTAGCATG +GTAATCTAATCTCAGCACACTTTTCTTATACAACTGCTGGACTGCAGTGATGGTTCAAAC +TCTCCTTACCTAAAGGAATGTGAAAAGGCTTGCAATCTGTAAGAAGCCAGAGTAAGCATT +AAAAAAGAAAGAAGTTCTGATAAATCTAAAACAATTAAATAACCTAAGTTTTAAACATAT +AATGTTTTCCCTGGGCTCTAAACTGCTACACAATTCAGTCAGCATAGAGAAAATGAACAC +CTAATAGATACATACATAATTGTCAAAAGAGTTCAAGAAAGCTATATTTATTACATTATG +CTTAGACAATGACAGTCTAAATATAATGAGCGAGGAATTTGTTCTTTTGGTGTAAAGTAT +AACACATAAATTGACCAAATCTATTCAACCAAGAAATTCTGGTTGTAAGATATACACTTT +CCCCACAAATGCAAAACACGAAGCCATGCAATCTGAGCATTTTTTTTTAAACACAAATCT +TGCATGCCAACAGAAGCACAGCTGACTTAAACCACATTTGTCATTTTCATCACTATCCTA +ATCCACATGAGTGAAGGGGGGGCACAAAAGCACTGTGAAGTGGTTTTATAAAAATGGCAA +GGAAAACTCTGCAGACTAATCTAAATGAAAAAAAAAAAAAGCAACAACTCAAAATCAAGA +TTTTGGCCTAAGCATGAACATAGTTACAGCTTACCAGTTAGAATAAAACAGTGCACAAAT +GAGCATGTTGTAATCACACCATGATATAAAATGTCACATATAGAACGTGAAGCCAAATCT +GAATCGAAGCGTGCACTTCAGTGCTCCTGTAGTCATCCTTAGTAACACACCAGGCTCTGC +CCACAATCACAAATTTGCAACCAAAGACATACTTACCCTGCATGATCATGAAGAACTAAA +AAGACAAAGAAGTTCACAACCAGAATTTTTCAACAACCTTAAATGATCATCAGATGATCA +TTTGATGTTAGAATGCTAGGCCTAGAAGACCTTAGATGAGCCTTCCAGGTACTGGTTTGA +AGGAGTGCCCTCCCTCACTCTAACAGGAGTAGCTAGCATCAACTAGAGCCAAGGTCAGGA +AACAGATGCAACAACAATAACATTTTAATTTGCGTCAGCTACTTAATGAGCAAGGAAAAA +TGAGGACATACTTTACATCTTCCAGCTTTTTGGTGATGACTGAGCCAACAGACGAAAAAG +CAGCTGAGGCCTTCTGTCCAGCCTGGGATAAGGTTTCAGATGTCTTCTTGTAACTATATT +AAATTATAAACACACAGAGCAAAAGAAGGGTCAGCTCATCTTTTCTAATATCAATTGTTT +CAAGTGCAGTGGTCACCACCTGCTGGAGAACTCTCAAAAAGAGAAAACATTTTTCAGAAC +TTCTAAAATCCTTCATAACCAGCAGAGCGGCATCACCACATCTTCGTATGCTCAACCCTA +AGCTCAGGCACAATCTTCTGCAGTGCCCTAGTCCAGCCAGAAAGACAGAGTCCTATAAAG +GCAGGGCCAAAGAAGTCAAGGTAAGGGCTAAAAATAATCATCAAACCAAGATGAAAATAA +GCAAAGGCCTGAAAGAACTCATACCTATTGTTCTTTTCTCACATAATCCAAACAAAACAA +AAATGAAATCAAATTCCTCAGATGCCTTTGTCAACTTGATTTCCTAAAAAAGGGCCAGAA +GCAATTAGTAGCTGGCGTAAGTAGGACCCATTTGTATTTTATTATCCAAATACATTTTAT +GGGCATACTTTCTAAAAATTTTTGCATGTCTTTAGAGAGCTACCAAATACGGACATGATG +GACTTTCAACAAAGTATGTAAAATATGCAATGCTTAAAATTATTCTAGTGTGGTATCTGC +TATCACGCAAAGCTATAATTTACCACCTCCTTCCCAGCTACCTGGAGATTAGAGAAGAGA +AAAGCAAAAACAAAAAAATGATGACAACAACAACAACAAAAAACAAAATAATATCGTACC +TACCAAAACAATTCCCACATTATGGGAAAGAATGCTCAGGCATTTTTACTTACCCTGTCA +AGATCAAATACCAATAAAAAAACATGGTTCATGGTAATACTGTTGAAAAAATAGTTTCCT +GTATGTTTTCCCACTGCCAACTTAGATGGGTAGAAAATGGACCAAAAGACTGGGGACTCA +AGTACTGTCATGTTAAATGCAGTTGGCCTCACTTCTGATAGTTAAATTGTAAAACAACTT +CTGTGCTCACCAGCTCTGCAGATGGCTCTCAATACAGAAGACAGAGCAGTTCGGTTTCTG +CTGCTAGAAGCTTGCTCCTCCTTGTGCCGGGAAACAAAACTGCATTATGATAATGCTATA +TCATAGCATGTGTGGTCAAAAAGACAAAAAGCCTAAGGGATTGACCTCTGCCAAGAGCAT +ATATCTGAGACTACGACCTGAGAATCTTTTGATACCTACACAACAAGGTTAAAAAAATAC +ATTAATAATAATAATAAAGACTGGCTCCAGACCTGAGTTTGAATTCCCACTCCACATTTT +GAGAGGTTTGTGACATGAAAACTTAATTTGTCTGAGCCTGTTTCCTTATCCAGGGTTATC +TTGCCACCCATTCTTACTGGGTTATTCTGAGTACTAAAGGACAAAATGTACATATTTGTG +GCAAGTCAATACATAACACTTATGGGATTTGAATTTTATTTCTCCAACTGGCTAGCTTTC +TTTCTATTCCTTAGAATAAGTGGTCTGGAAAAATTGAAGTTACAAAAAAAGGCAGGCACA +CTTGAAAATCAGAAAAAAAGGGTGCCGTGTCGTCCAAAGAAAAGCTGCTGAAGCATCCTT +ATCCTCTTTTTCTTCCCCTCTCCAGACAAAAGGCACAACAGTGTCCTTTACACTCCCAAG +GAAAGTGTATGATCAAGGAAACATACGCAGATGTTGCTGTCACGTCTTGCCACCCTTTGG +CAATGTTCTGTTTTAGTTCCTGTAGAGAATTGATTCCAAGTTTCCGCTTGATCTCTGCTA +GATGCTTCTCTTTTGCTGCTAACACTTGAGACAGAGTCTGGATTTCTTCTTCTACCTATG +AGGAAGGGGTTTGGGGTAAGAATATAGCAAAAGTCATTCAGTAAGTTAAGATTATTACCA +CAGAACTACATCCAAAATTCCAGTCATTAAACATTTTTTTGAATCATTTATCTTTCTCTC +TAAAAACAATGTATAATGTTGTTGAGTAAACTGGTTACTTGCTGATCTCTCCTGTAGAGT +TCTCTTTCCTCCTCCATGGGAGCTCTTTATAATCCCATCTTAAGCTGTTTTTGGCCTTCT +CCTCTCTCCCTATACTTCCTTACTCAGCTATCTCATGTAGGTTTAGGACTCAAATTTCTA +CACAGATAATACTTAATAAAGCACTCTAACATCCACTCTCCCGACCTGTGGGTCTGCCTT +CCCAGCCTAGACATTTCTATCTGAATGCCTACAAAACTTGTATTTGTATACTAAATCAAA +ATAATCTCCATCCCCTACCAAAACACACACAACCAAGCCAAACCCAAATCCAATCTCCTT +GCATATTTGATATGAGTATATATACTGGATACATATACTCAGTCCCTGTGTCTGGCAAAG +TCATGGCCATAATAAATCAAACCGCCTCCTCAGGAGATCCCTGCTCTCAAGGGTTTCATG +TGAACCCCTTGATGCTGACTGCCCAGACTTGACTAGGTGGTTAGAGGTGGGCCCTGACCC +ATGGACAGCCACCCATCAAGAGCCAGTGGATGAGCCCAGTGTGAAAAGAGGTGCTCAACT +ATTCGTCTCTCTCACTCAGGAATCTAGTTTGAGAAGTGAGATGACATTGCAAGTAGAAGC +TGAAAAAACTTGAAGAAGCCTTGAGGTATAGGTAGGCTACAGTGAGATTATGAGAGGTAT +GGAAAGCTTAAATATGCTTGAGGAATCTAAAACTGTAAGCAGAAGCTATGAAGAAAAGGA +AAAAATGGACAGAGTAGAACAAAAGGCTAATCCAGGAAAACAGGGAAAATGGTAGACTCT +CTATTTCAGAAACAGGGAAAAGGGTGGACTGCCTATTTCAGAGAGAAATAGACACCATGT +GGAAGAGACTTTAGGTCCCAGGAAATTGAAAATCTAGGTCCCTAAAGTATATCCATTAAC +ATTCAAGACCCTCAGAGAAATGCGTCTCCTGGCTTGTTGCAAAGCCATATTTTCAGCCCC +AACCTGCACGGTATTTCTATGATTTCAAAGACAACATGCCCTTTAAAAATAACATAGAGT +ATTGCTCAGTCAAATGTTTTCACAGATGTTTAAGTCTTTAGAGAACACAAAACAAAGAAA +ATTAGTGCAACGGAGAAAAGGATAAATCAAATGTGATGCAGCTGCCAAGAAAAAAAAAAA +AAGAAGAAAAAGAACCTACAACACCACTCTCAGATAAGATTAACTGGAACAGAGGTCCCT +CAGAACAAATAAATAATCCCCTGTGCTTGTCAGAGTCACAAGTACTGGACCCAGTTTTGT +AAGTCACATTTTAAGATGTACATTGACGAAGTGGAATACGAGAAGAAAAGGACAAAAAAA +GAGGAAAGAATAAGGTTCAAAATTAAGTAAATTAAATGATTTGCCCAAAGTCATCAAACA +AATAATGTAGGAACCAGAATTCCTATCTAGGTTTTCTGAATGCACGTCTCAGTTTACTGG +CTGAATTCTCATGTACACTCTCTTAAGCTTCCCACTTCCTCTGTCTCTACTTCAGGCTCC +AAAGCTTCAGACACTTCTAAGAATAGACTTAAATGGTAAGTTTCCCACCCCTTAGCACTT +CTCTGAGGTACTCACTTCCTCTAATGAAAGCTGCAAAGACAAACCACTCTAAATCTTTCT +GAACAATGCACAACACAGTATATTCCCCACCTTTGTTGGTTAGCTTGTGCTGCTAACACA +CCTAGCCCAGCACATCATGGCTGCGATTCCTTAATTCAATATATACATGTAAAACAGAGT +GACTTTAAAAGCATAAAGAGCATGATTAAGAATCTCTGATGTGTCTATCACTATATACAA +AGATCAACTCAAAATGGACTAAGGACCCAAAACCATAAAACTACTAGAAGAAAACATAGG +AGAAACACTTCAGGGCATTGGTCTAGACAAAGATTTTATGGCTAAGACCTCAGAAACACA +GGCAACAAAAACAAAAATAGACAAATGGGACTAAATTCAAGGAAATCATCAACAGAGTGA +AGAGATAACCTGTAGAATGGGAGAGAACATTTGCAAACTATTCATCTGACAAGGGACTAA +TATCCAAAATATACAAGGAACTCAATTCAACAACAAAACAAACAAGCAATCCCATTTAAA +AAGTGGGCAAAGGATCTAAATAGACATTTCTCAGAAGAGACATATAAATGGCCAACAAAT +ATATTAAAAATGCTCAACATCACTAATCATCAGGGAAATGCAAATCAAAATCAAAATGAG +GTATCACCTCACACCTGTTATTATGCCTGTTATCAAAAAACCAAAAAATAACAGATGCTG +GCAAGGATCCAGAGAAGATGAAACTCTTATACACTGTTGCTGGGAATATAAATTAGTACA +GCCACTATGAAAAACAGTATGGAGGTTTCTCAGAAAAACTTAAAATAGAAATACCACATA +ATCCAGCAATCCCACTACTGGGTTACTTATCCAAAGGAAAGGAAATCAGTGTATCAAAGG +GTACCTACACCCCCACGTTTATTGCAGCACTATTTACAATACCCAAGTGTCCATCAACAG +GTGAATGGATAAAGAAAATGTGGTATACACAATGGAATACAATTCTGCCATAAAAAAGAA +TGAAATCCTGTAATTTGCAGCAACATGGATGAGCCTAGAGAACAATACGTTAAGCAGAAT +AAATCAGGCACAGAAAGATAAATACTGCATGTTCTTACTCACATGTGGACGCCAAGAAAA +AACTCTGAACCCATCTAAGTAGAGAGTAAAATTGTGGGTGTTAGAGGTTGGGAAAGGGAG +GATGCCTACAGGTTGTGCTTCAAACGACACTGTCATGAAAGTAAAAGACAACCAACAGAA +TGGGGAAAATATTGGCAAATTACATACCTAATAAGAGTCTAGTATCTAGAACATATAAAG +AAACTTACAACTCAATAAAAAGACAATCCAATTAGAAAATGGGCAAAGGACTTAAATAGA +CATTTCTCCCAAGATATACAAATGACCAATAAGCACATGAAAAGATGCTTAACACCATTC +ATTAGTAATTTGAGAAATGCAAATCAAAACCACAAGGAGATACCACTTCATACCCATTAG +GATGGTTACAATTAAAAAAAACAGAGATTAATAAGTGTTGGCAAGGATGTGGAGAAATTG +GAACCCTCAGACACAGCTGGTGAGAATGTAAAATGAAGTTGGGCAGCAAAGCAGTTTGAC +AGCTCCTCAAAAAGTTAAACATAGAGCTACCATATGACCCAGCAACTCCACTCCTAGGTA +TATATAACAAAGAGAATTGAAAACACATCCAGGCTGGGTGCAATGGCTCACGGCTGTAAT +CCCAGCACTTTGGGAGGCCAAGGTGGACAGATCACTTGAGGTCAGGGGTTTGAGACCAGC +CTGGCTAACATGGTGAAACCCCATACTACTAAAACACAAAAATTAGCCAGGCATGGTGGT +GGTGTGCCTATAATCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATCACTTCAACCTAGG +AGGCAGAGGTTGCAGTGAGCTGAGATCATGCTACTACACTCCAGCCTGGGCAACAGAGCA +AGACTCTTCTCAAAAAACAAACAAGCAACAATAAAAAGAAAACACACATCCATACAAAAA +GCTGTACACAATTGCTTACAGCGGCATTATTCATAACAGTCCTAAAGTTCAGCCACTGTG +GAACACAATTTGGATACTTCTCAAAGAACTTAATACAGAGCTACCATTCAATGGCAGCAA +TCCCATTACTGGGTATAGAAATTGTTCTACCAAAAAAACACCTGCACTCATATGTTTATT +GCATCACTATTCACAATAGCAAAGACATGAAACCAACCCCGGTGCCCACTGTCCAATGTG +GTACATATACATCATGGAATACTATGCAGCCCCTAAAAAGTACAAAATCATGTCCTTTGC +TGCAACATGGATACAGCTGGAGGCCATCTTCCTAATCAAATTAACACAAAAATGGAAAAC +CAAATACCACATGTTCTGACTTATAAGTGGGAGCTAAACATTGGGTATACACAGACACAA +AGATGGGAACACTAAACACTGGGGATTCCAGAAGTGGAGAGGGAGAGTTGGGGGAAAGAG +CTGAAAAACCATGTTCACTACTTGGGCAACAGGATCATTAGAAGCCCAAACCTCAACATC +ATGAGGCATTACCATGTAACAAACCCGCACATGTACCCCCTGAATCTAAAATTTTTTAAA +TAAAAAATTTAAGTTTAAAAATGTTTTAAAAGGGACTATAAAGAAAATGAAAAGGAAAAT +CCACAGAATGGGAGAAAATATTTACAAATCATATAGCTGGTAACTTCATTTGTTAAATAA +AGACTATGTTTCCTCTTCCATCAATCATAATAGCACCTGCCCCGTAAGACTGTTGTAATA +ATTAATGAAATAATGCATGTAAAGAGCTCAGTTTAACGCCTCCCACACAGCATGTAGTCT +ATAGACATTAGGTGCTATTACTATTATTTTTATTTTGTTGATAATAAAACAATACTGAGA +ACTGTCAAGGATTTGAAAAAAAATGCTCTTTCAAAACACTGTAAGAAATATGCTGGATAG +CATTTTGGCCATGTTGCTATATACTCTTAAAAACCATTAGACCCAGGCATAATGCTACTT +CCAGGACTTTATCCTAAAGCGCTAATTAAAGAAGTGCATAAAAACTTACATGAAGGTATT +TTCATCAAACTATTATTCATAATAGCAAAAAATGGAAACAATCCAAATGTTTATAAATAA +TATAAATTAAAAATGAGCTTGCGGAAATTCAAAATGGACTACGCAGCAATTTAAAATGAG +GTTGCACAAGAGTATATTGGCATAAAAATGTTTTTGAAAATCAGTTAAGTGGGAAAAGGT +TATCTGTATTCTAATGCCCTCTACAAATATAAAAATATATGGCTGGGCATGGTGGCCCAT +GCCTGTAATCCCAGGACTTTGGGAGGCCAAGGCAGGTGGATCACCTGAGTTCAGGAGTTC +AAGACCAGCCTGGCCTACATGACAAAACCCCATCTCTGCTAAAAATACAGAAATTAGCTG +GGCATGGTGGCACACGCCTGTAGTCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATCGCT +TGAACCTGGGAGGCAGAGGTTGCAGTGAGTCAAGATTATGCCACCACACTCCAGCCTGGG +CAACAACAGAGTGAAACTCTGTCTCAAAAAACAAAACAAAACAAAAAAACAACCACACAA +ATGGTTTATCACCCATCTGCCTTACCCATTCTATCCCCACCTTGTTTATAAAACTTTGGG +CGAAAAAATGAGTAGTACAAACAGACAGAAGATCATAGAGACGACTTGAACAATACCATA +CATCAACTGGACCTAACACATATATGTACAGAACAGCTCACCCCAAATTAGTAGAAATAC +ACTGTTCTCAAATGCACATGAAACATTCTCCAGGACAGAGTATACGTTAGGCAACAAAAC +AAGTCTCAATAAACTTAAAGTCATACAAAGCACCTTTTCCAACCACCACCATGAAACTGG +AAATCAAAAACAAGAGGAAAACCAGAAAATTCACAACTATGTAATAATCAAACCACACAC +TTTTAAACAACCAATGGGCCAAAAAAGAAGTCACAAAGGAAATTAGAAAACACCTTGAAA +TGAAGGAAAACAAAAACAGTGTATTAAAACTTTTGGGATGCAGTTGAAGAACTGTCAGTA +AGAAATGTATAGTTATAAATGCCTACATTAAAAAAAATCTCAATAACCTAACTCTACACC +TTAAGGAATTAGAGAAAAATTTAAAAAATAGAAAACTACACCCAAAGCTAAGAGAAGGAA +GGGAATAAGGAAGAGATTAGATATTAGAGTAAAGATAAAATGGACAAGAGGAAACAATAG +AGAGAATGAATAAAAGCAATAATTCATTCTTTAAAAAGATCAACAGTGCATTAAGGGTTA +AAAAAAAGAAAAAGACAGCCAGGCGCAGTGGCTCACGCCTGTAATCCCAGCACTTTGGGA +GGCCAAGGCGGGCAGATCACCTGAGGTGAGGAGTTGGAGACCAGTCATGCCAACACACTG +AAACCCCGTCTCTACCAAAAATACAAAAATTAGCTGGGAGTGGTGGCACGTGCCTGTAAT +CCCAGCTATTCAGGAGGCTGAGGCAGGAGAATCGCTTGAACCTGGGAGGCAGAGGTTGCA +GTGAGACGAGATCGCACCATTGCACTCCAGCCTGGGCAACGGAGTGAGGCTCCATCTCAA +AACAAACAAAAAAAAAGAAGTTCAAGACCAGCCTGGCCAACATGGTGAAACCTCGTCTCT +ACTAAAAATACAAAAATTAGTCAGGCGTGGTGGTGCACGCCTGTAGTCCCAGCTACCAGG +GAGGCTGAGGTACAAGAATTGCTTGAACCCTGGAGGCAGAGGCTGCAGTGTGCCAAGACT +GCTGCCACTGCACTCCAGCCACCTGGGTGACAGAGCAAGACTCCATCTCAAAAAAAAAAA +AGAAAAGAAAAAGATGAGTGAAATTGACAAACCTATAGCTAGACTGACCGAAAAAAAAAA +AAGAGAGAGAAGGCATAAATAACTAAAATCAAATGAAAGTGGGGACATTAACTAACCTTA +TAGAAACAGAAAGGATTATAAAAGAATATTATGAGCAATTGTACACCAACATACTAGATA +GTCTAGAGTAAATGGACAAATGCATAGAAATATACAAATGACTAAACTGACCCAACAAAA +TAGAAGAAATCTGAACAAGTAAAGAGATTGAACAAGTATCAAAAATCTCCCAAAGAAAAG +TGTAAAAGTAGATAGCTTCAATGGTTAATTCTACCAAACATTTAAAGAATGGACAAACCT +TTTCAAACTCTTCTAAAAAACCAGAAGATGGTAGAACACTTTCCAACTCATCTAAGAAGC +CAGCATTACCCTATTTACCAAAGCCAGAGAATGATATCACAAGAAAACAGCAGCCCATAT +CTCCTATGAATATCCAGCAGCATATTAAAAGGATTATAAAACATGACCAAGTGGAATATA +TCCTAGGAATGCAAGGATGATTCAACACATGAAAATCAACCAGTGTTATATACCACATTA +ATATAGTAAAGGGGAAAAACACAATCATTTCAATAGGTGAAAAAAAAAGCATTTCATAAA +AATCCAATACTCTTTCATGAAAAAAAAAACCCACTAAAACTAGGAATAAAAGAGAACTTC +CTCAACGCAAGTGCATTTGTGAAAAAAATGACAGCTAATATCATACTTATGGTTAAAGAC +TGAAAGCTTTCCCCATAAGATCAGAAAAAAAGACAGGGATACCCATTTTTACCATTTTTA +CACAATATTGTACTGAAGAGTTTAGCCAAAGCAGTTAGACAAGAAAAATAAATTAAAGGC +ATTCAAATTGGAAAGGAAAAGTAAAACGATGTTTAATCACAGATGACATGATTTCATATA +TAGAAAATCCTAAAGAATCCACAAAAAAGGCCAGGTGCGGTGGCTCATGCCTGTAATCCC +AGCACTTTGGGAGGCCGAGGCAGGCAGAACACCTGAGGTTGGGAGTTCACAACCAGCTGA +CCAATATGGAGAAACCCCATCTCTACTAAAAATACAAAATTAGCCGGGCGTAGTGGCACA +TTCGTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGACAATCGCTTGAACCTGGGAGGT +GGAGGTTGCAGTGAGCCAAGATCATGCCATTGCATTCCAGCCTGGGCAACAAGAGTGAAA +CTCCATACCTTCCCCCCCACCGCCCCCCCCAAAAAAAAAAGAATCCACAAAAAAATCTAT +TCAAGAGTGGTTGTGGTGGCTTATGCCTGTAATCCCAGCACTTTGAGAGGCCTTGGCAGG +AGGATCACTTGAGTCCAGAAACATAGCAAGACCCCACCTCTACTGAAAAATAAAAAAATT +AACCAGGCAGATGGTGGCAAGCGCCTGTAGTCCTAGCTACTCAGGAGGCTGAGGCAGGAG +GATCACTTGAGCTGGGAGGTCAAGGCTGCCCCGAGCCATGATCACATCACTGCACTCTAG +CATGGGTGACAGAGCAATACCTGTCTCAAAAAAATTTTTTTAAATATATTTGAGCTCATA +AATTCAACAAAGCTGCAAAATATAAGATCAAGATATAATATTCAGTTATGTTTCTACATA +ATAGCAATAAACCACCTGAAAAGAAAATTTAAAAAAAATCCATTTACAATCACATCAACA +AGAATAAAACACTTAGGAATAAATATAACTAAGGAAGTATAAGACTCGTACATAGAAAAA +TGTTTTGTACATTGCTAAAGTAAAATAAGAACTAAATAAATGGAAAGACATTTCATGTTC +ATGGACTGGAAGACTTAATATTGTTAAGATGGCAATACTCACCAAGTCAATCTATAAACT +GAACGCGAGCCCTATCAAAATGCCAACAGCATTTTTGTGTGGGTGGAAAAGCAGATTCTG +AAATTCATATGGAATTGCAAGGAACCTTGAATAACAATTTTTAAAAAGAAGAAAAAGGTA +AAGAACGCATATTTCTGGATTTCAAACTTACTACAAAGCTATAGTAATCAAAATAGTGTG +ATACTGTCAAAAGAAAAGACATATAGATGAATGAATCTGAATCCAGAGTCCAGAAATAAA +CCTATACATCTATGGTTAACTGATTTTTTTTCTTTTTTAACAAGGATGCCACGAGCATTC +ACTGGGGAAAACTAGCCACATGCAAAAGAATGAAGTTAGATCCCTACCAAAACCATATAC +GCTAATTAACTCAAAATGGATCAAGGGCTTAAATCTTAAGAGCCAACACTATAAAAGTCT +TAGACAAAAACATAGGGGTAAATCTTTATCATCTAGGATTTAGAAATGGATTCTTAGATA +TCACACCAAAAGCACAAACCAAAACCATAATGAGATATCACTTCACACCCACTAGGACTA +CTATAATCAACAACACAGAAAATAACAAATGTTGCCAGGGATGTGGGGAAATTGCTGATG +GGAATATTAAATGGTGTTAATACTGTGAAAACAGTTTGGTGCTTCCCAAAAAAACTTGAA +ACATGGGCCAGGAACAGTGGCTCACATCTGTAATCCCAGCACTTTGGGAGGCTGAGGTGG +GAGGATCACGTGAGGCCAGGAGTTTGAAACCAGCTTGGGCAACATAGCAAAATCTCATCT +CTATGAAAAATAAAAATTAAAAAATTTGCCAGGCATAATGGCATGTACCTGGAGTCCCAG +CTACTCAGGAGGCTGAGGCAGGAGGATTGCTTGGCCCAGGAGTTCAACATTATAGTGAGC +TATAATCATGCCACTGCACAATCACCAACCCACAAAATAGAGCAAGACCTTGTATCTTAA +AAAAAAAGTTAAAAAAATTTTAAAACATTAAACATGGAACTACCACATGATGAAGCAATT +CCATATCTAGGCATATATGAAAAAGAACTGAAACTAGGTACTCAAGCAAGTATTTGTTCA +TAAAATGTTCCTAACTCACTACCCACCATAGTCAAAAGGTGAAAAATCACCCAAATGTCT +ATGAATGGATAAATGGATAAACAAAATACAATAGATACATGTAATGGAATATTATTCAGT +CATTAAACATAATGAAGCACAGATATGTGCTACACCATGAATCAACCTCAAAAACATGAA +GGGAAAGAACCCAAATACATAAGGTTACATATTGTATGATTCCATTTATATGAAATAACC +AGAAGACAGTTAAATCCATAGAGTCACAAAGCAAATTAGGTATTGCCAGGGGCTGAAGGA +GGGGAGTAGTCAGGATTGAATGCTTAATGAATACAGGGATCTCTTTGGAGGTGAAGAAAA +TGTGTGGAACTTGAAAGGGGTGGCAGCTGCACAACACTGTGAATGTTACATGTTACTGAA +TTATACTCGTTAATTTTTTTGCCTGTAATCCCAGCACTTTGGGAGACCAAGGCAGGTGGA +TCACTTAAGGTCAGGAGTTCGAAACCAGCCTGGCCAACATGGCGAAATCCATCTCTACTA +AAAATACAAAAATTAGCTGAGCACAGTGGCAGACGCCTGTAATCCCAGCTACTCAGGAGG +CTGAGGCAGGAGAATCACTTGAACCCAGGAGCCAGAGGTTGCAATGAGCCAAGATTGTGC +CACTGCACTCCAGCCTGGGCAACAGAGCGAGACTCCATCTCGAAAAATAAAATATAATAA +AATGGTTAATTTTTATGTTAAATGAATTTCATGGAAGAAGTTAGGAAAGAAAAAAGTAAG +AAGGGAGGGAAAGGAGAGGAGGAATGGGGGGGAATGGCAGAGGGAGGGAGGGGGAGGGGG +GGCGGAAAGAGAAAAAAGAGAAGCCAGAAGGGGAAGAAGGAGGGGAGGGAGGGAGGGGAA +GGAAGAAAGAGAGGGGAAGGAAGGAAGGGAGAGAGGGGAGGGAAGGCAGGGTAGGGAAGG +GAAGGGAGGGGAGGGAAGGAGGGAGCTGGAAGGAAGGAAAGGCGGAAGGAAGTTGGAAAG +TGGCCATCTCTGCAACACAGCCAAGGGTAGAACAAAGTCACTGATGCACTGAAGAGCAAG +TGTATCAGATGTCAGTGAAGTCCCTTAGAAGACATTCACTACTACTCCTCTCATTCATTT +CCTGCTTCACACTCTACTTTTCACATCTATTTTACCCATATATACTTTTTTCTCATATAA +AAACGAACCGATGTCACCCTCTTCTATCTCCTCTCCCCTACTCAAGACCTGCTGGAGAAG +TAAACACATATGCTTTCTCTCCCCTGGAACTAACTATAAACATATCACCATGTACTTTAG +AATCACAAATGACAGTACATTTTAAGTGCAAAAATAAAGTTGCAAAAGGAATGGTTCTTT +ACCTTTGCAAGTTCTCTTCTTAGCTCTTCCTGCTCCTCTTCCGAGAGGGTCTCTGTGGCA +CTGATCGTGGCAGCAACATCTTCTCCTTCCTCAGGGACTGGGTCTGTTCTCAGCAGACCT +GGTTGGGGATTTAAACCATTTTTTAAAGTGCAAAATCTAAGTAAAATCCCTATTTAAGCT +CCTCCACTGTCCTAGCCAGAATAAAGCCAATTAGAGTAGATCCACACATCTCATCTCTGG +ATATTCAAATGACCTGGCTTTCTCAGCAAAGGACAAAAGAAAATCTGAGCTAACCACCGG +AAACTACCAAGTAGACTCTGCCAAAATATGAATTTAGAAAATATAGCATTCTCTTAGCTT +CTGTTCATAGTCTCAGTCACAATATAGTTATGGCAGAAGAGTGAAGGGCCCAAAATGAGA +TCTTGCTGAGACTTTAAATTGCTGCAAAAGTAAATCAGTATAAATTAGATGAAAGATTTT +AGCTCCTTCCCAGTAACCCAGGGCAGGAGTTTGCATATCTCTTCAGCTTGCTGTGGTAAT +CAAAGCCAACATTTCATAAACTCAGTAAAGGAGTAACCACTGAATGAACTAAATGTCCTA +AGTAAATTTTATTCTGTTTCTTTCCATTAGTGGAGGCAGAAAACATCTTCTTGTAAGTTC +TTTTTTTGTTGTTTGTTTGTTTGTTTTAGGAGGTAGAGACAGGGTGTCGCTATGTTGCCC +AAGCTGGTCTTGAACTCCTGGCTTCAAGCCATCATATATATATATGATGATATAGATGAT +TATATCTATCTATATATATCTATATCTATATATCTATATCTATCTATCTATATATATATA +TATCATCCAGATACCCTTATAAAAGAATACTAAGGTATATGTTCAGAGACATGACCAACA +GCCACACAGAGACATTCTACACTACTGAAGACCAACCACACCGCACCCATTCCCCTTGGA +ACGGAGCCTGTCAGGAAGAACAACTGGAGAGTGACCAGGAGGCAGCTGCCCCTCAGATCT +CCCCTCTTTTCCTGCCCAACCCTCACCCACAGGCTAAGATGAGGCCAGAAAGGCACCCCA +ACCTTGGGTGCAAAATTGAAGAGGCCACTAAAACACTCAATATAAATATCTTAATGCAGT +ATTTTTTAAAAATCAAATTCAAAGAACCCATGATGAACAAAAATGCCAAAATTTTAAATT +GAAGGATCAGTATTGCTGATACTTTGTCTCAAACTCCAAAATGGCTCTGCATGAACAGCA +CTATTGGTAATCTCATCTTTATTTAAAATTGTGATATTTTATTCATGATTTTCTTTTACA +TTAATTTTTAAAAATATTGTATTTGTATATTATTTGACGACTAAGCTTTTTGTCACCCCC +TTCCTGGCCTCAGCTGCCTTACCCTAGGCTTCAGTTCAGTTTACAGATTTGGGATTACAA +AGTCTCCTCTGGCAACAGATTTTTTTTTTTTTTTTTTTGCAAAGAAACCAGGGGAAGGTT +TACTCCTCTGCCTGCTCTTCCTGCCAGTGAGCATCACAGCCACTGCAGTTGTTCCCTGCT +ACCCCCCAGGACCATTTCTGAGAACTGCCAGTTCAGCCACAGCAGCAATGTGGCATCCTG +CCCAATGCAAGGCGCCAGGGAGCAGACACAGAAGAAAAAGGAAGGAGAATAACCACACTG +TGGAACAAGCAGCCAGCGTCGCAGCAAGCATTAGAGAATTACATGAGTCAATGAGATGAT +GCTTATGTACATGGTGTACAAGTTACAAAGGCACTTGGTACAGGCTCTACTGTACACTCA +CTGATTAATAGCAGTTAATAATTATAATAATAATCATCAGCATGGCAGCACCAAAATAGT +GCCTACCTGGAAAGCACAGAACTGTTAAAGGCATAAAAGTAACACAAAAAATTCAAAAAC +CACAAATCGGACTGGCAAAAAATATGATTAAGCTCTTGACTGAATATAAAATATTTAATA +GGTACAATCAGCAAGTAGAAAAGCTCAATGCATAATTGCTTCCGCAGGTCTTCCTCTAAA +ATATTTGTGAACAGACTGCCCAAATAATATTTCTATAATAGAAATCTGACTGTATCACTC +TTCAGCTTAAAATCCTTTGGTGATTCCTTACTGTTTTCAAAGCAAAGTGTGACCCCTGAG +GTTGGCAGGTAGCCCTTACTGGACCCGTCTCCTGCTAGCTGGCATTGGCACCTCTTACTC +CAACTCCTGCCAAACCACACCGTGAACAACGTGCTGTACTATGTACTGTCAGAAACCATT +TCCCAGCATCTGTGTGTGCTTGTAAATCTACCCTCTATGTCAGATTATGTGAAGAAAGTT +GTATGAGATTGAAACTGAGAGTCAAGCATTCAAGTAACAATCATATAAGGCAACACAGTA +AGAACCATAACAGAGCTACCTGTTAAACGTTATTTTATTTTTAATGTTTTGTACAGAACT +CCCAGGTTCTCCAACTACAACAGATCTCCAAAACAAAACAAGCAAAACTCAGGTACCAAA +CCATTACTTAAATAGCAAAGACTCTTTCATGCTTTTTTGATACACACTGTTTTGCAAATC +TACTCAAACAAGGGGAGAAATACAGTATCTGACTGCTAACACAATGCTTTATGTATACTG +CCCAATTCCAAAAAGAATCCAAGGGGATTCTGGTTCTATTCAAGTATGCGGCTAGGCTAT +CAAGGAAAATAAATCTCTCAGAAAAGAGGATGACGGGTTGTCCAGTTGGCTTCAAGTCTG +CCAGGATGACCTTGAGATTTTATATTCAGCATCTAAGAAAGTTGGTAATGACATGTTCTG +CTCTTTCCACATTAGCCCGTAGGTGGCAGCAAATCATTATCATTAAAATTAAAAGGTGCA +GTCTGGAAAAAAAAATTAGAAATTAAAGAACACCAAGGAAGAACAGAATGGTAGATACCA +AAATCACCAGCAAAACATCACAGTCATGCCTTGAGAAAATTATTAACCACAGCCACCATG +ACAGAGTGCATTCCATTTACAGACAAGTCCAAATTAAGTGTTTTAAATACTTATGTGCAA +CACTTCTGTGAGGTGGGGATCCCTGTCACCACTTACAGATCAGGAACCTCAAGCTTACAG +ACATTAAGCAACTTGCCCAGGTTAACACACCTAAATCTTTGGTGGAGGTCAGATTTTAAA +CCTAGACGGTCTGATGTAAAAACAAATGCTTCACATCACTGATCTGAAAACAAAGACAAA +AGTAGGAGGCTGATGGTCAGACCTGAAAGGTATCTAGAAGCAATAATAAGACCCTAAAAA +GTGAAAGAATCTGGCAGACTAGATCAAAAGCAGTCTTCATTAATTCCAACTAAAGTTTCC +CCAAACCTGGGAATCCAAATTTTGCCTTATATATTCGTCTAGATATGATCCTGTTTCTTG +TATGTTCAGTAATGGTATAGGATTTAATATGAAAATAGAGTCTGGCTTTTGGGAGAAAAG +ATTAATTTCTCATTCACAACATGAAAGGTGGAAAATAAGAACATTTAAAAGTATAGATTA +TTGAAAACCATAATCCAAAACTTATTTGTTCATTAATTTTAATGTTGTTTTTTTTTTCTC +AGAATCTGATGGAAAGCTGTTTTTAAAAGACAAAGATGGTGGGGAAAATACAATTAATAT +CTACTGACATCTACTACACCAGCCACTGTGAGGGGAAGTCTACATGTTATCTTATAAAAA +TAAAAACACCCCATAACCACCATCCGAGAGGAGTATTTTTTTTCCACCAGGAAACTGCGG +TCCTCTAAGGCTATATAATTTGCCCAGAGTTACAGAGGCAGGATTAATACTTGGGTCTTT +CTGTCTCTCGACTCAGCTCCATCACGAACATCTTAGAGAAACATCAATGATCATGGCAGG +ACAAGGAAACAGGGCCTAGTCTTTCTCCATAGAAACGTTTTACTTTCCTGAGGGTCTAGG +AACCTGTGGGGATCCCTGGTTTGAAAGTCACAGATAACATTATCAAACACAAGTGACTGA +AAATGAGTGATAATTTCTTCCATCAGGTTATTAACATTTTAGCCATTGCCTTAGTTCTCT +TCATCTAGCTGTGCAAACAGATTGTCAGCCTGTCTTCAGTTCCATCCATAGGATCCCTGA +AGAGCTTTAGGTGGGGGAGTGACAAGTCTAGACTTGTCTTTGGAAAAGTCCTTCCAGCAA +GCTGGGTATTGGGTGGCCTCCCCTGGGAAGGGTCTGGAGTCCACTGGCAGGGCAATGCAT +CTCGCTGATTCCCAGCTGAGAGTTCTAGTGTCTCAGGGGTAAGGATGGAGAAGACAAGCA +GAGACACATCCCATCAATCTGAAGATACTTTTTACATTTTACATCTTTGAGATGCACTGT +ACAATTAATCAGCCAGTCATTGTGACATGGTTATCACCTGCAAACATGCTTCAAAATTTG +CAAAATGGCTTAGAAAATGCCAGGTCCGGTTACAGACGTCTCTTAAGAAAGGCTGCACCA +CAGACATTTTATGTGAGGAAAATAAATCAATAGAATAGACATAGATTACTCCAAGTTGAA +TAGCAATTCAAATAAGTTAGATTATGGGTGTGAAGACATTTTAGGAAATGTTCTTTTTTA +TTTTAGAAAATATGCACAGGAGTGTTATGATCAGTGTAAACGTCTGAATAAATCTAAAAA +AGAACTTCAATAAATGTAAAAATTTTGGCCAGGCACAGTGGTTCATACCTGTAATCCCAG +CACTTTGGGAGGCCAAGGTGGGAGGATCACTTGAGCCCAGGAGTTCGAGACCAGCCTAGG +CAACAAAGTGAGATCCTGTCTCTACAAAAACTCAAAAACCATTAGCCGGGTATAGTGGCC +TGCACCTGTAGTCCCAGCTACTCAGGAGGCTGTGGCGGGAGGATCGCTTGGGCCTAGGAG +GTTGAAGCTGAATGAGCTGTGATCGTGCCACTGCACTCCAGCCTGGGCAACAGAGCAAGA +CCCTGTCTCAAAACAACAACAACAAAAATTTTAATAAAAATTTTTAGGGGGCTGGGCATG +GTGGCTCACACACACCTGTAATCCCAGCACTTTGGGAGGCAGAGACAGGCAGATCACTTG +AGGCCAGGAGTTCAAGACCAGCCTGGGCAACGTGGTGAAACCCCATCTCTACTAAAAATA +ATTTTTAAAAAAGATTTAAAACTTAAGTTATGATAAAGCAGGTTTTTTTTTAGTTTAACT +ATTAGCATATTTTATACTTAATGAAACAAAAAATAATAGTAACATCTTACAATCTGTGGT +GTCTTGGATTTGATGAAATACAACACTTCAAGACTTCAGAGTCCTTGTGAATAATGTGCG +GAAGACAAAGTGGAAATGTGTGTGTGCGAGTGTGGTCAGAGCAGGGAAAGGCAGAGCAGA +GTGGCCAAGAACCGGTAAGAGCTTAGTCCTGAACACATCTCTAGTTCTAGACTATAAAGT +CCTGATGTCACTTTATCTCTCCATCTCAGAACTCACAGTGCCTAGAACAGTCAATGTTAA +TATTGCATCTGAACTGAATTATTCTTTAAAGATTTAATTAAAGTAGCTCTCTCTTTACTT +TCCCATGCATAACCACCCATTTGCCACATACTTTCACAAATTTCAACTGGGGAAAGCAGC +AAAAGCGTTTTTACTAAAAATGTAGAACCTACACTTAAGCCAAAAATAAGAGTTTGAGGA +GCGCCTCTCTCTGCTTGGGTGCAGCCCCAACCCCCCTTTGGAGCACCCACTTAAATGGTT +ATCTTCCCTCTAGTTCTTCGTCTTTGACTTTTATTCCAATTATGACCAAGTGCTTCAAGA +CTTTCTAAGATTATTGATTAAAAGCTTTTTGGCCATTGTCATACAATTTTAGATCTGAAA +GAATTCTGAATCGTTTAAGTCAGCAGTCCCCAGTGTTTTTTGCACCAGGGACTGGTTTCA +TGGAAGACAATTTTTCCACGGCGGTTGGGGGTTGATGATTTTGAGAGGAAACTGTTCCAC +CTCAGATCATCAGGCATTAGATTCTCATAAGCAATGTGCAACCTAGATCCCTCGCATGTG +TGGTTCACAATAGGGTTCATGCTCCTATGAGAATCTAATGCCACCACTGATCTGACAGGA +GGCAGAGCTCAGGCGGTAATGCTCACTCGCCTGCCACTCACTGGTTCCTAACAGGCCACA +GATGGGTACCAGTCCACCACCTGGGCGTTGGGGATCCCTGGTTTAAGTCAAATGCTTCAT +TATATAAAGATGAGAAAACTGAGGACAGATTTTTACAAGAATAGGAAAAGACAAGATGAG +CTTTGAAATTAGATGGTGTTGTGAGTTGAACTCTGCTGCCTTTAAAGATGTCTTCAATTT +CCTAACCCCTGACAACAATGAATGTGTCTTTATTTGGAAACAGGATTTCTGCAGATGTAA +TCAAGTTAAGATGAGGTCACACTGGATTAGTGAACTCTAATCCAATGGTTCATGTCCTTA +TAAGAAGGAAATTTGAACGCAGAGACTCAGAGAAGAGATTATGTGAAGATACAGAGCGCA +AAGCACAGAGAACACGCAGAGATTGGGGTGACATCACTACAGAACAAGGAACACCAAGGT +CTGCAAGCAAACACCAGAAGCGAGGAGGCAGCAAGGATTCATTGCCCTGCACGTTTCACA +GGGAGCAAGACCCTGCCAACGCCTTCATTTCAGATTTCTAACCTCCAGAACCGGGTGATA +AGCCACCCAGAATGGCTACCGCAGCCCCAGGAGAATAATTCCGATGGAAAGGGGCATAAA +CACTGATTCAGCCATTGACTAGTTGGTTGATCTTCTTTAATCACATTTATCTTCAAAGAG +CCCCAAGCCCCTTACCTGCAAAAAATGGGTACACACAAGGATTTGCTGTTTCCCCCAGGT +TCCATGCCCTATAACTTGTCCTGGCAATTGCTTCTCTCTCCTTTCGTCCTCCCTGAGTCT +TGGCTCTCAGGTCTCACTTCCTCACTGCCCACTACTCTTCAACCCCCTGCAACCTTGTGG +CTGCCCCTTCCACCTCCCTTCCACTAAGGACAATTCTGGGTCACTACCCTCATCTAGCCA +CGCCAAGGCCATCTGACATTGCACTTCAGTCTGAAATCTCCATTCCTCTCCTCCCTCCTG +GTTTTTCTCTTCCTACCTCTCTGAGACGTCATGGCTCCATCTCACTCTCTGGACATCCAC +TTCACTCCTTGCCTCCAATCCTGCCCTCCTGCCTAGTTTGAGCTGTCACTATGTGTTGCT +TAGATTCCTACCCCTAAGCTCCTTGCCAGTCTCTGACATCTGCAAATATTCCTCAACCTG +CCCCAACAAAGAGCTTTCTAGAGTGCATATCTGACGACGCCACTCCCGTGCCTTAAGTCC +TTTGATGGCTTCCCAGCTTCTTGCAAAGCTCCTCACTCTGGACAATCTGGCCCCACTCCC +CAGCACCTGCCCCATCTCCTGCTACTGCCCTCACCAGCACAACACTCCCACTATACCCTC +CAACCTGCAGTTCCTCCAGAAACACATGCTTTTTTTGTTTTTTAAGAAATGTAGGCCGGG +CGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGACCCAGGCAGGCGGATCAAGAG +GTCAAGAGATCGAGACCATCCTGGCCAACATGGTGAAACCCGTCTCAACTAAAAACACAA +AGATTAGCTGGGCGTGGTGGCGTGCACCTGTAGTCCCAACTACTCATGAGGCTGAGGCAG +GAGAATCTCCTGAACTCGGGAGGCAGAGGTTGCAGTGAGCTGAGATTGCGCCACCACACT +CCAGCCTGGCGACAGAGAGAGACTCCATCTAAAAAACATATATGTGTGTGTGTGTGTGTG +TGTGTGTGTGTGTATGTGTGTATATACATGTACACATAGATATGCGTGTATATACATGTA +CACATAGATATGCGTGTATATACATGTACACATAGATATGCGTGTATATACATGTACACA +TAGATATGCGTGTATATACATGTACACATAGATATGCGTGTATATACATGTACACATAGA +TATGCGTGTATATACATGTACACATAGATATGCGTGTATATACATGTACACATAGATATG +CGTGTATATACATGTACACATAGATATGCGTGTATATACATGTACACATAGATATGCGTG +TATATACATGTACACAGATATGTGTGTATATACATGTACACATAGATATGTGTGTATATA +CACACATATATACATCTATACGCACACATATATACATATATATACACACACATATATACA +TATATACACACACACATATATATACACATACACACACACACACATATATATATATATATA +AACTTGGCCAGGCATGGTGGCTCATGCCTGTAATCCCTGCACTTTGGGAGGCCGAGGCAG +GTGGATCACTTGAAGCCAGGAATTCGAGACCAGCCTGGCCAACCTGGTGAAACCTCAACT +CTACTAAAAAATACAAAAATTGGCCAGGTGTGGTGGCGCACACCTGTAATCCCATCTACT +TGGGAGGCTGAGGCACAAGAATCACTTGAACCTGGGAGGTGGAGGCTGCAGTGAGCCGAG +ATCACCCACTGCACTCCAGCCTGGGCAACAGAGCGAGAGCGAGAAAGAAAGAAATACAGA +AAGAAAGAAGGAAAGAAATAAAGGTATTAACTCAAAAAAAATTTTTGTTTAAATGTACCT +CCCATACTTTTTGGCCCATTTAATTTTTTATTATGGTAGAATATACAACAAAAATGTATC +ATCTTTAACCATTTCTAAGTGTGTCATTCAGTGACATCAATTATATTCACAATGTTGTAC +AGCCATCTCTGCTATCTCTAAAACACACTATTTTTCGTGTGTCTTTGCACATATTATTTT +CTCTGCCTGAAACCCCATCCCTATTTCCAGGTCCCATTAGCTTAAATAAGTCAAAAGTGT +CTCCTACTCTTGGGGGATCTCCCCTGGACCCCGTGACCTTGGCTGAGAAACAGTTCTTGG +CTCTGGGAATAAGAACCTACGGTCCAGTCTATTGTATAGAATACAGACTGCAGCTGGGCA +ATACTTGGCCTTCATGCTCCAATCCTGTGTCTTTAGCCTTAGCAGGATCTCTGATGCACA +GTGTCTGGCACACAGCAGATGCGTGTCAACACTGTGGATAAATGGATTATAGGAAGTTAT +ACAGTCAAGTTAGAAGGAAAGATAAGAACCCAGTCTCCCTTCATTCTCTCTCCTTTTATC +TCGAGCTTTTTATTTTATATATTGCATTCTCACTTCACTGTTTTTACCTAGAAAGGTTTT +TCTATTTAAAGCAGATGTGAAATGTCACTTTCCTAAAGAAATATGACTTCCATCTCATAC +ATAATCTGTCCAAAGATTGTCACTTTTGGGGGCAGGTCACCTACCTTCATATTACAGGAA +AACAGTGTGCAGTCAAAAGTACCATGGTTACATAGGTGGGACAAAAATGATATCACAGAA +AGAATATGTCAGCTGCCCCCAAAAAAATTCAACTAGGAGGGAAAAAGATGCCAAAATGGA +GTCTAAGATATCTGCTATTTAGCCTGAATGTTAACACTGCCTACCCAAGAAAGAATCTGT +TAACATATATTTGAGCCCTGGAAGCGTCTCTGGAAAATAAAGCTGCACAGGCCTTTCCTA +CACAAGTCTTCAAAGCAGGACCAATAACTTTAAGACCGGAGTCGCGGTAAGAAACTTCAG +TATCTATGACTGTTTTATTTAAGCACAAACAAGAGGAAATATGCATCCCCCTTTTTAAAC +CTAGAGGCATAAAAAGAGATTTAAACATATAATTCAAAGTATCTTTAGTGGTAACATCCA +GAAAGATCACAGGATGTTTTTTCCCCATGTTAAGTCTGTGCCTGGGGCTCCCATTCTCTG +TGCCTTGTTGTTTCTGGATGTAATAAAATCCCAGAAGTGGGAGGAATATTTGCAAGTCCC +CACACCACAATGGTTGTCTTCGGGAGACCCAAAAGATTAAGCATCCAGTTAAGGCAGCGC +TTCTCAGGCACGGCACCACGGGCGTCATGCGGTGGATGACTGTGGCAGGGACTGCCCTGG +GCATCTTCCTGTGTAGCATCTCAGGCCCACTCACCAGATGTCAGTAGCAGCCCCACACCC +ACACCCAGTTGTAACAACCAAAAGAGTATCTACAAACATGGTCAAATGCCCACAGTGGGG +CAAAACTGTGGTTGAGAACCACTGACTTAAGGCGAGGGAGCATCTAAGAGGATGCTGTCT +GCCACTGAGTGCCTTCAGAAGAGAGGGATGCAGCAGCTCAGGCCGTGACAACTTTAGATT +CTTAAGGCTGGAATTTTCCCATGTGTGCCCATGGCAAGAACAGTAAAACCTTAGGGGGAA +AACGAGTTGGGTAATTGTAGTCAAGGTAGCAGGGAAGAAAAAAACTGAGAAAACTTGATC +CACTCCATTTAAGGGAAGACCCAAGCTCCTCACAAGCGTAAGGGGACAATGTCTGGGTTA +TTTTTTATTTTTTTTTATTTTTTGAGATGGAGTCTTGGTCTGTCACCAGGCTGGAGTGCA +GTGGCGCGATCTTGGCTCACTACAATCTCTGCCTCCCAAGTTCAAGCAATTCTCCTGCCT +CAGCCTCCCGAGTAGCTGGGACTACAGGCGCCCACCACCATACCTGGCTAATTTTTCGTA +TTTTAGTAGAGACAGGGTTCACCATGTTGGCCAGGATGGTCTCAATCTCCTGACCTCATG +ATCCGCCTGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCACGCCTGGC +CAATGTCTGGGTTATTAAAGAGTAAAGGAAACAGAGCAGGAGGGGAGGGGCTGCACTAAG +ACAAAAAGGGAAAGGAGCGCTTGGGAGCCACATCGGGTGCAAAGTGCTCCTGGGACTCAG +CTCTGAAAGCAGGACCCTGAACAGTGGTCAATGTCCCCACCCAAGACAGAAGGTTACCTC +CCAAAGCTTCACTTCACAGAAAGAGTGGACAAAGAAGAAACGATCCTCAAGGTAAAACAC +AGTATTTTCAAATGCTTTACTTGGTCCTTCCAGGTATTTCTAAATGGACCCTTAAATCTC +TTTCATTTTTTTTTAAAAGAAAAAATCTTCAGTCAATTACTTCAGAGCCATCTCCTCTCC +CCACTGCTCTGCTCCCCTGCCCCAAAATTGAGTATAAAACTAGTAACTGGGACATTCCAG +AAAAGAGTGACAAAGGTCAGCCATGCAGAAATCTCAGAATCCCCAGAGAGGAAGTCTCTT +CCATCCTTAAATTTCCTCTCTAGGAATAAGGAAATTCTACATCTCTTCAATTTGACTCCA +GTTTTTATTTTGTAAACCACAGCCATGTTTGCTATTTAAGACTGATGCAATCATGAAAAA +CTTTTAAGAAGTGGTAACCACTTCTCTAAAAAGAAGTGAGAATGACACAGAGTGAAAATC +AAAAAGGGTAAAACAGAATGAAAAGAACTATGAGCTAAGGAATTTCAGTTTGATTTTTCA +GTCTTTCTAGAGTATCAAATATGATCGTGTTAAACTAAAATGTCAGATTTTTCCATTGCT +CATAATTCCTTAAGTCAATAGAAATAACCAAAGGTGCCATAAGCCAAGTCTGCATCTTCC +TGTACATTAGAAAATTCTCCCCAGCAATCCCATTACTGGGTATACACCCAAAGGAATATA +AACCATTCTATCACAAAGACACATGCATGCGTAAGTTCATTGTAGCACTATTCACAATAG +CAAAGGGTGGAATCAACCTAAATGCCCATCAATGATAGACTGAATAAAGAAAATGTGGTA +CATATATGCCATGGAACACTATGCAGCCATAAAAAAGAACAAGATCCTATCCTTTGCAAG +AACATGGATGAGCTGGAGGCCATTATCCTTAGCAAACTAACACAGGAACAGAAAACCAAA +CAGGGCACCTTGTCACTTATAAGTGGGGGCAAAATGATGAGAACACATGGACACAAAGAG +GGGAACAAATGACACTGGGGCCTACCAGAGGGTGGAGGGTGGGAGGAGGAAGAGGAGCAA +AAAAAGGGAAAAAAAATCACTACTGTGTATCAGGTTTAGTATCTGGATGATGAAAGAATC +TGTACATCAAACCCCTATGACACATGTTTACCCATATAAGAAGCCTGTACATGCACCCCT +GAACCTCAAATAAAAGGGTTTTTTGTTTGTTTGTTTTGAGATGGAGTCTCATTCTGTCAC +CCAGGCTGGAGTGCAGTGGTGTGATCTCAGCTCACTGCAATCCCCTCCTGGGCTCAAGTA +ATCCTCCTACCTCAGCCTCCCAAGTAGCTGGGACCACAGACGTGTGCCACCATGCCCGAT +TAATTCTTTTACTTTTGGTAGAGATGGGGTTTCACCATGATGGCTGGTCACAAACTCATG +AGCTCAAGTGATCTGCCCGCCTCAGACTCCCAAAGTGCTGGGATTACAGGCATGATCCAC +TGCGCCCAGCCAAAAGTTTTTTTTAAAAAAGAAAATTCTGGCCCGGCCCAGTGGCTCACG +CCTGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGCGGATCACGAGGTCAGGAGTTCAAG +ACCAGCCTCGCCAATATGGTGAAACCCCGTCTCTACTAAAAATACAAAAATTAGCACGAT +GTGGTGACGCGCACCTATAGTCCCAGGTATTTGGGAGGCTGAGGCAGAAGAATCGCTTAA +ACCCGGGAAGCAGAGGTTGCAGTGAGCCAAGGTTGCACCACTGCACTCCAGCCTGGGCGA +CAGAGCAAGACTCTGTCTCAAAAAAAAAAAAAAAAAATTCTTAAGAGGAAGATAGGTGCT +ATGTAAATAACATTTGGGATATTATCCTTAAGGGTGTTCACAGAATGGAAGAGATAATGC +AACAAAAGACCCCAGCTGTGAGACCCTGGTCCTCATAATGTTCAGCCCAAAGATGGAATA +GAATGTTGAGATCCAAGTGGCGTATAAAGTATCAACAAATTATTCCCACGGTAAAACACT +TGACCAAAGGAGAACTTAAGCCTTGAATAGTTAATCTGTTCTATAATATCCATTACCAGA +GAGGCTGAGATGTTGCGGTCTAAAAAAAACAAAAAACCAAACCACTAGCTTAAGAATTAA +GAGATGAGTGCTAGTCCTATCTTAGCCTAACTAAACTTTGTGAGTTGAGAACATCACATA +TGTCTCTCAGCCTCAATCTTCACATCCGTAAAATGAACTGGAGTGTGAACGACTCCTTAC +CAGTGTCATTCATTCATTCATGCATTCCACAAAGTTTTTGAGCCATATAATGTCAAGCAC +TATTCTTGGTGCTTGGGGAAACAGAGGTGAACTAAAAAGACAAACAAAGCTTATGTTCCA +GATTCTGAAACTATTATAAATTGGTGTTTTCACACTATGGGTTGTAAAATCCAGTTAGCA +GAACCAGATGAGCACTTTAAAAGAAGAAATGGCATCAAATAGTATAAAATGTCAGAGTAC +ATCACATATAGTAAGGAGAAGTTCTGGTTCATAAAATTTTGCTTCAGTTATTGATAGATT +CTTATATTTGTGAGGATTGCAGGTAAGGAGGTATAAGGCATTTCTGAATATGGGTTGGTT +GTGTCAAAGGAGTTTAAAACTCCCTAATAAAAGGCTTCATTTTGTTTCAGCCACTGTCCT +CATCCTAACCTTCGCTTTAATTACTTCTTAGGAACATCCTGCCCATAGATAAAATCTCAT +TACTTTCCCGTTTGCCCCATGATGGCATTTTGGATAAATATCAGAGATATTTTTCACTCT +TTTCAAATCAGTATTCCCAACCTCTCTGGGTAGGATTCCTTTTTATATCAGTCCTTCTTG +TCTGTATTACTTGTCTGGTGATTAAGAAAATACATAGTGGCCAAAAGCCACAAGAACTTT +TAATGGATTCATAATGTATTGGTCCTAAAAGCTTCTACGTAGAAATACAAAGAGTGCAAA +CACACGGAGGACACATTATTCATTCCATCGACCAACCATGTTTGATGTTCAGACAGGTGT +GCAGACTTCTTATGCCCTGAGGGGTCATGGGCACAGAGATGAGTAATCACTCTTCCAGGC +CCCCACTTTTATTTGGCCATTTTAAAATCACTGTGTTCTTACAGATGACTGCTGAGGGTG +GTTTCTGCTTGTTTTAATGCTTGTTCACCCTCTTTTCTTTCAATTAATGCAAACTACTAA +ACCTAGCTACATGAGTTTGTTTTTCATTACTGTTATTCATTTGCTTTTTAATAATTTTTT +AAATCTCACAACCCCAGGTTCCTTCGAACAGCTAACAGGAATTGTGAAGATAATCTTTCA +GAATCTGCCTAGAGGTACACCCAACCCTACAACTGCCCTGGTTTTGACAGAAAACATCCC +AAGGCAGCCATGACCATAACTTGGAAAATGAAAGGAGGTGAAACCAAGAGACAAGAAGGG +TAGAAGGGAACTAAAAGAAGCAAGCAGTGTCAATCTTCCTGGGAATCTGGATGCTTGCAC +ACCGATCAAGGTCCACCTGAAGTCACAAAACCACAGCCCCAGCTTCTCAAAGGTTCCCTC +CCTCCCCCGCAAGTCACTTGAGTTTCAGTCCATTATCAAGCTCTAGCTTCCCCATTCTGT +GTGGCCCCTATTAAATTATACATAAAATTTATAAGTTAGAAGGGGGCTGGGCAAAGGGGG +AGCCCAGGCCCCTTTATTACAGAGGTCTGAGGGGGGCCACTTGGGCAAGGCAAGGTCAGC +ACTGGAGAAAGTTTCCTGGCAATCAGAATCCCCCAGCAGACATCAAGCTGCTGCCTCCTG +CCCCCAACTTCTACAGACCAGCTCTACCCCTTCTCTGTTATATTCAACATTTTCCTGTTC +CTGGAAATCCCAGCCACTTTTGGGGAAAGATGGCTACCAGGTGCAACCAAGAGAGGAATG +CTGCTTCACACATCCCTACTGTCGGCAAATACACAAACCTAAAATACTTAAAACTAAGTT +TCATGCTGTCACCTTTACCATGTTTTTTTCTAGGTTACCCATTTTTTCAGCTTAAAATGA +ACAAAATGTGACCTGTTCTTCATTAATAAGGAAAAAATTAACTTCTGGAAAAACCTGATT +GCTTATTTGGCAAATTACAGAGAAGGTCATTTAACCAGTTCCCAGCATTGGCTATGAGAT +GAGGGACCCAGCCGGGAGGATGGCTAAGCTGCTTCTGGCTTTCTGCTGCCTTGTGCCAAT +AAAGGAAGGGCCTCCCTGATGGTGCTCCTGGCCTTCAAAGCAATCTCATACTGGTAAGTA +TGAAGGAATAACTGCTTCTAAAGGTACAGCAATTTCTAGTTTTTCTTTAAAAAAAAAAAA +ATCTCTTGCCTAGCAATTTCTGTAAGTTGCTCTCAATATTCCATAACAAAACCCAGGACA +GTCATTAGCAAGACCTTGAACTGAGTCAGTGCTTAACCATCATTTTACTAAAGAGAAAAA +TCGGGAAAGTTGTCGTAAATTACCTAAGCAACTAGAAACCAAGGACTTCAGATTCCTCCT +TTTTTGTTATTTACCAGCTCAACAAACTCAAAGTGAGCTTGGAATATCTATCAATGGAGA +AGTCTAGTGATCGCATAAATAGTACTAACTTTAAAATCTAACTTCTAAGTATACACATAT +TCTAAATATTTAATGAGCCATCTATCTCTGTACTTTGAATCTAGAATAGCTTATTAGCTA +GTTACAACCCAACACCACCCTGGTACATCTTTACACTAACAATTTTAAAGCCAGGCAAAC +CCCAAGTTATGTCTAGGTTTTATTCCAAGCAAACTTAACTTTACAAAATTAGTAGTTACC +AAATTTCTGAAGAGTAGGTGATCCGGGTGGAGATGAATTTCCACTAGGAGACAAGTAGAG +ATAGCTTTTGTTCACTCCTGCATCAAAATCAAACGGGGACTGGTAGTCCTCATATAAGTC +CATCTCTCTACAATCCATTCCAGACAAACGCAGAATGCATGGCTGTCTAATCGCCTGATA +TCAGCCTTCAGTTGAGTGCCGCTTTGGCCATATTCCCTTTGTAGGGTGCAACTTCACTGA +AGAAATCAACCCCAGGAGTTAGAGGCCCTGGCTTCTGGGCCCAGGTGCCAGCATTTCCTT +TTGGGAGCCTTCACGCCCCTCCTGATAAGCAGACCTATTTAATAAATGATTTATCCTGAG +CAACCTTAGGAGGGGCTCTATTCACCACCTGGTGTTAATTTCGATCAACAATGAAAAACC +TGGGCAGGGAGCGAGCTTTCCTCAGTCAACAAAGAAGGGCAGGGTTCTGCAATATGGCCC +AGAGGTACAAACAGTTCAGGCAAACATCAGACACTGGCTGACTTACAACAAGAAACTACA +ATTTATTTAAAATAAATAAATAAAAAAATCAGCTGACCATGACTACACCAGGGCAGACTT +AATCTTCTAGGACAAGGAGGGATTACCAGTCAGTAATCTCCCACAAATGCCATCTGAGTG +ATACTTTTTTTCCACCCTGGATTACAGTAAAATTCTGAAAGCCAAGCTTCCTGGTTTAGC +AATCAGCTTTCTAAGCACAACTTGGTATAAAAATAAAGCTGTATTTCCATGATTACTTTA +TCTAATGTGGAGTCTGGCTGAGTGTCACAAAAACTTCAGACTGACTTTTCTTTTCTCTCT +CTTTTTTTTTTTTTTTTTTTTTTTAGAAAGCTGGTGCTTCAGTTACATGCACTCAAAGGA +GAAGAATCTACTTTGAATGGAAAGCTCCCGGGTATTCCCACACCTTCTTTGTTTGTCTAA +GGCCATGGCTCTGCAGAGCTGCAATAAACCTGCGTACCCACCCTGCAGAAGGACTGGGCC +ACAGCTAGCTTGTAAAACAAAACTAAGTCACCAAATTTATTTCCTTTAACACAGTCTCTT +AGCAGAACCTTTCTATGCTGACTGTGGCCTTGGCTCAAGCAACAGCAATTGCAGCTCCTG +CTGGTTCTACTAAGGAGGTAAAAATAAAGGCGACTCGCTTTCAGGTGGGCAATGATCTGT +TACTGCATAACAAAAAAAAAGGCAGTGTTCTAATCTAATCTAAAAGGCGGTTTTCAAATC +TAAAAAAAAAGAGCTCAGATATACTCTCCTTGGATTGGAAGCAAGTATGAAACCTAATAT +ATTTTAAGCATTAAAAACATCAGCATGTGTCTAGTGTATAAAATACATATGCACCAAGAT +GGTCTGTATTCATCTTGTGATTTTTTTTTTTTAAATACAGAATATATGCTGGATGATTTT +ATTTGTTATTTTTGTTAGTCTCATGTTGTACTCTATTTACAGTAGGTCTTTTTTTGTTTT +GTTTTCGATACAGAGCTTCGCTCTTGTGACCAGGCTGGAGTACAATGGCACAATCTCAGC +TCACTGCAACCTCCACCTTCTGGGTTCAAGTGATTCTCCTGCCTCAGCCTCCCAAGTAGC +TGGGATTACAGGCACCCACCACCCACTATGCCCGGCTAATTTTTGTATTTTTAGTAGAGA +TGGGGTTTCGCCATGTTGGCCAGGCTGGTCTCAAACTCCTGACCTCAGGTGATCCGCCTG +CCTCGGCCTCCCAAAGTTCTCGGATTACAGGTGTGAGCCACCGTGCCCGGACTATGGTAA +GTCTTTTTTTTTTTTTTTTAAGTTTATTTTTAACAACAAAAAAATCTGTATTTTTCTCCT +AAAAGGTACCAAAATTTGGGCAACTATAAATGTTTCATTCTATACTTAGAAATAAAATAA +ATGGTTTCTTTTTTATCATTATCTGAAAGAATGGATTGTCTGGCTTCTTGAAATCCATGG +CCTCTTACTGGGACAGGAAAGGCATTGGAGTTATGTCCCTAGACTAGAAAGAGTATGGTT +CATGAGGTCCCTGGCCCTCTCCATAACTCTGCATTTGGTCACTAAATATTGGTAGAAAAA +GTATTTGTCCATTACTTTACTTGTTCCACCACCTAGAGCCAAAGGCATTAGAAGGTAATT +AATAGTGATACGGATAGAATGCAAGCCACAGTCACCTCCATCCTTCTCACCATCTCTCAA +GCCCATGTCCTTGACCTTTGGTATTTACATCCATGTGACACGCTCTACCTGAAATGTCAC +CTTTTTCCAGCCTGTCAAAGTTATTCATCCTTCAACACTGAGGCAGAAATGCCACCTCTT +CTTAGAAGCCCCCTAGTCTCTGGCCCCCTCTTCTCCCAGCAGCAGCACACAGCATGTGAA +GAGCCCCCTGACAGGCGCCTGTGCCTATCCAGGGCCTCTCCAGGGCGCTCTACCGGATAC +CTGCCCTGAAGGTTTGGCTCCTAATCAATGTGGAATTAAAAAAGCAAATGATGGCTCATG +TAGATGTTACATGCCTTATTAATAAATGTGAGCATTTCAAATTTAAGTAATTGCCTAAAA +TTTTTATTTTACCTGCTTAGATACAATCTTAGGACTTTTATGCAACATCCTGGCTCTTTG +AACCAGTTTTTGTTCTCATTATCTCCAGTCAGATCCCAGTCAAGACATTCTAGCCTACAA +GAAAAGTGAAATCTAGAAGTGGGAAAAGCATGGGATGGGTTAATGGAATGGCAAAAATTC +AGTTAACTCAACAGCCAAATACAAAGTAGAAAGGAACTGAAAGACATACAAAATGGAAAT +GTAGCTTGGGGGCAGACCATTAAAGACTTTAACAAATTTTATACTTAATATACTGTGCAA +AAAAAAAAACAGGATTTATGAGTCATACGGAGAGTATAAGTTTTATAAAGATGACTCTAG +AAATGGTATAAGGATGCACTGCAGGCATAAAGAGGCTAAAAGAGAGAGGACTCAGAAAGA +GGCTATGGGTACAATCCCAGCAAGGAGGAGAAAGCCTTGTGATATGGTTTGGCTCTGTGT +CCCCACCCAAATCTCACCTTAAATTGTAATAACACCCACATGTCAAGGGCGGGACCAGGT +GGAGTAAACTGAATCATGGGGGCGGTTCCCCCATGCTCTTCTCCTGATAGTGAATGAGAT +AGTTCTCTGACGGTTTTATTAAGAGATCTTTATAAGGAGAACAGATGGTTTTATAAGGAG +CTTCTCCCTTCGCTGGGCACTCATTCTCTCTCCCGCCACCCTGTGAAGTGGTGCCTTCTG +CCATGATTGTAAGTTTCCTGAAGCCTCCCCAGCCATCTAGAACTGTGAGTCAATTAAACC +TTTTCCCTTTATAAATTACCCAGTCTCAGGTATTTCCCCATAGCAGTGTGAGAATGGACT +AGTACACCTTGGTATCGGGGCAACTCTTTTTATTTCCTGTTGTGGACTAGTCGGCCTGGG +GAAGAACCAGGTAAGATTTGGTCCTGTCCTGTGGATAATTCCACTTGGCTCTTCCAAAAG +TACTTCAAAGTCAGCATGCACAAGACTGAATTCACTGGCTTTCCTCACAATGTTCTTACC +TCTAGATTAGGCATCCTGAGTCTCCTAGACCTGACTTTGAAGGAATCACATCCAAGCACT +CTCACTCCATATGGAGAAAGCACGAAGAGCTATCTACCAACCGGTACCACAGGCCTTCTA +ACCTTTCCTTCATTTCCATTGTCCTCATCCACACCCTACTTGAGACCCAGGTGGAGGGTG +AGACCCACTCTATTGTTACTATGTTTTTCCTTCTGGGAGGGACCAGGCCCCACAGCAGTA +TGGTAGACATCTGCTATCTTGTCAATTTTGCCCCTCTTCCCCTAGAGGAATTTCACCTCA +CCTGCTCCCTGGGGTTCTCAGTGGGGAGAGAGGTCCATAGTTCCCACCCCCTGGCCCCAG +GCATGGGCCTGTGCTTCAGATCTGGTCCACGCAGACACCCCATCCCCTTGTTCACAGGGA +CTGGCCTAAGGATAGACATCTGACCCAGACACTGTCAATCAATCAGTGGCCTTCCTTGAT +GTTTACTCTGTGAGTAATGGAAGAAAGTGACTCTCTCTGTAACCTGAGCTGTTGGGTGGG +GCTGGCAGCTCCTTCCCTCACCAGGCCAATGGGCAAGAGACTCAGTGCTGAGACTGGGAA +GGGACAGAAGGAGAAACAGAAACAGACAGGTAAGGGATGGCGCAGCAGCATCTAAGCCCC +TGCCTCCAGCTACCCTGGGCTTCCCAGTTATTAAACAAACACAATTTTGTTCTGCTCCAC +TTGTGGCTGGAGTTGAATTTCATCATTTCAGTAGAAAGAGTCCTAACATACCTACTTTCT +GACCATATTTCCCACTATTACTCAACCATGCTTTAGCCAAACTTGACTTTCCTGTTTGTT +GAACACATCCTAAACTTAGCCCAGACAATTTTCTCAAACTAGAGTTTCCCCTTTTCCTGT +AAGTTCCTACCCATTTAGCAAGCTCTACTTATTAAGTCACATATGAATAGTATACATGCA +AGGGACATTCACTTTAGATGCTACCTGAAATGGAAAAAAGCAATACAAATGCCTACTAAA +AATGGATTATTTAAATGCTAAAAAGAACATTCAGGTAATAGAAAAATATGGAAACACTGA +CATAATTATATAAAAATATTTATGAATTTTATATGGAAAGGTACTGATACAGTTAGCAAA +CAAATCAGGTTTGAAAGAAGGTTGTATTGTATGGTCCATGTTTGTGTAATAATTTATGAG +AGAGAAAACCACAAACCAAAAGAAAGAAAATGGGCAGAAAGAGAAATCCATTCCATGACC +CCAGAAAAGTGCTCACGCACCACTATGCCAGCAGAGGGAGCCCAAGGGCAGTTCAGAAGT +CAACTAGGTGCAGCCAGTAAAGTGCGTATGTACTGCAGGGTAATAACCGGAGACGACTCA +TGTCATTGCAAACGGAAATGGTAGTAGGTACAAATGACTATAAAGAAAATTAAGTTTCTG +TCTGCCTGTTAACTCATCACTCAAATATGTCAGTGTAAATTCTCCACAAACTTGAAAGAC +ATATAAAGGACAGTCTGATTTAAAAGCTATGAAACACAATATTTACTTGGAGGGCACGTC +AAAGGGAGACAATGTGGCTGTCCACCAGGAGAGGCAGGCCGCAGATACTTGGGGAATGCA +GACGTGTCATGGTGATACAGCAGCTGGCTGGAAGGGGCTCCAACTAGCCAATATGGGACA +ATCAGGCCGCCAAAAAAATTAGGGACAGTCAGGGATTATAAACCACTGAAAAAAACAGGA +ATCCAAGAGTCCAAGAAAGTAATAAATAGAGAGAAGGAAGAACTACAGAAGAATGCCACC +CTGACCATCTTTGTAAAGATTCAGACAAAAATCATCGCTGGATGCTAAAGCTCGGGAGAA +ATTTTGAGGAAGAAGATGATATTTAAATGATGTTTAAAGTGCCTCTCCACAGATTAACTA +GCTGCCAGAAGGAAAAACATTGAGTGGAGATCACTTCTTGGCCTTTTGGCTGAGATCAAG +TGTAGTAACAGTATAATGGAGAAAAGCCCCACCCTGACTGAAGGATAGAGATGGCCATAC +CCCAGTGAGAGGCAGATGGACCGCTCTGAATACCTACATAGTGTTCAGGCTTGGAATGCA +GAACCTGAATCGAATCATGAGGAAACATCAGACAAATCCAAAACAAGTTTTTGTTGGGGT +TTTGTTGTTGCTTCGGGTTTTTTTGCTTTTTTTTTTTTTTAGTTTTTTTTTTTTTTTTTT +TGAGACGGACTCTCACTCTGTTGCCAGGCTGGAGTGCAGTGTCGTGATCTTGACTCACCA +CAACCTCCGCCTCCCCGGTTTAAGTGATTCTCCTAACCTCAGTCTCCTGAGTAGCTGGGA +CTACAAGCGCACACCACCACGCCCAGCTAATTTTTGTATTTTTAGTAGAGACGGAGTTTC +ACCATATTGGCTAGGATGGTCTCGATCTCCTGACCTCGTGATCCACCCGCCTCGGTCCCC +CAAGGTGCTGGGATTACAGGTGTGAGCCACCGAGCCTGACCGGAAGGTTCTAGTTTTTAA +AAGAGGAGGGGCTGCATTCTTCAAAAACATCGATGTCATAAAGGACAAAGACTGTGAAAA +TCCACATTAAAGGAGACTGGCATTACTAGGTCCATTGAAAAAACTGGAATATGACCTCAG +ATTAGATAAAAGTCTTGTATCAATTTCAAATTTACTGGCTGGGCTTGGTGGCTCACACCT +GTAATCCTGGCACTTTGGGAGACCAAGGCAGGCAGATCACCTGACATCAAGAGTTCGAGA +CCAGCCTGGCCAATATGGTGAATCCCCGTCTCTACTAAAAATACAAAAATTAGCTGGTTG +GGGGGGCACGTGCCTGCAGTCCCAGTTACTCAGAAGACTGAGGCACAAGAATTGCTTGAA +CCCGGGAAGCGGAGATTGCAGTGAGCTGAGATCGTGCCACTGCATCCCAGCCTGGGCAAC +AAGAGTGAGACGCTGTCTCAACAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAATCAAAT +TTACTGACGTTGACAACTGTGGTGAGAATATTGCCTTTCTTAGGCAATGGCAATATATAC +TGAAGTATTTAGGGGCAGACGCCATGATATATGCAACTTCCTCTCAAATTGCTCAGAAAA +TAAGAGTATGCATGTGTACAGACATCCACACACAGAGAGACTGGTCAACCGGATGGGGCT +AAACGTTAACAGTGACCCTGAGTAGAGAATGCAGGTGTCCTTTTTTTTTCCCCCCATCAA +CTTTTAAGTTCCAGGGTACATGTGCAGGATGTGCAGGCTTGTAACATAAGTAAGTGTGTG +CCATAGTGGTTTGCTGCACAAATCAACCTATCACCTAGGTCTTAAGCCCAGCATTCATTA +GCTATTCTTCCTTATGCTCTCCCTCCCCCACACCTGTGTTGTTGGCACATATACACCATG +GAATACTATGCAGTCATAAAAAGGAACAAGAGCATGTCCTTTGCAGGGACATGGATGGAG +CTGGAAGCCATTATCTTCAGCAAAGTAACACAGGAGCAGGTATTTACACTATTCTTATTC +TTGCAATCCTTCTGTAAATTTGAAAAGGGCTAAAAAACAAACAAACAAAAAACAAGAACT +CCTCTGCCTTAGATTCAGCAGCCCTGAGGGCGCTGTGGAGAAAGTGTGTGGCAACCACCT +CTCACAGCAATCACGGGGGCAGGGCCTAATGGGACTGGGCTCCAGCCACAGACACACAGG +CACATACCGGCTCCAGGCCCCTTCTGAGAGCTGGAAGGGCTCTCTCCACCTTCCACCGAA +GCAGCAGTTGGTTTACCTTCTACAGAAAAGAAGTCTCCCCATCATATCCCATGCTGGTCA +CATCTTCCCAGAGGGAGACCAGTGGGGACCCTGTTGCACAGGGTGAGAGGGCAGAGAGGC +TGAGAGGTTAATGAACACCCCACACCCCACACCTCTTCATTCCCCGACACTGTGCCACAA +TAAACAAACCTTGACTCCAAATAAAAAGTACTTGATTTTAAGTATGAAATTCAATTTAAA +ATCACAAGGGTAGATGCTCTCTTATTTACAAAATTTCTCAGCTAATCCTCAAAACCTCTG +TGAGGTAAACCTCTGCCTCTCCCTATTTTTCAGAGGGGAAACAAGACAAGGACAGTTCCT +GTAAACCTGTCTTTGGGCATAGAGCTAGCAAGTAAAGGAGCCGCAGTTTGAAGCCTGGTA +CGTGCCTCCAAGTCCCTGTCCTCTCCATCCTGTGGCTGTAGCCTAGAGCCGGGCAGTAAG +GATAAGCCAGTCCCTCACATCTAATGGCCCTGGGGATCTTGCTGTGATGCAGAGTCTGCA +TCCTGGTGATGGGAGGCTGCTGGCCCTGGAACCACATGGGATCACACTTGGAGTAACAAG +GTGATGGAAGAACTCGAATGGAGGCTGGAGAGTAGGAATTTGGTTTTCGTCAGATTAAAG +CAACAATTCTTCATTAGAATTTATTTAATCCCTCAATAACACGAGGTTAGTCATGTTATC +TCCAATTTCCAGAGGAGTGAGCATAAGGAACTGAGAAATGAAGGAAGCCACCCTACAGTG +GTCATTTTCCTCTCACTGCATCTAGGCCGTGGGGAGCCAAGTCGAGTAATTAGGAATGGG +AGGCCAAAGCCACGTGTCAGAAAGATCATTCTCACCCCTGTCTGAAGCTGGACTGCCGAG +GGGAGAGGGAAGTCAGGACAGCTACCCAGCAACAGCGCCAAGGGTGTTCTGGACTGAATT +GTGTCTCCCCAGCTTCATGTGTTGAAGCCCTAACTCCCAATATGGCTGTATTTGGAGATG +GGGTCTTTAGGAGGTAATTAAGATTAAACAGGGTCATAGGGTGAGGCCCTAATCCAATAG +GACTGCTGTCCTAGTAAGAAGAGACACTAGGGATGCTCACGCAAAAGGCCTTTTTCACAG +AAAAAAGGCCAGGGAGGACATAGCTAATTTTTTGTATTTTTAGTAGAGACGGGGTTTCAC +TGCATTAGCCAGGATGGTCTCGATCTCCTGACCTCGTGATCCGCCCGCCTCGGCCTCCCA +AAGTGCTGGGATTACAGGCGTGAACCACTGCGCCTGGCAGCTCTCTGTCAACCAGGAAGC +AAGCCCATGCCAGAAACCTATCTACCCTGCCACCAGCACCTTGATCTTGGACTTTCAGCC +TCCAGAATCGTGAGAATATAAATTTCCATTGTTCAAACCACCTATTCTATGGTATTGTTA +TTGCGGCCCAAACCAACTAATACAAAAGGCATGTGCCCTGCATGGAACAGAAGCGGGAAC +AGCAAAGCAAAGACACACTGCATGACACCATGAACAGACAATCAACAGATGCTGGAGATC +AACTGGAGGACTTGGGTGACGGGCAATGAGAAGCCAACGTGTGATACCCCAGCAGGAGTT +GTAAAGGACAGTGACCGCATTAATGAAGATGGTGGCAAAAGAGAGGCAGGACTGAAGAAC +AGAGAGAAGAGACTTTAGGTGATAAGAGAATGAGCTGCATTTTGGCAGATTTGGTTAATA +GAGCTCACAAGACTTCTGGAGTAAATGGCCAGCCTGAGGTTAGAAATTAAACTTCTATCC +TCAGGGAAAAAGTTAGGGGCTAAGATATAAAATGTGGGAAACCCAGAGATCGTCAAAAAA +AAATTTGAAGAGAAGAGAGGCCCTATGAAAAGGAGTGGAAAAATTAGTGAACACCTACAA +TCAGCATGCAGGCCAAAGAGCCTAAAAAGGGCAAGCAATGACCTTTAATGATGACAATAA +TTATGACTTATCCTTAAGGAACCCTTACTATGTGCCAGACATTCTTCTATGCACTTGCAT +CAATTTTATGGGGTAAGTTTTTCCCTACCCTTATCTTACAACAAAACTGAGACACATCAA +AGTTAAGTGTCTTGCCCTAGGCACAGAGCTAGAAAGTGGTAAAACTTAGGATTCCAATTC +CATTGCTCTCAAGAAGCAAAACATCTGGAAGAAAACCTTGAGTGACCAATGTCACAGGAA +TCAAGGGAGGAGAGAAACTGGATAAGATCAAATGCTAAAGAGACGCAAGAAGAAGCCACA +GGACTTGGGGTCTGGTGATCTCGCACTGAAGTTTTAGTGAGAGTGATGGTAGATGTCAGA +TAAGCAGAAGTGGTAGGCAGTGGAGGAAAGGAAAGGGAAGAAGCGAATGAAAAGAAGTTT +TAAAAAGTATTTTAGGCCAGGCATGGTGGTTCACACCTATAATCCCAGAACTCTGGGAGG +CTGAGGCAGGAGGATAGCTTGAGGCCTGGAGTTCAAGGCCAGCATGGGCAACAAAGCGAG +GCCCTGGCTCTACAAAAAAAATAAAAAATAAAAATTAGCCAGGCACAGTGGTGCACACCT +GTAGTTCCAGTTACTCAGGAGGCTGGGTCAGAAGGGATCACTTCAGCCCAGGAGTTCAAG +GCTAGAGTGAGCTACGATGGTGCCACCTCTTTAAAAAACAAATAAATAAAGTTTTCAAAT +GTGTGTGTTTAAGAGCAAAGAAGACAATGCAGAAGAGGAAGCACAGTGGGGATGGGGAGG +GGCGGGGCAGACCAGGGGCCAAGGAAGGTTCAGGGATGCTGTCCCTCACCCAGGGGCATT +TCAGTTCCTAAACTGAATGAAACTAGATTAAATCATGTTGGCATTCTTTTAAAAATATGT +GGCAGTTTTCAGATTAGAAACTTTGCATTAGAAACTTAGGAAATATTCCCTATGGGAATG +CCACTTCTTTTCTCCTTTATTTTCCATCCCAATGGGGGAAAAAAGACTATTATAGCACAG +TATTATAAGAAAGAAAAAAAAAAAAACTATCCTCTTTGGAGCCTCTTCTCTAGAATAAAA +AGGCATAACCTAGCAGGCATATGCAAATTATTTGGAACTAAATGTAAATACTCTTAAGTG +ATAAAATGGATTTGTATTTTTAAAGAAATCGTTTATTTGGCCCACTGACTTGCAAAGAAA +TTCTCACTTGTTAGGAACCCCTAACAGTCTACTTAGAATATTCTTCTGCCCTCTCAAAAT +AACTAAAATTGAGTTAATGTCAGCAGCCAGGACAGAAGGTTTTTGTTCTTCACACAGTGT +TTCCTTCAAATACTGAAGAGCAAGAGTGACATATAATAAGCATAAGATGTCATTCCCTCT +CTCAACCTATCTCCAAACATGTCGTCTGGATAAGCCTGTACCTGGGAAAGTCAGAATCTG +TTGAGAAGTCTCAAGAATGCCTGAATTCTCTATCACAAGGAGTCACAGACTGGATTCTAA +AATACACAAAAGAGGCTGGGCGCAGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGC +TGAGGCGGGCATCACAAGGTCAGGAGATCAAGACCATCTTGGCTAACACGGTGAAACCCC +GTCTCTACTAAAATTACAAAAAAATTAGCTGGGCGTGGTGGCGGGCACCTGTAGTCCCAG +CTACTTGGGAGGCTGAGGCAGGAGAATGGCCTGAACCCAAGAGGCGGAGCTTGCAGTGAG +CCGAGATCGCGCCACTGCGCTCCAGCCTGGGCGACAGAGACTCCATCTCAAAAAAAAAAA +AAAAAAATACACAAAAGAGCATTACTATTTTCACTTCGGTCATCTCAGTACATGGTCCTG +CCACTGTCATTGTCAGATCATGAGAACACCAGAAAATAGTGGAAAGAGAGCTTGATATTT +GTCATATACTTAATTAGATACAATAGACAGATTTTTTCATTTTAGAAATAGAGTTTGAGT +TGAAATGTTATGGTCACTCCACATACTGATGGGTGATTCCATGATTACAGGCTCAGGTAA +AAGATCTCCAGCCAGTGCTTCTCAAATAACTTTATTACATACCAGAGCCACCAGGGGAGC +CTGTGGAACTACAGATTCTGAGTTAGAAAGTCTGGGGTGGAGCCCAAGACTCTTGCTTTC +TGGACAAGCTCCAGGTGATTTCTGATGCTGCAAGTCTGGCTTTAGATAACAGCTGCTAAG +TTTGCCTGAGGATGAAAGCTTGAGTAAACTCTGAATACTGATGTTACAGGACTCCAGCAC +TTTCTAACTATATACATTTGAACATAAGAGACAGATTTTATAGCTAAAAAGGTTTGGCTT +TTTGTATATATTTCTTATTGATACAAATATGTGTACATGTATATGGGGGCACAAATATGA +TACTCTATCACATGCTTACACTGTGTAATGATCAAATTAGGGGTTTGGGGCATCTATCAC +CTCGAGTATTCGTCATTTCTGTGTGTTGGCATTATTCCAAGTCCTCTTTTCTAGCTATTT +TGAAATCTACAATACATTGTTGTTAACTATGGTCATCCTACACTGCTATCGAACATTAGA +ACTTATTCCTTCTAAGGTATGTTTGTAACCATTAACTAACCTCGTTTTATCCTCCCCCCA +CCCACTGACACATCTTCCCAGCACAGCCACTGTGAAAAACAGTATGGAGATTTCTCAAAA +CAATTAAAAACAGAATTAACATATTAATAGATCCAGCAATCCTACTACTGGGTATTTGCC +CAAATGTAAAGAAATCAGATGTCAAGGATATTTGCACGTGCGCGTTTATTGAAGCACTAT +TCACAATAGCAATGATATGGAATCAACCTATATTCATTAATAGTTGAATAAAGAAAATTG +TGGTATATATACACAATTTATTACTACTTGGCCATAAAAAAATGAATCTTGTCATTTGCA +GCAACATGGGTGGAACTAGAGGTCATTATGTTAAGTGAAATAAGCTAGGAACAGAAATAC +AACTGTCACACGTTCTCACTCAAGTGGAGCTAAAAACTGTAGATCTCGTGAAGAGAGAGT +AAAATCACAAATTCCGTGTTATACACATTCTACCACAATTTAAAAAAAAAAAAAGATCAC +ATAATTATAAGAGGTGAGATTGTCACTCACACTTTAAATTACTGCCAGAGGCTGGGAAGA +GGAGGAGTTGAGCAGGGGTGGGGGTAGGAATAAAGGATGGAATAAAGGTGGAAGGGGGAA +TAAAGAATATATTTATTACCAAGGAAGTGTACATTTCAAATGGTACAGATGGTAAATTAT +ATACATATATTTTGTCTCAATTAAAAAATATAAAAACTATAAAAAATTAAATGTTAAAAA +TAAAAGATTTTGTTTTTTGTTTTTCTGAGACCCTAACAGTTCACAAAGCAGGCAAGTTCA +GATAGGACAAAACCGGCTGTGTCACAACAGGGTGTGCACATGCTTGGTCTTTTCAACGGG +ATAATTATTTCGACTCTGGAATAATAATAATAATAATAAACAGAGTCCAGAATAATGGCT +CAGTAATAAGAGAATGAAAGCAGGCCATTCTTACTAAAAGTATTAACAATGTATTTGAGA +GTACAGTGGTCTCTATGGTGAGATTACTGGAAGATTAAAGAGGTGTCATCCAAGCTAAAT +GTTTCCAATTTGCTGAATGAGTTTAAAGACAGCTCTACAGGGGTGCATAAACACAAGCGA +CTGTCACAACCCTAAAAGGAATAAATGAACTGGTGGACTACATTTTAATGTGGAAAAAAC +TTCCACAATGCTTACACAGCTATTCCTGGCAATGAGAGGCTCATATGAAACACTTTTCCT +TAAGGGAATGGGAGTTTCTAGAGAACAGTAGGCACTTATTTAAAATTAATATTGGACCAC +AAACTTCTATCATCAGCAAGCTGAGACCTAACAAACAAGATCAAAATACCAAGTCATACA +TTTAGGCAGTTAAACTTGCTTTTAAACTGTAATAAGCTAATTAGATGCATTCAGTGGGTC +AACCATTAAAAAAAATATACACTGCACAAATCTTGTCAATTTTTCATTAAATTTTATTAA +GAAACAAGAGTCCTGTGCCAAAAGTGATAGCTTCACCATCTGAACCTGCTACTCTGGTTA +AGAAATGACATTTCCAATTCCAAATTTCACATACTTTCCTTTATAAAGACAATAGCAGAA +GACCAATGCTACATGTAAACTCAATAGTAGCCCATTATCTTGAAACCAAATCAGTGTGTG +GAAAGCTTCAAAACTTTCTTTGCCTTTTGGCACAAGACTGAAGACATGAGATTTTTTTTA +ACATCTGACCATAATAACTGCTGTATTAATCACTGTGAAGGCTCCTTGTTGACTTTTCTC +AGAGTTTTATAAAACATCGCTATCAAACAGGTATTTATCAAAATAGGCATATAATTTTAT +TTATTCCAGGAAGCTCTCTCAGTGTTAAAAGGATAAGATAATTAACGTTTAGATGGAAAG +AGAGCATGGGATGGAAAAATGCTCTCCTGAAACACAGCCAGATCTATGAAACCATACAAT +TACTGTCATGTCATCTCTGAAAGATCAAGTTAACAATGTGTATGATTTAATAATCTTACT +TAATATGGCCAGGAATGCTAACAAATCGCCAAGCCAATTTGTTCTTATTCTTACGCAGGT +AGCTAGACTACACCTCCCAGGCTCCTTTGCAGTTAGATGTGGCCATGTGACTAAGTTCTA +GACAAAAGAAAATTTTATATATATATATATATATATATATATATATATATATATATATAT +ATATATATATGTATGTATATATAACATGAGGGAGACATAAAGATTGTTGCCAATAGCCAC +TGAGATTTTGGGAGTTACTGATGGAAACATATTGCCAAATATAGCTTCAGATGTATTTCT +TCAAATTCCTCTTTTAAAATGATCATATCCCCAGGTAAGAGTTTTGGAAACAGATAGTGG +TGATGGTTACACAATGATGTGAATATGATGAATACAACTGAACTGTATACTTAAAAATGG +TTAAAATCACAAATTATATCTTATATACACATATTCTACCATAATTTAAAAAAAAAATGA +TCACTTAATTATAAGAGTTGAAATAAGTTGGAACCATGATTAAGAAGTATTTTAAATACT +CTTTCCTGAAAATATAAGCAAGACCTTTGTGTCCAGACTTGTTCAGAAAATGCTCTAAGT +GAAGAAGAGGAAGCCCTGGGAGAGGCAGGCCTGGTTAGGTTGTCACAATAAGGAGGGTAA +TTGTCAGCAGGAGGAGAGATGCTGGGACCAAGAATATATCACAGATCCTTCAATTGCACT +CCCAGGTATTTACCCAAATGAGCTGAAAACTTATGACCACACAAAACCCTGTAGTGAATG +GTCATAGTGGCTTTATTCATGATCACCAAAAACAAGAAACCACCAAGATGTCATTCAGTA +GGTGAATGGATAATAAACTGTGGTACATCCAGACAGTGGAATATTATTCAGCACTAAAAA +GAAATGAACTAGCAAGCTGTGAAAAAACACAAAGAAACTTTAAATGCATATTATTGACAA +AAGCCAATCTGAAAAGCCAAAATACTGTAAGATCTCAACTATGTGACATTCTGGAAAAGA +CAAAATTATGGAGACAGTAAAAAGATCAATGGTTACCAAGGGCTGAGGGGGAGGCAAGCA +GGAATGACTAGGTTGGGGTGCTGGTGATTTTTAGGGCAGTGAAAGTATTCTGTATGATAC +TGCAATGGTGGCTACATATTATGCATCTGTCAAAATCCATTGAACTGGACAACACTAATA +AAAACTACAGACTTTAGTTAATAATAATGTCTCAGCATTAACCAAATGTAACAAATGTAC +CATATGAATTTAAGGTGTTAATAATAAGGGAAACTAGGGGCGTGAAGGAACTCTGCACTA +CTTGTTCAATTTTCTGTAAACCCAAAACTGCCCTAAAATACAAAGACTAGGCCGGGTGCG +GTGGCTCATGCCTGTAATCCAAGCACTTGGGAGGCCAAGGTGGGAGGATCATGAGGTCAA +AAGATCGAGACCATCCTGGCCAACATGGTGAAACTCCGTCTGTCTCCACTAAAAATACAA +AAATTAGCTGAGTGTAGCGGCATGCGCCCGTGGTCCCAGCTACTCAGGAGGCTGAGGCAG +GAGAATCGCTTGAACCCAGGAGGCGGAGGTTTCAGTGAGCTGAGATCGCGACACTGCACT +CCAGCCTGGCAACAGAGTGAGACTCCATCTCTACATACATACATACATACATACTATCGG +CCAGGCACAGTGGCTCACGCCTCCAAGCCCAACACTTTGGGAGGCCAAAGCAGGCATATT +GCTTGAGCTCAGGAATTTGAGGCCAGCCTGGGTAACATGACAAAAACCCGTCTCTATGAA +AAATACAAAAATTAGTTGGGCATGGTGGTGTGCACCTGCAGTCCCACCTGCTGAAGAGGT +TGAAGTGGGAGGATTGTTTAAGCCCAGGTGGTCAAGGCTGCAGTGAGCCATGATTGTGCC +AATGTACTCCAGCCTGAGTGACAAGAGCAAGAACTTGTCTCAAAATAAATAAAGACTATC +AAACACACACACACAAACACACACACACACACACACACACACAAACTTCTCCTAGTCTGC +CTGGGGTAAAATACTCAAGCACCAAAACTCATCTGCTTGGACTATGGTCAAGGCTTCCTA +AGTATCTGAAGTAGCACCAAAGAAAGCATGTTTACATGTACAGGCATACTCCTGTTTTAC +TGCACTCCACTTCATTGCACTTCACAGTATGTTTTTTACAAACTGAAGGTTTATGGCAAC +ACTGTGTCCAGAAAGTCTATCTATTAGTGCCATTATTCCAGCAGCACATGCTCACTTTGT +GTCTCTGCATCACATTTTGCTAATTCTCTCATTATTTCAAACTTTTTCATTATTATTATA +TCTGTTATGGTCATCTGTGATCAGTGACCTTTGATGTTACTATTGTAATTGTTTTGGGAT +GCCACAAACGACACCCATACAGGATGGCAAACTCAATCGATAAATGTTTGTGCTCTGACT +GTTCCACAAACTGGCCATTCTCTCATCTCTCTCCCTCTCCTCAGGCCTCCCTATTTGATG +AGACACAACAATATGGAAATTAGGCCAATTAATGTCCCTACGATGGCCTCTAGGTGTTCA +AATGACAGGAAGAGTAGCACATCTTTCACTTTAAATCAAAAGCTAGAAATGATTAAGCTT +AGCGAGAAAGGCATGTCAATAGTCTCTGTAGGCCAAAAACCAGACCGCCTGCACCTGCCA +GGTTTTGAATGCAAAGAAAAAGTTCTTGAAGCTTCGAAATTACAAGTGCTACTCCAGTGA +ACACATGAATGATAAGAGGGCAAAAACAGCCTTATTGCTGATATGGACAAAGTTTGAATG +CTCTGGATAGAAGTTCAAACCAGCTCAACACTCCCTCAAGCCAAAGCCTAATCCAGGGCA +AGGTCCTACCTCTCTTCAATTCTATGAAGGCTAAGAAAGGTGAGGAAGCTGCAGAAGAAG +TCTGAAGCTAGCAGAGGTTGGTTCATGAGGATTAAGGAAAGAAGCCATCTCCATAACATA +AATGTATAAGGTGAAGCAGCAAGTGCTGATAGGGAAGCTGCAGCAAACTATCCAAAAGAT +CTAGCTAAGATAATTTATGAAGGTAGCTGATATGGTTTAGATCTGTGTTCCCATCCAAAT +CTCATGTCAAATTGTAATCCCCAGTGTTGGAGGAGGGGCCTGCTGGGAGGTGATTAGATC +ATAGGGGCAGATTTCTCCCTTGCTGTTCTCACAATAGTGAGTTCTCAAGAGATCTGATTG +TTTAAAAGTGTGTAACACCTCCCCACTTTGCTCTCTTCCTCCTGTTCCACCCATCTAAGA +CGTCCCTGCTTCCCCTTTGCCTTCCACCATGATTCTAAGTTTCCTGAGGCCTCCCCAGCC +ATACTTCCTGTACGGTCTGTGAAACTGTGAGCCAATTAAACCTTTTCTTTATAAATTACC +CAGTCTCAGGTAGCTCTTTACAGCAATGCAAGAACAAACTAAAACGGTAGCTACACTAAA +CAACAGATTGTCTATGTAAATGAAACAGCCTTTTATTGGAAGAAAATGCCCTCTAGAACT +TGCAAAGTTAGAGAGGAGAAGTCAATGCCTGGCTTCAATGCTTCAATGGACAGGCTGACT +CTCTTCTTAGGAGCTAATGTAGCCAGTGACCTTAAGTTGAATCCAATGCTCATTATCATT +TCAAAAGTTCTAAAGCCCTTAAGAATGATGCTAAATAAATCTACTCTGCCTGTGCTCTAG +AAATGGAATAACAACGCCTGGATGACAGCCCATCTGTTTATAATATGGTTTACTGAATAT +TTTCAGCCCACTGTTGAGAGCTACTGCTCAGATAAAGATTTCTTTTCCAAATATTACTGC +TCATTTACAATGCACCTAGTCATCAAGAGCTCCGATGGAGATGTACAAGGAGATGAATGT +TGTTTTCATGCCTGCTAATACAACATACATTCTGCATACCATGGATCAATGAGTAATTCC +TATTTTCAAGTCTTATTATTTAAGAAATCCATTTTGTAAGGCTACTGTGGCCAATCTGCC +AGAGATTGCTCGGGTGGGTCTGGGCAAAGTACATTAAAAACCTTCTGGAAAGGATTCACC +ATTCTAGATGCCATTAAGAAAGTTCATGTTTCATGGGAGGAGGTTAAAACATAGCATAAC +AGGAGTTTGGAAGAGGGTGATTCCAGCCTTCATGGATTACTCTGAGAGGCTTAAGACTTC +AGTGGAGGAAATAACTGCAGATGTGGCAGAAATAGCAAGGGAACTATTACAGAATTACAA +GTGGAGCCTGGATATGTGATTGAATAGCTGCAATCTCATGATAACACTTGAAGGGATAAG +GAGTTGCTTCTTATAGATGAGCAAAGATGAAATCTACTCCTGGTGAAGATGCCGTAAACA +CTGTTGAAATAACAACAAAGAATTTAGAATATTACATAAACTTAGTTGATAAAGCAGCAG +CAGGGTTTGAGAGTTTTGACTCCAGTTTTGAAAGAAGTTCTACTGTGGGTAAAATGCTAT +CAAACAGCATTGTATGCTACAGAGAAATTTTTTTGTGAAAGGAAGAGCCCATCAATTGCC +ACGGCCAGCTCAACCTTCAGCAGCTACCTCCCTGATCAGTCAGCAGCCATTCTCATTGAG +GCAAGACCCTCCAGCAACAAAAAACATTAGGACTCACTGAAGACTCACTGACCGTTAGCA +TTTCTTGGCAATAAAGTATTTTTAAACTGAGGTAAGTGCACAATTTTGTTTTGTTTTGTT +TTGTTTTGGGGGCGAGGGTATATACACAATTTTTTAGACATAATGCCTATTGTGCATTTA +AAAGACTACAGTATAGTGTAAACATAACTCTTACATACACTGGGAAACCAAAAAATGTGT +GTGAGTCGCTTTATTGCTATATTTGCTTTAATTATGGCTGTCTGGAATCAAACCCACAAT +ATCTCCCAAGGTATTCCAGCAGTTCCAATGGAAAGGCTAAGCTCATAATAAAGGAAATAA +CGGCCCTATTATAATATCAAATGCCATTATTAATGCAAAGTAGACAATCGCCTGACCAAC +TGTAGCTAAATTCTTGGCATTTATGAAAAAACAAACAAACAAACAAAAAACACAATGTTT +TGAATATCTGGCCAAGCTAGAGATGCTGCAAATGATGGGAGGGTATTACCATCTGCAAAG +AACCTTCCACCACAGGTGAGGGAGGTTCACAAAACTGGATGGTGGTCTAACATCTTTTTT +TTTTTTTTTTTTTGAGATGAAGTCTCGCTCTGTCACCCAGGCTGAAGTGCAGTGGTGTGA +TCTCGGCTCACTGCAACCTCCGCCTCCCAGGTTCAAGTGATTCTCCTGCCTCAGCCTCCT +GAGTAGCTGGGACTACAGGAGCGTGACACCACGCCCAGCTAATTTTTGTATTTTTAGTAG +AGACGGGGTTTTACCATGTTGGCCAGGCTGGTCTTGAACACCTGACCTCAAGTGATCCAC +CCACCTCAGCCTCCCAAAGTGCTGGGATTACAGGCGTAAGCCAGCGCGCCCAGCTGGTCT +AACATCTTTTTAAAATGAAACAGAAACAGATATCTATTGAATGCAGAAGTAGAACAAGTT +TAAGGCCTACATTTAATTCTTAAAGTCTCTTTTCTTGGCAAATATTTGGTGAAAACAGCC +TATCAAGATGACAAACCTATTATGGCCCAATGATACAACAAATACTGGCAGCCCTAGTTC +CTTTCTGTGGATTTCTAAGAAGGCAGGCATGGGCCCCAGCATCTTCTCTAAGTAGTGTTC +TAAACATTTAACCTGCATGTTTATCAAAACACGCAATTTTAAATTTAGATTCTTGATAAA +GAGGATTTGATTTAGAAAGATAATCCTCTGGGGAAATCTCGCCTCCAAATTTTAAGAACT +GAAAATCAAAGGGCACAAATTGCAGAAGGGGGCAAAGTGACACACAGAAACAAGCTCTGA +AATAAACCAAAGTAATATCTTAGTGTGAAGATGATTGCTTTAAATAAGCTGATCCAAGCC +CTAATTATTTTCTCTGGCAATTTCTTACTCTTAAACAAAAACAGAAACACTATTCATACT +CCCCTTTACAGATTGTACTCTGCTGCTTATGAACAAGCAGACAAAGAGAAGCAAAAAGGC +AACAGCACCTTCAGCATTTCTCTCTAAAAACCAATTGTTTTCGGAACAGAAACTAGAATC +TGCCTCACTGAAAAACCCTACCTGAAACCAGGTTCATACTGGCTGCTGGATAAAGGACTT +TTCAGCAGGTGGCATCTCAGAAATTACTTACTAAGTCAGCTCTTTCCAGTCACCTAGCTA +GCCAAAGTTTATTAGGTCATTTGTACAGTCAGGGTTCTCATATCTCACAATTATGGAGGC +TAAGTAAGAGGTCCCAAGACCTGCAGTTAGTAAGCTGGAGACCCAGAAGAAACTGTGGCA +TTAGATTCTAGTTCAAGCCTGGGTCCAAAGGCAGGAGAAGACCAATGTCCCAGCTGGAAG +ACAGTCAGAGAGAGGTTCCCTCTTTCCCAGCCATTTTGTTCCAATCAGGCCTTCAATGAT +AGGATGAGGCCCATCCACATTCGGAGAAGTCAATCTGCTTTACTCAGTCTACCAATTCAA +ATGTTGATTTCATCCAAAAACAGCCTCAGACACACCCAAAATATTTGACCAAATGTCTGG +GCACCCCATGGCACAGTCAAGTCCACACATACATTTAACCGTTACATCATTCCTGAGCTC +AGAGTGTTGCCATACCAAGTGTTACAGTGAGATATTTACTATTGAACGTATTAGCAGCAG +GGACCCAGACAACAACATATTTAAAAGAGAAGAAAAGATGTATGGGAAGAGAAATAATGT +AGATAACAGATAAACATAATAAAGAATTAAGGCCGGGCGCGGTGGCTCACGCCTGTAATC +CCAGCACTTTGGGAGGCTGAGGCGGGCAGATCGCCTGAGGTTAGGAGTTCGAGACCAGCC +TGACCAACATGGTGAAACCCCGTCTCTACTAAAAATACAAAAATTAGCCAGATGTGGTGG +CACATGCCTATAATCCCAGCTACCCGGGAGGCTGAGGCAGGAGAATCACTGGAACCCGGG +AGGTGGAGGTTGCAGTGAGCTGAAACGGCAACACTACAATCCAGCCTGGGCGACAGAGTG +AGACTCCCAGCTCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAGAATTAAGCAACTGTGTT +AATCTGTTTGCATTATTAAAAAGCAATAACTGAGAGTGGGTAATTTATAAAGAAAATAGG +TTTATATTTGGCTCATGGTTCTGCAGGCTGTACAGAAGCATGGCACCAGCATCTGCTTCT +GTGAGGGTCGCAGGAAGCTTCCACTCATAGTGGAAGGTGAAGGGAAGGCAGGCGCATCAC +ATGGTGAGAGAAGGAACAAGAGAGGGACCAGGTTCTTTGAAACAGCCAGCTCTCGTGTGA +ACCAACCGGGTGAGAACTTGATCATTACCAAGGGGAGGGCACAAAGTCATTCATGAAGGA +TCCCCCCCATGACCCAAACACCTCCCATGAGGCCACACTTCCAACACCGGGGAGTATCAC +ATTCCAACATGAGATTTGGAGGGAACAAACACCCAAACCGTGTCAGCAGCCAAGTGAAAT +TGTGTGTGTGAGAGAGAGGCAAAGAGAAAGAGAAACAGAGGAGGAAGGCAGACAGAGAAA +GAGAGTGCATGCAACTAAGCCTGTGTGCACACACTGAGGGGCTCCAGGGCATTGGGAATG +AAGGAGTACAACTCGACTCACAATAGGAATTGCAGCATGTCCTAGTTATCTAAAACAAAT +TACTCCAAAACTCAGCAGCTTAAAACATTGAACATTTACCATCTCACAGATTCTGAAGGT +CAGGCATGAGGGAGCAGCTTAGCTGAGTGGTTCTGGCTCCGGATTTCCCCTGGGGTTGCA +GGCAAGCCCTCAGGCAGGGTTGTAATCTCCAAAGGCTTGCTTCCAAGCTCACTCACTTTC +AAGCTCATTCACGTAGCTACTGAGGAGCCTTTTTCTCCTCTCGATGTTGACCTCTTTATG +GACCTGATCACTACATGTCAGCTGGTTTTCCAGAGAAAGTGGTTGACAGAGAAAGAGACC +CCTAGATGGAAGCCACTGTCCTTTATCTTAGAAGTGACATATCATTTCTGCTATATTCTA +CTGGTCACACAGACTAAACCTGGTAACATGTGGGAGGCAACTACACGAGTGTGAAGACCA +GATCATCACAAACCATGCTGGAGGCTGGCTACAGAGGGTAGCAGAAAAATACCTCGCAAA +TAGAAAAGGCCTTTTAGAACATCGTGTTGTGATATTGCAAAATATATATTTGGTCTGTCC +CCGTTTCCTGACATAGAGCTCCTAAAATCTTTGGAATCTCCAGAGTGATCAGAGTGTCTT +TGCGTATTAATGAGATAATTAGTAGCTGGGGGTTCCTAGATAGCCTCAAGATGGGGTCTG +GTGGCCAGGGGAACCAACCATGTGATTAGAGGGCCGGAAATTTCAGTCCCACTCCCAACT +TGTTGGGAGGGGAGAGGGGCTTACAGTTGAATCGATTAACCAACAGCCAATGATTTAATC +AACCATGCCTATGTAATAAAGTTTCCACAAACAAACAACAACAACAACAAAACAGTTCTG +GGAGCTTCCAGATGGCTGAACCCATGGACGTTCCTGGAGAACGGCATGCTCAAAGGAGAC +ATGGAAGCTCCATGCCCCTTCTCCCACACCTCGCCCTATGCACCTCTTCCATCAAACTGT +GCATATTTATCCTCTGGCATATCCTTTTTAATAAATGGGTAAATATCAGAAAAGTGTTTC +CCTGAGTTCTGTGAACCACTCTCCAGCAAACTGATCAAACCCAAGGAGGTGAGTCATGGA +AACCCCAATTTACAGGCAATGTTAAAAAAAAATTCTGATTGAGTCTGACTGACTAGCTCT +GTCACTTTAAATTCGTGTGTGAACAAACCAAAGCCCAATGTAAACAGTAAACTGAAACTA +GAAACTGCACCAATCAGAAATCACCAACTAACCTCTAACTAGAAACTTTCCACTCTAACC +AATCAAAATTGGTTTCATTTGTGTTGCTTCTGCAAATACTTTATAAAAGTTTCCCCTCTT +GCCCCTGTGGGCAGAGTGCTAGCCCCTTGTGGTCTGATGCTACCCCATTCACAAACTGCT +GAATGCTCAACTAAACTGCTGAAAATGTAAATGTGCTTAAGATTTTCTTTTATCAGATCT +GATATCAGAAGTGGGATCCAATGGACACTACATGATAATGACCTCTGGGAGCAACAAGCA +AACAGATACAGTTACCCCACAGAGCCCCTTGTGCTTACTCCCTGCACATTTGGAGGTCAT +CACCAGTAAGTAGACTTAGATACGTGCATTCTAACACTAGCGTCAAGTTCTCCAAGTTCA +TTTTAACATTTCTGCTCCAGACTAGGTTTGGAAGTCACAGCAGAAACAAGACTGGGTTTT +GCAGGGAGGCTTCAGGTGTCCAACTAGGTTAGACAAAAACCAAACTGGGTTAAGCAAAAG +ACCTCCACTAGGAAAGGTTCCACGAAGACTGGAAATAATGAGTTTATTTAAATCCAGAGT +CTGGGACTCCATCTATAGTGTGACTGGTCCCCTACCAGGTTACTTAAGAGTGTATGTGTA +TTGCTTGAACCCCAAAAGCTAGGCAGTGAACCAAGGCCACTGCGCCCAGCCAAGGACCAC +GTGTCCCTGAGAACCTAAACATCCTGGGGCATAGCTGGGGACATATCAAGGAAAACCACA +CAAAATTGACAAAGGGCCAGAAAATTAACTTAAAAGCAGCTTAGAAATGGGAGGTGGTGT +GGATCTCTAGAGCTGTCCAGCCACCATCCAGGAGTGTCCTGAAGTTAAGTCCTAACAAGC +TCATCTAGCCGTCAAGCTAGATTTATCCAAGTTATTCTTTGGTCTCCCAGCTCCTTCCCA +GTTTGGGGGTGTGGGGAGAAGGATGTTATAGTCTCAAGTGCTTCTCATAATAGCATCTCA +GAACCTAAGCTCTTCTAAAAGAATGGGCAAATCTTACCAAAAGCAATTTAGAATTTTAGT +GGCTACAAAGTGGAAGTTTTTACCTAAACAAAATTGTTCACCTACATACACACGTACACA +CACGATCTTGAACATCTCAGAAAGTGGGAAGGGCCAAGCACGGTGGCTCACACCTGTAAT +TTCAGCACTCTGGGAGGCTGAGGAGTTTGAGATCAGCCGGGGGAACAGAGCAAGACCCCA +TCTCTATTTAAAAAAAAAAAAACAACAACAAAAAAAACAGAAATGAGAAGTATTTTTTAC +TGGCATGTAGAGGTTTCTAACCTCTCGTCTACTCTGAGTCTGCTGATTTTTTTTTTTTTT +GCTTGTTTATCTGCATGCCCTGAAGGAAAAAGAACTAAATGAGTATTTATAGTTAGGTTC +TCAGATTAACCAGGTCTGCTTCTTTTTAATAGAACATTTTTAGGCTGGGCGTGCTGACTC +ACACCTGTAATCCCAGCATTTTGGAAGGCCAAGGGAGGCATATCACTTCAGCTCAGGAGC +TCAAGACCAGCCTGGGCAACGTGGCGAAACCCCATCTCCACTAAAAATACAAAAATTAGC +CAGACATGAGGGCGCACACCTGTAATCCCAGCTACTTGGGTGGCTGAGGTAGGAGAATCA +CTTGAACCTGGGAGGCTGAGGCTGCAGTGAGCTGAGATGTGCCACTGCACTCCAGCCTGG +GCAACAGAGTAAGATACTGTCTCAAAAAAATAAAAAATAAGAAAAATTTTTTAAAAGAAA +ATTTTTTACTTAATTCATTTCTTTTTGTGATAGGGTCTCCCTCTGTCACCTAGACTGGAG +TGCAGAGGCATGAACACAGCTCACTGTAGACTCAACCTAAGGGAAGAGACCACCCCTCAT +ATTGTCTTATGCCCAATTTCTGCCTCCAAAGAAAGAAGTAAAAACTAAAAGGCAGAAATG +AAATCCACAGGCAGACAGCCCAGCACCACACCCTGGGCCTGGTAGTTAAAGATCCACCCC +TGACCTAATCGGTTATGTTATCTATAGATTACAGACATTGTATGGAAAAGCACTGTGAAA +ATCCCTGTCCTGTTCTGTTCTGTTCCTTTCTAATTACCGGTACATGCAGCCCCCAGTCAT +GTACCCCCTGCTTGCTCAATCGATCACGACCCTCTCATGTGGACCCCCTTAGAGTTGTAA +GCCCTTAAGAGGGACAGGAATTGCTCACTTGGGGAGCTCGGTTTTTGAGCCATGAGTCTT +GCTGATGCTCTCAGCCGAATAAAGCCCTTCCTTCTTTAACTCAGTGTCTGAGGGGTTTTG +TCTGCGGCTCGTCCTGCTACAAACCTTCTGGACTTAAGCAATCCTCCCGTCTCAACCTCC +CAAAATGCTAGGATTACACCCATCCCAGGTCTGCTTTTTTTTTTTTTTTTTTTTGAGATG +GAGTCTGGCTCCGTCACCCAGGCTGGAGTGCAGCGGTGCAATCTTGGCTCAATGCAACCT +CTGCCTCCCGGATTTAAGCAATTCCCCAGCTTCAGCCTCCCAAGTAGCTGGGATTATAGG +TGCTCACCACCACGCCCAGCTAACTTTTGTATTTTTAGTAGAGGTGGGGTTTCGCCATGT +ACCCTTATGTCTTGATCAAAATCTTAATCTCAGAGCAATAATAAAAGGTATCCCTGTCTG +GCAGAGAAAATGCTTTGTCTGCCCTATTCATGAATGGGTTTTGCTCTGAACTTGGCAACC +TAGGTAAACATGGATTTTTTTCCTATTTTTTTGTGGGTTTTTAGATTTTTCTAGCTTTTT +TGGGTACAAAGTAGGTATATATATTTATGGGGTACATGAGATGTTTTGATACAGGCATGC +AATGCATAATAATCACATCATGAAGAATGGGGTGTCCATCCCCTCAAGCATTTATCCTTT +GTATAACACAAAGGACAATCCAATTATATTCTTAGTTATTTTTAAATGTACAATTAAGTT +ATCGTTGACTGTAGTCACCCTGTTGTGCTATCAAACAGTAGGTTTATTGTTGTTGTTGTT +GTGGTTGTTGTTGTTATTTTGAGACAGAGTCTTGCTCTGTCACCAGGCTGGAGTGCAGTG +GTGCGATCTTGGCTCACTGCAGGCTCCGCCTCCCGGGTTCACGCCATTCTCCTGCCTCAG +CCTCCAGAGTAGCTGAGACTACAGGTGCACGCCACCACACCCGGCTAATTTTTTGTAGTT +TTAGTAGAGAGGGGGTTTCACCGTGTTAGCCAGGATGGTCTTGATCTCCTGACCTCATGA +CCCACCCGCTTCGGCCTCCCAAAGTGCTGGGATTACAGACATGAGCCACTGTGTCCAGCC +TCAAATAGTAGGTCTTACTCGTTCTATTTTTTTTTTTTTGTACCCAGTAAACTCATGTGG +ATAGGACATGAGGAAAGCCAAAATGGACGCAAAAGGCAGAAGGGTATCACTCTGAAGATG +ATATCTGTGGCCATGAGACCCAATTTGGTTCATATATAAACCACAAAAAGCAAAAAAAAA +CCCCAAAAAAACATAAATAACCTTTTTTTTTTTTGAGACGGAGTTTCGCTCTGTTGCCCA +GGCTGGAGGGCAGTGGCGTGATCTCAGCTCACTGCAAGATCTGCCTCCCGGGTTCACACC +ATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCGCCTGCCACCACACCCAGC +TAATTTTTTGTATTTTTAGTAGATACGGGGTTTCACCATGTTACCTAGAATTGTCTAGAT +CTCCTGACCTCGTGATCCGCCCACCTCAGCCTCCCAAAGTGCTGGGATTACAGGCGTGAG +CCACCATGCCCGGCCATAAATAAGCTTTTGAAAGCCATTCCTAAAGTGTTTCCCACCTGC +ACTAAACCAGACCTGCAGACAAAAGAAAAATGAATCTGTTACTAATTTCAAAGCCCACTT +GGACCTTTTGTTTTTCCTACAGCATTCCAAGCATTACATCAATTCAGCTAATCCTAGCTG +TCCTTTTTGTAAATGGAGTCTCCCCACAACATTACCAAACAAGAAAGAGAGAGAGGAAAA +GGATAAGGAAGCTACAGGGTTAAGTAAGTTAGCTGAGGACCTCAGAGCAAGATGAGAAAC +AAAAGGTTTCCAAATTAATGGCCTTGTAATTATAGCAACTGCGGAGCAACCAACAACCAA +GAAGGACCTTTGGACTACTTTTAATAAGTGACTCAAACCAGACGTTATCTCCTTCTGTCT +GTCTTTGTATGAATGTTTGTGTGTGTGTGTGTCTATATATATACACACACATATGTGATA +TTTTCAGATGGTATTACTAAACCAATTTATAAAATCCTTTAATGGAGATCTATTCAAATT +GGTTTGGGGATAAATGAGCATGCATGTAAATTATTTCTAAAACTCTCAGAAATGCAGAAA +CTGACCCAAATGTGTGTTTTTTTTTTAATAAGTTCACATGATTTACATAAGTCTGTGGTA +AATAAAGCTAGTTTTTAAATTGTCGGTAAAATAAAATGGGAGTTTCTCAGAATTCTCAAG +TTTTTCCTGGGTTGCTGGTTAGACAGATTGGTGTTGGCTCTGCTAGATGTTTAAGATCAT +AAAACCATAAATCCAACCTAAGAGGAAAATGTGCAGTAAAAATGAATTGCTTGATCTTGA +TGCACGTCAGTCATGGAAGTAAAAAACTGTGATACCTGCCTGATTTGTCAAGAAAAATTA +AATAACATTAAGATGATGGCGTGGGAGAAGGCATGGATGATAGCTGAATTTCTTTGGAGG +ACCTGTCTTTAGGCAGACAAAGGAGTCCCAAAAAGCCCCTCCCTGCATTTGTTATTTTTC +AAATGCTTTCGGCTCAAAGCAATCAATATTCCAAAGCAGTAAATTTTGGAGTGGCATTTC +CTGAACTCTTTCAATGGCTAACTCTGTTCAATATCTCATGACATTTTTCATGAGCAATTC +AAGTATATTTGTTTAAGAAGGAGTGACTTAAATATAAATGGAATAAAAGTTTAAAACTTT +TTGAAATTATGTTTTATAAAATGTCTACAGTCATAATCTTGATTATTATGTTAAAATGTT +GTATGTCACAGAAAATAACCAGATTTTTTTGTCAGTTGCATTATTATAATGAAACCTCAT +TAGAATTTAACTATGGCCATCTTAAGTCTTGTCATCCATAGGCAGTTATTGTTTTGATTT +TTCTCTAAAAGCATTTGCAATCAGCTATAGTCCAAAATTGCTTCTTCTTCAAAGATATTC +ACGGAAAGAACTCTGACAAGTACTCTGGATATACAGGTTTCTTATAACTTTAAATTAAGA +TAATGCCATGAAAGTGGGTAAGAATTCTCAGAACGCTAATAAAGAAACTGGTGAGTTTGT +GAAACTGCTATCCCGAGATCATGCAGAACAAGAATTACATAAGACTGAATAACTGATGAA +AATAATGTTTTTATGACTTTATATGTGGAAGTTTTGCTGGTTCTTTAAAGTTTTAAGAAA +CATTTTACCTTTTAAGCTATCTACTGCTTGCAGCAATTTGGAAAAGTATACTTTTGTGAA +TAAAGATTGAAGTATTTACTTTTCCTCTCTACCTGATCCTCGGGAACTTGGAAAGCTACT +TGTGAAGATTTTTTTTATGGCAATATAACTATTTGCATAAGTTCAAAAAGAATCTGTTCT +CTTTATAACAAGACACAATTGGAAACATTGGTTATATTACCAAGGGTCATATTTGACAGT +GTGCATAGAATGCCTGGCTAAAAGTGTTCCCAGTCTCACAGTGAGTGAGTAAAAGCTATC +AGTTCCCAGCAGACCCAGGAACCTCAAGATATTTGGGGGACCTTACGAGAAGAGAAGAAT +TCACCCAAATATATAGGTACTGCAGGTGAAGTCTAAAATTTGCCTTGGTTTGGCTTCCTA +GATTTAAGAGGTTTTTTTAAAAGTTCAATCTGATTCCCTATCAAAGGTTCCAGCAAAACA +AACTTTAAAAAGAACTTGTGCGGTCAATCACTATTCTTACTGCACTTACATAATCAGGCC +AAGTCTGATGAGACAAAATTTATTATGCAATCAAATTAGTCTTACACTGATTATTATTAT +TATTTTTGGAGACGAAGTCTCAAGCTTGTCCCCCAAGCTGGAGTGCAATGGTGCAATCTC +GGCTCACTGCAACCTCCGCCTCCCAGGTTCAAGCGATTCTCCTGCCTCAACCTCCTGAGT +AGCTGGGATTACAGGCACCTGCCACCATGCCTGGCTAATTTTTGTATTTTTAGTAGAGAC +AGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAACTCCTGACCTCAGGTGATCCACCCGC +CTTGGCCTCCCAAAGTGCTGGGATGACAGGTGTGAGCCACCGCGCCTGGCCCATTTATCT +TTGGTAGAAACAAGGATGACTACAGAGAGAAAATTATGTTTCAGAAAGAAACAATAGTAC +ACCTGTTATTAGACTGCAGCCCTATTAACTGTTTTCAAGTTTTATTATCTACCTGTAGTT +TGCACTGAATCCTCAGTTCTTCTAGGTTCCTCCATCCAATTTTCTCCCACTTTTCTGACT +TGGAATCACTCTGAACAAGAACTGCTCTGCTCCTGAAACCCTGCAAGATGGAGATGTATA +CCTGATACAAGTTCAGAGGACAACCCTCATGCCTGATGTGTGGACCACTCAGGGAGTTCA +CCAAAATGCCCACTGCCATAACTAGGGGCATTCAAACTGCAAACCAGGAAAATATGCTTA +GAGCTCAAATCTAGAAATCTTCCTGACTAATCACCCTCTGGACTCAGAGACCGAATTTAT +GATTTGTTCTTATCATTAAGCTTTGTTTTTCTTTTGCTTCCATAGAAATATTAGTTAGTT +TGGTTCGTGGGGACTTTAACTAAGAAGCTAAGTCTCTCAGTATTATCCTCCTGGTAGTCA +TCATTATAATCTTCCTGGTGCACTATATTCTCTCAAGGGTCTTAAATGTATATTCAAAAA +CATCAACAGCATACCAGATTGTCTCACTGTGATTAGAAAAAAAATGAGATTGACAACAAA +AGGAATTGTTTTTCATTGAGCCTGTTGTCATGATTTATGAGTTCCACACTAAGACAAAGA +CAACCTAGCCATGATGGTGACAGAGAGTGGCACTTACGTCCAAGTTTATAAATGAGAGGC +TGACCAAAAGGAGGAAACTTATATGTAACTAACCTGCACATTGTGCACATGTACCCTAAA +ACTTAAAGTATAATAATAATAAATAAATAAATAAATGAAAAAAAAAAAGGAGGAAACTTA +AAAAAAACCATTCCAATTGAGAGTCCATTAGACTAGGGTAGGGTAGCTCTTGTCACTTTA +AATCCCTAATCGAACAAACCAAAGCCCAATGTAAACAGTAAATTAAAACCAGAAACTGCA +CCAATCAGAAACTACCAACTAATCTCTAACTAGGAACTTTCCACTCTAATCAATCAAAAT +TGGTTTATTTGTCTTGCTTCTGCAAATACTTTATAAAAGCTTCCCCTCTTGCCCCTCCTG +GAGGAGTGACACTCCCTTGTGGTCTGCTGCTACCCTATCCATCAACTGCTGAATGCTCAA +GCTGTTTCGGCTGGGTGTGGGGACTCACGCCTGTAATTCCAACACTTTGGGAGGGTGAGG +TGGAAGGATCACTTGAGGCCAGGAGTTCAAGATTAGCCTGGGCAACATAGTGAGACCTTG +TCTCTAAGAAAAATAAAAACATAAAAATTAGCAGGGCATCGTGATGTGCACATGTAACCT +CAACTACTTGGGAGGCTGAGGTGGTAGTATCACTTGAGCTCAAAAGTTCGAGGCTGCAGT +GAGCTACGATATCATCACTGTACTCCAGCCTGGGCTACAGAGCAAGAGCCTGTCTCTAAA +AATAAAAATAAAAAATAAAAATAAATGGTTTAAAAGTGCTTAAGTTTTTCTTTAACCACT +GGTCAGTCAGAAATTCCATATTCTGGAGGCCCTGACTTTGATTGGCATCTGAAGTGGGGG +ACAGTCTTATGGGACTGAGCTCTCAAGCAGTGGGATCTGACACTACCTCTAGATAGAGTC +AAAATTAAATTGAATTAGAGGAGACACCAGAGCTGATGTCTGCTGCAGAACTGTTTGGTT +AGTGTGTAGGGAAAAACCCCCATGTACTGGTAACAGAAGCATTCTGTGTGGTACTGAGTG +ACTATGTTAGAATGGGAAAAGAACTTTGGTTTTTCCTATATCTCTACACTTACAAAGACA +AAATTTTTTAAGATCTTGATCATATAGAATGATGCAACTAGCTTACCATTAATAAATCAT +GCCCAGTGAGGTTTTTATCCAATAGTTGTAAAGAATTTGTACAAATGCATCTGACTATAA +AATATATATGTTTGCAAGATAAAAAGGTTGAATAACTAGAAGATGTAGAAGGAACAAGTA +CTCTTGGGTCAGGCAGAGCCAAGGATCAATGACAACTGCACAGCTCACAGGCTGTGTCAC +TTAGGGAAAGTTTTCATCAGTGTAAGCCTCAGTTTTCTCACCTGTAAAATCTGAGTGATA +TTTACTTACATCATAGGGTTGTTGTGAATGGCAACAGAATATGCTTAACATGCAATATGT +ACAGTAAACAGTGGCATTTGTTGCTAAATAAACCATTGTATGTGTGAAATCAAAACATTA +ATTGGCTCATATTCTAACTAAGTCACCATACCTGATGTGTGGACCACTCACAGAATTCAC +CATGGCTCCAGAAGTAATAACAGTTTTTCCCACAGCACAAGGACAAATAAAATACCCAGG +GTGACTGTTGAATTTGAAGATTACTTGCCTCACCTTCAGAGATTATGATTGAATACAAAC +AATTGTAGCTAACACTAAGTGTGTACCAGGTGATAAGCAGTGCTCTAGCACTTCACATAA +ATTAATCTACTTAATCCTCACAATAATTCTATGAAGTAGATATTATCATTATTCCCATTT +TACAGATGGCGAAACTGAGGCACAGAAAAGGTAAGTAAGTATCTTGCTCGAGACCACCCA +GTCAAGTAAGGGCAGATCCAGGATTTGAACCCAGACTGATTACCTTGAGCCTGTGTTCTT +GGCCACTATCTTGCTCTTCCTCCAAGATTTGGGGCAGGTCCCAGGCATCTCTATGTTTAA +CTAGTACCCCCAAGTGATTCTGGTATGAGTAGTCCATAAATAAAGAAACACTAGACTCTT +GGTAGTAAAGAATACCAATAGTTTAGAAATCGTATCTCGCAAGTCTAAAAAAACAATGTA +GAGTTTATTGGGCTAGTTAACTGCTGGACTTCTTTGCTAAGGTAGAAAAATATAAACCAA +GTGGAAAAAAATTTCACTTCCAACACTGAAGCGACTTATCAGTTCACACAAATCTTCAGT +GGTTTTCTTGCCTCCAGACTCTTCATCAGCAACCCCCCAACCCATTCAACAATATTCGAC +CTGGCTTTCTATAATATTCTCCCTAATGAACTACAGGTTGAATATCCCTTATCTGAAATG +CTTAGGGTCAGAAGTATTTCAGATTTCCGATTTTTTCAGGTTTGAAATATCTGCATATAC +CTAATGAGATATATTGGGGATGGGAACCAAGTCTAAACATAAAATTCATTTATATTTCAT +ATACACCTTATACATATAGCCTGAAGGTAAACTTATACACTATATTTAATAATTTTGTGC +ATGAAACCAAGTTTTGACGGCAACCTGTCACAAGGTCAGGTGTGGAAGTCTCCATTTGTG +GTGTCAGCTCTCAAAACCTTTTAAATTTTGGAGCATTTCAGATGTCAAATTTTCAGATTA +GGGATGCTCAACCTGCAGCAGGTTCTATCTTCTGGCACCTTTTCACTAAACCCTACCTTG +ACCACCTATTTAAAATCACATCTATGAAATGAAATATCATCTCACCCCAGTTAGAATGGC +TATTGTCAAAAAGAAAAAAAAAAAAAACAAGTGCTGGCAATGATGCAGAGAAAAGGGAAT +TCATATACACTGTTTGTGAGACTGTAAATTAGTACAGTAACTATGGAAAACAGTGTGGAG +GATTCTCAAAAAACTAAAAATAGAATGACCATATGATCTACCAACCCTACTACTATTTAT +CCAAAGGAATGGAAATCAGTATTTCAAAATGATACCTGAATCCCCATGTTTACTGCAGCA +CTATTCACAATAACTAAGATATGAAATAAACCTAAACATCCATCAAAAGATGAAGAGATG +AAGAAAATGTGGCATATACACACAATGGAATACTATGCTGCCATAAAAAAGAATGAAATC +CTGTCATTCACAGCAATATGGATGAGCCTGGAGGACATTATGATAAGCAAAACAAGTCAG +ACACAGAAAGCACCTGCTCTCATTCATATGTGGGAGCTAAAAAAAATGTGGCCTCATGGA +AGTAGAGAGTAGAAACTATAACTTATTCTATATCCTCAAAAGGCTAAAAGAGAGGATGTT +AAATGTTCACAACACAAAGAAATGATAAATGTTTGTGGTGAAGAATATGCTAATTACCCT +GATTTGATCATTACACATTGTATCCCGATATCAAAGTATCATTCTGTATCTAATAAATAT +ATACAATTATGTGTCAAGTAAAAATAAGAGGCATATATAAAATCACAGGCCGGGCATGGT +GGCTCACACCTGTGATCCCAGCACTTTGGGAAGTTGAAGCAGGCAGATCACTTGAGGCCA +GGAGTTCAAGACCAGCCTGGCCAACATGGTAAAACCCCGTCTCTACCAAAAATACAAAAA +TTAGCTGGGTGTGGCAGTATATACCTGTAGCTGCTCAGCAGGCTGAGGTGGGGGAATTGC +TTGAACCCAGGAAGTGGAGACTGCAGTGAGTGAAGATCGTGCCACTGCACTCCAGCCTGG +GCGACAGAGTGAGACTCCATCTCAAAAAATAAAATAAAATCACAACTCTGCCTTTCTCCC +TAAACCTCCACCTATACACCCATTCCCCACTACCCTACTTTTTAAATTTTTTCAACAGAA +TATATTACCTAGCATACTATATGATATACTTATTACACATAGTAATATTGACTGCCTCCT +CAACTAAAACATAAGTTTTAGAAGCAGGAATTTTTTTTCTGGTTTATTTTGCTCATTGTT +ATACCCCAAAATGCCTAGAACAGTGCCTGACACACATAAATATTTGTTGCATTAATTAGT +TAATTAATGTCATTGTCCAGCTCAAAACTTTCAATAGCTCCCCACTACTAATCAAATAAA +ATCCAAGCACGCTCTCAGGGAATCTGGACACTCCAAAATTAGGCCCTAACTGACCTTTCC +ATCCTTAATTTTTCCTAAGTCAGACTCAGAAGTCCAAGAGTTGACATTTCCTTACTTCCT +GCTTTCCTGCCCCTGTGCCTCTGTTGATGTAGCCCTTTCTGGCTGCCTTGCCTATACCAC +AATATCTTTATCTATCAACGTGATGCCTATTGTGAATGAGAAACTACTCTCCAAGGTCTC +TGAAACGGTGTCTGTTTCAAACACATCCCTGAATTCAGTGGCGTGACAGGCTCCACTCCT +AAGGCTTAGTTTCTGCCAAGTGCCATCTTCCATGCTTCCATATGTTGTGGTTAATTGTGT +CTGAGTCGTACCCCTCCACTGACGCTAGCTAACTGAGGGCCCTGATGGTCTGGGATTTGA +GGTACATCTGTACACAAAGAATAGCTGCCTATTGCGTTGCACATTTTACAAGTCAGACAA +TGGAAGGGGCCTGTTGCTTATAATGCTCCTTTTGTTTTTTGAAAATTTCTGCCACATGCA +CCTTTTTAAGCTTTTTGACTTTTTTAAACACAGAGGGCTGCCCTACATTCAACCACTTAG +GCCCACTTTTGAAGCCCAGGCCGACTGGAGAGTGCAAAGAGCAGCCAATCTGCAGACTGA +AGACAGGCTTGGCAGAAAGTCTCCGCCCGTCTACAGTGGTCTACAATGAATAAAAAACAG +TGACCTGACAAACCAATCTGATCTCTCCTCTGAACAGGAGTCTAAAATGGAGATACCAAG +AGTCAGTACTTACCAATGGGCACAGAAGCCACAATGACCTACAGAGAGATGACGAAAAGC +AGAGCAAGAGAGCAGAAGCTATAAGGCTTCAATAAACAAGAAAGATCAAGAGTCATACAA +GCGGCGGAAAAGGCAGCAGAACCATAACAGTAGAATGTCACCTAGAGAGAAGGAAGGGAG +GCAAGAGAGGAATGGAATGTCATCTCTGAACAGCCAACTACTAGATTTTCAATCAAGCTC +CCTGCAGAGGGCAGACCTTACAGACTAACTCCTGGAAGACTGCTGTATCCCCAAAACATA +AACTTAACTGTGTGGCTAGTCCTACTTTTCTTATTCTCTATGAATTCAATAAAATCCATC +ACTTGTTTCTTGAAGCCTAACAGAGCCTATTTATATGGCAGTAATACCGTGTGATACATG +GCAGTGATACCAGTCCAGAAGCCAGAACGGAAATGGAGGATAAATCTGACCACACAAAAC +TTTAAAACTTCCGTATGGCAAAAAATGTTCAACAAGGTCAAAAGAAACTATAAACAAGGA +AAAAATATTTGGAAGACATATGACAAAGGCTAATTTCTTCTTAATATAACAAAAACTTGT +TAAAATAAATAACCCAATAAAAGACAAAGAAGTAAAGGATATCATAGTATAGAAAAATAA +ATGTAAATAGTGCAAACTCTATAAAGGATAATTTGTCAATATCTACTAATATTGAACATT +ATATCCCTTTGACCTAACAAATCAACTGCTAAGAATTTACCCTCAGAAACACACTATCAC +CAAAAGTACCCTACAATATATCAAAAGATATTAACTGTGGCATTATTCATAACATTAATG +ACCATAAATAGGTTAGTTATGGAACACTATGTGGTCACTAAAAGATGAATTCAATTTTTA +CAAAAAGATCTCTAAAATATAAAGCATTAAAAAGCAAGGTAGAACTAAAATCCTGAATTA +AAACAGCAATCATTATTGCCAACCATACAGAATAAAAAGGATTATAAAGTAATACTATGA +CCAACTGTGTGCCAACAGATTGGTTAGCTTAGATGAAATGACAAATTCCTAGAAAGACAC +AAAATCCTGAAATTGACTCAAGAATAAACAGAAAATCTGAAAAGACCTCTAACAAGCAAA +GATATTCAAAAACCACCCACATGCAAAGGCCTACTCCCAGATGGCTTCACTGGTGAATTC +TACCAAATATTTAAAGAAGAATGAATACCAATTATTCACAAATACTTTCAGCATAAAATA +GAAGAGGAGGAAATGCTATGCAGCTCAGTCTATGAGGCCAGTATTACCCTGCTACCAAAA +TCGGACAAAGATATCACAAGAAAACGACAGACTAGTATTTCTAATAAATACAGACACGAA +AGTCCTCAGCATAATACTAGCAAACCATTATCTAGGAATGTTAAAAAAAAAAAAAAAGTT +TATTTAGTATGAGCAAGTAGAATTTATCCCAGGAATGTAAGTTTGTTTTAACATCCAAAA +ATCAATCAATGTAATCATATCAATAGATAAAGGACTAAAACATATGATCATCAAAATAGA +TGCAAGAGACATAGAAAAAGCATTTGACAAGATTCATCACCCTTTATGATCAAAACACTC +AACAAACTAGGAATGTAAAGGAACTTCCTCAGTTTGATAAAGGGTGTCTATGGAAAACCG +CAGCTAACATCTTAGTTAACAAAGACCGAATGTTTTTCCCCTAAGACCAGGAACAGAAAG +GGTATTTGTTCTTATCACTTCTATTTAACATTGAACTGGAGGTTCTAGCCAGGACACTTA +GGCAAGAAAAAGGACTAAAAGGCATCCGTTTTGGAAATGAAAAAGTAAAACAATTTCCAT +TTGCAGTAACATAATCTCATGTATAGAATAATAAGGAATCCATTAAAAAACTATTAGAAC +TCATAAATGAGTTCAGCAACTTTGCAGGCTTATAAGATCAATTCACAAAACTTATCACGT +ATCTATACAATTTCAATGAATAACCTAAAATTGAAATTAAGACAAAATTGTATTTACAAC +AGCATTGAAAAGAATACATTTAATAAGAGAATTTATACTTTGAAAACTACAAAATATGGC +TGAAAGAAATTAAATACATTTAAATAAATGGCAAGTCTAAAAAAATGGGAAGACATCCAT +ATTCATGGGTCTGAAGACTTAATATTGTGGAGATGACAATACCTCTCAATCAATTTACAG +ATTCAGTGTAATGCCTATCAAAATCCCAGCTGACTTCTTGACAAAAATTGACAAGCTGAT +CCTAAAATTCTCACAGAAATTCAACGGACCCAGAGTAGCCAAAACAATCTTGAAAGAGAG +AACAACTTAGAGGACTCATGCTTTCTTTTTTTTTCTTTCTTTTTTTTTTTTTTTTGAGAC +AGAGTCTTGCTCTATTGCCCAGGCTGGAGTGTAGTGGTGCAATCTTGGCTCACTGCAACC +TCCACCTCCCAGGTTCAAGCGATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAG +GCGCGTGCCACCACTCCTAGCTAATTTTTTGTATTTTTAGTAGAGATGGGGTTTCACCAT +GTTAGCCAGGATGGTCTCGATCTCCTGACCTCGTGATCCGCCCACCTCAGCCTCCCAAAG +TGCCAGGATTACAGGTGTGAGCCACCGCACCCAACCCAGACTCAAGCCTTCTAATTTCAA +ACTTCACTACAACACTACAGTAATCAAGATAATGTGTTATAGATATAAGAATAGACATAT +AGGTCAATGGAATAGAATTCAGAGTTCGGAAATAGACATTCACAGTTAAGGTTAATTGAT +TTCTGACAAGGTGCCAAGACAGTCTGACATGGAAAAATAGTCTTTTCATTAAATGGTGCT +GGGGAAAATGGATAGCCACATGCAAAAGAATAAAACTGGACCCCTACCTCAAACCATACA +CTTAGAATCAAAGACCTAAATGTAAGGGTTTAAACTATAAAACTCTTAGAGGAAAACACA +GATATAACTCTACATTGGATCATGCAATGGTTTCTTAGACAGGACACCAAAAGCACAAAA +AAAGATAGATAAATTGGACATCATCAACATTAAAATCTTTTATGCTTCAAGCACACCGTC +AACGAAGTGAAAAGACAACCCACAGAATGTGAGGAAATACTGTAAAATCATCTATCTGAT +GATGGCATTGTATCTAGAAAATAAAAAGAACTCTTGCCATTCAATAATGAAAAGACAACC +AAATTTTCAAGTGTGCAAAGAATCTGAATAAATCATTTCTCCAAAGAAGACATACACATG +GTCAATTAGCACACACAGTGATGGCCAACATCATTAGACATCAGGGAGATGCAAATCAAA +ACCACCTCATGCTTCACACCCACTAGAATGGTTATAATCAAGAAGACAATAATAAGTGTT +GGTGACGATCCAGAGAAACAACAATCTTCATACACTCCTAACAGGTATGTAACACAGTAC +AGTCACTTCAGAAAACCGTCTAGCATTTCCTCAAAAGGTTAAATATAGAAATTACTGTAT +TACCCCATAATTGCACTCCTAGGTAAATATCTAAGATAAATGAAAACAATATGTCTGTAC +AAAAAAACATGCACAAATATACACAAGTATTCAAAGTAGTTAAAAAGTAAAAACAACCCA +AATGTCCATCAACTGATGACTGAATAAATAAAATATGGTACATGTATACAAGGGAATATT +ATTCAGCAATAAGGAAATTAAGTAATGACAGATGCTACTCCATGGATGAACCCTGAAAAC +ATCATGTGACGTGAAAGAAGCCAGACACAAAAGACCACATATGTATAAACCCATTTATAT +GACATATCCAAAATAGGCAAATTTATAGACAGAAAGTAGATCAGTAATTGCCTAGGGCTG +GGAGTAAGGAAGTGGGGAGAGGAATGAGGAGTGACTGCTAATGGGTAAGGAGTATCCTTT +TGGGTTGATGTTCTAAAATTGTGGTAAATGTTGTACAAGTATCTGGATACACTAAAAACC +AATGAATTATAGATTGAATGAGCTGTATGGTTATCAGAATTATATCTTAAAGATGTTATT +TTTTTAAAAAGCAAAGCAAAGAATAATGTGTATACTATCCCATTGTAAACTTCTACCCGT +GGCTTTGTGTATGTGCTAGTACATGGACAGTTTTCTGGGGGAAAAAAAGTCAAGAAATTT +AACAGTAGTTTACTTTGGGAAGGGAAACTATAGTGAATGAGTTCAAGAAAAAGGGATTTC +AATTTTTTACTTTATACCTTGCTGTTCATGTAAAATTTGTTTCACACCATGTGAAAGAAA +ATATAAGCTTCTTTAAAATTAAAAGAATATATGGCCTTTAAAACCACACAGTACTGGCAT +AAGAATAAACAAAACATTTGAAACAAGTCCAGAAATAGATCCACAAATATAAAGGAATTT +AATGTATGAAAATACTTACATTTTATATGAGTGGAGAAAAGATAAATCTTTCCCTAATTC +AAGCCAGAAATTCCAGATGAAATAAAAAGCTATAGCAGAAAACATTAGAAAATATACACA +ATTAAAATGTTAGAAAAACTACAGGACATTAATAATTTGGGTACTGATGGGATCTCTCTG +GGATAAAAAACTCAAAAGTTACTAAGAGACTGACAAATTTGACTATATACTATTAAAACT +CTGTTATGATAGAATAGCACAAGTTAAAAGACAAGTGACAGCCTGAGAGAAAATATTTAT +AACAGACAGAGGTTTACATACCTTGTACCATGTATATATATAAGGATTCAGTAGATGGTA +TCTAAGCACAACAAAATTGGAATTAAATGAATATTTCTAAAAAAAAATAATAGGCTGGAC +GCGGTGGCTCATGCCTGTAATCCTAACACTGTGGGAGGCCGAGGCAGGTGGATCACCTGA +GGTCAGGAGTTCAGACCAGCCTAGCCAACACGGCAAAACCCTGTCTCTACTGAAACTGCA +AAAATTAGCTGGCCATGGTGGTTCACGTCTGTAATCCCAGCTACTCAGGAGGGTGAGGCA +CGAGAATCACTTGAATCCAGGAGACAGAGGTTGCAGTGAGCTGCCACGGCACTCCAGCCT +GAGCGACAGAGCAAGACTCTGTTTCAAAAAAAAGAAAAGAAAAAAAAAGAAAAGAATGGA +TGGATTGAATGACAGGTTGATCCTGTAAAAGCTATCGATGGGACTAAAACACAATATATG +CATAGAAGTGAAGTGCTGCTTTAATCTTTGAAATGGCTTGCACTTTTATCAACATTGTCA +TTTGACCTTCTTCAGTTAGCAATATAAACAGAATGTTTACTAAAATCATTTTGGCTAAAA +AATATCTAAGATAAATATTTCACACTAAGAAGGCTTTCTTCAGTTGCCTTATGTCTTATA +ACATAGAGATAATATTCATTTGTCATTTAAAACAAAAAATCAGACTGGACGGGGTGGTTC +AGGCCTGTAATCCCAGCACTTTGGGAGGCTGAAGTGAGCAGATCACCTGAGGCCAGGAGT +TCGAGACCAGCCAGGCCAAGATGGTGAAACCCCCATCTCTAATAAAATTTCAAAAAATTA +GCTGAGCATGGTGGCATGTGCCTGTAGTCCCAGCTGCTTGGGAGGCTGAGGCAGGAGGAT +AGCTTGAACCAGGGAGGCAGAGGTTGCAGTGAGCTGAGATCACGCCAGTGCACTCCAGCC +TGGGCGACAGAGTGAGACTCTGTCTCAAAAAAAAAAAAAGGAAAAAGAAAAAATCAGCCT +GAAATACAAACTTATTTATGTTGGTTTTCCCTTCTTCTACCCACAGAAATTTGTGAACAT +ATCCAAGATCATTATCAAGACGTCAAAAGTCAACACTCTAACATTTTCCACCAAGAACAA +ATAATCATGTTAACACTAAGGGTTATTTAAGGTGAACACAGCAAAACTGCTGCCCTTTCA +CAGCCCCAGCAAAGGCAAGATGTGACAGGAGCCCCCAGTAAACATGAAAGTGACAAGACC +CTTCTCCGTGCAGGATAAGAGGCCACATAATTCAATTCAATTAAAAGATTATGGCCATGG +AGACAGAATTTTCACTGAATGTTTTTATAACGAGCTCTCAGAGAGTTTTAGGGTTACTCT +TACTTAATGCAGCCATTAATCCCCATGAATACCGTACAGCAAACTAACAAATACATTGTG +TAAAAGTAGTCAAGCCCAAACAGACCATCCAAACTAATCCCCTGAAACCTCAGGAGCCAC +GTGGAAAATCTAATATAATTACCTCCCACTAAACTCTGTACATCTGTTACAGGGAGTTCC +TACTGTGATTACATTCTTAGTGCAAATGCCTGGAATTAATTCCAAAACAATCCAAGCCCA +GGCCTAACCAAGTGGCCTTCACGACGCAAAACCTGCATCGGATGGTCCTCTTTTATCTCC +TTTCATCCACAGGTAGCCTGGTTTATAAACCAGGGCTCCAGTCTGGCTTTATCCCTTTCT +TTATTCATTTACAAGGTTTTTTCATTGATTTCCAGCTGAGTTCCTACAGCTAGTAGTAAT +AAGACACAGTAAAAGGGTTTTTCAAAAATTATAATTATGTAATTAATAAAGAAATTATGT +TTATCATTATTTCTACTTCACATTTTTTTCTACTTCCCCTTTGCTTTGCTTACTTACACC +TTCAAAAGAAAAAAAAAAACTCCTGTGCAATGATGTTTTATCATTATTGTCATTTTATAG +ATGAGAAAGGTAAAATCAAATTATTTAATTTAGCTAAAATCTCACAAAAGTTCTCTCAAG +AGAACAAGGAATCAGGTCTTACTACATAAGGGCTTTCTCTATGGTGACACGTCACATCTC +AAAACAAAACAGAAAGTAAGACAAACCAAGCTGTGATGCAGGAAAACAGAGGGAACTGGA +AGTTGGATAAAGGGCAGAATGAGTAAAAGCAGAGAGCAGAAGCAAGGTGAATGGGTAGCT +GAGTAAGAAACAAGAGACAGAAGCTGAGCAGCCAAAACAAAAACAAGATTAAAAAGTGAG +TAAAGAGACCCCATAGCTGGCTCCTCAGAGATGGGCATGCGCATCAGAGAGAAAAAGTAT +CCTTAACATGACCCCATATGATAATCAGCTCATTAAAGCTCATGCATATGGACTGTATAT +TATGGGATGGAGGCAACACACAAGCACATAAGGGCCAAAGTAAGCAGTCCACCTATCAAT +TAAATGGCAGAGTCTGGCTAAAGATTAGGCAGCCTTGGGAAGAGAAGAGACAAAAAAACA +CATACAAATACCCAAAGTACATCAAACTGATGCTGATCTCATTTCACAGAGATCAGTCCA +CTCTCCTCTCTCCAAGAGTGTAATACAGTGCTTAATAAACTTTTGCTGCTTGCTTTGCTA +CTTGTGTGTGTCACGTCCAATTCTTTGTTCAGGACACCAAGAGCCTGGAACTGCACGGCA +CCATCCAGTGACAGTTGGAGTACACAGAGGGAAGAAGGTGTTCAGTCAGAAGCAGGATTC +AGGCTGAATGCATGGTAATGAACAAGGACATGGCAATTCCACAGACAATAGTTTGGGAAA +CCTTCACTGCTAGGCTGAGAATTCTGACGTCTGCCTCTAGGCCAGCAAGGGCATGCCGTG +GCAGAAGCAGGTCAGCAGTGGGGCATGGAGTAGGAAGAAAGCCGGAACTGCAAGCATGCT +CAGGAGCACTACTGAGGTCCTCTGAGCAGAAAGGCACCAGCTGACTTGAGACAAGGACAG +TGGGTGGGAGGAAAGGAGGTAAGTGCTGGTGATAAGGTAGAGAGGTGACAGTTCAGGTCT +GCATCTTAGATGAGTCTCTCTGGTGACTGTGGAGGACCAATTTGAAAGGGCCAAAAGCAG +AGGCAGGAGGGCTCTGCAGAATCTATGTGAAGATGAGGTCCTGAGCTAGGATGCTGGTGG +CTTAGAGGGGAATGTAAATGCTGAGAAATATTCAAAATAAAATGTGTAGGTCTTATTAAA +TGAGTGTATGTAGAGGCTGAAAAAAAGGGAAAAATGACTCTCAAGACAAGGTGGGCGATG +GTACCTCCGACCAAGAAAGAGAATGTAGGTTTAAAGAAAAATATATTCCAGCCGGGCACA +ACAGCTTGTGCCTGTAATCCCAACAGTTGGGAGGCCAAGGCAGAAGGATTGCTTGAGCCC +AGGAGTCGGAGACAAGCCTGGCAACACAGTAAGACCTCATCTCTATGAAAAGAAATACTA +CTAATAATTCCATCTTGGTCAAGTTTATGGGATAGCCAAGTAGATGTGCTGCGTGGGCAG +TTGGAAATAAGATTCTGATGCTGGCGGGAATAACCAAAGAAACGGCTTATAAATCATGAG +CACAGAATTGTAGCTGAAAACTTGAAAATGTATAAGCTCTCTGAAGGAGGGCACAGAGAG +GCAGGGAAACTGTCATAAAGGATGGACCAAGAATGTAGTCTTGGTTCTACATTCTTGGTA +CTGGTCAAAGAGGTATGAAAAACACTGGGAGAGTTCAACATCTGGAAAGATTTGGAAATA +GAGTTTCAAGAAAAGGAATGGACAACAGCGTCCAGTGCAACAGAATGTCTAGTAAGGAAG +GAAAGGCAAGCAGGTGGTTACTGGTGATTATCAGCGACAGCATGTCAGGAAACTCACAAA +GGAAAAGCCTAATTACCTGAGCTGAACATGACTAAAAGGTAAGAAAGTGAAGACTGAGAA +CACATCCCTCTTTGGAGAACTGTGCAGGAAAAAGGGAGGTAACATGTTAGGCAATACTAG +AGAGGGACCTGTAGCCAAAGAAGGGGTTATCAGCATGTTTCTCTCTCTCTCTTTTTGTTT +TTTTTTTTTAGACAGGGTCTCACTCTGTCATCCAGACTAGAGTGCACTGGCACAATCTTT +GCTCACTGCAATCTCGACCTCCCGGGCTCAAGTGATCCTCCTACCTCAGCTTCCCAAATA +GCTGAGACTACCAGTGCATACCACCGTGCCTGGCTAATATTTGTATTTTTTGTGGAGATT +AGAGATGGGGTTTTGCCATGTTGCCCAAGCTAGTCTCGAACTCCTGGGCTCAAGCAGTCC +ACCCTCCTCGGCCTCCCAAAGTGCTGGGATTACAGATGTGAGCCACCCTGCCCAGCCTGG +CAAGTTTCATAGACTAAAGGCAATGGTCTTAGTCTGGACCTAGACATCAGTAGTGTGTAT +ACGTACGTTTACACATACACATACACACACAGTATGGCATAGTTTAATTAGCAATTTTCT +ATCTTAGTAGTGTGGCTTACAATTGATAGTGTCTTAAATTAGATGATATATGCTAGCTGT +ATGTTTATATGAATTTCACTAGCATAAAAATAACATCACTCTAGGGGAGAAAGAATTTTT +TTTTAAGAATAGCACTATCTAAATGATGTTGATCATCTTTTTTGCCATGCTTAGCACGTA +TTCTGATCCCAGGACCATTTGACCATTAAGACAAACAAACAAACAAAAAAACCACCTTCT +TTTTTAGAGTATTTTAGGTTCTCAGCAAAATTGAGCAGAAAGTACAGAGAGTTCCCATAT +AGCCCCTGTCCCCATATATGCACAACCTCCCTTACTCATATTGACATCCCATGCCACAAT +AATGTTTGCTACAATCGATAAACCTACACTGATACATCATTATCACCCAGTCAGCATCAG +TTTCTTTTTTTAAAGCTTCCCTGATGATTCTAATGTACAAGTGAGTTAAGAAACCACTAG +ACTCAGAGGTAATGGTTTATCAAGATGGGAAGAGTGGAGATTCAAGAAAGAGGGAGCCAA +GGAGCAAGAGCATGAAGGACTACAGAGTCCAACAGATATGAAGATGCAAGCCTCAGCCCT +GCACAGTGGCTCACGCCATAATCCCAGCACTTTGGGAGGTCAAGGTGGAAGGACTGCTTA +AGGCCAGTAGTTGGAGAGACTAGCCTAACCAAAATATTAATAACGAGACCCCCTCTCTAC +AAAAACTAAAGTTAGCCAGGTGTGGTGGCACATTTGAGGTTACAGGGAGCTACGATCCTG +CCACTGAACTCCAGCCTGAGTGACAGAGAGACACTGTCCCATTAAAAAACAAACAAACAA +ACAAACATGCAAGCCTTGCACAGCTGGCGATGATACTGATACTTCTTTTTCCAGTGGCAA +TTAAGAAGCCAAAAGTTCTGAGAAATTTTAAGTTAACATTTTTCACAATTAATTTGGCCT +TTTGATTTAAAAAAAAAAAGAGAGACTACTGCAGTTCATTCAACCTAAGATGCCACTGAC +TACAGGATGTGTCTTGATTATAGAATCAATAAAATACAGTATTTTTATAATTCATTAACA +TTCATTATGTCAACCCAATAGTGTCAACATCACACCCAATTTTAAGGTCCTAAAGACTCC +TAAGTGATTAAAATTTAAATAGGAAATATGACAATTCAGCTACCTAAGAATACAATTTCT +AGAGATAAACTATTAAACCTTGTCAGTCTCTAAGGTAACGCAACAAAGTTGTACATAAAA +CCACTGACAGCTGTAGGCTCTAACACTTTTGTTATGAAATCCCACCCCAGAATCATCACA +CACGGCCTAAGTGAGTATGTGAGGAGGACGTGAGCACTCTCAACAGGCTGTCCTGAATGC +TCACAGCAAGGGGTGTATGTTCACTCAGGGAAATAAGAAGCCAGCATTAATATGGTGACA +CAATCACAGATAAGCTGCAGTCTGTATAAATGTCCACACTCAGATTTATGGAGTCTGTAA +AATTCACCTGCATATTTGATCTTTGCTTTATTTAATATCTATATTTTGTTTCATTTATTT +TGATTTTGCTCCAATTAATTTCTGAAAAACTAAGCATAAATTTGTATTCAAGCATAAGAT +TATGAATTACATACTATTTTGAGAAAGCAAGGGGGAAAATGTATTATCTCAAATTCTATA +ACTTATTCTGGTTTTATTCTTTTCTTTCACAGGGAAAAATATTTTTGCTTTTTTATTTTT +CTTTTCATTTTGAAATACTCATTGAGGTTTTTTTTTTTTTTGCAAACATTCTCTGTTCAT +CCCAAATGGATTTTAATTACGCATCATTTCTCTCTGACTGAAACAGTAAACAATGCTTTT +GCTTTTGAAGATAAAAGTTTATAATTTTTTTTTTTTTTTTTTTTGAGACAGGGTCTCACT +CTGTTACCCAGGCTGGAGGGCAGTGGTGCAATTTCGGCTCACTGCAACCTCCACCTCCTG +GGTTCAAGTAATTCTCCCACGTCAGGCTCCCAAGTAGCTGAGACTACAAGCATACGCCAC +CATGCCTAGCCAATTTTTGTATTTTTTGGTAAAGATGGGGTTTCACCACGTTGACCGGGC +TGGTCTTGAACTCCTGACATCAAGTGATCCACCCGCCTCAGCCTCCCTATGTGCTGGGAT +TACAAGCATGAGCCACCACGCCCAGCCAAAAGTTTATAATTTTGATTTTAAATTATTTAC +AACAGTTTCATTTACAATAGCATATCAGGCAGGGCACAATGGCTCATACCTTTAACCCAA +TACTTGGAGGTTGAGGTGGGAGGGTGGCTTGAGCCCAGCCTGAGCAACATAGAGAAACCC +TGTCTCTACAAAAAAATTTTTTAAACAGCCAGGCATGGTGGCATACACCTGTGGTCCCAG +TTACTCAGAAGGCTGAGGTGGAAGGATCACCTGAGCTCAGGAGGCCAAGGCTGCAGGGAG +CTGAGATCATGCCACTGTATTCTAGAGCCTGGGCAATGGAGCAAGATGATGTCTCAAAAA +AAAAAAAGAAGAGAAAGATACCATGTTAAAAGAAATTTTGTACAAAAGAAATTCAGGTTT +AGAAACCACTGTCAAACAATCAATTGACTCATCAGCTAACTATAAATGTAAAGAATCTTT +TGATACAACTTGAAACATTTCAACACTCTCCAGCTCTCTCATCCAAACTGATGGCCTGAA +TATTTTTGATGGATTATCATCCTCCTGTGTATTATAACTTCACTTCGTTCACGTTCATGT +ATATTTTGATAATTTGACAATCATTGTATAAATGCATGAATGTTAACTATAGAGTGAAAC +TGACAGAATGACAAAAAATTGACAGGATGTTCATATCTTCACAAATCTAATTACTTACAA +ACTCAAAAGGTAAAGATGGCAGCCTGGCTATAGAGCTCTTGGTTCTTTTTCTCTAATTCT +ATAATTCGAATTCTGTTTTTCACATCCAAACAGGTGGGAGTAAAGCCACCATGTGGACAG +ATCCTGGGTTCCTGAGTTTCCATTTAATGGAGCACTGCCAAGAAGAAAAACCCAAATAAA +GACACTGCAAATCAGACCAGCAAGTGTTCAAATTTTATTATGCAAAGAAACAGAAACTTT +GAGATTTTTACAGGAATTATCCTATAATCTAGAACCTGACAAATACAGGTCCCACTTGTG +ATTTCTAAATAAACACACACACACACACACACACACACACACACACACACACACACACAC +ACAGAGATACATAATAAAAAATATAAAGGTAAATACTAAAACATTATAGTGGTTCTCTCT +CAAAAATAGGACTCAAAAATCAGGGAAGTAGATAGCAATGGTTTTGTTTTTCACTTTGTA +CTCTTCTGTGCTGCTTGGTTTTGGTTTGTATTTCTGTTTTGTTTTTTTTTTTACATTTTC +TAACAAGCAGCTAATGAAAATTAGATAGCTGCTGAAAATGTCAAAGGCTATCTTAAATTG +CCAGCTGTCCGCAGTACTATAGACTGTCTTATCACATTACTAAGTAAACAAAAGAAACAA +TTATCTCATAATGTCCATTTCAACCTTTATTATCTCACTTGAAATCTGTTCATTTTGTAT +ATTTTTAAAATTTATTTTTGTATATTTTTATTCTGATTTTTACTTTTATTCATAGAAGGA +AAACAACATATCACCTCATAATGGTAAACTCTTTAATAAGTAAGATATTTTACTAAAAAT +TTCAAGTACATTCTATTTTTCTGTCTATCTTGAGTGAATAGATAATAATTTATCATTGGC +CGGGAGCAGTGGCTCATGCGTATAATCCCAGCACTTTAGGAGGCCGAGGTGGAAAGACTG +CTTGAGCTCAGGAGTTCAAGACCCCTAGCCTGAGCAACACAAGGAGACCCTGTCTCTACA +AAAAAAAAAAAAAAAAATGCTGGGCATGGTGGTACACACCCATACTTCTCAGCTACTCAG +GAGGCTGAGGTGGGAAGACTGCTTGAGCCCACGAGGTCAGGGCTGCTGTGAGCTATTATC +ACGCCACCACACTCCAGCCTGGGCAACTGAGCAAGGCCCTGTCTCAAATAAAATAAAATA +AAATAAAATAAATTTAAATGTTAAATATTAAAAAAATTAATAAACAGTATCAGACAGATA +CTAATACTGGTAATATTAGATATTAAGATGTAATACTGTATCAGACAGTATTACCATTTC +CATCAAAATTTGCAGTAAATTTTAAAGAATTCACTTCTTCATTTGTTTCATGTTTTCTAA +ATTTCTCTTGATCATTTTTACATCTGGGTTTTTTTTTTCAGGAAGAAATGCTAGATTAGT +ACCAGAATGATTTCATTCTCTGTAATGTTACATTTCAACTATTTACAAAAATATAAATTA +CAAGATTTTTAAAAAACATTAAGCCTTTGAAGTTTGCTTGAATGTCTTCTAACTTGAAGA +TAAATTTTGATTGACATAGTCATTCACTTATTTTCAAGAATTTGGTGGATAAGCAAGATT +CAAGCTTGATACTTCCTAGTTCTCATCTCCTATATATTAGATATACATGAATTTATTAAT +AGTGAAAAAATTATTGGTTGTTCCCCACTATTCATATCTGCTTGCCTCAGAACATAAACT +CTTTTTAAAATTTTTAAAAAATAATTGCTATTATTTTAAAAATCACAACCAGTCACAAAG +TATTGAACAAATGTTTAATTATAAAATAGTATATTTACACAGGCATACAATTTGTATTAA +AATTTATATTAAGTTAACAGCATGATTATATTAAAAGTTGTATGCTCATGAAATTTACAT +TTAAAATTCCCATACAAGCATTACAAATCTGCTAAGACATTGACACGAACAACAAATCCT +TCTACACGGGACGTAGAATGCTGGCCGGATAGCAACGTCAGCACTGGAATTTGTCAGCTG +AGCCATAGCTAAGTGCTCATCACTCTTCTTTGCTCTTGTATTCTACCTGCATGTTGTTGT +TTTATATTTCCCTGAGAACCACAATGTATGTTCCATAGTTTGTTTAGCTGATTTCACTGA +CTTTAGCAATTAGAAAGGAGAACCGTGGCATCCTCCCCCGACTTCTCTCAAATCCTAACT +CTCATTTCTTTTTTTTTTTTTTTTTTGAGACGGAGTCTCCATCACCCAGGCTGGAGTGCA +GTGGCGCGATCTCAGCTCACTGAAACCTCCACCTCCCAGGTTCAAGCGATTCTCCTGCCT +CAGCCTCCTGAGTAGCTGGGACTACAGGCGCACGCCACCACACCCAGCTAATTTTTGTAT +TTTTAGTAGAGACGGGGTTTCACCATGTTGGCCAGGATGGTCTCTATCTCTTGACCTCAT +GATCCACTGGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGCGTAAGCCGTTGCTCCCGG +CCACTCTCCTTTGTTTCTAAATGATCATCCTGGATAAGAGGTCAGCCAGGTCACGAGTTT +TATATTCTGAAGAAGGAAAGTGACAAGAAGCCCAAGAGGTCACACCGAATTGGCTCAGAT +TGCTCAGAGAGAGAAGACAAGAGCATCTGCTGAGATGAAGAGGAGGTGGAGGGAAAGTTT +TGCAAGTTTGGAATAGACATGGGGTGGAAAGGATGAAAAAGGGAACAGACACAGACAAAA +TCACAGAAGTCAGTATTTCAGGCTTGATGAAACCACCATTAAAAACTTCTAACTTACTTT +GCAATGTCTGGTTGCAGACAAAACCCAAATTATGTCATTACACGGCTTAAAATCCTTCAG +TGGTTTTAAGGACCGATTGCTCTTAGGACCACGTTTACTCCTAAATGTAGCAGATTTTTT +AGCCCTCTGATTTCTTCCTACCAGTCCCATCATATTCTACATGGTAACCATCTGGTTGAT +GAGCAGTTTTCCAAAGAGCTACTTAACCTTCAGGACATTTCATATGCTGTGCCCTCCACC +CAGAGCACTCTTCTTGCCCACAGCAGGAATTTTTAGTTAAATTGGATCTTAAATTGAGAT +GGACAAGACAGAGTCAAGAAATCACAACAAGATACTAGAAAATATATTTCATAAGTGTAT +AGCTTAAAATAACATTCTGCGGCATGACTTAGAAATTAAGATGCAGAGCTACCAGCTGGA +CTGTTTGGTGACCAACCTTCCCTCAATCCAACTCACCAGGAATATAAATCCTGGCATTTT +CTGTTCAGTAAGAGTCTTCAATGCACTACAATATCAACTAAAGGCTGGGAAATAAAATAC +CTGATTTCAGGGCTCCGTTAACAAAAAGGGGAATCATTTAACGTATTTAAACTATTTTCA +CCATTCAAACAAAATTACTGTTTAACCCAAATGCTTAAAACAAATTTTTAAAGAGAACAA +TCTAGGAAGAAAGTAATTTACCCAGACCTTTCTCAAGTGCATAGGGTAATTTTTCACACA +GTGTCTTCCGTAAATTGTTAAAATGTGGGTGGGGTGAGGGGTAGAGGTTTAGCTTCAGGA +GTCAGTGACTGAATGGTATTTAAAGCTTTGGTCCTGAGGAAGGTGACCTAAAGAGCCAGT +GTGGTCAGAATAGAGAGGAGAGCCAAGAAGAAAGGCTGGTGTTGAGATCAGGAGAAAAAA +ATCAGCAAAGACAACTCTTTGAAATATCCAGAATGGCTAAGCTACTTGAAAGGAAACAAA +CTGACCAGTCAGTCCAACGATTCCATCTGCCTGTTATACTTCTACTAGGAATTAATAAAC +TATTATTCTAATAAATCTGCTTTATTAATCACTGTATACATATTTCAAAGGAAAACACCT +AGCATATTATATACCCTCAAATATTAATTGGTACTCAGAGGAATATTGACTCCCTTTTAA +GTGCTAATCTGGTATCAACTGTATCCAGGTATCTTCAAAAGATCAGTATGTCTTCCAATC +CCTCCACTCTAGCTACTCCTTGGCAAGACTCCAGCTGAATTTCCCAGTTATAGGTGGAAC +CAGTTATGCCTGGTGGCTTTTGTAGCAAGAGTCCTGGGCCACTACTAACAGTTCACTTCC +TCTACCCTTCATTCCATTCCAACATTGTTGAAATTTGGCCACATTTAGTCTTCCAAGATA +CCTTAGGACCAGATACCCTACAATAATACCTATGAGCTCACACACTTTAAGATACTCAGT +GGCCGCTCACAGCCACACACCCCTTTACAGGTGCTCCACGTGGCAGCCATCTATACTGAA +TAGCGTAAAACTATTAATAGATGTGGGTGGAAAAGGTTTTGGTTTGGAGACAGATTTTCT +ATGAAGACGCAATTCAGCATCCTAGTTAAGAACGCAGCTGTCAAGTCAGAAGAACTAGGG +ATGCAAACCCAACTCTCCTACTGATTAGATGTATGAAATGGTGAAATCTCAACTCACTGA +ACCTGAAGTTCCTCATCAATGAGAATAGGATAATAAAAATCTATTTTTCTTTCTTTCTTT +TTTTTTTTTTGGAGACAGGGTCTCACTCTTATCGCCTAGGATAGAGTGCTGTGGTGTGAT +CTTGGCTCACTGCAGTCTCAATCTCCTGGGCTCATGCAATCCTCCCACCTCAGCTTCTCA +AATAGCTGGGACTACAGGTAGCACCTGTAGCACCTGTTAAAGTTGTGTTGTTAAAATTGT +GATTGCTACTGTTTGTGTGAGGATTTAGGAGCCTATGGGCAAATTTATCTGTATACCAAT +CCTCCCTCCTCCACACCAACATAATACAAAGGCTGGTGGCCCCAGAGAACAGCACTTCTT +GGGTTTACAATATACCAGGACCTGTAGTCCCAGCTAATTTTTTTAATTTTTTGGTAGAGA +CGTGGTTTTTCCATGTTGTCCAGGCTGGTCTCAAACTCTTGCACTCAAGTGATCCATCCA +CCTCAGGCTTCCAAAGGGCTAGGATTACAGGTGTGAGCCACCATGCCAGGCCGAAAATCT +ATTTCATTCGGTTGCCGTGAAAATTAACTTTTCTATGTTTGCAAATCATTCAGTATATAG +TAAATGTTTCAGAACTGGTTGTTAGAATTGTGACTACTATTGTTTGTGTGAAGATTCAGG +ATCCTATGGGCAGGTGGACCCAGAGAATAGTACTTCTTGGGTTTACAACATACCAGGGTG +AGGACAGGAGAGGTGCCAAGAGGGAAGGGGAGCTGATGGCGCCAGAAGATTTGGAAGCCC +AGGATCTAAAAGCAGACGTCCTTTTGTTGTTCTGTGCCACCCACTATTGATTCAGAGAAA +GAAACATGGGTCTCCTGCCTGACACTGTACCACATGAGGACGTTCTTCCAATGGCTGGAA +GAAAGGAAGGGGCAAAAGGTTACCTGGAGTTTAGTTACCCTCAGTAATTAATTACTAAGG +GGTCCCCATGCCACTTTTGAGTCCATACTTGCTAGTTCTCTATCAGTTCAGCCAGCCATA +ATGCTTCTGATGCTGATGTAAAAGGAAAATCTGTTCACTGATGAAAACTGAGTGTAGAGT +TCAAATCCTGGCTCCAACACCTCTTAGCTGCATAACCTTGGATAGCTTACCTGGTCACTC +CGGTCCTTTTTTCCTGCATTTGTAAAACCAGGTATGCACATATAACTCATATAGTTGCTA +TTAAGAATAAATATGACATTCAAAAGCACCAGTCTAATAATGTGTGTTCCCTTTACCTTT +ACTCAATAATTATCGGCCCCTCTTCCTGGACCACTTCAGACATTTTCTTAGGATACCACT +TAGGCAAACGGTGACAGCCTGTGATTGACCCTCTGAGAGGTTCCAGGAATAGCAGCAAGG +ACTGCTACCACCACCCATGGGCCATATTCCATGTTTAGCTGTCTGGTGGATGCCAACCCC +CCTCAAATTCAGAATCAAAACTGAATTTTCCTTCTTCCCTCCAAAACCAGATATTCTTTC +CTCTTTGTGTTCCTCCTGGTCTCTTATTAACACTACCACCACTTTCTCCAGTTGCCCAGG +CTTAAAACCAATTACAAACATTTTATTTCTTTGACCCACCCACTCACTGAGCCAGAGAAA +CATGAATCCTTCCCTCAGTTTCCTTTGGCTCCATTTCTTCTTTCCATTCCTCCCACCACT +GGACCTTAGGTCTAGACCACACCTGCTCCTCAATTCCAAATGGAGCCCTACAGAAACTAT +CTCGATTTCATCAAGTTCAAGAGTCCAGGAACTTGATGGTACCGCTGATGCTAAAAAAAA +AAAAAAACAGAAAAGAAAAGAAAAAAATTGTTGGCACATTTGAGGGAAGCTGGGCAAGGA +GGGGGAGGATATTCAAAACACCCCAAGGAAGAATAACAGGGTCACTTTTTCTTTAAAGGA +TGAAGTTTATATTGTAGCAAGTCAGAATAAGAAGAAGATACAGAGGACTAGAAGTCACGG +TTGAAATTCAGATCAGAAATGTCATCCAAATATAGAAAATAACAAATAATAAAAACCATT +TTTCCATATACAGTATTCTGTAGAGTCAGTGACATGGCAGACACGGTGATTCTAATCCAC +GGCCACAGCTTAGGAGCAGTAGTTATTTCATTTATCAATTAATTTTCTTTAGTGCCTGGC +ATATCTATTTCAAAACCATTAAGTAATTGTAGCTGTTAACTGAATGCTTACTATGTGCCG +GGTACTGTGCTGCATTATCTACATATTCTCTGCCTTGGTCCTTACCCAACCCTATGAGGG +GCACTGCAATCATTCAAAGATCAGAACTGATAGTATAGAGATGGGGGAGAGACATGTCCC +TGGGCTCACCTTTACAAGAGGAAAATGGTTTGCCCCAATAAGAAAACATTCATATAGTAC +CTAAAGTTTCCAATGTCTTAATGCTCATCATCTCATTTGAGTCACACAATAATTCTCTGA +ACTAGGCATGACATTAATTATTATCTCTGACTTACAATTAAGAAAAGCTCCAAGTCATGC +AGGCCACTGTCTTCTTGCCTTCAAACATCTCTGCATGTTTCTTTCTAGAGCTGGTGGAAA +AAGGACCATATCTGTGCCCACTTGTGAAGGGAGTAAAGGAGTATCCTTGGCATTACTAAT +GTCTCCTTTCTGATCCGAGAGAGAGTGTGTCATGAAGACACTCAGGCAGCTCCAAGTGGA +GGTCCACACAGTAGGAACTGAGGCCTCCTGCCAGCAACTAGGTGCAGGAGCCGTGTTGAA +AGTGGATCCGTTAGTCCATTCAGCCTCCAAATGACGACAGCCCCAACTGTCAACTTGACC +ACAGTCTCACGAGAGGCCCTGAGCCACACCATCCAGATGAGCTGCTCCAAGACTCCTGAC +TTGTTCCTGACATAATAAATATTTGTTGCCTTAAGCCCCTTAATGATGAGGTAATTTGTT +ACACAGCGATAGATAACTAATGCCAATCCAAACCCTGAGATATATGAAGCCTGAGGGTTT +CAACATGAAGAAGCTGACAAGAACTGGGATCCCAAGAGAGTTCATGAATTCCCTTCCAGG +AGACGTACGCAAGTGCAGATGCTGAACTGCCAGGCAGAGGTATTACAGAAGGGATGCACA +CACAGGATGGAAACTTGCATAGATATCCCTTCAGGTTACTTCCAACCACAAGACCCAGTG +AATTTAATTGTAAACGTCTCCCTAGTCTAGATGTACACACGGTTGTTGCCAGAATTGAAT +AGCTAACAAGCTGACTAAAATCTATCCAAAGCCTCCTTATTTAGAACATTTGAAATAATT +TATTATTTTTGATAGAGAAAAGTGGTCACACAGGGAGTTTCATTTTCACCTCCCACTTCC +CAAGACAACTGGCTCACTTCCCCAGCCAACCTCAACAAAGTTTTATCTCGGTGAACTACC +TGAGTCTTCTCACCCTACCTGCCCCAGCCTACCTGCCCCCCAGGAGAGTTAGAGCTCTGA +CAAAGAGGAAGCCTGAATATACCCTTACTCTTAAGGCACTGGTTTTCCAACATTTCTGAT +AATTACTACTTAACAAGCACACTGTAAACTAGTTCAACCATTGTGGAAATCAGTGTGGCG +ATTCCTCAGGGATCTAGAACTGGAAATACCATTTGACCCAGCCATCCCATTACTGGGTAT +ATACCCAAAGGACTATAAATCATGCTGCTATAAAGACACATGCACACGTATGTTTATTGC +GGCATTATTCACAATAGTAAAGACTTGGAACCAACCCAAATGTCCAACAATGATAGACTG +GATTAAGAAAATGTGGCACATATACACCATGGAATACTATGCAGCCATAAAAAATGATGA +GTTCATGTCCTTTGTAGGGACATGGATGAAATTGGAAATCATCATTCTCAGTAAACTATC +ACAAGAACAAAAAACCAAACACCGCATATTCTCACTCATAGGTGGGAAGTGAACAATGAG +ATCACATGGACACAGGAAGGGGAATATCACACTCTGGGGACTGTTGTGGGGTGGGGGGAG +GGGGGAGGGATAGCATTGGGAGATATACCTAATGCTAGATGACGAGTTAGTGGGTGCAGC +GCACCAGCATGGCACATGTATACATATGTAACTAACCTGCACAATGTGCACATGTACCCT +AAAACTTAAAGTATAATAAAAAATAAATTAATTAATTAAAAAAAAAAATTTCAGTCTTTG +AGGTTAAAAAAAAAACAAGCACACTCACACACACATTTAAACAAAAGTTGACATTTAAGA +AAACAATGGCCGGGCGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAAGCCGAGAC +GGGTGGATCATAAGGTCAGGAAATCGAGACCATCCTGGCTAACACGGTGAAACCCCATCT +CTACTAAAAATACAAAAAATTAGCCGGGCGTGGTGGTGGGCACCTGTAGTCCCAGCTACT +CAGGAGGCTGAGGCAGGAGAATGGCAGGAACCCGGGAAGCAGAGCTTGCAGTGAGCTGAG +ATCACGCCACTGCACTCCAGCCTGGGCGACAGAGCGAGACTCTGTCTCAAAAAAAAAAAA +AAAAAAAAAAAAAAAAGAAAACAGTGCTCACCATTAGAACATGAAGGACATTTTGGTCTC +ATACTGTTCTACTACTTTGTTCTTCTTAAAAAAACACTTGGTCAAAATCCACAACCCAGT +AAAAGGTCCCAAGAAACAGTATGGAGAATATATCCGAAGACATACTTCTGAACACTCAAC +AGCTCCTAAAATCCTCCTAGGTAGAGACAAAGGCAAAAAACTGAAATAATAAATCCCCCT +TCACCCCAATCATGTGTAAATACTTAGTTCCACTTCACCCACATCCATAAAATACACAAT +AAATGCTGGGGCTTTCATCTAATCAAGAACAACCTCAGGCAGTTTCTATTCAAATATAAA +TAATTATCCAGGCCCCAAAATTCTTCTCCTAGTTCCACAGGTAATGACTGGAAAATCTAC +AAACAACTTCAGCTAAAACTCCCTTATCACTCTTAACAAGTATGGCTCAAAGACAAAATT +TCAATCTTTTCCAATTTTTTTTAAAGTAGGCAGGCAGCAAAATAAAACATCAGCAAAAGC +TAAATGTGCTTGGATAAAGCACAATTAAATACATGTTTGTATTTTTCCAAAATGGACCAC +AGGTTGCTATTAAAAAGAGTAATAAAATCAATCTATAGAAACTAAATAGATAAGTGTTTG +CCTGCGGGCACGGGATGTGGAGTGGCTGTAAATAGACACAGGGTGATGAAAATATTCTAA +AATTAGATTGTGGTGATCACTGCACAACTCTGTAAGTTTACTAGAAATCACTGAATTGTA +CATTTAAAACAAGTGAATTTTAAGGTAAACTATATGGTGATTATTTATGGCAAATTATAT +ATCAATAAAGCTTTTTTCTTAAAAAATGGAAACTATATGTTAGATTTTTTTTTTAATATC +CAAGATACGTGTCAGTTAAAACAAGCAAAGTACAGAATAATGTGTATGACATGTTCCCAT +TTGAACTTTTAAAGTGATTGTATACATTACCTGCCTAGACATTTCTGGAAGGACACCCAG +AGGCTGATCATAACAGCCGCTCTGGGAGAAATGGGTCTAGGCTAAGAGAGTTTGAGTTTT +AATTGCATACTGTTTGGATTCATTTGCTTTGAACATGTATTATTTTTCATAAGTATGAAA +ATAAGATGGGTGGAAGCCCTCAGGAGTAGGACTCTTACAGCAGTACCAAGTTTATAACGG +TGCTAGTTCATATTGTTCTTTGAGAAGGGGATAGTTTGGTCCTTCAGAATTTAAATATTT +CAGCAAGGTAGGGTGGCCTGTAATTCCAGCACTTTGGGAGGCCAAGGCGGGAGGATCACT +TGAGCCCACGAGTTCAATGCTGCAGTGAGTCATGATTGTGCTACTGCACTCCAGCCTGAG +CGACAGAATGAGACCCCGTCTCTTTTCTTTTTTTTTTCTTTTTTTTGAGACAGAGTTTCA +CTCTTGTTGCCCAGGCTGGAGTGCAATGGCACGATCTTGGCTCACTGCAACCTCGCCTCC +CAGGTTCAAGCAATTCTCCTGCCTCAGCCTCCCAAGTTGCTGGGATTACAGACATGCGCC +ACCACGCCCGGCTAATTTTGTATTTTTTGTAGAGATGGGGTTTCTCCATGTTGGTCAGGC +TGGTGGTGAACTCCCGACCTCAGGTGATCCGCTCGCCTCAGCCTCCCAAAGTGCTGAGAT +AACAGGCATGAGCCACCGCGCCTGACCATGAGACCCTGTCTCTAATTATTTCTCAGTAGA +AGTCTGCGTTAAAAGGTACCTGTGTTTGACAATAAGAGGCCAAGTGACAGAATCTTCCAA +CTGAAATCTGATTTCATAAAATCCAAGAGGAAGAGAATTTGAATGCCCTCTTAGGAGGAA +AATGGGGTTCATATCATTTAGTCGTCTCCTTCGGCAGGTGCTGGAACACAACTCAAAGTG +GCTTATGGTTTGCAATTATAAATCTGGGAAGAGATTAGATACATTATATCTGAGTACAGG +ACTATATGCATCTAGGGAGTTGAAAACATAGTCCTCATAGAGCTTTATCAAAAAGAAAAA +GAATATGCAAATAAAAAACTAAAACTGAATCCAAAAAGGTAGCTGAACACCACACTCTCA +AATGTTGTAACCAGACTTTTGACAACTGCTCAGATCCAGGCCTGGGTTCTACCATCTTGC +CTCAGCTCATTTTTGGCTTTGGTTCCTAATTGAGCTCTTCACCTCGCTATTTAAGGACAC +TGGCTCTCTGAACATTGAGAACCTGTGGCTCACCGCATCCTCCCCTCCCCACCTTAGGCT +CATCCTGTCATCAGACGGCTTCCTGATTTACAAGGCCAAGGTAACCAAAATTTGGACCAT +AAAATATTAGTATTCTCAACTTTCAAACACGAGCCAACCAGATGACCTGTTTCCAGGATC +ATGGCAGCCCCTCCGACCCAGAGCCTCTCCTGCTAGTGGGGTCTTCTTCCTCCAGTGCCT +CCACTGACAAAGGAGCCACCGTCTCAGCCACCCCATGAGTCTGCCTCCCGTGAGATTTCT +ACAACTGACACTGCAGCCCCCACTTCCACTCTCATCTATTTGTGCCACTTGGATTATTTC +AACTATATTATTCAACACTCAGCCACCTGTATTTACTGAATGGCTGCTCTGCCTAAGACA +CTGGCAGGGAGGGGAGAAAATAAGGGTATTTTTACAGTAACAATTAGGACAGTGTTTTGT +TTCTAATAGCAGCTTGAGAAATAATTCGCATACTATAAAATCCACTATTTTTTTATAAAG +AGTATGGTTCACTGGTTTTTAGTATATTCACAGAGTTATGCAAACATCACCGCAATCTAA +TTTTCATACCCCAAAAAGAAACCCACATCCATCAGCAGCCTAGGCTAGTATTTTTATGAA +AAAAAAAATTTTTTCAGAGTTTCAGACTTGCAAACTTTTAAAACATTTAAAATTATAAAC +TGTCCAGGTTATCCAAAGACTGTACAGTATATGGTCCAGATTAATACAGTTAATAATTAC +CCACTCTGGGGCATATGCAACTTCAAGGGCAGAGGTAAAGATTTGCCTTGGGGAAAAATT +CAGCACAACCATGAAAATAACAAGTAGCAATAAACGGGGGGTGGGGGTGAGGGCGGGGAA +GGGGTTGCATTTGGATAGCGCCTCCCAATGCACTTGAACACTATAGCTAACAATACTGCA +TTATACACTTAAAAATTTGTTAAGAGGTTAGATCTCATGTTAAGTGTATTATCAAAATCA +AATAAAATACAACGGCGTTTTTCAATCCTCCTAACCATCTTGACAGGAATACAAGACATT +TACAAATGGGGAGCCTGATGTTCGGGGGATGGATGCCTGACTCCCAGTCACCCAGCTAGG +GGACCCCACCCGGCTCTTCTGATTATCTGGCAGAAGTGAGCAAAACAGCTCAATCCAGCA +GGCTCCATGTTAGCAGTAAGCAACTCTAATTTCATATCTGACTGAAAAAAGAAAAGAAGC +CTATTTATGCTCTCAACATAATAAAGCAGCCTTTGTTTTATGCTAAGGCCCTGGTGATTT +TTTCAGCACCAGTCCAGCTGTGACACACAGACGCTGGTTCGATGCCTGCATAAATGCTTT +CTCTTTGTTTAGTGGTGAGAACGTGAGACCTCACTAAGGCCCAAGTCCTGGGTTCTCCTG +ATGTCAACCCCACAAGTGAGTAGTGGAGCCTCACTGGCAAGGAGACCTACCTGTGCCTTT +CCCAAATGCCTGGGAAGGTAGGTTAGAGTTAGAATCTTTTAATTAAAATGAGGTAAAATT +CTAATTACTCCACAGTTGTCTCCAGAATAACATCATTTCCAACTCATCAAGTCTTATTAG +AACCGGAACCACTGGGAACACCAGCTCCACCTTGTTAACTAAAGAAAACAGCTCGCTTTT +TCCAGGAACATTAACTCTTTTTTCAGACATAAAGTAGTATTTAATGGTTTTGCTTATTAG +TCTCCAAGCCATTAATGACCTGAAAGAGATTAAACAACTTTTGAAAAGTAATCCATTGTA +AGTAACAACGGTTAAGGCTTCCTTGTAGCTACGAAAAACACCCAGAGTGCAGGACACTCA +CTTAAAATTAACACTGACTTGGATGCACACCACACACAAACAAATACAACTCCCACATGT +AATCTATTTTTATATGAATTGGTTGAAGGTGGTAACAAATTCTAAACAATATGATGTACG +TAAAAGGGTTAGCTGCACCGCACTCTAGGAAACTATTGCACCAGCTTCTACTCCTGCACC +ACTTAGCAACAGGAAAACGATGGGGAAACACTACCAAACTAACGAGTGGGTCACCTCAGA +TTTGATTTAACCCTAAACTCAACAATCTCAGGAAGTTCTGTCATACCGGCAGGAAGAACA +GACCAAGAGGAGCATTTTCAGGGGCAATACAACTCGTGTGTGTGTGTGTGTGTGTGTGTG +TGTGTGTGTAGAAAGAGTATCAATCATGACATTATGAGGCATGGATGAACCACACCACCC +AGTGTTAGCAACACGTGGATCATCTGTGGCTCTGTGCATGTGTCACTTTCCACAGTTACA +TACAAAATGTAACTCCACTACTAGACTAAGCTGTTTGAAGGTTAATTCCACATCACATTC +ATACTCCATGCAACTCACGACACATCAGCCTCACCTCCCAGACATCACTCCTAATCCCCT +AAATTCCAGCTACAGACGCCCTGTACCTTTCCTTACTCATTACCCAGTGGGTCATCTCTA +TGACCCCCAATATCACTGGCATTCACACCTCTGGGTAGGCCCCTTCCACGTGGCACCAGG +GTTGGTCTGTGTGACCAACAGAATAATACAGCTCTTGGGTTCTCTTTCTCTTGCATCATT +TGCTCTGAGGGAAGCCACGTTGTGAACAGCCTTATGGAGAGGTCCCTGGGGTGAGGAACT +GGCACCTGCTGTCAATGACCACCCAAGTAAGCTTGGAAGCAGATCCTCCAGCCCTGAGAT +GACTGATGCCCCAGCCAACAACTCTACTGCGACCTCATGGAAGACCCAGAGCCAGAACCA +CTTTCTTGGCCAGCCCCAGATTTCTGACCTGCAGAAACTGTGAGATATAAATGTGGCTGG +GCGCGGGGGCTCACGCCTGTAATGCCAGCACTTTGGGAGGCTGAGGTGGGCAGAACACAA +GGTCAGGAGATCGAGACCATCCTGGCCAACATGGTGAAATCCCGTCTCTACTAAAAATAC +AAAAATTAGCTGGGCATGGTGGTGCGGGCCTGTTGTCCCAGCTACTTGGGAAGCTGAGGC +AGGAGAATCACTTGAACCCAGGAGGCAGAGGTTGCAGTGAGCTGAGATCGCACCACTGCA +CTCCAGCCTGGGCGACAGAGCCAGACTCTGGCTCAAAAAAACAATAAAAATAAAAATAAA +AAAATATTTTATTAAGCTGCTAAGTTTTGGGATAATATGTAGCAATAGATACTAAGATAA +TAGCCACACCATCTTCATCTGGAATGTTCTTCCCTAGGTCTATCAAAATTCTGAAAAGTT +GAGATCCAAGGAAAGTGGCTTGTCTTTTATGAAAATGCTTTGGAATCTCACTCACCAGCA +TCACTTCTTTCTCTTAAATGGCATGGGTCAGTCTCTAACAGTGACGTTATTCTGTCATGT +GTTGCAATTAAGGCTCATATGCCTGCATTCCATACTAACCATGAGCTCCCAAAGGCACAA +ATCGGGTCTGTATCTTCTCATGGAGAGCAGTTAGCCTAGTCATATCAGAGATTCTCATCT +ACCCCGTACCTGTGTACAGGAAAAACTGGGAAGTGATCCTGTTGGACATTAAATTAAGGT +TGGGCTGGTCCACAGTAATAAAGGCTTAACTGTGAAGACGCTGTCTCTAGTCAAGGACCA +CAACTGGAAAATAAAGCAGGTCAGCAAAAAGGGGAAGACAAAAATTACAATCAGGCTGGG +TACAGTGGCTCATGCCTATAATCCCTTTGGATTACTTTGGGAGGCCAAGAGTTCGAGACC +AGCCTGAAGTACAAAAATGAGCCAGGTGTTGTGCCGCACAACTGTAGTCCCAGCTACTCA +GGAGGCTGAGGCACAAGAATTGCTTGAACCCAGGAGGTGGAGGTTGAAGTGAGTGGAGAT +CATGTCACTGTACTCCACCCTGGGCAACGGAGTGAGGCTCTGTCACAAAAAGAAAGCACA +ATCAGACTGGTCCTGGGCAGAACTCAACCTTCCCTTCCTTACCCCTACACTCTCCCTTAC +AGTCCCATTAAAAGAGAATAGGGAAGGAGGAATAATCTATAGAAACTCTGACTTGACGAC +ACTGCTGACTGTTGTGCCCAGAATCCAGCAAGAGCTAGGACCTCGCACACACATTCATGT +ATTTCCTCATGTGCATGTAAGGATGCACACACTCAGGGGAAGTGAGGTAAAAGTAGGTAG +TTCACCAATCAACAGAGCAACACCCTCCAAATCAGCTGCCATGTCTTAAGTATCTGGTGA +CCATGGTCACAAAGCATGAACTTGGGAATTAAATAGATGGGGTCTGGATCTTGACTCCAC +TATGAACCATATGAACTAGGAGGAAAGTACCTACTTCATGGACTCTCACATCTCCCATCT +GAAAATTACTACAAATTATTAAGGCAACTGCTGAAAAGATGAAATATGATCAATCTAGGA +GTTTGTATATACCACCAAGAACAATGCTTGTCAAATCACTCACTTCTTTTCCCCTCTCTG +GAGCCAGGCTTCGAGAAGTTGTATCCAGAATGAGAAGGTCTAAACCCTAACATAAGGACC +CAAAGTCAAGTCATCTTTATTTGCCTTTACTGCTACAAATCCCGAATGAGGGTCCAGGGT +TGAAAACATAACCCTCAACTTCACTGATAGACTTACGTATAACCCCAATTAAAAGTTTGG +CTCCTTTGGGACATACATTTCTCTTTGACCAAAACTCATTAAAACTTGGCAGGAAGCCAC +CCACAGTGAGCTAATTATACACAGCACCACCCTATATATTAATAGCTTACTGTAGCTAAC +TCATATGCTAGCATCCACCACCTGTCTACACCTTCCTTACGTGCAGGAGCCATGGATTCA +TTTCTCTCTTTTTTTAAGCTTCATAGTTTAACAAAATGTCCATCATTTTAAAAGCGACCA +ACTGATCAATCAAAAATTATCATTTCTAGAACTTAGTATCACATAACCCTAACTTAGGGA +ACTAAGAAAGTAGAAACAATGAAAAACTTACTAATGATTTGATAGTTCCATTGCAACAGG +AAGCTAAACATTTATTAAGATTTTAGTACATTCCACCATATTAAACATCAAAGCAGACAA +ATATGCAAAACACTTTACAGAAAAATGCCATTTATGTTCTTGTAATGTTCATGAAACATA +AAAATTAACATTTTAAACAATCATAAAAGTCACATTAGTTTGTTTGTTGATGAATCTGTA +AGGTGAAATCCATGTAAAATACTCTAAAATTTAAATTTTTTCCCCAAAGGATACCTCTTA +TACAACAAAAATTTTAATTTTATATGACAAATTCTGTAATCAGCTTCTAAAAATGTTGAA +GGTATAATCAGAATCAACCAGAACTTTCACCTTCTTCAAATGAAAGTAATCTCTGTCAGG +AAAAATTTGTGTAATATTTTGTAATATTACATATATCATAATATTTTGTTCTTTTTCCTA +CTATGAAGAATATCACAATATTCCAATTAGTACATAAATTACATCTTAATATTACCAACA +TACAAGGCTAGGATTTTGCAATTAGAAGCCAAATTCTGACAAAATAAAACAGTGCCTTAA +AAAACACTGAACAATTAAAAATGTTACATATATTAGAATATGGGACAGCCCATAAAAAAA +CTAATCAATACTCATCAGAACCAACTAGGCACTTCCAGCTGAGGTTAAATGACCTTTTGC +TCCTGCTCCTGTTCCTGAGGGCCTGTCTTTGTCACACAGCTGAGCCAGCACCTGCCTCTC +CATAGCAACTGCAGCATGCCCTTCAGCGCTATGAAAGATAACAGATAGGTGCCTCCTCTT +ACATTAAATATTTATTAGGTTTCTGAATAGTGGTCTTCCCAGGGAAGTTCATGGGAGGCA +CACACAACTCACAGCCACCCATCCCTCCTTCAAAAACACCTTTTCTATCAGAGTCACTGA +AATACACCCAGAAAGGGAGACCACAACCAGTTCTTTGGGGCAGACAGGTGTTGGACTGTC +TCCTTGACATGGCTTTTTGTGTGCATTTTTTACATGGTATTCGGTGTGCATTCTAACCAA +ACTCAAGGATTGTCTAAATTTGTAGGTCATCTCATTCCCTGTAGCACCTTGTCCAGTAAG +TTATAACAACCAAAAAAAAAAACCTAATAAGCATAGTATCTATTCAAAGCCTAATAAGCC +CTTATATCCTGGTTGTGTGGAAAGGATTAAGATTATAATGAGTTACTCTGTGGGTTATTT +TTTAATTCATTTCTACACACCACATGAGGTTCAAAATGAGCAACTAACTCAGGCTCAGCT +GAAGAACTCCTGGAGGGTCACTCTTTATCTGGGAAGCACTGGTGTTAAAAACTGGTGCAA +ATTTTGTTGCCACTTAGTAGAGTATTTTCACATCCCAAAGCAGAAGCACAGAAGTAGGTA +AGAGATATCAAAGTTTCCTTACAAGAGAAAGGATTTCTTTGCTTCACCCTGCCCTGCATG +AACAGCTAAGTGAAAAGCAGATTCTCCCACAAGGCTCAAAGATATAACAGTAATCTTGTT +TAATCCTAGCATGTGGCCAGAAGTGATGAATCTATGTGAAGATTTTGATGGCAGGTGATC +TTTGAGCGGGCATGGCAGTTGCACCACAAAAGGTCGAACACATTTTCACGGGAAAGTTGC +CTATGTGCTACTGAAGAAGCTAGACTATGAAGGAGCAGCCGAAATGCAAGAACACCTTCC +CCTACTTCTCTGTATCCAGGACTCAGCTCAGTGCTGGGCACATAGCAGGTGCTCCGGGAA +TGGGAATGGGTGACTGTAGGAATCATAAGAATTTTTCTTCTTTCAGGAGTACTGCACATT +CCGGGCCCACTTCATGCCCCAGAAGTTACTATTAGACAGGAACATCATCAGCAGTATGAC +AAACTAATAGGGAACTAATTAGGAATATGTAATATAGACATCAAATCTTTTCTTCAAGAA +ATGACTCAGTTTCTCTACAACCTAGGGCAACTCTAGACAATAGCAGCATTTTCACTTGTC +CGAGATGAAAGGAGGAGGGAAAAAACCCACAGTGTTCCTGAAACTAAATTTAAAAGTAAT +GCCCTTTATTCTGAGATAATGTTTTTCCTGATTTTTTGGAAGGGGAGGAGGAGTGTTAAA +AATCTCATATCTATAAAAACATGGTGGCTTTTTGTTAGTTGATTTTAATAACTTGGCAAA +ACAAGGAGTAGACAACTCAGTGTGAGCTCTCCCCCACCCAATTTTAATTTATGAATTCCA +AAAAATTAAAAAGGGTAATGCTAGGACGTAACACCCACTTGCCCTGCCTACAGCCCAACT +CACCTAACACACATCACTGTGCAGAACAGAAACAGGACAAACTGGTTTAGAAGGCAGAGG +GGACAAAGAATGCTGTATTTGGCTATACATACACGGAATCTAACATGAGGTAAGAACATC +CAGATTGGAAAAGTCTAGCACTGAAGTCGTGCAAAAAAATATACTTGGATGTATAGCCCC +TGGAAGTTCACCTAAGTGAGCCATTGTTGCTAAGGGCAATTCTTATTTACCAGGTGTGCT +GGTAGGGGAAAAAAACAGTTGACTATCACTGCTTTTAGTTAGTCTACAAAAAGACTTAGA +AAAACTGGCTAGCAGCCCAAAGCCCATTTCAGGTTCAGTTTATAAAGGGTCTAGTAAGCA +CATTTATGATTTTCCTAGCAACTCCAGGTTAGCCTCAGCTTAGGCAGAGAATAAAACAAA +CTACCTAAGGCCGGGCATTAATGTGGTGAGCATCATAGAGTGATGGTCCCATTATCTATT +AAAACAAAAATAGAACAAAAAGTGCACATGTTCATCAATTTCACTTCTCCATATTACCCT +AGACAAACATAGCTGCATAAAGGAGGAATAAACAAAGATGTTCAATGCAGGATTTATTTA +TAATAGTTAACAAAAAATACTGGAAAGAATCAAGTATCCATTAATAGAATTAAGGCACAT +TTATATGTGGGTACACTATGTAGCAGTTAAAAATAATGAAGTGATCAATATGTACTAGCA +CAGAAAGTGCTCCATGACATGGAGCTGATGAAAAATACAGAAACACAAGCATGACAGCAT +TTGATTTTCTAAAAGGCACACACAAAAAAATCCCATGCTATATAGCATTCCCAAATGTGG +TCCCTGAACCAGCAGTATCAGCATCACCTGTGAACTTGCTAAAAATGCAAATTCTCAGGC +CTCACCGCAGACCTACTGAACCAGAACTCTGTGGGTGGGGTCAGCAGTCTGTTTTAACAA +GCCCTCTGAGGGTGTGAGGTCTTGTTTTAACAAGCTTGAGAACCACTGGCCTACATGGGC +AGGCATAAAAATCACTAAGAAAAGGTTGGCCAGACTTGCACCAGATGAAGTCTCTGCACA +ACTCTCTTTATCTACACTCTTGCCTATCTTTATCTATACTCTTGTGTTCATGTATTGCTC +CTGGAAGTTAAAAGTACCATTTTTAAGATACTGCAGGTGCTAGGGAGGAGCCTGGGGAAA +TGGTTAACCATGCATCTCAGCAAAAATAAGGGAGACCTCGCTGACGGGATAGGAGAATGA +GGTTCCGGGAACTAAGAGCTACTGAAACACTGCCGATCACAAAAAGCACAAAAAACCACG +TCCAATCAGAATTTTACTCCAAAACTCTCAACAGAGTTCAGCTGGTCTTACTGGTGACTC +CGGTGGAGAGAGTACATGACAAACAGTCAACACTAGTAGGAAGGACAGCTAGCTACCAAA +GGATGAAAAAGAATGAACAATGAAGACCTTGTTTGAGAAAGCTAAACTATTTGCATAGTC +TTTTGCTGTCCTGTTTTGTTGATTCTTTAGCACTACATGTGGCAGCGGCCACCCCAGCTC +CCAGCCCCCACCATCATCCTTACATTTGCAGGGGTTGTTGAGCAGGGCAGCAGGGCAAAG +GCGACAAAAAAGGGAGCTCTGAGACCTATGGAACAAACCTTAGTGAGGCCCTCTAGCCAC +TACCATTCTAATCCCTAATCAAGCCTCTTCAAGACAGTGGGGCCTGGAAAATGTGCACAC +ACACATACATACACACACACACGCACACACACACACACACCCCCCACACCCCCTGTACTT +TATTTCCTACTAACTTCATAATCAGAAGTGAAATCAACCATTACTGCCAATGCTTGTAAA +GATAAAATAAACGCCACAAGAGTAGTCAGGAACTCACTTTAAAATAAGGTTTAGAGACAT +CTATAAATCTAAAAATAAGATAACTATACTCAATTTTCATTTGAGAGACTGCCTTAAGAG +GTAACCTTATTAATCTCCCTACTATTGCTGTAAGTCAGGTTCCAAACCAGAGCTAAAAAG +TAAGTGGTATTTTATTAAAACTTACAAATTTTCCACTTCTAAATTTTTTTTTTTTGAGAC +AAGGTCTCATTTTGTCACCCCGGCTGGAAAACAGTGGCACAATCACAGCTCACTGAAGCT +TCAACCTCCCGGGCTCAAGTGATCCTCCTGCCTCAGCCTCCCAAGTAACTGAGATTACAA +GTGCACCACCATTCCTGGCTAAGTGTGTGTGTGTGTGTGTGTGTGTGTGTACAGAGAGAA +TCTTCCTATGTGGCCCAGGCTGGTCTTAAACTCCTGGGATCAAGCAATCCTCCTGCCTCA +GCCTCCCAAAATGCTGGGATTACACGCAAGAGCCACCACACCTGGCCCTAAATTGTTTTT +AAGTGAGATTTTGGTGGATTTGATGTCAACAGTGTGTGGCATCACCCTTGACATAACAAC +ATAAAACAACAGTTTTAAAGCCAATATCTAAAACAGCCTTTTTTTAATTCTTTAACTTTC +TGACAAAAGATCAAGTAAAAGTTTTGCTCTCTGTAACAAGCACTCTTCAGATTTTGCTGA +AGAGAAAATGCTAAATAAAAGCACATTCTCACTCTGGGGTTTGGGGAACATCAGTTACTC +CAATTTCAAGCTTTATTCTCTTGGATTCTAGGAGGTCATCATAACCCACTTATATTTTGA +TACAAGCAAAAGCCCATGCTTGAAGACTGAAGAACTACAAAGAAACAGCTGTATGCCATT +CCACTTTCTGGGCCATGTTTCTCTGTTGTACAGAGAAAAATCATTTCTTTTTTTAACCTA +AAAGCAAACACAGTTCTGCTCACTTCCCACTATTCAGCCTATTTTTTTCCTCCTTTAACA +AGGCCAAATTTTTAGCTGTATCCATTAAAAAGCTTAAGTTATTTACACAGAGAAGATGAA +GCAAAAAGTGTTGTTACAGCCTCATATAAAAGAAATATCCAATTATTAAAACAAAACCAA +ACAAAAAAAAAGATTTGCCACTACATAGGTGATATAGTTTGGCTGTGTCCCCACCCGAAT +TTCATCTTGAATTGCAGCTCCCATAATTCCCGTGTGTTGTGGGAGGGACCCAGTGGGAGG +TAATTAAATCATGGGGGCGGATTTTTCCAATGCTGTTCTTGTGATAGTAAGTCTCATGAG +ATCTGATGGTTTTATAAAGGTTTTATAAAGGCCCGTTCCCCTGCACACGCTCTCCTTGCC +TGTTGCCATGTAAGACATGACTTTGCTTCTCATTCGCCTTCCACCATGATTGTGAGGCCT +CCCCAGCCATGTGGAACTATGAGTCAATTAAGCCTCTTTCTTTTATAAATTACCCACTTT +CCAGTATGTCTCCTCATTAGCAGTGTGAGAAAAGACTAATAAATTGGCACTGGTATAGTG +AGGTGCTGCTTGTAAAGATACCCAAGAATGTGGAAGTAACTTTGGAATTGGGTAACAGGC +AGAGGTTGGAAGAGTTTGGAGGGCTCAGAAGAAGACAGGAAAATGTGGGAAAGTTTGTTG +AATGCCTTTAATCTAAATGCTGATAGTGATATGGACAATAAAGTCCAGGCTGACGTGGTT +TCAGATGGAGGTGAGGAACTTGGGAACTGGAGCAAAGGTGACTCTTGCTGTGCTTTAGCA +AACAGACTGGTGGCTTTTTGCCCTAGAGATAATGGTAGAACTTTGAACTTGAGAGAGATG +ATTTGGGGTATCTGGCAGAAGAAATTTCTAAGTGGCAAAGCACTCAAGAGGAAGCAGAGT +ATAAAAGTTTGGAAAATTTGCAGTAGAAAAGAAAAACCCATTTTCTAGGAAGAAAGTCAA +GCTAGCTGCAGAAATTTGTATAAGTAATGAGGAGACAAACGTTAGACAAACATAAAGACA +ATGGGGAAAATGTCTCCTGGGAATGTCAAGAGACTTTCAAGGCAGCCCCTCCCATCACAG +GCCTGGAGGCCTAGGAGGGAGAAATGGTTTCCTGGGCCAGGTCCAGGGCCCTCCTGCTGT +GTGCAGCCTAGGGACTTGGTGTCCTGTGTCCCAGCTTCTCCAGTCATGGCTAAAAGGGGC +CAAGGTACAGCTCCAACTGTGGCTTCAGAGGGTGCAAGCCCCAAGCCTTGGCAGCTTCCA +CCTGGTGTTGAGCCTGTGGGTATGCAGAAGTCAAGAATTGTGATTTGGGAACCTCCGCCT +AGATTTCAGAGGATGTGTGGAAACGCCTGGATGTCCAGGCAGAAGTTAGCTGCAGAGGCA +GGGCTGTCATGGAGAACCTCTGCTAGGGCAGTGCAGGAGCGAAATGTGGGTATGGAGCCC +CTACCAGAGTCCCCACTGGGACACTGCCTAGTGGAGCTGTGAGAAGAGGGCCATCATCCT +CCAGATCCCAAAATGGCAGATCCACCAATAGCTTGCACTGTGTACCTGGAAAAGCCACAG +ACACTCAACGCCAGCCCGTGAAAGCAGCTGGGAGGGAAGCTGTACCTGCAAAGCCACAGG +GGTGGAGCTGCCCAAGACCATGGGAACCCACCTCTTGCATCAGCGTGACCTGGATGTGAG +ACATGGAGATCATTTTGTAGCTTTAAGATCTGACTGCCCCACTGGATTTCGGACTTGCAT +GGAGCCTGTAGCCCCTCCATATTGGCCAATTTCTCCCATTTGGAATGGCTGTATTTACCC +AATGCCTGTACCTTCATTGTATCTAGGAAGTAACTAACTTGCTTTTGATTTTACAGGCTC +ATAGGTGGAAAGGACTTGCCTTGTCTCAGATGAGACTTTAGACCGTGGACTTTTGAGTTA +ATGATGAAATGAGTTAAGACTTTGGGGGACTGTTGGGAAGCCATTATTGGCTTTGCAATG +TGAGGACATGAGATTTGGGAGGTGCCAGGGGAAGAAAGGTATGGTTTGGCTGTGTCCCCA +CCCAAATCTCATCTTGAATTGTAGCTCCCATAATTCCCATGTGTCGTGGGAGGGACCTGG +TGGGAGGTAACTGAATCACGGGGGCAGGTCTTTCTCGTGCTGTTCTTGTGATGGTGAATA +AGTTTCATGAAATCTGATGGTTTTATAAAGGGAAGTTCTCCTGCATATGCTCTCTCTTGC +CTGTCACCATGTAAGACATGACTTAGCTCCTCATTCACCTTCTGCCATGATTGTGAGGCC +TCCCCAGCCATGTGAAGTTGTAAGTCAATTAAACCTCTTGCCTTTATACATTACCCTGTC +TCAGGCATGTCTTTATTAGCAATGTGAGAACAGACTATTACAATGGGAAAGAGAAATAAC +AAAAGTATATTTTACCTCTAAAAAGAATAGGCTTAAAACTTGAAGAAACAGCCGAAGTGA +TTGTTAAAGTATATTAAACAAAAATTATGGGAGGCCACTGTTTTTGGACTAAGCTCCTGC +ACTAGGACCCAAAAGCCAGACCACACCAAAGTGAGTCACTCATGCTTACTGCCACATAAT +CATATTGAAACTTTAAAGAAGCAGTAGATCCCCAAAAAAAGATCAGTTTTTTCTGGAAAC +AGGAGATTCCAAACTACCAGAATCAGCATAATAAGAAAGTCTCTTCTGCTTTAACCTTTA +AAAGAAGTAACCTGAAGTAACTTGTTGTTAACCAATCAGCTTTTTTTTTCTATTGTTCTG +TTTCTTTGTTCCCTTATAAAAGGCACTGTTCTGACATTGCCCAGTGGAAGCTCAGTCTCT +TTTATAGAATGGAGGCTGCCCACTTACCAAATAATGAATAAATGCCAATTAGATCTATAA +CTAAATTTGTTGTAATTTTGTCTTTTGACAGGTGTAAGATATATTACAAGGTCATTTAGT +AATACATCCATTGCTAAATGAATTAGAAAGCAAATTAAGTTAAAAGCAAGACAATGTTAA +TTGCGCTTATGTTGATTTTTGTCAGAAGAGACCTAAGTACTTCCTGGTAAGCAGCTTTCA +ATATAAACAAGAGCCCTGCACCTCTCTATCACTTCAAAAATAGAATACTGCAACGCTAGA +AAGGCAACACCCAGGCTTTAGACGCACCTTCCAGAACAGACTTTTCTAAATAGCCAGTAA +CAGCTCGAGAAAGGGAGAAGATCAGACCTGCCTTTCATGCCCCCCCGACCCCAGGAGCAG +GAGGTGAATCTTGAATACCTTTTCCTACCCACAGGTAGAGAGCTGACCGGGGAGAGAGGC +CAGCCATATCCTCAGCAGGAGGATGAAGAAGCCAGGCCAACCCTTGATAGTACCTGACAG +AATCACATGGGCAGAAGCAAACTCGAATGGCAGCACCAAAGGAGGTGTGAAATGCTGTGA +TGAAAACACCCTTCCTCCTAAACACTCATTCCCAACAACAAAAAACACCCACTACCATTT +AATATCCAAAAGAGTAACTGGTGCATCTAGCTCCAAAGATCTCTCACATGAAAGATGTCA +GGCAGCCGGGAGCGGTGGCTCATGCCTGTAATCCTAGCACTTTGGGAGGCCAAGGCAGGT +AGATCACCTGAGGTCAGGAGTCCGAGACCAGCCGGGTCAACATGGTGAAACCCCATCTCT +ACTAAAAATACAAAAATTAGCAGGGCATGGTGGTGCAAGCCTATAATCCCAGCTACTCGG +GAGGCTGAGGCAAGAGAATCACTTGAATCTTGGGGGGCAGATGTTGTAGTAGCCGAGATT +GCGCCACTTCACTCCAGCCTGGGCGAAAGTGTGAGACTCCGTCTCAAAAAAAAAAAAAAA +AAATGCCAGGCACAAGCAGATCTCAGGTTTCCTTCGAATTGAGGAAACTGATAGGCCTGC +CAAAGACAGCCTATGTGGCAAGTAAATGCTTGTGATTAAGAACCTGAATATCAACTTGAC +GGGGTGTGTGCTGGGGAGGGGAGAAAGAGAGGGTACACAAAAACATTTGTGAATAAAATT +AGTTTTTACCTTCATTAGAATTGTTTCTGATAGCATATTTGACCCTGAATTTATATGTAT +ATTAAATAAAAGAAGACTCTTAGGCACTAACAAATGTGGGAGGAGAGTGCTGAGGTTACT +AGGATTTTATTACAAAGAAATGTCTTACTTCTATGCTTTCACAGGTTTCTCCACTAAGGT +TATGTATAACTTATGCAAAAAATGATAAAGAATTACTTCAAGTGCAGGAAAATACGAACT +ACATTAAGTACAGCTGCTTTGACTGCAATGCTCCAGGAACTGAAGGAAGTTAATGGCACC +ACAGGTGCTTCCAAGACACGGGGCCCGCACGGTGAGCTGTCCATTGGCTTCCCTTGGAAT +AAGCAGAGTATATTGCCTTGGAAGGAAAAACTATTTCCTCAAAGGGAGCAATGATCCCTC +AAGAAGGCTGGACAGGGGTAAGCAGAATGCTTCCCTTCCAGCACTTTCCACATCTCATCA +TTGCCCTCTCCCCTCCTAGGTCCCAGGCACTTTTAAAATCAACAAAAGCAAGACTTTTTC +TCTTTTCTTTTTTGGCTACACTGGCATCATAACATTCTACTAGAGGTTAAGTCAATAATT +CAAAGTTAAAACCTCCAACATTTGAGACTTGGTATTATTAAATAAATCACCTCCATTTTG +GCAAATTTACATCTGTAACCAATTCATTTAAGATAAGAGCTCTCTATATTATGGAGAGTC +AGTAAAATATTGGTGATAAACTCTATGATCTTGGGGAGGTCCTTAATCTCCCTAAATTTT +AAGCTCCCTCATCAGTAAAACAGGAAAAGGGAAAATACATCTGCCCAGGGCTGATGTGAG +GGACAAACAGGGCATTTGCTGCCCATAGATGCTTGGCGGGAGCCAGGCCCTAGGAAACAC +TCCTTCAATGTTAGTATCACTGTCAAATAAAATACCTTTCTTTCCACATAGAACTGGTTG +AAAAGAACTAAGAATTTCAAACTCTTCAACAGCAGAAAGGCCCAAACCATCCCCATCCCT +CCCTATGCGCCCTTTCACTCACCTTTTCCAACCTCTACAAAAAGGATGAGCAGAACCTGC +CCCACTGTGAAGGACACAATCACATCTTCTTTTGTTCACTGCACAAAATAAGGTTATGAA +GTAGGAGTGTTGGTGGGAAAATGAACACACCTTTAAAATTCTAAAAAATAATATTATCAT +CAAAAGCTAAAGGGTGACTGCATGGGCAGGCAACTTGGTCAGGAGAAGGAAGAGAGACAG +AGAAGCAACGGGCCCTGTTGTCCCCCATGGGGAGTATCAGGAGGGCTCCCAGGACTCCTG +TGGAAGAGGCAGGCCCAGCCCGCAGCCTCCCCAAGCTCTAGACACAGGTGAGGCTCTCTG +GAGTCGAACCCTCCCTGGTGGCCAATGTGCGCAAAGCCCAAGGTGGACGTGACAATACTA +CAGAGGTCTATGTCCTGGGATGGCACCGGATTTGAATTGCAATTGACTCACTGCTTACTT +CCCTCTCCCCTTAAGTGATAACAAAAAATCAAATGTCCTCTTCATCTTCTAAAAAGTTTT +TAAATTATGACACCTTTGAATCAAGAAAAGGGAAAGCTGCTGTGGCTTCTATGTTTCTCC +TCAGCCCAAAATTCATACAGAGAAACTCAAATAGCTAAACTAATGAAGTATGATTTTTAA +ATTCTCAATTAATAATTCAAAATGTTTCTTCTATGCTTTGAATCATGACATACACACACA +CACACACACACACACACACACACACACACACACACACAAAACACCTACATTAGCTTTGAA +GTAGCAATGAAATTAACTAATAAATAAACAAAGTAGGAAATCCATTTCAGGGTTTTTTTT +CTATTATTCCTGCAGAACAAAATGTTATATAATACATAAATCATACATAAATTATGTATA +TGATGATCTGTGATGAGAGACCTTTGAGGCTACTATTATAATTGTTTTTTGGGGTTGTTT +TGTTTGTTTGGTTGGTTGGTTGGCTTTTTGTGTTTTTGGTTTTTTGTTTTTTTTTTTTTT +GAGACAAGGTTTCACTCAGTCACCCAGGCTGGAGTGCAGTGGCACAGTCTTGGCTCACTG +ACACCTCCGCTTCCAGGGCTCAAGCGATCCTCCTGCCTCAGCCTCCCAAGTAGCTAGGAT +TACAGGCATAAACAACTGCTCCAGGCCTGATGTTACTATTGTAATTGCTTTCATGCACCA +TAACCATGCTTGTATAAAACAGCAAATTTAATCAATAAATGTTGTGTGTGTTCTGACTGC +TCCACTGACTGGCCGTTCCTCCATCTCTCTCCCTTTCCTTGGGTCTCCCTATTCCAGTGA +TTTGAGGTGGTGAGAGAATAAAGAGAACAGCAAGGAAAGAAATTTACGAAGAAGATTCAG +CAAGTGCAACAATGCAGAGGTATGAGAGGGCAAAAAGGCATTTATGAATCCTCAAACCAG +GTAGGGGGTGTCATGGGGTGTGAGTGCTGGATTTCTGCAAGGCTCAGGGTTGGAATAGTC +AGACGTTGAGCAGTGGAGGGGGACTCGAGGCATCTGAGGAAAAGGAAAAGTAGAGAAAAT +CTTTCAGATTGAATGGAGAAGTTACTGAGATAGAAAATACGGAAAGGGCCAGGCGCGGTG +GCTCACGCCTGTAATCTCAGCACTTTGAGAGGCCGAGGCGGGCAGATCACTTGAGGTCGG +GAGTTCAAGATCAGCCTGACCAACATGGAGAAACTCTGTCTCTACTAAAAATACAAAATT +AGCCAGGCATGGTGGCGTGTGCCTGTAATCCCAGCGACTCGAGAGGCTGAGGCAGGAGAA +TCGCTTGAACCCGGGAGGCAGAGGTTGCAGTGAGCCAAGATTGTGCCATTGCACTCTAGC +CTGGACAACAAGAGGAAAACTTCATCTCAAAAAAAAAAAAAGAAAGAAAAGAAAAGAAAA +TATAGAAAGAAGAGCAGATGAAGGGATGGAGATGATGCATTTGTTTGGGGGGTACATCAT +ATTTAAGGTCTGCTCCAGTTATCCAATACTGCATAACAAGCCACCCCAGAACTTAGTGGT +TTTAAACAACAGCATTTATTATGGTCACACTACTGTAGTTTGGGCATGGCTTGGTCAGGA +CAGCTATTCTCTGCTCCACTCAGCCTCAGTTGGGGGGACTTGAAGACTGAGGCTAGGGGC +ATCTGAAGGTGCACCCGCTCACATGAGGGGCTACTGACACCAGGAAGACCTAGCAACTGA +GGTTTCCTGGCACCTGTCTCTGTCTGCCTGGCCTCCAGCATGCAGACTCAGGGTGTCCAG +GCTTCTTACATGTTCGCTCAGGGTTCTCAAGGCAGCAGTTCCAAGAGAGGCAGGTACAAG +CTGTGTGGCTTTTTATGGCCTAGCCTTAGAAGTCACATGGTGTCACTTCCGTCTCATTCT +ATTAGTTAGAAATGTGTCACAAAGGCCAGCCCATATTCAAGGAGAGGGGAATCAGAACAC +CTTTTGGAGGGAGGAGTATCAACGAATGTGTGAACATGTTTTAAAACCATCACCAAGTCT +TTGTGGGATGTTGATGTGGGTAGATTCAGGAGTGACATATGGATTTCTAAGAGAAAGAGC +TGGGCAGGATATCAAGGTTTAGGAGACCTGAGGACGTGTGATATTTGAAGCTATTAAGCT +GTTTAGATGGCCCAGGAAAAAGAATAGGAGAAACAAGGAGAAATGAGCATGGAATGTGAA +CATCTCAGGGGGAAAGGAAGGTACGAATTAAGAAATGCAGTGCTGGACTTTCCAAGGCTG +TGGGGATGCCAAGTAGGTTGAGAGGGAAGAGTAGATACTGGATTTGGTGATAAGAAGCAG +TGGTGGATAATGCTGAGAGATTTGGGCTCTGTGGATTGGGGTAGAGTAGAAGAGAATTGG +GGTCGGGTTGAAGAGGAGTGGGGTGGGGTGGAGAAGAATGGGAGGGCTGGTACAATGGAT +TCCAGGCCTGCAGGAATGGGGGAATGGTAAAGGGAAGGCAACCAGAAAGGGAGACTGCTC +TTTGCCAAAATGGAGCTGATTATTTAATAATACCAAGTCTAACCAGTGATTTGAGGTTCC +CGCTCCACTTTGGATTGGAGGGAATTCACAAAATGCACTTTGAAAAGCTGGTTGCCTCAT +CAGACTTCACTACTTTTCAAATTTAGTATCTATAGTCATCATCATGAAATTAATAATCCA +GTCAAGAGAATGTCATCTGCAGTGACCACAGCCCCAGACAGAGCCCAACCAAGGCGAAGA +CAGGGCTCCTGGAACCAGAGGCCCCTCTTGAAGGCTAAAAAAAAAAAAGGAAATAAGTTT +GGGAAAGGATGGTAATGCTGGGAAAAATAAAACTCCTAAACCAAGAGAAATCTGCCATGC +CCTCTTTACCATCAGTCAGGATTTTCATTGAATCCCTGACACAATCAGCAGTGTAAAGTC +ACTATAAAGTCACAGCACTATAAAGTCACCAGGAGAGGCAGGCTTGGCCGATAGGTTTCC +CCCTCAACAATGACCTGAAGAAAAGCACTGACCGACTCTCAGGTCGAGGAACTGCTGTTC +TGGAATGAAAATCATTTCTCAAAAAAACCCGAGCGAGAATAGTTAACAAATCTAGAAGCT +GCACAAATCAGTCCCATAGCCAAGGCACTCCACGATGAAAACAAGCTTCAGGTTGGCCCT +TAGAAATCACTGGTTAAAATTCTAAAATCACAGCATTACTACAATTTCACCCAAATGTCA +CCTCTAGACTAAACTGCTTCTCTGGCTATCATACCACCCAGGGAAAGTATAATACTTTCA +TTCTGCAAATATTTAATATGTTCTTATTCTCTGCAAGGCTCTTACACATTAAAGTGAATT +ATTGCTTACAGACTTGAGCTTCTTGAAGGTCAAACTCTACGATATCACTATTAAAATACA +TTTTGCATTAAAAGCATCTTAACTAAAACCAGTGGCATCCACAGGCATAGCAAATCCAGT +TATTCTCCCATGCCTCTAGTTTCTGCTCTCATTTTACAAACACACACAAATGCCAAACTA +CTCATCCTCTCTACTGAGGAACTAAAAACGACATTCAAATTTAATATCTATAGTCTATTT +GCTTGGGAATATTTGCTTGGGAATAGCCAAGCAAATTCCCATCACTTAATCCAAATTTCC +CTTTAAAACACCCATGACTTCTCCAAAGAGCAGTTTCCCTTTCCGGTTGCCTTCCCTTTA +CCATTCCCCCATTCCCACAGGCCTGCAATCCATTGTACCAGCCCTCCCATTCTCCTCCTC +CCCACCCCACTCCTCTTCAACCCCAACCCAATTCTCCTCAACTCCACCCCCCACCCCCAT +CCATGGAACCCAAATCTTTCAGCATTATCTACCACTGCCAGAGTGGTGGATAATGGGGGT +GAGGGAGATGCAAACATTCAGTCAATAGCAGCTTTCAAGTCCAAGTTCAAAGGTCACCTA +CTTTGGGAATTCTTTTCTGAAGACCCCAGCCAGCGTTGCTCACTTCCTCCTCAGCCAGGG +TTATAAACTTTTCACAACATCTACTCTACTACAGCAGCCTATTTGTATGTTTGTTTCTTC +AGAATGGCCTATGAGCCTGAGAGCAGGCTCAAAGCCTAGATCGCATCACTGCACTCCAGG +CTGGGCAACAGAGCGAAACCCTGTCTCAAAAAAAAAAAGAAGTAGGCCGGGCGCGGTGGC +TCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCTGATCACGAGGTCAGGAGG +AGATCGAGACCATCCCGGCTAAAACGATGAAACCCCGTCTCTACTAAAAATACAAAAAAT +TAGCCGGGCGTAGTGGCGGGCGCCTGTAGTCCCAGCTACTTGGGAGGCTGAGGCAGGAGA +ATGGCGTGAACCCGGGAGGCGGAGCTTGCAGTGAGCCGAGATCCCGCCACTGCACTCCAG +CCTGGGCGACAGAGCGAGACTCCGTCTCAAAAAAAAAAAAAAAAAAAAAAAAAAAAGTAA +ATAACTAACTTCAATAGAACCGCATCGAAAATGTGTTTATGAAGTACTTATTGAGCACTA +TGTCCAATATCACACTTGTCTCTAAAGAAATAAAATGTTTCGTTTAAACTGGGAACCACT +GAGTTAGCATTTTACAGAAGTATCTAATATTCAGTTTCAAAAATCAGTATCTATTGAGCA +CCAGTACTAGTAACAGATTTGTACCTAATTTTCATGCATATGTGAGATATCAGCCTTAGA +GAAGTTTAGTGACTTATCCAATGTCTCACAACCAGAAAATGATGAAGCCAAATTTTGAAC +CTCGATATGACTTCAGGTTCAGTATTCTGAACTAATTTACAATCAATTCTGATGCATAAG +ATCAGACACACTGGCCAGACTCTGGTATAGATACACTGCTTGGTGCTCCTTTCCATGGCT +CCTACCACAGCTGTACTGTGCTTTTGAACAACACCTTTGCAAGGAAAAGGAAGATTGTCT +GCAACTTTTATGTAGTATAGGTATAGGCTGGGTAAGGACACGTACTCTCTAGCCAGACAT +CACAGATCAAAATCCCAGACCTGTCTGCGCCAAGCTGTGTGCCCCTGAAAAAGTTATTAC +TCTGTCCCTTCATGCCCTGTTTCATTTGTAACGTAGGGATACTGTTAGCATCTGCTCATA +GGGTATGTTCTGAAATTTTTCAAAAATAAAACATGAAAAGCATTTAGACAGAACCTGACA +TACAGAAAACAATAAATGTTGTTGCTGGTAACCACAGTAGTTGTATTACTAAAAATGACC +CAGTAAAACCCCAGCTGGAAAACTTAATTGTAATGCAAAGCTGAAGCTCTGTTACTTCCG +ATTCCAATTTTGTTTCAATTATTTGGAAAGAAAACATTTCTTTAAAAAGTATGAGATGTT +CCTAGCCCTATAAACTGATTAGAAAATGTAGTTTAGGCCAGGCAGTGGCTCATACCTGTA +ATCCCAGCACTTCGGTAGGCCGAGGGAGGAGGATCACTTGAGCCCAGGGGTTCGAGACCA +GTCTGGGCAACATAGTAAGACCTTGCCTTTACAAACAATAAAAAAATTAGCCAGGCATGG +TGGTGTGCGCCTGTGGCCCCAGCTACTCAGGAGGCTTAGGTAGGAAGATTGCTTGAGCCC +ATAAGGTCAGGGCTGCAGTGAGCCATGATTGCACCACTGCACTCCAGCCTGGGTGACAGA +GCAAGACCCCATCTCAAAAAAAAAAAGTAGTTTAAATTTTTCTTGGACTCCAGATTATTC +TCTTAGAGACAACAGATTTGGAACGAAGCTTTTGTAGAGCTCTCCACATCCAGCAGAGTA +CATCTGGGGAAGTCGTGATCATTCAGATTATGTTTCCTCATATATAAAATGAAAATGTAC +CAGTCCTACCTTCCTGCAGCACTGAAAGACTGAAACAAGATAATATGTAGAAAATTAGTA +AGAGTTCTCAAAGGCCATGTGGTATCATCGTCATCATTCTCATTCTGGGTTCTCATAAAA +TAATATTCCATACTTAATATTCCAACTTCCATATGGAATATTCCAACTTCCATACTGAAA +TGGAAGATTAATCATCCATTTGCCAAATGTCTCAGGCAGGCAAAATGTTTGCATTTTTCC +CTCTTTACAGAATTTTTGTTCTGGTTTACTAGTAGCAAGCACTTTCCACTACTGTCAACA +TACTGCTTGCCCTTCTGAAATGTGTTTTTTAAAAACTACTACTAACATGTGCTAAGGCCA +TCCATGTCTCCTAGGCTCAGAATGCATTAGAAGTAAATAACTGGCTGGACACGGGCGGTG +GCTCATGCCTGTAATTCTAGCACTTTGGGAGGCCAAGGAGGGTGGATTGCCTGAGCTCAG +GAGTTCGAGACCAGCCTGGGAAACGAGGCAAAACACCATCTCTACTAAAAATACAAAAAA +AAAAAAAAAAAAAAAAAATAGCCCGGCATGGTGGCACATGCCTGTAGTCCCAGCTACTTG +GGAGGCTGAGGCACGAGAATTGCTTGAGCCTGGGAGGCAGAAGTTGCAGTGAGCCTCAAT +CACTGCACTCCACTGCACTCCAGCCTGGGCAACAGAGCGAGACTCTGTCTCAAAAAAAAG +AAAAAGAAAAAAAGAAGTAAATAACTAACTTCAATAGAACAGCACTGAAAATGTGTTTAT +GAAGTATTTATTGAGCACTATATCCAATATCCTTTCAAGAATAAAAATTTAACCAACACC +GTCTCTTCTACCTATGTATACACACACATTCTTACATACCTGCCTTAGGAGCAAAGTACC +AATTTAACTTATATTCACAGACAGATTTTCAGTGATTATATGTAAGACTATAAGCATATT +TAGAACATATATTCCTATCTCCCTGCCAAACCATGTTCCTTCTTTAATTCTTAGTCTTTT +CTATCCAAATCCATCTGACTCTATTAATGCTAGAAGTCTTTTTGATTGATGTATGTGCAA +TATGAGAAATATTTATGGAGTACCTACTACATTCATACTTGAACTGCAAGCTGGGAATAA +AATGTAAGGCAGTCTCCTATTCTAGTGACACTATTTCTAGCCAAGTACACATTCTAGTGG +GTTGGATAAACTATCATCTTTATTTCTTAAGCCCTCCTGATTGGACCATAAGCTCCTTTT +CCACACCACAATGCCTCCAAATAAACTAAGGATACAATGGGTGAAATTTCATCCTGTTAA +TAAGTTCCCAATCCAAAACTTTTATCAAGAACACATTTATATATATATATATATATATTT +TTTTTTTTTTCTGAGACAGAGTCTCGCTCTGTCACCCAGACTGGAGTGCAGAGGCATGAT +CTTGGCTCACTGCAACCTCCACCTCCTGGGTTCAAGCGATTCTCTTGCCTCAGCCTCCTG +AGTAGCTGGGACTACAGACATGCACCACCACGCCGGGCTAATTTTATATTTTTTGTAGAG +ACAGGGTTTCGCTATGTTGGCCAGGCTGGCCTCGAACTCCTGACCCCAAGTGATCCGCCC +ACTTCAGCCTCCCAAAGTGCTGGGATTACAAGTGTGAGCCACCGCACCTGGCCTTAAATA +ATTTTTAAAACTGACATTTACATTTGTATAGCTGTAACATAAAACACACTCACCATGATT +ATGAGCCAAGGCATGTAAATTAATAGCCTGTCTGAAATCACTATTTTTAGTACCAATTAC +AAGTGTCTAAACAGAAAAGACACCAAGAAGGAAGTACTGAAAGCCACAGAAAGCCATGCA +AATTACCCCCAAAATGTCACCTGGAAAATATTTGCTCCTAATACTGTATTTTGCTAATAA +AAATAACATTGAAAGATCCAACATAACCAAAATGATAAGCAAAATAGAAAAAGTAAATAC +TTGCCAAGGAGGGAAGGTGACAGAGAACAATGAGAAGGCAAGACACACTAAGATCCCAAA +GTAGATAAGTAACAATCTCTAGAGGGAAATACAAATGGATAATAACATCTATAACCTCTC +TAGGAAACAGACAAATTGAAGCCTATAAGCTCTGTAATTTTTTTTTTAAGGAAATGACTA +GAGAGACTGAGGCAGAAGGACTCCTTGAGCCCAGGAGTTCAAGGCTACAATGAGCTAGAA +TTGCATCACTGCACTCTAGTCTGGACAAAAGAGAAAGACTCAATCTCTTAAAAAGAGAAA +AGAAAAAAAAGACAATAAAAAGGCAATTTACGTAATAAGAAAAAATATTTGCAAACCAAA +CATCCAATAAAGGGTTAATATCCAGAACATATATATAAAAAAGTCGTACAACTCAACAAC +TAATCTGATCAAAAACAGGCAAAACAGCCTGGCACAATGGCTCAACCTGTAAGTCCAGCA +CTTGGGAGTCTGAGGCAGGAGGATCACTTGAGCCCAGGAGTTCAAGGTTATGGTAATCTA +TGATTGAGCCACTGCACTCCAGCCTGGGTGACAGAGTGAGACTGTGTCTCAAAACACAAC +AAAACAAAACAAACAAACAAACAAAAAAAACGGGAAATAACGAGTGTTGATAAAGATGGA +GAGAAACTGGAATCCTTGTGTACTGTTGGTGCAAATGTAAATTGGTAAAGCTATTATGGA +AAACAGTATGAAGGTTCTGAAAAAATTAAAACAGAATTATCATATGATCCAGCAATCCCA +TCTCTGAGTATATTTCTAAAAGAAGTGAACACAGGCTCTCAAAGAGATATTTGCACACTC +ATGTTCATTACAGCATTATTCACAACAGCCAAGATGTGGAAGCAACCTTAATTTCCACTG +ATAGATAAATAATAAAGAAAATGTAGTACATACATACAATGGAATATTATTCAGCCTTAA +GAAGGAAATTGGGTCATGTGCTACACACGCATGAGCCCCGATATCATGCTAAATAAAATA +AGCATCACAAGAAGACAAATACTGCATGATTCCACCTATATGAGGTATCTAAAGTGGTCA +AACTCATAAAATCACGGTTTCTATGACTGTTACCAGGGGTAGGGGATGGAGGAATGGGGA +AGTTGGGAAGCTGCTGTTCAATGAGTACAGAGTTTTCATTTTGAAAAATGAAAAAGTTTC +AGAGATCTGTTGCACAAGGTACATACAGTTAACACTATCGTACTGTACATTTAAAAACGA +TTAAGATGGTAAATTTTGTTATGTATTTTTTTACCATGAGAAAAAGAGGGCATTGACAGT +TATGTTTTCCAGAATGAGATTCAGTAACAGGCATCGAAAAGCTTACATATATTCACCTCC +TTTGACCTGTCTATGGAAATTTATCTTAAAACAATTTCTCTTAAAGCAGTATCATAGCTA +AAATGGAATGTAAACCTACTCCAGGAGAGAAAGAGTTAAATAAACATTTGAATAGTGGAA +GAGTGCAATTATCAAAAATTATAGCTTGGGGAAACTTTTTTTAATGATGTGGTAAAATTC +TTATTATCAAATAATATCCAAAACAAAAAACAAAACTGTTATGTGTAGTGTATACAGTAT +AACCCTAATGAACATATATTGGGGTATTGAATAAAGAAACAGACCAAATTCTAACTGTGA +GAGAGAGACAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGACAGACAGACAGAAAGGGGAA +AGGGGGGAGGAGAGAGAAGGAGAAAAAGATCTGCCAGCATGATTTTTGTTGAATTTTCAC +CTAGATAAGTTGATTCTAATGTTCGTTTGGAAATAGTCTGGCAAGAATACCTAGAAAAAA +ACTGACAGAAAAAAAAATAGAGTAATCAGAGCAAACTAGCCCTTCCAGACATTTTTACAT +TTTATGAAGCTACAATAACTTAAACTAGGTTTAGCTGCTGGCAATGAACATACAGATAAA +GAGAAAAGAAAAGAATGTAAGAATTTAGTACATGACAACAGTGGTATTTCAAATCAATAG +AGGAAGAAGCCATTAGTCAATGAATGGTGTTAGGCAGTTGGGTGGCCAATTGGAGGTGGA +GGTGTTAAGATTTATACCTCACATCTCATTATCAAAACAAACTCCAGATTGAGGAAAGAT +TTAAACATAAAAAATAAAACCATAAAAGCATAAACTCAAAGTGAGGGAGGCATTTCTAAA +AATGATTCAAAAGCTAGAATCCATAAATGAAAAGAGCCATTAGTTAGGCTGGGTATGGTG +GCCCACTCCTGTAATCCCAGCAGCTTGGGACGCCCAGGTGGGCAGATCACTTGAGGCCAC +AAGTTCGAGACCAGCCTGGCCAACATGGCAAAACCCCATCTCTACTAAAAAATACAAAAA +ATTAGCCAGGCATGCTGGCACGCACCTGTAATCCCAGCTACTTGGGAGGCTGAACAAGAA +CTGCTCGAGCCTGGGAGGCAGAGGTTGCAGTGAGCAGAGATCATGCCACTGCACTCCAGC +ACTCCAGCACTCCAGCCTGGGTGGCAGAGGGAGACAATGTCTCAAAAAAAAAAAAAAAAA +AAAAAAAAAAAAGAGCTATTAGTATTTCTTCTTGGTTAAAAAAAATCACTATAAAGTCAA +AAAAGGTATGACAAACTAGAAAAAAAATTAACAACTCATCTCATAAACGGGGTACATTCT +ATAAAATACAATAGAAAAATTGGCAAAAGATATGGCCAGATATTTCACAGAAAATGCCAT +GTAGATTGTAAACATATCAAAAGAAGTAAACTACCTTTATATTAAATATATATAGTAAGA +CTTATACTGAGAAACCATTTTTCCCCTATAAGACAAGCAACAATGGAAAAGTGTGGCAAC +ATCCTGGCCACATGGCAAGGGAAAGCAAACGCTCGCACATGCTGGTGGAAGTATAACTGG +CACCACTTCTATGGAGCAGAATTTGGCACTATCAAAATTGAACAGCCACATTCTTCTAAG +AATTCTTCCTACAGACACACTGGCATTTTTATGGAATGACTTGCATACACATACATTTGC +TGCAGCTTTGTTTTAACAGCAAAATATCAGGGTGAAGGAGTTCAGGACACAGCATCCCAA +AACATTCCACTTTAGCATGCTGATTATTTTGGGCTAAAGGCACTTGAAAAACAGCAGGTG +TTAAGAAGGGCACCCAAACCTCCTCTCTTTTTCCTGAAAGCAGAAGATGAAGCTCCCATA +TGAAAGATGTCCTCCCTCTACCAGGAAGAAAGAAACATTCTTATCACAGGAAGTCCAAGC +CCAAAGAAATCTGCATAAAGAAACCTTGCTAAACTAAACCTTACCTTCCTAGTTACTTTT +CCACAACTGCCACTCTTTTTTTGACCTAGTATATAATCGATCAGGCCAAGCCACTTCCTT +GAGTCTTCATTCCTCTTGTGAGGGTAAAAGGTATGTAATACATAAAAAGCACTAAATAAA +ATTTGCATGCTTTTCTCCTGTTAATCTATCTCATGTTGGTTTAATTCCTAGGCCTCGCCA +GAAACCCTAAAAGGGTAGGGAGAAATTTTTCCTCCCCTACAAGGCAAAATGTAAATGTTC +ATCAACAGGGAACAAGTTAAATATTGTCTATAACAGTATATAAAATGTTACATCTATAAA +TAAATACATACAAATGGCCATTAAAAATGGAGCTGCTCTAGGCCAGGCGCAGTGGCTCAC +ACCTGTAATCTCAGCACTTTGGGAGGCTGAGGCGGGAGGATCACTTGAGGCCAGGAGTTC +GAGACCAGCCTGGACTACATGATGAAACCCATCTCTACAAAAATAGAAAAATTATGGCGT +GGAGGCACACGCCTGTAGTCACAGCTACTCAAGAGGCTGAGGCAGGAGAATCACTCGAAC +CCAGGAGGTGGAGGTTGCAGTGAGCCAAATTGGTGCCATTGCACTCCAGCCTGGGCAAGA +GAGAGAGACTCACTGCAACCTCCGCCTCCCAGGTTGAAGCGATTCTCCCGCCTCAGCTTC +CCTAGTAGCTGGGATTACAGGCATATGCCACCACACCCGGCTAATTTTGTATTTTTAGTA +GAGACAGGGTTTCTCCATGTTGGTCAGGCGGGTCTCCAACTCCCGACCTCAGGTGATCCG +CCCGCCTTGGCCTCCCAAAGTGCTGAGATTACAGGCATGAGCCACCACATGCGGCCATTA +AAGTGTATTTTTTAAATACATTTAGGGTTTTTTTAAAAGGGCAAGTTATAAAATGCAATA +TTCAATAAGAAATTTTGTGATTTGTTGGCCGGGCACAGTGGCTCACGCCTGTAATCCCAG +CACTTTGGGAGGCCAATGAGGGCAGATCACCTGAGGTCAGGAGTTCGAGACCAGCCTGAC +CAACATGATGAAACCCCATCTCTACTAAAAATACAAAAAAATTAGCTGGGTGTCGTGGCA +TGCGCCTGTAGTCCCAGCTACTTGGGAGGCTGAGACAGGAGAATTGCTTGAACCCAGGAG +GCAGAGGTTGCAGTGAGCCGAGATCACGCCACTGCACTCCACCCTGGGTGGCAGAGCGAG +ACACTGTTAAAAAAAATAATAATAAAATTGTGATTTGTTTAAAGCATAGATACATGAACA +GGTATAAATTAATATGCTAACTATGATTTCTCATTCTCGCACAGGATTATGGGTAATTTT +CTTTTTTCTCCATCAATATTTCTGATTTTTCTAAAATAGACAACTATTCTTAGGTTCCAA +AAGGCATTTTTACATTCTTTTTTAAAACTTCCACTAAATATTAAAATTCCTTAATCCCCT +GGAAACATTTTTCTAATAAAAATACATGGCTAAAATTATGGTTTCAGTACAGCTGGTACC +CACTAGTTTAAATAAAATTTGGGAATGTCTCAGAAGAGAGATTTCACAACAGTCAATAAT +TAAGGCAGAAATAATTAACCCCAAAAGGAAAATAATCTTAGCCTACAACAAAAGACTTAG +TAGCACAGAAGTTCCAGGGATTTGGGTGTTCTTTTTGGTTTTGCACTGTGAGTGAGCGTA +TTTGTTTTTATTACATGCATACATTATTCTGTTTTGAAATCTTGCTAAAAGATCACAACC +CCTCCTACCACTCAGCTATTCCCCTAGGGACTAGGCAGCCTGCCACATAAAAATAAATGC +AGGAAGTGAAGAAGAGCTAACAAAGACATCAGCACCATATGGAAATCACGAAACTGTTGA +CCAAATAAATTAACAGCCTGGATGGGGTGGGTCACACCCAGAGACTTGGGAGTAGACCCT +CAAAATTATTATCCATTATTCTCTACATTTGCTTTATTTTTAAATAAATGATACCCCACA +TTTCTGTTATTTATTTCTAAGGCACAATTACAATGTTAAAATGATAGTGACATATTATTG +TGTTATTCTTTTTTTGAAGCCTTTCCTCTCTAGTTTTTTGGCCTCAGGAACCATTCCTCT +TCCCCTTAAAATTATAAAGTTGTTTTGCTTTGTTTAAATTCAAACTAGTATAATGTGTAG +TGGGCTACGTGACTGTCACTTCTATATAACAGTGCTAAACTAAAGGTTATGACTAACATG +AGAGCACTCAAGTATACATATTTATTCAGCTCCATAAAAGGTAGTCAGGAGGGTTTTCTA +CACAATGTATGCTCTAGTTAGCAACACTGCTCTATCAAAGTAGGAAATACCACACACAGT +AAATGTGCTGCGCTGAGCTTAATGCTTGGAAACTCTTGAAAGGCATGATGCAATTTAACG +TATTTTAAATCATTTGATGTTCACTGAACTCTCACTGTAAGCAGAGTATTGTATTCAAGC +CCTAGGTATGAGAGAAAGTAGAAAAACAACAGAATCTGGGCCTGATACTACAGAGCATTA +GAATACTCGTGGTTGAAAACATAAGGAAAACTCAGTGTTTATTTTAAAAATTTACAGCTC +TGTTAAGTACAATCAGTAGCAAGAACAGATTTTTTGATAACTTCACATAAGAAGGTTGGA +AGAGGGATTTTCAATAGATAAATGCATGTAAGACAAGAGGTAGGGCATTTAATTTTACAA +CTAGAGTTTCATTAGGGATTTTTTAAGGGACAAATATAAGAAAACTCCATGTACATTAAA +AACTATTAAAAGTTCAACAAATCCTAAAATTTTCTGCTTTGGTTTTAAGTATGTTGCCAA +AATCACAATTCAGGAGACAATCACAGAGTTTGATAAACCTTATTTCAGCCAACACAGTTT +GCTAGTGAACACCAGGTTTAAAATCCCAGGTTGTGCCTTTTCCAGTTTAAGGCAGGAGTC +TTGCTCCAGATTCACTTAAGACTGAGTCATCCACTCTACTAGTTCTAAGATCTTCCATGT +AAAGTTATCCTCCAAGCCCAGCACTGCCTTATCAGCAACTCTCTGGCTAAGTTCTGCTTC +TTGAGAATAGACAGGGAAAACAGAACAGGAGAAAGTGGGAAACAAGAGATGGATTTGGAG +GGACACAGAGGTTACTATGGCTGGGGCCTGCTCTTGGACACTTTCCTCACTCATCTTAGG +CAGTCAACACATATTTCTAAGCACCTACTGTGTGCACTGGTAACATAAAGATGAAAAGGC +AGGTAGGCAGGTGGAAGCAAGAGTAAGGAATGGCCAGGTGGTTTTGTTTTGTGTTTGTTT +GTTTTTTGAGATAGAGTCTCGCTCTGTCGCCCAGGCTGGAGTGCAGTGGTTTGATCTAAG +CTCACTGCAACCTCTGCCTCCCAGTTTCTAGTGATTCTCCTGCCTCAGCCTCCTGAATAG +CTGGGACTACAGGCCGGTGCCACCGCGCCGAGCTAATTTTTGTATTTTTAGTAGAGACAG +GGTTCCACCTTGTTGGACAGGGGTCAAACTCCTGGCCTCAAGTGATCTGCCTGCCTCAGC +TTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACCGCACCCAGCCTTGGCCACGTTGTTC +TAACACAGCAAAGCTTTGGAGTAAATGAACTGACCCTCCCAAGGCAGTGCCTCTTCTTTC +ATTCGGAGCAGAGTCCTCCACCTCACCCAAAGAACATATGGGAAAATTATAGACACGAAA +AGACTCATCTTACAAGATAAAGATTTGAAAAAAATATGTCTTAGAATTAGACACTTAAAC +TAGTCCTATAAAAACTACACAAGAAGTTGGAATACTGCAGTGCTACCAATGACTGTTGAT +TCTTACCACCCAAGCTAGAACACAAACACTACTAAAACTAGTTACTCCACTCACGTAAGT +AAAACACAGCCGTTTAATTTACTTTGACAAGTACCAAACATAGTTATTCTAAAAACATCA +TTATGTCAAACGACAGTGTGTAACAGATTAGTATACAAATACACATGGGCACGTTTGTCG +TCATGTCTCCCCCGTCCTGCGTCGCCCCCATTGAAAGCCAGACAGACATAATGCTGACTT +ACATGGTGGCCCCTAAGCCGGCTAACAATATATACAAGACATGTGACAAGCTTTCTAACT +CAAACATTTGCATGTCTACTATGTACAAGTCATCATGTTATCCCACTCAGGACAACCAAA +GATGAAATGTTTCTAACCTCAAGAAGCTTAAAATTTAGATAATAATATGTATGTGTATAT +ATACGTTATACAGGTAATGTATAATATATATATACACATAGGTAACACATATAAAGCATA +TTGTATGTAATGTTTGTAAGCACTTGTGTTAAGTCTGAAATTAATCTGAAGGGGAGCGAG +GAAAGAGCTGAAAGACTCCAAAGAGTCTATCTTACAAGTAAATGAAAGTAAAGTACAGGC +CTGGCCCAGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCTGAGGCGGGTGGATCA +CCTGAGGTCAGGACTTGGAGACCAGCCTGGTCAACATGGAGAAACCTCTGTCTCTACTAA +AAATACAAAATTAGCCGGGCTGTGGTGGCGCACACCTGTAATCCCAGCTACTTGGGAGGC +TGAGGCAGGAGAATCACTTGAACCAGGGAGGCAGAGGTTGCAGTGAGCTGAGATCCCGCC +ACTGCACTCCAGCCTGGGCTACAGGTGGAGACTCAAAAAAACAAACAAAAAAAACACCAG +AGTCTGAAAAAAATAAAGTACAAGATAGTATATTTGGAATATGGTTTGATTTACATAAAA +ATGCACACATGACGGCACATACTGGAGGAAAATAAGCAATACATGAAAACTTGTGTCAGG +GCTCAAAACAGGAGTGATTCCTATCCTCACTTCCCAAGATTACCTACCTTGTTTTCTTTT +TTCAGCATTTATGTATCTTTTTAAAAGCGTGCCACACACATCTGCGTACAGTCACAGGCT +TATGATCAGCAGAGATCTCTAGGATGAAACTATTTAAATCTGAAAACCATGGCCTACTAT +TGCTCTATTTGGGGGTAATTTCACTTGAGCTGTTTTCAGAAGCAAGTGCACCCAACGCTA +TGGTAAATTAGACTGAAGGTTTTGTGTTGTGGGATTTCACCCTTCCTACGAAAAGCTCTC +TTCCCTCAAACCCACAGACACCACTCCACAATCTGGGGGTTTCTAGTATGATAAATATCT +GCCTCCCAAACCCCCCATGGGTCATACGCCACCAAAAATCCTAACCACCTGAACTTAGAA +GAAGGCAGAAAGTCTTAATTTATGAGGGAGAGAGGGGTTTCCCACCTGGAGGGACGAGAG +CGACTCACTGTCCTCTGTTCCTGGTTCCAGTCACTTACAGGAGCTGGCTGCGCCGTGCTC +CCTTCACGCGGCTTTCCACCCAAAGCGCATCACGGCCGCCAGCCCCTGACGCTAGCCCCT +TCGCCACCTCCCAGAACCTTCTCTCCCTCTCCCCCACACACGCACACTCACACTCACACA +TGCAGTCCCATCTGCCCCCGCCAGAGCCGCTCCTTCCAGGGCCCCAGGATGCCAGATCCG +GATCCGGGAGATGCAACTTGCGGCGCCGGCCCAGGAGGCTCGGCACCTGCTCGAGCCGCC +GGGCCGCGCTCAGCCCCGCGCCGAGCCAAAGCCCGAGTCCAAGCCCGAGTCCAAGCCCGA +GCCCAAGCCCGCTGGGTCCGCGCCCTCACCTTGCTCGCCGCGGTCCATGTCTCCAGCCCG +CCGCCTCGTGTCCTCTGCAGCACCCCCGCCTGCAGCCCGTCCCGGCTCGGATCGCCCGCC +GCGCCGCGCAGAGCTCCTCCTCGCCTCCGCCGGCGACTCCCGCGAAGTCCCCACCCCCAG +AGGCGTCGGGCGCGGCGGCGCCGCCCGCCCTCGGCCTGGAGCGCTTTCCTGGGGCGTCAC +CCAACCACCTGACCCGGTCGACCTGTGCGCTCCGCCACGTCGGCGCGGGCGGCGCAGCGC +TAGGAGGGCCGGGCGCACCCCGACTCCCGCACCGGCTGGAAGTCGGCCGGGAGGAGGGAA +GAGGACGGCGAGGAGATGGACTCGGCCATGGAGGCTGCGTGGAGCCTGCTTGGGAACCGG +GATGGCGTTTGCCTTCCACCATCAAGTTATTTATAAAATCAAAAGTTTCCTCCGAGGCCT +TGGAGATGCCCTTTCTCTGCATCTGCGAACACCTACTTTCCTATACTTACAGTAGGAAAC +ACAGGAACGTTATTTAGAAATGCCAGTGGCTCTTTTCTCTCTGTATTTTATTACCTAAAT +AATGCCCTATGATGTCTTCTCTAACTAGGTCATAAACCAGCATAGGTGAAAATTGCAAAG +AATCTCTTGAAAAATTATATAGTCTTTTCCATAGAATGCGGATTTTTTAGGTGACTAGGA +AGATTTTCATATAATAAAAATCTGTTTTGAGTGCGGGACTGAGGACAACACTAAAATGAA +TTAAATCAAATGAAATTAATTAAATTAACCGAAGGTCAGAATTATCAGCAGAGATCTTTG +GAAAATGCGTGTTGAGGCGTCATGTCCGTTGATCAAAGGACAGTTTGAGGTTCCCGTAAC +AATCCAGTTCTTTTCATTAGTAGCGTTAACAATCTGTTTTCACAGGGTTTTGCAGTTACT +CGTCTTCCATGAAGTCACTTTGATTGTATGGGTCATGGTCTTCAGGTGGTGTCTCAATTT +CGTAAGCTATCTGAGGCTGCAAATGAAGTGGGGCTTCTTTTCTGTGTTGCTTGACGTTTA +GGCCGAAGCATTGTGTAGCACTCCACAGACAACAAAGAAGCACTTATTCAGATGTTTTAA +AATTACTTGTAGTTACCTGAAGTGACTGTATGCTATTAATATCTCTATACTGTCGTGCTG +TATGTAAAGTGTAGCTCTCTCCAGCCTGCATCTTCCAGTGTCTTCTGGGGACGTTTACTG +TTTGACTCAACCAGATGTGATCTCTTCTATTTGAGTCCTTCTACTCTGACTGCACTTGGC +TCCTCTCCTGTGGCACTCACCCCAGCACTGGTGCCAGGATGCTACCAGTGTATGTTTCAC +AGTCCTATTAGGTTACAAGCTCCAGGTGGTAAAGTCCTTAAAATGGCCTATTAAAAAAAT +CAAAAAACAGGCCTGGCACGGTGGCTCACGCCTGTAATCCCAGCACTCCGGGAGGCCAAG +GCGGGTGGATCACTTGAGGTCAGGAGTTTGAGACCAGCCTGGCCAACATGGTGAAACCTT +GTGTCTACTAAAAATACAAAAATTGTCGGGCGCGGTGGCTCACGCCTGTAATCCCAGCAC +TTTGGGAGGCCGAGGCGGGCGGATCACGAGGTCAGGAGATCGAGACCATCCTGGCTAACA +CGGTGAAACCCCATCTCTACTAAAAATACCAAAAATTAGCCAGGTGTGGTGGCGGGCGCC +TGTAGTCCCAGCTACTCGGCAGGCTGAGGCAGGAGAATGGCATGAACCCGGGAGGCAGAG +GTTGCAGTGAACTGAGATCACGCCACTGCACTCCAGCATGGGCAACAGAGTGAGACTCCA +TCTCAAAAAAAAAAAAAAAAGTTCCAGGTGGGCAAAGATTATTTTGGTCATCTCTGCATC +CTTTAATTCTACCATGCAATTAATAAATATTGTAATTTTAAACCAGGCATGGTGGTGTTT +GCCTGTAAACCCAGCTACTCAGGAGGCTAAGGCAAGAGGATTGCTTGAGCCCAAAAAGGT +GCAATATTTTTTAAAAAATTTTTAATGTAACATAAAGGTAAATTTTGGCATCAGCAGAAA +ATTCTGTATGTGGTAAAGAATTTTTGACTAGCTGATGCTGAGATCTATTGTATAGAAATA +AACATCTGGAGAGACAATCTCTCAATGTACTAATTTGTGGACAAATAAATAGCACTTGAA +CGTGAGTGTCCGTTACAAATATTTATTGTTTGTATCTGTTTAACTTACTATATAGTGATG +AACTTGTTATGTATGCTGAAAGGAAAAAAAGTCTTATCTTTTGAAGAGCTTATAGAGTAG +TTCACATGCAGCAGAGATGGCAAATAGCCTACCTGATAAACAGCCTTCCTGTTTTCCTTC +CTAAGATAACCTAAATATTGTTTGGAGTGGCAATGTGCCCAGCTGAAACACTGGGCACTT +CAAACTGCCTTGCAGCTGGAGGTGGGTCTCTCTCATTAATGTCCAATGAGATGTGAGCAA +ACTGTACTAATTGGAATCTCCAAGAAAGCATTTAAAAAGAAGACAGACTTGGCAGCATTA +CTTGGCCCTTCACCCTTCCCATTCCTGCTTAGAGGGGCAATAGCCATTTTGCAAACACGA +GGAAGAAATTCACAAGCCAAGGACGGCAGAAAGAACCCAAGAATCCATGGCATCAGAGAC +CTGCTTCTTACTGGAAAAAAATAAATGCCTGACTTTGTAAGGCCACTGTAGTTGGCTTTC +TGTTAGATGGAGCCAAATGCAATCCCAACTGATAGAATGCGCCATATAGAAAATGCACTC +TGGCATGCACCCACGTAGGTGGATACATGCAATCCTGAGCCTTAGAGATAGATTAACTTA +ATTTTCTCTTTGAGGTTAAATGAGCACTGTTCATACTATAAATATCCTAGTACATGATAT +TTCCACAAAAGCCTGCTTTTCTCTTACATCTTCCTACTACATGTATTTCTACAAAAGCCT +GCTTTTCTCTTGTGTCTTCGTACTACTTCATTTGTTTTCTTCTGACAGAATCTGTGCTTA +CAATTTATGCTGTGTTACTTCTGAAATGAACAGGTCTTATGTTTTAGCACTCTGAGGAAT +CTCTGGAGAATGGCTAGCACTTAAACAGAGCACCTGGGTGCATTGAGTTGAACCACATTT +AAAAGGCTCAGTACAGGAAAGAAACACTAGATTTACTTTGTGGTGTTATTGTTGATGGGA +ACGTGGATTTTTTTTAAGTTTCTTTTTTTAAGTTTCTTTTTTCAGAATACTCATTTGTTG +GTGAAATTTTTACAAGAAATTGTAAACTTCCCCTGAAACAAATGCATTGAAGCAAATGAA +GGTATTGAAAAGGATAGATAGAAACCGACTTATGTAAGTGGAAAAACTCTATACTCTGCC +CTTGTTGTATGTATCTTCCTTGACCGATAGCCAGCAGAAATCACACAGAATGTGTGGCAA +GTGGGATGCTTTCTGTAGTCTTACCCCTCATATTTGTGGGGCCTGGGGCGAGGATACAAA +TGGAGCCCCTGGCTTTCTCTTCTGGCTCTGTCCTTTCACTTTGACTCTGTCCTGCACCAG +GCTGGCCCACTCCCTTGTGCGTGGATGCCTTAGGACATATCCCATCTCTATCCACCCTTT +CCCATCAGCCGAGCCTTGGCCATACCTCCATTCTAGGGTTGCACTCAAAAGGACTGTCCT +GGGAGAAAAGCTGAAGGCCTTGACAACAGATGTTGGCCAGTTTAGGCAAGAGATTCTGTA +GTTATAGGTATCAGATGCACCGTTGATAAAGAGGGGGTAGATATTTGATGCTAGGGACTG +CTCATCAAGGAGAACAAAAGTGGGAAGTCTCTATGGGACCCAGGGCGCCCAGTGGAGGGG +CTTCAGGTAGCCTGGGTCTAGGGTTGCTGCCAGATAAGATAAAAGGACACCCAGTTCAAT +TTGAATTTCAGATAAATGACAAGTAATTTTTTAGTGTAAGTATATCCCTGGCCAGGAGTG +GTGGCTCACCCCTGTAATCCCAGCACTTTAGGAGGCCAAGGTGGGTGGATCACTTGAGGT +CAGGAGTTCGAGACCAGCCTGGCCAGCGTGATCAACCCCTGTCTCTACTAAAAATACAAA +AAATTAGTTGGGTGTGGTGGCACATGCTTATAATCCCAGCTCCTCAGGAGGCTGAGGCAG +GTGAATCACTTGAACTCGGGAGGTGGAGGTTGCAGTGAGCCAAGATTGCACCACCGTACT +CCAGCCTGAGTGACAGAGCAAGACTTCATCTCAGAAAAAACCCAAAAAAGTATACCCTAC +AATATTTGCAACATACTTATACTAAAATTTATTATTTATCTTAAATTCTTAGCAAGTTGT +CTTATATTTCTATTTGCTAAATCTGACTACCCTACCTATGTCAAAGGGTAGTTCTGGCTC +TCTGATTGTTCAAACAAATGAAGGCATATGATACCACAATTTTGAAAATTATATCATCAT +CCAGGAGAAAGATAGACTCTTCCTGCTTGAATCATGGTAGTAAACAAAGGGATGAAGGTT +AGGAGGCCCAAGAGATCAAGAACAAGTTTTGGAGAAAAATTGATTTAATGTCAGGTAATG +AACATTTTTTTGCTTAAGATAATTGAATAGCCATCTTATTGTATTCTCTTAGCCATCCAT +GTAAGAGACTGACTGTGAATATGAAATAAACAACTTTTAAAAATGTGTAGAAACAGGTAT +TGGCAGGAAAGAGTACTTAACACTAATGGAGGTTGGACACATAAATACCTAAACATTAAC +AGGAAACGATCTCACACTATTGATTTTGGCTACATTAAGAAAAGCCATAGACACTTAATC +TTTCTTGTATGTTTTTAAGCCACTCTGGATTCTGTGTATTTATCAAATTACATATGGGAA +CTGGGTAGGGAAGGGAGTGCTGGGAGAGCCATTGTCCCTTTTCTCCTGGAGTCTCCACCA +TCACCGTTCTAATCTTTTCATCTCTCTCTAAGATTACTCCAGGGTATAAAATGCATTAGA +GATATGTATATTTAACAATTAAATGATTAACAATATTTCTAAATTTTTACACGGTGTTCA +ACTCAGTGTCTTACAAACCATTTCACCCCTGCAAAGATAGCTAGTTTTCCAGAATGCCAA +TGGTCCTCTGGCAGAAATGGTGTAGGCCAGAATGGCAAGTGCCCAGGGTCTTTGATGAAG +AGCCAAATTCTGTGCCACTGTCACCAAAATATAACTCTGCAAGACCAGAAACAACTGAAA +ACTCTGGAGTGGATTTATCTAAACCATCACTTTAAACTATCTGGCCAGGCACAGTGTCTC +ATATCTATAATGCCAGCACTTTGGGAGGCCAAGGAGGGAGGATCATTGGGGGTCAGGAGT +TCAAGACTAGGCTGGCCAACATGGCGACTAAGATACAAAAATTAGCCAGGAGTGGTGGTG +GCACATGCCTGTAATCCTAGCTACTTGGGAGGCTGAGGCACAAGAACAGCTTGAACTCGG +GAGGCAGAGGTTGCAGTGAGCAGAAATGGCACCACTGCACTCCAGCCTGGGTGATGGAGT +GAGACTCTGTCTCAAAAACAAAAACAAACAAAAACATCACTATGGATCTGAGTGTGGTGG +CTCAGACCTGTTATCCCAGCACTTTGGAAGGTTGAGGTGGGAGGATTGCTTGAGTCCAGG +AGTTTGAGACCAGCCTGAGCAACTTAGTAAGACCTCCTTGTCTCTACCAAAAAGTCAAAA +GTTAGCCAAGCATGGTGGTATGTGCCTGTAGTCCCAGCTACTCAGGAGGCTGAGGCAGAA +GAATTGCTTGAGCCCGAGAGGTTGAAGTTACAGTGAGTCAAGATTGCACCACTGCACTCA +GTGTGGGCAACAGAGCAACACTCTGCCTCAAAAAAAAAAAAAAGAAAAGAAAAAAGAAAA +GAAAAGAAGAAGAAAGAAAAGAAAACATCACTATCTTAGGCCTCTCACTTAAGCTTCTCT +GGTTCACTGTCCTCATCTCTAAACTATGGAGTCATACTTTAGGATAAAGATGGCATATCA +GACACATTTTTATTGATTGATTGATTGAGACATGGTCTCAGCTGTTGCCCAGGCTGAAAT +ACAGTGGCAGGATCAATGCAGCTCACTGCACTGATGTGCAGCTCACTGCAGCCCCAACCT +CCTGGGCTCATGCAGTCCTCCCATTTCAGCCTACTGAGTAGCTGAGACTACAGCCATGAA +CCACAGCATCCAGCCTTATTTATTTTTAAAATGTTTTTTATTGAGATATAACTCATGTAC +CATAAAGCTCACCCTTCTGAAGTAAAAAATTAAGAGGTTCTTGTAAATTCTCAACATAGA +TTCATTCTTACTTCCTCTCTATGCTGCTAAAATTACAGTAAAGAGATAAACTCACAAGGA +CAAAGAGAATGTGAGTGTCTACGTAATGATAATTGATCTTGTGAATCTGAGAAGGCCAAA +TGCTAAACTGGGAAAGCCAAGAAGAACCTAATTTCCACTGCAGCACTTCCAAAAACCTCA +GGACTTGGCATCAGGTATCTGTGGATGTAGAAAGAAAGTGAGGCTCAAAACAAGAGGATT +GGTTGAAAGTTTACTTAAGAAGTTGGGTCCCATCCCCTTCCCTATTCTGCAAGAATACTA +AAGTGGCTTCTCTGGAGAAGGAAATTTGACAATCTCTTTACTAGAAGACTAAGTACATTT +GAGGCTGAGGATTTCCTAATACAGGCAGAAAAATTCATTAGCAGTTCACATCATGAATGC +TGTTTCTCCAGCCTTGCTCTGCTTGGTTCTCAGGATGCAAACAGCCAGGCATATACTGTG +AAAGCAGGAGACTGAAAGATCCATCTCTCAGGAATTTAACCAACCTAAGAGTAAAGAACC +AAAAATGTTGACATTGGATAAACCAGATCACCTTACCCTCAAATCTATGGTCACAAATCT +TGCCCACGTACCTAAAGAGACCAGTCAGCTGCTTCATGCTCAGGGCAGGCAGCCATGATC +CAGAGAAAAACCCTGATATGGTTTGACTCTGACCCCACCCAAATCTCATCTTGAATTGTA +ATAATCCCTATGTGTCAAAGGCGGAGCCAGGTGGAGATAATTGAATCATGGGAGCAGTTT +TCCCCATATTTTTCTCGTGGAAGTGAATAAGTCTCACAAAATGTGATGGTTTTATAAATG +GGAGTTACCCTGCACATGTTCTCTCTCTTGCCTGCTGCCATGCAAGACATGACTTTGCTC +CTCTTTTGCCTTCCACCATGATCGTGAGGCCTCCCTAGCCATGTGAAACTGCGTGTCAAT +TAAACCTCTTTTCTTTATAAATTACCCACTCTCCAGTATGGTTTTATTAGCAGCGTGGGA +CCCAACTAATACAAGTCCCTTAATGGAAGATAAAGACCAAAATAAACACCATAAAAAGGC +AACTTACAGGAAACAAACTATACAAGGAGAAGGAAACAAACAGATCTTTAAAGCTATTGT +TATTATATTCAGAGAGATAAGTGAAAATATCCTAAACATGAGACAAAAATAGTTTGCTCT +ATAAAAAAATGGAGCATTCAGAGAAAAACCAGTTGTTAGAAATTATATTATAGCAGACAT +TAAAACTCCTGTGGTAGGTATCATTTGGGATAAAGATCTCCAAGGATGTCTGTGTCCTAA +TCCCAGAACCTTTGGCAAAAAGGGACTTTACAGACTTGATAAAGGTTAGAGATCTTGAGA +GAGGAAGATTATCCTGGATTATCAGATGGACCCACTCTAATAACATGTGCTCTTTTGTTT +TTGTTTTTTGAGACAGGGTCCCACTCTGTCACCAAGGCTGGAATGTAGTGGCATGATCTT +GGCTAACTGCAGCCTCGACTTCCAGGATTCAAAAAAATCCTCCCACCTCAGCCTCCCAGG +TAGCTGGGACTACAGATGAGCACCACCACACCCAGCTAATTTTCATATGTTTTTGTAGAG +ACGGGGTTTTGTCACGTTGCCCAGACTGATCTTAAACTCCTGAGCTTAAGTGATCTGCTC +ACCTTGGCCTCCCAAAGTGCTGGGATTACAGGTGTGTGCCCCTGCACCCCACCTACATGT +GCTCTTAAGAGCTGAGAATCTTGTGACTGAGAGATGCCACAACAGAAAAAGAGGCAGGAG +AGTTTCGAAAGCATGAGAGGACTTGACCCACTCTTGCTGGCTTTGAAGATGGAGAAAAGG +GGACCATGGGCCAAGGAGTACGGGTGACCTCTATAAGCTGAATGAGCCCTTAGTTGACCA +CCATCAAGAAAACAGGACCTTAGCATACAATCATGCGACACCGAATTGCAACAACCTGAA +TATGCAAGAAACAAATTTTTCTCAAGAGCCTCTAGAAAGAACATACCTTGTTAGTCCTAG +ATACCTTGACATTAGTCCTGTGAGGCTCATGTTAGACTCCTGATCCTCAGAACCATAAGT +TAATACCTCTGTGCTACTTTAAGCCACTCCATGGTTGGTTTGGAGTATAAAGTAAATTTT +CTAGAGAGAAGACCAAAAAACAAAGGTATGAAAAATAAAGGGGAACATATAAGAAAATCA +GAAGACTGATCCCAGAGGTCTAACATCCAAAAAAGAGGCCAAGAGAAAGACATGGAAGAA +ACAGAAAAAAAGAAGGAATCAGTGAAATAATTCAGGGAATTTCCCCAGACTGAAGGATTT +CCAGATTGAAAGGGCTCACTGAGAACACGGCACAAATTTATAAAGTTCAGAACACTGGAG +ATAAAGACCCCACAAGTTCTAGAGATGGAAAAAAAATGGTCACATTCAAAGTAAAAGGAA +TAACAATGGGTTTGGAGTCATGGACAACAAAACTAGAAGACAATGGAGGATTAGGCTTAA +TTTACTGAAGAAAAGTGATTTCTACCTTATTTTCTTCTTAGATTGAAAAGACAGAATGGG +AGCAGGTAAGAAAGTTAGGAATGAGTAATACTGAGGGGTGAATAGAAAGGATGAATCCTC +ATCATTCATAGTGGAAAACTGGTGGATAATGCCGAAAACTGGAATTATCAATATATGCAA +GTTATTTAAAAAAAAAAAAAAAAAAAACTAGGCCAGGTGTGGTGGCTCATGCCTGTAATC +CCAGCACTTTGGGAGGCCAAGGAGGACAGATCACTTGAGGTCAGGAATTCAAGACCAGCC +TGAACAACATAATGAAATCCAATCTCTATTAAAAATACAAAAATTAGCCAGGTGTGGTGG +TGGGAGCCTGTAATCCCATCTACTCTGGAGGCTGAGGCAGGAGAATGGCTTGAACCAGGG +AGGCAGAGGTTGCAGTGAGCCGAGATCGCGCCACTGCACTCCAGCCTGGGCGACAGAGCC +TAGACTCTTTCAAAAACAAACAAACAGAAAACCTAAATGATTTTGATTTGAAAGTGGTTG +CCTTCAAGGAGGAAAATGCAAAGGGTAAGAGGGTGGACTGCTGGGTTTTTCTGTTTTGTT +TTTTGCTTTTTTGCAAAAATCCTTGTTTGCCTCTTTAAAATATGTACATGTTTAACTATA +AAAAACTAAAAACTGGAAAGTAAAAATAAAAAGACTGATAAATTAGTGAGACAATAAGCT +AAAAAAACAAATTAGGTTGCATGAATATACTAGGTAGCACAAACTTTTTTTTAGGGAGAA +GTTATTTGCTATTTCCCTGAATCCTTGAAGTAGCCATGAAATCTCTGTGTTTGTTCTTTG +AAGAGAGCTCTCAAGCCCCACACATTTCCAGTGAAATATAAGGACCCTTACTGACACTAT +TTCCAATTTTCCTTTCAGCTCTGAAAATCTATGGTGCGTAGGAAGATGGACAAAACATTC +TTCGTGATGAGAAAGCAAAGCAGATTGTGATCACATTTTTGGAAAAAATAGATTTGCATA +TTCGATCTTATGCACAGAAAGATATCTGGCAAGACATTGACAAATGTTAATAATAGTTAC +TTCTTGATGATAGGCCCAGATTATTTTTATTATCCTCTTTAGTTTGTTCTTGATATTTTT +TTAACACTGAGCTTATCATATTAACAGTAATCTACATTGTTTAATAGGTACGGGCTGAGC +ATGGTGGCTCATGCCCATAATCCCAACACTTTGGGAGGCCGAGGCGAGTAGATTGCTTGA +ACCCAGGAGTCCGAGACCAATCTGGGCAACATGGTGAAACCCTATGTCTACAAAAAATAC +AAAAAGTAGTTGGGTGTGGTGGCGCATGCCTGCAGTCCCAGGTACTTGTGGGGTTGAGGC +GAGAGGATTGCTTGAGCCCCGGGAGGTCAAGGCTGCCGTGAACCATGATTGCCCCACTGC +ACTCCAGCCTGGGCAACAGAGTATAAGAACCTGTCTCAAAAAAAAAAAAAAAAAAAAAAA +AAAAAAAAAAAAAACACACACACAAAAAAGAAAGAAAGAAAAGAAACAGGTACAGAGTTT +CAGTTGGGATGATGAAAAAGTTCTGGAGTTCTGTGAATGTACTGAATGCCACTGGGCTAT +ACACTTTAAATGATTACAGTGGTAAATTTTATCTTGTGTATATGTTACAAACACAACGAA +AAAGAGTTATCCAATACTTGCCCTTTATTCGCTTCCAATTAATTATTATAAATAACAGTT +AACTGTTTGAGAGGGTCAGAAAAAATGTCAAACAAGTTTAAAGAAGATGTGACCAGCCTG +GGTAACATAGACCCCATCTCTATATTTTAAAAATAATTTGTATAATTTTTTTTAAGTTTG +AAGAAGACACTGAATACTGTGAAATTGCCTAACAATTGATATTTTCTGAAGGCAGCTCTC +TTGGTGGGATGTAACTCCTAACTTTCTCTCAAAAGTTTTTGTTGTTGTTGTTGCTGTTGT +TGTTCCATAAGGAAAATGAATTTAAGAGAAGTTTGGGCCAGGCACAGTGGTGCACACCTG +TGATGCCAGCTGCTTGGGAGGCTGAGGAGGGTGGATCACTTGAGCCCAGGAGATTGAGGC +TGCAGTGAACCCTGATTGTACCACTGCACTCCAGCCTGGGTGACAGATGGAGACCTTGTC +TTAAAAAATTAAAATAAAAATAAAAACGAGGGGCAGTTTGATTCTCAGTAGGGGCATGAG +AAAGATAGAGTAATATGGTTCCCCCAGGCAAAAAAAAAATTTTTTTTAATTTTGAGATAG +AGTCAAAATTTAAAAAAAGATCACGCCAGGCTGGAGTGCAGTCACCTCAAGTGATCTGTC +TGCCTCAGCCTCCCAAAGTGCTAGGTTTACAGGCATGAGCCACCACGCCTGGCCAAAATG +TTTTGTCCATTGTTGTAGTCAGGGTCCCTGTCACATAGCTTGTGAGATGGAGATTTGAGT +GCCGGGGGTGGATTGGTGAGCACCCTGGGATCCGACCTGTTGGGAAGAGAAGCCAGAAGG +ATTCAATGGAGGAAGAATGGACTGTGTGTGATGCAGTCACAACAGAGGCCTCATCCCATT +CCTCCAGAAGCTCTGGAGCCACAGTGTCTCTTCAGAGTTGTCCCAAATTGAAGCAAATGG +CCCTGCCTTTATAGCCCCATGCTGATCCACCCTAGGAAGTGGGCTGCCCTCAGGAAATGA +TCTTGGGCAAGGTGGCTTTTCAAGATTGATGGCAGTTCTCACCAAGGAACTTCCCAGAGG +ATCATCAGCTGCCAACGTTCCCAGTCCTGAAGAGAAGATGTGGATGGCACCAGTGAGGGT +CCTCGCCAATCATATATTCTAGAACATTCCTGGGCTTTTCGACCTGTATCATAAATCATC +CATACGAATCAGAATAGAACTAAGGAGTGTCAACCAGGAAGTTAAAGACTAAACCTACCT +TCCAGTGAAATTGGAGTTTAACAATAAGGAGAAAAAGGTTCCAGTCCCCACGTGTTAGGA +CATTGACCCCAGAGCCTCCTCAGAGAGCCAAAAATGTACTCCAAATGACCCTGTAATGAT +ATACTATGGTACTGTCACCAATGTCTTTTCAAAGTAGCTCCAAAGGAAGCTTTGCTCATG +GTGTAGCTTAAGCCCAGCTCTTTTTCTCCAGCCCTAAAAAAGGAAAATAAAAATACTGAA +GTCCTTTCATGGGCTTATTCCTAAAGCCCAAGATGCACAATAGTATAAGTGCTTTTTCTT +TATGAAAACATTAAAACAAAAATGATGCATCATTAAAGAGACTCCCTCAATTATGTTCTG +TCTTGCTTCCCCTCGAGGGAAACCGCCAAAGAAGGAGGAGGTTTATAAAGTAAATGACTA +GATGCAGATGTGAAATGACCTACCAGAGAGCTACTTCTGCTGATATGGGAAAGAAATACT +CTCCCTCCAGTCTCTACCAATAAACCAGCGGAGGTCTCCCCATTAGTCAGGGGACTTAGG +AAATCCCACTTGCTGGCCTATGGATGAACTGCCTGAAAAATATTTCCTCAGGTTCTCTAC +ATTTTCTTTAAGGTTTTGAATTCTGCACTGGAAAAAAGTTGAATTATTTTCTCCAATTCA +CACTTCATTATATTCAATATTGCAATTTTAATGAAGCCAAAGATCTAAGTGAGGATACCT +GCTCACATTCTGACTCTCTTCACAACCTTGGGGCGACAGAATGACATCTTGCAAATGAGG +ACACTGCGACACAAAGAATATAAGGAAACCTACTGAAAATCAAATACCTCTTAAATGTCA +GAACTGTAACTCACCAGAGATCTCCCTTCAAGTTTAGAGCTCTTCTCACTACACCACAAA +ATGGCTCTGAGGGTGAATTAATGCATTGTCACAGCTTAAGTCAGGAGAAAGAAACAACCA +CATCTGAACACTTCCTATTTAACCCAGCAGCCTGGTCCCATCCCAAAGGACAGACCTAGA +ATCAAAAAATTATGGAATAGTCATGTGAATTGGGGCTAGAAACTTCTGTAAGTGAACATC +TGGTTTGGTCCTTTGCCTTCAAGGAAATAACTTTATTGTTATGTCCATTTTCTTGGAATA +GGAGTTGAGTCCAAAGAGGATCAGTAAGTGCCCAGGGCTTATGGTTATTGATGAAGAGAC +AACCAAAGTTGAATCCTCAAAATTACTTTGTGGTATAGGAAACAGCCAGACTATTTTGAA +CTGACTTTGGGGTATAGGAAACAGCCAGACTATTTTGAACTGACTTTGGCCATGTTTCAG +GCAGCCCGGGAAGGGACATTTGCTCAGTAGGTGGAGTGGACTTCTGTGTAGACAATGAGG +TTTTAAATTTTAATTTAATTTATTTATTTTGAGAGAGGGATCCACTCTGTCACCCAGGCT +GGAGTGCAGTGGCGTGATCATAGCTCACTGTAGCCTTGAACTCCCAGATTTGAGTGATCC +TCCTGCCTCCACCTCCCAAGTAGCTAGAACTACAGGCATGTGCCACCATATCTGGCTAAT +TTTTTAATTTTCTGTAGAGACAAGGCCCTGCTATGTCACCTAGGCCTTGAACTCCTGACC +TCCCTCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACAACGCCTGGCCCAG +TGGAGTTTAAGGGGCGTCAGATTACTATTAAGAAACTGAGGCTGTGCACAGTGGCTCACG +CCTGTAATCCTAGCACTTTGGGAGGCCGAGGTGGGTGGATCACTTGAAGTGAGGAGTTCG +AGACTAGCCTGGCCAACACGGTGAAACCCCATCTCTACTAAAAATACAAAAATTAGCTGG +GCATGGTGGTGGATGCCTGTAATCCTAGCTACTCGGGAGGCTGAGGCAGGAGAATCACTT +GAACCCAGGAGGCAGAGGTTGCAGTGAGCTGAGATGGCACCACTGCACTCTAGCCTGGGC +GACAGAGCAAGATTCTGTCTCAAAAAAAGAAAAAGGAAAAGAAACTGAATATACAAATGG +ACATTGGTGGCTGGGTGCGATGGCTTACACCTATAATTCCAGCATTTTGGGAGGCTGAAG +CAGGAATTCCAGACAATGGCCAGACTGTATATGACCATAGAACCCTGTCCCACAACCTGT +GTCAACCAGATCAGAAAGCCAAACCATAGCCTATGCAGCAATCAACCCAGAATAGTTAGG +ACTTTGCCCATAACTGTCAGGTTTCCTATTTTTTGCCTATTTCCAACTCAGGACCAACCA +GAGGAAGCCAAATATGCTCCTCAAACTAATCATAGGAGATGCTCACTGCTAATTGGCCTG +CTCCCGGCTTCCTCATGCCAAGAACCCCTAATCAAATCATACTGGAAGCCTTTGGTGGTT +TTTTTGTTTTGTTTTTTCATTATAAATCTTCCCCTTCTCCTGGCTGCCTTTGAGTCTCTG +CCAAACACAAATGATGGTGGCTGACAACCTGGATAGAGCAGGCTCTGAATAAACAGCCTC +TGATTGTTCTCATTTGGGCATCTTTGTTTATTTCTACATTTTTCCTGGAGGTTCACAAGA +CACAGGCTGCACTTCCCGCTGCTGCAGACGCCAGCCTTCAGTCAGGTGTGGCTTCAGGAA +GGCCCCTTGTGTCTTGCTGCTTGTGGCCTCTGAGTCCATGATGACATGGTAAATCAGCAC +CAGGCTTACATTCTGCTCTTTTACATTGAGTTCTTTGGCCATTTATTCTGTTTGGTACCC +AGGTAATTTACTCATCCCCATTTGTTTGGCATCCTTCATGGAATCAGTTCCATTTCTTTT +TTTTTTTTTTTTTTTCTTTTTTTTCGAGATGGAGTCTTGCTCTATCACCCAGGCTGGAGT +GCAGTGGCATGATCTCAGCTCACTGCAATCTCCGCCTCCTGTGTTCAAGCGATTCTCCTG +CCTCAGCCTCCTGAGTTGCTGGGATTACAGGCGTGCACCACCATGACTGGCTAATTTTTG +TATTTTTAGTAGAGACGGGGGTTTCACCATGTTGGCCAGGCTGGTCTTGAACTCCTGACT +TCGTGATCCACCTGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCAC +CTGGCCCCCAATCAGTTCCATTTATTTTCATCCTTTTTGCTCTTGTTTGTGCTTTCTATT +TGTATTATGCTGTCTAAAAGGATTATTTGACATAAAAGGAGAATCAAAAGGTATAGCCCA +GACATAGGTCCTATTAGCCAATTTTTTTTAATCATCCTCACAGACTGGGGCATTTGTGGT +TCTCACCAAAATGGTAGCTATTCAGACAAATTTTGTTGTGGATTACCAATAAAACTGAAT +AAGTCACTTCTGTCTTTGTCATGATTTTTTCTCCCAGGAGCTTGGCTTTGATCCAGACAG +AATGCTGTTTTTCTCTCTGCTTTTCTGCATACTAGGGGGCACAGATTGTGGGGTCTGCAT +TCAGAGGTGGCCCACTGTCAGGTTGGGGCCTGAGACACAAAGTGCAAAACCATTACTTTT +AAGTAATTGTTGCCCCCTCTCCAGGGGTTGTGTAAGTCTAGGTCTTCTCCTCTTCCAGGA +AAAACTTCTTACTGGAACTCTCATTATAACCCTAATTCTTATGACTTCTTTCTAAATGCA +TGACTTCACCAAGGTCCTTCAATGGCCACTCTGGGGAAACATTTGACTTCAGCAGTATTG +TTCATTTGAGAGGAACCTTAGAAAAGAAGAGAAATAAACTTTCTCATGTCCAATGGGCAG +TAATTTTTTATTGGTATGTGGAGGCCTCTGAATGAAATTTGGATTCAATAATTGGTTCAC +TGAAAAACTAAATGGCCAAAGCTAATGAGGAATTTGACAAACTTAAGCAATAACAATCTA +GACTCATTTCCCTAGTATGCCTCCCCACTGCTTGTTCTCAGCTGCTTCCCTACATCCAGC +CCTCCCTCTTCTGCCTTATCCTTCTGATCTCTTTCCTTCTGCCCCTCCATAGACTCCTCC +CTCCGCTTCCCCCACATCCAGACTCCCCAACCTTTCCTAACAACTTTCCTAAGACCTGAA +AATATCAGTTGACTCTAAACATCAATCCTGCCCTTGAACCAGCATGCAACTGTAAAATTT +AAACCTTAGACCCTCTGAACTTTATGACCGTTCTCAGTACAACCATGTGAAACATCAACC +CCAATGATACATCATCAGTGGAAACCATAACAACACTACATTGAACTGGCCCAAGGGTCT +CACCCAGAAGATCACATTAGCTGCTTCTCCCCACCTTGAACCATGGCCAAATCCTATTAG +CTTCATCTAGATCCACTTATGCCTGAATGATAGTTCACTTCTGTTCTTCCCAGTTACGTG +AACCGGTAATTCCCTTTTTTACTTAAGCTACCTTGAGTTAAGTGTCTATCACTTGTAATC +AAAAGACTACTGATGGCTGAGCATGGTGGCTCACACCTGTAATACCAACAGTTTGGGAGA +CTGAGGTGGGAGGATCACTTGAGCCCAGGAATTTGAGACCAGCCCGGGAAACATAGGGAG +ACCCCACCCCTACAAAAAATTAAAAAATTAGTGCGGTGGTACGTGCCTGTGATCCCTACT +TGGGAGGCTGGTGTGGAAGGATCACTTGAGCCCAGGAGGTTGAGGCTGTAGTGAGCTGTG +ATTGTGCCACTGAACTCCAGCTTGAGTAACAGAGCAAGACCGTCTCAAAAAAAAAGAAAA +AAAAATGCCGATGAATATAGTAGAAACTTACAAGATGTGCTAAGAAGTATGATTTAAACC +TTGAAAGTCATGTGTAGTCACAGGTGAAGGGTTTTAATCACATGAGTGATATGGTCAGTC +TATTTGACTTTCTCTGATTGGTCGTGAATTAGAAGTGAGGACAAAAAAACAGAAGCTGGC +AGTCATTGACCCAGTCCTGACAGTTCTGTGCTGATTGCTGCAGAGGTTGTGATTTGGCTT +CCTGAACAGGTTGTGGGCCAGAGTTCTTCATCATAGATGTCTAATCATTATCTATTTCTT +TTTTTAATTTTTTAGACAGAGTCTCACTCTGTTGCCCAGCCTGGAGTGCAGCGGTGCATT +CTTAGCTCACTGCAACCTCCACCTCCCTGGTTCAAGTGATTCTCATGCCTCAGCCTCCTG +AGTAGCTGGATTACAGACACGCTCCACCATGCCTGGCTAATTTTTTATATTTGTAGTAGA +GACGGGGTTTCACCATGTTGCCAGGCTGGTCTCAAACTCCTGGCCTTAAGTGATGCACCC +ACCTTGGCCTCCCAAACTGTTGGGATTACAGGCATGAGCCACTGTGCCCAGCCGGATCAC +TATCTATTTCTATATTCAGTCTCTCAGTCCCATTTTGGTCTCTCACTTTTGAGAAGTTCC +CCAGCTCACAAAATGTTGGAAATCCAGGTTTTTACTTCTTGGAGATTGTCCAGTTGTCTC +CATAGCTAATTGAGAGATCTTGACTTGTTGTATCATCATTGTGATCGTCCAGCAAGAAAA +TGACCGAATGGATACATTTAAGACTCTGACGAGAATACAGTAGATCAGCATGATGACCAC +TATGACAAAAACAAGAGCAATTAACATTACCTGTAAAATGCTTCAAAACCAGGAATCCCA +ATTGCTCAACTCAGAACAAGAGAACACGATTGTGGGTGGTAGGAGGAGTATAGTTTTTGA +GTAAGAGGTAATGCCTTACGAGGTTCTTATACAATGCTTCCTGTAAAGCATTTCTCAGTC +ACTTGATGTAAAATTTGGTTTACCTCAGGTTAAACTCAAGTGGGCTTTTATTTTCCTTAG +CAACAATAAGGGCTGTAACTCTTTAGAATAGAAATGCTTCAACCCATCCTGAAAATAGAT +TCAAAATACCTAAAATATATTCAAATTCCATGGAGAGAATGAAATAGATGCAGGAAGACA +CTCAAAGGGCCCTTGAAGCTTTGGTTCCTGGCTATGCCCCACCCTTACAATTTTTCTAAA +ATTATGTTGTTGACAGGTGACACATGACCTGCAAATAACTTCAGCCATCTTTTAAAATTT +TCCCCATCAATGTTGATTTGAGATAGTAACCAATTTTTCTGTACCATAAGGAGTAGTTTC +ATGGAGAAATGTAGCTAATGTTCATTTGAAATCATCTGAGGCCACCAGCCTGGTTGGAAG +GATTAGAGATTATGTGTGTGAAGGGTGTAACCAGATTTTTTTCTATTCTTCCTCTTTAAA +ACAAGAAACTAAAAATTGATATTTTGTAATGGCCTCTTTGAGATTTATCTTTTGAGGGTT +TACTTGGAATCATAACCTTGATTAAGGCTTCTTATTAGGAAATGCTGCTGGAGCATTTCT +TTAGCTTACAAAGTCTCTCTTTCTACATGGGCCTCAACCTTTATAGTAGCTCCCTTTCCA +CATAGTAGGGCTGCACCTAAAGTTCCTTAATTTGTTCTTCATTTTTGATGGGGATTCCAT +CCGAGATCTTTTGTTTGCAAAGCATGCTCAAACCTAGTTGGTCAATTAGGTACTTCTGGT +ACCTAATTGACCAGCTCTACCAAGTGCGAAAGCTGTCTGCTGAGTTTTATTTTATTTATT +ATTATTATTTTTAAATTGACAAGCAAAACTTAAATATATTTATGATGTACAACGTGAAGT +TTTGGTATATGTAAGATATTTAACATATGCATTATTTCACACACTTATTTCTTTAGTGAG +AACACTTCATTGTCTGGATGAAATTGCTGTATGTTCTCAGTCAGTAGTAATGTCTGTATT +GCAGGAGGAAACATGAGGTCAAATAGGGAGCCTAGAACTAGTTCAGGAGAAGTATTGACA +AGTTTTGCAGTGACAGCTATTGCCCTATAATAAGTGCGATAAACTTCTGTGACCAGGTCA +AGGATGAGGCTGCAGTAAGCAATGGGTTTTGAAGGTTCCCATGGAGTTAAAATCCCAAGG +GTATGTCTAGATTGCTCATGCCACGGTTACATTTGCACATTCCTTAGCTCTCAAATGTTA +TTGAAAAATATTTTTTACATTATCCCAAATACACATATTCTCCACGTTTGAGTTATGGTC +CAGTTAGTTTTTTTAATTTTTATTTTATTTTAATTTTTTTTTTTTGGAGATGAGGTCTCC +CTCTGTGACCCAGGCTGGAGTGCAGAGGCATGATCTAGGCTCACTTCAGCCTCTGCCTCC +CGGGCTCAAGCAAACCTTCAACCTTAGCCTCCTGAGTAGCTGGGACTACAGGCATGCACC +ACCATACCTGACTAATTTTTGTATTTTTTGTAGTGACGAGGTCTCACTATATTGCCCAGG +CTGGTCTCAAACTCCTGGGCTCAAGCAATCCACCTACATCAGCCTCCCTCTCGAAGTGCT +GGGATTACAGGTGTGAGCCACTGCACCAGGCCATCCAATCAATTCTTATGGGAAGTATTT +CAGGTATGGCTATTAGGAGACTTCACCCAACTTTTGGGGCTATTTTCTGACCTTCCGGTT +TATTGTGAAAGAAGAATCCTCAGTACCTTGCTGGATAAGTTCAATTGGCTTTTTCTGTCC +AGGATTTAGCATCTGAGTTTCTGATCAACATTTGTATAATTTGATATAGCTCAGGTAACC +CTGGGGTCATATGTGCCCAGGTCAACATCAACTCAGAGACTAACAAGGTGAGAAGAGCCC +AATGAGCTTAGTTGCTCAAATGGAAAGAGTTCAATCAAGAATGGTTATTCAGTCTGGGCA +CGGTGGCTCATGCCTGTAATCCCAGCACTTCTGGGAGGCCAAGGCAGGCAGATCGCTTGA +GGCCAGGAGTTCAAGACCAGCCTGGCCAACATGGCAAAACTCCATCTGTACTAAAAATAC +AAAAATTAGCCGTGCATGGTGGTGCATGCCCTGTAATCTCAGCTATTCAGGAGGCTGAGG +TGGGAAGATCACTTGAGTCCAGGTGGTAGAGGTTGCAGTGAGCCAAGATCGTGCCACTGC +ACTCCAGCCTGGGTGACAGAGCAAGACTGTCTCAAAAAAAAAAAAAAAGAATGGTTCATT +CGCGAATTCAGCCAGGGCCAGGTACAGTGGCACTGCCTATAATCTGAGCACTTTGGGAGG +CCGAGGCAGGAGGATCACTTGAGGCTAGAAGTTTGAGACCAGTCTGGGCAACAGAGCAAA +ACCTCGTCCCTACAAATAATTTAAAAATGAGCTGGACATAGTGGTGTGTACCTGTGATCC +CAGCTACTCAGGAGGCTGAGGTGGGAAGATCACTTGAGTTCAGGTGGTGGAGGCTGCAGT +GAGCCATGATTGCACCACTGCACTCCAGCATGGGCAACAGAGCGAGACCCCATTTCAAAA +ATTAAAAAAAAAAAAGATTCAGGTGCCTTGAACTCTGGTTTCCTCTCCTGTAATGCCACC +ATCTTACATGAAGGCCCTCTTTGCATCACCTGGTAGGAATTGAGATTCAGGCTACTGAAA +AAAGTCAATACTAGGGCTACTGCTTTTTCTATGAGTAATAAAGTCCTTTGATTTTGGAAT +GTTGTGACAATATCCGTAAAATAGGCAGTCTAATTTGTTAGCTTGCAAGTAGAATAAAAT +CTCACACCCTTCACAGCTCTTAGGCATCATATTATTACAATTCTAGATTTCCTTTTCCTG +CATTCAATTATGATTCTTAGGCAGAATGTCGGTAGTAAGAAAGGTACTATTTATCCATTG +AATTGGAGGAACAAGTAGGGCATCCCAGTGGAGGTGACCAATAGAAAGTTGGATATTGCC +ATTTCTGGCATATGAGTGGCACTAAAGACAAGGATTTGTGAGAGATAACCCAGAAAAAAC +ACGTAACATATATGATATGCTGCAGTCATCTCACATCTGCTTAACATCAGTGAACTGCAT +GCATATCTTTCCAATGCTATGTTCAGTGACTTCATCTTGGTATCTTGAGATTGGCCACAG +TGAGAGTATTTACACCATGGAAATTAACAAATGCTACAAATCAAGGCTTCCTCCACCCCC +ATGAGAGCTAATAGTCATCAACATGCTACAAGAGGATGGTGTAGCTGATACATGATGGCA +GCAACTTCCATCATCTATTTTCTTCTTCTGTGAAATGTGAAGAATAATTGTGTCTATGAC +ATGGGATTTTTTAGAGGATTAAATGAGAGACTTTGTAAAACATGTACAATAGTAGTCTTG +GTACATATTGTATCTAATCAAATCTGAGATGCTACCAAATTGAAAATTTGGCATTCTTTT +AGGTCATACTGCCAAGAAAGAAGAAGCAGTTAATTAAATCATGTGTTCTTGCCACATTGA +TTTTAAGACACATATCAATTTCAGAGATGGTAAAATGTGAAAAAAAACTCGGTCTGAAAT +GAATAAAGTAAGTAGCATACTTTTAACACGCTTCACTAATGGTATATTATCACTTTGAGT +AGCTAAAATGTGTGTATGTGTAGTAAAAAAATCATTTGTTTCAGGTTCTACAATTTTAAA +TCACCAATATAATCAAAATTTCTATCCATAAAAATGCTCAGAAATCAGATGGTTTGCATT +AATGAATGCTCAGCATACAAATAGGTGCGAAAGAAAAAATTGGAAATATGACTTTTTTTT +CAAAATAAAACCAGACACAAAATTCAGTGAGTTGTGAATTTCAAATAGTTAAAAACAACA +ACAACGACAACAACGAAGATTTAAACATACAAGAAGCATTGGTGGGGCACAAAAATAACA +CCTGTAATCATAAACAAGTGAACGCAAAATTAGTTCTCTAAACAATTTATCCACACCTTA +GAAAAACGTGAACTTACATGAGAAGCAAAGTACTAAATGTGCTTATTTAACTAATTATAT +ATATGTTCTAGAAAAAAAGATAGGGGACTGGTAAATAATGACAAAGGAAGGGAATTGGCT +ACAGTGTAATTAGCTCAAGGCTGTGGGCATACATTTATATTGTATAAAGAAAAATTCCTG +GAAACAAATGAATCCAAGCTACCAAACTTGGAGAGAGAAGAGAAACTACTATGTTTGCAC +AAAATAACTTCAAAGGGAAACAGGGCTTATTTTCTTTTACACCATTGCAACTAAAAAATA +ATAGAAGAGCCTACTATAATTAAGTGAAGACTTTACAGCTATTACAGAGAACACAGAGTT +TTAAGCAGGCTATAAAACACTATGACTTTTCTGTGAAGAGGGAGGTATGGGAAAAAATGA +AAAACAAAACCAAGCCCATAATGACTTTCAGAAAAACTTAACTCTCAACCCCTTGGAAGC +AATCTCTAGTTCCCTCTGGGGAAGAAGCCTTCTCAGCATAAGAAGATACAGCTTTGACTC +CAGGGCTCAGCCCACTGCAAGTGGGTTCGTTTGCCTAAATGCATACTTGCCAACTGACCA +CAGCTGAGGCACTCTGCTGGAAATAGTTTGCAAATCAGTTTCCATACCATAAGGAGTAAC +CACTCCCCAAGACCAGTGTAATGGATGTGGTATAAAATTTTGAAGCAGAGTATGTGTTTC +TGGCATGTCATTTGGATGTGAGCCTTGGGCAAAGCAGTCTGTGAACCTCAGGATTTTTTT +TTGCTTGTTTGTTTGTTTGTTTCTTCAGACAGGGTTTTGCTCTGTCACCCACATTAGAGT +GCAGTGGCATGAACACGGTTCACAGCAGTCTTGACCTCCTGGGCTCAAAAGTGATCCTAC +CGCCTAATTCTCCTGAGTAGCTGGGACCAGGAGTACGTGCCACCATGGCTGGCTAATTTT +TTTATTTTTTAAGGAGATGGGGTCTCATCATGTTGTCCTGGCTGGTCTCGAATTCCTGGG +TTTGTGTGAGCCTCCCATCTCAGCCTCCCAAAGTGCTGGGATTATAGGCGTGAGCCACAG +TGCTGGGCCAAACTTCAGAGTTCTTATCAACAGTAAACAATAGTGAGACTTGCCTGTCAG +GAGTCATAAGACTCCTGAAAAGATCAAGATATATGTTTTAAAAATTATTTTAAAACTGTA +AAAATGCTTTATAATAAGAAATGAATTATTATTACTACTACCGCTACTACTCTTATTTGC +CCTGCAAATAGCGTATCAATCACCATAGCACTGTGTGATGAACTTGGGACACGATTCTGC +ACAAAATGATAGTAAAGGGACATTAAGAATGCTTTGGGAGGCTGAGGCAGGAGGATTGCT +TGAGCCCCAGCAGTTTGAGATCAGCCTGGGCAACATAGTGAGACCCTGTCTCTGCAAAGA +AAATAACTTTTTTTTTTAAAATTAGCTGGTGCAGTGGCATGGGCCCATGGCCCCAGCTGC +TTGGGAGACTGAGGTGGGAAGGTTGCTTGAGACCAGGAGTTTGAGGGTGCAGTGAGCTAC +GATCAAGCCACCACACTCCAGACTGAGCAACAGAGCAAGACCCTGACTCTGTAAAAAACA +TTTTTTTAAAGATATATTAATATGTCTTAAAAAAAAGAAACAGGTGTTTCAAGATAGAAG +TTATGCTTCATTTTCTATTATAAAGTCTAAAGGAATTCCAGAAAAATCATGAGCTTTTAA +TTCAGGCAGACAGGAATTTGAATGTGGACTTTACATTTTATTAGCTGTGTGATGGTGGGC +AGGTTACTTAAGCTCTCTGAGTTTAGGGAATCCTACCTCATAGGCTTGTTGCAGACATTC +CATTGTGTAAAGTGTGTAGCTCAATGAATTCCAGGTCCTCCCTCTGCTCTTAGATACATT +ACCTTTTTTCCTTACATTTTTGTGTGGAGCTTTGGAAGAGCTCTGTGGGGTTATGGGTGA +TGTTTTATGTAACCCTGTCCCTCTTTTATTTTTTTTTCTTTTTTGAGATGGAGTTTCACT +CTTTGTTGCCCGGGGCTGGAGTGCAGTGGTGCAATCTCGGCTCACTGCAACCTCCGCCTC +CTGGGTTGAAACGATTCTCCTGTCCTGTCTCAGCCTCCCGAGTAACTGGGATTACAGGCT +CCTACCACCACTCCTGGCTAATTTTTGTATTTTTAGTAGAGATAGGGTTTCACCATGTTG +GCCAGGCTGGTCTCAAACTCCTGACCTCAGGTGATCCACCTGCCTTGGCCTCCCAAAGAG +CTGGGATTACAGGCGTGAGCCATCACGCCTGCCCTCATTTTGTTTTCGACACAGCTCAGC +ATAAAGCAGTCAAGAGAAACAGTTGCTTTTCTGCTATTTGAGACTACAACATATAAATTA +GAGATGAGACCGAAAATCTGCAGTTATGTTTTATGTCACTAGAGCCAAAAGCTTCATTAA +CTGATAATGGCATTTATTCCACACTTTCTGTGTGTTAGGCACTGTGTTTTGTTTTGTTGT +TGTTTTTCATGAGACAGGGACTATATTACCAACAGTGGTCTTGAACACCTGGGCTCAAGC +AATCCTCCTGCCCCAGCCTGCTGAATAGCTGGGATTACAGGCACGCACCAGCTCAGTATG +AAGTCTTTTTTTTTTTTTTTTTTTTTTTTTTGAGACAGAGTCTTGCTCTGTCATCCAGGC +TGGGGTACAGTGGCCCAATCTCAGTTCACTGCAACCTCCACCTCCCAGGTTCAAGCGATT +CTCCTGCCTCAGCCTCCCAAGTTGCTAGGATTACAGGCATGTGCCACCACACCCAGCTAT +TTTTTGTATTTTTAGTAGAGACAGGGTTTCACCATGTTTGCCAGGCTGGTCTCGAACTCC +TGACCTCAGGTGATCCACTCGCCTTGGCCTCCCAGAGTGCTAGGATAACAGCATGAGCCA +CTACGCCCAACCCAGTAGGAAGTCTTAAATGGCTGTTTTCATTTAATCTGTACATAACCC +TGCAAGGAAGTATTAATGACCTGTATTCATTCCCCATTGCTGCTGTAACAAATCACCACA +CAGTTAGTGACTGAAAGCACCGCAAATGTATTCTGTTGAAGGTCTGGAGATCAGAAGTCT +AAAATGGATCTGCAGGGTATGGCATGGCCTTCCTGGAGGCTGTAGGAGAGACTGTTTCCT +TGCCTGATCTAGCTTCTAGAGAATACTCACCTCCCTTGGCTTGTGGGCCCTGCATCACTC +TGACCTGAGCTTCCGTCATTGCATTTCCTGTCAGTCTCCTGCCTCCCTGTTTGCTGTATT +ATAAGAACACCTGTGGCCGGGCGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGG +CCAAGGCGGGTGGATCACGAGGTCAGGAGATCGAGACCATCCCGGCCAACATGGTGAAAC +CCCGTCTCTACTAAAAATACAAAAAATTAGCCGGGCGTGGTGGTGGGGGCCTGTAGTCCC +AGCTACTCAGGAGGCTGAGGCAGGAGAATGGCGTGAACCCGAGAGGCGGAGGTTGCAGTG +AGCCGAGATCGCACCACTGCACTCCAGCCTGGGTGACAGAGCGAGACTCCATCTCAAAAA +AAAAAAAAAAAAAAAAAAAAGAACCGTTGTGATTACACTAAACCCTCTCAGATAATCCAG +GATAAGCTCCCATCTTAAAATCCTTAATTCTTAATCATGTCTGCAAAGTCCTTAATTAAA +ACTGCAAAATATCTTGCCATGCAAAGTAACATATGTACAGGCTTTGGGAATCCTGTATGT +TAAATAGGCACGTGTGCTAGACAGAATGATGACCTGCCTCCACTTCCCAAAGATGTCCAT +GGCTTTGGGAAGGGGGTGCAGGTCATCATTCTGCCTAGCACACGTGCCTATTTAACATAT +GAGGGAATTCAGGCTTGCACATGGTGCATGAACACTCAAGTTGCACGCTTTGTAAATTAG +AACCTAAGTTCTGGGTCTTGAGCCCAGATGGCAGCCTCCATCCTTTACTACATGAGCCTT +GGGCCCAGAAGCACACACTGCCAATTTGCATGAACAGATGTGTTTTGTTTTGGGCATGGT +TATTACACTGATGGTGGTGACCACATTTGATAAACGTGCATCAGACATAGATTTATTTTG +TACATTGTCTCAAGCTCCAGCAGCCATACTTATTACCTATTCTCAGACTGATCACCTTCA +AGACAAATTTAGTACCTACTTGGCATTACACCAGCTGTTACAGATAATTAAACAAAGACC +CAATTCTTTATCCCTGAGGGAATTTCTAAGACAAACCAGTATGAAAATGCAAAACTACAT +GTGTTGGAATAAAGACCAGAGGGGACTGCTGCCCCAACTGAGAAGGACAGTTAACACATT +TATTAATTTGAAACTGTTTTATGTGTCTTTTGCCAAGGGGTTAATAACTTACTTCGGTTA +CTATATCTTATTTATTATTATTACTTCAGTGAAAATACTGATGGAGATTGATTTCTTGCT +TTAAATATTTAAAGCGTGGAGTTTAAGCCCACTTACAGGAATGTAAGAAACAATGACAAA +CTCTGCTCAAGCAAATACCTCTAATTTTTCTCACTAGAAATTGGTGAAAACATTTCACCA +GCACTGGAGTAGAGAGGGACATGTGAACAAAGTTCAAACCGCACTTGCAGTTGAAAGTGG +ATGAAATACATGCAGACATGGATGAAAATATGCCCTTTGGCCTGGAACTCTAAAATCACG +TGTCACTGGGCATGGTGGCTCACACCTGTAATCTCAGCACTTTGGGAGGCCGAGGTGGGT +AGATCACTTGAGGCCAGGAGGTCGAGATCAGCCTGGCCAACATGAGGAAATCCCGTTTCT +ACTAAAAATACAAAAATTAGCCGGGTGTGGTGATGGGCGCCTGTAATCCCAGCTACTTGG +GAGGTTGAGGCAGGAGAATCGCTTGAACCTGGGAGGTGGAGGTTGCGGTGAGCTGAGATT +GTGCCAACACACTCCAGCCTGGGTGACAGAGCGAGACTCCCACTCAAAAAAAAAAAAAAA +AAAAAAAAAGCACATGTCACCATGTCACTCGGGGAAACAACAAACAACAGAACCTTATGT +CAGGGAGAAAAAGTAAGCCCTTAGAAACCCTGCAGGTCCCTGTCAATGTCAGTGGGCTGC +CCTGTTTTTGCTGATAGTGCCATGTTAGGAAGATTCAGCCCTGGAAAAATACCATATCTC +AGAGAAGGAAGCAGTCAGGGAAGGCCATGTGTAAAAAAGAGAAAGTACTCCATCTGTTGT +GCAGTTCAAATACTGAGGCCATTATTTGTTCATCTGGTTGATTCGAAGCTTCAGTCTCTC +TCTGTGGCTTTCCTTCTTGAGCTCCTTCATGTTTATGGCTTGAAAAATAATTAATGTCCT +GCTTTTAACTCCAACATGATGTTCCTGTTTATATACATCCCACACTTCAATTCTATACTC +ATAATTCAATTAAGGAATTTATGTCTGGTACAATTTTTGCTTAGCTCTTCATATATTTCA +ATAGATGTAATATATAATCTACAGAAAAATAGAGAAGTGATGTAACAAACAGCTTTACTT +TGGATGATTACCTTGCGTATCTTGCCAGATCTTAAATGTCCATCTTTCAATCCTTTCTCT +ATATGACTGGGATAAAGTGTTCCAAGAGTATTAGCTAATGGCCCACTGGCTTCACTTAAT +TTCCTTTGAGAAGATTTATCTTTATTTGTGTCTGTACCAGCAACTGCGTAGTGCCCACAC +TGGTTTGTGCAGCACTCTTCTCTTACGCACCATCGACACGATGAGTAATGAACAAAATGT +TATTTTTCCTACATGCTTCACTGCTGAAAATAAAATGTCTGTTAGACATTTCCTGAAGAT +TTCTTTTACTGTCAGAAATGATTAAGTGATGGAAATTTGCTAATCAATACAAATCATATA +GGAGAAACTTTATAAAATATTTTTGCTATTCTGTTTGTGGACATTTGGTCAGGAATGAGA +GCTTTAAAATCTAAATATTGATCTAGTCCACTGAGCTGATTAAACAATGCATTGGCCATT +CAGGAGGAATCCACTGAGAGCTGATGTGGGGTGCGGGGGATTTGCCTCCTCCATAACAGA +GGAAAAATCTTCAGTGTGACACTTTTTTTTTTTTTTTTTTTTTGAGACGGAGTCTCGCTC +TGTCACCCAGGCTGGAGTGCAGTGGCGCGATCTCCGCTCACTGCAAGCTCCGCCTCCCGG +GTTCACGGCATTCTCCCGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCGCCCGCCACC +GCTCCCGGCTAATTTTTTGTATTTTTAGTAGAGAAGGGGTTTCACCGTGCTAGCCAGGAT +GGTCTCGATCTCCTGACCTCGTGATCCACCCACCTCGGCCTCCCAAAGTGCTGGGATTAC +AGGCGTGAGCCACTGCGCCCGGCATTTTTTTTTTTTTTTTTTAAATCAGGTCTCACTCTG +TCGCCCAGGCTGAAGTGCAGTGGCATGATCCCGGCTAACTGCAACCTCCGCCTCTGAGCT +CAAGCAATTCTCCTACCTCAGCCTTCTGAGTAGCTGGGACTACATGCATGCACCACCACA +CCCAGCTAATTTTTGTATTTTGTAGAGACAGGGTTTTGCCATGTTGCCCAGGCTTGTCTG +GAACTCCTGAGCTCAAGCAGTCCTCTCGCTTCAGCTGCCAAAAGTACTAGGATTACAGGC +ATGAGCCACTACGCTCGTCCTAATGTCTTTATTTTCCTTATTAATGTCCTTCCATGTAAA +TGAATATATTTTATATAGCTTCACAGGCAATATAACCTATATAGTTTTGTCGTCTATAAA +ACAAGGAAAATAATACTACCTACTTAGAAAGTTGTTGTAGGTATGAATTTTAAAATTTCT +TTTCTTTTTGAGGCAGTCTCACCCCGTCGCCCAGGCTAGAGTGCAGTGGTGTGATCTTAG +TTCACTGCAACCTCCGCCTCCTGGGTTCAAACGATTCTCACACCTCAGCCTCCCAAGTAG +CTGGGATTACAGGCATGTGCCACCACACCTGGCTAGTTTTTTTGTATTTTTAACTGAGAC +AGGGTTTCACCATGTTGGCCAGGCTTGAATTTTAAATTTTCAAGCAAAGAATACAGCTTG +TTGCCTGGCATACAGTAAGAACTCAATAAATGTTACAATTTTTATCAGCTACTGCCATAA +CTTTTATTTTGGCGAGGTATGTATTATATTAAGTAAAGTGTTAAATGACAGCAGTATCAA +AACACTCTCTCTTTTTTTTTTTTTTTTTTTTTTTGAGACGGAGTCTCGCTCTGTCGCCCA +GGCCGGACTGCAGACTGCAGTGGCGCAATCTCGGCTCACAGCAACCTCCGCCTCCCAGGT +TCAAGCGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGCACTACAGGTGCGTGCCACCAT +GCCCAGCTAATTTTTGTATTTTTAGTAGAGACAGGATTTCACCATGTTGGCCAGGATGGT +CTGGATCTCTTGACCTGGTGATCCGCCGGCCTCAGCCTCTCAAAGTGCTGGGATGACAGG +CGTGAGCCACCACGCCCAGCCACTTTTTTTTCTTTTAAGTCTTGCTCTGTTGCCTAAGCT +GGAGTGCTGTGGGACGATCCTAGCTCACTATAACCTAGAACTCCTGGGCTCAAGGGATCC +TCCCACCTCAGCCTGCTGAGTAGCTAGGACTACAGATGCATGCCACCATGCCCAGCTAAT +TTTTTAAAAAATTTTTCATAGAGCAGGAGTTTTGCTATGTTATCTAGGCTGGTTTCAAAC +TCCTGGCCTTAAGCAATCCTTCTGTCTTGGCCTCCCAAAGTTCTGGGATTACAGGCATGA +GCCACCACACCCTGCATCAAAACACTCTTTGAACTCGTGCCTTTTTACTATACCACTTAT +ATTTTTATAATTGAAAAAAAAAAAACAGAACTAAAATACTTAACAAGCCTGATGGAAGTG +TTAGAGTAAAAATTAAATTAAAAAGATCCTCAAATGATGATACAATTTTCCATTAATTTG +TCTGGGTAGTCAGTCATGAACTGTTGATTGAATGTCCGCTAAGTGCAAGCTAGAACCAGT +GGAATTGGAGCAGGCAAAGTGTGTAAACTGAACACAGCAAGAAGCAGTGGGGCTCCAGCA +TCCTCATGATATAGTCTAGTTTACTTTGGTGGGATTAAGAAATCCTGCTTAAATGATAAA +TCTTCTCACTAATCAGTAATATACCTTTCAACCCTAGCCATAGAGTTATTTTCCACAGGT +TTTAACAAGGAACAAAGATGTCTCTGATGTGCTTTTCATGACTACAGTTTCTATGCCTCA +AGGCTTACTACAGTCGAGGAAAATCTTTCCTTCCTTTCATTCTCTCAAGGCTTCAAGCCT +TCAAGCCTTTGAAATGAATCAATACTGAATTCATTGACTTAGGCATTCCAACAAAACAAA +GAAACTTAACAGACTAGGAAAAGCATTAAAAACATTTGGAATACTTCCACCCTCCCCGCC +CCCGCCTCCACTTTTTTCCTATTGGAATTGCAAGAGTATTTTCACTGTAGAATTGCCATT +ACGGCCGGGCGCGGTGGCTCAAGCCTGTAATCCCACCACTTTGGGAGGCCGAGGCGGGTG +GATCGCGAGGTCAGGAGATCGAGACCATCCTGGCTAACACGGTGAAACCCTGTCTTTACT +AAAAATACAAAAAACTTAGTCGGGCGTGGCAGCGTGCTCCTGTAGTCCCAGCTACTCGGG +TGGCTGAGCCAGGAGAATGGCGTGAGCCCGGAAGGCGGAGCTTGGAGTGAGCTGAGATCC +CGCCACTGCACTCCAGCCTGGGCGGCAGAGCGAGACTCCGTCTCAAAAAAAAAAAAAAAA +AAAAAAAAAAAAAGAATTGCCATTGCTTTGCTTGCAAACAAATGAAAAGCCATTGCTATG +GTTTGACGAATGATTCCTAAATCAGGCAGCCTTTTGAGCATCAGTAGGCTCAGAGACTCC +AGTGCAGCCACGTGGTGGAAGAACATGTATGGACAGAAAAAGGAAAAAAAAGAAAGAACA +GGGAAGGGAAGGGAAGGGAAAGGGGAGGGGAGGGGAGGGGAGAAGTGGAGGGGAGGGGAA +GGGGGAGGGGGACCATTGCTACGGTTTGAATGGGTGCCCTCCAAAATTTAGGTGTTGCCA +ATGTGATAGTATTAAGAAGTGGGACCTCTAAGAGGTGATTAGGCCGTAAGAGCTGCTCCA +TCTTTAATGGATTTAAGGTCGTTTAAAAAGAGGCTTCATGCAGCATTTCGCTAGCTTGCC +TTTCTGCTTTCTGTGTGAGGATATAGCAAGAAGGCCCTCACCAGACCAAATGCCTTGATT +TTGGACTTTCCAGCCTCTAGCACTGTAAGAATAAATGACTGTTCTTTATAAATTACCCTG +TTATAGCAGCACAAAATAGGCTGTGACAACTGTCAATCATCCCCTTCCTAAATTCATTTT +ATAAATAACAAGTTAGCATTTCACCAATAGATACTAGTTTTTTAAAAAGAAGGTGATAAA +ATGGTCATAAAATGACCATACTGGAGCTTCACTGCTTCTTGCTGTGTTTGGATTGCACGC +TTTGCCTGCTCTAATTCCACTGGTTCTATCTTGCACTTAGTGGACATTCAATAAATAGTT +CATGACTGCCTAGATGGACAAATTAATGGGAGACTATAAAATTCATTTAAAGATATTTCA +ACATAATTTTATATATCCTGCTTTCACTCTAAGTTATGAATAGTTTTCATGCAACACATA +TACTCAAGTATATTACAAGTTAAATAATATCTGAGTAATTAAAAATATTTAATGAGCTTT +CCTGAATATGCAAAACAAACACTTTCACTTTTGCTGTGAGCTTTTAAGCTGAAAAGTTTA +TAGCATTTCAGAAAGAAAAATCAGGATAAAATAAGCATATATCTATGGTATTATGTACTT +AATAGCATCTGGTTGCTAAATATTTTCTTTTGGCTTCTTGATCAATAAACAGCAGGAAGC +TCTGGCTGTCCATTAGAATGCTTTCAGTAGCAAGACAGAAAGCCCAACTCAAACTATTTA +ATTATAACAGAACTGGAAAGTTTAAAGGTAGAGCAGCCTTCAGAATGATTTGATTCAGTA +GCTCTGTGATAGCAAAGAACCTAGTTAGGGAGACAATCAAAATGTCTCACTTTTTCCTCT +GGTCATACTGTTATAATACACACAACCATATAATGATACATCCTGTCTAGAACTAAGCCT +ACCAATAGATGGTATGATTTCCAACAAACCCTTAGACCCTCTTAGCCTCAAAAATCTCTA +TTCTATCAACTGTTCTCCAGAATAATATTACCTTCACAATACCTTGTTCAAAGAAATTCT +TCATGGTAATGGGAACAAATAATTTGGTATCCGAGTATTACTGCTACTTCCACTGCATAG +TTATAAGACATAGGGCAAACCATTGACTTCAATAATTTTCAGCTTCCCAAACTGTAAAAT +GAAGCTTACAAATAATGTGCTCCTTGATTGTATAAACAATCTCTAACAAAATCCTACAAC +AAACATTTTACTGAATTAGAACACCTTAGGAGTGGTCCTTGTATGTCAGGAGCAAGCACA +TTTGTTTACCTGTTTTCTGTAATTGCTTTTGCACTACAATGGCAGAGTAGAGAAGCTGCA +ACAGAGTCTATATAACTCTCAAAGCCCAAACCATTTACTGTCTGGCAACCTTACAGAAAA +AGTTAGCCAACCCCTGCCCTGCAAAAGGAAGGCTTTCATACCAGAGTTGCAGCTTCACAA +GAAGCCTTGTTTTTTTTGAATCATTGCCCACCACATATCTTGGGAAACAGGGAAAGCAAC +TTTGGAGTATTCATATTTTTACCCAGAGGGTGTCTGCATCCCAATAGAAACAGATGGCCA +TTTTAACTCAGATCATTTGAGGAGGGTTTATTTACAAAGGTTTGAATTCAGGAGAATCAT +GGAGATTACTACCTGAAGTAGGGTTTGGGGTGCAGTTACCAGGAACAGGGAGAAGAGAAC +ATTGTAGAGTTAGAGTTCCTGAGAAAAATGGGGTCTTCCAGTCGAGGGACACAGCCAATT +CAAAGACACCTGGTGGGGAAGGAGGCAAGGTGATAAATACCCCGACTTTCGTCTCCTCTT +TCTTCTTTTTTTCTTACTGAGGCTCTGCACTGGCTGAACCCAATCAGAATGACAGTGGAC +TTGGCAATGATCATTATGGTCCATACCATTCAGGCTCCTGGGCAGAGAGCAACACAAAGA +AGGCTGGAACTGGATATGGTGGGGCAAATAGAAGCTATTTGGCATAGAGAGCAATCTTGG +AGGTATCACTGAGCAAAATGAAGAAATGTAACGGTAAAACCGATTGTCACTCAGGCTCCT +CCTAAAAGGTTCCTAGATGGAATGACACACTGGTAGTAGTGAACACACCTACCATCCAGA +TCTTGGTTTCTAAATACCATTGTCACATAAAAAGAACCAGTACTCCTTGGAAAAATGGCT +TTCTCTATGGCTGTGACAGGGAAAATACAAGATGACCTGGGCGTATCTTGTTTTGCCAGA +AAGTAAGGAAGAGCTCAAAGACTGAAGGGTGCCAGGTATGGTGGTGTGTGCCCATGGTTC +CAACTACTCAGGAGACTAAGGCAGGAGGATGACTGAGTCCAGGAGTTCTGAGTTGTAGTG +CACTATGCCAATCAGGTGACTGTGCTAAGTTTAACATCAATATGGTGACCTCTTGGAGCA +GAGGACCACCAGGTTACATAAGGAGGGGTGAACTGGCTCAGACTAGAAATAGACCAGATC +AAAATTTCCTTGCTGATTAGTAGTGGGATGGTATCTGTGAATAACCACTGCATTCCAGCC +TGGGCAACATGGCAAGACCCTGTGTCTAAAAGGAAAACAAAAAGATTTAAGGGTACATGT +CAAAAGGACATAGGAGTCAGTTTGAAGAAATTCCCACTGGCCAAATCCGGGGCAATTTTG +GACAATATTTAACTATTTGTAGTAATAGTTACAGATTGAGGCTGGGTGCAGTGGCTTCCG +CCTGTAATCCCAGCACTTTGGGAGGCTGAGGCAGGTGGATCACAAGGTCAGGAGTTCGAG +ACCAGCCTGGCCAACATAGTGAAACCCCGTCTCTACTAAAAATACAAAAAATTAGCTGGG +GGTGATGGCATGTGCCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATTGCTTG +AACCCAGGAGGTGGAGGTTGCAGTGAGCCAAGATTGTGCCATTGCACTACAGCCTGGGCA +ACAGTGCGAGACACCATCTCAAAAAAAAAAAAAAAAAGTGTTACAGATTAAACCTCAGAG +TAAAGTAAATGTATGTGAACACATAGTGATATAAATTTTAAAATGAATGAATAAATGGGG +AGAATGTTCTACCTTATAGTAAAAGTATTAAGGCATATTACTACAAAGTACTAATTAACT +ATTAATCAGTGAACACAATGTAATCATTAATTAATTTTATAGTGAAGAAACTTGGTGAAC +ACATTAACCAAGTGATAAATATTATCATCAGGGCTGGACATGGTGGTTTATGCCTGTAAT +CCTAGCACTTTTGGAGGCTTATGCCTGTAATCCTAGCACTTTTGGAGGCCAAGACAGGCA +GATCGCTTGAGACCAGGAGTTTGAGGCCAGTCTGGGCAACATGGAGAAACCTCATCCCTG +CAAAAAATACAAAAATTATCCAGGTGTGGTGGTGTGCACCTGTAGTCCCAGCTACTTGGG +AGGCTGACATGGGAGGGTCACCTGAGCCTGGGGAGGTTGAGGCTGCAGTGAGACATGATT +GTACCACTGTACTCCAGCCCGGGCAACAGAGTAAGACCCTGTCTCAAAAAAAAAAAAAAA +GTTATCATCAATAATGAAGTACAAGTCCTGTGCCTCCGATGTAATGTAATGAGAAAACCA +CATCATTACTTCTATGGTATTCCTTGCAATAAAAAAGCATACATCCTGAAGAAACATCAG +ACTTACCCAAACCAGGGGATAATTAAATGGTTAGTAGCCTGTACTCTAAAAATGACAAGG +TTTTTTTTTGTTTGTTTCTGTTTTTTGTTTTTTTGAGACGGCGTCTTGCTCTGTCACCCA +GGCTAGAGTGCATTGGCGCTATCTCAGCTTACTGCAACCTCCGTCTCCTGGTTCAAGCGA +TTCTCCTGCCTCAGCCTCCCAAGTAGCACCACCATACCTGGCTAATTTTCGTATTTTTAG +TAGAGATGGTGTTTTACCATGTTGGCCAGGGTGCTCTCCAACTCATGACCTCAGGTGATA +CGTCCACCTCGGCCTCCCAAAGTGCTGGGATTACAAGCATGAGCCACCGTGCCTGGCATA +AAAATGACAGGTTAATAAGAAACAAAGAAAGTCTGAGAAACAGAACCTGACTGAAGGAAA +CTAAATGGATATCATAACAGTCCCTGGGACTGCTCAGGGACTGTAATGGCCCAGATTTGA +CACTGGTCAGGAAGCAGGTGGCATTGAACCTTCTCAGAGGCTCTGAAGGGAGGGGGAACA +GTAGAAGTTTTGCACCTAGGTTCTTCTTGGCACCACTTCTAAACCAGAGCAGCCTGGGCA +ACATAGTAAGACCTCCATCTCTACAAAATAAAAATAAAAAAACTCTGTATTTTTTTGTAG +AGATGGGGGTTTCGTCATGTTGCTTAAGCTGGTCTCAAAACTCCTGGACTCAAGTGATCC +TCCTGCCTCAGCCACCATGCCTGGCCATACATTCATCTTATTAATAATATACTCTGTGTC +TCTTACATGGGTATATATTAATAAATTCTAAGAAGTATATTTCTTGGTCAAAAGGTATGA +GTATTCTAAATTTTATTAGACATGGGAAACTTGCCTTCCAACATATCTCATTTTTTAATT +CTTAAAGTTGAATTGGCAAATATTGACTCTAGCCATCCTAATCTGTTATCCTTTTAGGCT +CCTATGGGTCCATTTTAGATATTTTTGGTTGTGTTGATTTTATTTCTTTTTGCTCCATTA +TATTGCTTCATTTCCCCTTTGTTTTTCCTTTATCCCTCTTTGATGACTCATCTTCATGCT +ATTCGGCCAGAATCTGGGTCTGGAGGAGTGTGAACCATGGAGGGTTTACATTATAAACAA +GACATCGCCTCTCAGCTGCTCATGCACCTGCTCCCTTGGCCTCCTGTGAAAACAGATGTC +CCAGAGCAGTTACAAGGCTCTTTCAGGAGAATTTCCTCCAAGAAGATTTTGCAACTCAAA +TGTGAAGCCTCTTCAGGACCATAAGTTCCATGGTAAGGACAGCATACTTCATCTGCTTGA +AAACTATTGGTTATTGACATGTTATACTATCTAGTATTTATATTAAAATTTTGCTTTTCA +GAAAATCCAAGGACTCCAGTTGGATTTTAGGCAAAAATGTCAATATCAGGCCACAAGACA +GAGGGTGGAGATAGCATGGAGGAGGGTCTGTTCAGGGACTGTAATGGCCCGGATTTGACA +CTGGTCAGGAAGCAGGTGGCGTTGAACCTTCTCAGAGGCTCTGAAAGGAGGGGGAGCAGT +AGAAGTTAAGCACCCAAGTTCTTCTTGGCACCACTTCTAAACCAGTTATTTCTACCCCTT +TTGTGAATGATTCTCCTCCTTGACTTGCAGAATCACCGGATTCTCTTAGATGTTAGTACT +TCCAGCTCTCTTTTCTTACCTTGGAGGCCTGGAAGAAGCTGGCTGCAGTGAAGGTCATCC +CTTAAAGGATATTTGATGGGCCCATTGTTCTCATGCTGGGTGGTTCTTTCCATCTGACAG +ACTCTCCATCTAACTATTGAGAATGGTGTAGAAGGGCAGGTTTCTGGGAGGAGAGGCCCC +CTCTCATTTTCTAACCATTAGCCATGGTTCCACCCTGGAAAGTTCTTGAGATATAGGGAC +ATGGCTAAGACTGATCTGCAAAAATGTTTTACTCATCTCTTTTTTTAAAAAAAATATTAC +CTCCAAGGTAAGTAGAGTTTCCGAAAAAAAATTTTAAAACAAGTTTTAGAATCTATGCTT +TGCTGAAAATGTCCTTGTTTTTTTTATATTTGTCTCCCCACAAAGAATTTACTGGGTTCA +TTAAGCACAGCTTTCTAACTGATGTGCCCAAATGGGTTGCCCTAATCTCAATATTGAATC +CCTCAGCCCTCGGATAATCAAATGGAGCTGGGACCAGCCTGAGCTCCCAAGATGGCTATC +TCTGGCTATGAGCAGAATCTAAATTTGCTATTTAATATGTGCCAAGATGTTTAAAAGTTT +GTGAAGTTCCGCCTTTGAGAATCATCCTTCAGCACATTGTTTCTCCCTGATACATATGGA +AATATGCTGTAAAGTCCTTCTAACATGTCCCAACAATGTCCTGGAAGTAGCTTGTCTTCT +CAGTGCGGCTGGAACTCAGGTAAGTACCCCTGAACAGGGCTGTATCACAACAGCTGCCCC +AGCAGCTCATGACTCTGCAATCACTGTGCTATTGTTGGTGCTATTAATATTTAAGCAGGA +GGCTTGGTGTAGCTGCCTGCTGAAACCCAGGCAGACTCAAGCCATGTGGCTGATACTCCT +GTCCTACTGTCAATGTGGCTAATGCTATTTATGCCAACTCCTCTGCAGGCCACAGTAGTC +CTTCTCCATGTCACAGTCTGTTAAAGATTCTCCTCATTGAAAGGCCAGGCACGCTGGCTC +ACACCTGTAATCCCAGCACTTTAGGAGGCTGAGGTGGGTAGATGATTTGAAGTCAGGAGT +TCGAGACCAGCCTGGCCAACATGATGAAACCCCATCTCTACTAAACATACAAAAAAATTA +GCCGAGTGTGGTGGCGCATGCCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAAT +CACTGGAACCTGGGAGGCAGAGGCTGCACTGAACCGAGATCGCACCATTGCACTCCAGCC +TGGGCAACAGAGTGAAACTCTGTCTCAAAAACAAAAAAAAAGATTCTCATCGAACTGGCT +TTCAGATGCACTTGAAAAATCTTTTCCCTGCACTCAAGCTTGCCAGTCAACTGTATTTGT +TCCAAGAGGCCCCACTCTAAGACCCTGCACCAACAATCTGTTTTCCCCTCTATGTGGAAG +TTCAGAAGCCAGCCCACCAGCCCTGTGTCCTATCCTTTTGGTGAGTTATTCCTCCAGGAT +CTTATTGTACTTTCCAGCTCTTTGCTCAGCCCAGTCCAGACTTGTCTTCAAAACACTGCC +CCTTAGAAAGAAAGTGAGTGTGTGTGTGTATGTGTGTGTGTGTGTGTTTATAAGGAAGCA +AGGAAGCAGCAGGACTTTCTCAAATGTGTTTCTTCCATCACAGGCATTGTTATACCCTTT +GCTATCTCATGGATAACACAGTTTATTGGATTTTTTGAGGTTTGCATTTTCTTGGCCTGG +GCTTTTGACCTTGCTTTTGGGAATATGTTTAGGTTACACTGCATGTGCTCAAGTGGGAGC +ACCATTCCTTGAGGTTTGTACAGAATCTGAACAGCACTATTATTATGAGATTTGGGATCA +AAGAGGTGAACTCTTTGAGGAGATCCTAAGGGTTTCCAGCAAGTTATAGAAGAAAGTGTT +TTCTTCCTCCTTTCCTTTCTCCTCATTTATTTTTTAAACCAGCTATGTGTTGGCTGATAC +GAGTCTGAGTGATGTATGCTTATATTCTAAAACGATCAGAAGGGCAGGTGTTCTTTCATT +ACAAATACTTTCTCCAAATGGCAGTGGCCCAGAGAGATAACTGGCCCACTGGGTAATTAT +TACCAGAAAGAAGCATTAGATCTCAATTGTTCTTCCTTTCAATTTTCTCCATGTTTATTG +CTTTTGATAAGCAGTTGGGTGACTTTTTACTGGTGTATAAATAACCATTTCAAGGCCAGG +CGCAGTGAATCACGCCTGTAATCCCAGCACTTTAGGAGGCTGAGGCAGGCTGATCACTTG +AGTCCAGGAGTTTGAGATTAGCCTGGGCAATATGGCGAAACCCCATCTCTACAAAAAAAT +CAATAGGGCATAAATAAATAAATAACGATTTTACCTAACAGTCTTCCTCATTTATCTACC +TTGGAGTTTATTTTGCAGAAATTTTGTGTTGAAAGAAAATGGCAGGAAGTAGAGCTATTC +GATGCGGGTTATTTTATGAATGATTTACTAAAAACTGTTGTTGACAAGGAAGTTTCGATA +TAGCTGCTTTAAAAATTGTCCAGGGGCCAGGAGCAGTGGCTCATGCCTGTTATCCCAGCA +CTTTGGAAGGCCGAGGTGGGCAGATCACCTGAGGCCAGGAGTTCGAGAGCAGCCTGGCGA +ACACGAAACCCCGTCTCTATTAAAAATACAAAAATTAGCCGGGCATGGTGTCGGGCGCCT +GTAATCCCATCTACTGGGGAGGCTGAGTAAGGAGAATCGCTTGAACCTGGGAGGTGGAGG +TTGCAGTGAGCCAAGATCGCACCATTGCACTACAGCTTGAGTGACAAGAGCAAAACTCTG +CCTAAAAAAAAAAAAAAGGTCAGGCACAGTGGCTCACGCCTGTAATCCCAACACTTTGGG +AGGCTGAGGCGGGTGGATCACCTAAGGTTGGGAGTTCGAGACCAGCCTGACCAACATGGA +GAAACCCTGTCTCTACTAAAAATACAAAATTAGCTGGGTGTGGTGTCGCATGCCTGTAAT +CCCAGCTACTCAGGAGGCTGAGGCAGGAGAATCACTTGAACCTGGGAGATGGAGGTTGCA +GTGAGCCAAGATCGTGCCATTGCACTCCAGCCTGGGCAACAAGAGCGAAACTCTGTCTCA +AAAAAAAAAAAACTGTCTGGGCTAGGCCAGGGGTGGTGGCTCACACCTATAATCCCAGCA +CTCTGGCAGGCTGAGGCAGGTGGATCACTTGAGGTCAGGACTTCGAGACCAGCCTGGCCA +ACATGGTGAAACCCCATCTCTATTTAAAAAAAAAAAAAAAAGCCCTGTGTGGTGGTGTGT +GGCTGTAATCCCACTGTAATCCCAGCTACTCAGGAGACTGAGGCACGAGAATCGCTTGAG +CCCTGGAGGTGGAGGTTGTGGTGAGTTGAGATCATGCCACTGCACTCCAGCCTGGGCAAC +AGAGTGTGACTCTGTCTCAAAAAAAAAAAAAGAAGAAGAAGAGGAGGAGGAGGAGGAGGA +AGAAAAAATTGTCCAGGTTGCCTTCTATGTCACAGGCTATGAAAAAAAAAAAAATCCCAG +GCTAAAAATATGGAGTAGAACTTCATATGGGAGCTCTGGAGATTGGCCATCCATTCCTCT +CTCCAGTGGACGTGGGTCAGCCTTCTGGTAAGATCTGATTCCCTGTTCATTTCCTTAGCC +GTCACAAAAGTACATAACTCTGTCTTCAGACTAATCATCTCTTGGCAAACTAGAATCACT +GTGGAGCACATACTGGCCAGTTGCTATATAGCAGCTTTGTATTACCCAACACATAAGGGA +ATCCATATCCCTCCAGGGCTATTTGAAGAACATGTAACTGAAAAGCAGGTTAGTTACTTG +CCGCATATAGAGTTCAATTAACAAGAGTGAAGTCTGTTACAAAAAAAGTGAATTTATACC +CAAGCTAGCTTGGGGAAAGGGGCACAAAACGTCCTGCCTTTAAATGTGCCTCTTCACCTT +TAGAGTAGAGAGCGGGCATTTTTATAAGGGAGGGGAGGAAATGAGCAAGGGTGGGATGCC +CCTGCTTCCAGGCAGTTATCTACCGGGCAGTTGAGTTGGCGCCTTCCTGGCAGAAGCGAG +TTGTAAAAGTGGCCAAGTAGGCATGCTTTTCACATCCCCTCCTAGTGGGTGTGACTTCCG +AGGTGACCCCCTGGAGATGGGAGTTCCCTGGGGGCATGCTTTACTTTGCAAATTGATTGT +CAGCTCTCGAGGAGAGACCCCTCTTAGAGCTCACAGTTAGACGAACTTGCCCTGTAGGGA +ATGTCTGGTGAGGGGAGGGGAAAGGTTATATTTGCATTTCTAAAGGGCTACGTAGGTTAC +AGGGAACAGGGGGAAAAGGAAGAGGAGAGAAAATAATAAAATAATTAAATTATCTCGTAG +AAAAATGGGGATACTCGGTTACAGAAACACAGTCCATTCACTTTTTCTGAAAGTCTAAAA +TCTATCCCTAGACCAAACCAGACCAAAAGAAAGCTGGACCCCATCAAATTGATTGACACA +AGGCATACAACGATGTTACACAAAAGGAGGTCGCTAACGCAGATCTGAAAGGTCAGGGAA +GCTTTCCAGAGGAAGTGATGTCTAAGGCAGGACCTGAAACACAAGTAGGCATAATAGTAG +GCAAAGAAAGATGCAGTAAAAGAGAACCAAGACGTGAGAGAGCGAGCACGGATTGTTAGA +GGAACTGAGGACAGTTCAGTGTGGCTGGAGCACCATGTAAGGTAGAGAGTAGCAAGAGAT +CAAGCAGGCAGGCAGGCAGGCGCCAGATTATGCAGAAACAACGATGTTGAGTGTCTGAAC +GTTGTCCTGATGGCAATAGGAAGCCATTGGAAAGTTTTATATAAAGGGGATGACAGTCTG +AGATATGCCTTTTTGAAAAACTATTGTGGTTGCACTGCAGTGATGGAGGGAACAGTTGGA +AAAGACAAGACTGGAAGTTGGAAGACTGCTTGCAAAGCTCTCCTAGTCTAGGTGGGAGAC +ATCAGTAGATGGAGAGAAACTGTTCTATTGTCAGGAACACCATCTGGGTTGCCTTGGAAT +GCCTGCAGTCACAACCTCTCACTTGGTTTTCATGTTCCCTGTTTGCACCGGCATTTGTGT +ATTTATAAGGATCACTCAAAGTGGTTTAAAAAAAAAAATGCACAATAGCTAAAGACCACA +CAAGTTACAGGCATAATTTTGTTTCCTGGGAGATTTTTGGAAAATAGAAAAGACTCCAGT +TTCCCATTTTTAATTTTGTTAATCTGGGGCTTACATTATTCAAAAGCTACAACATGCTCA +AAGTTTCATATTATGACAAATTAGGAGCCAGCTTCCATTCCTCTCTCTCTTACCTCTCAC +CTCTGGGGAATAATCAAGTCCTGTAAACACTTCCTAGGAAGTGTCTCACAGTCTTCCCAC +TCCTCTCTATGCTCCTGCCACTATCACAGTTCAACTTGCATCATCTTTTCCTTCAAAAGA +CCCCTAATTGTGTCCCTTCCTTCAGGATTCTGCATTTCTAGCCATTTTCCACTCTACAGC +CAGAGCGACCCTTCTAAATGTAAAATGATTATGTTCCCCCATCATTCTTTAAATGTTGAA +AATGACCCTTCATCGTCCTTGCAATAAAAAGCAGGTCTCTTGGCTGGGCGTGGTGGATCA +CGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGTGGATCATGAGGTCAGGAGTTCG +AGACCAGCCTGACCAACATGGTGAAACCCCATATCTACTGAAAATACAAAAATTAGCCAG +GCATGGTGGCGGGCACCTCTAATCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATCACTT +GACCCTGGGAGGCGAGGTTGCAGTCAGCTGAGATGGCCCCACTGCACTCTAGCCTGGGTG +ACAGAGCAAGACTCTTGTCTCAAACAAAACAAAACAAAACAAAACAAAAGCAGGTCTCTG +CTTCTCCTTCTTCAGACTGAACTTTTACCGCTCTCGTCTTGCATTCTCTGCTAAAGCTTT +TCTGAACCCCGTTCTCCCTTGTTATAGCTATACCTCAACTCCACGATTCAAGAAAGCTAT +TCCCCCTACTTGGAATGTGGTGTGTGGTATATTCACCTCTTCTTTTGGTTATCTCTTATT +CCTTCTCCCAGCTCTCGGTGTTTGTTGTTGTTGTTGTTGCTGTTGTTGTTTTTTGAGACG +GAGTGGCAAAATTTCAGCTCACTGCAACCTCTGCCTCCCGGATTCAAGTGATTCTCCTGC +CTCTGCCTCCCAAGTAGCTGGGATTACAGGCGGGTGCCACCACGCCTGGCTAATTTTTGT +ATTGTTAGTAAAGACAGGGTTTCGCCATGTTGGCCAGGCTGGTCTCAAACTCTTGACCTC +AGGTGATCTGCCCACCTCAGCCTCCCCGAGTGTTGGGATTACATTTGTGAGCCACTACGC +CCAGCAGCTCTCAGTCTTGTCTCTTCAGTCACAGTTTTACAATTCCCAGACTTGGCTAAA +TCCCCTTGTGATGTTGTTATAAACATCGATAGTTCCCCTATCAGAATCTCCACCACATTG +TTAATTTTTTTAAGTGCATCTCCTTCCTGACTGACCATTCTTGTCTTGTTCCCTTCACAT +ATTTCCTGGTATAGAGAAGGTTAAAAAAAATGCTTTGAATTAAAAATAAATTATGAAACA +ATCTTGAAAAAGAAGAACCAAGTTGGAAGGCCCACACTTCAATTTTAAAACCTACTACAA +AGCAACAATAATCAAGACAGTGTGGTACTGACATATGGATGATATTGTGGTGAACCCCTA +TTAACCTCAGTTGGGAAGGCACCAGGTTCAAAAGGCCAAAGAGTCCCAGAGCCAGCAAAT +GAGACATGGGGTTTTATTAGGGGGATTACATACAGGGGAGAGAATCCAGTGGCAGTGGGC +TGGGCAAGAAAACCGCAACCACTTGCAAAAAGTACTTTGTAATTTATACAGCATTTGCAC +TTAATACCCTACCCTTAACAATCCACTTGGCAACATTCATTTAACCCATAACTCAGGGCC +TCAAGCCCTGTATGGCCCATGTTCCATGAGACTGGCTGGAGATGCAGATGTTACTCACAG +ACAAGGAACAAATCTCCAGGTTGGCTATTCCTGAATTCCCTAGCTCAGAACACACATTCA +GGTGCATCTGCTATAAAGGCTCATTGGAAGGTTATGCTTGTTATTGCTACCAGGTGCATT +TATCCTACGGCTGGATATAGTTCGATGGAATACAGTTGACACTCTGGAAATAAACCCATG +ATTCTGTGCTCAACTGATTTTTTAACAACAGTGCAAAGACTATACAATGGGGAAAGAATA +TTGTTTTTAATAAATGGGATTGGAACAACTAGATACCCAGACGCAAAAGAGTGAAGTTGT +ACTCCTATGTCACATGATATATAAAAATTAACTCAAAATGGATCAAAGACCTAAATGTAA +AAAATAAAATTGGCTGGGCACAGTGGCTCACACCTGTAATCACTCCCAGTACTTTGGAAG +ACTGAGGCAGGAGGATCTCTTGAGGCCAGGGGTTCAAGACCAGCCTGGTCAACAAAGCGA +GACCTTGTCTCTAATAAAAAATTTAAAAATAAGCCGGGCACAGTGGCTCACGCCTGTAAT +CCCAGCACTTTGGGAGGCCGAGGCATGCAGATCATGAGGTCAGGAGATCGAGACCATCCT +GGCTAACACGGTGAAACCCCATCTCCACTAAAAATACAAAAAATTATCCAGGCGTGGTGG +CGGGCACCTGTAGTCCCAGCTACTCTGGAGGCTGAGGCAGGAGAATGGCATGAACCTGGG +AGGTGAAGTTTGCAGTGAGCCAAGATTGCACCACTGCACTCCAGCCTGGGCAACAGAGTG +AGATTCCGTCTCAAAAATAAATAAATTAAAAAAAATAAAAAATATGCAGCCATAAAATAG +AACGAGATGGGCTGGGAGAGGTGGCTTACGCCTGTACTCCCAACACTTTGGGAGGCCGAG +GTGGGTGGATCACTTGAGGTCAGGAGTTCGAAATCAGCCTGGCCAGCATGGTGAAGCCCC +ATATCTACTAAAAATACAAAAAAAAAAAAAAAAAAATTAGCTGGGCATGGTGGCGCATGC +CTATAGTCCCACTTACCTGGGAGGCTGAGGCAGGAGAATGGCTTGAACCTGGGAGGCCGA +GGTTGCAGTGAGCCGAGATCACGCCATTGCCCTCCAGCCTGGGCGACAGAGCAAGACTCC +GTCTCAAAAAAAAAAAAAAAAAAAGAAGGAACGAGATCAGCCGGGCATGGTGGGTGGCGG +CTCACACTTGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGCAGATCACTTGAGGTCAGG +AGTTCAAGACCAGCCTGGTCAACATGGTGAAACCCTATCTCTACTAAAAATATAAAAATT +GGCCAGGTGCAGTGGCTCACGTCTGTAATTCCAACACTTTGGGAGGCTGAGGCAGGCGGA +TCACAAGATCAGGAGTTCAAGACCAGCCTGGCCAACATGGTGAAACCCTGTCTGTACTAA +AAATAAAAAATTAGCTGGGTGCGGTGGCACATGCCTGTAGTCCCAGCTACTCAGGAGGCT +GAGGCAGGAGAATCACTTGAACCCAGGAGGCAGAGGTTGCAGTGAGCCGAGATCACACCA +CTGCACTCCAGCCTGGGTGACAGAGTGAGACTCTATCTCAAAAAAAAAAAAAAAAAAAAA +AATTAGCCAAGCGTGGTGGCACATGCCTGTAGTTCCAGATACTCGGGAGGCTGAGGCAGG +AGAATCACTTGAACTGGGGAGGTGGAGGTTGCAGTGAGCCAAGATCGCACCGCTGCACTC +CAGCTTGGGCGACAGAGCGAGACTCCATCTCAAAAAGAAAAAGAAAAAAAATAAAAAGAA +AGAGATCATGTATTTTGCAAGAACATGGATGGAGCTGGAGGCTATTATCCTTGGCAAACT +AACACAGGTACTAAAAAGCAATTAACTCATCTTCTCACTTATAAGTGGGAGCTAAATGAT +GAGAACTCATAAACACAAAGAAGGAAACAACAGACACTGGGGTCTACCTGAGGGTGGAGG +GTGGGAGGAGGGAGAGGAGCAGAAAAATAACCATTGGGTCCTGGGCTTAATACCTGGGTG +ATGAAATAATCTGTACAACAAACCCCCATGACACGAATTCACCTATGTAACAAACCTTCA +CATGTATCCCCGAACCTAAAATAAAAGTTTAAAAAATAAATAAAAATAAAAAGTAAAAAA +ACTAAAACTATAAAACTCTTACAAGAAAACATATGGCTAAATCTTCACGACCTTGGATTT +GGCAATATTTTCTCAGATATGACACCAAAAACATAAGCAACAAAAGAAAAAAACAGATAA +ATAGGACTTCATCAAAATGAAAATATTTTGTTCTCAAAAAACACTATCAAGAAACTGAAG +ACTCAGAGAATGGGAGAATATTTTTGCAAATCATATATCTGATAAGGGACTTGCAGAACA +CTTTTTTTTTTTTTTTTTTTTTTTTGAGACAGAGTCTTGCTCTGTCACCCAGGCTGGAGT +GCAGTGGTGTGATCTCGACTCACTGCAAGCTCTGCCTCCAAGGTTCATGTGATTCTCACG +CCTCAGCCTCCCAAGTAGCTAGGATTACTGGCATGTGCCACCACACCCGGCTAATTTTTT +GTATTTTCAGTAAAGACAGGGTTTCGCCATGTTGGCCAGGCTGTTCTCAAACTCCTGACT +TCAAGTGATCTTCCCACCTAGGTCTCCCAAAGTTCTGGGATTACAGGCGTGAGCCACCAC +ACCCAGCAGAACTTTTTTTTTTTAAATTCATATAGCAATAATAAAAAGACAACACAGTTT +ACAAATGGGTTGGATAATTTACAAATGCAAAAGATCTTAATAGACATTTTTCCAAAGAAG +ATATCAAAATGGCCAATAAACACATTAAAAGATGCTTAATGTCATTACACATTAGGGAAT +ACAAATCAAAACCACAATGAAATATAATTACACACACACCAGGAAGGCTATAATCAAAAA +GATTAATAATAACAAGTGTTGGTGAGGATGTGGAGGAATCAGAACCCTCATATATTGCTG +GTGAGAATGTTAAGTGGTGACACTACTTTGGAAAATAATCTAATAGTTCCTCAAAAAGTT +TAACATAGGCCAGGCGTAGTAGCTCACACCTATAATCCCAGCACTTTGGGAGGCTGAGGT +GGGCGGATCAACTGAGGTCAGGAGTTCGAGACCAGCCTGGTCAAAATGGTGAAACCCTGT +CTCTACTAAAAATACAAAAATCAGACAGACATGGTGGCACATGCCTGTAATCCCAGCTAC +TTGGGAGGCTGAGGCAGGAGAATTGCTTGAACTTGGGAGGCGGAGGTTGCAGTGAGCTCA +GATCATGCCATTGCACTCCAACCTGGGCGACAGAGGGAGACTTAGTCTCAAAATAAATAA +ATAAAATAAAATAAAATAAAATAAAATAAAATAAAATAAAATAAAATAAAACTTTAACAT +AGAGTTACCATATGATCCAGAAATTCCACTCCTAGAGAAATGAAAACATGTGTCCACACA +AAAACTTGTACATGAATATTTATACCAGCAATATTCATAATAGCCAAAGGGTGGAAACAA +CCCAAATTGTTCATCAACTAATACATGGATAAACAACTTTGTGTATATTCATACAATGGA +ATATTGTTTGGACATTGTCTTAGTTTGCTTTGTGTTGCTAAACAGAATACCACAGATTCG +GTAATTTACAAAGAAAATAAATTCATTTCTTACAGTTCTGAAGACTGGGAAATCCAATAT +CAAGGGGCTCACATCTGGCAAGGGCCTTTGTGCTGTGTCATCCCCTGGTAAAAGGCAGAA +GGGCAAGACAGCATGAGAGAGCAAGAGACTGCACTTGCAGGCATAAGCCCTTTTGTAATT +ATCATTAATCAATTCATGAGGGTGGAGCCCTCATGACCCAAACACCTCCCATTAGGCCCC +ACCTCCCCACACTGTTGTATTGGAGATTAAGTTTCCAAAACATGCTTTTTGGGGAACACA +TTCAAACAGTAGCAGCCATAAAAAGAAATGAAGCACTTATACATGCTACAGTATGAATGA +GCCTTGAAAACATTCTGCTGAATGCTGAGAGGCTAGTCACAAAAGACCACATACATGATT +TCATTTACGTGAAATGTCCATAACAGGAAAATCTGTAGAGGAGGAAAGTAATAATTTAAC +GGCCGGGCACGTTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCGGA +TCACGAGGTCAGGAGATTGAGACCATCCTGGCCAACATGGTGAAACCCCGCCTCTACTAA +AAATATAAAAAATTAGCCGGGCATGATGGCGGGCGCCTGTAGTCCCAGCAAGTCGGGAGG +CTAAGGCAGGAGAATGGCGTGAACCCGGGAGGCGGAGCTTGCAGTGAGCCCAGATTGTGC +CACTGCACTCCAGCCTGGGTGACAGAGCAAGACTCCAGTCTCAAAAAAAAAAAAAAAAAA +ATTTACCTCTAATCACTGCATTAGCTTTATCTCACAAATTTTGATATGTTGTATTTTCAT +TTTCATTCAGCTTAAAATATTTTCCAATTTCCCTTATGATTTCTCCTTGGGTTCTTCTTT +TTTTTTTTTTTTTTTTGAGACAGAGTCTCGCTTTGTCACCCAGGCTGGAGTGCAGTGGTG +CAATCTGGGCTCACTGCAACCTCCACCTCCTAGGTTCAAGTGATTCTCATGCCTCAGCCT +CCTGAGCAGCTGGGATTACAGGTGCCCACCATGACACCCGGCTAATTTTTGTATTAGTAG +AGACAGGGTTTCACCATATTGGTCAGGCTGGTCTTGAACTCCTGACTTCAAGTGATCCAA +CTACCTCGGCCTCCCAAAGTGCTGGGATTATAGGCGTGAGCCACCGTGCCTGGCCTCTTT +TTGGGATATTTAAAAAGGTGTTGCTTAACTTCCAAGTATTTGGGGGTTTTCTGGATAATT +TTTTTGGTTTCTTTAAATACAATTATCTTTTGATCTGAAATCATACTATAATTTCAATTC +TTTTAATTTATTGATACTTGTTTTATGGCTGAAAATATATTCTATCCTGGTGAATATCTT +ATGTATACATGAAAAGAATATGTATTATGTTATTGTTGGGTGAAAAATTCTATAAATGCA +AACTGAGTGACTGACAGAGGTTTTGTTTTTGTTTCTTTCTTTCTTTGTTTTTGACAGGAG +TCTCACCCTGTCACCCAAGCTGGAGTGCAATGGAGTGATCTTGGCTCACTGCAACCTCCA +CCTCACAGGTTCAAGCGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGCAT +GCACCACCACGCCCGGCTAATTTTTTGTATCTTTAGTAGAGATGGGGTTTCACCATGTTG +GCCAGGCTGGTCTCGAACTCCTGACCTCATGATCCACCTGCCTCGGCCTCCCAAAGTGCT +GAGATTACAGGCATGAGCCACTGCGCCCAGCCTTGACAGAGTTTTCGAAGTCTTCTACAT +GCTTTCTGATTTTTCATCCACTTTCTTTTTTGTTTGTTTATTTTTGTTTTTGTTCTTTTT +TTTTTTTAATGGAGTTTCACTCTTGTCGCCCAGGCTGGAGTGCAGGTGGCGCGATCTCGG +CTCACTGCAACCTCCGCCTCCTGGGTTCAAGCGATTCTCCTGCCTCAGCTTCCCGAGGAG +CTGGGATTACAGGCGCACGCTGCCACACCCAGCTAATTTTTGTATTTTTAGTAGAGATGG +GATTTCACCATATTGGCCAGGCTTGTCTCGAATTCCTGACCTCATAATCTACCCGCCTCG +GCCTCCCAGAGTGCTGGGATTACAGGCGTGAGCCACCGCGCCCAGCCTGTTTTCGTTCTT +TTTTGAGACACGATTCCACTCTGTTGTCCAGCTGGAGTGCAGTGGCACAATCAGGACTCA +CTGCAGCCTCAACCTTCCAGGCTCAGGCATTCCTCCCACCTCAGCCTCCTGGGTAGCTGG +GACGATGGGCATGCACCACCACGCCTGGCTAATTTTTTTGTATTTTTAGTAGAGACAGGT +TTCTTCATGTTGCCCAGGCTGGTCTCAAAATCTTGGGCTCAAGCGATCCACCTGCCTCAG +CCTCACATAGTGCTGAGATTACAAGCGTGAGACCCCACTCCTGGCCCACTTTCTATTGAT +TACTGAAAATTGAGTATTGAAATTTCTAACTCTAAATGTGGCTTTTTCTATTTCTCCTTT +AAGTTCTAACAGTTTTGCTCTATGTTTTTCAAAGTTTTGTTATTGGGTACATACACATTT +AAGATTTTAAAATCTTCTTGGGGAATTGAATTTTATCGTTATGAAATCTTCCTTTTATTT +CTGTAATATTTCTTGTTTGAAAGCTTATTTCAGGCCTGGCGTGGTGGCTCACGCCTGTAA +TCCTAGCACTTTGGGAGGCCACAGTGGGCAGATCACCTGAGGTCAGGAGTTTGAGACCAG +CCTGGCCAACATGGTGAAACCCTGTCTCTACTGAAAATACAAAAATTAGCTGGGCGTGGT +GGTATGCATCTGTAATCCCAGCTGCTGAGGTGGCTGAGGCACAAGAATCACTTGAACCCT +GGAGGTGGGGGTTGTAGTAAGCTGAAATCATACCACTGCACTCCAGCCTGGGTGACAGAA +CGAGACTCTGTCTCAAAGAATAAATAAATAAATTAGCGATTTAAAAAATTAAGAAAATTT +TTAAAAAGAAAGCTTATTTCCACTAGTGCCGTGACTCACGCCTGTAATCCTAGCACTTTG +GGAGGCCAACGTGGACAGATTGCTTGAGCTCAGGAGTTCAAGACCAGCCTGGACAATATG +ACAAAACCCCATCTCTACAAAACAATACAAAATATTAGCTGGGCATGGTGGTACATGCCT +GTAGTCCCAGCTACTCAGGAGGCTGAGGTGGGAGGATCACTTGAGCCCAGCAGATCGAGG +CTGCAGTGAGCTGAGCTCATGCCACTGCACTCCAGCCTGGGTGACAAAGTAAGACCCTCT +CTCTTAAAAAATTTTTTTTAAAATAAAGCTCCTTTTGTCTAATATTAATAGAGCCACTTC +TAGATTTATTTTGGTTAGTGCTAGCTTAATATATATTAATATATAATTTCTCCCTTTTAG +TTTGTGTTTTTAGAACATTACATTTAATGTAGTTATAAAGTGTTCATGCTAAATATACCA +TTTTTTTTTTTTTTTTTTTGAGATGGAGCTTTGCTCTCGTTGCCCAGGCTGGAGTGCAAT +GGCACGATTTTGGCTCACCACAATCTCCACCTCCCGGGTTCAAGCGATTCTCCTCCCTCA +GCTCCCATGCAGCTGGGATTGCAGGCATGTGCCACCATGTCCGGCTAATTTTGTATTTTT +TTAGTAGAGACAGGATTTCTCCATGTTGGTCAGGCTGGTCTCGAACTCCCGACCTCAGGT +GATCTGCCTGCCTCGGTCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACTGCACCTGG +CCTAAATCTACCATTTACTGTTTGTCTTCTTCTTTTTTTTTTTTTTTTTTTTTTTTGAGA +TGGAGTCTCACTGTGTCATCAGGCTGGAGTTCAGTGGTCTGATCTCGACTCACAGCAACC +TCCGCCTCCCGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCAGAGTAGCTGGGATTACAG +GCATCTACCACCATGCCTGGATAATTTTTGTATTTTCAGTAGAGATGGGGTTTCACCATG +TTGGCCAAGCTGGTCTCAAACTCCCGAGCTCAGGTGATCTGCCCGCCTCAGCCTCCCAAA +ATGCTGGGATTATAATAGATGTGAGCCATGGCACCCAGCTACTCTTTCTATCTATTCCTT +TTTTGTCACTTCTTTTGGGTAGACAAATTTTTTTTTTTTTTTCTGTGACAGAGTCTCACT +CTGCCACCCTGGCTAGAGTGCAGTGGCCTGATCTCGGTTCACTGCAGCCTCCACCTCTCA +GGTTCAAGCGATTCTTGTGCCTTGGCCTTCTAAGTAGCTGGGATTACAGGCATGCACCAC +CATGCCCAGTTAATTTTTTGTGTTTTTTCTAGAGATGGCGTTTTGCCATGTTGGCCAGGC +TGGTCTTGAACTCCTGGCTTCAAGTGATCTCCCTGCCTCAGCCTCCCAAAGTGCTGGGAT +TACAGGCGTGAGCCACCACATCCAGCTGAAAATTTTTGTAATTCCATCTTATTTGTACTA +TTGACTCATTAGCTGTATCTCTAAATTTTACTTCTTAGTAGTTGCTCTAGGTTTATAATA +TGCACTATTAATTTGTTAACAGTCTATCTTCAGATAATATTACACCACTTCACCTGTAGT +ATAAGAATTGTGGCTGGGTGCGGTGGCTCACGCCTGTAATCCCAACTCCTTGGGAGGCCA +AGGCGGGTGGATCACCTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAATATGGGGAAACG +ACAACAACAAAAAAATTAGCCAGGCATGGTGGCAGGTGCCTGTAATCCCAGCTACTTGGG +AGGCTGAGGCAGGAGAATCGCTTGAACCCAGGAGGTGGAGGTTGCAGTGAGCCGAGATTG +TGCCATTACACTCCAGCCTGGGCGACAAGAGTGAAACTCCACCTCAAAGAAAAGAAAAGA +AAAGAATCGTAATGCCAGGAGCAGTGGCTCATGACTGTAATCCCAGCACTTTAGGAGGCC +CAGGTGGGCAGATCACCTGAGGTCATGAGTTTGAGACCAGCCTGGCCAACATGGTGAAAC +CCCATCTCCACTAAAAATAAAAAAATTAGGCCAGTTACAGTGGCTCACACCTGTAATCCC +AACACTTTGGGAGGCCAAGGTGGGTGAATCACCTGAGGTCAGGAGTTCAAGACCAGCCTG +ACCAACATGGATAAACCGCATCTTTACTAAAAATACAAAATTAGCTGGGCGTGGTGGTGC +ATGCCTGTAATCCTAGCTACTCAGGAGGCTGAGGCAGGAGAATCCCTTGAATCCAGGAGG +CGGAGGTTGCGTTGAACCAAGATTGTGCCATTGCACTTCAGCCTGGGCAACAAGAGCAAA +ACCCCATCCAAAAAAAAAAAAAAAAAATTAGCCAGGCATGGTGGTGCACACCTGTAATCC +CAGCTACTTGGGAGGCTGAGGGAGGAGAATACGTTGAACCCTGGAGGCGGAGGTTGCAGT +GAGCCAAGATCATGCCATTGCACTCCAGCCTGAGCAACACAGTCAAACTCCAACTTAAAA +AAAAAACAAACAAAAAAAGAATTGTACATGAGTATCCTCCCACGTCCTTGTTCCTATCAT +TTTTTACCGTGATTGTTATACATTTCATTTCTCCACACTTTATGAGCTTCACAATACCTT +GTCACTAATTTATATTTTAAAATTATCTTTTAAAGAATACTAAAAATGAGAAAAAAATTT +ATATTCAGCAAAATATTTTCTTTTTCCAATATTTACTTTATTCCTTTGTGTCAATTCTCA +TTTCACCTTGGTATCATTTTCCTTTTCACCTGAAAACTTCTTTATAACATTTTTTATAGA +GTTAGTCTAATATTAATATCAATAAAGTATATCAGATTATTTTGAATCTAAAAATATTTT +TATCCCACCTTCATTTTTTTTTTAAAGAGATGAGGTCTCATTATGTTGCCCAGGCTGGCC +TCAAGTGATCTTCCTGCCTTGGCTTCCAAAGTGCTGTGATTACAGATGTAAGCCACTGAA +CCCAGCTCCAGCTTCATCAAGAAGTCTTCTGTCGGGCTGGACATGGTGGCTCATGCCCGT +AATCCCAGCACTTTGGGAGGTCGAGGTGGTGGATCACCTGAGGTCAGAGTTCAAGACCAG +CCTGGCTATCATAGTGAAACCCCATCTCTACTAAAAATACAAAAATTAGCTGGGCATGGT +GGCTCATGCCTGTAATCCCAGTTATTCAGAAGGCTGAGGCAGGAGAATCACTTGAACCCG +GAAGACAGGGGTTGCAGTGAGCCAACATAGCACCACTGCACTCCAGCCTGGGCGACAGAG +CAAGACTGTCAAAAAAAAAAGGAGAAGTTTTCTGTCATTCATTCTTACCTTTGTTCTTCC +ATACATAATCTTGCTCCACCCTTCCCTCAATTCTGGTTGCTTTAGGACTTTGTCTTTATC +ACTGGTTTTCAGAAATCTGATGAACATGCACATCAGTGCCATTTTCTTTATATTTCTTCT +GCTTGGAGTTTTTTGAGGTTTTTTAATCTGTTGGTTTATGGTTTCATTAAATTTAGGAAA +TTTCAGGAATTGTTTTTCAAATAATGTTTTTTCCCTTTTCTCCTTATTTTTCTGGAACTC +CAACTCCATGTATGTTAGGCAGTTTGATATTGTCTCATAGATCCCTGATAAACAAATAAA +TAAGTTTGATTTTTGGGTTTTTTTTTTTTTCCAGTCTCTTTTTTTGCCATGTTTCTTTCT +TTTTTTTTCTTTTTTTGAGAAGGAGTCTTGCTCTGTCGCCCAGGCTGGAGTGCAGTGGTG +CAATCTCAGCTCACTGTAACCTCCACTTCCTGGGTTCAAATGATTCTCCTGCCTCACCTT +CCTTAGTAGCCAGGATTACAGGTGCCCATCACCACGCCTGGCTAATTTTTGTATTTGTAG +TAGAGATGGGGTTTCACCATGTTGGCCAGTCTGGTCTTGAACTCCTGGCCTCAAGTGATC +CACCACCTCGGCTTCCCAAAGTGCTGAGATTACAGGCGTGAGCCACTGCGCCTGGCTGCC +ATGTTTCATTTTGGATGGTTTCTGTTGTTATGCATTCAGTTCACGCAAAATTCTTTTTCT +CTGCAGTGTCTACTCATTTCATCCAGTATATTTTTACTATTACATAGTGTATTTTCATGT +CTACAAATTCTATTTTAAAATATCTTCAATTTCTGTCATCATTTTGTTAACGTTTTTCTT +TACGTTCTTGAACATGTAAATAATAGCTGTTTTAAAGGTAATTCCATCTTAATTACCATT +TCTGGGTCTCTTTCCATTGATTTATCTACAGGTTATGTGTTATATATTCTGCTTTCCATG +AATAATAATGTTTCATTGGTTCCTAGATATTCTCAATTTGCATTGTTATATGCTGGGTTT +TGTTATACTCCTTTATAAAAATGAACTTTGTTTTAGCATTCAATTAAATTGCTTGTGAAT +TAATTGACATCAGTGGGACTTCTGGGATATTAGATATTGTCTTCTCCTTTTTTAAATCTG +GGTGCTGGTTATGTGGGTATGCTTATTTTGTAAAATTTATCAAACTTATTTATGATTTGT +GTATTTTTCTGTTTATATGGTACATTAACATATATTCAATTTTAATACCTTTATTTTAGA +AATGTAAACGGGGCTGGGCACAGTGGCTGACACCTCTAATCTCAGCACTTTGGGAGGCCA +AATTGGGAGGATTGCTTAAGGCCAGGAGTTCAAAACCAGCCTGAGGCCAGGCACAGTGGC +TTACGCCTGTAATTCCAGCGCTTTGGGAGGCTGAGGCAAGTGAATCACTTGAGGTCAGGA +GTTCGAGACCAGCCTAGCCAATGTGGTGAAACCGTCTCTACTAAAAATACAAAACTTAGC +CAGGTGTGGTGGCGGGGGCCTGTAGTCCCAGCTACTTGGGAGGCTGAGGTAGGAGAATTG +CTTGAACCTGGGAAGCAGAGGTTGTGGTGAGTAAGATTATGCCACTGCACTCCAGCCTGG +ATGACAGAGTAAACTCTGTCTCAACAACAACAACAACAACAACAACAACAACAAACAGCC +TGGGCAATATAGTGAGACCCCATCTCTACCAAAAAAAAAAAAAAGTAATTGGGATAGAGC +ATTCCCCTTTTTTTCTCTCCACTTTGATTCTCCCCAGAAGATGATGGGAGGCTCAAAGCA +TATCAATGCACTCGAAGGAGTGATTCTGGGTAAGTGAGTATGCACATTCTCCCCTACGTA +AATCATCCCATGATCTAGACTTGGAGTAGACCAGATTATGGCCTAATATTCAAGCTAATA +TCTTCAATTCAGTTTTGCAAATCACAGGATGGATGATTTGTCCCTGTCTGACAGGCTTTG +ATGTCTTCTCCTTTATTGATTTGAAACTTAGGAGGTAGAAAGAAGAGTATTTTCTTTTCT +TTCCTTTTCTTTTGAGACAGAGTTTCGCTCTTGTTGCCCAGACTGGAGTGCAATGGCACA +ATCTTGGCTCACCACAACCTCTGCCTCCTGGGTTCAAGTGATTCTCCTGCCTCAGCCTCC +CGAGTAGCTGGGATTACAGGCACGTGCCACCACGCCCGGCTAGTTTTGTATTTTTAGTAG +AGACGGGGTTTCTCCATGTTGGTCAGGCTGGTTTTGAACTCCCGGCCTCAGGTGATCCAC +CCGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGTGTAATCCCACCACCCCTGGCGAAAG +AAGAGTATTTTCAACAAGACCTCAAATGAAAACAGACATTCTAGTAATAAATGGGACTTG +ACATCTTTGACCCCTCCATGTGACTAAAATTTAAGTTTCATTTTAAAACATGAAGATAAT +GATATGTCTGTTTCTGAACCACTGGATTGAAAATTTACACATGGATGAGTTCCATAATTT +CACATGTTTAATTGGTCATTAAGGCTACCTTAGCAACTGCTACATCAAATGATAGCTTTT +GACTGGGCATGGTGGCTCACACCTCCCAAAGTAGTCCCAGCATTTTGGGAGGCCGAGGCA +GGTGGATCACTTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACATGGGAAAACCCCGTC +TCTACTAAGAATACAAAAATTAGCCAGGCATGGTGGTGCGTACCTGTAATCCCGGCTACT +TGGGAGGATGAGGCAGGAGAATCGCTTGAACCCGGGAAGTGGAGGTTGCACTGAGCCGAG +ATCATGCCACTGCACTCCAGCCCAGGCAACAGAGCAAGACTCCGTGGCTGAAAAAAAAAA +AAAAAAGTAGCTTTTACAATTCTGACCTATAGAGAGCTTTCTTAAAGCAACTCAAAGGCC +AGGTGCAGTGGCTTACGCCTGTAATCCCAACATTTTGGGAGGCCTAGGCTGGTGGATCAC +CTGAGATCAGGAGTTTTAGACCAGCCTGACCAATATGGTGAAACCCCGTCTCTACTACAA +ATAGAAAAATTAGCTGGGCATGGTGGTACACGCCTGTAGTCCCAGCTACTCAGGAGGCTG +AGACAGGAGAATTGCTTGAACCCAGGAGGCGGAGGTTGCAGTGACCCGAGATCGTGCCAC +TGCGCTCCAGCAGCCTGGGTGACAGAGCAAGACTCTGTCTCAAAAAAAAAAAAAAGCAAT +TCAATAGCATTAAGTAAAAAGTGATACCTTTATGAGCTACTAAAATGTGTATATGGCCAG +GCATGGTGGTGCAGGCCCATAATCCCAGCACTTTGGGAGGCTGAGACAGGCAGATCACTT +GAGCCCAGGAGTTCAAGATTAGCCTGGGCAACATGGAAAGACCCTATCTCTACAAAAAAT +TTTAAAAATAGTAAAAGACAATCTGTATATATCAAATAAAAATTCCCAGCCAAGTATGAA +ATTCTCTAAAGCTTTATACATGAAATGTATAACATGTAATTATCCTTTATTATAGCTAGA +GTGGGTTTCTCTTATGAATTGTGGTACAATGTCCAAATTTTTGATCTGATCATTTCTGAA +CAACAGAAGGAAGACATCAGTGACAGCAACAACATATACAATTTAAACTTTCATATGTAT +GGTCTGAATAAGAAAATTACATTTCAATAACAAAAAAGGTGTTTTTTTCAATCACACTGC +TAAGTTTTTGAGATATCAAATTGAGTAAAACATGGCCTAACATCTTAAGAAGTTTACAGT +CAGGTAAGAACAATTCATTTTTTCATTCAGCAATATCATAGCACATCTGTATTGTGCCAG +GGAATTTTCTAAGAGCTGGGGGTGGAGAGGGGTGCACAGTGAGCAAAATCGACAAAGATC +CCCATCCTTATGGGAATTTACATTCTCATGGAAAAAATAAACAATAACCAAATAAATATA +TATATTGGATGGTAAAAAATGCAACTGAGCAAAAGTAGAAGGAGGATAAAGTGTGTGTGT +GTTTATGTGTGTGTGTTGTGTTGGGGAGGACACGGTTGTCATTTCTTTTCTTGGATAGTG +GAAAACCTCAATATATTTAGACTTAGTGAGCTGCAATCCACTTATATGATCCCAGTTTTG +TTGGCACCACCTAAAGCATCATGGTAGGTCTAGTCTAAAGTATGCCTTCTTCTCTCCCAA +GCAAGTTGACCTTGGCCATGTCAGGGTCCCAGAGCTTCTTCACATCTTGCCGGATCTGTC +CTGACAACCGCAGTAAACACCAAGTGCTGGTGCCTTCTACCTTCTTTATGACCCACTGGG +AAATCAGGGGCAAACTGATAGTGGCACAATGGTTGTTCTTCTTTCTGGAGAACGCTTTTT +TAGATTTTGCTTTGTATAACTTACCCATAAACAGTACTTTCACTTTAAGGATTTCAGCTG +TATTTAAATACAAACAGGGAGCTGGCTGCAGTGGCCCAAACCTGTAATCCCAACACTTTG +GGAGGCCAAGGCAGGAGGATTGCTTGAGGCCAGGAGTTCCAGACCAGGCTGGGCAACATA +GAGAGACTCTGTCCTTACAAAATCTTTAAAAATAGCTGGGGTGGGCCAGGCACGGTGGCT +CACGCCTGTAATCCCAGCACTTTGGGAGGCCAAAGCGGGCAGATCACGAGGTCAGGAGAT +CGAGACCATCCTAGCTAACACAGTGAAACCCCATCTCTAATAAAAACACACAAAAAAGAT +TAGCTGGGTGAGGTGGCACGCGCCTGTAGTCCCAGCTACTCAGGAGGCCGCGGCAGGAGA +ATAGCTTGAGCCCGGGAGGCAGAGGTTGCTGTGAGCCAAGATCTCACCCCTGCACTACAG +CCTGGCGACAGAGCGAGACTCCATCTCAAAAAATAAATAAATATATAAAAATAAAAGAAG +TGAAGTGATAGGAATAATATTGGGTTGGTGCAAAAGTGATTACGGTTTTTGCCTTAAAAG +CAGTGACATTAGGCCGGGTGCGGTGGCTCACGCCTGTAATCTCAGCACTTTGGGAGGCCG +AGACGGGCGGATCCCCTGAGGTCGGGAGTTTGAGACCAGCCTGAACAACATGGAGAAATC +CCATCTCTACTAAAAATATGAAATTAGCCGGGCGTGGTGGCACATGCCTGTAATCCCAGC +TACTCAGGAGGCTGAGGCAGGAGAATCACTTGAACCTGGGAGGCGGAGGTTGTGGTGAGC +CAAGATCACGCCATTTGCACTCCAGCCTGGACGACAAAAGCGAAACTCCGTCAAAAAAAA +AAAAGCAGTAAAAGCAATTACATCAACCTAATAGCAGGGCATGGAAGCTATTTTGCCTGA +GTAAAGATTCCCAGCTTTGTACTGGGCAAGTTACTGAACTTCTCTTTGCCTCAGTTTCCC +ACTTAAAAATTGAGATAATAATAGTGCCTCTGTTATGGGGATTAAATAAGATAATACATA +GGAGAGAGGAGTGGTTCTGAAACTTTAACTTGTATACAGATCTCTTTTAAATGCAGATTC +TGGGATGTCCCCAAGAATCTGCATTTCTAACAAGCTCCTGGGGCTGCTGACTCCACTGCT +CCACAGACCACACTTCTGTGTCAAGGTTGTAAGGCACGTAGAACACTGCCTGGCACACAG +AGTGCGCTGAATAAATTTAACTATGGTTATATTTTCACACAGTTGAGTTGGCAGGGAAAC +CAGATTAAAAAGCCAAAAAGTTTCTCTCCTTCTCTATCAGATGTTTCCTGACGATACTGT +ATCCTTGAATAGAATTCTACTGCATTCTGAGTTCAAGTATGAATGTGCATATGGATAACA +GGTTTTCATTTTTAAAAGCTCTCAATAGCAGCTTGAAGCACTATTCTTGAATTTATGGTT +TTAAGCCGTATCAAAGTACCTAATACCATGTGCATTGCAGGCATTTATTTAATACTTGGA +TCAAAGAATGTCCAGACTATCTGAATAAATCATCCCTGTAGGAATGAACAGTGCTGCTGG +AGTTCGGTTTTATTTAATGTGGTGGCATGTATGCTAAACTACGACTTCAAGAATGTGGCA +ATTGTGTTCTAAAATCCAAAGTATGTTACACTAATCTAATTGCTAGAATCTCATGCAAGG +CTGACTCTAACCCAACTACTTCCTTCTTCCTGTGCGGCTCAACCCAGACTTTACATGCTA +ACAGTGCCCTCTACTGTTCAGCAACCAGTCGGTGCTACTAAATCCAATTCATAAAGCTGC +AAAATCAGAATTCAGACAACTGGGTTCACTTACCACACAAACGTAGCTTGCATCTGCCTT +TATAGGAGAGAGGGCGGCTGTCAAGGAGCGGTCCATACTGGGAGGGGCTGAGACTGATTT +CTGGGCCACCAATGTGAAGCTGACCAGGATCCCCAGAGAGGAGAGAAAAGCTCGTTGTTG +TTTTCCTCTGAAGCACT diff --git a/test/csq/ENST00000520795/ENST00000520795.fa.fai b/test/csq/ENST00000520795/ENST00000520795.fa.fai new file mode 100644 index 0000000..78ba555 --- /dev/null +++ b/test/csq/ENST00000520795/ENST00000520795.fa.fai @@ -0,0 +1 @@ +8 272897 23 60 61 diff --git a/test/csq/ENST00000520795/ENST00000520795.gff b/test/csq/ENST00000520795/ENST00000520795.gff new file mode 100644 index 0000000..25b95b4 --- /dev/null +++ b/test/csq/ENST00000520795/ENST00000520795.gff @@ -0,0 +1,8 @@ +8 ensembl_havana gene 1 272897 . - . ID=gene:ENSG00000076554;Name=TPD52;biotype=protein_coding;description=tumor protein D52 [Source:HGNC Symbol%3BAcc:12005];gene_id=ENSG00000076554;logic_name=ensembl_havana_gene;version=11 +8 ensembl_havana transcript 94944 213048 . - . ID=transcript:ENST00000520795;Parent=gene:ENSG00000076554;Name=TPD52-012;biotype=protein_coding;havana_transcript=OTTHUMT00000379392;havana_version=1;transcript_id=ENST00000520795;version=1 +8 havana exon 94944 95095 . - . Parent=transcript:ENST00000520795;Name=ENSE00002095249;constitutive=0;ensembl_end_phase=-1;ensembl_phase=0;exon_id=ENSE00002095249;rank=3;version=1 +8 havana CDS 94944 95095 . - 0 ID=CDS:ENSP00000430865;Parent=transcript:ENST00000520795;protein_id=ENSP00000430865 +8 havana exon 106143 106258 . - . Parent=transcript:ENST00000520795;Name=ENSE00003683821;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00003683821;rank=2;version=1 +8 havana CDS 106143 106258 . - 2 ID=CDS:ENSP00000430865;Parent=transcript:ENST00000520795;protein_id=ENSP00000430865 +8 havana exon 212872 213048 . - . Parent=transcript:ENST00000520795;Name=ENSE00002102583;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00002102583;rank=1;version=1 +8 havana CDS 212872 213048 . - 2 ID=CDS:ENSP00000430865;Parent=transcript:ENST00000520795;protein_id=ENSP00000430865 diff --git a/test/csq/ENST00000520795/ascii-art.txt b/test/csq/ENST00000520795/ascii-art.txt new file mode 100644 index 0000000..5ba4bd7 --- /dev/null +++ b/test/csq/ENST00000520795/ascii-art.txt @@ -0,0 +1,9 @@ + +tscript 213048 +exon 212872 213048 +cds 212872 213048 + + 213028 213040 213048 + AAAGCCCGAGTCCAAGCCCga + A------------AAGCCC + diff --git a/test/csq/ENST00000520795/ascii-art.txt-l b/test/csq/ENST00000520795/ascii-art.txt-l new file mode 100644 index 0000000..5ba4bd7 --- /dev/null +++ b/test/csq/ENST00000520795/ascii-art.txt-l @@ -0,0 +1,9 @@ + +tscript 213048 +exon 212872 213048 +cds 212872 213048 + + 213028 213040 213048 + AAAGCCCGAGTCCAAGCCCga + A------------AAGCCC + diff --git a/test/csq/ENST00000520795/long-inside-del.txt b/test/csq/ENST00000520795/long-inside-del.txt new file mode 100644 index 0000000..fe6e56c --- /dev/null +++ b/test/csq/ENST00000520795/long-inside-del.txt @@ -0,0 +1,3 @@ +213028 AAAGCCCGAGTCC A inframe_deletion|TPD52|ENST00000520795|protein_coding|-|3GLGLW>3W|213028AAAGCCCGAGTCC>A +213028 AAAGCCCGAGTCC A inframe_deletion|TPD52|ENST00000520795|protein_coding|-|3GLGLW>3W|213028AAAGCCCGAGTCC>A + diff --git a/test/csq/ENST00000520795/long-inside-del.txt-l b/test/csq/ENST00000520795/long-inside-del.txt-l new file mode 100644 index 0000000..fe6e56c --- /dev/null +++ b/test/csq/ENST00000520795/long-inside-del.txt-l @@ -0,0 +1,3 @@ +213028 AAAGCCCGAGTCC A inframe_deletion|TPD52|ENST00000520795|protein_coding|-|3GLGLW>3W|213028AAAGCCCGAGTCC>A +213028 AAAGCCCGAGTCC A inframe_deletion|TPD52|ENST00000520795|protein_coding|-|3GLGLW>3W|213028AAAGCCCGAGTCC>A + diff --git a/test/csq/ENST00000520795/long-inside-del.vcf b/test/csq/ENST00000520795/long-inside-del.vcf new file mode 100644 index 0000000..6c0da30 --- /dev/null +++ b/test/csq/ENST00000520795/long-inside-del.vcf @@ -0,0 +1,6 @@ +##fileformat=VCFv4.2 +##contig= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO +8 213028 . AAAGCCCGAGTCC A . . EXP=inframe_deletion|TPD52|ENST00000520795|protein_coding|-|3GLGLW>3W|213028AAAGCCCGAGTCC>A;type=ENST00000520795:81083598-AAAGCCCGAGTCC-A diff --git a/test/csq/ENST00000520868/ENST00000520868.fa b/test/csq/ENST00000520868/ENST00000520868.fa new file mode 100644 index 0000000..c3581f7 --- /dev/null +++ b/test/csq/ENST00000520868/ENST00000520868.fa @@ -0,0 +1,621 @@ +>8 8:101697944-101735137 +TAAACTCATACAGATATAAATAAATCAGTGAACAAATGGAATGTTTGATGGGCAAGCAAA +CATTTACATAGTTTCAAAATACCTCCCTACAACATAGTAATTATAAAGAGAAAAATAGCA +ACTTTATAGTGGCAGATAACAACTTAATCAAATGCTCAAAACAAACGCCATTGGTAATGA +GATAAAACAGAATCACAGGCCACCAGACAGGATGTAATGAGAAGAATGCAATGTCAATTC +TGTGATAGTTCCACCAAAATGTATCATTTCAATCTAATAATAAAGAGGTATCGGACAAAC +CCAGATTGAAAGATATTCTATTGAATAACTGGTCTATAATGTTCAAAAGTGTCAAGGTCA +TGAAAATCAAGGATAGACTGAAGAACTGCTCCAAAGTGAATGAGCAATTCTTACGTTTTA +GGCATGACAATGAAATGTAACTCCCGATTTTGAACTAGATCCTTTTGCTACGGAGGACAT +TATTGAAGCAATCAAGGAACTTGAGTGGGGCGTGAGGATTCGACGGTGCTGATCGTTTTC +ATGGCGGTGTCATGGTTATGGAGGAGAATGTCCTTGTTTCTAGGAAATAAATATGTGTTT +GGGTACGATGCATTAGGTTAGCAACTCTCAAATGGTTTAGAAAATAATTTTTTGTACTGC +GTTTCCACTTTTTCTATAGCCTTTGTCATTGCTTCAAATTAAAAAATTAAATTCCATTTA +TAAAAAAAAAAGCTTAGCACAAAAGCAAGACATTTTGATTTTGCTACTCTGCTGTAGGGG +GTTTGGAGGCTTGGATGTGGATATGATTGTTTTGATTTGTTTAAAAATGTAAAACCATTC +TTTAGCTGCAATGGACTTAAGTTTCACTTCAGACCTAACTCCCCATCTCACCCTCCACCC +CCCTCAATTATGAAGGACTTTTACTTTCTGCTGAATTCTGAGTTAGTTTTTAAGAGGAGC +TATTATTTTTAAAATAAGAGCAAGAACAAAACAATGAAGACACCTTTAAAAAATATGCTG +TAACTGGGTTAGCCTCTAAGGTGGTGCTGCTTGGTGCCTCCTCATACCTCACCTCCAAAC +AATTAAAAATATTATTTTAAATGGTTAAAATTTAAAATATTAATAAACATATAATATATT +ATAGTATAATTAAGTATAATATATAATTAAGTATAATCTATAAATATAGTATAATTAAGT +ATAATAAAATATACTTAAAATATTAAGTATAACACGACCAGGGGCAGTGGCTCATGCCTG +TAATCCCAGCATTTTGGGAGGCCGGGGTGGGTGGATCACTGGAGGCCAGGAGTTCAAGAC +CAGCCTGACCAATATAGTGAAACCCCCTCTCTACTAAAAATACAAAACTTAGCTAGGCGC +GGTAGCCTGTGCCTGTAATCCCAGCTACAGAGGAGGCTGAAGCAAGAGAATCGCTTGAAC +CTGGGAGGTGGAGGTTGCAGTGAGCCAAGATCGTGCCATTGCACTCCAGTCTAGGCAACA +GAGTGAGACTTCATCTCAAAAAAAAAATACACTGGACTTTACCCAGATTAAAACCTTATG +CTCATCAAAAGATGCCATGAAGAGAATGAATTGACAAGTTGTCTATTAGACATATAGAAT +GGGAGACTATATTCAAGATAGATGTATATGACAAAGGACTTGTATCCAGAACATATAAAG +AAATTCTACATCTCAGCAATGAGGAGACAAAAACCCAATTAAAAATAACTGGGCAAAAGT +CTTGAACAGACACTTCATAAGAGATATGAATGGCCAATATGCAAGAAAAAAAGTGCCCAG +AATCCCTAGTCATCAGTAACAGGAACCTTTAAATTAAAAGAGGCTTAAGAGATATGTTGA +CCAACACAAATAACTAGACTTATTTAAATCCTAATTCAGACAAATAACATGTAAAAAAAT +TATAAAACAACTGGAGATGTATGAACACCCACTGGATATTTTATATTAAGGTATTCTTGG +CCAGGCGCAGTGGCTCACGCCTGTAATCCCAGCACTTTGGAAGGCTGAGGCGGGCGGATC +ACTTGAGGTCAGGAGTTTGAGACCATCATGGCCAACATGGTGAAACAGTCTCTACTAAAA +ATACAAAAATTAGCTGGCCATGGCGGCACACGCCTGTAGTCTCAGCTAATCGGGAGGCGG +AGGCAGGAGAATCGCTTGAACTCAGGAGGTGGAGGTTGCAGTGAGCTGAGATCCTGCCAC +TGCACTCCAGCCTGGGCAACAGAGTGAGACTCTGTCTCAAGAAAGAAAAAAAGAGAGAGA +GAGAGAAAGGAATTCTTACTCATTTATTTTAACTGGGATAATAGTATTGTGGCAATAATT +TTAAAAGTCTTTATCTTTTATACACACTTTGAAATAGTTACAGATAAAATGACATGAGGT +TTGAAATTTGCTTCAGAATAATCTAGGGACATGTGAATTGGGGGAATGTAAATGAAAGAA +AATGAACCAAATGTTGAGAGTTGTTGAAAGCGGGTGATAGGAACATTGGCTTTATTACAT +TACTTTCTATACTTTTGTACACATTTGCAAGTTTCCAAAATAAAAACAGAAAAGGGCAAA +ACAACAAAAAAAATTGAGAGGAGAAGGGAGAGAGGAAAGAGAAGGGAAAGTAGAATAAGA +TCATTGAGTGTTAGATTGTTAGATAGTTGATACTATTAAAAAATTGACAGACCAGATAAT +AAAAGGTTTAGTTAAAAAAAAAAAAAAAAAACGGCCAGGCACGGTGGCTCACGCCTATAA +TCCCAGCACTTTCGGAGGATGAGGCAGGGGTATCACGAGGTCAGGAGTTCAAGACCAGCC +TGACCAACATGGTGAAACCCCATCTCTACTAAAAATACAAAAATTAGCCGGGTGTGGTGG +CACATGCCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATTGCTTGAACCCGGG +ATGCAGAGGTTGCAGTGAGCGGAGATTGTGCCATTGCACTCTAGTCTGGGTGACAGAGCA +AGACTCCGTCTTGGAAAAAAACAAACAAACAAAAAAAACAGGTGGGCTGGGTAGTTCATG +CTTGTAATCCCGGCACTTTGGGAGATTGAGGCAGGAGAGTCGCCTGAGCCCCAGAGTTCA +AGACCAGTCTGGGCAACATAGTGAGACCTCATCTCTTCAAAAAATAAAAAATACGTTAGT +CAAGCATGGTGATGAGTGGTTGTCTCAGCTACTTGGAAGGCTGAAGTGGGAGGATCACTT +GAGCCTGGGAATTTGAGACTGAAGTGAGTAGTAATCACACCACTGCACTCCAGCCCAGAC +AACAGAGTGAGACCCCATCTCAAAAAAAAAAAAAAAAAAGTAACATAATTAGAACAAAAA +TGCAATCTTTTCTAAATACCAAAAGATGTAGTACATAAAGAAAAACATAACATTACATAT +CTAGCAATAAGGTATTAAATGTGTCAAAGGACATGTTTAATACTAAAAGACACAATTAAT +AATGGATATGCATACATGAACATACATACACGTATATTTTACTTTATTCAAAATATATAC +ATCAGTACATATACTTACATGTACGTATCTCCTATATAAATTACACGTGTGTGTGTAGGT +ATATGGAGATATATATCTCCATCCTAAAGCTGGCATCTTACGTAACAGTGAAATACTAGA +GACTTTTCGACTAAGGTCAGAAACAAGACAAAGATTCCTACTGTCTCCACTCCTTTTTTT +TTTTTTTTTTTTGAGATGGAGTCTGGCTCTGTTGCCCAGGCTGAGTGCAGTGGCGGGATC +TCGGTTTACTGCAACCTCCACCTCCTGGGTTCAAGCAATCCTCCCACCTCAGCCTCCCAA +GTAGCTGAGATTACAGATGCCTGCCACCACTCCCAGCTAATTTTTGTATTTTTAGTAGAG +ACGGGGTTTCACCATGTTGGTCAGGCTGGTCTCAAACTCCTGACCTCAGGTGATCTGCTG +GTCTAGGCCTCTGTGGCCCAAAGTGCTGCGATTACAGGTGTGAGCCACCACACCCGGCCC +ACTAGTATTTACACAACAGGTATTTGACCAATACAATTAGACAAAGCAAAGGCATAAAAA +TTAGAAGAAAAGAAAAAGTGAAACTATCTCTATTTGTACATGACATGATAGCACACCTCA +GACCCTGGGAAAAAATGATAAAATAAACTCAATTTTAAAAAAATCAATGTAGCAGTATAT +AAAAATTAACATACAAAAATCAACACAAGTAATTTTTTTTTCATATACGCAAGTAATAAC +CAGTTGGGATATATAATGGTGGAAGAAAAAAACCCATTTACAAAAGTAACAAATAGCTAA +AATAGGAATGAAACTTAACAAGAAATGTTCAAAACCTATATGAATGAAACTATGAAACAC +TCCTGAAATACCTGAAAGTGAACTTGAGCAAAAAGAAAGACTTCTGTTCTTGCCTAGGAT +ATCTCAGCTTCATTAAGATTTCAATTCTAGACTGGGTGCAGTGGCTCATGCCTGTAATCC +CAGCACTTTGAGAGGGAGGACAAGGTGGGCGGATCACTTGCGATCAGGAGTTCAAGACCA +GCCTGGCTAACATGGTGAAACTCTGTCTCTACTAAAAATACAAAACTTAGTTTGGTATGG +TGGCCCACACACCTGTAGTCCCAGCTACTTGGGAGGCTGAGGCACGAGAATCGCTTGAAC +CTGGGAGGCGGAGGGCTGCAGTGAGCTGAGATCACACCACTGCACTCCAGCCTGGGCAAC +AGAATGAGGCTCTGTCTCAAAAAGAAAAAAAAAAAATTTCAATTCTAAGTCAATATATAA +ATTTAATGTGATCCGAATATAATTCTCAAAAAGTTTTTTTTCTGGAGATAGGCAATTGAA +ATGATCATATAGAAAAATAAATATGAGAAGATAGCTAGGAAAACTAAGAAGGAAGGGCTC +TGAGGAGATACCAGTCCTGTAAGACATTAAACCACATTACAAAGCTGGTATGATAAAGAA +TATGGTTGTGGAGCATGAATAGACAGACTAATGGAACAGAGTAGGAACCCCAGAAATAGA +CACAACTACAAATAGAAATTCAGTGTATGATAAAGGTGGTACCAAAAGTTACCAGGGAAA +AGCTGGGTTTTTAAATAAATGATATTAAAACAACTGAACATGCCAAATCTGTCCAGCTTA +GGGAGAAAAGAAGAAAGAAAAACAAACAAAAAACTGGACAGCCATTTGGGAAAAGATAAA +ATTAGATCCATTCTTCACACGATCTTTTCACACAAGCATAAACTCCAAATAGATCAAAGA +TCTAAATGTAAAAAACGAAACTAAAAATAGTGGAAGAAAACGTGGGCAAATTTCTCCATA +AAATGGGTGTAGGAAAAGTCTTTCTCTCATTATGACTCAAAATCTAAATGAAATAAAAGA +CTGATAAATTTGACTACATAAAAAAACTTTTGCATGACAAAAAAATCACTGTAAATAAAG +TTAAAAGACAAAATACAAATTGGGAGAAAGTTTTCCCGACATACATCACAGACAAATGGT +TACTATCCCTAATACAGCACATAAAACTGTCTTTAAAATTTAGGAGGACAAAAAGTCCAA +AAACCCAATAGAAAAATGGCCAAAAGGCATGAACAGACAATTCAGAAAGATATAAAAGTG +GTCTACATATATATGTGTGGGTCACACCTGTGGTCTCAGCTACTTGGGAGGCTGAGGTGG +GAGGATGGCTTGAACCCAAGATGTTAATGTTAAGGCTGCAGTGAGCCATTTTCACCCCAC +TGCACTCCAGCCTGCCTGACAAAGAGGGACCCTGTCTCAAAAAAAGAAAAAGAAAAAAAA +AGCATATATATATATAAAGATATATATAAAGAGATATATATATAAAGAGATATATATATA +CACACACACATACATAAATGTTTAACTTCACTTAGAGAAATGCAGATTAAAATTACACTG +GGCCAGGCACAGTGGCTCACACTTGTAATCCTAGCACTTGGGAGGCTGAGGTAGGTGGAT +TGTTTAAGCCCAGGAGTTTGAGACCAGTGTGGACAACATGGCGAGACTCCCATCTCAACA +AAAAATAAAAAAAATTAGCCAGGCGTGGTGGCATACACCTGTGGTCCCAGCTACTCCAGA +GGCTGAGGTGGGAGGATGGCTTGAGCCCAGGAGGTCAGGCTGCAGTGAGCTGTAATCACA +CTACTGCACTCCAGCCTGAGTGAGACACTGTCTCAAATAAATAAATAAGTAAAAATAAAT +AAATAAATAATAAAATTAGGCCGGGCACAGTGGCTCATACCTGGAATCCCAGCGCTTTGG +GAGGCTGAGGCAAGAGGATCCCTTGAGCCCAGTAGTTTGAGACCACCCTCAGCAACATGG +GGAAACCCTGTCTCTACAAAAAAATAAAATAAAAATTAGCCAGGCATGGTGGCACACACC +TGTGGTGTCAGCTATTTGGGAGGCTGAGGTGGGAGAATTGCTTGAGCCCAGGAGACGGAG +GCCGCAGTGAGCCTAGATTGCACCATTGCACTCCAGCCTGAGTGACAGAGTGGGACTCCA +TCTCAAAAAAAAAAAAAAAGAAAAAATTGGAGGTTGAATTGAGACTTACCAGCGTGAACT +TTTATAACTCTTATATTTCCTAACTCTGAAAGGGCTTAGAAGCAATGTCAAATCAGTTGC +AATGAGCACACCTAAAGCCTTATCTTGGTTTTTACTCCTTAGAGGAATGTCTGGTCCCAG +AGCTGGGGTAAGGAAAGTTCAAAATAAACCTCGAACATCTTGTTAAGCCAAAGTGAGAAA +GTGTTCAAAACATGATGGGAGATTGTTAAATGCACACAGGACCCAATTTGAACGGGTTCC +CCCTGGCCAAGTGTGAGAAAATGTGAGCACCAAGCTAAGAATATAATGGATTATAACCCT +GGTTATAAAACAGGAATTCTTTAGGTCATACTGATAATCAATCAATCAATAAGTGTGGGA +GGTGCCCTTCCTTATACCAACTTATACATGTAAAGGAGTTGTGAAACTGGAAAATCACCA +TTCTCAACCATCCTCGTAAACGTTGGTCCAAGCAAGAATAATTAATGAATGCTAAATCTA +GGGGGAAAGTTTGGTGAGGAACAGAATATTTATATAGTTTCAAAGTCTCTCTCCACAGAC +TGCTAATTAGTTACAAAAGGTAAAACAGTAACTCTTCAGTAGAGAAAACAGACAACATCT +TGATCAAAATGATCACCAATGAGGAACAGAGGAACAAAGTGTGCCTCTGGATGTGATACA +CTGGAAAAAATACATTATTTGGGTTGGGAATAAGTTAGCTGAAATCTAATCTTAAGGAAA +TGTATAACAAACTCAAATTGAAGAACATTTGTAAAATAAGGAGCGATATAATGAAAGCTA +ATAAAAGGCTGAGGAACAGTTGCAGACTAAAGAAAACAAAACAAAAACAAACAACAAAAT +GCAAAACATGATCCTGGACTGGAGGGAAAAAAATTGAAAAAGTTGAGGTACAAGACTTAT +GATTTTCTCAATGTTAAATTCCTGAATGTAATAACTGATTTATAGCTATATAAGAGAATA +CCTTTGTTCTCAGGAAATACACAAATAAGATGATGGGGCTAGGCGCAGTGGCTCATGCCT +GTAATCTCAACACTTTGGGAGGCCGAGGTGGGAGAATTGCTTGAGCCCAGGAGTTCAAGA +CCAGCCTGGACAATGTAGCAAGACCTCCATCTCTATCTATTTATATATATATAAAATTTT +TAAAGATAATAAGAGGTAAAGGGAAATGATATATGCAACCTATTCTAAAATGGTTCAGAA +AATATATATATATATATATATATATATGAAGGGAACGAAAAAAGTATATGTGGCAAAATG +TTAAACATTGGTAAATTTGGGTAAAGGATATATAAAAATTCTGAATATTATTCTTGCAAT +TTTAAGTTTGAATTATTTCAATGAAAAGTAAAAAACAAAAGTATGCCAAGTCTTAGTAAT +CAGTTTCTAATTTCAGAAATGCATACCCTGAAGAAAAATGGTATCTCATGTTTGAACCAT +TCATTCAAGTATTTACTGAATTCATTCAACAAGTATTTACTGAATGTGCCAAGCAGTAAA +GCGAGACAGAATACCCCAGTCATGCCCCTACTCTTAAGTGCTCTTACAGAGATAGGCCTG +GCTCTATGTGTTTTTTCCAATTTTGCTGGAGTCACCTCATCTAGGATCCAAATATCAGGG +GTGGGTATCAATGCAAATCCCTGAATCATCGTCATTGTTTTTATCATTGTAGTTGTCATT +ATCGTTGTAGTGTTTTTCTTCTTTAAATAGCAAAACCCCTTCCTAACACTTGAGAAAAGG +TGAATTAAGAGAAACGAAGTTATATGTACCTTTGTTTAAAGTCACGAAGTAGTAGTAATA +GCATCCATTTCAAGACATTTCATTTTATGAGGACAGTAATTGTTCACATTTTAAGACTTG +CTCTGATTTTGCAGAGCTTTTGAAGACATTTTCCCCTTGTTTGGGAATCAATATGAAAAC +ATTGATTGTCCTGCAATTATCAATGTTACATTGTCTCTGGAGTTTTTGGCCTTGTTTCAA +TGCAATAAATCAAGTTGTAGATTGCTGGTGGCCTTAGCAGAGCAATTATCACTGCAGCAC +ATAATATCCAGCTTGCTGCCTTATTGTGATTCAGAGACCTAGTCACAAGCTTGCTTTTTG +TCTAAGAGCCAACAACTAAAAACCCAAGTTTCCATCAACAGAAGGAATAAATTGTGGTAT +ATTCATACATGGAGTACTATGCAGCCACATAGGAGCTAACTACTGCTACATATAATACGG +AGTAATCTCAGACATGATGTTGAACAAAAGCAGACAAGCACAAGTCAATATGTGTGCATT +TATTTATATGAAATTCAAAACAGCTACTACAAATATAGGACATAGGAAGAATGTCTACCT +TTGGGGAAGGGGGCAAATATTAACTGAGTAGGGACCCAAGGGAGCCCTCTGAGGTACTGG +AAATGCTCTATATTTTTATATGAGTGGTTACAGGGTATAATCATTGGTCAGGGCCAGGCT +CATGCCTGTAATCCTAGCACTTTGGGAGGCCGAGGCGGGTGGATCACCTGAGGTCAGGAG +TTTTGAGACCAGCCTGACCAACATGGCAAAACCCGGTCTCTACTAAAAACACAAAAAATT +AGCTGGGTGTGGTGGTGGGCGCCTGTAATCCCAGCTACTCAGGAGGCTGAGGCAGGAGAA +TCGCTTGAACCCGGGAGGTGGAGGTTGTAGTGAGCCGAGATCCCGTCACTGTACACCAGC +CTGGCGACAAGAGCGAAACTCCATCACACACACAAAAAATTAATTAAAAATAAATAAACA +TTGGTCAAAAATCATAAAGCTGTATCAACTGTATATAAATAATTCAATTAAAATATCATG +CATAAAATCTGGGTGTAATAAAAACAAAGAATAATTTTTTTAAAACCCAAAGCAAGGCAA +GGGGTGATGTTACCAAACTGCCATGTATCAGAGATGTGATTAGAAGGAAATCCTTCAAGG +GGAGCTTATTTATGGTACGCTAGATGTCTTCTGGCTCCATTCACACATGATAAATAACAC +CACCTCTCCAAGTCCACTGGTTTGTTTCTTCAAGGAAAGAGTTGGAACAGGATCAATGTT +TACACTCACATGACACAAAACATCTATGTCATCTCCATCTGAGATCAGATGAAAGCTAAG +TTTAAATGACAGTAGTTGTTATTCATTAATATAATTGGTAAAGAAAATATCAAACATTCT +TGTCTGCATAAATAGCAAGACAAAAGCAAAATTAAACAAGTTAATAGCACAGACCCTGAA +GTCAGAGAGCCAGGAGTTCTAGATGGGGCTTTGCTACTTAAGTGGCAGTGTGTGTTGCTT +ATCTGAAAGAAAACATTACCAATTTGTTGGAAAGTTCTTCTTTAGCAGTAGTAATCGGTG +TTTTATCCAACATATTTCTTAATAACTGTTGAGAAAAGGTTGAGACATCTTCCCAATTGG +CACAGAAGTGCAATACAAGGCCAGAACATTAATTTCACGTTTTATTAAAAATTCATGGTA +ATTAAAAGGTTTTCGTTAAGTCTATTTATCAATTCTAAGAGAACCTAGAACAGGAATATG +AACAAGCTCAGCAAAATGATCACAAGGCCACTAAAAGAATGTCTGATATTCCCCAGGCAG +TCAAAGATGCTCAAAGGAAGAAAAGTATCCTGACTTAGAATTTTATACCCAGCACGGTTA +AAGATCTCCTTTTTCTTCTGTTTTTTAACTTTTTTTCTTCTCTTTCAAGACAACTCGTCA +CTAGGATTCCTTTTCTTCTAAACAATGACTTTCTCATTCTTTTTGGCTGTCTTAAAATGT +GACAACAAAAAAGCATCTTTGCACATTAGGAAGCCGAGGCAGGCGGATCACTTGAGGTCA +GGAGTTCGAGATTCGCCTGAGCAACATGGTGAAACCCCATCTCTATTAAAAATACAAAAA +TTAGCTAGGCATGGTGACATGCGCCTGTAGTCCCAGCTACTTGGGAGGCTGGGGCAGGAG +ACATGCTTCAACCCGGGAGGTGGAGGCTGCAGTGAGCTGAGATCGCACCACTGCACTCCA +GCCTGGGTGACAGTGAGATTCCGTAAAAAATACAAATTTAAATTAAAAAAAAGAAAAAGG +AACTTTGTTTTTGCTTTATATTTCATGCTTTAATAAACATAAAAATTTGCTGTCTCCCCA +TCCCCCACCTCTCAGACTGAAGGTAGTCCAAGTACCTGAGATTTTATGGAGTTTTACTTT +TTTATAGTTTATAGGCAGTTTATGCCAAGCCTAAAAGTGTGAACTCTAGTCTGTATGTAG +GCTTGGATTTAAAGCCCAGTTCCACCTCCACTTACTATGTGACTTTGGACAAGTCGCGGT +TCAGTTTGATGCTTCAGTTCCCTCATCTGTAAAATGGGAATATATTACTGAACCAATTTC +ATAGGGTGGTTTTAAGAATTAAATGATATAGTGCAAGTAAAGAGTTTACTTGTTAAGTAA +ACACATACATATACTCAATATTAGCAGTTACAAATGTTAATTCCGAGTTGGCTCTGGTAA +ATTTTTTAAAAATTGGTTGATTAAAAAACAGGCATATCGGCCGGGCACAGTGACTCACAC +CTGTAATCCTAGCGCTTTGGGAGGCCTAGGCAGGATGACTGCCTGAGCTCAGGAGTTTGA +GACTACCCTAGGCAACATGGTGAAACCGTCTCTACTAAAAATACAAAAATTAGCCGGGCA +TGGTGGCAGGCGCCTGTAGTCCCAACCACTTGGGAGGTGAGGCAGGAAAATCATTTGAAC +CCAGGAGACGGAGGTTGTAGTGAGCGGATATCGCACCACTGCACTCTAACCTGGGCGACA +GAGCAAGACTCCATCCCCAAAAAAATCACTACTCTATACTTCTAAGAATCTTCTAAGAAT +CCCTGCTTCTTTTTAGTGCACATGAGCTTGGTTCCTCAGGCAATTATTTTATAATCTTCA +TTGCTGGCCATAATTGCAGTGCCACCAAATTACCACTGCATCACAAATGGATTTGTAAAG +AATAGTCACCCATACTTATAAATGATTTGCTTATAAAAATATCTGTTAAAGCCGGGCGCA +GTGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGCAGGTAGATCACCTGAGCTC +CCGACCTCAAGACCAGCCTGACCAACATAGAGAAACCCCGTCTCTACTAAAAGTACAAAA +TTAGCTGCATGTGGTGGCACATGCCTGTAATCCCAGCTACTCAGAAGGCTGAGGCAGGAG +AATCGCATGAACCCGGGAGGTGGTGGTTGCAGTGAGCCAAGATTGTGCCATTGCACTCCA +GCCTGGGCAACAAGAGTAAAACTGCATCTCAAAAAAAAAATCTGTTAAAAATATTAAGTT +AAAAATTTAAAGGACTTGTTTAGCATATAATCTGGCATTTAATCCATTTTATATTATAAC +TTTTTATTCTTAATAGTAAAAATGTCTTCTACTGATTTAAATAGTTTGGGAAATATTAAC +ATTTAGGGGCTGATAAAATAATTTTGAATGTCAGGCTGGCCATCTACCTGGCAATACGAA +ATAAGCATAATAAAAAATATTCCATGTACCACACATTTTTTTTTTACTTGGGGTGGGGTA +TAGAAACAAAAACCCATCACCAATCATAAATCCATCTGTTCACGTATGCCTTATCAATGA +TCATGTATCTTGTGGGAACTTTCTGAAAAGGACAAATGTTCCAACATGTAGAGCTTTTTC +TCTGCAGAAAAAACATCAGAGCTAATCAAAAGCCCATGTTGTTTCCTTTTCTGGGGATAT +TGTCAGTAACAAAGTAAATAAATTGCATGTTTTTCTACCTTTTTAGATAATACAATATTT +TGCAAACTTGCCATGATTGTGAGGGTCAAATAAACGAATACTATCTAAAATTTAAAAATT +AGGTTATCCTGGCTGGGCGCGGTGGCTCATGCCTGTGATCACAGTACTTTGGGAGGCCGA +GGCGGGTGGATCACCTGAAGTCAGGAGTTCCAGACCAGCCTGGCCAACGCGGCGAAACCC +GTATCTACTAAAAATACAAAAATCAGCTGGGTGTGGTGGCACGTGCCTGCAGTCCCAGCT +ACTCGGGATGCTAAGGCAAGAGAATTGCTTAAATCTGGGAGGTGGAGGCTGCAGTGAGCC +GAGATTGCACTACTGCACTCCAACCTGGGTGACACAGCGAGACTCCATCTCAAAAAAATA +ATAATAATAAAAAATAAATAAAAATTAGGTTACCCTGCAATTCTGCCATGTATCTCCCTA +GCATGTGAAACTAGGTGGTAGAGAAGATACAGCAACAGGAGATGTATCAAAGTGATCTGA +GTGTTACAGAAAGTGGTTAACTAAAAACCCTTAAATCTAACTTAGTAGAAGACAGGCTAT +ATTTACTGAAGAGGGAGAGTCAGTATGAGGCCTAAAAATAGGAGACAAATAATTCATTGC +CAGGCATGATGGCTGACACCTATAAGCCCAGCACTTTGGGAGGCCAAGGCAGGAGAATCG +GGAGTTCGAGACCAGCCTGGGCAACAGATCAAGACCTCATTTCTACAAAAGTAATAAATT +AACCAGATGTGGGAGTGTAACTGTAGTCTCAGCTACTCAGGAGGCTAGGCGGGAGGATGG +CTTGAGCCCAGGAGGTTGAGGCTGCAGTAAGCTGTGATCACACCACTGCACTCCACCCTG +GGTGACAGAGCAAGACTCTGTCCCTATAAAAAAAAAAAAAAAAAAAATTCATCGGTGTAG +GGCCAAGTGCAGTGGCTCACACCTGTAATCCCAGTACTTCAGGAGGCCAGGAGTTTGAGA +CCGGCCTGGGCAACATAGCAAGACCTCCATCTCTACAAACTAAAATATTAGCTGGATGAG +GTGGTGAGTGCCTGTAGTCTCAGCTACTTGGGAGACTGAGGTGGGAGGGTCTCTTGAACC +CAGGAATTGCAGGCTGCAGTGAGCTACAATTGTGTCACTGCACTCCAGCCTGGGCAACAG +AGACCCTGTCTCTATAATACAAAAAATTAAAAAAATTCATTCGTGTAGCACTGGCATTGT +CCAAAGGTACGTCTGCCCTGACTGGTTTATTCAAAGATGTCCCCATGACTGGTTAGGTCT +CCTAGCAGAGATCCATGCAGATTATCATAGCTGGACAGTGTTAGGCAGTATATTGACCAG +CTCCACCCATGGTGCTTCCAACTCGGACTTAGGATTTAACTTTGCTTCCATGACAACTTG +TCTAGTGCACTCATTAAACGTTAAGTATCCAGATACTCTTCAAAGTTATATACTTGCTTT +CAGCCAGGCATGGTGGCTCATGCCTGTAGTCCCAATACTTTGAGAGACTGCGGCAGGCAG +ATCACTTGGGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGCGAAACTCTGTCTCTAC +TAAAAATACAAAAATTTTAGCCGGATGTAGTGTTGTGTGCCTGTAATCCCAGCAACTCAG +GAGACTGGGACACAATAATTGCTTGAACTCAGGAGGCGGAGGCTGCAATGAACTGAGATC +GCGCCACTGCACTCCAGCCTTGGTAACAGAGCGAGACTCTGTCTCAAAAACAAAAAACAG +ACCAAAAAACAAAGCCATATACTTGCTTTAAATGAATAATCTGGGATCAAGATTTTAAAC +CAAAATAATAAGCAATTTTCAAAGTACTCTCCATTAACATCTCTCACATAACCAAAGATA +GCATACTATAAACAAGGCACATTACTTAAGCTTATTTCATCTATGCAAGTCTTAGCATAC +GTGTTGAAACAAAGAAAAGATTCCAGAAGTTTCCAATTAACCATTATACATCTAGTATCC +ATAGAAAAATGTCACCTGTTAGTTTGTGTCAAAACTGTCAAATGATGCAGTCATACACAT +GCTTTAAAAGATACACGGTAGCCCAAAAAATGTCAGTTGTCTTGTTCTGTTTTGCATCTC +AAATTCTGCTATGAAACTAGGAGTTTCAAACAAACCACTGTGGATTATGAACTACGTTAT +TTACCATATACTACAGTCAGTTCTTTTTACTCATAGCAGTTATGTTCTATGAAATCACCA +TGGGCCGGGCGCCATGGCTCACGCCTGTAATCCCAACACTTTGGGAGGCCGAGGAGGGTG +ATCACCTGAGGTCAGGAGTTTGAGACCAGCCAGGCCAACATGGTGAAACTGTCTCTACTA +AAAATACAAAAATTAGCCAGGTGTGGTGGTGTGCGCCTGTAATCCCAGCTACTTGGGAGA +CTGAGGCACGAGAATTGTTTGAACACGGGAGGCAGAGGCTGCAGTGAGCCGAGATCGTGC +CACTGCACTCCAGCCCAGGCAACAAGAGCAAGACTCTGTCTCAAAAAAAAAAAAAAAAAA +AAAAAAAAAAACAAAGAAATCACCATGAACACTGAATTATTAAATACAGGTTGAGTATCC +CTAATCCAAAAAGCTCCAAACCCCTAAACTTTTGAGTGCTGACATGACACAAGTTGAAAA +TTCCACACCTGACCTCATGTGATGGGTCAGTCAAAACTTTGTTTCATGCACAAATTTACT +GAAAATACCGTATAAAATTACATTCAGGCTGTAACATGTATGAAATAAATTGTTTAGACT +TCAGTCCCGTCCCCAAGATCTCATTCTGTATATGTAAATATTCCAGAATCCCAAGCATTT +CTGAAAAGGGATAATCAACCTGTACTGACAGGGTTAGGTTCCTGTAAGCCTGTGACATTT +CCAGCAATTAATACATGACCTTGTTTTATGTGTTTGTTAAGATACCTTAATATACATTAA +TACTGAATTCATGTAACTCATGTCACCCATGCCTGAAAAAAAGCCTCCCTAACATCCATT +TTCTCCAAAAGGCTCATCTCTTCCTTCTTGTGCTAAGGAACACCAGGTAACACTTCTGCG +CTATGCTTGGGGGCCATTTTAAACAGCAAAATCCACCCACAAAAGGCACAAAAATGTCAA +GAACATAGCACTCAACAGACCATGAAAGGGATACTCGTCTGGGAAGTGTGTTATCAGGTG +ACGCAAACTTTTTGTTGCTCTGCACACATCCATGAAAGCAGCATGCACACTGATTTGGGG +GTTACAAATAAATTTTAGTGAGTAGGCAAATTTGTAAATACGGAATCTGCAAATGAGAAT +CAACTGTTTCCTTAATTCCTGCAAGAATCCAAATGCCTACTCCCCAAATCTGTTGGCTCT +GGCCACTTAAAGTTTGCTCTATCTGAAAAAGCAGACATTTCAGGAACAGATGAATATGAC +TTATCTTCGAATCTCACAACAAATACTGACTTCCAATCAATCAGCTACCTAACGTATAAA +GCTATGAACCCAACCTGGCACTAGATTTTGGTGTGTGAACTAGTGTGTGAACTTTATAGA +TTTGACTTCAAGTGTCTCAAAATAGCCGGCTCTTTTAAAACCTCAAAATTTGAACCATTT +TGTATTACAATTTTGAAAAAATATGGTGTTTCTCTGCCTTAACACAATGAAGAAAATCTT +TCAAAAAAAAAAATTGTAATGAAGCATCAGCCCCTGAGAGGGTATGTCTGTTGTGAGGCA +AAATACAAAATGATCAGGATCCCCACTGGATGCACTGTTCTATGCTAAAGGGTAGGAGGG +TGGAGTTTGTATTATCTTGAGTTTCAAAACAAGAAGCCAAAGCGAAAAGCATTCTAGGTA +CAGAAGCATCACTAGGCTTCATCAGCATTGAGGGCTGCCACTGTCACAAGCTAGGGTTTT +GTTTAGATTTATTTAATCCCGAAGGTTAATAGAATTGTTTGTTTAGCATGGAATGAGATA +ACCACACGTTTAACTTAGAAAGCTAACTCTAGCAGTAGTCCACAGAGAATGATCGGTTAG +AAATTAAAACCTAAAAGTGTAAACTGCCTGGGTTATCAGTTTTATGCAGATACCCTATAC +TCCAGGCTAGATCTTCTAAATCCATCCTCCTAAAAGAACCCCACATCTTCACCTTTAACA +AGTACTTTGGGTATTACACTAAAATTAAGCCACAATCATGAACTACCAAATTAAAGACGT +TACAAGAATAAGGTTTAAAACTAATCATAACTTTTAACACTTTAATATTAAAATCATACC +AAAGCCTATCTTATCTACATCCTCTTCAAGAGTAGCTATCATTGTTTTATATCATGTAAG +GGTTTAAGCTAATAATCTCATAGCCTAGAAACCTCAATATAATCATCAACTGGCAGGCCA +GGCATGGTGGCTTATGCAGGAATAAGCCTTATGCTTATGCTTGAGCCCAGGAATTCGAGA +CCAGCCTGGACAAAATAGGGAGACCCAACCTCTACCCGCAAAAAAAAAAACCCCATAAAC +TGGCTTATCTTCAAAAGTGGATGGGTGTCAGTCTTGTACATGAAATATTAAGATCATGTA +ACAAATACATGTAACAAATTGTTTCAATAATCCGTATGGAAACCTTAACTCATAAAATGC +ACTACAGGAATTGTCTTGTGCCTTTTACATAAAACCAATAGACCCCCTGAACTTAACAGT +ACATTTTTCATAAAAGATTCTTATGTCGGCTCAGCACCATTAAGATATTACCTATTTATG +CATGGCAATTATAAAGACTTTGAAAAAAAGCAAATCCGTGCACTGTTTAAGGAATTTTTA +TTAAAGCAAGAATTTTATAATCCAAATTACGTTTCCTTGCTCAGTTATCAATTCTGTTAC +TTAAAACAGAACTGACATTCTGAGCTATTCCACAGTAAAGAATTACAAAATTAAAGAAAG +GAATGCTTTAAATTTTTGTACTTTGCTGAAAATTCTTTTTCCCAGGGTCTATAAAACATT +AATTTGTTTTTATATTTTACTATTTTTTTGTGTTTTTTTGTTTTTAAATCAATAAGTAAT +CTAGGACTAGCATTATGTTTGCTAGACCTGGCATTTGCTCGGTACATAAGGTTCAAAGTT +TCCTTTCCTTTTTTTATTTATTTTATATTTTGCAATGTTTTTTTTCCATAATATTTAAGT +TTTTCGATGTTTAGATATTTTTCTTCGGTGAAGCACAAGTTTCTTTTCATGGTCCCTGAT +CAATCTGTAAATGTTAAAAAAACAAATTAAGACCAGGACTATCACTTGTCAGTAGCAAAT +TAAAGCCCTTAGCCAAATGCAATGTGGTTGTTTTTATCCATAGTTTTACTGGAACACAGC +CATACCTGTTCATTTGTATACATACTATCTATGGTTGTCTTGACATGGTAACACTGGAAC +AAGATCATTTCAGAGATAACACAGTCCTCAAAGCCCAAAATATTTCCTATCTGGCCCTTT +ACAAAAAACATTTGCCAATCCCTGGTCCTGATCCTGGCTGCACTACTCAATTTCTTGGGA +GTGATGAAAGACAGTAGTAGAGACCCAAGGGCACCACCCAAAAAGGAAAGGTAAAACTAT +GAAAGCCAACCTGTGACAGGTCATTTTATATATATATTACTATACAAAATCTGGCAGGGC +GCAGTGGCTCACGCCTGTAATTTCAAGACTTTGGGAGGCCGAGGTGGGCGGATCACTTGA +GGTCAGAAGTTCCAGACCAGCCTGGCCAACATGGCAAAACCCCAAGTCTAGTAAAAATAC +AAAAATTAGCTGGGCACGGTGGCAGGCATGGGCCTGTTAATCCCAGCTGCTCGGGAGGCC +GAGGCAGGAGAATTGCTTGAACCTGGGAGGTGGAGGTTGCAGTGAGCCGAGATCGCGTCA +ATGCACTCCAGGTTGGGCGACAGAACGAAACTCCATCTCAAAAAAAAAAAAAAAAAAAAA +CACCACCTGAAAGTCCTGGGATTTTAAAAATCCAACAGTTAACGGGTAAAATTCCTTTAA +TTCCTCTATAGTTAGTTCCACTTTTCCTTGAAAAATTAGCAATACATTTAAATGAACTGT +AAAATGATCTTTTGCTATGTACATTTCAAAATATGCTCAACAAACTTTATAAAAGATGAA +GAAAACAAGCTTAAAACAACAAACCAGAGGGAAAAGCTCACTTTAAACAGTTGGAACACC +GGTGGCACTGTTAACTGCTTTCTGGGCAGCCTCTTTAGCTTGGTGGGCTTGTAGTACAGC +TACAGCTTCATCAACCTAAAAAAGGGGAAAACAGATAAACTGGTTCAGGAAAGGAATGGA +AATAAAGAGTTTCATAATGGTAACATACCAATTCCCAACAAAGATAAGTTTCTTCCCTCA +AATGAAAGTATAAATTGTTACACTAAACAACTATATCCATTCAATTTTGAGTTCTATTAC +ACCACTATTCTAGAATTATGAATCGCTCCCCTGCACTACTCTTTCCTTGTCCTCCCCACA +CTCGAAAAATATTTCTCTTTCTCCACTAGAGAAAGCAGCAGCAGTTGAGAGTATGGCTGT +TGGAGCTGATGGGATTTGAAGCCAGGCTCTGCCACTTAAGAGCTGTGTGAGCATTTGGCA +AATTATTCAGCCTGTTTCAGTTTACCTATCTATAAAATGGGGATAAATAGCGCCACAGGT +TATTATGCAGACTTTACAACTGTACATGGCTTATATATAACACGATGTAAGTGTTCTGTA +CAATTAAGTCCCCATAAAAAGCCACGTAATAACTGTGTAAGAGGCAACTTGGTAAATAAA +TTTAAATCACCTTAGAACGGAGTGACTCTGGAGACTCGAGCATATGAAGAAGTTCTGAAT +TATCAATCTCCAACAACATGCCAGTGATTTTACCAGCAAGAGTAGGGTGCATGGCTTGAA +TAAGAGGAAACAGCCGTTCACCTAGGAACAGAAACATTCAAAAACTCCCTTCAATAAAAA +AAAGTTTTTAACTGCATTGAATTACCACATTAAACTGGGGTTTAAGAACCATACTTCTGT +CTCACGTATATAATAACCCATAATCCACAATTTCATTATGTCTTCATGGGAAGACAGAAT +AAAATCTGCCACAAGGCAATTAACTCTTGATATTATCAGCTTGCCAATTAAGCAATGTTA +CCATTAGGTTGTTAAATCGGTGTTCAGGCAAAGTCACAAGTTTTCTTCTCATTTGCTTCA +AATTCCTTCTCTCAAAAATGTAGTGAGGGCCCATGGTGAGTAATGCCCTACTACCCTATT +TATTACTAACAATACATTTTCTTATTGGCTTTCCAGTGGTTTTAATTAGGCAGACCAACT +GTACTATCATAATCATTCATGCCAATTCAGATCAATTCCACTGCCCTAGCTGTCAATTGA +TTGACCTAGTGCCTAAGTGATTCCTATATTTTCTAGTCTTTCTGAACTGACAAGGTGGGA +CAGAAGTACTCACCCAACATTTGCTTTTGCTCTTGAGGAGGGGCAGATGCCAACATGGAA +GCAGTCAAAGGTTCCTGACCTTGTACATGAACAGCAGGCTAGACAGAAAATGAGAACTCT +TAAGTTTAAAGCACAGAAAAAGATGGCAAATACAAATAGTCATCAATGGACATCTGCTGA +AGTGGTAGACTTCCATCGAAACATGAGGTGGAGAAGTTGAGTGAGCGAATTAGAAAGAAG +CCAAAGTAGTTATTATATACTATGTATCACAGATACATTTTTTTTCTTTTTGAGATGGAG +TCTCACTTTGTCGCCCAGGCTGGAATGCAACGGCACAATCTTGGCTCGCTGCAACCTCCG +CCTCCGGATTCAAGCAACTTTCCTGCCTCAGCCTCCCCAGTAGCTGGGATTACAGGCATG +TGCCACCAAGCCTGGCTAATCTTTATATTTTTAGAGCTGGGGTTTCACCCTGTTGACCAG +GCTGGTCTCAAACTCCTGACCTCAAGTGATCCACCTGCCTTGGCCTCCTGAAGTGCTGGG +ATTACATAGAGGTGTGAGCCACCACGCCTGGCCCATAGCTACTTGTAATAGTTGTTTCAG +ACCAGGCGTGGTGATTTAGGATGTGAATTTCTCGCTGCTTGTCCAATTCCAAAAGCGTAA +GACATTTTACATACTATCATATTAGCAGAATGTTCCAGATAGGCTAAGCTCTCAAGAATC +TATCATGCAGCTGTCTTCACATTTTTTCTTTTGAGACAGAGTCTTGCTGTCACCCAGCAG +GGATTACAGCTTGCTGCAGCCTTAAACTCCTGGGCTCGAGCAATCCTCCTGCCTCAGCCT +TCCTAGCAGCTAGGACTACAGGCTTATGCCACCACACCCAGCTAGTTTTCTTTGTGGAGA +CAGGGTCCTGTATGTTGCCCAGGCTGGTCCCAAACTCCTGGTCTCAAGCAATCTGCCTGC +CTCAACCTCCCAAAGTGCTGGGGTTATAGGTGTGAGCCACTGTGCCCAGCTGTCTTCACA +CCTTTGATTTCACCCAAGAAATGTGATTTTTATTAAGAAATCATTAAATCCATACCTGTT +GCATTGTAACTTGTGGCTGTGCATTAAGATGTTGCTGAGGATTGCGAACTCCTGCAGCAT +ATTTATACTGTGGAACGGTGCGGACAGCAGGAGTAGCTGCAGCGGCTGCAGCTGCAGGAC +GTGGACCCATTGTCTGTGTTGATGTGTTAGCTAAAAAATAAGAACATTTTGTATTTTTAT +CTTGCTCTTTCAAATTGGTGATCAATTTTTAAAGGAAGGATTAAGACTCACCAACACGCT +GTGTTGACATGACTCGTGGAACCTGTGAAGAAGCTGGTCTCATAGTACTAAATGGTGGTC +TAGGAGCAGCTGGGCGGATAGCACCGGGCATATTTTGGAATGCTGCATTTTAAAGATGTG +AATATACATTAACTGGGAAAACTTACTGAGTGAAAAGTGTTTATGCTGTCTTCTTCGATC +TGAGGTTTGCATAAAAGACTAAAAAGTGACAAAACTTTTTAAAGCTGAGTCTTAACACTT +GCCATTTTCCCAGACTCAGAGCATCAATAAGTAAAAACATTAATTCATACAAGGACGAGT +ACTTATATGTAGCGACCAGCCCCACAGGGTCGGTGGGCTTCTCCCTGTATGCAGCGACGA +GAGAGTGCAGAAATAAAGACACGAGACACAGAGATTTAAAAAAAAAAGACAGCTGGGCAC +GGGGGACCACTACCACCAAGACGCGGAGACCAGTAGTGGCCCTGAATGTCTGGCTGCACT +GTTATTTATTGGAAACAAAACACAAGGGGCAGGGTAAAGAGTGTGAGTCATCTCCAATGA +TAGGTAAGGTCACGTGGGTTACGTGTCCACTGGAGAGGGGGCCCTTCCCCGCCTGGCAGC +CGAGGCAGAGAGGGAGAGGAGACAGAGAGAAAGACAGCTTACGCCATTGTTTCTGCATAT +TAGAGACTTTTAGTACTTTCACTAATTTACTACTGCTATCTAGAAGGCAGAGCCAGGTGT +ACAGGATGGAACATGAAGGCAGACTAGGAGCGTGACCACTGAAGCACAGCACCATAGGGA +GACGGTTAGGCCTCTGGATAATTGCAGGCAAGCCTGACTGATGTCAGGCCCTCCACAAGA +GGTGGAGGAGCAGTCTTCTCTAAACTCCCCAGGGGAAAAGCAGACTCCCTTTCCCGGTCT +GCTAAATAGTGGGTGTTTTCCTTTGACACTTACGCTACTGCTAGACCTCGGTCCGCCTGG +CAACGGGCGTCTTCCCAGACGCTGGCGTTACCACTAGACCAAGGAGCCCTTTGGTGGCCC +TGTCTGGGCATAACAGAAGGCTCGCACTCTTGTCTTCTGGTCACTTCTCACTATGTCCCC +TCAGCTCCTATCTCTGTATGGCCTGGTTTTTCCTAGGTTATGATTATAGAGTGAGGATTA +TTATGATATTGGAATAAAGAGTAATTGCTACAAACTAATGATTAATGATATTCATATATA +ATCATATCTAAGATCTATATCTGGTATAACTATTCTTATTTTATATTTTATTATATTGGA +ACAGCTCGTGTCCTCGGTCTCTTGCCTTGGCACCTGGGTGGTTTGCCGCCCACACTTATA +AATATACCTGAAACATAATCATGATAAAATTCTAAGTGCTCCCAGCCTGGCCAACAGGGC +AAAATCCCGTCTCTACAAAAAATTTAAAAAATTAGCTGGGCGTGGTGGCGTGTGCCTGTA +GTCCCAGCTACTTGGGAGGCTGAGGCAGGAGGATCACCTGAACCCGGGAGGTGAAAGCTG +CAGTAAGCCAAGACCATGCCACTGCACTCCAGACTAGAAGAAAGAGTGAGACTCTGTCTA +AAAAAATAAACTCTAAGTGCTCTTGGAATATAACATACTGTTCCACAGGACAAGACATAA +AATACCACGACTCTGATTCTCATACATGATTAAATGGAACGAGACCTTTAAAACTGTGGC +CTGACAAAATATGAAATTGGCTGGGTGCCATGGCTCACGCCTGTACTCTCAACACTTTAG +GAGGCTGAGGTGGGCAGATGACCTGAGATCAGGAGCTCAAGACAACCCTGGCCAACGTGG +TCAAACCCCATCTCTACTAATAATGCGTAAGTTAGCTGGGCGTGGTGGCGGGCACCTGTA +ATCCCAGCTACTCCAGAGGCTGAGGCAGGGAGAAATCGCTTGAACCTGGGAGGTGGAGGT +TGCAGTGAGCCGAAACTGAGCCACTGCACTCGAGCCTGGGGCAACAGAGCGAGACTCTGT +CTCGAAAATAAATAAATAAATAAATAAATAAAAAATGAAGAGCTGTACCTATTCCCAAAA +CTTTTATAAAGGGAAATCAAACCACTGTAGACATTACTATCTTAGCACTGCTTTTAAATG +CTATAAAAATGAACATCCATAACCACAAATTATGTGAAATGCAATAGTTAACCTAACATT +GACATAGAAGAGCTGATTTACCCAATGTGTTATTTTTAACTCAATCCCCAACCTTAATTA +AAAGAAAAAAGACTTACGATGAGGTCTGGCACCCTGAGCAGTCCAGCGAGGACTTGGTCT +TAGTTGAGCAATTTGGCTAGGAGGATAGTATGCAGCACGGTTCTGAGTCTGCAGGGAAAA +AAAGCACATGAGTTTATCAGTTGAAGAAAAAAGCAAATAATGCAATAAATTATATGTACT +TTTTCAAAACATTTACCAGGACTTCACACTCAAGCATTTTTTCCTACTCAATCATAATTC +CCCTTTCTTAATGTTTCACATTTGCGGGGCGAGGGGCACAAAAAACACTAGAAATGACCA +AATACGAAAACCTTCATGGTTCTGGTTGCCTTCTAAAACCTACCTGTGGGATAGCTGCCA +TGAAGTAACCTGAAGGAGGTGCTGGCTGGTAGGGGTTGATTACAGGGTTGGGAACAGCTC +GTACACTTGCCATTCTCTGCATATACTGGTTAGTGAGGTGAGCCTGGCGCTCTTCTTTGC +GCTGAGCTAAAGCTACATACAATGGCTTTGTGGCCACAATTCTACCGTTCATTTCTGTAA +CTGCTTTAGTGGCTTCTTCTGGGGAGGAGAAACATACAAAACCAAACCCTTTGCTGCGAC +CACCCTCCATCATAACCTATTAAAAAAAAGAAAAAAAAAGTTAACGTAATGGTAGAATGA +GGAGCAAAAAAAGAGCGTTACAATTTAGACAATTATAAATCACTGAATCAAATAACTAAA +CCCTGTTAATGCTTAATCATCTTGTATTTACCCATTGAGTTCACAATTTTTCCTTAATAC +CCAATTATTAAGGGCAAACTACACATATGCATTACCCTAGCCAGGTCAGAGAACTGACAG +AAGTGAAGGCTGCACAGAAACTTTTAAAGATTTTAGATACTGAATTTGATTGGATTTTCA +ATATTGAAATTTAATTATCTAAATAAATACATCCCAGGCCTACTAAATTGACTTTTGGGC +ACCACTGGAAGCATTTCCCAATTAAATTTTGACTATTCTAACAATTCAAGCTGACAAGAT +GCTTCACTATGCCTTTGAGAAAAAAGTAGTTGAATCTTACAATACCCACATCTTAAAATA +AAAGTTTTTACATTCAAGAGCAGAGGATCCATAAATATTACGGTATAAAGAACACTCAAG +AGGAAGGTTCTTCTAAAATTGATTGCAAAGACCTTTTAAATGAGCAATGAAGACTTGCAA +AGAACCACTCGCTAGGCCAGCAATATATATAAGCATGCTATAAAACTACATTAACAGTAT +GCGAGTGGCATAGGAACAAACGGTAATAAAACAGAGGCCAGAAATATACCCAAGCAATTA +TGGGAATTCACTGTGCTAAAGTTAACATTTTAAAGTACTGGGGAAAAAGGACTTTGGGCT +ACTCAATACATGACACACTGGGACAAATGAAAAAATGTAGAACTCTTAATTCACATTACA +TTGAAAAATCTTAAATGCCAGGTAGATTCTGAATCTGAACATAGAATGTAGAAATAGAGA +GAAAACCTTTCTAAGATGACACACACACAAAGTGAGGTCTATAAAGTGGAAAATTCGAAG +AAAATATTTCCAATATAAAACAAATGTTTGGCCGGGCGCGGTGGCTCACGCCTGTAATCC +TAGCACTTTGGGAGGCCAAGGCGGGTGGATCACCTGAAGTCAGGAGTTCGAGACCAGCCT +GGCCAACGTGGCGAAACCCCGTCTTTACTAAAAATACAAAAATTAGCCGGGCATGGTGGC +AGGTGCATATAATCCCAGCTACTCGGGAAGCTGAGACAGGAAAACTGCTTGAACCCAGGG +GGTGGAAGTTGCAGTGAACTGAGATCACACCACTTCACTCCATCTCAAAAAAATAAAACA +AATGTTCCCTTAATCAATAAAAAGACAGACAACCAGCCAGGCACGGTGGCTCACGCCTGT +AATCCCAACACTTTAGGAGGTCACCTGAGGTCAGGAGTTGGAAGACCAGCTTGGCCAACA +TGGTGAAACCCCATCTCTACTAAAAATACCAAAAATTAGCTGGGCGTAGTGGCACATGCC +TGTAATCCCAGCTACCCAGGAGGCTGAGGCAGGAGAATCGCTTGAACCCGGGAGGCGGAG +GCTGCAGTGAGCTGAGATTGCACCACCGCACTCCAGCCCAGGCGAGAGTGAGACTCGTCT +TTAAAAAAGACAAAAAAAAAACACCTCATAAGTTTAAGAATTTGTGTTGCACTGCATTAA +AAGCATTCTTGGGCCGCATGTGGCCTGCAAGCAGCGGGTTGGACAAGCTTGGCTTAAGCC +CAGGAAAGGCTGAGGCTGCAGTGAGCTGTGATTGTGGCATGCCCCTGCACTCCAACCTGG +GCAACATAATGAGATCCTGTCTCAAGAAACAGAAAAACATGCATGCTTCATACATTCAAA +ATATGCTGATGCACAACACTCAATTTAAACAATATCCAGGGAACACACTGAAGACAAAAA +CATTCAGGAATAAATTCTATCGTACTCCAATACTCTTACATAAAAAGCATAATCTGAAAC +ACAAGACAACCATGGCACTTCCATCTTACTTGTATTCAACCACCTTTCCCCTAACATTTC +CTCACTCTCACAGAAGCTTCCTCGGACTTGCCAGGAAAAGCTGACTAGAAAGATCAGCCA +CAGCGTCATTCCAGTTCAGTTGAGTTGTAATTTTTTTCTATGCACTCTTCCCCAACCCCA +GCAAAATTATGTATGCACAAAACCTTGCATATAGGGGGACTCTTGGCCCACGGATGCTAG +ACAAAAACATCTAGAAGAGAACTTCTTAAATCAAGATTTCAGAATTTGTACTAGAATACT +ACTGCTTTGTTTCTTAATCTCTGATTTCAAATAAAAGAAAATATGATCTCTATTCTTACT +GCTAGGGGGCAGGGGAGGGAACTGGGGCTTGACTACCCAGAATGAATTGTAGAAATGAAT +AAACAGATCAGAACTATAGTAACAATTATAAGTCCCTAATAAATTGCTTGCTTTAGCAAA +ATGACTAGTTGTTGGAATAGTGCATATCATGTGAGGATATCAGCCTTCCTTAGCAAAGAG +TTCAGTGCTTGCCATTTTTAAGTTAACCATTAGGCTATGACAACCAGTTCAAATGTGAAT +TTAAGTTTTAGAAGTAACGAAGCAAACACCTCTCTAGTGGCTATAATAATACAAAATTTA +TATACATATATCTACATGTATGAATTTTTACTAGACCTCAAATAAATGAACCATATGTTT +TCTTACCTTTGCACTAGTGATTGTACCAAATGGAGAAAACTCTTTCCGGAGACGTTCATC +ATCAATACCATCATCAAGATTTTTCACATAAAGATTAACACCCTAAAAAGAAGAAAAGAA +AACTATAGAAAAAGAAAACCATGGTGGTACCTAAGTACATCGGGTCTATTATTTTACCCC +ATATTTCTTCTCCTATTCCCCTCTCAAACCCTCCAGCTACCTGGAAGTAACTGAAATCAA +CGTAAAATAGGTTTCCTCATCCCTGTCTTATTTTGGTTGTTCAATTAAAAATGAACCTGG +TATCTGGTGATCCTATCTTGTTTCATCTGTTCAAATTTGCGCTTAAGTTCCGTCTGCCGT +TCCACCTTTTTCTGAGCTCGACCAACATAAATTTGTTTTCCATTGAGCTCCTTTCCGTTC +ATCTCATCCACAGCCTTCCCCCCAAAAAAAAAGAAAAAAAAAAAATCACAAAACTTTCAA +CTTACAGTTCATTTCCTTAACAGTTAAGACAAATTTGTTAAGTCACAAAAGCTAAAGACA +AACCCATCCCAAAATCTCAAGGTTTTGGGACAATATAGGTTACCAATTTATACTCTCAAA +CCTAATGCATAAAATGCAAATAACTGAAAATATAAGAACATGTCAAATAGCTATTAGTAT +GCACATAGACTTCAACACAAGAGCAACTCAACTTTGTACCCCCTTCTTCCTGCTGAATAC +AGACCACTTACTTTCTGTGCATCTTCATGCCTTTCAAAGCTTACAAATCCAAATCCTTTG +GATTTTCCACTTTCATCAGTCATTACTTTCACACTTAAGGCAGGCCCTAAAAAATTTTTT +TACATAAATCAAAGATATTCCATACAACATTCACGTTATACATTTCAAATTTCAACATAC +AAAGCCATGAAAAAAATTTCAAAGCTCCGTAACTTGACTCCTCCCTCCCAGCCTTCTATG +CCCCAGGTAGGTATACTTTTCCATTGAAAGACCTTTTATTATTAAGAAGGTAAACACCTT +CCCTCCCCTGAAGGATTCCTCCTTCCATTTAAGGAGGTACACTTTAAACGGCTGTAAAAA +GTTTTATTCTCAGCTCTAGCACAAAAGAGTTGCATTTTTTACCCAATAATTTGATTTTTT +CCCTTTTCTATAGAGACAGTATATCATTCCATTGCCCAGGCTGAAGTGTAGCAGCACAAT +GAATAAGCTCACTTTAACTCAACTCCTGGGCTCAAGTGATCCTCCTGCCTCAACTTACCA +AGTATCTGGGACTACTGGCCCACATACCACCATGCCTGGCTAATTTATTTTTTGTAGAGA +TAGGGTCTTGCTATGTTGCCCGGGCTAGTCTAAAACTTGTGGCTTCAAGTATCTTCCCTC +TTTGACCTCCCCAAGCGCTAGGGTTACAGGCATGAGCTATTGTGCTAAGACCAATTTGAT +TTTCTTTGTATCAATTAAGAAACAAGTATTTATTAAGCCTTGGCCTACCCGACTTTCAAC +AGGAGTGGAAGGAATACATAGTTGGACTCTTTGGTAAGACATAGGTAATACAGGAATTTG +AAAGACAGGGAAAAAAAATTCTTTTTAAAGACACAGGTGAACTACCTGGAAGAGGAAGCA +TTTATTTCTGAAGACATGTTTTCCCCTAACTCCCTCTAAAGTAGGAGAGACAGGTAACTG +AGGCGGGTGGTATCTCAGGCAAGTGGGGCAGAAAAGGTTAAAAATCACATTTGATTACAG +AAATTTAGAAGATGTATGGGCCAAGGCAGATTTTCTTCTGAATGTGCCTCTCTCCTGAGG +CCAAAGTCAAGAAAATATGACATATTCACATATTTGTGGTCAACTTATGCAGCATTACTC +ATACGGTAGGTAGTTAACATCAACTTTTACAAACAGCTTCTAATTATAAGACATTAAGAA +GCATGACAGTTGAAATATATAAAAGGCAGTAGCTAAATTTGGGGGTTGAGATGTAAACAT +GATGTCACTTTCTATGTTTTATATCATCTATCTTTGTGCAAAATGGTACTTTTTTGCTCT +AGTGGAGGGCTTGATGTGACATGCTAGCATGGCAGTAAGATATTAGATTTCCTGGCCAGG +CACAGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCGAGGTGGCTGGATCACTTG +AGGTCAGGAGTTGGAGACCAGCCTGGCCATCACGGTGAAACCCCGTCTCTAATAAAAATA +CAAAAATTAGCTGGGCATGGTGGCGCACACCTGTAATCCCAGCTACTCAAGGTAGAGATA +GGAGAACTGCTTGAACCCGGGAGGCGGAGGCTACAATGAGCCGAGATCACGTGACTGCAC +TCCAGCCCGGGTGACAGAGCAAGAGTCAAAAAAAAAAGTATTAGATTTCCTAATTCTTTA +TTATTTGACATATTAAAAAAAGCAAGACACCTCTAAGTTCAACACAAAATGCAAAGGGTG +GGGTCAAGCAAATCATCTGCACATGAACACTTAAAAGTTATTTTATCTGTTATACCCCTA +CCTAAACTAAGGCTGGTTTGTGCTTCATCAATTTCAAGTTTTATGAAGTTATTTTTAAAT +GCAGGAAATAAGTACTTTGAATCACTGGAAAATCTGAATTTTTGGTTTCATCGCTGAAAG +TCATTGTTTTAAACTGCTCAAACATGATGTTACTTAGACTGACCAGCTTTATTGTTCTAT +GAGACTGCATTCCACTGTAGGCTGGCTGTGTCAAATATATGCTTCTGATGACATGGGATC +TCTAATTACACACACACACACACACACACACACACACACACACATATATATCTCCAGCCT +CTTAATGTAGTAAAATATTTTAAAATCTGTTCTAATTACTTAGTCATACCTTACTGTGCT +AATCTAATGCTATTAACCTTTAACCTGGATAGAATTCTATTTATTTGCATTATACTACTT +TGTAGTGTAATAGATGGCCAGCAGCTTAATTCAAATAACCACAAATATTTTAAAGTACCA +TGTAAGTCTAATTTTATTGACTTTTTTAGTATAAAGTAATAGCTAAAATTAACACTGAGC +ACTAATTCAGAGCTTTGTGTGTAAAAATTTAATTAAGACACATTACCAAACTTGCCAAAG +AGATCCTTAAGGCGCTCATCATCCATGTCTTCTCCAAAATTCTTGATGTAAACATTGGTG +AATTCTTTTGCCCTAGCTCCAAGTTCAGCTTCTCGTTCTTTACGAGACTTAAATCGTCCA +ACAAATCTAATAAGATATACAAGGACTATAACATTAGATTCTATTTTATAAAGTTCAGAT +TAAGTAAGCCTGATGGTTGGTTTTGTTACTGTTAATGAGAATATTCAGAATCCCTAATAA +AAAGCACACTACAAAATAGAAATAGGGCCATAATTTAAGATATGACACCATGAAATATAT +GAATAAGCCTCTAACTACAATCACAAAAAAAAAACCACTTCTTTTAATACACACTTCTCT +TCTCTAGCTAACCTAGGGTTAAAGGGATCACTCCCATCAATACAAATGAGTGGAAGTGCA +TGTGTACCATGCCAATAAAAAGACCTCTATCAAATTAAAAAGCTTTCATCGTCATTTTAA +AGTGGCGCTTGCGCTTTCTTTGCCATCTCCTAGAATAAAAATTTAAACTTCCCAATCGTG +TACTCTAACACACAACAGCCTGACATAACTGCAGCATTTTCAACAAAATGACACTAAAAC +TTAATTTTTTCTGAATATAACAGTAGTAATTCAGAACAAGGATCACTGGGCTAGGCAGTG +GCTCACACCTGTAATCCCAGCACTTTGCAAGGCCAAGGTGGGATGATCACTGGAGGCCAG +GAATTCGAGTTCAGCCTAGCCAACATGGTGAAACTGTCTCTACTAAAGTACAAAAATTAG +TTGGGTGTGGTGGTGTACACCTGTAATCCCACCTACTTGGGAGGCTGAAGCACGACAATT +GCTAGAACCCGGGAGGCAGAGGTGGCAGTGAGTAGATTGCACCACTGCACTCCAGCCTGG +GCAAGAGAGCAAGACCATGTCTCAAAAATATAAAAAGAACAACGATCACTGAAGAAAAAA +AGGTAGCACATGTGTCATAGCATATTATAATACACAGCAAAGCAGAAGGAAAAACCATCT +TACATAATCTCACCCTAGTCATCTAAATTTCCTTATCTCTAACCCAGCTTTAGAATAAAA +AGTAAAATAAAAATAATTTCCTTATCTCTCCACAAAATATGGTTGGTCTTCGCTATGCTA +TTAGTTTCATAAATGTTCTCAAAGGGAGCGTATTTCATTGTGACCATCACTTTCTGCTTT +GTAAATAATGCTGCAACTTTTTTAAGAGACAAGGTCTTGCTATTCTGCCCTGGCTGGAGT +GTAATAGCTGTTCACAGGCACAATCACAACACACTACAGCCTTGGCTCAAGCATCCTGCC +TCAGCTTCCCAGTGGCTGGGAATAAAGGCACACTGCAGTAAAGCTGAAACTTTATGAAAG +ACACTTTGTGTATTTCTTCTTAGGACAGTTACAAATTTCCAAAAGAGTTATATCACTTTT +ACTCAAAACAGCAACATATCATTCTTTTCTGGATCCTGCCAGTGTTGGGCTTGCTTTTTT +TTCCTCCTAAAGCCCTGGTAACAGGCATTTGTGAGTATTTATTTATTTTTTTTAAAGACA +GTTTCAATCTTGTCGCCCAGACTGGAGTACAATGGCGAAATCTCGGTTCACTGCAACCTC +CGCCTCCCGGGTTTAAGTGATTCTCCTGCCTCAGCCTCCCGAGTAGCTAGGATTACAGGC +ATGCGCCACCATGCCCAGCTAATTTTGTATTTTTAGTAGAGACGGTTTCTCCATGTTGGT +CAGGCTGGTCTCAAACTCCCAACCTCAGGTGATCCGCCCACCTCGGCCTCCCAAAGTGCT +GGGATTTACAGGCATGAGCCACCGCGCCCGGACTTGTGAGTAATGTATGTCTCTCATTTT +ACAGTACATAAAAGCAAATTACTTTGAGTTTCCTCACCTATAAAATGGGTTAATTTAACC +AGTACCTCAAGAATTATGAATATTAGGTTTGTCTGAATTCCTGATTTTTCACTAATGCAC +TCATTTTGAAAAAGCTACATTTTTCTGTTTACTTATCTTCTGTTTTCCTTTTGGCATGAA +TGTTAATTATATTAAACCTGTTATTTGTATGTTACACTTACTGTGTAGAAAATTCAATTG +TAAAAATCAAGATTAGCTTATTAATTTTCACTCCAGTACAACTACATGAATTTTTGTTAT +TCATCTTTAAAATGTTTTTATTCTTTTATCTTATGTGCATCTAACTTCTCCCTGACAAAT +ATTAACTTAAAATGAATGGATTTGGAATTATTAAAAATAAGATTCAAAATATGATTAGCT +AGATATTTATAACTTACACTTTGCGATCATTTAGGAGCATTCCATTCATTTTTTCAATAG +CTCTTTCAGCTGCTTCCTGCGTCTCAAAGTGTACAAATCCATAGCCCTTGGAACCATTTT +CATCACAAACCACCTAGGGAAAAACATATACCCATTTTTCTTTATTTGCTATTGATTTAA +CATTTGTTCAGTGTTGAGAGACAATCTGTTAGCCATCTAACCTGGATATTTGTGAAATAA +AGATATCCATTACTGCACAGTTCCTATTTCAAGCACTAAACTAAATGTAGCTCAACAATG +TAAACATGTGTATCGGACATTTTTGGCTTACCTTACATGAAAGGATGTTACCAAAAGCAG +AAAATGTATCATACAGTGCTTTATTATCAATGGATTTGTCCAGATTTTTAATGAATATGT +TGCCTACTCCACTTTTGCGAAGTGATGGATCACGCTGAGACCACATGATGCGTACTGGCT +TGCCCTTTATAACATCAAAATTCATGGTGTCCAAAGCACGCTCCGCTGCAGGAAGGACAT +TTTCAGAGTCAATATTACTTCAAAATTTTTGCTGGCTACTTAAGATTATATAAACTATGG +TGACTGGAGTGGGAGGACACATGGTCTCACAGTTGAACGCTTCCTCTTTAAGCTTCAAGA +TGGCTAGACCTTTCAAGTATCACACACTAGTGTGGGACCTAAGTTGTATAAAGCAAAGAC +AAATACCAGAAGCCCCCGAAATTTCTCACATATAAAAGAATTCCATATTGCTAATAATTA +ATAAATTCTTGACGCAATCTCTCGCCTTAATTGCCATTAAATCTAAAGCACTTTTTTTCC +TAGTTATCAAAATCCAAATTCCTTCACATACAATCTGTTTAATAAGCAGTATAAAAGACA +TTACGCAACAGATTTATCTACAAGCTGGAAGTAGTTTATAGATTTAAATATTTTAACTTC +TTCCCAACTACTTGCTAAAATTGGTCATTTCATTGCTAATAACTAACAATATTATATGAA +AACTAGTCCATTTCCTAAAAAATGAAAGTTTCTTAATTATTGGGGGGAGGGAGGGTTTCA +GTGATTCATGGCACAACTTCCATTTAAGAAAATGAAAGGCTAGACCAAGATTTGAATCAT +GCTTTCAAAAGCTAATGTGAAGTTAGACATATTTGGTTTCATAATCACAGAATTTTAAAA +ACACCAGGTCTGCAATATTCAGAAATCACCATTAACGCTCTCTTGACACATACAATCAAT +TTCACTTTAGATCGCTGATTTTCTTAACAACTGATTTAGTTATTTCTGAATACTGCTAGA +AAATTTCAAAATCTACAATTAATTTCAGGATCTATAAAGGATTGAATTATGTATACCTGT +ACCATTAAAGGCTCTAAATGAAATAACACATCCTTAAATAAAAAGACTAGTCCCCGAAGA +GAGGGAAAACGGTCCCTTTTAAGCCCTGAAACAATTCCTACAAATTCCATGCCAATGTAA +ATTTAAAAGTTATTGACAGGATGAATTTTCCGGCCACCTCTTTTTTTATAAATGAAAGTT +CCAGTTTCTAGAATATAGTGATAATCAGCTGTTAGCTCATTATCAATTGACCACACCTAC +TCAGCTTCCCTAGTTTTTTTTTTTTTTTAGCTGACTTTGCTTGAGCTATTTTTCAATGAG +TCACCTCTTCCTATGAAATTGAAAACTGGTCACTTTCAGAAGCTATTCTGCCTATCAATG +TAGCAATAAGTTTTTAAAAAAGAACAAGAAATCCACTTAAGTAATTAATTGGATAGTAAA +TTGTACATACAGAAACTAGACAAATGGAAAACTGCCATATTCTTTTCAGTAGTTAGGGTA +CTGGTCTACTGGTACAGACTGATAATATATACTGTACACTGTAACCACGGCAACCTGAAG +TTCAACTCTTCGAATCCCAAGAAATGTAAAAATTGTTTTTTGGATTTAAAAACGTTAAGC +TGAGAAAGAGTAACACTTTCAAGTTTTCATTTTGTGGTCTCTAGAATTCATTCCCATGTT +TTCTCCACCAACTCTTAGGTTGTGATAACCTGCCCCAAAGTTATCTACCCCCATCTGACA +TGCATTGATACATCCTGCCTAAGGTTGACAAGAACTGTTATGAAGTGACATTTGGAGTTA +CTGCTTACAGAGCAAAAGGGCAGGAAACCTGCAGTGCAGTTTTACAACTTCTGGCTCTGT +GTCACTCAATATTCTGCTTCCAAAATCAGTATCAACTTTACACAGTGAAGAGCTGATCAG +TAACCTAAGTTCTACTGAATGAATGTTAATAGGAGCTTAAATTCCACCCTTAAGGCCTTT +TCTAATAAAAATGAATTCTTCATATTTCGATTATTTGACATGTATTCAAGTGGCCAGCCT +GTAGGGGGGGAAAAAGGCAAAATTGGGCCGTAAAATGGAATTAAGCTGACTTCTCAAAGC +CAATTGATCTAAAGACAAATCCTAGCAACTCAACAGACCACAGATATTATCTGTTTACAA +AATTGTGTTTCTGTTAACTGTTTAGCTTCAAAATAAAAGCACAAAGTTAGCTGCATTTCC +CCCATAAATTTCAAGCTCAATTTAATCTCCGTTATTTTGTACTCAGTCATTTCCCAAGAT +TTACAGGTATCATGGGCCACTTTTAAAAATAAAAGAGAAACTTGAACTTCTTGCATGCTA +CAGATAAGACTGGTCCAGTTGGAATTACACTAAAGTAACATTTTATAGCCAAAGTTGACT +ATTTTATAAAGAAAAGCCCCTCAAAACGACAGGAACTATTTCAGAAGGTAACATAATATA +CTCGAAAACCACCAGTACTGTGAATCTAAGATAAAATTTGACTAAAAATGGTCTAAGTTG +CCTGAGAAAACTGGCCTTCAAAGTGGTCGGCTGCCACATCCCCTCCTCCCACTCTGCCCT +TTTAATGTTAGAGAAATGCTTGATCTAGGGGAAACCCCAAATGCATGTCTCCGGTAAATT +CCATTCCTAGATCCATCAGTCACTGATGAGTTCTGGGAAGTGGACTCACAAGCCTGAGGA +CCACCACCACACCACACATCGCCACAGGAACTTTATCCTAAGGCCTGGTGGCTCCCCCAG +GCGACTGGGCCAGGAGCAGGAGCAGAAGCAGGCCTCGGGCCTGCGAGGTTACAGGGTTCA +ACACGTGGTATTTTTCGAGCACAGAACTGCACTTCCTCCCCAGGCTGGGGCGCCGGCAGG +AGCTCCGGGTGGTGGGAGCGCCTCCACCTCTTACCCACGGAAGGAGCTCAGCGTTCAACG +CCCCAGAATCCCGGGGCCACTGGCGGGAGCGCCGCGGAGGAACCGAATCTCACCCACCCT +CCCGGCGCGTCATCACCCTAAAGTTTGAGAGCGTCTGAGGCCGAGAAAATGGTCGCAAAG +GAGGAAGTAGCCGGGCGTGTGGCTGCCGGCAGCGCGGGTCCCCGCCGGCTCGGGAAACGC +GGCTCCAGGGACCCCGGCGCCTTCCCGCCGGCCGTCGCGGGGTGACATGCCCTCCCGCCC +CCCTCCCCGGGCCCGCCGGCCTACCCCGCCCGCCGCCGCCGCCCGAGCCTCATGGCCGCC +CGCCCGCCCGGCCGACCGCGGAGCCCGGCGCTCACCGTCCGCCGGCTGCTGGAAGTTCAC +ATACGCGTAGCCCAAGGAGCGGCGGGTGATCATGTCCCTGCAGACCCGGATGGAGAGGAT +GGGCCCGGCCGGGCTGAACTTCTCGTAGAGCATCGCCTCGGTCACGTCGGGGTGGAGGTC +CCCCACGTAGAGCGAGGCCATGGGGTAGCTGGGGGCACTGGGGTTCATCTCGGCACGGCT +GCCCGCAGGGCCACAGGCCGCGACCTTTCCGTGAGAGGAGGAGAGCGAGTGCCGGGGCTG +GGGGCCGGAGCCGGGGGGAGGGGAGCGGGGAGCAAGCGCAGAGGGACAAAAATCAACCGG +AATTGAAAACTACTCAACGGCCGCAGAACGGGGTCGATCCACTGCCGCTGGCTGCCGGCT +GCCGGCGGGGAGCGAGGGTGGCGGTGTCGGGTCCGGGCAGCGGGAAGGCCTCGGTCTCTT +GGTTCCTTCTTGGAGCTGCTGCGGGGCCGCGGGCGGGCGGGTCGGTCTCGGCTGCTTCAC +CGGGTTATTTTATAAAAGAGGAAGAAAAAAAATAAAAGTCTCCGGCGGGGGAGACGCGGA +TTTTTTGTAAATTTTTTTGGGGTTTTTTAAAAGATTTTTTTAGATTTTTTTTGGATTTTT +TAATAATAAATGTGTGTTCCGAGCCCGGAGCACACACTCCGCACTCTCAGCACTAACCGC +CGGGGAGAAGGGGAAGCACCGCCTCCTGCACCCTCTACTTATACCCCGCGCCGCACTCGC +CCCGCCCCCGCGCGTCTGACGCCAGGGCCCCTACGCGAGCGTCAGCGCCGGAGTAGGAGG +AGACGCGGAGGCCAGGGGGAGGAGGGAAGAGAAAACAGGAGGAAAGAGCAGAGAGGAAGG +GAGAGGTGGCGGCGGTGGAGGCTGCGGTGTGGGGGTGGGGCTCGGGCGAAGGGGCGGGGC +TTTTGCGCAGGCGCCGCGGCCGGGGAAGCGGAGCCCGCGCTGCGTCGCGTCCGTGGGGGT +GGGGAGGACGGCTCGCGGGCGGTCCTCGGGGGTGTTGGCTGAGGCGTCCCCGCCTTCCGC +CCCGCCCGCCCCTGCCTCCACCAGGAGGAGCGTTAACCCGTCACCGCGGCGGTGGGCGGT +GCAAAGGGCTTCCGGGTTCCTCCGCGCTAACCACCCCCCACGTGCGCGGCCGCCTGTGGC +CTCTTCCCGCTGCGGCCGGCCCGGCTCCTCTAGCCCCAGCTCCGGGGGACGCCGGGCACG +GGTGAGCGGGCGTGGTCCCCTCCGGGCCCGGTTTCCGAAACGTGCGTAGATGGAGCCAGC +GTGGCCCCCTGCTCTCTCCTACCCGGACCGCACTACGAGTCCCAGCCGGCACCGCCGCCA +CGCGCGTCGGCCGCAGAAGCGGTGCCTGCTGGGAGCTGGAGTCCCCAACGGCCGCGGCGC +TCGCTGACACCAACTGGCTGCGCGGGTCCTGGCCGCCCGCTCCGGGACCCCCCAACCGTC +CTGCGCGCTGGACCCCGGCACCGCTGGAGCTCCCGGCGCGGGGTTGGGGGGCAG diff --git a/test/csq/ENST00000520868/ENST00000520868.fa.fai b/test/csq/ENST00000520868/ENST00000520868.fa.fai new file mode 100644 index 0000000..a3e56d6 --- /dev/null +++ b/test/csq/ENST00000520868/ENST00000520868.fa.fai @@ -0,0 +1 @@ +8 37194 25 60 61 diff --git a/test/csq/ENST00000520868/ENST00000520868.gff b/test/csq/ENST00000520868/ENST00000520868.gff new file mode 100644 index 0000000..855c36a --- /dev/null +++ b/test/csq/ENST00000520868/ENST00000520868.gff @@ -0,0 +1,15 @@ +8 ensembl_havana gene 101 37094 . - . ID=gene:ENSG00000070756;Name=PABPC1;biotype=protein_coding;description=poly(A) binding protein%2C cytoplasmic 1 [Source:HGNC Symbol%3BAcc:8554];gene_id=ENSG00000070756;logic_name=ensembl_havana_gene;version=9 +8 ensembl_havana transcript 17201 21216 . - . ID=transcript:ENST00000520868;Parent=gene:ENSG00000070756;Name=PABPC1-006;biotype=protein_coding;havana_transcript=OTTHUMT00000380216;havana_version=1;transcript_id=ENST00000520868;version=1 +8 havana exon 17201 17644 . - . Parent=transcript:ENST00000520868;Name=ENSE00001378950;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001378950;rank=6;version=1 +8 havana three_prime_UTR 17201 17644 . - . Parent=transcript:ENST00000520868 +8 havana three_prime_UTR 18565 18582 . - . Parent=transcript:ENST00000520868 +8 havana exon 18565 18675 . - . Parent=transcript:ENST00000520868;Name=ENSE00002101657;constitutive=0;ensembl_end_phase=-1;ensembl_phase=0;exon_id=ENSE00002101657;rank=5;version=1 +8 havana CDS 18583 18675 . - 0 ID=CDS:ENSP00000428021;Parent=transcript:ENST00000520868;protein_id=ENSP00000428021 +8 havana exon 19211 19341 . - . Parent=transcript:ENST00000520868;Name=ENSE00003465118;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00003465118;rank=4;version=1 +8 havana CDS 19211 19341 . - 2 ID=CDS:ENSP00000428021;Parent=transcript:ENST00000520868;protein_id=ENSP00000428021 +8 havana exon 19874 19958 . - . Parent=transcript:ENST00000520868;Name=ENSE00003509544;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00003509544;rank=3;version=1 +8 havana CDS 19874 19958 . - 0 ID=CDS:ENSP00000428021;Parent=transcript:ENST00000520868;protein_id=ENSP00000428021 +8 havana exon 20936 21090 . - . Parent=transcript:ENST00000520868;Name=ENSE00003689366;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00003689366;rank=2;version=1 +8 havana CDS 20936 21090 . - 2 ID=CDS:ENSP00000428021;Parent=transcript:ENST00000520868;protein_id=ENSP00000428021 +8 havana exon 21172 21216 . - . Parent=transcript:ENST00000520868;Name=ENSE00002114920;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00002114920;rank=1;version=1 +8 havana CDS 21172 21216 . - 2 ID=CDS:ENSP00000428021;Parent=transcript:ENST00000520868;protein_id=ENSP00000428021 diff --git a/test/csq/ENST00000520868/ascii-art.txt b/test/csq/ENST00000520868/ascii-art.txt new file mode 100644 index 0000000..e75bdab --- /dev/null +++ b/test/csq/ENST00000520868/ascii-art.txt @@ -0,0 +1,6 @@ + 21090 21171 21216 +eeeee eeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeee +GTTAGCTAAAAAATAAGAACATTTTGTATTTTTATCTTGCTCTTTCAAATTGGTGATCAATTTTTAAAGGAAGGATTAAGACTCACCAACACGCTGTGTTGACATGACTCGTGGAACCTGTGAAGAAGCTG +GTTAG---------------------------------------------------------------------------------CAACACGCTGTGTTGACATGACTCGTGGAACCTGTGAAGAAGCTG + ssssssss + diff --git a/test/csq/ENST00000520868/long-deletion.txt b/test/csq/ENST00000520868/long-deletion.txt new file mode 100644 index 0000000..102a7c8 --- /dev/null +++ b/test/csq/ENST00000520868/long-deletion.txt @@ -0,0 +1,3 @@ +21090 GCTAAAAAATAAGAACATTTTGTATTTTTATCTTGCTCTTTCAAATTGGTGATCAATTTTTAAAGGAAGGATTAAGACTCAC G splice_acceptor&splice_donor|PABPC1|ENST00000520868|protein_coding +21090 GCTAAAAAATAAGAACATTTTGTATTTTTATCTTGCTCTTTCAAATTGGTGATCAATTTTTAAAGGAAGGATTAAGACTCAC G splice_acceptor&splice_donor|PABPC1|ENST00000520868|protein_coding + diff --git a/test/csq/ENST00000520868/long-deletion.vcf b/test/csq/ENST00000520868/long-deletion.vcf new file mode 100644 index 0000000..e1fece6 --- /dev/null +++ b/test/csq/ENST00000520868/long-deletion.vcf @@ -0,0 +1,7 @@ +##fileformat=VCFv4.2 +##contig= +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO +8 21090 . GCTAAAAAATAAGAACATTTTGTATTTTTATCTTGCTCTTTCAAATTGGTGATCAATTTTTAAAGGAAGGATTAAGACTCAC G . . EXP=splice_acceptor&splice_donor|PABPC1|ENST00000520868|protein_coding;type=ENST00000520868:101719033-GCTAAAAAATAAGAACATTTTGTATTTTTATCTTGCTCTTTCAAATTGGTGATCAATTTTTAAAGGAAGGATTAAGACTCAC-G diff --git a/test/csq/ENST00000528237/ENST00000528237.fa b/test/csq/ENST00000528237/ENST00000528237.fa new file mode 100644 index 0000000..ccb6385 --- /dev/null +++ b/test/csq/ENST00000528237/ENST00000528237.fa @@ -0,0 +1,993 @@ +>1 1:47023070-47082535 +ACCACCAAATAGGCCACACATAGAATTTCAGTTTTATTAAAATAAGCACAATGTATAAAA +GCACCGTGGTGTTGTATAAACGTCTGCCTGACAAATGCAAATCTATTTTCTTTATGTAAC +TCAATAGTTCCACTTATCTGAATGGCTGTACCTTCATGCACACGGGCAGCAGGCACTGCA +TTGCTCAAACAGGGAAGTGAGGCTTCACCCTAGTGTGGCTTCACCTTAGGCACAGAGCAC +TATCTAACTGCCCAGATCTGTGCCACCCACACAAGACCTGGGGACACAGCAGCAGACACC +GATGCTGTCTCTAAGTTCATCACAGGAACAGCTTAAAATCAGAATAATAGGGAACTGCTG +ATTAAAACCCAAGTGCATGGACATTCTAGAAAGAAGAGCAAGCCGTTCCACTCTCTGGGA +AGTTCATGGGCTTGCAGTGGGAGTTTAAGGTATCATCTTTGCTGGAACAGCATGGTTAAA +AACACCAAACTTTTTTTTTAAAAAAACGATACTACTGACTTTAGCAGCAATCACAAACAA +AGGGGATGATAAACGAGGGATACATTTCAGTCACAGCAAAGAAAGATTATGTGCTTTTCC +GTGCTGCAGACCGGAAGACTGATTTGATTTCCTGAATGAGGAAGGCTCCTTGCCCTTCCC +TGAATTGAGGGGATGGCTTTGCTCAGCCAAGGGAGAAGACGGGCAAAGAGGACATCCGGA +GGACAGAGGAAGGTGGAAGGACCGCCAGAGGAGGGTGACAGAGAAGAGAGGGAAGAGGCA +CGTGTCGGCAGCCTCTGTCAACTGATGCTTCTTGCTTCTCCCTGCAGGCTGCAGCCCCAG +CCGCCACAGCTACAGCGGTGAGAGCAGGCTGGATCCCAGATCTGCAGGCGGGTGAGCAGG +TGGAGCCCAGTGAAGAGATGTTCCTGCTGCAGGCAATTATGCAAAGTGAGAAGTGATTGC +TTTCCTTTTCAAAGACAACCCCTTTGGAAAAAGCTTTTTCCTCCAGGACCCTAGGGAAAT +GGGGGTTGATGGGAACCTCAGGGCCTTCGTAGATGAAAAAGCCTGAATGGAGCCACAGAG +CAGAGGCTGCTGCCTGCTCAGCAGACTTTAGCCACACAGGTTTCCAGGGGACAATGCCTG +GCCAGGCCTAGGGCCTATAAGGTGTGACTGGAGCATTTCAGAGTGCTGTGGGCGGGCTCC +TGTCTTCACCACGGCCTGCCTGGGCCAGGGCCCGTCTCCGGGCCAGGCGTGACTTGCAGG +GAGGGGAAAGCTTCATGGAGCAGAGGCCATCAGCTAGTGCCTCTGGCTCCTCTGCTAGTT +CGTTCTCTTCGTGCTGAGATAGCTGGCGGTTAAGGGCGATGGCCTCAGCTGCGAAGAGCG +TCAGGTCCATTGTGCTGCTGTTCCTGCAGGGCCAGGGGAAAGCACAGAAAAGAGGGTCAG +GACTCTAGGGTCAGCCAGGCCAGCTCCGGGACACTCCCACTTGCTGCTGTGGCTCTACGC +TCCCACCAGATTTCCCAGAGCTGGGACGGGCTGCTCTCTCCAAAGTAGTTCTTGCCTAGG +TTTGGAATCTTTCTTGACTGAGGGATTTTAATTTGAGCCCCAAGTACCATCCCTGGACTT +GATGGTAGGGGCAAGCTCCCCCTTCTCCTCAGAGCACCCTCCTCTGAGCTCCCACAACTC +TACATACAGGTCTACCAGAGGCAGAGACTGGGCACATGAAACACACCTGTCCCTCCCTCT +CCCAGCCTGCGTGGGGAAAAAGCTCCCAGAGCAAGGCCTGCGCCGCTTATGCCACGTCCC +CAGCACCTAGCTCAGGGCTAGCGTGGACAGGCACTTTGGGTTTGCAGAATAAATCTTCTA +AGGCGGATCTGAGGTTTGGCATCTAAAGGCATCTGGAGGCTGCTCTAGAGAGTCAGGTAG +GAACCCAAATTGGGCAATAGCAACTGGGTCACACGAATTGCGATTATGGAGGTGTATGAC +TTCCTTGTGTAGCTCCTAAAAGCTGGCCATGAGGCTGGTGCCAAAAAGGTTTCCCACACT +GCTTAGCCCTGGCTCTTTGGGAACAGGGCAGTCCAGCTGTAAAAGGGCTCCAGAGTCAAA +CAGCCCAGGGCTGCTGTGTGGCCTTAAGCAAGTTAACTTGATTGCCACTCCTCACCTCTC +TCATCTAGAACACCTCTCTTAAATTCATCGTGAAGATTATGGATATAATTATATCCAGCC +CTTAGCACCACGTCTGACATGTGGTAAGGACTTACTATTTTTTTTGAGACAGATGCTTGC +TCTGTTGCCCAGGATGGAGTGCAGTGGCGTGATCGCAGCTCACTGCAACCTCCGTCTGCT +GGATTCAAGCGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGCATTACAGCACCTGCCAC +CATGCCTGGCCATGGTAAGGACTTAATCCTGGTGGCCACTATTATCACTGTCCGTCTAGT +ACCGTACGTGCCCCTCACTTCTGCTCCTTTCATTAAATACAAGGGCAGAGGGAAGCCTTG +TGTGAATAACCCATGGGTAAGGTCTGTCTTTGGGCTGTAAGTTACAGTTCAATGGGCAAA +ACAGGTTTTTTTTCCTGCCAACAGTGCTAGGAGGGGCCTTAAGGTGCTGGAGGGCAGAGG +ATCCAATCTAGGTGAAGGAAGGGAAGGGTGGGAGATAGATCCAGAGTAGAGGAAAAGAGA +GTGAGGAGGGGAAATGGGCAGGGAGCCCCTTTGGAGAAAGCTACCTGAGCCTAGAGATGG +GCTCCCCCGGCCCCCACCCCCATGGTGGCTGAGAGCTTGAGGAAGAGCATGGCGTGGGGG +TGGTCAGAGCATTTACCTCTGGAGGACTTGCGGCGTGGGGAGTCCCTTTTCTGGAGCTTG +CTAGAATGGGAAGGACAGATGTGTAGGTAAAGCACTGCTCCCTCCTTTCAAGAACTGCCC +CACCCAAGCCAGCAGTGGGTAGGTTACTATAGGCTGCTGGCGCAGCACAGGGAAATGGCT +ATGCTTGCTTGCAGGGTCAGGCCTTCCAAGCAGAGAGCAAGAAAGGTACAATCTGCAGCC +GCAGCCCCCAACATAGCTGCTTCTGCATGGAGAGCCCCTCTTTCCCTTTGCCTGGCAAAG +TCCTAATCATCCCCCAGGACCCAGCTCAAGGGTCACTTCCCCTGTGACGCACATTTCCCC +TTCCCTGCCACCTTCCTGCCTCAGTCTCAGGCCCGGGATGGGGAGTGGGGTCTTGCTCCC +TTTGTGCCCCTAGCACTTTTCAGAAGCCTTTATCATGCTGTAACTTATCCCCTTGTCTAC +TTCTCTCCACTAGAGCACAGAGACAGGGACTGGGTCTCACTTGTCCCTCTGGCATGTGGC +AGGTGCTCACTTATGGGTCTGGGAATGAGCCAGTTAGACACTCAAACTGGGTCCCCATCT +GCAACATAGGATGGCAATGCTTGCCTCCTTCCACTGGTAGGGTCACTGAGGCTGGCCAGA +GCCTGGCACACCAAGGAGACCAGAAAGTCATGGGAGCATCTGGCAGACCCCTTGGAGGGC +AGAGGTCAGGTATTGTGAGTAGCCAAGGAGGATTTTTAAAAATGTTTTCTAGTGAAGACA +TGAATTCTAAGCTTAGGGAAAAAATACGATCATTTGCCTTTCAGGCCAGCTGTACCCAGA +CTCCCAGACCATGAGGAGAACCTATGTGCCCCAACTCGGCCACACAACAATCAGCGCAGC +ACGGCCTTGCTCACTTCTGGGTGTCCTCAGCTAATGATGCTTCTATATAAGAGGAGGATG +CTACAGACTTCAAATGACAATAGGATGCTTGCGGGGCTGGGTGCATGTACCAAATCCCCA +GAGGACTCTGTTGGGGCTTAGTCTGTGGCCAAGTTTACAGCCAACTCTATGGCCTATAAG +GGGCTCAGTCTGGGGTAACAGGAGGAGTCGATTCACTCTACACACTCAGGGATAGACGCT +GTCCTCTTCAGCTGCACCAGCCACAAGGCTGGTGCTCAGCACTTGCTGGCATGACAGCTT +CCTTGTGGCCATGCCACAGGCCTGAAGTGGTGGAAAACACCCCTCCCTGGAGTCACTCAC +CCCCTGCACCCATGGGTGCTGCAGAACTTGGGCGGCGCTAAGTCTCTGCTTTGCATCTCG +CACCAGGAGCTTGGAGATGAGGTCTTTGGCTTCACTGGAGATGTGTGCCCAGTCCTTGTC +AGGAAACTCATACTTGCCTTCCTGGATGCTTTCAAACAGCTTGTTCTAGGTACAAAAGAT +TCCTCCTGAGGCCACACTGCCAGGGATGGGCAGGATGTGCCTGTCATTGTTTTGATCAAC +CGGCTTCAATTGATCTCAGCTGTAGCTGCAGCTCATGGCTTGGGGATGCCACAGACTGGG +GCCTCTTCCCAGACTCACCCCGCACTGTCCCCTAGATGATCAAACTATATAGAATGCCCT +TGGCAGGCCAGGATGGCTATGCCCTTGGTGGGCTGGATGGGTGATGAGTGGAGATCACCC +ATAGAACAAAGCCCAAATTCCTTGGCTCTTCCTAGAGGACTCTCTGTGAACCTCTCAGGC +CTCATCTCCCACTACCACCGACCTACTACTCCACTCTTCCTTCCTAGACACTCCAGCTAT +TTCATGTGCCCACATCTATGCCCGTGCTGTTCCTTCTACTTGTGATTCTTGTCCCTCTTC +CGCAGGGCAGGATGCACCCTTTAAGAGTCAGTTCAGGGCTGGGCGCGGTGGCTCACGCCT +GTAATCCCAGCACTTTGGGAGGCCGAGGCGGGAGGATCACAAGGTCAGGAGATTGAGACC +ATCCTGGCTAACACGATGAAACCCCGTCTCTACTGAAAATATAAAAAATTAGCCAGACGT +GGTGGCCGGCGCCTGTAGTCCCAGCTACTTGGGAGGCCTAAGGCAGGAGAATCGCTTGAA +CCCAGGAGGCAGAGGTTGCAGTGAGTCGAGATCGTGCCATTGCACTCCAGCCTGGGCGAC +AGAGAGAGACTCCATCTCAAAAAAAAAAAAAAAAAAAAAAAAAGAGTCAGTTCAGGCATG +ATCTTCTAACAATCCTGCCCTGAACTCCCAGCTGGGCGGAGTGTCTGATTATCTCTATTT +TACCTTGTGGCCACCGTGACAGGAGCGGGAGAGGGCACTATGAGCCCCCATCCCGATCAG +GAACGCTCTCCCAGCCCAGTCCTGCTTGGCATCCCCCAACCACACTGACCCCTAGCAGGG +TCTACGCAGTGCTCCCTGGGGCCGCACTCACCTGGCACACCCTGCAGACCTCGCCCCGGT +CCCAGCCACAGTCGGCCCCGCAGTGACCCACGAAGGGTGGGTAGCCACTCAGCATGATGT +AGAGGACCACGCCCAGGCTCCACAGGTCACAGCGCTTGTCGTAGAATGTGGCCTGGTCCG +TGAAGACCTCCACTACCTCAGGGGCCATGTATTCTGCAGAGCCACACTGTGGGGGCCAGG +GTTGGGGGAGGGGGAGATGGCAGAGAACAGAGAGGCTTAGTTACAGCAGAGGGGATGGCA +GAGAGCAGACTGTGATGGGACTGGAGCAGGAGGCTGGAAGGATGAGATACAGATCAGGAA +GGCCAGCCAGTGAGCCGCCTGATGCCACCAAGGCATCTGCAGACTGAGCTCCATCATTTT +CCATCATCCAGAGGAGCAGTTCAGGTCACCTTATCCTTCCAGTTCCTCCTCCAGTAGGCA +AAGACCCTTGGCCAAGAAGTTCCAGGAATCTCCCCCTGCTTCAGCTTCCTATAAACAGAT +ATTTCATGTACAGGTACTTAAATGCACCAAGAATGTGGCTCTGGAAGGAGATCCAGTTCC +ACACAGCAAGATTTCTTAAAGTGAATCCTGTCGTGCTCCCCTGCTAGCTCAGAGCAGGAA +GTGTAACAATTAAGAGACCGTCAAAGCTACAAAGCTCTTAGAACAAATCCAACCTTCCCA +CCCCTCCCATTTATAGATGGCAAGGGCAAGGCCAAGAACGGGACAGGGATCTGTTTGAGC +ACATCAATGGCAGCCCTAGGACCAGAATCCAATATTCCTTTCTCTCACCCTTGTGTAGAA +AGCGGCTGATAGGAATAAAACACGTTCTTTTTGCTCCACTCTTCATTATTTCAGGCTCAC +CAAGAAACAACCACCTCCCGCCTCCACACACCCTGCAAAACTAATTTGACTGAAAGATGG +TAAGTGTTCTCAAGAGAGGATATTTTCTTTGTTATTGTCAATTAGAATTAATGACTTTGA +AAACAAGGTAGTCCAGTGTGTTAGAAGCTAAGAAAGAAACATTCCTGATAATGTTGTTTA +GAATAAGATACAACACAGGCATATTAAATATGCCCTTAAAGGGCATGTCTTAAAAGGGTT +ATTAGGGGCCAGGCGTGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCG +GGTGGTTCACAAGGTCAGGAGATCGAGACCATCCTGGCTAACATGGTGAAACCCCGTCTC +TACTAAAAATACAAAAAATTAGCCAGGCGTGGTGGCGGGCGCCTGTAGTCCCAGCTACTC +GGGAGGCTGAGGCAGGAGGATGGCATGAACCCAGGAGGCAGAGCTTGCAGTGAGCCGAGA +TCACGCCACTGCATTCCAGCCTGGGCAACAGAGCAAGACTCTGTCTCAAAAAAAAAAAAA +AAAAAAAAGGGTTATTAGGAAAATTTACTTGTGAAGCATACAAATCTCAAAAGAATCATA +ATTATACTCTATTAGTTATACAAGAGATGTTTTAGGAAGAAGTAGCTCCAAGCAGCACCA +TCTGGTCATGAAATGTGAAATCAGAGAAGCAAACAGGCTAACTTGGCCAAGCGATCCCAT +GTGCATATAGCCTGAGACCTCACAGTTCCCACCACAGAGAGACTATCCTGTCCAGTCAGG +GAGAACAGCTCTCCATCCCCCATTACAAGGGGGCTGCGCTGTGCCTTCAGCAGTGGGAAT +AGGACTTACAGAACTACCCAAATGCTCATATGCAAAAGGGCTGGCCTGGGAGTAGGGTCC +ATTTTCACCTGGGTCAGGAGTCAGGGCTCAGCCTGTGTTTTTTTTATTGTTTTTTTTTTT +TTTTTTTTTTTTTTTTGAGACGGAGTTTTGCTCTTGTTGCCCAGGCTGGAGTGCAATGGT +GCTATCTCGGCTCACCGCAACCTCCACCCCTCGGGTTCAAGCGATTCTCCTGCCTCAGCC +TCCCAAGTAGCTGGGATTACAGGTGCGCGCCACCATGCCTGGCTAATTTTGTATTTTCAG +TACAATGGGGTTTCTCCATGTTGGTCAGGCTGGTCTCAAACTCCTGACCTCAGGTGATCT +GCCTGCCTCAACCTCCTAAAGTGCTAGGATTACAGGCATGAGCCATTGCAAACGGCCAGC +CTGTGCTTATAGATATAATTTGTCTCTTCATCAGCAGAGAGGACCCAACCCAACTAACAG +TCCAAGTGTCAGTTTCGTTAGCAACTAAGGGGTCAGGGGAGGCTTGAGAGCCACGAACAC +AGAGCAGCAAGCAAAATGATCACTCAGGCAGCAGGAAGATAGGTCCACTTGGTTTTCCAT +CCTTAACCCTCTGTTCTGGACCTCCCAGCTCTGGATCAGGGAAACACTCCAAATACTTAG +GAGCCCAGAGGAAGCATACGTACTGGGGTGGTCAGCTCTGGTGTGGTTATGGGGGTACAG +GAGTTGTTCAGTTTCATCCCACTGCCCAAGTCAAAGTCACAGATTTTCACTGGAGACACC +TGAAAAGGAAAACAGAAGACAGGGTCACAGATATAAGAAACTACGGGGCAAGAGGAGCCA +GGCATGGCTGTACGGGTGCATGGCTCCGTGGCTGTCACACCGCAGCTGGTTTTGTCAGGT +CATGTTTGCTCTCCGGAGGTTAACAAGAAGTCCCCTGAGGATTTCTTCCCAAGTGTCTTA +TTCCCTGAGCTCTCTTATTTCCCATCTAAGGGAAAAATGGGTGGACTATTTGGTGTCAGA +TTATTGTGAACTCAGACTAAAGGAAGTATGGAACTCTTGCTGGCAAATGATGGTACAGGT +TGCAGCACAGCAGCTAGGGAAGTTACTGTGTACTCCTGAGAGACAGACTTCTTGCAGCCC +ATTCAGTGGAGTGTAAAGGAGCTTGCAGTAAAACCTCTGACCGCCTCAGGTGGCTTAGGG +TGACCAACTTGTCTTGGGTGGCTTGCTTGGGACTTGATCAGTTTAAACACGGAAACTCCT +GCGTTCCAGGAAACCCCTCAAGCCTGGGAAAACTGGGATGGTTGGTCACCGTAGGTGGCA +TCAACACAGTAACCAAGTCCACCAGAACTGGATGCTGTGCCTGAGACCACAGACAGGTGC +CTCATCTCTGGAGCCAACCAGGAAGGCAGTTTGGGTGCACACATGAGAATGGATGAGAAT +GGCCTACATGGCATGTAAGCAGCACAGCGAGTGAACTAAATGCTGGTTCTCTGAGACCCA +TGTCCTTGCCGGGAAGCCTGGGCAAGTCCCTCGACTTCTTTCTCCCCTTCCTTCCTCCCT +CCCCTTTTCTCTATTTTTTCTTCTTTTCTTTTTCCTTTAGCCTCTTATTAGTGGTAAAAT +ATAAAGCATAAAATATGAGATTTTAGCCATTTTTAAGTAGACAGTTTAGTGGTATTAATT +AAGTACATTCACAGGGTTGTGCAACCATCACCACGATCTGTTTCTAAAACTTTTCCATCA +CTCCAAACAGAAACTCTATACGCATTAAGCAATAACTCCCATTCTTTCTTCCCCTAGCCC +TGGGTAACTTCCAATCTGACTTTATTAATTAAGACTTTCTGTCTTTATTAATTTGCCCAT +TCCAGATATTTCATATAAGTAGATTTACACAATATTTGTCCTGTTATGTTTGGCTTATTT +CACTTAGCATAATGTTTTCAAGGTTCATTCATGTTGCAGCATGTATCAAAACCTCATTCC +ATTTTATGGCTGACTAGTATTCCATTGAATGTATGTACCACATTTTGTTTATCTGTTCAG +CTGCTGATGACCACTTGAGTTGTCTCTACCTTTTTGGCTGTTGTGAACAATGCTGTAATG +AATACTGCTATACAAGTATCTGTTTTCAATTGTTTTGGGTAATACCTAGGAGTGGAATTG +CTGGGTCATATGGTAATTCTGTGTTTAGCCTTTGAGGAACCGCCAAACTTTTCCACAGAA +GCTGCACCATTATATAATCTCACCAGCAATGTATGAGGGTTACGATTTCTCCATAACCGT +AACAACACTTACTATTTTCCATTTTTTAAATTACAGCCTACCTAGTAGTATGTGGTGGTA +TCTCATTGTGGTTTTGACTTGCATTTCCCTAATGACTAAGGATGTTGAGCATCTTTTCAT +GTACTTGTTGGACATTTGTGTACCTTATTTGGAGAAATGTCTGTTCAAGTCCCGTGTCCA +TTTTTAAATTGGTTTGTCTTTTTGTTGTAGAGTTTTAGGAATCCTTTATATATTTTGGAT +ATTAAACCTTGACCAGATATATGATCTGCAAATATTTTCTCACATTCTGTAGATTGTCTT +TTCACTTTCTTGATAGATAATGTCCTTTGAAACTTAACCTCTCTTTTTCTTAAGAGACAG +GGGTCTCACTATATCACCCAGGCTGGCCTCAAACTCCAGGCTCAAGCAATTCTCCTACCT +CAGCCTCCTGAGTAGCTGGGACTACAGGCATGCAACCGCTGTGACCAGCTAATTTTTAAA +TTTTTTGTGGAGATGGGGTCTCGCTTTGTTGCCCAGGCTGTTCTTAAGCTCCTGGCCTCA +AGGGATCCTCCTGCCTCAGCCTCCCGAAGTGTTGGGATTATAGGCGTGAGCCACTGCCTG +GTCCCAATTATTCCTCTCTTTCGCCTTGCCTTTCCTCACGTTCTTGTTATGAGACAGAAT +CTCTGCTGCCCAGGCTGGAGTGCAGTGGTGCAATCATGGCTCACTGGCTATACATGTTTC +CTAACTTGAGTTTCAGTTTCCTCGTCCATAAAATGAAGGTAATAATAGTATCTACCTCAT +GATATTTCATAAACACTAAATAAATATAAGTGCCTGGCACAATGTAAGCACTCAAGAAGT +GTTCACTGTAATTATTAGTAGTAATCATCATAATAATGATAAATTATAAAGGTCTACGAC +AGAATCAGTGACAGAAGTCACAAGATCTTATTTGAGCGAATCCATTATTATTCCCCATAA +AAGAGTTGTGAGTAGCAGACTGACTCATTCATTCAAGGCCACCCCTTATTTATGAGCCGC +GGCTTCATCCAGACCACAATATATATGCTCTTGAATACACACATGTATATACACGCAGAG +CTGTGAACGTGGGCCCCAACACCACCAGTGCCTAAATCTCTCCTAATAAACACAGAATTT +GTCAAATTCATACACTTCCGTTTACTTAAAGAGATCTGCTTCACATAAGATTAAGTTGTT +TGGCTGGGCATGGTGGCTCACGTTTGCAATCCCAGTACTTTGGAAAGCCAAGGCAGGTGG +ACTGCTTGAGCTCAGGAGTTCGAGACCAGCCTGGCTAACATGGTGAAACCCCTGTCTCTA +CTAAAAATACAAAAATTAGCCAGGTGTGGTGGCACATGCCTGTTGTCTCAGCTACTTGGG +GGGCTGAGGTGGGAGAACCACTTGAGCCTGGGAAGTCGAGGCTGCAGTGAGCTGTGATCA +TGCCACTGCATTCCAGCTTGGGTGGCAAAGTGAGACCCCGTCTCAAAAAAAAAAAAAAAG +TATTTACGACTTCCATCAACTGATATAAAGATAGATGCATTGGACTAGAAAATATTAATT +TTGTGCAGGTCTCATATATTTTCCAAACTCTCAGGCTTACATCAATCACACTGATGATCA +AGAGCGAAGAAAGGACGAGGATGGGCAGAAACATCACACAGTAAGTGTAACATTCTCACA +TGTCCAAGACGATCAGTTCAAGTTGGTGTCTGAGGCCAACGGAACTGCTAACAATCCATC +CTGAAAGCAAGGGTGGCTTCCTCGGTAAGTATAAACTATAACATTCCAAATCAGGCCCAA +AGTACCTTTTCTGGAGATTCACACAATATATTTTCTGGTTTCAGATCACGATGAGCAATG +CCTGACATGACAAAGAGCAAAAAAATGGTTAACATATGCAGATAATTATCAAACATTCCA +CACACAATTAATTTTTTCCAAATGCTGTAGTTCGCAGATTAATTCCCAATTATGGTACAT +TAAAAAATCAACGAGCTGCAGGAGGCAGAAGTAACCAGCGACACAAACCAAAAGCACAGT +TGATTCTGCGGGTTCTTTTGAAGAGGAGGCTTTAGAAGTCTGGCAGGGATAAGAAGGGCT +AAATGAATCCCAGCCAGCCTACCCCTCAGTACCACAGTGACCACCAAGAAGAAGGCCTAA +TGCAGAGCAGAGCAGAGAGCTCTGCAAACGGCAATGCTTGGAACAGCAATGCAGAAATAA +TTAGTGCCTTGTTTAAGAGCATCTCAGGGGGCTTAACTGCTCTACCTCATTTCTTCTTGT +GTGGCCGATTTAAAAAAAAAAATTCCTTCAGTGCGACTGTCTGAATGTTCAGAGGAGCAA +GTGTTAGTTACCAAATCTCCCAAAGTGACCTATTCCCTTCTCACCTGCTTTGCATGTCTA +AGGCAGCCCTGCCAGCAGCAGAGCAAAGACCGCTTTGGCACCAGGATGCTGTTATTTTTG +TTTTTTAAAATAGAGATGGAGTCTCGCTATAGCCAGGCTGTTCTTGAAATCCTGGCCTTA +AGCAATCCTCCTCCCTTGGCCTCCCTAAGCATGGGGATTACAGGTGTGAGCCACCTCGCT +AGGCCCACTGAGGGTTGCTGTTTTTAAGAGAAAACCTCTGCACTTTGGCCAGGCCTCCTG +AAGGCGACTGGAGATAGCAGCTTAGCCCATGAGGGGTTAACCTGCTGACCTGGCCAAGAA +GGCACCTCGGGGAGAGCCCTCTTCTAACCAAAGAAAGGGACAAAGAACTAACTCTGGGTC +ATGGTGTTTTGGTGGAGGACACAGAAACCTCCCTTTTGTCTTTCCTTCCACAGCACATGC +AGCACAGAGACAGGGCTGGAAGGCTGAGCAAGAGTCAGAGCTACAGTTGGAAGTATTGGA +AAGCGGCAGCGGATTCTCGGGGTGATGGGAAAAGCAAAATCTGCTTCACTAAAACTCCGT +CGGTGATCAACTTTTTCAGCAGTCCTCCGATTCCCGACTAGAAGGCAAAAGCCTGGCCCA +GGCCACGGGAGGCACTTCACTAAAGAAGAAAAACCTGAGCTCCAGCAAGCTCAGTAACTT +CATCAGTCACCTAATTGAACGAGAACCCAGAGCAACTCAGTCCAGGCTGCACAAATTGAG +TAGCACTGCTCTGCAGCTCGCTGCACTAAAAGTGGAAGATATTTTCCATTACAGCAAGTG +CTCCCACAGAAGGATCACGAGCCACACACGGAGCCTTACTCTCCAAATAGGCGCCCATGG +CCCAGTCGTCCCTTAGCCTAAGAACTCAGAGAGCCAGGCTGTAATAATGGGGCTGCCGTG +TGAGCACAGCAGCCATCGAGCTGCTCCGGTTCATTTCCCAGAGGTTGAGCTGCAGTGTGT +CCAGTATTTAAAAGTATGGAACTTGTTTCAGGGCTGACCCATTCTTGCCCAATTCATCTT +CCCCGTGTGAAGTTATTTAGCAAACAGCCAAGTTCAGCTGGAAATCGTTTTTCATCCCCT +CCAACTTCTAGTCACATGGGCAGCTGGCCAGCTACATGTTAACAAGCGCCTCAGAACTCC +TAAGACACCACCGGCCTCTGTTCCCTTCAGTGCATTCTTGTAAATAAATAAATAATAAAA +CCTGCCTTTACCACCCCCTCCAAGGTGTGGATCTTGTAAAAAGCGTGACCCAGTTTTGCA +ATCTACAGAGGCAGCTTGGGGAGCAGTTGTAAATCTTTGTCAGGCAGGTGTTACCTCTAT +GCATCCCAGCTTTCAGAAACAGAGCTGATGCTATTCATCATGCTGCGGAAGGTACAGACA +CCCCCTTCTAGTTTTCATCCTAGGTGCAAGTCAGGGCCCCAACATGGGCACTGTCAGTAT +GCAGACCTCTTTCAGCCACTGGAGGAGGGAGGTGGGGTCAATGAACCTGAACCTCCTGGA +CATGCGCCACACTGGTCTGCACCGGATTGTGGGCACCAGGTGGGATGTGTGAGTGGCATG +CCTACCACTGGTCCCGGGCACCCACAACCAACATGGCTGGCCAACATCCGCAACAGCAGA +GGGGGCAGACCTAAGTCACAAGTTATTCATTTCACTCCCACCCCCAACAGGCAGAATGCT +TTAAGGGAATTAATATTAGGAATAAAAATGCTTTCTTCCTGGTGGGAGGTGAGGATGGAG +GAAATCGTTATTTATTGAAGAACTATGACATACCAGGAACTATGCTCCATCTATGCTGCA +CATATACAATACAAACACAAGATACACATTTTTCATCTATAAAAAGCTTAGAATAGTGCC +TAGCACATACCAAGTGCTATATAGTGTTAACTACAGTCGATGATGTTATTATCTCAAATT +CTCACCATAGGGTAGGCATTATTACTGAGAGAACACATAGCTAGAAGAAAAGTGAAACCA +GAATTCATTTTTTCCAGGGTACTGCTGTTAGGCAAATTTAAAAAAAAGTATGTAATAGTC +AAACAGATTTATGGAAATGTAAAAACAATTTGTGGAAAGATTTAATTCACTACAAAAGTT +CCTGAATAATCAGTCATAGGAAAGGGGCTGTAACCTGAAGCGTAAATCAAATACTAGTAA +CCTGTGAGTTACCAATGTGCTTTTCAACAGATACCTCAAATGTACATGTTAATAGAAAAG +TATAAGCTGGGCACAGTGACTCACACCTGTAATCCCAGCACTTTGGGAGGTTGAGGCAGG +AGGATCGCTTGAGCCCAGGAGTTTGAGACCAGCCTGGGCAACAGAGGGAGACCCCATCTC +TACAAAAAAATACAAAAATTTCCAGGTGGTGGCACACACCTGTAGTCCCAGCTACTTGGG +AGGCTGAGGTGGGAGGATCACTGGAGCCCAGGGAGGTTGGGGCTGCAGTGAGCCCTGATG +GCGCCATAGCACTCCAGCCTAGGTGACAGAGAGAGACTTTGTCTAAAAAGGAAAAAAAAG +GAAAAAGAAAAATAGATTTTTCATTTACTGTGAACAAGATATATTAAACTACATATATCC +TATCATGCCAATTTTGAAAAGAGACAGAGGTGATGTATATTTTAAGACTAGAAGGAATAA +CATCAAGATATTCACACTAAGAAGGTTGTATTGTGTATGAGCTTTATATTCCTCACACGA +TAAGAATCTAAGAAAAGAAACATCATCCACACACAGTCACACATACCCTGTTCAATGTGA +AATTTATTCTTTCTCCTCCCTGCTCTTTCTCCTGTATCCCTGTGCTGCTCAACAGCTTCA +CCACCCACCCACCATCCGCAGCATAAGCCTAGGAGCCATCCTGGACTGTTTCTCCCTCAA +CTCCCATGGGTGAGCATGTTCACACCTCAAGCTGCCTTCCAGCCACACCATCTCCTGCAC +CAGCCCTCTGCCTGGCCTACCACCTCCCTTGGTACCCAGAGGCTGGCCAGCCCAACCCAC +CCACCAAGGCAAAGGCTGGGTTCACCTTTGGTATGCAGGAAGTCAAGGGCAGCAGCAACG +TCCCGCACCACTCGGCTGGCTTCTCGCTCATTGAAGTGCTTTTGCTTCTGGATGTGGGCT +AAGATGGAACCTGGGGAGCAGAGGGGACATAGAAGAATGCCTTTTTGGGCTCTAGTAAGT +ATAAGTTTTTTTTTTAGACGAAGTCTCACTCTGTTACCCAGGCTGGAGAGTAGTGGCACG +ATCTCGGCTCACTGCAACCTCCGCCTCCGGGTTCAAGCGATTCTCCTGTCTCAGCCTCCT +GAGTAGCTGGGATTACAGGCAGGCACCACCATGTCCAGCTAATTTTTGTACTTTTTTTTT +TTAGTAGAGATGGGGTTTCACCATGTTGGTCAGGCTGGTCTCGAACTCCCGACCAAGTGA +TCCGCCTGCCTCAGCCTCCCAAACTGTTGGGATTACAGGCGTGAGCCACTGCGCCTGGCC +GTATAACTTCTTAGAGGCCAAGTTTTCCCAAGTTTGGAAAACTTGGGGTGGGGACATAGG +GATTCATCGCTGACTCATCACTACCTGTCCAGCTCCAAGTGTGGGGCCTGGTACGGAGGA +GGTACCAGCTTGTATGTCTGTTAAACAAAACTGGACTACTCTCTTCTGTACCTGTCTATG +AGGAGCTCAGAAGCGAGAGAGAACAACTATAAATAGGGCCAAAAAACACTAATGATGCTG +AGGCTGATTTGGCTTCTGCAATCAAAAGGAATAAAACTGAAGGCACTTGGAGCTGAGGGG +GCCTTTCTGCAGCAACGTTTTCTCCCCTGCATCTGATCTCTGATCCAAACAAGAGCACAA +ACTTTCAAATGGAAATGCCACACCCTTGCCAGACATGTAAAGGCCTGGGAAAAGGGGGGA +AAAATGGGTTTTCCGCCTGAGCTTTCCCATTCATTATTGTTTTGTTGGCAATGGCTAACA +TTTACTGAGTAGTTACTAGTGCCATGTGCTATGGAATACTCTTGAAATAAACTGTCTTAT +TCTCACCACAATTGGACAAAATGGGTAGTACACTTATTCTCGTTTTACAGAGGGAGATCC +TGAAGCCAAAAAGAAAAATGGTTGAGCAACTTGCCCAAGATTACGCACCAGTAAGGGGTG +AGGCCAGGACTTAGGCCCAGGGCGTCAGTCAGGCCTCCGAGTCTGTGCAGACATCCCCCA +GCAGGACTTGTGGTCTGACTGCTGCAGGGATGGACTCTCTTGAGCCAACCACACTGGGTC +TGGCCTCAATAAGCTACATTAAGTTTACTGATATGGCGACAGAGGATCCCATCTGCATGT +AGCATTTCAAACATGTAATTAACAGTCAGTCATGTGTTATTGGGTGGTGCAGGGGCAGAC +ACAGGCAGGAACATGTGGCTTGGCTTCATGTGGTTTATGTTTACTACTAGAAGCCAGCAT +TTCTGGGCTGAAGGTATTATCTCTCTGTCCTAAAAATGGCACATGTCTACTGTTTTTTAG +GGGGGATGGGGAGGGCATGAGAGAAGGGGAAGAACTGCCAAAGATTGTTCGCTTGCCAGA +TTAAACAACGGATCCCAATGTGCTAGGGAACATTCCCAGAAAACCGGCTCATGACTAGGT +CCTAGCTTGCTCTGCTGTAGTGAGCCTCGTTTCCAAATCTGTTAAAAGGAAAAGCAGAGA +ATAATGCTTTACATACTTTTTTTTTTTTTTTTTTGAGACAGAGTCTCACTCTGTTGCCCA +GGCTGGAGTGTAGTGGTGCGATCTCGGCTCACTGCAACCTCTGCCTCCCAGGTTCAAGCG +ATTCTTCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGCATGTGCCAGCACACCCAGC +TAATTTTTGTATTTTTAGTAGAGCCGGGTTTCACCATGTTGGCCAGGCTGGTCTTGAACT +CCTGACCTCAAGTGATCTGCCCACCTTGGCATCCCAAAGTGCTGGGATTATAGGCGTGAG +CCACTGTACCTGGTCTACTCTACATACTTCTAAGACATCCCCCAGCATACCAAATTGTTT +TAATAATATTAGCAGCCAACATTTATTGGGCCCTTAGTGCCTACCAGACACTGTCCTAAG +CATTTCACATGAATTATCTCATTTAATCTTCACAGCAACCCAGTGAGGTAGGTGCTATCA +ATATCTCTATTTTATAGAAGGGAATATTGTTTAGAAAAGGTTAAGTGACTTGCCCAAGAT +CACATGGCTAGTAAGTGATGCAGCTAGACATAACATAAGCTTTAGCTGTGTTGGTTTCTA +AAGCACGCTCCCTCAACCACCAAGCCCCTCCGTGTGGCCCTCCATGCAGTTCCAGACATC +CCTGCAAGTGTGTCCTAAGATTGGGGGAGTGATGGGAAGGGAAAGGGTTTCTCTACCCCA +CCTCATTATGTCAGAAAAGCAACTTAAGTATACACCCCAGTGATTATGTGTGTGGGTGAT +GGCATCTTTCCATCTGAAGGATGGCACATTCTCAGGCTTCCCCTTTATCCTGGGTCTGTG +TCCCAAACAATAGGACCCTCCTCTCCTCTGTTTTAGCCTTTCTAGACTTCGCAATGTATT +TGAGAGCTTCCACCCCATAATTAATGTAGTTAAACAGTGAACATGTCAAAACGGGATTGA +TAAATCGATGACTAAATGTATCTATATATGACTCCTATTATAATGAAAAGGCATTTATAA +AATACCCACACAGGTGACATTCTAAGCTCTGCAAAATGCTAATTATCATCCTTCCCTCCG +GCCTCCCTTCTCCCAAATCAAGGGCAGTTTTTAAGTCCTTCATCCTTTTTATTAGCTTGA +CTCGTTTTGGAAGTCTCTGGGATTCATGATGGATGATCACCACCCTGGGTCTTAATCAGA +AGTCCACACACATACTCAACGGTAAGTACCTCCTTGCAATTTCTCAAAGACCAAGTAAAA +CCTTGTGTCATCTTCAAAGAACTCAATCAGCTCCAAAATGTTCCTTAAATAGGGAAAATA +GGAGGAGAGGGAAAAGGGGGGAAATGGTATTATATATTAAAGTCTACTTACAAATATACA +ATGAAAAAAATATACAACACCTGGTAGTGGGGCAGAAACCAACTTGAAATCAGAATGCTT +ATTAAAGACCCGCGTATGGAAGCAGCCAATGGTGTTAGCAAGATTCAGGTCACCTTATCT +TTCCATAATGTTTAGTCTCTGGTGTTTTCACCAAGTCTGTGCTGTCAAACCCCAGCCCTA +AAACCCACTAGGTAGAGTTATAAAAAAGTCCCGGTCACATTAAACTGAATAAAATCTGCA +GCCGACTGGAAGCAATTGCGGCTAATAACACTGAATACTAGGTGTGTGTCCTGGAGGCAA +GCAGCAAATAATTACTTGCCCTCCCTCTTGCCCATAAATCACGGGGCAGTATTTACATTG +CCTGGAGAAAATGGAAACATCTGTCAAATGGACTTGGGGCCTAACATGGGCACCGCTAGA +CCCTAACTGCTAAGCGCTGCTTAATGAAACGGCCGCGTTCCTGGCCACTGTAGCACTTGT +GGCCTTCCCCGGTGAGCACTCTCTGTCTGCCCGAGTATTTCAGTGCTCTGCCAACAAGGT +CGTCTTGTAACTCAGTAGGGAAGCCACCAGCCTGGATATTGGAGGTGTTGTGGGCTTTTT +TTCTTTTACAAAATAAAATAAACCAAGTAGAGTCTCTAATGCTGAACTAAGAAGCTGCAG +GGCTGAAAATAAAAATCTGTCCCTCATAAAAAAAATGCTGACTACTTTGGGAGATATGAG +GCTTTTACTAGTGTGAAGGCATCCAAATAAGATGGGCAAAATGGCCTAATTTGAAAGAAG +ATTGTGGAGGCAGTGCCTGGAGTTAAATCAACAGCAGCCCCCGTCCTCCAATCCTCCAAG +CTTAATGACAAAGCCATCAATACCAGGCCACTGGCTCCCTGCTGACCCTACCGTGGAGGG +AGAGAGGGGGAAGTGGAGTCTTAGAGGTGCCCCTGATTTAAAGCCACAGTGGGAGAGCTG +CTCATTTGGAGCTGGTGGTGGGCAGAATGAACTGGGGCTAGAGATGAGCCGGACCCAGCT +ATCTGGAAGGTTCCAGGATCTTAGTGGTATCTGCACATATGTAAACATTCTAGGAGCAGA +AACAGCAGCAAATATTCTTAACAGTTCTCCTCATCTTGGTATTAAGGCAAGTCCTTAAAG +ATTTCTACCAGGCAACACTCAGTCAACCTAGTTTCCACAGGTACCGAAAGAAATAAAACC +CCATTTCCCCCCAACAACCACTGATTCAGATAGTTCATTCTTCTAACTTGCTTGAATTGA +TGATATTTACAGTATTTCAGAAGAGATAATAGCTCCTTTGCTGTTACTGCTGCTTTTCCT +TTCTCTCCCTAACACTGAAAGGGGCGGAAGGAGGTACCTGCCTTGTGGGGACAGGAGTGA +GAGCTAAATGCTGGAGTCAGGAGATGGTAAGAAATAGCCTCCTCTTCTGTGGCCAAGCGT +CCCCCCAGAGAAGCAGCGAGAATCACATGATACTCACTTGTTTCCCTGACACTGATACAG +CGTCTCCACCTCTCGAAACACCCTACTCCGACTGTGCCCTGCTTGTTTCTCGATGATCTG +TGGGAAGAATAAAATCTGTCATGTACACCCACCTGACTTCCAAACAGCCCTTTGGCAGGA +GTCCTCTGGGAGAATGCAAGGCCACACTCAGTCCAAATCCAGTGTCCAGCAGAAGTCTGG +CCTAGGCCTTGGTGACACCGGCACTGTGGCTCTGTTGGCAAAGCAGCAGACTGGCCTCAG +GGCTTTCCAGCTCAGCTGAGCCCATTCCACTCTGGCCAAGCACAACACCAAGGAAGTGAA +TGAGGCTGCTGCCCCCAGCTGCCCAGGGGAGACTGAGGCAGCCGGCAAGACAAAGAGCTA +CCTTACTCAGCTCCACCTCCTGTGGACACCTCTTTCTGCCTTAAGGGTAAGCATTTACTG +CATCTACTGAAGGATCTTCTCATGCTGGAGGGAGAGGCTGATGCAGGACACCGTGGCGAG +GAGCTAAAGCTTTGACACCCAGCTCAGAGGCTGCCTCCACGATCCCCCTGGCAGAAGTAG +GCTCTTCCTCTTCTGAGAACTTACTCTCTGGCAGATACTGTGTTAAATGATTTATTTACG +GCCGGGTGTGGTGACTCACACCTGTAATCCCAGCACTTCTGGAGGCTGAGGTGGGTGGAT +CACCTGAGGTCAGGAGTTCTAGACCAGCCTGGCCAACACGGTGAAACCCCGTCTCTACTG +AAAATACAAAAAAATTAGCCAGGCGTGGTAGTGGGTGCTTGTAATCCCAGCTACTCAGGA +GGCTGAGGCAGGATAGTCACTTGAACTGGGGAGGCGGAGGTTGCAGTGAGCCGAGATTGT +GCCATTGCACTCCAGCCTAAGTAACAGAGAGACTCCATCTCAAAAAATAAATAAATAAAT +AAATAAATAAACAATAATAATTTATTTACATAATCTCAGTTGACCTTTATGACAACATCA +AAAGATAGGGAGGTATGAAACATTTGCCTGCAGTCCAGAGCTGACTCCTAAGCCCTTGCT +ATCCCATACCTGCTTAGATGCTCTAACTTCTTCGAGGACCTGGAGGCTTTGTCTCTCCTG +TGATACGGTGGGCTGCTCCCCCTCCACACTTTTACCTGAGATGCTTGTCAAATGCTGACT +GAAGGAACAGATAAGCCAACAGATGGGAGGGTGGTTTCCAAAGGGACTGGCTGCCTCTGC +AAAGCTCTCTGGACCCATCTGGAGCCTCAAACCACTGCACACCGAGCCTGTGAGCAAATC +TGCAGAGCCTAGCTCTGCCTTACAGCTCCAACGTGCACAGTGGGCAGCACAATGACATCC +TCTTCCTTCATTGAGACTTCAAACTTCTCCGATATGATGTGGCACAGACATCTGTGACCA +ACTGCAATTTTCTAAATAAGTGTGTCTGTTTGTAAACCACAGTGGGCCCATTATCTGAAT +GGAGAGGTGTAGTGCTGGGGAACAGAAGTGATTCAACTTCATTCCCCAAGCATTTCAGAT +CAAAGTCATGAAGAACTTTCTAGCAGGCAAGCCTTCCACAGCACAGTCTTCTCTGAGGAA +GTAATGGGCTCTTGCTACTAGAGATGGGGGAGCAGAACATGGACAACTATCTGGGGAGTC +AGAGGAAATTCAGGGTTATCTTGAAATTCCATCCCAACCTTGAGAGTCTAGGATCAGCTG +GGTGCCTATAGGAAAAGCTGTAATAAGCTAAGTATTGTGGGGCCATGTTGGGAGAAGTAG +CCCATCTCTAGGGAGCTTTGAAAGAGTAGGGGAGAGAAGAAACATGGGCAGAACTGCTGA +AACCAAGGAATTGCCAAGCCAGAGTCCAGTGTTTGCCTCAAAGATGCCAGGGGGGATGTG +GAGGAAGGGCCAGGTTTTCCTCCCATTATCCAACCTTGAAGAAATATACCTCTCATCCAT +AAATGTATTGAAACCTTTGAAAATCAGTTTATGTTTGTGGTTTTTACCGCATTTAGACAG +ATATATCAATTTTTTTTTTTTTTTTTTGAGACAGAGTCTCCCTCTGTTGTCCAGGGTGGA +GTGCAGTGGCACCATCCTGGCTCATTGCAACCTTTGCCTCCTGGGCTCAAGTGATCCTCC +CACTTCAGCCTCCCAGGTAGCTGGAATTAGACGCACATGCCACCACACCAGGCTAACATT +TTTTTTTTCTTTTTGTGACAGAGTCTTGCTCTGTCGCCCAGGCTGGAGTGCAGTGGTGTG +ATCTCGGCTCACTGTGCAACCTCTACCTCCCGGGTTCATGGGATTCTCCTGCCTCAGCCT +CCCAGGTAGCTGGGATTACAGGAATGCACCACACCCGGCTAATATTTTTGTATTTTTAGT +AGAGATGGGTTTCACCATGTTGGCCAGGCTGGTCTTGAATTCCTGACCTCAGGTGATCAG +CCCGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACATGCCTGGCCTAATT +TTTCTATTTACACTTAGGCGTATGTTTTAAAAATCACTTGTAATTTATACTGAGCTGTTT +CCCAAAAGAAATTAAGACAGTGCTCTTGTTACCATGTGAAGCAATACTCCAGCTGAAAGG +AACGTGGCTTAGCAGACTTGCTCAACCTTCTAACCCGCAGCTGGGACTGTGGAAAGTTGG +TTCAAAGAAGAGAAAACATTTCCTTCAGGAGCCCACTGGGCTGGGATTGCCAATGTGAGG +TGGCATTTGACCTGGTGGCTCAGGTGGGTGATTTGAAATCAGCTTGGATTTAAAAAGACC +CTTTCTCTAGGTCAGTTAGTCCTCAAACTTTGGTGGCTATGAGACTCAAGTGGGGAATCT +GGTCAAGCCACAGAGATCCAGACCCTATCCTACATCTGGAAACCTGGATCTGTGTGTGCT +TTGTTAGAGCTCTAAGGGCTTCTAACACATAGTAGCATTCACAACTGCCCTTCCTACAAC +AGTAGTCCTCAAGGATTAGTGAGTGTCAGAGTCACCAGGAGAGTTTGTTAACATTTGTAT +TGCTGGGCCCACCCCTGTTTCTGAGTTGGTACTTCTCAGGTAGGGCCAGGTAGCTTCTAT +TTCTAACAAGTTCCCAAGCGATGCTGAGGCTGGTCCAGGGCACACATTTTGAGAACCACT +GCTCAAGATCCAGCTCTTCTTCCATGTGGAGAGGGCAAGTGGAGGCACAGAGGGGTGACA +TGAGCCACTCCAAGGCCTTACAGCTAATTAAAGGCAGCAATGAGGCCAGAAGCCACTTCT +CCTGCCCCAAAACTGAGTGCTCAGTCGCTTTAGTTTTGTTTTCTTCTTTTAATTTTTTTT +TTCTGAGACATCATTCAGATGTTACCAAATCAGTCACCTTAGTTTTTAATCCTCACTATC +ATGCTAACATCTAACACTTGGATAGCATTTTGTGACGTGTAAAGTGTTTCCACCTCTCCC +AGGATATTTTAATTTTCATCTTCATAACTGCCTCAGGAGACTGAAGGGCAGGTATCATCA +TTTAGAGATGTAGGAACTGAGGCTTACGGACATTTGATGACTTGCCCAAAGTCAAACAGT +TATAGTTTGTCAAAATAGATATTCAGGTAGGCCTTCTAATTCCAAATCTGGTTGTCCACT +CCCTGAAGCTGACTTCATTTGTCAGAATAATGAGAAACTTACTATGAGCCAGGCATTGTG +CTAAGCACTTTACCTATATTAACTTATTTAATCCTCACAACAATTCTACATAGGTTCTAG +TATTATACCCATTTTACAGATGAGAAAACTGAAGGACAGAGAAGTTAAGTAACTTGCCCG +AGGTACACAGTAAGTAGAGAAACCAAGATTTGAATCCAGTGAATACAGCTTCAGAGTCCC +CATTCTTATGGAATATAACATTTATTTGGTTCAAGATGAGCTAGGAATGACTATTTGCAA +AGTAAAGCCTGGCATTCAGCTGAGACACTCACTTTGACGGCATACTCTTTGCCATTCTGT +AGGCTCACGGCACCTTGAACTTTGGCATAGGCTCCCTCTCCAAGCAATTCAGAGGTCAGC +TTGTACATATCTAGAGGTGAAATGGATGAGAGGAATAACAAGATGAGTCACCCTACTGCA +AGCTCAGATGGGAAGAACTTTTGTGGCTCAGCTTCCCTGATCAGACGACACAGGCACCCA +ATGACTCTAGCACTCAGTGACAAGGAAGACAAGTAGCTTTCCCAGCCACCTGAGGACCCA +GTTTCTCAACAACAAGACCACATACAAGGCATCCTGTTCCTCATTTTAGCGATGAGGTTA +GCAAAAGGGTCTCAATTCGGCACATACTTCCTGAATATCTACTATGTGCCAGACAGCATA +ACAGAGTAAGGAATAAAATAAAGGCCAGGTGCAGGGGCTTACACCTGTAATCCTAGCACT +TTGGGAGGCCAAGCCAGGAGGATTGCTTGAGGCCAGGAGTTCAGAACCAATCTGGCCAAC +ATAGCAAGACCCCATCTCTAAAATATATATACGCATGATCCCTCTCCTCTAAGGGTCGCA +GTCCAGTGGGGAAGACAGACACATACACAGGTGACCCCAGAATAAACCAGGCATTGGTAA +ATACTATCACAGAGGGACAAAGTACAGTTAAAAAAAAAAGTTGGGGGAAGAAAGGGTTAA +ATCTGTTCAGAGAGGCTGGGCATGGTGGCTCACACCTGTAGTCCCGGCACTTTGGGAGGC +CGAGGTGGGCAGATCAAGAGGTGAAGAAATCGAGACCATCCTGGCCAATGTGGGAAACCC +CGTCTCTACTAAAAATACAAAAATTAGCTGGGTGTGGTGGCACGCGCCTAAAGTCCCAGC +TATTTCGGGGGCTGAGGCAGGAGAATCGCTTGAACCCGAGAGGCGGAGGTTGTAGTGAGC +CAAGATCGTGCCACTGCACTCCAGCCTGGTGACAGAGTGAGACCCCATATCAAAAAAAAA +AAAAAAAAAAAAAAAAAAAAATTGGTCAGAGAATCTGGAGGATCATCAGAGGAGAAGTGG +TATGATTTGAATGAATATTCATTTACTCATTTACTGAGCACCTATTATGTGCCAAGTTCT +GTGTAAGCACTGGCTATACAAAGGAGAATAAAACACTGTTCTATTTTATACCCCATACAT +GGAAGTCATTGGAGGCTTCTGAGAAGTCTCCAGAAGTCACCCACAGGAAATAGAAGTAGG +ATGCAAAGGACACCTTGAGGTTTTTAGGGTACTGAGTCATAGTTGTTCTAACAGAGTAAT +AGACCTGGGTTAAAGGAACATCTAGATGACCTGCCCAAGCTCACAAAGAGCACAGCTCTT +TGAGCCCCTTCCAAAGGAGGCTACATCTCCATCACAGCACTAGCTGCCTGACCTCATCCC +CACTCGGCCTCCATTCTTCAGCCTTTTCCTCTTGAGGCACCTAGCATTGAAACCCACAGC +CTGAGCAGAAGACATTTCAACCATGAATTAGATTTTATCACTCTCAGTCAGGAGAAGTCC +TGTCATTGCACAAGCTGTCCTTAAAAATAGGAAGTACTCTCTTGTGTTAACTGAAAGAGC +AAAAGAGCTGTTGATTAGGAAACTATTTGAATACCTTGGGATCTTTGTCTCTCCCCCATC +CCCATACCCTGACACACACAGACACACACACACAGACACACACCCCTGCTGTTTGAGTTA +AAGGCAAACAAAAAACCCCTGCTGAAAGTACCTTCTTGGTTCCATCACGGTTTGGTCTTT +CAGTTGTTTATAAGAGCAGATGGCACACTGTTATTCGTAAGTGTTTTAAATGACATGCTT +CTCACAATGGACACATTGGCATTAGCCCTTTACACATATCAGGATAGGTGGGTGGCTGGA +GGTCCCATATTCCCAACCGATAAAGTGCTTGTTATTGGAACCACTTTACAGAACAGCCAA +TTCACTAGTGTGTCTGGAAGGCTGGAAGGAGGGACCAAGAGGCGAAGCTACTTCAGACCT +CACAACGAAAGAAAACAAAACAGATGAAGTGGGGCACGTTACTCCTAGGAGTAGCTACTG +ATCCTCTTGGTGCTTTGCACAAGTGTCCAATCACCCCATCACATGCCCAGTGATAACAGG +ACCCACACTGAGCCTAGTGCCTCGCACACAGAGAGTGTCAAAAAATGTCTGATGACCCAA +CATCGTTTCTACTGAACACAACACGTATTCTTTAAAATGTAGTCAAACACACACAGCATA +AGTAGCTACAATCTGAGAGACAAATTCTCTGCTTACAGGAGACTGAAGTTTCATTTGCGG +CCATGGCCTTTGGTGTTTCTCTCTTCCTCTTATATAGTTCTATCTCTCAGCAGCCCCTCC +AGGAATAGCTGAGGGAAGAATCACATCTGAAAAAAGGAAGACCCCAGGCAATGCCACTGA +TAGATGGGTCTTCCTGCTCCCTGAAAAGGAAGCAGTACCTGAGCCATTCACAGGAGGCCA +GTGCATCATCTGAGAGCTTTTTCCATCCCTGCTCTCTTTCTGTAATGCCCTGTGTAAACT +CCCTCATCCCCATCTTATCTCCCTACCACACAGATAACCACCATCTGGCTCTAACTTGAC +GCATTCTGTGATCGGACCTGTGGCTCCCGGGATGCTCCTCCCATGCTTGGGAAGCTGCAG +GCCCAGATATAGGGAAGTTGTGTGACCAACCTTCAAACTTTCCTGGCAAGGAGTCAGTGG +CCCGGCCCCTCCGCTTCTTCTTCCTCCTCCTGTCACCATCTGCGATGGGAAGGGGTTCGC +TACTGCCCATCTCTAGGAGATAAGAGGAGATGTAAGGGAAACATCACTGTACTGATCAAG +CTGTAAATTTACCCAGAAGGAAAAAAAAAAGGTAGTGGGGGAGGACCCAGGAGGTTTACA +CTGATGGTTTTTAAATATCTGTGAAGACTATTGATTTGTTTTGACCTAGGAGGAAAAACT +AAAGGCAAAGCCATTATGGGAGATCATTAACTGTGGAAAGGAGCTCAGACAGGCAGGCTA +GATTAAAAGAGGCCAGCGGAAGCCTGCTTTAACCAAGCTCATTAGCGCGTGGATTTAGAT +CTGCCACTGGTCAAACCATATTCCCCAAACAGAACAATGACTCCATAGGCAGAACCCCAC +CTGTGACATCCTCCAGCCTCAGCATCAGAAAGGCAAAACCGAGAGAGCTAGGCAAGAAGG +GGGTTGGGAGTGGGGGACCATGCAGATGAGTCATAGGCTCAGCAACATCGCTATGGATGC +ACACAGGGCACAAATGGCCTGGAGTGGAGACAGCCTCTGTGAAGGTAGCAATAGGGCTGG +GGTTCAAAATAGCCCCAAATTACTTCATGTCCAAGAGCACGGACTTGAGTGCCTATGGAG +CCTACGGCATCCTCTCCTCCCATAGCTCCTCCATCGGAAGGGCTGCAGGTAGTGCCCATT +CAGAAGTCGGCAGTTGACAGGTCTGTGCCAGGCTGCTGGATGAGGTCACTTATTGCAAAA +AACCTTATTATCTTTCATTGGCAAGCACCTGGCTCCCAATCTTAAAAGGAGGATTTGTGA +GGCAGGCATTCAGACACTGCACAGATTGGGCAGAAAAAGTCCGGATGGAAAGAATAAGCA +GGACACTGAGATAGGAAAGAGAAAAGGAGGAACAGTGAACCAGTGCCCAATCACAGTCCT +GTTTCTAAGACACTCTAGTATGGGCCTTTCCCTGTTAAAGATAAATTACTTATAGAACAT +GTCATGCCCCTGATCCAGAGTGGAGCTTTAATACTCTTTGCCTGCAGTTAGAAATAATAA +GATTTCTCCGAAGTCTCTGGGTCTAAATCCCCACCAGCGTGATTAAACCTTTACATCCTT +CTAAAATAGAGGCACTCGAGTGCTGATGGGGCATACGATGTGAGAGACTTTTAGACCAAC +CTTCAATAAACACAGGCTCTTGGTTGTTGGTGTTTTTTTTTTTTTTTCTTTCTTTTTTTT +CTGAGAGCTTTTAAAATGGAAGCTGGTTCTTTGCCCATTGAGGGGAAAGGCCCACTCTCT +TCTCAGAGGATCTGGCGGCATACGACCAGAGAAAGAGCAAGTCTGCTAGGAAGACTGATT +AGTGCTCATGCAGGTCCATACACTGTTCTCAGACGCAAGTACGTGACAGCCATCCGGAGA +GAGCACACAGGATGGCACTTTCAACACCACAATCCAGAAAGCATGGTTACGCAGCCAAGT +GCCTGACAGCTCAATTTAGGCGCATTCTTCCATCCATTTTGGGGATCTGATGACAGCACA +TTTTAAATTATAGTTTAGAATGGGGAACAGATAAACACACAGATAAAAGAAATCCACAGA +GCATCTCAAAATATAACTCTAGCCAAGAGCTTCAAACACAAGATATATCTGGGGACTGCA +ACACCCTATGAATTGAAAGAATTAAACATCTGGCTAGGCACCATGGCTCACGCCTGTAAT +CCCAGCGCTTTGGGATGCCGAGGTAGGCAGATCACTTGAGGTCAGAAGTTCGAGACCATC +GTGGCCAACATGGTGAAACCTGTCTCTACTAAAAATACAAAAATTAGCTGGGTGTGGTGG +CGGGTGCCTGTAGTGCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCGCTTGAACCTGGG +AGGCAGAGGTTGCAGTGAGCCGAGATCACGCCATTGCACTCCAGCCTGGGTGACAGAGCA +AGATTCCGTCTCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA +AAAAAATCAGCACCTCAACACCCACCCTCACCAAGGTAAATTAAAAGGAAAAAAGCTGCC +CAAATGTATAACATGGTGAGAAATTCAGCAGAAATAAAACACAGGGTCACTCATCTTCAG +GAGCTCAGGGAGGGGGTGCTGGCCATCGGGGCAGCAGGCTGAGAAGGAGGAACCATTGTC +TCTCTCTCTTGCGCTGACCTTGAATGCAGTCCAGTGGCAACCCGTGTCTGCATCTATTTT +CTCATCGGCACCGCAGGCCCAGTGCAGAGGAAACAGATTTGGGTTTCAGCTCTTTCTCCT +TCCCCTGTCCACACTTTGATGGAGGGCCCCAGGACAAGCAAAACAGCCAAAAGACAGGCA +GAGCAGAGGAGCAGCAAGAGGGCTGGAGGCATTATAATTCACAGGGGACACTCAGGCACA +CGACTCTAATGAGAAAACCCTGTTAGCGACAATTTATACTTGGTCTTTACCACAGCAGGG +CTGAGGGAGCCGCTTGCACGAGAAGCATACCTCACAGCACCACCGCACACGTAACATTAG +ATTTTATGGCTTCACACACACACAAAGACAGAGTACCTGGTATATTCTGCATGGATTTCA +ATGAAAGAGGGTACGCCAGAAGGGACAAATGGTTAAGACTTTCCTTGGAAATGGAACTTG +GAGAGTTGTTTCTGAAACTAGGAAGGAAAAAATGTAGGAAGATGGGTGAAGTGAAAGAAA +CATGCTTAGCTTCCCTGGTTACACAGGGGGAAGCGAGAGGTGTCATAATCTCACCAAGGG +GTCGCTAGTTGCCCATGTGGAGCCTGGCCACACACTATTTTCATCACAGAGTCCACTAGC +AGGTCTGTGGGGCCTTAATTCATCATGCAAACACTCATGGGATAAATGCTGCCTCAGGGA +GTGGGACCCCCGCAGTAAAGCTGCACCTTGGCTCACCTGCTTCCCTTGGCCTAGGAATTC +TTCTTGGTCATCAAAAGCCGGCTCGATAGTCCCAACCCTTTTGCAGCTCCCTGATAACTC +CAGATGAGTTAAGGTTTCTACAGAGACTCTGGAAGTCAGTTAGGTGCTATGCAAATGGAG +GGTGTTACTGAGCAGAACTAGTAGTTGGTGCTCCATCCTCTGCTCCCAAACACCCTGCGA +GAAGCTCCACGAGGGCACTGATTTTATTTGGCCTTGAGTGCTCCCCTGTGTTCCTAAAGG +CTGAGATTGTCCCCTGTTCACTTGTTTCTCCTACAGATCATGGCACAGTGTCAGACACAT +AGCAGCCATCAGAAATTGCACTGAAATAGAAATGATATGAAATGACATGCATACTGTTAG +GTGTGGGGTATGTCACACTGGCCTTTTAGGTACCCAGTGCACATCCTGAAAGAAACATGG +GTACAACTTTGCCCTGTAGACAATGCAGAGTAAGGCTACTTAGTTTTATGAATCCAGTTC +AGGAATTCTACTAATTCCTGGATAAACTCCCTTTCGAAAAAGGGTCTAGGACACAAAACG +TCCTTCACTTTCTTATCTTTTCTTTTCTTTTTGAGATGGAGTCTTGCTCTGTCACCCAAG +CTGGAATGCAGTGGAGTGCAGCTCAGTACAACCTCTGCCTCCCGGGTTCAAGCGATTCTC +CTGCCTCAGCCTCCAGAGTAGCTGGGACTACAGGCACATGCCACCATGTCCGGCTAATTT +TTTGTACTTTTTAGTAGAGACGGGGTTTCGCCATGTTGGCCAGGCTGGTCTCAAACTCCT +GACCTCAGGTGATCCGCCTGCCTTGGCCTCCCAAAGTGCTGGGATTACAGACGTGAACCA +CTGCGCCCAGCCAGGTCCTTCACTTTCTAAACAGAAGCCTGGTTCTTGCTATAGGATTGG +GCAATGTGTCTGTTATTACAGAGGAAGAAGTGAGCACTTCTTTTCAGTTTCAGGCAGATC +CCAGCTGGTCTGGAGGCTCCCAGCACTTCCGCTGCCTCCAGCCCTTGCCTTCCTCTTGGG +AACGGCTCGGCGGTCCACCACATGTGTCTATTAGTGGAGGTGGAAGTGGAACTGAAGAAG +CAGCATGCTGCTTGCTGACAGGGAAGGCACACAGGCTTGGCATCAGGCGAGCAAGGCAGA +AGCCCTGGTTCAGATATTATAACAGAACCAAGGCCAAGTTACTGTGCCTCTTAGAGTCTC +AGTTTCCTCATCTATCAAATAGGTTTAAAAACACACCCGCCCTGTCTACCTCACAGGTTG +TTGTAAAGACCCAATGATGGCCAGGTGTGGTGGCTCACACCTGTAATCCCAGCACTTTGG +GAGGCCGAGGCAGGCAGATCACCTGAGGTTGGGAGTTTGAGACCAGCCTGACCAACATGG +AGAAACCTCGTCTCTACTAAAAGTACAAAATTAGCCAGGCATGGTGGTGCATGCCTGTAA +TCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATTGCTTGAACCCCGGAGGCGGAGGTTGC +GGTGAACTGAGATCGCACCATTGCACTCCAGCCTGCGCAACAAGAGTGAAACTCCGTCTC +AAAAAAAAAACAAAAAATACCCAATGATATACTTCACATAAATATGTTTCCAAAAACATA +TGCATATGCACAGGTATGTATGCCCATATATGAACCCAACAGAGTAGAAAGACTAGACAG +AAATACGTAAAACTGCTAATACGCTACAATTTTAAAAAGTGCCAACTACATGGATATTCT +GTACATATTATCTCTAATTCTTATCATAATCTCAAAAGGTAAATATTTTTGCCATATTTC +AGGTAAGGAAAGAAGCTCAGAGCAGGCAGCCAGTAGATTAAATAACCTACCCAATGCCAA +ACATCTAGTTAGTGGTTTAACTGGGATTCAAACTCAATGCTGCTCTTTCAAGTCCAGACC +ATTTCTAATCCATAAGAGTTTTCTCTATGTGATGGGGTGATTTTTATTTTCTTTTTTATA +TTTTCAGTATTCTCTAAATTGTACACAATGAAATTTATTTTTCCTGCTATTATTGTTTAA +CTCACGTTTTATTTTTAAATAAAGTACACCATAATCTTTCTCTAATACACATTGGAATTT +GGTATCTGATTTTAGTTTTTAAAAATGTTTCTAGATTTCTCTGTATTAAAATTCAACATT +CAGTGATGAAAGAAACATTTTAGGAATATTGGTGCCATGAAGATACTAATTTCGCAATCA +TTCAAAACAACCAATGTTATTTTTATTTTTTAAAAAATGCTACTTCTTGGCCGGGCGTGG +TGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCGGATCACGAGGTCAG +GAGATCGAGACCATCTTGGCTAACACGGTGAAACCCCATCTCTACTAAAAATACAAAAAA +TTAGCCGGGCGAGGTGGCGGGCGCCTGTAGTCCCAGCTATTCGGGAGGCTGAGGCAGGAG +AATGGCGTAAACCCCGGGGGGCGGAGCCTGCAGTGAGCCGAGATCGCGCCACTGCACTCC +AGCCTGGGCGACAGAGCGAGACTCCGTCTCAAAAAAAAAAAAAAAAATGCTACTTCTTAA +AAGTAAATATTTTATAAAAACAAATGAAAAAATGTGCTGAACATTGGAGCCTGAGAGCTA +TGGCTCTCCTCCACTGCACGAACTGCAGCAAGCTGCTTAGCTTCTCTGAGGATCAGTTTC +CTTGTATATGAAATGAGGTAAGCAGAAGGCCTGGGCTGCCCATGCCACAAGGCTGCTGTG +AGGATCAAATAAGAGACTAGAAGTGAAAGCACCACTGACTTACTCTTCAATAATGCTATA +TTTATTGGGCACCTACTGATCGTCTGGTGCTAGACAGTGAGAGTATAAGAGAAGACACAG +TCTCTTCCCTGATGGCGTTTAAATCTGCTGCTGACGCTTAAAACAATTTCAACATAGTAG +GACAAGTGCTGGGACAGGGAGGTACCAGGTGCTGTGGAGCAGGAGAGAGGAAGCTAACCC +AGTTGGGTAACTAGAGGAAGACACAGCTAAGCCTCAATACCTGAGGGATGAGTGGGACAG +GGCTGAGGCCTGGAAGAGAGTGTCCCAGACCAAGGAAGGGCACAGGCTGAGGCCTGGAGG +AGGGACACAGGGCCGGTGGGGGCCACTGGTGATCACTCAGGCTGGCAGGGGCACAGAGCA +CATGGGAGGAGGGATGACATTAGCTCACAAGCAGTCTCATCGTCATCGATGATAATAAAT +GTCTCCATTCCTAGGCATACGTTTATCTTGTTTTCTCCATTAAAATAGGAATGCATGTTT +CGTCTCTTTGTAAAACCTGTGAGTGAACGAGCACTGATGGTACTGAAGGTATAGTAAGTG +TGAAGGATACAGATCCAGGAATCATCCTGGTTCCTGCAGGGGAGATTTACAGAGAACTCA +TAGAGCAGATGAGGAAGGGTTATGGAGGCTCCCTAGAAGGACTACTGCAGCACAGAGATT +CCTGACATGCAAGCATCCATCCACCATTCTGCTCCAGAAAGTGACCTCGAGGCCCACCCT +CTGGAAGAACTGTGTTACTTCTCCATAGTCTTATGAGCCACATTGTCCCCAAAGGAACCA +GATCTGTACTCCAAATTTTGAAGAGCCTGCAGAGAACTCATCAGCTTTCATATCTGTGCA +TGAAACCAGAGATGATCCTCTCCCCACTGAGAACCCGACTTTGCTGGCTAGCTCAGCTCT +GCAAACTTAGCTCACACTCCTCTCCCAACCACTTCAGAATTCTTTTCAAGGTCTCCCCAA +CCTTTAAGAGCGATTTCCCTCAGCCACAAGAGCTTTCTTGAGAAGAAATAGTGGTGAGAG +CAAGCAGAGAAGTGTAATTACCAACCCAGCTGCCTTCTCGGGCATCAGCTAGCTGAGCAT +TCCAAAACAAATGGAGAACGGAGAAAATGATCAGGAACTGAGGGACTGAAAGGAAGTGTC +ATGGGCACTCTTAAGGAAGTGGCCAAGACTAAGAAATGTGACAGAGGAGGCAATGAGGGG +GTACCTGGGGAGACTGACCCCAGAACATTTACATCTTTGAAGTAGTAGCCGGAGCAGTAT +TAGAGTCCACATGACTACTCCTAGTAGTGACATTACTCACACACACACATGCTGCTTACT +GTAGGCCAGGCAGCATTCTAAGCACTTTACCAACGCTACACTTTACATATACTAACTTAT +TTAATCATCACTACTTTATGAGCTAAGTATCCAGATTTTACAGATGAAGAAACTGAAGTA +CAAAGAGATTAAATGATTTGCTCAAGGTCGCATAGCTTGTAAGTGGCAGAGCTGAGATCT +ACATCTAGATGGTCTGGCTCAGAATTCAAGCTTTTAACCATTACACTGTATTTAAACCTT +AATGCTGAAAGGCAGAAGGGGTAGCTAGTAAAAGTAGCCAGGCACCAATGAGAATGCTTT +TGTTTATAAACCTTAGCACAGAGCTTCCCTGCTGATGTGCTGTGAATGAGGTATTGATCC +CCTCATCAGGCCTCCAGTCACTCACTGTTACTTAGGTGTGCAGAACAGTATCATTTTCAG +CGTGTGCTATGATGTGAAAAGGTTGGGCAGCACTGCCCTAGCTTCTGGAAATATGAAGGC +ATTATTACCACATTATCATCGTCCTATTAATCAAAAACTTCATTTATCAGAAGTTTCTTC +TTCTTGCTCTGAGCTTGCCTTGTATTTTGTGTTTTGTCATCTTATGAAAGATGAGCTACC +AACCAAAGTCCACCTACATTATTTCATGGCAGTTCTGGTGTCAGGGACAGGCTACGTTCT +TCTGTCTGACCCATTAGTGGGAAGATTTGGTTTTGTGGCATCATGATTATGCTGGGACAA +GGAAAGGGTACACTCAAACAGACACTAGTCAGATTTAACACATGATGGATGAAAGGAGCC +ACTTGTAAAGTCAGCTCAATCAAAGGACCGTCTGTCCATAGCGATACTGCAAGGGGCTAA +GGTATTCTTTCCCCAAGAGTCTGGTGTGAGGGGAGGCTGGGCTGCAGCATGCAGGTGGCA +GCATTTCACTCCGCTGCAATGAAACTGGCAGGTGAGGCCTGCTAGGGTGCCAGCAAAGGA +TCCCCCACAGGCCTCAGACAGGACTGGGGGCCTGAGAGTCCTAGAGACAAAAGGTCACAA +CTCCAGTCCATCTTCTACCTCTGTTCTGATTCTGGGATCACAGGCAGCCTTCAGAGCTGT +CACTGCATCTCCTGGTGGAAGGAACAAGAGGAAGGACATGGAAGGGGAGAATGAAGTGTG +TGCTGAAGAAAGAGCAAGCAGGAGGAAAGGGCTGGATGGGAGTGGGGAGCAGCGTGTAGA +AAGCTGACAAAGGTGGGCTGCGCTCAAGGCCCCCAAGCACAAACGCAGCCCACGAGGCTC +TCCAACCCCAAGCCCCTGTCTACCTTCCAGCCTCAGCACCCAACACAGCCATTGTTTCAT +GTAAAAATGAAACTAGTGGCTAGTTTCACTTGCCATTCAAGGGATCCCACATGTGCTTTT +CCTTGCTTTTCCTTGAGTCAGGTGCTATACTTTGGTTTGCCGCAGAAGTACTTTATGAGC +ATTTCTATTTTGTTACACAGAATATTAAAGAGATCCGTACTCAGGGTTGGAATTCAATAA +AACTGACAATTTTTGCTACTTCATCAAAGACATTCTTGTGTGAAAATGGCATTAAAAAAA +AGCTGGGTGTGATGGCTCATGCCTGTAATCCCAGCACTTTGCGAGGCTGAGGTGGGCAGA +CCACCTGAGTTCAGGAGTTCGAGCCCAGCCTGGCCAACATGGCAAAACTCTGTCTCTATT +AAAAATACAAAAATTAGCTGGTTGTGGTGGCAGGTGTCTCTAATCTCAGTTACTCAGGAG +ACTGAAGCAGGAGAATCACTTGAACCCGGGAGGCGGAGGTTGCAGTGAGCCGAGGTCATG +CTGTTGTAGTCCAGCCTGGGTGACAAAGTGAGACTCTATCTCAAAATAAAAACAAAAACA +AAAACCTGGGAGTACATAGCAGTGGAGAATATAGTGGCTACTGGCACAGTTCAGCATCAC +CACCTTGACCAAGGCACCAACAGTCTTACTCATTGTTGCTTTCCAGCAACAGACAGCATC +TTAGTACGATTACAAAAATCATTTTAACTGTGCAGATTCCTAAAGGAGTTTTGGGGACCC +CCATGGTCTGCAGTGTATGCTGCGAACCACTGGCCTAGGTGATGGGGAGGGACTGGGTGT +GACTGGAGCTGTGCCTGGGGGCCACGGAACTGACTGTGATGTGAAGAACAAACTGGAGGC +TAGAGCAAGAGGGCTGAAAGAGGCTGCTGGAACAGCCCGGGGCAGGGTGAGAAAGGCCTA +CAACAGAGACAGGGAGAGCAGGGAGAGCAAGGAAGAGGAGGTGAGGTGTGTAACAGAGTG +AGGGAATGAAGTCATCGAGGCAGAACTGGTTCTAGTCCTACCAAATGACTGAAGAAGGTG +GGGGCAAAGACCACAGCCCTCCTTGAAGGAAGGGACAGTGTTTAATTCCTCTGTATCCCC +ACTGCCTAGCATGCAGCCAGGAAGAGGAGGGCCTCATATACTTATGATTACATGTTTATT +AACCAAAGTCAGGTCACCATAACAACAGTAGGACCATCAAACAGGGGGAAAATTCAGGAA +GTGGAGCTGGCTGGGGACGGGGAGCAGGGAAAGACAATGGCACCACCGGGGACCTTCAGA +TGAAGAAGGGTGACACACAGCCACCAGGGACTATGAAAACTCACCGATCAGGCTAAAACC +ACTCTCACTCAGCCCTCATCTGACCCAAATCTGCAAATGAGGCATTATTCATAATCTCCC +AGGCATGACAAAACCTCTGGTGACAGTGTAACACAGAACACTTCAAAATGTCATCATATA +TATCATATATACGTTAAAAAAAACCTGAAAAGACACATCTCAAATTATTATTATGTTTTG +AGCTACGGTCTCGCTCTGTCATCCAGGCTGGAGTGCAGTGGCACAATCTCGGCTCACTGC +AGCCTCCGCCTCCCGGGTTCAAGCAATCCTCTTGCCTCAGCCTCCCAAGTAGCTGGCACT +ACAGGCGTGTACCACCATGCTTGGCCAGTTTTTAAATTCTTTGTAGAGACAGTCTTGCTA +TGTTGCCCAGGCTGGCCAAATTATTAGCAATGGTTATTTGGGGAGGGACAGTGTCTAATT +CCTCTCTATCCCCGCTGCCTAGTATGGAGCCAGGCAAAGAGGGGCTTCATATACTTCTGC +TGTATTTTATCTTGTTTTGTTATGAAGTAGTTGTTTTAATTTCATAATTAAATAGATCTG +GCCAGGCGCAGTGGCTCATGCCTGTAATCCCAGCACTTTGAGAGGCCAAGGCAGGCAGAT +CACTTGAGGTCAGGAGTTTGAGGCCAGCCTGGCTAACATGATGAAACCCGTCTCTACTAA +AAACAAAAATTAGCTGGGTGTGGTGGTGCACGCCTGTAATCCCAGCTACTCAGGAAGCTG +AGGCAGGAGAATCGCTTGAACCTGGGAGGCAGAGGTTGCCGTGAGCGGAGATTGCACCAC +TGCACTCCAGCCTGGGCGACAGAGGGAGACTCTATCTGAAAAAAAAAAAAAAAAAAAAGT +AAATAAATATGTTTTAGTTACATGTTTTCCTTATGACCCTTCCATGTCATTCTGTAGAAA +TGTGTTCCTCCTACTAAGCGTTATCTGAGTCGTACCAGGGCAGCTCCGCTATTCCTAGCT +AACTAACTAAGTGCTGAAAACCACGGTCTCTTACCCGCCCTTTCCTCTGGATGTATCAGA +TCATTTCAATTTGAAGTAATCTAAAAGGATAACTAAAATGTACACCCAATCTTACCTATA +GGTTTTTCCAACTTTTGAGAAGATACCATCTGTAAACTTGAAATCCCAAATGAAATAAAG +CTCCTGTCAGGAAGTTGGTGTCTTCCAGCTACACGAAGTGTCTCAATGGCCTTTGTGCGT +AGGTGGCAATCTTCAGTTCTCCATTGGCCTCTGACATGGAAACCTTGAAAAAGCAGAAAT +AGAAAGGAAATCAAAATGCTGACTTCTTTAAAAGGACCAGAAAAGAGAAAGATCAATCTG +AACGTGCCCCAAACCTATGAGTTACCCCACTAAGTAGATATACACGCAGCAATCACAGGT +TTCCCATCTTTAAAATCAGACATTTGAATTAAATTTTTTGTAGAGATAGAGTCTTGTTAT +GTTGCCCAGGCTGGCCAAATTATTAGCAATGATTATTTGGGAAGGGGTGGCTTCTAATTC +CTCTCTATCCCCACTGCCATTAAGCACTGGAAGATTTAACAAAGGTCTGAGTGAAATTTT +TCAGATTCTGTTTCCATTATGGGATTCCAGACCCAAAAAGATGTAACTGGACCTGGATGA +TAGAGATAAGACACCTCTGCTCTGAGGAGTCTCAGGCAAAAGATAAAAGTTGACAGGCCA +GGTGTGGTGGCTCATGCCTGTAATCTCAGCACTTTGGGAGGCTGAGGCAGGTGGATTGAC +TGAGCTCAGAAGTTCAAGACCAGCCTGGGCAACATGGTGAAACCCATCCCTACAAAAATA +CTAAAATTAGCCAGGCATGGTGGCACACACCTGTAGCTGCTTGGGAGGCTGAGGTGGGAG +GATTGCTTGAGCCCAGGAGGTCGAGGCTGCAATGACCCAAGATCATGCCACTGCACTCCA +ACCTGGGTGACAGAGCGAGGCACTCCTCTGCTATCCACGTTTTTAGAGAAATGAGCTGGG +CTCTCTCTCTTAGTGGCCAAGTCCAAGTCTCACAGGCAAGAGGAAACAGAGCCCGAAAGA +TAAAGTAGATGCTGAGAGCAGGAGGTGGCATGAATGGGAACAAGGTTTTGTGTCGAATAC +ATAATTATTGCTAGTTTTCAATCTGATGACTTCATTTTCTCTATGTTCACTGTTATTTTA +ATACCATGGCTCTAGCTATACAAGTCAAAGTTGCTTTGTCAACTTCCCTATGAAATAAAT +ATGCATTTCCCCTTTTCTCGGTGGAAAAGCCCTGAAAATGCAGTTTAACTCTGAATTCTG +AGCCAAAATTTCTAAAAAGGCTTTCTAACTGGAAGTTGGGTGTGTTTCACCATGACCTCA +AACCACATGCCCCAAGTGGGACTTGTGCCCAACCCCCACCCACTGCCTCCTTCCTCTGAC +TTCTCTTCTTCCCTATCAGATCACGTCATCCTGCCAGTTATTCCTCAAAGGCAAGCACTT +ACCTTTTTCATCTTTGCATTACCAGCATCTAACATAGTATCTGGCAAAAATGGGCTCTAG +TGAATCTGAATGAATTACTTAATACACGAAATATCTCTTTAACATCCAATAAAGATGTTA +GCACATTGGACAGTCCTTCCTACTATGCTCTTTATTCCCAAACAAATCTGAAACCCAGTA +AAACTGTTTCCAGGGCCTAAGGAAACTCAGGGTATGCTCTCTTTCTTCACTTCTACTACC +ACACTTCCAGGGACAGCCTTGAACACCATCCAACGACAGGATCTGGCTCCATTAGCCAGG +CTGGAGTGCAGTGGCATGATCTTGGCTCACTGCAGCCTCCACCTGCCAGGCTCAAGTGAT +CCTCCCACCTCAGCCTCCCAAGTAGCTGAAACTACAGGCACGAGCCACCACGCCTAATTT +TTGTATTTTTTGTAGACACAGGGTCTCACCATGTTGCCCAGGCTGGTATTGAGCTCCTGA +GCTCACGTGATTTGCCTGTCTCAGCCTCCCAAAGTGCTGGGATTATGGGCGTGAGCCACC +ACGCCTGGCCTTGAGCTTCCATTCTGTCTTTAGTCTTGTCATAGGTTTAGACCCCCACCT +GGTCCCTTCTTGTTACCTATGGTAGGAGTTGGCAATTTTTTTTCTGTAAAGTGCCAGATG +GTAAATATTTTAAGCTTTGTGTGTCACATGATCTTTGTTATGACTCAATTTTGCATTTGT +AGAGAGAAAGCAGTAGACAATATGTAAATCAATGATTGTAGCTATATGTCAATAAAACTT +TATTTTTGGACACTGAAATTTAAATTTCATAGATTTTCATGTGTCATAAAATATTGATCT +TTTCTTGATTTCTCCCCAACCACATAAAAATGTAAAAAGTACATTAGTTTGCATCCACAC +TAAAACAGGCAGTGAGTCAAATATGGCCTGTGGGCCATACTTTGCCAACCCTTGGCCTAC +AGTAGAAAAAAAACCCCTCAGAATTCCTTATGGGCTTTGTGTTATTTTGCCACGTGGAGC +CACCTTAGGCTGGGGAAGTAGAAAGCACAGGGCTTTTGGGCATTAGGTCCTAGGTTCCAG +TTCTGGCCCTACCATCTACCAGCCGGGTAGCCTTGGACATAAAATTCAAACTCTCTGAGC +TTTACTACCATCATCTATAAAATGGGGCAATAACACCTAGATCACAGAGTTGTCATGGCA +ATTAAGTGAGCTAATGTATATAGAGCTCGTGGCACCAGTATCTGGCATACAGTAGGCACT +CAATAGTAACTCTTATTCCAGCTTCTGACATGGCTTCTCCAGATCAACTGCAGCTCTGGA +AAGCAACCCAGCCAATCTGTGAACCACAGTTGGCCGCAGGAGGGAATAAACTGACAGCAA +ATACAAAGGCAGAGAGAGAATGTGGAGGTTTTCAGATACATGTCACAGGATTCTAAGTGC +CTGGTTAGCCCTAATTCCTTCTGGCACCATTTAAAATTCCTCTGGTCCCTTTTTCCTCCT +CAAAAATTACTTCTGACTCTCACAGTTCTTAAAGATTCTTAGCATTCTTTACCAACTACC +CAGATGGACCCTGGAGCCCTCTCCTCATTCCTGTACCTCCTGCTGGTATAGGGCTGGGGT +GGGGAAGGGTGACCATGGCCAGACCAAACCTACACAGATCCATCGGCCTGCAGCTGGGTC +TTAAGTAGGCTGGGCCTGGCGAGGCACCCAATTCTCTCTCAATTGTTCATGAATTTCTTG +CTGTACTGGGAATTAAATTTCTTCAGTGCTTAAGAACTAGACCTTCTACAGACGTTTTAG +AGCAAAAAAAAAAAAAAAAATCACCATGTATACAAACAAAAGATCCATCACATTACTTTC +AAGACAGAAAACATCAGTGAGGCACAGGTAAGGCTAAGGTTTATGGCATCTCTACCCTTG +GTCCAAAAAGCCAGATCTCGACCTGTTACTTCCTTGCTCTAAAACTTCTAATGGGTGTCC +ACTGCCTCTGGAGTAACCAAGCTTCTGTGCTGTCACTCACGGCCTCCATCAACTTGTCCC +AGACCAACCCTCTATGGGAGTCTTAACCTGCAGTCTCGTCAAAAGGGACTGTATTTCCAC +CTGATTGCTCTAACCAATTCCCAGCTTCCTACACTTGTGCATAATTAAATTACCTGTAAC +ATTTTATTACGCATCTTCCCCTAGACTGTTAGCCAGGGACAGGGTAGAGACTATGTCTCC +TTCATCTCTGGGACCCCTACACCTAGCAGAGGCTCTGGTATGGGGCAACCACTTCATAAT +TGTTAATGAATGGATGGAAACAGCTGAAGTTATTCTTCCCTTAAGCTGTTTTAGCTGGAC +TCTTATTAGAAGACCGAGTACAGTCTGGGTCACTGCCACAAAGCAGAAAAACCGAAGAGA +AAGAAAAGAGGCATGACCAATGTGATCCAAGCAATGGAAAACAGGTTTTAAGAGTGAGGT +TAAAGAGACCAAGGCTGTTTAGCCGGGAGAAGAGAAGATGAGGTTTAACTGGATTCTGGC +TTTAAGTACAGAAAAGGTTCTCATGAGAAAATCTTGATCTCATCCTCCCTTTAAAATCAG +AAGAAACTTTTCCATATTCATGGAAAATGGAACAAGAAGAAATGGCTTAAGTTAAGGCCT +GAAGGGTTTAAGCTGGACAGAAAGAAGAACCAAATTAGGCACCACTTTTCCAGAGATACT +GTTATTGTACTTTTGGCAAGTGAATTGGAGGAGTCTTGCTTGGCACTCTTGTTGAAGGCT +GTGAAAAAAGTAATATATGTGCTGCTCTGTTCCTGTTTACTGTGGAGAGAGGTGAAAACA +CAAGTCAGGTAAGATTTTCTAACGAGCCACTGATTTTTATTGACCCATTTCCTACAGGCA +CTTTCTGCCATGTTATGCATTGCAACCATGTGCTGGAACAATCTAGTATCTCAAAGGTTC +CTGACAGGGCAATGGAAAGAAAGAGAAGGTAACAATGCGGGGGAAGGGAAAATGGCCCTA +ATAAATATACTTTCTATAAAAACAGTACCAAACTGGGCATTCATATATTTATTAATATTA +TTACTATTAAAGCTCACATTCATTGAGCACCTACTGTGTGCCAGGCACTGTGCTGTTGTA +TCTCAATTCTCATAACAACCCCATGAGGTAAGTAATATTTGTATTCTCATTTTACAGATG +AAGGAACAGAAACTCAGGAAGATTAAATAACTTGCCCAAGTCACACAGGTAGCAAGTGAC +AGAGCCAGGACTCAAACCCAGATAGCCTGACTCTAGAGTCCACATACCTAACTACTGTCT +CTCTGTAAGGATGAGAGGCTGGAATATAAACTCTAGTCTCTCTGAATCCTGTTTATATTC +TCAGTTCTTCCTCATACAGTCCCAAGCCAGGACATTAGCAAGAGTTGAGGCCTCAGAAGT +GAACCAAAATACTCCTCTGATTATCAGCATCTATAAAATGGGGGCAATTACACCCACATC +ACAGAGTTGTCATGAGAATTAAGTGAGCTAATGTATATGGAGCTCATGGCATCAGTGCCT +GGCATACAGTAGGCACCCAATAACTAGTAACTGTTATTCCCGCTTCTGATATGGCTTCCC +CAGATCAGCTGTGGCTCTGGAAAGCAACCCAACGACTCTGTGAACCATAACTGGCTGCAG +GAGGGAATAATCTGACAGCAAATACAAAGGAAAGAAACAGACTGAGGACTCTCAGATGAT +AATGAGCAGGTGCAGGACTTGAATGCCAGCCTCTGCACTCCAAGTTAGTGCTCTGTCCTA +CTTACAGACTCTTGTTGAATTTGAGGGTGAGAAAATGAAGAGACAGGATGTGCCAAACAG +GCTGCCTCCCCCGACAGACCCTTTTGTAACGTCAATCTCCCATCAGAACCCATGCCTGAA +ATACCAGGGTCCTGCAGCTTCTGTAAACTGGTTCTAAGATTCTACTAGCTAAGGATGGCA +ATGCACTGATTTATGGCACTGTGGGTGCTGCCAAAATGATCACCTATTAAACCTATCAAG +CAGACCTAGTCCATGCAGCTTCCAAACTAGGCCAGTGATTCACCGTTTAAGCCTCTTCAC +TGATGTCCCCATTCTGGGACCATCTTTGCTCCAGTCTAACCTCCGTCCTGCTGCCAGAGA +AAACCGAGCGCCAGTCAGGGCATTTGGAGCCTCTAGCATAAGGAAGATAACATGGGCCTT +TGAACTCAGCACTGCTAGTTTTGAACCAAGCTGTGCCCTTACTATCTATCTAACCTTGGG +GAAGTCACTTTAATCTTTCTGAGGTCTGGTTTCCTCATCTTTAGATTGGAGATAAATAGG +CCTATATTACAGGATTAAATATAGTATGTAAAGCAACCAGCATACTGCAAGCCACAAAGC +AAAGGAGACACTTTATAAATGCTAGTGTTCTGCTCCCTACTCCACTCTCTACATTTTAGC +CAAAATCTGCCAATTCGGCTTACTTCTTCTCCTCACCAACTCCTCTCCCCTCCCACAACA +CACACACACACACCCCTACACCTGAGCATTTCTGCCTCTCAACTGTTGCTCAAGCTGTTC +CTTCTCCCAGGAATAAACTCCCTCCAAGGCCCAGCATAAATTCTCCACCTTCAGGAATCC +TCTGGTCATGCTGGGATTGATTTCTCCTTCTTCCAAACTCCCACTTTGTTTACATTCCTT +ACTACATTTACCATAGTCAGTCTGATTTCAGTTATTTATGTACTTATCTATCTTCCCAAC +TACACTGGAGGGAGAAGGTTCTGAGAAGACAATTATTTATAGGAGGGCAGGAAATGTGTT +GTTTTCCTCTGTGTATATTTCTCAATACCAGGGTCTTGTACATAGCAAGAGCTCAATATG +TGCTTACCGAATTGAATCTTTCCATCCTATACTGGGAATCTTTACAGAAAGATCCCAGAC +TGAGTTCATTCTAAAACTGCATTTACTGCCTAACTTGATAAATAGGCAATTTTTGAAGTA +CATGAATATTCCTAAACTAAGATCCGCTAATACTCATGTGGGCTTGTTTCATTCCTTCAT +CCATTCTTCCAATACACTCTGGACTCTTCTTGGGATCTCTCTCCAGCATATAAGGAGACA +TTGCTGGGACAACACTTCTCACTCACGGAGATCTGGGAGCAAGCTCTTTGGAGAACTGTT +CCACCCCACTGGGTAGGAGGTGACTGCCATTAAAACCACACTAAAACCCAGAGTTGTGGA +ATTGGAAAATAGATCTGAATGATCTGCCTTAGTTTCCAAGCTATAACACAGAGTTAAAAA +CACTTTTAAAAACAGTGTCTGGAACACAGCAAGTGTGCAATAAATGTTCGATGTTGTATT +AACAACGTAGTAGACTGAAAAAACAGAGTCATGACATTTCACTTCTAGAACTATCTCCAC +TACTGACTGATTCCTTGTGTAATCTTTTTTTTTTTTTGAGACAGAGTCTCACTCTGTCGC +CCAGGCTGGAGTGCAATGGCACAATTTCAGCTCACTGCAACCTCTGCCTTCTGGGTTCAA +GCGATTCTCCTGCCTCAGCCTCCCAAATAGTTGGGATTACAGGCACCCACCACCATGCAC +AGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCACCATGTTGGTCAGGCTGGTCTCG +AACTTCTGACCTCAGGTGATCCACCTGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCG +TGAGCCACACACCGGCCTCCTTGTGTAATCTCAATCAAGTCCTTTCCCCATCTATAAAAT +GAAAGTGGCGGAACCAGATGGTTGGTTTCCAAGCTCCTTCTACCTTCAACCATGTAAATT +TTTCTCTGATCAAGAAATAACTTTCTCTTCCACATGCTGAGGCTGTTGGCAAGGGAAAAT +GTGCATTTATAGCTGCTGGTCCCCAGATGGGAGGAACCACTGTTTCCCAAGGCCAAGGGC +AGAGTAAACTGATTAGAAAACCACCTGTGAGCTTTCCCCTGTTTGAACTGTACTATTAAT +ACACCCAGTGCAGGTCTCTGAACACAGCATTACCTACCTTCCAACAAAACTCACGGTCAA +GGCAAGACAAGAGCCTGAAAACAATGGCTGCAATGAAGAATGCCTGCTTGTGCAGAATTC +TTGTACTTTCTTGTTTTTGATGCCTGTAATTAGGGCATCAGTCTAAACTGGGGCCCTCCT +TAGGCACAAAGAGGAGGAAAAACACAAAGTCCCATTCTGAACCTGACAGCTCATAAAACA +AGGGCCAAACCTAGTAAATAAAAAATGTCACTGACTCACTTAACCACAAACACTGAAGAG +GCCTACTATGTGCTGGCCCTATGCTGGACAGAGGAGGAAGGAAAGAGACATGGTCCCTTG +CCACCCACGTACTCAGAGTACATATGGAGTGTACATATCCCTAGGCAGACAATGATGAGA +GCTATATTAGAGGGTCAGCCTTTGCTACAGAAGATGGAAAGGGGAACAACTAATCCAGCA +GAAGGCTCAGAAAAGCTTCACCATGGAGGCCACATGAGATGTAAGAGATGTAAGCCTTGA +AAGATGAGGAGGAGGAGGGAAATCCAGGAAGAGAGAATATAAGCAAAGGCTCGAGCAGGA +ACATGCAGGGAGTGTTTGAGAAACAGAGATTTGGCCGGGCACGTTGGCTCACATCTGTAG +TACCAGCACTTTGGGAGGCCCAGGCAGGCGGATCACCTGAGGTCAGAAGTTTGAATCCAG +CCTGGCCAACATGGCGAAACCCCGTCTCTACTAAAAATACAAAAATTAGCCGGGTGTGGT +GGCTCATGCCTGTAATTCCAGCTACTCAGGAGGCTGAGGCAGGAGAATCACTTGAACCTG +GGAAGTGGAGGTTGCAGTGAGCCGAGATTGTGCCACTGCACTCCAGCCTGGGTGACAAAG +TGAGACTCCATCTCAAAAAAAAAGGAGAAACAGAGACAACTAGTTTATTTTGACTGAAGC +ACAGGTTGCAGGTTTGGGAAAACCAAGGGAAACAGGGAGGGGAGAGGTGTGGGAACAAAT +TGTGCAGGAACTTGTCTGAGGCTGGAGTCCAAACTCTACATCCAGCTTGTCCAACCCGCG +GCCCTGGATGGCTCTGAATGTGGTCCAACACAAATTCATAAACGTTCTTAAAACACTGAG +ATTTTTTTGCAATTTTTTTAAAGCTCATCAGCTATTGTTAATGTTAGTGTATTTTATGTG +TGGCCCAAGATGGTTCTTCTTCTTCCAATGTGGCCCAGGGAAGCCAAAAGATTGGACACC +ACTGCTCTATATAGTAGGCAATGATGCCCACCAAGGTTTCCGAGTAGTGTCTCAGGAAGA +GCACAAGGGCACCCATGAAGAGGATGCAAAAGGAACTAAGTAATTCAATTACTCTGGGAC +CACATTACAGGAGACCACATGCACTTTCTAAGCACGTGCTGGGCTCTGACAGCTCCTGTT +CACAGAGCTTCCCTCTCCCATGGCTTCGCTTCATGCAATCTGAGTTGCCATCCCCCACAA +CTGTCAACATCTGCAAAATACCAGAGTAACAGGACTCCTAACCAACTCTCTGGATTACAG +AGAGAGAAGTGTTGAGGTGGGAGCAGATGGGCAGAGGGGGCACCAAAGCCTCTAGCTGGC +TCAGTTCCATATAAAACCCAACCCTGGATTTCCTCTTCACATCACTTCCAGCCCAGCCCT +CTAATGAAGGGCTGAAGCTAAGGAGAGTGGGCTGAAAGCACCTGGCTGATGGGTGGTGAT +CCAGTGAGACATTACACCTACTGTCCAGCATGTGCCTGGCGCATGGGCAGTGGTGCCCTT +CCCATTCTGCAGGGTCAGTTCCATCTGTAAATCCCACTGAGGCTTCAAGGCCCAGGTCAC +AACAACTCTTCTCTCAGAGCCTTTCTAAAGTACCCCAATCCAAAATGACCAAGCTCCTAG +AAATCACAGCTACCATGTATTCAGCACCCATTACATGACAGGCGCCATACTAGGTGACTT +CCATATAATCCTATTCACCCTTCACAATGACCCTATTATGGCCATTTCCTAGGGAAGAAA +GTGAAGCTCTGGGAGGGGAAGCAGACTTGCCCCAGGACACACAGCTAAGAGGTGGAAGAG +ATGAGATCTAAACCCAGGACTCCCTGACCCTGAAGTTGAGCACTTCTAACAACACTTCAT +TCCTGTGAGCCTGCCTGCCTCTGATCTGCCACTGTCAGGGAGCTTGGAGCTCTCTAGAAG +ACAGGGTGCACCTGACACTCTTATTACCTTTCCCTGTGGACAGCCATCCACACAGGCAGG +AGCCTTTAAATACTGAAAATAAATGAAAACAATTAACTTAAAAATAACGCAGTACACAGA +TTTCACAAATTCCTCACGTGAAAAACTATTCATGATACTGGACTGCCTGAGCCCTGCGCC +CAGCCATAGCCTCGGTCCTGATCCCTGGGAGAGACTGAGTCTCAAACGGGCCACAGAGTA +AGCGCCATCTCGGACACCGGCCACGCCCCGACCCCAGGCACAGAGGTCGCAGACAGCTCG +GGACAGTCCTGAAAAGCGTCCCCTTAGGCTGTCCCTCCGCAGCTGAATCGCGTCGTGACC +TCGGGCAGCCGTGAAGGCCCTGACTGCCCCCTTCCGGGCACACGAGCTCACTCACAGACC +CCGGCCCCATTTAGCTCGGAGGAATACCTCGCAGGTCTCGCTTTTACCTTCGCTGGCTCC +CGCCGGGGAGCGGTCGCGCGCACCCCTACCTGCAGATCGCTCCTCCGAGAACGCGGAAGA +GGCGGTGCTAGATCCAGGGGGTGGGCCCGATCAGAGAGGAGGGTGAGGGGGCGGAGCTGC +GCCTGCGCCCTGATGGCTACCCAGGGCCGCCTGAGGGCAGGGGGCTCGAGCTGAGCGAAC +TGCGCAGGCGTGACAGGGAAGAGGCGGGGAGAGGGGAGATTGCTGGCAAGCGGGTGGGGC +TTAGCTCCTCCGGCGCTTTCTTTTCCGAATGGAGGGTGGAGAAGCCCGGGAAGGTAGGAG +GCCGGGCGCGACAGGTGTAATTAACATGTACTGAGAGCTTCTGCAGGCCAGGAAGGAATT +TTAAAATGCCTTTTATATGTGGGGAAATGCTGCTAGTCTTTTCTAAAACGGGGGCCAATT +CTGTACAATTTCTTTAAAAGTCTGAGTGCCTAGAATTTCACCATAAGAGTTTCTCCTTGA +GTACAACATTATCCCCAGTATTTCAAAATTTTTAAAACTTTTAAAAGTTCATTTCTTGGG +GAAAAACAACTGTAAATAGGTTAATGCCTCAACCAGTCTCCCCACATCCCCTTCCCAAGT +CTGCAGCTGCGATGAGAAAGGATGAGAGTGTGGACTGGGATTTAATTCAGGCGCTGACTC +CGAGTGATGGAGGTGAACATCCCTTCCCTGCCTGTCTCAGGATTATCGTGAGGATTTGGT +AAGCCAAGCTAGTTAAAGAGCCCCAGGGACTTGCTTCCCATCATCCACCTGACAAACATT +TGTTCCCTGTCTTGTCGGGGCTGTCTTTTCATCTGTATGATGGAAGGAGATTGGGAATAT +TAGTGAACATTCAGGACTTTGCTAGATTTCCCAATCTGGGTGAAGGCCGGAGAGGCGGAA +GATCAAGCTTCTGTGTTCATTCCCTTCTGGAATCCTGCGGTCCAACCTGAGGGCCCCGAT +GTATCCTGACTTCTCCCACTCATTACCTTCCGTGGAGGCCGATCCAAGCTTCAAGTCTTC +AGAGGCCCTGCTGGCCTGTTCCCTTCCCTGTTGCCTGTGGCAATAGCCCAAGAGATTCAG +GACCTATGTTCCAGGTTCTCAAAGTTGCTATGTCCCTCACATGGCAATCAAATTCAGTTA +ACATCTTTGAGGGCTCTGGGGGTGCTCAGAGGAAGGAGGGCTCCCCCAAAGCAGGTGGAG +CTCTAGTCATGACTGTGGCTTATTTCACCACATATTCCACAGCTTGCTGTGGGGTAGGGA +GGAGAGGCAACAGGAAACCTCAGAGGCTGCAGTGTTTATGGGAGCCGAGGGTGATGCGGC +ATCCTTTACTCAATAGGTGGATGCTCTGCCCCAGGCTGGAGAGGATGGCTTACTACCTAG +GTCCCTGCTCCAAATATTGTTTTGGAATTTTTTTTCTTTTTTTTTTTCTGAGACAAGGTC +TCACTGTGTTCCCCAGGCTGGAGTGCAGTGGCACCAGCTTTGCTCACTGCAACCTCTGCT +TGGGCTCAAGTGATCCTCCTGCTTCAGCCTCCTGAGTAGCTGGGATTACAGGCATGCACT +ACCATGACTGGCTAATTTTTGAATTTTTTTAGAGGCAGGGTTTTGCCATGTTGCCCAGGC +TGGTCTCGAACTCCTGAGCTCAATGATCCTCCCACCTTGGCCTCCCAAAGTGCTGGGATT +ACAGGGAAGAGCCACTATGCCCAGCTTTGTTATGGACCTTGAGCCAACAGGAAAATAAAG +CCCAGCCTGACTTCTCAACCAAGCTGCCACTCTACCTCCCAGGACCCTTTGTTACTAGGT +TTTGCCCCATGGGAGTGTGCTCTTTTATCTGCATCATTGAGGCCCTATCTCTTTCTTTTC +CCCTTCTCTTCCTTTCTGTCTATTCTTCTTTAAGCATCCCTCTGTGAATCTCTCAAAGCA +ATTTTGTGTCAGCTTCCTAATGTATTTACAGATATTCTCATGTAAGGTGCAGGTCTTGGG +TCACACAGTTCTAAGATAAATCTACTCTCACTGCCATGGTCATATTTCAAAATGACCATG +AACCCAAAGCATGGGACTTGTAACAGTCTGAGCTGTCCAATGACAGAGGAGGTAGTGAGC +GATCTGTTATAGGAGGTGTGCAAATAGCACCCTTTTAGAATGCTGGGATTGGGCCTCCTG +TGGTGAGCCAGAGGAAGAGGCAGCAGAATGGAGGGCCTTCCAGATTCTAGAGGAGTGACT +AAAGGCAGGGATATTGGGGGCTGGAAGGGAAGCAAGGCAGCTGGCCAAAGACACACTTGA +TTCAACAAGCTATTATATGTCAAGCACTTAGAAGTGTACCTGACACATAATGAACATTAG +CTGTTATGATGACTGTGAATGATTCATAGACTATATAATGAAGGAGCTGAGATCAATCAG +TCCTTCACTCCCATCACTGATAACAAAATAGATGAAGGGTTGGGGTCTAGAGGGGGAATG +GGCTTGCAATGGAACTTCAGGAGCTGGGCTGGGGCTACAACCTATGCCTTTGCCTCCCAG +GAGAGCCTCTGCACAAAGCCAGGCTGGCTCCTTTGCAGGAAGAGGGAAGAGCTCTAGATG +GGCCTTTGTTGACTCTTAAGAACCAAGCTGCTTTTTAATTCCTGCCCAGGCAGCTTGTGA +GTTGGGGCAGTGGAATGACAGCAAGACCTGAGCCAATAGATGCAGATGTCTACTGGGGAG +TAAGCTCAGGAGTCAGGCCCATGTCCTGCCACCCCCACCGTAGCTCCAGCCAGCAACAAG +TATCTTCCTCTTCAGGATGGCCTCCTGTCCTGTAATTAGTGTTGGGATTGTATTTCCACT +CTGTCCTTTTATCTACTACCTCAAAAAAAAACCACCCAGAGTAAGGGGCTGGAGTGAGAA +TAGCCAATGCCAGGCCAGGCGTGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCC +GAGGCGGGTAGATCACGAGGTCAGGAGATCGAGACCATCCTGGCTAACGCGGTGAAACCC +CGTTTCTACTAAAAATACAAAAAAATTAGCTGGGCGTGGTGGTGGGTGCCTGTAGTCCCA +GCTACTCCGGAGGCTGAGGCAGGAGAATGGCATGAACCCAGGAGGCGGAGCTTGCAGTGA +GCCAAGATCGCGCCACTGCACTCCAACCTGGGTGACAGAGCAAGACTCCATCTCAAAAAA +AAAAAAAAAAAGAAAAAGAAAAAAAAGAATAGCCAATGCCAGGCAACCTGAGATGAAACA +AGGAACGATTCCTATCAGACTGAGTTCCCGGAAGGCAAAGAAAAGCCAGGCTTCTCCACC +CCAAGCGTCCTAGCCTAGCTCGGTCTAGAATTTCCAGAGCCCCAGGAGAATCTTTGTGTC +CCCACCCTAGAGAGCTGGGCCAGACATGACCACACCAGCCAGCCCTCCACATGGTCCAGT +ATCTCAGGACAAAAAGCCTTCCCAGCCCCATTCTGGCTCAGTTCCTTCCATGGTCTGCCA +AGAGCCATGTGGCACCCAGATCACCGCTTCCCACCAGTGGCTGCTTTAGTTTGCCTTTTA +TTTTACCAAAAATAACAACAATAAAGTCTTCCCTCTGTTTCATAAAAATAAATTTTCCAA +CCCTCCCCCTATCCCAGAAATCAGCCCTTGCCACAGCCTAGAATCCATCATGCAAGTCAC +AGCACTCTGGGAAAAGCTCCTACTACCCTCGCTCCACAGCCTCTGGCAAAGCTGCCAGGC +CACTCTGGAGGCGGCAGAGGCAGAAGTCCCAGGCCCAGCTGGCTGGGCCCAAGAGCTCCA +TCTGTTTCCCCAAAGTACAGGCAGCTTCTAGGCCATTGAGTGGGGCATGATATTGGATGC +TTGGCTCAGGAAACAACCCCAGCCAACCCAAGGGGCAGTGGGACATGTTGGCCTCAGGTT +AGAAATTATTGCTCAAAGCAGAAACAGTTGTGTCCTAGAGAGGGTCTGTTAAACCCTCTT +TCCATGTGTATCTCTATGTAGCAATTGATGGGCCCTGCGGTCAGGATCCCTGGTTTCTCC +AGCTCCATGAATGCCTCCCTGTGAGGCCCTGGACAGTTTCTCCCTCTTCTTCTCCTGGCT +TCAGTTTCCCCGTATGTACATTGAGACAGTAAGACTGGATGATTCTCAGGTTCCCTCTGG +CTTTCCATTCTGGCATCCCAGAGTGGAGGCTCTGGGAGGGCAGAACCCTGTTCCTGCCTC +AGTTTCCCCACCTGTGGGTCTGCGTATAGGGCTGGGTATGGAGGTACTGAGTAATGGAGT +GCTGCGTGAACATCCCAGTCTCCCTGTGGATAGCTGTGCTGTGAGATCCAACTGGCTGGA +ATGTGTCAGGGATGGCTGGGAAGGAGGCAGGTACTTTTAGGATGGAGGATCTCCATGCCT +GGAAGAGTCCATTCACCAACTACATCCTCAATGTGCTGGGATGGGAGACAAGACTCCAAA +GTTCCCAATTCAAGTTCCACAAGCTCCTTGGACGGGGAGATTATTTTGTGCTGGGCTTCA +GATCCGAGGAGCCAGGTCTGTAGATTCTGGGAGCTAGAGTGGAGTATATGATTCCCAGAT +GAAGGGCCAGGGGACCTTTGTGTACTTGAGGGATCATCTCCAACCCCCAGGAGGACACGT +ATAATACAGGCCTTCTTGGAGGCAGAGGGATGAGTAAAATGTCAGCTCATGGGCATCTCT +GGGTAAGAGAATCAGAGCCTGTGTCTGCAGTGGGTCGGTTTAGGAACTCAAGGCAAGGCT +CCTCTTCCTACGTTCCCCCAGCTCTCCAGGACTCATGCTGATGGAAGAGTGTAGCCTGGA +AGGTTTGAATGTAGAGCAACATCTACAACCACATTTTTGTGCACTTACACACATGGTCAG +ATACACTGAGTGGGGACGCTGAGCTGTCATCACTCCTACAGTGGTCATGGTCTGATGGTC +CCATGGTCTGATGGTCCCAATCTATTTATCCATCCATCCAACATTTATGGAAGGCCTACT +ATGTGCCAAGGAGGGGTAAGGCAGCTAGCTCTCACAGACACACCCCACAGTGAAAATCAC +ACACACACACACACACCCCGGCATCTGTGCTCACTCACAGGCAGACTGCTCACTTTCTTG +CACCTTTCTTGCCATCACCTCGGCCACACCCACATTCCTCCAATAGGCTTGGGAACCAGC +ATGGAAGGGTCAAGTGTCATAGAAGAAACCCCCTAGCCTACCCTACTCCCAGACTTCATG +CCAGAGGTTTAACTCCACTTCCCTTCTGTTTGCCTGCCTAGATGCTCTCCCCTTCTCCAT +CCACAAGCGGTCAGGGCGACAGGTAGGCAGACTCCTGAGAACCAGAAGTCCAGAGGCTTT +GGGTGTGTGGAGTGATTCCAGTGCCTTCAGATTCCTTCAGGCTCCTGGGGGTCCCCTCTG +CCAGCCACCCTATGTTCAGATCGTCCATCTGATGGCCAAAAAAGTCCAGACCTGGGCTCA +GTGGCAGATCCGCTCTGTCATCTCCCTCTGTAGAGACACAAGGTAGGGAGGGGTCAATTA +GAGCTCAGCCTACTAGGCAATCCCTTCCCAAACCATAGGGCCTAGCTGCTCTTCTGTCTG +AGCCTGGCCTTCCCCCAGCAACCCCAACTCTTAGGCTGCAGATCTGGGTTTGTAAACCAA +CACTTGAATGAATTCTCTATTGAAGTACAGAATTCACTGTTAAATGAATTGCCTTCCCCT +AATTCATCTACTTGGGCGTTGGAGTTACTTAAAGCAGGCAGCTTTTGGACGTGAAAACTC +AGAGGCTAGCCTTGGTAGGGGAGGGTGGTAGGGCTTGGCCTCACCAGTGGCTCCAGCTCC +CGCTGGTCCACCAGACTGAACTCGCGGATGAAGTAGTAGAAGTGCTTGTAGCAGGTGTTG +ACGTGCGCCTCTGCCCCCATGCTGAGGATGCTATCGAAGTGGTGGATGTAGACATGGACA +AAGACTCGGAAGAGGCGGGTCAGGATCTTGGTGCAGACCTGCTGGAAGTTCTTAGGGAAG +GGAACTCCTAGAGGGCAGGGGAGGGCAGAAGGGGATCAGTATCCTGGTGCCAAAGCTCTG +CTCAACTTTTCCCTCCCACACACAGGCAACCAGGATGGCTTTTTCCCCAGCACACTTTTT +AGTACACTTCCCTTTGGAAAACAGAGAGTGGTTTGACTTTCTCCCATACTTTTCTTTCTT +TCTTCCTTTCTTTTTTTCTTTCCTTTTTGAGACGGAGTTTCACTCTTGCCCAGGCAAGTG +CAATGGCATGATCTCGGCTCACTGCAACCTCCACCTCCCAGGTTCAAGGTATTCTCCTGC +CTCAGCCTCCCAAGTAGCTGGGATTACAGACATGTGCCATCATGCCCAGCTAATTTTGTA +TTTTTAGTAGAGACAGGGTTTCTCCATGTTGGTCAGGCTGGTCTTGAACTCCTGACCTCA +GGTGATCCACCTGCCTCGTCCTCCTAAATGCTGGGATTACAGGCATGAGCCACTGTGCCT +GGCCATACTTTTCTTTCTAATGAAGCACAAATCTGACTGTGGCTCTCCCCTGCTGGAATA +TACATCATCTTCCACATTTTCCCATTACCTAAAGCAGGGCTTTGCAAACTTGTGGGGGTC +ACTGACCAACCCTTTTTAGACTATGATAAAAGTTACGACCTAAACTCTCCCCAGAAATAT +GTGCAATTGCAGAGATGCTCACATCACACTCTTGTATACAACTCCAAGGAGAGTTCAACA +ACTGGGTCCATTTAAAAAATCCCTGGGCCTTCAGGATTAAGTCCTAACTTTCCAGCAGGA +CGCTGCTCAAGGCCTTTCATGATCTTATCCTGACCTCCCTCTCTAGCCCCACCCCATGTC +CCTCCTCTTTTCAACATTCACACAGAAGTCCTCAGACCCCCAATCCTGGAAATTATGAAT +TCTGCAAGAGTTAGTTCAGACAGCCCTCATTCCTTCAAATATTCAACAACACGAAGAACC +TTCCATTTATGAGCAAGGCCTTGTGCTGGGCCCTTCACACCTTTTGCCTCTAATCCTTAG +AACAATTCGCCTGATGTGTCTGATTGTCACTTTAGATATGATAAAACAGAAGTGCTTATA +AAGGTGAAGCTGCTAGCCCAAGGCCACATAAGTATTAATCAGTGCAGAATGGAGACTGGA +TTCAGACCCTCTTTGCAGTGCACTGCAGCGACCCTCACAGATATTGGGACCCATGAAAAA +GGCCCCGCTTCTGCATAGTCCCCCATGCTCAAGGCAGAGATCTTGGTGGCTTATGCCCTC +TTCTCTGTGTGGCAGTCACCCAGGGTTTTAGGCATCGATACCTGGAGTCCCACAGGCCCA +GGGAGGTATGGCCAGCAGGGACTATGAATCTACATTCAGGTCCACAGCTGGCCCACCCGG +CTCTGTAGACCCCCTCCTCTTCCTCACCATTCCCAGGTGGGGTCGAGCCTTCCCTCCCTC +TGAGCCCCTCCAGCCCAGCCCAGATTCCTCAGACATATCCTGCCCATGTAGACTTGGGGT +CCTGGGCTCCCACAGATCTGAGCCCCAGTTCGGAATTCCTCCCAGTTCAGTGCACTTTCC +CTCAGTAGCCTCAAGTTTCCTCCTATGTAAAATGAAGGTGCTCCTTGTCGGGCATGACAG +TGCAAGAAACAGCAGGCCACTGGCTGGGGAGGAGCCGTGGGCATTGAATTGTGACTCAGT +GCCCAGCTTCCTTCAGCATTCAGACTTCTCCCCTCAGGGCTTGACCACCCTGCCCCACCC +ACCGCTGATCCACACAGCCTCTGCAGAGATGAGCTCCAGGCCAGGTGGGGGCTGGGCCCA +GCTACAGGTGCGGCTGGTGTGATGAACACAGTGTCATGCCTGCTCAGCTCCTGGACCAAC +AACCCCCTCCTGCTGCCCTCGGGTGGGTAAGCAGTGCCTGGGTGACATCACTCATCTCCC +CTCCCTACCCTCACCCGCCCAGGCTGCCCAGCTGAGATAAGAAAAGGCCCCACAGCCTGT +GCCTGGCAAGGGAAAATTCTGTCCTCAGAGCCCCAATCTGAGGTGATGATACCACCAGGG +CCCACCCAACCACCAACTCCCTCCTTTTCCTGAGGCCAGGAGTCAGAGGGAACCCCGGGA +GGCTGGAGGTCAAATCAGCTATGAACACCTCGGGGCAACTGTTCTGGAAGGTTCTGAGAA +TCACAGCATCTGTGGTCTTGCCAGAGTGGTCCTTGGTGGGACCACTTATGCTTTAGAAAA +GAAAAGCCCTCTGAGGTGGGTGGATCACCTGAGGTCAGGTGTTCGAGATCAGCCTGGCCA +ATGTGGTGAAACCCTGTCTCTACTAAAAATACAAAAATTAGCCAGGCGTGGTGGTGGGTG +CCTATAATCCCAGCTACTCAGAAGGCTGAGGCAGGAGAATCGCTTGAACCCGGGGGGCAG +AGGTTGCAGTAAGCTGAGATCTCACCACTGGGTGAAAGACCGAAACTCTGTCTCAGAAAA +GAAAAAAAAAAAAAAAGAAAGAAAGAAAGAAAAAGAAAAGAAAGAAAAGCCCCAAATTGG +GAGTCAGGAAGTCCTAGCAAATGCTTGACCTTGAGCAAGGCACTTAACCTGTTTCAACCT +CGCTTTCCTCTTCCACAAAATGGGGATGAAAATCAACCCCCAACCCTGCAGAGTGTCTAT +ATCAAACTAAATCCTCATCTGTGGAATGGGCTCCCAGTGGCTCCCTCCCCGCCAGGTGAC +ACTCACCAACACGCGTGGGAAAGACCTCTTCGTCGTTGATGAGGCCTTCGATCCAGTCCA +TGAGCAATGCCATATAGCGCGGCGCAGAGAGCTTGGCGGGCCGCCGGTACTGGCGCTCGT +CCTGCCAGCGGTACTCGTAGCGGGGCCCGCCGGCCATGACCGGGCAGCTGGTCTCACTGC +AGCGCTCCGCCATAGTGCCGTAGATGAGGTTGATGCGGTTGAAGAAGTCCACCACGTGCA +CGGCGATCCAGTCGTCGATGTTCTCCCCGGGTGGTAGCCTCACCACACTGCGCAGGTCCA +GGCCCGACTTGAGAGAGGCCTGTGCCTTCTTGTACAGCTCAAAGCGCTGTGTGCCCGGCT +CAAAGCGCTTCCGCGGCCGGAACGTCTTGTCCTTGGCGAACACCTGCTTCAGGCACAGGG +CCATGGCCAGCTGGGCCTGGGGCTGCTGTCCAGGGGCTCGGACCTGAGGATACCCTGCCA +GGGACAAGGGCATAGGGGAGCTGGCGGTCAAGGCCTTATCATCTGGGCTCTGACTTCCCA +ATTCATCATTTCCCTGTCACCTCTCAGCCTTTGCTCAACCTCTGCATCCTCTGCCTGGAA +TCTAAGTCCTCAGCCCCTAGGTCCAGTGCCCCGCCCTCTTTCCAGGCTATGTTAGTCCCC +CTTGCTAAGCCCCCACAGTCCTCCCATCTTGCTTTGTCTCTTTTCTGCTTTCATTGCAGA +GCTGGGCCTGGGCTCTAAACAGGTGCCCCTCAGACTTGCTGTTGGTCACGAGAGAGGTCG +CAGAGGCTCCCTGCAGGCCCACCAGCAGACAGGGGCTTGGACGAGATGACCTCTGGGAGC +CCCCTTGGCCAGCTGGTGCAACGTGGGAGAGCCTCGCAGCATTGTGCTGGGGGCAGGGTG +GAGGGGGGTCGGGGGTGGCTTTCGGCTTCCTCTGGGATATCCCGTAGTCCATCCGGCCAC +CGGGGATTCCCAGGGAGCAGCAGGGAACTTTTCTACCAAAAATGTCCTTTCCTTTTTTTT +CACCCTGAAAGAGGAAAGGGCCCTCCCGCTGCCAGCTGGGCGGCTTCTGAGTGTGGCTGC +AAGCACTGGAGGAGGGGGAGGGCGGCAGGCCAATGAGGGCGTCGCTTCCTCTGACAACAG +CTGGAGATCCTTCCCCTCAAGCCAGCCTCCTCCAGCCCCAAATCTGAACAAGCCACTGGC +TCCTCCCGTTGCACCTGACACTCAGTAGACATTCCTCTAGCAACTACTATGTGCCTGGCA +CTGGGAGGTAGAAGAGTATAGTCAGATGCACCCAGGAGGGCCCATCTAGAGCTCAGGCAA +ATTTACTTTGCCTCCTAGAATTTAAGGATCCCAGATTCAGAACAAATTTTGGGAGACAGT +GATCAGGGCCCTAGGCTCAGAGGCAGGAGTCCTGGGTTCTAGTCCCAGCTCTACCACTGG +CTTACTGGGTGACCCCTGTATCACCATGGATTTAGCCCATCCAGGTCCTGGGTCACTCTG +CTATAGCTAGGTTTCTAAGACCTGAGTCATCTCATCTCAACTGTGAGTGTGTGAGCTACT +GGGAAATGCAGACCCATGTACCTACCAAAACTAGAATTTAGCCACCCACTAAGCACACTG +CCCCTGCCCCTAGACTGAGCACTAAGGCTGAGTATAAGCTAAGAATTGCATTCTGGTTCC +TGGCTGACCTCTGACCTGGGCTCTGGCAAGTGTGAGCCCTGACTCTAGCCTTTAGCCCTA +CCCTGAGGCTTGCTTATGGCCAAAGCCTGGGCTTGACCTCTGACGCTGGAGCACTGTCCT +TTCTCACATCTCTGGTAACCCTGGGACAGGATTGGGGAAGGGAGGGTGGGAACCAGGTGA +CACCTGGGTAAAAGCAAAGGGATGGCACATATTTCGGGGAGGGGTATTACTTCTGGCAAG +AAGTCAAACTAGCTGGGGAGCTGTTTGAGACAAAGGTCCTTCCTTGAACCCACAAAGGCA +GGCCAGGATGGGGGCAGTCTGGTAAAATGAGAGCAGCTTGGAGAGTAGAAACAGGCCATT +CAGCAGGAACTTGTTCTCTTGAAAAAAACTCACAGATGTGAAAGGTCATCTCATCCATCC +CGACTCTTCGACTTCTCACCCAAAGAAGTCCCCAGGGTGGGACCCCAGTTTCCAGAGCAA +AGAGATTTCTGCGCTTCATTTGCCATCTCCATTTTAAACTCTGCTTGGGGCAAGTGCTTC +CAAAATCCCTCACACTGCAATTAGGCGGGGCTCCTGGGCTCCCCACATTGCATGGCCCCC +TTTATGACAGTTAGAAATAGGCCCCCACCCTGGCATTCAGCACCTTGTCCTACCTTTCCT +GCCCCACTTCCCACCTCCCCACACCAACCACCCTGGGCTTCTTCCTGATTCCTGAACACG +CCCCCACTCTTTTGCCTCTGCATGTTTTCTTATCCCTCCACCTGCCTGACCACACATCCT +CAGATTGGCTGCTACCTCCTCCCACAGCCTCCTCTCCTGAACTCAGATCTCCTTCTCCTT +GGGTAGAGGCTGCTTTTGGTCATTGCAGTCTCCACTCCATCCCCAACCCACCCCCAGCTT +AGGACAAGGCCTGGCACAAAGTCAGTGTTCAGGCTTTAAGGAAAGCTTAGACTAGAATCT +TAGAGTTAAAATAGCCCTGATAGATCAGCTGGCCCAACTCACTTGTACAGATGGGGAAAC +TGAGGCCCAGATGAGGAAACTGAGGCCTAAAAAGAGGACTTGAGGAGCCTGTGTCCACAT +AGCAAGTTACAAGCAGAACTGGGAACTGGGATAAGGTGGGGCTCAGCTCATGACCAAGAG +TAAAAGACCATTTTCCTGCACTGGCTCATCAATGGTCTGGTGGAGACAGAGAAGAGGAGG +GGAGTGGAGGGACAGTGGAAGCATCTTCTCCACCAAACAGCCCAACCTGCTTCCTGTCCC +CAACACACTGACTCCGCACAGCAACTGGGGTGTCCTGACCAGTGAGCTAGAGTTCCACCT +TACTCCTGTGGAACTTCAAGGCCTGGGTCTCTTTCCAGGAAAATGTAAGCTCAGGGGGTG +GGTGCAGGGCAGGTGCTCTTCTAGCCACAGGGTTAACTCCCTTCACTCCCCACCCCCATG +CCCTCACTGAGTTTCTATCTGTCACAGAACCTCTGTCTCTCCCTGAACCACTGCCGTTCC +CCGTCCTAGCCCCCATTTCCCAGTGATGGCTATCCTTTCACTCCTGGAGTGGCAGTGCCT +TGCTCGTTCCCTGGGTGCGGATCTGGGCTTCTCAAATGAAGACAGCAGGCTGACCCTACC +TGTTTCTGATATTTAGCCCCCTGCTAGGCTACATCTACCACTCCTTGGGCCTGGCCCAGG +ATCTGGGCCAGAGGATGGCCCCAGTTTGAACCCAGAATCCATCCTGGGACTCTCTCTAGG +ACAGAGGTCGAAGAGAAAAAGTAGAGGCGAAGACTCCACGCTCTCCTCGCGGCGCGCAGC +CACCCACGCCCACCCCCGGCTTCCCTGCAACCTCAAACCAGCTCCCAGGGCCAGGAAGGT +CGTAGGACCCAGAGGAGCCCGCCTGACATTTCCGCTCCCCGAAAACACGCCCCCCAACCC +CTCCCCTCTGCCCCGTACTCCCCCACCCCGACAATCCCCCCCGCAACTTTCGAAGCTCTG +AGCCTCGGACGCCAGCCTCAGGACAGCGGCCAGCCTGCCTTCGGGCGGGACTCTCCTCCG +GACTGTGCCACGCCAGGACGGCCGAAGAAATGAAAGTGGAAGCCAGGCGGGCGGGGTGCG +CGGCGAGGCCGCAGGGGCACGGCGCACACTCACGGGTCCTCTTCTGGCCGTGGGGTCACA +TTCCCAGCCACAGGATCGCCTTTCTCCTGCAGGTCCCGCAGTGCCTGTTCTCTCTCCTGT +CAGCCTGTCCGTCTGCCTGTCCTGCCGGCCGCGGCTGCCCTCCTGCCCCGGGCGACGCCA +GCTCCG diff --git a/test/csq/ENST00000528237/ENST00000528237.fa.fai b/test/csq/ENST00000528237/ENST00000528237.fa.fai new file mode 100644 index 0000000..561f673 --- /dev/null +++ b/test/csq/ENST00000528237/ENST00000528237.fa.fai @@ -0,0 +1 @@ +1 59466 23 60 61 diff --git a/test/csq/ENST00000528237/ENST00000528237.gff b/test/csq/ENST00000528237/ENST00000528237.gff new file mode 100644 index 0000000..127468e --- /dev/null +++ b/test/csq/ENST00000528237/ENST00000528237.gff @@ -0,0 +1,17 @@ +1 ensembl_havana gene 21 59446 . - . ID=gene:ENSG00000079277;Name=MKNK1;biotype=protein_coding;description=MAP kinase interacting serine/threonine kinase 1 [Source:HGNC Symbol%3BAcc:7110];gene_id=ENSG00000079277;logic_name=ensembl_havana_gene;version=15 +1 ensembl_havana transcript 14712 28862 . - . ID=transcript:ENST00000528237;Parent=gene:ENSG00000079277;Name=MKNK1-022;biotype=protein_coding;havana_transcript=OTTHUMT00000387152;havana_version=1;transcript_id=ENST00000528237;version=1 +1 havana exon 14712 14770 . - . Parent=transcript:ENST00000528237;Name=ENSE00002192432;constitutive=0;ensembl_end_phase=-1;ensembl_phase=1;exon_id=ENSE00002192432;rank=7;version=1 +1 havana CDS 14712 14770 . - 2 ID=CDS:ENSP00000432665;Parent=transcript:ENST00000528237;protein_id=ENSP00000432665 +1 havana exon 17550 17623 . - . Parent=transcript:ENST00000528237;Name=ENSE00003471601;constitutive=0;ensembl_end_phase=1;ensembl_phase=2;exon_id=ENSE00003471601;rank=6;version=1 +1 havana CDS 17550 17623 . - 1 ID=CDS:ENSP00000432665;Parent=transcript:ENST00000528237;protein_id=ENSP00000432665 +1 havana exon 19178 19257 . - . Parent=transcript:ENST00000528237;Name=ENSE00003580253;constitutive=0;ensembl_end_phase=2;ensembl_phase=0;exon_id=ENSE00003580253;rank=5;version=1 +1 havana CDS 19178 19257 . - 0 ID=CDS:ENSP00000432665;Parent=transcript:ENST00000528237;protein_id=ENSP00000432665 +1 havana exon 23133 23230 . - . Parent=transcript:ENST00000528237;Name=ENSE00003517498;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00003517498;rank=4;version=1 +1 havana CDS 23133 23230 . - 2 ID=CDS:ENSP00000432665;Parent=transcript:ENST00000528237;protein_id=ENSP00000432665 +1 havana exon 25831 25932 . - . Parent=transcript:ENST00000528237;Name=ENSE00003482318;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00003482318;rank=3;version=1 +1 havana CDS 25831 25932 . - 2 ID=CDS:ENSP00000432665;Parent=transcript:ENST00000528237;protein_id=ENSP00000432665 +1 havana CDS 28477 28492 . - 0 ID=CDS:ENSP00000432665;Parent=transcript:ENST00000528237;protein_id=ENSP00000432665 +1 havana exon 28477 28577 . - . Parent=transcript:ENST00000528237;Name=ENSE00003620146;constitutive=0;ensembl_end_phase=1;ensembl_phase=-1;exon_id=ENSE00003620146;rank=2;version=1 +1 havana five_prime_UTR 28493 28577 . - . Parent=transcript:ENST00000528237 +1 havana exon 28837 28862 . - . Parent=transcript:ENST00000528237;Name=ENSE00002159407;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00002159407;rank=1;version=1 +1 havana five_prime_UTR 28837 28862 . - . Parent=transcript:ENST00000528237 diff --git a/test/csq/ENST00000528237/retained-stop-incomplete-cds.txt b/test/csq/ENST00000528237/retained-stop-incomplete-cds.txt new file mode 100644 index 0000000..8863bb8 --- /dev/null +++ b/test/csq/ENST00000528237/retained-stop-incomplete-cds.txt @@ -0,0 +1,3 @@ +14714 G A stop_retained|MKNK1|ENST00000528237|protein_coding|-|143R>143*|14714G>A +14714 G A stop_retained|MKNK1|ENST00000528237|protein_coding|-|143R>143*|14714G>A + diff --git a/test/csq/ENST00000528237/retained-stop-incomplete-cds.vcf b/test/csq/ENST00000528237/retained-stop-incomplete-cds.vcf new file mode 100644 index 0000000..6232457 --- /dev/null +++ b/test/csq/ENST00000528237/retained-stop-incomplete-cds.vcf @@ -0,0 +1,7 @@ +##fileformat=VCFv4.2 +##contig= +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO +1 14714 . G A . . EXP=stop_retained|MKNK1|ENST00000528237|protein_coding|-|143R>143*|14714G>A;type=ENST00000528237:47037783-G-A diff --git a/test/csq/ENST00000536784/ENST00000536784.fa b/test/csq/ENST00000536784/ENST00000536784.fa new file mode 100644 index 0000000..caae9a1 --- /dev/null +++ b/test/csq/ENST00000536784/ENST00000536784.fa @@ -0,0 +1,259 @@ +>11 11:60704556-60720002 +TCGTGAGGAAGGGCTCATGCCCCTTATTTATGGGAACCATTTCATTCTAACAGAATAAAC +CGAGAAGGAAACCAGAGCTGGGACTGCTGCCGTCTGTCCGGTAGAGTGAAGCAAGGGGGC +TGGAATAGGGCCTGTTCAGCCCCTGTCCCTGCTGAAACGGCTGTGGGAGGCTGGGCCCTG +GGACGCCCTCTCATAGCGTCCAGCGATCCAGACAAATAGGAGAGCCGTGACGGCCTGAAT +GCCAGCCAGCAGGAAGAAGTAGAGGTCCATCCGGCAATTGTTGATGTTCCCTGGGGAAAG +GAGGGGTTAGATTTGGGTCAGGACAGGGATCCTCTGTCTTGCGCCCTGTGCCTGCCGTGT +CCTAGCCCTGGGGCTGGCAACTGAGGCCATGTGGGCAGTGGTGGGATCTGAAGACACTGG +ACAGATACCCACTAATGTTTGACTTCCTGAAGATCTCCAGGGGTGTCTACAATTCCTCTT +CAGCTATTCAGAAGGGGGCGTGAAATATAAACACCATGAGAAAGGTAACCCTTCAGCCAG +AGATGGCAGAGTTCCAGAAGCAGAAAGGAGCCTTGGAGGTCCACTAAGTTCAACACTTGG +GGAAAGAAAGGCCCAAGGAGGGAGGCCACGCTGTGGGTGACTGGCCAAGCCCGGGCTAGA +ACCCCATTCTCCCAAGTCTAGCCCTCTACTTGCTTCTCCCCAGAGTCAAAGCACTTTAGC +AGTTGCCACCTCCTTTCCAAGCCTCCCTCCATCCATGTCCCACTCCTGGGGAGGCCCCAT +ACTCACCAAAGTCCTTGGGGCAGTGCAGCCAGCCCCCGGGCAAGGACAGCAGTGCCACTA +GGCTGGAGCCCAACAGTGAGCCCACCCCCGACAGGCAGAAGAAGATGCCCATGATGGCAC +CCTGCATGGAGCGCGGGGCCTCTGAGTAGGCAAACTCCAGGCCTGCAGAGGGGGAGCAGA +GACGATCTCAGGGGCTGGTGCAGGCGCAGAGAACAGGCCCAGGCCCCTGCTTGCTGCCCC +TGACCCTGCCCCCACCAAGCCACCCTCCAGGCTTCCCCTGGATGCCTGTCCACTCAGTGG +CAATGACAGCACCCATGCATCAATGCCGCCTTCCCCTCTGCCCTGCTCACCTGCCTCCTG +GCTGAACCCCTGCACCGGGGTACTCCATGCGCTGCCCCAATAGCTCTGTCTCCCCTCCTC +CCCTTCCTGCCAGGTCTATCATTTCAGTGACAGCACCATCTTTACCTCCTCTCTCTCCCC +ACCCTCTCTGCCCACCTTCAACGTCATCGTCAAATTGTTTTGATACAGCCTCTGAAATCT +ATTCTAAATATATGTCCTTCTCTCTATTCCCTCTGCCCTGGGTCCAACCCCAGCCCTGGT +CACTTTCTGCAAATGCCTCTTAAACTCCCCTGACTCCTGTCCTCCTCACACAGCCAGGAG +CATCAGTCTAAAGGACCTCGGATGGGGTCCTTTCCCGGCCAAAACCCCCTGGAGAGGAGG +GGCGCTGTTGCCTTCAGGAGAAATCCCAAGGTGCAGGCTCAGCGCACAAAGCCCTTCGAC +ACTTCGGCTCCCTGCACCTCCCATGCCTCTCCAGCCCTATCCCCCACGCTTCCCAAAGGC +TTGGGCCTTTGCTTATGCTGTTCCCTCTGCCTGTAAGACCGCTCCTCCTACCCACTCACC +TGCCCGCCTCCTCTCCATGCTTAAGGGCTCCCACTGCACTCTGCCCTGACTTCCACAGCA +CTCCACTGGCTCACTGTTTGCCTGACTCTCTCCCCATCTGAGTGAGCTCCCAGGGTCAGT +CTTTTCTTTATGTCTGACCCAGCCTAGCCCTGGGCCCGCAGCTGAGGAAGCCCTTGCTTT +TTTGCTGACTGAAGGGCCTGCCCCAGCCTTGCAGCTCTAGCTCCCAGCCCGGGGAAGGGG +GTTGGGAGGGTGGGGAGCGAAGGACATAGAAATCCATTACTATGACCCAGAGTACTGTGT +GCTATGATAGAGAGATGAACACGGGGCGGGAAGGGAGGACCCCTTCTGCCCAAGGACCTT +GGTATTTAGGCTCAGAATTGAAGGGGATATTGGAGTTCACCTTCAGTCTAAGGTAGAGGG +AACAGCAACTTCAAAGACACAGAGGGTGGAGAACCTGGCACCAGGGGAATACGTGGAGAG +CTGGTGTGGGAAGTTTCTTGCTCGCCTCCAAATCCCCAGTGCCTGTCACATAGGGGCTGA +CTTGAACCAGGTGCTAATTATAGACCCCCGTTGGGTGAATGAGCCCTGGTCAGAAAACAC +TGCCTTCCTCCATGCAGATGGGCCCTGGGGGCTGCATCCCTGGGGTACCTGACTTTGAGG +TGCCACCGGGCAGAGCCCATCACTGGTGCAGGAGCAGGGGAGGGGATCCAGGGTACCTGG +GATGCTGGCAAAGATCTCACTGATCCCAATGAGCAGGTACTGAGGGATCTGCCACCAGAT +GGACAGTGGTGCCGCGTTGTACAGGACCTCCCCAATCTGCTGGGACACGGTCTCGTTGTG +GTGGATGTAGTGTAAGCGCTCCATCTCCAGGACTCCTGGTGGAGGAGCAGAGGGGGATTA +TAGTCAGGCCCACCCCAGGCAGCTTAGCCCACAGAAGAGCTTGTACATGGTGGGGATGGG +GTACTCATGAAGCAGCCAAAGATTGAGCAGCAGGCAAGGAAAAGAATGCTGGACTGGGGG +GTGGAGGAGGGGGCCAAGATGTGACCAACTCCTCCCTTTTGGTCTTGGCTGCTAGAAGCT +CCAAGCTGAGTTTTGCACTCAATAACACTAACAACTCTCATTAATGGAGAACCTGTTATG +TGCTAGGCATTTACCATGCATCCTTGCTGCGGAAGAAAGTGAAATAACTAGCACTTTCAA +GTGCTTAACTAGAAAGTTAAGCAACTAGCCCACAGTCACACAGCTGATAAGTAGTCAGGG +CTGGATTTGAGCTCTGGTATGTCTGGTTTCAAAGCTGGCCTACTTTCCATGATATCACAT +GACTTCTCTACTGCAACGTCAAGTATTGCTGTAGTGTTTCTAACCTGGCTTTCAAGTTTA +ACTATGTTATCTCCTTCTCCTGTGTTGCTTGGGAGATAGCTGTGCTCTAGTGGAATGAAC +ATTGGACATGGAGTTGGGGGACCTGGGTTCCCAGCCTGGCTAGCTGTGTGACCTTGGGCA +AATCACTTAACCTCTCTAGACTCAGTTCCCTTACTCAAGAAGCAGGAATAACATTCCCAG +GATTATTGTGAGGATAAAATAGGACAAACTGCTTTAAGGATATAGCTGGAATAAAATCTA +GTTGGGTTTTCACACTTTCAACACAATACCGTTTATGGAGCTTTCATTTCTCCAGCTCAT +ACTTGTGATCCAGGCACACTACTGAGTGCTTTACAGACTTCATCTGCTGTAATCCTCACA +ACACCCCCCATCAGACTGAGTTCCACAAGGGCAGAGCCCTGCTCAGGGTCCGAATGACAC +CTGTCCCCATTTTAAAGACATAGCTCAGAGACTCTAAGGAACTTCAGGGTCATAAAGTTA +CTAAGTAAAAAGGGTTCAGGTTTGTGCAACAGTGTGAAAGACTTCTTTAGCTGATCCCCC +CCACTGCCCCCACCAACCCCCACTTTGTAACAAATGGCTTCAGATCCTTTTGAAATGGAA +GAAGGAAGATAATTTTTTTTTAAGTCTTCATTTGCCACTAAGTGGAAAATTCATTCAACA +CATTTATGGAGGGCCCACGTGCATGTTCATAGCAGTGAATAAAAAAAGAAAAACTATCTC +TGCCTTCAAGGAGCTGATAATTCACTGGGGGAAAATATTTGTTCCTCTCTCGGCCTGAGT +TTCTTCTTCTGTCAAAATGAGGGGCAGCTGGATTAGATAGGAGGGTCTCTTTCAGCTTGC +ACCTCTGGGAAGCCAACACTGACGCCCACTGGGAGAGGCTGAACTTGGTCCAGGCTACCA +CTTCAGCATCAGCCCATGGTGGAAGCAGACTTCCCCAAGCCCAAAGTTCAGCCCCCTGCC +CCACACCCCTCTGCACACCTGCCACAATGACGGAGGTAAAACCAAAGAACATCCCCAGCG +CCATCTTCTGCAGAGCAGAGGGAAGCAGCTTGCACCGCAGCAGTAAAGGGTCGATCAAGC +GGTCCTTCAGAGGGACCAGAATCAGCACCACCACAACATTGGCCAGGAGGAGCCAGGCTT +CCGGGATCTGGGCAGGAGGAAGTCAGGAGAGGCAGGCTAGCAGAGTGCAAGGAGCCTGGC +TGCAGTCAGGAGACCTGGACTCTAGACTGGCCCTGGGTGACCCTGGGGTCCAGCTCCTTT +CCCTCTCTGGAGTTCATGCTCCTCAGCTGTGTAACCAGGGAGTGGGATTATGTAGAGATG +GCAAATAGGTTCCTCTTGTATTCTAACTTTTATCAATTGGTAGTGGCTGATTATGGAACA +TTTATGGGCTCAGCATAAAAAAAGTCATGATTGACTAGTGATGTCTGCCATGGGCAAGGA +AATGGACTACAATGGCAAATTTCTCATATATCTGCCAGCTCTGCAGATCATTCATTTCAT +GAGTCTGAAATGCCAAGGAACTGGTTTAGAAAGTTCTGGGAAAGGCAGAGATCTAGGTAT +CTAAGGGTCCCAGAGAAAGAGGGGACAAGGAAGAGTTGAAAAGGGACCTAAGTATGCTTG +ATCTGAGGGTGCAAATTAGGCAGCGAGACCTGCTTCAGAGCAGCAGCATGGGGGTGTGCA +GCTGGCCTGAATTCCTTCAAGCAGTTGAGCATCTTGGCAGGATCCCTGCGCTGTGACACA +AGTCCTCCCACCCTCCAGGTGCTTTTCCTGTATCCTGAGGTTGCCTTGCAGGCAGGAAAG +GGGAGTGTGAAGGCAGTTTCATTTCCTCCTCTTCTCAGAGGAAGCCGCTACCTGGCTGAA +CTGGGTGCCGAACACATGCTTTATCTCTCACCGTGTAGCTGCTGCCCTGGGCTCTCAGGG +CCACAGAGATGTTGGCCGGGTTGGCTGGGAAAATGTTTGGGATGTGGAGGTGAAGACCCT +GCAGGACATAGGTGGACTGCATCTGCCAAGAGAGACAGGGGTGAGGCTGGAACAGAAACG +GCCATGCCCCCTCCCAACTCCTAGGTGGCATTCCTCAGCGCCGTACCACAGGACAGCTGG +GCAGCTGTCCCCTCTCCCAGTCTCAGGGAGATAGTCACCTTCCCACCCTCCTTTCTCCTA +GGTAGCTGGGCTGGGCAGGGAGCTTCCTGTGCTCTGCTCTCAGGCCTGTAGGCAGTGCGT +GCAGCCTTATCCCAGAGCCCAGGCACAGCTGGTCTGACTAGTATTTGTGTCCCCAGGGCC +CAGCACAGGGTAAGCATGGATAAATGTTTGCTGAAATGGGAAAGATAATGGCTGCCCCCA +CAGGGAGTTCTCATCTGACACTGAAGCCAAGCTGAGTCCACAGGTTGACACAAGCACTGC +ATAGACATGGACTTGCCAGAATGGCTCTGGACACAGCTGCAGGAGCAGGGCCCAGGGGCC +ACCTCCAATACCACGCACTGCCCCTTTAGTTGCTATATAATGGAGTAGGATCCAGGAGAC +TCCCACAGGAAGGGCTGGGGCAGGGGAGAGCATGTGGACTGCTCAGGGCAGCAGCCATTT +ACCAACTGGTATGGAAGGAAGTCAGTATCTGATTGGTATGACTGAGAATCAGCCATGGAC +ACCCTCCCACCACATGCCGCCATCTCATCATAGAAATACTGTGTGCCCCTAAGTAGCAGG +CTGGGAGCTCCAACAAATGTTCCTGTGAAGGGGGTATGGAAGGCAATGACCTTATGGCCT +GGGGGCTAGCATTAAGCTGCTGCCCACCCTCCTATCACACACACACACACACACACACAC +ACACACACACACACACACACACACAAACACATCACTAACCTCCCCACTGAGGAGTAATAT +GGTGAGTGGAAGACAATAGTTCTCAACTCTGAGTATCTGTATCATCTGAAAAGTTTCTTA +AACTAGAAACTTCCCCAGCAATTCTGATTCAATAGCCTGTGGTTGGACTTGGAATCTGTT +TTTAAAACAGCATATTTTTAAAAGCTCTGCCGGTGATTCTGAAGCACAGCCAGGCTGGGG +AACCACTGTTGCAAAGTACTCACTTTTGTGAGCTTGCCCCTGACCTGCCTGCCGTGGGGC +CTTGGGCAACTGACACACCCTCTCTAGGCCTCAGCTACCAAGTCGGACAATCTGAATGCA +GCAGAGCTGGAAAAGCCTCTCGTTTAAGCCACCCATTGTACACATGAGGAAACAGGCCCA +GAGAGATGAGGTGACTTATTCAAGGACCTAGCCTGGCACAAAGCCATCCCAGTAATTCAA +CTCCCGCAGGAGGTATAGCAGGAGGAAGCTGTCTCCAGAGTTCCTCTTGCCGTACCACCG +AGGGAGTTGGATTGCTGAGACGGCTTTGTGCCAGGCCCCATGCTAGCTGGTACGGGGCAG +CACCTCACTTTATTCCCAGACTTTCCCCCTTTCCACATGCCCTGGGCCTCTGTGATGAGA +AATGAGGCCATTCAGATGGTGAGTGGGGAGCCAGGCCCCCAGAGAAAAAGGGCAGGTATG +CTCACCTGGAAGTAGACCATCCAGTAGGGCACCAGGGTCACCATGACGGGCAAGATCTTC +ACCAGCACCTGGAAGTTGGCGATGTCCTCTTGCGGGGAAGCCCCTGGCTGGGGAGACCTC +TCGTCGGCCAGCACGCGGGCACATTGACGGTCTCTGTGAGACCCCAGAGGCAGCAGATAA +AACAACAGTCAAGGCTGGGCTTGGTGGCTTATGCCTGTAATCCCAGCACTTTGGGAGGCT +GAGGCGGGTGGATCACCTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAAGATGATGAAAC +TCCGTCCCTACTAAAAATACAAAAATTAGCCAGGCTGTTTTGGCGTGCACCTGTAGTCCC +AGTTATTTGGGAGGCTGAGACAGGAGAATTGCTTGAACCTGGGAGACGGATGTTGCAGTG +AGCCAAGACTGTGCCACTGCACTTCAGCCTGGGCAACAGAGCCAGACTCCCTCTCAAAAA +ACAAGCAAACAAACAAACGCAGCAGCCATAATCTTCCCCACCACCTCAGCCAACGTTTTC +ACTTCTACCATCACCCCCTAATTTAATCCTCCTCCCAGTATCAGCACGTCTCTGAAATCA +GTACCCTCATCTCCTCCACCCCGCTGTTAGCACCACCTTCGCCATCATCACCACCATCGC +CAAGGCCAGCATCCTTACTATCATCACCTTTAGTAAGGTGACTGCTGTCAGCAAAATCGT +CCTCTCCACGGGGTTTCCATTCACATCACCATCACTCTTTTTCAATGTTGGCACCACTAC +TGCCAATATTATTCTATCCTCTCTTTTGCTGCAAAAGTGCCTAGCCAAGACTCATTCCGC +TCTAGAGCTGTGGCCCCTCTGAGTCCTGAGGGAAGTAAGACCAGAGACTGTGGAAAACAG +TCTGAAGGGATTTTTTGGCTCGTAGCATCAATTTGCCACGGGAACCAGGGGAGTCCCAGT +CCAAGCCTGACTCAGAGAGAGACGCTGTCACAGATTTGATACACCAAAATTCCCCCCCCT +TGCTGTCTCAAGTCCATCCTCCTCAACAGTCAACATGGCAACCCTCTCCCTCCATGACAA +GGCATAGAGAGTGGAGAGGTGGGGGTAGAGGGAATATCAGTAGGCGACAAGATTGATCAA +TCACTGCTGCAGCCTTTACCCTTTGCCCTTTGCCCTTTGTCCTGAGAGCTTTCTGACCTC +TTTTTGTCCAAGAGCCTTGCACTGTCCTTTGAGATTCCAAAAGGGACAATATTAGTGTAG +TCATCTCCAAAGACAGCCACTGTCAACTCCACCCTTCCCAGCGTGTGCTGCCATTTTGCC +ACCAACAGGTGGAGTTTACTTTCACTGCCATTGTTTCCCTGCTGGCCTTGTGACAGCTTT +GACCTGTTAGAATGAAGCAGAAGTGGTGGTCTGGGACTTCAACGCCTCTTAAGGACCTTA +AGAAGACCCATAACTTCTGCTTTCTTCCTCCCCGGAACATTCATTCTTGGAAAGCTCCCT +CCTCTTGGAACCCTCACACGACGCTGTGAGAAGTTCAAGCCACATGGTAAGACCACACGA +ATGGGAACCAAGGTGCTCTGGTCCACACAGTCCCATCTGAGCTCACAGCCAACAGCCCAC +ATTGACTGCCAGCCATGTAAGTGAGCAGACTCAGAAGTTCTAGCCCTTTCCAGGTCCCAA +ATGACTGCAACCCCAGTGCCATCACGAGAAGCAGAACGGCCCGACTGAGCCCAGTCACTC +AGAACTGGGAGAGGAGATAAAAAGGTCATTTAAATCACTAAGCTCTGGTGTGGTTTGTTA +GGCAGCGATAGGTAATGAAAACCACCACACTTCTCGGCTCCTGACAACTTACAAACCTCT +AGCAATATGCCAGACTGGGGAAAGCATGTTCTTCACCTTTTTCATTTAGATCCTATTGAC +AGGAGCTGTAACTGGCTGCAAGGTCTGGAGACAGATTTGCTTGGCATAAGTAGACAGTTA +ATTTAGGAAGGCGAGGGGCAAAAGGAAGCCATGGGACCTATGCAAGGTCATTCAGAACCT +TCCTCCTTTGGATGTCAGCTAATGAGGAGGGAGCGAGTTTGGCCGATTTCCTAAGACGCT +GTGATGGTTAGTAACAGGGTAATGTGGAATTATTTACATTGTATCCTAACAGCCTTCATT +GGAAACATCATCCCCATCATCCTCTCCTTTAATGCCACTGTCATCCGCATTGCCAATGTT +TGTGTCTTCAGTGTAGATACCAACACCATCATCCTTATCCTTACTACCATCTTCACTGTC +AAGACCCTGATCATCCTCACACTTCCTTTTTTTTCATTTTTCTTTTTTTATTTTTTTCCT +GTTCTGTCACCCAGGCTGGAGTGCAGTGGCACCATCATGGCTCACTCCAGCCTCAACCTC +CTGGACTCGATTGATCCTTCTATGTCAGCCTCCCAAGTAGCTGAGACCACAGGCACAGGC +CACCACACCCCACTAATTTTTGTATTTTTTTGTAGAGATGAGGTTTCACCATGTTGCCCA +GGCTGGTCTCGAACTCCCAGGCTCAAGCAAGCCACCAGCTTCAGCCTCCCAAAGTGCTGG +AATTAGAGGGATAGCCACCGCCCCCAGCCCCATCCTCACACATTCTGTACGTAGATGGCA +ACCAATAATACCACCACCACTACCACCACTACCTTGACCTCCATCCTCAGTCACAGCGGG +CAGCTCTGGCCCACTGGAGAGCAGATCATCATAAAAAGCTATCACTGTAGCTGAACCAGA +ATGTCTGCAACCTGGACCATGCCTCCCCGGGAGCGATCCAGCGCTTCTCCAGGCTTGGAG +GCTCCCTGCACCCAGAGCCCCTCCTTACCTGGCCGAGTGTCGTTGCCACAGCTGGGGGCA +GCAGTTTTGGAGAGCGAGCTTAAGCATAGAGGACACTTGGCTGCCCATCGGGGGCTTGGT +GATGAAGACGGGGGTGGCAAAGAGGAAGATGAAAAATGCCAGGCCCACACAGCCCACAGG +GATGCTGTAGCCCAGCAGGAAGCTGATGTTCTGCTGAATAAACGCCACCACCAGCAGCGA +CAGCACAGCACCCAGGTTGATGCTCCAGTAAAACCAGTTGAAGAAGCGGCGGGTGGCGTC +GCGGCCGAGATCCATCACCTGCCATTCAGGAAGGGGTGACAGTGAGGGCCAAAGGGGTCC +GGGGCACTCTCTGTACCCATACCCCTCCCTCCTACAGAGACACTTCTTGGGTCAGTGGGT +GGTGGGCGTTCCGACACTTTCCCAGTCTCTGATCACAAACAGATGCTCAGTAAATATTTG +CTGAGTGAATGAATGAATCCTTCTCTTGGGAGTCACTTGCTAAAGATCAGGACATTTGGC +CCAGCTGCTTTTGCATACCCATGACACACACTGCTTTTTTATTGTCGCAGAGGAACACAT +ACAACAGATGTCTCAGATGGACTTGTTCATTTCTGGTTGATTTATCCCTTTGTTTTTCAC +TGAGCAACCTACACTATTCATTATTTTTTTTTTTTTGAGACAGTCTTGCTCTGTTGCCCA +GGCTGGAGTGCAGTGGCACAATCTCGGCTCACTGCAAGCTCCACCTTCCGGGTTCATGCC +ATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGACTACAGGCACCTGCCACCACACCTGGC +TAATTTTTTGTATTTTTAGTAGAGACGGGGTTTCACCTTGTTAGCCAGGATGGTCTCGAT +CTCCTGACCTCGTGATCCGCTCGCCTCGGCCTCCCAAAGTTCTGGGATTACAGGCGTGAG +CCATCGCGCCCGGCCTATTCATTACTTTTATAATCAGAAAAAAGCCAATAAGATCTCAGT +TTTATTGCACATTATTAAAAATGTTGTATGCATGTTACCGAAAGAACAGAAGTCTGAGCG +AGAATTTCCTCTGCAGTTCGGAGAGGCAAGCAGAGAAGCCTACTGTGACCCATCCTTTCA +CCCCACTTTTGTCCCTCTGATATACAGCAGAGGTGGTCCCAGGCACAGCCCCAAGAGTGA +GTTCTGGCCTGGTGAAAAAAACGTTTTTTTTCAGGCCTCCCAGCAAGGGCAGATGGGCTG +AAAATCTTTACCCAGAATTTGGATCAATCAGCAACAGCCAGGCCCCAGGCCCCTTCTGGT +CTGTTGGCTCCAGTCAGCTGCACTAGCTGCTTCCAAATCTCCCAGGCCCAGGTCCCAGAT +TCTGACTCAGCAGGTCTGGGGCAGGACCTGGGCATCTGCATTTAAAAAAAAAGCAGTGAG +GACTAGGGGCCATTTCAATGGAGAGAATAAATACTTCTCTACATTGCTAAACCAGTCACC +CTTTCCATGCCCCTGCAAATCTCAGGATCCATTACTGCCTTTCAAGTAGAGATTTATATT +TCCACTAGCTAGGGCGATTTTGTCAAACTTTACTTTCTGTAGTTGCATTGGGGAAAAGAC +AAGTATTTATTTTTCCTTTTTCAAATGTAAAATTATAGTCCACACAGATGCACTTAAACC +CGCATTCCATTGGAGATTCTGCGGGGTCCTCCTGGAAGTGGGGAGGGAGGGGCATACCAG +CTCACTGATAATTCTCGCTCTAGACTTTCAAGCAGAAAATTGAATAGGTCCCATTAGAAG +CAGCCACTTCCATTTATTAATTGGAAGTAAATGAATGTGACTATTGTAACTCTAAGGGGG +AAGACCAGGCAGCCCATTCAGGATATAAATGAGTTCTTTTAGAATGAGCAGATGCTTTGT +CGAGAGTGATGGATGGCCCTTTCTGAAATCAGCAAGTATGTGAAACACGCAGCTCCTGGG +GTATAGCTGTTGCCAGATGGTGCCAGTCCCACCCACCCCCACATCCCCATCTGACTGCCC +CCCTGAATTCTGCAGCCGCTTCCTGCCTGTTGTGAAGTACCCACTCTTGTTAACCCATAT +GCTATCTACACTGCAGCCGGAGCCATTTTTGAAGAGCTCAAATCCAGTGATGTCCATTCC +TGCCTCAAATCATTTTGGTGTTTCTGCACTGTCCTAGGGATCAGGTCCCGACTTCATGAG +GCCTTGTGGCCTGCCTTTGCTCCACCCAAAGTTCGTGCCCAGCCAAGGGGAGAACGTACA +GGAGCTTCTGGCCCTGTTGATGCCACGGGAGGCTCTGCTCAGTGGCCTGGCCTCCAGAAG +ATCAGTTTTGCCACAGGGGGTACTAGATGGGTGAGGCTCTCTGGAGGTCAATAGGGTCAA +TGACACAGGTTAAGGGTACTGGGTTGGGGGTGCTAGTGGGATGTCAATGAAATAATAGGA +TTAAAGGAAGATGAGAGATTCCCATTGACAAATATTGGGGGTCTCTAGGTCAGAAAGAAT +GTCAACAAGAAGTAAGAAACGGTCAGGGCTGGCCGGTCGCAGTGGCTCACGCCTGTAATC +CCAGCACTTTGGGAGGCTGAGGCAGGTGGATCACCTGAGGTCAGGAGTCAAGACCAGCCT +GGCCAACATGGCGAAACCACATCTCTCCTAAAAAAATACAAAAACTAGCCAGCGTGGTAG +CGGGCACCTATAATCCCAGCTACTTGGGAGGCTGAGGCAGGGAGAATTGCTTGAGCCCGG +GAGGTGGAGGTTGCAGTGATCTGAGATCGCACCTCTGCACTCCAGCGTAGGCAACAGAGC +GAGACTCCGTCAAAAGAAAGGAAGAAAGAAAGGAAAGAAGGAAAGAAAGAGAAAGAAAGA +GAGAGAGAGAAAGAGAAAGAAAGGAAGAAAGAAAGAAAGAAGGAAAGAAAGAAAGAAAGA +AAGAAAGAGAAAGAAAGAGAGAGAGAGAAAGAGAAAGAAAGGAAGAAAGAAAGAAAGAAG +GAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAA +GAAAGAAAAGAGATGGCCAGGGCTGGCCTGGGGGCATGAAGTCATCATCAAAGGATCCTA +AACAAGCTGGACAAGTGACTCCTTGTCAAGGACACTGGAAACTGCTAGGTGCTGAATTGT +GGGTGCCAATTGGATGAAACGATCCTTTTGAAAAATGTCCCCTTTATGAGTATAATATGT +GCAATCAAAGAACATTTGATAAACTGAGACAAGAAGAAAGTGCAATTAGTCCAGTGGCCT +GATCATACCACTGTGACAATCTTTTTCCAGTTTCCTTTCGTTGACACCTCGTCTTTCCAC +ATGGCTGCAGTCCTATCTGTATGCAGTCCTGCCTCCTGCTTTTGCTCATTTACACCATAT +GTGGTTATTTTAATAATATTACATTTTAGTCTAAATTATTGTCTAATATCCCACTGGGAA +CAGCTATCAAAATATAGCCGTGTTGTTGGGCATTTACTCATTCATTTAGCAAATACTTAT +TAAATTTCTTCTACGTGCCATGCTCTGTTCAAGGGGGAACGGAGAAAGGCTCAGAGGTTG +AGCTAAGGGAGAAGACCAGGCAGCCCATTCAGGATATAAATGAGTTCTTGCCCATGTGGC +TCCAGCTAGTGAAAGGCAGAGCTGGGATCTGAGCAAGTCGGCCTGACAGCCTCTAGCACT +GCTGGTAGGAAGAAGCTGGCTTGCTCCTGCCCTGCCCGCACATCCCCATAACACACAGAG +AGGAGGTTCATGGTGGGACCTGGAGTCCAGCTGCCTTTACTCGGCTCCTCGACCCTCCAT +GTCACCTTGGGCAAGTTGATTAATGCCATGAAACCTCTCAGTGTCTTTCTCTGTAAAATG +GGCATAATAATTCCTACTTCCTGGGTGGTGAAGAGTATTAAATCAGTTAAACAGTGAAAG +TGCTTAGCATAGGGCCTGCAAGTAGCTCAAAAAAGACCAACCTGCCTGGCGTGGTGGCTC +ATGCCTGTAATCCCAGCACTTTGGGAGGCCTAGGCAGGTGGATCACCTGAGGTCAGGAGT +TCAAGACCAACATGGTGAAACCCCACCTCTACTTAAAAAAAAAAAAAAATTACAAAAATT +AGTTGGGCGTGGTGGCAGGCCCCTGTAATCCCAGCTACTCTGGAGGCTAAGGAGGGATAA +TCGCTTGAACCCGGGAGGCTGAGGTTGCAGTGCGCTGAGATCGCGCCATTGCACTGCAGC +CTGGGCGACAGAGTGAAACTCCGTCTCAAAAAATAAAACAAACAAAAAAACAACCATGGT +TATTCCCACTGCGGTTGCCATCGGTTTTGCAAGGGCTAGCCCCCCTCTTCTTTCAAATCA +GGAAACTAGTGCAGGCAGGGGACCTGGTTTGTCCCAGGTCACGCTGGGGGCCAGCCCTCC +TTCCCTCCACACCCGCCGGAGTATGCCGGGGCAGGCCTCCTGCCACTCACCTGGTCGGCA +CCGAAGGAGGTGAGGTTGCTCCGGACGGAGCTGGCGGCCAGGCCGAGTAGCAGCAGGCCC +GCGTAGAGGACGGGCGCGCAGTAGGGGCTGGGCGAGGAGCGCGGGCAGCCGGCCGAGGGG +CAGGCAGGTCCCAGCGGCGACGCGGGCATCTCTCCGCAGAAGGAGCTGCGGCCGTCGGGG +AAGGCGGTGGCGGGCAGCAGGCCCGAGGCGGCCAGGTAGAGCAGCAGGCTGAGCGCGACC +GCGCGGTAGCGGCCCAGGTACACGTCGGCCAGCCAGCCGCCCACGGGCGCCAGCAGGTAG +GAGGCGCCCAGGAATACCAGCGCGGCGCGCGTCGCCTGCTCGCCGGTCCAGTTGAAGTTG +GTGCTGTTGAGGTACAGCACGAGGTTGGCGGTGACGCCGAAGAAGGCGGCGCGCTCCAGC +ATCTCCACCAGCAGCACGGCCGCGCCCGCCGCCCGCCGCCACCGTCGAGGGCCCCGCGCA +CCGCGAGGCAGCAGCGGCTGGCGCTCCCCGGGCACGCGGGGCTGCTCCCGGGCGCGCGGC +GCGGGCATCCTGGCTCCGGGCTGGGCCCCCCGCGGCTCTTCTCTCCTCTCCTCTCCCCGC +CTCAGAGCCCTGCACTCCTGCCCCCGGGCCTCGGCCCTCTCCCCCACCCAACTGGCTGGC +CCTCCTTTCTCACCGCTTTGGCCCACCCTTCCCTCCTGTCCCCTCTCCCTTTCTTGCCCT +ACCCTTCCTGTCCCTCCGCTCACTACCCGGACTCTACCACCTCCTCCCTAATTCTCAACT +CCCCTCTCCCTTCCCCCACCCCTAAGGCTTCCTCCCCGCGCCTCTCCTGCAGCTGTTTCT +CCCTAACTCTCCCCTCTCCTCCCTCCACCTTGACCCTTCCTCGCACTCTTGTTCACACTG +CGACCCTCCCTGCTTCACTTCGCTGCCCCTCCGCCTCCCTTTCCCCTCCCCGTTTGTCGC +CCCTTCCTGTTGTCCCCTCTCCTTATGACTCCTGGCCTGCCCTGGGCGTGGGGTGGGGGC +TCCCTCTGCCCCAGTCACCCTGCTGCCCCTTGCCGTCTTCTCCACCTCCTCCCTGTCCCC +CTCACCCCCACTGCCTACACTCCCCTCTCAGTCCCCTGCAGCCCTCCCCCCAGGCTCAGC +CTCTGTCCCTCTCTCGGCTTCTTGAGAAACTCTGGGCTCCCCTCGCTTCCCCTTTCACAG +GCCCTATCCGCAGTCCCCTGCCTGCATCACATGGCGCTACTGGGTGTTTAGGAGAAGTGA +AAGCCTGGGTCACAGGGCTCCTGCCCGGTCAGCTTTCTAAAAACCTCCCTCCTTCTCTAC +CTCTGCCTCCTACCCCAAACCCCCGCTGCTGGCCTCCTTAGAGCCAAAAAATTCCAGGAG +GAATTTTTTCTTTCAGTTTCATTTCTCGCCAGGATTCCACTTTTGCTTTACCCTCTTCCA +ATCAAACTCCACGCCTCCACCCGAGGCGCCACGGGTAGAAAGAAGTGGAAAGGCTACCTG +CATCATTTGGTCACACTCAGCCATTTC diff --git a/test/csq/ENST00000536784/ENST00000536784.fa.fai b/test/csq/ENST00000536784/ENST00000536784.fa.fai new file mode 100644 index 0000000..8e3a73f --- /dev/null +++ b/test/csq/ENST00000536784/ENST00000536784.fa.fai @@ -0,0 +1 @@ +11 15447 25 60 61 diff --git a/test/csq/ENST00000536784/ENST00000536784.gff b/test/csq/ENST00000536784/ENST00000536784.gff new file mode 100644 index 0000000..de4d625 --- /dev/null +++ b/test/csq/ENST00000536784/ENST00000536784.gff @@ -0,0 +1,9 @@ +11 ensembl_havana gene 1 15447 . - . ID=gene:ENSG00000110446;Name=SLC15A3;biotype=protein_coding;description=solute carrier family 15 (oligopeptide transporter)%2C member 3 [Source:HGNC Symbol%3BAcc:18068];gene_id=ENSG00000110446;logic_name=ensembl_havana_gene;version=5 +11 ensembl_havana transcript 1 901 . - . ID=transcript:ENST00000536784;Parent=gene:ENSG00000110446;Name=SLC15A3-007;biotype=protein_coding;havana_transcript=OTTHUMT00000396444;havana_version=1;transcript_id=ENST00000536784;version=1 +11 havana exon 1 290 . - . Parent=transcript:ENST00000536784;Name=ENSE00003535089;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003535089;rank=3;version=1 +11 havana three_prime_UTR 1 290 . - . Parent=transcript:ENST00000536784 +11 havana three_prime_UTR 433 466 . - . Parent=transcript:ENST00000536784 +11 havana exon 433 483 . - . Parent=transcript:ENST00000536784;Name=ENSE00002225178;constitutive=0;ensembl_end_phase=-1;ensembl_phase=1;exon_id=ENSE00002225178;rank=2;version=1 +11 havana CDS 467 483 . - 2 ID=CDS:ENSP00000441694;Parent=transcript:ENST00000536784;protein_id=ENSP00000441694 +11 havana exon 787 901 . - . Parent=transcript:ENST00000536784;Name=ENSE00002265924;constitutive=0;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00002265924;rank=1;version=1 +11 havana CDS 787 901 . - 0 ID=CDS:ENSP00000441694;Parent=transcript:ENST00000536784;protein_id=ENSP00000441694 diff --git a/test/csq/ENST00000536784/not-a-start-lost.txt b/test/csq/ENST00000536784/not-a-start-lost.txt new file mode 100644 index 0000000..cb1a0f4 --- /dev/null +++ b/test/csq/ENST00000536784/not-a-start-lost.txt @@ -0,0 +1,3 @@ +899 A G synonymous|SLC15A3|ENST00000536784|protein_coding|-|1G|899A>G +899 A G synonymous|SLC15A3|ENST00000536784|protein_coding|-|1G|899A>G + diff --git a/test/csq/ENST00000536784/not-a-start-lost.txt-l b/test/csq/ENST00000536784/not-a-start-lost.txt-l new file mode 100644 index 0000000..cb1a0f4 --- /dev/null +++ b/test/csq/ENST00000536784/not-a-start-lost.txt-l @@ -0,0 +1,3 @@ +899 A G synonymous|SLC15A3|ENST00000536784|protein_coding|-|1G|899A>G +899 A G synonymous|SLC15A3|ENST00000536784|protein_coding|-|1G|899A>G + diff --git a/test/csq/ENST00000536784/not-a-start-lost.vcf b/test/csq/ENST00000536784/not-a-start-lost.vcf new file mode 100644 index 0000000..9a1bbdc --- /dev/null +++ b/test/csq/ENST00000536784/not-a-start-lost.vcf @@ -0,0 +1,6 @@ +##fileformat=VCFv4.2 +##contig= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO +11 899 . A G . . EXP=synonymous|SLC15A3|ENST00000536784|protein_coding|-|1G|899A>G;type=ENST00000536784:60705454-A-G:incomplete 5'cds diff --git a/test/csq/ENST00000542803/ENST00000542803.fa b/test/csq/ENST00000542803/ENST00000542803.fa new file mode 100644 index 0000000..90eac5e --- /dev/null +++ b/test/csq/ENST00000542803/ENST00000542803.fa @@ -0,0 +1,5726 @@ +>1 1:107682629-108026080 +GAGGTACACGAGGAGTTACTGGAAACGGCGCTTCTGTGGAGGAGCCGGGGGGGATGGGGA +GTAGAGGGAGGGGGCCCTGTTGCCTCAGCGCCCCGAGGTCGTGGAGCGGCAGCAGCTGCA +GCCGGAGCAGCACCAGCAACAGCAACAGCGAGCGGGACGGAGTTAGGACCGCTCGGAGCG +CACAGGTCTCGAGGTAGTATAAGGTTTGCTATCCTTCCACTTGCTGGCAGTTGCAGAAGA +AGATCTGCTTTTTAAGTGAAACGTACATGCCACCCCTCCGAGGGCTGCGGCTTCCCCGGG +CTTGCTTCTTTGCCGCTCCTCTTTCCGGCTCTCGCGCTCACTCTTTAATTGGCACTGGCC +CCTAAGTTTGCCAGGAGCTCGCTGCCCGCTCGGAGCAGGGTCCCGGCCGGGAGCCGCTGG +TGGGGGCGGGGAGTCCGGGAGCCGCAATCCAGAAGCGTCGTGGGCCATGTATATTTCATC +AAACGGACTTTGGGTGCGTCGCGTCTCACTGCCATCAGTGCTATGTGCAGTGACATTTCT +GACTTGAGTGGAGGAATGCGCGAAGGAAACCCGGGCGAAATTGGTATTAGAGGATCTTCT +TGGCGCCAATGCTAATTGTCCTGATTTATGCCCCTTCTGACTAAGCTCAACGTCTTCATC +TGAAATAAAATGAAAGCGGTGCCAAGCGGCATAGAACCGCCTGGCCGCTGGTTCTGATCC +CCGGGAACCAGAAAATCGTCCTGCGGCTTGAAAAAAAAAAAAAGAGGAAAAAAAAAAGAA +ATAGAAATAGAAAAAAGAAAAAATATCCCTCAGTAAAAGTTTAAGGCGAGAAGTGTCAGA +GGCAGCGGAGCGAGGAGGCGCGGAGGAGAGCCGGCGAGCAGGGGACTGGGCTGGCACGAC +CTCCGAAGGCTGAGATCTCATTATTAATATCACTATATTTTTGGAGGGAGAGGCACCTTT +CTCATCCTCTCTTCCTCTCCGCCCACCCTTACTCCCTCCCCCTCATCTACCTGTCAAAGT +CACTGATCTTTTGCATTTCGGAAGAGGACGTCAACGGGAAGGAATTCCCCCTCTGGGTGC +GGGCTCCGAGAGGGGGCGACTTGCAGGAGGCTCCCCCCGGGGGCGGAGGCGAAGGTAATT +AAGCGGCGGGGAGTGGCGGGCCGGCGCTGGGTTCTCGGTCCTCGGGGTCCTCTCCCGCCG +GCGGCCGGGCGCGATCGGAATCCCCGGGCTGCGGCGGTGGCGGCGGCTCGGGTCCTCACG +CCCACCCCTCCCGCTCCGCCCGCTCCCGCCTGGGGAGGAGGCTCCGCGGGAGCTGCCGCC +CTCCGCCCGTACGCCGCCCGCGGGCTCCGCTGCTGCGGCCGCCGCCCGAGGCGGACCAGG +CTGGCTGCGCAGGGCCGCCGCCCCGCGCCGTCGGCTCGGCTCCCGCCCGGCGCAAGGGCA +AACGAGCCACACGGTAAGTGCCTGCGGCTCGCCTCTCCTACTGCGACCCGAGCCTCTCGC +CCGTGCCCCTCTCCCCCGGGTTTCCCCACCCCCCGCCGCCCCCCGCCCCACCCGCTGCGA +TGCACAGGCGGGAGGGAAGGCTCCGGGTGGGCGAGGAACTTTGTAAAGCGCCCCGAGGAG +GCAGCGCGCGGAGCCCTACGCGCACACACAGCGGCACACGCTCACACCCACACACAAGTC +TTCCCGGGGGTGCGCCCCGGGCCGGTGATGCGTCCTCTTGTTGTGTCCGGAGCCCAGGCG +TGGGGTCTGAGCCTCCATCCGCCGACTGACAGGGGCCCCGCGCTCTCCCTCTCTCACGCA +CACCTGGCCACACACATCGCTCAGGCGGCTTGTCGTTATTTTTTCTTTCTTTCGCCAATT +ATATTTGTTTGGGGAAAAGCAAACAAAAAAAACAAAAAAACACTTGCCCTATTGCCGGCC +TTGGGGATCTGGTGGCCACATCGAGAGCTTTTGAAGTCCCTTCTTTTAATCGCCTTTATT +GGTGCTAGATTAAAACATTACTATCCCATGTTGTGCAGCTGGGGAGAAAGGGAAATTGAA +AGAGGAAGACTTGGTGTAGGGATGCTGTTTGGAATATTCTCTCATATTCTTTACTGGCAT +CATATTAATCGGTTGATGGATTCGGCTAGGGACACTGAATTGCACTCCTGTATGGATCTG +TGGATATCTATATATAATACAAATAATACTGAATATTATTGGGCCTAAAATAACCAATTA +AGTGATTCATACAAGGAAAAACTTAGATATAAAAAGAAACTGCGCCCTCTGCTGTTAATT +TTAGTACCCTCACCCGGGGACTTTTTTTTTTTTTCCTTCAGAAATCCACTTAAGAGTAGG +CTGTCATCTTACAGGGCAAGGGAAGAAAATTCCTAGCGGGGATTTTAAAGCAACTTTACT +TGGAAAAGTCGCAGGTTGAGCTCCTATAGTTGCATCAGGTACAGATTTCCAGTGAGTAGA +CGGTCCTCCTCTCTCACCCATTCTTCTCTTTATACAGGGAATAATGGAGCCACTCCTCAT +AACAAATTGTCAATCTTTGGAATGGAAAATTCTGAGTAAGATTCAGAACTCCACTAAACA +TATGGTGAATCTGGCAGTAGAATTGCTCTAGAAATAAGGCCCTGTTTTATGACTGAAAAT +ACTAAAAGTTGTTTTATCTTACAGAAATGAAAAAAAAAAAAACCCAGGAAGATCTTCCAT +TAAAATCACTTATTCAGATATGCTTAGTAGTTAAGCTTGTTGGAAAGTTTTCCAAAAAAT +AATTTTTTTTTTTTTCAGGGGAGGCTTTTCTGTTTTGTTTGTCCCTTGAGGAGGATCTCT +AGTGAGGGAATTAGCAATTCCACATTTCATTAAGTATTTTGAACTGTGTCACTTTGAATG +CCTTACCCGCCTCCCTTTCTCTTTGGCAAAGGAAAAGCAGCTCAGTAACTGTCCAAGATT +CTTTTTGAAGATAAGCAACTTTCGATTTTTCATTAAGATAAAATTTGGATCTCTGCATGT +GGATCAACATGCAAGGAAAAATGTGCATCAAGTATTTCACATGTAATGTTGTTCCAGGGA +TATATTTTCTTTTCTGGATGCCGTGAAATGAGATATATTTCACCCACTGAAGACCACCAT +GAAGGCATTCAGGATTCTATATACTGCACTACTAATTTGGTGGTATTTCCTTACTGTGGA +ATTTAAGACGGATAATCTTAAAACTTTTGCATGGAAACAGTTTATTTGAACATAAAGCTG +GTTTCCTGTTAATATTTTTGTTTTGTCAGTTTTCAATGGGTATATGTGTTAAAATGATTC +AGGTTAGCCTTTTTAGGAGGAGGCAAATGTATTTTGCAGTTTCCTTTTGTATATTTGCAA +GTGGTGCAAATACCTATTTTTGCTTCCATTATTATTCTGAAAAATATTCAGGTAATTTGT +TTAAAAAGTTAAACCATTACACATTTATTTGATAGGATTTCTAAGTGTCATAAAAATTTG +GAGAGTTTTAGTTACAAAGGCATCAAGTCACTTGGAAAAAAGAAAATTGGATTCAACTTT +GAAAACCAATTATATGTTAACATTGAAATATATGTGTGTGAATTATATTGTATAGGAGAT +TATATTAGTAAAGTCTTAGGTTAGTATGAGATTTAGCATACTTTAAAAAATAATTTTATT +TGCAGAATCCAAAGTTCTGTTTCAAAACTTCAGGTAGGTGTAGATTTTCTCATATATGCG +TTTGAGACCTTAGATCTCTGAACTTCCCTGCATGAGAATTAAATATTTGTTTTTCATGTG +GTAATTAAATTCCAGATTTCTTCTAGGCTTAACTGATTCTGAAATAGTTTTGGGTATTAT +CCCATCCTCAATCATCCTGCAAAACATGTGCTATCTAATTTCTTGAATCAGTCTTCTCTC +AATGAAAATAGAGATCTTTCAATTACCACGGTGTGTTATTTGGGTTTATTAAGAATCTCA +TGATAGACAGTTGCTCATAATACCCAATCAAGTGTGAGTAAGCTATGCCAATGATGTTGC +AGTACATATTAAATTCCTTATATTTTGAGAGACAGTTAACAAAAGGATAGAAGCATATGT +TTTCCATTAAGTTGACTAGAAAATGCTTTCTTCAGAACAAATAGCTGCAAAGAGCATTGA +ATACATGTTAAAATATCTTATGTAATAAATTTCATTATGACTGTTGGAAGCTGCTAATTT +TGATAGGTTATAATTTTGTATATCTTTATCTTTTTATATTTTCACTCAATGATCTATATA +GTCAATTTTCCTTTTGTTCCTTCCCATTCAGAAACATGCATATTTATAAAATTCTTAATG +TGAATGAGGAATGAGTCAATAGTTGTGTATTTCAGGTACCCCTGAAAAGCTGAATATTTA +TGAAAAAAATAGCTTACTACCACCATTCCCACCTGCTAGTGAGATTATATAATAAAATGA +ATGCTGAAAACCAGCTAGATTAGGAGATTTACTGATAATGTCTTCCTCTCAGTTGATGAA +ACTGGCAATTGCTTTTGGAATATAATTGCCTGTAATATTAACCATTATTACTTCCATGTA +ATATTTTGGGAGGCTTTTTTTTTCTGGTGAAAGAAAGGGCCTGTGAAAATGGCTTCTGCA +AAATTAATCCAAGGTGGAAGGGAATTAGCTGCAGAATCCTGGACAAATACATGTTTTGTG +TGTGCAAAGGCATTTTATAGCCCATTTTAGTCCTGATCAATAATCTCTATCAACTTGAGG +GCCATGACTTAATTTTACCTTTTATTATTGGTTCTGCAAATTTATACACCGGAGGTCTAT +GGGGTACTCACAACCTATTAATGGGTATTTTTATCAAAGGAGACTTCTCAGTACTTTAGT +TCCCAAGTAGAGGTGGTAGCATTTTTGATTACAGTGAGTTCCCAAGGTCTGCAAAGTGAA +GAGGTAGAACTGGAGCTGCCCAGAGCTCTTATGAATCTGTTCTTATTTAGGTGATACGGA +CACCTGAGACAAATTTAAAGGCCACGTCACTTCACAATTAGTTCAGTTATGGGCCAGAAG +GGATAGGTTTAGTATATTAAGTCCCCAAATATGTTATTCACTGTCCTTCTCATAATTGGT +TTCCCTAGCTATTTGCTGTGATGACCTAGCTTTTAAGAAGCTATTGATAATTTTAACCTG +TTTGAAAGCACAGCAGATAGACACAGTGCCATTAAATAGTGGAGGTTAAGTTGTAAATAA +TATTCTATTTTTACATCATTGTATTTTCTTTGAAAACTCTGTAATTATACTTTAATAACA +AATTCCTGATTTTCAGAGGCTGCTTTTCCATTGTGTGTCATGGAAGTTCATAGATTTAAT +TTCTTACTAATTTGAAGTTAAGAGGATTTCCTTTGAAGTATATGTGACACTGAAAAGTAA +GAAGACCCTGAAATGCAGGATACATAACAATAGTACAAATATAAAAATTAGAATGAAATC +AAATAATTATGTTAAATAACAGCTTAGTGTCCCTCTGCTCCTGATCTGTAATACGCCGTG +GTCAATATCTTTTTCTGTGTCAATGGGAGCTCATTAAATGTAAACTCTGCAGACTAACTG +AGCCATGCCATATTAGTGCTTGCCAAAGCTTGACATTTTTAATACATTAATAATATGTCT +GTAATGTAATGGAAAACTATTAATCACAACTGGTTATGTGCCAGAAATTTAAGCTATAAT +TGGCTGCCTCTTGTCAAGAATGTCTGTTGCACAGTCCTGCAACTGCCTAATATTCAAATA +TCTTGCACTCTTCTGCATTTTTCCTTGTCAGTTCTCTAAATTCGATCAATGGTGTAGTCC +ATAATTCTGTGTAATGACCATCATTATAATCCTGGTATACTTTAATGAGAATTCGTTATA +TTGGGATTGCTGTTGTGTCAGGAGATAGCAAAGGGTTCACATATATTTCCTTAGTGTTCA +AATTTTTCCTGTACAAATGTATGGTCACCCTTTATTTTGTGGTTGCAGTAATGCAAAATG +TGGTTGAGGACAGAGTAACCGAGAATAAATGGATGAGGAGAATATCATTTGTTGGTTAAA +AAAGAAAGTGAAGACTAATCTCAGGAAGCACTCAAATATATTTAAAGTGGTATTTTCAAA +CTAATATTAAAAATAAACACACAATGCTCACTCCATTCAAACTCAAAACAGTCAATTCCG +GGTCTTCAAGATTATATCATTCTTGATAAATAAATTACTGTGTATTTGAAACTAAGAATT +AAAGTTAATAATTTCTGACCTAATAGATTTTACACTGCTTCAGTTATAATGCCTCCATCC +CCCGGCCCTTTGGAAAGTATTTGTTTCCTCTTATAAAAACTAGTAAACACAGTTGAAAAA +TTCATCTCAAAAATGTAAATTTGTATCATTTTAACACCTCAGATTATTAATTGTCAAATT +GTTGGATGTGTCTGAAAATATCAACTTAAAATTACTAATGAATCTGAAAAAAAGCAGAAG +GCTATAGTAGCCACAACACATGCTTCTCTGATTTTTTTCTTTTTAGCTTAAGATTTCAAA +ATGGGCTTTACCCAGTATAGTTTTTAGGTTACAAGGAAGAGGCTGATTCAAATCTGTAGT +TTATACATATTTAGACAAACTACTAATTATTGCTTCATAGGAACTCAAATATTCAACACT +TTTTCTATTAGAAAATATCACAAATTGCAGCTGTATGATAACATTTTATGAATTGAATAT +AATGAAAATTGCACTTGCATCCATAAAGCAATTATTATAAATTACTTTGCTATGGAAACA +CAATTCAACCATCTGTTGGCATTTCATAGTCTCTGTGGCTTAGTTCATTTTAAGATGGTA +CATTATTTAAATATAATGAATTCCCTTTATAAGATTGTTTGAAGATAGTGAACTTCCATA +TTTCAACTGTTTAATGTGAATTGAAGGGTCTATAATAGAATTTTCTAAAATTGTAGGCTT +TTTTGTCCTTTTTGCATTGCTTAAAAATCAGTTAACTTTTAGACTATAAATATAAGCAAT +CTAATTAAGAAATTATACTTTTTAATACCTGGTTTCCAAATGTTAGCATTTGTTCAGATT +TGGATAGTGATCTCTAAACAGAAAAGTGGCCAGTTAAACTCACCAATGACTTGTAGCCAT +AGTTATGTAGGATGCATTATCAGTTAATCAAAAGTACTTTTACACAGTAATTTTTATTTT +CTCTTAGAATTAGTGCCATATTATTCTGCTTCATGGCCTGTTAACTCACCCTCGGCTATT +TTTATGTGTGCATTTTAAATTGTGCGTTTTACTACAGAGCTTTTAGTTTTAAAGCAGCTT +ATAATATTCGCCTTTGGGACAAATTCTCTTCTGTTACAAAAAGTAACGGCAAATGCAGAT +GTAATGGCTATAAAAAGATGTAAAAATATAGAAAATTCTTATGAAAGGAAATTTTGCTCC +TTTGGTTTTATTTTTGATTTTTTTTTTTCAGAGAGCCAACTTATCTTTATTACTAAATGC +AACTAAACAAAAGATGCTAAATTCTTCCAATGTAATGAGCAAATCCACAGGGACAGGCTT +ATGCCAACAATGCGGATTTTCACTCCAGCAAAGAAAAGCTAAGAAAAGTACAAGGAATTT +GGAGATTTTTAGGGTCTCTTTGCCAAGAGACAAAAGGGATATAAGTAGTTGTCATTTCTT +TGTCATCATTATAAAAGTGCTCATTTACCCCATTGTTCTCTTGGAAGATTTTCTAGCACT +GCAATGTATGAGAAATGTTCAAATCTAGCTGCTTGCTCTCAGTTTTGTCAAGATGGAAAT +ATAATTTTTGAAGTGAAAACCTGTAACTCACGCACACGTGTCTGTCTTTGTTATGGAAGA +GTTAAATCCTTCATATTAAAATTCTCCCCAATGTGAATGATTTCCATGGTTTGCTCATTC +TAGCAAAGCAGCTGAGTAAAGGTTATCTGTATTACACCAATTTGCTTTATATTGCATCAG +ACCTCCAAAATGTCAACATATTGTACATTTCGTAATATATTGATTCTGGGACAATAACAC +TTACTCTTATTGTTTCTAAAAGGGTGTTGGTGCCAGAAGAAAAGAATGATTGATGGGAAA +CAGACACCGGGCTATAGACACTCATCCTTTTGCTTCAGATACTGATATCTCAGCCTGCTT +GAGCATCCCTTGTGAGCTGTGAACATTGAGGATCACTCAGGGTTATCGGATGTACAACGG +GAGAGCCATCGCTTTGCTAAATTATTATCTGCAATTGGACATCTTTTACAAAAACCAAAC +TAGACCTGAGTCTAATAGATATGTTCTAAGACAAAGAAAAAGCTGCAAGTTGTTAACGCC +TAACACACAAGTATGTTAGGCTTCCACCAAAGTCCTCAATATACCTGAATACGCACAATA +TCTTAACTCTTCATATTTGGTTTTGGGATCTGCTTTGAGGTCCCATCTTCATTTAAAAAA +AAATACAGAGACCTACCTACCCGTACGCATACATACATATGTGTATATATATGTAAACTA +GACAAAGATCGCAGATCATAAAGCAAGCTCTGCTTTAGTTTCCAAGAAGATTACAAAGAA +TTTAGAGATGTATTTGTCAAGATTCCTGTCGATTCATGCCCTTTGGGTTACGGTGTCCTC +AGTGATGCAGCCCTACCCTTTGGTTTGGGGACATTATGATTTGTGTAAGACTCAGATTTA +CACGGAAGAAGGGAAAGTTTGGGATTACATGGCCTGCCAGCCGGAATCCACGGACATGAC +AAAATATCTGAAAGTGAAACTCGATCCTCCGGATATTACCTGTGGAGACCCTCCTGAGAC +GTTCTGTGCAATGGTGAGGTAACCCTTTTGCATAAAATATTTCATATAAATAGGGTCTAA +TCGCATATGCATACAGATGTGGTGAGTGTGAAGACAATTCATGCAATAAGTTGAATCTGC +AGGTGGCAGATTTGTGTTAACAGGCTAGTTTCTTTCTCAGTGGAGGCTTACACTGCCTGG +AGTTACAATTTGTGCAGGGTGATTGATGCCCTGGAAGGAACTTACTTTCCGCTTCCCTGA +AAACCTATAGTTTCACTGAGGCAGGTACACTATAGCATATATTATAAAAGAAAAAGTTCG +ATTGAAAGTTAAATTTTAGATTGGAGGTTGGAAATATGATTAGGTCATATCTGTCATGTT +AAGGATAAAATGCATTGGCAAACCAACTTTAAAAACACAAATGTTTCTTCACATATGTGT +ATAAAGCCAGTCCTAAATTCTGTAGTTCAAGGAGAGACTAGATCTCATAATTATGTTCAT +CAGGAAGCTGCTATGATTTGGGAGTCCTTGGTTAGGAGATCAGCAAGAAAAAAAGTAGAG +GAGAGAGGAACTAAAGCCTTGTGAGAAGTTTTTCCAGAAAAATCTTATTTGCCAACTCCC +CTTATTGTCAAGGTCATAGTTTTCTATGTATATTTTAAAGATGACTTTTGGAATATAGAA +AACTTATTTGCTGAAAAGCAAGGACTCAGCATATACAAATTCAGATACTTTTTTTTGATG +AGCAAAGTTACAGAATTCATTGTTCTGAAGGCTTATATAAGTCCTTTTTTTTCTGCATAG +AAAGTTAAATACCATGTGAAAAGGTAATATTGGAGTAACACATTGAATTTTTAAGAAAGA +CATGGCTGACAATATTTCTATAAGTATTAGTAAAGAGGCTGGTGATTAAAATAGTATACA +TTAATGTGCTAAAGAGTTCAGATGGTGAGTTCATTTGGTTTTTTTTTTAATTATAGGTGG +TTTTTATTTGATAGAAGAACTGCGATCCTGTTTTTCTCCACATAACAGATATAATTGTAT +GGCAGATTTTAATAATAATCTTACCTGACTATATTATCTTGAACCTGGCCTGGCATTTTC +AGGATAGTGAAACTATTAATCAAAGTAGCATCTGTTCACAGTCCCCAGTGAGTTAAATTA +GCATAAGATCATCTTAGACCTAGCACCATAAAAAAGGTTTTGTAACAGGAAACAATTTTG +AGCAATAAAGAGTGTTTTCACCTTAAAGCTAAGGGCTTGCCATTTTTCAGAAGTGCCTTT +GGGGACTGGTTTGAATTATAGTCTAAACCTGATTTTGTGGAGAGTGAGAAAAAGCACTTG +GCTATTAGGTGTCACTGTTACTAAAGTGCCCTGAAAGACTAAATATTTCAAAGAGAGGAC +CCGTCTCTATGGGAACAGGTATGTGCTTTGCAAAGAAGTTGCATTTTGGAAAGCAGAGAG +TTCCAGAGAAGGAGTTTATTCAAACACATTAGCAAAATCATAATAAATCAGTACAGGAGC +AGAGACATTTGTGGTGGCTTTATGTGAGGTCTTTAATAATTTCTCATGAAAGGTCAACTA +TAAGAGCTCATTACAAATCTGGGTTGAAATTGCTGTTTGGGTGATAGGTTGTATAGTCTT +CTACGCCTTATAGCAGAGGATGAGTTCCAGGCCAAGTCTGCATATTGTTAAGAACTCTCT +AGCTCTGTATATTGGTTTACATGACACTTGTAACAACATGTCCCTTCTGGAATTGTTTAA +TAATTTACAGATCTAAGTAAAATAGCAAATTTCCTTTCTCAGGGTGCTGTTTTCCCTCTC +ATAAGCCCTGTGTGATGTTTTCAAGGTGTGATTTGTGGGTGCAGCTTCCCTGATCTCAGT +CTCTGGCCAGAGAATGCTTGCTTAGCACTGCTCCTGTCTGTCATGTTGAAGGGTTTACTT +GGTGTCTTCAGCATGCCTCTTCCTCCCATCATGAGTGCAAAGGGCATGTTACGGATCTTC +CCATGCCTGCCTTTCAAAGGGACATGGTCTAAGGTATTTAAACAAGTCCATTCCTCTCAG +TCCATTGGCTAAGTGATGTTAGAGACCAAATGGGAAAAAAGAATTAAAATGATATCCCTC +AGCTTTCTCAAGTGCAGTAATGTGTATACTATGTATGTTCACATGAAACTCCGTAGGACA +GTCTTTAAAAGGCTGCATCTTAGTGTGATGCGGATATTTGGAAGCCCTGGTGGATGTAAA +CTTGTCATTGGACAGAATGGTTTTCCAAGGGAGAATGTAAGATTTGTGAAATATTACCTA +TCAATGCTTAATTTGTATTCCTTAATATGCATATGATAGGCATAACAAATTTAATAATCT +ATCCTTTAAATATATACCTTGTGACTATTTGTATGCATATTATATACCACGTCAATGGTA +ATGGCCTAATACAGCAACACATTCACTCTGCAGTTTTGGATGTTCCATAAAACTCTTTAG +CATAAGGATTCCTGACAGAAGGTTGGGAAACTGTCTCAGGATGCTGTCATATCAAACCTG +TTTAGGTACTCCTTAGCCCAGGGTGTAATGGGGATTCATAAAGTCATTTGTGTTATGACT +TATGCGTTCTCCCCTCCTTGACGCTTGCATCCATACCTGCTCCCTCAGAGTCATTATGGC +CTATTACATCAGGGGAGCTGCCACATGAGTACAGCCACTGCTTAGCCCCTATATGTAAAT +GTTTGCTGCAAAATTGTTTCAGTAATCACTTGTTCAGCTAGTGACACTCCTATTAGCTGT +GGCTATAGCTGTTCTGAGCATCGAGGGAACATGTGCTGAGAGAAATACCTATAATTCCCA +GGGCCAATTTCTTTAATATAAAGTTGAAGTTCATTGGCATTGCATTAAGAGTCCGTGTTG +CTGCTTTTTTCATTGACTTCATCATTATAGGCCAGTGACTATCCATGAATGTTGCATTTA +TTTTAATATAGAGTAAAATTTCAGGAAAAGAAGGAGCATATGGATTCCATTTAACAATAG +ATCTCTGCTTATTAACCTGGATGGCATACTTAATAAATCTTCAATGTGAAGTACTTTAAA +ATTGTTCTATATTAATTGTACCAGTATTTATAAACATTAGTTTTTCAGGAGCACACTGCC +ATTTCTATTAATCATAGTGGATAAGGAAGAGGAATATATATATATGCACACACATATATA +TATACACACACATACATATATATATACATACATATATACATACATATATACACATATATA +CATACATATATACATGTATATACACATACATATATATAAATTGCATATATTGAAAACCAT +ATATTTTCTTTTTAATTTGATATATTCCTTTTGAGTTGATGATGGCTAAAGAAAATCTCT +GTTTTTGTCAATGGGGAAGAATCTGAAGGGAAGGTGGGGGTTAACCCTTTTTTTAGGCTG +GGAAAACACATTTGAATAGATCCTATCTTTTCAGCCACATTGAAAGCTTCAGGTGGCAGA +GCTTTGTCAGGAAACACAGATCATCTAGTGACTACAATTTGTTTCAATTTGCATAAAGAG +CAGAGAGGATGATCTGAACCTGTGTGTAAAGCTGAAGTGACAACACAAAGCTATGACTTT +TTCTTTGTGTTTAGACAAACTTAGCTGTCATATCTTCCCGCACACCCCAGTGGCTTAAAA +ATGGCAAAATTATCTGCAGTTATCTCTAGCCTGCAGCTAATTTTCTGGATAAGTTAAACA +GACGCTTTGAAAAGGAGCCTACAGACGGAAGAACTCATGTGTGTTTATACAATTTATGGC +TCAGAAGTGCTGATCACTGTAGAAATGGAAGCCCTTGAGTGCTGCTATGGATTTCAGAGC +CAATCAAAACTAAATTAGGAAACAAAGATTATTAAAAAGTCTTCTGTGCATGTAATTTTG +GCATAATATTATGAGGTGGACATTAAATGTTTCCCTTGGAGACGTTCAGCATCATTAATG +CAGCATGCCTTTAATTACAAGTAGACTCATATTACTAAAAAATTGGAGAAAATAAAGTAC +TCTGAGGTACAGTTAGCAATAACCTCATTATGTTTACTGAAATAATTAAAAGAAAAGGTA +TAATTTTTCTAAATAAAATGTCAGAATGTGAAATGAAAATGGATTTTACTTAGGAAATTT +ACTAATGTGTGCCTGTGCTCTCGATAGGCATTTATTCAAGTACCTTAACAGATCTATTAA +TGATCACTCCATATTGTGCTATTTCTAGATAGACTTCTATTATGAAAGAAACTTTAATTA +TTGTAAGCATTGTGGATAGAGCATATTTCATTATGTTCAAATGGAATTTACGGAAGTGGT +ACAAAGCCTTTGTGTTTTGTGGTTTCAAAGGAACGCTGAGAGATGAGTGACTGGTAACTC +ATAATCTCAGGGCTATCTATAATTTCAAGTTCTGATTTACCTTTGGCTCAGGTTGCCATC +TGGTGGCTGTCAGGTGACCCTTGAGAAAAGAACTTGATAAATTCAGTTACATTTTCCATG +ACATGGAATTACTATCAATTTTCCAAAAACTGGAAATGACATTGATTTATATAATAATCA +AATAATCTTAAAAATACACTCTGTTCACATGAAACATAATTCAGTAAATGAATGAAGTTT +TAGTAACAGTGACACCTTTCATTTGAACTGATTTATCCCTTAATTATGCCAAAATGGAAT +TTTTAAAAACCTTCAGTTCTTTCATTATTAACACTTCATTGTTATTAGTTCATTATTTAG +ACTTATTTCTTAGAAAAGTTTAACTCATGTTTGGAATGAATTAAGTTCCAAGGAAGTCTT +TCTCATATACCACTATATCAAGTATTTCCTTTTTGAGGAGCCTACAATAGCTCCTTACTA +TCTATTGCATCATGTCTAAATTACTCTACCTGTTTTTTGAATTTGGGTGCATACAGCCTA +TCGTCCACTACTTCTCATCAGGACTCTATAGCATCTCCAGGGGACTATGGCTGGCAATCT +GATTGGAAGGGGACAACTGGATTTGAGTTGAAACTGCCTTGGCATAGCATGCATGGCTTG +TTGGAGAGGTCTTAGGAAGGAGCTGATGAAGATTATGGCAAATGTAACAAAACCTAAAAC +CACCTCATGTCATTTATTGTCCCAGATAGTGTGCGTAAGTGCTCTTTGTTGAGCTAATGC +CTCACAAACATTACTGCAAACCATTGTTTGCAGAGTGAAGTGAACAGAGCATTCAGCACA +TGCAAAACCTAGTGGTGGTGGAGATAACTAATGTCGAATAATATATGGTCATTGCGGCCA +ACAGAAGTAGAGTCCTGAGCAAACTTAATACAAAGTAGTGTGTATACAGAGGGTAGAAGA +ATAGAGAAATAAGACCAGCACTCAGAATTTAAAGGTGAAATATTATTTTGCAACATGTCA +AAGGCCACTTGGAAAATACTATCTGGTAGCCAAATGCCAGAAAAGGAGAGAAAATATTAA +ACAGTGCCAGAAAGGGAGAGAAAATAAGGCTGGGTTGGCCAAGTACAGTGGCTGATACCT +GTAATCCCAGCACTTTGAGAGGCTGAAATGGGTGGATCTCTTGAGCCTAGGAGTTCAAGA +CCAGCCTGGGCAACAGAAAGAAACCCCATCTCTATAAAAATTAGCCAGACAAGGTGACAT +GCGCCTGTAGTCCCAGCTACTTGGGAGGCTGAGGTGGGAGGATCTGTTGAGCCCAGGAGG +TCAAGGCTGCAGTGAGCCAAGATCATGCCACTGCACAACAGCCTAGGCAACAAAGCAAGA +CCCTGTCTCAAAAAAAAAAAAAAAAAAAAAAAAAAAAACTGGGTGGAGCAGATGGTGGCA +CAGTGTTTTAATGACTGCCTGGTGTCCTGGTTAATGGTAGACTTCTTCTTCTATCTGGCA +GATATAGCCAGGATGGAAGAGGAACAAAATAATAAAGAACCTGATATATATATATATATC +AGGTTGGAATATATATATGTATATATATTTCAAATATGCATATATAGTTATTAATTTAAG +AGATACCAGACTATGTTGAGTAAAACAAATGTGGCTTATCTACCTGGAACTCCAATTTCA +CGTTAAGATTAGGGGAAAGATTTAACCGAATGCAGAGATGCAACATTTTTAAAGGTGAAA +CATGAGACCTCAAAATAATGAATGCTTTGCAGTGGAATACTGAAGTTACCTCCTTCAGTC +CCCCTGGAGATAACCTTGTCTGCTTTTAATCTAGAGGATCATCACTTGCAAAGTGTGAGA +AGCATTGCCCTAAAGCATCAGTCTCTCTGGACTGTTTTGAACTATAATGAGCATATTCTC +CAGAATTTTGGAAGGCTTGCTCTGCTTTTCTTTGATTTTTGTTTTGTTTTGTTTTGTGTT +TAACATGGGCTTTAGGATGGTCTCTTGATCCTCTGATTTTGAGGACTAGTGTTATCACCA +TGAAGCCCTCGTGTCATCTCTTGTCTCTAGGAGGACAAGCAGAAGACATTTCTTCTGTTT +GGCATAGTCCGTGCTCTTCTCCACTTACTCTGATGCCACCTATCTTTCAATGTCTAGCTC +AAGTTAATTTCAGGTCATATCATTCTCTTGACTTTTTAACTCATGTTAAATCTCTCTCTC +TCTCTATCTCTATCTCTCTATCTAATATGTATAGATCTCTATATCTAGATAGACATATAT +AGTAGCCAGCACTGCCTGTGTACTCAACTGTACTCCACCATTTAGCACCTCATTAGATCT +TATTGATTTATATACCCACATACACATTCGCTTCATGTTTACTGTATTCTGACTCTTTAA +GTGGGTCACTACTCTTTAAGTGGGATGATATGTGAGAGAGCCACCACACTTGCTAATGTA +TAGTAGGAATTCACTAAAGACTATATATTATATTGTTTTTTATTCCTTGAACATACTCCA +AGGCAGCAAATAAATGATAACATGGTTCTAGCTAATTAATTGATTTGAATATTTTAAAGT +CATGCACTACATAATGATGTTTTGGTAAATGAGGGACTATTTATACTACAGAGGTCTCAT +GAGATTAAAATGCTGTATTTTTACGTACTTTTTCTATGTTTAGATAGATTTAGGTTCACA +AATACTTAACATCATGTTATAGTTTCCTATAGTATTCAGTATAGTGACATGCTATACAGG +CTTGTAGCCTAGGAGCAATAGACTATACCATACAGCCTAGGTATGTGTAGCAGGGTATAC +CATCTAGATGTGTGTAAGTACACTCTATGATGTTCACATAACAACAAGATCACCTAATGA +CACATTTCTCAAAATGTATCCCTGTCGTAAAGTGACACGTGACTGTATTTGATTACCGTA +ATGTTTTCTATTTCTTGAGCACATTTATCATAAATCTAATGTTTTCCTCTGTAAATTAAG +AGACAACTAGCAAAATTTAGCTACTGTACTTGGGCAGCTTATGCTGCTCTCAGAAAAGAA +ATTGTAGAGGCAAAATCTACTCTGAACTCAGATACTGAAATCTCTCTCTTTTTCTGTAGA +CTATATATGAGAATTTTTTTCTATTTCTAATTAAATATAGGAGGTTTGGTATGTGAGGAA +ATAAGAATCTGTTTAGATAAAAAAGGCTATCCTGATATATGTTCAACACAGCATTATAAC +CAACGGAAAAAAGAATGAAAATATCATCAAGATATCCAAGTGGAAGGCAATTAAATAAAA +TATTGTATAGCCACATAATAGAATATGTATAGCTATTAAAGTAATATTTCTGAAGAATAT +ATAATGAGAAAAATAAACATGGAAAACATAGTAGTAAATTTGTTTAAAGAATGATATGGC +AAAATGATTTCAATGTTGTGTATGTTTTTAGGATGTTGAGCTCATTGTATTGTATTTAAT +TGAGGCTAAAAATTTAGGGCTGCATTCCTGTGTGGTCCAGGGACAGAACTGCCATTGAAT +GTATACTCCGTGTCAGTCATGGGGAAAGAGGTGTCAGGGAACTTAGGCAGGTCCCACTCT +CTGGTCATTGCTCTCTTTTGTCTGTGCTTCTGGAGGAAGAAGGAAGGTAGCCTTGACCAC +ATGGTATTAAGCGAAGTCAGGCCATCTCTTTGGAAGCAATAAGCTGAAGATGAGTAAATT +ACACCTTGTAAACTATACCTGTGGCTTTAAAATTTGCTTTAAATCGATCCACAGTGAGAA +ATAGATTTTATGTTGGAACACAGTAAACACACACTTATCCCCACACACGGCCAAAACAAA +AGCTTCACAAAACAGAGCTTACACTTTCTATGTGTTATGGCCTCTGATATTTTTTCTTCC +ATTATATTCTTTTCTCTTATTTAACAACTAATTGGAAAGTATATACTGATTATGATCCAC +AAATTATATGTAGCATTGTTTTTGAAACTCGAATAAGTGGAAAAATACTGTACCAAACAT +TGCATAATGTCCTTTTTTAAATTGAACATGAAGTTTTTGAGATAAACTGTTGTATAGTAT +TCTAGCATATGAATATCTCTTCAGCCAGCCTTCTATTCCTAGGCATTTCAGTTTTTTGGA +TTTTACACTCTAAGGTTCTTGATTGGTGTTGTCAAATTGTCCACCAGAAAGATAGAGAAA +GATAGTTAACAATTTGTACTTCTACCAGCATGTTATGCAAATATGCTAGTCATTATCCTC +ATCAATACTGCACATTATATTCTCACATTTTCTTACACTAAAAGGCCTTAGCAAATAAAT +GAGGATATGGAGTTTAACCAAAAGAATAATGACAAAATTATCTTATTCCCACCATCTGTT +TTCCTAAGGTTATAATGTTTTAAATTTGAGATTGATATAGGGACATATTTGAAGGTAAAA +ATGGCATTTCATTTTTTTTAAAGATGCATTTATTGAGAGGGTTGATTTTTAATATGTTTC +TTGGCTATTTAAATTTCTTTATTTCTAACTGTAAGAGTTTTAACTCCTTTGTACTTTTTG +CCTCTTGGATTCTAACTTTTTACTAAAGCCAAAAATTAATACTTATTTATATATATGTAA +TATTTGGACCTTTTACAAAAACTCCATTTTCTGTCAGCATAATCCATTCAAAATATGAAT +ATCTTTTTGCCATAGAACAGATATCATTTCAGAGACTTTTCCACACTCCTCATTTTGTGG +AAATGTTATGGATTTCTGCACTGGATTTTGGTGGTAGAGACATAATCTTAGGGCTGGGAA +AGATTCATCTGAGTGCCTGCTTCTGTCTTTTGTTCCTATTATAAGAACTTGGCTAAGTTG +TCATTTACTCTCAGGCAAAGCATCCTTTCCCCTTAGAATCAGTCCCTTTGAAAAAAGTTG +AATCCTAAAACATAATTCCTTGTATAAAACTGCTGGTATGAAATCTGCTCTGGTTTTAAT +TCACCAGTCTAATTGGCAGGCTGGTTTTTTGTGTGCCATTTAAAAATTTCAGAGTTTCTT +TTCTTACAAAAGGGGAAAATGATGAAATTTGTTTCATAAGCATAAGATTGGAAAAAACTT +ACTGAGATCGGCAGGTTGTAAATTTCTTTTCACCTTGCTAGGAATAGATAGATTCATATA +GTATCTATTCCATGAAAATTAAAGATGTGAGCTGAGGAAAAAACAGAATTGGTTTCTCTT +TGACCTGCTTTGAAGCTGACTTCTAAAATATTAAATGAAGAATTGAACTAAGTGTTGCTC +CAGTACAAAGAAATAGCCCTTTTGTTTCAGAGAGTTGATGTCCATTGAGAAGTCCAGCTG +CCGACATTATCATGAGGCCATATCTGCACAGTGATTTTTCACCGTCATATGTGGCATTTT +GTTGCTTTCCTGTTGCTCCCTTTCCTTCTTGGAAATTGTAAAATGAAGAAATCAAGTACA +CTTCCAGACAATTTCTAAGCGTGGTCTGGAAACTTGTCTTGTGTTTCAGCAATGTTGTCA +TGGTTCCTCTATAGTGATTCGTATGAAGGAAAAAATTATAAACTGGTAGAAAAGATTAGA +CAAGTGTAAGGAATATGAAGCCTGCCGAGAAGTTAAAAGACTGTTCTAGAAAAAGAATTC +TATATTTCAAAGAAAGATATTTTAGTGTGTGCATAGGTGCCAGAAGACATGAATGTGGGA +TGTGTAAAACTATAAATTGTCTGCCAGATATGGAGAGCTGAGATTTGTAGGTCATATGAA +GGTTATACTAAAGGGCCTCAATCTTTTTGAAAATGACATTCAAAATTTTTGGATTCCTTT +GTGGGTCAGAGTAGACTGAGGTCATTCATATTGTGGACCGTCTGCATGCTCTCTCAAGAG +AGAACAGAATCCAATGTGTGTGGTCTGCATAACTTACAGAAGAAGATGTGTGCATGACAT +AGAGAAAATGAGTTGGTGGCCAATATGCTAATCTGAGGTTGGTTGTTGATGCCTGGGCCA +CTCCATATGGGTTTTTATTTCAAAGTTTAGAAAGACTAATCTTATATGAGGTGTTAGGGA +GCATACTCATCAATGTGGCTACTATCTGGCTCAGAATCATGTTCTATTTAGCCATCACGG +GAGACAGTGCTTTTATAGTGCCGAGCATGGTGTGATGCATATAGGAGTAGTTACATGCTT +GTTGAATTGAACTTTGTGCTATATTTTTACAGATAATACTTGTAGCTGATATTTATGAAG +AACTTACATGGTGTCATGCACTGTACTGAAAGCTTGGACTGTGTTGGTTCTTATAATCCT +CAGTCCTATCTTATCCTTACTCACCAGAGTAATTGGAGCCTGAGGTTAAATAATTATTCT +AAGTAAGTAGTGCAAACAGGATATAAACCCACTCTGACATCTACGTTCCACTCTTAAACT +ATTCTATTCCTCCCCTAATTTTATTTGCAGCATATGGAATAAGACCATAGTGAAAACCTT +TTTTAAAAAATCAAATTTTTGATTTGGGCTGTGAGCTACAATACTATCATTTTGTTATTT +AAAAAGCCTTTCATCTGAAATAACCTCAGAAAATTGGATTGTGTAAACAGAGTGTATGGA +AGGTTGAAAATACATATTACGTGATGAGTGTCTTCATTCAGGGATAAGAGAACTGATCAA +CAGTGTTTGTTTCCATTCTTGCTTTCTTTTCCATTAACGTGTTCATATAAATGGAAATAA +GCTGTTAGAAATCATAGAGAGCGGAGTACATATTGTATTCATCATGTAAAAAACAGAATA +ATAAGTCAGCAACTGTTGGCTAGTTAACAAAATCATATTCTTGTGGGTGAGGTGTTGAGA +AAAGTAGTTAGTGTGATGCTTTTGTTTTGTTTTTGGTTTTTTACAGTATCAATAACAACT +GTTATCATATAGCCAACTGCCTACATGCTGTCTCTACTTGGATGTCTAGTAGGCAGTTTA +AACTTAATGTGTTTATTATAGAACTCTTGATTTCTTCTTCCTAAATCTATTCTGCCTCTA +GTATTTCCCATATCTGTAAATGGCAACTTATATTCATCTAGCTGCTGAAGATGAAAAATC +TAAGAATCCTCCTTAACTCCTTTATATCCCTCACAACATATATTAGCAAGTGCTGTTAGC +AAAATCGTCAAGATATATTGCAAATCCAACCACTTTTTACCTTCTCCACTGCCAACAGCC +AGGTCTCAACCAGCTGTGTCTCTAGGCTAGACTCCCGCAGTATCTCCTAATTGGTCTCCC +TGCTTCCTACTTTTGTCCTACTATCAACATCATTTATATACTATATAATATAAGCTATTA +TAAAATAGAGACGTACGTAACATAATAATGTATGTGTGTGTATAATTTAAAAAAATCTCA +GCCAGTCTGACCCTTTCCTTGTTCATTTTTTCTCGTAACTTTGTGTCCATTCAACATCAT +ATGCTAACCCTTACTACTGCCTGGAACTTCCTATCTAATCTGGCTCCTGCATGCCTCTCT +AACCTCCACTGTCATTGCTCCCACCTTGCTCAGTCCTCTCTAGCTGCACCCTTTTGCTGT +TCCTTGTAACACTGTTTATTCCTGCTTCTTTGCTTGGATCTGCATTCTCAATATCTTCCT +ATAGTTTTTTCCTAACTTTTATTCAGGTCTCCACTTAAAAAACCTCAAAGGGGCCTACCT +GACCACCCTATTGAAATGCATCCTCTGAATTTTTTATGGGGATTATAGTAAAAATATTTA +CAAACCGGGACAGCACAAATACTGACCAATCAGAAGAGATGACAATGGTTTTACTCCTTA +CAGGCCACTTTCTGACTATCAGACTATAACTGATATCTCATAGGTTATATATTTGCTCAT +TTATTTATATCTCTTTTCCCCTCCAGAATACAAGCTCCAAAGGGTAGGAACTGTGTTTCG +TAGTGCCCATAGTAGAGCCCCATAAACATTTGTTAAATGAATGAATGAACCGTTAAACAG +AGATATATTTGTTTGACCATAACCTTCATATCAAAGATTATTGCTCTGATATACACAAGG +TCTTTGGGGTATTGGCTGTGCTGGAGGCCCTTAATCTCTTAAAGGTCCTTAACCTTTAGC +TTTATTTTTCAATTAAAAATATTTTAAGGTACATAAGCAGTATAATAAATACACGTGCAA +CCACAACTTATAGGCCGGGTGTGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCT +GAGGCAGGAGGATTACTTGAGGTCAGGAGTTTGAGACCAACCTGGCCAACATGGCAAAAC +CCCATCTCTACTAAAAATACAAAAATTGGCCAGGTGTAATGGTGTGCACCTGTAATTCCA +GCCACTTGGGAGGCTGAGGTACGAGAATCACTTGAACCCAAGGGGCAGTGGTTGCAGTGA +GTTGAGATCGTGCCACTGCACGCCAGCCTGGGTGACAGAGTGAAACTGTGTCTCAAAAAA +AAAAAAAGAAAAAAAGAAAAAACACCAAAAAAACCTCCACGACTTATGATTAACAGTGGT +AATGTTATATTGTTTTTGTTAGAATTAAAAAAAAAAAGATATCACTGACAGAGTTGAAAT +AATCTTTGTCCCTATTTCCCTAAGAAGAAATCAGTATCTTGCATTGCTGTATTTCCTTCT +AGTCCATGCTTTTATGCTTTTATACATGGATTATGTGTTCAAAAATAACACATACTTTTG +ATTTTGGATTTTTTTAATGTTACCATCCTGGAGAAAAAAAAAACTATTCTGTAACTTGCT +TTGTCATTCAATGTTATATTTGTAAATTATCCATTTGATCTATATGATCATGTTAATACT +ATATATATGTACATATGTATGCATATGTATATATTTTATTGTATAAATACATAACTCATT +AATGGAAATTTAGGAAGTTTCTTTTTTTATTTTTAGTTTTTGCAATTACAAGCCACTCTA +CAAGAAATATCCTTGCACCAAACTCTTGGTGTGTATGAGCAAGTTTTATTTTGTTTTTCC +CAAGGAATGCACCCCAAAGACAATCTGTTGGACTGTAGAGTATGAACATTTTCGTCAAAT +GGGGATGCACTACTTTGAACTCCTATCGACAGATTTTAAGTATTCTCCTTAATAAGTTTT +GTCGTGTTTATTGATATGCTTCCTCTTATTATGTAATTACTATATTAAGAAATCATGTTT +CTCTTATTTTCTTAGCTGTCAGGAATAGATTTTATGATGTATCATGGTAACCACAATTAA +CTTAGAATTTTTGGTAAAACTCTATGTACTATGCCTCTTAATGTCTCATTTTTGTTTTAA +TTATTTAATAATAAATCACTTGGAAGTTGCATAAGCATCACCAATAAATATTTAGAATGG +CAAAATAACAGAAAGAAGCATGAAATTTGGATAAATAAACATTGAGCTAAATTATGAGCA +AATTTCTTTGACTAGAACTTTACACAGGGGGCAACAAATTTTAAGAGTGGCACCTTACAT +CTGGCCACCCGAATTAAAAGATATACTCTGACCTATACAATTTGTATAAAAGTCCTTCTT +TTAAAATTTTTAATACTTAACCATATGTAATTTTTTTCCCAAATTTACCGTCTTCATTAC +TAGACTATAACAATAGCCTTATAGTGCTTTAAAACTGGAAGTCTTTTTGCTTACTTTGCA +AGATGATATATAAATATTGCATCATCCATCACTGGAATAACTTGTCTCCTAGATTAAAAC +CTGAGGGTGATGTGTAACTGTAATAAATTTGGACAGCAAGGAAGGGTTCTATTTCCAATT +AAAACCACAGCCAGGAAGTTTACATTTAGACTGACAAGGGAGGTAGATCAGTACACATTT +TGTACATCTTCTTGTTTGTTCAGGGGGAATTGGAGGATCTTTTAAAAGTAGCAATGATAA +GTCTTTACATTTCTTTATGACCTCATAAAAAAGAGTCAATTGTCCCTTCTTGAAAGGAAG +TTTCTGGGATCAGAAGCTTTTTGGGTTTTTAGACATTTAGAGCCAAGTGTTCTGAAGTGC +CATGTCTAACATGGGGAAGTGCATACCTTTATGGATATTTTATTTGGATTTAAACAGGTC +TGAAGGTTCAAGATGTACCTCAGTCAAGTTATTTTACTTCTTTGTTTTGAAAAATAATAA +GATGATGTACTTAGCACAGGGCCTGGCATATAGTAAATACTCAATAAATATTAATTATCT +TTATCATTGTGATTATCATTTCTCTTGCTAAAATGTACAAGTCCTTCTGATGCTTATTTT +CTGCTTTGAATGAATCTTCTGAAGGTTTTCCTATTAGTTTCCCTTTCTGAAATGTGTCTG +GCTTTCCTGGATGTTACTAATGGCAGCTAGTAGCTAACTGCTTGTGAGGTTCAGGCTCCA +AGTAAGGTATTTAAAATCAAAATAATTTCACAACTGTGATTTTAAATTAAACGAAGTGTA +TTCTAAATAACACAGAATTAAAATAATCACTCATGGATACAATGACATTTGCACTGAGAT +TATATTGGCTCGGTGTTTTAACAACTGCTTTAGAAATGTCTACGAACGATGTAATAACTA +TTTCTGAAAACAAAGAAAGCTAACAACATAAACAATTGTGCAAATAAATTAAAGCTCTTT +TTATTAATGACATATTGGAATAGGCTCAATATGTTGGCTCTCATAAAGGCATAGCAAGTG +AGAGGAATTCCTGCTGCATGGGAAATGGAAATGCTAGGTTCTAAATCAATTATTTTGGCT +GCCATATTATCCATATTATCCCCTTCCTCAAAAGCATCCAATGGATTTCCGTCACACTGC +TACTCAACAAAACAAAACATTATTAGATGGAAACTTAGCTCCATAATTTCTACTTACTCC +AGTTGCATTTTTTACTTCACAGTGTGTTCAATTAGAGACAGCAACAAGTTGCATTATCAA +GGTGACTGTGAATTAAAAAGAGGTGCTATTTCCTTCCAATACATGTAGCTTTGTACTGTG +GCTTGAGGAGGGGAGAGCAGGCTGGATCTCAGCCTCCACCTCTAGCTTGGTTGGACTTCC +TTGTGCTGGTCACAGCCTGGCCAACAGTGCCTGCTGGTCCCAAGCACCATGCAGGCCTCA +CAATTATAACTTGATTTTGTGCAGGACTCATACTACATTCTGGAAAGAGAACCATGAAGG +GTGAAAAAGCTGTTGTAATCCATACAGAAACTTTATTGATGTGACCATTGGGTGATAAAA +GTAACAAGTGTTAGTAATTTAACTTACTGAGTACCTGTTATGTGCAAGGTACTGAGCTAG +AGGTACAAAAATGTGCAAAACAGACTTATTTCCTAACCTCTTGGAGCTCATAGCGAAAGC +AGAGAGAAATACTTAAATAAGTACACCAGTAACTACTACTGTGATAAACACTTCAAAGAA +GAAATTTAAGCTCCTATGAGAGTATGTAATCTTAATGCTGGTGATGTCAGGAAAGTAAAG +ACCATTGTTCTTGAGGAAAATATGAACGTTGTCAAATGCTAGATTTGTGCAGTAATGGTT +TTGGTTTTGCATCTACATTTTTACAGCTGTTAGAAACAAAACGCTTGTTCCTCAGTGCCA +CAAAGAAATAGCACTCAAACATAAATTTAATTTTCTCAGCAAGGCAATTTTTACTTCTAT +AGAAGGGTGCAACTTGCGACTGAATAATGGCGAGAGCATACCTAGACAAGGGAGGGGAAG +GGGTTCTTATTCCTGACGCTGTGTGGTTCCCCTGTTGGCTAGGGTTGGACCGCACAGTCT +AAGCTAATTCCGATTGGCTATTTTAAAGAGAGCAGGGATACGAGCCAGAGTGGGGTGAGT +AGTTTGGCGGGAAGGGCGGTTACAGAACAGGTGACTCAGGATGATTCAGGTCAGAGAAGG +TGACCAGGAGTGACTCAGGATGGAGCAAGTGACCAGGGGTGACTCAGGTCAAAGCAGGTG +ACCAAGGGAACAGATGTGAACTACTGATTAGAACTAGCGGGAAAGCTGTTTACTGAAACT +AGAGGCAAGGGGCGAAGAGAACCAGGAAGTTAAACTTTAAAATGGAGAATCAAAGAATAA +GAGAGCTGAACATACTGACATACGGATTCTTTGAAGAGAAACTTGGAATTCACTATATCT +AACAGCGTTTAAGACATGCAACTTTATTATTAAAATTCCTACATTAAAATAGCTTTGCTG +TTATAAGACGAAAAATCCCTAACTCCTTTTTGTCACTGAAACTATGTTTTTAAGTTAATT +AAAGAGCAAGTTTTCTTAGCAATGCAACTGCCCTCTTGTAGTAGGTAATTCTCCTTAACA +ATGCACTCACCATTTCATTTTGTAATTATTAGTTACTAGTCTGCCCCCCACATCAGATTG +TAAGCTCCTTGCAGACAGAAATGAACCTGTGTTCTCTATTGTATCCCTGGCAATTAAGTA +TAGTGCCTGATACATAGTGAGCCCTTAATATCTAAGCATGGAATGAAGAATCCTTCTACC +CTGTCTGCTTTCCTAAATTTCTGCTCTCCACTTTCACTCTTTCATTTTAATTATTGTCCG +TCAATAATCTTTTCTGCCACATTTTTCTTATTTCCAGTGACTTTGCCATTATTTATTATG +TCAAAGTAACCTCATGAAGAATCTGGCAGAAGGTGATACTTGGGGCTGTTTTGTGGGAGT +ATTTAGTGGTTTCTCTCCACTGTGAAGTCCCTACGTTGTGTTCCCTAAGTGTTCTCTAAA +CAGTTAGTTTAGTGCTGCATGTATTTATGAAATTCCTTGCTCTGTAGAGCCCTGGGCTGG +GCATAATGGGAGATAACAATGACAGACTGGCCTCTGCCTTCAAGAAGCTTTATAAAGTCA +ATAATTATTTACAAAGAAGAAACAAATATTATGCCAGCACTACATGTAAATAGCAATGGG +AACACAGAAAGAAGCAGTTCATTGCAAACTCAGAGGGATCAATGATAGCTTCATAAAACC +AGAAGGCCTTTGAGCTAAGCTTTGAGAAAAAAGTAGACTACTCTAAGCTGGAAGAAGAAA +TAGAAGGACATTCTAGCTTAAGGAAACTGCAAAGTCTTGTATTTCGCTTTCCTTTTAAAA +TAAGTTTCTTTTGTAGATTTATCTCAACAGTAACAAATGTTACCATTGTGCTGTCTGTGA +ATTAATGTAAATCCTGCTCAGCTCTCCTTGTGTTTCCCAATACATAATATACTACCATCG +TTTCTTATACTTCGCTTCATCTCTCTATAAGCAATCTTTAAATGCAATAATGTAGGTGAA +GGTACTTTATAAAATGCACAGTACTAGATAAAATAGGAGGAAAGTGGTATACAAAAGTAA +GTTGCCATAATTCTTATTTTGTATTTATTTGCAAGCTCAGTGATCACAAATCATAAGTAC +TTAACAGATAATATAAAGATCCAATTCAAAATATATTTACAAAAGCCTGATCAAGTAATT +TTGGACAAGTCACTTATTCAAACTTTCTGGGTTTCAGGGAGTTTTTAATTTTTTTTTTAT +GAAGATTATCTGAAACAATTGACTGTGAAACCAAAAGTACAAGAAAAAGTCACTCTTAAT +AACATACCAGACCCTTGGATTGACCCTGGCCTTTGCCTATCAAAAACGTTCTAGAGATAT +GAGACTTACATAATGGAGATATACAATATCTACATAACAGTAGATGGGGAAATATCAAAG +TCACTGGTGCTGTCATTAAGTACCATGGGTTTAAGTGCTTTTATTTAGAGATGGGTACAG +TCAGAAGGATCACAATGACACAGAGTTCAGATACAAGCAACTTAACCTGCTCTAGGTCGT +AATCTCTGACATTCAGAGGACATTCTGTAATCCCAGCCCAAACCTCAGTTTTCCCTCCAA +TTCTCAAATACTGATTCATGACTATATGACAGTTTCAGTGGTATATTGGACTGTTGGTTT +TACCACTGTTTTCCAGTAAGAAAGATTTATAAAATTGCCTAAGTTCTATTTTATTTGATT +TGCCCCTCAGTGTTACAGAACAGATCTTCATAACTTCATGAGACTGTCTACAGTTATCCT +TAGAGTGGCACGAATTTATGCATGTTCACCGAGAAGAACTTTATTTTAGAAGAATCTATC +TGTAATGACAGAACATCGGCATTACCTTTTCCACAGTTTATTAGTAGTGGGGATAATATA +TATTCTATATGATTTATTATTATCAGTGTTAAAATTTCGAAAGTGCCTAAAGTTCAAGAC +CCATATTTATTATACTAATAACTTGTATAATTATTAGTACAAATATAAAAATAATATGTA +TTTTTATATTTGTATAAAAACTTAAATATGGTTTTATGTATCTTTAGTCATGTTAATTCT +AATATGTAGGTAAAAGCCTCATTTAAAAAATGAGGAAACTGAGGTGAAGAGGTTAAATGA +CTTGCCATAAGTCACAGTAACTAATAAAAAATAGTTGTGAGATTGCTGGATATCATTAAG +GTGATAATAATTAATTTTTATTGAGTATATTTCATCAGGCACTGTCTTAAATGCCTAACA +TGTATTAATATAATATTTGAATGAAAGCGTGAGTAGATTTTAGAAAGATGTAAGTATATT +GCCCTTAAGTTTTCCAGTTTTTGTAAAGCCATTCTTTTTTTTTCATGTGTATATTGTTTG +TTAGTTAAGTAAGCATTTGGAAAACAAAACAAAACTTTACAGTCATAATTGATGCTTCTT +ACCTTGGGTTGTCATAAGGCTTATGAAAGGCTCTGCAGAAATAATGCTAGAACAGACTCC +TCTGGGCACTACAGGATGGAAGGCATTGGGCTATTGACAAATTGATACCAGAAGAGAACT +TTGAGGTCTCTGAAGGAAAAACACCCTGTAATTTCACAGTATAACTAAAGGGAGCTTTAC +TTTGAAACAAGATTATTCATGAAGTCTAGCCTGAAATGAACAAGACAATAAGTGTTGCTC +TACTGCCCTCCCTCCCCGCATCCCCCTTATTTCCTTCCTTCCTTCTTTCTCTTTTTCTTT +TTTAAGGAAGTACATCATCAGCACAGGAAATCACTGGTAAAGTCCTCATTTTCACTTTAG +AATCCTGTCAAAAAATGACCTTAGCAACTAGATTGTAATAAAAATAATTTCAGGAAGCTG +TAAAATTATGTCTACAATTAGTTATTAATCGATGAAGTAAGACACTACATCTAGAAGAGT +ATTTTTCTGATATATAAATCTTATTTGTTTTTAATATTCTGGACAGTTTAAAATATTTCT +CTCTCTCAGTAGAAACTTTTCCATATCTGCTTTAACTTGACACTATGCCCCTGTCTACAA +CTGTTCATGAGCATCTCTGCTCCCTTGAGGAAAATAGAAGTGGAACTACTTTGTGGTGAC +ATTTACCAAGGACAACAAAATAAACCCAATAGTAAATCTAGCTTAAAATAATCATATTTT +AAATTGCATCCTGGATAAACATAGGAATAAGCACATTGTATTATATCTATAGCAATATCT +GTGATTTCACTCCTATTTGGCTCAATCCTCCAAACTCAGGACAGGCCCATTAGTCTCTTA +ACCATAAAGGGCTGATTCATAGAACCAACATAGCAAAACAAAATCTGCAGAAACATCTCA +AAATAATTGGATATATTTGTTGAGCTGATGACATTTTGAAAAATTGATCAAATTGGTCAC +CAATTTCAAATATACATCATGTTTTTGACAGACTGAAATTTGCTGAAGCCATTACTAAGG +CTTCCATATGTAGGCTAGCCTTCTTTTTCTATTCAATCTGTACCCATATTTAATGTATAG +TTAAAATAAAACTAACCATTGCAAACAGTTTAATCTGTAAATGCATTATTTGACTCCATA +GTCTTTGAATCAAATTCTTTTTTCTTGAATTTATAGATTTTACAAAGAATGGCAAGAGTA +TTAATATTTTAGAGCATCTTGGTAGGTTCCATTCTGATAATGAAATCCTTTGGGTATACA +TTCCTATAATTTACAGTCTTGGCCACCTGGGAGAAGTCAAACTTGTAATTCATTAGAAAT +TCAAGGAAATTTGGAGAATTACTAGTTCTGAGAGGACTGGCCCTTGGCCAAGCTACACAG +TAGCAATGCTTCCATTTGATGCTTACTCTTCTGCTGGTCTTTCATTATTATTAAAGATTT +AGGGTATACAAGTGCAGTTTTGTTACACAGATTTTCTGCATAGTGGTGAAGTCTAGACTT +GTAATGTAGCCATCGCCTAAATAGTGTACATTAGATCCACTTAGTAATTTCTCATTTGCT +GGTCCTTAGAGCTCTCCTTCATATGTTCATATGAAGTGCCAAGAAGCACCTCAAGCAGGA +GTAGGGAACCTCTAATGGTGAAGGCCTTCATAGGAATAGTTTATGCTGTTACCCCTTCTG +GAAATCCTGAATTTTTATAAAATCTTACAAATAAGTGAGTGGCTATCCAATAATGAAATT +TAAAATGGTAAGGTGTATATTTAAAGCAAGTAGTTTTTACTCTGTCTATTCTCTGACACA +ACCCCCAGGACGCCTTGCACTAGCCTACTATATCAGTCAGGGTTAGTCATTCATTAAGAC +ATCGAATCTTCACTGTAACCAGAGAAGCAGAGCTAGTAGGAGATGTACATTAAGAGATGC +CTCGCAAAGAATTGGTTTATGCTATTGTGGAGGCTGCCTAGGCAACTGAAAAATCTTTAT +GGCAGGCTGTAAGAAAGGGGAGTCTGGAACTCTTGTGCACAGACTAAAGCTGCTGTCCAC +AGCTGGAATTTTCTCTTCTTTAGGGAAGACTCAACTCTGCTTCTAAAACATTTCAATTGA +TTGAATCAGGCCCACTCAGATTATCTAGGATAATCTCCCTTACTGAAAATCAACTGATTA +TGGACTTAAATCACATCTATAAAATATCTTCACGGAGACACCTGGATTAATGTTTGGCAG +AGTAACTGGTGACTGTAGCCTAGACGAGTTGATGCATCAAAAAGACCATCACCTCTACTT +TTTAGGAATACTAAGAAAATTATTTTTAAAGTGGATTATTGATTAAGGCTTCTTACGTAA +AAATAACTTAGACCTAAAGGAAGTAAAAATGAAAGGGAGTTTGAGCCTAAGGAAGATAAA +TAAGTTATTTCTTTTTTTCTTGGGCCACATCAATGTCATGTATGAAAATTCAAATGAGTA +GCAAATTTTAGTACCCATCTATTATTTTATTTATCTTTATGATCATCCTGTGGATGATAT +ACTAGGTTAAGGGAAGTCTGTTCAAAATTGATTAGCAGTCTTAAAAAAATGACAAATGTA +TTAATTACAAGCAAAAAATTTTTGTCACTGATGATACTGGTAAAAGAAAATAATTATTTA +AATGGCAGATTTAGCATCATTAGTATTAATAACCAGATATAAATGGAACATAATTATTGC +TGCTGATAATCTAAACCCATTGGAAGTGGATTAATTGGATAGATTATTTGGTATTTATAT +GTTTTGTTTTAATAGTAGCTATTGTATTGAATGTGATTTTTCTTGAGGGGGAAAAAAAAG +AATAAAAAATGGAATAAAAGTAGCTATTATAAGCTAAGTTCCAAAAACACATTATAATTT +ATTAAGTTACCATTGCTGACTCCATAATCAAATATAGGCAGTCATTAAAGAATATATTCA +AGCTTGCAATTCCCTTTTCTTTCTTTGGAACTCTTTAATCAGAATAGTAGATTCTAGTAA +AGAATGCATTCTTCATATCTTAATAATGGGACCATCAATACTTATAGCATCGTACAAATA +TTTAGTGTCCCAATCCACATTTTAATAAGACAAAATTTTATTGTGCTGAAATCTAGCCTT +TAGTATGTGGTAAAATCAGATTGACTCATCTTATTTTGTCAGGTCAAAACCAGATACAGT +TTTTAGCATGACATTTTCTATATTTCAAATCAATACCATACTCTGTGCCCTTTTTAATAT +TTAAAAATATTAATGGCTAAGTTATTGATGTATAAAAATGCTCAGTAAATATTTTTCCTT +TTCCACCTTATATTTTTTGAGTTGAGTTTCAACACATCACAATTTTTCACCCCCAAAAAA +GTTTTCATTTTTTCTCATTGTATGTGTGTGTGTATATATATATTTATAATGATAACCCTT +GCTCATTTTCCATGTCCATTCTATACTAGCTCTGAGTTTTGCACTTAGATTCCTTCCGTC +CTTCAGCAAACAGCTTTTTCTCTTCCTCCTGGCCTTTCACTGTCTCCTCACAGCCATTGG +CAGACAGCACTGGAAGGACTTTTATGACTTGAGATTCAAGTTTTTCTCTCTCAAGGAGTC +TGGATGACTCAAAGACACTGGGTTCTTTTTCGGTCTCCTCAGCAGCCAGTGGTCTGCCAT +TGTGTGTGCCAGCAGGAGACTTAGAAGCTTCCAGACTGCCCTGTGTGTGGAACCTCCATG +GGGCTCTGTACTGCAGTCGTCCTCAGTATTAGTCACTGCACACCGGCTGCATTTATCGCT +CTAAAATCCATTTCTCTGCCCCTCACAGACATAACTGCCATCCACCCTCTGAAAACCTGC +AGTATTTCTGGAGATTCTGCAGTGACAACTGTTCACTTTATCTAAGTCAATATGTTTGCT +GAAAGCTGACCAGAGTTACCAGCGATTTCCTAGTCTCACATTCACATTGAAACATAGGAT +ACTTTTACCAACAGCCTGGATTTTTTCCCCTTTTTTTTTGTTTTCCTTGGTTTTTTATTT +TTTATTTTTATTTTTTATTTTTTTTGAGATGGCAAGTGAGAAATCTAGGAGTTTTTAGAA +TGAAATGTTAACTTACTTTTAGTCTGTTTTTTATTCTTTTGCCAGTTTGACAATCTAGCA +TATATGCTATTTATTCACTTCAGTTGCTACATGCTATTCAGATAACCACCTGACTACGTA +TGCCAAGCATTTTGCCCCTTGCTTATTTAATCCTCAAACAGTTGTATGACATAGGTATTA +TTATCCTCGAAACACTTGAGAACACTGAGACTCAGAGAGCTCAAAGGGTGTTGTCTATCA +CGACAAAGCTAATGAAGGACTGAGCTGAGATTCATCCCAGTTTCAAAACCTATACTCTGC +CAAGGGAATTCTTGGGGACCTTAGCATAAATTATTAACAGCTAACCTCTGTCAAACATCA +ACTGCATATCAGGCACTATTGTAAGACTTTTATATGTGTTCATTCATAACCATCTCAATG +ATTAGGTACTATAATTGACCCCACTTTTCAAATGCGGAAGGTAGGACACAGAAAAATTAC +AAAATCCGTCCAAAGTCCCACAATTAGCAAAAATCTTGGCAGTCTGGTTTCTGACTCCTT +ATGTTTACCCTGCATCCCATAATGTGTGAAGTTAAGTTGCAGAGTCCAAGACTTAAAATT +GTCTTTATACTGTCACTATAAAAGAAAAGAGGCCAGTGGTTTGGTTAAGACATTCTTGGG +CTGTGGCGAATACTGACTATGCTTTTAAAAGTTGTCTTAAAAGGAAATGGAATTTTTATG +GAATCAACCTGATTAAGAGTTTGCCTTACATTATAGACTCCTTGTCCCACGAGTCACTAG +GGACTCTCATAAATAGAAATTTGCTATGTTATACCAGAAGAAAGATTTAAAAACTGGCAT +TTTTCGAGCAATAGGTACTTGGTAGAATCTTGTGATAGAAGAAAGTAATTTTTCTTGGCA +GACTCTAAAGTAGATAATTTGGCAATGTCCTTCTGCAGTCTATGTGCTGTGAACTTGACT +CTTGAGAACAGCTGCCTTTCTAGAGAAATCACCTCATTCAGAAGAGATGACTTTTCTGTT +TCCAGATTAGTATGAGATTGGTTCAGGAGAGCTCAGTAATGAATTAACTGGTCCACGAGA +ACATCATAATGGCTCTGTAGTAGGAACTGAAATTATACTTCACTTCCAGGCCATTATATG +ATATTTGTCAAAGAATCATGTAGTAGTGTTTCAAGGATTTATTGAGATATATACCCAGCC +AGGATTTTGTTGTGTTGCTGTTTAACGCATCTTAAAACCTCACAATTCACTATTCTAGCA +GTTTTTCATTTTATGTTTTGTTCCTTTTTTCCTTTATGCTTTTTTAAAATTTCTAAACCT +TAGTCTAGGATACAGAAAGACTGGTGATTCTTTAGAAATAACCATTTCAAAGCCCTGGTG +GAAGAGAATTGGTGTTTCTCTCCTTCAGTAATAGACAAATTGAATAACCTGGCTTATTGT +TTGCTTGAGGCAGGGAAGAAGTAAAGGATTGGGCCTAAATTTCTTTGACAACAAAGTATG +ATCCACAACACTTCGCTTTGCCTGAAAAACTATATGCCAAACCCGGAATCCTTCAATAAT +GCTCAGCACACTCAATGCCTTAGAAGTGAAGGTTTTACAGCTCTCTGGTTCTTAAGGAAG +ATGATACCAATCTGGTGAAAGGAGTGTGAGGTGTTTAATAAGTTCTTATTTAGAACAATG +AAATACAGTGAGAAAAATTGTAGCTCTTTTTTTTTTCTTTTTTCTTTTCTTTCTTTCTTT +CTTTTTTTTTTTTTGCCTGCTATTTTAAGGTAGATAAGCAATTCTAAAGAATGAAATGAT +TTCATGAAGAAAATACTTCAGAGTCACACTGAGAGTTTGTTTTGTCCTGGAAGGTAGATT +TGATTTTTAGCATTTCCTTTTCCATATGGAATCCGAATTCCATCAGAATTTTCTGGTCTT +GATTAATGAAAGTGTTACACTAGTCAACACTACCTTTGAGAGAGGAAAGTTGAGTCCTGT +TTAGGATTAATGTGGCATAAAAAGTAATGTGTACTAGATCACATATTCCACAACAGAAAG +ATAAAACAGGATTGTTCTTATTTAATCTTGAGGTTTCAGTCTTCTAAACAAATGGAAATT +ATCACCTTAATCGAATCACTAAATTATTGTTTAATTTAAATAGTATCTGGGTTAGAATCC +TCTAGATTTACTTAATGATGAGTGTTCATGGAATGTTTGCTTTATGCCATATTTTATTTC +TGTTCTTTATAACAATCCTATAAGGTATCTATTGCCCCCAATTTAAAAATGAAGACAAAA +ATAAAAAGCACAGTTACTTGCTCAGGAGCATATTGTTGATGTTTGAGCTGAATCCCTTAC +TCCTTCCACTGTGGAATGCAGCACTTTGGCTGAATGTTTGCCCTTTAGTTTATTGTGCTA +AAATGTGTGTGTGTTTTTGCCTACTTAATTCTTTATTTTCTTGTCTCCCTCCTTCTGCCC +TGATCCTTTTTGAAAGTTCTTTTGTTCTTCTGTAGAAGCCATTAGGTTACTTTTATTGGT +AAAACTCTCCCTGTTCATTCCTCTACCTGCTGCCCACCAAGACTTCCAAAGTGCTCCCAT +AACATGGGGTCTATGCCTATGACAGCAATTAACACAGTGCATAATGATTTCCCATTTGTT +GTGTAGTTCACCTCTTAGAGCAAGGATCTCATTCCCAGCTCCACATTAGAACCTCCTAGG +GTGTTTTTAAGAAATGCCAATATTTGAGAACTACTTTTGGAGATGAAATTTAGAGATTTT +TTTTTTTTTAGTTGTCTACCTAATTTTAGTGCAAGCTGAGAGTTGAAAATTTATCTTATA +AATTCAAGGGCAAGGATAATTCAGCCATATTCCCAGAACTTAGTACCATCCCTGATATAT +AACAGATACTTCACTAATAATGACTGGTTGAATGAATGAATGGATGAATGAATGAATGAA +TGAATTTTTAAATGCTGACTTACCATGGTTTTCGTAATGTAAGTATTTTATTTATTGATT +TGATCATTGTATGATTCTTGAATGCCTTAATGGTGAAATATTATCAAGCATTAAGCAGCA +ATTATAATATCTTCAAATTCGGTTAGTGCTTTACGATTTTCACAACCAAATTGTATTTGC +CTTTTGAAACCTAGCACAGTGGCTCTTCTATGATGCTTCTTAAGAATTCCAAACTCAAGA +AAAATCAGCTTATTGAGATGACTGAAGTTTAACAATAGTGCAATCAGAATGTGAGGGTTC +TCTGCAATTTGATTTGGGACTTGAAGGATCTTTATCTACTGGTATGTTATATCCTGATCA +AACTTTGCATCAGAAAGCAAGAGGCATTTTAGAATTCAACAGCCTGCAAAAGGATCCTGG +CACCAGCACACAGCAGGTAGTAACCTGCCTAGGGCAACTTCATAGGATAAATTGTTTGTT +TCCCTAGGTAGCCATCAGGATATTACTAGATTTCTTAGAGCCATGAGAACATTAAGTGGG +GTTTTCAGGACTATAATATATCCTTCAGCTCTCATTTCAACGGCAATCAATGTTCATAGC +CCTCCTTTCAAAGCACTGGCAAACATTCTGGTATAATTAATGTCACTGAGGTATTGTTTT +TCCCATTGCTTTCTGTGTGTTTTGTTTTTTTTTTTCTAAGAAAGGCAAGTTACAAGACAG +ATGTCTTATATGAAAAGCTATTATGCTATTATGTAATTTGAAACAAAAGGCCAGTCTCTA +ATAATAGTGTGGGTGTTAGAGGGCACAGAGTGAATTTTCTTGAATGAGATAATTTATGGA +AATTCTCTAGGACACCATATTTCAACTTGGCATAAAAATTCCAGATTCATTTAACATATG +CATGGTGAGAACAACTAAGTTTTAAGGCCAGTTTGGTAAAGATTCATAACTTTGTCAGTT +GATTATGTCTCTGCATAGGATCATAAGTAGTTTTAGTGTTGACAAGTACAGATTCTTGCT +GGGGGTTGTGTGAAGTTTAATTCAGCAATTCAGTACAAATCAATAGCTACTTATTGAGGG +CCCACTGTTTTCACCTGGGTATTTTGAGGAGAAGGCAATTGGGTAAGACAAGGTTCCTAC +CTTCAGGGAACATATGGGTAGTTGAGTAAAATTTCTACTATTGGGTAGAAAAACTGCAGC +TTTTGATTATAAAATAAAGTTTTGTTGCCAGTAAATTAGGTCTATAGAATAACACCATGG +TAGGAGAGATTGATTTAGGGAGAGTTAAATGTTTTCCCATTTCCTATGAGTATCTTTCTT +TTCTTTCAACTGCAATCAGCAACTTATTTGATAAGGGAGGTTTGGAAAATTATGTACATT +GTTTATTTCTGAAATTAAAATAAAAATATGCATTTTCATAGACATGAAGAGCATACCTTT +ACTCTTAAGTATCTGAACACAAGATGCTTTGGAGGAATAAGTTCGCTGAATTAATCTTTA +TAAATAACTCAGTTGCATTCATCCTCAAGTAAGGAATTCAAGGGTTGCCTTTGCCCATCT +GTTTGACAAAGTATGAATCTTAACATCACGGTTAAGTGAATTATCTGACAGGATGAACTG +CATATACACTTACAGTGAGGCTTAAGGGTGCTGTGATACTTACATGAATTGGAGTATTTT +GAAAATGTTCAGGTTGACTGCAATGCTATATTATGTTAGGAATTGACTAACATGGATAAA +CGGAATGTGATTTTTTACAATCTGTATTTTCAAAGGTTTTTGATTTTCATTTACCCATCC +AGGTTGCCCCCAATACTACCAGTTTCTCCTCATCTTTCATTATTTCACTCATTCCTTTAT +GTTATTTGCTTAGTTTGGTGTCTTTTTATCTCTCATATAAACAAATATACGTAGTCTAAA +GCAAGGTTTCTCACACTTGGCATAATTGACATTTGAGACTGGATAATTTCCTGTTATAGG +TGGCTATCCTGTATAGCAGCTTACTGGCACTAGATGCCAGTAGCACACACATCCAGTTGT +GGCAAACCATCATATCTTCAGATATTGCCAAATATCCTCTGAGGAGCAAAATTGCCCCAG +TTGAGAACCACTGGTCCAAGTCAACTTCCTAAATCTTCTTCTTCAGTCTCAACTTCCTTC +ATGATAGCTGCTATTCTAATGATTCTAATGCATTATTTTACTGAGAATCACATGTCTCTC +TTGTGCCACTGAACCTCCAATGACTCTTACCATAATATTCGAGGCCCTAACTGCCCTTAC +CCTGTTTTATTTAAGTTTCATTTGTAGCAAAATACTACATGCTCATGTTAACAAATGAGA +GAGTACAGAAGAGCTATGAAAAGCAAGTCACCTGGTCTCCTTCTCCCCACTCTCATGTCT +AAGAAGCAACTTTTTTTTTTTTTCCTGAGACAGAGTCTTGCTCTGTCACCCAGGCTAGAG +TGCAGTGGCACGATCTCAGCTCACTGCAACCTCCGCCTCCTGGGTTCAAGCAATTCTCTT +GCCTCAGCCTCTTGAGTAGCTGGAATTGCAGGCACTCACCACCATGCCCGGCTAATTTTT +GTAGTTTTAGTATAGATGGGGTTTCAGCATGTTGGCCAGCCTGGTCTCAAACTCCTGACC +TGGTGATCCGCCTGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCGTGAACCACCGCTC +CCGGCCTTAAGAAGCAACTTTTAAAGAACTGTTGCTGATTTGCTTCTTGCATTTTTCTCC +ATAACTCTAGATATGTCTATACTTTTGTTTGATTTATCAACTTTAGGCAACATTGTCTCT +CTGTTTTCAAGATGAAGTTTTAGATCAGTTATATAAATTGCCTTTTTTCTTCCCTTTTTT +CCATTTTATGATATTTAGGTGATTGTATTCATGTATGTTGATCTTGTAAACATAATCTAT +TATTGGTCAATCAACTTTCAGGACCACATTGTTGTACTTTCTGGAGCTAGGAGGGACTAG +AGACCCAATTGATTGTATCTCTCAACCCTCCCATTATAGTAAGTTGAGAACTTGACTGCT +TTTACCTTTTCTTCACCTCTTCCATATCCTACCTGCTGTCAGCCGTATTTTTATTTACAC +TACTATTCACAGTGTTAAGATTTTTATTCTGCCTTGCAAATGCAACTAAGTCTTATGTCC +TTTATTCTTAGGTTAACTCTTTAAGTTGAAAGTCATTAAACCAAATTTACATTATCATGA +CTCTGCAGACATTTTTCAATATTACATCAAGTTTAGATCTATAATTTTATTTTATTTTGC +ATAGGTCCAAAGTCATGATCCTTGCATCACATGGAGTATAATGATTAGTATCAGTGTCAG +ATAAATTCTTTTTTTCTTCAATTCTTATCAGCTGTGAAAAATCATGCCATCTTTTACAAG +TAACTCCTATCTTTCTTGTGAGTTTTCATTTGCCCCGTTTCTTGCACTATTTGCCTATTT +TCCTTCATTATAGCCACATGTTTATGAGGTCAGTCTTTTCTGGATCCCAACCCACCACCT +GGGTTTTTTTTTTCATTGTTGTCCTAGGTAGGACCCATAGTTTCCCGTGTCTTTCTAGTT +TTTGTTTTATCTTCATTTTGTTAGGACATAGGTTCAATTAACTTATAAAGAAAAAGTGTA +TGGGCAGTCAACTTTGCATGGGTACTTGCTTGATGAAAAATTTTTCTATTTTACTCTCAC +CTTAATTGATAGGTTGGCACAGAATTCTAAGTTAAAAATATTTTTGTCCACAATTCAGAA +GGCACAGTTAGACCCAATGCTGCTGAAAAGACATACTGTTTTTCTTTTCTAGGTGACATA +TTGTTCTCTTGCATTAAGTTTCACTAAGTTAAGCCATGGCGACACACAACATAAAAATCT +TAGTGGCTTGCAACATGTTAGCTTCAGATTAACTTTAGCTTGGTCCCACATGATCTAGAC +TGAAGAATTAGCCCCATCTGGGAATGCTCACCTCTTGGCTAGAGAAAGGAGCTGTGGTAG +ATCAATGTCGCTGCTTGGACATAGCATATGTTATTTCCACTCATATTTCAATATGTCCAA +GCTTGACATTAATGTAATAGGAAACATTCTCTCCAAGCCTCCTCCTTTTTTAGCCCTGCC +CTCCCCACAAAGAGAAGACCCAGGGAGGGGCCCTGAAAGATGGGCTCTTTAGAGGGGGAC +AGTGAATAACTAGGAACAATAAGACAATGTACCACACTCTTGAAAGAGTTGAGGACTTTC +TTTTTATCCTGAAAATTAATAATGAGTGTCCAGCTGGTTCTTTTATTCATTTATTATTAT +GCTGGAACTTGGTGGATCTACCCAATCCAAAAGACTTAAACCTTTCTTGTGGGAAATATT +TTATTATCTTTTAAATAACTCTTCTTCCTGTTCTTCATTTCATTCATCCTAGAAACTGAA +GCATCTCAGTTGTTTTTATCTGTATCTTTTATGTTTTTATTTTTTAAAACACCTGTGTCA +TTGTTTTGTCTTTTTGCTCTATGACATTTTTCCAGGCATTTATTTCAATGTATTTTTTTT +AAAATTGACAATACAAATTATTTTTACTGTTTTCTCTCAAAATATTTCATTTTTGTTATA +TGAATATAAAACATTCTTGAACTTCTCCGAGTAGATTTGTTTTTGTTTTTAACCTTTATT +TGAAGTTCAAGGGTACAAGTGCAGGTTTGTTACACAGGTAAACTTGTGTCATAGGGGTTT +GTTGTCTAGATTATTTCATCACCCAAGTATTAAAACTAGCACTATTAGTTATTTTTCCTG +ATCCTCTCCCTCCTCCTCACCCTCCACCCTCCGAAATATTAATGGAATTACTTTAATATT +CTTTTCTGCTTCCTGAGTTATCTCCATTTCCCTTAGGGTGAGCTTTTCTGCTTATTTCTT +TTGGCTTCCTTTTCAAGAGTTTCTGACTAGAAGCATTGTGAGGGAGTAAGTCCAGTTTTA +CATTAGTAAGTTGCATGTCAGGAAATGGTTGTCCAATATGCAAGATTGCAAAAGCTCCAC +TTTAAAACTCCGGTGTACACACAGGAGCCTTAAATTTGCCCAATTAACTCAAGGCCCTAT +TGAAACCCTTGCTTCCTACATACCAGAGAGTGTCTTAGATTTTTCTGTCTGAAGATAGGA +ACCTGGATTGATTTCCACCCCTGGCAACAATATAGGAATTGTAATAAAATCTGTGCTTCT +TTTTGCAAAGCCCATTAGGAAATAAAAATGTATTCGTGTTCCTATAAAATTTTGAATTTC +TCAGAGCTTATATTTTAGATACGTATGGAGGTCTTAGTCAATCCTTTTACTTAGTAAGCA +TAATAATCAAGTTTGTCTGGCTTATTTGTGCTCCTTCTCAGTGTCAATATGAACCTTGGA +TGATTTGATGAAGGGCCCTAAAGTAAAGTCTTTCAAACTTTTTAAATCTAAAATTAATGG +TAATGCATTTTACATCAAGACTCAGTAAGCACATATAAACATAAATATGCATTTAAGTGA +AATAAAAGTTTCACAAAAGTGCCTTACTGTGTACAAAGCAATTTTATGTTTTCTATTTCA +GATTTTAAAACTGTGATCAAGATTTGCTAAACTGGTTTATGACATACTGATAATTTTATA +GTGTAAAAAATAGTGCTATAGAACATGGTCCTGAGAACTAAATAAAAATGTTCTCTAGGT +TTTTAAATAAATGTCACAAAATCTCTATTCTGAATATATTGCCTTTATTTTGTAACATTG +CTCCTTAACTCAGAGGCTTATAATTTTTGGCAGGCTTTGTTATCCAAAATTTTCTCCAAA +ATTAAAGCTTAGGAGGAAACCACAAAACTAAAACATAATAATTGCCTAGATTAATAATGG +ATATATGTGTCCATTGTCCTAATTAGGATAATGTGTGGTTAGTATCGCCTAGATAATAGT +ATCTTCTGTATCTCCTAGATAATATTTCTTATAGCAGGGAATTTACAACATATTTCTCTT +CATCAAAAAGATTTAACCTTTGTTGCTTGATTTTGGTCCACCTCTGTATTTAGAGATCCC +CTAAGGAAAGCCAGAAACCAATGGCCAAGGACTGTGCTGCAGATTCCCCTCCTGCAAGTG +GCCACTTATGCCGAACTCTTTTCTAAATATTTTGGTGAAAAATAGAGTCAATCACACTTG +CACAAGATTAGCTGAGCACTCCAAGATTGATTTAAATCTGGGACTAGCAGAAAAAGGGAT +TCAACAACAAAAATAAGACGTGATATTTTGTTATGCAAGGAAAAGAATTTTGTATTCAGA +GCTGCTTTCTTAGAAAACTAGAGACAATGACAGTGAGTTCTAAATAAAAAATACATTTCA +GTGAAATAACCCATGACTGAAAAGTAACTATGAGCACACCCTTGGTTCACATCTATCAGT +TATGTATTGCATAAAAGAGGGTTTGTTTTCAATTGTTATTAGAGGAATTGAGTACCTTTT +AAGTGGCTAGAAAGTTGTGTAAAGTGCAATTTTAAGTGGCTTTTGTTATGCTACTGAAAA +GTCTTAAGTGTTGGTTAACTTATATGAAAGAGAGTGTGAAACAATCCTTGATAACATTTT +TTTCTTTCAGTAGGGTTTGTGAGGAAAAAACTGTGGCTGAGGATTCTTTTAAGTAATAGC +CACACAAATAATCGCAGATTACAGTGTCATACAACTCCATTAACTCGGTGAAGGAAAATA +ACAACATTTTCATTTTAATGAGATGTCAGCTCCCTCCCTTGCTGTACTGCGCTTCTTAAT +GTCCTTGCTGTCTGCACTGACTTGGGGCTCCAAGGCTCTCTCATTACTTGGCAATTCCTT +TCTCTAATTTCTTGTGACACACGGTGCTTAAATCCACAAGAAATGTGAGGTAAGGCTGAG +AGAATTCCTGCAGACTGATTTACTATATGCAGAACGCTCATTTGCATTATTCATTAGATA +AGAGCACTGATTTGCATCTCATTCTGGTTGCCTCCTTTAGGTGAAAAAAAATGCCAGAGT +ACTCTCAATATTCCCCTGTTTTTTTTATATTAATAATAATTATTAGGGGAATTAGGGTTG +ATTCCTCTCCTGTACCATTTGCAATTTCTCTTTAAAAGAAAACCCAGAAAACTCTAAACA +CTTCTAAACCCCCAAACCAATGTGCATTTTCCCTTTTGTCTTTAAAGTATTTGAAGCTTT +AACATTTGATAAAAGATTTGAATGCATAAATGTATTTTATTGAAATGCAAGAGAAGACAT +TTATGATCCATATCTAACATTAGGAATGGGAAGGAGGAGGAAGCAGTTAAAAAAAGTATA +GGCACAAGTACAGCATTTGAGTCTCCCCAAATCTCATTTTAGAGAGATTTCCTAGCAACA +GAAACATGCCACATGTTTAATGATACTGCCAGTAATAAATTCTTCCCCCCTTGATGGTCA +AAGCCAAGTGAAGAAATTTTGCTTTGCATTTTGTTTTATTAATTGCTTTGTCAATTAAGA +TTATACTTTATTGTAAACATCAGCTCATCATTATTAAAAAGTCATTGATGTCTGACTATG +TGTTGAGCTCTGTGCTGGCACCTAGAGTTCCTGTGTTAGATAGATACAAGAAAAAAAATG +ATAAAATATCCTTCATTCCTTGCCTATACTCAATTCCCCATGGTCCTAGTAAACTTCCAA +TCACTCACCATTTCCTTGGCACAGACTCTGTAGGCTTTATTAAATGTCATCTAGTGATTC +TCTGGGATTTTGAGATTTGAGCTGCACAGGAGACCCGATCTACAATCACACATTCAATTG +GGACCACTGATGCATTCACAAAGGGAAAGCAGGGCATAGCATGGATGGCAACCTTCTTTA +TCCTTCATGAGAGACAAGGACAGAGGAGTCAGAGACCATTCCTCTGTCCGCTGATTCGCT +GTGATTCAGTTGCCCCTTGAATAAATGATAGCATTCTGTTGAAGGTTGCAACAAACCTAG +TGTCATGGATCAATCACAACATCCAAAAATGAAGGAGAATTCCAGTGATATTAAGGTCAC +ATTGTAACCAGAAACATGGGATCTAGCAGGCTGGGATGATTTGTTTTGAGTAGAGGTTTT +GTACAAATTGCACATTGTTTCATCAACACAGGTAACAGAAGACTGAACCGATTCTTTTGC +TCTACTTCTTCATGTCTCCCAGAGCATTTAATTCCGTGCTGGAAGAGGTCATCACAAACA +TTCATTATCCTTGTTCATGGGGCACCCCCTACCTTAACTGCTGTTTATTCTTGTCTGGTT +CCTGTGATTAATGCTGGAATGCAAAACAGCTACTTCTCTTCTTTATGGCTGTATCTGGCA +CACTGATCTGTTTAAGGTCTTTGGCATCCCCATAAGGAACACCAGTTTTGAAATAGCCCT +CATTTGCATTTAGACTAAAACTAGAATCCAGTCCAGGATTTGATTTTCGGGAAGCGATCA +GTTAGATAAACCTCAAATTGTGTTTTTGTTGCAAGGGTGATTATTTAAATATATTTTTTC +TACTTGAAGCATTCAAATATTATCAAGTAATAAAGTTGTATTTCTCTTATTTAATGAGGG +CCAAATGGTCCCCTTTCAAAGTAACAAGCACTAGTATTAAAAATGAGGGGCAGCTTATAT +TTGGTTGTATTAGTTTTGGATGATTATGCCACTTGGAGGACATCGAGCTTTTGTTTTTGT +TAATGTCACAATGGGCTTATAGTGCCATGCTTCATAGAAATGTCACTGCTAAGCTAATTC +TACTATGGAAGTCATACTGAGGTTTCAGAATCCCGAATGAGCTAAGGAGATTGCATTTGA +ATGTCTCATACACATTTCAAAAATAACCTGGACAAAAGACAACTGTGATTTCCTCTCCTG +CACTCCTTAGCCCCCTTCCCCCAAAACTGATTATCTTAGCAAATGGGATCACCTTTCAAC +CAGTTGCCTAAGCCAAAAACTAGTAGTCCTATGTGATCCCCCTCCCTTTTCCTGCCACAA +TCTGATTACTATTGCTGTGTGACAAACTATCCCAAAACTTAGTGGCATAAAGCAGAGAAG +AGCATGTGAGATAAAAGATGCTGTAGTAGCCATCTTCAGTCAGTACAATCGATCTATCTA +CTGCCCACAACTGTTCACAACCTTTCTACATGTAAAATACACCCAGTCCTTCCCCCAACA +TTCCCAAAATCTCACCTCATGACTTTGAAGTCTAGGATGTTGTCATCCAAGTCATGCCTG +GTACTGATGAGGCTCTTTGGATGCAGTTCTCCTAGCATGGCTCCTCTTAATTTCTGAAGA +GCTGTCAACAAAAGATTCCAATTGTCTTCTTCCCACATACCACCATGCACTGGGGGTCAG +GCAAGCATTCCTGTTCAAAAAAGGGAGACATGGGAGACACACAGCAGTCACTGTCCAACA +GCAGTTCAAAAGTCAATTGTTGCCAGATCCACCTTCCCAGCATCTGACACAACTTTCTGA +GTTATTCTTCCTTTTCCATAGTAAATGGCCGGTTGTTGCCACTGAGTAGTTTTCTCACCC +TGCTTCCTGCCGAAAGTAGTTCATGGGCCCAGAGACCTCACCCCCTTCATTTTATGGTGT +ATCTCTCATTTTAGTTCAAGCTGATGGAGTTCCTTTAAAAAAACTTCATGGCTTCCTGTA +TCAATTTATATATCCACTACATTCGACAAAAGACACACCCACAGATCTCTTTAGTGTAAG +CCTTTTTCTACCATGGGCTTCCAGTGAAGCTGCCATGGACCATCACCCTTAAGATTCATG +AGTGCCTGTTGTTTTAAAAAGGCAGGTTCTTAAATCCTGAAGGCTTTGTGTATGTGTGAA +AAGTTTATAAGGAACCATCTTAAATCTTTCCAAAACCACTCCAAAATTTAGTGGCAGAAA +ATATTCATTTATTATACTTAAAGATTTCTGTAGATCAGGTATTCAGACAGGGTAAAATAA +GGATGGCTTGTCTCTGCTCCACAATTTCTAGAGTTTCCACTGGGAGAACTCAACAGCTGG +GGACAAGTTGACATCTGGGATTGGGATCATCTTGAGTTGAGGTGTCTCCTCACGTGTCTG +GCAGTTGATGCTGGCTGTCAGTTGGAACCTCACTGAGGCTACTCACTGGAGCACCTTCAT +GTGGCTTCTCACATGGCCTGGGCTTCCTCACTGTGTGGTGAACTCAGAGTAGTCAATTTG +TTACATAGCAGCTTTGAGCTTCAAGGTGAGTCATAGCAGACAAGGTGTATTTTAATTTCC +TGGGACTGCTGTGACAAAATGCCACAAATTGGATGGCTTAAAAGCATGCATATATCTTCT +CACAGTTTCAGAGGCCAGACGTCTGAAATCAAAGTGTTGGCAGGACTGCACTCCCTGTGA +AGGCTCTGGGGAAGAATCCTTTGTTACAGATTCCTATAGCTTGTGGTGGTTGCTGGCGAC +CCCTGGCCTTCCTTGGCTTGCAGCTGCATCAGTCCAATCTCTGCCTTCCTTATCTTTACA +CGGCCTTCTTCACTCTGTGTGTGTCTGTGTCTGTGTGCCCTTTCTTCTTCTTAGAAGGAC +ACAAACCATATTGGAATTAGGGTCCATCCTAATCCAATATGTCCTCATCTTACCTAATTG +CATTTGCAAAAACCGTATTTCTAAAGAAGGTCACTTTCTGAGGTTTGAGTGGCTATGAAT +TTTTGTGGGACACTATTGAAGTCAGAACAAGGTGGAAATCACATTGTCTCTTTAGCCTTG +AAAGTTACGTAGCATCGTTTGTGCTGTGCTTCAATTGGTTAAAACAGCCACAATCATACT +GAGGTTTAAAGGGAGGAGACTTCCAGATGGGGGACAGCTAGGATCACATTGTGGAGCAAT +ATGCGGCCTGTGAAGTGGCATTGTGTTCATTTTTTAAAAATGCAGTCTACCACATCCTTA +TCCAGTCTGCGACCAACTTCTATTTTTTTTTAAAACTTGTATACGTTTAAAGGGTAAAAG +TGCAGTTTTGTTACATAATTATATTCCATAGTGGTGAAGCTTGGGCTTTTAGTGCAACCA +GCACCCAAATATTGTACATTGTACCCACTAGGTAATTTTGCATCCCTCGCCCTCACGCCC +ACCCTCCCACTCTTCAGAGTCTCCAATATCTATTATTCCACTATGCATGTGCATTATTTA +GCTTCCACTTATAAGTGAGAACATGTGGTGTTTGACCTTCTGTTTTTTAGTTATTTCACT +TAGGATAATGGCCTCCAGTTCCATCTGTGTTGCTCCACAAGACATGATTTCATATGGACT +TTACCTTCAAAATATATCCCAAATCTGTTCACTTGCCTCCTTTGCCACCCAGTCATGCAA +AACACCGTTATCTCTCATCTGAATTATGGTATTAGACTCTTATTTGATCTTTCTGTGTCT +ACTCTTGCCTCTTCTAAACCACTCAGCACCAAGTGGCAATAAAAGAGATACTAAAACTAT +GAATGGACTTATGTCACTTCTCTGTTTAACTCCTTTAGAGACTTCTGATTACACTTAGCG +TAAAATCCAGATGTGTCTCAGAGGCCTAACTGGCTCTGCATGATCCCTCCGAGCCTGTCT +CTTCAACTCTATTCTATGTCAGCTTCTTCTTCCCTATGTACTATTAGGTTGGTGCAAAAG +TAACTGCAGTTTTGTCATTAAAAGTAAGGCATTAAAGTAAAGTACTAACTCTCCGGCCAC +CCAAGCCTTCAAATTGTTCCTGGACCAAGAACTGTTTGTACCTTAAAGACTTTGCGCTTG +TGTTTTCTTCTGCCTGGAAATCTCTTTATTCAGGTCTTTATGAAGCTCACATTTTGCACA +CTCTAAGTTTCATCTTAAATGTTATCTCTTTAGACAATAATGATAATAATAATTAAGTTA +ACATATTTTTGAGTTAGCTCAAAATATAGGCCATGCCCCAGAACTAGACATTCTACCTGG +ATTATCTCTTGCGATCCTTGTAACATCTTATGAAAGAGGTTTTATTATTATCCTTATTTT +ACAGATAAGGAAACTGAGGTTTAGGGATGTAAAATAATGTTCCCAAATCATACTGTTGCA +CACTTATGCAGTATACTGTGTATGATGAAGCACAGAGTTTAGAATTACACACTGGGCTTT +CTGGCTCCAAAGGCTGCCCTCTAAACTACCAGTCTCTGTTGCCTCTAGAGAGAGGCTTGC +CCCTCATTTTATTCTCAGTTATAGCATCTGTTTCTTTTCTTCGTTTTGCCTATTACTCTC +TGTATTTTTTTAAAAGAGTGTATTTATTTGTTTATTGCCTATCTTTACCACTAGTATTGA +AAATTTTTATTGTTATTTTTCATTGTTATACCCTAGCACCCAATGCAGTACTTGGCACAT +AGTAGGTACTCAATAAGTAATTGATGAATAAATTTAGTAATGTGTTGATCTAACAGCTAG +CTTTGGGTATAAGGTCAGGGATGATTTATAGCTTTTTAAAATTTCCATACTCTTACCACC +AACCAATTTCAAGTTGCAAACAGTTTAACAATTGGCTTACAAGATCTCTGAAAGTTAAGC +TCTAGCATATCACTGAATTAATGAATAAATGAATGAATGTTGCAAAGAGCAGAGTAGCTC +ACCCACAGTAATTGGTTTCCTAGCAGGATAGGGGGTTGCCCTTTCTGCATAAACCCTTGT +GGTTTCAGCTCCAAACAGATCACATACATTGGTGTGAGGGTTCAGAGCACAGCTGTTATC +AGAGCTGCAAAAGGACAACGAAGAGTTAACTCTGTATCTGAGATACTAAATATCGCTACA +ACAATGTGGTGAGAAACACTGAGACCAGATACTGTCATTTCTTCATCTTTTTTCACTGCC +TCAGGTGTCGGCAAGGACACATATGATGCAGAAGCAAGGGCAGAATGACTTTGTTTTACC +CTTTAAAGGGAGAGGATGGCAGAGATTGGAGCAGGAAGGAGTGAAAAGAGGAAAGGGGAA +AAAGCCATTAATATTTTACATTAGGCTTAAAAATTCTCAGTTACAGCTTTGGCTAGGAGG +AAACATTTCCTTGAGAATGTTTGTTAGATGTTTTATGCTGCATGATCATACAAAGGACTG +ATTTATAATTAGTCCAGTTACTTACCTCTGTGTGTAATCGGGAATGGCATAGGCATTTTT +TTTTGACAACTATGTGCCACTCAGCGTTGCTGATTACATCTTATTTGACAGTTTTTAATT +ACAAAAGTATCAATTGATTTTTTTTTTAAATCAACAGTTCCGTAGTCCTGATTGATGTGA +AGCGACAATAGATCTGAATGAATTTGTAGAACTTGGTGGGACTGTATTTATCACATTGGG +TATGAGATTCCTGACATATGTTGCCTGGCTGCAGCACCAAGGCAGTAAGACAAGGGGTGA +TGCTTGGATGTCTTGTCTCAGTCATGGCCAGGGTGTAATGTGTCTGTCATTTAACTGACA +GGTCTATACCTTGGCCCCAGATGCTACAGCTCTTCACACTCTGCATAAGTAATATACCCC +CTATTATGCACATTCGCTCTGGGATTTTGAATGAATAAATTCTGAAATGCTCTCACTGAA +AGCTCCAGAATCCAGATTTTTTAAAGTGCACATGTAATTAATTTTGCTTTAGAATTTTGA +ATTAATGCCAAGAGAAATGCCTTGCTCTATCTCTTTATTAATTTCCAGGTATGAGCCTGA +AGAAAACAGCCAGCACTTTGCTTGAAATCATATGAATAATATTAGAGTAAGAATGTCTCT +GTTGGAGACAAAAACATTATATTTGGGTCTCTTGGTAATCTATCCATTGGTTAATGGACC +CAGAACCCTCTAGACAGTTCACAAATCCACATAACAGGGCAGAATTTTGCATTAGGTTTC +CTGACTTAGCTGAAAACTGTGACAAATCAGATGCAGCCAAAGAGTTCCCTATTGATTACA +AATGTAGGGATCAAGAGTAAGTTATTCCATCTAAGGCAGCATTTATTTAAATTTAAAATG +GTCCTTCCTGGTAATCTCAAATTGGATAATGGCATACAAATCAATGGAATTTTTCAGAGT +ATTAATTCCATCTCATTTGAGGGGCTTCCTATTCAATATTTGAAAGAATAGGTGTTGGTG +TACAGTCAAATTTTGGGGGACTGTAAGAGTTTGGGTGAATATAGGCCTAGCACCGTGGCT +CTCACCTGTAATCCCAGCACTTTGGGAGACCGAGGTGGGTGTATCCCTTGAGGCCAGGAG +TTCAAGACTAGCCTGGCCACGTGGCGAAACTCCTTCTCTACCAAAAATACAAAAATTAGC +TGGGAGTGGTAGTTCACGCCTGTAGTTCCACCTACTCCAAAGGCTGAGGCACAAGAATCT +CTTGAACCCAGGAGGCAGAGGTTGCAGTGAACCGAGATCAGGCCACTGCACTAAAACCTG +GGTGACAGAGACAGACCTTGTCTCAAAAAAAAAAAAAAAAGTTTGGGTGAATTTAGAAAA +GAAAATGAAGTTTTGGGACAAAATGTAAGTAACTCTTAGTTTTTTTTAAAGGAAAATAAA +CAACCAGTGGTCTTGAAAAAAAAAAGGCGGGGGAGGGGTGTCAAAATTGCAAGCCCTGTC +AAAGTACTGTTTGCTACACAAGTATCTTTCATAGTTTGCCAATATCATTGACTCAATTTC +TTTCTCTAGAATTTGAGCATAGCACTAGGTTCATATAGGTAGGTTATAAAATGTTTTAAT +ATTCTCTACCTTTAAAAAATATCCTAGCTGAATGTATAAACCATCAGTTGCCCATCATCC +TATCTGGTGTATAAATTCCCTATATATCACCCTGGACGACAAATAGTTCTAGCTAAACAC +ATCTAAAAACAGAAAGGCCTCAATGTCCTAAGACAACTGAAGCAAACAGCTATGGCCTAC +CAAGTCAAAAGTTAAAAAAAAAAAAAGGGGGGGGCCTTACTGGATCAGGTATTTGTGTAC +TAGTATTCACAGCAGCATTATTTGTAACAGCCAAAAGGTGGGAATAGCCCAAATATCCAT +TGACAGATGAATGGATAGACAAAATGTAGTATATACATACAATAGAATATTAGCCTTAAA +AAAGAATGAAATTTTGATACATGCTACAATATGGATGAATCTTGAAGATATTTTAAGTAA +AATAAGCCTATCACAAAATGGCAAATATTGTACAATTCCACTTATGTGAGCTCTCCAGAG +TAGTAAAATCCTAGAGACAGAAAGTAGAATGGTGGTTTCCAGGGACTGAGAGGAGGGAGG +AATGAAGAGTTATTGTTTAATGGGCACAGAGTTTCAGTTTGGGAAAATAACGTTTCGGAG +AAGGATTGTGGTAATGGTTGCAAAGCAATGTTAACTCACTTAATTCCACTGAATTGCACA +CTTGAAAGTGGTTAAGATGGTAAGTTTTATGTTGTGTTTATTTTACCACAATTAAAAACA +AAACAACAACAACAAAGAGCAAGATGTCTTAGAAGAAGCCAAGAGTTCTTGAGCATCTTT +TTGTACCATCATTTTTTTAAAAATTTTATTATTATTATACTTTAAGTTTTAGGGTACATG +TGCACAACGTGCAGGTTTGTTACATATGTATACATGTGCCATGTTGGTGTGCTGCACCCA +TTAACTCGTCATTTACATTAGGTATATCTCCTAATGCTATCCCTCTCCACTCCCCCCACC +CCATAACAGGCCCCGGTGTGTGATGTTCCCCTTCCTGTGTCCAAGTGTTCTCATTGTTCA +GTTCCCACCTATGAGTGAGAACATGCGGTGTTTGGCTTTTTGTCCTTGTGATAGTTTGCT +GAGAATGATGGTTTCCACCTTCATCCATGTCCCTACAAGGGACATGAACTCATCCCTTTT +TATGGCTGCATAGTATTCCATGGTGTATATGTGCCACATTTTCTTAATCCAGTCTATCGT +TGTTGGACATTGAGGTTGGTTCCAAGTCTTTGCTATTGTGAATAGTGCCGCTATAAACAT +ACATGTGCATGTGTCTTTATAGCAGCATGATTTATAATCCTTTGGGTATATACCCAGTAA +TGGGATGGCTGGGTCAAATGGTATTTCTAGTTCTAGATCCCTGAGGAGTCACCACACTGA +CTTCCACAATGGTTGAACTAGTTTACAGTCCCACCAACAGTGTAAAAGTGTTCCTATTTC +TCCGCATCCTCTCCAGCACCTGTTGTTTCCTGACTTTTTAATGATCGCCATTCTAACCGG +TGTGAGATGATATCTCATTGTGGTTTTGATTTGCATTTCTCTGATGGCCAGTGATGATGA +GCATTTTTTCATGTGTCTGTTGGCTGCATAAATGTCTTCTTTTGAGAAGTGTCTGTTCAT +ATCCTTTGCCCACTTTTTGATGGGGTTGTTTGTTTTTTTCTTGTAAATTTGTTTGAGTTC +ATTGTAGATTCTGGATATTAGCCCTTGGTCAGATGAGTAGGTTGCAAAAATTTTCTCCCA +TTCTGTAGGTTGCCTGTTCACTCTGATGGTAGTTTCTTTTGCTGTGCAGAAGCTCTTTAG +TTTAATTAGATCCCATTTGTCAATTGTGGCTTTTGTTGCCATTGCTTTTGGTGTTTTAGA +CATGAAGTCCTTGCCCATGCCTATGTCCTCAATGGTATTGCCTAGGTTTTCTTCTAGGGT +TTTTATGGTTTTAGGTCTAACATTTAAGTCTTTAATCCAGCTTGAATTAATTTTTGTATA +AGGTGTAAGGAAGGGATCCAGTTTCAGCTTTCTACATATGGCTAGCCAGTTTTCCCAGCA +CCATTTATTAAATAGGGAATCCTTTCCCCATTGCTTGTTTTTCTCAGGTTTGTCAAAGAT +CAGATAGTTGTAGATATGTGGCGTTATTTCTGAGGGCTCTGTTCTGTTCCATTGGTCTAT +ATCTCTGTTTTGGTACCAGTACCATGCTGTTTTGGTTACTGTAGCCTTGTAGTATAGTTT +GAAGTCAGGTAGCATGATGCCTCCAGCTTTGTTCTTTTGGCTTAGGATTGACTTGGCGAT +GCGGGCTCTATTTTGGTTCCATATGAACTTTAAAGTAGTTTTCTCCAATTCTGTGAAGAC +AGTCATTGGTAGCTTGATGGGGATGGCATTGAATCAATAAATTACCTTGGGCAGTATGGC +CATTTTCACAATATTGATTCTTCCAACCCATGAGCATGGAATGTTCTTCCATTTGTTTGT +ATCCTCTTTTATTTCATTGATCAGTGGTTTGTAGTTCTCCTTGAAGAGGTCCTTGACATC +CCTTGTAAGTTGGATTCCTAGGTATTTTAATTCTCTTTGAAGCAATTGTGAATGGGATTT +CACTCATGATTTGGCTCTCTGTTTGTCTGTTATTGGTGTATTTTTTGTACCATCTTACAC +TCTACTTGCTCTGTGCCCCTGTGTGTCTGACTTCTCCTTCGTGCTTTCGACCTTCTTTTT +ACACAACCATCCTGGATGGATAAGCCTGCCCAGCGTGTTTCCTAAGACATAAGTAGATGG +ATTTTGTTCAAAAGCCTTATCCCAAGGGTTGACATCAGTTCTAATGTGTCTCACTATGGT +TTCTCCCAGGAGTCTTCTCAAAACCTCTTGGCCCCACAATCTCAACTGTTAGCCCCAAAT +GCCAGTATCTGGAGATTCTTTGCCAGGTTAACCCCTACTTTCCCCTTTCAACTCACAGGG +GCCCTAGGGACACATGTATTTGCCTGAAATCTCTCTCTTTTCTTGTGTTTGCTAATTTTC +TGGCATATCTTTTGCCTATCTTGATTTTTTGTATTTCCAAAATGTGTACATAGTTTAAAA +TTTTAGGATACAAATGCCATTCCTGGGTAACTAAAATGGTCTTTGCTACAATTATTATTC +CATGTGTGAGTACCTTGTGCATGCTTGGACATTATCAGCAAAGCCATGGGATTTGATTCT +AATGTTTATTTTAATTCAGCTGGTTCACATTATATAATAAAATCTGACTAATTCTGAATA +ATGGAAGTTAAGACTACTGTGATTTCCTGAAAAATGAGAATCATTGACTAATTTTCAACA +TAATTAAATTGTTTTCCTTTCAAATTCCATGTGTATCATAAACAAAGTAAATAGAAACTA +ATAGGTAAAATGAGATCAGTTACAGAATGATTATGAATCAAAATATAATGGCCTAATGAA +ATAAATGCCCTTGAACATATACTAATTGTTCAATGGTTAGACTCAGAAATTAAAAGTACC +TTGATAGGTGCTCTCATTGTCTTCTCTCCTGGACAGTTGGATGATTTTCTCCCCAGGTAT +TCTTCTTACCTCTTTGAGAACCCCTTCCACAACTTCTTCACTCTTGTCACTTCTCAATAC +TCTCATATTTTTTGCTCACTGGTCTTCTTACTTCTCATAGTCTTCCGGATATAATTTCAA +GTTCTGCCTACTTGCTGCTGTTTCTCCAACTTCGGTCATTTTGTGTTCTCCAAGCCTGGA +TTCTCATCTGCCAACTGAACACTTCCACATCTCAGAATAAATTGAAACTCTAGATACTTT +GAACTGAATTCATGCTCTTTGTCCTCATAACTCATTATTCTGGTATTCTCTGTACTTCTC +TGGCCAGAAACCCCCTTTCTTAATCTTTTAGTAATAGCCAGAGTAGTGTCTAATATTGTG +GAACTCTTGCTATGTATTGGCCACTTTCATACGCAGCAGCCCTTGCAAGTGTACTTAATT +ATGTCCTCAGTTTATGGGTGAGCAGATGTAGATTGAGTGAAGTTAGGTGACTTGCCTAAG +AGGTCCAAGTGAAGGTTCAGGCATTAAGACTACAAGGTTTATATTTTTAATGCCACCGTC +TTAGTTCAAACCCTCATAATTTCACCTGGAATATCTATTAATTTGCCTTAAATTTCACCT +TACTCAGGTCCATTCTCTTTACTGCCACCAGACCTTCCTTTCTCCTTCCTTCCCTCAATT +CCTTCCTTCTTTTTTTCTTCCTTCCTTCTTCCTTTTGAGTGAGTAAAAAAGAAAAGACCT +ATAGTGTCTCTCTCCTCCTTAAATGTTTCAAAGTCTCCATCTTGCCATCCTAATCAAATC +CAGACTCCTTAACCCTTTATGATCAGGTCCCTGAATTCTTGCCCAGGATTTTATCTCACC +ATTTATCTAATGATTTCCTTCTCATCACTTCCAACTCTACCAAACTGCTTGAAATCATCA +ACAGACCATGCATTCTGGTCTTTGTACCTTTGCATGCACTTCCACCTTTGCCTAGAACTC +TCCTTGTACTGGCCAACTCTTAGCATTCTTCAGAACTCAGCCTGTCCTCCCTCTACCTCC +ACCATGTTCCTATATTGCTCTGGGCTCTGGGCTTTCCAAAGCTGTTTGGAACAATAACCA +AATGTTTTTGGATGGTTATATCAGATGGGTACCAGTGCAGGGAAGTCTCTGGTTTTAAAT +CACTTCCCTATGGCATTCACAGCATTCTTCTGCCTTTTTTCCTATTATTCCTTAGTTAAT +TACATCTTAAATCAATACGTCCTTACAGAAACAGAAATTCACATCAGTCTCCTCTTTTCT +CCTAAAATTTTTTCCAGTTATTTCAGCCACAGAGGTGAATACTTTGATTTATTCTTCTTT +CTTTCTCCCTTTCTCTCATATATTTTTATCTGAGAGGAAAGAGACAGCCCCAGTTACTGG +TCACATATGCAAACTGACATCTGTATCCAAGAAAAGAAAATGCAAAATGTTTAAAAGTGA +GATCAGCATAGTAAACCAATAGCATCCATCTGTAATGTGTTTAGAAATTTTTAGTAGACA +CTGTTAAGTCTTCACAATGTTTCCATTAACTTCTGATTTATCACAATGCAATTTGCTTTA +CATCCTACAGCTCCATTAAAAAGCAAATAAGAATATACTTCCTATTAGTTTTGTCTTGGT +TAATTATAGATATGGCAACATGCTTAGCTCCTACTATATTTTTAATTAAAAGTATCTATG +GCGATCAACTAGAATATGGATTACACAGATTTTATCGTTTGACCTGGAAACTAATAACCA +TTTGTAAGAGTATTTCTATAGGGAAAAAAAAGGCCTTCCAAGTTTTTAATAGCTGCCTTA +CAGACTTTGAGGCATAACCCTTCTAGAAGCTGTGGTCTTCTTACATTTAAATTTGTTAAA +GTTTCACTGCTTATTTAAAGAAAATTTAAATTGTTTTCCCTGCATGCTTAGGGAACAATG +AAAATGTAATGAAAAATGCATGCATTTTCAAGTGAGGCAGATTGGTGTTTAAATTCCACT +GCGACCATTTGTGTTTTCTATGTTAAGCTTCACTTAAGCTTTCTGAACCTCAGTTTCTTG +ATCTGTAAAATGAAGATTAAATCCACGTACATTCTGCATCTGCCCCATTAATAAATCATG +TCCACTTTATTCTCAAAAGGTATTCAGAATCGTACAATTTTTTTCACCTGCATGCTGCCA +TCCTGCTCCTAGTCATCATCACCATTATCTGGATTGCTGCAATGGATTTCTGTTTGGTTG +CCTTACTCCTGCCTTTGCCTCCCCTTCAGTCTATTTGCAACTTTGGCAGCCAGAGTATAA +ATATTAAAAAGTGAGTCAGTTACACCATTCCTTTGCTCAAAAGTCTGTAAGAGGTTCTCA +TTTCACATGGGTAAAAGCCAAAGTCCTCACTATGTCCCACAAGGCCCTACATAATTTGAT +TCCTATCCTTCACTATTTCTGACTTCCTAAACACACACACAGGCAGACACACACACACAC +ACATACACACACACCTGTGCCTTAGCAGTCTCCCTTGCCCACCTTTTTCCAGCCACATTG +TCCTCCTTGTTCTTAAATATTCCAAATATTTCAGGTATGTTCAGGCCCTTGCACTTGCTG +ATTCCTTTGCCTAGAATGCATTCTGGATATCCATATGACTTGCTCCCTTGTTTATATCAG +TTCTGACTCAAATATTTTCTTCTTGGTAAATCCTTTCCTAGACACGCTTTCTAAAATGGC +CAGTGACCCTCTTTCTCACCCTGTGCCCACACCTCATGTGCTCCTTTGCTTTATTTTCTC +CTTAGCATTTACCAGTCTCTAAACACTGTATCTTTTATTTACCCTCATTGATCTCCCCTC +CTAGAATGTAAGCCTCATGGAGGATGGGAATTTTTGTACTATTTGCTTTTGTTGTACTCC +CAGCACTTAGAACCCAGGGCCTGGCACATAGTAGTAGGCACTTGATAACTTTGGTTTAAT +GACTTCCTACCTCTCCAATTGTTTCAAAGATTAAGTAAAATAATCCATATAAAGGATCTC +CTACGTAGCAGTCACTGACTCTTAAGAAATTTGGCTTTGGTGGGAGTGGGGGCAGATGGA +CTTATGTTTAAACATACCTCTTTTGACTACCAGCTCTTGATCTGTGGGCAATTTACCTAG +GCTCTCTGAGCCTCAGCTCCCTCCCCACAAAACCCCTTCCATGTATGAAATGGGTTATAA +TTAACATCTCACCTTACTATATGGAATAAATAATATAATGTATATAAACTACTTGGCACA +GTGCCTGGCATATAATTAACACTCAGTAAGTCGTAACTGTTAATATGCTGATTTTTAAAC +ATCTTATCCCATGGAAGTTGAGGAAAGTAGATCGTGGGAAGTAGTGGGATGGACTCGGAG +TCCTTGGGTCCTGTCTTCTGTTTAATTCTGCTCTTTGATAGATGTGTGCCTTTGAAAAAA +TAACACAACCTTTCTCTGCTTCAACTTCCTGTGAGGAGTACAGTAAATGATGACAACATA +ACACCCAGGCAAGAACTGTTTGTCAAAGGGAAACTAGTTTCTCTATGGAAAAACTGTTAT +GAGTTTTATTAATAAACTAAGTATGTTGGGTAGAAAAGAAGAGTTCTACCTGCCAATATC +AATATGCATTTTAAATTTTAGATAAAATAAAGATAAAAATATTTTATTCTAATTATGGAT +GATCTGTGTCTTTCAGGACTGTATGTGCATTCTCCCAAATATCAGCTCTAATGTCATATT +TTTCTATAATAGTGTCAGACTAAGAGCCTATGAAAACCTTGTCATTCTCGGGCGGGTGTG +TGTGTGTGCGCACGTGCATGCATGTTGGGGTTAGGGTTACCAAATAAAATACAGGACAAC +CAGTTAAGTTTGAATTCATTGTAAACAATGAATATGGTTGTTATACAAGTTTTAGCGTAT +AAAAGTTTAGTGTAAAACTATTTATTGTTTATGTGAAACATTTTAACTGAGCATGCAGTA +CTTTTAGTTGCTTAATCTGACCAACCTACAGGGGGCGCTGTATATGTCTGTATGATACCC +TTAGGCTTGTGACACAGGAAATGCGGTCTGATTAGTTCTGCAGCCTTAGTTACAAGGGTC +AGCTGTGCTGAAACTAGGTAGGTCTCTGCTGGCTTACTGCCACTCCCAAATGCTGCCCTC +TACAACAGCCAATTACAGTGTCACCGAGCCTTCTCATTAGACACAATCTAATGAGAAATG +GCAAACGTCAATACTTTGGAATTTTGTTCTTTAGAAACTGTGTGGCAGATGAAGCAATTT +TTCAACATTTAGTTTCATAATGAAATGATATCTTTGAAGTTCTGCATATTATATAAGAAT +GGGTTGACAATATTTAGACCCATTGAGTGTTAGATATGGAAGGGTCTTCAGATGCCACCT +TGGCTACTCTTTTTATGCTGATAAGGCGACACTCAGAGAGTTCAACAGATTTGTGCAGGA +CTACATTCTGGCTTGGATGAGATTTTGGCCCTCTGTCTTCAGGCTCCACTGGTTTTCCCT +ACAGTGTTTCCCCTATGGTGCTCCCTATCTAATCCCTGCCATGACATTAGAATACACATT +CACGTAGTGACAGAGTAGGATCCATTTTTCTTTCTCTGTGTGGCACCTTGCCCAGGATCA +TTTGGATGTATGGATATAATTGATAATCTGGTGCACCATGGTGTGTAAACATTGCCATCC +ACCTGGCCACTGTTATTTTAAATCATAAGCTCATCTCTATTCACATAATTTTCTATGCAT +TAAATTGGGTCACTTAATGTGATTATACAAAAATAATGATCCTATTCCCAGGCCCTTATG +ATAATGCACATTTTTTTCCTATTCTTTGAGGTGCAATGTCAAAGGTAGATTCTAGTGTAA +CTTTCATCACTACAGCTTATTTAGATATTCTGCATTTTCAATATTTCAGTAAAATTTAAA +ATGTTCTTGCTTCAGAACAAATTCTAAATAATGTGACACCAACGGGACAATTGGAAATTT +AAACAGTGACTTTAACGGTGTTGGAAAAGAATGATGTTTCATTCTTTAGGTGTGATAATG +GTGTTGTAGTTACATTTAGAGACACATACTGATATACTTATGGATGTGCTCTTGGCTTGA +CTTCAAAATTATATTGTGGAAGGAGACAGGATTAAGTAGGGAATGGATCAAACAAGATTA +CTATTGAGATAATTACTGAAGGTGGATAGTGAGTACATGACAGTTTCATTATACTATGCT +GTCTACTTTTGTATATGCTTGAAATTTTCCAGAACAGTAAAAACTGTATCCTTATCTCCA +AACTCTAGTCTGCTTATACAAAGACAAAATAAAATTACATCACAGGAAATCAAAGATTTT +AATGCCCATCTTTAGTGGGGAGAAATAATATTTGTCCAAAAGTTCAGTACTTGTGTGTCT +GCTTCTTTTGTTCCCCTTCGTATTTTTGTGTTTTGGGGAGAGTAAACATGTAAGAGAAAG +AACTTAGAACTGGGGACTCAGGGAGTCTAGATTCTAGCAAGTTTCTGCCTTTTGTTAGTT +GTGTGACCTCAGGCAAGATACTTAATCTCTTTGGGTCTCAGTTTTCTCATTATGTAAAAT +GAGAACATTGCACTGTGTGGTTTCATAGGGCGTTTGGCTCTAAAATTGTTTGACTTGATA +TCACACGCAGGCTTTCCAAATCCCCTGCAAACTTGGCTCATGGAGTGTTTAGTCCTGTAT +TCTGTCTCTATTAATGGAGCAACGGGCTATATTCTGGGGACAACTGATTTTGACTTAAAG +ATATTAGGAATGAGACACCGAAATATTTTATGCTTCCCATGAATCTCCTGTGCAGCAATT +TATTATTTAGTTTCTTCTGAAATTGCTATTTTTTTTTTGAAATTTTCTAGTCAACAATGA +GTTACAGAAATTATTTCTCACTTTGAAAAGTTGAAATTTCTTGATATAGTGCTAAAATAA +ACTCAAGATTTTAAAAGTGCACCCTTCTTTTAGTAGGCCAAGGTCTTCTTAATAATACCA +TATATTCTATATATCATTTTATGATTTTATTACCTTCAGTTATCTCCCCAGTTTTCTTAA +TTCTTTTATGTATTCTCATGTAGCCAGATCTCTTCACCAATTTTATTACTTCTTTTTTTT +TTCTATTCCTAATTCTGGAATTTGGCACACATTACATATGTTGTATTTAGGCCATAAAAA +AAATGCTATAGTGAGACTTCTGAATATGTGAAGCACAACCTTAGCTCACTGTAGATCTAT +ATCTTTGTAACTTCTACACGAGTATTAAATTGTATTGCAGTCCTATAATCATTGCAAAAC +ATTTGCTTATTAAAAATATGTACTGGATACTACTTTATAGTAATACTAAGTATTATCTCA +ATGTCACATCAAAATTCATCCATTCAACAAATGTTTAATGAATGTCTTCTAGATGTGTTA +ATTCTGAAAAGCGATTTCACAGGAAAGAAGGCTTAGAAGAAATTACCAGAGGACACAGAT +TTCCAATTTTAAACTGATTTATTCATCAGAAAATGTTACTAAGTGACACTTACTTATTCA +TACACACAGTCCTCCTCTCGCGTAGATACTTCAAAATTACCATAATTAATTCAGAGACCC +AACTCTGGTCCTCTTAAAGTAAAGTGACTATTTCAGTGGAAGCTATAATGGAATATCCCT +AAGAAATCCATTGTCATCCTTAAAAAATACAAATCCTCTTGGCTTACTCAATGTCTTTGT +GATAATCCTTTTTATCAATCAGTAACCTTCTGGACCAGGATTTGTTTGTTTAGTTTCTAT +GAAGCAGTGATGCTTTTATCTAGAATCTTTCAGCACCAGTTTTTGATCTTCATGGAATCA +TGGGGTTTTCTCTCAATTTGTTAGAAGTACTAGACATGACAAGTACTATGATTTGTTCCT +TCTTTAGCCAGATATGTACTCTAGTGACAATGCCAGATTCTTGGATACTGCTTTTGTAAC +CATTCCTTTCTTTCACCATAATCTCTGACTGATACATTAGGGTGGGCTCTGTGGTTAGCT +ACTAATATTAACATTCATTCATTTAGTCATTCATAAACATTCTTTTGGTCATTCACTCTT +TGTTAGGTAAGTACAAGAGTGGCAAAGATAATCCTGGCACCCTCCATTTCAAAATAACAT +GTTTCTTGTTATATAACATTTCTTGTTAATAACAAAATAACATATTAGTGATACTTGGTA +GCATATCAACTAATCATATGGTCTGTGGTTGAACTTAAACAGTCTGTGTTCTCTTGATCA +CAGTGTCTTGAGTTTCTTTTTGAGTCTTTCATAATGTTTTCATGAAGATTCCCATCAGGC +TGCAGGGGAACATTAGGGAACATGTGTCCAGGGGAAAGGATTAACCAAATCATTCTCCCT +TCTTGGCCAACCCTTTGGAGATTTTCATTGTTGTTGTTTCACCGTCCTTTTAATACTCTT +TCATGAGGAATACTTCAAAGCCTTTTTAAAATGAAAAAAATTAGGGTCACTGGTTGCCCT +TTGATCATATAGTTCTCTCATTTTCACATAACTGCTTTATGTAAAAGAGGGCTTGATTTT +CTATTTGAAAAATCAATTTCCTCCCTGAGCCCCTCCTATTACTCTCCATAGTGACTTTTT +ATTCATTCATTCAACAAATATTTACCAAATGCTTATTGTGTGTTAGCACTGCATAGATAA +AAAACTCAGTAAGTATATTTTTCTTAGGAAAGCTATGACTCAGTTCTTTTCTCTGACCAG +CATTATTTTTGTTATTGATATCCCTCCCTTGAATTGTGTTTGCTTCTTATACTGAACATT +TACTGTGTTTGTTTCTGTTTGCCCTAGCATTCTAAGCAACACAACGCAATTTTGGGTACT +GTAAATTTTTTCAATTTTTTTAAAAATTAAAACTGAAGGAAATAATTCAAATATTCTTCA +AGCCATATCTATATTATCCTCAAAAACTTGTACCTTTATTTTTTTAACATTATCCTCTGA +ATGTATAGTATTAAACTATTCCCTAATTCTCACAGATAATGATGGAGTAAACTTTACTTC +TTGGGCAACTATCACTTTTAGGCATGGAGACCAGGGAACTTTGCCTTCCTTTTGTGTATT +TGTTCCCAGAATCATCTTCCTAAAGTCCCTGAATTTGTCTCCTGACCACATTTTAAATTG +TCCTCAATCTTCCAATCTGAATCTCGCCCTACTCTCGTGCCAACTTGTTAAATAGCCCTT +CAGTTCTCACTTGTAATCCTCATATAATTTTCCCTCATTGTGTTACAAGGATTTCTTCTT +CATTTCCCTTTTGTCTTATGAATTCCTGTGTTTGGGGAGTGGGTGGTCACTTCTGTGACA +AAGGAGAGAAAAGATTGCCAAAGATGTTATCTCTTGTGCCTTTTTTATTTCCTTTGCTCC +ACACTCTCCATTCTGTATTCTTGATCACATATTGTAGATGATTAGGTTGGGAGGAGAAAG +AAAATCAGGTGCATATTTCACATGTCAATTTGCCTAGAACGTATCAAACCTCTTAACTGG +TCTTCCAGGCTGTAATTTCTACCCTAGGCAGGCAATTCAGCAGACAGATAACATGTAACC +TGTTAAAATGCAATTGTAGTTATTCACACACAGATATTTCTTCAGGCACATTAAATAATG +CCTGTTCCCATTTCCTTAACATTCCCTTTATTTACAACTATCCTGATATTCAGTTCATTC +TTTAAGGAAGAACTCAAATGCTACTTACTCCATGAAATGATCCTTCACATTTGTAAGAGA +ATTAATTCCTCTCTCCTCTGTTCTATAGTTTTACTGGATTATTCTGTTATAATTATATAA +TGTTCCTCTTTATCCCTAATAGTTCTTTTGGCTTTAAATTTTATTTTGTCTTATATTAAT +ATTGCTATAGCTTTATTTTTTGTTTTATATTTTCTTTAGTATTTTACTAGAAGAGTTTTT +AAAAAACCTTTTTATTGTTTTGCCTTTTCATGTAATTTTGCTTTAGACATGTCTCATAAC +TGGACTTCAAAAAAAATCCAATCTGATAGAATTTAATCCATTTATATTTATTGTTATTCT +TGGCTGACTTGTACTTTTTCCTATTTTCAAATCTCAGTTTCAACCTTTACTAACTTTGTG +ATTTGGACTATTTGTTTAACTTATATATATCTTACTTTTGTCATCTGGAAAATGTTGGTT +ATAATAGTATCTACCTAATTGTAAAGAATCAGTCAGTTAATGTACGTAAAATACTTTAAA +TGGTGCATAGCATTTAGCTATGTGATAGCACTGTGTAATAGCACAGTGAATGCTATTACT +ACCACCACTGCCAGTACTACTACTACTATTTTACCTTGTTTTCTAAGACCTTATTTATTT +TATTTCTTTGTTTGCTTTTTATAATTTCCTGACTCACTGTAGAAAAACTTTTCTACTCTT +TTTTCCCTTTCTACTGGATTGAAACTATAAATTTTAGTCCACTGTTTTATTGGTTACAAT +TATTTTTGTTTATTTTTAAATTTACTTACAGTAGCATTCATCCATTTGGTGTACAATTCT +ATGAGTTGCAATGCATGCACAGATTCTTGTAACTATCACCACAATCAGAATTCTAAACAA +TTCCAAATGCACTATTTTCTCCTGCTGACCTCCGTAGTCAGACCTCCTACTACCCCTAAA +ATCTGGCAATCACTGATCTGTTTTCTGTCTCAAAAGTTTTCCCTTTTTCATCTAAATGTA +ATAATAGAGTATGTAATATTTTGAGATTGTGTTCTTTTACCTAGAAAAATGTCTTTGAGA +TGAATCTATATGGAGATCTATTACATTTTAATGATAAAAATTTTTACCAAAATTTAAAAT +TATTTAATATATCCACACTTTTTAAATGAAAAGATCTTAGCTATATGTACACACACTGAC +CCTCCATTCTTCTGTTTTTCTTCTTATTGTTGTCTAGAATTTTAATTCTACTTTTAAAAA +CATAATGTTTCTTTGTTTTTCAGGTAATTGAATGTAGCAAGAATGTTCTTTAATTCTTTC +AGTCACTCATTTTTTTTTCATCTTTTGACCCCTTTGTATTTACTATTTTTCTTACTGATG +CACATTCCTTAATAGTTTTTTCATCAAGGGTCTGTGAGTAGTAATTTCTCTTACTCTTTG +TCTGAAAATGTCTTTTTTTTTGCTGTTTCTTCAGTGTCAAATGATAGTATACCTTGAGAT +AGAATTCCAGATTGACAGTTTTCTTTCCATTTTCAGAAGATATTTTCTATTGTTTCCTAG +TCATATTGCTACTAATGAAAATTTATTGCCAATTTTGTCAATTTTATTTTTTGTAGATAA +GCAGTTATTCTTTCTGGGAAGTTTATATATATGAATATATAGTTATATGTATAGTTATTC +TTATAGAGTTATTCATATATATAGTTACTGTGTGTGTGTGTGTGTATATATATACACATA +TATATAGCTATTCTTCATTCAGTTTCACTAAATTCTACTGAAGTATTGTTTTATGTTTGG +TTTTTCAACTTGACCTTTGTTTTATACTTTTAATCTAAGAATATCTATTTTTATTCAGAC +TTGGAATTTTTTATCTATTCCCTTTACTCTATACTTTGAATTTTTTTAAGTATACTTGAG +AGTCTTAACTGGCATTTTATGTCTCTTAATTGCTTTTTTATGTATTTTAAAATATCTTTA +TCTTTTTGCATTGCATTTTAGGTGAATTTATCAATACTACATTTCAGTTCACTAATTCTT +ATCATTGACTCTTACTAGTTTAAAGTTTATTCCACTAACTTTATTTTAAAAAATTAAACC +TTTATTTGTAATATTCAAGATTTCTAATCTACTTACTCTTCTTAGCTATTTGTATTTCAT +AGTATATGGTTCTATTTTTTTTCCATATTATTGCTTCTCTGTATCTTTTTGAAAATCCTT +AAGGTTTTTATACTGAAGTTGTTACCAAGATGTTTCTGTTTTGTTTTGTTTTGTTTTTCC +CCCTCTGGAATACATTTATTTCCCACTTGTTGATTTCTTTGATTACAACTTTTAGCATTA +AATTTTCTTTACTGTTTTGGAGTTTTGGTTTGATATAGCAGATTAGTTGATGCTATTTCC +GTTGAGTCACGACTGTGAATCCCTGTCTCTTCTTTAATTTGATGGAATTTCTAACTATTT +TTTAACAACAGACAATGGTGGAACTGACACTGCATCAGTTTCTGGATACTTCTTATCTCT +TGTATCAGTCACTTTAGAGCCTTAAACTGAGACTTGAGAAGTTTCACTACCATGTGAATG +ACCACATGGAAAGACCCTGAGACTTCACAGAGAGGGAGTGGGGCCTAGCTGATCCCAACC +TTCCAGCCATCTCTGCCAGGGAACCAGGCATGTGAGCGAATCTGTCTCTGACCCTTCATA +TCACCCCAGCCACCATCTGAATACAATCAAGGATAATAATTGATACCAGGTGAAGCAGAA +GAATCACTCAGCTGAAACCTGTTGAAATTCCTGATCCACAAAATTATAAGATAGAATGAA +ATGGTAATTGTTTTAAGCCATTAAAGTTTTAGGGTGTTTTGTTACTTAGCAACAGACAAC +AGAAATGGGGTTTTATCTTGAATCTGACTGTTTCCCTGCCTCCTACCCGCACCCCTGCAA +TCTCTGTACATACCCTTCTTGACTACTGGTTTTGGGATGCTTCACTAAATTTCCCCATTC +CTCAGTCCAGAACTAAGGCTTAGAGCTCCTATTGAGAGCAGGTGATACGGGAGTTACTGC +AGATTGGAGTCACTGAGCTAAAAGCATCTTGGTCCAGTTCCTCACTTACATGAAGCACCT +CCACTATCATCCCTTCCCTCTGCCAGAGCCTCAGGAAATCTTTAGAGTGAGAACCTGGAA +GTAAAGCACATGAAAATGTGGAGCTCCACTAGGACTTTGACCCCAGAAGTGTCTCACTCT +CATTTAATTCACACTCAACCTCCAAAAATTCACACTCAACCTCCAAATTCAAGCTACTTC +GAAGTTTCAACCTCCAAAAATTCAATAATCCATTTTAAATGTTTCTATGAGTCTATGGCT +TCAGAGTTTATAGCTTCAGAGACTTCTGCTCCAGGTATGTAGATCTAGGCTGTGTCTCTT +GGATATGCCTGTCTCCCCAAATTTCAGGGTGATGGTTTGCTATACAGCCTCAGTTCTCTG +ATGGGTCCAAGAAAAGTCAGTGATTTTCAACTTATCCAGCGTTTCCTTGTAAGGATGACA +GTGATGACTTCCAAGTACCTTGCCTGTCCGAGCTCAAGCCAGAAATTAGTTATGGCTTTT +TTATTTTAAATTTTCATAATTTTTATAAGTATATATTATTGTTAAAAGTTTGGACCAGGA +TGCAGAACCTCCAAGTGTGAAATCACAATTCCGCCTCTACCACAAATCCTGAATATTTTC +TTTACAATTCTTTTTCAGTGTATAAAGCAGACTTTTTTTTTAAAAAAAACTATATAATCC +GTCTAACATACACGCAGAAATGTGCCCCATCCTAAGTATACAGAACAATGAATTTTCACA +AACTGAAAGTCACCAGTACAACTGGCACCCAGGTAAAGAATCAGAACATTACCACACTCC +CAGGAACACCTCTCATGCCCTCTTCAACTGCCCTTTCAACTTTACTAATTGCCCCCACTC +CCAAAAGACAACTACTATTTTGACTTCTTATAGCATATGCTAGTTTGGCTTGTTTTTGAA +CTTATACGTGGAATTGTACAGTATGTGCTCTTTCGTATCTGACTTGTTGGGTTTAATGTT +AGGTTTTAAAATTAATCTGCATTATTGTATATAGTTCATTCTCATTGCTCACTGTGACAA +TTTATCTGTCCATTCTAAAGTGTATGAAGATTTTCATAGTTTCCAGGGCTGCTGAAACTT +TCTAGTACATATTTTTGATGAATATATATGTGTGTTTCTATTAGGTGTATACCTTGGAGA +AGTCTAATTGCTGGGTCATAATGTATGCATACTTTCAGCTTTCGTGGACACTGAAAAAAA +AGTAATTTTCTGCATGGCTGTCCCTGTCCTCCTTCACTCCCTCATTTCCCTATCCCATCA +ACACTACCCAGAATGTATGAAATTTCTAGCTGCCCCATATCCTCATGAACATTTGATATT +TTGCGTCTTTTTCTCTTTTGCTGTTTCTAAAGTGTATAGTGGTGTTTCACTGTGGTTTTA +ATTTTATTTTCCCTATGGGTAATAATGTTGAGCATCTTTTTACGTTTACTGGCCCTTTGA +GCATGCCATCCATTATGATGGACTTTTAGTCAAGTCTATCTTTCTAGCTAGACTGGGAGG +TCTTTCTAGGCAGGGTTCTTATCATTACCTTTGCATCTCTCAAAATCTGCCATGATGTTC +TTCTCATGTGCCTTTCACCCAGTGTTACGGAGATGTCTGCTTAACTGAATGAACATATAA +AACATATAGGGTCCACTTTTATATCCCAAGCTGCACTTAGGAGCCACCACAAGGATTATT +CCTGAAAAATCAAATATGTAAGTTTTAGATTTTACAAATTTAAAAGATCTTAAGTAAATA +TTTATTCAGTGCCTAGTATATATTGGGTTTTGTGTGAAGCTGTGTTGGTGGAGGGCTTAT +GAGTGAATCAGAGACAATTCTTTTACTCATGGAGCATTTAGACCATGGGCCGGCCTAGAT +TAAGTGCTGGTTTTGAACGAGCCCGCCTTTAATATAAGACCTCGATGTATATTCCGCCAT +CTCGCTGGTGCAGTTGGATGGGAAGAAGCTGATGTATAGTACTTTAAGTATATGAACATG +GAAGCTACTTTGAAATTTCATCTTGTGAGATTTCTGCCTAGTAATTTTCTAAAAGGAAAA +AAAATTAAGATTTTTCACTGATACTTTTTTCAAAAGTGGTGTGAAGTGTGTTTCGGAGAT +GAAAACATCCAATTACTTGGTTCCTAATTTCTCAGCTATCCTAGACAGTCTCAAGTGTCA +CTGTGGGTTTTGTTAAAGAAATTCTCTTCCCAGTCTGACACAGCTTTGTTATCCTCTATA +ATAGCAGAGCTGTGACCTCCACCCTGAGGAAACACTCTTCCTGGCACTAACTATGACACC +TAGAGATTTCATTTTGCCTCAAACACTTTCCTATTTTCCTCCCATAACTGTGAAAAACTC +CTCTGTGGAATCAGGTACTTTATGCAGTAGGTACACACACTGAAAAAATGACTTTCAGAC +TGTGGACAGCCACCTCCCAAAGGAAAAATACTGTAGCTGTGAAGGTGATGGCACAAAGCC +AGTTTCTCCATGGTGCTTAGTGAGAGATCCCATTGTGTACTTATTTGCTTTTTTAAAGGT +ATCTTCATTCTGCTTTTCTCTTCTAATCAACTTCTGCTACAGAAAGTAAAGAGAAAAATG +AACCCTTCCATGGAGAAACTACATTATGTTTAGTACCTAAGGTATAAAGGGTGGCTGTTG +TTTTCTTGTTTTCATCATATTCAAAATGATTCAAAACTTTTCACCTATTGAAGATGAGGT +GACATATGTATCTCAACAGTTATGATGATTCACGTGCCCATTTCTTCACTCTGTGCTCTG +TGAAGTGATAAGAGATACTTTCGTAGCTCATGTTTCATGGAACTTGTGCCTGTAAACTAT +TTTAGGATTTCTGGCCTAATGCACTTTCCCTCAATGATAGTTAAAATTCCGTGGGAAGGT +TTCCACATGCCATGGACTTAAACATGTCCTAGCAGCCACAGCATGGCAGCTGAACTTTCT +TCTCCTTCCACCCTGTCTCTGGTTCCAGTGACTCGCTACCAGGGACTCGTACTCACAGAA +GAATGTTTTCTACAGGGAACCATTGTCCCTGTCCCCCTCCTCTTCATCATGATCGTGGAA +ACAGAGCTGATGCTGAAGTGCTCAAGGCGTCGAAGGCATGTGTGTTCCCTTGAGACACCA +GCACATTAAGTTCATATCTGATTCATGCAGAAATGGAGGGAGGGTGGGCATGGTGGCTCA +TGCCTGTAATCCCAGCACTTTGAGAGGCCAAGACGGGCTGATCACCAGAGGCTGGGAGTT +TGAGACCAGCCTGACCAACATGGAGAAACCCCCGTCTCTACTAAAAATACAAAATTAGCT +GGGTGTGGTGGCGCAGGCCTGTAATCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATCAC +TTGAACCTGGAAGGCGGAGGTTGCAGTGAGCCATGATCACACCACTGCACTCCAGCCTGG +GCAACAAGAGCCAAACATCATCTCAAAAAAAAAAAAAAGAAAGAAAGAAAGAAAGAAAAG +AAATGGAGGGAATACTTCTTTGCTTGCTTCTCTGTTAATCTTTTTCTTTATCAAATATGT +CCCCAAGCAACACACCTACGCCCCATGTCTCACTGAGTTTCTAATGAAGGAACTCTTTCG +TTTTCCATCTGTTGTCCCTGTCCCCAGAGGCCTGGCAGGGAGAAATATGCAAGTGACCAG +CACCACACTGCACTTAGAATCATCTCCCACTTCCAGTGACCAAGGCATTGTCCTTGGGTT +AGGCATGTATCCCCTACTCTCCCTTCCCTTAGCTGGAGTCCCTCCCAGAGGGTGCCTCAG +TTTCTCAGGAGAGTGGTCTTTTGTGGGGGCTTACCTTCCAGTTCAGCTGACTGAAATGTC +TACCTTCAACCACGCTCACAGCTTCCATATGCCTTTTTTCTGGGACTTCACCACCACTAC +TGCCCTCAAAGCCCTGACCACATGCCACAGTATTTATTTGTGAGATTACTTGTCTCGTTG +GTAAATACAGCTAGTTAGAAAACATCCTTAGTTATCCATTATCCAAACAAATACAGCTCA +AGTTTTGTATTTTGTGTTCATGAGCTTCTTTATGTGGTTTCTGAGATTCCAGATTCCTTT +GATACTTTTTCAAACCTTCTGCTTGCCTTTTTTTTCTGAGCTGCATTTTCTATTTCCTTA +CCTCGTTTAACTGCAAATACCCCATAGCATTTGAGTCCTTGCTTTTCTACTCTGTCCTGA +CCTCATCTGAAACCTCCTTACCTATTGCTTTGATTACCACAATGTGGTAATTACACTATG +TGGATCTCTTTTGATCAGTCACAGATTTGACTTTTTTTGGTCTATTCAAGTAATGTTTTT +CCAGACACCACTATGTGCCAAGAGCTGTAGTCATGATGAAGATGCCTCAAAATATACTCT +TAAGGAAGGCAGAAAAGGAAACAGATGATGAGATAGTGGCGACTTAAGACAGTCGTATGA +AAAAGGGGTGAAAGGAGCACCTATGGGAGATGACAGCCTTAACAGGTAAGGTAAGAGAAG +TCTTCTTGCATTGGCTACTGCTTATCCTTGGCTCAGCTCTCAGTTATTCATCACCTTCTC +TCAGTAATCAGTCCCTGACATGTGACCTTGATTGAGACAATAATTGCGCCTCATCCTCCC +TCCCACATTAATAGGTCCAGGGATAGACATATGACCTTAGTTGGGCCAATTGAAGGTATT +CCCCTAGAATTTTCCTAAGAATTCTCTATCCTCTTTCATATAGTGGCAGTTGCCTGCAAC +TGTGTTTGCAAAAAGCCTGTTTGTACAAGGAAGAAGTTAAGTTATTATATTGTGGGAGTA +GGGAAGGGAGGCAGGATCCACAAAGAGACCTGGCAACAGGTGTCCCTAGATCAGGCCATG +CCTGAAGTCAGGTCCATCACCGTTCTTTCTGTCAATACAGACTTCTTTTTTTTTTTTTTT +TCTGTTTAAGTTGCTCCAGGTTTTGTTTAAATTGGATGGTTCAGGATTTCGGTTCAGGAT +TGCAACTAAAAGAGATGCAATTTAAATGTTCTCTAAAGGAGGTGATGCCAGAGTTGAGTG +CTGAAGAAGGAGAGGAGCATCACAGAAAGGGGATGCACTTTGAGCAAAGGCTGCAATGAG +ATGGAAACGTGAACAGTGAGGACATTAACGGAGGGGGAGAGGACACTGCTCAAGGATATT +GGAGAATCATTTCCACTGGAGACCAAGCAGAGGAGTTTGGGGTTTTACCCTGAACACAAT +AATAAAATAATGAATTTTAGGAAGATAGCTTTGGTACCCCAAACTTTTTTACTCAAGTTC +ATTTGGAGAATGACTTGGAATGGAACAAAAACAAAGCAAGGAGAAAATTTAAACAACTCC +TCTGTTACTCCAGTCAACAATGATAAAGACTTGAATTAAGGCAGTGGTCCGGAGAACAGA +GTAAAATGGTGGCTTTAAAGGAGAATAAAGAGATGAAACTGCCAGGGCAGACCTTGGGCC +ACTCGAGGATGAAGGAGCCGTTCCACTGAGATGGGGGACATCAGAGGCAGAGAAGGTCTG +GAGGGAAGTTGAGGCATTTGCCCATTGTGCCTGGCAGCTCAGGCTATCCTCAAGCTATCC +AAGTCACCGCCAGATGAATTTTAATAAAATACTCTTTTCAATGTATTTCTTCATCTGTGA +AAAGATTGTTGAGGGAGGATAAGTTTAGATTAGTTGATCTTTAAGATTACTTCAGGTGAT +TAAAAAAATTGATTATGTGTCACTGCCAAGGAATCTACACAAAGATTCAAATTCTAATCT +CTCACCCTAGATTCTAAACCTTCCATTTTCATTTGGCCTCCCTGTGCCTCTTTAATCTTA +TTTACAGATGCTTTCCATGCCACACTCTCTTCTCTAGACAGAGCAGTTCCTTCCATGTTC +CTGCAGATGCCGAGTTTATAAGACGCTCCTGTACAGAATCCTGTTTTCCATTTCTTTCTT +AGCAATTGTCTTAGCTTGGCTAGTTCTCCATTCTATTGAGATGCCTTCCTTCTCCATACT +CTGCTCTGTCCTGGGGCCCTTATATGTCGTCTCTGAACGTGCACTGTACTCAACTCCTAT +GTAATACAATCAGTCATACATATTCTCTGTAATTTAGAACTCTAATTATTTCATATGTGT +TGGTTTGCTTTCTAAACCTAGTGCTTCTTAAGGGTCTTTGGTGTCTGGAACAGTGTTGGG +TGAATTGTAGAAGCATCATATAAGTCAGTTATACATGTTCTTCACGTCTCCTGGAATCTT +TCTCCACCTCTACTTTTTCACAAAATTCCATTCATACATCCTATAAGATGCAGTTCAAAG +TTTGTCTCATCTGTGAAGCTAAGCCCCAGACTGAAATGAATTATTTACTCTTATCTTCAT +ACATATGTAATATATAATATATATTTGAATATTTGTGCATATTTCAGTCATAATATTTTT +CAAATAATATAGAGCAGCATTTCCAATAATACCTATAAGAGGCAGATTTATTTTAATATC +CCTAAGCCACCACACCTAGTACAATGATTACTTGACCCTTTGAAATATTTTTGCAGGGAA +GAGGATTTCATATTTGTATCCATGAAGTCCCATTAGCACATTGCAGCATGAGGACAAGGT +TGAGCTCATCCAGGGAATAAGCCCATCAGCTGACAGAAAGCAGGTGATGAGATCTCTCAC +CAGATTAAAAAGGGAAGGGCAGCAACTCATTAGGAAACACAGAGATGTCTGCTTAATTAC +TTGAAAAATGTCTGAGCCAGTACATTTTATGACACCTGGAGGGTATAAACATGCCCATAA +ATTTAATTAATTTTCTTTGTTCTTTCATTGCACCTGTATGGCATAAAGGAAAGGAAGTCT +AATGAAAGTACAATCAAGCACTTCTGCCAGACTTCCACAGTTCATTTGGGCAATATTCAG +AAAATGAAATACTGAATTTCTTATCAGTTTATGGGGAGAAATGTATTTGGAAAAATGCAG +CCCAGCGGTGAAGTTATTCACATGTCAAACTCTGATCAATGGCTTCTTCAGCTTTATTTC +CAAAAAGAGCTTAAATCTCTTTATAGATGTATTAAAACATTTAATACTCATAAATCTCTA +AGGAGAAAATCAGAACTAGATATTTTTTTCTTGGGGGAAAGCATTATATGAGAACTAGAA +GGTGTAGGGGAGTTGGTCAGAACTATAGAGCAAGTAGCCCCATTTGCTCTCTGTTGTAGT +AGCATCGCCCACACTTTTGTTAAAAATCTTTAAATCTATGATATTGCTATTTTTATCAAA +TGAAAATGTAATAGTAATGAGTATGCTTGAATATCCATTGCAATATTACATCATTTAATG +AGTGCTCACTCTTTGCCAGAGACTGTACCAGTACTTTACATATCTGATCTTGAATCCTCA +TAACAGCACTGCAGATAGTAATAACCCATTTGAAATGACTCCCGGAAAGATTACAGGTCT +TATCCAAGGCAACATAGCTAGTAAGTTTTGAAAGTAGGACTCAAATCCAGGTCCTTTTGG +CTCCAAAATCTGTGCCCATTTAATTTTGTTATATGAACAGTAATGTCAAGCCATTTTTCT +CCTTGTTAATTCAGTGTCACTGAACATATGAAAAGTTTATAGACACTTCTTGTTTTCTTA +AAATAATTTTGACATCATTGAGCTTTGAGTAGTGAATTATTCATTGGAGCTTCTGGACAT +AGCCCGAACAATCTGCCCTCCCAAGAACTTACTGAAGAAAACTTCAACTGTGTATGACTT +CAATCCAAAATATACTTGTCTGCCTCCAGTTTTTCCTATAGATACCAGGAAGGGGTGTCT +TACTCAGTGTAGGAGAAAGGGAAGGAAACTATCGCGTATTGAGCTCCAACTTTGTGCTCA +GTATATATCCAGCCTTTTGCATGTATTAACTCACTTGATATGAGTTATGTGGGGAGAAAG +GTGACCATTCAGAAGCCTGTTACCAAGTAATTCTCACTGGGAACATCCCAGGGCAATGCT +GCCAATTCCCTTGGCATTCTACTTTTAGAAGAGTGGTGGTGAATGCTAAGATTTATAGTC +GAACATATCCTGAGGTGATTTGAAAACTGCTACTAGATAAAAGTGAAATGAAATATTTTC +ATTTTAGCTGTTAAATTTCTCATTTTGTCATGAAATACCATAGTTAATGCTGTTTTCAGT +TGTAATCTCTTGTAAACTCATTGACTGTTAATGTTTAGTGGGCCCATAAACTAATTTGAA +TTGATCTGATTTTGCACAATCAAGCCCGTTACACTTGTTTCAATTTTTTGCATCACAGCT +TTAACATCTGGAAGCTATGAAAAGCACAACAGCCTGTCTAAAGAGACTGTCACAAGAAAT +CGTGTTAAAGGACATATTATTAAGACCTGGCTAACCATTGGCACTAACGCTCCTGCCACG +CTCTCTCCGCTTCTGTATCCAGCATTACAGATGGGAGTAGACAAGAGGGGTGGAGCATGC +GTGGAAGGCTGCTCCGCAAGCCTTAGTTGGGAAATGCATTTCCCAAAACAGATTATTTTC +TAGGTACCTACTAAGCTCCCCAACCCATTCCCCCTCCCATTGCCCTCTCTGATTGGTTTA +TCCCAAGCAGTGATTAGTTCCTCAGTGATACTTTGGACTTAATCAGGGCTAGCTGACATA +TTCCTGGGGCAGAGTCAGAAATACTTTTGTATTCAAGATTCTGAACCATTATGTGTGTAT +CAGTATGGCTATATGTCTTTGTTCTTTCCTAATCATTATTCTTTGAAGAAGCTAATAAAC +AAATAAATCTGCCTTTGAAAGTGCAACATGTTAAAAAGAGTCCGCCTGTGATTATTTTCC +AGACGTAGCAAGGGAGAATTAAGGCACCAAATTCATTCACATTTTTGCATGCATTCTTAA +CCTTGATTTAGATTAATATATATTTGTGCCTTTTGCCGTTATATTTTATTGCTTTTTGCA +TTTTTATTGGTTTGTAGGTTTTAAAATATATTTTGGATACAATCCTTCATCAGACATATG +TATGAAAATATCTTCTCCTAATTTTTAGTTTTTCTTTTCACTCTCCCATTGATAGTTTTA +ATAAATATAAGTTCTTAATTTTAATGAAGTAAAATTTATCAATCTTTTATGATCGTTGCT +TTTTAAATTTTTAATGTATTTATTTTTTATTTCAAGATTTTTGGTAAACAGGTGATGTTT +GGTTACATGAATAAGTTCTTTAGTGGTGATTTGTGAGATTTGGTGCACCCATCATCTGAG +CAGTGAACCTGTACCCAATGTGTAATCTTTTATCCCTCACCCCTTCCCATACTTTCCCCC +GAGTCCCCAAAGTCCATTGTATCATTCTTATACCTTTGTGTCCTCATAGCTTAGCTCTCA +CTTACGATTGAGAAGATACGATGTTTGATTTTCCATTCCTGAGTTGCTTCACTTAGAATA +ATGGTCTCCAATTCCATCCAGGTTGCTGCAAATGTTATTGTTTCATTCCTTTTTATGGCT +GAGTAGTATTCCATGGTATGTATATAAGCCACATTTTCTTTATCCACTCATTGATTGATG +GGCATTTGGGCTGGTTGCATATTTTTGCAGATGCAAATTATGCCGCTATAAATATGCACG +TGCAAGTATCTTTTTCATGTAATGACTTCTTTTCCTCTGGGTGGATACCCAGGATATCTA +CCTTGATCCATTTGCTGGATGAAATGGTAGATCTGTTTTTAGTTCTTTAAGGAATCTTCA +CACTGTTTGTCATAGTGGTTGTACTAGTTTACATTCCCACCAGCAGCGTAAAAGTGTTTC +CTTTTCACCACATCCATGCCATCATTTTTTTTTTTTCAATTTTCTGATTATGGCCATTCT +TGCAGGAGTGAGGTGGTATCACATTGTGGTTTGATTTACATTTCTCTCATCATTAGTGAT +GTTGAGCATTGTTTCATATTTTTTTTGGCCATTTGTATATATTTTTTTGATAATTGTCTA +TTTTGTCCTTAGCCCACTTTTTGATGGGATTGTTTGTTTTTTCTTGATTTTTTGTTTGAG +TTCCTTGTAGATTCTGGATATTAGTCCTTTGTCTGATGTATAAATTGTGAAGATTTTCTC +CCACTCTGTGGGTTGTCTGTTTACTCTGATGATTATTTATTTTGCTGTGCAGAAGCTTTT +TAGTTTAACTAATTATCATCTATATATCTTTATTTTGGTGCATTAGCTTTTAGATTCTTG +GTCATGAAGTCATTGCCTGAGCCAATGTCGAGAAGTGTTTTTCCAAAGTTATCTTCTAGA +ATTTGTATGGTTTCAGGTCTTAGATTTATTTAAGTATTTGATCCATCTTGAGTTGATTTT +TATATAAGGTGAGAGATGAGGATCCAGTTTCATTTTTCTACATGTGGCTTGCCAATTATC +CCAGCACCTTTTGTTGAATAGGGTGTCCTTCCCCCACTTTGTTTTTGTTTGTCTTGTCAA +AGATCAGTTGACTGTAAGTGTTTGTCTTTATTTTTGGGTTCTCTATTCTGTTACATTGGT +CTATGTGCCTGTTTTTATACCAGTACCATGCTGTTTTGATGACTATGGCCTTATAGCATA +GTTTGAAGTCAGGTAATGTAATGCCTCCAGATTTGTTTTTTTTGCTTAGTCTCGCTTTGG +CCATGCAGGCTTTTGTTGTTGTTGTTGTTCCATATGAATTTTGAGATTTGTTTTCTAGTT +CTGTGAAGAATGATGGTGATATTTTGATGAGAATTGCAAGGAATTTTAGGATTGCTTTTG +GCAGTGTGGTCATTTTCACAATATTGATTGTACCCATCGATAAGCATGGAATATGTTTCT +ATTTGCTTGTGTCATCTATGATTTCTTTCAGCAGGGTTTTGTAGGTTTTTTTTTTGTAGA +GGTCTTTTTACCTCCTTGGTTAAGTATATTCCTAATAATTTAATTTTATTGTCTTGCAGC +TATTGTAAAAGGGATTGAGTTCTTGATTTGATTCTCAGCTTGGTTGCTGTTGGTGTATAG +CACGGCTACTGATTTGTGTACGTTAAATATTTATACTAAGACTTTGCTGAATTCATTTCC +CAGTTCTGGAAGCCTTTTGGATGAGTCTTTGGGGTTTTCAAGGTATACAATCATGTCATC +AGCAAACAGAGACAGTTTGACTTCCTCTTTACCCATTTGGATGCCCCTTATTTCTTTCTC +TTGTCCAGTTGCTCTGGCTAGGACTTCCAGTACTATGTTGAATAGAAGTGGTGAAAGTGG +GCATCCTTGTCTTATTCCAGTTCTCAGGGGGGATGTTTTCAACTTTTCCCCATTCAAGAT +ACTGTTGGCTATAGGTTTGTCATAGATGGCTTTTATTACCTTAAGGTATGTCCCTTGTAT +GCCAGTTTTGCTAAGGGTTTTAATCATAAGTGGATGCTGGATTTTGTCAAATGCTTTTTC +TGAGTCTATTGAGATGATCATGTGATTTTTGTTTTTAATTCTGTTTATCTGATATACCAC +ATTTATTGACCTGCAGATGTTAAACCATCCTTGCATCTCTGGAATGAGACCCACTTGATC +ATGATGGATTATCTTTTCAATATGCTTTTGGATTTGGTTAGCTAGTATTTTGTTAAGGAT +TTTTACATTTAGGTTCACCAGGGATATTGGTCTGTGGTTTTCTTATTTGGTTATGTCATT +TCCTCGTTTTGGTATTTGGGTGATACTGACTTCATAGAATGATTTAAGGAGGATTCCCTC +TTTTTTTTTTTTTTGGGAGTCTTCCTCTGTCGCCCAGCTGGAATGTAGTGGCATGATCTC +GGCTCACTGCAACCTCTACCTCCTGGGTTCAAGCAGTTCTCCTGCCTCAGCCTCCCAAGT +AGCTGGGACTACAGGCATGTACCACCACGACCAGCTTAATTTTTGTATTTTTAGTAGAGA +TGGGGTTTCACCATGTTGGCCAGGATGGTCTTGATCTCTTGACCTCATGATCCACCCTCC +TCGGCAACCCAAAGTGCTGGGATTACAGGCGTGAGCCACCACACCCAGCAGATTCCCTCT +TTCTCTATCTTTTGGAATAGTGCCAATAGGATTGGTACCAGTTTTTCTTTGAAAGTCCAA +TAGAATTCAGCAGTAAATCTGTCTGGTCCCAGACTTTTTTTGTTGGTAACTTTTTAATTA +CTATTTTAATCTGCTGCTTGTTATTGGTCTGTCCAGAGTTTCTATTTCTTCCTGGTTTAA +TCTAGGAGGGTTGTGTATTTCCAGGAATTTATCCATCTCCTCTAGGTTTTCTAGTTTATG +CATGTAACTGTGTTCACAGTAGCCTTGAATGACCTTCTGTATTTCTGTGGTATTGGTTGT +AATATCTTCCATTTCACTTCTAATTGAGCTTATTTGAATCTTCTCTCTTCTTTTCTTGGT +TAATCTCGCTAATGGTCTATTAATTTTATTTATCTTTTCAAAGAACCAGCTTTTTGTTTC +ATTCATCTTTTGGATTTTTTGTTTGTTTATTTGTTTCAATTTCATTTAGTTCTGCTCTGT +TCTTGGTATTTATTTTCTTTTGCTGGGTTTCGGTTTGGTTTGTTCCTGTTTCTCCAGCTC +CTTGAGGTGGGACCTTAGATTGTTTATTTGTGCTCTTTCAGCTTTTTGATGTAGGCATTT +AATGCTATGAACTTTCCTCTTAGCACTGACCTTGCTATATCCCAGAGGTTTTGATAGGTT +ATATCACTACTACTCATTTCAAAGAATCTTTTAGTTTCTATCTTGATTCCATTGTTGACC +TAACAATCATTCAGGAGCGGGTTATTTAATTTCCATTTATTTCATGGTTTTGAGGGTTCC +TTTGGAGTTGATTTCCAATTTTATTCCACTGTGGTCTGAGAGAGTACTTGCTATAATTTC +AATTTTCTAAAACTTGTTGAGATTTGTTTTGTGGCCTATCATTTGGTCTATCTTGGACAA +TGTTCCATGGCTGATAAATGGAATGTATATTCTCCAGTTGTTGGGCAGAATGTTTTGTAA +ATATCTGTTAAGCCCATTTGTTCTAGGGTATAGTTTAATTCAATTGTTTTGTTGTTGACT +TTCTGACTTGACCTGTCTAGTGCTGTCAGTGGAGCACTGAAGTCCCACACTATTATTGTG +TTGCTGTCTGTCTCAGCAACACAATAATAGGTCTTGTAGTAATTGTTTTATAAATTCGGG +ATCCCCACTGTTAGGTGCATATTTATTTAGGACTGTGATATTTTCCTGTTGGACTAGTTC +TTTTATCATTATGTAATGTTCCTGTTTGTCTTTTTTAACTACTGTTGCTTTAAAATTTGT +TTTGTTTGATATAAGAATAGCTACTCCTGGTGGATTTTGGTGTCCATTTGCATGGAATAT +CTTTTTCCATTCTTTTACCTTAAATTTACATGAGTCTTTATGTGTCAGGTGAGTCTCTTG +AAGACAGCAGATACTTGTTTGGTGAGTTCTTATCATTCTGCCATTCTGTATCTTTTAAAT +GGAGCATTTAGGCCATTTACATTCAACGTTAGTGTTGAGATGTGAGGTACTATTCTATTC +ATCATGCTATTTGTTGCCTGAAAACCTTGGTTTATTTTTCATTGCATAGTTGTTTTATAG +GTCCTGTGATATTTATGCTTTAAGGAGATTCTATTTTGGTGTATTTCACACATTCATTTC +AAGATTTAGAGCTCCTTTTAGAAGTTCTCATGGTGCTGGCTTGGTAGTGGCAAATTCTCT +CAGCATTTGTTTGTCTGTAAAAGACTATCTTTCCTTCATTTATGAGGCTTAGTTTTGCTG +AATACAAAATTCTTGGCTGATAGTTGTTTTGTTTAAGGAGGCTGAATATAGGACCCCAGT +CCCTTCTAGCTTGTAGGGTTTCTGCTGAGAAATCTGCTGTTAATCAGATTCTTTCCTTTG +TTGTGACTTTAGATAACCTGATGACTATGTGCCTAGGTGATGATCTTTTTGCAATGAATT +TCCCAGGTGTTCTTTGAGCTTCTTGTACTTGGATGTCTGGGTCTCTAGGAAGGCCAGAGA +AATTTTCCTCGATTATAGCTCCAAATATGTTTTTGGAAAAACTCTGACTTTTAGACTTAT +CTTCTTCCTCAGGAACACCAATTATTCCTAGGCTTGGTCATTTGACATAATCCCAAACTT +CTTGGAGTTTTTGTTCATTGTTTTTAAATTTTTTTTTTTTGTCTTTAATAGATCAGGTTA +ATTGAAAAGCCTTGTCTTTGAGCTCTGAAGTTTCTTCCTCTACTTGTTCAATTCTATTGC +TGAGACTTTTCAGGGCATTTTGCAATTCTCTAAGCATGTCCTTTATTTCCAGAAGTTGTG +ATTGTTTTATATTTATCCTCTCTATCTCACTGGAGATGTTTCTATTAGTATCCTGTACTA +TGTTTTTGATTTCTTTGAGTTGGACTTCATCCTTCTCTGGTGCCTCTTCAATTGGCTTAA +TAGTCAACATTCTGAATTCTTTTTCTGGCAATTCAGAGATTTCGTCGTGATTTGGATCCA +TTACTGGTAAACTAGTGTGATCTTTTGTGGGTGTTAAAGAATCTTGTTTTGTCATGTTAC +TGGAATTGTTTTTGGTCCTTCTCACTTGGGTAGATGTCAAAGGGAAGATATAGGACTTAA +GGGCTGCTGTTGAGATTCTTCTGTCTCATGGGATGCTCTGTTAATGTGGTGCTCTCCCCT +TTCCCCTAGGGATGGGGCTTCCTGAGAGCTGAACTAACTGTAGTGATTTAGCCACCCAGT +GGAGCTACCCAGCTCTGGGCTGGTACCAGGGAATATCTGCAAAGGTCCTGTGATGTGATC +TATCTTCAGGTCTCTCAGCCATGGATACCAGCACCTACTTGGTGGAGGTAGCAGGGGAGT +GAAGTGGACTCTGTGAGGGTCCTTGGTAGCATTTTTGTTAAGTGCACTGGTTTTGTGTTG +GTTAGCCTCCAACCAGGAGGTGGCACTTTTAAGAGCACATTAGTTGCAGTAGTATAGGGA +GGATCAGGCAGTGGGTGGGGCCATAGAGCTCCCAAGAGGCTATGTCCTTTGTCTTTGGCT +ACCAGGGTGAGTAGAGACAGACCATCAGGTGTTAGGCATATCTGATTTCTGACTCTCCAT +GGACAAGGCTTGCTGCCCAAGGAGTGTGGTTTCCAGGCCAATGGAGTTATGTTCCCAGGG +GGATTATGGATGCCTCTACTGTGTCACACAGGTTGCCAGGGAAGAGGAGGAAGGCCAGCA +GCCACAGGCCTCACCCAGATCCCATGCAGCCCTCCTCACCCTCCGCCAACAGCACTGAGT +TTATTTCCAGGCAGCTGGTGGTCAGAGCTGAGAATTTGCCCCAGGCACAGTTCCTTGGCT +CTCCCATGGAGCCTGCAGTGGCAATCCACCACCTTCAAAGGGTCTGTGGATTCTCTCAGC +TTTCCTGGTATGTTCTTGTGGTAGTTCTTGGAGCACAAGTTCATGATGTGGGTTTCCACA +TGCTTCTCTGTCTGTTCAAGTGGGAGCTGCAAGTTAGTCTTGCCTTCTATCCACCATTTT +CCTACCTCTTTCACCATTTTAAATATATCCTCTACATACAGTATCAGCTTTTGCACATAT +GCATGGCATAGAGGTTAAGAGAATGATCTCTGAAGTCTGACTACCTGCCAGATCCTAACT +CCACTACTTAGTAGTTGTGTGAATGGGGCAAAGTTTTTAACCTCTGTCAGCCTCAGTTTC +CTTATTTGTCAGGACTGTGTCTCATAGGATTGTTGTGAACATTAACTGATTTAAAGGAAT +TAGAACAGTGTTTGACATAAGATAAATGCCTAATGGATCTTTATCATTAAGACTCTATGC +ATTTCCTAGTTATTTTAATAACAGTCTTATTCACAATCAGGCACTATACCCTTCCTGTGG +AAAAGGGAAAAATACAGAAAATGAGTAAAAATGACATGTATTTCCCTTATCCCACCACTA +AGAGGCAATTTATGTTACCATTTTGATGTGTTTCATTCCAATCATTTTTTTTTTACTTAA +TTAAACTTTTCCACTTATTATCAATGGATATTATTATCAATGTAACCTTGAGCAAATCAT +TTACCTCCTCTAAGCCTGGCAAACTTTGTATGTAAAATAAAGGTAATTTAGTACCTACAT +TATAGGGCTATTGTGTGGATTAATTGAGTTATACCATGTAAATTACTTAGCTGGGTACTT +GGCCTATTTTTAGGTTAAACAACATGAAATTGCCAATATTCACCTTTTTTTTTTACTATG +AAAAAGGCAATTTCATACAGTCCATCCTAATGAGAATATCTCAATATACTTATTAGCTTT +TTTGATAAGGCTTTGCAGGGTGTGATGGTACACAGCAAATTGCCCTTGGGCTTCAGCCCA +CAAGGAGACCACACTCCTACAGGCAAGGAAACATTTGTTTAAAAAGAAACAAGCAAACAC +CTGCAAGGCAAAGCTGATCATGGCCTAACAAAGACAGGTTAAGTGTTGGAAGATTCCAAG +CAAGGTAGACTACCTCCATCTGCAAGGATTCAGGGTGGCTCTATGATAAAGTTGACATCT +GAGCCTGACTCAGAGCCTGAAGTCAAACTTTCCTGACATTTCCTACCAAAATGTCAGGAA +AGGCTTTCTAGGTAGAGGGAACATTCAAAGCAAAGAAAGAGCAGTAGGAATGTACAGTGT +ATAATTTCTTTGGTTAGAACATAGGGTACATGAGAGCTGGAGGTGGAAGGCAAAGCCTGT +GTATTTTAACACTCAGCACAGTACTTGGGCCGTGGCTGGCACCTGGTATGTGCTTGAACC +AGTGCATACTAAGGGATGTGAGCTCTGTTCAGTAAAAAAGAGAGTGGGACATTTTTGACC +AAAGGAGTACAATTGTCAGTGCCATCCTTTGGAAAGTTGAGTTGGGGAATATATGTATCC +TTGAAAACTTGAAGTGAAGCTCCTAGAGGCAGAGACACTTCTGTTTGTCCAGGGTCCTGC +TAAGCTATCCAGCCTCATTTCCAACCTTTCCTTCCCTCCTTTTCCCCTACCTCCATCACA +ACTAATGTCTAACTCTGCTTAATTTATTTTAGTTCCTTCAACTTGCTGATCAAACCCTCT +TGTGTCTCAAACCTTCATACGTGTTGTTGTGTCTGCTTTGAATCTCCTTCTCTTCACCAC +TTGGCCAACTCCTGCTCATCTTCCATCTCGGTGGATACATCATTTCTTGTAGAAGGCTTT +CTCTGACTCACTCTAGCCGGCAAATCTGGATAGCTTCTCTTCTGGGGACTCCCATAGCAC +CCTGTACTTCCCACATGTTATCTGTCTCTCTGTACTTGCCGCCTAACTACTGCAGACTGA +AAGTTCTAAAAGGGTGAAGACTATATAACCTATTGGCTAAAAGTGGGGATTGAGAGATAT +GTATAAACCTAGTTCTATATCCCGATTCTGCAATTCAGTACTAGAATGACTTTGGATGAG +TTACTTGATGTAGCTAACATTCATGTCTTATCTGTACAATGGAAATAATAACAGAGACTA +ACTTTAGGGTTGGTGTGAGGAATGAAATGTGGTAGCATAGGCAAAGTTTAGCAGAGTGCC +TGTAATATAATTAAGACATCATAAGTACTTATTAAAATTTTGCTGCTAGTAGTCACAATT +GGACCCCTTGGAGTGCTCCACAGCAGCACACTACTGGGAGCATACTAGGTGTGCCAAATA +TTGTTGGATGATTGAAACAATGCCCGTGGAAATGATGAAGATGTAGATGTGAAAAATGTT +TTAGAGGTAAGAGCCAATAGAACTTAGCAGTTTACCTAATTATAGGAGGAGACAAGGTAG +TGGGCAGTCTTTAACTCAGGCCTGAGCCTAGAGAAAGGGAAGACCAGTGCTGCTTTTTTT +TTTTTTTTTTTTTTTGGAGCAGAAGTGGTGGGTGAGACAACATCATCAATTCAGAACTCA +TTTAGGGAGCATACTGAGTTATATGTTTAGTAGCAAGCTCAACCAACATTTGGTCCTGGA +GCTGGGGAAAGAAATTATAGATGGGAGAAAGGCATGAATTTCATTTTAAGAAGGGGGACT +TTTTTGAGCCAATGCTTCTCTAACTTTAGTGTGCTTTGGAATAACCTGAGGAGGGTTTTA +AGGGGCATGCTTCTGGGTTTTATCTCTATAGATTCTGATCAATAAGGTAGGTCTGTGGTG +GAATATGCATTTTGACAAATAGCTTAGATGATTTCACTGTGACTTTGAACAAACTATTTA +TTATGAGTTTCAGTTTCTACCCTTATTAAATGAGAATGGTATCTACCTTTTGTAGGGTGA +AAAGGAGGCGAGAACACGCAGGGGTGTGTGTGTGTCTGTGTGTGCGCATGTGTGTGAAGG +TTATATAAGGAAAGGAAGTAAAGAGTTTCTGGAAGAAAACATGGTATCCCATGTGGTATG +ACAAGTCAGTAAAGGAAGGAGCGAGTGAGAAATGAAAGAAGGTTAGTGAGTTTGACATGC +AGAAGCCACAGATGAGAAAATTGTGTTCTTGGACAGAATACTAGGGCAGGAAGAGGTTAG +GAAGAGGGCAATGGGTGTTCCTTACTAATAGAATATTTAATGACACAGAAAAACATTAAT +GACATGTTTTTAAGTAAAATATAGTATAAATCAGAATGACACTATGTTTTGTTATAGCTA +AGTAGTTATATTATGGGCAGTTTTTATTTTCTCCTTTTCATCAATGGTATTTATTAATTT +TTCTACAGTTAAAGTATTGGTTTCATAACAAAAAATAAACAGTCTTGAATTTTCTGAGTG +GAGCTGAAAGAAAAAAGGTATCTCTAGGGATTACAGGACGGAGAGAAAGGCCTTTTCTTT +TAAGGTCAGAAAACATTTTTGCTTGCTCTTTAGAGAAGGTAGAGGTGTTGTCAGGTGAGG +ATGAAATCCTGGAAGAACCAATCTGGAATTGTGTCAGATTGAAGGGTTATCCTTAGAATG +GAGAAGGGAGACATTTTATGAAGAATTTCAGAGACAACTGATGAAAATATTAATGACAAT +ACAAGAGCTAAAAGTACTGTCCTTTACATGGGAATTTTCAAAATGCTAGTTCAATTGTTT +TAAGATATTTTAATTAGAGCACGAAGTCACAGATTTGATCCCCTAATGGACCAGTTAACT +TCTTCTCATTCCTAAAGGCTAAATAACTTAAGCTAACATCAGACACCTGTTTTGTAGAAA +GATGTCAAGGGTCACCAAAACAAAAACACCATGCAAGAGAGGATGAATGGATCATTGCCA +ATTTATTGGTATCATGCAAGGAAAAGCACATATGTATTCATTACTAAGGTGCTCCAGTAT +GACTTAGAACCTAACCTTACCTGAAGATCTGATTGAGGATGTAAAACCCTAAATCAAAGC +TCACGTTGTAAAGTTTTCTTTCCTTGAAATGAACTGCCCGAAAATGTTTGCCCATAGAGA +TCTAAGAAACACATTTTCAGGAAAATTGGTGCTTATCTGGACACTCGAGGGCATTGGTCA +CTGATTTCTAAGGCTGATGATTTATGATATCGTCTTTCATGTAATGAGTTTCAGTTTTCC +TGGATATTCAGACTGTTTCACCCTCTCTAAACCTTCCCCACTCAGGGAACTCATCAAGAG +GATCATGGATCACAGTCATCTGAGAAGAAGCTATTTGAGTAGCTTCTTTTGTGGTCAGAC +ATTTGTTGGTCCCTAGAGCGTTTACTAAATGGGACTCGATTCCATTTACCTGCCTGGAAT +GCTGCAGTTTTAAGTACTCCCTACTGGATTCCTGTCTGTAATGTCTTCTGAAATGTTGCC +TGGTAGTATAACAGAAGCTGCAGGGTTGCAGTGCATTCATTTAATTATGCAGGAATAATG +AGAAATTAAATAGCATTCTGATTCACAACTGAGGCTGAATCTGTAGCTGTTAGAAATATG +GATATTGGTGTCAGACAGAATCTGGTCTGAGACCCCCCTCTGCAAATCATTAGCTCTAAA +TCTCTAAGGCTCAGTTTCTCAACTGTTGTATAAAAGTCACTTCCTTTATAAGGTTATAGT +GAGTAGTGAATAAGATAATGCATGTTTATTAATTGTATAGTACCTAGCATATGTTAATAG +TAAATGCTTACTAAATATTAGTGGTTACTACTTCTCCTGTTACTGTTACTTGTCCATATA +CCCAGAGAGTATCTCCAGAAACATAAAACAAGTGTGTTCCAAGGAAAGATATTAATTTGC +CACATAGCCAGAACATAAGATTTATATAGGAATGAAATTAGAAGAATTAGCAATTTTCCT +TTCACAGTTAAGGACTTTGGATAAGAACATGATTTTGGATAGGTGCTCTCTGGGGGCAGT +TTTGGGATTAGCAGACATCAAAATCCAAGACATTATATCCATCTCCTAGGTCAAGGCAGT +TGAGAAGCACCTGTTGATGGGACAAAGGAAAATAAAGTGTGAATTCAAAAAAAAAAATCT +TGCTTATCTTCAATGCTAGATTTTGTGTGAAAATATGTAAATAGGTCTGTGCAAGTTTTG +TGTATAGTTCAGACAACATGGATTGGGGGTTCAGACATTGCTTTGGATTTAGACAGATCT +GTGTTTGAGTGCCTGATGAATCACTTTACTATCTGTGAGCTCCTGAGCAAGATACATAAC +CTCTATAAACCATATCCTCCTCCCTCTGTGGAAACTAATATAGATGCTGAACACCTGTTA +GCAGAGAGCATGGCATGAGATAAATAATCAGTACATGTTAGTTATATTTTTCTATGTGCG +AATGTGGCGTCAATATGTATTCAGGCAGACAACAACATTTTATCCCTAGGAAGTTCTCAT +GTGTGTCCAGATAAAATCAAGAATTTGTTTTTCAAGCCTGTTACTGTATTGATATAGAAA +TGAATAACCCAGAGATTCTTTTTTCATAGAACCCTTTCCGGGCAATTAACATATGAATTG +CTCAGATAGCCACTGGGGACAATCACACAGCCTAAGGAAGTACAGGGGGAAGGGCTATGG +AGGCACAGGTTCTATGTGCCCAGTACTGTTCCAAGCACCTGCCAAGTAATCTCTTTTGCA +AACCTCACATTAATGCTATGAGATAGGCAAATCTCATCTGTATTTATAGACAAATAAAAT +AAGACTCAAAAAGATTAAGTATCTTGCCCAAAGTTATATAGCTTGTGAGAGAAGGCAGGA +CTTAAACCCTGGCCTGTTGTCTTTAAAGGCACTTTTAAGCTAGTGTCAATTGTGTAGCAA +AAACAAATGTAATATTGTTATGACTATATTGTGGAACAACAACAGAACCCCCATGATGTC +CCGGTGTACTCTTGTGAGTCTTAGTTTGACTGAATTGATCCCAGATGTTAAACGCTAAAT +GCAATGCACTATTTTAGGTTTTTTTCTTCCTCCCTGCTATTCAGATGCAACCATTAACAC +AGTCAGGAAGTAAAATGTTACATCTGAGATAAATGCCATGTTCATGTTCCTTTTTTCCCT +CTCTCATTGTGTAAGATAAGAATTTTGTTATTATGCGACAATAGTTTTATTAGGAATAAA +ACACATGTAGGTTCATATGCCTCCAGGGCAATCGCATGCAGACAAGGAGCTCAGCACCCA +GCAGGCATGCATATGGGAGTTTCTTACCCAACTATGTTTCTACTAACCTTACTTTCCTTA +GCACCTACAGTGGTTTCCCCAGGCCACATCAGCCCAGGGGTGAAATTCAGTGGTGGAATA +CCATTAACAAACAATATCTCTTTGACTGTCTATACTTTCATTATTGTGTGACCCCATCCC +TACAGAAGGATTCCCTCAGTTATTACACAGAGAGTTGCTCATGTACAGAGTCTCACCAGA +TACCAAAGACTATCAGCTGGTTTCTTCCTCGCATGTTCTGACTTCCTGAAATGATGGTGC +TGTGCAGGCTTGTGTGAAGTAACTGGCTCAGTCTCCAAAATATGCTGTTTTGGGGCCTCC +AAAACAGCATTTGGAATCTTAAGGATACTGCTTGGTGCAGCAACTGAGCAGCACCAAGGG +CTTGCTGTGTTCTCTGGAATTCCTGAATCCACATCTACTTCTGTATGCTTCAGTAATGGG +CGAATACCCAGCTCTCCCATTTGAGTGCTTTACTCTATAAACCATAGTGGATCGGAGTAG +GGGTGGAGAATCATACTCCCTCCTCCTGGGGTCTGAGTTTCAGCTCTTCTGTCTGGTGGC +AGTGTGACTATGGGCAATTATTTAATCTCTGTTTGCCTACGTTTCCTCATCTGTAAAGTG +GGGTTAACAATAAGAGTACTTACCTCACAGGGTTGTACCTAGTCCAGAGTGAGGGCTCAG +CAAATGTTGGCCACTGTTAATATTGTATGAGTCCTCAAATCTAACTGGCTCTGGCACCCA +GGATACAGTGCAGAGATTTTTATCTTTTCCTCTTTCACTTTATACTTGCAGCTCCTCTCC +CTAGGACTCAACCTTGAGCTGGAGGATGCTGTGAGTAGTAAGCACTTGGGTTTATTCAGG +AATGCCCTGCTTTCCAACTCTGTGGCACTAACCTTCATTACATTTGTGTGCCTTTATTAT +TCCTTCCTTAGGTTTGACTAGCTGGCTCCTCGGTTGGTCCCTTGAGCAAATCAATTCTGT +TGGTACTAGGTTCGCAGGCATCCAAATGGGCTAAGATATGTCTGATGTTTGAATCCTAGC +TGAATTTCCTTTTGGCTCAAGCTGGAAACAAGGATTCATATTCTCAATCTGTCTCTCTCG +CTCTCTCTCTCTCTCTCTCTCTCACACACACACATACACACACACACACACAGATAGACA +GACACATGGAGTTATATTTTTTCAGCCCTGAAACCTTCCATTACCATTTGGTTATATACT +TGACTTCTTAGATATACTTGAATTCTTGTTAAATCTCATTCAAAGATACTTTTTCACTGA +AATTTCAACAGAACGTCATTGTGAAATGATGTTTTATATGAAACCTCCCAAGTAATCTTT +CAGTGATACTAATTAGTTCTTCAGTTACCTGAAACCAGAATTAAAGAATTGTTCACTAAT +GAAAACATTCACTTTAGCAGTTTGTTCAAGAATACCTATTTGTATGACTTCTAGATAATA +AATTATCTATTCTTCTTTTGTTCTTATTCAAGTACTATGTAAGTATCAGGTAATCCACAT +CTGCTATTCTTGCATCAACTTTAAAACATTTAATTCTTTTTTCCTCGTTGAGATTTGAAT +CACAAGGATTCTTTTCTAAAGGCAAAGTTGAAACAATGCTTCCAAGACAAAAATAGCATT +ATCCCTTATGCCAGTAATATTTGAACTTAGGTATTCATCTACTCTCACTTTCCTGCTCTT +TCTTAGTATTAATACACTATTCAGTGTTTGCTTGTTACATGCCAGGACATTTTACATCCA +TGAGGTCAGACTCAACTGTTATTTTGTGAACTATGAAGTGTATATATATAATAGTTTTTC +ATTCAACACATCAGCAAAGATTCCAATTTAGGTTTTAGTAAACTACTTGCATGTTTACAG +AAAAGTCAAATGCTCACTCCTGTTAAAGTATGGCAATCATTTCCATGTTAAAGTTTATTC +CAGAGTCTTGAAGTCAGCACATTTCCAAGTAGCTGAAAAACAACTGCAATAATAATAATA +ATTAATATTGACTGTATGACTACTACATGCCACCCTATGGGTGAGATAGTTTACAATAAC +TTTACAATAAATTCATTGTGCAGGTCCTGTTATTATTCCAGTTGTATAAATAAGGAAAAT +GAGGTTCAGGGAAGTTGAATATGCCACTGATATGGATTCAGATTCATACAATAATAGTGT +TTCCTAATTCTGATGAGGCTGTAAGAAAGACCTGAGTCACCAAAACCATCCCCACCAGCC +AATGGGGAGTCTCAGCTGGCATAACATATGAACCAGGTAAGTGAACATAAATGGCAAGAC +AAGCCATGTGCTGTGGTCAGCCTTCCAGGGCTGGCAGCATTGCTCCCCGCAGTGCATTTC +TATTGAACTAATCATGGTTAATGTCATCAGAATAACTTCTCAGTGAAGCAAGAATCTCCT +CACCAGCAGGAAACTGATAAAGATGGCTTGAGGATGCATGAAACATAGCCTTGGACTGGC +TTCATGCTAGATGCCTTTCAAAGATGTGTAGCTGCATGCGTAACCTAGCAAGTTGCTAGA +CTGATTGGAACTGCTCATATTGAGCAAAGGGCTGGCTGCAAGTCTAGGAAAGTGGAAATG +TCATAAATGAAGAAGGGCTCTTCGGATGGCAGCCCCACTTAATAACTGATTGCAGGGCAA +TCAATCTTTGCTCAATATGTACATGTCCCTCAGTTGATCCAGCATTGGCCTTCTCAGCCT +CATCTGTATACACTTGATGTCATTTTCTCATCAAGTATGCCGTCTCTAAAAATAAAAGAC +AGCAAGCATTACTAAAGCTGGAATGATTGCTTCTAGGCCTTTTGGCTAAGATCAAGTGCA +AAAGCTGGAATGAGAATATTCCTTTGCTGCCCTCTCAGGCTCTTAATCCTGTCTTTCCAG +AGCAGCTTATTTATACTACAGAATTTGTGATGTGTTTAATATATTTCAAAGTTTTTTCAT +TTGTTTTTAAATGAGAATTTATGGAAAGGGTTCTGCTCTGAAAAGAGAAGCAATTGGAAA +AATGCTTAGAGATGGAGGTACCAGTGTGTTGGGCTGCTCTGTGGGGAGTTGGGAAGCTGA +TTCCTGTAATATCTTATCTTCCCTTCTCTCACTTCTAAAGATTGCTATGCCATGACAGTT +TGCAAAAACTTTTGGGCACTTTTTTTTTTATTTAAAAATATTATTTTTAGCGTCTCAAGT +GATTCCTTCACTTAAGTCATAGTGCTTAGTATTTCTGCATTTACTGTGAATTCTGTTGGA +AATAGCGATGATCCTCTGAGAGACAGCTGGAAGAAAATGCAGTGGTTCCTCTCTTGGAGG +AAGGAAATGTATTTCCTGAGCAGAGTTGCTCTGCTTTGTAATCTCATGGGAATATGCTAA +TGACCCTGAAAACTGAATTTATTTTTTTAGAAACACTGTTCTGTGGTTTCTGGGATTTTG +GCTTATTTGTAAAGATGGCAAAGACTGGTTCTAGAATTCTTCACTGAGGCAAAATATGGA +AGATAAATTGAGGAAACTAAGTATTAAATATATAAATGATAATATTGGGACCTACTCAAA +AATGTGTAGTTTCTTATAATTTGCTGGATTATTGTGGCTGTTTGTTACACTAGTTTTATA +ATCACTTATAATAATTATGAAAGCTAAAGAAATAGTGATATCACAAGAAATTTTTACTTC +TGGACATCCCTCGGTGTAAGAGTGATGTAAGGTCCCCACCTGTATGCGGGTGGGGGAAAA +GACAGCCCTTATGCCCTTTCCTGCAGGTTCCAGTCAGTCCATTGATGGGCAGTCTGTATC +AGACAGATCTCTAGAAAGTCTGCAGTTTCTGCAGGATTTGTTCCAGATAAGAACAGATAA +GAAGATAAGAGAGCTCTATGGGAATAAAGAGGCTAAGAGTGGGTACAGTGCAGCTGGAAG +CTGGACCCAAAGAAGCATTTTTAGGACTCTGGAAAGACTGAGTCAATAGAATAGGATTTG +AATACTGTTTCTTTACATAGCAGCCAAACAAATTATCTAAACCTTGTTTTCTTCACCTTG +TTTTCCTTTTGATTCTTGACCTTAGGTATGGTTTTCTATATTTAAGATGGGAATATTAAT +AACAAAATTTACCTTGTGATTTTCAAACATGCATTATTTAGGAATGTGCTTTTTAAGCTA +TAACAGAAAAACAAGTTATTCTTAGGTCTGCCAAAACTTTGAACACATATTTAATGCTGA +GAGCCTAGAAATGTAGAGTAGTTGACATTTGACCCACTAGTTGGCCTTGGTAGATAATAC +AGCAATAAGATGCAGTACTAACGAATTTCAAAGATGAGTGAATTTTTTTCTTTGTACCAC +GTGAAGTACTTCCTAGAATGAGTAGCTTCTAATGTGTTATCCATATATTGAATTACAATG +AATAAAGGAAGTATTGTGATAGAATGGGAGAGAGCTTGGACTTTGGAATTAGGTAAAGAT +GGGTTTGGAGCCAGTTTCTGATAATAACCAAATGTATGATGAAGTACTTGACTGAGAGTC +TCTGTTTCCTTGCCTGTAGAACAAACATAAATATCCCTGCCTTGCAGATTTTACGCAGAG +ATGATTCATGTAAACTACCTGTACAATAAAAGATCAATACAATGCCATGATGGCCATGAT +GATCATCATAAAAATCAATTCTAATTAATAAGCTCAATTGCTGGCATAAACAAGCAGAGG +TGCCCACCACTGCACCCACTCAGTACTGGATCGCTTCTCAGTACTGGATGTAGCCTCTGC +ACTGTCTTGAGTTACAGAGGACAAGTGAGCAGGCTGTGGAGCTAAGTAGCCTGACTTCAA +CTCCTGAATGCCATTTACTGCGGTAAATGGTGGTTAATTCAGATAAGAGATTTATGCTAA +ATACAATTCCATGTGTCTTCTCAACAGATTGTATACTTTTTCTAGGACTATTTGTGGTAT +TTTGGGGCTAATTCATCTCAGATGGCTAGTCATTTGCTCCTTATGATATGAGTAGGTTAG +ATTATCATACATTGCCAAATTAATTACAATTCTGAGAACTTCACCACTTGTTAAATTACA +TTGCCTCTCACAGAAGGGAAGATAACCAAACAGATGAACTCCTGGATGATAACCATCAAG +TTCAGGCCAGTGAGGTGTGCAGATTGAAGGAGGGCCAGTTCCCAGTATCTGTAAGCTGGT +CCTCGGTGGCCTCTGTCTACTTTAGCATCTTGGATACTGCCAGGCCATGGAAGGAAGGCA +AATTGTTGCCAACGAGAATGAAATGAAATTAACATATGGCTACAATAGAAGAAATAGATT +TAGTCCATGGATTGACCCCTCCATTTAGAAAGTCTCAAGTGAAATCAGTCTGGAAACTTA +CCAGGCTTTTTCCATATATCTGTGAGTATTTTATACTTTGGATGGTCTTCCTATACACAG +AAAGAATAATGAAGGCCTCTTGATTCAGAAACTCTGAATAGCAGCTTGGTACTATGTGGA +TATTTAACAGATCAAATTCTAAGGTTAGCCTCATTTGGTCCTTATTGTCTTAAGTCAAGG +TGAATAGAATGAAGGGACACAATGTGTAACCTTCTTTATTTTCTACTTACTAAAACATTT +CAAGATCAGATCCTTTCTACTATAATAGTATCTTTTCAAATGAAGGCAAGTACAGATCCA +GAATAATAACATGTAAAGGACACTTAATGCACAGTGGAGTTTTTATAGGTGAAATATTCC +AACAAAGTATTGGTTATACCCCACCGCTAAAGAAACCACAAAATGACTGCTTAAACCAAT +TCTTCTCTATATACCTTTCCCTTCTTCCATGGAAACCAGAAACTCTGGGTCTTGTGCCTT +CCATGGTTTCTCCCTTTTAACAAATATGCCTTGTGTTCTTTCACTTACTAATTGGTGTCA +CCATGTGCTTATATTGCTAACAATTTAAATAGAGCAGTTCCTTTGAAAATATAATCTCCT +TTTAAATGCATCATCATTTTGAAGTGGTCTCATAAATTTTGTTGCTGGTTTGGGACCTTA +AACGGTATATTTATTTATATTAAAGTCTGCCTGCTGTTCGTCTTGAGATATTATATTTGT +ATAGTTAAGAGAAGTGATGAGCCAAATTTAATTTTCTTTCTACTCTGGAATGCCTTGCAT +CTTGTAATCACCATTGATTGCCTACTTACTAGTCAGAATCAATAAAAGGAATAGAGGTAA +AATTGTCCAATCTCATGTTTTGTAATATAATAGTCTAGTCAAAATGGAGGGTACTAATAG +CATTCAGCTGCATAGACATTATCTGATAATGATAGTGTGTATAGCTCAGACTACAGAGAA +ACAAATTAAAGCTGGAAGCTCAAATATTGGACTTTATTTTATTTAGGATAAGGTTTATGC +ACAAATCTCATCAGAATATGCTTTTTCCATTTTATGGATAATAATGTAATTTTTATTAGC +TTTTTATCATTTTAATTGCATTTCCTTTCAGAGACCACTAACATGTTCTACTTTTGTTTC +AAGGTTGTCTCTAATATGACTGATACATTTGCCTAAAGTCCATCAATATGAGATTATGGA +AACATTAAACCATATAGACCTGTCTGAGAATAACAGCTTTCAATTTCAGGTCTATATAAA +TAAGCAAAATCTTGGAGATAGAAGATAAGAAATACTACTAAGCAGTCAGAGACTTGGTCT +GCTATTTTTAAGCATTCACATTTCTCTACTTATTGTGCTTTGTAGATTTCAGAAAATACT +TTTATTGAGCTTAAATATTTCTAACAGGATTGTTGTTTATATGAAGTCTCTTGAACTCTA +GCATTCCACTGGGAGTAGACTTTAGATCACTCAATGATATTCAAACTTTTAGGTCTTTCA +GTAAACAACCTTGATTTTAAAAAGAAATGCAATGTGTACAATTTCAAAGCCCATCCTTAA +ATGAGCTTTACTGAGGAAATCAATCTTAGCAATTGATAAATTACGTCTTTTATTGGAAGA +GAAATTGTGCTCATGGCATTTTGGAAAACATTCAGCATGGTGGTCAAGTTCTTTTAGTGA +GTTCCCCGCCGATCATGGTCTTTCACTGTTCCCCACATCTAGAAGCCAGAACCCTTCCCC +AGATAGCTTTCAAATACAATGATTAGAGAGTGTACATGGAATAGAAATCTTACTTGTAGA +TTTTGATTAGGGATTAATTACTTAATTTTCTGTTGCCTGTTCAGGATGGTTAATGACCAT +ATGGCTTTGACATTTTTTTGCTCCTTTTTATATTAAGTTTTTCTTACTGGAAACCATGTA +ATTAGAACCACCTTTCCTATCTCATGTTCCTGTCTTCATTGGCATCTACTCTAAAGCCAT +ACAGGATTTTTGTTTCAGAATAAGAGTTGCATTAGATCGAGGGGCGGATAATTAGCTGAA +CTAATTTTGCCTGTATTGTTCTGTCACTTTATACCCCGGAGCCCTGGAGATAGGCTTTTT +AGTTATCGATTTTTACCTTTATATGGGATAAAATTTTGTAATAGAGAGGGAATAACTTAT +ACATCTAATAGCATAATGACGTAATGGGCTAGGGCTGTTAAGAGAGGGGGATTTGAGATG +GAGTCTCACTCTGTTGCCCAGGCTGCAGAGCAGTGGCATGATCTTGGCTCACTGCAACGT +CTGTCTCCTGGGTTCAAGCGATTTTCCTGCCTCAGTCTCCCGAGTAGCTGGGATTACAGA +TACCTGACACCAGGCCCGGCTAATTTTTATATTTTTAGTAGACATGTGTTTCCCCCATAT +TGGCCAAGCTGGTCTTTAACTCCTGACCTCAAGTAATCTGCCCACCTCAGCCTCCCAAAG +TGCTGGGATTACAGGCATGAGCCACCAAACCCAGCCCCTTTTCAGTTTTTTTTTCGGAAA +TGTATGTTCAGTGATAGTCATTTTTCATGCTTATTGAGTGCTTACTCTGTGGCAAGCACT +GTTCTAAATACTACATATGTTTCCTCTTTTGATCCACGCAGCCATTTCATGAGGTAGCTA +TTATTCCCCTCTATTGTATGGATAAGAAAACTGTTGCACAGAGAGGGTAAGTAACATGCC +TAAGATGATACAGCCAAAAAATTACAGAAGCAATATTTGAATTTCTCTTCTTCCCACTCT +TAACAACATATTCTAATCACATATAAGCCCAAAGTCAACTGGTCCCCATGGAGAAAGCAT +TGATAGTCGGGAATCTTTTATTAGATAAAAGCCAGTGATTAAAATGAAGTGTGGGGATGT +GCTGCTATTGAACCCACAGCTTCTAAATTTATCAACACTGGAACTGCTCATGCAGTATCA +AGCCTCATGCATGGAACAAGGGGACAGGATACAGAAAGATGGGGCAAGACCTCCAGCAGA +GTATCATGCATAAGCACAAATGAAAATGGCCCTTGGGAAATAATAGAAGCTAACTTTTAT +TGGGTGCTTTCCATGTGCTAGACCCAATGTAATGCAATGTCTTATTTAATACAGGCTTCC +TATAATTATTCCAACTTTATCAGTGCAGCAATTGGGGTTTTAAAAGGTTAGGTAATTTTC +CCAGGGTTACATAGCTGATAAATGACAATAGGGGAGCTCAACTCCCTTTGTCTGATTTCA +AAGGGCATGCTCTAGGACTTGAGATTTCAGTTCTGACACGGAAAGAGCTTAGAAGCCATC +ACTATTGTTTTAAAACCAAGAAAAACATGGACATTGAAAGTCAGTGACTTCCATGGACCC +ACTGGACTTTTTGGATCCATCAGAAACGTGGTTACTGGGCAAATCAACATCGCAAATTCC +GGAGAGACAGGCACATTAAAAGAGAAATGACCTACATCTTCATACCTAGCAACCAAGCCG +CTGGAGCCACATACTGGTAGGAACATGTCAATGATGATTTTGATGAATTGCTAAACACTG +AGTATAGACTGTTATGGATGTGAAAAATGCCAGGGAACCTCAGCCTCTGGTCCCCACACT +TTCATGGGCTTTACCTTCAGGAGCTCCATCAAGTTCTCATGGTGAAGCTTCCATCATTGC +TGTGGTTGGAAGGAATTATTGCAGTATATACCCAGAGCCTTCTCCATAACAAAGGCTTTA +ACTCCACAGTAATAGACTTTATCCTCAGTTAAGGAAAGTATACTCCTTCCACTTTTGATC +CCTTTAGCCTGCCAATCTCATCTAATAGAGAAAGAAATAGGACATAGGGGTCAGATCTTC +AAGGAAATATATTGGGAATGCTGCAGCCAGGGAAGGATATTGGGAGATGGTGGGAGGGAG +ATTAGCTATGCCCCTGGAGTAACTTTGGGAAGACTACATCCCACTGTCCAGGGCTCACTA +AGATACTGAAATTTAATCAGAAGATTATAGAATGCTCCCCTCTCTCACACTCTGCCCCCA +CACCAACAGAGTCCCAGTGTAATAACAGTGGATTACAGCTGAAAAAGCTGTAAGACACAG +AATCTCAAAGTCAAGAAGGAATACAACATCAAGGATGCCTACATGCATTTTACACATGTG +TGCACACACACACAGACACACAACAAATCTAGTCATATCATGTTCAATCTGCAGAAAATA +AAAAACAGAGAAAATCTTGAAATTAGCCTGAGGAAGGAAAACACCTTACTTTTAGAGGAA +CAAGTGAAATAATTACAGTGGACTTCTGGTCAGAAATTATTCAAGCAGGAAGAGCAGGGA +GTGAAATACTTAAAGTGTTGAATGCAAAGAATGCCAACATAGAATTCTACATCCATCAAA +GTTATCCTTCAAAAGTGAAGATTTAAGTTTTTCAGGCAGAAGGAAGAGGTTATAAGTCAG +AAAACAGGCAGGCAGACAGACCTAAGGCATATGTGTTATTAAAGGTATGGGCAGAGAGTC +AGAAGATAGGAGCACTGAAGGAAGACAGAGGCAAAGTGAAGTATACAGATGATGATCCAG +ATAGCCAGGGTTTGAGGAGCTCAGAGTGTGGTCAGAATAGAAAAGATTGCTTAAAGCCCC +TGCATGCCATCTAGGCTGAAAAATGGTTTATAATGTCATATGATTTGGCTATGTCCCCAC +CCAGATCTCATCTTCAATTCCCATGTGTTGTGGGAAGGACTCAGTGGGAGGTAATTGACT +CATGTGGGCAGGTCTTTCCTGCACTCTTCTCATGATAGTGAATGAGTCTCATGAGATCTG +ATGGTTTTAAAAATGGGAGTTTCCCTGCCCAATATTTTTTTTTGCCTGCTGCCATCCCCG +TAAGATGTGACTTGCTCCTCCTTGCCTTCTGCCGTAATTGTGAGGCCTCCCCAGCCATGT +GAAACTGTGAGTCCAATTAAACCTCTTTCTTTTGTAAATTGCCCAGTCTCAGGTATGTCT +TTATCAGCAATGTGAAAATGGACTAATACAGTAAATTGGTACCAGAAGTGGGGTGTTGCT +GAAAAGATACCCCAAATTGTGGAAGCAACTTTGGAACTAGGTAACAGGCAGAGATTGGAA +CAGTTTGGAGGGCTCAGAAGAAGACAGGAAAATGTGGGAAGCTTGGAACTTCCTAGAGAC +CTGTTGAATGTCTTTGACCAAAATGCTGATAGCGATATGGACAATAAGGTCCCAGCAGAG +GTGGTCTTAGATGGAGATGAGGAACTTGTTGGGAACTGGAGCAAAGGTGACTCTTGTTAT +GTTTTAGCAAAGAGACTGGTGGCATTTTGCCCCTGCCCTAGAGATTTGTGGAATTTTGAA +CTTGAGAGTGATGATTTAGGGTATATAGTGGAAGAAATTTCTAAGCAGCAAAGCATTCAA +GAGATGACCTGGGTGTTGTTAAAGGCATTCGTTTTTATAAAGAAAGCAGAGCATAAAAGT +TTGGAAAATATGCAGCCTGACAATGCAATAGAAAAGAAAATCTCATTTTCTGAGAAGAAA +TCCAAGCCAGCTGCAGAAATTCACATAAGTAATGAGGATCCAAATGTTAATCCCCAAGAC +AATGAAGAAAATGTCTCCAGGGCACATCAGAGGTCTTCATGGCAGTCCTTCCCATCACAG +GTCTGAAGGCCTGGGAGAAAAAAAGTGGTTTTGTGGGCTGGGCCCAGGGTCCCTGTGCTA +TGTGCAGCCTAGGGACTTGGTGCCCTGTGTTCCAGCTACCCCAGCTGTGGCTGAAAGGGG +CCACTGTAGAGCTCAAGCAGACCATGGCTTGAGAGGGTTCAAACCCCAAGTCTTGGCAGC +TTCCAAGTGGTGTTGAGCCTGCAAATGCACAGAAGTCAAGAATTGAGGTTTGGAAATCTC +TGCCTAGATTTCAGAAGATGTATGGAAACACCTGAATGCCCAGCCAAAAGTTTGCTGCAG +GGATGGGACCCTCATGGAGAACCTCTGCTAGGTCAGTGTGGAAGGGAAATATGGGTTCGG +ATCCCCCACAGAGAGTGCCTACTGGGGCACCACCTAGTGGAGCTGTGAGAAGAGGGCCAC +CGTCCTCCAGATCCCAGAATGGTAGACCCACTGACAGCTTGCACCGTGAGTGTGGAAAAG +CTGCAGACGCTCAACACCAGCCCTTGAAAGCAGCCAGGAGGGATACTATACCCTGCAAAG +CCACAGGAGTGGAGCTGCCCAAGACCATGGGAACCCACCTCTTTCATCATCGTGACCTGG +ATATGAGACATGAATCAAAGGAGAGCATTTTGGGGCTTTAAGATTTGACTGCCCCACTGG +ATTTCAGACTTGCATGGGGTCTATAGCCCCTTTGTTTTGGCCAATTTCCCCTATGTGGAA +TGGCTGTGTTTATCCAATGCTTATTACCCCCATTGTATCTAGGAAGTAACTAACTTGCTT +TTGATTTTACAGACTCATACTTGCCTTGTCTTGGATGAGACTTTGGACTGTGGACTTTTG +AGTTAATGCTGAAATGAGTTAAGACTTTTGGGGACTGTTGGGAAGGCATGATTGGTTTTG +AAATGTGAGGACATAAGAATTGGGAGGAGCCAGGGGTAGAATGATATGGTTTGGCTGTGT +CCCCACCCAAATCTCATTTTGATTTCCCACATGTTGTGGGAGAGACACAGTGGGAGGTAA +ATGAATCATTGGGGCAAGTCTCTCCTGCGCTGTATCTGTGAGCGTGAATGAGTCTCATGA +AATCTGATGGCTTTAAAAATGAGAGTTTTCCTGTACAAGCTTTTTTTGCCTGCTGCCATC +CACGTAAGATGTGACTTGCTCCTACTTGCCTTTCACCCTGACTGTGAGGTCTCCCCAGCC +ATGTGGAACTGTGAGTCCAATTAAACACTTTTTTTTTTTTGTAAATTGCCCACTCTCGGG +TATGTCTTTATCAGCAGCATGAAAATGGACTAATACATAATGCTTTCCATATTCCTGGCA +TTGTCTTGTATTAAGGTAAAAAAAAAAATGAATACGATGTGGCCCATACACCTAGGAAGC +TATGCTCCAGAAAGAGGCGAAGACAAACTGTTATCACCCAGTTCATTGATTTGTTCAACA +CAGGATTTTTTGAGTGCTGACTTTATACCAAACAAGGTAGTAACTGCCAAAATGAAGAAG +TCTAGAAAGTGCTATGAAATCACAAGTCGGGGAGCAAATATAATGCCTAGGATTGTGAAG +GAAAAGTATACATGGATAACAGGAGAGTTAGGCCTAGAAGGAGTAGAAAGTAACAGATAA +GAAGCTGAGCAAGCAACATAGGCTGCCAGAATGTAAACAATTTGAATGGCAGACATGGAG +CACTAGAAATATCTGATTTAGAAAATTTAATGAATATTTTATACTTTGTCTCAAATCAGT +CTTCATGGATTATATAGCAAGACCCAGATCAAAGACAAACAGTAGATTGGAATGGAAATG +AATGGGTGGGACAGGTTTGACATCTCATTTTGAGTTTAAATATCAGATCTGAAGTACTCC +ACATTGTTCTACCATTTTTTGGAATTAACACCTGAGATTAAGCCTACTGGACATTCTTTA +TCCAAGCAAGAGTAAGAAGGCTGTTTTCTGGAGGATTGCTGTCTCTTGGCCAGAGATTAA +ATCCTATCATTCTGAAAACCACAGCAATGATAGATAAATAATTCGACCAAAATCCAAACA +TTGAGAGCTCACAATTTGTTATTAAGTCTATCAGACCCCTGACTGGTATAGGCCACTGGA +GCCATGATGTTTAGTTATACTAAAGAGAGAACAAGAAGCCATCACTGACTTCTGGTCAGG +TTGGCTTAGAGTTGGGGTGTGGGGCAGAATAGATTAGGACAATAGCTTGGGACAGGTGGT +TAAATAAAAAAAAAATGTCCTTGATAGTGGAGGTGGATCTCAATATGAAATGAATCATGA +AATAAATTGAAGATAATACTAGGATCTCTATAACTGTTCTGTTCAACAACAAGGTCACTA +GCCATTTAAATATAAATTTGAGGTAATTAAAATTACATAAACACACAGATCATCAGTTAC +ACTAGTCACACTTCAAGGGTTCAGTAATCACATATACCTGTTGGCTACCATGTTGGACAT +CACAGACATAGAACATTTCTATCAATGCAGAAGGTTCCATTACACAGTAATGTTTTGATG +TATGTGAGGTATGATGATACAATAGAGAAATGCAATTAATGTCTTTCAGAAACAACTACA +AAATTGCTTTTTTTTAAAAAAATGTTTATATTTTGGAAGTGAATATAGTAAAGGTCTTGC +AGCATAATGCCGTACTTTGCCAACAAACAGTTTTAGGGATGTTTATCCCTTTTGAGTGGA +ATATCCTTATTTTTTTTTTTTTTTTTTTACACATTACGATATTTAGTTTTAGTGAAGTCA +GGTCACTTCACACTAGCAGTAAATGGTGACGGTCAGTAGTTGAAGTCACGCTGCTTAACT +CCAAAGCCAGTGTACCTGACCTTTGCACTCCAGAAGAGCCCAGAAGCCACCTTTGGGACT +GAGGGGCCACCTGTGGTGTAGTAGAGGGCAGACATCTCTGCCTGTTTATGCCAGAACTGA +ACTTAGTAGTGAAGGTGTCCATTCTGCTTGTGCAGTGCCCTGCTGCAGCAGTCATTTGAT +GTTGTAATATCAGTTTTGCCAAAAAATGTGCACATTCCTCTGCAAATCCTTCTTGTTCTC +TGAAAAGCATTGCATGTATTAAGTGCTCTTCATTAATACCTGGCTATCTGTTGGGTGTTC +ATGAGTCCAGTTTGATTTTCATTGTTCAGTTAGTGAAAAAAGGTGAACAAACTATATGCA +ATATGAACACACTAGGTTTTTCTGTAGTGAAGATTGATGTAAATTTAACCAATTAAAATA +TTTTAACAAATAATTTTGCTGCCATATGCTGGAAAAATTGCTGAATTTCTCAGTTAATCA +GAAATTATGTGAATTTCCTTCATTTAACCTAGGCTCTGTACTCTTAGTTTCTTAGTTTCT +TTTTTTGGGAGATGACAGATCTAAAACGAATTTCTTTAAAATCACTTCGGATTTTTTTTT +GAAGTACTAATTACATGATTCCCTTACTTTTTGGAAGTAACTATTGAGATTTCTTCATTT +AAAAATATTTTTAATAGTAATAAAGCAGATCCTTACTAAATATTTTGGGACTGAGGAATT +TCAGATAAAATGCAGTTTTCAGGCTGTGACATGGACCTTCTACTCTTTTGGAAAGCTTTG +GATCATTTGTGATTGACAGTTCAAAAATACAGTGATATGTTTTGTCTAGCCCATGTCATG +CTGGAGAATACTAAATCAATAGTAATGTTATCAAAACCAGAAATCAAATGCAAAATAGTT +CCCTTAGTTTCCTGCATAATGACATTTGCTCTTTTGATAAATTACTAATGGGTTCTTGGA +CAGGAGACCTCCTGGAACAGCCAAGCCTGGGTATAAATGGAAAGGAGGAAGCGGTAATAT +TTACTATACAGAAAAAAATTGCCTTCAGTTAATGTTCTGTATAATGTCCAAATATAACTG +AATTCCGCATTGTGATAGGATATTAGTAAAGAGGCCAAGAACAAGCTAACCATAAACCAC +AGTGTTTTAACCCTACTAAAAGTAGTTTAGAGCGTCCTGCACTAAATCATGCATCCTACA +ACCAGAACAACTCAAACAGGACAAAGCATCAGTGACCAAAGCAACAGAATGCCAATAGTT +GTGCCACAGTTCTACCTGAAATACCCTGTTCCCTCAAGAAAATGCAGTCATTGGCACAAG +GGCATCACTACTATACCATGTTTTAAAAAATTTGATTGCTTAATTCAATTTGGGGGATAA +CTTGATGCCAGGAACATATTTTAGGGCAAAAAAAGTCGGGAGGGAGTCATATAATTGTCT +TTAAAATCTTGAACCATCAGTTTTACTTTAACTTCTCGAGAAAAAAAATCTTGAACTGAC +TTAAAAGAGTTGTGACCTCCTGCATCACCGTGCTCACAGACGTTTTAGTTAAAGTTTTGA +TTATGAAATGTATCATACATATATTAGAGTATGTTTGATCTTTAGGCCGGGCATGGTGGC +TCATACCTGTAATCCCAGCACTTTGGAAGGCCAAGTCAGGCAGATCGCTCAATGAGCCCA +GGAGTTCGACACCACCTGGACGTCATAGCAAAACCCTGTCTTTACAAAAATACAAGCATT +ATCTGAGCGTGGTGTTGCGTGCCTGTAGTCCCAGCTACTTGGAGGAGGGGGGGTGAGGGG +ATGGGGTCAGAGGAGTGGTTGGGGAGGCTTGAGGTGAGAGAATCCTTTGAGCCCAGGAGG +CAAAGTTTGCCGTGAGGCAAGATTACACTACTACACTCCAGCTTGGGTGACAGAGTGAAA +AAAAAGAATATGTTTGATCTCGCTCTCTCTCTCTTTATCTCTCTCTCTCACTCTCTCTTT +CTATATATGCATATATTACCTAAAAATTTTTATGAAGTATATCCAAACACCGTCTAACTC +AAAGGCTTTAGGAATCTGTGGTAAGAGAAAGTCTTCCAACCACATAGTTGTATTAAATAG +TATAACAATTGCAGATTAGCCTCTGAGCTTTACTGAACACCAGATAATACCATGTAAGAT +GTGTTAGGTAAAACAGCAAACCAGTCTGTTTCCTACACTTGTGGTCTACAAAATGAACAT +ACCTAAAGCTTTGGATTCACTGTCATCCTAACCTTGTGCTGTACTTATAAGGTAGTTGCT +GTATTTTTATATAGAAAATGAATAGGAAGACTTGCTTTGCTGCAGTAAACAAAAGATCTC +TTCCCTCTCTCCACTCGACCACCTCCTCTCCCTAATGTTGTGGCTGGAGCTCACTGAGCT +GCCGAAGTGGGAACATTTGTGCTTTGAAATACCTTTGTTTTGTTGGATTTATAATTTAAA +GGGGAAAAATTTTTATACTGAAGAGTTGAATGCAACCAGAGAACAAAATAATAAAAAGCC +TTATTTGAGAAGAAATAATTCTTTGGAGTAAGAGGTTAGCACATGTCAATATGTCATATA +CAGGGAAAGTGAGCTTTTGATTACTTAGAGGTAAGGTTGCCAGAGGGTTTTTGATTTAAA +TTTCTAAGGCTTGATCAGAGCATCAAGGGGTTTGTTGAAAATCCTCGTAACTTGTGAACT +TGACTTTTATTCCTTTGAAAAATTATACAAAATATTTTTTGCCCACATTTATATTCCATG +TGGCATGTTTCTCCTTGTAGCTTTGCAGCTATTCCTGTGCAGGCTTTATACTTGTTATAA +CATCAGTGGTTGAATTGAATTTGAACATTGCTAGAAAAAAAGCAGAAAGTTTTGAAAGAG +GAAAAGTGACCCAAAAGTTGGCTCTAAAAATGTTTCAAGCTTGCAGAATTCCAAGGAATA +ACCTAAATGAACACGAATAGGGACTATTTAAATAAGTCATGGCACAACCTTAAAATGGAA +TCCTATTTGCCGGCTTAAAAGATCAGATCCAAGCTATATTGAATGAAAAAGAAAAGTCCC +ACCACTGTTAAATGCCTTGGTTTGTTCATTCAATATTTTGATGTACCTACACATAGAATA +TATTTCAATGACAGAATTGTATAAGTTGGTTGTGCTGGGGTTTTTTTTGTTTTTGTGTTT +CGTTTTTTGAGATGGGCTTTCACTGTATTGCCCTGGCTAGAGCGCACCAGCTGTTCACAG +GCACGGTCGTAGTGTGCACTGCAGCCTTGAAGCTGTCCTGCCTCAGCCTTCCAGTAGCTG +GGACTACAGGTGTGTGCCACCACAGCTGGCTTCTTATGCTGCTCTAGAGAGAGGGAAAGG +AGCTATGTCTCAACAGACTGAGAGTTTTCGTTTTTTTTTTCAATATATGACTCTGCACTC +GAATCATTTTAATGTAAGGATAGATATACCGATAGAAGAAAACTATTCAGTTCCTTATGC +CCTCACTCTTTAAATATATTATTTTTCAAATTTTGTTAAAACTAGGCATTTTGTCCAGTG +AAGTAAAGTGGCTACAGAAAATGTTAGGAGATTTTGTTTTATTTTGACATGAAAAATGAA +ATTACAAACAAACTTGGAGGCAAATTAACCACTTAGCAATAGAGCATCTTTCAATCCATG +GCAATAATTGCTGGAAGCTAAAAACATGCTAGTATAATAAATACATTTGAAAAATACACC +TATCATTGCCGCTAATGTGTAGGTTACTAACTTTATATATAATGTTGCCTGTTGTTTAGT +TTTATATATTTGCTTTATATACATAGAAACCAATAAACAAGAGTATGAGTGTTACCTACA +TTTGCTTATCCTGTGGAGACAAAGTACTAATAAAATAGATACAACTTAAAAGTTTGAATG +ATTTATTTTTCTCTTATGCTGCCTGTAACTTCTAAAACTCATGATTCTGAAAAAGTAAAA +AGTGTTGACAATTTTGTTTCCCCTCCAAATCCCCATCATTTTAACTTGTTCTGAAATGTG +CCACGTGAGGTATCCTGTATTATGTGCCCGCATCTGCTGCTCCATACAAACCGATGCTGC +TGTCTTAGAAATAATAGGCCCCCTTTTATTCCCTAATAGACACTGCCATTATGTGAGATC +ATGTTCAAGCTTTAAATTTTTCCACTCTGTATTTCTGTTTTCAGTTTATCTTATGGAATA +AATGGTCCATTATTTCAGTAATTTTGTATATTGTTATATTTTTGAGTTTCCTTTCTCTGT +GTCTCCCTCTTCCTTCCTCCTTCTCCTGCCAGCTCAAGGTGTTCTCTCCCTTCTTCTCTG +TCTGTCTGTCTGTCTGCCAATCTAGCTCTCTCTCTTACACATGCCTTACACAGATCTTCT +GAATGAGGTGAAGAGTGTGGCGCGAACAGCAGGACCTTGACTGTGGCACGGTCTGGACTG +TGCATCTTGCACTGGAGAATTTAGCTGTCACTTTGGAGCCTGATAGAACTAGTGTGCAAT +TCACATGCCCCAAGTCCTGAAAGGGAAACTGCATCTGGTGTCAGCGCAGTTCACTGATAA +GATTTTATCTTTTCTCCTGCTGATACTGATAGAGCCATAGCCAGGTGAGCAGTAAATAAA +GAAGATTTATTGTGGGCTGGATTTGTTAGCTAACAGAACTTTCTCGGAACTGTATCAAAA +AAAGACCCATAAGTGTTCATCTTTCACATCTATAGAGCTCAATAATGAATGATGTGGTGG +GGGAGGGACAGCGGCAGGAATTTATCCAGGCAAATTCCTTTTAAACAATAAACACTTCAT +ACACTATCAGGCTAATCTGAATAGATGACTAAAAATCCAGTGGTTGATAAATTATCAGCA +TGGCACCTGCATCTTATGCTTGAAAAACCTTGAGCAAACCCAGGGCTATACTTGTGGATT +AATTGAGCATGCATAATTTACCACTGCAGTTTACGTAAGTGTAAGTATTTTTCTCATTCT +GGTAAATAGGCATTTCCAGCTTCAGGAGAAAAATCAGAATGTTGCTGTACAAAGAAATGA +GCCATCAGCCTATTTGGCTATTATAAGAAAAAAGAATCTCTGCTCTTGCCACCACTGCTT +AGTTTTTAAATTGAAATGATTTTTCAAGTTTAATTTGCTTTTCTCCATTTATGTATATTT +CTTTTTATTCATATTTATTGTCTTGCTTTTACTATTGTTTGTAATCAATACTGTTTTCTT +AGTCTAATTTGATGCTACTTATTTGAATGATTTACAGAACGTTAATCTAGGAAAATACTT +TCATTGCAGTTGTTTTATGTAGCCAAGGGTGAAAAGCAAATGCGTAGGGATTAAGAGTCA +CAGAAACACATCAAGGTTTGAATGGCTTGCTGCGTATTATCACCCATGCGCTTTTTAATT +AGGTGTTAATACTAAGTCACTATTTTCTCATCTATTAAATGGAAGTAATACCTATCCCAA +AAATTGTTCTATTACATGTTATAATGAATAAACAGCCTCATTTAAAGCCAGAAACATACT +AGGTGGTCAATAAATGATATGTATCCTTGTAATTCTCTTATTAAAACAAAATTTATTTCA +TATATATCAGCTGTAAATTTTACATCCCTAGATTAGTAGTTTAAAAACATTTGTTGCTAT +AGGAGATTTTATTTAATTATTATTTTTGTTTTGTTTTGTTTTGGAGACAGAGTCTTGCTC +TGTTGCCCAGGCTGGAGTACAGTGGTGTGATCTCCGCTCACTGCAAGCTCCGCCTCCTGG +GTTCATGCCATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGACTACAGGCACCTGCCACC +ACGCCTGGCTAATTATTTTTGTATTTTTAATAGAGACGGGGTTTCACCGTGTTAGCCAGA +ATAGTCTCGATCTCCTGACCTTATGATGTGCCCACCTCGGCCTCCAAAAGTGCTGGGATT +ACAGGCTTGAGTTTATTTAATTATTAGTAGTAGGCTATACAATATAAAGTCAATATGAGA +GTTTTATTCTCCTTGTTTAAGCAAAAAAAAAAAAAAAATGTCCTTGTGGGAAAGGAAAGC +TTAAATGCAACTGTTTTTAAATGATACTATTATAAATATATTAATCCCTGTTTTACAATG +GGGAAATACCTTTAAACCTCAATTGATGTAGTAGTCATAATCGTGAGTGGCTGGGTTTCC +ATTTGATTTTTCTCATCTACTCCTATTTCCTGTAATATAATATATACATTATAATTTTAA +AAATGTGTTTTACCTATGCTTAATTTTTTATTGCGGTAGCTACTAATGCTGAAATCTTAA +ATTTTGCAATCTCAGAGCCCCTGTATAGTAAGTTATAAAAAATGTAAATATAATAGGAAA +ACTGACTACTTAAAGGAGCTTTTCAGTGAATCACACATAAAATCCAAGATCCTGTTTATA +ACAGAGGTTAAATTTATTTATATAGTAAATCTAATTTTTCATGATATACAACACCCATAT +GTAAATTGTAATAGCCATCGTACGCTTCCTTTCTTGGTGAGAACTACAGCTATCAGCCAG +GCATCGGGTTATTCCTATAAAGACATGTCACATTATCTGCCACTTCTCTGTGGCTTTATT +GATGTGGCTGTCACCCTAGAAACCCAGCGGATTCGGAGATGAGGCTGTCTTCCTACTTGA +TTTTTCACTAAAGTACATTTGAGGAGACCACTGTGAGGCTCTGGTGGAAGAAGCCGAAAG +GGTAATTCTCCATAAGAATAGTTGTAACCTTCTGAGACTTTGTGTCTGCACTCATGCAAT +TGGTCATTTCCTGAATACTAAGTGGGACTTGTCGCACCATTAATCATGCCACAACAGCAC +CCTCAATCTTGCTTAGAAATAATCATTACTTAATTAGCTGGTCTTTTCTTTGTGTTTCTA +TCTCTTTCAGTCGTAAGTTTAAAATGAGGCTACAGAGTGATGAAAAGGAGAGAAACAAGC +TAAGAAGATCATGTAATGGCTAGCACAGAGCTTGGAGTTAGATAGGCCAAGTTTCTCTAC +TACTGATGAGCTGTATCATGCAAAGTCATACAAGTTACTTAAAATACTTAAGACTCTGAT +TCTTCTTCTGTAAAGTGAGTATAATAACGTCTTTCAGTGTGTGTTAGTGAATTCTTGACA +GACCTATGCTCGAAAACATGGACCTTCTCTTCAATTTTTGCCTTAATACTGTGAGTTTGG +GTCCCAATCTTAGAACTTGACCTTTTCCCTCCCCTCCAGATAACATGATCAGCTTTTCTT +TGTCGGGTTCCTGAATGTCAAACTTGTAATGCCAACCATTTGCCACATAAAGGAGAAGAT +CTCATTTACTCCTAACAAATGAGTTATCTTATAAAAAACAAAAACAAAAAACCAATATCA +ATGTCAAGTGAAGCAAATCTCAGCTGTGGGCTCCATCAGCTATCCAGACCTTGAGAAGCT +TTGTGGTTCTCTGCTCAGTTAATATGTGTCTGACACCCACCTTTTCAAGTGAAGCCAGTG +CAGTGAAGTCAGTCTGGTGCTGCACAGATGAGGTGAAAAGTGGATGGAGAGGCTCAGACT +CACCAACTACAGTTGTTCCTTCATTTAGATAGTTGTAGAGTTCCCATAGAACTAGGAGTG +GTCATTCAAAATGATCCCTTGCCACGGTAGTAGACTTTTTTCTTTTTTTCTTTTATTTTT +TAGCAATCCTACTGCCAACATGCCATTCTATTTAAATGGAAAATGCCACTGTGTATACTA +TTATTGTAATAAGGTACCTTGTCTCCAAGTCAGAAGTTAAGAAAGAGAAATGAAAGTTTT +CAGGCCTCTTGGCAGCTGGGGCTCAGTCCTGTGACCTTGCCTTTGTTAACCAGATCATTC +TGTTTGGGGTCTTGACTCCTGAATGAGAATGGTGAGGATTCATTCATGATCACTTCGATG +ATGGCAGTGGCAGCATCATGTCACAATGCTATTGGGTTCACCTATGTAATACGATGTCTT +CTCCAATTTCTAGAGGGAGTAGCAGGTGGTGAAGCCAGTTTTTGGTTTAGGAAAGTCTGG +GATTTGTAGCTGCCTTTACAAATTTGGTGCTCAACAGACATGAGAGGTAACAAGGAGTTA +ATCTTACTAAGGAACTAAGATTACCTAGCGTACTTTCACTACCCACTTGTCCTCAGGTCT +TCTGTGATTTAAGACAAGCATTTTTCATTGCTTTTGGCCACCAAGTAGAGTTCACTGAAT +CTATAATGACGATCACAATATAAGCGATTTTATTAACCTGTCGGTTACTATACAACTTTC +TTATTCTGGTCACATCCCAAATCCAGGAGGGTGGTGAAAATGCAAGACTGTTCTTTATTC +CCAAAGTACTGAATTTCACATCATTCTTTCATGAATGGGCACAGGTATACTTGTATGTAT +ATCTGGCTTATAAATCCTTAAGAATGTTGGTGGTTTACTTCATCAGAGGTTTATTATTAT +TGATTGAAATGTAAAAGTTAGGCCGGGGGTGGTGGCTCATGCCTATAATCCCAGAACTTT +TGGAGGCCAAGACAGGCGGATCATCTGAGGTCAGGAGTTCAAGACCAGCCCAGCCAACAT +GGTGAAACTCTGTCTCTACTAAAAGTACAAAAAAAAAAAAAAAATTAGCTGGGCATGGTG +CAGGCGCCTGTAATCTCAGCTTCTTGGGAGGCTGAGGCAGGAGAATCACTTGAACCCGGG +AGGTGGGGGTTGCAGTAAGCCGAGATCACACCACTGCACTCTAACCTGGGTGACAAGAGT +GAGACTCTATCTCAATAATAATAATAATAATAATAATTTAAAAGTTAGTTTGGGTAAGGC +CGGGCACGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCTCAGATGGGCGGATCA +CCTGAGGTCATGAGTTCGAGACCAGCCTCAACATGGAGAAACCCCATCTCTACTAAAAAT +GCAAAATTAGCTGGGCGTAGTGGCGCATGCCTGTAATCCCAGCTACTCTGGAGGCTGAGG +CAGGAGAATTGCTTGAACCTGGGGTGCGGAGGTTGCTGTGAGCCGAGATGGCGCCATTGC +ACTCCAGCCTGGGCAACAAGAGTGAAACTCCGTCTCAAAAAAAAAAAAAAAAAAAGTTAG +TTTGGGTAACTATATGTGTATTTGGACATTATGTCTAAGACACTATTATTTGCATTGTTT +CCTAGAAGTTCCCCAAATGTGTTATTGTGATGAGACTACCCTAAAAATGGGTTCTGTGTT +CATATGAGTTTTCAGAGAACTACATAAAATCTCTTTCTCTTAATAATCCACACTGTATAT +TAGCATGTTAAGGACTTCACAATTCCTGAGAAAATGAGCTTACTTCACATCGTTTGACTC +AGAGTTTTACAAATTTGCATGACTACAAAGACCCTTCCTGTAAAATAAAAACTATGGGAC +TAACACTTTATGAGATATATTTTGGGAAATGTTACCATAATATGCATTTTTCTATTGTAT +TTTTCTGCATCACATGTTTTCACCAACAGATGCACTGGGCTTACATGGGAGAAGAGCAGG +TACTAACAGAGATATTCATTTGTAAGTCAATTCATTCCAGTGGTCCTTCCCCATGGTGAC +AGTCTCCCATGCAGTGTAGGGGCAGGGAGAAGTGCTTTTCTTGTTATATAAAAGGATCAG +AAACTTATTTATTTACCTACATTTACCTACAGTCTTTGATGAAGCCTTCCTTGGCACAAA +TTTATACCTTTAGACATAGGTCCAGATTGTTACTGTCTTCATAGATTTAATTCACTGATT +ATTTTAACCAAAGAGGTCTCCAAAGTGATAAGATAATGAGATGGCTTCACAAAGAATGTA +GAAAACTGAAACCTCTTCTGGTAAAAATACAAAGAACTGTATGAAAATGATACACACCAA +ATTCAGGATGGTGGTTACTGCTGCCAGGATGTGGGAGGTGGTCAGGAAGTGATACACAAA +GGAAGGCATGGCAGGTGTGCTCCTGGGAAACACTATGAAACCCTGAGGGTTGAGCCCAGG +GCAGCCTTCAGGAATGCTCTCAAGAAAGACAGCTGTGAAAACATGTGGTGTTTGGTTTTC +TGTTCCTGTGTTAGTGTGCTGACCATGGCACATGTATACCTATGTAACAAACCTGCACGT +TCTGCACATGTATCCCAGAACTGAAAGTATAATAATTAAAAAATAAAAAAAATAAAAAAA +ATAAAAGAAAGACAACTGTGAAAGAAAAAGGGAAGAAGAGAGAGGGAGAAGCTGAGCTGT +AATACCTTTGCAAAACTGCCTTCAACCTAACTCTCGGTCCTTCAGAGATGTGTCCAGAAT +CCAGGCAAGAGGGTCGGCCCTGCGTCAACCAGTCATTGGAAGTGAGCTGCTCCTGGAGAG +GAAGAGAGATAGGGTGACCTTGGTCAAGGCAGCTTCAGCTGAAAGCAGCCAACCCGCCAG +GCAACTGGTGGAGTGGGTGTCTTGGTTCTGAAGTGGGAATCTGGTAGCATCACTCTATGC +CCTTCAGAGGATTTACCACCACTGGCAAATTTGTATTTGTTTAAATACAACATCTATATT +TTATTAATAAAATTTATTTTCATGCATGGTTATTCTTACCTTATTCTTTATATCTTGTTA +TTGTCTTCAATCATGCAAAATAAATTTTAAGAACAAAATGTTGAAAGAATACATTTATCA +TGAAGAAATTTCATGCAGTAATGCTTCAAATCATTCCAAATCACTGGGAAAAGAATACGT +TCTGCATGACTGACTCTTCTAGTTGAAAGATTTACCTAAATGCCAAAACTTTTAAACACT +ATTTTTAAAGGAAATCTTACTAAAATCTTGCTCATATATCCATATCTTAATGAAAAGGCT +GAAATGTGCATAATAGAATCTTTCCTTGATGAGTAAATGTTTTTATTAGTTTGGGTCCTC +AAATATACTTTGTAGAAACTCGTCTTATCTCCCCCTCACATACAATTAATCTTTGTTTCT +CTACTTGTATTCCAGCCAAACCATTCCCCTTTTTGGCTTTTAAACTTTTTTTTAAATTGG +AATCACCATTCTCAAATTCCCTTAGGTTTGTAATCCAGAATCAGCTTTACCTCTCAGCCA +CTCCTTCACTTTTGCATCTAGTTAACAAATTGGTCAACAAATCCCACAAGTTCTGCATCT +TCACTACTTCTAGCATCTGCTCTCTCTTTCTATTCCCTGGCCATAAAACCTCTAACTGGA +CTAGTACATTGGCATCTAAATTAATGTCTCCAGTTGAAACTATCAGACCAGTCTCCTACA +ACTCAACTCTGATCATGTCACTTCACTACTTAGAATTCTCAGTGGCCAGAAGCTAGACAG +TAAGGGCCCTTCCTGTCCACTGTTGTCTTACTTTGTCTCACTGTTGTCTTACTGTTGCCA +CTGACCTCTCCAGTTTCTCCTCCCACTATTTGTCCCTAAGCACATTAGTTTCATCCATAA +GTGCATAGTTTATGCTTTTTCAGTCTTTGCTGTTCCTATAATCTGTGGGCTCCTAAAGGC +AGAGGAAAGCCTACATACCAAAATACTGAGAACGGAAGGGTATTTAGTTTAAGAGAGTAG +GCTCTGGAACCAGCCTCCATGGTTTACTTCTATCCACTTACTAATTGTATGACTTTGAGT +ATGTTACTCAATTTCTTTCTGCCTAAGTTCCTCATTTGTAAAATGAGGACAGTAGCATCT +GCATCAGACGTTGTGAACTAAATGGTTCATAGATGGAATTGCTTAGAAGACTGCCTGGCT +TATAATAAGCATTCTATACATTTTGTCTATTATTATTGCTTTTGTTCAGGCCAAATTAAA +GTCTTCACTGGCACCTACTTTTATATAGGATCTTTTACTGTAGCCCCATGATGCATTGTC +CTTTTAAAGCCATTTGCTGATTTGCTACTTGCTAATTGTATGTCTGGTCCCAGATTTTTT +AATTTGGTGATTCCTTCCTTTCCTAATTCAGGAAATGTATTTTATCGAAAGTCACGGAAA +CCAGTGCATGCAAGCTTAATGTTTACTGAATGGCTCCAACAGGTAATCATGCCAATATCT +AAGAACAGGAAATTGCAGACAGCTAGGCCACATGGGATTAGGCTGAAACTTCTGTCTGTT +CTAGGCCATTTCACACTGTTTTAGTCTGCTTCTGGGTTCTTTCCCTAGTTCTCTTAGCAG +ACTGACTTTCTCTGCTCAGTTTTGCTGTTTCCCCCTATTCTTCTTGCACATGAGTGGATT +GAGTTTGCTAAGACACTGATTACTGCTTGGATATCACTTGGCTTTGCATCTGGGCTCCCT +ACAACTAACAAACACAGTCTTTTGGTATCTGAATTCCAAATTCTTAGGAAGTAGTATTTT +ACTGGCTCAGGTGGAATATGGTTTGGTTCCCTAGATTAAGTGCCCCCTTCTATTTCAGTT +GCTGTAGTCAAAGCTATAGCTTTATCTGATTCAAAGATAATAACTTAGAATATCCCTCCT +ATAGCGGCAGTGGGTGGGGAATATTACCATTACCAAAGATGGGCATAGGCACAGTGCAGA +TGCCACAAAATAGGCATGGATCCTGTCACCGTCTTTACTGGAGTAAGATATATCTTAGTG +TATTCTTGCAGAATGCCTGCTTTCTTTACTCTCTTTTGCCACTCCAGAAGCACTAAAGAA +TACCAGGGAAAACCTATTGGTACCAAGTATTTTGAAATCCACTCTTAATTTCATGGATGT +TTTCCAGAACAGACCTACAAGTCTTAAGGTGGTTTCACTCAGCTTTCATGGGTTAAAACA +GTCTTGAGAAAGCTCCTGGTACTCAGTAGAGTCTGACTTAAATTGAGGCTTAATGCCACT +GTACATTACATTCCTGAGCCACATGTTTGTTATAAATGCAGTCTGGTGACTTTTTACTCT +TGAGGGCAGCCACACTCCAATAAAGGTTTGGTCTTCATGACATAAGGTGAAGTTCAATGA +TAAGAGTTAGCTGATAACATTTGAAATTATTGAATTTGGAATCCAAGTAAAGAAACAGCT +AATAAGGAATATATCTTTATCCTTTTATTCTAAATTCTCAGAATTAGCTTCCATGTCACC +CATTTTCCCCAGAAAATCAGCCAACTCTTGTAACCAATTTGTGTGTCACAGGTGTTAGAG +AAGGGTACTCTTTTGGCTCTATTTCTCATTTCATTTCATTTTCATTTGTTGGGGCATGTA +TAATTAAGTTTACCTGCTCTTCCCCAGAAGGCAATTATTGGTTTAGATTGCCTTATAATT +GTCTCAGGTCTTTAATGGCTTCGCTGATATTTAGCAGTGTTGCTCCTGTTTCCTCTTTTA +TTTTAAACCATTTGTCCTTTTTGTTTTACCCTGACATTGATCTGTGTTGTTCCTCTCTGC +AAACAAAAGAACCAACATCCCACATTGCATAAACATTTGTGTCACACTTTCCTCTCGAAA +TTAGTATTCTTTTAAACTGGTTAACACATTTGTACTGTCTCTGACACCTTTAACTATGAC +AACTATGAAACAAAATAGTGAACAGTGAACAAACACATCACTGAAAACCGATTAGATTAA +TTACTATTCGGGACAGTGCTTAGATTAATTATTTTGTTTGTGTAGTATGTTCGTTAAGTG +GTTGCCTGATTGCTGCTTAGAAGATTGATTGCTTCTTACATTTACCTTGTGGATTCTGTG +GGGAAAATATCTTTTAGGATTCATCACTTCTCAAAGCCCAGGGGGCTTTGTTGACATGAG +AATGCTCCAGTAAAGCTGTAAAATGGAGAACCAACTGAGGAAAATGTGTTCTTTAAATAA +ACACCTACAGTGGTGGCTAGAGTAGCCATCAGATCTGTTTAACATCAGGAGAAACAACTG +ATGATAAAATTGAGTTAATACGAACTATACAATCTGAAAACCCAGCACACCAGCTGGATT +GTAAAATTGAGGTGAATAAGCACTTACCAAGATTTTCTCTGTATCCAGTAAGCTAAAATA +ACAAAGTCTTGGTGACTTTATGCTCATTTTACCTCTTGACTGTCATGTACCTCACTTCCC +AGTAGCAGCCGCATGAGGACTGCTGCTGCTACTGCTGTTTGAGTCTGCCCTGGCAATGGG +GCTCAAGAGCTCCCCGGGCTCCTTCTGAAGAATCCACACCACTGCCCTTTGAGGCGCTTG +CCTCGCTGTAGGAAACTTCATGGGGTTATGTGATGCATAAGAGCATGCATTATCTACTGT +GTTCAAGGGGTGACTGCCTGCACTAGGAAAGGATTTATGATAATAGGATTTTGTGCAATG +GGGAATCGTAACAAATTTAAATAGAAGAGTACTTTTGAAAGAAAAAAAATGAGTTGAGGA +TTAAAAATAGAACAGACTTTTGTTTAGTGAAAGACTGAGCTAATCTCTCCATTTGGGGAC +ACAAAAATACATTGCTTGCCCATGATTGTGTATTATACCTATCTGTGACTTTGAATGCTT +ATGGCGGTATTAGACACACAGCTTTAGTATTCAAAGAGGCTTCATACATCCCTGCCAAAA +ATACTGTACCTTTGTCCAGAAGAGAAAGACTAAAGAATCTTTCTATGCTTCTAGTCTTTT +GACCTTAATATTTGCATCTATTAATTATATTCATAAACAACTACAACACAATTACACAAA +ATACTTAGATGTAGGGCACTGAAAATACCTAGGACTTTTAATACTATAGATTAAAACTAA +GGAAGCATTATAACTAATATGCATCCCAGCAAATGAGAAGGAAATAACCAAAATAGTAAA +ATAATTAAAATAAAAGTTGCCTCATGTTTTAATCAGTCTTCCCTCTGTAGCTTGAGATTT +CAGAAGGTAAGCTATTTACAAACATAAAATGTTTTTAGCATTTAAAATCATTTTGAACTT +AAGATTATTAAACATCGTAACCATCATGTCATTATGGCAAAGATAGTTTTCCTCCATAAA +GACACAGTCATTGCCCAAAGGAGAAGCAGCCAAGAGCATAGGTATTAGGACAGTGATAAA +TGAGAGGATGAGAGATGGAGTGGTTGTTTGTGATTTGGTTGGCTTTCTACAATGGTGCAA +AGACTGAAATAAAAGGAAATGCATTAGCCCAGATGAAAATATATTTAAGGCCTTTTTGAT +TAAGTTCTTCTTTTCCTGTGTGACTTGAAAGCTGAAACTCGATGAGAATTAATTTTTTAA +ACATCTTTCTTTCTCATTAACTGCCCTTTTGTCTCTTTGAAGATACCTGTCTATGTTCCA +GTCGAATACGAAATTCTAGTAATTCAAGTTTTTCAACTTACCACCCACATTCCTGGATTC +TGACAGACAGTGGGGCTGAGACTATTGTGGGGATAAAGTTGCCTATATAACAAGTTTTCT +CTGGTTTGAAAACTTAAGTTCAGCACATTTAGAAATAGCCTGGAATCTTGAAAAATGAGC +CCTGTTTTTCATAGCATCCCTGATACCTTCCTTTCTTAGCCTATTCACACATAATTGTAT +CTTTTACAACTAAAACCTATTCTATTAAAATGAATTGCTTATAGTTATTATTATACTTAA +AACATAACTGTTTTGAGAAAGTTGAAAATATGTGTTTGGAACCTCACTGGGCTGTTCATA +AGCTATTGTCTTAATTGTAAAAGCAACAAATTCAGTGCATCTGTAAGAATGTGATTTTAA +GTTAATGAAACTAGTTTTCATGTGTTGTTTATTAAAGTTATTACATTATGGTCACATCTC +AAACATTCTCTGTAATTATTTGATGGCTAAATGTGGCTGTCCTTTTAAGAGGAAAATGAC +ATTATTGATCCATTGTTACTCCCCACCCACAATTTACTTTAATTGTCTTTTCCTCTTATG +GGCCATGAGCTTCCCACTGGCCTCTCAATTTCCTCATGTAACCAAAGATATCTCTCAGAA +GCTGGTAACCAGGGTGGTGAGTACTTGGTGTTTTCTGGAGCTATGAACTGCTAACTGGAC +TCATTCATTCAGTCAGTCCATCAATGAGTAAATGTATTTATGCACTATTGAACACTTACA +CAGATTCTACACCACATAATTTTATTTTCTGTATGAATAGATGGCATAACTCCTGTTTTC +AGAGAGCTCAAAATTTTGTGAGAGGACCTGCAAAGGAGCAAGCAATTAACATAAAGAGTA +TTCGAAGTTAGCGTAACAGAGCCCAGAGAGGTAACAGAAGGTGTCCCAAGGGAAGACAGA +ATAAGAGCTCTCAGAAAGGAAGAGCTAAGGGGAGGATGTTCAGGCAGATAATGCCGCATT +TGCAGGCAGTTGCAGAGAGAACCTTGCTCCAGTAGTTCCATGAGCCTGGACGGGAGGAGA +GGAGAGAGCGGGAGAGGAAGACAGGGCAAGGAAGCCGTTGGGGAAGGCTTTGGAAGCCAT +TCATTTGGCATTTACCCTGCAGAAACTAGAGAGCAAATGAAGGATTTAATCAAGAGAATG +ACTTCTGTCCAATTAGTATCAAATTCTAACTGAATTAATCAGCCATACTTTATGCCCTTC +CTATACCTGTCAAAATGTCCAAATTGTTATTTTTTTTTATTGTCCAAACTGAGTTGGCTT +CCATTTCTGACAGATTTGACTTTGAAATGTTTTTGCTTATCTGACAATATGGAGATTTTT +CTTTCTGGTCTGAATCTCTGACTGCTATTTTCCTTCCTCAACTACCTGCTGGAAATCTTT +TATCATGCTAAATTAGAAAGGTAAATATGCTCCAAAAAATAATGGTAAACAATATTAAAA +AAGAGATTATGTGCTATTTATATGATATTAACTACCTGCCTTTATCGTCATTTGGACTGA +ATGAACCAGTTTAGAAACCAGTTTAAATCATAATTCATAACATTCAAAATAGAAAAAAAT +CTTAGGAGGTCCTCGTGGAAACATCACTGAAATATATTTTTGTTAAAAGTATCCCAAGAC +TGTAGAACAGCTAGATCTAGAGAAATATTTGAGAAAAGTAGGCCTTTTGATATGTGTCCT +TCCAAATATTTATTTTGTATTTTAAGTATAGACTGGAAAATAAAAAGAATGCCTTTCATC +TCTTTAATATTTTGCCTCAACTTCGCAGTCAGCTCTTTGGAACTAGAGGATTTACTTCTT +TTTTCTTTAAGATAATGAAAAGACCAAAACCTATCAATATGGTCATTTTGTATATCTTAA +TGAATAAACTGAAATGCTACACAGCGGCTCCAGTCACCTGATTTGGAATTGATTGTGAAT +ATATCCAAAAATACGCAGCCAATTTGATCCCTGCATGTAGATGGGGGTCTATGGATGGGC +ACTGTGTGGGGGGATTAGAACCCTCTTTGCATGGACTCCAGCTGAGAGAACCCTTCCACA +TGTTAGCCAGAGACCCAGAGTAGGGGTAAGCAAATGTCCTGCAGAGGCATGGCAGAGAGC +AAAATCACAGATGCAGCTTGCTAGAATTTCCCACAATCAAAATATCTTATTCTTCCAATG +ACCTCAGCAATGAAAAAGTATCCTACATTTCCACATTAATAATCCAGTTTTCCTTTTCAT +GTTTCTCCTTTGTTTCAGGAGCCTCAGGCCTAGGGTAACCCAGAAAGCCTTCTTTCCTCC +AAGGTTATTTTATTATTTAGGACATCATCGGTGATAATAGGAGCTCCTTTCCCATTTTAA +AATTTTGGACATGTAGGATTAAAACATTATATGAAAGACACTCTAGGGTTAATCACTAAA +CCTACAAATGGCATTGGCAGTCTTGCCCTGTGTAGATAGGATCATCTATGTTTGGGTTTA +TGGGATGAATATCATTAAACTGAATGCTCTTACTCGGATTATTTTTTTTTATTTAATGTT +TTGCCCAAGGAAAGTCTTATTAAGTGTTGTAATGGCTCTAAGAGTTGTTGGTTTTTTTTT +TTCATTTTATTAGTGGTTGAGGAAAAAAAAAAACCCATGATATTAGTAAAACTAATTGTT +ACTACATTAAAATAATGCAGGTTTATCTCTGAATTAAAGCGTGTTACTTTATCTACTCAG +ACAAGTGACCCCAAAAAACCCACCTCTATAATAGACTCCTTAAATTGCATTTTATTAAAA +AAAATAAAAGAAGTTGGAGTATAAACTTAGATCCTTTTTAGTGGCATGCATAAGCATAGT +TTATAATAACAGCAAACACTCATGGCAATTTGAACATGCCAGCATTCTTCCATGTATTAA +TTTCCTCACAAGATACCTGTTTTAAGGTGGCTTCTATTATATCCTGATTTTCCAAATGAG +AAAACTGAGGCATGGGAATTAAATAACTCACTTGAGTTCATAAACAAGGAAGTGGCAGAG +CAGGATTTGAACTCAGGGTCCATCTCCACAGGGTACAATTGGCCACTTCACTGAATGCCT +TTGACAAGGGAGAGAGTTCAGATTCCACGCAGTCAGCCCACTTTGGCAGGCGCAATCTTG +AGGAACAGACTTTGGTCTGACAGTGTAGCCATCTTCATACAAAGAGAATAAAGTCTTTTT +GTTGTTGTTGCTGTTGTTGTTATTATTTGTTTTAATCCTTGGAGAAAGGAAAAAAAAGTA +AGATTAGAGAGAATGCATGTGTTACCTGAAAAATCCAAAGGGAAAATGGAAAATAAAGTA +AGGCAATAATTTAAAGGAGTCCTAAAAATTAATCAGCTCTCTAATGGGGATGACCAAAAT +TTGATTGATAATAGAGGCAGGAAAGTAAATTATTAGAAAATGCTGGCTTAAGAAATACAC +TGTAAAAATGGTTGGGTTTAAAAATCATAAAACCATTATGATTGTAAGTACTTTATTATT +CCAATTTTCTTTTCTATTTTTGTGCTATGTTTTTTTCCAGTATATTTTTATTCAATCAAA +GCTCCAAAGCAGTTTGTAATGTAAAACTTCAAACTGTTTCCATCTGCATTACTGGCTCTT +TCACACTAAAGTGCCCACTAGATCAAGGTAGCAAGTGTGTTCATTGGAAAAAGCTCGGTG +CTATAAATAACAGGAATAAATTGACAAGGTTTCCTGAAAGGATCACCAGTGTTAGGAAGC +ATGTGTAAGGCATGAAATGTAACACAGCTTAAATTTACTAGCCCATATAATCATCAAAAT +TAGACTTAGGAAATATCTTTAAAATCATTTAGTTTAACTCTGAACTTATTATTTTGGATA +ATTTTCATTGATATAAATCCAGAACCTATTAGAACTCATTTTTTAGGTTGTTTCCCTCAA +GCTCTTCTCTTTAATTTTCCTTCCTAAAATATTATTCTGCTGGGAATGAATAATTTACAT +TTGCTACTTCTGTTTTACCCTCATTATATGTTCCTCCCCCGCAAGATAAAATCTCCATCT +TACTATTTGCTTTGTTCAAATACCAGTCAACTATTTCTCTCTAGTATGTGAGATGTGTGT +GACGCAGATGACATATATCTTTCGCAGACTGATTTCTTTTGATTAGGTCTCTACTTTTCT +TCTTTAAATAATTATTAAAAATCTTTATAGTTTTCTGTATATCTTGGGTCATAAATAGAT +TTCAGCATTCTGTTATTTTAATTATAATCCTACTGATTCAGAGTCCAGAATAAGTCAGAA +ACTTGCTAAAAATACTGAGCTAGGTGAGAGGGACACCATAGAGCCGAGATAGTAAAAATG +GTTCATTCTCTTCATTTGAATGCAAATTATAGGTTATCTAAAATATGACTCTGGAATGCA +CAAGAAGACACACACTGAAAATTAAAATTTTGGCCATGTCTCTTCATGATAGTAAACAGT +GATTGAAAAGTGAAAATACTCATTTGATCCTCTCACGATACTAGTGTTCTGTGATAACAT +CATATAAAGATGAATGAGCTTTTTGATCATCCAGCTTTCCAGATATCCTACTTGAACTGA +CCTTGAGAAGAGTGATTTTTGCCAATACAAACTCTAAAGAGGCTTTGGCGAATGGAGAAA +AGATGATCCTCTTCTCGCTGGCTACTTTCTGGGGCTGCTTTGGGACTTCTTTTCACACTC +ACCACAGAAACAAAATGTAGGGACAATGGGATCCCCATTTCACTCTGATGTTCTACAGCA +GGCAGAGGGTCTACCCTGCCACCAACAATAGCTGTAGTCATCACAACAGCCTTCATAGAA +TGATATTCAGTTGTAGCATCAGCAATAAGACAAAAGAAAGTCCTGGAGTCACGTGCCCGT +AGAAGCACCTGTCTCTGGCTTTTGGTCAGGGTCTTCCACAGCAGTCACTACCATCATTAC +AAACCATGTGTTTCAAGAACACATTACTTTTGAGAATGCCAGGGCTGAGTTACTCCTGTT +TGACATTCTCCCATCTAGCTTCTCTAGGCTCCAGAATAAGAGCATCCCCACCATTATTAC +CAAATAATACTATTGTCAAGATGATGATGTTTAGAGATCCCAAGAAATCAGTCAGGTGAG +TACTCCCCTTCTACACCACACACGTACCGCTCTGGTTTCTTCTGTTGGCATTTTCTGCTG +CTTCTGTTGCCTGACAAACCTGATAAATGAAAGCCACTGATTCAAAGCCAATATTTTACA +CAGAGAAAGGAGATTCCAGCTGGGACTACTCACCAAGGTTAGTTCATAGGCAAGAGAAAA +AAGCAAGGAAAAGGATCTAGAGATCTTGGTGAACTAAAGCTGCAGCCCAGGTAAGTACAT +CTGAAGAGTTGTACAGTTATGATGGATCAGAGCCCAGAGAAGTAGGAGTGCTGTTGATAT +TACTCGTTCTTTAATTCATTCATTTTTAAAAATTATTTGTTCTTTAATTCATTGATCCAG +CAAATGTTTACCAGGTCCTGGGTCCTGTGCCAGGTACTATACTAAGTACTGGAGATATGA +AAATGAACAAGGTAGACATAATCCCTGCCTTCATGTAATGGATAGTCTAGTAGGGAATAA +AGATGTTACACAAACATAAAAATGATTATTTAGTCACAACTATGATAAATGCTTTGTAAG +CATCTAAGATTTTCTTAAAATACCAGACAACTTCCAGTAGCCAATTTGATAACAATAAGG +GAATTTGTTAACATCAGGTGGAAAATGCTGGCAGTTAAAACTTTTTGTCTGCATGTTTCA +CAGGATTTAAAAAAAAAAAGCTCTTCAGAAGATTTTAAACATTATAATTAATATTTTACT +TTCAAGCCTGTTGTTGATTTTAGAAGATAAATTTGCTATTTAAAAAGATAACTAGGGCCA +GGAGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCAGATCACG +AGGCCAGGAGATCGAGACCATCCTGGCTAACACAGTGAAACCCCGTCTCTACTAAAAATA +CAAAAAATTAGCCGGGCGTGGTGGCGGGTGCCTGTAGTCCCAGCTACTCGGGAGGCTGAG +GCGGGAGAATGGCGTGAACCCGGGAGGCGGAGCTTGCAGTGAGCTGAGATCGCACCACTG +CACTCCAGCCTGGGCGACAGAGTGAGACTCCGTCTCAAAAAACAAAACAAAACAAAAAAA +ACGATAACAACTATATTATAAGACATCATTTGTGAATTCCACATTCTCATATGTAAGGTA +AACACAAAGTTTGTATGAGGTTCTCTGTCCGGGCAATGTTAACTATTGAAAAATTACATT +CTAGGAGTTTACTCTGATTGAGGAAAATAAGATACACCTTAAAATAACCACAAAACAAGA +ATATGAGCTAAGGCCCTTGGCAGTTAATGTACCTAAGTGCTGTTTACATATTTTGAAGCT +AAACGTTACAAAGACTTTTTCTGATTTATATATTTACATTAAAAGTCTTTTACATTAAAA +GTCTTATAAAGGTATTTTTCAAAGCCGTTACACATGTAGTAACACAATTAGTAAATCACA +TGAAATCTGAATGACTTTAGAAAGACAGGGACACATGAGTGGAGACTGGGAGGACGACTA +GGTTCACTACTTAGGGAGGCCAGAATGGAGTCTTTTGTGGGTAATGAGGGCAGTTCAGGG +AGAAGAGGGCAGTAGAAAAGGTATTTTGTCACAAAAGATTAAAATGTGTCAGGGAGACAA +GCATAGAGATTTATTTTATTGTTATAAAACAGAATATAAAAGTAGGTTGGGGTCTAACTA +TTGTGGACTTCGAGTGATCAACGAAGGAGTTTATATTTTTTCTGATATTTTATGCCATTG +AAGGTTTTAGGGCAAGGGATTGCCATGATCAAAGTAGAAGAATCAGTCTGGCTGCAGCCC +ACATAATCATGGTGACATAATAAATTGTAATGACTCAAAGCAGTAGCTGGAAATTGAGAA +AGAAATACATGAATTAGAAGGTGTTGAAAATCGCTTATGTTGACTTGAGACAATGGTATT +CATCTTTTCTGTGAGTGTATTTGTCTTCTGTTTAGAAAAAGACAAAGCAAATGAAAAACA +ATCTCTTCATTCACCTCCAGAAAGGGGTTGGGAAAGACAAATAAAGGGTTATTCATAATC +TGTTGGTTACCCTCTGTTGGTAGTGGACAGAGATGAAACACTTTTTCGCTGGTGCACAAC +TTTATTCTTAGCCGTGAACATCTGTAATTAGATGAACCACCATAGTGATGACTGAATTGA +GAAATCAGCCCATTAGAGGATCTGGTGGTAAAGGAATGGAAATCATTATCTAGCACAAAT +AATGCAAAGTTGGTCACTTACTCATGTGTGAGTTACTGTGCAAACAATTCTGATAAAAGA +GGGGGGAATGCTATGGAATCAATATTGTCTTTATTGTGAAGAGGAATGAGAATGAACAAA +ACCCTGAAGCTTTGAAATGTGGTAAATCTCAATACATTTACTCTGAGAATGTGACTGCAT +CCCCACAGTTCTTCAGAGAAAGGATGTGTGGGTGTGAGAGTGAGTGGGTGTGTGGGAAAA +GCTAATAACAGTTCTAGGTTAGCTTGCTTCCTTCCTTCCTTCCTTCCTTCCTTCCTTCCT +TCCTTCCTTCCTTCCTTCTTTCCTTCCTTCCTTTTTTTCTTTTTTTTTCCTTTACAAAGC +CTTTACAATAGCAGTTTTACACCTTTGAGGCCTTTGCTAATTTTTGAGACATTTTATACT +CTTTCTATTTAGGCATTAATCAGGAAATTGGTCTTTTCAAAGTGTGAATCATGAATAGTG +AATATGAAACATTTTAAGAATGTAGTAGGAAAGATATTAGCACTTTGGGGAGGTTGCTTA +GTGGAGTGAGGGAGCTAATGAATACTCTGAGTTATCTAGCTCTTTTCATCTATGCTAATT +AGCCTTAACAAGGCAAGTTAAAATAATTTCTTTCCTAGGCTTGTACAGTGTAACTTCCCA +CTTAGCATTTCTTGTCTCCTTACAAGCCTTATAACCTGAGGCAATCCCAGATATTCCCTT +TGGGAAAGAAGTATTTGAGAGTTATGCTCACGGCACTTGCCTTTATTAATTTTATGAAAA +AAATCCATTTTAACATTCATTTTCATATTTGAGTACCCAAGAATTTGAGGTTTGTATGTA +ACCATTGTTGGGATTTTGTTAAAAGAAATGTTATAGTACAATCCATCATGACCCAAACAC +ATCTTGATGAAATGTTCTGAAGTTTCCTATCTTTAAAAAAAATGTATTATGCTATTTCTC +TTATGGTTCTTATCATAGTTTGTTGAAACATTCCAAGGAATTATAGTTCTAAGCTACCTT +GTATTTGACAGATGTCAGTAGATGACAGGAGATTAATCTATAGTCCTCTCTCTCTCTTGT +TATTTGATTAAACAGATCCATGCCACCATCTTTCCTTCTTGCCTGTAGAATACACACACA +CACGCCCACAAACACACACACGCCCTTCTATTTTTCAGAATTCTTAGCCACACCCCCTCC +CCTCACCACCACCGTTTTTCCACCCTGGTGCACATTTTTGTAGCCATTGCTCTTTAAGGT +GACAGTGAGAGAGACTTCTTATCGATCATCTGACCTCCCACACAATTTGTTGGAGGTTGA +CACACTCCCTGCCATTTTTGCTTTGTGGAGGCTGAAAGGCCCATTCATTACAGGGATGGC +TTTATTAAAGAAGCAACCCCCAAATTCAAGTGGATTAAGCCATCTGGCTACAGAGTGAAA +TCCTTCACAATCTTATGACAATCTATGTCCCCCATCCTTCCCTATGAAGTTAAAAGACTA +TATATAGATTTTCCTTTCATTTTTTATAAATGCTCCTTGGATTTTTCTATCATACTGCCC +TCTATTCTCTGAGGATAATTCTTAGCCATAGCTCCTTGTGCTTATTTCTTTATAAATTGG +CAGTTTTTAAAATGAAAATCATTTTGCATCTATTTAGATGATCTCAACATTTTCTCTGTT +TACATTAGTTTAGGGCACCTTTGAGTCATTTCCTTTTCATTTCTTTTCCATTTAGCCTGG +ATGTTTGGCCCCATCTGTGGTTAGTGAGAACTGAGGCAGAAGCTGAGTCCACCCTTCAGT +CACTCTGTACAGCTGTCCTTGGAAATTCCAGCCTTGAGGAAACATACATTCACACATAGC +TTGTTTCCCCCGAAATAAAGGTTTTGATCAAATATGCAGGAAGGATGTTTTCTGTGACTT +GGGTACAGTGGGAAGTTTTGCATATTGGCCTCTCTCACCTGCTGTTGAGCACCTTGGCTG +TGTCTTTGTTCACCTCCCCCCGTCAGTGTTTTGCACAGCAGACACTAACAAGTATTTATT +GAATGAATGAATGTGCAGATGAATGAAAGTAGCATGAAGGACTAATGCTGGTGTGGTGAT +TGTGTCTTGTTTTCTCATTGTTCCAATATTCTATCTCAGTTTCCTCTCTCAGGAGAATGC +CTCTTTGAAGTCCCTGAAGAATTACAGAATAGTAGATGCTGATAAAAATTTATACCAAAT +CAGTAGGAGGATAAGGAAAGGAATGTAGAAGTATCTACAACTATACTTTGGTAAACTGTT +ACAAATTCACCCCTCCAGGCTCTATAAATTACTTTGCCAGAAAAAAAAAAAGGATTTTCT +TTCATGACAATTCAAATACAGCACTTCTCCTTCCCTGATTTTAAGAGTTTGACAATGAAT +TAAAATGAGAGTCTGGAGGTAAGAGAACTTGCTGAAAGGGAGTCAACTAATAGTCAACTA +ACTATGATTAACAGAATATAAGCACTGAAAATTCTCCATTGTGAGTTAAGATTTGCAGGC +CTGCAAGCCTAGTGACATAAATGTCATATGCAGATTCTAAAAAGCAATGAGTTCTATCTG +TTAGGTGATTTAATTATGTTGACCCTTAGTTATTTTGAAATCACTTGTTTACAACTGGCT +CTAAATCAGCTTTCTGTTAAATTTTCAGTATAAGAAATTGAAATTATAAGAATTATGGGT +TTATACATGTAAGTTGTTTTAACATATTCAGTCATGTTCCTCTTTGGTGAGAAGTAGAAG +AAATTATTTGTTTAAGAAATATATAGGAAAATAAAGCAGAGCTATGAATGCATAGCAAAG +ATGGGAGTACTCTCTCTGGTGGTCTGGTTGGCCTCCTACCAGGAGGTGAGTCTCTTTAAT +TCAATATCCAGTAATAATCAATGTATTTGAAAAGCACATCTGTACATAATGGACAAATTG +AAAATGCTTCCATCTTCCTGCTCCTTGTCTCAGAAAAAAAGTCATCTTTTCAATCTTTGT +GCTTTCTTTGCATTTTTTGGGCACAATTCTAATTGCACGCTAGTCACATTTTGGAGTCAT +TTTTAATTGCTTATCTTCTTCTTTTTCCTGGAATGTGAAATCCTATGTCTCATTCATCTG +TTTTCTCCTATCAATGTCTAATATGTGGTAATATGAAATTGGGACCACTAAGAAGTATCA +CTTGAATAGTGAATATGGGAGGGGAAATGCTTATATGAGGAAAATGTGCTGGACACCCGT +ATTAGTCCATTCTTGCAGGGCTATAAAGAAATACCTGAAACTGGGTAATTTATAAAGAAA +ATAGATTTAATTGGCTCATGGTTCTGCGGGCTGTACAGGAAGCAAGGCTGGGGAGGCCTA +AGGAAACTTTTAACCATGGCAGAAAGTGATTCAGGCATGTCTTACATGGATGAGGCAGGA +GGAAGACAGTGAAGGGGAAGGTGCTACATTCTGTTTAGCAACCAGATGTCATGAGAAGTC +ACCATCATGAAAGCAGCAAGGGGGAAATAGGTCCCCATGATCTAACTACCTCTCACCTCC +TCTAACATTGGGGATTACAATTTGACATGAGATTTGGGTAGGGACACAAATCCAAACCTT +AGCAACATTGTTTTTTTTTTTTTTTAAGTTTAGACCTGGTGTTACAACTACATAACCTGG +ATCAAGTCATTTAACTCTCTAAGGTGAGAGTTTCCTATTCATAGGAAGAGGAGAATAGCC +ACCAAGAAGAAGCAAAAGAAAGATTATGTGTGGACTGCTTTCAGACCTGTAAAGAGCTGT +TCAGTTTATGTTATTATGTTAGCATTTCAGCCAGTGGGAGTGCTCTTTGGGTCTCTCTCC +ACTCCCTGAACATGTTCAGTGAAAACTATTGGTTTATCTAAAGTTTTAAGCTGTGGGTCT +CATGTACAGATTTCTTTCACTTCATGTCAACATTGATTTCCTTCCCTCATAAATTCAAAG +CACTAAAGGGTCAGAGTTAAAGGTGTATGATTGCATCTTGGAAACTACAGTCTCACTATA +GTCACAACACATTGTACTACAATGTACAAAAAATGTCAAGAATATAATTCAGAAACTGTT +CCTCAGCTACTTTAATTCTTCAGTTGTGCATTGGGAGACGTGTTAAAATGTCCATACTGA +GCCTTCACCTTTGTCATTTGTAAAAAGGGATGGCAAGACCCACCTATATGGTTGTTATAC +AGATAAATGAGATAATACATCTTAAACACCTTGTACAATGCCTGGTCATCATAAGACTTG +TAATGAATAGTAGCAATGTTGACCATTATTCAAGGAAGAGAGAGTTTAGTATGGACTGGA +AGAATACTGGGGAGCTAATGTGTGTGTTAGATTTGAGTGCAGGAGATGAATTTGCATAGA +GGTAAATCATGAAGAAAGGCTCTGAGGTGACTGAGCTAATGCAAGAATCAATATCAACCC +AGTTGTTCAAACTGAAACCTGGGTATCAACTGTAGCTTGTCCCGTACCCTCATGCTCATT +CCTAAAATATTCAATTCACTACCAACGTCTATCAATTCTAACTTCTTTCAGATCTACCTA +ATCCTCTCAAATTCCACTGCACTTTTCCATTCCCAGTACCTCTCTCCAGCCAGGATCCCT +CCCACTACTGTCAGTCCCCAGGGTGTCCACCATACTCTTGCCCTCAGGTCTTTGAACGTG +CTGCTTTCTTAACATAGAGCAATTAGCCCCTGGCTGCCTTTCCTTCCCCAGTTGAGCACA +CAGCAAGCACACATACATTAACTCCTAGACTCCTTTCCTCCAGTAGGTCTTTATCATAAC +ATTGCATTTCCTGTTTATTTCTCTCTGTCCTTCACTAGAATGAAAAAACAAAAAGCACTC +TGCTAACCATCAAATAAGAGCCCACTTTCCACAAATTCTCAGCACACACCAGACAGTCTT +CTTGCATTCAAACTCTGCCCTTCTTTCCCATACTGTGGATAAATTGTCCCCATTCCAAGA +CCAACCTTCCTTCACATACTCAATCCCATCTCTCTTACCAAAGTGAGGACATTACTGCAG +ATATTCTTCTCCTTTTCTCCTACATTATCATTTCTCTTTTATAACATCATTTCTGCAGAT +ATGTAAAAATACATCCCATCTTCAAAAAGAAAAACAAAAATCTGACTGTACTTCATATCC +CCTTCTAGACATTGCCACATTTCTCTACTTCTGTTTACAACAAAACTCCTGGAAAGATTT +GTCTATACTGGCTTTCTCTACTTCTTTTACTTCCATTCCTTTCCTAACCACTCTAAACAT +GCTTGGGTCCCCACCACTGTAACAAATATAATTTGTGTCCAATAACCAGTGATCTCTGTA +TCACCGGTTCCAAGGGTGAGATCTCAGACTTCACCTTTCTGGATTGATTGACACATTGGA +CTCAGTTGGTTACTCCTCACTTCTTGAAACTGTCTTCACTGGGCTTTTTGGACTCCTGAT +CTTGGCTGTCTCTCATCATATTTTTTTTTTTTTTTGGCTTTTCTTTACTGGTTTCCCCTT +ATCCCCCAACCTCTTAAGGTACACTGTGTTTCCTCTTCTCTATCTGTACTTTCTAACAAA +CCAGTCTCATGGCTTTAAGTGTGAACTATATGTTGATAAGCCCCAGATAACTTAATCTCA +GACCTCACTACTGAACTCCAGAGTTACTACCTATTTCACATCACCAAGTTCCTATTGAGC +ATTTCATGGTGAACTTATCTAAGATGAAATGTCCAATTCCCACCTCCTTCCCAAAACCAT +TCTAGACAACTCCAGTTCAATGCAACTCCATTCTGCCAATTGCTTAGGCCTAAAATCTTG +TAGTTGTCTATCAGTAGTCTTCATCACATGAAAAACCTTGGCTTCTTTTCTTTATCACAT +CCAATTTATCAACAGATATATCTAGGAGCCAACCCTCCAAGCCATTGTCATCTCCCATGT +GGATAACTGACGTAATCTATCTGGTCTGTTTCCACCCTTACTCCCTGTAATCTTTTATCA +AGATGGCATTCAGTACAAATTTTTTTTAATGTAAGGCATGCCATGTCACTCCTCTGTTAA +AACACTTTCCAGTGACTCAATATCTCTAGTAAATAAAAGTCAATCTATTTTTAGTGACCC +AGCTACCTCCCTGACTTCATGTCCTACGAATCTCCTCCTTGTTAGTTTACAAATCCTGTA +GGACTCTCTTTTGGCTTCTACTACATCTTCAAGGATGCCTTCACTGAAGGGCCTTTGCAC +TTGCTATTCTCTCTGGCTGGAATTTTCTTACTTCCCAAATCTACATGACTCACTCCCATT +CTCTCATTTTCCTCAATTCTCTGCTCATTTGGCACCTTTTCAGTGAAATCTTACTTTATC +ACCTAATTAAAATAGTATCCTCATTTCTACCCTTGGCATTTCCAGTTATTTACCCTGCTT +TATTGTTTTTCCCCGTAACAGTTACTGCTTTCCGATATACAATGTTAGTTTGTTTGTTTG +TTGGCTATTATTATCCACATGAAGGCAGCTTTGTGATAACAGGGATTCTATAGGTTCCCC +CTTCCCATCATTTGTCTTTATCCCCAATACCTAGAATAACATCTGATACATGGAATGTGC +TTAAGAAAACATTTGTTAATTGAATAAATGAATGAATGTTCCTCTTAATTGATTATGGGA +GACTAGGATATCAGTCATTTCTTCTAGCTCTGCAGCTAAATATACTAGTGTAGAGTAAGA +TTCTTATGGTTGTAAACTTGGCATGTTACATTTTATATCTTTAGACTACTTAGCAGATTC +CATGGTTGAGTTACTTTTAGAGATTTTCTTTCTTTTCACGTTCAGACTTCTGCCTTTAAA +TATCATAAACTTAAATGAACACATAGACATCAGCAGCTTTAAACAGTTCTGTACGGATGC +CCTCACAATAGTGGTCTAAGCAATTGTTTTGCTTTTAGCATAGCTGGCTCAGTAATTTCT +ATTTATGTTCCAAATGCCATTGAAAAGCCACTGAATATTACTCAAAGTATGCCAATATGA +AAAATATCATCAACTGCCATTTTATTTCAAGCTGGGCTTCTGCACAGCAAACTGTTCCAA +AGTTGGTGAAAACCAAAAATCCAAGTCACCTTAAACAGAAAGACAGATGTAAAACAGTGA +GTAACTTTTTAAAACAGAAAACAAACTTAATGTGCTGTATATTCTTTTATTATTTTCTTA +GCATTTTTTTGACCTGTTATTTGTATTGAGTTTTTTCTGTTATAGTGAAAACTGTTTTAT +TATTTCCACAGATAGTTTAGTAAGATATGAAAATCTCATTGTAGACTGCCATGGTTGGCT +TATTTCTTCACTTATTCTCATGATGTCAAAGTTCAGGCTTTGGAATCAGGCTTGTTCATT +TGGAATCTAAGCTCTTTGAATTTTCATCTCAGTAACATCAGACAAATTGCTCAACATCTC +TAAGACACAGTTTTCTCATGTTTGAAATGGGAATAATAAGGTTGTCATGATGATAGAAAT +AAACAATTCCTATATAACACTCAATACATATTTACCAGTATTTCTGATGTTATTAATGGG +TTCTCTTATGCTGTAGGAAGAGCTGTTTACCAGTAGTTCATAATTTGGAGCTGGATATAT +TATCTCCAAGATATAAACTTTTTGTTCACTTTCTAAACAAAACCCATTAATCTGAATATA +TGGATTCCCGCCCCCGCCCCCGCCCCCGCCCCCCCACCCCCAACCCGCCAAAGTGCAGTG +CTTGCTCCTTTCTCTGAGTCATGGTCTGACATATTTCTTTGAACTTAAAAATTAAGTTTT +TCATTTATATTACATTTGCTGGAAAGTTTGTTTTGTTTGCATAATATAATATTTATTTTA +AGAGAAGACACTTATATTGTGAAAGCACTCTCTCCAGAACAATACACAACATATAGGATG +ATTCTGATGATAAAGGAATTAGACTACACATCAAGTAAGTTCATTTAAAATAATGAAGAA +ATTATAAGCAACAGAAAGTGTTCTACATATTCAACCAAAAGGATTTAAAAAGCAGATTGC +TTACCACAAAAAGTAGAAAACAATAGACACAAATCTAAAATTAAGATAATTTAAATAGTT +ACAATAACTTTGTCTATAAAGATACAGATTGTAATTTTGTACTCCAGGTAGCATAAATCA +ATCCAAACTATATTTTAATTGATATTGTAAGAATTTTTTTTTATTATTATACTCTAAGTT +TTAGGGTACATGTGCACAATGTGCAGGTTAGTTACATACGTATACATGTGCCATGCTGCT +GTGCTGCACCCATTAACTCGTCATTTAGGATATTGTAAGAATTATAATCACACAAACCAG +TTAGAAATCAAGTCTAACCTAAGCAAATTTAACCTCTTCAGGCCTTTATTACTATTGTTT +GTAACCTCCATGTTTTCCTTTACCATTTTCTTCCATATTCAGCTTATAAATAATTAATTC +CCTATACTCAGAAGTTGTATTTAAAACAAAACAACAAAAACACATTAATAACTAGCAGAC +ATCAAAGATTTTAATAACCCAGACCAGCGAAGAATAAGAATCCAAAATAGCTTCGTTACA +ATAACAAACTGATATATTCTATTGTAACCTTTAGTTTGCTGTAGATGGATACTTCATTAA +AAATAGATATTAGAGGTAAAGTTATGTATACAACACAGAGAAATGTAGTTGACTTTTCCA +AATCTGGTAAAATGGATGTTTCCCCATCTTTAGGTGAAAAAAAAATTCTACTAATCAGAG +ACAAGAATATAAGATATAGAGCTTTGCAGAATAACACTCCAATCATGTTTGCTTCATGAA +TATATATTAGTGACTTCAAAATCTAGGGCATACACTGTCTTTTAAATGCATTTTAAAAAA +TGACATTAATGAAAAGAAGGAATTATGGGGAGGTAAGACCTTGTTCTGTCAAGTTTAGTA +CCTGTTCTAAAAACAATGATTCAGAGTTTTAAGCTAAAACTGTCTCTTCTAGTTAAAATA +CCCTTCTGACCAAATAGTGATGCAGAAAACTTTTAAAAGTCAAATGGAAATCAGCTTGGT +AAAACATTCTTGGTGTTCTTAAGTGACTCTCCAACAAATATTTATCGAGCACCTCGTTGT +GTCAATACCATGCTTTTGCAAATGGCTCAGTTAGTTATCATCAATAATAGTATTGTCTAG +ATTTTGAATAATAATAATATTACTAATAATACTACTAATAATATTCTTAAAGGGTCTAAA +AGAACTTTCCTCAGTCTCTTTCTCGAATAATGTTTTTTCCATGTGGCAAAATGTTTCCTT +CCCTGAGCTTTTTTTCGGGAACACAGATAATCATCATTGTTCCTTCCTTGAGTTTATAAA +CTAATGATTCTCTCCATTTGCTCCACCACTATTTAGCTCTCTGCTGGGCTAATCTAAGCA +TCAGAATCCTTGGTGGTTAATAAATGAGCATCTTAGAAAGAATTCCACTGGGAACATGGT +ATTCAAATCAGCCCTCCAGGGCATTTTGTTGCAGTGAATTCCCACAGGTACGTGGCGCAA +GATGGGAACTTCTCTTGGGAAGGTTATTTATGTGCTCAGCCTGTCTATACAGAATTCAGG +TATAGAATACCTGAAAACACTCAGAAGCAGCCGTCAACCCCCAGAAGGAACCATTTCCCC +ATGTATACAGTTGAGCAAGTGAAAGCCATTCTGTATGTAAGAAAAGTTGTCAAGGGGCAA +TATTGAGGTTTAATAGTGCTCTCTAAGTCACTTGAAAACCAAATCTTAAAAATGATGTAA +TGTATACATTTGGCCTTCATTAGTGTTGTATTAAGCAGGTAGGCATTATCTTGGTCTAAC +CATTAAGTACAAATGCTTAAGCAGCTTAAAGCCCTGAAGTCGGAAGCACTTAGAAGCTCT +GGTAAAATTGTCCATAATACAAACTAATCTAAAGCATCATAAATACTTAAAGATTGCTTA +GCATATCTTTACTGTCATTGTTTTGCAAGCAGCTTACTTTCTCTAGGATAATAAAGATGC +AAAGATCAATAATATACTATTTCTTAGTAAAGGAATCAAATGCATATCTATTTTTTCCTC +TCTATGAAGGCTGTCGATTTTTTCTTCTTGTTTTTGAACAGTATCAGGCCTTGCTAGATG +GCATGAATTACTCAGAAGCTTACAGACATCAAGGTAGGGGGGTCCTGAAAGGTGTGGCAG +GGGTCGCTGAGCAGTGAGAATAGCCGGGAAGTGAGTGCTGAGTGATGCAGTGGAGAATGT +ATAGAACTGGAAGGGAGAGCCTGGAATCAGACGTTAGGTTGTTTGAATCCTGATAGAAGA +ATGTATTGGCTTGTGAATTAAGGCAAATTATTATAAACTACTGAAGTTATTTAAATCTCC +CCTCTGAGAATTCTTAAGGGAATAGCATGAGATAGGCCTTTGAAAGTGCAAAATGTAAAG +CAACATAGTTATTGTTGTTGTCGTTGTTATTTGTAGGGAAGGGGTTAGTTTGGTTTGGTT +TTTTAAATAGAAGGAACAGGGATCTGAAACAGCAGCCATGCTTGCTGTCTTTCCCAGCTT +CTTTTCCAGTCTGCCACAGAATGCCTCATGCGGTGACTTATACCTAGTAGGTGCTGTCTG +AATATTTAAGGAATGAATGAAGCTTTTTTCTCACAGTTCTGAACTTTGCAATGTGAATTA +TGTACTTCCTTATAATGATGTTATTTTTATATACGTCATCTCACCTGTTAATTCATGGGC +CTCTTGTCGAGTACATATCAGTCACAGTCATGTACCCATAGTACCCCAGTTGGTGATCCC +TGAATATGCATTAAATGAACTAAATGCATGAGATATAAACCCATCAAGCTTAATAGTTTC +ACTTTCACTTTTTAATTACTTTTTCTTTCTGACAATATCTTCTTCTCTTCTGAATTACTG +AAGTGATTTATCATGATTATCCAGTAACTTGACTAATTTGAGAATTAAAGCAAAGTTCTG +TGTCTTTGGAACTTACCATTTACTAACATCAAACATGTAGTAGCTCTTACCATGTGCCAG +TCACCCTATTAAGGAGTATATTTGCCACTGAGTTTGTATAATAACCCATTAAAGTGGGTA +TTATTATTATTCACTATTTCCAAATGAAGGAATTGGGAATTAGGGAGTAACTTTCACAAG +TCCCCAAGGGGGTAGCACTGGGATTCTAACCCAGGTAGGCTGTTTCCAGGGCCCATTCTG +GGAAAAAAAGTAACATGATGACAAGGTATTATGTGCTAAGTGTTCATGGAGAATTTTTAA +AGTGCCATCAGATTTCAGGGAAATGAAATCGCTAGGAATTTGCTATTTGAAAAGATTTGG +TGGAGTCAGTAGAACTTGAGTTTGAACTGCCTAAGAGCAGTAATAACAACTGGAAACACT +TGTATTGTACTTGACATGTGCTAAGGACCTTTGGTTAATAATTAGGTCATTTATGCCTCA +CTACAATCCTATGAATTAGGTACTATTATCATCCCTTCCTTTTACCAATGACCAAACTGA +AACACAAGCCTTAAATAACTTGCTCCAAGTCACCCAGCCAGTATAAGGGATTTGGGGAAC +AGCAGAGAGAGAACAGGTTGTCCAGATGAAGAGAATGTGTAACCATGTAGGCTTTGGAGA +GACTCGAACATATTCTGCTACCTGTGGATTTTCTCTGGGCAATGAGCAGGAAAGCACTGG +AGACAAGTTAGCTCCCACTACAGACAGATTGTAGAGGGTTTTAGATGTGTTGGCTGAAGA +ATTTATATTTGATTCTATGCGGGCATTGGAATACTGTTAAAATTATTTATCAGCATTTAT +TGTTTAGCTTTAGATTATCTATAATGGTTGCAGCACTGTGTCAGCTTAGACACTTTTGTC +TGGGAAGCCTCCTGACCACCCTTTCACCACTTTCTCCAATTCTGGAATAGATGCTTTTCT +GTGTTCCCTGAGGACCCAGAAATCTTTGTTCTTGTAGCTCTTACCATATCTTTGTGCTTC +CCTTTTGCATTAGTCAGGCTTCTCCAGGGAAACAGAACTAACAGGGCATGTGTACGTGTG +TGTATAATATAACATAAAGAGATTAATTGGCCGGGCATGGTGGCTCACACCAGTAATCCC +AGCACTTTGGGAGGCTAAGGCAGGTGGATCACCTGAGGTCAGGAGTTCAACACCAGCCTG +GCCAATATGGTGAAACCCTGTCTCTACTAAAAATACAAAAATTAGCCAGGCGTGGTGGCA +GATGCCTATAACCTCAGCTACTCGGGAGGCTGAGGCAGGAGAATGGCGTGAATCCGGGAG +GTGGAGGTTGTAGTGAGCCAAGATCGCACCACTGCACTCCAGCCTAGGTGACAGCGAGAC +TCCGTCTCAAAAAAAATAAATAAATAAAAATAAATAAATAAATATAGAGATTTATTATGA +GGAATTGGCTCATACAATTACAGAGGCTGACAAGTCCCAAGATCTGCAGTTGGCAAGCTG +TAGACCCAGGAGAGGCAATGTGTAGCTCCAGTCTGAGTCCAAAGAGCTGAGAACCAGGAG +AGCTGATGGTGTAGTTCCAGTCCAAAGACCAGCAGGCTCAAGATCCAAGAAACAATGATG +TTTCAATTAGAGTCCAAAGGCAGGGAAAAAAACCCATGTCCCAGCTTAAAGGCAGCCAGA +CAGGATGAGTTCTTTACTCAAGGAAGGGTCAGCCTTTATGTTCTATTCACTAACTGGATG +GAGCCCACCCACATTAGGGAGAGAAATCTGCTTTACTCAGTTTACCAATTCAAATGGTAA +TCTTACAAAAATACCCTCACAGACACACTCAGATTAATGTTTGAGCAAATGTCTCTGCAC +TCTGCATCCCATTCAAGGTGACATATAAAATTAACCATCACACCTTCATCATTCCACCCA +AAACCAATGGGCTCTAGTAAAAGAGAAGAAGGGCTTCTCTCTTATTTTCCTGAGAATGCC +ACAACACTTAGTACAGAGCTGGAATGCAGAAGGTGCTAAACTTAAATGTGTTAGCCTCCT +GAATATGTTCTGGACAAAATATGCTATAAATCAATTTTATCTAGTTTTGTTTTATTCTTT +GATATCTTGAGTATATATATTTGATGCTTCCTATGTACATCACAGGTAGGGATCAGACCT +TTTTGCCTTACAGCTTCTGTTCTGAATCTGATTCCTTACTAAGGAGACTCTATTAAATAC +TTGTTGATTACAGTCTTTTTTGTGTGAGGAGGAAAATAGTACATGCAGACATTTATTTAC +TAGACTTCAGTATTAGCAGTCAATCATTATCTCTTCATAGCAACATTGTCTCACTTTTCA +GGTCTACCATGCTCCCAAAAGTCACTGTCAGCTCTGACCATACCTGCTGTTCACCACTGC +TCACATATCCCACATACTTGCCTCCCCTCCTGCCTTTGCTTATGCCATACCTTCTGATTG +GAAGCTTTTCTTCCTGCATTCTTAACATGGAGAATGCCTACTCGAATTTCAAGGCTCACA +TCACTGAATCTTCACCTTCAGCCTTTCTCATGTGGAAGAATCCATTGTGTCTTCAAGCAA +GTTCCCATAACACTGGGTATCTACTTCTGCTAGAGTTTATTCAAGGAGTATTGCCTTCCT +TGCCAGTCAGTGAAATTATAGGGGTCAAAGACGAGGTCATATTCAATCTCTGTATCTTAA +GCACCTAGTACTCTACCTGACACACAGTAAGTCGTCACTAATTGTTCGATGAATAAACTA +ATGTGTACAATAAGATTATTAACAATGATATTCATGCCTAGTATTCCCTGGCCTCCTTCC +AGGCCATTTAAATTTTCTTCTTTTTTTTTTTTGTCTTATTGAAGAGATGGGATAAACAGT +CATTCTTAAAATTTTATCTTTGATGGTGAATAGAGGTCCTCCAAGAAACAGCTACTGTAA +CAGGATTAGATATGAAAGAGATTTATTGGGGAGAACTGCTGTGAGGAAAAAAGAAGAGGA +AGCTGGGGGAGGCTGGGAAATTTGTCAGATCACCATGCAGGTTTAATCCTTGTGAAGGAG +AGAGGGAAGGAATGAAGGTTAGATATGAAAAAGTGTTACACTGTGGTGCAGTTTTAAGAA +TGTTTCAAACAGCCAATCGGGAATCTTCCAAAGATCGCCCACCAGAGGGAGCTTTGTATC +TCTCAGGAAGTGGCTGCGTTAATATCCTTGCTGAACTCAGTTGTTCGCTGGGAGCAACCC +TTAGCAGTATGGACTTCCTAGTCAAACTCAGAGATGGATTTCAGAGCCCAGAAGCCAGGG +CCCTTGGTCAGTTACAATCCTTGCAGTTAGATTTCAGAGCCCACATTTTCATGGTGACCA +CAGTGGCTTGAAACCCTTGAGGCAGTAGGGAATGTCCTTTATTCCCTCTACAGTCTTGCA +TCTAAACATATTTTAAATACAAAAAGCTCTCTTTAAATAATGAAACTATAGAAAGTGCAT +GGAAACCTTAAAACCATTTGAAATTATTTAGAATCCTAGGTAAGCTTCAATTGTTAGCTA +ATTCTGACATGATAGAGAAAAATAAAATACTTAAGTGAACAAAATTAAAACACTACAGGA +AACTGTGGGCACAAATATGTTTCAAAGAAAAATCAAAGGTATCTTTTTGGCTTGGAAGTT +TCTAATGAGTAGATGTTCTACTAAGGTCATAGTTTTTTGGATCTTACAGTTTAAATTCGA +ATGGCTTCCTCAGAAGAATCACATTTGACAAATTGTTGATGCTGCATATCTTGTGAGAAA +GAACATGTAAGTCTGTTGTATAGAATAGAGCATATCTAATTTATAGGAGTTTTAAATGAC +AAGCCTTTTCTAAATTCCAAAAGGCTTTAAAAATTTGCATTCCTATAAATAAACCAGTCT +TTCTTAGAAGCAACCTTAACTCTAATAAATAAATAAAACCCAATCGTTATTTCATATAAC +ATTTTTCATGCCAGAAAGAAATGATTCAAGATAATATATGGCATAACTTATAGAAGGCAG +TGCTATTAAAAACACGTGATTGGTTTCCCTGCTCAATCCCACTCTAGTTCCCAGCCCCTG +CATTTGTCCATGAGCTCACTACTTCTCTCTGGATATTTTCTCATGGGCTTCATCTTGTTG +AAAAAGGCCTTTGCATTTCCTCCCCACCCATAGTAATCCATTACTTCCTTGAAGATACCT +TGAATTGGGAAGGACTACTCTTTTCCAAGAAGTATTTCCTAAAGAACTATTCTCTCAATT +ATCTCTTAGAGACTACAAAAGTAATATGAAGTATTGTCATTAAGTATTTGCATTCCTTTA +GCACCTATATAAGTATACTCTACACTCTACTAGGTACTCTCTTACATGTTGTCTTTTCCT +TAAGATCTTGTCTCACGTATTAAATAGAAAAGACTTCAGGGAAATAGATGATTCTTTTAT +TCCTTTAGTATTCATAAGCATGTAGTAGATCCAAAACAGAGGCTTTTATTTTGTGTTTAT +TACTTTTTAAAAATCAGACTAAGTGCTTATGATAAGAAAACCCAGGAATTGAAGGTCTTT +TATTCATTGAATTTCACTGCCTAGAGGCAGTCTCTTTTAGGCTTTTCTGTTTTTGTTCTT +ATGGTGAATTTATCTCCATAACCTCTCTTTCAATGAGGAAGTTTTAGACAATATGTACTG +ATTCCCCACTATGAAATATGAGGATCTAATAATGGGTGCAGCATTATTTTCACCAGTTTA +TCTCCTTTTTTCATTGTTTGATGATTGTTGTATTAATTTGTCTTCTGTTGATTATTTTCG +TAACTTAAAAAAAAGATTTTCTTGATGTCTTGTTCCATCAACATCAGTGAGCACTTAAAT +TCTCAACATGAGAATTTTAATGACCCTAAACTTTCTTCTACTTTCCCTTCTCCCATTCCA +CTGATCATCTCAGTTATTCTTATTTTTATGTTGTTAGGATTCTTAATAGTTACATTTTGT +GCTATAACCATAACCAGGGTTTCATGTTTGATCCATAGGTTGATTCTAAAAGTTAAAATT +CAAGTAGACTGGGGTTACTATGACTACATTGATGTTGGTCATGGATGAAATGAGTAATAG +GATTACATTTCCTTCTCTATAGAACTATGGTCTTGACCCTTCAGTCACTCAGAGAGTATT +TCCAGCACCAAAATTAAGTAGATTATTTAAAATGACCTCAAATTGCTTAAAATAATGTCA +CATTATTTTTTGGCTCATATCTACCTCATATTAATCTCTATACTTTTTTGTACAGTTTTT +TCTTTTCCTCCTTGTTTTGTTATTGACAATGGAATGTATGTTTATCATAGTCTAAAGTTC +TTCATCTTCTCAATTACAAAATTGGTTGTATATTGTCACCATTTTTCCTGTTTTCTTCCC +TCTTGAATTCATGTTGGAGCAAAATTATTTAACAACTAGCGTGACATCATCACTGACCAA +TCAAGGCAGAAGTCATTTTTAAACAGCCAACTGGGCATTCCTGTGTGTACACACTAACAG +CTCTGCCTAAGCCAGCAGCACAGATGCCACACTAGGTTTCTACCTTTCTGTTCCTGTAGA +ATGGCCTAATTATTTCTTGACTCTCCTTACTTCTGTTTTCTCCTTCATCTTTCTAGAATA +CATCTTTAGCTTCCTCCAAAGAAAAATGTGGAAAATTAACTTTAAAAGAGTGAAAAGTCT +TTTACCTTCATTCTGCATTGATGACTTGGCTTGGAATATAATTCTGGGTAGAAAACAGTA +TTTCCTTGGCATTTTTAAAGCATTACTCCATTGGCTTTTATTTTTCATTTTTAATATTTT +TAAAGGTGGGGTCTCTCTCTGTTGCCCAGGCTCGAGTGCAGGGGTGTGAACATAACACAT +TGCAGCCTCAAACTCTTAGCCTCAAGCAGTCCTCCCACCATGGGTTGCAGTCCTACCTGT +AGCTGGGACTAGAGGTGCACACCACCATGTTTGGCTTTCAATGGCTTTTGGCCTCCAGTG +TTGCTGATGGAAAAGTCTGATGACTTCTGAATTCCTGTTCCTTTGTTGGTGTGTGTGTGT +GTGTGTGTGTGTGTGTGTGTGTTTTACTCTAAACCTTCTTGGATCATTTTTTTGGATTTA +ACTTTTTAATTTATATCTCCTAAAGATGTATGATGTGTTTCGGTGCTAACCTTTTTTTTT +TTTTTTTCCCTCACTGTTTTGGTTATTCTATAGGGCCTCTCAATCTGAAGGTTAATTTAC +TTCTTTAGCTGTGGAAATTTTTCTTTTTTATTTCTGACAATCGCTTATTCTGTGTGTTCT +CTGCTCTCTTCTTTGCAACTCTACTAGATGTTCTTTGGATGTCATGGGTTGAATCTCTGT +ATTATTAACCTCTTCTCTCATAAGTGTGTATGTGTGTTTGCATGTCTATCTTTCTTTGAG +TTTCTCCTGTATTATTAATTAATTATAATTTTAATACCATTCTCTGTTTCCAGAATTATT +TCTGTTTCCTTCAAGATCAGTTTTCTTTTTGTTTGTCTTGACTTTTCTGAGGCATGCTGT +AACTCTTCCTCCAATATCTCATGATTTTTGGTTATCCATTCTTATATAAGAGTCAAGGTT +TGGGAAGTTGGCATGGCTTTTTTTTTTTTTTTGGCCACTATATAAACACATCATCCTATA +ACTCTCCTTTTTGAATGAGAAGCCTAATTCAGAGCTCGTTACTGGGCAGGTATTCCCACC +TGGCAGGGAAACCTGCCAAAGATCAAACTGCAGGCTGCAAGCCTCAGGACCACAAATGCC +AAAATAAGGAGGTGCCAACACTCATAACAGAAACTTAGGTCATCCCTAGACAGTTTATTT +AATTTATTTCACAAACAGTCCTCTGACTTATTTTATTTTATTTTATTTTATTTTATTTTA +TTTTATTTTATTTTATTTATTTTGGCTGAGAATGAAGGCCAGACTGCCAATCACTTCGAG +TAATGGAAATGGAAGGGCAATTGTTCCATATAATATGTTCTCTTTCTCTTCCTGTTTTAA +GCCCCACATCTCACCCTTACTCTCATGTAACCCTCCAGCCAAGAGCCTGCAGCCTTTCAG +GTTTCTAACCTTCTTACCTTCTCAACAGTCCTCTTATAGCACATTCTGGTGACTGCATTT +CTGTTGACCTATCAACATTTCCATTTGTTTTCTCCCATAAATGTGTTGAAATCTTATATC +TTTGTTGTTATATGTCTATTCCTCTTTGTACTTCCACACAATTATGTACATATAAAACAC +TGTTACTTCAGAGCCCCCAGTAGAGTGAGGACATGAATGACCAGCCTCAGTCTGCTATCT +TCACCCACAAGTCCCTTAACTGCTCTTGGAATTTATATTTAGCAGGGATTTTTTTTTCAG +AAAAATAATATGATTAGTCTTCTTCTAAAAAAAAAGAAAAATGAATTTGTTTGATTTTGT +TTATATTTTGCAAAACTTGATGGTTATGTTCAAGAGTTTTCAAGATAATTGAGGATTTTG +AATCAGTTCACAAATGTGTTAAGAGTTGTCGAATTTTCATGTTGTTGGCACAGAACTGTG +AGGAAATGAACCAATCCTAAATTAAATGTCTACTTTGCCCTGCATTTTCCTCAATTAGAT +ATTAGGCTTAACTTGTGTACTTGGTTAAATGGTTATATATACATATATATGTGTATGTGT +GTGTATATACCCATAAATATATATATACACACACACACACAAATTTTATTTAAAATATGG +TCTATGGGCTACTGCATATCAATATTTGCTAACTGTCCATGACAATATAAACTTTTACCA +GAATGTAAATCAACTAAGTTACTAAGCATACTTTGCAGTTAACATTTTTTCCCAGCAAGA +CATTCCCAATGAAAGAAGGAGTATAATGACTCACATTTTGTCAAAAAAAGATACTGATCC +AATCACAGACAGGTAACAGTTTTCAGATCAGCACTAGTCCTCAGTTCACATCTTGAGAAC +ACTTGCAGACATCAGTTAGAACAGTGCCTGGCAGAGAAGGCATTGAATAAAGTGCTAGTT +GAGTCTGACACGTGGACTTTTTGGAATAAGTTTGAGAACTATTATGATCATTTACAGATA +CGATGCTTAATTGTGTATCTCTTTCTTAAAACAATAGGGGAAGTTTCAATCATTTCTCAC +AGTGGAAGTTTTGTTTTCTTTCAGTTTGACAAAATCCCATAAACCACTTTGGTTTGTTTA +ATAGAAAGCAATCATTTAAGTTGCCAATGAGATAATATCCAAAACTGTTTCAGACCTCTA +CTTGTTGCCAACCCTTTCCTGTCTGTTCTTTCTCCCTACGAACCTTCATCCTGAGACTTC +ATGCTAGCTGATTCTAATTAACACCCTGGGATCTGCAAATCTTTATGTGTAAATTGCTAG +TGAGGTGGGTAGTGAATTTACTATATCAATATTTGTCTGCTATCATGAGGCCCTCCAGAA +TTTAAAAATGATCTCTCCATCTCTACCTGCTGATGAAAGGTAAGACATTTCTGTAACACT +ACTGAGAAGGTACTACCTCCTGAATATTCACTATTGCATAATCAGGCAATGGTCAGTCCC +CTTCTGTTGGCCCTCAAAATTCCTTGATTCTCTTCCCAAACACTTTTACCTGAAGAGAAG +GCCTGCCCACATTATAGCTCACTGTCTGATGCTAATCCACCCTTGGTTCTAGTTAGCTTC +AGATCCCAACGATTATATTATAGCACTGTCCTTCAGTCTCATTCAGACCAAATTCCTGGA +ATGGCCTAGTTTCTAAATGGTGCTTGTCTTAGACTGTTCAGGCTGCTATAACAAAATACC +CTCAGGTAGGTAGCTTATAAACAACAGAAACTTACTTCTTACAGCTGGGGAGGCTGGCAA +GTCCAAGATAAAGGTGCTGACAGATTCAGTGTTTGGTGAGGGCCCACATTCTGGTTCATA +GATGATACCTTCTTACTGTCCTCACTTGACAGAGGGGGTGAGGAAGCTCTCTGACATCTG +TTTTATAAGGGTATCAATGCCATTCATGATGGCTCCACCCTCATGATCTGATCACCTCTC +AAAGGCCCCACTTCCTAATATCATCATTTTGGTGGTTAGGTTTCAACATATAAACTTTGC +AGGGACACAAACTTTCAGACCCTAGCAAGGCTCTTACCATTTTTGCCTTTTACTCTGAGA +GTAGCACCCAGTCTTTCCCAGAGATAACCTTCCCTCTGATTTCTACCACTCAGTTGATGC +AACATTTAAGAGGCTATGTACTAAATTCCAACTTGATTAGAATCTCTAACCTTTTTCAGC +CATGAGTGCTCTGTCTCCTTTTGAGACCTACCAGCTCTTCTTTCCTAGGATGCCATGTTG +GTGGAGGGCATCACTTGGGGCAACTCCTAACAGAGCCAGCTCCAGTCCTGCTAAATTTCA +ACTTGCAAGCTCCACCCTGTCCAATCCTCAGATAAAGAGCACCAAACCCACATGGGTTAT +GTTAGTGCAAATAACCTTGTTAGTTTGTCACTTTATTCATTTTCAATTTTCCAAGTACAT +ATAGAAACATTATTCTTTTGTATTTAATGATTACCTTGTAATGAGCAAGTCAGATTAATT +GCTGTATTGCCATTTCAAATATGTTAGCCGTATTAGGCCTAGACCATTTCAATAGATCTG +ACCCAGAGACTTGGTATTTTTTATCTTTTCAATCCAATTTACACACTGTTGCCATGTTAG +CTTCTTCAGTTTGCCACATGAATCCTCATACTTGTGCTGAAGAACCTATGGTGGATCCCT +ATGGCATAACAGATGGAGTTCAAGAACTGCTGCCTGATCATTAAGCCACATCATCAACTC +AGCCATTGACTCCTATACCCTAAGCTGTCTTTCAGTTATTCATTTGCATGCCCTTAATTG +TTGCCTCTAATTTTGGCATATTGCTATATCTTTCTTTTGCTTTCTACTGATTCAGTTTTT +ATGCATCTTCTACAGCTCAGTTCAAATGCTGTCTCTTCAGAATAATCTTACTTGATAATC +TCAGGCAAATGTTATCTTCCCTTCTTTGGAGCATTCATTTTATTTTCTGTCATTTCTACT +CATTTGTTAGTATACTTATCTCCTTTTTTGAGTATTAGCTCCTTGAGGGTAGGTGTTACC +CCTTTATGCATCAGTGTACCATCATAGTGGCTAACACGATCTCTTTCATGTGGATAATAC +TCAATACCTAGTCACTGAATAAATTATTGATTGTTACAGAAGAGCAAATAAAGTAACTAT +TATAGTGGCCACTCAATCAAGGTGATTTGTGAGAATTTAAGGAGAACCAACATCAGGAGA +ATTTGGGCCACTCTTGATGAAGAAAACCTAATTGTGATGATACTTGAATATCCCCACTCT +CAAGAAAATAATTTACCTAAAAGTATTGATTGGTTTACAGATACCTGCAGAAACCTTTGT +TGTATATATGCAATAATGGTATTTGGACTAAAGAGGTAAGAAATGATGTTTTATTTGTAA +ATCTTCAGCAAGTCTATACTTAAGAAAATTGGCCTAATAATTGATTCACTTCATGGAAAA +TTAAATAGCCATTAAAAATTATACTTCACAGGTTGCAGTAACATGGAAAATGTTTACATA +ATGCCAAGCAAAAAAGTAGAACAAAAATTATATATATACTATAATCTGACTGTGTTTTTT +AAAAAATATGCATAAGAAAAGATTGAGGGAAAGAAAGAATCACCTCCAAAATGTTAACAG +GTAAGTGTGCTGGCATAACTATGGGTGCTTTTTTCTCCATTACAGTATTTTGCATATTCC +AAGTTTACTTTAGTGAGTTTAGTAGACTGATATTAAAAAGTGAAGAATTACAAAGGGAAG +GAAAATGCCTAACAGAATTAACGCTAACTTATTGGTAGCTGTTGATAGATTGATTAGTCC +ACTGACTTAGAATGATACACAGGGAGGAGTACAGGATTCTAAATTTTATTTAGATTAGTC +ATGGATACATCTCAGTGAATAATTTGTATCTCACTGATTGTCAATCACATGTATAAAAAT +ATTTTTGACCTATATTAAGTTTTGTGGGACATTTGAGAATTACTAATTTTTCCCCAAAAT +TGGGTTATTCTACTTGATGCTGTAGGAAAATATGGATTAAACTCAGATACAACTTTGCAC +AACTATCCAGAATAACACGAAGTAGAGTGGATAAGTAATGTCACTCCTTTCTAGAGAATT +ATGCTCTATAATTTGAGAATACAAGAAAGCCTAACTTCAACCCATGCTAAGGAGGTGCAT +TTACTCTGTTGTGTCTAGCTTTTAAATTTGCTTTCACAGATGTTGGATTACATGGTTACT +GATGATGAATCATAGGAAAAATGAACAGCTAAACAGCCTAATGTACCTTTTTATAAAAGT +GAAAGGAAATTAGGTTCCACTTCTGATTGTCATTTTTATTTACATTAACTTTTTCCCTTT +CAAAGGCTTGTATTCACACAAGGATTATTGAGAGCTAAGATGTGCATGAAAGAATGATCA +AATACAACAGAAGTGAGTGCTGAATTTTATGGTAAGAATAAGGCAGCTTTTTAATATATG +AAAATAGTGTTTCTGCATACAATCAGCAATTTTATTTGTGGTGCTTGACATTCAGTGTTA +ATCCACCAACTCTAAAGCTTATTAAAAATGGCAGGAGACACATTGGCAGCATAAAGCAGA +TCAGAAATTGTCGAAAACAATGAGAGGTTTATGATCAACCATAAAATTGCACTTATTTTA +GAAATCTGACTTTTGCATGGAATCCACAGGTGTAGAATCAATAGCCCACAAATAATGCAG +ACAATCCCAGCAGTACATTTCAAAGATCTCAAGTTGCAGGAGGGGGAAAAGAGCCTTCAT +TTGTTGTTTTTCCCTTTGTTCTCTTTTTATCTTGATGTGTGACACTCGCTCCTCACCGCT +ATCTCTTGGAATTAGCAATAGAATTAACAATAAAAAAATAAATGTCAGTCTTTCTTTCTA +AAAGAAGGAAACACATCAAAGAGACTATGAAGAGGCTGTAGGAGATCTGCAGTCGCTTTG +TCATTTCTGAAGATGTTTGCTACAAATTCCCTTAAGCAGATGTAAAGGCTATGGGAGCTA +TTTCTATTGTAACTTCTATATCAAATTCATCTAGGAGCCACTCCTAAACTCTAATTCCGT +AATTATCCAGGTGCCATGGGAAAATGAAAACTACTCAATGGTGTAGAAGTGGCTGAAGGT +ATGGGAGGATCATCTAATTCAGCGTGGCATTTTTGGTCTGCTACTTGCTAAATGAGTAAG +ATCTGAGGCCCTCTTTCATATTTCTCAGTAACAACTCTATGCTTTGTAGCATGTCTGACA +GACAAGTCATTTCACTCCTGCCACCAATGATGAGCTATCCTAGTGATGCCTAAACCTTCT +GCTGAAGAAATAGGAACCATGCAAGGAAAAATTAGTAAACTGAAGCTGACAGGATCTTGT +AGAGAGTACCCATTAATGAACGCCGTGGAGGATTGCATGCTTACCATTCATTTTCTTTCT +GCAATTTATATCCGATTTTCTACAGATTATGCAGAGGCATTATATGAATATTTGTTATAG +CTACACATTTAGAGAAGCAAATAGAATTATTTAATAAATGGGTGAAAGTGAGAAAAGAGA +AATAATTCAGTTCTCTTTTGCAATTCACAAAGTCACTTCCTTAGGGTGTATACTCCAACA +AAGTTAAGTGCCTTTTATGCTATTTGTCTGCTGGTAGTAAGTTTATTTACATAAAAGGGC +TTACAAATAAATATTAATTCCTGGTTGTTGGTGTGATTTATTACAATGTCCATAATTTCC +TTTATTCCAGTTCTAAAGATTTTGCCAAGAAAAGTATAAATCTCATCATCCAAATTTCAA +AAGAATTAATATATTTTTAGGCCAACAAAGATTTAGCATATTCAAATAATAACACTAAGC +ACTGTATCCTTCACACATCTGTACAGGGTGTTTATAGATTTATAAAAACTTTGTAAATCA +TGTGCAAAATTGTATAGCCATTTACAGCTGCATTTGGTTTTCTGAGGCATTTTGAAGGCT +CATTTTTCTTTCATATGTAGTATACCTATTGATATAAAGGAATAATAGATGTATTTATTT +ATAAGAAGAAGAATAGGGTGTTCTAGCTGTGGAGGCTACAGACCAAAAAATTGTGCATAG +TGTATATATGGCTTTACATAAAGCATTATAATAAATTAGTTACTGTATTTTAAAATATTT +CCTCCCTCTCAACCAATAAAAAAAAAGGCGATGATAAAACAGTATTTAAATAATTGGCAT +AAAGTGTAACCAGTTCATCACTACTTTGTTGATTAGGTGTAACACAGAATACCGGTTACA +TGGCCCTTGGTTAACTACTACATATTTTTTGGAGCGTTAGCCTTCAAAGACTTTCCACTG +CTTGGCATGCATGCCGGAAATGTAGTCAAACTCATTTAAAGCATAGTGCAGTGGCATGTG +CCTGTAGTCCCGACTACTCAGGAGACTGAGGCGGAAGGATTTCTCGAGCCCAGGAGTTTG +AGGCCAGCCTGGGCAATGTAGTGAGACCTTGGTCTCTATAAAACAAACAAAACTCTTAAA +TTTAGAGGGTTGATGGTAGGGGAAAAGGTTGAAGATGGACATTTGCAATACATTTTGAAG +ACTTTGAATGTGAAGATAGGGAGTTTGACTTTTATTCTCTAGGTGGGAAAGTAATGGTTA +GGAGCAGAGATTTACAGTTCACTAAACACTTTATTTGAATTCCAACTTTGCCATTAGTTG +AGCTCTATGACCTGTGGCACTCTCAGTTGTAAAATGGGTACAATACTCCTTTTTTAGATT +AGGATGAGGACAAGGAGGGTATATAATATAAGGTAATATAAGATAAAGATTGCATACTGT +CTGGCACTTATGAAAGCTTAACAAATGACAGCTATCACTATTGGAACCACCTGGGAGAAT +TTTGAGCATGCAAATACATAATCGCACCTATCATTTAGGAAGATTACTCTGACCACAGCA +TGAAGGACAGAGTGAGTGAAGCCTAAAGGAAGAAAGAATAGAATTATAAAGATCATTACA +ATTATCCAAGCAAATATTATTTAAAAGCCTGAAGTAGGGTACAGAAGGATAAATAAATGG +CATCATAAAAGAATAGCATCAACAGGGTGGGATAACTGATATGCACATGAGGTAAAAGCA +AGAGAAAAAATGATTTCAAAAATGTGAACATAAGGGTCTAGGAGGATGTTAACTCAAACT +TGGAAACACAGTGAAATGATAAAATAGGGTTTGGAGTTTCCATGGGACATTCAGACTGGG +ATGTCTGGCTGGACCACTGAAAATGAGGACCTGAAGTATAATGAAAAGTCTGGCTTTGGA +GCCTGTATGTTTGAGAGGCATTTGCATTGAAGTACAAACGGAAGCCAAGAAATATATAAC +ATGAATATTGTGAAATAGTAAGGGGAAAGAGAAAAGGTCTAAAATCGCACCACTGAGAAA +TTGCAACATTTATGATGGAGCAGGAAGATAATCAAATAGAGGTGTTCTAAGAGTTGTTGA +AAACATTTCAAGATAGCAAGAGAAAAGGGAGTAAGGAAAGGTGGTATAGTATGAAGCCAA +ATAATTTGCAATTAAATCATCTATATCCTTAGAAACTTCAGTTTTTATTGCAAAGGATTG +ACAAATGAGTGGGGGTTAAGAGGAAACAAGTATAAAATACTGCTCTGAGAAATTTGGTAG +TTAATGGAAGTCAAGAAATGTTTATATTTTGAGAAGGTTTAATTTATGTATTTTGTTCAA +AGGTTACATATTCAATCTCATTGGATGAAAGTTGAAGTCTTTTCAGAATCAAGGTTCAAT +GATTGTCTTTGTTTCCCTTCTTTCTAGTTTCTCAGTTTCATAGATAAAGGTCAAGATAAG +TTTTTTATACACACAAAGTATACACACAAGAAACCTCGCCTTAATAAAGTATGACTTTCT +CTAGTCAGTTGTCTCTTCCATTGACCTCATGATTATTTCAGAATCTACATATTCCTCCTA +ACTCCTCCTCCAGCTTCTCTTTATTCTTGTCAGTCTACTTCAGTGAGAAACACAGACCAT +CAGAAGTGCTGATTCTTTCAACTTTCCACCATCAAATCTAAAATTCATACGTGCTCTGAA +TATCCTGGTTTTTACTTCTCTCTTTTTACAACGGTCTGGGCTGATCCACTCACCTGCTAT +GCTGGATTTCTCTCCTCTGTCTTCATCGGGAACCTTGTGCTATTAGTTATTACCTCATCC +CCATGTATATGCAGCTTCAATTTGATGTCTTCCTGTCAGTCATCAAACAAGCTCAAATCT +CAACCAAATATTTATAAAGTCCTCACTTTACTACCTCTCTCCAGCTTCTTTTATAAAGAA +ATTGATGTTAATTTCAAAGCTTCATAAAGCTTGGCCAATCTTTAACAGACAGATACTTGC +CTTGCCTCCTAGCTTTGCAAGTTTCTCTGCTTGGAATGTCATTCCCACCTCTCAACTGCC +CTCCCCACCCCAGGGTTTTCTATACTTATGTTGTCATTCTCAACTTAAATATCACTTCAT +TATAACAGTCTTTCTTCAACCCTAGCCCAGGCACTTTTCCTTATTCTAGTCCTTCTAGTC +ACCTCTTGTCTTTCTTTCCTAAGAGACTGTAAATTCCACAAAGAAGAGATAACGTGTCTT +GTTCATTCTTATGTGGTGTATACTGCATACAGCCTGGCATAGAGTAAGCCCTCATTAAAT +TTTTGTTGAGTGTTCCCTGCAGTTTCTCATTAATACATTCCCTAGCACATTTATTATAAT +GTAATTTACCTAAAGAATTGATTTACATTCAGTTGATTTTTATATTAATTGATTTTTATA +CATTGAATTTTGCAGTAAACCAAGGAATATTTTCATATGAAATCATATTTTCCCACTAAG +AACAATTATATTTTCAAATATGTTTCCACTGAAAGAGTATTGACCTCAACATATGAAAAA +ACCATCCTTGACATTTCTGTATTTATTTCAACAAGTATTATTTCTCTGCCATATGTATTT +AATTTTTCAGTTTGTGCATTTAGTTCTCCTGTACCACGAATAACTTAGTCAACCAGACAC +ATAATGCATACATATTATGTGTCCTGTTGAATATTATGTGTCTGGTTGACTAAGCTATTT +GTGTTATAGGAGATACCTATACCACTTAAGGGTATACATACTGAAATATCAAATAGAATT +ATCTCACAATTCATTGAGTGTTTTAACTTACTCATGGCTTGAGAGCCTCAATGACCCTGC +CTTCAAGCCAAGTTTATTTTAGCAGAGCAGTACATGTAGAAGAGTGAAACGAAGTACTAG +AAAAAAAGAGTATGGAGATAGAAAGGTTCCTGAAGTGACAGCTGAAAGACGTGGACCCTG +ACCCAAACACAGTCACTGATTAGCTGTGTGACCTTGAATAAGCCATTTTTTTTTAAATCT +GCTTCATTTGCAAAATTAGTGTAAATAATTTATACCTAATTTTTAAGAGGATAAACTTGC +CTTAAAAGTGTATTATATTTGTTAAGCATTGTGAGGGGTACTGGAATTCAGGCACAATCC +TTATACACAAATATGTTAACTTCTTCATATGGACACAAACCAGGAAGGTCTAAAATTGAA +TGAAAATATGCTGTTGTATTTGAGGTGATTAAGTAGCTAATGAACAGAAGAGACCATCCG +TGCTATAACATATAAAGCAAGTAAGATTTCTTGTTAAATGGTAGGACCTCTTTCCTGTTA +ATACAATAATAATAAGATTGAGGGAAAACAGCATATAATTACATGCTTGCATGTAAAACC +CACTCATGTATATATATTGAATAAAAAAAGGAAAGACCAGATGGGTTACTCAATGAATTA +GATTGTTTAAATATTGGTTACACATGTGGAGATATTTTAAAGTGCATATATATATATTAT +ATATATATATATATATATACACACACACATACATACACACGCATATATATGCATAGATAA +ATATAGTTGACTCTTGAACAACACACATTTAAACTGTGTGGGTCTACTTATACACAGATT +TTTTTCTACCTCTGCCACCTCTGAGACAGCAAGACCAACCCATCCTTTGCCTCCCCCTCC +TCAGCCTACTCAGTGTGAAGACGACAAGGATGAAGACCTTTATGATGATCCATGTCTGCT +TAATGAATAGTAAATATGTGTTCTCTTCTTTATGATTTTCTTAACATTTTCTTTTCTCTG +GCTTACTTTATTGTAAGAATATAGTATATAATACATATAACATAGAAAATATGTGTAACC +AATTCTTTATTTTATCAGTAAGTCTTTTGGTCAACAATAGGCTATTACTAGTTTAGTTTT +GGGGAAGTCAAAAGTTAGGTGTGAGGTTCTGACTGTGCCAGGGGCTAGCACCCCTAACCC +ATGTGTCGTTCAAGGATCAACTGTACATGTACATATGTATATGTAAATATATGCCTAGAC +AAATATGTATGTGTGTACGTGTGTGTGTTTTTCATAAATGTATAAGGTTAGCATTTCACA +TAAAAGGAAAAATAAATAATTCAAAAAATATTGCTGATTTATCAACTGCTTGAAATATAG +TAGAAATGTAGAAATTTTATATTATACCCTACCTCAAAATATGTTTCAAATGAATAAAAG +ATTAAATGATGCATTATATAAACTTAAAAGAAAATACAAGTGAATAGTTATATTTAGTTG +GATGTGAATACATTTTCTAAATTCTATCTAAAACCAAAGCTAGGATCCAGAAAGGAAAAC +AGTTTTTAGACATGACCTTATTAAAATTTAAACTCTGTTACATCAAAAACATTCATAAGA +AATATTCAAATGACAAACTAGAGACATTTTGCAATGTATATGACAGAGTTAATAATCTTA +ATAAAAGAACTCTTTCAAATTAACAATTATTAAGACAGAGACTTGTAACCAGAAGATTTT +TTTTTTTAAGTAAAGGCAAAGGGCTTAAATAAGAAATTTACAAAGAGAAGCGAGGAAGGC +AATGGGTTGATAAACATAAAAAAACTGTTCCACTACATTAGTTCTTAAAATGCAGATAAA +AACAAGATGCTTCCTGTTGATAAGGGTGTGAAGAAATGGTCACTCACATTCCCTGCTAGT +GGGAATATAAGTGTGACCTTTCTAGCAGACAGTTTAGAAATACCAGTGTTGCCAGTGGCA +AATCTGTGTGGGTCTGCGGCAACCTCAATTCTCGCGTCCTCAGATGAAAATTCGACTGAG +GGGCATAAGGCAGGCAGAAGGAGTGATGGAGGCAAGTTTTAGATCAGGAGTGAACATTTA +TTAAAAAGCTTTAGAGCAGGAAATGTTACAGTAGGTAGCTCGTCAGACATGAGCACAACA +GGAGAGGGTTTCCCCCGCCCTATCCCACACACCAGCAGTGTCAGGCGATCCTCACGTGAT +GGTCAGGCAGTTGTTAAGCGGTCTCTCTGAAATAATAATTGGTCACTGCCAGCACCAGGA +AAAGGCAGTCTCCCCCAAAATAGAAGCATCTGAAGCTGGTGATCAACACTTTCCCAATAA +GATCTCGGGAGATGGGCAGATGGGCTCACACATGCTCACTAAGAGGCAAAATGGCGGAGT +TTAAATGGTATATGACCTCCTAGGGTCATTAAGTTGGTAAGGGAAGAATGCCTCTGTAAA +CACACTGCACATGCTCACCTCTCAAGTGCTAGCAGGCCACTGTGCATACGGACAGCCCAC +CCCAGGGAAGAATCAAGGGAAATGGGATGCAAGACCCTGCAAGTATGCCTACATATAGAA +CCCCAAGTCAAAAGGTCAAACTGTGCACTTGTCTTTCAAGTTACCCCCGTGGCCTACTTC +CAAGTGTAATTTCCTTCCTTTTGTTCGTGCTCTAAAACTTTTTAATAAACTTCCACTCCT +GCTCTAAAACTTGCCTTCATCTCTCCTTCCGCCTTATGCCCTTCAGATGAATTCTTTCTT +CTAAGGAAGCAAGAATTGAGGTTGCTGCAAACTCATACAGATTCACTGCTGATAACACTA +TAAGTATTAACAGCTTTTAAAATGTGTGTACCCATTGATCCAACAATTTTATCTTTAGGA +ATTTAAGAAATGATCAAAAATGTAACCAAAAATAAGTGTACAAATATGATCACTTAGGGG +TTATTTACAATAAGGAAAAATGAGAAATGGCTACCTAAGCATTTTGGCCAAGGTAGATTT +AAAAAGTATGAAGAAATTTTTATAATCTTTTGTTAAAAGCAACTCTGTAGCATTCATCAA +GAATGATATTTCTTAAATATTTATACCCTTTGACATATTGATTCATATTCTAGGAATTTT +TCCTAAGGAAGCAATTGGAAAAACAGATAAGCTAAATTCATGAAGGCACCCATTGCAACA +TTATAGCAGTCTATCATCCATTGGATTATGAGCATTGGGTAAACCAATAATACAGCCTTA +AAATTGGAAAGTATGTGCCTATTAAAAATGTTGTTTATACAATGTTCCCAATGTCTTGGA +AATTTACATATGTGGAACATTAGAGTAAGAAAAGAGACTGTTCCTGGGTCCAAACCAGCA +CTCTGTCACCATCTATTCTGCCTTCTCTAAGCTCTAATTTCTTAATATATAAAGTGGGGG +TATAATTGTTCAATGCTTATAGGGATTTTGTGATGTTGTAAGGATTAAATGAGATAATGA +ACATAAAGTACTTACCAGAGGCACAGAGCACTCAATAAAAATTAACTATTTTTTAATGAC +CATATAAGAGTCTATAAAAGGATGGCTATAACTGAATATAGAGTGAAATAATTTACTGCA +GCATTAAAAGTGGTTATCTTGGAATGGTGCACTTATAAGTGATTTTTTTTCTTGTGTATA +TTTTCCAGATTTCTTTACTTTCATGATTTTTTAAGTATATTGGTTTTGTTTTTTATTTTG +TTTCCAAGTGGAAGATAGATAAAGGATTCTGAAAAGAAAGAGTAAATCAGACAGGCAGCA +GCAGTAGCCAGGAGCTGGACAACCAGGGCAGAGCCTCTGTCAGCCAGCACCATCTGCCAC +ATAGCAAGTAGGCAGCATCCTGGACGAGGAGGTGTCTCCTAGTTGGCAGAGCAGTGGTTC +TTCAGTCGTGGTGTGTATCCAACCAACAATGGAGCCTGAGAACAACAGGGATGCCAGGGG +CCCAAGTCCAGAGCTTTTAATTTGATAAGACTGAGGTGAGATATAAGTGCTTGAATTTTT +AATAAAGACTCCACCTGTGATTCTAACTCATACCAAAATTTGAGAATCCCTAGGCTACAG +CATGGTATGAATAAGGCCAAAGTTCCATGTTGCACCCCCGAGGGAGTCCCATAGTTAGCC +GCTTTGTGTGCCTGCAGGCTGCATGCCTGTTCATTGCCATATGTCTAACCAAGCCTGGGC +CAGTTCAGAGCATGAATAGAAAGGAGCAAATTACCTCCTTCCTTTTTTCCTTTCCACTTC +CCTGCCCCTCCACTACTAAACCTATAATCCGAAACATATATCCTGTTATTAGTGAATCGG +TAATAGCACCTTCACTAGACAGTAAGGGGGTATATTTTTAAAAGAAATAGACCTAGACAG +CTAAATATGGTAGTTGATGAAGATCAGACAAATCAGGCAATCTAAAAAAGTGGTCAATTT +GGTGAGATTCATGTTTAAGAGGGCAGAGTAGCTTTGCTTTACAGAGATTAGTGAGAGTTT +GTAGTTCTTTAGTGTTCATCTGGAATCCCCTAGCATTTTCCTCATACTTTTGCTGCTATC +ATCTATCTGCCATCTTGTGACATTACATTAAAATATAATGAGTTCTAGGCCTGAGTTCAT +CTGAAGTTCAGGGTGTTGCAACATATAAAATGAGCTGACGCCATGGGAGTCAGAAGTGTT +TTCATCCAATACAATATCAACCTAAATGCACTCAGTAAGTGAAATCTGCAACACTCAGAC +ATCTGATTTTTACTTGCCCTTTTGCAAATTCCATTTATGTTTGCTTTTGAAAATAACTTT +CAATTAAAATCATCCCATGGATTTTACACTGTGTTCAGTTTCTGATATCAGAAGGTGGTT +GTGTAATTACATTAGGGTTGGTTGGGATGTGCAGAAGAATCACTTGTGCTCTTGCCTTTT +TAAAGTGGAGCCCAGTGGAGCAAATTATATCACTTGAATATTCCTGTAGGTCTCACCCAA +CTTTGCTTCTTTTCTTGTGGTTCCCTTTAGATGTGATTGTTTTAAGCGTCATTACCTATA +CCTTTTTGCTCATTCATTGTGGATATATCCATTTTCACTTTGCTTCATATTAACAAATCC +TCTTGCTTCTATGGTGGATTAAATAAGCCAGCTTCTTTCAAGGGTTGGAAACATCAAATA +ACCTTGCTGTTTGTCACTAGTTTCCCTGTGCCATAATGAAGCTGCATTTCATGGCTTATG +CAATTGACACCCAAAGAGAACAATGGGTTTGTAGTGTAAGCATGAAGAAAACAGTTCCTA +ATATCTGCTGGACTTAGGTCCGGTCCCCTCTTCTTTGAATTCGAGTTATGGCAACCTGTT +TTTTCATTTTTAAAATGAAGATGATAGTATGAATTTTGCAGGATTATTTATACATTAATA +ACAATGTACATAGAGAACCAGGGATATAGTAGGCATTTAATAAATTGTAGCTATTGTTAT +GAATGCATAGAAAGTATATATATATATACACATACATATATATAAATTATGCAAAGCAGA +AAAAACTAGCTAAAGTAAATGATGACAGAATCAAGAATCAAAACTGTGTTTCAAGTAGTA +TTACACTTAACAAAAGCAGGCTGCTAACTGCCTAATTCAGTGGGTATTTTAATATCTTTG +TGCACTATAATTTACTGCCATATTTGTCCCTGTTGACCACTTTCAGTCTCTTGTAACTTC +ATATGCCCTTGACCCATTCTTTCCTTATTTTCTTCTAACCTCTTTGGCTCATCCGTCTTT +GTCTCTTTTAAATAAGTGGTTTCTGCCTCAGTTGATCCTCTTAATGATGGTATTACTCAG +GTTTCATCCTCAACCTTCTGATCTTTCCATTTCATGTAGCCTTTCACGGATTTGACTAAT +GATTCACTGGTAAACATCAGACTCACATTTACTGACTGTTACCTATCAATCCTGCACCAA +TATTCCAAAAGGGAACTTACTGAATTTTCATATGCCTTCAATTAATTCTCCACCTGGATG +AATGATATCAGTATTTACACAGATACACAAACCAGAAATCTAGACTTTTCAGTGGAAGGA +ATCATAGGTCAACATCTTACTCAGGACCTAGAGGACAAGTTTTAAGAATAGCTGCTTCAA +CATATGGAACATAACAACCAAGTACAATGTATGCACATTGCATGAAACCTGATTCGACAA +TCTAACTGGAAAAAGACAGTTTTTAATCACTAAGAGAAATTTAAATAGGATTATGCATTG +TGGAATATTGGGGATTATTTTTGATTTTAATTAGATGTGATAATATCATTCCAGTTATAT +ATACATATAATATAAATATATACTACACATAATTATAAATATATGAAATCGATGTTATTT +ATATGAATATATATTATTTCTATGAATATATGAAATATATATTATTTACATTTATATATA +ACATATATTTATACATTATATATACTAATATACTATTACATATTAATATAATTCCAGTTA +TATATAATATTCCAATTATATATGTATCATTCCAGTTATATATGTTATGTAATATAAAAT +ATATATTAGACATCTATTATATATACATATAACTAAAAGATAATAACTAAGGATGATTAT +AAAAAGATAATCAGAGTACTTACCCTACAGGTTCCTTTTAAGACTTTACATGTCTTACTT +ATTTCAGTTTATTTCAGTACTTACACTGTGTTCAGTTTTTGTTATCAGAAGGTGATTGTG +TAATTACATTAGGGTTGGTTGGGATGCTCAGAAGAATCATTTTGCTGTTGCCTTTTTAAA +GTGGAGCCCAGTGGAGCAAGTACTATCTGGTAAGTACTCTGGTTATCTTTACAGATGAGG +ACACACACACACACACACACACACACACAAACACACACATATATATATATAACATCATAT +ATATATATAACATCATATATATAACATCATATAACATCATATATATATAACATCATATAT +ATATACCATCATATATATATATATATATATATATATATATGCGCACACACACACACACAC +AGCAGTTAAGGATGCATGTTGTAAATTGAAGATTGAAGAACCTGATGTATTCTAGCAACA +AATAAATTGAAAAGATAAAGAAAAAACAGAGGCAGTGGTGATAGAAGACACAAAATGAGC +AAAATAGTGGTAACTGTGAAAGTTGGGTCATAGGTGCATAGTAATTCACTATATGATTCT +ACTTTTAGGTATGTTTGAAAATTTTCTATTAGACATCTAACAAATGATATTTATGGGCAC +CCCACTCCAGTATCAAGATCACCAGGAGTGGATCCCTGGAATCTGCATTCTTAAACAGTT +CCCCAGGTGATTCTTATGTGCTCTATGATTTAAGAACCACTGTTGAGATTTAAGATGTCA +GGATCATTTCTGTAATAAATTTGTCTCTCCCCAAACAACAATTGCTGCTGTTGGAGATGT +CCAAGAAAAATCTTAACTTCAGGGATGAAAATATCAACACATCAATCTCAAAGATGAAAA +ACACTAGCAGGAATTCTGCCACACAGCAGAGCCCAGTTACATTGTGGGGACATAAATCTG +ATCTATTTCATGAAATAGAAGTCACGTTTTTAGAAATTACCTACTTTTTATTCCTAATGC +AATAAAAGATGACATTGTCTCTATTGAGCAAAAGCAGACCTGGATAAGAAGAGCATGCTA +CATAATGAAAATGACAATAACTGAAATAAAAGTCTCATTTGAAAGTAGTAAAAAGCAGAC +CTGACATTGCAGATAATCAAATCAGCCATACCCAGAATACTGAGAAAATGAAATCATGGA +TTTTAAAAATGACTCAAAATATAATTGGCATAGAACTCAGTCATGAAGATAAAACCTATA +GACTCAACAAATGGATCAAAATTAATCATTAAAGTTATAACAAAATGTATTTCTGAATTC +TGGGGATAAAAAGACCCCAAAATATTTGAGTTTATTATATCTCAAGTAATGCTAGTAGTC +AGGGTAATGACACCAACTGTATCTTGTTATAATTTTTAAATTATTGGAGATAGTGATGAT +GAATTCCATGTCTCAGAGCAGGAAAGTCACTTTACTTCGACAGGAGTAAAAGTTACCTTT +TTTCGAAGTTCTCATCTGCACTATCATAGACCTTAAGACAACGAAGCAACTCTAGTATTT +CTGGGGTGAGGACAAGGAAATACTGAGTTGTTATTCATATAAAAAGAAATCATATGATAG +GTAACATAGCAGAGAATATGCCATCCAAGAAGCTGTTTTGCCAAAGTTATTCACACATAC +AGTTAAAGTCACTGAAGGAGAAATCAAGAAAAGGGTCTTACATCTTTTGACTCTTATTTT +ATGATAATATTCTATTGCATCAATCCTAAATTTAACTTTTCCTCCCGCTTATTTTGTCAT +CACTGAAGTCAGGATGCAATCAATAGTGTCCTACAGTTGAACTTTGACAGGTGGCAGTTG +TGACATAGTTGTCATTGCCTGCACATGCACACATCTGGCTGCAGCTCCTGTTGATGTGAC +TGAACAAGGGCAACCCCTTGATGCCTCAAATGAACCATTTCAGCATGATTGGAGAAAGGA +ATATGAATTGTGATTCTTGCCTGAAAACCTTCTACTGGCATCCTCTAGGAAGATCAAGAA +AATATAAGCACCAAACTTACAAAATGGTGTTAGCAGCTTGGGAGAAAAACCCTGCAGATG +GTAAAAAGCACTTTGTGAAGAATGTTGCTTTGGACTATGGGTACATATGGGTAGTGTTGC +CTTGGGTTATGGGTACATTATGCTATTCTCTCTGTTATTCTTGGAAAGTTTTTGAAATTA +AAAGTCTTTTTAAAAATCAGAAGAAGAAGAAAGCAGGGAGAAAGCAAAAGGAGATAATGC +ATTCCTAATGCTCCTGATTGTCCAGATGATATTGAATAGAAAAGCACTGAGATGGACATG +TGGACAACTCAAAGTTGCAAAGAGATACAGCAAAGTCAGTCTAACCAACTAAATATATAT +GTTTCTTTTAATATATGAACAAGAGTGGTGTCTGATGCAAATCTGTACTTAGGTCATGTA +CTTAGGTCTGTACTTAAAAATCAAGTATAAAATAAAAATTGTAATAACAAAGCATTATGT +CATAGTTTAATTTGAAGCGTTTTTTTTCTTCCTTCGTAGCACATACAGTGGTACTTCTCA +AAATCAATGGTGTAGTGGATTTTATGAACTATAGAAATAACTATTATTTTTTAGGCACTT +GCTATCTGGTCACAGTTTTAAGGACTTTACGTATCTTATTTATTTCTTAAATGGACCCTG +TAGGGTAAGTACTCTGACTATCTTTACAGATGAGGAGATTGAAACACGAGAAGCTTAAGT +AATGTGTCCAGTATCTCACAGCTAGTAAGCAGCAGAGCCAACATTCAAATCCAGACAGTC +TGACACCAGTGTCCAAGCCTGTCACTACTATATCAGTGCCTCAGAATGACTCTAGACTGG +GGGCATCATTGTGATCGCTTTATGAATGTACAGATAAGCAACTAAGGCCAGGAGAAGTTA +AGCAGCCTGACAAGAAGTGTGCGGTATAGTGGATAGACTGTAATCTAATCTTGTTCTATG +TATACACACATACACACACACACACAGACACACACACTTCCCATTATTGCCACCATTGGA +AGCAAAATTGAAGAAAACAGATACAGTACATTTTAAAAGAGAGATTGTTGGCTGTTGGTT +TATGTTATTTAATCATAACAACAGTGCTTCATGGCCGTTGCCATTTTCCTTTGTGTAACA +GCTGTAGAAATGAATTCTATAGAGCACAAGAAACTTGTGGCCATTTCCAGAACTCTTCTA +TAGCAAAACAAGAATGCGGACCGAGGCATATTTGCCCCTAAAGCCCCATCATCTTTGATT +TTTCAAAAATAATTAAACGCACGTACTGACGCTGAAAGGAAGAGTGTTGCTAAGCAGAGG +TTGCACACTGGCAGCTTGCAGTTTGAATTTTGCCTATAGATGTGGTTGGCTCGTCACATG +CCACGTTTTCTTTAAAAATCATGTTAATTTTTAAATACTGAGAGGTCACCTAAAATCTGG +ATTTTTGCAGCTTCTCTTGAAAAATGAGAGAATTTGGCAATATTACATCTGAATCCCTGC +ATGACAGTAACAGCTGGAGCTGAGTAGCCATTGCTTCCCTAATCTAGTTCCCCAGTTCAC +CTCTGCGCCAACACTCAATTATTCTTTTACACAGGTTGACTCTGCCTGCCTGGCTTTTAG +TTGGTGACCTCACATCTAAATGGCTATTATAATTAAGACAGCTATTTACTTCAAAACAAT +ACGCTTTGACAGTTGCAAGCAAGTATAAAAATTTGTAAGTTAGAAGGAGCAGTGAGATCT +GTTTTGTGATATCCAGAATTATATGTGGTAGTCCTTTCACAGAGAATTCAGTTCAAGCAA +GTGATTCATCTCTTCTTTTTTAAAGTTGATTGTAGTATTTATGTCTCCAGAATTTTAAAA +AATTTACATTTTACTTTCACATTTTAAGATCCTGAATACAGAGTTAATGTTAACATTTTA +AGACTTAGTAACTAATTACAATTGGATACTTAAATGTTAATAATATTCACGAGAATCCAG +ATTATATGTTTAAAATGTATGTCAGCAAACTTATTTCGAGAGAATTTTAAGGGCTGTGGA +GAAAAGAGATTTATAAATTCAAATAATTGCAGTGTCTGAATAGATTCTTTCCTTTTTTCT +TTTTTTCTACCTAAAAGCTTATGACTTTTTGACATCAGTACTTTATTTTACTTAAAAAAT +TCTATATCTGACCCTAAGTAGTTATCAATATTAGAAAAAAAAGTAATGCTGATTTCTATA +CAAAAGACTTATCTATGAACAAATGATTAGTATATTGCTTTAAAAAATTTAATAACAATA +ACAATCCTATGTAATGTTTAGATTTATTTTGATTATTAATTTGAAGGGGCATACATTTAC +ATTATCTTTAAAAGACTTCATATGCTATTGTTCAAGTTGATACTGGTACTTACCACTAAC +AGTTCACAGTGGCTAAGAGTGGTACTATAGGAGGCTAAAATTATTCCTGGACAAACACAG +AAAGAAACACAAACAGAGGAGGAATGTGGAACAGCCTCCAAGATAGACTAAAGTTACACT +GTGATAGGGAATATCCACCTAAAACATGATCTCCTCCTCCTCCTGGCTGACTTCAAACCC +ATCTAATGTGTACTTCATCAGTAGAATGTAGGGAACATGCACCCTCAATATGTTTACATT +TATTTATATAAAAATTCAATAAATTTTCCACTGCAGTAATGTATGTCATACATTATAAAG +CATATCCTAATAAGAAATTTTAAAGGATGAGATAACAAAAGTAGAAATAGATGTTCCAGT +TTTTTCCTCAACTCCCATAATGGACTACTTTGTTCCTTCTTCTTCATTGTGATCATCCCA +GTTCTTTTCCAAATTCTATTCTACGCAACACAAGTTCAACGTCATTTTAATAAGAATTCC +ATGAGAAAGAGTTTCATTTTCAAGTAAGTTTGGGAAATATTAGGTTAAAATTAGATAGGT +TTTCTTGTTGTGTGACTTCTCATCTTTAATACAGAATCCTGTTGTGAATCTTTATGAGGG +AGAGCGTCTATATGGCTAATACTCCTCCAAGATCTCTGGGAAATCCTGCTGTGTTCAAGT +TTTCTGAAAATCATCTTTGCTTGCTGTTTGCCAGCTCTTTCCATAGGGTCTCCACTTAAT +CCCAGGAAGATCCTGGTAAACATTTCCAACCTCTTTATATTACAAACCTTTCATCTCACT +AAACTTTCCCTTATTTCCTAGGACCAACGTCCACCCCTTTGTACTCAGAACCTAAGATCT +TTTTGGATAAGCCCTACTCAGGTCTTAGCTTTTGCCCTTCTCTTGTCCATGTACGTGGAG +TACCATGGCCTTTCACAAAACTTGCTAGCATAGCTTCACTACAGTTTCTAGGATGAATCC +TGGCTTTGGGTCAAAGAGAATTAAGATAGGTCTGCCCCATAATTTGGGACTCATCACAAA +TTCACTCTTCCTGCTTGATCTTGATCATGTACAGGAACACTTATTCTGATAACCTTCTAG +TTCATAGGACCCAGTCCCCACTTTGTTCTCCATTGATAACCAGGTTACCGCTCACCTGCT +TGGCACCTGTCCATTTCAAGAAAAATATTATTATTATTATAAATACTATCATTGTTTTAG +ACAAAAGCAAAACTTGGGCCTGTTTTACAATTCAATAAAATCAAACATTTGTGTTTGATT +TGAGGGTCAAAGATGTACATTTTTTTTCAGCTTTAGTATTTTTTTAAAGTATTGCTCAGT +AGTGAGTCTTAATATATGTCAGAATAGTACAGTTGAAAAATAATATTGACCCACTTTAGT +ATTATGAATGTGAATCCTCATAATTATCTTCTTTTGTTTTTGTTTTCTACCTTTTTTATG +ACATCAACATACCAGAATGAACAGAGGCAGTCTTTCTTGGAGAAATATTTCTTTTTAGAG +GCAAGACCACAGATGACTTACAGACATATCCCTTACTTTTCTAAGCTAGCTTGGTATTTT +GTTTTGTTTTATATTTCTTTTGCTACAATAGTAAAATATGGTTTGGCCATCAGATGCTAA +TAAATTATGGCACTTAAAATGTGGCAACATTTGTTTTAAAGCTTAGGCTATTCGCCACTC +AATACGTAGTGTAAATATTTCCCCCTACCTTCCTACCCTGTAGGTTCATGAGCCATCAAA +TACTGTAGTAAAACAATACTGATCCTGCAGCAAGATATAAAAGAAGGCTAGCAATAAGGA +CAATGTGATTTTATACTTTAATATCTAAGATTAGATCCTAAGTCCAATATAAAATAATCT +CATATTTAAAATTCAATATCTTCTGACTTCCCAGTTCTGAAATCACTTGAGTAGACCAGT +GCAATGCATTCAGGACAAGCAGGTTTTTTGCTGATATGGTCCTGAACTAATACTGAGGAA +AATTTGAAATTGCCTAAAATCAATCCTTATATTGGTCTCTGTTAGTGAGAGTTAACCACA +GCAGATTAATGAGATTAGAAAGTGAGGAATAAAAGAGACATTTATCCAATAATCTTAGCC +ATAGAGCATACTGACTACTAACTAAAAAGATTTATCCGACAAGTAAGAGTTTTTTTTTAA +TAGGAATCTATCCTGTGTTTCAAAAATTACAATGCAGATGCTAACACCTTAGTTCTACAC +TTAGCCCTTGTTTCATGAATAGATTTATCTTTTCCTTTTTCACTACATTTCTTTGCACTC +TGTCATCAAACATTGATAAGTCTTAAAAGTACATTACTAGATTCTCTTCTCCACTTAAAC +TACTATCCCATTTTCCCTGCCTTCATTTTAACACTTCTCTAATGAGTGTTTCTTTTTTTG +TTTGTCCTGTGTTTGTTTTGAGATGGAGTCTTGCTCTGTCGCCAAGGTGTAATGCAGTGG +AACGATCTCGGCTCACTGCAACCTCCGCCTCCCAGGTTCAAGTGATTCCCCTGCCTCAGT +CTCCGGAGTAGCTGGGACTACAGGCGCACGCCACCACACCTGGCTAATTTTTTGTATGAT +AGTACAAACGGGGTTTCACCATGTTGGTCAGGATGGTCTTGATCTCCTGACCTCATAATC +CGCCCGCCTTGGCCTCCAGAAGTGCTGGGATTACAGGCGTGAGCCACCGCGCCCGCCTCT +AATGAGTGTTTTGAACCCCTGCCTCTTTTCAGAAAAAAAAAAAAATAGTAATTGCAGAAT +TCTCTAGTAAAATGACTTCTGCCTCAACAGCCTATTACAACAAGTATTTCCAAGGTCACT +GACAACCACTTTCAAGACAAATCAAAAGATTTTTCTTACTCCTTATCTTCTTTAGAGTAT +CTGGCACTATTGATCACATACTTTTTTTTTTTCTTTTTCTTTCTGGCATTTTAAAATAAT +TTTTTTCTTTATTCTCTAGGATATGAATTGCCTTTTCATTTTTTGGAGGTCAGATTAAAT +TTTTATTTCTCTTCTAGTACACACATTCAACTATCTAGAGTGGCCCAAATTATATATAGT +AACTCAAATTTGAGTTGTAAGCTGCCAATAAAATCAGTTGTAACTGAATTTGGTGTTTTC +ACATTTATGGCCAAATACATGAATTCTTCCTTTCTATAGAAGAGCTCATCAACCTCCTAC +ATGGTAGATTCAGGAGAGGCACTTCCAGAAAAAGTAACTCCATTTTCTACCCCTTCTAAA +TTCTATAAAAAACATATTACTACTGGGATTGAGAAATCTCCAATTATTTTTCTGGACACA +CATAAATGATCCTTGTTGCAGTTTGATTCTTGGACATCCAGTTGATATTAATTTTCATGT +AATTTATGACGAATTGTTTTGTCCTAGGGCTAATCTCTCTCTGTCCTTCCCAACCATGAA +AAACACAAGGCTCAGAATGTTCTTTTTTTTTTTTTTAAATTATACTTTAAGTTCTGGGAT +ACATACATGTGCAGAACATGCAGATTTGTTACATAGGTATACACATGCCATGGTCGTTTG +CTGCACTCATCAACTCATCATCTACATTAGGTATTTCTTCTAATGCTATCCCTCCCCTAG +CCCTGCCACCCCCTGACAGGCCCTGGTGTATGATATTCCCCTCCCTGTGTCCATGTGTTC +TCATTGTTCAGCTCCCACTTATGAGTGAGAACATGTGGTGTTTGCTTTTCTGTTCCTGTG +TTAGTTTGCTGAGAATGATGGTTTCCAGCTTTATCCATGTCCCTGCAAAAGACATGAATT +TATCTTTTTTTATGGCTGCATAGTATTCCATGGTGTGTATGTGCCATATTTTCTTTATCC +AGTCTATCATTGATGGGCATTTGGGTTGGTTCCACATCTGTGCTATTGTGAACAGTGCTG +CAATAAACATCCATGTGCATGTGTCTTTATAGTAGAATGATTTATAATCCTTTGGGTATA +TACCCAGTAATGGGATGGCTGGGTCAAATGGTATTTCTGGTTCTAGGTCCTTGAGGAATC +GCCACACTGTCTTCCACAATGGTTGAACTAATTTACACTCCCACCAACAGTGTAATAGCC +TTCCTATTTCTCCACATCCTCTCCAGCATCTGTTGTTTCCTGACTTCTTAATGATTGCCA +TTCTAACTGGCCTGAGATGTTATCTAATTGGGGTTTTCATTTGCATTTCTCTAATGACCA +GTGATGATTAGCTTTTTTTTCATATGTTTGTTGGCCGCATAAATGTCTTCTTTTGAGAAG +TGTCTGTTTATATACTTCACCCACTTTTTGATGGGGTTATTTTTTTTTCTTGTAAATTTG +TTTAAGTTCTTTGTAAATTCTAGATATTAGCTCTTTAATAGATGGATAGATAGATAGCAA +ATATTTTCTCCCATTCTGTAGGTTGCCTGTTCACTCTGATGATAGTTTCTTTTGCTGTGC +AGAAGCTCTTTAGTTTAATTAGATCCCATTTGTCTATTTTGGCTTTTGTTGCCATTGCTT +TTGGTGTTTAGGTCATGAAGTCTTTGCCCATGCCTATATCCAGAACTTTTTATTGTTCTG +TTTTTCATCTTAGGCTTTGTTTTCATCAGCTGATTATTTTTCATGCCTCCTGTACCTATG +TTGTTATTTAATATTTTATTAATTAATTTACTTAACTATTTATTTTGTGAGCAAGCTTAT +CCCCTTTCCTGGACTACTGCTGGAAACAAACATTCAAGCACTCATTGGTGCTAAAGGCAA +AGGCCTCTTCAGTCTAGGCTGTGAGAAGTAGAAAGCACCACTATGATATTTCATTTGCCT +AATTATTGTTTCTTTAATCACATCAGATTGATTACTTAAACTACTACTATCCTATAGAAA +TATAATGTGTCTATATAAGTAATTTTAAATTTAACAAAGGTAAAATGAAACAGGTAAAAT +AATTTTAATATGTTTTATTTAACCTAATATATTTAAAATATTATCATTTCAATATGCATC +AGTATAAAGTTACTAGCGAGGTATTCTTACATTGTTTTCTTTTTGTACTAAGTCTTCAAA +ATCCAATGTGTAATTTATACTTACATCACATCTCATTTGGACTAGCTACATTTCAAGTGT +TCAGTACCTTCATGTGGCTCATGGCTCCCATATGGGACAACACAGGGCTGAACTGTTAAC +ATGACAAAAGAGTGGAAGTGGAGGCCAGGCGTGGCAGCTCATGCCTGTAATCCCAGCACT +TTGGGAGGCCAAGGCAGGCAGATCACCTGAGGTCAGGAGTTCAAAACTAGCCTGGCCAAG +ATGGTGAAACCCTGCCTCTACTAAAAATAGAAAAATTAGCTGGGCATGGTGGCACGTGCC +TGTAATCCCAGCTACTCAGGAGGCTGAGGCCGGAGAATCGCTTGAACCTGGGAGGTGGAG +GTTGCAGTGAGCCGAGATCACGCCCTTGCGCTCCAGCCTGGGAGACAGAACAAGACTCCA +TCGCAAAAAAAAAAAAAAGTGAAAGTGTAAATGGAAAAAAATAAATCTATATTGCCAATT +ATATTTCAATTTCTATAAGTGACTTGGTTGTTTTCTAATGAATTAGCTACTTTAATCTAT +CTGGGAGTGAGACATAGTCTTCATTGTATACCTGGCCAACAGGGGCTCCGAAAGGTAGAT +CATTTCTCAAACTTGATTCAGCTCATAAAGTCAAAAGTGTGGATTCAGTCTTGTGTTTGG +TCTTTTCTCACCTGAATTTTAATTACTCTGAATTCTGTGTTAGCTGGCAAGGCTGGGAGA +ATTGTGTTCTTTCTAATTTGTCCGTAGCTGCTACAACAGGTTTGATACTAAGAGATAGGT +ATGATAGTACAATCAGAGCCATTTGGGGGATGTTTTTATTTTGTCCACAAGAATAACTTG +GGACCTTTTACAGTTACACCATAAATAGTAAAATTGCATTTTGCATTTAGATCTGTAAGA +GAATGGCTTATTCTGTGTATTCTATGAAGAGATTAATTTTCATGCCTCCATTTTATTAAC +TGAGTGCTGACCTATTAGGTGACACACTGGACCCTACAAAGGAGGCTTTTATAAGATGGC +AAGCTGGGAAGATCATACATAAGAATAGCAATGATAGTGATGATGATGATGATGCTAGTA +ATTTCTGACTTGTATTGAGACCTTACTATGTTCTAGGCACCATGTCAAGCTCTTTTTAAA +TATTAGTTCATTTAGTCCTCACAAAAACACTATGAAATGTGTAAAATTATTATTCATCTT +GCATAGATGAGAAACTGAGACACAAAGAATTCACAGAGGGCTGGGATGCCAACTCTGAGA +AAAGACAGTTTTGTGATCTTATTCATTATAGGAAAGACATATTTCCCAATAGAAAAATTA +TTTGTTCCAGTTGTCCAGACTTGAAAATGATGACTCCATCTTTGTCCAGTGCTAATGCTC +CCATTCATCACTAGTTTCCATCTAACAAGGCTTATTTTTAACTTATTTCTAACTTCCTCC +TATTTTTACTGGTTTCTCTCTGTCTTCTAACACTTAGCCCTGTTCTCACTTCTACGTAAG +CTGTTTTCCACTTGGCATTTGTCCTTGGCCTTCTAATCTCTAGTAACTACGTTGGGGAGG +GTAACATACATTGTTCCTTCCTTGGGTTGAAATTCCCAGCTTTAGCCTCTTGTCAAAAAT +ATTGTTGGGCCCACTTAGGTCCTTCAGAATATTCACAGCTCATGTCTTTGCCCACTTTTA +ATAGTGTTTTTTTTTTTCTTGTAAATTCATCTAAGTTCCTTATAGATGCTGTATTAACCT +TTGTCAGATGCATAGTTTGCAAATATTCTCTCCCATTCTGTATCAACTCTACTGATAGCT +TCTTTGCTGTGCAGAAGCTCTTAAGTTTAATTAGATCCTGTTTGTCAATTTTTGCTTTTG +TCGAGATTGTTTTTGGCATATTCATCATGAAATCTTTGCCTGTTCCTATGTCCAGAATGT +TATTGCCTAGGTTGCTTCCAGGGTTTTTATAGTTTTGGGTTTTACATTTAAGTCTTTAAT +CCATCTTGAGTTGATTTTTGTGTATGGTGTAAGGAAGGGGTCCAGTTTCAATCTTCTGCA +TATGGCTAGCCAGTTATGCCAGCACAGTTTATTCAATAGGGAGTCCTTTCCCCATTGCTT +GTTTTTGTCAGCTGTGGCAAAGATCAGATGGTTGTAGGTGTGTGGCCTTATTTCTGGGCT +CTCTATTCTGTTCCATTGGTCTCTGTGTCTTTTTCTGCACCAGTGCCATACTGTTTTGGT +TACTGTAGCCCTGTAGTATAGTGTGAAGTCAAGTAGTGTGATGCCTCCAGATTCGTTATT +TTTGCTTAGGTTTGCTTTGGCTATTTAGGCTGTTCTTTTGGTTCCAAATGAATTTTAGAA +TGTTTTTTCTAATTCTGTGAAATAATGTCACTGGTAGTTTGATAGAAATAGCACTGCATC +TGTAAATAGTCTTGGGCAATATGGCCATTTTAATAATATTGAATCTTCCTATTCATAAGT +ATGAATGTTTTTCCACTTCTTTGATCAATTTGTAATTCTCATTGTTGAGATCCTTCACCT +CTCTGGTTAGCTGTATTTCTAGGCATTTTATTCTTTTCTTTTTGTGGAAATTGTGCATGG +GATTGCGTACCTGATTGGGCTCTTTGCTTGACTGTTGTTGGCTTATCACCATCATTTTCA +CCGTCTTCCAGACATTACACGTTGATGTATTATTGGTTCTTTCTTTTCCTTTGTTCTCTA +CTTCCAGTCAAACTCTTGCTGAATCTTCCATCATCTTGCTCTTCATCAGTCCCTTGTTCT +CACAACTAGATAATTAAAGCTAAATTCCTAACGGGCTTTCCTACCTCCAATCTATCCTCC +TTTCATTTTATACTGCACTGCATTTATCCACTATTTCTTAGGATGTCTCAGCCTGTGTCT +TAGGCTTCAGTGGAAATAGAGTCACCAACTCTAGGCCAGTTCTGGACCCTTTCTGGCTCA +CAATAGGGTCTCTTGATTTATAAACTCATGTTTGAGAATTAGGCAATATCTCTGTAAATA +AAGAGAGAAGTCAAAGATAATGCTTCATCTTTGCTAGATATTCCAAAAGTGACTCATGCA +GCAGATACAGCATTTAATTAGAAGACATACAATTGATTCTTTAATTTTTGAGCAGTTTCA +TATTTTGTTAAACAGAAGAATTAATTATAAAATAGTTTGTTTTACATTCACTTGTTTGCT +CATCTTTTATTGACTATCTACTCTCTGCCAGGAATTTTGAAGGATACAAAAATGAATAAG +ATGTGTCCAGGATTCTTTGTATGCCCACTACTGGCATTCTTACCAAATCTTGCTTTTGAT +TCTGCTTCATCGCTTGTTTGAGATGACTTCCAACATTGGACTCAACTTGAACTTTTTGTT +TTCTCTAGAAAGGATTCTGGAAAACTAATGAAGAAGGTTAACCAAGTATGAGACATCTGC +TATAAAAACCATTAATGGCTTTCAGCTCTCCAATTAATCAAACCCAACATTTCTACCCAG +CTTTTAATGCTCTCTAAAATCAACTTCTTGTTTTATATTTAAACCTATCTCCTACTACCT +CACAGCCTTACTCCTGGCCTCCCAAATATTAGGTTTGTTTTACATCCTTACAGACAAACT +CCCACCATTTCTTTTAACTAGGTTCCATGACATTTTGGACCTTAGTTTATTCATAGGTAA +ACCTAGGATAATACCCGACTCCTAGGGAACCATGAAAATTAAATGAAATGACAAATAGAA +AGCCCCTTTTAAAATTCCTAACCATAAGGGTGTTGAATGGTCATTGATTCCTTCTCCATT +TCAAAAAAGAGAATGTGGTTCACTTATGCAAATATGACACATTTTTCAAAACCAAGACTC +TGCCTCCTCAACATTTTTCATAATGACTTTCTGACTTTCATCTCTCTAACAATAGATTTT +TGCACATGTTGTCTTCACATTAGAATATTACTAACTGCTATTTTATTTCCATTTATCAAA +GTAGCCCTCTATAATACATTTTCTTAGTTTCAAAATGATACAGCTTTCTCAATCTTGTCT +TGCTAGTATATTGTAGCTAATAGGGAAGAATCAGCCTTATTTTGAACTAACCTACAACAT +CTAACATAGTGCTTGGCACATGACAGATGCTGAATATATTATATAATTTAATTTACTTTG +GTTCATGATGGTGGATCTGATAGATCAACAGCTATTCCAGTCTTACAGATAAGTGAAGAT +CATATTTATTGTGGGTAACACACCAAGAGATTTATGTGTCTGCTGATCTGAATAAAATAT +ACTTGTATTTTAATGAAACATTGGCATGTTATATATCAGGTATGAACTTGGACAAGCACA +ATTTTGAAAATTGGATTTAGAGAATATATATCTCAAGATTGCAAATGCTGAAAATAGAAA +ATCTTGGGGGGGAAAGAACAATGAAATTAATTGAAAAGAGGGAATAAGAAGATAGAGTTG +TTTTAGTTCAGTGGGCCCTGAAATACACTACCCATGTCCCAAACAGTGACAAGACCAGGT +TTAATGAACTTGTTGCCTCTTCAGTTCTGAGGGCCTTCTTTAAAAAAAAAATAAATCCAA +GACTAGCAATACAAACCTACATAAAAGGCCTGAGAAGCAGCTTGTGTAATGGAGTGTCTC +TGAGGGGTAAGTTTCATTAGCTTATAATGAATCAACCTCGGAACTCAGGTAGAATTATCA +GAATCTCTGTAATTAGCCACTGAAGCTGTGGCAAATAAACAAAGAGCATATCCCTCTTCT +CCAGCACAATAAAGTTTTGTTCCTTGTTCTACACCTATTTCTACCTTATATCTGACAATT +TTTTCAAGACTTTTCCCGACTGAGACACCTCCATGCATGACCATTGTAAATTTACAACCG +TGCCATTCAGTGCTTTTTCCATCAGTTTGTATTCAGCTCTCCATAATTGCTCAAGAACAA +ATACATTCTTCATGTTCAGCTCCTCCTGAGAACGCAGAAGGATGCTGTGGATTGGATAAA +TAAGGCAAGATAGGATTAGGGAAAGAGATGGTCAGCTCTGAAGCCACTAGGAGAAATACT +TCTTTGACTGATGGAGAAAAATGAAGAAAAAATGAACAGCAAGAAAGAACTGGGACATAA +TTGCAGCTCATGCCATTTGTCTTTGTCCTCTAACCTCACCTGAAACCCCAGTAACTATAT +CAATCACACAAATAGGCACTCTGTACTTGGAGTTGGACTTTTTTTTTCTACATTGCTTAT +TACATTATACAAATTCCATATACAACTCATTGAAATGGTTAGTTCTTTAAGCTTGATTAT +GTCAATTCCCAGTGACCAACCTATGAGCAAATCCATTCCATCTTATCCCACACTTCCAAA +CCTACCTAATTTATCCTATCTTCTTCCTGGCTTTTTGTCTTTTCTGCTTTTCTTACTTTT +CTTGAATCATTAAAAATGTTTGCACACTTGTTATGTGTCAGTTCTTCATCTCAAAGAATT +ATAGTAGGAGAGATACAAAAAAAATCACAATTTTATATGATGAATTGCATGATGGTGCAT +ATATACACACTCATAGGCTGATATGACCGACTTATGAGGTGTGAACACCACAAGTGAGTG +AAAAACTAAAACGTATGTTCAGAGACTTGCAGAGGCTATTCTTGAAGAATCTTACATGCT +ATGCTAAAGAATTTGAATGGTACGCTCGAAGGGTAGTGAGAAATCCATTCAATAGCTTTA +AAAGGGAACATGATACAGTCAGATTTCGGTTGTAGAAAGATCACTTTAGCAGCTATGCAG +AAAATAGGTTATAAGATGGCAATACTATATGGCGGGAGATAATTTTGAGCCTATTAATGA +TAATTCAGAAGAAATATATTTTTAAAAAATTAACGAAGGCAATGGCAATATGAATGAAGC +TGCGGTGAAAAATTTCATCTGTAGACTTCTTTGATAAACAGATTGATGAAGAATAAGGAA +TATAAGATGACTCCAACCTTTCCTATTTAGGAAATGGAAGAATTTGGTATTACTCTCTGA +GTCAAGAAGCACAGGTGGGGGAGTAGGTTTAATGCTAACTACTAATTATTGAGCACTGAC +TACACCCAAGGAGATGCTAAGCACTTAACGTGCATTATATAATTGTATCTCAAATTAGCA +TCATTAATTATATTGAATTTCAAGAAGTCAAGGCTCACAATGTGAAGAAGGTTGTCAAAA +ATTACACTGTAGCTAAGTGGTAGAGCTGGAATTCAAACTTAGGAAGATCTGACCCAGAGC +CATGCCTCTTAACAAACACTATACCAGTGCGAATTGAAGTGTGGGCCAGAGGCTACTTGC +ATGCAGATGATCTAAGGTACTTTCTAAATACAGGTTCCTGGGTCCAACAGGAACCAGTTT +ATTCAAACAGAATTCCTGGTGGGTGGGGACTGGACTTACCAGGCATTTTTTATGCACCTT +AATCTTTACATACCACTGCAATGCATAGTAATATACTACTGCTTGGTAGAAAGATGATAA +CAAATTCACTTTTTTATATGAAAATCTTTAGCATTTTTTCCAAATCTCACATTTATAGAA +AAGATGCATACAATAGAAATACCTTTTTTTTTCCTGAGCCATTTGACTGTAAGTTGTCAA +CCTGATGCTCATAGCCTGCTAATACTTTAATACCTCCTACAAATAAAGGCATTCTCCTAC +ATAGTTACAATTTGACAGTCAAAGTCAGGAAATTAATATGGATCCTTTAGTAGCATATAA +TCTTCAGACTCCTGACCAGTGTCACCAGTTGTCCCAGTAATATATTTTGTAGCAAAATGA +TCTACTTTGGGGGGCATTAGTTGTCAGATCCCTTTAGTCTCCATCAGTCTGAAATTGTTT +CTCAAAATTTTTATGATATGGTTAGATACTACAGGGCAGTTATTTTATAGAATACCCCTC +AATTGAGATTTGTCTGGTATTTCCTCATGATTAGATTCTGATTATGCATCTTTGGCAGGA +ATATTTCCAAGTGATACCTGCCTCGTTTGGACCCACCCAATAGCTTTAGGAGTGAATTAT +TCAGGAAGGAAGAGGGAGGGAAAGAGGAAAAGTTAACTTTTCAGTATGTTGAGTTTGAAA +TTCTTGTGGAGCAGTTAGATGATGTCTAATAAGTACTTGAATAGATGGATCTGAGGTTCA +CCTGAGAAATCATATCTGAAGACAGAATTTTAGAGTCATCGAAGTGTAAGTGATAGTTGA +AGCTGTAAATGGGAATTAACTCAATAAAGGACTTTATGTAGAGCTAGGAGGGAAGAGGCC +AAAGGGTGAGAAGACCACGGGTGCACATTGATTTTAAGAATCTAAAATAAGAAGGAAAAC +AGGCAAAACAAAGTGAGGAGGAGTAGATGATGGAGAGGTTAAAAAAAATAGTGAAACAGG +ATTAGGAAAACTAATGGAGATGAAGGTTGCAGTCCTAAATTAATCCCTCCTGTTGATGTT +TTCTTCAAACTGTCCTTGCATTTACTCTTCTTTACTGCAACTGGACTTTCACTGATAATG +TGGATTCTTTTATAATTCTTTTAAGTGGAATCTGCTCCTCTCATGTTATTAAATTCACTA +TTCCAAAAAAAATTGATATACCATTTGTTTATCTTTTATCTCTGCAAGCCCTTTGTTTCC +CCACAGTAGACATGATATTCTTTCTTATCATAAATAAGTGATCTACTGAAAAGTTTATTT +TCTCCCAAACCCAAATTTTAAAAAATTATTCTTTAGTAAAGTCGACGTTTTTCCTTATTT +TAACCCCTCAGGTGACCTCGAATCCTCCCATTCAAATCTGCTCTTTAAAAAATGAAGGCC +AGGTGTGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGCTGGTCAT +GAGTTCAGGAGATCGAGACCATCCTGGCCAACATAGTGAAACCCCGTCTCTACTAAAAAT +AGATTAGCTGGGTGTGGTGGCACATGCCTGTATTCCCAGCTACTCGGGAGGCTGAGGCAG +GCGAATCGCTTGAACCCGGGAGGCAGAGGTTGCAGTGAGCCAAGATCGCACCACTGCACT +CCAGCCTGGGCAAAGAGGGAGAATCCGTCTCAATAAATAAATAAATAAATAAATAAATAA +ATAAATAAATAAATAAATAAAAATGAGATACACACCTAGTTAACAGCTGGTTTGTCAGGT +ATTGGTGAATAACATCCTTGGGCCTAGTAAATGAGTGAGTATTGCCTACATATATGAGTT +AACATAGGACACTGTCCTAGGTTTTTGCCCTTTTATCCCTACACTTTCTCCCCCATTATT +CTTATCTATTCTCACTTTTAAATACCTCTGTAAGCTAATGTCTCATAAATATATGATCTG +CAGCCTGGCCTCTCCGCTGAGGTCTAAACGCACATTTACTTGAAGATCTCAATGTATAGA +AAGGTGGTATAACATAGTGGTTGAGAACATTGACTGTTAACTCATTGACTGGACTCGTGT +CCTGACTTTTGAGACTTACTAGCTCAAATTTATTAAATTTAGCAAGTAATAACTTAGCAA +GTTACTTAAATGATTTGTACTTCGATTGCGTTATCTGTAAACAAAGTGAATAACAATATC +TCCCTCACGGTGTTGTTATGAAGAAATGAGCAAAACATTTAGAAGAGTGTTGAACACATC +CTAAGCATCACATATGCTTACTTCTATTATGTCTCATAAGAATATCAAATTTAACATTTC +CAGTCTTGAACTCTTGCTCGCTCCACAACTCCAAACCTGGCCTTCCAACTCAGTAAAAAG +TACCACCAAACACCTACTTGGTCACTCCAGAAGCCTGCTTTTTATCACTTCTTGTTCTTC +ATCTTTACCTCATATCTAGACCTGTCATAAATATTAAGGAGGTATATAAAGCTCCATTGA +TTGTTCTTTAAAATATACCTTCCATCCATCCTCTTCTGTCCATTTCCACTCCTCGCACCC +CGTATCAAGCCACCAACATGCCTCATTCAGTGACTCTAGTAAACCTCCTACGGGTTGCTC +TGCTTCTGCTGCCTACCCCCTTAGGATCCACTATCCACACAGAAGGCAAAAAGAACATTG +AAAATGTAAATCAAATTGTGGCAGGCCTCCCCTTACAACACATCAGTTCTTCCATCTCAC +ATACTCTATTTCCTTCAGGCTCATGCATGATCTCCTCTGTGACTTCTTCCCCAGCCTCAT +CCCCTTCACTTCCCTCTAGCTCATTACATTCCAGGAACAATCACTTTGTATCAGTTCCGT +GAAACCCCAAGTTCTACCTCAACTTAGGGCCTGGCATTTGTTACTCCCTTTGCCAAGAAT +GATCTCCCTCCCAGCCTTGAGTCCCAAGGTGTAGTCTTTCTTACTTTCTGGGTCTCAACT +TATTTTTCCTTCATAGAACTCTGTGATTTCCTTTTGCAGTTTATATGTAATTATATAATT +GTTTACTTTTGTAGGGGCTGCCTTTCCAACTAACCTGTAAATGAACTTAGTCTATATAGG +GACTCAGCTGTTTAATTTACCACACTATACCCAGTATACAGCACAGTGTCTGTCATATCC +AATAACTATTTATTGAATGAATGAATCAGTGAGTAAGTAAATAAAAGATAGGAATATAGA +TAAAGTACTCTTTCAGGTTCTGGAGAGCTTTCTTGGAAGCTGGAGATCAACAAAAGTTCA +CTTCTTTTTTCAGGAAAGCCATGAAAATTAAGATGTCATTAATAAAGAGGTGTTTCCCTA +ACGCCTAAGTTGTGAGTGCTTGCTTTAAAAATACCAGTTCCTGTGCCTGTACTCAGAACC +AAAAATTTAGAATTTCTGAAGCTGGAGCCTAGGAAGTAACATTGCCCTTATGCCCTAGGT +GATTCCAATGCACACCAGATGCTGTTATCATGAGAATAAAATATATTTCTAAACAAAGCA +ATCGGTGTTCCAGGTGCTATCTTCTACCTAGAAGTGCTGAATATGGAGACACCACCCAGA +TGGCCATAGGGTGGAGTGAAGCAAATATTTTCCACTAGGAATTTTATGTCAGGATGGTGA +AACTCACAATTCTGAGACTTAAAATGACTAGTTTTTCTTCAGCCACCCTGTGTTGGTTTG +GATGAAGTAGAAAATTCAAGATGGTGGTGGGATACAGTAAATTATTCCCAAGCCTCCTAG +ACTTCTCTTTCCTTCTTCATACTCTCCTTTGGTGGGTTTGAGCACATACCTCCAAATCTG +CCCCATGCATGAAATGTCTTTGTGGCTTTGTTTCCCTACAAATGCTTGCAAATTGTTTTT +GCATTTTACCCCATAAAATATCTGTTTTTTATATAAAATTACATTGAATTATGTACCAAG +AGATGAAACTGATGCTCCAGGAAATGGCATTGTGTTGTTGATGACTCAGTTTACCCTCAA +GGACACCTAATCCTCTCTTTAGGCGCATGAGCAACCCATTTGAGAAACAGGTGATTGTTG +CCTGTATATATCTTATCTCCACACTAAACTGCAAATACCTTCTTGTATTATGTTATGTTC +TTCACAATGTTTTCAACACAGTAGATATCCAATAAATAGCTAACGAATTTGGAACACAAG +AGTTTGAAAGAAATAAGGAATCTGAGAAAGCAGGATAGACCTGCAAGAAGCCAGATGCTA +TTGGAAGTGCCACCGTAGGAAGGTCCTGCCTGCCTCTCAAGATCAAGCGATCACTTCAGC +AGAGAATGCTTTTGGTCTTAACATAGTCTCTCCAAACTCATGGCCTTCAGTAAATGGACT +TCAAAGAGGTCTTGGACTTGCATACTCATGCGGAGAAGAAAAAAACTTTTCGAACATCAA +ATTAGAGCTTTCAGGATCAAAATGCTCAAACTATCTCTCATGATACCTGATGGAATCAGG +ACTCAGAACATTCCCACCTCCATGATATTTTAACTCCCCTTGTTTTTCTCAAGTTGCATT +AACTTAAATGCTAACAGCCTACTTTAGCTTTTTTGTAATTAACGTTTTTAAAATCTGTGC +TCTGATCTAATTCAAGACCATCTATAAGGTGAAATACTCTATGAAACCCTTATTAGTGAT +TTTTTAAAGAAAATATTTTTTAAAAAGCAACCTCCCTACCACTTACAATAATGTTACCTC +AGTACACAGCTTTTCTGCAGACATTCATATTCAACCCCACTTGATTCTGTTAGTATTTAT +TTCTTGTCCAGTACATGCAAAGTAATAATTGACATTGCTATATAGGAATCTGTTTTTGTG +GCTTATGGCTTGGGAATTTATTTGGCTCCTTCTTAAAAACTTGGTCTTCTTGACCCCTCA +GCCTTCACCAGTTTGAAAATTCCAACCATAATCCTCTGTGGGGATTTACACAGGTGTCTA +TTATTGCCCATAATCTGTGATAGGGCTTCCAGTATCCTTGTTGCAGAAAGGTTAAGCCCT +CCCGTCTTTATTCCTGAGTAAAAAAGTCCACAGGGTTTTAGTATTGTCAGGGAGCAGATT +GAAACAAGCTGCAACTTCAATCAGGCCCTAAGCTGGTGTCTATGCCAGCGGGGAATCTCT +GTGATGAACAAAGGATTCCATTAGAAAACGGAGCAGTTAGTTTTTAACTCCAGAGTTATA +CAAAAACAAAACTCTTTATCCTCTACTATTCTTAGGGTGGCCATATTTTCCAAACCAAAA +TTTGAGACTCATGTTCTGACAGATGCATAGGTGCTTTTGTCACAACAGTTTCAGACTATC +TAATGTTGGGACAGTCCCATAGTATTTAGGATGTAGTAGTCCCACTTTATCCACAGTTTT +AATTCCCATAATTTCAGTTATCCCACAGTCTGAAAATATTTAATGGAAAATTCCAGAGAT +AAAATAATTCACAAGTTTTAAATTGTGTGCCTCTATAAGTAGTTTGATAAAATCTCACAC +CACTTAGACCTGTCCCGCCTGGGACATGACCCATCTTTTTGTCCAGAAGCTCCACACTCT +GGATGTTACCCACCCACTAGTCAGTAGCCATCTCGGTTATCAGGTCCATTGTCATAGTAT +CACACTGCTTGTATTCAAAGAACCCTTATTTTATTGAATAATGGCCCTAAAGCACAGAGG +TAGTGTTGCTGGCAATTTGGATATGCCAAAGAGAAGCTGTAAAGTGTTTCCTTTGAAAAG +GAAAAAGTTCTCAACAAGGAAAGAAAAAAAATCATATTGAGGTTGCTAACAGCTATGGTA +AGAACAAATCTATCTGTGAAATTGCAAAAAAAAAAAAGACAAAGAAATTTGTGCCGGTTT +TGCTGTCACACCTCAAACTGCAAAAGTTATGGCCACAGTGTGTGATAAGTGCTTAGTTAA +GAGGGAAGAGGCATTACATTTGTGAGTGGAAAACATGAACAGAAACGTTTCGACTGACAG +CGATCAGATTTCATACTATCCTCACTTTCATGCATCCAATGGGGGGTCTTGGAACATTTC +CCCAGAGAATAAAGGGGGACTGCTCTGTACTGTTGCTGTATGCATACCACATGTTGGTAC +CCAGCATACCAGTTAACAAGGAAGCTTACAAAATGAGATTGCACTACATGGCCATTAGTA +GAGATCACTGCCCTTTTTGTCCTGAGGGCCAGTGGGCAACTGGAAACATATGGCCTTGTG +GACCTTCCTGTCTGAAGATATACAGTTTGTCTCTAGAATTGTGGTCATCAGGGCTTGTTA +GTATGTTTGTGGTGCTGATCTTTATCTTTCAGTCTTCTGAATCTGAAAGACATGTCCACT +ATCTTAGATTGTTCTTACCTCTGGTACTGACTTGTCTCTGCCTCTCCCCAATGCCAGTAA +CTAAGCTATAAGACCTGAAGGGGGCACCTCAGCGTGACCTGTGAACATCAGCTCCCAGAC +TCAGAATAGTCTAAGTGTCTTCAGAAAAGTCACAAAGAAGGGGCCTTCCCATGCTATAGC +CAAGCAAGAATTTGGGAGCAGAAGGACTTGAGGCAAGGAGGAGTGGCCGGGAAGTGGCAA +AAAGGAACTGGGATGGGGAGTCCCTCCACCAAAAATTATACCTCTGATATAAAGGAGTCA +GTCACTAGCCTCCCAGAAGCTTTCTAGACGATGCCCCAAACTTGCAGTTAAAGCATGGTT +CTCATGGTTTCAATCTCTGAGAAACGAATAGTAGGCTCTGCAACCAATTTCTACACCCTT +TAAAGGCCTTGCGTTGGAAACACCCTAATGGTATCTATCTCAGTCACAGCAGGAACAGGT +TGGGAGTGCCATTCCAGAATGCTGCTTCTTGCCTTTGTGTCTTTTTTGACTGTCACCAAT +AAAACAAGCAAGGATAAGCCAGATGCAAATGGGTGCAGGACATCTCTGTGTCATTCTTTT +TTCATGATTCGTTTAAGTGTTAACCCAAACGCGTCTCACATTCACTTGTGTACATGTCTG +CTTGGCATGTAGCTTACAGTTCAGTGGCAAATCTCGCGTAAGAATTCTCTTCATTTTCAA +CTGTTGTTTCCAATAGTTTGCCCATAGGTAAAGCTTGGAAAGGCAAAGTCAAAATGATAG +CAACCGGAAGTGTTACATTAATATCGCTTACCTGAGGTTTATATATATATATATATATAA +AACTCTGAAGGGCTTAGCAGATCTTAGGTGAAAGGATGTTCTTTTCAAAGTGTCACTTTG +CCAGAAGAAAGGAAGAAAGACACCTTCCATCAATAGAAACAGTAAAAGCATGCCTCAAAT +TGTATTTATCTCTCTAAATTCTGAAAGCGTATTAAGGAAGAATAGCAATATTCCACTTTG +GCTACAAATTGCTAATTAATAACTACAATTCTCCCAGAGGTAAAATATTAACATTTTAAA +AATGAAATTAAACATCACAATCTTCTTCTAATTGTTACAAAAATATTTAGCAGCAATAGC +TGTTTAATTATTTAGGCATTTGTTAGTGGTGTAAATATTATCAGCACAGTCATAAATATT +TTCTGCTTTGTCCACAATCAGCTAAGGATATGTTGCTTGTGGGACTTAAATTAAGATCTA +TTTAAGGCTGCCTGCTGGCCACAAAATAATTACTTACACTTCCTGATGCCTGAATCTGTT +AGATATAGCAGCAAGAAGTGTACTTTGTTTTTGTAAGTCAGAAAAAGTTGCATTTTCTTA +TATAAATTTCATTGTTGATGTTATTAAAGAGGATTAGGGTGGGGTTGAAGTAGCTGAAAA +TTTAATTAATCTAATCCCTTTAACAGGAATTATTTTCATATTGATAATTCTCTGTAATAA +CAGTATTACAGATCACGCCCTGTGAAATATTTACACTAAATATTGTAGCCTGTAATCTCT +CCTCCAGCTTTTTCTTTGGGGAAGGATAAGATTTACGGCTTCTTCACCTTTCATCTTTTT +TTTTTTTTTTTCCTTTCTCTCACCTGAAGTGCAGGGGACCAAAATGAAATCTTTTTTTTT +TCCTGCTTCCTCTTTTAATTTTCTGTCAATGTCATCATATCTCAGTAAGTTATGTTAATA +GCCATCAAATCACTAATCTCCTAAAAGAGCACGAGTGTTATGAAATAAGGAGAACAATTG +ATTTTTTCCCCTCTTTGGTATCTACAGTCATTTGGTGTAGATTCTCATTTGAAATGATTT +GTTTACCCATTGATTTCAATAAATTGTTATGCTGCTGAAAATATCACTAAGAGTAGAGTC +AAATGAAGGACGAAACTGTCATTCTGATCAACTTCCTCTGATCATCTCCGGTGTAAATTG +GGAATTGTTCTCAATCAGCTCAAATGTCATGTTATCAGGGAGACCTTCTCTGACTTCCCA +AAATAAAATTACAATCACCATTGCTTCCTTTAATTGGCTTTATTTTCTCCATACAAGTTG +TCATCGTGTAACATTATAACACATTATGCTTGTTTGTTTAGTGCCTGTCCCCCAACTAGG +ATGGAAGTGCCACAGGAAGCAAGGACTTGGATTTGTTTATTGCTGTATCTTGAGAGCCAA +GCTGAGTGCCTTAAATATGGCAATCAATAACACATTGTTGCATGTATGAATCTTTACTCT +CATTTTTTTAGGTGCCTGAAGCACCAGATCTGTGCCAAGCAATGAAGAACTTGATACAAA +TGTAGACATTTGCCCTGAGCTGGCTGATCCACTCAGCCTCAATGGAAGGGTGCCCACTGA +GAACAGACCTGGTGCTTTCTGTAGCTATGCCTTCATTAAAGAACTAAAACTGGGTTGTAT +AGTGCTGTTTGGCCTCCTCATGTTTACAATATCCAGTGATACAAAGCAGAGAATCTTTAA +GGATGCCCTCCAGGATACGACTTCTGTAGAATATGAACAGGAGTTACTAAACTAGAAAGA +GACTCCGTGGTCACATAAACCTATGTAACTAGGTATTATGTGAAGCTAAACAAGGTTCTT +AATTTCAAGGTATATCAGATTATGATAACATTCATTAGGACTCTCCAAGACAAGAAGATT +AGGCTGTGTTTCCTGAACTTATTTGGTCTTAGACATTTCCTCTCTACCAGCCAATCCTGT +TTCTACAACAGGGCTACAACAGAGGGAACTCCAGTGACTTGGGAATTCAGCAAGCCAGGG +AAGGGGTAAGAGGCACCAGTCTCATCACTGCCTCTTACTGACTTTATTATGTGACCTTGG +ACAAATTACTTAACACCTCTGTGCCTCAATTTCCTCTTCTGTAAGGTAGGGATGAAAAGG +ATTACCCAGGAAAATGTACGTAGTGTCCAGCACGCAAGTGCTAACTAAATGGTGGTTATT +GCCAAGACTTTATATTAAGTATAGGCATGAGAGCCTTTTACATAGATTTCTTCAACCATA +TTTTTTAAAATAGGTTTGTTAGTATTGACCAATTTCCAGAAGCAGCCTAATGTGTCATCT +CATGTGGCCCCAGTGCCCTATCCCTATCTGAGAAGCTCTGCACACCTGTGCTGAAGGCAA +ACAAATGTTATCTTTCAACACAACTTACTACAAACATCTGATAACTCACTTTGGTGGATC +CCACAGCGCCTTTCCCCTTGTTTCCATACCCCTGACCTCAGATGAAGACACTTTTTTCAG +GAGGAAGATGGCAGCATCCAAGTTAATGATAGTGCAGATGGCTACATGCTGACAGATTTT +GAAGTGACCATATTTTTTCAGTAAATTTCAAATGAAGGTGTGATTTGTGTAAATCTGACC +TCTTCCTGTAAAATGTGCATTTACATATATTTAGAATTTATAAATCCTGACAGATTCCAC +AATATTTATAGCCCTCCATAAAAAGCCTTTGCCAGTCTGTAGAGCTTTGCATTTGGCTCT +CTGGCATGCTTAAGAGAATTTAAATAATAATAAATTTGGTGATTTATTCCACCTGGAACA +GAAACTTATTTCCCCCCTCCCCTGGCTCATTTTGAAGGGGATACTATAAATAGTGCCACA +GACGCTGGGATCAGGACTAGGGAATTGAAATTTGAGAGAGAAGTACAGAAACATTTTCAT +TATCACTGATTCCTTGAGTGTATTTTTAAAACAGTTCTGTTCCTCAAATAATGTACCTTC +TCTTCTTTCTCCTGCCCTATCACAATTATACTTGAATCTCCAAAACCTGTTGCCAACTTT +AGGATTCGGTTACATTAATGGGAAAGAGAGAGTGAGAGTATTAGCTGACTAGGTAGGAGA +AAGTTGCCTCTAGGGAGACCAAAGCAATTCTCCCATGTTCATCTTATATTTCATAGGAGT +CAGCTAGTAACTGAGTGTCAGTGTCTAAAGTGTAAATTCATTATCTGAGACCTCGCTCCT +GTATCCTACAGGTATGATGAAAAGCTCACAGTATATGGAAAAAAAAAAAAAGGAAAGAAA +GAAAGAAACCTAATTGTAATTACAAAAGGAAGCCCAAGGACAATGTCCGAGGATCAATTC +TTTTCACCCAGCCATGCTCATAATAACTGAGTACAGAATAAGAAACACCTGAATAGTCAA +GTCCTAATGATACTACTTGTTTTCTTAAAAACAAAATCAACAAAAATCTGGTAACTTGTC +ATTTGCCATGGAATCTACTGATGAAAGCTGAGAGTAGCCATTTAGTGTAGCATAAGCAGT +GTTGTAACTTGTAATATAACTAGGAGATTTATTTCTAGCTTCTTGTTTGAATGTCTGTAA +AGGAAGTAGCATTTGTTAAAGGTAGAATAATAATAACTAACATCCATGAAGAACTGCCTG +TGGGCAGGCACAGAGTAACAAACACATCAAGTGGCTGTGGTTTGATGTGCAACAGCCTCC +TAACTGAGTAGTACGTTTTCTTGTCCTGATAACTTGGAGCACACTCCCAGCCCCAAGACT +TTCCTGAACAATCCTTTTATCTCTACCTAATAGGCTGGCAGGTATTTGGACCAAGCCCCA +GAGCCTTTAGGGTACCACATTTTAATAATTGGTGGTGAACAAAGTAAACGTTGTAAAACC +AGACATTATGAAGCAAGGACCCAGTTAAGTATGACGGATTTCAGGGAAAGCCAAAAAAAA +AGGCTGAATGTTGTATGGGGGTATTGTCTCCCCTACAGAACACAGGTATCTATGGTTCAT +GGCTCATTCTAAAGCTTTGCTTGAAAAATGACTTTTTAAAGAAGTGTACTCTTAAAGAAT +GTCCTTCAGGCAGGGAGGAATTTCCCTTGCTTTTCTATAGCATCTTTGTAAGAGGAAGCG +GAGGTATTGAGCTGTTAGACAGTTGCTCGGTGCCTTCGTGCTTCTGTGACCACATTATGG +GTCTAACACATATGGGATAAATAAACTGTTTTCATTTCTTAAAGCACATGGAAGGAAACA +AGACAAGAAAATTACCATATTGCTTTTTTTTTTTAAAAGCTATTAAAGAGGAGAATCCAG +TTAGGGCAAATAAAAATGATTACTGAAAACAGATTTTTTTTTTCCTTTTCTAGCCTCTTA +CTGAGCAACAGCAATATGGCAAGACTTGTGGCAAACCAGTGTTTTGATGCACGCTCTTTT +GTTCTTCTTCCATAGGGCAATCCCTACATGTGCAATAATGAGTGTGATGCGAGTACCCCT +GAGCTGGCACACCCCCCTGAGCTGATGTTTGATTTTGAAGGAAGACATCCCTCCACATTT +TGGCAGTCTGCCACTTGGAAGGAGTATCCCAAGCCTCTCCAGGTTAACATCACTCTGTCT +TGGAGCAAAACCATTGAGCTAACAGACAACATAGTTATTACCTTTGAATCTGGGCGTCCA +GACCAAATGATCCTGGAGAAGTCTCTCGATTATGGACGAACATGGCAGCCCTATCAGTAT +TATGCCACAGACTGCTTAGATGCTTTTCACATGGATCCTAAATCCGTGAAGGATTTATCA +CAGCATACGGTCTTAGAAATCATTTGCACAGAAGAGTACTCAACAGGGTATACAACAAAT +AGCAAAATAATCCACTTTGAAATCAAAGACAGGTTCGCGTTTTTTGCTGGACCTCGCCTA +CGCAATATGGCTTCCCTCTACGGACAGCTGGATACAACCAAGAAACTCAGAGATTTCTTT +ACAGTCACAGACCTGAGGATAAGGCTGTTAAGACCAGCCGTTGGGGAAATATTTGTAGAT +GAGCTACACTTGGCACGCTACTTTTACGCGATCTCAGACATAAAGGTGCGAGGAAGGTAA +GAGAAAATCTGTCTGCCTTCAATGGGAACGGGTGTGTCCAAAGAAAATGCCAGAGTGTCT +CACAGCTGTAAAGTGACATTTGTCAATTTCTACTGCAACGTTTTCTTCAGGAACTCCACT +GTAGAAGTAGGTTCTGAAGGCATTCTGAGATCCCTCATCCTCAGCAGTAATTTGTAATCC +CAAACTTGCTGTCCCTGAACCTGGCATGATTCTTCAGAATTTAAATAAAAGTGAATTTTA +AAAAGTAACTCCCTGAGTCGGGAGGTCCTTTAGGTCTTTAAGGCAATGAAGCCAGGGGAA +GCAAAACCATTTGCCCTATAACGAACTGAAAAACTAGAAATACAACATACCATTGTTTAC +AAATGCAAAGCAGGGATTCAACATGGTACAGCAGTCAATTTATGTTTTGTGTAATATTGC +ACAAAAAAATCTGGAAACTAGAGTTATGTTTCTTTAAATTTATTAAATCAGAATCAATAG +CATGTAGGAAACATTTGTTAAATTGGGACACGCTCTACTTTTCATGTTTTTGGATGTTAT +TATATCAAAAATATATACTAGCATTTAAAATATAGACCTGAGTTGGGCTCCCTTCATCTT +GTAGATTAATCACAAATGGACAGAGTTTAAACACATTAATTAAACACAGTCAGGGATAGC +TTTGGTTTTGATAATATACTAGAGACAGAATTGAGCAAATTTCCAAGAATTTTGAAGATG +TTTAAATGAAAAACTTCAATAATGAGAACCAGAACCACCACATAGGGATTTTCAACCAGC +TTTTTAAGTGTGGTATATTATCAAAACGACCACCTGATGGGAGTGGAAGCATGAGATAAT +GAGTGGGAAAAGTAAAGGTAAGAGCAGAGTATCTAGCAAAGGGAAAGGCAAGCAAAGAAA +TAACACCCCAGTAAAAAGGCCAAGATATCTTTAAATTGAAACATATGAGGATAAGCATAT +AAATAGTATATATCATGTAGGTTTCATTATTTAATGATAAAATTCAAACAGATAAGGCAG +GATTGATTCAATTTATTGGCTGCCAACATCCTTTAGGCAGCCCAGTTCTCAGAAACTGGA +GAAGTGTTGAAACTTTCTGGTCTGTTAGAGATTTGCCTTACCTATGTGTGCTGGGAGAAA +GGTCACTGCTGTTAAGGTAAAGACCATAGTGGGAACGCAGAATGGAGTGGTGGGCTTGAT +CATAGTGTGGTGTCAAAGGTTTCAGAGTCTTAGCTGTGGAAAAGCAGTAGAAACTGGTGG +CCATCTACTCTCAGCTTTTTCTAGCTTCATGTTCCTCATGGAAGAATCAAAAGCCTTTAT +CTGCGAAGCTTTTCCTAAAATTTTGACCAAGATCTTGGTGGTATATAACGAATATATCTT +TAAAGCAGTATGATGTTGAACTTGTGAGTTCTAAGCTGTAGAGGATAATTCATGTATTAT +TAGCAGAGTACATGACAGGGCAATACAGGAGCTGTTGTCTTAAACATAAGTTTGCTATTT +ATAGTAATACACAGCCATTATACTTATGAACATTTTAGCAAAAGACTATTAGTTTCCAGG +ATCTTATTCTTGGGGAAGTATGATATATGAAAATAGTTGATATTGTTATTATTAATGATA +GCTTGCCACAATGAAGTAGCAAATATTCAATTCATCTACATGAATAATGGTAAAAAATTA +ACAAACTAAGATGTGGATTTTAATCCTAGTGTAATCTACATTGCTCGGTAGATTCATCTA +GGTCAATTTCCTTGCAGTTTAAAAAATACTTAATCTGAGCCCAAATTCCTATTGCTCCAC +CTCCCCATATACCTTTATTTGCCACTTGTAAATAAGGCAATCTTCTGAAGCATTTTGGTT +GGGAAAAACCTATTGCTGATGCTTATTTTTGTTATTAGTATTCATTTTGTTTCCTCTAAT +AATTTAAAAGAAAGTGTAAAATAAACTTGAAAGCTAAAGGCATTTTTCTGCATTCTCCAC +TGATGTCAAGCATGCCATCTCCTAAAGGTGGTGTGTTGGAAATGTAGATTCCTTCATATC +TATCACATTTCTCCCATCTCCCAGACTAGTCATTTCCTCCAACTGCATTTCAGTGGTTCT +GAGGAGTTTGGAGGGCTCCTCCCTCCTTCTCTGGACTCAGCTCCACTGTCTTTTCCTGTT +CACTAGTCAACTGTAAGCTGAAGAGAAGCAGCTGGGCAAATGAGAAAGGTCCAGTAGAGG +TGAGCCCCTTCCATAAGGTCTTCTTCTGTCACCTCCAGACTTTGTCCAAATCCTCAGGGC +AGAACTGATGCTGGCATGTACTGCACTAGGCACCAGATGGCTGGAGTATTTTTAGTCTTA +GGGGAGGGACTAAAGAAGCAAGGTCTGATGGCTCGGGCGTGTCTCCAGCTTTTAAGTTAT +ATAATGAAGATCTGCTGATGATGGAGCCAGTGAAAGGAAATGTTGAGCTATAGTCTGGTT +CAGGGGCCTTTCAGCATAGAAGCTGATCTAATTATTTTACTCTTGAAAGTTTCAGTAAGA +TTAATGGTCTAGATTGTCTTTCTGTTATATAACAAATCATCTATAGAAGGATTAAATATT +AATTGATAATCTCTAAAAGAAAGTTCTAAAGTTTCCCTTTCAAGGCTCTCATAAATGTAC +ACTTTTCAAAATACAACTGAAGTTCTTGTTCCTTGCACCCGCCCCCACCATCCCATGAAA +TGATTGCAACATTTAACATGCCTTTACATGTCTATATCTGATCATGATAATGATATTTTT +CTACTTGTTACTTCTATCCCCACCCCACCATAATGTGGAAATTGACATAAGTTATTTTGG +AAAAGTAGAATGGAGACCAGATGTAAACATCTATAGTATAGTGGACAGAGAATTCAAAAT +TTTTTTACCTTGAAATCTTAAACTGTGAGACAGTTGATCTTTGCTTAAGATGACTGAGCT +TGTGAGATCCAATTCTCCGTTTCTTTGTGCATATGTTTGTTTTATACTGGCTAGTGTTTT +TTAATGGAAAAATAGTGTTTTGATTGACATTAGACTAATGTAGCATTTATGTTCTTTTTG +GAATGTGATACATCTGATACCTATTTTACTAGTAAGAAAAAAGTGTAATCTCATCATAAA +AAATTTATTCTTCTTTTGCCACATACTTATTTTGCTTCCATTTACTCCCTCTCATTGCGT +ATTTATTAAGATAATGAAGGAAAAAGAGGAAACATGGCTGTTGGCAATTTCAGCAGCTCC +GTAGTACTTACATTGTTCAATAAACTTAATAATCTACATGGACTAATTCTGACTTATGGA +TGTCCTGCTTCAGTAAATCACGGTGATTTTCTCCAGTGAATAACAGACGAGTGCAGTGTG +CCAGTACCTTAATTAAAGAGCGGCTCTCTTAGTCTTGATCTCATTTTAATTTACAGGGTA +ATACTACAATAATATCACTAATGGAAGGTACATTAAAGGGCATCAAGTAGCATTAACTGT +ATTAAATTATGGTACTTATGTTAATTAACTGCTGAAGCAAGATGGTTCTAATGGCCAAAA +AGGTCATCTAATGCATAAATAAAATCTACTCAGATGAGGGGCAAGAGGAGAAATTAGAAG +TAAATGTTTGTTCTGAACATCTTTTTATACAGACAGGGGGTTAAACTCAAAAGCTGTTAA +ATATAGATAATGTCCAAAATGTTTTCTTATTTACACCATTGGAAGCTTTGATTTTTAAGT +ATTTTGTTTCTTTGCAAGCTTTCCACAATTAAAATAATTGAAAAAGCGAGCACTGTATTT +GTCAGCTGCATAGATTTTATGAAATATAAACTAAAAATTATTTATTATTTCTTTGAGGTA +AACAATTTCAAAGAAATAATGTGATTTAATGTAATAATTTATAAATCTGAAAGACAAATG +AATCTTTAGTAATCTACTCATTTATTTTTAAGATATGCTATCAGCCATATATCAAGGTAC +TGATTTTAGCCATAAGACAATGGAAATTCTATTTTAACAGTAAGAACTTGAAGAAAGTGG +ACTGGAAAACTCCCATCAACATCTTCAGTATTTACCCTTTAACAAAATATTCCTGAAGGT +AATTATCGGTCATTTTTTCTCAATGGTCATTACACATTTCTTATCCCTTGCAGTGCCTAC +TCAGGCTCCATTATAGGTAGTTGACTGCCATAATAGTGAACAGTATTTTTTCCTTTTTCT +ACCTCCATTGTTTACCTCCAAGAAAGAAGCCTTGGAATATTAGCACAGAAGTTTCACTTC +GACAAAACTTTTTGGTGCCATCTTCACTTCATGGCTGCCCCTGCTCAGAATCACACTCTC +CCTGCCTAATCCCAGGACCTGCAAAGGGCCAGGACCAGAGCCACTATGACTAGGTGCCAG +GAGTGAGGCAGGCCCCCTACGTCACTCTCAGGAGTCCAGCTTCTATGTGTAAACCTTATT +CTTTGAATGTCACTGCCTTTATATTTGCTGTAATTAGAACAAGGTGGAGCTGACATCGTG +TTCTTGAAGCACAACTTCCACATGGTTAGTGCGAAAGATGTGATGTCAGGCAAGCAAGAA +CACTTGGGGAAATTCAAAAGTATAAAAGCAGTAGAGCACTTTTTAAATTTCTGGAAAAAT +CAGTTATTCTGAAGGTTCCCTAAGTCTTTTTCCTAGCCACAACTGAAATAAATCTGAAAT +ATTTACTTTTTACCTCTTTTGTAAGAGACATCCCACAAAAATGCTTTTAAAGCATTGAGC +CTGGCCTTTATCTATTCTTTTCCAATTAGTCTCAATTATTGAGGTTGGGCTTTACTGCCA +CTTAACAGATTCTGCTTTTTATAACACCTTCTTCCTTTCTGTCATCCATAAATACTTATC +CTCTACTCTGGGACAGATGCTGGCTTTGATGGTAGACAGACGAAGATGCACCAAGCATAG +TCTCTGCTCTTAAGGAGCTGATATCCAGAAGGGACACAGACTTTATAAACAACAACGACA +AAAAAAAAATGATGATAATGTGGGTTAAGTGATTTTACTGTGTGAATATTCAAAGTGCTG +TGGTAGCAGAGAAGCTACTAATGTAATCTGGAAAGATTAGTAAAACCTTTGATAAAGATG +TGACATGTATGATGTCTTGAAATATGGGTTTTATTGTGCCAAGCAGCCAGGAAAGAATGG +ATATCCTAGGCAGACAAATTATACCTAAAAACAGCACAGCATGTTAAGGAACTCCAAGCA +GTAAAGAATTGATGGAGTTAAGAGTCCTGAAGATGTTCTACCATCTTCCCTTTATGGGTC +TTCAGCATGTTCAGGAAGCTCTGAAGGATTCCTACCTCTTTCTCTCTGATTCTCCCATGC +CATAAGAAACCCAAAATCTTATGGAGTCTCCGTATTAATTGACTACAAGTGAGGAACAGT +TTTTAAGGCAATTGTAGTAAAGGCTATTCTGGTGTAACTGTGCAGACTGGAAAGCTATAA +CATTGCTTAATTGTGGAGCAACTATAGCTCCAAGCCCTGATGCTCAAGTGGAGAATCCAG +AAAAGCTCTCCATATTCCACAGGAGCCATCATATGGCAGTGGTCTCAGATTTGCTTACAA +AGTCAGTAGGACTTGTTGACCAGTCAGATTTTGGGGAAGACTTCCTAGTGAATTGGATGG +TGGGGCCAAAACTAAAATGGGGAATAAATACTGAAACAGGCTTTTAGTTAATTCATGATT +TAGCTAGTTATTTTGTTGTGCCATTTCAAGTAGTAGAAATTCAAGTAGAGATTCTAGTTA +GGGATTTGAAAATACTTGTCTAGTGTTGTAGAGAGAGATTTGAGCTCAAATATAGGTTTG +AGAATTATTACCTTATGTGTTATGGTGGACTCTTTGAGAATCGATGACATTGAGGATTTT +TTTGTTCATAGGTATAAATGACCATTATAGAACATTTACAGAATCCTGTGGAATACTACT +ATGTAAAAGGTAATTTCTGAAGGAAATTGAGAAATAATCTGAGAAAATTCAAAGAGAAGG +GAATGAGTTAATGTCATTCTAATAGTCCCCACTCATATTTAAGTAATAATCCTTTAAATT +TGTATAGCATTCAGTTTACAAAATTCTTGTCAGGTACCTTATTTCCTTTAGTACTTACAG +GACACTTGTGAGGCAGGTGTTGGTTAACCCCATTTTACAGAGGAGAAAACTGAGGACCAG +AGGAGTGCCGTGACTTTTTCTTTAACGTCACACATAACAAAGTGGTAAAATCAGGTTTTT +CACGGCAAACCTTAGGCTTTTTCCAAGCATTATGCTCTTACAGTCACACCAGCCAGAGAT +CAGCTCAGTATATATAGAAGACCCCAAAAATTCCCAGAGAAGCCATCTTTAAATAGCAAC +AATGAATCAATACATCTTATGACTCTGCCCCTCTTAGAATGTTCTGGGAGTCACACTCTC +CATGGCTTTTGGCTCAGTATTTTATTACACCAGGCTGCTCTGTGTTTATCTGAACTCTAA +CTTCTTACTTCATTTTTATCAACTTTCAAATGTGTGATTGGGCTCATTTGTCACATTGTG +TTAAGTCTAGGTGTTTTACTACTAAAATCAAATTGTGATGATAGCTTCTTATTTTTCCAT +GGGGAGACAAAAATAAATAAATAAGCTGTATTTTCTCAATGTTAATTTTTCTCCCATATT +TCTTCATAAACTTTTATTATGTACACCTGCTTTCAACTAATGGGCATCATCAAACACTAA +AACAAGTCATATATCTTAATGGATAAACTTGGAAATAGCCAACTACCTTCGCTTATTTTA +AGCAAGTTCATACTTCAAGTGAGGGCAATATGTTTTTCCTTTAACTTCCACATATAAGTC +CACATTCTCTCTTCTGAAACTATTTTGAATAAGTGTGCTGCCTCTTTCATATAATAAAAT +TTCATAAATTTTTAATCAATGATTCTCTCCACCAGGTCTTTTTTTCAAGCTAAATGGATA +TTAAACCATTCCACTAAAATTTAATTTACTCTCCTTTTAAAAGGCAGAATGAAGTCCAGT +AAATAAGAGTATTCAAATGAAAAGCATGGTAATCATAATTAAAAATTAAAAACCAACATA +AAACATTGCTACTTAACTCCAGTGGAAACATTTAGAATAAAGACTTTATCGTATGCACCC +ATTGTAAGTGGACAACTGAGGGACATTCTGATTTGGAGCATATTTTTAAAATCTATTAGA +AAATCTTGAATTATAAAGAGAATATATGCATAAGCAGCTCATTTTCCTCTGAGGTTTGTA +CTATTATAAGGAGAGAATGTATCTAATAATTCCTCCATTTAAATTATGAAATTCATTAGC +ATGCAGAAAAACAATCCGGTTTAGGAGCTTGTCTCTTTATCCTTAATTCCCTAGTGCCAT +AGATTTTTTAAGCTAGTGGGTCGTTAAAGGGAAGATGTCTCTTTTTTAAGAAACATAAGG +ATATTTAAGCAAAATACCACAAAATGGATAAATAAAATAATTTCTTCCCTCATTTAACTT +AGCATTTGTAAGGGAAGCTACATTCTAGCTACATCTGCATGCCCAAACAATGGGAGGCAG +CAGTACACCAGCTTCTGCAGCCCTGTTTTTTATCCTAAATCTGTGGTCTGCATCTTTGGA +ATGTCTTGCTGTCTTTCTGTACCTAGGATCAGAGTTTTTTCTTAACACGTTAGGAGATGT +TGGCCATTGTTTGATACTTAGTGCAAGAGTTTTTTGAGACCTATGTGATCAATGGTTCAG +TAAAGAGACTATTTCCATTCATTCTCCAAATAAATACAAGAACAAATGAATTTTATCACA +GTAATTTGATTGTGTGGATTGATATATTGATTCTGTTGCAATATGGGTCTATATTTTCAA +TTCAATAAGCCACTTTTAGAACTAAGTATATTAGTTTAACCAGAAATGACTGCACTGCAT +AAAAACTCATGGTTACTATTTCTACCTCCCTTTTATAGGTAGGAAAACTACATCTAAACA +AGGTTAATCAATAGCAAAGGGGAAAGGAAAATTTAAAAATTACTTATGTTGGTGTATAAA +TTTGTTTCTCAACTCCCCTTGAAAAACATTGAAAAAAATGGATGGAAAGGCTTTGAATAT +GTGAAACAGGAGCCTCACAAACCCTACTGGTCCAGAAGATTATAAAAGTAGGGTAGTTAC +TACACTGGCTCTCTCTTGCATTGTGACTGGTACCTAAGACAACTGATATTGTGCTATAAA +TATATTGAGAGGATAGAGGACAAGTCATTAGGATTTTAAAATCATTATCTACCTTATTTT +AGAAGGAAACATTGGCTAAGAGTCAAGAGAAATAGATTCTCACTCTGGTTGTGCTAATAA +TTCTTTGTCAGCTCAGAATAGGTCACAGTTACCATAATCAGAGTCTCCTCATCTACAAAA +TGAGATTTTTATACTATTTTACTGTTTCTCAGGATGTACTCTTCAAATAAAGTCCATGAT +GGTCAAAAACATTTTGGAAGTGTTCACAATACTTCCTTCTATGAGAATCACAATGTATAT +TCATATATTAAAGACCCTGAGGTGTCCTACAGTAAAGAAACATTTCTATTTTATTGAAGA +CAGAGCCTCTAGAACTTACTTAGTCAAAAAACATATATTAGTACCCATAAACGACTAGTA +TTCGCAGAACTCTTTAAGCTCCAACATTGTTGGACTCTTTGTAAGATTGAAGGAAATACA +TGAAAACATCGTGTGTGTGTGCATGTGTGTGTTTGTGTGTGTGTGTGTGTTTAAACTATT +TGCAGTGCTAAAAACAGATTGATTTTTCAAAGCAAGTTCCAACTTTAGTTATCATCCTTC +CTATATTACTGCTACTTTGGGTGAAAAAGTGAGACTGTCGTAGAGAAAGACTAACCTCAA +TGAAGAGTATCTCTTTTTTTTTTTTTTTTTAACTGTCGCTCTTATTTTTTGAACCTTGGA +GTACTATGCATCCTTCTTTAAGAATTATAGGAAATTAAGTACTGTATTGGAATAAATAGG +GATTTTTTTGTTTTGTTTTTAGGCTAGTGAAATTGTGATGGAAGAGTCAGCAAAGATGTG +AAAAATGAAATGCCAAGTGGTACAATCTGGTGTATTTTGTAGATAAATAGAGATGCTAAA +GGATTTTTATTCCTCCCATATGTAAGTGCCTCAAACTCTAATTACAGCAATGAGCTAAAA +TCATGTATTGAAAGAAAAATTAGATTAACCAGTATTTAATATATTCTTTTTTTTTCATTT +GCTTTGGAGGATATTCTTGAAACCACAAGCTAATTTTAGTTAAATGAATCTTGCCTTTCT +TTTGCTAATTAGGACTGTTAATGAATAACAAATCAGAGCCCAGTAAAACTGAACATTGTA +TATAGCTAAGGATATCACCTTGTCTAGGAATTGTGTTTTTGTCCTGGCCGCTTTTACTCA +TTTGGTGCTAACAGAATATCAGGGAAGCAAAGCTGTTATAACATATTGATGACATCCATG +TGTAATTATAGATACTCCAGTGCTGCTGGGAACAGGGAACAGATGGGGGAAGGGTGGGCC +AAGAGATGATGGGTGGGGGAAGTCTAAGAGGTCAGAGATTTGGCAGGTTGGAAGGAGACA +GCATCATTAACTCCAGTATTGGATTTGTATAGACAGGGTGTACGCCACATAGAGTCATAG +CATTGCAAAATCATTTCTTTTAGAACTGAAAAAAAAAACATAAAAATAATTTAATCTAAC +TCCTTTTTCAGATGTGAAACAGAATGGTTAAATGAATTAGTCAAGGATGACACTGTTGCA +TAACTAGAATTTAGACTCAGAGGGAACTTTCAGTTTACTCACTGATCTGCGTCCCGTGCC +TACAACTAGGCCTGGCGCATATTAAAAGTTCAATAAATATTTATTGATGGAATGAGAGAA +TGATTGCAGAATATCCTTCTAAGCATCACGTAGAGGACCATTCTGAGGACGGTTTTCCCA +TTAGGTATGCTATGGCCACCTCTAAATATTCCCCACACAAGACTGCAAGAGAATTGGAGC +TTAGCCCATTGTTTTTGGCTATGTCACTTCATCCAATCAACCAGATCGCAAAGCTTCAGG +CTTTAACCAATAGTCCAAACTTAAAGAATAAAATATATCTACTTCAGATAACAGAGTAAG +CTATGTACTTGGGTTAAATGAATACCACTCCACTCAAATACACACAATTTCTTTTATTAT +TTGTTTGATTGGTCCTTTTAAGATCAGAAATTGTGATCCTTAATCCCTTTCCTGGATGAA +GAGAAGTCCATGAAAAGGAATGAACTGCTCTCATTCTCAAGCAATATTTAGTAAAATCGC +AATATCACTATACATCCACGTCCCAAAGTTGTCTTCAAATGATGTTTGCTTCTTGAGTTT +ACCAACCAAAGGGACTTAAAATGCTATTTAAAAACCTTACAACTTGTAAATGATGCCTTT +ACATATTGATAGGTTCAAAGCTGGGGTTTCAAAGAGTTTGAGCTGAGGAGACATGGAAAC +AGGCAGTGGCCAAACTCAACTATATACATGTATCTGCTGAAACTTTTATGAACATATGTC +TTTATGAAAATAATTGAAGTTCATTATATACTCTTAAGTGGCAAAATAGGATTAAAAATA +TTAATAGCGTGAGGCTAATTATGAGAAGGAGGAAAAAAGAGAGAATGAGACAACACAAAT +ATAGTTGGCTAATAGTGGTGGAATTGTGAGTAATTTTTATCTAATTAGTTATGATTTTCT +ATTTTTTTTCATTTTACTCATTGTATCGTCAGAAAAAAATAGTTTTTAAAATTAAGTTAA +AATTCAGCAAAGTTGCAGGATACAAAAGCAACACACAAACATCAGCAGTGCTTCTATACA +CTAACAATGAAGGTCCAACAGGAAATTAAGAAAACAATTCCATTTACAATAGCGTAAAAA +TAATAAAATGGTTAAGAATAAACTTAACCAAGATCCAAAAGCCTTGTACACTAAAAACTG +CAAAACAGTGCTGAAACTAATTAAAGAAGACACAAATAAATGGGAAGACATCCTATGTTC +ATGGATTGGAAGTCAATGTTGCTAAGATGTTAATACTACCCAAAGCTATGTACAGATTTA +ATAGAATCTCTATCAAAATCCCATTGACGATATTTTCCGAAATAGAAAACTTCATGCTAA +AATTCATATAGAATTTTAAGGGACCTGGAAATAGCCAAAATAACATTGAAAAAGAAGAAT +AAAGTTAGTGGCGTCACTGGGGTTTTTATGTTGTTGTTCTTTTTTTTTTTTTAATTTCAA +AACTTACTACAAAGTCACAGTAGTCAAAACTGTGTGGTACTGACATAAAGATAGACATAC +GAACCAAAGAAATAGAATAGACAGTCCCAAAATAAACCCTCACATGTATGGTCAAATAAT +TTTCAACAACGTTGCCAAGACCATCGAGTGAGGAAAAGACAGTCTTTTCAACAAATGATG +TTGGGAAAACTGAACAGTCACATGCAAGAAAAACAAACCAAAAAAGGAAGTTGGACCCTT +ACCTTACACCATATACAAAAACTAATTCAAAATGCATTAAAGACCTAAATGTAAGAGCTA +AAACTATGAAATGTTTAGAAAAAAACAAAGGAAGAAAACTTCATGACATTAAATCTGGCA +ATAATTTCTTGGATATAACATCAAAAGCACAGTCAACAAAAGCAAAAATGGGTAAGTTGA +ACGTCATCAAAATTAACAACTTTTGTGCATCAAAGGACACTGTCAACAAAGTGAAAAAGC +AACCCACAGAATGGGTGGGAATATTTGTAAATCATATATTTGATAAGGGACTTTTATCCA +GAATGTATAAATTACTCTTACAATTCAACAACAAAATAATCCTAATTAAAAAATGAGCAA +AGGACTTAAATAAACATTTCTCCAAAGAAGATATATAAAAATGGTCAATAAACATAGGCA +AAGATGCTCAAGATCATTAGTCATTAGGGACATGCAAGTCAAAACCACAATGAAATACCA +CTTCACACCCGTCAGAATGATTACTATTCAAAAACATAAAATAACATGGTTGGAAAGGAC +ATGAAAAAATTGGAGGGTTTTTGCTATACTAATGAAATGGTACAGACACTGTGGAAAACA +GTGTGGCGATTACTCAAAAAACTAAACATAAAATTGCCATATGATCCAGGAATTCCATTC +TGGGTATATATCCAAAAGAAGTTAAAGCGGAAGCTTGAACAGATATTTGTACATCCTGTT +CATAGCAGCATGGTTTGCAACAGCCAAAGGTGGAAGCCACCCAAGTATCCATCGATGGAT +CAGCGGAAAACCAAAATGTGGCATATACATACAGTGGAATTTTATTTAGCCACAAAAAGG +AAAGAAATTTTGACACATGCTACAACATGGATGAAACTTAAAGACATTATGCTAAGTGAA +ATAAGCCAGTCACAAAAGGACAAATGTTACATGATATGCAACTTATATGAGTGTCCTAGA +GTAAGCAAATTCATAGAAATAAAGTATAATGGTGACTGCCAGGGGCTGGGGGCAGATGAA +AAAGAAGATTCATTTGTAATGAGCACAAAGTTTCAGTTAGGGAAGATAAAAAAGTTCCAG +AGATGAATGATGATGATGGTTGCACAACAATGTGAAAATATTTAATGCCACAAAACTGTA +CATTAATAATTAAAATAGTAAATTATGTGTTATGTGTATTTTAACAACAACAACAAAAAT +AACTGCACAAACAATACTCCTTGACTCAGCAAAGTAAAACACAGAAATTCTGACATATAT +CCATGTGTCTTTCTTCTCTGTCCTTATGAAATCTTCTAGTCTTTTCCCACTTTTAATGTT +ATTCTTGGTTTTGAGATGGAGGAAGATGTTCAACAGGTTTCGAAGTTTGTACGGGGCTTC +ACAATGAGGAGTCTAGTTGGAGGAAATAGGATGTGAAGCAACAGAAAATAAGTTTTAGAG +AAAGAATTTGGCCAGAACTTAACTAATCAAAGAACATTTTCTGTGTAGAGGAGCGGTGAA +GCACAGAGAGCAAGGGAGCTTAAGGGGCAGATATAATAATAGTAGTGGAGGATATTTAAT +ATCAGACTGAGTTTTTATTTCATACTGTAGGTAAGCAATTGGAACCACTATAGGCCCTTG +TAAAGTGGCCTATGTTGGGGATGATGCCACTGTTAGAAAAAGACTTAAAAGAGTGTGTTA +CCATCTGTGCATAAAATGGTTTGGAAGAGGGATGTAATTGACTGTTGAAATAACTTTCAT +GAAACATGAGGGTTGTGGATAGAGAAAGGAAGAAGTAAATGTGAAAAGTAGGTTTTAATA +ATACAGAAAGTAGGTTTGCCCCTAACATTTGCAAGGTTGGGGAAAAAATAAAAATACAAG +CCCACATACCATATGCCTAAATATGTATAAAACATAAGCTGAACTACACCACTGTTTGAC +TCATGTTTCCATCCTGAGTCCCATAGCTCACTCCCCATAGTGTGACAAAAGGGGCCATCA +TCTCTCCCCAGCTAGGTCTGCTGCTGCAAGCCTGAGCTAGAGGAAGGTAGAAGCTATGTC +CTTGACCCAAGACTCTTAAGTAGTAACTGGATCTACATGAACTTGGGATGGAAACTTACC +CAGGCAAGCACCTAGGAGGCCAAGCCAGGAAATTTATCCTCTTCCATGATTCACTTCTTC +ATTTCAGGATTTCCAGGTAGTTCTAAGCACCTCCCAAAATTACACCAAGAGTTCTTCTTC +TGGTAGTAGCCAAGCATGTCTTATCATGCTGACTCTCCGGTTCACAACAACTACAAACTC +TGAACTAAATATCAAAACAATTATTTGAAGGCCCTGGAGAATGACCACAGAGAATAGGGT +TCTGTACTTAGAGGCAGCAGCCAAGGTCAAAACTTTAAAAAAATAATAATAATAAAACAC +AAAGATAAAACAAAGTAAGAAGCTTTAAAAAAAAAAAGGAAATAGGATTTTGGATGGAAA +GTATATTACAAAAATATATTGTTTTTCTTTGGAAAAGTGTTTTTAAAAAAAGAAAAAAGT +AAGTGGCATTTTTGTGGGAAATTGTAAAGCTTCAATAGAGCTCTTTAACAGCATAGTACA +ATATTCTACACTCCCAGGAAGAGCAAGTCAGTTGAGAAATCCCATCCACATTCACTTTAG +AACCATTATTATTGCCCACCTGGCTGATTATGGATGGAGGAATATAAGGATGCAGCACAT +AACCCTTCCTGGTTCAAAGCTAGGCCTCCAGCTCCACTAGGGGCTCTCAAATTCTCTTTG +GTTCTCTCAGATCTTCCCACTTCTCCAGCCGTTGTTAATTTGGGAAGTCAACAGGTTACA +ATCTATCAGACAGGGCTTCTTCTGTGTTCCAGGGTGACCCATTTAAAGGAAGCAATGAAG +TGTTCTGGAAATGTATAGTGTTAATATCAAAGGAGACCCTGGCAACTGCCTTCTTAACCT +CTGCACTAAATAGAATTTAAAATATAAAGATCCTATAATGTATAACATACACTTAAATGA +AAAATAGCCCAAAGAAAGTGAGAAATATACTATAATTTAAAAAGGAAAGGGTTTCATTTG +GCAAATAGCTGTAACCATTTGATTAAATCTGTTAATACCATGCAGACATTTTGCTACTTT +AGTAGCAATTTATGTTTGTGGACTAAGAAAGAAAAGAATAATCAGTTCTGTTTAGTAAAC +TAGAAATGACTTTGTTAGCTTTGTGAGAACATGACAATTGGTAGGAATATAAAGGAGTAA +AACATTATTTAGCTGGGAATCAGATCACGTGAATTCTTATCCCAGAACTGTAACATGGAA +AATAATATCTACCTACTTCTCTTTCACGAATGTAGAATATAATACAAATAAATGTAAACT +CTTAAGTATTTTGTGCTTAGTATAATAGTTCCTGGCAGGGTTCCAGTTGCTAGAGATACA +AAGATGAAAAGCCACAGTCCCTGTCCTCAAGTTGCTACCATCTGGATGAGCTGACAGCTA +CTTCAAGAGAAAAATTATGAAGCATCATGGTTTGTGCAATGATAAGGATGTGCATAAGGG +TACTGTGGCAACAGCAGGGAGGAGGAAGAGCAGCAGCCCAGACCTCTGGGAGGACAGACG +CTTTCTGGATGACGTTCTGATAGTCTCAATTTCGTCAAGGTTATTTCTAAACAATTATCT +CCATATGTTATCTTAAACTAAATGAAATTCTCCTTATTAATCATTTTAAATGGTTGATTA +TCTAATGGTTGAAAATATCTTATGCCTTATTTTAGTACCAGATCTGTATATATGCTTAGA +AAGACATGCTTTATTTCTCCTTTCCCTAAGATAGGCATATCCAGAAAATTGATAGGCATA +ACCAGTGGAGGTGGTTTCAGACACACAGAAATACTGAGTAAAATGTGGACTTGCAAGACC +ACATGTTGTTTAATCAGACTGAATGAAAGGCTCAATTTTCAATGCTAAGTTAATCCTGTT +TTCATTAAATATAAATGTTATTTATGGAAAACAGGAGCCCTGCAGAAGCAAAAGAATATC +TCTCAGGGTTACACATTTTATATTTGTTTAGCACTGATGAGTTTAAACCAAGAGGCTTCT +TTGCAATTTGATTATTTGCTGCTTTCCTTGATATTGATTATTCTATCAGATTTTTCTACC +AACAAAAACATATGTAAAGATTCCAATGTTATTTTACTATCAAAATGAGATGCCAGAGGA +AATTACACACCACAGGTAAGTTTTTAATACAAACTAAAATCAGAAAAATCAAGTGTGGTT +TGTTAATGAACTCTGGTTTACATAGAGAGGCAACAGAGAGTGGCTTTAAGGCTGACAGAC +CTGGGTTCAAATCACAGCTCCTCCATTTGTTTACTTGATAGACTTTAGAAAAATCACATA +ATTTAAACATCTCAGAGTCTCAGTCCCCATCCATAAAATATACAAATGCTACCCACATTT +GCAAGTTATTTTCAAGTTTATTAATGTGTATAAAATGCAAGTACATATTAAACTAAGTAG +TGGTTATTACCATGAGGCTCACGAAATGGTAGCTACAATGAATATTGTGACTTTGAAAGT +AGCTTTGGGCCAGGTGCAGTGACTGTAATTCCAGTGCTTTGAGAGGCCAAAGTGAAAAGA +TTTCTTGAGGCCAGGAGTTTGAGACCACACTGGACAACATAGCAAGACCCCATCTCTTAT +AAAAAAGAAAGAAGTAAGTTTTGTTTTATTTTTAATTATTTTTTATATTAGTTTCACAAC +AATATATTGGCCCTGTCAAACTTAACCACTAGTATTTTGTCTTCCTCTACTAACTCTTTC +CACTTTCTTATATTGATGGACCGAGTTTATATTAATTCTACTATATAATTCATATCCTAT +TGTACTGCCATTAATGTGCACTTATCTGTCTTAATTGTTTCCTTCCTCTTTAAAGACCTC +AGCAGCTTAAATTTATCATTACCATATTCCTAGAGTTCTCTATTGGTAGAGATTCCCATG +AAAATTAAAACTGGGAATTACAAAGGGGGAAGAGCAAGCTTAGTTTTCTAAGATTGGCTT +CTTGAGCCCTGGGTAATGAAGTTATATTATACCCCATTTCCTCTGGGTTGCAGATGCTCA +TTTATCCTCACCGATGATGGATGGCCTACTTTGACATTTTGCATGGATGGCTCTTGAGAA +TGAAAATCATGCTTATAAAAGATTCATTGGCTCATCCTACAGTCCTAACATTGTCACCTT +GACACACAGTGACAGCATTGTAATATCCATTGACCCTGTTGGTCAGCACAAAAAAGGAGA +ATATGTTTCAGGATCATCTATGAGAGAAAAAGAGTTTGGGATTTCTTTTTCATAGAATGC +AATAACTAATGAATTTTTAGTTCTATTTCTCTTCTGGCTTCAGGAAAGCTGGTTTTGAAA +GACAGCAAAACCCTTGTGTCCTGGGAGGTTAAGAGGTCACCAACTTAAGAATCACATCCA +GTTTAGAGGTGTATCTATGAGTTGTGAGGAAATTGGAACAGGGGTTCCGCAGGAAAAGGA +AAAAAATATGTGAGTGCATTAGAGTGGACAATTTACTAAAGAAGATAGGATAAAAACAAA +TTATGTATTAATAAATGACATCAAAAACCCATTTAAAATTAGTCACTATAAGTCACTTTT +TGTTTAGTAGTCGTATTTTATATACATTTTATATTGAGTATATCCTATTTTAAAAGCAAA +GTAGACTTATGAAAATAAGCATTTTGGTGGGTTTAGGAATAACTTATAATCACTTTAACC +ACTTAAAAATAAAATGTGACTGACTTCAGTTTCCAGGGAAATTCTGACATAAAAATATGT +TAGCCCCCTGAATTAAAGAAAAAGTATGACTGAAGCATTAATAGAATGATAATTACAGAG +GCATTACCATAATCATAAGAGGAATGCCATGGTTCAGATTTAACTGCTTTGCACAAATAA +AACAGTAAACTATAAAAAATGTAAAATATAAAGGAGGGCTCTGTACATTGAAATATGTGT +CTTTGCACTCAACTAATTAGTTGCTACTGAATGTTTTTGCTTTGCTCAGTGGCATGTGGT +ACATAAATCATTGCAATATGTTAAATGCAAATGGTTGTTAATAGAGAAACCATCTGCTCC +ATGCTGGAGAGTTTGTTAAAAAGAATGTGGTGAACCTACTTTGGATAATGTTGAAAAACT +CAAATGCCAAATTTCTAAAATGAGCTGCCTCTGTTAACCCCAACATTACTAATACTCCCC +TGGCCTTTTAAATTCTCCAAGTTCATCACTAAAACACTCGTAACACAGTCTGTGCTGTTT +TAAACAACCCCATTGGCTACTTCTAAAGGCAGAATTATCCTATAGAGGTGTCATACCACA +GAGACCTACAGTGTTCTAAAATTGTGTTCAGGGATTTAGAACGACCAATAAATAATCAAA +CGATCCTCTCCAGAATATCTTTGCTAACATGGATAAGACACACTCCCTATCCCTGTGCCT +CCTAAAAGCTATTCCTTTGCAGCTATAGATCACTGGTAAGTTGCTGGCTGATGATGAAAT +ATCATGGGTATCATCAGTGTTTGCAACCTCCACCTCCTGTAATCTACAATACTGTATTTC +TTCAAAAGATCATCAGTGCAGAGGGGAGCCATGATTTCTCTCCCAACATACTTTATTAGA +TGTTGTCACATAGCTTCCTAATAATGTCTGCCAGACTCACTGGTGACAGTATAAAACATG +GGAAAATTAGTAATAGGAATCAGAGCCTTCATAATTTCCAATGTCACGCTCCACTTTTTG +GCAAAGAAGGGAATGTTCCTTAATCCTGCCCTTTCTAATCAGCTCCTGGTCAAGGTTGTT +GTCAATATATTTAAGAGCAAGCCGCCATGATGATCTACTATATTAACATCCATTGGAAGT +GTGTTCACATGATGCAATACCCAAAACAGAACCTTGGCCGTGAAAGAACAACCATAGAAA +TTAACTATGGATGAAGATCTTCAAGCCCACAATTTCTTTGAAGCCAAATGCAAGGTATGA +TTATTGGCCTACTGCTATCTTGGCTTTCTTGACCCTACTTTTTTTTTTTTCCTTTCATTT +CCCCCTTCTACTTTTGGCTTTTACAGTACCTGATTTCAGATTGTGCTTTTGGGGATTCGC +CTGCAGAAGAAAAGGCTGCAGGAGAGCTCATTAGCCCAGCAGACGCTCTATCCCTGAACG +AATTATACAATGAAAAGCTGCTTCTGAGGGCCACCAAAAAGAGCCAGGGCTTTGTGGAGA +TGGGCAGCCCTGCAGTGCAATAGAGGCTTTTTATTTGTTAAAAAGGAATTTTGTACTAAA +AACATTTCTCTTTGTTTGTTCTCGTGAAAAAAGGAGCCTCCTGAAGGCTGCGTGCATTTG +ATGACTCCATTTTAAAATGAACACTTGTCAGTTTCCAAAGGGGGCTGCTGCACTTGGAAG +TTACACAAAACCATTCTGAGATGGAGAGAGACTGGCACAATAATCAGACAAGCGATACCT +GAAAGGCAGAGTTCTGCCTGTGAATTTGAGAAGCTGGAATACTGAATTGGATTCCAACAA +TGATCCTGAGTCCTTACAAAGCCCATGTTTTAAACTTGGAGTCTAGAAAAAAAAAAATCT +TACATTATCTAATTACATTAGTTTATTGAGCTATGGTATCACTTTGGTTCCCAGAACGCC +ACTTTAATTTAATTTAGATTTTGTTACTTCTTCCCCTCCAAAAGGAAAACTTTACCATAG +AGGCATATTTATTGTTTTTAATGCTTATGTTTGGAAACATTTACTAATTTATTTTCCCAC +TTAATTACAGGGAACAGGAGGATTGATATTTACCAAAGTTTTTATGGAAAAAGAAATGAA +AAGTTTCTTTGATCTAAAATTATGATCTGACTTTTTTTGTTTGTTGTTTTGTTTTGTTTT +TATTTTAGGAGAGGACAGGGCTCCTAGGGAGACACGAAGAGCCAACAAAAGCCAGCTGCA +TTCATCAACCTTGAGTCTTTTGTGTAGGGAAGTGCATTTGGGTCATTGCTGCCTTCTCAG +CAGAATCCTATGGGGCCTCCCCAGTATACTTGCTGATATTTAGTGACACACACACCAGCA +GGGAGGGGATTCAAACACATTCCATCTGTTGGTGTTTTAATTTTTTTCAAGTCTACTTGA +TGAAGTGTTTGTCAGCAAACTTGTCATTCTGTTGTATTTGTGAGGTTTGGGCCCTCTTCT +TGGGCCCAAAGATATCTCTGAGATACAAAACAGAATTTCATAACCCTCCCTTAATACCTT +TTTTATACTGTCAGTGTCCTCAATTCTAAAACATTTTTCTCACTTTTATTCTGAAACTCT +TTTGGGTCATAAAGTTCAAGTTGTCTAGTTGGCTGACAACAGTGTTTATTTATCCTCAAA +GATAAGGTTAATTTTTTAAACCTTGCCTTCTCCTTTACAGTGTAGCAATCTGCTTTAAAA +CAGCAGGAAAAAAAGTTGATTTGTGAATAAAACATCTAGTTTTCTTTAAAACAGATGAAA +ACTATGTAGTTTATTTTTACTATCAGGAAAAGCATAGCATTCAAACACTGATATCCCTGG +AGTAGTTCCAAAATGTTGCTTGTAATATTTTTGTCTTTCTAAGAAGGATAAGACCCAATA +ATTCCAAGAGAGACTAGGGATCACGTCGTCTTGTAGGTCTGACCATGAAAATCTCTCCAA +ATGTTTTGAGTTTGTCTCATTTATTTACCTGGGAATTTAAATGCAGAGTTCCAGAGCTAT +ACGGAAAATCTGGGTAAAATCAGATAACTGATCTCTACCCTGCTTGATGACAGAATTAGT +TATCAAAATAGAGAAGAGCTAACATTCGAAACATTATAAGCCGGAACTACTTACTGTTAG +CTAATACTCAGAATAACTGACCCTTATTATTCTTTGTGTGAATCCAAAGAGCCCAAAGGG +TTATTTTCAAAGTTCTGTGGATTATGCTGGAAGGCAATGTGCTCAGCAGGTCACTAGACA +GGTGTGAGCCGCTGTGGCACAGAAGTTACAAACATAGCAGCAAGGGAGAGCGGATTACTT +TGGCTTTCTCCTTTGAAATGGCATTTTTCTGGGATAGGAACTTCAGATGGCATTTCATAT +TATTCATGACGGCAACCTTCAGTCCAGCACCATTGTTCTAAAAAACCCACCTGCAGGCTG +ATAACTGGCCCTCATCTCAAACAGTCTGAATGTCACCCACTGTATTTTACGTGCAGCCTT +TGCAGTACCTTAGAAATTCTTTTACCTCAACTAATCCCCATAAGAAAAGTGTACTGCCTG +CCCTAGATTTTCACTGTTTTCTCTTTTTCTTTAAAAACTTTCTGATTGGAAAGATTTTCA +TTCCTAGGTTATGTATGTGACATGGTGAGCAATACCCTCTTCTCATTTCCAGACTGAGGG +TATATATAGTCTTCTCAGAATTGAAAGTGTTCATTAGTTCACTTGGCATAGATTGTATAA +CTTGTGAATCTATTTTCTGAGAAGGGATTTCCTTCAGGCCCTAATGTATCAGAAAAGGTA +CAGTTACATCAACCAGCAACACACAAAAAAGGCACACCTGATAAGCCTCGATTTGAGTTG +GGGTCTGGTGTCTCCCTGCCTATGTGGCTGATGTGTTGCAGTCTGATTTGCCCAGGCATT +GCAATTTCTATAGATTTCAAAAAAGGAAAAATGTAGGAGACTAAGAAATACTGAACTACA +GCCAACAAGAAATGACTGAAGTTTTTCTCCATCAGTAATACAGCTCTGGAAGAAGATTGA +TCCCTGATCAATTTGGCACTATGAGGAAACTGCATTTCTTTGGCTCTGGGTATAGATTTA +CTACAGTCAGCTGGCCAGAGGCAAAGTGGTGTTTGAGTGAGCCATTCTGATACCCTTTAA +GACTGCAGGCTGGAGAAAAAGACCATTCATTTGATGGCAACCCAGATGCAGAGTGGGAAC +TTACCAGATAACTGGATTTCAGGTAGTGGCATGGACATGACCCATGCCCCTTTCTAGGAT +GGCAGCTTAACTACATAGGTTCTGATGGCTGTTCTGGATTTAAAATACTTTTCTCTCAAG +GTGCACACACAAATCTGCTATATATTTAGATTTTTTTGGCAAGTTTTAAAAAACTCCTCA +GAGATGTCAAAACAAGTGAAAAATTTATATCCAAGATAAAATGTTCAGTAGCTAGTTTAA +AAAGGAACTTTGATCAAACTGAGGGGACCAGAATAGCATTTGGAGGTTTATTGCAAGGCA +CCCCCTACTTAACACATTCTTTCAAGATTGCTTAAAGATGGCTAATCTTGCCCCTATAAC +AGCCAGGACTTTCTTATTTTGTATATGCATTTGTGAAGAATGTGAACATAGTAGGAATTC +AAAAAACAGCAGCTGCACCTTAGTTCTTTCACCTCTGCCATGATCTCTTTTCTATCCTAA +AAAAAAAAAAAAAAAAAAAAAAATGAAAAATCCTTTTTGTGGGGACATGTGCTGACCCAG +GAAAACAGTGGTGGCAGAAGCAGCTACAGCATGTTTTAGGGGTGGAAGGAAGAGGAAGAG +GTAGGGAATAAAGAACAAGGCAAAGCAAGCAGGAGGAGCAGACTTCTAGAGTGAGACAAA +AATGGTCACAGTAAGGCTTCCTATCACTTGATGGGCATCTTTGTCGTCACACAGACTGGA +TTCAAATCCATCTCTCCATCATTTACCATCTCTGTAACTTGGGTGATGACTTCTCTCTGA +GCAATAGTTTCCACGTCAGTAAAGTGAGAATAATGACTGGCCTCAGGCTGGGCATGGTGG +CTCACACCTGTAATCCTAGCACTTTGGAAGATCAAGGTGGGAGGACTGTTTGAGGCCAGA +AGTTCAAGATCAGATAGGCAATATAATGAGACCCCCGTATCTAGAAAACATTAGAAAAAT +TAGCTGGGCATGGTGGTGGGTGCCTGTAGCACCAGCTACTTGGGAGGCTGAGGCAGGACG +ATCTTTTGAGTCTAGGTGATTGAGGCCGCAGTGAGCCGAGATTGCTCCACTGCATTCCAA +TTTGGTCAACAGAGCGAGATCCTATCTCTTAAAAACAAACAACAAAACAAAACAAAACTG +GCCTCATGAGATTGTTGAGAGAATTAGCATATAGTGTGCTGCACTTGGTGTCTAGTACAT +ACATGGTAAGAATTGTTATTTGTCATGATTTATCTGTGTTAGTCCATTCTCACACTGCTA +TGAAGAAATACCCGAGACTGGGTAATTTATAAAGGAAAGAGATTTAATCGACTCACAGTT +CTGCATTGCTGGGGAGGCCTCAGGACACTTACAATCATGGCAGAAAGCAAAGGAGAAGCA +GGCACCTTCTTCACAGGGTGGCAGGACGGAGTGAGTGCCAGCAGGGGAAATGCCAGATAC +TTATAAAATCATCAGATCTCGTGAGAACTCCCTCACTATCATGAAAACAGAATGGGGAAA +ATTAGCCCCATGATCCAATTACTTCCACTTGGTCCCACCCTTGACACGTGGTGATCATGA +GGATTACAATTTGAGGTGAGATTTGGGTGGGGACACAGAGCCAAACCATATCATATCTGT +GGTTCTGACATCCTTGCCTTCTGACTGCCTATCTTCTCTGTCCCCATATTGGTACCCAGT +TTTTTTGTTTGCTTTTTTTGTTTGCTTTTATTATTATTATTATTATTATTATTATTTGAG +ATAGAGTCTCACTCTGTTGTCCAGGCTGGAGTGCAGTGGCATGGTCTTGGCTCACTGTGA +ACTCCACCTCCTGGGTTCAAGCAATTATTCTGCCTCAACCTCCTGAGTAGCTGGGACAAC +AGGTGTGCACCACGACACCTGGCTGATTTTTGTATTTTTAGAAGAGACGGCGTTTTGCCA +TGTTGGCCAGGATGGTCTCGAACTCCTGACTTCAAGTGATATGCTCACCTCGGCCTCCCT +AAATGCTAGGATTACAGGCTTGAGCCACTGTGCCTGTCCCTGGTACTCTTCTTAATCACT +ATGTTAATACCTCTATTTTACCAGCTTCCATATTAAGCCATTTTCCTTAAATTATTTCAT +TTTTATCAAGGGCTGTCCACTGTTGTGCCTCAGCCACTGTCAGATGCACCAGCCTCAGCT +CTCAGACCTCCCTCCCACCTCCAAACATTGTCTTGTTCTGAATTTCATTGTCCCCCTGAT +GACAATGGGTAATGAACATTTTAGTAAATTAATTCAAATAAACTGATTTCTGCTATGGTG +TCTAGGATAAAATAGAAAATTTCATATCCAAGTTGAACCCTGCCTCTCCAAGAGACTTAG +GATAATGCTGATAATGCTGTGTGCCTTGCACCTAGTAAGTGCACAATAAATCTTGGCTTC +TTTTATTACCATAATTATTGTTGATAGGAATATTATTATACTGTTCTCTGTGCTTTTACT +TATGCCTCTCTCAACTCTATTTTCCACTCTACAGTCAAAGTTCTCTTTTCCAAACTTAAA +TCTACTACTTTTGTGCTTAATATCCTCCCATGGCTTTTAAATGCATTTCAGATAACATCC +AAACTCTACCTCCTGATTCTAGTGCCCTCCATAGTGAGCCCTTGCCTCTCTCTGACTTCC +TCTGGGATTACTACTCCATTGGTCCCTCAGCTCTAGCCACAGAGCCTTCTTCTGTTCCTC +AGTTGCCAAGCTTGTTCCTGCTTCAGGACCTCTTCATGAGCTTCTAATTTCTCTACCTGG +AATGCTGTTTGCCTGACATTTCATGGATTCCTTCGCATTAATCAGATATCATACCAAAAG +CCACTTCTGAGAATCATTTTCTCTCCAACAGCAACCCCACCCTGATTATATTACCCTGTT +GTTGTTGTTCGTAGCACTGAGCTCTGTATAAAATAATAATCTATTTTTTAATTTATTTTA +AATTTTTTTTCTATGCATATATGTAATTTAAGTTATATGCATAAAATCCTTTTTAATGAA +ACATACAAAGAATGTATGTAGAATAGATCTAGGTTAGGGAGCTGAATAACAAAATTACCC +ACCTGTGAACCCACCACAGAATTTGAGAAATAGAATATTAGCAATATTGTTTAAATCCCT +TATGTATTTCTCCCAAGTGACAATACCATGCTGCTACATGTCCCTGACTTTTTGACCATC +CACACTCACATCTAGGATAACCATTATCTTGCATTATTTTTTCTCATTCTTTTGCTTTGC +TCTGTAGTTTTAGCACATGGATACTTATCCCTAAACAATATATTGTTTAGGTTAGTTTTA +AGTGTCGTAGTGTATGCCTTCTTCTGAGACTTGCTTTTCTAGCCTAATATTATGCTTCTG +AGAATCATAAATATTGATGAAATAGTATTCCATTGTGTGACTATACCACAGTTTATCTAT +ACTCCTGTCGATGGATATTTGGGTTGTTTTAAACTGCTGCTCTTATAGATATCCTTGTTA +AGAAATTTTTGGTACATGTGTGCAAAAAGTATCTAGGGAAATAAATACCTTGGAAGGGAT +AGGTAAGAAGCACATATTCAGCATTATAAAATAACCCCTACTTTTCTTCCAAAGTGTTGT +ACTAATTTATATTTTCAACAGCAGGTCTAAAAATTGTACTTTCTCTCTACGAGTTGGTAT +TTTCAAACTTATTAATTTTTTTCAGCCTCATGAATGTAATATAATAAGTTGTGGTTCTGA +TTAATAATCTCATTACTGATGAAGATAGAAGCTCTAAATGTCTATCATTCTTGTTTCTTA +TATTGGGAAATATCTTTCCCTGTATTTTGCCCATTTTTAATGAGAGAATTTATCTTTCAT +TTTAATTGATCCATAGAAATATATAATCAGGATTCTAATTCTTCATCAGTTTTATCTTCC +TTTCTCCAATTCATGGCTTGAATTTTCATTCTCTTTATGGTGACTTTTGATGAATAGATG +TTCATAATTTGTAATTAATCAAATTTATCCATAGTTGTCTTTATGATGATTATGTTTTTG +TGTTTTACTTAAGAAATTAAATCTTTATTCAACTACCATATGATCCAGCAATCCTACTTC +TGTGTATATATCAAAAGGAATTAAAATCAGTGTCTCAAAGAGATATCTGCACTCCCTTGT +TCACTGCAGCATTACTCACAATTGCAAAGATGTGGAATCACCCTAAATGTTCATTGACAG +ATGAATGGATAAGGAAAGTGTAATGCATATATACAATGTGATGTTATTCAGCCTTAAAAA +AAGAAGAAAATTCTGTCATTTGTGACAACATTGATGAGCCTGGAGAACATTATGCTAAGA +AATATAAGCCAGGCACAGAAAGACAATGCTGCAGGATCTCACTTATATGTGGAATCTAAA +GAAGTCTAACAAATTGAAGCAGAGAGTAGAATGATGGTTGCCAGGGGATGGGAGGTGGAG +AAAGTGGGAAAATTCTTGTCAAAAAGTGCAAAGTTTCAGTTATGCAGGTTGAATAAGTTT +TGGAGAGCTAATGTACAGCATGGTGACTATAGTTAGTAATATTGTAGACCTAAAATTTGC +TAAGAATATAGATCTTAAATGTTCTCCCCACACACACAGAGGTAACTATGTGAGGTTATG +GTTGTGTTAATCAGCTTGATTGTGAAACACTTCACAGTGTTTATACATGTCAAATTATCA +CTTAGTAGTATTTAAATATACACAATTTTTGTCTGTTAATTATACCTTAATAAATCTATA +AAAATGCAATCTTTGTCTTCCCCAAATCACAGAGCTACTCTTTCTTAGCTTCTTCAAAAT +GTTTTAGGATTTTGCCACTCACAATAAAGTCCATGACCCACCTGGAGATCAATTTTATAT +ATGGCTGTTTTAGTCAGTTTGCTCACTGCTATAAAGAAATACCTGAAACTGGATAATTTA +TAAAGAAAAGATGTTCAATTGACTCACAGTTCTGCAGGCTATACAGGAAGCATGGCAGCA +GCTGCTTCTGGGGAGGCCTCAGAGAGCTTTTACTCATGGTGGAAGGTAAAGCAGGAACAG +TCATCTTATCTGGCAGGAGCAAGACCAAGAAAGATGGGGGCAGTGCTACATACTTTTAAA +GAATCAGATCTCATAAGAACTCACCTGTACCAAGGGGATAATCTGCCCCCATGATCCAAT +CACTTCCCACCAGGCCCCACCTCCAGCATTGGTTATTACAATTCAACATGAGATTTGGGC +AGGGACACAGACCCAAAACAATATCATTCTGCCCCTGGCCCTTCCCAAATCTCATGTCCT +TCTCACATTGCAGTATATAATCATGCCTTCCCAGCAGTCCCCCAAAGTCTTAACTCATTC +CAGCATTAACTCAAAAGTCTGAAGTCCAAAGTCTCATCTGAGATAAGGCAAGTTCCTTCC +ACCTATCAGTCTGTAAAATCAAAAACAAGTTAGTTACCTCCAAGGTACAATTAGGATACA +AGCATTGGGTAAACATTCTCCTTCCAAAAGGGAGAAACCAGCCAAAAGAAAGGGGCTACA +GGCCCCGTGCAAGTCCAAAACCCAACATGGTAGTCATTAAACCTTAAAGCTTCAAAATAA +TCTCCTTTGACTCCATGTTTCACATCCAGGGCACAGTGGTGCAAGGGGTGGGCTCCCAAA +GCCATGGGCAGCTCCATCTTTGTGGCTTTGCAGGGTTCAGCCCCTGTGGCTGCTTTCATG +GGTTGGCGTTGAGTGCTTGTGGCTTTTCCTGTTGATGGGAGCAAGCTGTTGGTGTATCTA +CAGTTATGGGCTCTGGAGTACAGTGGCCCTCTTCTCACAGACCCACTAGGCAGTGCTCCA +ATGGGGACTCTGTGTGTGGGCTCCAGCCCCACATTTCCCCTCTGCACTACCTTAGTAGAG +GTTCTTCATGAGGGCTTTGCTTCTGCAGCAGGCTTCTGCCTGGACATTCAGGCTTTTCCA +TATATCCTCTGAAATCTAGGCTTTTCCTGGTGACAGGTGCAAGCTGTTGGTGTATCTACA +ATTATGGTCTCTGGAAGACAATGGCCCTCTTCTGACAGACCCACTAGACAATGCTCAAAT +GGGGACTCTGAGTGGAGGCTCCAGCCCCACATTTCCCCTCTGTGATAAGGCAAGTCCCTT +CCACCTATGAGTCTGTAAAATCAAAAACAAGTTAGTTACCTCCAAGGTACAATTGGGTAA +ACATTCTCCTTCCAAAAGGGAGAAATCAGCCAAAAGAAAGGGGCTACAGGCCCCCTGCAA +GTCCAAAACCCAACATAGTAGTCATTAAATCTTAAAGCTTCAAAATAAGCTTTAAGGTGT +GGATCAGCTTAAAGGCGGGCAGCTCACGAGGTCAGGAGTTCTTACACACTCTCTTTGTAA +TATGCCTGTTCCTGCTCTGCATTTTTAAATAAGTTCTGTGCACCTGCAGGCTTAACACCA +CATGGAAACCACCAAGGCTTATGGTTTGCACCCTCTGGAGCAGTGGTCCTAGCTGTAGGT +GGGCCCCTTTGAGCCACAACTGGAGCTGGAGCAGCCAGCATGTGAGGAACAGTGGGCCAA +GGCTGTGCAAGGTGGTGGGGCACTGGGCCTGGCCCAGGAAACCATTTTTTCCTCCTAGGT +TTTTGGGCCTCAGATGAGGGGGCCTGCCATGAAAGTCTCTGAAATGCCTTCAAGGCTGTT +CCCCCATTGTCTTGGATATTAACATTTGCATAAGTAAATTAACATTTTTCTTATGCAAAT +TTCTGTAGCCTGCTTGATCCTCTCCTAAAAATGGGCTTTTCTTTTCTACCACATGGCCAG +GCTGCAAAGTTTCCATACTTTTACACTCTGCTTCCCTTTCAAATATGTGTTCCAGTTTCA +AGCCATTTCTTTGCCCACACATATCAGCCAAAACTGTTAGAAACAGCCATGTCAAATTTT +GAATGCTTTGCTGCTTAGAAATTTATTTTGCCAGATACCCTAAATCTTCATTCTCAAGTT +CAAAGTTCCACAGATCCCTAGGGCAGGGCACAACGCAGTCAACATTTTTGCTAACACATA +ACAAAGGTGACCTTTACTCCTGTTCCCAATGACTTCCTAATTTCCATCCGAGACCTCCTC +AGCCTAGACTTCATTGTCCATATCACTATTCACATTTTTGTCACAACAGCTTAGCAAATC +TAGAAAGTTTGGAAGTTCCAAACTTTCCCTCATCTTCCTGTCTTCTTCTGAGCACTCCAC +ACTCCTCCAGCCTCTGCCAGTTACCCAATTCCAAAGCTGCTTCCACATTTTCAGATATTT +TTATGGCAATGCCCCACTCCTGAATACCAATTTTTGTGTTAGTTTATTCTTGCACTGCTA +CAAAGAAATACCTGAAACTGGGTACTTCATAAAGAAAAGAGATTTAACTGGCTTATGTTT +CCACAGGCTGTACAGGAAGCATGGTAGCATCTGCTTCTGGGGAGGCCTCAGGTTGCTTTT +ACTCATGGCAGAAGGCAAAACAGAGCAGATGTCTTACATGGAAAGAGCAGTACCAATGGG +TAGAGAGGTGCCATGCACTTTTAAACAACCAGATCTTATGAGAAGTCACTCACTATCATG +AAACCAACACCAAGGGGAAATCAACCCCAATGATCCAATCACCTCCCACAAGGCACCACC +TCCAACACTGGGGATTACAATTTGACATGAGATTTTGGTGGAGACACAGACCCAAACCAT +GTCAATGACCCTGAAGTGAGATCCAGTTTATTTTTTTCTACTTGGATAACTGATTGTTCC +AGCACCATTTATTGAATAGTTGTAGAGATATAGAATTAAATTGGCCAGGCATGGTGGCTC +ATGCCTGTAATCCCAGCACTTTGGGAGGCTGAAGCGGGCAGATCATGAGGTCAAGAGTTC +AAGACCAGCCTGGCCAATATGGTGACACCCTGTCTCTACTAAAAATACAAAAATTAGCCG +AGCGTGGTGGCAGGCACCTGTAGTCCTAGCTACTCAGGAGGCAGAGGCAGAAGAATCGCT +TGAACCCGGGAGGTGGAGCCTGCAGTGAGCCACGATTGTGCCACTGCACTCCAGCCTGGA +CGACAAACTGAGACTCCATCTCAAAAAAAAAAAAAAAAAAAAAAAAGAATTAAATCACCC +CAAGTATTATGATATTAATTAAACCATTAAACACCAGTCAGTATGGGTGGAAACCTGTAG +CGCTCAGCTGCATCCATGGGTAAAACCCTATGCTCAGCTACATGGGGATCATCAAAATGC +CACTTGCATTCATTTCTGCTGAAGCTCAATAAGTTGCATGACAGGGACCCTCTCCCATCC +CCTTTTGGTCCTCACCAATACAGTCTTTCAAAACTTAGTCTACCCCTAGCATCACTGAAA +ATTCCCACTTGTGGCCTGCACGCTTCCTCATCCGCTTCCACTGGACACTCTCAGAGAGCC +CTTTTGTGGGTGTGCTCTGTCTCTCATCCAGGGAATGCCTATTGCCTGAGTGAGTAATAA +ACACTTCAGTTTTTTATGATAGCAAACTTTAGTGTGATGGGTTTGACATTATATACCTTA +AAAGACAAGGGAGCAGTGTGCCCAGCTGTTAGTATCCTAAAAATAATTCACCCTTTCCTG +TTGATAAGCAATGCTACTTCTGTCTTATATTGAGTTTCTCTCTACATGAAACTCTTATCA +TTGAATTTTTCATTTTAGTGAACAGATATTTTATTTCTAGAATTGTGTTTGGTTAGTTTT +CTTTTTTTCTTTTAAACCTTCCTGATCATTTTTGATAGTCTCTGATTCCTCACTTGTGCT +TTTAATTTTCTCTTTATTTCTTAAGGCTATCAAACATGGTTATTTTGATCTGATTGTTCA +ACTTTTCAAAGTCTTTACAGGTCTAGTCTTTTTTTTTTTAACTTTTTTATTGTTTTTTTT +AATTGACATCATTCTTTTTACTTTTTCCACTGATTCTCACATAAGGCAGTAGTTTTCTGC +TAGCTTTGTGAGTTTTTTTAATTCTTAGCTTATAATTGATGGTAATTTATCTTTCCCAAT +TCTTTAAATAATAAAGCAAATTTATGTTTTCTTCTTTACGTTACTTAGGGGTAATGGGGA +CTGGATCTATTTAAAGTTATAATTCACAGATTGCAGTCTTAAGGAACATACCAATAGAGT +ATATTCAAACTTCAGAGCACATAGTGTAGTAATCAGAAACCGAGATATTTGTTCATTTTT +AACCACTACTTAGAGCCAAGCCCAAACAAATAAGTTTCCTTGCCAATTGTCTCAACAACA +TTTACAGGAAGTGTGGATGTCTCTATGAAATGTGCATATATAAACAGACACACACTAATT +TGCCCTTTCTCATGAGGCCTTAACCTTTCTTGGGTTTCCTTCTTTATTTAGGGTTATCTT +TGATGCAATGGCATCAGGTCTTTTCACAATACAAGTCCAACCACCGCCACCCTCAAACTC +TAGGCCACAGAGATTCGGTAATCCATGGCTTCAGTAATGCTCTGGTTTTATTGTTTATTT +CTGACCTCAGTGGATTTTTCTACATTGTTTTACACAGTCTCAAAAGTGTTCATAAATTAT +TGTGTCCTAAAAAGATTTTTGTGTATTCCAGACCACCGTCGTGGCAGAAACAAAAGTCTT +CATATTTTGGGCTGTTTTACCTTCATGAAAATGTATTCACTATGAAAGGGATTTAGTCTG +TTCTTCTCACCTTTGTCACCTCAGTGCCTGGAAAGTGTCTCCATCCTGGTTATACTTAGG +GTTGTATCCAGTGATTATGCACATCTGGCATAAGGCCTCACATAGACATATTTTAAAAGC +TCTTTAAGAAATTTTAATCCGATGCTAAGATTAAAATGATATTGACCTAGAACATACCTG +GTAGAAAGTATATTCTCAAAAATATTTATTGAATGAATGAATAAATTTATTTATTTGTTT +ATTTAGAGACAGAGTCTTGCTCTGTCACCCAGCCTGGAGTGCAGTGGCACAATCTCAGCT +GACTGCAACCTCCACCTCCCAGGTTCAAGTGATTGTTGTGCCTCAGCCTCCCGAGTAGCT +GCAATTACAGGCGCCCACCACCACACCTGGCTAATTTTTGTATTCTTAGTAGAGACAGGG +TTTTTCCACATTGGCCAGGCTGGTGTCGAACTCCTGGCCTCAAGTGATCTGCTTGCTTCG +GCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACCATGCCAGCCAGTCCTGTTGAATG +AATTAACCAATTTATAAGAATGATTTTTTTTTAAGGAAGAATTTGGCTATTTTCTGAAGG +GAGTCAAGTCATTAGAAGAAACGTATTGTATCCTTTGGGTATAGGAATTAAAGACCAATC +TGGTGGTGGCTCATGCCTGTAATCCCAACACTTTGGGAGGCCAAGGCTGGTAGATCACTT +GAGTTCAGGAGTTTGAGACCAACCTGGACAACATGGCAAAACACTGTCTCTAAAAAATAT +ATAAAAGTTAGCCGGGCATGTTGGCGCATACCTGTAATCCTAGCTACTCGGGAGGTTGAG +GCATGAGGATCTCCTGAACCCAGGAGGTGGAGGTTGCAGCAAGTGGGGATCATGCCACTG +CACTCCAGCCTGGGCAACAAGGTGAGACTCTGTCTCAAAAATAAAAGACCAATCTGATGA +TGGGGAGAATTTTAACAAGTCTGTCTCCATCTGGGCCTAATCAGCAGTGCCTAACCAGAC +AACACAAATCACCAAATATAATTTTTAAATGCATTCACTGCTAGGCCCCACCCCAGTCAG +AATTGGCCCTGACAATTGTGTCCATGGATTCTTTCCCTAGGTTACAGAGGACTAACTTAT +GCCCTATAGTATATGAGAGTACTATTTGAAAGAAATTATTTTCTGCTGACCTGATCCTCA +TTGAGCCATGATCTCAATTAAAAAAAATTCCTAAATTTATACTTAACTGGGCCAGAAAAG +ATGAGCAGGCATGCAGTGAGCATGAGAAAGGGAAGAAAAGCTAAACATGATTCATTCAGG +ATTATAACATATTTTCTAGATACTTTGATTGTAATACCTCCTTGTCAAAGTCTTGGACCC +CAAAATCTCCATAAACATATGAGAGCTCAGCTTTTAATTTTAACTACTTCATTTCTTCCA +CAGACATTTCATAGTTCCTTAAAAACTTTAGCTAATTTCATTCTTTACTTGGCTGATCTG +ATAGAAATAGTTGAGAAATGGCCAGAAATCCTGAATCACCAAGTTAACATTGGAAGAAAG +AGGACAGCTTGATTTTAAAAGCTAACAAAGAACAAAGGGAACTGGAAAAAAATTATTTTT +TGACATAAAATTGTAAATATTTTTTTTTCAGTGATATTTAACAATTCGTTTTTCACAATG +ACAGCTGTAAATTATTCATAACAGGCTATCTGGTCCTTAACTTTCCAGTTATCTGTGATT +ATAATGGTGAGTTGATCTGAAATGAAGGAAAATATTGATTAGAAACATTTGAAATATAGA +TGAAGTTCTTTAGTTAGAATATTAAAGTTGCACTTGGTTTCATATATCTAAGGAACATTT +GAAACTGTAACAGTGGAATTTATAGCATTATATACTACTCTTCTATGTAAGTCAAATCGT +TTCTTTTAAATTTCTGACCACTCAAATAATAGATCATTCCATTCGAATACATGGTTAAAA +TTTTGAAAGATATCAAATTAAAAATGAGCTTTTATTGTGACTCTAAACACTGTGAGAAAG +TGTTTACATGTCCTAAGAATGCATATATAACAATATGCACAACCTGAAAGTAAATACCTA +AGGTATGAATTTTTTTAATCTTTGTGGGGAAAAATGCAATTGAGAGAAAATATTACACTC +TGGACTAAGAAATATTAAGTGCTACCTCTACTTGAGTTATTTTAAAAATTTAGTTCTTCA +AGCCTTATTGAAGAAGATGATACTCTCAAGTTGAGCACTGGAAAATAGATGGGCATGAGG +AGATAGTACTTAATTTTTTTTTTTTTTTGACATCTATGACTAGAATTAATCAACAGCAAA +TGGCCACTTGCACATAGATTTGGTCACGAGTGGGGGTTTCCTGTTCTGGATGAGTCTGTC +TAATGTAAACTTTTTCTTTACAATCAATTCATTTGTTGCATTCTAGTGTTGATCTAGCCC +ACTGAAAATCTGGTCATCTTTTTCCAAACTAATACAGAGCACTGACCTATGGGGGAGAAA +AGCCTAAATTTTAGTGTATCTGTTTTGAAAGTAAGGAATTCTAAAGAGGACCTTACGATG +ATAATCAAATCATTCCAGGAAAAAAAAAAAGGCAGAGAGTTTAACAACATCTACAAGCTG +CTGTTGCTTAAAAACACAGTATTTGAACTGCAATTTGAGCATATTTTTACCCTTCAGACA +TTACAAACATGCCATAACACCCTGCTGTGAGGACAGCTTTGGTGCCCCAGAAGTAAAAGA +GTTTAGCTGTGATTAAAGGATTGAAGTCTGTGCCTTGAACTGACAGATTAGTTTATGCTA +GGTTTTCTCTGTTAATTCTAGACTTGACAGCTCCACTGTAAATTAATCTAAATTATGGCC +AACTGCTACAAGGCTGATCATTGTCTCACAAAAAAATATAAAGTTCTATTGAAAATGCGG +ACGTCTCTATCACCAAATGTTACTCCAATTTGCTAGAAATCTGAACAAGGCAACTTAAAA +CACACACACAGGAAATTGCAGCTCCTAGATGCCAGTAGAGCTATAGAGATTTGGACACAC +AAACTGAGCTGTTGGGGAGAACGGGTCTGACTTCTGTGGTCACTGATGTGTGAGCCTCAG +TGTTTGTCTTTAGCAGCTCATGACAATGTAATTACATCCTGCGTGCCCAATTTTTCTCAT +AAATGAAGTTGATAAATATAAACTACAGTTTATGATTGTGAATCACAGCCTGAAGCAATA +CAGCATGGTCATTGATTGCAGAGAAATATAAATAGGAGATGATAATAGATTGACTGAATC +TGAACCCTATCACAGACCAGTTAAGATATCAGAGAATCAGAGAATGGCTTAAGAGAAGCC +TTAGTTTCCCAGGAAGAGAAGAGAAAACAGGTCTGGTGGGCAAACAAAGGCTTTATAGCT +TCATTAACCTATTCATACCTATAGGATGATCATTTCTCTGGAAATTGCCCCTATCTGAGA +CTTGATTGAGAGTAGGCATCAGAAGTGAAGGGTGACTTTTTCTATTTTCTGTCTGTCCTT +GGCAAGCTCCCCCACCCCCAACACATTTGCATCACTGATTCTATGTTCTTAAATTTGGAG +CTTCCTGTTTCTGTGATTAGAAAACCTACAGATAGGTTTACATTTGCATTCACTGTTCAT +ATCATTAGGGAGCTGAACAGACAGTATTGAGTGCATACACCGTGCTAATTCACCTTTACA +TCTGAAGGAAAAAATACTAAGTGTGATAAGATGAAAAAAAAGGAAAAGAGAGAAGTGGAA +ATACATATTTATAGAAAACAGTATTTTCTCCAAAACTATCACGAGATAGTCACTGCTATT +TATTGTGTAACTTATGTAAACCCAAAACAGTTGGGCCCAATCTGGTCCCCAGATATATCT +TATTTGGTCGACACAACATTTTACTTATTTTTTATTTGCATACCTCTTAATCAAGCCTAA +ACTGTTCACACATGGTTGCTGCTCCCGCCACACCCTGTTGTCTTATACAGGGTCTGCTTA +CCTGCCTGACAACCGACCAACCCTTTGGTCTATAGCACTCAAACATATTGATTAGAAAAA +TTGATTTTTTTTAGGAAAATGTTTAGTGGGCATTATATACCAGGTACTGAACTTGACACA +CCAAAACAATAAATATAATTTCAGGCAGTGATATATACCATGAAGAAAAATGAATCAGGG +TAAGGGAAAGAGAATAAGAAGACAGCCACTTTAGGAAGAGGTGATCTGAGAGGTCAGAAT +ATCAGAACAAAAGTTAAAGGATGTGAAAGAGTGGGCCACGGAAATATCTGTGGAAGAACA +TTCCAAAAAGAGAAACAGTGAGTGTAAAGACCCTGAAGAGAAATAGAAAGTACAGTATGG +AATACTCAAGGTGGAAAGTGATAGAAATTAAGGTAGGAGAGATGAGCAAATGCCAAATTG +TTTAGGTCCTATAGGCAACAGGAAGCCACTGGAAGATTTTCAGCAAGGAAATCAAGTAAT +ATAATTTATATGATAATGAATGGATAGTCTCTAATTCATGGGTAGTACATAAATAATTTA +TTTGAATTCTGAAAAGTATTTGCAAAGTCAAGTAATGCCTGTGAAATTTTATCTGCATTA +TCAGTCTGCTTAGCAAATCAATATATTAGAAAGCATTTAAGTAGCAACTAATATGTGCAC +ATCCTATGCTAAGCCCTGTTTAGGATGTAAAGATCACTTAATATATGGTCCTTGACTCAT +AGCCGAGAGGCTACTTTCTAACATCTAGTCACCAGTCACTGAGTATCTCTCGTCCATGCC +TCCAGAATACATGTTACATATTTCTTCCCATGATTACTAGAAAGACTTAAGAAACTTAGT +TTTGTTATTGATTTGTATACATGACACATAAATCTGCTTCTCGTGTAACTGCTATCTCAC +TTCTTTAACTCTATAAATTTCATTGTTTTAAAGAAGAATCAGTTCTTATATTGCAATATG +GAAGTACATAGCTCCAAAAAAAAGGCAAAAGATCTTTGAAATGGGTTTGAAAAAATATAT +ATAATATATATAGTATTATATATTTCTTATATTATATATTATATATTTCTTATATAAAAT +ATAATATATATTATATTATATATAATTATGTATAAAATAAATATATATAAATTATATATA +AAATAAACATATAAATTATTATATAAAATATATGTTATGTAAGAACTATATAATATATAA +TTTTTATATAAAAATATATAACATAATATATAACATATATAATCATTATATAATGAATAT +ATACATTATATAACATATATATATATACATATATATATATATATATTTTTTTTTTTTTTT +GAGACACAGTTTCGCTCTTGTTGCCCAGGCTGGAGTGCAATGGCGTGATCTCAGCTCACT +GCAACCTCTGCCTCCTGGGTCAAGCAATTCTCCTGCCTCAGCCTCCAGAGTAGCTGGGAT +TGCAGGCATGCACCACTATGCCCAGCTAATTTTGTATTTTTAGTAGACATGAGGTTTCAG +CACGTTGGTCAGGCTGGTCTCAAACTCCTGATCTCAAGTGATCCACCCGCCTCGGCCTCC +CAAAGTGCTGGGATTACAGGTGTGAGCCACTGCACCCAGCCAGAAAAAAGCAAATATTTT +AATCACTGCCAGTACCTCCTCATCCTGTTGAAAGCTGATGTCATTTTTGACACTCGGGAA +ATGACTTCTTTATGGAAGAAATGATAAACTAGTCTGCATCCTGCTGCAATAATCTGAAGA +AAGAGTGTTTGCTATTTCAATTCTGAGGATCACTTCATAATTGTAACATCAAATTAGCAT +CTTGGCTTATGCTACACTATTTTGTAGAATCTTAGAGCGTGGCTGACAGGGTCCATGGAG +TACTCAGCTGGAACAGACTGATTTAAATATGGCAGAGACAACAACAGGGGAAGGGAGAGC +CCTGAACAACATTGCAGAAAGCGTGAAGCTCATCCCATATCCAGCACTCCCTCGTCTCAT +GCTCTTGTACCACCATCACAATCTCCTTGGGCATCCAAAGAGCACCCATCCCTGAAACCA +TCCATCAGAATTACCCCAACCTCTACCCATTTTCCTCAGAACTCTCTCTCTGATCAATTT +TCTTAAGTCTGTGTGCCATGATATTTTCACCTCAATAAAATAATTGCTATTTAAAAGAGA +CGGTTACACCTTGCCCAAAGGAATAACTAAAATGGTGGAAATTCTGGATGCACTAGCTGG +CAGCTTAGGAGAGTTATGGAGAAGAGGCTTTTTATTTCCTTTGTAATACTACCACTTGAT +GTCTAATGTGAGGTATGCTAGATACCTGTGGTTGTTGGTTACATGTTATCCTACTGCTTT +AATTACTGGAAAGCTAAGTGTTCACTAGTTAATTTTCACTGTGGCCTCCACTATGGGGTT +GCCGGATCTAAGTAGGAACATGAATTAGTCTGTGCATTATTCCAGCACAAATGAAGCCAA +AGCTGAACAGGTGCATGATGTAGTGCAGTGAAAACACCATGAGCTTTGGAGTCTGAAGAC +CTAGATGTGTGCTCAGTGTCCACTGCTTGATGAAGCAGAGGTGTGGGCAGGTCCCTAAAC +CTCTGAGACTCTTGCATCAGCTGTAAAATCCAGAGTTGCTGTGAAACTGAAACACGGCAT +ATATGTTAAAACACTTTGTAAACTGTAAAGCACAAGGCAAATGATGCTATTTTCAATTTA +AGCAAAAATAGAATAAGGGCAGATGAAGATTTCAAGACCTTTCAGATTTTTTTAAAAGTT +TCCCTACCCTTCTTAACAATCTGTTTTTATTTTGGCTGATTACTTGAGGATGAGCTCAGG +AGAATATTCTGAGCAAATGTTTGAGTTTGGTCTTAGTGCCTCGCCCTTTCCCTCCCTTCT +GTTTCATGGCTTTTCCATGGCTGGCTTTTATCATACAGAAGGCTGGCTGACTGAATTTCT +TAGGAACATTTTTATATCTTGTCTAATGGATGGTCAGGGTTTCATATTGCTGCTTCTTTT +TAAAAGTTAATCAAAGAATTACAGGCAGGTTTTTTCCTTGTGTTGTAAATATGAATTAGT +CTAATTATAGTTTTCAAAAGAAAGCATTTTCACACCTGAATTTCATGAACATATGATGGA +GAAATGACAGGGCTTATTCATTGGATGGTTTTCTGAAGGAAAAAAGCCCCACTGCAAATA +CAAATAAAACAGTGTCTTGCTGTATTCCTAGGGAGGGAGTATAGAATTGTGTAGTCTCTG +TGCCAGAAAGCCACATGGAGTATATCATTGCAAAGTCTCATAGTCATGAGGAAACTGGGG +GGTCATCCAGTCCAATTCAGTCATCATTTAGAATACACAGGAAACATGATTTAATCTGCA +ATATAACTGCGTTCAACATCATGCCTAATTTCATCTCCTTATCTGAACCATAGTTTGCAC +TTAATAAATGTTAGTTAAGTAAAATTAATAATTATCCCACTATTATTTCCCCCAATAAAA +AAACCTGCTAATAATATCAGTCTCTTTTCTGGTTAATTCTATTCACTTCATGCTTTTATT +TGCTTTTTCCCTTTGTGGAATGTGGATCCTCTCTTGCCAGTTATATAAAGATTGCTTCTC +CTTCAGACGTTAGCTCAAGGCTCATCTCCACCAACAGGCACCATTTCATATTGATCACTT +GCTTTCATCTTATCTGAACTCAATTCAATTTAACATTTAATCGTTTCAACATGCACATGT +ATATTTCCTCAAATATTATATACAATACTTTCATTATTAAATAAGATGTAGTATGACATA +ATTGCTACCTATCTTACATTGTTCACTATTGTTTTGATCAGTTATTTTGTGTTGTTGGTC +TAGGTAACATTTGGGGGAAAAAGAACTGTCTCTTTTTATTTTCTGATGCTGCACAGTGCC +CAGTGGAGAGAGGAGCATAGGATAGATGTGAAATATTTTGCTTGACTGACTAAGAAGAAT +GTATAAGTATTTCTTGGGTAAACTGCTTACACTTATTTTATTGAAAATATGTCATAATGA +TATTAATAATTTAAGTCACTTTACCCTAATACAATTATTTCTATTTTTGCAAATTATCTT +CCAAACCTTTTTCACACCATACGTATTTTATATAATTGTTTTCAGAATATACTTACTATT +TTGTATTCGGAATTTTAATTTGTATTTACCATAATCATTTCAGTAATTTTACATAATTCT +CGTGGCTATCATTGTTAACTGCATAATGAGGTACAGCACAATATTCCCTTGTTTATTAAG +CTATTCACTTATTATTAAACTTTTAGCTTTTCCCCATTTATTTCTTTCATAGGTTACACT +GCAGTGAAGACCTTCATAATAAAGGTTTTTTGTTGTTGTTTTACTTGAATTATTTCATTC +AGACATATTCTAGGAGTGAACTGACTTGGTTAAAAGACTCATTGAATTTTCTCACTACAT +TTTACATATAGTTTCACAAAGTGCTTCTGCAACCATTTACGACGTGCTCAGAAGGGCCTG +GGGTACTCTCACATGAGCTCTTAGTGACCTGATCAAAACTGCACCCCTTGGTTTCACACA +TAAGAAAGCATCTCCATCATTTTTTTCCTCCTAACATGTATTGAGCAATTGTTCTGTGCC +AGGCAACATACTAAGTGCTTTGAATGCTTATCTACTCTGAATCAATTATTCTACCTTTAC +AGATAAGAGTAGTTCCAAGTGCGAAATTACCTGCTTAAAGTCAATTGTGTAGTAAAATAC +AGAACCAAGAGTCCCAATCCGTGTCTATCTCATATGCACATAATTGTTGATCTACCTTTT +GTCTCCCAGTCCTCATTCATTATGTAAAAAAGTACTTCCCAAAGTATAGCACTTGTAACA +CTGATGGGAAACAAAATAATTTATATGATGCACAGTCATGTATTCATTTTAATGAGTATA +TTGAAACAATAACATTTTGGATACATTAAATTAAATACCTTGTTAAAATTAATTTCACCT +GTTACTTTTTTTGATGTGGCTAGTTAGAAAATTTAAACTTACATATGGGGCCTTGTATCC +AAAGCTCACATTACAGCTATATTACAAAGTGTTGACTTAAAAGACAGTTGAGATCCAATA +TATGGTTTTGGACTATGGAGCAGATTTCTTTCCTAGAAGACTTCATTCAAAATGGTCAAA +ATCAACTCTGAGATATTGTCTTTTTTCACACCATAACTCCATAACTCCAGCCTGTATTAG +GAACTGTCCAAAAAAGTATTGATGTTCCCTACCAAAAAAAGATAACCAAAGGGTCACCAA +TGTGGTGAATGATTTACTGATGGTACGCATTAATCTTTCTTGGCACTCCAGGGCCCATAA +GAAACAACTGGATTCCAGCCCCATTTTTAAGAAGTTAAAGGATAATAAAAAAAATTGTAC +ACATGAATATATATATTCATTTGCATATAGGTAAGCCAATATAATTTTTATATATGCAAT +TTTACAGTCGCTTACCATATGTGATGTAATGATGTCTATAAATATAAAAATTCAAATTCA +GCCATAATACAGAATAGACAGTATCTTCAATGAAACATAATCATATTTTTGCATATTTTT +TCTATATGCCACTTGGCATGAGATATGATTTGTAACAACTACTTAACATAATCCCTCAGG +ATCTGAATTCATAAGAATTTAAAATCTGCTTTAAAGGTCTGAAACTACATTGAGTTTGTT +TTGCTTGGGGGAGGGCAGATTTTAAGCATACCACTGTTATGCTCAAGCATTATTTTATTT +TATGTTCATTCAAAGCTATATTAAACAGTATGGAATTAACCTCTTTTGTTTCTCCAGCAG +CAGTAAACAATTCCACAGAAACTCAATTTTCTTTCAGTTCATAAATGTACTATATTCCCC +ACTGTGTCAAATTACCTTCTCTTCCTTTCCAGTAAGCTGATGACAGATAAAGATTCTGCT +ACCCATGTCTGTTTCATGCAACAATAGCAGTTGACGCAGATCTGTAACAGCTCACCTGGG +CAGTTCTGTTAGTGTGTGTGTGTGGTGGGGGAACATAGCAGAGAGTTAAGTAATATTTTT +AATGGTATTGTAACCATGTCCACTCAGAAGGTAATTTAATCTCCACAATGTTAGACCTCC +CACACAACAAATTGTTCCCTTTCAGTGTGGCACAGTAGAGAGAAAAGAGCACGACACCAG +CTGGCAGTTGCTGCTATGGAATACTACCTACAAATATAGATCGGAAGTTGTGGGTCATCA +CTCATATCTCAGAAGGACTTTTTTAGGATGGCTACTGAACAGATGTAAGGGCACTTTTAA +TTAAATATAGACCCAAAAAATCTGTCTCAAAATAAAGTTTGTTGTGACACATTCTCTCCA +GAGACCTGGAAATTCGTAGCTAAAATTAACTTTAGAACAAAAGGGTTTAGAGTCAAGGAT +GATGTTCCAAAGGGCTACAGAATGCCAGCATGTTGGGTTATAGCTCTGTAGACAAAAACT +ATTTCTGTAAAGCTCTCTGTATATGTGTTTATATTTAAAGGTACTCGAAAGGAGAAAGTC +AGACTTCAAATTCTTCCCAAGTTATTAGCATATAAGCTACTAGGACAAAATGAAATCTTC +CACATTTTATTTCTAGACTGAAATGATGCAGAATTAACTCATCTATTAGGGATGTAGGAT +GTTCTCTGCTTTTTATGTTTTCTTCTGAAAAATGTATAAGAAATTATATGAAATACTTCT +AAAATATCCATTTCAAGATGTTTCAGTTCATTTCGTTCACAAAAGCTGCAGACCTTTAAA +TTTCTGGTCATTTAAAATCCTATTTTAGTATTCCAAGAAGCCTGGGTTTCTCAGTCAGAG +TTACTGTACAAAATCTTGATTAAATATTTATAAATTTCTTAAAATGTATATTACTTGCTT +GATCTATTGAATAAGCATATATTCATTAGTCATTTTGTACAAAGTGCTGCTACAAAGGAA +CAATGTCTTTTATCTGTTCGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTTCTCTAGCAC +ACTATGGGTGCATAATAAATGTTTAATGACATCAAGCCATGTGATAAATCAGTACTGTCC +TACAGATATAACAGGCAAAGGGGCTGAATCCTGGACTTAGGCTTGGCCATTTTAAACCCA +TGCCTGCCCCAAAGAAGAAGTACAGATCTTAATGTTTGCCTGAAATTGATTTTTTTTTAA +ATACAAGACCCTGAGAAATATAGATAGGAATTAGAAACATGCAGATTTGAAACTCCTCGA +TGAAGGGCACTGAATCTTCTGAATGTCTGACACCAGCATGCTTGGTTCATGTCAAATAAG +TAGTAAATAATTCTGGAGTGAATTATTATCATTATGGCCTAAAAAACTTCATTTGTAACT +AAGATCAGATTTACCCTCAGGAGAAAGTTTTCCTGTGTGACTCTTAAATCCTGGAATACC +TTTATGCCTGTGGATCCCTGTTGCATCTTGGCAAGCCTGGAATGTCACAACAATTTTTCT +CATTTGTAAACAGGCAATTTTACCACAAAATAAATAAATAAATAAATACATGGCAAATAC +GTGAGCCATCCAAATTTCCCCTAGTCCTTAGTCTACTGTAGTTACTCTGTGCTAAAATCT +TTATTTTTTATTTTTTCTGTCTGTTTGTTTGGTTTTGTTTCTGTTTTTTTGTTTTTTGGG +GGTATTTTTTTGTTGACATGGAGTCTCACTCTGTTGCCAGGCTGGAGTGCAGTGGTGCGA +TCTCAGCTCACTGCAGCCTCCGCCTCCCTGGTTCAAGCGATTCTCCCACCTCAGCCTCCT +GAGTAGCTGTGACTACATGCACACACCACTATGCCCAGCTAATTTTTGTAATTTTTAGTA +GAGACGGGGTTTCACCATGCTGGCCAGGGGATCAGGATGGTCTGACCTCAACCCGCCTGC +CTCGGCCTCCCAAAGTGCTGGGATTACAGTCATGAGCCACCGTGCCCGGCCTAAAAACTT +TAAACAAGGATGGCTGAAACATCGATCCAACACATAATAGGAACCCCTTTCTTCTATCTT +CATGTCCCCATTATCTCCAGGATTCTTAGAGGATTTTCTTACATCCTTATTACCTCTGGT +TCCAATGTCTTAGGTCTCCTGTCTTCCTTCTGTTTCTCCCCTCTTCCTTCTTTTCCTTCT +CCCCCAACATGAATCTAAATGTGTGCAATAAAGATGATTCTCAGGTGTGCAAAAATACCA +CATTTGTTTATTTTCTTTACCTAAAAAAAAAAAACATTGGTGGCAGAATTATTTAGTACA +AGTTTCTCATTTCACCTTGCATAATGATCTTGTGTGGTAAGCACTGTTGCTTTCCTCATT +TTACAGATAGGGAAACTGAGAAGGAGAGAAGTTGACTAACTTATGTAAAGTTTCACAGCC +AGTACCTAAAGTGCTAGAAGTTGAACTTGACTTCTAAGTTGACTGTGATTCACTGCCTCC +TTCATTAGAGCCACCATGAAGTAACATACTAACAGTGAGCACTCACTGAGTACTGCCTAT +GTAACAGCATTCTTCTGAGTCCTTTAAGTGCATTATTTCACTTACTCTTCATATCAGGAA +CATGAGACTTGCACTGTTGTTATCCCAATGTGACAGATAAAGAAACTGAGTCTCAAGGGG +ACTCAGTTGTTTATAATCAGACACCTAGTAAATAATGGAGTCAGGATTCCATTCCAGGCA +GTCCAACACTAAGACCTTGTCTTTATTTTGTAAACAGTTTTATTGAAATGTAATTGACAT +ACAATAAACTGCACATATTTGAAATGTACAATTTGATATGTTTTGACTTATGTATACATC +CGTGAAGCCATCACCACAAGCTAAGTAGTGAACATATCCATTATGCCCAGAAGTTTCTTC +GTGCCCCAGATCAACTTTGGTTTTACAGATTAGTTTGCATATTCTAGAGTTTTATATAAA +TGGAATTATATAATATGACTCTTTTATCACTTCTTTTATTCAACATAATTATTTTGAGAT +TCATTCATGTCATATTTCATTCCACTTTATTGATGTGTATTATTCCATTATTTATCTATT +CACCTATTGATGGACACTTGGGTTGTGACCAGTTTTTGGCTATTACAAGTAATGCTGTTA +TGAACATTCATGTACAAATGTTTTATGGGCATATATTTTCTTTGAGGTAAATACCCAGTA +GTAGAATGGCCGAATCATATGGTAAACATAAGTTTAACTCTTTAAGAAACTGTCAAACTG +TTATCTGACTTAGTTATAATACGTTACATTCGCACTCACAGTGTATGAGAGTTCCAGTTC +CTCCACATCCTTCACCAAATTTGGTGAGGGTCAGTCTTTTTAATTTTAGACACTTTAGTA +GGTGTGTAATGGTATCTCATTGGGATTTTAATTGGCACTTTACTAATAACTAATTGCATT +GAACATCTTTCATTTGCTTATTTGCCATATATCTTTCTTGGTGAAGTGTCAGTTCAAAAC +TTTTGCTCATTTTAAAAATTGGGCTGATTATTTTCCTATTATTGAGTTCAGAAAGGTCTT +TATGTATTCTGGATGCATATTCTTTGTCACATGTATGCTTTGCAAATATTTTATTTCAAT +ATGTGGATCTCCCAATTTATCTTTTCCTTCTCTTAACATTGTCTTTTGAAGAGTAGAAGT +TGATCTAGGTGTGTTCTTTATGGATCATCCTGTTGGTGCCACATCTAAGAAACCTTTTCC +TAATCTAAGGTCACCAAGACTTTCTGCTATGTTTTCTTGTAAAAATGTACAGTTTTAGGT +TTCATATTTAAGCCTATGATCAGTTTTGAATTAATTTTTGTAAGCGATGAAGGTATGAAT +AGTTCAGTTATTATATGAATATCTAATTGTTTTAACAGCATTTATGGAAAAGACTATCAT +TTTTCCACTGAAGTGTCTTTGCATTTTTGTCAAAAATCAGTTGTGTATATATGCGTGGCC +TATTTCTGGATGCTATATTCCGTTCTCCAATCTATCTTTATACCAGTATCACACTGTTTT +AATTACTGTAGCTTTATAAGTCTTGAAATCAGGTAGTGTTAATCTTTCAGCTTTGTTCTT +TGTAAAAATTGTTCTGGCTATTCTAAGCCCTTTACATTTCCATGTAAATTTTAGAATGAG +CTTGTCAATTTCTTAAAAAAAAAAAAAAAAAAGCTGCTGAGCTTTTCTCCAAAGGAGAGG +ATTACTTGAGAGTGCGTTGAATCCATTGATAAGTTTAGGGAGAATTGTCATTTTTTTTTG +AAAATTTTTTTCAATTTTTGTCTCCATAGGTTTTAGGGGAACAGGTGGTACTTGGTTACA +TGAGTAAGTTCTTTAGTGGTGATTTGTGAGATTTTGGTGCACCCCTCACCCAAGCAGTAT +ATATACACTGAACCCAATTTGTAGTCTTTTATCCCTCACCCCCCTTTCATACTTTCCACC +GAGTCCCCAAAGTCCATTGTATCATTCTTAGGCCTTTCCATCCTCTAGCTTAGCTCCCAC +TTATGACTGAGAACACAAAATATTTGGTTTTCCATTCCTGAGTCACTTCACTTAGAATAA +TAGTCTCCAATCCCATCCAGTTTGCTGCTAATGCCATTAATTCATTCCTTTTTACAATAT +TGAGTCTTCTGGCCCATGGACAAGGTATATTTCTTCAATTATTTAGATTTTCTTTAATTT +GCCTCAGCAATTTTATTTATTTCTGTATAGGTTTTGCACATATTTTGTCAAATTTAATCG +TAAGTATTTTATTTTTATGCTAGTATAAATGCTATTGGCTTTTATTATAATTTTCAACAG +TTTGTTACCACTATTTAGAAATACAATTGATTTTTGTATATTGATCTTATATACTGCAAC +CTTGCTAAATTGACTTATTATTTCTAATAGCTTATTTTAAATTCTTTCAGTTTTTTACAC +AGACAGTCAGAAGTGGTGAGAATGAGCATCTTTTCTTGCTCCTTACATTAAAAAGAAAGC +ATTCTGTCTTTGACCATTAAGTGAAATGTTAAATATAGGTGTTCGTTTATCATTCTGAGG +AAGTTTCCTTCCATGCCTAGTTTCCTGAGAGTTGTTATCAGAAATGGATGTTGAGTTTTG +CTAAATGTTTTTTGTGTGTCTTTTGAGCTGATCTTGTGGTTTTTCTTTCTTAGTTTGTTA +ATATGGTGAATTACATTAATTCATTGTTGAATGTTAAAACAACCCTGCATTTCTGGAATA +TACACACTTTACTTAGTCATCATGTATTATCCTTTTTATATATTGTTGAATTCATTTTGC +TAAATTTTTGTTTAGAATTTTTACATCTATGTTTATAAGGGTTATTGGCCTATACATGAT +AGATTCTATAGCTAGTAAAAGGAAAATTAGGAAATATTGTGAACAATTTTATGCCTTTAA +ACTTGACAACTTAGATAAAATAGACAAGATTTTTTGAAAGATACAAACTACCAAATCTTA +CTCAAAAAGAAACAGACAACTCAAAAAGCCTCATATTTATTAAATAAATTGAACTTGTAG +TTAGACATCTTCCCACAGAGAAAAGTCCCAAGGCCAAATTCACTAGAATCAGTAGTGAAT +TCTACGAAACATTTAAGAAAGAAATACCAATGCTACACAAACTCAGCCAGAAAACTGAAG +AGGAGGGAATACTTTCTAAATCATTGTCTGATGCAAGTAACAGGCTGGTACCAAAACAAG +ACAAGATCTTTACAAGACAAGCTGAGTATTACTTATCCAAAAAGCTTAGGACCAGAAGAG +TTTCAGATTTTGGATTTTTTTTATTTTGAAATATTTGCATTATATACTTAATGGTTCAGC +ATCCCTAATATGAAATCCAAAATACTCCAATGAGTATTTCCTATGAGTGTCCTGTCAGCC +CTCAAAAACATTTTAGACTTTGAAGCATTTCAGATTTGAGGTGCTCAACTTGTAGTGTAT +CACCTCTCTCATTCCTTATGTAGATAATTTGTGTCTTCTTTTTTCTCAGATCAGTTTAGC +TAGAGATTCAACTTAATTTATCTTCTCTAAAAACTATCTTTTGGTTTCATTGATTTTTTT +ATTATGTTTATTTTTTCTATTTCATTGGTTTCTGCTTTGGTATTCATTAAGCATACTTTG +GGCTTAATTTGCTCTTCTTAATATGCTTTTCGTTTTCTAGTTTCTTAAGATGGAAGGTGA +GGAAATTGATTTGAGGCTTTCTTCTTCTGTAATAATATTGGAATTTAGTGCTATAAATTT +CCTCCCTAAGTACTGTTTTAGTACTGTTTCAAAAATTTTGATTTATTTTGTCAGTTCAAA +AATCTCAAAAGGGAAACTTTTTGAGATTTAATTTGACCTGTGGTTTATTTAGATGTATAT +ATTTATTTACCTAATATTTGGGGATGTTTCAGACATTTTTCTGTTATGAATTTTCAGTGT +AGTTTCATTATAATCAGAGAACATACATTGTATAACTTCATTTTAAATTTATTTCAACTT +ATTTTATGGCTTAGTAAATGCTCTGTATATACATGAAAAGAATGCATAATCTGATGTTTT +GGGGTGGAATGTTTTAAAAATGCCAATAAGATCAAGTTGGTGGATAGTGTTGTCAAGTCT +ACTATAAACTTGCAAATTTTCTATCTACTTGTTCTATCAATTACTGAGAAAGGACTATGG +AAACACCTCGCCATCATTTTTTTTTATTTGTCCTTCAATCAATTTTGCTTAATTCAATTT +AAAGTTCTGCTTCAGGAAGAATAAACGATTAGAATTATTTTGTTCTTTTCATCAGTTAAA +TCCTTATTATAATTAAATAACCTACATTAACTCTGGCAATAGTCTTTGCTCTGAACCCTG +CTTAGTCTGATATTGATATATCATTCCAGCTTCCTTCGGGTTAGTGTTAGCATGATCTAT +TTTTCTGCACCCTTTTCGTGGGCAGCATATAACTCGTCTTGTTTTTGTTTAAATATCTAT +CCTAATTATAGTGTTTAGATTATTTATACTTAATGTAATTATTGATATCTTTAGACTTAA +AGGTAATATCTTGCTATTTATTTTCTACTTGTCCCATTCTTATTGTTCCCTTTTCCTCTT +TTTCTGCATTTGTTGGGATTAATGGAATTTTTTAAATGATTCCTTTATATCTCCTTTGTT +GGCTTACTAGTCATTTTTCATTTTTTTAACTTAGAATTGCTTTAGAGTATATAATATATA +ACTATAATTTAACACAGTCTAAATTCAGGTGATATCATACCAGTTCAGATGAAATATAAC +AACCTTACAATAGTACTTCCATTTCTCCCCTCTCAGACTTTATGATTTTGTTTTCACATG +TTTTACAGATATATATATATCTAATATACCTCACAATATATCATTTTTGTTTTAACAATT +ATCTTTCAAATAACAGATAAAAACTTACATATTTACTCACATAGCTACCATTTCTTGTTC +TCTTCATTCCTTTGTGTCTAAATGCAGAATTCCGTATGTTATCCTTTTTTTTTTTTTTTT +CCTAAAGGACTTCCTTTAACATTTCTTGCAGCACATGTCTGCTGGAAATGAATTCTTTCA +GCTTTTGTATGTCTGAAAATGTCTTTATTCAGCCTTCTTTTTTATTTTTTATTTATTTAT +TTTTTTTCAAGAGACAGGGTCTCACTCTGTCACCCAGGCTGGAGTGCAGTGGCACAATCA +TAGCTCACTACAGCCTCAACATCCTGGGTTCAAGCAATCCTCATGACTCAGCCTCTCAAG +TAGCCGAGACTCCAGGCGTGTGCCACAACATCTGGCTATTTTTTAAATTATTTTTTGTAA +AGACAGGGTCTTGCTTTTTTGCTCAGGCAGGTCTCAAACACCTGGCTTCAAGAAATCCTC +CTGCCTCGGCCTCTGAGAGTATTGGGATTACATGCATGAGCCACTACACTCAGCCACAGA +CTTCTATTTTGAAAGATATTTTACTGGGTAGAGAGTCCTAGATTGACGTGTTTTCTGTTT +TTCTTTTATTACTTGGAAGATTTTACTCTACTGTCTTCTCACTTGGATTGTTTTCAAAAA +GAAATCTGTGTGTAACATGTCCTTTATTCTTCTGTTGCTTTCAAGATAGTCTGTATTGCT +CGTTTGGGGCATGTTTGTTTAAGATGTGCTTGGTGTAATTTTATTTATTTATTTTTATTC +TTGAGGTTCATGACACTCCTTGGATTTGGTAAAGTCAGAAAAGTTTTGGTAATTATTTAT +TCAAATATTTATTTGGCCCACCCATCTCTCTCTCTTCTCCTTTGACTATTCCAGTTACAC +ATGTCTTAGGTGACTTTACATTGGCATGCAATTCACTGAAGCTTTTTGCATTTTTAAAAA +TTTTTTTTATCTTCTCTATGTTTCATTTTAAACCATTTCTATTGCTGTGTCTTTCACTTC +ACTAATCATTTCTTCTAATTTCATTCAGTGTATCTTTTTTTACAGAAATGTACTTTTTGG +CTCTAGAAGTTCAATTTGGGTCTTTTAAAAATATATATCTATATATTCTATTACTTTAGT +TAATGTTTGAACATATAGAATACAATTATAATAATTGTATATAACTGTTTTAATGTCCTG +TCTGCTAATTCCAATATATGTGTCAGTTTGGAGTTGATTTCAGTTGATTATTTGTGTCAT +TTTTCTGCTCCTTTGCATGACTGGCAATCTTTGATTCTATAATAGGTATTGTGAATTTTA +TCTGGTTGAGTGTTGAGCCTTTTTGTATTTTTATGAATATTCTTTAGGGTTTTTTTTTCT +GTGATTTATTAAGTTATTTGGAAACTGTTAGTCCTTTCGGATCTTGCTTTTCTGACTCGT +TCACAGTAGTCTAGGGTTAATTATTCCTCATTATTGAAGCAAGACTTTCCTGATTATCTA +CTCAATGCCCTGTGAATTAGAGATTTTCTAGTCTGACTAGTGAGCACCGGCACTATTCCT +AGCCTTGTGTGAATACTGGGTGCTTTTCTCTAATACTTTTGGAGGTTTTTTCCCTGCCTT +CATGTAGTTTCTTCATACACATACACTAACAAGTACTCTGCTAAATCGTTCAGGGGGACC +ATGTACAGATCTTCAGTGTTCTTTGTGCAATTCTTTTCTCTCCAGTACTTAGCCTTGACT +CTAGCATCCTCAGTCCCCTGAACTCACCTCAACTCCTTTGATCCGGGAGTCTAGTAGCTC +AGCCTGCGTTCCTCCTTTCTACACTCTGGCAAGCTAAGGCAGTCATTGGACTCATCTCAT +TTGTTTTCTGCCTCTCAGAGGCAATTGTCCCTCCTTACCTGATGTCTTAAAAACGTTTCG +TATATTTTGTTTTGACTTGTTGTTGCTGTTGTTTCAGGTGGGAGGTTAAATACAGGTCTT +GTTACTCCAACTTGGTTGTAAGTAGAAGTTCTTCTGGAATCCTTCTTCTTAATTAATATT +TTTTCCAGTGATTACTGACATGATCTACAGGGTACTATTGATCAGCTATTTTTAAATGGC +AGATTCATTGGCTAAAGTGCCCTTATTGGATATGAAAGTTATATATTATTATGTTTTAGT +CAAGAATGTTGACTTATCTTTTGATTCTGACCCAAAAAGGGATTACAACCCACAATGAAA +CCCACTTTAGTGCCTCCACCTTCAGGTCATAGATTGATCATTTGACTGATAATTGATAAT +AAGCAGGATTTTTAGCTACCCCAAGAGGAAGTAAATATGAAGTTCACCATGTCAGACATC +AGACCAGCTCAGAATCATAGTCTTCTTGGTATTCACACTTTTTTGCTCTTTTAACTGTTT +TTCCTGTGCTTTAAATTCTTGTGCCTAACCACCTCATTCTTTCTGTTTACCTCTTCCTCA +TTTTGGAGAAAGACAGAGAGTAGGTGACTAGTCAGGACATTTAATTATTAATCAGTTGCT +TCTAGCTCATATCTGCCTAGAAAACAATAATAGTAATGATAGTAATTTGCCAACATTTAT +TGAGCACTTATATTGTGTTAGGAACTCCTATAAGCACTTTACTCTTATTGACTTATTTAA +TCATCAAAACATATAATAATATTGCTATTGTAGGCTGGGCGCGGTGGCTCACGCCTGTAA +TCCCAGCACTTTGGGAGGCAGAGGTGGGCGGATCATGAGGTCAGGAGATCGAGACCACAG +TGAAACCCCGTCTCTACTAAAAATACAAGAAATTAGCTGGGCGCGGTGGCGGGCGCCTGT +AGTCCCAGCTACTCGGGAGGCTGAGGCATGGGAATGGCGTGAACCCGGGAGGCGGAGCTT +ACAGTGAGCCGAGGTCGCGCCACTGCACTCCAGCCTGGGTGACAGAGTGAGACTCCGTCT +CAAAACAAAACAAAAAAAAAAACAAAAAAAAAAAATTTGCTATTGTATTTCCATTTTACA +GATTGAGAAGCAGAGGCATTAAGAAAATTGTCCAGTGTTGTATACCCAGTTAAAAAGGCA +AAGGATCCCAATCAGGAAACCCTGTGAGGAGCCTGAGATCCTACCCACTCTGCCGTGCCA +CCTTATGCCCAGGCTCCCTCAACTTTAGAATTTACACTGGCCCTGAATTTTGTTTTGTTT +CTGTTTTTTTGTTTTCCTTGAGTTTCTTACATGCTTTTCTCTGACTTTTAATTTGTATGA +CATGGAAATTTTTAACCTAATTGCTGACATAGTATCTCGAGTGAACCTTACTGGATAATT +TCTTGGCTTTCTTGGTCCCAGCTTCCAGTCTTCTTTTGCTGCCCCCCCAGCCACCAGCCC +CAGCACATGCAAGTGTCCCGTCTTCCCCTACTGTTTATGTTCACAGCTCTGTTCCTTTGT +AACTATCTGAATAACGCCTCTTCTCAAATGAAGATCACTGCCTCTGCCTACTTATTCATT +GACTCAGCAGCAGAGCTTCATTTAGAGTAACATAGGAAAAGCAGGGAGTTGCAGGTCTGC +AAAGGGGGAGATTAAAGTGCCCTGAGCCTGATATGTGTGGCTTCAGGGTCCCCCTGACTC +CTCTTCCTGGCTTACATGGGGCCAGTTGAGCTGCTTGTCACATATCTGTTTCCCCCAGTT +TTGGACACATACTTCCTTAAAACAAGGTTGTTGAATTTAACAACACTTGATGGAAGCTTT +GGGGAGCACTGAATACTAAACTGAGAGTAAGTGACTAGTTTTAAGGCCTCACATTGAACC +TCCCAGGAGGCATCATGCAGTAGTGATGTGGCCAGGAACGGAGGATTATCTCAGTCACCA +CCACACCTCCAAGCTCCCCACTGCCTGGCTCCAGAGAAAGAGAAGAGAACTCCTTTATCC +CTCTAAAGCCCACCTAATTTCCTGCCTGAGGATAATTGTCTGAGAAGATTCTATTTCTTT +AAGGGAAATTCTCACATCTACCCAGAGAATGCAGCCAGACCTCCTGGCCCAGGAGAAAAA +CAATGGCTCTGTTCAACCAGTACATTTAAGTCTGTCGAATCCACCATAACTTCACCTTTG +AGACAGCAAAATTCAGTCCTGGTTGTGTGCACAAGCTCAGTCTGGTTCCTCTTCACAGCA +TTTTCTCCAGTGAGAGGATAAGAGATCAGAGCACCACACTCCTCCTTGTGCCCTGCACTC +TTCTTATTTCCTATGAGCAAGTGCTTGGGCAAAAAGATGCATGTATCTACCAAGGACAAG +TCAGCATTTTCAGGAATAAGGCAGCATACATTGCAATTTACTGGGGAATCTCCCTAGACG +TGTGGATGTGCAAACGAGGCATCAGACTTACGTCACTAACCAGAAAGCTTACCATCTCAA +GCTGAAGTCCCTGCACTTGGCTATTTCACAGGATCAGGGCATTCCCAACAAGAGTGGATA +GGTACTTGCATTATATATTGCATAAAGGAAAAGTTCACCAAAGTGATTTTCAGAACTAAG +GTAGACTTTGCCACACAGATCTAATCCAATGGTGATGTTGCTGGCAGAACTGCCAATCGG +TTTCATTAACACTAAAGTACATTTTTACCAAATAAATGTCCCTATTTAATGTAAGTGCTT +ATATTTAGAAAAGAAATGAGAAGTGGAATTATTTTACGTGCTTGCAATGTAGAAACCGAA +GCTCAGAGAAATTAGACAATAGGTCTAAACCAACCCTGTGCTTCCCCAAGTGAAATAACA +CCAGGTTCATGAGGAACTCCTGGGTCAGCAGCAGAAGCACTCCTTCTCCCAGCCTCAGCA +CATTGCCTATGACCCTTGAGGATGTTTCTGATGAGGTGAAAGACTGATCGCATAGCCAGG +GAAGAAGATATATCCAGAGACCTGGCCAGGTGATTGCTTTCGGCAGGGAAAGAGCCCTTT +CTAAACAAGTGACCGGAATGTAAAAATCAGGGTCAGACACTTCAAATCAAATCATCCACA +AATGCAGAAACCAAGGATGGATACACATTGGTCTTGGTTAAAAGTAGAGACTCAAATCTG +GGGTACTTGGGGATGGGGGAACAGCCTTGGAATGCAGAGTCACAGCCACGGGAGCTGGGA +ATGAGTTTGTTAAACCTGACTCACCAATGATGGAGGGCAGAGCTGGGTATGGAGCCAATG +TCAGGCTCAGGAGAAGAATGTCGAGGAAGGAGAAAAGCCCAAGGTACAGGTTCACAGGTC +AGGACAGACTACAGACAGAGAGGCTGGTCTGGCATAGCTGAGAGTGTCTTGACGGACTTA +AATCCCTAGAGCCACCCTTGGAAGCACCTGTTCCTCCTGGCTCAGTCTGGCGGGTTGTGG +GGCCAGTCTGCCTGCTTCCTGGCAGGGTCCTGACACCAATCAATGGTGACTGCACAGTCC +CCCCACACATGAAACAGAGGGCACTCTGTTAGGCAGATTCACTGTCAACCTTGTATCTTA +CTCTTTGTCATAAAGCTCTTGTGTTTACCACTGCATTAAATATAACCCTGCAATAGAAAA +ATCCTCATTTTCATGCTTGAAATACATTATCTAATGGCATATCTATTTGACTTTTACTAC +ATGCCTTTCATTCCTCTGAGGTAATTGACCTTTACTTTGCTACCCTGTGGATTAAAAGGC +TACCACACACTCTGCATTTGATATTTCCAGTCCTGCAGGAGAGGCAATTTCCATTTGCTT +TTGTTGCAAGGCTGCTCTTCAGGCGGGTCCTCAAATGAAGGGAAACCTCAAGGTCTGGAA +CTGCATCGTGGCAGTTATTGTCAGCATCATGTGGTTTTTATTTTAAAAAGCACATGTCGC +TTCATTTCTATGGTCATCTCTACGGAATTGTAAAGACCTATAAGACTTCCAGAACCTTCC +ACCTTCGTTTCAGATGCTATATCCTCACTCTCTGAGGATCAGGGATCAACAGTGGCCTTC +AGATTTGATTCAAGCACCTGAAAGTTTAAAATTGTGTCCAAACTACACAATTCATGAGAG +ATAAAAACATGAATGGTATTAGTCATATCCTAAGCTGCCAGCCATATAGATCCAGAAACC +TTTCATGTGATAATTTAGCAATACTGTTACAAAGAACTCTGCAAGTCAGGAATTTGGAGA +TCTTGGCTTTCTCTAGTGCCCTATCAGCCCTCCTTCCCACAACCAAAATAATAACAAGAA +TAATGAAGGTGGTAATAATGATAGCAAGCACTATGTGTCAGGTACTATTTTTTAAATACT +TCAAAGATAATAATTTGTTATTCTTAACAACCTAATAATGTAGGTACTGTTAAAATCCAG +TTTTACAGATGAGGAAATTAAGATACATAAAAGTTAAGCAACCTGCTAGCAGGTGGTAAA +GCAAGTGGAATTCAAATTGGAGCATTTTGGACTTGAGATAGAAGACCAGGATACAAGAGA +AGGAAAGAACATCAATAAAGATGCTATTCTCAGAACTATCTCCCTGGGGTGGGAAAAAAT +ACTGGAGTATTTATCCTCAAACATCTGTTTCTTTGAGAGTTGCTCCTGGGAAGTTAAATC +ACCTCTGGCCTGTTCAACTTGACTGGCCAAGCATCAAGCATGTTAAGGCAAAAGGCAGAG +ACTATGAAGCTGACTGTTGGGAGAACTGTCTGCAGTGACCTTCAGGGGAGGCCACAGGAA +AATTTGAAAGGCAATGATGCTACCCACTTTTTATTTTTTCAAGCACAAAACCCTAATTAA +TCTCTCTTTTTTTTCCATCAAATGATTTTTGATAACCTGTTAAAGCCATAGCAGAAATTT +TTGGCAAATAAAGCAAGGCAAAGTGATCTCCATTTTCAAACACTTAAAAGATGAAAGTTG +CCTTACTTTGTTTAAAGTATTGCTAATAGGACTTGGGGGAGATGGGAGAAGGAGGTGTGT +GGAGAAGAGCTAAGTCATTATGTTATCACTTTAAAACCAGTTTGGCTTTATATTCTGTTA +CACATATACTCCCTAGGGATGATTTTTTTCTTTATCTGTAAAATAGGGATAGTGATACTT +TCTTGTATCTCTCTCATAAAGCTGCTGTATAAATGAAGTAAAACACCATTACACTGTTAG +GAAAATGTATTCTTATGAAGGCATGTTTAAACATGAAGTAGTTCAATAGTGCTAGCTAAT +TTACTATTGTTATTATTATTTCTCTGATCCTGGTTTTCATATTTCCACAGCGAGGAGATA +GAATTAGATAATTTTTTCCAGCAAGTGTTTATTAAGAGCTTACTGCACACCAGGCGCCAT +GGAAGGCCTTGCTCAGGACCTGGGGATTCAGCCCTGCCTGTCCCCTGACCATACCCTGAC +CATCCCCTGCTGGTCCCTTACCCTCAAGAAGCTCATAGTCCTGGTTCCTTTCCTCCACAC +TACTGTTAAATATAAAACAAAACACTTCTGTTAAATATAAAACAAAAATATTTAACACTT +CTGTTAAATATAAAACAAAAATGAGAAAATCTGATGACCCTGGAGTATGAGTTGAAACAT +CAGGTCCCTTTCATCTGTTTGTTTTGCTTGTTCATCAATGGTTCAATGCTCAGAAATAGT +AAAAACTTAACCACAGGGTCCTCTATATTGTGAGTATTAAACAACTATTTTATAAATGAT +TGATTATGACATCAGATAGGACCTAAAACTTATCAAGTACCTACTCATGTGGTGTTGATG +GTGGCACTTGACATGTTATGTCATTCAAAAGTCACAATAAAACCAAATGAAGAGCTTATT +GTCATCTCTATTTTACAGATAAGGAGCTAGACCTAGAGAAGCAAAGTCACTAGCCTAAGG +TCAAACAGCTTTTAAAGTGATAAAGGGCAGAGTCAAATCCAGTTTTCTCTAACTCCAAAA +TATAGCACCTTTCTCTTTAACTAAAAAAAAAAAAAAAAAAAAAAAAAAAAGTCACTTTAT +TTTAACTAATTTGTTTCGTAAGCATTGCATAAGATTAGAACTAGAATGGGCTTTGAAATT +AGCATATTCTAATGCCTGCCTCCTAGTGATATCATTTCTCCATTTTCCAAAGCTAAATGC +TAGGTAGAAAACTCTGGTTGATCCAGATCATGTTTTCAGGCCAGGCCATAAGTTGCAGAT +TGCTGCTCAATCCATTGTTTTGCATCCAGTCTAGCTCATTCAGGTTGGGAGGTGAAGTAA +CGTGATGTACTCTGTGCTGTAGTCAGGTATGTTAGTTAGCATCTTTGGGTTGCAAGTGTT +AGAAAAATAATCCAAACCAGTTTAAACCAAATAGAGATTATTTGGCTTACATAACTAGGA +ATCCAGGACACAGCTAGATTCAGACAGGCTGGATCATGGGCTACATAAAGTCATCAGGAC +ATTGACCCTGGCTCTTGCTTCTGCTCTCTTCTGTCTTGGCTTTATTCTAAGCCGGGATTC +TCCATGTCATGGCCAAAATGATGACCAGTTCCAAGTTTACCTTCTATCAGGTTGGCAGTA +TTGTAATTAAAAGGACTTGTCTCTCCCATGATCTCAGCAAAGGCCCCAGGGCCAATTTTC +ATAGTTGGTTTCAAAATTGAACCAATCACAATGGTTGGTTCAATTTTCCTTGAACCAACC +ATTGTGTCAGGAAGATAGAATGGATTGATGGGCTGAACCTGGCTTCTCTGTTCTCCTTGC +TGGAAGTTGGGAATTGCTTAACCTGAGAATGAGGAAGAGTGGTCCCAAAGGGTTGTTATC +AAAGAAGGAAGAAGGTATTGGGGTGTGCAAAAGCTACAGCATGCAACCTCACTACAACTT +AGATATTGCCAGAAGGTGGGGACAGTCAAGGAGCCAATGTGAGACATTTTTCAACATAGA +TCAAACCCTTTAAATTTCAAAGAAATTAGCCCCAGAAAGCCAGCCCAGCCCAACTAGTGA +ATCAGCTAGTTAGTGTCTCTTGATCGTATATCATTTGACTCTAAAAATGTGACATTGATC +CATGTTAAATTATTTTAAATTTCACTTTTCATTAAAACATTTGTACACACTTTGTGCAGA +CTCCATTTTGGAATATTTAACCAGATAGACAGAAAGATTGCAGGCATTGACTATAATTAT +GACAGTGTCAAGAAGTCCAGTAGTCACTATCTGGTTATTTTTTTCTTGGCCATGTCCTAT +CTGTTGTATCATTTCAGACATCATTGCTGTTCTTCATTTCTCTTTTCAGGGTTCTTTGTG +TCTTTGCTTTAAAACCTTTGTTTCTATTCTTAAGTGGCACAGTTTGGGTCATTGGTCTTG +ACAAATAAGATCAGATTCCTTTGGTGGGCTTGGGTTTTTGGTTTTGTTTTCCCTTTTCCT +CTCTCTCTCTCTCTCTCTTTATTTTTTGTTTTGTTTTTGGTCTTTAAAACTTCAACTTTT +CCAAGGCTTATTAACAAAAGTAGGCCACCAAATAAGAGGAAAAAAAAAAAGAGCTTTGCT +AGGTGCACTCTTCTCTATTGGAAATTATTTTATTTCTCAGAAAAGGGAGAATTAGAAGAA +AGCTATTTTCCCCAATTTTCCATACCACCCATGGGAATCCAATTCAATTTCCTCTCGAAT +TTTGTAGTAAAAACTAAAAGTATGGAATAAAGTTGCTGGAGTGTAGTATTCTTTTACACA +GATTTGATGTTTTAAAATTCTTAGTCATAGAGCTATTTACTCAGCCTGATCCATTTCTAA +TCAGAGTGTAATATAACCATTTGATGAAATAATCTTTTTTTAAGTAGACAAGTATACATA +TTTAAGAGATATCAAAACCTTACCTGATAATCTAGCCTGATAGAAGAGGGCTATGGAGTC +AGATGGCTCACAGCTCTCTAGCCAGAGCCTGCCTGAACTCTGTGGCTTTGCAAAACCCAA +GAGAGCATTAGGTTTATTCTTGCTCTATTTTTCTTTTCTCACAGTTTCCCCTATAAAAAA +TTATATTGTTTAATCCAAGGAAGTATATAAGAAATTATCATGGTATAGTTCACATCAAAT +CGGAAATAAAAACCTAAATGAAAGAAATATTTCACTTATGTGGTTCTATAAAGAGAAAAA +AAGAAAGAGATCTAATATAGAAGTTGGTTACCATAAACCACAGAATGGATGAATATGTGT +GAAAATAGCTTGAATACATCACAAATCTTTATAAGCTCTAGGACTATTTTATTTATCTTC +ATAGCAGTCCTACATTATAGCTAATAATAATAGTCTTGAGTTACACAGAAGGAAGCTGAG +ACTCAGTTGGATGCACCCAGCAGGTTAATGAGAGAGCCAGGACTTGAACTCAGCCCCTTT +TGTCACCAGAGTCCAAGCTCTTAACACTATGTTACCCTATTCCTCTTATAGACTCTGGTT +ACTTGAACGTTGTTCATTTGTATTTCTGGGGCTGGAATACCCTAAACTTTCTGTTTCCTC +AAAAGGACGTAGAATATAAAAGTTTGCCACACCTGTGCATATATTAAGCACCTAGTTTTG +TTAATGCTGTTAATTGCTTATTGGCCTTGGGTTCACTTAGTTTTAATTTAACAAGCCTTT +TGCCTACCAGTCTTCGGATAGATTGGTTTTGTGGAGAACGGTTGCAATCTGGATTGTAGT +AATTATCTTGTTATGTCTTTTATCCTTCAGCACTCCTTATCTAACCAGATTCCTCATGAG +TTTAGCAAATGGTCACGGAGCACCATCATATTCCTGCACCAATCTTGAGCAGTTCATTAT +CTCAAACTTATAAGCTCCTATCTTCATTTTATAGTCATGGTACTCTAGCCTCCCTTGCAA +GCTTAGAAATAGAATAGGGCAACTTTTACTATTATCTAATAGAACCAGCAGTTTACTGAA +TCATGTAATCTGATGCTTCACTATACTCAAGTTTAGAGGCTCAAGTAAGGTTTAAATGGA +ATTTTAGATAATTTTTTTAAATGCCAAGATGTCTAACTCATTTATTGCCTAAATGTACAA +GAAGACTTTCTGGTCCTTGTTCCATCAACTTCTGGGGCAAGCCAATTGCTCTCTCTCTCT +CTATATATATGACCACAGCATCCCACTGTCCATGAAGAAATGATCAAAATCTCAGTTTTT +AGTTTACATTCCCAGAGGAAACTGCATAGCAGTCTATTTCTCTGTTTATTTGTTTTTTCT +TTATAGTCTATACCAGTCAGTTTCCAAAGATAATTTTCTCAAGAACAGAGCCCAAGACAA +GAAAATCCCATCAACCAGGAGCTATATTAGGTACTCATTATACTTGTGAAAGAATGAGCT +CAAGAACTCTATGGAAACCTGGCCTCTGGGTTTGCAGAGAGGCTGCCTAGAGCCCTAATG +CCCCTTCTTTCATGTATGCTTCTCCTATAATACAGGAATTCGTATGCAAATTGGCTGTTG +TCCTCTTTGTTGGTCTGTTGACATGTGGCTGCTTTCAAAAAATTATAAGAAGATATCTAT +TTCACATTAAACTTTGGTCATTGCATATTTTGGAAAAATACATCTTCTAAAAACATTTTT +GCTTAGCAGGGATAACTACTGTCAAACTCTGGGTTTTTATTAATAAAGAATGGAATCATA +GAATGCTGAACAGATTGGAGTCTTCTCTTTCCTCTGGTATCAGGATCAGGCCAGGCACAC +TTGACATTTCATGATCTAGGCTTTTGCTGTAATATTGTACTTAATTATACAAGTGATGAT +AATAATAGCTTATATTTATTAAGTGATTAATATATACCAGGCCCTGTGTTCAGATATCAG +TTGTGGGAAGACAGACTCACGTTAACAGTGCCCTAGGACTGGGATCGTGGCCTCTGCTCC +ATATACCCACTTTGACACACGTTCCCTAATTACAGTGGAAGTTGTCTGAGGGCTGGGATT +CAGTCCCCTCACCGCCACGCCACTACTCTCTGGTCTCTGCCATAGTCCATGTGGTCCTGG +TCTCTGCCATAGTCCATGTGGTCCTGGTCTCTGCCATAGTCCATGTGGTCCATGATGGCT +CCACACTGTGTTCTTATTCCAGGAAATAAATGAGAAATTGAGGAATGAGTTTCACAGACG +CCATGCCTGCTAATACCCCATCGGTCAGAACATAGTCATATGGCCACACCTAGCTAGAGA +AGGTGTTGAGAGGTGTTATCTTTATACTGGTGACTGTGTACCCAGCTAAAACTGTGCTGT +TGTGAGGAAAAAAAAAAAAAAGATTATATATCAGTTACCAGTCTTGGCCTCATTGTGTCA +TATCATTTAATGCTCCTAACAACCCCTTTTGTAGGTATCTTATTATCCTCATTTTACAGA +GTAAGTAAATTGAGCTTAAGGAACTTGCCTAAAACTTCCTGCTGCACAGGGCTACATGAT +TCCAGGGCTGAAACTTTTATCCACTGTTTTCTATTCTATTTTGGATAAATGCCATACTTT +TAAGAATTTTGTTTTTTTTTTTAATGTACAATTCAGTGGTTTTTAGTATATTCAAAATGT +TGTGCAACCATCACCACTGTCTAATTCCAGAACATTTTTATCACTCAAAAAGCCCCTATC +CATCAACAGTCACTCCCCATGTGCCCCTCGTGCCCCTCTCCCCATCTCCTGGCATCCACT +AATCTACTTTCTGTCTCTATAGACTTGCCTATTCTGGACATTTCATATGAAGGAAACTGT +ATATATACATATATATACTTATATGTATGTATATATATATACACATATATATACTTATAT +GTATGTATATATATATATGTGTGTATATATATATATATATTTTTTTTTTTTTCTTCCTTT +GAAATGGGGTTTCACTCTTGTTGCCCAGACTGGAGTTCAATGGCATGATCTCGGCTCACT +GCAGCCTACACCTCTTGGATTCAAGCTATTCTTCTGTCTCAGCCCTCTGAGTAGCTGGGA +TTACAGGCGCCCGCCACCAGGCCCAGCTAACTTTTTTTTGTATTTTTAGTAGAGATGGGG +TTTCGCCATGTTGGCCAGGCTGGTCTTGAACTCCTGACCTCAAGTGATCTGCCTGCCTCG +GCCTCCCAAAGTGCTGGGATTACAGGCGTGTGCCACCACTCCTGGCAGGAAATCAGATAT +TACGTGGCCTTTTGTGTCTGACATTTTTCACATAGCACAATGCTTCCAAGGTTAATTCAT +GCTGTAGCATGTATCAGTACTTCATTCTTTTTTATGGCAGAATAATATTCCATTGTATGG +ATATACTGAATTTTGTTTATCTATTCATCAGTTGATGGACATTGGGTTGTGTTCACTTTT +TGGCTATTATGAATAATGTTGCTTTTAATATTTGCGTACAAGTTTTTATGTGGACATATT +TTCAGTTCTCTTGGATAAATACCTAGATGTAAAATTTATGGGTCATATGGTAACTGTATC +TTTTTGAGGAACTGCCAGACTATTTTGCAAAATGGCTGTACCACTTTGAAAGTGTAAAAA +CACATTTTATACTCCCAATAGCAATCTCTGAGGATTCCAATTTCTCCACATCCTTGCAGC +ATTTGTTATCATCCATCTTTGTTTTATTACAGCCATCCTAGTGTGAATCGGCGTCTCATT +GTCATTTTGATTTGCATCTCCCTTAATGACAAATAATGTTGAGCATTTCTTCGTGTGCTT +ATTGGCTATTTGTATATCGTCTTCTTAAAATATCTATTCAGATTCTTCACCCATTTTCTA +ATTGGGTTATTTGTCATTTTATAAATCAGTTGTTAGCATTCCTAATATGTTCTAAACATA +AATACCATTTTAAACAGTAAGTGCAACCCATTTTGATATAGTTAAATTGTTCAGTTATTG +TATGAATGCACCAATTAGTAGATTTGACAGAATTTCCAAACAAAATAATCAGTCCAGTTT +GTGAGTACAGCTAGAACCTTAGTGCTAGTCCAGTTTGGGCCAAAAATTTTATTCTGGTAG +AAGGGAGAGGGCTTGCATAAGCCTCAGCCATATTTTAGTTTTTCTGTTCATCAGAACTCT +GACATACTGGTGAGCTCTACAGTGTTTCTCAAAGCTTACTGTGCATCTAAGTCATGTGAA +ATCTTGTTAACGTTGCAGATTCTGCTTTAGTAAGCCTAGAGGAAGCCTGGGATTTCTAAC +AAGCCCTCTGCTGATACAGAAGATGCTGGTCCATGGACCACACATTGATTAGCAACATTA +GAGTATTAAGTGTTAATGTGGCTGTCTAGAACCTTGAGTCTAATTGTTATATGAACCAGA +TTGCTTAGTTCTAATCTCAGAGAGAGTAATGTCCTAGATCCAGCCTTTGGAATTGACTCT +TGGCTGCCACTTACCAGCAGTGTGTTTCTTTGAGCAAGTTACTTTACTGCTCTCAGCCAC +ACATCTGAAACTAACAGGTAATTATACCTCCTTCTCAGAGTGATAATGAGGATGAGGTGA +AATAATGTACATAAAGCATCTATTACAGTTCCAGGTATATGAAGGGCCTTGGTAATTGTT +GGCCCTCTTTTTTCCACTTGCCTTCCGTAATAGAGACTGTCTCCCTCTGATTGTTCAGTG +CAAAGGCATCATCATCACTGGAGAGACAACTAAGTGTCCCTACCCTACTTTGTTATATTG +TCATGATTAGATACAGAGAGTATTACTCTGTTTATAGTCTGTAGTTATTCTGTGTATGTT +TCATCTTCTCTACTCAACAGATTCTATGTTCTTGGGGATTAGGACTATATATTGCCTTCT +GTTTGAATCCCTATGCGACCTCTCATGGTGTATCCATAGACTATCCCATTAATTAATGCC +CACAGAATGAATCAGACAGCCCAAGTCCATAGTAGTAGAGATAGTAACTATAGAAATAAT +AAAGGAAACTAACATTTGTTAAGAACTTTGTGTCAGATACTATCTTAAGGGCTTACATGC +ATCATCTGGTTCAAGCCCCACAACCGTCCTTTGAAACCCCTCCATTTCTTGCCCTTGTTT +TACAGAAAAGGCAGCTGAATTTTAGCTGTACTCAGCAAGAGTGAATGCCCTCTGCAGTTG +TAAGAGCAAAGTTCTGGAGGCAGGCTGCCCATGGTCTAAATCCCTGCTCCATTTTGTACC +TGCTGGGATTCAGAACACTTTAATATTCAAATGCATGATCATCTGTAATCATTAGTGCAG +GTCTCATGGGATTGTTGTGAGCTTGGTATGAAACAATATGTGAAAAATGCAAAAAGCAAT +GAGCACAATGCCAGGTGCTTAGAATTATTCAGACAATGGTAGCTTTGTTTAGTTGTTGAT +TTGTTAAGTTACTTATCCTGGCCTTACAGTAAGTAAGTGGCAAAGGAGGGATTTGAACTC +AGGCTGTCTATTTCAGTGTCCCAGTGTCATAACTCATCAACTCTAAGTTATGTTGTTGCA +CATCTCCCATTTCAAGTAATGTGTTAAGGTGGGAACTGGAAATTCATGTGTCTATGTAAA +GAAAGTCAAAAGTCAAGGTGGCTGCAGAGACAGAAAAAGAATGTGAGAGGCACTGTATAA +TGTATCACTCTTTTAAAAAGATATTTACAAGCTCCAATATTTGTGCTAACACGTTCTCTA +AAAGCATTTGTATAGCTAGTGCCAATCCAAGGGAAGAGGCGCAAGCAGAGGATGATCCAC +ATTTTGGAATGCCTAAAACTTACTTCCTTTGGGGATGCAGGGACCCAAGGGGCCTCATTA +AGGAAAAACCCTCATTAATAAAAATAAATAAATATCTTACTTGAGTAAATTATACCAAAG +CATATTACCATGTGAACATATTGCTAGGGTCGTCCTCAGAGCCCTGAAAGGGCCCCGAAG +CTAAACTTCATCCACTTCATGGTGAATCCTCCTATGGCACAAAAGTAACCAAAACTCTGA +CTGCACAACAGGAAGCCTGGCCTGCATTCATGTTTTTCTTCACAAAGGGACATTTTTTTA +ATTTCTTTGTCTCAGTACCTCTATTTTGAACATTAGTAATAGGCTATATGGACCTCGAGC +TCACAGGAAATTCTGGCAGATAACAGGCTTCCCAGAATAGATATATTAAGTTATAAAAAA +ATAAAAAAATGAGGCAGACGGTATAGGTTTTTCATACCTACTGGCAGGTGGCACAGAACT +AAATGTTGGAGCATTTTTATAAGCAAGATTAAATTGACTCATGACAGCTGGTCACTAAAA +TACAGGAAGTGCAGATCTGGTTGAAAGCGAGAACACACTGGTGTTCGTAAAGTTTGCATC +ACAGACTAGAGCTCACTTTTTCTTTTAAGTCTGCCTTAGCGACACCCTTATTTGGCAATG +TCTGCCATTTATCACTTGCACACAAGTAGATGTTCAAGGAACACGCAGGTCAATTAGTTC +TATCTGCAGTGCTTAGGTATGAGTACTGTGGGTGTAAACAGAATCGGTGAATAGACTTGG +CTCTCGAGAACATCAGACATGTGACTGCTAGCAGAGCCTTTTCGGTCTCCACTTGTCCAG +TCCTCCCCTGCCTAAAGCGACAGGATAAATAGACGTGGGAGCTGGATGGCCATGGGAATG +GATAATGAATCTGTCAGAGACAAGTGGGACGTCACAGAAGTCTGCCCTCTACACATCGTG +AGGCCGGAGGTCACAGCACCAGGAATTGACAGCAATCTCCCAGCATTGTGAAATGTTTTT +GTTTTTTTGTTTTTTTTCTGGCAAGGGCTCTAAATCACAGGTTTTCACATCTGATTGGAA +TGGGGCTGGTGAGGATAAACTGAGTTGTGGAAAATGAAAGGGAGTCCTCTCCAAACAAAG +GAAGTGCCCTGGTGCCTCACCCTCTACTTGCAGTGTTCAGCCCCAGCACAGCAATTGTTA +CACTGACTAAGCAAAGACAGCCCAAAAGCTTCACCAGATGTGAAGTTACAGTTTTAGCCA +ACGTTCAAGCAATGCCCTTCCTCCAACTTCAGCTGGACCAGGGTGGCCATCCTTGCATGA +GACATTAAAGCTAAAAGAGGCACATTTCAGAATAATTACGCTATGCAAATGCTTTGTTTT +TTTCTCTCCCCTGAGCTGTGTTCTTTTCCTAGGTCTTTCAAACATTGTTTAAGAAGCTCT +TGTTTTGGGTTTCAGTCATCTGATGAATCCCCTGGAGTTTAAATGAAATTAAACTGGGTT +TATGATATCTCACAAATTTCATAGCGTCTCCTTTCTCCAATGTAGTGTAAGTTATGAAAA +CCAACAATTAGGGCATGTGGCAGTTTTCAACACACATCATGGAGTGTTTAATTTAGTACA +ATGTCTATTAATTTTTCATTAATTAGTCCATTGTCAAATTAGACACAGTAGAACATGCAT +ATGACATTCCTGCTTTCAGGAAGCTTACTTTATTATCATTTGTCTTAATCGTCTAAGTTT +TCAAGCACTTATTATGTGCCAAGAACAGCAACACACACTAGGGATATTACAATAAATAAA +GCAGACATGACTGCTGCCTCCCAGGAACTTATCCTCTAGTGAGGATGACAGAATAAGCAA +TTAAAATACAGTCTACAGTCTATAGCAAAGATGCTATGGGTTTTATTATGCAACCAGCCT +TGCCTTATGTCATAGGAGCACACAGAAAAGGCATCCTGGTGGACCAGAGAAACATTCCAA +CTATGGGCAGATATTTTTTGTATACCAGAAAGGAGCCAGCCACTGACATATACAGGTTAA +TATCTGAAGGGAAGAATTATCCTGATCAAAGAGGTAGGAATAGGAGAGTAGAATGCTGTA +GGCAGAAGAAACAGCTTATAAGAGTACCTGAAGGCAAAGCTTGAAGAACTAAGTGTAGAG +TTAGGAGTGGTACAAATGAAGCTGGAAAAGGGGCAAGAGATAAATTGCAAAATGAACTTG +CAAGCCATGTAACAGAGCTTGGACTCTATCCTGAAAATAATGGGAAATCTTACAATGGTT +CTATTCCAGAAGTGACCCAAAATATATTTGTGTAAAAAAATATTTGGACTATTGTGTTGA +GATTGGGTAGAGAGGGGCATGCCTGGAGCACAAAATTCTGTTTAGAAGTTCTTGTAATAA +ACCAGATCAAAGATGATGATCACAGCTAAGAAAGTGATTGTTGCTAGAACTGTATGGATT +GGAAAGAGAATCAAGGAAGAGTGCATTAGTCCATTTGCACAGCTATAAAGAAATACCTAA +GACTTGGTAATTTATAAAGGAAAGAAGCTTATTTTGGCTTACAGTTCTGTAAGCTGTGTA +CAAGAAGCGTGATGCCTGCATCTGCTCAGTTTCTGATGAGGGCCTCAGGAAGCTTCCACT +CATGGTGGAAGGCAAAGGGGAAGTTGACATGTCACATGGCAAGAGCAGGAACAAGAATGG +GGGAGGGAGGTACCACACTTTTTAAACCGCCAGATCTTGCAAAAACTCATGGAGGGAGAA +CTCAGTCATTACCACAATGAGGGCACCAAGCCTTCATGAGAGATCTGCCCTCATGACTCC +AATACCTCCCATCAGGTCCCTCCCTAGCATTGGAGATCACATTTCAACATGAGATTTGGA +GGGGACAAAATATCCAAACCATATCAAAGAGGAATCTCAGGGCATGGTGAGAGACTGACT +AATGCCAGATTAGATGTGGTAGGAAAAGGAGAGGGATACATCATTCTTGCCTAACTGGGT +GGAAGATGGTACAATTTACTAAGAAAGCACAGAAGGAAGAATGGGTGAGGCAGGAAGCCA +AAGAGTTTAGTTTGGGGACATATTGAGTTAAGTATGTCCAGGAGGCATTTTGATGAATAA +GTCTGAAGCCTGGGAGAGAGATCTGAGATGGAGATACAGAGCCCAGACTTACCAGCATTT +TGATTAGATATTCTTCATGTGGTGTAATGGAGGGAGGGGGCTCTATGGACCCCAGTGGGT +AACAGAGAATCTTCGAATATCCTAAAGTGTTTTCACACTTTGAGCTTCCTTTAAATATAT +TTATTTGGGGTGGGGAAGATGATGTGAATTTGCTTTAAAAGGTTTGTAATGCGAAGGAAG +TTAAGGAGTGCAGACAAAGATTGAAGGGACAACTAGATAAGAGTGCGCAAGGAGAGTGAG +CTGGCTGTGCTAGGCCAGAACCCAGAGAACAGCATGTGTAGTCAACAGGCTGAAGAGGTT +CCTGAAAACGAGCTTGGGTATCCAGAGGGGAGAGTGTCAGGGGAGAGGGAGTGGTCCAGA +GTCCCAGCCCCTGAGGAAACAAATAAGGCATGGAAAAGTATCCATTGGATTTTCAACAAG +GAGGTCGTGGGTGATTTGACAAGGGAGGCTGTGGACATTTGGAAGGACTGAGTGAGTGGG +AGATGAGAGAATGGAGATGGCAAGTATAGGAAACTCAAGAAGGGAGGGGAGAGGACTTAG +GAGGTAGCTAGAGAAGATGACCAAATGCACAGCAGGTATTTCCTCACCTTAAGATGGGAG +AGGCTTGTGCAATGAGTGAGAAAATTTATAAGTATGAAAAGCCTTTAGTAACAACCTATC +CAAGCACACGGACACATTTAAGGAAATCAGAAGAGTAGAACTCAGGGTTATGTACAGTGG +TCAGGATGGATTCAGGTTATGAATTGAGTTGAGCCTTGAATGGTTAATAAGCTTTAGGAC +AGCTGAGAATGAGCCATTAATTGGAAGAAATCTGAGAAAAAATAAGACTAAACATTCATC +TATTCTCCTTTTACCTCCTTTTATTATTCAAAGAATATCTTCTCAGCTAATATAATGTCT +TTAGAATGGAAATTGCCTGTAACTCAGAGTGACTACAAGTATGAAAGTATTAACAGTTAC +AAGATACATAATCCAATTTACAATTACTCCTTGCATTCTTGATCTTCACGCAGGAAACCA +GCATATTCTTTGGGATCACATTGTTCAATTTCCTCATTTGGAATTTTTAACACCAGATAT +GGTGCTAAATCAGTATAAGCTGGTGCTTCTATCACTTAGGTTTTAAACATCCTCCGTATA +TAGAAACACACCCATAAATAAAGGTGTTAATGTTGGAAGGAGAAAGATGCTTTAATAAGC +AACCTAGCACAAGTAATTCCCTGCATATAGGAGATTATTATAGGACCTAGCTCATAATTA +AACATTGCCTATTTAACTGAATTATTTTTTATCTTACCTTTTTAAGGAATATACAAATGT +TCATTTTCAAAGGTGACATTTATGTGTCTAAGTTGAACAAGCTTATTATAATTCATAAGT +ACACAGAGAACAGATTGTAGCAAGAAGTATTAAACATTGTAATAGACCCCCGAGAAAGCT +GTAGCTTGGTCTTCCCAGACAGGTTTGAGTAGATGGTGATTGCTTTAGGACTACACCTTT +TAGTTAAAAGAGAGCCCAACAGCTTTCAGTAATAGTCTTAACCATTCCTTTTTTTCCTTG +CCGTAAGTATGGGTCAGTGTTCCAGAAAGATTATGGAGGCACTAAAGAAAAACTTGGCCA +TTGCTATACAGACATTAGAGAAGCCAACATGGTTGTTAAGGAGTCTTATCTTCCTACCTA +AGAAAGAGCATTCTGTTCTTTTTCCCATTCATGGCATTTGGCCCAAGAGAAAAATAAAAT +AAAATAAAATACTATAATATTTTTTGGTCTTTATGAAACTTGATTTTCTATATTTTTGTC +CTAGTTCCTGGAAGAGGCCATGTTTCTCTCTCACACACACACACATAAACACACACACAC +ACACACTGTCAATCTCTCTCTCTCTCTGGTTCTGATTCAGACCTATCTTGGTTCTCTACC +CCTGCCCAGGCTGGATGCCCAGGTTCTCTCCTATGTGTGGACCATCTCTTCCCACATACA +TTATTCTGACCTCTGGTTGTGGCCATTCTGTCAATGTAGGTTTTACCTTTCCAGAGGATA +TGGTGTGATACAGTTTATATCCTGCTGCCTCAACAAATATCAAGTTAGCCACTGCAATTT +TATAGTCAAAGACTTCGGGCATTGGGATGTATTTTTGTGGAAATTGCATATTCCATTGTT +GCCTCTCATATATCATGGCTTTATTCATAGGCAGCAAAGGCCAGGCCTTGGCTAATGACT +TCCAAACCCTGCCACATGAAGGATTTTTTTTTCTCCTTTAGGATTCTAGGCATTTTTAAT +TAGAGTCATTTGGCCTGTTTCTGAGAGCCCTTTGTGATTCTCCGATTTGCTGTGAGTGGG +ATGTCTGAGGATTACTGTGTCTCACCCCCCTTCGGGTCTGTTAGCAGCCTTGGTGGAAAA +TCTCTTCTGATCTGAGGAAATGTCATTTTAGAGTGCAGAATGAGAACACTTGATTATAAT +TTCTTGGGTTTCTAAGAATAAGTCTGAATAGCAAATTATTTTAATGGTTATCTTCCTTTT +TAAACAAATAAGAATTGTCTTAACGATTTAAAGAAAAAAGATAACATTGTTCTTTAAACC +CAAACGAAGCCCAGATGAAATTGTCATAGATCTGTTAATATCACAAAAAGACCTTTTCCT +AAATGACAGTATTTTGGAACCTGTTGGGAACCCCTTGATTTTGGAGCACAGTTATCTTGC +GGGAGCTTCAGGCCCCCACTGACTTGACTGCTATTCGGCTTTCTCAATGTACAGTGTAAG +GACAGACTACATTGTAACAACCCTGCCCCCTGCAAACGGCTCTTTTGGGGAAGATTCTGA +GGGCTGGGCCTGCAAATCTATCTCTTACTAAATGCCTCTGTGTATCACTAAAGCACTGCA +TGGTTTGAGGAGACAAATCAGGGAAGCCTCAGTGGTCACCAAGACCAACTTATCTGACAA +TGAACTCTTTGTCTCTCCTCTGCCCAGGTGCAAGTGTAATCTCCATGCCACTGTATGTGT +GTATGACAACAGCAAATTGACATGCGAATGTGAGCACAACACTACAGGTCCAGACTGTGG +GAAATGCAAGAAGAATTATCAGGGCCGACCTTGGAGTCCAGGCTCCTATCTCCCCATCCC +CAAAGGCACTGCAAATACCTGTGAGTAACTTTGCTTGGTAACAGCATATTCTGTGCACCA +TGAGGTGATAGTTCCTCTCAATTTTGCTTACAATTGTGATTTTATTCCTCTTACCAGTTG +TCTCATTCTTCTTTAAAGTGCAGCGAAAGTTTCAGTCCCTATCTTACCTCATGTAGACAT +CTTTTAGCACTCTGATCATCAGTAAAATTCAGTCATCTAACATTCACATCAAATGTGTTG +GGAAATGATACTTGACATCACAGAAGGAATTTTTTATAAGTGGATGAGACAGGAGGTGAT +TTTTTTCCTCCCCCAAATTAATTTCCTATTAAAATATCAAAGGCCTTGTAAACTCTCAAT +CCTAATTTAATTTTAGCCATAAACAATTTACAGAAATTATTTGAATGTTTACAGCCCCAT +TTCCCCTACTGAGTATCCTGAGAGATGCTTTGTCCAGAATATTTCTCCCCACTACAGTTT +TAGCTAGGACCTAACTTTGCCTTGTGAAAAGTTTGGCTGTTTCCAAACTCCAGCAATTGA +AACATACCTGCTTTGGATCCTGTGTGTAGAGGCCCCCTTTGGATAAAGAGCATGACTGTA +GGCCTGTGGGGACCACATTAAGAAAAAAGATTTTTCTACGCATGTGAAAGAGTGCAAGCA +TTATCCGCGTTTACAGAAACCATCTGTGTGCCCCCACTGAAATCCCTGATTCCCCATAGG +AAAACAGGCTCTGACATGCTCACAGAGAAATGTGATTATTTGCTGAATAATTTGCCCAAT +TCCATGGATGGACCAATTAACTACCTGCAACAGCCCAAGGTTTGCACTCTTTAAAAAGTA +GAGAAAGGGGGAGATTAGAATGTCCCCATTCAGTGAGAACTAACAGAAGCAGCCGGACAG +TGAGCACAGGAGAATCAGAACTTGAGAAGCCACTGCTTCCGTAGAAGGGTAAGAATGTTA +TCAGGCACTTCAAAGCAGCAGCTGTGAGAAACCAAACCTAAGAACTAGTATCATAGGAAC +CAGGACTTTATCAAGTTAAACGTAAGAGTAATGGACCAAGTAACAAACCATGAAGTATGG +GGGCATGAAATTATGATAACATTTCTATGAAGCAGAAAGAAATCCTTCAAAAGGTTTAAA +AAAATCCCTCTTTGTAAGGGTATTCAGTTGCTTTCAGTGTTAAAGAAAAAAAACTTGACT +TCTTGCTCCTAAAATTAATACATTAACGCTCTGTTGAGCAGAAACGTGGATGTTTCAAGG +TGATTTTATTGATGGAGACTCTGTGGCCTTTCCTCAATTGTTGAGGGCCACAGACTCATG +AATTTGAAAGGGATCTTGCAAGGTTATTTATTGCAATACCCTGTGGCTGGCTACCTAAGA +ACTCCTATGACCCCAGTTGTCAAATTTAGTTTAAAGCTTTCCTAAAGTAAAAATGGCTCA +GATTTCCTCTTTAATGTCTGCTCCTTCTTTAGTAGAAAAGGCTGGAAGAGTGTGATGTTC +ACAAACACTTCCTGGCATTCTGGCTTGTCCTCAGGGCAGGTCAGCTTGCCAAGACCACTG +GAGAGGCAGCAGGGGAAGGCTGCTGTTGAAGCCCTCAGCTTCTATTCTAACGTGACCTTG +TTCTTCTACCCGTAACTGTACTTTGAAGTTTTTATTTCAAGACATTTTCACTGGAAAGAC +TTTCTTGTTTCATCCAAGCTTTCGCATTGAAACTGATTTCTTGTTATTCTCTTGTTATAA +TCATCATGGAAATGTCTCCTACCCCGAATCCTTTGCATATTGAAGATCACCAAGTCACTT +TCTGACCAAAGGAATGAAACTTCTTTCAGTTTTCCTTGTAGGTCCAATTGTCCACCTATC +CCTTAGTTTTACTGGTTTTCTGTATACATTTTGGACGTTTTTCCTCATTGATGTTAAAAT +AGGCAGGTGATGGATGGACCCAGTGTCCAAAGGGGTTCAATTCAATATTCCAATCATCAG +CATGGCAGAAATTAGATGAAGGGTTTTAGAAACTATCTGCAGATCTGCAGTGGTCCAGTC +TTGCAATGGGAATAACCCCTTTGACTAAATCTCTGACACATCAGACTCTGCTTTAAAGCA +TCTGAGGATGGAAGTAAGCAGTTTAGTAGTTTAGTGCACAGACTCCAGGCTGGAATCCCA +GTTTCTCCATTTACTAGCTATGTGACCTTGAAAAAGTAAGCTAACCTCTCCAACACTGTT +TCCCATCTCTAATGCGAGGATAATAACAGTTATTACCTCCTGTGGATTTTTAGATGGTTG +ACTAAGCTAACGCATGTCATATGTTTAGCCTAACACCTGTCACAAAATAAGCATTCAAAA +AATAATTTATTTTTAGTTTTTTTCATAAGACAGTCTTGTCCATTGTTGGACAGTTTTAAC +TGGTATAAAAGTTACTTCTTATCAAACCTTTTTTTTTTTTCTTTTTAAGTAGTAAAGGAA +GTATATCGACCCTGGCTTTATTTCTTCCCCAGATTAACCATTATCGACTCCAATTCTTAT +GTGCTAATGTTTTCATGTCCTTTACCTGGTTGCCTGCTCTGGAAGTCCTCTAATTCATTA +GTGTAGTACTTCCAGCCAAGCACAGGACCTTCAGCAGTTTTATGATTCTCACTTCATATT +GGCTTTTTCTTACACATATGCATACAGGTACACACACACACACACTCACATGACTCTAGT +GGGTACGTTACAAGTCAGTTATCTATGAGGGATACTTAGGATATATCATCCCCTAACATA +ACACAAAAGCTACAACTTCTGGTCCCTCAAAATCAACTTTTCAGGGACCTAGAAATGCCA +CTCATCCTGGATAATCTCTAGATTTAGCAGAATATCAAGTAGCCAGGATATTTTTCAAAT +AGGATGACGAGTTAGTGGGTGCAGTGCACCAGCATGGCACATGTATACATATGTAACTAA +CCTGCACAATGTGCACATGTACCCTAAAACTTAAAGTATAATAAAAAAAAATAGGATGGT +CAGTTTCTGTTCACCTTCACAAGTTTTAACAGAACAACTGGGAGGTCTTAAATTAAGTCA +GGGAATGACAATATTCTTCCCCAAGACACTCAGCCCACCACTCAGGGATACCATAGATGG +GAACTTGCTGGGAGTCATTTGGCTTTGGAGGTCCTCTATTCTGGAGCAGTTCAAGACCAC +TGTTGTATGAAACATGTAGAGCTAAGCAGAAGTGTCAGAAGGCCAACATTCTAAAATATA +GCCACCCCAGTCTGTGAGACACACCACATTTCCCTATGCTTTTCATGACAATAAACTTGA +CAGAGGCAGAGTAACTTTTGTGATATTTTTATTCATCATGCTTTTATTCAAGACCCAGTG +TGTTTTCTTGGACTTTTAAAGCCATGCACATGTATATCAAAATCTTTTCTTTCTTTTTCT +ACAAAGCTTATGTTTTATAGAAAAGACATTTTTCTTCTCCTTATTGATCTTCATTCTTTT +TTGATAGAATTCTATTTTGGATGTCCTTTGAATTTTATTTCTGTCTTCCAAGTAATAGCA +ATTCTGTCCAACTTCATGCTTAATTATGATTCTCTTGATTCCCCATTGTCCAGCTCATGA +ATAAAAGTATTAAATAACTCTTTAAACTCTGATCCCTATGGAATAACACATGTTTTTCTA +TATATAGATGCTAAAAGCTTAATAATCACTATGTAGGAATCCTAACTTCAGCAAATATAA +TATTATACCTATACCTCTCCTTCTCTGGCTATGTTCTATGACCCATAAAAGCACTCCATG +GCCAGCTAAGTCTGAAAAATGCTGTATACTATAGACTATTCATATTACATTACTATAATA +GAAACATTTGAAAAGTCCTACAATAAAACAACCTATTTTACCCAATGTTTCTCAAACTTA +TTTGCTCCATGGACCATTCAATAACTTTCTATAAAACACTCTTATGGGGACATGCTGAGC +TAAACAGTTTCTTGCAGCCTAGCCATAGAAATGTCATGGAGATAGACAGAAAACTGAGCA +AGTTCAGCTGTATTCAATCTTTTCCTTTTCTCTTACCCACATGGTCTAATTGTCTTCAAA +GAAAGAAAATCAAATTGGTCTGACTTTGACATTATTTGTTCATAAATCTAACTTGAATTG +TTACACAATATCTAGGGGTCCTCTGAGTGATGGAAAGTAATTTGATGATTGTTCTATTAT +TTTCTCTGGTATCAAGTTTGCATTGACCAATTTATATTTTCCCAGGTGTACACATGTATG +TGTCCTTATCCAGACAATTTCCTAAGTGCTTTATATACATTAGTCCATTCTAAACTCAAA +ATAGTCTTACAAGGCAAATACTACTATTTTAATTTTAAACACATGGAATATTGTGATTTC +AGAGGAAAAAGATCTGTTTAAGGTTTGCACAGCTAGAAAGGGTTAAAGGGAGGATTTGAA +TCCAGGTGGGTCTTGACTCTGAGGACTGCACATTGCACTGTATTGCTGATCAAGTTAAAT +TTGGATGACTTTCTCTGTCCTCCACTGGGATTTAGGCTCCATTTCAATGCCTATTTGAAC +AAGTCAGTTTTCTCTAAACCTGCCCTCTTCCTTCATCTCTGCCTGTTATTTTTCTGCCTT +CAAAGATTCCCCTTCTATTAGTCTTTTAAATCTCCATGTTCCCCACCCCGGCTGTTCTCA +GTCTACAATTTTTTCTTGACATTCTAGCCTATTCTTGTGGTTTTAGATCTTAGTATTATT +GATTTAGTCGTAATCAACCAATTCTAACTTCAATCTTTCTAATAAATTCAGAAAAATTTT +TCAGCTGTCAGTAAAGATCTCAAAGTCAATATGCTAGATACTAAATTCATTTCTTTCCCC +TAAAGCATTTTTCTCTTCACTCTATATTGAAATTCTGCTCATTTTTCAAGACTGCTCCTC +AATGCCTCATTGAAGCCTACCTAGACTCTCCTATGCAAAATCAATTACTTCTGTCTCTCT +CTCAAATATTGATAATGTGTGTAGATTTACAACTGGTCAACTATCTTTAGCCAAAATTAT +TATAATAATGATAGCTACCATTTATTAAATTTACTACAGGCTTTTACACTTCATAAAGTA +CTTTATGCTCTTTATTGGTTTAAATCCCCACAATATCCCCATGAGATATGTACTATTATT +ATCCTCATTTCACAGATAAGGAAATGCAGACACAGAAAGGTTAAGTTGTTCCAAAGTCCC +ATAGCTAATGTATGACAGAGCAAGATTTAAACTTAGGTCTGTCTCATTATAGGAACTAAA +ATGTGAGAAATTTAAGAATAGGTCCATGTTTTATTCTTGGTCTTCATCAACGTTTGTGGA +ATAAGTTTTTTTTTTTTTTGAGATGTAGTTTTGCTCTTGTTGCCCAGGCTGGAGTGCAAT +GGCATGATCTTGGCTCACTGCAACCTCTGCCTCCCGGGTTCAAGTGATTCTCCCACCTTA +GCCTCCCAAGTAGCTGGGATTACAGGTGCCCACCACCACACCCAGCTAATTTTTTGTATT +TTTAGTAGAGAAAGGGTTTCACCATGTTGGTCAGGCTGCTCTCGAACTTCTGACCTCAGG +TGATCCACCTGCCTCAGCTTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACCACGCCCA +GCCCATTTGTGGAATTACTTTTGTGAGTGGATAAGTAAACCTAATAGCCCTGTAATGTGC +ACGTGGCTACACTGGCTTCCCATTGATATTCTTGTATCTCCTGGAATATGTGGCCTTCAC +AGGTCACCAGCTCCAACACAAGAGCCTTCAATCTCCTACAGGAGAGACCATCTGAGTTCT +TGGAGGAACTTTAATGGGAAAAAGTCTCACTGGTGCTCATGGCCAATCGAACCATCTAGA +TAGCATATCGGATGGCGGATTTTCACAGGCCTCCCCGAGGGTTATTTACTGCCTGGGTGG +CTTGACTACCAGCCTTTCTGGCTCAGAATCCTAATTTTGTCAGCGCAGTAAGAGAGGTTC +TTCCACATATGTGTATGACCAAGCTGTAGGCCCAGTGTTGAAAACCGGAATACCAAGTTA +TTCAGGTACAACCACTGATCTATTGTCTGTGGTCCCTCATCTGACCAGATATGATTTGGA +ATTCAACATCTTTAGGATTTTACAAAGGTAATACAGTGCACATATATTACAACAATACCC +ACAGCAGAATATTAGGCAACACCATTTAATCAAACATTTTAATGTTTCTACAGCAAACAT +GATTATTCTCAGCAACTGGGATGAAGTAAGACTATAAATAATACCCTCACACAAGTTTCA +GTACAGTTTTGCCACCAAGTTAATTCAGATCACAGTAGGTCATATTGCAGGTACATGTTG +AAAAAAATTTTAATTTTCATAGTTTTTTTTTTTTTTAATTTGAGGGCTGAATAATAAAGT +TCAGGGCCTGAAATAAATGGAAAGACAGTATAGAACGGTGGCGATGGGCCTGAATTCTGG +TACCTGGACTCTGGGCTCCAGTTTCCTTCCCAACAGACTGAGATGATCTTGGGCAAGTTA +CTCAGCTTCTATGTGTTTGAGTTTCCTCCATCTGTAAAATCAGCCTGATTATTGACGTCA +TAGGATGGTCATAAAAATTAAATGAATTAGTACATGTAAGGCATTTAGACAGTGCCAGCC +ACGTAGTAAGCAGCAGTGCAATTACCTGCTACAGTCATTATCTTTTCCCTGAGACCCAGC +ACATAAGCAGCAAATTCTCCCCTTGGAGACAGCAGCTATGTAGGGAGATATATTGTGGCC +AACTGCCTGTCTATTCAACCACAATATGAAATAACTGTCATGGTGTTCAGATTATTCAAG +TCCTTATGGCCAGTGTATTATCTTTCCTGTAATTAAGTCTATGTGCAGAGCCAGATAATA +ATCAGGAGGTTGCTTGGTGAGCATGGGATCAGGAAATTTGAATGACTTGAATGTTAATAA +CATCGGGCTGAAACATCCTGACCCATCCATCCTGCCTCAGGGTCAGCCTTCTTCATGCCA +ACAGGACACTGAAGGTCTGAAAGTTTGCGGGTTACCACTCCCGCTCTTGAGACCATGCTA +GGACGGTACTGTCACCATATGTGTCAGGATGCTCCTTTTGTGAGGCTTCCACCTTCTGAT +TAGCTAGTTCTTCCACTCTTCAGATATGCTAACATGGTAAGTCAGGTTAATGTCACCTCT +GTTGAGTCTGCCACACACACTCAGGCCCCAAGCTCTGCTACTGCTATAAGATGACTGTAG +CCATTTCTGCTTGGATCATTTATATGATGATTTCACAGCATACATCTTTGAAGGTGATCT +TATTTCCCTCACTTTCAAGTTTCTGGGAGACAACTCACTGCATCTCCTATCAACAGCAGT +TTATACTAGGGGCCAGGACTGGAAGAACATTGGAAGTAATTCCTCTGCAATACAAATGAA +TCTGCAGAATGTTTTCTTACTCATTATCTGCGTTTTCTTCAACTTGAAGAAGTTTTTTTG +GAGTTAGAATTCCTGATGGCTGCAGTCTGGCTATAAGATCTAGTTACCCACTTGATGGGT +TTTTCAAACCATCTATCACAACAGTGGTAATTTTTCCTCTCAATTTGAAGCATGCCAAAT +CCTTATCCCTTCTGCTTCCTTCCTGATGAAAAGCCGCTGAATCTTCCATTGATTCTCAAA +AGGAGTTATGGCACTGTATTAATCAGCTTCTGAAGAGGAGGGTATTTATTTTTGAAATCA +TCATTTTGACTTCCTTAAGCATAACAGTGTACCCTTAAGTTATTTACTTGGTTGGGGGAG +TAGTAAACTTATTTAAAAAGAAGAAAACATCACATTATTATATTGTGTAATTCTACTAGG +TTCTCACCCCCCTAATTGCAGCAGAATATCTTTAAAACAAACGTAAGTGGGAGAAGGAAG +GGCTGATTGAGGAAAGAATAATTGCAAGTACCTGCAAGACAAGTGCTTTCTCATTTTTTC +AGCGTATGGTAGCATAATAGCCCTTTAGCTTACTCAACACGTATGTATTTCTGTGGTTGA +AGTGACATTTCTGTTCTAGAAGAAGCGTTATTATTAAAATAGTACTAATTGCAGAAACTT +CTGTTAAAACTCATGCACTGGGGCTGAGCGTGGTGGCTTATACCTGTAATCCCAGCACTT +TGGGAGGATGAGGCAGGTGGATCACCTGAGGTCAGGAGTTCAGGACCAGCGTGGCCAGTA +CGGCAAAACCCCATCTCTACTAAAAATACAAAAATTAGCCAGACGTGTTGGCATGTGCCT +GTAATCCTAGCTACTCGGGAGGCTGAGGCAGGAGAATCGCTTGAACCTGGGAGGTGGAGG +TTGCAGTGAGCCAAGATCAAGCCACTGCACTTCAGCCTGGATGACAAGACTCTGTCAAAA +AAAAAAAAAAAACCTCATGCACACCTGTGCTTCATTTCCTCTGCACAAATTTAACAATGC +CTCACACAGGGACTAGAAGTTACATGCTCTGATGTTGACTATAAAGGGATGGACTTGGAC +AAGGCACTTGAGTCTCTTTGTGCCTCTTCTATAAAATGAAAGGGCTGAAGAAGATGATGT +CTTAAATCCCTTTCAGCTTTCATTTGTTATCACTCTTTCTGAATTAACTTATCTAGTATC +TTTCCTTCCTTCCGTTCTTTTTAATTTACCTGTCATCTCTTTATCTTTCCCAAGTATTTT +TGAGGTTGTTCCAGAGATGGAGTTAAGCTAATGAAGCTTAAACTTCAGGATCCCTCACTG +AACTCCTTCTTAATTTATATATATATATATATATGTATAATTTTATATTTTAATGTTAAG +TTGTTTTTCTTAAAGAGAAGTCACAGAATTGTACACATTTTATGTCCCACAAAGTCTGCA +CTTGCCCCTGGGTGTGTTAGGAAAAAAGACAAATACAAATGAGAGTATCAAAAAATAGAA +TTTAAACAGAAGATCCGAGAAAAAGAATAGAAAGAAAATAGGCCAAACATTAAATGCTAA +ACAGTTTCCCCAGCTGAGCATCAAACTGAGCTCTGAGTTTCATGGAAGGCAAAGTGGTAA +AAGGAATTTGTACATTGCCTAACTCTTGTTATAAGAATGTTGCATGTGTTCAAAGACAAT +ATGTATTGTTAATATTAACAATTAATATCCATTAATCCTGAACTCTGAGAAATCTCAGTG +GAACACTTTATAGGGGATAAAATCACCCTTTGACCAAAAAGTGATGTTTTCACAATGATA +GTAAGTTTCATGGAAATAAGTAATAAATTTTCTGATCCAATATACATTGAGCAACTCTTA +TGTCATCAGACATTGTCCCAGGCAGATCCAACAGGTGCAGAAGGGAACAAGACATGGAAC +TTGTGCCCTCAGATCTGTCAGGCAAACACATTAAAAAAATGCAAAAACAAGTTGATAAAT +TGATCATGGAGGCCTGTACAAAATGCTATGGGATCACAAAGGAGAGAGTAGCTAACTCAC +ATCAGGGATGTGGAGGAGGAAGGAAATAAATAACTTCTGAGCTCAGTTTCAAAGGTAATA +ATATTCTTTACATGGTAGTTGTCAATTCACAGAGAATGCTAAAAAACTGCCAACATGTGC +CTAGACAGTTTTCCTAAGCACAGTCTGACTCTCATTCCTGTGGCTTTTAGACATAGTCAC +TGTTTGTTGTAAGATGGAATTGCATTCATTGATTCATTCCTCACAAACCCCAAAGATACC +CCAGCTTTCATGAAATAAATTGTTGCACTTCATTTCTAGCCCTTTCCGTCTTATCCCCTC +AAGTGTTTGAGGAATTTCTCCTGGCTTACCTGTAGCCTTTCTAGTGGATTTATGAGTTTA +TTCAATTCTTTATCTGTGGAGAACCACAAACAAGGTATTTGGACATTAAAATAAGAAGCA +TTAGAAAAAAATAATGATATTTTAAAATATAGTAGTGGACATCCCTTGGTGTTCAGATAT +TTTCAACTTCAAAGGTCTTTATTCAAATGAGCAGTTTAAAAATCTTTTCTAAGCAATTCC +CATTTTACAGCAGAGGAATAGAAAAAATGACTCATCTGGCAGCACCTCAAAAAATTGTAA +GCCACAAAATGAGGAACAGCCTGAATTTTAAGCAACCAATGTTAGGTAATAGAAAACATC +TTAGTGAGAAAAACAGAATCTCCTAATAGCCTCGCTTGGTGAGGTTTGGAAACTTGGAAC +AAACATTGCTCCCCTGCCCTGGTACTAAAGGAATGAAAAAATTTCTGCATCTTTCCAAAG +TATTCAGCTGCAGCAAATACTGCATCAAACAGTCTTGCGGCTTTGTTTTTCATTGTATGG +TGCCAAACACCCTGAGATCTCTGCCTTGCATAATGCCTGGCCTTCTAGCACCTTGTAAGT +TTGTAAAGACATGAAAAGTCTCTTCCTGCCATCCCAACTTCCATTCTCTTTGATGGATTA +CAACAGGCAAGCAGTGCGTTGCAATGGAGCAGGATTTTCAATCATGGAAAAATTTGGAAC +TTCTGCAATTGATACTAAAATTATGATGCTGCCATCATATCTCACTCAACAGAGGATTTG +CAAAAAAAAATAAAGATTCAGTATCAAGTCACTGTCACACTGCAGCAGAGGTAGTCTACT +GAAGTGTCAGGTCAGGAATTCAGCAGTCCTTTGCAGAAATCACGTTCAGCTTGAAATTCA +TAGGGTAGAGTTAAAACATGGACATGGAAATTTGGATTTCTAGTTTTGGTTGATCAGTAA +TTAAGCTGAAGCACTACAAATTCTGAGCATTTAAAATCAAGATATTTTTTGTGTTTCTAA +TAACTAAAATTAAGACTTCATTCTTTCCAGGGTTTAAAAGAATCAGAGTAAGTCTTAATT +TCTTATTCTCTCCTACCCACTAAAAAATAGGAAAATAGTTTTAGGTTTTAAAGAATACAA +AGCTAGAAATCTCCGAGCAAGCTAAAATGATTAGTTAAAATAAAACAAGGGCTGTTGTTC +AAAGATAAATACTAAAATAGAACCTTAATGATTTTCACAGTTACCACCTGTTACTATACT +TCAATGATGTGAAGAACAAGTCTGAACAACTCATTAACAGCTACCGTTTATTGGCCGCAC +ACCATGTGTCAGACATTTTTATGGATTATCTCATTCGATCCTCACGGCAGCCCTATGCAG +TAGATCTTATTAGCCCTTTTTCAGATGAGGAAACAGTGCAAAGAAGCTAGCAGACTTGCC +TAAAATCACCCAGCAAGGCGGTATAAAGCAGAATTCTCACTGAGTTCTGTCTGCTTTCCA +TCGCATGCTCTCCTACCCAAATTAGTGGTGAAGATGTAAATCTCTGGCTTTTAATTAACA +GCATCTATCATAATGTTGCTTGGTGAATGAGCTATAACAATAATAGTAATCATCGCAAAG +ATGGACCTAGTACATACTACCTGTCAAGCAATACTCTGAGTGATTTACATCTATCAGTTT +ATATAACTCTTGCAGCAACCCTAAGAGGTAAAAAACTGAGCTACAGAGGGCATAAGCAAC +TTGCCCCAAAGTCATGTGGTCAGTGAAAATTTAGGAGTTGGAGTCAAGCATCAGACTCAG +AGAGCCTGGCTTCTGAGCCCAGACTATTGGCCACAGCACTATATTGCTGGGTTAGATACA +GACTAAATTCATGTCCACATTTATACCAAGTCCAGCCATATTCTGAAATGGCTTCTCTAC +CTTAGCACAACTTGTGAATTAAAGTGAAAGCTGAAAAATCGATGAAGTCCGTGATCAATA +TGCACAACCTAATGTATTCTTGAATTATTCTGCTCAATTGAGTTTCTATTACAGAGTTTA +ATCCACACATCTGACAAGTAAAAGAATAAAAATGATGGTTATATGAAATTAATCAAATAA +AATGCCACGTGATTTTCAACAGCTAACACATGCATCTCATAACACATTTTAAAAGGTCTA +TTGCATATGTGAATATATTTGCACGTGTCCATAGAGTGTATATTTGGTACTCTGTACCCA +TAACTTAAGCCTGGTTTAATATCTAGTTTGAACCACCTACAAATGTTCATTAACCTTATA +GGGAAACACAAAATGTTGGATGTCAAAAGCTTACTTGGACCAGATGCCGAAATGAGTATT +AACTTCCCAACTCTGATGAGCCCAGGAGTTCTAGAATGAAACAAAATGGTTTCAATTGCT +GGAAATTGTGTGTGTGTGTGTGTGTATAATGTGTATATGCATATATATGTGCACCTGTAT +TTTGTGTGTGTGCTAATTTCTTAATAGTCTGAATATTATCAAGTGTCAAGTTTCTAAGAT +TTTTATATTAAGTTAAAGATGTTATGTACTAATAAATAGCTAACAGCTTTTCTTTATTGT +TTTCTTTTTCTCCAGGTATCCCCAGTATTTCCAGTATTGGTAGTAAGTAAAAACAAAAAC +AAAAAAAACACCAAACCAAGTCTAGGCTAGCTTTGCTTTGTTGTTCACCTCCTCAGATCT +ATTTTCCCAGTGTCCATTTCTGATGTAATAGGGTATTTTCTTTGTGAATTGCATTTTTGT +GTTGGTTTTCTGCACAGATCTGGTGAGAACACAGATAAAGTGATTATTTGTGCATAACTC +CATGAACATGGCAGTGCTATGACTTTTCTGACTACTCTTAACCAGTGAGGGCTACCTAGA +CTCAGGTGCAATTCCTTAGATAATCATCATTCAGGAAAAATATAAGTAGTCCTATTTATC +CATACTTAGCAACCAACAAACAAATTGAACTCTCTCTTAGACTGGATTTGGATGTCTGAC +ATAATTTTAAAAAGCAGAAAATGAAAGCCAATGAATGCCTTGGGTATATGCATCAGAACC +CAAGAAAAAGTCCATGATACCAAGGGAAGGGAATTTTGTTAATGCATTAAATTCTATGTT +TTGTGAAGGCCTGAAACAGGCAAATTTGTGATCAGTAGTCTCTCTGGAGAGATAAAGGAA +AAAGAGAATCTGTACATTCATTTCTCCTTCCTAAAATACGATGATCTATGTCTTCTTGAC +TACTTAGCTTTGAGTTTGATATAGAAAGAGTATAAAAAATATGTGCAGAATTTGGGAGTG +AGAGTACTAGAAATTCCTTTAATAAATCTGTTAGTATGAATCCAAGCAATTGAAGAGAAA +CCGCTCTTCAACCATCTGTAGAACACTTCCCCAGTATCACTACAAAGAACTTTCTTCCAG +CTATCATGGGAGAACCAGGTGTAGCTCCCGCTTCATGTGTAAAATAATGATGCCCTCATG +CCAAGCCTGAAATTCACATTAAGAAAATGCCCAGTAACTTTACAGAGCAAAATTTTAAAT +TTTTTTTTATACATTGCACCCTTTATCTCTAATGGCTAAAATCTTTGAACAACTACTAAG +TAACTGATTACAAATAAATTACCGAGAAAGCAAGATTACGCATGGTAAGCGGAGAGAATT +TTCACTGTAGTGTCATCCCCTCACAGGCTTGTGTCATAGGTGCTGTGCCAGGCAGGGTGA +TCGCAGTGTAAATAGCCATTGAATGATTGCGATTCCCAGCATCCATCTAAAAAGCAATAC +TCTGATAATTTGGATAAAGCAACTTCCTGCTTCTTATAAATGCACAGTCAGGTGTCCCAA +TTTATAAATCAACCCAGTTTACTTGAGCTTGTGAATAGGCCTGGACACTGATTTGTTAAG +CGCTAGATGTGGTAAATGCCATGAAAATTGGCCACTTTGTAAATAGAAGTAGTGTTCACA +TCCATTTAGAGATACCAGCCTAATGCTACAGCATCCTCTTTGTGATCTTGTTGAAACAGC +ATCAGTGTTAAAAACTTGCAAATGAAAACCTTCAGCTCTAATAGTCTAATTTTTCTGCTT +TAGTATCCCCCTTGGCATTTGCCTAACTGTATATATACCCCACAATGTGCTCCTTTCAGG +CCTTGACAATTGCATTTGCACGTGCATTTTAGTGCAACAGGGAAGCAAGTAGAAGCAAGC +TGACACAGATTATTGAGGCTGCTATAGTGATCTGGCCTGTCAGAAGTTTCAGAAATGGAT +GGATGGAAAAGTAGTTCTTTGGCGTTGGGGTGTCTTTCTGTTTGGAGTGTCAGTTGTATG +TTGCATGGCCCCTCTAACTGTACTGCTCACTCGACATCCCATTCGGCCGCCTCCACCACA +TTCCCCATATCTGAGCATCAGCAGATGTTGACCTTTTACACATCAAATCAGGAAATTTCT +GTTTTGTTTTGTTTTGTTTTGTTTTGAAATCAGTGGTGACCTGAAAGGATGCTTCGTTGT +GCCTTTGAAAAAAATATATTAACCTTTATTATCGAGAACCTAGGAAAATTTACTCCTAAT +AAAAACCCTCTGACTAAAAGTGATATTTTGGACTCTCCCTTCAATATGCCTCTGGCTGTT +CCGCTTAGAATGCAATGGGTATTTTCTCAGATTTCCAGCAAACAGGATGTAAGAGCTTCC +AGAGGTCACCCAACATCACACATGACTAGCTTACCTGTTTCCTGGCTTTTAAGGTAAAGA +GTTACAGTAAAACCATCAAACGTGATTGTATCTTCTAGGCTGCTTTAATGGCATTCGAAA +GTTCCTTCTTTGTGGGCTTATAAGTTGCTTTTTGCGTGCACTCGTGGATTCCTTTCCCCT +CCAAAGGGCAAGAATTCACACGTAGACGACACTGCCTGTTCCAGAGGGCACGGGAATGGG +GTTTTCAAGGTGCAAGCCAGAGAAAAGGAAGCTGTTTGGATATTTAGCTAAGTTATGGGT +GTTTGCCAGTGCTTTTTGCATTACCCCAAAGAAGGAATCAATGACTATAATTCCACTAAC +TATATAGAAAGATACCATTATAGCAGATGTAACACCCCTGAGACCCCGATTATCACAGCA +TAGCTCAAGGAAAATAAATGATGTATATTATCGATGTAGATTATTGATGTATATAACCAT +CAGTTTACATACATATTCTGTATACACAGTGATTAAAGGTTTTGGGGCCCTAATAAATTT +CAGTATAGATCTCAAAATGCCAACGCCTGTATTAAGGTTCAAATGCATGGATAGGGTGGT +CATCCTTTCCGATCATCTGCTAAAAATGTTTTTGAAACAAATTTCCCATTAAGGTCATTC +GTACCTGCTGTTGTCTATCTATTAACAAATAGGTTTCCCATAATCCTAAGGATACTTGAC +TTAGAACTCAGTCATTCTGATCTGCTTTGGCCATGGCTGAAAAAATGCTGGTGATATTGT +CAGCAATTAATGAATCCCAAAATAAATCTGTAGCCTTTGAGCCTTATGATCTATGTTTTC +ACTTTACCTGATGTGGTAGGAATTCCTTCAGATTGCATTTTTTAATAAAGTGTATTATGC +ACTTATAAGTAAAATTCGTGATTTTATCCAAGTGAATATTTGTTGCTGCCGATAATCCAA +AGTAATAGTTGTCTTGGTGTGGGTGTTTTTGTTCAAGTGATAAACTGATCATTACCTTCT +AATATATATCATATGATCTTTGGTCCTGAAAAGCAAATGATTACACAAATTATGTTAAAC +ATTATATTATAAAAAGCATAATTAGACCAGCAAGAATTGGCCTAATGTGCAAATACATTT +GTGTGGGTGATCATCACTTCTTACAAAACTGAATGACAGATGAGTCAGAGGTTAAAGTTA +AGCTATCCACAAAACAAAGATCACATCAAGGAAGACCATTTCGAACTCTTGGAGTTTTGA +AATAAATAGAATTTTTTAAATAACACAAACAAAAGAAGAGAGATGTACACATTTTGTGAA +CCTGACTCTAGAGTATTTCCTTAAATTACTTTCAAATGACTGGCATGATGTTATATGAAG +CATAGAATACTGAGGAAGGTGTTTGGCTATTCCTCTCCTGTCCCCCACCCTAACTTATTC +AATTTAAAACAACAGTTCACTTAAGGGAAATAGCTAATTGTCCTGTTTTATCTTATAGTA +AGCAGTGTCTTCATCACAGAGTTAAAAATTCATCTCTAATTTGATGTAATTGGCAAGACC +ATTAAACAAGGGAAGTGCTACCTGCAGGGATCTGTCAGCCTGTTGAGGAAGCCCAGAGAT +GTTTTCATACTTGAAAACATTTTATGCCAGTTGGAGACCTGGTAAAAGTTGTTTTCCATA +CAGCATCCAAATATTTTTGTGCAGTCTTGATTTATTGTAGAAACCTGGATAGTCAAGAAA +ATAACAAGGTTAATCATTTTCCCACCCAAGAGTTATTAATAATCGCATTCATGTTATACA +GAGAGCTGCAGTGTTTGTTTGGGTTTTTTTTTCCCCTTTGCTTTAATACTTCTAAATCCC +CCAAATAAAAGTTTCATTTGAATTGCCCTTTAACTAATTAGGTTTTATGTAATGAGGAAA +AAATTATCAGGCTAGTGTAGCGATAGGCAAATTGCATGGTGTGCTACATTAATTTTGAAC +TGTTTGCTGATGTTCTAGAAGGAAAGCTAAGGTCCCAGGTGAAATGCCTTTGGGACTATC +ATGTACCCAGTATCCTCATCACAGAACCATTTCATATTTGTGTAAATGGCATTTCACATT +CATGAAATCTTGTGGTTATCCTAAAATTGAATGAACATTAGGATATAGCTGCCTCTTTAA +TCCTGAAGAACAAATCGAATATTCCAATGGAGGAGCTGAAATAATCTCCTACTTAAATGT +CTTTTTAAAATCCAATAAGTTTGCCAATCTTTATTGACAACAATTGCCCACCTTGAGCAA +ATTAACTTTATCATGTATTAGCATTTTCCCAGGTGACTTTACAATGTCAAGCCACTTTTT +TTTTTTAAGTGTGAGCTGATATCTCTGCCTTTGCCAGTTATCTCTGTGGGGTCAGGAAAT +TCGTAGCTTAAGCAAAAACTTGCCAAGATCTCCAAAAGGTTTCATTTGATGAGACTTTAG +ACATGTTAACTATGAATTCCTGTACTGTGCCAGTTACTTCAAGGATGTGGCTATCAATTG +AAGTCTTCTTGGACTATCAATGGAGAGCTGTCCAACTAACCATGCCACTGCCTAGGAAAA +GTTATTGTAGGGAGGTATTCCCACATGTCTACAGAATTCTGTTTTACAAATGGTGAATCT +GAGGTTTAGAGTGGCCACATAACTTGCCCAATGCAGTACAACCAGGAATGCCTATCTGGC +TGCAAAGGCTACACTCATAACATTATACCAAGTGGAAGAGATTAGAAAAGAAAAATTGTA +GATTAATTGCCTCCTACCCTAGATTTTTTCCAATCCATTACACTGTGCCTTAGAAGACCT +GTTGATCCCTAATTGACCCATTTCTATGCAGGGAACTGTAGAGTCCTGGAGAAAAATCAG +AGTTCATTTTCGGATTCCTTATTGTGTTGTCACCTGGAGAACTTACAAGCATGGTGTCTG +AGGACAGGGATGGAGGACTGTGACCTCCCCCTTTCAAAATATACTATTCCTCTACCACCA +AACATCTTCAATATATTGAGGAAGAGGGAAAATGTATAGATGTCAGGTATTTTATAGAAC +ATGGAACAGTTTGTGAAATTAGCTATGCAAATTGTGAAGCATGCTTATGCCTACTCTGCG +ACAGTAAACCAAAAATTTTTCTTCATCAGGATAGTTGCTTATAACAAAATAAAATTCGAT +ATGCCATCTCAAGGATAACTCTGCCAGTATCACACTAAACTCTGTTTTCCCCATCTGTTT +AATGATGGTGTGTTTCTGATAGTAGGTAGTTGCTGCGAAGATGGTAAGATTACCTCCAAG +GCTCTGGGGATTTCTCCTGTAGAACTTTGGAGTTTCCTGTGGATTTCTTTTCTTTTCTTT +TCTTTTCTGTTTTTTGTTTTGTTTTGTTCATTTTTTTTTTCATTTTTTTTTTCTGAGATG +GAGTCTCACTCTGTCACCCAGGCTGGAGTGCAGTGACGCAGTCTCAGCTTACTGCAAGCT +CCACCTCCTGGGTTCACGCCATTCTCCCACCTCAGCCTCCTGAATAGCTGGGACTACAGG +CTCCTGCCACCACACACGGCTAATTTTGTTTTTGGATTTTTAGTAGAGACGGGGTCTCAC +CCTATTAGCCAGGATGGTCCTGTGGATTTCTTTCTGGGCATCAATAATGCTATTTCCATC +CCAAGTGCGGTGTGTGCTTAAAAAATTTTTTTCAATTAAAAAAAATGCTATTTCCAGATT +TCCTGAGGAATGACAGCAGTGACTGTATAAACCCAAAGGGACCTTGTAATTTTATCTCCA +CCAGATAGTTTCCTCATATGCCAGGGAAGAAGAATGTTTAAGTAAGGTTCACTAACATCC +TCACAGCAGTGGCACATCATATCATCGTGGTATCCTGTTTCTCACAGGTTGCCATATTTT +AGAACCAAAAATTATGTAAGCATTAGTGTTGTTAGGAAACTTAATAAAAAAGCAACTCAT +CCACCTCATCATTTTCCGACCAGGCAGCCAAGTCTTAAATGAATTCCCTAAAGCATCTAA +ATAATGACAGAGCCAGAATTCCAGCTCAATGTCCAATTTCCAAACCAGGACTTTTTTCAT +TCTACCATGACATTAGAATTGACCTTCTCATTTATATAAATTAAACTAAAATATGAGATA +TTACATGGTAAACAATAATAGAAAAAAAATCAGAAAACTTTTTCCTTGATGGGAAAGTTA +CATTTTACAATGTTCTTAAAGGCCATCCACAAAATGACTTGAAAGCTGCTCAGTAAATGC +CATGTGTGATAGAAGACAACTTAATATTCTAAAGCAACTCTACCTCTAAAGCTTTCTTGA +TGTTAATAAACTGTCTTTAGTTTTCTGTTTCAAGCTTGCTTTGCAGCTTGACTCACTGGG +ACGTCAGCACTAGACAGTCAGGTTTAGCAATTCTATCATAGTTTTCTTCAACTTACAATG +CAGTGAGCTTTCCTTGGGTGCAGAAGAGCAAAATATTTCCTTCCAGAGTCCAATTTTTAT +AACCAAAATCTCCATTTTTCTCATTCATGAAAATTGATTTCAAGTGCGACCACTAAATTG +TCATGTAACAGTTTGGGGGTGGGTTCTTAAAAAAATTGGAGAAACTACCTATTTGATTCA +TATTCTAAGCTGATGTGGTTCTAAACCAAAAGAAATTTAGGAATTACCATTTTCAGATTA +AAGGTTAGAAATCAAATATTGTCCACAGTATTACAAAATAATTTGTATTGCTTTCTGAAT +AATAGTAATTGATAGAGGCCCTAGAATTGGATTATTCTCTAAATTAAGCTATATCTTAAG +AGATCTTTTTAACTTATCAGATCACTTGGGTTAAGAACAATTAATACTGAAAAAAATAGG +GGAAGACATTATTTTCCTACTTCGAGTCAGTAACTGTTTATAGTACAGCAATCTGATTTT +TATTTACAACAGCAACCGCAAATAGAATGAGCTAACATTTACTGAATGCTCACTATGATG +CCAAGCAAATATTAACTCATTCTGTCTTGACAACAATGAGTAGCAGACAGTGTCATTATC +TATTCCATTTTGCAGATGAGAAAAGCTAGGCACAAAGCAGTTAAGGAATTGTTCAAGTGG +TGGAACCGGACTTTTAACCCAGCCTGAGCTCTATTTACATGCACCATATCTTAAATAAAT +TTATCCTAAATAGATTATTTTCTAGGCTTCCCACAGATACAATCTGAAAATTCAGACTAA +TAATAGCAACTGAAAGGCATTTCAGATATTTTATTTTTTAAAGGAGGCAGTTGTGGAATA +AATGATTTTGGTCTCCATACTACATATGTAGACATAGTCTTTGGAGCCTGATCAGGGAGA +TCCTCAAGACAAATTCAGTCAATTTTAACAAAGGTATGGAACCAGCATCCTTAAGAAGAA +GTGATTTCCATAAAAAGCTATTCTTGAATGATTTGCCATTTACAAGCATATCGTGATCCT +TCCCCTCACCCTTATAATAATTTCTCAATTCAGTTTGGGTTTCACCAACAGTCAAAAGGT +CCATAGTCAAGGCATGTAGGGATAATTTCCTCATCACACAAGGAATTCTTAATCCACTAG +ATTCTCCAAATGGCATATGCCTCATACATACAGGCATCACCCTTCCATGAACTTTACTAT +GATGCTGCTAGGCCATGAGAAAACCACTGGAGTGATGAAATTGTCAGCTGAGAGAAACCT +TAGAAATCTCTTATCTGGCATTCCTGTTTTACAGATAAGGAAAGTAAAATCCGGAGAAAT +TAACAGCCAGATAGCTCCTCAGTGGCGGAACGGGGATCAGACGTGTCATCTTCTGAATCC +CAGTGCCCTTTGCCTTGTAACAAAACACCACTCTGAGACATTCATATTGACCCAAAGATT +TTCCCTAGTTGATTTGTGAAAAAAAAATGAAATTAATACATTCCACAACAGTTCATACAA +AGAAGCAATACAAATATTGTTGACGTATTATAATTCATTTCCATTGCTGAGAATTTTTCT +CACTAAGAATTCTCAGAAGCTTCATGTTCTACAAAAACTTTCATTGGAATTGGATGTGAT +AAGATAGAATTGCTCTCAGACATACTATTAAAGTAGCCTCTAATATGCTTAATTTACTTC +TGGGAATTAAATGTTAGTAATATTTGTCGAGCATTTACTACATGCTAAGGTATTAGAATA +AAAAGTAAAATTACTCAGAGAGTAATTGGCTAATTTTAAGTTGTTTTCTTACTTGGCCTT +GCAATTATAAAACAAAATACATTTAAAAAATTAAGATGAGATATTAACTTAAAAAGTCTC +GTGATGGCCAAATGTTAAAATGTATATGTGCAGTCGGTAACACACTATAGGAGTTTAGAG +GCCACAAATTTCAATATCCATTTTTACAGGATAACATTTTTCCTCCCAAGGAAGGCAGAG +CACATAAAATTTTGTCCCACTGGAGATATGTATGGATTTGATCCGGATTTTCATATGATG +GCTGCTGGTGGTTCTGAGTTTTAGTAGTTTAACGAAGTTAGGCATTCTACATAATGAAAA +TTATTTGAAAAAAAAAAGTCGAATTACATTCCTAGGCAAATACAAAGGCTTCCCCCACCC +AAGAAAATATGTTAGATACACAATACAGAAGACAATTATATTCTCAGTAGGAACAGATTG +TAAGTGAGGTGTCTATCTTGATAAGTCCATACAGTTCAAGAAGTCTCAGCAATTTGAAAG +CAGAATGGCCTACATTAATTTTTTAAATACATATAAGAAGATCCATAAACTGGAACCTCA +GCACCCTGTGGGAAAAAAATCATAAAACACTAAGAAAGGAGTTACACTAAAATACAGGCA +CAGACAAATATTTAAAATATTAGTATATAAAATAAAGTTTAATTTATAGGGTTATTTTTC +AGAACTCATTTCTAAAATTGATTTAATATAAAATTATTATCTTTACTTAAATTTCTTGGC +AAAGCTCAATAACAAAATAATAAATCATACCAGTACTTGCATTTCATCAAGACAAACAAG +TCACTACTTAACATTAAGCTTGCAAACATCACCTCCACTTAAGACCTATATTTGTTTCTG +CACAGAAAAAGATGGAGAAAGCTAGTTAACCGAACTAAGATTGTCTTAATCTGATACTAA +TAATACAAATACATTTTTATGTAAAACCACACCAATACTTTGAAAGCTTTATTAAATAAA +ACAATTTCTGGGAATACAGACAATATTAATTTCCTCAAAACACAAATTTATAGTTTTTCA +AAGCTGATCATCACAGATCAAGTAGGCTTGTCCTATTAATTCAATATCTACCATTCAATA +TCTACCCATCATCAAAATGCTCAAGTGAAAAGCAACATTCAGTCAATTGACTTACATATT +TTGCCTACATGTTACCAAATATGTATTTATTTAATAACACCTGAGTACAGATGTGGAAAA +TTATTACATTCTTTCTTCATTCATAAATTTTCATAGATATCATCAAGATTGCCTTTGCCT +TTGTGGATATATGTATGAGAACACAGCGAAAGAGAGCAACATTTCTGTTGGCTCTATCAG +GTCAGCTTTTCTAACAAATATTTAAAAAAGCAAAGTTATAGTGCAAGTCTCTTGTCTTGG +AAGAATGCGCTATAATCTAATTATGGAGGAAACAACATGATAATACCTGTTTACAGTAGC +ATAGCCACTTGGTATCTATTTCTCAATTATCAGATATTTACTGAAGCCCTCTGCAAGGCT +TTGCCCTTCTTCAAAGAGATCCAATCCAATTACAGAGATGAGAAATCGACCTATACAATT +TTAACTGGCAATATTAAAACTCATGCCTGTCCACATATCGGTGAGAAAACAGGAACACTG +GAAGTAACAGGTTACAGAAATTTAGAGCCAAGAGCCATCCTTATGGACCTGGGTGGTACC +AAAGGACAACACAAGAGATGTGGTTTTGAGACTGGACTCAATAGATGGTAGGATTTTCAT +CATAAAATAGCTGCTTTAATAGTCATGCCCATGCACCTTCACAAAAATAGTTTAAAAACA +TTAAATCCTAGCCTGGCTCTTCTGCCTTCCATAACTGGAAGACACAAATAATACCAAGAT +ATAAATAATACCAGTTCTTAAATTAATTAATGCTTTTATTTATTTCTGCATTGAAACCAA +TAACTCTAGGAACATATTTTGAGGTAAAGGCATCATGAAAACACATACACACCCATACAA +ACAAACCTTAAATACAACTGGAAGCATCTTGGACTTTTCTCCATAAGCCAAAACCACCAG +TTTTCCCTCTTTCCTTTTCTGAGAAACTACACATATAAAAATAGGAAATATATCCACTCC +TTTTCAGAGATAATGGCTCACACTTAAAACATACCCCGAAGAATCTATCATGAAAGACGA +ATGCAACCAGTTCATATCTGTAAATATAAATTGAGGAGAATGGAATCCTCAGGTGAGAAA +TTATTTCTTTAGTGTTATCTTCTAGTTTCAGGCACCAGCTTTACATAATGGTTTGGATTG +CTGAAGTCCTTATTTGTATTTTTGTGTGTGTGTAAGAACACTCTACCTTATTTTAAAAGT +AAATGTGTAGCTTTGGTAGGGAAGTAGCTATATATTTAATGTCCATTCAATGTTTTGGGA +ATCATCAATTGCTTGCTCTTGTTTGATGTGGGAGTCATGTTTTGTTTAAGTGCATCACAG +CCAAGTTAAAGAGCAGATGTGTGGTTTGTGTCTTTATCCATATAATTTTCTGTTTAGACC +AAATGACATTATAGCTGAAAATAACATACCCTGATTTTTCCTGATGCGTGCAGATCCTCC +AAAGTTTAATAGGATATGGCCGAATATTTCTTCCCTTGAGGTTTCTAACCCAAAACAAGG +TAGGAGCATGTAAAATTCCTACGGACATAAAATCCCACATGTTTGGGGGAAAATCCTATA +TGCCATTTTTAGCACAAAATAAGAGCATTATCATGAATGCTATGTCTTTGAAAGAATCAT +AATTCAATCTTTTTTTCTAATATGAAGAGTGTCCCAAAAATATTAGAGTGAAAGATGAAG +GGGAAAATTAGATGGCATGGAAGTTAAAAAGCCCTTTACCAGATTACATTGAAGGTCAGT +CAGTCCCAGGAGAAGCCTAGACTTCTGTTACCACCACAGTGTGGAGGACAAACAAGACTT +AAAAATGTGTGAGTGGCACAGGCATCCTTTCAATGTCTTCCTCTTATTTTTAAGTCAACC +AACTGGTACCTCAGTTGTACTGAGGGTCTGGGTAAATACATAGAGGTAGTATTGTGACAC +CTAACAGATCTGTTTTCGCTGACTATTGCTCCATATTGACTTGCAAAAATTTGGAGCAAT +CTGTCTCTTTCCCTTCCTCCTTTTTCCTGTCTTCCTCCCTCCCTTTAGCCTCTCTCACAC +ACCCTTTCTCACTCCCTGTCTCCTCTCTCCCTCTCCCCGCTACCTCCTCCCTCCTCTCTC +TCTCTCTCTCTCTGTCTTTCACATCACAGTAAATTTTCCTTGTTGGAACTTTTCCTTTTA +TCTTCTTTATCAATTAACATTCATGTGTTCCAGCATTTAGAGCAATCTGTTCTCTTTCTG +TCCTTAGAGCAGTAATTATTTTCTGACTCCTAATGTCAAAGAAGAAAAAGAAAAAAGAAA +AAAGAAAACAACACTGATAGACAGAAATGTGATTACGCAGGAAGAAAGAGAACTTTTAAA +GGCTGAGCAATAAACTTCATAAGCTGCAGTGTAATGTTAAATTTATATTAACATCTAGCC +TATAGATATATATAGTCATGTATAAATAGGAATTTATTTTAATATAGTATTGTATTATTT +TGCCTTCTTCCTTCTTCAAAAAAAAAAAAAAGGCACATCTTTGGCTTCCACCTTCCTTAG +CTATATACAGGATGTTCCTTTTAAACTCTAATGAATACAGATGGAAAAGGAAATGAGCAA +AAGGAGGAACCAGGAAATAGCTGCTAAGCAAAACAAAATATATTAGTAATTTGTTGAGGA +GTCAAATTGGAAGGGCTGCATTTTCAGTCCTTGATCAGAGTGATGAAATCTAGACTGTCC +TAGATACATATATTACTAGCAAATAGAATTATCTTAATCATCTGCTCCAAATGAATTTTT +TCAAGTTTCTGCATACATATATGAAAGAAGAAATACAGATCAAGCTTGCCCCTATTAGTA +TAATTCTAGGAGGATTCAGAAGAGGTTTAGTGGCTTTATTCCTTGGCAAGTTCAATGACA +GCATCTTCAGTGAAATGTCACTCAGTATTTCCTATTGAATTTCATAGTTCACAAATTATA +CAACACAGGCTCTAAGACAACACTTCTCCACAGTGAGTTTTGAGCTGAACAAGATTATGC +ATTGTTCAAAACCTGAAATAGGCCCATTTAATTATTTTGCTGTGCTGTCTGTGAGAGTCA +CAGGACAAAACACTTTCAGAAATATCATTATGTAATACCAGTTGCACTTTCTTAGAATGT +GGATAATGAGTTCAAATGAATCTATTGAGAAGCAGCACAGTTGAGCAAAGTTCTTAAATT +CTGAAATTTTAGCGAAAGGTGCACTTTGTAGCAGAGGCCAGTTCTATGCAGCCATAATTT +ATCTTGTCAGCATCTGCAAAGAACATCAGGCTCTGTTCTGTTTTGGCTATTTTCACAAGC +AACTCTTCATGAATAATTGGAAAAGAAATGGCAGGCAAACATAGAGAGAAATCTCTGCCA +TTAACAAGCTGATATCATCAAAAAGGTAACAAATGCTGAGAAGGCTACAACTTTTAAAGG +TATATGTGTTCAAGATGACTCTGAGATAGGCCCAAATGCTGCTGAATGGCTGACTATTGG +GACTGACTTATGTTCTAGGATGCCTAATTAGTTCAACAAAAATAGTCTAAATGGTGTATA +TGTCGAATAGTTTATCATGACACAGAATGTCATGGTGAACCCAGGCAATGATAATGTCAA +CTGACAAGACAACTCCTACTTTAAAAGATTGACAGTAGGGGATCCTACTATCCATATTGT +TATGGTAACAATCCTTGCTTCACTGGATTCTTGATTTAAATGGTAATGATTTTTCCCTCT +GAAAAGAAAACTTCTAAATTGTATTACTGACAATGTTGAACCATTTTCAGCCAAATACAA +GCCTTACTTTGTGATTGAAACAAACTCCTAGAAACAACAGATACAAATAGTCTCTTAATT +TAGGGCTACTTTTCAAGTGGGTTGGTGATAAGTTATTACAGTTTGAACGTTTCACTATTG +TTTCTAATTTACTGTTCATTCTTTTAAACCTATCCAGTTGCTCCCAAATTAGCTTTGTCA +ACAGTTTCTTCTGTTCAAGTTGCAAACCACAAGAGAGGTAGGAATTCTTGGATTCATACA +GTGATTTCATGGTGTTATGTGTTGTGAAACATTGCACTGTATGAATCTGGAATATCTGTG +AAGTGTACCCATCAGCTTATTGGTGAGGCATGTTGACTAATATCAATCAATGCATCGAAT +AGTACTGAGAATCATCTGTAAGAAAAAAAAATGCTTCACTCAGAAACTTGACTGCAATTA +AAAATGTTACATTTGTTTTCTGAAAGATTCATGTGTGAATAAGAATTACAATGGTTGAGG +TTCCTGTTTAGAACACGAATGTTAGAGCACTATCATGGATACTCACTTGCATTGAAAATA +AGGAAACCCACTTACAGTGAGTTTCAAGGATGCTTTTCATGAGACCAGAAAGGCAGGTTC +CATGTATGGTGCCCATTTCACTTTGTGACAAATGAAACACCTTGGAATTTATGCTTCCAA +AAAATTGTTTCGAATAACTTTGAAAAACACAAGTGAAGATCTGCACTGGATTAAGTGTTG +CTTAGGATCCAAAAATAATAGTTATATTACTTTGTTTAAATGAAAGTGAGCAGCATCTCA +TCTGTGACTCATGAATGGCCCATTCCAGCTAGCATCTGTCATTCACAGAATGAAGATTTT +TCAGGAAACATGAAGACTTCTGTTTTTATTTCACCATTTTTTCTTTAAATGTCCTGTGTA +ACAGGTGTGTCTTGTTTTCCACCCTTGACTGTTGGGCATATGTCACGTTTTAGTTTTGTT +TTTTGTTTTTTCATAAAACACCTCTTACAAAGAAATGCATTTATTAATAAAATCTGAACT +TAGTTTGACCCATTTGGTGAAAATGACCATAATGTTTTCCTATTCTTTATTGAATTTAGT +CATTTCCTAGATTTTAATCAATGTTGAATTTGTCCTTCCATGGCATATAGAGAAAAAGTG +GAAACTGGTCAGGAAATGGGAAAAGGGAAACCAAGAGTATTTAAACCATATGTCAAAATT +TTCTCAAATGTGCTTTTAACCGTGGAACATAGAAGATGCCAATTTGGGTTGAGGGGAACC +CAATTAGGTTTGAAATTTTTGGAAATAAGTCCTGTATGAGAAGAGCAGATGCAGGCTCAG +AGGGTAACAAATCAATTTGGGTATGTGGTGTGTCATATAGGCAGTCACTGAAGCCATCAT +AGGGATGCCATATGGAAAGAAACAAAGGAGGTGAAGGAGAAAGGAAGGAAAAAGCACATG +CAAAGTTCATCTCTTTTCTGTCATGTCAAGCATGCTAGATATATAAGAGGCCTCTGAACC +TGGAATTTGAACCTGCATCTCTAGTTTCTTGAGGACACAGCACCAATGAGGTCCAGACAC +ATTCCTGGGGGCAGGGAGAAGCTACCCAATGAGGTAGACTTACCAGAGACAAATTCACAT +CATCGTCAAATGATATGTGTGGAAGAGCTTCAACAGCTACATAAGGATGCAAGACAGGAT +GGTGGGTGGGGAAAAGACAAGGAAAATGCTAGAGCCTCTTAATTCCCAGAATCACTCCAT +TTAATGCAGTGAAGGGAAAATTCTTCTTAGAGTTCCAACTCCTTCACCTTTGAGGTCTTT +TTCTCAAATTCTTTCTTTTTGAATGTCTAAAGTGAATTTTAATCAGCTCTGGATTTGAAT +TAGCTTTCCTCATTTGGCCAAAAAAAAATCTACCTGTTCTAATTGTGCCACATTCATTGT +ATTTTATGTTATATTTACAGAGACAATTTACTAATGTAATTATAGGCAACATGGGGAACA +GTAAAAACGAGGATGCAAAGGAGAAATTGAATCCCCTCCTCTTAGTAACATTCTTTTTCT +TTCATTCTCTGTGTCCAACCTCTTGATTTCCTGGAAATCTCATCTGCCCAGGTCTTCCCC +AGCCAGTGTCAGTCAAAAGGAACCTTTTAAACCTTAGAGGGGACTTGGTCCTTTCCTTAT +CTAGAAAGTCAACTTTGAACCCTTCCCCTTGTAAAACACCTCTAGCCTTCATTGCTCTTA +ACTGTCTAGGTACTAAGTACTTTATCACAACTGCCTTCTATGTTTCAATATATCATATAT +ATTACACATATATAGTATTTTTTCTATCTTCCCACTAGAAGAATAGTACTCAATGGGGAT +GTGGGTGGATTTTGCCCCCCAGGGGACATTTGGCAATGTCTGGAGAAATTTTTGTTTGTC +ACAGTTTGGGGGTTGCTACCACATCTAGTCATCTAGTCCGTAGAGGGCCCAGGGATGCAT +CTGAAAAGCCTACAATGCACAGGACAGCCCCATACAACAAAGTTATTTGGCCCAAAATGG +CAATCGTGCCAAGGTTGAGAAACCCCACACTAGACTCTGAAGGCCTGGATCGCATTCCCT +TTGTCTTCTGGTACATGATGGCTGTACGTGGTACAGGGTAGTTCTCAATAAATATGTGTT +GCCAATGGTTGCCATGCCACATTGTGTATACATACAGCTAAAGACCCCCTTTAGCTTTGC +TTATACAACAGTAATAAAAGTTGTCTGAAATGCAATTTGACATTAAAAACTATATAAAAC +CACAGCAATTTTCAGAAACCTGCTTTTTCTCTGCCTAAGCTGATCTGTTAATAGACATGT +AGTGAACTCTCAGCTAAAATAATCACTAACTCAGCTGTAGCTTGTTCTGTGGCTACTGTT +TTTCTAAACTCCTTAATATATAGGATATAGCCAGATTCTCTTCAGGAATTCAAACGATGA +AGGAATGAATTTAAACATAACTTTTCTCTATCTTCCTCTGTTCCCCAAAGGAAGGGGTCT +CAGGATCATCATTCATTCATTCATTTGACAATATTTTTTCAGTGCTTAGTGTATGCCAGG +CAATATCTTAAGTTCTGTAGTTATAATTGTGCACAAAACAGACACAGTCTGCCCTTGAAT +ATTTACACTCAGAGAGGGAGAAATTATTTTTGCATATACTTTTTGAATATTATAAATTCT +ATGAAAAAATATAAACAAGATTAGGAAATTGAGGGATTAGGGAATGTGGGTGGGGCTATT +ATCTCAGATTAAATGGTCAGAGAATTTTCTTTGAGAAGATATTTTAAAAAGAAATGGGGA +AGCAAATAATGGAGATGTCTGGGGGTATTCCAGACCAGCAAGTGCAAAGGCCCTGGGAAG +TGCTTGGTGTGTTTGAAGAGCAACATGGAGGCACTGTGCCATGAATTAGGAGGTGAGTGC +TAGCAATGAGCCCCCAGGGAGGACAGGGGCCAGGTCACTAGAGAATGAATGAACTCCTCT +TTTATTCTGAATAAGATGTGAAGCCATTAGAATGATGAGCAGAGGCATGTCATGACCTCA +CTAAAGTTTTGAAAGAGTCACTCTGTCTGCTGTGTGGAGATGACATTATCACAAGGGTTG +AGGCCAGAAGAACAGTTTGGGGATGATGGCAGTAATCCAAGTAAGGGCTGATGATGCGTC +TGAGGAAAAGGTGGTAGAGATGGTGAGAGGTGTAGGCTAAGCAGTTGGAGGAATGGAATA +GTCATGTAGTGAGATGGAGAAGCCTGGGTGAGTAGCAAGTTTAGGAAGGCAACCCAAGAG +CTCAGTTTTGAACAAGTTAAAGTTGAAATGTTTATAAAACGTCCAAGTGGAAATTCTTGG +AAGGCAGTGGCACACAATGGATGACTCTGAAGGGAGTCTCACTAATTAATTGGGGAGTCA +GTCCACCCTGGAAATAACTATTTTGGAATGGCCTGCATATAGACCATGGGGTTGGGTAAA +AATCATCTAGAGTGAATGTAGAGAACAAAGAGGTCCAAGGATTAAACCTTGAGACATTTG +AAGAGATGAGGACAAAAAGCAAAAGAGAGAAAAAAGCAATGATGGGTAAGGAAGAAGAAG +AATCAAGAGACTGTGGTGGCCCAGAAGCCCCTGCTTCAGGAAGGATTACCAGGCAGATCT +GGGGACCCCATTGAGGTTTATGGTCATGAACTTCAAATGAGACTTGTTTCTAAATGGCTG +GAGAAAAACTAGCCACATTTAGCTACTGGGATATGAGCATGAAGAGATGAAAAGTTGAAT +TAAAAAAAAAAATTAGATTCAGGGGGTACATGTGCTTGTGTGTTTCATGGATATTACATG +CATAATGGCCGGGGATTGGGCTTCTAGTATACTTATCACCTAAATATTGGATTTAGTAAT +TACCAGTAGGTAATTTTTCAACCCTCAAACATCCCCCATTTTAGAGTGCTCACAGTCTAT +TTTTTCCATCTTTATGTCCGTATGTACCCTTTATTTAACCCCCACTTATACATAAGAACA +TGCAATATTTGATTCTCTGCTTCTCTGTTAGTTCACTTAGGATAATGGCCTGCAGCTCCA +TCCATGTTGCTGCAAATGACATGATTTAATTCTTTCTTATGTCTGCATAGTATTTCATCA +TGTATATGCACATTTTCTTTATTTAATCAACCATTGGTGGACACTTAGGATGGTTTCATG +ACTTTGCTATCATACATAGTGCTGCAATAAACATATTACTGTAGTTGTCTTTTTTATATA +ATGATTTATGTTCCTTTGGGTAGATACCCAGTAGTAGAATTGCTGGGTCAAATGACAGTT +CTATTTTTAGTTCTTTGAGATATCTCCATACTGTTTCCCATGGAGCTTGATCTTATTTAC +ATTCCCACCAACAGTATATGAGTATTCCTTTTTCTCTACATCCATGCCAGCATCTCTTGC +TTTTTGACTTTTTAATTACAGTCATTTTGACTGGTGTAAGATGGCACGTTAGTGTGATTT +TAATTTACATTTCTCTGTTGATTAGTGATACTGAGAATTTTTTCATGTGTTTGTTGGCTA +CTTGTATGTCTTCTTTTGAGAAATGTCTGTTCATGCCTGTCCCAGTTTTTAATGGGGTTG +TTTGTTTTATTCTTGTTGAGTTATCTGAGTTCCTTGTAGATTTTAAACATTGGTCTTTAG +AGGCATAATTTCTAAATACTTCTCCCATTCTGTAGGTTGTCTGTTTATTCTGTTGATTAT +TTATTTTGCTATGCAGAAGCTTTTTAGTTTAAGTCCCATTTTATTATTTTTGTTTTTGTT +GTATTTGTTTTTTCGGTCTTCATTATAAATTCTTTGCCTAGGCTGATGTGCAAAAGAGTT +TCTCCCAGGTTTTCTTCCAGGATTTCTATGGTTTCAGGTCTTATATGTAGGTCCTTAATC +CATCTTGAGTTAATATTTGTATAGGGTGAGATAGAGGTTCAGTTTCATTTTTCTGCATAT +TGCGAGCCAGTTTTCTCAGCACTGTTTATTGAATAGGGTGCTTTTCCCCATTGCTTAGTT +TTGTCCACTTTATGGAAGGTCAGAGGTTGTAGGGTATGTGGCTTTATTGTTGGATTCTCT +ATTCTCTTCCATTGATCTATGTGTCTATTTTTGTACCAGTACCATGCTGTTTCAGTTACT +ATAGCCTTGTAGTATAATTTGAAGTCAGGAAATGTGATGCCTCTGGATTGGTTCCTTTTG +CTTAGAAATGCTTTGGCTTTGGCTATTTGGGCTTTTTTTGGGGGGTGGGGTTCCATATGA +ACTTCAGGATTGGTTTTTCTGATTCTGTGAAAAATGACATTGGAAATTTGATAGGAATTG +CACTGAATTTTAGATTGCTTTGAGTAATGGGTGATTTTAACAATATTAATTCTTTCAACC +CATGAACATGGGAAATTTTTTCATTAATTTGTGTTGTCTACAATTTCTCCTATCAGTGTT +TTATAATTCTCCTTGTAGAGATGTTTCATCTCTTCTGTTAGCTGTATTCCTAGGTATTTT +ATTTTATTTTGGGGGGCATGTAAATGGGATTGAGTTCTTAATTTGGTTTGCAGCTTGAAT +ATTATTGGTGTATAGAAATGCTACTGATTTTTGTACATTGATTTTGTATCCTGAGACTTT +GCTTAAGTCGGCAATCAGTCTAGGATTCTCCTACAGGATCTTTTGGCTTTTCTAGGTATA +TGATCATGTTGTCAGCAAACAGAGATAATTTGATTTCCTCTTTTCCAATTTGAATGCCTT +TTATTTCTTTCTCTTGCCTGATAGCTCTGGCTAGGACCTCCTGGAGAGTTGAATTTAACC +AGCATCAACTTTTAACTGGGATCAAGATTTCCTTATAATTGGAGGGTGGAAGGCCAAGGG +AGTATATAAAAGGAAGTGATTATAAGGATTGGACTATGGATACTATATAAGAAGAAATGG +GAGGTCATGGGAGGTCAGTGATTTGAAGAATCAAATAATTATTAAACTATTAATATCATC +CCTTCAGAAACTTAGTAGGATAATGCAACTCAAGCTGTACCTTAATAGGTTCTGTGCCTG +TGTGGAAAGACCAGGTATTAAAAAGTAGGAAATTAACAGAACACCAGAAAATAATATAGC +AGTTTAAGAGTCATATTTGAAATACTTTGCATTTATATAGTACTCTCATGTTTTTCAAAT +CACTTTCAAAGATCTGTTTCTTATTTTATATTCTCAAATATATTATGGCCAGAGATGACA +GCTTTATCAAAGTCTCAGAAGAGTACTAGAAGTCTTAAAAGAATCAAGTTATTATTACCC +ATTTTCTACATCATAAAACATTTTAATGCTGATAAAACATTTAAAGTATCCAGTTATCAT +TTGAAATAAATTTATACTATTGCATGTTTAGCTGAACATGATTTCTTATACAATTATTTA +TCATTTCCTTTCTAAATTAATAAATTAGTTTTTAAACAAGACCCATAAATTGTTAATGTC +CCCACAGAAATGTGTACTATTCATTAAATTCTAATAATAGTAGTGATAATATCACATTTA +ACATTTTTATAGAGATTCATGGAATGGGTCTTAAACTGTTGAACTTGGGTATCTTACAGA +TTTGGTTTTCTTACTCAGATAAAGTTTTATCAGGTAGATTAAAGCATGTAGTTCTGGCCA +TTGGGCAGACTCTACAGAATCCTTTAGGTACCCACAAAGGAACCATAGTATGAAAAGTCA +CCAGCCTTATTCTCTACATTTCCCTAACTTCATACCTTTGCCCACTCTTTACTCTATTAC +TTTCACCTAAAATGCTCATTCCCTCCTATTTTGTTTTGTTTTAATAAACTCTACCTGCCC +TGAGGAAGATTCAGAGTGCACATCCTGTAGGACATTTTTTCTAATTCTCCTCCTGTTAAA +TGAAGTTCTCCTTCTACTTAGATTGCTTTATGTCACTGTTTTTTCTCTGCACATACTATT +TTTTTCTGGTTATCTGAGCATATGTTTTCTTATTTACTAAATAAGCTTCCAGGCCACAAG +CTTATATGTAGCTGTAGAAAGCTCCTAGATGAATTTTTGCACATAAAAGATGCTTTTGAA +CAAAGCTCTATTAATTAAATTAGATGTACCAAGAACCAACCCGGGTTAGGGAACATGAAG +AAGAACAGCCAATAAGAGACCTCTTCCAGAGGAGGCGACCCAGGGGCAGGGCTGTTATTG +GCCCTCCTCAGGAATTCCAGGCAGTTCTCAAAAAGTCCTTGGGAAGCAATTAGGTTTGAG +AATTGGGTTTCCTTCCTTCAACCACTGCTCTCAAAAGGCTCTAGTCCTGAAAGATTGTCT +TTATTTCAAACTCTCAAACATAGAAGGCTCTAGAAGCTTTTCTGACTCCCTCAGAAGTCA +GTAATGCCAGTATAAACAAGGCGTAACTCTGAGCGGTACAGAGGATTGGTGGGAAATGCT +TGTTGTTTTACAAGAGATTTTAATTTAGTAATCTGTAACTCTATGATTATTGGTGGTAGT +ATTATTATTCACTTGGCATGCCTTTACTACTAAATTTATATGGATATTTCCTTACACTGT +CTCCTACATTGGAGTCTCAATGCCACCTTCTCCCAGTACTCTCCCTCTCCTCCATACTCG +CCTCCCCTCTGACTTCTTCCTGTCCTCACACTCACCCTTCTCTCCCTGTTCACGTACACA +TGGTGATACAGCTCACCTCAAATAAACGAAGTGGTTTGGCTTCAGCATCCCCCCTTTCTT +CTTGCCTCTCTTTTAGCAACTGGGGTCCCGAAGTTGCTGACACTGTTTCTGGTTATCTTC +TACTCTTCACCATTTGAGTATCCTCCTCTGCTTCTATCCAAATTTGATTTCATTCCATCA +GGACCTTGTTATCAGCTTCCTATTGTAGTAACTAGCTCTCTAACAAATGAATATGAACTT +TTCTGATGAGTGGTAGCATATTAATTTTTTTAAAAGTTTAAAAGTTAGCCACCTCTTATT +ATTATTTACTTGACAACACTTACTCATTTTTACTCTACTCATCAAAATATAATATTTGAA +AAATTTTATATAGGCCAAAATAGTAACTCAACACCTAGCCAAGTTCCTGACACATAGGTA +GACCAACTCAATAAAAATATTTATTGAATGAATGAATGAAAGAATGAATGAATGTGTTCA +AATAATGACTGTGCTTGGCTTTCTAGTGGGATAAAATAAAAGCAAGACAGATATTGATGC +AAGAAATATTTTTAAACAAACAAAATTTGCAGTATCCTGGCTGACCTTCCTTATAAATGT +CCAACTAGGCCTACCCTCATATTCCATGAAGACAAAACAGATACCCCACCTAGTTACCAC +TCACACTTTTGTGATAATTATTTCTACCAACAGAGACTTTGTCATTATCATTTATTTTTA +AAAGGTTGAATTGGATTTACAACTTCTTTCTCTAGTTGAGATGCAAGAAAGAAGAAATCT +AGTCACCCTCCACCCTTCCCCAACTACTCTCATGCTCTTCTTCATCTCCCTGTCTAGTCA +TTACCACCATCACTCCTAAGCCTCAGAGACACCTCTAACATTTCAGAGAAACCAAGGAAA +AGAAAGGTGGGGTTACAGTAGCTACCTAATTCTTCTTTTGTAGCAAACTATTCTTGAAAC +TTAAGAGAAAAGGAGGGAATCTTAAAAGCACCTTTTCGCACAAATTATCTCCCTGCTTTT +TTTGTCTTCTCTCACACATATACATACAGATTTGGTCTGAAGAAAGGCTTAAGAAAGCCA +TCTTCTCTTAGCATTGGGGAAAAACAAAAATAAAGAATTGTTTAGTTGTCTAGAACTCTA +TTAAATTTGCCATGATGTATATGAAACCCCGACTGAGTTGCTGTCTTGGCATGATGTCAG +AGAGCTAAAGGAGCCATGGTGATGGTACTTAGACTCTCAATGCTCACACAGTCCCCTCTC +ACTTTTTTTAAGGCTGAAAAGATGAAAACAAGGGAAATGGTGCAAAGACACTAAAATTCT +CCATCTGCAAAAAATAAAAATAATAGACTTTTTCATCACTAGAAACTGAGGCTTCCCAAA +TTTTAAAAGGTGTACACCTGCAAATGCTTCTGTTCATTTTGTCTGCCAAGAATTAACAAT +CTTCAGTCTTGTTCCGAATGTCCGACCTTTCTATCCTGCTTGAAACAGATGCTATTTCCG +TGCCAGTCACAACCACCTGTTGCCACCATGTGTTGTGTTGAATCACATATATGTAATGCC +ATTCCACCGTCTTTTCTCCATCCCTCATTTTACCCAAGCATGTAGTATGCTATTACTCTG +CTACTGTATACACTCTGTATACATTTCTGTTCTTCCTTGCAAGATTGTGAATGCTTCGGC +CACTCCAATCGATGCAGTTATATCGATCTGCTAAATACAGTCATTTGCGTGAGCTGTAAA +CACAACACTAGAGGGCAGCACTGTGAGTTATGCAGGCTGGGCTACTTCAGAAATGCTTCT +GCACAACTGGACGATGAGAATGTGTGCATAGGTCAGTTCCATTACAATTTCAGCTATTCT +TCTGTGCCTTTTGAGCTACGGGGAGATATTTAGGGTGGAGAGGCTGGCGATTTGCACCGC +GGTTGAGCCAGAATGAACTTTCTCAATGTAGAAAATATCCTATGGTAGATTTCACTTGTG +ATTTCACTTGTATTGGTTGAAATCATAGTTGGGGGATATACTTTGAACCCTTATGTTGTT +GCTTTAAATATGATGATCTCAGAAATCATGTTAAAGAAATTAAGAATTTTCTTTCTTCCC +GTTTTTTGCTTTTGTATGAAATTGTAAAACCTGATGATTCTGAACTGATCTTATAGCCTT +AAACTTAAGGCTATACATTCAACTTTCAAAATAGAAACTCATTATATGCGATTTAATTAT +AGATATGAAAAATTAGGGTACAGATTCTTGCATATAATTGGTGATCAACGAGTATTGATA +GATTGAAAATGTTGCTATTTGAGATTGAAAATGACTAGCAACTGGAAATGTAAAAGTTTG +TCTGACTTCTTCATCCATAGCAATGAAATTCCATTTATTGAATTTTCCTACAGCTCCCAA +AAAGGAGGAGTAATTTCTCAAAAGTATTCTAGGCAACTAATTATCTTAGCCCTGGAAAAC +TGCGTCCACAGAGGCCCCTGAGCACTTTCCCTTCCCTCCCCACCAATGACTACTGCTCTT +GGCACCTAGGGAGGACCAGGCACCTTTCCCACCCAGAAAATCTCCTACCTTTTACATAGT +GAAACCTGTCTTTAAGAATATGGGGGTGCCAATGGAAAAATAAGAAACAATAAATGGAAT +TTCACTTCATAATTCACTCTGAAGCAATGCATATATTTGAAATGCTGAAAAATATATGTG +TAGCCATTACCACACCAGTAGGTAGCTATATAGGCACCCAGTTTTAAAGGTAGACTTTTT +CACATTGAGGTACGTTCAATAGGATACACAAGCTGAATAATGACAAGCAATCTTTTTATC +AAGAAAAGAAATCCAATTCGTATTTCTGTGATCATTGTCCTCTGATTGGATCGTCAAGAT +CCAAGTGTCACAAAAAAAAGCTGTTGAGTTGTTTTTAATCAAATTGGGCCAAGTATATAT +AATACTGTTGGTGTCTACAGTACTTTCTGTATTTCAGAGCATCTCCTTATTTATTATTTG +TCAATTAGGAGAGAAAGTACTGGACTTAGAGGCCAGAAAGCTAGGCTCAAATTTCCGTTT +GCTAGCTCATGGCTGTGTGCCATAGGTAAGTCATTTGAGCCTTCTAGTCAGAAAAGGATA +AATGGGATGCACAGGAAACCCTTGGTCAACTGTGAACTGGCTTGCAGATGTCTTGTTTTG +TTTTTACTTAATCCTCATTAACAAAACAGTGGGGTAAGTATTACACTAATTGTTTCCCCT +GTCTTGTCATTGAGAAAAGTAAGGCAGATTGACCCAAATCTTACAGCAAAGGGTTTCTGA +CTTCAAAGCTTAAACACTTTCAACCACTGACACAATTAGCAAAGCTAAGCTTGTCAGACT +TTTACTTATGGTATGTGTTTTGGATGACAGCAGCAATTCCACTCTGAGTTTATGAACAGA +AGTTCAATTGTCTTCATAACACTTGGGTTACAAAGATTTGAGGATATTAATGAAAACCAA +AAGACATGTAGTTGTCTGAATTTTGAAGGCAGAGTACATTTTACTGAATGTCATTTATAA +AAATATATAAATGTCATGCTATAGATAGGTAAACACCAGAAAAACTAAAATAAATAGGAA +CACAGGATAAAAAACCTAACCATTTTTACATAAGATTAAAATGTTTTATAATATTTAATA +TGATTTTAAATCAATCTAAAAAAGTCCTTAAAAGGAAATATTTTATTCCATAAAATTTCT +CTTATCAGGTAACTTAACAATATCACAATATATTTTATTCAGAGTATTTTATTATTATGA +AGTTTGGCCTTTTTTCCAGTTCTGAAGTAAACTGTGAACTCCACATCTGCTTCTTTCTAT +CCAGTTTTAAGAGGTATAGTTCAGTTGTAAATCCATATTTGATTATCCACAGACTAGAAA +ACAATCCATTCAGTGTCTGTCTTTTAAATCAGATAAACTACAGAAGAAATATGAAAAAGA +TATCAATTTTGTATTTATTTTTACTTTTAAAAATCAAGAAGAGTTTTCCTCTCCATTTCT +AGAAAGTTTATTAATTAAAATTATAAACTTTTGGAAAATTCCATTTTATCGAGGTAAACC +TGTTTCTATTTAGTATTTTGTACTTGAAACCAAGCGAAGTACTTGGTGAACACAAAGGAG +TGCATTCCTAGGTACTATTAAAGTTAGCTACATTAGGCCAGGTGCAATGGCTAATGCCTG +TAATCCCAGCACTTTAGAAGGCCCGGGCAGGTGGATCACTTAAGGTCAGGAGTTTGAGAC +CAGCCTGGCCAACATGGTGAAACCACATCTCTACTGAAAGAGATAAAAAATTAGCTGAGC +GTGGTGGCCTGTGCCTGTAATCCCAGCTACTCAGAAGGCTGAGGCAGGAGAATCAGTTGA +ACTCGAGAGGTAGAGGTTGCAGTGAGCTGAGAGAATAGCGCCACTGCACTCCAGCCTGGG +CTACAGAGCGAGACTCCATCTCAAAAAATAAAATAAAATAAAAAGTAATATTAGCTAGAT +TGTTCCCTCACCCACCATAATTTCTTAAATTATTGCCCTTTTCTAAAGAAGAAAATTGTG +TTTCAAGAATGAATAGAAAAATTTAGCTAGCTGATAGGTACTAAGGTCTATCTTTTATCT +GTAGTGCTTATATGCACACAATGAATTAATAACAATTTCCTTAAAAAGCTGTAGATTTCA +CTTACCCTGCTTGAGGCGCTGAGGACAGTGGTACTGGGGCTGCCTGTGCACTAGGCTGGA +GTTTGCCCTCTCAGGGCCGTTGGAAGCCTCTGGCTCCTTTGCTAAGGTTTGCCCTATGAG +ACAGCATGAACCTATTTGCTATTTTCCACAATTAAGATTCCTAAAGGGCTTGCGGCAGGA +CTGTTAAATTCGAAAGGATACATCACAAGTAATTGAGAGTTAATCTTAATACCATTTTGT +ATAGAAAGCACTAATGAAAATGAAGGGATATTTACCCCATTCACTTTCACAGAATAAGGC +ACTAATCTTGGAAACTTTGAACTTCATCTAAGTCTCATCTACATTAAAAATAAAAAAAGA +ACACTTTGCCAATTCTTTAACAACTGACAATAAAATTCACCACCCTTGCTGTAAAGGAAC +AACTCATATCTTTGACAAAATGTAGGCTCTGTGTGATGAAATAGATGTTGTAAAATACTT +GCATCATTTTATATTATGGCAAATATAAAATGCAGCAGGCTATTCCATGTTGCCACAGTG +ATTGCTGCTTTGTAATTACTGGTGAATTTGCCCATTTTTTCTACAAATTCCAAACACAGC +CATGTCTCCAAAGATACATGTAATTACCCTGTAATGACATAGCAATTACATGAAGATGAC +ATCCTTGCATGCTTCTGTTTCATGTAAACTTGAGCATTAAGCAGGAAGCTAGAGGATATA +TGGTTTGTGACCCTGAGTAATCACTGTTAATAATCCAGCTGACAAGCTTTGCATCACAAT +GAAACAGAGCTCAGCAGCTGCTGCTAAGCATTTCTTAAAATTATGATGTATAATTTTTAA +TTCCCCTTTGAAACCCATGGTTGGGTAATCAGAGGTACCTTAAATAGAATAAGGGGAACA +TAAGACACTTTTAATACCTGTAAATCAATTCTAGTATAACTTTTAAATGAAGCACCCCCT +GCCAGGTATTTTACGTTGCTTTGTAATCTAACAGTCCTGCATGTTCTTCCTAATTTCATG +GAATAAAATATGATCCTCCAAGACTCTTTGCATTACTCCAATATCCACCATTGACCATCA +TTCCATAAATGACACTTTTAAAAAACTGAATTATTTGTTACATAAGGTGAAGGGAAGGCC +ACACCCCTTCTTGTCCTTTATTTTCATGACTGCAAAACATTACACTTACCCACATTTTCC +TATGACAATGACTGGGATATATTATGGTTTAAATGTTTTACTGTTTTGTTTAATTTTGTT +TACATTTTTTGCCTCTAAAATCTTATATTAATTAATGGTCATGGGCTAATTGACTGGAGG +AGTATGTGAATTCACGTTGGCCAGATGTAACTCTGCTTACTGGCTTACAAAACATTGGTG +ATTTATTGTCAACTTACACACTTTAAACAGTAAAAAAAAAAATTACAGTTTCGATATAGG +TACAAATTTATAATGTGCCTATGTACAGACAAACATTAAAAGCTTTCACAAAATTAGTAT +TTTAAAATATTTTTAATCTGCTTCCATATACACATGCATATTAAAATAGAAAATGTTAAT +TTAAAATAAAACTCTAGTTGTTAAGTACAAACTAAGCCAGGCAAGGAGAGAGCATTTTAG +AGTTTATTAAGTTTTATTTTTACCTACATATATAACTATTCATCATATAAATGTTTGTTT +TATAAGAATGCTGAACTCGAAACCTGACTTAATTAGCATAAAATAAATCATAATTCTAAG +GTACTCCACATTTATTTGAAGAATAATTAGTGTCTGTGACATAAACTTAGAATCAAACCC +CTAGACCCATCTATAAGGCTAAACCCTGAATCCCCATAGCAAATCTAATATGCCAAACTT +GATTATATTAAACTAAATTTTCAAGACTTCTCTTGGTTAGTTGGATGGTATAGTTTTATT +TGGTTTTTCATGAGGGAACTGCTTAATGTACCCATTTTTAAATAATGGAAACTGAGAGGC +ACAATAACTTCCTCAAAAGTATTAGAAGAGTAATGAGGAAAGAAACTTTAGCTCACAGTA +CCCAAAAGCTGCCAGCTACCTGCACTATCTTTCCAGCTAATAGAAGCCTAAAGGATATCC +ATTTCTGGTTCAAGCTTTAAGCAAAATAGAGCTTCAGAAGTAAAAATATCCTATATAAGA +ATGTGTGAGGAATCAAGAAAACACTGTATTCACCTTTTATTGTGCAAAGCTGTATTGTCC +TGCCAGCAGACATTATAATGAAAAATATACATCTTAAATTATAACTATGTTGAAAATTAT +TTGGGGTTACAAAGTTTATTTTTCTTTCATGATTGTTAAGCTGGGCTGCATAAAAGCTGC +ATTAATATGCCTAGCAAATACAACATCTAAAGGCTTATCACAAAATGGTATATGCATGAA +TAAGTTAAGATGCTGTCCCAAATCATAAAGTAAAACTACCTTTGAATGAGCAAAGTGCAT +TCATATTGTACTTTTAAAATGTTCAGCAGTTCTCAAATATTGAGTGCAATGGCTAAGCCC +ATTTGAATAATTTAAAACACATTTTACACTGATGGCATATTGATTTATCCTTGATATACA +AACTTCTCATGGTGTTTATTAAACCATCTAAAAATATCCTAACAAATGGAATCTCCATTA +CGATCTGTTACCAGTGAAAAGCATGTCTTATTTCCTTGGAAGTTTTCAGTTGATTTCCTC +CCATATCATAAAAATGATATCATGGAAGGCTAAGCGAATAAATAAATGGTTGTGAAATAG +CCATATTTGCCGAAGCATTTCATTAATGGACATCTTTCTTTAAGTAAGTGATGCATTTAA +GTACGTGACGCTCCTGTGTTGATAACCTGTAAGCCATGCAGACTTGTCTCCAGCCTGTGT +GTTGTCTTGTTTCTACAGAGTGTTATTGTAACCCTTTGGGCTCAATCCATGATCGTTGTA +ATGGCTCAGGATTTTGTGAGTGTAAGACTGGAACAACAGGGCCTAAGTGTGATGAGTGTC +TGCCGGGAAATTCCTGGCACTACGGCTGTCAACGTAAGTAACTCTGGGAGCTGCCCTCTG +CCTGCTGCAGCATGGCTGATTTCTGCTTGGCTAGGCCGGTGCGTGCAGCTTCTCAGAGCA +GAAAAAGATCCAAACCGCTGACAAGTTTTAAAAGCTACTTAATGCTGCGGCCAATGTATT +GGGAGAGCAATCCATCAGCTGTCCAACTGGCTTTTTTGAAGCCCATCTTCATCCCCTCAG +TTAGCTGGAGCAACTTATATTGAAATATTGTATGGAGATCCATATACCCGTCCAGACCAT +AAATTAAGTGACACAATAGGGACCCAGCGTGGAAATCTTCACCGCAGAATGAAGGGTGAT +GTGCATGTGATTAATATATTTCTTGAACTGAAAGTTACCCTAGAGCTCCAGAGTTCATAA +ATTAAATGATATCTACATAACTTATTACTACCCTTGCTATCATACCCATCACTGAATCTT +AACCAAAAACCTAAAGGTAATAAATCTAAGGAATATTTAAACGTGGGGTAAAATAAATGG +CAAAAATCGATATTGATTTTAAGCCTCTGAGGTTAGGCACTATGCGAGGAGCTGTGGACA +AATGCCATTTGGTTCAGCCTCATTTCTCTTGAGATTACCAGGTCTTCAAAGCTTGTCAAG +GCACGTGGCATGTCAGTGTGTACAAGGAACATGAATTATAAAATCAAGGCAGAAGGTTCC +TTCCGTCTTTTATAACCTTTTCTGCTTTTGAATTCCGAACTAACTTTCCATTTCATCTAT +AGACAGGTATTTTGCTAGTATTAAAGCACCACAAGACATATCCTGTGTAGCAGTGTGGTC +CAATAGAAAATCAAGCAAGCCACATATGTAATTTTAGATGCTTTTGCTTTCCACATTAAA +AAAGTAAAAAGAAATAAGATAAATTAATTTTAATAACTATTATATTTAGCTCAAATTATA +TAAGATACTATTATTTCAACATATAACTAATATCAAAATTATTAAGGCTATATTTTTCGT +GTTTTTTTATTGTCTTTGAAGTCAGATGTGCATTTTATACTTGCAGAAAATGTCAGTTAG +GGCTGCCCATATTGTAAGGCTTAATAGCCACATGTGTCTACCATATTGGACAGCACAGCC +CTAGAGTTATTTTTGCTTGCTTTTCACTTGAAACAAATGTCAGCATGCAGGAAACATCTA +AAGCCAATTTCTATAGAAAACTGTATATTATTTGTATAATATAGTAGTAATAGCAACTTT +TATATTCTATAAAATAAATTCTTCATGATGAATTCTATAATAATAACTGTGTAGATCCAA +TTTCTATACAATATTATAGAATGTTCTATCTGTTACTTATGGAATACATAGTTATCTGGC +AGCCACACTTCTAAGTAATATAACTCCAAAGTGAAATGCCATGGGCAGCAATGAGCTCTG +GCAATAGGTTGAAATTTTGGCATTGAGCAGGCCAAGGTTAGAATGGAATCCAAGAACTGG +GAACTGAGGTCTCCAGCCTTGCTGGAGAGGAACACTGAAAGACAGTCAAATAGTCAGAAG +TCAGGCCTCACACCTGTATATAAGGTCTAGATAAAGCCATGGTTTAAAAGTCTTGCATGC +TGTTGTTTTCCAGAAAGTGCTAGTCCTTAGTGCCTGGGAGAGTTGGTGGATCCCAGCAAC +CATGTGAAGTGTCAGGGCTCAGAGTGAAGCTATCAATCATGGCACAGCTAGACCTCAAGG +CCTAGAGCAGGCCAACAGTCAGGAGAAGAGGAGAATAGGCAGAGGAAAAATCAAAACCAG +CACCAAGACTCAAGGCATAAAGAATAAGGAGACTTTGTAATTAAGACACACTTCTCAAAG +AGAAGATCTCATATAAAGCTCCTGAGGAAGCAGGACCTAAAGAATGGGTTGCTGGAGTGT +ACTCAGGGTAAGACTTGGGAGAGGAAAATAAGTCAATCCTGCTTTGGGAAAATGCATCTC +AAAAAGGACCTAACCCAATTTTTCTATATTCATTATTGGAGTATTATAAAAAATATGGTG +TTGCCACCAACTTTTCCCTTCTGGAATCAAAAGACTGAATTTAAGCCTTACCCTGCCACA +TACAAATCATAAAACCCTCTGTGCCTCAGTTCCAGAACCTCACATACTTGTTAGGTGGAT +CACTGAGATGATGAGAGGACATGCATTTATTCTTTTGAGTATGTATTGAGTACCTACCGT +GACTTAGGCACTGGGCTAATGGTAGGGCACAGAAGGATGAAAAGAGAGAGCTACTGTGGA +CATGTGGACATGGAGTTCACATCCGAATGAGAGGCCCAACAATTACGATAGAAGGTAATC +AGAGCTCAATAAGAGGAATGTACATGTTATTTGTTAGTGAAGCCCAACATGGGGAGTAAG +TCTTCCCAGAAAAGTGACATGTAGTTAAGCACTAAAGGATCAGTGGAGCTTTCCAGGATA +GGAATCTTGGGTAAACGTGATTGAGCTAACACACTGTGTTCCAGAACTTGCGTGTGTGTG +TGTGTGTGTGTGTGTGTGTGAGCATGCACATGTGTTGGGAGTAAGGGAAGATGTTAAACA +GCATCCAGGGACTAGATTATGTGGTTTCATGAATCCCAAGCTAAGACATTTTATGTTGTC +AGGGAGGAAAATCGGAATCATCATCTGGAGAAGATATGTGATCCATCATATGGTTTTAAG +CAGAGACATGAAAGGAACAGATTTGTTTTTAAAAAGATTATTCTAGCTACTAAGTAAAGA +AAAGAATGGAATGGGTTGAAATTAGATTTGATATATAAATTTAACATCGTCCAAACACAC +CTTTGGGAACATAGGAGATTTTTCTCACTCTGAAATCTTTGTTCCTTCTCTTAGACCCAC +CCACATAGGGCTGGTATTCTATGTTAAAATATAGAAATTCTTCTGTCAGTTAGTAAATGG +CTACTTCACCAAGATCCTGAAGTGCCTTCCCCTGGGATCTCTTGGGCTGTCACCAAGGAT +CAGCAATAACGGGGTAACACGTGTCACAGTAGCATGCCACTAGCACCTGCTCCAGGATTA +TAGTTGATGTGCATTCTGATTAGTTGGTGCTGGAAGGTTGATAATTTTTTTTTTTCATTT +TGCTCCTGTCCTCACACACATGAATGCACTCAAAAATGCCCCTTGAGTGCATCCTTGTCT +TCCTTTCCCCTCTTCCACTGCTCACCCTGACTTCCACTTGCCCTGAGTGGAACCCATCCT +TGGATTTGGCCACAGTATTAGTAGAAGAGCTATTAACCTGGCAACACAAAATCAATGCCA +AGCAGAAAACCAGTGGGAGAGTAGGGCTGACAGTGGTGTTGCAGTGATGAGCTGAGAGTA +AGCAGGCATTTAGGTAGGCACTGCCAGGGAGGCAGTAGGAGATATCAGGAAGAGTCCAAG +GGATCCAGGCCCAAGGTTCCAGTCCTCCCAGAGGATTGTCAAAAGGAGCCATGTGGAATT +GTGGTCCAAAAGGACTTGGGTTTGGGAACAGAAGATTTAAAAAAGGGATTCAGTAACTGA +CAGTGTTGCCTATATTCTGTGAATAGAAACAGTGAATATGCTCTTTGAGTAGACTCTGGA +TTCGTAGAGACCAGGGTCTGAATCCCTTCTCCACTTCTTATGACCTGCAAGACTAAGAGG +AAATTACTTGGCCCGTCTAAGCCTGGTGTTTCATCTAAAATGGGGTAATAATATGACCTA +CCATATATAGTAATTGTGAAGGTTCAAATAAAATAATGAATGTGGACCTCGTAGTACATA +GTAAGTGCTCAATTATTATTACTACTTCCAAGCACATGTTGATATGCCATAGAACTAAGC +AAGAATCCATGTTCAAAAGCTTTCGTGCAATGTTACTGTAGAACTTGTTGGGCCACTATT +GAGGAATCAAACTGTTGACCTGGGGGCTTCTAAAAAGCCTCCTGGTTAGAGACAAGACGG +ATTCAAGAAAGTGAAGCAAAGCTGACCCCAAAGCAATTATGGGGTTTGAGCTGGGGACAT +TTTAAAAACTCCAGGCTCATCAGCAAACTTTCTGCTTGAGAGGCCACCAATTATGTACTG +TGTAAATGTAGGCAAGTCTTTCTGAATTAAAAGGTGAAACACTTCTAAACCACTAGAATG +AATGGTCTTTAGACAGCATAGAACAAATAACCTAGGAAAGAAAACAGAAATAATAAGATT +TCAAGCAGGCCTGGCAGAATCAAAATTAGTGTTGAGGTTACCCAATAGAAAAATGAGACA +TTGGAAAGAAAGAGAAAAAAAGTTTTAAATGATCCTTTTGAAACCAGAGAAGAGTCAACA +GCTAGGTTCCAGAGAATAAAATTGAGCCTTCTACATAGGAAGCAGCATTCCATGCTTTAT +ATAAAATATGAAGGGTTAACATGTATTGGGAAGTAACTAAATAGTTGTTATCAGCGCCAA +AGTAACTGGACGTAAAGGAGATTTATGACTTTTCAGTTTGGGAGGTAGAAATAGCCACTT +GTAGAACTAATGTGACTGGTGAGGAGATATGTTTGTCTTCCTGGAGGATGTATGTAAGAC +ACATGGGAATATGCTGCAGGGTTTATTAAATCCACCAATTGTTAACTTGTGTGAATACTA +ATGGTACTTTCAGAAGAATTCATAGTCTGCTTATTTAAGTGAAAGTCAAAAGATTTGGTG +ATATCAGTTAAATGTTATGATTTTGGAAGATGCTAGAGCTGTAGGAAATAAAAAGCAAAG +TACACATAGCAAGGGGGAGACAGATCACATCCTTTTCTGAGCGCAAGTGGGAAAGGCTTT +CCATTTTTAAGGAACCATGTGAATAGATTGGGCCCACACATGTAATCTAGGATAATCTCT +CCTTTTCAAGATCTTTAATTTAATCACATCTATAAAGTCTCTTTTGCCAAGTGAGGTAAG +AGGCTCTGGGGATCAGGATGTAGACATCTTTGAGAACACATTATATTGTGCTTATCATAA +TAATAATAAAGAATGTCAAAGTTTCATGTCAGAGATAAATATGCAGGTGTTATGAAGACA +GAATGCAACTCATGCTGGGGAAAAAGATATGCAATGATAAAACATATTCAAAAGAAATAT +TTAAAAGGATTCGAGAGGAGTAATGTATGTCAAGCAGGTATAGATGTGCATTGTGCATTA +CAGGGTAGAGATAGTGAAATATGTTTCAATCAAGACCACAGACTGTATAAGAAAGGTATT +GTGAGAGCATATTGTAGACCACTAGACCATTTAGAGGATACATTGTTCAGAGGAAAATTG +GAAAATTTAAACATTCTATCTTCCAAAATGGGGGAATTCAAATATCAGGAGTTCTGCTAA +AAGATTTGTTCTGGTAAAATAGTTTACTTGCATTAATGAGAATTTCTTTACCCAAAAGAG +TGGAAGAAGCAGTCTGAGGAGCTACCACTTATTGGTACCATGGAGAAGGCATTGTCACAT +AAGGGAGCAAACACTATTAAAAATCTAAGAGGTATTGTTCCAAACATTAAGAAAAATTCA +AAATATTCCTGGGGGAAAAAGGTAGGATGTTAGACCTTTTTAAAAATGGGTGTTCACATA +TGCACATACACATACAATCACTTTTATTAAAAATAAAAGCATAAATTGTTCCCAATAGAC +TACCTATAAAAAAAAGAGAGACCTCTACATTAACCAACTTGACTATCAAACGCTCTTTCT +TCTGAGGTTTTGATGAACATTATTTCAGTCCCTACACTGTGTTGCAAATTTAGGCTAAAT +AATTTGCAAAAATGCAGATGGTATAAGGCTGTGCTGACATAGTTCAAATGACAAAAATGT +AAAGATATTAGCTTACATTAAAGCTCAATTTTAGACAGTATATTATATAAGTGGCAAAGG +AACTAACAATTTCAGGCTGAACAAAGATCAAAGGAGGTTATAGTCCCACTAAAACATGTC +CTGAGCAGCCCACATCAAGGGGCCAGTTCTTGGAAAGAGCATTCTAGCATTGCAGACAGT +GATGTAAGAGAGTCCCTTCTTTGATGAAAGTTTTTTCATATGAAGCAGCTTGATAACATA +TGTTACAGATGTCAGCCAGTGTTTGGAGGGCTAACAAGTAGACATGGTTCAGGAAGATAG +AACAGGGACCATGAATAATGGAGATGGGTTTCAATTTAGCATTTTCCAACAGTTACGCTT +TCTAGGTGTCTGAGAATATAGTAGGTGCATTGAGTAATGACAACTTCCCCAGACTCTGGA +GAAGTTCCAATAGAAGCTGAACAGGCTCCTATCAGTGACGCTTTCTGGAGAGTTTTGGCT +TAAACGAGAAATTGAGTGAAAACTCTTTAGGGCCTCTTCAACTTCCCAGCTTTAACGTCA +GACCACACTCATGCAGCAGAGGGGAGGCATCGTGAAGTTGCCCACCTCAGTTTATAGTAA +GAACCACAGTTTGATCACTTGGCTGTCCTCTACACTCTAATCTTTCTTTACCCACAGACC +TCAGACTCTCATACTTCCCACTAACCGTGTTCTCAGTCCTCACTTCTGGTTTCCAAAAGT +CAGAAACTAGAGACTTAAATAACTCCTTTTATTCTAGGGATTAATTGGTTCCTATCAAAC +TCTTCTATTACTATAGTTCAGGAGGTTTTCTTTTTTTCTTTTTGGAGGGGATAGGGGATT +AACTACTACAGTCCTGACGAATTGTGATCATGAAGGTATTAAGATGATGCTTCCAATTGC +CTCTGTGAGATGAAGATTATACCTCCCTGGACAAATATCTTGCGCCTAACTTGTAATTTT +TCAATGTTTCTAGTTGCTGTCTCTTCCTATTTGTCGTGTTACATTAAAATGTCCAGTTCA +CATTTCACCAGTTGACCTCACACTTTGAATTCATTGACAGGCAGCATGTCACTTAAACAA +GGATGTGTCTGTGATGCTGCAGAGCATCTGTAGTTGCTAAACATATGATTTCCCTCATTT +GGCCCTCACATGTCTATCAATCTCTATCACTACAAGTTGGTCTCATCAATAAAATGAATG +GCATCACTGAATCCAAGTTTTTAATTTCCTTAGTATCATTAGTTTCCAATAGCACCTTGA +ACACAGCATCATTTCCCTTGCTACATACATAAGGGTGATGAAAAATAAATAGAGAGAGGC +ACTTGATGTTACTGTGGTACGACTCCTAAGGGTGGGAAGGAAGTGCTCTTTAAACAGAAC +CAGTAGGAGCCTCCCAGAGGCAATTTAAAAAGGAAAATATTAGGAAGACAGGAAATAGAA +AGTGGCAATTTGTAGGCATTACAAATAAGCTGGTAGTACTCCTGGGGGCAAAAAGGATCG +TTTTGTCTGCTAGATGAGCAAACCCCAGGGTTGCCCCCAGTTGTGAAGTATCTCTTGATT +CAGCAGGAAGATGCCACACCACTCAGTCTTGCTAATAGCCATTGCATTCCAGATGCAGCT +CTTATTTTCCCTTGATTCTTAATGTAAAAAGCCCATAGACCTCTAAAACATCAGGGACCT +GATGCTACCTCTGAGCATGCAGAGTCAGGGCTTATGCTGTGGAAAGGACTTTAACTCTTC +ACACACTAAGGGCTCCATTCAGAGCAACCACAAAAGGGATACACTGATGGAGCTGGCTTG +AAAGCAGTGAGTTGTTCTGAATGTACTCCACAGTAGCATCATATCCTAAATACATTCAAA +ACCCACAGCTCCTGAATTGCTGAAGCTTAGCCTAGGGCAAATGCAGACAGTGGACATACC +AGACGGCAATTCCAGGCACCCACTGGCATTCTGAGGCTTGCCTACTATTTAGCCATCCTG +TGCTCAGCTCAGAGAGGGGCCTCCACTTTGACCTGGATGGCAACTTTTCATATTTACTTG +ACAATCCATGTTAATTTCCCCCTTTATTTAAAGAGAATATTGAGAAGGACATGTATGCTC +AAACTCCACAATTTCACACCGCAGAACCACTGAAGCTTAACAGTGAAAGGTGTATGAAAT +GCTGGTGCTCATGGAAAAATGCAGGCACAGTTTTATCTGCTAGCAGCCGAGAATCAAAGC +AACAGCCTGATCCTACCTGATAATAAGATGATAAGAAGGCCAAGTGGTAATACAATATGT +GAAGCTCTTTTCTTACGTAAGTACATAAGTGGAGTTTCACCTTGGGCCATTCTTTACACA +CTAATGAGTGTATGTGTGAGTGTGTATGTAAGAAAAAATTTCAAAATTTTCTAAAGCTAC +ATATATAAAGATAATGTCTAAATGTGAAAATCAGCCCAATTGCAAAAGGGCCATCCTACT +TGAAACTTGCAGAATAAATATTTCAGTTAAGCAAGGGCAAGTTCTCAGCCCCCAGCGGAA +CAGAATTCTGGGGAAGAGGAGTCACAGATAGACTATGATGAGAGGGTTCTTGAAAACTAA +ATTGTAGGAGTCAACACAGTGAGGTGAAAGGAAGCCTTAGATTTGGAGTCGGGGTCTTGT +TCTAGGTGTAACTCCACCACCTCTCCAAAGAATGTTTGCTCAATCATCAGCCTTTGAATT +TCCTTCTGTGAAATCCTAGAGAGGGCTTGGATATTCCAAGGTTCCTTCTTGGTCTGAAAT +TCTGTGATCCTGAAATCTTACAAATGGTCCCATCAGTTTACATATGGACTTATTTCTAGT +AAAGAATTATTATTATTTTAAAATAATAAAAAGTGTTACTTACTGAGCCCTTTGTATGTG +TCGGGAACATGTATGCATTATCTCATTCCACAGGAGAAGATTATTTTCCTTATTTTATAG +ATGACAAAACTGAGATTTAAAGAGGATAATTCCACCAACTCAAATACCTGTTAAGTAGCA +CACCAGTTATTAGTGAATATTTATTGTTAATCAAATGGCATTTTATAGGATTTTGTCACT +TTTACTTTGCAGATGGAGACAGAAGCTTTGATAATTTATTCCAGGGGTCAGCAAATTCTT +TCTGTAATGGGCCAGATGGCAACAATTTTAGGCTCTGTAGGCCATACAGTCTCTGTCACA +GCTACTCAACCCTGCTATTGTACTGCCATAGACAACGCTTAAATGAAAGAGTGTAGCTGT +GTTCCGGTAAAACTTTTTTTATGGATGCTGAAATTTGAATTTCATGTAATTTTCATGTGC +CAAGAAATATTCTTCTTTTGATTTTGTTTCAATCATTTAAAAAAGGTAAAAACCATTCTT +AGTTCATAGGCCATTGTAAACAGGAAGCAGGCTGGATTTGGCTTGCAGATCATAGTTTGA +TTTATTCCAAACTCAAACAGCAATTCAAGATGAAGAAACAGAGGACCAGTTAAATAAAGA +ATGTGAAGCAGAAGGCAGGAAAGAACATAAGAAAAACATACATTTCATTAAAATGTGTCC +TCTGTCTTGACATGGGTATCACAGGGAGTTGAACTAACTGGTTCTTATTTACAAGGCCCC +AACTGTTCTTAAGAAAAATGTTAGGGTTCCCAGAAACATAAGGGCTTTGACCATATCATT +TCCAGGACAAGATCACAGACATAATCAGTGCCGTCTGTTTAAAGGCTTTAAGAGCCAGCT +GAGCCAATTTAGCATCAATTTAGTACAATCAGCAACTAATGAAAGAGAAGTCAGGGTGGC +CATAAAATGATCAGGATTGCTCATGTTGGTGTAAGGGATCATTCAGTTGTATTCTGCAGG +AACAACCCGTCATCTTGAATATCAGCAAAAAGCTCTATTTAGAGACAATTACAGTAATAA +TATCAGGTTATAATACCATGTTCACAGGGAAAAAATACATACAGAACGTGTTCAGAATGT +AGGTTTTTACCATTGCCTTTTAATATCAGAGACAATTCTTCTGAACACAGTCCATGACAG +TGCTGTGAATGTGAACCCCTGCATTTCTGCCCAGCTCTCTTTTCAGTGTGATTGAGCCCA +TTGAACCCAAGAGATTCTGGATTACCCACAGGAATAATGTTATAACCCATCACTGTTAAA +ATGCATATATGTTTTTCATCCCATCTTTACAAAGTTTTCTGTTTACAGCCTTCAGTTATC +CATTGCTACAAGGAGGGGAGAAAAGGCCTTCATAAATACCATAAATACAGAGTGATTGAT +TGTCTTGATGTAAATTCCAATATAGGCACATACTGTATGCTCATGGAAATTTAGACTTAC +GCACAGTTCATCTGCTCTGCCTCCGCCTTAATCTTTGACTGGTTAGCAGTCAAGATCATC +CAGACACTGCTGGATGCTCATTTTTAAACAGAAACAATTGCTAAGATATATTTTTAACAA +TATTCTTTCCCTTATTCTGCAAAAGCATAGGATTAACATTACATATTACAGATATTTTTT +TCTAAACTACAACTCTTTTGGGGAAATGGGCATATGTCTCAGAGATAAAACACTATAAAA +ATGATGAAATATTGATTTTATTTTTAAGACATACATTTAGGCCTCTTTTTAATTAGTATT +GTTGACCCAATGGACTTAGCCTATGTGTTAACCCATATTCTTTATCATGAAAATCAATAA +TATGGACAACTACTATGTTCCCACAGATGTTGAATGCAAAAAGACAAAGTTAGGGAGTTT +ACAGAAGAGCTTGTTATCAGGATAACTTGACAATTTATTAGTGATGCAATGTCAGAGGCC +ACCATCACTGCATTCTCTATGGTGTTGCTGGTTCACCAGATGGAAGTTATTTGGGCGTAC +TAGTAAGTCTTTCCTGAAATATTACACCCTTGTTCTTTCTAATTAAATGAAAAATTAAAG +TTGCTGATTTTGCAACAAGGATGCTAAACTACATACAGACATGATGTATGAATTCCATAT +AGTTAAATCAGGCCTCGAAATTTCTGAAGTAACAATTTTAATAAAGACTGTCCAGGGTCT +AGGCATGGAGGAGTTTGTGCTTCACTTGATAGAAACATCTAATAAAACATGGTTCAATCA +ACTATGTTCAATACGTCCTTTCAAATACAGCAAATGAGATGAGATCATACTCTACTCTAC +AGAAAACTATGCCTTCGTTTCATCTTTGGTTACTGAATTTAATTTAGCCAAGGTGACAGA +AGGAGCTTCTTAACAGAGCCTTGCTAAACCTTTTAAATTATCCTTCCTAGCAAACTGGCC +TGGCTATCACATTGCCCAAAGCATTCACCTTTTATTCAATCACACATTCACTTATATTTT +CATTCATTAATTCACAAATCATTTATTTAACAAATATTGAAGTCCCAGTATGTGCCAGAC +ATTGTGCTAAGTTTTGGCACTAGAAGATAAATGGGATTCCTGCCATCCAAGGGCCACGGT +TCAAGAGGGGTCTCCAGTCTAACAGTACCTTCCTCTTGTCAAAATCTGAGACGATTGACT +TCCAGTACCACTTTTCTAGCTTGCTTTTCTGATCATAGTTATCTCTGACTTATAACCATA +GAATTTGATATCTGAGCAGGAACCTTAACAATGTTCTGGTTTAGCCACTCATTTAAGTCA +TAAATCAGCTCTCCTTATTAATATGTAGTAGTAATGACAATGGACACTATTAATTATATG +CTTGTCATGTACCAGGCACTATGCCAAGCCATTTATAGTCTTGCCAATTATAAACCCCAT +TGGCAGTTATCCCCATTTAACAGATGATGAATGGACTGAGGCCCAGAGAGGCTTAAGTAA +TCTGCACAAAGTTGTATAGATCCTTGCAACTTAAAAGTGTGATCCCTCAATGGGTATGAT +CAGCATCACTTGGGAATTTGTTGGAAATGCAGAATCATAGACCCACCTGCAGACTTACTG +ATCTGCATTTTAATAAGATCTCCAGGTGATTCATATGCACAGTGAAGTTTGAGAAGCAGA +GGACTGGATAACAAATGAAGGTTTTAACTAGGATAAACTGACTCAAGCCCAAGAAGTTTT +GTTGTTGCTTTTTATCACTTTGTGTTTATAAAATAATGGTGGCTGGGAAGTCAAGGGCAT +ACATACACCTTGGAACATTTTATATAAGGGGCAGGAACTCAAATAGTATCTCACGCCATC +AATTTTTATGTATTCTACGAATCCAAATCATATTAAAATAAGAAAAACCATGAAAACTTA +AACAAGTAGCCTATTTGTTTTCTTTCATCCCTACAATTTAAAAGTGGTTAATATTTGATA +GGTTAATAATAAATATTTTAATATAGTATATTGCATTTGGTTATGAATATATCAAAAGGA +AATACAAAGTGAGCTCCAAAAGATAAACTTCTATTGGGCACATGAAAGAGAACATAAAAT +TTGATGGCAATTACCATTTAATCTATTCATGTTTGGAAACATATTGAAAGAGAAACTCAT +AACTCAGTTAATTGTTATGAATTATTAATTGCTTATTTGAAAAGAGATGAGCAGAACTGT +ACTTGTTGAAAAACTTTCTTTCTCAGTGGCTAACCTTTGTGTCATTGGTTTTATGAGAAC +AAAACGGAAAGAATGACAGCAAGATCCTAATCATCCAAAACTAGAAAGTGACAAGACAGG +GGACATCTCGGTGACTATATAAAGGTTAATTGAGATTGAAATGAAATAGTAATCGCTGGC +CCCACTCCAACCTTCTTAAGTGTGATTCTCTGGGGGTGGGCTCCAGGCATCTGTATTTTA +CAAAACTCCCTAGGTGAGGATAACATGCAGCCAGGATTGAGGACTACATATTTAGCAATT +ATACATTTTCGGAGAGATTTAATCCAGCCGTGAATTGACTCAGGATATTCAGAACCCCAA +GTGAGATGCAAGCTGGCCTCCAGTTTGCCACTCCTAGTTAGACTTCAAGGTAACTAATGC +CAAGAGCACTGCGGACTGTGGGAAGCTTTATAAAGACATGTTCCCTAGATGGTCAGTGAT +TTCTGATCCCAACAGGCTAAGACCAAGAATATGTCTGGATTTAAAAATACCTGACTTAAA +GAGTCCTTGCTTTTTTCCTCAAAAATCAATGTTATGAGCTTCTTCTGCTGGATTAAAAAA +AAAAAAACCTTCAAAAAGTGGAAGCTTTTTCTATTAACTAAATCCAGGGATTTATTGTTT +AGTGTCAGCAGCGTAACTGCTTTATAATTGATTTTTCTGAAAAGAACTGAAAACTTAAGC +TACCTTAATTTCCTTTATCTTGACACACATGATTAGCATTGCACTGAAATATATTTTACC +AGGTTCCCAATTACCATTTTTTAAAACCAACTTCCTCATTGCATACTTGTCTTGATAAAA +TATTTCTAGACAGGTAGAAAGCAAGTAGGTATAAAGAAAAATGTATGACTGCTTTATTCC +TACTGATAGGTTTATCCTGTTTCTTCAAGAATTCCTGTTTATGTTCAGTTATGTTTTTAA +AAGTGAATAGAACTAGAAAAATATATTAACACCTGTTAATTTTTAAAGTCTTGGGATAAA +GAAGCAAGAACATTTTGGACAACGACAGAATTTTAAAGATAATGAAACCAAATGTAATAT +TTGCAACCTAAGCTAATGTGCCTAAATTCTTATAGAATTAGAAACAGCTAGCAGTATATG +TCTGTTATTGTTGCACAGACAAATATTTAGTGTTGAAAAATGCAGCCTCAGCCTCAGTTT +GTGCATGTAAAATGAAGATAAGAATTGGACCCACATCACTATCCATGAGAATTAAATAAC +ACAATGAATTAAAATGTTTAACCCAGTTTCTGTCAGAGTATGGGCACGCAGTAAGATAAT +AAAACTATAAATGATGGTACCCATCCTCAGAGTTTCATTGAAAATGGTGAGGAATGGATT +AACAAATTTAAGAAATCAATTTACAAACAAATGACATAATAAAACGAAAGCTATGATAAT +CATGGCTCCTTCCCGGAAAAAAAAAGAAGGCTACAAAATTATGGGATTTAATACCTATTA +TGTCTTTTTCTGTGGTCGTTTCAAATACTAATTACCATCTGTAAACGTGAATTTTAAGTT +AAGATTTTGTCCAAAATCAATGCCATTTAGTCTTACAGGTTCCAAATAGCAAAATAAAGC +AACCTCTGATAAGTTGTATTCATTAAATTCATCCCAACCTTAGCAGCAATTCTTCATCAA +TTTTAGGATCATCCTAAATCCTGGAAATTACCCTGTAATGCTAAAATACCTGCCTACTGG +AAGGGTCTTGAATTATGGTGACCTCTAAACAGACCAAAAACTAAGTGGGGTTCTCTACCT +GGGCAGAAACCAGTTATCCAGGAGTGATTACTGGGCAGTCACAATTCATAGAGTCACCAT +CAGACCTACTGGATACTTAACTATTATCAGCTTGGTGACTGTTAATACCCTTAGGGGTTT +GTATGTCTGAAACAAGCATTCAGTTCCTCAATTCTCAATTCCCTTTTTTCTTTCTTTCTT +TCTTTTTTTTTTTTTTTTAGAACTCCTCAGGGGACTTTCCACGGGGTTATTTGGCTATTC +TTAGCAAGTTCATGCTATGTGCTATTTTTCAGCAAAGTTAAGGTTTCTCTTTTTATGCTA +GAAAGACTAACATTGAGACTCTAACTTTGAAGAGAATAAGGTTGTTTATTCCTGTAAAAA +GATTTTTTAAAAATAGTATGATTAACAATTTCACCACATGTCACACTGCCCTTGAAAAAG +TAAGGCTGAATTTTCCTAGTAAACTAAAAGGCACTGAGGAACAGAGGATGAGTTAATACT +TCTGCAGCCCTAACACGGTTAACCAAAAATGTAAAAATGAGAAGGAAACATAACCTCCAC +AGAGTAAAGAGACTGTAAGTGTGACTGTCATCGGCAGCACACTGCATGGACTCATTGTCA +GGGGTCAGCCATCTTGGTTTCGTCTGCATTTGTAAAGTGCTGTCCTCCTACACACTATAT +CAGTGTATTATTTTATGTTTTGACATGAATGTATTAGTCGTTGCAGCTAGATGTTGAGTG +AAGAACCCCCAGGAGAGAGAGAAACAGTGTAAGAATACCACTCTGAAGGAGTATGGTAGG +AAGAGAGACCTTGGTTTGAGAGGTTCATTAATCAGCAACCAAACATTTATTGACTGTTTG +AATCCTGCAACATCATAGGTACCATATAAGATAGAAAACAAGTTTAACACAGCCCATGCC +TTAAGGATGTTGCTAAACTTGAGATTGTAGTAAAACGTGAAATCGTAGAGTGAAACCAAA +GTTTCCTGTCCAGAGTACTTAGAGAACTCCTAATGGCTCTGGTTGTGAAAGGAAACTGAA +AACTCTAAGGTCTATTCCAGCTCAGTAGCTGTCTCTTATGTAGTGGTTTGAATCCTGGCT +CTGCCACTTACTAAGTGTGTCTTGTTGAAAAAATTATATAACTTCTCTGACCTAAGATTT +CACTTCTCTAAAAAAATATTATTACACCTCATTGGGGTTGTTATGGAATTAAATGAAATG +CTTGTAAACTACTAAGCACAACATCTGCAGTAAAATAACCTCCATAAATTACAGCTATTA +TTGGTATTACTGTACTATAATCAAGTGGTGGTAGATAACCTTGATGAAGTGCTGGGAAGG +ATTTTCATCTGTCAATGAGCCACTAAACCTGTAAATGGAAATTCTGATCATAAATTTGGG +TTTTTACAGAGTATTTGACAAAGCAGTAAATTATGTGTGTCTATCAAGGAAACATGGGAA +GTCTTGGATGGTGGACAGTACACTTACTATGGATTCCTTAAAACTCTGAAATTCAGTGGC +ACTATGGTATAAATAGAGCTTGAGTTTGTCCCCACAGAAACTTGTATTGAAATTTGATCC +CCACTGTGGTAGTATTGGGAAGTGGGGCCTACAGGGAGGTGTTTGGGTCATGGGGGTAGA +TCCCTCATGAATGGCTACTAGTGCATTCTAGTGGTAGTGAGTGAGTCCTCCTTCTGGTGA +GACTGGATTAATTCTCATGGGAATGGATTAGTTCCCTTGATAATGGGTTGGTATAAAGGC +AGGATGCCCCTTGGGTTTTCTTTCTTTCCAAGTGTCTGCTTCCCCTTTGACCTTCTCTGC +CATGATACAATGAAGCAGGAATACCTTTTCCAGAAACCAGCATCATGCCCTTGAACTTCC +CAGCCTGGAGAACCATAAGCTAAATAAAATTCTTTTCTTTATAAATCACCCAGTCTCAGG +TATTCTGCTATAGCAACGCAAAATGGACTAAAACAAATGGGGAGTAGAAGTATAAAGAAT +TGAAAGTCCATCCTTTACTGAGGAGGTACGTGACAATCCCTGGTCTCATTCCTTGGCCCT +AAGGAGGTAACTAACTTCTAGAGAGTGCCTGAGGCCCCCAGCATTGCTCAGGATTCCCTC +TGAGTATGCTGAGGCAGAGTATGGATCTTCCATTCACTGTGGCTTACTTTCCTGAATGTT +CAGTGACACTGAGACTGTTCGGTGTCTCAACAGTGGTCAGCATTAATCCTTTGTTTTAGT +GAAAGAAAGAATTTTCTCTTGTGTCTGACTTCAAATTAGAATTTTATTTTTTTTGTAAAG +CAGCACAGTAAACTTCAAGTTTGTTAATAAATGTGGAGGCAAAGGAAGTCTTATACTTCT +TTTTCATCAAGAAGGCAAAGCACCACCTATTCCTAGCTCCAACTTTAACACTAGTACAGA +AAATAATGTTCCTCTAGGATATGGATTTTCATCTAAAACTTCATCCAGAAACTGACAGTC +AAAAAGGACACTACAAACGCATTTCATTTTAAGAGAAGACAGTAGTTCACTGGGGATCTT +TTCTTTCCCTCAGCAGGTATCTAGTTTCCAGCTACAAGAGTGTGCATTACTTACTGAAGA +GTGTGTTTGAAAATATGAATAGAGATCATGACCAAAGCCTCCCAGGGGGTTTCTTCGGTC +CAGCATAAGCCTGGATTTCTTCTACAATGTACTTAAGATTTTCCTGCTGACTACGTCTTT +CTTTTCAAACTGCCATGACTTTAATAAAGAGGAAAGTGGATGCCATGTAGGGAAGTGGGC +TAGACTCTTACACATAAAAACTCTCATGTTGTAACCACTTTATAAATTAAACTAAATTTA +AAATTATTTCAGTAATAAACACACTTTGTGCCATCAGTATGCTTGGACATTTCACACATG +TTACTTTATTTATTCTTCCAATAACCCTGCAAAGGAGTGCTAATATACTCATTTTAGAGA +TGAGGAAACTGAGTCTCAGAGAACTTAATATGCTCAAAGCAAACAACTAGTAGCTGATAG +AGCTATTATAAAATCAAAATACAGATTTGACTCCTTGCCCCACATGCCACACCAACTCAC +TGTGATAGGTCCAAAATAAACCCACCTCAAGCCCAACCCTCCTTTAGAACCAGGAGGGTA +ATAGGAACTTGCAGTGTTCTAATATTGGACCACAGCCCAGCTACAGGATCAGTTTGCTTT +CAGTGAAATGAAAACAGCCCTCAGTACTCATTAATGGGAGTGTTGGTAAACACAAACAAT +ACCACACAACAGAGAAAGAGACTTTAGGATAAAAGCAAGCAGTGACTGACAAGGCTTACC +AATTCTCTCTCACTATCTGTTTATCATTTATCAGGAACAAATGTTTGTTCACTGCCCTCT +GTGTGCAGTGAATTTATTTCTCAGAATCAACAACTATTGCACCCATGCATACTTTGCACA +AGCAAGTTATACTCAGATTACCAGCTCACAAGGACAGTGTTTACTTGCATGCAGAGGAGA +GACCCTGCCGTAAAGTAGACACTGCTGAGACATAGTCCCTACCCATTCTCATAGGCCTAA +GATGTTAACGGAAACAACGGGCTTTCATTCCAAGGATGCAAATGATGCAATTCAAGCCAA +ATATCCTGTGTCTTTTTACCAAAAAAAAAAAATCACTCTGACCAATTCCTCAAACCTGTC +AAAAATTTAGATAAATAAACATCAAACTGTGGCCCAATAAGCAGACCCCATGTCACTTCA +CTAATTAATACCCAAAGGAGGAAATAGCATGCATAAATAGCTATCATCTATTTAGTCACT +GGATCATATATGAAAAAGAGGTAACCTTATTCCAACATCATCATCATGGCAGGCTCTTCG +CATCATTTTATCTGATCTTTGCAATATCCCTATAATAGAAGATACCATTTTTTGCTTCTT +ACAGATAAGGAAACCAAGCTTACAGAGGTGAAGCACATTTGAGGTCAGGAATTTAGAAGA +GAAATGAATGAGGCTCAAACCCAGCTCTCTTCCTCTCCACCCCACACCAACATACATTCA +TCGTTCAGGTGCTACGTGTGAGCACAGTGCTGTGCCAACTCTGTGGTAAGCCTTGTAGGG +AAGCAGAGGCAAGAATGAGGAAGACTCTTGAACATTAGTCACTCACATGGTGACTATTTT +TTTTTTTTTTTTCTGAGACTGAGATTTGCTTTTGTCGCCCAGGCTGGAGTGCAATGGGGC +GATCTCAGCTCATTACAACCTCCACCTCCCAGGTTCAAGTGATTCTCCTGCCTCAGCCTC +CCAAGTAGCTGGGATTACAGGCATGTGCCACCATGCCCGGCTAATTTTTGTATTTTTAGT +GGAGACGGGGTTTCACCATGTTGGTCAGGCTGGTGTCGAACTCCTGACCTCCAGTGATCT +TCCCGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCACGCCCAGCCCAT +GGTGACTTTAAAAAGCAATAAAAAGTCATTATGCACAGTGTTGTCCAGTAGCCTAATGTG +GTGCTCAGGATCAAGTGAACCTGAGGGTTGGATGCTGGAAGCAGGAAGGTGCCCATCTTT +TCCAAAGCAGCAGGCTTGTTCTTCTTCAACAGCTGTGTTAGTGTGCGTAAAAAGTAATAA +ATGCCTGACTCGCTCTGAGAGCCCAATATTCTCAGACAGGCAGGGCAACCACAAAGTGAC +TCTACTCCACAGCTCTGTGGTGAGATGGAAGGTAACTGCTGTTGCACTGCAGCCATTTCT +GTGAAATGAGGTGACAGCACTGGAGAGCATGACAAGAACAATACGCGGATGAGCCTTTTA +CTGTGGTAGCAACTTTCATGCTGTCGTGTCAGTGCTACATGGTCAGGCTGCCTCTGTTGC +CCCGGAGACAGGAATGGTAAGAATTCTCTTCATCATCAAATCATTAGCTGCCAGTAGCAG +ACACCCTGTCTCAGCTCCATGTCCTGTGCCTGTCATTCCTTCTAAAATGGTGTATGAGGA +AAAGTAGAGATAGCTCAATATAGTGATTGCACATCCTAAAAACAGGATCTTTGAAAACAT +GGAGAGGTGCCACGAAATAATCCCTGAAGAGGTTTGAAAGGATGCACCCATTTCGAGAAG +GGATAGAACGATTCCCCAGGTCATAACACAGTGTCCTATGATGATGGGAGGCAGGTCATT +TCATCTTAGAAACAGAAAACCATTACATGCCAAGAGGGATGAGCAATGAAAGACAAAGGC +CGTGAAGGAGCAGTGAAAAGCATCCTGGAATCACTTGGGGCTTTAAATTGCATGGATGGA +TCTTTTTAAAGTGAGTAGTAAGATAATAAAGTGATGCATAGGAAGACTTGACACCCTTCA +ACCCTGGTCTGATAAGCCAAAGGCTCACTTGGCTGTGAGCTAGCTGGGTTTAACAAAATG +AAGGCCCTTAGATGCTAAGAAGATGTCTACATTCCTACTTTTAATCTTTTGAAGAGAGAG +TGGGATTTGTACACAGCATGAGCAAGTTCTGTCTCATGCTATCTGATTTTGGAGTCTCTT +GTAGGTCCATGCCTAATCCCAGAGACTGTAGTATTGGAGGATTACTCCCACTCAGATAAA +TCAGCCATGCCTCTCTCAGAGCTCCCACCAGAATCAAGTAGAACCCTTGGTAGGCCTGCT +CGCTTATCAATACTCCTAGCTGGATTTTAGAATAGCCTTTGATGTGGCTGCAGATACCAC +ACTACATCTTATTTAATCCTTGACTCTGAAAGTAGGTTAAAGTATTGGGTAGCAAGTAGG +GAAGTCAGAGCTAGTGTTTCCATTTGGTTTCATGTTTGTCCACAAAGACCTTTGTCTGGC +TATGCAATGCAATATTGTTGCTTATGTAACGTGATGCAAGACCTCAGTCCCCAAGTTGGA +TGACATTTGTGCTTAGAAGGACCATTATTACCAGATACTCTGTCATAAAATCTTTCTCCA +TAAGGCCATACTGGAATGCCAGGTCTTAGGTCCATGGAATTATATATTTGGAGTGTTGTG +TCATATAAATCAATATACTGATGAATTAATAATTCTTCTGCAGAAATGAAGCACAACACC +ATCCACACATGTAAGAAATGGCTTCCTTTTTATTCTATCATGATTATAACCACTAGTACA +ACTAGGTTATATTATCTGAAGAAAATACAAATCTCAAACCTCAGGCTTGCCTGGCCAATG +CAACCTTTTCTGTGCTGCATTAGGTGTAAAAATATACAATTGTCCCAGTCTGTTCTCCTT +CATTAAGAAATCACTCTTGGAGAGAAATAAAAGCCAGTAGACATCATCCAAATACAAAGT +AAACACCATACACCTATCATTCAGCTTATTTTGTAGTATGAATTTCTGGCTCTTTTGGTA +CTAAATCCCCAATCCAATACTTCAGCTTAAAAGAGCAGTACATATTTGGAAAAGTCTAGA +GGCAATGCATTAGAATTCCATTTGCACCTTTTACATTTACCCATGTGCATGGCACTGTGC +TCAGTGCTATAGATATACAGATATGAGCATTCATCCAACACAGTTATGTTGATTGTGTGA +TTATGCTCAATTAATATGGAACTTGGGAATATTGTCTCATATCATGCTAAATTAAAACAT +ATATGTGTCTATCCAATATTCATGTAATGCTCTAAGACAAATAGATTTTTTGGGGGTGGG +ATTGTTTTCCTTTTATTAATGATCTAGAAAATCTTATGCATTTTTTAATAATAATTTATT +TTTTAAGTTTTTTATAACAAGAAAATTGCCACATTCTTTTATAAATATTACAGTTTGAAT +CATACATAAGCCACTGGAATAAATTATTTATGCCAGTAGACTTATGAGTTTGTAGTGTGG +GGATGTGTTTGCCTCCTAATGTATTAGAAAATTATGAATCTAATACTTTGCCGTAACATC +TAAGAAAAAGCACATAAATTTTGGGGGGCTTTTTGTGTTATGAGTACTGTAAGGAAATTT +TTCTGAAGACATTTTTAATTTGTATATCCCAGCTTCCTTAGTTAGAGATATTAGAGAATG +AGCCCGTCCTCAGCATGGTGTGTTTTTAGCCATCATGTTAGAGAAAAAGGCTGTTTCCCA +TTAAAAGTTGCTCTCATTTGCTCTAATAGCCCAAGTGCAGATATATTCAATTCCAACATG +TTCGCATCTAAAAGTTTGGAAGTGTAATTCACCATATGCCTAATGTCAAATATTAAAACA +CACAGAACAATAAAAAGCTGATCCAAAATCCCCTTACTTTAAATCTATTAGTCAGATTAA +TGGGGATGACACATGAGTTCCACTGTTATACTACTCCAGTGGCAATCTTCTAAAATTAGG +AACTGCCAATCCGGGGGAAGCAAAAGAACTCTATATCATTTTAAATTTAACTCCAGCCTA +CTCTGAAGCCATTAGAGGCGATTAAAGGAGATCTCTATCCATTAAATTTAGCCCAGTAAT +CTTAAAGTTCAAAAGGTAAAAAGCACTTTTCACCATAAATAAACTGAGAGGCAAAATTAT +TTTCAATGAAGTTTCAATTTCAGTGAAAATAAAGTAGGTAATTACATTGGCTATTACTAA +GGTCACTGCCTTCATTGACCATCTGGCTTAAAATTAAAAAATAGGTATCATTTGAGACAT +GGACAGAAATGAGCAAAGTGTGCACTGCTTCCTTTTTAAAGTCCTGCAAATTCAGTTAAT +TCACAGATTAACAATATTCATGAAACAATTATTCAAAAATTAACCTGATGGCCTTTTTGA +AGCTGAGCAACTCAGGAAAAGAAGAAGAAAAACATGTAATGTCTTACCATTAATTACCAT +TACCATAATACCATAATTACTGCTTTCCATATGATAGTTCCTTGGCATATCATTTTTGCA +TACAAAAATTGGTAGGCCAAATTTGTCATGCCAATTTCTGTAGATTTTCTGTATCTGGTG +TCCTATTTGCTGGATGTGAACTTCATTTTCAAATTGGAAACATTGTTTTCTTGTAAGGAA +TATAACTTAATGTTTGCCTTGTTTCGTTCTACTTCCTACAATCTCAGAAGGGATCAAAAC +AGTTTAGAAAGTTGAACTTTCTAAATGCTGTTTTAAAGTCATTTTCCATATGTATTGTTT +TTTATTTTATTTTATTTTTATCATTATCTTTTACCACTGAAAAATGGCATTACTGGATTT +TGATATAGCTTAGGTTCACACTATCTATTATTACCTGAAGTATATCAAAGAGGAAAAAGT +TAAATTAGTTCATTGCTTTTCCTCTTTTGTAACTTTGCAAAGACATATATGCATATTGTT +CAAAAAGAGAGAGAGAGAAATTGCCTTTAATTTTATTTGAGTCCTAAACCTAGGATAACT +TTATTCATATATCCTTTGTAAAACTCAGGTTCTGTTGTGTTTTGTTTTGCTTTCCTAACA +TAAAGGCCACTAGCTTCAGGTTATGCTATTCATTCAGCCTGAAAATAGAATACATACTTT +CAGAAGATCCTGTTCTCTGCATTCACAGCTGTTGGAGAGTCTTTGAAAATACCCTTGCCA +GTATACAGAGATGTCAGCCTAAAGAACAGAAAGAGAAGATGGGGGAGGAAAAAAAGGCAG +GGGTAAAAAATAAAAAGTTGCCAAAAGAAAAAAAAATGTATTTTCAATTCAATTTGAGCT +TATTTCTATTCATTCAAGTCATTTGGAATTATTTGCAGTCAAGATTAATGATTCTTTACA +GGTTGGGGGAGGACTTAGCAGCATCACCACTGATTTCTCCTGACAAAATTTATTATGCAT +TGATGCTAGCAGGACACCAGCAGGAGAGAGTTTGTTAAAACACCTTCAGAATAGAGCACT +TTAACCTAGAACGTTGCTCAAACGAGCTGTCCCAATACACGGTTTTGGAATGTTTTAACA +CAAGCATTCATAGCAGCATTTTAAGATGGAGCCAGCCGGGTACTCCTAGGGCAAATTATT +TGCTTGTGGATTTTCCAGTGGGGAAATTTAAATCACAATTCAGTATCCCTCAACTTTCCA +ACTAGTCCCATGTACACTCAGGGAGAGCAAATGAACTTTTGAAGTATAAAAGTACAATTG +TGGCTCTCTTTTTTTTCGCCTAATTTCTCACTTTGTTCTTTTCCTTTTCTTTAAAATATT +AAGATAAGATTAGAAAATAATTTGCTTTGTCAGGAAAGGAAAACCTCTAGAAAACAGTTC +TCAGTGCAACGAGCATGCAAGCTAAGGCCCGTTTCCTCAAGGGCAGAGTTTCAGAGTCAC +AGATGGTTAGTCTGGGTTCTCGTCGTGAGCTTCATGAAACTCAGCTCATGCCCCGGTGCA +ATGCCATCAAACCATGGCCTGCACAGTGCCGAACTGACAGTTCATCATGAGCGCACTCCC +AGGTCTTTAGTAGCCTCATTTACCATGACATCGCTCCTCTGCTCTTACTGTCAGAAAGAG +GTGAGCTCATTTCTCCTCAGCTTTCCTTCTGAGCCCTCACAGATAATATTTTACCAGGCA +GGACAGATTTTACACTTTGGGAAAACTTTGGCAATTAAATCTCACAAAGAAATCCAATAG +TTTTCTATTTAGGAAATGAAATTATTTCCTCTATGGCCCATGGTTTAATATTGACTTCTT +ACGAATATTTATATTCACAGCAACTTGGCTGCACTGCTGGGGAAAAAGGCAGCTCTATGT +GAAATAATAGCTGTAATTATTCGATAGCTTCTTTTTTTTGACAGCAGTACATCCTTCAGC +TTTCACTTTTATACCAAACTGGAAATTAGGAGGTAGCCTAGCTGTGAAAACTGATGCTGG +AAACTGTCCATCCATCATGAGGAATGATCCTTTCTCTGAGGGGAATTTGCTGCTGGATTG +CCAAGTGCATAATATTCCCCTGGAGCAAGGCTGCATAAAACAACACTGCTGTGACACATT +CTGAGATATTTAACTCTAGAGGGTCTGGCAGCCCCGTGTACTGGGCTGCTAATGGTGTTC +AGTAGTTGTCATCGGGTCTTAGAGCCCAGAAGGTCAGAAGAATTTCTCTAATCCTAGGGT +AAGAGACCAATTAAAATCCATCCCAGCCAGGACAGTCTCCACAAAATCCATTATCCCTGG +CCTATTTTTAGGCCCTTAAAGGATGGATGCTGGGTGAAACAAGACAGAGAAGGCTTTAAT +TTATTCAATACATGTGTAAAAAGCGTGAATTCTATACCAGCCACTGCTCTGGATATTGAG +TATACTGTGTTAAGAAGACATACATAGACCCTGCTCTCAAGGAGCTCATACACTGGTGGG +AGGCACATGGAAAACAGGGAAAGAAATAAACAGTGGGCAAAGACCACTGTAGACTGAATA +GTCATTGAAGGTCTTTCTGAGAAGGGAGTACTTCAGCTGAGATCCAAGTATTAAGGAGAC +CCCACCATGGAAAGTTCTGGAGGAAGAGTGTTCCAGGCGGAGGAGACAATTCCTGCAAAA +GCTGAAAGGCAGGAAGGAGCTGGGCCAGTTCAGAAAATGGAAGGAAGCAAGTATGGCTGG +AGGGTGCTGATGAGGGAGAGGTGGTCTGAGATGCGAAGAGGAAGATAAACACCAGATCAC +CCATCCTTGAAGGCCAACACTAGAGATATGGATTCTCTTTTTTTCTTTTTTTTTTCTTTT +TTTTTTCTTTTGAGACGGAGTCTTGCTCTGTCTCCAGGCTGGAGTGGCACAGTCTCGGCT +CACTGCAACCTCTGCCTCCCGGGTTCAAGCGATTCCCCTGCCTCAGCCTCCTGAGTAGCT +GGAACTACAGGTGTGCACCACCATGCCCAGCTAATTTATTGTATTTTAGTAAAGACAGGG +TTTCACCATGTTGGCCAGGATGTTCTTGATCTCTTGACCTCGTGAACTGCCCACCTCAGC +CTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACCGCGCCTGGCCTAGAGACATGGATTC +TATTCCAAGTTCCCTGGGCCTTGAGCAGAGGCGTGCCATGATATAGGAGTTTAAATTAAA +AAATAACTCTGGCTACTGTGTGGACAATGGATTGCAAGCAGGGGCAAGAAGGAAAGGGCA +AGGTTTGTAATTAGCAGGATTACAGTAGACCAGGTAAGGGGTGTTAGTGGCTTGGACCAT +TAGGAGCAACGCAGATAATGAAAATAGATGGATTTGGGATCTGTCGTAGTCTCTGCCTGC +CTTTGCTGAAAAAGTGTTAAATCTAAATTTTCAGGTGGTCTGAAGCAAGGATGCACTTTT +TCTGTTTTCTATTGCCCTTGCCACATGGATGCCTTGTAATAATGGTTCCTACCAGTTTCT +GTTTCGTGGAGAAAGAAACAAGGGCAAAAGTAATAGCATTCACAGCATTCCAGCATATAG +ACCTCGAACAGAACATAATGATCAGGAAAAATAGCAAAGTAATTAAGCTCACAGAATTGG +GTGGGTTACAGGCTCTGCTACCCACTACCTGTGTGACCTTAGAGAGACTATTTACCCTCC +TCAAGTCTTGGTTTCTTCACCTGTCAAACTCTTAAAAGGTCTTTCCTTGTAAGATTGTTA +AAAGGATTAACCAGTGCATGAAAAGCACTTGGAAAAATGCCTGATAGGAGACCAAGTCCT +CAATAAATAGATGTTCGCTTTTGTTACTATTATTATCCTGTTTTAATTTAAACCTCACCT +TCCACCACCAAATGTGATACATTTAATGGCGTATCAACATGTGCTTTTCCTTTAATTTCC +CAAACAGGAAGCCAAACTATGTAGAGGCTTTTTGTTGTTGTTTTTAAATATCTCTTCTAA +GGAGAAAAGGAACTAACATTTAAGAAGTTCTTACTGTTTGCCAGATGTTTCATATATATC +TCATTTAGACCTCTCTATAATCAACAGAGTTACCATTTGTTGGTAAGATTTTTATTTGTT +GGTACCTATTCTCATCTTCAAAACTGCCTTACAGTGAAAACATGCTGTGCCTGTTTTATA +GATGCAGAAGCCAAGGCTCAGGGAGGTCACTTGATTTGCCAACGCCCCACAGCTAATGAG +TTGAGGATACAAGATGGGACTCTAGATCTGTGTGACTCCACAATCCTTGCAATTTCTCCC +ATACAGTGGGGAAGAGACAAACTATACCAGCCTACCTCCAATGGACTCTTGGCTGCACTA +TCAAACAAACCAGGAAAGTAGGTTTCTCCCCTCCCTTTCCTCATGTCAGCTGAGATTTTC +ATTGTGCCTTGACTAACTTCCAGTTAGGAATGTTCTGTGCTAGATTCCTAGTCTAGTTAG +TATGTATTGATCATGTATTTGGATGTCATTAGGCAAGTACTCATCATCAACATGAATTCG +TTATGTGCTTCTTAGGAAATTAACTGATAAAGGTTGGAAATCACTGAAAATCCTTTCCTT +TTTCAAGTGGTCATCCAATCTTTCCCATTATTCTCACTTTATTGCTCTTGGCAATATAGT +TAAGAATCTATTGACGTTAACATTGTAAACTCAATCTGTATCATGTCGTTTATAACTTGG +TCATAAAAATCCATTTATCCTGAGATTTTGGTGTAATTCTTTACTGGCTGAATTGTCAAA +ATTTTCATCTTATTAGTTATGTAATGCTAGAAAAAAATAAGACACAATTTCATTCCATAA +TAACCTTGGTTTTTTTTTTTCACTTGTTCCCAGAAAAATAAAGCAATAAATTTAAAATAG +AAAATGAATAATCTATAATATTAACTAAAGCATTTTTAGCTATTTAAGCATTACATCAAA +AGAAAATGTAAGAGTTTTTGTCAGCAAATTATTGAGAACCAAAATGTACTTGTGGCTTGC +AAGATTTTTTTTCAGTTTACTCACCAGTCTATATAAGGCAAGAGCCCTGATTATGTCCTT +AGGAGTCATTTCCATATGTTTACTAAATTATAGTCCTTATTTCTTCTTCATATCAACAGT +GACCCTAAAAATCAGCATGTGTGACCCTAAAAATACAGAAAAATGCAATGTATTCACTTT +TAGATACATTTTCATTTGGTGGATTTGGGGGGTTTGAGGTTATTTTGAAAATATATAATT +TATTTCCTAGACTATATAAAAAGGAGGCATCTAATAATCATTTACTAAAAATTAAAAGCA +ATTAGTGGCAGTTAGGATGAAGGCTTCAGTATTCAAGTCTGATGTAATGACCTTGCCCTT +AATTCAATATCCTTTGAGTTGTGTGTTTCTTCCCCTTTAGTTAACATAAATAGGGGCATC +AGCTTTACACCCTTAAAAAAACCTTGTTGCCCATCTTGTGAATCTTTTCTTTCTTCGCAA +TCTGTGAATAAACTGCTTTGCTTTGTCTTGTTAAAGCCAGGCCAGCCATAGCCTTGGCCT +TTAGACTACAGTATTTAAACTTTATAGGTAGATTTGACAAGCCTAAAGATGGATAATCAG +TCACATCGTTAGCACAAAAGAATTGCCCGATTAAGCAGGACAGAGACCAGCCTGAAACAG +ATCCTGATAGGCTGAAGGGATGTTCAAAAGATTTGCCTAGTTGGGGCCCCAGGTGTAAAA +AGCAAGCCCAGCATGGAAATGAGTAACTCAGACATATATGAAGGGGCTAGCGCAGCAGTG +ACAGGTGGCAGGAACCTACGGAACGAAGGGTGAATGGGAGCAAAGACCTTTAGATTAACC +AAGAGGCTTGCACGGAACAACAAGTGAAAAACAATTAGAACCCTGGAAGATAAAACCAAA +TGAAGTGATCCAAGTGAGGTCAGACAGCATACCAAGCAGCAGCACATCCAGTGACAAGAA +AAGTGTTTGTCCATGCAGGTCTTAGCTTCAGCCTCAGGCCAAGTTCGAATGGTAATGGGA +GTGCAATAGGTGGAGAATCTGCCTTCCACCCTCCTGCACCTTTTTATGGGAAGTCCGTGA +GATTCATTCATCACTCTGATACAAGAAGCTAAATCCAAGATACAGTTTTAGTTTAATACT +TTGAAGGTTTTAAAGTTTAAATGTGATTCCTACCCCTAAACAAGCAGAGCTGAGATGCCC +ACAGGGAAGGATGGGCCCCACGTCTCTCCATAGGCTTATGTGGTGTTTCTCTCCAGGTCG +GCCCAACCCCACATTCCCCCTCCTTCTCTGTCCTCTTTATCTCCCTCTACTGCCCTTCTC +ACCACAATACAAGAAACAGAAGCACAAAGTTTTAAAAACTGCTAACAAAGGGACTTTTTT +GAAACCAGTACTTGGAGGCGTTAATGAAAACCCAGGTTATTTCCAATTACAGTCTCAGGA +ATTACTGAATCCTTCCATGACCTTAGAAATGCAGAAGCCACGTGAAAAATCATCATTGGA +AAAGAAATCATTGAGAATCCCGTTAGGTGCCAGAAAAAAAATGGATGCTTAGGATTCAAA +GATAAAATAGATATCTGAGGCTATAAAGATGAAAAAGGTGTCTACTACCTTTAAGGAATA +GTGCTTATAGACGGACTGCTCTGTCATGCACCATACTGTTCTGTGTGGACAATGAGAGGA +GGTGCAAGACAATGGCCTGCCCTCAGAGTGCTTGTATTTTGGTTGAGGAGACAAGAAATG +CACATGGAAAAGGAGTGTTTGTTGTAGATTTTGCAGAGTCATATAAAGCTTACATTTCTA +TCTATGTCTATATCTTTATCTAGATCATCTGCCATAAGGCTTCAAAGGAAGGATAGTATC +TGAAGGCTTAAACACTCACAGAAATAAATTTCCATGGTGGGGGTTGTCCATGAGCAAGAT +CTTAAAGAATGGGTGGAGAGTTTAGGGAAGGACATATCTGGAGCAGAGACACCTCTACAG +GGGCAGGCATGTGGCAGTCCAGGGACCAGGGAGAACATGGACAGTGCTTTGCAAACAGAA +AGACTTCAGCTCTGATCCTGCCTCTGCTGCTCAGTCGCCAGGAGGACTTATGTAAGATCC +ACAGGTCTCCCATACAATTGAAGTAATAATAATAACAATAATACCTATGTACCAGATTAT +TAGATATATTCAATTAGATAACAGATGTAAATGTTTCTGGCCTTTTAATTATAACGTGTT +AATTTTAATTGTGTGTGTGTGCATATGTGTGTGGGAAGGTGGTATGTAAGTTTAAGACAG +TAAGTATATGATCCAGGAGTAGACATTTCATGTTGTGGAGTAAAAGCACATGATGGGGAG +ATTCTGAACACACTGTTGGGAGGTCCTGACTATAGTATTTGCAGTTAGCAGTGGGGAGAT +TCTGAACACACTGTTGGGAGGTCCTGACTACAGTATTTGCAGTTAGCAGTGGGGAGCCAT +GGAAGATTGTGAGGGAGAGAATGAGTGAGAAGTATTGTGTAAACTCTTTGTGAGGAAGCC +CCATCTGGCTGTAGCATGTCTGTGCAATTTAATTTAGGGGATATAAAATAGACACAGTTG +AGAAGCTATTTCAGAAGTAAAGAGGAAGCAATGGATATGGAATATGTCATTTTTTCTATG +AAATTCATTTATTCATTCACTCAAAATACTCATATTCATTGAGTACAGTTTGTTCTCAAG +CACTGTTCTAGGCATTGCACACTCAGCAAAGAAGAAAGCAGTCAAAATTCTTATCTTCAT +GGAGCTTTTATTCTAGAATAACTCCCTATTCATATAAAAGTACATATCTTCAGAAAATAG +AGTAAGAAATGTCGAGGAAAGTGAAATGTGTTAGGACAAGATATTTTAAAGCACGTCATG +TGATTAGTCTTTAACAAGTCCACCCAAGTCTTTTTCATCACTGCTTAATCTAACCTGGGT +ATGTCTTAGTCTGCTTCAAAGAGAAGCTCTAACATCTTTTCCCTGTGTTTTAAATACCAT +GCATAGCCTCCCAGTTGTATCCAAACCAATTCATAAATTTTTTCTCTCTGCTGCTGGATC +TGAAAGTCCCTGAAGGCATAGCTTCCACACATTTTTTGCCAGACTCTGATTTTGGTTTAA +GTATCTTACCTCTCTCCTGAGACACAACAGCCTTGCTCTTCTTCGAAAAGCTGTAAAATA +CCCTTCTGCATGCCCGTAATGACTTAATTTCCCCCCTTTTCAGGTCCACTAAGCAGATCT +GTTCTCACTCAAATACCTTTTTCTTAACCAATGAAGAAAGGATTCCTCTGGATATTAGGA +AAGAACTCAGTACATCCTCTTTCTGCCTCATGTTTGAAGTTTGGCTTTAGTAAAAGTTAT +GTTGCACAGAATTACTTAATGTTACTCATGAGCTTGTCTAAAGTCACTGTCTTTACCTAA +ACTTTTTTTTTTAATAAGAGCTCTTGTTTATTTTTCTCATCATTAAAGAAAAATTAACAA +ATAGATCTTTTCAAGAGGTAAGCAGCTATTGATTCATCCAAGAAATTGTAGGAGTGAACG +ATGATTTTTTTCAAATTGACAAGTATTCATTAAGCTAGAAATTGCTAATGATAAAAGTGA +ACTAGAAGACACAGGAGTATGCACTATGTGAAACTTCATTACCTAATGAAACATAAAAAG +CATGAACCTATATTAACAATTACCATTTCTGTGACTCTGACAGTCTATCTTTTATTGTAG +GACTTTGAGCAGTGCCTGGCACTTACAAAGCACTTAATAACAATCATTGAGTTGAATGAC +CTCTCATGTTCACAACAGCCCTGTGAAGTGGCCTCTTTTACAGATGAAGAAATAGAGGCT +CAGAAATCCAGATTGCAGAGCCATGCGTGGTAATGTCAGTATTGAAATCCAGACTTCTGG +ACACCACCACAGTAAATGATCAAGTACTAAACTTTGTGGTTCAAATTTTGAGTGTCTCAG +GAATTTGTAAGTGGGAAAGACAATGTGAGTTACAATAGTCAGCATCAACTTCATTGAAAA +GGTATGCTATGACTTGTCTATAATCTTAACCTCTTTGTCCTTTCTTAGCCTTGCTGATGT +ATTTTAAGAAATTTAAATGTTTGGTCTCCAGTGCAGTAGCAAATATACTTTTGAAAATTA +GCAGTCATTTTTACTTGGAATCAGGCATCCCTAAATGGCTCCTGTCATCATTTTGCACAT +TCTCGTGATTCCATAATGTTGTTTTCCTCACCTTGAATTTATTGACACCAATTCATTTTG +CCTTGACATTGGCATTAACAGGGAAATGGCTTTGTTTCATCCTGACATTATAAAATCACC +TCCCAAGACTTGGTTTGACATTGTCAGGGGGTGGTTATGGTGACAGCAAGGCCACAGCAG +ACAAGAGTGAATTACAGCGATTCCCTGGAAAAAAAAATCATTAAGAAAAGTTACCGCTGT +GTGATTTTAGTAGCTATTTTTCATACTTAAATATCCCTGCTGTTTAAAAATCCTAAGAGG +GCTTAGACCATATTTAGAACACTCCTACCAAGTATGTATAGGAAAAATTAAGTCTCTAAG +GAGACGTTTGGCTATAGCTTGACAAACAGGAACCTCAAATTATATTTTAGCTTTACAAAG +TGCTCAAAGGCATTGAAATTCTGCCTTTTAAAAAAACGCGTATTTGAATTGATGACACAA +TTATCTCCTTTCGGCTGCAGATACTTGCATTTCTTAATGCTGGGATATCAAAGGCCTGTA +GTATTTTCCTACCTCCTAGCCAGAATGTAGAATGTTTTACAAATTTGTCTTCAGCACTGT +ATGGGGTTGGAAAGATTGTCTTTCATAATTCCAACATCATTTCAAAGAACACCAAATCCT +TTTACTTGAGTTCTTCTATGTTCCCATAATGGTTTCTCACCTCGGCTGTACTCCCACAAA +GAACAGCTCCATGTGGATTTTCCTTTACCCTATGTTCCAAAGTTAACTAATCACCTTCTC +AATTAAATAAAAAAAGTCACTGAGATCCTTCAGGTCTTCAGGGCCATGTTGTTTTCACCT +TTGTGTTGCTAGCAATGCCCAGATTATAATAAGAGCTAATACATTTTGCTTAATGAAAAA +TGATAGGAAGGCCGGGTGTGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCAAG +GTGGGCGGATCATGAGGTCAGGAGTTTGAGACCAGCCTGACCAACATGGTGAAACCCTGT +CTCTACTAAAACTACAAAAATTAGCTAGGAGTGGTGGCGCGCGCCTATAATCCCAGCTAC +TCAGGAGGCTGAAGCAGGAGAATCGCTTGAATCCCGGGAGGCGGAGGTTGCAGTGAGCCA +TTATCATGCCACTGCACTCCAGCCTGGGTGACAGGATCAAAACTCCATTTCAAAAAAAAA +AAAAAAAAACAACGAAAGGAGCGTTCCTGATCTTTTATTTCAAAGCAATCATCCTTGCTG +CTTCTCCTCTCTTCCATCTTTTCCCCAAGTGTATATTGTTTCATGAAGAATGACTTAATA +CAAGTCACCATTCTCTTCCTGTTCATGCTTCCATTATCAAACCATGTGTATGGGAATCTT +TGACAATCATGGTATCCAACCTGAGTTGGCAAGTCAAAGCTGCTCAGCAAGTTTTCCATG +TGTTAGTTAGCTCCCTCTCCCATTCCCTGCCAAATAATTTTCCCTTTCAGCTAGCTAGCT +ACTAATAATAGACAGACATCCACCATTCGGAAACAGGCATACAACAAAATTTTATTTATT +TTATTTTATCTTATTTTATTGTATTGTATTTTTTGAGTCAGAGTCTCTCTCTGTCTCCCA +GGCTGGAGTGCAGTGGCACAATGTCAACTCAATGCAACCTCCGTCTCCCAGGTTCAAGCA +ATTCTCCTGCTTCAACCTCCCCACCATGCCCAGCTAATTTTTTGGTATTTTTAATAGAGC +CTGGGTTCGACCATGTTGGCTGGTCTTGAACTCCTGAGCTCAAGTGACCCTCCTGCCTCG +GCCTCTCAAAGTGCTGGGATTACAGGCGTGAGCCACCACGCCTAGCTTATTTGTTTATTA +TTTATTTAGCATCTATTCCATGCCAGGGACAGTGCTGAATACTAATGACAGCAACAATAA +ACAGGTAAAAGATGTAGTGCAGGTACGTACAAGGGCAGAAATAGTTTTTTTTTTTAATTA +GTTTAAATTCAACTTTGATCCCCTCTACTAGAAAGGTGGTGAGATATTCAGCCAACTGTC +ACTGTGGCTCAATCTACAAATGTAAAAATGTCCACTCATTTAGCACCAGTCTCTACTAAT +TACCAACAAGATGGTCATCCGTTGGGTTGCAGATCCCTTTAGCTCAGGAAGCTCTGATGG +TTCCATTCACATCTGAGGCTGTGGAGTCATTGGCAAGCCAAGGAATCAAGTCTAAGACCC +CTTCATGGTTATGGGATTGTGTAGAAACTCATGCCTTTTCTGAGATAATTGGTAGTCCTA +CTAGAAATATGTATTAGTAACACAAATACTGAAATTTGATAAAATGTGATTACATAATTC +ATTTCTTAACTGAATTACCTTTATTATCTAAGTAAAAGACACATATTTCTAAAAAAAACC +CAGCAATTTATTTTATTAACATTTTTAATATCACCAAAGGACTATATTCTAGGCAATTTG +GAAAGAGTGAAAAGTATAAAGATGAAAATTAAAATTACTAAAGTTTATTGCACTCCTACC +AGCTATAAATAAACACTGTTCACATTTTGGTACAATTGATTGTAGTATTTTTGCTAAGGT +TTATATTACACAGGTATGTGTAGAGTTACATGTCTGTACTTATGGAGATTATGCTGGATA +AACATTTTGTATCTGCCTTTCATCCTGGCACAATGCCATGTACTTTGAAACGATGATTTT +TACCCTGATATGTGTTGCCATTTTGTGTGAATATGCCTCCCCATGAATTCCATCTTTCAC +CTTCAGCTAAGAGTAGAGGTTGCAACTCTTATTAAACTAGACAAGTGCATTTTCTGATAC +CTGATGAGAAAGTCTGTGACTTCTCAGCACCATTTTTATGAGAACCTTGTCTGTGTCTGT +GTCTGAAGGTGTTGACCTAAATAGGATTTCAATACATCATTAATGATCACTTTGGGAGAG +GTGCCCAGCCTTCAGCTTGTAGGATTCTCAGTAAATTAATTCTTTCTCGATATCAGCAAA +GGCTTTTTTTCAGGTTGCAAAGGCCAAAAATTTTAGGGATGTTTGGGCAGGGCCTCCTGC +TCCTGCATCAGAGTCACCTGTCACCTCTTTCATGCTAGCCAGGATACTGTGAACTGCAGA +ATGGTCTCCTTCTAAATGAGTGAGGCTCTTTAATGGTGTTTTAAGCAGTTTTTTCTATGG +TTTGGCAAAAGAAAGTGTCACTCTCATAACAGGTGCTTTAATATTAGATGAGTAAGAATA +GAATGGCTACTCCCTAGGGTCAGAACTTGCAGTCCTTGATTACCTACATGTGTCCAACCA +CCCAGCCAACAGCTTCCACATTGTTCCCTATAGCAACTTCAGCTCTGACCCTTGGGTTCA +TTATGCTGAAACCAAGTAGGTCGGATGCTGTCACACAGAGTCTCGCCACCGAAGTACCAC +TGTCTTCAGATGCATACAGACAAACTTGAGTGTAAATTAAAAGCAGGAAAGCAAGGGCAT +TTTCACATGAGTCTACCAGGTTTCAGTCTGTTGTTTGCATCCGTACCTCCCCTGGCCCCC +TACACCATCAACATTGCAAAAGACAAAAGGTGGGCTATGGAGCAGTAGATGCAGGTTGAG +GGTCTCCAGCTCAGCCCCTCCCTGCTACTCTGGAAACACAGCTTATTTATGTGCTCTGAT +TGATACAGGAGAGTGCACATTGAATGAGAATATAGAAGTCGTCTTTGAGAAAATGGGCAC +TGCCACCCTAAGGTGACCTTGCAAGGCTTTGTAGAATATGCAGTAGTTGAATACAAATAT +TTGAGAATTGCATGTTTTGACCCCATGCTTGCTCAAGTTTCATACTAGCAGAAGACATGC +ACAGATGCTGTCTTTGAGGAAGGACATTTGCTTCCTTTTATACTTCAAGTAGCTTGGATT +GGATAAGTAGTGTTTAATTCATTATTCTGGCAGAGATAGGAATTAGCACCTCATTCTTCC +ATCCTGAGCTTCTAGCACTGGGTGGATTGAGGAAGAAATTGAACTTTAACAAAGTATACT +TAGGTTGTGTTTTATATTTTTTTAGAGCACCTCCACATAATTCATCTTGAGGCTACCAAC +AACTATTAGGTGGGTAAATAGGACAAGTGTTATTATCCTGCTTGTGAAGTGAAGAAAGGC +ACAAAGAGGTTAAGTGATTTCCCCAAGTTCACTCAGCCCATTAACTACAGGGATGAGACT +TGAATCACAGAATCTGAGCCTAATTCTCTTTATACTACCTCATGCTTTTAGTGCGTATGA +GGGAAAAAACTATCCCTGTTCCATGGGGCAGCAGATAAGACTGAACCAAAACAGATCAAA +CAGAAACAGTCACCTAAGTCATCACCAAGGACTCTATTACACAAGACCATCCATCATCAT +ATATTTGGTCAAGAAGGGGAGGGATTTCTAACACTTTGCCTTCAAAATGATAGGCTTTCC +ATTAAAAATATTCATGCAAATCATAAAACTTGAGAAAACTTTAGAAATACCGACTTCAAA +CCTGTAACCTGTAGCCTAACTTTACAGCTGCAACTAGAATACAAGCCCCTCATGTGCAGC +TCCACTGTGGGTCTGGCTTACCAAAATATGGCCACCATCCAGAGCAGTGCCTGGGTGGAT +GTTGGACAAACGCATGGATGAGTGTCACTAAATAGTTGCATAGTATGTCCAAGGCCTTGT +CGTAAATGGATGACTAGTGAGACCCAGATCTCAGGTTTTCCAGTTTTATGACGCTCAGCC +AATGTGTTTTCCCTTTGCACCATACTACCCCTCATGGCCAGACCAGACCAGACCATAAGG +TCGGGGAAGAAAAAAGGTTTTTTTTTGTTTTGTTTTGTTTTTTTGTGGGGCGGGGATGGA +TTGCAGTTAGTGTACCTAGAATTCCAACCACAACAACAAAAAGTGATTAGATAACAATCT +ATAAAGTTTCTTCCATGGCCCAGGAGCTAACCTGTAGGTTCAGTTTTCCATCTCACATAT +CACAACTTAGCAAAACAGCTGCAAAAGCTGTATAAATGGGTCATAATCACAGCTCTTCAA +CTCCCTGCCACACAGTCTCGAATGCCTAAATCAGACCTGAATGTAGCCCACATACCTTTG +TTATTAGCCTGTTTGGTGGAGGTTATTCACTCTTTGATGTTTCTTTGAAAAGGACGGGAA +CAATTTGGAACATCTTTCTCTCAGCAATCCTGGGCTTGTTTCAGGTGGTAAAGGTAGAGG +TCACTTTATTAATACAACCATCAAGAAAAGCTGTCATGGTAACGCATTACATTGATTCCT +TGAAGTGCAGGAGACAAAGCCAAAAAGAGAAACTTTCAAGTCTATAAATACAGACCCAGC +ATTGCTCAAGCATAGCAGCTCACTGACAGCATGAACCTAAATGTATAACGTTGAACAAAA +CCCAGAGAAAAGAAAACTTCCCTTTGGTAGTGGAATGGATCATCATGACCTTAGGGGAAC +AAGTGACCCCTCAGCTCATAAAAGATAAAAGAATAGAACAAGTGGCAACACCAAGTCCTG +GCTAATACCCTCTGAGCATAAGGAGTCCATCTGTGGTCAGTTTTTCCATACCTTCCAGAA +AGAACTCATAGAGGGGAAAGGAATCAAGGTCTCGTAAGTCACATTTGACAGTAGATTGCA +GTTTGAGAAGAGGAAATGTATGTGACAATCAAGAAACCCACCAAAAAAATGAAAGAATTA +AATAATTTAGCTATATCCCTGTGTCGCTCCTCATCCAAGATGGTGCAAGAAAAATAGATA +GAAGTAAGAGAGGAAGAAATGCTGCTTGATCAGTTCTTTCACTGTGGAAATTCTAAATGT +TTTTGTAAACTCATGGCAATTGTGAGAGCTTGTTTATCTACCTTGTGGCTTGCTTGCTAA +AGCTATGATCAGAGCTGTTACAACACCTTGCTGACTTCAGCTTTTCCACCAGGTTTCCAC +ACTTCATCTTTTGGCCACGTAACTCTGTTTGAATCTAACATTAATACTCTAACCTTATCT +GTCAAATTCCACAAATTATCTTGGTCACTCCATTTGAAATCATTCCTAATATCAAAACAT +CAGAGGATTATAGTATGTGATATTGGATACTCCATAAATGAATTATATTTATCAATACGA +AAAGGAATCCTTTAGAATACAGTCAAGCTATTACCAAAGCAGTATTAGTTTTTCTGGTAT +CTAAGGATCATATTTTACTATCACAAAAAGAAATCTGTCTAGCAAATAACTATTTGCATC +CAGCACTGGATCAAGTGTTGTATAAGGATTTTAAAATGAACCTTTCTGTTTACTGACATA +GGACACTCTAAGACTGTCAATAACAATAAAGAGAGAGTTGGGACATGCTTAAAATGAATA +CACCCACAGAATAAGTTTAGAGTTTTCAGTCTGAGGTAAACCCACAGAGCAGGGCACCAA +GTAAAAAGTGTGATCACTGAAAGATGCCTGTTGGGTAGAAATTTTCACTTGGATCTTTAA +TTTGCAACTATATGCAGGATTATGTGAGATAATGCCAGGATTGTAAATGGGTGTTTATCC +TCATGCCAGTACTATCAACTCATGGTGGATGCCTGGAAACTTGTGTTGAGAAGCATTTGA +AGTTCAGTGCAAGAGAGTCCCATGATTAACTAGCTGTATTTCTGACTTATTCCATTTTAT +GCACTATAACAGAATACCACACACTGGGTAATTTATAATGAATAGAAGTTTATCAACTCA +CAATTCTGGAGGCTGACAAGCCCAAGATCAAGGGGCTCACATCTTGTAATGGCCTTCTTG +TTGCACCATAACATGGCAGAAGGCATCACATGATTGAAGGGCAGAGAGAGAAAGAGGAAA +AGAAAGGGTCAGCCCACCCCATGATAACAAACCCTCTCCCAAAATAACAGCATTAGTCCA +TTCATGAAGGTGGAGCCCTTATGAGCTAAACACTTCTTAAAGGTCCCACTTCTTAATACT +GTTACAGTGGCAAATAAATTTCAACATGAGTTTTAGAGAGAACACACGTTCTGTACATAG +CAGTCTCCTATGTACAGGGGAAGAGGAAATGACAGTGTAAATGCAGACATATTTGCCATT +TTCAGCCTAGACATTGGCATTTCTGGTTTATTTTCTGTATGAGCTGATTTGTACTTGGAG +CTCTACCAAAATGTGGTAAAACCCTAGGATGAGTAACAATTGATACTATCAACAAAGACC +TCTGCCTAGTCAAAGTGTGATATGAAAGCAGAGCACTTAGTCAATACAGCTGCAAATCTA +CTGACTATCTATAGAAGAGTTCATGTCTCCCTGGTAAGTGGGAAAGTCAGCTATGTTTTG +AGGAGCATGGAATGTGGCACTGTGCAATATTATTTACCACATTTCTCCTGATTGTTCTTT +TCTATGTGAAGAGCAGTAATCTATAAATTGGGAGACCTGGATTCTAGTCCCAGTTCTACT +CTCAATTGCTTATCTACAGCTTCCTTATCTACAGCTCATCTAGATGGTTTCTAAAGTTTC +CTGCAAGCTCTGATTTTACTGCTTCTATGCAAGCAAATTACATAGCAGGGGTGCTTTTTG +TTCCTCTCACCCTTTCATTGTGAACAGTACTAAAGGGTCTGTCTTAGATCCCAGTCTCCT +ATATTTACTCCCTGAAGAAGATAATCCACTCTTACATTTCCAATTCAAGTACTTAGTCAC +CTCTAATTCCCACAGCTCAGCACCTGAAAACTTACTATCTTCCTGATCTAGAAATGACAA +AGTTTCTTTATTGTACCTTCCCCAAAATATATCAGGGACAACTGCCCTTCTTCATTGCTA +TGACTGATGCCCTGACCCAGGCCTTATCGTTTTATCTTTTACATTAATTGAGAAGTAATT +CTTTGTTGTGGGGGGTTGTTCTGTATACTGCAGGATGTTAGCAACATTCCTGGCCTCGCT +ATACACATCAGTGGCCAGTAGTGTGCCCTCCCTACCCACTTGTGACAACCAAAAAAAATG +TCTCCAGACATTGTCAAATACCCATGGGAGCAAAATCATCCAGCGTTGAGAACCACTACT +TTAGACTGACATCCAAAGACATCCATTAAATGTTAATTCTTCAAAATTTTTCAATCCTTT +TTCCAATTATTCAAGAACCCCTTATGACAGAGTCAATCAAGAACATGCAATGTTTATTTT +GCATATTTCATTTGTCCAACTCAAAGTGCCCTTACTGTCACACTTTTCCAGTTTGTCGAT +TCATAGATACAGTCATTCACATCAGGAAGACTTCTGCGGTTAATTTCATACCTTCATAGG +ATCACTGCATTTTTCTGACATTGTTTTCTTCTCAGCATCCTTTATGGTCTTTCTCTTCCA +ATGGCCTAAATGCTGATGTTCTTCAGTTTTCTATCTGTAGTCCTCATTTTTACTTGGTCT +ATATTCTTCTAGGATGAAGTCTTCTACTCTTTTTGATTCATCTTTTGCAACAACGACCAC +CACCACCCCAGCTCCAAATTTGTGTCTCCAGGATGACCTATCTCCTGTTCCATTAAATAG +TTTTCCAACTAATAACAAAACAGCTGCAGAAGAACCTTGACAGTTCTAAAAGTCAATAGG +TCCAAAAAACATTTCTCTCTCTCCTGACCAAACTCTTCCTCTTATCTTCTTTTCTCAATA +AATTTCTTTATTATGCATCTAAATACCCCAAACAGGAAGCTTAGACTCTCTCTTATCCAT +TCACATAACCTGTCTCCAAATCTTTTCCCTCCTTCCCTTCACCATTGTTCTAACCTCGTC +CAAGTCCATTCTATTTGAGTATGGTCTCCTTACCTCCAGTCTGCCGTTTTTCTGGTCTAG +ATTCACCTTCCTCTTCTCCTTTAAACACCACCCTCCTTCTAAGTCTTTGACAGCTTTCCA +TTCCTTATTACTAAACTCCACTGTGGCACCTTCACAACCAGGTCACATTTGCCTTTCCCT +TTGTGCATCCATCATTCCAGCCATAGCAGTCCATGCATCATTCACTAATGTGTCTTTCAG +TTGGGCTTCAGGCAGAAAACTGAAACCATTTCTAGGTATTTCAACAGAGAGAATTTATTA +AAAGAAATGGTTTAAAAAGTATTTGAAATTTTAAAGTGAGAACAGGATACTGAAGTAATT +CCTGTGTTAAGTAAGCAGGAACCATCTATCACTCTGGGACTGAGGGATTACAGGAAAGAG +GATTGAGTTATCAGAAAGTAAAAGTTTGGATAAAAGGGACCCCCACAGAGCTGAAACCTG +CACCTCTAAGGTGGGGTAATGGCTGGCTGCTGCAGCTGCCTCTGAAATGCTGAGTAGAGC +CTCCTTGGAGCTGAGGCTTAAACCTCTAGGGAAGGAGTGCCACCAGGCTGGTGTAGGAAC +CTCTAACGGTGTGATGAAGCTGGTTATGAATAAAGCTCAACACTGGAACCACATGTTGCT +GTTGATGTGAAGGGCCGTTGCTGGGCAGTACTGTTAGAGCACCATCAAACAGAGTCAAGG +AAACAGGATCTTCCATGCCTCCTACTTTCTCTGCTCCCTCTAGTGCCCCCTGTTGGTGGG +ATCCAGCAGACAACTTGCAGAGTTCTGGCCTCAACATCAGAAGGGTGGATTTAGAGTTAA +AAGACAATTGCTTAATAACCAATACAGTACACTTTCACATCTCCTTGTCTTTACTGATGC +AGTTTCCCCATTTATAATGGCTTTTCTACAAGTATCTGCCTGATGAATGCCTTTGCTCAA +ATACAATCTCTTTTTTATAATCTCCCTTAATCTTCCCAAAAGTAATTATTTATACTATCA +TGTGAGTTTCCCCAGTAATTTGTAAATACGTTTTTTGTAGATTTTTTTTATACTATATCA +TAATATGTGTTTGTGTGTTTATTTTCCATTTATTTTCTGCCAAACCAGGTACTCCTTTAG +GACAGTTAGTTACAACCATAAAATATAGCAGGGTGCCTGGCATACAACAGATATTGGTTA +AGCTCAATGGAATTGATAAGGGCATTTTAATGACATTAATATTAGATCATTTCTTATAGA +TATTTTATCATCCCAGCCAGATTTAAACTTCATAAGAGCAGAAATCATCCTTTATATTTC +TTTTATTTTCTTTGCGGGGTTAAGTGCAAGGTTGAGCACACTGAAGAAGAGCTCAGTGAT +ATTTGTTAACCACCTAGCTTGTTTATTAGCTACCACAATTTTGGTTCAAAATGACATGAA +GATGGAGCATGATTATGAATATCAGGTAAGATCCATAATTAGGTTAGATGTGCTTCTAGC +CCATGATTCCAACAGTTAGAGGGCACTGTATGTATGGTAAAGTTCTGTATTTGTTGGAGG +ACTAACACAATCAAGAGACCAAATGTAATATGTTTTATAGTGAATTCTAAATAATGAAAT +ATATTATAGGTTTTATTTTTCTCTATTGATCTCCTACAGAAAATATATCCTGCCAATCCA +TGAGATTACTAATTCTGGGCTATATCTGTTCCTAGTATATTTATTAAATTTCTCACAACT +ATTAAAATCAACTAGTAATTACTTAAATGCAGGAAAAATATTGAATTTTAACTTAATCAC +CAGCTTCTTGAAAAAAGAAACCTCTGTTCAACAGCTGATTTATATTCACATCCAAGAAGA +AGAAAAATAGCTTTTTTTTTCTAAAGGGGAGTGATATGTAATTAACTATTGATTTCTTCT +CAATTATTCAAGGCAAGCAATTATCGATATTGATGGAACAGATATTTCCCTACCTCTAGT +GCCCAAATGAAAGGAAATATCCCATTCAGCATTCTGCTGCCTGGAACAAGAAATGCTGAG +GATCTTCAACTTTAGCTGAAAACAGTTATCTGGATCTGTTTATTCCATGTTGCCCCAATT +AAACATATTTCTTCAAGTGCAAGCAAAATAAAATCCTGAAAACCTACATATGCTTTCCAA +ATTAACTAAAGCCAAAAAACAAGAGCTTTTGTCAGTTTTGACCATGAGGCTAACCACCCT +ACATGTGGACTTTGCTTCACAGCTACAGATCTTGACATTTTTAACCATGACTCATAAAAT +AATGTGGTTCTAATATTATGATTTCTAAGCCACTCAATAAGAGGTAGCTTATATAATCAT +TAGAAACCATGGAACACTGCCTTGCATATCAATATTTGGAGCCTGAAGGATTTAGTAGGC +CTTAATAGTCACTTCTGACATTTACAGATAGCAAACGTGGATACATTTGAAAATTATGCC +AATACACTACGCAACCGTGTTAGAGGTCACCAAGGAAATGTTGAGGAAGGCAGTAAAACA +GTGGTCTATTTAGGGCACTCTGTTATTAACCATGTGGGTATCCACCACCATCTTTCCTAA +GCTCATTGACACACAAAGCACTGGCATGTTTGTGTGTAAGAAGCTTCTTTTGAAGCTGAC +ATGACTGTTGAACATAATTAGTGGACAAGGCAACATTCTCTATTGAGTTACTACTTGGAG +GGTAGAGTTGTTTTCTTTTAATACTTTGCACTTAATAGTAATATTGGGTATGTGTATATG +AGTGTGTAGTGTGTTGAACTCATGTGGCATCCCTGGGGAAATTTCACCATGACATTTTTA +AAAATGGAAAATGTTACAATTTATAAAAAGCTACTTTTTCTGCTCTGTTCCCCACCTCCC +ATTCCAGAGGGGTTCTATATATTAAATGCTTAAGCAGCATATGTTGCTTGGGAAATGTTC +TTGGCTCTTTTACTCTTTGTTGTTGTTTTAATTTCCCTGGGTTCTAGTTAACATTCTGCT +AAATCAGTGAAACAGTGATTATCTAAAAGAATAGGAGACATGGAATTAATGAGGTTAGTC +AGAATTTTGAAGAAATAAGAAATTATTAGAGGTGAAAGTTACATGACAGGGTCTGTGAAT +GAATTCTAGTCTCTGAAGTTGCTTGTCTTGATTTATTCAAACTGATTCCATTAATTGATG +GACATAATGAAATTTTGGTAATCAGGGTTTCACCATCGCATTTATTACTATTCCCGGAAA +TCAAGGTAACCTTGGGCTATACTTCCCATATTTACAAGGTGATAAAAATCCTTAATAGGC +TGTCAGGGACGAATGTGACTGCTTTTCCTCACACTCCTCCCATGAAACAAGCTTTCTCTC +TTCCCATCTGGCTGCCGCCTGCCTGGAGCATGCTACTTTCCCCGTGTCCCCACCCCTCCT +CATCCCCATGCCTCCCGGTGGGTTCTGTCTTCATGCATGCAGCGCTGGAATCACGCACCG +AGAGAATGGCCCACCCCTTAGAGGTTTTTGGTCATTTTAGCAATACCGCTTTGCATTTTA +AATACCATTCATCTGGCTTCAAAGATCTGCACTCTTGCATCGGGCACTTGTCCTTTAAAA +ACCCAAAAGATCACAACAGGTCCCAGTTCCATGAAGAAAAGATACTGCCAAACTAGGACT +ATTGCATTACTTTGTATTCTATAGCCTGAAATGGACAATGATAACATCCAAGATTGCAGC +AAAAATCTATATGAAAAGGACTAATATGATAAAAACAAAGGCAGAAAACTACATTTGTTT +GGAAATTGGAGTCACGGGCTTCGTTTGTGGAGGGGAGGGGGGAGCACAAAGATCGATAGA +GATTTTTTTTTTAGGCTGAAAACATGATGTACCAGATGAACTTCAATTGATTCTGCTTCT +CCTCCCCGCGCCCACCCACCCCTACCTTCCCCCTCATTCTGCAGCGAATGTCTGCGACAA +CGAGCTCCTGCACTGCCAGAACGGAGGGACGTGCCACAACAACGTGCGCTGCCTGTGCCC +GGCCGCATACACGGGCATCCTCTGCGAGAAGCTGCGGTGCGAGGAGGCTGGCAGCTGCGG +CTCCGACTCTGGCCAGGGCGCGCCCCCGCACGGCTCCCCAGCGCTGCTGCTGCTGACCAC +GCTGCTGGGAACCGCCAGCCCCCTGGTGTTCTAGGTGTCACCTCCAGCCACACCGGACGG +GCCTGTGCCGTGGGGAAGCAGACACAACCCAAACATTTGCTACTAACATAGGAAACACAC +ACATACAGACACCCCCACTCAGACAGTGTACAAACTAAGAAGGCCTAACTGAACTAAGCC +ATATTTATCACCCGTGGACAGCACATCCGAGTCAAGACTGTTAATTTCTGACTCCAGAGG +AGTTGGCAGCTGTTGATATTATCACTGCAAATCACATTGCCAGCTGCAGAGCATATTGTG +GATTGGAAAGGCTGCGACAGCCCCCCAAACAGGAAAGACAAAAAACAAACAAATCAACCG +ACCTAAAAACATTGGCTACTCTAGCGTGGTGCGCCCTAGTACGACTCCGCCCAGTGTGTG +GACCAACCAAATAGCATTCTTTGCTGTCAGGTGCATTGTGGGCATAAGGAAATCTGTTAC +AAGCTGCCATATTGGCCTGCTTCCGTCCCTGAATCCCTTCCAACCTGTGCTTTAGTGAAC +GTTGCTCTGTAACCCTTGTTGGTTGAAAGATTTCTTTGTCTGATGTTAGTGATGCACATG +TGTAACAGCCCCCTCTAAAAGCGCAAGCCAGTCATACCCCTGTATATCTTAGCAGCACTG +AGTCCAGTGCGAGCACACACCCACTATACAAGAGTGGCTATAGGAAAAAAGAAAGTGTAT +CTATCCTTTTGTATTCAAATGAAGTTATTTTTCTTGAACTACTGTAATATGTAGATTTTT +TGTATTATTGCCAATTTGTGTTACCAGACAATCTGTTAATGTATCTAATTCGAATCAGCA +AAGACTGACATTTTATTTTGTCCTCTTTCGTTCTGTTTTGTTTCACTGTGCAGAGATTTC +TCTGTAAGGGCAACGAACGTGCTGGCATCAAAGAATATCAGTTTACATATATAACAAGTG +TAATAAGATTCCACCAAAGGACATTCTAAATGTTTTCTTGTTGCTTTAACACTGGAAGAT +TTAAAGAATAAAAACTCCTGCATAAACGATTTCAGGAATTTGTATTGCAATTTCTTAAGA +TGAAAGGAACAGCCACCAAGCAGTTTCACACTCACTTTACTGATTTCTGTGTGGACTGAG +TACATTCAGCTGACGAATTTAGTTCCCAGGAAGATGGATTGATGTTCACTAGCTTGGACA +ACTTCTGCAAAATATGAGACTATTTCCACTTGGGAAAAATTACAACAGCAAAAAAAAAAA +AAAAAAAAAAAAAAAATCTAAGTGATTGCCAAGATTATGCCAAAGCCTGTTGGCAGAGTA +CTAAGAGACTTTTATTTTTAAGTCATGCTATTTTCACAGATTGATGGTGATCATGTGACT +CTAGGGATGCTGATCTATGTATCTTTCCAAATACAGTGTTTACATGGAGTATCACAAGAC +GCAACCTGGGGAACCAGGAAGGGAGCAGGGAAATTGAGTGATTTGCAATTTGACTTTGAA +TATATTCAGACTTAAGTATTTAGAGGAAATATCAAAATATAAAGCAGCAAGTAGACATAA +CTGCTGTTCCTGAGAATAAAGTTTGTTTTAAGTGCTGCCCAAGGTGTAATAAATTCTTGT +TTCTGCCTTTTATTAGGCCAATTACTGTGCAAGACAGCAAGGGGAGGCAGGTGGGGAAGA +ACCTTTGCAAAGTTTCAAAGAGGCTAAGACAGTGTGCATTTCGTTCCCAGCACACTGTTG +TCCTACAGATTACAAGTGTATTAGCAGCAGCATCTCCTGGAATCAAAAACAATTATCAGC +CCGAACCAGAGTCTTAAGGACAATGAAATTCTACATGACTTGGTAGAACAATAACCTATG +ATAGTGTAAGGTCAGAAACCTAGTTCCAGTCTGAATTCTTCACCCTGCTGCCACTCCTTG +CTGAAACAGGGAAGGGGGGAGGAATGTCTCCTGATAAATAACCTGGGTAAAAACTAGATG +AAGGAACAGCATGTCTTATTGGTTTTGTTCCCAGAAAAGCCAATTCGAAGAAGGCAATAA +AAGGTAAACAGGTAATGCCTGTGCTGCCTGCCACCCCACGTCTAAGTCTATTGAATGTTT +GTTATTCAAACCAACAGTCTCTTTTGATGTAAGAAATAAGGAAAGATGGAAATAAATTAG +AGCTTAGGCTTAGTGCCAGAGTGGCCAACCAGAAATTGGAGATTTACGTTGGAAGCATAA +ATAGAAAATTATATTTCAGGCTCACCAAAGAAACACATGAAAATGCTGATAACATAGGGA +GTTTGAGATTATTTATAATGAGGTGGATTTCTGATATTAAAATTAGAGTTTAAGTTGTCT +TATAGTTTATTAGCACAAACCAAAGGCAGCCCATGTTATTTCTGGCAAAGATGCACTTTA +TCGTTATCTGCTCATGGCTTTGTCGCAACGCTCAGGAATCAGACACTGCACACTTCAATA +GTTGGGATTCCAAAAGCTAATTCTAAAATTTAATGAAGGCCTGATTTAAACTGATTCATC +TGCATTTTATCTTTATGAGGCCATAAGAATCTAAATTGATGAGGAATATCTTTCATTCCG +TGTATTTAGATATAGTTTTCTGAATTTCCTGAAGCGATGTGATCTGCTTTTAATAAAAAT +TCACTTTTAGGT diff --git a/test/csq/ENST00000542803/ENST00000542803.fa.fai b/test/csq/ENST00000542803/ENST00000542803.fa.fai new file mode 100644 index 0000000..473705b --- /dev/null +++ b/test/csq/ENST00000542803/ENST00000542803.fa.fai @@ -0,0 +1 @@ +1 343452 25 60 61 diff --git a/test/csq/ENST00000542803/ENST00000542803.gff b/test/csq/ENST00000542803/ENST00000542803.gff new file mode 100644 index 0000000..88d751c --- /dev/null +++ b/test/csq/ENST00000542803/ENST00000542803.gff @@ -0,0 +1,22 @@ +1 ensembl_havana gene 1 343452 . + . ID=gene:ENSG00000162631;Name=NTNG1;biotype=protein_coding;description=netrin G1 [Source:HGNC Symbol%3BAcc:23319];gene_id=ENSG00000162631;logic_name=ensembl_havana_gene;version=14 +1 ensembl_havana transcript 11 341464 . + . ID=transcript:ENST00000542803;Parent=gene:ENSG00000162631;Name=NTNG1-206;biotype=protein_coding;tag=basic;transcript_id=ENST00000542803;version=1 +1 ensembl exon 11 193 . + . Parent=transcript:ENST00000542803;Name=ENSE00001711486;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001711486;rank=1;version=1 +1 ensembl five_prime_UTR 11 193 . + . Parent=transcript:ENST00000542803 +1 ensembl five_prime_UTR 8063 8587 . + . Parent=transcript:ENST00000542803 +1 ensembl exon 8063 8833 . + . Parent=transcript:ENST00000542803;Name=ENSE00003594347;constitutive=0;ensembl_end_phase=0;ensembl_phase=-1;exon_id=ENSE00003594347;rank=2;version=1 +1 ensembl CDS 8588 8833 . + 0 ID=CDS:ENSP00000440561;Parent=transcript:ENST00000542803;protein_id=ENSP00000440561 +1 ensembl exon 184276 184916 . + . Parent=transcript:ENST00000542803;Name=ENSE00003471810;constitutive=0;ensembl_end_phase=2;ensembl_phase=0;exon_id=ENSE00003471810;rank=3;version=1 +1 ensembl CDS 184276 184916 . + 0 ID=CDS:ENSP00000440561;Parent=transcript:ENST00000542803;protein_id=ENSP00000440561 +1 ensembl exon 255148 255324 . + . Parent=transcript:ENST00000542803;Name=ENSE00001451664;constitutive=0;ensembl_end_phase=2;ensembl_phase=2;exon_id=ENSE00001451664;rank=4;version=1 +1 ensembl CDS 255148 255324 . + 1 ID=CDS:ENSP00000440561;Parent=transcript:ENST00000542803;protein_id=ENSP00000440561 +1 ensembl exon 255456 255472 . + . Parent=transcript:ENST00000542803;Name=ENSE00001620095;constitutive=0;ensembl_end_phase=1;ensembl_phase=2;exon_id=ENSE00001620095;rank=5;version=1 +1 ensembl CDS 255456 255472 . + 1 ID=CDS:ENSP00000440561;Parent=transcript:ENST00000542803;protein_id=ENSP00000440561 +1 ensembl exon 263634 263639 . + . Parent=transcript:ENST00000542803;Name=ENSE00001659820;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00001659820;rank=6;version=1 +1 ensembl CDS 263634 263639 . + 2 ID=CDS:ENSP00000440561;Parent=transcript:ENST00000542803;protein_id=ENSP00000440561 +1 ensembl exon 290744 290911 . + . Parent=transcript:ENST00000542803;Name=ENSE00001451661;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00001451661;rank=7;version=1 +1 ensembl CDS 290744 290911 . + 2 ID=CDS:ENSP00000440561;Parent=transcript:ENST00000542803;protein_id=ENSP00000440561 +1 ensembl exon 296659 296793 . + . Parent=transcript:ENST00000542803;Name=ENSE00001451660;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00001451660;rank=8;version=1 +1 ensembl CDS 296659 296793 . + 2 ID=CDS:ENSP00000440561;Parent=transcript:ENST00000542803;protein_id=ENSP00000440561 +1 ensembl CDS 340605 340834 . + 2 ID=CDS:ENSP00000440561;Parent=transcript:ENST00000542803;protein_id=ENSP00000440561 +1 ensembl exon 340605 341464 . + . Parent=transcript:ENST00000542803;Name=ENSE00001595215;constitutive=0;ensembl_end_phase=-1;ensembl_phase=1;exon_id=ENSE00001595215;rank=9;version=1 +1 ensembl three_prime_UTR 340835 341464 . + . Parent=transcript:ENST00000542803 diff --git a/test/csq/ENST00000542803/splice-region.txt b/test/csq/ENST00000542803/splice-region.txt new file mode 100644 index 0000000..a120c4c --- /dev/null +++ b/test/csq/ENST00000542803/splice-region.txt @@ -0,0 +1,3 @@ +263634 G A missense|NTNG1|ENST00000542803|protein_coding|+|361C>361Y|263634G>A,splice_region|NTNG1|ENST00000542803|protein_coding +263634 G A missense|NTNG1|ENST00000542803|protein_coding|+|361C>361Y|263634G>A,splice_region|NTNG1|ENST00000542803|protein_coding + diff --git a/test/csq/ENST00000542803/splice-region.txt-l b/test/csq/ENST00000542803/splice-region.txt-l new file mode 100644 index 0000000..a120c4c --- /dev/null +++ b/test/csq/ENST00000542803/splice-region.txt-l @@ -0,0 +1,3 @@ +263634 G A missense|NTNG1|ENST00000542803|protein_coding|+|361C>361Y|263634G>A,splice_region|NTNG1|ENST00000542803|protein_coding +263634 G A missense|NTNG1|ENST00000542803|protein_coding|+|361C>361Y|263634G>A,splice_region|NTNG1|ENST00000542803|protein_coding + diff --git a/test/csq/ENST00000542803/splice-region.vcf b/test/csq/ENST00000542803/splice-region.vcf new file mode 100644 index 0000000..12ecb0f --- /dev/null +++ b/test/csq/ENST00000542803/splice-region.vcf @@ -0,0 +1,6 @@ +##fileformat=VCFv4.2 +##contig= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO +1 263634 . G A . . EXP=missense|NTNG1|ENST00000542803|protein_coding|+|361C>361Y|263634G>A,splice_region|NTNG1|ENST00000542803|protein_coding;type=ENST00000542803:107946262-G-A diff --git a/test/csq/ENST00000543077/ENST00000543077.fa b/test/csq/ENST00000543077/ENST00000543077.fa new file mode 100644 index 0000000..e564d18 --- /dev/null +++ b/test/csq/ENST00000543077/ENST00000543077.fa @@ -0,0 +1,292 @@ +>12 12:4537321-4554780 +TTCCAAGAGAACATAGATTTATTTGGAACCCAGAGTTGCTCGACTGAAGGCACATTGGGA +TCACCCCCAGAGATGGCATGAAAGGGGCGAGAGAGTGGGGATGGCCACAGCAGGAACGTG +GCACGGAGATGACAGGGCTGATGACGGGAAGCTCAGGAAGGGGCAGTGTGAAGGGAGGGA +GGAAACTCGGGAGGCTGTGGGGTCCTCCTGACGTAAACTCTCCAGTCATCTTCTTTCTTT +TTATTTAACCTATAAAAAGATGGCATAATTTATAGTCTCTCCCAGCTCAAATGTCCTGCC +ATCCCAGTCATCCTACTAGATGGGTTCTTCAACGTCAGACCCACCTGGGATGTGTATTAA +ACGTGTAGACTCCTGGGCATCGTCAGAAAATCTGGGAGCGGGACTTGGAGATCTATGTCT +TAACGTGCTCTTGGGTGATTTTTTGTAATGCAAGTTAATGAGAGCATGGGGACTGCATCT +ACCTTGTTCACATGTGTATCCCAGAAACCTAGCCTAGTCCGGGGCAGGGTTGAGGAACTC +AGTATATCTTGATGGGTGAATAAATGAATGAATGAACTCTATAGTCACAGAATGTGTATA +TTTGGTTTTGACCAAGGCAGAAAAGGAAGAGGGATGCTGCCTCGCTATAGTCTTCCATCG +CTGTCTTCACCCTCCTGGGCCAATTTCCCCATTGGCAAGCTACAGGGTAGTTGGACTGAG +TACGCCACAGGACTTCTTCCTGCCTTAATAATCAAGAGCACCATGAATCGGTGCTTTCGG +GTTCTCTTTGCCTGCCTTCCTGCAAGGGGGGAAAGAATCAAGAGGAAAATCAACGGCAAC +CCAGAGATTTGTTGTCAGTTTTAATAGGAGGAGTGGAGTCAAAGAGTTTAGAGAAATGTA +GAAAAAGACCTTTTACTTTTTGCTGGAACATGATATGGTTTGTGCATGGCACATACATAT +TTAAAAAAAAGACGTATCACATTTCACAACCACATGACCGAACAGCATCTGGGTTGTGCT +ATGCGCTGTGCCTAGGCTGGAGGGCAGCTCTACCCTGGGACCAGCCTGAGGTACTCAGCG +ATTTACAGAAAGAGGAAACCACGCAGGACACAGCTCTCTGGTGCCGGAATTTCAGTCGTT +CAATGAGGTATACAAACATGGTTCTGCGTTGGCTATCTGCATGATGGACCAGATTCAGGA +CCTGCTTGGGGCATAATCGCATCCTCCACCTGTTCTGGGAAGAGGAAGCATCAACTCAGA +TGTGAGCAGAGACTGGAGTATTTCTCTCTATTCTTCTGGCCTTGTCCCAAACATTCCTCT +CTTTGGAGTTTTGCAGGGAGGTAGCAGAATGAGTGGCTGGTTCCTTCAGGGGACGAGCAA +GTATTAGAGACCCACTTTGTAGACACAGGCATGGTAAGTGGCAGAGAATGCTTCCTCAGT +GACAGCTGACCCAGAGTCTTTGAGGAAAAACATTGGGATAGAAGGATGAAGGAGTTTTCT +TTTTTTATTTTTATTTTTTGAGACAGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTG +GTGCAACCTTGGCTCACTACAAGCTCCGCCTCCCGGGTTCACGCCATTCTCCTGCCTCAG +CCTCCCGAGTAGCTGGGACTACAGGTGCCCGCCACCAGGCCCAGCTATTTTTTTTTTTTG +TATTTTTAGTAGAGACGGGGTTTCACCATGTTAGCCAGGGTAGTCTCGATCTCCTGACCT +CGTGATCCGCCCATCTCAGCCTCCCAAAGTGCTGGGATTACAGACATGAGCCACCGCTAC +CTGGCCAATGAAGTTTTCTAGCTTGTGTCCACATGAAAGGGACAGAAGGAGATAGAGGGC +AGAGGGGAGATCCTCGTGTCTTGGAGGACATTTGTAGATGTGCATTTTAGTAGATATGTT +TGCACCAGTGACTGTGGCACAGAATGGGCAAAGGCAGTGGACAAGGGGAGAAAGGAGAAC +TATAGCTCATGGACTCTCCTATTTCTTTTTTCTCTCAGGACTTGCATAGAACAAGAACTT +GAAGGGTCTGAGGTCTAGGACAAGAAAGTGGCCCAGAGCCAGCGTTGAAGGAGAATTGCA +AACTGCCCAGGACAGGATGAGGTCTGGAGAGAATTTCAGGCCTGGGTTTCTGGGCAGGAG +AGGTATCTGTATGTCTAAAGAGGAGAGAGGTTTGGCCGGGTGCAGTGGGTCACGCCTGTA +ATCCCAGAACTTTGGGAGGCCGAGGCGGGCGGATCACGAGGTCAGGAGATTGAGACCATC +CTGGCTAGCACGGTGAAACCCCATCTCTACTAAAAATACAAAAAATTAGCCAGATGTGGT +GGCGGGCGCCTGTAGTCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATGGTGTGGACCCT +GGAGGCAGAGGTTGCAGTGAGCCAAGATCACGCCACTGCACTCCAGCCTGGGTGACAGAG +CGAGACTCTGTCTCAAAAAAAAAAAAAAAAAAGAGGAGAGAGGTTTGTACCCTGAATCAG +AAGGCAGAAGAAAATGTTCTTTTTGTTAGGCCATAGACTGGCCCTGACCAAGGGCTTGGC +ATGTGTATTAGGGCACTGTGGGATGTGGCAGCAGAGGGGAAGGCTGTGGAGGATGATGGT +AGGGTATGAATTAGAAAATTACATGCTGCTTTCCCGAGAGGTTCAAAAATGTATGGGAAG +TGGGAAGGGAAGGGGTGTTACAAGGCAGTGAATGATGAAACAAACATAATCAACAGCTTG +AACAAGGCATTTGGAGTTTTCTGGTTTCCTATGAGGTTCATCCATTGCCCTGAAACGGGT +GGAGGTTTTACAAGGAGCCCGAGGCTGCCCCATTGCTTCTAAGCTAACCTCTAAGGCTGC +AGCTGAGAAGTGCATCTTGAAGAGTGTGCAGATATGCTGCTCTCCTCTTTATTATTTGCT +CTTGAAGAGAGAATAAAACAGCCTCTTGGCCCTTGGAACTCCAAGTTTGCATGGAGCTGC +CAAAGAAGATTCAGGACGAAAGAGAGGTGAATTAGCTACAAAACTCTATAAACCAGGCTC +ATTGCTCAGCACTTGGGGGATGGAGGGCCCAAGTCTCAGTACATCCTCAGTGGGAAAGTG +GGGTACACTCTGGCTCCCCTGCATATAGCAGTGCCTTCTGCAGCCTTTGGGAGCCAATGG +GCCTGACAACTGAATTCAGGACTCAGTGGACATGTGACCAGATAGGAAACAACTCTCCAT +GCCCGGGCACAGAAACGGAAGCTGGAGAGAAGGGGCTGAAATGCATCCTGCTGATCTTAT +TCTGGTCTTGTCCCTTAGCTCACTTCTGTAGATGGGGATTGACTTTTCTTAAGTCTAAGT +CACTTACAGGAAAACAGAAAGCCCTTGAGAGAATTCCTTTGCATGGGAAGGATTTTAAAG +AGTCACCCACACATACCTGCATCCAAAGGTGGTATTCAAAATACTTAGCAACCAGCTAGG +TGTCGTGGCTCATGCCTGTAATTCCAACAGTTTGGGAGGCTGAGGCGAGTGGATTGCTTG +AGCACAGGCGTTCAAGACCAGCCTGGCCAATATGGCAAAACCCTATCTCTCCAAAAATAA +ATATAAAATTAGCTGGACCTGTAGTCCCAGCTACTTGGGAGGCTGAGGAAGGAGAATCGC +TTGAGCCTGGGAGGTGGAGGTTACAGTGAGCCGAGATCACACTACTGCACTCCAGCCCGG +GTGACAGAGCGAGACCCTGTCATAAACAAACAAACAAACAACCCCCAAATACTTAGCAAT +TGATACAGCATGGGCCCTGGTACCAGTTAGACAGACACCCAGCCCCTCCTAACCGGTGCG +GGTGCAACTGCTATGCAGTGGCTCAATATCATGCGTGCTTGATCATAGGCATTTCGTAGC +TTCTGCTTCCCACTCCTAGCATGAAAAATGAAAGTGGACATTTGGGGAAATGCCTTGCCA +GGATTTGAGCAAGGTTATGATCCTCTAGAGAGATGAAGGACAAGGCTGGCAGCCCAAGGC +TTTGGAGACTCTCTTGAAGATGGCTCCTTTCCTGCCACGTGAGCTGAAAGATCTTGGAAA +AAAGGAAAGCATGCTATGGGACCTAAAACTTCCTTCTCCTTTTTTCTCTGGATCACAGTC +ACGCCGTCCGCCAGCCATCCCACATTCCAAGCTCCACTAGGAACTGATATGCACCTCAGG +TTTGGAGTGCCTGCATTTCTGATGGACCCTGTTCAAGAGACTGATTGCACTGGACAAGAC +TCCCTAAAAAACAGTGGAGAGCTTTATCCCCGCCTCCAAGCAGACCCACACTTCAACATT +CCACGGAATCAAGATGGACCAGTTTTCTCCCTTTTCTACAACATCCAAGGGTTGGCCATG +TGCACACGTGTTCCGAGGCTTCTACAGTCTCTTCCATCTTCATGTACCTGGGTGTGGCCT +TTTCTTCCTCACCCAGCACATGTCCTCCCTGACATTTGCAGGGCAGAGGAGGTGGCAGGT +AAGGTGTCTCCCCCTTCGATTGCCAACCTCCCATCTTCAGCTCAGAATCCCTCAACCCAG +ATCTATCTATAGATGGATGCAACTGCAAATAGCGAGGTATGTTGAAGATGAAGGTATTTG +CAACAGATGAAGGATTGTCTTGCAGGCCGGGGCCCCCAAGAGTCGCAGAGGTCATCAGGT +CATTTTGTAACTCCATGGTTCACATATGCCAAAAATATTTGCACTCTGATATGGCTCTCT +CTGGTTTCAGATTTAGGAACATTCCAATGGTTCAGGAATCTGAAGGCTCCGGGCAGACAA +CATTTATAGTCACTTGGGGAACCTCTGCTTTAAATATTCTCAAAGGACAGGAGGCAGAAG +GCACTGTGCAGCAAGGAGCTGCTTCAGCTTGGCTGCTTGACTCTGTGGGATTATCACTCC +TCTTCTACTGCAGGGAGGAAGAGAGCACAAACTCTGGAGGTCACGGTGCCCATTCTGCTG +CATCCAGGCACAGCGCGTATGTGAGATGAGGATGAGCAAGAAGGAAGTGAGGGTATCAGA +TGAGAACTTGGGTGCGTTTCTTGGACATAGTTGGAGAGGAATTACCATCTGTAGTCCAAA +GCCTCTCTACTTCCTTCATGCCCTATTTTGTCCCCCTACTCCTCGCCAAAGAGGTTGCCA +TTATTAGGATCCTTGTCATCTGAGGTTAAAATAAGACCAGTTCAAAGTGAGGAAACGTTA +TGGGCAGGCAGCCTGGCCCCTGCTTGTTCCTGGAGCCATGCACAGCCTGAGTTCTCCAGG +CAGAGTGGCTCTCCTAGAACATCCAGTCCCTTCTGCTGCCTCCACAAGCCTTCCTCAGCT +GCCCTAGATGCTGCTCTACCCCTTTCCTCCAAGAAGGGAACCGCTTCTCCCCCAGCCTCC +CTGACAGTTCATCCCAGTGTCCCCAGAGCCCTCTCTGGCAGGAAGCTTGAAGTGCCTGAT +CACTCTCTTTCTGGTTTGCAGTTCAGCCTCACACCCTCTCACTCTGCCGTCTCTGCACTT +TGAGGACAGCTGCTCCCTGCTGACCTATGCAACCCATGTAGTTAGTGGCCTCTGAATGGA +AAGATGATTGGAAAGAGGCAGAATGGGAGCACACATCAATCTTGCTGGTTTGACAAGTGA +CATTCTTACAGGCAGATTCCTGCAGCGATGATGCTAGGAGAAAGAAACCTGATGCTTTGA +AATGCCATTGCTCTGAGAATGTGTATAAAGCTGTATGGATATACAACAATGCACACAAAC +TCCTACCCTGGCCTTTTCCTATGCACATGGTCACATTCCACAAGTGTCACCGATACCTTC +TCTCCTCGAGGGAGGTCAGAGCATGGGATAAATTGCCATTCTAAAATTGCTGATTTTAGC +CCTCGTTTGAATGGGCTACATGCCGTGGGGTCCAGTGGCCAAGGAAAACAACTGAGGTCT +CCCCAAGCACAGGATAAGCCTGATTCAGAAGCCATGGAGGGCAAGGGGAATTCTTCGCTG +GTGCAAAATTTCAATCGAACAGATGATGCTTTAAATCTGTGAGCCTTCTTTTGTGGGTCC +TTAGATCCTGGGAAGGAAATGAGTGACAGTCATGATCGGGGACACCTTGCTGCCCCGCTT +TACCCGTCCGTATTTGCTCAGGGCAATGTAGGTCCCTTGGTACAAGTCTGACTCGTAGGC +ATTGTAATTGTTGGGCAGGAGGGTTTCTCTGAACTTGCATTCTTCTTGGAAGCTGGGCTG +TGGAAGACATGGGCAAACAGCAGAGACTGGGTTACAAATGAGGAGTGCTGCAGATGCCAG +CTGGGCCGCAGAGAGTAGGCCCCTCTGCCAGGTGCCCTTCCCTTCTCTTTGTGAGACAAC +CACCGTGAGGTCTGAGCATCCTGGGTGAACAGAATGGTGAAAGGTTAGGATGGGAAGAGG +CTGCAGGCTCTCATGGTTTCCTCTCACCTTCCCTCCTTTACGATAAGGAAACCAAGGCCC +AGGGACACAGGGGATGGTCTGTGCCACATGGGGTAGAGCTGAGGCTCTACCACTCAGGTG +TCCTGACTTCCAGAGTAGTTTCTACTAAGTCCCTAGATGGTAACTTATTCCATTCAAAGA +ACAGACCAGGAAATGACACAAGCTGTTTTCTCAAGTCCACTCTGAGAGGGAGTCTACTGG +AGCAGGGATGAGAGCTCAGGGTGCTATTTCGTGACTTTTCTACTTCCTAATTGTGTGACC +TTGGGCAGGTTCCTCCCCTTGCAGCCTCAGTTCTCTTTTCTGCAGACTGTGTGTGGTGGG +GGAAGAAGGAGAGAGGCGGTTGGTGGAGGGGGAGGAGACACAAGTGATCTCTTAAGCCCT +TTCCAGCACTGCCTGTCTCTTTGTTTCTGCTTGTGGTTCCTCAGTCTGTCTTTCCTGGTT +TAAGTCTCAAGTTTTCTATCCCTCAAAAAGGCCCATTCTCAGTTTTGACTTTGAGTCTAG +AAGAGGTCTGGTACCTCCTAGACCAGGGGTCCCCGACCCCCAGGCTGCAGACCCATACCA +GTCAGCGGCCCATACCCGTGCGGGACCTGGGCTGTACAGCAGGAGGTGAGCGGTGGGTGA +GCGAAGCTTCATTTGTTTTCCAGCCACTCCCTATTGCCTGCAAGACCACCTGAGCTCCAC +CTCCTGTCAGATCAGCAGTGGCATTAGATTCTCATAGGAGCAAGAACCCTGTTGTGAACT +TTGCATGTGAGGGATCTGGGTTGCCTGCTCCTTCTGAGAATCTAACTAATGCCTGATGAT +CTGAGGTGGAACAGTTTCATCCCCAAACCGTCCCCCCATGTCCCCATCACTCACCCTGTC +CATGGAAATAGTCTTCCATGAAACTGGTCCCTGGTGCCAAAAAGGCTGGGGACTGCTGTC +CAAGACAATCATAGTTCTCCAGGGACATGCAGGAACAGAAATGGTGAGGAGCAGGAATTT +TTATGGGGAAAAGGACCTGGTTCCCAATGTGACAGGTGAGGCCAAGGAGCCTGGGACCAA +CAAAAAAATGGCCCTTTCCATGCTAATTTTGTAGAGTGTGTGTGGACCACCTGTTCAGAA +CATGAACGCTGGACTTCCTGTCACATGAACACTGGACTTCCTGTCACATGAACGCTGGAC +TTCCTGTCTCGCATGCACAGATTCATTCCCAGTACATCACCCCAAGTCCTCCTCTTTCCT +CTGCAACCTGCCTGGGTGGCTGCCCTAAGGGAGTATGCGGGGATTTCCTGCTCTTGTGGG +GAAGCAGCTGGGTCGGGGCTAGAAGAACAGAGAGCGAGGTGGGAGCCAGAGACCCGGGAT +CTACTCTTGAAAAGAAATATAGAATGAGAAATGGATGGAGGATAACTTCTGACTCCTTCT +TGCTTGAGTATAAAAAAAAACCCGCTCGATGGCTACTGGGCTGTGCCAGAGGTGTCCTCT +GACCTTCTGTAAAGGAATCGTACTGCTAGTGTCCCATCTTGCTGGCAGTGTAGCTGGACG +AGAACCTCTTGCTGTTCTGAAGGGCTGGTTAGTAGCTTGCTCCTCAGGGCCCCAAGACTC +CCAGAGCCCTTTCAGTGGACCTCTCTGGCAACATTTAGAACAGCCATACTTTCTTTCCCA +ATAGACTCCAAGATCCCTGAGATGAGGACTGTGTCTTGCTTGGTACATGATGCTGAGTGG +ATGGTGGTTTAATAGCGACAACATGGCTGGTTTCAGTGGCTCACACCTGTAATCCAGTAC +TTTGGGAGGCCAAGGCAGGAGGATCACTTGAGCCCAGGAGTTTGAGAGGAACCTAGGCAA +CATAGCAAGACCTTGTCTCTACAAAAGCTTAAAAAAAAAAAAAAGGCAGGTATGATGGCG +CATGCCTGTAGTCCCAGCTACTCTGGAGGCTGAGGTGGGAGAACCGCTTGAGGTCGAGGC +TGCAGTGAGCCATGATTGCTCCGCCGCACTCCAGCCTGGGTGACAGAGTGAGGCCCTGTC +TCAAGAATAAATAAATAAGTAAATAAGGACAGCACAGAAACATAAGGAGACCCCTGCATG +GGTGGCTCTTTCAATGTGATGTGAGCGTGGGTGAGGGGACAGCCTTGCCTATGGGAACAC +GGTGAAACTGCCCTCATATGTTTTCCCCATCTTCTTCTCTCATGCTTGCAGCTTATTTAC +AAAGCACTTTCACTGATGTTAACTTGCTTGAGATAAATGTGAAGGCGTTCACTAGCCATG +TCAACAGGTTAATGCCACACCGGGGGGTGGGTTTTTCATAAGCTTTCCTGTTTTCCTCGT +TAGGATGCTCAGTGAATATTTGTGGAATGGATGAATGAAGGGATGTCTTAAAGGTAAAAA +GGATGAACTAATCAATGTAGGTCAAGAACATATTTGTGCCACAGCTTTAAGGTTAGACTG +ATGACAATAGCCTCTTAGCTACGTGAGCCTGGGGAAATCATTTAACCTCTAAAGCTTCAA +TTCCCTCATCTGTGAAGTAAGAACAGTAAGAAAAATTGTGTCATAGAACTGGAGTAAGCA +TTAATTGAAATTATGCATGGAAAGTCCTGGGAACAATGCTTGCTATACAGTAGAATTAAA +AACAAATTAGTAGTACTAGTATTCTTCTCCAAGTAAATAATGAACTACTTTACATTAAAA +GCCTCGAAAGACTGCCTTACCCTGGATCACCAGTCCCATAAGACTTGCTGGGGGTTACTG +GACAATTTAGCTTTTAAGCTCTGCGGTTTTTGATGGAGTGCCTGGGAGACAGTAAGCTTG +CATGGAAGAGCAGGAAGCCAGAGGAAGGGCAGAGGCTGACGCTGGCTCTGAACCAAGACC +CCTCATTAGGAGCCTCTCTGGACCCTGGTTTCCTGCCCTGTGCACAGGACTTCAGTCGTT +GGTGGGCAAGCTTGGGAGCAGCAGCACCAGGAAAAATTCAGCTCAGAACTGATTGAAACA +TTCCAAGTAAAGCTACACTAATGAGAAGTCCAGTACAGGTCAATGAACAACATAGAGTCC +AGCAGTAGATCCCAACACATACATGGATGTAAAATGAAATTAATCTGAAATGAATATAAA +GTAAAAGTGTTATTTTAAATCACTAGAGAAAACATGGTGTTGGAACAACTGAATGGTATT +TTATTATAATGATAATAAAGTTTGATGTGTATGACTTTATCCCTTACATCAAAATAAATT +CCAAAGGGAGTAAAGATTCAAATGTAAAAAAAAAAGAACCATTAAAATCCAGAAAAAGTT +TTTTTTAATAAACTCAGAATCAGGAACATCTTTCTAATCAGGACAAAAAAAATTAAAACC +ATTTTTAAAAAGTAATAAATTGTCTTCTACTTGAAAAATATTACCTTAAAAGAAGAACAG +AAATGGTAAACTGGATGAAAATACATACAATACACATATGTCAAAGAATACATTTTGTTA +CTATATTCAGAACCCTAAACTCACTGGAGAATGAACAGCATTTATAAAACAGAAAATTCC +CAGGAAAAGAACTATCAATGGCATTTGAGCAGAAGAGAATATGCCTAATAAGAGAAATGT +AAGTTATAACTGTGAGATCCCATTTTTAGTGGCCAGATTTCAAAGAGAAAAGCGTTTGAC +ACTATGCTCTCATTAGTGAGGGCACAGAAACTAGGAATTCTCATTTAATGTCCTCTGATG +TGTATACTGTTATAATCTCTATAAAGAGCAATTTGGCAGCATCTACCAGAATAAAGGATG +AATATAGCAACTGATCAGCAATTCCACTCCTAGAAATTTATCTTACTGATATATTCCCAC +ACACGCACAAAAGTTACTACAGCATTAAATAACAAAAGACCAAAAACAATGTATCTATTA +AGAGAGGAGTAGCTGAGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGTG +GGTGGATCACGAGGTCAGGAGATTGAGACCATCCTGGTCAACATGGTGAAACCGCATCTC +TACCAAAATACAAAAAATTAGCTGGGCATGGTGGTGCATGCCTGTAGTCCCAGCTACTTG +GGAGGCTAAGGCAGGGGAATCTCTTGGACCGGGGAGGTGGAGATTGCAGTGGGCCAAGAC +CGCACTCCAGCCTGGTGACAGAGCGAGACTCTATCTCAAAAAAAAAAAAAAAAAAAAAAA +AAAAGAGGAGTAACTAACTCAATTATGGTAGATCCACATGATGGAATTCTATAAGCCTTG +AAAAGATAAGAAGCCTCTCTGTAATGACATGAAATGGCCTCAAAGATACATTGCTAAGTG +AAGACACAAGGTTTGAAAAAGTGTTGGCATAGTACGCTCTTGTTTGTGTGATTTTTTAAA +AAAGATGATACCGGTGCGTGCACGTGTGCGTTAGCTATTTCTGGAACGATATACTGGAAT +GAAACACTGGTAACTGGGGCTGCCTCTAGGGAGGAACTCAGTGGCTTCAAGACAATGGTG +GGAGTGAGACTTTCCATAGAATATTCTTTGATACTTTTTTCTCCTTAAAACATGTTCCTG +TGTTACCTAGTCAAGTACGTAAATTATTTAAAGTGGGAAGGGAATTTAGGGTAGCAAATG +GGCCAGGAAACGAAGCGAGAAAACATTTTGATCAGAAACTGGTGGTCTCCTTCTTGTTGG +GTCACGGCCCCTCTCCACCCACCAGCCTCCCCCCTGTTCTAACTTTGTATGTCCCTGGAG +AGTAACCCGCCCAGTCAGTTCCAGAGAATTTATTTCTGATCTGGATGGTGGTTAAGGGAG +AGGTTTCGTGTGTTGTTTGCAAGCTCTAGTGAGGAAATGAAATCTTGAGGTGGAGGAAGG +GGAAGTGGGAGGAACTGAGTGACTTGGACAAGAAACTCTCAAGCCATTGCCCACTTCCCC +GTGCCTAGAATGTGCCCATTTGAGAACCCAGCCTCTCCTAAACATCTGGATCTCCTAAAA +CATGATTGTTTAAGCATGCATGACCATGGATGCGTAGATTGTACTTTGCTTCTCTGGTCA +TTCGATTTTGGATCATTCAAATCCACTCCCCCTCAACATACACACTTTTTTTTTTTCTGT +TTCTATTTTTTTTTCAAGTTTACTACTTTTTTTTCTTTCCATTCTGCCCTTTTCTCTAGC +CTGTCTCATATCCCTGGCCTTCCCCAGAATCCTGTACAAAACTAAAGTGAAAAAAGACAA +CTAGTAGAGGAAGCTTGTGTTAGAAGCCCTAACCTTCCCCTTGCTGCTCTCTCTCCTCCG +CCCTCAGCACCCACATCTGTGGGGTTTGGAAGGCCAGGAGGCCTGTGGCATGAAGGAGAG +ATAGTGCATTTTTTCTGAATGCTTCAGGCTGATGGGATTTTCCCGATGCCCAGAGTGATG +CTCAAGACCCAGCCCCTTAATTCATCTTCATCAGAGCCCTGAGCTTTGAGTTCTCATGGC +TTGGGAATGTTGGCCCCTCAGCTCTGGTGAAGAACGCACTCGAGCCAAGTGAACGCCATG +TTCATAAAAGCAGCTACTGTATATGATTACTTGAATAAATGAAAATCATTCCACTGGGTC +ACATTTCCTGGGCCTGCCAGGCTCAAGCCCCAGCATGAAAATATCTTCAATTTGATGTAG +GTCTATTCAGACTTATGTGCATTTGGCACTCACTATGGAGAAGGGCATTTCTCAGAGGAG +CAAGCATATCCATGGGGTAGAGGTGCCTCCAAAGTGTGAGGTGGACAAGACAGCCACCCT +CTCGCCTTTAGAGCTAAGTCACTTGGACCAACGAGGATCTAATCCTGCTTTTAAACATCT +TCACCCTGTGACCGCTGGGGCCATTTGTCCCTGTTCCTCCTGGCAGTGTGTGTTGGATGG +AGAAGGATGGGGTGGAAGGATGTGGGCAAGAAGGAAAAATAAACCAATTCTTTGTCCTAA +GACTTTCTTCTGTAGCCCCTGACTGCTTCTTTTCCTGTCTTTAGCTGAAATATCATCAGC +TCTGAAGATGCCTGCATTTTCCAACCCTTTTTCCTAGCACACAATTGAACTGTTGATTTA +GGAATGTTGGAAAGTGTTTTCATCAGGTGTTTCATTCTTCTCACTCCAGTGCAGCTCTTT +GTAGCAGGCGGGGATTTGTATGCAGAGCCTCAGGCCCTGCATAAGGGCATGCACCTCCCG +CTGCTCTCCAGCCCCATCTCCCAGCACTTCCTCATGGTGGGTGTCCTTCATCCCATTCCC +TCAGGAGTGCTGTTTTCTGCTACAGTGGCAGCTGAGCCAAGGCAAGGCTGGTCCTCCCAG +CCTTGTAATGCCCCAGATAATAATGTAATGCCCCAGATAATAATGCAATGCCCCAGATAA +TAATGCCCCAATGTAATGCCCCAGATAATAATCAAAGGTCTCTGGAGGAAATCAATTTTG +TCCTTTGCACATTGTCATACTGTTGACGAAAAGCATGTAAATGCGGCTCTTCTTAGTAAA +ACTGAAATCACTTGAAAGCACGACCGAATTGCTGGTATCTTTTTACTAGTATATATTTTT +CTCAACCAAAGGATTCTAATAGAACCACTGTCAGGTGGAGATCCTTGATATTTTGTTTTC +TGAATTTCAAAGGGGACCAAGGGGGCTAGAATTCACTGATTTCTGCCTCATCCTCAGAGA +GCAGAGATCCAGGCCCAGAGAAGTTCAGTGACGTTGCCCAAAGTAAGACGAGTAGCTGGA +GGGTAGGTTGGCCAGGAACTGGAACTCGGGTCGCGGAGCCCTGAGACGGGGCTGCACACA +GCTGTGGCTGGACGTGTGACCCTGGAGACCGGGTGTCCGCAGCTGCACAGGGAGGATGAA +GATCAAATGCACCTCCTAGGGGTGCTGTGAGATCATGCTCGTGAAGCCCTCTGCAGCCTG +TGAATCCGAGCACAAGCAGTAGGCTAGTGCTCAGGGCAGGGCAGCTGTTTATATTGTCTA +AAGGGGGGCCTGGCAAACTGCCCTGAGCCTCCACACCCCTCTTTCCAGGAGACAGACATG +TGTGAAGCCACTTCTAGCCAGGTTTCCTTGGCCCTTGTTCTCTGCCCACGAGTCGTTGCC +TTGTCCCCCTCACCAACACCTCAGCCCCAGCCCAGTTTCCCTCCCCCACCCATGAGAAAT +CCCATGAACTGGCAGTAGCAGCTGAGCCTGGGAGATGAGGCAGCTCCGGGGGCTTAAAAG +GAAATAGTGTGAATGAAATCATCACCCAGCAGGAGTCTTCCTGGCTCCGGGGATCAGTTG +GCAATTGTTTTTTTAGACTGTGATAACGGCCTCTGAGGGGCGGAGAGGGAGGGGTAGAAG +TTGCTCAGGAGCATCTGGTCCTGAGCCACACAAAACGTCAGGTGCCCCAGGCTTGGGGCA +CAGCTGTCCAGCCCCACTCTCTGTGTGCAGGCCCGGCTGGCCCTGAGGTCCAGGGAGGAG +AATCTCCCTCCCTGGAGAAGATGCTCTTTGGCCAAATGCTACTGAGGGTGAAGGTAGGAG +GGGTGGGAGGGTGGAGGTGAAGGGCGCCGGGTCTTTTCCCAGAAGTCTTCCTTTCTCCTG +GACTCTGCTTGTTTAGTAAGCCCAGCAGTTCATCAACCTGCCTAACCCCCTTTGAAGTCA +TCAGCCAGTAACGGTGCTGCAGAGTGAGGGCTGGGGGTGGGGTGGTGGGTTTCAGGCATT +AGGAGTCAGCCTCCTTTCCTTTTTGCTATTCTGAATGCTCTTCCCCGCTTTGTGGCGCTT +TCTCTGATGGTTAAATCGTATATTCCCTTCCCGAGCCTTTCCCAGCTTCTCCTTCCAGGG +CCAAGAGATTGAAAGTGGGAAGTGGGTAAATTTCCTCTATATTTGTGCATTTTCTCCTCC +CCACAATTAAATTCCTTTCTGGGTAGGAAGAAAAAAGTAATAAATGGTTTGTTGATAAAG +GCGACAAGGAGAAAGAAGAGTTTATGAAATTTGTGCTTTCTCCCAGGAGATTTACTTGCT +AAAACGTCCCTTGCTTGCATGGAGTCCCACAGCCAACAGCCTAAATTCCCGGCTCTCCCG +ACCCTATGGGCTTCCGGGCATTATGCAGGCTGGGAAGAAGGGGTTCTTTGGGATGCCCCA +CCCTACAGAGGGGAAACCTGCTCCATCAAAACCTGGGTTGGTCCCAGGCCTCTTCCTGTC +CTCGCCATCACTTTCCCAGAGAGCGGTAACAAGGATATGTCTCTTCTGTCTCATCTCACT +CGCCCTCCAGCTTTCAGGTTCAGTGTAACATGGGGAGTGGGTGGTCCCCTGCCCTCCAGA +GGCCATGTAGCCTGCTGACCCCCAAGCCTGCCTGTTCCTCAGAAACACCTGGCAAATTTA +AAATACAAAAACAAATGGATTTCCAGGCCCACACGCCAGCTCTGCTGAATAAGAATCTCC +TAGGTAGGTACCTGGAAATCCATACTTTTAATAAGTTTCCAAGGTGACAGAGATGCAAAC +TGTCCACAGACCCGTGTGGGAGACCCACTGATTGTAGTGCATGCCGTATGTCCACATAAA +CCAACCCAGACTGAGAGATGTTAGCACTAAAGATTATGGGGTGGAGGCCACCTGGTGAAC +CCGTTCTTGTATTTCATAGACCTCCTCTGTTGGGACAGCTCCCCTGGGACCCAGTGCCAG +TCCTGGATCTATTTCTTCACATCCCAGTCCTCAGTTTATCCTCCAAGGGGCAGTAGATCA +GCTCTCCACACCCTCCCCATAAATAACTTTGATATTTTTTGAGGCCTGCTCTGAGGTCTT +CCTTTTTAGCTTGCTTATTTCTGTCAAAGGAACTCTCCATTTCTTCAGCCTCATCGGGAT +GTTTGCCCCGCCATATTTTGGAATAAGCCAAATGATGGGCCGAGGGCTGCAGGAAAGAGT +AGGTCAGTGAGAGCAGAGGTTTTCGTCAATGTGCTTAGAAGCTGGTTGCATTAACCCAAG +TGCCAGCATTGGCACTCCCAGAGGTGACCTATGGGGGTGGGGATGGGAATGGGTGGGACT +GGTACCAGCCTAAAGTGTATAACGGGTAGGCTGCTTCTCTAGCGTACGTGATCGGAGACC +AGAGGATTGAAAACCCTAGTGCAGAATCTCAGCACACTGATGAGGATGAAAATAGCCTCC +CATTCCACTCCTCCTGCTGCGCACGAGGCTGGGGCATCTTGCAGGGCGCGTGTCATGGAG +CAGCGCACCCAGGCAGAGAGACAGACTTGCTCTCGGGGCCTCGCCAGTGCAGGGAATCAC +ACCTGCTCACAAGCCTGGATGCCAGAATGTGGGTTTCCCTCTGGCCCACGGGCTCCCTGA +GCTGTGGTTTCCGTTTAAGCACACGGGCTCCGGCCGGCAGGTGGGAACAGAAGAAGCACG +GGCCAGGGCAGAGGACAATCACCCGTGAGGCTGAAGAAGCACAAGCTGCAAGGCCCCTCC +CTTTCACAGGCTCCTCTCACAGCCTTTCCTTTCCCATTTAGATAGTCACTTCTCTACTCA +GGACTTCATATTATTTTCTTCAACTGTGTAAGCATCAAGCCTTGTAAACCTGGCACTTCC +CCGGCCTGGTGAACTCACCGTTGCGTACAATCTTCCTTTACTGTTCATGGCAACGAAGAG +GGCACTTCTCACTCCAAAGAGACTCACCACGCCTCGCTCCACAGTGGAAATTTCCAGCAG +GCCTGACAAGGAAAGGGGGGCCACATTACCTAAGGCTTGTGCAAATCAGAGTGGGAACTT +GAGCCGACAAGGGCATCTCAGTCCATCCCCCTTCTCCTAGAAAGCCAGACTCTCCATTGC +CCCATCCATGATCCCTCTAACTCTAGGAGACCCTGGCTGCTGGACTCATCGAGTGCTGCC +ATTGTGCTGTTAGAAATCCAGTTCTGCAAGGGAAGGTTCTGATAGCAGAGTTAGGGGCTG +CAGTGACCACTTAGCTATCTGTTTAAGATGAGCTTTGAATCTGGGCTTTCAGTGACATAA +TTACTTGAGGTCCTTGACTTGAGTAAAAAAATAAATTCTGATTCTTCTTCTTCTTCTTAA +TGTGTACTCTACATGTTTCAACAAATCTCAACCCACTTAATCTTGAAAACACAGCAGCCA +CACCATAGCTGATGGCTTTCTTGGATCCTGCAGCCCCCATCCTTTCTTGGATAGGAGACT +AACCATACAGCAAGCTGGCAGCTTGCAGGCAGCTTGCAGGATAAGAACCTGGGGACAGAG +GGAGCCGCTGAAATAAAAAGAAGGATGTGCTTCAGTTGGACATTTTGCAATTGAATTTCC +CTTCCTTCTCCAAGAAAGAAGCTGAATAAAAATGAGCTTGTGTCAAATTTGATCCAAGTA +TACTAACTGATTCTCCCTACCCAGGCCTTGGGGGCTTCCCAGACTAATGGTTCCTAATGG +TCTTACAAGGCATCAGATGGGCCAGTAATGCTGAAATAGTTAGTGCCACTGAGGATCTAA +CCAAGGCGATGGCAAAGAACACCAGGATGCTTGGACCGCAGTATATTGAGCTTGCACCCA +GGCAGGGTCACGTGGAATCATCTAAGTGGTGAGCAGCATTTCTGCCCCCTTTATCGTGCA +TCCTGTCCGCTAGAGCAGGGCCCCTTCACCTTTTAGCCCTGCATGAGCCCAAACCCCCAA +GCGTCCCGACTGGCTGCAGCTGGCACTCACTGTAGGGGTTCTCCTCGTGGGTCCCGCTGA +TCCGGCCGTCGGGGAGCACCTGGAGGTGAAAGCCGATGCCCACGTTGCAGTAGAGCCTCC +GCTGCCGCTTGATCCCCACCAAATAGCCACTTTCCCAGTTCACCCCGGCAATCTCTCCAG +CTAGCCCGGCGCGAGACCTGGACAGCAGGGTGCCCCAGCCCCTCGAGTCCAGCAGCGTGT +TGTTGGCACGGGTGCCTGCAGGCGAGGGCACCACCATGCCCACTAGGATGCCTAGGAAGA +CGAGAGCCCACAGCGTGCCCTGCAGACGTCCTGCTCCCCGGGACATAGTGATGAACAGTT +TCTGTCCCAGGGCCATCCACCTTGCCTCTCAGGCACGTGGTCAGAATTAATGGCCCTAAA diff --git a/test/csq/ENST00000543077/ENST00000543077.fa.fai b/test/csq/ENST00000543077/ENST00000543077.fa.fai new file mode 100644 index 0000000..41582c0 --- /dev/null +++ b/test/csq/ENST00000543077/ENST00000543077.fa.fai @@ -0,0 +1 @@ +12 17460 23 60 61 diff --git a/test/csq/ENST00000543077/ENST00000543077.gff b/test/csq/ENST00000543077/ENST00000543077.gff new file mode 100644 index 0000000..6ce67db --- /dev/null +++ b/test/csq/ENST00000543077/ENST00000543077.gff @@ -0,0 +1,7 @@ +12 ensembl_havana gene 1 17460 . - . ID=gene:ENSG00000111241;Name=FGF6;biotype=protein_coding;description=fibroblast growth factor 6 [Source:HGNC Symbol%3BAcc:3684];gene_id=ENSG00000111241;logic_name=ensembl_havana_gene;version=2 +12 ensembl_havana transcript 2 16065 . - . ID=transcript:ENST00000543077;Parent=gene:ENSG00000111241;Name=FGF6-002;biotype=protein_coding;havana_transcript=OTTHUMT00000398938;havana_version=1;transcript_id=ENST00000543077;version=1 +12 havana three_prime_UTR 2 240 . - . Parent=transcript:ENST00000543077 +12 havana exon 2 249 . - . Parent=transcript:ENST00000543077;Name=ENSE00002242290;constitutive=0;ensembl_end_phase=-1;ensembl_phase=0;exon_id=ENSE00002242290;rank=2;version=1 +12 havana CDS 241 249 . - 0 ID=CDS:ENSP00000445479;Parent=transcript:ENST00000543077;protein_id=ENSP00000445479 +12 havana exon 15979 16065 . - . Parent=transcript:ENST00000543077;Name=ENSE00002260911;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00002260911;rank=1;version=1 +12 havana CDS 15979 16065 . - 0 ID=CDS:ENSP00000445479;Parent=transcript:ENST00000543077;protein_id=ENSP00000445479 diff --git a/test/csq/ENST00000543077/not-a-start-lost.txt b/test/csq/ENST00000543077/not-a-start-lost.txt new file mode 100644 index 0000000..bedf4a0 --- /dev/null +++ b/test/csq/ENST00000543077/not-a-start-lost.txt @@ -0,0 +1,3 @@ +16063 A G synonymous|FGF6|ENST00000543077|protein_coding|-|1T|16063A>G +16063 A G synonymous|FGF6|ENST00000543077|protein_coding|-|1T|16063A>G + diff --git a/test/csq/ENST00000543077/not-a-start-lost.txt-l b/test/csq/ENST00000543077/not-a-start-lost.txt-l new file mode 100644 index 0000000..bedf4a0 --- /dev/null +++ b/test/csq/ENST00000543077/not-a-start-lost.txt-l @@ -0,0 +1,3 @@ +16063 A G synonymous|FGF6|ENST00000543077|protein_coding|-|1T|16063A>G +16063 A G synonymous|FGF6|ENST00000543077|protein_coding|-|1T|16063A>G + diff --git a/test/csq/ENST00000543077/not-a-start-lost.vcf b/test/csq/ENST00000543077/not-a-start-lost.vcf new file mode 100644 index 0000000..ed04add --- /dev/null +++ b/test/csq/ENST00000543077/not-a-start-lost.vcf @@ -0,0 +1,6 @@ +##fileformat=VCFv4.2 +##contig= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO +12 16063 . A G . . EXP=synonymous|FGF6|ENST00000543077|protein_coding|-|1T|16063A>G;type=ENST00000543077:4553383-A-G diff --git a/test/csq/ENST00000545279/ENST00000545279.fa b/test/csq/ENST00000545279/ENST00000545279.fa new file mode 100644 index 0000000..d09a7e0 --- /dev/null +++ b/test/csq/ENST00000545279/ENST00000545279.fa @@ -0,0 +1,934 @@ +>5 5:135468514-135524455 +TCCCTCTCCCTCCCTCCCTCATCCGGGTCCTGGGCGAGCGGGCGCCGTGCGCGTGTCCCG +CGGCCGAGCTGCTAATAAAGTTGCAGCGAGGAGAAGCGCAGCGACGGCGTCGGGAGAGCG +CGCCTAGCCGGCTCGCGAGTGAGTGAGGGTCCCCGGCGCGCGCGGGCGAGGGGAACTGGG +GGCTGCAGGCTCTGCCCCGGCGGACTCGGGCCGAGGCGGGGGCGTTCGGCCGCGGACGGA +GCGGAAACGACCCAGGGCCTGTCGGGCGGGAGGTAGGCCGAGTCCTGGCCTGCCGGGGTC +CCGGCTGGCGGACACGGTGCGGCCCAGCGGCTGCGGAGGCCTCGCTGGCTGCCCGGGGCG +TCCTGAGGCGGGGCCGGGGCTGGCCCTCGTCCCAGCCCCGCTGTTACCGCCCAGACTTTG +GAGGGAGGCGTCTGGGACGCCCTGGAGGGGACCCCCTGACCCCGCGCTGTCCTGGGGAGC +GGTTTGCTTTCCTAACTCATCGGATGTACCACCCTGGATACACACCCTTGATAGGACTGC +GGTGCTCGGCCGGGCAGCCTGGGCTGCTGCACTGCGAAGCTGTCCAATGGCTTGATGAAT +CCGTGCCGCCGTCGCTTTGTGTTTCAAAGATAAGGATCCGCGCTTATCGGTGGGAATTAC +ACTCTGGGCAGTTGTGACCGGCTACTGCAATCAGCTGGTAGTTAGACCTGGTTTCTGCCA +CTTGCCATGTCAGTTTTCACCACTGCAAGGATTTCTTCTACTTCATGTAAACTTCTCTGT +GCTGCAAAGAGAATGCCAAAGCAGCGTCTTTTTGCCTTCACCATATTCAGCCGCTGGCCG +GGTCCTATACTTCAATATCAGGGCTCAAATTAATATTCCAGTCTCTTCCCCTCCCCTTTT +CCCCTCTCCTCCTTTCAGCTGCTGTTACTACGTGGAGTTTGGAGCCTAAGCTTTGAAAAC +TCCCATGTGGCGCGCCCGTCTTAAGTCTGAGCATGCTCAGTAGCCAAAACAGATTTTTGG +TTGCAGAACTCGGGCGAGGATACTTGGGGTATTTGGACGTTTGCCGGCTTCCCAACAGAA +TGTTCCGGTTCTGGTGGTGATGGCATTGGAGAATGGGGCTTAGGCAAGCCTGTAGGTGAG +GAATGGCTGAACACCCTGAGCCAGATGTTTATCTTGATTGTAAAGACAATGTTTCCTGAC +CAGCTGGAGCTTTGGGGGGGGGGGGGGGGTGTTGCGGGGGGAGGGAGCAATTTTGGTTGC +TTGTGCATTTAAATGGGTGTGGCGCTAAGTATATCTTGTTTACCTTATCTTTCTGTGGAA +AAGTTTTGATGTCTAGGTTTGTCACATCATGCCTGTTGCCTAGCACTACCAAAAGGGTTG +TTATCTAGCAGCAAAGATTGAATAGGTGGAGGTCGTGGCTTGGCCTCACAGAAGTTGAGA +GGAAAGGGTACTTGGGTTGCGTTTTTGAAAATTCGTATTTAAAACTAGAGTACTTGAATT +TCCTTAGAGTACCTGAATTGCCCAGAGTGAATTAGTTTTTAATTTTAATTTGAAAGACAA +AAGATTGAAAACCTTAGTCCCAGTAGGTTTAGTAACATTCCAAATAGCTTACAATTTCTG +CTAGATGCCAATGCAGTAGTATCCATTGTGGGGAAAACAGTACCTACATTCAGTGTGACA +GTTTCACATTTATGGATCCAAATATCATTATGAAATTAGTGTTCCAAATTTAAGGAGCTA +TTTGCAGATGTATAACAAATTATTTTAGTCTTTTATTCCTTTGGTAACTATTAATATTTT +TTTCTCTACAGTGAAAATTGTAAAAATGCAAAACTTAGACAATTTAACAAAACTTAACCT +TCATAAAGGTTGTAGATACTATGTTTAGATTTATAAAGTTTAATTTTGATGATTATTTGT +GTGATTGTTCCTATACAGCTTCCTTTCCTTCCCTTTCCACATTGTTGCTCCCTCAGTCTT +TTTTACATTACTGCTGTTAATTTACCCATGTATCTTTGTTAAAAATACCTTATTCATCAT +TTTGTGCTTCCATTCCTTTCAGATCATAGCTGAAATAAGCAAGAAAAGTTAGATTAACCT +TCTCAACTGACTTTACTCTCAGGTTTTAAAGGCATCCACATGATATGGTCTAGTTAAAAG +GAGGAAGAGAGCAGCAAACTGGAAAAAAAGAATAAAATATTTTCGTAGGTTCTGTACAGA +TCTGGTAGTATTATCTGCGTGTCTGGTTCACTGTGGTAGGCGCCACAGAAATGGGTAGAT +TGATAATGTGTTGGATTTCTTTCCCCTCTGGCAAAGTCAGCTATTAATTTCAGTGGGAGA +CAGTGGCAGAATGTTGTTACTAATGAGGTTTGAATCAGATTGTTGTTTACTGTTGGTTAT +GTAACATGTTGCTGGGAGTATTATTAAAAGTTGCATTCTGCAGCAAAGTAGAGGCAAGTA +AATTCTGCTTACCCTCTTCACTGGGTTTTAATTCTTGGCTGAACCTGAAGGCACATTAGA +TTACAACCATAATTATACCTGGGCAGCCTGTCTGTTTCCTGTTTTCATCATGAACCCAAA +CATTATGATTTGCAGTGATGATCTTTTTTGTCCTTTGCATTGAACGGAGGCAGTGTGTTT +TCTCCCTCTACTGAAAACAGATTTGTAACTTGGTCAAATTAAAGATTTTAGTGTTTTGAA +AACTAGGCAGTAAAATACCAGTTTTTCATTTCTTAATACAGTTACTTAAGTTGAAATACC +ATCTAAAAAAATCTATTTCATATATATTCTTTGTCTTTATGTAAATTTTAATATTACTAG +TACTTTGTAGAGTTAAAGAAACTCTTTTTGTTTATGACATATCAGTGTTTATTATTACCA +GATGTATATGTTGGTCTAGGCAATGAGCCACACATCTGGGTGAATTTCAGAGCTGACTTG +AGTACGCTTGAGGATATAGGTGTCTATTCTCTTGGTTTATCAGTCTTCCCTGTTTTTACT +TCTAGACGATCTATATTCCTTGTATCTGTCTGTCTGTCTCTCTGTCTCTCTGTACACTAA +CCACAAAGAAGGCAAATAGTTTATTTCTTCAAATGTTACAAGCAGCTTATAGCCTATGAT +TTGCCCGTCTTCTCATAGGGTCAAAGACATTGAGTAAGATTCCCTTTTATAAGGGATACT +AGTAGCCTGAGGAATGATTCTTGTCTCCACCAGTCTGGATATTCTAGAGAAAAGAATACC +TGGATATTCTAGAGAAAAGAATATTCTAGAGAAAAGAAAAGGCCCAAGGAAGCTGGGATG +CAATATAGGGTGCTTTCCCATCAAAACAGATGATGAAGGACCCTTGGAAGCTGACCCATG +GCATCCCCCCGCCACTGGGTTCTAGCTCTGTCGCCCAATCTGGAGTCCAGTGGCGCAATC +TTGGCTCACTGCAACCTCCGCCTCCCGGGTTGAAGCAATTCTCCTGCCTCAGCCTCCCAA +GTAGCTGGGATTACAGGCACCCACCACCATACCCGGCTAATTTTTGTATTTTTAGTAGAG +ACGGTGTTTCACCATGTTCGCCAGGCTGGTCTTGAACTCTTAACATACCTTGTTTTTCCA +CTTCTGAAGTTAATAGAATAATAGTCATTGGAATTTGCAGTTCATTGGTGTTGTCACATA +CCCTTTACCTCTAATCAGAAGTCTGAATCTGAGAAGTTTGTTTACTAAATGGGAGGTAAA +GATTTAGAACTCTTTTGGAAGAATTGTTAAAAACTAGATTGTTGTTAGGACTAATCTCAT +AGGCCACCTTAATATTCTAACAGCTTTGTTGTTTTCCAACCTGGAAAGATGGGGTAATTA +CAGAGTTCTTAGGTTTTTCATAAATAATCAGCTAGTTCTGGGCTATTTATTTGAGAGTGT +CTCTCTCTGTCGCCCAGGCTGGGGTTCAGTGACGCGATCTTGACTCACTGCAATTCTGCC +TCCCGGCTTCAAGCGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGCACCC +ACCACCACGTCCAGCTCATTTTTTGAATTTTTAATAGAGATGGAGTTTCACCTCGTTGGC +CAGGCTGGTCTCGAACTTCTGACCTCAAGTGATCTGCCCGCTATGGCCTCCCAAAGTGCT +GGGATTACAGGTGTGAGCCACCGTGCCTGGCTGGGCTCTTTATTTAGTTTTGATTTTTTT +TTTTTTTTTTTTTGCCTTGGGCAGCTAGGGGGGATGTTTTTGGCCCAGTTCTAGTAGAGT +GGTGTTTTCAGTGACTTTTCTTCCTCCTTTTACTGTATCCTACCTTGGTTGAGATGATAT +TTTGCAAGAAAGAGTTCTTTATTAAGTCAGTTCTGTGTGTGCAATACTATAATTGTAATT +CACTTTTGGAAGCTAGTTATTAACATAACATTTTGTAACTAGGTTTTGCTCTTGAATTTT +TTGGGACCCCCCCCCGCATCTCTTCCTATAGCATATATGTACTTTATAGACTGGTACAAT +ATAGAAGTTTGAAAGTGATTTGACCTGTTAAGATTTTAGCAGGATTTTTTCTTTTGATAT +CCATATATGTTGTTTTGTTATACCGAAAATAATAGAAAAAAACTAGTGTCCCATTCCCAC +TTTTTCTCTGAGCATAGCAACTGGAGTCTTGGGAGGAGGCTTACATCTTTCAAATTTAAC +TATGATCTCAGAATATGGCTGGTGCTTTCAAGGCAAGTTTTGTTTTGTTCAGGTTTGTTT +TCATGATGTGTTAGGATCTGCCTAGTATCCTATCTGGTAGGCTGTACAACTTGAGTTCTA +GTTATTCTGGTTTGTGTGTTCCCAGGAAGAGGGGGGTTCTGCAAAAATATTTAAAAGCCA +GTCTTCTTCTGTTTTCTTCTTAGTCACATCTTCTGTCTACTTTACTCATTGACCATTTCT +CATTCTTTGGAGATGAAAGTGTAAATTAAGTGAATGATGACACTAGAGCTGAAAAGTTAC +CCAGAGTCATGTTTATTCCCTTTTCTACTAAGCAGGGAACTTGAACTCTGGGTGCACATG +AGTTCTCTGGAGAACATCTTCATAATGCACTGTAATATATGTCGTGTACACAGGTTAGCT +CTTTGTGCTCCAGAGACACATTTTACAGTCATGATTTGGTATCTGCACTTGATGATTTTA +TAATTTAAAGGAATCACTACAAAGATTGACCAGCTCTGTGTCTGTTCCTGTGCCTACACG +CCTGTACAAGCATACTCAAACACATCTGGTAGCAATGTAGGAAATCTTGCAGGCTCTGTG +GGGGTGAGTGATACATTTAGATCAGGCTCTGTTTAATTAGGGGACTTAGAGGAGCAGGTG +AAGCTTAAAGAGTGATTAAAAACTGGGAAACAAAAGTCTGGCTGTGGGAGATAATAAAGT +AGAGAATTCTGTGGGCACAGAATAGGCAAGAAGATTATGCAGTGAGAAGTGTTGGGAATC +ATGAGTTCAGCTCCTGAAGGGCTTTGAAATCTGCTATGAGAACTTCTTATGTCTTTGGAA +ATCGGGAGCCACAGTTGAGGAAAGTGGTGATTTAAATGTTTCTCTGTGAAAATAATTTTG +GCGCCCATGTAATTGTATCCTGTCTTTCTTGTAGATGTTCTTATAAAGAATAGGATTTCT +GAATCTAGAAGAGCTGTGAGCAAACATGCTTTTGGTTTCCTTCTCCTCTCTGCGTGCAGT +TGTGAATGTGGCTTACAAAGTTGATAGCAGTTGTATACATGGATCTAGGGATGGTTTGAC +AGTGGTGGTGGTGGTTGTCTACTTGCTGACACTTGGTGACTACTATTGATAATGAGAACC +ACAAGGGTAAGAGATTTTTAAAGCTTTACCCCCACATCCCCCCTGCCCCCAAAAGTTACC +CTTAGGTTGTATGTATGCAAGTGTCTTTCTTCCATTGCAGGAGATCCTGAGCACCTTGGT +TCCCAAGCCTCCTGCATGGTCCGAGATTCTTGTTAAAAATGTGGGCAGTAAGGCCCTTCT +GCCAAGCTTAGTGAATCTGAATTTTGAGGGATGGTTCTAAGGAATTTGTTGATTTAAAAA +CCCCATGTCCAATTATTTTGTACAGGTTTGAATTAGAATACAATGGGTTGTGACCCATTA +TGGGCATTTATTTTCATGGGATGATGTGCTCAGGAGATTTTGTTTTGGCCAATAGTGTTG +AGGAAAATGTGGGGATTGGTTTGCTTGCCTTTTTATTTCAGATTGCAGCAGTCATAGAGA +TGTTGGAGCACAAAGTGAAAGAGTTGTTTCTGTGAATTCACTTTAGAAATCTAGCTGTGA +GCTCTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTCTTTCTGTATGTTTTTCTGTATGTA +TGTGTGTCTCGGGGTGGGTATTGAAGTCAGTTTGTGTGTGTGTTTATTATGAAAGTTGGT +CAGGATGTAGTACTTCCATAACCTTAGGTAAGAACAGGACCTTTGGGTTATTGATTCAAC +ATGAATTCATTTGAAATAGAAGCTTTGTGAAGCTTAGCAACATTTTATTCATATGGTTAA +TGTGTATAAAACTTAACCCTGAATCTTCCTTTAGCTTTCTTATCTGCATTTGCCAAATCA +GTTGATGTCAAACCCCATTCTTCCAGTTGTCCAGGCTGATACCTTGGAATCATTGTTAAC +TCCTTTGTTCTCATACACCCCATGATCTCCTTCATCAGGAAGCTTACTGTCTTTCATATG +TCTGCTGCTCACCACCCCACTGCTATCACCCTGGTTGTAAGCCATCGTCATCTTCTCCCC +TCCCTTAGATTACTGCATCTCTGAACTGGTCTCGCTGCTTTTATCATTGCTGTCCACCCC +TCCTCCTGCTTATTCTCAACATACCAGCCAGGATTTATTTATTTATTTTGAGACGGAGTC +TTGTGCTGTCACCCAGGCTGGAGTGCAGTGGCATGATCTTGGCTCACTGCTACCTTGACC +TCTTGGGCTCAAGTGATCCTCCCACCTCAGCCTCCTAAGTAGATGGGATCACAGGCATGT +GCCACTGCACCTGGCTAATTTTTTAATTAAAAACAATTTTTTTTTGTAGAGATGGAGTTT +TAAAAACTATGTTGCCCAGGCTAGGCTTGAACCGCTGAGCTCAAGTGATTCTCCTGCCTT +GGCCTTCCAAAGTACTGGGATTACAGGCATGAGCCACCACGCCTGGCCCAGGATAACTCT +TTTTTTTTTTTTTTTTGAGATGAAGTCTAGCTTTGTTGGCCAGGCTAGAGTGCAGTGGTA +TGATCTTGGCTCACTGCAACCTCTGCCTCCCGGGCTCAAGCAATTCTCCTTCCTCAGCCT +CCCAAGTAGCTGGAATTACAGGCACATGCCACCACACCCAGCTAATTTTTGTATTTTTCG +TAGAGACGGGGTTTCACCATGTTCGCCAGGCTGGTCTTGAACTCCTGACCTCAGGTAATT +TGCCCACCTCGGCCCAGGATAATTCTTTAATAGTGTAAGTCGAGAACTATCATGTCTGTG +CTCAGAGCTCTCCACTGAGTTCACAGTTTCCTTAGAGTACTGTAAAAGCTAAAGCCTTTA +TATCCAGCATGGCCATTCTGGCTCTCTGGTATCTCTTTGACCCCACTCCTTACCTTTTCC +CCCTCGTACACTGTGTTCTCAGGCTATACTGGTCTTCTAGCCAGTATATGCTCTTCATGC +CAGAAGCATGCCAGACATGCTCCTACCTTAGGATCTTTGCATTGCCTGTTGCCTTTACCT +GTAATGGTTTTCCCCTAGATATATGCCTGTTGGCTCACTCTTTTATTTCCTTAACATTTT +AACTCAGTTGGCACCTTCTTGGTGAGACCCAGCCCAGCCACCCTGTTTAAAATTACACCT +CTCTTCCAGGACTTCTTGTCCACCTTCCCCTGTTTTAATTTTTCTCTATAGCACTTTTCA +CCTAACAAACATATCATTTACTATATCTCGTTGGCCTCCTTCTGCTGGAATATAAGCTAA +ATGAAGACAAGTGTTTTGGTTCCTTTTATTCACTTCTATATTCCCAGCTCCTAAAATGCT +ATCTTAATAAATATTCTTTTGGATGAATGACTTGAATGAATTTGACAAGTTATTGTAATG +TATGTGGTACTGTTTTTTAAAGATTATATTCTAGTGCGAGAGACAGAAATAAAGTAAATG +AACAAATTATTATGAATCAGTTAATACAGTGAAGAAAATGAACATAGTATTGGATTAGAG +ATTAGGGAAACTCTATATAGGATTATGGGGTGATCAGGGAAGGTATCTGGGATGAGAGCT +AAAGCTGAGACTTAAATAACGATAGAGCTAAAAATTAGTGGCCAGGGATTAAGAAAAGTG +GTATAAGCAGAAAATGGCATTTGTAATATCTGAGGTTCAAAAGACATTCCAGTATAGGAA +GATAAATGCTTTTGAAGAATGAGTTCTTACTAATATTTATTGGGAGCAGGAATAATGCTT +CTGGAGTTTGATTTCATTGTTTTGAGGAGCAACAGCTCATTTGTAGTAACAGGACACACT +GTGAAAAGTGCTAGATACCTGGATTACATGCCCTTTCTCTGTCTCTCTGTGTTCCTCTAG +TAACTTGAGTTTATCTCATTGTACTTACATATAGGGGTATAGTTTGGTGTCTGTCGTGCT +ACGTTATTCTGTGAAGGGAGATTCTGTCCCGTTTGCATTTTTGCTATTCCCACTCTTCAC +TCATATAGTACCTTTGTATGGGACTTAGAAAAAGGCCTTCTCATTTATTCCTTCACCCTT +GGCTAGTGCTGATAAACCCCTGCATGTCCTACAATGTCTGCTAGTTAGTAGGTGCTCAAT +AAGTGTTTAATGATTCATGGCTGTTATAGCTGCTGAGTCAGTTAATGCACATATACTTAA +AGAAGTAGGTGTACCTTATGATAATCATTTCTGTATTTCTGTTGATTAACCTAGAGTACT +ATAGTTATGGAAGTATTTGTACCTAGTTTCTGATTTGATTTTTCTTAGTTTCAACCTCCA +AATTTGTATAACCCCAAGTATATTAGAGAGAATTGTTTTGAAGCAGGAATGACTCATGAT +AATGTAAATCCTCTCTTTAGTAAGGGTTCATAATATGGCTGAGGTATAGCTGCACTTTAA +TTTTGAAACCTGTTTTTCCTCTGACTCTTCAAGAAATATGTTTATTTTAAAAAATATAGA +ATTAGATGAAGCAGAAAGTGAAAAGTACACCTAACCCCACCACCAGAGCTAATATCACAA +ACCCTTTCTTTCATTAAACAAATATTTATTGAGCATATGTATCACTAGGCTTACAGTGAT +GAGTGAAAACAGATACAGCTCTTCTCGTGGAATTTACATTCTTGTGGGGACAGATTTGAA +AGGTAAATGTAAAAACATAGGTGTGGTAAGTGCTACAAAGTAGGAGTATGTGATGCGGTA +AGCATATAAGAGGGGGACTTCTAGCCAGGACGGTTTGGGAAGACTTCCCCGAAGAAGGGA +TGCTTGAGCTGAAAGAGAGGTGAGGTGTGTGTGTGTTTTGTAATGTGATAGATTCATTTG +TAATTCATGATATACCGTAATTTTATAAGGTTTTCATTTATGGCTGAGGTACCACTGCAT +CTCTTTTGGTACACTAATGACGTTCTGTGTTCAGTCAGTGGTTGCAGTTTTTCAGAAGAA +TCAGGGAACCTCACGTACACAGGAATTTCTAAATATTATGATTACCTTGGTTTTCTTTCT +AGCTTTGAGGTCATTTCTCTAAGAAATGACAAAATACATCAATAAAAGGGTATTATCAAG +TCAAGTCTTCATAAACCAAAGGTATACTATGAAAGGCCAAGATAATAGCAGATAATGGGT +TCATAGCTGTTAAGTCCCTCCAGTTTCTAGTGTAAGAAGGAGCATACCTTCCTGTCTGTT +CAATTATTGGCTCTCTGTGCTTGGTGTACATTTTTTTAAACTCAATTTTAATGCCCTATT +TCTGTTGGCTATCATATGGAAATAAATATAGGATAAAACTAAGTGATAGGCTAAATGGCA +TATGAAACTCTTTATAGCCCCTGTTCTTTTTTCCATTACTCTCTAAGATCTTACAGAGAT +TATGGTTAGTGTCTTTTAAGCCTGAGTTCCTAGCATGGAGTATTCCTGACATACACTAGT +GGGCACCCGGTAAATTTTGAATAAATCAAATGTCTCCTCTGTCTAATATCACAATTCATC +TCTCCAATTCATATGATCCTCAATATCTACATATTTATTCCTTTTCTCCTTGAGCTTTAA +TTTTATATCTTCCTGGATGCATGCCAGTATTTGTTTCCTTATGTCCCTCCACTGTCACCT +TCTTGCCTTGTTTTGGCCATAACTAGAGTTACCCTTTGGTAAGTGATGTTTTCATTATTC +AGGGTTTAAACCTTAACTTTTCTAGTTAGGCTTCTGTTTATTTGTGACATCCCTCGTATC +TCTTTTTTTTTTTTTTATTTAATCACGGTGTGTGTGTGTTCCTCTCAGTTAGGTTACTAC +CATGGTTTTCATCTACGCTTTGTCCCCCTAGTTAGTCTCTTACTTGGTCCTTTGTTGTTG +GAATTTTTGTCTTCTTGAAATACCTCTTCGAACATGTCTTTCGGCTTAGATAGAACTCTA +CACGGCACATAGAACTACTTCTAGCAGTCTGACTCCTTAGCCTTGTATTCACAGTCTTTC +CCTGTTTGACCTTCATTCTGTGGTTGTGCCTTTCCCTTTTGCTTCACAGTCAGACTAGCT +GATTGTCACCTCCTAGCCTCCCTTCCTCATTTGGCTGAGTGATTTGGTTTTCCTCGTCCT +TGTACTTTCTTGCCAAGTGGACTGTGAATGATAGATTGTTATATTTCTATCTCGTATTCA +GTATTTTGGTAGTCACTCTCAAAATTTGTGCTTATATGACAAGCAGTTATTCTTGCCTCA +TCCTTAAGCTCCTATTCACTTAGGTGCAGTGTGTTTGAGTTTGCAGGGGAGGGGTAGAAT +CTGTCCAAACCAGCTGTTTTTTTTGCACAGTTGCTAAACCCCCTCAACCAACTTCTTGTC +TGTTACTGGCCATTTGCAACACAGTTAATTCCTTCTTAATCAGTCATATTCACCAGTATA +TAATCTTTTCACTTTTTTCTTCTTCCACTTTCCAGTTATACTGTTCTTTCTGTTCCATGT +ATGTACTCTAAATACCTCATAAACCAGAGGTATACTATGAAAGGCCAAGATAATAGCAGA +TAATGGGTTCATTATCTGAGTCTGAAAGTGTTTGATCACTCAGATTTAATTCCATTCATT +CATACGGCAGTTTTGATGAAAATTGACTGTCTCACCTAACACGAATTGTCCCGTGGGTTT +CCTAATGAGATTTTAGATTTAGATTTTGGGGGATTCTCTGGTTTTCAAGCTAGAAGTAGA +AATTCCCTGAAAGGTTTCATGGACACTGTTCAGTGTAGTTTGTGTTTTTCTTTTATGATG +CTCATGGTTAGCCTGTTCTGAATTACTGTAACAAGACTTGGCTTTTAAAGAAAAGGCTGT +TTGACACTTAGCCTTCTGAAAGTTTGGTTTAATACGGCCCTAGTAAGAGCAAAAAAGAGA +AGGCAGAATTTGTCTTCTATCCCTGATTATGTTATTGAAATAAGATTAACATTTATAAAC +AACTGTTTTACAATAGGTTTCTATGGAGGTTTATTGCAAAAGAAAATAGCTTGACGATTT +AAGTTCCTTGAAGCCTATTGACTTTTTGGTTTTCTTAGGAACTAAATATATTACCTCTTA +ATATGTTTAGATATATATAAATATATCTTATTATATTGGTATATATTAATATATATTATT +CCCACTGGTGTACTTTAGGATAGGTATGTTAGGTGGCTCAGGATGAGGATTACAGAGGTG +CAAATAGAATCTGCTCAGAAGCCAGATTGTCTAGGGCATTATTTCACCTATGTGGACTGT +CAAATGCATCTTCCCTTGACTTACTAGAGAACTCAGAAGTAAGCAAGCCCTGGAGCACCT +GAAAGTACCAAGGATACAAATCATGTATTCCATGCTAATTGGGTTCTTTTTGAGACAGAA +GGAAAGTTCATTTTCATTAGGTAGTTTATCAAGTTTCTCCAAAAGCAACACTGAGGAATA +TAGGAGAAGCTATGAGAAATGCAGAAAGAGAAAAGAAAAAAAAAAGAGTTAAAAGAATGA +GAACAAAGGAGGGGTTAGAATGACAGATACTGGGGGCAAGTGATGGGGAGCATCAGAAAG +GACTTTGAGAGAGGACAAAAGAAAAAGCTGCCGTATTTCTTCTAAGATGTAATTTTTTTT +TTCACCTCATAACATAACATTAACTGTCTTACAGTTAATAGCATCTGAGTATTGCTTTTG +GCCAGGTGGCAGTTTTGATCTAGTTGTCATTGTACAGGCATGGCTCTGACTTGCTGTTTC +TGTTGCTGTCATTTCAGTCTCAGTGTGGACATTGTTTTAACTTCTCGTGTTGAGTAATTG +CCATTTAAAATATTTTCTTAGTTGTTGTTTTCACATCTTCATTTAGATCCTCTAGGGACA +CCAAACAGGCACCAGTATCAAAATTTGCAGGATGGTTGTCAGTGGCTTGAAAGACAGTCC +TGGAGCAGTGTCGGAACATTCTTCATACTTACATTCTTGATGGCAGAAGGATGATACTGT +GAATAAAAATTTTAAGTTATAAGAAAGCATTATGCCATTTACTTTGCAGCTTTTTCTTCC +TTCAGGGTTCATAAAATAATGCGGACTCTTAAAGTACATGACTGTATGCTTATTGAAATA +AAGGATCCCAACCATTTATTTAAAATCCTCAGCCTGATAGCAACAATGTTCATGATTATT +ACAACAATAATAACTACAGTTGCCCTTTATTGAGTATGCACTGTGTACTAAGTGTTTCTC +ACTTAATTCTCAGAACCTTTTAGGGCCATAGTATTCACGATACAAAATAGGAAAAAATGG +AGATTTTGGGTGTAAGTGTTAGATCCAGAATTTGAACCCAAGTTTATTAGGCTTCAAATC +CGGTGCTGTAGTTCCTCATCCTGTTATATAAAGTATTACTTTGTGAAAGACATAGAAGCT +TTTATGCTTAAGATAAAATTGTCTCCCTTCATCCTTCTCCCCAAAGGGTCATATCCTGAC +TTCTTTTAGCGACCTTTATATCTTTAGGGCAACTCCATTCTCCACTGTGTATCGTAGATA +GTTATGGGCACATTTCAGTTGTTCTATTAATTTGTGACTATTTAGAGTTAGTCTGGATCT +GATTTATATTTCAACTCTTTATTATCTAGCTTAGTGCCTTGCCTTTTATAGGCACTCAGT +AAATATGTGTTGTATAAATAAGGCTATAAGTGTGAGCTTAAGTTTAGCACTGGTTATTAT +GTATATTTGTGTCTCAGTAGACTCTGAAAGCATTTAGAAAAGGAGTATAGAGGACCAAAA +TTTAGCTGTCCAGTAATCTGTAATGTGTAAAGACTGTTGCAGTTGCTAAGTACAGTCTTT +TGGGATTTTCTCTATTACTGGAATAAGTGTAGAGGTGATGTAGAAGAGTATTATGGGGTG +TTAGATACACAGCTGATTTAAATTGAAGATAGGTGTTCTCAGTGTTTCTAAATTCGTTTT +ATTTAGTGAAAGGCAAAGGGGGCATGAAAAATTGAATCAACTTTTCAGGAAAGAGACTCA +AAATGTTCAGAGGTATTGCAGGTTCACTTGTGGCTCATGCAAATCAGAACGTATTTTATT +TTTTGTATACATAATGAGAAATTTTTTCATAACCGAGTACTTATGTGAGGATACTAAAGT +AAATCTATTGCTGTAACCCAAGCTCTCTGATCATTTTATTTCAAATTTTGGACCAAGGTG +TTATTTTGAATATAGTATAGTCTGCAGAAAAGACTAGGACAAAATGCATCCATTATATGG +GTACCATAAAGAAGTTTTAATCTCAGTTTAACAATTTTACTTTTACTATAGGTGGTTTAG +TTCCTTTAGAAACCTAGCTGTTAAATATTAAGAGAATAGATGAGTAAAATATGATTGCAC +CATTAAAGGCATTTAAAAAAATCTATATATTCGGGTGAGGGAAGAGCAAATGCTTGTGGT +GTTAAATAGAAAATGCAGAATACCAAGTAATATCATGTTATATCCTGTTACGGGCAGTTG +TGGGCAAGACTATATATATGCAGAGGAAACAAATATAAGCATACCATATGTTAATGGTAT +GATTATAGGTGAGTATACTTAGGAAAAATATTTTTTAAGGAAAAATATTTTTTAAAAAGT +GGTACATTGTCTCATCATTTCTGAGATCATTGTGTTCCAGTAATAAGTGTGCTAAAAATG +TCCTAATGATAATTAGAAAAGCTTTGGAGTAAGATCACCACAAAAAAAATATATTTTTAT +GCAGTGGTAGTAAGCATAAAGCTAAACCTTTCATTCCTGCTGATTGACCTAGCACAAATG +TGAGAAGGTTGGGTTAAAGTTGATAGGTTGATGACATACGTTAAGTGGTATAAAAATAAG +TTTGAAAATGAGCAAATTAAGCTGGATTATTCTTGATCTCTTAAACTATACAATCTTATG +ATAATATTTAACAATTTGAATGTTTTGGAGAAGTCAGGAATATGAAGAACAATTACAGAC +CTGTAAGGGAAGAAAATTCCTTGGCAGGAGGGTTTCTTTCTAGGAGGCAGTCTGTACAGT +GGTTTGGAATATGGATTCTGCAGCTGGACTGCCAGGGTTCAATTCTCAGCTCTGTTTCTT +GCTTTCTGTATAATTAAGCAAGTTACATTTAATTTCCCTTTGCCTGTTTTCTCATCTGTA +AAATGAGAATAATGGAATTTGCTTTATAAGGCTGTTTTGAAATTTAATGATTTTTGGTTT +CTAAATGTAAAGTCCTTAACAGTACTTGGCATAGTGAGTGCTCAATAAATGTTAGTGGTT +TATTATTATTACCATTATCAAAGGAGTATTATGATTCCTTTGCTTAAGCAATTGATTTTT +TTTTTAGAAAGGAAGCTGTTGAAGTTATTGAAGTACCTGTTGCTATATTCTAAGAAATTA +AAATGTCCAGAAATCTGCCTCTGTAAGTAACCTTTTAAGATCATTCATGCCACTCTGTTT +CTTTAGTCAGTAATAATGCAGCCCATGTTCTATGCCTTCTATAGAGAATTTCATTTAAAA +TGAAACCACTGAAAAATGTAGACCACCATTTTATACTAAATGGTGAGTAAAAGGTCTGAT +TTTATCTTGAAGAATGAAACTAAAATTCTGGGAAAACATTAGCTTATAGTAACTGTAAAC +ATGCATGAATTGTTATAATGAACAAATAATGGATCAAGTGTGAATGGATAAACAATTTTT +CCCACAAAATAATTCAGTATCATTATATGACAGCCTTCAATTTGACATTTGTGGCATTAG +CTTTAAGTTGTTCTTTTTTTTGCAAAAATATTGATAAAAATATATATACATTTTTTCAAG +GACCTCTGTTAAATTCTTTGATAGTCAAGTTACTCTTACCCTCCTCCCGAACAAAGAATG +TCTTGCTTACTGATTACTGTAAAAGTGGTAGATTCCCTGAGCTCAGTATTCCTCATCCAT +GCATCAAGACTACAAAAAAGCACAAACTCATACATATAAAACATGGAGAATCTTATAATA +CTGAAGGAAAGATTACGTGTTATTCCTTCTATACAACATTCACAAAAAGGCAAAACTATA +AAATACATCACATTATCCCCATGGGTCTTGGGGACAAACAAAACCTCAAATAATGTCAAT +GCTTATGCTGCTTGCTGTGCCCAGAGTAGCAGAGTCTCTAACCCAGGAGTCTTATGTCCT +TTGGCACCATCCAGAAGACAGTAACAGACTAACTTGTAAGTGGGGTAAAATCAAATCCTA +GATCCTACATTGTTTGCCATCATTTTTATAAACTTTGGAAATCTTGGAATTTTTGCAAAA +TCTGTAGTCTCACTCATGGTTCATAAGCCATTATGGTGAGGGAGACACTTGTGAATAGGG +ACTGATTTTATAAGTGATCAGTCACAAGTATGTTTTAAAGATATTTTTAAAAATTGAAAT +AATCATCTAGTAAAGCACACAGAATTAAAGTGTGTAGCTTAATGAACTTCTGCATATGGT +ATACATCCATGTCATCATCACCCAGATCAAAATATGGAAAATTTCTAGCTCCCTAGAAGG +CTGTCTCATGACCCTTCTTAGTGCTCTTCTGGCCTTGATGGCATAGGTTAGTTTTGCCTG +TTTTTGAATGTTGTGTAGATGGAATAATGTGTAATCTTTCCCTCAGAATATATGAGAATT +CTCCATGTTTTACACATACTAGTTCTTTCTGTAGCTGTGAAGTATTCCATTTTATGAATT +TATTACCAGTATTTACCCACTCTACTGCTGATGAATATTTGGGTTCCAGTTTGGGACTAT +TATAAATAAAGTTGTTAGGAACATGTACTTGTTTTTTGGTGGACACAGCACTCATTTCTG +TTGGATATATACCTAGGAATGGAATTTCTGGGTCATAGGGATCTATGTTTAGCGTTAGTG +GATACTGTTAAACAATTTTCAAAAGTGACTGGACTAATGTATATTCCTACTATCAATATA +TGAGAGTTCCAGTTCTGTATTATCATGAACAGTTAATCTTTTTTTTTTTTTTAAGTGTAG +CCATTCTGGTAGGTACCGAGTGAGATTTTACTGTGGTAGTTTTTGTTTTCTTTTTGCATT +CATGTGATAACTAATGATATTGAGCCCATTTTCTCATCCAGTGGCTATTTTAATGTCCTC +TTTTGTGAAGGATCTGTTCAGATCTTTTGACTATTCACTAATTTTTATGATGAATTTTTC +TCCTTTTGTAATGTAAGTTGAGACGTGGATAACAAGTACTCGGGTAGCTTGCACATACCA +CTTTACCAGTTTGGGAAGTATAGAAAACATTTTTAGAAATAATTTCATCAAAAGTGCTAA +GTTTTTTAGTCATTCCATATTTAAAGAGTTGAGTGTGAGATTTGCTCCTCTCCCTGTGCT +AGTTTTACTAGTAAGAGTTCTAGGTTTTTAAAACTGACACCTATTGTTCTTTTTGAAACC +AATCTCTTGAAGTTTAGTGGCATACCCATTCACCAAAGTCACTGGCCTTTTCTTTGTTTA +CATTCTCTTTAAACTCTCCCATATGTTTAATCTTCTGCAGTACCATTGTATCTAGTTCTG +TCTTTTTAATAGTGCATTATCAGTAACTCACTATCAGGAAACTCTTTCCTAACAGTGAAT +GTTTCGTAATATTTAGGTGTTTACTTACTGTTCTTTTCACTCTGTTGCAAACTTTTTTTT +TTTAGCTCTTTGTGCAAAATCTTAAATCTGTTTCTCATCTTTACCTGGCTAAACCTGTAT +CTCCAGTCATGACCTTTTCCCAGTGGAGTTTACCACCATTTCTACTGACAAAGCTGCCTT +CTGAATGTTTTTAATTCTGTGGGTAGAATTCTCATTTTATCATTATCTTAGTCAACGTGG +GTTTAAAATTTGAAATTATCTCTTAATTTCAAGGTACAGTTAGTAGAAAAATCAGTGACC +ATTCATTAAGTATCATAGTGTGTGGTATGGCACATGCAATGGTCCAGGTGCTGAAGACTA +CTTCTTAGAAGGATTTTGTACTGTATTTGGGAAGTTATGATATTATTTATGACTTATTAA +TTAGTTTTTATTATAAATATTCAGTGACCATAGCCTCTTCAGCATTGGGTGGTAAAGGAA +GTCTTCACAAAAGGGGATAGATTGGAGCTCATCATTAAGAATGACTAAGATTTCTCTTGG +AAGACACAGATGGGCAGAGGGGCAGGGATTTGGATTGGATCAGAAGGTGTGTATAGTGGA +AGAGTAATGGGCAAGATTAGATTAGGACTAGATCTAGCCAGTCTCTTAAGTCTTGGTTCG +TCTTCTTTCTGAATGCTAATGATTAGAATTCATGTTTGAATAGTACTGTTGAGTTTGTAA +AGCTTGTGTTAGATAGACATTAGTACTTTAATATTTCTGTGACTTAGGAACCATCATCTC +TATTTTACAGAAAAGTTAATAGGCTTTGAAAAAGTGATACTAGTAAAGAACAGAATCTGG +TGGGCACAGTGGCTCAAGCCTATAATGCCATCAACTTGGGAGACTGAGTCTGGTGTGTTT +CATTTCCAGGCATATTTTTATTCTCTGATATCATAGATATCTATAAATAACAATTTTTTT +GTTTTAAGTTTGATATAGACATCCTTAGAAAGGTATATATATTTTTACAAATTGTTTTTC +TTACTCATTTATTTGATAAATGGACACTATTCTAGGTCCAGGGCATCCAGTGGTTTTGAG +GGCAGACGAGACTACCTGCATACTAACATTGCATTGGGGAAAACAAAGTAAATAAACAAA +GTTGATAATGTAATATCAGATTAGGGTAAATGCTATAAAAAATGAACAGGGTCAGGGGAT +AGAGAATGTTGTGAGAATGGGCTGTCATGCTATTTTCAATCAAGTGGTCAGGGAATTCCT +CTTTCAGGAGGTGACCTTTGAACAACTGAATTAATTTGAGTGAGTATGCTGCGTTAAGTT +ACGGGAGAAGAGAATTTAGGGGAGAGAACATCAGATGCAAAGACCTCACATAGAAATAAC +CTTAGAATACTTGAGAAATGGAAAGAAGTTAAGTGTGGTTAAATGCAATTAGGTAGGATA +ATGGTTAAGAAATGAGTAAGGAGAAGCCAAGGGCCTGATCATGTATGATATTGTATTCAG +AATTCTGGTCTTGAAGCTCCTGTCTTTTTGCCTCCCTCTTCCTTAACTGTCTCTCTGTTG +CTCATACACATACTCTCTCACACATACGTACACTACCCTATCTAGCCCCCCATTATATTC +TAGTGTTCATGAATCAGTCAGCCAGGCCTGTCTCTTATCTAGCCTAGGAAATGCTATGTT +CATGTCTGCCTATATATATATTTTTTTGTTTGTGTGCCTTTGCCTTTGACATTTCCCATC +TCATCTCAGACAACCAAACCATGGTTTTACTTCCTGACCCACATGGATTTTATCATACAT +CCTTGATGTAGATGCAACTGAGGTCAGCCCTTCTTACAGTTCATTTAGTACATAACACTT +TATACTCTGTGACCTGTTAGTGACAATTATGCTTTCATTCTCTTTGTTATATCTCTCTAT +TTTAATGTGGCCAGTTTTGTTTGCCTAGGAAAAATCATCCTACATAGGGCTGGGCAAGAC +AAGGCACAAGGCATATCCATACATAAGGAGGATATCTTTACTTCCCTGTACCCTTCCCCA +CCATGGTTCCAGCATAGAAGGCTGGATAGCTGCCAGTAGTTGATCGGCATCCAGAACTGT +ATCTGGTACTTTAGTAGGCTCTCAGTAAGTGTATTTTGAATGAATCAGTTTATTGACTGT +TGAGATTAAACCCTACTTGGCATAACTTTTTTTAAAAAGCCCCATCATGGCTATTCACAA +TACATGGGATGTAACAAAGAATCAATAATTATTTGTTGAGTGTATGTCAGTTTTACTTTA +CTCTGTGTTTACATTATCTTTATTTACTTTATGTTATTGTCTGGGCTTTAGCTGAGCACA +TACATTCTTTTCTGGAAAGATGCACCCCAGTCCAGAATAATATTGATGCTAGAATTTTTC +AAAGACAAAGCTATAGCTTTTGGCAATTGTAGGCACAAGAAAGGAAGCATCTTTTGTTAC +ACCATTTTTCCAAACGTTATTCTTGTTACTTTAGTAGGTATTTATCGTCTGTGGTTGGCT +GTGCAGCGATCTGCAGGAGATCTTACACATTCTTTTTATTCTTTATTTAGAAATGGGATC +TCACTATGTTGCTCAGACTGGACGTGATTGAACTCCTGGGCTCAAGTGAGTCTCCCGAAT +AACTGGGATTACAGGTGTGTGCCACTGAGCCTGGTTTTTACCAGCTTCTATCGGTGGAGT +GCCTGTCACTTCCACCTGTCATCATCAGGAGCTTCTTAATGGTGCAGAACAGTGGTTTAC +CTGGAGCAAGCTCATTAACCAATATAAAATATCACTTAAAATAAGCCGATAGGAATTATA +AAATTAGAAACTGACCCTTTTAAAATGAATTTATTCTCTTTAAATTTATTCAACATACTT +AGTTTTACAAATAGATACTTGCCATTTTACTGGCAGTTATAATGATTTATTTGAGGGTTT +GGTACATCTTATACAACCGTGAATACAATTTGCATCTAATAATGTGACTTCAGTAGTATC +ATGATTTTTGTCCAAACCTTCTCAGTCTGGGAAACATTTAAAGAGAATAATGACCTTAGA +GAAGAGCTGGATTTCTTTTAAGACTTCTATTCAGATCAGGACACAATCACGTTCAAAATT +GACATAGCATGTAACATGGATTTCAGTGAAGAAAAGTACTTCAGAATCAAATTTTAGAAG +AGTGTTTTAGGGTTTAGTGGCCTAATCAAAGGGAGTCCAGAAGCTATTTTTGGATAATAC +ATAGGAGGTAGAGCAACCTGGTTTTGCCTCTGGTTATCATTTGACATTGCCAGTGTCTTA +CTTGTTCATATTATGGGGAAGGAATCGAGTGGTCACAGAACTTTTGGAGAAAATTTATCA +ATTTTTTGTTTACTTTGTAATGCTTTTCTGTTCTTATTTAATAAAATATGCCTTTCGATT +ATATTAATTTAAATTTGTATATATTGAATTGATTTAAACTAGGATCCTTTCCCCCTTTCT +CTTTCAGGACTTGACCCAATGAAAGAAGCATATGGCACTTGTGAAGATAAATGTTACTCC +TCCCTTTTTAATTGGAACTTCTGCTTAGGACCTGTGTATGACGTTTCACCTGTGATCTGT +TCTTTCGGTAGCCACTGACTTTGAGTTACAGGAAGGTCTCCGAAGATTTGTGTCAAATGA +CGTCAATGGCCAGCTTGTTTTCTTTTACTAGTCCAGCAGTAAAGCGATTGTTGGGCTGGA +AACAAGGTGATGAGGAGGAGAAATGGGCAGAAAAGGCAGTTGATGCTTTGGTGAAGAAAC +TAAAAAAGAAAAAGGGTGCCATGGAGGAACTGGAGAAAGCCTTGAGCAGTCCAGGACAGC +CGAGTAAATGTGTCACTATTCCCAGATCTTTAGATGGACGCCTGCAGGTTTCTCACAGAA +AAGGCTTACCCCATGTTATATATTGTCGTGTTTGGCGCTGGCCGGATTTGCAGAGTCATC +ATGAGCTAAAGCCGTTGGATATTTGTGAATTTCCTTTTGGATCTAAGCAAAAAGAAGTTT +GTATCAACCCATACCACTATAAGAGAGTGGAGAGTCCAGGTAGGTCTTATTCCTGAGAAG +AATTTGGAAAAACAAAAACAAAAAACCTCTCTTCCTGATATGCATGTAACTAGATTTAGT +AATGAAAAGGTTGTATTAGCTTTGTGTTTCCATCTTAAATATTCTAATCTTGGAAGGGCT +ATTGGATTTTGAGTTTAGCTTTTTATATGTAGGTGATACAATTCTCAGGTGGCTTACTCT +AATTCATTATTCACTGTAAGCACCCATATATCTACTCTGCCTTTTCCTGTGGATGACCTG +TCTCTGTTTTATTTAAAGCCTAAGCTCCAAGTGTGTACTATATCCCATTCCTTTTTGTCA +AATGAAGAACTTTGTTCCTACAGTTATCATCCTTCTCTCCAGCATTATATTTTCCCTTTC +TACCAGAGTATTTCTGATAGCATACAAGCATGCCATGATACTACCCATCCTAAAATAAAA +CTTAAAAAAAAATTCTGCTTTTCACTTCATTCACATAACCCAACCCCAATCACTGCACTG +TTTCCACTGGTCCTTTTAGAGGATTCTCCATTTTTATTATCTTTATGTTTCATTTTTTTC +TTGTGACTTCTCTAGTTAGTCTTTCTTTCCTACCATTTAACTTGTCGAGATCACTAGTGA +CTGCCTTTTTATAGGTCAAGGGGTCATTTTTGAGTCTTATCTTACTGTCCGCTCAACTGC +ATTTGATACAGTTGATCTCCTTCCATCCTACTCAAAACTTTTTCTGTGTTTGGCCCCTAA +GACAGTATGCTATCCTGGTTCTCCTACCTCACTGACTGTTCTTGCCCCTCTTTGCTGGCG +TATTCTCCTGTTTTCACAGGAGTCAGTCCATGGACCTTTTCTCCATTTATATTATTTCTT +TATGTGCTTTCATGCTGTCACATGTCTTAAGATTGTCTATAAGCTGATGCTCACATTTTG +AACTCAAGTCAACTTCTCCCTTGAGTTTTAGATTTGTGTATCCAGTTGCCTACTTGACAT +TTCCACTTGAATATTTATTTATTAAACATACCAAATGTAATATGTCTAAGCGCAGTTTTT +TTTCTCTGGTTTCCCCTATTGAAGTGAATGGCAACAGCATTCATGTAATTGCTAATGCCC +TAAACTGCAAGGTCATCTTTTATTCTTCTTACTTAAATCCTATATTTAAAATATGAGCAA +ATGCTGTTTGCTGCACCTTCAAAATATGTCTTAATAAATATGTCACCTCTCATCATTTGT +GACATCACTACTTTAGTACAGTACATCATCATCATCACTCACCTTAAGTAGTGTCCTAAT +TGGTCTTTCTGCGTCTCTTCTTCCCCTTAACCCATTGTGTTTTCCACACAACAGCCAGAA +TGATTTTTTAAAAACATACTAAATCATGTCAGTTCCTACTGAAAACACTTTCAAGGCTGT +CACACTTAAAGAGATTTCTGTAAGACTCTGTATGACCTATCCTCAGAGTTCTCTGTTCCT +TGGACTTGCCATACTCCTGTTTCCAGGCTTTAACTCTTGCTGTCTACTTATTCTCCCCCA +GGATCTTTCCATGGCACATTTTCTCATTCCATTCAGTCCTTGCTCAAATATCCGCATCAC +TAATTGACTCTATATTAGATATTTATTTTGTTTATTGACTGACATGAGCAGAGTCTTCCT +CTATTTCATTCATTACTCTATCCTTAGTGCTTAGAATAGTATATTGTTGTCTGGCACTTG +GTAGGTGATGCTCAGTAAATTTTTTTTATAATGAATGGTATAAGCTGAGCTGCTAGCTGA +GTGCATTAGTCATCTATTGCTGCATGACAGATTGCCACAAACTTAGTGGCTTAGCACAAT +GCATGTTTATTACCTCACAGTTTCTTTGGGTGAGGAGTCCAGTCACATTTAGCTGGGTCC +TTTGCAAGGCGCTGTAATCAAGGTGTTGGTTAGGGCCAAGGTCTTATCAGAAGCTCAATT +AGGGAAGGATCTGCTTCCAAGCCCATGTGATTGTTGACAGATTTAGTTGCTTTCACATAG +CCTTCTTTATAGGTAGTTCACATTCATGACAGCTTCTTCAAAGCCAGTAAGGAAGAGAGG +GTCTTCTGGTAAGAAGGACATTATATTCTTGTGGAATGTAATCATACATACGCTGTCACC +TTTGCCATATTCTGTTGGTTAGAAGGAAGTGATAGGTCATACTCATACTCAAGCAGGGAG +AATTACCCAATGGTTTGAATACCTGGAGGTGGGAATCACAGTGGTTACCTTAGAGTCTAT +CTGGGTTTCACGTGGAGATGTGTGGTAAAAAGACTGAAAATAACATTGGATGTGGAGACT +AGTAGAAAGGATAGCAGATAGCAGTGATTATGCTGTCTGTGAAAGTTCAACTTAAGAGCT +TTAGAGTGTCTTTAGACAGTTGGTATGATATGATTCTCAGTTTCTTACTGAGTCCAAGGA +AAGCTGATAGCTGAAGGAACTGATGAAGAAAGGAAGATAAAAGGATTTAATAGAGAAGTA +TAGGCTGAAAAACTCCCAAGCTTGCTATTTGCTAGGAGGGAGTCTAGGAATTTTATGTAT +TCCCCTATAGCCAAAGTGTGACTAGTAGTCAGCCAGCCAATAGAAATGTCTTATTTTTTG +TATACATTTTTCTCAGCTATGATTCATTCTATAGAAAAGACTGGGGCATAGCTCTGATAC +TTTTAAATAACGGAAAATTTCATGTCTTACTAGTTCAACTATTGGAAAGAGACTATAGAG +ACCTCATGTTTCGCCCTGAGCCCAAACTCTTGGGGGAAGGGGCAGATTACCCAGCTAGAT +TAGCTTGCTGACCCCCCATGATTAAGCAGCTATGACGCAGAATGGATCACTTCATATTAC +CAGTATTAATAAAGTAGTAGAAGGTGGTGGTAGTGATAGTAGTAACAGTGATAGCAATTA +ATATTTATTGAGCACTGATGGAATAGTGATTCCTTCATGGGGTTAGAAAAGGGTACTGAC +ATTTTACAACCCTTTCAGTTTACTTATGGGTTTATAGATAAGGAAACAAAGACTTAAAAG +GGAAGTAACTTAGGCATGCTCACACAGTTAGAATATAGTGGAGTAAGTTTTGCAAAAAGA +TAAAAAGATGGAGGATAGTTAGAAAGAGATAATGAACATAAGAAAAATAGAGGGCCAACC +TAGGTGGTCCTAGGTGTTTAGTTGAATACAGTGCACCCTAAGCTTTTTGGCACCAGGGTC +TAGTTTCATGGAAGACAGTCTTTCCATAGAATTGGTTGGGGGATGGTTTTGGGATTATTC +AAGCACATTATATTTATTGTGCACTTTATTTCTATTATTACATTGTAATATGTAATGAAA +TAATTATACATTTCACCATAATGTCAAATTAGTGGGAGCCCTGAGCTTGTTTACCTGCAG +CTAGGTTGTCTCATCCAGGCATGATGGGAGACAGTGACAGATCATCAGGCATTAGATTCT +CATAAGGAGCGCACAACCTAGATCCCTCATATGTGCAGTTGGCGATAGGATTTGCTTTCC +TATGAGAATCTCATGCTGCTACTGATCTGACAGGAGGCGGAGTTCAGGCGGTAGTGAGAG +CAATGGGGAGTGGCTGGAAATACAGATGAAGCTTCGCTCACTCTCTCTCACCATCACCTC +CTGCTGTATGGCCTGGTTCATAAGAGAGCATGAACTGGGGGGGTTAGGGACCCCTGATCT +AATAGACAGTATTGTCTATTGATTAAGACTGTGGGTTCTGGAGCCAGGCTTTCTGGATTT +GAATCCTGGTTTTACCAAATACTACCTCAAGCCTTAACCTTTCTGAGATTTAGTTTCCTC +ATTGTAAAATGGTAATAATACTACCTACCTAATAGGTTGTTATGAGCATTAGATGAGTTG +GTGCCTTAAAAAGTACTTGTTAAAACATTAAGTGGCCTGGAATCAGTTTCAAATTAAATA +TCAATTCTAATAGAATAATATATTCTGGAAATAGAGCATTGAGGAAGATGGCAGAGAGAA +AATTTTCCAAGAAATAATATCAAACACTTCCCCAAACTGAAAATTGAAAGGGCTCAGTGA +CCAAGTAATCAGAACAAAGGATAAAAAAAGCCCCACATGAAATTTTTGTATATCATAGAT +TAAAAAAAAGATTCTGAAAACTTTCCAGAAAAGAAAGACAGGAAACATATAAAGGACTAG +AAATCAGAATACTGGATTTCTCAATGCAGTTCTGGATTCTAGAAGAAAGTAAAGTAGTGC +TGTCAAAATTCAGAAGGAAATGTTATCTGCCTGCCGACAAGCAAAAAAAATAAATTTTTA +TACATGCAGGAAGTCAAGAAAATTCAACTTTTTACTTTCTCTTAGGACACTAATAGAGGA +TGAGGTCCAGGAAATGTGATCCAGCAGTAGAGAAGGGAAGTCCAAGGACTTCAGACTTGT +AGGAGACTTGAGCAGTAACCAATATAGGTTGGAACCAAAAGTTGGAAGATCTGGGCCTGG +CACGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGCAGATCACGAG +GTCAGGAGATCGAGACAATCCTGGCTAATACGGTGAAACCCCGTCTCTACTAAAAATACA +AAAAATTAGCCAGGCGTGGTGGTCAGCGCCTGTAGTCTCAGCTACTCGGGAGGCTGAGGC +AGGAGAATGGCGTGAACCCGGGAGGTGGAGCTTGCAGTGAGCCGAGATGGCGCCAGTGCA +CTCCAGCCTGGGCGACAGAGCGAGACTCCATCTCAAAAAAAAAAAGATGGAAGATCCAAG +GGAAAACGTAGAGTGAATAAATTATTTGATTATTTGTTGTATCCAAGAAATAGTAATGAT +AGGCGTTTAACAGATCTGTTGGAATTCTGGAAATATTAGTGGAATGTACTTAAAATTAAA +CAAATGAAGAAACAAGGCAATGGTTAACTTTAGTAAAAACATTGTTCAAGAAAAAGTAGA +CTCATAGTACACTTGATTCAGCAATGAATTACATGTATGTATATATGAATACTGGATATT +GATTTAAGCAAAATGTTATATTTAACTCTATTTTGGGGATGGGAGTGGGATAGAATAATA +AAAGAATGCTGCCTCATTTGCCCTAAGAGCAAGTCTACAAATAATATCTTGACTAATAAT +AGCAATATAAGCATATTATTTAGCAGTACACAAAGTAAATGTTATAAGAGATGGCTAAGA +GTTTAAATTTGTTTTCTATAGAAACAGTATATGGGAGGGGGCTAGGAATTGCAGTTTTTG +TTATAATCTCTAATAGCATGTCTTTTTTTAAACTGTCCACATATTAACATTATTTTGGAT +GATATAAAATAATTTTTTAAAAATCGTGCATAGATAATGTACAAGTGAAAGAGAAGCCAG +TGATTTTAGCATACCTCTAAAGAAAAAAAAAAGCAAATTCTTACTGAACTGAATTCCTGA +GTAGTTATTTCACTAAGTCTCTCAGATTGCTAGCCTGCTAAATGTAGAAATTCTTGCTGC +CTAATGCCCTTCTCTCCAATGGCAGCTGCCTCTTGTTCTGCGAGGGGAATAGCAGTTGTT +AACACACAGTAGAACAAAACGATTGTAGTCAGATGTTAACCACATATTTAGTATACTAAT +GCAGTAGAATGAAATGAAACAATAGACAAAAATAGCACAAATACTGACTTAACAGAAACA +CTGGATTGTTGTGTACATCCCTACTTCAGGGAGGTGAAGTGTGACTTAGGTAGCTTAAAA +ACAAACTCATTTTGTTGATGCTGAATGATATCAGAATTAAGTTGAGATTTTTCTAAGTGA +AACTACATTGACAGATACAGGACAATTGTTAATGAGATGAGTTGTAAATGTTTGAAGAAT +CAGGTTTGTTTCAGTTTCCTGCATGGAAAGGTAATCAGATATTTGAATGTGATTGGTCAC +TTGGGTCTTTAGAGAAAGCGAATATTTGAATAAAGTTTATCTCTTAAAAATGTATCTGTT +AAAAATGTTTAGACTTTGTTGTGTATATTTTCATTATGGTCATATTTAGAAGACTGATTT +TGATTGGAAGGCTTTTACCTAGAGAATATTACCATATTCAATATGGAAAACCGTACTGAA +CAACGTAAAACATGAGATCTTTCAAACTAAGAAAGATCAAAGTGTTCATAATTGGAAATG +TGGAAGTTTTTAGGGCATTCACATAACAGATTCCAACTTCACTCTGTAGTCTTAACTCCT +TGTTCAGTGCGTAGGCCAACTGATTTTCTCATCTCCTCTGCCACCCTCCCCTTCTACCTC +TTCCCAGCCCTAGTACTCCCATGTGAAATCCTCCTGTATCTTTAAGGTTCAGTCAGGTAT +GTTTTTTTCTTACAGTATTTTGTTTGATTCTCTGCTAGCTGGGAGCGCTCACCTCTGTTT +AACTCCTATTGTGTTAAATTCTCTGTTTTATGGTTGTTTTTTAATATCCTTTATCTCATA +GAACAGGAGTGGTATCTTTCTCTGGATTTTCTGTCTTCCAGGGTACCTTATGCAGGCTAA +ATGCTTACAGAGTTTTGGATTCAGTTTTTATGTAAATAGAGATTCAGGGCTCTATAAAAC +AGCCCTTTCTAAAAGTAAATTGTTTTAATAGGTTTACAGTCTTACATGAATCCTTTCTAC +CAACCCCTTAGTGTGGATGGGGCATTTGTTTAGTCATTCCTGACAAATGACTTTTGATTT +TTGTTTTTCAGTCTTACCTCCAGTATTAGTGCCTCGTCATAATGAATTCAATCCACAACA +CAGCCTTCTGGTTCAGTTTAGGAACCTGAGCCACAATGAACCACACATGCCACAAAATGC +CACGTTTCCAGATTCTTTCCACCAGCCCAACAACACTCCTTTTCCCTTATCTCCAAACAG +CCCTTATCCCCCTTCTCCTGCTAGCAGCACATATCCCAACTCCCCAGCAAGTTCTGGACC +AGGAAGTCCATTTCAGCTCCCAGGTAAGACTTTATTTTATTGATACCAAAAAAAAAAAAA +TTCCTAAGAATCACAGTTGTTCTTACTGTGGGCCCTCTGGGTGAACTGTTACATGCCAAG +GTATAATAGCTGTTTCTGACTCTTTATTCTTTAGGTAATTGTTTGATTTCCAGAAGAGTT +TAGATTTTATTTTGCCAATTACCGTATGTTTAAAAAATGGAAGTAGCCCTATTTGACTTA +AATATTTTCTTCTATTTTATGACACTCAGTACCATTTATTGTCTTTTATATAACTGATAC +TGTGATGAAAGCTATGGCATTCAATTTAATCTTCAGAATGACTATGTGAGATAGATATTC +CTGTTTTACAGATGGAAAAAGAAATTCTAAAGTAAATTTTAAACTTTTAAGTACCTTACC +TAGGGTAGGGCTAAGAACTAGAGGTTCAGACCCAGGTTTGTCTAACTCTAAAGTCTGTGA +TCTTTCACCTTTACTGTGTGGCTTTTCAAATTATTTAAGACTTTAGAAGTTAAAATGAAT +CCTGGTTATCTTTAGTTAGATAACTGATGAACTGATTTCACTGGAGAAAGATAAGTAGAT +TTTGTAAAGTTCTAAATTTTGTTAATGGCATGTCATATATGGACATGTCAGTATGTCACT +GTCAAGAAATATTTGAACACCTGCTGTTGTCAGGCAGAGTCATATATAAGTACAGTAAGT +CCTCACTTGATGTCATTGATAACGTCTTGGAAACTGACTTTAACTGAAACAGCATATTAC +AAAGCCAGTTTTATCATAGGCTAGTTGATATAAACAAGAGTTAAGTTCTTGTGGTATATT +TCTGGTCACAAAAATATCACTAAATTTATAAATAAAGACCCAAGACTCTTCTAATATTAA +ACATTGAAATAAATGTGAGCTGTGCATATCTTTAAGAAAGATCAATAAAAACAAGACTGT +TATTTACTTAATTATTCTAATTCATGGTCATGGGTAGCCAGAGCACATTCCAGCAACTCA +GGGCACAAGGTGGAAACCAATCCTGAATGGGACGTGATTAAATCACAGAGTGCACTCACA +CACACCCCGGCACTCACACTGGGACTGTTTAGACATGCATGCCAGTTCATCTGATGTGCA +CATCTTTGGGATGTGAGAGGAAACTCGGGTAACCAGAGAAAACTCAAACAAACATGGGGA +GAATGTTCAGACTCACACAGACGTGGCCCTGGCTGGGAATGGATTTTTTTTCTCATCAGC +ATCATAACAAAATGATGCTGAACAAAACACCATTGAACAAAACATTATTCAAGGACCTAC +AGTATATTCTTTGTGATTTCTCTACTGCAGCAAAATATCAATTGGTATAGTTTTTTCTTT +TGAAGAGAAATTAAGTGCCAGCTGTTTAACTTGCTATTAGGAATTTGCTCAAAAACAAAT +TTTCATAGTTTGTCTTAGATTCAGTGCTAATTGTAGTTCTGTCTCAAAATACATCCTGTA +CAAAACATTGGGATGAAAGACAAATTCGGTTCTTATTTATAATTACTGAGACAAAAAAGT +ATAGCTGTAGCTTTTGCAAAATTTTCAACTATGAGTGTTGAAACTCAAAGATTTTCTAGT +TAACATTTAGTTTCCTAAGTGAATTACCTAACCATTTAATAGGACACAACAGCCATATTT +GGATGTTGCACAAGCGTTAGACAATTGCTGTTAGTGTTGATGGCAAATTTTGAAGGGACA +TAGTTTTACTTTCCAGTTTTAAATGACAGTATACAGTATGTGCTGATCTTAATAATTTAA +AAGTGTCTCTGTAGTAGATATATACCCAAATGAGGAAAATCTGTACTTCAGATTGATATG +TAATAGCTGTAGTTTCTCTGAACACATAAAAATAAAGGCAAAATTCTTGACCTTGAATTC +TGTTTCAGTGAATTTTAGGACTGATCCTTGTATCCTGGATTACCAGGGATCTGGGCTAAA +TAAATGTGGATTTGTAGTAGGTTTTCAATTGCCATTAGGTGTGCTGTCTGTTCTCCTTTT +CCCTTGCCCTAGGATAGTATCCTACATTTTTTTGTGTGTGATGTTCAGTAATGAAGCTTG +CTGGTAATCTTAAGAATTTTCTAAAGCTTTTAGAGTAATAATTTTGAGCAGAATGAAGAT +TTTAATTATTATTTTTTTTCCTCTTAGCTGATACGCCTCCTCCTGCCTATATGCCACCTG +ATGATCAGATGGGTCAAGATAATTCCCAGCCTATGGATACAAGCAATAATATGATTCCTC +AGATTATGCCCAGTATATCCAGCAGGGGTAAGAGAAGTACTCACTTCATTTATTTTATAG +TAGTAGTTGTTTTTAACTTATTGGCTACTTTTTTAAAAACAGCTTTATTGAGGTATAATT +TATATGCTATAAAATTTTTTTGTTTTAAGTGTATGATTCAAAGATTTTGGTAAATACACC +AAGTTTTGCACCACAGTCTAGGTTTAGAATATTTCCCTAACTCTTTAAAAAGGTTTCTCT +GCGTATTTGCAGTCTATCCTCACTCCTATCCTCAGCTCCACATACCCTCTAATCTGTTTT +CTGTACCTGTAGATTTTATCTTTTCTGAACATTTTATATAATTGGAATCATGTAATAATG +TAGTCTTCTTTCACTTAGCATGTTTTTTCAAGGTTCATCCGTGTTGTAGCATGTATCAAT +AGTTTGTTCCTTTTTATTGCTTAACAGTACTCCTTTATATAAATATATCACATTTATTCA +CCAGTCAGTGGGCATTTGAATTGTTTCCGTATTTTGATTATTATAAACATTTGCAGCTGG +GCTCAGTGGCTCACGCCTGTAATCGTAGCACTTTGGGAGGCCAAGGCGGGTGGATCCCTT +GAGATCTGGAGTTCAAAACCCCAGCCTGGCCAATATGGTGAAACCCCGTCTCTACTAAAA +ATACAATAAAAATAAAAAATTACCTGGGTGTGGTGGCAGATGCCTGTAATCCCAGCTACT +CTGGAGGCTGAGACAGGAGAATCACTTGAACCCAGGAGGCTGAGGTTGCAGTGAGCTGAG +AGTGGAGTGCCACTGCACTCCAGTCTGAGCAACAGAGCGAGGCTCCATCTCAAAAAAACA +AACAAAAATCGCATGTAAGTCTTTTTGTGGATATTGTTTTATTTCTCTTGGATAGATATC +TAGGAGTGCAATTGCTGAATAACATGGTAAGTTTAACTACTTAAGAAAACTATAAAACTT +CTCTGAAGCGGCAGTACCATTTTACATTCTCACCAGCAAAGTATGAGGGTTCTATTTTCT +CTGCATCCTCCTAACACCTGTTATTGTCTGGCTTTTTAATTATAGCCATTCTAGTGGGTG +TAAAGTGCTTATTGTGGTTTTAATTTGCATTTCTCTAATGAGCAATGATGAGCATTTTTT +AAATGTACTTGTTGGCCATTTATATATCTTCTTTGATGTGTTTATTTTAAATCTTTTGCC +CATTGGGTTGTCTTACTGAGTTGTAAGAATTTTTTGTATATTCTGGATATGAATCCTTTA +TCAGATATATGATTTGCAAATATTTTCTCTCAGTCTGTGGATTTCTTTTCATTTTCTTAA +TGACGTCTTTTTGAGGGTAATAGCTTTAAATTTTGATGAAATCCATTTTGTCAGTTTTTT +CATTTCTAGATTATGCTTTTGGTGTTGAATTCAAGAAATTTTTGTCTATCCCAAGGTCAT +GAAAATATTATTTTATGTTTTATTTTAGAAGTTCTATAGTTTTAGCTCTTATATTAGGTC +AGTGGTTCCTTTTGAGTTAAGTTTGTATGTGGTATATGGTAAATGTCTACATTAAGTTTT +TTGCATATAGAAATCCAGTTGGCTTTGCCATTTGTTGAAAAGAGTATCATTTCTTTGTTG +AATTAACATCTTTGTCAGAAATCAATTGACTGTAAATGCCAGGGTTTATTTCAGGACTCT +GTTGGCTTACATATCTATACCTCATAGTCTTGATTGCTAAAGCTTTCCTATAAAGGTTTT +TCCCCCTATTTTTTTGTTGTTTTGTTTTATTTTTAATTTTTAAATTATTTATTTATTTTA +GAGACAGAGTCTTGCTCTGTCATGTCCAGACTGGAGTGCAGTGGCGTGATCATAGCTCAC +TGGAGCCTCAGACTCCTGGGCTGAAGTGCTCCTCCACCTTAGCATCCTGAGTAGCTGGGA +CTACAGGCATGCATCACCATGCTTGGCCAATTTTTTTGTTGTTGTTGAGATGGAGTCTTA +CAGTGTTGCCCAGGCTGGCCCTGTTTTTTTTTGTTTGTTTGTTTGTTTTTTTATGGCAAA +CTATATATAACATAAATTTTACCATCTTAACTATTTTTAAGTGTACAGTTCAGTGGCATT +AAATCCATTTATAATGTTGTGTGACCATCACCACCATCCATTTCTATAGCTCTTTTCACC +TTGTAGTATTGAAACTATACCTGTTAAATAAAAATTTCCTATTCTCCTTTTCCCCCAGCC +CTTGGCAACCACCACTCTGCTTTCTAATCTCTATGATTTTGACCACTCTAAGTACTTCAT +ATAAATGGAATCATACAATTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTGTGAC +TGGCTTATTTTTCCTCAGGGCACATCCATATTGTAGCAATGTCAGAATTTCATTTCTTTT +TAAGGTTGAGTAATATTCCGTTGTATGTATATACCAAATTTTGTTTATCTATTCATCCAT +TGATAGACACTTGGATTGCTTTCACTTTTTTGGCTATTGTGAATAATACTACTGTGGACA +TGGGCGTACACATATCTCTTCGAGATCCTGCTTTCATTTCTTTTGAGTATATACCAGAAG +TACAATTACTGGATTACATGGTAATTATATTTATACTTTTTTGAGGAACAGCCATACTGT +TTTCCACAGTGGATGTACCATTTTATATTCTCAGCAACAGTGCACACGGATTCCATATTC +TTCACATCCTCACCAGCACTTGTTTTCTATTTTTTAGATATTGACCATTTTAATGGGTAT +GAAGAGATATCTCACTGTGGGTTGTTCTGTATTTTTTTTATCTTTTTTTTTTTTTGGATA +ATTGACAAATGAAAAATTGTATATCTTTATGGTGTCATTGTGGCTTTAATGCCACTTTGG +TTTGAGACCTTAACCTCCTTAGTTTGTCCCAAGTTTAGAAATATGTACTGCTATTTTATA +CGTTTCTTAAAACAATGTGTTTTTATGTGTTTTCTATGTTTGTGATAATACTGAATGTGT +GTTATATTGAGTGCTCTGTATTCCTAAGAGCAGTTAAATTTCCAGACCCCTAATAGTTTT +GTTAATGTTTCTATAATGTCTAGAATTTATCAAGAAATCTCATTATATTAATTTGCCTAT +AATTTAAAATCTACCTTCATTTACCATAAAAATGGAACATGAATTTCTGGATTTGAATTC +CTGTTTCTCTACTTATTTGCTTTGCAATGTAGGTAGTTTTTAAATCTCTAAGCCTGAGAT +TCCCCATTTACAAAATAGGGATGATATGCTGGAATTATTAATATGTTGATTAAATTAGAC +AATACATGTAATGATTTTAGCACACAACATTAGGCCGTACACAATAAATAGTATTATTTT +TCTCCTTTTAAAAATATGGACTGTATTTACTCCACTTTATTCTCCTTTTGAAAATATGGA +CTGTATTTACTCCACTTAACCTCCTTTTCTTTTCTCCTGATTTTCCAGAGATCATAGTGC +CATTTAATAGTGTTATATGTTAGATGTCCATTGGAATGTAATTTGTCTCAACCAAACAAC +TGAGCCCCTTTAGAGGAACTTGATACTCACATTTTCTCACCTTTGTAGATACCTTTTTCA +CTAGAATTTCTTCTCATTTCAGTCAGATTATGTGTATTTTCTCCTTTCTTTTTGCCAAAA +AAGTGACAAAAAGAAAATCAAAGTTAAACGGCAGTGCCTGGAACCACCTGTTAGCAACAA +TACGTCTTCTGCCTTGAGCAGAGGCAGTGCTTTTCTGGTTCCTCTTTTCCTTTTAACCAA +AATTGCCTTTTTAGTTTCGCCTAGCATTTTTTTTTTTCTATAACCTTCTGCTCGTTCTTA +GCTCTAATCTTCCTGATGTTACTCTTATAACTTCATGCAACTCATTTGTACCTGTCTTTA +GGAATGGGCCTCTACATGTATAAACTTTGTATAAACTTTAAAATCTGAGCTCTTAAGACT +TCTTTGGGCTTACAGTGGTTTATTTTCCTCTCTTCCTTCTCATCTGCATTCTTTGCCATT +GAATACTCAGAATTGATTTATTTTCCTCTCTTTCTTCTCATCTGAATTCTTTGCCATATA +AAACTCAGAATTGAGTTTTAAAAGTTAAACTATTCTATTAAAAAAATAGTTGGCTGGGCG +CAGTGGCTCACTCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGCAGATCATCTGAG +GCTCAGGAGTTTGAGACCAGCCTGGCCAACATAGTGAAATCCCATCTCTACTAAAATACA +AAAATTAGCCGGGCTTGCTGGTGGGTGCTTGTAATCCCACCTGCTCGGGAGGCTGAGGCT +GGAGAATCACTTGAACCTGGGAGGTGGAGGTTGCAGTGAGCCGAGATCATGCTACTGTGC +TCAATCATGGATGACAGAGCGAGATTCCATCTCAAAAAAAAAAAAAAAAAAGTTAACCAA +TTATTTTAAATTGCCTACATAGACCATGTGATTACTCTTACATTTTCCTTGGTGTTATTT +TATTCCTGCCCCTTTTTTTTTGAGACGGAATCTCGCTCTGCCACCCGGGATTGAATACAG +CGGCACAATTCGCTCACAGTTCTCCTGCCTCAGCCTCCGACTAGCTGGGATTATCATACG +CATGTGCCACCACACCCGGCTAATTTTTGTATTTTTAATAGAGACGGAGTTTCACCATGT +TGGCCAGGTTGGTCTTGAACTCCTGACCTCACATGATCTGCCCACCTTGGCCTCCCAAAG +TGCTGGGATTACCGGTGTGAGCCACCGCACCCAGCCATATTCCTGCCTTTTTTGAAAGAG +AATTGAGGGTCTGTGATTTCTTTGCTTGATTTCAGCTCCAGGAAGGGTGCTGGGATGTAG +AGCTTCCATGTATCTCTTCTACCCTTTGTGTCTATTATGAGTTACTGACTTTTATATTAA +TGAGTTTGGCCAGTATTTTATATTGTGTATAAACCTTTTTCTGTAGGCAGTTCTGGCATG +TAAAATTTAAACATATACCTCTATTTACCCAAAGATAATGTTCATTTAGTTGTTTTGTTT +TTTTGTTTTTCTTTATAAATAGACTGCATTTTTTAGTTCAGTTTTTGGTTCACAGCAAAA +TTAAGTGGAAGGTACAGAAAGTTCTCACATACTCTCTTCTCCCACACAGGCACAGCCTCC +TCCATTATCAGCATCTCTCACCAGAGTGGGACATTTGTTATAGTCAGTGAGCTTCCATTG +ACACATGATTATTATCCAGTGGGGTTCATTCTTGGTTTTGTACATTCTGTGGGTTTTTAA +CACATGTATCCACCCTTATGATATGATACAGAATCATTTTTTACCTCTTAAAAATTCTCT +GTGCTCTGCCTGTTCACCTCTTCTTCCCCACAACCCCTTGCAACCACTGATCTTTTTACT +GTCTCTATAGTTTTGCCTTTTGCAAAATGTCATAGTTAGAATCATACAGTATGTAGCTTT +TTCAGACTGGCTTCTTTCACTTAGTAATATGCATTTAAGTTTCTCCATGTCTTTTTATGG +CTTGATAGCTCATTTCTTTTTAGCATCTCTATTAGGGTTCTCTAGAGGGACAGAACTAAT +AGGATATATGTAATATATATGAAAGGGAGTTTATTAAGGAGAATTGACTCATGTGATCAC +AAGGTAAAGTCCCACGATAGGCCATCTGCAAGTTGAGGAACAAGGAAGCCAGGGGTGGAT +CAGTCCAAGCCCAAAACCTCAAAAGTAGGGAACCTGACAGTGCAGCCTTCAGTCTGTGGC +CAAAGGCTCAAGAGCCCCTGGCAAACCACTAGTCTAAGTCCAAGAGTCCAGAAGCTGAAG +AATTTGAGTCTGATGTTTGAGGACAGGAAGCATCCAGCACAGGAGAAAGATGAAGGCCGG +AAGACTCAGCAAGTCTGCTCTTCCATCTTCTGCCTGCCTGCTTTATCCTAGCCACGCTGG +CAGCTGATTAGATGGTGCCTACCCAGATTGAGGGTGGGCCTGCCTCTCCCAGTCCACTGA +CTCAAATGTTAATCTCCTTTGGCGACACACCCACAGACACACCCAAGAAACAATACTTTG +CATCCTTCAATCCAATTAGTTTGACACTCAATACTAACCATCACAGCACCAAATACTATT +TCATTGTCTTGGTTGTACCACAGTTTGTTTATCTGTTCACCTGCTGAAGAACCTTTTGGT +TGCTTCTAAGTTTGAGCAATTATGAGTAAAGCTGGTATAAACATTCATGTGCAGATTTTT +TATGTGGATATAGTTTTCATCTCATTTGAATAAGAAGCATGATTGCCAAATTTTATGGTA +GGAGTATGTTTAGGTTTGTAAGAAACGGCCAAAGTGCCTTCTAAAATGGCTGTATCATTT +TGCATTCCCAACTATGAATGAGAATTCCTGATGCTCCTCATCCTTACCAACATTTGATGT +TGTCATTGTTTTGGATTTTGGCCATTCTAATAGGTGTGTAGTAGTATCTCATAGTTGTTT +TAATTTGCAATTCCTTAATGACATAACATGTTGAACATCTTTTCACATGCTTACTTGACC +AATCTGTGAGTCTGTGGTGGGCTCCCTACTCATATCTTTTGCCATACTTTAATCAGATTG +TTTTTGAGTTCTTTGTATATTTTGAATTATAGTCTTTTATCAGATAGAACTTTTTCAGAT +TTTTTTTTTCCTAATCTGTGGCTTGTCTCCTCATTCTCTAGACAATGTCTTTCTCAGAGC +AAAAGTTTTAAATTTTAATGAAGGCCAGCTTATCAATTATTTCTTCCATGAATTGTACCT +AAAAAAAGGCATCATCATACCAGAAGTCATCTAGATTTTCTCCTGTATTATTTTCTAGGA +GTTTTATAGTTTTGCATTTTACATTTAGGTCTGTAATCCATCTTGGGTCAATTTTGTGAA +GAGTGTAAGGTCTAGTCTAGATTTACTTTTTTGATGTAGCTGTCCAGTTGTTTCCTGTAT +CATTTTTTGAAAAGATTTTTTTTTCTTCCATTGTATTGTCTTTGCTCCTTTGTCAAATAC +CAGTTGACTGTATTTACTTGGGTCTATTTCTAAACTCTATTCTGCTCCTTTGATCTGTTT +GTCTGTTCTTTTATTTTATCATGATCTTGATTACTGTATCTTTATAGTAAGTCTTAAAGT +GAAGTAGTGTCAGTCCTCCGACTTCATTCTTCTCCTTTGATATTGTGTTGGCTATTTTGA +GGCTTTTACCTCCCCATATAAAGTACAGAATCATTTTGTCTATATCCAAAAAATAGCTTG +CAGGGATTTTGATTGGCATTATTACTCTATAGATTAAGCTGGGAAACACTGCTATCTTGA +CGATATTGAGTCTTATTCTTGAATGTGCAGTATTTCTCCATTTATTTAGTTCTTTGATTT +CTTTCATCAGAGTTTTGTAGTCTTCCTCATAGAGCATGTTCCTATTTTTTTATATTTGTG +CCTAAGTATTTAATTTTGGGGATACTAATGTAAATTATAATTTTTTTATTTTAAATTTCA +TTTGTTTATTGTTGCTGTATAGGAGAGCAATCAACTTTTGCTTATTAACCTTGTATCCTG +CAACCTTGCTATAATGCTTACTAGTTCCAGGAATTTTTTGGTCAGTTCTTTCTTATTTTT +ACATAGACAATCATGTAATTTGCAAACAAAGACAATTTCCTCCTTTCCTATCTGTGTACC +TTTTATTTATTTATGGCATTAGCAAGGACTTCCAGTATGATGTTGAAAAGTGGGAGAGGA +GGCATCTTTGCTTTGTTTTTGATCTTAGCAGAAAACCTTCTAGTTTCCTACCATTAAGTA +TGATGTTAGCTGTAGATGTTCCGTATCAAGCTGAGGAAGTTCCCCTCTATTCCTAATTTG +CTGAGTCTCACTTAGTTTTTTAGTTTAACTTTTTTGTTTAAAATAATTTTACAGATACTG +ATTATAGTTAAATCCTTCAGGTCTCTGAAAAAGAATTTTTTGTCTCAAATTTAAACCTGA +ATTAGTTTATGTTAGAAAAACAATTAAAAATGTGTTGTTGCTGCTATGTTCTGAATTGTG +TCGTCCCAAAATTCATGTTTTGAACCAAGGCCTGGGCACCTCCTCACTCCACCCAGAGGG +TTGGGAGGGTAGAACATCAAACCAAAGAGGTTTATTCTCCAGCCTTAAGGCCTAATGCAA +TTTGCTTTGCTAGGTTTTCAGCTTCCTTGACCCATCATCACTCCCTTATTTTTTGTTTTT +CCATTTTGGAATGGGAACGTCTATCCTGTGTCTGTCCCACCATAAGCACGTAACTTACCT +GGTTTCATAGGTTTACAGCTGGAAAGGAATTTTGCCTCAAGTCTCGTATGTCATATGTAG +ATGATATTTGGATGATACTGGGTTTACAACATTAGAGTTGATGTGGAAATGAGTTAAGAC +TTCAGGGGCTGTTGGGATAGAATATATGTGTGTATTTTACATGTAAGAATGATGTGAATT +TTGGGTTGCTGGGGTGGAATGCTAATGGACCATATTGAATCTCCCTAAAATTCATATGTT +GAAGTCCTAACTACCAGTGTGATGGTATTTGAAGATGGAAATAATTAGGCTTGAGAGTGG +GATTGTCATAATGAGATTAGTTCCCTTATAAGAAGAGGAAAAGAAACAGATCTTTCTCTA +AGAGCATGCACTGAGGAGGGGCCATATGAGCACACAGTGAGAAAGCAGCTGTCTGCAAGC +CAGGAAGCAGGTCCTCACTAGTTACCAAATCTTCTGGCACCTTGATCTTGGACTTCCCAG +CCCCCAGACCTGTGAGAAATAAATTTCTGTTGTTTAAGCCACTCAGCCTTACGGTATTTT +ATAGCCTGAGCAAGCTACGACTATTGCCGATCCTGGTATTTCTATAACTTTTTAAATTGT +CATATTCAAGCTGATTTCTAGTGCTTGTTTTCGGATATAGATTCACAGCTAGGAAGGACA +GTGAGACTTGTGAAATATCTGAAAATTTTCTTTTTCATGTAATACTTGGGTTGGGTTAAA +AGATAAACACATGGACAATCTGAGTTTCTGATATGTATTAAACTCTTTCTGTGTCTGGTT +TGTTCACAGATGTTCAGCCTGTTGCCTATGAAGAGCCTAAACATTGGTGTTCAATAGTCT +ACTATGAATTAAACAATCGTGTTGGAGAAGCTTTTCATGCATCTTCTACTAGTGTGTTAG +TAGATGGATTCACAGATCCTTCAAATAACAAAAGTAGATTCTGCTTGGGTTTGTTGTCAA +ATGTTAATCGTAATTCGACAATTGAAAACACTAGGCGACATATTGGAAAAGGTAATCTTG +TCATTTTCCTACATTTAATCGAATTCAATCATTTGTTGTACTTGCCATGAACCATGCATT +GTGAAAGGTGCTAGAAACATACAAAGAAGTTTGACACGTGGCCTCTGCCTTAAGTTGCCG +ATATTGAAGAATGTATTAATCAAATAAAGACATGATGTTCCCTCATTTTTTTGTCCTGCT +TAGTGTTTCTTCCCAGTGCTAAGGATCTGAAATCATACTACCACTTTGTTTTTTGAGTGT +TACCCTGACTGGAACATAAGCTGTACAGGAACTTGCTTTGTTCACAGCAGTATCCCCAGT +AGCTAGAAGAGTGCCTCATTGTAAATACACAACACATATTTATGGAATATTGTGTATGAA +TGCTGGTGAAGGATTAGAATTTTATAATTAAGGTATTTGTGGAGTATTTTGGGTTGAGAT +GACTTGTAAGTGTTACCATGATGTGAGAGGAGCGGAATTAGAAATGGGAAATCTAGTGTG +AATGATACTCCAGTGGCTTCACCACCACTGCTCCCATCTTTTAAATTTAGGCAATAAGGT +TTTATTAATAATTCATCCTGCAGATAGTTGCCATAACAAACCGGGCCCTTTTCATACTGC +AATAAAATGTCAAAGTCTCATGCATCAAGTGATCAGGAAGGAAACCCATCCCAGGTAAAG +TGTATTGCCTGTTTCTTGAGAAGTTTTGTTTTTACCCCTTGCTGCATTTTGCTTCTTTAA +CTTGAGGGCATCTTGGTCCAAAATAGGAATAAAAGGTAAATAAATATAATTGTGATAGGA +TTTCTTATAGAAGTGATTCAAAAAAATCCTGCGGCCAAAAATAAGTTACGAAACAAAGTT +TTCATTGTCTTGAGTTTACTGCCAACTTGCCTTAGTTTTTTCAGTGAAGTGCCTCACTTC +TAGGCATTGATTTTTTTTTTCTTCCATCACAGTAGAAGTAATTTAAGGGAAATCTATTTT +GTGAATTTTGAAATTCTAGAATCAGTTTTTTCTTTTTCCCCAGCATATAGTTCTAGGACC +TTTTCTTTCATGGGTTAGTTTTGGGGTGGTGGAGGGATATGTTGGGAAAATACTAGGTGA +CTAGCTTTAGTTATATAATTTGAATATTTAATGTTAAAACTATTTCCACATATTTATATA +TTTTTAAAATTTTTATTTTTTTTGCCCTCACATCTTGCAAAGGAACATATATATTTTTAA +ATATAAAAAAATTTTAAGTAAGATAAATCTGCCATTTCAAAGCTCTTCTTATGACCTGAA +ATTATATATGTAACTTTGGTTTTTTTTTAGTGTTGCTGTCCTCTTTGTTAGCACAAAGAG +TGCAAAAGTCTGTCAAATGACTGTTTATGATAGTTGATAGCACTGAGGATTTATTTGAAA +GGACTCATCAAAAGATGATTTGGGGTTTTTTTTTTTTAGCCCTCTCTTTCTCTCATAGAG +ATGATAAATGATTGTTGGGAAAGGAAAAAGAGAACAACCTAAAAATGGATAACTTAATCT +GCTGCCTATTTGAGGCTTCTCTTGTAGATGCAGGCAGACATTAACCTCTTGATTATCTTT +GGCAGCAGAAGGCCATCTAGTGGTAACTTCTGTCTAAAGACTGCTGGAAGTTTGCTGTGG +ATTAATGGGTACTTTTGTTGCACCATACAGTCTATTTGGTTTCATTGTAATGATTCTTTT +AGCTGACTCTTGTGATGTTTGTCTTTTTAAGGTGTTCATCTGTACTATGTTGGTGGAGAG +GTGTATGCGGAATGCCTCAGTGACAGCAGCATATTTGTACAGAGTAGGAACTGCAACTTT +CATCATGGCTTTCATCCCACCACTGTCTGTAAGATTCCCAGCAGCTGCAGCCTCAAAATT +TTTAACAATCAGGAGTTTGCTCAGCTTCTGGCTCAATCTGTCAACCATGGGTTTGAGGCA +GTATATGAGCTCACCAAAATGTGTACCATTCGGATGAGTTTTGTCAAGGTGAGTTGTGAC +CTCTAACATAATTTGAGTCACTATAAATGTGTATATTATGACTTTAGGTTATAATTTTTA +AAAATTGTTAAATGAAAGTTGATAATTGCTTTTGGCCTGATTTAACAGGTTTTTAAATAA +AATTATTGAATTTGTAATTTTAACTACATAATAGATCTAAGATTTCATTTTGTAATCTAG +ACATTATAAAATGCATGATTGATATTGATTTTGATATTGAATAGGGGCTGAGATTATAAG +GAATTTTAGTTAAAAGACTAAATTTCTAGAAAGCATTTGTATTAGTCCATTTTCATGCTG +CTAATAGACATACTCAAGACTGGGTAATTTATGAAGAAAAAGAGGTTTAATGAACTCACA +GTTCCACGTGGCTGGGGAAGCCTCACAATCATGGCGGAAGGTGAAGGAGGAGCAAAGTCA +TATCTTACATGGCGGCAGGCAAGAGAGAATGAGAGCCAAATGAAAGGGGAAACCCCTTAT +AAAACTATCGGATCTTATGAGACTTTATTCACTACTGTGAGAACAGTATGGGGGAAACTG +CCCCCATGATTCAGTTATCTCCCACTGGGTCCTTTCCACAACATGTGGGAATTATGGGAG +CTACAATTTAAGATGAGATTTGGGTGAGGACACAGCCAAATCATATCAGCATTTAATATT +AAAATTGCTATTTGAGTCTCTTAACTTCAACAGTTTTGATTATTATTACTAGATTTCATT +AGGGTGACTTGGCAGAATTCTTTAGAATACTAAAATTATTTCATTCCTAGCTAAGTACTG +TTATTAAAAGTAATGGCAGAAGCCACAATTACTTTTCCACCAACCTTAATATTAAGGATT +TGCAAAGTTCAAAGGAACTTTTCAAGTTTTTCATCTACTCTCTTCACCTGACTGTATTGA +CATTCCAAAGATTTGTGCTTAAAATCTGAAAAGAATTTTAGTCATGTATTTAAGCAATCT +GTACTGTATCTACATATTTAAGCAATCTGTACTGTATCTACATGGTTCTTAAGAATTTAG +CACAAGAAGAGCACCTGTCACACGCTGTGCATGGGTTTTTTTCTTTTTGGTATTCAGCCC +CAGTCCAGTGTTTTCATGATACTTTGCTGTAGATCTATTGTATACATCAGTTTACTGGTT +ACCCTGAAGGTATTTCTGCCTTCTTGTACAGTAATGTGACTTTTGCATATTTATTTTAAT +CTCCACTCCCCAATGTTCTTCACTCCCCTGACCGCCCTCCCTCCCCAACCCAGTTTTCCT +GGGCCAAGACTACCATAAGCAGTAAACCAGAGAACCTGATAAATCCAGGAAAATAAAAGT +GAAAAATTTCTATTTCAATTTTTATCTGCAGTTTTAGGCTAAAGATTTCAGCTCAGTTCA +TCCCAGTAATTTCCAACCTTAAAGGATAATCACTATGTGACTGCCACATTAAATTATACA +TGCATGTATTGATCAATATCTACAATGCCTTATCTGATATTCAAACAACTTGAAAATAAA +AAATTTTTCGTTAAAAAAAAAAACCTGGGCCGGGTGAGGTGGCTCACACCTGTAATCCCA +GCACTTTGGGAGGCCAAGGCAGGTGGATCACCTGAGATCAGGAGTTCGAGACCAGCCTAG +CCAACATGGTGAAACCCTGTCTCTACTAAAAAATACAAAAATTAGCCGGGCATGGTGGTG +GGTGCCTGTAATCCCAGCTACTAGGGAGGCTGAGACAGGAGAATTGTTTGAACCTGGGAG +GCGGAGGTTGCAGTTAGCCAAGATTGCGCCATTGCATTCCAGCCTGGGCAACAAGAGAGA +AACTCTGTCTCACAAAAAAAAAAAAAAAAAAAAAAAAAAGAAACTCTGACATGTGACATG +ATCTTACATGAGGCTATTTATGATTTTGATTTTGATTTTTTATATATGATTCCTTTATTA +GTATTTAAGTGACATCTCTTTACATTTTTTAGTGGTTTCTCCAGGAATTACCACGTTATC +TTTAACATACCCCAATCTACCTAGAGTTAATATTGTACTATTTTTAGAATGTAAAATATG +AAAACCTTGCTGTTGAAGAGTTTTAATTACCTTCTTTTATTCTTTGTGCTATTCATAAAT +TTTACATCTGCACATTATATCTTATAATACAGTTAAAATTTTTCCTTTAAATAGTCATTA +AGTCTTACAAAGAAATTAAGAGAAAATGGTATTTATAAATATTTGCAGGCAGATTCTTTG +GGGCTATGTAAATACACTGTTTCTCCTTTATATTTTACCCACAATTTTTGCATTCTTCAA +TATATCTTGTCTACAGTAATTATTACTGTGGTGTTCTAGTGGTGATTTTCTATTTTGCAT +TTATCCCATTAAGGGAGAATGTATCTCAGATCAGAAATATTTGTTTTAATTATGAGATAC +TGTACTGTGTTACCTTTCTAAGATTAAAAAAAATTATGAACTATAACTGGCTCTAAGGGT +TTCTTTTAAGGGAATTATATATTATTTTAGAATTCATGAATCTTTAAATAATGTAGCTGT +TGTCTTTTAATTTCATGGTGAATACTAAGACTGGTTTTGTGATAGTTATTCTCTTTATGT +AACTTCTACATATCTCTACTGTTAAAAGCTATCTTTTTCTTATGGTAAAATTGGTTTAGA +GTGGTTGACAGTTTAAAGAGGGATTTGTGATGATATCTGTTCATTTTCATAGGGTTGGGG +AGCAGAATATCACCGGCAGGATGTAACCAGCACCCCATGTTGGATTGAGATTATCTTCAT +GGGCCTCTTCAGTGGCTGGATAAAGTCCTTACTCAGATGGGCTCCCCTCTGAACCCCATA +TCTTCTGTTTCATAATGCAGAAGTATTCTTTTCAATTATATTGTTAGTGGACTTGTTTTA +ATTTTAGAGAAACTTTGAGTACAGATACTGTGAGCTTACATTGAAAACAGATATTACAGC +TTATTTTTTTCTACATAATTGTGACCAATACATTTGTATTTTGTGATGAATCTACATTTG +TTTGTATTCATGTTCATGTGATTAACTCTTAGAAGTGTTGTAAAAGATGCAGAGTAAGTA +TTATGCCCCAGTTCAGAAATTTGGCATTGATCTTAAACTGGAACATGCTTTTACTTTATT +GCCCTAACAATTTTTTATTAAATTTATTTGAAAATGCATCACATGATGAAAAATTATAGT +AGCTTATAAGAGGGCATATACAGTGAAGAGTAAGTTTTCCCTCCTACTCTCGATCTTCCA +GAAGCTGTACTTTTACCAGTTTCTTTGTCCCACCAACTTAAAAAAAAAAAGTACAATTCA +TTGTTTTGCAAAAGTGTATGGTAGGGGCTTAAAAGAAACTATAAAGTTTTATTTGAATGA +ACACTATGCACTGCTGTAACTGGTAGTGTTCAGTAAAAGCAAAATGATAGTTTTCTAGAT +GACATAAAATTTACATTTAATACAGATAAGTGTTCTTCAGTGTAATGTGACTTCATGCTA +TATATCTTTTGTAAGACATTTCCTTTTTTAAAAAAATTTTTGCAAATAACTGATCTCAAG +TATATGTCATTTACTCAAAATCTGTCATAAGCATTACTTTATAGCTAGTGACAGTGCATG +CACAGCCTTGTTCAACTATGTTTGCTGCTTTTGGACAATGTTGCAAGAACTCTATTTTTG +ACATGCATTAATCTTTTATTTTGCACTTTTATGGGTGACAGTTTTTAGCATAACCTTTGA +TAAAATACACTCAAGTGACTTGGACTTAGATGCTTATCCTTACGTCCTTGGTACCTTTTT +TGTATTAACAAACACTGCAATTTATAGATTACATTTGTAGGAAGTTATGCTTTTTTCTGG +TTTTTGTTTTACTTTCAACCTAGGTTATAAGACTGTTATTCTATAGCTCCAACTTAAGGT +GCCTTTTTAATTCCCTACAGTTTTATGGGTGTTATCAGTGCTGGAGAATCATGTAGTTAA +TCCCATTGCTCTTACAAGTGTCAGCTTACTTGTATCAGCCTCCCTACGCAAGGACCTATG +CACTGGAGCCGTAGGAGGCTCTTCAGTTGGGCCCCAAGGATAAGGCTACTGATTTGATAC +TAAATGAATCAGCAGTGGATGTAGGGATAGCTGATTTTAAAACACTCGGCTGGGCACAGT +GGCTCACACCTGTAATCCCAGCACTTTGGGAGGCTGAGGCAGGCAGATCATGATGTCAGG +AGTTTGAGACCAGCCTGGCCAATATGGTGAAACCCTGTCTCTACAAAAAATACAAAAATT +AGCTGGGCATGGTGGTGCGTGCCTGAAGTCCCAGCTACTCGGGAAGCTGAGGCAGAAGAA +TCACTTGAACCTGGGAGGCGGAGGTTGTGGTGAGCCGAGATCGCACCACTGCACTCCAGC +CTGGGCGACAGAGCGAGACTCTGCCTCAAAAAACAAAACAAAACAAAACACTCACCCATC +AACGAATATAGACTCTTCTCTCATTTATCGATGATCCTCTTTTTCCATTTTTTAAGTACT +TATGTGGAAGCTAGTCTCCCAAAACACAATCTTTAGAGAGAAAAGACATGAACGAACTCC +AAAATATCCATTTAATCAATCATGTTTTTGGCTTTGGATAAAGAACTTTGAACCAGTTTT +TTTCTCAGGAGCTGTCAAATGGACACTTAATTATGACATGAGAATGAAGAAATTATTTTG +GAAAAAAAAAATGACCTAATTTACCTATCAGTGAAAGCTTTATTTTCTGGTGCCTTTTGA +AAGTATATGGAGTCATATCATTCTTCTGTTTAAAATGTTAGTTTGGTTTGACTTTCCACT +TTGTCCTTTCTGCTCTTGTGAAGAAAAAAAAAAGCATTTTCGAGGAAAGAATTATGCAAT +TTCTTTTGTTTTCTGTGTCATTATTTATTGCTTTTTCAATGTGCAGCCAGTGGATGGTTT +TAGTTCTTTCAGATGAACTGCCATTTGTGTTTCAGCTCACAGTTCTTTGCTGGGTAAAAG +AAATACTTTCTGACAGTCACCTGAGCCTTAAATGTAAGTATTACATGACATGCATTCTGT +TTCTTCCAGAGTTCTGTCTGCCACACGAAAGAGAATATTTGCTTACTTGATAGAACTTTG +GCATTTTCATCATTCTTTTACTTAACCAGGCTTATGGCATGATCTCTGGAACAAATTTGT +AGGAAAAAATTACTCCAATTGAATGACTGATGTATGTAATCAACTTCATTGGGCTGCAGT +AAACTAGTGGAAATTAGAGAGTTGTTTTATTGGTGTTTTCTACTGTGAGTTAATTAAAAA +TTGTTTTTATTTGGGGTCATTATGTCACAGTCTTGAGTTAACAAGATCTTACGTGATTGG +CCTTTTCTTTGTTTTCTCTTAGGAGTTGTGTCTCATGAATGACAGTACTAAAGCTATTAA +CAACTAAGAGTTTGACAGAGAACTATAAGCCTGTTGTATCTCCTAAAAGTTGTCAACTCC +CCACCCTTGGACTTTAAATGAAAATTTTATTCAGTCCAGCTATTCTTACAGTCCCTAAGG +ATTTTCATATATCTATGTATAGGAGATAAAATTTGCTAGTAAGATTTTTAAAAACTGGCT +AGTGAAAGGAAAGTACCTCTGAAAGAAACCATTTTAGCAAATTATGGTTATATGTTTTAA +TTTAATCTACAGAATGTTTTATAGTAAAATTCTAGCACCACTAGAATAATCACATAGCAT +GTACAATATATTTATGCTGGCTGAAAAGACAGAATCTGGGAATAATAAAATTGCAACCAG +TTTGGTAATGCAAACAGCAGAATAGAATGAAATCTCAGTAATGAATTAAAGCAACAAAAA +GATATTGATTGGCAAAAAGCAAGATATAAGAGATTCATTTGCTTAACATTTCTACATAAT +ATTTATGGTCTGGTCAGTATTGGTCTGGTCAGTATTGCCTGGCTGACGTGAAATGTAAAC +TAGTAGGCGTGTTATTGATCTGCTAAAACTAACCCTCTTTTTAAGAGGAGATTTAAGGAA +GACGTCAATCAAAATGTCAAATATGTGTGTCAGAATATAAATAATTTTTCACATTGTATT +GTTGCTATATAAAAAAAATAATAGAATTGGTTGGGTTTCTGAGGTGAAATCCAGAGTAAG +AGTACTAGACAGTTCAACAAGCCACATCTAATGGCACAGATAGAGGATGTAGCTATTTTA +TACCTTTCATAACATTTGAGAGTAAGATATCCTTCAGGATGTGAAGTGATTATTAAGTAC +TCATACCTGAAATCTGTTGTCAAGATTAGAACTGGGGTTCATGTTAAAAACCTTCCATAT +TACCTGAGGGTACCTGTGGGGAACAGTTCCTTCCCCTGTGTGGTAGTATTTTGTTGGAAG +AGAATGTTTATACAAAAAATGAAATTCTTCCAACAGCAGAGAAACTCTAAAAAGTTTGAT +AGTACCTATCAAAGTGCTGTACTTCTGTGATAGAGAACATCTGATGTACCAATTTAGATC +TATTTCTTTATACTTTTTCTAATCAATTGCTTAATAGTACTTTGGATGATTATCACCTTT +GCCACTTAAAATATATAAATATCCTTTTTACTTCATGAGGAAGGAAGAATTTTTTGATAA +TTACTGAGTTCAGCCTTTTGTGATGACTTATATTTTGGACTTACATTTTAACTTTAAAGA +ATGTCAGATCCCTTCTTTGTCTTACTAGTTAAATCCTCACCTAATCTCTTGGGTATGAAT +ATAAATGTGTGTCATCGTTATATTGTTCAGCTAGATGAGCAAGTATCTTAGGGTAGTAGG +TAGCCTGGTGGTTTTAGAAGTGTTTGGTGATTTTTATGGAGAGAGTTTTCCTAAGTGGTG +GTTTATAGGTGGTATCAGATATTATTAGGGCAGCTTTTTGGGGAGTAATCTCAGGTCTCC +CAGAGCAGCAGCATTTTTCTCATTGATATAAGTAAGATTCTTAGGAGCTTTTCTTATCAC +ACAAGATGCCTGAATCGAATGTGAGAATTGAAGGCATTTCTTCTGCATAAACAAAGAATT +CTACCTGCTGGACAGAAACCTGGAAAGTTCTTTGGAATTCGCTGAATTACAGTTTAGTAT +GTCCTGATTACAGAGTGACAATATTTATCAAGCCTTTGTTATATTGGATTATCTTCTCTC +TTAAAATACAACTGTATTATAATTGAAATGACAGCCCAAAATTGGATGGTTTACCAAAAC +CAATGAAAGGGATTTCACACATCAATTTTTATTTCTGTTTTGAAGAGCACATGCTATATA +ATAATTGCTAGTAGCAACTGCAGTAAAACAGGTGATAAGTTATTTTCTCTGAAAAGATCC +AGTCCTAGAGCAGGATTCTTCGATCATTCATGGCAGAGTGAAAAAGGTTTGTATGGTTCT +TGTCCAAATAACTCAGTTCTTAAAATTCTTAAAATGATCGTAAACCATTATCCTTTAAAG +GTTTATTTGAAGATGCTGTTAAAGTACAGAATTTTGTGTACAGGTAGATTTTTCCGTCCC +TCATTAATAGTGCCTTCTTAATTAATACAGACTGGTGTTAGCTATAACAAAACTCCAGTA +AGGCCAAAGAATCCCAAGTTCTTTGTGGAAAAAAAAAAAAAATCTTTTAGGGTCAGATTT +TCCCTTCTAATATCATTGAAGATGATGTTGCATTGATTTATTCATAAAGTATTTTAACTA +TAGGAACTCTAGAAGATAATGGTTAGGCAAGTGATTTTTTTTTTAAATATGGTTGGCGTA +AGTTGTATTTTGAAATTCACTTATTTTAAAATCGAAGAGGATTGTAATCATGGAAATAGA +ATGTTTGTATCTACCTGCCCACATTTTCTTAAAAAGATATTTCATATACAGATAATGAAG +ACCAAGCTAGTGGCTGCACTGTAGGTCTGCTGCTTATTTGTATTTGTTGTGCTTCTGTTT +ATGTTGTAGAAGCTGAAATTCTAGCAACATGCTTCAATTCTGTTATTTTGATACTTATGA +AAATGTATTAGGTTTTACTATATTGTGCTTTTGAAAGCCATAACTCTTAAGAACTTTGTT +TTTGCATATTGTTTGCTAATTCTTTACTTTAATAAACCTCAAAACCTGCTTAATGTGTCT +TTTTTTGTTTTGGCTCTGGAGTTGGCCTGCCTGCGTTTGAGTCATGGGCCTCATAGCTTA +GACAAGTTGCTTAACCACTCTATGCCTCACTTTCCTGACCTGTAAAGGAAAAGTCTACTT +CATAGGAAGGATTTGAGGGAAGATTAATTGAAGTGTAATACAAATACAGTATTTAGAACA +GTACTTAGAACATAAGAACTCAAATATTAAAATTGTTACTATCTTTTACATTTCCACTAG +TTCTTTGATTCAGAATAATTACTTCTTATGTTGCTTGACCTCGGTGTATCAACCTTTGAT +GATCCACTTTGTGAATTTACAATTTTTTATTTCCTTTTGTCTTCTTTTTTGAAAAAATTT +TAAATCACAGACTGACTTTGCATCATTGTCACTGTGTTGCACACTTTTACCAACCTCTGA +ATTACATATACAAGACATGCAAACTCATTCTAATTAGAAAGGAATGGTGAGCGAGGCACA +GTGGCTCAGGCCTGTAATCCCAGCTTTTTGGGAGGCTGAGGCAGGTGGATCACCTAAGGT +CAGGAATTCAAGAGAAGCCTGGCCAACATGGTGAAACCCCGTCTCTACTAAAAATCCAAA +AATTAGCCGGGTGTGGTGGCGCGTGCCTGTAATCCCAGCTACTTGGGAGGCTGAAGACAG +GAGAATCGCTCGAACCCAGGAGGTGGAGGTTGCACTGAGCCAAGATCATGCCATTGTACT +GCAGCCTGGGCAACAAGCGATACTGCGTCTCAAAAAAAAAAAAAAAAAAAAAAAAGGAAT +GGTGAAAAATCATGTGCCCTTGCCAGAAATGTAGAAAAACCCAAACTACATATTAACCCT +AAAGGATAAAGATAAAAGCACTTGTTCTTTTTTTTTTTTTTTTTTTTTTTAATAGATAAA +AAAGACTCTATTCAAGCTTGTCCAGCCTGCACACATGGGCTGCATGTGGTCCAGGACAGC +TTTGAATACGGCCCAACACAAATTGGTAAATTTTCTTAAAGCATTATGAGATTGTTTTGC +GAGTTTTTTTTCTTTTTTTTAGCTCATCAGCTATCGTTAGTGTTAGTGTGTTTTATGTGT +GGCCCAAGATAATTATACTTCACTGTGGCCTAGGGAAGCCAAAAGATTGGACATTCCTAC +CAATTTCTGAGAATCAGTTCCTTCCTATGTCTTTTTACTTAAAAGGCATTTTGTAAGGTA +TTTTGTAGCAACATCACTGGTTGTTTTAGAAGTGTATTTTTTAAAAAAGCACACTTGTCC +TAGCGGAAGAAGGTTCAGTGAGCACTAAGAGGATGTTGGCTTCTCTTGGGTTTAAGATAA +TTAGTTTTCAGGTTGCTGTAGCCAAAACAGTTCAGGTGATGAGGGGTTGGGACAGTGGCT +AATACTATTTTGTATTACAGCAGTTTTGATGCAGCTATCGTTTTATAAACATTTTTAAGA +TTGTCAGTAGACTGCAGCAATGCTTATAAGGAAGATTTATTTAGAGCTCTGTAGTATTTA +TGATTGAAAGAAGGAAGCATTTTTAAAACACCCTTCCCATTTAACATTTTAAATATTACT +GATTTTTGTCATTGAGTTTGTAAGTCTATCATAAGCTTTGCAAAAACAAAACTTGTTCTT +TCTATCTAAATCAGTTTTTCTGTTTAAAAAAAGGGTAATGGGGCTATAGGGAAAATTCAA +AGAAGAGCTATGGGCAGCTTGCTTAACCATCTCCATGTTAACGTATGTTGGATGGGAGGT +GGGAAGAGGGATTTAGACTGGTGGTGAAGACTTATCCATATTATATCAAATGGGTGTGTG +TATAATTCCTAGTGAGAGATTTTCTGAGGCAGTTTATTGATGTTTAGAGATGGATTTTGA +AAAGATCCTTATACTTTGTCTTAATCAGTTACCCCTTCCCATCTAATAAACCTCCTTCAT +TATTTCATTTTAAATAATACTTTCATTTGAGATAAATGCTGAGAATTTTAACAGAAAAGT +TAAAACTGAAACCCCCAAACCAGTAGCAAAGGTTTATGAGTGTGCCCTTCTAACCTGTTC +TGGTAGTCACTGTACATTGATCCTTGGCTTTCTTTGACAGATACTTTGCTGATTATAGAT +GGAGCTCTAGCTCTTTTTGAAAGGGTTCTCAGAGAAATTGGTTTGGTTCTAAAGTGTTTC +TTGAGTTCTTTGTACCTAAGAAAGCCTTTCATTCTGCATAGCGTTTATCACCATCCAACA +TATATATTTCTTTACCCTGTTTATTGACTGTCTTACCTCATGGGAATGTAAGATCTGTGA +GGACAGACCTGTGTTGCCACTGCTAGAACAGTTCTTGATATGTTATAAGTAAGCATACCA +ATATTTGTTGAATGAATGAGAGTACTGAAGCAAGAAGTGAATTTTTTAAGTATTAGAATT +TACCTTTTAAATAATGTAATATTTACTTCTTAGTTGAATTGCTTCTAGCTCAATGTTTTA +TTAGCTCTCTTTATGCCTGAGAAGTGGTTTGATGTGGGGTGGGGTATTGTGGGAGCTGGC +TAAAGTATAATTGAGAAGAAGGGGAAATTCAGCTAAGAAAGCACTCATATCCTTTCTCTT +TGAACTTTTGGACTTTTGCTCCAAAGTTATCAAATTCTTGGAATTGTTGCTTGTAGAACC +TGCAAAATTAATAGTCAAGTTAGAGCTTTAACCTGTTAACATTTAATATTTTCCCAAAGA +AAGTAGGAAGGGCATAGTTTCCTTGATACGCTTGACAAGAGAAAATAACCCCAAAAAGTG +TACTTTTAATTACACAGCTTACAGAAGCTGGGGTGTTACAAATTTTGTAGTGTGATTTTA +GTGCCCTGGTTTAGACCCCATAATATCCTTCCCTAACTGTTGTACATAAGGGGCAAGCCT +TTCATTGCACTCAGGTGGGAGTGGGAGCAAGGAATACCTTTGAGAGAGAGAACGTATGAT +AAAACAAATACATGAACCATATTTGTGCTTCAGAATAAAAGATTAATTTTGCTGAAGAGT +GTGTGTGGGTGATGTAGGGGGAGAAGTTCAGGAAGAAGAAACAACAGGGTCTAGAGGGTT +TTTTAGATTTTGTCCACTTTATAGTTTTGCCAACATTAGTTCAGAAGTGTAATTAACAGT +AAACTTTCCCTAATTGCCTTTTGTTTACATAAAATTTTGTGAAATGTGGTTTTCATTAAC +TTAGAATTGTTTAGACCAAGTTAGTGAATTCAGTGAAGGTGAAGAATGCAGGCACAAACT +AGTAATGTGTAACTAGTAAGGCTGGAGAGATGATGTTCATATGAAAAGAAGGTCCTTTCC +TTTTATTGTCTGTTTAATAACCTGCTGTAAGCTTACCAATGCCCATTTGCCCTTTCATTG +CAGAACACCTGTGTCCAGCTGGATACCACGTTTCCTAGCTTTTTTTCAGCTAGGTATGGT +CATGTGACTAAGCTTGGCCAGTAGGATATTAGCAGAAGTGATAGGCACCACTTCTGCATT +ATATCTGGAAGAGGAATGCACCCCTTGCTCTTTTCCCCTTCTCAGTGGCTGGAATGCAGA +TATGAAGGCAGGATCTAGCATAGATACCTTGAAGTGGACATGGAAGCCGAGGGATGAGGA +TGACAGTTGTGCTACCCCTGAAAGAGTACTGTGCTACACCTGAAAGAGTACTGTGAGAAA +GAAACTTGCGTGGCGGATGGCTTTGTTATAGCAGTTTGGACTGTAACCTAATTAATACTT +ACTTGCCAATTGAGTGATTAACACAGGTCCAACTTTATGGTAGGCAGGGCAGTAGGGCTG +GAATCATTGTTCTTGTCCTCATGGAAAGTGAAGCTGTAACAGAGTAGTTCCGAGTTCATT +AGGTTAATCAGTTTTGGAGGGTGGAGAAGCAGGACCCACAAATGAGGGTTATTTTAAACT +ATAGACTCTACTTCTGTGTTTCTGAATATTTTTATTTTTTCTGGCCCTGAGCCGTATGAG +CTTGTTCATTCATTTGACTAATATTTGAGGGCTTGTTAGATGTCAGGCTGAGGAATAAGA +GTGGTTAAAACAAAAATTCTTTCCCTTAAGGATCTTCATTCTGGTTAATGAAGACAGCAA +ACAAGGTAAATAAAATATATGGTGTGTTTACTAGTAAGTTCCAAAGAGAAAAAAATAAAG +CAGGAAAGGAATATACCAGGGTTGGGGAACAAGGTGGAATTATAATTTTAGATATAGTAG +CCAGGGAAGGTTTCACTGAGTAAATAATCTTTGATCGAAGTCCAGGAAGATGAGGAAGTT +GTTACGTGAAGCAGTGATTTAACCAGTTCTTATTCAAGGCAATTCAGAAGGCATGTGAAT +GTTACTGCAATGATCTGTGCTTTTCTGCAGAAAATGAATAATTCAAGCAGAAATAGCTAA +AGGTACAAACTTCTATTAAATTGCTTGTTCTTTAGTCTCTGCAGGAGATATAGTAATAAC +TGAAGTGTTACACAGGTGGAGACGGGAAACGTTAGTTGCTAAGAACTTTGGATTACCACC +GCTAGGAAACCAGCCACTTGGAAGACCAATCAATAAAGGAGTGTTCAACTCAATATTTCA +CCTGATACAAGGTTAGTTTAAGGTGGAAAATCAAAGGATATGTGCTCCGATGTAAATACA +CCTTTTAAATTTACTTTAGCTCTGTTTTCCCTCTGTATTTCATTCAATAAATATTTATTG +CCTATTTTCTGTTTAAAACTATGCTAGGCATTGGGAAACAGCAGTGAACAGGACACATGT +TGTCCCTGTTCTCTGTTCATACAACTTACATGTTACTAGTGGGAAGAAGCATTGGGCTAC +TAATTATGCAGTTATTTAGTAGCTGTGATTGGGGAGGCAATATGGGGTCATGAGAGGATT +AATCTTACCTGAGGATTTAGGCAAGTCCTTTTTGAGGAAGAAACATTTAACTGGAGACCT +GAAGGATGAGAAGGCATCAGCCAGAGGAAGGAGGAGAAACAAACAGCTTAGGCAGAGGTA +GGGATTGAAAGGCCACTGGAGTGTAAGAGGAGTGAGAGAAGATGAGGCTGGTGGGACCAG +TTGATTCTGGTCCTTATTAGGCTTTTGTGTTTAATCCTGAGAGCAAAGAGAAGCCATTGG +TGTATATGCTGGGGCTGGCGGCAGATGTGTTTATTGAGTGAGGAGAGACAAAAATGGAAG +TAGGGCTTTGAGTTAGGGTTGTGATGGTGGACATAGACAGGAGTAGATGGAGTAGAGTGG +TGCCTAGGGGGTGATGAGTTACATATTGAAGGATGAGGAAGAGTTTAGGGTCAAGAATGA +CCACCATGCATTTTTTACTTTGGGCAGCCATACGCTGGTGCAGTCTATTCAGATGAAGAC +TGAAGGAGGATCTAATTTAGACAGATGAGTTTTAGGCTTGTTGAGTTCGAAGTTTCCCAT +GAGATACCCAAATGGAGGTGTTGAGTGGGCTCAGGGATAGTGTGGAGAGAGTCATCTGAA +AAGCAACTGAAGCCATGAGAGCGAATGAGATAGTTTAGGGGGAAGGTGCAAAGTGAGAAA +AGACCCAGAATAGCTGTCCTCCAACTCTGGGCATACCTGTTGGGAAGTACAGACCTCTTT +ACTGTTTCCTGATAGCACATGGCTGAAAAAGGACAGGTCACTGACAAAAAGTAGTTTGTA +CCACTGCATGCACTTCTGAAATGGCCATCCTGGTTAATAATGATAGCTCACATTCAGGGC +ATTTACTACATAGCAAACATGAGCTGAACACTTTACTGATAATGTTTCACTCCATATTGA +AAATCCTTTGAAGAAGGTATTGTCATCTCTATTCTACAGATGATGAAACGGGCTATCAGA +AATACAGAAATAACGATGAAGGCATGGAGTGGATGATCAAGCTCAGGTCATTGGCTCCAG +AACTCAGACTCTTGGTCACCACTATGCTACCTCTCCTTGACTCCTAGCATCTGCAGCTAC +CTCCCCACCGTGATCTCCAGCCTCTCCCCCAACCCCCACCAACAAAAATGCGTTAACCTC +AACCCTTCTGGCTGCTCACTGT diff --git a/test/csq/ENST00000545279/ENST00000545279.fa.fai b/test/csq/ENST00000545279/ENST00000545279.fa.fai new file mode 100644 index 0000000..a2c0ab0 --- /dev/null +++ b/test/csq/ENST00000545279/ENST00000545279.fa.fai @@ -0,0 +1 @@ +5 55942 25 60 61 diff --git a/test/csq/ENST00000545279/ENST00000545279.gff b/test/csq/ENST00000545279/ENST00000545279.gff new file mode 100644 index 0000000..b7fb620 --- /dev/null +++ b/test/csq/ENST00000545279/ENST00000545279.gff @@ -0,0 +1,22 @@ +5 ensembl_havana gene 21 55922 . + . ID=gene:ENSG00000113658;Name=SMAD5;biotype=protein_coding;description=SMAD family member 5 [Source:HGNC Symbol%3BAcc:6771];gene_id=ENSG00000113658;logic_name=ensembl_havana_gene;version=12 +5 ensembl_havana transcript 23 49909 . + . ID=transcript:ENST00000545279;Parent=gene:ENSG00000113658;Name=SMAD5-201;biotype=protein_coding;tag=basic;transcript_id=ENST00000545279;version=1 +5 ensembl exon 23 138 . + . Parent=transcript:ENST00000545279;Name=ENSE00001231815;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001231815;rank=1;version=5 +5 ensembl five_prime_UTR 23 138 . + . Parent=transcript:ENST00000545279 +5 ensembl exon 15008 15082 . + . Parent=transcript:ENST00000545279;Name=ENSE00001375348;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001375348;rank=2;version=1 +5 ensembl five_prime_UTR 15008 15082 . + . Parent=transcript:ENST00000545279 +5 ensembl five_prime_UTR 20768 20936 . + . Parent=transcript:ENST00000545279 +5 ensembl exon 20768 21339 . + . Parent=transcript:ENST00000545279;Name=ENSE00003607923;constitutive=0;ensembl_end_phase=1;ensembl_phase=-1;exon_id=ENSE00003607923;rank=3;version=1 +5 ensembl CDS 20937 21339 . + 0 ID=CDS:ENSP00000441954;Parent=transcript:ENST00000545279;protein_id=ENSP00000441954 +5 ensembl exon 28032 28283 . + . Parent=transcript:ENST00000545279;Name=ENSE00003658167;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00003658167;rank=4;version=1 +5 ensembl CDS 28032 28283 . + 2 ID=CDS:ENSP00000441954;Parent=transcript:ENST00000545279;protein_id=ENSP00000441954 +5 ensembl exon 30448 30567 . + . Parent=transcript:ENST00000545279;Name=ENSE00003585794;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00003585794;rank=5;version=1 +5 ensembl CDS 30448 30567 . + 2 ID=CDS:ENSP00000441954;Parent=transcript:ENST00000545279;protein_id=ENSP00000441954 +5 ensembl exon 39610 39831 . + . Parent=transcript:ENST00000545279;Name=ENSE00003542635;constitutive=0;ensembl_end_phase=1;ensembl_phase=1;exon_id=ENSE00003542635;rank=6;version=1 +5 ensembl CDS 39610 39831 . + 2 ID=CDS:ENSP00000441954;Parent=transcript:ENST00000545279;protein_id=ENSP00000441954 +5 ensembl exon 41552 41808 . + . Parent=transcript:ENST00000545279;Name=ENSE00003558908;constitutive=0;ensembl_end_phase=0;ensembl_phase=1;exon_id=ENSE00003558908;rank=7;version=1 +5 ensembl CDS 41552 41808 . + 2 ID=CDS:ENSP00000441954;Parent=transcript:ENST00000545279;protein_id=ENSP00000441954 +5 ensembl exon 44513 44572 . + . Parent=transcript:ENST00000545279;Name=ENSE00002232122;constitutive=0;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00002232122;rank=8;version=1 +5 ensembl CDS 44513 44572 . + 0 ID=CDS:ENSP00000441954;Parent=transcript:ENST00000545279;protein_id=ENSP00000441954 +5 ensembl CDS 44575 44655 . + 0 ID=CDS:ENSP00000441954;Parent=transcript:ENST00000545279;protein_id=ENSP00000441954 +5 ensembl exon 44575 49909 . + . Parent=transcript:ENST00000545279;Name=ENSE00002251256;constitutive=0;ensembl_end_phase=-1;ensembl_phase=0;exon_id=ENSE00002251256;rank=9;version=1 +5 ensembl three_prime_UTR 44656 49909 . + . Parent=transcript:ENST00000545279 diff --git a/test/csq/ENST00000545279/splice-region-insert.txt b/test/csq/ENST00000545279/splice-region-insert.txt new file mode 100644 index 0000000..c1a6b19 --- /dev/null +++ b/test/csq/ENST00000545279/splice-region-insert.txt @@ -0,0 +1,3 @@ +44572 T TC splice_donor&splice_region|SMAD5|ENST00000545279|protein_coding +44572 T TC splice_donor&splice_region|SMAD5|ENST00000545279|protein_coding + diff --git a/test/csq/ENST00000545279/splice-region-insert.vcf b/test/csq/ENST00000545279/splice-region-insert.vcf new file mode 100644 index 0000000..b8d0d27 --- /dev/null +++ b/test/csq/ENST00000545279/splice-region-insert.vcf @@ -0,0 +1,7 @@ +##fileformat=VCFv4.2 +##contig= +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO +5 44572 . T TC . . EXP=splice_donor&splice_region|SMAD5|ENST00000545279|protein_coding;type=ENST00000545279:135513085-T-TC, ambiguous case, curious 2bp intron with non-canonical AT..AT splicing, could also be a frameshift diff --git a/test/csq/ENST00000557788/ENST00000557788.fa b/test/csq/ENST00000557788/ENST00000557788.fa new file mode 100644 index 0000000..814a6dc --- /dev/null +++ b/test/csq/ENST00000557788/ENST00000557788.fa @@ -0,0 +1,12 @@ +>15 15:22472818-22473453 +CCGCGCCCCCTGCTGGTCCTGAGCAGCACCTGCGTCCGCGCCCTCCGCCTCCTGGCAGGG +AGGTTTGTGTCTGGGCTCACACTCACCTCCCCTCACTGTGTCTCTCGCACAGTAATACAC +GGCCCTGTCCGCGGCGGTCACAGAGCTCAGCTTCAGGGAGAACTGGTTCTTGGACTTGTC +TACTGATATGGTGACTCGACTCTTGAGGGACGGGTTGTAGTTGGGGCTCCCACTATGATA +GATTTCCCCAATCCACTCCAGCCCCTTCCCTGGGGGCTGGCGGACCCAGCTCCACCAGTT +ACTACTGCTGATGGAGCCACCAGAGACAACGCAGGTGAGGGACAGGGTCTCCGAAGGCTT +CACCAGTCCTGGGCCCGACTCCTGCAGCTGCACCTGGGACAGGACCCCTGTGAACAGAGA +GACCCACAGTGAGCCCTGGGATCAGAGGCAGCCTCCCCTATCTTCATGTCTGGATCCCTG +AGATACTCACATCTGGGAGCTGCCACCAGGAGGAGAAAGAACCACAGGTGTTTCATGTTC +TTGTGCAGGAGGTCCATGAGTCTCAGAAAGTATTTCCCATGTGAGCTGGACCCTGAATTT +AAGGAAATGTGTGGTGGTTTCCTGTGGGTGCCTAAG diff --git a/test/csq/ENST00000557788/ENST00000557788.fa.fai b/test/csq/ENST00000557788/ENST00000557788.fa.fai new file mode 100644 index 0000000..d7820d6 --- /dev/null +++ b/test/csq/ENST00000557788/ENST00000557788.fa.fai @@ -0,0 +1 @@ +15 636 25 60 61 diff --git a/test/csq/ENST00000557788/ENST00000557788.gff b/test/csq/ENST00000557788/ENST00000557788.gff new file mode 100644 index 0000000..82f9489 --- /dev/null +++ b/test/csq/ENST00000557788/ENST00000557788.gff @@ -0,0 +1,6 @@ +15 havana gene 101 536 . - . ID=gene:ENSG00000259261;Name=IGHV4OR15-8;biotype=IG_V_gene;description=immunoglobulin heavy variable 4/OR15-8 (non-functional) [Source:HGNC Symbol%3BAcc:5658];gene_id=ENSG00000259261;logic_name=havana_ig_gene;version=2 +15 havana transcript 101 536 . - . ID=transcript:ENST00000557788;Parent=gene:ENSG00000259261;Name=IGHV4OR15-8-001;biotype=IG_V_gene;havana_transcript=OTTHUMT00000415968;havana_version=2;tag=basic;transcript_id=ENST00000557788;version=2 +15 havana exon 101 407 . - . Parent=transcript:ENST00000557788;Name=ENSE00002563019;constitutive=1;ensembl_end_phase=-1;ensembl_phase=1;exon_id=ENSE00002563019;rank=2;version=2 +15 havana CDS 101 407 . - 2 ID=CDS:ENSP00000473987;Parent=transcript:ENST00000557788;protein_id=ENSP00000473987 +15 havana exon 491 536 . - . Parent=transcript:ENST00000557788;Name=ENSE00002569579;constitutive=1;ensembl_end_phase=1;ensembl_phase=0;exon_id=ENSE00002569579;rank=1;version=2 +15 havana CDS 491 536 . - 0 ID=CDS:ENSP00000473987;Parent=transcript:ENST00000557788;protein_id=ENSP00000473987 diff --git a/test/csq/ENST00000557788/ascii-art.txt b/test/csq/ENST00000557788/ascii-art.txt new file mode 100644 index 0000000..da492f8 --- /dev/null +++ b/test/csq/ENST00000557788/ascii-art.txt @@ -0,0 +1,6 @@ + +90 101 + eeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeee.... +CCCTCACTGTGTCTCTCGCACAGTAATACACGGCCCTGTCCGCGGCGGTCACAGAGCTCA.... +C--------------------------------------CCGCGGCGGTCACAGAGCTCA.... + diff --git a/test/csq/ENST00000557788/long-overlap-del.txt b/test/csq/ENST00000557788/long-overlap-del.txt new file mode 100644 index 0000000..3be9766 --- /dev/null +++ b/test/csq/ENST00000557788/long-overlap-del.txt @@ -0,0 +1,3 @@ +90 CCCTCACTGTGTCTCTCGCACAGTAATACACGGCCCTGT C coding_sequence|IGHV4OR15-8|ENST00000557788|IG_V +90 CCCTCACTGTGTCTCTCGCACAGTAATACACGGCCCTGT C coding_sequence|IGHV4OR15-8|ENST00000557788|IG_V + diff --git a/test/csq/ENST00000557788/long-overlap-del.vcf b/test/csq/ENST00000557788/long-overlap-del.vcf new file mode 100644 index 0000000..92e0a9b --- /dev/null +++ b/test/csq/ENST00000557788/long-overlap-del.vcf @@ -0,0 +1,7 @@ +##fileformat=VCFv4.2 +##contig= +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO +15 90 . CCCTCACTGTGTCTCTCGCACAGTAATACACGGCCCTGT C . . EXP=coding_sequence|IGHV4OR15-8|ENST00000557788|IG_V;type=ENST00000557788:22472907-CCCTCACTGTGTCTCTCGCACAGTAATACACGGCCCTGT-C diff --git a/test/csq/ENST00000573314/ENST00000573314.fa b/test/csq/ENST00000573314/ENST00000573314.fa new file mode 100644 index 0000000..224c62a --- /dev/null +++ b/test/csq/ENST00000573314/ENST00000573314.fa @@ -0,0 +1,544 @@ +>15 15:65871071-65903647 +AAGACAGACCAAAAGCAAACGACCTTTAGTTTCATAGTGAAACCATTTTCTAGAAAATCA +AATATTTTATTTTCATTAAAAAAAAACCTTGAATAATAGGAATCATTTTACACATTAATG +GTTGCTCTTTAAAAGTTAGAATCTCAAGAGATACCAAAAGCACTTAAGAGTTACCACCAC +ATTTTGCCCAAGTTCTAAGGAAAGTTCTGAAACTTAGTGGTGGTGTGTTTGTACTCAGCA +AGCTCCAGACAGTCTGAGTTGCTCATTCCATGAACAGAAGCTTGAAAATGCCCTTACAGT +TGAGATATAAACGAGGGAAGAGGTGAAGCTTTCAGGAAGCCAGAGAGCCCCTGCCGGTCA +GGTTTCCTGAGGAAGGCAGGGGTGCTCTATGCTCATCAGTCATTCAAGCTTCTCAGGAAA +TGTGCCCATCATGGGAACAGCAGCTATCTTCCAAGCTTAAAAATTATGAATCCCAGGAAG +TTAAAGCCCAACCAGCCAACCACCTTCACATCCTTCTCATACTAGTAGAGTCATTCAAAA +CAGCAAGTGGTGCTTCTGAGGCAGCCTCAGGAAGGTCTTTGGGTGGCTATTCTAGAGGTG +AACATACTGGAAAGGTTTTTACCTAAAGCATTTTCAGTTGAAATGAAAAAAGAAGGAAAG +CTCCAAAAGTCAGTTTCAAATTCTTTCAGTGCTGCTCCCAGAGAAGTCCGTGTGCAAAGG +TGTGATGTTCTGGTCATAAGCGGCATACTCAGAGGTGCCGGTACTGGCCAGCTTGAGCTG +CTGGGCAGCATGGGTCAGCTGGAATGCAGCATCAGGGTGGGCTGTCTCAGGCAGCAGTGT +GCATTCCCTTTCCAGCATGTCAGCCACCCCTTTCAGCAGGTCCAGGAAACCAAAGGCTAG +AGCGGCCTTTCGCAAACGGTTCAGCTCCTGAAACAAGACAGAAAATCACCAATGCTCCTG +AAATGTGTTCCTAACACATACTTTCTAAGTGCTCAGCTTAGCATAAGTTCTCCTTGACTG +AACTTTAGGGAGCAATTTTATATGAGAACAAATGTTTATTTAGGGATGCCAGTAACAAGA +ATGTGATGGTTTTACTGGGAAGTGGTTCCTCTGCAGGTGACCAGAAGCAGGCTAAGGAAG +ACAGCTGAATGAAACAACGTCATCATCACAGTTAATGAGCATTTATGCCACATGTGGTAG +TCAGCACTTTGCATCCATCATTTCGTTACTCCTAACTTTAAGGAGGAGTACTTTTCCCCT +GTTATTTAGGTATGGAAAAGACTTGCCCTCAATCTGAAAACGCTCTTAACCCTCTGATGC +CACTGTGGTGGGGCCTCAGGCTAAGACAATAAACAGGCTCAAGAGGAGGCCCTGGAGGAG +TCAGAGTGGAAAGACCAACAAAAAGAAAGGCTGGTTACTGATAGAAGCAGAGAAATATGA +AGTGCCCCAACAACCCCTTAGTGGAGTGGTCTGGGCAAGTTATATAGCCTCTCTGGGTCT +CAAAGGCCTCATTTATAAAATGAGGAGAATAACCCCTTCCTTACCCACTGCAGAGGCTGA +AGCACTTTCCCTAGGCCCTTTTGAGCTCTAATATGTAGCATTATATAAAACCAGAAAAGA +GAAATGGGCTCTCTGACCATCTTTCTACTATCATCTGTTAAAAAAGTGGAAAGTTAAGAA +GAAGGCCAAACAAGTGTGTCATCATGAGTAAATAGCTGATGACTGTAGGAAGCTCTGCAG +GGAGGATGGACTGTGTGGATTATGGGCTTCAGTTTAGGGAGGGGCCTGGCTGGCTAAGAA +GCTCTCCAGTTGAACTCTTGATTAAAGCTGTTTTATTTCACCAGCTTACTACATAATTAA +GTTTGAAGACAACAGTGACATAAAGGTAATGAGATAACACCCAGACAAAGTAGCATGTAT +CTTCTCTGGTTAAGATGCTAGCCTAAGGCTGGCTGTGTGTGCCACATTTTAGAATTAGAA +AGCTAAGACACAAATGACATACTTTATGCTGCACTTAATTTAATTCCAGCCAAACACCAG +AACAATAGGGGAGAATCAAGGAGCAAACCTAAATGTTCCCCACTCTACCCCACCCCCTGT +AACTTAACAGTCTCTTCACCAATCGTTCTGGATTAGCTGCATATGATTCTGCAGGGCTAT +CTCCTCTGCAATTCATAAATGTGTAATGTTAGATATCATTCCTAGAAGCAGAGTCTCTGG +TGCAATAAAAATGTTCTGGGGTGGCCAGGTGGGGTGGCTCACGCTTGTAATCCCAGCACT +TTGGGTGGATCACCTGAGGTCAGGAGTTCGGGACCAGCCTGGCCAACACAGCGAAACCCC +ATCTCTACTGAAAATACAAAAATTAGGCCGGGAACGGTGGCTCACGCCTGTAATCCCAGC +ACTTTGGGAGGCCGAGGCGAGCGGATTACCTGTGGTCAGGAGTTCAAGACCAGCCTGGCC +AACATGGTGAAACCCCGTCTCTACTAAAAATACAAAAATTAGCCGGGCATGGTGGCACAC +ACCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATTGTTTGAGCCCGCGAGGCG +GAGGTTGCAGTGAGCTGAGATCGTGCTACTGCACTCCAGCCTGGCCGACAGAGTGAGACT +CTGTCTCAAAAACAAAAAAACAAAAATTAGCTGGGCGTGGTGGCACGTGCCTGTAGTACT +AGCTACTCAGGAGGCTGAGGCAGGAGAATCACTTGAACCTGTGAGGCAGAGGTTGCAGTG +ACCCAAGATTGCACCACGACACTCCAGCCTGGGCAACAGAGTGTGACTCCATCTCAAAAA +AAAAAAAAAAAAAAAAAAAAAAAAAGAATGTTCTGGGCAATTCCCCATCCAGGAAGCCAC +ATACATTGGTTGCCTGGGGTTGGCCTGGATACCCATATAGGAGTGATGAGGAGAGTTCAG +GGCTATGACCCACAGGTCCTCTAAGCTGCTTCCATCAGTCATTCATTCACAGCAGCCCCA +ACACAGAAAAACCTTCTGCCTGTACAGAATTAGGCCATTTAAATTCTTCCAATTCTTGGA +TTTTAGGGAAGGAACAGACCTATCACTTTTACTGAGTTTATTTGAAAAAACTGAGGCACA +AGTCATACATCTCTAACCCCTGCCCATATTCACACTGCCATCTCACAGTTTTACTGTCGT +GAACCATATATTTTGGGCACATCCTCTTCTGTCTGTCTCACCTTATAGAATGTCTGTGTT +TTTTCAGGTAGTTTCCTTGCATTTCTTAAAATCTTCTGTACATCTGTCTATTAAGGGTAA +AAAAAAAAATCCAACATTAGAATTCTGTGGTAAAAAAGGGAAATAATATAAAAGAATGGA +TCTAAATGTTTAAAGAGATGAAAATGAGAACACAGCTACAATGTCAAGATGAGGATCCCT +TCTGAGTTAATGTCAGTTCAACATTAGTAAAGCACTCCCTCCTTCAAAAGGCTTGACAGT +AAAATAAATCCCCTGACAGAAACGAACTTGCCTCATAAAAATGTACCCAGTAAACCCATA +CATCTATTGCCAGGGACTTTTTTGCAAAGACGATTCAATGGGGAAAAAATAGTCTCTTCA +ACATTTGGTGCTGAGACAACTGGATATCCACAAGCAAAAGAATAAAGTTGGACCCTTACA +TCATACCATATACAAAAAACTAACTCAAAATGGATCAGAGACCTACATGTAAAAGCTAAA +ACTATAAAACTCTTAGAAAAAAACGGGCCAGGTGCAGTGGTGTGCCCCTGTAATCCTAGC +TACTCAGGAGGATTGCTTGAGGCCAGAAGTTTGAGACCAGCCTGGGCAACGTAGTGAGAT +GTGTTTCTCAAGAGAAAAAGAGAAGAAGAAAAAGAAAACACAGCGGGTAAATCTTTATGA +CTTTGGATTTGGCAATGATCTCTTAGTTAAGACAGCACAAAGCACAAACAACAAAAGCAA +GAGACAAAATTTGACTTCTTCAAAACCAAAAACTTTGTGTATCAAAGGACACTATAAAGA +GAGTGAAAAGATAACTCACAAAATGGGAGAAGATATTTGCAAATCATGTATCTGCTAAGG +ATCATAATATCCAGAATATATAAAAAACCCAACAACAAAAAGACAAACCCAATTAAAAAA +TGGACAAAGAACTTGAGTATATACTTCTCCAAATAATATACACAAATGGCCAATAAGCAC +AGGAAAAGATGCACATTATTGGTCATCAAGGAAATGCAAAAACAAAGACATACCACTTCA +CACCTACTATGATAGCTATATGATAATAATAATAAAAGGAAAACAATGAGTATTGGTAGG +AACGTGGAGAAACTAGAACACTTATACACTGCTAGCAGAAATGTAAAATGGTGTGGCTGC +TGTGAGAGAGTGTGGCAATTCCTCAGTAAGTTAAAGAGAATTGCTGTCTGACCCAGCAAT +CCCATTCCCATTAAAATATATACCCAAGAGTATTGAAAACAAATGTTCAGACCAAAACTT +ATACATGAATGTTTGTAACAGCATTATCCACAATAGCCAAAAGGTAACCCTAATGTCCGT +CAACTGAGGGATAATCAAAATGTGACATATACATATAGACATATGGAATATTAGCCATAA +AAAGGAATGAAGTACTGATACATACTACAACATGAATAAACCTTGAAAACATCATGCTAA +GTACAAGAAGTCAAACACAAAAGGCCACAAATTGTATGATTCTGTTTACATGAAATATCT +AGAATAGGTAAGTCCATAGAGACAGAAAGAAAATCAATGGTTGCCAGGGCCCGGAAGAAG +GAATGTGGAGTGACTTTCCTAATGGGCACAGGGTTTCCTTTTGGAGTGATTAAAATGTTC +TGGAACTAGAGAGTGGTGATGGTACATTGTGAATGTACTAAATGGGACTGAATTGTGTAC +TTTAAAATGGTTGAAGGTACATTTTATGTATATTTTACCAGAATAAGAAAAATAAACCCA +AGATAGTAGTGAAGATTCAAACAAAAAAAATTAAAAAAAATAATTTAAGAAAAGCTCAGC +TATAACTGGTGGTGAAAGTGGTTCTAATATCCCTCTGACAAGGAAGCACTGGGGTCAGGG +ATATCAGGAAAATAGAAGACCCTGATTTTCCAACAAAGAGGCCCCTGACACTTTAGCCTT +GGCAGGATGTGGTTCAGTCTCCATGGAAACGGGGCTCAGAGACTGTGCAGTCAACAGAAA +CTACTTTTGTTGTCCAAGTGGCCTGTCTCTTCTCATTTGGTTTAGGTTGAACTTACTGGA +AGAACAAATGTAAATAAAGGTGCTCAAAGGAGAAAAAAGTTTCAATAAGTGATTTTTAAA +AACAGGTATAAATGACTTTTTGCTGATGAAAGGAGAAATGTTCCTGAATACCATGCCTGA +AAGCATCATTCCTTGATAATCATATTATCATATGTTCCTGAATACCATGCCTGAAAGCAT +CATTCCTTGATAATCATATTATCATAACTTCCTATGGAAGTGTTTTTGTGAAATGTAATG +CTATGGCTTGAGTTCTACTGAAGGGATGGAAGAAATATAGTTATGAAGACTTTTACATCT +TTTCCAAAACTGTTGTTAAAGCCAATACCCATTATGTTAGTCAATGCCTCACCATATAAA +AAATTTCACACTAAAATTCAATGCCAGGAAAATATGTCTCTCTAGACAAACTGACAAATT +TCCTTTCTTTAGACAAGAACAACTGACCTTGGTAACAGGAAGCTCAGAGCCAAAACACTC +ACATAAAGTTATTATTTTGCCTTGGGTTCCTGGCACAATTGTCTTCCTTCTTCCTCCTTC +CTCTAGGATTCTTATTGCTCTAAATTTTGTAAAAAATGATTTTGCTATATACATGTTTTA +CTGTAGGGCATCTCAAATCCCTTTTGGAAATAATGACAAACATTAGAAGTAAATGAATTA +CTAAGTATCAAAGGAAAAGAAAATCAAATAAAATGCCTGCCTGCCTACCCAAATGTCTCC +TGTCCCCAGTGGAAAGCAACATAAATGGTAATGTTACCTGCAGGCCGCTGGGTTTGATCC +AGACAGTCACATTCTGGGCATAACTGCGTTTGTTTTTGGGCTGCAGGGGGAATGGACTCT +TATTGTCATCCTCGCCATAAGGGTTTTCTTTAGCATCTTAAAAGAAAAGACATTCTTGAA +ATGACATCTGGTAAAACACAATCAGTTACATTTCCATTTAGACTAGAAGCTCTTTGAATC +ACTCAATCTTTGATATCCTATCACTTTGTTAATTAAGAAAATCCATTAACTTCAGTCAGG +TTGGAGAACCTGTTCTCAATAGAAAGCCACTGATGTAGGAGGCCCATTTAAGTGAAAAAC +AGCTTAATGTTTTTAAAGAAACAAGCTTCACTTATCTGATTTATAAATTAAGGTCAAAGG +ATAAAACAAATACATATTTAAAAAATATATATATATATACATACACATAGACACACATAT +ATATACTGCAATTCTATATAGTCTAACCCAGTGCTCTCCAACTGAACTTTCTGTATGATG +GAAATGTTCTATATCTGTGCTGTCTAATGTGGTAGCTACTAACTACTAAGCACTTGCCCT +GTGGCTAGTGTGACTGAGAAACTGAATTTCAAATTGTACTTAATTTTAATTAAATTTAAT +GTGGCTAGTAGCTACTGGATTAGACAGCATAGGTCTAGGCATTAAAATAATTAAAAAGGA +AAACTATATATATAGCCAAATTAAGGCAAAGGGCAAGACAAGAAATACTTTTATTGGTGA +AGCATACCCCAATATGGCTTATTAGTTTATTGCTTCCAAAAATGTAAAGCCACATTGGTT +TTATAGCTACATGAACAAACAGGGTTTGTCTCTGTACCTGCTTCCTGAGTCTATGAAACT +GCCACAAACTTATAAAGCACACATACTTCTAATGGTGTATTTGATCTTTATTATTATTAC +CACCTTCTCGTGTAGACAGAGCAGGAGTCATTTTCCTACAAGTTCAGAGAACTTAAATCT +CTTGCCCAAAAGTTTGTGTTGAAAAATGTAATTAGACCAGTCTGTCTAATTGAGCCAGAC +ATTCTCTATCCCTGATTTGGTCATTAATTGAAACACCTTGATATTGGACCAACACTTCCT +TTGTCAACCCTCTTCAGCCCTGACTCCTCCATAAAATACTGGCCCAACTCTCCAGACGTA +TTTCCATTAATATTTGTCAATATATAAACCTTCTGAGTCAGGCTAAGGTCCTGCAAGTCC +TTTCCCACACAACAGTTCATTTCCAACTTTCCTGCTATTTCTATTACTCCTCACTGCCTA +GAATGCTCTCCCTTCTTATTCACTCATTTACTCATTCACTTATTCATTCATTATCTATAG +TAAGACCCCACTACGTAGCAAGCACTGTGCCAGGAATTGTGCCTAGAGAAGATACTTTTC +AGCCTCAAGGAACTTACAGAATAAAGAATATTTATTAAGTTCCAACTATGTGCAAGATAC +TTTACATATTCAACTTCTCTCTTTATAGCAACTCTAGAGCGAAGATGTTATTAGTCCCAT +TAAAGATGAGGAAACTAAGGCACAGAGAGGTTGGACTTATACAAGGTTTCACAGTGACTC +AGTTGGGCCTGCTTCAAAAGCCAACACTTTTTCCACCATTCAACACTGCTGTTCCTTACT +TATCCAAACTTACCTACCTATATTCCAAGTCCAGATCCTATCTTACCCCTTCCATGAAAT +TGTTTCAAGTTTTTCTGGCAGATAGTGGTTTTTGTAGACCCTTTTATCCCCTAGCACTTA +GTATCAGTACCAAACATTTCAACATCTAATCAGAGCCTATTTTGTACTGTCATTAGTTGT +CTGGAGCCTATATGTGGTAACTAACTGGCTTAGGAGACAGGAAATATTACATTTATGAAA +GAAGAAATTTTAAAAAGATAGTATAAACAAAAAATAAAAGTTATAAGATAAATTTGAAGA +TACAGAAGACAGAACAAAAATTTTAAAAATGGGAAAATGGGCAGAAAGAGATAGAAAATT +ACAAACACAAATCACAAATATATGTTCCAGAAAAGGAGAACAGAGAATACAGAAAGAGGA +AATCAAAGAAATAATTGATCTTCCCAGTACTGAAGATCATGAATTGCCAGATGGAAAGGG +TCCACTGAGTGCCTAGCAAAATCAATGAAGAGACCAACATTCTGAAATTCAGAATACCAG +GGATACAAAGAAGATCACCAAGGAATATGGAGAAAATACAGTTCAGGGTCAAAGGTCTTT +GAGTCACCATGGCACTAACTTTCCGTAGCAACACTGGACTCCAGAAGAGACAACAGAGTA +ATGCTTCAAAACTCTGAGGGAAAATGACTTCCAACTTAGAACTCAATTCCCAACCAAACT +ATCATTAAATATAAAGAATGAAATAAACATATATATATTTTCAAAATATACAAGATTTCA +AAATATTTACTTCCCATGTACCCTTTTTTTCAGGAGGAGTTATGAACAGGAGATCCATAG +GAGAGATGTAAAGGGGAGACTCAGGACAACACCTATGCAACAGGTCTGGGGAATAACCAT +ACCATTTATGAAGCAGGAGGATGGGAGATGACGCTAAGAAAAAAAAAGGAAACTGAGAAA +ATACCTGAAGAATGTATTTTACTTAGGGAGGAATTAGTTATATAGAAAACAAGCAAAGAA +AAAAAATAACTGGGACTGAGCTAGGGGACAAAAAGTTGCAAAACAAAGGAAATACAAATT +GGTATAGCTTAGTTGTAAATAACATTTACATCATGTAACAAGGACTGAATACTGATTTAA +CCAAAAAGAACATTATAACTATATTGGGAGGATAGTAGGAGGGGAAATGTGCGTCTTGTG +TAGGTGGGTGGGAGATGGTGGTGTTAATAGAGCTAAATATTCATCCTTTAAAAAGTCAAA +AAATGGCATCTAAAATGGGGGAAAAGGGCTGAGTGTGGTGGCTCACGCCTGTAATCCCAA +CAATTTGGGAGGCTAAGGTGGAGGATTGCTTTAGCCCAGGAGTTTGAGACCAGCCTTGGC +AACATAGTGAGATCTTGTCTCTATAAAAAAATCAAAAAAATTAGCCAGGCATGGTGGCAT +GCACCCGTGGTCCCAGCCACATGAGAGGTTGAGGTGGGAGGATCACCCGAGAGGTCAAGG +CTGCAGTGAGCCAAGACTGTGCCACTGCACTTCAGCCTGGGTGACAGAGTGAGACCCTGT +CTCAAAAAATAAATAAAAAATAATAAGACGGGAGGCCGGGCACAGTGGCTCGTGCCTGTA +ATTCCAGCACTTTGGGAGGTCAAGGCGGGAGGATCACTTGAGGTCAGGAGTTTTGAGACC +AGCCTGGCCAACATGGTGAAACCCCGTACCTACTAAAAATACAAAAATCAGCCAAGCGTG +GTGGTGGACACCTGCAGTTCCAGCTACTGGGGAGGCTGAGGCACGAGAATTGCTTGAATA +CAGGAGGCAGAGGTTGTAGTGAGCTGAGATCACGCCACTACAGTCCAGCCTGGGCAACAG +AGCAAGACTCCATCTCAAAATAAATAAATAAAATAATAATAATAATAATAAAATGGGGGA +ACCCCTGACAGAAATAGGGACATACCTATATTATTTAGAAATGTAAATAAGGCTGGGCAG +AGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGAGGATTACTTGAGG +TCAGGAGTTTGAGACCAGCCTGACCAACAACATGATGAAACCCTATCTCTACTAAAAATA +CAACAATTAGCCGGGCATGGTGGCTTGTGCCTGTAGTCACAGCTATTAGGGAGGCAGAGG +CAGAAGAATTGCTTGAACCTGGGAGGTGAAGGTTGCAGTGAACCAAGACTGCTCCACTGC +ACTCCAGCCTGGGCGATGGAGTGAGACTCTGTCTCAATTAAAAAAAAAAAAAGAAATATA +AATAAATACCAAAAGAAACAAATAAGTTTTAAAAAGTAGTTGTCTCTAGGAACAGAATTG +GGAGTAGGAGGGATTGGTACAAACAATAGTGCTATTTTGCATGTTTTGCTCAACAACCCT +CTGAGGTAAGTTTTATTATTAATTGTTATTTGTTATCATAATTCCAATTCCAAGACTGCT +GTGAGAGTTAAATGAGATGGTATGCTCATTATGTCCAGCACAGTGCCTGGCACAAAGTTA +AGTTCATTATAATATTAGCTATTATTATCCACACTGAAAAGCAGAACAGATCCAGGAGGA +AAAAACAACATGAACACAGGGCAGAGTGAACAGCAGTTCAACTGGAATGAAGAACAATTG +TAACAAGCCAAGTGTTGCTATGTTGGAAGCCAGATCAGAAAGGAGTCTGAATGCTACTAC +TATCTTAGATTATAGATAGGCATCTTTGGTGAAAACCATCACAATAGTCTAGTCAGAGGT +TGGCAAACTTTTTCTGTGAGGGCCAGACAGGTTGGAGTGCAGCGATGCAATCAGGGCTCA +CTGCAGCCTCTGCTTCCTGGGCTCAAGCGATCCTTCCACCTCCGCCCCCTGAGTAACTGG +GACCACAGGTGCACACCACCATGCCCAGCAAATTTTTGTATTTTTGGTAGAGATAGGGTT +TCGCTATGTTGGCCAGGCTGGTCTCAAACTCCTGGACTCAAGTGATCCACCTGCCCTGGC +CTCCCAAAGTACTGGGATTACAGGCATGAGCCACCACACCTGGCTGAATATTTATCATTT +CTTTGTGTTGTGAATATTCAAAATCCTCTCTTCTAGCTGTTTGAAAATATACACTAAATT +ATTGTGAGCAATATTCAGGCTACCATGCTACAGAGCACTGAACTTTTTCCTCCCTAACAG +CTGTAACTTTGTATCTGTTACCTCTGCCTATTCTCCTCTCCTCACTACCCTTCCCAACCT +CTAATGACCATGATTCTAGATTCTACTCTGTACTTCTATGAGCTCATTTTTTTTCAGCTT +CCATATATGGGTGAGAACATGTGGTATTTATTCCAAGTTTATTTTTGTACACAAAAACTC +AAAATTTGTGAACCACTGCCCTGAGCAATCTCCCTCATTCTCACCATTTTAACTATTTAT +GATAGGCTTACAACCTAAAATTTTATCTCCAACTCTGCCCTCTCTCCTAAACTTCAGACT +TCTACAGAATTGTCTCTAGGTACCTCCACCTGTATCTCACAGGCACGAACTCAACATAAA +CAAAATATGTTCTTCCCAAATTTACTCTTCTCTCTGTATTATCTATTTCAACTAATAGTA +CTATCTTTCACCCTGCAGCCCAGGTCAGAAACCTGGGATCAATTTTAACACTTCTCTCTC +CATAATTTTCATATCCAAACATTATTGATCCTACCTCCTAAATATCTTTTACCCCCAGCT +ATTGCCACGGTCTGGCTCTCATCTTCACATTTCCAGGATTAACACAGTAACTTTCAGCCA +CAGGTCCTTGCCTTTTCAGATCCACACTCCACAGAGATATCTTTCTAAATACAAATTTCT +TATCTCTCACTTGGATTATGGCCATACTGTACAACTGCAGGGGGCACCAGCCCCTAAAAT +ATAGTTTCCTAACTGGTATCCCCCTGTTCTCACTGTAGCCAGAAGGATCTGATCACATTA +CTCCTCTTCAGTGGTTTCCCAGTATCTGCAAGATAAATTCCTGGTTCTTCACATTTCAGA +CAAGGCCTGCTCCACTCTAGCTACTACCAATCTCCAATCTACCATCTGCCCCTCCCACAC +CCACTCTCACATTTTGTGCCACACTTCCTTTTCTTTCTGTAGGTGTTCTGTTTGCCCAGG +ATGCCCTTTCTTCCCTTCATTAGCTCAGCAAGTTCCTCCTTTTCTTCAAAACTCAACTAG +GGTATTTCTCCTCTGTGAAGATTCTCCTGAGTCCTCTAGGCAGAGCTCATCATCATCTCC +TCCAGGCTAACTCTGATTTGTGCCAGTCTGTGATCATTCCACTTTCCACTAGACTTTGAA +CAACTCCAGCTAACTCTTTATCCCTTAGGCCTGGCACAGAATAGGTTGCTTGGTAGATGT +TCCTGAAATTGAAATGGGCCCAAATGAGTCAAAGATGACTACAGTTGGAACCTGAGTAGC +TAGTGGCACAAATGACTTAATCAAAAGGAGGAGGAAAATCAGAAGGAGGAATAGTTTGAG +GAGAAAGGGGTGCGGGACAATAGGTCTGTAACAAACAGCTGAGCTTGAGACTGTGACAGA +ATATCCAGGTGTAGAGATCCAACTAGGAACTGGAAATATGATATGCAAATTCCAGGGAGA +GATCAGGTAAGACTAGAGTTATAGATTTGGGAAATGTGAAGTTATTACAGCTGATAAAAT +AACCAAGGGAGAAGAATAACCAAAGAGAAGAAGGCAAAGAACATGTTGGAAACCATGAGG +CAAGGAGAAGAAAAGACAAAACGAAGAGAGAAAGAAAAGTCCGCCAAAGAAAAAGTCAAA +TCGGTACCAGAAGCAATGTCAGGAAAGCTACAGAAAAAAAGTTTCAAGAAGGAGGAAAGA +TTACATTATCTAGGAATGACAGGAAATTACTTGAACTATAGTACACCAAGAAAAAAAATT +ATGGAGATTAGTTTTTCACTCTAAGCCGCTGAAGAATTTGCATTTACTTAAAGCAATCTA +AATGTTGATTTCTCCTGAGCTGTAAAATTTAGGAGTTCAAACATCAAACTCTCTTCAAGT +TTTCACCGTACACATCCAGCATCATCCGAGACCATGGCATACCAGTAAGGGAGATCAATC +AGTTCTCTGACTGCACAGTCAGAGACATTGAGAACAGCAGAATGAAAACAAAGTCAGGAT +AAGTAAAATCTGATCTGGATTATACCTGAAATAGGACCCAACTGTGCCATTTTCCCTAGC +CATGGGAGAGGTTCTGGGCCAGGCTCAAAGAGAGACATCATGAGGTTTGATTTCTTCTTG +CTGTCAGCTTGGGAGTAGAGCATTCCATGCCATTCAGGACTAGATGGAGAGAAGACGGAA +GATCAGAAGAACATCAAGCCTGAGACTGTCAAGTTAAATAAGTCTAGCCTGTATTTTTCT +CTTGAGAGACACAGGCTTCAGCTTTGAAATCAGGCACACTACTTTTACCAAAGCCAAACC +CTAAACCTGAAAATGCATACTGCTGTCCCCTAATATTTCCATTCTTCTGAGACATTTATT +ATTATTCAGGTAAAATTATGTGGATATGGAAATCAAAAGCAATCTTGAAAGAGAAAAAAC +AAATCACAAAGGGCAGCAAGTAGCTGGAGAGGTGATGAGGAGGGGTAAAGGCTGTGACCT +ATAGGTCCTGTCACCTGCCTCACTGAGTCACTCACAGCAGCACCAAGAGAAGCCCTTCTA +CCACAGGGCTCAAGGCCATCATCCTGTTATGTAAAAGAGACTCTGTCCCCAGTTTCTCAA +AGGGTCCCAGATGATTCTCATATTCAGACCAGTACAAGTAGCTTGGGTGCCAAGAAATAT +AGCAGACTAATATCTAGTAAGATCTGCATTCCTCTTTTTGGACCAGCTAATTTTAACTGT +AGCAGAAATGGAGCCATGCTTCCTTTAATTAATCCTAACTCTTGATCTATACCAGCCAAC +CCCAGGTAGTGGCCAGAAAATGATCAGTGACCTCCTTTTTTCTAAAAATATGTATTATAG +AAAGGGAAATAGATGGTTTTGCAGATTTTGAGACTTCAGAAAATGTAAAAGCTAACGGGG +TTTCCTCACAGGGAAGGAACACAGCAGAATGATTATGAGTAGGCTCTGGAGTCAGAATGC +ATGGGTAAGAATCATGGTTCTTTCATTACTAGCTGTGTGACCTTGGGCAAGTTCCACAAC +CTCTCTTAAGCCTGTCTCCTCATCTATAGATAGGGATAATGCTGATACCTCCCATATAGT +GTTGTTATGAGGGATTAAATGTGCTAACATATGTAAAATACCTAGAGGAGTGCCTGGCAC +ATAATAAAATGCTCAATGTTATTAGCATCTTTTTTTTTGTTTCGTTCTATCCCCTCATTT +TATAGATGAGAAGTCTGTGAATCCTGCCTAAGATCCTAAAGCAAGTTAGTAGCATTGCTA +TAACCAGAACCCAGGTATTCTAGATAGGATTAGAAAGAGGAAAATTGAGAAAGGATATAA +AATAAAGGCAACGTAATTAAAAGGCTCACTCCACACTTATTCTAGGGGATGATTAAAAGA +GTAGTTTAGAAGGTAATAGCAGCTAGGTACTGTGGCTCAATGCCCGTAATCCCAGCATTT +TGGGAGGCCAAGGTGGGAGGATCCTTGAGCCCAGGAGTTCAAGACCAGTGTGGGCAACAC +AGTGAGACCCCACTTCTATAAATTAAAAAAAAAAAAAAAAAATTAGCCAGGCATGGTGGT +GCACACCTGGGTCATGGCTACTTGGAAGGCTGAGATGGGAGGATTGCTTGAGCCTGGGAG +GCTGAAGCTGCAGTGAGCCGTGATCATGCCACTGTACCCCTGGGGGACAGAGCAAGACCT +CGTCTCAAAAAAAACAAAAAAAAAGGACTGTAGTAGCAGGTGGGAAAAGTGTGTGGCAGG +AAAAGGAAAAAGGTGACAAGGACCTTTCTATTTCCTTCAGAAAAGTCTGCAAAATACTTC +ACTTTGTAAAATGATTTTCCCTTTCATTCAACCAAATGTAAACAAAGTTTCCTACCCTAA +TTGAACAATCGCTACCATTCCTTCCACTTTTAGGCTACCATGGAGCAGGACACAAAAGTT +GGGTATTTTGCCTGCAATCTGATTGGCTGAATTTTCATCTTCATTGTCATCAGTGATGCC +AGTACCCACCTCATCACCTTCTGTGAAAAAAAGAGAAAACAGGTCAGACTGAAATTACCT +ACAAAAACCCCAAACCCCAATTTATACTCTTGGATGTTTCTAGCCTTTAAGGGATAGTGT +AGAGTTCTAAGGGAATATTATAACAAGCAGGAAAAACTCATTCCAGTTTTCCAATATCTA +CATAAAAGTCAGTTTCCACACATTATATGAATTCCATTTATATAAAACATCCAGAATAGG +CAAATCTATATATACAGAAAGGATATTAGTGGTTATTTGGGGTAGGGGAAATGGGGGGAG +GGGTCTGGGAGTTGATAGTTAAAGGGTACAGGGTTTCTTTTTGGGGTTATAAAAAAGTTC +TCAAATTGATTGTGGTGATGGTTGCACAACTCTGCAAATATACTAAAAACCACTTTAAAT +GGGTGAAGTATATGGTATGTGAATTATATCTCAGTAAAGCTTACACACAAAAATCCATTC +TCCACAGTTCCACTAGGATGTTTAGTTAGATGCTATCTGGAAGCTTCAGGCACCCATTTA +AACAGAATTAGATACAGAGATGTCAAGTGCATTCATAACCAACAGGCTTAGGGCAGCACA +TGCATGTGAGTCCCCAAAGGTAAACAATGATTATAAGCTTTTTGACTGGATTCTCCAGTT +TCTCTCACACTCTGCTGACAGATGAATCTTCCTACAATTAACTTCCCTCTAAAAATATCT +GTCTGCTCTGCTTTGTTCAAAGACTTTCTAATTCAACAGGAAGAATTAGCCCAGTTTAGC +TAGAAAATTCAACAGCCCTTACAAAATGGCCCTACTCTGCTTTCCCATATTTTTCTTTTT +CTTTCTTTTTTTTTTTTTGAGATGGAGTCTTGCTCTGTTGCTCAGGCTGGAGTGCAGTGG +CGCGATCTCGGCTCACTGCAAACTCCGCCTCCCAGGTTCACCCCATTCTCCTGCCTCAGC +CTCCCGAGTAGCTGGGACTACAGGCGCCTGCCACTACGCCCAGGTTTTTTTTTTTTTTTT +TTTGTATTTTTAGTGGAGATGGGGTTTTACCATGTTAGTCAGGATGGTCTCAATCTCCTG +ACCTTGTGATCCACCCGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCTACCG +CGCCCGGCCACCTTCCCGTATTTTTCTTTTCACTATTCCCCTATATAAATGGTTTATTTT +GCTTAATTTCTTTCTTGGTAAGTATACTGGCATGCAGAATTCCCCAGGGCCTTAGAACTA +AGGGAAATCTGGCTGTTCTCTGAGAATAATAATTACCAACACAGTGATTATAAAGCTGTC +TGTGGGTATATATTCAAGATTCTGTCTGTGAACATGTGATTGGTTATAGAATATCCAATA +CTCCAACTGAGATAACCTGGGCATAAATGGGATGTGGTCATTACTCAGTATGTGAAAACC +TGACTGACTACATACAGTTCTTAGAGAAAGCTGATAAATATAAAGTGGATGGTCAGCTTA +AAACAGAGGAAAAGATAATTTTAAGGGTAGAACTAGGATTTGAACCTGTAGCCAGTCAGG +GACAAAAGCTCCTGCTCTATACCCACCACAGCACAGTGCCACCCCTGAAAAAGATAATTT +TAAAGAGTTAGAGTCTAGCATTCTCCAGAGAGATGCTGAATTTGAGGAGATGACTTTATA +GTTCCTAGAGATATATGCTGCAGTAAGGAGGACCCACAAGGGCCTGGATTCACCCATTCA +TTCAACAATATTTACTGAGTTATCTACTATGTGCTGGGCACCAGTAGAACAAAGAACAGA +TGTGATTCTTCCGTGTATAAAGCTGTATTTGACTTGCACATTTATCAAGTAACCATCTGA +TAACTACTTAAGCTTTCTCAGCATGTTAGTACTAGGAAAGGCAGAGCCCTGGATGAGGGA +CTAAGCATTCTCATCTCTAAAGAGGACCTCCACTGTCAATTCACAAACCAACACACAGTA +AATATGTGTCAAAATGTTTCTACCATGTAAAGCAGAATTACTTTTTTGATATATTAGGCA +ATATTCCATTTTCTAAAATCCAATTCTGTAACTATTCCTTTCCCCTAAATTCTGCAAAAT +GGGCTATCCTACTATCTAAGATTTAAGAACAACTTTAGTTAATAAGACGCTTCAGACGTA +TCAGTGGAATAGGAACTCACCTTTGTTAAGTGCTATAGGTAAGACCAGATGTCTGGACAG +AACTGGGGGACTTGAAATATCAGCTATATCAATAAATCCCACTATTTCCAAATCTGAAAT +GAAGGAATCAACACAGAATTAATTCATTCTATGGAAAAGTACATTATTTTCCATGTATTA +CATTTCACAAATGCACTGTTTAGGTTGGGGTTTCAAATATGATGACTGGGAAAGTTATTA +GATTTGTATATGGAGTCGTCTAATAATTTGCATTTTAAGCTGCTCAGGAAATAATGATAA +CTGTCATTGATTTAATGAGTCTAAGTTATATGACAAAATCAGCTAAATTTTATTTTTATA +AGGTTAGGACCCCAGCCAAGGCAAAAACTGAAAGGTCTAATCCCTCTGTGTAGTCAGGGA +TGTTCAGGTCACCAGGGGGCATCATAGTCAAACACTTCCGCAGCAACTACACTCAGCCTT +TGAAGAATAAAGCTATTGTATTAAAAACATCTCTCTGAGAAAGAACTGTATTCTCTACAA +AACTAGGGTAAGCAGTCTAAATATGACAATGACTTCTCTGCTTTATAGACGCTGTAGTAA +AGACCAAAAGTATTTGTTGAAAACCTAAAATAAATAAAAATGAATGTTGTAACCAAAAGA +ACTTAAACATTTCGATTATATAATATAAAAACTTAAAAACAATAAAAATTATAAAGAAGA +AAAAGTCACTCATTATTCATAATCAAAGGAAATCTCTATTAATATTTTATTGATGTGCTT +TTCAGTCTTTCTTCTAGATTAATACCCATATTTTCAAAAGAATTTTTAAAAATCAGAATC +ATGGTGAACACCTTATATTTCTTTTTTCTTTTTTTGAGATGGAGTTTCGCTCTTGTTGCC +CAGGCTGGAGTGCAATGGCGCAATCTCAGCTAACTGCAACCTCCTCCTCCTGAGTTCAAG +TGATTCTCCTGCCTCAGCCTCCCAAGCAGCTGGGATTATAGACATGTGCCACCACGCCTG +GCTAATTTTGTATTTTTAGTAGAAACGGGGTTTCTCCATGTTGGTCAGGCTGGTCTCCCG +ACCTCAGGTGATCCGCCCGCCTTGGCCTCCCAAACTGCTGGGACTACAGGTGTGAGCCAC +CGTGCCCGACCCTATTTCTAAAATATTAGGAAGTGTGCTTCTCTGGAGATTTGCTGTCCA +TACCTCCCTTAGCTGAGTAATAAATGCATTAGTATAAGCAGCTAGATATTTTTCATTTGA +GTAGAAAAAGGTCTACTTTATTTTAAAGCAGTTTAGCTGCAAGAAAGATCTTCCACTAAG +AGTTTATATGGGAAAGAAAAGACCTATTCAAATTTACTCATCGAAAAAGGATGGGAAGGA +AGTGGAATCTAACTGTTATGAAGGCAACAAGACTTTTGGTACAACTTAATGTACTACTGT +CTAGTCACAGTAGAAGAGATGGATGCCTTGCTTCCAGAAGCTAAAGGCACAAAAAGTAAA +AAGACTGTTCACAGCCCCTCACTCCAACACTCCTTAAAAATCTGTATACCACAAACAATG +AGCATTCACTGAACATTTAATTCTAATCATTTATTGACTGAACAATTACCTATTGGGCAC +CTACTAAGTGTCAGGCACTATGCTGGACATCAAGGCTGTAATGGTGACTGAAACACTGAT +AATATCCAGCCCTAAAAGATTTAACATGCACCTAAGATTCAAGGAGTCCACCCACCAATA +GGAAGCAAGTCTCCTCTCCACTGCTCCTTGCTATTTTTGACTCTTCACTTTGCCAGTCTC +AGTTAAGCATAGTATTGGCAACACGAACCAGGTAAAAGCTGTGGTACATCACTTTCTTTC +AGTCATAATATAAGCAGCAGTGCTAGAAGAGTACACTATATCAGATCCAAGAACTCCAAG +ACCATCTGGTTGATTCTCCCTGCCTAGCCAATAAGAACTAGAGGAAGACTTCCCAGGGTC +ACATATCAAGAGTCATACTGCAAAGTATAGAAGCTAGCCCTTCTTATATGACCTTAATTA +TGATACTAATTAAGTTCAGTATGTCTATTAAGAATCATCTCAAAGATTTCAATGCTAGTG +AATACGGCTATGATTTCCAACTCTAATAATTCGTGGTTATAATTATCTAGGATTGGAGAT +CAACTGATGACCTTACCATAAAAGACCAATATTCTGCCACCCCTTAGGTAATGAATCTTC +CAATCCAAAGTGCTGATGACAACAGCACCCTAGTACAGGTTGAGTATCCCCTATCTGAAA +ATCTGAAATCCGAAATGCTCAACAATCCACAACTATTACACATGCACGAAGCTGACACGA +AGCTCAAAGGAAATGCTCACTGGAGCACTTTGGATTTTCAGATTAAGGATGCTCAATCAC +TAAGTAAAATGCAAATATCCCAAACCCCAAAAAATCTGAAATCTAAAGCACCTCTGTTCC +CAAGCATTTTGGGTAAGGAATACTCAACCTGTACCACAATATATATTTCTTTTCAACCTT +CCTAGACAGAGAAGAGAGTAAAAGTCACAAGTCAGAAGAAAGTAAGGATAACAGAGAAAC +TAAGAAATAAGTTTTTTTAAAAAGTTACCTGTGTTAATGACTTTAGGGATAGGATCAATT +TCTTCATCTACAACAAAAGGTTCTGGCCTGGGGAAGACTTGTACATCAGCAGTTAGGTGG +CCACACTTGAGAACAGCATGGAAAGGCGTATATGCCAAATCTATCAGTTTTCTAGAATAT +GATAATTAATAGTTATAGGAAGAGTAATACGATACATATGAAGTTAATTTTTCAGGACGC +AAGGGTTGTTTTCCTTTCAAGTTGGTTCCAAAACTAAGATCTGACCATCTGTAAAACAGA +ACAAAATCTGACATTTTTGGTGAGGAAATTTCAATTCTGAAAAGCCCAAGAGCAAGTTAA +TTTGAAATTTTGCTGAGTCATTATAAGGAAGTCAGTATCTACAGACAGTATAGATTTACT +TTAAAAAACCATTACTACCCATCACTTTATCTGAAAAATGTACAACTTGGGGAAAATGAA +ATGACACAATTAGGAACAGTAAAACAGATAGTCTTCCTGGATGTCAAATTATAATACTGG +ATTGTAAAGAAGGCAAAAGAGCTCTAAGCATATACTCACCCAAACATAGACTGTACATTC +TTCAAGCACAGGGGGCCATCAATAGTAAAAATCTGCCCTTCACCATTGTTTAAATCTATG +AGACGTTCAAGGCATTCCAAGGAATCGGTGCTCTGGAGCTATAAAGCAAAACAGATGACC +CTTAAAGTGGCTGGCACAAAATGCCAGATTATTCTCAGCTCACCAAGGTCAAAGCCATTA +CGATAACATAGGCAATAAATAACAGATGATTTTTTTAATAGCCAATGTGAGAAGAAAATA +ACAACAACAATTTTGACTCAAGGTTACCAAAGAGGAATGTTACGTAAAATAACACAGGTA +GAGCTATTTCATTCAGGAGTAGTTTTGCAAAGATTCTCAGAGGTGACCACAGTATTTACA +CAGCATCTTCCCTCCAAAGTGTTTCTAACGTCTTTTGGTGAGAACCATCATTATCTACAT +TTTACAGAGAGAAAAACTGAGGGGAAAAAAGGTTAAATCACCTTCCCAAATGAATGGGAA +AACCAAGAATTTAAGTGTTTAATAAAACGTGTATCAGAATAATGTTACTTTACTCTTCTG +TCAAAGTCAAAGCACACTCTTGTCAACATTTCTGGTGGAATGGACATAAGAATTCTATAT +AAGGGAAATGAACAACACCAAAAAGAACACCTTGACCCTTTATGCACCCATCAGCAGGAT +GGATAACAACTCCAGCTATGTTCCCCAGATGAGGCAACACTCTGAAATTTCAAAGAACAT +TTGAGACCCAGAATCTTTTCAAATAAAATACCAGCCTCAGCTGAAACCAATGGAGTTCAA +TGCTACAGTATATACAATATAGCACTAGTGGTATATACTGAAAAATAAACTAAGCTGTAA +AATATGCCTAATCAAACTAAAAACTTAGCAAAAGGTATTACCTCCTCCAAATTCGCCATG +CACATGATATATAACTTAGATGGGAAAGGAAAAGGTAGTGGAAACCTGTTGCTCTCACTT +CGTTGATTTTGAGTGGCTAGGGAATGTCGCAGTGACCCTCTACCAATGCCAAGACAGCCG +TCTGTCACCAGGACAACCTGTTTGTAAAAAGAGAGAGAGGAGGTTGTACATTAAATTACA +TATTTAACGCAGTCCCATTTAGCAGTGTTTTCACTGCTAGAAAGGGGCACCAGGGCTGGC +TATGGTGGCTCAAGCCTGTAATCCCAGTGCTTTGGGAGGCCAAGGCAGGACTGCTTAAGC +CTAGGAGTTTGAGACCAGCCTGGGCAACATAAGGAGACCCCATCTCTAAAAAAACTTAGA +AAAAAAAAATTAGCCAGGAGTGGTGGCATGCACCTGTGGTCCCAGCACGTTGGGAGGCTG +AGGTGGGAGGATCACTTGAGCCTGGGAGGTCAAGGCTGCAGTGAGCCATGGTCACATCAC +TGTACTCCAGCCTAGGCAACAGAGAGACTCTGTCTTTTTAAAACAAAACAAAACAAAACA +AAACAAAAAAAACAGGCCTGACATGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGG +CCAAGGCAGGCAGATCACTAGAGGCCAGGGGTTCAAGACCAGCCTAGGCAACATGGTGAA +ACCCTGCCTCTACAAAAAATACAAGAATTAACTGGGCATGGTGGTGCGTGCCTGCAGGCC +CAGCTACTTGGGAGGCTGAGGTGGGAGGATCACTTGAGCCTGGGAAGTCGAGGCTACAGT +GAGTATGCCACTGCAGTCCAGCCTGGGTAACAAAGTGAGACCCTGTTTGGAAAAACAAAA +TAAACCCTCAACCTGGCCCCGCAAAAAAAAAAAACAACAAAAAAAGGCACGAGAAAATTT +TGTGAGGTGCTAGAACCCCACTCCACATTATAGGATAAAGAATACTATATCTTAATTGTA +GTAGTGGTTATATAGGTGTATACATTTGTCAAAACTCAGTGAACTGTATACTTAAGATCA +ATGTGTTTTACTCTATTTCATCTAATAAAATATTTTTTAAAAGCTTGCCTCTGAACACTT +AAAAAAGGACAAAAACATTCACAACCAATTCTTACTTAATTGTATTAAAACTAGAACCCC +AACTCTTAGATAAGGAGTTGGTACCTAACATAACAATGTCAAATATGGAATGAAGATTCA +TTTCACATGTGCTCCTAGGAAGTACCAGCACAGTAGTCTGAACTTTGCCACTTTATTTTC +AAAGATGACAAACTCTACGCCTGGTCAACTAAAATGACACCTAGTTAGAATATGTATTTA +TAAAGGCTATTTAACCAGAAATATATAAGATCTTTAAAACGCATTCTTAACCTGTAATTT +GAAAAAACCAACAAAATATACCAACAATGGATAGTAATTGCAAAATCATTTTCCTTTTCT +TCATTGCTTCAGAATGATCCTGTGGTGGACAGACTTCCCATGCATCCCAGGAGAGGATTA +TTTTTGCTCTCCCTAGCCTAGTCCAGTAACTTGATAACAATAGGCCATTAAGGCAGTATT +TTTTTTTTGACAAGGAGACTCACTCTGTCACCCAGGCTGGAGTGCGGTGGCGTGATCTCA +GCTCACTGCAACCTCCGCCTCCCAGGTTAAAGTGATTCTCCTGCCTCAGCCTCCCGAGCA +GCTGGAACTACAGGTGTGTGCCATAAAGCCCACCTAATTTTTGTATTTTTAGTAGAGACG +GGGTTTCACCATATTGGCCAGGATGGTCTCGAACTCCTGACCTTGTGAACCGTCAGCCTC +GGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCGCCCGGCCCTTAAGGCAGTA +TTAAGTGGTGGCACTGTGTGAAATATCAAGATTGGCACTTACTGATAAAGCCCAAGAATG +CTTAATAGAGGTCCCCTGGAAGGATGTCATCTTTTGGCATGACAGTCAATTGACTACAAG +GCAATTTCCTTTTCTAGGTACCAAGAATTGCTATACAATGATTTACCTCCATCGGCTTTT +TCAGATGCTATGGGATAATGAAATATTTCACGTAATGTCAAAATGAAACAGACTTTACTA +AATAATAAAGACACAGTACAGCTGTCTAAAACCTTGGTTAAGGCTGGGTGTGGTGGCTGA +CAGCTGTAATCCCAGCACTTTGGGAGGTTGAGGCCAGAGGATCACTTGAGGCAAGGAGTT +CAAGACCAGCCTGGCAAACATGGCAAAACCTTGTCTACTAAAAATACAAAAATTAGCTGG +GTGTGGTAGTGCACTTCTGTAGGGCGTGATGGCACACTCCTGCAGTCCCAGCTACTCATC +AGGTGGCTGAGTCATGAGAATCATTTGAGCCCGGAGGCAGAGGCTGCAGTGAGCTGAGAT +CATGCCACTGCACTCAAGCCTGGGCGACAGAGCAAGACTCTGTTTCAAAAAAATAATAAT +AAATAAAAAACAAAATCTTGGCTAAAAATTCCACTTTTTTTTTTTTTTTTTAAGACAGAG +TCTCGCTCTGTTGCCCAGACTGGAGTGCAGTGGCACGTTCTCGGCTCACTACAAAATCCA +CCTCCCAGGTCAAGTGATTCCCCTACCTCAGCCTCCCAGGTAGCTAGGATTACAGATGAA +CGACACCACACTTAGCTAATTTTTGTATTTTTAGTAGAGACAGGGTTTCACCATGTTGGC +CAGGCTTGTGTTTAACTCCTGACCTCAGGTGATCTGCCCACCTCAGCCTCCCAAAGTGTT +GGGATTACAGGCGTGAGCCGTCGCGCCTGGCCAAAAATTCCACATTTAAGCAAGTTTGTT +TTATAGTAACTGATTATAAAAACAATAACCAGTAAACACCACCTCTACTACAATGTTTTT +TTTTTTTTTGAGACGGAGTTTCTCTCTTGTTGCCCAGGGTGGAGTGCGATGGCACAATCT +TGGCTGACCAGTGCAACCTCTGCCTCCCCGGTTCAAGCGATTCTCCTGCCGCAGCCTCCT +GAGTGGCTGGGATTACAGGTATGCGCCACCACGTCTGGCTAATTTTTTTATTTTTAGTAG +AGACAGATTCAGGCTTGGCCCCTTGCCCTCACGTTGTCTCAAATTCAGATTCTTCCTTTT +TTTCAAAAGAAGAAAATCATAAAAGTCAGAAGTCTGCATGATGCACAAGGTCTGGTTCTT +AAAATCTGAATTTCTCCTCTAAAACCAAAGAAGAAATAGCAAATGAAACTGTGCTACTTG +CTAGCTTTCAGTTCAGAAGATACTGACAACAAAACTTCATTTATTCACTATAATGTTAGG +AAATAAGACATCCTATATGCATGGATTTACCAAAATAAGTAATGCCTATAAGCTGAGATG +CCATAAAAAGCTTTTTTATTTCAGAAAAGAAATTGATCAAAAGGCATCTATTGATTTCTT +CAGCAAGTATCCACTATATTCTATAAAACAGGGAGGTTTTCACAAGAAAAAATGTTTTTG +TTGTTTTCTAAAGGTGAGTTTATTGAGATATAACTTACATGCAGTAAAATCACCCTTTTT +AGTATACAGTTCTATGAGTTTTGACAGTTGTATTCAGTCGTGTAACCACCCCCACAAACA +AGATAAAGAATAGTCCCAACACGTCCCAGATTCCCTCCTGCTTCTTTTGAGTCAATTCAT +ACCTTTCCCTGACTCCCAGGCAACTACAATCTTATTTTTTTTAAGACAGGGCCTCACTAT +GTGGTCCAGGCTGGTCTTGAACTCCTGGGCTCAAGTTATCCTCCCACCTTGGCCTCACAA +AGTGCTAGGATTATAGGTGTGAGCCACCATGCCTAGCTACAATCTTTTTTTTTTTTTATT +AATAAATAAATACTAGTGATGCTACTGACATTACTGAGGAATCCTTTGTTTGACCCCATA +ATGAAAAGTCACACACCAGGGTCCAGCCAACCATGGCCCACAGGCTAAATTTGGCCCACT +GTCTGTTTTTGTAAATAAAGTTTTATTTAAACACAGCCCTACCCATTCATTTACTTATTA +TCTATGGCTGCTTTCATGCTATAACAGCAGAGCTGAGTAGTTGCCACAGACACCTACAAA +GCCTAAAATACAAAAAAACTTGCGGACTCCTGTTGTAGACTATTATGATTTTTCTTTTAG +CAATGTTTCTGCTTTTTCCTTCAAAATATGCTACTACTTTTCAAAAGTATCTGTATAGAA +CAAATTTCCAGTTATCTTTTTCTGCTACTACTCTGCTCTGATTTGATACTAATGTGGCCT +ACTGTGGAGTCTAAGTAAAGAGCAACAGACTTTATGTTTGTTTGTTTTTGCCACACAGTC +TCGCTCTGTCGCTAGGCTGGAGTGCAGTGGCGCAATCTCGGCTGACTGCAACCTCTGCCT +CCCACGTTCAAGTGATTCTCCCGCCTCAGCCTCCAGAGTAGCTGGGACTACAGGTGCACA +CCACCACACCCAGCTAATTTTTGTATTTTTAGTAGAGATGGGGGTTTCACCATGTTGGCC +AGGATGGTCTCGATCTCTTGACCTGGTGATCCGTCCACCTCAGCCTCCCAAACTGCTGGG +ATTATAGGCATGAGCCACCGCGCCTGGCTAGATTTTATGTTTTATACTCCTCACTTTTTA +GACAACTCAGTTGAGATGGTTAAGTTTGCTGAATAAAGCTGGGCACAGTGGCTCACCCCT +GTAATCCCAACACTTTGGGAGACGAGGTGGGCGGATCGCCTGAGCCAGGAGTTTGAGACC +AACCTGGGCAATATGGCAAAACCTGGTCTCTACAAAAAATGTAAAAAATTAGCCAGGTAT +GGTGGCATTTGCCTGTAGTCTCAGCTACTCAGGAGGACGAAGTGGGAGAATCACCTGAGC +CTCGGTGGTTGAAGCTACAGTGAGCCATAATAGCTCCACTGCACTCCAGCCTGGGCAACA +AAGTGAGACCCTGTCTCCAAAAAAAAAAAAAAAAAAAAGTCTGCTGAATAATTGCATTGA +GATAATGAAGACAGGCTATATTATACTGATGTTTACAATTTTATCACTCAAAATTATAAT +GACCCCTTCCAGGGATTGTAGTTCAAAAATTCCACTGTGAGCCCTTTGTGTTTTATATAA +CAGTACTAGTTTGCAATAAGTCAATTTACTAGGAGGATGCTTTCCTTAAGGCATAACTTT +GCTGCTTTCTGAACACATTAGTGTTGATTTAGTACCTTCACTTAAGAAGATACCAATAGT +GTAAAATGTAGTTTGTAGAAATTACAATGCATGCTGTGTCAGAGCCTGAAGAAAATCGAA +GCACCTCAGTGGTTAATGTTGTTAACTTAGGGCAATGAAAAAGAATTGATCATTACCTGG +CAAGGAATTGCACCACCCCATTCTTGCTGAACGATATTGCAAACACCAACTAATGCAGAC +TCCAAGCAGGTTTTGTCATAATCATCCATATTACTTAGTGCTTCCTTATTGAATAAAAGA +TAAAATTGCTAGTTACTCTTTAGTTTTAATTAGGTATTAGAAAACAACATAAATTGTTCA +AAGTATGAATGTTACACAGGGGACACTGATGTATCTGAGAGCACCAAAGCATAGCTTCTT +AAAGAAAAATGCTAGAACAGACTTCTTCAACTATTAAAGATAGTTAAAAGAATTCCATTT +ATTCTATCCTCTTATCAGGTAAGAGTGAACAGTCCACCAAGTTTACATTTTTGTTAAGTG +GACTTTGAAGGAAAAAATTAAAAGGAACTTTTAAACACATCACAAAAATAATAACAAAAT +CTATTGAATATTAACTATGTTCTAAACACCATCCTAGGCACTTTTATGCATTTAGCTATC +ACAATAAAACTATAAGGTATAGATTATTAACCCTATCTTTAAATGAAGTAATTAAGGTAT +AGAAAGATTAAATAACTTTCCCAGGTCTCATGACTAAGGTGGCAGAACCTGGATTTGTAA +GTATGCAGTCTGACTTCAGGGCTCCTGGTCTAAAACATTACGTCTCACTCCTTATATAGC +AATTCTCTAAATTTCAGAACTGCAGAACATCAGAAATCCTTAGTTTATTCACCTGTAAGA +AAGTCAGCATATATACCAAAAGTTTAATATCCTTTTACAGGAAAAGAAATTTAAAAAAAA +TTTTTTAAGTCACTAATTTTTTTAAAAAAAGCTTTTAAGTCACTTAAAAAATCTGAGATA +AGGCCGGGCGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGACGCCGAGGCGGGCGG +ATCATGAGGTCAGGAGATCGAGACCATCCTGGCTAACACGGTGAAACCCCGTCTCTACTA +AAAATACAAAAAATTAGCCGGGCGAGGTGGCGGGCGCCTGTACTCCCAGCTATTCGGAAG +GCTGAGGCAGGAGAATGGCGTGAACCCGGGGGGCGGAGCCTGCAGTGAGCCGAGATCGCG +CCACTGCACTCCAGCCTGGGCGACAGCGAGACTCCGTCTCAAAAAAAAAAAAAAAAAAAA +TCTGAGATAATAAAAGGAATTATTTAACAAAATTTTGTTACTTACATTAAAAAATTCAAA +CTCTATTGATCTTGTATTTCTAAACCACCTAACAATTGTTAAAACTGTTCAGTTTAATTC +CACAAATGCTTCTTCTTTTTTTTTTTCCTTCTTTTTATTAAAAATAGAGACGGGATCTTG +CCATGTTGTCCAGGCTGGTCTCAAACTCCTGGGCTCAAGTGATCCTCTCGCCTTGGCTTC +CCAAAGTGCTGGGATTACAGGCGTGAGCCACCACACCTGGCCCACAAACACTTCTTGACT +GCTCACTATGGGTAAGACACTGTGTTAGGCACTGCTGGAAATATTATGAATATTATGATT +TAGAGATGTTGTCAGAAAGTAAATTCTAACATAACACAGAAAACACCTTTGAAAGATAAT +ATCTACCAACTGAGATTTAAAAATTATAATTTATTGGTATCAAAATCAAAGCTATTTGTT +GGAAAGGAAATATCATTTTGAATTACTCTAGAATAAGAAAGGGCTATTTTTTCATTTCCT +CAAGTTTTATGGGAGAGTAGAAAAAAATTAAGTGTTGAGCCTAAAGATCCTAAATTTTAG +GGAATGGAACACTACATCCTGAGATGCTCACTTTTCCACAGAGAATTCCAGAAAACCAAG +AGAGGAAAATAAGGGAACAACTCACAGCTGTAACTCATAGCTGTACCGAAGAAACAGTAG +GCATAAGACCTACTGGTTGTGAATTCTTGCTGTTTAGTTACACATATTAAGTACTCATAG +ACTTATTAAATAATGCCAAAGTTCTAAATATTCAACGCATTATAACACTGTTTTCCTCCC +AATAAATTTAGGCCCTGTACATACAATAACTTACTACATTTTGTACCTGTAGGGTATTAT +AATCTCTCGTGAAGGGGACCATCAACTCCCAAAGTGATGAAAAAACCACAAGTGCTGTAA +ATTCAAGCTTGTAATTTGTGGCCATGTGCTCAAACAGCATCGTTAAACCATGGGCTGCTA +GGTGCTTACGCTGGTATTCCTCGGACCCCTCAATAGACACAGGTCGGGTCATGGAAAGGG +ATACATCCATTACCACCACTGTCGGCATGATGAAAATGATCCCAGTGTTCCCAATCAGAA +TGCAAACAGACAGCTATAAACGAAGAAATGCTGCAGAAAATAAATACGTTCTTACATGTC +ATGGAGAGAAAATAATATTTTTCACCATAACTTTAACTAACTTCTCAGAAATTAGCAGAG +GCAAACACCATTTAAGTTGAGGTGAGGAATAATCTGTAGAGAACTCAGTGAGAGGGAAGT +GAGCAGCTTAGTTCATTGTAAGGACCACTCTTAGAATCACCCATTAAGTGACCATAAATC +AAGGACCATCTAAATATATCTACTGGAAAAAAAAAAGCCCTGCTAAATTCAGGTAGCCCT +TAACTTTCACACATTCGACTTTTATGCAACTTAATAAACTCCCACATCTCCTAACACTTA +ATTTACTGAAGAACATTTCTAGTTGTCATATGTTGGTGCTATTTGACAAACAACCATTGT +TTTTTGGCACTGTCACAACCTTTTTGCAGTATTACTGCATGTGTTTAATTATTTTGTTGG +TTGGTGCTCTTGTTTTAGTAAAATGAATGCCAAATATAAAAATGAAAGGACTAGTAAAGT +CATAAACCAAATTAGACAAATTGGAAATCATTACACATAACAAAAGTAATAAACTGTCAG +CCTCAGTAGTATTCATTGTACATAAACTGGCCAATGGTGCTTCAACTGTGAAGGAAAAGA +ACAAAATTAAAGAATATGTAAGGTCGGGCACAGTGGCTCATGCCTGTAATCCCAACACTT +TGAGAGGCCCAGGTGGGCGGATCTCTTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAATA +TGGTGAAACCCTGTCTCTACTAAAAATACAAAAATCAGCCAGGCATGGTGGCTACTTGGG +AGGCTGAGGCACGAAGATCCCTTGAACACAGGAGGTGGAAGTTGTAGTGAGCCGAGATCG +TGCCACTGCACTCCAGCCTTCCAGCCTGGGTGACAGACGAAGGCTCCATCTCAAAAAAAA +AAAAAAAAAAAAAAAAATTTATACAGCTGGAATTATCTCATGAAATTGGGTAGAAAAGTC +AAAATGTACAAATGGAGTTATTCAAAATTATGGATTGAGAATTAGCATAAAGAAAACATT +TTGGTGCTCAAAAATAAAAAAGTTTACAGATACACAGACCTGCTCATGGGTATATAGCCT +GCTGCTACTCTATTATTAAGCAAACTGTAGGCTACTGACATGATGAAATATCATAAAACT +ATAAATAAATGACATATGTACTACAGATATCAGAAATACTTATAGAAAGCATTAGTAACT +GAGAAAAGCAGGCCCCAGAACTGTATTATACACTGCTTACAACTTCATAAAAATCATAAT +GCAAATATACAATTAGAGAGATTAGGTGGATATAAACAGGTTAGAAATTTAATGTTCACA +ACTTTCTTTTTTGGGATTAACTTCAAAACATTTAACAGTAGCCAGATTACTTGTTTAAGG +ATGGTGCCCAGCTGCAAATGTGTCATATTCTAAAATTCCATTTGTTCTTTTTTGTTTTTG +AGACGGAGTCTTGCGACATCTGTCGCCCAGGCTGGAGTGCAGTGGCGCGATCTCCGCTCA +CTGCAAGCACCGCCTCCCGGGTTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCCGG +GACTACAGGCGCGAGTAGCCAGGACTACAGGCGCGTGTCACCACACTCGGCTAATTTTTG +TATTTTTAGTAGAGATGGGGTTTCACCACATTGGCCAGGCTGGTCTCGAACTTCTGACCT +CGACATTGGCCAGGCTGGTCTCGAACTTCTGACCTCGTGATCCACCTGCCTCTGCCTCCC +AAAGTGCTGGGATTACAGGCGTGAGCCACCGCGCCCAGCCAAAATTCCATTTGTAAGTAG +GCTGTTTCGAACTCAGAATACACTGGTTCATGGAAACAATGTTTACAACTCAGGTTGTAA +GCATAGGCGTAAAAGAAGAAACTGAAAGTTCCTGAAGGATGGTTCACTCAAGCAGTATAG +GCCCGACTGAAAAAAAAAAAGTGAGGTCCTGCACAATATTGGTTCAACTACACTATATTA +GACCATAACATACGCTCACTAAGGGCAGGGACCATGCCACATTTTGCCCATGATGTCTCC +TCAAAACTTATCACAGTAACTGGCACATAGTAGGTGCCCAACAATTTGATAACAACTGAT +GAACTACCCCTAAATCACCAGATATACCATATATTATTTAGCAAAATACATTATAAATGT +TAACTCTGGACACCAGAAACACATTTCCTCTTCTCCTCATTCAAGCAGACATATGGGGGA +CTCCCTCACGTCTGCCCAGCTCCTGTGGTAGTCCCATTCATGCAGGGAGGCCTTTTTACA +AGTTGAGGATCATGAGGAGTACTGCCCTCACCTCTTAGGAGAATGGGAGGAAACAGTTTA +CACAGACTTAGATCAAATACAAAAAAGCACTTTCAGCCCGTGAAATCTGCTGTTGACAGT +GATGACAGCTGGCAGTCTTGCCTTCTCTGAAGACACCTCTGGAGCTGGCTCTTTCTCCCA +AGTGATGCATTTGTGTCGACTCCCAAATGCACCTCATTAACAGTTACAAAGTCGTGGGAG +ATCAATTTAGTACTCAGGTTGGAGTAAAGGAGGGAACTGAAAGTTCCTGAAGGATAGTTC +ACTCAAGCAGTATAGGCCTGATTAAAAAAAAAAAAGGCCAGGCACGCCTTTAATCCCAGC +ACTTTGGGAGGCTGAGGCGGGCAGATCACCCGAGGTCAGGAGTTCGAGACCAGTCTGACC +AACATGGTGAAACCCCATCTCTACTAAAAATACAAAAATTAGCCAGATGTGGTGGCGTGC +GCCTGTGGTTCTAGTACTTGGGAGGCTGAAATAGGAGAATTGCTTGAACCCAGGAGGCAG +AGGTTGCAGTGAGCCGAGATCGCGCCACTGCTCTTCAGCCTGGGCGACAGAGCGAGACTC +CGTCTTGGGTGGGGGGGAATCCCTGCCCACCACAGTCTACCAATTTTGTGAGCACAACAC +TATGTATTCCTCACTTGGGTGGATTCTGAGCCCCCAAGTCTCCCACCCCCACCCCCTTCC +CACGTGTACTGTTCAAACAACTAGGGCTCTTCTTTCTCAGGAACAGTCTGAGAAATAGGC +CCTAGCCACCTATTTGGCCTTGAATACCAAGTGTCCATCAGCTAGACGTTTGTAATTCTT +CCCTGAAGGTGATAATTAGCTCATTCATAAAGAACTGATTCTCAGCAGTCTCGCTCTCAA +AGCAGGATTCTACCTGAATTTCTAGTGCCTCACCTGCTCTTTGGCTTTCCCGTCAGCCTC +CGGGAGTCCCTCCCCAGTTCTCAGATATAATTTCATCTCTAAAAGTCCAGACTGAAAATC +ACATCTGGGAGATGTATTTTTACCTTAAAAATCAGTCAAGAAAATGTGGGATCTGGAAGT +CTCTCTTGGAAAGAGGGGGCAGAGGGGAGCTGAGCAGAGGGCGAAATCGTGCAGTTTACG +CGGAGCTGGGGACCCCGAGCCTCAGAGCGAGGGGAGGCCGGGAGCAGCGCCCCGGAACTG +GCGCCTCACAGACAGCGCGGGGCGGCCGCCACGGTGGCGGGAAGGCCAAGCGCTGGCCCT +GGGTTGTTCTTCACCCATAACCCCTTCACCTGTAACCCCAACAAGCAGCGAAAGGCAGTC +CCGGGCCCTCGGCCTCCCCACTCACCCCGTGCCCATCGCCGGACACAGTCCGTCGGCATA +AACTTTCCGTCGGCATAAACTTTCCGTCCGCGCGCCACAGCCGGAACTATAAGGCCGCGC +GACAGAAGGGAATCCGGCGCCTGCACTCCGCGCTGGGCGGGGCGGTCCTTGGAGAGCTTC +AGGGTCGCCCGGGCAGGGTTCTGGCTCATCCCGGAGGGACGCTAGGGGGCGCGGCCT diff --git a/test/csq/ENST00000573314/ENST00000573314.fa.fai b/test/csq/ENST00000573314/ENST00000573314.fa.fai new file mode 100644 index 0000000..192aeb5 --- /dev/null +++ b/test/csq/ENST00000573314/ENST00000573314.fa.fai @@ -0,0 +1 @@ +15 32577 25 60 61 diff --git a/test/csq/ENST00000573314/ENST00000573314.gff b/test/csq/ENST00000573314/ENST00000573314.gff new file mode 100644 index 0000000..6225038 --- /dev/null +++ b/test/csq/ENST00000573314/ENST00000573314.gff @@ -0,0 +1,28 @@ +15 ensembl_havana gene 21 32557 . - . ID=gene:ENSG00000138614;Name=VWA9;biotype=protein_coding;description=von Willebrand factor A domain containing 9 [Source:HGNC Symbol%3BAcc:25372];gene_id=ENSG00000138614;logic_name=ensembl_havana_gene;version=10 +15 ensembl_havana NMD_transcript_variant 21 32404 . - . ID=transcript:ENST00000573314;Parent=gene:ENSG00000138614;Name=VWA9-001;biotype=nonsense_mediated_decay;havana_transcript=OTTHUMT00000256861;havana_version=3;transcript_id=ENST00000573314;version=1 +15 havana exon 21 927 . - . Parent=transcript:ENST00000573314;Name=ENSE00001522374;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001522374;rank=12;version=3 +15 havana three_prime_UTR 21 927 . - . Parent=transcript:ENST00000573314 +15 havana exon 3222 3287 . - . Parent=transcript:ENST00000573314;Name=ENSE00003529647;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003529647;rank=11;version=1 +15 havana three_prime_UTR 3222 3287 . - . Parent=transcript:ENST00000573314 +15 havana exon 6038 6156 . - . Parent=transcript:ENST00000573314;Name=ENSE00003589575;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003589575;rank=10;version=1 +15 havana three_prime_UTR 6038 6156 . - . Parent=transcript:ENST00000573314 +15 havana exon 12866 12999 . - . Parent=transcript:ENST00000573314;Name=ENSE00003515554;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003515554;rank=9;version=1 +15 havana three_prime_UTR 12866 12999 . - . Parent=transcript:ENST00000573314 +15 havana exon 14696 14840 . - . Parent=transcript:ENST00000573314;Name=ENSE00003647901;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003647901;rank=8;version=1 +15 havana three_prime_UTR 14696 14840 . - . Parent=transcript:ENST00000573314 +15 havana exon 17001 17093 . - . Parent=transcript:ENST00000573314;Name=ENSE00003653848;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003653848;rank=7;version=1 +15 havana three_prime_UTR 17001 17093 . - . Parent=transcript:ENST00000573314 +15 havana exon 19589 19731 . - . Parent=transcript:ENST00000573314;Name=ENSE00003663634;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003663634;rank=6;version=1 +15 havana three_prime_UTR 19589 19731 . - . Parent=transcript:ENST00000573314 +15 havana exon 20140 20258 . - . Parent=transcript:ENST00000573314;Name=ENSE00003617560;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003617560;rank=5;version=1 +15 havana three_prime_UTR 20140 20258 . - . Parent=transcript:ENST00000573314 +15 havana exon 21042 21197 . - . Parent=transcript:ENST00000573314;Name=ENSE00003657631;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003657631;rank=4;version=1 +15 havana three_prime_UTR 21042 21197 . - . Parent=transcript:ENST00000573314 +15 havana exon 26397 26504 . - . Parent=transcript:ENST00000573314;Name=ENSE00003616634;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003616634;rank=3;version=1 +15 havana three_prime_UTR 26397 26504 . - . Parent=transcript:ENST00000573314 +15 havana exon 28427 28710 . - . Parent=transcript:ENST00000573314;Name=ENSE00003667579;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003667579;rank=2;version=1 +15 havana three_prime_UTR 28427 28710 . - . Parent=transcript:ENST00000573314 +15 havana three_prime_UTR 32064 32225 . - . Parent=transcript:ENST00000573314 +15 havana exon 32064 32404 . - . Parent=transcript:ENST00000573314;Name=ENSE00001522376;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00001522376;rank=1;version=2 +15 havana CDS 32226 32399 . - 0 ID=CDS:ENSP00000458470;Parent=transcript:ENST00000573314;protein_id=ENSP00000458470 +15 havana five_prime_UTR 32400 32404 . - . Parent=transcript:ENST00000573314 diff --git a/test/csq/ENST00000573314/ascii-art.txt b/test/csq/ENST00000573314/ascii-art.txt new file mode 100644 index 0000000..36066f9 --- /dev/null +++ b/test/csq/ENST00000573314/ascii-art.txt @@ -0,0 +1,16 @@ + +rev strand +c .. CDS +u .. UTR +. .. outside the transcript + +32388 32399 +89012345678901234 +ccccccccccccuuuuu.... +GTCCGTCGGCATAAACTT-----------------TCCGTCGGCATAAACTTTCCGTCCGCGCGCCACAGCCGGAAC ref +GTCCGTCGGCATAAACTTTCCGTCGGCATAAACTT alt + +G-----------------TCCGTCGGCATAAACTTTCCGTCGGCATAAACTTTCCGTCCGCGCGCCACAGCCGGAAC ref +GTCCGTCGGCATAAACTTTCCGTCGGCATAAACTT alt + + diff --git a/test/csq/ENST00000573314/ascii-art.txt-l b/test/csq/ENST00000573314/ascii-art.txt-l new file mode 100644 index 0000000..36066f9 --- /dev/null +++ b/test/csq/ENST00000573314/ascii-art.txt-l @@ -0,0 +1,16 @@ + +rev strand +c .. CDS +u .. UTR +. .. outside the transcript + +32388 32399 +89012345678901234 +ccccccccccccuuuuu.... +GTCCGTCGGCATAAACTT-----------------TCCGTCGGCATAAACTTTCCGTCCGCGCGCCACAGCCGGAAC ref +GTCCGTCGGCATAAACTTTCCGTCGGCATAAACTT alt + +G-----------------TCCGTCGGCATAAACTTTCCGTCGGCATAAACTTTCCGTCCGCGCGCCACAGCCGGAAC ref +GTCCGTCGGCATAAACTTTCCGTCGGCATAAACTT alt + + diff --git a/test/csq/ENST00000573314/incorrect-insertion-overlap.txt b/test/csq/ENST00000573314/incorrect-insertion-overlap.txt new file mode 100644 index 0000000..12dd09a --- /dev/null +++ b/test/csq/ENST00000573314/incorrect-insertion-overlap.txt @@ -0,0 +1,3 @@ +32388 GTCCGTCGGCATAAACTT GTCCGTCGGCATAAACTTTCCGTCGGCATAAACTT frameshift|VWA9|ENST00000573314|NMD|-|4DCVRRWARGEWGGRGPGTAFRCLLGLQVKGLWVKNNPGPALGLPATVAAAPRCL*>4ESLCRRTVSGDGHGVSGEAEGPGLPFAACWGYR*|32388GTCCGTCGGCATAAACTT>GTCCGTCGGCATAAACTTTCCGTCGGCATAAACTT +32388 GTCCGTCGGCATAAACTT GTCCGTCGGCATAAACTTTCCGTCGGCATAAACTT frameshift|VWA9|ENST00000573314|NMD|-|4DCVRRWARGEWGGRGPGTAFRCLLGLQVKGLWVKNNPGPALGLPATVAAAPRCL*>4ESLCRRTVSGDGHGVSGEAEGPGLPFAACWGYR*|32388GTCCGTCGGCATAAACTT>GTCCGTCGGCATAAACTTTCCGTCGGCATAAACTT + diff --git a/test/csq/ENST00000573314/incorrect-insertion-overlap.txt-l b/test/csq/ENST00000573314/incorrect-insertion-overlap.txt-l new file mode 100644 index 0000000..12dd09a --- /dev/null +++ b/test/csq/ENST00000573314/incorrect-insertion-overlap.txt-l @@ -0,0 +1,3 @@ +32388 GTCCGTCGGCATAAACTT GTCCGTCGGCATAAACTTTCCGTCGGCATAAACTT frameshift|VWA9|ENST00000573314|NMD|-|4DCVRRWARGEWGGRGPGTAFRCLLGLQVKGLWVKNNPGPALGLPATVAAAPRCL*>4ESLCRRTVSGDGHGVSGEAEGPGLPFAACWGYR*|32388GTCCGTCGGCATAAACTT>GTCCGTCGGCATAAACTTTCCGTCGGCATAAACTT +32388 GTCCGTCGGCATAAACTT GTCCGTCGGCATAAACTTTCCGTCGGCATAAACTT frameshift|VWA9|ENST00000573314|NMD|-|4DCVRRWARGEWGGRGPGTAFRCLLGLQVKGLWVKNNPGPALGLPATVAAAPRCL*>4ESLCRRTVSGDGHGVSGEAEGPGLPFAACWGYR*|32388GTCCGTCGGCATAAACTT>GTCCGTCGGCATAAACTTTCCGTCGGCATAAACTT + diff --git a/test/csq/ENST00000573314/incorrect-insertion-overlap.vcf b/test/csq/ENST00000573314/incorrect-insertion-overlap.vcf new file mode 100644 index 0000000..446d24c --- /dev/null +++ b/test/csq/ENST00000573314/incorrect-insertion-overlap.vcf @@ -0,0 +1,6 @@ +##fileformat=VCFv4.2 +##contig= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO +15 32388 . GTCCGTCGGCATAAACTT GTCCGTCGGCATAAACTTTCCGTCGGCATAAACTT . . EXP=frameshift|VWA9|ENST00000573314|NMD|-|4DCVRRWARGEWGGRGPGTAFRCLLGLQVKGLWVKNNPGPALGLPATVAAAPRCL*>4ESLCRRTVSGDGHGVSGEAEGPGLPFAACWGYR*|32388GTCCGTCGGCATAAACTT>GTCCGTCGGCATAAACTTTCCGTCGGCATAAACTT;type=ENST00000573314:65903458-GTCCGTCGGCATAAACTT-GTCCGTCGGCATAAACTTTCCGTCGGCATAAACTT .. this is incorrect, see ascii-art.txt diff --git a/test/csq/ENST00000593942/ENST00000593942.fa b/test/csq/ENST00000593942/ENST00000593942.fa new file mode 100644 index 0000000..2214323 --- /dev/null +++ b/test/csq/ENST00000593942/ENST00000593942.fa @@ -0,0 +1,345 @@ +>19 19:7541741-7562355 +CCTTCACCCCTGAGCCAGGCGCCAGCACCACAATGTTTAATTGATTCCCGTTCCAGCTTT +CTCAAGGCACGACAGGCCCCCTCTTCCTCATCTTGATTTGGATACAAGACGCCAGCTGGC +AGGCAGGAGGTGCTGCTGAAGCCCTGCACGGCCCCTGAAAACTGTCACGGCTCAGGAGCT +CCAGGCTGAGGCCTGGGGGACCTCGCATCAGTCCCTCCACCCACCCTGCCCATGGGTTTC +ACCACAGGCAGCTCCATGAGAGCCCCGGCCCCTGCCCTGGCGGCTTCTGCTTTGCGGGAA +GGGCCCTCCGTGGGCTCTGGCTGTGTCCCTGTGCTCTTCCGGCAGTGTCAGGGGGTAGTG +GCCTCGGCCTGGCCGCCGGCCCGGGCCGCCTGGTACATGCTGAGGATTGAGGAGATGGTG +CCCATGAGGCCCACTAGCCACGGCGGGAAGCGGCCGGCCCACAGCACGCCCCGGGGCAGC +CAGTGCACGGCGTTGGCCAGGTCGGCCAGGTTGCTGAGAAGTGACAGCGCCTCCGACTGC +ATCTGCGCCTCCATGGCCCTCCGCTTGCCCCGGGGCAGCGGGCTGTGGGGCAGAGAGGGG +CCGCTTACACTCACGCTCACACCTGCCTGCCCTTCCCAAGCCCCTGAATGCCCTGTGTGG +CCTGGCAGCCCTGAGCCCCTGCCTGTGAGTGGGAGGAGCTGGCAGGACTGAGGTGGCCTC +CCTGACCATCCACAGAGACTGAGTCCCCATCACCCCCCCGACCCAAGCACGAACAGGGCA +GGAACCCGGGTCCAAGTCCTCAAATCCACACCTCACTCCTCGTCCTGAACACCCAGAGAT +GGGGATTCCTTGTGAAAAACAGAAAGCACAAATGCACTTTGGGAGGTGTGGAGGGAAGGG +GGAACCCCCAGGAGCGTGGCCTGTGCCTGCCCGGCCTTTCTTTATCAGGATGACACAGTG +ACGATAAGCCTGGCCAATATGGCGAGACCCCATCTCCACCAAAAAATAAAAAACAAAATT +AGCCAGGCGTGCTGGCCCGTGCCTGTAGTCCCAGCTACTCGGGAAGCTGAAACAGGAGGA +TCAGTTGAGCCCAGGAGGCAGAGGCTGCAGTGAGCCAAGATGGCACCACTGTGCTCCAGC +CTGGGCAACAGAGCAAGACCCTGTCTCAAAAAACAAAAAGAAAAAGCAACAGTAACAATG +GCCATGGCCTTCGGGAAATTGATCATTCTCTCCTGCTGGGGGCGCAGCCATGAAGGCTCA +GCCCTGGAGTCCCCGCTCAAGCAAGCCTCAGTTTCTCCATCTGTAAAAGGTACCGCCACC +CACCAGAGGCTGTGATGACTCCCCCATGACCTGAGCACAACAGTCCCCAGCATGGGCCTG +CACAGGGGTGGCTGCGAGCCGGGATCCCACGCCTGCTGGAGGGAGTGGGCCTCCCTGCTG +GGTGATCACGGGCTCCTACCTGGTGAAGGGCGCCGTGGGGCTCCGCAGCCTCTGTCTCAG +TTTCAGCAGCATCCACAGGGACCTGCAGCACCAGAGCCCGAGGGAGGATGCCCCGGCGGG +GAGCAGGAGGGTTAGCTCCACAACGCTGGCCCCGGACATACAGTCTGGGACAGGTGCTGC +ATCTCGGATAAACGGCCTGCCCTCTCCCTGCCCCCACAGTCCCACACCCTCCTGGCTGTG +CCTCATGCTCCCGGGGACTCATCTCTAACACGGCCCCGTCCCACCCGGGACATCGTCCTG +CACTTCTGACGTGGCCATCCAGGGCCTGGCCCAGCCTCTGCAAACCACTGGCAAGTGCTC +AAAGGAACATCAAGCCCCGTGAGGTGTTCACAGCCTGGCAGGGAGTCCTACACAGAAAAG +GATGCCAAGAGGCCCGCAGTTGGACAGGCGTGGGGACGCCGTTTCCCCTCCGGGCCTCAG +CTGCCTTGTCTGCTCTGTGTGGAAAGGTCCAAATCAGTGCCATGCCAGCACCCCCTGCAC +ACACACCCCGGACATTGGCTGGACCTGTCTGGATGATCCCCTGGGCCCCCAGGGCTGGCA +TCTGCAGGCTGAGGAAGGGGCTACCCAGTGGGCAGCCTCTGTGCTCCCAGCAGGCTCTGC +AGCCGTGCATGGCACCCACCCGGGCCAGTCCACCAGGCACCTGCACTCTCCAGCCTCGGC +CGTGGGGTGTGCCGGGTTGTGACTGTGACAGAATGGGCAGGGCCTGGTCACAACTCCTCT +GGCCACTGGGTACCCAGGGTGCAGGATGCAGGATAGCGCCAGTGGCACAGCAGGTGGGAG +CCTCCTGGGGGGCTAGGGAAAAACACTGATTCCTGGGCTCCCCAGACCCACAGAATCAGA +AGCTCTGGGCCAAGCGCGATGGCTCACACCTGTAATCCCGGGACTTTGGGAGGCCAAGGC +CGGTGGATCACCTGAGGTCAGGAGTTCAAGACTAGCCTGGCCAACATGGTGAACCCCTGT +CTCTACTAAAAATACAAAAATTAGCTGGGGGTGGTGGTGGGCGCCTGTAATCCCAGGTAC +TCGGGAGGCTGAGGCAGGAGAATCACTTGACCCCGGGAGGTGGAGGTTGCAGTAAGCCAA +GATCGCACCACTGCACTCCAGCCTGGGCGACAGAGGAAGACTGTGTCTCAAGAAAAGAAT +CAGAAGCCCTGGGCGCCGGACCCAGGCATCTCCATTTAGCAACCTCCTGGCTGATGCTCC +GGCAGCCCTGGGCCTTAGGGCAGATGTCTGGTCATGATGAGCACACATGGAATGCTCTCC +ACCCACTCCCCCTGCTCACTGCAAATCCAGAGAAATGATGAAAAACCACATGCCCGAAAC +AAGAATGCCGCAGCAGGCGGGGCACACAGGACTTCGATGGCCGTGAAACAATTCCATTTG +ATTCTGCAAGGGGGGACACGTGTCAGTGTCCAAACCCATAGGATGCCCAAAACCTAGCGT +GAACCCTAACGTGAGCTACTCACTTGGGGTGATGATGGATCCATGGAGGGGCATCAGTTG +TAACAAATGCACCATGTGGATGCTGCCAGTAGTCGGGGAGGCTGTGTGTGGGGGTATATG +GGAGCTCTCTGAACGTTATGCTCAATTTTGCCATGAGCCTAAAACTGCTCTAAAAAAATA +AAGTCTGGGCCGGGAGTGGTGGCTCACGCCTATAATTCCAGCACTTAGGGAGGCCAAGGC +AAGTGGATCACCTGAGCCCAGGAGTTGGAGACCAGTCTGGGCAACATGGCAAAACCGTGT +CTCTACAGAAAAAAAATTACAAAAATTAGCCAGATATGGTGGCACAGCCTGTGGTCCCAG +CCACTCAGAAGGCTGAGGTGGGAGTATTGTTTGAGCCCAAGGGGCGGAGGTTGCAGTGGG +TCAAGATTGAGCCACTGCTTTTCAGCCTGTCTCAAAAAAAAAAAAAAAGTTTATTTAAGC +AAAAAAGAAAGGAACCAAGGCTGCCCCTAAAATACAAACCAGAGGTCACGAGGCACCCAG +AGGAAGGTGGCGGAAGAGAGGCTGTGAGCCAAGGCCCCCCTCTGACCGGAGCCCCAGGAA +CATCCAGGCTGGGCCCAGGCACCCTCCCCCAGGTCTCCCAGCACACAGGGAAGGCCAGCA +GCACAGACACCGCTGCCTCCAGGGGCCATGGCCATGAAACATGACCCTTTTGAGACAGCC +AAAATGCACAGGCAGGGTATTAGGTCAAAGGCTGGAAAAGAACCACCCAAGCTTGAACAG +TGGGAGTCTGGGTTGGATTGTGGGTAATTCGAATCTTCTACTCTGAGGTTTATCTATTTT +CCAGATTGTCTACGGTAAGCATGTAATTAGGACATCTGTGCCGGGGGGAAAACAAGAACT +ACTGAGAGTCAGAGCCTCGACCAGGGACAAGCAAAGCTTCCCCCAGAAAAAGGACACAGC +CTGCCTGAGGCTGGGGGCAGCCGCACCTCACCCCAGCGATCTAAGAGCCCTTCACAGCCA +CTGAAACATGGAGACCAGGGGGCCCAGCTCCTGCTGGTGTTTTCAGGGGCAGGGGATTCT +GACTCAGCGCATTTGCAAAGAGGAAAATGTTTGGGAGGAAACCATTACTAGAAAGTTCTA +GAAACTATATGGTTTTTTGGAGGCACAGAACTAGTCAGGAAACTGCTGACTGTTTTCTCT +GGGGTGTCGGCTGACAGCAACGCCAGCAAGACTCAGGGACCCGGGTAAAGGCCACTCCGC +TGGCTGCTTCTCACAGGCCCTGGAGTTACTTCTTCTTTCTAAGTGTGGTCAGCAGAGTCA +TGACCCCTTCTAAAATGTCCATGTCCTGAACCTGTCAACATGTTCACCTCCAAGGCAAAG +GATATTTTGCCGATGGGATTAAGCTAAGGATTTTTTCTTTTTTTGACACGGAATCTTGCT +CTGTCGCCAGGCTGGAGTGCAGGGGTGTGATCTCGGCTCACTGCAACCTCCACCTCCCCA +AATTCAAGCAATCCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACAAGTGTGCACCAC +CAAGCCCAGCTAATTTTTTGTATTTTTAGTAGAGACAGGGTTTCACCATGTTGGCCAGGC +TGGTCTAGAACTCCTGGGCTCAAGTGATCCACCCGCCTTGGCCTCCCAAAGTGCTGGGAT +TACAGGCATGAGCCACCACGCCCAACCTAAGCTAAGGATCTTGAGATGGGGTATTACCCT +GGATCATCCAGGTGGTCCCCATGTCATCATAGGGGTCCTTATAGGAGGGAGGAAGGAGGA +TGAGGGTCAGGGAAGGAGGTGTGACGCTGAAAGCAGAGGTCATGCTTGGAAGATGAAGGA +AGGGGCCATGAGCCAAGGAATGTGGGTGGCCTCCAGAAGCTGGAAAATCCAAGGAAACGG +ACCTCCCCCTGGGACCTCCAGAAGGCATCAGCGCCTGCTGACACTAGCCCAGGGAGTGTT +CTGACTTCCAGCCTTCAGAATCCTAAGATAAGAAGTTTCTGTTGCCCAGCACTACAGAGT +TGTGCTAATTTGTTCCGACAGTTATTCTAAACAAATACACCCACAAAAGGAAGAAACAAC +AAAACCTCCAAGGAAAACTCTAAGAGGCAAAGACCCACCGCAGTCTGAAGCCTGTGCTGT +TGCTGGGGCCGCTGCCACTTTGCTAAGGAGGCACCGCCCAGGGACCTTGGGTGCTCCCTT +CTGGCCCATGCCACTTACCTGGCAACCCCCAGGAGCAGAGAGAGGGCCCACAGGGTTGTA +CTCAGCGTCCACCACCGAGAAGAGTCCACGTGGAGGACCCGGGCATCAGCCGCCCAGGCC +ACGTGCTCACAGGGGTAGTAGAGCTGGTCAGCCAGGTTCCCTAGGACGGAGACACAGCGG +ACAAAGGCGTCCTCCTCCTGCAGGACCAGGAGCAGAGGGGGCCTAGGGTCAGACTTACCC +ACTGCCCATTTTAGCACCGTAGCCATGCCAGGTGGCAGAGAGCTATTTCCTGACCCCAGT +CCCTGGGCCGTGTCCAGGCCTGGCAGGCCCCGCGGGAGAAAGGCTCTGGGGCTGGGGTCC +CCGCACAGGCCTGATTTCTGTGTCTCGGCAGCACGGTGCTCAGTGCCCCTTGGAGGGAGG +CTCTCAACGCAGCTGTGCAGTGCAGTCCTCTGCAGAGCTTCAAAAACCCCATGCCCAATG +CCAGCCGTGAGGATTCTGCCTCACTCAGCCTGGGGCAGGCCCCAGTACCGGGAATTTTCA +CAGGGAATTTTCACATTCCCAGGGGATTCCCAGGCCAAGTTGGGAGCCCTGTGTCAGAGC +CTTCCTTCCCAAAGGCTTCCAGTTCCTGCACAGGTGGGGACCTCTGTTGCCAGACTCTAT +GCAGGGAGCATGAGGTGGCCCGCAGCGAACCCTGACCAGGCTGAGATGGTGTGCCAACCC +TTGGGCCACCGCACGCCCACTGCTGACCACGCGCCAGGCACAGTGCGGCAAGGCTCATGG +CCTCCCTCAACTCCGAGCAAGTTACAGACGGCCACGCTGAGGCTCTCAGGGAAAGCCGCT +GGCCCCCAGTTCCGGCAGGGATGGGCCTCCAGGCCCTCGAATTGCAATGCACACGCGGGC +TCTCGGTCCTGCACAGTGCCCATACCCTCTGCCCCAAGTTCTTAATCACACGGCCTAGAG +CCAGCGAGGCAGGACCAGTTGAGGCTGTAGAAACCAGCGCTGAAGCCTGGTTTCTGGGAC +TGGAGCCCCGCAGCCAACCGGGGGACCCGCCCCCTTGGGACCCCACCCCCCTTGGGACCC +CGCCCACCGTGACCCCGCCCCATCGGAGCCCCGCCCCCTCTACCTTTATCCTCCTTGTTA +CCTGCCACACCCTTCCCCTCCTCTCTGACTTCCCAGGAAGCTCCTCCCCGCCCCCACCGC +TGATTCCAGATGCTGCTCTCCTTCTTTCTGGCCAGTCATGATCCTACCTCCCTCCGGGCT +CTGAACCTCACTCCAGCTTCCCTCATCTGCCTGGCGCGTCCTGGCACATTGCCCACCTCC +CTGAGGATGGCGGACCCCGCCCCAATGTGCTCATTCCGCCCGGATTTCCTGAGAAGCGGC +AGGGTCCAGGCTAGACTCTGGGGAGGGGCAGAGGCTCACCAGGGCAGGGAGGAACGCAGA +CATATAAACCGGGAACCCAACAAACAGGGCTCTTGTTCTGGCCAAGGGACACTCGAGGTG +CAAGGGCCTCCACCCCTTGCCTGAGGGCTCTTCCACAGAGGGCATAGAGGAACGAGGGGT +CTCAGGGATGCACCAGAGCGCTGTCCTAATCAGACACGGAGGAGGAGGATGCTATAGGTG +TCAAAACAGGAAGGCGGCCCACAGCAACACTTATGATATAGGATGATCAGGCCAAGGACA +CGTGGTGCTGAACACGGTGGGGTTGGGATTTCGGGGCGGGGAGCACCTGAGTAGCAAGTG +GCTCAGAGAGGTGATCCCTGGGAGGACAGAGAGAACAGACAGGGCAGCCCAGGGAGGGGC +AGGACGCTGAGAGGCTGGCCCACGCAGCCTCTGAGATCATCCCGTGGGGGGCAAGATGGC +TCTCTAGATAGGCTGGCACGCCTGTGGGACGCCGCAGGGACAAGGCTACTCTCTGCAGCA +CTGTCGCAATAGCAAAACCTTAGAAATCATTGCCCTGTGCGTCAACCAGAGGCCAATTAA +ATAAATCCGAAGCTGCATAGCAGAGCACTATGTGGTCCTGAGAACGCAGCTCTTTCTAGA +CCGATAAGAAATGATCTGTGGCCAGGCGCGGTGGCTCACGCCTGTCATCCTAGCACTTTG +GGAGGCGGGGCAGGTGGATCACTTGAGCCCAGGAGTTCAAGGCCAGCCTGGGTAACATGG +CAAAACCCTGTCTCTACAAAAGATACAAAAAATTAACCAGGTGTGGTGGTGCACCTGCAG +TCCCAGCTATTCCGGAGGCTGAGGTAGGAGGATCACCTGAGCCCGGGAAGTCAAGGCTGC +AGCGAGCCATGATCACGCCACTGTACTCCAGGCTGAGTGACAGAGTGAGACCCTGTCTCC +AAAAAAAAAGAAAGATAAAGAAATGATGCCGAAGCTGTACCGTTAAGTGAAAAAAGCACT +GTTTATGTAAACCATATGTATTTGCCTATGCGAGTACAGGAAATCTCACAAAGGAGACAC +AAGAAGCTGACCACAGGGCCGGGCACGGTGGCGCACACCTGTAATCCCAGCAGTTTGGGA +GGCTGAGGCAGGTGGATCACTTGAGGTCAAGAGTTCGAGACTAGCCTGGCCAACATGACA +AAACCCCGTCTCTACTAAAAATACAAAAATTAGCCAGGCATGGTGGGGGGTGCCTGTAAT +CCCAGCTACGTGAGGGGCTGAGGCAGAAAAATCATTTGAATCCCGGAGGCAGAGGTTGCA +GTGAGCCGAGATCACGCCACTGCACTCCATCCTGAGTGACAGAGTGAGACCTTGTCTCAA +AAAAAAAAAAAGAAGCTGACCACAGTGGCTGCCTCTGTGGGGAAAAATTGGAGGCCTGGA +AGATCAGGAAGGAGGGAGGTTTTTTAAAATTATATCCTCCTTTGGAATGTGTGAACGTTT +GCTATTTTTAAAAATTTAAATCAAAATGAGAACATCTGATCCTCTCAAAGAAGAAAGTGA +AATTTTTAAAAGTAATAAACTACCCACGCAGGGAGCACTTTGGGACAAGACTATAAAACG +CCCATGGTGGCTCACGCCTGCCATCCCAGCACTCAGGGAGGCTAAGGCGGGAGGACCACC +TGAGCCCAGGAGTTCAAGGCTGCAGTGAGCTATGGTCACTCCACTGCACTCCAGCCTGTA +TGACAAAGCAAGACCCTGTCTATAAAAAAAATTTTTTTTGTTTGTTTTATTTGAGATGGA +GTCTCGCTCCATTGCCCAGGCTGCCAGTGCAGTGGCACAATTCTCGGCTCATGGCAACCT +CCACCTCCCAGGTTCAAGTGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGAACTACAGG +CACACGCCACCATGCCAGGCTAATTTTTGTATTATCAGTAGAGACAGGGTTTTTTTTTTT +AGACGGAGTCTCGCTCTGTCGTCCAGGCTGGAGTGCAGTGGCGCGATCTCGGCTCACTGC +AAGCTCCACCTCCCGGGTTCAGGCCATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGACT +GCAGGCGCCTGCAACCACACCTGGCTAATTTTTTGCATTTTTAGTAGAGACGGGGTTTCA +CTGTGTTAGCCAGGACGGTCTCCATCTCCTGACCTCGTGATCCGCTCGCCTCAGCCTCCC +AAAGTGCTGGGATTACAGGCATGAGCCACTGCACCCAGCCGAGACAGGGTTTTACCATGT +TGGCCTGGCTGGTCTCGAACTCCTGACCTCATGATCCGCCAGCCTTGGCCTCACAAAGTG +CTGGGATTACAAGCATGAGCCACTGTGAGGGGCCAAAAAATTTTTTAAAAAATGTCCACT +CAGGTCCGCACCCTACTCCCTAGAGCCCCACAAACCCTGTTACCTGTGCCCCCAGGCCAT +ATTGCTTAGTGTAGACAAACATGGCCAGGTCATCAAAGAGTCGCAAGATGGTCCTGCAGT +GGCTGAGTTGGGTGGACACCACCAACAGACGTGTCCCCACTTCGGACCTGGCGGGACACT +GTTCAACCAGAACTCCACCAACCAGCTGGCAGCAGTACCCCAGCACTCGGATCTGTGGGA +AACCAGAAGCAGTCAGTGTGGCCCTCCTGTTCTGCAGAACTGAGCTGCATCCCCCCATAC +CTGGCCCCGGGCCCCGCTGGATTGAGAGTGTGGAAGATTCTCTTTTTTTTTTGAAAGAGT +CTCACTCTGTCATCCAGACTGGAGTGCAGTGGCACGATCTCGGCTCACCGCAGCCTCCAT +CTCCCATGTTCAAGCAATTCTTGTGCCTCAGCCTCCCCAGTAGCTGGGATTACAGGCGCC +CACCACCACACCCTGCTAATTTTTATATTTTTTGTAGAGACAGGGTTTCACCAGGTTGGC +TAGGCTGGTCTCAAACTCATAACCTCAGTGATCCACCTGCCTTAGCCTCCCAAAGTGCTG +GGATTACAGGCATGAGCCACCGTGCCTGACCCAAGAGTTTGGAAGATTCTAAATCTACAA +AGTGACAGTAAAAGCTGAAAGTTTAGGTGGGGCACAGTGGCTCACACCTGTAACCCCAGC +ACTTTGAGAAACCGAGGTGAGAGGATGCCTTCACACCAGGAGTTTGAGACCAGCCTGGGC +AACATAGCAAGACCCTGTGTCTACCAAAAAAATTTTTTTTTTTGAGACGGAGTCTTGCTC +CGTCACCTAGGCTGGAGTGCGGTGGCGCGATCTCGGCTCACTGCAAGCTCCACCTCCCGG +GTTCATGCGATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCACCCGCCACC +AAGCCCACCTAATTTTTTGTATTTTTAGTAGAGATGGGGTTTCACCATTTTAGCCAGGAT +GGTCTTGATCTCCTGACCTCATGATCCACCCGCCTCGGCCTCCCAAAGTGCTGGGATTAC +AGGCGTAAGCCACCGCGCCTGGCTACCAAAAATTTTTTTAAGTTAACAGGGCATGGTGGT +TACTTGGGAGGCTGATGCTGGAGGATCACTTGAGCCCAGGAGTTCCAGACTGTAGTGAGC +TGTAATCGTGCTACTACACTCCAGCCTGGGCAACAGGGCGAGACCCTGTCTAAAAAAAGA +AAAAGAAAAAGAAAAAAAAAGCTGGAAGTTTAAAAACATACTTGGAGGTGGGACAAATGA +AGAAACATGACATCATTGATGTAACTGAAGGGCACAGCCTTTGGGAACAGATGTGACAGG +AACAAAGAAAACAAAGCTCCTTACTTCCCACCTCCTAGGTCCTTCTTTTCCCAGGTGGCA +GGAAGCCACAGCTAAAGTGTATATTTACATCTACCTGCCTGGACCAAAGCCTTTGGATGT +GCTGAATGGTGGGCACAGGTGATCAGGCCTCAACCCAGTGAACAACAGGATAATTTGGTA +GAATTACTTTAGAGAGAAAGAACCTACTCAGTAGGTGATGTGGAGCCTTCTGAAATAGGT +CATCTTCACTACTCAGATCTTTTTTCTTTTGGAGACAGAGTCTTGCTCTGCTCCCCAGGC +TCGAGTGCAAAGGTGTGAGCTCACTGCAACCTCTGCATCCCAGGTTCAAGCAATTCTCCC +GCCTCAGCCTTCCAAGTAGCTGGGACTACAGGCACGCACCACCACATCCGGCTAATTTTT +GTATTTTAGTAGAGACGAGGTTTCATCACTTTTCCCAGGCTGGTCTCAAACTCCTGAGCT +CAGACAATCCACCCAGCTCAGCCTCCCAAAGTGCTAGGATCACAGGCGCGAGCCACCACG +CCTGGCCTCCCTTATATCTTTATTTTACCTGCTTTTCAGAAATTGCTTGTTCCTGTTGTT +TTATTTATTTTTACTTGTAATTCCTTTCCAGCCCCATTATAATGGCAAAACACTGCAATC +TGAATGTTCAACTCGGGGGAGATTTGTTAACCCACCCCCCCAATCATAAGATATTTGAAT +GGAATCTAAATGCCTAGCCACCAGTACACCGCCTGGTACAACCTGAATGTCTACCTATAA +GAGACTGGTGGGGACAAGCTAAGAGTCCAGACTCAGGGGCATGGATGGCATAACCTAAAT +GTTCAACCATATGGGACTTGATTGGAACTAAAAACTGTCCAGCCATAGGGAGAGTCTTGC +AATATCCTAAATCCCCACATGAGATTGTTTGGGACAACCCAGGGACCAACTACAGTGGCC +CGGTCAGATCCTAAATGTCCAAACATGGGAATCTGTTTGGTATGTAAACGTCCAGCCAGG +CTGGGTTGGCAGAGACGATCTAAATGACCAACTGGGGTTTTGTTGGAACCCATCGCTGCT +TAGGCATGGCAGGGCCCAGGCCATGGCGTGTTCTTTGGTCTAGGTTGGCTGAAACAACCT +AAATGCCCAACTATAGGGAATCTGGTTGGAAGTGAATGTCCAGCCACAGGGGAGCCCTGC +AACATCCCAAATCCCAACACGAGATTGTTCAGGACAACTTCAGTGGCCTGGTCGGATCCA +AAACGTCCAAACACGGGAATCTGGCCAGTGTGTCAATGTCCAGACAGGTTGGGTTGGCAG +AAACTATCTAAATGTCCAACGCTGGCCAGACGCGGTGGCTCACGCCTGTAATCCCAGCAC +TTTGGGAGGCCGAGGCAGGTGGATCGCTTGAGGCCAGGAGATCGAGACCATCCTGGCTAA +CACGATGAAACTCCGTCTCTACTAAAAATACAAAAAAATAGCAGGGAGTGGTGGCGGGCG +CCTGTAGTCCCAGCTACTCGGGAGTGCTGAGGCAGGAGAATCGCTTGAACCCGGGAAGCG +GAGGCTGCAGTGAGCAGAGATCGCACCACTGCACTCCAGCCAAAATAAATAAATACATAA +ATGTCCAATGCTAGGGCACCGCATTTGAGCCTAGCTCGGACGGGGCCTCTGCGACGGAGT +ATCCTGGGCGACCCCGTCCCCTCTCTGGCCCGTTTCCCAGTCTCTGAGCTTGGGCCAAAC +TCTAGGACCTCCGGCCCCGGTCCGCCCCTGCCTCACCAGGCGGTCCCGGCCCCTGTACGA +CTCCAGCGCCGACGCCAGGCCGCTCAGCGACGCCATGGCAACTCCGTGACGTCACCGCGA +CGTCGGCGCGCCGCGCCAGGGGGCGGGGCCAGGCCGGGGTACCGGGAGCGCCCCAAAGGC +TTGCGCGCAGGCGCGGCCGCAGGCCTTTGTCCCCCTGACCGGCTTTTTGTCCGCTGTAGG +GGAGGGACAGAGTTTGCAGAGGTGGGGCCGACACGTGTGTGCTCTCCAGGCCTGCAGACC +CTGGATCATCCTCGGAGTTTGCTGCATTCTGCCCCACGGCGGTTTGGCCAACTACCCACG +CACAAAAAAATATATTTCTAAGTTTAACCAACTACCCACACGCTCCAAAAATATTCCAAG +CAAAACCACCAACCTGTTCGCAGTGGTTCAAGGAGAGATTTTCCTTTTTAGTTTTTGTGC +TTCACCTTTTCTGCACTGTCTGCCTGCCCGTAGTGAGCAGGAATGACTGCTGTAATATCA +CAACAAGGCATCTTTCGACGTTAAGGAAAGACGTTATCTTTGGACGTTAAGAATTGTTCT +AGAATACATAAATAAAAAATAAAAATGCACAATTCAGTGACATTAGTACATGCACATGTT +GGACAACCATCACCCCTTGCTAGTTTCGGGGTATTTTTATCACCCCCAAGAGAGACCCCC +GTAGGAGACCAGCATATGCCCCTCTGAAATATGCGACCTTGGTGTAGGATTATTTTGAGC +TGAGATCAATGAAGCTGATACCGGAAAAGCTCTCTGTTCTTCCCTGATTTGCCTCAAAGC +AGGACCTAAAGGTACAAAGGTGCCCTCCTCCCCTCTCTACCAGGAAGGACAAAGGTTGAT +CACCAGGGACACCTTTAGACTCTTGTCTGGAGACGTCTTTTTTTTTTTTTTCTTTTTTTT +TGAGACGGAGTCTTGCTCTGTCCCCAAAGCTAGAGTGCAGTAGCGCCATCTCTGCTCACT +GCGTCCTCCGCTTCCCTGGTTCAAGCGATTCTCGTGCCTCAGCTTCCCAAGTAGCTGGGA +TCACAGCTGTGCACCACTGTGCCCGGCTAATTTTTGTATTTTTGGTAGAGTCGGGGTTTC +ACCACGTTGGCCAGGCTGTTCTCAAATTCCTGGCCTCAAGTGATCCGCCCGCCTCGGCCT +CCCAAAGTGCTGGGATTACAAGCGTGAGCCACCGCACCCGGCCTCAATGTCCTTTTCCTT +CGTCTTGTCACTTCTCCAAAAATTTGCTGCTATATGTTGAAGGTGCTATATAAGCAGGAG +TTATATAAGCTATATAAGCCACCTCATTTCTCTTGGCATCTCCCATGTACACATAAGGTA +CACATGTTAATAAATTTGTTTTTCCCTTGTTAATTTTTTTTTTTTAGACGGAGCCTCGCT +CTGTCGCCCAGGCTGGAGTGCAGTGGCACGATCTCGGCTCACTGCAAGCTCCGCCTCGCG +GGTTCACGCCATTCTTCTGCCTCAGCCTCCCGAGTAGCTGGCACTACTACAGGCGCCCGC +CACCACGCCTGGGTAATTTTTTTTTTTTTTTTTTTTTTGTATTTTTAGTAGAGACGGGGT +TTCACCGTGTTAGCCAGGATGGTCTTGATCTCCTGACCTCGTGATCCGCCCGTCTCTGCC +TCCCAAAGTGCTAGGATTACAGGCGTGAGCCACCGCGCCTGGCCTCTATTTTTTTTTTTT +TTTTTTTTTTTTTTTTTTGAGACAGGGCCTCGCTCTGGGAGGAACCAAATTTGTAGATGT +GAAGCCGCCACTTGTGTGCTCTCTGGGCCTGAGGACCCAGGATGATGCCCAGAGCTTGCT +ACATTCTGCCCCATGGTAGCTTGACCAACTACCCACAAAAAAGGGGTAGAGTGCAGCGGC +ACGATCTTAACTCACTGCAGCCTTGAACTCCTGGGATCAAGCCATCCTGCCACCTCAGCA +TCCTGAGTAGGTGGGACCACAGGTGCCTGCCACCACAATTGGCTAATTTCTTTTTATTTT +TTATTTTTTGTAGAAATGGAGTCTTACCATGTTACCCAGGCTGGCCTTGAGCCCTGGGCT +TAAGCAATCTTCCCACGTCGACCTTCCAAAGTGCTGGAATTACAGGCGTGAACCACCGCA +CCCGCCCTTCTTAATTCTTTCATTGCAAGGATCCATCACAGCTAAGAACTAAGAATAAAG +GAAAAAGTATGTTTCCTCCCCTACACCCTGTTCCCATAAAGCAATCACTCAATTCCTCCC +TCCTCCCAGCCCCTGGCAACCACTAATCTGCATTCTCTGCTGTCTCTCTGTATTTTTACC +ACTTCTTGATTTTTTTTTTTTTTTTTTTTTTTTGAGACAGAGTCTCACTCTGTCACCCAG +ACTGGAGTGCAGTGGCATGATCTCAGCTCACGGCAGCCTCCGCCTCCCAAGTTCAAGCAA +TTCTCCTGCCTCGGCCTCCCAAGTGGCTGAGAGTACAGGTGCGCACCACCACACCCGGCT +AATTTTTGTATTTGTAGTAGAGATGGATTTTACCATGTTGGCCAGGCTGGTCTTGAACTC +TTGACCTCAAGGGATCTGCCTGCCTCGACCTCCCAAAGTGCTGGGATTACAGGCATGAGC +CACCATGCCCGACCTCCTTGATATTTCATACAAATGGAATCATACAATATGTGACCATTT +GTGTCGGCCTCTTCCACCAAGCATAATAGGTTGTTTTGGTTTTTGCTTTTTGTTTTTGAG +ACAGGGTCTTGCTGTGTCACCAGGCTGGAGTGCGGTGGTGTGATCATAGCTCACTGCAGC +CTTGAACTCCTGGGCCTGAGAGATCCTCCTGCCTCAGCCTCCACATTGCCTGGGACTACA +GGTGCACGCCACCACATCTGGCCAATTTTTAAAATTTTTCTTTTGTAGAGATGCGGTCTC +GCTATGTTCACCAGGCTGGTTTCGACCTCCTGGACTCAAGGGATCCTCCTGCCTTGGCCT +CCCAAAGTGCTGGGATTACAGGTGTGAGCCACTGCGTGCAGCTGAGCATAATGGTGTTGA +GGTTTGTCTAAGTTGCAGCATGTATCAGAAATTCATTCCACTTGCAGCTATATAACATTG +CGCCATATGGATGGACCACATTTTGTTTATCCACGTATCAGCTGATGGTCATTTGGGCTG +TTTCTGCCTTTTAGCGATCGTGAATAAGTACAGCTATAAACATTTGTGAATATGTAGTTG +GAGTCCCTGGATTCCATTCCTTTGGGTCTATACCTAGAAGTGGGGTTGCTGGGTCATTTT +GTAACTCTATGTTGAACTTTTTGAGTAATTGCCCAACTGTTTCCCACAGTAGCAGTACCA +TTTTCCATCCCCACCAGCATTACACAAAGGTTCCAATTTCGCCACTTCCTTGCAACATCC +TTTTTTGATTATGATAGCCATCGTAGTAGGTGTGACGTGCCACCCCATTGTGGTTTTGTT +TTGCCTTTTCCTGATGACTAATGATGTCAACGAGTCTGTTTGTTGGTTTGTTTGAATTTT +TTTTTTTGAGACAGAGTGTCACTCTATTGCCTAGGCTGGAGTGCAGTGCTGATCTCAGCT +CACTGCAACCTCCACCTCCCAGGTTCAAGCGATTCTCATGCCTCAGCCTCCCAAATAGCT +GGGATTACAGCACACCCGCCACTGTGCCCGGCTAATTTTAGACTTTTAGTAGAGACGGGG +TTTCGCCATGTTGGCCAGGCTGGTCTCCAACTCCTGATCTCAAGAAATCTGCCCACCTCG +GCCTCCCAAAGTGCTGGGATTATAGGCGTGAGTCACCGCGTCTGGCCTCGATGTTAACCA +GTTTTCTTTCACAGAATATTTCCTCTTGATTTCAACTCTTGTTACTCTTCTCCTGCATTG +CTTTCCTCCTGTTGTTTAAAGTTACAGCAGATTCCTGCCTCAGGAACTTTGCATGTTCTG +TTTCCTCTGCAGAAATGTTCTTGAGCCAGATACCAACGTGGCTCCCTCCTTCCCTAACTT +CCTTTACTCGAATGTCATCCTCTCACGGGACCCACCCGATCACACCCTCCTGGACACTTC +CTACCCATGTTACCTGCTGGTGACCTGTCTTGTTCATGGCTATATCCGCACAGCCTGGCA +GAAAACAGAGAATCTGTTTTGTAAGTTTCACTGCCCTGTCCAAAGATCTCTTCTTGTGCT +CCAAGGGAGCATGGAACACAAGGGGGCACAAGAAAGGCCTTGTCCACTCCTGTGATTTTC +TTCCTCTCTGTCTCTCTCTCTTTCTGTTTTTGTTTTTAAACAGAGTCTCACTCGGTTGCC +CAGGCTGGAGTGCAGTGGCATGATTTCGGCTCACTGCCATCTCCACCTCCCGGGTTCAAG +CAATTCTCCTGCCTCAGCCTCCCAACCAGCTGGGATTACAGGCACCTGCTACCACGCCCC +CACTAATTTTTGGAGTTTTTAATAGAAATAGGGTCTCACCATGTTGGCCAGGCTGGTCTC +AAACTCCTGGGCTCAAGTGATCCACCCACTTCGGCCTCCCAAACTGCTGGGATTACAGGC +ATGGGCCACCATGCCCAGCCTCTTTTTTTTTTCTTCTTGTTTGTTTTTGAGACAGGGTCT +CGCTCTGTTGCCCAGGCTGGAGTGCAGTGGCATGATCATAGCACCACTGCTGCATTGAAC +TCCTGGGTTCAAGTGATCCTCCATCCTCAGCCTCCCATAGCACTGGGATTACAGGTGTGT +GCCACCACACCTGGCCCCAAGAGACTCTTTAACTTCCACATCCAGCTCCTTTTAAGACTT +GGGTCCACTGGCTGAGCTCAGTGACTCACACCTGTAATCCCAATACTTTGGGAGGCCAAG +GCAGGTGGATCACTTGAGGTCAGGAGTTGGAGACCAGCCTGGCCAATATGGTGAAACCCC +GTCTCAAAAAAAAAAAAAAGACTTGGGTCCACGGGTCTTTGTGCACTCCCCTCTCCCCCA +GTGGGGGGGTCACTCTTTTTTTTTTTTTTTAGAGTCAGAGTCTCGCTCTGTCACCCAGGC +TGGAATACAGTGGTATGATCTTAGCTCACTGCAACCTCTGCCTCTGGGTTCAAGTGATTC +TCCTGCCTCAGCCTCCCAAGTAGCTAGGATTACAGGCACCCACCACCACGCCCAGCTAAT +TTTTGTATTTTTAGTAGAGATGGGGTTTTGCCCTGTTGGCCAGGCTGGTCTCGAACTCCT +GACCTTGGGGAATCCTCCCATCTCAGCCTCCTAAAGTGCTGGGATTACAGGCATGAGCCA +CTGCGCCCAGCCACGGGGTCACTGTTTTCACAGCAGAAAAATTGAAGCCAAGCCAGCTGC +AGTGGCCTGTGCCTGTGGTCCCAGCTACTCAGGAGTCTGAGGCACGAGAATCGATTGAAT +CCAGGAGGTGGAGGTTGCAGTGAACCGAGATCACGCCACTGCACTCCAGCCTGGGCGTCA +GCAAGACCCATCTCTAAAAAAGTAAAACAAAAAAAAATCCAAAGCCAAGGTCCAGACATG +CAGAGGAAAGAGGTCACTGGCCGCAAAGCCTGCTGCTGCATGAATAAGCAGATCCCTCCT +CTCAGGCCCAAGAGCCTTGGAACAGCGCAATGCATTTGCCCGAATGCTTCCTGTGTGCCG +GGTCCCGCTCTAGGCAACAGAGATACAGCAGTGAGCTTTGCAGACACAGCCCAGCCCTCC +CAGCGTCCCCCATCTGGCTAGGTCTGAGCTCGACCTTTGAAAAAGACACAGGAGCTGGCC +TGGTGTTCACAGCTGGCCTTGGTGTTGCTAGGAGCTGGCCTGGCAGTCAAAGCAGGGCCC +TGGTGTCCTCCTGCTGGACATAAACAATCTCACATGACGCCGACATCAGACAAGGCCACT +CTGTGACCGCGGCAGAGCAAGACAAAACAAGCCTGCTCCATAATCATGTCTGAACACAGG +CAAAACACGAACACTGTCCACACTATCAGAGTAACTGGACCTCCTCTGCTACTAGCTAAT +ACCAGCAACGGCTGTTCCTTACCAAGCACAGCTTTAGTCTTCTGACTTCTTTCTTTCTTT +CTTTCCTTCCTTCCTTCCCTCCTTCCCCTCCCTCCCTCCTTCCTTCCTTCTTCCTTCCTT +TCCCTCCCTCCCTGCTTCCTTCCCTCCTTCTCTCCCTCCCTCCTTCCCTCCTTCTTTCCT +TCTTCCTTCCTTTCCCTCCCTTCCTCCCTCCTTCCTTCCCTTCGTCCTTCCTTCCTTCCT +TCCAGCTCCCAGCTTCCCTGGAGCTCTAAGGAGGCAGGATTTGCACAAAAAACAAAACCG +TGCCCCCAAAACACCTAACAGAACTGCAGATCCCAAATCCCTCCCTCCCTCCCTCCCTCG +CTCCCTCCCTTCCTTCCTTCCCTCCCTCTCTCCTTCCTTCCTTCTGACTTCTTCATACAG +ATGATTAAGATGCTGAATAATAGTTACTTCTCTCCCTAGCTGCTCTTTTGTTTTGTGTTG +TTTCTGAGACAGAGTCTCACTCTGTCACCCAGGCTGGAGTGCAGTGGCGGAATCATAGCT +CACTGCACCCTCACTGCAACCTCAATGTCCTGGGTTCAAGAAATCTTCCCACCTTAGCCT +CCCAAGTAGCTGGGACTATAGGCACGCGCCACCGCACCTGGCTTTTTAATTTTTTATAGA +GATAGGGTCTCACTGTGTTGCCCAGGCTGGTCTCAAACACCTGGGCTCAAGCAGTCCTCC +CGCTTCAGCCTCTCAAAGTGATGGGATTACAGGCCTGAGGCACTGCACTCAGCCGCCCTT +GCTTCTTTTTTTTTTTTTGAGACAGAGTTTTGCTCTGTGGCCCAAGCTGGAGTGCAGTGG +CACGATCTCAGTTCACTGCAACCTCCACCACCTGGGTTCAAGCGATTCTCCTGCCTCAGC +CTCCTGAGTAGCTGGGATTACAGGTGCCCGCCACCATGCCCAGCTAGTTTTTTTTTTCTT +TGAGACAGAGTTTTGCTCTTGTCTCCCAGGCTGGAGTGCAATGGCGTGATCTCAGCTCAC +TGCAACCTCCGCCTCCTGGGTTCACGCAATTCTCCTGCCTCAGGCTCCTGAGTAGCTGGG +AATACAGGTGCCCGCCACCACACCCGGCTATTTTTTATATTTTTAGTAGAGACAGGGTTT +CACCATGTTGGCCAGGCTGGCCTCGAACTCCTGACCAAAGGAGATCCGCCTGCCTCAGCC +TCCTGAGTAGCGGGGATTACAGGCGTGAGCCACCACGCCCGGCTAATTTTTGTATTTTCA +GTAGAGACAGGGTTTCACCGTGTTCGCCAGGCTGGTCTCAAACTCCTGACCTCAAGTGAT +CCACCCACCTTGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCACACCAAGCCA +CAACAGCCCTTTTCTGGACGCTACTTTGGGAGGCTGAGATTACAAATGTGAGCCACCATG +CCTCACCTGTGTGTTGTTTTTATTTGTTTTTATCTGCTCATCTCAAAAAAGAAAGTAAAA +TTTCCAACCAATAAATTCATCCCACCCAAATCCCCTACTTCCTTAAGCTGTGCCCCCAAA +ACACCGAGCAGAATTGCAAATCCCATAATAAGTGCTTTCTGGCCGGGCGTGGTGGCTCAC +GCCTATAATCCCAGCACTTCGGGAGACTGAAGCGAGCGGATCACCCGAGGTCGGCAATTC +GAAACCAGCCTGACCAACATGGAAAAACCCCATCTCTACTAAAAATACAAAATTAGCTGG +GTGTGGTGGCACATGCCTATAATCCCAGCTACTCGGGAGCCTGAGGCAGGAGAATCACTT +GAAGCCGGAGGTTGCGATGAGCTGAGATCGTGCCACTGCACCCCAGCCTGGGCAACAAGA +GCGAAACTCCATCTCAAATAAATAAATAAATAAATAAATAGCGAAAAAAAGTTCTTTCTA +ACACCTCCCTACTGAGACCGCCATAGTGCCCTATGACATGTATGAGCTCTCTCTCCCTCT +CTCTTTCTTTCTCTCTCTCTCTCTGATGAATAATAAGCTTGAATGTGTTCAATCACAGGT +ACATTCCTGGTGGTCTTTGACTGGGGAAGGAGGGGTGACCGGCCCCTTTAAAGGGAGATC +TGTGAGCCCTAGAATAATATCAAGAGGTGCAGTGATTCAGGGAAGTGGGTCCATTCTGTG +TGGGGTGTGTAGAAGGTAGAGGGACAGAAAAACTTTAGAGGATGATAATAATAATGGACA +CCAGCAGCCTATTTAATCAAATCCTCAATACTGACACTGCTTTCTGAACTGGCTACCATC +ATTAGTCCCCTTTTGCAGATGACAAAACCTAAGTCCTAGCCAGGCATGGTGGCACACACC +TGTGGACCCACCCACTTGGGAGGCTGAGGCGAGAGGATCGCTTGAGCCCAGGACTTCAAG +TCCAGCCTGGGCAACATAGCGAGAGCTTACCTCAAAAACAAAACCAACCGAACAAAACCC +CAGAGGCTCCAAAAAGTCAATTACTTGCCTGGGTTCCTGGAGCTCTAAGGAGGCAGTATT +CGCACCAAGCCTGCCTGCTAATTTTCCTCCCGGCT diff --git a/test/csq/ENST00000593942/ENST00000593942.fa.fai b/test/csq/ENST00000593942/ENST00000593942.fa.fai new file mode 100644 index 0000000..e3e22d7 --- /dev/null +++ b/test/csq/ENST00000593942/ENST00000593942.fa.fai @@ -0,0 +1 @@ +19 20615 23 60 61 diff --git a/test/csq/ENST00000593942/ENST00000593942.gff b/test/csq/ENST00000593942/ENST00000593942.gff new file mode 100644 index 0000000..6f339b5 --- /dev/null +++ b/test/csq/ENST00000593942/ENST00000593942.gff @@ -0,0 +1,18 @@ +19 ensembl_havana gene 21 20595 . - . ID=gene:ENSG00000104883;Name=PEX11G;biotype=protein_coding;description=peroxisomal biogenesis factor 11 gamma [Source:HGNC Symbol%3BAcc:20208];gene_id=ENSG00000104883;logic_name=ensembl_havana_gene;version=3 +19 ensembl_havana transcript 22 20595 . - . ID=transcript:ENST00000593942;Parent=gene:ENSG00000104883;Name=PEX11G-002;biotype=protein_coding;havana_transcript=OTTHUMT00000458966;havana_version=1;tag=basic;transcript_id=ENST00000593942;version=1 +19 havana three_prime_UTR 22 347 . - . Parent=transcript:ENST00000593942 +19 havana exon 22 582 . - . Parent=transcript:ENST00000593942;Name=ENSE00003214970;constitutive=0;ensembl_end_phase=-1;ensembl_phase=2;exon_id=ENSE00003214970;rank=7;version=1 +19 havana CDS 348 582 . - 1 ID=CDS:ENSP00000472216;Parent=transcript:ENST00000593942;protein_id=ENSP00000472216 +19 havana exon 1460 1522 . - . Parent=transcript:ENST00000593942;Name=ENSE00003562909;constitutive=0;ensembl_end_phase=2;ensembl_phase=2;exon_id=ENSE00003562909;rank=6;version=1 +19 havana CDS 1460 1522 . - 1 ID=CDS:ENSP00000472216;Parent=transcript:ENST00000593942;protein_id=ENSP00000472216 +19 havana exon 5179 5357 . - . Parent=transcript:ENST00000593942;Name=ENSE00003600419;constitutive=0;ensembl_end_phase=2;ensembl_phase=0;exon_id=ENSE00003600419;rank=5;version=1 +19 havana CDS 5179 5357 . - 0 ID=CDS:ENSP00000472216;Parent=transcript:ENST00000593942;protein_id=ENSP00000472216 +19 havana CDS 8984 9022 . - 0 ID=CDS:ENSP00000472216;Parent=transcript:ENST00000593942;protein_id=ENSP00000472216 +19 havana exon 8984 9172 . - . Parent=transcript:ENST00000593942;Name=ENSE00003621789;constitutive=0;ensembl_end_phase=0;ensembl_phase=-1;exon_id=ENSE00003621789;rank=4;version=1 +19 havana five_prime_UTR 9023 9172 . - . Parent=transcript:ENST00000593942 +19 havana exon 12494 12658 . - . Parent=transcript:ENST00000593942;Name=ENSE00003020804;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003020804;rank=3;version=1 +19 havana five_prime_UTR 12494 12658 . - . Parent=transcript:ENST00000593942 +19 havana exon 14128 14268 . - . Parent=transcript:ENST00000593942;Name=ENSE00003109739;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003109739;rank=2;version=1 +19 havana five_prime_UTR 14128 14268 . - . Parent=transcript:ENST00000593942 +19 havana exon 20549 20595 . - . Parent=transcript:ENST00000593942;Name=ENSE00003217935;constitutive=0;ensembl_end_phase=-1;ensembl_phase=-1;exon_id=ENSE00003217935;rank=1;version=1 +19 havana five_prime_UTR 20549 20595 . - . Parent=transcript:ENST00000593942 diff --git a/test/csq/ENST00000593942/last-codon-deletion.txt b/test/csq/ENST00000593942/last-codon-deletion.txt new file mode 100644 index 0000000..6672fc4 --- /dev/null +++ b/test/csq/ENST00000593942/last-codon-deletion.txt @@ -0,0 +1,3 @@ +349 CA C stop_lost&frameshift|PEX11G|ENST00000593942|protein_coding|-|172*>172D|349CA>C +349 CA C stop_lost&frameshift|PEX11G|ENST00000593942|protein_coding|-|172*>172D|349CA>C + diff --git a/test/csq/ENST00000593942/last-codon-deletion.vcf b/test/csq/ENST00000593942/last-codon-deletion.vcf new file mode 100644 index 0000000..8616ed2 --- /dev/null +++ b/test/csq/ENST00000593942/last-codon-deletion.vcf @@ -0,0 +1,7 @@ +##fileformat=VCFv4.2 +##contig= +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO +19 349 . CA C . . EXP=stop_lost&frameshift|PEX11G|ENST00000593942|protein_coding|-|172*>172D|349CA>C;type=ENST00000593942:7542089-CA-C, deletion in the last codon, tr.ref needs context diff --git a/test/csq/ENST00000624631/ENST00000624631.fa b/test/csq/ENST00000624631/ENST00000624631.fa new file mode 100644 index 0000000..85aa8ce --- /dev/null +++ b/test/csq/ENST00000624631/ENST00000624631.fa @@ -0,0 +1,25 @@ +>7 7:65140428-65141823 +TACAAAGCATCATAAAGTATGATTTGCAGACATATTTTATAAATTGGAACACCTTAAGGA +TTCATGGCATTTGTGTAAAATGTGTGGTCGTTAACACATTTTAATACATTGATTCTATTG +TGGAAGGTCGTGTGACATGGAATGTTAAACAATTAAAATGGTCAAATGTACTTCCATGTT +TATGTGATTTGCATTCACAGGAAGAAAATGGGTAATGCCGAAGGAACATTGGCCTAGAGA +AGCTTACTGAAGCAAGGGAATTTGGAGTGAGACTTTCTCCCGCTGCGGCTTTCTGCCCCC +ACACCGCGGCTTTTGCAGCTTTTTGCCTCCGCTGCCGCGGCGTTTTGGTCCCCGCCGCCG +CGGCTTTTTGTGGTTTTTTTGCCCCAGCTCCCACTGCTTTTTGTCCCCCCCGCCGCGGCT +TTTTGCCCCCGCCCCGGCGGCTTTCTTCCGCCGCGGCTTTTTGCCCCGCCGCCGCGCATT +TTTGCCGCCGCGGCTTTTTGCCCCCGCCGCCTAAGCTTTTTGCCTGCGCCGCCGCGGCTT +TTTGCCCCCCGTCGCCGCGGCTTTTTGCCGCCGCGGCTTTCTGCTCCCGCCGCCACGGCT +CTGAGGGCGGGAGCGGCAGACTCCGCTGCCAGCTCTACTGGCGTCCTGGCAAGGGCAGCG +CCGAGGGGCGCTCCCGGTCCAGCTCTCCCGGCTCGGGGGTTCCTTGCCTAGGCGCCAGAG +CCCCGGGCTCCCTGCCTCGGCCGCTGTGGCCTGCATAGAGCGGCACTGCGCGCGGAGGCG +ATGGGAGAGAAGAAGGAGGGCGGTGGCGGGGGTGATGCAGCGGCCGCTGAGGGTGGCGCA +GGGGCCCCGGCCAGCCCGGGGCTGCAGCAGTGCAGACAGCTCCAGAAGCTCATCGGCATC +TCCATTGGCAGCCTGCGCGGGCTGGGCACCAAGTGCGCTGTGTCCAACGACCTCACCGAG +CAGGAGATACGGACCCTGGAGGTAAGGGGTTTGGGGACCCGGGCTGGGCTCGAGGAGCGG +CCCGGACACCTCCCTTGAGGCCCCAGTTCACTCCTGGCCGAGTTGCATCCTTGAGCCCGC +GTCGCGCCCTTGGAGGCTTCCCCTCCCTCCTGCACTCGCTGATGGGGCAGCCGAGAGACC +CGGGACCAGCCCTCACCTTGGGCAGGATTTGTGGGGCGAGTGCTTGGTGGGAACTGGGAT +GGAGGCTCTAGGGTCCCGTGGGGCGGGGAGGGTGGGGGTGGGCTGCGCGCGGACATCCCC +TTACCCCCGAATTTCCATCTGGTCCGGCCCTCTCATCTTGTAGGTGAGGAAACCAAAGGC +CTGAGGGAGAACTGACTTGCCAGGAACCCCTGTTAAGGAGAATTACCAAAGTGTGGTTAT +TAAAGGAGAACTGAGT diff --git a/test/csq/ENST00000624631/ENST00000624631.fa.fai b/test/csq/ENST00000624631/ENST00000624631.fa.fai new file mode 100644 index 0000000..274aedd --- /dev/null +++ b/test/csq/ENST00000624631/ENST00000624631.fa.fai @@ -0,0 +1 @@ +7 1396 23 60 61 diff --git a/test/csq/ENST00000624631/ENST00000624631.gff b/test/csq/ENST00000624631/ENST00000624631.gff new file mode 100644 index 0000000..b6005b4 --- /dev/null +++ b/test/csq/ENST00000624631/ENST00000624631.gff @@ -0,0 +1,8 @@ +7 ensembl gene 101 1296 . - . ID=gene:ENSG00000280410;Name=AC104073.1;biotype=protein_coding;gene_id=ENSG00000280410;logic_name=ensembl;version=1 +7 ensembl mRNA 101 1296 . - . ID=transcript:ENST00000624631;Parent=gene:ENSG00000280410;Name=AC104073.1-201;biotype=protein_coding;tag=basic;transcript_id=ENST00000624631;transcript_support_level=5;version=1 +7 ensembl exon 101 544 . - . Parent=transcript:ENST00000624631;Name=ENSE00003758654;constitutive=1;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003758654;rank=3;version=1 +7 ensembl CDS 101 544 . - 0 ID=CDS:ENSP00000485644;Parent=transcript:ENST00000624631;protein_id=ENSP00000485644 +7 ensembl exon 547 975 . - . Parent=transcript:ENST00000624631;Name=ENSE00003759678;constitutive=1;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003759678;rank=2;version=1 +7 ensembl CDS 547 975 . - 0 ID=CDS:ENSP00000485644;Parent=transcript:ENST00000624631;protein_id=ENSP00000485644 +7 ensembl exon 1264 1296 . - . Parent=transcript:ENST00000624631;Name=ENSE00003757286;constitutive=1;ensembl_end_phase=0;ensembl_phase=0;exon_id=ENSE00003757286;rank=1;version=1 +7 ensembl CDS 1264 1296 . - 0 ID=CDS:ENSP00000485644;Parent=transcript:ENST00000624631;protein_id=ENSP00000485644 diff --git a/test/csq/ENST00000624631/ambiguous.txt b/test/csq/ENST00000624631/ambiguous.txt new file mode 100644 index 0000000..2ee26bf --- /dev/null +++ b/test/csq/ENST00000624631/ambiguous.txt @@ -0,0 +1,3 @@ +547 CCC CC frameshift|AC104073.1|ENST00000624631|protein_coding|-|154GQKAAAAQAKSLGGGGKKPRRQKCAAAGQKAAAEESRRGGGKKPRRGGQKAVGAGAKKPQKAAAAGTKTPRQRRQKAAKAAVWGQKAAAGESLTPNSLASVSFSRPMFLRHYPFSSCECKSHKHGSTFDHFNCLTFHVTRPSTIESMY*>154GKKPRRRRQKA*|547CCC>CC,splice_region|AC104073.1|ENST00000624631|protein_coding +547 CCC CC frameshift|AC104073.1|ENST00000624631|protein_coding|-|154GQKAAAAQAKSLGGGGKKPRRQKCAAAGQKAAAEESRRGGGKKPRRGGQKAVGAGAKKPQKAAAAGTKTPRQRRQKAAKAAVWGQKAAAGESLTPNSLASVSFSRPMFLRHYPFSSCECKSHKHGSTFDHFNCLTFHVTRPSTIESMY*>154GKKPRRRRQKA*|547CCC>CC,splice_region|AC104073.1|ENST00000624631|protein_coding + diff --git a/test/csq/ENST00000624631/ambiguous.vcf b/test/csq/ENST00000624631/ambiguous.vcf new file mode 100644 index 0000000..bf8b1aa --- /dev/null +++ b/test/csq/ENST00000624631/ambiguous.vcf @@ -0,0 +1,7 @@ +##fileformat=VCFv4.2 +##contig= +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO +7 547 . CCC CC . . type=ENST00000624631:65140974-CCC-CC;EXP=splice_region|AC104073.1|ENST00000624631|protein_coding,frameshift|AC104073.1|ENST00000624631|protein_coding|-|154GQKAAAAQAKSLGGGGKKPRRQKCAAAGQKAAAEESRRGGGKKPRRGGQKAVGAGAKKPQKAAAAGTKTPRQRRQKAAKAAVWGQKAAAGESLTPNSLASVSFSRPMFLRHYPFSSCECKSHKHGSTFDHFNCLTFHVTRPSTIESMY*>154GKKPRRRRQKA*|547CCC>CC diff --git a/test/csq/ENST00000624631/ascii-art.txt b/test/csq/ENST00000624631/ascii-art.txt new file mode 100644 index 0000000..2d58095 --- /dev/null +++ b/test/csq/ENST00000624631/ascii-art.txt @@ -0,0 +1,11 @@ + + + 547 + iiieeeeeeeeee... +TTTTGCCCCCCGTCGCCGCGG +TTTTGCCC-CCGTCGC + + iiieeeeeeeeee... +TTTTG-CCCCCGTCGC +TTTTGCCCCC-GTCGC + diff --git a/test/csq/ENST00000624631/segfault.txt.new b/test/csq/ENST00000624631/segfault.txt.new new file mode 100644 index 0000000..4375db6 --- /dev/null +++ b/test/csq/ENST00000624631/segfault.txt.new @@ -0,0 +1,3 @@ +547 CCC CC . +547 CCC CC frameshift|AC104073.1|ENST00000624631|protein_coding|-|154GQKAAAAQAKSLGGGGKKPRRQKCAAAGQKAAAEESRRGGGKKPRRGGQKAVGAGAKKPQKAAAAGTKTPRQRRQKAAKAAVWGQKAAAGESLTPNSLASVSFSRPMFLRHYPFSSCECKSHKHGSTFDHFNCLTFHVTRPSTIESMY*>154GKKPRRRRQKA*|547CCC>CC,splice_region|AC104073.1|ENST00000624631|protein_coding + diff --git a/test/csq/make-csq-test b/test/csq/make-csq-test new file mode 100755 index 0000000..48c8ae4 --- /dev/null +++ b/test/csq/make-csq-test @@ -0,0 +1,276 @@ +#!/usr/bin/env perl +# +# Author: petr.danecek@sanger +# + +use strict; +use warnings; +use Carp; +use FindBin; +$ENV{PATH} = $FindBin::RealBin."/../../:$ENV{PATH}"; + +my $opts = parse_params(); +parse_gff($opts); +create_ref($opts); +create_vcf($opts,0); +create_vcf($opts,$$opts{offset}); +create_gff($opts,0); +create_gff($opts,$$opts{offset}); +run_vep($opts); +run_bcsq($opts,$$opts{offset}); +run_bcsq($opts,0); + +exit; + +#-------------------------------- + +sub error +{ + my (@msg) = @_; + if ( scalar @msg ) { confess @msg; } + print + "Usage: make-csq-test [OPTIONS]\n", + "Options:\n", + " -f, --fasta-ref \n", + " -g, --gff \n", + " -i, --indels introduce indels\n", + " -o, --output \n", + " -p, --position \n", + " --pad [20]\n", + " -t, --transcript \n", + " -h, -?, --help This help message.\n", + "\n", + "Example:\n", + " ./make-csq-test -f \$ref -g \$gff -o rmme -p 3566625-AGCAGGCTG-A -t ENST00000378322\n", + "\n"; + exit -1; +} +sub parse_params +{ + my $opts = { indels=>0, pad=>20 }; + while (defined(my $arg=shift(@ARGV))) + { + if ( $arg eq '--pad' ) { $$opts{pad}=shift(@ARGV); next; } + if ( $arg eq '-p' || $arg eq '--position' ) { $$opts{pos}=shift(@ARGV); next; } + if ( $arg eq '-i' || $arg eq '--indels' ) { $$opts{indels}=shift(@ARGV); next; } + if ( $arg eq '-f' || $arg eq '--fasta-ref' ) { $$opts{ref}=shift(@ARGV); next; } + if ( $arg eq '-t' || $arg eq '--transcript' ) { $$opts{tscript}=shift(@ARGV); next; } + if ( $arg eq '-g' || $arg eq '--gff' ) { $$opts{gff}=shift(@ARGV); next; } + if ( $arg eq '-o' || $arg eq '--output' ) { $$opts{out}=shift(@ARGV); next; } + if ( $arg eq '-?' || $arg eq '-h' || $arg eq '--help' ) { error(); } + error("Unknown parameter \"$arg\". Run -h for help.\n"); + } + if ( !exists($$opts{ref}) ) { error("Missing the -f option.\n") } + if ( !exists($$opts{gff}) ) { error("Missing the -g option.\n") } + if ( !exists($$opts{out}) ) { error("Missing the -o option.\n") } + if ( !exists($$opts{tscript}) ) { error("Missing the -t option.\n") } + return $opts; +} +sub parse_gff +{ + my ($opts) = @_; + my @buf = (); + open(my $fh,"gunzip -c $$opts{gff} |") or error("gunzip -c $$opts{gff}: $!"); + while (my $line=<$fh>) + { + if ( $line=~/^###/ ) { @buf = (); next; } + if ( $line=~/^#/ ) { next; } + my @vals = split(/\t/,$line); + push @buf,\@vals; + if ( $vals[8]=~/ID=transcript:$$opts{tscript};/ ) { last; } + } + if ( !@buf ) { error("Transcript $$opts{tscript} not found in $$opts{gff}\n"); } + if ( !($buf[-1][8]=~/Parent=gene:([^;\s+]+)/) ) { error("Gene ID not present: $buf[-1][8]\n"); } + my $gene_id = $1; + while (my $line=<$fh>) + { + if ( $line=~/^###/ ) { last; } + my @vals = split(/\t/,$line); + push @buf,\@vals; + } + my $tline; + my @dat = (); + for my $line (@buf) + { + if ( $$line[8]=~/ID=gene:$gene_id/ ) { push @dat,$line; next; } + if ( $$line[8]=~/ID=transcript:$$opts{tscript}/ ) { push @dat,$line; $tline = $line; next; } + if ( $$line[8]=~/Parent=transcript:$$opts{tscript}/ ) { push @dat,$line; next; } + } + close($fh); + $$opts{dat} = \@dat; + $$opts{offset} = $$tline[3] - $$opts{pad} - 1; +} +sub get_chr_beg_end +{ + my ($rec) = @_; + return ($$rec[0],$$rec[3],$$rec[4]); +} +sub get_type +{ + my ($rec) = @_; + if ( $$rec[2] eq 'gene' ) { return $$rec[2]; } + if ( $$rec[2] eq 'transcript' ) { return $$rec[2]; } + if ( $$rec[2] eq 'exon' ) { return $$rec[2]; } + if ( $$rec[2] eq 'CDS' ) { return $$rec[2]; } + if ( $$rec[2] eq 'three_prime_UTR' ) { return $$rec[2]; } + if ( $$rec[2] eq 'five_prime_UTR' ) { return $$rec[2]; } + error("Unknown type: $$rec[2] .. ".join("\t",@$rec)); +} +sub get_strand +{ + my ($rec) = @_; + return $$rec[6]; +} +sub create_ref +{ + my ($opts) = @_; + my ($chr,$beg,$end) = get_chr_beg_end($$opts{dat}[0]); + $beg -= $$opts{pad}; + $end += $$opts{pad}; + my $ref = ''; + open(my $out,'>',"$$opts{out}.fa") or error("$$opts{out}.fa: $!"); + open(my $fh,"samtools faidx $$opts{ref} $chr:$beg-$end|") or error("samtools faidx $$opts{ref} $chr:$beg-$end: $!"); + <$fh>; + print $out ">$chr\t$chr:$beg-$end\n"; + while (my $line=<$fh>) + { + print $out $line; + chomp($line); + $ref .= $line; + } + close($fh); + close($out); + $$opts{refseq} = $ref; + `rm -f $$opts{out}.fai; samtools faidx $$opts{out}.fa`; +} +sub create_vcf +{ + my ($opts,$offset) = @_; + my $strand = get_strand($$opts{dat}[0]); + my ($chr,$beg0,$end0) = get_chr_beg_end($$opts{dat}[0]); + my %dat; + if ( exists($$opts{pos}) ) + { + my ($pos,$ref,$alt) = split(/-/,$$opts{pos}); + $dat{$pos}{ref} = $ref; + $dat{$pos}{alt} = $alt; + push @{$dat{$pos}{type}}, "$$opts{tscript}:$$opts{pos}"; + } + else + { + for my $dat (@{$$opts{dat}}) + { + my ($chr,$beg,$end) = get_chr_beg_end($dat); + my $type = get_type($dat); + for my $off (-9,-8,-4,-3,-2,0,2,3,4,8,9) + { + my $pos = $beg + $off; + if ( $pos<$beg0 or $pos>$end0 ) { next; } + if ( $$opts{indels} == 0 ) + { + $dat{$pos}{ref} = substr($$opts{refseq},$pos-$beg0,1); + $dat{$pos}{alt} = $dat{$pos}{ref} eq 'A' ? 'C' : 'A'; + } + elsif ( $$opts{indels} > 0 ) + { + $dat{$pos}{ref} = substr($$opts{refseq},$pos-$beg0,1); + $dat{$pos}{alt} = $dat{$pos}{ref}. ('A' x $$opts{indels}); + } + else + { + if ( $pos-$beg0-$$opts{indels} > length($$opts{refseq}) ) { next; } + $dat{$pos}{ref} = substr($$opts{refseq},$pos-$beg0,-$$opts{indels}); + $dat{$pos}{alt} = substr($$opts{refseq},$pos-$beg0,1); + } + push @{$dat{$pos}{type}}, "$type:$off"; + } + } + } + my $fname = $offset ? "$$opts{out}.vcf" : "$$opts{out}.vcf.ori"; + open(my $out,'>',"$fname") or error("$fname: $!"); + print $out qq[##fileformat=VCFv4.2\n]; + print $out qq[##contig=\n]; + print $out qq[##INFO=\n]; + print $out qq[##INFO=\n]; + print $out qq[##INFO=\n]; + print $out "#".join("\t", qw(CHROM POS ID REF ALT QUAL FILTER INFO))."\n"; + for my $pos (sort {$a<=>$b} keys %dat) + { + my $ref = $dat{$pos}{ref}; + my $alt = $dat{$pos}{alt}; + my $type = join(',',@{$dat{$pos}{type}}); + print $out join("\t",($chr,$pos-$offset,'.',$ref,$alt,'.','.',"type=$type"))."\n"; + } + close($out); +} +sub create_gff +{ + my ($opts,$offset) = @_; + my $fname = $offset ? "$$opts{out}.gff" : "$$opts{out}.gff.ori"; + open(my $out,'>',"$fname") or error("$fname: $!"); + for my $dat (@{$$opts{dat}}) + { + my (@x) = (@$dat); + $x[3] -= $offset; + $x[4] -= $offset; + print $out join("\t",@x); + } + close($out); +} +sub run_vep +{ + my ($opts) = @_; + + my $vep = "perl -I /software/vertres/installs/ensembl/82/ /software/vertres/bin-external/variant_effect_predictor_v82.pl --db_version 82 -t SO --format vcf --force_overwrite --cache --dir /lustre/scratch116/vr/ref/ensembl/vep_cache/ --species human --offline --symbol --biotype --vcf --no_stats --assembly GRCh37 --no_progress --quiet -o -"; + my $cmd = "cat $$opts{out}.vcf.ori | $vep | bcftools query -f'%POS\\t%REF\\t%ALT\\t%CSQ\\n'"; + + open(my $fh,"$cmd |") or error("$cmd: $!"); + open(my $out,'>',"$$opts{out}.vep.txt") or error("$$opts{out}.vep.txt: $!"); + while (my $line=<$fh>) + { + my @out = (); + my ($pos,$ref,$alt,$csq) = split(/\t/,$line); + my @csq = split(/,/,$csq); + chomp($csq[-1]); + for my $csq (@csq) + { + if ( $csq=~/Transcript\|$$opts{tscript}/ ) { push @out,$csq; } + } + if ( !scalar @out ) { @out = ('.'); } + $csq = join(',',@out); + print $out join("\t",($pos,$ref,$alt,$csq))."\n"; + } + close($fh); + close($out); +} +sub run_bcsq +{ + my ($opts,$offset) = @_; + my $fname = $offset ? "$$opts{out}.bcsq.txt" : "$$opts{out}.bcsq.txt.ori"; + my $vcf = $offset ? "$$opts{out}.vcf" : "$$opts{out}.vcf.ori"; + my $gff = $offset ? "$$opts{out}.gff" : $$opts{gff}; + my $ref = $offset ? "$$opts{out}.fa" : $$opts{ref}; + + my $cmd = "bcftools csq -f $ref -g $gff $vcf | bcftools query -f'%POS\\t%REF\\t%ALT\\t%BCSQ\\n'"; + + print STDERR "$cmd\n"; + open(my $fh,"$cmd |") or error("$cmd: $!"); + open(my $out,'>',$fname) or error("$fname: $!"); + while (my $line=<$fh>) + { + my @out = (); + my ($pos,$ref,$alt,$csq) = split(/\t/,$line); + my @csq = split(/,/,$csq); + chomp($csq[-1]); + for my $csq (@csq) + { + if ( !($csq=~/Transcript/) or $csq=~/Transcript\|$$opts{tscript}/ ) { push @out,$csq; } + } + if ( !scalar @out ) { @out = ('.'); } + $csq = join(',',@out); + print $out join("\t",($pos,$ref,$alt,$csq))."\n"; + } + close($fh); + close($out); +} + diff --git a/test/csq/sort-csq b/test/csq/sort-csq new file mode 100755 index 0000000..85b64c7 --- /dev/null +++ b/test/csq/sort-csq @@ -0,0 +1,62 @@ +#!/usr/bin/env perl +# +# Author: petr.danecek@sanger +# + +use strict; +use warnings; +use Carp; + +my $opts = parse_params(); +sort_csq($opts); + +exit; + +#-------------------------------- + +sub error +{ + my (@msg) = @_; + if ( scalar @msg ) { confess @msg; } + print + "Usage: sort-csq [OPTIONS]\n", + "Options:\n", + " -h, -?, --help This help message.\n", + "\n"; + exit -1; +} +sub parse_params +{ + my $opts = {}; + while (defined(my $arg=shift(@ARGV))) + { + if ( $arg eq '-?' || $arg eq '-h' || $arg eq '--help' ) { error(); } + error("Unknown parameter \"$arg\". Run -h for help.\n"); + } + return $opts; +} + +sub sort_csq +{ + my ($opts) = @_; + while (my $line=) + { + if ( $line=~/^#/ ) { print $line; next; } + chomp($line); + $line = sort_csq_tag($line,'EXP'); + $line = sort_csq_tag($line,'BCSQ'); + print $line."\n"; + } +} + +sub sort_csq_tag +{ + my ($line,$tag) = @_; + if ( !($line=~/$tag=([^;\t]+)/) ) { return $line; } + my $beg = $`; + my $end = $'; + my $hit = $1; + my @vals = sort split(/,/,$hit); + return $beg."$tag=".join(',',@vals).$end; +} + diff --git a/test/dosage.out b/test/dosage.out new file mode 100644 index 0000000..e3cab1d --- /dev/null +++ b/test/dosage.out @@ -0,0 +1,15 @@ +#[1]CHROM [2]POS [3]REF [4]ALT [5]A [6]B +1 3000150 C T -1.0 -1.0 +1 3000151 C T -1.0 -1.0 +1 3062915 GTTT G 1.0 1.0 +1 3062915 G T 1.0 1.0 +1 3106154 CAAA C -1.0 -1.0 +1 3106154 C CT -1.0 -1.0 +1 3157410 GA G 2.0 2.0 +1 3162006 GAA G -1.0 -1.0 +1 3177144 G T -1.0 -1.0 +1 3177144 G . 0.0 0.0 +1 3184885 TAAAA TA -1.0 -1.0 +2 3199812 G GTT -1.0 -1.0 +3 3212016 CTT C -1.0 -1.0 +4 3258448 TACACACAC T -1.0 -1.0 diff --git a/test/empty.idx.out b/test/empty.idx.out new file mode 100644 index 0000000..e69de29 diff --git a/test/empty.idx_count.out b/test/empty.idx_count.out new file mode 100644 index 0000000..573541a --- /dev/null +++ b/test/empty.idx_count.out @@ -0,0 +1 @@ +0 diff --git a/test/empty.vcf b/test/empty.vcf new file mode 100644 index 0000000..def4e42 --- /dev/null +++ b/test/empty.vcf @@ -0,0 +1,6 @@ +##fileformat=VCFv4.1 +##contig= +##contig= +##contig= +##contig= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA00001 NA00002 NA00003 diff --git a/test/ex1.gtf.gz b/test/ex1.gtf.gz new file mode 100644 index 0000000000000000000000000000000000000000..693db0c6372a12d4299eb20a49cfb54ebba94882 GIT binary patch literal 3778 zcmV;z4n6T7iwFb&00000{{{d;LjnMM3+f&>0tNYFDc2fB#RU&N}fbM1uCNn!_<#oo)7Yny#4wJi??T=-hTY$ z!{YPR^je?EG8yjiVpAMd|EZ5mt^ z4Y-huYTKar*{A<~UmhKQe|&ga-mk82AMWl~UpC)cKixe2SRWn#=j{B?v&|P*H{a|J zTwVa2Fn$5-4K#n3r^8x{cDJ=}?RI`biTeeAE&pErb;N!?`g-&C&Fbdb{a22T&#$iD zfBsm$Z~Mnc+w@I2hUoW#zR)`*oMyWtgq{eUE4iRTBJ_!&*Q3=6y5<-? 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NS=3;DP=14;AF=0.5;HOMSEQ;DB GT:GQ:DP:HQ:CNL 0|0:48:1:25,30:10,20 1|0:48:8:49,51:. ./.:43:5:.,.:1 +20 17330 . T A . q10;s50 NS=3;DP=11;AF=0.017;H2 GT:GQ:DP:HQ 0|0:49:3:58,50 0|1:3:5:65,3 0/0:41:3:4,5 +20 1110696 rs6040355 A G,T 67 PASS NS=2;DP=10;AF=0.333,0.667;AA=T;DB GT:GQ:DP:HQ 1|2:21:6:23,27 2|1:2:0:18,2 2/2:35:4:10,20 +20 1230237 . T . 47 PASS NS=3;DP=13;AA=T GT:GQ:DP:HQ 0|0:54:7:56,60 0|0:48:4:51,51 ./. +20 1234567 microsat1 GTC G,GTCT 50 PASS NS=3;DP=9;AA=G GT:GQ:DP 0/1:35:4 0/2:17:2 1/1:40:3 diff --git a/test/ex3.sam b/test/ex3.sam new file mode 100644 index 0000000..974aa80 --- /dev/null +++ b/test/ex3.sam @@ -0,0 +1,14 @@ +@SQ SN:ref LN:45 +@SQ SN:ref2 LN:40 +r001 163 ref 7 30 8M4I4M1D3M = 37 39 TTAGATAAAGAGGATACTG * XX:B:S,12561,2,20,112 YY:i:100 +r002 0 ref 9 30 1S2I6M1P1I1P1I4M2I * 0 0 AAAAGATAAGGGATAAA * XA:Z:abc XB:i:-10 +r003 0 ref 9 30 5H6M * 0 0 AGCTAA * +r004 0 ref 16 30 6M14N1I5M * 0 0 ATAGCTCTCAGC * +r003 16 ref 29 30 6H5M * 0 0 TAGGC * +r001 83 ref 37 30 9M = 7 -39 CAGCGCCAT * +x1 0 ref2 1 30 20M * 0 0 aggttttataaaacaaataa * +x2 0 ref2 2 30 21M * 0 0 ggttttataaaacaaataatt ????????????????????? +x3 0 ref2 6 30 9M4I13M * 0 0 ttataaaacAAATaattaagtctaca ?????????????????????????? +x4 0 ref2 10 30 25M * 0 0 CaaaTaattaagtctacagagcaac ????????????????????????? +x5 0 ref2 12 30 24M * 0 0 aaTaattaagtctacagagcaact ???????????????????????? +x6 0 ref2 14 30 23M * 0 0 Taattaagtctacagagcaacta ??????????????????????? diff --git a/test/fill-AN-AC.out b/test/fill-AN-AC.out new file mode 100644 index 0000000..82fc827 --- /dev/null +++ b/test/fill-AN-AC.out @@ -0,0 +1,38 @@ +##fileformat=VCFv4.1 +##FILTER= +##INFO= +##FORMAT= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FILTER= +##FILTER= +##contig= +##contig= +##contig= +##contig= +##test= +##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta +##readme=AAAAAA +##readme=BBBBBB +##INFO= +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B +1 3000150 . C T 59.2 PASS AN=0;AC=0 GT:GQ ./.:245 ./.:245 +1 3000151 . C T 59.2 PASS AN=0;AC=0 GT:DP:GQ ./.:32:245 ./.:32:245 +1 3062915 id3D GTTT G 12.9 q10 DP4=1,2,3,4;INDEL;STR=test;AN=4;AC=2 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 0/1:409:35:-20,-5,-20 +1 3062915 idSNP G T,C 12.6 test TEST=5;DP4=1,2,3,4;AN=3;AC=1,1 GT:TT:GQ:DP:GL 0/1:0,1:409:35:-20,-5,-20,-20,-5,-20 2:0,1:409:35:-20,-5,-20 +1 3106154 . CAAA C 342 PASS AN=0;AC=0 GT:GQ:DP ./.:245:32 ./.:245:32 +1 3106154 . C CT 59.2 PASS AN=0;AC=0 GT:GQ:DP ./.:245:32 ./.:245:32 +1 3157410 . GA G 90.6 q10 AN=4;AC=4 GT:GQ:DP 1/1:21:21 1/1:21:21 +1 3162006 . GAA G 60.2 PASS AN=0;AC=0 GT:GQ:DP ./.:212:22 ./.:212:22 +1 3177144 . G T 45 PASS AN=0;AC=0 GT:GQ:DP ./.:150:30 ./.:150:30 +1 3177144 . G . 45 PASS AN=0 GT:GQ:DP ./.:150:30 ./.:150:30 +1 3184885 . TAAAA TA,T 61.5 PASS AN=0;AC=0,0 GT:GQ:DP ./.:12:10 ./.:12:10 +2 3199812 . G GTT,GT 82.7 PASS AN=0;AC=0,0 GT:GQ:DP ./.:322:26 ./.:322:26 +3 3212016 . CTT C,CT 79 PASS AN=0;AC=0,0 GT:GQ:DP ./.:91:26 ./.:91:26 +4 3258448 . TACACACAC T 59.9 PASS AN=0;AC=0 GT:GQ:DP ./.:325:31 ./.:325:31 diff --git a/test/fill-tags-hemi.1.out b/test/fill-tags-hemi.1.out new file mode 100644 index 0000000..44d4f3c --- /dev/null +++ b/test/fill-tags-hemi.1.out @@ -0,0 +1,19 @@ +##fileformat=VCFv4.2 +##FILTER= +##FORMAT= +##contig= +##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B +1 3177144 . G T,A 45 PASS NS=2;AN=2;AF=0.5,0.5;MAF=0.5,0.5;AC=1,1;AC_Het=0,0;AC_Hom=0,0;AC_Hemi=1,1;HWE=1,1 GT 1 2 +1 3177144 . G T 45 PASS NS=2;AN=2;AF=0.5;MAF=0.5;AC=1;AC_Het=0;AC_Hom=0;AC_Hemi=1;HWE=1 GT 0/. 1/. +1 3177144 . G T 45 PASS NS=2;AN=2;AF=0.5;MAF=0.5;AC=1;AC_Het=0;AC_Hom=0;AC_Hemi=1;HWE=1 GT ./0 ./1 +1 3177144 . G T 45 PASS NS=1;AN=1;AF=1;MAF=0;AC=1;AC_Het=0;AC_Hom=0;AC_Hemi=1;HWE=1 GT ./. ./1 diff --git a/test/fill-tags-hemi.2.out b/test/fill-tags-hemi.2.out new file mode 100644 index 0000000..0079d1f --- /dev/null +++ b/test/fill-tags-hemi.2.out @@ -0,0 +1,19 @@ +##fileformat=VCFv4.2 +##FILTER= +##FORMAT= +##contig= +##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B +1 3177144 . G T,A 45 PASS NS=2;AN=2;AF=0.5,0.5;MAF=0.5,0.5;AC=1,1;AC_Het=0,0;AC_Hom=0,0;AC_Hemi=1,1;HWE=1,1 GT 1 2 +1 3177144 . G T 45 PASS NS=2;AN=2;AF=0.5;MAF=0.5;AC=1;AC_Het=0;AC_Hom=0;AC_Hemi=0;HWE=1 GT 0/. 1/. +1 3177144 . G T 45 PASS NS=2;AN=2;AF=0.5;MAF=0.5;AC=1;AC_Het=0;AC_Hom=0;AC_Hemi=0;HWE=1 GT ./0 ./1 +1 3177144 . G T 45 PASS NS=1;AN=1;AF=1;MAF=0;AC=1;AC_Het=0;AC_Hom=0;AC_Hemi=0;HWE=1 GT ./. ./1 diff --git a/test/fill-tags-hemi.vcf b/test/fill-tags-hemi.vcf new file mode 100644 index 0000000..4d52282 --- /dev/null +++ b/test/fill-tags-hemi.vcf @@ -0,0 +1,9 @@ +##fileformat=VCFv4.2 +##FORMAT= +##contig= +##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B +1 3177144 . G T,A 45 PASS . GT 1 2 +1 3177144 . G T 45 PASS . GT 0/. 1/. +1 3177144 . G T 45 PASS . GT ./0 ./1 +1 3177144 . G T 45 PASS . GT ./. ./1 diff --git a/test/fill-tags.2.out b/test/fill-tags.2.out new file mode 100644 index 0000000..2c06a7a --- /dev/null +++ b/test/fill-tags.2.out @@ -0,0 +1,50 @@ +##fileformat=VCFv4.1 +##FILTER= +##reference=file:///seq/references/1000Genomes-NCBI37.fasta +##contig= +##contig= +##contig= +##contig= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FILTER= +##FILTER= +##FILTER= +##FILTER= +##FILTER= +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA00001 NA00002 NA00003 +11 2343543 . A . 999 PASS DP=100223;NS=3;AN=6 GT:PL:DP:GQ 0/0:0,255,255:193:99 0/0:0,255,255:211:99 0/0:0,255,255:182:99 +11 5464562 . C T 999 PASS DP=0;NS=0;AN=0;AC=0 GT:PL:DP:GQ ./.:0,0,0:.:. ./.:0,0,0:.:. ./.:0,0,0:.:. +20 76962 rs6111385 T C 999 PASS DP4=110138,70822,421911,262673;DP=911531;Dels=0;FS=21.447;HWE=0.491006;ICF=-0.01062;MQ0=1;MQ=46;PV4=2.5e-09,0,0,1;QD=22.31;NS=3;AN=6;AF=0.833333;MAF=0.166667;AC=5 GT:PL:DP:GQ 0/1:255,0,255:193:99 1/1:255,255,0:211:99 1/1:255,255,0:182:99 +20 126310 . ACC A 999 StrandBias;EndDistBias DP4=125718,95950,113812,80890;DP=461867;HWE=0.24036;ICF=0.01738;INDEL;IS=374,0.937343;MQ=49;PV4=9e-30,1,0,3.8e-13;QD=0.0172;AN=6;AC=4;NS=3;AF=0.666667;MAF=0.333333 GT:DP:GQ:PL 0/1:117:99:255,0,132 0/1:111:99:255,0,139 1/1:78:99:255,213,0 +20 138125 rs2298108 G T 999 PASS DP4=174391,20849,82080,4950;DP=286107;Dels=0;FS=3200;HWE=0.199462;ICF=0.01858;MQ0=0;MQ=46;PV4=0,0,0,1;QD=17.22;AN=6;AC=4;NS=3;AF=0.666667;MAF=0.333333 GT:PL:DP:GQ 0/1:135,0,163:66:99 0/1:140,0,255:71:99 1/1:255,199,0:66:99 +20 138148 rs2298109 C T 999 PASS DP4=194136,45753,94945,14367;DP=356657;Dels=0;FS=3200;HWE=0.177865;ICF=0.0198;MQ0=0;MQ=47;PV4=0,0,0,1;QD=14.57;AN=6;AC=4;NS=3;AF=0.666667;MAF=0.333333 GT:PL:DP:GQ 0/1:195,0,255:87:99 0/1:192,0,255:82:99 1/1:255,235,0:78:99 +20 271225 . T TTTA,TA 999 StrandBias DP4=29281,42401,27887,29245;DP=272732;INDEL;IS=95,0.748031;MQ=47;PV4=0,1,0,1;QD=0.0948;AN=6;AC=2,2;NS=3;AF=0.333333,0.333333;MAF=0.333333,0.333333 GT:DP:GQ:PL 0/2:33:49:151,53,203,0,52,159 0/1:51:99:255,0,213,255,255,255 1/2:47:99:255,255,255,255,0,241 +20 304568 . C T 999 PASS DP4=16413,4543,945,156;DP=43557;Dels=0;FS=3200;HWE=0.076855;ICF=0.0213;MQ0=0;MQ=50;PV4=0,0,0,1;QD=15.45;AN=6;AC=4;NS=3;AF=0.666667;MAF=0.333333 GT:PL:DP:GQ 0|1:95,0,255:90:99 0|1:192,0,255:13:99 1|1:255,95,0:60:99 +20 326891 . A AC 999 PASS DP4=125718,95950,113812,80890;DP=461867;HWE=0.24036;ICF=0.01738;INDEL;IS=374,0.937343;MQ=49;PV4=9e-30,1,0,3.8e-13;QD=0.0172;AN=4;AC=2;NS=2;AF=0.5;MAF=0.5 GT:DP:GQ:PL 0|1:117:99:255,0,132 0|1:111:99:255,0,139 ./.:.:.:.,.,. +X 2928329 rs62584840 C T 999 PASS DP4=302,9137,32,1329;DP=11020;Dels=0;FS=13.38;HWE=0.284332;ICF=0.0253;MQ0=0;MQ=49;PV4=0.094,0,0,1;QD=18.61;AN=4;AC=1;NS=3;AF=0.25;MAF=0.25 GT:PL:DP:GQ 0:0,56:2:73 0:0,81:3:98 0/1:73,0,19:4:30 +X 2933066 rs61746890 G C 999 PASS DP4=69865,100561,461,783;DP=173729;Dels=0;FS=10.833;MQ0=0;MQ=50;PV4=0.005,3.6e-14,0,1;QD=15.33;AN=4;AC=1;NS=3;AF=0.25;MAF=0.25 GT:PL:DP:GQ 0:0,255:39:99 0:0,255:37:99 0/1:255,255,255:62:99 +X 2942109 rs5939407 T C 999 PASS DP4=23273,27816,40128,48208;DP=146673;Dels=0;FS=43.639;HWE=0.622715;ICF=-0.01176;MQ0=1;MQ=46;PV4=0.65,1,0,1;QD=14.81;AN=4;AC=3;NS=3;AF=0.75;MAF=0.25 GT:PL:DP:GQ 0:0,255:20:99 1:255,0:33:99 1/1:255,157,0:52:99 +X 3048719 . T C 999 PASS DP4=13263,27466,40128,48208;DP=146673;Dels=0;FS=43.639;HWE=0.622715;ICF=-0.01176;MQ0=1;MQ=46;PV4=0.65,1,0,1;QD=14.81;AN=4;AC=2;NS=3;AF=0.5;MAF=0.5 GT:PL:DP:GQ 0:0,255:20:99 1:255,0:33:99 0|1:255,0,157:52:99 +Y 8657215 . C A 999 PASS DP4=74915,114274,1948,2955;DP=195469;Dels=0;FS=3.181;MQ0=0;MQ=50;PV4=0.86,1,0,1;QD=33.77;AN=2;AC=1;NS=2;AF=0.5;MAF=0.5 GT:PL:DP:GQ 0:0,255:47:99 1:255,0:64:99 .:.:.:. +Y 10011673 rs78249411 G A 999 MinAB DP4=47351,30839,178796,279653;DP=550762;Dels=0;FS=41.028;MQ0=37362;MQ=26;PV4=0,0,0,1;QD=17.45;AN=2;AC=2;NS=2;AF=1;MAF=0 GT:PL:DP:GQ 1:126,101:146:37 1:95,0:130:99 .:.:.:. diff --git a/test/fill-tags.3.out b/test/fill-tags.3.out new file mode 100644 index 0000000..9ee18d3 --- /dev/null +++ b/test/fill-tags.3.out @@ -0,0 +1,49 @@ +##fileformat=VCFv4.1 +##FILTER= +##reference=file:///seq/references/1000Genomes-NCBI37.fasta +##contig= +##contig= +##contig= +##contig= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FILTER= +##FILTER= +##FILTER= +##FILTER= +##FILTER= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA00001 NA00002 NA00003 +11 2343543 . A . 999 PASS DP=100223 GT:PL:DP:GQ 0/0:0,255,255:193:99 0/0:0,255,255:211:99 0/0:0,255,255:182:99 +11 5464562 . C T 999 PASS DP=0;AC_AB=0;AC_BC=0;AC=0 GT:PL:DP:GQ ./.:0,0,0:.:. ./.:0,0,0:.:. ./.:0,0,0:.:. +20 76962 rs6111385 T C 999 PASS DP4=110138,70822,421911,262673;DP=911531;Dels=0;FS=21.447;HWE=0.491006;ICF=-0.01062;MQ0=1;MQ=46;PV4=2.5e-09,0,0,1;QD=22.31;AC_AB=3;AC_BC=4;AC=5 GT:PL:DP:GQ 0/1:255,0,255:193:99 1/1:255,255,0:211:99 1/1:255,255,0:182:99 +20 126310 . ACC A 999 StrandBias;EndDistBias DP4=125718,95950,113812,80890;DP=461867;HWE=0.24036;ICF=0.01738;INDEL;IS=374,0.937343;MQ=49;PV4=9e-30,1,0,3.8e-13;QD=0.0172;AN=6;AC=4;AC_AB=2;AC_BC=3 GT:DP:GQ:PL 0/1:117:99:255,0,132 0/1:111:99:255,0,139 1/1:78:99:255,213,0 +20 138125 rs2298108 G T 999 PASS DP4=174391,20849,82080,4950;DP=286107;Dels=0;FS=3200;HWE=0.199462;ICF=0.01858;MQ0=0;MQ=46;PV4=0,0,0,1;QD=17.22;AN=6;AC=4;AC_AB=2;AC_BC=3 GT:PL:DP:GQ 0/1:135,0,163:66:99 0/1:140,0,255:71:99 1/1:255,199,0:66:99 +20 138148 rs2298109 C T 999 PASS DP4=194136,45753,94945,14367;DP=356657;Dels=0;FS=3200;HWE=0.177865;ICF=0.0198;MQ0=0;MQ=47;PV4=0,0,0,1;QD=14.57;AN=6;AC=4;AC_AB=2;AC_BC=3 GT:PL:DP:GQ 0/1:195,0,255:87:99 0/1:192,0,255:82:99 1/1:255,235,0:78:99 +20 271225 . T TTTA,TA 999 StrandBias DP4=29281,42401,27887,29245;DP=272732;INDEL;IS=95,0.748031;MQ=47;PV4=0,1,0,1;QD=0.0948;AN=6;AC=2,2;AC_AB=1,1;AC_BC=2,1 GT:DP:GQ:PL 0/2:33:49:151,53,203,0,52,159 0/1:51:99:255,0,213,255,255,255 1/2:47:99:255,255,255,255,0,241 +20 304568 . C T 999 PASS DP4=16413,4543,945,156;DP=43557;Dels=0;FS=3200;HWE=0.076855;ICF=0.0213;MQ0=0;MQ=50;PV4=0,0,0,1;QD=15.45;AN=6;AC=4;AC_AB=2;AC_BC=3 GT:PL:DP:GQ 0|1:95,0,255:90:99 0|1:192,0,255:13:99 1|1:255,95,0:60:99 +20 326891 . A AC 999 PASS DP4=125718,95950,113812,80890;DP=461867;HWE=0.24036;ICF=0.01738;INDEL;IS=374,0.937343;MQ=49;PV4=9e-30,1,0,3.8e-13;QD=0.0172;AN=4;AC=2;AC_AB=2;AC_BC=1 GT:DP:GQ:PL 0|1:117:99:255,0,132 0|1:111:99:255,0,139 ./.:.:.:.,.,. +X 2928329 rs62584840 C T 999 PASS DP4=302,9137,32,1329;DP=11020;Dels=0;FS=13.38;HWE=0.284332;ICF=0.0253;MQ0=0;MQ=49;PV4=0.094,0,0,1;QD=18.61;AN=4;AC=1;AC_AB=0;AC_BC=1 GT:PL:DP:GQ 0:0,56:2:73 0:0,81:3:98 0/1:73,0,19:4:30 +X 2933066 rs61746890 G C 999 PASS DP4=69865,100561,461,783;DP=173729;Dels=0;FS=10.833;MQ0=0;MQ=50;PV4=0.005,3.6e-14,0,1;QD=15.33;AN=4;AC=1;AC_AB=0;AC_BC=1 GT:PL:DP:GQ 0:0,255:39:99 0:0,255:37:99 0/1:255,255,255:62:99 +X 2942109 rs5939407 T C 999 PASS DP4=23273,27816,40128,48208;DP=146673;Dels=0;FS=43.639;HWE=0.622715;ICF=-0.01176;MQ0=1;MQ=46;PV4=0.65,1,0,1;QD=14.81;AN=4;AC=3;AC_AB=1;AC_BC=3 GT:PL:DP:GQ 0:0,255:20:99 1:255,0:33:99 1/1:255,157,0:52:99 +X 3048719 . T C 999 PASS DP4=13263,27466,40128,48208;DP=146673;Dels=0;FS=43.639;HWE=0.622715;ICF=-0.01176;MQ0=1;MQ=46;PV4=0.65,1,0,1;QD=14.81;AN=4;AC=2;AC_AB=1;AC_BC=2 GT:PL:DP:GQ 0:0,255:20:99 1:255,0:33:99 0|1:255,0,157:52:99 +Y 8657215 . C A 999 PASS DP4=74915,114274,1948,2955;DP=195469;Dels=0;FS=3.181;MQ0=0;MQ=50;PV4=0.86,1,0,1;QD=33.77;AN=2;AC=1;AC_AB=1;AC_BC=1 GT:PL:DP:GQ 0:0,255:47:99 1:255,0:64:99 .:.:.:. +Y 10011673 rs78249411 G A 999 MinAB DP4=47351,30839,178796,279653;DP=550762;Dels=0;FS=41.028;MQ0=37362;MQ=26;PV4=0,0,0,1;QD=17.45;AN=2;AC=2;AC_AB=2;AC_BC=1 GT:PL:DP:GQ 1:126,101:146:37 1:95,0:130:99 .:.:.:. diff --git a/test/fill-tags.3.smpl b/test/fill-tags.3.smpl new file mode 100644 index 0000000..4ac8f7d --- /dev/null +++ b/test/fill-tags.3.smpl @@ -0,0 +1,3 @@ +NA00001 AB +NA00002 AB,BC +NA00003 BC diff --git a/test/fill-tags.out b/test/fill-tags.out new file mode 100644 index 0000000..eb8676f --- /dev/null +++ b/test/fill-tags.out @@ -0,0 +1,40 @@ +##fileformat=VCFv4.1 +##FILTER= +##INFO= +##FORMAT= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FILTER= +##FILTER= +##contig= +##contig= +##contig= +##contig= +##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta +##readme=AAAAAA +##readme=BBBBBB +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B +1 3000150 . C T 59.2 PASS AN=4;AC=2;AC_Het=2;AC_Hom=0;AC_Hemi=0 GT:GQ 0/1:245 0/1:245 +1 3000151 . C T 59.2 PASS AN=4;AC=2;AC_Het=2;AC_Hom=0;AC_Hemi=0 GT:DP:GQ 0/1:32:245 0/1:32:245 +1 3062915 id3D GTTT G 12.9 q10 DP4=1,2,3,4;AN=4;AC=2;INDEL;STR=test;AC_Het=2;AC_Hom=0;AC_Hemi=0 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 0/1:409:35:-20,-5,-20 +1 3062915 idSNP G T,C 12.6 test TEST=5;DP4=1,2,3,4;AN=3;AC=1,1;AC_Het=1,0;AC_Hom=0,0;AC_Hemi=0,1 GT:TT:GQ:DP:GL 0/1:0,1:409:35:-20,-5,-20,-20,-5,-20 2:0,1:409:35:-20,-5,-20 +1 3106154 . CAAA C 342 PASS AN=4;AC=2;AC_Het=2;AC_Hom=0;AC_Hemi=0 GT:GQ:DP 0/1:245:32 0/1:245:32 +1 3106154 . C CT 59.2 PASS AN=4;AC=2;AC_Het=2;AC_Hom=0;AC_Hemi=0 GT:GQ:DP 0/1:245:32 0/1:245:32 +1 3157410 . GA G 90.6 q10 AN=4;AC=4;AC_Het=0;AC_Hom=4;AC_Hemi=0 GT:GQ:DP 1/1:21:21 1/1:21:21 +1 3162006 . GAA G 60.2 PASS AN=4;AC=2;AC_Het=2;AC_Hom=0;AC_Hemi=0 GT:GQ:DP 0/1:212:22 0/1:212:22 +1 3177144 . G T 45 PASS AN=4;AC=2;AC_Het=0;AC_Hom=2;AC_Hemi=0 GT:GQ:DP 0/0:150:30 1/1:150:30 +1 3177144 . G . 45 PASS AN=4 GT:GQ:DP 0/0:150:30 0/0:150:30 +1 3184885 . TAAAA TA,T 61.5 PASS AN=4;AC=2,2;AC_Het=2,2;AC_Hom=0,0;AC_Hemi=0,0 GT:GQ:DP 1/2:12:10 1/2:12:10 +2 3199812 . G GTT,GT 82.7 PASS AN=4;AC=2,2;AC_Het=2,2;AC_Hom=0,0;AC_Hemi=0,0 GT:GQ:DP 1/2:322:26 1/2:322:26 +3 3212016 . CTT C,CT 79 PASS AN=4;AC=2,2;AC_Het=2,2;AC_Hom=0,0;AC_Hemi=0,0 GT:GQ:DP 1/2:91:26 1/2:91:26 +4 3258448 . TACACACAC T . PASS AN=4;AC=2;AC_Het=2;AC_Hom=0;AC_Hemi=0 GT:GQ:DP 0/1:325:31 0/1:325:31 diff --git a/test/filter-missing-floats.vcf b/test/filter-missing-floats.vcf new file mode 100644 index 0000000..8ecd43b --- /dev/null +++ b/test/filter-missing-floats.vcf @@ -0,0 +1,42 @@ +##fileformat=VCFv4.2 +##contig= +##FORMAT= +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO +1 201 . A T 0 PASS A_AF=0.00008;B_AF=0.00008;C_AF=0.00008 +1 202 . A T 0 PASS A_AF=0.00008 +1 203 . A T 0 PASS A_AF=0.00008;B_AF=0.00008; +1 204 . A T 0 PASS A_AF=0.00008;C_AF=0.00008 +1 205 . A T 0 PASS B_AF=0.00008 +1 206 . A T 0 PASS B_AF=0.00008;C_AF=0.00008 +1 207 . A T 0 PASS C_AF=0.00008 +1 301 . A T 0 PASS A_AF=0.00008;B_AF=0.00008;C_AF=0.00012 +1 302 . A T 0 PASS A_AF=0.00008; +1 303 . A T 0 PASS A_AF=0.00008;B_AF=0.00008; +1 304 . A T 0 PASS A_AF=0.00008;C_AF=0.00012 +1 305 . A T 0 PASS B_AF=0.00008 +1 306 . A T 0 PASS B_AF=0.00008;C_AF=0.00012 +1 307 . A T 0 PASS C_AF=0.00012 +1 401 . A T 0 PASS A_AF=0.00008;B_AF=0.00012;C_AF=0.00008 +1 402 . A T 0 PASS A_AF=0.00008; +1 403 . A T 0 PASS A_AF=0.00008;B_AF=0.00012 +1 404 . A T 0 PASS A_AF=0.00008;C_AF=0.00008 +1 405 . A T 0 PASS B_AF=0.00012 +1 406 . A T 0 PASS B_AF=0.00012;C_AF=0.00008 +1 407 . A T 0 PASS C_AF=0.00008 +1 501 . A T 0 PASS A_AF=0.00012;B_AF=0.00008;C_AF=0.00008 +1 502 . A T 0 PASS A_AF=0.00012; +1 503 . A T 0 PASS A_AF=0.00012;B_AF=0.00008 +1 504 . A T 0 PASS A_AF=0.00012;C_AF=0.00008 +1 505 . A T 0 PASS B_AF=0.00008 +1 506 . A T 0 PASS B_AF=0.00008;C_AF=0.00008 +1 507 . A T 0 PASS C_AF=0.00008 +1 1001 . A T 0 PASS A_AF=0.00012;B_AF=0.00012;C_AF=0.00012 +1 1002 . A T 0 PASS A_AF=0.00012; +1 1003 . A T 0 PASS A_AF=0.00012;B_AF=0.00012 +1 1004 . A T 0 PASS A_AF=0.00012;C_AF=0.00012 +1 1005 . A T 0 PASS B_AF=0.00012 +1 1006 . A T 0 PASS B_AF=0.00012;C_AF=0.00012 +1 1007 . A T 0 PASS C_AF=0.00012 diff --git a/test/filter.1.out b/test/filter.1.out new file mode 100644 index 0000000..bc2218a --- /dev/null +++ b/test/filter.1.out @@ -0,0 +1,30 @@ +##fileformat=VCFv4.1 +##FILTER= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FILTER= +##test= +##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta +##contig= +##contig= +##INFO= +##INFO= +##readme=AAAAAA +##readme=BBBBBB +##FILTER= +##FILTER= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A +1 1000 . G A 1806 PASS DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 +1 1003 . GT G 1806 PASS DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 +1 1007 . G A 1806 PASS DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 +1 2000 . T C 1806 PASS DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 +1 2003 . T TC 1806 PASS DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 +1 2006 . T C 1806 PASS DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 +2 1001 . GT G 1806 PASS DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 +2 1008 . GT G 1806 PASS DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 +2 2001 . A AT 1806 PASS DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 +2 2006 . A AT 1806 PASS DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 diff --git a/test/filter.1.vcf b/test/filter.1.vcf new file mode 100644 index 0000000..de41bc6 --- /dev/null +++ b/test/filter.1.vcf @@ -0,0 +1,33 @@ +##fileformat=VCFv4.1 +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FILTER= +##test= +##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta +##contig= +##contig= +##INFO= +##INFO= +##readme=AAAAAA +##readme=BBBBBB +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A +1 1000 . G A 1806 . DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 +1 1001 . G A 1806 . DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 +1 1003 . GT G 1806 . DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 +1 1006 . G A 1806 . DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 +1 1007 . G A 1806 . DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 +1 2000 . T C 1806 . DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 +1 2001 . T C 1806 . DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 +1 2003 . T TC 1806 . DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 +1 2005 . T C 1806 . DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 +1 2006 . T C 1806 . DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 +2 1001 . GT G 1806 . DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 +2 1004 . GT G 1806 . DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 +2 1008 . GT G 1806 . DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 +2 2001 . A AT 1806 . DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 +2 2003 . A AT 1806 . DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 +2 2006 . A AT 1806 . DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 diff --git a/test/filter.10.out b/test/filter.10.out new file mode 100644 index 0000000..0574390 --- /dev/null +++ b/test/filter.10.out @@ -0,0 +1,11 @@ +##fileformat=VCFv4.1 +##FILTER= +##contig= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT sample1 sample2 +chr1 1 . A T 100 PASS TEST1=10;TEST2=10 GT:TEST3:TEST4 0/1:10:10 ./.:30:30 +chr1 2 . A T 100 PASS TEST1=50;TEST2=50 GT:TEST3:TEST4 0/1:20:20 ./.:40:40 diff --git a/test/filter.11.out b/test/filter.11.out new file mode 100644 index 0000000..8b58d63 --- /dev/null +++ b/test/filter.11.out @@ -0,0 +1,26 @@ +##fileformat=VCFv4.1 +##FILTER= +##INFO= +##FORMAT= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FILTER= +##FILTER= +##contig= +##contig= +##contig= +##contig= +##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta +##readme=AAAAAA +##readme=BBBBBB +##INFO= +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B +1 3106154 . CAAA C 342 PASS AN=4;AC=2 GT:GQ:DP 0/1:245:32 0/1:25:300 +1 3106154 . C CT 59.2 PASS AN=4;AC=2 GT:GQ:DP 0/1:25:12 0/1:245:310 +1 3157410 . GA G 90.6 q10 AN=4;AC=4 GT:GQ:DP 1/1:21:21 1/1:21:21 diff --git a/test/filter.2.out b/test/filter.2.out new file mode 100644 index 0000000..0a53bf3 --- /dev/null +++ b/test/filter.2.out @@ -0,0 +1,38 @@ +##fileformat=VCFv4.1 +##FILTER= +##INFO= +##FORMAT= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FILTER= +##FILTER= +##contig= +##contig= +##contig= +##contig= +##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta +##readme=AAAAAA +##readme=BBBBBB +##INFO= +##INFO= +##INFO= +##INFO= +##FILTER= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B +1 3000150 . C T 59.2 Modified AN=0;AC=0 GT:GQ ./.:245 ./.:245 +1 3000151 . C T 59.2 Modified AN=0;AC=0 GT:DP:GQ ./.:32:245 ./.:32:245 +1 3062915 id3D GTTT G 12.9 q10 DP4=1,2,3,4;AN=4;AC=2;INDEL;STR=test GT:GQ:DP:GL 0/1:25:35:-20,-5,-20 0/1:45:11:-20,-5,-20 +1 3062915 idSNP G T,C 12.6 test TEST=5;DP4=1,2,3,4;AN=3;AC=1,1 GT:TT:GQ:DP:GL 0/1:0,1:409:35:-20,-5,-20,-20,-5,-20 2:0,1:409:35:-20,-5,-20 +1 3106154 . CAAA C 342 Modified AN=2;AC=1 GT:GQ:DP 0/1:245:32 ./.:25:300 +1 3106154 . C CT 59.2 Modified AN=0;AC=0 GT:GQ:DP ./.:25:12 ./.:245:310 +1 3157410 . GA G 90.6 q10 AN=4;AC=4 GT:GQ:DP 1/1:21:21 1/1:21:21 +1 3162006 . GAA G 60.2 PASS AN=4;AC=2 GT:GQ:DP 0/1:212:22 0/1:212:22 +1 3177144 . G T 45 PASS AN=4;AC=2 GT:GQ:DP 0/0:150:30 1/1:150:30 +1 3177144 . G . 45 PASS AN=4;AC=0 GT:GQ:DP 0/0:150:30 0/0:150:30 +1 3184885 . TAAAA TA,T 61.5 Modified AN=2;AC=1,1 GT:GQ:DP ./.:12:10 1/2:12:20 +2 3199812 . G GTT,GT 82.7 Modified AN=2;AC=1,1 GT:GQ:DP 1/2:322:20 ./.:322:10 +3 3212016 . CTT C,CT 79 PASS AN=4;AC=2,2 GT:GQ:DP 1/2:91:26 1/2:91:26 +4 3258448 . TACACACAC T 59.9 PASS AN=4;AC=2 GT 0/1 0/1 diff --git a/test/filter.2.vcf b/test/filter.2.vcf new file mode 100644 index 0000000..b86a64b --- /dev/null +++ b/test/filter.2.vcf @@ -0,0 +1,36 @@ +##fileformat=VCFv4.1 +##INFO= +##FORMAT= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FILTER= +##FILTER= +##contig= +##contig= +##contig= +##contig= +##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta +##readme=AAAAAA +##readme=BBBBBB +##INFO= +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B +1 3000150 . C T 59.2 PASS AN=4;AC=2 GT:GQ 0/1:245 0/1:245 +1 3000151 . C T 59.2 PASS AN=4;AC=2 GT:DP:GQ 0/1:32:245 0/1:32:245 +1 3062915 id3D GTTT G 12.9 q10 DP4=1,2,3,4;AN=4;AC=2;INDEL;STR=test GT:GQ:DP:GL 0/1:25:35:-20,-5,-20 0/1:45:11:-20,-5,-20 +1 3062915 idSNP G T,C 12.6 test TEST=5;DP4=1,2,3,4;AN=3;AC=1,1 GT:TT:GQ:DP:GL 0/1:0,1:409:35:-20,-5,-20,-20,-5,-20 2:0,1:409:35:-20,-5,-20 +1 3106154 . CAAA C 342 PASS AN=4;AC=2 GT:GQ:DP 0/1:245:32 0/1:25:300 +1 3106154 . C CT 59.2 PASS AN=4;AC=2 GT:GQ:DP 0/1:25:12 0/1:245:310 +1 3157410 . GA G 90.6 q10 AN=4;AC=4 GT:GQ:DP 1/1:21:21 1/1:21:21 +1 3162006 . GAA G 60.2 PASS AN=4;AC=2 GT:GQ:DP 0/1:212:22 0/1:212:22 +1 3177144 . G T 45 PASS AN=4;AC=2 GT:GQ:DP 0/0:150:30 1/1:150:30 +1 3177144 . G . 45 PASS AN=4;AC=0 GT:GQ:DP 0/0:150:30 0/0:150:30 +1 3184885 . TAAAA TA,T 61.5 PASS AN=4;AC=2,2 GT:GQ:DP 1/2:12:10 1/2:12:20 +2 3199812 . G GTT,GT 82.7 PASS AN=4;AC=2,2 GT:GQ:DP 1/2:322:20 1/2:322:10 +3 3212016 . CTT C,CT 79 PASS AN=4;AC=2,2 GT:GQ:DP 1/2:91:26 1/2:91:26 +4 3258448 . TACACACAC T 59.9 PASS AN=4;AC=2 GT 0/1 0/1 diff --git a/test/filter.3.out b/test/filter.3.out new file mode 100644 index 0000000..1663d0f --- /dev/null +++ b/test/filter.3.out @@ -0,0 +1 @@ +3162007 q20 . 0/1 2 diff --git a/test/filter.3.vcf b/test/filter.3.vcf new file mode 100644 index 0000000..24c57e8 --- /dev/null +++ b/test/filter.3.vcf @@ -0,0 +1,42 @@ +##fileformat=VCFv4.2 +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##SAMPLE=\") quoting nonsense where double brackets would do just fine",softwareName=,softwareVer=<119,65>,softwareParam=<.>,MetadataResource=http://somewhere.com/path> +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FILTER= +##contig= +##contig= +##contig= +##contig= +##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B +1 3162006 . GAA G,GA 238 q20 DP=19;AN=4;AC=1,1;XRF=1e6,2e6,3e6;XRI=1111,2222,3333;XRS=ABC,DEF,GHI;XAF=1e6,2e6;XAI=1111,2222;XAS=ABC,DEF;XGF=1e6,2e6,3e6,4e6,5e6,6e6;XGI=11,22,33,44,55,66;XGS=ABC,DEF,GHI,JKL,MNO,PQR;TXT=ABC,DEF,GHI GT:GQ:DP:STR 0/1:589:19:XX 0/2:1:1:YY +1 3162007 . TAGGG CAGGG,CAGGT 238 q20 AO=52101,113;CIGAR=1X4M,1X3M1X;TXT0=text GT:FGS:FGI:FGF:FAS:FAI:FAF:FRS:FRI:FRF 0/1:AAAAAA,BBBBB,CCCC,DDD,EE,F:1,2,3,4,5,6:1e-1,2e-2,3e-3,4e-4,5e-5,6e-6:AAA,B:1,2:1e-1,2e-2:A,BB,CCC:1,2,3:1e-1,2e-2,3e-3 2:AAAAAA,BBB,C:1,2,3:1e-1,2e-2,3e-3:AAA,B:1,2:1e-1,2e-2:A,BB,CCC:1,2,3:1e-1,2e-2,3e-3 diff --git a/test/filter.4.out b/test/filter.4.out new file mode 100644 index 0000000..4184aea --- /dev/null +++ b/test/filter.4.out @@ -0,0 +1,2 @@ +3162006 XX 19 0/1 0/2 +3162007 q20 . 0/1 2 diff --git a/test/filter.4.vcf b/test/filter.4.vcf new file mode 100644 index 0000000..78ce13a --- /dev/null +++ b/test/filter.4.vcf @@ -0,0 +1,10 @@ +##fileformat=VCFv4.1 +##contig= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT sample1 sample2 +chr1 1 . A T 100 . TEST1=10;TEST2=10 GT:TEST3:TEST4 0/1:10:10 0/1:30:30 +chr1 2 . A T 100 . TEST1=50;TEST2=50 GT:TEST3:TEST4 0/1:20:20 0/1:40:40 diff --git a/test/filter.5.out b/test/filter.5.out new file mode 100644 index 0000000..311562e --- /dev/null +++ b/test/filter.5.out @@ -0,0 +1,2 @@ +3162006 q20;XX 19 0/1 0/2 +3162007 q20 . 0/1 2 diff --git a/test/filter.6.out b/test/filter.6.out new file mode 100644 index 0000000..0cb0aa4 --- /dev/null +++ b/test/filter.6.out @@ -0,0 +1,2 @@ +3162006 XX 19 0/1 0/2 +3162007 PASS . 0/1 2 diff --git a/test/filter.7.out b/test/filter.7.out new file mode 100644 index 0000000..00a3c15 --- /dev/null +++ b/test/filter.7.out @@ -0,0 +1,2 @@ +3162006 q20;XX 19 0/1 0/2 +3162007 PASS . 0/1 2 diff --git a/test/filter.8.out b/test/filter.8.out new file mode 100644 index 0000000..bb8cac6 --- /dev/null +++ b/test/filter.8.out @@ -0,0 +1 @@ +3177144 2 0/0 1/1 diff --git a/test/filter.9.out b/test/filter.9.out new file mode 100644 index 0000000..3bf2f5c --- /dev/null +++ b/test/filter.9.out @@ -0,0 +1 @@ +3177144 0 0/0 0/0 diff --git a/test/fixploidy.out b/test/fixploidy.out new file mode 100644 index 0000000..07e7cd8 --- /dev/null +++ b/test/fixploidy.out @@ -0,0 +1,18 @@ +##fileformat=VCFv4.1 +##FILTER= +##contig= +##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta +##INFO= +##INFO= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FILTER= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B C +1 3000001 xx C CT 11 PASS FLAG;IINT=11;IFLT=1.1;ISTR=xxx GT:FINT:FFLT:FSTR .:11:1.1:xxx 0:11:1.1:x 0|0:11:1.1:x +1 3000002 . C CTT . . . GT ././. ./././. .|.|.|.|. +1 3000003 xx C CTTT 11 q11 FLAG;IINT=.;IFLT=.;ISTR=. GT:FINT:FFLT:FSTR 0/0:.:.:. 0/0:.:.:. 0|0:.:.:. +1 3000004 xx C CTTTT 11 q11 FLAG;IINT=11;IFLT=1.1;ISTR=xxx GT:FINT:FFLT:FSTR 0/0/0/0/0/0:11:1.1:x 0/0/0/0/0/0/0:11:1.1:xxx 0|0|0|0|0|0|0|0:11:1.1:xxx diff --git a/test/fixploidy.ploidy b/test/fixploidy.ploidy new file mode 100644 index 0000000..268c616 --- /dev/null +++ b/test/fixploidy.ploidy @@ -0,0 +1,9 @@ +1 3000001 3000001 X 0 +1 3000001 3000001 Y 1 +1 3000001 3000001 Z 2 +1 3000002 3000002 X 3 +1 3000002 3000002 Y 4 +1 3000002 3000002 Z 5 +1 3000004 3000004 X 6 +1 3000004 3000004 Y 7 +1 3000004 3000004 Z 8 diff --git a/test/fixploidy.samples b/test/fixploidy.samples new file mode 100644 index 0000000..f364918 --- /dev/null +++ b/test/fixploidy.samples @@ -0,0 +1,3 @@ +A X +B Y +C Z diff --git a/test/fixploidy.vcf b/test/fixploidy.vcf new file mode 100644 index 0000000..0c789b2 --- /dev/null +++ b/test/fixploidy.vcf @@ -0,0 +1,17 @@ +##fileformat=VCFv4.1 +##contig= +##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta +##INFO= +##INFO= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FILTER= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B C +1 3000001 xx C CT 11 PASS FLAG;IINT=11;IFLT=1.1;ISTR=xxx GT:FINT:FFLT:FSTR 0/0:11:1.1:xxx 0/0:11:1.1:x 0|0:11:1.1:x +1 3000002 . C CTT . . . GT ./. ./. .|. +1 3000003 xx C CTTT 11 q11 FLAG;IINT=.;IFLT=.;ISTR=. GT:FINT:FFLT:FSTR 0/0:.:.:. 0/0:.:.:. 0|0:.:.:. +1 3000004 xx C CTTTT 11 q11 FLAG;IINT=11;IFLT=1.1;ISTR=xxx GT:FINT:FFLT:FSTR 0/0:11:1.1:x 0/0:11:1.1:xxx 0|0:11:1.1:xxx diff --git a/test/fixref.1.out b/test/fixref.1.out new file mode 100644 index 0000000..250e42e --- /dev/null +++ b/test/fixref.1.out @@ -0,0 +1,31 @@ +##fileformat=VCFv4.2 +##FILTER= +##FORMAT= +##contig= +##contig= +##contig= +##contig= +##contig= +##contig= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT XY00001 XY00002 +1 105 . T G,A 999 PASS . GT 1/2 1/2 +2 1 . G ACGT 999 PASS . GT 1/0 1/0 +2 101 . A C 999 PASS . GT 0/0 0/0 +2 114 . TC TTCC,TTC 999 PASS . GT 1/2 1/2 +2 115 . C T 999 PASS . GT 1/1 1/1 +20 3 . G CT 999 PASS . GT 0/1 0/1 +20 3 . GATG GACT 999 PASS . GT 1/0 1/0 +20 5 . TGGG TAC,TG,TGGGG,AC . PASS . GT 1/2 1/2 +20 59 . AG . 999 PASS . GT 0/0 0/0 +20 80 . CACAG CACAT 999 PASS . GT 0/1 0/1 +20 81 . A C 999 PASS . GT 0/1 0/1 +20 95 . TCACCG ACACCG 999 PASS . GT 0/1 0/1 +20 95 . TCACCG AAAAAA 999 PASS . GT 0/1 0/1 +20 273 . CAAAAAAAAAAAAAAAAAAAAA CAAAAAAAAAAAAAAAAAAAAAAA,CAAAAAAAAAAAAAAAAAAAAAAAA 999 PASS . GT 1/2 1/2 +20 274 . AAAAAAAAA AAAAAAAAAAAAAAAAAAA 999 PASS . GT ./. ./. +20 275 . A C,G 999 PASS . GT 2 2 +20 278 . AAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAA 999 PASS . GT ./. ./. +3 10 . GTGGAC GTGGACACAC,GTGGACAC,GTGGACACACAC,GTGG,GTGGACACACACAC,ATGGACACACAC 999 PASS . GT ./. ./. +3 15 . CACA CAC 999 PASS . GT ./. ./. +4 21 . ATTTTTTTTTTTTTTTC ATTTTTTTTTTTTTTC,ATTTTTTTTTTTTTTTT,ATTTTTTTTTTTTTTTTC 999 PASS . GT ./. ./. +5 22 . A AGA 999 PASS . GT ./. ./. diff --git a/test/fixref.vcf b/test/fixref.vcf new file mode 100644 index 0000000..8ab2a80 --- /dev/null +++ b/test/fixref.vcf @@ -0,0 +1,31 @@ +##fileformat=VCFv4.2 +##FILTER= +##FORMAT= +##contig= +##contig= +##contig= +##contig= +##contig= +##contig= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT XY00001 XY00002 +1 105 . T G,A 999 PASS . GT 1/2 1/2 +2 1 . G ACGT 999 PASS . GT 1/0 1/0 +2 101 . C A 999 PASS . GT 1/1 1/1 +2 114 . TC TTCC,TTC 999 PASS . GT 1/2 1/2 +2 115 . T C 999 PASS . GT 0/0 0/0 +20 3 . G CT 999 PASS . GT 0/1 0/1 +20 3 . GATG GACT 999 PASS . GT 1/0 1/0 +20 5 . TGGG TAC,TG,TGGGG,AC . PASS . GT 1/2 1/2 +20 59 . AG . 999 PASS . GT 0/0 0/0 +20 80 . CACAG CACAT 999 PASS . GT 0/1 0/1 +20 81 . A C 999 PASS . GT 0/1 0/1 +20 95 . TCACCG ACACCG 999 PASS . GT 0/1 0/1 +20 95 . TCACCG AAAAAA 999 PASS . GT 0/1 0/1 +20 273 . CAAAAAAAAAAAAAAAAAAAAA CAAAAAAAAAAAAAAAAAAAAAAA,CAAAAAAAAAAAAAAAAAAAAAAAA 999 PASS . GT 1/2 1/2 +20 274 . AAAAAAAAA AAAAAAAAAAAAAAAAAAA 999 PASS . GT ./. ./. +20 275 . A C,G 999 PASS . GT 2 2 +20 278 . AAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAA 999 PASS . GT ./. ./. +3 10 . GTGGAC GTGGACACAC,GTGGACAC,GTGGACACACAC,GTGG,GTGGACACACACAC,ATGGACACACAC 999 PASS . GT ./. ./. +3 15 . CACA CAC 999 PASS . GT ./. ./. +4 21 . ATTTTTTTTTTTTTTTC ATTTTTTTTTTTTTTC,ATTTTTTTTTTTTTTTT,ATTTTTTTTTTTTTTTTC 999 PASS . GT ./. ./. +5 22 . A AGA 999 PASS . GT ./. ./. diff --git a/test/guess-ploidy.GL.out b/test/guess-ploidy.GL.out new file mode 100644 index 0000000..ec90554 --- /dev/null +++ b/test/guess-ploidy.GL.out @@ -0,0 +1,4 @@ +# [1]SEX [2]Sample [3]Predicted sex [4]log P(Haploid)/nSites [5]log P(Diploid)/nSites [6]nSites [7]Score: F < 0 < M ($4-$5) +SEX NA00001 M -0.592820 -1.185639 4 0.592819 +SEX NA00002 M -0.318166 -0.636333 4 0.318166 +SEX NA00003 F -14.297587 -0.750505 3 -13.547082 diff --git a/test/guess-ploidy.PL.out b/test/guess-ploidy.PL.out new file mode 100644 index 0000000..ec90554 --- /dev/null +++ b/test/guess-ploidy.PL.out @@ -0,0 +1,4 @@ +# [1]SEX [2]Sample [3]Predicted sex [4]log P(Haploid)/nSites [5]log P(Diploid)/nSites [6]nSites [7]Score: F < 0 < M ($4-$5) +SEX NA00001 M -0.592820 -1.185639 4 0.592819 +SEX NA00002 M -0.318166 -0.636333 4 0.318166 +SEX NA00003 F -14.297587 -0.750505 3 -13.547082 diff --git a/test/gvcf.fa b/test/gvcf.fa new file mode 100644 index 0000000..45c4d5b --- /dev/null +++ b/test/gvcf.fa @@ -0,0 +1,9 @@ +>22 +NNNNNNNNCCTTGGCCAAGTCACTTCCTCCTTCAGGAACATTGCAGTGGGCCTAAGTGCC +TCCTCTCGGGACTGGTATGGGGACGGTCATGCAATCTGGACAACATTCACCTTTAAAAGT +TTATTGATCTTTTGTGACATGCACGTGGGTTCCCAGTAGCAAGAAACTAAAGGGTCGCAG +GCCGGTTTCTGCTAATTTCTTTAATTCCAAGACAGTCTCAAATATTTTCTTATTAACTTC +CTGGAGGGAGGCTTATCATTCTCTCTTTTGGATGATTCTAAGTACCAGCTAAAATACAGC +TATCATTCATTTTCCTTGATTTGGGAGCCTAATTTCTTTAATTTAGTATGCAAGAAAACC +AATTTGGAAATATCAACTGTTTTGGAAACCTTAGACCTAGGTCATCCTTAGTAAGATCTT +CCCATTTATATAAATACTTGCAAGTAGTAGTGCCATAATT diff --git a/test/gvcf.fa.fai b/test/gvcf.fa.fai new file mode 100644 index 0000000..4f07c21 --- /dev/null +++ b/test/gvcf.fa.fai @@ -0,0 +1 @@ +22 460 4 60 61 diff --git a/test/gvcf.merge.1.out b/test/gvcf.merge.1.out new file mode 100644 index 0000000..bd05d85 --- /dev/null +++ b/test/gvcf.merge.1.out @@ -0,0 +1,30 @@ +##fileformat=VCFv4.1 +##FILTER= +##FILTER= +##FILTER= +##FILTER= +##contig= +##contig= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##contig= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT G06 D05 H09 +chr1 10106 . C . 0 LowGQX BLOCKAVG_min30p3a;AN=2 GT:GQX:DP:DPF ./.:.:.:. 0/0:12:5:0 ./.:.:.:. +chr1 10107 . C . 0 LowGQX;HighDPFRatio BLOCKAVG_min30p3a;AN=4 GT:GQX:DP:DPF .:.:0:1 0/0:12:5:0 0/0:5:2:0 +chr1 10108 . N . 0 LowGQX;HighDPFRatio END=10110;BLOCKAVG_min30p3a;AN=2 GT:GQX:DP:DPF .:.:0:1 ./.:.:.:. 0/0:5:2:0 +chr1 10111 . N . 0 LowGQX END=10120;BLOCKAVG_min30p3a;AN=2 GT:GQX:DP:DPF ./.:.:.:. ./.:.:.:. 0/0:5:2:0 diff --git a/test/gvcf.merge.1.vcf b/test/gvcf.merge.1.vcf new file mode 100644 index 0000000..4ea7f0f --- /dev/null +++ b/test/gvcf.merge.1.vcf @@ -0,0 +1,26 @@ +##fileformat=VCFv4.1 +##FILTER= +##FILTER= +##FILTER= +##FILTER= +##contig= +##contig= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT G06 +chr1 10107 . C . 0.00 LowGQX;HighDPFRatio END=10110;BLOCKAVG_min30p3a GT:GQX:DP:DPF .:.:0:1 diff --git a/test/gvcf.merge.2.vcf b/test/gvcf.merge.2.vcf new file mode 100644 index 0000000..bebd0e2 --- /dev/null +++ b/test/gvcf.merge.2.vcf @@ -0,0 +1,26 @@ +##fileformat=VCFv4.1 +##FILTER= +##FILTER= +##FILTER= +##FILTER= +##contig= +##contig= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT D05 +chr1 10106 . C . 0.00 LowGQX END=10107;BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:12:5:0 diff --git a/test/gvcf.merge.3.vcf b/test/gvcf.merge.3.vcf new file mode 100644 index 0000000..f79ff11 --- /dev/null +++ b/test/gvcf.merge.3.vcf @@ -0,0 +1,26 @@ +##fileformat=VCFv4.1 +##FILTER= +##FILTER= +##FILTER= +##FILTER= +##contig= +##contig= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT H09 +chr1 10107 . C . 0.00 LowGQX END=10120;BLOCKAVG_min30p3a GT:GQX:DP:DPF 0/0:5:2:0 diff --git a/test/idx.out b/test/idx.out new file mode 100644 index 0000000..66889bc --- /dev/null +++ b/test/idx.out @@ -0,0 +1,4 @@ +11 135006516 2 +20 63025520 7 +X 155270560 4 +Y 59373566 2 diff --git a/test/idx.vcf b/test/idx.vcf new file mode 100644 index 0000000..ba8772d --- /dev/null +++ b/test/idx.vcf @@ -0,0 +1,22 @@ +##fileformat=VCFv4.1 +##contig= +##contig= +##contig= +##contig= +##contig= +#CHROM POS ID REF ALT QUAL FILTER INFO +11 2343543 . A . 999 PASS . +11 5464562 . C T 999 PASS . +20 76962 . T C 999 PASS . +20 126310 . ACC A 999 PASS . +20 138125 . G T 999 PASS . +20 138148 . C T 999 PASS . +20 271225 . T TTTA,TA 999 PASS . +20 304568 . C T 999 PASS . +20 326891 . A AC 999 PASS . +X 2928329 . C T 999 PASS . +X 2933066 . G C 999 PASS . +X 2942109 . T C 999 PASS . +X 3048719 . T C 999 PASS . +Y 8657215 . C A 999 PASS . +Y 10011673 . G A 999 PASS . diff --git a/test/idx_count.out b/test/idx_count.out new file mode 100644 index 0000000..60d3b2f --- /dev/null +++ b/test/idx_count.out @@ -0,0 +1 @@ +15 diff --git a/test/isec.a.vcf b/test/isec.a.vcf new file mode 100644 index 0000000..fe7f872 --- /dev/null +++ b/test/isec.a.vcf @@ -0,0 +1,27 @@ +##fileformat=VCFv4.1 +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FILTER= +##test= +##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta +##INFO= +##INFO= +##readme=AAAAAA +##readme=BBBBBB +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A +1 3062915 . GTTT G 1806 q10 DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 +1 3062915 . G T 1806 q10 DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 +1 3106154 . CAAA C 1792 PASS DP=32;AN=2;AC=1 GT:GQ:DP 0/1:245:32 +1 3106154 . C T,CT 1792 PASS DP=32;AN=2;AC=1 GT:GQ:DP 0/1:245:32 +1 3157410 . GA G 628 q10 DP=21;AN=2;AC=2 GT:GQ:DP 1/1:21:21 +1 3162006 . GAA G 1016 PASS DP=22;AN=2;AC=1 GT:GQ:DP 0/1:212:22 +1 3177144 . GT G 727 PASS DP=30;AN=2;AC=1 GT:GQ:DP 0/1:150:30 +1 3184885 . TAAAA TA,T 246 PASS DP=10;AN=2;AC=1,1 GT:GQ:DP 1/2:12:10 +2 3199812 . G GTT,GT 481 PASS DP=26;AN=2;AC=1,1 GT:GQ:DP 1/2:322:26 +3 3212016 . CTT C,CT 565 PASS DP=26;AN=2;AC=1,1 GT:GQ:DP 1/2:91:26 +4 3212016 . TACACACAC T 325 PASS DP=31;AN=2;AC=1 GT:GQ:DP 0/1:325:31 +4 3258448 . TACACACAC T 325 PASS DP=31;AN=2;AC=1 GT:GQ:DP 0/1:325:31 diff --git a/test/isec.ab.C.out b/test/isec.ab.C.out new file mode 100644 index 0000000..fdf3eff --- /dev/null +++ b/test/isec.ab.C.out @@ -0,0 +1,3 @@ +2 3199812 G GTT,GT 10 +3 3212016 CTT C,CT 10 +4 3258448 TACACACAC T 10 diff --git a/test/isec.ab.any.out b/test/isec.ab.any.out new file mode 100644 index 0000000..d1b19f7 --- /dev/null +++ b/test/isec.ab.any.out @@ -0,0 +1,9 @@ +1 3062915 GTTT G 11 +1 3062915 G T 11 +1 3106154 CAAA C 11 +1 3106154 C T,CT 11 +1 3157410 GA G 11 +1 3162006 GAA G 11 +1 3177144 GT G 11 +1 3184885 TAAAA TA,T 11 +4 3212016 TACACACAC T 11 diff --git a/test/isec.ab.both.out b/test/isec.ab.both.out new file mode 100644 index 0000000..d1b19f7 --- /dev/null +++ b/test/isec.ab.both.out @@ -0,0 +1,9 @@ +1 3062915 GTTT G 11 +1 3062915 G T 11 +1 3106154 CAAA C 11 +1 3106154 C T,CT 11 +1 3157410 GA G 11 +1 3162006 GAA G 11 +1 3177144 GT G 11 +1 3184885 TAAAA TA,T 11 +4 3212016 TACACACAC T 11 diff --git a/test/isec.ab.flt.out b/test/isec.ab.flt.out new file mode 100644 index 0000000..26dc93d --- /dev/null +++ b/test/isec.ab.flt.out @@ -0,0 +1,2 @@ +1 3157410 GA G 11 +1 3177144 GT G 11 diff --git a/test/isec.ab.out b/test/isec.ab.out new file mode 100644 index 0000000..20cbac6 --- /dev/null +++ b/test/isec.ab.out @@ -0,0 +1,3 @@ +1 3157410 GA G 11 +1 3162006 GAA G 11 +1 3177144 GT G 11 diff --git a/test/isec.b.vcf b/test/isec.b.vcf new file mode 100644 index 0000000..2255325 --- /dev/null +++ b/test/isec.b.vcf @@ -0,0 +1,27 @@ +##fileformat=VCFv4.1 +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FILTER= +##contig= +##contig= +##contig= +##contig= +##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT B +1 3062915 . G A 376 q20 DP=14;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:376:14:-10,0,-10 +1 3062915 . GTTT GT 376 q20 DP=14;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:376:14:-10,0,-10 +1 3106154 . C T 677 PASS DP=15;AN=2;AC=1 GT:GQ:DP:GL 0/1:277:15:-10,0,-10 +1 3106154 . CAAAA C 677 PASS DP=15;AN=2;AC=1 GT:GQ:DP:GL 0/1:277:15:-10,0,-10 +1 3157410 . GA G 249 PASS DP=11;AN=2;AC=1 GT:GQ:DP 0/1:49:11 +1 3162006 . GAA G 663 PASS DP=19;AN=2;AC=1 GT:GQ:DP 0/1:589:19 +1 3177144 . GT G 460 PASS DP=24;AN=2;AC=1 GT:GQ:DP 0/1:236:24 +1 3184885 . TAAA T 598 PASS DP=16;AN=2;AC=1 GT:GQ:DP 0/1:435:16 +2 3188209 . GA G 162 . DP=15;AN=2;AC=1 GT:GQ:DP 0/1:162:15 +3 3199812 . G GTT,GT 353 PASS DP=19;AN=2;AC=1,1 GT:GQ:DP 1/2:188:19 +4 3212016 . CTT C 677 q20 DP=15;AN=2;AC=1 GT:GQ:DP 0/1:158:15 diff --git a/test/isec.tab b/test/isec.tab new file mode 100644 index 0000000..6093291 --- /dev/null +++ b/test/isec.tab @@ -0,0 +1,5 @@ +1 3062915 3062915 +1 3106154 3106154 +1 3157410 3162006 +1 3177144 3177144 +4 3212016 3212016 diff --git a/test/isec.tab.out b/test/isec.tab.out new file mode 100644 index 0000000..1b2e0ed --- /dev/null +++ b/test/isec.tab.out @@ -0,0 +1,28 @@ +##fileformat=VCFv4.1 +##FILTER= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FILTER= +##test= +##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta +##INFO= +##INFO= +##readme=AAAAAA +##readme=BBBBBB +##contig= +##contig= +##contig= +##contig= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A +1 3062915 . GTTT G 1806 q10 DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 +1 3062915 . G T 1806 q10 DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 +1 3106154 . CAAA C 1792 PASS DP=32;AN=2;AC=1 GT:GQ:DP 0/1:245:32 +1 3106154 . C T,CT 1792 PASS DP=32;AN=2;AC=1 GT:GQ:DP 0/1:245:32 +1 3157410 . GA G 628 q10 DP=21;AN=2;AC=2 GT:GQ:DP 1/1:21:21 +1 3162006 . GAA G 1016 PASS DP=22;AN=2;AC=1 GT:GQ:DP 0/1:212:22 +1 3177144 . GT G 727 PASS DP=30;AN=2;AC=1 GT:GQ:DP 0/1:150:30 +4 3212016 . TACACACAC T 325 PASS DP=31;AN=2;AC=1 GT:GQ:DP 0/1:325:31 diff --git a/test/large_chrom.20.1.2147483647.out b/test/large_chrom.20.1.2147483647.out new file mode 100644 index 0000000..637e62c --- /dev/null +++ b/test/large_chrom.20.1.2147483647.out @@ -0,0 +1,9 @@ +chr20 76962 . T C 999 PASS . +chr20 126310 . ACC A 999 PASS . +chr20 138125 . G T 999 PASS . +chr20 138148 . C T 999 PASS . +chr20 271225 . T TTTA,TA 999 PASS . +chr20 304568 . C T 999 PASS . +chr20 620255100 . AG T 999 PASS . +chr20 630255200 . G C 999 PASS . +chr20 2147483647 . A T 999 PASS . diff --git a/test/large_chrom_csi_limit.20.1.2147483647.out b/test/large_chrom_csi_limit.20.1.2147483647.out new file mode 100644 index 0000000..637e62c --- /dev/null +++ b/test/large_chrom_csi_limit.20.1.2147483647.out @@ -0,0 +1,9 @@ +chr20 76962 . T C 999 PASS . +chr20 126310 . ACC A 999 PASS . +chr20 138125 . G T 999 PASS . +chr20 138148 . C T 999 PASS . +chr20 271225 . T TTTA,TA 999 PASS . +chr20 304568 . C T 999 PASS . +chr20 620255100 . AG T 999 PASS . +chr20 630255200 . G C 999 PASS . +chr20 2147483647 . A T 999 PASS . diff --git a/test/large_chrom_csi_limit.vcf b/test/large_chrom_csi_limit.vcf new file mode 100644 index 0000000..f8a3661 --- /dev/null +++ b/test/large_chrom_csi_limit.vcf @@ -0,0 +1,18 @@ +##fileformat=VCFv4.2 +##reference=file:///seq/references/long_chrom.fasta +##FILTER= +##contig= +##contig= +#CHROM POS ID REF ALT QUAL FILTER INFO +chr11 2343543 . A . 999 PASS . +chr11 5464562 . C T 999 PASS . +chr11 116870911 . C G 999 PASS . +chr20 76962 . T C 999 PASS . +chr20 126310 . ACC A 999 PASS . +chr20 138125 . G T 999 PASS . +chr20 138148 . C T 999 PASS . +chr20 271225 . T TTTA,TA 999 PASS . +chr20 304568 . C T 999 PASS . +chr20 620255100 . AG T 999 PASS . +chr20 630255200 . G C 999 PASS . +chr20 2147483647 . A T 999 PASS . diff --git a/test/many.alleles.trim.out b/test/many.alleles.trim.out new file mode 100644 index 0000000..7b622e1 --- /dev/null +++ b/test/many.alleles.trim.out @@ -0,0 +1,10 @@ +##fileformat=VCFv4.1 +##FILTER= +##contig= +##FORMAT= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT SRR1528791 +chr7 142459798 . CCATCTCTCTGCCCA CCATCTCTCTCCCCG . . AC=2;AN=2 GT 1/1 +chr7 142459798 . CCATCTCTCTGCCCA CCATCTCTCTCCCCG . . AC=2;AN=2 GT 1/1 +chr7 142459798 . CCATCTCTCTGCCCA CCATCTCTCTCCCCG . . AC=2;AN=2 GT 1/1 diff --git a/test/many.alleles.vcf b/test/many.alleles.vcf new file mode 100644 index 0000000..491bc89 --- /dev/null +++ b/test/many.alleles.vcf @@ -0,0 +1,7 @@ +##fileformat=VCFv4.1 +##contig= +##FORMAT= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT SRR1528791 +chr7 142459798 . CCATCTCTCTGCCCA CCATCTCTCTCCCCC,CCATCTCTCTCCCCG,CCTTCTCTCTGCCCC,CCCTCTCTCTCCCCC,CCACCTCTCTGCCCC,CCACCCCTCTGCCCA,CCACCTCCCTCCCCC,CCACCTCCCTGCCCA,CCACCTCTCGGCCCC,CCACCTCTCGGCCCA,CCACCTCTCTCCCCC,CCACCTCTCTCCCCA,CCATCCCCCTCCCCC,CCATCCCCCTGCCCC,CCATCCCCCTGCCCA,CCATCCCTCGGCCCC,CCATCCCTCGGCCCA,CCATCCCTCTCCCCC,CCATCCCTCTCCCCA,CCATCCCTCTGCCCC,CCATCTCCCGGCCCC,CCATCTCCCGGCCCA,CCATCTCCCGCCCCC,CCATCTCCCTCCCCC,CCATCTCCCTCCCCA,CCATCTCCCTGCCCC,CCATCTCTCGGCCCC,CCATCTCTCCCCCCC,CCATCTCTCGCCCCC,CCATCTCTGGGCCCA,CCATCTCTCCCCCCA,CCATCTCTCGCCCCA,CCATCTCTCTCCCCA . . . GT 2/2 +chr7 142459798 . CCATCTCTCTGCCCA CCATCTCTCTCCCCC,CCATCTCTCTCCCCG,CCTTCTCTCTGCCCC,CCCTCTCTCTCCCCC,CCACCTCTCTGCCCC,CCACCCCTCTGCCCA,CCACCTCCCTCCCCC,CCACCTCCCTGCCCA,CCACCTCTCGGCCCC,CCACCTCTCGGCCCA,CCACCTCTCTCCCCC,CCACCTCTCTCCCCA,CCATCCCCCTCCCCC,CCATCCCCCTGCCCC,CCATCCCCCTGCCCA,CCATCCCTCGGCCCC,CCATCCCTCGGCCCA,CCATCCCTCTCCCCC,CCATCCCTCTCCCCA,CCATCCCTCTGCCCC,CCATCTCCCGGCCCC,CCATCTCCCGGCCCA,CCATCTCCCGCCCCC,CCATCTCCCTCCCCC,CCATCTCCCTCCCCA,CCATCTCCCTGCCCC,CCATCTCTCGGCCCC,CCATCTCTCCCCCCC,CCATCTCTCGCCCCC,CCATCTCTGGGCCCA,CCATCTCTCCCCCCA,CCATCTCTCGCCCCA,CCATCTCTCTCCCCA,CCTTCTCTCTGCCCC . . . GT 2/2 +chr7 142459798 . CCATCTCTCTGCCCA CCATCTCTCTCCCCC,CCATCTCTCTCCCCG,CCTTCTCTCTGCCCC,CCCTCTCTCTCCCCC,CCACCTCTCTGCCCC,CCACCCCTCTGCCCA,CCACCTCCCTCCCCC,CCACCTCTCGGCCCC,CCACCTCTCGGCCCA,CCACCTCTCTCCCCC,CCACCTCTCTCCCCA,CCATCCCCCTCCCCC,CCATCCCCCTGCCCC,CCATCCCCCTGCCCA,CCATCCCTCGGCCCC,CCATCCCTCGGCCCA,CCATCCCTCTCCCCC,CCATCCCTCTCCCCA,CCATCCCTCTGCCCC,CCATCTCCCGGCCCC,CCATCTCCCGGCCCA,CCATCTCCCGCCCCC,CCATCTCCCTCCCCC,CCATCTCCCTCCCCA,CCATCTCCCTGCCCC,CCATCTCTCGGCCCC,CCATCTCTCCCCCCC,CCATCTCTCGCCCCC,CCATCTCTGGGCCCA,CCATCTCTCCCCCCA,CCATCTCTCGCCCCA,CCATCTCTCTCCCCA,CCTTCTCTCTGCCCC,CCTTCTCTCTGCCCC,CCTTCTCTCTGCCCC,CCTTCTCTCTGCCCC,CCTTCTCTCTGCCCC,CCTTCTCTCTGCCCC,CCTTCTCTCTGCCCC,CCTTCTCTCTGCCCC,CCTTCTCTCTGCCCC,CCTTCTCTCTGCCCC,CCTTCTCTCTGCCCC,CCTTCTCTCTGCCCC,CCTTCTCTCTGCCCC,CCTTCTCTCTGCCCC,CCTTCTCTCTGCCCC,CCTTCTCTCTGCCCC,CCTTCTCTCTGCCCC,CCTTCTCTCTGCCCC,CCTTCTCTCTGCCCC,CCTTCTCTCTGCCCC,CCTTCTCTCTGCCCC,CCTTCTCTCTGCCCC,CCTTCTCTCTGCCCC,CCTTCTCTCTGCCCC,CCTTCTCTCTGCCCC,CCTTCTCTCTGCCCC,CCTTCTCTCTGCCCC,CCTTCTCTCTGCCCC,CCTTCTCTCTGCCCC,CCTTCTCTCTGCCCC,CCTTCTCTCTGCCCC . . . GT 2/2 diff --git a/test/mendelian.1.out b/test/mendelian.1.out new file mode 100644 index 0000000..414f79b --- /dev/null +++ b/test/mendelian.1.out @@ -0,0 +1,9 @@ +##fileformat=VCFv4.2 +##FILTER= +##FORMAT= +##contig= +##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT mom1 dad1 child1 mom2 dad2 child2 +1 100 . A G 100 PASS . GT ./. ./. ./. 1/1 0/1 1/1 +1 101 . A T 100 PASS . GT 0/0 0/1 0/1 1/1 0/1 1/0 +1 102 . A T 100 PASS . GT 0/0 0/1 0/1 1/1 0/1 1/0 diff --git a/test/mendelian.2.out b/test/mendelian.2.out new file mode 100644 index 0000000..81155ae --- /dev/null +++ b/test/mendelian.2.out @@ -0,0 +1,8 @@ +##fileformat=VCFv4.2 +##FILTER= +##FORMAT= +##contig= +##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT mom1 dad1 child1 mom2 dad2 child2 +1 101 . A T 100 PASS . GT 0/0 0/1 0/1 1/1 0/1 1/0 +1 102 . A T 100 PASS . GT 0/0 0/1 0/1 1/1 0/1 1/0 diff --git a/test/mendelian.3.out b/test/mendelian.3.out new file mode 100644 index 0000000..9ea430a --- /dev/null +++ b/test/mendelian.3.out @@ -0,0 +1,7 @@ +##fileformat=VCFv4.2 +##FILTER= +##FORMAT= +##contig= +##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT mom1 dad1 child1 mom2 dad2 child2 +1 100 . A G 100 PASS . GT 0/0 0/0 1/1 1/1 0/1 1/1 diff --git a/test/mendelian.vcf b/test/mendelian.vcf new file mode 100644 index 0000000..c43ba07 --- /dev/null +++ b/test/mendelian.vcf @@ -0,0 +1,8 @@ +##fileformat=VCFv4.2 +##FORMAT= +##contig= +##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT mom1 dad1 child1 mom2 dad2 child2 +1 100 . A G 100 PASS . GT 0/0 0/0 1/1 1/1 0/1 1/1 +1 101 . A T 100 PASS . GT 0/0 0/1 0/1 1/1 0/1 1/0 +1 102 . A T 100 PASS . GT 0/0 0/1 0/1 1/1 0/1 1/0 diff --git a/test/merge.2.a.vcf b/test/merge.2.a.vcf new file mode 100644 index 0000000..c048c08 --- /dev/null +++ b/test/merge.2.a.vcf @@ -0,0 +1,30 @@ +##fileformat=VCFv4.1 +##INFO= +##FORMAT= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FILTER= +##FILTER= +##contig= +##contig= +##contig= +##contig= +##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta +##readme=AAAAAA +##readme=BBBBBB +##INFO= +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B +1 3000000 . C CCG 59.2 PASS AN=4;AC=2 GT:GQ 0/1:245 0/1:245 +1 3000150 . C A 59.2 PASS AN=4;AC=2 GT:GQ 0/1:245 0/1:245 +1 3000151 . C A 59.2 PASS AN=4;AC=2 GT:DP:GQ 0/1:32:245 0/1:32:245 +1 3106154 . C CC 342 PASS AN=4;AC=2 GT:GQ:DP 0/1:245:32 0/1:245:32 +1 3106154 . C A 59.2 PASS AN=4;AC=2 GT:GQ:DP 0/1:245:32 0/1:245:32 +1 3200000 . C T 59.2 PASS AN=4;AC=2 GT:GQ:DP 0/1:245:32 0/1:245:32 +1 3200010 . C T 59.2 PASS AN=4;AC=2 GT:GQ:DP 0/1:245:32 0/1:245:32 +1 3200020 . C G,T 59.2 PASS AN=4;AC=2 GT:GL ./.:1,2,3,4,5,6 .:1,2,3 diff --git a/test/merge.2.all.out b/test/merge.2.all.out new file mode 100644 index 0000000..915773e --- /dev/null +++ b/test/merge.2.all.out @@ -0,0 +1,31 @@ +##fileformat=VCFv4.1 +##FILTER= +##INFO= +##FORMAT= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FILTER= +##FILTER= +##contig= +##contig= +##contig= +##contig= +##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta +##readme=AAAAAA +##readme=BBBBBB +##INFO= +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 2:A 2:B +1 3000000 . C CCG,G 59.2 PASS AN=8;AC=2,2 GT:GQ 0/1:245 0/1:245 0/2:245 0/2:245 +1 3000150 . C A,G 59.2 PASS AN=8;AC=2,2 GT:GQ 0/1:245 0/1:245 0/2:245 0/2:245 +1 3000151 . C A,G 59.2 PASS AN=8;AC=2,2 GT:DP:GQ 0/1:32:245 0/1:32:245 0/2:32:245 0/2:32:245 +1 3106154 . C CC,CCC 342 PASS AN=8;AC=2,2 GT:GQ:DP 0/1:245:32 0/1:245:32 0/2:245:32 0/2:245:32 +1 3106154 . C A,T 59.2 PASS AN=8;AC=2,2 GT:GQ:DP 0/1:245:32 0/1:245:32 0/2:245:32 0/2:245:32 +1 3200000 . C T 59.2 PASS AN=8;AC=4 GT:GQ:DP 0/1:245:32 0/1:245:32 0/1:245:32 0/1:245:32 +1 3200010 . C T,A 59.2 PASS AN=8;AC=2,2 GT:GQ:DP 0/1:245:32 0/1:245:32 0/2:245:32 0/2:245:32 +1 3200020 . C G,T 59.2 PASS AN=0;AC=0,0 GT:GL ./.:1,2,3,4,5,6 .:1,2,3 ./.:1,2,3,4,5,6 .:1,2,3 diff --git a/test/merge.2.b.vcf b/test/merge.2.b.vcf new file mode 100644 index 0000000..8700f1c --- /dev/null +++ b/test/merge.2.b.vcf @@ -0,0 +1,30 @@ +##fileformat=VCFv4.1 +##INFO= +##FORMAT= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FILTER= +##FILTER= +##contig= +##contig= +##contig= +##contig= +##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta +##readme=AAAAAA +##readme=BBBBBB +##INFO= +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B +1 3000000 . C G 59.2 PASS AN=4;AC=2 GT:GQ 0/1:245 0/1:245 +1 3000150 . C G 59.2 PASS AN=4;AC=2 GT:GQ 0/1:245 0/1:245 +1 3000151 . C G 59.2 PASS AN=4;AC=2 GT:DP:GQ 0/1:32:245 0/1:32:245 +1 3106154 . C CCC 342 PASS AN=4;AC=2 GT:GQ:DP 0/1:245:32 0/1:245:32 +1 3106154 . C T 59.2 PASS AN=4;AC=2 GT:GQ:DP 0/1:245:32 0/1:245:32 +1 3200000 . C T 59.2 PASS AN=4;AC=2 GT:GQ:DP 0/1:245:32 0/1:245:32 +1 3200010 . c A,T 59.2 PASS AN=4;AC=2 GT:GQ:DP 0/1:245:32 0/1:245:32 +1 3200020 . C T,G 59.2 PASS AN=4;AC=2 GT:GL ./.:1,4,6,2,5,3 .:1,3,2 diff --git a/test/merge.2.both.out b/test/merge.2.both.out new file mode 100644 index 0000000..67c3aae --- /dev/null +++ b/test/merge.2.both.out @@ -0,0 +1,32 @@ +##fileformat=VCFv4.1 +##FILTER= +##INFO= +##FORMAT= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FILTER= +##FILTER= +##contig= +##contig= +##contig= +##contig= +##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta +##readme=AAAAAA +##readme=BBBBBB +##INFO= +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 2:A 2:B +1 3000000 . C G 59.2 PASS AN=4;AC=2 GT:GQ ./.:. ./.:. 0/1:245 0/1:245 +1 3000000 . C CCG 59.2 PASS AN=4;AC=2 GT:GQ 0/1:245 0/1:245 ./.:. ./.:. +1 3000150 . C A,G 59.2 PASS AN=8;AC=2,2 GT:GQ 0/1:245 0/1:245 0/2:245 0/2:245 +1 3000151 . C A,G 59.2 PASS AN=8;AC=2,2 GT:DP:GQ 0/1:32:245 0/1:32:245 0/2:32:245 0/2:32:245 +1 3106154 . C A,T 59.2 PASS AN=8;AC=2,2 GT:GQ:DP 0/1:245:32 0/1:245:32 0/2:245:32 0/2:245:32 +1 3106154 . C CC,CCC 342 PASS AN=8;AC=2,2 GT:GQ:DP 0/1:245:32 0/1:245:32 0/2:245:32 0/2:245:32 +1 3200000 . C T 59.2 PASS AN=8;AC=4 GT:GQ:DP 0/1:245:32 0/1:245:32 0/1:245:32 0/1:245:32 +1 3200010 . C T,A 59.2 PASS AN=8;AC=2,2 GT:GQ:DP 0/1:245:32 0/1:245:32 0/2:245:32 0/2:245:32 +1 3200020 . C G,T 59.2 PASS AN=0;AC=0,0 GT:GL ./.:1,2,3,4,5,6 .:1,2,3 ./.:1,2,3,4,5,6 .:1,2,3 diff --git a/test/merge.2.none.out b/test/merge.2.none.out new file mode 100644 index 0000000..fe1a7a7 --- /dev/null +++ b/test/merge.2.none.out @@ -0,0 +1,36 @@ +##fileformat=VCFv4.1 +##FILTER= +##INFO= +##FORMAT= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FILTER= +##FILTER= +##contig= +##contig= +##contig= +##contig= +##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta +##readme=AAAAAA +##readme=BBBBBB +##INFO= +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 2:A 2:B +1 3000000 . C G 59.2 PASS AN=4;AC=2 GT:GQ ./.:. ./.:. 0/1:245 0/1:245 +1 3000000 . C CCG 59.2 PASS AN=4;AC=2 GT:GQ 0/1:245 0/1:245 ./.:. ./.:. +1 3000150 . C A 59.2 PASS AN=4;AC=2 GT:GQ 0/1:245 0/1:245 ./.:. ./.:. +1 3000150 . C G 59.2 PASS AN=4;AC=2 GT:GQ ./.:. ./.:. 0/1:245 0/1:245 +1 3000151 . C A 59.2 PASS AN=4;AC=2 GT:DP:GQ 0/1:32:245 0/1:32:245 ./.:.:. ./.:.:. +1 3000151 . C G 59.2 PASS AN=4;AC=2 GT:DP:GQ ./.:.:. ./.:.:. 0/1:32:245 0/1:32:245 +1 3106154 . C A 59.2 PASS AN=4;AC=2 GT:GQ:DP 0/1:245:32 0/1:245:32 ./.:.:. ./.:.:. +1 3106154 . C T 59.2 PASS AN=4;AC=2 GT:GQ:DP ./.:.:. ./.:.:. 0/1:245:32 0/1:245:32 +1 3106154 . C CC 342 PASS AN=4;AC=2 GT:GQ:DP 0/1:245:32 0/1:245:32 ./.:.:. ./.:.:. +1 3106154 . C CCC 342 PASS AN=4;AC=2 GT:GQ:DP ./.:.:. ./.:.:. 0/1:245:32 0/1:245:32 +1 3200000 . C T 59.2 PASS AN=8;AC=4 GT:GQ:DP 0/1:245:32 0/1:245:32 0/1:245:32 0/1:245:32 +1 3200010 . C T,A 59.2 PASS AN=8;AC=2,2 GT:GQ:DP 0/1:245:32 0/1:245:32 0/2:245:32 0/2:245:32 +1 3200020 . C G,T 59.2 PASS AN=0;AC=0,0 GT:GL ./.:1,2,3,4,5,6 .:1,2,3 ./.:1,2,3,4,5,6 .:1,2,3 diff --git a/test/merge.3.a.vcf b/test/merge.3.a.vcf new file mode 100644 index 0000000..2f2af22 --- /dev/null +++ b/test/merge.3.a.vcf @@ -0,0 +1,26 @@ +##fileformat=VCFv4.1 +##INFO= +##FORMAT= +##INFO= +##INFO= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FILTER= +##FILTER= +##contig= +##contig= +##contig= +##contig= +##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta +##readme=AAAAAA +##readme=BBBBBB +##INFO= +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B +1 3000000 . C CCG 59.2 PASS AN=4;AC=2;TR=1,2;TA=1;TG=1,2,3 GT:GQ 0/1:245 0/1:245 diff --git a/test/merge.3.b.vcf b/test/merge.3.b.vcf new file mode 100644 index 0000000..05c2385 --- /dev/null +++ b/test/merge.3.b.vcf @@ -0,0 +1,26 @@ +##fileformat=VCFv4.1 +##INFO= +##FORMAT= +##INFO= +##INFO= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FILTER= +##FILTER= +##contig= +##contig= +##contig= +##contig= +##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta +##readme=AAAAAA +##readme=BBBBBB +##INFO= +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B +1 3000000 . C CG 59.2 PASS AN=4;AC=2;TR=10,20;TA=10;TG=10,20,30 GT:GQ 0/1:245 0/1:245 diff --git a/test/merge.3.out b/test/merge.3.out new file mode 100644 index 0000000..bcb9f2f --- /dev/null +++ b/test/merge.3.out @@ -0,0 +1,27 @@ +##fileformat=VCFv4.1 +##FILTER= +##INFO= +##FORMAT= +##INFO= +##INFO= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FILTER= +##FILTER= +##contig= +##contig= +##contig= +##contig= +##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta +##readme=AAAAAA +##readme=BBBBBB +##INFO= +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 2:A 2:B +1 3000000 . 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C CCG 59.2 PASS AN=4;AC=2 GT:GQ 0/1:245 0/1:245 +1 3000002 id2 C CCG 59.2 PASS AN=4;AC=2;TR=1,2;TA=1;TG=1,2,3 GT:GL:XR:XA:XG 0/1:245:.:.:. 0/1:245:.:.:. +1 3000002 id3 C CCG 59.2 PASS AN=4;AC=2;TR=1,2;TA=1;TG=1,2,3 GT:GL:XR:XA:XG 0/1:245:.:.:. 0/1:245:. diff --git a/test/merge.4.b.vcf b/test/merge.4.b.vcf new file mode 100644 index 0000000..461661b --- /dev/null +++ b/test/merge.4.b.vcf @@ -0,0 +1,33 @@ +##fileformat=VCFv4.1 +##INFO= +##FORMAT= +##INFO= +##INFO= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FILTER= +##FILTER= +##contig= +##contig= +##contig= +##contig= +##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta +##readme=AAAAAA +##readme=BBBBBB +##INFO= +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT C D +1 3000000 . C A 59.2 PASS AN=4;AC=2 GT:GQ 0/1:245 0/1:245 +1 3000000 id1 C A 59.2 PASS AN=4;AC=2;TR=1,2;TA=1;TG=1,2,3 GT:GQ:XR:XG:XA 0/1:245:4,5:3,4,5:5 0/1:245:6,7:6,7,8:7 +1 3000002 id3 C A 59.2 PASS AN=4;AC=2;TR=1,2;TA=1;TG=1,2,3 GT:GQ:XR:XG:XA 0/1:245:. 0/1:245:1,2:1,2,3:2 +1 3000002 id2 C A 59.2 PASS AN=4;AC=2;TR=1,2;TA=1;TG=1,2,3 GT:GQ:XR:XG:XA 0/1:245:. 0/1:245:.:.:. +1 3000002 . C A 59.2 PASS AN=4;AC=2 GT:GQ 0/1:245 0/1:245 diff --git a/test/merge.4.out b/test/merge.4.out new file mode 100644 index 0000000..8b69f2b --- /dev/null +++ b/test/merge.4.out @@ -0,0 +1,34 @@ +##fileformat=VCFv4.1 +##FILTER= +##INFO= +##FORMAT= +##INFO= +##INFO= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FILTER= +##FILTER= +##contig= +##contig= +##contig= +##contig= +##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta +##readme=AAAAAA +##readme=BBBBBB +##INFO= +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B C D +1 3000000 id1 C CCG,A 59.2 PASS TR=1,2,2;TA=1,1;TG=1,2,3,2,.,3;AN=8;AC=2,2 GT:GQ:XR:XA:XG 0/1:245:0,1,.:1,.:0,1,2,.,.,. 0/1:245:1,2,.:2,.:0,1,2,.,.,. 0/2:245:4,.,5:.,5:3,.,.,4,.,5 0/2:245:6,.,7:.,7:6,.,.,7,.,8 +1 3000000 . C CCG,A 59.2 PASS AN=8;AC=2,2 GT:GQ:XR:XA:XG 0/1:245:1,2,.:2,.:0,1,2,.,.,. 0/1:245:2,3,.:3,.:1,2,3,.,.,. 0/2:245:.:.:. 0/2:245:.:.:. +1 3000002 . C CCG,A 59.2 PASS AN=8;AC=2,2 GT:GQ 0/1:245 0/1:245 0/2:245 0/2:245 +1 3000002 id2 C CCG,A 59.2 PASS TR=1,2,2;TA=1,1;TG=1,2,3,2,.,3;AN=8;AC=2,2 GT:GL:XR:XA:XG:GQ 0/1:245,245,-1.56481e-39,.,.,.:.:.:.:. 0/1:245,-1.56481e-39,1.09706e-28,.,.,.:.:.:.:. 0/2:.:.:.:.:245 0/2:.:.:.:.:245 +1 3000002 id3 C CCG,A 59.2 PASS TR=1,2,2;TA=1,1;TG=1,2,3,2,.,3;AN=8;AC=2,2 GT:GL:XR:XA:XG:GQ 0/1:245,245,-1.56481e-39,.,.,.:.:.:.:. 0/1:245,-1.56481e-39,1.09706e-28,.,.,.:.:.:.:. 0/2:.:.:.:.:245 0/2:.:1,.,2:.,2:1,.,.,2,.,3:245 diff --git a/test/merge.5.a.vcf b/test/merge.5.a.vcf new file mode 100644 index 0000000..011a681 --- /dev/null +++ b/test/merge.5.a.vcf @@ -0,0 +1,8 @@ +##fileformat=VCFv4.2 +##FORMAT= +##contig= +##reference=file:///home/dnanexus/genome.fa +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT t1 +1 11080563 . AACACAC A,AAC 4321.7 . . GT 0/2 +1 11080564 . ACACAC AACAC,* 5809.43 . . GT 0/1 +1 11080566 . ACACAC A,AAC,* 5215.77 . . GT 0/2 diff --git a/test/merge.5.b.vcf b/test/merge.5.b.vcf new file mode 100644 index 0000000..1da10e8 --- /dev/null +++ b/test/merge.5.b.vcf @@ -0,0 +1,7 @@ +##fileformat=VCFv4.2 +##FORMAT= +##contig= +##reference=file:///home/dnanexus/genome.fa +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT t2 +1 11080564 . ACACACAC AACACAC,* 6150.42 . . GT 0/1 +1 11080566 . ACACAC A,AAC,* 5296.77 . . GT 0/2 diff --git a/test/merge.5.out b/test/merge.5.out new file mode 100644 index 0000000..6226b4b --- /dev/null +++ b/test/merge.5.out @@ -0,0 +1,9 @@ +##fileformat=VCFv4.2 +##FILTER= +##FORMAT= +##contig= +##reference=file:///home/dnanexus/genome.fa +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT t1 t2 +1 11080563 . AACACAC A,AAC 4321.7 . . GT 0/2 ./. +1 11080564 . ACACACAC AACACAC,* 6150.42 . . GT 0/1 0/1 +1 11080566 . ACACAC A,AAC,* 5296.77 . . GT 0/2 0/2 diff --git a/test/merge.a.chk b/test/merge.a.chk new file mode 100644 index 0000000..e88112d --- /dev/null +++ b/test/merge.a.chk @@ -0,0 +1,58 @@ +# This file was produced by vcfcheck and can be plotted using plot-vcfcheck. +# +# Definition of sets: +# ID [2]id [3]tab-separated file names +# SN, Summary numbers: +# SN [2]id [3]key [4]value +SN 0 number of samples: 2 +SN 0 number of SNPs: 1 +SN 0 number of MNPs: 0 +SN 0 number of indels: 10 +SN 0 number of others: 0 +SN 0 number of multiallelic sites: 4 +SN 0 ts/tv: 0.00 +# Sis, Singleton stats: +# SiS [2]id [3]allele count [4]number of SNPs [5]number of transitions [6]number of transversions [7]number of indels +SiS 0 1 2 0 2 0 +# AF, Stats by non-reference allele frequency: +# AF [2]id [3]allele frequency [4]number of SNPs [5]number of transitions [6]number of transversions [7]number of indels +AF 0 0.000000 2 0 2 0 +AF 0 49.494949 0 0 0 12 +AF 0 100.000000 0 0 0 1 +# IDD, InDel distribution: +# IDD [2]id [3]length (deletions negative) [4]count +IDD 0 -8 1 +IDD 0 -4 1 +IDD 0 -3 3 +IDD 0 -2 2 +IDD 0 -1 3 +IDD 0 1 2 +IDD 0 2 1 +# ST, Substitution types: +# ST [2]id [3]type [4]count +ST 0 A>C 0 +ST 0 A>G 0 +ST 0 A>T 0 +ST 0 C>A 0 +ST 0 C>G 0 +ST 0 C>T 0 +ST 0 G>A 0 +ST 0 G>C 1 +ST 0 G>T 1 +ST 0 T>A 0 +ST 0 T>C 0 +ST 0 T>G 0 +# PSC, Per-sample counts +# PSC [2]id [3]sample [4]nRefHom [5]nNonRefHom [6]nHets [7]nTransitions [8]nTransversions [9]nIndels [10]average depth +PSC 0 A 0 0 1 0 1 10 27 +PSC 0 B 0 0 1 0 1 10 27 +# DP, Depth distribution +# DP [2]id [3]bin [4]number of genotypes [5]fraction of genotypes (%) +DP 0 10 2 9.090909 +DP 0 21 2 9.090909 +DP 0 22 2 9.090909 +DP 0 26 4 18.181818 +DP 0 30 2 9.090909 +DP 0 31 2 9.090909 +DP 0 32 4 18.181818 +DP 0 35 4 18.181818 diff --git a/test/merge.a.vcf b/test/merge.a.vcf new file mode 100644 index 0000000..02923ae --- /dev/null +++ b/test/merge.a.vcf @@ -0,0 +1,36 @@ +##fileformat=VCFv4.1 +##INFO= +##FORMAT= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FILTER= +##FILTER= +##contig= +##contig= +##contig= +##contig= +##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta +##readme=AAAAAA +##readme=BBBBBB +##INFO= +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B +1 3000150 . C T 59.2 PASS AN=4;AC=2 GT:GQ 0/1:245 0/1:245 +1 3000151 . C T 59.2 PASS AN=4;AC=2 GT:DP:GQ 0/1:32:245 0/1:32:245 +1 3062915 id3D GTTT G 12.9 q10 DP4=1,2,3,4;AN=4;AC=2;INDEL;STR=test GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 0/1:409:35:-20,-5,-20 +1 3062915 idSNP G T,C 12.6 test TEST=5;DP4=1,2,3,4;AN=3;AC=1,1 GT:TT:GQ:DP:GL 0/1:0,1:409:35:-20,-5,-20,-20,-5,-20 2:0,1:409:35:-20,-5,-20 +1 3106154 . CAAA C 342 PASS AN=4;AC=2 GT:GQ:DP 0/1:245:32 0/1:245:32 +1 3106154 . C CT 59.2 PASS AN=4;AC=2 GT:GQ:DP 0/1:245:32 0/1:245:32 +1 3157410 . GA G 90.6 q10 AN=4;AC=4 GT:GQ:DP 1/1:21:21 1/1:21:21 +1 3162006 . GAA G 60.2 PASS AN=4;AC=2 GT:GQ:DP 0/1:212:22 0/1:212:22 +1 3177144 . G T 45 PASS AN=4;AC=2 GT:GQ:DP 0/0:150:30 1/1:150:30 +1 3177144 . G . 45 PASS AN=4;AC=0 GT:GQ:DP 0/0:150:30 0/0:150:30 +1 3184885 . TAAAA TA,T 61.5 PASS AN=4;AC=2,2 GT:GQ:DP 1/2:12:10 1/2:12:10 +2 3199812 . G GTT,GT 82.7 PASS AN=4;AC=2,2 GT:GQ:DP 1/2:322:26 1/2:322:26 +3 3212016 . CTT C,CT 79 PASS AN=4;AC=2,2 GT:GQ:DP 1/2:91:26 1/2:91:26 +4 3258448 . TACACACAC T . PASS AN=4;AC=2 GT:GQ:DP 0/1:325:31 0/1:325:31 diff --git a/test/merge.abc.2.out b/test/merge.abc.2.out new file mode 100644 index 0000000..8e3ebe8 --- /dev/null +++ b/test/merge.abc.2.out @@ -0,0 +1,58 @@ +##fileformat=VCFv4.1 +##FILTER= +##INFO= +##FORMAT= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FILTER= +##FILTER= +##contig= +##contig= +##contig= +##contig= +##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta +##readme=AAAAAA +##readme=BBBBBB +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##SAMPLE=\") quoting nonsense where double brackets would do just fine",softwareName=,softwareVer=<119,65>,softwareParam=<.>,MetadataResource=http://somewhere.com/path> +##FORMAT= +##FILTER= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 2:B C D +1 3000150 . C T 59.2 PASS AN=4;AC=2 GT:GQ 0/1:245 0/1:245 ./.:. ./.:. ./.:. +1 3000151 . C T 59.2 PASS AN=4;AC=2 GT:DP:GQ 0/1:32:245 0/1:32:245 ./.:.:. ./.:.:. ./.:.:. +1 3062915 idSNP G T,C,A 419 test;q20 TEST=5;STR=.;DP=14;DP4=3,6,9,12;INTA=2,1,.;AN=9;AC=2,2,1 GT:TT:GQ:DP:GL:STR 0/1:0,1,.:409:35:-20,-5,-20,-20,-5,-20,.,.,.,.:. 2:0,1,.:409:35:-20,-5,-20,.:. 0/3:.:376:14:-10,.,.,.,.,.,0,.,.,-10:ABC 0/2:1,0,.:409:35:-20,-20,-20,-5,-5,-20,.,.,.,.:. 0/1:1,0,.:409:35:-20,-20,-20,-5,-5,-20,.,.,.,.:. +1 3062915 id3D GTTT G 84.6 q10;q20 INDEL;STR=test;TXT=AA;DP=1013;DP4=6,7,8,9;AN=10;AC=5 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 0/1:409:35:-20,-5,-20 0/1:376:14:-10,0,-10 0/1:409:35:-20,-5,-20 0/1:409:35:-20,-5,-20 +1 3062915 id1D;id2D GTT GT,G 999 q20;q10 DP=14;DP4=2,4,6,8;AN=6;AC=1,2 GT:GQ:DP:GL:STR ./.:.:.:.:. ./.:.:.:.:. 0/1:376:14:-10,0,-10,.,.,.:DEF 0/2:409:35:-20,.,.,-5,.,-20:. 0/2:409:35:-20,.,.,-5,.,-20:. +1 3106154 . C T 999 PASS DP=15;AN=2;AC=1 GT:GQ:DP:GL ./.:.:.:. ./.:.:.:. 0/1:277:15:-10,0,-10 ./.:.:.:. ./.:.:.:. +1 3106154 . CAAAA CA,C 342 PASS DP=15;AN=6;AC=2,1 GT:GQ:DP:GL 0/1:245:32:. 0/1:245:32:. 0/2:277:15:-10,.,.,0,.,-10 .:245:32:. ./.:245:32:. +1 3106154 . C CT 459 PASS AN=8;AC=4 GT:GQ:DP 0/1:245:32 0/1:245:32 ./.:.:. 0/1:245:32 0/1:245:32 +1 3157410 . G T 46.7 q10 AN=4;AC=4 GT:GQ:DP ./.:.:. ./.:.:. ./.:.:. 1/1:21:21 1/1:21:21 +1 3157410 . GAC GC,G 90.6 PASS DP=11;AN=6;AC=4,1 GT:GQ:DP 1/1:21:21 1/1:21:21 0/2:49:11 ./.:.:. ./.:.:. +1 3162006 . GAA G,GA 238 PASS DP=19;XRF=1e+06,2e+06,500000;XRI=1111,2222,5555;XRS=AAA,BBB,DDD;XAF=1e+06,500000;XAI=1111,5555;XAS=AAA,DDD;XGF=1e+06,2e+06,3e+06,500000,.,9e+09;XGI=1111,2222,3333,5555,.,9999;XGS=A,B,C,E,.,F;AN=10;AC=3,2 GT:GQ:DP 0/1:212:22 0/1:212:22 0/1:589:19 0/2:212:22 0/2:212:22 +1 3177144 . G T 999 PASS DP=24;AN=10;AC=3 GT:GQ:DP 0/0:150:30 1/1:150:30 0/1:236:24 0/0:150:30 0/0:150:30 +1 3177144 . GT G 999 PASS DP=24;AN=6;AC=1 GT:GQ:DP 0/0:150:30 0/0:150:30 0/1:236:24 ./.:.:. ./.:.:. +1 3184885 . TAAAA TA,T 61.5 PASS DP=16;AN=10;AC=5,4 GT:GQ:DP 1/2:12:10 1/2:12:10 0/1:435:16 1/2:12:10 1/2:12:10 +2 3188209 . GA G 41.5 PASS DP=15;AN=2;AC=1 GT:GQ:DP ./.:.:. ./.:.:. 0/1:162:15 ./.:.:. ./.:.:. +2 3199812 . G GTT,GT 291 PASS AN=8;AC=4,4 GT:GQ:DP 1/2:322:26 1/2:322:26 ./.:.:. 1/2:322:26 1/2:322:26 +3 3199812 . GA GTT,GT 17.5 PASS DP=19;AN=2;AC=1,1 GT:GQ:DP ./.:.:. ./.:.:. 1/2:188:19 ./.:.:. ./.:.:. +3 3212016 . CTT C,CT 79 PASS AN=8;AC=4,4 GT:GQ:DP 1/2:91:26 1/2:91:26 ./.:.:. 1/2:91:26 1/2:91:26 +4 3212016 . CTT C 999 q20 DP=15;AN=2;AC=1 GT:GQ:DP ./.:.:. ./.:.:. 0/1:158:15 ./.:.:. ./.:.:. +4 3258448 . TACACACAC T . PASS AN=8;AC=4 GT:GQ:DP 0/1:325:31 0/1:325:31 ./.:.:. 0/1:325:31 0/1:325:31 diff --git a/test/merge.abc.3.out b/test/merge.abc.3.out new file mode 100644 index 0000000..3f073f7 --- /dev/null +++ b/test/merge.abc.3.out @@ -0,0 +1,58 @@ +##fileformat=VCFv4.1 +##FILTER= +##INFO= +##FORMAT= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FILTER= +##FILTER= +##contig= +##contig= +##contig= +##contig= +##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta +##readme=AAAAAA +##readme=BBBBBB +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##SAMPLE=\") quoting nonsense where double brackets would do just fine",softwareName=,softwareVer=<119,65>,softwareParam=<.>,MetadataResource=http://somewhere.com/path> +##FORMAT= +##FILTER= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 2:B C D +1 3000150 . C T 59.2 PASS AN=10;AC=2 GT:GQ 0/1:245 0/1:245 0/0:. 0/0:. 0/0:. +1 3000151 . C T 59.2 PASS AN=10;AC=2 GT:DP:GQ 0/1:32:245 0/1:32:245 0/0:.:. 0/0:.:. 0/0:.:. +1 3062915 idSNP G T,C,A 419 test;q20 TEST=5;STR=.;DP=14;DP4=3,6,9,12;INTA=2,1,.;AN=9;AC=2,2,1 GT:TT:GQ:DP:GL:STR 0/1:0,1,.:409:35:-20,-5,-20,-20,-5,-20,.,.,.,.:. 2:0,1,.:409:35:-20,-5,-20,.:. 0/3:.:376:14:-10,.,.,.,.,.,0,.,.,-10:ABC 0/2:1,0,.:409:35:-20,-20,-20,-5,-5,-20,.,.,.,.:. 0/1:1,0,.:409:35:-20,-20,-20,-5,-5,-20,.,.,.,.:. +1 3062915 id3D GTTT G 84.6 q10;q20 INDEL;STR=test;TXT=AA;DP=1013;DP4=6,7,8,9;AN=10;AC=5 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 0/1:409:35:-20,-5,-20 0/1:376:14:-10,0,-10 0/1:409:35:-20,-5,-20 0/1:409:35:-20,-5,-20 +1 3062915 id1D;id2D GTT GT,G 999 q20;q10 DP=14;DP4=2,4,6,8;AN=10;AC=1,2 GT:GQ:DP:GL:STR 0/0:.:.:.:. 0/0:.:.:.:. 0/1:376:14:-10,0,-10,.,.,.:DEF 0/2:409:35:-20,.,.,-5,.,-20:. 0/2:409:35:-20,.,.,-5,.,-20:. +1 3106154 . C T 999 PASS DP=15;AN=10;AC=1 GT:GQ:DP:GL 0/0:.:.:. 0/0:.:.:. 0/1:277:15:-10,0,-10 0/0:.:.:. 0/0:.:.:. +1 3106154 . CAAAA CA,C 342 PASS DP=15;AN=6;AC=2,1 GT:GQ:DP:GL 0/1:245:32:. 0/1:245:32:. 0/2:277:15:-10,.,.,0,.,-10 .:245:32:. ./.:245:32:. +1 3106154 . C CT 459 PASS AN=10;AC=4 GT:GQ:DP 0/1:245:32 0/1:245:32 0/0:.:. 0/1:245:32 0/1:245:32 +1 3157410 . G T 46.7 q10 AN=10;AC=4 GT:GQ:DP 0/0:.:. 0/0:.:. 0/0:.:. 1/1:21:21 1/1:21:21 +1 3157410 . GAC GC,G 90.6 q10 DP=11;AN=10;AC=4,1 GT:GQ:DP 1/1:21:21 1/1:21:21 0/2:49:11 0/0:.:. 0/0:.:. +1 3162006 . GAA G,GA 238 PASS DP=19;XRF=1e+06,2e+06,500000;XRI=1111,2222,5555;XRS=AAA,BBB,DDD;XAF=1e+06,500000;XAI=1111,5555;XAS=AAA,DDD;XGF=1e+06,2e+06,3e+06,500000,.,9e+09;XGI=1111,2222,3333,5555,.,9999;XGS=A,B,C,E,.,F;AN=10;AC=3,2 GT:GQ:DP 0/1:212:22 0/1:212:22 0/1:589:19 0/2:212:22 0/2:212:22 +1 3177144 . G T 999 PASS DP=24;AN=10;AC=3 GT:GQ:DP 0/0:150:30 1/1:150:30 0/1:236:24 0/0:150:30 0/0:150:30 +1 3177144 . GT G 999 PASS DP=24;AN=10;AC=1 GT:GQ:DP 0/0:150:30 0/0:150:30 0/1:236:24 0/0:.:. 0/0:.:. +1 3184885 . TAAAA TA,T 61.5 PASS DP=16;AN=10;AC=5,4 GT:GQ:DP 1/2:12:10 1/2:12:10 0/1:435:16 1/2:12:10 1/2:12:10 +2 3188209 . GA G 41.5 . DP=15;AN=10;AC=1 GT:GQ:DP 0/0:.:. 0/0:.:. 0/1:162:15 0/0:.:. 0/0:.:. +2 3199812 . G GTT,GT 291 PASS AN=10;AC=4,4 GT:GQ:DP 1/2:322:26 1/2:322:26 0/0:.:. 1/2:322:26 1/2:322:26 +3 3199812 . GA GTT,GT 17.5 PASS DP=19;AN=10;AC=1,1 GT:GQ:DP 0/0:.:. 0/0:.:. 1/2:188:19 0/0:.:. 0/0:.:. +3 3212016 . CTT C,CT 79 PASS AN=10;AC=4,4 GT:GQ:DP 1/2:91:26 1/2:91:26 0/0:.:. 1/2:91:26 1/2:91:26 +4 3212016 . CTT C 999 q20 DP=15;AN=10;AC=1 GT:GQ:DP 0/0:.:. 0/0:.:. 0/1:158:15 0/0:.:. 0/0:.:. +4 3258448 . TACACACAC T . PASS AN=10;AC=4 GT:GQ:DP 0/1:325:31 0/1:325:31 0/0:.:. 0/1:325:31 0/1:325:31 diff --git a/test/merge.abc.out b/test/merge.abc.out new file mode 100644 index 0000000..143bf62 --- /dev/null +++ b/test/merge.abc.out @@ -0,0 +1,58 @@ +##fileformat=VCFv4.1 +##FILTER= +##INFO= +##FORMAT= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FILTER= +##FILTER= +##contig= +##contig= +##contig= +##contig= +##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta +##readme=AAAAAA +##readme=BBBBBB +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##SAMPLE=\") quoting nonsense where double brackets would do just fine",softwareName=,softwareVer=<119,65>,softwareParam=<.>,MetadataResource=http://somewhere.com/path> +##FORMAT= +##FILTER= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B 2:B C D +1 3000150 . C T 59.2 PASS AN=4;AC=2 GT:GQ 0/1:245 0/1:245 ./.:. ./.:. ./.:. +1 3000151 . C T 59.2 PASS AN=4;AC=2 GT:DP:GQ 0/1:32:245 0/1:32:245 ./.:.:. ./.:.:. ./.:.:. +1 3062915 idSNP G T,C,A 419 test;q20 TEST=5;STR=.;DP=14;DP4=3,6,9,12;INTA=2,1,.;AN=9;AC=2,2,1 GT:TT:GQ:DP:GL:STR 0/1:0,1,.:409:35:-20,-5,-20,-20,-5,-20,.,.,.,.:. 2:0,1,.:409:35:-20,-5,-20,.:. 0/3:.:376:14:-10,.,.,.,.,.,0,.,.,-10:ABC 0/2:1,0,.:409:35:-20,-20,-20,-5,-5,-20,.,.,.,.:. 0/1:1,0,.:409:35:-20,-20,-20,-5,-5,-20,.,.,.,.:. +1 3062915 id3D GTTT G 84.6 q10;q20 INDEL;STR=test;TXT=AA;DP=1013;DP4=6,7,8,9;AN=10;AC=5 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 0/1:409:35:-20,-5,-20 0/1:376:14:-10,0,-10 0/1:409:35:-20,-5,-20 0/1:409:35:-20,-5,-20 +1 3062915 id1D;id2D GTT GT,G 999 q20;q10 DP=14;DP4=2,4,6,8;AN=6;AC=1,2 GT:GQ:DP:GL:STR ./.:.:.:.:. ./.:.:.:.:. 0/1:376:14:-10,0,-10,.,.,.:DEF 0/2:409:35:-20,.,.,-5,.,-20:. 0/2:409:35:-20,.,.,-5,.,-20:. +1 3106154 . C T 999 PASS DP=15;AN=2;AC=1 GT:GQ:DP:GL ./.:.:.:. ./.:.:.:. 0/1:277:15:-10,0,-10 ./.:.:.:. ./.:.:.:. +1 3106154 . CAAAA CA,C 342 PASS DP=15;AN=6;AC=2,1 GT:GQ:DP:GL 0/1:245:32:. 0/1:245:32:. 0/2:277:15:-10,.,.,0,.,-10 .:245:32:. ./.:245:32:. +1 3106154 . C CT 459 PASS AN=8;AC=4 GT:GQ:DP 0/1:245:32 0/1:245:32 ./.:.:. 0/1:245:32 0/1:245:32 +1 3157410 . G T 46.7 q10 AN=4;AC=4 GT:GQ:DP ./.:.:. ./.:.:. ./.:.:. 1/1:21:21 1/1:21:21 +1 3157410 . GAC GC,G 90.6 q10 DP=11;AN=6;AC=4,1 GT:GQ:DP 1/1:21:21 1/1:21:21 0/2:49:11 ./.:.:. ./.:.:. +1 3162006 . GAA G,GA 238 PASS DP=19;XRF=1e+06,2e+06,500000;XRI=1111,2222,5555;XRS=AAA,BBB,DDD;XAF=1e+06,500000;XAI=1111,5555;XAS=AAA,DDD;XGF=1e+06,2e+06,3e+06,500000,.,9e+09;XGI=1111,2222,3333,5555,.,9999;XGS=A,B,C,E,.,F;AN=10;AC=3,2 GT:GQ:DP 0/1:212:22 0/1:212:22 0/1:589:19 0/2:212:22 0/2:212:22 +1 3177144 . G T 999 PASS DP=24;AN=10;AC=3 GT:GQ:DP 0/0:150:30 1/1:150:30 0/1:236:24 0/0:150:30 0/0:150:30 +1 3177144 . 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GT:DP:GQ 0/0:32:245 0/0:32:245 +1 3062915 id3D GTTT G 12.9 q10 DP4=1,2,3,4;INDEL;STR=test GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 0/1:409:35:-20,-5,-20 +1 3062915 idSNP G T,C 12.6 test TEST=5;DP4=1,2,3,4 GT:TT:GQ:DP:GL 0/1:0,1:409:35:-20,-5,-20,-20,-5,-20 2:0,1:409:35:-20,-5,-20 +1 3106154 . CAAA C 342 PASS . GT:GQ:DP 0/0:245:32 0/0:245:32 +1 3106154 . C CT 59.2 PASS . GT:GQ:DP 0/0:245:32 0/0:245:32 +1 3157410 . GA G 90.6 q10 . GT:GQ:DP 1/1:21:21 1/1:21:21 +1 3162006 . GAA G 60.2 PASS . GT:GQ:DP 0/0:212:22 0/0:212:22 +1 3177144 . G T 45 PASS . GT:GQ:DP 0/0:150:30 0/0:150:30 +1 3177144 . G . 45 PASS . GT:GQ:DP 0/0:150:30 0/0:150:30 +1 3184885 . TAAAA TA,T 61.5 PASS . GT:GQ:DP 0/0:12:10 0/0:12:10 +2 3199812 . G GTT,GT 82.7 PASS . GT:GQ:DP 0/0:322:26 0/0:322:26 +3 3212016 . CTT C,CT 79 PASS . GT:GQ:DP 0/0:91:26 0/0:91:26 +4 3258448 . TACACACAC T 59.9 PASS . 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DP=25;VDB=0.842082;SGB=-4.20907;RPB=0.950652;MQB=1;MQSB=1;BQB=0.929717;MQ0F=0;ICB=0.8;HOB=0.222222;AC=4;AN=6;DP4=2,4,8,11;MQ=60 GT:PL:DP:DV 0/1:211,0,35:12:10 0/1:116,0,91:9:5 1/1:120,12,0:4:4 +17 834 . G A 364 . DP=25;VDB=0.788006;SGB=-4.01214;RPB=0.999233;MQB=1;MQSB=1;BQB=0.821668;MQ0F=0;ICB=0.8;HOB=0.222222;AC=4;AN=6;DP4=2,3,7,10;MQ=60 GT:PL:DP:DV 0/1:185,0,46:11:9 0/1:128,0,59:8:5 1/1:89,9,0:3:3 +17 1665 . T C 3.10665 . DP=20;VDB=0.1;SGB=0.346553;RPB=0.222222;MQB=0.611111;MQSB=0.988166;BQB=0.944444;MQ0F=0;ICB=0.128205;HOB=0.0555556;AC=1;AN=6;DP4=7,11,1,1;MQ=55 GT:PL:DP:DV 0/0:0,21,185:7:0 0/0:0,27,222:9:0 0/1:35,0,51:4:2 +17 1869 . A T 138 . DP=24;VDB=0.928022;SGB=-11.9537;RPB=0.984127;MQB=0.96464;MQSB=0.931547;BQB=0.359155;MQ0F=0;ICB=0.8;HOB=0.222222;AC=4;AN=6;DP4=6,9,5,4;MQ=58 GT:PL:DP:DV 0/1:115,0,224:18:7 0/1:16,0,104:5:1 1/1:42,3,0:1:1 +17 2041 . G A 447 . DP=31;VDB=0.816435;SGB=-4.18892;RPB=0.88473;MQB=0.972375;MQSB=0.968257;BQB=0.311275;MQ0F=0;ICB=0.8;HOB=0.222222;AC=4;AN=6;DP4=6,5,12,7;MQ=58 GT:PL:DP:DV 0/1:229,0,212:21:11 0/1:32,0,24:2:1 1/1:223,21,0:7:7 +17 2220 . G A 303 . DP=21;VDB=0.532753;SGB=-3.51597;RPB=0.964198;MQB=0.898397;MQSB=0.875769;BQB=0.0354359;MQ0F=0;ICB=0.8;HOB=0.222222;AC=4;AN=6;DP4=6,2,1,11;MQ=58 GT:PL:DP:DV 0/1:139,0,130:12:6 0/1:69,0,46:4:2 1/1:131,12,0:4:4 +17 2564 . A G 233 . DP=15;VDB=0.690812;SGB=-3.20711;RPB=0.197899;MQB=1;MQSB=1;BQB=0.965069;MQ0F=0;ICB=0.8;HOB=0.222222;AC=4;AN=6;DP4=1,4,4,5;MQ=60 GT:PL:DP:DV 0/1:88,0,78:6:3 0/1:57,0,56:4:2 1/1:124,12,0:4:4 +17 3104 . C T 24.2837 . DP=25;VDB=0.8;SGB=0.346553;RPB=0.717391;MQB=0.956522;MQSB=0.962269;BQB=0.978261;MQ0F=0;ICB=0.128205;HOB=0.0555556;AC=1;AN=6;DP4=8,15,2,0;MQ=58 GT:PL:DP:DV 0/0:0,48,255:16:0 0/0:0,12,144:4:0 0/1:59,0,93:5:2 +17 3587 . G A 358 . DP=29;VDB=0.902044;SGB=-3.91326;RPB=0.800999;MQB=1;MQSB=1;BQB=0.156944;MQ0F=0;ICB=0.8;HOB=0.222222;AC=4;AN=6;DP4=4,7,10,6;MQ=60 GT:PL:DP:DV 0/1:161,0,184:14:7 0/1:22,0,118:5:1 1/1:212,24,0:8:8 +17 3936 . A G 469 . DP=37;VDB=0.0574114;SGB=-4.60123;RPB=0.741697;MQB=0.812605;MQSB=0.143788;BQB=0.883831;MQ0F=0;ICB=0.8;HOB=0.222222;AC=4;AN=6;DP4=5,6,6,17;MQ=56 GT:PL:DP:DV 0/1:233,0,206:20:11 0/1:77,0,58:6:4 1/1:196,24,0:8:8 diff --git a/test/mpileup.2.out b/test/mpileup.2.out new file mode 100644 index 0000000..d657160 --- /dev/null +++ b/test/mpileup.2.out @@ -0,0 +1,54 @@ +##fileformat=VCFv4.2 +##FILTER= +##samtoolsVersion=1.1-19-g6b249e2+htslib-1.1-74-g845c515 +##samtoolsCommand=samtools mpileup -uvDV -b xxx//mpileup.bam.list -f xxx//mpileup.ref.fa.gz +##reference=file://xxx//mpileup.ref.fa.gz +##contig= +##ALT= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##INFO= +##INFO= +##FORMAT= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT HG00100 HG00101 HG00102 +17 1 . A . . . END=301;MinDP=1 GT:DP ./.:5 ./.:1 ./.:3 +17 302 . T TA 488 . INDEL;IDV=7;IMF=1;DP=25;VDB=0.27613;SGB=-4.22417;MQSB=0.0443614;MQ0F=0;ICB=0.8;HOB=0.222222;AC=4;AN=6;DP4=2,4,8,11;MQ=49 GT:PL:DP:DV 0/1:167,0,96:11:6 0/1:157,0,9:7:6 1/1:201,21,0:7:7 +17 303 . G . . . END=827;MinDP=2 GT:DP 0/0:9 0/0:2 0/0:3 +17 828 . T C 409 . DP=25;VDB=0.842082;SGB=-4.20907;RPB=0.950652;MQB=1;MQSB=1;BQB=0.929717;MQ0F=0;ICB=0.8;HOB=0.222222;AC=4;AN=6;DP4=2,4,8,11;MQ=60 GT:PL:DP:DV 0/1:211,0,35:12:10 0/1:116,0,91:9:5 1/1:120,12,0:4:4 +17 829 . T . . . END=833;MinDP=4 GT:DP 0/0:11 0/0:8 0/0:4 +17 834 . G A 364 . DP=25;VDB=0.788006;SGB=-4.01214;RPB=0.999233;MQB=1;MQSB=1;BQB=0.821668;MQ0F=0;ICB=0.8;HOB=0.222222;AC=4;AN=6;DP4=2,3,7,10;MQ=60 GT:PL:DP:DV 0/1:185,0,46:11:9 0/1:128,0,59:8:5 1/1:89,9,0:3:3 +17 835 . T . . . END=1664;MinDP=1 GT:DP 0/0:5 0/0:2 0/0:1 +17 1665 . T C 3.10665 . DP=20;VDB=0.1;SGB=0.346553;RPB=0.222222;MQB=0.611111;MQSB=0.988166;BQB=0.944444;MQ0F=0;ICB=0.128205;HOB=0.0555556;AC=1;AN=6;DP4=7,11,1,1;MQ=55 GT:PL:DP:DV 0/0:0,21,185:7:0 0/0:0,27,222:9:0 0/1:35,0,51:4:2 +17 1666 . G . . . END=1868;MinDP=0 GT:DP 0/0:6 0/0:0 0/0:1 +17 1869 . A T 138 . DP=24;VDB=0.928022;SGB=-11.9537;RPB=0.984127;MQB=0.96464;MQSB=0.931547;BQB=0.359155;MQ0F=0;ICB=0.8;HOB=0.222222;AC=4;AN=6;DP4=6,9,5,4;MQ=58 GT:PL:DP:DV 0/1:115,0,224:18:7 0/1:16,0,104:5:1 1/1:42,3,0:1:1 +17 1870 . C . . . END=2040;MinDP=1 GT:DP 0/0:13 0/0:2 0/0:1 +17 2041 . G A 447 . DP=31;VDB=0.816435;SGB=-4.18892;RPB=0.88473;MQB=0.972375;MQSB=0.968257;BQB=0.311275;MQ0F=0;ICB=0.8;HOB=0.222222;AC=4;AN=6;DP4=6,5,12,7;MQ=58 GT:PL:DP:DV 0/1:229,0,212:21:11 0/1:32,0,24:2:1 1/1:223,21,0:7:7 +17 2042 . G . . . END=2219;MinDP=1 GT:DP 0/0:8 0/0:1 0/0:3 +17 2220 . G A 303 . DP=21;VDB=0.532753;SGB=-3.51597;RPB=0.964198;MQB=0.898397;MQSB=0.875769;BQB=0.0354359;MQ0F=0;ICB=0.8;HOB=0.222222;AC=4;AN=6;DP4=6,2,1,11;MQ=58 GT:PL:DP:DV 0/1:139,0,130:12:6 0/1:69,0,46:4:2 1/1:131,12,0:4:4 +17 2221 . G . . . END=2563;MinDP=0 GT:DP 0/0:5 0/0:0 0/0:2 +17 2564 . A G 233 . DP=15;VDB=0.690812;SGB=-3.20711;RPB=0.197899;MQB=1;MQSB=1;BQB=0.965069;MQ0F=0;ICB=0.8;HOB=0.222222;AC=4;AN=6;DP4=1,4,4,5;MQ=60 GT:PL:DP:DV 0/1:88,0,78:6:3 0/1:57,0,56:4:2 1/1:124,12,0:4:4 +17 2565 . A . . . END=3103;MinDP=0 GT:DP 0/0:6 0/0:0 0/0:1 +17 3104 . C T 24.2837 . DP=25;VDB=0.8;SGB=0.346553;RPB=0.717391;MQB=0.956522;MQSB=0.962269;BQB=0.978261;MQ0F=0;ICB=0.128205;HOB=0.0555556;AC=1;AN=6;DP4=8,15,2,0;MQ=58 GT:PL:DP:DV 0/0:0,48,255:16:0 0/0:0,12,144:4:0 0/1:59,0,93:5:2 +17 3105 . T . . . END=3586;MinDP=2 GT:DP 0/0:5 0/0:2 0/0:3 +17 3587 . G A 358 . DP=29;VDB=0.902044;SGB=-3.91326;RPB=0.800999;MQB=1;MQSB=1;BQB=0.156944;MQ0F=0;ICB=0.8;HOB=0.222222;AC=4;AN=6;DP4=4,7,10,6;MQ=60 GT:PL:DP:DV 0/1:161,0,184:14:7 0/1:22,0,118:5:1 1/1:212,24,0:8:8 +17 3588 . A . . . END=3935;MinDP=2 GT:DP 0/0:10 0/0:2 0/0:3 +17 3936 . A G 469 . DP=37;VDB=0.0574114;SGB=-4.60123;RPB=0.741697;MQB=0.812605;MQSB=0.143788;BQB=0.883831;MQ0F=0;ICB=0.8;HOB=0.222222;AC=4;AN=6;DP4=5,6,6,17;MQ=56 GT:PL:DP:DV 0/1:233,0,206:20:11 0/1:77,0,58:6:4 1/1:196,24,0:8:8 +17 3937 . C . . . END=4101;MinDP=0 GT:DP 0/0:1 0/0:0 0/0:0 diff --git a/test/mpileup.2.samples b/test/mpileup.2.samples new file mode 100644 index 0000000..07b1eae --- /dev/null +++ b/test/mpileup.2.samples @@ -0,0 +1,3 @@ +HG00100 2 +HG00101 1 +HG00102 2 diff --git a/test/mpileup.X.2.out b/test/mpileup.X.2.out new file mode 100644 index 0000000..ab82d46 --- /dev/null +++ b/test/mpileup.X.2.out @@ -0,0 +1,40 @@ +##fileformat=VCFv4.2 +##FILTER= +##samtoolsVersion=1.1-19-g6b249e2+htslib-1.1-74-g845c515 +##samtoolsCommand=samtools mpileup -uvDV -b xxx//mpileup.bam.list -f xxx//mpileup.ref.fa.gz +##reference=file://xxx//mpileup.ref.fa.gz +##contig= +##ALT= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT HG00100 HG00101 HG00102 +X 302 . T TA 482 . INDEL;IDV=7;IMF=1;DP=25;VDB=0.27613;SGB=-4.22417;MQSB=0.0443614;MQ0F=0;ICB=0.235294;HOB=0.18;AC=4;AN=5;DP4=2,4,8,11;MQ=49 GT:PL:DP:DV 0/1:167,0,96:11:6 1:157,9:7:6 1/1:201,21,0:7:7 +X 828 . T C 322 . DP=25;VDB=0.842082;SGB=-4.20907;RPB=0.950652;MQB=1;MQSB=1;BQB=0.929717;MQ0F=0;ICB=0.235294;HOB=0.18;AC=4;AN=5;DP4=2,4,8,11;MQ=60 GT:PL:DP:DV 0/1:211,0,35:12:10 1:116,91:9:5 1/1:120,12,0:4:4 +X 834 . G A 309 . DP=25;VDB=0.788006;SGB=-4.01214;RPB=0.999233;MQB=1;MQSB=1;BQB=0.821668;MQ0F=0;ICB=0.235294;HOB=0.18;AC=4;AN=5;DP4=2,3,7,10;MQ=60 GT:PL:DP:DV 0/1:185,0,46:11:9 1:128,59:8:5 1/1:89,9,0:3:3 +X 1665 . T C 3.44176 . DP=20;VDB=0.1;SGB=0.346553;RPB=0.222222;MQB=0.611111;MQSB=0.988166;BQB=0.944444;MQ0F=0;ICB=0.235294;HOB=0.18;AC=1;AN=5;DP4=7,11,1,1;MQ=55 GT:PL:DP:DV 0/0:0,21,185:7:0 0:0,222:9:0 0/1:35,0,51:4:2 +X 1869 . A T 122 . DP=24;VDB=0.928022;SGB=-11.9537;RPB=0.984127;MQB=0.96464;MQSB=0.931547;BQB=0.359155;MQ0F=0;ICB=0.461538;HOB=0.02;AC=3;AN=5;DP4=6,9,5,4;MQ=58 GT:PL:DP:DV 0/1:115,0,224:18:7 0:16,104:5:1 1/1:42,3,0:1:1 +X 2041 . G A 426 . DP=31;VDB=0.816435;SGB=-4.18892;RPB=0.88473;MQB=0.972375;MQSB=0.968257;BQB=0.311275;MQ0F=0;ICB=0.235294;HOB=0.18;AC=4;AN=5;DP4=6,5,12,7;MQ=58 GT:PL:DP:DV 0/1:229,0,212:21:11 1:32,24:2:1 1/1:223,21,0:7:7 +X 2220 . G A 259 . DP=21;VDB=0.532753;SGB=-3.51597;RPB=0.964198;MQB=0.898397;MQSB=0.875769;BQB=0.0354359;MQ0F=0;ICB=0.235294;HOB=0.18;AC=4;AN=5;DP4=6,2,1,11;MQ=58 GT:PL:DP:DV 0/1:139,0,130:12:6 1:69,46:4:2 1/1:131,12,0:4:4 +X 2564 . A G 180 . DP=15;VDB=0.690812;SGB=-3.20711;RPB=0.197899;MQB=1;MQSB=1;BQB=0.965069;MQ0F=0;ICB=0.235294;HOB=0.18;AC=4;AN=5;DP4=1,4,4,5;MQ=60 GT:PL:DP:DV 0/1:88,0,78:6:3 1:57,56:4:2 1/1:124,12,0:4:4 +X 3104 . C T 24.8375 . DP=25;VDB=0.8;SGB=0.346553;RPB=0.717391;MQB=0.956522;MQSB=0.962269;BQB=0.978261;MQ0F=0;ICB=0.235294;HOB=0.18;AC=1;AN=5;DP4=8,15,2,0;MQ=58 GT:PL:DP:DV 0/0:0,48,255:16:0 0:0,144:4:0 0/1:59,0,93:5:2 +X 3587 . G A 335 . DP=29;VDB=0.902044;SGB=-3.91326;RPB=0.800999;MQB=1;MQSB=1;BQB=0.156944;MQ0F=0;ICB=0.461538;HOB=0.02;AC=3;AN=5;DP4=4,7,10,6;MQ=60 GT:PL:DP:DV 0/1:161,0,184:14:7 0:22,118:5:1 1/1:212,24,0:8:8 +X 3936 . A G 414 . DP=37;VDB=0.0574114;SGB=-4.60123;RPB=0.741697;MQB=0.812605;MQSB=0.143788;BQB=0.883831;MQ0F=0;ICB=0.235294;HOB=0.18;AC=4;AN=5;DP4=5,6,6,17;MQ=56 GT:PL:DP:DV 0/1:233,0,206:20:11 1:77,58:6:4 1/1:196,24,0:8:8 diff --git a/test/mpileup.X.out b/test/mpileup.X.out new file mode 100644 index 0000000..0e63b8e --- /dev/null +++ b/test/mpileup.X.out @@ -0,0 +1,40 @@ +##fileformat=VCFv4.2 +##FILTER= +##samtoolsVersion=1.1-19-g6b249e2+htslib-1.1-74-g845c515 +##samtoolsCommand=samtools mpileup -uvDV -b xxx//mpileup.bam.list -f xxx//mpileup.ref.fa.gz +##reference=file://xxx//mpileup.ref.fa.gz +##contig= +##ALT= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT HG00100 HG00101 HG00102 +X 302 . T TA 482 . INDEL;IDV=7;IMF=1;DP=25;VDB=0.27613;SGB=-4.22417;MQSB=0.0443614;MQ0F=0;ICB=0.235294;HOB=0.18;AC=4;AN=5;DP4=2,4,8,11;MQ=49 GT:PL:DP:DV 0/1:167,0,96:11:6 1:157,9:7:6 1/1:201,21,0:7:7 +X 828 . T C 322 . DP=25;VDB=0.842082;SGB=-4.20907;RPB=0.950652;MQB=1;MQSB=1;BQB=0.929717;MQ0F=0;ICB=0.235294;HOB=0.18;AC=4;AN=5;DP4=2,4,8,11;MQ=60 GT:PL:DP:DV 0/1:211,0,35:12:10 1:116,91:9:5 1/1:120,12,0:4:4 +X 834 . G A 309 . DP=25;VDB=0.788006;SGB=-4.01214;RPB=0.999233;MQB=1;MQSB=1;BQB=0.821668;MQ0F=0;ICB=0.235294;HOB=0.18;AC=4;AN=5;DP4=2,3,7,10;MQ=60 GT:PL:DP:DV 0/1:185,0,46:11:9 1:128,59:8:5 1/1:89,9,0:3:3 +X 1665 . T C 3.10665 . DP=20;VDB=0.1;SGB=0.346553;RPB=0.222222;MQB=0.611111;MQSB=0.988166;BQB=0.944444;MQ0F=0;ICB=0.128205;HOB=0.0555556;AC=1;AN=6;DP4=7,11,1,1;MQ=55 GT:PL:DP:DV 0/0:0,21,185:7:0 0/0:0,27,222:9:0 0/1:35,0,51:4:2 +X 1869 . A T 138 . DP=24;VDB=0.928022;SGB=-11.9537;RPB=0.984127;MQB=0.96464;MQSB=0.931547;BQB=0.359155;MQ0F=0;ICB=0.8;HOB=0.222222;AC=4;AN=6;DP4=6,9,5,4;MQ=58 GT:PL:DP:DV 0/1:115,0,224:18:7 0/1:16,0,104:5:1 1/1:42,3,0:1:1 +X 2041 . G A 447 . DP=31;VDB=0.816435;SGB=-4.18892;RPB=0.88473;MQB=0.972375;MQSB=0.968257;BQB=0.311275;MQ0F=0;ICB=0.8;HOB=0.222222;AC=4;AN=6;DP4=6,5,12,7;MQ=58 GT:PL:DP:DV 0/1:229,0,212:21:11 0/1:32,0,24:2:1 1/1:223,21,0:7:7 +X 2220 . G A 303 . DP=21;VDB=0.532753;SGB=-3.51597;RPB=0.964198;MQB=0.898397;MQSB=0.875769;BQB=0.0354359;MQ0F=0;ICB=0.8;HOB=0.222222;AC=4;AN=6;DP4=6,2,1,11;MQ=58 GT:PL:DP:DV 0/1:139,0,130:12:6 0/1:69,0,46:4:2 1/1:131,12,0:4:4 +X 2564 . A G 233 . DP=15;VDB=0.690812;SGB=-3.20711;RPB=0.197899;MQB=1;MQSB=1;BQB=0.965069;MQ0F=0;ICB=0.8;HOB=0.222222;AC=4;AN=6;DP4=1,4,4,5;MQ=60 GT:PL:DP:DV 0/1:88,0,78:6:3 0/1:57,0,56:4:2 1/1:124,12,0:4:4 +X 3104 . C T 24.8375 . DP=25;VDB=0.8;SGB=0.346553;RPB=0.717391;MQB=0.956522;MQSB=0.962269;BQB=0.978261;MQ0F=0;ICB=0.235294;HOB=0.18;AC=1;AN=5;DP4=8,15,2,0;MQ=58 GT:PL:DP:DV 0/0:0,48,255:16:0 0:0,144:4:0 0/1:59,0,93:5:2 +X 3587 . G A 335 . DP=29;VDB=0.902044;SGB=-3.91326;RPB=0.800999;MQB=1;MQSB=1;BQB=0.156944;MQ0F=0;ICB=0.461538;HOB=0.02;AC=3;AN=5;DP4=4,7,10,6;MQ=60 GT:PL:DP:DV 0/1:161,0,184:14:7 0:22,118:5:1 1/1:212,24,0:8:8 +X 3936 . A G 414 . DP=37;VDB=0.0574114;SGB=-4.60123;RPB=0.741697;MQB=0.812605;MQSB=0.143788;BQB=0.883831;MQ0F=0;ICB=0.235294;HOB=0.18;AC=4;AN=5;DP4=5,6,6,17;MQ=56 GT:PL:DP:DV 0/1:233,0,206:20:11 1:77,58:6:4 1/1:196,24,0:8:8 diff --git a/test/mpileup.X.vcf b/test/mpileup.X.vcf new file mode 100644 index 0000000..ea2983a --- /dev/null +++ b/test/mpileup.X.vcf @@ -0,0 +1,4127 @@ +##fileformat=VCFv4.2 +##FILTER= +##samtoolsVersion=1.1-19-g6b249e2+htslib-1.1-74-g845c515 +##samtoolsCommand=samtools mpileup -uvDV -b xxx//mpileup.bam.list -f xxx//mpileup.ref.fa.gz +##reference=file://xxx//mpileup.ref.fa.gz +##contig= +##ALT= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT HG00100 HG00101 HG00102 +X 1 . A <*> 0 . DP=11;I16=11,0,0,0,452,18594,0,0,319,9251,0,0,223,4959,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 +X 2 . A <*> 0 . DP=11;I16=11,0,0,0,439,17587,0,0,319,9251,0,0,226,5030,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 +X 3 . G <*> 0 . DP=11;I16=11,0,0,0,431,16971,0,0,319,9251,0,0,229,5111,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 +X 4 . C <*> 0 . DP=11;I16=11,0,0,0,423,16417,0,0,319,9251,0,0,232,5202,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,71:3:0 +X 5 . T <*> 0 . DP=11;I16=11,0,0,0,450,18520,0,0,319,9251,0,0,234,5252,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 +X 6 . T <*> 0 . DP=11;I16=11,0,0,0,403,14847,0,0,319,9251,0,0,236,5310,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 +X 7 . C <*> 0 . DP=11;I16=11,0,0,0,446,18114,0,0,319,9251,0,0,237,5327,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 +X 8 . T <*> 0 . DP=11;I16=11,0,0,0,465,19677,0,0,319,9251,0,0,238,5354,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 +X 9 . C <*> 0 . DP=11;I16=11,0,0,0,447,18205,0,0,319,9251,0,0,239,5391,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 +X 10 . A <*> 0 . DP=11;I16=11,0,0,0,426,16756,0,0,319,9251,0,0,240,5438,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,69:3:0 +X 11 . C <*> 0 . DP=11;I16=11,0,0,0,413,15603,0,0,319,9251,0,0,241,5495,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 +X 12 . C <*> 0 . DP=11;I16=11,0,0,0,438,17506,0,0,319,9251,0,0,242,5562,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 +X 13 . C <*> 0 . DP=11;I16=11,0,0,0,437,17463,0,0,319,9251,0,0,243,5639,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 +X 14 . T <*> 0 . DP=11;I16=11,0,0,0,453,18715,0,0,319,9251,0,0,242,5628,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 +X 15 . G <*> 0 . DP=11;I16=11,0,0,0,439,17599,0,0,319,9251,0,0,240,5580,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 +X 16 . T <*> 0 . DP=11;I16=11,0,0,0,426,16546,0,0,319,9251,0,0,238,5544,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 +X 17 . T <*> 0 . DP=11;I16=11,0,0,0,407,15195,0,0,319,9251,0,0,235,5469,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 +X 18 . C <*> 0 . DP=12;I16=12,0,0,0,450,17136,0,0,379,12851,0,0,231,5353,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,113:6:0 0,9,72:3:0 0,9,72:3:0 +X 19 . C <*> 0 . DP=13;I16=13,0,0,0,502,19652,0,0,439,16451,0,0,228,5246,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,112:6:0 0,12,89:4:0 0,9,72:3:0 +X 20 . T <*> 0 . DP=13;I16=13,0,0,0,532,21878,0,0,439,16451,0,0,226,5150,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,116:6:0 0,12,98:4:0 0,9,72:3:0 +X 21 . G <*> 0 . DP=13;I16=13,0,0,0,498,19254,0,0,439,16451,0,0,224,5066,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,117:6:0 0,12,94:4:0 0,9,72:3:0 +X 22 . C <*> 0 . DP=13;I16=13,0,0,0,511,20289,0,0,470,19210,0,0,223,4993,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,115:6:0 0,12,91:4:0 0,9,76:3:0 +X 23 . A <*> 0 . DP=14;I16=14,0,0,0,513,19399,0,0,530,22810,0,0,223,4931,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,133:7:0 0,12,82:4:0 0,9,82:3:0 +X 24 . T <*> 0 . DP=14;I16=14,0,0,0,534,20540,0,0,530,22810,0,0,224,4882,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,131:7:0 0,12,96:4:0 0,9,80:3:0 +X 25 . A <*> 0 . DP=15;I16=15,0,0,0,561,21133,0,0,590,26410,0,0,225,4847,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,140:8:0 0,12,96:4:0 0,9,81:3:0 +X 26 . G <*> 0 . DP=15;I16=15,0,0,0,591,23429,0,0,590,26410,0,0,227,4827,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,151:8:0 0,12,96:4:0 0,9,81:3:0 +X 27 . A <*> 0 . DP=15;I16=15,0,0,0,588,23120,0,0,590,26410,0,0,229,4823,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,146:8:0 0,12,98:4:0 0,9,83:3:0 +X 28 . T <*> 0 . DP=16;I16=16,0,0,0,605,23001,0,0,650,30010,0,0,231,4835,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,147:8:0 0,12,97:4:0 0,12,101:4:0 +X 29 . A <*> 0 . DP=17;I16=17,0,0,0,615,22533,0,0,710,33610,0,0,234,4864,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,146:8:0 0,15,102:5:0 0,12,104:4:0 +X 30 . A <*> 0 . DP=17;I16=17,0,0,0,660,25914,0,0,710,33610,0,0,238,4912,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,149:8:0 0,15,115:5:0 0,12,108:4:0 +X 31 . T <*> 0 . DP=17;I16=17,0,0,0,656,25392,0,0,710,33610,0,0,242,4980,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,150:8:0 0,15,113:5:0 0,12,105:4:0 +X 32 . T <*> 0 . DP=17;I16=17,0,0,0,605,21789,0,0,741,36369,0,0,247,5067,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,143:8:0 0,15,104:5:0 0,12,104:4:0 +X 33 . G <*> 0 . DP=17;I16=17,0,0,0,659,25757,0,0,741,36369,0,0,252,5124,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,158:8:0 0,15,118:5:0 0,12,105:4:0 +X 34 . C <*> 0 . DP=17;I16=17,0,0,0,658,25704,0,0,741,36369,0,0,257,5203,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,151:8:0 0,15,121:5:0 0,12,106:4:0 +X 35 . A <*> 0 . DP=18;I16=18,0,0,0,677,25881,0,0,801,39969,0,0,262,5304,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,152:8:0 0,15,109:5:0 0,15,121:5:0 +X 36 . T <*> 0 . DP=18;I16=18,0,0,0,678,25796,0,0,801,39969,0,0,268,5428,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,151:8:0 0,15,114:5:0 0,15,125:5:0 +X 37 . G <*> 0 . DP=18;I16=18,0,0,0,685,26291,0,0,801,39969,0,0,274,5576,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,157:8:0 0,15,116:5:0 0,15,126:5:0 +X 38 . A <*> 0 . DP=18;I16=18,0,0,0,697,27245,0,0,801,39969,0,0,280,5748,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,152:8:0 0,15,116:5:0 0,15,129:5:0 +X 39 . C <*> 0 . DP=16;I16=16,0,0,0,591,22311,0,0,743,38287,0,0,288,5942,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,148:7:0 0,12,94:4:0 0,15,123:5:0 +X 40 . A <*> 0 . DP=16;I16=16,0,0,0,630,24896,0,0,743,38287,0,0,295,6107,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,146:7:0 0,12,104:4:0 0,15,127:5:0 +X 41 . A <*> 0 . DP=17;I16=17,0,0,0,645,24685,0,0,803,41887,0,0,302,6294,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,151:8:0 0,12,104:4:0 0,15,131:5:0 +X 42 . T <*> 0 . DP=17;I16=17,0,0,0,618,23118,0,0,803,41887,0,0,310,6504,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,155:8:0 0,12,82:4:0 0,15,127:5:0 +X 43 . T <*> 0 . DP=17;I16=17,0,0,0,631,23689,0,0,803,41887,0,0,318,6738,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,151:8:0 0,12,101:4:0 0,15,129:5:0 +X 44 . G <*> 0 . DP=17;I16=17,0,0,0,664,26162,0,0,803,41887,0,0,324,6896,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,164:8:0 0,12,100:4:0 0,15,129:5:0 +X 45 . C <*> 0 . DP=17;I16=17,0,0,0,657,25525,0,0,803,41887,0,0,329,7027,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,163:8:0 0,12,108:4:0 0,15,125:5:0 +X 46 . C <*> 0 . DP=17;I16=17,0,0,0,646,25244,0,0,803,41887,0,0,334,7180,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,161:8:0 0,12,98:4:0 0,15,131:5:0 +X 47 . T <*> 0 . DP=17;I16=17,0,0,0,700,28998,0,0,803,41887,0,0,339,7355,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,165:8:0 0,12,110:4:0 0,15,136:5:0 +X 48 . T <*> 0 . DP=17;I16=17,0,0,0,648,25020,0,0,803,41887,0,0,343,7501,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,155:8:0 0,12,105:4:0 0,15,131:5:0 +X 49 . G <*> 0 . DP=18;I16=18,0,0,0,686,26674,0,0,832,42728,0,0,346,7616,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,158:8:0 0,15,119:5:0 0,15,128:5:0 +X 50 . T <*> 0 . DP=18;I16=17,0,0,0,650,24972,0,0,772,39128,0,0,332,7426,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,155:8:0 0,12,101:4:0 0,15,128:5:0 +X 51 . C <*> 0 . DP=18;I16=18,0,0,0,681,26529,0,0,832,42728,0,0,353,7853,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,167:8:0 0,15,99:5:0 0,15,127:5:0 +X 52 . C <*> 0 . DP=18;I16=17,0,0,0,645,24983,0,0,803,41887,0,0,353,7965,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,164:8:0 0,12,99:4:0 0,15,128:5:0 +X 53 . C <*> 0 . DP=18;I16=18,0,0,0,687,26735,0,0,832,42728,0,0,359,8113,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,164:8:0 0,15,113:5:0 0,15,132:5:0 +X 54 . T <*> 0 . DP=18;I16=18,0,0,0,736,30194,0,0,832,42728,0,0,361,8219,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,163:8:0 0,15,128:5:0 0,15,136:5:0 +X 55 . G <*> 0 . DP=18;I16=18,0,0,0,674,26082,0,0,832,42728,0,0,362,8290,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,168:8:0 0,15,112:5:0 0,15,122:5:0 +X 56 . C <*> 0 . DP=18;I16=18,0,0,0,701,27645,0,0,832,42728,0,0,363,8375,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,162:8:0 0,15,121:5:0 0,15,131:5:0 +X 57 . T <*> 0 . DP=18;I16=17,0,0,0,694,29118,0,0,803,41887,0,0,356,8410,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,163:8:0 0,12,117:4:0 0,15,138:5:0 +X 58 . G <*> 0 . DP=17;I16=16,0,0,0,616,24356,0,0,774,41046,0,0,356,8454,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,159:7:0 0,12,95:4:0 0,15,131:5:0 +X 59 . A <*> 0 . DP=17;I16=17,0,0,0,656,26038,0,0,803,41887,0,0,366,8606,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,155:7:0 0,15,116:5:0 0,15,134:5:0 +X 60 . A <*> 0 . DP=17;I16=17,0,0,0,663,26463,0,0,803,41887,0,0,367,8687,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,151:7:0 0,15,127:5:0 0,15,138:5:0 +X 61 . T <*> 0 . DP=17;I16=16,0,0,0,605,23215,0,0,774,41046,0,0,355,8583,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,152:7:0 0,12,101:4:0 0,15,131:5:0 +X 62 . G <*> 0 . DP=18;I16=17,0,0,0,646,24868,0,0,834,44646,0,0,353,8557,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,158:7:0 0,12,103:4:0 0,18,141:6:0 +X 63 . T <*> 0 . DP=18;I16=17,0,0,0,590,21682,0,0,803,41887,0,0,341,8111,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,148:7:0 0,12,80:4:0 0,18,144:6:0 +X 64 . G <*> 0 . DP=19;I16=19,0,0,0,696,26416,0,0,923,49087,0,0,366,8758,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,169:8:0 0,15,103:5:0 0,18,142:6:0 +X 65 . C <*> 0 . DP=18;I16=18,0,0,0,686,26512,0,0,894,48246,0,0,367,8743,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,163:7:0 0,15,116:5:0 0,18,147:6:0 +X 66 . T <*> 0 . DP=18;I16=17,0,0,0,691,28315,0,0,834,44646,0,0,342,8068,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,164:7:0 0,12,110:4:0 0,18,153:6:0 +X 67 . C <*> 0 . DP=17;I16=17,0,0,0,645,25313,0,0,834,44646,0,0,341,7983,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,163:7:0 0,12,94:4:0 0,18,147:6:0 +X 68 . T <*> 0 . DP=17;I16=17,0,0,0,691,28307,0,0,834,44646,0,0,339,7863,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,165:7:0 0,12,108:4:0 0,18,151:6:0 +X 69 . G <*> 0 . DP=17;I16=17,0,0,0,657,25721,0,0,865,47405,0,0,338,7758,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,172:8:0 0,9,93:3:0 0,18,142:6:0 +X 70 . G <*> 0 . DP=17;I16=16,0,0,0,575,21391,0,0,836,46564,0,0,317,7227,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,162:8:0 0,6,64:2:0 0,18,141:6:0 +X 71 . G <*> 0 . DP=17;I16=15,0,0,0,571,21975,0,0,776,42964,0,0,307,7029,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,170:8:0 0,6,72:2:0 0,15,130:5:0 +X 72 . G <*> 0 . DP=17;I16=15,0,0,0,572,22002,0,0,776,42964,0,0,305,6907,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,171:8:0 0,6,65:2:0 0,15,131:5:0 +X 73 . T <*> 0 . DP=18;I16=16,0,0,0,623,25301,0,0,836,46564,0,0,314,6918,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,158:8:0 0,6,94:2:0 0,18,143:6:0 +X 74 . C <*> 0 . DP=18;I16=17,0,0,0,674,28110,0,0,865,47405,0,0,338,7468,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,176:8:0 0,9,106:3:0 0,18,141:6:0 +X 75 . T <*> 0 . DP=18;I16=16,0,0,0,685,30675,0,0,836,46564,0,0,312,6782,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,175:8:0 0,6,90:2:0 0,18,150:6:0 +X 76 . C <*> 0 . DP=18;I16=17,0,0,0,683,29481,0,0,865,47405,0,0,336,7360,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,174:8:0 0,9,98:3:0 0,18,148:6:0 +X 77 . T <*> 0 . DP=18;I16=16,0,0,0,710,33072,0,0,836,46564,0,0,310,6702,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,179:8:0 0,6,92:2:0 0,18,154:6:0 +X 78 . G <*> 0 . DP=18;I16=16,0,0,0,692,31158,0,0,836,46564,0,0,309,6683,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,180:8:0 0,6,94:2:0 0,18,149:6:0 +X 79 . G <*> 0 . DP=18;I16=15,0,0,0,605,26629,0,0,776,42964,0,0,283,6053,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,168:8:0 0,3,60:1:0 0,18,149:6:0 +X 80 . G <*> 0 . DP=18;I16=17,0,0,0,688,30128,0,0,865,47405,0,0,332,7312,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,173:8:0 0,9,106:3:0 0,18,151:6:0 +X 81 . G <*> 0 . DP=18;I16=16,0,0,0,631,27429,0,0,836,46564,0,0,326,7310,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,165:7:0 0,9,97:3:0 0,18,145:6:0 +X 82 . T <*> 0 . DP=18;I16=15,0,0,0,559,22735,0,0,776,42964,0,0,280,6122,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,154:8:0 0,3,60:1:0 0,18,131:6:0 +X 83 . C <*> 0 . DP=18;I16=16,0,0,0,622,27146,0,0,836,46564,0,0,304,6798,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,170:8:0 0,6,75:2:0 0,18,145:6:0 +X 84 . T <*> 0 . DP=18;I16=17,0,0,0,705,32445,0,0,865,47405,0,0,328,7488,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,181:8:0 0,9,85:3:0 0,18,154:6:0 +X 85 . C <*> 0 . DP=18;I16=17,0,0,0,708,31222,0,0,865,47405,0,0,327,7567,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,181:8:0 0,9,108:3:0 0,18,153:6:0 +X 86 . A <*> 0 . DP=18;I16=17,0,0,0,692,29540,0,0,865,47405,0,0,326,7660,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,169:8:0 0,9,111:3:0 0,18,149:6:0 +X 87 . C <*> 0 . DP=18;I16=17,0,0,0,683,29493,0,0,896,50164,0,0,326,7766,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,174:8:0 0,9,103:3:0 0,18,148:6:0 +X 88 . C <*> 0 . DP=18;I16=17,0,0,0,703,31005,0,0,896,50164,0,0,326,7834,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,174:8:0 0,9,113:3:0 0,18,153:6:0 +X 89 . C <*> 0 . DP=18;I16=17,0,0,0,697,30875,0,0,896,50164,0,0,326,7914,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,176:8:0 0,9,103:3:0 0,18,154:6:0 +X 90 . A <*> 0 . DP=17;I16=16,0,0,0,668,29732,0,0,867,49323,0,0,326,7954,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,173:8:0 0,9,114:3:0 0,15,138:5:0 +X 91 . C <*> 0 . DP=16;I16=15,0,0,0,613,26409,0,0,838,48482,0,0,327,8001,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,170:7:0 0,9,113:3:0 0,15,133:5:0 +X 92 . G <*> 0 . DP=16;I16=15,0,0,0,499,18731,0,0,838,48482,0,0,328,8054,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,143:7:0 0,9,100:3:0 0,15,96:5:0 +X 93 . A <*> 0 . DP=16;I16=15,0,0,0,635,28655,0,0,869,51241,0,0,329,8063,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,167:7:0 0,9,108:3:0 0,15,145:5:0 +X 94 . C <*> 0 . DP=16;I16=15,0,0,0,607,25893,0,0,869,51241,0,0,331,8079,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,166:7:0 0,9,105:3:0 0,15,135:5:0 +X 95 . C <*> 0 . DP=17;I16=15,0,0,0,615,26761,0,0,900,54000,0,0,306,7378,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,178:8:0 0,6,91:2:0 0,15,135:5:0 +X 96 . A <*> 0 . DP=17;I16=16,0,0,0,625,26705,0,0,929,54841,0,0,332,7936,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,172:8:0 0,9,99:3:0 0,15,134:5:0 +X 97 . A <*> 0 . DP=18;I16=17,0,0,0,675,29017,0,0,958,55682,0,0,333,7879,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,179:9:0 0,9,104:3:0 0,15,145:5:0 +X 98 . C <*> 0 . DP=18;I16=17,0,0,0,655,27231,0,0,958,55682,0,0,333,7735,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,179:9:0 0,9,105:3:0 0,15,131:5:0 +X 99 . T <*> 0 . DP=18;I16=17,0,0,0,720,32840,0,0,958,55682,0,0,333,7607,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,186:9:0 0,9,115:3:0 0,15,153:5:0 +X 100 . C <*> 0 . DP=18;I16=17,0,0,0,688,29762,0,0,958,55682,0,0,332,7446,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,189:9:0 0,9,108:3:0 0,15,134:5:0 +X 101 . C <*> 0 . DP=18;I16=17,0,0,0,650,27530,0,0,958,55682,0,0,331,7303,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,182:9:0 0,9,99:3:0 0,15,132:5:0 +X 102 . C <*> 0 . DP=18;I16=17,0,0,0,695,30453,0,0,958,55682,0,0,330,7178,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,188:9:0 0,9,111:3:0 0,15,139:5:0 +X 103 . T <*> 0 . DP=18;I16=16,0,0,0,692,31998,0,0,929,54841,0,0,323,7035,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,189:8:0 0,9,108:3:0 0,15,147:5:0 +X 104 . G <*> 0 . DP=18;I16=15,0,0,0,611,26723,0,0,900,54000,0,0,295,6259,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,178:8:0 0,6,89:2:0 0,15,133:5:0 +X 105 . G <*> 0 . DP=19;I16=17,0,0,0,604,23936,0,0,989,58441,0,0,317,6751,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,170:9:0 0,9,97:3:0 0,15,125:5:0 +X 106 . G <*> 0 . DP=19;I16=17,0,0,0,644,26574,0,0,989,58441,0,0,299,6093,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,30,190:10:0 0,6,85:2:0 0,15,124:5:0 +X 107 . C <*> 0 . DP=19;I16=17,0,0,0,694,30064,0,0,989,58441,0,0,313,6543,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,192:9:0 0,9,108:3:0 0,15,136:5:0 +X 108 . C <*> 0 . DP=19;I16=17,0,0,0,692,30148,0,0,989,58441,0,0,310,6420,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,190:9:0 0,9,108:3:0 0,15,135:5:0 +X 109 . T <*> 0 . DP=19;I16=17,0,0,0,741,34273,0,0,989,58441,0,0,307,6319,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,195:9:0 0,9,110:3:0 0,15,150:5:0 +X 110 . G <*> 0 . DP=19;I16=17,0,0,0,704,31276,0,0,989,58441,0,0,304,6240,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,194:9:0 0,9,104:3:0 0,15,136:5:0 +X 111 . G <*> 0 . DP=19;I16=16,0,0,0,584,24362,0,0,929,54841,0,0,272,5416,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,30,167:10:0 0,6,88:2:0 0,12,118:4:0 +X 112 . C <*> 0 . DP=19;I16=17,0,0,0,680,29854,0,0,989,58441,0,0,296,6052,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,191:9:0 0,9,95:3:0 0,15,135:5:0 +X 113 . A <*> 0 . DP=19;I16=16,0,0,0,645,28035,0,0,960,57600,0,0,266,5318,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,176:9:0 0,6,87:2:0 0,15,139:5:0 +X 114 . C <*> 0 . DP=19;I16=17,0,0,0,674,28788,0,0,989,58441,0,0,286,5856,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,182:9:0 0,9,103:3:0 0,15,133:5:0 +X 115 . C <*> 0 . DP=21;I16=18,0,0,0,708,30546,0,0,1049,62041,0,0,274,5490,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,30,189:10:0 0,6,89:2:0 0,18,147:6:0 +X 116 . A <*> 0 . DP=21;I16=17,1,0,0,727,31755,0,0,1049,62041,0,0,253,5079,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,183:9:0 0,6,90:2:0 0,21,175:7:0 +X 117 . G <*> 0 . DP=21;I16=17,1,0,0,723,31221,0,0,1049,62041,0,0,249,5019,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,186:9:0 0,6,86:2:0 0,21,177:7:0 +X 118 . G <*> 0 . DP=20;I16=16,1,0,0,636,26574,0,0,958,55682,0,0,266,5426,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,175:9:0 0,3,60:1:0 0,21,162:7:0 +X 119 . G <*> 0 . DP=19;I16=16,1,0,0,629,26439,0,0,958,55682,0,0,267,5553,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,175:8:0 0,6,73:2:0 0,21,160:7:0 +X 120 . A <*> 0 . DP=19;I16=16,1,0,0,672,29188,0,0,958,55682,0,0,264,5518,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,175:8:0 0,6,83:2:0 0,21,171:7:0 +X 121 . G <*> 0 . DP=19;I16=16,1,0,0,662,28460,0,0,958,55682,0,0,260,5454,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,181:8:0 0,6,80:2:0 0,21,168:7:0 +X 122 . C <*> 0 . DP=20;I16=17,1,0,0,716,31224,0,0,1018,59282,0,0,256,5410,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,181:8:0 0,9,99:3:0 0,21,178:7:0 +X 123 . T <*> 0 . DP=18;I16=15,1,0,0,661,29997,0,0,898,52082,0,0,255,5385,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,167:7:0 0,9,112:3:0 0,18,166:6:0 +X 124 . T <*> 0 . DP=19;I16=17,1,0,0,626,24802,0,0,987,56523,0,0,279,6003,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,154:9:0 0,9,104:3:0 0,18,154:6:0 +X 125 . A <*> 0 . DP=18;I16=15,1,0,0,611,25689,0,0,898,52082,0,0,254,5340,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,154:7:0 0,9,104:3:0 0,18,162:6:0 +X 126 . A <*> 0 . DP=18;I16=16,1,0,0,648,27366,0,0,927,52923,0,0,279,5947,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,162:8:0 0,9,107:3:0 0,18,174:6:0 +X 127 . C <*> 0 . DP=18;I16=16,1,0,0,646,26972,0,0,927,52923,0,0,279,5949,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,163:8:0 0,9,109:3:0 0,18,160:6:0 +X 128 . A <*> 0 . DP=18;I16=16,1,0,0,673,28797,0,0,927,52923,0,0,279,5971,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,169:8:0 0,9,111:3:0 0,18,162:6:0 +X 129 . A <*> 0 . DP=17;I16=15,1,0,0,645,27891,0,0,867,49323,0,0,280,6012,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,168:8:0 0,9,113:3:0 0,15,159:5:0 +X 130 . A <*> 0 . DP=17;I16=15,1,0,0,641,27295,0,0,867,49323,0,0,281,6071,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,169:8:0 0,9,113:3:0 0,15,152:5:0 +X 131 . C <*> 0 . DP=16;I16=14,1,0,0,606,25732,0,0,838,48482,0,0,256,5472,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,167:7:0 0,9,110:3:0 0,15,147:5:0 +X 132 . A <*> 0 . DP=16;I16=14,1,0,0,627,27579,0,0,838,48482,0,0,256,5514,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,169:7:0 0,9,110:3:0 0,15,151:5:0 +X 133 . T <*> 0 . DP=15;I16=13,2,0,0,584,22816,0,0,838,48482,0,0,282,6196,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,163:7:0 0,9,105:3:0 0,15,150:5:0 +X 134 . C <*> 0 . DP=15;I16=13,2,0,0,607,24653,0,0,838,48482,0,0,283,6267,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,177:7:0 0,9,105:3:0 0,15,152:5:0 +X 135 . T <*> 0 . DP=15;I16=13,2,0,0,600,24178,0,0,838,48482,0,0,284,6352,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,173:7:0 0,9,106:3:0 0,15,156:5:0 +X 136 . G <*> 0 . DP=15;I16=13,2,0,0,574,22258,0,0,838,48482,0,0,286,6450,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,172:7:0 0,9,105:3:0 0,15,134:5:0 +X 137 . T <*> 0 . DP=15;I16=13,2,0,0,563,21377,0,0,838,48482,0,0,289,6561,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,160:7:0 0,9,104:3:0 0,15,139:5:0 +X 138 . C <*> 0 . DP=15;I16=13,2,0,0,584,23088,0,0,838,48482,0,0,291,6637,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,172:7:0 0,9,108:3:0 0,15,142:5:0 +X 139 . C <*> 0 . DP=15;I16=13,2,0,0,554,20790,0,0,838,48482,0,0,292,6680,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,161:7:0 0,9,106:3:0 0,15,143:5:0 +X 140 . A <*> 0 . DP=15;I16=13,2,0,0,583,22789,0,0,838,48482,0,0,292,6690,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,163:7:0 0,9,107:3:0 0,15,153:5:0 +X 141 . G <*> 0 . DP=14;I16=12,2,0,0,534,20750,0,0,778,44882,0,0,292,6664,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,158:6:0 0,9,108:3:0 0,15,142:5:0 +X 142 . C <*> 0 . DP=14;I16=12,2,0,0,503,18593,0,0,778,44882,0,0,292,6650,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,157:6:0 0,9,97:3:0 0,15,129:5:0 +X 143 . G <*> 0 . DP=14;I16=11,2,0,0,415,13657,0,0,718,41282,0,0,285,6599,0,0;QS=3,0;MQSB=0.590909;MQ0F=0 PL:DP:DV 0,18,128:6:0 0,9,95:3:0 0,12,97:4:0 +X 144 . A <*> 0 . DP=14;I16=12,2,0,0,519,19725,0,0,778,44882,0,0,291,6609,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,152:6:0 0,9,105:3:0 0,15,129:5:0 +X 145 . A <*> 0 . DP=14;I16=12,2,0,0,527,20289,0,0,778,44882,0,0,290,6584,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,153:6:0 0,9,106:3:0 0,15,138:5:0 +X 146 . T <*> 0 . DP=14;I16=12,2,0,0,514,19484,0,0,778,44882,0,0,289,6573,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,152:6:0 0,9,103:3:0 0,15,128:5:0 +X 147 . A <*> 0 . DP=14;I16=12,2,0,0,515,19213,0,0,778,44882,0,0,288,6576,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,150:6:0 0,9,99:3:0 0,15,140:5:0 +X 148 . C <*> 0 . DP=14;I16=12,2,0,0,541,21019,0,0,778,44882,0,0,286,6542,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,157:6:0 0,9,106:3:0 0,15,146:5:0 +X 149 . C <*> 0 . DP=14;I16=12,2,0,0,512,19326,0,0,778,44882,0,0,283,6471,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,148:6:0 0,9,109:3:0 0,15,140:5:0 +X 150 . T <*> 0 . DP=13;I16=11,2,0,0,511,20251,0,0,749,44041,0,0,280,6362,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,153:6:0 0,6,84:2:0 0,15,152:5:0 +X 151 . G <*> 0 . DP=13;I16=11,2,0,0,506,19826,0,0,749,44041,0,0,277,6263,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,157:6:0 0,6,84:2:0 0,15,144:5:0 +X 152 . C <*> 0 . DP=14;I16=12,2,0,0,543,21283,0,0,809,47641,0,0,274,6174,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,168:7:0 0,6,84:2:0 0,15,146:5:0 +X 153 . A <*> 0 . DP=14;I16=12,2,0,0,536,20594,0,0,809,47641,0,0,272,6096,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,156:7:0 0,6,81:2:0 0,15,153:5:0 +X 154 . T <*> 0 . DP=14;I16=12,2,0,0,523,20051,0,0,809,47641,0,0,270,6030,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,159:7:0 0,6,83:2:0 0,15,139:5:0 +X 155 . C <*> 0 . DP=14;I16=12,2,0,0,542,21254,0,0,809,47641,0,0,268,5976,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,172:7:0 0,6,85:2:0 0,15,139:5:0 +X 156 . C <*> 0 . DP=14;I16=12,2,0,0,536,20884,0,0,809,47641,0,0,266,5934,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,163:7:0 0,6,84:2:0 0,15,150:5:0 +X 157 . C <*> 0 . DP=14;I16=12,2,0,0,555,22081,0,0,809,47641,0,0,264,5904,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,169:7:0 0,6,85:2:0 0,15,149:5:0 +X 158 . T <*> 0 . DP=14;I16=12,2,0,0,568,23154,0,0,809,47641,0,0,262,5886,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,170:7:0 0,6,84:2:0 0,15,159:5:0 +X 159 . A <*> 0 . DP=15;I16=12,2,0,0,519,19467,0,0,809,47641,0,0,260,5880,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,157:7:0 0,6,83:2:0 0,15,135:5:0 +X 160 . G <*> 0 . DP=15;I16=13,2,0,0,547,20633,0,0,869,51241,0,0,259,5887,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,165:7:0 0,6,85:2:0 0,18,139:6:0 +X 161 . A <*> 0 . DP=15;I16=13,2,0,0,568,21610,0,0,869,51241,0,0,258,5908,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,157:7:0 0,6,83:2:0 0,18,162:6:0 +X 162 . A <*> 0 . DP=15;I16=13,2,0,0,557,21139,0,0,869,51241,0,0,255,5843,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,147:7:0 0,6,87:2:0 0,18,167:6:0 +X 163 . G <*> 0 . DP=14;I16=12,2,0,0,503,18645,0,0,809,47641,0,0,253,5791,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,153:7:0 0,6,79:2:0 0,15,138:5:0 +X 164 . T <*> 0 . DP=14;I16=12,2,0,0,460,15968,0,0,809,47641,0,0,252,5750,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,131:6:0 0,6,79:2:0 0,18,136:6:0 +X 165 . G <*> 0 . DP=14;I16=10,2,0,0,456,17460,0,0,689,40441,0,0,226,5094,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,149:6:0 0,6,80:2:0 0,12,122:4:0 +X 166 . A <*> 0 . DP=14;I16=11,2,0,0,496,19138,0,0,749,44041,0,0,227,5077,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,145:6:0 0,6,82:2:0 0,15,148:5:0 +X 167 . A <*> 0 . DP=14;I16=11,2,0,0,477,17851,0,0,749,44041,0,0,227,5071,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,132:6:0 0,6,86:2:0 0,15,147:5:0 +X 168 . G <*> 0 . DP=14;I16=12,2,0,0,481,18015,0,0,809,47641,0,0,252,5702,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,145:6:0 0,6,82:2:0 0,18,140:6:0 +X 169 . C <*> 0 . DP=13;I16=10,2,0,0,402,14224,0,0,689,40441,0,0,227,5045,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,15,106:5:0 0,6,76:2:0 0,15,145:5:0 +X 170 . C <*> 0 . DP=13;I16=11,2,0,0,447,16383,0,0,749,44041,0,0,251,5601,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,15,128:5:0 0,6,80:2:0 0,18,143:6:0 +X 171 . A <*> 0 . DP=13;I16=11,2,0,0,500,19366,0,0,749,44041,0,0,250,5546,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,15,134:5:0 0,6,81:2:0 0,18,166:6:0 +X 172 . C <*> 0 . DP=13;I16=10,2,0,0,439,16395,0,0,689,40441,0,0,241,5441,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,15,138:5:0 0,6,75:2:0 0,15,129:5:0 +X 173 . C <*> 0 . DP=13;I16=11,2,0,0,435,15225,0,0,749,44041,0,0,248,5478,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,15,121:5:0 0,6,76:2:0 0,18,146:6:0 +X 174 . G <*> 0 . DP=13;I16=11,1,0,0,351,10685,0,0,689,40441,0,0,238,5364,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,111:5:0 0,3,27:1:0 0,18,117:6:0 +X 175 . C <*> 0 . DP=14;I16=13,1,0,0,511,19161,0,0,809,47641,0,0,249,5463,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,143:6:0 0,3,41:1:0 0,21,175:7:0 +X 176 . C <*> 0 . DP=14;I16=13,1,0,0,489,17733,0,0,809,47641,0,0,251,5477,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,146:6:0 0,3,44:1:0 0,21,152:7:0 +X 177 . C <*> 0 . DP=14;I16=13,1,0,0,488,17328,0,0,809,47641,0,0,253,5507,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,138:6:0 0,3,44:1:0 0,21,158:7:0 +X 178 . A <*> 0 . DP=14;I16=13,1,0,0,519,19485,0,0,809,47641,0,0,254,5502,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,147:6:0 0,3,42:1:0 0,21,172:7:0 +X 179 . A <*> 0 . DP=14;I16=13,1,0,0,478,17278,0,0,809,47641,0,0,255,5511,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,134:6:0 0,3,44:1:0 0,21,170:7:0 +X 180 . A <*> 0 . DP=14;I16=12,1,0,0,425,14653,0,0,749,44041,0,0,250,5498,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,126:6:0 0,3,43:1:0 0,18,148:6:0 +X 181 . G <*> 0 . DP=14;I16=11,1,0,0,450,17152,0,0,689,40441,0,0,233,5233,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,156:6:0 0,3,41:1:0 0,15,138:5:0 +X 182 . A <*> 0 . DP=15;I16=14,1,0,0,515,18235,0,0,869,51241,0,0,258,5622,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,150:7:0 0,3,43:1:0 0,21,159:7:0 +X 183 . C <*> 0 . DP=15;I16=13,1,0,0,483,17419,0,0,809,47641,0,0,235,5063,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,159:7:0 0,3,40:1:0 0,18,139:6:0 +X 184 . A <*> 0 . DP=15;I16=14,1,0,0,535,19667,0,0,869,51241,0,0,262,5770,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,158:7:0 0,3,41:1:0 0,21,163:7:0 +X 185 . C <*> 0 . DP=15;I16=13,1,0,0,487,17295,0,0,809,47641,0,0,238,5192,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,150:7:0 0,3,38:1:0 0,18,160:6:0 +X 186 . G <*> 0 . DP=15;I16=12,1,0,0,381,11429,0,0,749,44041,0,0,239,5253,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,117:6:0 0,3,32:1:0 0,18,124:6:0 +X 187 . C <*> 0 . DP=14;I16=13,1,0,0,511,18979,0,0,809,47641,0,0,266,5952,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,147:6:0 0,3,38:1:0 0,21,172:7:0 +X 188 . C <*> 0 . DP=14;I16=13,1,0,0,496,18042,0,0,809,47641,0,0,267,5989,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,147:6:0 0,3,37:1:0 0,21,162:7:0 +X 189 . C <*> 0 . DP=15;I16=13,2,0,0,552,20504,0,0,838,48482,0,0,268,6040,0,0;QS=3,0;MQSB=0;MQ0F=0 PL:DP:DV 0,18,152:6:0 0,6,67:2:0 0,21,167:7:0 +X 190 . A <*> 0 . DP=15;I16=12,2,0,0,500,18230,0,0,778,44882,0,0,243,5381,0,0;QS=3,0;MQSB=0;MQ0F=0 PL:DP:DV 0,18,138:6:0 0,6,68:2:0 0,18,159:6:0 +X 191 . T <*> 0 . DP=15;I16=13,2,0,0,534,19276,0,0,838,48482,0,0,267,5939,0,0;QS=3,0;MQSB=0;MQ0F=0 PL:DP:DV 0,18,143:6:0 0,6,67:2:0 0,21,169:7:0 +X 192 . G <*> 0 . DP=15;I16=13,2,0,0,499,17439,0,0,838,48482,0,0,266,5890,0,0;QS=3,0;MQSB=0;MQ0F=0 PL:DP:DV 0,18,143:6:0 0,6,67:2:0 0,21,151:7:0 +X 193 . T <*> 0 . DP=15;I16=13,2,0,0,505,17811,0,0,838,48482,0,0,265,5859,0,0;QS=3,0;MQSB=0;MQ0F=0 PL:DP:DV 0,18,140:6:0 0,6,63:2:0 0,21,157:7:0 +X 194 . C <*> 0 . DP=14;I16=12,2,0,0,467,16569,0,0,778,44882,0,0,265,5845,0,0;QS=3,0;MQSB=0;MQ0F=0 PL:DP:DV 0,18,142:6:0 0,6,67:2:0 0,18,145:6:0 +X 195 . C <*> 0 . DP=14;I16=11,3,0,0,503,18647,0,0,747,42123,0,0,266,5846,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,18,159:6:0 0,6,71:2:0 0,18,160:6:0 +X 196 . A <*> 0 . DP=14;I16=11,3,0,0,482,17400,0,0,747,42123,0,0,268,5862,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,18,166:6:0 0,6,69:2:0 0,18,138:6:0 +X 197 . G <*> 0 . DP=14;I16=11,3,0,0,481,17391,0,0,747,42123,0,0,270,5894,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,18,164:6:0 0,6,68:2:0 0,18,134:6:0 +X 198 . C <*> 0 . DP=14;I16=11,3,0,0,539,20957,0,0,747,42123,0,0,271,5893,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,18,172:6:0 0,6,70:2:0 0,18,164:6:0 +X 199 . T <*> 0 . DP=14;I16=11,3,0,0,505,19197,0,0,747,42123,0,0,271,5861,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,18,162:6:0 0,6,73:2:0 0,18,154:6:0 +X 200 . T <*> 0 . DP=15;I16=11,4,0,0,544,19918,0,0,776,42964,0,0,270,5798,0,0;QS=3,0;MQSB=0.0161635;MQ0F=0 PL:DP:DV 0,18,161:6:0 0,9,89:3:0 0,18,154:6:0 +X 201 . A <*> 0 . DP=16;I16=12,4,0,0,568,20416,0,0,836,46564,0,0,269,5703,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,171:7:0 0,9,89:3:0 0,18,157:6:0 +X 202 . A <*> 0 . DP=16;I16=12,4,0,0,566,20590,0,0,836,46564,0,0,269,5627,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,178:7:0 0,9,84:3:0 0,18,163:6:0 +X 203 . C <*> 0 . DP=16;I16=12,4,0,0,557,20119,0,0,836,46564,0,0,269,5571,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,166:7:0 0,9,90:3:0 0,18,153:6:0 +X 204 . C <*> 0 . DP=16;I16=12,4,0,0,591,22379,0,0,836,46564,0,0,269,5535,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,173:7:0 0,9,91:3:0 0,18,163:6:0 +X 205 . T <*> 0 . DP=16;I16=12,4,0,0,635,25281,0,0,836,46564,0,0,269,5519,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,188:7:0 0,9,95:3:0 0,18,173:6:0 +X 206 . G <*> 0 . DP=16;I16=12,4,0,0,577,21337,0,0,836,46564,0,0,269,5523,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,180:7:0 0,9,89:3:0 0,18,143:6:0 +X 207 . C <*> 0 . DP=16;I16=12,4,0,0,574,21076,0,0,836,46564,0,0,269,5547,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,179:7:0 0,9,93:3:0 0,18,151:6:0 +X 208 . A <*> 0 . DP=16;I16=12,4,0,0,576,21486,0,0,836,46564,0,0,268,5540,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,184:7:0 0,9,93:3:0 0,18,154:6:0 +X 209 . T <*> 0 . DP=16;I16=12,4,0,0,567,20475,0,0,836,46564,0,0,267,5551,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,173:7:0 0,9,91:3:0 0,18,146:6:0 +X 210 . C <*> 0 . DP=16;I16=12,4,0,0,577,21109,0,0,836,46564,0,0,266,5580,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,185:7:0 0,9,92:3:0 0,18,151:6:0 +X 211 . C <*> 0 . DP=16;I16=12,4,0,0,563,20227,0,0,836,46564,0,0,265,5627,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,172:7:0 0,9,92:3:0 0,18,153:6:0 +X 212 . C <*> 0 . DP=16;I16=12,4,0,0,589,22179,0,0,836,46564,0,0,263,5643,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,181:7:0 0,9,92:3:0 0,18,152:6:0 +X 213 . T <*> 0 . DP=16;I16=12,4,0,0,598,22838,0,0,836,46564,0,0,262,5678,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,181:7:0 0,9,95:3:0 0,18,165:6:0 +X 214 . A <*> 0 . DP=16;I16=11,4,0,0,529,19401,0,0,776,42964,0,0,240,5248,0,0;QS=3,0;MQSB=0.0161635;MQ0F=0 PL:DP:DV 0,21,176:7:0 0,9,92:3:0 0,15,118:5:0 +X 215 . G <*> 0 . DP=15;I16=12,3,0,0,521,19073,0,0,807,45723,0,0,262,5754,0,0;QS=3,0;MQSB=0.0342181;MQ0F=0 PL:DP:DV 0,21,185:7:0 0,9,90:3:0 0,15,105:5:0 +X 216 . A <*> 0 . DP=14;I16=10,3,0,0,464,16900,0,0,687,38523,0,0,238,5166,0,0;QS=3,0;MQSB=0.040184;MQ0F=0 PL:DP:DV 0,21,173:7:0 0,9,92:3:0 0,9,81:3:0 +X 217 . A <*> 0 . DP=14;I16=11,3,0,0,515,19433,0,0,747,42123,0,0,264,5842,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,21,181:7:0 0,9,90:3:0 0,12,97:4:0 +X 218 . G <*> 0 . DP=14;I16=11,3,0,0,507,18957,0,0,747,42123,0,0,265,5907,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,21,178:7:0 0,9,90:3:0 0,12,110:4:0 +X 219 . T <*> 0 . DP=14;I16=11,3,0,0,470,16286,0,0,747,42123,0,0,266,5986,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,21,173:7:0 0,9,88:3:0 0,12,89:4:0 +X 220 . G <*> 0 . DP=14;I16=10,3,0,0,485,18307,0,0,687,38523,0,0,242,5454,0,0;QS=3,0;MQSB=0.040184;MQ0F=0 PL:DP:DV 0,21,188:7:0 0,9,88:3:0 0,9,80:3:0 +X 221 . A <*> 0 . DP=14;I16=11,3,0,0,487,17615,0,0,747,42123,0,0,267,6135,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,21,176:7:0 0,9,88:3:0 0,12,101:4:0 +X 222 . A <*> 0 . DP=14;I16=10,3,0,0,465,17367,0,0,687,38523,0,0,242,5578,0,0;QS=3,0;MQSB=0.040184;MQ0F=0 PL:DP:DV 0,21,186:7:0 0,9,85:3:0 0,9,69:3:0 +X 223 . G <*> 0 . DP=13;I16=9,3,0,0,405,14327,0,0,627,34923,0,0,243,5657,0,0;QS=3,0;MQSB=0.0443614;MQ0F=0 PL:DP:DV 0,18,168:6:0 0,6,53:2:0 0,12,81:4:0 +X 224 . G <*> 0 . DP=12;I16=9,3,0,0,379,12759,0,0,627,34923,0,0,270,6370,0,0;QS=3,0;MQSB=0.0443614;MQ0F=0 PL:DP:DV 0,18,168:6:0 0,6,50:2:0 0,12,70:4:0 +X 225 . C <*> 0 . DP=12;I16=8,3,0,0,382,13896,0,0,567,31323,0,0,261,6345,0,0;QS=3,0;MQSB=0.0497871;MQ0F=0 PL:DP:DV 0,18,165:6:0 0,6,48:2:0 0,9,83:3:0 +X 226 . A <*> 0 . DP=13;I16=8,3,0,0,381,13669,0,0,567,31323,0,0,248,5894,0,0;QS=3,0;MQSB=0.0497871;MQ0F=0 PL:DP:DV 0,18,166:6:0 0,6,53:2:0 0,9,84:3:0 +X 227 . C <*> 0 . DP=13;I16=8,4,0,0,406,14306,0,0,596,32164,0,0,267,6253,0,0;QS=3,0;MQSB=0.0249144;MQ0F=0 PL:DP:DV 0,21,190:7:0 0,6,53:2:0 0,9,73:3:0 +X 228 . C <*> 0 . DP=13;I16=9,4,0,0,417,14381,0,0,656,35764,0,0,292,6884,0,0;QS=3,0;MQSB=0.0211283;MQ0F=0 PL:DP:DV 0,21,187:7:0 0,6,45:2:0 0,12,96:4:0 +X 229 . G <*> 0 . DP=13;I16=9,3,0,0,358,11424,0,0,627,34923,0,0,270,6414,0,0;QS=3,0;MQSB=0.0443614;MQ0F=0 PL:DP:DV 0,18,136:6:0 0,6,53:2:0 0,12,70:4:0 +X 230 . C <*> 0 . DP=13;I16=9,4,0,0,461,16861,0,0,656,35764,0,0,292,6920,0,0;QS=3,0;MQSB=0.0211283;MQ0F=0 PL:DP:DV 0,21,186:7:0 0,6,53:2:0 0,12,100:4:0 +X 231 . C <*> 0 . DP=13;I16=7,4,0,0,414,15832,0,0,536,28564,0,0,247,5925,0,0;QS=3,0;MQSB=0.0401934;MQ0F=0 PL:DP:DV 0,18,184:6:0 0,6,53:2:0 0,9,82:3:0 +X 232 . C <*> 0 . DP=14;I16=9,4,0,0,471,17371,0,0,656,35764,0,0,267,6363,0,0;QS=3,0;MQSB=0.0211283;MQ0F=0 PL:DP:DV 0,21,198:7:0 0,6,53:2:0 0,12,101:4:0 +X 233 . A <*> 0 . DP=14;I16=10,4,0,0,496,18142,0,0,716,39364,0,0,292,6984,0,0;QS=3,0;MQSB=0.0183156;MQ0F=0 PL:DP:DV 0,21,192:7:0 0,6,53:2:0 0,15,119:5:0 +X 234 . A <*> 0 . DP=14;I16=10,4,0,0,502,18390,0,0,716,39364,0,0,292,6988,0,0;QS=3,0;MQSB=0.0183156;MQ0F=0 PL:DP:DV 0,21,185:7:0 0,6,53:2:0 0,15,123:5:0 +X 235 . A <*> 0 . DP=14;I16=9,4,0,0,476,17652,0,0,656,35764,0,0,267,6375,0,0;QS=3,0;MQSB=0.0211283;MQ0F=0 PL:DP:DV 0,21,186:7:0 0,6,53:2:0 0,12,111:4:0 +X 236 . G <*> 0 . DP=15;I16=11,4,0,0,501,17481,0,0,776,42964,0,0,290,6924,0,0;QS=3,0;MQSB=0.0161635;MQ0F=0 PL:DP:DV 0,24,206:8:0 0,6,53:2:0 0,15,103:5:0 +X 237 . A <*> 0 . DP=14;I16=9,4,0,0,465,16877,0,0,656,35764,0,0,266,6282,0,0;QS=3,0;MQSB=0.0211283;MQ0F=0 PL:DP:DV 0,24,206:8:0 0,6,53:2:0 0,9,92:3:0 +X 238 . C <*> 0 . DP=14;I16=10,4,0,0,482,17238,0,0,716,39364,0,0,292,6900,0,0;QS=3,0;MQSB=0.0183156;MQ0F=0 PL:DP:DV 0,24,211:8:0 0,6,53:2:0 0,12,82:4:0 +X 239 . A <*> 0 . DP=15;I16=10,5,0,0,525,19155,0,0,776,42964,0,0,292,6852,0,0;QS=3,0;MQSB=0.0497871;MQ0F=0 PL:DP:DV 0,27,223:9:0 0,6,50:2:0 0,12,108:4:0 +X 240 . C <*> 0 . DP=15;I16=10,5,0,0,512,17930,0,0,776,42964,0,0,292,6764,0,0;QS=3,0;MQSB=0.0497871;MQ0F=0 PL:DP:DV 0,27,220:9:0 0,6,53:2:0 0,12,106:4:0 +X 241 . G <*> 0 . DP=15;I16=9,5,0,0,444,14636,0,0,716,39364,0,0,269,6159,0,0;QS=3,0;MQSB=0.0561348;MQ0F=0 PL:DP:DV 0,27,203:9:0 0,6,53:2:0 0,9,59:3:0 +X 242 . C <*> 0 . DP=15;I16=10,5,0,0,555,21177,0,0,776,42964,0,0,292,6624,0,0;QS=3,0;MQSB=0.0497871;MQ0F=0 PL:DP:DV 0,27,242:9:0 0,6,53:2:0 0,12,94:4:0 +X 243 . C <*> 0 . DP=16;I16=9,5,0,0,523,19737,0,0,716,39364,0,0,284,6508,0,0;QS=3,0;MQSB=0.0561348;MQ0F=0 PL:DP:DV 0,24,220:8:0 0,6,53:2:0 0,12,104:4:0 +X 244 . C <*> 0 . DP=16;I16=10,6,0,0,620,24272,0,0,805,43805,0,0,298,6568,0,0;QS=3,0;MQSB=0.0253122;MQ0F=0 PL:DP:DV 0,27,245:9:0 0,9,72:3:0 0,12,106:4:0 +X 245 . A <*> 0 . DP=17;I16=10,7,0,0,649,24843,0,0,865,47405,0,0,299,6553,0,0;QS=3,0;MQSB=0.0509867;MQ0F=0 PL:DP:DV 0,27,236:9:0 0,12,93:4:0 0,12,115:4:0 +X 246 . T <*> 0 . DP=18;I16=10,8,0,0,649,23833,0,0,894,48246,0,0,301,6553,0,0;QS=3,0;MQSB=0.0286491;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,12,94:4:0 0,12,98:4:0 +X 247 . G <*> 0 . DP=18;I16=10,8,0,0,642,23610,0,0,894,48246,0,0,304,6570,0,0;QS=3,0;MQSB=0.0286491;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,12,83:4:0 0,12,103:4:0 +X 248 . T <*> 0 . DP=18;I16=10,8,0,0,636,22944,0,0,894,48246,0,0,307,6605,0,0;QS=3,0;MQSB=0.0286491;MQ0F=0 PL:DP:DV 0,30,234:10:0 0,12,86:4:0 0,12,114:4:0 +X 249 . C <*> 0 . DP=18;I16=10,8,0,0,656,24846,0,0,894,48246,0,0,310,6658,0,0;QS=3,0;MQSB=0.0286491;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,12,79:4:0 0,12,112:4:0 +X 250 . C <*> 0 . DP=19;I16=10,9,0,0,694,26160,0,0,923,49087,0,0,311,6631,0,0;QS=3,0;MQSB=0.0168512;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,12,89:4:0 0,15,142:5:0 +X 251 . A <*> 0 . DP=19;I16=9,9,0,0,688,26506,0,0,863,45487,0,0,313,6627,0,0;QS=3,0;MQSB=0.0208913;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,12,97:4:0 0,15,148:5:0 +X 252 . G <*> 0 . DP=18;I16=8,9,0,0,641,24631,0,0,803,41887,0,0,304,6502,0,0;QS=3,0;MQSB=0.026526;MQ0F=0 PL:DP:DV 0,27,243:9:0 0,12,91:4:0 0,12,121:4:0 +X 253 . C <*> 0 . DP=19;I16=9,10,0,0,705,26921,0,0,892,46328,0,0,319,6687,0,0;QS=3,0;MQSB=0.0132999;MQ0F=0 PL:DP:DV 0,27,247:9:0 0,12,86:4:0 0,18,155:6:0 +X 254 . T <*> 0 . DP=20;I16=10,9,0,0,719,27517,0,0,892,46328,0,0,314,6670,0,0;QS=3,0;MQSB=0.00482795;MQ0F=0 PL:DP:DV 0,30,254:10:0 0,9,72:3:0 0,18,164:6:0 +X 255 . T <*> 0 . DP=21;I16=11,10,0,0,750,27076,0,0,1012,53528,0,0,328,6840,0,0;QS=3,0;MQSB=0.00822975;MQ0F=0 PL:DP:DV 0,33,241:11:0 0,12,95:4:0 0,18,161:6:0 +X 256 . A <*> 0 . DP=22;I16=11,11,0,0,811,30063,0,0,1049,54897,0,0,334,6956,0,0;QS=3,0;MQSB=0.00507916;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,110:5:0 0,18,166:6:0 +X 257 . T <*> 0 . DP=22;I16=11,11,0,0,814,30420,0,0,1049,54897,0,0,341,7101,0,0;QS=3,0;MQSB=0.00507916;MQ0F=0 PL:DP:DV 0,33,247:11:0 0,15,113:5:0 0,18,168:6:0 +X 258 . T <*> 0 . DP=22;I16=11,11,0,0,791,28943,0,0,1049,54897,0,0,347,7225,0,0;QS=3,0;MQSB=0.00507916;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,15,116:5:0 0,18,155:6:0 +X 259 . C <*> 0 . DP=22;I16=11,10,0,0,785,29809,0,0,1020,54056,0,0,332,6936,0,0;QS=3,0;MQSB=0.00822975;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,90:4:0 0,18,170:6:0 +X 260 . T <*> 0 . DP=21;I16=10,11,0,0,829,32899,0,0,989,51297,0,0,360,7556,0,0;QS=3,0;MQSB=0.00660016;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,118:5:0 0,15,156:5:0 +X 261 . G <*> 0 . DP=21;I16=10,11,0,0,735,27379,0,0,989,51297,0,0,367,7761,0,0;QS=3,0;MQSB=0.00660016;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,15,111:5:0 0,15,122:5:0 +X 262 . C <*> 0 . DP=22;I16=10,12,0,0,806,30278,0,0,1049,54897,0,0,373,7941,0,0;QS=3,0;MQSB=0.0122507;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,99:5:0 0,18,164:6:0 +X 263 . C <*> 0 . DP=22;I16=10,12,0,0,799,29717,0,0,1049,54897,0,0,380,8146,0,0;QS=3,0;MQSB=0.0122507;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,98:5:0 0,18,168:6:0 +X 264 . C <*> 0 . DP=22;I16=10,12,0,0,821,31325,0,0,1049,54897,0,0,386,8326,0,0;QS=3,0;MQSB=0.0122507;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,104:5:0 0,18,172:6:0 +X 265 . A <*> 0 . DP=21;I16=9,12,0,0,800,31906,0,0,989,51297,0,0,390,8380,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,114:5:0 0,15,129:5:0 +X 266 . G <*> 0 . DP=21;I16=9,11,0,0,747,28155,0,0,960,50456,0,0,369,7833,0,0;QS=3,0;MQSB=0.0237479;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,97:4:0 0,15,138:5:0 +X 267 . T <*> 0 . DP=21;I16=9,11,0,0,739,27465,0,0,960,50456,0,0,373,7935,0,0;QS=3,0;MQSB=0.0237479;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,12,101:4:0 0,15,149:5:0 +X 268 . T <*> 0 . DP=21;I16=9,12,0,0,748,27708,0,0,989,51297,0,0,402,8686,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:DV 0,33,238:11:0 0,15,110:5:0 0,15,156:5:0 +X 269 . C <*> 0 . DP=22;I16=9,12,0,0,764,28632,0,0,989,51297,0,0,381,8211,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,91:4:0 0,15,154:5:0 +X 270 . C <*> 0 . DP=22;I16=9,12,0,0,758,28146,0,0,989,51297,0,0,385,8337,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,96:4:0 0,15,143:5:0 +X 271 . T <*> 0 . DP=22;I16=9,13,0,0,847,32935,0,0,1018,52138,0,0,413,9065,0,0;QS=3,0;MQSB=0.0109431;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,113:5:0 0,15,152:5:0 +X 272 . C <*> 0 . DP=22;I16=9,12,0,0,809,31413,0,0,989,51297,0,0,390,8518,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,96:4:0 0,15,149:5:0 +X 273 . T <*> 0 . DP=22;I16=9,12,0,0,798,30664,0,0,989,51297,0,0,392,8620,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,95:4:0 0,15,161:5:0 +X 274 . C <*> 0 . DP=22;I16=9,12,0,0,763,28177,0,0,989,51297,0,0,394,8746,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,101:4:0 0,15,144:5:0 +X 275 . C <*> 0 . DP=20;I16=7,13,0,0,768,29994,0,0,898,44938,0,0,423,9519,0,0;QS=3,0;MQSB=0.0213617;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,114:5:0 0,12,122:4:0 +X 276 . A <*> 0 . DP=20;I16=7,13,0,0,805,32931,0,0,898,44938,0,0,424,9538,0,0;QS=3,0;MQSB=0.0213617;MQ0F=0 PL:DP:DV 0,33,253:11:0 0,15,122:5:0 0,12,124:4:0 +X 277 . G <*> 0 . DP=20;I16=7,13,0,0,764,29732,0,0,898,44938,0,0,425,9579,0,0;QS=3,0;MQSB=0.0213617;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,114:5:0 0,12,121:4:0 +X 278 . A <*> 0 . DP=21;I16=6,14,0,0,722,26452,0,0,867,42179,0,0,415,9521,0,0;QS=3,0;MQSB=0.0246228;MQ0F=0 PL:DP:DV 0,30,238:10:0 0,18,123:6:0 0,12,121:4:0 +X 279 . A <*> 0 . DP=22;I16=7,15,0,0,786,28694,0,0,956,46620,0,0,427,9677,0,0;QS=3,0;MQSB=0.0124927;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,123:6:0 0,12,122:4:0 +X 280 . A <*> 0 . DP=22;I16=7,15,0,0,815,31561,0,0,956,46620,0,0,428,9684,0,0;QS=3,0;MQSB=0.0124927;MQ0F=0 PL:DP:DV 0,36,253:12:0 0,18,130:6:0 0,12,129:4:0 +X 281 . G <*> 0 . DP=22;I16=7,15,0,0,820,31416,0,0,956,46620,0,0,428,9662,0,0;QS=3,0;MQSB=0.0124927;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,122:6:0 0,12,123:4:0 +X 282 . G <*> 0 . DP=22;I16=7,15,0,0,806,30420,0,0,956,46620,0,0,427,9609,0,0;QS=3,0;MQSB=0.0124927;MQ0F=0 PL:DP:DV 0,36,253:12:0 0,18,124:6:0 0,12,119:4:0 +X 283 . C <*> 0 . DP=23;I16=7,15,0,0,827,31785,0,0,956,46620,0,0,426,9574,0,0;QS=3,0;MQSB=0.0124927;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,125:6:0 0,12,122:4:0 +X 284 . T <*> 0 . DP=23;I16=7,16,0,0,901,35479,0,0,1016,50220,0,0,431,9593,0,0;QS=3,0;MQSB=0.0194969;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,126:6:0 0,15,144:5:0 +X 285 . G <*> 0 . DP=23;I16=7,16,0,0,860,32856,0,0,1016,50220,0,0,431,9607,0,0;QS=3,0;MQSB=0.0194969;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,119:6:0 0,15,132:5:0 +X 286 . C <*> 0 . DP=24;I16=8,16,0,0,875,32883,0,0,1076,53820,0,0,431,9641,0,0;QS=3,0;MQSB=0.0132999;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,150:7:0 0,15,134:5:0 +X 287 . A <*> 0 . DP=25;I16=9,16,0,0,895,32957,0,0,1136,57420,0,0,432,9696,0,0;QS=3,0;MQSB=0.00934348;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,178:8:0 0,15,133:5:0 +X 288 . T <*> 0 . DP=25;I16=9,16,0,0,931,35011,0,0,1136,57420,0,0,432,9674,0,0;QS=3,0;MQSB=0.00934348;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,184:8:0 0,15,146:5:0 +X 289 . G <*> 0 . DP=25;I16=9,16,0,0,939,36117,0,0,1136,57420,0,0,432,9676,0,0;QS=3,0;MQSB=0.00934348;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,185:8:0 0,15,136:5:0 +X 290 . G <*> 0 . DP=23;I16=8,15,0,0,805,29157,0,0,1047,52979,0,0,433,9651,0,0;QS=3,0;MQSB=0.0177152;MQ0F=0 PL:DP:DV 0,33,240:11:0 0,21,164:7:0 0,15,126:5:0 +X 291 . T <*> 0 . DP=24;I16=8,15,0,0,840,31616,0,0,1047,52979,0,0,421,9479,0,0;QS=3,0;MQSB=0.0177152;MQ0F=0 PL:DP:DV 0,33,244:11:0 0,21,168:7:0 0,15,136:5:0 +X 292 . T <*> 0 . DP=25;I16=9,16,0,0,888,32274,0,0,1167,60179,0,0,436,9668,0,0;QS=3,0;MQSB=0.0197089;MQ0F=0 PL:DP:DV 0,33,253:11:0 0,24,181:8:0 0,18,156:6:0 +X 293 . G <*> 0 . DP=26;I16=10,15,0,0,934,35232,0,0,1167,60179,0,0,424,9488,0,0;QS=3,0;MQSB=0.0095249;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,196:8:0 0,15,145:5:0 +X 294 . A <*> 0 . DP=26;I16=10,16,0,0,931,33937,0,0,1227,63779,0,0,443,9785,0,0;QS=3,0;MQSB=0.0149748;MQ0F=0 PL:DP:DV 0,36,252:12:0 0,24,201:8:0 0,18,161:6:0 +X 295 . C <*> 0 . DP=25;I16=10,14,0,0,897,33973,0,0,1169,62097,0,0,430,9544,0,0;QS=3,0;MQSB=0.0310726;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,180:7:0 0,18,159:6:0 +X 296 . A <*> 0 . DP=25;I16=10,15,0,0,874,31846,0,0,1198,62938,0,0,451,9905,0,0;QS=3,0;MQSB=0.0213617;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,169:8:0 0,18,169:6:0 +X 297 . C <*> 0 . DP=25;I16=9,15,0,0,901,34305,0,0,1138,59338,0,0,445,9901,0,0;QS=3,0;MQSB=0.0273237;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,174:7:0 0,18,161:6:0 +X 298 . A <*> 0 . DP=26;I16=11,15,0,0,936,34652,0,0,1258,66538,0,0,459,10121,0,0;QS=3,0;MQSB=0.017008;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,184:8:0 0,21,191:7:0 +X 299 . C <*> 0 . DP=27;I16=11,15,0,0,971,36863,0,0,1258,66538,0,0,464,10266,0,0;QS=3,0;MQSB=0.017008;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,193:8:0 0,21,189:7:0 +X 300 . A <*> 0 . DP=27;I16=11,15,0,0,1001,39455,0,0,1258,66538,0,0,469,10437,0,0;QS=3,0;MQSB=0.017008;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,204:8:0 0,21,210:7:0 +X 301 . G <*> 0 . DP=25;I16=10,14,0,0,928,36116,0,0,1169,62097,0,0,476,10632,0,0;QS=3,0;MQSB=0.0310726;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,195:7:0 0,21,196:7:0 +X 302 . T <*> 0 . DP=25;I16=10,14,0,0,879,32885,0,0,1169,62097,0,0,483,10849,0,0;QS=3,0;MQSB=0.0310726;MQ0F=0 PL:DP:DV 0,30,231:10:0 0,21,172:7:0 0,21,202:7:0 +X 302 . T TA 0 . INDEL;IDV=7;IMF=1;DP=25;I16=2,4,8,11,214,7674,793,33369,236,10564,993,55133,109,2229,377,8629;QS=0.511212,2.48879;VDB=0.27613;SGB=-4.22417;MQSB=0.0443614;MQ0F=0 PL:DP:DV 167,0,96:11:6 157,0,9:7:6 201,21,0:7:7 +X 303 . G <*> 0 . DP=25;I16=10,15,0,0,976,38516,0,0,1229,65697,0,0,497,11181,0,0;QS=3,0;MQSB=0.0443614;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,197:7:0 0,21,195:7:0 +X 304 . C <*> 0 . DP=27;I16=11,16,0,0,991,37005,0,0,1318,70138,0,0,503,11359,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,206:8:0 0,24,200:8:0 +X 305 . C <*> 0 . DP=27;I16=11,16,0,0,1057,41761,0,0,1318,70138,0,0,510,11508,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,213:8:0 0,24,211:8:0 +X 306 . T <*> 0 . DP=27;I16=11,16,0,0,1033,40253,0,0,1318,70138,0,0,517,11679,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,207:8:0 0,24,217:8:0 +X 307 . G <*> 0 . DP=27;I16=11,15,0,0,984,37886,0,0,1289,69297,0,0,498,11198,0,0;QS=3,0;MQSB=0.174566;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,189:7:0 0,24,203:8:0 +X 308 . C <*> 0 . DP=27;I16=11,16,0,0,892,30810,0,0,1318,70138,0,0,529,11991,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,178:8:0 0,24,185:8:0 +X 309 . G <*> 0 . DP=27;I16=11,16,0,0,951,34599,0,0,1318,70138,0,0,535,12183,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:DV 0,33,243:11:0 0,24,183:8:0 0,24,205:8:0 +X 310 . A <*> 0 . DP=27;I16=11,16,0,0,1001,38063,0,0,1318,70138,0,0,540,12350,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,200:8:0 0,24,217:8:0 +X 311 . C <*> 0 . DP=27;I16=11,16,0,0,1037,40263,0,0,1318,70138,0,0,544,12492,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,215:8:0 0,24,210:8:0 +X 312 . A <*> 0 . DP=26;I16=10,16,0,0,985,38043,0,0,1258,66538,0,0,549,12657,0,0;QS=3,0;MQSB=0.157183;MQ0F=0 PL:DP:DV 0,30,237:10:0 0,24,215:8:0 0,24,218:8:0 +X 313 . A <*> 0 . DP=26;I16=10,16,0,0,983,37969,0,0,1258,66538,0,0,551,12695,0,0;QS=3,0;MQSB=0.157183;MQ0F=0 PL:DP:DV 0,30,235:10:0 0,24,219:8:0 0,24,215:8:0 +X 314 . A <*> 0 . DP=27;I16=10,17,0,0,1050,41798,0,0,1318,70138,0,0,553,12757,0,0;QS=3,0;MQSB=0.195223;MQ0F=0 PL:DP:DV 0,33,250:11:0 0,24,217:8:0 0,24,227:8:0 +X 315 . G <*> 0 . DP=26;I16=10,16,0,0,1025,40941,0,0,1289,69297,0,0,557,12843,0,0;QS=3,0;MQSB=0.252051;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,24,216:8:0 0,24,225:8:0 +X 316 . C <*> 0 . DP=27;I16=10,15,0,0,983,39393,0,0,1252,67928,0,0,535,12277,0,0;QS=3,0;MQSB=0.312403;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,183:7:0 0,24,224:8:0 +X 317 . T <*> 0 . DP=27;I16=10,16,0,0,1028,41392,0,0,1320,72056,0,0,547,12557,0,0;QS=3,0;MQSB=0.377061;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,230:8:0 0,24,206:8:0 +X 318 . G <*> 0 . DP=27;I16=10,17,0,0,1038,40546,0,0,1349,72897,0,0,570,13018,0,0;QS=3,0;MQSB=0.297797;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,27,235:9:0 0,24,208:8:0 +X 319 . A <*> 0 . DP=27;I16=9,17,0,0,994,38654,0,0,1289,69297,0,0,560,12906,0,0;QS=3,0;MQSB=0.346864;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,27,228:9:0 0,21,185:7:0 +X 320 . A <*> 0 . DP=27;I16=10,17,0,0,1022,39418,0,0,1349,72897,0,0,573,13053,0,0;QS=3,0;MQSB=0.297797;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,27,230:9:0 0,24,211:8:0 +X 321 . T <*> 0 . DP=27;I16=10,17,0,0,1026,39772,0,0,1349,72897,0,0,573,13029,0,0;QS=3,0;MQSB=0.297797;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,27,214:9:0 0,24,218:8:0 +X 322 . G <*> 0 . DP=28;I16=10,18,0,0,1091,43151,0,0,1409,76497,0,0,573,13029,0,0;QS=3,0;MQSB=0.343265;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,27,226:9:0 0,27,223:9:0 +X 323 . C <*> 0 . DP=28;I16=9,18,0,0,1067,42619,0,0,1349,72897,0,0,565,12939,0,0;QS=3,0;MQSB=0.394987;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,27,225:9:0 0,24,198:8:0 +X 324 . T <*> 0 . DP=30;I16=12,18,0,0,1145,44221,0,0,1529,83697,0,0,573,13001,0,0;QS=3,0;MQSB=0.264959;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,27,237:9:0 0,33,255:11:0 +X 325 . A <*> 0 . DP=31;I16=13,18,0,0,1132,42058,0,0,1589,87297,0,0,573,12925,0,0;QS=3,0;MQSB=0.235201;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,208:9:0 0,33,255:11:0 +X 326 . T <*> 0 . DP=31;I16=13,18,0,0,1157,44193,0,0,1589,87297,0,0,574,12878,0,0;QS=3,0;MQSB=0.235201;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,216:9:0 0,33,255:11:0 +X 327 . C <*> 0 . DP=31;I16=13,18,0,0,1147,43895,0,0,1589,87297,0,0,575,12861,0,0;QS=3,0;MQSB=0.235201;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,198:9:0 0,33,255:11:0 +X 328 . A <*> 0 . DP=31;I16=13,18,0,0,1167,44531,0,0,1589,87297,0,0,574,12776,0,0;QS=3,0;MQSB=0.235201;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,226:9:0 0,33,255:11:0 +X 329 . T <*> 0 . DP=31;I16=13,18,0,0,1210,47742,0,0,1589,87297,0,0,572,12676,0,0;QS=3,0;MQSB=0.235201;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,237:9:0 0,33,255:11:0 +X 330 . T <*> 0 . DP=31;I16=13,18,0,0,1185,45839,0,0,1589,87297,0,0,568,12510,0,0;QS=3,0;MQSB=0.235201;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,27,231:9:0 0,33,255:11:0 +X 331 . T <*> 0 . DP=32;I16=14,18,0,0,1154,42510,0,0,1649,90897,0,0,563,12327,0,0;QS=3,0;MQSB=0.210122;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,222:9:0 0,36,255:12:0 +X 332 . A <*> 0 . DP=32;I16=14,18,0,0,1156,42666,0,0,1649,90897,0,0,560,12178,0,0;QS=3,0;MQSB=0.210122;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,214:9:0 0,33,255:11:0 +X 333 . A <*> 0 . DP=32;I16=14,18,0,0,1141,41987,0,0,1649,90897,0,0,558,12064,0,0;QS=3,0;MQSB=0.210122;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,223:9:0 0,33,255:11:0 +X 334 . A <*> 0 . DP=32;I16=14,18,0,0,1162,43328,0,0,1649,90897,0,0,556,11986,0,0;QS=3,0;MQSB=0.210122;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,221:9:0 0,33,255:11:0 +X 335 . A <*> 0 . DP=32;I16=12,18,0,0,1077,40287,0,0,1529,83697,0,0,552,11934,0,0;QS=3,0;MQSB=0.264959;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,27,219:9:0 0,33,251:11:0 +X 336 . A <*> 0 . DP=32;I16=14,17,0,0,1088,39758,0,0,1612,89528,0,0,536,11574,0,0;QS=3,0;MQSB=0.274662;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,211:8:0 0,36,255:12:0 +X 337 . C <*> 0 . DP=32;I16=13,17,0,0,1115,42381,0,0,1552,85928,0,0,531,11565,0,0;QS=3,0;MQSB=0.301511;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,202:8:0 0,36,255:12:0 +X 338 . T <*> 0 . DP=30;I16=14,16,0,0,1191,47979,0,0,1560,86456,0,0,554,11878,0,0;QS=3,0;MQSB=0.242376;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,226:8:0 0,36,255:12:0 +X 339 . C <*> 0 . DP=31;I16=14,17,0,0,1130,43210,0,0,1589,87297,0,0,554,11874,0,0;QS=3,0;MQSB=0.175471;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,185:8:0 0,36,255:12:0 +X 340 . C <*> 0 . DP=31;I16=14,17,0,0,1196,47044,0,0,1589,87297,0,0,554,11852,0,0;QS=3,0;MQSB=0.175471;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,221:8:0 0,36,255:12:0 +X 341 . T <*> 0 . DP=31;I16=14,17,0,0,1227,48995,0,0,1589,87297,0,0,554,11862,0,0;QS=3,0;MQSB=0.175471;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,216:8:0 0,36,255:12:0 +X 342 . T <*> 0 . DP=31;I16=14,17,0,0,1162,43942,0,0,1589,87297,0,0,554,11904,0,0;QS=3,0;MQSB=0.175471;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,210:8:0 0,36,255:12:0 +X 343 . G <*> 0 . DP=32;I16=14,17,0,0,1150,43702,0,0,1620,90056,0,0,550,11962,0,0;QS=3,0;MQSB=0.283511;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,27,218:9:0 0,36,255:12:0 +X 344 . C <*> 0 . DP=32;I16=14,18,0,0,1181,45169,0,0,1649,90897,0,0,554,12036,0,0;QS=3,0;MQSB=0.210122;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,217:9:0 0,36,255:12:0 +X 345 . T <*> 0 . DP=31;I16=14,17,0,0,1205,47259,0,0,1589,87297,0,0,555,12129,0,0;QS=3,0;MQSB=0.175471;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,221:8:0 0,36,255:12:0 +X 346 . G <*> 0 . DP=31;I16=15,16,0,0,1147,43597,0,0,1620,90056,0,0,557,12255,0,0;QS=3,0;MQSB=0.220358;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,212:8:0 0,36,255:12:0 +X 347 . G <*> 0 . DP=31;I16=14,16,0,0,1119,42227,0,0,1560,86456,0,0,545,12189,0,0;QS=3,0;MQSB=0.242376;MQ0F=0 PL:DP:DV 0,30,251:10:0 0,24,207:8:0 0,36,255:12:0 +X 348 . T <*> 0 . DP=32;I16=15,16,0,0,1145,43007,0,0,1620,90056,0,0,546,12300,0,0;QS=3,0;MQSB=0.220358;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,27,228:9:0 0,36,255:12:0 +X 349 . T <*> 0 . DP=32;I16=16,16,0,0,1194,45350,0,0,1680,93656,0,0,565,12731,0,0;QS=3,0;MQSB=0.201402;MQ0F=0 PL:DP:DV 0,33,246:11:0 0,27,230:9:0 0,36,255:12:0 +X 350 . T <*> 0 . DP=31;I16=16,15,0,0,1142,43072,0,0,1651,92815,0,0,567,12837,0,0;QS=3,0;MQSB=0.286505;MQ0F=0 PL:DP:DV 0,33,249:11:0 0,27,230:9:0 0,33,255:11:0 +X 351 . G <*> 0 . DP=31;I16=16,15,0,0,1146,43750,0,0,1651,92815,0,0,568,12920,0,0;QS=3,0;MQSB=0.286505;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,212:9:0 0,33,255:11:0 +X 352 . A <*> 0 . DP=31;I16=16,14,0,0,1150,45520,0,0,1591,89215,0,0,544,12404,0,0;QS=3,0;MQSB=0.242376;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,224:8:0 0,33,255:11:0 +X 353 . G <*> 0 . DP=29;I16=15,14,0,0,1109,43095,0,0,1562,88374,0,0,570,13064,0,0;QS=3,0;MQSB=0.424373;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,27,231:9:0 0,30,255:10:0 +X 354 . A <*> 0 . DP=28;I16=14,14,0,0,1078,42938,0,0,1502,84774,0,0,571,13075,0,0;QS=3,0;MQSB=0.450096;MQ0F=0 PL:DP:DV 0,27,225:9:0 0,27,244:9:0 0,30,255:10:0 +X 355 . G T,<*> 0 . DP=28;I16=14,13,0,1,1001,37907,41,1681,1442,81174,60,3600,547,12487,25,625;QS=2.875,0.125,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.450096;BQB=1;MQ0F=0 PL:DP:DV 14,0,200,38,203,231:9:1 0,27,222,27,222,222:9:0 0,30,255,30,255,255:10:0 +X 356 . G <*> 0 . DP=27;I16=14,13,0,0,993,37481,0,0,1465,83405,0,0,574,13174,0,0;QS=3,0;MQSB=0.580277;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,24,201:8:0 0,30,255:10:0 +X 357 . C <*> 0 . DP=28;I16=14,13,0,0,1021,39471,0,0,1465,83405,0,0,550,12584,0,0;QS=3,0;MQSB=0.580277;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,205:8:0 0,27,251:9:0 +X 358 . A <*> 0 . DP=28;I16=15,13,0,0,1050,40518,0,0,1525,87005,0,0,576,13216,0,0;QS=3,0;MQSB=0.556581;MQ0F=0 PL:DP:DV 0,30,254:10:0 0,24,197:8:0 0,30,255:10:0 +X 359 . G <*> 0 . DP=29;I16=15,13,0,0,1085,42761,0,0,1525,87005,0,0,552,12620,0,0;QS=3,0;MQSB=0.556581;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,187:7:0 0,33,255:11:0 +X 360 . A <*> 0 . DP=29;I16=15,14,0,0,1111,43259,0,0,1585,90605,0,0,579,13297,0,0;QS=3,0;MQSB=0.604224;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,24,220:8:0 0,33,255:11:0 +X 361 . A <*> 0 . DP=29;I16=15,14,0,0,1116,43442,0,0,1585,90605,0,0,579,13273,0,0;QS=3,0;MQSB=0.604224;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,24,219:8:0 0,33,255:11:0 +X 362 . A <*> 0 . DP=29;I16=16,13,0,0,1104,42700,0,0,1585,90605,0,0,580,13272,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,218:8:0 0,30,255:10:0 +X 363 . A <*> 0 . DP=29;I16=16,13,0,0,1087,41437,0,0,1585,90605,0,0,581,13245,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,213:8:0 0,30,255:10:0 +X 364 . T <*> 0 . DP=29;I16=16,13,0,0,1032,37960,0,0,1585,90605,0,0,582,13244,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:DV 0,33,250:11:0 0,24,205:8:0 0,30,255:10:0 +X 365 . G <*> 0 . DP=29;I16=16,13,0,0,1105,43079,0,0,1585,90605,0,0,582,13218,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,211:8:0 0,30,255:10:0 +X 366 . A <*> 0 . DP=29;I16=16,13,0,0,1090,41562,0,0,1585,90605,0,0,581,13167,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,211:8:0 0,30,255:10:0 +X 367 . T <*> 0 . DP=29;I16=16,13,0,0,1055,39149,0,0,1585,90605,0,0,579,13093,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,204:8:0 0,30,255:10:0 +X 368 . A <*> 0 . DP=29;I16=16,13,0,0,1054,39632,0,0,1585,90605,0,0,576,12998,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,208:8:0 0,30,255:10:0 +X 369 . T <*> 0 . DP=28;I16=16,11,0,0,1037,40275,0,0,1496,86164,0,0,548,12256,0,0;QS=3,0;MQSB=0.659218;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,21,196:7:0 0,30,255:10:0 +X 370 . C <*> 0 . DP=28;I16=16,12,0,0,1045,40219,0,0,1556,89764,0,0,570,12790,0,0;QS=3,0;MQSB=0.705296;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,201:8:0 0,30,255:10:0 +X 371 . T <*> 0 . DP=29;I16=16,13,0,0,1155,46591,0,0,1616,93364,0,0,567,12725,0,0;QS=3,0;MQSB=0.744925;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,227:8:0 0,33,255:11:0 +X 372 . C <*> 0 . DP=30;I16=16,14,0,0,1139,44019,0,0,1676,96964,0,0,564,12636,0,0;QS=3,0;MQSB=0.779025;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,215:8:0 0,33,255:11:0 +X 373 . A <*> 0 . DP=30;I16=16,14,0,0,1142,44118,0,0,1676,96964,0,0,561,12525,0,0;QS=3,0;MQSB=0.779025;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,220:8:0 0,33,255:11:0 +X 374 . T <*> 0 . DP=30;I16=16,14,0,0,1098,41180,0,0,1676,96964,0,0,556,12344,0,0;QS=3,0;MQSB=0.779025;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,221:8:0 0,33,255:11:0 +X 375 . A T,<*> 0 . DP=31;I16=17,13,0,1,1138,43798,14,196,1676,96964,60,3600,547,12177,4,16;QS=2.9661,0.0338983,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.763662;BQB=1;MQ0F=0 PL:DP:DV 0,36,255,36,255,255:12:0 0,24,218,24,218,218:8:0 0,18,255,30,255,255:11:1 +X 376 . G <*> 0 . DP=31;I16=17,14,0,0,1131,42581,0,0,1736,100564,0,0,547,12073,0,0;QS=3,0;MQSB=0.763662;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,220:8:0 0,33,255:11:0 +X 377 . T <*> 0 . DP=31;I16=16,14,0,0,1105,41629,0,0,1676,96964,0,0,518,11360,0,0;QS=3,0;MQSB=0.779025;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,211:8:0 0,33,255:11:0 +X 378 . T <*> 0 . DP=30;I16=18,12,0,0,1098,41066,0,0,1707,99723,0,0,541,11927,0,0;QS=3,0;MQSB=0.878946;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,186:7:0 0,30,255:10:0 +X 379 . G <*> 0 . DP=29;I16=18,10,0,0,1053,40181,0,0,1618,95282,0,0,534,11848,0,0;QS=3,0;MQSB=0.981777;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,187:7:0 0,30,255:10:0 +X 380 . C <*> 0 . DP=29;I16=18,10,0,0,1087,42743,0,0,1618,95282,0,0,514,11172,0,0;QS=3,0;MQSB=0.981777;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,177:6:0 0,30,255:10:0 +X 381 . T <*> 0 . DP=29;I16=18,11,0,0,1168,47412,0,0,1678,98882,0,0,537,11729,0,0;QS=3,0;MQSB=0.987702;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,212:7:0 0,30,255:10:0 +X 382 . T <*> 0 . DP=29;I16=17,11,0,0,1054,40450,0,0,1618,95282,0,0,510,11068,0,0;QS=3,0;MQSB=0.990092;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,182:7:0 0,30,255:10:0 +X 383 . T <*> 0 . DP=29;I16=18,10,0,0,1052,39798,0,0,1618,95282,0,0,507,11013,0,0;QS=3,0;MQSB=0.981777;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,165:6:0 0,30,255:10:0 +X 384 . A <*> 0 . DP=31;I16=19,11,0,0,1077,39885,0,0,1738,102482,0,0,504,10988,0,0;QS=3,0;MQSB=0.985292;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,176:7:0 0,30,255:10:0 +X 385 . C <*> 0 . DP=31;I16=19,12,0,0,1118,41180,0,0,1798,106082,0,0,527,11569,0,0;QS=3,0;MQSB=0.989977;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,186:8:0 0,30,255:10:0 +X 386 . T <*> 0 . DP=30;I16=18,12,0,0,1158,45592,0,0,1738,102482,0,0,526,11556,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,191:7:0 0,30,255:10:0 +X 387 . T <*> 0 . DP=30;I16=18,12,0,0,1105,41821,0,0,1738,102482,0,0,525,11573,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,187:7:0 0,30,255:10:0 +X 388 . T <*> 0 . DP=29;I16=17,12,0,0,1089,41577,0,0,1678,98882,0,0,523,11519,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,180:6:0 0,30,255:10:0 +X 389 . G <*> 0 . DP=29;I16=17,12,0,0,1067,40095,0,0,1678,98882,0,0,520,11444,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,171:6:0 0,30,255:10:0 +X 390 . C <*> 0 . DP=29;I16=17,12,0,0,1071,40423,0,0,1678,98882,0,0,517,11399,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,162:6:0 0,30,255:10:0 +X 391 . A <*> 0 . DP=29;I16=18,11,0,0,1091,41603,0,0,1647,96123,0,0,515,11383,0,0;QS=3,0;MQSB=0.995968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,163:6:0 0,30,255:10:0 +X 392 . T <*> 0 . DP=29;I16=18,11,0,0,1046,38838,0,0,1647,96123,0,0,515,11395,0,0;QS=3,0;MQSB=0.995968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,153:5:0 0,33,255:11:0 +X 393 . A <*> 0 . DP=28;I16=17,11,0,0,1014,37582,0,0,1587,92523,0,0,517,11435,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,133:5:0 0,33,255:11:0 +X 394 . T <*> 0 . DP=28;I16=17,11,0,0,1022,38342,0,0,1587,92523,0,0,519,11503,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,141:5:0 0,33,255:11:0 +X 395 . T <*> 0 . DP=28;I16=17,11,0,0,1060,40596,0,0,1587,92523,0,0,521,11599,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,164:5:0 0,33,255:11:0 +X 396 . T <*> 0 . DP=28;I16=17,11,0,0,1032,39228,0,0,1587,92523,0,0,523,11723,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,158:5:0 0,33,255:11:0 +X 397 . T <*> 0 . DP=28;I16=17,11,0,0,1046,39510,0,0,1587,92523,0,0,524,11824,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,149:5:0 0,33,255:11:0 +X 398 . A <*> 0 . DP=28;I16=17,11,0,0,1021,38105,0,0,1587,92523,0,0,524,11850,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,144:5:0 0,30,255:10:0 +X 399 . A <*> 0 . DP=28;I16=17,11,0,0,1015,38469,0,0,1587,92523,0,0,526,11900,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,140:5:0 0,30,255:10:0 +X 400 . A <*> 0 . DP=29;I16=17,12,0,0,1056,39702,0,0,1647,96123,0,0,526,11828,0,0;QS=3,0;MQSB=0.988062;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,159:5:0 0,33,255:11:0 +X 401 . A <*> 0 . DP=29;I16=17,11,0,0,1052,40302,0,0,1587,92523,0,0,501,11113,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,160:5:0 0,30,255:10:0 +X 402 . T <*> 0 . DP=29;I16=17,12,0,0,1082,41232,0,0,1647,96123,0,0,526,11680,0,0;QS=3,0;MQSB=0.988062;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,149:5:0 0,33,255:11:0 +X 403 . T <*> 0 . DP=29;I16=17,12,0,0,1085,40985,0,0,1647,96123,0,0,526,11654,0,0;QS=3,0;MQSB=0.988062;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,148:5:0 0,33,255:11:0 +X 404 . G <*> 0 . DP=29;I16=17,12,0,0,1074,40524,0,0,1647,96123,0,0,525,11609,0,0;QS=3,0;MQSB=0.988062;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,131:5:0 0,33,255:11:0 +X 405 . T <*> 0 . DP=27;I16=16,10,0,0,988,37870,0,0,1498,88082,0,0,519,11543,0,0;QS=3,0;MQSB=0.987578;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,103:3:0 0,30,255:10:0 +X 406 . G <*> 0 . DP=27;I16=16,11,0,0,976,36752,0,0,1558,91682,0,0,527,11601,0,0;QS=3,0;MQSB=0.992419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,125:4:0 0,30,247:10:0 +X 407 . A <*> 0 . DP=27;I16=16,11,0,0,1007,38355,0,0,1558,91682,0,0,526,11538,0,0;QS=3,0;MQSB=0.992419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,125:4:0 0,30,255:10:0 +X 408 . C <*> 0 . DP=28;I16=16,11,0,0,1006,38136,0,0,1558,91682,0,0,521,11489,0,0;QS=3,0;MQSB=0.992419;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,110:3:0 0,30,244:10:0 +X 409 . T <*> 0 . DP=29;I16=17,12,0,0,1100,42734,0,0,1678,98882,0,0,525,11503,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,131:4:0 0,33,255:11:0 +X 410 . T <*> 0 . DP=29;I16=17,12,0,0,1035,38325,0,0,1678,98882,0,0,524,11432,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,125:4:0 0,33,255:11:0 +X 411 . T <*> 0 . DP=29;I16=17,10,0,0,1003,37747,0,0,1558,91682,0,0,496,10716,0,0;QS=3,0;MQSB=0.984677;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,104:3:0 0,30,255:10:0 +X 412 . C T,<*> 0 . DP=30;I16=17,12,1,0,1094,42458,14,196,1678,98882,60,3600,495,10659,25,625;QS=2.97455,0.0254545,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.991968;BQB=1;MQ0F=0 PL:DP:DV 0,30,255,42,255,255:15:1 0,12,124,12,124,124:4:0 0,33,255,33,255,255:11:0 +X 413 . A <*> 0 . DP=31;I16=18,13,0,0,1189,45985,0,0,1798,106082,0,0,520,11258,0,0;QS=3,0;MQSB=0.995005;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,102:3:0 0,33,255:11:0 +X 414 . T <*> 0 . DP=30;I16=18,12,0,0,1151,44355,0,0,1738,102482,0,0,523,11265,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,109:3:0 0,33,255:11:0 +X 415 . G <*> 0 . DP=30;I16=18,12,0,0,1131,43175,0,0,1738,102482,0,0,526,11306,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,110:3:0 0,33,255:11:0 +X 416 . G <*> 0 . DP=30;I16=17,12,0,0,1083,41273,0,0,1678,98882,0,0,514,11156,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,114:3:0 0,30,253:10:0 +X 417 . C <*> 0 . DP=30;I16=18,12,0,0,1114,42244,0,0,1738,102482,0,0,531,11439,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,108:3:0 0,33,255:11:0 +X 418 . A <*> 0 . DP=30;I16=18,12,0,0,1146,44248,0,0,1738,102482,0,0,532,11478,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,111:3:0 0,33,255:11:0 +X 419 . T <*> 0 . DP=30;I16=18,12,0,0,1117,42327,0,0,1738,102482,0,0,532,11498,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,112:3:0 0,33,255:11:0 +X 420 . A <*> 0 . DP=31;I16=18,13,0,0,1117,41011,0,0,1798,106082,0,0,532,11550,0,0;QS=3,0;MQSB=0.995005;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,108:3:0 0,36,255:12:0 +X 421 . A <*> 0 . DP=33;I16=19,14,0,0,1208,45398,0,0,1887,110523,0,0,533,11635,0,0;QS=3,0;MQSB=0.986656;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,113:3:0 0,42,255:14:0 +X 422 . A <*> 0 . DP=33;I16=19,13,0,0,1205,46441,0,0,1827,106923,0,0,510,11082,0,0;QS=3,0;MQSB=0.991023;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,116:3:0 0,39,255:13:0 +X 423 . T <*> 0 . DP=32;I16=19,13,0,0,1202,45416,0,0,1827,106923,0,0,538,11818,0,0;QS=3,0;MQSB=0.991023;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,110:3:0 0,39,255:13:0 +X 424 . A <*> 0 . DP=32;I16=19,13,0,0,1147,41685,0,0,1827,106923,0,0,539,11867,0,0;QS=3,0;MQSB=0.991023;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,106:3:0 0,39,255:13:0 +X 425 . A <*> 0 . DP=29;I16=16,13,0,0,1070,40616,0,0,1647,96123,0,0,542,11900,0,0;QS=3,0;MQSB=0.976248;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,111:3:0 0,33,249:11:0 +X 426 . T <*> 0 . DP=29;I16=16,12,0,0,997,36561,0,0,1587,92523,0,0,519,11287,0,0;QS=3,0;MQSB=0.982906;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,105:3:0 0,30,225:10:0 +X 427 . A <*> 0 . DP=29;I16=16,13,0,0,1024,37266,0,0,1647,96123,0,0,546,11952,0,0;QS=3,0;MQSB=0.976248;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,111:3:0 0,33,242:11:0 +X 428 . C <*> 0 . DP=29;I16=16,13,0,0,1064,39706,0,0,1647,96123,0,0,548,12020,0,0;QS=3,0;MQSB=0.976248;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,111:3:0 0,33,254:11:0 +X 429 . T <*> 0 . DP=30;I16=16,14,0,0,1150,44918,0,0,1707,99723,0,0,549,12067,0,0;QS=3,0;MQSB=0.969373;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,115:3:0 0,33,255:11:0 +X 430 . G <*> 0 . DP=30;I16=16,14,0,0,1113,42443,0,0,1707,99723,0,0,551,12145,0,0;QS=3,0;MQSB=0.969373;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,112:3:0 0,33,246:11:0 +X 431 . G <*> 0 . DP=30;I16=14,14,0,0,1003,36953,0,0,1587,92523,0,0,553,12255,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,101:3:0 0,30,225:10:0 +X 432 . T <*> 0 . DP=28;I16=14,14,0,0,1049,39621,0,0,1587,92523,0,0,556,12346,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,114:3:0 0,30,255:10:0 +X 433 . T <*> 0 . DP=28;I16=14,12,0,0,949,35443,0,0,1467,85323,0,0,509,11217,0,0;QS=3,0;MQSB=0.967472;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,112:3:0 0,27,227:9:0 +X 434 . T <*> 0 . DP=29;I16=15,14,0,0,1036,37654,0,0,1647,96123,0,0,561,12567,0,0;QS=3,0;MQSB=0.960561;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,98:3:0 0,30,243:10:0 +X 435 . A <*> 0 . DP=29;I16=15,13,0,0,1024,37970,0,0,1587,92523,0,0,556,12560,0,0;QS=3,0;MQSB=0.968414;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,103:3:0 0,30,237:10:0 +X 436 . T <*> 0 . DP=28;I16=14,14,0,0,998,36220,0,0,1587,92523,0,0,564,12654,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,110:3:0 0,27,223:9:0 +X 437 . T <*> 0 . DP=28;I16=13,14,0,0,990,36832,0,0,1558,91682,0,0,549,12435,0,0;QS=3,0;MQSB=0.999706;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,109:3:0 0,24,207:8:0 +X 438 . A <*> 0 . DP=28;I16=14,13,0,0,972,35640,0,0,1527,88923,0,0,540,12082,0,0;QS=3,0;MQSB=0.9585;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,107:3:0 0,24,216:8:0 +X 439 . C <*> 0 . DP=28;I16=14,14,0,0,1055,40273,0,0,1587,92523,0,0,563,12649,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,107:3:0 0,27,224:9:0 +X 440 . A <*> 0 . DP=28;I16=14,14,0,0,1095,43251,0,0,1587,92523,0,0,561,12615,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,115:3:0 0,27,247:9:0 +X 441 . G <*> 0 . DP=29;I16=15,14,0,0,1068,40344,0,0,1647,96123,0,0,559,12605,0,0;QS=3,0;MQSB=0.960561;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,104:3:0 0,27,198:9:0 +X 442 . A <*> 0 . DP=29;I16=15,14,0,0,1091,41507,0,0,1647,96123,0,0,558,12620,0,0;QS=3,0;MQSB=0.960561;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,112:3:0 0,27,233:9:0 +X 443 . A <*> 0 . DP=30;I16=15,14,0,0,1173,49439,0,0,1647,96123,0,0,557,12661,0,0;QS=3,0;MQSB=0.960561;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,129:3:0 0,27,246:9:0 +X 444 . G <*> 0 . DP=29;I16=15,13,0,0,1095,44661,0,0,1587,92523,0,0,557,12727,0,0;QS=3,0;MQSB=0.968414;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,91:2:0 0,27,227:9:0 +X 445 . C <*> 0 . DP=30;I16=16,13,0,0,1100,43706,0,0,1647,96123,0,0,557,12817,0,0;QS=3,0;MQSB=0.976248;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,111:3:0 0,27,219:9:0 +X 446 . A <*> 0 . DP=30;I16=16,13,0,0,1107,44265,0,0,1647,96123,0,0,557,12881,0,0;QS=3,0;MQSB=0.976248;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,115:3:0 0,27,232:9:0 +X 447 . C <*> 0 . DP=29;I16=16,12,0,0,1108,45364,0,0,1618,95282,0,0,555,12817,0,0;QS=3,0;MQSB=0.856268;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,114:3:0 0,27,235:9:0 +X 448 . T <*> 0 . DP=29;I16=16,12,0,0,1125,47237,0,0,1618,95282,0,0,553,12773,0,0;QS=3,0;MQSB=0.856268;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,118:3:0 0,27,240:9:0 +X 449 . A <*> 0 . DP=28;I16=15,12,0,0,1091,45981,0,0,1558,91682,0,0,552,12748,0,0;QS=3,0;MQSB=0.84246;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,90:2:0 0,27,245:9:0 +X 450 . G <*> 0 . DP=28;I16=15,12,0,0,1069,44603,0,0,1558,91682,0,0,551,12741,0,0;QS=3,0;MQSB=0.84246;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,91:2:0 0,27,233:9:0 +X 451 . A <*> 0 . DP=28;I16=15,12,0,0,1021,41371,0,0,1558,91682,0,0,550,12752,0,0;QS=3,0;MQSB=0.84246;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,93:2:0 0,27,244:9:0 +X 452 . A <*> 0 . DP=31;I16=18,11,0,0,1079,43353,0,0,1678,98882,0,0,530,12420,0,0;QS=3,0;MQSB=0.884952;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,110:3:0 0,24,225:8:0 +X 453 . A <*> 0 . DP=31;I16=17,11,0,0,1037,41069,0,0,1649,98041,0,0,508,11882,0,0;QS=3,0;MQSB=0.967085;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,111:3:0 0,21,221:7:0 +X 454 . A <*> 0 . DP=31;I16=18,12,0,0,1158,47028,0,0,1738,102482,0,0,554,12904,0,0;QS=3,0;MQSB=0.878946;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,113:3:0 0,30,255:10:0 +X 455 . T <*> 0 . DP=32;I16=17,13,0,0,1148,46574,0,0,1715,100251,0,0,550,12864,0,0;QS=3,0;MQSB=0.973855;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,113:3:0 0,33,255:11:0 +X 456 . G <*> 0 . DP=32;I16=17,13,0,0,1161,47287,0,0,1746,103010,0,0,534,12296,0,0;QS=3,0;MQSB=0.998031;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,116:3:0 0,30,245:10:0 +X 457 . C <*> 0 . DP=33;I16=19,13,0,0,1218,48642,0,0,1835,107451,0,0,563,12967,0,0;QS=3,0;MQSB=0.985204;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,118:3:0 0,33,255:11:0 +X 458 . A <*> 0 . DP=33;I16=19,13,0,0,1226,49034,0,0,1835,107451,0,0,568,12990,0,0;QS=3,0;MQSB=0.985204;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,111:3:0 0,33,255:11:0 +X 459 . T <*> 0 . DP=33;I16=18,13,0,0,1167,46981,0,0,1775,103851,0,0,565,12945,0,0;QS=3,0;MQSB=0.980167;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,92:2:0 0,33,255:11:0 +X 460 . G <*> 0 . DP=32;I16=19,12,0,0,1219,50105,0,0,1775,103851,0,0,575,12929,0,0;QS=3,0;MQSB=0.989977;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,116:3:0 0,30,255:10:0 +X 461 . T <*> 0 . DP=32;I16=19,12,0,0,1213,49819,0,0,1775,103851,0,0,577,12845,0,0;QS=3,0;MQSB=0.989977;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,115:3:0 0,30,255:10:0 +X 462 . G <*> 0 . DP=32;I16=19,12,0,0,1190,48962,0,0,1775,103851,0,0,580,12792,0,0;QS=3,0;MQSB=0.989977;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,119:4:0 0,30,241:10:0 +X 463 . G <*> 0 . DP=32;I16=19,12,0,0,1114,44214,0,0,1775,103851,0,0,584,12770,0,0;QS=3,0;MQSB=0.989977;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,114:4:0 0,30,221:10:0 +X 464 . A <*> 0 . DP=32;I16=18,11,0,0,1100,43908,0,0,1686,99410,0,0,556,12106,0,0;QS=3,0;MQSB=0.99095;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,133:4:0 0,24,213:8:0 +X 465 . C <*> 0 . DP=33;I16=20,11,0,0,1191,48085,0,0,1775,103851,0,0,586,12786,0,0;QS=3,0;MQSB=0.996597;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,140:5:0 0,27,231:9:0 +X 466 . A <*> 0 . DP=34;I16=21,12,0,0,1293,53311,0,0,1895,111051,0,0,597,12897,0,0;QS=3,0;MQSB=0.995633;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,154:5:0 0,30,255:10:0 +X 467 . A <*> 0 . DP=34;I16=21,11,0,0,1256,51450,0,0,1835,107451,0,0,597,12891,0,0;QS=3,0;MQSB=0.998231;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,157:5:0 0,27,248:9:0 +X 468 . A <*> 0 . DP=35;I16=22,12,0,0,1274,51268,0,0,1955,114651,0,0,604,12904,0,0;QS=3,0;MQSB=0.997406;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,154:5:0 0,30,251:10:0 +X 469 . A <*> 0 . DP=35;I16=22,12,0,0,1285,52989,0,0,1955,114651,0,0,608,12940,0,0;QS=3,0;MQSB=0.997406;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,146:5:0 0,30,255:10:0 +X 470 . G <*> 0 . DP=35;I16=22,12,0,0,1281,51055,0,0,1955,114651,0,0,612,13016,0,0;QS=3,0;MQSB=0.997406;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,148:5:0 0,30,238:10:0 +X 471 . T <*> 0 . DP=36;I16=22,11,0,0,1239,49021,0,0,1918,113282,0,0,599,12825,0,0;QS=3,0;MQSB=0.915545;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,150:5:0 0,27,232:9:0 +X 472 . T <*> 0 . DP=35;I16=21,12,0,0,1245,48915,0,0,1926,113810,0,0,595,12559,0,0;QS=3,0;MQSB=0.988858;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,153:5:0 0,27,237:9:0 +X 473 . G <*> 0 . DP=35;I16=21,12,0,0,1307,53473,0,0,1926,113810,0,0,599,12651,0,0;QS=3,0;MQSB=0.988858;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,141:5:0 0,27,249:9:0 +X 474 . G <*> 0 . DP=36;I16=22,12,0,0,1284,51708,0,0,1986,117410,0,0,602,12734,0,0;QS=3,0;MQSB=0.986937;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,131:5:0 0,30,255:10:0 +X 475 . G <*> 0 . DP=36;I16=23,12,0,0,1311,51609,0,0,2015,118251,0,0,631,13485,0,0;QS=3,0;MQSB=0.998642;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,141:5:0 0,33,252:11:0 +X 476 . A <*> 0 . DP=36;I16=23,12,0,0,1312,52078,0,0,2015,118251,0,0,634,13606,0,0;QS=3,0;MQSB=0.998642;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,157:5:0 0,33,255:11:0 +X 477 . T <*> 0 . DP=36;I16=23,12,0,0,1318,52668,0,0,2015,118251,0,0,637,13773,0,0;QS=3,0;MQSB=0.998642;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,148:5:0 0,33,255:11:0 +X 478 . T <*> 0 . DP=38;I16=25,12,0,0,1338,51774,0,0,2135,125451,0,0,637,13833,0,0;QS=3,0;MQSB=0.999868;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,18,154:6:0 0,33,255:11:0 +X 479 . A <*> 0 . DP=38;I16=25,12,0,0,1420,57788,0,0,2135,125451,0,0,639,13935,0,0;QS=3,0;MQSB=0.999868;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,18,163:6:0 0,33,255:11:0 +X 480 . G <*> 0 . DP=37;I16=25,11,0,0,1438,60172,0,0,2075,121851,0,0,641,14029,0,0;QS=3,0;MQSB=0.999853;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,165:6:0 0,33,255:11:0 +X 481 . G <*> 0 . DP=37;I16=25,11,0,0,1392,55824,0,0,2075,121851,0,0,642,14112,0,0;QS=3,0;MQSB=0.999853;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,165:6:0 0,33,255:11:0 +X 482 . A <*> 0 . DP=37;I16=24,11,0,0,1352,55134,0,0,2015,118251,0,0,618,13608,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,143:5:0 0,33,255:11:0 +X 483 . G <*> 0 . DP=37;I16=24,12,0,0,1417,57747,0,0,2075,121851,0,0,642,14240,0,0;QS=3,0;MQSB=0.999437;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,165:6:0 0,33,255:11:0 +X 484 . A <*> 0 . DP=36;I16=24,11,0,0,1340,53992,0,0,2015,118251,0,0,643,14281,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,168:6:0 0,33,255:11:0 +X 485 . G <*> 0 . DP=35;I16=23,12,0,0,1329,51411,0,0,2015,118251,0,0,669,14931,0,0;QS=3,0;MQSB=0.998642;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,160:6:0 0,33,255:11:0 +X 486 . A <*> 0 . DP=34;I16=22,12,0,0,1311,51523,0,0,1955,114651,0,0,671,14989,0,0;QS=3,0;MQSB=0.997406;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,173:6:0 0,33,255:11:0 +X 487 . G <*> 0 . DP=34;I16=22,12,0,0,1306,50760,0,0,1955,114651,0,0,672,15030,0,0;QS=3,0;MQSB=0.997406;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,169:6:0 0,33,255:11:0 +X 488 . A <*> 0 . DP=35;I16=22,12,0,0,1274,48140,0,0,1986,117410,0,0,646,14380,0,0;QS=3,0;MQSB=0.986937;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,177:6:0 0,30,255:10:0 +X 489 . A <*> 0 . DP=35;I16=23,12,0,0,1264,46916,0,0,2015,118251,0,0,671,15015,0,0;QS=3,0;MQSB=0.998642;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,175:6:0 0,33,255:11:0 +X 490 . A <*> 0 . DP=36;I16=24,12,0,0,1332,50280,0,0,2075,121851,0,0,671,15061,0,0;QS=3,0;MQSB=0.999437;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,188:7:0 0,33,255:11:0 +X 491 . T <*> 0 . DP=36;I16=24,12,0,0,1284,46802,0,0,2075,121851,0,0,671,15093,0,0;QS=3,0;MQSB=0.999437;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,178:7:0 0,33,255:11:0 +X 492 . G <*> 0 . DP=35;I16=21,12,0,0,1252,48326,0,0,1926,113810,0,0,621,13859,0,0;QS=3,0;MQSB=0.988858;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,172:6:0 0,30,251:10:0 +X 493 . A <*> 0 . DP=34;I16=22,11,0,0,1273,49481,0,0,1926,113810,0,0,650,14672,0,0;QS=3,0;MQSB=0.981935;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,186:7:0 0,24,240:8:0 +X 494 . A <*> 0 . DP=34;I16=22,12,0,0,1326,52604,0,0,1986,117410,0,0,672,15182,0,0;QS=3,0;MQSB=0.986937;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,196:7:0 0,27,255:9:0 +X 495 . G <*> 0 . DP=34;I16=21,12,0,0,1255,48577,0,0,1926,113810,0,0,647,14611,0,0;QS=3,0;MQSB=0.988858;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,168:6:0 0,27,244:9:0 +X 496 . A <*> 0 . DP=34;I16=22,12,0,0,1250,46926,0,0,1986,117410,0,0,670,15220,0,0;QS=3,0;MQSB=0.986937;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,186:7:0 0,27,249:9:0 +X 497 . C <*> 0 . DP=34;I16=22,12,0,0,1250,47006,0,0,1986,117410,0,0,665,15087,0,0;QS=3,0;MQSB=0.986937;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,164:7:0 0,27,239:9:0 +X 498 . A <*> 0 . DP=34;I16=22,12,0,0,1286,49158,0,0,1986,117410,0,0,661,14987,0,0;QS=3,0;MQSB=0.986937;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,185:7:0 0,27,252:9:0 +X 499 . T <*> 0 . DP=34;I16=23,11,0,0,1224,45284,0,0,1986,117410,0,0,659,14919,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,183:7:0 0,30,255:10:0 +X 500 . A <*> 0 . DP=34;I16=23,11,0,0,1230,45152,0,0,1986,117410,0,0,657,14833,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,179:7:0 0,30,255:10:0 +X 501 . T <*> 0 . DP=33;I16=23,10,0,0,1241,47167,0,0,1926,113810,0,0,656,14778,0,0;QS=3,0;MQSB=0.972757;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,186:7:0 0,27,241:9:0 +X 502 . G <*> 0 . DP=33;I16=23,10,0,0,1215,45829,0,0,1926,113810,0,0,655,14753,0,0;QS=3,0;MQSB=0.972757;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,183:7:0 0,27,235:9:0 +X 503 . T <*> 0 . DP=34;I16=23,11,0,0,1194,43366,0,0,1986,117410,0,0,654,14758,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,177:7:0 0,27,234:9:0 +X 504 . C <*> 0 . DP=34;I16=23,11,0,0,1218,45552,0,0,1986,117410,0,0,651,14643,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,183:7:0 0,27,219:9:0 +X 505 . C <*> 0 . DP=35;I16=23,11,0,0,1207,44321,0,0,1986,117410,0,0,641,14509,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,189:7:0 0,27,221:9:0 +X 506 . A <*> 0 . DP=35;I16=24,11,0,0,1266,46776,0,0,2046,121010,0,0,646,14504,0,0;QS=3,0;MQSB=0.977529;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,188:7:0 0,27,231:9:0 +X 507 . C <*> 0 . DP=35;I16=23,11,0,0,1220,45016,0,0,1986,117410,0,0,635,14401,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,183:7:0 0,27,226:9:0 +X 508 . A <*> 0 . DP=34;I16=24,10,0,0,1204,44542,0,0,1986,117410,0,0,643,14491,0,0;QS=3,0;MQSB=0.970272;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,189:7:0 0,27,220:9:0 +X 509 . C <*> 0 . DP=34;I16=24,10,0,0,1272,48272,0,0,1986,117410,0,0,640,14430,0,0;QS=3,0;MQSB=0.970272;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,186:7:0 0,27,241:9:0 +X 510 . A <*> 0 . DP=34;I16=22,11,0,0,1194,44196,0,0,1926,113810,0,0,613,13773,0,0;QS=3,0;MQSB=0.981935;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,187:7:0 0,24,221:8:0 +X 511 . A <*> 0 . DP=34;I16=23,11,0,0,1222,45562,0,0,1986,117410,0,0,637,14395,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,195:7:0 0,24,233:8:0 +X 512 . A C,<*> 0 . DP=33;I16=22,10,0,1,1121,40793,13,169,1866,110210,60,3600,628,14340,9,81;QS=2.97719,0.022807,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.981935;BQB=1;MQ0F=0 PL:DP:DV 0,39,255,51,255,255:18:1 0,21,183,21,183,183:7:0 0,24,231,24,231,231:8:0 +X 513 . A <*> 0 . DP=32;I16=20,10,0,0,1115,42183,0,0,1746,103010,0,0,598,13624,0,0;QS=3,0;MQSB=0.980594;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,175:6:0 0,24,233:8:0 +X 514 . A T,<*> 0 . DP=32;I16=20,9,0,1,1066,40004,16,256,1686,99410,60,3600,586,13500,11,121;QS=2.97075,0.0292505,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.980594;BQB=1;MQ0F=0 PL:DP:DV 0,31,255,45,255,255:16:1 0,18,171,18,171,171:6:0 0,24,235,24,235,235:8:0 +X 515 . C <*> 0 . DP=32;I16=18,10,0,0,1010,37294,0,0,1626,95810,0,0,561,12915,0,0;QS=3,0;MQSB=0.986018;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,167:6:0 0,24,211:8:0 +X 516 . C <*> 0 . DP=32;I16=21,10,0,0,1100,40570,0,0,1806,106610,0,0,612,13954,0,0;QS=3,0;MQSB=0.977926;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,187:7:0 0,24,215:8:0 +X 517 . T <*> 0 . DP=33;I16=23,10,0,0,1269,49995,0,0,1926,113810,0,0,636,14626,0,0;QS=3,0;MQSB=0.972757;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,201:7:0 0,24,242:8:0 +X 518 . G <*> 0 . DP=34;I16=24,10,0,0,1247,46839,0,0,1986,117410,0,0,636,14696,0,0;QS=3,0;MQSB=0.970272;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,182:7:0 0,24,220:8:0 +X 519 . T <*> 0 . DP=36;I16=25,11,0,0,1283,46693,0,0,2106,124610,0,0,636,14742,0,0;QS=3,0;MQSB=0.975394;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,21,177:7:0 0,24,224:8:0 +X 520 . T <*> 0 . DP=36;I16=24,11,0,0,1238,44894,0,0,2046,121010,0,0,613,14193,0,0;QS=3,0;MQSB=0.977529;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,180:7:0 0,24,223:8:0 +X 521 . C <*> 0 . DP=34;I16=25,9,0,0,1280,49454,0,0,1986,117410,0,0,641,14875,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,191:7:0 0,21,204:7:0 +X 522 . A <*> 0 . DP=32;I16=24,8,0,0,1158,43228,0,0,1897,112969,0,0,646,14960,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,185:7:0 0,15,170:5:0 +X 523 . T G,<*> 0 . DP=32;I16=23,8,1,0,1184,45708,15,225,1837,109369,60,3600,626,14446,25,625;QS=2.9794,0.0206044,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.872525;BQB=1;MQ0F=0 PL:DP:DV 0,44,255,57,255,255:20:1 0,21,191,21,191,191:7:0 0,15,166,15,166,166:5:0 +X 524 . T <*> 0 . DP=32;I16=24,7,0,0,1084,39474,0,0,1837,109369,0,0,629,14483,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,194:7:0 0,12,140:4:0 +X 525 . G <*> 0 . DP=32;I16=24,7,0,0,1181,45669,0,0,1837,109369,0,0,631,14495,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,188:7:0 0,12,129:4:0 +X 526 . C <*> 0 . DP=32;I16=24,7,0,0,1146,43950,0,0,1860,111600,0,0,633,14531,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,185:7:0 0,12,131:4:0 +X 527 . A <*> 0 . DP=33;I16=24,8,0,0,1209,46265,0,0,1897,112969,0,0,636,14634,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,194:7:0 0,18,181:6:0 +X 528 . G <*> 0 . DP=33;I16=24,8,0,0,1256,49824,0,0,1897,112969,0,0,634,14484,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,18,169:6:0 0,18,193:6:0 +X 529 . C <*> 0 . DP=32;I16=24,7,0,0,1148,44362,0,0,1837,109369,0,0,633,14357,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,187:7:0 0,18,184:6:0 +X 530 . T <*> 0 . DP=32;I16=25,7,0,0,1244,49168,0,0,1897,112969,0,0,657,14883,0,0;QS=3,0;MQSB=0.850154;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,196:7:0 0,18,202:6:0 +X 531 . T <*> 0 . DP=32;I16=25,7,0,0,1177,44171,0,0,1897,112969,0,0,654,14714,0,0;QS=3,0;MQSB=0.850154;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,181:7:0 0,18,193:6:0 +X 532 . T <*> 0 . DP=32;I16=24,7,0,0,1153,43543,0,0,1837,109369,0,0,630,14116,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,181:7:0 0,18,192:6:0 +X 533 . C <*> 0 . DP=32;I16=24,7,0,0,1142,43940,0,0,1837,109369,0,0,619,13649,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,178:7:0 0,18,180:6:0 +X 534 . T <*> 0 . DP=31;I16=24,6,0,0,1212,49426,0,0,1777,105769,0,0,615,13479,0,0;QS=3,0;MQSB=0.82403;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,205:7:0 0,18,205:6:0 +X 535 . A <*> 0 . DP=31;I16=24,6,0,0,1080,39870,0,0,1777,105769,0,0,611,13341,0,0;QS=3,0;MQSB=0.82403;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,194:7:0 0,18,189:6:0 +X 536 . C <*> 0 . DP=31;I16=24,7,0,0,1097,40707,0,0,1837,109369,0,0,631,13809,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,184:7:0 0,18,157:6:0 +X 537 . C <*> 0 . DP=31;I16=22,7,0,0,1034,38564,0,0,1717,102169,0,0,587,12861,0,0;QS=3,0;MQSB=0.854582;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,172:7:0 0,18,183:6:0 +X 538 . A <*> 0 . DP=31;I16=24,7,0,0,1138,42478,0,0,1837,109369,0,0,620,13536,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,189:7:0 0,18,181:6:0 +X 539 . T <*> 0 . DP=31;I16=24,7,0,0,1134,42070,0,0,1837,109369,0,0,614,13422,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,178:7:0 0,18,181:6:0 +X 540 . C <*> 0 . DP=31;I16=24,7,0,0,1148,43768,0,0,1837,109369,0,0,608,13340,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,177:7:0 0,18,178:6:0 +X 541 . A <*> 0 . DP=32;I16=24,6,0,0,1083,40483,0,0,1777,105769,0,0,551,11991,0,0;QS=3,0;MQSB=0.82403;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,180:8:0 0,15,150:5:0 +X 542 . C <*> 0 . DP=33;I16=25,6,0,0,1123,41759,0,0,1837,109369,0,0,570,12552,0,0;QS=3,0;MQSB=0.822578;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,172:8:0 0,18,174:6:0 +X 543 . C <*> 0 . DP=34;I16=25,9,0,0,1219,45959,0,0,1986,117410,0,0,601,13245,0,0;QS=3,0;MQSB=0.621145;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,27,194:9:0 0,18,188:6:0 +X 544 . A <*> 0 . DP=33;I16=24,8,0,0,1170,43898,0,0,1866,110210,0,0,570,12506,0,0;QS=3,0;MQSB=0.579578;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,192:8:0 0,18,180:6:0 +X 545 . A <*> 0 . DP=33;I16=25,8,0,0,1174,43602,0,0,1926,113810,0,0,587,12951,0,0;QS=3,0;MQSB=0.576102;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,190:8:0 0,18,184:6:0 +X 546 . A <*> 0 . DP=32;I16=24,8,0,0,1126,41444,0,0,1866,110210,0,0,580,12802,0,0;QS=3,0;MQSB=0.579578;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,166:7:0 0,18,193:6:0 +X 547 . A <*> 0 . DP=32;I16=24,7,0,0,1129,42381,0,0,1806,106610,0,0,547,12009,0,0;QS=3,0;MQSB=0.525788;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,180:7:0 0,18,195:6:0 +X 548 . A <*> 0 . DP=33;I16=23,9,0,0,1153,42673,0,0,1866,110210,0,0,561,12489,0,0;QS=3,0;MQSB=0.628357;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,181:7:0 0,21,211:7:0 +X 549 . T G,<*> 0 . DP=32;I16=22,8,0,1,1101,40987,20,400,1746,103010,60,3600,530,11716,25,625;QS=2.96748,0.0325203,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.632337;BQB=1;MQ0F=0 PL:DP:DV 0,31,255,48,255,255:17:1 0,21,168,21,168,168:7:0 0,21,208,21,208,208:7:0 +X 550 . T <*> 0 . DP=32;I16=22,9,0,0,1052,37298,0,0,1806,106610,0,0,548,12176,0,0;QS=3,0;MQSB=0.632337;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,150:7:0 0,21,220:7:0 +X 551 . G <*> 0 . DP=31;I16=22,9,0,0,1121,41639,0,0,1806,106610,0,0,541,12045,0,0;QS=3,0;MQSB=0.632337;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,172:7:0 0,21,208:7:0 +X 552 . C <*> 0 . DP=30;I16=21,9,0,0,1093,41365,0,0,1746,103010,0,0,535,11947,0,0;QS=3,0;MQSB=0.636601;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,167:7:0 0,21,208:7:0 +X 553 . A <*> 0 . DP=30;I16=20,8,0,0,981,35387,0,0,1626,95810,0,0,485,10831,0,0;QS=3,0;MQSB=0.596163;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,150:6:0 0,21,194:7:0 +X 554 . A <*> 0 . DP=30;I16=19,9,0,0,975,35601,0,0,1626,95810,0,0,488,10906,0,0;QS=3,0;MQSB=0.646113;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,139:5:0 0,24,211:8:0 +X 555 . A <*> 0 . DP=30;I16=20,10,0,0,1024,36526,0,0,1746,103010,0,0,514,11392,0,0;QS=3,0;MQSB=0.679025;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,150:6:0 0,21,211:7:0 +X 556 . C <*> 0 . DP=29;I16=20,9,0,0,1055,39195,0,0,1709,101641,0,0,509,11219,0,0;QS=3,0;MQSB=0.894839;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,158:6:0 0,18,186:6:0 +X 557 . A <*> 0 . DP=27;I16=18,9,0,0,987,36749,0,0,1589,94441,0,0,506,11074,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,157:6:0 0,18,186:6:0 +X 558 . A <*> 0 . DP=27;I16=18,8,0,0,948,35808,0,0,1560,93600,0,0,477,10281,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,143:5:0 0,18,177:6:0 +X 559 . C A,<*> 0 . DP=27;I16=17,8,0,1,908,33726,14,196,1500,90000,29,841,448,9516,25,625;QS=2.92708,0.0729167,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.90038;BQB=1;MQ0F=0 PL:DP:DV 0,42,255,42,255,255:14:0 0,4,116,15,119,123:6:1 0,18,169,18,169,169:6:0 +X 560 . C <*> 0 . DP=28;I16=19,9,0,0,992,36552,0,0,1649,98041,0,0,494,10654,0,0;QS=3,0;MQSB=0.896555;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,160:6:0 0,21,181:7:0 +X 561 . A <*> 0 . DP=28;I16=18,9,0,0,963,35455,0,0,1589,94441,0,0,466,9946,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,158:6:0 0,21,194:7:0 +X 562 . C <*> 0 . DP=28;I16=18,9,0,0,1006,38392,0,0,1589,94441,0,0,463,9893,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,153:6:0 0,21,187:7:0 +X 563 . A <*> 0 . DP=27;I16=17,9,0,0,893,32413,0,0,1529,90841,0,0,460,9820,0,0;QS=3,0;MQSB=0.90038;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,149:5:0 0,21,179:7:0 +X 564 . C <*> 0 . DP=27;I16=18,9,0,0,859,28747,0,0,1589,94441,0,0,482,10402,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,121:5:0 0,21,182:7:0 +X 565 . G <*> 0 . DP=30;I16=17,9,0,0,818,26928,0,0,1560,93600,0,0,454,9764,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,96:4:0 0,21,154:7:0 +X 566 . C <*> 0 . DP=29;I16=15,11,0,0,903,33405,0,0,1529,90841,0,0,424,9084,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,155:5:0 0,18,167:6:0 +X 567 . C <*> 0 . DP=30;I16=15,12,0,0,932,33774,0,0,1589,94441,0,0,462,10178,0,0;QS=3,0;MQSB=0.935229;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,155:5:0 0,21,196:7:0 +X 568 . C <*> 0 . DP=29;I16=15,13,0,0,1057,40817,0,0,1649,98041,0,0,482,10438,0,0;QS=3,0;MQSB=0.942064;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,183:6:0 0,18,189:6:0 +X 569 . T <*> 0 . DP=30;I16=16,12,0,0,1056,41296,0,0,1649,98041,0,0,493,10655,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,190:6:0 0,21,213:7:0 +X 570 . T <*> 0 . DP=30;I16=16,12,0,0,954,34972,0,0,1680,100800,0,0,472,10086,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,157:5:0 0,21,195:7:0 +X 571 . C <*> 0 . DP=31;I16=17,12,0,0,1061,40675,0,0,1740,104400,0,0,472,10158,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,155:5:0 0,21,193:7:0 +X 572 . A <*> 0 . DP=31;I16=18,12,0,0,1102,42642,0,0,1769,105241,0,0,499,10887,0,0;QS=3,0;MQSB=0.929991;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,203:7:0 0,18,175:6:0 +X 573 . A <*> 0 . DP=31;I16=18,12,0,0,1057,38473,0,0,1769,105241,0,0,501,10975,0,0;QS=3,0;MQSB=0.929991;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,199:7:0 0,18,178:6:0 +X 574 . C A,<*> 0 . DP=31;I16=18,11,0,1,1088,41328,15,225,1740,104400,29,841,478,10422,25,625;QS=2.94071,0.0592885,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.929991;BQB=1;MQ0F=0 PL:DP:DV 0,48,255,48,255,255:16:0 0,9,170,21,173,177:8:1 0,18,173,18,173,173:6:0 +X 575 . T <*> 0 . DP=30;I16=16,10,0,0,1024,41260,0,0,1560,93600,0,0,448,9842,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,209:7:0 0,15,163:5:0 +X 576 . G <*> 0 . DP=30;I16=17,12,0,0,1047,40077,0,0,1709,101641,0,0,507,11087,0,0;QS=3,0;MQSB=0.931617;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,208:8:0 0,15,151:5:0 +X 577 . G <*> 0 . DP=30;I16=16,12,0,0,999,37747,0,0,1649,98041,0,0,489,10755,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,204:8:0 0,15,146:5:0 +X 578 . G <*> 0 . DP=29;I16=16,13,0,0,975,34803,0,0,1709,101641,0,0,520,11286,0,0;QS=3,0;MQSB=0.940317;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,198:8:0 0,15,151:5:0 +X 579 . G <*> 0 . DP=30;I16=15,13,0,0,1028,38752,0,0,1649,98041,0,0,484,10514,0,0;QS=3,0;MQSB=0.942064;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,224:8:0 0,12,145:4:0 +X 580 . A C,<*> 0 . DP=30;I16=15,14,1,0,1060,39178,16,256,1709,101641,60,3600,510,11078,17,289;QS=2.97338,0.0266223,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.946202;BQB=1;MQ0F=0 PL:DP:DV 0,34,255,48,255,255:17:1 0,24,221,24,221,221:8:0 0,15,155,15,155,155:5:0 +X 581 . A <*> 0 . DP=31;I16=16,15,0,0,1083,39215,0,0,1829,108841,0,0,530,11384,0,0;QS=3,0;MQSB=0.951229;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,223:8:0 0,15,153:5:0 +X 582 . C <*> 0 . DP=31;I16=15,15,0,0,1080,39870,0,0,1769,105241,0,0,519,11211,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,207:8:0 0,15,151:5:0 +X 583 . T <*> 0 . DP=30;I16=16,14,0,0,1136,43996,0,0,1769,105241,0,0,539,11523,0,0;QS=3,0;MQSB=0.946202;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,238:8:0 0,15,163:5:0 +X 584 . C <*> 0 . DP=31;I16=16,13,0,0,1051,39351,0,0,1709,101641,0,0,499,10619,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,207:7:0 0,15,157:5:0 +X 585 . A <*> 0 . DP=31;I16=17,14,0,0,1096,39866,0,0,1798,106082,0,0,549,11751,0,0;QS=3,0;MQSB=0.998229;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,211:8:0 0,15,157:5:0 +X 586 . T <*> 0 . DP=31;I16=16,14,0,0,1081,39839,0,0,1738,102482,0,0,546,11796,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,212:8:0 0,15,156:5:0 +X 587 . C <*> 0 . DP=31;I16=17,13,0,0,1070,39402,0,0,1769,105241,0,0,532,11350,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,201:7:0 0,15,155:5:0 +X 588 . A <*> 0 . DP=31;I16=17,14,0,0,1126,41642,0,0,1798,106082,0,0,562,12140,0,0;QS=3,0;MQSB=0.998229;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,222:8:0 0,15,164:5:0 +X 589 . A <*> 0 . DP=31;I16=17,14,0,0,1157,43973,0,0,1798,106082,0,0,568,12340,0,0;QS=3,0;MQSB=0.998229;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,236:8:0 0,15,165:5:0 +X 590 . C <*> 0 . DP=32;I16=16,14,0,0,1094,41302,0,0,1769,105241,0,0,549,11951,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,192:6:0 0,18,175:6:0 +X 591 . A <*> 0 . DP=31;I16=16,15,0,0,1165,44163,0,0,1798,106082,0,0,579,12695,0,0;QS=3,0;MQSB=0.999805;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,209:7:0 0,18,188:6:0 +X 592 . A <*> 0 . DP=31;I16=15,15,0,0,1114,42144,0,0,1738,102482,0,0,571,12651,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,215:7:0 0,18,182:6:0 +X 593 . C <*> 0 . DP=31;I16=15,14,0,0,1065,39889,0,0,1709,101641,0,0,550,12132,0,0;QS=3,0;MQSB=0.954405;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,191:6:0 0,18,174:6:0 +X 594 . A <*> 0 . DP=33;I16=16,16,0,0,1163,42917,0,0,1858,109682,0,0,572,12672,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,205:7:0 0,24,212:8:0 +X 595 . A <*> 0 . DP=33;I16=17,16,0,0,1130,39996,0,0,1918,113282,0,0,589,12905,0,0;QS=3,0;MQSB=0.999838;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,198:7:0 0,24,213:8:0 +X 596 . A <*> 0 . DP=33;I16=16,16,0,0,1059,37039,0,0,1858,109682,0,0,590,12952,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,169:7:0 0,24,230:8:0 +X 597 . C <*> 0 . DP=33;I16=17,16,0,0,1196,44890,0,0,1918,113282,0,0,592,12990,0,0;QS=3,0;MQSB=0.999838;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,204:7:0 0,24,220:8:0 +X 598 . T <*> 0 . DP=33;I16=16,16,0,0,1214,47104,0,0,1858,109682,0,0,593,13013,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,217:7:0 0,24,239:8:0 +X 599 . T <*> 0 . DP=33;I16=16,17,0,0,1183,43669,0,0,1918,113282,0,0,599,13095,0,0;QS=3,0;MQSB=0.999838;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,197:7:0 0,27,247:9:0 +X 600 . G <*> 0 . DP=32;I16=15,17,0,0,1174,44066,0,0,1858,109682,0,0,601,13145,0,0;QS=3,0;MQSB=0.999287;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,194:7:0 0,24,232:8:0 +X 601 . T <*> 0 . DP=32;I16=15,17,0,0,1114,39954,0,0,1858,109682,0,0,603,13227,0,0;QS=3,0;MQSB=0.999287;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,188:7:0 0,24,235:8:0 +X 602 . G <*> 0 . DP=32;I16=15,15,0,0,1090,40326,0,0,1769,105241,0,0,555,12091,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,185:6:0 0,24,229:8:0 +X 603 . G <*> 0 . DP=31;I16=15,16,0,0,1052,37460,0,0,1798,106082,0,0,607,13437,0,0;QS=3,0;MQSB=0.999805;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,186:7:0 0,24,219:8:0 +X 604 . T <*> 0 . DP=31;I16=14,16,0,0,1009,35893,0,0,1769,105241,0,0,564,12540,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,195:8:0 0,21,212:7:0 +X 605 . T <*> 0 . DP=31;I16=12,15,0,0,1001,37741,0,0,1589,94441,0,0,514,11258,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,200:7:0 0,21,214:7:0 +X 606 . T <*> 0 . DP=31;I16=13,16,0,0,992,35202,0,0,1709,101641,0,0,587,13125,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,189:7:0 0,24,217:8:0 +X 607 . A <*> 0 . DP=31;I16=14,16,0,0,1027,36129,0,0,1738,102482,0,0,607,13577,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,176:7:0 0,24,222:8:0 +X 608 . C <*> 0 . DP=32;I16=15,15,0,0,983,33775,0,0,1769,105241,0,0,564,12564,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,178:7:0 0,27,214:9:0 +X 609 . C <*> 0 . DP=32;I16=14,17,0,0,1074,38220,0,0,1798,106082,0,0,606,13678,0,0;QS=3,0;MQSB=0.998229;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,190:7:0 0,27,238:9:0 +X 610 . C <*> 0 . DP=32;I16=15,16,0,0,1158,44218,0,0,1829,108841,0,0,594,13444,0,0;QS=3,0;MQSB=0.951229;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,211:8:0 0,27,246:9:0 +X 611 . A <*> 0 . DP=32;I16=15,16,0,0,1080,39204,0,0,1798,106082,0,0,590,13260,0,0;QS=3,0;MQSB=0.999805;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,220:9:0 0,27,246:9:0 +X 612 . C <*> 0 . DP=33;I16=16,17,0,0,1175,43305,0,0,1918,113282,0,0,617,13993,0,0;QS=3,0;MQSB=0.999838;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,214:9:0 0,27,250:9:0 +X 613 . A <*> 0 . DP=34;I16=16,17,0,0,1131,40011,0,0,1949,116041,0,0,604,13874,0,0;QS=3,0;MQSB=0.954207;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,223:9:0 0,27,239:9:0 +X 614 . C <*> 0 . DP=34;I16=16,17,0,0,1183,43743,0,0,1949,116041,0,0,608,14022,0,0;QS=3,0;MQSB=0.954207;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,223:9:0 0,27,245:9:0 +X 615 . A <*> 0 . DP=34;I16=16,18,0,0,1199,43809,0,0,1978,116882,0,0,626,14394,0,0;QS=3,0;MQSB=0.999405;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,30,240:10:0 0,27,254:9:0 +X 616 . A <*> 0 . DP=34;I16=16,17,0,0,1190,44024,0,0,1949,116041,0,0,615,14351,0,0;QS=3,0;MQSB=0.954207;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,247:9:0 0,27,255:9:0 +X 617 . T <*> 0 . DP=33;I16=15,18,0,0,1170,43066,0,0,1918,113282,0,0,630,14624,0,0;QS=3,0;MQSB=0.998531;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,30,241:10:0 0,27,255:9:0 +X 618 . G <*> 0 . DP=34;I16=15,19,0,0,1166,41452,0,0,1978,116882,0,0,632,14706,0,0;QS=3,0;MQSB=0.997597;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,30,248:10:0 0,27,240:9:0 +X 619 . G <*> 0 . DP=32;I16=14,18,0,0,1153,42591,0,0,1858,109682,0,0,638,14816,0,0;QS=3,0;MQSB=0.997118;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,30,254:10:0 0,27,247:9:0 +X 620 . A <*> 0 . DP=32;I16=14,17,0,0,1083,39757,0,0,1798,106082,0,0,616,14176,0,0;QS=3,0;MQSB=0.998229;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,30,248:10:0 0,27,255:9:0 +X 621 . A <*> 0 . DP=32;I16=13,18,0,0,1170,45248,0,0,1798,106082,0,0,627,14519,0,0;QS=3,0;MQSB=0.995005;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,255:9:0 0,27,255:9:0 +X 622 . G <*> 0 . DP=32;I16=12,18,0,0,1060,39160,0,0,1769,105241,0,0,604,13888,0,0;QS=3,0;MQSB=0.968257;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,236:9:0 0,27,249:9:0 +X 623 . A T,<*> 0 . DP=32;I16=10,18,1,0,1010,37414,15,225,1649,98041,60,3600,563,12953,25,625;QS=2.96144,0.0385604,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.969907;BQB=1;MQ0F=0 PL:DP:DV 0,20,241,33,244,246:12:1 0,24,213,24,213,213:8:0 0,27,255,27,255,255:9:0 +X 624 . C <*> 0 . DP=32;I16=13,17,0,0,1034,37292,0,0,1738,102482,0,0,607,13887,0,0;QS=3,0;MQSB=0.996503;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,220:9:0 0,27,242:9:0 +X 625 . C <*> 0 . DP=32;I16=13,18,0,0,1108,41138,0,0,1798,106082,0,0,632,14470,0,0;QS=3,0;MQSB=0.995005;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,234:9:0 0,27,249:9:0 +X 626 . A <*> 0 . DP=32;I16=13,17,0,0,1090,40718,0,0,1738,102482,0,0,607,13827,0,0;QS=3,0;MQSB=0.996503;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,237:9:0 0,27,247:9:0 +X 627 . C <*> 0 . DP=32;I16=12,18,0,0,1146,44452,0,0,1769,105241,0,0,607,13833,0,0;QS=3,0;MQSB=0.968257;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,244:9:0 0,27,255:9:0 +X 628 . T <*> 0 . DP=32;I16=11,19,0,0,1124,43114,0,0,1769,105241,0,0,608,13862,0,0;QS=3,0;MQSB=0.972375;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,249:9:0 0,24,249:8:0 +X 629 . T <*> 0 . DP=32;I16=12,19,0,0,1114,41138,0,0,1798,106082,0,0,634,14490,0,0;QS=3,0;MQSB=0.989977;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,247:9:0 0,24,226:8:0 +X 630 . A <*> 0 . DP=31;I16=11,18,0,0,1101,42885,0,0,1740,104400,0,0,610,13844,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,242:8:0 0,24,235:8:0 +X 631 . G <*> 0 . DP=31;I16=12,18,0,0,1083,40525,0,0,1769,105241,0,0,636,14474,0,0;QS=3,0;MQSB=0.929991;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,233:8:0 0,24,223:8:0 +X 632 . C <*> 0 . DP=31;I16=11,18,0,0,1105,42665,0,0,1740,104400,0,0,612,13880,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,233:8:0 0,24,224:8:0 +X 633 . A <*> 0 . DP=31;I16=12,18,0,0,1056,38190,0,0,1769,105241,0,0,638,14562,0,0;QS=3,0;MQSB=0.929991;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,218:8:0 0,24,214:8:0 +X 634 . A <*> 0 . DP=31;I16=12,18,0,0,1110,42208,0,0,1769,105241,0,0,638,14594,0,0;QS=3,0;MQSB=0.929991;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,238:8:0 0,24,229:8:0 +X 635 . C <*> 0 . DP=31;I16=11,18,0,0,1031,37871,0,0,1740,104400,0,0,613,14025,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,220:8:0 0,24,229:8:0 +X 636 . A <*> 0 . DP=31;I16=11,18,0,0,1115,43327,0,0,1740,104400,0,0,611,14005,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,228:8:0 0,24,243:8:0 +X 637 . A <*> 0 . DP=31;I16=12,18,0,0,1152,44602,0,0,1769,105241,0,0,634,14634,0,0;QS=3,0;MQSB=0.929991;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,238:8:0 0,24,242:8:0 +X 638 . A <*> 0 . DP=31;I16=12,18,0,0,1118,42406,0,0,1769,105241,0,0,631,14611,0,0;QS=3,0;MQSB=0.929991;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,235:8:0 0,24,238:8:0 +X 639 . A <*> 0 . DP=30;I16=11,18,0,0,1037,38233,0,0,1709,101641,0,0,602,13934,0,0;QS=3,0;MQSB=0.921439;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,230:8:0 0,24,227:8:0 +X 640 . A <*> 0 . DP=31;I16=11,19,0,0,1154,45368,0,0,1769,105241,0,0,596,13804,0,0;QS=3,0;MQSB=0.91982;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,242:8:0 0,24,240:8:0 +X 641 . G <*> 0 . DP=31;I16=11,19,0,0,1018,36496,0,0,1769,105241,0,0,590,13650,0,0;QS=3,0;MQSB=0.91982;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,214:8:0 0,24,218:8:0 +X 642 . G <*> 0 . DP=30;I16=11,19,0,0,1057,38459,0,0,1769,105241,0,0,610,14148,0,0;QS=3,0;MQSB=0.91982;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,187:7:0 0,24,221:8:0 +X 643 . A <*> 0 . DP=29;I16=11,17,0,0,969,35477,0,0,1649,98041,0,0,585,13605,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,199:7:0 0,24,237:8:0 +X 644 . C A,<*> 0 . DP=29;I16=9,18,1,0,898,30864,17,289,1620,97200,60,3600,549,12567,25,625;QS=2.95685,0.0431472,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,22,236,36,239,243:13:1 0,21,195,21,195,195:7:0 0,24,204,24,204,204:8:0 +X 645 . C <*> 0 . DP=30;I16=10,19,0,0,1067,40337,0,0,1709,101641,0,0,584,13274,0,0;QS=3,0;MQSB=0.909373;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,198:7:0 0,24,226:8:0 +X 646 . A T,<*> 0 . DP=31;I16=9,20,1,0,1044,38174,14,196,1740,104400,60,3600,553,12499,25,625;QS=2.97113,0.028866,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,27,255,39,255,255:14:1 0,21,197,21,197,197:7:0 0,27,229,27,229,229:9:0 +X 647 . A <*> 0 . DP=33;I16=10,21,0,0,1041,35883,0,0,1829,108841,0,0,573,12999,0,0;QS=3,0;MQSB=0.906252;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,189:7:0 0,30,213:10:0 +X 648 . A <*> 0 . DP=33;I16=11,22,0,0,1030,34122,0,0,1949,116041,0,0,594,13478,0,0;QS=3,0;MQSB=0.915545;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,188:7:0 0,30,194:10:0 +X 649 . C <*> 0 . DP=32;I16=10,21,0,0,1099,39879,0,0,1860,111600,0,0,566,12738,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,188:7:0 0,27,217:9:0 +X 650 . T <*> 0 . DP=31;I16=11,18,0,0,1006,37114,0,0,1709,101641,0,0,549,12407,0,0;QS=3,0;MQSB=0.921439;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,187:6:0 0,24,226:8:0 +X 651 . C <*> 0 . DP=32;I16=11,20,0,0,1117,41181,0,0,1829,108841,0,0,581,13107,0,0;QS=3,0;MQSB=0.918304;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,186:6:0 0,27,229:9:0 +X 652 . C <*> 0 . DP=32;I16=9,21,0,0,1126,43084,0,0,1769,105241,0,0,557,12423,0,0;QS=3,0;MQSB=0.893237;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,196:6:0 0,24,213:8:0 +X 653 . T <*> 0 . DP=33;I16=9,23,0,0,1141,42631,0,0,1889,112441,0,0,556,12382,0,0;QS=3,0;MQSB=0.890331;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,198:6:0 0,24,225:8:0 +X 654 . G <*> 0 . DP=33;I16=10,23,0,0,1171,43025,0,0,1949,116041,0,0,578,12798,0,0;QS=3,0;MQSB=0.903508;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,191:6:0 0,24,223:8:0 +X 655 . G <*> 0 . DP=32;I16=10,22,0,0,1118,40202,0,0,1889,112441,0,0,575,12573,0,0;QS=3,0;MQSB=0.904837;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,181:6:0 0,24,213:8:0 +X 656 . T <*> 0 . DP=32;I16=10,22,0,0,1090,38566,0,0,1889,112441,0,0,571,12333,0,0;QS=3,0;MQSB=0.904837;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,185:6:0 0,24,213:8:0 +X 657 . A <*> 0 . DP=32;I16=10,21,0,0,1100,40006,0,0,1829,108841,0,0,557,12029,0,0;QS=3,0;MQSB=0.906252;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,183:6:0 0,24,191:8:0 +X 658 . C <*> 0 . DP=32;I16=10,21,0,0,1115,41039,0,0,1829,108841,0,0,542,11520,0,0;QS=3,0;MQSB=0.906252;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,168:5:0 0,24,211:8:0 +X 659 . A <*> 0 . DP=32;I16=10,21,0,0,1141,42897,0,0,1829,108841,0,0,547,11685,0,0;QS=3,0;MQSB=0.906252;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,191:6:0 0,24,216:8:0 +X 660 . T <*> 0 . DP=33;I16=10,22,0,0,1139,41887,0,0,1889,112441,0,0,553,11659,0,0;QS=3,0;MQSB=0.904837;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,186:6:0 0,24,214:8:0 +X 661 . G <*> 0 . DP=32;I16=9,22,0,0,1107,41531,0,0,1829,108841,0,0,549,11549,0,0;QS=3,0;MQSB=0.891738;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,191:6:0 0,21,188:7:0 +X 662 . C <*> 0 . DP=32;I16=8,22,0,0,1087,40811,0,0,1800,108000,0,0,523,10991,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,192:6:0 0,21,187:7:0 +X 663 . A <*> 0 . DP=32;I16=9,22,0,0,1036,36816,0,0,1829,108841,0,0,540,11388,0,0;QS=3,0;MQSB=0.891738;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,192:6:0 0,21,186:7:0 +X 664 . A <*> 0 . DP=32;I16=9,23,0,0,1125,40759,0,0,1889,112441,0,0,552,11628,0,0;QS=3,0;MQSB=0.890331;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,188:6:0 0,21,184:7:0 +X 665 . C <*> 0 . DP=30;I16=9,21,0,0,1075,39697,0,0,1769,105241,0,0,550,11650,0,0;QS=3,0;MQSB=0.893237;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,186:6:0 0,21,184:7:0 +X 666 . T <*> 0 . DP=29;I16=9,20,0,0,1096,41946,0,0,1709,101641,0,0,547,11607,0,0;QS=3,0;MQSB=0.894839;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,171:5:0 0,21,194:7:0 +X 667 . G <*> 0 . DP=31;I16=11,19,0,0,1037,37627,0,0,1769,105241,0,0,524,11198,0,0;QS=3,0;MQSB=0.91982;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,189:6:0 0,21,188:7:0 +X 668 . A <*> 0 . DP=31;I16=11,20,0,0,1102,39980,0,0,1829,108841,0,0,543,11625,0,0;QS=3,0;MQSB=0.918304;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,190:6:0 0,21,187:7:0 +X 669 . C <*> 0 . DP=30;I16=10,19,0,0,1051,38869,0,0,1740,104400,0,0,528,11464,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,182:6:0 0,21,189:7:0 +X 670 . A <*> 0 . DP=30;I16=11,19,0,0,1121,43423,0,0,1769,105241,0,0,540,11642,0,0;QS=3,0;MQSB=0.91982;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,194:6:0 0,21,205:7:0 +X 671 . G <*> 0 . DP=30;I16=11,19,0,0,1101,41035,0,0,1769,105241,0,0,537,11637,0,0;QS=3,0;MQSB=0.91982;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,181:6:0 0,21,191:7:0 +X 672 . A <*> 0 . DP=30;I16=10,19,0,0,1031,37795,0,0,1740,104400,0,0,521,11479,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,185:6:0 0,21,185:7:0 +X 673 . T <*> 0 . DP=29;I16=8,19,0,0,954,34984,0,0,1589,94441,0,0,497,10885,0,0;QS=3,0;MQSB=0.880529;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,126:4:0 0,21,192:7:0 +X 674 . G <*> 0 . DP=29;I16=10,18,0,0,974,35736,0,0,1649,98041,0,0,497,10827,0,0;QS=3,0;MQSB=0.911099;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,146:5:0 0,21,185:7:0 +X 675 . A <*> 0 . DP=28;I16=9,19,0,0,996,36338,0,0,1649,98041,0,0,517,11389,0,0;QS=3,0;MQSB=0.896555;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,124:4:0 0,21,189:7:0 +X 676 . A <*> 0 . DP=29;I16=8,19,0,0,988,36578,0,0,1589,94441,0,0,462,10106,0,0;QS=3,0;MQSB=0.880529;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,128:4:0 0,21,186:7:0 +X 677 . T <*> 0 . DP=29;I16=9,20,0,0,1006,36126,0,0,1709,101641,0,0,507,11303,0,0;QS=3,0;MQSB=0.894839;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,120:4:0 0,21,192:7:0 +X 678 . C <*> 0 . DP=29;I16=9,20,0,0,1020,36984,0,0,1709,101641,0,0,502,11280,0,0;QS=3,0;MQSB=0.894839;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,117:4:0 0,21,191:7:0 +X 679 . T <*> 0 . DP=27;I16=6,19,0,0,902,33612,0,0,1469,87241,0,0,460,10414,0,0;QS=3,0;MQSB=0.833024;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,96:3:0 0,21,195:7:0 +X 680 . C <*> 0 . DP=26;I16=7,18,0,0,879,32295,0,0,1469,87241,0,0,468,10482,0,0;QS=3,0;MQSB=0.862128;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,98:3:0 0,21,181:7:0 +X 681 . A <*> 0 . DP=27;I16=7,17,0,0,844,30190,0,0,1409,83641,0,0,465,10425,0,0;QS=3,0;MQSB=0.864405;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,106:3:0 0,21,174:7:0 +X 682 . A <*> 0 . DP=27;I16=7,20,0,0,919,32179,0,0,1589,94441,0,0,500,11096,0,0;QS=3,0;MQSB=0.858077;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,145:5:0 0,21,176:7:0 +X 683 . A <*> 0 . DP=29;I16=8,21,0,0,949,32735,0,0,1709,101641,0,0,499,11103,0,0;QS=3,0;MQSB=0.876998;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,172:6:0 0,21,167:7:0 +X 684 . C <*> 0 . DP=29;I16=6,21,0,0,802,24468,0,0,1589,94441,0,0,473,10459,0,0;QS=3,0;MQSB=0.829029;MQ0F=0 PL:DP:DV 0,45,251:15:0 0,15,118:5:0 0,21,145:7:0 +X 685 . G <*> 0 . DP=28;I16=6,21,0,0,908,32092,0,0,1620,97200,0,0,498,11090,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,130:5:0 0,21,175:7:0 +X 686 . C <*> 0 . DP=28;I16=7,21,0,0,977,35493,0,0,1680,100800,0,0,500,11080,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,170:6:0 0,21,180:7:0 +X 687 . A <*> 0 . DP=28;I16=6,20,0,0,900,31952,0,0,1560,93600,0,0,475,10469,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,175:6:0 0,21,174:7:0 +X 688 . T <*> 0 . DP=27;I16=6,21,0,0,937,33971,0,0,1620,97200,0,0,501,11135,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,153:6:0 0,21,187:7:0 +X 689 . T A,<*> 0 . DP=27;I16=5,20,1,0,829,28967,13,169,1500,90000,60,3600,463,10359,25,625;QS=2.97105,0.0289532,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,28,231,39,234,234:14:1 0,15,116,15,116,116:5:0 0,21,185,21,185,185:7:0 +X 690 . C <*> 0 . DP=27;I16=6,20,0,0,935,34553,0,0,1560,93600,0,0,486,10974,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,146:5:0 0,21,165:7:0 +X 691 . C <*> 0 . DP=26;I16=5,18,0,0,842,31906,0,0,1380,82800,0,0,446,10166,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,129:4:0 0,18,161:6:0 +X 692 . T <*> 0 . DP=26;I16=6,19,0,0,886,32434,0,0,1500,90000,0,0,486,11082,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,146:5:0 0,18,164:6:0 +X 693 . C <*> 0 . DP=27;I16=6,20,0,0,891,31839,0,0,1560,93600,0,0,483,11007,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,141:5:0 0,21,172:7:0 +X 694 . C <*> 0 . DP=27;I16=6,21,0,0,808,25004,0,0,1620,97200,0,0,498,11248,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,242:14:0 0,18,136:6:0 0,21,146:7:0 +X 695 . G <*> 0 . DP=25;I16=4,20,0,0,807,28037,0,0,1440,86400,0,0,476,10692,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,246:13:0 0,18,145:6:0 0,15,124:5:0 +X 696 . T <*> 0 . DP=25;I16=5,20,0,0,896,32870,0,0,1500,90000,0,0,499,11129,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,150:6:0 0,15,141:5:0 +X 697 . G <*> 0 . DP=26;I16=5,19,0,0,852,30594,0,0,1409,83641,0,0,450,9858,0,0;QS=3,0;MQSB=0.796124;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,142:5:0 0,15,120:5:0 +X 698 . T <*> 0 . DP=27;I16=6,20,0,0,917,33201,0,0,1529,90841,0,0,502,11114,0,0;QS=3,0;MQSB=0.83095;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,154:6:0 0,15,131:5:0 +X 699 . G <*> 0 . DP=28;I16=5,21,0,0,923,34103,0,0,1529,90841,0,0,498,10884,0,0;QS=3,0;MQSB=0.79189;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,163:6:0 0,15,132:5:0 +X 700 . A <*> 0 . DP=28;I16=6,22,0,0,989,35833,0,0,1618,95282,0,0,530,11626,0,0;QS=3,0;MQSB=0.904554;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,169:7:0 0,18,148:6:0 +X 701 . A <*> 0 . DP=29;I16=5,23,0,0,992,35956,0,0,1618,95282,0,0,517,11459,0,0;QS=3,0;MQSB=0.864394;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,186:7:0 0,18,144:6:0 +X 702 . A <*> 0 . DP=29;I16=5,23,0,0,1103,44105,0,0,1618,95282,0,0,520,11508,0,0;QS=3,0;MQSB=0.864394;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,204:7:0 0,18,159:6:0 +X 703 . G <*> 0 . DP=29;I16=5,23,0,0,1014,37508,0,0,1618,95282,0,0,522,11534,0,0;QS=3,0;MQSB=0.864394;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,172:7:0 0,18,144:6:0 +X 704 . A T,<*> 0 . DP=29;I16=4,23,1,0,954,34200,16,256,1558,91682,60,3600,499,10963,13,169;QS=2.97064,0.0293578,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.864394;BQB=1;MQ0F=0 PL:DP:DV 0,31,255,45,255,255:16:1 0,18,154,18,154,154:6:0 0,18,139,18,139,139:6:0 +X 705 . A <*> 0 . DP=29;I16=6,22,0,0,1042,39930,0,0,1618,95282,0,0,513,11189,0,0;QS=3,0;MQSB=0.904554;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,189:7:0 0,18,157:6:0 +X 706 . G <*> 0 . DP=30;I16=6,23,0,0,1029,37763,0,0,1678,98882,0,0,513,11225,0,0;QS=3,0;MQSB=0.900586;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,170:7:0 0,18,131:6:0 +X 707 . C <*> 0 . DP=30;I16=5,22,0,0,944,34494,0,0,1558,91682,0,0,464,10040,0,0;QS=3,0;MQSB=0.868709;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,131:5:0 0,18,134:6:0 +X 708 . C <*> 0 . DP=30;I16=6,24,0,0,898,27574,0,0,1738,102482,0,0,540,12010,0,0;QS=3,0;MQSB=0.896846;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,153:8:0 0,18,110:6:0 +X 709 . G <*> 0 . DP=29;I16=5,22,0,0,968,36130,0,0,1558,91682,0,0,507,11343,0,0;QS=3,0;MQSB=0.868709;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,178:8:0 0,15,132:5:0 +X 710 . G <*> 0 . DP=29;I16=5,23,0,0,961,34825,0,0,1618,95282,0,0,533,12029,0,0;QS=3,0;MQSB=0.864394;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,174:8:0 0,15,122:5:0 +X 711 . A <*> 0 . DP=29;I16=6,23,0,0,996,35700,0,0,1647,96123,0,0,565,12723,0,0;QS=3,0;MQSB=0.957107;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,171:7:0 0,18,142:6:0 +X 712 . C <*> 0 . DP=29;I16=6,23,0,0,1069,40863,0,0,1647,96123,0,0,565,12767,0,0;QS=3,0;MQSB=0.957107;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,156:7:0 0,18,146:6:0 +X 713 . T <*> 0 . DP=29;I16=6,23,0,0,1072,40426,0,0,1647,96123,0,0,565,12835,0,0;QS=3,0;MQSB=0.957107;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,187:7:0 0,18,149:6:0 +X 714 . C <*> 0 . DP=28;I16=6,21,0,0,988,37236,0,0,1558,91682,0,0,541,12301,0,0;QS=3,0;MQSB=0.90877;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,153:6:0 0,15,125:5:0 +X 715 . A <*> 0 . DP=28;I16=6,20,0,0,884,31414,0,0,1498,88082,0,0,522,12004,0,0;QS=3,0;MQSB=0.913254;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,138:6:0 0,15,120:5:0 +X 716 . C <*> 0 . DP=29;I16=4,23,0,0,998,37756,0,0,1527,88923,0,0,547,12501,0,0;QS=3,0;MQSB=0.877203;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,141:5:0 0,18,145:6:0 +X 717 . A <*> 0 . DP=31;I16=8,23,0,0,1136,42928,0,0,1767,103323,0,0,574,13254,0,0;QS=3,0;MQSB=0.987595;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,212:8:0 0,18,153:6:0 +X 718 . G <*> 0 . DP=29;I16=7,22,0,0,1066,40006,0,0,1647,96123,0,0,579,13407,0,0;QS=3,0;MQSB=0.979435;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,223:8:0 0,18,139:6:0 +X 719 . G <*> 0 . DP=29;I16=7,19,0,0,952,35868,0,0,1529,90841,0,0,510,11756,0,0;QS=3,0;MQSB=0.860025;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,204:8:0 0,12,120:4:0 +X 720 . G <*> 0 . DP=28;I16=6,20,0,0,986,37838,0,0,1467,85323,0,0,552,12940,0,0;QS=3,0;MQSB=0.970805;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,216:8:0 0,18,147:6:0 +X 721 . C <*> 0 . DP=28;I16=6,21,0,0,989,36901,0,0,1527,88923,0,0,567,13183,0,0;QS=3,0;MQSB=0.966147;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,197:8:0 0,18,147:6:0 +X 722 . A <*> 0 . DP=28;I16=6,21,0,0,949,33837,0,0,1527,88923,0,0,569,13225,0,0;QS=3,0;MQSB=0.966147;MQ0F=0 PL:DP:DV 0,39,244:13:0 0,24,205:8:0 0,18,143:6:0 +X 723 . A <*> 0 . DP=28;I16=6,19,0,0,925,34825,0,0,1438,84482,0,0,530,12366,0,0;QS=3,0;MQSB=0.918029;MQ0F=0 PL:DP:DV 0,36,253:12:0 0,24,206:8:0 0,15,135:5:0 +X 724 . C <*> 0 . DP=28;I16=5,22,0,0,967,35983,0,0,1527,88923,0,0,566,13028,0,0;QS=3,0;MQSB=0.932273;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,161:7:0 0,18,140:6:0 +X 725 . A <*> 0 . DP=28;I16=6,21,0,0,911,31971,0,0,1527,88923,0,0,565,12987,0,0;QS=3,0;MQSB=0.966147;MQ0F=0 PL:DP:DV 0,42,246:14:0 0,21,168:7:0 0,18,137:6:0 +X 726 . C <*> 0 . DP=28;I16=6,21,0,0,947,34531,0,0,1527,88923,0,0,563,12919,0,0;QS=3,0;MQSB=0.966147;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,166:7:0 0,18,136:6:0 +X 727 . A C,<*> 0 . DP=28;I16=6,20,0,1,904,32194,17,289,1498,88082,29,841,535,12199,25,625;QS=2.90811,0.0918919,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.966147;BQB=1;MQ0F=0 PL:DP:DV 0,42,247,42,247,247:14:0 0,21,191,21,191,191:7:0 0,1,109,15,112,119:6:1 +X 728 . C <*> 0 . DP=29;I16=6,22,0,0,1018,37990,0,0,1587,92523,0,0,557,12701,0,0;QS=3,0;MQSB=0.961573;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,208:8:0 0,18,142:6:0 +X 729 . T <*> 0 . DP=29;I16=7,22,0,0,1063,39315,0,0,1647,96123,0,0,581,13227,0,0;QS=3,0;MQSB=0.979435;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,244:9:0 0,18,142:6:0 +X 730 . A <*> 0 . DP=29;I16=7,21,0,0,993,35883,0,0,1618,95282,0,0,555,12529,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,219:9:0 0,15,135:5:0 +X 731 . T <*> 0 . DP=29;I16=7,22,0,0,1024,37312,0,0,1647,96123,0,0,578,13058,0,0;QS=3,0;MQSB=0.979435;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,210:9:0 0,18,148:6:0 +X 732 . C <*> 0 . DP=29;I16=7,21,0,0,1006,37058,0,0,1618,95282,0,0,550,12314,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,219:9:0 0,15,129:5:0 +X 733 . T <*> 0 . DP=29;I16=7,21,0,0,985,35497,0,0,1618,95282,0,0,547,12221,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,222:9:0 0,15,134:5:0 +X 734 . G <*> 0 . DP=29;I16=7,21,0,0,997,36453,0,0,1587,92523,0,0,544,12154,0,0;QS=3,0;MQSB=0.982906;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,204:8:0 0,18,139:6:0 +X 735 . A <*> 0 . DP=30;I16=7,21,0,0,963,33993,0,0,1618,95282,0,0,515,11437,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,190:8:0 0,18,148:6:0 +X 736 . C <*> 0 . DP=30;I16=8,20,0,0,1042,39326,0,0,1618,95282,0,0,512,11320,0,0;QS=3,0;MQSB=0.954515;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,218:8:0 0,18,152:6:0 +X 737 . T <*> 0 . DP=30;I16=8,22,0,0,1071,39825,0,0,1707,99723,0,0,560,12480,0,0;QS=3,0;MQSB=0.990151;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,243:9:0 0,21,149:7:0 +X 738 . G <*> 0 . DP=30;I16=8,21,0,0,1016,36816,0,0,1678,98882,0,0,533,11793,0,0;QS=3,0;MQSB=0.950946;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,210:9:0 0,18,141:6:0 +X 739 . T <*> 0 . DP=30;I16=7,22,0,0,1020,37326,0,0,1647,96123,0,0,534,11900,0,0;QS=3,0;MQSB=0.979435;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,202:8:0 0,21,155:7:0 +X 740 . T <*> 0 . DP=29;I16=7,21,0,0,1011,37465,0,0,1587,92523,0,0,532,11848,0,0;QS=3,0;MQSB=0.982906;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,232:8:0 0,21,155:7:0 +X 741 . T <*> 0 . DP=29;I16=7,21,0,0,984,36052,0,0,1587,92523,0,0,528,11722,0,0;QS=3,0;MQSB=0.982906;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,224:8:0 0,21,151:7:0 +X 742 . C <*> 0 . DP=30;I16=8,21,0,0,1046,39056,0,0,1678,98882,0,0,525,11671,0,0;QS=3,0;MQSB=0.950946;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,243:9:0 0,18,136:6:0 +X 743 . A <*> 0 . DP=30;I16=8,21,0,0,1026,37156,0,0,1678,98882,0,0,520,11500,0,0;QS=3,0;MQSB=0.950946;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,239:9:0 0,18,131:6:0 +X 744 . T <*> 0 . DP=30;I16=8,22,0,0,1100,41010,0,0,1707,99723,0,0,540,11984,0,0;QS=3,0;MQSB=0.990151;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,247:9:0 0,21,154:7:0 +X 745 . G <*> 0 . DP=31;I16=9,22,0,0,1078,38890,0,0,1767,103323,0,0,535,11873,0,0;QS=3,0;MQSB=0.996219;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,227:9:0 0,24,178:8:0 +X 746 . G <*> 0 . DP=31;I16=9,21,0,0,1001,35191,0,0,1707,99723,0,0,531,11793,0,0;QS=3,0;MQSB=0.997698;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,201:9:0 0,24,178:8:0 +X 747 . G <*> 0 . DP=30;I16=9,20,0,0,1017,36831,0,0,1647,96123,0,0,509,11343,0,0;QS=3,0;MQSB=0.99889;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,201:8:0 0,21,174:7:0 +X 748 . A <*> 0 . DP=30;I16=10,20,0,0,1046,37438,0,0,1707,99723,0,0,529,11721,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,242:9:0 0,18,159:6:0 +X 749 . A <*> 0 . DP=31;I16=10,21,0,0,1077,38303,0,0,1767,103323,0,0,530,11728,0,0;QS=3,0;MQSB=0.999777;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,27,240:9:0 0,18,164:6:0 +X 750 . A <*> 0 . DP=32;I16=10,20,0,0,1129,43093,0,0,1738,102482,0,0,500,11252,0,0;QS=3,0;MQSB=0.976097;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,232:8:0 0,15,161:5:0 +X 751 . G <*> 0 . DP=31;I16=11,20,0,0,1065,37955,0,0,1767,103323,0,0,535,11787,0,0;QS=3,0;MQSB=0.999148;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,27,206:9:0 0,18,150:6:0 +X 752 . T <*> 0 . DP=31;I16=11,20,0,0,1034,35786,0,0,1767,103323,0,0,537,11793,0,0;QS=3,0;MQSB=0.999148;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,27,223:9:0 0,18,143:6:0 +X 753 . C <*> 0 . DP=31;I16=12,19,0,0,1073,38779,0,0,1767,103323,0,0,540,11834,0,0;QS=3,0;MQSB=0.994873;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,30,227:10:0 0,18,158:6:0 +X 754 . T <*> 0 . DP=31;I16=12,19,0,0,1135,42527,0,0,1767,103323,0,0,542,11808,0,0;QS=3,0;MQSB=0.994873;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,30,255:10:0 0,18,172:6:0 +X 755 . G <*> 0 . DP=31;I16=12,19,0,0,1157,43695,0,0,1767,103323,0,0,544,11814,0,0;QS=3,0;MQSB=0.994873;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,30,255:10:0 0,18,162:6:0 +X 756 . G <*> 0 . DP=30;I16=12,17,0,0,1002,35566,0,0,1647,96123,0,0,539,11753,0,0;QS=3,0;MQSB=0.988062;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,30,242:10:0 0,18,157:6:0 +X 757 . A <*> 0 . DP=30;I16=12,17,0,0,1035,37723,0,0,1678,98882,0,0,523,11197,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,30,248:10:0 0,15,152:5:0 +X 758 . A <*> 0 . DP=30;I16=12,18,0,0,1015,35685,0,0,1707,99723,0,0,549,11825,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,30,247:10:0 0,18,156:6:0 +X 759 . A <*> 0 . DP=30;I16=12,16,0,0,998,36498,0,0,1618,95282,0,0,526,11472,0,0;QS=3,0;MQSB=0.995699;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,242:9:0 0,15,151:5:0 +X 760 . C <*> 0 . DP=31;I16=12,18,0,0,916,29466,0,0,1707,99723,0,0,547,11741,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,30,217:10:0 0,18,128:6:0 +X 761 . G <*> 0 . DP=30;I16=11,16,0,0,932,32884,0,0,1589,94441,0,0,512,11028,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,220:9:0 0,15,153:5:0 +X 762 . G <*> 0 . DP=29;I16=11,18,0,0,1012,36984,0,0,1647,96123,0,0,541,11629,0,0;QS=3,0;MQSB=0.995968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,220:9:0 0,21,173:7:0 +X 763 . C A,<*> 0 . DP=29;I16=11,16,0,1,948,35124,15,225,1558,91682,29,841,527,11473,2,4;QS=2.93697,0.0630252,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.993109;BQB=1;MQ0F=0 PL:DP:DV 0,39,255,39,255,255:13:0 0,24,193,24,193,193:8:0 0,6,158,18,161,165:7:1 +X 764 . A <*> 0 . DP=31;I16=12,18,0,0,1051,37737,0,0,1738,102482,0,0,516,11020,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,30,250:10:0 0,18,163:6:0 +X 765 . A <*> 0 . DP=32;I16=12,18,0,0,1071,39369,0,0,1738,102482,0,0,525,11379,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,30,254:10:0 0,18,169:6:0 +X 766 . C <*> 0 . DP=31;I16=13,18,0,0,1065,38285,0,0,1798,106082,0,0,547,11797,0,0;QS=3,0;MQSB=0.995005;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,33,235:11:0 0,18,164:6:0 +X 767 . A <*> 0 . DP=30;I16=12,18,0,0,996,34692,0,0,1738,102482,0,0,552,11926,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,244:11:0 0,18,148:6:0 +X 768 . C <*> 0 . DP=30;I16=12,18,0,0,1095,40739,0,0,1738,102482,0,0,556,12038,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,255:11:0 0,18,173:6:0 +X 769 . C <*> 0 . DP=30;I16=12,18,0,0,1110,42272,0,0,1738,102482,0,0,559,12133,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,255:11:0 0,18,173:6:0 +X 770 . A <*> 0 . DP=30;I16=12,18,0,0,1098,40852,0,0,1738,102482,0,0,562,12262,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,255:11:0 0,18,171:6:0 +X 771 . T <*> 0 . DP=30;I16=12,18,0,0,1111,41771,0,0,1738,102482,0,0,563,12325,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,255:11:0 0,18,177:6:0 +X 772 . T <*> 0 . DP=30;I16=12,18,0,0,1107,41429,0,0,1738,102482,0,0,563,12373,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,255:11:0 0,18,176:6:0 +X 773 . G <*> 0 . DP=30;I16=12,18,0,0,1123,42761,0,0,1738,102482,0,0,562,12406,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,255:11:0 0,18,175:6:0 +X 774 . A <*> 0 . DP=30;I16=12,18,0,0,1151,44801,0,0,1738,102482,0,0,560,12422,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,255:11:0 0,18,179:6:0 +X 775 . G <*> 0 . DP=30;I16=12,18,0,0,1136,43766,0,0,1738,102482,0,0,557,12419,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,255:11:0 0,18,177:6:0 +X 776 . A <*> 0 . DP=29;I16=12,17,0,0,1053,38865,0,0,1678,98882,0,0,553,12345,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,30,255:10:0 0,18,169:6:0 +X 777 . C <*> 0 . DP=28;I16=12,16,0,0,1019,37631,0,0,1618,95282,0,0,550,12298,0,0;QS=3,0;MQSB=0.995699;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,229:9:0 0,18,165:6:0 +X 778 . A <*> 0 . DP=28;I16=12,16,0,0,1079,42041,0,0,1618,95282,0,0,547,12277,0,0;QS=3,0;MQSB=0.995699;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,241:9:0 0,18,181:6:0 +X 779 . G <*> 0 . DP=28;I16=12,16,0,0,1025,38825,0,0,1618,95282,0,0,543,12231,0,0;QS=3,0;MQSB=0.995699;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,231:9:0 0,18,170:6:0 +X 780 . A <*> 0 . DP=28;I16=12,16,0,0,1005,36773,0,0,1618,95282,0,0,538,12160,0,0;QS=3,0;MQSB=0.995699;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,242:9:0 0,18,166:6:0 +X 781 . A <*> 0 . DP=28;I16=12,15,0,0,965,35857,0,0,1589,94441,0,0,519,11889,0,0;QS=3,0;MQSB=0.935229;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,222:8:0 0,15,159:5:0 +X 782 . A <*> 0 . DP=28;I16=12,16,0,0,1003,37315,0,0,1618,95282,0,0,530,12044,0,0;QS=3,0;MQSB=0.995699;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,229:8:0 0,18,171:6:0 +X 783 . A <*> 0 . DP=28;I16=12,16,0,0,989,36477,0,0,1618,95282,0,0,527,12001,0,0;QS=3,0;MQSB=0.995699;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,230:8:0 0,21,178:7:0 +X 784 . C <*> 0 . DP=26;I16=11,15,0,0,967,36387,0,0,1498,88082,0,0,527,11983,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,207:7:0 0,21,178:7:0 +X 785 . A <*> 0 . DP=26;I16=11,15,0,0,989,38499,0,0,1498,88082,0,0,527,11989,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,213:7:0 0,21,187:7:0 +X 786 . G <*> 0 . DP=26;I16=11,14,0,0,938,35698,0,0,1438,84482,0,0,501,11343,0,0;QS=3,0;MQSB=0.996634;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,211:7:0 0,21,180:7:0 +X 787 . G <*> 0 . DP=26;I16=11,15,0,0,914,33428,0,0,1498,88082,0,0,525,11969,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,189:7:0 0,21,175:7:0 +X 788 . T <*> 0 . DP=26;I16=11,15,0,0,913,33357,0,0,1498,88082,0,0,524,11992,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,180:7:0 0,21,188:7:0 +X 789 . G <*> 0 . DP=26;I16=11,15,0,0,963,36645,0,0,1498,88082,0,0,523,12037,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,193:7:0 0,21,183:7:0 +X 790 . A <*> 0 . DP=26;I16=11,15,0,0,999,39113,0,0,1498,88082,0,0,520,12002,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,198:7:0 0,21,201:7:0 +X 791 . G <*> 0 . DP=26;I16=11,15,0,0,934,34208,0,0,1498,88082,0,0,516,11934,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,180:7:0 0,21,172:7:0 +X 792 . T <*> 0 . DP=26;I16=11,15,0,0,895,32009,0,0,1498,88082,0,0,511,11833,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,184:7:0 0,21,172:7:0 +X 793 . G <*> 0 . DP=27;I16=11,15,0,0,965,36389,0,0,1498,88082,0,0,504,11652,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,193:7:0 0,21,170:7:0 +X 794 . G <*> 0 . DP=26;I16=11,15,0,0,888,31804,0,0,1498,88082,0,0,508,11592,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,198:8:0 0,18,161:6:0 +X 795 . T <*> 0 . DP=26;I16=9,15,0,0,859,31399,0,0,1409,83641,0,0,472,10908,0,0;QS=3,0;MQSB=0.96464;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,211:7:0 0,18,160:6:0 +X 796 . T <*> 0 . DP=27;I16=11,16,0,0,907,31641,0,0,1558,91682,0,0,499,11375,0,0;QS=3,0;MQSB=0.992419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,221:9:0 0,15,150:5:0 +X 797 . G <*> 0 . DP=26;I16=11,15,0,0,882,31700,0,0,1529,90841,0,0,498,11298,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,215:9:0 0,12,135:4:0 +X 798 . C <*> 0 . DP=26;I16=9,15,0,0,806,28552,0,0,1440,86400,0,0,466,10582,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,207:8:0 0,12,126:4:0 +X 799 . C <*> 0 . DP=26;I16=10,15,0,0,947,36407,0,0,1500,90000,0,0,491,11185,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,234:9:0 0,12,137:4:0 +X 800 . T <*> 0 . DP=26;I16=11,15,0,0,993,38475,0,0,1529,90841,0,0,495,11199,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,255:9:0 0,12,139:4:0 +X 801 . G <*> 0 . DP=25;I16=11,14,0,0,938,35854,0,0,1469,87241,0,0,495,11209,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,240:9:0 0,12,145:4:0 +X 802 . G <*> 0 . DP=25;I16=11,14,0,0,892,32802,0,0,1469,87241,0,0,495,11239,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,229:9:0 0,12,137:4:0 +X 803 . G <*> 0 . DP=25;I16=11,14,0,0,906,33502,0,0,1469,87241,0,0,495,11289,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,237:9:0 0,12,136:4:0 +X 804 . G <*> 0 . DP=25;I16=11,12,0,0,868,33326,0,0,1349,80041,0,0,466,10846,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,223:8:0 0,12,138:4:0 +X 805 . C <*> 0 . DP=24;I16=9,14,0,0,810,29684,0,0,1380,82800,0,0,482,11208,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,220:8:0 0,12,128:4:0 +X 806 . C <*> 0 . DP=25;I16=9,14,0,0,814,29856,0,0,1380,82800,0,0,483,11293,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,214:8:0 0,12,122:4:0 +X 807 . A <*> 0 . DP=25;I16=10,15,0,0,939,35997,0,0,1500,90000,0,0,503,11525,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,242:9:0 0,12,146:4:0 +X 808 . G <*> 0 . DP=25;I16=10,15,0,0,918,34720,0,0,1500,90000,0,0,505,11591,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,238:9:0 0,12,136:4:0 +X 809 . G <*> 0 . DP=25;I16=10,15,0,0,926,34932,0,0,1500,90000,0,0,506,11626,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,226:9:0 0,12,136:4:0 +X 810 . G C,<*> 0 . DP=25;I16=10,13,0,1,824,30436,14,196,1380,82800,60,3600,480,11288,14,196;QS=2.96552,0.0344828,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,21,255,33,255,255:12:1 0,24,216,24,216,216:8:0 0,12,132,12,132,132:4:0 +X 811 . A <*> 0 . DP=25;I16=9,14,0,0,808,29404,0,0,1380,82800,0,0,484,11294,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,204:7:0 0,12,139:4:0 +X 812 . A <*> 0 . DP=25;I16=10,15,0,0,831,29515,0,0,1500,90000,0,0,500,11392,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,216:9:0 0,12,139:4:0 +X 813 . C <*> 0 . DP=25;I16=10,15,0,0,915,34093,0,0,1500,90000,0,0,497,11307,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,239:9:0 0,12,138:4:0 +X 814 . T <*> 0 . DP=25;I16=10,15,0,0,987,39343,0,0,1500,90000,0,0,494,11244,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,255:9:0 0,12,148:4:0 +X 815 . T <*> 0 . DP=25;I16=10,15,0,0,894,32670,0,0,1500,90000,0,0,491,11203,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,235:9:0 0,12,143:4:0 +X 816 . T <*> 0 . DP=25;I16=10,15,0,0,898,32990,0,0,1500,90000,0,0,488,11184,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,239:9:0 0,12,136:4:0 +X 817 . C <*> 0 . DP=24;I16=10,14,0,0,898,34256,0,0,1440,86400,0,0,485,11137,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,235:9:0 0,12,124:4:0 +X 818 . T <*> 0 . DP=23;I16=9,14,0,0,883,34371,0,0,1380,82800,0,0,484,11110,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,225:8:0 0,12,143:4:0 +X 819 . G <*> 0 . DP=23;I16=9,13,0,0,832,31932,0,0,1320,79200,0,0,461,10573,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,217:8:0 0,12,142:4:0 +X 820 . G <*> 0 . DP=24;I16=10,14,0,0,844,30848,0,0,1440,86400,0,0,484,11114,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,230:9:0 0,12,135:4:0 +X 821 . G <*> 0 . DP=24;I16=10,14,0,0,852,31572,0,0,1440,86400,0,0,484,11098,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,234:9:0 0,12,142:4:0 +X 822 . G <*> 0 . DP=25;I16=10,15,0,0,879,31785,0,0,1500,90000,0,0,481,10955,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,220:9:0 0,12,127:4:0 +X 823 . T <*> 0 . DP=25;I16=10,15,0,0,844,29686,0,0,1500,90000,0,0,478,10786,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,217:9:0 0,12,127:4:0 +X 824 . C <*> 0 . DP=25;I16=9,14,0,0,824,30252,0,0,1380,82800,0,0,427,9477,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,215:9:0 0,9,98:3:0 +X 825 . A <*> 0 . DP=25;I16=10,15,0,0,881,31665,0,0,1500,90000,0,0,467,10277,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,234:9:0 0,12,116:4:0 +X 826 . T <*> 0 . DP=25;I16=10,15,0,0,826,28364,0,0,1500,90000,0,0,461,10039,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,250:12:0 0,27,232:9:0 0,12,117:4:0 +X 827 . A <*> 0 . DP=25;I16=10,15,0,0,851,29477,0,0,1500,90000,0,0,455,9829,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,227:9:0 0,12,123:4:0 +X 828 . T C,<*> 0 . DP=25;I16=2,4,8,11,199,6917,656,23340,360,21600,1140,68400,116,2716,333,6931;QS=0.597777,2.40222,0;VDB=0.842082;SGB=-4.20907;RPB=0.950652;MQB=1;MQSB=1;BQB=0.929717;MQ0F=0 PL:DP:DV 211,0,35,217,65,255:12:10 116,0,91,128,106,213:9:5 120,12,0,120,12,120:4:4 +X 829 . T <*> 0 . DP=24;I16=10,13,0,0,863,32931,0,0,1380,82800,0,0,418,8818,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,242:8:0 0,12,132:4:0 +X 830 . C <*> 0 . DP=24;I16=10,14,0,0,910,34966,0,0,1440,86400,0,0,437,9267,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,220:8:0 0,12,134:4:0 +X 831 . T <*> 0 . DP=24;I16=10,14,0,0,906,34886,0,0,1440,86400,0,0,431,9119,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,243:8:0 0,12,133:4:0 +X 832 . C <*> 0 . DP=24;I16=10,14,0,0,888,33634,0,0,1440,86400,0,0,425,8999,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,220:8:0 0,12,123:4:0 +X 833 . T <*> 0 . DP=25;I16=10,14,0,0,820,29920,0,0,1440,86400,0,0,418,8856,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,224:8:0 0,12,113:4:0 +X 834 . G A,<*> 0 . DP=25;I16=2,3,7,10,164,5898,590,21124,300,18000,1020,61200,104,2296,305,6441;QS=0.520056,2.47994,0;VDB=0.788006;SGB=-4.01214;RPB=0.999233;MQB=1;MQSB=1;BQB=0.821668;MQ0F=0 PL:DP:DV 185,0,46,191,73,246:11:9 128,0,59,137,74,193:8:5 89,9,0,89,9,89:3:3 +X 835 . T <*> 0 . DP=26;I16=9,15,0,0,767,26675,0,0,1440,86400,0,0,406,8652,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,240:12:0 0,24,213:8:0 0,12,98:4:0 +X 836 . G <*> 0 . DP=23;I16=8,15,0,0,833,30561,0,0,1380,82800,0,0,403,8541,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,243:11:0 0,24,214:8:0 0,12,130:4:0 +X 837 . T <*> 0 . DP=23;I16=8,15,0,0,843,31499,0,0,1380,82800,0,0,400,8456,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,241:11:0 0,24,221:8:0 0,12,143:4:0 +X 838 . T <*> 0 . DP=23;I16=8,15,0,0,870,33172,0,0,1380,82800,0,0,397,8397,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,252:11:0 0,24,224:8:0 0,12,134:4:0 +X 839 . G <*> 0 . DP=24;I16=8,15,0,0,862,32774,0,0,1380,82800,0,0,393,8315,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,249:11:0 0,24,212:8:0 0,12,142:4:0 +X 840 . A <*> 0 . DP=25;I16=9,15,0,0,876,32682,0,0,1440,86400,0,0,375,7731,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,243:11:0 0,21,196:7:0 0,18,180:6:0 +X 841 . T <*> 0 . DP=25;I16=9,16,0,0,861,30879,0,0,1500,90000,0,0,396,8260,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,213:11:0 0,24,226:8:0 0,18,185:6:0 +X 842 . T <*> 0 . DP=24;I16=9,15,0,0,872,31990,0,0,1440,86400,0,0,393,8199,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,227:10:0 0,24,231:8:0 0,18,175:6:0 +X 843 . C <*> 0 . DP=24;I16=9,15,0,0,844,30604,0,0,1440,86400,0,0,390,8172,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,228:10:0 0,24,229:8:0 0,18,160:6:0 +X 844 . T <*> 0 . DP=24;I16=9,15,0,0,900,34094,0,0,1440,86400,0,0,386,8128,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,227:10:0 0,24,238:8:0 0,18,189:6:0 +X 845 . G <*> 0 . DP=25;I16=10,15,0,0,916,33866,0,0,1500,90000,0,0,382,8116,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,239:10:0 0,24,225:8:0 0,21,196:7:0 +X 846 . G <*> 0 . DP=24;I16=9,14,0,0,802,28414,0,0,1380,82800,0,0,354,7460,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,223:9:0 0,24,208:8:0 0,18,164:6:0 +X 847 . T <*> 0 . DP=24;I16=8,15,0,0,809,29007,0,0,1380,82800,0,0,377,8083,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,210:9:0 0,24,219:8:0 0,18,149:6:0 +X 848 . G <*> 0 . DP=23;I16=8,15,0,0,829,30351,0,0,1380,82800,0,0,384,8138,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,199:8:0 0,27,243:9:0 0,18,167:6:0 +X 849 . G <*> 0 . DP=22;I16=8,12,0,0,684,23844,0,0,1200,72000,0,0,349,7517,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,160:6:0 0,27,233:9:0 0,15,140:5:0 +X 850 . T <*> 0 . DP=21;I16=6,14,0,0,706,25508,0,0,1200,72000,0,0,360,7568,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,153:6:0 0,24,226:8:0 0,18,147:6:0 +X 851 . G <*> 0 . DP=21;I16=7,14,0,0,707,24667,0,0,1260,75600,0,0,386,8254,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,140:6:0 0,27,233:9:0 0,18,156:6:0 +X 852 . G <*> 0 . DP=21;I16=7,13,0,0,687,24223,0,0,1200,72000,0,0,368,7976,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,147:6:0 0,27,222:9:0 0,15,146:5:0 +X 853 . A <*> 0 . DP=21;I16=7,14,0,0,721,25603,0,0,1260,75600,0,0,388,8442,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,146:6:0 0,27,223:9:0 0,18,166:6:0 +X 854 . A <*> 0 . DP=21;I16=7,14,0,0,725,25843,0,0,1260,75600,0,0,389,8517,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,179:7:0 0,24,209:8:0 0,18,168:6:0 +X 855 . A <*> 0 . DP=21;I16=7,14,0,0,683,23803,0,0,1260,75600,0,0,391,8611,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,171:7:0 0,24,204:8:0 0,18,152:6:0 +X 856 . C <*> 0 . DP=21;I16=7,14,0,0,763,28293,0,0,1260,75600,0,0,392,8676,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,192:7:0 0,24,222:8:0 0,18,172:6:0 +X 857 . A <*> 0 . DP=22;I16=8,14,0,0,786,28480,0,0,1320,79200,0,0,393,8763,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,182:7:0 0,24,220:8:0 0,21,194:7:0 +X 858 . A <*> 0 . DP=22;I16=8,14,0,0,816,31358,0,0,1320,79200,0,0,395,8873,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,192:7:0 0,24,236:8:0 0,21,198:7:0 +X 859 . G <*> 0 . DP=22;I16=8,14,0,0,824,31356,0,0,1320,79200,0,0,395,8907,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,202:7:0 0,24,223:8:0 0,21,203:7:0 +X 860 . A <*> 0 . DP=22;I16=8,13,0,0,743,26985,0,0,1260,75600,0,0,369,8291,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,184:7:0 0,21,202:7:0 0,21,190:7:0 +X 861 . C <*> 0 . DP=22;I16=8,14,0,0,770,28376,0,0,1320,79200,0,0,393,8899,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,206:8:0 0,24,216:8:0 0,18,161:6:0 +X 862 . T <*> 0 . DP=22;I16=8,14,0,0,762,27500,0,0,1320,79200,0,0,393,8905,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,188:8:0 0,24,213:8:0 0,18,177:6:0 +X 863 . G <*> 0 . DP=23;I16=9,14,0,0,836,30660,0,0,1380,82800,0,0,393,8935,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,24,221:8:0 0,18,180:6:0 +X 864 . T <*> 0 . DP=22;I16=9,13,0,0,795,29085,0,0,1320,79200,0,0,395,8989,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,215:8:0 0,24,221:8:0 0,18,180:6:0 +X 865 . C <*> 0 . DP=22;I16=8,14,0,0,785,28475,0,0,1320,79200,0,0,397,9015,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,21,193:7:0 0,18,177:6:0 +X 866 . C <*> 0 . DP=21;I16=7,13,0,0,694,24890,0,0,1200,72000,0,0,395,8985,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,220:8:0 0,18,149:6:0 0,18,177:6:0 +X 867 . C <*> 0 . DP=21;I16=7,14,0,0,761,28443,0,0,1260,75600,0,0,403,9023,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,223:9:0 0,18,182:6:0 0,18,187:6:0 +X 868 . A <*> 0 . DP=21;I16=7,14,0,0,799,31183,0,0,1260,75600,0,0,406,9054,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,18,189:6:0 0,18,202:6:0 +X 869 . G <*> 0 . DP=21;I16=7,14,0,0,795,30733,0,0,1260,75600,0,0,409,9103,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,236:9:0 0,18,190:6:0 0,18,187:6:0 +X 870 . C <*> 0 . DP=21;I16=7,13,0,0,758,29080,0,0,1200,72000,0,0,403,9089,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,226:8:0 0,18,183:6:0 0,18,187:6:0 +X 871 . C <*> 0 . DP=21;I16=7,14,0,0,769,29383,0,0,1260,75600,0,0,413,9155,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,232:9:0 0,18,176:6:0 0,18,192:6:0 +X 872 . T <*> 0 . DP=21;I16=7,14,0,0,785,29879,0,0,1260,75600,0,0,413,9109,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,18,187:6:0 0,18,188:6:0 +X 873 . G <*> 0 . DP=21;I16=7,14,0,0,768,28506,0,0,1260,75600,0,0,413,9083,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,18,172:6:0 0,18,182:6:0 +X 874 . G <*> 0 . DP=21;I16=7,12,0,0,700,26434,0,0,1140,68400,0,0,374,8234,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,227:8:0 0,15,143:5:0 0,18,189:6:0 +X 875 . G <*> 0 . DP=21;I16=7,14,0,0,717,25659,0,0,1260,75600,0,0,411,8995,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,18,163:6:0 0,18,159:6:0 +X 876 . T <*> 0 . DP=21;I16=7,14,0,0,719,25261,0,0,1260,75600,0,0,410,8984,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,222:9:0 0,18,156:6:0 0,18,173:6:0 +X 877 . G <*> 0 . DP=21;I16=7,14,0,0,747,27419,0,0,1260,75600,0,0,409,8995,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,235:9:0 0,18,162:6:0 0,18,176:6:0 +X 878 . A <*> 0 . DP=21;I16=7,13,0,0,738,27650,0,0,1200,72000,0,0,391,8739,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,216:8:0 0,18,172:6:0 0,18,191:6:0 +X 879 . T <*> 0 . DP=21;I16=7,13,0,0,731,26927,0,0,1200,72000,0,0,389,8759,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,214:8:0 0,18,175:6:0 0,18,184:6:0 +X 880 . A <*> 0 . DP=21;I16=7,14,0,0,737,26481,0,0,1260,75600,0,0,405,9109,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,18,165:6:0 0,18,172:6:0 +X 881 . C <*> 0 . DP=20;I16=7,13,0,0,742,27898,0,0,1200,72000,0,0,404,9154,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,231:8:0 0,18,164:6:0 0,18,183:6:0 +X 882 . A <*> 0 . DP=20;I16=7,13,0,0,776,30564,0,0,1200,72000,0,0,403,9217,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,225:8:0 0,18,188:6:0 0,18,200:6:0 +X 883 . G <*> 0 . DP=20;I16=7,13,0,0,702,25898,0,0,1200,72000,0,0,401,9247,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,214:8:0 0,18,175:6:0 0,18,176:6:0 +X 884 . C <*> 0 . DP=19;I16=7,12,0,0,629,21449,0,0,1140,68400,0,0,400,9292,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,201:8:0 0,18,155:6:0 0,15,144:5:0 +X 885 . G <*> 0 . DP=18;I16=7,11,0,0,605,20851,0,0,1080,64800,0,0,400,9350,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,215:8:0 0,15,140:5:0 0,15,130:5:0 +X 886 . A <*> 0 . DP=18;I16=7,11,0,0,681,26145,0,0,1080,64800,0,0,400,9420,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,222:8:0 0,15,164:5:0 0,15,163:5:0 +X 887 . G <*> 0 . DP=18;I16=7,11,0,0,631,22891,0,0,1080,64800,0,0,399,9451,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,222:8:0 0,15,138:5:0 0,15,149:5:0 +X 888 . A <*> 0 . DP=18;I16=7,10,0,0,593,21563,0,0,1020,61200,0,0,373,8867,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,216:8:0 0,15,132:5:0 0,12,127:4:0 +X 889 . C <*> 0 . DP=18;I16=7,11,0,0,624,22732,0,0,1080,64800,0,0,396,9492,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,213:8:0 0,15,134:5:0 0,15,160:5:0 +X 890 . C <*> 0 . DP=19;I16=7,11,0,0,616,22426,0,0,1080,64800,0,0,368,8826,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,215:8:0 0,15,138:5:0 0,15,152:5:0 +X 891 . C <*> 0 . DP=19;I16=7,11,0,0,661,24891,0,0,1080,64800,0,0,365,8745,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,227:8:0 0,15,141:5:0 0,15,165:5:0 +X 892 . C <*> 0 . DP=19;I16=7,12,0,0,691,25761,0,0,1140,68400,0,0,387,9299,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,230:9:0 0,15,146:5:0 0,15,167:5:0 +X 893 . A <*> 0 . DP=19;I16=7,12,0,0,673,24521,0,0,1140,68400,0,0,384,9238,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,221:9:0 0,15,142:5:0 0,15,166:5:0 +X 894 . T <*> 0 . DP=19;I16=7,12,0,0,670,24268,0,0,1140,68400,0,0,380,9138,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,225:9:0 0,15,134:5:0 0,15,165:5:0 +X 895 . C <*> 0 . DP=20;I16=8,12,0,0,712,26186,0,0,1200,72000,0,0,376,9050,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,15,149:5:0 0,15,162:5:0 +X 896 . T <*> 0 . DP=19;I16=8,10,0,0,684,26696,0,0,1080,64800,0,0,348,8300,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,12,141:4:0 0,15,180:5:0 +X 897 . C <*> 0 . DP=18;I16=8,10,0,0,693,27001,0,0,1080,64800,0,0,370,8764,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,12,131:4:0 0,15,166:5:0 +X 898 . T <*> 0 . DP=18;I16=8,10,0,0,674,25656,0,0,1080,64800,0,0,367,8617,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,243:9:0 0,12,125:4:0 0,15,172:5:0 +X 899 . A <*> 0 . DP=18;I16=9,8,0,0,597,21451,0,0,1020,61200,0,0,340,7858,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,9,99:3:0 0,15,145:5:0 +X 900 . C <*> 0 . DP=18;I16=9,9,0,0,658,24550,0,0,1080,64800,0,0,364,8362,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,98:3:0 0,15,166:5:0 +X 901 . C <*> 0 . DP=18;I16=9,9,0,0,680,26004,0,0,1080,64800,0,0,363,8255,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,99:3:0 0,15,169:5:0 +X 902 . A <*> 0 . DP=18;I16=9,9,0,0,681,26253,0,0,1080,64800,0,0,362,8162,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,9,115:3:0 0,15,174:5:0 +X 903 . A <*> 0 . DP=18;I16=9,8,0,0,645,24625,0,0,1020,61200,0,0,336,7458,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,250:9:0 0,9,101:3:0 0,15,171:5:0 +X 904 . A <*> 0 . DP=18;I16=9,9,0,0,640,23412,0,0,1080,64800,0,0,359,7969,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,9,85:3:0 0,15,174:5:0 +X 905 . A <*> 0 . DP=18;I16=9,9,0,0,675,25673,0,0,1080,64800,0,0,357,7871,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,103:3:0 0,15,172:5:0 +X 906 . A <*> 0 . DP=18;I16=9,9,0,0,669,25193,0,0,1080,64800,0,0,355,7789,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,102:3:0 0,15,166:5:0 +X 907 . A <*> 0 . DP=18;I16=9,9,0,0,661,24541,0,0,1080,64800,0,0,353,7723,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,94:3:0 0,15,165:5:0 +X 908 . T <*> 0 . DP=18;I16=9,9,0,0,673,25579,0,0,1080,64800,0,0,351,7673,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,83:3:0 0,15,168:5:0 +X 909 . T <*> 0 . DP=18;I16=9,9,0,0,653,23847,0,0,1080,64800,0,0,348,7590,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,95:3:0 0,15,161:5:0 +X 910 . A <*> 0 . DP=18;I16=9,9,0,0,652,23790,0,0,1080,64800,0,0,344,7476,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,9,104:3:0 0,15,162:5:0 +X 911 . A <*> 0 . DP=18;I16=9,9,0,0,688,26440,0,0,1080,64800,0,0,340,7382,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,109:3:0 0,15,168:5:0 +X 912 . A <*> 0 . DP=18;I16=9,9,0,0,691,26705,0,0,1080,64800,0,0,336,7308,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,115:3:0 0,15,173:5:0 +X 913 . A <*> 0 . DP=19;I16=9,10,0,0,692,25762,0,0,1140,68400,0,0,332,7254,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,109:3:0 0,15,171:5:0 +X 914 . A <*> 0 . DP=19;I16=9,10,0,0,712,26966,0,0,1140,68400,0,0,329,7221,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,109:3:0 0,15,164:5:0 +X 915 . T <*> 0 . DP=18;I16=9,9,0,0,638,23228,0,0,1080,64800,0,0,326,7160,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,9,99:3:0 0,15,163:5:0 +X 916 . T <*> 0 . DP=19;I16=9,8,0,0,626,23136,0,0,1020,61200,0,0,296,6396,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,9,103:3:0 0,15,164:5:0 +X 917 . A <*> 0 . DP=19;I16=9,10,0,0,726,27962,0,0,1117,66169,0,0,318,6908,0,0;QS=3,0;MQSB=0.934728;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,125:4:0 0,15,171:5:0 +X 918 . G <*> 0 . DP=19;I16=9,10,0,0,688,25456,0,0,1117,66169,0,0,314,6818,0,0;QS=3,0;MQSB=0.934728;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,129:4:0 0,15,147:5:0 +X 919 . C <*> 0 . DP=18;I16=8,10,0,0,672,25786,0,0,1057,62569,0,0,311,6751,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,92:3:0 0,15,152:5:0 +X 920 . T <*> 0 . DP=18;I16=8,10,0,0,681,26113,0,0,1057,62569,0,0,308,6706,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,95:3:0 0,15,171:5:0 +X 921 . G <*> 0 . DP=17;I16=7,10,0,0,617,22841,0,0,997,58969,0,0,304,6582,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,6,47:2:0 0,15,164:5:0 +X 922 . G <*> 0 . DP=16;I16=7,8,0,0,560,21156,0,0,877,51769,0,0,276,5852,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,24,243:8:0 0,6,64:2:0 0,15,151:5:0 +X 923 . G <*> 0 . DP=16;I16=7,8,0,0,562,21350,0,0,877,51769,0,0,273,5765,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,24,245:8:0 0,6,65:2:0 0,15,144:5:0 +X 924 . C <*> 0 . DP=16;I16=7,9,0,0,603,22955,0,0,937,55369,0,0,295,6321,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,6,57:2:0 0,15,157:5:0 +X 925 . A <*> 0 . DP=16;I16=7,9,0,0,576,21618,0,0,937,55369,0,0,291,6219,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,6,58:2:0 0,15,163:5:0 +X 926 . T <*> 0 . DP=16;I16=7,9,0,0,585,22015,0,0,937,55369,0,0,287,6133,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,6,63:2:0 0,15,161:5:0 +X 927 . G <*> 0 . DP=17;I16=7,10,0,0,641,24481,0,0,997,58969,0,0,283,6063,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,9,82:3:0 0,15,158:5:0 +X 928 . G <*> 0 . DP=17;I16=7,10,0,0,625,23195,0,0,997,58969,0,0,280,6010,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,9,84:3:0 0,15,150:5:0 +X 929 . T <*> 0 . DP=16;I16=7,9,0,0,580,21580,0,0,937,55369,0,0,277,5925,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,27,248:9:0 0,9,79:3:0 0,12,128:4:0 +X 930 . G <*> 0 . DP=16;I16=7,8,0,0,565,21561,0,0,877,51769,0,0,249,5233,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,24,247:8:0 0,9,82:3:0 0,12,127:4:0 +X 931 . G <*> 0 . DP=16;I16=7,9,0,0,553,19935,0,0,937,55369,0,0,271,5809,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,9,80:3:0 0,12,113:4:0 +X 932 . T <*> 0 . DP=16;I16=7,9,0,0,558,20128,0,0,937,55369,0,0,268,5778,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,27,229:9:0 0,9,89:3:0 0,12,122:4:0 +X 933 . G <*> 0 . DP=16;I16=7,8,0,0,558,20926,0,0,877,51769,0,0,239,5091,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,24,241:8:0 0,9,94:3:0 0,12,116:4:0 +X 934 . C <*> 0 . DP=15;I16=7,8,0,0,548,20256,0,0,877,51769,0,0,261,5673,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,9,83:3:0 0,9,99:3:0 +X 935 . A <*> 0 . DP=15;I16=7,8,0,0,534,19780,0,0,846,49010,0,0,259,5647,0,0;QS=3,0;MQSB=0.720273;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,9,86:3:0 0,9,101:3:0 +X 936 . T <*> 0 . DP=15;I16=7,8,0,0,579,22499,0,0,846,49010,0,0,257,5589,0,0;QS=3,0;MQSB=0.720273;MQ0F=0 PL:DP:DV 0,27,252:9:0 0,9,91:3:0 0,9,100:3:0 +X 937 . G <*> 0 . DP=16;I16=8,7,0,0,550,20650,0,0,846,49010,0,0,232,5022,0,0;QS=3,0;MQSB=0.651439;MQ0F=0 PL:DP:DV 0,24,228:8:0 0,9,84:3:0 0,12,115:4:0 +X 938 . C <*> 0 . DP=16;I16=8,7,0,0,553,20669,0,0,846,49010,0,0,231,5001,0,0;QS=3,0;MQSB=0.651439;MQ0F=0 PL:DP:DV 0,24,234:8:0 0,9,77:3:0 0,12,119:4:0 +X 939 . C <*> 0 . DP=16;I16=8,8,0,0,582,22100,0,0,906,52610,0,0,250,5392,0,0;QS=3,0;MQSB=0.702619;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,9,71:3:0 0,12,115:4:0 +X 940 . T <*> 0 . DP=15;I16=8,7,0,0,583,23339,0,0,846,49010,0,0,248,5320,0,0;QS=3,0;MQSB=0.651439;MQ0F=0 PL:DP:DV 0,27,252:9:0 0,6,71:2:0 0,12,124:4:0 +X 941 . G <*> 0 . DP=14;I16=7,7,0,0,501,18707,0,0,786,45410,0,0,246,5216,0,0;QS=3,0;MQSB=0.714506;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,6,59:2:0 0,9,93:3:0 +X 942 . T <*> 0 . DP=14;I16=7,7,0,0,525,19799,0,0,786,45410,0,0,244,5128,0,0;QS=3,0;MQSB=0.714506;MQ0F=0 PL:DP:DV 0,27,237:9:0 0,6,70:2:0 0,9,94:3:0 +X 943 . A <*> 0 . DP=14;I16=7,7,0,0,545,21399,0,0,786,45410,0,0,242,5056,0,0;QS=3,0;MQSB=0.714506;MQ0F=0 PL:DP:DV 0,27,248:9:0 0,6,71:2:0 0,9,93:3:0 +X 944 . G <*> 0 . DP=14;I16=7,7,0,0,529,20143,0,0,786,45410,0,0,240,5000,0,0;QS=3,0;MQSB=0.714506;MQ0F=0 PL:DP:DV 0,27,249:9:0 0,6,65:2:0 0,9,95:3:0 +X 945 . T <*> 0 . DP=14;I16=7,7,0,0,523,19621,0,0,786,45410,0,0,238,4960,0,0;QS=3,0;MQSB=0.714506;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,6,70:2:0 0,9,95:3:0 +X 946 . C <*> 0 . DP=13;I16=6,6,0,0,455,17581,0,0,666,38210,0,0,223,4739,0,0;QS=3,0;MQSB=0.660716;MQ0F=0 PL:DP:DV 0,24,240:8:0 0,6,56:2:0 0,6,70:2:0 +X 947 . C <*> 0 . DP=14;I16=7,7,0,0,509,19007,0,0,755,42651,0,0,238,4928,0,0;QS=3,0;MQSB=0.925999;MQ0F=0 PL:DP:DV 0,27,251:9:0 0,9,83:3:0 0,6,66:2:0 +X 948 . C <*> 0 . DP=14;I16=7,7,0,0,520,20050,0,0,755,42651,0,0,237,4887,0,0;QS=3,0;MQSB=0.925999;MQ0F=0 PL:DP:DV 0,27,254:9:0 0,9,78:3:0 0,6,69:2:0 +X 949 . A <*> 0 . DP=15;I16=7,8,0,0,547,20705,0,0,815,46251,0,0,236,4864,0,0;QS=3,0;MQSB=0.959011;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,9,90:3:0 0,6,72:2:0 +X 950 . G <*> 0 . DP=15;I16=6,8,0,0,563,22871,0,0,786,45410,0,0,231,4835,0,0;QS=3,0;MQSB=0.740818;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,6,71:2:0 0,6,72:2:0 +X 951 . C <*> 0 . DP=16;I16=7,8,0,0,554,21080,0,0,846,49010,0,0,230,4840,0,0;QS=3,0;MQSB=0.720273;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,65:2:0 0,6,73:2:0 +X 952 . T <*> 0 . DP=16;I16=8,8,0,0,595,22565,0,0,875,49851,0,0,237,4913,0,0;QS=3,0;MQSB=0.934676;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,93:3:0 0,6,73:2:0 +X 953 . A <*> 0 . DP=16;I16=8,8,0,0,567,20515,0,0,875,49851,0,0,237,4921,0,0;QS=3,0;MQSB=0.934676;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,91:3:0 0,6,69:2:0 +X 954 . T <*> 0 . DP=15;I16=7,8,0,0,544,20412,0,0,815,46251,0,0,238,4948,0,0;QS=3,0;MQSB=0.959011;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,9,94:3:0 0,6,69:2:0 +X 955 . T <*> 0 . DP=15;I16=7,8,0,0,543,19953,0,0,815,46251,0,0,239,4993,0,0;QS=3,0;MQSB=0.959011;MQ0F=0 PL:DP:DV 0,30,246:10:0 0,9,95:3:0 0,6,68:2:0 +X 956 . C <*> 0 . DP=15;I16=6,8,0,0,543,21255,0,0,786,45410,0,0,229,4935,0,0;QS=3,0;MQSB=0.740818;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,6,62:2:0 0,6,70:2:0 +X 957 . A <*> 0 . DP=15;I16=7,8,0,0,504,17684,0,0,815,46251,0,0,241,5137,0,0;QS=3,0;MQSB=0.959011;MQ0F=0 PL:DP:DV 0,30,240:10:0 0,9,74:3:0 0,6,67:2:0 +X 958 . C <*> 0 . DP=14;I16=6,8,0,0,505,18981,0,0,755,42651,0,0,243,5235,0,0;QS=3,0;MQSB=0.981425;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,9,78:3:0 0,3,39:1:0 +X 959 . A <*> 0 . DP=14;I16=5,8,0,0,519,20885,0,0,726,41810,0,0,231,5153,0,0;QS=3,0;MQSB=0.765017;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,6,72:2:0 0,3,38:1:0 +X 960 . G <*> 0 . DP=15;I16=6,9,0,0,539,19901,0,0,815,46251,0,0,247,5479,0,0;QS=3,0;MQSB=0.99308;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,106:4:0 0,3,41:1:0 +X 961 . T <*> 0 . DP=14;I16=6,8,0,0,523,19835,0,0,755,42651,0,0,250,5574,0,0;QS=3,0;MQSB=0.981425;MQ0F=0 PL:DP:DV 0,27,248:9:0 0,12,114:4:0 0,3,39:1:0 +X 962 . G <*> 0 . DP=14;I16=5,8,0,0,498,19194,0,0,726,41810,0,0,236,5394,0,0;QS=3,0;MQSB=0.765017;MQ0F=0 PL:DP:DV 0,27,253:9:0 0,9,91:3:0 0,3,36:1:0 +X 963 . C <*> 0 . DP=13;I16=5,8,0,0,500,19610,0,0,695,39051,0,0,256,5754,0,0;QS=3,0;MQSB=0.997325;MQ0F=0 PL:DP:DV 0,24,234:8:0 0,12,118:4:0 0,3,40:1:0 +X 964 . T <*> 0 . DP=13;I16=5,8,0,0,512,20430,0,0,695,39051,0,0,259,5835,0,0;QS=3,0;MQSB=0.997325;MQ0F=0 PL:DP:DV 0,24,227:8:0 0,12,128:4:0 0,3,42:1:0 +X 965 . G <*> 0 . DP=13;I16=4,8,0,0,467,18429,0,0,666,38210,0,0,241,5477,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,228:8:0 0,9,93:3:0 0,3,40:1:0 +X 966 . A <*> 0 . DP=13;I16=4,8,0,0,443,16785,0,0,666,38210,0,0,242,5490,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,212:8:0 0,9,95:3:0 0,3,40:1:0 +X 967 . G <*> 0 . DP=13;I16=4,8,0,0,464,18036,0,0,666,38210,0,0,243,5513,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,230:8:0 0,9,91:3:0 0,3,41:1:0 +X 968 . G <*> 0 . DP=13;I16=4,8,0,0,441,16549,0,0,666,38210,0,0,244,5546,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,218:8:0 0,9,87:3:0 0,3,42:1:0 +X 969 . T <*> 0 . DP=13;I16=4,8,0,0,450,16970,0,0,666,38210,0,0,245,5589,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,220:8:0 0,9,98:3:0 0,3,31:1:0 +X 970 . G <*> 0 . DP=13;I16=4,7,0,0,413,15579,0,0,629,36841,0,0,220,4968,0,0;QS=3,0;MQSB=0.924449;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,6,71:2:0 0,3,33:1:0 +X 971 . G <*> 0 . DP=13;I16=4,8,0,0,459,17711,0,0,666,38210,0,0,245,5609,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,223:8:0 0,9,93:3:0 0,3,38:1:0 +X 972 . G <*> 0 . DP=13;I16=4,8,0,0,446,17192,0,0,666,38210,0,0,245,5637,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,210:8:0 0,9,96:3:0 0,3,39:1:0 +X 973 . A <*> 0 . DP=12;I16=4,7,0,0,402,15018,0,0,606,34610,0,0,246,5676,0,0;QS=3,0;MQSB=0.763675;MQ0F=0 PL:DP:DV 0,21,192:7:0 0,9,89:3:0 0,3,42:1:0 +X 974 . A <*> 0 . DP=12;I16=4,7,0,0,417,16273,0,0,606,34610,0,0,247,5725,0,0;QS=3,0;MQSB=0.763675;MQ0F=0 PL:DP:DV 0,21,198:7:0 0,9,96:3:0 0,3,42:1:0 +X 975 . G <*> 0 . DP=13;I16=4,8,0,0,454,17560,0,0,666,38210,0,0,247,5733,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,213:8:0 0,9,95:3:0 0,3,42:1:0 +X 976 . A <*> 0 . DP=13;I16=4,8,0,0,431,16083,0,0,666,38210,0,0,248,5750,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,227:8:0 0,9,70:3:0 0,3,41:1:0 +X 977 . T <*> 0 . DP=13;I16=4,8,0,0,438,16316,0,0,666,38210,0,0,248,5726,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,210:8:0 0,9,93:3:0 0,3,37:1:0 +X 978 . G <*> 0 . DP=12;I16=4,8,0,0,430,16060,0,0,666,38210,0,0,248,5710,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,224:8:0 0,9,75:3:0 0,3,40:1:0 +X 979 . C <*> 0 . DP=13;I16=4,8,0,0,453,17461,0,0,689,40441,0,0,223,5077,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,27,232:9:0 0,6,72:2:0 0,3,41:1:0 +X 980 . T <*> 0 . DP=13;I16=4,8,0,0,438,16412,0,0,689,40441,0,0,224,5078,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,27,220:9:0 0,6,76:2:0 0,3,43:1:0 +X 981 . T <*> 0 . DP=13;I16=4,9,0,0,484,18602,0,0,726,41810,0,0,250,5714,0,0;QS=3,0;MQSB=0.826565;MQ0F=0 PL:DP:DV 0,27,224:9:0 0,9,97:3:0 0,3,41:1:0 +X 982 . G <*> 0 . DP=14;I16=4,10,0,0,520,20128,0,0,786,45410,0,0,250,5686,0,0;QS=3,0;MQSB=0.852144;MQ0F=0 PL:DP:DV 0,30,237:10:0 0,9,99:3:0 0,3,40:1:0 +X 983 . A <*> 0 . DP=14;I16=4,10,0,0,570,23360,0,0,786,45410,0,0,251,5671,0,0;QS=3,0;MQSB=0.852144;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,101:3:0 0,3,42:1:0 +X 984 . G <*> 0 . DP=15;I16=4,10,0,0,529,20459,0,0,786,45410,0,0,252,5670,0,0;QS=3,0;MQSB=0.852144;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,9,88:3:0 0,3,43:1:0 +X 985 . C <*> 0 . DP=17;I16=4,13,0,0,580,20280,0,0,966,56210,0,0,261,5747,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,33,246:11:0 0,12,100:4:0 0,6,65:2:0 +X 986 . C A,<*> 0 . DP=17;I16=3,12,0,1,519,18353,13,169,846,49010,60,3600,235,5101,4,16;QS=2.95873,0.0412698,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.921781;BQB=1;MQ0F=0 PL:DP:DV 0,16,197,27,200,201:10:1 0,12,108,12,108,108:4:0 0,6,69,6,69,69:2:0 +X 987 . C <*> 0 . DP=17;I16=4,13,0,0,634,23914,0,0,966,56210,0,0,267,5755,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,107:4:0 0,6,69:2:0 +X 988 . A <*> 0 . DP=17;I16=4,13,0,0,633,24341,0,0,966,56210,0,0,269,5737,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,111:4:0 0,6,82:2:0 +X 989 . G <*> 0 . DP=17;I16=4,13,0,0,635,24149,0,0,966,56210,0,0,271,5739,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,114:4:0 0,6,80:2:0 +X 990 . G <*> 0 . DP=16;I16=4,12,0,0,591,22177,0,0,906,52610,0,0,274,5760,0,0;QS=3,0;MQSB=0.88901;MQ0F=0 PL:DP:DV 0,30,246:10:0 0,12,105:4:0 0,6,83:2:0 +X 991 . A <*> 0 . DP=16;I16=3,11,0,0,548,21542,0,0,809,47641,0,0,227,4549,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,27,232:9:0 0,9,100:3:0 0,6,80:2:0 +X 992 . G <*> 0 . DP=16;I16=4,12,0,0,562,20436,0,0,906,52610,0,0,278,5760,0,0;QS=3,0;MQSB=0.88901;MQ0F=0 PL:DP:DV 0,30,240:10:0 0,12,102:4:0 0,6,76:2:0 +X 993 . T <*> 0 . DP=16;I16=4,12,0,0,564,20752,0,0,906,52610,0,0,280,5790,0,0;QS=3,0;MQSB=0.88901;MQ0F=0 PL:DP:DV 0,30,222:10:0 0,12,121:4:0 0,6,73:2:0 +X 994 . T <*> 0 . DP=17;I16=5,11,0,0,597,22625,0,0,906,52610,0,0,270,5696,0,0;QS=3,0;MQSB=0.851779;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,12,123:4:0 0,9,103:3:0 +X 995 . C <*> 0 . DP=16;I16=4,11,0,0,588,23228,0,0,846,49010,0,0,273,5741,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,24,216:8:0 0,12,119:4:0 0,9,110:3:0 +X 996 . A <*> 0 . DP=16;I16=4,12,0,0,562,20416,0,0,906,52610,0,0,290,6000,0,0;QS=3,0;MQSB=0.88901;MQ0F=0 PL:DP:DV 0,27,207:9:0 0,12,107:4:0 0,9,113:3:0 +X 997 . A <*> 0 . DP=16;I16=4,12,0,0,600,23520,0,0,906,52610,0,0,294,6110,0,0;QS=3,0;MQSB=0.88901;MQ0F=0 PL:DP:DV 0,27,209:9:0 0,12,123:4:0 0,9,121:3:0 +X 998 . G <*> 0 . DP=17;I16=4,13,0,0,603,22299,0,0,966,56210,0,0,298,6240,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,30,226:10:0 0,12,99:4:0 0,9,115:3:0 +X 999 . G <*> 0 . DP=17;I16=4,12,0,0,575,21519,0,0,906,52610,0,0,302,6390,0,0;QS=3,0;MQSB=0.88901;MQ0F=0 PL:DP:DV 0,27,202:9:0 0,12,118:4:0 0,9,111:3:0 +X 1000 . C <*> 0 . DP=17;I16=4,13,0,0,637,24465,0,0,966,56210,0,0,308,6564,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,30,235:10:0 0,12,118:4:0 0,9,109:3:0 +X 1001 . T <*> 0 . DP=17;I16=4,13,0,0,647,24907,0,0,966,56210,0,0,312,6708,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,30,228:10:0 0,12,120:4:0 0,9,122:3:0 +X 1002 . G <*> 0 . DP=17;I16=4,13,0,0,627,23691,0,0,966,56210,0,0,316,6872,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,30,220:10:0 0,12,123:4:0 0,9,109:3:0 +X 1003 . C T,<*> 0 . DP=18;I16=4,13,0,1,633,23953,22,484,966,56210,60,3600,297,6515,21,441;QS=2.9375,0.0625,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.913725;BQB=1;MQ0F=0 PL:DP:DV 0,8,207,27,211,220:10:1 0,15,132,15,132,132:5:0 0,9,102,9,102,102:3:0 +X 1004 . A <*> 0 . DP=19;I16=5,14,0,0,653,23107,0,0,1086,63410,0,0,321,7061,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,231:11:0 0,15,131:5:0 0,9,98:3:0 +X 1005 . A <*> 0 . DP=19;I16=5,14,0,0,670,24380,0,0,1086,63410,0,0,324,7138,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,231:11:0 0,15,132:5:0 0,9,113:3:0 +X 1006 . T <*> 0 . DP=19;I16=4,14,0,0,659,24869,0,0,1026,59810,0,0,327,7237,0,0;QS=3,0;MQSB=0.913725;MQ0F=0 PL:DP:DV 0,30,220:10:0 0,15,134:5:0 0,9,115:3:0 +X 1007 . G <*> 0 . DP=18;I16=4,13,0,0,651,25373,0,0,966,56210,0,0,306,6732,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,27,225:9:0 0,15,138:5:0 0,9,113:3:0 +X 1008 . A <*> 0 . DP=18;I16=4,13,0,0,667,27041,0,0,966,56210,0,0,309,6821,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,27,222:9:0 0,15,147:5:0 0,9,118:3:0 +X 1009 . G <*> 0 . DP=18;I16=4,13,0,0,635,24431,0,0,966,56210,0,0,312,6928,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,27,213:9:0 0,15,139:5:0 0,9,116:3:0 +X 1010 . C <*> 0 . DP=18;I16=4,14,0,0,661,25289,0,0,1026,59810,0,0,339,7629,0,0;QS=3,0;MQSB=0.913725;MQ0F=0 PL:DP:DV 0,30,234:10:0 0,15,126:5:0 0,9,114:3:0 +X 1011 . T <*> 0 . DP=18;I16=4,14,0,0,671,25325,0,0,1026,59810,0,0,339,7623,0,0;QS=3,0;MQSB=0.913725;MQ0F=0 PL:DP:DV 0,30,226:10:0 0,15,131:5:0 0,9,118:3:0 +X 1012 . A <*> 0 . DP=19;I16=5,14,0,0,639,22891,0,0,1063,61179,0,0,339,7633,0,0;QS=3,0;MQSB=0.990403;MQ0F=0 PL:DP:DV 0,30,201:10:0 0,18,154:6:0 0,9,113:3:0 +X 1013 . T <*> 0 . DP=18;I16=5,12,0,0,623,23913,0,0,943,53979,0,0,325,7385,0,0;QS=3,0;MQSB=0.998612;MQ0F=0 PL:DP:DV 0,24,202:8:0 0,18,161:6:0 0,9,115:3:0 +X 1014 . G <*> 0 . DP=18;I16=5,13,0,0,656,24596,0,0,1003,57579,0,0,341,7605,0,0;QS=3,0;MQSB=0.995153;MQ0F=0 PL:DP:DV 0,27,218:9:0 0,18,159:6:0 0,9,113:3:0 +X 1015 . A <*> 0 . DP=18;I16=5,13,0,0,646,23878,0,0,1003,57579,0,0,342,7618,0,0;QS=3,0;MQSB=0.995153;MQ0F=0 PL:DP:DV 0,27,209:9:0 0,18,164:6:0 0,9,109:3:0 +X 1016 . T <*> 0 . DP=17;I16=4,12,0,0,588,22114,0,0,929,54841,0,0,340,7632,0,0;QS=3,0;MQSB=0.971017;MQ0F=0 PL:DP:DV 0,27,212:9:0 0,12,124:4:0 0,9,101:3:0 +X 1017 . T <*> 0 . DP=18;I16=5,13,0,0,635,23433,0,0,1026,59810,0,0,346,7694,0,0;QS=3,0;MQSB=0.942222;MQ0F=0 PL:DP:DV 0,27,213:9:0 0,18,155:6:0 0,9,105:3:0 +X 1018 . G <*> 0 . DP=18;I16=5,13,0,0,650,24550,0,0,1026,59810,0,0,349,7757,0,0;QS=3,0;MQSB=0.942222;MQ0F=0 PL:DP:DV 0,27,215:9:0 0,18,179:6:0 0,9,91:3:0 +X 1019 . C <*> 0 . DP=18;I16=5,12,0,0,555,18561,0,0,966,56210,0,0,327,7213,0,0;QS=3,0;MQSB=0.951229;MQ0F=0 PL:DP:DV 0,24,181:8:0 0,18,143:6:0 0,9,104:3:0 +X 1020 . G <*> 0 . DP=19;I16=6,12,0,0,625,22287,0,0,1026,59810,0,0,332,7402,0,0;QS=3,0;MQSB=0.97296;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,18,157:6:0 0,9,87:3:0 +X 1021 . C <*> 0 . DP=19;I16=5,13,0,0,625,22761,0,0,1026,59810,0,0,332,7326,0,0;QS=3,0;MQSB=0.942222;MQ0F=0 PL:DP:DV 0,27,220:9:0 0,18,153:6:0 0,9,92:3:0 +X 1022 . C <*> 0 . DP=19;I16=6,13,0,0,727,27975,0,0,1086,63410,0,0,360,8034,0,0;QS=3,0;MQSB=0.965977;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,168:6:0 0,9,110:3:0 +X 1023 . A <*> 0 . DP=19;I16=6,12,0,0,647,23997,0,0,1026,59810,0,0,338,7510,0,0;QS=3,0;MQSB=0.97296;MQ0F=0 PL:DP:DV 0,27,216:9:0 0,18,168:6:0 0,9,112:3:0 +X 1024 . C <*> 0 . DP=20;I16=7,13,0,0,729,27471,0,0,1146,67010,0,0,364,8154,0,0;QS=3,0;MQSB=0.980568;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,169:6:0 0,9,106:3:0 +X 1025 . T <*> 0 . DP=20;I16=7,13,0,0,757,29387,0,0,1146,67010,0,0,366,8192,0,0;QS=3,0;MQSB=0.980568;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,181:6:0 0,9,117:3:0 +X 1026 . G <*> 0 . DP=20;I16=7,13,0,0,747,28435,0,0,1146,67010,0,0,367,8201,0,0;QS=3,0;MQSB=0.980568;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,169:6:0 0,9,113:3:0 +X 1027 . C <*> 0 . DP=20;I16=7,13,0,0,720,26688,0,0,1146,67010,0,0,368,8232,0,0;QS=3,0;MQSB=0.980568;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,145:6:0 0,9,110:3:0 +X 1028 . A <*> 0 . DP=19;I16=6,12,0,0,645,23681,0,0,1026,59810,0,0,348,7800,0,0;QS=3,0;MQSB=0.97296;MQ0F=0 PL:DP:DV 0,30,238:10:0 0,15,146:5:0 0,9,99:3:0 +X 1029 . C <*> 0 . DP=19;I16=7,12,0,0,699,26817,0,0,1086,63410,0,0,371,8305,0,0;QS=3,0;MQSB=0.985816;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,138:5:0 0,9,111:3:0 +X 1030 . T <*> 0 . DP=19;I16=7,12,0,0,749,29789,0,0,1086,63410,0,0,371,8293,0,0;QS=3,0;MQSB=0.985816;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,158:5:0 0,9,122:3:0 +X 1031 . T <*> 0 . DP=21;I16=9,12,0,0,748,27726,0,0,1206,70610,0,0,371,8297,0,0;QS=3,0;MQSB=0.997478;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,144:5:0 0,9,113:3:0 +X 1032 . T <*> 0 . DP=21;I16=9,12,0,0,761,28033,0,0,1206,70610,0,0,373,8319,0,0;QS=3,0;MQSB=0.997478;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,156:5:0 0,9,111:3:0 +X 1033 . G <*> 0 . DP=22;I16=10,12,0,0,773,28227,0,0,1266,74210,0,0,375,8361,0,0;QS=3,0;MQSB=0.999457;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,169:6:0 0,9,101:3:0 +X 1034 . G <*> 0 . DP=22;I16=8,12,0,0,703,25617,0,0,1169,69241,0,0,340,7684,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,149:5:0 0,9,102:3:0 +X 1035 . C <*> 0 . DP=21;I16=10,11,0,0,719,26103,0,0,1237,73369,0,0,382,8508,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,163:6:0 0,9,94:3:0 +X 1036 . C <*> 0 . DP=22;I16=11,10,0,0,756,28390,0,0,1237,73369,0,0,360,7938,0,0;QS=3,0;MQSB=0.939898;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,175:6:0 0,12,135:4:0 +X 1037 . T <*> 0 . DP=22;I16=11,11,0,0,839,32737,0,0,1297,76969,0,0,389,8641,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,188:6:0 0,12,138:4:0 +X 1038 . G <*> 0 . DP=21;I16=10,10,0,0,752,28750,0,0,1177,69769,0,0,368,8066,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,184:6:0 0,9,107:3:0 +X 1039 . G <*> 0 . DP=21;I16=10,11,0,0,775,29373,0,0,1237,73369,0,0,397,8761,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,189:6:0 0,9,111:3:0 +X 1040 . A <*> 0 . DP=21;I16=10,11,0,0,759,28007,0,0,1237,73369,0,0,401,8851,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,177:6:0 0,9,107:3:0 +X 1041 . C <*> 0 . DP=21;I16=8,11,0,0,713,27117,0,0,1140,68400,0,0,371,8255,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,155:5:0 0,9,110:3:0 +X 1042 . A <*> 0 . DP=23;I16=12,10,0,0,800,29464,0,0,1297,76969,0,0,384,8466,0,0;QS=3,0;MQSB=0.947103;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,185:6:0 0,15,145:5:0 +X 1043 . A <*> 0 . DP=23;I16=12,11,0,0,850,32160,0,0,1357,80569,0,0,414,9192,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,188:6:0 0,15,159:5:0 +X 1044 . C <*> 0 . DP=23;I16=12,10,0,0,812,30758,0,0,1297,76969,0,0,394,8690,0,0;QS=3,0;MQSB=0.947103;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,181:6:0 0,15,150:5:0 +X 1045 . A <*> 0 . DP=23;I16=12,11,0,0,887,34519,0,0,1357,80569,0,0,424,9460,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,197:6:0 0,15,156:5:0 +X 1046 . G <*> 0 . DP=23;I16=12,11,0,0,862,33240,0,0,1357,80569,0,0,428,9576,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,183:6:0 0,15,158:5:0 +X 1047 . A <*> 0 . DP=23;I16=12,11,0,0,890,34804,0,0,1357,80569,0,0,432,9712,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,198:6:0 0,15,165:5:0 +X 1048 . G <*> 0 . DP=23;I16=12,10,0,0,846,33054,0,0,1297,76969,0,0,411,9243,0,0;QS=3,0;MQSB=0.947103;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,195:6:0 0,15,156:5:0 +X 1049 . C <*> 0 . DP=22;I16=12,10,0,0,808,30644,0,0,1297,76969,0,0,441,10043,0,0;QS=3,0;MQSB=0.947103;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,182:6:0 0,15,160:5:0 +X 1050 . A <*> 0 . DP=22;I16=11,10,0,0,808,31334,0,0,1237,73369,0,0,430,9940,0,0;QS=3,0;MQSB=0.939898;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,193:6:0 0,12,138:4:0 +X 1051 . A <*> 0 . DP=21;I16=11,9,0,0,731,27495,0,0,1177,69769,0,0,423,9621,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,18,187:6:0 0,15,150:5:0 +X 1052 . A <*> 0 . DP=21;I16=11,9,0,0,759,29327,0,0,1177,69769,0,0,427,9747,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,27,247:9:0 0,18,190:6:0 0,15,150:5:0 +X 1053 . A <*> 0 . DP=21;I16=11,8,0,0,674,25210,0,0,1117,66169,0,0,406,9264,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,24,224:8:0 0,18,161:6:0 0,15,149:5:0 +X 1054 . C <*> 0 . DP=21;I16=11,10,0,0,791,30157,0,0,1237,73369,0,0,459,10623,0,0;QS=3,0;MQSB=0.939898;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,189:6:0 0,15,153:5:0 +X 1055 . C <*> 0 . DP=22;I16=12,10,0,0,818,31448,0,0,1297,76969,0,0,462,10750,0,0;QS=3,0;MQSB=0.947103;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,191:6:0 0,15,157:5:0 +X 1056 . C <*> 0 . DP=22;I16=12,9,0,0,793,31265,0,0,1237,73369,0,0,441,10271,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,195:6:0 0,15,161:5:0 +X 1057 . T <*> 0 . DP=23;I16=12,10,0,0,821,31667,0,0,1297,76969,0,0,467,10911,0,0;QS=3,0;MQSB=0.947103;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,196:6:0 0,15,159:5:0 +X 1058 . G <*> 0 . DP=23;I16=12,11,0,0,863,32871,0,0,1357,80569,0,0,493,11569,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,197:7:0 0,15,155:5:0 +X 1059 . T <*> 0 . DP=23;I16=12,10,0,0,797,29803,0,0,1297,76969,0,0,468,10944,0,0;QS=3,0;MQSB=0.947103;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,21,202:7:0 0,15,152:5:0 +X 1060 . C <*> 0 . DP=23;I16=12,11,0,0,829,31041,0,0,1357,80569,0,0,492,11536,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,178:7:0 0,15,163:5:0 +X 1061 . T <*> 0 . DP=22;I16=12,9,0,0,810,31840,0,0,1237,73369,0,0,465,10797,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,175:5:0 0,15,158:5:0 +X 1062 . C A,<*> 0 . DP=22;I16=12,9,0,1,826,32780,33,1089,1237,73369,60,3600,462,10652,25,625;QS=2.85398,0.146018,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.947103;BQB=1;MQ0F=0 PL:DP:DV 0,33,255,33,255,255:11:0 15,0,151,30,154,176:6:1 0,15,164,15,164,164:5:0 +X 1063 . T <*> 0 . DP=22;I16=12,9,0,0,820,32460,0,0,1237,73369,0,0,459,10525,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,183:6:0 0,15,166:5:0 +X 1064 . A <*> 0 . DP=23;I16=12,9,0,0,793,30355,0,0,1237,73369,0,0,464,10752,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,180:6:0 0,15,162:5:0 +X 1065 . A <*> 0 . DP=23;I16=12,9,0,0,814,31978,0,0,1237,73369,0,0,462,10694,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,186:6:0 0,15,174:5:0 +X 1066 . A <*> 0 . DP=27;I16=15,9,0,0,890,34378,0,0,1417,84169,0,0,460,10652,0,0;QS=3,0;MQSB=0.96464;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,198:7:0 0,18,181:6:0 +X 1067 . A <*> 0 . DP=27;I16=15,10,0,0,913,35031,0,0,1477,87769,0,0,470,10600,0,0;QS=3,0;MQSB=0.962269;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,208:7:0 0,18,182:6:0 +X 1068 . A <*> 0 . DP=27;I16=15,9,0,0,898,34580,0,0,1417,84169,0,0,456,10342,0,0;QS=3,0;MQSB=0.96464;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,24,218:8:0 0,18,181:6:0 +X 1069 . A <*> 0 . DP=28;I16=16,10,0,0,914,33888,0,0,1537,91369,0,0,481,10925,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,207:8:0 0,21,177:7:0 +X 1070 . A <*> 0 . DP=28;I16=15,11,0,0,955,36445,0,0,1537,91369,0,0,467,10351,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,223:8:0 0,21,188:7:0 +X 1071 . G <*> 0 . DP=28;I16=16,10,0,0,974,37570,0,0,1537,91369,0,0,466,10284,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,192:7:0 0,21,191:7:0 +X 1072 . A <*> 0 . DP=28;I16=16,11,0,0,1007,38205,0,0,1597,94969,0,0,490,10868,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,239:8:0 0,21,195:7:0 +X 1073 . A <*> 0 . DP=28;I16=16,10,0,0,976,37822,0,0,1537,91369,0,0,463,10177,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,24,236:8:0 0,21,199:7:0 +X 1074 . A <*> 0 . DP=28;I16=16,11,0,0,1003,38097,0,0,1597,94969,0,0,484,10664,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,232:8:0 0,21,203:7:0 +X 1075 . A <*> 0 . DP=28;I16=16,10,0,0,964,36762,0,0,1537,91369,0,0,476,10564,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,222:8:0 0,21,200:7:0 +X 1076 . G <*> 0 . DP=28;I16=16,10,0,0,966,37048,0,0,1537,91369,0,0,476,10536,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,209:8:0 0,21,183:7:0 +X 1077 . A <*> 0 . DP=29;I16=17,11,0,0,1038,39240,0,0,1657,98569,0,0,480,10548,0,0;QS=3,0;MQSB=0.967085;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,231:8:0 0,24,209:8:0 +X 1078 . A <*> 0 . DP=29;I16=17,11,0,0,1053,40425,0,0,1657,98569,0,0,480,10562,0,0;QS=3,0;MQSB=0.967085;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,234:8:0 0,24,214:8:0 +X 1079 . A <*> 0 . DP=28;I16=17,10,0,0,1019,39007,0,0,1597,94969,0,0,479,10505,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,223:8:0 0,24,206:8:0 +X 1080 . A <*> 0 . DP=29;I16=18,10,0,0,1049,40827,0,0,1657,98569,0,0,478,10478,0,0;QS=3,0;MQSB=0.971673;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,246:9:0 0,24,218:8:0 +X 1081 . G <*> 0 . DP=30;I16=19,8,0,0,988,37392,0,0,1597,94969,0,0,436,9550,0,0;QS=3,0;MQSB=0.977696;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,210:8:0 0,27,210:9:0 +X 1082 . A <*> 0 . DP=30;I16=20,7,0,0,989,37109,0,0,1597,94969,0,0,438,9564,0,0;QS=3,0;MQSB=0.981425;MQ0F=0 PL:DP:DV 0,27,224:9:0 0,27,226:9:0 0,27,217:9:0 +X 1083 . A <*> 0 . DP=30;I16=20,8,0,0,1039,39827,0,0,1657,98569,0,0,455,9803,0,0;QS=3,0;MQSB=0.979523;MQ0F=0 PL:DP:DV 0,30,246:10:0 0,27,233:9:0 0,27,217:9:0 +X 1084 . A <*> 0 . DP=31;I16=21,8,0,0,1049,39097,0,0,1717,102169,0,0,457,9849,0,0;QS=3,0;MQSB=0.981133;MQ0F=0 PL:DP:DV 0,33,253:11:0 0,27,226:9:0 0,27,215:9:0 +X 1085 . A <*> 0 . DP=30;I16=21,8,0,0,1052,39534,0,0,1717,102169,0,0,486,10552,0,0;QS=3,0;MQSB=0.981133;MQ0F=0 PL:DP:DV 0,30,232:10:0 0,30,247:10:0 0,27,214:9:0 +X 1086 . A <*> 0 . DP=28;I16=21,6,0,0,969,36223,0,0,1597,94969,0,0,492,10660,0,0;QS=3,0;MQSB=0.98481;MQ0F=0 PL:DP:DV 0,30,219:10:0 0,27,236:9:0 0,24,179:8:0 +X 1087 . C <*> 0 . DP=28;I16=22,6,0,0,984,36046,0,0,1657,98569,0,0,498,10796,0,0;QS=3,0;MQSB=0.985992;MQ0F=0 PL:DP:DV 0,30,234:10:0 0,27,229:9:0 0,27,173:9:0 +X 1088 . T <*> 0 . DP=29;I16=23,6,0,0,1133,45203,0,0,1717,102169,0,0,503,10863,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,30,250:10:0 0,27,198:9:0 +X 1089 . C <*> 0 . DP=29;I16=23,6,0,0,1093,42347,0,0,1717,102169,0,0,509,10965,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,30,237:10:0 0,27,188:9:0 +X 1090 . A <*> 0 . DP=29;I16=23,6,0,0,1061,39845,0,0,1717,102169,0,0,515,11103,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,221:10:0 0,30,250:10:0 0,27,183:9:0 +X 1091 . C <*> 0 . DP=29;I16=23,6,0,0,1063,39713,0,0,1717,102169,0,0,521,11277,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,30,244:10:0 0,27,177:9:0 +X 1092 . T <*> 0 . DP=29;I16=23,6,0,0,1121,44489,0,0,1717,102169,0,0,524,11334,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,244:10:0 0,30,251:10:0 0,27,198:9:0 +X 1093 . G <*> 0 . DP=29;I16=23,6,0,0,1085,41377,0,0,1717,102169,0,0,526,11372,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,30,243:10:0 0,27,184:9:0 +X 1094 . G <*> 0 . DP=29;I16=22,6,0,0,1018,38808,0,0,1657,98569,0,0,521,11393,0,0;QS=3,0;MQSB=0.985992;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,30,232:10:0 0,24,185:8:0 +X 1095 . A <*> 0 . DP=28;I16=22,6,0,0,1023,38551,0,0,1657,98569,0,0,529,11443,0,0;QS=3,0;MQSB=0.985992;MQ0F=0 PL:DP:DV 0,30,236:10:0 0,30,244:10:0 0,24,178:8:0 +X 1096 . T <*> 0 . DP=30;I16=24,5,0,0,1020,37168,0,0,1717,102169,0,0,505,10849,0,0;QS=3,0;MQSB=0.989637;MQ0F=0 PL:DP:DV 0,33,234:11:0 0,27,220:9:0 0,27,178:9:0 +X 1097 . A <*> 0 . DP=30;I16=24,6,0,0,1056,38166,0,0,1777,105769,0,0,533,11537,0,0;QS=3,0;MQSB=0.987976;MQ0F=0 PL:DP:DV 0,33,230:11:0 0,30,237:10:0 0,27,177:9:0 +X 1098 . T <*> 0 . DP=29;I16=24,5,0,0,1081,40557,0,0,1717,102169,0,0,537,11633,0,0;QS=3,0;MQSB=0.989637;MQ0F=0 PL:DP:DV 0,30,210:10:0 0,30,251:10:0 0,27,186:9:0 +X 1099 . G <*> 0 . DP=29;I16=24,5,0,0,1091,41719,0,0,1717,102169,0,0,540,11712,0,0;QS=3,0;MQSB=0.989637;MQ0F=0 PL:DP:DV 0,30,229:10:0 0,30,242:10:0 0,27,182:9:0 +X 1100 . A <*> 0 . DP=29;I16=24,5,0,0,1106,42976,0,0,1717,102169,0,0,543,11825,0,0;QS=3,0;MQSB=0.989637;MQ0F=0 PL:DP:DV 0,30,210:10:0 0,30,255:10:0 0,27,191:9:0 +X 1101 . A <*> 0 . DP=29;I16=24,5,0,0,1154,46420,0,0,1717,102169,0,0,545,11921,0,0;QS=3,0;MQSB=0.989637;MQ0F=0 PL:DP:DV 0,30,222:10:0 0,30,255:10:0 0,27,198:9:0 +X 1102 . T <*> 0 . DP=29;I16=24,4,0,0,1046,39520,0,0,1657,98569,0,0,522,11424,0,0;QS=3,0;MQSB=0.991416;MQ0F=0 PL:DP:DV 0,30,210:10:0 0,27,233:9:0 0,27,186:9:0 +X 1103 . G <*> 0 . DP=30;I16=24,6,0,0,1134,43486,0,0,1777,105769,0,0,548,12158,0,0;QS=3,0;MQSB=0.987976;MQ0F=0 PL:DP:DV 0,30,223:10:0 0,30,255:10:0 0,30,222:10:0 +X 1104 . A <*> 0 . DP=28;I16=23,5,0,0,1089,43067,0,0,1657,98569,0,0,552,12296,0,0;QS=3,0;MQSB=0.988819;MQ0F=0 PL:DP:DV 0,27,213:9:0 0,27,233:9:0 0,30,233:10:0 +X 1105 . T <*> 0 . DP=28;I16=23,5,0,0,1035,38743,0,0,1657,98569,0,0,556,12462,0,0;QS=3,0;MQSB=0.988819;MQ0F=0 PL:DP:DV 0,27,203:9:0 0,27,227:9:0 0,30,222:10:0 +X 1106 . A <*> 0 . DP=29;I16=23,5,0,0,1003,36715,0,0,1657,98569,0,0,532,11882,0,0;QS=3,0;MQSB=0.988819;MQ0F=0 PL:DP:DV 0,30,227:10:0 0,24,198:8:0 0,30,217:10:0 +X 1107 . C <*> 0 . DP=29;I16=23,6,0,0,1093,41509,0,0,1717,102169,0,0,558,12532,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,244:10:0 0,27,233:9:0 0,30,220:10:0 +X 1108 . A <*> 0 . DP=29;I16=23,6,0,0,1138,44908,0,0,1717,102169,0,0,558,12536,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,239:10:0 0,27,253:9:0 0,30,227:10:0 +X 1109 . G <*> 0 . DP=29;I16=23,6,0,0,1140,45200,0,0,1717,102169,0,0,557,12519,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,27,240:9:0 0,30,224:10:0 +X 1110 . G <*> 0 . DP=29;I16=23,6,0,0,1086,41054,0,0,1717,102169,0,0,555,12481,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,242:10:0 0,27,229:9:0 0,30,224:10:0 +X 1111 . T <*> 0 . DP=29;I16=22,6,0,0,1025,37919,0,0,1680,100800,0,0,552,12470,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,227:10:0 0,24,227:8:0 0,30,211:10:0 +X 1112 . T <*> 0 . DP=28;I16=22,6,0,0,1034,38986,0,0,1680,100800,0,0,550,12440,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,226:10:0 0,24,221:8:0 0,30,221:10:0 +X 1113 . G <*> 0 . DP=28;I16=23,5,0,0,1085,42273,0,0,1680,100800,0,0,548,12386,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,202:7:0 0,33,222:11:0 +X 1114 . A <*> 0 . DP=28;I16=23,5,0,0,1079,42279,0,0,1680,100800,0,0,546,12306,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,235:10:0 0,21,209:7:0 0,33,238:11:0 +X 1115 . G <*> 0 . DP=28;I16=23,5,0,0,1114,44550,0,0,1680,100800,0,0,544,12250,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,208:7:0 0,33,234:11:0 +X 1116 . G <*> 0 . DP=29;I16=24,5,0,0,1059,39531,0,0,1740,104400,0,0,542,12218,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,236:10:0 0,24,204:8:0 0,33,226:11:0 +X 1117 . A <*> 0 . DP=29;I16=24,5,0,0,1124,43896,0,0,1740,104400,0,0,541,12211,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,235:10:0 0,24,227:8:0 0,33,234:11:0 +X 1118 . T <*> 0 . DP=29;I16=24,4,0,0,1100,44802,0,0,1680,100800,0,0,539,12131,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,230:10:0 0,21,188:7:0 0,33,248:11:0 +X 1119 . C <*> 0 . DP=29;I16=23,4,0,0,1078,44864,0,0,1620,97200,0,0,526,11958,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,224:9:0 0,21,191:7:0 0,33,255:11:0 +X 1120 . C <*> 0 . DP=29;I16=23,5,0,0,1113,46071,0,0,1680,100800,0,0,536,12054,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,24,214:8:0 0,33,255:11:0 +X 1121 . A <*> 0 . DP=30;I16=24,5,0,0,1167,48549,0,0,1740,104400,0,0,536,12056,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,24,220:8:0 0,36,255:12:0 +X 1122 . T <*> 0 . DP=32;I16=26,5,0,0,1235,50967,0,0,1860,111600,0,0,535,11985,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,230:10:0 0,27,238:9:0 0,36,255:12:0 +X 1123 . T <*> 0 . DP=32;I16=26,5,0,0,1219,50121,0,0,1860,111600,0,0,535,11893,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,221:10:0 0,27,236:9:0 0,36,255:12:0 +X 1124 . A <*> 0 . DP=31;I16=25,5,0,0,1187,48827,0,0,1800,108000,0,0,536,11832,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,218:9:0 0,27,235:9:0 0,36,255:12:0 +X 1125 . T <*> 0 . DP=31;I16=25,5,0,0,1211,51001,0,0,1800,108000,0,0,537,11801,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,27,235:9:0 0,36,255:12:0 +X 1126 . C <*> 0 . DP=31;I16=25,5,0,0,1225,52001,0,0,1800,108000,0,0,538,11800,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,234:9:0 0,27,241:9:0 0,36,255:12:0 +X 1127 . T <*> 0 . DP=31;I16=25,5,0,0,1257,55245,0,0,1800,108000,0,0,539,11829,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,231:9:0 0,27,252:9:0 0,36,255:12:0 +X 1128 . G <*> 0 . DP=31;I16=25,5,0,0,1217,51743,0,0,1800,108000,0,0,540,11888,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,236:9:0 0,27,229:9:0 0,36,255:12:0 +X 1129 . A G,<*> 0 . DP=31;I16=24,4,0,1,1101,45631,32,1024,1680,100800,60,3600,514,11300,25,625;QS=2.93535,0.0646465,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,24,204,24,204,204:8:0 0,27,229,27,229,229:9:0 0,4,198,33,201,219:12:1 +X 1130 . A <*> 0 . DP=31;I16=25,5,0,0,1189,49509,0,0,1800,108000,0,0,539,11943,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,215:9:0 0,27,236:9:0 0,36,255:12:0 +X 1131 . A <*> 0 . DP=29;I16=23,5,0,0,1156,49362,0,0,1680,100800,0,0,540,11988,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,206:7:0 0,27,250:9:0 0,36,255:12:0 +X 1132 . T <*> 0 . DP=29;I16=23,5,0,0,1123,47359,0,0,1680,100800,0,0,540,12008,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,198:7:0 0,27,229:9:0 0,36,255:12:0 +X 1133 . G <*> 0 . DP=30;I16=23,5,0,0,1148,48796,0,0,1680,100800,0,0,540,12052,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,214:7:0 0,27,232:9:0 0,36,255:12:0 +X 1134 . C <*> 0 . DP=29;I16=22,6,0,0,1162,50224,0,0,1680,100800,0,0,547,12155,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,209:7:0 0,27,254:9:0 0,36,255:12:0 +X 1135 . T <*> 0 . DP=29;I16=22,6,0,0,1214,55020,0,0,1680,100800,0,0,549,12257,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,209:7:0 0,27,255:9:0 0,36,255:12:0 +X 1136 . T <*> 0 . DP=29;I16=22,6,0,0,1148,49270,0,0,1680,100800,0,0,551,12383,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,200:7:0 0,27,255:9:0 0,36,255:12:0 +X 1137 . G <*> 0 . DP=28;I16=21,6,0,0,1087,46051,0,0,1620,97200,0,0,554,12532,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,214:7:0 0,27,234:9:0 0,33,254:11:0 +X 1138 . G <*> 0 . DP=28;I16=21,6,0,0,1040,42504,0,0,1620,97200,0,0,557,12703,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,197:7:0 0,27,234:9:0 0,33,246:11:0 +X 1139 . A <*> 0 . DP=28;I16=21,6,0,0,1103,47389,0,0,1620,97200,0,0,559,12845,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,200:7:0 0,27,254:9:0 0,33,255:11:0 +X 1140 . C <*> 0 . DP=28;I16=21,6,0,0,1072,44372,0,0,1620,97200,0,0,561,13007,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,214:7:0 0,27,234:9:0 0,33,250:11:0 +X 1141 . C <*> 0 . DP=28;I16=21,6,0,0,1106,47298,0,0,1620,97200,0,0,562,13140,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,212:7:0 0,27,245:9:0 0,33,255:11:0 +X 1142 . A <*> 0 . DP=28;I16=21,6,0,0,1114,47788,0,0,1620,97200,0,0,560,13146,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,212:7:0 0,27,255:9:0 0,33,251:11:0 +X 1143 . G <*> 0 . DP=26;I16=19,7,0,0,1041,42249,0,0,1560,93600,0,0,585,13799,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,222:7:0 0,27,249:9:0 0,30,253:10:0 +X 1144 . A <*> 0 . DP=26;I16=19,7,0,0,1018,40154,0,0,1560,93600,0,0,585,13847,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,205:7:0 0,27,250:9:0 0,30,255:10:0 +X 1145 . T <*> 0 . DP=26;I16=19,7,0,0,1016,39852,0,0,1560,93600,0,0,584,13866,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,206:7:0 0,27,250:9:0 0,30,249:10:0 +X 1146 . G <*> 0 . DP=26;I16=19,7,0,0,1011,39743,0,0,1560,93600,0,0,582,13856,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,210:7:0 0,27,246:9:0 0,30,254:10:0 +X 1147 . T <*> 0 . DP=27;I16=20,6,0,0,1010,39730,0,0,1560,93600,0,0,579,13815,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,207:8:0 0,24,234:8:0 0,30,255:10:0 +X 1148 . T <*> 0 . DP=26;I16=20,6,0,0,1002,39214,0,0,1560,93600,0,0,576,13690,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,196:8:0 0,24,237:8:0 0,30,255:10:0 +X 1149 . T <*> 0 . DP=26;I16=20,6,0,0,1022,40532,0,0,1560,93600,0,0,573,13579,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,205:8:0 0,24,231:8:0 0,30,255:10:0 +X 1150 . T <*> 0 . DP=26;I16=20,6,0,0,1032,41212,0,0,1560,93600,0,0,569,13433,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,208:8:0 0,24,236:8:0 0,30,255:10:0 +X 1151 . G <*> 0 . DP=26;I16=20,6,0,0,1021,40285,0,0,1560,93600,0,0,565,13303,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,220:8:0 0,24,231:8:0 0,30,248:10:0 +X 1152 . A <*> 0 . DP=27;I16=20,7,0,0,1040,40772,0,0,1620,97200,0,0,561,13189,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,202:8:0 0,24,230:8:0 0,33,255:11:0 +X 1153 . A <*> 0 . DP=27;I16=20,7,0,0,1039,40717,0,0,1620,97200,0,0,557,13043,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,202:8:0 0,24,233:8:0 0,33,255:11:0 +X 1154 . T <*> 0 . DP=28;I16=21,7,0,0,1073,41861,0,0,1680,100800,0,0,552,12866,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,212:9:0 0,24,236:8:0 0,33,255:11:0 +X 1155 . T <*> 0 . DP=27;I16=20,7,0,0,1074,43046,0,0,1620,97200,0,0,549,12707,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,211:8:0 0,24,236:8:0 0,33,255:11:0 +X 1156 . T <*> 0 . DP=28;I16=19,8,0,0,1065,42533,0,0,1620,97200,0,0,520,11892,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,210:8:0 0,24,239:8:0 0,33,255:11:0 +X 1157 . T <*> 0 . DP=28;I16=20,8,0,0,1094,43108,0,0,1680,100800,0,0,541,12299,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,230:9:0 0,24,230:8:0 0,33,255:11:0 +X 1158 . G <*> 0 . DP=28;I16=20,8,0,0,1098,43584,0,0,1680,100800,0,0,536,12056,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,24,224:8:0 0,33,255:11:0 +X 1159 . G <*> 0 . DP=28;I16=20,8,0,0,1096,43222,0,0,1680,100800,0,0,530,11790,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,249:9:0 0,24,229:8:0 0,33,255:11:0 +X 1160 . A <*> 0 . DP=30;I16=20,10,0,0,1146,44510,0,0,1800,108000,0,0,524,11552,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,229:9:0 0,24,242:8:0 0,39,255:13:0 +X 1161 . T <*> 0 . DP=30;I16=20,10,0,0,1136,43548,0,0,1800,108000,0,0,520,11344,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,221:9:0 0,24,230:8:0 0,39,255:13:0 +X 1162 . T <*> 0 . DP=30;I16=20,10,0,0,1147,44365,0,0,1800,108000,0,0,516,11168,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,232:9:0 0,24,229:8:0 0,39,255:13:0 +X 1163 . T <*> 0 . DP=31;I16=20,11,0,0,1176,45394,0,0,1860,111600,0,0,511,10975,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,24,231:8:0 0,39,255:13:0 +X 1164 . T <*> 0 . DP=31;I16=20,11,0,0,1166,44864,0,0,1860,111600,0,0,506,10768,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,235:10:0 0,24,234:8:0 0,39,255:13:0 +X 1165 . T <*> 0 . DP=31;I16=20,11,0,0,1189,46635,0,0,1860,111600,0,0,501,10599,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,240:10:0 0,24,231:8:0 0,39,255:13:0 +X 1166 . T <*> 0 . DP=30;I16=19,11,0,0,1137,43791,0,0,1800,108000,0,0,497,10467,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,231:9:0 0,24,228:8:0 0,39,255:13:0 +X 1167 . C <*> 0 . DP=28;I16=17,11,0,0,1114,44588,0,0,1680,100800,0,0,495,10369,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,21,216:7:0 0,36,255:12:0 +X 1168 . A <*> 0 . DP=28;I16=17,11,0,0,1074,41862,0,0,1680,100800,0,0,493,10303,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,21,203:7:0 0,36,255:12:0 +X 1169 . T <*> 0 . DP=28;I16=17,11,0,0,1089,42589,0,0,1680,100800,0,0,491,10269,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,247:9:0 0,21,212:7:0 0,36,255:12:0 +X 1170 . A <*> 0 . DP=27;I16=16,11,0,0,1033,39891,0,0,1620,97200,0,0,490,10266,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,21,214:7:0 0,33,255:11:0 +X 1171 . T <*> 0 . DP=28;I16=17,11,0,0,1086,42472,0,0,1680,100800,0,0,488,10244,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,249:9:0 0,24,223:8:0 0,33,255:11:0 +X 1172 . T <*> 0 . DP=28;I16=17,11,0,0,1086,42598,0,0,1680,100800,0,0,486,10206,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,235:9:0 0,24,228:8:0 0,33,255:11:0 +X 1173 . T <*> 0 . DP=29;I16=18,11,0,0,1126,44348,0,0,1740,104400,0,0,483,10153,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,27,241:9:0 0,33,255:11:0 +X 1174 . T <*> 0 . DP=29;I16=18,11,0,0,1098,42352,0,0,1740,104400,0,0,481,10135,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,230:9:0 0,27,238:9:0 0,33,255:11:0 +X 1175 . G <*> 0 . DP=28;I16=18,10,0,0,1063,40975,0,0,1680,100800,0,0,480,10152,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,234:8:0 0,27,234:9:0 0,33,255:11:0 +X 1176 . T <*> 0 . DP=28;I16=18,10,0,0,1045,39823,0,0,1680,100800,0,0,479,10203,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,27,233:9:0 0,33,255:11:0 +X 1177 . A <*> 0 . DP=28;I16=18,10,0,0,1040,39006,0,0,1680,100800,0,0,478,10288,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,220:8:0 0,27,228:9:0 0,33,255:11:0 +X 1178 . A <*> 0 . DP=27;I16=17,10,0,0,1006,38238,0,0,1620,97200,0,0,477,10355,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,27,227:9:0 0,30,255:10:0 +X 1179 . T <*> 0 . DP=27;I16=17,10,0,0,1012,38396,0,0,1620,97200,0,0,475,10403,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,223:8:0 0,27,224:9:0 0,30,255:10:0 +X 1180 . C <*> 0 . DP=27;I16=16,10,0,0,1006,39508,0,0,1560,93600,0,0,469,10423,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,222:7:0 0,27,224:9:0 0,30,255:10:0 +X 1181 . T <*> 0 . DP=26;I16=16,10,0,0,1021,40581,0,0,1560,93600,0,0,469,10441,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,236:8:0 0,24,229:8:0 0,30,255:10:0 +X 1182 . T <*> 0 . DP=26;I16=14,11,0,0,939,35915,0,0,1500,90000,0,0,457,10347,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,236:9:0 0,21,209:7:0 0,27,255:9:0 +X 1183 . T <*> 0 . DP=25;I16=13,11,0,0,899,34555,0,0,1440,86400,0,0,455,10341,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,18,192:6:0 0,27,255:9:0 +X 1184 . G <*> 0 . DP=24;I16=13,11,0,0,916,35398,0,0,1440,86400,0,0,465,10479,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,234:8:0 0,21,201:7:0 0,27,255:9:0 +X 1185 . C <*> 0 . DP=24;I16=13,11,0,0,908,35014,0,0,1440,86400,0,0,465,10541,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,246:8:0 0,21,191:7:0 0,27,250:9:0 +X 1186 . A <*> 0 . DP=24;I16=13,11,0,0,946,37648,0,0,1440,86400,0,0,463,10525,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,240:8:0 0,21,205:7:0 0,27,255:9:0 +X 1187 . G <*> 0 . DP=25;I16=14,11,0,0,908,33870,0,0,1500,90000,0,0,461,10529,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,21,205:7:0 0,27,240:9:0 +X 1188 . T <*> 0 . DP=25;I16=14,11,0,0,886,32138,0,0,1500,90000,0,0,461,10553,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,21,196:7:0 0,24,216:8:0 +X 1189 . A <*> 0 . DP=25;I16=14,11,0,0,920,34392,0,0,1500,90000,0,0,461,10497,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,174:6:0 0,27,252:9:0 +X 1190 . T <*> 0 . DP=26;I16=14,12,0,0,960,35876,0,0,1560,93600,0,0,462,10462,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,185:6:0 0,27,252:9:0 +X 1191 . A <*> 0 . DP=26;I16=14,12,0,0,928,33922,0,0,1560,93600,0,0,464,10450,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,173:6:0 0,27,245:9:0 +X 1192 . T <*> 0 . DP=26;I16=14,12,0,0,981,37505,0,0,1560,93600,0,0,465,10413,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,191:6:0 0,27,255:9:0 +X 1193 . T <*> 0 . DP=26;I16=14,12,0,0,976,37054,0,0,1560,93600,0,0,466,10402,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,191:6:0 0,27,255:9:0 +X 1194 . T <*> 0 . DP=26;I16=14,12,0,0,951,35219,0,0,1560,93600,0,0,466,10368,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,178:6:0 0,27,249:9:0 +X 1195 . A <*> 0 . DP=26;I16=14,12,0,0,917,33253,0,0,1560,93600,0,0,466,10362,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,177:6:0 0,27,235:9:0 +X 1196 . C <*> 0 . DP=25;I16=13,12,0,0,921,34209,0,0,1500,90000,0,0,466,10334,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,187:6:0 0,27,236:9:0 +X 1197 . C <*> 0 . DP=24;I16=12,12,0,0,906,34862,0,0,1440,86400,0,0,464,10184,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,186:6:0 0,24,233:8:0 +X 1198 . A <*> 0 . DP=24;I16=12,12,0,0,937,36815,0,0,1440,86400,0,0,461,10013,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,190:6:0 0,24,245:8:0 +X 1199 . G <*> 0 . DP=24;I16=12,12,0,0,879,33035,0,0,1440,86400,0,0,457,9821,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,163:6:0 0,24,221:8:0 +X 1200 . T <*> 0 . DP=24;I16=11,12,0,0,895,35141,0,0,1380,82800,0,0,428,9032,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,176:5:0 0,24,247:8:0 +X 1201 . T <*> 0 . DP=24;I16=12,12,0,0,889,33727,0,0,1440,86400,0,0,449,9521,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,177:6:0 0,24,238:8:0 +X 1202 . C <*> 0 . DP=25;I16=13,12,0,0,929,35121,0,0,1500,90000,0,0,445,9413,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,175:6:0 0,24,230:8:0 +X 1203 . A <*> 0 . DP=25;I16=13,12,0,0,943,36107,0,0,1500,90000,0,0,442,9334,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,184:6:0 0,24,241:8:0 +X 1204 . G <*> 0 . DP=24;I16=13,11,0,0,876,33106,0,0,1440,86400,0,0,439,9235,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,174:6:0 0,21,218:7:0 +X 1205 . C <*> 0 . DP=24;I16=13,11,0,0,891,33869,0,0,1440,86400,0,0,436,9166,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,176:6:0 0,21,217:7:0 +X 1206 . A <*> 0 . DP=23;I16=13,10,0,0,846,31744,0,0,1380,82800,0,0,434,9126,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,179:6:0 0,21,212:7:0 +X 1207 . T <*> 0 . DP=23;I16=13,9,0,0,819,30877,0,0,1320,79200,0,0,407,8489,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,254:10:0 0,18,189:6:0 0,18,194:6:0 +X 1208 . C <*> 0 . DP=24;I16=14,10,0,0,910,35236,0,0,1440,86400,0,0,429,9079,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,190:7:0 0,21,217:7:0 +X 1209 . C T,<*> 0 . DP=24;I16=14,9,0,1,869,33481,21,441,1380,82800,60,3600,408,8710,19,361;QS=2.91393,0.0860656,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,30,255,30,255,255:10:0 0,0,153,18,156,166:7:1 0,21,209,21,209,209:7:0 +X 1210 . C <*> 0 . DP=24;I16=14,10,0,0,915,35713,0,0,1440,86400,0,0,425,9091,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,199:7:0 0,21,209:7:0 +X 1211 . T <*> 0 . DP=24;I16=14,10,0,0,905,34669,0,0,1440,86400,0,0,423,9139,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,213:7:0 0,21,214:7:0 +X 1212 . A <*> 0 . DP=24;I16=14,10,0,0,850,30690,0,0,1440,86400,0,0,421,9215,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,246:10:0 0,21,190:7:0 0,21,204:7:0 +X 1213 . A <*> 0 . DP=24;I16=14,10,0,0,852,31192,0,0,1440,86400,0,0,418,9268,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,21,197:7:0 0,21,195:7:0 +X 1214 . C <*> 0 . DP=23;I16=13,10,0,0,851,32099,0,0,1380,82800,0,0,415,9295,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,186:7:0 0,18,184:6:0 +X 1215 . T <*> 0 . DP=23;I16=13,9,0,0,839,32475,0,0,1320,79200,0,0,386,8668,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,211:7:0 0,15,172:5:0 +X 1216 . C <*> 0 . DP=23;I16=13,10,0,0,863,32923,0,0,1380,82800,0,0,406,9260,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,196:7:0 0,18,172:6:0 +X 1217 . A <*> 0 . DP=22;I16=12,10,0,0,820,30926,0,0,1320,79200,0,0,402,9244,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,172:6:0 0,18,191:6:0 +X 1218 . A <*> 0 . DP=22;I16=12,10,0,0,764,27286,0,0,1320,79200,0,0,398,9244,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,145:6:0 0,18,184:6:0 +X 1219 . A <*> 0 . DP=21;I16=12,9,0,0,803,31119,0,0,1260,75600,0,0,395,9259,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,175:6:0 0,15,173:5:0 +X 1220 . A <*> 0 . DP=21;I16=12,9,0,0,752,27700,0,0,1260,75600,0,0,392,9288,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,18,167:6:0 0,15,167:5:0 +X 1221 . A <*> 0 . DP=20;I16=12,8,0,0,722,26564,0,0,1200,72000,0,0,390,9330,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,147:5:0 0,15,157:5:0 +X 1222 . T <*> 0 . DP=18;I16=10,8,0,0,666,25034,0,0,1080,64800,0,0,389,9333,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,245:9:0 0,15,143:5:0 0,12,142:4:0 +X 1223 . T <*> 0 . DP=17;I16=9,7,0,0,574,21262,0,0,960,57600,0,0,364,8720,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,232:9:0 0,12,122:4:0 0,9,120:3:0 +X 1224 . C <*> 0 . DP=19;I16=10,7,0,0,639,24429,0,0,1020,61200,0,0,364,8740,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,128:4:0 0,9,112:3:0 +X 1225 . A <*> 0 . DP=19;I16=10,9,0,0,713,27139,0,0,1109,65641,0,0,395,9419,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,137:5:0 0,12,145:4:0 +X 1226 . A <*> 0 . DP=19;I16=10,9,0,0,688,25468,0,0,1109,65641,0,0,397,9469,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,127:5:0 0,12,147:4:0 +X 1227 . A <*> 0 . DP=19;I16=10,9,0,0,698,26104,0,0,1109,65641,0,0,399,9531,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,133:5:0 0,12,146:4:0 +X 1228 . A <*> 0 . DP=19;I16=10,9,0,0,705,26721,0,0,1109,65641,0,0,399,9505,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,143:5:0 0,12,145:4:0 +X 1229 . A <*> 0 . DP=18;I16=10,8,0,0,693,26891,0,0,1049,62041,0,0,400,9490,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,123:4:0 0,12,138:4:0 +X 1230 . T <*> 0 . DP=18;I16=10,8,0,0,643,23601,0,0,1049,62041,0,0,401,9485,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,30,245:10:0 0,12,115:4:0 0,12,144:4:0 +X 1231 . C <*> 0 . DP=18;I16=10,7,0,0,663,26041,0,0,1020,61200,0,0,390,9320,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,98:3:0 0,12,138:4:0 +X 1232 . T <*> 0 . DP=18;I16=10,8,0,0,683,26261,0,0,1049,62041,0,0,401,9409,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,133:4:0 0,12,129:4:0 +X 1233 . G <*> 0 . DP=18;I16=10,8,0,0,657,24509,0,0,1049,62041,0,0,401,9389,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,124:4:0 0,12,129:4:0 +X 1234 . A <*> 0 . DP=19;I16=10,8,0,0,677,26177,0,0,1080,64800,0,0,386,9134,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,101:3:0 0,12,144:4:0 +X 1235 . A <*> 0 . DP=19;I16=10,9,0,0,697,26363,0,0,1109,65641,0,0,400,9282,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,129:4:0 0,12,140:4:0 +X 1236 . A <*> 0 . DP=19;I16=10,9,0,0,671,24693,0,0,1109,65641,0,0,398,9148,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,103:4:0 0,12,136:4:0 +X 1237 . T <*> 0 . DP=19;I16=9,9,0,0,649,24061,0,0,1049,62041,0,0,370,8356,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,98:3:0 0,12,135:4:0 +X 1238 . C <*> 0 . DP=20;I16=11,9,0,0,733,27709,0,0,1169,69241,0,0,391,8783,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,104:4:0 0,12,145:4:0 +X 1239 . C <*> 0 . DP=20;I16=10,9,0,0,672,24596,0,0,1109,65641,0,0,363,7981,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,76:3:0 0,12,124:4:0 +X 1240 . C <*> 0 . DP=20;I16=11,9,0,0,723,26895,0,0,1169,69241,0,0,385,8451,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,118:4:0 0,12,129:4:0 +X 1241 . A <*> 0 . DP=20;I16=11,9,0,0,719,26575,0,0,1169,69241,0,0,382,8318,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,104:4:0 0,12,141:4:0 +X 1242 . A <*> 0 . DP=21;I16=12,9,0,0,749,27599,0,0,1229,72841,0,0,379,8207,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,109:4:0 0,15,153:5:0 +X 1243 . A <*> 0 . DP=21;I16=12,9,0,0,738,26862,0,0,1229,72841,0,0,377,8119,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,110:4:0 0,15,158:5:0 +X 1244 . C <*> 0 . DP=21;I16=12,8,0,0,670,22952,0,0,1169,69241,0,0,365,7955,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,101:4:0 0,15,148:5:0 +X 1245 . G <*> 0 . DP=21;I16=12,9,0,0,657,21627,0,0,1229,72841,0,0,373,8015,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,245:12:0 0,12,95:4:0 0,15,158:5:0 +X 1246 . C <*> 0 . DP=21;I16=12,9,0,0,652,21348,0,0,1229,72841,0,0,370,7948,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,252:12:0 0,12,95:4:0 0,15,146:5:0 +X 1247 . G <*> 0 . DP=20;I16=11,9,0,0,655,22291,0,0,1169,69241,0,0,367,7853,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,87:4:0 0,15,150:5:0 +X 1248 . C <*> 0 . DP=20;I16=10,8,0,0,659,25037,0,0,1080,64800,0,0,314,6530,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,90:3:0 0,15,156:5:0 +X 1249 . C <*> 0 . DP=21;I16=12,9,0,0,772,28954,0,0,1229,72841,0,0,360,7680,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,111:4:0 0,15,166:5:0 +X 1250 . A <*> 0 . DP=21;I16=12,9,0,0,757,27599,0,0,1229,72841,0,0,356,7554,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,114:4:0 0,15,161:5:0 +X 1251 . A <*> 0 . DP=21;I16=12,9,0,0,758,27890,0,0,1229,72841,0,0,352,7452,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,115:4:0 0,15,174:5:0 +X 1252 . T <*> 0 . DP=21;I16=12,9,0,0,758,27574,0,0,1229,72841,0,0,348,7374,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,124:4:0 0,15,159:5:0 +X 1253 . A <*> 0 . DP=20;I16=12,8,0,0,718,26292,0,0,1169,69241,0,0,345,7319,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,127:4:0 0,12,144:4:0 +X 1254 . A <*> 0 . DP=20;I16=12,8,0,0,781,30817,0,0,1169,69241,0,0,342,7286,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,134:4:0 0,12,156:4:0 +X 1255 . G <*> 0 . DP=21;I16=12,9,0,0,785,30039,0,0,1229,72841,0,0,339,7275,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,128:4:0 0,15,169:5:0 +X 1256 . C <*> 0 . DP=20;I16=12,8,0,0,742,27910,0,0,1169,69241,0,0,338,7286,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,116:4:0 0,15,165:5:0 +X 1257 . A <*> 0 . DP=20;I16=12,8,0,0,745,28017,0,0,1169,69241,0,0,337,7319,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,132:4:0 0,15,167:5:0 +X 1258 . T <*> 0 . DP=20;I16=12,8,0,0,753,28507,0,0,1169,69241,0,0,336,7374,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,126:4:0 0,15,170:5:0 +X 1259 . T <*> 0 . DP=20;I16=12,8,0,0,690,24762,0,0,1169,69241,0,0,335,7451,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,236:11:0 0,12,128:4:0 0,15,170:5:0 +X 1260 . C <*> 0 . DP=20;I16=12,8,0,0,719,26541,0,0,1169,69241,0,0,333,7499,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,127:4:0 0,15,155:5:0 +X 1261 . C <*> 0 . DP=18;I16=11,6,0,0,602,22374,0,0,989,58441,0,0,308,6940,0,0;QS=3,0;MQSB=0.85832;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,117:4:0 0,9,109:3:0 +X 1262 . C <*> 0 . DP=18;I16=12,6,0,0,653,24345,0,0,1049,62041,0,0,333,7597,0,0;QS=3,0;MQSB=0.85394;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,15,145:5:0 0,9,114:3:0 +X 1263 . T <*> 0 . DP=17;I16=12,5,0,0,654,25656,0,0,989,58441,0,0,335,7645,0,0;QS=3,0;MQSB=0.818731;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,15,158:5:0 0,9,118:3:0 +X 1264 . T <*> 0 . DP=17;I16=12,5,0,0,615,22855,0,0,989,58441,0,0,336,7658,0,0;QS=3,0;MQSB=0.818731;MQ0F=0 PL:DP:DV 0,27,226:9:0 0,15,149:5:0 0,9,114:3:0 +X 1265 . T <*> 0 . DP=17;I16=12,5,0,0,620,23176,0,0,989,58441,0,0,334,7538,0,0;QS=3,0;MQSB=0.818731;MQ0F=0 PL:DP:DV 0,27,232:9:0 0,15,144:5:0 0,9,114:3:0 +X 1266 . G <*> 0 . DP=18;I16=13,5,0,0,675,25765,0,0,1049,62041,0,0,332,7438,0,0;QS=3,0;MQSB=0.814433;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,145:5:0 0,9,114:3:0 +X 1267 . A <*> 0 . DP=18;I16=13,5,0,0,663,24799,0,0,1049,62041,0,0,331,7359,0,0;QS=3,0;MQSB=0.814433;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,15,138:5:0 0,9,114:3:0 +X 1268 . G <*> 0 . DP=18;I16=13,5,0,0,638,23584,0,0,1049,62041,0,0,329,7251,0,0;QS=3,0;MQSB=0.814433;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,112:5:0 0,9,108:3:0 +X 1269 . C <*> 0 . DP=18;I16=13,5,0,0,592,20458,0,0,1049,62041,0,0,327,7163,0,0;QS=3,0;MQSB=0.814433;MQ0F=0 PL:DP:DV 0,30,224:10:0 0,15,130:5:0 0,9,107:3:0 +X 1270 . G <*> 0 . DP=18;I16=13,5,0,0,537,16775,0,0,1049,62041,0,0,325,7095,0,0;QS=3,0;MQSB=0.814433;MQ0F=0 PL:DP:DV 0,30,206:10:0 0,15,104:5:0 0,9,98:3:0 +X 1271 . T <*> 0 . DP=18;I16=12,5,0,0,620,22824,0,0,989,58441,0,0,298,6422,0,0;QS=3,0;MQSB=0.818731;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,15,138:5:0 0,9,109:3:0 +X 1272 . C <*> 0 . DP=17;I16=11,5,0,0,597,22587,0,0,929,54841,0,0,297,6393,0,0;QS=3,0;MQSB=0.823561;MQ0F=0 PL:DP:DV 0,27,251:9:0 0,12,113:4:0 0,9,110:3:0 +X 1273 . A <*> 0 . DP=18;I16=12,6,0,0,633,23063,0,0,1049,62041,0,0,318,6866,0,0;QS=3,0;MQSB=0.85394;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,109:4:0 0,9,113:3:0 +X 1274 . T <*> 0 . DP=17;I16=10,6,0,0,609,23335,0,0,929,54841,0,0,293,6205,0,0;QS=3,0;MQSB=0.863243;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,67:2:0 0,9,115:3:0 +X 1275 . G <*> 0 . DP=17;I16=11,6,0,0,602,21976,0,0,989,58441,0,0,317,6763,0,0;QS=3,0;MQSB=0.85832;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,87:3:0 0,9,112:3:0 +X 1276 . T <*> 0 . DP=17;I16=11,6,0,0,587,20925,0,0,989,58441,0,0,316,6714,0,0;QS=3,0;MQSB=0.85832;MQ0F=0 PL:DP:DV 0,33,248:11:0 0,9,94:3:0 0,9,110:3:0 +X 1277 . C <*> 0 . DP=18;I16=11,7,0,0,590,20126,0,0,1049,62041,0,0,314,6634,0,0;QS=3,0;MQSB=0.883327;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,85:3:0 0,9,106:3:0 +X 1278 . G <*> 0 . DP=18;I16=11,7,0,0,603,20675,0,0,1049,62041,0,0,313,6575,0,0;QS=3,0;MQSB=0.883327;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,77:3:0 0,9,96:3:0 +X 1279 . G <*> 0 . DP=18;I16=11,7,0,0,646,23662,0,0,1049,62041,0,0,312,6538,0,0;QS=3,0;MQSB=0.883327;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,85:3:0 0,9,113:3:0 +X 1280 . T <*> 0 . DP=18;I16=10,7,0,0,558,19192,0,0,989,58441,0,0,296,6298,0,0;QS=3,0;MQSB=0.887766;MQ0F=0 PL:DP:DV 0,33,249:11:0 0,9,86:3:0 0,9,97:3:0 +X 1281 . G <*> 0 . DP=17;I16=10,6,0,0,564,21244,0,0,929,54841,0,0,270,5658,0,0;QS=3,0;MQSB=0.863243;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,85:3:0 0,9,103:3:0 +X 1282 . C <*> 0 . DP=18;I16=10,8,0,0,654,24308,0,0,1049,62041,0,0,294,6286,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,94:3:0 0,12,131:4:0 +X 1283 . T <*> 0 . DP=18;I16=10,8,0,0,677,26313,0,0,1049,62041,0,0,294,6308,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,83:3:0 0,12,154:4:0 +X 1284 . T <*> 0 . DP=18;I16=10,8,0,0,631,22949,0,0,1049,62041,0,0,293,6301,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,9,92:3:0 0,12,145:4:0 +X 1285 . G <*> 0 . DP=18;I16=10,7,0,0,657,25545,0,0,989,58441,0,0,267,5691,0,0;QS=3,0;MQSB=0.887766;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,94:3:0 0,12,145:4:0 +X 1286 . G <*> 0 . DP=18;I16=10,8,0,0,650,24684,0,0,1049,62041,0,0,291,6353,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,78:3:0 0,12,148:4:0 +X 1287 . A <*> 0 . DP=17;I16=9,8,0,0,609,22229,0,0,989,58441,0,0,291,6411,0,0;QS=3,0;MQSB=0.91051;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,91:3:0 0,12,137:4:0 +X 1288 . A <*> 0 . DP=17;I16=9,8,0,0,605,22315,0,0,989,58441,0,0,290,6438,0,0;QS=3,0;MQSB=0.91051;MQ0F=0 PL:DP:DV 0,30,245:10:0 0,9,103:3:0 0,12,140:4:0 +X 1289 . T <*> 0 . DP=18;I16=10,8,0,0,637,23207,0,0,1049,62041,0,0,289,6483,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,99:3:0 0,12,141:4:0 +X 1290 . G <*> 0 . DP=15;I16=9,6,0,0,559,21163,0,0,869,51241,0,0,292,6544,0,0;QS=3,0;MQSB=0.868815;MQ0F=0 PL:DP:DV 0,27,242:9:0 0,9,97:3:0 0,9,106:3:0 +X 1291 . T <*> 0 . DP=15;I16=9,6,0,0,547,20303,0,0,869,51241,0,0,295,6619,0,0;QS=3,0;MQSB=0.868815;MQ0F=0 PL:DP:DV 0,27,225:9:0 0,9,91:3:0 0,9,117:3:0 +X 1292 . T <*> 0 . DP=15;I16=9,6,0,0,559,21121,0,0,869,51241,0,0,297,6657,0,0;QS=3,0;MQSB=0.868815;MQ0F=0 PL:DP:DV 0,27,236:9:0 0,9,95:3:0 0,9,113:3:0 +X 1293 . T <*> 0 . DP=15;I16=9,6,0,0,578,22428,0,0,869,51241,0,0,299,6707,0,0;QS=3,0;MQSB=0.868815;MQ0F=0 PL:DP:DV 0,27,242:9:0 0,9,100:3:0 0,9,116:3:0 +X 1294 . G <*> 0 . DP=16;I16=9,7,0,0,606,23572,0,0,929,54841,0,0,301,6769,0,0;QS=3,0;MQSB=0.892753;MQ0F=0 PL:DP:DV 0,27,254:9:0 0,12,110:4:0 0,9,119:3:0 +X 1295 . G <*> 0 . DP=16;I16=9,7,0,0,567,21419,0,0,929,54841,0,0,304,6844,0,0;QS=3,0;MQSB=0.892753;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,12,102:4:0 0,9,114:3:0 +X 1296 . G <*> 0 . DP=16;I16=8,7,0,0,518,19300,0,0,869,51241,0,0,294,6740,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,9,89:3:0 0,9,114:3:0 +X 1297 . G <*> 0 . DP=18;I16=9,8,0,0,551,19323,0,0,958,55682,0,0,322,7444,0,0;QS=3,0;MQSB=0.998843;MQ0F=0 PL:DP:DV 0,30,219:10:0 0,9,86:3:0 0,12,133:4:0 +X 1298 . T <*> 0 . DP=18;I16=10,8,0,0,615,22371,0,0,1018,59282,0,0,336,7638,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,30,233:10:0 0,12,105:4:0 0,12,138:4:0 +X 1299 . T <*> 0 . DP=18;I16=9,8,0,0,619,23135,0,0,958,55682,0,0,328,7548,0,0;QS=3,0;MQSB=0.998843;MQ0F=0 PL:DP:DV 0,30,242:10:0 0,9,97:3:0 0,12,136:4:0 +X 1300 . T <*> 0 . DP=18;I16=10,8,0,0,631,23107,0,0,1018,59282,0,0,338,7638,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,30,235:10:0 0,12,121:4:0 0,12,136:4:0 +X 1301 . T G,<*> 0 . DP=18;I16=8,8,1,0,599,22623,18,324,929,54841,29,841,314,7040,25,625;QS=2.9434,0.0566038,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.998843;BQB=1;MQ0F=0 PL:DP:DV 0,9,213,24,216,222:9:1 0,12,126,12,126,126:4:0 0,12,135,12,135,135:4:0 +X 1302 . G <*> 0 . DP=17;I16=9,8,0,0,624,23544,0,0,958,55682,0,0,341,7709,0,0;QS=3,0;MQSB=0.998843;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,12,127:4:0 0,12,140:4:0 +X 1303 . G <*> 0 . DP=17;I16=9,8,0,0,582,21200,0,0,958,55682,0,0,342,7718,0,0;QS=3,0;MQSB=0.998843;MQ0F=0 PL:DP:DV 0,27,217:9:0 0,12,125:4:0 0,12,138:4:0 +X 1304 . A <*> 0 . DP=18;I16=10,8,0,0,652,24124,0,0,1018,59282,0,0,343,7741,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,27,218:9:0 0,12,131:4:0 0,15,169:5:0 +X 1305 . T <*> 0 . DP=18;I16=10,8,0,0,685,26381,0,0,1018,59282,0,0,345,7779,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,12,122:4:0 0,15,174:5:0 +X 1306 . T <*> 0 . DP=18;I16=9,8,0,0,644,24628,0,0,958,55682,0,0,345,7829,0,0;QS=3,0;MQSB=0.998843;MQ0F=0 PL:DP:DV 0,27,236:9:0 0,9,106:3:0 0,15,168:5:0 +X 1307 . T <*> 0 . DP=17;I16=9,8,0,0,628,23746,0,0,958,55682,0,0,348,7902,0,0;QS=3,0;MQSB=0.998843;MQ0F=0 PL:DP:DV 0,27,226:9:0 0,9,104:3:0 0,15,167:5:0 +X 1308 . A <*> 0 . DP=19;I16=9,10,0,0,690,25500,0,0,1078,62882,0,0,350,7938,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,30,236:10:0 0,12,127:4:0 0,15,173:5:0 +X 1309 . C <*> 0 . DP=19;I16=9,9,0,0,698,27148,0,0,1049,62041,0,0,342,7818,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,106:3:0 0,15,169:5:0 +X 1310 . A <*> 0 . DP=19;I16=9,10,0,0,751,29953,0,0,1078,62882,0,0,356,7958,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,132:4:0 0,15,183:5:0 +X 1311 . G <*> 0 . DP=19;I16=9,10,0,0,742,29384,0,0,1078,62882,0,0,359,7995,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,128:4:0 0,15,174:5:0 +X 1312 . C <*> 0 . DP=19;I16=9,10,0,0,717,27783,0,0,1078,62882,0,0,362,8050,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,115:4:0 0,15,166:5:0 +X 1313 . T <*> 0 . DP=19;I16=9,10,0,0,751,30061,0,0,1078,62882,0,0,364,8074,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,135:4:0 0,15,175:5:0 +X 1314 . T <*> 0 . DP=19;I16=9,10,0,0,707,26983,0,0,1078,62882,0,0,366,8118,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,30,245:10:0 0,12,134:4:0 0,15,174:5:0 +X 1315 . T <*> 0 . DP=19;I16=9,10,0,0,717,27491,0,0,1078,62882,0,0,367,8131,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,12,132:4:0 0,15,174:5:0 +X 1316 . G <*> 0 . DP=21;I16=10,11,0,0,776,29502,0,0,1198,70082,0,0,368,8162,0,0;QS=3,0;MQSB=0.99938;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,128:4:0 0,18,188:6:0 +X 1317 . G <*> 0 . DP=21;I16=10,11,0,0,751,27855,0,0,1198,70082,0,0,371,8213,0,0;QS=3,0;MQSB=0.99938;MQ0F=0 PL:DP:DV 0,33,253:11:0 0,12,130:4:0 0,18,179:6:0 +X 1318 . G <*> 0 . DP=21;I16=10,11,0,0,749,27663,0,0,1198,70082,0,0,372,8188,0,0;QS=3,0;MQSB=0.99938;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,130:4:0 0,18,184:6:0 +X 1319 . A <*> 0 . DP=21;I16=10,11,0,0,768,28390,0,0,1198,70082,0,0,373,8189,0,0;QS=3,0;MQSB=0.99938;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,124:4:0 0,18,186:6:0 +X 1320 . C <*> 0 . DP=21;I16=10,11,0,0,728,25496,0,0,1198,70082,0,0,373,8165,0,0;QS=3,0;MQSB=0.99938;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,113:4:0 0,18,161:6:0 +X 1321 . G <*> 0 . DP=22;I16=10,12,0,0,762,27412,0,0,1289,76441,0,0,374,8164,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,33,244:11:0 0,9,104:3:0 0,24,208:8:0 +X 1322 . C <*> 0 . DP=22;I16=10,12,0,0,852,33528,0,0,1289,76441,0,0,377,8187,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,111:3:0 0,24,225:8:0 +X 1323 . T <*> 0 . DP=22;I16=10,12,0,0,874,35152,0,0,1289,76441,0,0,379,8185,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,112:3:0 0,24,237:8:0 +X 1324 . C <*> 0 . DP=21;I16=9,12,0,0,793,30585,0,0,1229,72841,0,0,381,8157,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,109:3:0 0,24,218:8:0 +X 1325 . A <*> 0 . DP=21;I16=9,12,0,0,782,29430,0,0,1229,72841,0,0,383,8153,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,105:3:0 0,24,218:8:0 +X 1326 . A <*> 0 . DP=21;I16=9,12,0,0,791,30479,0,0,1229,72841,0,0,385,8173,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,9,108:3:0 0,24,230:8:0 +X 1327 . C <*> 0 . DP=23;I16=11,12,0,0,834,31048,0,0,1349,80041,0,0,387,8217,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,99:3:0 0,27,237:9:0 +X 1328 . C <*> 0 . DP=23;I16=11,12,0,0,878,33972,0,0,1349,80041,0,0,391,8287,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,105:3:0 0,27,254:9:0 +X 1329 . T <*> 0 . DP=23;I16=11,12,0,0,882,34756,0,0,1349,80041,0,0,395,8385,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,112:3:0 0,27,255:9:0 +X 1330 . G <*> 0 . DP=23;I16=11,12,0,0,856,32638,0,0,1349,80041,0,0,398,8460,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,101:3:0 0,27,241:9:0 +X 1331 . T <*> 0 . DP=23;I16=11,12,0,0,847,31785,0,0,1349,80041,0,0,400,8512,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,106:3:0 0,27,247:9:0 +X 1332 . A <*> 0 . DP=23;I16=11,12,0,0,826,30264,0,0,1349,80041,0,0,402,8592,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,252:11:0 0,9,104:3:0 0,27,238:9:0 +X 1333 . C <*> 0 . DP=23;I16=11,12,0,0,836,30928,0,0,1349,80041,0,0,404,8700,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,101:3:0 0,27,236:9:0 +X 1334 . C <*> 0 . DP=22;I16=11,11,0,0,830,32380,0,0,1289,76441,0,0,405,8733,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,107:3:0 0,27,238:9:0 +X 1335 . T <*> 0 . DP=22;I16=11,11,0,0,877,35371,0,0,1289,76441,0,0,406,8788,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,113:3:0 0,27,253:9:0 +X 1336 . C <*> 0 . DP=25;I16=12,12,0,0,890,33648,0,0,1378,80882,0,0,398,8784,0,0;QS=3,0;MQSB=0.786628;MQ0F=0 PL:DP:DV 0,33,250:11:0 0,12,131:4:0 0,27,237:9:0 +X 1337 . A <*> 0 . DP=26;I16=13,13,0,0,941,34611,0,0,1498,88082,0,0,411,8967,0,0;QS=3,0;MQSB=0.800737;MQ0F=0 PL:DP:DV 0,33,249:11:0 0,15,152:5:0 0,30,247:10:0 +X 1338 . A <*> 0 . DP=26;I16=12,14,0,0,982,37358,0,0,1498,88082,0,0,416,9048,0,0;QS=3,0;MQSB=0.771623;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,153:5:0 0,30,255:10:0 +X 1339 . T <*> 0 . DP=27;I16=12,15,0,0,989,36855,0,0,1558,91682,0,0,422,9160,0,0;QS=3,0;MQSB=0.765017;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,151:5:0 0,33,255:11:0 +X 1340 . A <*> 0 . DP=27;I16=11,15,0,0,937,34141,0,0,1498,88082,0,0,425,9289,0,0;QS=3,0;MQSB=0.738577;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,15,149:5:0 0,33,254:11:0 +X 1341 . A <*> 0 . DP=27;I16=12,14,0,0,929,33961,0,0,1498,88082,0,0,410,8810,0,0;QS=3,0;MQSB=0.771623;MQ0F=0 PL:DP:DV 0,30,245:10:0 0,15,141:5:0 0,33,255:11:0 +X 1342 . A <*> 0 . DP=27;I16=12,15,0,0,951,34575,0,0,1558,91682,0,0,439,9499,0,0;QS=3,0;MQSB=0.765017;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,15,159:5:0 0,33,249:11:0 +X 1343 . C <*> 0 . DP=25;I16=10,15,0,0,902,33364,0,0,1469,87241,0,0,445,9593,0,0;QS=3,0;MQSB=0.9171;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,140:5:0 0,30,233:10:0 +X 1344 . C <*> 0 . DP=26;I16=10,16,0,0,985,37915,0,0,1529,90841,0,0,451,9715,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,163:6:0 0,30,238:10:0 +X 1345 . T <*> 0 . DP=26;I16=10,16,0,0,1004,39262,0,0,1529,90841,0,0,458,9866,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,182:6:0 0,30,242:10:0 +X 1346 . G <*> 0 . DP=26;I16=10,16,0,0,1003,38983,0,0,1529,90841,0,0,465,10047,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,172:6:0 0,30,239:10:0 +X 1347 . A <*> 0 . DP=26;I16=10,16,0,0,995,38409,0,0,1529,90841,0,0,470,10156,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,177:6:0 0,30,243:10:0 +X 1348 . T <*> 0 . DP=26;I16=10,16,0,0,988,38126,0,0,1529,90841,0,0,474,10242,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,18,185:6:0 0,30,251:10:0 +X 1349 . T <*> 0 . DP=26;I16=9,15,0,0,905,34409,0,0,1409,83641,0,0,454,9730,0,0;QS=3,0;MQSB=0.904837;MQ0F=0 PL:DP:DV 0,24,225:8:0 0,18,176:6:0 0,30,248:10:0 +X 1350 . T <*> 0 . DP=26;I16=10,16,0,0,975,36909,0,0,1498,88082,0,0,485,10495,0,0;QS=3,0;MQSB=0.700784;MQ0F=0 PL:DP:DV 0,27,242:9:0 0,21,195:7:0 0,30,249:10:0 +X 1351 . T <*> 0 . DP=26;I16=10,16,0,0,956,35602,0,0,1498,88082,0,0,491,10663,0,0;QS=3,0;MQSB=0.700784;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,21,193:7:0 0,30,240:10:0 +X 1352 . A <*> 0 . DP=26;I16=10,16,0,0,901,31965,0,0,1498,88082,0,0,496,10810,0,0;QS=3,0;MQSB=0.700784;MQ0F=0 PL:DP:DV 0,27,250:9:0 0,21,180:7:0 0,30,211:10:0 +X 1353 . A <*> 0 . DP=26;I16=10,16,0,0,927,33583,0,0,1498,88082,0,0,499,10885,0,0;QS=3,0;MQSB=0.700784;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,21,187:7:0 0,30,224:10:0 +X 1354 . A <*> 0 . DP=26;I16=10,16,0,0,927,33621,0,0,1498,88082,0,0,502,10986,0,0;QS=3,0;MQSB=0.700784;MQ0F=0 PL:DP:DV 0,27,237:9:0 0,21,190:7:0 0,30,223:10:0 +X 1355 . A <*> 0 . DP=26;I16=10,16,0,0,924,33736,0,0,1498,88082,0,0,505,11113,0,0;QS=3,0;MQSB=0.700784;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,21,186:7:0 0,30,227:10:0 +X 1356 . A <*> 0 . DP=25;I16=10,15,0,0,916,34050,0,0,1438,84482,0,0,509,11265,0,0;QS=3,0;MQSB=0.707404;MQ0F=0 PL:DP:DV 0,27,249:9:0 0,21,178:7:0 0,27,226:9:0 +X 1357 . A <*> 0 . DP=25;I16=9,15,0,0,949,38007,0,0,1378,80882,0,0,488,10816,0,0;QS=3,0;MQSB=0.67032;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,21,193:7:0 0,24,217:8:0 +X 1358 . G <*> 0 . DP=25;I16=9,15,0,0,873,32435,0,0,1378,80882,0,0,491,10967,0,0;QS=3,0;MQSB=0.67032;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,21,172:7:0 0,24,188:8:0 +X 1359 . T <*> 0 . DP=25;I16=9,15,0,0,857,31139,0,0,1378,80882,0,0,494,11144,0,0;QS=3,0;MQSB=0.67032;MQ0F=0 PL:DP:DV 0,27,232:9:0 0,21,184:7:0 0,24,196:8:0 +X 1360 . T <*> 0 . DP=25;I16=9,15,0,0,879,32419,0,0,1378,80882,0,0,497,11347,0,0;QS=3,0;MQSB=0.67032;MQ0F=0 PL:DP:DV 0,27,248:9:0 0,21,184:7:0 0,24,192:8:0 +X 1361 . T <*> 0 . DP=27;I16=9,17,0,0,936,34238,0,0,1498,88082,0,0,500,11576,0,0;QS=3,0;MQSB=0.657209;MQ0F=0 PL:DP:DV 0,27,234:9:0 0,24,201:8:0 0,27,206:9:0 +X 1362 . G <*> 0 . DP=26;I16=9,17,0,0,973,36785,0,0,1498,88082,0,0,502,11680,0,0;QS=3,0;MQSB=0.657209;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,24,202:8:0 0,27,207:9:0 +X 1363 . G <*> 0 . DP=25;I16=8,17,0,0,936,35390,0,0,1438,84482,0,0,504,11756,0,0;QS=3,0;MQSB=0.612391;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,21,181:7:0 0,27,202:9:0 +X 1364 . G <*> 0 . DP=25;I16=8,17,0,0,902,32840,0,0,1438,84482,0,0,504,11752,0,0;QS=3,0;MQSB=0.612391;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,21,184:7:0 0,27,200:9:0 +X 1365 . G <*> 0 . DP=26;I16=9,17,0,0,946,35224,0,0,1498,88082,0,0,503,11717,0,0;QS=3,0;MQSB=0.657209;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,24,190:8:0 0,27,202:9:0 +X 1366 . G <*> 0 . DP=25;I16=8,15,0,0,840,31058,0,0,1318,77282,0,0,454,10450,0,0;QS=3,0;MQSB=0.625784;MQ0F=0 PL:DP:DV 0,21,215:7:0 0,21,181:7:0 0,27,199:9:0 +X 1367 . G C,<*> 0 . DP=25;I16=7,16,0,1,836,30888,27,729,1349,80041,60,3600,472,11152,15,225;QS=2.91641,0.0835913,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.864405;BQB=1;MQ0F=0 PL:DP:DV 0,24,236,24,236,236:8:0 0,21,179,21,179,179:7:0 0,0,171,24,174,189:9:1 +X 1368 . A <*> 0 . DP=26;I16=8,17,0,0,869,30839,0,0,1438,84482,0,0,481,11095,0,0;QS=3,0;MQSB=0.612391;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,21,180:7:0 0,27,197:9:0 +X 1369 . T <*> 0 . DP=26;I16=8,18,0,0,902,32160,0,0,1498,88082,0,0,508,11758,0,0;QS=3,0;MQSB=0.606531;MQ0F=0 PL:DP:DV 0,27,242:9:0 0,24,197:8:0 0,27,194:9:0 +X 1370 . T <*> 0 . DP=27;I16=8,17,0,0,926,34736,0,0,1438,84482,0,0,458,10466,0,0;QS=3,0;MQSB=0.612391;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,21,195:7:0 0,27,215:9:0 +X 1371 . C <*> 0 . DP=27;I16=8,19,0,0,929,33255,0,0,1558,91682,0,0,509,11695,0,0;QS=3,0;MQSB=0.601139;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,24,196:8:0 0,30,196:10:0 +X 1372 . C <*> 0 . DP=27;I16=8,19,0,0,954,34882,0,0,1558,91682,0,0,510,11696,0,0;QS=3,0;MQSB=0.601139;MQ0F=0 PL:DP:DV 0,27,251:9:0 0,24,198:8:0 0,30,200:10:0 +X 1373 . C <*> 0 . DP=26;I16=8,17,0,0,892,32692,0,0,1438,84482,0,0,486,11044,0,0;QS=3,0;MQSB=0.612391;MQ0F=0 PL:DP:DV 0,24,243:8:0 0,21,186:7:0 0,30,195:10:0 +X 1374 . C <*> 0 . DP=26;I16=8,17,0,0,953,36553,0,0,1438,84482,0,0,487,11039,0,0;QS=3,0;MQSB=0.612391;MQ0F=0 PL:DP:DV 0,24,249:8:0 0,21,193:7:0 0,30,211:10:0 +X 1375 . T <*> 0 . DP=27;I16=9,18,0,0,1011,38377,0,0,1558,91682,0,0,512,11630,0,0;QS=3,0;MQSB=0.651439;MQ0F=0 PL:DP:DV 0,27,243:9:0 0,24,215:8:0 0,30,215:10:0 +X 1376 . A <*> 0 . DP=27;I16=9,17,0,0,912,32444,0,0,1498,88082,0,0,488,10992,0,0;QS=3,0;MQSB=0.657209;MQ0F=0 PL:DP:DV 0,27,234:9:0 0,21,198:7:0 0,30,195:10:0 +X 1377 . A <*> 0 . DP=26;I16=9,17,0,0,994,38518,0,0,1498,88082,0,0,515,11625,0,0;QS=3,0;MQSB=0.657209;MQ0F=0 PL:DP:DV 0,24,228:8:0 0,24,221:8:0 0,30,228:10:0 +X 1378 . G <*> 0 . DP=26;I16=9,17,0,0,910,33180,0,0,1498,88082,0,0,517,11653,0,0;QS=3,0;MQSB=0.657209;MQ0F=0 PL:DP:DV 0,24,234:8:0 0,24,199:8:0 0,30,197:10:0 +X 1379 . C <*> 0 . DP=26;I16=9,17,0,0,891,31779,0,0,1498,88082,0,0,519,11701,0,0;QS=3,0;MQSB=0.657209;MQ0F=0 PL:DP:DV 0,24,228:8:0 0,24,198:8:0 0,30,193:10:0 +X 1380 . C <*> 0 . DP=26;I16=9,17,0,0,925,33925,0,0,1498,88082,0,0,520,11720,0,0;QS=3,0;MQSB=0.657209;MQ0F=0 PL:DP:DV 0,24,226:8:0 0,24,202:8:0 0,30,209:10:0 +X 1381 . C <*> 0 . DP=28;I16=10,18,0,0,878,28560,0,0,1618,95282,0,0,521,11761,0,0;QS=3,0;MQSB=0.689069;MQ0F=0 PL:DP:DV 0,24,211:8:0 0,24,177:8:0 0,36,208:12:0 +X 1382 . G <*> 0 . DP=28;I16=8,18,0,0,905,32553,0,0,1529,90841,0,0,482,10912,0,0;QS=3,0;MQSB=0.882497;MQ0F=0 PL:DP:DV 0,24,213:8:0 0,18,152:6:0 0,36,243:12:0 +X 1383 . C <*> 0 . DP=27;I16=10,16,0,0,897,32373,0,0,1498,88082,0,0,502,11242,0,0;QS=3,0;MQSB=0.700784;MQ0F=0 PL:DP:DV 0,24,225:8:0 0,21,163:7:0 0,33,241:11:0 +X 1384 . C <*> 0 . DP=28;I16=11,17,0,0,980,35558,0,0,1618,95282,0,0,529,11885,0,0;QS=3,0;MQSB=0.726331;MQ0F=0 PL:DP:DV 0,27,248:9:0 0,24,184:8:0 0,33,239:11:0 +X 1385 . A <*> 0 . DP=30;I16=11,18,0,0,949,33215,0,0,1678,98882,0,0,508,11356,0,0;QS=3,0;MQSB=0.720887;MQ0F=0 PL:DP:DV 0,30,232:10:0 0,27,185:9:0 0,30,234:10:0 +X 1386 . C <*> 0 . DP=30;I16=11,19,0,0,1088,39938,0,0,1738,102482,0,0,537,12011,0,0;QS=3,0;MQSB=0.715831;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,27,218:9:0 0,33,255:11:0 +X 1387 . C <*> 0 . DP=31;I16=12,19,0,0,1101,40297,0,0,1798,106082,0,0,540,12022,0,0;QS=3,0;MQSB=0.743137;MQ0F=0 PL:DP:DV 0,33,250:11:0 0,27,219:9:0 0,33,252:11:0 +X 1388 . C <*> 0 . DP=31;I16=11,19,0,0,999,34081,0,0,1769,105241,0,0,519,11439,0,0;QS=3,0;MQSB=0.91982;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,185:8:0 0,33,211:11:0 +X 1389 . G <*> 0 . DP=31;I16=11,19,0,0,1065,39119,0,0,1738,102482,0,0,535,11941,0,0;QS=3,0;MQSB=0.715831;MQ0F=0 PL:DP:DV 0,27,234:9:0 0,30,234:10:0 0,33,255:11:0 +X 1390 . G <*> 0 . DP=31;I16=12,19,0,0,1152,43744,0,0,1798,106082,0,0,555,12241,0,0;QS=3,0;MQSB=0.743137;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,30,245:10:0 0,33,255:11:0 +X 1391 . A <*> 0 . DP=31;I16=12,19,0,0,1241,50255,0,0,1798,106082,0,0,560,12326,0,0;QS=3,0;MQSB=0.743137;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,30,255:10:0 0,33,255:11:0 +X 1392 . G <*> 0 . DP=31;I16=12,19,0,0,1160,44364,0,0,1798,106082,0,0,564,12392,0,0;QS=3,0;MQSB=0.743137;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,30,250:10:0 0,33,255:11:0 +X 1393 . A <*> 0 . DP=31;I16=12,19,0,0,1123,41811,0,0,1798,106082,0,0,568,12490,0,0;QS=3,0;MQSB=0.743137;MQ0F=0 PL:DP:DV 0,30,228:10:0 0,30,255:10:0 0,33,255:11:0 +X 1394 . C <*> 0 . DP=31;I16=12,19,0,0,1139,42555,0,0,1798,106082,0,0,571,12569,0,0;QS=3,0;MQSB=0.743137;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,30,244:10:0 0,33,255:11:0 +X 1395 . A <*> 0 . DP=31;I16=12,19,0,0,1206,48048,0,0,1798,106082,0,0,575,12677,0,0;QS=3,0;MQSB=0.743137;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,240:9:0 0,33,255:11:0 +X 1396 . G <*> 0 . DP=31;I16=12,19,0,0,1196,46882,0,0,1798,106082,0,0,579,12763,0,0;QS=3,0;MQSB=0.743137;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,249:9:0 0,33,255:11:0 +X 1397 . C <*> 0 . DP=31;I16=12,18,0,0,993,33339,0,0,1738,102482,0,0,579,12775,0,0;QS=3,0;MQSB=0.748022;MQ0F=0 PL:DP:DV 0,30,231:10:0 0,27,205:9:0 0,33,217:11:0 +X 1398 . G <*> 0 . DP=30;I16=12,18,0,0,1055,38309,0,0,1738,102482,0,0,584,12826,0,0;QS=3,0;MQSB=0.748022;MQ0F=0 PL:DP:DV 0,33,250:11:0 0,27,229:9:0 0,30,244:10:0 +X 1399 . G <*> 0 . DP=30;I16=12,18,0,0,1132,43666,0,0,1738,102482,0,0,586,12854,0,0;QS=3,0;MQSB=0.748022;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,239:9:0 0,30,255:10:0 +X 1400 . A <*> 0 . DP=30;I16=11,18,0,0,1101,42271,0,0,1678,98882,0,0,563,12289,0,0;QS=3,0;MQSB=0.720887;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,27,239:9:0 0,30,246:10:0 +X 1401 . T <*> 0 . DP=30;I16=12,18,0,0,1130,44170,0,0,1738,102482,0,0,589,12955,0,0;QS=3,0;MQSB=0.748022;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,251:9:0 0,30,255:10:0 +X 1402 . T <*> 0 . DP=31;I16=13,18,0,0,1152,44058,0,0,1798,106082,0,0,589,12977,0,0;QS=3,0;MQSB=0.771348;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,244:9:0 0,30,255:10:0 +X 1403 . T <*> 0 . DP=31;I16=13,18,0,0,1178,45296,0,0,1798,106082,0,0,590,13032,0,0;QS=3,0;MQSB=0.771348;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,249:9:0 0,30,255:10:0 +X 1404 . C <*> 0 . DP=31;I16=13,18,0,0,1102,40838,0,0,1798,106082,0,0,591,13121,0,0;QS=3,0;MQSB=0.771348;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,236:9:0 0,30,244:10:0 +X 1405 . C <*> 0 . DP=30;I16=12,18,0,0,1154,45216,0,0,1738,102482,0,0,593,13243,0,0;QS=3,0;MQSB=0.748022;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,241:9:0 0,27,229:9:0 +X 1406 . T <*> 0 . DP=30;I16=12,18,0,0,1153,44919,0,0,1738,102482,0,0,595,13397,0,0;QS=3,0;MQSB=0.748022;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,248:9:0 0,27,223:9:0 +X 1407 . T <*> 0 . DP=30;I16=11,18,0,0,1074,40182,0,0,1678,98882,0,0,570,12856,0,0;QS=3,0;MQSB=0.720887;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,231:9:0 0,27,215:9:0 +X 1408 . A <*> 0 . DP=30;I16=12,18,0,0,1131,43363,0,0,1738,102482,0,0,596,13592,0,0;QS=3,0;MQSB=0.748022;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,30,244:10:0 0,27,234:9:0 +X 1409 . G <*> 0 . DP=29;I16=12,17,0,0,1082,40752,0,0,1678,98882,0,0,599,13729,0,0;QS=3,0;MQSB=0.753269;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,237:9:0 0,27,204:9:0 +X 1410 . T <*> 0 . DP=29;I16=12,17,0,0,1084,41030,0,0,1678,98882,0,0,601,13841,0,0;QS=3,0;MQSB=0.753269;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,239:9:0 0,27,218:9:0 +X 1411 . T <*> 0 . DP=29;I16=12,17,0,0,958,32550,0,0,1678,98882,0,0,600,13826,0,0;QS=3,0;MQSB=0.753269;MQ0F=0 PL:DP:DV 0,33,250:11:0 0,27,206:9:0 0,27,194:9:0 +X 1412 . A T,<*> 0 . DP=29;I16=11,17,1,0,924,31586,25,625,1649,98041,29,841,573,13159,24,576;QS=2.90842,0.0915751,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.753269;BQB=1;MQ0F=0 PL:DP:DV 0,33,245,33,245,245:11:0 0,2,171,24,174,187:9:1 0,27,192,27,192,192:9:0 +X 1413 . C <*> 0 . DP=29;I16=12,17,0,0,1067,39941,0,0,1678,98882,0,0,591,13521,0,0;QS=3,0;MQSB=0.753269;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,230:9:0 0,27,209:9:0 +X 1414 . T <*> 0 . DP=29;I16=12,17,0,0,1123,44271,0,0,1678,98882,0,0,585,13335,0,0;QS=3,0;MQSB=0.753269;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,236:9:0 0,27,221:9:0 +X 1415 . T <*> 0 . DP=29;I16=12,17,0,0,1000,35254,0,0,1678,98882,0,0,577,13077,0,0;QS=3,0;MQSB=0.753269;MQ0F=0 PL:DP:DV 0,33,246:11:0 0,27,216:9:0 0,27,208:9:0 +X 1416 . A <*> 0 . DP=30;I16=13,17,0,0,1026,36124,0,0,1738,102482,0,0,569,12847,0,0;QS=3,0;MQSB=0.776389;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,208:9:0 0,27,199:9:0 +X 1417 . C <*> 0 . DP=29;I16=13,16,0,0,1111,42941,0,0,1678,98882,0,0,563,12645,0,0;QS=3,0;MQSB=0.781802;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,235:9:0 0,24,211:8:0 +X 1418 . T <*> 0 . DP=29;I16=13,16,0,0,1111,43021,0,0,1678,98882,0,0,557,12471,0,0;QS=3,0;MQSB=0.781802;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,231:9:0 0,24,207:8:0 +X 1419 . A <*> 0 . DP=29;I16=13,16,0,0,1039,38191,0,0,1678,98882,0,0,551,12325,0,0;QS=3,0;MQSB=0.781802;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,222:9:0 0,24,199:8:0 +X 1420 . T <*> 0 . DP=29;I16=13,16,0,0,1039,37885,0,0,1678,98882,0,0,544,12158,0,0;QS=3,0;MQSB=0.781802;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,234:9:0 0,24,185:8:0 +X 1421 . G <*> 0 . DP=31;I16=13,18,0,0,1129,41649,0,0,1798,106082,0,0,536,11970,0,0;QS=3,0;MQSB=0.771348;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,30,247:10:0 0,24,191:8:0 +X 1422 . C <*> 0 . DP=29;I16=13,16,0,0,1075,40645,0,0,1678,98882,0,0,532,11810,0,0;QS=3,0;MQSB=0.781802;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,30,239:10:0 0,18,180:6:0 +X 1423 . T <*> 0 . DP=31;I16=14,17,0,0,1179,45767,0,0,1798,106082,0,0,528,11678,0,0;QS=3,0;MQSB=0.79638;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,36,255:12:0 0,18,183:6:0 +X 1424 . C <*> 0 . DP=30;I16=13,17,0,0,1086,40448,0,0,1738,102482,0,0,527,11575,0,0;QS=3,0;MQSB=0.776389;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,36,255:12:0 0,18,174:6:0 +X 1425 . C <*> 0 . DP=30;I16=13,17,0,0,1124,42974,0,0,1738,102482,0,0,525,11453,0,0;QS=3,0;MQSB=0.776389;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,36,255:12:0 0,18,180:6:0 +X 1426 . T <*> 0 . DP=32;I16=15,17,0,0,1218,47130,0,0,1858,109682,0,0,523,11363,0,0;QS=3,0;MQSB=0.813784;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,36,255:12:0 0,18,188:6:0 +X 1427 . T <*> 0 . DP=32;I16=14,18,0,0,1126,40772,0,0,1827,106923,0,0,524,11306,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,36,255:12:0 0,18,176:6:0 +X 1428 . G <*> 0 . DP=33;I16=15,18,0,0,1188,43596,0,0,1887,110523,0,0,525,11233,0,0;QS=3,0;MQSB=0.930476;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,36,255:12:0 0,18,166:6:0 +X 1429 . G <*> 0 . DP=33;I16=14,18,0,0,1070,37720,0,0,1858,109682,0,0,507,10795,0,0;QS=3,0;MQSB=0.997118;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,33,243:11:0 0,18,148:6:0 +X 1430 . C <*> 0 . DP=33;I16=15,18,0,0,1145,40795,0,0,1887,110523,0,0,529,11193,0,0;QS=3,0;MQSB=0.930476;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,36,247:12:0 0,18,157:6:0 +X 1431 . C <*> 0 . DP=33;I16=15,18,0,0,1160,41686,0,0,1887,110523,0,0,531,11227,0,0;QS=3,0;MQSB=0.930476;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,36,253:12:0 0,18,167:6:0 +X 1432 . A <*> 0 . DP=33;I16=15,18,0,0,1118,39032,0,0,1887,110523,0,0,533,11297,0,0;QS=3,0;MQSB=0.930476;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,36,255:12:0 0,18,169:6:0 +X 1433 . T <*> 0 . DP=34;I16=15,19,0,0,1238,45602,0,0,1947,114123,0,0,535,11403,0,0;QS=3,0;MQSB=0.923533;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,36,255:12:0 0,18,174:6:0 +X 1434 . T <*> 0 . DP=35;I16=15,20,0,0,1269,46757,0,0,2007,117723,0,0,537,11495,0,0;QS=3,0;MQSB=0.916855;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,36,255:12:0 0,18,179:6:0 +X 1435 . T <*> 0 . DP=35;I16=14,20,0,0,1256,46868,0,0,1947,114123,0,0,515,10999,0,0;QS=3,0;MQSB=0.901704;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,36,255:12:0 0,18,180:6:0 +X 1436 . C <*> 0 . DP=34;I16=14,20,0,0,1250,46978,0,0,1947,114123,0,0,544,11790,0,0;QS=3,0;MQSB=0.901704;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,36,255:12:0 0,18,165:6:0 +X 1437 . T <*> 0 . DP=32;I16=13,19,0,0,1222,47206,0,0,1858,109682,0,0,548,11892,0,0;QS=3,0;MQSB=0.993397;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,33,255:11:0 0,15,161:5:0 +X 1438 . C <*> 0 . DP=30;I16=13,17,0,0,1132,43284,0,0,1738,102482,0,0,554,12028,0,0;QS=3,0;MQSB=0.996503;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,30,251:10:0 0,15,159:5:0 +X 1439 . T <*> 0 . DP=30;I16=13,17,0,0,1110,41602,0,0,1738,102482,0,0,560,12196,0,0;QS=3,0;MQSB=0.996503;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,30,255:10:0 0,15,156:5:0 +X 1440 . A <*> 0 . DP=30;I16=12,16,0,0,1062,41028,0,0,1618,95282,0,0,550,12106,0,0;QS=3,0;MQSB=0.995699;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,255:9:0 0,12,144:4:0 +X 1441 . G <*> 0 . DP=30;I16=13,17,0,0,1138,44104,0,0,1738,102482,0,0,574,12576,0,0;QS=3,0;MQSB=0.996503;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,30,244:10:0 0,12,137:4:0 +X 1442 . G <*> 0 . DP=30;I16=13,17,0,0,1064,38534,0,0,1738,102482,0,0,580,12740,0,0;QS=3,0;MQSB=0.996503;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,30,242:10:0 0,12,128:4:0 +X 1443 . T <*> 0 . DP=30;I16=12,17,0,0,1013,36225,0,0,1678,98882,0,0,568,12598,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,30,230:10:0 0,12,133:4:0 +X 1444 . A <*> 0 . DP=30;I16=12,17,0,0,968,33936,0,0,1678,98882,0,0,569,12627,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,27,205:9:0 0,12,132:4:0 +X 1445 . T <*> 0 . DP=30;I16=14,15,0,0,1053,39129,0,0,1678,98882,0,0,585,13161,0,0;QS=3,0;MQSB=0.999762;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,237:9:0 0,15,169:5:0 +X 1446 . T <*> 0 . DP=30;I16=13,16,0,0,1051,38675,0,0,1678,98882,0,0,579,12951,0,0;QS=3,0;MQSB=0.997839;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,229:8:0 0,15,164:5:0 +X 1447 . G <*> 0 . DP=30;I16=14,16,0,0,1110,42692,0,0,1738,102482,0,0,606,13612,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,27,229:9:0 0,15,157:5:0 +X 1448 . G <*> 0 . DP=30;I16=13,16,0,0,1037,37759,0,0,1678,98882,0,0,585,13151,0,0;QS=3,0;MQSB=0.997839;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,217:8:0 0,15,150:5:0 +X 1449 . T <*> 0 . DP=30;I16=14,16,0,0,1051,37869,0,0,1738,102482,0,0,612,13870,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,27,230:9:0 0,15,152:5:0 +X 1450 . A <*> 0 . DP=29;I16=13,15,0,0,1039,38785,0,0,1649,98041,0,0,604,13842,0,0;QS=3,0;MQSB=0.956162;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,224:8:0 0,15,165:5:0 +X 1451 . T <*> 0 . DP=29;I16=13,16,0,0,1046,38586,0,0,1709,101641,0,0,616,14042,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,228:8:0 0,15,158:5:0 +X 1452 . A <*> 0 . DP=31;I16=14,16,0,0,1066,38696,0,0,1769,105241,0,0,604,13924,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,218:8:0 0,15,147:5:0 +X 1453 . T <*> 0 . DP=31;I16=13,17,0,0,1107,42059,0,0,1769,105241,0,0,592,13444,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,199:7:0 0,15,165:5:0 +X 1454 . T <*> 0 . DP=31;I16=14,17,0,0,1139,42711,0,0,1829,108841,0,0,617,14045,0,0;QS=3,0;MQSB=0.962133;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,234:8:0 0,15,166:5:0 +X 1455 . G <*> 0 . DP=31;I16=13,17,0,0,1107,41765,0,0,1769,105241,0,0,592,13420,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,197:7:0 0,15,148:5:0 +X 1456 . T <*> 0 . DP=31;I16=14,17,0,0,1139,42717,0,0,1829,108841,0,0,617,14069,0,0;QS=3,0;MQSB=0.962133;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,215:8:0 0,15,170:5:0 +X 1457 . G <*> 0 . DP=31;I16=14,17,0,0,1129,42071,0,0,1829,108841,0,0,615,14019,0,0;QS=3,0;MQSB=0.962133;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,212:8:0 0,15,164:5:0 +X 1458 . T <*> 0 . DP=31;I16=14,17,0,0,1101,40243,0,0,1829,108841,0,0,613,13997,0,0;QS=3,0;MQSB=0.962133;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,220:8:0 0,15,165:5:0 +X 1459 . C A,<*> 0 . DP=31;I16=14,16,0,1,1164,45842,24,576,1769,105241,60,3600,608,13948,2,4;QS=2.87234,0.12766,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.962133;BQB=1;MQ0F=0 PL:DP:DV 0,54,255,54,255,255:18:0 0,24,224,24,224,224:8:0 9,0,135,21,138,152:5:1 +X 1460 . T <*> 0 . DP=32;I16=15,17,0,0,1243,48813,0,0,1889,112441,0,0,605,13833,0,0;QS=3,0;MQSB=0.960687;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,240:8:0 0,15,170:5:0 +X 1461 . G <*> 0 . DP=32;I16=15,17,0,0,1171,44033,0,0,1889,112441,0,0,600,13692,0,0;QS=3,0;MQSB=0.960687;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,224:8:0 0,15,157:5:0 +X 1462 . C <*> 0 . DP=30;I16=14,15,0,0,1102,42216,0,0,1709,101641,0,0,579,13241,0,0;QS=3,0;MQSB=0.954405;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,202:7:0 0,9,112:3:0 +X 1463 . T <*> 0 . DP=30;I16=15,15,0,0,1128,43348,0,0,1769,105241,0,0,592,13396,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,209:7:0 0,12,139:4:0 +X 1464 . G <*> 0 . DP=31;I16=14,16,0,0,1095,40557,0,0,1769,105241,0,0,563,12665,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,186:6:0 0,15,144:5:0 +X 1465 . T <*> 0 . DP=31;I16=15,16,0,0,1143,42557,0,0,1829,108841,0,0,584,13164,0,0;QS=3,0;MQSB=0.957006;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,204:7:0 0,15,166:5:0 +X 1466 . G <*> 0 . DP=31;I16=15,16,0,0,1122,42294,0,0,1829,108841,0,0,580,13018,0,0;QS=3,0;MQSB=0.957006;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,206:7:0 0,15,163:5:0 +X 1467 . A <*> 0 . DP=31;I16=14,16,0,0,1031,36341,0,0,1769,105241,0,0,569,12803,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,195:7:0 0,15,155:5:0 +X 1468 . A <*> 0 . DP=30;I16=15,15,0,0,991,34477,0,0,1769,105241,0,0,573,12717,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,177:7:0 0,15,158:5:0 +X 1469 . C T,<*> 0 . DP=31;I16=13,15,1,0,1013,37887,38,1444,1649,98041,60,3600,536,12106,9,81;QS=2.94025,0.0597484,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.954405;BQB=1;MQ0F=0 PL:DP:DV 0,16,255,51,255,255:18:1 0,18,178,18,178,178:6:0 0,15,160,15,160,160:5:0 +X 1470 . T <*> 0 . DP=31;I16=16,15,0,0,1110,41070,0,0,1829,108841,0,0,567,12489,0,0;QS=3,0;MQSB=0.951229;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,210:7:0 0,15,165:5:0 +X 1471 . G <*> 0 . DP=30;I16=16,14,0,0,1051,38425,0,0,1769,105241,0,0,564,12348,0,0;QS=3,0;MQSB=0.946202;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,192:7:0 0,12,128:4:0 +X 1472 . T <*> 0 . DP=30;I16=16,14,0,0,1049,38097,0,0,1769,105241,0,0,561,12237,0,0;QS=3,0;MQSB=0.946202;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,200:7:0 0,12,134:4:0 +X 1473 . C <*> 0 . DP=30;I16=16,14,0,0,1058,38526,0,0,1769,105241,0,0,558,12156,0,0;QS=3,0;MQSB=0.946202;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,175:7:0 0,12,140:4:0 +X 1474 . C <*> 0 . DP=30;I16=16,14,0,0,1120,42756,0,0,1769,105241,0,0,555,12105,0,0;QS=3,0;MQSB=0.946202;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,202:7:0 0,12,141:4:0 +X 1475 . T <*> 0 . DP=29;I16=14,14,0,0,1047,40395,0,0,1649,98041,0,0,537,11827,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,208:7:0 0,12,155:4:0 +X 1476 . T G,<*> 0 . DP=31;I16=15,15,1,0,1056,37884,14,196,1769,105241,60,3600,566,12614,10,100;QS=2.944,0.056,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.951229;BQB=1;MQ0F=0 PL:DP:DV 0,57,255,57,255,255:19:0 0,9,177,21,180,183:8:1 0,12,140,12,140,140:4:0 +X 1477 . G <*> 0 . DP=31;I16=16,15,0,0,1150,43390,0,0,1829,108841,0,0,574,12700,0,0;QS=3,0;MQSB=0.951229;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,217:8:0 0,12,138:4:0 +X 1478 . G <*> 0 . DP=31;I16=14,15,0,0,1008,36638,0,0,1709,101641,0,0,542,11982,0,0;QS=3,0;MQSB=0.954405;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,208:8:0 0,9,109:3:0 +X 1479 . C <*> 0 . DP=30;I16=15,15,0,0,1061,38671,0,0,1769,105241,0,0,564,12556,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,211:8:0 0,9,106:3:0 +X 1480 . C <*> 0 . DP=30;I16=15,15,0,0,1083,40355,0,0,1769,105241,0,0,561,12531,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,220:8:0 0,9,103:3:0 +X 1481 . T <*> 0 . DP=30;I16=15,15,0,0,1102,41308,0,0,1769,105241,0,0,558,12532,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,235:8:0 0,9,105:3:0 +X 1482 . G <*> 0 . DP=29;I16=15,14,0,0,1044,38550,0,0,1709,101641,0,0,556,12558,0,0;QS=3,0;MQSB=0.947838;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,210:8:0 0,6,75:2:0 +X 1483 . T <*> 0 . DP=31;I16=14,16,0,0,1042,37190,0,0,1769,105241,0,0,521,11919,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,215:7:0 0,9,100:3:0 +X 1484 . T <*> 0 . DP=31;I16=15,16,0,0,1067,37837,0,0,1829,108841,0,0,547,12587,0,0;QS=3,0;MQSB=0.957006;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,24,216:8:0 0,9,106:3:0 +X 1485 . T <*> 0 . DP=30;I16=15,15,0,0,1027,35863,0,0,1769,105241,0,0,549,12659,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,209:8:0 0,9,93:3:0 +X 1486 . G <*> 0 . DP=29;I16=15,14,0,0,1089,41679,0,0,1709,101641,0,0,551,12707,0,0;QS=3,0;MQSB=0.947838;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,198:7:0 0,9,108:3:0 +X 1487 . G <*> 0 . DP=28;I16=14,14,0,0,973,34723,0,0,1649,98041,0,0,554,12778,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,196:7:0 0,9,97:3:0 +X 1488 . T <*> 0 . DP=28;I16=13,14,0,0,928,32432,0,0,1589,94441,0,0,532,12246,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,176:6:0 0,9,102:3:0 +X 1489 . G <*> 0 . DP=27;I16=13,14,0,0,958,35292,0,0,1589,94441,0,0,535,12361,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,174:6:0 0,9,93:3:0 +X 1490 . A <*> 0 . DP=27;I16=13,14,0,0,928,33108,0,0,1589,94441,0,0,538,12446,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,160:5:0 0,9,94:3:0 +X 1491 . C <*> 0 . DP=27;I16=12,13,0,0,798,26812,0,0,1469,87241,0,0,499,11587,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,108:4:0 0,9,79:3:0 +X 1492 . G <*> 0 . DP=27;I16=13,14,0,0,893,30927,0,0,1589,94441,0,0,543,12527,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,136:5:0 0,9,100:3:0 +X 1493 . G <*> 0 . DP=27;I16=13,13,0,0,907,32761,0,0,1529,90841,0,0,520,11948,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,155:5:0 0,9,106:3:0 +X 1494 . G <*> 0 . DP=27;I16=13,14,0,0,939,33599,0,0,1589,94441,0,0,547,12639,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,156:5:0 0,9,107:3:0 +X 1495 . T <*> 0 . DP=26;I16=12,13,0,0,814,27700,0,0,1469,87241,0,0,524,12048,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,143:5:0 0,9,105:3:0 +X 1496 . G <*> 0 . DP=26;I16=13,13,0,0,969,36751,0,0,1529,90841,0,0,550,12674,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,157:5:0 0,9,107:3:0 +X 1497 . A <*> 0 . DP=27;I16=12,14,0,0,904,32740,0,0,1529,90841,0,0,525,12019,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,166:5:0 0,9,113:3:0 +X 1498 . G <*> 0 . DP=27;I16=13,14,0,0,1002,37852,0,0,1589,94441,0,0,551,12635,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,153:5:0 0,9,112:3:0 +X 1499 . G <*> 0 . DP=28;I16=14,14,0,0,973,34891,0,0,1649,98041,0,0,551,12599,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,146:5:0 0,9,108:3:0 +X 1500 . A <*> 0 . DP=28;I16=14,14,0,0,1023,38115,0,0,1649,98041,0,0,552,12588,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,165:5:0 0,9,115:3:0 +X 1501 . G <*> 0 . DP=28;I16=14,14,0,0,1051,40105,0,0,1649,98041,0,0,551,12505,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,163:5:0 0,9,100:3:0 +X 1502 . C <*> 0 . DP=27;I16=13,14,0,0,963,35241,0,0,1589,94441,0,0,549,12351,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,140:5:0 0,9,105:3:0 +X 1503 . A <*> 0 . DP=28;I16=14,14,0,0,1026,38252,0,0,1649,98041,0,0,546,12176,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,171:5:0 0,9,109:3:0 +X 1504 . G <*> 0 . DP=28;I16=13,14,0,0,1052,41226,0,0,1589,94441,0,0,523,11591,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,163:5:0 0,9,111:3:0 +X 1505 . G <*> 0 . DP=28;I16=14,13,0,0,959,35545,0,0,1589,94441,0,0,517,11295,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,155:5:0 0,9,114:3:0 +X 1506 . G <*> 0 . DP=28;I16=14,14,0,0,1013,37355,0,0,1649,98041,0,0,540,11840,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,139:5:0 0,9,112:3:0 +X 1507 . A <*> 0 . DP=28;I16=14,14,0,0,987,35217,0,0,1649,98041,0,0,538,11792,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,162:5:0 0,9,114:3:0 +X 1508 . C <*> 0 . DP=28;I16=14,14,0,0,1033,38663,0,0,1649,98041,0,0,535,11727,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,137:5:0 0,9,112:3:0 +X 1509 . A <*> 0 . DP=28;I16=15,13,0,0,1028,38610,0,0,1649,98041,0,0,529,11493,0,0;QS=3,0;MQSB=0.942064;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,12,128:4:0 0,9,122:3:0 +X 1510 . G <*> 0 . DP=28;I16=15,13,0,0,1064,40824,0,0,1649,98041,0,0,524,11288,0,0;QS=3,0;MQSB=0.942064;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,12,132:4:0 0,9,111:3:0 +X 1511 . A <*> 0 . DP=28;I16=15,13,0,0,976,34794,0,0,1649,98041,0,0,519,11113,0,0;QS=3,0;MQSB=0.942064;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,12,136:4:0 0,9,110:3:0 +X 1512 . A <*> 0 . DP=28;I16=15,12,0,0,998,37460,0,0,1589,94441,0,0,489,10343,0,0;QS=3,0;MQSB=0.935229;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,142:4:0 0,9,110:3:0 +X 1513 . G <*> 0 . DP=28;I16=14,13,0,0,1014,38940,0,0,1589,94441,0,0,497,10709,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,134:4:0 0,9,108:3:0 +X 1514 . G <*> 0 . DP=28;I16=15,13,0,0,1054,39954,0,0,1649,98041,0,0,504,10768,0,0;QS=3,0;MQSB=0.942064;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,12,134:4:0 0,9,108:3:0 +X 1515 . G <*> 0 . DP=28;I16=14,13,0,0,948,34152,0,0,1589,94441,0,0,488,10564,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,133:4:0 0,9,101:3:0 +X 1516 . T <*> 0 . DP=27;I16=12,13,0,0,811,27385,0,0,1469,87241,0,0,472,10338,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,117:4:0 0,9,106:3:0 +X 1517 . C <*> 0 . DP=27;I16=13,13,0,0,943,35153,0,0,1529,90841,0,0,478,10380,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,12,134:4:0 0,9,97:3:0 +X 1518 . C <*> 0 . DP=28;I16=13,12,0,0,908,33852,0,0,1469,87241,0,0,427,9261,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,132:4:0 0,9,96:3:0 +X 1519 . T <*> 0 . DP=28;I16=15,13,0,0,988,35808,0,0,1649,98041,0,0,475,10337,0,0;QS=3,0;MQSB=0.942064;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,154:5:0 0,9,110:3:0 +X 1520 . G <*> 0 . DP=29;I16=16,13,0,0,1005,36307,0,0,1709,101641,0,0,470,10328,0,0;QS=3,0;MQSB=0.940317;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,18,150:6:0 0,9,104:3:0 +X 1521 . C <*> 0 . DP=28;I16=16,12,0,0,900,30324,0,0,1649,98041,0,0,466,10300,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,164:6:0 0,9,88:3:0 +X 1522 . G <*> 0 . DP=27;I16=15,10,0,0,784,25144,0,0,1469,87241,0,0,442,9956,0,0;QS=3,0;MQSB=0.9171;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,110:5:0 0,9,91:3:0 +X 1523 . T <*> 0 . DP=27;I16=16,11,0,0,921,32001,0,0,1589,94441,0,0,457,10189,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,136:5:0 0,9,108:3:0 +X 1524 . G <*> 0 . DP=27;I16=16,10,0,0,932,34140,0,0,1529,90841,0,0,453,10153,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,12,108:4:0 0,9,103:3:0 +X 1525 . C <*> 0 . DP=27;I16=16,11,0,0,972,35704,0,0,1589,94441,0,0,473,10719,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,113:4:0 0,9,112:3:0 +X 1526 . C <*> 0 . DP=25;I16=14,11,0,0,883,31843,0,0,1469,87241,0,0,470,10684,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,109:4:0 0,9,106:3:0 +X 1527 . C <*> 0 . DP=24;I16=14,10,0,0,867,31999,0,0,1440,86400,0,0,466,10572,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,107:4:0 0,9,112:3:0 +X 1528 . T <*> 0 . DP=23;I16=13,10,0,0,869,33133,0,0,1380,82800,0,0,463,10483,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,114:4:0 0,9,113:3:0 +X 1529 . G <*> 0 . DP=23;I16=13,10,0,0,812,29432,0,0,1380,82800,0,0,459,10365,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,108:4:0 0,9,104:3:0 +X 1530 . C <*> 0 . DP=24;I16=13,10,0,0,819,30073,0,0,1380,82800,0,0,446,10186,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,137:5:0 0,9,106:3:0 +X 1531 . C <*> 0 . DP=24;I16=13,11,0,0,877,32969,0,0,1440,86400,0,0,452,10190,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,144:5:0 0,9,105:3:0 +X 1532 . T <*> 0 . DP=24;I16=13,11,0,0,887,33721,0,0,1440,86400,0,0,449,10135,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,165:5:0 0,9,120:3:0 +X 1533 . T <*> 0 . DP=23;I16=13,10,0,0,793,27987,0,0,1380,82800,0,0,447,10101,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,146:5:0 0,9,107:3:0 +X 1534 . C <*> 0 . DP=23;I16=14,9,0,0,847,31627,0,0,1380,82800,0,0,446,10086,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,153:5:0 0,9,109:3:0 +X 1535 . A <*> 0 . DP=23;I16=14,9,0,0,770,26604,0,0,1380,82800,0,0,444,9990,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,144:5:0 0,9,99:3:0 +X 1536 . C <*> 0 . DP=24;I16=15,9,0,0,826,28984,0,0,1440,86400,0,0,442,9914,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,138:5:0 0,9,110:3:0 +X 1537 . A <*> 0 . DP=24;I16=14,9,0,0,844,31384,0,0,1380,82800,0,0,416,9234,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,149:5:0 0,9,115:3:0 +X 1538 . A <*> 0 . DP=24;I16=15,9,0,0,909,34727,0,0,1440,86400,0,0,440,9826,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,154:5:0 0,9,112:3:0 +X 1539 . G <*> 0 . DP=24;I16=15,9,0,0,913,35327,0,0,1440,86400,0,0,439,9815,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,149:5:0 0,9,117:3:0 +X 1540 . C <*> 0 . DP=23;I16=15,8,0,0,828,30260,0,0,1380,82800,0,0,438,9776,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,146:5:0 0,9,102:3:0 +X 1541 . C <*> 0 . DP=23;I16=15,8,0,0,823,30615,0,0,1380,82800,0,0,437,9759,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,142:5:0 0,9,108:3:0 +X 1542 . C <*> 0 . DP=25;I16=16,8,0,0,893,33843,0,0,1440,86400,0,0,435,9715,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,147:5:0 0,12,131:4:0 +X 1543 . C <*> 0 . DP=25;I16=16,8,0,0,880,33206,0,0,1440,86400,0,0,434,9696,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,141:5:0 0,12,136:4:0 +X 1544 . T <*> 0 . DP=25;I16=16,8,0,0,899,34405,0,0,1440,86400,0,0,431,9603,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,150:5:0 0,12,148:4:0 +X 1545 . G <*> 0 . DP=25;I16=16,8,0,0,874,32636,0,0,1440,86400,0,0,428,9536,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,146:5:0 0,12,129:4:0 +X 1546 . G <*> 0 . DP=24;I16=15,8,0,0,796,28796,0,0,1380,82800,0,0,425,9443,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,130:5:0 0,9,110:3:0 +X 1547 . A <*> 0 . DP=23;I16=15,8,0,0,837,30945,0,0,1380,82800,0,0,448,9996,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,176:6:0 0,9,112:3:0 +X 1548 . A <*> 0 . DP=23;I16=14,8,0,0,812,30830,0,0,1320,79200,0,0,421,9319,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,173:5:0 0,9,115:3:0 +X 1549 . G <*> 0 . DP=23;I16=15,8,0,0,870,33642,0,0,1380,82800,0,0,444,9912,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,174:6:0 0,9,114:3:0 +X 1550 . G <*> 0 . DP=23;I16=15,8,0,0,790,28502,0,0,1380,82800,0,0,442,9900,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,154:6:0 0,9,109:3:0 +X 1551 . A <*> 0 . DP=23;I16=15,8,0,0,802,28596,0,0,1380,82800,0,0,440,9908,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,173:6:0 0,9,107:3:0 +X 1552 . A <*> 0 . DP=21;I16=14,7,0,0,792,30156,0,0,1260,75600,0,0,438,9836,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,196:6:0 0,9,110:3:0 +X 1553 . A <*> 0 . DP=21;I16=13,7,0,0,738,28112,0,0,1200,72000,0,0,411,9159,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,251:11:0 0,18,192:6:0 0,9,115:3:0 +X 1554 . G <*> 0 . DP=21;I16=14,7,0,0,763,28221,0,0,1260,75600,0,0,434,9752,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,171:6:0 0,9,101:3:0 +X 1555 . T <*> 0 . DP=21;I16=14,7,0,0,726,26234,0,0,1260,75600,0,0,432,9740,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,252:12:0 0,18,169:6:0 0,9,108:3:0 +X 1556 . T <*> 0 . DP=21;I16=14,7,0,0,745,26971,0,0,1260,75600,0,0,429,9697,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,253:12:0 0,18,177:6:0 0,9,110:3:0 +X 1557 . G <*> 0 . DP=22;I16=15,7,0,0,801,29689,0,0,1320,79200,0,0,426,9672,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,166:6:0 0,9,101:3:0 +X 1558 . T <*> 0 . DP=22;I16=15,6,0,0,720,25620,0,0,1260,75600,0,0,404,9244,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,131:5:0 0,9,112:3:0 +X 1559 . T <*> 0 . DP=22;I16=15,7,0,0,712,24690,0,0,1320,79200,0,0,417,9439,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,248:13:0 0,18,158:6:0 0,9,103:3:0 +X 1560 . T <*> 0 . DP=21;I16=14,7,0,0,736,26560,0,0,1260,75600,0,0,412,9284,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,251:12:0 0,18,170:6:0 0,9,112:3:0 +X 1561 . T <*> 0 . DP=21;I16=14,7,0,0,706,24776,0,0,1260,75600,0,0,406,9102,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,241:12:0 0,18,174:6:0 0,9,106:3:0 +X 1562 . G <*> 0 . DP=21;I16=14,7,0,0,765,28655,0,0,1260,75600,0,0,399,8893,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,181:6:0 0,9,108:3:0 +X 1563 . G <*> 0 . DP=22;I16=13,7,0,0,713,26255,0,0,1200,72000,0,0,360,8176,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,147:5:0 0,9,108:3:0 +X 1564 . G <*> 0 . DP=22;I16=13,8,0,0,721,25457,0,0,1260,75600,0,0,368,8218,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,173:6:0 0,9,95:3:0 +X 1565 . A <*> 0 . DP=21;I16=14,7,0,0,724,25888,0,0,1260,75600,0,0,380,8352,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,162:6:0 0,6,71:2:0 +X 1566 . T <*> 0 . DP=21;I16=13,7,0,0,698,25286,0,0,1200,72000,0,0,364,8086,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,143:5:0 0,6,78:2:0 +X 1567 . C <*> 0 . DP=20;I16=12,6,0,0,652,24422,0,0,1080,64800,0,0,351,7881,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,104:3:0 0,6,72:2:0 +X 1568 . T <*> 0 . DP=20;I16=13,7,0,0,711,26125,0,0,1200,72000,0,0,363,7871,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,157:5:0 0,6,74:2:0 +X 1569 . C <*> 0 . DP=19;I16=12,6,0,0,676,25850,0,0,1080,64800,0,0,351,7669,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,128:4:0 0,6,76:2:0 +X 1570 . T <*> 0 . DP=19;I16=12,7,0,0,700,26750,0,0,1140,68400,0,0,353,7583,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,149:5:0 0,6,71:2:0 +X 1571 . G <*> 0 . DP=19;I16=12,6,0,0,639,23361,0,0,1080,64800,0,0,343,7441,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,125:4:0 0,6,70:2:0 +X 1572 . C <*> 0 . DP=19;I16=11,6,0,0,640,24568,0,0,1020,61200,0,0,328,7202,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,125:4:0 0,6,70:2:0 +X 1573 . A <*> 0 . DP=19;I16=11,4,0,0,565,21475,0,0,900,54000,0,0,304,6900,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,132:4:0 0,3,40:1:0 +X 1574 . C <*> 0 . DP=19;I16=12,5,0,0,636,24076,0,0,1020,61200,0,0,318,6948,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,128:4:0 0,3,38:1:0 +X 1575 . C <*> 0 . DP=19;I16=11,6,0,0,610,22742,0,0,1020,61200,0,0,296,6272,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,125:4:0 0,6,71:2:0 +X 1576 . C <*> 0 . DP=19;I16=12,6,0,0,675,25821,0,0,1080,64800,0,0,315,6785,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,133:4:0 0,6,78:2:0 +X 1577 . T <*> 0 . DP=17;I16=11,6,0,0,650,25330,0,0,1020,61200,0,0,310,6692,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,118:3:0 0,6,77:2:0 +X 1578 . C <*> 0 . DP=17;I16=10,6,0,0,622,24364,0,0,960,57600,0,0,279,5943,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,84:2:0 0,6,77:2:0 +X 1579 . A <*> 0 . DP=17;I16=11,6,0,0,596,22326,0,0,1020,61200,0,0,298,6464,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,116:3:0 0,6,80:2:0 +X 1580 . G <*> 0 . DP=17;I16=11,6,0,0,651,25195,0,0,1020,61200,0,0,292,6380,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,109:3:0 0,6,77:2:0 +X 1581 . C <*> 0 . DP=17;I16=11,6,0,0,586,21418,0,0,1020,61200,0,0,286,6316,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,103:3:0 0,6,71:2:0 +X 1582 . C <*> 0 . DP=18;I16=11,7,0,0,639,23491,0,0,1080,64800,0,0,280,6272,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,109:3:0 0,6,75:2:0 +X 1583 . T <*> 0 . DP=16;I16=10,6,0,0,591,22349,0,0,960,57600,0,0,276,6196,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,112:3:0 0,6,74:2:0 +X 1584 . G <*> 0 . DP=15;I16=10,5,0,0,563,21283,0,0,900,54000,0,0,272,6086,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,105:3:0 0,3,39:1:0 +X 1585 . G <*> 0 . DP=16;I16=10,5,0,0,494,17160,0,0,900,54000,0,0,251,5703,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,244:11:0 0,9,103:3:0 0,3,30:1:0 +X 1586 . A <*> 0 . DP=15;I16=10,3,0,0,470,17200,0,0,780,46800,0,0,237,5273,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,223:10:0 0,6,79:2:0 0,3,42:1:0 +X 1587 . C <*> 0 . DP=15;I16=11,4,0,0,508,17900,0,0,900,54000,0,0,264,5852,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,247:11:0 0,9,94:3:0 0,3,31:1:0 +X 1588 . A <*> 0 . DP=15;I16=11,4,0,0,511,17939,0,0,900,54000,0,0,262,5806,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,232:11:0 0,9,105:3:0 0,3,41:1:0 +X 1589 . A <*> 0 . DP=15;I16=11,4,0,0,536,19584,0,0,900,54000,0,0,259,5725,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,249:11:0 0,9,106:3:0 0,3,42:1:0 +X 1590 . C <*> 0 . DP=15;I16=10,5,0,0,514,18228,0,0,900,54000,0,0,257,5657,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,231:10:0 0,9,104:3:0 0,6,71:2:0 +X 1591 . T <*> 0 . DP=15;I16=10,5,0,0,515,18559,0,0,900,54000,0,0,256,5602,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,241:10:0 0,9,85:3:0 0,6,73:2:0 +X 1592 . T <*> 0 . DP=15;I16=10,5,0,0,503,17345,0,0,900,54000,0,0,255,5561,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,225:10:0 0,9,107:3:0 0,6,62:2:0 +X 1593 . G <*> 0 . DP=15;I16=10,5,0,0,540,19930,0,0,900,54000,0,0,254,5534,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,9,106:3:0 0,6,60:2:0 +X 1594 . T <*> 0 . DP=15;I16=10,5,0,0,535,19445,0,0,900,54000,0,0,252,5472,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,234:10:0 0,9,106:3:0 0,6,80:2:0 +X 1595 . G <*> 0 . DP=15;I16=10,4,0,0,494,17940,0,0,840,50400,0,0,225,4801,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,213:9:0 0,9,105:3:0 0,6,69:2:0 +X 1596 . C <*> 0 . DP=15;I16=10,4,0,0,479,17011,0,0,840,50400,0,0,233,5151,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,200:9:0 0,9,111:3:0 0,6,74:2:0 +X 1597 . C <*> 0 . DP=15;I16=10,5,0,0,489,16941,0,0,900,54000,0,0,245,5285,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,195:9:0 0,12,127:4:0 0,6,73:2:0 +X 1598 . C <*> 0 . DP=15;I16=10,5,0,0,514,18282,0,0,900,54000,0,0,244,5240,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,207:9:0 0,12,133:4:0 0,6,68:2:0 +X 1599 . A <*> 0 . DP=14;I16=8,5,0,0,436,15330,0,0,780,46800,0,0,225,4851,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,182:8:0 0,9,103:3:0 0,6,76:2:0 +X 1600 . T <*> 0 . DP=13;I16=8,5,0,0,456,16430,0,0,780,46800,0,0,226,4876,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,193:8:0 0,9,105:3:0 0,6,79:2:0 +X 1601 . C <*> 0 . DP=13;I16=8,4,0,0,431,15861,0,0,720,43200,0,0,208,4554,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,171:7:0 0,9,108:3:0 0,6,78:2:0 +X 1602 . T <*> 0 . DP=13;I16=7,5,0,0,439,16867,0,0,720,43200,0,0,228,4968,0,0;QS=3,0;MQSB=0.95494;MQ0F=0 PL:DP:DV 0,21,179:7:0 0,9,115:3:0 0,6,85:2:0 +X 1603 . G <*> 0 . DP=12;I16=7,5,0,0,455,17407,0,0,720,43200,0,0,230,5034,0,0;QS=3,0;MQSB=0.95494;MQ0F=0 PL:DP:DV 0,21,202:7:0 0,9,111:3:0 0,6,75:2:0 +X 1604 . G <*> 0 . DP=12;I16=7,5,0,0,362,11620,0,0,720,43200,0,0,232,5112,0,0;QS=3,0;MQSB=0.95494;MQ0F=0 PL:DP:DV 0,21,163:7:0 0,9,84:3:0 0,6,66:2:0 +X 1605 . T <*> 0 . DP=12;I16=7,5,0,0,410,14230,0,0,720,43200,0,0,234,5202,0,0;QS=3,0;MQSB=0.95494;MQ0F=0 PL:DP:DV 0,21,190:7:0 0,9,97:3:0 0,6,61:2:0 +X 1606 . G <*> 0 . DP=12;I16=7,4,0,0,370,12738,0,0,660,39600,0,0,211,4679,0,0;QS=3,0;MQSB=0.964642;MQ0F=0 PL:DP:DV 0,18,165:6:0 0,9,91:3:0 0,6,56:2:0 +X 1607 . A <*> 0 . DP=12;I16=7,4,0,0,337,11369,0,0,660,39600,0,0,226,5222,0,0;QS=3,0;MQSB=0.964642;MQ0F=0 PL:DP:DV 0,21,161:7:0 0,6,70:2:0 0,6,55:2:0 +X 1608 . C <*> 0 . DP=12;I16=7,4,0,0,366,12898,0,0,660,39600,0,0,211,4727,0,0;QS=3,0;MQSB=0.964642;MQ0F=0 PL:DP:DV 0,18,141:6:0 0,9,111:3:0 0,6,62:2:0 +X 1609 . C <*> 0 . DP=11;I16=6,5,0,0,365,12889,0,0,660,39600,0,0,237,5393,0,0;QS=3,0;MQSB=0.950952;MQ0F=0 PL:DP:DV 0,18,149:6:0 0,9,110:3:0 0,6,71:2:0 +X 1610 . C <*> 0 . DP=11;I16=5,5,0,0,313,10713,0,0,600,36000,0,0,213,4819,0,0;QS=3,0;MQSB=0.952347;MQ0F=0 PL:DP:DV 0,15,127:5:0 0,9,106:3:0 0,6,57:2:0 +X 1611 . C <*> 0 . DP=11;I16=6,5,0,0,398,14904,0,0,660,39600,0,0,238,5454,0,0;QS=3,0;MQSB=0.950952;MQ0F=0 PL:DP:DV 0,18,180:6:0 0,9,110:3:0 0,6,67:2:0 +X 1612 . T <*> 0 . DP=11;I16=6,5,0,0,409,15421,0,0,660,39600,0,0,238,5472,0,0;QS=3,0;MQSB=0.950952;MQ0F=0 PL:DP:DV 0,18,174:6:0 0,9,107:3:0 0,6,83:2:0 +X 1613 . C <*> 0 . DP=11;I16=6,5,0,0,372,12904,0,0,660,39600,0,0,238,5498,0,0;QS=3,0;MQSB=0.950952;MQ0F=0 PL:DP:DV 0,18,169:6:0 0,9,99:3:0 0,6,63:2:0 +X 1614 . A <*> 0 . DP=11;I16=6,5,0,0,353,12139,0,0,660,39600,0,0,238,5532,0,0;QS=3,0;MQSB=0.950952;MQ0F=0 PL:DP:DV 0,18,147:6:0 0,9,98:3:0 0,6,69:2:0 +X 1615 . C <*> 0 . DP=11;I16=6,5,0,0,366,13080,0,0,660,39600,0,0,238,5574,0,0;QS=3,0;MQSB=0.950952;MQ0F=0 PL:DP:DV 0,18,171:6:0 0,9,105:3:0 0,6,51:2:0 +X 1616 . T <*> 0 . DP=11;I16=6,3,0,0,348,13606,0,0,540,32400,0,0,187,4323,0,0;QS=3,0;MQSB=0.924584;MQ0F=0 PL:DP:DV 0,15,159:5:0 0,9,105:3:0 0,3,42:1:0 +X 1617 . C <*> 0 . DP=12;I16=6,3,0,0,330,12316,0,0,540,32400,0,0,185,4279,0,0;QS=3,0;MQSB=0.924584;MQ0F=0 PL:DP:DV 0,15,146:5:0 0,9,105:3:0 0,3,42:1:0 +X 1618 . A <*> 0 . DP=12;I16=5,6,0,0,385,14199,0,0,629,36841,0,0,244,5636,0,0;QS=3,0;MQSB=0.891517;MQ0F=0 PL:DP:DV 0,18,151:6:0 0,9,93:3:0 0,6,81:2:0 +X 1619 . G <*> 0 . DP=11;I16=5,6,0,0,377,13119,0,0,629,36841,0,0,242,5544,0,0;QS=3,0;MQSB=0.891517;MQ0F=0 PL:DP:DV 0,18,166:6:0 0,9,84:3:0 0,6,67:2:0 +X 1620 . C <*> 0 . DP=11;I16=5,5,0,0,323,10965,0,0,569,33241,0,0,215,4839,0,0;QS=3,0;MQSB=0.857112;MQ0F=0 PL:DP:DV 0,15,142:5:0 0,9,78:3:0 0,6,56:2:0 +X 1621 . C <*> 0 . DP=12;I16=5,7,0,0,363,11779,0,0,689,40441,0,0,263,6021,0,0;QS=3,0;MQSB=0.896474;MQ0F=0 PL:DP:DV 0,21,174:7:0 0,9,80:3:0 0,6,56:2:0 +X 1622 . A <*> 0 . DP=12;I16=5,7,0,0,365,12105,0,0,689,40441,0,0,261,5965,0,0;QS=3,0;MQSB=0.896474;MQ0F=0 PL:DP:DV 0,21,176:7:0 0,9,81:3:0 0,6,52:2:0 +X 1623 . C <*> 0 . DP=12;I16=5,5,0,0,325,10979,0,0,569,33241,0,0,208,4620,0,0;QS=3,0;MQSB=0.857112;MQ0F=0 PL:DP:DV 0,18,155:6:0 0,9,84:3:0 0,3,37:1:0 +X 1624 . C <*> 0 . DP=12;I16=4,6,0,0,336,11718,0,0,569,33241,0,0,211,4799,0,0;QS=3,0;MQSB=0.895781;MQ0F=0 PL:DP:DV 0,18,162:6:0 0,9,88:3:0 0,3,39:1:0 +X 1625 . A <*> 0 . DP=12;I16=4,7,0,0,375,13503,0,0,629,36841,0,0,234,5386,0,0;QS=3,0;MQSB=0.924449;MQ0F=0 PL:DP:DV 0,18,158:6:0 0,9,93:3:0 0,6,80:2:0 +X 1626 . G <*> 0 . DP=12;I16=5,7,0,0,358,11490,0,0,689,40441,0,0,249,5645,0,0;QS=3,0;MQSB=0.896474;MQ0F=0 PL:DP:DV 0,21,158:7:0 0,9,83:3:0 0,6,63:2:0 +X 1627 . A <*> 0 . DP=12;I16=5,7,0,0,363,11609,0,0,689,40441,0,0,246,5590,0,0;QS=3,0;MQSB=0.896474;MQ0F=0 PL:DP:DV 0,21,165:7:0 0,9,75:3:0 0,6,72:2:0 +X 1628 . C <*> 0 . DP=12;I16=5,7,0,0,357,11583,0,0,689,40441,0,0,243,5545,0,0;QS=3,0;MQSB=0.896474;MQ0F=0 PL:DP:DV 0,21,165:7:0 0,9,80:3:0 0,6,57:2:0 +X 1629 . T <*> 0 . DP=13;I16=6,7,0,0,451,16079,0,0,749,44041,0,0,240,5510,0,0;QS=3,0;MQSB=0.899815;MQ0F=0 PL:DP:DV 0,21,187:7:0 0,12,120:4:0 0,6,79:2:0 +X 1630 . T <*> 0 . DP=13;I16=6,7,0,0,403,13323,0,0,749,44041,0,0,237,5435,0,0;QS=3,0;MQSB=0.899815;MQ0F=0 PL:DP:DV 0,21,169:7:0 0,12,111:4:0 0,6,73:2:0 +X 1631 . C <*> 0 . DP=12;I16=6,5,0,0,354,12046,0,0,660,39600,0,0,210,4744,0,0;QS=3,0;MQSB=0.950952;MQ0F=0 PL:DP:DV 0,21,184:7:0 0,6,67:2:0 0,6,61:2:0 +X 1632 . C <*> 0 . DP=13;I16=6,7,0,0,387,12175,0,0,749,44041,0,0,232,5262,0,0;QS=3,0;MQSB=0.899815;MQ0F=0 PL:DP:DV 0,24,188:8:0 0,9,82:3:0 0,6,61:2:0 +X 1633 . A <*> 0 . DP=13;I16=6,7,0,0,404,13272,0,0,749,44041,0,0,230,5166,0,0;QS=3,0;MQSB=0.899815;MQ0F=0 PL:DP:DV 0,24,183:8:0 0,9,86:3:0 0,6,73:2:0 +X 1634 . C <*> 0 . DP=13;I16=6,6,0,0,328,9716,0,0,689,40441,0,0,203,4457,0,0;QS=3,0;MQSB=0.864013;MQ0F=0 PL:DP:DV 0,21,151:7:0 0,9,80:3:0 0,6,59:2:0 +X 1635 . G <*> 0 . DP=14;I16=6,8,0,0,419,12831,0,0,809,47641,0,0,226,5010,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,24,180:8:0 0,12,108:4:0 0,6,59:2:0 +X 1636 . A <*> 0 . DP=14;I16=6,8,0,0,418,13400,0,0,809,47641,0,0,225,4951,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,24,179:8:0 0,12,110:4:0 0,6,66:2:0 +X 1637 . C <*> 0 . DP=14;I16=6,8,0,0,422,13498,0,0,809,47641,0,0,224,4906,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,24,185:8:0 0,12,110:4:0 0,6,60:2:0 +X 1638 . A <*> 0 . DP=17;I16=9,7,0,0,513,17167,0,0,929,54841,0,0,216,4790,0,0;QS=3,0;MQSB=0.892753;MQ0F=0 PL:DP:DV 0,24,191:8:0 0,18,149:6:0 0,6,78:2:0 +X 1639 . G <*> 0 . DP=17;I16=9,8,0,0,552,18844,0,0,989,58441,0,0,223,4765,0,0;QS=3,0;MQSB=0.91051;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,18,150:6:0 0,6,68:2:0 +X 1640 . G <*> 0 . DP=17;I16=8,6,0,0,414,13296,0,0,809,47641,0,0,171,3467,0,0;QS=3,0;MQSB=0.875173;MQ0F=0 PL:DP:DV 0,18,150:6:0 0,18,151:6:0 0,6,51:2:0 +X 1641 . C <*> 0 . DP=18;I16=9,8,0,0,511,16289,0,0,989,58441,0,0,225,4709,0,0;QS=3,0;MQSB=0.91051;MQ0F=0 PL:DP:DV 0,27,188:9:0 0,18,167:6:0 0,6,65:2:0 +X 1642 . T <*> 0 . DP=17;I16=8,7,0,0,519,18513,0,0,869,51241,0,0,217,4613,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,18,170:6:0 0,18,168:6:0 0,9,102:3:0 +X 1643 . C <*> 0 . DP=16;I16=7,9,0,0,508,16910,0,0,929,54841,0,0,255,5361,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,24,193:8:0 0,18,169:6:0 0,6,56:2:0 +X 1644 . C <*> 0 . DP=15;I16=6,9,0,0,514,18056,0,0,869,51241,0,0,259,5401,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,21,209:7:0 0,18,165:6:0 0,6,54:2:0 +X 1645 . A <*> 0 . DP=15;I16=6,9,0,0,520,18852,0,0,869,51241,0,0,263,5457,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,21,213:7:0 0,18,173:6:0 0,6,49:2:0 +X 1646 . G <*> 0 . DP=15;I16=6,7,0,0,440,15526,0,0,780,46800,0,0,217,4279,0,0;QS=3,0;MQSB=0.961166;MQ0F=0 PL:DP:DV 0,18,185:6:0 0,15,148:5:0 0,6,48:2:0 +X 1647 . C <*> 0 . DP=15;I16=6,9,0,0,433,13883,0,0,869,51241,0,0,271,5617,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,21,190:7:0 0,18,139:6:0 0,6,35:2:0 +X 1648 . C <*> 0 . DP=15;I16=6,9,0,0,495,16965,0,0,869,51241,0,0,275,5721,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,21,203:7:0 0,18,159:6:0 0,6,44:2:0 +X 1649 . T <*> 0 . DP=15;I16=6,9,0,0,516,18122,0,0,869,51241,0,0,279,5841,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,21,187:7:0 0,18,182:6:0 0,6,56:2:0 +X 1650 . C <*> 0 . DP=15;I16=6,7,0,0,405,13551,0,0,749,44041,0,0,240,5028,0,0;QS=3,0;MQSB=0.899815;MQ0F=0 PL:DP:DV 0,18,161:6:0 0,18,169:6:0 0,3,13:1:0 +X 1651 . G <*> 0 . DP=17;I16=5,9,0,0,424,13328,0,0,778,44882,0,0,249,5335,0,0;QS=3,0;MQSB=0.965069;MQ0F=0 PL:DP:DV 0,18,150:6:0 0,15,128:5:0 0,9,86:3:0 +X 1652 . G <*> 0 . DP=18;I16=7,9,0,0,532,18602,0,0,898,52082,0,0,267,5673,0,0;QS=3,0;MQSB=0.994413;MQ0F=0 PL:DP:DV 0,24,212:8:0 0,18,168:6:0 0,6,54:2:0 +X 1653 . C <*> 0 . DP=18;I16=8,10,0,0,581,19565,0,0,1018,59282,0,0,300,6490,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,24,208:8:0 0,21,175:7:0 0,9,82:3:0 +X 1654 . A T,<*> 0 . DP=18;I16=8,9,0,1,516,16718,15,225,958,55682,60,3600,285,6219,22,484;QS=2.93213,0.0678733,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.99606;BQB=1;MQ0F=0 PL:DP:DV 0,9,155,21,158,162:8:1 0,21,179,21,179,179:7:0 0,9,78,9,78,78:3:0 +X 1655 . C <*> 0 . DP=18;I16=8,10,0,0,565,19017,0,0,1018,59282,0,0,313,6887,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,24,198:8:0 0,21,180:7:0 0,9,79:3:0 +X 1656 . C <*> 0 . DP=19;I16=9,9,0,0,557,18013,0,0,1018,59282,0,0,295,6515,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,202:8:0 0,21,165:7:0 0,9,80:3:0 +X 1657 . T A,<*> 0 . DP=18;I16=8,9,0,1,580,20362,15,225,989,58441,29,841,301,6641,25,625;QS=2.93243,0.0675676,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.99606;BQB=1;MQ0F=0 PL:DP:DV 0,24,206,24,206,206:8:0 0,6,158,18,161,165:7:1 0,9,85,9,85,85:3:0 +X 1658 . T <*> 0 . DP=19;I16=8,10,0,0,573,19127,0,0,1018,59282,0,0,332,7412,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,24,187:8:0 0,21,189:7:0 0,9,91:3:0 +X 1659 . C <*> 0 . DP=20;I16=8,10,0,0,609,21517,0,0,1049,62041,0,0,338,7578,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,24,219:8:0 0,21,189:7:0 0,9,80:3:0 +X 1660 . A <*> 0 . DP=21;I16=8,11,0,0,641,23219,0,0,1078,62882,0,0,385,8901,0,0;QS=3,0;MQSB=0.992359;MQ0F=0 PL:DP:DV 0,21,172:7:0 0,24,219:8:0 0,12,127:4:0 +X 1661 . G <*> 0 . DP=21;I16=7,13,0,0,639,21739,0,0,1107,63723,0,0,412,9598,0,0;QS=3,0;MQSB=0.999215;MQ0F=0 PL:DP:DV 0,24,209:8:0 0,24,193:8:0 0,12,98:4:0 +X 1662 . C <*> 0 . DP=21;I16=8,12,0,0,641,21423,0,0,1107,63723,0,0,407,9465,0,0;QS=3,0;MQSB=0.988166;MQ0F=0 PL:DP:DV 0,21,192:7:0 0,27,211:9:0 0,12,100:4:0 +X 1663 . C <*> 0 . DP=20;I16=7,11,0,0,577,19507,0,0,1018,59282,0,0,394,9204,0,0;QS=3,0;MQSB=0.983729;MQ0F=0 PL:DP:DV 0,21,178:7:0 0,21,192:7:0 0,12,101:4:0 +X 1664 . A C,<*> 0 . DP=20;I16=6,10,0,1,530,17982,13,169,898,52082,29,841,358,8422,25,625;QS=2.93953,0.0604651,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.998738;BQB=1;MQ0F=0 PL:DP:DV 0,18,167,18,167,167:6:0 0,7,154,18,157,159:7:1 0,12,109,12,109,109:4:0 +X 1665 . T C,<*> 0 . DP=20;I16=7,11,1,1,592,20170,58,1924,1018,59282,89,4441,396,9188,39,821;QS=2.5913,0.408696,0;VDB=0.1;SGB=0.346553;RPB=0.222222;MQB=0.611111;MQSB=0.988166;BQB=0.944444;MQ0F=0 PL:DP:DV 0,21,185,21,185,185:7:0 0,27,222,27,222,222:9:0 35,0,51,41,57,90:4:2 +X 1666 . G <*> 0 . DP=20;I16=8,12,0,0,614,19760,0,0,1107,63723,0,0,435,9947,0,0;QS=3,0;MQSB=0.988166;MQ0F=0 PL:DP:DV 0,21,173:7:0 0,27,206:9:0 0,12,111:4:0 +X 1667 . G <*> 0 . DP=20;I16=8,11,0,0,617,21033,0,0,1078,62882,0,0,410,9276,0,0;QS=3,0;MQSB=0.992359;MQ0F=0 PL:DP:DV 0,21,183:7:0 0,24,195:8:0 0,12,115:4:0 +X 1668 . A <*> 0 . DP=20;I16=7,10,0,0,570,19908,0,0,958,55682,0,0,369,8365,0,0;QS=3,0;MQSB=0.989343;MQ0F=0 PL:DP:DV 0,18,158:6:0 0,21,186:7:0 0,12,124:4:0 +X 1669 . C <*> 0 . DP=20;I16=8,12,0,0,640,21336,0,0,1107,63723,0,0,435,9857,0,0;QS=3,0;MQSB=0.988166;MQ0F=0 PL:DP:DV 0,21,172:7:0 0,27,216:9:0 0,12,115:4:0 +X 1670 . A <*> 0 . DP=23;I16=9,13,0,0,765,27363,0,0,1258,73682,0,0,410,9234,0,0;QS=3,0;MQSB=0.991121;MQ0F=0 PL:DP:DV 0,27,215:9:0 0,27,233:9:0 0,12,129:4:0 +X 1671 . G <*> 0 . DP=23;I16=9,13,0,0,703,23631,0,0,1258,73682,0,0,412,9206,0,0;QS=3,0;MQSB=0.991121;MQ0F=0 PL:DP:DV 0,27,214:9:0 0,27,210:9:0 0,12,106:4:0 +X 1672 . T <*> 0 . DP=23;I16=9,13,0,0,724,24700,0,0,1258,73682,0,0,414,9202,0,0;QS=3,0;MQSB=0.991121;MQ0F=0 PL:DP:DV 0,27,203:9:0 0,27,232:9:0 0,12,111:4:0 +X 1673 . T <*> 0 . DP=25;I16=8,13,0,0,719,25183,0,0,1198,70082,0,0,372,8248,0,0;QS=3,0;MQSB=0.983744;MQ0F=0 PL:DP:DV 0,27,221:9:0 0,24,212:8:0 0,12,112:4:0 +X 1674 . C <*> 0 . DP=25;I16=8,14,0,0,755,26561,0,0,1289,76441,0,0,389,8417,0,0;QS=3,0;MQSB=0.892142;MQ0F=0 PL:DP:DV 0,33,244:11:0 0,21,206:7:0 0,12,96:4:0 +X 1675 . C <*> 0 . DP=25;I16=9,15,0,0,705,22355,0,0,1347,78123,0,0,447,9897,0,0;QS=3,0;MQSB=0.996008;MQ0F=0 PL:DP:DV 0,33,222:11:0 0,30,212:10:0 0,9,65:3:0 +X 1676 . G <*> 0 . DP=25;I16=6,15,0,0,660,21708,0,0,1167,67323,0,0,383,8265,0,0;QS=3,0;MQSB=0.993205;MQ0F=0 PL:DP:DV 0,33,222:11:0 0,21,170:7:0 0,9,96:3:0 +X 1677 . C <*> 0 . DP=25;I16=9,13,0,0,681,22869,0,0,1289,76441,0,0,394,8510,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,33,225:11:0 0,24,198:8:0 0,9,74:3:0 +X 1678 . C <*> 0 . DP=25;I16=9,15,0,0,775,26785,0,0,1347,78123,0,0,438,9496,0,0;QS=3,0;MQSB=0.996008;MQ0F=0 PL:DP:DV 0,33,235:11:0 0,30,231:10:0 0,9,83:3:0 +X 1679 . A <*> 0 . DP=25;I16=8,15,0,0,762,27552,0,0,1287,74523,0,0,412,8858,0,0;QS=3,0;MQSB=0.999479;MQ0F=0 PL:DP:DV 0,33,235:11:0 0,27,219:9:0 0,9,106:3:0 +X 1680 . G <*> 0 . DP=26;I16=9,17,0,0,843,29213,0,0,1467,85323,0,0,459,10021,0,0;QS=3,0;MQSB=0.999637;MQ0F=0 PL:DP:DV 0,33,253:11:0 0,33,232:11:0 0,12,108:4:0 +X 1681 . C <*> 0 . DP=26;I16=8,15,0,0,681,21293,0,0,1318,77282,0,0,407,8999,0,0;QS=3,0;MQSB=0.974802;MQ0F=0 PL:DP:DV 0,33,223:11:0 0,27,191:9:0 0,9,69:3:0 +X 1682 . G <*> 0 . DP=25;I16=9,16,0,0,728,22560,0,0,1407,81723,0,0,455,9877,0,0;QS=3,0;MQSB=0.998399;MQ0F=0 PL:DP:DV 0,30,222:10:0 0,33,208:11:0 0,12,98:4:0 +X 1683 . T <*> 0 . DP=25;I16=8,15,0,0,807,29159,0,0,1287,74523,0,0,403,8567,0,0;QS=3,0;MQSB=0.999479;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,30,235:10:0 0,9,91:3:0 +X 1684 . T <*> 0 . DP=25;I16=8,15,0,0,802,28774,0,0,1318,77282,0,0,438,9612,0,0;QS=3,0;MQSB=0.974802;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,30,237:10:0 0,12,107:4:0 +X 1685 . G <*> 0 . DP=24;I16=8,14,0,0,759,27319,0,0,1258,73682,0,0,413,8999,0,0;QS=3,0;MQSB=0.979255;MQ0F=0 PL:DP:DV 0,24,216:8:0 0,30,242:10:0 0,12,110:4:0 +X 1686 . C <*> 0 . DP=24;I16=8,15,0,0,793,28073,0,0,1318,77282,0,0,438,9656,0,0;QS=3,0;MQSB=0.974802;MQ0F=0 PL:DP:DV 0,27,225:9:0 0,30,241:10:0 0,12,103:4:0 +X 1687 . C <*> 0 . DP=24;I16=7,14,0,0,741,26765,0,0,1198,70082,0,0,388,8458,0,0;QS=3,0;MQSB=0.966484;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,27,229:9:0 0,12,106:4:0 +X 1688 . C <*> 0 . DP=24;I16=8,15,0,0,794,28736,0,0,1318,77282,0,0,431,9605,0,0;QS=3,0;MQSB=0.974802;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,30,221:10:0 0,12,120:4:0 +X 1689 . T A,<*> 0 . DP=24;I16=8,15,0,1,805,29443,33,1089,1287,74523,60,3600,421,9311,25,625;QS=2.74419,0.255814,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,27,224,27,224,224:9:0 0,33,255,33,255,255:11:0 21,0,79,30,82,106:4:1 +X 1690 . C <*> 0 . DP=24;I16=8,16,0,0,864,32420,0,0,1347,78123,0,0,445,10033,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,242:9:0 0,33,255:11:0 0,12,95:4:0 +X 1691 . T <*> 0 . DP=22;I16=7,14,0,0,734,27150,0,0,1167,67323,0,0,421,9525,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,225:9:0 0,30,242:10:0 0,6,57:2:0 +X 1692 . G <*> 0 . DP=22;I16=7,13,0,0,678,24110,0,0,1107,63723,0,0,400,9176,0,0;QS=3,0;MQSB=0.999215;MQ0F=0 PL:DP:DV 0,24,218:8:0 0,30,218:10:0 0,6,61:2:0 +X 1693 . T <*> 0 . DP=24;I16=10,13,0,0,795,28363,0,0,1318,77282,0,0,444,10422,0,0;QS=3,0;MQSB=0.995682;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,30,235:10:0 0,12,104:4:0 +X 1694 . T <*> 0 . DP=24;I16=10,13,0,0,771,26775,0,0,1318,77282,0,0,448,10602,0,0;QS=3,0;MQSB=0.995682;MQ0F=0 PL:DP:DV 0,27,221:9:0 0,30,232:10:0 0,12,114:4:0 +X 1695 . C <*> 0 . DP=24;I16=10,14,0,0,811,28517,0,0,1347,78123,0,0,454,10806,0,0;QS=3,0;MQSB=0.98469;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,33,239:11:0 0,12,121:4:0 +X 1696 . T <*> 0 . DP=23;I16=10,13,0,0,825,30819,0,0,1287,74523,0,0,455,10869,0,0;QS=3,0;MQSB=0.976718;MQ0F=0 PL:DP:DV 0,24,219:8:0 0,33,255:11:0 0,12,108:4:0 +X 1697 . G <*> 0 . DP=23;I16=10,13,0,0,767,26757,0,0,1287,74523,0,0,455,10897,0,0;QS=3,0;MQSB=0.976718;MQ0F=0 PL:DP:DV 0,24,208:8:0 0,33,246:11:0 0,12,112:4:0 +X 1698 . C A,<*> 0 . DP=21;I16=10,10,0,1,726,27088,27,729,1169,69241,29,841,451,10903,6,36;QS=2.91148,0.0885246,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.99938;BQB=1;MQ0F=0 PL:DP:DV 0,24,229,24,229,229:8:0 0,0,190,24,193,207:9:1 0,12,111,12,111,111:4:0 +X 1699 . T <*> 0 . DP=21;I16=9,10,0,0,698,25826,0,0,1078,62882,0,0,408,9692,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,21,203:7:0 0,24,219:8:0 0,12,115:4:0 +X 1700 . G <*> 0 . DP=20;I16=9,10,0,0,696,25850,0,0,1078,62882,0,0,409,9705,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,21,216:7:0 0,24,215:8:0 0,12,110:4:0 +X 1701 . T <*> 0 . DP=20;I16=9,11,0,0,711,25539,0,0,1138,66482,0,0,435,10353,0,0;QS=3,0;MQSB=0.997118;MQ0F=0 PL:DP:DV 0,24,207:8:0 0,24,210:8:0 0,12,125:4:0 +X 1702 . T <*> 0 . DP=20;I16=8,11,0,0,671,24367,0,0,1078,62882,0,0,410,9712,0,0;QS=3,0;MQSB=0.992359;MQ0F=0 PL:DP:DV 0,24,214:8:0 0,21,193:7:0 0,12,115:4:0 +X 1703 . T <*> 0 . DP=20;I16=9,10,0,0,648,22696,0,0,1078,62882,0,0,410,9708,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,21,197:7:0 0,24,195:8:0 0,12,114:4:0 +X 1704 . T <*> 0 . DP=20;I16=10,10,0,0,711,25771,0,0,1169,69241,0,0,435,10341,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,24,208:8:0 0,21,208:7:0 0,15,128:5:0 +X 1705 . C <*> 0 . DP=20;I16=10,10,0,0,744,28388,0,0,1169,69241,0,0,436,10312,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,24,232:8:0 0,21,213:7:0 0,15,120:5:0 +X 1706 . T <*> 0 . DP=20;I16=10,10,0,0,775,30329,0,0,1169,69241,0,0,436,10246,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,21,219:7:0 0,15,145:5:0 +X 1707 . C <*> 0 . DP=21;I16=9,11,0,0,724,26998,0,0,1169,69241,0,0,410,9518,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,27,235:9:0 0,18,180:6:0 0,15,134:5:0 +X 1708 . T <*> 0 . DP=21;I16=9,12,0,0,740,27282,0,0,1229,72841,0,0,410,9430,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,30,229:10:0 0,18,187:6:0 0,15,132:5:0 +X 1709 . A <*> 0 . DP=21;I16=9,11,0,0,675,23509,0,0,1169,69241,0,0,386,8734,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,27,210:9:0 0,18,166:6:0 0,15,131:5:0 +X 1710 . C <*> 0 . DP=22;I16=9,13,0,0,755,26817,0,0,1289,76441,0,0,412,9306,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,33,236:11:0 0,18,181:6:0 0,15,128:5:0 +X 1711 . C <*> 0 . DP=22;I16=9,13,0,0,786,28790,0,0,1289,76441,0,0,413,9223,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,33,250:11:0 0,18,169:6:0 0,15,138:5:0 +X 1712 . A <*> 0 . DP=22;I16=9,13,0,0,824,31342,0,0,1289,76441,0,0,414,9162,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,33,252:11:0 0,18,198:6:0 0,15,136:5:0 +X 1713 . G <*> 0 . DP=23;I16=8,14,0,0,823,31285,0,0,1289,76441,0,0,405,8993,0,0;QS=3,0;MQSB=0.892142;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,189:6:0 0,12,118:4:0 +X 1714 . A <*> 0 . DP=23;I16=9,13,0,0,763,27439,0,0,1289,76441,0,0,402,8818,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,36,234:12:0 0,18,190:6:0 0,12,101:4:0 +X 1715 . A <*> 0 . DP=23;I16=9,14,0,0,900,35416,0,0,1349,80041,0,0,414,8878,0,0;QS=3,0;MQSB=0.907354;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,206:6:0 0,15,145:5:0 +X 1716 . G <*> 0 . DP=23;I16=9,14,0,0,844,31500,0,0,1349,80041,0,0,414,8822,0,0;QS=3,0;MQSB=0.907354;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,188:6:0 0,15,129:5:0 +X 1717 . T <*> 0 . DP=24;I16=9,15,0,0,854,30878,0,0,1409,83641,0,0,414,8794,0,0;QS=3,0;MQSB=0.904837;MQ0F=0 PL:DP:DV 0,39,253:13:0 0,18,185:6:0 0,15,122:5:0 +X 1718 . G <*> 0 . DP=24;I16=9,14,0,0,806,29332,0,0,1349,80041,0,0,390,8170,0,0;QS=3,0;MQSB=0.907354;MQ0F=0 PL:DP:DV 0,36,249:12:0 0,18,188:6:0 0,15,124:5:0 +X 1719 . C <*> 0 . DP=26;I16=11,14,0,0,857,30717,0,0,1469,87241,0,0,407,8675,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,173:6:0 0,12,98:4:0 +X 1720 . C <*> 0 . DP=26;I16=11,14,0,0,898,33274,0,0,1469,87241,0,0,409,8645,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,166:6:0 0,12,99:4:0 +X 1721 . C <*> 0 . DP=26;I16=10,14,0,0,846,30642,0,0,1409,83641,0,0,388,8258,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,187:6:0 0,12,119:4:0 +X 1722 . T <*> 0 . DP=25;I16=11,13,0,0,876,33054,0,0,1409,83641,0,0,406,8540,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,174:5:0 0,15,123:5:0 +X 1723 . T <*> 0 . DP=25;I16=11,14,0,0,835,28861,0,0,1469,87241,0,0,420,8728,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,167:5:0 0,15,130:5:0 +X 1724 . C <*> 0 . DP=25;I16=11,14,0,0,903,33735,0,0,1469,87241,0,0,422,8800,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,164:5:0 0,15,139:5:0 +X 1725 . C G,<*> 0 . DP=25;I16=11,13,0,1,835,29699,25,625,1409,83641,60,3600,406,8576,18,324;QS=2.95164,0.0483559,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.929204;BQB=1;MQ0F=0 PL:DP:DV 0,20,255,42,255,255:15:1 0,15,153,15,153,153:5:0 0,15,132,15,132,132:5:0 +X 1726 . C <*> 0 . DP=25;I16=11,14,0,0,932,35588,0,0,1469,87241,0,0,426,9028,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,165:5:0 0,15,122:5:0 +X 1727 . T <*> 0 . DP=25;I16=10,14,0,0,862,32080,0,0,1409,83641,0,0,404,8556,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,167:5:0 0,12,120:4:0 +X 1728 . C <*> 0 . DP=25;I16=11,14,0,0,915,33845,0,0,1469,87241,0,0,429,9173,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,156:5:0 0,15,144:5:0 +X 1729 . C <*> 0 . DP=25;I16=10,14,0,0,919,35797,0,0,1409,83641,0,0,406,8668,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,142:5:0 0,12,128:4:0 +X 1730 . T <*> 0 . DP=24;I16=10,14,0,0,849,30711,0,0,1409,83641,0,0,433,9393,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,138:4:0 0,15,148:5:0 +X 1731 . C <*> 0 . DP=24;I16=10,14,0,0,907,34875,0,0,1409,83641,0,0,434,9472,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,123:4:0 0,15,140:5:0 +X 1732 . A <*> 0 . DP=24;I16=11,13,0,0,816,28582,0,0,1409,83641,0,0,436,9580,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,123:4:0 0,15,143:5:0 +X 1733 . C <*> 0 . DP=25;I16=12,13,0,0,869,31451,0,0,1469,87241,0,0,438,9666,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,116:4:0 0,15,136:5:0 +X 1734 . C <*> 0 . DP=25;I16=12,13,0,0,926,35482,0,0,1469,87241,0,0,440,9730,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,122:4:0 0,15,141:5:0 +X 1735 . T <*> 0 . DP=26;I16=13,13,0,0,935,35169,0,0,1529,90841,0,0,442,9822,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,112:4:0 0,15,148:5:0 +X 1736 . G <*> 0 . DP=25;I16=11,11,0,0,829,31469,0,0,1289,76441,0,0,380,8416,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,72:2:0 0,12,118:4:0 +X 1737 . A <*> 0 . DP=25;I16=12,12,0,0,842,30606,0,0,1409,83641,0,0,422,9312,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,76:2:0 0,15,131:5:0 +X 1738 . C <*> 0 . DP=24;I16=12,12,0,0,835,30251,0,0,1409,83641,0,0,450,10010,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,78:3:0 0,15,130:5:0 +X 1739 . C <*> 0 . DP=23;I16=10,12,0,0,831,32123,0,0,1289,76441,0,0,428,9432,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,55:2:0 0,12,135:4:0 +X 1740 . A <*> 0 . DP=23;I16=11,12,0,0,774,27126,0,0,1349,80041,0,0,456,10126,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,56:2:0 0,15,139:5:0 +X 1741 . C <*> 0 . DP=23;I16=11,12,0,0,850,32314,0,0,1349,80041,0,0,459,10217,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,70:2:0 0,15,136:5:0 +X 1742 . T <*> 0 . DP=23;I16=11,12,0,0,866,33204,0,0,1349,80041,0,0,462,10330,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,72:2:0 0,15,144:5:0 +X 1743 . C <*> 0 . DP=23;I16=11,12,0,0,894,35176,0,0,1349,80041,0,0,464,10414,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,74:2:0 0,15,138:5:0 +X 1744 . T <*> 0 . DP=23;I16=11,11,0,0,857,33579,0,0,1289,76441,0,0,459,10469,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,80:2:0 0,15,156:5:0 +X 1745 . G <*> 0 . DP=23;I16=11,12,0,0,882,34572,0,0,1349,80041,0,0,464,10442,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,78:2:0 0,15,142:5:0 +X 1746 . G <*> 0 . DP=24;I16=12,11,0,0,836,31102,0,0,1349,80041,0,0,456,10312,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,69:2:0 0,18,151:6:0 +X 1747 . G <*> 0 . DP=24;I16=12,11,0,0,839,31729,0,0,1349,80041,0,0,455,10239,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,75:2:0 0,18,154:6:0 +X 1748 . G <*> 0 . DP=24;I16=11,12,0,0,843,31857,0,0,1349,80041,0,0,434,9664,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,42:1:0 0,18,154:6:0 +X 1749 . A <*> 0 . DP=25;I16=13,11,0,0,864,31748,0,0,1409,83641,0,0,451,10063,0,0;QS=3,0;MQSB=0.950498;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,72:2:0 0,21,172:7:0 +X 1750 . A <*> 0 . DP=25;I16=13,12,0,0,905,33667,0,0,1469,87241,0,0,451,10013,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,56:2:0 0,21,187:7:0 +X 1751 . A <*> 0 . DP=25;I16=13,12,0,0,908,33658,0,0,1469,87241,0,0,449,9987,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,67:2:0 0,21,183:7:0 +X 1752 . T <*> 0 . DP=23;I16=12,11,0,0,838,31088,0,0,1380,82800,0,0,449,9987,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,71:2:0 0,18,170:6:0 +X 1753 . C <*> 0 . DP=23;I16=12,11,0,0,869,33595,0,0,1380,82800,0,0,448,9960,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,77:2:0 0,18,163:6:0 +X 1754 . C <*> 0 . DP=23;I16=11,11,0,0,830,31628,0,0,1320,79200,0,0,431,9699,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,3,42:1:0 0,18,163:6:0 +X 1755 . C <*> 0 . DP=23;I16=12,11,0,0,856,33082,0,0,1380,82800,0,0,446,9972,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,61:2:0 0,18,165:6:0 +X 1756 . T <*> 0 . DP=22;I16=11,11,0,0,858,33720,0,0,1320,79200,0,0,445,9961,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,77:2:0 0,18,179:6:0 +X 1757 . C <*> 0 . DP=22;I16=11,11,0,0,869,34651,0,0,1320,79200,0,0,444,9972,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,78:2:0 0,18,176:6:0 +X 1758 . A <*> 0 . DP=22;I16=11,11,0,0,865,34205,0,0,1320,79200,0,0,442,9954,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,81:2:0 0,18,177:6:0 +X 1759 . G <*> 0 . DP=22;I16=11,11,0,0,833,31965,0,0,1320,79200,0,0,439,9905,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,77:2:0 0,18,159:6:0 +X 1760 . C <*> 0 . DP=22;I16=11,11,0,0,849,33441,0,0,1320,79200,0,0,436,9874,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,79:2:0 0,18,159:6:0 +X 1761 . A <*> 0 . DP=22;I16=11,11,0,0,730,25766,0,0,1320,79200,0,0,432,9810,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,75:2:0 0,18,153:6:0 +X 1762 . C <*> 0 . DP=21;I16=11,10,0,0,767,28667,0,0,1260,75600,0,0,429,9761,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,76:2:0 0,18,160:6:0 +X 1763 . C <*> 0 . DP=21;I16=11,10,0,0,789,30115,0,0,1260,75600,0,0,426,9726,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,72:2:0 0,18,162:6:0 +X 1764 . C <*> 0 . DP=21;I16=11,10,0,0,821,32443,0,0,1260,75600,0,0,423,9705,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,72:2:0 0,18,167:6:0 +X 1765 . T <*> 0 . DP=21;I16=11,10,0,0,814,31746,0,0,1260,75600,0,0,420,9698,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,83:2:0 0,18,179:6:0 +X 1766 . C <*> 0 . DP=21;I16=11,10,0,0,796,30564,0,0,1260,75600,0,0,417,9705,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,71:2:0 0,18,162:6:0 +X 1767 . C <*> 0 . DP=21;I16=11,10,0,0,779,29559,0,0,1260,75600,0,0,414,9726,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,73:2:0 0,18,163:6:0 +X 1768 . C <*> 0 . DP=21;I16=11,10,0,0,798,30670,0,0,1260,75600,0,0,411,9761,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,68:2:0 0,18,160:6:0 +X 1769 . T <*> 0 . DP=21;I16=11,10,0,0,819,32179,0,0,1260,75600,0,0,406,9712,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,77:2:0 0,18,184:6:0 +X 1770 . G <*> 0 . DP=19;I16=11,8,0,0,699,26453,0,0,1140,68400,0,0,403,9679,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,68:2:0 0,18,158:6:0 +X 1771 . A <*> 0 . DP=18;I16=10,8,0,0,707,27853,0,0,1080,64800,0,0,401,9659,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,42:1:0 0,18,177:6:0 +X 1772 . G <*> 0 . DP=18;I16=10,8,0,0,669,25513,0,0,1080,64800,0,0,398,9600,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,38:1:0 0,18,159:6:0 +X 1773 . C <*> 0 . DP=17;I16=10,7,0,0,675,26897,0,0,1020,61200,0,0,396,9550,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,3,39:1:0 0,18,172:6:0 +X 1774 . A <*> 0 . DP=17;I16=10,7,0,0,653,25153,0,0,1020,61200,0,0,394,9508,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,3,39:1:0 0,18,172:6:0 +X 1775 . T <*> 0 . DP=17;I16=10,7,0,0,605,22253,0,0,1020,61200,0,0,391,9423,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,3,38:1:0 0,18,156:6:0 +X 1776 . A <*> 0 . DP=17;I16=10,7,0,0,610,22124,0,0,1020,61200,0,0,388,9344,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,254:10:0 0,3,35:1:0 0,18,166:6:0 +X 1777 . C <*> 0 . DP=18;I16=11,7,0,0,661,24975,0,0,1080,64800,0,0,385,9271,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,35:1:0 0,18,158:6:0 +X 1778 . C <*> 0 . DP=18;I16=11,7,0,0,680,25970,0,0,1080,64800,0,0,383,9205,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,31:1:0 0,18,172:6:0 +X 1779 . C <*> 0 . DP=18;I16=11,7,0,0,703,27663,0,0,1080,64800,0,0,381,9147,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,34:1:0 0,18,174:6:0 +X 1780 . T <*> 0 . DP=18;I16=11,7,0,0,672,26000,0,0,1080,64800,0,0,378,9048,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,33:1:0 0,18,177:6:0 +X 1781 . A <*> 0 . DP=19;I16=10,6,0,0,579,21377,0,0,960,57600,0,0,328,7804,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,0,0:0:0 0,15,160:5:0 +X 1782 . C <*> 0 . DP=20;I16=11,9,0,0,715,26603,0,0,1200,72000,0,0,382,8892,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,47:2:0 0,18,156:6:0 +X 1783 . T <*> 0 . DP=20;I16=11,9,0,0,755,29057,0,0,1200,72000,0,0,381,8743,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,68:2:0 0,18,184:6:0 +X 1784 . C <*> 0 . DP=20;I16=10,9,0,0,723,28017,0,0,1140,68400,0,0,360,8212,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,62:2:0 0,15,151:5:0 +X 1785 . T <*> 0 . DP=20;I16=10,10,0,0,766,29878,0,0,1200,72000,0,0,359,8089,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,66:2:0 0,15,168:5:0 +X 1786 . G <*> 0 . DP=22;I16=11,11,0,0,841,32323,0,0,1320,79200,0,0,359,7985,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,68:2:0 0,15,158:5:0 +X 1787 . G <*> 0 . DP=22;I16=11,11,0,0,806,30294,0,0,1320,79200,0,0,361,7903,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,68:2:0 0,15,148:5:0 +X 1788 . C <*> 0 . DP=22;I16=11,11,0,0,858,33674,0,0,1320,79200,0,0,362,7796,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,67:2:0 0,15,158:5:0 +X 1789 . A <*> 0 . DP=23;I16=11,12,0,0,797,28705,0,0,1380,82800,0,0,363,7715,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,69:2:0 0,15,157:5:0 +X 1790 . C <*> 0 . DP=23;I16=11,12,0,0,852,31816,0,0,1380,82800,0,0,365,7661,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,63:2:0 0,15,153:5:0 +X 1791 . A <*> 0 . DP=23;I16=11,12,0,0,830,30484,0,0,1380,82800,0,0,367,7635,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,61:2:0 0,15,155:5:0 +X 1792 . A <*> 0 . DP=23;I16=11,12,0,0,862,32760,0,0,1380,82800,0,0,368,7588,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,67:2:0 0,15,161:5:0 +X 1793 . G <*> 0 . DP=23;I16=11,12,0,0,813,29603,0,0,1380,82800,0,0,369,7571,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,61:2:0 0,15,126:5:0 +X 1794 . C <*> 0 . DP=21;I16=9,12,0,0,736,26472,0,0,1260,75600,0,0,370,7484,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,48:2:0 0,9,96:3:0 +X 1795 . C <*> 0 . DP=21;I16=9,12,0,0,763,28807,0,0,1260,75600,0,0,371,7427,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,45:2:0 0,9,100:3:0 +X 1796 . C <*> 0 . DP=21;I16=9,12,0,0,782,29718,0,0,1260,75600,0,0,372,7400,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,52:2:0 0,9,102:3:0 +X 1797 . A <*> 0 . DP=21;I16=9,12,0,0,704,25190,0,0,1260,75600,0,0,373,7403,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,59:2:0 0,9,92:3:0 +X 1798 . C <*> 0 . DP=21;I16=9,12,0,0,759,28119,0,0,1260,75600,0,0,374,7436,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,49:2:0 0,9,99:3:0 +X 1799 . C <*> 0 . DP=22;I16=9,13,0,0,796,29520,0,0,1320,79200,0,0,375,7499,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,56:2:0 0,12,131:4:0 +X 1800 . C <*> 0 . DP=22;I16=9,13,0,0,866,34352,0,0,1320,79200,0,0,376,7542,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,63:2:0 0,12,138:4:0 +X 1801 . T <*> 0 . DP=22;I16=9,13,0,0,838,32282,0,0,1320,79200,0,0,377,7615,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,63:2:0 0,12,150:4:0 +X 1802 . G <*> 0 . DP=22;I16=9,13,0,0,844,32894,0,0,1320,79200,0,0,378,7718,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,60:2:0 0,12,137:4:0 +X 1803 . C <*> 0 . DP=22;I16=9,13,0,0,837,32691,0,0,1320,79200,0,0,377,7751,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,60:2:0 0,12,143:4:0 +X 1804 . A <*> 0 . DP=23;I16=9,14,0,0,793,28517,0,0,1380,82800,0,0,376,7814,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,54:2:0 0,12,144:4:0 +X 1805 . A <*> 0 . DP=23;I16=9,14,0,0,810,29148,0,0,1380,82800,0,0,376,7908,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,67:2:0 0,12,138:4:0 +X 1806 . A <*> 0 . DP=23;I16=9,14,0,0,816,29932,0,0,1380,82800,0,0,376,8034,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,61:2:0 0,12,139:4:0 +X 1807 . G <*> 0 . DP=22;I16=9,13,0,0,837,32299,0,0,1320,79200,0,0,375,8091,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,67:2:0 0,12,142:4:0 +X 1808 . C <*> 0 . DP=21;I16=9,11,0,0,705,25519,0,0,1200,72000,0,0,354,7716,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,53:2:0 0,12,140:4:0 +X 1809 . C <*> 0 . DP=22;I16=10,12,0,0,789,29123,0,0,1320,79200,0,0,371,8091,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,55:2:0 0,12,143:4:0 +X 1810 . C <*> 0 . DP=21;I16=10,11,0,0,754,27902,0,0,1260,75600,0,0,370,8084,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,51:2:0 0,12,145:4:0 +X 1811 . C <*> 0 . DP=22;I16=11,11,0,0,837,32353,0,0,1320,79200,0,0,368,8056,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,61:2:0 0,12,146:4:0 +X 1812 . T <*> 0 . DP=22;I16=11,11,0,0,830,31782,0,0,1320,79200,0,0,365,7955,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,60:2:0 0,12,151:4:0 +X 1813 . G <*> 0 . DP=21;I16=11,10,0,0,789,29971,0,0,1260,75600,0,0,363,7879,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,63:2:0 0,12,135:4:0 +X 1814 . A <*> 0 . DP=21;I16=11,10,0,0,780,29356,0,0,1260,75600,0,0,361,7827,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,63:2:0 0,12,148:4:0 +X 1815 . G <*> 0 . DP=21;I16=11,10,0,0,742,27064,0,0,1260,75600,0,0,358,7748,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,56:2:0 0,12,135:4:0 +X 1816 . G <*> 0 . DP=21;I16=11,10,0,0,702,24670,0,0,1260,75600,0,0,355,7691,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,49:2:0 0,12,124:4:0 +X 1817 . C <*> 0 . DP=20;I16=11,9,0,0,701,25263,0,0,1200,72000,0,0,353,7655,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,58:2:0 0,12,134:4:0 +X 1818 . C <*> 0 . DP=20;I16=11,8,0,0,665,23987,0,0,1140,68400,0,0,326,7014,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,53:2:0 0,12,132:4:0 +X 1819 . C <*> 0 . DP=18;I16=9,9,0,0,580,20092,0,0,1080,64800,0,0,351,7641,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,38:2:0 0,12,124:4:0 +X 1820 . G <*> 0 . DP=18;I16=9,9,0,0,589,19883,0,0,1080,64800,0,0,351,7659,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,58:2:0 0,12,117:4:0 +X 1821 . C <*> 0 . DP=18;I16=9,9,0,0,619,22131,0,0,1080,64800,0,0,351,7693,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,60:2:0 0,12,131:4:0 +X 1822 . C <*> 0 . DP=18;I16=9,9,0,0,655,24177,0,0,1080,64800,0,0,350,7694,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,58:2:0 0,12,131:4:0 +X 1823 . C <*> 0 . DP=19;I16=10,9,0,0,703,26765,0,0,1140,68400,0,0,349,7713,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,62:2:0 0,12,138:4:0 +X 1824 . T <*> 0 . DP=19;I16=10,9,0,0,714,27628,0,0,1140,68400,0,0,349,7751,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,69:2:0 0,12,149:4:0 +X 1825 . G <*> 0 . DP=19;I16=10,9,0,0,682,24804,0,0,1140,68400,0,0,347,7709,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,61:2:0 0,12,129:4:0 +X 1826 . T <*> 0 . DP=19;I16=10,9,0,0,643,22525,0,0,1140,68400,0,0,345,7687,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,62:2:0 0,12,141:4:0 +X 1827 . G <*> 0 . DP=19;I16=10,9,0,0,722,27844,0,0,1140,68400,0,0,343,7685,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,66:2:0 0,12,134:4:0 +X 1828 . G <*> 0 . DP=18;I16=10,8,0,0,619,21719,0,0,1080,64800,0,0,342,7702,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,61:2:0 0,9,100:3:0 +X 1829 . C <*> 0 . DP=19;I16=9,9,0,0,576,19228,0,0,1080,64800,0,0,323,7413,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,59:3:0 0,9,103:3:0 +X 1830 . G <*> 0 . DP=19;I16=9,9,0,0,582,19586,0,0,1080,64800,0,0,321,7379,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,82:3:0 0,9,80:3:0 +X 1831 . T <*> 0 . DP=20;I16=10,8,0,0,605,21015,0,0,1080,64800,0,0,294,6736,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,106:4:0 0,9,101:3:0 +X 1832 . C <*> 0 . DP=19;I16=9,9,0,0,675,25747,0,0,1080,64800,0,0,319,7359,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,110:4:0 0,9,105:3:0 +X 1833 . T <*> 0 . DP=18;I16=8,8,0,0,565,20733,0,0,960,57600,0,0,295,6747,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,9,105:3:0 0,9,106:3:0 +X 1834 . C <*> 0 . DP=19;I16=9,9,0,0,654,24424,0,0,1037,61489,0,0,321,7399,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,104:4:0 0,9,107:3:0 +X 1835 . T <*> 0 . DP=18;I16=9,9,0,0,641,23505,0,0,1037,61489,0,0,347,7965,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,123:4:0 0,9,115:3:0 +X 1836 . C <*> 0 . DP=18;I16=9,9,0,0,657,24427,0,0,1037,61489,0,0,350,8016,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,127:4:0 0,9,108:3:0 +X 1837 . C <*> 0 . DP=18;I16=9,9,0,0,586,20044,0,0,1037,61489,0,0,352,8030,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,233:11:0 0,12,114:4:0 0,9,108:3:0 +X 1838 . C <*> 0 . DP=18;I16=9,9,0,0,655,24607,0,0,1037,61489,0,0,354,8056,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,120:4:0 0,9,107:3:0 +X 1839 . T <*> 0 . DP=18;I16=9,7,0,0,557,20543,0,0,917,54289,0,0,321,7369,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,30,231:10:0 0,9,103:3:0 0,9,119:3:0 +X 1840 . C <*> 0 . DP=18;I16=9,9,0,0,637,23295,0,0,1037,61489,0,0,358,8144,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,116:4:0 0,9,109:3:0 +X 1841 . C <*> 0 . DP=18;I16=9,9,0,0,622,22458,0,0,1037,61489,0,0,360,8206,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,252:11:0 0,12,121:4:0 0,9,108:3:0 +X 1842 . C <*> 0 . DP=18;I16=9,9,0,0,672,26064,0,0,1037,61489,0,0,362,8280,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,124:4:0 0,9,108:3:0 +X 1843 . T <*> 0 . DP=18;I16=9,9,0,0,630,22746,0,0,1037,61489,0,0,364,8366,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,243:11:0 0,12,131:4:0 0,9,107:3:0 +X 1844 . T <*> 0 . DP=18;I16=9,9,0,0,618,21618,0,0,1037,61489,0,0,366,8464,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,240:11:0 0,12,137:4:0 0,9,98:3:0 +X 1845 . G <*> 0 . DP=18;I16=9,9,0,0,644,23976,0,0,1037,61489,0,0,368,8574,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,138:4:0 0,9,82:3:0 +X 1846 . C <*> 0 . DP=18;I16=9,9,0,0,687,26809,0,0,1037,61489,0,0,370,8696,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,129:4:0 0,9,100:3:0 +X 1847 . T <*> 0 . DP=18;I16=9,9,0,0,675,25529,0,0,1037,61489,0,0,373,8829,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,132:4:0 0,6,76:2:0 +X 1848 . G <*> 0 . DP=18;I16=9,9,0,0,597,20845,0,0,1037,61489,0,0,377,8973,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,118:4:0 0,6,64:2:0 +X 1849 . T <*> 0 . DP=20;I16=9,10,0,0,614,20770,0,0,1097,65089,0,0,380,9078,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,119:4:0 0,6,71:2:0 +X 1850 . C <*> 0 . DP=19;I16=8,11,0,0,684,25154,0,0,1097,65089,0,0,409,9769,0,0;QS=3,0;MQSB=0.902014;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,120:4:0 0,3,37:1:0 +X 1851 . A <*> 0 . DP=20;I16=9,11,0,0,738,27838,0,0,1157,68689,0,0,413,9847,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,143:4:0 0,3,41:1:0 +X 1852 . G <*> 0 . DP=19;I16=8,11,0,0,639,22239,0,0,1097,65089,0,0,392,9264,0,0;QS=3,0;MQSB=0.902014;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,117:4:0 0,3,36:1:0 +X 1853 . G <*> 0 . DP=20;I16=9,11,0,0,627,20873,0,0,1157,68689,0,0,396,9322,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,127:5:0 0,3,38:1:0 +X 1854 . A <*> 0 . DP=22;I16=10,11,0,0,674,22428,0,0,1217,72289,0,0,401,9397,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,145:5:0 0,3,38:1:0 +X 1855 . C <*> 0 . DP=22;I16=10,12,0,0,771,27949,0,0,1277,75889,0,0,407,9441,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,132:5:0 0,3,37:1:0 +X 1856 . A <*> 0 . DP=22;I16=10,12,0,0,806,30230,0,0,1277,75889,0,0,412,9456,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,146:5:0 0,3,41:1:0 +X 1857 . G <*> 0 . DP=22;I16=10,12,0,0,699,23919,0,0,1277,75889,0,0,416,9442,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,134:5:0 0,3,35:1:0 +X 1858 . T <*> 0 . DP=23;I16=10,13,0,0,773,26797,0,0,1337,79489,0,0,419,9399,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,148:5:0 0,3,37:1:0 +X 1859 . G <*> 0 . DP=23;I16=10,13,0,0,798,28594,0,0,1337,79489,0,0,423,9379,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,146:5:0 0,3,36:1:0 +X 1860 . G <*> 0 . DP=23;I16=10,13,0,0,726,23842,0,0,1337,79489,0,0,425,9283,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,126:5:0 0,3,33:1:0 +X 1861 . T <*> 0 . DP=23;I16=10,13,0,0,741,24793,0,0,1337,79489,0,0,425,9113,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,143:5:0 0,3,39:1:0 +X 1862 . C <*> 0 . DP=23;I16=10,12,0,0,738,25732,0,0,1277,75889,0,0,403,8487,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,135:5:0 0,3,34:1:0 +X 1863 . C <*> 0 . DP=24;I16=10,13,0,0,804,29186,0,0,1337,79489,0,0,400,8232,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,133:5:0 0,3,36:1:0 +X 1864 . T <*> 0 . DP=24;I16=11,11,0,0,766,27572,0,0,1277,75889,0,0,392,8174,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,125:4:0 0,3,37:1:0 +X 1865 . G <*> 0 . DP=24;I16=11,13,0,0,860,31394,0,0,1397,83089,0,0,425,8621,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,154:5:0 0,3,38:1:0 +X 1866 . G <*> 0 . DP=24;I16=11,13,0,0,795,27503,0,0,1397,83089,0,0,425,8551,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,152:5:0 0,3,36:1:0 +X 1867 . C <*> 0 . DP=24;I16=9,13,0,0,726,24886,0,0,1320,79200,0,0,375,7263,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,122:5:0 0,3,38:1:0 +X 1868 . C <*> 0 . DP=24;I16=11,12,0,0,857,32293,0,0,1337,79489,0,0,411,8311,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,118:4:0 0,3,41:1:0 +X 1869 . A T,<*> 0 . DP=24;I16=6,9,5,4,531,19001,268,8660,857,50689,540,32400,273,5667,152,2866;QS=1.4724,1.5276,0;VDB=0.928022;SGB=-11.9537;RPB=0.984127;MQB=0.96464;MQSB=0.931547;BQB=0.359155;MQ0F=0 PL:DP:DV 115,0,224,148,245,255:18:7 16,0,104,28,107,128:5:1 42,3,0,42,3,42:1:1 +X 1870 . C <*> 0 . DP=25;I16=11,13,0,0,804,27826,0,0,1397,83089,0,0,425,8591,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,127:5:0 0,3,36:1:0 +X 1871 . C <*> 0 . DP=25;I16=11,14,0,0,761,24187,0,0,1457,86689,0,0,428,8690,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,128:6:0 0,3,29:1:0 +X 1872 . G <*> 0 . DP=25;I16=10,14,0,0,763,25437,0,0,1397,83089,0,0,425,8803,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,132:6:0 0,3,43:1:0 +X 1873 . G <*> 0 . DP=26;I16=11,15,0,0,790,25548,0,0,1517,90289,0,0,429,8931,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,151:7:0 0,3,43:1:0 +X 1874 . G <*> 0 . DP=27;I16=11,16,0,0,861,29013,0,0,1577,93889,0,0,430,9076,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,172:8:0 0,3,43:1:0 +X 1875 . G <*> 0 . DP=26;I16=11,15,0,0,800,26216,0,0,1517,90289,0,0,431,9155,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,168:7:0 0,3,42:1:0 +X 1876 . C <*> 0 . DP=26;I16=10,15,0,0,894,32714,0,0,1457,86689,0,0,432,9268,0,0;QS=3,0;MQSB=0.9171;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,171:7:0 0,3,41:1:0 +X 1877 . T <*> 0 . DP=25;I16=9,15,0,0,848,30804,0,0,1397,83089,0,0,409,8787,0,0;QS=3,0;MQSB=0.904837;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,163:6:0 0,3,42:1:0 +X 1878 . C <*> 0 . DP=25;I16=10,15,0,0,906,33478,0,0,1457,86689,0,0,434,9488,0,0;QS=3,0;MQSB=0.9171;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,166:7:0 0,3,40:1:0 +X 1879 . A <*> 0 . DP=26;I16=10,16,0,0,911,32761,0,0,1517,90289,0,0,433,9543,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,191:8:0 0,3,40:1:0 +X 1880 . C <*> 0 . DP=26;I16=10,16,0,0,790,24876,0,0,1517,90289,0,0,431,9527,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,152:8:0 0,3,31:1:0 +X 1881 . G <*> 0 . DP=27;I16=10,15,0,0,782,25352,0,0,1500,90000,0,0,380,8288,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,144:7:0 0,3,42:1:0 +X 1882 . G <*> 0 . DP=28;I16=12,15,0,0,937,33215,0,0,1577,93889,0,0,406,8952,0,0;QS=3,0;MQSB=0.935229;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,164:7:0 0,3,42:1:0 +X 1883 . A <*> 0 . DP=29;I16=14,15,0,0,998,35394,0,0,1697,101089,0,0,434,9646,0,0;QS=3,0;MQSB=0.947838;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,24,180:8:0 0,3,43:1:0 +X 1884 . G <*> 0 . DP=29;I16=14,15,0,0,1036,37926,0,0,1697,101089,0,0,437,9647,0,0;QS=3,0;MQSB=0.947838;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,24,202:8:0 0,3,42:1:0 +X 1885 . C <*> 0 . DP=28;I16=14,13,0,0,925,32305,0,0,1577,93889,0,0,430,9560,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,182:7:0 0,3,42:1:0 +X 1886 . C <*> 0 . DP=26;I16=13,13,0,0,826,27194,0,0,1517,90289,0,0,447,9745,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,166:8:0 0,3,32:1:0 +X 1887 . G <*> 0 . DP=26;I16=12,13,0,0,798,26554,0,0,1500,90000,0,0,428,9212,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,185:8:0 0,3,40:1:0 +X 1888 . C <*> 0 . DP=26;I16=13,13,0,0,901,32343,0,0,1517,90289,0,0,459,9957,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,178:8:0 0,3,39:1:0 +X 1889 . C <*> 0 . DP=25;I16=13,11,0,0,825,29127,0,0,1397,83089,0,0,444,9612,0,0;QS=3,0;MQSB=0.950498;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,187:7:0 0,3,37:1:0 +X 1890 . C <*> 0 . DP=25;I16=13,12,0,0,913,34029,0,0,1457,86689,0,0,471,10173,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,198:8:0 0,3,40:1:0 +X 1891 . T <*> 0 . DP=25;I16=13,12,0,0,912,34028,0,0,1457,86689,0,0,477,10317,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,212:8:0 0,3,39:1:0 +X 1892 . G <*> 0 . DP=25;I16=12,12,0,0,885,33149,0,0,1397,83089,0,0,458,9860,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,166:7:0 0,3,37:1:0 +X 1893 . T <*> 0 . DP=26;I16=14,12,0,0,920,33494,0,0,1517,90289,0,0,489,10677,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,205:8:0 0,6,72:2:0 +X 1894 . G <*> 0 . DP=26;I16=14,12,0,0,934,35048,0,0,1517,90289,0,0,495,10843,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,188:8:0 0,6,75:2:0 +X 1895 . C <*> 0 . DP=26;I16=13,12,0,0,882,31980,0,0,1500,90000,0,0,476,10408,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,180:8:0 0,6,73:2:0 +X 1896 . C <*> 0 . DP=26;I16=14,11,0,0,827,28179,0,0,1457,86689,0,0,482,10622,0,0;QS=3,0;MQSB=0.955682;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,154:7:0 0,6,72:2:0 +X 1897 . G <*> 0 . DP=26;I16=13,11,0,0,763,25169,0,0,1397,83089,0,0,486,10856,0,0;QS=3,0;MQSB=0.950498;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,164:7:0 0,3,27:1:0 +X 1898 . T <*> 0 . DP=27;I16=14,11,0,0,846,29526,0,0,1500,90000,0,0,492,11072,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,187:8:0 0,6,62:2:0 +X 1899 . G <*> 0 . DP=27;I16=14,11,0,0,875,32007,0,0,1500,90000,0,0,497,11213,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,188:8:0 0,6,61:2:0 +X 1900 . T <*> 0 . DP=26;I16=14,11,0,0,850,29882,0,0,1500,90000,0,0,501,11329,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,185:8:0 0,6,69:2:0 +X 1901 . A <*> 0 . DP=27;I16=15,10,0,0,842,29298,0,0,1457,86689,0,0,505,11469,0,0;QS=3,0;MQSB=0.962269;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,190:7:0 0,6,68:2:0 +X 1902 . C <*> 0 . DP=27;I16=15,12,0,0,912,31970,0,0,1577,93889,0,0,537,12267,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,184:8:0 0,6,60:2:0 +X 1903 . C <*> 0 . DP=27;I16=15,12,0,0,959,34645,0,0,1577,93889,0,0,542,12462,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,201:8:0 0,6,63:2:0 +X 1904 . T <*> 0 . DP=27;I16=16,11,0,0,1017,38757,0,0,1577,93889,0,0,548,12682,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,221:8:0 0,6,77:2:0 +X 1905 . C <*> 0 . DP=27;I16=16,11,0,0,985,36561,0,0,1577,93889,0,0,553,12827,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,211:8:0 0,6,69:2:0 +X 1906 . T <*> 0 . DP=27;I16=16,11,0,0,1018,39242,0,0,1577,93889,0,0,558,12998,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,207:8:0 0,6,75:2:0 +X 1907 . G <*> 0 . DP=27;I16=15,11,0,0,935,34679,0,0,1517,90289,0,0,535,12419,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,187:7:0 0,6,68:2:0 +X 1908 . A <*> 0 . DP=28;I16=16,12,0,0,1023,38221,0,0,1637,97489,0,0,561,13063,0,0;QS=3,0;MQSB=0.96195;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,215:8:0 0,6,67:2:0 +X 1909 . G <*> 0 . DP=27;I16=15,12,0,0,1002,38398,0,0,1577,93889,0,0,561,12953,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,206:8:0 0,6,73:2:0 +X 1910 . C <*> 0 . DP=27;I16=14,10,0,0,855,31251,0,0,1440,86400,0,0,502,11588,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,179:7:0 0,6,71:2:0 +X 1911 . C <*> 0 . DP=27;I16=15,12,0,0,967,35429,0,0,1577,93889,0,0,561,12793,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,206:8:0 0,6,71:2:0 +X 1912 . C <*> 0 . DP=27;I16=15,12,0,0,1024,39272,0,0,1577,93889,0,0,561,12743,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,217:8:0 0,6,73:2:0 +X 1913 . T <*> 0 . DP=27;I16=15,12,0,0,1028,39768,0,0,1577,93889,0,0,561,12713,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,228:8:0 0,6,77:2:0 +X 1914 . C <*> 0 . DP=27;I16=15,12,0,0,1010,38762,0,0,1577,93889,0,0,561,12703,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,221:8:0 0,6,75:2:0 +X 1915 . T C,<*> 0 . DP=27;I16=14,12,1,0,974,37184,16,256,1560,93600,17,289,543,12389,18,324;QS=2.97351,0.0264901,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.958048;BQB=1;MQ0F=0 PL:DP:DV 0,34,255,48,255,255:17:1 0,24,231,24,231,231:8:0 0,6,60,6,60,60:2:0 +X 1916 . G T,<*> 0 . DP=27;I16=14,12,1,0,991,38291,15,225,1560,93600,17,289,544,12454,17,289;QS=2.97581,0.0241935,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.958048;BQB=1;MQ0F=0 PL:DP:DV 0,35,255,48,255,255:17:1 0,24,226,24,226,226:8:0 0,6,69,6,69,69:2:0 +X 1917 . C <*> 0 . DP=27;I16=15,12,0,0,1030,39740,0,0,1577,93889,0,0,561,12793,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,214:8:0 0,6,73:2:0 +X 1918 . A <*> 0 . DP=27;I16=15,11,0,0,963,36201,0,0,1517,90289,0,0,542,12502,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,217:8:0 0,6,72:2:0 +X 1919 . C <*> 0 . DP=27;I16=15,12,0,0,987,36651,0,0,1577,93889,0,0,560,12902,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,214:8:0 0,6,72:2:0 +X 1920 . A T,<*> 0 . DP=29;I16=15,12,0,1,1007,38337,14,196,1546,91130,60,3600,538,12518,21,441;QS=2.97647,0.0235294,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.999735;BQB=1;MQ0F=0 PL:DP:DV 0,36,255,48,255,255:17:1 0,24,225,24,225,225:8:0 0,9,101,9,101,101:3:0 +X 1921 . G <*> 0 . DP=30;I16=15,14,0,0,1059,39815,0,0,1666,98330,0,0,542,12474,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,182:7:0 0,12,132:4:0 +X 1922 . T <*> 0 . DP=29;I16=14,14,0,0,1013,37513,0,0,1649,98041,0,0,532,12418,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,197:7:0 0,12,134:4:0 +X 1923 . G <*> 0 . DP=28;I16=14,14,0,0,1034,38974,0,0,1606,94730,0,0,545,12629,0,0;QS=3,0;MQSB=0.999736;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,188:7:0 0,12,126:4:0 +X 1924 . C <*> 0 . DP=27;I16=13,13,0,0,965,36587,0,0,1486,87530,0,0,521,12017,0,0;QS=3,0;MQSB=0.999671;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,183:7:0 0,12,116:4:0 +X 1925 . C <*> 0 . DP=27;I16=14,13,0,0,987,37021,0,0,1546,91130,0,0,546,12626,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,187:7:0 0,12,124:4:0 +X 1926 . T <*> 0 . DP=27;I16=14,13,0,0,1031,40057,0,0,1546,91130,0,0,545,12581,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,197:7:0 0,12,141:4:0 +X 1927 . T <*> 0 . DP=27;I16=13,13,0,0,959,35773,0,0,1529,90841,0,0,538,12522,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,191:7:0 0,12,133:4:0 +X 1928 . C <*> 0 . DP=27;I16=13,13,0,0,986,38264,0,0,1529,90841,0,0,538,12532,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,189:7:0 0,12,125:4:0 +X 1929 . T <*> 0 . DP=27;I16=13,13,0,0,990,38630,0,0,1529,90841,0,0,538,12562,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,189:7:0 0,12,139:4:0 +X 1930 . G <*> 0 . DP=26;I16=13,11,0,0,905,34865,0,0,1409,83641,0,0,521,12271,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,179:6:0 0,9,99:3:0 +X 1931 . C <*> 0 . DP=27;I16=15,12,0,0,967,36293,0,0,1546,91130,0,0,540,12578,0,0;QS=3,0;MQSB=0.99881;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,165:6:0 0,12,121:4:0 +X 1932 . T <*> 0 . DP=27;I16=14,13,0,0,998,38154,0,0,1546,91130,0,0,541,12605,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,143:5:0 0,15,146:5:0 +X 1933 . T <*> 0 . DP=27;I16=14,13,0,0,962,35344,0,0,1546,91130,0,0,542,12602,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,142:5:0 0,15,158:5:0 +X 1934 . G <*> 0 . DP=27;I16=13,13,0,0,987,38219,0,0,1529,90841,0,0,543,12569,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,134:5:0 0,15,143:5:0 +X 1935 . C <*> 0 . DP=27;I16=14,12,0,0,963,36627,0,0,1529,90841,0,0,520,11930,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,162:6:0 0,15,154:5:0 +X 1936 . C <*> 0 . DP=27;I16=14,13,0,0,1018,39406,0,0,1589,94441,0,0,547,12561,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,177:6:0 0,15,159:5:0 +X 1937 . T <*> 0 . DP=27;I16=14,13,0,0,1036,40636,0,0,1589,94441,0,0,547,12489,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,182:6:0 0,15,170:5:0 +X 1938 . G <*> 0 . DP=27;I16=14,13,0,0,1001,38377,0,0,1589,94441,0,0,546,12392,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,166:6:0 0,15,155:5:0 +X 1939 . T <*> 0 . DP=27;I16=14,12,0,0,964,36430,0,0,1560,93600,0,0,525,11909,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,167:6:0 0,12,144:4:0 +X 1940 . G <*> 0 . DP=27;I16=14,13,0,0,1003,37937,0,0,1589,94441,0,0,542,12172,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,159:6:0 0,15,155:5:0 +X 1941 . G <*> 0 . DP=27;I16=14,13,0,0,1004,38072,0,0,1589,94441,0,0,540,12098,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,176:6:0 0,15,156:5:0 +X 1942 . C <*> 0 . DP=27;I16=14,12,0,0,996,38790,0,0,1560,93600,0,0,516,11564,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,174:6:0 0,12,140:4:0 +X 1943 . T <*> 0 . DP=27;I16=14,13,0,0,1044,40952,0,0,1589,94441,0,0,536,12022,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,184:6:0 0,15,167:5:0 +X 1944 . T <*> 0 . DP=27;I16=14,13,0,0,987,37237,0,0,1589,94441,0,0,533,11971,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,175:6:0 0,15,170:5:0 +X 1945 . T <*> 0 . DP=27;I16=14,13,0,0,993,37067,0,0,1589,94441,0,0,530,11946,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,174:6:0 0,15,171:5:0 +X 1946 . G <*> 0 . DP=27;I16=14,13,0,0,1013,38617,0,0,1589,94441,0,0,526,11896,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,162:6:0 0,15,162:5:0 +X 1947 . A <*> 0 . DP=26;I16=13,13,0,0,950,35522,0,0,1529,90841,0,0,522,11818,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,167:6:0 0,15,160:5:0 +X 1948 . G C,<*> 0 . DP=27;I16=14,12,0,1,966,36912,16,256,1560,93600,29,841,493,11135,25,625;QS=2.90361,0.0963855,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.94394;BQB=1;MQ0F=0 PL:DP:DV 0,45,255,45,255,255:15:0 0,21,190,21,190,190:7:0 1,0,123,13,126,132:5:1 +X 1949 . A <*> 0 . DP=26;I16=14,11,0,0,871,31325,0,0,1469,87241,0,0,490,11048,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,174:7:0 0,15,155:5:0 +X 1950 . A <*> 0 . DP=27;I16=14,13,0,0,1007,38049,0,0,1589,94441,0,0,511,11559,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,205:7:0 0,18,176:6:0 +X 1951 . G <*> 0 . DP=27;I16=14,13,0,0,960,35536,0,0,1589,94441,0,0,509,11469,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,180:7:0 0,18,181:6:0 +X 1952 . A <*> 0 . DP=27;I16=14,12,0,0,924,33366,0,0,1529,90841,0,0,483,10779,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,184:7:0 0,18,182:6:0 +X 1953 . A <*> 0 . DP=28;I16=15,12,0,0,925,32719,0,0,1589,94441,0,0,482,10740,0,0;QS=3,0;MQSB=0.935229;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,189:7:0 0,18,168:6:0 +X 1954 . A C,<*> 0 . DP=29;I16=14,13,0,1,929,33219,18,324,1620,97200,29,841,475,10679,25,625;QS=2.90217,0.0978261,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.949591;BQB=1;MQ0F=0 PL:DP:DV 0,45,255,45,255,255:15:0 0,21,198,21,198,198:7:0 0,0,130,15,133,141:6:1 +X 1955 . C <*> 0 . DP=29;I16=14,12,0,0,961,36067,0,0,1560,93600,0,0,451,10035,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,206:7:0 0,15,165:5:0 +X 1956 . C <*> 0 . DP=29;I16=14,13,0,0,964,35402,0,0,1620,97200,0,0,475,10573,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,196:7:0 0,15,164:5:0 +X 1957 . C <*> 0 . DP=29;I16=14,13,0,0,980,36212,0,0,1620,97200,0,0,472,10420,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,183:7:0 0,15,167:5:0 +X 1958 . C <*> 0 . DP=29;I16=15,13,0,0,1003,37293,0,0,1649,98041,0,0,493,10825,0,0;QS=3,0;MQSB=0.942064;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,191:7:0 0,18,190:6:0 +X 1959 . T <*> 0 . DP=29;I16=16,13,0,0,1112,43258,0,0,1709,101641,0,0,491,10593,0,0;QS=3,0;MQSB=0.940317;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,213:7:0 0,18,193:6:0 +X 1960 . T <*> 0 . DP=30;I16=17,13,0,0,1053,37939,0,0,1769,105241,0,0,485,10339,0,0;QS=3,0;MQSB=0.938685;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,196:7:0 0,18,186:6:0 +X 1961 . C <*> 0 . DP=30;I16=17,13,0,0,1101,41737,0,0,1769,105241,0,0,480,10122,0,0;QS=3,0;MQSB=0.938685;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,195:7:0 0,18,183:6:0 +X 1962 . T <*> 0 . DP=29;I16=17,12,0,0,1134,44582,0,0,1709,101641,0,0,477,9941,0,0;QS=3,0;MQSB=0.931617;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,208:7:0 0,18,198:6:0 +X 1963 . G <*> 0 . DP=28;I16=16,12,0,0,1066,41050,0,0,1649,98041,0,0,476,9794,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,192:7:0 0,18,188:6:0 +X 1964 . G <*> 0 . DP=28;I16=16,12,0,0,970,34764,0,0,1649,98041,0,0,475,9681,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,178:7:0 0,18,169:6:0 +X 1965 . T <*> 0 . DP=29;I16=16,12,0,0,964,34772,0,0,1649,98041,0,0,449,8977,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,196:7:0 0,18,171:6:0 +X 1966 . T <*> 0 . DP=29;I16=16,13,0,0,1029,37027,0,0,1709,101641,0,0,474,9558,0,0;QS=3,0;MQSB=0.940317;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,191:7:0 0,18,181:6:0 +X 1967 . A <*> 0 . DP=29;I16=16,13,0,0,1030,37234,0,0,1709,101641,0,0,474,9550,0,0;QS=3,0;MQSB=0.940317;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,187:7:0 0,18,182:6:0 +X 1968 . T <*> 0 . DP=29;I16=16,13,0,0,1075,40173,0,0,1709,101641,0,0,474,9578,0,0;QS=3,0;MQSB=0.940317;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,195:7:0 0,18,190:6:0 +X 1969 . A <*> 0 . DP=28;I16=16,12,0,0,992,35828,0,0,1649,98041,0,0,474,9592,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,175:6:0 0,18,186:6:0 +X 1970 . C <*> 0 . DP=28;I16=16,12,0,0,1015,37503,0,0,1649,98041,0,0,474,9642,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,170:6:0 0,18,180:6:0 +X 1971 . A <*> 0 . DP=29;I16=16,13,0,0,1073,40273,0,0,1709,101641,0,0,474,9728,0,0;QS=3,0;MQSB=0.940317;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,178:6:0 0,21,206:7:0 +X 1972 . T <*> 0 . DP=30;I16=16,14,0,0,1068,38978,0,0,1769,105241,0,0,475,9851,0,0;QS=3,0;MQSB=0.946202;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,176:6:0 0,21,203:7:0 +X 1973 . A <*> 0 . DP=30;I16=16,13,0,0,1046,38070,0,0,1740,104400,0,0,452,9388,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,172:6:0 0,18,196:6:0 +X 1974 . A <*> 0 . DP=29;I16=16,13,0,0,1086,41474,0,0,1709,101641,0,0,477,10065,0,0;QS=3,0;MQSB=0.940317;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,157:5:0 0,21,214:7:0 +X 1975 . G <*> 0 . DP=28;I16=16,12,0,0,1067,41171,0,0,1649,98041,0,0,478,10156,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,133:4:0 0,21,195:7:0 +X 1976 . A <*> 0 . DP=28;I16=16,12,0,0,981,34839,0,0,1649,98041,0,0,478,10234,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,125:4:0 0,21,199:7:0 +X 1977 . C <*> 0 . DP=28;I16=16,12,0,0,1009,37471,0,0,1649,98041,0,0,477,10297,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,132:4:0 0,21,194:7:0 +X 1978 . A <*> 0 . DP=28;I16=16,12,0,0,1082,42132,0,0,1649,98041,0,0,476,10394,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,144:4:0 0,21,220:7:0 +X 1979 . G <*> 0 . DP=28;I16=16,11,0,0,1019,38927,0,0,1589,94441,0,0,454,10064,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,122:4:0 0,21,208:7:0 +X 1980 . C <*> 0 . DP=27;I16=16,10,0,0,932,34456,0,0,1529,90841,0,0,452,10114,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,107:3:0 0,21,197:7:0 +X 1981 . C <*> 0 . DP=28;I16=16,12,0,0,998,36510,0,0,1649,98041,0,0,469,10479,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,101:3:0 0,24,219:8:0 +X 1982 . A <*> 0 . DP=29;I16=16,12,0,0,1035,38815,0,0,1649,98041,0,0,472,10548,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,110:3:0 0,27,254:9:0 +X 1983 . G <*> 0 . DP=28;I16=16,12,0,0,1048,40322,0,0,1649,98041,0,0,477,10599,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,96:3:0 0,27,249:9:0 +X 1984 . A <*> 0 . DP=27;I16=16,11,0,0,1024,39232,0,0,1589,94441,0,0,482,10632,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,70:2:0 0,27,255:9:0 +X 1985 . G <*> 0 . DP=27;I16=16,11,0,0,1009,38449,0,0,1589,94441,0,0,487,10695,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,66:2:0 0,27,231:9:0 +X 1986 . A <*> 0 . DP=27;I16=16,10,0,0,926,33696,0,0,1560,93600,0,0,466,10112,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,76:2:0 0,24,223:8:0 +X 1987 . A <*> 0 . DP=28;I16=17,11,0,0,1034,39088,0,0,1649,98041,0,0,495,10807,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,78:2:0 0,27,247:9:0 +X 1988 . G <*> 0 . DP=28;I16=17,11,0,0,1050,39980,0,0,1649,98041,0,0,499,10855,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,63:2:0 0,27,239:9:0 +X 1989 . G <*> 0 . DP=28;I16=17,10,0,0,994,37610,0,0,1589,94441,0,0,493,10801,0,0;QS=3,0;MQSB=0.912952;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,73:2:0 0,27,237:9:0 +X 1990 . G T,<*> 0 . DP=28;I16=17,9,0,1,965,36359,33,1089,1560,93600,29,841,472,10250,25,625;QS=2.90675,0.0932476,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.912952;BQB=1;MQ0F=0 PL:DP:DV 0,48,255,48,255,255:16:0 0,6,71,6,71,71:2:0 2,0,195,26,198,215:9:1 +X 1991 . A <*> 0 . DP=28;I16=17,11,0,0,1017,38203,0,0,1649,98041,0,0,507,10975,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,60:2:0 0,27,250:9:0 +X 1992 . G <*> 0 . DP=28;I16=17,11,0,0,1028,38852,0,0,1649,98041,0,0,509,11039,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,62:2:0 0,27,231:9:0 +X 1993 . T <*> 0 . DP=28;I16=17,11,0,0,1015,37325,0,0,1649,98041,0,0,511,11131,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,59:2:0 0,27,243:9:0 +X 1994 . T <*> 0 . DP=27;I16=16,11,0,0,942,33698,0,0,1589,94441,0,0,514,11250,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,54:2:0 0,24,216:8:0 +X 1995 . G <*> 0 . DP=28;I16=16,11,0,0,960,35432,0,0,1620,97200,0,0,492,10770,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,66:2:0 0,21,188:7:0 +X 1996 . C <*> 0 . DP=29;I16=17,12,0,0,1022,37426,0,0,1709,101641,0,0,519,11469,0,0;QS=3,0;MQSB=0.931617;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,64:2:0 0,24,192:8:0 +X 1997 . C <*> 0 . DP=29;I16=17,11,0,0,934,32858,0,0,1649,98041,0,0,520,11524,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,70:2:0 0,24,193:8:0 +X 1998 . C <*> 0 . DP=29;I16=17,12,0,0,1027,37843,0,0,1709,101641,0,0,522,11562,0,0;QS=3,0;MQSB=0.931617;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,69:2:0 0,24,222:8:0 +X 1999 . A <*> 0 . DP=28;I16=17,11,0,0,1073,41493,0,0,1649,98041,0,0,525,11627,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,72:2:0 0,21,206:7:0 +X 2000 . G <*> 0 . DP=28;I16=16,11,0,0,1036,40576,0,0,1589,94441,0,0,511,11395,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,72:2:0 0,18,168:6:0 +X 2001 . G <*> 0 . DP=28;I16=15,11,0,0,955,35661,0,0,1529,90841,0,0,489,10853,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,62:2:0 0,18,172:6:0 +X 2002 . G <*> 0 . DP=28;I16=17,10,0,0,907,32227,0,0,1620,97200,0,0,519,11663,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,53:2:0 0,18,163:6:0 +X 2003 . T <*> 0 . DP=28;I16=17,11,0,0,920,31866,0,0,1649,98041,0,0,541,12163,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,49:2:0 0,21,190:7:0 +X 2004 . G <*> 0 . DP=27;I16=16,10,0,0,970,36928,0,0,1560,93600,0,0,530,12110,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,57:2:0 0,18,178:6:0 +X 2005 . G <*> 0 . DP=27;I16=16,10,0,0,868,30936,0,0,1560,93600,0,0,536,12370,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,59:2:0 0,18,153:6:0 +X 2006 . C <*> 0 . DP=27;I16=16,10,0,0,968,37046,0,0,1560,93600,0,0,541,12605,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,73:2:0 0,18,166:6:0 +X 2007 . A <*> 0 . DP=27;I16=16,11,0,0,1000,37396,0,0,1589,94441,0,0,556,12882,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,76:2:0 0,21,193:7:0 +X 2008 . C <*> 0 . DP=26;I16=16,10,0,0,964,36892,0,0,1529,90841,0,0,555,12833,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,73:2:0 0,21,183:7:0 +X 2009 . A <*> 0 . DP=26;I16=16,10,0,0,997,38955,0,0,1529,90841,0,0,554,12802,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,74:2:0 0,21,210:7:0 +X 2010 . G <*> 0 . DP=26;I16=16,9,0,0,936,36208,0,0,1500,90000,0,0,542,12640,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,73:2:0 0,18,169:6:0 +X 2011 . C <*> 0 . DP=26;I16=16,9,0,0,966,37960,0,0,1500,90000,0,0,541,12617,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,74:2:0 0,18,175:6:0 +X 2012 . A <*> 0 . DP=27;I16=16,11,0,0,956,35018,0,0,1589,94441,0,0,548,12676,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,74:2:0 0,21,189:7:0 +X 2013 . C <*> 0 . DP=27;I16=15,10,0,0,876,31370,0,0,1500,90000,0,0,514,11950,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,69:2:0 0,18,160:6:0 +X 2014 . G <*> 0 . DP=27;I16=17,10,0,0,903,31239,0,0,1589,94441,0,0,545,12591,0,0;QS=3,0;MQSB=0.912952;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,80:3:0 0,18,160:6:0 +X 2015 . T <*> 0 . DP=27;I16=17,10,0,0,999,37507,0,0,1589,94441,0,0,545,12577,0,0;QS=3,0;MQSB=0.912952;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,95:3:0 0,18,178:6:0 +X 2016 . T <*> 0 . DP=27;I16=17,10,0,0,971,35649,0,0,1589,94441,0,0,545,12583,0,0;QS=3,0;MQSB=0.912952;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,93:3:0 0,18,178:6:0 +X 2017 . G <*> 0 . DP=28;I16=17,11,0,0,1013,37849,0,0,1649,98041,0,0,545,12609,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,9,91:3:0 0,18,172:6:0 +X 2018 . C <*> 0 . DP=28;I16=17,11,0,0,1060,41414,0,0,1649,98041,0,0,546,12656,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,9,97:3:0 0,18,169:6:0 +X 2019 . T <*> 0 . DP=28;I16=17,11,0,0,1083,42253,0,0,1649,98041,0,0,547,12725,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,9,106:3:0 0,18,187:6:0 +X 2020 . G <*> 0 . DP=29;I16=18,11,0,0,1095,42063,0,0,1678,98882,0,0,548,12816,0,0;QS=3,0;MQSB=0.987702;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,9,85:3:0 0,18,175:6:0 +X 2021 . C <*> 0 . DP=29;I16=18,11,0,0,1081,41535,0,0,1709,101641,0,0,551,12877,0,0;QS=3,0;MQSB=0.969907;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,97:3:0 0,15,167:5:0 +X 2022 . C <*> 0 . DP=30;I16=19,11,0,0,1115,42003,0,0,1769,105241,0,0,555,12907,0,0;QS=3,0;MQSB=0.972375;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,92:3:0 0,18,177:6:0 +X 2023 . A <*> 0 . DP=30;I16=19,10,0,0,1063,39991,0,0,1709,101641,0,0,549,12837,0,0;QS=3,0;MQSB=0.974027;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,9,96:3:0 0,18,186:6:0 +X 2024 . G <*> 0 . DP=32;I16=20,12,0,0,1168,43872,0,0,1889,112441,0,0,564,12982,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,92:3:0 0,24,203:8:0 +X 2025 . T <*> 0 . DP=32;I16=20,12,0,0,1150,42122,0,0,1889,112441,0,0,569,12981,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,87:3:0 0,24,226:8:0 +X 2026 . T <*> 0 . DP=32;I16=20,12,0,0,1130,40724,0,0,1889,112441,0,0,572,12908,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,94:3:0 0,24,208:8:0 +X 2027 . A <*> 0 . DP=32;I16=19,12,0,0,1121,40871,0,0,1829,108841,0,0,550,12240,0,0;QS=3,0;MQSB=0.970829;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,84:3:0 0,21,207:7:0 +X 2028 . C <*> 0 . DP=32;I16=20,12,0,0,1242,48548,0,0,1889,112441,0,0,577,12803,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,94:3:0 0,24,228:8:0 +X 2029 . T <*> 0 . DP=32;I16=20,12,0,0,1229,47605,0,0,1889,112441,0,0,578,12724,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,102:3:0 0,24,236:8:0 +X 2030 . G <*> 0 . DP=32;I16=20,12,0,0,1222,47140,0,0,1889,112441,0,0,579,12679,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,93:3:0 0,24,216:8:0 +X 2031 . C <*> 0 . DP=31;I16=19,12,0,0,1150,43656,0,0,1829,108841,0,0,581,12667,0,0;QS=3,0;MQSB=0.970829;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,9,96:3:0 0,24,204:8:0 +X 2032 . C <*> 0 . DP=31;I16=19,12,0,0,1157,44035,0,0,1829,108841,0,0,583,12687,0,0;QS=3,0;MQSB=0.970829;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,9,90:3:0 0,24,210:8:0 +X 2033 . A <*> 0 . DP=30;I16=19,11,0,0,1091,40223,0,0,1769,105241,0,0,585,12689,0,0;QS=3,0;MQSB=0.972375;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,9,93:3:0 0,21,203:7:0 +X 2034 . T <*> 0 . DP=30;I16=19,11,0,0,1104,41498,0,0,1769,105241,0,0,587,12723,0,0;QS=3,0;MQSB=0.972375;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,9,91:3:0 0,21,208:7:0 +X 2035 . T <*> 0 . DP=29;I16=18,11,0,0,1084,41024,0,0,1709,101641,0,0,589,12739,0,0;QS=3,0;MQSB=0.969907;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,69:2:0 0,21,211:7:0 +X 2036 . T <*> 0 . DP=29;I16=18,11,0,0,1080,40612,0,0,1709,101641,0,0,591,12787,0,0;QS=3,0;MQSB=0.969907;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,67:2:0 0,21,216:7:0 +X 2037 . T <*> 0 . DP=29;I16=18,11,0,0,1082,40956,0,0,1709,101641,0,0,592,12818,0,0;QS=3,0;MQSB=0.969907;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,69:2:0 0,21,217:7:0 +X 2038 . C <*> 0 . DP=29;I16=18,11,0,0,1117,43573,0,0,1709,101641,0,0,592,12832,0,0;QS=3,0;MQSB=0.969907;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,69:2:0 0,21,211:7:0 +X 2039 . A <*> 0 . DP=29;I16=18,11,0,0,1067,39581,0,0,1709,101641,0,0,592,12878,0,0;QS=3,0;MQSB=0.969907;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,72:2:0 0,21,212:7:0 +X 2040 . C <*> 0 . DP=29;I16=18,11,0,0,1077,40469,0,0,1709,101641,0,0,590,12856,0,0;QS=3,0;MQSB=0.969907;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,69:2:0 0,21,196:7:0 +X 2041 . G A,<*> 0 . DP=31;I16=6,5,12,7,389,14023,721,28149,660,39600,1109,65641,235,5607,353,7259;QS=0.917304,2.0827,0;VDB=0.816435;SGB=-4.18892;RPB=0.88473;MQB=0.972375;MQSB=0.968257;BQB=0.311275;MQ0F=0 PL:DP:DV 229,0,212,255,245,255:21:11 32,0,24,35,27,59:2:1 223,21,0,223,21,223:7:7 +X 2042 . G <*> 0 . DP=32;I16=18,14,0,0,1189,45617,0,0,1889,112441,0,0,588,12910,0,0;QS=3,0;MQSB=0.965264;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,9,86:3:0 0,21,206:7:0 +X 2043 . G <*> 0 . DP=32;I16=17,14,0,0,1115,41585,0,0,1829,108841,0,0,581,12891,0,0;QS=3,0;MQSB=0.962133;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,90:3:0 0,21,197:7:0 +X 2044 . C <*> 0 . DP=32;I16=18,14,0,0,1213,47029,0,0,1889,112441,0,0,588,13006,0,0;QS=3,0;MQSB=0.965264;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,9,85:3:0 0,21,207:7:0 +X 2045 . A <*> 0 . DP=32;I16=18,14,0,0,1181,44527,0,0,1889,112441,0,0,588,13108,0,0;QS=3,0;MQSB=0.965264;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,9,83:3:0 0,21,213:7:0 +X 2046 . T <*> 0 . DP=32;I16=18,14,0,0,1197,45135,0,0,1889,112441,0,0,587,13195,0,0;QS=3,0;MQSB=0.965264;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,9,103:3:0 0,21,216:7:0 +X 2047 . G <*> 0 . DP=34;I16=17,16,0,0,1248,47798,0,0,1949,116041,0,0,557,12491,0,0;QS=3,0;MQSB=0.959328;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,9,88:3:0 0,18,195:6:0 +X 2048 . A <*> 0 . DP=34;I16=18,16,0,0,1230,45184,0,0,2009,119641,0,0,578,13022,0,0;QS=3,0;MQSB=0.962621;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,9,87:3:0 0,21,206:7:0 +X 2049 . A <*> 0 . DP=33;I16=17,16,0,0,1207,44567,0,0,1949,116041,0,0,575,12963,0,0;QS=3,0;MQSB=0.959328;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,6,74:2:0 0,21,208:7:0 +X 2050 . A <*> 0 . DP=33;I16=16,16,0,0,1169,43313,0,0,1889,112441,0,0,545,12211,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,6,77:2:0 0,18,188:6:0 +X 2051 . T <*> 0 . DP=31;I16=16,15,0,0,1134,42164,0,0,1829,108841,0,0,567,12737,0,0;QS=3,0;MQSB=0.957006;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,6,69:2:0 0,18,170:6:0 +X 2052 . G <*> 0 . DP=31;I16=16,15,0,0,1180,45546,0,0,1829,108841,0,0,564,12664,0,0;QS=3,0;MQSB=0.957006;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,6,74:2:0 0,18,175:6:0 +X 2053 . G T,<*> 0 . DP=31;I16=15,15,0,1,1126,42672,23,529,1769,105241,60,3600,537,11991,25,625;QS=2.97307,0.0269321,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.951229;BQB=1;MQ0F=0 PL:DP:DV 0,46,255,66,255,255:23:1 0,6,71,6,71,71:2:0 0,18,180,18,180,180:6:0 +X 2054 . A <*> 0 . DP=30;I16=15,15,0,0,1123,43027,0,0,1769,105241,0,0,562,12592,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,6,78:2:0 0,18,171:6:0 +X 2055 . G <*> 0 . DP=30;I16=15,15,0,0,1156,45206,0,0,1769,105241,0,0,562,12592,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,6,66:2:0 0,18,168:6:0 +X 2056 . A <*> 0 . DP=30;I16=15,15,0,0,1124,42416,0,0,1769,105241,0,0,560,12518,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,6,71:2:0 0,18,179:6:0 +X 2057 . T <*> 0 . DP=30;I16=15,15,0,0,1094,40082,0,0,1769,105241,0,0,556,12374,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,6,72:2:0 0,18,178:6:0 +X 2058 . A <*> 0 . DP=29;I16=14,15,0,0,1035,37517,0,0,1709,101641,0,0,552,12212,0,0;QS=3,0;MQSB=0.947838;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,6,57:2:0 0,18,179:6:0 +X 2059 . A <*> 0 . DP=29;I16=14,15,0,0,1063,39615,0,0,1709,101641,0,0,548,12082,0,0;QS=3,0;MQSB=0.947838;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,6,66:2:0 0,18,188:6:0 +X 2060 . C <*> 0 . DP=28;I16=12,15,0,0,1015,39057,0,0,1589,94441,0,0,523,11499,0,0;QS=3,0;MQSB=0.935229;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,62:2:0 0,15,143:5:0 +X 2061 . A <*> 0 . DP=27;I16=12,14,0,0,950,35084,0,0,1529,90841,0,0,501,11073,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,3,41:1:0 0,15,163:5:0 +X 2062 . A <*> 0 . DP=26;I16=11,15,0,0,973,37349,0,0,1529,90841,0,0,519,11425,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,57:2:0 0,15,164:5:0 +X 2063 . C <*> 0 . DP=26;I16=11,15,0,0,1017,40149,0,0,1529,90841,0,0,517,11405,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,74:2:0 0,15,158:5:0 +X 2064 . A <*> 0 . DP=26;I16=11,15,0,0,1002,38980,0,0,1529,90841,0,0,515,11413,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,75:2:0 0,15,164:5:0 +X 2065 . G <*> 0 . DP=26;I16=12,14,0,0,1030,41232,0,0,1529,90841,0,0,514,11448,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,78:2:0 0,18,167:6:0 +X 2066 . G <*> 0 . DP=26;I16=12,14,0,0,973,37055,0,0,1529,90841,0,0,514,11510,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,75:2:0 0,18,152:6:0 +X 2067 . A <*> 0 . DP=26;I16=12,14,0,0,1005,39095,0,0,1529,90841,0,0,512,11498,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,69:2:0 0,18,187:6:0 +X 2068 . G <*> 0 . DP=26;I16=12,14,0,0,993,39005,0,0,1529,90841,0,0,509,11459,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,53:2:0 0,18,167:6:0 +X 2069 . C <*> 0 . DP=26;I16=12,14,0,0,873,29879,0,0,1529,90841,0,0,506,11442,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,59:2:0 0,18,156:6:0 +X 2070 . G <*> 0 . DP=27;I16=13,14,0,0,932,33090,0,0,1589,94441,0,0,502,11398,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,62:2:0 0,18,145:6:0 +X 2071 . A <*> 0 . DP=27;I16=13,14,0,0,946,33884,0,0,1589,94441,0,0,498,11330,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,53:2:0 0,18,177:6:0 +X 2072 . C <*> 0 . DP=25;I16=13,12,0,0,897,32897,0,0,1469,87241,0,0,496,11288,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,59:2:0 0,15,128:5:0 +X 2073 . C <*> 0 . DP=26;I16=14,12,0,0,874,30184,0,0,1529,90841,0,0,492,11168,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,53:2:0 0,15,133:5:0 +X 2074 . G <*> 0 . DP=26;I16=13,12,0,0,835,29219,0,0,1469,87241,0,0,463,10395,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,67:2:0 0,12,83:4:0 +X 2075 . C <*> 0 . DP=27;I16=15,12,0,0,989,37027,0,0,1589,94441,0,0,484,10896,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,69:2:0 0,15,115:5:0 +X 2076 . A <*> 0 . DP=27;I16=14,12,0,0,929,33551,0,0,1529,90841,0,0,470,10676,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,76:2:0 0,12,114:4:0 +X 2077 . C <*> 0 . DP=27;I16=15,12,0,0,990,37252,0,0,1589,94441,0,0,478,10724,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,65:2:0 0,15,125:5:0 +X 2078 . A <*> 0 . DP=27;I16=15,12,0,0,1023,39089,0,0,1589,94441,0,0,475,10677,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,72:2:0 0,15,148:5:0 +X 2079 . G <*> 0 . DP=28;I16=15,13,0,0,1042,39694,0,0,1649,98041,0,0,471,10605,0,0;QS=3,0;MQSB=0.956162;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,6,72:2:0 0,15,133:5:0 +X 2080 . G <*> 0 . DP=28;I16=14,13,0,0,968,35328,0,0,1589,94441,0,0,453,10333,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,6,67:2:0 0,12,108:4:0 +X 2081 . C <*> 0 . DP=26;I16=14,12,0,0,937,35303,0,0,1529,90841,0,0,467,10535,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,63:2:0 0,15,110:5:0 +X 2082 . T <*> 0 . DP=24;I16=12,12,0,0,901,34287,0,0,1409,83641,0,0,468,10532,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,71:2:0 0,12,112:4:0 +X 2083 . G <*> 0 . DP=24;I16=12,12,0,0,887,33597,0,0,1409,83641,0,0,469,10547,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,68:2:0 0,12,113:4:0 +X 2084 . C <*> 0 . DP=25;I16=13,12,0,0,938,35868,0,0,1469,87241,0,0,470,10580,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,61:2:0 0,12,115:4:0 +X 2085 . T <*> 0 . DP=25;I16=13,12,0,0,932,35282,0,0,1469,87241,0,0,472,10632,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,64:2:0 0,12,130:4:0 +X 2086 . G <*> 0 . DP=25;I16=13,12,0,0,932,35400,0,0,1469,87241,0,0,474,10704,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,61:2:0 0,12,129:4:0 +X 2087 . A <*> 0 . DP=24;I16=12,12,0,0,903,34391,0,0,1409,83641,0,0,476,10746,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,66:2:0 0,12,126:4:0 +X 2088 . G <*> 0 . DP=24;I16=12,12,0,0,880,33116,0,0,1409,83641,0,0,478,10808,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,70:2:0 0,12,121:4:0 +X 2089 . C <*> 0 . DP=25;I16=13,12,0,0,817,27419,0,0,1469,87241,0,0,480,10890,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,64:2:0 0,15,138:5:0 +X 2090 . G <*> 0 . DP=25;I16=12,12,0,0,802,27940,0,0,1409,83641,0,0,457,10319,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,63:2:0 0,12,99:4:0 +X 2091 . C <*> 0 . DP=25;I16=12,12,0,0,800,27346,0,0,1440,86400,0,0,458,10346,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,61:2:0 0,15,125:5:0 +X 2092 . G <*> 0 . DP=26;I16=13,12,0,0,838,29188,0,0,1469,87241,0,0,461,10487,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,64:2:0 0,18,133:6:0 +X 2093 . T G,<*> 0 . DP=26;I16=13,12,1,0,905,33415,17,289,1500,90000,29,841,459,10371,25,625;QS=2.97424,0.0257576,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.953497;BQB=1;MQ0F=0 PL:DP:DV 0,36,255,51,255,255:18:1 0,6,67,6,67,67:2:0 0,18,153,18,153,153:6:0 +X 2094 . C <*> 0 . DP=26;I16=14,12,0,0,949,35501,0,0,1529,90841,0,0,485,11047,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,69:2:0 0,18,142:6:0 +X 2095 . A <*> 0 . DP=25;I16=14,11,0,0,879,31219,0,0,1469,87241,0,0,487,11123,0,0;QS=3,0;MQSB=0.955682;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,72:2:0 0,18,154:6:0 +X 2096 . C <*> 0 . DP=24;I16=13,11,0,0,878,32734,0,0,1409,83641,0,0,487,11073,0,0;QS=3,0;MQSB=0.950498;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,65:2:0 0,18,161:6:0 +X 2097 . A <*> 0 . DP=24;I16=13,11,0,0,849,30671,0,0,1409,83641,0,0,487,11047,0,0;QS=3,0;MQSB=0.950498;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,56:2:0 0,18,172:6:0 +X 2098 . C <*> 0 . DP=24;I16=13,11,0,0,781,26113,0,0,1409,83641,0,0,486,10996,0,0;QS=3,0;MQSB=0.950498;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,58:2:0 0,18,139:6:0 +X 2099 . G <*> 0 . DP=23;I16=12,10,0,0,719,25109,0,0,1289,76441,0,0,460,10294,0,0;QS=3,0;MQSB=0.947103;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,3,24:1:0 0,18,129:6:0 +X 2100 . C <*> 0 . DP=25;I16=13,11,0,0,873,32759,0,0,1409,83641,0,0,457,10141,0,0;QS=3,0;MQSB=0.950498;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,87:3:0 0,18,160:6:0 +X 2101 . A <*> 0 . DP=25;I16=12,12,0,0,907,34671,0,0,1440,86400,0,0,455,9965,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,135:4:0 0,18,161:6:0 +X 2102 . G <*> 0 . DP=25;I16=13,12,0,0,930,35596,0,0,1469,87241,0,0,478,10442,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,118:4:0 0,18,151:6:0 +X 2103 . C <*> 0 . DP=25;I16=11,12,0,0,842,31630,0,0,1380,82800,0,0,432,9336,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,106:4:0 0,15,146:5:0 +X 2104 . C <*> 0 . DP=24;I16=12,12,0,0,869,32463,0,0,1409,83641,0,0,454,9810,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,126:4:0 0,15,147:5:0 +X 2105 . A <*> 0 . DP=25;I16=11,12,0,0,836,30696,0,0,1380,82800,0,0,429,9201,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,138:4:0 0,15,130:5:0 +X 2106 . T <*> 0 . DP=25;I16=12,13,0,0,897,33087,0,0,1469,87241,0,0,473,10211,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,129:4:0 0,15,146:5:0 +X 2107 . C <*> 0 . DP=25;I16=11,12,0,0,783,27185,0,0,1380,82800,0,0,425,9113,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,100:3:0 0,15,133:5:0 +X 2108 . G <*> 0 . DP=25;I16=11,13,0,0,829,29703,0,0,1440,86400,0,0,448,9730,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,122:4:0 0,15,111:5:0 +X 2109 . C <*> 0 . DP=25;I16=11,13,0,0,781,26717,0,0,1440,86400,0,0,446,9746,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,109:4:0 0,15,125:5:0 +X 2110 . G <*> 0 . DP=25;I16=12,12,0,0,804,28134,0,0,1440,86400,0,0,418,9110,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,92:3:0 0,15,117:5:0 +X 2111 . C <*> 0 . DP=25;I16=12,13,0,0,925,35081,0,0,1500,90000,0,0,441,9747,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,134:4:0 0,15,140:5:0 +X 2112 . A <*> 0 . DP=24;I16=12,12,0,0,885,33445,0,0,1440,86400,0,0,440,9782,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,129:4:0 0,15,140:5:0 +X 2113 . G <*> 0 . DP=24;I16=12,12,0,0,871,32641,0,0,1440,86400,0,0,439,9839,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,128:4:0 0,15,134:5:0 +X 2114 . C <*> 0 . DP=24;I16=12,11,0,0,844,32052,0,0,1380,82800,0,0,413,9293,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,103:3:0 0,15,126:5:0 +X 2115 . T <*> 0 . DP=23;I16=11,11,0,0,821,30869,0,0,1320,79200,0,0,412,9342,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,78:2:0 0,15,143:5:0 +X 2116 . C <*> 0 . DP=23;I16=11,12,0,0,890,34892,0,0,1380,82800,0,0,435,9985,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,102:3:0 0,15,152:5:0 +X 2117 . A <*> 0 . DP=23;I16=11,11,0,0,833,32121,0,0,1320,79200,0,0,432,9924,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,118:3:0 0,15,156:5:0 +X 2118 . G <*> 0 . DP=23;I16=12,11,0,0,842,31502,0,0,1380,82800,0,0,429,9835,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,125:4:0 0,15,147:5:0 +X 2119 . G <*> 0 . DP=23;I16=12,11,0,0,823,30553,0,0,1380,82800,0,0,426,9768,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,135:4:0 0,15,137:5:0 +X 2120 . G <*> 0 . DP=24;I16=13,11,0,0,864,32028,0,0,1440,86400,0,0,423,9723,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,137:4:0 0,15,140:5:0 +X 2121 . A <*> 0 . DP=22;I16=11,10,0,0,734,26712,0,0,1260,75600,0,0,398,9074,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,135:4:0 0,12,122:4:0 +X 2122 . T <*> 0 . DP=22;I16=11,10,0,0,752,27278,0,0,1260,75600,0,0,396,8972,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,136:4:0 0,12,123:4:0 +X 2123 . A <*> 0 . DP=22;I16=12,10,0,0,758,27024,0,0,1320,79200,0,0,419,9519,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,120:4:0 0,15,137:5:0 +X 2124 . T <*> 0 . DP=22;I16=12,10,0,0,789,28741,0,0,1320,79200,0,0,417,9465,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,128:4:0 0,15,136:5:0 +X 2125 . T <*> 0 . DP=20;I16=11,8,0,0,696,25704,0,0,1140,68400,0,0,401,9177,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,106:3:0 0,9,93:3:0 +X 2126 . A <*> 0 . DP=20;I16=11,9,0,0,717,25979,0,0,1200,72000,0,0,415,9319,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,133:4:0 0,9,95:3:0 +X 2127 . C <*> 0 . DP=21;I16=11,10,0,0,706,24426,0,0,1260,75600,0,0,413,9221,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,107:4:0 0,9,95:3:0 +X 2128 . G <*> 0 . DP=21;I16=11,10,0,0,677,22633,0,0,1260,75600,0,0,411,9091,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,116:4:0 0,9,72:3:0 +X 2129 . T <*> 0 . DP=21;I16=11,10,0,0,782,29386,0,0,1260,75600,0,0,409,8981,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,140:4:0 0,9,83:3:0 +X 2130 . G <*> 0 . DP=21;I16=11,10,0,0,766,28562,0,0,1260,75600,0,0,407,8891,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,135:4:0 0,9,87:3:0 +X 2131 . T <*> 0 . DP=21;I16=11,10,0,0,732,26216,0,0,1260,75600,0,0,405,8821,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,136:4:0 0,9,79:3:0 +X 2132 . A <*> 0 . DP=21;I16=11,10,0,0,743,26733,0,0,1260,75600,0,0,403,8771,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,135:4:0 0,9,88:3:0 +X 2133 . A <*> 0 . DP=21;I16=11,10,0,0,787,29651,0,0,1260,75600,0,0,401,8741,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,141:4:0 0,9,96:3:0 +X 2134 . C <*> 0 . DP=21;I16=11,10,0,0,804,31100,0,0,1260,75600,0,0,399,8731,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,138:4:0 0,9,86:3:0 +X 2135 . T <*> 0 . DP=22;I16=11,11,0,0,831,32197,0,0,1320,79200,0,0,397,8741,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,153:4:0 0,12,119:4:0 +X 2136 . C <*> 0 . DP=22;I16=11,11,0,0,760,26892,0,0,1320,79200,0,0,395,8721,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,124:4:0 0,12,127:4:0 +X 2137 . G <*> 0 . DP=22;I16=11,11,0,0,745,26047,0,0,1320,79200,0,0,393,8721,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,121:4:0 0,12,102:4:0 +X 2138 . A <*> 0 . DP=22;I16=11,11,0,0,816,30934,0,0,1320,79200,0,0,391,8741,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,128:4:0 0,12,139:4:0 +X 2139 . C <*> 0 . DP=22;I16=11,11,0,0,839,32237,0,0,1320,79200,0,0,389,8781,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,138:4:0 0,12,125:4:0 +X 2140 . A <*> 0 . DP=22;I16=11,11,0,0,826,31300,0,0,1320,79200,0,0,387,8841,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,140:4:0 0,12,138:4:0 +X 2141 . T <*> 0 . DP=21;I16=11,10,0,0,792,30156,0,0,1260,75600,0,0,385,8871,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,137:4:0 0,12,137:4:0 +X 2142 . G <*> 0 . DP=19;I16=11,8,0,0,724,27784,0,0,1140,68400,0,0,385,8919,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,113:3:0 0,12,129:4:0 +X 2143 . T <*> 0 . DP=19;I16=11,8,0,0,650,23454,0,0,1140,68400,0,0,384,8932,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,113:3:0 0,12,120:4:0 +X 2144 . C <*> 0 . DP=19;I16=11,8,0,0,739,29003,0,0,1140,68400,0,0,383,8959,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,108:3:0 0,12,125:4:0 +X 2145 . A <*> 0 . DP=20;I16=12,8,0,0,760,29304,0,0,1200,72000,0,0,381,8951,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,133:4:0 0,12,139:4:0 +X 2146 . G <*> 0 . DP=20;I16=12,8,0,0,745,28105,0,0,1200,72000,0,0,379,8909,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,139:4:0 0,12,127:4:0 +X 2147 . C <*> 0 . DP=20;I16=13,6,0,0,674,24296,0,0,1140,68400,0,0,379,8881,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,127:4:0 0,12,130:4:0 +X 2148 . G <*> 0 . DP=20;I16=12,7,0,0,630,21274,0,0,1140,68400,0,0,365,8537,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,250:11:0 0,12,112:4:0 0,12,120:4:0 +X 2149 . A <*> 0 . DP=20;I16=12,7,0,0,702,26212,0,0,1140,68400,0,0,367,8529,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,138:4:0 0,12,127:4:0 +X 2150 . T <*> 0 . DP=20;I16=13,7,0,0,675,23943,0,0,1200,72000,0,0,383,8713,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,247:11:0 0,12,138:4:0 0,15,139:5:0 +X 2151 . T <*> 0 . DP=20;I16=13,7,0,0,690,24274,0,0,1200,72000,0,0,383,8661,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,251:11:0 0,12,133:4:0 0,15,142:5:0 +X 2152 . G <*> 0 . DP=20;I16=13,7,0,0,693,24713,0,0,1200,72000,0,0,383,8629,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,131:4:0 0,15,146:5:0 +X 2153 . T <*> 0 . DP=19;I16=13,6,0,0,671,24571,0,0,1140,68400,0,0,383,8565,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,230:10:0 0,12,134:4:0 0,15,162:5:0 +X 2154 . C <*> 0 . DP=19;I16=13,6,0,0,703,26955,0,0,1140,68400,0,0,382,8468,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,251:10:0 0,12,131:4:0 0,15,159:5:0 +X 2155 . A <*> 0 . DP=19;I16=13,6,0,0,693,25727,0,0,1140,68400,0,0,381,8389,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,245:10:0 0,12,135:4:0 0,15,156:5:0 +X 2156 . C <*> 0 . DP=19;I16=13,6,0,0,702,26214,0,0,1140,68400,0,0,380,8328,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,125:4:0 0,15,154:5:0 +X 2157 . A <*> 0 . DP=19;I16=13,6,0,0,722,28058,0,0,1140,68400,0,0,379,8285,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,12,141:4:0 0,15,173:5:0 +X 2158 . G <*> 0 . DP=19;I16=13,6,0,0,713,27567,0,0,1140,68400,0,0,378,8260,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,136:4:0 0,15,144:5:0 +X 2159 . G <*> 0 . DP=19;I16=12,6,0,0,662,24744,0,0,1080,64800,0,0,366,8104,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,247:9:0 0,12,126:4:0 0,15,153:5:0 +X 2160 . C <*> 0 . DP=19;I16=12,6,0,0,651,24005,0,0,1080,64800,0,0,364,8038,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,12,119:4:0 0,15,154:5:0 +X 2161 . A <*> 0 . DP=19;I16=13,6,0,0,695,25883,0,0,1140,68400,0,0,369,8005,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,12,121:4:0 0,15,164:5:0 +X 2162 . C <*> 0 . DP=20;I16=13,7,0,0,742,27834,0,0,1200,72000,0,0,365,7911,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,127:4:0 0,15,155:5:0 +X 2163 . T <*> 0 . DP=20;I16=13,7,0,0,763,29517,0,0,1200,72000,0,0,362,7838,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,131:4:0 0,15,175:5:0 +X 2164 . G <*> 0 . DP=20;I16=13,7,0,0,715,26301,0,0,1200,72000,0,0,359,7787,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,116:4:0 0,15,156:5:0 +X 2165 . C <*> 0 . DP=20;I16=13,7,0,0,753,28781,0,0,1200,72000,0,0,355,7709,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,136:4:0 0,15,151:5:0 +X 2166 . T <*> 0 . DP=19;I16=12,7,0,0,711,27211,0,0,1140,68400,0,0,352,7654,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,142:4:0 0,12,140:4:0 +X 2167 . A <*> 0 . DP=19;I16=12,6,0,0,650,23760,0,0,1080,64800,0,0,327,7137,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,12,133:4:0 0,9,111:3:0 +X 2168 . C <*> 0 . DP=19;I16=12,7,0,0,685,25039,0,0,1140,68400,0,0,345,7561,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,130:4:0 0,12,124:4:0 +X 2169 . T <*> 0 . DP=19;I16=12,7,0,0,702,26940,0,0,1140,68400,0,0,341,7525,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,140:4:0 0,12,142:4:0 +X 2170 . C <*> 0 . DP=18;I16=11,7,0,0,665,24861,0,0,1080,64800,0,0,338,7512,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,132:4:0 0,12,135:4:0 +X 2171 . C <*> 0 . DP=20;I16=11,9,0,0,750,28368,0,0,1200,72000,0,0,333,7419,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,136:4:0 0,12,138:4:0 +X 2172 . T <*> 0 . DP=20;I16=11,9,0,0,732,27540,0,0,1200,72000,0,0,330,7346,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,149:4:0 0,12,147:4:0 +X 2173 . G <*> 0 . DP=19;I16=10,9,0,0,704,26534,0,0,1140,68400,0,0,327,7243,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,142:4:0 0,12,133:4:0 +X 2174 . G <*> 0 . DP=19;I16=10,9,0,0,674,24372,0,0,1140,68400,0,0,324,7158,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,126:4:0 0,12,129:4:0 +X 2175 . G <*> 0 . DP=18;I16=9,9,0,0,639,23059,0,0,1080,64800,0,0,322,7090,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,123:4:0 0,12,126:4:0 +X 2176 . G <*> 0 . DP=18;I16=9,9,0,0,621,21815,0,0,1080,64800,0,0,318,6940,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,12,121:4:0 0,12,123:4:0 +X 2177 . T <*> 0 . DP=18;I16=9,9,0,0,547,18051,0,0,1080,64800,0,0,314,6810,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,239:10:0 0,12,83:4:0 0,12,108:4:0 +X 2178 . T <*> 0 . DP=18;I16=9,9,0,0,579,19659,0,0,1080,64800,0,0,310,6700,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,234:10:0 0,12,110:4:0 0,12,118:4:0 +X 2179 . T <*> 0 . DP=18;I16=9,9,0,0,591,20403,0,0,1080,64800,0,0,307,6609,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,239:10:0 0,12,97:4:0 0,12,135:4:0 +X 2180 . T <*> 0 . DP=18;I16=9,9,0,0,616,21524,0,0,1080,64800,0,0,305,6537,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,236:10:0 0,12,122:4:0 0,12,133:4:0 +X 2181 . C <*> 0 . DP=18;I16=9,8,0,0,611,22485,0,0,1020,61200,0,0,293,6385,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,224:9:0 0,12,129:4:0 0,12,150:4:0 +X 2182 . C <*> 0 . DP=18;I16=9,9,0,0,665,24877,0,0,1080,64800,0,0,301,6453,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,125:4:0 0,12,145:4:0 +X 2183 . A <*> 0 . DP=18;I16=9,9,0,0,646,23624,0,0,1080,64800,0,0,299,6441,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,12,123:4:0 0,12,144:4:0 +X 2184 . T <*> 0 . DP=17;I16=8,9,0,0,610,22250,0,0,1020,61200,0,0,298,6448,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,224:9:0 0,12,134:4:0 0,12,136:4:0 +X 2185 . C <*> 0 . DP=16;I16=8,8,0,0,569,20761,0,0,960,57600,0,0,297,6423,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,211:8:0 0,12,128:4:0 0,12,137:4:0 +X 2186 . A <*> 0 . DP=16;I16=8,8,0,0,576,21314,0,0,960,57600,0,0,296,6416,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,204:8:0 0,12,134:4:0 0,12,145:4:0 +X 2187 . A <*> 0 . DP=16;I16=8,8,0,0,562,20396,0,0,960,57600,0,0,295,6427,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,201:8:0 0,12,136:4:0 0,12,135:4:0 +X 2188 . A <*> 0 . DP=17;I16=9,8,0,0,569,19925,0,0,1020,61200,0,0,293,6405,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,214:9:0 0,12,133:4:0 0,12,123:4:0 +X 2189 . C <*> 0 . DP=19;I16=9,10,0,0,645,22647,0,0,1097,65089,0,0,292,6400,0,0;QS=3,0;MQSB=0.934728;MQ0F=0 PL:DP:DV 0,30,230:10:0 0,12,133:4:0 0,15,142:5:0 +X 2190 . C <*> 0 . DP=19;I16=9,10,0,0,604,20072,0,0,1097,65089,0,0,294,6414,0,0;QS=3,0;MQSB=0.934728;MQ0F=0 PL:DP:DV 0,33,238:11:0 0,12,119:4:0 0,12,107:4:0 +X 2191 . C <*> 0 . DP=19;I16=9,10,0,0,647,23007,0,0,1097,65089,0,0,297,6449,0,0;QS=3,0;MQSB=0.934728;MQ0F=0 PL:DP:DV 0,33,251:11:0 0,12,129:4:0 0,12,119:4:0 +X 2192 . T <*> 0 . DP=19;I16=9,10,0,0,659,23723,0,0,1097,65089,0,0,300,6506,0,0;QS=3,0;MQSB=0.934728;MQ0F=0 PL:DP:DV 0,33,253:11:0 0,12,136:4:0 0,12,120:4:0 +X 2193 . C <*> 0 . DP=18;I16=8,10,0,0,642,23934,0,0,1037,61489,0,0,303,6535,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,128:4:0 0,9,87:3:0 +X 2194 . A <*> 0 . DP=18;I16=8,9,0,0,617,22683,0,0,1020,61200,0,0,301,6561,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,12,134:4:0 0,9,98:3:0 +X 2195 . A <*> 0 . DP=18;I16=8,10,0,0,635,23271,0,0,1037,61489,0,0,309,6659,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,128:4:0 0,9,101:3:0 +X 2196 . G <*> 0 . DP=19;I16=8,11,0,0,703,26383,0,0,1097,65089,0,0,312,6754,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,117:4:0 0,12,120:4:0 +X 2197 . A <*> 0 . DP=19;I16=8,11,0,0,735,28599,0,0,1097,65089,0,0,314,6770,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,141:4:0 0,12,125:4:0 +X 2198 . G <*> 0 . DP=19;I16=8,10,0,0,650,24206,0,0,1080,64800,0,0,307,6725,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,129:4:0 0,12,107:4:0 +X 2199 . C <*> 0 . DP=19;I16=8,11,0,0,701,26735,0,0,1097,65089,0,0,318,6862,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,128:4:0 0,12,116:4:0 +X 2200 . T <*> 0 . DP=19;I16=8,11,0,0,710,26768,0,0,1097,65089,0,0,320,6938,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,129:4:0 0,12,114:4:0 +X 2201 . G <*> 0 . DP=17;I16=7,10,0,0,628,23764,0,0,977,57889,0,0,324,7032,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,66:2:0 0,12,119:4:0 +X 2202 . G <*> 0 . DP=17;I16=7,10,0,0,557,19249,0,0,977,57889,0,0,327,7093,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,33,245:11:0 0,6,57:2:0 0,12,115:4:0 +X 2203 . G <*> 0 . DP=17;I16=7,10,0,0,588,21184,0,0,977,57889,0,0,329,7123,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,47:2:0 0,12,116:4:0 +X 2204 . C <*> 0 . DP=17;I16=7,10,0,0,538,18568,0,0,977,57889,0,0,331,7173,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,33,246:11:0 0,6,61:2:0 0,12,99:4:0 +X 2205 . C <*> 0 . DP=18;I16=7,11,0,0,628,22918,0,0,1037,61489,0,0,332,7192,0,0;QS=3,0;MQSB=0.951002;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,68:2:0 0,12,109:4:0 +X 2206 . T <*> 0 . DP=19;I16=7,12,0,0,677,25237,0,0,1097,65089,0,0,334,7230,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,77:2:0 0,12,115:4:0 +X 2207 . G <*> 0 . DP=19;I16=7,11,0,0,663,24717,0,0,1080,64800,0,0,319,6965,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,67:2:0 0,12,110:4:0 +X 2208 . G <*> 0 . DP=21;I16=7,14,0,0,726,26038,0,0,1217,72289,0,0,340,7370,0,0;QS=3,0;MQSB=0.966484;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,110:4:0 0,12,122:4:0 +X 2209 . G <*> 0 . DP=22;I16=8,13,0,0,715,25133,0,0,1237,73369,0,0,325,7075,0,0;QS=3,0;MQSB=0.895122;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,128:5:0 0,12,117:4:0 +X 2210 . G C,<*> 0 . DP=21;I16=7,13,0,1,648,22186,25,625,1177,69769,17,289,331,7165,21,441;QS=2.95442,0.0455764,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.975265;BQB=1;MQ0F=0 PL:DP:DV 0,19,234,33,237,241:12:1 0,15,127,15,127,127:5:0 0,12,113,12,113,113:4:0 +X 2211 . T <*> 0 . DP=21;I16=7,13,0,0,724,27000,0,0,1177,69769,0,0,336,7230,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,141:5:0 0,12,124:4:0 +X 2212 . C <*> 0 . DP=22;I16=8,14,0,0,791,29201,0,0,1254,73658,0,0,364,7850,0,0;QS=3,0;MQSB=0.985548;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,148:5:0 0,12,111:4:0 +X 2213 . A <*> 0 . DP=22;I16=8,14,0,0,767,27327,0,0,1254,73658,0,0,371,8015,0,0;QS=3,0;MQSB=0.985548;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,153:5:0 0,12,112:4:0 +X 2214 . A <*> 0 . DP=22;I16=8,14,0,0,756,26836,0,0,1254,73658,0,0,377,8159,0,0;QS=3,0;MQSB=0.985548;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,153:5:0 0,12,117:4:0 +X 2215 . C <*> 0 . DP=22;I16=8,14,0,0,815,31121,0,0,1254,73658,0,0,381,8229,0,0;QS=3,0;MQSB=0.985548;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,162:5:0 0,12,124:4:0 +X 2216 . T <*> 0 . DP=22;I16=8,14,0,0,815,31233,0,0,1254,73658,0,0,384,8272,0,0;QS=3,0;MQSB=0.985548;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,166:5:0 0,12,124:4:0 +X 2217 . T <*> 0 . DP=22;I16=8,13,0,0,741,26855,0,0,1237,73369,0,0,362,7712,0,0;QS=3,0;MQSB=0.895122;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,155:5:0 0,12,118:4:0 +X 2218 . C <*> 0 . DP=21;I16=7,14,0,0,753,27973,0,0,1194,70058,0,0,391,8423,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,138:4:0 0,12,119:4:0 +X 2219 . C <*> 0 . DP=21;I16=7,13,0,0,757,29125,0,0,1177,69769,0,0,370,7904,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,141:4:0 0,12,122:4:0 +X 2220 . G A,<*> 0 . DP=21;I16=6,2,1,11,256,8364,474,19128,457,26569,720,43200,141,2959,233,5071;QS=0.886504,2.1135,0;VDB=0.532753;SGB=-3.51597;RPB=0.964198;MQB=0.898397;MQSB=0.875769;BQB=0.0354359;MQ0F=0 PL:DP:DV 139,0,130,157,148,255:12:6 69,0,46,75,52,119:4:2 131,12,0,131,12,131:4:4 +X 2221 . G <*> 0 . DP=21;I16=7,13,0,0,738,27922,0,0,1177,69769,0,0,376,8078,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,132:4:0 0,12,120:4:0 +X 2222 . C <*> 0 . DP=21;I16=7,14,0,0,746,28098,0,0,1194,70058,0,0,401,8675,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,135:4:0 0,12,107:4:0 +X 2223 . C <*> 0 . DP=21;I16=7,14,0,0,796,30632,0,0,1194,70058,0,0,401,8671,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,135:4:0 0,12,122:4:0 +X 2224 . T <*> 0 . DP=21;I16=7,14,0,0,811,31599,0,0,1194,70058,0,0,401,8691,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,144:4:0 0,12,123:4:0 +X 2225 . G <*> 0 . DP=21;I16=7,14,0,0,778,29396,0,0,1194,70058,0,0,401,8735,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,133:4:0 0,12,121:4:0 +X 2226 . G <*> 0 . DP=21;I16=7,14,0,0,727,26485,0,0,1194,70058,0,0,401,8803,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,128:4:0 0,12,113:4:0 +X 2227 . G <*> 0 . DP=20;I16=7,12,0,0,663,23985,0,0,1117,66169,0,0,377,8269,0,0;QS=3,0;MQSB=0.879351;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,123:4:0 0,12,114:4:0 +X 2228 . G C,<*> 0 . DP=19;I16=5,12,0,1,643,24791,16,256,1020,61200,17,289,360,8020,25,625;QS=2.9603,0.0397022,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.970092;BQB=1;MQ0F=0 PL:DP:DV 0,17,255,30,255,255:11:1 0,9,95,9,95,95:3:0 0,12,121,12,121,121:4:0 +X 2229 . A <*> 0 . DP=20;I16=6,14,0,0,757,28857,0,0,1134,66458,0,0,406,9138,0,0;QS=3,0;MQSB=0.959189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,138:4:0 0,12,122:4:0 +X 2230 . A <*> 0 . DP=20;I16=6,14,0,0,729,26985,0,0,1134,66458,0,0,409,9291,0,0;QS=3,0;MQSB=0.959189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,141:4:0 0,12,119:4:0 +X 2231 . A <*> 0 . DP=20;I16=6,13,0,0,712,26990,0,0,1117,66169,0,0,386,8790,0,0;QS=3,0;MQSB=0.850016;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,144:4:0 0,12,124:4:0 +X 2232 . C <*> 0 . DP=20;I16=6,14,0,0,751,28657,0,0,1134,66458,0,0,412,9508,0,0;QS=3,0;MQSB=0.959189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,130:4:0 0,12,107:4:0 +X 2233 . T <*> 0 . DP=20;I16=6,14,0,0,774,30432,0,0,1134,66458,0,0,413,9619,0,0;QS=3,0;MQSB=0.959189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,150:4:0 0,12,117:4:0 +X 2234 . G <*> 0 . DP=20;I16=6,14,0,0,719,26621,0,0,1134,66458,0,0,412,9646,0,0;QS=3,0;MQSB=0.959189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,145:4:0 0,12,107:4:0 +X 2235 . G <*> 0 . DP=20;I16=6,14,0,0,728,27036,0,0,1134,66458,0,0,410,9636,0,0;QS=3,0;MQSB=0.959189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,139:4:0 0,12,104:4:0 +X 2236 . G <*> 0 . DP=19;I16=6,13,0,0,705,26985,0,0,1074,62858,0,0,409,9637,0,0;QS=3,0;MQSB=0.965977;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,142:4:0 0,9,84:3:0 +X 2237 . G <*> 0 . DP=19;I16=6,12,0,0,684,26576,0,0,1057,62569,0,0,383,9023,0,0;QS=3,0;MQSB=0.85394;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,141:4:0 0,9,86:3:0 +X 2238 . C <*> 0 . DP=19;I16=5,13,0,0,648,24496,0,0,1037,61489,0,0,381,8993,0,0;QS=3,0;MQSB=0.970092;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,108:3:0 0,9,78:3:0 +X 2239 . A <*> 0 . DP=19;I16=6,11,0,0,634,24178,0,0,997,58969,0,0,373,8935,0,0;QS=3,0;MQSB=0.85832;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,133:4:0 0,6,77:2:0 +X 2240 . A <*> 0 . DP=19;I16=6,13,0,0,731,28595,0,0,1074,62858,0,0,402,9582,0,0;QS=3,0;MQSB=0.965977;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,135:4:0 0,9,101:3:0 +X 2241 . G <*> 0 . DP=19;I16=6,12,0,0,683,26433,0,0,1057,62569,0,0,375,8951,0,0;QS=3,0;MQSB=0.85394;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,126:4:0 0,9,88:3:0 +X 2242 . T <*> 0 . DP=20;I16=5,13,0,0,635,22949,0,0,1057,62569,0,0,370,8944,0,0;QS=3,0;MQSB=0.814433;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,91:3:0 0,9,95:3:0 +X 2243 . A <*> 0 . DP=19;I16=5,14,0,0,704,26274,0,0,1074,62858,0,0,395,9585,0,0;QS=3,0;MQSB=0.933727;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,107:3:0 0,9,99:3:0 +X 2244 . T <*> 0 . DP=19;I16=5,14,0,0,681,25263,0,0,1074,62858,0,0,395,9609,0,0;QS=3,0;MQSB=0.933727;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,89:3:0 0,9,98:3:0 +X 2245 . C <*> 0 . DP=19;I16=5,14,0,0,722,27846,0,0,1074,62858,0,0,394,9592,0,0;QS=3,0;MQSB=0.933727;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,98:3:0 0,9,88:3:0 +X 2246 . A <*> 0 . DP=18;I16=5,12,0,0,597,21693,0,0,997,58969,0,0,367,8861,0,0;QS=3,0;MQSB=0.818731;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,95:3:0 0,6,72:2:0 +X 2247 . C <*> 0 . DP=17;I16=4,13,0,0,639,24373,0,0,954,55658,0,0,391,9391,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,105:3:0 0,6,71:2:0 +X 2248 . C <*> 0 . DP=17;I16=4,13,0,0,669,26863,0,0,954,55658,0,0,390,9306,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,90:3:0 0,6,75:2:0 +X 2249 . A <*> 0 . DP=17;I16=4,13,0,0,677,27371,0,0,954,55658,0,0,389,9231,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,116:3:0 0,6,80:2:0 +X 2250 . G <*> 0 . DP=17;I16=4,13,0,0,654,25800,0,0,954,55658,0,0,388,9166,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,100:3:0 0,6,78:2:0 +X 2251 . A <*> 0 . DP=17;I16=4,13,0,0,673,27327,0,0,954,55658,0,0,387,9111,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,112:3:0 0,6,80:2:0 +X 2252 . G <*> 0 . DP=17;I16=4,12,0,0,647,26249,0,0,937,55369,0,0,361,8441,0,0;QS=3,0;MQSB=0.767432;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,113:3:0 0,6,73:2:0 +X 2253 . A <*> 0 . DP=17;I16=4,13,0,0,641,24643,0,0,954,55658,0,0,385,9031,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,111:3:0 0,6,73:2:0 +X 2254 . T <*> 0 . DP=17;I16=4,12,0,0,615,23821,0,0,937,55369,0,0,358,8332,0,0;QS=3,0;MQSB=0.767432;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,112:3:0 0,6,73:2:0 +X 2255 . G <*> 0 . DP=17;I16=4,13,0,0,677,27243,0,0,954,55658,0,0,380,8844,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,115:3:0 0,6,71:2:0 +X 2256 . A <*> 0 . DP=17;I16=4,13,0,0,656,26088,0,0,954,55658,0,0,377,8741,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,110:3:0 0,6,78:2:0 +X 2257 . G <*> 0 . DP=17;I16=4,12,0,0,627,24863,0,0,937,55369,0,0,349,8023,0,0;QS=3,0;MQSB=0.767432;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,115:3:0 0,6,74:2:0 +X 2258 . C <*> 0 . DP=17;I16=4,13,0,0,667,26403,0,0,954,55658,0,0,371,8565,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,109:3:0 0,6,70:2:0 +X 2259 . T <*> 0 . DP=17;I16=4,13,0,0,646,25334,0,0,954,55658,0,0,368,8492,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,116:3:0 0,6,79:2:0 +X 2260 . T <*> 0 . DP=17;I16=4,13,0,0,638,24178,0,0,954,55658,0,0,365,8429,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,115:3:0 0,6,72:2:0 +X 2261 . T <*> 0 . DP=17;I16=4,13,0,0,633,23799,0,0,954,55658,0,0,362,8376,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,105:3:0 0,6,73:2:0 +X 2262 . A <*> 0 . DP=17;I16=4,13,0,0,628,23438,0,0,954,55658,0,0,359,8333,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,253:12:0 0,9,112:3:0 0,6,74:2:0 +X 2263 . T <*> 0 . DP=17;I16=4,13,0,0,631,23673,0,0,954,55658,0,0,355,8251,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,112:3:0 0,6,74:2:0 +X 2264 . A <*> 0 . DP=17;I16=4,12,0,0,623,24371,0,0,937,55369,0,0,326,7556,0,0;QS=3,0;MQSB=0.767432;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,114:3:0 0,6,75:2:0 +X 2265 . A <*> 0 . DP=18;I16=4,13,0,0,642,24718,0,0,997,58969,0,0,320,7400,0,0;QS=3,0;MQSB=0.762744;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,113:3:0 0,6,75:2:0 +X 2266 . A <*> 0 . DP=19;I16=5,14,0,0,656,23962,0,0,1074,62858,0,0,337,7745,0,0;QS=3,0;MQSB=0.933727;MQ0F=0 PL:DP:DV 0,39,252:13:0 0,12,128:4:0 0,6,75:2:0 +X 2267 . A <*> 0 . DP=20;I16=6,14,0,0,712,26052,0,0,1134,66458,0,0,332,7582,0,0;QS=3,0;MQSB=0.959189;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,134:4:0 0,9,102:3:0 +X 2268 . A <*> 0 . DP=20;I16=6,14,0,0,741,27841,0,0,1134,66458,0,0,327,7391,0,0;QS=3,0;MQSB=0.959189;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,135:4:0 0,9,100:3:0 +X 2269 . T <*> 0 . DP=20;I16=6,13,0,0,681,24751,0,0,1074,62858,0,0,318,7206,0,0;QS=3,0;MQSB=0.965977;MQ0F=0 PL:DP:DV 0,36,246:12:0 0,12,137:4:0 0,9,111:3:0 +X 2270 . A <*> 0 . DP=19;I16=6,12,0,0,652,24154,0,0,1057,62569,0,0,300,6750,0,0;QS=3,0;MQSB=0.85394;MQ0F=0 PL:DP:DV 0,33,244:11:0 0,12,134:4:0 0,9,112:3:0 +X 2271 . A <*> 0 . DP=17;I16=6,11,0,0,654,25406,0,0,954,55658,0,0,316,6944,0,0;QS=3,0;MQSB=0.980001;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,12,142:4:0 0,9,111:3:0 +X 2272 . T <*> 0 . DP=17;I16=6,10,0,0,604,22908,0,0,937,55369,0,0,297,6525,0,0;QS=3,0;MQSB=0.863243;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,12,137:4:0 0,9,111:3:0 +X 2273 . G <*> 0 . DP=17;I16=6,10,0,0,581,22129,0,0,937,55369,0,0,295,6411,0,0;QS=3,0;MQSB=0.863243;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,12,123:4:0 0,9,115:3:0 +X 2274 . G <*> 0 . DP=18;I16=6,11,0,0,621,23109,0,0,997,58969,0,0,293,6313,0,0;QS=3,0;MQSB=0.85832;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,12,132:4:0 0,9,110:3:0 +X 2275 . T <*> 0 . DP=18;I16=6,11,0,0,624,23152,0,0,997,58969,0,0,292,6232,0,0;QS=3,0;MQSB=0.85832;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,12,126:4:0 0,9,113:3:0 +X 2276 . G <*> 0 . DP=20;I16=7,12,0,0,710,26848,0,0,1074,62858,0,0,303,6313,0,0;QS=3,0;MQSB=0.985816;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,129:4:0 0,9,110:3:0 +X 2277 . C <*> 0 . DP=21;I16=8,13,0,0,797,30699,0,0,1194,70058,0,0,303,6247,0,0;QS=3,0;MQSB=0.989565;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,151:5:0 0,12,143:4:0 +X 2278 . T <*> 0 . DP=21;I16=7,13,0,0,736,27790,0,0,1157,68689,0,0,279,5581,0,0;QS=3,0;MQSB=0.962269;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,133:4:0 0,12,148:4:0 +X 2279 . A <*> 0 . DP=20;I16=8,12,0,0,723,27047,0,0,1134,66458,0,0,306,6190,0,0;QS=3,0;MQSB=0.993326;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,155:5:0 0,12,144:4:0 +X 2280 . G <*> 0 . DP=21;I16=8,12,0,0,766,29776,0,0,1177,69769,0,0,299,6085,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,166:5:0 0,12,144:4:0 +X 2281 . C <*> 0 . DP=22;I16=8,13,0,0,784,29748,0,0,1237,73369,0,0,301,6037,0,0;QS=3,0;MQSB=0.895122;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,165:5:0 0,12,140:4:0 +X 2282 . T <*> 0 . DP=22;I16=8,14,0,0,789,29699,0,0,1254,73658,0,0,310,6054,0,0;QS=3,0;MQSB=0.985548;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,162:5:0 0,12,150:4:0 +X 2283 . G <*> 0 . DP=22;I16=8,14,0,0,798,29774,0,0,1254,73658,0,0,312,6054,0,0;QS=3,0;MQSB=0.985548;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,158:5:0 0,12,142:4:0 +X 2284 . G <*> 0 . DP=22;I16=7,14,0,0,760,28408,0,0,1194,70058,0,0,294,5664,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,130:4:0 0,12,141:4:0 +X 2285 . G <*> 0 . DP=23;I16=9,14,0,0,844,31592,0,0,1314,77258,0,0,311,5909,0,0;QS=3,0;MQSB=0.992095;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,152:5:0 0,12,144:4:0 +X 2286 . C <*> 0 . DP=23;I16=9,14,0,0,854,32244,0,0,1314,77258,0,0,311,5869,0,0;QS=3,0;MQSB=0.992095;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,155:5:0 0,12,130:4:0 +X 2287 . A <*> 0 . DP=23;I16=9,14,0,0,818,30288,0,0,1314,77258,0,0,311,5869,0,0;QS=3,0;MQSB=0.992095;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,166:5:0 0,12,143:4:0 +X 2288 . T <*> 0 . DP=22;I16=8,14,0,0,794,29190,0,0,1254,73658,0,0,312,5908,0,0;QS=3,0;MQSB=0.985548;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,158:5:0 0,12,142:4:0 +X 2289 . G <*> 0 . DP=21;I16=8,13,0,0,723,25835,0,0,1237,73369,0,0,314,5984,0,0;QS=3,0;MQSB=0.895122;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,154:5:0 0,12,126:4:0 +X 2290 . G <*> 0 . DP=20;I16=7,13,0,0,748,28318,0,0,1177,69769,0,0,318,6094,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,149:5:0 0,9,114:3:0 +X 2291 . T <*> 0 . DP=20;I16=7,13,0,0,731,27165,0,0,1177,69769,0,0,322,6186,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,151:5:0 0,9,112:3:0 +X 2292 . G <*> 0 . DP=20;I16=7,13,0,0,749,28747,0,0,1177,69769,0,0,325,6259,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,156:5:0 0,9,109:3:0 +X 2293 . G <*> 0 . DP=20;I16=7,13,0,0,739,27903,0,0,1177,69769,0,0,327,6311,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,156:5:0 0,9,112:3:0 +X 2294 . C <*> 0 . DP=21;I16=7,14,0,0,775,29453,0,0,1237,73369,0,0,329,6391,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,169:5:0 0,9,114:3:0 +X 2295 . T <*> 0 . DP=21;I16=7,14,0,0,773,29209,0,0,1237,73369,0,0,331,6451,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,164:5:0 0,9,115:3:0 +X 2296 . T <*> 0 . DP=21;I16=7,14,0,0,756,27780,0,0,1237,73369,0,0,333,6543,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,160:5:0 0,9,106:3:0 +X 2297 . G <*> 0 . DP=20;I16=7,13,0,0,736,27692,0,0,1177,69769,0,0,336,6666,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,165:5:0 0,6,74:2:0 +X 2298 . C <*> 0 . DP=21;I16=7,14,0,0,778,29300,0,0,1237,73369,0,0,339,6819,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,139:5:0 0,9,106:3:0 +X 2299 . A <*> 0 . DP=21;I16=7,14,0,0,714,25282,0,0,1237,73369,0,0,343,7003,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,128:5:0 0,9,110:3:0 +X 2300 . C <*> 0 . DP=21;I16=7,13,0,0,687,24749,0,0,1177,69769,0,0,326,6768,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,148:5:0 0,9,109:3:0 +X 2301 . C <*> 0 . DP=23;I16=7,15,0,0,802,30292,0,0,1266,74210,0,0,349,7363,0,0;QS=3,0;MQSB=0.970024;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,147:5:0 0,9,116:3:0 +X 2302 . T <*> 0 . DP=23;I16=7,16,0,0,860,32956,0,0,1326,77810,0,0,354,7496,0,0;QS=3,0;MQSB=0.964916;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,166:5:0 0,12,150:4:0 +X 2303 . G <*> 0 . DP=23;I16=7,16,0,0,817,29823,0,0,1326,77810,0,0,356,7604,0,0;QS=3,0;MQSB=0.964916;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,151:5:0 0,12,139:4:0 +X 2304 . T <*> 0 . DP=23;I16=7,16,0,0,802,28628,0,0,1326,77810,0,0,357,7691,0,0;QS=3,0;MQSB=0.964916;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,148:5:0 0,12,140:4:0 +X 2305 . A <*> 0 . DP=22;I16=7,14,0,0,725,25585,0,0,1237,73369,0,0,355,7791,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,36,248:12:0 0,15,155:5:0 0,12,129:4:0 +X 2306 . A <*> 0 . DP=21;I16=7,14,0,0,727,26841,0,0,1206,70610,0,0,361,7899,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,36,246:12:0 0,15,168:5:0 0,12,130:4:0 +X 2307 . T <*> 0 . DP=21;I16=7,14,0,0,751,27427,0,0,1206,70610,0,0,362,7964,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,36,251:12:0 0,15,165:5:0 0,12,141:4:0 +X 2308 . C <*> 0 . DP=21;I16=7,14,0,0,735,26675,0,0,1206,70610,0,0,363,8051,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,144:5:0 0,12,146:4:0 +X 2309 . C A,<*> 0 . DP=19;I16=7,11,0,1,604,21364,16,256,1057,62569,29,841,358,8094,8,64;QS=2.95676,0.0432432,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.985816;BQB=1;MQ0F=0 PL:DP:DV 0,20,224,33,227,230:12:1 0,9,94,9,94,94:3:0 0,12,138,12,138,138:4:0 +X 2310 . C <*> 0 . DP=18;I16=6,12,0,0,668,25392,0,0,1049,62041,0,0,370,8282,0,0;QS=3,0;MQSB=0.961295;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,80:2:0 0,12,139:4:0 +X 2311 . A <*> 0 . DP=19;I16=7,12,0,0,707,26855,0,0,1109,65641,0,0,373,8371,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,78:2:0 0,12,137:4:0 +X 2312 . G <*> 0 . DP=20;I16=7,12,0,0,736,29118,0,0,1109,65641,0,0,364,8306,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,82:2:0 0,9,122:3:0 +X 2313 . C <*> 0 . DP=20;I16=7,13,0,0,723,27231,0,0,1169,69241,0,0,382,8596,0,0;QS=3,0;MQSB=0.962269;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,76:2:0 0,12,130:4:0 +X 2314 . A <*> 0 . DP=21;I16=7,12,0,0,630,22184,0,0,1109,65641,0,0,372,8510,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,78:2:0 0,9,115:3:0 +X 2315 . C <*> 0 . DP=23;I16=7,14,0,0,739,26861,0,0,1229,72841,0,0,392,8892,0,0;QS=3,0;MQSB=0.966484;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,71:2:0 0,12,135:4:0 +X 2316 . T <*> 0 . DP=23;I16=8,15,0,0,826,30690,0,0,1349,80041,0,0,408,9102,0,0;QS=3,0;MQSB=0.967216;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,105:3:0 0,15,170:5:0 +X 2317 . T <*> 0 . DP=24;I16=7,16,0,0,766,27014,0,0,1349,80041,0,0,411,9211,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,78:2:0 0,15,170:5:0 +X 2318 . T <*> 0 . DP=24;I16=8,14,0,0,757,27433,0,0,1320,79200,0,0,379,8449,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,91:3:0 0,15,165:5:0 +X 2319 . G <*> 0 . DP=24;I16=6,16,0,0,827,31577,0,0,1289,76441,0,0,398,8882,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,43:1:0 0,15,167:5:0 +X 2320 . G <*> 0 . DP=23;I16=7,16,0,0,803,29077,0,0,1349,80041,0,0,435,9675,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,87:3:0 0,15,157:5:0 +X 2321 . G <*> 0 . DP=23;I16=7,16,0,0,804,29368,0,0,1349,80041,0,0,442,9840,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,79:3:0 0,15,169:5:0 +X 2322 . A <*> 0 . DP=24;I16=7,17,0,0,860,32116,0,0,1409,83641,0,0,449,10027,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,95:3:0 0,15,178:5:0 +X 2323 . G <*> 0 . DP=24;I16=7,17,0,0,863,31887,0,0,1409,83641,0,0,457,10237,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,88:3:0 0,15,153:5:0 +X 2324 . G <*> 0 . DP=24;I16=7,16,0,0,786,27932,0,0,1349,80041,0,0,462,10416,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,88:3:0 0,15,161:5:0 +X 2325 . C <*> 0 . DP=24;I16=7,15,0,0,730,25576,0,0,1289,76441,0,0,427,9625,0,0;QS=3,0;MQSB=0.970024;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,102:3:0 0,12,130:4:0 +X 2326 . C <*> 0 . DP=24;I16=7,15,0,0,709,23523,0,0,1320,79200,0,0,426,9498,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,241:15:0 0,9,95:3:0 0,12,133:4:0 +X 2327 . G <*> 0 . DP=24;I16=7,17,0,0,817,29275,0,0,1409,83641,0,0,481,10891,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,81:3:0 0,15,158:5:0 +X 2328 . A <*> 0 . DP=24;I16=6,17,0,0,814,29804,0,0,1349,80041,0,0,461,10427,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,82:3:0 0,15,172:5:0 +X 2329 . G <*> 0 . DP=23;I16=6,16,0,0,755,27641,0,0,1289,76441,0,0,477,11005,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,63:2:0 0,15,160:5:0 +X 2330 . C <*> 0 . DP=24;I16=7,17,0,0,875,33131,0,0,1409,83641,0,0,498,11424,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,87:3:0 0,18,181:6:0 +X 2331 . T <*> 0 . DP=24;I16=7,17,0,0,862,31882,0,0,1409,83641,0,0,505,11635,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,106:3:0 0,18,200:6:0 +X 2332 . A <*> 0 . DP=25;I16=8,17,0,0,926,35412,0,0,1469,87241,0,0,512,11864,0,0;QS=3,0;MQSB=0.973216;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,97:3:0 0,18,204:6:0 +X 2333 . G <*> 0 . DP=26;I16=8,17,0,0,923,35129,0,0,1469,87241,0,0,494,11436,0,0;QS=3,0;MQSB=0.973216;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,97:3:0 0,18,189:6:0 +X 2334 . G <*> 0 . DP=26;I16=8,18,0,0,928,34574,0,0,1529,90841,0,0,527,12277,0,0;QS=3,0;MQSB=0.975611;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,93:3:0 0,21,202:7:0 +X 2335 . A <*> 0 . DP=26;I16=8,18,0,0,967,36793,0,0,1529,90841,0,0,535,12513,0,0;QS=3,0;MQSB=0.975611;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,105:3:0 0,21,214:7:0 +X 2336 . G <*> 0 . DP=26;I16=8,18,0,0,962,36346,0,0,1529,90841,0,0,543,12769,0,0;QS=3,0;MQSB=0.975611;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,92:3:0 0,21,204:7:0 +X 2337 . G <*> 0 . DP=26;I16=7,18,0,0,895,32981,0,0,1469,87241,0,0,527,12465,0,0;QS=3,0;MQSB=0.977814;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,74:2:0 0,21,204:7:0 +X 2338 . A <*> 0 . DP=26;I16=8,18,0,0,892,31758,0,0,1529,90841,0,0,556,13186,0,0;QS=3,0;MQSB=0.975611;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,87:3:0 0,21,194:7:0 +X 2339 . T <*> 0 . DP=26;I16=7,18,0,0,827,28921,0,0,1469,87241,0,0,537,12769,0,0;QS=3,0;MQSB=0.977814;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,55:2:0 0,21,200:7:0 +X 2340 . C <*> 0 . DP=25;I16=7,18,0,0,792,25816,0,0,1469,87241,0,0,541,12893,0,0;QS=3,0;MQSB=0.977814;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,57:2:0 0,21,173:7:0 +X 2341 . G <*> 0 . DP=25;I16=6,17,0,0,771,26477,0,0,1349,80041,0,0,494,11732,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,3,41:1:0 0,21,186:7:0 +X 2342 . T <*> 0 . DP=24;I16=6,17,0,0,863,32711,0,0,1349,80041,0,0,523,12459,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,3,43:1:0 0,21,214:7:0 +X 2343 . T <*> 0 . DP=24;I16=6,16,0,0,770,28230,0,0,1289,76441,0,0,504,12032,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,44:1:0 0,21,213:7:0 +X 2344 . T <*> 0 . DP=24;I16=7,17,0,0,843,30483,0,0,1409,83641,0,0,552,13124,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,56:2:0 0,21,202:7:0 +X 2345 . G <*> 0 . DP=24;I16=7,17,0,0,897,34121,0,0,1409,83641,0,0,554,13162,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,77:2:0 0,21,206:7:0 +X 2346 . A <*> 0 . DP=24;I16=7,17,0,0,908,34818,0,0,1409,83641,0,0,556,13212,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,68:2:0 0,21,220:7:0 +X 2347 . G <*> 0 . DP=24;I16=6,17,0,0,824,30406,0,0,1349,80041,0,0,533,12649,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,3,39:1:0 0,21,190:7:0 +X 2348 . T <*> 0 . DP=24;I16=7,16,0,0,745,25653,0,0,1349,80041,0,0,544,13072,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,64:2:0 0,18,183:6:0 +X 2349 . C <*> 0 . DP=24;I16=6,17,0,0,804,29224,0,0,1349,80041,0,0,534,12656,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,3,36:1:0 0,21,200:7:0 +X 2350 . C <*> 0 . DP=25;I16=7,17,0,0,869,31905,0,0,1409,83641,0,0,534,12652,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,63:2:0 0,21,198:7:0 +X 2351 . A <*> 0 . DP=25;I16=8,17,0,0,945,36169,0,0,1469,87241,0,0,559,13237,0,0;QS=3,0;MQSB=0.973216;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,74:2:0 0,21,222:7:0 +X 2352 . G <*> 0 . DP=25;I16=7,17,0,0,893,34005,0,0,1409,83641,0,0,533,12539,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,41:1:0 0,21,207:7:0 +X 2353 . C <*> 0 . DP=24;I16=7,17,0,0,866,31864,0,0,1409,83641,0,0,531,12435,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,41:1:0 0,21,205:7:0 +X 2354 . A <*> 0 . DP=24;I16=7,17,0,0,880,33206,0,0,1409,83641,0,0,529,12351,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,43:1:0 0,21,214:7:0 +X 2355 . G <*> 0 . DP=24;I16=7,17,0,0,871,32261,0,0,1409,83641,0,0,526,12238,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,39:1:0 0,21,195:7:0 +X 2356 . T <*> 0 . DP=24;I16=7,17,0,0,887,33305,0,0,1409,83641,0,0,521,12047,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,43:1:0 0,21,219:7:0 +X 2357 . T <*> 0 . DP=24;I16=7,17,0,0,899,34225,0,0,1409,83641,0,0,516,11878,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,43:1:0 0,21,220:7:0 +X 2358 . T <*> 0 . DP=24;I16=7,17,0,0,913,34891,0,0,1409,83641,0,0,510,11680,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,40:1:0 0,21,218:7:0 +X 2359 . G <*> 0 . DP=25;I16=7,17,0,0,898,34048,0,0,1409,83641,0,0,503,11451,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,39:1:0 0,21,209:7:0 +X 2360 . A <*> 0 . DP=25;I16=7,18,0,0,959,37113,0,0,1469,87241,0,0,514,11552,0,0;QS=3,0;MQSB=0.977814;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,72:2:0 0,21,222:7:0 +X 2361 . G <*> 0 . DP=25;I16=7,17,0,0,850,30946,0,0,1409,83641,0,0,482,10726,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,67:2:0 0,18,168:6:0 +X 2362 . A <*> 0 . DP=25;I16=7,17,0,0,762,25482,0,0,1409,83641,0,0,475,10547,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,51:2:0 0,18,159:6:0 +X 2363 . C <*> 0 . DP=25;I16=7,18,0,0,875,31837,0,0,1469,87241,0,0,493,11015,0,0;QS=3,0;MQSB=0.977814;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,65:2:0 0,21,187:7:0 +X 2364 . C <*> 0 . DP=25;I16=7,18,0,0,927,34965,0,0,1469,87241,0,0,486,10880,0,0;QS=3,0;MQSB=0.977814;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,64:2:0 0,21,201:7:0 +X 2365 . A <*> 0 . DP=24;I16=7,17,0,0,908,34754,0,0,1409,83641,0,0,479,10717,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,65:2:0 0,21,221:7:0 +X 2366 . G <*> 0 . DP=25;I16=7,17,0,0,912,35074,0,0,1440,86400,0,0,447,9951,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,58:2:0 0,21,206:7:0 +X 2367 . C <*> 0 . DP=25;I16=7,17,0,0,872,32088,0,0,1409,83641,0,0,440,9782,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,36:1:0 0,21,197:7:0 +X 2368 . C <*> 0 . DP=24;I16=6,17,0,0,871,33801,0,0,1349,80041,0,0,434,9634,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,39:1:0 0,18,180:6:0 +X 2369 . T <*> 0 . DP=24;I16=6,18,0,0,877,33009,0,0,1409,83641,0,0,452,10082,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,49:2:0 0,18,179:6:0 +X 2370 . G <*> 0 . DP=24;I16=6,18,0,0,899,34289,0,0,1409,83641,0,0,445,9927,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,56:2:0 0,18,179:6:0 +X 2371 . G <*> 0 . DP=24;I16=6,18,0,0,880,33088,0,0,1409,83641,0,0,438,9794,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,51:2:0 0,18,177:6:0 +X 2372 . C <*> 0 . DP=24;I16=6,18,0,0,827,29615,0,0,1409,83641,0,0,431,9683,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,47:2:0 0,18,163:6:0 +X 2373 . C <*> 0 . DP=24;I16=6,18,0,0,886,33212,0,0,1409,83641,0,0,424,9594,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,58:2:0 0,18,166:6:0 +X 2374 . A <*> 0 . DP=23;I16=6,17,0,0,844,31230,0,0,1349,80041,0,0,417,9477,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,66:2:0 0,18,177:6:0 +X 2375 . A <*> 0 . DP=23;I16=5,17,0,0,788,28340,0,0,1289,76441,0,0,409,9333,0,0;QS=3,0;MQSB=0.981001;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,64:2:0 0,18,171:6:0 +X 2376 . T <*> 0 . DP=22;I16=5,17,0,0,778,27804,0,0,1289,76441,0,0,401,9161,0,0;QS=3,0;MQSB=0.981001;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,62:2:0 0,18,162:6:0 +X 2377 . A <*> 0 . DP=21;I16=4,17,0,0,704,24488,0,0,1229,72841,0,0,394,9008,0,0;QS=3,0;MQSB=0.984085;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,49:2:0 0,15,135:5:0 +X 2378 . C <*> 0 . DP=20;I16=4,16,0,0,626,20138,0,0,1169,69241,0,0,388,8872,0,0;QS=3,0;MQSB=0.982301;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,15:1:0 0,15,108:5:0 +X 2379 . G <*> 0 . DP=20;I16=4,16,0,0,714,25924,0,0,1169,69241,0,0,382,8752,0,0;QS=3,0;MQSB=0.982301;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,34:1:0 0,15,140:5:0 +X 2380 . G <*> 0 . DP=19;I16=4,14,0,0,672,25672,0,0,1049,62041,0,0,352,8022,0,0;QS=3,0;MQSB=0.977696;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,18:1:0 0,15,134:5:0 +X 2381 . C <*> 0 . DP=18;I16=4,14,0,0,676,25626,0,0,1049,62041,0,0,373,8555,0,0;QS=3,0;MQSB=0.977696;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,28:1:0 0,15,133:5:0 +X 2382 . A <*> 0 . DP=19;I16=5,14,0,0,669,23995,0,0,1109,65641,0,0,369,8475,0,0;QS=3,0;MQSB=0.97357;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,28:1:0 0,15,131:5:0 +X 2383 . A <*> 0 . DP=19;I16=5,14,0,0,686,25162,0,0,1109,65641,0,0,365,8359,0,0;QS=3,0;MQSB=0.97357;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,26:1:0 0,15,140:5:0 +X 2384 . A <*> 0 . DP=19;I16=5,14,0,0,649,22943,0,0,1109,65641,0,0,360,8210,0,0;QS=3,0;MQSB=0.97357;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,13:1:0 0,15,132:5:0 +X 2385 . A <*> 0 . DP=18;I16=4,14,0,0,643,23235,0,0,1049,62041,0,0,356,8078,0,0;QS=3,0;MQSB=0.977696;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,38:1:0 0,15,134:5:0 +X 2386 . C <*> 0 . DP=18;I16=4,14,0,0,652,24008,0,0,1049,62041,0,0,351,7913,0,0;QS=3,0;MQSB=0.977696;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,25:1:0 0,15,130:5:0 +X 2387 . C <*> 0 . DP=18;I16=4,14,0,0,667,25007,0,0,1049,62041,0,0,345,7717,0,0;QS=3,0;MQSB=0.977696;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,25:1:0 0,15,128:5:0 +X 2388 . C <*> 0 . DP=18;I16=4,14,0,0,691,26659,0,0,1049,62041,0,0,339,7541,0,0;QS=3,0;MQSB=0.977696;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,39:1:0 0,15,134:5:0 +X 2389 . A <*> 0 . DP=19;I16=5,14,0,0,682,24912,0,0,1109,65641,0,0,333,7385,0,0;QS=3,0;MQSB=0.97357;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,35:1:0 0,15,140:5:0 +X 2390 . G <*> 0 . DP=18;I16=5,13,0,0,642,23418,0,0,1049,62041,0,0,328,7200,0,0;QS=3,0;MQSB=0.970092;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,27:1:0 0,15,126:5:0 +X 2391 . T <*> 0 . DP=18;I16=5,12,0,0,624,23122,0,0,989,58441,0,0,298,6412,0,0;QS=2,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,0,0:0:0 0,15,140:5:0 +X 2392 . C <*> 0 . DP=18;I16=5,12,0,0,660,25910,0,0,989,58441,0,0,291,6171,0,0;QS=2,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,0,0:0:0 0,15,131:5:0 +X 2393 . T <*> 0 . DP=18;I16=5,13,0,0,669,25099,0,0,1049,62041,0,0,309,6577,0,0;QS=3,0;MQSB=0.970092;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,38:1:0 0,15,134:5:0 +X 2394 . C <*> 0 . DP=17;I16=5,12,0,0,653,25323,0,0,989,58441,0,0,303,6379,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,29:1:0 0,15,133:5:0 +X 2395 . T <*> 0 . DP=17;I16=5,12,0,0,613,22621,0,0,989,58441,0,0,297,6201,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,19:1:0 0,15,128:5:0 +X 2396 . A <*> 0 . DP=17;I16=5,11,0,0,584,21426,0,0,929,54841,0,0,266,5418,0,0;QS=2,0;MQSB=0.960687;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,0,0:0:0 0,15,130:5:0 +X 2397 . C <*> 0 . DP=18;I16=5,13,0,0,650,24046,0,0,1049,62041,0,0,284,5856,0,0;QS=3,0;MQSB=0.970092;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,18:1:0 0,15,129:5:0 +X 2398 . A <*> 0 . DP=18;I16=5,13,0,0,617,21907,0,0,1049,62041,0,0,278,5692,0,0;QS=3,0;MQSB=0.970092;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,19:1:0 0,15,128:5:0 +X 2399 . A <*> 0 . DP=17;I16=5,11,0,0,592,22176,0,0,929,54841,0,0,248,4926,0,0;QS=2,0;MQSB=0.960687;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,0,0:0:0 0,12,115:4:0 +X 2400 . A <*> 0 . DP=16;I16=5,11,0,0,576,21010,0,0,929,54841,0,0,269,5431,0,0;QS=3,0;MQSB=0.960687;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,26:1:0 0,9,99:3:0 +X 2401 . A <*> 0 . DP=17;I16=6,11,0,0,594,21126,0,0,989,58441,0,0,265,5331,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,23:1:0 0,9,98:3:0 +X 2402 . A <*> 0 . DP=17;I16=6,11,0,0,606,21986,0,0,989,58441,0,0,262,5252,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,27:1:0 0,9,99:3:0 +X 2403 . A <*> 0 . DP=17;I16=6,11,0,0,608,22130,0,0,989,58441,0,0,259,5195,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,21:1:0 0,9,97:3:0 +X 2404 . T <*> 0 . DP=17;I16=6,11,0,0,567,19449,0,0,989,58441,0,0,256,5160,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,14:1:0 0,9,87:3:0 +X 2405 . A <*> 0 . DP=18;I16=7,11,0,0,618,21666,0,0,1049,62041,0,0,253,5147,0,0;QS=3,0;MQSB=0.951002;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,17:1:0 0,9,88:3:0 +X 2406 . C <*> 0 . DP=18;I16=7,11,0,0,676,25664,0,0,1049,62041,0,0,250,5108,0,0;QS=3,0;MQSB=0.951002;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,27:1:0 0,9,90:3:0 +X 2407 . A <*> 0 . DP=19;I16=8,11,0,0,673,24197,0,0,1109,65641,0,0,246,5046,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,3,34:1:0 0,9,89:3:0 +X 2408 . A <*> 0 . DP=18;I16=8,10,0,0,619,21951,0,0,1049,62041,0,0,243,4961,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,3,22:1:0 0,6,73:2:0 +X 2409 . A <*> 0 . DP=17;I16=8,9,0,0,615,22687,0,0,1020,61200,0,0,240,4852,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,39:1:0 0,6,74:2:0 +X 2410 . A <*> 0 . DP=17;I16=8,9,0,0,604,21938,0,0,1020,61200,0,0,237,4769,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,39:1:0 0,6,73:2:0 +X 2411 . A <*> 0 . DP=16;I16=7,9,0,0,567,20551,0,0,960,57600,0,0,235,4711,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,25:1:0 0,6,70:2:0 +X 2412 . A <*> 0 . DP=15;I16=7,8,0,0,527,18903,0,0,900,54000,0,0,234,4676,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,21:1:0 0,6,70:2:0 +X 2413 . C <*> 0 . DP=15;I16=7,8,0,0,559,21161,0,0,900,54000,0,0,233,4663,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,22:1:0 0,6,72:2:0 +X 2414 . A <*> 0 . DP=16;I16=8,8,0,0,570,20822,0,0,929,54841,0,0,232,4672,0,0;QS=3,0;MQSB=0.915545;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,25:1:0 0,6,73:2:0 +X 2415 . A <*> 0 . DP=16;I16=9,7,0,0,574,20768,0,0,929,54841,0,0,232,4652,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,30:1:0 0,6,64:2:0 +X 2416 . C <*> 0 . DP=17;I16=8,8,0,0,576,21424,0,0,960,57600,0,0,231,4649,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,42:2:0 0,6,68:2:0 +X 2417 . T <*> 0 . DP=17;I16=10,7,0,0,612,22740,0,0,958,55682,0,0,235,4627,0,0;QS=3,0;MQSB=0.79189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,57:2:0 0,9,92:3:0 +X 2418 . A <*> 0 . DP=17;I16=10,7,0,0,624,23210,0,0,958,55682,0,0,238,4626,0,0;QS=3,0;MQSB=0.79189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,62:2:0 0,9,105:3:0 +X 2419 . G <*> 0 . DP=19;I16=11,7,0,0,651,24113,0,0,1018,59282,0,0,241,4651,0,0;QS=3,0;MQSB=0.817948;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,51:2:0 0,12,126:4:0 +X 2420 . C <*> 0 . DP=19;I16=11,8,0,0,663,23999,0,0,1078,62882,0,0,246,4704,0,0;QS=3,0;MQSB=0.803979;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,44:2:0 0,12,127:4:0 +X 2421 . C <*> 0 . DP=19;I16=10,8,0,0,657,24779,0,0,1049,62041,0,0,244,4738,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,45:2:0 0,12,126:4:0 +X 2422 . A <*> 0 . DP=18;I16=11,6,0,0,647,24747,0,0,958,55682,0,0,238,4538,0,0;QS=3,0;MQSB=0.833753;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,33:1:0 0,12,137:4:0 +X 2423 . G <*> 0 . DP=18;I16=11,6,0,0,634,24250,0,0,958,55682,0,0,258,4972,0,0;QS=3,0;MQSB=0.833753;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,54:2:0 0,12,126:4:0 +X 2424 . G <*> 0 . DP=18;I16=10,6,0,0,595,22361,0,0,929,54841,0,0,240,4714,0,0;QS=3,0;MQSB=0.948436;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,36:1:0 0,12,126:4:0 +X 2425 . C <*> 0 . DP=18;I16=10,7,0,0,596,21716,0,0,989,58441,0,0,260,5074,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,45:2:0 0,12,114:4:0 +X 2426 . G <*> 0 . DP=18;I16=10,7,0,0,550,18088,0,0,989,58441,0,0,263,5171,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,33,232:11:0 0,6,59:2:0 0,12,113:4:0 +X 2427 . T <*> 0 . DP=18;I16=11,6,0,0,618,22654,0,0,958,55682,0,0,275,5403,0,0;QS=3,0;MQSB=0.833753;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,62:2:0 0,9,99:3:0 +X 2428 . G <*> 0 . DP=18;I16=11,7,0,0,649,24633,0,0,1018,59282,0,0,281,5535,0,0;QS=3,0;MQSB=0.817948;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,48:2:0 0,12,128:4:0 +X 2429 . G <*> 0 . DP=18;I16=10,7,0,0,553,19057,0,0,989,58441,0,0,269,5459,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,33,241:11:0 0,6,55:2:0 0,12,117:4:0 +X 2430 . T A,<*> 0 . DP=18;I16=10,7,1,0,552,18556,21,441,989,58441,29,841,271,5603,16,256;QS=2.94278,0.0572207,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.817948;BQB=1;MQ0F=0 PL:DP:DV 0,15,212,33,215,222:12:1 0,6,60,6,60,60:2:0 0,12,125,12,125,125:4:0 +X 2431 . G <*> 0 . DP=18;I16=11,5,0,0,580,21766,0,0,898,52082,0,0,268,5764,0,0;QS=3,0;MQSB=0.851779;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,37:1:0 0,9,98:3:0 +X 2432 . G <*> 0 . DP=17;I16=10,7,0,0,593,21479,0,0,958,55682,0,0,295,6179,0,0;QS=3,0;MQSB=0.79189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,53:2:0 0,9,97:3:0 +X 2433 . T <*> 0 . DP=17;I16=10,7,0,0,577,20425,0,0,958,55682,0,0,299,6321,0,0;QS=3,0;MQSB=0.79189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,57:2:0 0,9,94:3:0 +X 2434 . G <*> 0 . DP=17;I16=10,6,0,0,546,19340,0,0,929,54841,0,0,284,6082,0,0;QS=3,0;MQSB=0.948436;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,46:2:0 0,6,62:2:0 +X 2435 . C <*> 0 . DP=18;I16=12,5,0,0,597,21843,0,0,958,55682,0,0,304,6626,0,0;QS=3,0;MQSB=0.870325;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,58:2:0 0,6,60:2:0 +X 2436 . A <*> 0 . DP=18;I16=11,6,0,0,545,18599,0,0,989,58441,0,0,295,6379,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,64:3:0 0,6,61:2:0 +X 2437 . C <*> 0 . DP=18;I16=11,5,0,0,573,21195,0,0,929,54841,0,0,297,6541,0,0;QS=3,0;MQSB=0.960687;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,63:2:0 0,6,63:2:0 +X 2438 . A <*> 0 . DP=19;I16=12,6,0,0,583,20111,0,0,1018,59282,0,0,328,7322,0,0;QS=3,0;MQSB=0.85394;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,65:2:0 0,6,65:2:0 +X 2439 . C <*> 0 . DP=19;I16=11,7,0,0,635,22997,0,0,1049,62041,0,0,314,6974,0,0;QS=3,0;MQSB=0.951002;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,91:3:0 0,6,57:2:0 +X 2440 . C <*> 0 . DP=21;I16=13,7,0,0,701,26195,0,0,1138,66482,0,0,346,7840,0,0;QS=3,0;MQSB=0.857404;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,114:4:0 0,6,66:2:0 +X 2441 . T <*> 0 . DP=21;I16=13,8,0,0,788,29910,0,0,1198,70082,0,0,360,8068,0,0;QS=3,0;MQSB=0.845496;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,164:5:0 0,6,67:2:0 +X 2442 . G <*> 0 . DP=20;I16=12,7,0,0,695,25957,0,0,1109,65641,0,0,342,7596,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,128:4:0 0,6,66:2:0 +X 2443 . T <*> 0 . DP=20;I16=13,7,0,0,697,24685,0,0,1138,66482,0,0,373,8345,0,0;QS=3,0;MQSB=0.857404;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,130:4:0 0,6,64:2:0 +X 2444 . A <*> 0 . DP=21;I16=13,8,0,0,755,27981,0,0,1198,70082,0,0,379,8489,0,0;QS=3,0;MQSB=0.845496;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,140:4:0 0,6,64:2:0 +X 2445 . G <*> 0 . DP=21;I16=12,8,0,0,731,27427,0,0,1169,69241,0,0,359,7927,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,130:4:0 0,6,65:2:0 +X 2446 . T <*> 0 . DP=21;I16=13,8,0,0,723,25707,0,0,1198,70082,0,0,389,8633,0,0;QS=3,0;MQSB=0.845496;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,128:4:0 0,6,65:2:0 +X 2447 . C <*> 0 . DP=22;I16=14,8,0,0,770,27950,0,0,1258,73682,0,0,394,8732,0,0;QS=3,0;MQSB=0.86151;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,127:4:0 0,6,64:2:0 +X 2448 . C <*> 0 . DP=23;I16=14,7,0,0,727,26165,0,0,1167,67323,0,0,388,8674,0,0;QS=3,0;MQSB=0.735784;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,129:5:0 0,6,66:2:0 +X 2449 . C <*> 0 . DP=23;I16=13,8,0,0,727,26415,0,0,1198,70082,0,0,363,7787,0,0;QS=3,0;MQSB=0.845496;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,128:5:0 0,6,62:2:0 +X 2450 . A <*> 0 . DP=22;I16=12,8,0,0,673,24267,0,0,1138,66482,0,0,371,7959,0,0;QS=3,0;MQSB=0.826565;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,143:5:0 0,6,65:2:0 +X 2451 . G <*> 0 . DP=22;I16=14,8,0,0,821,31595,0,0,1227,70923,0,0,429,9401,0,0;QS=3,0;MQSB=0.715049;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,151:5:0 0,6,67:2:0 +X 2452 . C <*> 0 . DP=22;I16=14,8,0,0,743,26557,0,0,1227,70923,0,0,437,9613,0,0;QS=3,0;MQSB=0.715049;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,137:5:0 0,6,66:2:0 +X 2453 . T <*> 0 . DP=22;I16=14,8,0,0,775,28215,0,0,1227,70923,0,0,445,9845,0,0;QS=3,0;MQSB=0.715049;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,143:5:0 0,6,68:2:0 +X 2454 . A <*> 0 . DP=22;I16=14,8,0,0,721,24545,0,0,1227,70923,0,0,453,10097,0,0;QS=3,0;MQSB=0.715049;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,145:5:0 0,6,64:2:0 +X 2455 . C <*> 0 . DP=22;I16=14,8,0,0,776,28212,0,0,1227,70923,0,0,461,10369,0,0;QS=3,0;MQSB=0.715049;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,138:5:0 0,6,65:2:0 +X 2456 . T <*> 0 . DP=24;I16=14,9,0,0,834,30902,0,0,1318,77282,0,0,444,10036,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,168:6:0 0,6,60:2:0 +X 2457 . C <*> 0 . DP=24;I16=15,9,0,0,816,29244,0,0,1347,78123,0,0,478,10924,0,0;QS=3,0;MQSB=0.72325;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,159:6:0 0,6,65:2:0 +X 2458 . A <*> 0 . DP=24;I16=15,9,0,0,869,32555,0,0,1347,78123,0,0,487,11209,0,0;QS=3,0;MQSB=0.72325;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,166:6:0 0,6,65:2:0 +X 2459 . G T,<*> 0 . DP=24;I16=13,9,1,0,822,31186,13,169,1289,76441,29,841,453,10551,17,289;QS=2.92973,0.0702703,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.851535;BQB=1;MQ0F=0 PL:DP:DV 0,45,255,45,255,255:15:0 0,5,138,15,141,144:6:1 0,6,64,6,64,64:2:0 +X 2460 . G <*> 0 . DP=24;I16=14,9,0,0,834,31432,0,0,1318,77282,0,0,477,11065,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,160:6:0 0,6,65:2:0 +X 2461 . A G,<*> 0 . DP=24;I16=14,9,1,0,839,31487,13,169,1318,77282,29,841,489,11521,19,361;QS=2.93401,0.0659898,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.72325;BQB=1;MQ0F=0 PL:DP:DV 0,48,255,48,255,255:16:0 0,5,148,15,151,154:6:1 0,6,67,6,67,67:2:0 +X 2462 . G <*> 0 . DP=25;I16=15,10,0,0,893,33155,0,0,1407,81723,0,0,514,12090,0,0;QS=3,0;MQSB=0.707404;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,165:6:0 0,6,66:2:0 +X 2463 . G T,<*> 0 . DP=25;I16=12,10,1,0,777,28525,14,196,1289,76441,29,841,452,10720,25,625;QS=2.975,0.025,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.825053;BQB=1;MQ0F=0 PL:DP:DV 0,36,255,48,255,255:17:1 0,12,133,12,133,133:4:0 0,6,68,6,68,68:2:0 +X 2464 . C <*> 0 . DP=25;I16=15,10,0,0,904,34194,0,0,1407,81723,0,0,526,12458,0,0;QS=3,0;MQSB=0.707404;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,149:6:0 0,6,67:2:0 +X 2465 . T <*> 0 . DP=25;I16=14,10,0,0,857,32235,0,0,1347,78123,0,0,506,11994,0,0;QS=3,0;MQSB=0.679965;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,163:6:0 0,6,69:2:0 +X 2466 . G <*> 0 . DP=24;I16=14,9,0,0,852,32336,0,0,1318,77282,0,0,509,12025,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,157:6:0 0,6,63:2:0 +X 2467 . A <*> 0 . DP=24;I16=14,9,0,0,829,30725,0,0,1318,77282,0,0,513,12121,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,168:6:0 0,6,67:2:0 +X 2468 . G <*> 0 . DP=24;I16=15,9,0,0,890,34034,0,0,1347,78123,0,0,541,12807,0,0;QS=3,0;MQSB=0.72325;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,169:6:0 0,6,64:2:0 +X 2469 . G <*> 0 . DP=24;I16=15,9,0,0,865,32303,0,0,1347,78123,0,0,544,12882,0,0;QS=3,0;MQSB=0.72325;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,174:6:0 0,6,58:2:0 +X 2470 . G <*> 0 . DP=24;I16=14,9,0,0,829,30785,0,0,1318,77282,0,0,521,12295,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,178:6:0 0,6,58:2:0 +X 2471 . G <*> 0 . DP=24;I16=14,9,0,0,833,31429,0,0,1318,77282,0,0,523,12345,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,170:5:0 0,6,64:2:0 +X 2472 . G <*> 0 . DP=24;I16=13,9,0,0,774,28428,0,0,1289,76441,0,0,499,11733,0,0;QS=3,0;MQSB=0.955854;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,154:5:0 0,6,56:2:0 +X 2473 . A <*> 0 . DP=24;I16=13,9,0,0,775,28137,0,0,1258,73682,0,0,508,12078,0,0;QS=3,0;MQSB=0.834768;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,160:5:0 0,6,63:2:0 +X 2474 . A <*> 0 . DP=25;I16=15,9,0,0,851,31665,0,0,1378,80882,0,0,524,12322,0,0;QS=3,0;MQSB=0.865888;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,160:5:0 0,9,80:3:0 +X 2475 . G <*> 0 . DP=25;I16=15,9,0,0,913,35239,0,0,1378,80882,0,0,525,12323,0,0;QS=3,0;MQSB=0.865888;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,167:5:0 0,9,84:3:0 +X 2476 . G <*> 0 . DP=25;I16=13,9,0,0,776,28584,0,0,1289,76441,0,0,488,11544,0,0;QS=3,0;MQSB=0.955854;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,138:5:0 0,9,82:3:0 +X 2477 . A <*> 0 . DP=25;I16=14,9,0,0,867,34329,0,0,1318,77282,0,0,515,12223,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,178:5:0 0,9,91:3:0 +X 2478 . C <*> 0 . DP=25;I16=14,9,0,0,897,36911,0,0,1318,77282,0,0,517,12289,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,175:5:0 0,9,87:3:0 +X 2479 . T <*> 0 . DP=25;I16=15,9,0,0,921,37957,0,0,1378,80882,0,0,529,12467,0,0;QS=3,0;MQSB=0.865888;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,176:5:0 0,9,97:3:0 +X 2480 . G <*> 0 . DP=25;I16=14,9,0,0,877,35485,0,0,1349,80041,0,0,504,11864,0,0;QS=3,0;MQSB=0.960618;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,176:5:0 0,9,88:3:0 +X 2481 . C <*> 0 . DP=25;I16=13,9,0,0,848,34542,0,0,1289,76441,0,0,496,11838,0,0;QS=3,0;MQSB=0.955854;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,183:5:0 0,9,88:3:0 +X 2482 . T <*> 0 . DP=25;I16=15,9,0,0,905,37331,0,0,1378,80882,0,0,526,12430,0,0;QS=3,0;MQSB=0.865888;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,178:5:0 0,9,96:3:0 +X 2483 . T <*> 0 . DP=25;I16=14,9,0,0,879,36187,0,0,1318,77282,0,0,517,12311,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,180:5:0 0,9,89:3:0 +X 2484 . G <*> 0 . DP=25;I16=14,9,0,0,884,35142,0,0,1349,80041,0,0,494,11604,0,0;QS=3,0;MQSB=0.960618;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,174:5:0 0,9,84:3:0 +X 2485 . A T,<*> 0 . DP=25;I16=14,9,1,0,891,36757,17,289,1349,80041,29,841,490,11502,25,625;QS=2.96926,0.0307414,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.865888;BQB=1;MQ0F=0 PL:DP:DV 0,31,255,45,255,255:16:1 0,15,193,15,193,193:5:0 0,9,93,9,93,93:3:0 +X 2486 . G <*> 0 . DP=25;I16=15,9,0,0,898,36230,0,0,1378,80882,0,0,511,12041,0,0;QS=3,0;MQSB=0.865888;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,153:5:0 0,9,90:3:0 +X 2487 . C <*> 0 . DP=25;I16=14,9,0,0,793,30695,0,0,1349,80041,0,0,482,11346,0,0;QS=3,0;MQSB=0.960618;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,175:5:0 0,9,91:3:0 +X 2488 . C <*> 0 . DP=25;I16=13,9,0,0,841,34597,0,0,1289,76441,0,0,457,10841,0,0;QS=3,0;MQSB=0.955854;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,174:5:0 0,9,93:3:0 +X 2489 . C <*> 0 . DP=23;I16=11,9,0,0,801,34227,0,0,1169,69241,0,0,454,10788,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,187:5:0 0,9,93:3:0 +X 2490 . A <*> 0 . DP=23;I16=11,10,0,0,818,34642,0,0,1229,72841,0,0,451,10695,0,0;QS=3,0;MQSB=0.939898;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,175:5:0 0,12,128:4:0 +X 2491 . G <*> 0 . DP=23;I16=12,10,0,0,845,35143,0,0,1258,73682,0,0,471,11097,0,0;QS=3,0;MQSB=0.804615;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,178:5:0 0,12,121:4:0 +X 2492 . G A,<*> 0 . DP=23;I16=11,10,1,0,845,36207,16,256,1229,72841,29,841,446,10494,21,441;QS=2.96708,0.0329218,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.804615;BQB=1;MQ0F=0 PL:DP:DV 0,22,255,36,255,255:13:1 0,15,187,15,187,187:5:0 0,12,124,12,124,124:4:0 +X 2493 . A G,<*> 0 . DP=23;I16=11,10,1,0,855,37007,13,169,1229,72841,29,841,442,10340,20,400;QS=2.97269,0.0273109,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.804615;BQB=1;MQ0F=0 PL:DP:DV 0,25,255,36,255,255:13:1 0,15,191,15,191,191:5:0 0,12,127,12,127,127:4:0 +X 2494 . G <*> 0 . DP=23;I16=11,10,0,0,802,32720,0,0,1229,72841,0,0,437,10153,0,0;QS=3,0;MQSB=0.939898;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,179:5:0 0,12,118:4:0 +X 2495 . T <*> 0 . DP=23;I16=10,10,0,0,737,29861,0,0,1138,66482,0,0,413,9513,0,0;QS=3,0;MQSB=0.751477;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,172:5:0 0,12,113:4:0 +X 2496 . T <*> 0 . DP=23;I16=12,10,0,0,815,32793,0,0,1258,73682,0,0,442,10026,0,0;QS=3,0;MQSB=0.804615;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,183:5:0 0,12,123:4:0 +X 2497 . T <*> 0 . DP=22;I16=12,9,0,0,807,33723,0,0,1198,70082,0,0,436,9814,0,0;QS=3,0;MQSB=0.815018;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,177:5:0 0,12,131:4:0 +X 2498 . G <*> 0 . DP=22;I16=12,9,0,0,808,33264,0,0,1198,70082,0,0,430,9622,0,0;QS=3,0;MQSB=0.815018;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,173:5:0 0,12,127:4:0 +X 2499 . A <*> 0 . DP=22;I16=12,9,0,0,847,36803,0,0,1198,70082,0,0,424,9450,0,0;QS=3,0;MQSB=0.815018;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,185:5:0 0,12,133:4:0 +X 2500 . G <*> 0 . DP=22;I16=11,9,0,0,772,32546,0,0,1169,69241,0,0,404,9078,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,168:5:0 0,12,129:4:0 +X 2501 . G <*> 0 . DP=22;I16=11,8,0,0,768,33120,0,0,1109,65641,0,0,373,8293,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,146:4:0 0,12,118:4:0 +X 2502 . C <*> 0 . DP=22;I16=12,8,0,0,798,33902,0,0,1138,66482,0,0,378,8270,0,0;QS=3,0;MQSB=0.826565;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,155:4:0 0,12,125:4:0 +X 2503 . T <*> 0 . DP=22;I16=12,9,0,0,851,36841,0,0,1198,70082,0,0,396,8746,0,0;QS=3,0;MQSB=0.815018;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,180:5:0 0,12,139:4:0 +X 2504 . G <*> 0 . DP=22;I16=12,9,0,0,787,31955,0,0,1198,70082,0,0,389,8615,0,0;QS=3,0;MQSB=0.815018;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,171:5:0 0,12,129:4:0 +X 2505 . C <*> 0 . DP=21;I16=11,9,0,0,792,33440,0,0,1138,66482,0,0,383,8501,0,0;QS=3,0;MQSB=0.791547;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,169:5:0 0,12,132:4:0 +X 2506 . T <*> 0 . DP=22;I16=11,10,0,0,798,32868,0,0,1198,70082,0,0,376,8354,0,0;QS=3,0;MQSB=0.780412;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,175:5:0 0,15,169:5:0 +X 2507 . G <*> 0 . DP=21;I16=9,10,0,0,716,30074,0,0,1109,65641,0,0,365,8189,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,15,163:5:0 0,15,153:5:0 +X 2508 . T <*> 0 . DP=21;I16=9,10,0,0,724,30396,0,0,1109,65641,0,0,361,8089,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,15,158:5:0 0,15,162:5:0 +X 2509 . G T,<*> 0 . DP=21;I16=8,10,1,0,710,30408,35,1225,1049,62041,60,3600,330,7282,25,625;QS=2.80663,0.19337,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.920044;BQB=1;MQ0F=0 PL:DP:DV 0,27,253,27,253,253:9:0 20,0,122,32,125,150:5:1 0,15,163,15,163,163:5:0 +X 2510 . A <*> 0 . DP=21;I16=10,10,0,0,778,33128,0,0,1138,66482,0,0,352,7754,0,0;QS=3,0;MQSB=0.751477;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,174:5:0 0,15,161:5:0 +X 2511 . G <*> 0 . DP=21;I16=10,10,0,0,771,32165,0,0,1138,66482,0,0,344,7558,0,0;QS=3,0;MQSB=0.751477;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,161:5:0 0,15,159:5:0 +X 2512 . C <*> 0 . DP=21;I16=10,10,0,0,790,33406,0,0,1138,66482,0,0,336,7386,0,0;QS=3,0;MQSB=0.751477;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,175:5:0 0,15,160:5:0 +X 2513 . T <*> 0 . DP=21;I16=10,10,0,0,755,31503,0,0,1138,66482,0,0,327,7189,0,0;QS=3,0;MQSB=0.751477;MQ0F=0 PL:DP:DV 0,30,246:10:0 0,15,180:5:0 0,15,156:5:0 +X 2514 . G <*> 0 . DP=20;I16=9,10,0,0,702,28002,0,0,1109,65641,0,0,319,7017,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,15,171:5:0 0,15,155:5:0 +X 2515 . T <*> 0 . DP=19;I16=8,10,0,0,642,25888,0,0,1049,62041,0,0,312,6868,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,24,182:8:0 0,15,172:5:0 0,15,141:5:0 +X 2516 . G <*> 0 . DP=19;I16=8,10,0,0,685,28155,0,0,1049,62041,0,0,303,6641,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,24,211:8:0 0,15,175:5:0 0,15,147:5:0 +X 2517 . A <*> 0 . DP=18;I16=8,9,0,0,660,27600,0,0,989,58441,0,0,295,6435,0,0;QS=3,0;MQSB=0.91051;MQ0F=0 PL:DP:DV 0,24,215:8:0 0,12,139:4:0 0,15,161:5:0 +X 2518 . T <*> 0 . DP=17;I16=6,9,0,0,611,26911,0,0,900,54000,0,0,273,6023,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,188:7:0 0,12,144:4:0 0,12,146:4:0 +X 2519 . C <*> 0 . DP=16;I16=7,8,0,0,531,20111,0,0,900,54000,0,0,282,6078,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,175:7:0 0,12,141:4:0 0,12,125:4:0 +X 2520 . G <*> 0 . DP=15;I16=6,8,0,0,501,19731,0,0,840,50400,0,0,277,5923,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,187:7:0 0,12,129:4:0 0,9,101:3:0 +X 2521 . C <*> 0 . DP=15;I16=6,8,0,0,583,25777,0,0,840,50400,0,0,272,5782,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,214:7:0 0,12,149:4:0 0,9,111:3:0 +X 2522 . A <*> 0 . DP=16;I16=6,8,0,0,516,20930,0,0,840,50400,0,0,266,5606,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,173:7:0 0,12,139:4:0 0,9,114:3:0 +X 2523 . T <*> 0 . DP=16;I16=6,9,0,0,588,25538,0,0,900,54000,0,0,270,5546,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,207:7:0 0,15,157:5:0 0,9,117:3:0 +X 2524 . C <*> 0 . DP=16;I16=5,9,0,0,548,23502,0,0,840,50400,0,0,256,5342,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,182:6:0 0,15,156:5:0 0,9,112:3:0 +X 2525 . A C,<*> 0 . DP=17;I16=6,9,0,1,550,23138,28,784,900,54000,60,3600,248,5174,12,144;QS=2.86,0.14,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,24,168,24,168,168:8:0 13,0,138,25,141,159:5:1 0,9,117,9,117,117:3:0 +X 2526 . C <*> 0 . DP=18;I16=6,11,0,0,677,28649,0,0,1020,61200,0,0,256,5232,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,229:9:0 0,15,183:5:0 0,9,113:3:0 +X 2527 . T <*> 0 . DP=18;I16=6,11,0,0,674,29286,0,0,1020,61200,0,0,252,5118,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,217:9:0 0,15,183:5:0 0,9,119:3:0 +X 2528 . G <*> 0 . DP=18;I16=6,11,0,0,701,30729,0,0,1020,61200,0,0,248,5028,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,234:9:0 0,15,184:5:0 0,9,119:3:0 +X 2529 . C <*> 0 . DP=18;I16=6,11,0,0,676,28974,0,0,1020,61200,0,0,244,4962,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,15,175:5:0 0,9,117:3:0 +X 2530 . A <*> 0 . DP=18;I16=6,10,0,0,624,26620,0,0,960,57600,0,0,223,4631,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,209:9:0 0,12,153:4:0 0,9,116:3:0 +X 2531 . T <*> 0 . DP=17;I16=6,10,0,0,641,27911,0,0,960,57600,0,0,236,4852,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,210:8:0 0,15,175:5:0 0,9,122:3:0 +X 2532 . T <*> 0 . DP=17;I16=6,10,0,0,634,27460,0,0,960,57600,0,0,230,4708,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,212:8:0 0,15,173:5:0 0,9,117:3:0 +X 2533 . C <*> 0 . DP=18;I16=6,11,0,0,614,24196,0,0,1020,61200,0,0,224,4588,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,212:9:0 0,15,159:5:0 0,9,104:3:0 +X 2534 . C <*> 0 . DP=16;I16=5,10,0,0,595,25141,0,0,900,54000,0,0,221,4491,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,202:8:0 0,12,144:4:0 0,9,110:3:0 +X 2535 . A <*> 0 . DP=16;I16=5,10,0,0,617,27711,0,0,900,54000,0,0,218,4416,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,204:8:0 0,12,136:4:0 0,9,123:3:0 +X 2536 . G <*> 0 . DP=15;I16=4,10,0,0,543,23023,0,0,840,50400,0,0,216,4362,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,195:8:0 0,9,102:3:0 0,9,117:3:0 +X 2537 . C <*> 0 . DP=15;I16=4,10,0,0,555,24075,0,0,840,50400,0,0,213,4279,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,195:8:0 0,9,113:3:0 0,9,115:3:0 +X 2538 . C <*> 0 . DP=15;I16=5,9,0,0,510,21070,0,0,840,50400,0,0,211,4217,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,157:7:0 0,9,129:3:0 0,12,126:4:0 +X 2539 . C <*> 0 . DP=15;I16=5,9,0,0,464,16896,0,0,840,50400,0,0,209,4125,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,146:7:0 0,9,122:3:0 0,12,111:4:0 +X 2540 . G <*> 0 . DP=16;I16=6,9,0,0,548,21860,0,0,900,54000,0,0,207,4053,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,189:7:0 0,12,139:4:0 0,12,110:4:0 +X 2541 . G <*> 0 . DP=15;I16=5,9,0,0,535,22527,0,0,840,50400,0,0,207,4001,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,170:7:0 0,9,117:3:0 0,12,140:4:0 +X 2542 . T <*> 0 . DP=15;I16=4,9,0,0,527,23207,0,0,780,46800,0,0,203,3953,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,183:7:0 0,9,125:3:0 0,9,109:3:0 +X 2543 . G <*> 0 . DP=15;I16=5,9,0,0,540,23004,0,0,840,50400,0,0,207,3957,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,196:7:0 0,9,117:3:0 0,12,117:4:0 +X 2544 . A <*> 0 . DP=16;I16=6,9,0,0,569,24139,0,0,900,54000,0,0,207,3965,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,202:8:0 0,9,119:3:0 0,12,132:4:0 +X 2545 . C <*> 0 . DP=16;I16=6,9,0,0,583,24657,0,0,900,54000,0,0,208,3994,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,217:8:0 0,9,118:3:0 0,12,130:4:0 +X 2546 . A <*> 0 . DP=16;I16=6,9,0,0,608,27290,0,0,900,54000,0,0,209,4045,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,206:8:0 0,9,133:3:0 0,12,144:4:0 +X 2547 . G <*> 0 . DP=16;I16=6,9,0,0,597,26215,0,0,900,54000,0,0,211,4117,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,191:7:0 0,9,131:3:0 0,15,150:5:0 +X 2548 . A <*> 0 . DP=16;I16=6,9,0,0,632,28806,0,0,900,54000,0,0,214,4210,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,196:7:0 0,9,131:3:0 0,15,171:5:0 +X 2549 . G <*> 0 . DP=16;I16=6,9,0,0,594,25254,0,0,900,54000,0,0,217,4325,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,180:7:0 0,9,132:3:0 0,15,160:5:0 +X 2550 . T <*> 0 . DP=16;I16=6,9,0,0,572,24134,0,0,900,54000,0,0,219,4413,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,182:7:0 0,9,122:3:0 0,15,148:5:0 +X 2551 . G <*> 0 . DP=16;I16=6,9,0,0,578,24606,0,0,900,54000,0,0,220,4474,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,181:7:0 0,9,131:3:0 0,15,151:5:0 +X 2552 . A <*> 0 . DP=15;I16=6,8,0,0,585,26419,0,0,840,50400,0,0,221,4505,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,178:6:0 0,9,129:3:0 0,15,168:5:0 +X 2553 . G <*> 0 . DP=15;I16=6,8,0,0,528,21944,0,0,840,50400,0,0,222,4554,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,170:6:0 0,9,117:3:0 0,15,142:5:0 +X 2554 . T <*> 0 . DP=15;I16=6,8,0,0,543,23015,0,0,840,50400,0,0,223,4621,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,156:6:0 0,9,129:3:0 0,15,160:5:0 +X 2555 . C <*> 0 . DP=15;I16=6,8,0,0,566,24416,0,0,840,50400,0,0,224,4706,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,173:6:0 0,9,131:3:0 0,15,159:5:0 +X 2556 . A <*> 0 . DP=14;I16=6,7,0,0,487,20095,0,0,780,46800,0,0,226,4808,0,0;QS=3,0;MQSB=0.961166;MQ0F=0 PL:DP:DV 0,15,141:5:0 0,9,125:3:0 0,15,146:5:0 +X 2557 . C <*> 0 . DP=13;I16=5,8,0,0,471,17481,0,0,780,46800,0,0,249,5325,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,161:5:0 0,9,96:3:0 0,15,151:5:0 +X 2558 . T <*> 0 . DP=14;I16=5,9,0,0,535,20597,0,0,840,50400,0,0,251,5417,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,173:6:0 0,9,99:3:0 0,15,174:5:0 +X 2559 . G <*> 0 . DP=14;I16=5,9,0,0,509,18693,0,0,840,50400,0,0,253,5475,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,172:6:0 0,9,98:3:0 0,15,156:5:0 +X 2560 . T <*> 0 . DP=14;I16=5,9,0,0,489,17587,0,0,840,50400,0,0,255,5549,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,160:6:0 0,9,106:3:0 0,15,144:5:0 +X 2561 . C <*> 0 . DP=14;I16=5,9,0,0,489,17477,0,0,840,50400,0,0,257,5639,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,164:6:0 0,9,96:3:0 0,15,153:5:0 +X 2562 . T <*> 0 . DP=13;I16=5,8,0,0,460,17016,0,0,780,46800,0,0,260,5744,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,139:5:0 0,9,99:3:0 0,15,167:5:0 +X 2563 . C <*> 0 . DP=14;I16=5,8,0,0,433,15133,0,0,780,46800,0,0,263,5863,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,149:5:0 0,9,83:3:0 0,15,142:5:0 +X 2564 . A G,<*> 0 . DP=15;I16=1,4,4,5,174,6124,316,11352,300,18000,540,32400,61,1311,184,4034;QS=0.988263,2.01174,0;VDB=0.690812;SGB=-3.20711;RPB=0.197899;MQB=1;MQSB=1;BQB=0.965069;MQ0F=0 PL:DP:DV 88,0,78,98,87,171:6:3 57,0,56,63,62,117:4:2 124,12,0,124,12,124:4:4 +X 2565 . A <*> 0 . DP=15;I16=6,9,0,0,562,21216,0,0,900,54000,0,0,274,6076,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,178:6:0 0,12,134:4:0 0,15,166:5:0 +X 2566 . A <*> 0 . DP=15;I16=6,9,0,0,545,20019,0,0,900,54000,0,0,276,6098,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,181:6:0 0,12,120:4:0 0,15,162:5:0 +X 2567 . A <*> 0 . DP=16;I16=7,9,0,0,580,21342,0,0,960,57600,0,0,278,6136,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,177:6:0 0,15,151:5:0 0,15,166:5:0 +X 2568 . A <*> 0 . DP=16;I16=7,8,0,0,555,20795,0,0,900,54000,0,0,256,5566,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,180:6:0 0,12,132:4:0 0,15,167:5:0 +X 2569 . A <*> 0 . DP=17;I16=7,10,0,0,661,25943,0,0,1020,61200,0,0,284,6264,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,213:7:0 0,15,163:5:0 0,15,172:5:0 +X 2570 . G <*> 0 . DP=18;I16=8,10,0,0,664,24968,0,0,1080,64800,0,0,287,6305,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,213:7:0 0,15,152:5:0 0,18,176:6:0 +X 2571 . A <*> 0 . DP=18;I16=8,10,0,0,618,21870,0,0,1080,64800,0,0,291,6365,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,195:7:0 0,15,155:5:0 0,18,155:6:0 +X 2572 . A <*> 0 . DP=18;I16=8,10,0,0,631,22829,0,0,1080,64800,0,0,295,6445,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,194:7:0 0,15,150:5:0 0,18,173:6:0 +X 2573 . A <*> 0 . DP=18;I16=8,10,0,0,690,26830,0,0,1080,64800,0,0,298,6494,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,210:7:0 0,15,170:5:0 0,18,183:6:0 +X 2574 . G <*> 0 . DP=18;I16=8,10,0,0,664,24884,0,0,1080,64800,0,0,301,6561,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,211:7:0 0,15,152:5:0 0,18,176:6:0 +X 2575 . G <*> 0 . DP=18;I16=8,10,0,0,642,23904,0,0,1080,64800,0,0,305,6645,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,242:8:0 0,15,145:5:0 0,15,140:5:0 +X 2576 . A <*> 0 . DP=18;I16=7,10,0,0,595,21311,0,0,1020,61200,0,0,285,6121,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,210:8:0 0,15,153:5:0 0,12,131:4:0 +X 2577 . A <*> 0 . DP=19;I16=8,10,0,0,682,26398,0,0,1080,64800,0,0,290,6240,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,244:8:0 0,15,161:5:0 0,15,155:5:0 +X 2578 . G <*> 0 . DP=18;I16=9,9,0,0,643,24115,0,0,1080,64800,0,0,322,7002,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,249:8:0 0,12,114:4:0 0,18,161:6:0 +X 2579 . A <*> 0 . DP=18;I16=9,8,0,0,634,23870,0,0,1020,61200,0,0,304,6532,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,229:8:0 0,9,110:3:0 0,18,176:6:0 +X 2580 . A <*> 0 . DP=18;I16=9,9,0,0,629,22593,0,0,1080,64800,0,0,336,7330,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,223:8:0 0,12,117:4:0 0,18,169:6:0 +X 2581 . A <*> 0 . DP=19;I16=10,9,0,0,691,25669,0,0,1140,68400,0,0,343,7521,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,12,133:4:0 0,18,166:6:0 +X 2582 . T <*> 0 . DP=19;I16=10,9,0,0,674,24218,0,0,1140,68400,0,0,350,7682,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,235:9:0 0,12,138:4:0 0,18,168:6:0 +X 2583 . A <*> 0 . DP=19;I16=10,9,0,0,693,25465,0,0,1140,68400,0,0,357,7865,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,247:9:0 0,12,126:4:0 0,18,178:6:0 +X 2584 . A <*> 0 . DP=19;I16=10,9,0,0,702,26340,0,0,1140,68400,0,0,363,8019,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,243:9:0 0,12,134:4:0 0,18,187:6:0 +X 2585 . A <*> 0 . DP=19;I16=9,9,0,0,690,26700,0,0,1080,64800,0,0,350,7818,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,250:9:0 0,9,114:3:0 0,18,190:6:0 +X 2586 . G <*> 0 . DP=19;I16=10,9,0,0,714,27314,0,0,1140,68400,0,0,373,8283,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,12,127:4:0 0,18,176:6:0 +X 2587 . A <*> 0 . DP=20;I16=9,9,0,0,665,24781,0,0,1049,62041,0,0,343,7717,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,137:4:0 0,12,136:4:0 +X 2588 . A <*> 0 . DP=21;I16=12,9,0,0,737,26531,0,0,1229,72841,0,0,384,8620,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,138:4:0 0,18,162:6:0 +X 2589 . A <*> 0 . DP=22;I16=13,9,0,0,780,28412,0,0,1289,76441,0,0,390,8770,0,0;QS=3,0;MQSB=0.955854;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,142:4:0 0,18,170:6:0 +X 2590 . A <*> 0 . DP=22;I16=13,9,0,0,774,28352,0,0,1289,76441,0,0,396,8894,0,0;QS=3,0;MQSB=0.955854;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,135:4:0 0,18,160:6:0 +X 2591 . C <*> 0 . DP=21;I16=13,8,0,0,765,28617,0,0,1229,72841,0,0,403,9041,0,0;QS=3,0;MQSB=0.95891;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,136:4:0 0,15,136:5:0 +X 2592 . A <*> 0 . DP=21;I16=13,8,0,0,763,28325,0,0,1229,72841,0,0,410,9210,0,0;QS=3,0;MQSB=0.95891;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,140:4:0 0,15,139:5:0 +X 2593 . A <*> 0 . DP=21;I16=13,8,0,0,754,27888,0,0,1229,72841,0,0,416,9350,0,0;QS=3,0;MQSB=0.95891;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,141:4:0 0,15,147:5:0 +X 2594 . A <*> 0 . DP=21;I16=13,8,0,0,775,29179,0,0,1229,72841,0,0,422,9510,0,0;QS=3,0;MQSB=0.95891;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,130:4:0 0,15,153:5:0 +X 2595 . T <*> 0 . DP=22;I16=14,8,0,0,766,27472,0,0,1289,76441,0,0,427,9639,0,0;QS=3,0;MQSB=0.963419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,119:4:0 0,15,143:5:0 +X 2596 . A <*> 0 . DP=22;I16=13,8,0,0,751,27409,0,0,1229,72841,0,0,407,9111,0,0;QS=3,0;MQSB=0.95891;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,123:4:0 0,12,129:4:0 +X 2597 . A <*> 0 . DP=22;I16=14,8,0,0,811,30147,0,0,1289,76441,0,0,437,9851,0,0;QS=3,0;MQSB=0.963419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,145:4:0 0,15,145:5:0 +X 2598 . A <*> 0 . DP=22;I16=14,8,0,0,817,30915,0,0,1289,76441,0,0,442,9984,0,0;QS=3,0;MQSB=0.963419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,136:4:0 0,15,159:5:0 +X 2599 . A <*> 0 . DP=22;I16=14,8,0,0,800,29912,0,0,1289,76441,0,0,447,10135,0,0;QS=3,0;MQSB=0.963419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,126:4:0 0,15,150:5:0 +X 2600 . A <*> 0 . DP=22;I16=14,8,0,0,784,29138,0,0,1289,76441,0,0,451,10255,0,0;QS=3,0;MQSB=0.963419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,113:4:0 0,15,150:5:0 +X 2601 . T <*> 0 . DP=22;I16=14,8,0,0,770,27820,0,0,1289,76441,0,0,454,10344,0,0;QS=3,0;MQSB=0.963419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,118:4:0 0,15,142:5:0 +X 2602 . A <*> 0 . DP=23;I16=15,8,0,0,825,29971,0,0,1349,80041,0,0,457,10451,0,0;QS=3,0;MQSB=0.967216;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,143:4:0 0,18,154:6:0 +X 2603 . A <*> 0 . DP=23;I16=15,8,0,0,862,32840,0,0,1349,80041,0,0,460,10526,0,0;QS=3,0;MQSB=0.967216;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,138:4:0 0,18,172:6:0 +X 2604 . T <*> 0 . DP=23;I16=15,8,0,0,822,29902,0,0,1349,80041,0,0,463,10619,0,0;QS=3,0;MQSB=0.967216;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,129:4:0 0,18,154:6:0 +X 2605 . A <*> 0 . DP=23;I16=14,8,0,0,845,32617,0,0,1289,76441,0,0,441,10105,0,0;QS=3,0;MQSB=0.963419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,143:4:0 0,15,157:5:0 +X 2606 . G <*> 0 . DP=23;I16=14,8,0,0,812,30796,0,0,1289,76441,0,0,444,10234,0,0;QS=3,0;MQSB=0.963419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,129:4:0 0,15,142:5:0 +X 2607 . T <*> 0 . DP=22;I16=15,7,0,0,782,28440,0,0,1289,76441,0,0,472,10954,0,0;QS=3,0;MQSB=0.970024;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,119:4:0 0,15,132:5:0 +X 2608 . G <*> 0 . DP=22;I16=15,7,0,0,851,33169,0,0,1289,76441,0,0,474,11014,0,0;QS=3,0;MQSB=0.970024;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,132:4:0 0,15,127:5:0 +X 2609 . C <*> 0 . DP=22;I16=15,7,0,0,796,29454,0,0,1289,76441,0,0,475,11041,0,0;QS=3,0;MQSB=0.970024;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,137:4:0 0,15,124:5:0 +X 2610 . A <*> 0 . DP=22;I16=15,7,0,0,830,31684,0,0,1289,76441,0,0,476,11086,0,0;QS=3,0;MQSB=0.970024;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,146:4:0 0,15,121:5:0 +X 2611 . G <*> 0 . DP=22;I16=15,7,0,0,824,32048,0,0,1289,76441,0,0,477,11149,0,0;QS=3,0;MQSB=0.970024;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,129:4:0 0,15,122:5:0 +X 2612 . A <*> 0 . DP=22;I16=14,7,0,0,771,29035,0,0,1229,72841,0,0,453,10605,0,0;QS=3,0;MQSB=0.966484;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,130:4:0 0,12,117:4:0 +X 2613 . C <*> 0 . DP=22;I16=15,7,0,0,832,31926,0,0,1289,76441,0,0,478,11278,0,0;QS=3,0;MQSB=0.970024;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,138:4:0 0,15,120:5:0 +X 2614 . A <*> 0 . DP=21;I16=15,6,0,0,791,30065,0,0,1229,72841,0,0,477,11241,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,110:3:0 0,15,140:5:0 +X 2615 . A <*> 0 . DP=21;I16=15,6,0,0,777,29101,0,0,1229,72841,0,0,475,11167,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,99:3:0 0,15,142:5:0 +X 2616 . A <*> 0 . DP=21;I16=15,6,0,0,734,26922,0,0,1229,72841,0,0,472,11056,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,90:3:0 0,15,144:5:0 +X 2617 . A <*> 0 . DP=21;I16=15,6,0,0,810,31654,0,0,1229,72841,0,0,469,10959,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,95:3:0 0,15,140:5:0 +X 2618 . G <*> 0 . DP=23;I16=16,6,0,0,863,34219,0,0,1289,76441,0,0,441,10251,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,74:2:0 0,15,132:5:0 +X 2619 . G <*> 0 . DP=23;I16=16,6,0,0,807,30109,0,0,1289,76441,0,0,439,10135,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,66:2:0 0,15,127:5:0 +X 2620 . C <*> 0 . DP=23;I16=16,7,0,0,780,28242,0,0,1349,80041,0,0,462,10664,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,87:3:0 0,15,115:5:0 +X 2621 . C <*> 0 . DP=23;I16=16,7,0,0,860,32944,0,0,1349,80041,0,0,459,10537,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,112:3:0 0,15,124:5:0 +X 2622 . T <*> 0 . DP=24;I16=17,7,0,0,908,35474,0,0,1409,83641,0,0,456,10428,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,115:3:0 0,15,134:5:0 +X 2623 . T <*> 0 . DP=24;I16=17,7,0,0,850,30978,0,0,1409,83641,0,0,453,10289,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,114:3:0 0,15,129:5:0 +X 2624 . G <*> 0 . DP=24;I16=17,7,0,0,882,33332,0,0,1409,83641,0,0,450,10172,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,101:3:0 0,15,133:5:0 +X 2625 . A <*> 0 . DP=23;I16=17,6,0,0,855,32593,0,0,1349,80041,0,0,448,10076,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,114:3:0 0,15,135:5:0 +X 2626 . C <*> 0 . DP=23;I16=17,6,0,0,847,31625,0,0,1349,80041,0,0,446,10000,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,100:3:0 0,15,122:5:0 +X 2627 . C <*> 0 . DP=23;I16=17,6,0,0,863,32865,0,0,1349,80041,0,0,444,9944,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,104:3:0 0,15,129:5:0 +X 2628 . C <*> 0 . DP=24;I16=17,6,0,0,793,28559,0,0,1349,80041,0,0,431,9757,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,95:3:0 0,15,127:5:0 +X 2629 . A <*> 0 . DP=24;I16=18,6,0,0,893,33537,0,0,1409,83641,0,0,439,9789,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,101:3:0 0,18,148:6:0 +X 2630 . T <*> 0 . DP=24;I16=17,6,0,0,836,31094,0,0,1380,82800,0,0,412,9116,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,112:3:0 0,18,140:6:0 +X 2631 . C <*> 0 . DP=24;I16=18,6,0,0,900,34378,0,0,1409,83641,0,0,435,9713,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,104:3:0 0,18,142:6:0 +X 2632 . T <*> 0 . DP=24;I16=18,6,0,0,937,37097,0,0,1409,83641,0,0,433,9705,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,113:3:0 0,18,164:6:0 +X 2633 . A <*> 0 . DP=23;I16=18,5,0,0,801,28913,0,0,1349,80041,0,0,431,9667,0,0;QS=3,0;MQSB=0.982789;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,95:3:0 0,18,148:6:0 +X 2634 . G <*> 0 . DP=23;I16=19,3,0,0,861,34125,0,0,1289,76441,0,0,405,9023,0,0;QS=3,0;MQSB=0.989755;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,74:2:0 0,18,149:6:0 +X 2635 . C <*> 0 . DP=23;I16=19,4,0,0,848,32154,0,0,1349,80041,0,0,429,9599,0,0;QS=3,0;MQSB=0.986928;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,107:3:0 0,18,148:6:0 +X 2636 . T <*> 0 . DP=24;I16=19,4,0,0,871,33973,0,0,1349,80041,0,0,428,9572,0,0;QS=3,0;MQSB=0.986928;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,98:3:0 0,18,160:6:0 +X 2637 . T <*> 0 . DP=24;I16=19,5,0,0,871,32073,0,0,1409,83641,0,0,428,9568,0,0;QS=3,0;MQSB=0.984335;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,111:3:0 0,18,144:6:0 +X 2638 . T <*> 0 . DP=24;I16=19,5,0,0,821,28851,0,0,1409,83641,0,0,428,9588,0,0;QS=3,0;MQSB=0.984335;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,103:3:0 0,18,135:6:0 +X 2639 . G <*> 0 . DP=24;I16=18,6,0,0,842,30840,0,0,1409,83641,0,0,428,9582,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,106:3:0 0,15,125:5:0 +X 2640 . G <*> 0 . DP=24;I16=17,6,0,0,749,25957,0,0,1380,82800,0,0,404,8976,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,84:3:0 0,15,117:5:0 +X 2641 . C <*> 0 . DP=23;I16=17,6,0,0,834,31792,0,0,1349,80041,0,0,431,9645,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,61:2:0 0,15,129:5:0 +X 2642 . C <*> 0 . DP=23;I16=17,6,0,0,809,30033,0,0,1349,80041,0,0,433,9713,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,58:2:0 0,15,131:5:0 +X 2643 . C <*> 0 . DP=23;I16=17,6,0,0,856,33004,0,0,1349,80041,0,0,434,9756,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,57:2:0 0,15,133:5:0 +X 2644 . T <*> 0 . DP=22;I16=16,5,0,0,805,31419,0,0,1229,72841,0,0,428,9648,0,0;QS=3,0;MQSB=0.978919;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,73:2:0 0,15,143:5:0 +X 2645 . C <*> 0 . DP=22;I16=15,6,0,0,823,32499,0,0,1229,72841,0,0,415,9323,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,78:2:0 0,12,122:4:0 +X 2646 . A <*> 0 . DP=22;I16=16,6,0,0,826,31566,0,0,1289,76441,0,0,430,9524,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,79:2:0 0,15,129:5:0 +X 2647 . G <*> 0 . DP=22;I16=16,6,0,0,803,30643,0,0,1289,76441,0,0,428,9460,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,77:2:0 0,15,129:5:0 +X 2648 . C <*> 0 . DP=21;I16=15,6,0,0,811,31709,0,0,1229,72841,0,0,426,9368,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,80:2:0 0,12,118:4:0 +X 2649 . A <*> 0 . DP=23;I16=16,6,0,0,789,29215,0,0,1258,73682,0,0,414,9196,0,0;QS=3,0;MQSB=0.934321;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,93:3:0 0,12,105:4:0 +X 2650 . T <*> 0 . DP=23;I16=16,7,0,0,856,32340,0,0,1318,77282,0,0,423,9197,0,0;QS=3,0;MQSB=0.955805;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,103:3:0 0,12,118:4:0 +X 2651 . C <*> 0 . DP=23;I16=16,7,0,0,871,33599,0,0,1318,77282,0,0,422,9124,0,0;QS=3,0;MQSB=0.955805;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,95:3:0 0,12,121:4:0 +X 2652 . A <*> 0 . DP=23;I16=16,7,0,0,820,30324,0,0,1318,77282,0,0,421,9077,0,0;QS=3,0;MQSB=0.955805;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,87:3:0 0,12,126:4:0 +X 2653 . A <*> 0 . DP=23;I16=15,6,0,0,759,28489,0,0,1198,70082,0,0,389,8395,0,0;QS=3,0;MQSB=0.940481;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,73:2:0 0,9,109:3:0 +X 2654 . C <*> 0 . DP=23;I16=16,7,0,0,836,31006,0,0,1318,77282,0,0,393,8385,0,0;QS=3,0;MQSB=0.955805;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,88:3:0 0,9,99:3:0 +X 2655 . C <*> 0 . DP=23;I16=16,7,0,0,774,27190,0,0,1318,77282,0,0,392,8364,0,0;QS=3,0;MQSB=0.955805;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,83:3:0 0,9,95:3:0 +X 2656 . G <*> 0 . DP=24;I16=17,7,0,0,781,25689,0,0,1378,80882,0,0,390,8320,0,0;QS=3,0;MQSB=0.95083;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,116:4:0 0,9,74:3:0 +X 2657 . C <*> 0 . DP=24;I16=17,6,0,0,871,33435,0,0,1349,80041,0,0,381,8241,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,98:3:0 0,9,99:3:0 +X 2658 . T <*> 0 . DP=23;I16=17,6,0,0,897,35255,0,0,1318,77282,0,0,389,8319,0,0;QS=3,0;MQSB=0.92854;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,133:4:0 0,9,107:3:0 +X 2659 . A <*> 0 . DP=23;I16=17,6,0,0,817,29729,0,0,1318,77282,0,0,389,8361,0,0;QS=3,0;MQSB=0.92854;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,120:4:0 0,9,93:3:0 +X 2660 . G <*> 0 . DP=23;I16=17,6,0,0,900,35462,0,0,1318,77282,0,0,389,8379,0,0;QS=3,0;MQSB=0.92854;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,126:4:0 0,9,94:3:0 +X 2661 . A <*> 0 . DP=24;I16=18,6,0,0,871,32185,0,0,1378,80882,0,0,390,8422,0,0;QS=3,0;MQSB=0.923116;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,127:4:0 0,9,104:3:0 +X 2662 . T <*> 0 . DP=24;I16=17,6,0,0,836,30812,0,0,1349,80041,0,0,366,7816,0,0;QS=3,0;MQSB=0.83771;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,122:4:0 0,9,99:3:0 +X 2663 . A <*> 0 . DP=24;I16=17,6,0,0,827,30583,0,0,1318,77282,0,0,389,8341,0,0;QS=3,0;MQSB=0.92854;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,104:4:0 0,9,101:3:0 +X 2664 . C <*> 0 . DP=23;I16=17,6,0,0,787,28083,0,0,1318,77282,0,0,388,8270,0,0;QS=3,0;MQSB=0.92854;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,107:4:0 0,9,91:3:0 +X 2665 . G <*> 0 . DP=23;I16=17,6,0,0,728,23290,0,0,1318,77282,0,0,386,8178,0,0;QS=3,0;MQSB=0.92854;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,112:4:0 0,9,78:3:0 +X 2666 . T <*> 0 . DP=23;I16=17,5,0,0,799,29273,0,0,1289,76441,0,0,367,7825,0,0;QS=3,0;MQSB=0.981001;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,105:3:0 0,9,94:3:0 +X 2667 . C <*> 0 . DP=23;I16=16,5,0,0,792,30190,0,0,1260,75600,0,0,345,7393,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,96:3:0 0,9,98:3:0 +X 2668 . C <*> 0 . DP=24;I16=18,6,0,0,832,29692,0,0,1378,80882,0,0,381,8069,0,0;QS=3,0;MQSB=0.923116;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,107:4:0 0,9,95:3:0 +X 2669 . C <*> 0 . DP=23;I16=18,5,0,0,829,30953,0,0,1318,77282,0,0,383,8087,0,0;QS=3,0;MQSB=0.889264;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,120:4:0 0,9,88:3:0 +X 2670 . T <*> 0 . DP=23;I16=17,5,0,0,841,32669,0,0,1289,76441,0,0,368,7828,0,0;QS=3,0;MQSB=0.801124;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,131:4:0 0,9,100:3:0 +X 2671 . C <*> 0 . DP=22;I16=17,5,0,0,842,32448,0,0,1258,73682,0,0,386,8110,0,0;QS=3,0;MQSB=0.895399;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,128:4:0 0,6,70:2:0 +X 2672 . C <*> 0 . DP=22;I16=17,5,0,0,808,30180,0,0,1258,73682,0,0,388,8164,0,0;QS=3,0;MQSB=0.895399;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,129:4:0 0,6,75:2:0 +X 2673 . C <*> 0 . DP=22;I16=17,5,0,0,842,32528,0,0,1258,73682,0,0,390,8246,0,0;QS=3,0;MQSB=0.895399;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,133:4:0 0,6,75:2:0 +X 2674 . T <*> 0 . DP=23;I16=17,6,0,0,860,33242,0,0,1318,77282,0,0,392,8356,0,0;QS=3,0;MQSB=0.92854;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,142:4:0 0,6,79:2:0 +X 2675 . T <*> 0 . DP=22;I16=16,6,0,0,756,26986,0,0,1258,73682,0,0,394,8392,0,0;QS=3,0;MQSB=0.934321;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,134:4:0 0,6,74:2:0 +X 2676 . T <*> 0 . DP=22;I16=16,6,0,0,774,28022,0,0,1258,73682,0,0,396,8452,0,0;QS=3,0;MQSB=0.934321;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,135:4:0 0,6,75:2:0 +X 2677 . C <*> 0 . DP=22;I16=16,6,0,0,866,34444,0,0,1258,73682,0,0,398,8536,0,0;QS=3,0;MQSB=0.934321;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,131:4:0 0,6,77:2:0 +X 2678 . T <*> 0 . DP=22;I16=16,5,0,0,818,32216,0,0,1229,72841,0,0,374,7970,0,0;QS=3,0;MQSB=0.978919;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,111:3:0 0,6,80:2:0 +X 2679 . T <*> 0 . DP=22;I16=16,6,0,0,808,29912,0,0,1258,73682,0,0,400,8680,0,0;QS=3,0;MQSB=0.934321;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,137:4:0 0,6,75:2:0 +X 2680 . C <*> 0 . DP=23;I16=16,7,0,0,873,33605,0,0,1318,77282,0,0,400,8740,0,0;QS=3,0;MQSB=0.955805;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,131:4:0 0,6,70:2:0 +X 2681 . T <*> 0 . DP=22;I16=15,7,0,0,820,31248,0,0,1258,73682,0,0,402,8824,0,0;QS=3,0;MQSB=0.961028;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,133:4:0 0,6,75:2:0 +X 2682 . G <*> 0 . DP=22;I16=15,7,0,0,831,31865,0,0,1258,73682,0,0,403,8881,0,0;QS=3,0;MQSB=0.961028;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,135:4:0 0,6,64:2:0 +X 2683 . G <*> 0 . DP=22;I16=13,6,0,0,702,26368,0,0,1109,65641,0,0,394,8926,0,0;QS=3,0;MQSB=0.850016;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,136:4:0 0,6,53:2:0 +X 2684 . G <*> 0 . DP=22;I16=14,7,0,0,754,27678,0,0,1229,72841,0,0,403,9057,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,128:4:0 0,6,62:2:0 +X 2685 . G <*> 0 . DP=22;I16=15,7,0,0,736,25916,0,0,1258,73682,0,0,406,9184,0,0;QS=3,0;MQSB=0.961028;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,130:4:0 0,6,45:2:0 +X 2686 . C <*> 0 . DP=22;I16=15,7,0,0,803,29933,0,0,1258,73682,0,0,406,9278,0,0;QS=3,0;MQSB=0.961028;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,134:4:0 0,6,68:2:0 +X 2687 . A <*> 0 . DP=21;I16=13,7,0,0,716,26356,0,0,1169,69241,0,0,406,9340,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,136:4:0 0,6,61:2:0 +X 2688 . C <*> 0 . DP=20;I16=13,7,0,0,750,28308,0,0,1169,69241,0,0,407,9417,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,134:4:0 0,6,66:2:0 +X 2689 . A <*> 0 . DP=19;I16=12,7,0,0,741,29105,0,0,1109,65641,0,0,409,9507,0,0;QS=3,0;MQSB=0.879351;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,140:4:0 0,6,73:2:0 +X 2690 . G <*> 0 . DP=20;I16=12,8,0,0,751,28929,0,0,1169,69241,0,0,411,9609,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,135:4:0 0,6,61:2:0 +X 2691 . G <*> 0 . DP=20;I16=12,7,0,0,682,25006,0,0,1109,65641,0,0,403,9603,0,0;QS=3,0;MQSB=0.879351;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,132:4:0 0,6,63:2:0 +X 2692 . T <*> 0 . DP=20;I16=12,8,0,0,648,21758,0,0,1169,69241,0,0,417,9853,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,125:4:0 0,6,72:2:0 +X 2693 . C <*> 0 . DP=20;I16=12,8,0,0,779,30645,0,0,1169,69241,0,0,418,9898,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,130:4:0 0,6,70:2:0 +X 2694 . A <*> 0 . DP=21;I16=13,8,0,0,723,25649,0,0,1229,72841,0,0,417,9859,0,0;QS=3,0;MQSB=0.895122;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,126:4:0 0,6,73:2:0 +X 2695 . C <*> 0 . DP=20;I16=12,8,0,0,757,28835,0,0,1169,69241,0,0,418,9834,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,130:4:0 0,6,63:2:0 +X 2696 . A <*> 0 . DP=20;I16=12,8,0,0,733,27357,0,0,1169,69241,0,0,419,9823,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,130:4:0 0,6,69:2:0 +X 2697 . C <*> 0 . DP=20;I16=12,8,0,0,738,27604,0,0,1169,69241,0,0,419,9777,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,128:4:0 0,6,66:2:0 +X 2698 . T <*> 0 . DP=21;I16=12,8,0,0,788,31268,0,0,1169,69241,0,0,419,9747,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,144:4:0 0,6,77:2:0 +X 2699 . C <*> 0 . DP=22;I16=13,9,0,0,864,34148,0,0,1258,73682,0,0,443,10309,0,0;QS=3,0;MQSB=0.686045;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,135:4:0 0,9,98:3:0 +X 2700 . T <*> 0 . DP=22;I16=13,9,0,0,850,33296,0,0,1258,73682,0,0,444,10310,0,0;QS=3,0;MQSB=0.686045;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,141:4:0 0,9,105:3:0 +X 2701 . C <*> 0 . DP=22;I16=13,9,0,0,863,34157,0,0,1258,73682,0,0,444,10278,0,0;QS=3,0;MQSB=0.686045;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,140:4:0 0,9,94:3:0 +X 2702 . T <*> 0 . DP=22;I16=13,9,0,0,837,32525,0,0,1258,73682,0,0,444,10262,0,0;QS=3,0;MQSB=0.686045;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,143:4:0 0,9,83:3:0 +X 2703 . T <*> 0 . DP=21;I16=12,8,0,0,717,25881,0,0,1169,69241,0,0,420,9636,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,130:4:0 0,3,32:1:0 +X 2704 . C <*> 0 . DP=21;I16=12,9,0,0,794,30766,0,0,1198,70082,0,0,445,10225,0,0;QS=3,0;MQSB=0.695144;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,137:4:0 0,6,55:2:0 +X 2705 . C <*> 0 . DP=21;I16=12,9,0,0,809,31649,0,0,1198,70082,0,0,445,10205,0,0;QS=3,0;MQSB=0.695144;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,136:4:0 0,6,56:2:0 +X 2706 . A <*> 0 . DP=22;I16=12,10,0,0,820,31386,0,0,1258,73682,0,0,444,10150,0,0;QS=3,0;MQSB=0.731218;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,141:4:0 0,6,70:2:0 +X 2707 . G <*> 0 . DP=22;I16=12,10,0,0,832,32104,0,0,1258,73682,0,0,444,10110,0,0;QS=3,0;MQSB=0.731218;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,139:4:0 0,6,60:2:0 +X 2708 . G <*> 0 . DP=22;I16=12,10,0,0,777,28329,0,0,1258,73682,0,0,444,10086,0,0;QS=3,0;MQSB=0.731218;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,136:4:0 0,6,57:2:0 +X 2709 . T <*> 0 . DP=22;I16=12,9,0,0,761,28341,0,0,1229,72841,0,0,418,9404,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,137:4:0 0,3,39:1:0 +X 2710 . C <*> 0 . DP=23;I16=12,10,0,0,840,32478,0,0,1289,76441,0,0,417,9365,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,134:4:0 0,3,38:1:0 +X 2711 . T <*> 0 . DP=24;I16=13,11,0,0,893,33721,0,0,1378,80882,0,0,442,9970,0,0;QS=3,0;MQSB=0.75304;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,138:4:0 0,6,72:2:0 +X 2712 . A <*> 0 . DP=24;I16=13,11,0,0,889,33333,0,0,1378,80882,0,0,443,9971,0,0;QS=3,0;MQSB=0.75304;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,141:4:0 0,6,65:2:0 +X 2713 . G T,<*> 0 . DP=25;I16=13,11,0,1,915,35485,14,196,1378,80882,29,841,419,9369,25,625;QS=2.72549,0.27451,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.569783;BQB=1;MQ0F=0 PL:DP:DV 0,57,255,57,255,255:19:0 0,12,131,12,131,131:4:0 8,0,31,11,34,42:2:1 +X 2714 . G <*> 0 . DP=25;I16=13,11,0,0,891,33457,0,0,1378,80882,0,0,444,9990,0,0;QS=3,0;MQSB=0.75304;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,132:4:0 0,6,64:2:0 +X 2715 . A <*> 0 . DP=25;I16=13,12,0,0,888,32012,0,0,1407,81723,0,0,446,10014,0,0;QS=3,0;MQSB=0.569783;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,12,135:4:0 0,6,63:2:0 +X 2716 . T <*> 0 . DP=26;I16=13,13,0,0,937,34241,0,0,1467,85323,0,0,446,10012,0,0;QS=3,0;MQSB=0.606531;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,12,134:4:0 0,9,90:3:0 +X 2717 . G <*> 0 . DP=26;I16=13,12,0,0,939,35995,0,0,1438,84482,0,0,422,9410,0,0;QS=3,0;MQSB=0.778801;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,12,134:4:0 0,6,72:2:0 +X 2718 . C <*> 0 . DP=24;I16=12,11,0,0,864,33118,0,0,1318,77282,0,0,425,9457,0,0;QS=3,0;MQSB=0.7613;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,130:4:0 0,6,65:2:0 +X 2719 . A <*> 0 . DP=24;I16=12,12,0,0,911,35371,0,0,1347,78123,0,0,452,10102,0,0;QS=3,0;MQSB=0.582748;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,139:4:0 0,9,99:3:0 +X 2720 . G <*> 0 . DP=24;I16=12,12,0,0,940,37044,0,0,1347,78123,0,0,453,10095,0,0;QS=3,0;MQSB=0.582748;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,136:4:0 0,9,97:3:0 +X 2721 . C <*> 0 . DP=24;I16=12,11,0,0,881,34499,0,0,1318,77282,0,0,429,9485,0,0;QS=3,0;MQSB=0.7613;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,131:4:0 0,6,76:2:0 +X 2722 . T <*> 0 . DP=24;I16=11,13,0,0,898,34310,0,0,1347,78123,0,0,456,10146,0,0;QS=3,0;MQSB=0.633229;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,156:5:0 0,9,98:3:0 +X 2723 . G <*> 0 . DP=25;I16=12,13,0,0,941,36257,0,0,1407,81723,0,0,459,10203,0,0;QS=3,0;MQSB=0.619223;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,184:6:0 0,9,76:3:0 +X 2724 . A <*> 0 . DP=25;I16=12,13,0,0,917,34211,0,0,1407,81723,0,0,462,10234,0,0;QS=3,0;MQSB=0.619223;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,188:6:0 0,9,84:3:0 +X 2725 . G <*> 0 . DP=25;I16=12,12,0,0,916,35656,0,0,1378,80882,0,0,438,9566,0,0;QS=3,0;MQSB=0.786628;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,185:6:0 0,6,67:2:0 +X 2726 . G <*> 0 . DP=25;I16=11,12,0,0,841,31809,0,0,1287,74523,0,0,437,9545,0,0;QS=3,0;MQSB=0.597127;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,186:6:0 0,6,46:2:0 +X 2727 . G <*> 0 . DP=25;I16=12,13,0,0,889,32233,0,0,1407,81723,0,0,464,10182,0,0;QS=3,0;MQSB=0.619223;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,194:7:0 0,6,56:2:0 +X 2728 . G <*> 0 . DP=25;I16=12,13,0,0,883,32287,0,0,1407,81723,0,0,467,10219,0,0;QS=3,0;MQSB=0.619223;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,189:7:0 0,6,50:2:0 +X 2729 . T <*> 0 . DP=25;I16=12,13,0,0,871,31019,0,0,1407,81723,0,0,469,10233,0,0;QS=3,0;MQSB=0.619223;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,189:7:0 0,6,62:2:0 +X 2730 . G <*> 0 . DP=25;I16=12,13,0,0,907,34299,0,0,1407,81723,0,0,471,10275,0,0;QS=3,0;MQSB=0.619223;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,192:7:0 0,6,49:2:0 +X 2731 . C <*> 0 . DP=25;I16=12,13,0,0,893,33027,0,0,1407,81723,0,0,473,10345,0,0;QS=3,0;MQSB=0.619223;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,192:7:0 0,6,52:2:0 +X 2732 . C <*> 0 . DP=25;I16=12,13,0,0,882,32170,0,0,1407,81723,0,0,473,10343,0,0;QS=3,0;MQSB=0.619223;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,195:7:0 0,6,38:2:0 +X 2733 . C A,<*> 0 . DP=25;I16=12,12,0,1,835,30063,13,169,1378,80882,29,841,448,9744,25,625;QS=2.64865,0.351351,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.619223;BQB=1;MQ0F=0 PL:DP:DV 0,48,255,48,255,255:16:0 0,21,187,21,187,187:7:0 7,0,18,10,21,28:2:1 +X 2734 . C <*> 0 . DP=25;I16=12,12,0,0,890,33726,0,0,1378,80882,0,0,449,9797,0,0;QS=3,0;MQSB=0.786628;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,208:8:0 0,3,39:1:0 +X 2735 . T <*> 0 . DP=26;I16=13,12,0,0,955,36875,0,0,1438,84482,0,0,451,9877,0,0;QS=3,0;MQSB=0.778801;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,228:8:0 0,3,41:1:0 +X 2736 . C <*> 0 . DP=26;I16=13,11,0,0,921,35553,0,0,1409,83641,0,0,428,9308,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,220:8:0 0,3,33:1:0 +X 2737 . T <*> 0 . DP=26;I16=13,13,0,0,967,36581,0,0,1467,85323,0,0,475,10403,0,0;QS=3,0;MQSB=0.606531;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,228:8:0 0,6,64:2:0 +X 2738 . T <*> 0 . DP=26;I16=13,13,0,0,895,31873,0,0,1467,85323,0,0,474,10374,0,0;QS=3,0;MQSB=0.606531;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,201:8:0 0,6,47:2:0 +X 2739 . A <*> 0 . DP=26;I16=13,12,0,0,871,31051,0,0,1407,81723,0,0,448,9698,0,0;QS=3,0;MQSB=0.569783;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,224:8:0 0,9,78:3:0 +X 2740 . C <*> 0 . DP=26;I16=14,11,0,0,952,36456,0,0,1438,84482,0,0,448,9674,0,0;QS=3,0;MQSB=0.745495;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,216:8:0 0,6,71:2:0 +X 2741 . C <*> 0 . DP=26;I16=14,11,0,0,945,36141,0,0,1438,84482,0,0,448,9678,0,0;QS=3,0;MQSB=0.745495;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,215:8:0 0,6,75:2:0 +X 2742 . A <*> 0 . DP=27;I16=15,12,0,0,949,34263,0,0,1527,88923,0,0,472,10284,0,0;QS=3,0;MQSB=0.547344;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,230:9:0 0,9,92:3:0 +X 2743 . T <*> 0 . DP=27;I16=15,12,0,0,955,34479,0,0,1527,88923,0,0,471,10243,0,0;QS=3,0;MQSB=0.547344;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,224:9:0 0,9,99:3:0 +X 2744 . C <*> 0 . DP=26;I16=15,10,0,0,955,36951,0,0,1438,84482,0,0,445,9557,0,0;QS=3,0;MQSB=0.707404;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,234:9:0 0,6,76:2:0 +X 2745 . T <*> 0 . DP=26;I16=15,11,0,0,962,36786,0,0,1467,85323,0,0,469,10151,0,0;QS=3,0;MQSB=0.505697;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,243:9:0 0,9,104:3:0 +X 2746 . A <*> 0 . DP=26;I16=15,10,0,0,912,33536,0,0,1438,84482,0,0,443,9525,0,0;QS=3,0;MQSB=0.707404;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,235:9:0 0,6,78:2:0 +X 2747 . A <*> 0 . DP=26;I16=15,11,0,0,945,35117,0,0,1467,85323,0,0,467,10179,0,0;QS=3,0;MQSB=0.505697;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,238:9:0 0,9,96:3:0 +X 2748 . T <*> 0 . DP=27;I16=15,12,0,0,1005,37901,0,0,1527,88923,0,0,465,10187,0,0;QS=3,0;MQSB=0.547344;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,246:9:0 0,9,103:3:0 +X 2749 . C <*> 0 . DP=26;I16=14,12,0,0,975,37353,0,0,1467,85323,0,0,463,10123,0,0;QS=3,0;MQSB=0.558035;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,232:9:0 0,9,98:3:0 +X 2750 . T <*> 0 . DP=26;I16=15,11,0,0,982,37714,0,0,1498,88082,0,0,462,10086,0,0;QS=3,0;MQSB=0.738577;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,227:8:0 0,12,130:4:0 +X 2751 . G <*> 0 . DP=26;I16=15,10,0,0,945,36031,0,0,1469,87241,0,0,437,9451,0,0;QS=3,0;MQSB=0.9171;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,205:8:0 0,9,103:3:0 +X 2752 . T <*> 0 . DP=26;I16=15,11,0,0,870,30288,0,0,1498,88082,0,0,460,9998,0,0;QS=3,0;MQSB=0.738577;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,189:8:0 0,12,119:4:0 +X 2753 . G <*> 0 . DP=26;I16=15,11,0,0,867,30913,0,0,1498,88082,0,0,458,9948,0,0;QS=3,0;MQSB=0.738577;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,202:8:0 0,12,116:4:0 +X 2754 . C <*> 0 . DP=25;I16=14,10,0,0,873,32607,0,0,1409,83641,0,0,436,9484,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,205:8:0 0,9,104:3:0 +X 2755 . C <*> 0 . DP=25;I16=14,10,0,0,865,32243,0,0,1409,83641,0,0,436,9528,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,209:8:0 0,9,97:3:0 +X 2756 . C <*> 0 . DP=25;I16=14,9,0,0,838,31276,0,0,1380,82800,0,0,411,8971,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,204:8:0 0,9,97:3:0 +X 2757 . T <*> 0 . DP=25;I16=14,11,0,0,904,33980,0,0,1438,84482,0,0,455,10011,0,0;QS=3,0;MQSB=0.745495;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,212:7:0 0,15,147:5:0 +X 2758 . T <*> 0 . DP=25;I16=14,10,0,0,841,30293,0,0,1409,83641,0,0,439,9801,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,195:7:0 0,12,133:4:0 +X 2759 . A <*> 0 . DP=25;I16=14,11,0,0,884,31728,0,0,1438,84482,0,0,457,10195,0,0;QS=3,0;MQSB=0.745495;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,192:7:0 0,15,147:5:0 +X 2760 . T <*> 0 . DP=25;I16=14,11,0,0,907,33965,0,0,1438,84482,0,0,457,10275,0,0;QS=3,0;MQSB=0.745495;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,204:7:0 0,15,150:5:0 +X 2761 . T <*> 0 . DP=23;I16=13,9,0,0,838,32530,0,0,1289,76441,0,0,444,10130,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,185:6:0 0,12,141:4:0 +X 2762 . T <*> 0 . DP=24;I16=13,11,0,0,869,32261,0,0,1378,80882,0,0,459,10395,0,0;QS=3,0;MQSB=0.75304;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,178:6:0 0,18,177:6:0 +X 2763 . C A,<*> 0 . DP=24;I16=13,10,0,1,843,31711,13,169,1349,80041,29,841,448,10290,12,144;QS=2.93333,0.0666667,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.75304;BQB=1;MQ0F=0 PL:DP:DV 0,36,255,36,255,255:12:0 0,18,170,18,170,170:6:0 0,5,147,15,150,153:6:1 +X 2764 . C <*> 0 . DP=24;I16=13,10,0,0,854,32376,0,0,1349,80041,0,0,450,10374,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,163:6:0 0,15,162:5:0 +X 2765 . T <*> 0 . DP=24;I16=12,11,0,0,853,32173,0,0,1318,77282,0,0,457,10469,0,0;QS=3,0;MQSB=0.7613;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,154:5:0 0,18,189:6:0 +X 2766 . C <*> 0 . DP=24;I16=12,11,0,0,887,34485,0,0,1349,80041,0,0,448,10398,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,160:5:0 0,18,186:6:0 +X 2767 . T <*> 0 . DP=24;I16=12,12,0,0,905,34757,0,0,1378,80882,0,0,458,10510,0,0;QS=3,0;MQSB=0.786628;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,153:5:0 0,21,217:7:0 +X 2768 . G <*> 0 . DP=23;I16=11,11,0,0,852,33258,0,0,1289,76441,0,0,452,10462,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,141:5:0 0,18,197:6:0 +X 2769 . C <*> 0 . DP=23;I16=11,12,0,0,832,31390,0,0,1318,77282,0,0,459,10481,0,0;QS=3,0;MQSB=0.795196;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,142:5:0 0,21,202:7:0 +X 2770 . T <*> 0 . DP=23;I16=11,12,0,0,828,30854,0,0,1318,77282,0,0,459,10471,0,0;QS=3,0;MQSB=0.795196;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,152:5:0 0,21,199:7:0 +X 2771 . T <*> 0 . DP=23;I16=11,11,0,0,817,30957,0,0,1258,73682,0,0,454,10456,0,0;QS=3,0;MQSB=0.770381;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,154:5:0 0,18,198:6:0 +X 2772 . T <*> 0 . DP=23;I16=11,12,0,0,856,32206,0,0,1318,77282,0,0,459,10511,0,0;QS=3,0;MQSB=0.795196;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,160:5:0 0,21,210:7:0 +X 2773 . A <*> 0 . DP=23;I16=11,12,0,0,828,30664,0,0,1318,77282,0,0,459,10561,0,0;QS=3,0;MQSB=0.795196;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,140:5:0 0,21,209:7:0 +X 2774 . G <*> 0 . DP=22;I16=11,11,0,0,843,32715,0,0,1258,73682,0,0,458,10530,0,0;QS=3,0;MQSB=0.770381;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,154:5:0 0,21,207:7:0 +X 2775 . T <*> 0 . DP=22;I16=10,11,0,0,748,27720,0,0,1198,70082,0,0,432,9892,0,0;QS=3,0;MQSB=0.780412;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,12,115:4:0 0,21,203:7:0 +X 2776 . G <*> 0 . DP=22;I16=12,10,0,0,803,30251,0,0,1289,76441,0,0,456,10470,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,135:5:0 0,21,210:7:0 +X 2777 . A <*> 0 . DP=22;I16=12,10,0,0,852,33524,0,0,1289,76441,0,0,456,10438,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,148:5:0 0,21,220:7:0 +X 2778 . G <*> 0 . DP=23;I16=12,11,0,0,861,33049,0,0,1349,80041,0,0,456,10422,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,154:5:0 0,21,224:7:0 +X 2779 . G <*> 0 . DP=23;I16=11,11,0,0,834,32014,0,0,1289,76441,0,0,432,9798,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,136:4:0 0,21,219:7:0 +X 2780 . A <*> 0 . DP=23;I16=11,11,0,0,792,29162,0,0,1289,76441,0,0,433,9817,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,33,244:11:0 0,12,133:4:0 0,21,215:7:0 +X 2781 . A <*> 0 . DP=23;I16=11,11,0,0,844,33092,0,0,1289,76441,0,0,441,10141,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,15,151:5:0 0,21,233:7:0 +X 2782 . G <*> 0 . DP=23;I16=12,11,0,0,840,31826,0,0,1349,80041,0,0,458,10438,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,154:5:0 0,21,218:7:0 +X 2783 . A <*> 0 . DP=23;I16=11,11,0,0,860,33888,0,0,1289,76441,0,0,432,9790,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,142:4:0 0,21,230:7:0 +X 2784 . G <*> 0 . DP=23;I16=12,11,0,0,860,33092,0,0,1349,80041,0,0,456,10410,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,143:5:0 0,21,212:7:0 +X 2785 . G <*> 0 . DP=23;I16=11,11,0,0,797,29747,0,0,1289,76441,0,0,429,9749,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,134:4:0 0,21,204:7:0 +X 2786 . C <*> 0 . DP=24;I16=12,12,0,0,831,29497,0,0,1409,83641,0,0,451,10309,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,141:5:0 0,21,199:7:0 +X 2787 . C <*> 0 . DP=24;I16=11,12,0,0,792,28454,0,0,1349,80041,0,0,424,9642,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,36,252:12:0 0,12,127:4:0 0,21,200:7:0 +X 2788 . C <*> 0 . DP=23;I16=11,11,0,0,791,29517,0,0,1289,76441,0,0,421,9523,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,125:4:0 0,21,209:7:0 +X 2789 . C <*> 0 . DP=24;I16=13,11,0,0,880,33470,0,0,1409,83641,0,0,443,10051,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,150:5:0 0,21,226:7:0 +X 2790 . T <*> 0 . DP=23;I16=13,10,0,0,886,34738,0,0,1349,80041,0,0,442,9976,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,165:5:0 0,21,227:7:0 +X 2791 . G <*> 0 . DP=23;I16=13,10,0,0,873,34037,0,0,1349,80041,0,0,441,9923,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,155:5:0 0,21,226:7:0 +X 2792 . G <*> 0 . DP=23;I16=13,10,0,0,832,30870,0,0,1349,80041,0,0,438,9792,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,15,146:5:0 0,21,221:7:0 +X 2793 . T <*> 0 . DP=23;I16=13,10,0,0,827,30693,0,0,1349,80041,0,0,435,9683,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,33,247:11:0 0,15,157:5:0 0,21,214:7:0 +X 2794 . C <*> 0 . DP=22;I16=12,10,0,0,786,29122,0,0,1289,76441,0,0,433,9595,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,145:5:0 0,21,201:7:0 +X 2795 . C <*> 0 . DP=22;I16=11,10,0,0,814,31804,0,0,1229,72841,0,0,428,9518,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,15,159:5:0 0,21,222:7:0 +X 2796 . A <*> 0 . DP=22;I16=11,10,0,0,762,28412,0,0,1229,72841,0,0,427,9475,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,27,221:9:0 0,15,156:5:0 0,21,211:7:0 +X 2797 . T <*> 0 . DP=22;I16=12,10,0,0,792,29116,0,0,1289,76441,0,0,427,9451,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,15,148:5:0 0,21,214:7:0 +X 2798 . G <*> 0 . DP=22;I16=12,10,0,0,817,31105,0,0,1289,76441,0,0,424,9394,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,152:5:0 0,21,205:7:0 +X 2799 . A <*> 0 . DP=21;I16=11,10,0,0,788,30210,0,0,1229,72841,0,0,421,9309,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,27,220:9:0 0,15,167:5:0 0,21,218:7:0 +X 2800 . A <*> 0 . DP=21;I16=11,10,0,0,836,33616,0,0,1229,72841,0,0,418,9246,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,27,237:9:0 0,15,164:5:0 0,21,237:7:0 +X 2801 . G <*> 0 . DP=21;I16=11,10,0,0,792,30182,0,0,1229,72841,0,0,415,9205,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,27,234:9:0 0,15,157:5:0 0,21,214:7:0 +X 2802 . G <*> 0 . DP=21;I16=11,9,0,0,729,27275,0,0,1169,69241,0,0,387,8559,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,24,229:8:0 0,15,135:5:0 0,21,215:7:0 +X 2803 . G <*> 0 . DP=21;I16=11,10,0,0,737,26709,0,0,1229,72841,0,0,406,9036,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,15,125:5:0 0,21,207:7:0 +X 2804 . G <*> 0 . DP=21;I16=11,10,0,0,727,26103,0,0,1229,72841,0,0,400,8908,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,27,218:9:0 0,15,129:5:0 0,21,210:7:0 +X 2805 . C <*> 0 . DP=21;I16=10,10,0,0,714,26194,0,0,1169,69241,0,0,372,8316,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,27,229:9:0 0,12,111:4:0 0,21,205:7:0 +X 2806 . C <*> 0 . DP=20;I16=11,8,0,0,682,25074,0,0,1109,65641,0,0,379,8611,0,0;QS=3,0;MQSB=0.902014;MQ0F=0 PL:DP:DV 0,24,215:8:0 0,15,138:5:0 0,18,191:6:0 +X 2807 . T <*> 0 . DP=20;I16=11,9,0,0,755,29373,0,0,1169,69241,0,0,384,8640,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,15,152:5:0 0,21,227:7:0 +X 2808 . T <*> 0 . DP=20;I16=11,9,0,0,749,28383,0,0,1169,69241,0,0,379,8587,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,24,209:8:0 0,15,157:5:0 0,21,225:7:0 +X 2809 . T <*> 0 . DP=20;I16=11,8,0,0,697,26019,0,0,1109,65641,0,0,349,7927,0,0;QS=3,0;MQSB=0.902014;MQ0F=0 PL:DP:DV 0,21,189:7:0 0,15,148:5:0 0,21,226:7:0 +X 2810 . C <*> 0 . DP=20;I16=12,8,0,0,754,28900,0,0,1169,69241,0,0,368,8436,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,24,229:8:0 0,15,150:5:0 0,21,215:7:0 +X 2811 . A <*> 0 . DP=19;I16=11,8,0,0,759,30405,0,0,1109,65641,0,0,364,8340,0,0;QS=3,0;MQSB=0.902014;MQ0F=0 PL:DP:DV 0,21,209:7:0 0,15,166:5:0 0,21,228:7:0 +X 2812 . G <*> 0 . DP=20;I16=11,9,0,0,758,29062,0,0,1169,69241,0,0,359,8213,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,24,229:8:0 0,15,150:5:0 0,21,216:7:0 +X 2813 . A <*> 0 . DP=19;I16=11,8,0,0,702,27106,0,0,1140,68400,0,0,356,8104,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,195:7:0 0,15,160:5:0 0,21,217:7:0 +X 2814 . G <*> 0 . DP=19;I16=11,8,0,0,703,26579,0,0,1140,68400,0,0,353,8013,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,217:7:0 0,15,147:5:0 0,21,204:7:0 +X 2815 . A <*> 0 . DP=19;I16=10,7,0,0,597,21979,0,0,1020,61200,0,0,326,7470,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,170:6:0 0,12,122:4:0 0,21,208:7:0 +X 2816 . C <*> 0 . DP=19;I16=11,8,0,0,630,21880,0,0,1140,68400,0,0,343,7685,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,193:7:0 0,15,134:5:0 0,21,180:7:0 +X 2817 . G <*> 0 . DP=20;I16=11,8,0,0,612,20368,0,0,1140,68400,0,0,339,7547,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,200:7:0 0,15,115:5:0 0,21,178:7:0 +X 2818 . G <*> 0 . DP=20;I16=11,8,0,0,688,25280,0,0,1140,68400,0,0,335,7377,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,216:7:0 0,15,132:5:0 0,21,206:7:0 +X 2819 . G <*> 0 . DP=20;I16=11,8,0,0,696,25880,0,0,1140,68400,0,0,331,7227,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,222:7:0 0,15,142:5:0 0,21,195:7:0 +X 2820 . G <*> 0 . DP=20;I16=10,8,0,0,624,22228,0,0,1080,64800,0,0,320,7048,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,205:7:0 0,12,119:4:0 0,21,188:7:0 +X 2821 . A <*> 0 . DP=20;I16=9,7,0,0,496,16222,0,0,960,57600,0,0,279,6157,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,159:6:0 0,9,93:3:0 0,21,171:7:0 +X 2822 . C <*> 0 . DP=19;I16=8,9,0,0,543,18163,0,0,1020,61200,0,0,310,7064,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,203:7:0 0,9,79:3:0 0,21,168:7:0 +X 2823 . C <*> 0 . DP=18;I16=9,7,0,0,550,19506,0,0,960,57600,0,0,300,6640,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,201:7:0 0,6,58:2:0 0,21,192:7:0 +X 2824 . C <*> 0 . DP=18;I16=9,7,0,0,584,21560,0,0,960,57600,0,0,299,6567,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,219:8:0 0,3,37:1:0 0,21,210:7:0 +X 2825 . C <*> 0 . DP=18;I16=9,8,0,0,606,22286,0,0,1020,61200,0,0,324,7134,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,234:8:0 0,3,37:1:0 0,24,208:8:0 +X 2826 . T <*> 0 . DP=18;I16=9,8,0,0,604,21766,0,0,1020,61200,0,0,323,7043,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,222:8:0 0,3,33:1:0 0,24,220:8:0 +X 2827 . G <*> 0 . DP=18;I16=9,8,0,0,597,21643,0,0,1020,61200,0,0,322,6970,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,230:8:0 0,3,28:1:0 0,24,214:8:0 +X 2828 . A <*> 0 . DP=20;I16=9,9,0,0,598,20740,0,0,1080,64800,0,0,321,6915,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,213:9:0 0,3,36:1:0 0,24,219:8:0 +X 2829 . G <*> 0 . DP=20;I16=9,9,0,0,649,23719,0,0,1080,64800,0,0,305,6591,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,239:8:0 0,3,31:1:0 0,27,227:9:0 +X 2830 . G <*> 0 . DP=20;I16=9,10,0,0,661,23841,0,0,1140,68400,0,0,323,6867,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,248:9:0 0,3,34:1:0 0,27,222:9:0 +X 2831 . A <*> 0 . DP=21;I16=10,10,0,0,682,24052,0,0,1200,72000,0,0,324,6876,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,223:9:0 0,3,34:1:0 0,30,254:10:0 +X 2832 . G <*> 0 . DP=21;I16=10,8,0,0,626,22384,0,0,1080,64800,0,0,281,5883,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,230:8:0 0,3,31:1:0 0,27,223:9:0 +X 2833 . C <*> 0 . DP=21;I16=10,10,0,0,712,25708,0,0,1200,72000,0,0,327,6915,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,3,37:1:0 0,30,255:10:0 +X 2834 . C <*> 0 . DP=21;I16=10,9,0,0,674,24470,0,0,1140,68400,0,0,306,6464,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,230:8:0 0,3,36:1:0 0,30,243:10:0 +X 2835 . C <*> 0 . DP=20;I16=9,9,0,0,617,21835,0,0,1080,64800,0,0,305,6381,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,202:8:0 0,3,39:1:0 0,27,235:9:0 +X 2836 . C <*> 0 . DP=20;I16=9,9,0,0,580,19624,0,0,1080,64800,0,0,306,6412,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,206:8:0 0,3,39:1:0 0,27,200:9:0 +X 2837 . G <*> 0 . DP=21;I16=9,10,0,0,558,17614,0,0,1140,68400,0,0,330,7086,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,207:9:0 0,3,31:1:0 0,27,193:9:0 +X 2838 . A <*> 0 . DP=20;I16=9,10,0,0,640,22674,0,0,1140,68400,0,0,331,7065,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,245:9:0 0,3,17:1:0 0,27,220:9:0 +X 2839 . G <*> 0 . DP=20;I16=9,8,0,0,623,23267,0,0,1020,61200,0,0,282,5816,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,248:8:0 0,3,26:1:0 0,24,212:8:0 +X 2840 . C <*> 0 . DP=20;I16=9,10,0,0,644,22798,0,0,1140,68400,0,0,333,7089,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,3,32:1:0 0,27,227:9:0 +X 2841 . A <*> 0 . DP=20;I16=9,9,0,0,675,25801,0,0,1080,64800,0,0,309,6509,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,252:9:0 0,3,35:1:0 0,24,234:8:0 +X 2842 . G <*> 0 . DP=20;I16=9,10,0,0,688,25554,0,0,1140,68400,0,0,332,7056,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,3,31:1:0 0,27,233:9:0 +X 2843 . C <*> 0 . DP=20;I16=8,10,0,0,651,23969,0,0,1080,64800,0,0,309,6517,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,0,0:0:0 0,24,211:8:0 +X 2844 . A <*> 0 . DP=20;I16=8,11,0,0,685,25399,0,0,1140,68400,0,0,331,6969,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,0,0:0:0 0,27,231:9:0 +X 2845 . G <*> 0 . DP=20;I16=8,10,0,0,673,25399,0,0,1080,64800,0,0,311,6561,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,0,0:0:0 0,24,228:8:0 +X 2846 . C <*> 0 . DP=20;I16=8,10,0,0,617,22007,0,0,1080,64800,0,0,311,6577,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,0,0:0:0 0,24,218:8:0 +X 2847 . C <*> 0 . DP=20;I16=7,11,0,0,580,19468,0,0,1080,64800,0,0,321,6917,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,241:10:0 0,0,0:0:0 0,24,187:8:0 +X 2848 . G <*> 0 . DP=19;I16=7,10,0,0,542,17884,0,0,1020,61200,0,0,323,6999,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,218:9:0 0,0,0:0:0 0,24,191:8:0 +X 2849 . T <*> 0 . DP=19;I16=7,11,0,0,609,21717,0,0,1080,64800,0,0,341,7357,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,231:9:0 0,0,0:0:0 0,27,214:9:0 +X 2850 . C <*> 0 . DP=19;I16=7,11,0,0,574,18980,0,0,1080,64800,0,0,343,7461,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,234:9:0 0,0,0:0:0 0,27,188:9:0 +X 2851 . G <*> 0 . DP=17;I16=6,11,0,0,589,20831,0,0,1020,61200,0,0,346,7584,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,0,0:0:0 0,24,194:8:0 +X 2852 . T <*> 0 . DP=17;I16=6,11,0,0,625,23241,0,0,1020,61200,0,0,348,7676,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,0,0:0:0 0,24,214:8:0 +X 2853 . G <*> 0 . DP=17;I16=6,11,0,0,635,23949,0,0,1020,61200,0,0,349,7739,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,0,0:0:0 0,24,202:8:0 +X 2854 . T <*> 0 . DP=17;I16=6,11,0,0,602,21990,0,0,1020,61200,0,0,348,7722,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,0,0:0:0 0,24,207:8:0 +X 2855 . C <*> 0 . DP=17;I16=6,10,0,0,577,21539,0,0,960,57600,0,0,337,7623,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,0,0:0:0 0,21,185:7:0 +X 2856 . T <*> 0 . DP=17;I16=6,8,0,0,530,20570,0,0,840,50400,0,0,289,6507,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,252:9:0 0,0,0:0:0 0,15,167:5:0 +X 2857 . C <*> 0 . DP=18;I16=6,10,0,0,577,21641,0,0,960,57600,0,0,336,7664,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,0,0:0:0 0,21,185:7:0 +X 2858 . A <*> 0 . DP=19;I16=6,12,0,0,634,23006,0,0,1080,64800,0,0,355,8081,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,254:10:0 0,3,39:1:0 0,21,185:7:0 +X 2859 . C <*> 0 . DP=19;I16=6,13,0,0,646,23056,0,0,1140,68400,0,0,361,8139,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,3,26:1:0 0,24,194:8:0 +X 2860 . C <*> 0 . DP=19;I16=6,13,0,0,655,23687,0,0,1140,68400,0,0,360,8166,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,251:10:0 0,3,37:1:0 0,24,200:8:0 +X 2861 . C <*> 0 . DP=20;I16=7,12,0,0,708,26756,0,0,1140,68400,0,0,333,7537,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,38:1:0 0,21,203:7:0 +X 2862 . A <*> 0 . DP=20;I16=6,13,0,0,749,29753,0,0,1140,68400,0,0,332,7554,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,3,43:1:0 0,24,225:8:0 +X 2863 . G <*> 0 . DP=19;I16=7,12,0,0,707,26901,0,0,1140,68400,0,0,356,8166,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,35:1:0 0,21,195:7:0 +X 2864 . G <*> 0 . DP=19;I16=7,11,0,0,677,25833,0,0,1080,64800,0,0,352,8070,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,36:1:0 0,18,185:6:0 +X 2865 . G <*> 0 . DP=19;I16=7,12,0,0,671,24569,0,0,1140,68400,0,0,350,7994,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,27:1:0 0,21,193:7:0 +X 2866 . T <*> 0 . DP=18;I16=6,11,0,0,591,21071,0,0,1020,61200,0,0,338,7834,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,32:1:0 0,15,147:5:0 +X 2867 . G <*> 0 . DP=18;I16=7,11,0,0,655,24279,0,0,1080,64800,0,0,347,7889,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,58:2:0 0,15,150:5:0 +X 2868 . T <*> 0 . DP=18;I16=7,11,0,0,640,23702,0,0,1080,64800,0,0,347,7859,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,68:2:0 0,15,157:5:0 +X 2869 . C <*> 0 . DP=18;I16=7,11,0,0,655,24737,0,0,1080,64800,0,0,346,7794,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,56:2:0 0,15,165:5:0 +X 2870 . T <*> 0 . DP=18;I16=7,11,0,0,700,27480,0,0,1080,64800,0,0,345,7743,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,70:2:0 0,15,176:5:0 +X 2871 . G <*> 0 . DP=18;I16=7,11,0,0,700,27554,0,0,1080,64800,0,0,344,7706,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,68:2:0 0,15,172:5:0 +X 2872 . A <*> 0 . DP=18;I16=7,11,0,0,651,23869,0,0,1080,64800,0,0,343,7683,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,66:2:0 0,15,171:5:0 +X 2873 . A <*> 0 . DP=18;I16=7,11,0,0,664,25000,0,0,1080,64800,0,0,342,7674,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,61:2:0 0,15,159:5:0 +X 2874 . A <*> 0 . DP=18;I16=7,11,0,0,636,23286,0,0,1080,64800,0,0,341,7679,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,57:2:0 0,15,162:5:0 +X 2875 . C <*> 0 . DP=18;I16=7,11,0,0,664,25148,0,0,1080,64800,0,0,340,7698,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,63:2:0 0,15,166:5:0 +X 2876 . A <*> 0 . DP=18;I16=6,11,0,0,666,26684,0,0,1020,61200,0,0,314,7106,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,6,74:2:0 0,15,185:5:0 +X 2877 . G <*> 0 . DP=17;I16=6,11,0,0,659,26009,0,0,1020,61200,0,0,339,7777,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,67:2:0 0,12,148:4:0 +X 2878 . A <*> 0 . DP=17;I16=7,10,0,0,628,23656,0,0,1020,61200,0,0,340,7834,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,6,69:2:0 0,15,166:5:0 +X 2879 . T <*> 0 . DP=18;I16=7,11,0,0,671,25359,0,0,1080,64800,0,0,342,7902,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,9,96:3:0 0,15,175:5:0 +X 2880 . G <*> 0 . DP=19;I16=8,11,0,0,708,26694,0,0,1140,68400,0,0,345,7983,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,118:4:0 0,15,173:5:0 +X 2881 . T <*> 0 . DP=19;I16=6,11,0,0,618,23304,0,0,1020,61200,0,0,299,6829,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,209:8:0 0,12,124:4:0 0,15,178:5:0 +X 2882 . G <*> 0 . DP=19;I16=8,11,0,0,700,26464,0,0,1140,68400,0,0,353,8191,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,118:4:0 0,15,176:5:0 +X 2883 . G <*> 0 . DP=19;I16=8,11,0,0,707,26939,0,0,1140,68400,0,0,357,8319,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,121:4:0 0,15,175:5:0 +X 2884 . A <*> 0 . DP=19;I16=7,11,0,0,649,24531,0,0,1080,64800,0,0,335,7787,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,229:9:0 0,12,121:4:0 0,15,181:5:0 +X 2885 . G <*> 0 . DP=19;I16=8,11,0,0,737,29253,0,0,1140,68400,0,0,362,8470,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,113:4:0 0,15,182:5:0 +X 2886 . G A,<*> 0 . DP=18;I16=7,9,1,0,571,21281,20,400,960,57600,60,3600,334,7882,6,36;QS=2.76471,0.235294,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,27,236,27,236,236:9:0 11,0,51,17,54,66:3:1 0,15,171,15,171,171:5:0 +X 2887 . T <*> 0 . DP=19;I16=9,9,0,0,581,20407,0,0,1080,64800,0,0,341,7905,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,213:10:0 0,9,94:3:0 0,15,166:5:0 +X 2888 . C <*> 0 . DP=20;I16=10,10,0,0,714,26630,0,0,1200,72000,0,0,368,8532,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,94:4:0 0,15,159:5:0 +X 2889 . T <*> 0 . DP=19;I16=9,10,0,0,712,27106,0,0,1140,68400,0,0,372,8550,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,114:4:0 0,15,175:5:0 +X 2890 . C <*> 0 . DP=19;I16=9,10,0,0,613,20711,0,0,1140,68400,0,0,376,8584,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,12,95:4:0 0,15,139:5:0 +X 2891 . G <*> 0 . DP=20;I16=9,11,0,0,674,23754,0,0,1200,72000,0,0,380,8634,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,242:10:0 0,15,141:5:0 0,15,143:5:0 +X 2892 . G <*> 0 . DP=21;I16=9,12,0,0,731,26677,0,0,1260,75600,0,0,385,8701,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,142:5:0 0,15,164:5:0 +X 2893 . G <*> 0 . DP=21;I16=9,12,0,0,696,24498,0,0,1260,75600,0,0,389,8687,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,251:11:0 0,15,141:5:0 0,15,150:5:0 +X 2894 . T <*> 0 . DP=21;I16=9,12,0,0,716,25490,0,0,1260,75600,0,0,393,8693,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,137:5:0 0,15,155:5:0 +X 2895 . G <*> 0 . DP=22;I16=9,12,0,0,773,29225,0,0,1260,75600,0,0,372,8094,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,149:6:0 0,15,166:5:0 +X 2896 . A <*> 0 . DP=22;I16=8,12,0,0,732,27684,0,0,1200,72000,0,0,361,7885,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,151:5:0 0,15,163:5:0 +X 2897 . G <*> 0 . DP=22;I16=10,12,0,0,783,28783,0,0,1320,79200,0,0,407,8835,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,161:6:0 0,15,168:5:0 +X 2898 . G <*> 0 . DP=22;I16=10,12,0,0,724,25596,0,0,1320,79200,0,0,412,8926,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,18,143:6:0 0,15,169:5:0 +X 2899 . C <*> 0 . DP=22;I16=8,11,0,0,625,21143,0,0,1140,68400,0,0,356,7640,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,15,130:5:0 0,15,147:5:0 +X 2900 . G <*> 0 . DP=24;I16=11,13,0,0,782,26700,0,0,1440,86400,0,0,420,9078,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,164:6:0 0,15,153:5:0 +X 2901 . T <*> 0 . DP=24;I16=11,13,0,0,821,29195,0,0,1440,86400,0,0,426,9192,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,174:6:0 0,15,166:5:0 +X 2902 . G <*> 0 . DP=24;I16=11,13,0,0,898,34176,0,0,1440,86400,0,0,432,9334,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,171:6:0 0,15,164:5:0 +X 2903 . G <*> 0 . DP=24;I16=11,13,0,0,894,33764,0,0,1440,86400,0,0,437,9455,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,183:6:0 0,15,168:5:0 +X 2904 . C <*> 0 . DP=24;I16=11,13,0,0,892,34010,0,0,1440,86400,0,0,440,9506,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,176:6:0 0,15,169:5:0 +X 2905 . T <*> 0 . DP=25;I16=12,13,0,0,926,34994,0,0,1500,90000,0,0,442,9536,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,175:6:0 0,15,174:5:0 +X 2906 . C <*> 0 . DP=25;I16=12,13,0,0,960,37070,0,0,1500,90000,0,0,444,9544,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,178:6:0 0,15,173:5:0 +X 2907 . A <*> 0 . DP=25;I16=11,13,0,0,933,36707,0,0,1440,86400,0,0,429,9275,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,202:6:0 0,15,170:5:0 +X 2908 . G <*> 0 . DP=25;I16=12,13,0,0,943,36315,0,0,1500,90000,0,0,446,9548,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,167:6:0 0,15,164:5:0 +X 2909 . A <*> 0 . DP=25;I16=10,13,0,0,864,32764,0,0,1380,82800,0,0,425,9105,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,182:6:0 0,15,171:5:0 +X 2910 . T <*> 0 . DP=25;I16=11,13,0,0,870,32054,0,0,1440,86400,0,0,447,9575,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,181:6:0 0,15,166:5:0 +X 2911 . A <*> 0 . DP=25;I16=11,14,0,0,871,31227,0,0,1500,90000,0,0,473,10259,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,174:6:0 0,18,188:6:0 +X 2912 . C <*> 0 . DP=24;I16=11,13,0,0,899,34121,0,0,1440,86400,0,0,474,10298,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,173:6:0 0,18,189:6:0 +X 2913 . A <*> 0 . DP=24;I16=10,13,0,0,879,34357,0,0,1380,82800,0,0,449,9691,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,164:5:0 0,18,199:6:0 +X 2914 . G <*> 0 . DP=24;I16=11,13,0,0,899,34575,0,0,1440,86400,0,0,472,10262,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,170:6:0 0,18,187:6:0 +X 2915 . G <*> 0 . DP=24;I16=11,13,0,0,867,32523,0,0,1440,86400,0,0,470,10236,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,177:6:0 0,18,178:6:0 +X 2916 . G <*> 0 . DP=24;I16=11,12,0,0,813,29935,0,0,1380,82800,0,0,443,9613,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,173:6:0 0,15,155:5:0 +X 2917 . A <*> 0 . DP=25;I16=11,13,0,0,864,31926,0,0,1440,86400,0,0,459,10181,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,185:6:0 0,18,178:6:0 +X 2918 . G <*> 0 . DP=25;I16=13,12,0,0,903,33489,0,0,1500,90000,0,0,462,10122,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,165:6:0 0,18,170:6:0 +X 2919 . T <*> 0 . DP=25;I16=12,12,0,0,837,29647,0,0,1440,86400,0,0,443,9765,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,169:6:0 0,18,178:6:0 +X 2920 . G <*> 0 . DP=25;I16=12,12,0,0,850,31266,0,0,1440,86400,0,0,433,9389,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,132:5:0 0,18,180:6:0 +X 2921 . G <*> 0 . DP=25;I16=13,12,0,0,874,31518,0,0,1500,90000,0,0,455,9951,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,159:6:0 0,18,176:6:0 +X 2922 . C <*> 0 . DP=26;I16=13,12,0,0,872,31374,0,0,1500,90000,0,0,438,9718,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,160:6:0 0,18,172:6:0 +X 2923 . C <*> 0 . DP=26;I16=13,12,0,0,873,31687,0,0,1500,90000,0,0,437,9735,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,172:6:0 0,18,175:6:0 +X 2924 . C <*> 0 . DP=25;I16=13,12,0,0,940,36016,0,0,1500,90000,0,0,449,9921,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,173:6:0 0,18,184:6:0 +X 2925 . A <*> 0 . DP=25;I16=13,12,0,0,912,33580,0,0,1500,90000,0,0,448,9964,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,174:6:0 0,18,189:6:0 +X 2926 . C <*> 0 . DP=25;I16=13,12,0,0,902,33224,0,0,1500,90000,0,0,445,9931,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,176:6:0 0,18,174:6:0 +X 2927 . A <*> 0 . DP=25;I16=12,12,0,0,896,33828,0,0,1440,86400,0,0,417,9295,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,162:5:0 0,18,191:6:0 +X 2928 . G <*> 0 . DP=24;I16=13,11,0,0,862,32078,0,0,1440,86400,0,0,440,9930,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,170:6:0 0,18,161:6:0 +X 2929 . C <*> 0 . DP=23;I16=13,9,0,0,794,29716,0,0,1320,79200,0,0,430,9878,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,153:5:0 0,15,149:5:0 +X 2930 . T <*> 0 . DP=23;I16=13,10,0,0,822,30260,0,0,1380,82800,0,0,438,10006,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,168:6:0 0,15,157:5:0 +X 2931 . C <*> 0 . DP=23;I16=13,10,0,0,803,28963,0,0,1380,82800,0,0,436,10020,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,162:6:0 0,15,140:5:0 +X 2932 . G <*> 0 . DP=22;I16=12,10,0,0,728,25158,0,0,1320,79200,0,0,435,10049,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,171:6:0 0,12,117:4:0 +X 2933 . G <*> 0 . DP=22;I16=11,10,0,0,760,28336,0,0,1260,75600,0,0,430,10034,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,175:6:0 0,12,116:4:0 +X 2934 . C <*> 0 . DP=21;I16=12,9,0,0,759,28241,0,0,1260,75600,0,0,432,10052,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,161:6:0 0,9,104:3:0 +X 2935 . C <*> 0 . DP=21;I16=12,9,0,0,766,28494,0,0,1260,75600,0,0,431,10075,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,178:6:0 0,9,94:3:0 +X 2936 . T <*> 0 . DP=21;I16=11,9,0,0,760,29284,0,0,1200,72000,0,0,429,10063,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,188:6:0 0,9,98:3:0 +X 2937 . G <*> 0 . DP=20;I16=11,9,0,0,728,27374,0,0,1200,72000,0,0,428,10066,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,177:6:0 0,9,79:3:0 +X 2938 . T <*> 0 . DP=20;I16=11,9,0,0,719,26217,0,0,1200,72000,0,0,427,10083,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,188:6:0 0,9,101:3:0 +X 2939 . C <*> 0 . DP=19;I16=11,8,0,0,729,28277,0,0,1140,68400,0,0,427,10113,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,163:5:0 0,9,106:3:0 +X 2940 . T <*> 0 . DP=19;I16=11,8,0,0,739,29133,0,0,1140,68400,0,0,427,10155,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,171:5:0 0,9,109:3:0 +X 2941 . T <*> 0 . DP=19;I16=11,8,0,0,702,26358,0,0,1140,68400,0,0,427,10209,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,170:5:0 0,9,99:3:0 +X 2942 . T <*> 0 . DP=19;I16=11,8,0,0,695,25671,0,0,1140,68400,0,0,427,10275,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,169:5:0 0,9,100:3:0 +X 2943 . G <*> 0 . DP=18;I16=11,6,0,0,621,23187,0,0,1020,61200,0,0,401,9627,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,15,170:5:0 0,9,86:3:0 +X 2944 . A <*> 0 . DP=18;I16=10,7,0,0,642,24406,0,0,1020,61200,0,0,399,9563,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,15,168:5:0 0,9,111:3:0 +X 2945 . A <*> 0 . DP=18;I16=11,7,0,0,637,23199,0,0,1080,64800,0,0,422,10132,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,242:10:0 0,15,152:5:0 0,9,107:3:0 +X 2946 . A <*> 0 . DP=18;I16=11,7,0,0,692,26794,0,0,1080,64800,0,0,420,10084,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,174:5:0 0,9,108:3:0 +X 2947 . G <*> 0 . DP=18;I16=11,7,0,0,639,23329,0,0,1080,64800,0,0,418,10044,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,160:5:0 0,9,78:3:0 +X 2948 . G <*> 0 . DP=19;I16=11,8,0,0,702,26272,0,0,1140,68400,0,0,415,9961,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,163:5:0 0,12,116:4:0 +X 2949 . C <*> 0 . DP=19;I16=10,8,0,0,657,24565,0,0,1080,64800,0,0,388,9260,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,125:4:0 0,12,124:4:0 +X 2950 . C <*> 0 . DP=19;I16=11,8,0,0,667,24359,0,0,1140,68400,0,0,411,9817,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,131:5:0 0,12,115:4:0 +X 2951 . A <*> 0 . DP=20;I16=11,8,0,0,682,24956,0,0,1140,68400,0,0,409,9757,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,15,149:5:0 0,12,133:4:0 +X 2952 . C <*> 0 . DP=20;I16=11,9,0,0,647,21709,0,0,1200,72000,0,0,408,9706,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,128:5:0 0,12,112:4:0 +X 2953 . G <*> 0 . DP=21;I16=11,9,0,0,620,19954,0,0,1200,72000,0,0,407,9665,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,237:11:0 0,15,132:5:0 0,12,111:4:0 +X 2954 . T <*> 0 . DP=21;I16=11,10,0,0,742,26662,0,0,1260,75600,0,0,414,9666,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,175:6:0 0,12,135:4:0 +X 2955 . G <*> 0 . DP=22;I16=11,11,0,0,787,28475,0,0,1320,79200,0,0,412,9568,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,170:6:0 0,12,127:4:0 +X 2956 . A <*> 0 . DP=22;I16=11,11,0,0,747,26449,0,0,1320,79200,0,0,410,9438,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,161:6:0 0,12,125:4:0 +X 2957 . C <*> 0 . DP=22;I16=10,10,0,0,693,24757,0,0,1200,72000,0,0,358,8078,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,143:6:0 0,9,104:3:0 +X 2958 . C <*> 0 . DP=21;I16=11,10,0,0,784,29744,0,0,1260,75600,0,0,407,9237,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,172:6:0 0,12,135:4:0 +X 2959 . T <*> 0 . DP=21;I16=11,10,0,0,791,30411,0,0,1260,75600,0,0,406,9164,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,182:6:0 0,12,139:4:0 +X 2960 . G <*> 0 . DP=21;I16=11,10,0,0,778,29502,0,0,1260,75600,0,0,405,9109,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,178:6:0 0,12,126:4:0 +X 2961 . G <*> 0 . DP=20;I16=10,9,0,0,657,23303,0,0,1140,68400,0,0,380,8446,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,231:10:0 0,18,176:6:0 0,9,111:3:0 +X 2962 . C <*> 0 . DP=21;I16=10,10,0,0,731,27459,0,0,1200,72000,0,0,385,8615,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,151:5:0 0,12,132:4:0 +X 2963 . C <*> 0 . DP=21;I16=10,10,0,0,722,26502,0,0,1200,72000,0,0,378,8274,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,169:6:0 0,9,100:3:0 +X 2964 . C <*> 0 . DP=22;I16=11,10,0,0,752,27740,0,0,1260,75600,0,0,379,8275,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,148:5:0 0,15,151:5:0 +X 2965 . A <*> 0 . DP=22;I16=11,11,0,0,804,29606,0,0,1320,79200,0,0,397,8539,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,176:6:0 0,15,155:5:0 +X 2966 . C <*> 0 . DP=22;I16=11,11,0,0,705,23557,0,0,1320,79200,0,0,396,8468,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,18,146:6:0 0,15,142:5:0 +X 2967 . G <*> 0 . DP=24;I16=11,13,0,0,767,25405,0,0,1440,86400,0,0,393,8325,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,162:6:0 0,18,135:6:0 +X 2968 . G <*> 0 . DP=23;I16=11,12,0,0,812,29824,0,0,1380,82800,0,0,393,8213,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,152:5:0 0,18,162:6:0 +X 2969 . C <*> 0 . DP=23;I16=11,12,0,0,866,32982,0,0,1380,82800,0,0,393,8133,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,151:5:0 0,18,181:6:0 +X 2970 . T <*> 0 . DP=24;I16=11,12,0,0,816,29806,0,0,1380,82800,0,0,393,8085,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,154:5:0 0,18,189:6:0 +X 2971 . G <*> 0 . DP=24;I16=12,12,0,0,878,33010,0,0,1440,86400,0,0,392,7970,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,173:6:0 0,18,184:6:0 +X 2972 . G <*> 0 . DP=24;I16=12,12,0,0,839,30363,0,0,1440,86400,0,0,391,7889,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,175:6:0 0,18,161:6:0 +X 2973 . C <*> 0 . DP=24;I16=12,12,0,0,854,31154,0,0,1440,86400,0,0,390,7842,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,177:6:0 0,18,165:6:0 +X 2974 . A <*> 0 . DP=24;I16=12,12,0,0,869,32231,0,0,1440,86400,0,0,388,7778,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,169:6:0 0,18,174:6:0 +X 2975 . G <*> 0 . DP=24;I16=12,12,0,0,857,31835,0,0,1440,86400,0,0,384,7648,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,173:6:0 0,18,167:6:0 +X 2976 . G <*> 0 . DP=25;I16=13,12,0,0,866,31118,0,0,1500,90000,0,0,380,7554,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,180:7:0 0,18,171:6:0 +X 2977 . T <*> 0 . DP=26;I16=13,12,0,0,760,25216,0,0,1469,87241,0,0,373,7437,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,151:6:0 0,18,155:6:0 +X 2978 . G <*> 0 . DP=25;I16=12,12,0,0,862,31574,0,0,1409,83641,0,0,362,7290,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,168:6:0 0,18,167:6:0 +X 2979 . G <*> 0 . DP=24;I16=12,12,0,0,816,28440,0,0,1409,83641,0,0,370,7340,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,164:6:0 0,15,142:5:0 +X 2980 . G <*> 0 . DP=23;I16=12,11,0,0,834,30882,0,0,1349,80041,0,0,369,7293,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,144:5:0 0,15,148:5:0 +X 2981 . A <*> 0 . DP=23;I16=9,11,0,0,622,20306,0,0,1169,69241,0,0,318,6244,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,30,201:10:0 0,15,145:5:0 0,15,150:5:0 +X 2982 . C <*> 0 . DP=23;I16=10,11,0,0,706,24366,0,0,1229,72841,0,0,340,6884,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,93:3:0 0,15,144:5:0 +X 2983 . C <*> 0 . DP=23;I16=12,11,0,0,781,27427,0,0,1349,80041,0,0,363,7197,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,137:5:0 0,15,142:5:0 +X 2984 . C <*> 0 . DP=23;I16=12,11,0,0,861,32655,0,0,1349,80041,0,0,361,7229,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,154:5:0 0,15,157:5:0 +X 2985 . A <*> 0 . DP=23;I16=12,11,0,0,798,28906,0,0,1349,80041,0,0,359,7293,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,161:5:0 0,15,151:5:0 +X 2986 . G <*> 0 . DP=21;I16=11,10,0,0,701,24335,0,0,1229,72841,0,0,358,7388,0,0;QS=3,0;MQSB=0.939898;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,129:5:0 0,12,126:4:0 +X 2987 . C <*> 0 . DP=21;I16=10,10,0,0,720,26782,0,0,1169,69241,0,0,350,7448,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,136:4:0 0,12,132:4:0 +X 2988 . T <*> 0 . DP=20;I16=10,10,0,0,693,25143,0,0,1169,69241,0,0,358,7612,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,132:5:0 0,12,136:4:0 +X 2989 . G <*> 0 . DP=20;I16=10,10,0,0,708,25886,0,0,1169,69241,0,0,358,7736,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,141:5:0 0,12,125:4:0 +X 2990 . C <*> 0 . DP=20;I16=10,10,0,0,697,25083,0,0,1169,69241,0,0,357,7833,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,149:5:0 0,12,129:4:0 +X 2991 . A <*> 0 . DP=20;I16=10,10,0,0,717,26309,0,0,1169,69241,0,0,356,7952,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,151:5:0 0,12,131:4:0 +X 2992 . G <*> 0 . DP=18;I16=10,8,0,0,625,22505,0,0,1049,62041,0,0,356,8042,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,12,130:4:0 0,12,120:4:0 +X 2993 . G <*> 0 . DP=18;I16=10,8,0,0,646,23620,0,0,1049,62041,0,0,354,8050,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,118:4:0 0,12,123:4:0 +X 2994 . G <*> 0 . DP=18;I16=10,8,0,0,620,21828,0,0,1049,62041,0,0,351,8025,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,30,254:10:0 0,12,115:4:0 0,12,116:4:0 +X 2995 . G <*> 0 . DP=18;I16=10,8,0,0,628,22284,0,0,1049,62041,0,0,348,8018,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,12,110:4:0 0,12,135:4:0 +X 2996 . T <*> 0 . DP=17;I16=8,8,0,0,497,16697,0,0,929,54841,0,0,323,7493,0,0;QS=3,0;MQSB=0.915545;MQ0F=0 PL:DP:DV 0,30,215:10:0 0,9,75:3:0 0,9,107:3:0 +X 2997 . C <*> 0 . DP=17;I16=9,8,0,0,603,21925,0,0,989,58441,0,0,341,7901,0,0;QS=3,0;MQSB=0.928603;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,85:3:0 0,12,115:4:0 +X 2998 . C <*> 0 . DP=17;I16=9,8,0,0,576,19964,0,0,989,58441,0,0,337,7841,0,0;QS=3,0;MQSB=0.928603;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,9,84:3:0 0,12,123:4:0 +X 2999 . A <*> 0 . DP=17;I16=9,8,0,0,599,22077,0,0,989,58441,0,0,333,7797,0,0;QS=3,0;MQSB=0.928603;MQ0F=0 PL:DP:DV 0,30,238:10:0 0,9,109:3:0 0,12,136:4:0 +X 3000 . G <*> 0 . DP=15;I16=8,7,0,0,554,20620,0,0,869,51241,0,0,331,7767,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,24,220:8:0 0,9,102:3:0 0,12,135:4:0 +X 3001 . C <*> 0 . DP=15;I16=7,7,0,0,521,19695,0,0,809,47641,0,0,309,7349,0,0;QS=3,0;MQSB=0.885987;MQ0F=0 PL:DP:DV 0,21,213:7:0 0,9,103:3:0 0,12,128:4:0 +X 3002 . A <*> 0 . DP=15;I16=8,7,0,0,542,20082,0,0,869,51241,0,0,326,7692,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,24,224:8:0 0,9,92:3:0 0,12,139:4:0 +X 3003 . G <*> 0 . DP=15;I16=8,7,0,0,540,19814,0,0,869,51241,0,0,322,7594,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,24,230:8:0 0,9,96:3:0 0,12,120:4:0 +X 3004 . C <*> 0 . DP=15;I16=8,7,0,0,525,19113,0,0,869,51241,0,0,318,7504,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,24,211:8:0 0,9,100:3:0 0,12,129:4:0 +X 3005 . A <*> 0 . DP=14;I16=7,7,0,0,491,17343,0,0,809,47641,0,0,315,7421,0,0;QS=3,0;MQSB=0.885987;MQ0F=0 PL:DP:DV 0,21,197:7:0 0,9,95:3:0 0,12,124:4:0 +X 3006 . C <*> 0 . DP=16;I16=7,8,0,0,516,18376,0,0,869,51241,0,0,312,7344,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,24,200:8:0 0,9,95:3:0 0,12,135:4:0 +X 3007 . C <*> 0 . DP=16;I16=7,8,0,0,553,20853,0,0,869,51241,0,0,310,7274,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,24,214:8:0 0,9,103:3:0 0,12,144:4:0 +X 3008 . C <*> 0 . DP=16;I16=7,8,0,0,576,22238,0,0,869,51241,0,0,308,7212,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,24,228:8:0 0,9,105:3:0 0,12,145:4:0 +X 3009 . A <*> 0 . DP=16;I16=7,8,0,0,493,16739,0,0,869,51241,0,0,306,7158,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,24,200:8:0 0,9,83:3:0 0,12,130:4:0 +X 3010 . C <*> 0 . DP=15;I16=7,7,0,0,534,20464,0,0,809,47641,0,0,300,7096,0,0;QS=3,0;MQSB=0.885987;MQ0F=0 PL:DP:DV 0,21,211:7:0 0,9,106:3:0 0,12,135:4:0 +X 3011 . A <*> 0 . DP=16;I16=7,8,0,0,559,21173,0,0,869,51241,0,0,302,7074,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,24,218:8:0 0,9,104:3:0 0,12,145:4:0 +X 3012 . G <*> 0 . DP=16;I16=7,8,0,0,503,17903,0,0,869,51241,0,0,300,7044,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,24,193:8:0 0,9,93:3:0 0,12,141:4:0 +X 3013 . C <*> 0 . DP=16;I16=7,9,0,0,549,19967,0,0,898,52082,0,0,305,7071,0,0;QS=3,0;MQSB=0.994413;MQ0F=0 PL:DP:DV 0,27,207:9:0 0,9,98:3:0 0,12,141:4:0 +X 3014 . A <*> 0 . DP=18;I16=6,9,0,0,542,20362,0,0,838,48482,0,0,289,6959,0,0;QS=3,0;MQSB=0.984496;MQ0F=0 PL:DP:DV 0,24,195:8:0 0,9,109:3:0 0,12,141:4:0 +X 3015 . G <*> 0 . DP=20;I16=7,9,0,0,549,19441,0,0,929,54841,0,0,311,7547,0,0;QS=3,0;MQSB=0.892753;MQ0F=0 PL:DP:DV 0,24,206:8:0 0,12,116:4:0 0,12,131:4:0 +X 3016 . C <*> 0 . DP=20;I16=7,13,0,0,690,24374,0,0,1138,66482,0,0,337,7783,0,0;QS=3,0;MQSB=0.972138;MQ0F=0 PL:DP:DV 0,33,248:11:0 0,15,136:5:0 0,12,132:4:0 +X 3017 . C A,<*> 0 . DP=20;I16=7,12,0,1,650,23264,23,529,1109,65641,29,841,329,7715,11,121;QS=2.93801,0.0619946,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.972138;BQB=1;MQ0F=0 PL:DP:DV 0,10,224,30,227,236:11:1 0,15,133,15,133,133:5:0 0,12,128,12,128,128:4:0 +X 3018 . A <*> 0 . DP=21;I16=6,10,0,0,475,15057,0,0,929,54841,0,0,295,6991,0,0;QS=3,0;MQSB=0.863243;MQ0F=0 PL:DP:DV 0,27,192:9:0 0,12,111:4:0 0,9,81:3:0 +X 3019 . C <*> 0 . DP=20;I16=6,12,0,0,618,21842,0,0,1049,62041,0,0,336,7818,0,0;QS=3,0;MQSB=0.85394;MQ0F=0 PL:DP:DV 0,30,242:10:0 0,15,129:5:0 0,9,104:3:0 +X 3020 . C <*> 0 . DP=20;I16=6,12,0,0,588,21046,0,0,1049,62041,0,0,340,7888,0,0;QS=3,0;MQSB=0.85394;MQ0F=0 PL:DP:DV 0,30,221:10:0 0,15,129:5:0 0,9,114:3:0 +X 3021 . T <*> 0 . DP=21;I16=5,13,0,0,618,22454,0,0,1049,62041,0,0,343,7921,0,0;QS=3,0;MQSB=0.814433;MQ0F=0 PL:DP:DV 0,30,216:10:0 0,15,147:5:0 0,9,109:3:0 +X 3022 . G <*> 0 . DP=20;I16=5,13,0,0,672,25292,0,0,1049,62041,0,0,348,7968,0,0;QS=3,0;MQSB=0.814433;MQ0F=0 PL:DP:DV 0,30,234:10:0 0,15,153:5:0 0,9,109:3:0 +X 3023 . T G,<*> 0 . DP=20;I16=5,12,0,1,554,19110,18,324,989,58441,60,3600,336,7740,17,289;QS=2.94231,0.0576923,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.814433;BQB=1;MQ0F=0 PL:DP:DV 0,12,191,27,194,199:10:1 0,15,125,15,125,125:5:0 0,9,111,9,111,111:3:0 +X 3024 . G <*> 0 . DP=20;I16=5,14,0,0,684,25122,0,0,1109,65641,0,0,382,8680,0,0;QS=3,0;MQSB=0.810584;MQ0F=0 PL:DP:DV 0,30,235:10:0 0,18,152:6:0 0,9,113:3:0 +X 3025 . G <*> 0 . DP=20;I16=5,14,0,0,625,21465,0,0,1109,65641,0,0,386,8722,0,0;QS=3,0;MQSB=0.810584;MQ0F=0 PL:DP:DV 0,30,225:10:0 0,18,133:6:0 0,9,109:3:0 +X 3026 . C <*> 0 . DP=20;I16=5,13,0,0,632,23132,0,0,1018,59282,0,0,367,8217,0,0;QS=3,0;MQSB=0.925212;MQ0F=0 PL:DP:DV 0,33,235:11:0 0,12,105:4:0 0,9,107:3:0 +X 3027 . A <*> 0 . DP=21;I16=6,15,0,0,693,24199,0,0,1198,70082,0,0,413,9199,0,0;QS=3,0;MQSB=0.940481;MQ0F=0 PL:DP:DV 0,33,222:11:0 0,21,175:7:0 0,9,108:3:0 +X 3028 . G <*> 0 . DP=21;I16=6,15,0,0,753,27935,0,0,1198,70082,0,0,417,9239,0,0;QS=3,0;MQSB=0.940481;MQ0F=0 PL:DP:DV 0,33,241:11:0 0,21,192:7:0 0,9,107:3:0 +X 3029 . G <*> 0 . DP=21;I16=6,15,0,0,787,29949,0,0,1198,70082,0,0,421,9303,0,0;QS=3,0;MQSB=0.940481;MQ0F=0 PL:DP:DV 0,33,251:11:0 0,21,189:7:0 0,9,109:3:0 +X 3030 . G <*> 0 . DP=22;I16=6,16,0,0,720,24728,0,0,1258,73682,0,0,424,9342,0,0;QS=3,0;MQSB=0.934321;MQ0F=0 PL:DP:DV 0,36,229:12:0 0,21,174:7:0 0,9,106:3:0 +X 3031 . A <*> 0 . DP=22;I16=5,16,0,0,693,24631,0,0,1198,70082,0,0,403,8783,0,0;QS=3,0;MQSB=0.902014;MQ0F=0 PL:DP:DV 0,36,222:12:0 0,18,162:6:0 0,9,113:3:0 +X 3032 . G <*> 0 . DP=22;I16=6,15,0,0,727,26093,0,0,1229,72841,0,0,405,8775,0,0;QS=3,0;MQSB=0.843281;MQ0F=0 PL:DP:DV 0,33,237:11:0 0,21,180:7:0 0,9,106:3:0 +X 3033 . G <*> 0 . DP=22;I16=6,15,0,0,697,24039,0,0,1198,70082,0,0,429,9407,0,0;QS=3,0;MQSB=0.940481;MQ0F=0 PL:DP:DV 0,33,235:11:0 0,21,160:7:0 0,9,106:3:0 +X 3034 . A <*> 0 . DP=23;I16=6,14,0,0,617,20947,0,0,1138,66482,0,0,387,8491,0,0;QS=3,0;MQSB=0.947033;MQ0F=0 PL:DP:DV 0,33,203:11:0 0,15,134:5:0 0,12,126:4:0 +X 3035 . G <*> 0 . DP=23;I16=7,13,0,0,641,22007,0,0,1138,66482,0,0,385,8379,0,0;QS=3,0;MQSB=0.972138;MQ0F=0 PL:DP:DV 0,30,208:10:0 0,18,151:6:0 0,12,128:4:0 +X 3036 . C <*> 0 . DP=23;I16=6,15,0,0,688,23652,0,0,1198,70082,0,0,388,8258,0,0;QS=3,0;MQSB=0.940481;MQ0F=0 PL:DP:DV 0,36,216:12:0 0,15,132:5:0 0,12,140:4:0 +X 3037 . T <*> 0 . DP=24;I16=7,16,0,0,797,28671,0,0,1318,77282,0,0,439,9521,0,0;QS=3,0;MQSB=0.955805;MQ0F=0 PL:DP:DV 0,36,242:12:0 0,21,170:7:0 0,12,143:4:0 +X 3038 . T <*> 0 . DP=25;I16=8,17,0,0,815,27469,0,0,1438,84482,0,0,441,9561,0,0;QS=3,0;MQSB=0.966223;MQ0F=0 PL:DP:DV 0,42,249:14:0 0,21,190:7:0 0,12,125:4:0 +X 3039 . G <*> 0 . DP=25;I16=8,17,0,0,780,25946,0,0,1438,84482,0,0,444,9630,0,0;QS=3,0;MQSB=0.966223;MQ0F=0 PL:DP:DV 0,42,249:14:0 0,21,156:7:0 0,12,127:4:0 +X 3040 . T <*> 0 . DP=25;I16=7,15,0,0,701,23777,0,0,1258,73682,0,0,385,8279,0,0;QS=3,0;MQSB=0.961028;MQ0F=0 PL:DP:DV 0,36,239:12:0 0,18,154:6:0 0,12,130:4:0 +X 3041 . G <*> 0 . DP=25;I16=8,16,0,0,824,29228,0,0,1378,80882,0,0,420,8982,0,0;QS=3,0;MQSB=0.970446;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,186:7:0 0,12,135:4:0 +X 3042 . G <*> 0 . DP=25;I16=8,15,0,0,795,28227,0,0,1349,80041,0,0,409,8839,0,0;QS=3,0;MQSB=0.889418;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,148:6:0 0,12,120:4:0 +X 3043 . T <*> 0 . DP=25;I16=8,16,0,0,723,23191,0,0,1378,80882,0,0,435,9415,0,0;QS=3,0;MQSB=0.970446;MQ0F=0 PL:DP:DV 0,39,233:13:0 0,21,151:7:0 0,12,124:4:0 +X 3044 . A C,<*> 0 . DP=26;I16=8,15,0,1,665,20809,15,225,1318,77282,60,3600,392,8498,14,196;QS=2.96104,0.038961,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.970446;BQB=1;MQ0F=0 PL:DP:DV 0,26,216,39,219,220:14:1 0,18,133,18,133,133:6:0 0,12,124,12,124,124:4:0 +X 3045 . C <*> 0 . DP=26;I16=8,16,0,0,754,25232,0,0,1378,80882,0,0,403,8627,0,0;QS=3,0;MQSB=0.970446;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,133:6:0 0,12,122:4:0 +X 3046 . A <*> 0 . DP=25;I16=8,15,0,0,748,26170,0,0,1349,80041,0,0,400,8540,0,0;QS=3,0;MQSB=0.889418;MQ0F=0 PL:DP:DV 0,39,245:13:0 0,18,160:6:0 0,12,141:4:0 +X 3047 . G <*> 0 . DP=25;I16=8,15,0,0,766,26998,0,0,1318,77282,0,0,396,8432,0,0;QS=3,0;MQSB=0.974802;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,143:6:0 0,12,129:4:0 +X 3048 . T <*> 0 . DP=25;I16=8,11,0,0,608,20554,0,0,1109,65641,0,0,320,6762,0,0;QS=3,0;MQSB=0.902014;MQ0F=0 PL:DP:DV 0,30,226:10:0 0,15,128:5:0 0,12,129:4:0 +X 3049 . G <*> 0 . DP=24;I16=8,16,0,0,831,29557,0,0,1378,80882,0,0,426,9068,0,0;QS=3,0;MQSB=0.970446;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,161:6:0 0,9,105:3:0 +X 3050 . G <*> 0 . DP=24;I16=8,14,0,0,729,25093,0,0,1258,73682,0,0,379,8041,0,0;QS=3,0;MQSB=0.979255;MQ0F=0 PL:DP:DV 0,39,253:13:0 0,18,159:6:0 0,9,100:3:0 +X 3051 . A <*> 0 . DP=23;I16=8,15,0,0,724,24200,0,0,1318,77282,0,0,423,9091,0,0;QS=3,0;MQSB=0.974802;MQ0F=0 PL:DP:DV 0,42,243:14:0 0,18,152:6:0 0,9,103:3:0 +X 3052 . C <*> 0 . DP=23;I16=7,13,0,0,612,19876,0,0,1169,69241,0,0,363,7779,0,0;QS=3,0;MQSB=0.962269;MQ0F=0 PL:DP:DV 0,36,226:12:0 0,15,117:5:0 0,9,93:3:0 +X 3053 . A <*> 0 . DP=22;I16=8,11,0,0,616,21288,0,0,1078,62882,0,0,360,7740,0,0;QS=3,0;MQSB=0.992359;MQ0F=0 PL:DP:DV 0,33,234:11:0 0,15,118:5:0 0,9,110:3:0 +X 3054 . G <*> 0 . DP=22;I16=8,14,0,0,761,27617,0,0,1258,73682,0,0,414,8932,0,0;QS=3,0;MQSB=0.979255;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,126:5:0 0,9,99:3:0 +X 3055 . G <*> 0 . DP=22;I16=8,9,0,0,566,19890,0,0,958,55682,0,0,333,7219,0,0;QS=3,0;MQSB=0.998843;MQ0F=0 PL:DP:DV 0,30,228:10:0 0,12,111:4:0 0,9,105:3:0 +X 3056 . C <*> 0 . DP=22;I16=7,14,0,0,701,24685,0,0,1198,70082,0,0,420,9298,0,0;QS=3,0;MQSB=0.966484;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,125:4:0 0,12,122:4:0 +X 3057 . C <*> 0 . DP=23;I16=8,13,0,0,706,24988,0,0,1198,70082,0,0,411,9253,0,0;QS=3,0;MQSB=0.983744;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,128:5:0 0,9,92:3:0 +X 3058 . C <*> 0 . DP=23;I16=9,14,0,0,707,23327,0,0,1318,77282,0,0,429,9471,0,0;QS=3,0;MQSB=0.987676;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,131:5:0 0,12,116:4:0 +X 3059 . T G,<*> 0 . DP=23;I16=9,11,0,1,638,21954,16,256,1169,69241,60,3600,355,7761,22,484;QS=2.95876,0.0412371,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.913101;BQB=1;MQ0F=0 PL:DP:DV 0,22,234,36,237,239:13:1 0,15,144,15,144,144:5:0 0,9,94,9,94,94:3:0 +X 3060 . G <*> 0 . DP=24;I16=9,10,0,0,578,19136,0,0,1109,65641,0,0,324,6992,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,33,221:11:0 0,12,121:4:0 0,12,116:4:0 +X 3061 . C <*> 0 . DP=24;I16=9,15,0,0,770,25918,0,0,1378,80882,0,0,446,10136,0,0;QS=3,0;MQSB=0.984127;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,138:5:0 0,15,145:5:0 +X 3062 . C <*> 0 . DP=23;I16=9,13,0,0,727,25019,0,0,1289,76441,0,0,419,9551,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,137:5:0 0,15,134:5:0 +X 3063 . C <*> 0 . DP=23;I16=9,13,0,0,651,21695,0,0,1258,73682,0,0,415,9511,0,0;QS=3,0;MQSB=0.991121;MQ0F=0 PL:DP:DV 0,36,233:12:0 0,15,130:5:0 0,15,133:5:0 +X 3064 . A <*> 0 . DP=23;I16=9,12,0,0,691,24125,0,0,1198,70082,0,0,385,8815,0,0;QS=3,0;MQSB=0.994334;MQ0F=0 PL:DP:DV 0,36,254:12:0 0,12,118:4:0 0,15,144:5:0 +X 3065 . G <*> 0 . DP=22;I16=7,14,0,0,653,21733,0,0,1198,70082,0,0,426,9986,0,0;QS=3,0;MQSB=0.966484;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,109:4:0 0,12,118:4:0 +X 3066 . A <*> 0 . DP=21;I16=7,10,0,0,501,16143,0,0,989,58441,0,0,326,7598,0,0;QS=3,0;MQSB=0.887766;MQ0F=0 PL:DP:DV 0,27,202:9:0 0,12,109:4:0 0,12,104:4:0 +X 3067 . T <*> 0 . DP=21;I16=7,12,0,0,535,16779,0,0,1078,62882,0,0,373,8787,0,0;QS=3,0;MQSB=0.977926;MQ0F=0 PL:DP:DV 0,36,223:12:0 0,9,82:3:0 0,12,103:4:0 +X 3068 . G <*> 0 . DP=20;I16=7,12,0,0,645,22781,0,0,1109,65641,0,0,396,9312,0,0;QS=3,0;MQSB=0.879351;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,115:4:0 0,9,84:3:0 +X 3069 . G <*> 0 . DP=20;I16=7,10,0,0,468,14412,0,0,989,58441,0,0,346,8070,0,0;QS=3,0;MQSB=0.887766;MQ0F=0 PL:DP:DV 0,33,203:11:0 0,12,102:4:0 0,6,57:2:0 +X 3070 . C <*> 0 . DP=20;I16=6,13,0,0,627,22135,0,0,1078,62882,0,0,414,9878,0,0;QS=3,0;MQSB=0.953977;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,98:3:0 0,9,98:3:0 +X 3071 . C <*> 0 . DP=20;I16=7,13,0,0,715,26563,0,0,1138,66482,0,0,419,9893,0,0;QS=3,0;MQSB=0.972138;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,123:4:0 0,9,98:3:0 +X 3072 . C <*> 0 . DP=20;I16=6,13,0,0,696,25784,0,0,1109,65641,0,0,414,9866,0,0;QS=3,0;MQSB=0.965977;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,128:4:0 0,9,106:3:0 +X 3073 . C <*> 0 . DP=20;I16=6,13,0,0,706,26822,0,0,1109,65641,0,0,414,9872,0,0;QS=3,0;MQSB=0.965977;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,135:4:0 0,9,115:3:0 +X 3074 . C <*> 0 . DP=20;I16=6,13,0,0,724,28052,0,0,1109,65641,0,0,414,9886,0,0;QS=3,0;MQSB=0.965977;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,135:4:0 0,9,116:3:0 +X 3075 . C <*> 0 . DP=21;I16=6,13,0,0,630,21614,0,0,1109,65641,0,0,389,9283,0,0;QS=3,0;MQSB=0.965977;MQ0F=0 PL:DP:DV 0,33,239:11:0 0,15,140:5:0 0,9,94:3:0 +X 3076 . G <*> 0 . DP=21;I16=6,14,0,0,645,21809,0,0,1169,69241,0,0,415,9939,0,0;QS=3,0;MQSB=0.969852;MQ0F=0 PL:DP:DV 0,36,252:12:0 0,15,126:5:0 0,9,91:3:0 +X 3077 . C <*> 0 . DP=20;I16=5,15,0,0,694,25228,0,0,1169,69241,0,0,417,9979,0,0;QS=3,0;MQSB=0.976472;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,116:4:0 0,9,111:3:0 +X 3078 . C <*> 0 . DP=20;I16=5,15,0,0,767,29761,0,0,1169,69241,0,0,420,10028,0,0;QS=3,0;MQSB=0.976472;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,113:4:0 0,9,111:3:0 +X 3079 . T <*> 0 . DP=20;I16=5,15,0,0,749,28479,0,0,1169,69241,0,0,422,10038,0,0;QS=3,0;MQSB=0.976472;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,119:4:0 0,9,116:3:0 +X 3080 . G <*> 0 . DP=21;I16=6,15,0,0,785,29901,0,0,1229,72841,0,0,424,10060,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,124:4:0 0,9,103:3:0 +X 3081 . C <*> 0 . DP=21;I16=6,15,0,0,752,27438,0,0,1229,72841,0,0,425,9997,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,118:4:0 0,9,92:3:0 +X 3082 . C <*> 0 . DP=21;I16=6,15,0,0,787,30211,0,0,1229,72841,0,0,426,9952,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,118:4:0 0,9,112:3:0 +X 3083 . T C,<*> 0 . DP=21;I16=6,14,0,1,764,29458,33,1089,1169,69241,60,3600,401,9249,25,625;QS=2.93666,0.0633397,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.973096;BQB=1;MQ0F=0 PL:DP:DV 0,9,255,39,255,255:14:1 0,12,130,12,130,130:4:0 0,9,113,9,113,113:3:0 +X 3084 . G <*> 0 . DP=23;I16=6,17,0,0,859,32755,0,0,1349,80041,0,0,426,9812,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,118:4:0 0,12,135:4:0 +X 3085 . T <*> 0 . DP=23;I16=6,16,0,0,824,31132,0,0,1289,76441,0,0,426,9718,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,124:4:0 0,12,135:4:0 +X 3086 . G <*> 0 . DP=23;I16=6,17,0,0,853,32429,0,0,1349,80041,0,0,428,9648,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,125:4:0 0,12,131:4:0 +X 3087 . G <*> 0 . DP=23;I16=6,17,0,0,897,35253,0,0,1349,80041,0,0,429,9599,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,130:4:0 0,12,137:4:0 +X 3088 . A <*> 0 . DP=22;I16=6,16,0,0,834,31738,0,0,1289,76441,0,0,431,9571,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,110:3:0 0,12,135:4:0 +X 3089 . A <*> 0 . DP=23;I16=7,16,0,0,919,36903,0,0,1349,80041,0,0,432,9514,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,113:3:0 0,15,175:5:0 +X 3090 . G <*> 0 . DP=23;I16=7,16,0,0,885,34349,0,0,1349,80041,0,0,433,9431,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,103:3:0 0,15,160:5:0 +X 3091 . T <*> 0 . DP=23;I16=7,16,0,0,840,31352,0,0,1349,80041,0,0,434,9374,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,105:3:0 0,15,153:5:0 +X 3092 . T <*> 0 . DP=24;I16=8,16,0,0,895,33673,0,0,1409,83641,0,0,434,9294,0,0;QS=3,0;MQSB=0.970446;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,109:3:0 0,15,165:5:0 +X 3093 . G <*> 0 . DP=25;I16=9,16,0,0,955,37033,0,0,1469,87241,0,0,434,9192,0,0;QS=3,0;MQSB=0.968069;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,133:4:0 0,15,157:5:0 +X 3094 . A <*> 0 . DP=25;I16=9,15,0,0,891,33319,0,0,1409,83641,0,0,425,9019,0,0;QS=3,0;MQSB=0.96464;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,134:4:0 0,15,161:5:0 +X 3095 . C <*> 0 . DP=25;I16=9,15,0,0,891,33469,0,0,1409,83641,0,0,425,8955,0,0;QS=3,0;MQSB=0.96464;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,131:4:0 0,15,163:5:0 +X 3096 . C <*> 0 . DP=25;I16=9,16,0,0,952,36626,0,0,1469,87241,0,0,436,9014,0,0;QS=3,0;MQSB=0.968069;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,121:4:0 0,15,167:5:0 +X 3097 . A <*> 0 . DP=25;I16=9,16,0,0,972,38200,0,0,1469,87241,0,0,436,8984,0,0;QS=3,0;MQSB=0.968069;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,144:4:0 0,15,174:5:0 +X 3098 . G <*> 0 . DP=25;I16=9,16,0,0,959,37269,0,0,1469,87241,0,0,436,8986,0,0;QS=3,0;MQSB=0.968069;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,134:4:0 0,15,166:5:0 +X 3099 . A <*> 0 . DP=25;I16=9,16,0,0,888,32632,0,0,1469,87241,0,0,435,8971,0,0;QS=3,0;MQSB=0.968069;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,124:4:0 0,15,165:5:0 +X 3100 . C <*> 0 . DP=25;I16=9,16,0,0,870,31084,0,0,1469,87241,0,0,434,8990,0,0;QS=3,0;MQSB=0.968069;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,126:4:0 0,15,159:5:0 +X 3101 . C <*> 0 . DP=25;I16=9,16,0,0,960,37090,0,0,1469,87241,0,0,432,8992,0,0;QS=3,0;MQSB=0.968069;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,134:4:0 0,15,161:5:0 +X 3102 . A <*> 0 . DP=26;I16=10,16,0,0,952,35186,0,0,1529,90841,0,0,430,9026,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,134:4:0 0,18,189:6:0 +X 3103 . T <*> 0 . DP=26;I16=10,16,0,0,920,33094,0,0,1529,90841,0,0,427,8993,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,131:4:0 0,18,187:6:0 +X 3104 . C T,<*> 0 . DP=25;I16=8,15,2,0,900,35584,80,3202,1349,80041,120,7200,385,8143,40,850;QS=2.58763,0.412371,0;VDB=0.8;SGB=0.346553;RPB=0.717391;MQB=0.956522;MQSB=0.962269;BQB=0.978261;MQ0F=0 PL:DP:DV 0,48,255,48,255,255:16:0 0,12,144,12,144,144:4:0 59,0,93,68,99,157:5:2 +X 3105 . T <*> 0 . DP=25;I16=10,15,0,0,959,37057,0,0,1469,87241,0,0,422,8976,0,0;QS=3,0;MQSB=0.962269;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,149:4:0 0,15,169:5:0 +X 3106 . G <*> 0 . DP=23;I16=10,13,0,0,881,33891,0,0,1380,82800,0,0,420,8940,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,132:4:0 0,15,167:5:0 +X 3107 . T <*> 0 . DP=24;I16=10,14,0,0,878,32496,0,0,1440,86400,0,0,418,8932,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,132:4:0 0,18,195:6:0 +X 3108 . C <*> 0 . DP=24;I16=10,14,0,0,909,34897,0,0,1440,86400,0,0,417,8953,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,137:4:0 0,18,189:6:0 +X 3109 . A <*> 0 . DP=24;I16=10,14,0,0,905,34249,0,0,1440,86400,0,0,416,9004,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,136:4:0 0,18,195:6:0 +X 3110 . C <*> 0 . DP=24;I16=10,13,0,0,919,37099,0,0,1380,82800,0,0,413,8933,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,105:3:0 0,18,189:6:0 +X 3111 . A <*> 0 . DP=25;I16=10,14,0,0,961,38943,0,0,1440,86400,0,0,410,8888,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,111:3:0 0,18,205:6:0 +X 3112 . G <*> 0 . DP=25;I16=10,14,0,0,958,39370,0,0,1440,86400,0,0,407,8821,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,116:3:0 0,18,191:6:0 +X 3113 . C <*> 0 . DP=25;I16=10,14,0,0,961,39641,0,0,1440,86400,0,0,403,8735,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,112:3:0 0,18,193:6:0 +X 3114 . A <*> 0 . DP=24;I16=10,13,0,0,928,38448,0,0,1380,82800,0,0,400,8680,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,116:3:0 0,18,200:6:0 +X 3115 . G <*> 0 . DP=23;I16=10,12,0,0,872,35800,0,0,1320,79200,0,0,397,8603,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,117:3:0 0,18,195:6:0 +X 3116 . G <*> 0 . DP=23;I16=10,12,0,0,870,35372,0,0,1320,79200,0,0,394,8552,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,108:3:0 0,18,194:6:0 +X 3117 . T <*> 0 . DP=22;I16=9,13,0,0,771,27537,0,0,1320,79200,0,0,399,8575,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,96:3:0 0,18,177:6:0 +X 3118 . A <*> 0 . DP=22;I16=9,13,0,0,813,30285,0,0,1320,79200,0,0,397,8537,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,111:3:0 0,18,193:6:0 +X 3119 . A <*> 0 . DP=22;I16=9,13,0,0,886,35954,0,0,1320,79200,0,0,393,8423,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,120:3:0 0,18,207:6:0 +X 3120 . G <*> 0 . DP=22;I16=9,13,0,0,839,32281,0,0,1320,79200,0,0,389,8333,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,104:3:0 0,18,182:6:0 +X 3121 . A <*> 0 . DP=22;I16=10,12,0,0,777,28399,0,0,1320,79200,0,0,386,8266,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,111:3:0 0,18,194:6:0 +X 3122 . C <*> 0 . DP=22;I16=10,12,0,0,848,33002,0,0,1320,79200,0,0,384,8222,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,110:3:0 0,18,192:6:0 +X 3123 . T <*> 0 . DP=22;I16=10,12,0,0,854,33456,0,0,1320,79200,0,0,382,8202,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,114:3:0 0,18,204:6:0 +X 3124 . C <*> 0 . DP=22;I16=10,11,0,0,882,38286,0,0,1260,75600,0,0,381,8205,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,104:3:0 0,15,178:5:0 +X 3125 . T <*> 0 . DP=22;I16=10,11,0,0,860,36764,0,0,1260,75600,0,0,380,8230,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,106:3:0 0,15,185:5:0 +X 3126 . G <*> 0 . DP=22;I16=10,11,0,0,834,34998,0,0,1260,75600,0,0,379,8277,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,97:3:0 0,15,174:5:0 +X 3127 . C <*> 0 . DP=23;I16=10,11,0,0,847,36381,0,0,1260,75600,0,0,378,8346,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,87:3:0 0,15,175:5:0 +X 3128 . T <*> 0 . DP=22;I16=9,12,0,0,850,35972,0,0,1229,72841,0,0,402,9010,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,107:3:0 0,15,182:5:0 +X 3129 . T <*> 0 . DP=22;I16=9,12,0,0,809,32621,0,0,1229,72841,0,0,401,9067,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,107:3:0 0,15,178:5:0 +X 3130 . T <*> 0 . DP=21;I16=9,10,0,0,744,30322,0,0,1140,68400,0,0,376,8516,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,82:2:0 0,15,169:5:0 +X 3131 . C <*> 0 . DP=21;I16=9,10,0,0,792,34778,0,0,1140,68400,0,0,376,8606,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,83:2:0 0,15,170:5:0 +X 3132 . T <*> 0 . DP=21;I16=9,11,0,0,819,35197,0,0,1169,69241,0,0,400,9288,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,109:3:0 0,15,174:5:0 +X 3133 . G <*> 0 . DP=21;I16=9,11,0,0,800,34016,0,0,1169,69241,0,0,398,9312,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,97:3:0 0,15,166:5:0 +X 3134 . G <*> 0 . DP=22;I16=10,11,0,0,773,30227,0,0,1229,72841,0,0,396,9352,0,0;QS=3,0;MQSB=0.939898;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,97:3:0 0,15,163:5:0 +X 3135 . G <*> 0 . DP=22;I16=9,12,0,0,812,33714,0,0,1229,72841,0,0,396,9408,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,94:3:0 0,12,151:4:0 +X 3136 . C <*> 0 . DP=22;I16=9,12,0,0,811,33469,0,0,1229,72841,0,0,396,9430,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,102:3:0 0,12,140:4:0 +X 3137 . A <*> 0 . DP=22;I16=10,11,0,0,786,31226,0,0,1229,72841,0,0,396,9416,0,0;QS=3,0;MQSB=0.939898;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,95:3:0 0,12,142:4:0 +X 3138 . A <*> 0 . DP=21;I16=9,11,0,0,720,28200,0,0,1169,69241,0,0,398,9414,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,98:3:0 0,12,147:4:0 +X 3139 . C <*> 0 . DP=21;I16=9,11,0,0,755,31433,0,0,1169,69241,0,0,400,9424,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,91:3:0 0,12,139:4:0 +X 3140 . C <*> 0 . DP=21;I16=9,11,0,0,790,33238,0,0,1169,69241,0,0,402,9446,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,102:3:0 0,12,145:4:0 +X 3141 . C <*> 0 . DP=21;I16=9,11,0,0,819,35401,0,0,1169,69241,0,0,404,9480,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,101:3:0 0,12,150:4:0 +X 3142 . A <*> 0 . DP=21;I16=9,11,0,0,822,35744,0,0,1169,69241,0,0,405,9477,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,107:3:0 0,12,155:4:0 +X 3143 . G <*> 0 . DP=22;I16=10,11,0,0,846,36468,0,0,1198,70082,0,0,406,9488,0,0;QS=3,0;MQSB=0.99938;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,104:3:0 0,12,151:4:0 +X 3144 . C <*> 0 . DP=23;I16=12,10,0,0,855,35905,0,0,1258,73682,0,0,409,9513,0,0;QS=3,0;MQSB=0.997828;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,104:3:0 0,15,165:5:0 +X 3145 . A <*> 0 . DP=23;I16=12,10,0,0,869,35937,0,0,1258,73682,0,0,414,9554,0,0;QS=3,0;MQSB=0.997828;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,106:3:0 0,15,174:5:0 +X 3146 . G <*> 0 . DP=23;I16=12,10,0,0,895,38345,0,0,1258,73682,0,0,419,9613,0,0;QS=3,0;MQSB=0.997828;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,105:3:0 0,15,179:5:0 +X 3147 . G <*> 0 . DP=24;I16=11,11,0,0,851,34815,0,0,1289,76441,0,0,419,9623,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,123:4:0 0,15,172:5:0 +X 3148 . T <*> 0 . DP=24;I16=12,11,0,0,795,30097,0,0,1318,77282,0,0,428,9682,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,107:4:0 0,15,149:5:0 +X 3149 . G <*> 0 . DP=24;I16=12,11,0,0,910,38142,0,0,1318,77282,0,0,433,9743,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,120:4:0 0,15,167:5:0 +X 3150 . A <*> 0 . DP=24;I16=12,11,0,0,854,33784,0,0,1318,77282,0,0,438,9822,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,129:4:0 0,15,167:5:0 +X 3151 . C <*> 0 . DP=24;I16=12,11,0,0,873,35315,0,0,1318,77282,0,0,442,9870,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,125:4:0 0,15,163:5:0 +X 3152 . C <*> 0 . DP=24;I16=12,11,0,0,857,34239,0,0,1318,77282,0,0,445,9889,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,123:4:0 0,15,155:5:0 +X 3153 . C <*> 0 . DP=24;I16=12,11,0,0,891,36711,0,0,1318,77282,0,0,448,9930,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,125:4:0 0,15,166:5:0 +X 3154 . T <*> 0 . DP=25;I16=13,11,0,0,938,38052,0,0,1378,80882,0,0,451,9993,0,0;QS=3,0;MQSB=0.998323;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,133:4:0 0,18,194:6:0 +X 3155 . G <*> 0 . DP=25;I16=13,11,0,0,953,39423,0,0,1378,80882,0,0,454,10030,0,0;QS=3,0;MQSB=0.998323;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,127:4:0 0,18,180:6:0 +X 3156 . G <*> 0 . DP=25;I16=13,11,0,0,946,38818,0,0,1378,80882,0,0,457,10093,0,0;QS=3,0;MQSB=0.998323;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,126:4:0 0,18,189:6:0 +X 3157 . A <*> 0 . DP=24;I16=12,12,0,0,896,33648,0,0,1378,80882,0,0,486,10806,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,130:4:0 0,18,193:6:0 +X 3158 . A <*> 0 . DP=24;I16=12,12,0,0,856,31670,0,0,1378,80882,0,0,490,10918,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,125:4:0 0,18,192:6:0 +X 3159 . T <*> 0 . DP=24;I16=11,12,0,0,864,32952,0,0,1349,80041,0,0,477,10749,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,134:4:0 0,18,194:6:0 +X 3160 . T <*> 0 . DP=24;I16=12,12,0,0,907,34719,0,0,1378,80882,0,0,494,11018,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,134:4:0 0,18,193:6:0 +X 3161 . C <*> 0 . DP=24;I16=12,12,0,0,880,33336,0,0,1378,80882,0,0,494,11006,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,123:4:0 0,18,196:6:0 +X 3162 . C <*> 0 . DP=24;I16=12,12,0,0,916,35764,0,0,1378,80882,0,0,494,11018,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,127:4:0 0,18,188:6:0 +X 3163 . T A,<*> 0 . DP=24;I16=11,12,1,0,895,35099,13,169,1349,80041,29,841,473,10603,20,400;QS=2.97436,0.025641,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,28,255,39,255,255:14:1 0,12,137,12,137,137:4:0 0,18,200,18,200,200:6:0 +X 3164 . G <*> 0 . DP=24;I16=12,11,0,0,887,34437,0,0,1349,80041,0,0,467,10385,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,106:3:0 0,18,188:6:0 +X 3165 . T <*> 0 . DP=24;I16=12,12,0,0,880,32654,0,0,1378,80882,0,0,490,10990,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,133:4:0 0,18,189:6:0 +X 3166 . C <*> 0 . DP=24;I16=12,11,0,0,871,33389,0,0,1349,80041,0,0,463,10369,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,111:3:0 0,18,193:6:0 +X 3167 . C <*> 0 . DP=23;I16=12,11,0,0,879,34199,0,0,1318,77282,0,0,487,11021,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,131:4:0 0,18,189:6:0 +X 3168 . A <*> 0 . DP=23;I16=12,11,0,0,874,33294,0,0,1318,77282,0,0,486,11070,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,125:4:0 0,18,192:6:0 +X 3169 . T <*> 0 . DP=23;I16=11,11,0,0,824,31124,0,0,1289,76441,0,0,458,10416,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,128:4:0 0,18,187:6:0 +X 3170 . C <*> 0 . DP=23;I16=11,11,0,0,877,35167,0,0,1289,76441,0,0,453,10307,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,129:4:0 0,18,201:6:0 +X 3171 . T <*> 0 . DP=23;I16=11,11,0,0,843,32615,0,0,1289,76441,0,0,448,10216,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,127:4:0 0,18,201:6:0 +X 3172 . G <*> 0 . DP=23;I16=12,11,0,0,813,29605,0,0,1318,77282,0,0,468,10768,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,120:4:0 0,18,176:6:0 +X 3173 . G <*> 0 . DP=23;I16=11,11,0,0,801,29659,0,0,1289,76441,0,0,436,9988,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,126:4:0 0,18,174:6:0 +X 3174 . C <*> 0 . DP=24;I16=13,11,0,0,938,36926,0,0,1378,80882,0,0,454,10476,0,0;QS=3,0;MQSB=0.998323;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,127:4:0 0,18,194:6:0 +X 3175 . A <*> 0 . DP=25;I16=13,11,0,0,914,35230,0,0,1409,83641,0,0,422,9684,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,127:4:0 0,21,209:7:0 +X 3176 . G <*> 0 . DP=24;I16=14,10,0,0,909,34913,0,0,1378,80882,0,0,442,10164,0,0;QS=3,0;MQSB=0.993166;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,97:3:0 0,21,205:7:0 +X 3177 . G <*> 0 . DP=23;I16=14,9,0,0,793,28159,0,0,1318,77282,0,0,438,10040,0,0;QS=3,0;MQSB=0.987676;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,93:3:0 0,21,195:7:0 +X 3178 . T <*> 0 . DP=23;I16=13,9,0,0,754,26290,0,0,1289,76441,0,0,408,9262,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,96:3:0 0,21,173:7:0 +X 3179 . G <*> 0 . DP=23;I16=13,9,0,0,802,29686,0,0,1289,76441,0,0,403,9131,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,97:3:0 0,21,188:7:0 +X 3180 . G <*> 0 . DP=22;I16=12,9,0,0,701,24107,0,0,1229,72841,0,0,398,8970,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,92:3:0 0,21,175:7:0 +X 3181 . G <*> 0 . DP=22;I16=13,9,0,0,795,29503,0,0,1258,73682,0,0,418,9452,0,0;QS=3,0;MQSB=0.991121;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,99:3:0 0,21,193:7:0 +X 3182 . C <*> 0 . DP=22;I16=12,9,0,0,772,28878,0,0,1198,70082,0,0,396,9038,0,0;QS=3,0;MQSB=0.994334;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,99:3:0 0,21,184:7:0 +X 3183 . A <*> 0 . DP=22;I16=12,9,0,0,766,28304,0,0,1229,72841,0,0,382,8546,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,106:3:0 0,21,193:7:0 +X 3184 . T <*> 0 . DP=21;I16=12,8,0,0,721,26533,0,0,1169,69241,0,0,377,8409,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,9,106:3:0 0,21,196:7:0 +X 3185 . T <*> 0 . DP=20;I16=13,7,0,0,740,27660,0,0,1138,66482,0,0,397,8865,0,0;QS=3,0;MQSB=0.972138;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,103:3:0 0,18,174:6:0 +X 3186 . G <*> 0 . DP=20;I16=13,7,0,0,741,28311,0,0,1138,66482,0,0,391,8665,0,0;QS=3,0;MQSB=0.972138;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,103:3:0 0,18,169:6:0 +X 3187 . A <*> 0 . DP=20;I16=13,7,0,0,693,24927,0,0,1138,66482,0,0,385,8485,0,0;QS=3,0;MQSB=0.972138;MQ0F=0 PL:DP:DV 0,33,247:11:0 0,9,102:3:0 0,18,171:6:0 +X 3188 . A <*> 0 . DP=20;I16=13,7,0,0,704,25746,0,0,1138,66482,0,0,379,8325,0,0;QS=3,0;MQSB=0.972138;MQ0F=0 PL:DP:DV 0,33,249:11:0 0,9,100:3:0 0,18,174:6:0 +X 3189 . A <*> 0 . DP=21;I16=13,8,0,0,763,28171,0,0,1198,70082,0,0,373,8185,0,0;QS=3,0;MQSB=0.983744;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,125:4:0 0,18,174:6:0 +X 3190 . C <*> 0 . DP=20;I16=11,8,0,0,675,24915,0,0,1109,65641,0,0,344,7440,0,0;QS=3,0;MQSB=0.902014;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,123:4:0 0,15,148:5:0 +X 3191 . T <*> 0 . DP=21;I16=11,9,0,0,773,30203,0,0,1169,69241,0,0,340,7340,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,130:4:0 0,15,171:5:0 +X 3192 . G <*> 0 . DP=21;I16=12,9,0,0,751,27785,0,0,1198,70082,0,0,362,7886,0,0;QS=3,0;MQSB=0.994334;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,125:4:0 0,15,152:5:0 +X 3193 . G <*> 0 . DP=21;I16=12,9,0,0,756,27614,0,0,1198,70082,0,0,359,7829,0,0;QS=3,0;MQSB=0.994334;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,121:4:0 0,15,148:5:0 +X 3194 . T C,<*> 0 . DP=21;I16=10,10,1,0,730,26992,18,324,1169,69241,29,841,332,7168,25,625;QS=2.95652,0.0434783,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.99938;BQB=1;MQ0F=0 PL:DP:DV 0,18,255,33,255,255:12:1 0,9,98,9,98,98:3:0 0,18,178,18,178,178:6:0 +X 3195 . T <*> 0 . DP=21;I16=11,10,0,0,776,29184,0,0,1198,70082,0,0,356,7778,0,0;QS=3,0;MQSB=0.99938;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,95:3:0 0,18,189:6:0 +X 3196 . T <*> 0 . DP=21;I16=10,10,0,0,722,26472,0,0,1169,69241,0,0,329,7111,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,91:3:0 0,18,186:6:0 +X 3197 . A <*> 0 . DP=22;I16=12,9,0,0,715,24911,0,0,1229,72841,0,0,352,7718,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,103:3:0 0,18,179:6:0 +X 3198 . A <*> 0 . DP=21;I16=12,8,0,0,745,28155,0,0,1169,69241,0,0,345,7675,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,105:3:0 0,18,198:6:0 +X 3199 . A <*> 0 . DP=21;I16=11,9,0,0,736,27514,0,0,1200,72000,0,0,326,7080,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,105:3:0 0,18,196:6:0 +X 3200 . A <*> 0 . DP=20;I16=11,9,0,0,735,27533,0,0,1169,69241,0,0,350,7660,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,108:3:0 0,18,195:6:0 +X 3201 . A <*> 0 . DP=20;I16=11,8,0,0,706,26814,0,0,1109,65641,0,0,338,7486,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,9,107:3:0 0,18,198:6:0 +X 3202 . T <*> 0 . DP=20;I16=10,9,0,0,692,25620,0,0,1140,68400,0,0,321,6907,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,9,109:3:0 0,18,187:6:0 +X 3203 . G A,<*> 0 . DP=19;I16=9,9,1,0,644,23760,19,361,1080,64800,29,841,320,6872,25,625;QS=2.94823,0.0517711,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.934728;BQB=1;MQ0F=0 PL:DP:DV 0,14,239,30,242,248:11:1 0,9,105,9,105,105:3:0 0,15,160,15,160,160:5:0 +X 3204 . T <*> 0 . DP=19;I16=9,8,0,0,619,22955,0,0,1020,61200,0,0,306,6686,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,234:9:0 0,9,101:3:0 0,15,169:5:0 +X 3205 . C <*> 0 . DP=19;I16=9,9,0,0,672,25340,0,0,1080,64800,0,0,318,6856,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,99:3:0 0,15,157:5:0 +X 3206 . A <*> 0 . DP=19;I16=10,9,0,0,661,23623,0,0,1109,65641,0,0,342,7500,0,0;QS=3,0;MQSB=0.934728;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,91:3:0 0,15,165:5:0 +X 3207 . C <*> 0 . DP=19;I16=9,9,0,0,642,23618,0,0,1080,64800,0,0,316,6912,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,90:3:0 0,15,158:5:0 +X 3208 . A <*> 0 . DP=18;I16=10,8,0,0,619,22023,0,0,1049,62041,0,0,341,7591,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,33,247:11:0 0,9,95:3:0 0,12,142:4:0 +X 3209 . C <*> 0 . DP=19;I16=11,8,0,0,681,24747,0,0,1109,65641,0,0,340,7612,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,106:3:0 0,12,134:4:0 +X 3210 . C <*> 0 . DP=18;I16=11,7,0,0,664,24900,0,0,1049,62041,0,0,340,7602,0,0;QS=3,0;MQSB=0.951002;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,101:3:0 0,12,141:4:0 +X 3211 . A <*> 0 . DP=17;I16=11,6,0,0,645,24627,0,0,989,58441,0,0,341,7611,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,9,106:3:0 0,12,140:4:0 +X 3212 . T <*> 0 . DP=17;I16=10,6,0,0,575,21295,0,0,960,57600,0,0,316,6964,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,222:9:0 0,9,100:3:0 0,12,144:4:0 +X 3213 . A <*> 0 . DP=17;I16=10,6,0,0,597,22631,0,0,960,57600,0,0,316,6962,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,9,117:3:0 0,12,138:4:0 +X 3214 . G <*> 0 . DP=17;I16=11,6,0,0,615,23103,0,0,989,58441,0,0,341,7605,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,9,110:3:0 0,12,134:4:0 +X 3215 . G <*> 0 . DP=17;I16=11,6,0,0,591,21523,0,0,989,58441,0,0,340,7592,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,30,241:10:0 0,9,93:3:0 0,12,128:4:0 +X 3216 . C <*> 0 . DP=17;I16=11,6,0,0,623,23303,0,0,989,58441,0,0,339,7597,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,30,242:10:0 0,9,94:3:0 0,12,138:4:0 +X 3217 . C <*> 0 . DP=17;I16=11,6,0,0,570,19896,0,0,989,58441,0,0,337,7569,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,30,236:10:0 0,9,84:3:0 0,12,123:4:0 +X 3218 . G C,<*> 0 . DP=18;I16=10,7,1,0,547,18185,29,841,1020,61200,29,841,310,6932,24,576;QS=2.91667,0.0833333,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.951002;BQB=1;MQ0F=0 PL:DP:DV 0,4,202,30,205,221:11:1 0,9,96,9,96,96:3:0 0,12,112,12,112,112:4:0 +X 3219 . G A,<*> 0 . DP=18;I16=10,7,1,0,606,22158,19,361,1020,61200,29,841,308,6888,23,529;QS=2.94837,0.0516304,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.951002;BQB=1;MQ0F=0 PL:DP:DV 0,14,234,30,237,243:11:1 0,9,107,9,107,107:3:0 0,12,126,12,126,126:4:0 +X 3220 . G <*> 0 . DP=18;I16=11,7,0,0,631,22827,0,0,1049,62041,0,0,326,7248,0,0;QS=3,0;MQSB=0.951002;MQ0F=0 PL:DP:DV 0,33,252:11:0 0,9,112:3:0 0,12,126:4:0 +X 3221 . C <*> 0 . DP=17;I16=9,7,0,0,598,22586,0,0,960,57600,0,0,301,6659,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,9,103:3:0 0,12,139:4:0 +X 3222 . A <*> 0 . DP=17;I16=10,7,0,0,623,23037,0,0,989,58441,0,0,318,6972,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,100:3:0 0,12,133:4:0 +X 3223 . C <*> 0 . DP=17;I16=10,7,0,0,611,22603,0,0,989,58441,0,0,312,6764,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,96:3:0 0,12,132:4:0 +X 3224 . A <*> 0 . DP=16;I16=10,6,0,0,609,23381,0,0,929,54841,0,0,307,6575,0,0;QS=3,0;MQSB=0.948436;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,9,97:3:0 0,12,141:4:0 +X 3225 . G <*> 0 . DP=17;I16=11,6,0,0,604,22692,0,0,989,58441,0,0,302,6404,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,27,247:9:0 0,12,108:4:0 0,12,134:4:0 +X 3226 . T <*> 0 . DP=18;I16=11,6,0,0,582,20466,0,0,1020,61200,0,0,282,5996,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,224:9:0 0,12,112:4:0 0,12,131:4:0 +X 3227 . G <*> 0 . DP=18;I16=12,5,0,0,618,23008,0,0,989,58441,0,0,270,5496,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,91:3:0 0,12,125:4:0 +X 3228 . G <*> 0 . DP=18;I16=11,6,0,0,611,22581,0,0,1020,61200,0,0,278,5816,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,248:9:0 0,12,118:4:0 0,12,121:4:0 +X 3229 . C <*> 0 . DP=19;I16=12,7,0,0,686,25394,0,0,1109,65641,0,0,289,5925,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,118:4:0 0,12,126:4:0 +X 3230 . T <*> 0 . DP=19;I16=12,6,0,0,669,25441,0,0,1049,62041,0,0,261,5187,0,0;QS=3,0;MQSB=0.961295;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,107:3:0 0,12,139:4:0 +X 3231 . C <*> 0 . DP=19;I16=12,7,0,0,682,25046,0,0,1109,65641,0,0,283,5725,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,112:4:0 0,12,128:4:0 +X 3232 . A <*> 0 . DP=19;I16=11,7,0,0,597,20779,0,0,1080,64800,0,0,270,5564,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,229:10:0 0,12,117:4:0 0,12,132:4:0 +X 3233 . C <*> 0 . DP=19;I16=12,7,0,0,573,18239,0,0,1109,65641,0,0,277,5629,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,33,238:11:0 0,12,91:4:0 0,12,110:4:0 +X 3234 . G T,<*> 0 . DP=19;I16=10,6,1,0,511,17305,22,484,960,57600,29,841,233,4849,8,64;QS=2.93855,0.0614525,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.955563;BQB=1;MQ0F=0 PL:DP:DV 0,11,222,30,225,234:11:1 0,6,63,6,63,63:2:0 0,12,100,12,100,100:4:0 +X 3235 . C <*> 0 . DP=18;I16=12,6,0,0,625,22649,0,0,1049,62041,0,0,274,5582,0,0;QS=3,0;MQSB=0.961295;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,12,119:4:0 0,12,123:4:0 +X 3236 . C <*> 0 . DP=18;I16=12,6,0,0,668,25124,0,0,1049,62041,0,0,273,5567,0,0;QS=3,0;MQSB=0.961295;MQ0F=0 PL:DP:DV 0,30,244:10:0 0,12,137:4:0 0,12,134:4:0 +X 3237 . T <*> 0 . DP=17;I16=11,6,0,0,589,21235,0,0,989,58441,0,0,273,5573,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,27,230:9:0 0,12,102:4:0 0,12,136:4:0 +X 3238 . G <*> 0 . DP=17;I16=11,6,0,0,609,22539,0,0,989,58441,0,0,273,5599,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,27,243:9:0 0,12,104:4:0 0,12,129:4:0 +X 3239 . T <*> 0 . DP=17;I16=11,6,0,0,574,20204,0,0,989,58441,0,0,273,5645,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,27,220:9:0 0,12,107:4:0 0,12,131:4:0 +X 3240 . A <*> 0 . DP=19;I16=12,7,0,0,624,21552,0,0,1109,65641,0,0,273,5711,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,33,248:11:0 0,12,101:4:0 0,12,132:4:0 +X 3241 . A <*> 0 . DP=19;I16=11,6,0,0,619,23121,0,0,1020,61200,0,0,249,5173,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,9,96:3:0 0,12,143:4:0 +X 3242 . T <*> 0 . DP=19;I16=12,7,0,0,655,23279,0,0,1140,68400,0,0,277,5911,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,12,104:4:0 0,15,152:5:0 +X 3243 . C <*> 0 . DP=19;I16=12,7,0,0,682,25216,0,0,1140,68400,0,0,281,6047,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,111:4:0 0,15,148:5:0 +X 3244 . C <*> 0 . DP=18;I16=11,6,0,0,587,21119,0,0,1020,61200,0,0,281,6139,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,12,116:4:0 0,15,142:5:0 +X 3245 . C <*> 0 . DP=17;I16=10,7,0,0,631,23851,0,0,1020,61200,0,0,290,6282,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,12,126:4:0 0,12,131:4:0 +X 3246 . A <*> 0 . DP=17;I16=10,7,0,0,646,24716,0,0,1020,61200,0,0,295,6427,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,12,129:4:0 0,12,139:4:0 +X 3247 . G <*> 0 . DP=17;I16=10,7,0,0,606,22554,0,0,1020,61200,0,0,300,6590,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,12,92:4:0 0,12,133:4:0 +X 3248 . C <*> 0 . DP=16;I16=10,6,0,0,603,23115,0,0,960,57600,0,0,306,6770,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,9,99:3:0 0,12,132:4:0 +X 3249 . C <*> 0 . DP=16;I16=10,6,0,0,587,21913,0,0,960,57600,0,0,311,6917,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,246:9:0 0,9,99:3:0 0,12,133:4:0 +X 3250 . C <*> 0 . DP=16;I16=10,6,0,0,616,24080,0,0,960,57600,0,0,316,7082,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,9,95:3:0 0,12,137:4:0 +X 3251 . T <*> 0 . DP=16;I16=10,6,0,0,585,22193,0,0,960,57600,0,0,319,7165,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,9,104:3:0 0,12,135:4:0 +X 3252 . T <*> 0 . DP=16;I16=10,6,0,0,553,19781,0,0,960,57600,0,0,321,7215,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,9,84:3:0 0,12,126:4:0 +X 3253 . T <*> 0 . DP=16;I16=10,6,0,0,589,21933,0,0,960,57600,0,0,323,7281,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,245:9:0 0,9,102:3:0 0,12,132:4:0 +X 3254 . G <*> 0 . DP=17;I16=10,7,0,0,631,23737,0,0,1020,61200,0,0,325,7363,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,9,100:3:0 0,15,154:5:0 +X 3255 . G <*> 0 . DP=16;I16=9,7,0,0,554,20088,0,0,960,57600,0,0,328,7410,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,243:9:0 0,9,93:3:0 0,12,120:4:0 +X 3256 . G <*> 0 . DP=16;I16=8,7,0,0,571,21985,0,0,900,54000,0,0,306,6846,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,6,62:2:0 0,12,142:4:0 +X 3257 . A <*> 0 . DP=16;I16=9,7,0,0,585,21881,0,0,960,57600,0,0,334,7546,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,243:9:0 0,9,94:3:0 0,12,144:4:0 +X 3258 . G <*> 0 . DP=17;I16=9,8,0,0,647,25407,0,0,1020,61200,0,0,337,7635,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,81:3:0 0,12,146:4:0 +X 3259 . G <*> 0 . DP=17;I16=9,8,0,0,605,22237,0,0,1020,61200,0,0,341,7739,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,79:3:0 0,12,139:4:0 +X 3260 . C <*> 0 . DP=17;I16=9,7,0,0,616,23908,0,0,960,57600,0,0,319,7183,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,6,64:2:0 0,12,133:4:0 +X 3261 . C <*> 0 . DP=18;I16=9,9,0,0,655,24475,0,0,1080,64800,0,0,347,7891,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,90:3:0 0,12,138:4:0 +X 3262 . A <*> 0 . DP=19;I16=10,9,0,0,712,27036,0,0,1140,68400,0,0,351,7989,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,123:4:0 0,12,148:4:0 +X 3263 . G <*> 0 . DP=19;I16=10,9,0,0,715,27317,0,0,1140,68400,0,0,356,8104,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,116:4:0 0,12,146:4:0 +X 3264 . G <*> 0 . DP=19;I16=10,9,0,0,676,24734,0,0,1140,68400,0,0,361,8237,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,93:4:0 0,12,143:4:0 +X 3265 . G <*> 0 . DP=19;I16=10,9,0,0,701,26199,0,0,1140,68400,0,0,365,8339,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,109:4:0 0,12,137:4:0 +X 3266 . T <*> 0 . DP=19;I16=9,9,0,0,597,20769,0,0,1080,64800,0,0,357,8229,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,82:4:0 0,9,113:3:0 +X 3267 . G <*> 0 . DP=19;I16=10,9,0,0,659,24285,0,0,1140,68400,0,0,367,8299,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,76:4:0 0,12,133:4:0 +X 3268 . G <*> 0 . DP=19;I16=10,9,0,0,668,24306,0,0,1140,68400,0,0,367,8255,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,92:4:0 0,12,142:4:0 +X 3269 . G <*> 0 . DP=19;I16=10,9,0,0,714,27122,0,0,1140,68400,0,0,367,8227,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,115:4:0 0,12,137:4:0 +X 3270 . T <*> 0 . DP=20;I16=10,9,0,0,606,20364,0,0,1140,68400,0,0,361,8141,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,251:11:0 0,12,83:4:0 0,12,136:4:0 +X 3271 . G <*> 0 . DP=19;I16=10,9,0,0,709,26993,0,0,1140,68400,0,0,362,8108,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,100:4:0 0,12,143:4:0 +X 3272 . G <*> 0 . DP=19;I16=10,9,0,0,672,24398,0,0,1140,68400,0,0,363,8093,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,97:4:0 0,12,140:4:0 +X 3273 . A <*> 0 . DP=20;I16=10,10,0,0,735,27355,0,0,1200,72000,0,0,363,8047,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,153:5:0 0,12,147:4:0 +X 3274 . T <*> 0 . DP=19;I16=9,10,0,0,699,26089,0,0,1140,68400,0,0,365,8021,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,142:5:0 0,12,149:4:0 +X 3275 . C <*> 0 . DP=19;I16=9,10,0,0,727,28197,0,0,1140,68400,0,0,367,8015,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,137:5:0 0,12,139:4:0 +X 3276 . A <*> 0 . DP=19;I16=9,10,0,0,681,25123,0,0,1140,68400,0,0,369,8029,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,15,150:5:0 0,12,141:4:0 +X 3277 . C <*> 0 . DP=19;I16=9,10,0,0,733,28485,0,0,1140,68400,0,0,371,8063,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,153:5:0 0,12,146:4:0 +X 3278 . T <*> 0 . DP=19;I16=9,10,0,0,737,28901,0,0,1140,68400,0,0,373,8117,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,168:5:0 0,12,153:4:0 +X 3279 . T <*> 0 . DP=19;I16=9,10,0,0,714,27132,0,0,1140,68400,0,0,375,8191,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,148:5:0 0,12,150:4:0 +X 3280 . G <*> 0 . DP=20;I16=9,11,0,0,758,29178,0,0,1200,72000,0,0,376,8234,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,143:5:0 0,12,146:4:0 +X 3281 . A <*> 0 . DP=21;I16=10,11,0,0,822,32654,0,0,1260,75600,0,0,378,8296,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,179:6:0 0,12,157:4:0 +X 3282 . G <*> 0 . DP=21;I16=10,11,0,0,815,32059,0,0,1260,75600,0,0,381,8379,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,173:6:0 0,12,150:4:0 +X 3283 . G <*> 0 . DP=21;I16=10,11,0,0,790,30110,0,0,1260,75600,0,0,384,8484,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,161:6:0 0,12,146:4:0 +X 3284 . T <*> 0 . DP=21;I16=10,11,0,0,748,27628,0,0,1260,75600,0,0,385,8511,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,155:6:0 0,12,146:4:0 +X 3285 . C <*> 0 . DP=21;I16=10,11,0,0,776,29442,0,0,1260,75600,0,0,386,8560,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,169:6:0 0,12,143:4:0 +X 3286 . A <*> 0 . DP=21;I16=10,11,0,0,826,32732,0,0,1260,75600,0,0,387,8631,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,187:6:0 0,12,153:4:0 +X 3287 . G <*> 0 . DP=21;I16=10,11,0,0,804,31448,0,0,1260,75600,0,0,387,8673,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,164:6:0 0,12,150:4:0 +X 3288 . G <*> 0 . DP=22;I16=10,11,0,0,754,27862,0,0,1260,75600,0,0,379,8635,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,141:5:0 0,15,164:5:0 +X 3289 . A <*> 0 . DP=24;I16=13,11,0,0,897,34439,0,0,1440,86400,0,0,386,8714,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,166:6:0 0,15,178:5:0 +X 3290 . G <*> 0 . DP=23;I16=12,10,0,0,832,31964,0,0,1320,79200,0,0,380,8684,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,112:4:0 0,15,168:5:0 +X 3291 . T <*> 0 . DP=22;I16=11,9,0,0,707,25481,0,0,1200,72000,0,0,358,8112,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,95:3:0 0,15,168:5:0 +X 3292 . T <*> 0 . DP=22;I16=13,9,0,0,783,28439,0,0,1320,79200,0,0,397,8929,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,127:5:0 0,15,164:5:0 +X 3293 . C <*> 0 . DP=22;I16=13,9,0,0,852,33430,0,0,1320,79200,0,0,400,8992,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,136:5:0 0,15,170:5:0 +X 3294 . A <*> 0 . DP=22;I16=13,9,0,0,818,30684,0,0,1320,79200,0,0,403,9077,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,145:5:0 0,15,162:5:0 +X 3295 . A <*> 0 . DP=22;I16=14,8,0,0,820,31004,0,0,1320,79200,0,0,407,9183,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,140:5:0 0,12,143:4:0 +X 3296 . G <*> 0 . DP=22;I16=14,8,0,0,837,32209,0,0,1320,79200,0,0,411,9259,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,133:5:0 0,12,140:4:0 +X 3297 . A <*> 0 . DP=22;I16=14,8,0,0,787,28771,0,0,1320,79200,0,0,415,9355,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,134:5:0 0,12,140:4:0 +X 3298 . C <*> 0 . DP=22;I16=13,9,0,0,826,31506,0,0,1320,79200,0,0,420,9470,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,113:4:0 0,12,135:4:0 +X 3299 . C <*> 0 . DP=22;I16=13,9,0,0,857,33829,0,0,1320,79200,0,0,425,9553,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,117:4:0 0,12,140:4:0 +X 3300 . A <*> 0 . DP=22;I16=13,9,0,0,861,33855,0,0,1320,79200,0,0,430,9654,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,134:4:0 0,12,144:4:0 +X 3301 . G <*> 0 . DP=22;I16=13,9,0,0,869,34495,0,0,1320,79200,0,0,433,9675,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,131:4:0 0,12,141:4:0 +X 3302 . C <*> 0 . DP=23;I16=14,9,0,0,863,32885,0,0,1380,82800,0,0,436,9718,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,115:4:0 0,15,155:5:0 +X 3303 . C <*> 0 . DP=23;I16=14,9,0,0,887,34451,0,0,1380,82800,0,0,440,9784,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,125:4:0 0,15,153:5:0 +X 3304 . T <*> 0 . DP=23;I16=14,9,0,0,886,34388,0,0,1380,82800,0,0,443,9825,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,134:4:0 0,15,167:5:0 +X 3305 . G <*> 0 . DP=23;I16=14,9,0,0,878,33846,0,0,1380,82800,0,0,446,9892,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,119:4:0 0,15,151:5:0 +X 3306 . G <*> 0 . DP=23;I16=14,9,0,0,886,34386,0,0,1380,82800,0,0,448,9934,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,127:4:0 0,15,150:5:0 +X 3307 . C <*> 0 . DP=23;I16=14,8,0,0,812,30814,0,0,1320,79200,0,0,428,9508,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,116:4:0 0,15,153:5:0 +X 3308 . C <*> 0 . DP=23;I16=14,9,0,0,835,31367,0,0,1380,82800,0,0,450,9986,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,118:4:0 0,15,151:5:0 +X 3309 . A <*> 0 . DP=23;I16=14,9,0,0,875,33541,0,0,1380,82800,0,0,451,9995,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,128:4:0 0,15,162:5:0 +X 3310 . A <*> 0 . DP=24;I16=15,9,0,0,882,32950,0,0,1440,86400,0,0,453,10027,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,152:5:0 0,15,164:5:0 +X 3311 . C <*> 0 . DP=24;I16=15,9,0,0,913,35161,0,0,1440,86400,0,0,456,10084,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,145:5:0 0,15,157:5:0 +X 3312 . A <*> 0 . DP=26;I16=16,9,0,0,950,36336,0,0,1500,90000,0,0,459,10167,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,153:5:0 0,15,160:5:0 +X 3313 . T <*> 0 . DP=26;I16=16,10,0,0,987,37617,0,0,1560,93600,0,0,488,10902,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,180:6:0 0,15,161:5:0 +X 3314 . G <*> 0 . DP=26;I16=16,10,0,0,1007,39401,0,0,1560,93600,0,0,491,10989,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,171:6:0 0,15,161:5:0 +X 3315 . G <*> 0 . DP=26;I16=15,10,0,0,945,36073,0,0,1500,90000,0,0,484,10866,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,172:6:0 0,15,159:5:0 +X 3316 . T <*> 0 . DP=26;I16=15,10,0,0,853,29881,0,0,1500,90000,0,0,464,10216,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,157:6:0 0,12,122:4:0 +X 3317 . G <*> 0 . DP=27;I16=16,11,0,0,997,37431,0,0,1620,97200,0,0,488,10806,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,164:6:0 0,18,167:6:0 +X 3318 . A <*> 0 . DP=26;I16=15,10,0,0,904,33212,0,0,1500,90000,0,0,481,10699,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,155:5:0 0,18,185:6:0 +X 3319 . A <*> 0 . DP=25;I16=15,10,0,0,912,34090,0,0,1500,90000,0,0,482,10682,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,139:5:0 0,18,188:6:0 +X 3320 . A <*> 0 . DP=25;I16=15,10,0,0,888,32722,0,0,1500,90000,0,0,483,10691,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,133:5:0 0,18,178:6:0 +X 3321 . C <*> 0 . DP=25;I16=14,10,0,0,900,34142,0,0,1440,86400,0,0,471,10531,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,157:5:0 0,18,186:6:0 +X 3322 . C <*> 0 . DP=25;I16=15,10,0,0,980,38582,0,0,1500,90000,0,0,483,10683,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,164:5:0 0,18,198:6:0 +X 3323 . C <*> 0 . DP=25;I16=15,10,0,0,922,34948,0,0,1500,90000,0,0,483,10715,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,146:5:0 0,18,201:6:0 +X 3324 . C <*> 0 . DP=25;I16=15,10,0,0,869,31271,0,0,1500,90000,0,0,482,10720,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,142:5:0 0,18,186:6:0 +X 3325 . G <*> 0 . DP=25;I16=15,10,0,0,827,28293,0,0,1500,90000,0,0,481,10747,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,134:5:0 0,18,163:6:0 +X 3326 . T <*> 0 . DP=24;I16=13,10,0,0,842,31362,0,0,1380,82800,0,0,464,10506,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,150:5:0 0,18,186:6:0 +X 3327 . C <*> 0 . DP=24;I16=14,10,0,0,938,37076,0,0,1440,86400,0,0,481,10863,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,154:5:0 0,18,190:6:0 +X 3328 . T <*> 0 . DP=25;I16=15,10,0,0,959,37033,0,0,1500,90000,0,0,480,10900,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,163:5:0 0,21,213:7:0 +X 3329 . A <*> 0 . DP=24;I16=15,9,0,0,888,33082,0,0,1440,86400,0,0,481,10955,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,149:5:0 0,21,207:7:0 +X 3330 . C <*> 0 . DP=25;I16=16,9,0,0,954,37064,0,0,1500,90000,0,0,481,10979,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,168:5:0 0,21,203:7:0 +X 3331 . T <*> 0 . DP=25;I16=16,9,0,0,960,37332,0,0,1500,90000,0,0,482,11024,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,165:5:0 0,21,224:7:0 +X 3332 . A <*> 0 . DP=25;I16=16,9,0,0,933,35065,0,0,1500,90000,0,0,483,11091,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,165:5:0 0,21,211:7:0 +X 3333 . A <*> 0 . DP=26;I16=16,10,0,0,976,37344,0,0,1560,93600,0,0,483,11131,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,166:5:0 0,24,241:8:0 +X 3334 . A <*> 0 . DP=25;I16=15,10,0,0,972,38210,0,0,1500,90000,0,0,485,11195,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,168:5:0 0,24,241:8:0 +X 3335 . A <*> 0 . DP=25;I16=15,10,0,0,970,38200,0,0,1500,90000,0,0,486,11232,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,170:5:0 0,24,239:8:0 +X 3336 . A <*> 0 . DP=25;I16=15,10,0,0,929,35277,0,0,1500,90000,0,0,485,11191,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,166:5:0 0,24,232:8:0 +X 3337 . T <*> 0 . DP=25;I16=15,10,0,0,902,32856,0,0,1500,90000,0,0,484,11172,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,157:5:0 0,24,224:8:0 +X 3338 . A <*> 0 . DP=25;I16=15,10,0,0,892,32056,0,0,1500,90000,0,0,481,11075,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,153:5:0 0,24,214:8:0 +X 3339 . C <*> 0 . DP=25;I16=15,10,0,0,964,37444,0,0,1500,90000,0,0,478,11000,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,167:5:0 0,24,232:8:0 +X 3340 . A <*> 0 . DP=23;I16=14,9,0,0,890,34616,0,0,1380,82800,0,0,477,10945,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,173:5:0 0,24,233:8:0 +X 3341 . A <*> 0 . DP=23;I16=14,9,0,0,885,34459,0,0,1380,82800,0,0,476,10908,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,167:5:0 0,24,238:8:0 +X 3342 . A <*> 0 . DP=23;I16=14,9,0,0,862,33262,0,0,1380,82800,0,0,475,10889,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,170:5:0 0,24,240:8:0 +X 3343 . A <*> 0 . DP=22;I16=13,9,0,0,866,34280,0,0,1320,79200,0,0,474,10836,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,173:5:0 0,21,231:7:0 +X 3344 . A <*> 0 . DP=22;I16=13,9,0,0,859,33731,0,0,1320,79200,0,0,473,10797,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,173:5:0 0,21,226:7:0 +X 3345 . T <*> 0 . DP=22;I16=13,9,0,0,822,31100,0,0,1320,79200,0,0,472,10772,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,254:10:0 0,15,159:5:0 0,21,220:7:0 +X 3346 . T <*> 0 . DP=22;I16=13,9,0,0,847,32679,0,0,1320,79200,0,0,470,10712,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,168:5:0 0,21,221:7:0 +X 3347 . A <*> 0 . DP=23;I16=14,9,0,0,888,34650,0,0,1380,82800,0,0,468,10668,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,185:6:0 0,21,227:7:0 +X 3348 . G <*> 0 . DP=23;I16=14,9,0,0,873,33609,0,0,1380,82800,0,0,467,10641,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,171:6:0 0,21,219:7:0 +X 3349 . C <*> 0 . DP=24;I16=14,9,0,0,815,29785,0,0,1380,82800,0,0,465,10583,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,166:6:0 0,21,205:7:0 +X 3350 . C <*> 0 . DP=24;I16=14,10,0,0,939,37249,0,0,1440,86400,0,0,464,10546,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,209:7:0 0,21,220:7:0 +X 3351 . T <*> 0 . DP=24;I16=14,10,0,0,943,37255,0,0,1440,86400,0,0,463,10531,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,210:7:0 0,21,228:7:0 +X 3352 . G <*> 0 . DP=24;I16=14,10,0,0,887,33267,0,0,1440,86400,0,0,462,10538,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,192:7:0 0,21,214:7:0 +X 3353 . G <*> 0 . DP=24;I16=14,10,0,0,864,32092,0,0,1440,86400,0,0,461,10567,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,190:7:0 0,21,214:7:0 +X 3354 . C <*> 0 . DP=24;I16=14,10,0,0,848,30714,0,0,1440,86400,0,0,459,10567,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,178:7:0 0,21,209:7:0 +X 3355 . G <*> 0 . DP=23;I16=14,9,0,0,738,24386,0,0,1380,82800,0,0,457,10537,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,232:10:0 0,21,170:7:0 0,18,166:6:0 +X 3356 . T <*> 0 . DP=23;I16=14,9,0,0,847,31689,0,0,1380,82800,0,0,454,10476,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,191:7:0 0,18,195:6:0 +X 3357 . G <*> 0 . DP=23;I16=14,9,0,0,863,32919,0,0,1380,82800,0,0,449,10335,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,193:7:0 0,18,192:6:0 +X 3358 . G <*> 0 . DP=22;I16=14,8,0,0,810,30184,0,0,1320,79200,0,0,445,10215,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,21,200:7:0 0,18,187:6:0 +X 3359 . T <*> 0 . DP=23;I16=13,8,0,0,743,26737,0,0,1260,75600,0,0,404,9318,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,21,194:7:0 0,15,162:5:0 +X 3360 . G <*> 0 . DP=23;I16=15,8,0,0,822,30058,0,0,1380,82800,0,0,436,9932,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,186:7:0 0,18,175:6:0 +X 3361 . G <*> 0 . DP=22;I16=15,7,0,0,751,26793,0,0,1320,79200,0,0,433,9819,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,218:9:0 0,21,187:7:0 0,18,175:6:0 +X 3362 . C <*> 0 . DP=22;I16=15,7,0,0,768,27462,0,0,1320,79200,0,0,430,9724,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,230:9:0 0,21,178:7:0 0,18,173:6:0 +X 3363 . G <*> 0 . DP=21;I16=14,7,0,0,662,21572,0,0,1260,75600,0,0,428,9646,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,194:9:0 0,18,155:6:0 0,18,161:6:0 +X 3364 . C <*> 0 . DP=21;I16=14,7,0,0,818,32184,0,0,1260,75600,0,0,423,9437,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,18,191:6:0 0,18,194:6:0 +X 3365 . A <*> 0 . DP=21;I16=14,7,0,0,791,29983,0,0,1260,75600,0,0,418,9250,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,226:9:0 0,18,186:6:0 0,18,190:6:0 +X 3366 . T <*> 0 . DP=21;I16=14,7,0,0,759,28053,0,0,1260,75600,0,0,413,9085,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,221:9:0 0,18,185:6:0 0,18,177:6:0 +X 3367 . G <*> 0 . DP=21;I16=14,7,0,0,767,28539,0,0,1260,75600,0,0,408,8942,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,235:9:0 0,18,185:6:0 0,18,169:6:0 +X 3368 . C <*> 0 . DP=21;I16=14,7,0,0,807,31329,0,0,1260,75600,0,0,403,8821,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,245:9:0 0,18,181:6:0 0,18,189:6:0 +X 3369 . C <*> 0 . DP=21;I16=14,7,0,0,789,30271,0,0,1260,75600,0,0,398,8722,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,18,186:6:0 0,18,193:6:0 +X 3370 . T <*> 0 . DP=21;I16=13,7,0,0,798,31960,0,0,1200,72000,0,0,392,8596,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,18,201:6:0 0,15,178:5:0 +X 3371 . G <*> 0 . DP=20;I16=13,7,0,0,739,27875,0,0,1200,72000,0,0,387,8493,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,18,173:6:0 0,15,169:5:0 +X 3372 . T <*> 0 . DP=20;I16=13,6,0,0,693,25677,0,0,1140,68400,0,0,359,7883,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,220:9:0 0,15,154:5:0 0,15,167:5:0 +X 3373 . A <*> 0 . DP=20;I16=13,7,0,0,729,27019,0,0,1200,72000,0,0,375,8253,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,226:9:0 0,18,162:6:0 0,15,174:5:0 +X 3374 . A <*> 0 . DP=19;I16=13,6,0,0,719,27437,0,0,1140,68400,0,0,369,8115,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,225:9:0 0,15,167:5:0 0,15,164:5:0 +X 3375 . T <*> 0 . DP=20;I16=12,6,0,0,683,26039,0,0,1080,64800,0,0,337,7321,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,15,155:5:0 0,15,172:5:0 +X 3376 . C <*> 0 . DP=20;I16=13,7,0,0,739,27867,0,0,1200,72000,0,0,356,7796,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,254:10:0 0,15,146:5:0 0,15,173:5:0 +X 3377 . C <*> 0 . DP=20;I16=13,7,0,0,741,27905,0,0,1200,72000,0,0,350,7666,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,15,149:5:0 0,15,173:5:0 +X 3378 . C <*> 0 . DP=20;I16=13,7,0,0,775,30179,0,0,1200,72000,0,0,343,7507,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,161:5:0 0,15,172:5:0 +X 3379 . A <*> 0 . DP=20;I16=13,7,0,0,736,27530,0,0,1200,72000,0,0,336,7370,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,245:10:0 0,15,157:5:0 0,15,169:5:0 +X 3380 . G <*> 0 . DP=19;I16=13,6,0,0,729,28249,0,0,1140,68400,0,0,330,7254,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,15,157:5:0 0,15,178:5:0 +X 3381 . C <*> 0 . DP=19;I16=13,6,0,0,742,29288,0,0,1140,68400,0,0,324,7158,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,15,155:5:0 0,15,178:5:0 +X 3382 . T <*> 0 . DP=17;I16=12,5,0,0,649,25245,0,0,1020,61200,0,0,320,7080,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,222:9:0 0,9,105:3:0 0,15,184:5:0 +X 3383 . A <*> 0 . DP=17;I16=12,4,0,0,556,19808,0,0,960,57600,0,0,291,6393,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,196:9:0 0,6,71:2:0 0,15,167:5:0 +X 3384 . C <*> 0 . DP=19;I16=14,5,0,0,701,26181,0,0,1140,68400,0,0,311,6923,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,235:10:0 0,9,98:3:0 0,18,187:6:0 +X 3385 . T <*> 0 . DP=19;I16=14,5,0,0,730,28456,0,0,1140,68400,0,0,307,6797,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,237:10:0 0,9,109:3:0 0,18,195:6:0 +X 3386 . T <*> 0 . DP=19;I16=14,5,0,0,642,22450,0,0,1140,68400,0,0,302,6642,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,197:10:0 0,9,104:3:0 0,18,188:6:0 +X 3387 . G <*> 0 . DP=20;I16=14,6,0,0,723,26761,0,0,1200,72000,0,0,296,6460,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,230:10:0 0,9,105:3:0 0,21,210:7:0 +X 3388 . G <*> 0 . DP=20;I16=14,6,0,0,705,25891,0,0,1200,72000,0,0,291,6303,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,225:10:0 0,9,109:3:0 0,21,202:7:0 +X 3389 . G <*> 0 . DP=18;I16=10,7,0,0,617,22635,0,0,1020,61200,0,0,270,5808,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,190:7:0 0,9,105:3:0 0,21,207:7:0 +X 3390 . A <*> 0 . DP=18;I16=11,7,0,0,631,22681,0,0,1080,64800,0,0,288,6056,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,200:8:0 0,9,105:3:0 0,21,198:7:0 +X 3391 . A <*> 0 . DP=18;I16=11,7,0,0,663,24951,0,0,1080,64800,0,0,287,5965,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,192:8:0 0,9,113:3:0 0,21,224:7:0 +X 3392 . G <*> 0 . DP=18;I16=11,7,0,0,666,25104,0,0,1080,64800,0,0,286,5896,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,211:8:0 0,9,103:3:0 0,21,216:7:0 +X 3393 . C <*> 0 . DP=18;I16=11,7,0,0,686,26472,0,0,1080,64800,0,0,284,5800,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,222:8:0 0,9,106:3:0 0,21,214:7:0 +X 3394 . T <*> 0 . DP=18;I16=11,7,0,0,699,27481,0,0,1080,64800,0,0,282,5728,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,219:8:0 0,9,114:3:0 0,21,222:7:0 +X 3395 . G <*> 0 . DP=17;I16=10,7,0,0,656,25512,0,0,1020,61200,0,0,281,5679,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,205:7:0 0,9,105:3:0 0,21,222:7:0 +X 3396 . A <*> 0 . DP=17;I16=10,7,0,0,644,25446,0,0,1020,61200,0,0,280,5652,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,182:7:0 0,9,119:3:0 0,21,232:7:0 +X 3397 . G <*> 0 . DP=17;I16=10,7,0,0,633,23895,0,0,1020,61200,0,0,279,5647,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,193:7:0 0,9,107:3:0 0,21,218:7:0 +X 3398 . G <*> 0 . DP=16;I16=10,6,0,0,610,23380,0,0,960,57600,0,0,279,5663,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,170:6:0 0,9,110:3:0 0,21,215:7:0 +X 3399 . G <*> 0 . DP=17;I16=10,6,0,0,585,21729,0,0,960,57600,0,0,270,5618,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,147:5:0 0,12,122:4:0 0,21,216:7:0 +X 3400 . A <*> 0 . DP=17;I16=10,6,0,0,576,21400,0,0,960,57600,0,0,264,5500,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,136:5:0 0,12,131:4:0 0,21,213:7:0 +X 3401 . T <*> 0 . DP=17;I16=11,6,0,0,605,22159,0,0,1020,61200,0,0,280,5784,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,146:6:0 0,12,131:4:0 0,21,216:7:0 +X 3402 . G <*> 0 . DP=17;I16=11,6,0,0,638,24150,0,0,1020,61200,0,0,280,5832,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,172:6:0 0,12,130:4:0 0,21,213:7:0 +X 3403 . A <*> 0 . DP=16;I16=9,6,0,0,579,22815,0,0,900,54000,0,0,276,5874,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,139:5:0 0,12,140:4:0 0,18,205:6:0 +X 3404 . G <*> 0 . DP=16;I16=10,6,0,0,564,20652,0,0,960,57600,0,0,281,5935,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,148:6:0 0,12,131:4:0 0,18,186:6:0 +X 3405 . A <*> 0 . DP=16;I16=10,6,0,0,560,20158,0,0,960,57600,0,0,281,5991,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,157:6:0 0,12,124:4:0 0,18,179:6:0 +X 3406 . A <*> 0 . DP=16;I16=10,6,0,0,568,20556,0,0,960,57600,0,0,281,6067,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,150:6:0 0,12,129:4:0 0,18,186:6:0 +X 3407 . C <*> 0 . DP=17;I16=11,6,0,0,591,21225,0,0,1020,61200,0,0,281,6163,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,178:7:0 0,12,106:4:0 0,18,183:6:0 +X 3408 . T <*> 0 . DP=17;I16=11,6,0,0,632,23754,0,0,1020,61200,0,0,282,6280,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,177:7:0 0,12,133:4:0 0,18,189:6:0 +X 3409 . G <*> 0 . DP=16;I16=10,6,0,0,599,22667,0,0,960,57600,0,0,283,6369,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,172:6:0 0,12,119:4:0 0,18,192:6:0 +X 3410 . C <*> 0 . DP=16;I16=10,6,0,0,585,21685,0,0,960,57600,0,0,282,6378,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,174:6:0 0,12,126:4:0 0,18,176:6:0 +X 3411 . T <*> 0 . DP=15;I16=9,6,0,0,578,22492,0,0,900,54000,0,0,282,6404,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,165:6:0 0,9,114:3:0 0,18,196:6:0 +X 3412 . T <*> 0 . DP=15;I16=9,6,0,0,546,20202,0,0,900,54000,0,0,283,6445,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,148:5:0 0,12,120:4:0 0,18,189:6:0 +X 3413 . G <*> 0 . DP=15;I16=9,6,0,0,559,21023,0,0,900,54000,0,0,283,6401,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,158:5:0 0,12,124:4:0 0,18,184:6:0 +X 3414 . A <*> 0 . DP=15;I16=9,6,0,0,512,17878,0,0,900,54000,0,0,283,6373,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,148:5:0 0,12,116:4:0 0,18,166:6:0 +X 3415 . A <*> 0 . DP=16;I16=9,7,0,0,544,19656,0,0,960,57600,0,0,282,6310,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,142:5:0 0,12,132:4:0 0,21,179:7:0 +X 3416 . C <*> 0 . DP=16;I16=9,7,0,0,562,20168,0,0,960,57600,0,0,282,6262,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,143:5:0 0,12,127:4:0 0,21,191:7:0 +X 3417 . C <*> 0 . DP=16;I16=9,7,0,0,566,20666,0,0,960,57600,0,0,282,6230,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,147:5:0 0,12,126:4:0 0,21,192:7:0 +X 3418 . T <*> 0 . DP=17;I16=10,5,0,0,557,21637,0,0,900,54000,0,0,268,5988,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,150:5:0 0,15,148:5:0 0,15,176:5:0 +X 3419 . G <*> 0 . DP=17;I16=10,7,0,0,594,21642,0,0,1020,61200,0,0,310,6836,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,161:6:0 0,15,140:5:0 0,18,190:6:0 +X 3420 . G <*> 0 . DP=17;I16=10,7,0,0,596,21580,0,0,1020,61200,0,0,312,6850,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,172:6:0 0,15,132:5:0 0,18,188:6:0 +X 3421 . G <*> 0 . DP=18;I16=10,8,0,0,633,22781,0,0,1049,62041,0,0,314,6880,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,21,184:7:0 0,15,138:5:0 0,18,191:6:0 +X 3422 . A <*> 0 . DP=18;I16=9,8,0,0,576,20954,0,0,989,58441,0,0,302,6702,0,0;QS=3,0;MQSB=0.91051;MQ0F=0 PL:DP:DV 0,18,167:6:0 0,15,130:5:0 0,18,188:6:0 +X 3423 . G <*> 0 . DP=18;I16=9,9,0,0,651,24391,0,0,1049,62041,0,0,305,6747,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,21,200:7:0 0,15,149:5:0 0,18,183:6:0 +X 3424 . G <*> 0 . DP=18;I16=8,8,0,0,555,20175,0,0,929,54841,0,0,275,6105,0,0;QS=3,0;MQSB=0.915545;MQ0F=0 PL:DP:DV 0,18,161:6:0 0,15,141:5:0 0,15,169:5:0 +X 3425 . C <*> 0 . DP=18;I16=9,8,0,0,594,21676,0,0,1020,61200,0,0,307,6779,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,168:6:0 0,15,142:5:0 0,18,186:6:0 +X 3426 . A <*> 0 . DP=18;I16=9,8,0,0,633,23967,0,0,1020,61200,0,0,308,6774,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,172:6:0 0,15,151:5:0 0,18,202:6:0 +X 3427 . G <*> 0 . DP=18;I16=9,9,0,0,655,24639,0,0,1049,62041,0,0,315,6823,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,21,209:7:0 0,15,144:5:0 0,18,184:6:0 +X 3428 . A <*> 0 . DP=18;I16=9,7,0,0,573,21235,0,0,960,57600,0,0,305,6793,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,158:5:0 0,15,147:5:0 0,18,178:6:0 +X 3429 . C <*> 0 . DP=17;I16=8,9,0,0,516,16610,0,0,989,58441,0,0,320,6930,0,0;QS=3,0;MQSB=0.928603;MQ0F=0 PL:DP:DV 0,21,176:7:0 0,15,125:5:0 0,15,124:5:0 +X 3430 . G <*> 0 . DP=18;I16=9,9,0,0,539,17155,0,0,1049,62041,0,0,323,7011,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,24,181:8:0 0,15,113:5:0 0,15,144:5:0 +X 3431 . T <*> 0 . DP=18;I16=9,9,0,0,651,24101,0,0,1049,62041,0,0,327,7111,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,24,210:8:0 0,15,139:5:0 0,15,166:5:0 +X 3432 . T <*> 0 . DP=18;I16=8,9,0,0,577,20601,0,0,989,58441,0,0,306,6606,0,0;QS=3,0;MQSB=0.928603;MQ0F=0 PL:DP:DV 0,21,162:7:0 0,15,144:5:0 0,15,165:5:0 +X 3433 . G <*> 0 . DP=18;I16=9,9,0,0,623,22589,0,0,1049,62041,0,0,334,7320,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,24,199:8:0 0,15,138:5:0 0,15,164:5:0 +X 3434 . C <*> 0 . DP=18;I16=10,7,0,0,582,20838,0,0,1020,61200,0,0,324,7208,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,208:8:0 0,15,130:5:0 0,12,137:4:0 +X 3435 . A <*> 0 . DP=18;I16=10,8,0,0,595,21619,0,0,1049,62041,0,0,341,7453,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,27,185:9:0 0,15,150:5:0 0,12,151:4:0 +X 3436 . G <*> 0 . DP=18;I16=10,8,0,0,617,22277,0,0,1049,62041,0,0,345,7549,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,27,218:9:0 0,15,146:5:0 0,12,133:4:0 +X 3437 . T G,<*> 0 . DP=18;I16=10,7,0,1,594,21168,16,256,1020,61200,29,841,333,7409,16,256;QS=2.94286,0.0571429,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.906029;BQB=1;MQ0F=0 PL:DP:DV 0,11,188,24,191,195:9:1 0,15,148,15,148,148:5:0 0,12,132,12,132,132:4:0 +X 3438 . G <*> 0 . DP=18;I16=10,7,0,0,622,23296,0,0,1020,61200,0,0,335,7461,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,215:8:0 0,15,152:5:0 0,12,140:4:0 +X 3439 . A <*> 0 . DP=18;I16=10,8,0,0,619,22965,0,0,1049,62041,0,0,355,7853,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,27,215:9:0 0,15,153:5:0 0,12,132:4:0 +X 3440 . G <*> 0 . DP=18;I16=10,7,0,0,610,22660,0,0,1020,61200,0,0,339,7613,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,15,143:5:0 0,12,131:4:0 +X 3441 . C <*> 0 . DP=18;I16=10,6,0,0,585,22165,0,0,960,57600,0,0,315,7037,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,226:8:0 0,15,140:5:0 0,9,115:3:0 +X 3442 . T <*> 0 . DP=20;I16=11,9,0,0,670,24716,0,0,1138,66482,0,0,362,8166,0,0;QS=3,0;MQSB=0.997118;MQ0F=0 PL:DP:DV 0,33,248:11:0 0,15,143:5:0 0,12,128:4:0 +X 3443 . G <*> 0 . DP=20;I16=11,9,0,0,708,26092,0,0,1138,66482,0,0,366,8288,0,0;QS=3,0;MQSB=0.997118;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,143:5:0 0,12,137:4:0 +X 3444 . A <*> 0 . DP=20;I16=11,9,0,0,698,25978,0,0,1138,66482,0,0,369,8379,0,0;QS=3,0;MQSB=0.997118;MQ0F=0 PL:DP:DV 0,33,244:11:0 0,15,161:5:0 0,12,131:4:0 +X 3445 . G <*> 0 . DP=20;I16=11,9,0,0,718,26590,0,0,1138,66482,0,0,372,8488,0,0;QS=3,0;MQSB=0.997118;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,153:5:0 0,12,132:4:0 +X 3446 . A <*> 0 . DP=20;I16=10,8,0,0,635,23323,0,0,1049,62041,0,0,325,7365,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,27,222:9:0 0,15,154:5:0 0,12,131:4:0 +X 3447 . T <*> 0 . DP=20;I16=11,8,0,0,669,24331,0,0,1109,65641,0,0,352,8084,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,30,230:10:0 0,15,150:5:0 0,12,137:4:0 +X 3448 . C <*> 0 . DP=19;I16=10,8,0,0,641,23693,0,0,1049,62041,0,0,355,8193,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,113:4:0 0,12,128:4:0 +X 3449 . A <*> 0 . DP=19;I16=10,8,0,0,565,19185,0,0,1049,62041,0,0,357,8265,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,30,217:10:0 0,12,111:4:0 0,12,119:4:0 +X 3450 . C <*> 0 . DP=18;I16=8,8,0,0,520,17846,0,0,898,52082,0,0,334,7674,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,229:10:0 0,6,70:2:0 0,12,106:4:0 +X 3451 . G <*> 0 . DP=18;I16=10,7,0,0,528,17178,0,0,989,58441,0,0,361,8345,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,30,226:10:0 0,9,56:3:0 0,12,123:4:0 +X 3452 . C <*> 0 . DP=18;I16=10,8,0,0,657,24597,0,0,1018,59282,0,0,388,9028,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,84:3:0 0,12,128:4:0 +X 3453 . C <*> 0 . DP=18;I16=10,8,0,0,663,24951,0,0,1018,59282,0,0,390,9098,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,90:3:0 0,12,125:4:0 +X 3454 . A <*> 0 . DP=18;I16=10,8,0,0,614,21898,0,0,1018,59282,0,0,392,9180,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,33,251:11:0 0,9,90:3:0 0,12,128:4:0 +X 3455 . C <*> 0 . DP=18;I16=10,8,0,0,650,23968,0,0,1018,59282,0,0,394,9274,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,90:3:0 0,12,127:4:0 +X 3456 . T <*> 0 . DP=18;I16=10,8,0,0,607,21961,0,0,1018,59282,0,0,395,9329,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,33,243:11:0 0,9,88:3:0 0,12,135:4:0 +X 3457 . G <*> 0 . DP=18;I16=9,7,0,0,549,19861,0,0,898,52082,0,0,346,8144,0,0;QS=3,0;MQSB=0.994413;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,6,63:2:0 0,9,107:3:0 +X 3458 . C <*> 0 . DP=18;I16=10,8,0,0,638,23236,0,0,1018,59282,0,0,397,9469,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,81:3:0 0,12,125:4:0 +X 3459 . A C,<*> 0 . DP=17;I16=9,7,0,1,520,18390,22,484,929,54841,29,841,372,8830,25,625;QS=2.92971,0.0702875,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.998843;BQB=1;MQ0F=0 PL:DP:DV 0,8,201,27,204,213:10:1 0,9,84,9,84,84:3:0 0,12,116,12,116,116:4:0 +X 3460 . C <*> 0 . DP=17;I16=8,7,0,0,554,20952,0,0,869,51241,0,0,345,8103,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,6,65:2:0 0,12,131:4:0 +X 3461 . T <*> 0 . DP=17;I16=9,7,0,0,591,22805,0,0,929,54841,0,0,368,8638,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,27,231:9:0 0,9,103:3:0 0,12,133:4:0 +X 3462 . C <*> 0 . DP=18;I16=9,9,0,0,672,25486,0,0,1018,59282,0,0,391,9185,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,90:3:0 0,12,130:4:0 +X 3463 . C <*> 0 . DP=18;I16=8,9,0,0,584,21458,0,0,958,55682,0,0,369,8671,0,0;QS=3,0;MQSB=0.998843;MQ0F=0 PL:DP:DV 0,30,244:10:0 0,9,86:3:0 0,12,132:4:0 +X 3464 . A <*> 0 . DP=18;I16=9,9,0,0,628,23490,0,0,1018,59282,0,0,387,8973,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,244:11:0 0,9,96:3:0 0,12,142:4:0 +X 3465 . G <*> 0 . DP=19;I16=9,9,0,0,642,24008,0,0,1018,59282,0,0,384,8842,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,91:3:0 0,12,135:4:0 +X 3466 . C <*> 0 . DP=20;I16=9,10,0,0,682,25218,0,0,1047,60123,0,0,378,8588,0,0;QS=3,0;MQSB=0.904084;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,101:3:0 0,15,147:5:0 +X 3467 . C <*> 0 . DP=20;I16=10,9,0,0,685,25919,0,0,1047,60123,0,0,397,9139,0,0;QS=3,0;MQSB=0.948064;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,115:4:0 0,15,154:5:0 +X 3468 . T <*> 0 . DP=20;I16=10,9,0,0,672,25426,0,0,1047,60123,0,0,374,8410,0,0;QS=3,0;MQSB=0.948064;MQ0F=0 PL:DP:DV 0,30,246:10:0 0,12,126:4:0 0,15,164:5:0 +X 3469 . G <*> 0 . DP=21;I16=10,11,0,0,788,30064,0,0,1167,67323,0,0,396,8924,0,0;QS=3,0;MQSB=0.914611;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,146:5:0 0,15,163:5:0 +X 3470 . G <*> 0 . DP=22;I16=11,11,0,0,796,29754,0,0,1196,68164,0,0,393,8781,0,0;QS=3,0;MQSB=0.770381;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,131:5:0 0,15,161:5:0 +X 3471 . G <*> 0 . DP=23;I16=12,11,0,0,801,29083,0,0,1256,71764,0,0,391,8657,0,0;QS=3,0;MQSB=0.811552;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,133:5:0 0,15,151:5:0 +X 3472 . C <*> 0 . DP=23;I16=12,11,0,0,757,26535,0,0,1256,71764,0,0,390,8554,0,0;QS=3,0;MQSB=0.811552;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,145:5:0 0,15,136:5:0 +X 3473 . A <*> 0 . DP=23;I16=11,11,0,0,777,28175,0,0,1196,68164,0,0,379,8373,0,0;QS=3,0;MQSB=0.770381;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,148:5:0 0,15,153:5:0 +X 3474 . A <*> 0 . DP=23;I16=12,11,0,0,807,29181,0,0,1256,71764,0,0,388,8414,0,0;QS=3,0;MQSB=0.811552;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,150:5:0 0,15,155:5:0 +X 3475 . C <*> 0 . DP=22;I16=12,10,0,0,737,25849,0,0,1196,68164,0,0,387,8327,0,0;QS=3,0;MQSB=0.838545;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,137:5:0 0,15,143:5:0 +X 3476 . A <*> 0 . DP=22;I16=12,10,0,0,790,29312,0,0,1196,68164,0,0,386,8262,0,0;QS=3,0;MQSB=0.838545;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,149:5:0 0,15,154:5:0 +X 3477 . G <*> 0 . DP=22;I16=11,10,0,0,755,28237,0,0,1136,64564,0,0,363,7735,0,0;QS=3,0;MQSB=0.799507;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,126:4:0 0,15,153:5:0 +X 3478 . A <*> 0 . DP=25;I16=13,11,0,0,857,31637,0,0,1316,75364,0,0,384,8198,0,0;QS=3,0;MQSB=0.845496;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,167:6:0 0,18,190:6:0 +X 3479 . G <*> 0 . DP=25;I16=12,10,0,0,783,28623,0,0,1227,70923,0,0,355,7701,0,0;QS=3,0;MQSB=0.613159;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,152:5:0 0,18,160:6:0 +X 3480 . T <*> 0 . DP=25;I16=13,11,0,0,788,27124,0,0,1316,75364,0,0,393,8531,0,0;QS=3,0;MQSB=0.845496;MQ0F=0 PL:DP:DV 0,33,249:11:0 0,21,182:7:0 0,18,155:6:0 +X 3481 . A <*> 0 . DP=25;I16=12,12,0,0,858,30884,0,0,1347,78123,0,0,397,8685,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,194:7:0 0,15,148:5:0 +X 3482 . A <*> 0 . DP=25;I16=13,12,0,0,927,35013,0,0,1376,78964,0,0,412,8942,0,0;QS=3,0;MQSB=0.822311;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,202:7:0 0,18,182:6:0 +X 3483 . G <*> 0 . DP=25;I16=12,12,0,0,794,27410,0,0,1316,75364,0,0,412,9002,0,0;QS=3,0;MQSB=0.786628;MQ0F=0 PL:DP:DV 0,33,253:11:0 0,21,183:7:0 0,18,158:6:0 +X 3484 . A C,<*> 0 . DP=24;I16=12,9,0,1,710,25220,14,196,1198,70082,60,3600,346,7514,25,625;QS=2.93665,0.0633484,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.804615;BQB=1;MQ0F=0 PL:DP:DV 0,30,227,30,227,227:10:0 0,7,156,18,159,162:7:1 0,15,133,15,133,133:5:0 +X 3485 . C <*> 0 . DP=23;I16=11,11,0,0,766,27656,0,0,1196,68164,0,0,393,8573,0,0;QS=3,0;MQSB=0.770381;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,163:6:0 0,15,120:5:0 +X 3486 . T <*> 0 . DP=24;I16=12,10,0,0,799,30529,0,0,1196,68164,0,0,398,8756,0,0;QS=3,0;MQSB=0.838545;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,198:7:0 0,15,128:5:0 +X 3487 . C <*> 0 . DP=24;I16=10,11,0,0,724,27586,0,0,1167,67323,0,0,393,8905,0,0;QS=3,0;MQSB=0.914611;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,162:6:0 0,12,92:4:0 +X 3488 . T <*> 0 . DP=24;I16=12,10,0,0,742,27454,0,0,1196,68164,0,0,429,9571,0,0;QS=3,0;MQSB=0.838545;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,172:7:0 0,12,98:4:0 +X 3489 . G <*> 0 . DP=25;I16=13,11,0,0,778,28994,0,0,1285,72605,0,0,433,9675,0,0;QS=3,0;MQSB=0.97965;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,177:8:0 0,12,75:4:0 +X 3490 . T C,<*> 0 . DP=27;I16=14,10,1,0,806,28886,25,625,1254,69846,60,3600,427,9659,12,144;QS=2.90775,0.0922509,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.962269;BQB=1;MQ0F=0 PL:DP:DV 0,39,255,39,255,255:13:0 0,2,168,24,171,183:9:1 0,9,85,9,85,85:3:0 +X 3491 . C <*> 0 . DP=28;I16=15,11,0,0,864,31232,0,0,1405,79805,0,0,445,9903,0,0;QS=3,0;MQSB=0.753395;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,197:9:0 0,9,78:3:0 +X 3492 . T <*> 0 . DP=28;I16=15,11,0,0,852,31516,0,0,1405,79805,0,0,452,9986,0,0;QS=3,0;MQSB=0.753395;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,212:9:0 0,9,96:3:0 +X 3493 . C <*> 0 . DP=28;I16=15,12,0,0,891,32181,0,0,1434,80646,0,0,464,10124,0,0;QS=3,0;MQSB=0.908075;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,214:9:0 0,9,80:3:0 +X 3493 . CAAAAAAAAAAAAA CAAAAAAAAAAAA,CAAAAAAAAAAAAAA 0 . INDEL;IDV=2;IMF=0.125;DP=28;I16=9,9,0,2,443,11071,47,1129,1049,62041,89,4441,320,7120,30,650;QS=2.81818,0.0909091,0.0909091;VDB=0.504964;SGB=0.346553;MQSB=0.997118;MQ0F=0 PL:DP:DV 0,19,37,19,40,37:11:2 0,18,39,18,39,39:6:0 0,9,23,9,23,23:3:0 +X 3494 . A <*> 0 . DP=30;I16=15,12,0,0,970,37408,0,0,1465,83405,0,0,440,9568,0,0;QS=3,0;MQSB=0.723173;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,220:9:0 0,12,117:4:0 +X 3495 . A <*> 0 . DP=31;I16=15,13,0,0,966,36178,0,0,1525,87005,0,0,472,10270,0,0;QS=3,0;MQSB=0.695496;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,210:9:0 0,15,129:5:0 +X 3496 . A <*> 0 . DP=31;I16=15,13,0,0,974,36928,0,0,1525,87005,0,0,477,10281,0,0;QS=3,0;MQSB=0.695496;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,207:9:0 0,15,138:5:0 +X 3497 . A <*> 0 . DP=32;I16=14,14,0,0,1015,39525,0,0,1525,87005,0,0,460,9834,0,0;QS=3,0;MQSB=0.62781;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,208:8:0 0,18,148:6:0 +X 3498 . A <*> 0 . DP=32;I16=14,14,0,0,982,37264,0,0,1556,89764,0,0,460,9628,0,0;QS=3,0;MQSB=0.813104;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,220:9:0 0,15,115:5:0 +X 3499 . A <*> 0 . DP=32;I16=14,14,0,0,1024,40072,0,0,1525,87005,0,0,489,10267,0,0;QS=3,0;MQSB=0.62781;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,222:8:0 0,18,144:6:0 +X 3500 . A <*> 0 . DP=31;I16=14,14,0,0,995,38097,0,0,1525,87005,0,0,494,10316,0,0;QS=3,0;MQSB=0.62781;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,214:8:0 0,18,150:6:0 +X 3501 . A <*> 0 . DP=31;I16=14,14,0,0,1017,39845,0,0,1525,87005,0,0,499,10399,0,0;QS=3,0;MQSB=0.62781;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,221:8:0 0,18,149:6:0 +X 3502 . A <*> 0 . DP=31;I16=14,14,0,0,1051,41955,0,0,1525,87005,0,0,504,10516,0,0;QS=3,0;MQSB=0.62781;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,223:8:0 0,18,154:6:0 +X 3503 . A <*> 0 . DP=31;I16=14,14,0,0,1038,40832,0,0,1525,87005,0,0,509,10667,0,0;QS=3,0;MQSB=0.62781;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,229:8:0 0,18,155:6:0 +X 3504 . A <*> 0 . DP=31;I16=14,14,0,0,1037,41235,0,0,1525,87005,0,0,512,10750,0,0;QS=3,0;MQSB=0.62781;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,229:8:0 0,18,145:6:0 +X 3505 . A <*> 0 . DP=31;I16=14,14,0,0,1039,40959,0,0,1525,87005,0,0,514,10814,0,0;QS=3,0;MQSB=0.62781;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,233:8:0 0,18,156:6:0 +X 3506 . A <*> 0 . DP=32;I16=11,13,0,0,889,34265,0,0,1378,80882,0,0,427,9079,0,0;QS=3,0;MQSB=0.998323;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,201:6:0 0,18,158:6:0 +X 3507 . T <*> 0 . DP=31;I16=10,17,0,0,995,38431,0,0,1527,88923,0,0,493,10499,0,0;QS=3,0;MQSB=0.997168;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,187:6:0 0,18,153:6:0 +X 3508 . C <*> 0 . DP=31;I16=10,17,0,0,997,40091,0,0,1527,88923,0,0,499,10675,0,0;QS=3,0;MQSB=0.997168;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,160:6:0 0,15,119:5:0 +X 3509 . A <*> 0 . DP=30;I16=11,17,0,0,995,37147,0,0,1556,89764,0,0,529,11459,0,0;QS=3,0;MQSB=0.960952;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,175:6:0 0,15,125:5:0 +X 3510 . C A,<*> 0 . DP=29;I16=9,17,1,0,959,37997,40,1600,1498,88082,29,841,483,10351,25,625;QS=2.95246,0.047541,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.997168;BQB=1;MQ0F=0 PL:DP:DV 0,19,255,45,255,255:16:1 0,18,150,18,150,150:6:0 0,15,119,15,119,119:5:0 +X 3511 . A <*> 0 . DP=32;I16=11,17,0,0,923,33125,0,0,1587,92523,0,0,512,11150,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,169:6:0 0,15,115:5:0 +X 3512 . C <*> 0 . DP=32;I16=10,18,0,0,1058,42208,0,0,1618,95282,0,0,493,10733,0,0;QS=3,0;MQSB=0.891417;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,181:6:0 0,15,131:5:0 +X 3513 . C A,<*> 0 . DP=32;I16=10,18,1,0,1074,42406,13,169,1618,95282,29,841,498,10926,25,625;QS=2.98,0.02,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.995968;BQB=1;MQ0F=0 PL:DP:DV 0,39,255,51,255,255:18:1 0,18,190,18,190,190:6:0 0,15,136,15,136,136:5:0 +X 3514 . A <*> 0 . DP=33;I16=11,19,0,0,1101,42213,0,0,1707,99723,0,0,528,11778,0,0;QS=3,0;MQSB=0.997918;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,199:7:0 0,15,132:5:0 +X 3515 . T <*> 0 . DP=33;I16=12,19,0,0,1130,43380,0,0,1736,100564,0,0,557,12563,0,0;QS=3,0;MQSB=0.960505;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,192:7:0 0,15,126:5:0 +X 3516 . T <*> 0 . DP=34;I16=14,17,0,0,1147,44331,0,0,1767,103323,0,0,536,12078,0,0;QS=3,0;MQSB=0.924242;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,203:7:0 0,15,133:5:0 +X 3517 . T <*> 0 . DP=34;I16=14,18,0,0,1183,46549,0,0,1796,104164,0,0,565,12773,0,0;QS=3,0;MQSB=0.988522;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,210:7:0 0,15,153:5:0 +X 3518 . T <*> 0 . DP=34;I16=14,18,0,0,1165,44867,0,0,1796,104164,0,0,568,12826,0,0;QS=3,0;MQSB=0.988522;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,203:7:0 0,15,141:5:0 +X 3519 . G <*> 0 . DP=33;I16=13,18,0,0,1158,46678,0,0,1736,100564,0,0,572,12912,0,0;QS=3,0;MQSB=0.980167;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,18,189:6:0 0,15,154:5:0 +X 3520 . G <*> 0 . DP=33;I16=12,18,0,0,1111,42471,0,0,1707,99723,0,0,552,12438,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,183:6:0 0,15,151:5:0 +X 3521 . C <*> 0 . DP=32;I16=11,17,0,0,1077,43755,0,0,1649,98041,0,0,530,11850,0,0;QS=3,0;MQSB=0.967085;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,185:6:0 0,15,143:5:0 +X 3522 . T <*> 0 . DP=32;I16=12,17,0,0,1125,46329,0,0,1678,98882,0,0,552,12274,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,199:6:0 0,15,158:5:0 +X 3523 . T <*> 0 . DP=31;I16=11,16,0,0,996,38204,0,0,1558,91682,0,0,544,12286,0,0;QS=3,0;MQSB=0.992419;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,193:6:0 0,15,145:5:0 +X 3524 . C <*> 0 . DP=31;I16=11,16,0,0,1067,43883,0,0,1589,94441,0,0,538,11960,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,192:6:0 0,15,152:5:0 +X 3525 . A <*> 0 . DP=31;I16=13,16,0,0,1132,46402,0,0,1678,98882,0,0,556,12250,0,0;QS=3,0;MQSB=0.997839;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,200:6:0 0,15,165:5:0 +X 3526 . G <*> 0 . DP=31;I16=12,16,0,0,1090,43912,0,0,1649,98041,0,0,543,12053,0,0;QS=3,0;MQSB=0.96195;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,181:6:0 0,15,147:5:0 +X 3527 . A <*> 0 . DP=31;I16=13,16,0,0,1068,41740,0,0,1678,98882,0,0,560,12334,0,0;QS=3,0;MQSB=0.997839;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,170:6:0 0,15,157:5:0 +X 3528 . T <*> 0 . DP=31;I16=13,16,0,0,1076,41782,0,0,1678,98882,0,0,561,12369,0,0;QS=3,0;MQSB=0.997839;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,193:6:0 0,15,152:5:0 +X 3529 . T <*> 0 . DP=31;I16=12,16,0,0,1016,38674,0,0,1649,98041,0,0,550,12290,0,0;QS=3,0;MQSB=0.96195;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,184:6:0 0,15,154:5:0 +X 3530 . G <*> 0 . DP=30;I16=12,17,0,0,1070,40570,0,0,1709,101641,0,0,578,13032,0,0;QS=3,0;MQSB=0.965321;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,176:6:0 0,18,175:6:0 +X 3531 . C A,<*> 0 . DP=31;I16=13,17,1,0,1080,40304,38,1444,1738,102482,29,841,607,13801,10,100;QS=2.95773,0.0422741,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.924242;BQB=1;MQ0F=0 PL:DP:DV 0,28,255,54,255,255:19:1 0,18,172,18,172,172:6:0 0,18,175,18,175,175:6:0 +X 3532 . A <*> 0 . DP=31;I16=14,17,0,0,1136,42380,0,0,1767,103323,0,0,619,14003,0,0;QS=3,0;MQSB=0.924242;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,180:6:0 0,18,184:6:0 +X 3533 . T <*> 0 . DP=31;I16=13,17,0,0,1074,39206,0,0,1738,102482,0,0,595,13457,0,0;QS=3,0;MQSB=0.996503;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,180:6:0 0,18,176:6:0 +X 3534 . A <*> 0 . DP=30;I16=12,17,0,0,1014,36168,0,0,1678,98882,0,0,597,13561,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,165:6:0 0,18,175:6:0 +X 3535 . T <*> 0 . DP=31;I16=14,17,0,0,1042,36456,0,0,1767,103323,0,0,624,14314,0,0;QS=3,0;MQSB=0.924242;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,162:6:0 0,18,164:6:0 +X 3536 . C <*> 0 . DP=31;I16=13,17,0,0,1102,41182,0,0,1738,102482,0,0,602,13842,0,0;QS=3,0;MQSB=0.996503;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,178:6:0 0,18,180:6:0 +X 3537 . C <*> 0 . DP=32;I16=13,17,0,0,1142,43828,0,0,1769,105241,0,0,598,13854,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,194:7:0 0,18,185:6:0 +X 3538 . T <*> 0 . DP=32;I16=14,17,0,0,1151,43471,0,0,1798,106082,0,0,603,13923,0,0;QS=3,0;MQSB=0.998229;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,211:7:0 0,18,185:6:0 +X 3539 . C <*> 0 . DP=32;I16=12,17,0,0,1077,40959,0,0,1709,101641,0,0,600,13994,0,0;QS=3,0;MQSB=0.965321;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,170:6:0 0,18,173:6:0 +X 3540 . C <*> 0 . DP=31;I16=13,17,0,0,1134,43546,0,0,1769,105241,0,0,603,14055,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,209:7:0 0,18,172:6:0 +X 3541 . T <*> 0 . DP=32;I16=13,18,0,0,1143,42901,0,0,1829,108841,0,0,604,14134,0,0;QS=3,0;MQSB=0.966712;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,224:8:0 0,18,187:6:0 +X 3542 . G <*> 0 . DP=32;I16=13,18,0,0,1152,43714,0,0,1829,108841,0,0,604,14134,0,0;QS=3,0;MQSB=0.966712;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,223:8:0 0,18,172:6:0 +X 3543 . C <*> 0 . DP=31;I16=13,17,0,0,1142,43818,0,0,1769,105241,0,0,605,14153,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,221:8:0 0,18,188:6:0 +X 3544 . A <*> 0 . DP=31;I16=13,17,0,0,1089,40065,0,0,1769,105241,0,0,606,14190,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,221:8:0 0,18,173:6:0 +X 3545 . A <*> 0 . DP=30;I16=13,16,0,0,1118,43688,0,0,1709,101641,0,0,607,14195,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,228:7:0 0,18,196:6:0 +X 3546 . G <*> 0 . DP=30;I16=14,16,0,0,1131,43425,0,0,1738,102482,0,0,630,14698,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,206:7:0 0,18,179:6:0 +X 3547 . G <*> 0 . DP=31;I16=13,17,0,0,1076,39798,0,0,1769,105241,0,0,607,14163,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,189:7:0 0,18,187:6:0 +X 3548 . A <*> 0 . DP=31;I16=13,17,0,0,1071,39059,0,0,1769,105241,0,0,608,14178,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,208:7:0 0,18,179:6:0 +X 3549 . T <*> 0 . DP=30;I16=13,16,0,0,1008,35928,0,0,1678,98882,0,0,605,13989,0,0;QS=3,0;MQSB=0.997839;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,180:6:0 0,15,152:5:0 +X 3550 . A <*> 0 . DP=30;I16=13,16,0,0,1061,39371,0,0,1709,101641,0,0,612,14270,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,194:7:0 0,15,173:5:0 +X 3551 . T <*> 0 . DP=30;I16=13,16,0,0,1026,36844,0,0,1709,101641,0,0,613,14295,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,192:7:0 0,15,162:5:0 +X 3552 . A <*> 0 . DP=30;I16=14,16,0,0,1080,39588,0,0,1738,102482,0,0,631,14627,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,202:7:0 0,15,158:5:0 +X 3553 . T A,<*> 0 . DP=30;I16=13,16,1,0,1047,38333,20,400,1709,101641,29,841,616,14398,16,256;QS=2.96795,0.0320513,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.999136;BQB=1;MQ0F=0 PL:DP:DV 0,34,255,51,255,255:18:1 0,18,178,18,178,178:6:0 0,18,183,18,183,183:6:0 +X 3554 . A <*> 0 . DP=30;I16=14,16,0,0,1063,38413,0,0,1738,102482,0,0,632,14602,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,185:6:0 0,18,179:6:0 +X 3555 . C <*> 0 . DP=30;I16=14,16,0,0,1021,35781,0,0,1738,102482,0,0,632,14574,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,169:6:0 0,18,163:6:0 +X 3556 . G <*> 0 . DP=30;I16=13,16,0,0,1014,36426,0,0,1709,101641,0,0,618,14350,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,168:6:0 0,18,173:6:0 +X 3557 . C <*> 0 . DP=31;I16=14,16,0,0,1001,34919,0,0,1769,105241,0,0,618,14342,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,140:6:0 0,18,165:6:0 +X 3558 . G <*> 0 . DP=31;I16=15,16,0,0,1036,35974,0,0,1798,106082,0,0,630,14476,0,0;QS=3,0;MQSB=0.999805;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,159:6:0 0,18,171:6:0 +X 3559 . T <*> 0 . DP=30;I16=14,16,0,0,1086,40202,0,0,1769,105241,0,0,619,14341,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,171:6:0 0,18,192:6:0 +X 3560 . G <*> 0 . DP=31;I16=14,16,0,0,1151,45035,0,0,1738,102482,0,0,611,14127,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,165:5:0 0,18,194:6:0 +X 3561 . A <*> 0 . DP=31;I16=15,16,0,0,1147,43431,0,0,1798,106082,0,0,626,14366,0,0;QS=3,0;MQSB=0.999805;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,186:6:0 0,18,196:6:0 +X 3562 . A <*> 0 . DP=31;I16=16,15,0,0,1157,43859,0,0,1798,106082,0,0,623,14257,0,0;QS=3,0;MQSB=0.999805;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,192:6:0 0,21,213:7:0 +X 3563 . A <*> 0 . DP=31;I16=16,15,0,0,1162,44010,0,0,1798,106082,0,0,620,14124,0,0;QS=3,0;MQSB=0.999805;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,192:6:0 0,21,216:7:0 +X 3564 . T <*> 0 . DP=31;I16=15,15,0,0,1132,43298,0,0,1769,105241,0,0,610,13932,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,192:6:0 0,21,214:7:0 +X 3565 . T <*> 0 . DP=32;I16=16,16,0,0,1163,42649,0,0,1858,109682,0,0,611,13791,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,189:6:0 0,21,212:7:0 +X 3566 . C <*> 0 . DP=32;I16=16,16,0,0,1162,43586,0,0,1858,109682,0,0,606,13596,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,181:6:0 0,21,209:7:0 +X 3567 . A <*> 0 . DP=32;I16=15,16,0,0,1181,45245,0,0,1829,108841,0,0,597,13375,0,0;QS=3,0;MQSB=0.957006;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,192:6:0 0,21,222:7:0 +X 3568 . A <*> 0 . DP=32;I16=15,16,0,0,1194,46670,0,0,1829,108841,0,0,592,13200,0,0;QS=3,0;MQSB=0.957006;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,204:6:0 0,21,228:7:0 +X 3569 . G <*> 0 . DP=31;I16=15,16,0,0,1164,44544,0,0,1829,108841,0,0,586,13006,0,0;QS=3,0;MQSB=0.957006;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,180:6:0 0,21,204:7:0 +X 3570 . T <*> 0 . DP=30;I16=14,15,0,0,1029,37527,0,0,1709,101641,0,0,572,12730,0,0;QS=3,0;MQSB=0.954405;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,136:4:0 0,21,213:7:0 +X 3571 . C <*> 0 . DP=28;I16=13,15,0,0,1066,41192,0,0,1649,98041,0,0,568,12564,0,0;QS=3,0;MQSB=0.956162;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,138:4:0 0,21,215:7:0 +X 3572 . A <*> 0 . DP=29;I16=13,16,0,0,1108,42566,0,0,1709,101641,0,0,564,12426,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,172:5:0 0,21,218:7:0 +X 3573 . A <*> 0 . DP=29;I16=13,16,0,0,1119,43403,0,0,1709,101641,0,0,558,12168,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,174:5:0 0,21,220:7:0 +X 3574 . T <*> 0 . DP=29;I16=13,16,0,0,1104,42220,0,0,1709,101641,0,0,552,11942,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,175:5:0 0,21,218:7:0 +X 3575 . G <*> 0 . DP=29;I16=13,16,0,0,1122,43748,0,0,1709,101641,0,0,546,11748,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,161:5:0 0,21,212:7:0 +X 3576 . A <*> 0 . DP=29;I16=13,16,0,0,1043,38405,0,0,1709,101641,0,0,540,11586,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,170:5:0 0,21,213:7:0 +X 3577 . C <*> 0 . DP=30;I16=13,17,0,0,1123,42529,0,0,1769,105241,0,0,534,11456,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,161:5:0 0,21,211:7:0 +X 3578 . A <*> 0 . DP=30;I16=13,17,0,0,1148,44236,0,0,1769,105241,0,0,529,11359,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,178:5:0 0,21,216:7:0 +X 3579 . A <*> 0 . DP=29;I16=13,16,0,0,1051,38961,0,0,1709,101641,0,0,524,11244,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,172:5:0 0,18,192:6:0 +X 3580 . A <*> 0 . DP=29;I16=13,16,0,0,1104,42344,0,0,1709,101641,0,0,519,11159,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,172:5:0 0,18,201:6:0 +X 3581 . T <*> 0 . DP=29;I16=13,16,0,0,1088,41226,0,0,1709,101641,0,0,513,11055,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,161:5:0 0,18,199:6:0 +X 3582 . C <*> 0 . DP=29;I16=13,16,0,0,1120,43616,0,0,1709,101641,0,0,506,10934,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,172:5:0 0,18,201:6:0 +X 3583 . A <*> 0 . DP=30;I16=14,16,0,0,1130,43606,0,0,1769,105241,0,0,498,10796,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,183:5:0 0,21,213:7:0 +X 3584 . G <*> 0 . DP=29;I16=12,16,0,0,1027,38895,0,0,1649,98041,0,0,487,10665,0,0;QS=3,0;MQSB=0.96195;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,137:4:0 0,21,209:7:0 +X 3585 . A <*> 0 . DP=31;I16=14,17,0,0,1057,37719,0,0,1829,108841,0,0,486,10616,0,0;QS=3,0;MQSB=0.962133;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,168:5:0 0,24,209:8:0 +X 3586 . A <*> 0 . DP=30;I16=14,15,0,0,1053,40043,0,0,1709,101641,0,0,477,10461,0,0;QS=3,0;MQSB=0.954405;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,174:5:0 0,24,213:8:0 +X 3587 . G A,<*> 0 . DP=29;I16=4,7,10,6,426,16884,555,20381,660,39600,960,57600,192,4420,280,5942;QS=1.32665,1.67335,0;VDB=0.902044;SGB=-3.91326;RPB=0.800999;MQB=1;MQSB=1;BQB=0.156944;MQ0F=0 PL:DP:DV 161,0,184,182,205,255:14:7 22,0,118,34,121,148:5:1 212,24,0,212,24,212:8:8 +X 3588 . A <*> 0 . DP=29;I16=14,14,0,0,999,36973,0,0,1680,100800,0,0,470,10254,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,166:5:0 0,24,215:8:0 +X 3589 . A <*> 0 . DP=28;I16=14,13,0,0,967,35935,0,0,1620,97200,0,0,467,10173,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,166:5:0 0,24,206:8:0 +X 3590 . A <*> 0 . DP=27;I16=13,13,0,0,948,35860,0,0,1560,93600,0,0,464,10072,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,146:4:0 0,24,211:8:0 +X 3591 . A <*> 0 . DP=26;I16=13,13,0,0,913,33539,0,0,1560,93600,0,0,459,9901,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,144:4:0 0,24,212:8:0 +X 3592 . A <*> 0 . DP=26;I16=13,13,0,0,893,32087,0,0,1560,93600,0,0,453,9711,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,143:4:0 0,24,199:8:0 +X 3593 . A <*> 0 . DP=26;I16=13,13,0,0,891,31363,0,0,1560,93600,0,0,447,9553,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,137:4:0 0,24,198:8:0 +X 3594 . C <*> 0 . DP=25;I16=12,12,0,0,910,34868,0,0,1440,86400,0,0,426,9170,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,142:4:0 0,24,216:8:0 +X 3595 . A <*> 0 . DP=24;I16=13,11,0,0,918,35274,0,0,1440,86400,0,0,438,9328,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,143:4:0 0,21,199:7:0 +X 3596 . T <*> 0 . DP=24;I16=13,11,0,0,837,30077,0,0,1440,86400,0,0,434,9258,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,138:4:0 0,21,188:7:0 +X 3597 . A <*> 0 . DP=24;I16=13,11,0,0,893,33549,0,0,1440,86400,0,0,430,9216,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,132:4:0 0,21,204:7:0 +X 3598 . T <*> 0 . DP=23;I16=12,10,0,0,778,28226,0,0,1320,79200,0,0,415,9005,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,140:4:0 0,21,162:7:0 +X 3599 . A <*> 0 . DP=23;I16=13,10,0,0,859,32403,0,0,1380,82800,0,0,425,9105,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,142:4:0 0,21,182:7:0 +X 3600 . T <*> 0 . DP=24;I16=14,10,0,0,872,32086,0,0,1435,85825,0,0,422,9036,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,139:4:0 0,21,183:7:0 +X 3601 . A <*> 0 . DP=24;I16=14,10,0,0,862,31424,0,0,1435,85825,0,0,420,8994,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,132:4:0 0,21,186:7:0 +X 3602 . T <*> 0 . DP=25;I16=15,10,0,0,873,31323,0,0,1495,89425,0,0,418,8980,0,0;QS=3,0;MQSB=0.962269;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,161:5:0 0,21,174:7:0 +X 3603 . A <*> 0 . DP=26;I16=15,11,0,0,907,32447,0,0,1555,93025,0,0,416,8944,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,151:5:0 0,24,216:8:0 +X 3604 . C <*> 0 . DP=27;I16=16,11,0,0,905,31199,0,0,1615,96625,0,0,415,8937,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,147:6:0 0,24,201:8:0 +X 3605 . G <*> 0 . DP=27;I16=15,11,0,0,853,28887,0,0,1555,93025,0,0,393,8477,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,171:6:0 0,21,174:7:0 +X 3606 . C <*> 0 . DP=27;I16=15,12,0,0,982,36756,0,0,1615,96625,0,0,415,8967,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,187:6:0 0,27,231:9:0 +X 3607 . A <*> 0 . DP=26;I16=15,11,0,0,927,33859,0,0,1555,93025,0,0,417,9005,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,183:6:0 0,27,232:9:0 +X 3608 . A <*> 0 . DP=27;I16=14,12,0,0,930,34054,0,0,1555,93025,0,0,394,8450,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,176:6:0 0,24,232:8:0 +X 3609 . A <*> 0 . DP=27;I16=15,12,0,0,955,34701,0,0,1615,96625,0,0,421,9127,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,186:6:0 0,27,238:9:0 +X 3610 . C <*> 0 . DP=27;I16=14,12,0,0,915,33071,0,0,1555,93025,0,0,397,8537,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,172:6:0 0,24,221:8:0 +X 3611 . C <*> 0 . DP=25;I16=13,11,0,0,899,33995,0,0,1435,85825,0,0,398,8502,0,0;QS=3,0;MQSB=0.950498;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,173:6:0 0,24,234:8:0 +X 3612 . A <*> 0 . DP=25;I16=14,11,0,0,957,37723,0,0,1495,89425,0,0,424,9118,0,0;QS=3,0;MQSB=0.955682;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,194:6:0 0,27,251:9:0 +X 3613 . G <*> 0 . DP=26;I16=13,12,0,0,902,33110,0,0,1495,89425,0,0,399,8461,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,172:6:0 0,24,223:8:0 +X 3614 . T <*> 0 . DP=26;I16=14,12,0,0,912,33340,0,0,1555,93025,0,0,425,9083,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,156:6:0 0,27,237:9:0 +X 3615 . A <*> 0 . DP=26;I16=15,11,0,0,946,35138,0,0,1555,93025,0,0,427,9109,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,176:6:0 0,27,242:9:0 +X 3616 . T <*> 0 . DP=26;I16=15,11,0,0,965,36541,0,0,1555,93025,0,0,431,9163,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,185:6:0 0,27,238:9:0 +X 3617 . C <*> 0 . DP=25;I16=14,11,0,0,907,33675,0,0,1495,89425,0,0,436,9196,0,0;QS=3,0;MQSB=0.955682;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,176:6:0 0,24,215:8:0 +X 3618 . C <*> 0 . DP=25;I16=14,11,0,0,964,37698,0,0,1495,89425,0,0,441,9259,0,0;QS=3,0;MQSB=0.955682;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,190:6:0 0,24,225:8:0 +X 3619 . T <*> 0 . DP=25;I16=14,11,0,0,961,37553,0,0,1495,89425,0,0,446,9352,0,0;QS=3,0;MQSB=0.955682;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,194:6:0 0,24,238:8:0 +X 3620 . A <*> 0 . DP=25;I16=14,11,0,0,880,31656,0,0,1495,89425,0,0,451,9475,0,0;QS=3,0;MQSB=0.955682;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,178:6:0 0,24,212:8:0 +X 3621 . C <*> 0 . DP=25;I16=14,11,0,0,949,36561,0,0,1495,89425,0,0,456,9628,0,0;QS=3,0;MQSB=0.955682;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,182:6:0 0,24,230:8:0 +X 3622 . T <*> 0 . DP=26;I16=15,11,0,0,983,38067,0,0,1555,93025,0,0,460,9762,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,194:7:0 0,24,242:8:0 +X 3623 . G <*> 0 . DP=27;I16=16,11,0,0,969,35645,0,0,1615,96625,0,0,465,9929,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,195:7:0 0,24,209:8:0 +X 3624 . T <*> 0 . DP=27;I16=15,11,0,0,948,35330,0,0,1555,93025,0,0,448,9596,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,188:6:0 0,24,224:8:0 +X 3625 . G <*> 0 . DP=27;I16=14,12,0,0,983,37483,0,0,1555,93025,0,0,453,9735,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,210:7:0 0,24,219:8:0 +X 3626 . T <*> 0 . DP=28;I16=15,12,0,0,998,37364,0,0,1615,96625,0,0,458,9854,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,214:7:0 0,27,229:9:0 +X 3627 . G <*> 0 . DP=29;I16=15,13,0,0,999,36375,0,0,1675,100225,0,0,464,10004,0,0;QS=3,0;MQSB=0.956162;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,199:7:0 0,27,224:9:0 +X 3628 . T <*> 0 . DP=29;I16=15,13,0,0,1033,38721,0,0,1675,100225,0,0,471,10187,0,0;QS=3,0;MQSB=0.956162;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,206:7:0 0,27,232:9:0 +X 3629 . G <*> 0 . DP=29;I16=15,13,0,0,1058,40226,0,0,1675,100225,0,0,476,10304,0,0;QS=3,0;MQSB=0.956162;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,207:7:0 0,27,235:9:0 +X 3630 . T <*> 0 . DP=30;I16=15,14,0,0,1052,39072,0,0,1735,103825,0,0,480,10404,0,0;QS=3,0;MQSB=0.954405;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,216:7:0 0,27,223:9:0 +X 3631 . C <*> 0 . DP=29;I16=13,14,0,0,884,29476,0,0,1615,96625,0,0,461,9911,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,186:7:0 0,21,179:7:0 +X 3632 . G <*> 0 . DP=29;I16=14,14,0,0,914,31068,0,0,1675,100225,0,0,491,10649,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,183:7:0 0,24,181:8:0 +X 3633 . T <*> 0 . DP=29;I16=14,14,0,0,1022,38214,0,0,1675,100225,0,0,496,10792,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,216:7:0 0,24,222:8:0 +X 3634 . T <*> 0 . DP=29;I16=14,14,0,0,1043,39891,0,0,1675,100225,0,0,500,10914,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,219:7:0 0,24,227:8:0 +X 3635 . T <*> 0 . DP=28;I16=13,14,0,0,1029,39507,0,0,1615,96625,0,0,505,11063,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,219:7:0 0,24,224:8:0 +X 3636 . G <*> 0 . DP=28;I16=13,14,0,0,1001,37681,0,0,1615,96625,0,0,510,11238,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,201:7:0 0,24,217:8:0 +X 3637 . T <*> 0 . DP=27;I16=13,14,0,0,1019,39331,0,0,1615,96625,0,0,515,11439,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,212:7:0 0,24,240:8:0 +X 3638 . T <*> 0 . DP=26;I16=12,14,0,0,967,36467,0,0,1555,93025,0,0,520,11616,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,185:6:0 0,24,222:8:0 +X 3639 . G <*> 0 . DP=27;I16=13,14,0,0,997,37265,0,0,1615,96625,0,0,524,11768,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,183:6:0 0,27,221:9:0 +X 3640 . T <*> 0 . DP=27;I16=13,14,0,0,1001,37533,0,0,1615,96625,0,0,527,11847,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,191:6:0 0,27,229:9:0 +X 3641 . G <*> 0 . DP=27;I16=13,14,0,0,977,36379,0,0,1615,96625,0,0,529,11905,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,178:6:0 0,27,224:9:0 +X 3642 . T <*> 0 . DP=26;I16=12,13,0,0,931,35169,0,0,1495,89425,0,0,506,11314,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,169:5:0 0,24,225:8:0 +X 3643 . T <*> 0 . DP=26;I16=13,13,0,0,968,36820,0,0,1555,93025,0,0,533,11997,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,176:5:0 0,27,230:9:0 +X 3644 . T <*> 0 . DP=26;I16=12,13,0,0,961,37477,0,0,1495,89425,0,0,517,11755,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,175:5:0 0,24,236:8:0 +X 3645 . T <*> 0 . DP=26;I16=13,13,0,0,980,37508,0,0,1555,93025,0,0,537,12185,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,175:5:0 0,27,239:9:0 +X 3646 . C <*> 0 . DP=26;I16=12,13,0,0,766,25026,0,0,1495,89425,0,0,514,11690,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,33,234:11:0 0,15,136:5:0 0,27,188:9:0 +X 3647 . G <*> 0 . DP=26;I16=12,12,0,0,820,29600,0,0,1435,85825,0,0,492,11218,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,151:5:0 0,21,173:7:0 +X 3648 . A <*> 0 . DP=26;I16=13,12,0,0,924,34680,0,0,1495,89425,0,0,519,11919,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,174:5:0 0,24,225:8:0 +X 3649 . C <*> 0 . DP=26;I16=14,12,0,0,955,36105,0,0,1555,93025,0,0,545,12593,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,173:5:0 0,27,226:9:0 +X 3650 . A <*> 0 . DP=27;I16=15,12,0,0,1033,40511,0,0,1615,96625,0,0,546,12664,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,196:6:0 0,27,246:9:0 +X 3651 . G <*> 0 . DP=27;I16=15,12,0,0,1035,40351,0,0,1615,96625,0,0,547,12707,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,194:6:0 0,27,233:9:0 +X 3652 . C <*> 0 . DP=29;I16=15,13,0,0,1010,38264,0,0,1675,100225,0,0,521,12047,0,0;QS=3,0;MQSB=0.956162;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,198:6:0 0,27,225:9:0 +X 3653 . T <*> 0 . DP=29;I16=16,13,0,0,1109,42919,0,0,1735,103825,0,0,546,12610,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,202:6:0 0,27,239:9:0 +X 3654 . G <*> 0 . DP=28;I16=14,12,0,0,981,37447,0,0,1555,93025,0,0,514,11882,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,184:6:0 0,18,180:6:0 +X 3655 . T <*> 0 . DP=28;I16=16,12,0,0,999,37029,0,0,1675,100225,0,0,541,12505,0,0;QS=3,0;MQSB=0.96195;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,190:6:0 0,21,179:7:0 +X 3656 . C <*> 0 . DP=28;I16=15,12,0,0,963,35883,0,0,1615,96625,0,0,518,11848,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,164:5:0 0,21,191:7:0 +X 3657 . C <*> 0 . DP=28;I16=15,12,0,0,923,32223,0,0,1615,96625,0,0,520,11836,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,154:5:0 0,21,192:7:0 +X 3658 . G <*> 0 . DP=28;I16=15,12,0,0,876,29960,0,0,1615,96625,0,0,539,12405,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,142:5:0 0,21,163:7:0 +X 3659 . T <*> 0 . DP=28;I16=16,12,0,0,996,36682,0,0,1675,100225,0,0,548,12448,0,0;QS=3,0;MQSB=0.96195;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,163:6:0 0,21,186:7:0 +X 3660 . G <*> 0 . DP=28;I16=15,12,0,0,997,37571,0,0,1615,96625,0,0,526,11920,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,172:6:0 0,18,171:6:0 +X 3661 . T <*> 0 . DP=28;I16=16,12,0,0,1013,37837,0,0,1675,100225,0,0,549,12423,0,0;QS=3,0;MQSB=0.96195;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,180:6:0 0,21,188:7:0 +X 3662 . T <*> 0 . DP=28;I16=15,12,0,0,987,36627,0,0,1615,96625,0,0,528,11980,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,182:6:0 0,18,184:6:0 +X 3663 . A <*> 0 . DP=29;I16=16,12,0,0,997,36233,0,0,1675,100225,0,0,527,11959,0,0;QS=3,0;MQSB=0.96195;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,170:6:0 0,18,180:6:0 +X 3664 . T <*> 0 . DP=29;I16=17,12,0,0,1044,38402,0,0,1735,103825,0,0,550,12490,0,0;QS=3,0;MQSB=0.965321;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,183:6:0 0,21,196:7:0 +X 3665 . A <*> 0 . DP=27;I16=16,11,0,0,1017,38535,0,0,1615,96625,0,0,552,12510,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,182:6:0 0,21,208:7:0 +X 3666 . A <*> 0 . DP=27;I16=16,11,0,0,1036,40292,0,0,1615,96625,0,0,554,12550,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,193:6:0 0,21,208:7:0 +X 3667 . T <*> 0 . DP=27;I16=15,11,0,0,955,35895,0,0,1555,93025,0,0,540,12354,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,189:6:0 0,18,189:6:0 +X 3668 . A <*> 0 . DP=27;I16=16,11,0,0,981,36297,0,0,1615,96625,0,0,557,12641,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,182:6:0 0,21,209:7:0 +X 3669 . A <*> 0 . DP=27;I16=16,11,0,0,1030,39666,0,0,1615,96625,0,0,558,12694,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,194:6:0 0,21,209:7:0 +X 3670 . T <*> 0 . DP=28;I16=17,11,0,0,1057,40245,0,0,1675,100225,0,0,559,12769,0,0;QS=3,0;MQSB=0.967085;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,181:6:0 0,24,220:8:0 +X 3671 . T <*> 0 . DP=28;I16=17,11,0,0,1059,40427,0,0,1675,100225,0,0,561,12867,0,0;QS=3,0;MQSB=0.967085;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,193:6:0 0,24,223:8:0 +X 3672 . C <*> 0 . DP=28;I16=16,11,0,0,988,37264,0,0,1615,96625,0,0,550,12820,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,169:6:0 0,21,205:7:0 +X 3673 . C <*> 0 . DP=27;I16=16,10,0,0,1016,40148,0,0,1555,93025,0,0,528,12314,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,154:5:0 0,24,219:8:0 +X 3674 . T <*> 0 . DP=27;I16=17,10,0,0,1035,40645,0,0,1615,96625,0,0,556,13028,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,155:5:0 0,24,228:8:0 +X 3675 . C <*> 0 . DP=27;I16=17,10,0,0,1049,41413,0,0,1615,96625,0,0,558,13090,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,149:5:0 0,24,222:8:0 +X 3676 . T <*> 0 . DP=27;I16=17,10,0,0,1040,40640,0,0,1615,96625,0,0,559,13125,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,159:5:0 0,24,231:8:0 +X 3677 . A <*> 0 . DP=27;I16=16,10,0,0,922,34182,0,0,1555,93025,0,0,537,12557,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,136:5:0 0,24,217:8:0 +X 3678 . G <*> 0 . DP=27;I16=17,10,0,0,1009,38307,0,0,1615,96625,0,0,563,13159,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,149:5:0 0,24,216:8:0 +X 3679 . T <*> 0 . DP=27;I16=17,10,0,0,1018,39274,0,0,1615,96625,0,0,563,13105,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,156:5:0 0,24,227:8:0 +X 3680 . T <*> 0 . DP=27;I16=17,10,0,0,988,36872,0,0,1615,96625,0,0,562,13022,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,157:5:0 0,24,202:8:0 +X 3681 . C <*> 0 . DP=27;I16=17,10,0,0,1012,39154,0,0,1615,96625,0,0,560,12910,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,157:5:0 0,24,217:8:0 +X 3682 . A <*> 0 . DP=27;I16=17,10,0,0,1009,38221,0,0,1615,96625,0,0,557,12769,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,156:5:0 0,24,220:8:0 +X 3683 . A <*> 0 . DP=27;I16=17,9,0,0,966,36748,0,0,1555,93025,0,0,546,12552,0,0;QS=3,0;MQSB=0.971017;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,153:5:0 0,24,225:8:0 +X 3684 . A <*> 0 . DP=26;I16=16,10,0,0,974,37440,0,0,1555,93025,0,0,550,12456,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,155:5:0 0,21,215:7:0 +X 3685 . T <*> 0 . DP=26;I16=16,10,0,0,954,36330,0,0,1555,93025,0,0,547,12333,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,148:5:0 0,21,207:7:0 +X 3686 . T <*> 0 . DP=26;I16=16,10,0,0,979,37645,0,0,1555,93025,0,0,544,12232,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,162:5:0 0,21,216:7:0 +X 3687 . T <*> 0 . DP=27;I16=16,11,0,0,1028,39276,0,0,1592,94394,0,0,541,12153,0,0;QS=3,0;MQSB=0.989102;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,159:5:0 0,24,229:8:0 +X 3688 . A <*> 0 . DP=28;I16=17,10,0,0,1007,37883,0,0,1569,92163,0,0,526,11904,0,0;QS=3,0;MQSB=0.99874;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,148:5:0 0,24,232:8:0 +X 3689 . T <*> 0 . DP=28;I16=17,11,0,0,1042,39780,0,0,1629,95763,0,0,535,11919,0,0;QS=3,0;MQSB=0.995584;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,162:5:0 0,24,233:8:0 +X 3690 . T <*> 0 . DP=28;I16=17,11,0,0,1051,39981,0,0,1629,95763,0,0,532,11816,0,0;QS=3,0;MQSB=0.995584;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,160:5:0 0,24,225:8:0 +X 3691 . C <*> 0 . DP=28;I16=16,11,0,0,1037,40549,0,0,1569,92163,0,0,520,11592,0,0;QS=3,0;MQSB=0.992419;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,155:5:0 0,21,214:7:0 +X 3692 . A <*> 0 . DP=29;I16=18,11,0,0,1028,37574,0,0,1689,99363,0,0,522,11496,0,0;QS=3,0;MQSB=0.99773;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,156:5:0 0,24,209:8:0 +X 3693 . T <*> 0 . DP=28;I16=18,10,0,0,1067,40901,0,0,1629,95763,0,0,519,11381,0,0;QS=3,0;MQSB=0.999713;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,160:5:0 0,24,230:8:0 +X 3694 . T <*> 0 . DP=28;I16=18,10,0,0,1043,39659,0,0,1629,95763,0,0,516,11296,0,0;QS=3,0;MQSB=0.999713;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,159:5:0 0,24,234:8:0 +X 3695 . T <*> 0 . DP=28;I16=18,10,0,0,1046,39662,0,0,1629,95763,0,0,513,11241,0,0;QS=3,0;MQSB=0.999713;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,156:5:0 0,24,233:8:0 +X 3696 . T <*> 0 . DP=28;I16=18,10,0,0,1075,41567,0,0,1629,95763,0,0,509,11165,0,0;QS=3,0;MQSB=0.999713;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,162:5:0 0,24,235:8:0 +X 3697 . T <*> 0 . DP=28;I16=18,10,0,0,1031,38399,0,0,1629,95763,0,0,505,11117,0,0;QS=3,0;MQSB=0.999713;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,155:5:0 0,24,229:8:0 +X 3698 . A <*> 0 . DP=28;I16=18,9,0,0,983,36457,0,0,1569,92163,0,0,477,10515,0,0;QS=3,0;MQSB=0.999669;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,144:5:0 0,24,229:8:0 +X 3699 . A <*> 0 . DP=27;I16=17,10,0,0,1011,38455,0,0,1569,92163,0,0,493,10861,0,0;QS=3,0;MQSB=0.99874;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,150:5:0 0,21,226:7:0 +X 3700 . C <*> 0 . DP=28;I16=16,11,0,0,970,35910,0,0,1574,92738,0,0,473,10525,0,0;QS=3,0;MQSB=0.992419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,168:6:0 0,24,212:8:0 +X 3701 . T <*> 0 . DP=28;I16=17,11,0,0,1071,41669,0,0,1634,96338,0,0,484,10618,0,0;QS=3,0;MQSB=0.990092;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,196:6:0 0,24,233:8:0 +X 3702 . T <*> 0 . DP=28;I16=17,10,0,0,1019,38653,0,0,1597,94969,0,0,462,10144,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,184:6:0 0,21,207:7:0 +X 3703 . C <*> 0 . DP=28;I16=17,11,0,0,1059,40561,0,0,1634,96338,0,0,470,10154,0,0;QS=3,0;MQSB=0.990092;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,183:6:0 0,24,232:8:0 +X 3704 . A <*> 0 . DP=28;I16=17,10,0,0,1015,38483,0,0,1574,92738,0,0,439,9347,0,0;QS=3,0;MQSB=0.984677;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,182:6:0 0,21,211:7:0 +X 3705 . T <*> 0 . DP=27;I16=17,10,0,0,992,37112,0,0,1574,92738,0,0,459,9773,0,0;QS=3,0;MQSB=0.984677;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,180:6:0 0,21,209:7:0 +X 3706 . A <*> 0 . DP=27;I16=17,10,0,0,1040,40262,0,0,1574,92738,0,0,454,9608,0,0;QS=3,0;MQSB=0.984677;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,186:6:0 0,21,204:7:0 +X 3707 . G <*> 0 . DP=26;I16=17,9,0,0,974,37394,0,0,1514,89138,0,0,450,9476,0,0;QS=3,0;MQSB=0.977029;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,173:6:0 0,18,168:6:0 +X 3708 . T <*> 0 . DP=26;I16=18,7,0,0,911,33609,0,0,1454,85538,0,0,426,8934,0,0;QS=3,0;MQSB=0.914166;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,182:6:0 0,15,139:5:0 +X 3709 . A <*> 0 . DP=26;I16=18,8,0,0,905,32473,0,0,1491,86907,0,0,445,9305,0,0;QS=3,0;MQSB=0.998458;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,168:6:0 0,18,162:6:0 +X 3710 . C <*> 0 . DP=26;I16=18,8,0,0,924,33504,0,0,1491,86907,0,0,443,9267,0,0;QS=3,0;MQSB=0.998458;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,165:6:0 0,18,159:6:0 +X 3711 . C <*> 0 . DP=26;I16=18,8,0,0,953,35965,0,0,1491,86907,0,0,441,9261,0,0;QS=3,0;MQSB=0.998458;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,164:6:0 0,18,173:6:0 +X 3712 . A <*> 0 . DP=26;I16=18,8,0,0,893,31917,0,0,1491,86907,0,0,439,9287,0,0;QS=3,0;MQSB=0.998458;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,144:6:0 0,18,165:6:0 +X 3713 . C <*> 0 . DP=26;I16=19,7,0,0,908,32834,0,0,1491,86907,0,0,437,9293,0,0;QS=3,0;MQSB=0.989612;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,163:6:0 0,18,164:6:0 +X 3714 . A <*> 0 . DP=27;I16=19,6,0,0,920,34366,0,0,1408,81076,0,0,409,8651,0,0;QS=3,0;MQSB=0.999494;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,177:6:0 0,18,174:6:0 +X 3715 . T <*> 0 . DP=28;I16=21,6,0,0,982,36286,0,0,1505,86045,0,0,408,8616,0,0;QS=3,0;MQSB=0.996181;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,180:6:0 0,18,164:6:0 +X 3716 . T <*> 0 . DP=26;I16=19,7,0,0,927,33833,0,0,1445,82445,0,0,434,9236,0,0;QS=3,0;MQSB=0.966731;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,165:5:0 0,18,164:6:0 +X 3717 . C <*> 0 . DP=26;I16=19,7,0,0,979,37527,0,0,1445,82445,0,0,435,9261,0,0;QS=3,0;MQSB=0.966731;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,165:5:0 0,18,168:6:0 +X 3718 . T <*> 0 . DP=26;I16=19,7,0,0,994,39040,0,0,1445,82445,0,0,435,9265,0,0;QS=3,0;MQSB=0.966731;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,169:5:0 0,18,165:6:0 +X 3719 . A <*> 0 . DP=26;I16=19,6,0,0,889,32163,0,0,1408,81076,0,0,410,8672,0,0;QS=3,0;MQSB=0.747144;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,148:5:0 0,15,142:5:0 +X 3720 . C <*> 0 . DP=26;I16=19,7,0,0,934,34326,0,0,1445,82445,0,0,435,9357,0,0;QS=3,0;MQSB=0.966731;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,148:5:0 0,18,158:6:0 +X 3721 . A <*> 0 . DP=27;I16=20,5,0,0,910,33944,0,0,1405,80725,0,0,385,8195,0,0;QS=3,0;MQSB=0.697274;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,153:5:0 0,15,145:5:0 +X 3722 . C <*> 0 . DP=27;I16=20,7,0,0,964,35276,0,0,1502,85694,0,0,436,9562,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,151:5:0 0,18,165:6:0 +X 3723 . A <*> 0 . DP=25;I16=18,6,0,0,888,33516,0,0,1345,77125,0,0,414,9082,0,0;QS=3,0;MQSB=0.606531;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,134:4:0 0,15,145:5:0 +X 3724 . C <*> 0 . DP=25;I16=18,7,0,0,944,35956,0,0,1382,78494,0,0,442,9878,0,0;QS=3,0;MQSB=0.889393;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,137:4:0 0,18,169:6:0 +X 3725 . T <*> 0 . DP=25;I16=18,7,0,0,973,38263,0,0,1382,78494,0,0,445,10075,0,0;QS=3,0;MQSB=0.889393;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,138:4:0 0,18,190:6:0 +X 3726 . G <*> 0 . DP=24;I16=18,6,0,0,865,32339,0,0,1322,74894,0,0,446,10146,0,0;QS=3,0;MQSB=0.934987;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,93:3:0 0,18,166:6:0 +X 3727 . C <*> 0 . DP=22;I16=17,5,0,0,762,27812,0,0,1202,67694,0,0,447,10139,0,0;QS=3,0;MQSB=0.963102;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,82:3:0 0,15,143:5:0 +X 3728 . C <*> 0 . DP=22;I16=17,5,0,0,792,29850,0,0,1202,67694,0,0,448,10154,0,0;QS=3,0;MQSB=0.963102;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,89:3:0 0,15,160:5:0 +X 3729 . C <*> 0 . DP=22;I16=17,5,0,0,838,32312,0,0,1202,67694,0,0,449,10191,0,0;QS=3,0;MQSB=0.963102;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,93:3:0 0,15,164:5:0 +X 3730 . A <*> 0 . DP=21;I16=17,4,0,0,749,27561,0,0,1142,64094,0,0,448,10100,0,0;QS=3,0;MQSB=0.995997;MQ0F=0 PL:DP:DV 0,39,241:13:0 0,9,98:3:0 0,15,159:5:0 +X 3731 . T <*> 0 . DP=22;I16=18,4,0,0,787,29489,0,0,1152,64194,0,0,447,10031,0,0;QS=3,0;MQSB=0.967917;MQ0F=0 PL:DP:DV 0,42,253:14:0 0,9,101:3:0 0,15,139:5:0 +X 3732 . G <*> 0 . DP=22;I16=18,4,0,0,811,30695,0,0,1152,64194,0,0,447,9985,0,0;QS=3,0;MQSB=0.967917;MQ0F=0 PL:DP:DV 0,42,252:14:0 0,9,101:3:0 0,15,149:5:0 +X 3733 . T <*> 0 . DP=23;I16=19,4,0,0,820,29616,0,0,1212,67794,0,0,447,9963,0,0;QS=3,0;MQSB=0.979651;MQ0F=0 PL:DP:DV 0,45,248:15:0 0,9,101:3:0 0,15,152:5:0 +X 3734 . C <*> 0 . DP=24;I16=20,4,0,0,863,32277,0,0,1272,71394,0,0,447,9915,0,0;QS=3,0;MQSB=0.988072;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,86:3:0 0,15,152:5:0 +X 3735 . C <*> 0 . DP=24;I16=20,4,0,0,826,30112,0,0,1272,71394,0,0,448,9892,0,0;QS=3,0;MQSB=0.988072;MQ0F=0 PL:DP:DV 0,48,254:16:0 0,9,83:3:0 0,15,152:5:0 +X 3736 . C <*> 0 . DP=25;I16=20,3,0,0,839,31471,0,0,1262,71294,0,0,419,9245,0,0;QS=3,0;MQSB=0.963194;MQ0F=0 PL:DP:DV 0,42,235:14:0 0,9,99:3:0 0,18,156:6:0 +X 3737 . C <*> 0 . DP=25;I16=21,4,0,0,894,33402,0,0,1332,74994,0,0,451,9925,0,0;QS=3,0;MQSB=0.993838;MQ0F=0 PL:DP:DV 0,48,251:16:0 0,9,95:3:0 0,18,175:6:0 +X 3738 . T <*> 0 . DP=25;I16=21,4,0,0,926,35484,0,0,1332,74994,0,0,452,9934,0,0;QS=3,0;MQSB=0.993838;MQ0F=0 PL:DP:DV 0,48,253:16:0 0,9,101:3:0 0,18,189:6:0 +X 3739 . C <*> 0 . DP=25;I16=21,4,0,0,958,37390,0,0,1332,74994,0,0,452,9922,0,0;QS=3,0;MQSB=0.993838;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,105:3:0 0,18,181:6:0 +X 3740 . A <*> 0 . DP=24;I16=20,4,0,0,848,31126,0,0,1272,71394,0,0,452,9886,0,0;QS=3,0;MQSB=0.988072;MQ0F=0 PL:DP:DV 0,48,247:16:0 0,9,109:3:0 0,15,163:5:0 +X 3741 . A <*> 0 . DP=24;I16=19,4,0,0,814,30176,0,0,1212,67794,0,0,442,9742,0,0;QS=3,0;MQSB=0.979651;MQ0F=0 PL:DP:DV 0,48,238:16:0 0,6,82:2:0 0,15,172:5:0 +X 3742 . G <*> 0 . DP=24;I16=20,4,0,0,893,34371,0,0,1272,71394,0,0,450,9782,0,0;QS=3,0;MQSB=0.988072;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,101:3:0 0,15,162:5:0 +X 3743 . C <*> 0 . DP=24;I16=19,4,0,0,839,31673,0,0,1262,71294,0,0,437,9619,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,254:15:0 0,9,103:3:0 0,15,158:5:0 +X 3744 . T <*> 0 . DP=24;I16=20,4,0,0,918,36126,0,0,1272,71394,0,0,448,9766,0,0;QS=3,0;MQSB=0.988072;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,118:3:0 0,15,164:5:0 +X 3745 . T <*> 0 . DP=24;I16=19,4,0,0,808,29490,0,0,1212,67794,0,0,422,9166,0,0;QS=3,0;MQSB=0.979651;MQ0F=0 PL:DP:DV 0,45,233:15:0 0,9,108:3:0 0,15,158:5:0 +X 3746 . C <*> 0 . DP=24;I16=20,4,0,0,886,33564,0,0,1272,71394,0,0,445,9789,0,0;QS=3,0;MQSB=0.988072;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,101:3:0 0,15,165:5:0 +X 3747 . C <*> 0 . DP=24;I16=19,4,0,0,833,31071,0,0,1262,71294,0,0,426,9504,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,249:15:0 0,9,103:3:0 0,15,162:5:0 +X 3748 . C <*> 0 . DP=24;I16=19,4,0,0,845,31753,0,0,1262,71294,0,0,422,9464,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,106:3:0 0,15,161:5:0 +X 3749 . C <*> 0 . DP=24;I16=19,4,0,0,844,31888,0,0,1262,71294,0,0,417,9395,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,250:15:0 0,9,111:3:0 0,15,154:5:0 +X 3750 . T <*> 0 . DP=25;I16=21,4,0,0,876,32880,0,0,1309,72763,0,0,431,9709,0,0;QS=3,0;MQSB=0.966906;MQ0F=0 PL:DP:DV 0,51,251:17:0 0,9,112:3:0 0,15,146:5:0 +X 3751 . G <*> 0 . DP=24;I16=19,4,0,0,836,31374,0,0,1239,69063,0,0,408,9274,0,0;QS=3,0;MQSB=0.986928;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,82:2:0 0,15,162:5:0 +X 3752 . G <*> 0 . DP=22;I16=19,2,0,0,728,26270,0,0,1069,58363,0,0,404,9134,0,0;QS=3,0;MQSB=0.868421;MQ0F=0 PL:DP:DV 0,42,182:14:0 0,6,74:2:0 0,15,159:5:0 +X 3753 . C <*> 0 . DP=22;I16=19,3,0,0,761,28017,0,0,1129,61963,0,0,426,9674,0,0;QS=3,0;MQSB=0.995434;MQ0F=0 PL:DP:DV 0,45,213:15:0 0,6,61:2:0 0,15,163:5:0 +X 3754 . T <*> 0 . DP=23;I16=19,3,0,0,767,28751,0,0,1129,61963,0,0,425,9707,0,0;QS=3,0;MQSB=0.995434;MQ0F=0 PL:DP:DV 0,45,218:15:0 0,6,69:2:0 0,15,157:5:0 +X 3755 . C <*> 0 . DP=21;I16=16,4,0,0,749,28747,0,0,1028,55504,0,0,404,9188,0,0;QS=3,0;MQSB=0.777932;MQ0F=0 PL:DP:DV 0,36,219:12:0 0,9,93:3:0 0,15,161:5:0 +X 3756 . C <*> 0 . DP=22;I16=17,4,0,0,782,29994,0,0,1038,55604,0,0,430,9840,0,0;QS=3,0;MQSB=0.885747;MQ0F=0 PL:DP:DV 0,39,229:13:0 0,9,93:3:0 0,15,159:5:0 +X 3757 . T <*> 0 . DP=23;I16=17,6,0,0,828,30942,0,0,1158,62804,0,0,456,10510,0,0;QS=3,0;MQSB=0.9945;MQ0F=0 PL:DP:DV 0,39,210:13:0 0,15,143:5:0 0,15,169:5:0 +X 3758 . G <*> 0 . DP=23;I16=17,6,0,0,832,30792,0,0,1158,62804,0,0,458,10574,0,0;QS=3,0;MQSB=0.9945;MQ0F=0 PL:DP:DV 0,39,220:13:0 0,15,135:5:0 0,15,147:5:0 +X 3759 . C <*> 0 . DP=23;I16=17,4,0,0,756,28338,0,0,1061,57835,0,0,409,9357,0,0;QS=3,0;MQSB=0.964547;MQ0F=0 PL:DP:DV 0,39,220:13:0 0,12,112:4:0 0,12,127:4:0 +X 3760 . A <*> 0 . DP=24;I16=17,7,0,0,792,27956,0,0,1218,66404,0,0,459,10607,0,0;QS=3,0;MQSB=0.95083;MQ0F=0 PL:DP:DV 0,39,203:13:0 0,15,127:5:0 0,18,180:6:0 +X 3761 . A <*> 0 . DP=24;I16=17,7,0,0,871,32185,0,0,1218,66404,0,0,460,10624,0,0;QS=3,0;MQSB=0.95083;MQ0F=0 PL:DP:DV 0,39,215:13:0 0,15,136:5:0 0,18,188:6:0 +X 3762 . C <*> 0 . DP=25;I16=17,7,0,0,831,29665,0,0,1241,68635,0,0,435,9983,0,0;QS=3,0;MQSB=0.69242;MQ0F=0 PL:DP:DV 0,39,209:13:0 0,18,149:6:0 0,15,159:5:0 +X 3763 . C <*> 0 . DP=24;I16=16,8,0,0,837,30619,0,0,1218,66404,0,0,460,10510,0,0;QS=3,0;MQSB=0.844324;MQ0F=0 PL:DP:DV 0,36,213:12:0 0,18,149:6:0 0,18,186:6:0 +X 3764 . A <*> 0 . DP=25;I16=17,7,0,0,856,31506,0,0,1241,68635,0,0,437,9903,0,0;QS=3,0;MQSB=0.69242;MQ0F=0 PL:DP:DV 0,39,212:13:0 0,18,139:6:0 0,15,167:5:0 +X 3765 . C <*> 0 . DP=25;I16=17,7,0,0,845,31099,0,0,1218,66404,0,0,436,9750,0,0;QS=3,0;MQSB=0.95083;MQ0F=0 PL:DP:DV 0,39,200:13:0 0,15,129:5:0 0,18,189:6:0 +X 3766 . A <*> 0 . DP=26;I16=17,9,0,0,953,35331,0,0,1338,73604,0,0,462,10340,0,0;QS=3,0;MQSB=0.811273;MQ0F=0 PL:DP:DV 0,42,248:14:0 0,18,158:6:0 0,18,191:6:0 +X 3767 . A <*> 0 . DP=26;I16=17,9,0,0,924,33656,0,0,1338,73604,0,0,464,10328,0,0;QS=3,0;MQSB=0.811273;MQ0F=0 PL:DP:DV 0,42,246:14:0 0,18,148:6:0 0,18,191:6:0 +X 3768 . A <*> 0 . DP=26;I16=17,9,0,0,922,33842,0,0,1338,73604,0,0,466,10340,0,0;QS=3,0;MQSB=0.811273;MQ0F=0 PL:DP:DV 0,42,237:14:0 0,18,146:6:0 0,18,195:6:0 +X 3769 . T <*> 0 . DP=26;I16=17,8,0,0,891,32735,0,0,1278,70004,0,0,461,10327,0,0;QS=3,0;MQSB=0.884621;MQ0F=0 PL:DP:DV 0,42,246:14:0 0,15,144:5:0 0,18,191:6:0 +X 3770 . C <*> 0 . DP=26;I16=17,9,0,0,923,34049,0,0,1338,73604,0,0,470,10436,0,0;QS=3,0;MQSB=0.811273;MQ0F=0 PL:DP:DV 0,42,252:14:0 0,18,142:6:0 0,18,180:6:0 +X 3771 . T <*> 0 . DP=25;I16=16,8,0,0,852,31694,0,0,1218,66404,0,0,464,10438,0,0;QS=3,0;MQSB=0.844324;MQ0F=0 PL:DP:DV 0,42,253:14:0 0,15,140:5:0 0,15,157:5:0 +X 3772 . A <*> 0 . DP=26;I16=16,10,0,0,836,28434,0,0,1338,73604,0,0,476,10624,0,0;QS=3,0;MQSB=0.685145;MQ0F=0 PL:DP:DV 0,42,236:14:0 0,18,122:6:0 0,18,160:6:0 +X 3773 . C <*> 0 . DP=26;I16=16,10,0,0,893,31801,0,0,1338,73604,0,0,480,10752,0,0;QS=3,0;MQSB=0.685145;MQ0F=0 PL:DP:DV 0,42,253:14:0 0,18,140:6:0 0,18,171:6:0 +X 3774 . T <*> 0 . DP=25;I16=15,10,0,0,895,33455,0,0,1278,70004,0,0,485,10903,0,0;QS=3,0;MQSB=0.624282;MQ0F=0 PL:DP:DV 0,42,253:14:0 0,18,129:6:0 0,15,178:5:0 +X 3775 . C <*> 0 . DP=25;I16=15,9,0,0,855,31825,0,0,1241,68635,0,0,477,10883,0,0;QS=3,0;MQSB=0.439649;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,147:6:0 0,12,143:4:0 +X 3776 . T <*> 0 . DP=24;I16=15,7,0,0,838,32738,0,0,1152,64194,0,0,457,10375,0,0;QS=3,0;MQSB=0.225079;MQ0F=0 PL:DP:DV 0,39,229:13:0 0,15,149:5:0 0,12,152:4:0 +X 3777 . C <*> 0 . DP=24;I16=15,9,0,0,864,32180,0,0,1218,66404,0,0,492,10998,0,0;QS=3,0;MQSB=0.705785;MQ0F=0 PL:DP:DV 0,39,220:13:0 0,18,160:6:0 0,15,168:5:0 +X 3778 . T <*> 0 . DP=24;I16=14,9,0,0,859,32957,0,0,1208,66304,0,0,468,10372,0,0;QS=3,0;MQSB=0.836049;MQ0F=0 PL:DP:DV 0,36,227:12:0 0,18,157:6:0 0,15,167:5:0 +X 3779 . G <*> 0 . DP=24;I16=15,9,0,0,844,31206,0,0,1218,66404,0,0,493,10971,0,0;QS=3,0;MQSB=0.705785;MQ0F=0 PL:DP:DV 0,39,220:13:0 0,18,152:6:0 0,15,167:5:0 +X 3780 . C <*> 0 . DP=25;I16=14,10,0,0,829,29949,0,0,1268,69904,0,0,467,10295,0,0;QS=3,0;MQSB=0.765017;MQ0F=0 PL:DP:DV 0,39,235:13:0 0,18,144:6:0 0,15,169:5:0 +X 3781 . C <*> 0 . DP=26;I16=16,10,0,0,939,34725,0,0,1315,71373,0,0,492,10896,0,0;QS=3,0;MQSB=0.541994;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,139:6:0 0,15,175:5:0 +X 3782 . T <*> 0 . DP=26;I16=16,10,0,0,989,38031,0,0,1315,71373,0,0,493,10901,0,0;QS=3,0;MQSB=0.541994;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,169:6:0 0,15,176:5:0 +X 3783 . C <*> 0 . DP=26;I16=16,10,0,0,941,34801,0,0,1315,71373,0,0,492,10836,0,0;QS=3,0;MQSB=0.541994;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,155:6:0 0,15,162:5:0 +X 3784 . T <*> 0 . DP=27;I16=16,11,0,0,1001,38035,0,0,1375,74973,0,0,491,10801,0,0;QS=3,0;MQSB=0.467219;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,155:6:0 0,15,178:5:0 +X 3785 . G <*> 0 . DP=28;I16=15,10,0,0,922,36426,0,0,1305,71273,0,0,450,9916,0,0;QS=3,0;MQSB=0.674458;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,125:5:0 0,15,179:5:0 +X 3786 . T <*> 0 . DP=28;I16=16,11,0,0,935,35697,0,0,1375,74973,0,0,490,10774,0,0;QS=3,0;MQSB=0.467219;MQ0F=0 PL:DP:DV 0,48,250:16:0 0,18,145:6:0 0,15,186:5:0 +X 3787 . G <*> 0 . DP=28;I16=16,11,0,0,963,37951,0,0,1375,74973,0,0,489,10781,0,0;QS=3,0;MQSB=0.467219;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,143:6:0 0,15,177:5:0 +X 3788 . G <*> 0 . DP=26;I16=14,9,0,0,849,33683,0,0,1184,65386,0,0,459,10075,0,0;QS=3,0;MQSB=0.525788;MQ0F=0 PL:DP:DV 0,39,239:13:0 0,18,144:6:0 0,12,161:4:0 +X 3789 . G <*> 0 . DP=26;I16=13,10,0,0,807,31019,0,0,1231,68535,0,0,438,9474,0,0;QS=3,0;MQSB=0.445672;MQ0F=0 PL:DP:DV 0,39,251:13:0 0,18,133:6:0 0,12,161:4:0 +X 3790 . T <*> 0 . DP=26;I16=13,10,0,0,829,32293,0,0,1231,68535,0,0,435,9359,0,0;QS=3,0;MQSB=0.445672;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,150:6:0 0,12,159:4:0 +X 3791 . T <*> 0 . DP=26;I16=15,10,0,0,887,34725,0,0,1301,72235,0,0,478,10336,0,0;QS=3,0;MQSB=0.382304;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,136:6:0 0,12,159:4:0 +X 3792 . G A,<*> 0 . DP=26;I16=14,8,1,0,809,32805,38,1444,1175,66425,37,1369,417,8991,22,484;QS=2.92629,0.0737052,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.195278;BQB=1;MQ0F=0 PL:DP:DV 0,8,238,42,241,255:15:1 0,12,109,12,109,109:4:0 0,12,157,12,157,157:4:0 +X 3793 . A <*> 0 . DP=26;I16=15,8,0,0,833,33775,0,0,1212,67794,0,0,435,9363,0,0;QS=3,0;MQSB=0.195278;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,93:4:0 0,12,159:4:0 +X 3794 . C <*> 0 . DP=26;I16=15,9,0,0,845,33023,0,0,1241,68635,0,0,438,9324,0,0;QS=3,0;MQSB=0.439649;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,120:5:0 0,12,157:4:0 +X 3795 . C <*> 0 . DP=26;I16=14,9,0,0,865,35649,0,0,1231,68535,0,0,408,8622,0,0;QS=3,0;MQSB=0.563599;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,132:5:0 0,12,161:4:0 +X 3796 . T <*> 0 . DP=27;I16=15,11,0,0,964,38998,0,0,1361,75835,0,0,453,9821,0,0;QS=3,0;MQSB=0.334895;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,149:7:0 0,12,164:4:0 +X 3797 . A <*> 0 . DP=27;I16=15,10,0,0,848,32392,0,0,1301,72235,0,0,424,9172,0,0;QS=3,0;MQSB=0.382304;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,124:6:0 0,12,159:4:0 +X 3798 . T <*> 0 . DP=27;I16=14,11,0,0,921,37161,0,0,1301,72235,0,0,430,9554,0,0;QS=3,0;MQSB=0.283586;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,148:7:0 0,12,165:4:0 +X 3799 . T <*> 0 . DP=27;I16=15,11,0,0,913,35929,0,0,1361,75835,0,0,439,9729,0,0;QS=3,0;MQSB=0.334895;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,150:7:0 0,12,161:4:0 +X 3800 . C <*> 0 . DP=26;I16=13,10,0,0,866,36182,0,0,1181,65035,0,0,406,9092,0,0;QS=3,0;MQSB=0.272532;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,104:5:0 0,12,161:4:0 +X 3801 . T <*> 0 . DP=23;I16=12,10,0,0,804,33600,0,0,1121,61435,0,0,430,9750,0,0;QS=3,0;MQSB=0.217267;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,99:5:0 0,9,133:3:0 +X 3802 . G <*> 0 . DP=22;I16=10,9,0,0,730,30516,0,0,994,54486,0,0,380,8550,0,0;QS=3,0;MQSB=0.472367;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,106:4:0 0,9,130:3:0 +X 3803 . G <*> 0 . DP=22;I16=11,9,0,0,703,27393,0,0,1051,57735,0,0,405,9241,0,0;QS=3,0;MQSB=0.372419;MQ0F=0 PL:DP:DV 0,39,249:13:0 0,12,92:4:0 0,9,129:3:0 +X 3804 . A <*> 0 . DP=22;I16=11,9,0,0,740,30360,0,0,1051,57735,0,0,404,9274,0,0;QS=3,0;MQSB=0.372419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,98:4:0 0,9,132:3:0 +X 3805 . C <*> 0 . DP=22;I16=12,9,0,0,737,29243,0,0,1061,57835,0,0,428,9950,0,0;QS=3,0;MQSB=0.262932;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,81:4:0 0,9,130:3:0 +X 3806 . A <*> 0 . DP=22;I16=12,9,0,0,798,32550,0,0,1061,57835,0,0,426,9968,0,0;QS=3,0;MQSB=0.262932;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,105:4:0 0,9,128:3:0 +X 3807 . C <*> 0 . DP=22;I16=10,9,0,0,664,25304,0,0,994,54486,0,0,377,8885,0,0;QS=3,0;MQSB=0.472367;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,83:4:0 0,9,115:3:0 +X 3808 . G <*> 0 . DP=21;I16=9,9,0,0,653,25297,0,0,957,53117,0,0,375,8873,0,0;QS=3,0;MQSB=0.597145;MQ0F=0 PL:DP:DV 0,33,233:11:0 0,12,109:4:0 0,9,132:3:0 +X 3809 . T <*> 0 . DP=22;I16=11,10,0,0,779,32151,0,0,1084,60066,0,0,416,9810,0,0;QS=3,0;MQSB=0.285029;MQ0F=0 PL:DP:DV 0,39,249:13:0 0,12,115:4:0 0,12,161:4:0 +X 3810 . C <*> 0 . DP=23;I16=9,11,0,0,811,34815,0,0,1077,60317,0,0,369,8739,0,0;QS=3,0;MQSB=0.499893;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,112:4:0 0,12,153:4:0 +X 3811 . A C,<*> 0 . DP=23;I16=9,11,2,0,777,32631,39,785,1077,60317,67,3349,367,8669,42,914;QS=2.94104,0.0589569,0;VDB=0.18;SGB=0.346553;RPB=0.425;MQB=0.25;MQSB=0.246128;BQB=0.025;MQ0F=0 PL:DP:DV 0,15,248,36,254,255:14:2 0,12,116,12,116,116:4:0 0,12,158,12,158,158:4:0 +X 3812 . T <*> 0 . DP=23;I16=10,11,0,0,802,32860,0,0,1084,60066,0,0,405,9447,0,0;QS=3,0;MQSB=0.187115;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,114:4:0 0,12,160:4:0 +X 3813 . A <*> 0 . DP=22;I16=10,11,0,0,815,35077,0,0,1084,60066,0,0,402,9330,0,0;QS=3,0;MQSB=0.187115;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,119:4:0 0,12,170:4:0 +X 3814 . G <*> 0 . DP=21;I16=8,11,0,0,775,33731,0,0,1037,58597,0,0,375,8605,0,0;QS=3,0;MQSB=0.41781;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,113:4:0 0,12,163:4:0 +X 3815 . A <*> 0 . DP=20;I16=8,11,0,0,708,29130,0,0,1010,57328,0,0,397,9049,0,0;QS=3,0;MQSB=0.373354;MQ0F=0 PL:DP:DV 0,33,239:11:0 0,12,110:4:0 0,12,162:4:0 +X 3816 . A <*> 0 . DP=20;I16=8,11,0,0,729,31027,0,0,1010,57328,0,0,395,8933,0,0;QS=3,0;MQSB=0.373354;MQ0F=0 PL:DP:DV 0,33,248:11:0 0,12,104:4:0 0,12,160:4:0 +X 3817 . A <*> 0 . DP=20;I16=8,11,0,0,752,31580,0,0,1010,57328,0,0,393,8833,0,0;QS=3,0;MQSB=0.373354;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,110:4:0 0,12,161:4:0 +X 3818 . T <*> 0 . DP=20;I16=8,11,0,0,728,30466,0,0,1010,57328,0,0,391,8749,0,0;QS=3,0;MQSB=0.373354;MQ0F=0 PL:DP:DV 0,33,252:11:0 0,12,115:4:0 0,12,160:4:0 +X 3819 . A <*> 0 . DP=21;I16=9,11,0,0,790,34094,0,0,1039,58169,0,0,389,8681,0,0;QS=3,0;MQSB=0.247381;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,121:4:0 0,12,167:4:0 +X 3820 . G <*> 0 . DP=21;I16=9,11,0,0,788,33636,0,0,1039,58169,0,0,388,8630,0,0;QS=3,0;MQSB=0.247381;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,112:4:0 0,12,157:4:0 +X 3821 . A <*> 0 . DP=22;I16=10,11,0,0,832,35864,0,0,1099,61769,0,0,387,8597,0,0;QS=3,0;MQSB=0.317882;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,115:4:0 0,12,168:4:0 +X 3822 . G <*> 0 . DP=22;I16=10,11,0,0,810,33228,0,0,1099,61769,0,0,386,8532,0,0;QS=3,0;MQSB=0.317882;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,103:4:0 0,12,157:4:0 +X 3823 . T <*> 0 . DP=22;I16=9,11,0,0,753,30705,0,0,1042,58520,0,0,380,8460,0,0;QS=3,0;MQSB=0.434285;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,102:4:0 0,12,163:4:0 +X 3824 . C <*> 0 . DP=22;I16=10,11,0,0,802,32368,0,0,1099,61769,0,0,384,8456,0,0;QS=3,0;MQSB=0.317882;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,105:4:0 0,12,159:4:0 +X 3825 . C <*> 0 . DP=23;I16=10,11,0,0,813,33955,0,0,1079,59889,0,0,379,8387,0,0;QS=3,0;MQSB=0.317882;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,130:5:0 0,12,157:4:0 +X 3826 . T <*> 0 . DP=23;I16=11,11,0,0,827,34611,0,0,1136,63138,0,0,381,8357,0,0;QS=3,0;MQSB=0.232836;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,133:5:0 0,12,155:4:0 +X 3827 . G <*> 0 . DP=23;I16=11,10,0,0,820,34130,0,0,1076,59538,0,0,355,7715,0,0;QS=3,0;MQSB=0.269397;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,121:4:0 0,12,162:4:0 +X 3828 . C <*> 0 . DP=23;I16=11,10,0,0,805,33147,0,0,1076,59538,0,0,354,7720,0,0;QS=3,0;MQSB=0.269397;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,114:4:0 0,12,157:4:0 +X 3829 . A <*> 0 . DP=22;I16=9,11,0,0,763,31295,0,0,1069,59789,0,0,369,8241,0,0;QS=3,0;MQSB=0.477679;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,132:5:0 0,12,158:4:0 +X 3830 . A <*> 0 . DP=23;I16=11,11,0,0,825,32693,0,0,1136,63138,0,0,377,8321,0,0;QS=3,0;MQSB=0.232836;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,143:5:0 0,12,150:4:0 +X 3831 . C A,<*> 0 . DP=23;I16=10,11,1,0,802,32198,14,196,1126,63038,10,100,370,8294,7,49;QS=2.97758,0.0224215,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.232836;BQB=1;MQ0F=0 PL:DP:DV 0,27,255,36,255,255:13:1 0,15,134,15,134,134:5:0 0,12,149,12,149,149:4:0 +X 3832 . A <*> 0 . DP=24;I16=12,11,0,0,836,32436,0,0,1196,66738,0,0,377,8389,0,0;QS=3,0;MQSB=0.291845;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,136:5:0 0,12,139:4:0 +X 3833 . C <*> 0 . DP=23;I16=10,11,0,0,690,24938,0,0,1076,59538,0,0,377,8409,0,0;QS=3,0;MQSB=0.175325;MQ0F=0 PL:DP:DV 0,36,249:12:0 0,15,113:5:0 0,12,131:4:0 +X 3834 . G <*> 0 . DP=22;I16=9,10,0,0,684,26250,0,0,1037,58597,0,0,357,8079,0,0;QS=3,0;MQSB=0.124514;MQ0F=0 PL:DP:DV 0,33,242:11:0 0,12,122:4:0 0,12,156:4:0 +X 3835 . T <*> 0 . DP=22;I16=10,11,0,0,773,30373,0,0,1076,59538,0,0,381,8475,0,0;QS=3,0;MQSB=0.175325;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,140:5:0 0,12,153:4:0 +X 3836 . G C,<*> 0 . DP=24;I16=10,12,1,0,833,33183,14,196,1132,61648,10,100,378,8412,2,4;QS=2.97647,0.0235294,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.251407;BQB=1;MQ0F=0 PL:DP:DV 0,27,255,36,255,255:13:1 0,15,149,15,149,149:5:0 0,15,188,15,188,188:5:0 +X 3837 . G <*> 0 . DP=24;I16=8,14,0,0,759,26931,0,0,1135,61999,0,0,399,8955,0,0;QS=3,0;MQSB=0.291667;MQ0F=0 PL:DP:DV 0,33,245:11:0 0,18,149:6:0 0,15,157:5:0 +X 3838 . C <*> 0 . DP=24;I16=10,14,0,0,817,28975,0,0,1202,65348,0,0,409,8945,0,0;QS=3,0;MQSB=0.122456;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,143:6:0 0,15,148:5:0 +X 3839 . C <*> 0 . DP=23;I16=9,13,0,0,688,22248,0,0,1132,61648,0,0,386,8238,0,0;QS=3,0;MQSB=0.248197;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,123:6:0 0,12,112:4:0 +X 3840 . G <*> 0 . DP=23;I16=9,14,0,0,793,27941,0,0,1192,65248,0,0,413,8809,0,0;QS=3,0;MQSB=0.211072;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,160:6:0 0,15,146:5:0 +X 3841 . T <*> 0 . DP=23;I16=9,14,0,0,867,33103,0,0,1192,65248,0,0,414,8734,0,0;QS=3,0;MQSB=0.211072;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,167:6:0 0,15,162:5:0 +X 3842 . C <*> 0 . DP=23;I16=9,14,0,0,890,34728,0,0,1192,65248,0,0,415,8689,0,0;QS=3,0;MQSB=0.211072;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,167:6:0 0,15,159:5:0 +X 3843 . T <*> 0 . DP=24;I16=9,14,0,0,896,35122,0,0,1192,65248,0,0,416,8674,0,0;QS=3,0;MQSB=0.211072;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,164:6:0 0,15,159:5:0 +X 3844 . G <*> 0 . DP=26;I16=10,16,0,0,959,35715,0,0,1372,76048,0,0,442,9314,0,0;QS=3,0;MQSB=0.220358;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,177:7:0 0,18,172:6:0 +X 3845 . T <*> 0 . DP=26;I16=10,16,0,0,970,36442,0,0,1372,76048,0,0,444,9310,0,0;QS=3,0;MQSB=0.220358;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,186:7:0 0,18,166:6:0 +X 3846 . G <*> 0 . DP=27;I16=10,17,0,0,993,37297,0,0,1432,79648,0,0,446,9338,0,0;QS=3,0;MQSB=0.195223;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,175:7:0 0,21,172:7:0 +X 3847 . T <*> 0 . DP=27;I16=10,16,0,0,952,35268,0,0,1372,76048,0,0,423,8723,0,0;QS=3,0;MQSB=0.220358;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,170:6:0 0,21,189:7:0 +X 3848 . C <*> 0 . DP=27;I16=10,17,0,0,1025,39533,0,0,1432,79648,0,0,449,9341,0,0;QS=3,0;MQSB=0.195223;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,177:7:0 0,21,188:7:0 +X 3849 . T <*> 0 . DP=27;I16=9,17,0,0,987,37685,0,0,1395,78279,0,0,450,9368,0,0;QS=3,0;MQSB=0.282527;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,179:7:0 0,21,190:7:0 +X 3850 . G <*> 0 . DP=26;I16=9,17,0,0,957,35751,0,0,1395,78279,0,0,452,9428,0,0;QS=3,0;MQSB=0.282527;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,179:7:0 0,21,182:7:0 +X 3851 . G <*> 0 . DP=26;I16=9,17,0,0,965,36475,0,0,1395,78279,0,0,453,9469,0,0;QS=3,0;MQSB=0.282527;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,177:7:0 0,21,183:7:0 +X 3852 . C <*> 0 . DP=26;I16=9,16,0,0,921,34525,0,0,1335,74679,0,0,444,9440,0,0;QS=3,0;MQSB=0.310905;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,163:6:0 0,21,179:7:0 +X 3853 . T <*> 0 . DP=28;I16=10,18,0,0,1050,40222,0,0,1484,82720,0,0,455,9641,0,0;QS=3,0;MQSB=0.515783;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,185:7:0 0,21,192:7:0 +X 3854 . T <*> 0 . DP=28;I16=10,17,0,0,955,34605,0,0,1455,81879,0,0,451,9709,0,0;QS=3,0;MQSB=0.359211;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,171:6:0 0,18,178:6:0 +X 3855 . C <*> 0 . DP=29;I16=10,18,0,0,992,36040,0,0,1515,85479,0,0,438,9264,0,0;QS=3,0;MQSB=0.331344;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,139:5:0 0,21,175:7:0 +X 3856 . T <*> 0 . DP=30;I16=10,18,0,0,1033,38725,0,0,1546,88238,0,0,464,9982,0,0;QS=3,0;MQSB=0.190183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,163:6:0 0,21,185:7:0 +X 3857 . C <*> 0 . DP=30;I16=10,19,0,0,1077,40979,0,0,1575,89079,0,0,447,9505,0,0;QS=3,0;MQSB=0.306875;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,154:5:0 0,24,194:8:0 +X 3858 . T <*> 0 . DP=31;I16=10,21,0,0,1141,42567,0,0,1695,96279,0,0,477,10255,0,0;QS=3,0;MQSB=0.266219;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,171:6:0 0,24,208:8:0 +X 3859 . C <*> 0 . DP=32;I16=10,21,0,0,950,30078,0,0,1695,96279,0,0,484,10416,0,0;QS=3,0;MQSB=0.266219;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,136:6:0 0,24,156:8:0 +X 3860 . G <*> 0 . DP=32;I16=10,22,0,0,1070,37794,0,0,1755,99879,0,0,516,11240,0,0;QS=3,0;MQSB=0.249261;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,154:6:0 0,27,209:9:0 +X 3861 . C <*> 0 . DP=33;I16=11,20,0,0,1133,42547,0,0,1672,94048,0,0,517,11391,0,0;QS=3,0;MQSB=0.19205;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,162:6:0 0,24,199:8:0 +X 3862 . T <*> 0 . DP=34;I16=11,22,0,0,1241,47443,0,0,1792,101248,0,0,526,11518,0,0;QS=3,0;MQSB=0.161533;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,185:7:0 0,27,221:9:0 +X 3863 . T <*> 0 . DP=34;I16=12,22,0,0,1200,43542,0,0,1852,104848,0,0,541,11685,0,0;QS=3,0;MQSB=0.210327;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,199:7:0 0,27,213:9:0 +X 3864 . A <*> 0 . DP=33;I16=11,22,0,0,1238,47448,0,0,1792,101248,0,0,550,11790,0,0;QS=3,0;MQSB=0.161533;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,210:7:0 0,27,230:9:0 +X 3865 . G <*> 0 . DP=34;I16=11,23,0,0,1251,47113,0,0,1852,104848,0,0,559,11933,0,0;QS=3,0;MQSB=0.149071;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,200:7:0 0,27,212:9:0 +X 3866 . C <*> 0 . DP=33;I16=11,21,0,0,1165,43545,0,0,1732,97648,0,0,545,11489,0,0;QS=3,0;MQSB=0.175751;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,189:7:0 0,24,197:8:0 +X 3867 . A <*> 0 . DP=33;I16=11,22,0,0,1152,41510,0,0,1792,101248,0,0,580,12284,0,0;QS=3,0;MQSB=0.161533;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,188:7:0 0,27,195:9:0 +X 3868 . T <*> 0 . DP=33;I16=11,22,0,0,1255,48141,0,0,1792,101248,0,0,590,12494,0,0;QS=3,0;MQSB=0.161533;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,202:7:0 0,27,221:9:0 +X 3869 . C <*> 0 . DP=33;I16=11,21,0,0,1169,43987,0,0,1732,97648,0,0,589,12623,0,0;QS=3,0;MQSB=0.175751;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,164:6:0 0,27,211:9:0 +X 3870 . T <*> 0 . DP=34;I16=11,23,0,0,1262,47808,0,0,1852,104848,0,0,608,12932,0,0;QS=3,0;MQSB=0.149071;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,215:8:0 0,27,211:9:0 +X 3871 . T <*> 0 . DP=36;I16=11,25,0,0,1341,50655,0,0,1972,112048,0,0,617,13157,0,0;QS=3,0;MQSB=0.128391;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,221:8:0 0,27,223:9:0 +X 3872 . G <*> 0 . DP=36;I16=11,25,0,0,1287,47095,0,0,1972,112048,0,0,626,13322,0,0;QS=3,0;MQSB=0.128391;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,211:8:0 0,27,200:9:0 +X 3873 . T <*> 0 . DP=35;I16=10,24,0,0,1242,46680,0,0,1852,104848,0,0,626,13428,0,0;QS=3,0;MQSB=0.0982034;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,194:7:0 0,24,212:8:0 +X 3874 . T <*> 0 . DP=36;I16=12,24,0,0,1290,47660,0,0,1972,112048,0,0,646,13774,0,0;QS=3,0;MQSB=0.182088;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,24,228:8:0 0,24,204:8:0 +X 3875 . T <*> 0 . DP=37;I16=13,24,0,0,1324,48418,0,0,2029,115297,0,0,657,14061,0,0;QS=3,0;MQSB=0.117872;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,231:8:0 0,24,197:8:0 +X 3876 . C <*> 0 . DP=37;I16=13,22,0,0,1248,45354,0,0,1909,108097,0,0,623,13325,0,0;QS=3,0;MQSB=0.140806;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,196:7:0 0,24,180:8:0 +X 3877 . C <*> 0 . DP=37;I16=13,24,0,0,1363,51201,0,0,2029,115297,0,0,681,14765,0,0;QS=3,0;MQSB=0.117872;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,217:8:0 0,24,196:8:0 +X 3878 . A <*> 0 . DP=37;I16=13,23,0,0,1309,48045,0,0,1969,111697,0,0,670,14654,0,0;QS=3,0;MQSB=0.128568;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,24,218:8:0 0,24,188:8:0 +X 3879 . A <*> 0 . DP=38;I16=14,24,0,0,1453,56567,0,0,2066,116666,0,0,703,15543,0,0;QS=3,0;MQSB=0.076112;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,226:8:0 0,24,206:8:0 +X 3880 . G <*> 0 . DP=37;I16=14,22,0,0,1311,48735,0,0,1946,109466,0,0,689,15267,0,0;QS=3,0;MQSB=0.094094;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,24,209:8:0 0,24,183:8:0 +X 3881 . G <*> 0 . DP=37;I16=14,21,0,0,1200,42778,0,0,1886,105866,0,0,690,15578,0,0;QS=3,0;MQSB=0.105399;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,18,178:6:0 0,24,174:8:0 +X 3882 . T <*> 0 . DP=37;I16=14,21,0,0,1192,42352,0,0,1886,105866,0,0,684,15348,0,0;QS=3,0;MQSB=0.105399;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,21,189:7:0 0,21,178:7:0 +X 3883 . C <*> 0 . DP=38;I16=15,22,0,0,1295,46659,0,0,2006,113066,0,0,717,16279,0,0;QS=3,0;MQSB=0.124405;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,205:8:0 0,24,171:8:0 +X 3884 . C <*> 0 . DP=39;I16=16,23,0,0,1363,49387,0,0,2103,118035,0,0,749,17141,0,0;QS=3,0;MQSB=0.0760633;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,202:8:0 0,27,212:9:0 +X 3885 . T <*> 0 . DP=40;I16=16,24,0,0,1445,53663,0,0,2163,121635,0,0,754,17262,0,0;QS=3,0;MQSB=0.0679472;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,24,219:8:0 0,27,214:9:0 +X 3886 . C <*> 0 . DP=39;I16=16,23,0,0,1370,49762,0,0,2103,118035,0,0,761,17421,0,0;QS=3,0;MQSB=0.0760633;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,24,199:8:0 0,24,191:8:0 +X 3887 . C <*> 0 . DP=39;I16=16,23,0,0,1364,49222,0,0,2103,118035,0,0,767,17567,0,0;QS=3,0;MQSB=0.0760633;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,24,194:8:0 0,24,201:8:0 +X 3888 . C <*> 0 . DP=39;I16=15,23,0,0,1387,51885,0,0,2043,114435,0,0,747,17073,0,0;QS=3,0;MQSB=0.0555905;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,195:8:0 0,24,208:8:0 +X 3889 . A <*> 0 . DP=38;I16=15,23,0,0,1364,49918,0,0,2066,116666,0,0,777,17811,0,0;QS=3,0;MQSB=0.112471;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,202:8:0 0,24,218:8:0 +X 3890 . C <*> 0 . DP=38;I16=14,23,0,0,1362,51064,0,0,2006,113066,0,0,757,17329,0,0;QS=3,0;MQSB=0.0844255;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,203:8:0 0,24,216:8:0 +X 3891 . A <*> 0 . DP=39;I16=15,24,0,0,1466,56312,0,0,2126,120266,0,0,786,18076,0,0;QS=3,0;MQSB=0.102114;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,203:8:0 0,27,239:9:0 +X 3892 . G <*> 0 . DP=38;I16=15,23,0,0,1340,48838,0,0,2066,116666,0,0,792,18226,0,0;QS=3,0;MQSB=0.112471;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,186:8:0 0,27,208:9:0 +X 3893 . T <*> 0 . DP=39;I16=15,24,0,0,1348,48170,0,0,2126,120266,0,0,798,18404,0,0;QS=3,0;MQSB=0.102114;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,196:8:0 0,27,212:9:0 +X 3894 . G <*> 0 . DP=39;I16=15,23,0,0,1364,49900,0,0,2066,116666,0,0,779,17937,0,0;QS=3,0;MQSB=0.112471;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,202:8:0 0,27,208:9:0 +X 3895 . T <*> 0 . DP=39;I16=15,24,0,0,1375,49773,0,0,2126,120266,0,0,810,18752,0,0;QS=3,0;MQSB=0.102114;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,202:8:0 0,27,225:9:0 +X 3896 . A <*> 0 . DP=40;I16=15,24,0,0,1468,57326,0,0,2126,120266,0,0,815,18923,0,0;QS=3,0;MQSB=0.102114;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,224:8:0 0,27,233:9:0 +X 3897 . G <*> 0 . DP=40;I16=15,24,0,0,1468,56812,0,0,2126,120266,0,0,819,19021,0,0;QS=3,0;MQSB=0.102114;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,21,199:7:0 0,30,234:10:0 +X 3898 . C <*> 0 . DP=40;I16=15,23,0,0,1487,59351,0,0,2066,116666,0,0,813,19023,0,0;QS=3,0;MQSB=0.112471;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,18,186:6:0 0,30,238:10:0 +X 3899 . A <*> 0 . DP=40;I16=15,24,0,0,1449,55055,0,0,2126,120266,0,0,829,19293,0,0;QS=3,0;MQSB=0.102114;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,21,191:7:0 0,30,231:10:0 +X 3900 . T <*> 0 . DP=40;I16=15,24,0,0,1458,55516,0,0,2126,120266,0,0,833,19417,0,0;QS=3,0;MQSB=0.102114;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,21,197:7:0 0,30,240:10:0 +X 3901 . G <*> 0 . DP=40;I16=14,22,0,0,1303,48245,0,0,1969,111697,0,0,761,17639,0,0;QS=3,0;MQSB=0.180757;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,18,154:6:0 0,27,218:9:0 +X 3902 . C <*> 0 . DP=40;I16=15,24,0,0,1436,55412,0,0,2126,120266,0,0,837,19537,0,0;QS=3,0;MQSB=0.102114;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,21,166:7:0 0,30,217:10:0 +X 3903 . A <*> 0 . DP=42;I16=15,24,0,0,1299,45567,0,0,2089,117417,0,0,814,19008,0,0;QS=3,0;MQSB=0.0901152;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,175:8:0 0,30,204:10:0 +X 3904 . C <*> 0 . DP=42;I16=15,24,0,0,1439,54545,0,0,2086,117066,0,0,815,19113,0,0;QS=3,0;MQSB=0.0426917;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,191:8:0 0,30,244:10:0 +X 3905 . C <*> 0 . DP=42;I16=15,25,0,0,1572,63314,0,0,2146,120666,0,0,822,19192,0,0;QS=3,0;MQSB=0.0381122;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,212:8:0 0,33,255:11:0 +X 3906 . T <*> 0 . DP=42;I16=16,25,0,0,1593,63039,0,0,2206,124266,0,0,846,19758,0,0;QS=3,0;MQSB=0.0536599;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,210:8:0 0,33,253:11:0 +X 3907 . G <*> 0 . DP=42;I16=16,25,0,0,1558,60192,0,0,2206,124266,0,0,846,19776,0,0;QS=3,0;MQSB=0.0536599;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,203:8:0 0,33,249:11:0 +X 3908 . C <*> 0 . DP=42;I16=16,25,0,0,1514,58968,0,0,2206,124266,0,0,845,19777,0,0;QS=3,0;MQSB=0.0536599;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,193:8:0 0,33,244:11:0 +X 3909 . T <*> 0 . DP=43;I16=16,25,0,0,1491,55895,0,0,2201,123691,0,0,835,19697,0,0;QS=3,0;MQSB=0.0757469;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,24,202:8:0 0,30,237:10:0 +X 3910 . A <*> 0 . DP=40;I16=16,23,0,0,1432,53926,0,0,2081,116491,0,0,844,19724,0,0;QS=3,0;MQSB=0.0949554;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,21,193:7:0 0,30,224:10:0 +X 3911 . C <*> 0 . DP=40;I16=16,23,0,0,1440,55290,0,0,2081,116491,0,0,843,19613,0,0;QS=3,0;MQSB=0.0949554;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,21,184:7:0 0,30,214:10:0 +X 3912 . A C,<*> 0 . DP=41;I16=17,22,0,1,1358,49508,16,256,2081,116491,60,3600,830,19358,11,121;QS=2.95181,0.0481928,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.125266;BQB=1;MQ0F=0 PL:DP:DV 0,69,255,69,255,255:23:0 0,21,166,21,166,166:7:0 0,14,202,27,205,208:10:1 +X 3913 . C <*> 0 . DP=40;I16=16,23,0,0,1494,59096,0,0,2081,116491,0,0,824,19100,0,0;QS=3,0;MQSB=0.0949554;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,21,183:7:0 0,30,234:10:0 +X 3914 . T <*> 0 . DP=42;I16=16,24,0,0,1512,59342,0,0,2141,120091,0,0,823,19007,0,0;QS=3,0;MQSB=0.0846181;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,21,192:7:0 0,30,228:10:0 +X 3915 . C <*> 0 . DP=42;I16=16,24,0,0,1537,60953,0,0,2141,120091,0,0,799,18321,0,0;QS=3,0;MQSB=0.0846181;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,18,176:6:0 0,30,229:10:0 +X 3916 . C <*> 0 . DP=42;I16=16,25,0,0,1618,66342,0,0,2201,123691,0,0,825,18919,0,0;QS=3,0;MQSB=0.0757469;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,21,190:7:0 0,30,251:10:0 +X 3917 . T <*> 0 . DP=43;I16=16,25,0,0,1601,65219,0,0,2201,123691,0,0,825,18875,0,0;QS=3,0;MQSB=0.0757469;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,21,191:7:0 0,30,254:10:0 +X 3918 . T <*> 0 . DP=43;I16=16,25,0,0,1541,60711,0,0,2201,123691,0,0,801,18239,0,0;QS=3,0;MQSB=0.0757469;MQ0F=0 PL:DP:DV 0,75,255:25:0 0,18,179:6:0 0,30,254:10:0 +X 3919 . C <*> 0 . DP=42;I16=15,26,0,0,1621,66337,0,0,2232,126450,0,0,826,18786,0,0;QS=3,0;MQSB=0.110793;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,21,200:7:0 0,30,242:10:0 +X 3920 . T <*> 0 . DP=42;I16=15,26,0,0,1605,64327,0,0,2232,126450,0,0,825,18691,0,0;QS=3,0;MQSB=0.110793;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,21,207:7:0 0,30,251:10:0 +X 3921 . T <*> 0 . DP=42;I16=15,26,0,0,1519,58507,0,0,2232,126450,0,0,824,18630,0,0;QS=3,0;MQSB=0.110793;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,21,201:7:0 0,30,242:10:0 +X 3922 . A <*> 0 . DP=42;I16=14,26,0,0,1539,61289,0,0,2195,125081,0,0,819,18545,0,0;QS=3,0;MQSB=0.168991;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,18,179:6:0 0,30,244:10:0 +X 3923 . G <*> 0 . DP=41;I16=14,25,0,0,1515,60945,0,0,2135,121481,0,0,792,17834,0,0;QS=3,0;MQSB=0.182501;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,18,172:6:0 0,30,240:10:0 +X 3924 . G <*> 0 . DP=41;I16=13,26,0,0,1524,61106,0,0,2135,121481,0,0,808,18356,0,0;QS=3,0;MQSB=0.128469;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,18,158:6:0 0,30,247:10:0 +X 3925 . G <*> 0 . DP=41;I16=14,25,0,0,1425,55687,0,0,2135,121481,0,0,788,17758,0,0;QS=3,0;MQSB=0.182501;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,15,134:5:0 0,30,245:10:0 +X 3926 . C <*> 0 . DP=41;I16=14,26,0,0,1512,59674,0,0,2195,125081,0,0,811,18393,0,0;QS=3,0;MQSB=0.168991;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,18,152:6:0 0,30,237:10:0 +X 3927 . T <*> 0 . DP=41;I16=14,26,0,0,1512,59566,0,0,2195,125081,0,0,808,18384,0,0;QS=3,0;MQSB=0.168991;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,18,160:6:0 0,30,237:10:0 +X 3928 . G <*> 0 . DP=41;I16=14,25,0,0,1479,58495,0,0,2135,121481,0,0,779,17731,0,0;QS=3,0;MQSB=0.182501;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,18,149:6:0 0,27,233:9:0 +X 3929 . A <*> 0 . DP=41;I16=13,26,0,0,1452,56436,0,0,2135,121481,0,0,796,18256,0,0;QS=3,0;MQSB=0.128469;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,18,161:6:0 0,30,220:10:0 +X 3930 . T <*> 0 . DP=40;I16=13,25,0,0,1387,52929,0,0,2078,118232,0,0,767,17521,0,0;QS=3,0;MQSB=0.25797;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,15,149:5:0 0,30,224:10:0 +X 3931 . A <*> 0 . DP=40;I16=13,25,0,0,1387,52877,0,0,2078,118232,0,0,761,17439,0,0;QS=3,0;MQSB=0.25797;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,18,166:6:0 0,27,222:9:0 +X 3932 . T <*> 0 . DP=39;I16=12,26,0,0,1394,53644,0,0,2078,118232,0,0,780,17964,0,0;QS=3,0;MQSB=0.190372;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,18,161:6:0 0,30,231:10:0 +X 3933 . T <*> 0 . DP=38;I16=12,24,0,0,1389,54743,0,0,1958,111032,0,0,752,17366,0,0;QS=3,0;MQSB=0.218161;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,18,166:6:0 0,24,220:8:0 +X 3934 . C <*> 0 . DP=38;I16=12,25,0,0,1395,54915,0,0,2018,114632,0,0,768,17758,0,0;QS=3,0;MQSB=0.203497;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,18,152:6:0 0,27,209:9:0 +X 3935 . C <*> 0 . DP=38;I16=12,24,0,0,1239,44621,0,0,1958,111032,0,0,737,17075,0,0;QS=3,0;MQSB=0.218161;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,15,134:5:0 0,27,170:9:0 +X 3936 . A G,<*> 0 . DP=37;I16=5,6,6,17,424,16384,801,30271,609,34563,1314,77018,225,5325,511,11851;QS=0.87994,2.12006,0;VDB=0.0574114;SGB=-4.60123;RPB=0.741697;MQB=0.812605;MQSB=0.143788;BQB=0.883831;MQ0F=0 PL:DP:DV 233,0,206,255,239,255:20:11 77,0,58,83,70,141:6:4 196,24,0,196,24,196:8:8 +X 3937 . C <*> 0 . DP=36;I16=11,24,0,0,1155,39875,0,0,1952,112422,0,0,745,17291,0,0;QS=3,0;MQSB=0.219636;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,18,143:6:0 0,24,156:8:0 +X 3938 . G <*> 0 . DP=35;I16=11,23,0,0,1155,41761,0,0,1892,108822,0,0,737,17079,0,0;QS=3,0;MQSB=0.231054;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,15,119:5:0 0,24,176:8:0 +X 3939 . C <*> 0 . DP=35;I16=11,22,0,0,1273,50651,0,0,1832,105222,0,0,703,16221,0,0;QS=3,0;MQSB=0.243713;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,15,135:5:0 0,21,174:7:0 +X 3940 . A <*> 0 . DP=35;I16=11,22,0,0,1148,42754,0,0,1832,105222,0,0,691,15867,0,0;QS=3,0;MQSB=0.243713;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,15,117:5:0 0,21,163:7:0 +X 3941 . C <*> 0 . DP=35;I16=11,22,0,0,1216,47488,0,0,1832,105222,0,0,688,15892,0,0;QS=3,0;MQSB=0.243713;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,15,133:5:0 0,21,181:7:0 +X 3942 . C <*> 0 . DP=35;I16=11,23,0,0,1336,54166,0,0,1892,108822,0,0,690,15772,0,0;QS=3,0;MQSB=0.231054;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,15,140:5:0 0,24,195:8:0 +X 3943 . T <*> 0 . DP=35;I16=11,23,0,0,1296,51618,0,0,1892,108822,0,0,676,15406,0,0;QS=3,0;MQSB=0.231054;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,15,142:5:0 0,24,195:8:0 +X 3944 . G <*> 0 . DP=34;I16=10,22,0,0,1199,46445,0,0,1803,104381,0,0,654,14954,0,0;QS=3,0;MQSB=0.1117;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,149:5:0 0,24,195:8:0 +X 3945 . C <*> 0 . DP=33;I16=10,22,0,0,1256,51226,0,0,1772,101622,0,0,649,14657,0,0;QS=3,0;MQSB=0.187579;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,142:5:0 0,21,177:7:0 +X 3946 . T <*> 0 . DP=33;I16=10,21,0,0,1170,45884,0,0,1712,98022,0,0,609,13599,0,0;QS=3,0;MQSB=0.199344;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,144:5:0 0,18,158:6:0 +X 3947 . A <*> 0 . DP=32;I16=10,21,0,0,1094,41048,0,0,1712,98022,0,0,620,13820,0,0;QS=3,0;MQSB=0.199344;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,128:5:0 0,18,149:6:0 +X 3948 . C <*> 0 . DP=32;I16=10,20,0,0,1134,45104,0,0,1652,94422,0,0,596,13344,0,0;QS=3,0;MQSB=0.212591;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,105:4:0 0,18,155:6:0 +X 3949 . A C,<*> 0 . DP=32;I16=10,17,0,1,1027,39909,24,576,1472,83622,60,3600,541,12211,25,625;QS=2.85093,0.149068,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.244621;BQB=1;MQ0F=0 PL:DP:DV 0,60,255,60,255,255:20:0 0,9,89,9,89,89:3:0 9,0,107,21,110,124:5:1 +X 3950 . C <*> 0 . DP=33;I16=11,21,0,0,1191,46247,0,0,1772,101622,0,0,576,12680,0,0;QS=3,0;MQSB=0.257801;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,15,118:5:0 0,18,168:6:0 +X 3951 . T <*> 0 . DP=34;I16=12,19,0,0,1148,44272,0,0,1712,98022,0,0,530,11670,0,0;QS=3,0;MQSB=0.354733;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,15,146:5:0 0,15,152:5:0 +X 3952 . C <*> 0 . DP=35;I16=13,20,0,0,1176,43762,0,0,1832,105222,0,0,545,12025,0,0;QS=3,0;MQSB=0.394875;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,18,158:6:0 0,15,143:5:0 +X 3953 . C <*> 0 . DP=34;I16=13,20,0,0,1246,48436,0,0,1863,107981,0,0,538,11772,0,0;QS=3,0;MQSB=0.252983;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,18,163:6:0 0,18,168:6:0 +X 3954 . T <*> 0 . DP=33;I16=13,19,0,0,1195,45815,0,0,1803,104381,0,0,526,11438,0,0;QS=3,0;MQSB=0.264585;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,18,171:6:0 0,18,167:6:0 +X 3955 . T <*> 0 . DP=32;I16=13,18,0,0,1180,46092,0,0,1743,100781,0,0,515,11139,0,0;QS=3,0;MQSB=0.277468;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,173:6:0 0,18,174:6:0 +X 3956 . C <*> 0 . DP=32;I16=13,18,0,0,1181,47021,0,0,1743,100781,0,0,504,10874,0,0;QS=3,0;MQSB=0.277468;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,167:6:0 0,18,167:6:0 +X 3957 . T <*> 0 . DP=31;I16=13,17,0,0,1153,46051,0,0,1683,97181,0,0,494,10642,0,0;QS=3,0;MQSB=0.291833;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,161:6:0 0,15,162:5:0 +X 3958 . T <*> 0 . DP=31;I16=13,16,0,0,1070,40600,0,0,1623,93581,0,0,483,10393,0,0;QS=3,0;MQSB=0.307929;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,139:5:0 0,15,157:5:0 +X 3959 . A <*> 0 . DP=30;I16=14,15,0,0,1062,39758,0,0,1623,93581,0,0,474,10176,0,0;QS=3,0;MQSB=0.377103;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,118:4:0 0,15,154:5:0 +X 3960 . T <*> 0 . DP=30;I16=14,15,0,0,995,36027,0,0,1623,93581,0,0,464,9892,0,0;QS=3,0;MQSB=0.377103;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,105:4:0 0,15,142:5:0 +X 3961 . G <*> 0 . DP=29;I16=12,16,0,0,1067,40899,0,0,1586,92212,0,0,457,9739,0,0;QS=3,0;MQSB=0.455864;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,114:4:0 0,12,122:4:0 +X 3962 . G <*> 0 . DP=29;I16=13,16,0,0,1025,37125,0,0,1623,93581,0,0,471,10053,0,0;QS=3,0;MQSB=0.307929;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,108:4:0 0,15,144:5:0 +X 3963 . C <*> 0 . DP=28;I16=13,15,0,0,1040,39100,0,0,1563,89981,0,0,463,9871,0,0;QS=3,0;MQSB=0.326055;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,111:4:0 0,12,126:4:0 +X 3964 . T <*> 0 . DP=27;I16=12,15,0,0,1036,39928,0,0,1503,86381,0,0,456,9720,0,0;QS=3,0;MQSB=0.273507;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,9,94:3:0 0,12,133:4:0 +X 3965 . G <*> 0 . DP=26;I16=12,14,0,0,993,38165,0,0,1443,82781,0,0,450,9598,0,0;QS=3,0;MQSB=0.29215;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,9,92:3:0 0,12,134:4:0 +X 3966 . A <*> 0 . DP=26;I16=12,13,0,0,930,34834,0,0,1406,81412,0,0,432,9310,0,0;QS=3,0;MQSB=0.520812;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,90:3:0 0,12,140:4:0 +X 3967 . T <*> 0 . DP=26;I16=12,13,0,0,900,32830,0,0,1406,81412,0,0,421,9001,0,0;QS=3,0;MQSB=0.520812;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,9,90:3:0 0,9,100:3:0 +X 3968 . A <*> 0 . DP=25;I16=12,13,0,0,885,31773,0,0,1406,81412,0,0,415,8853,0,0;QS=3,0;MQSB=0.520812;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,9,90:3:0 0,9,99:3:0 +X 3969 . T <*> 0 . DP=24;I16=11,13,0,0,886,32972,0,0,1369,80043,0,0,410,8736,0,0;QS=3,0;MQSB=0.702671;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,85:3:0 0,9,108:3:0 +X 3970 . T <*> 0 . DP=24;I16=11,13,0,0,861,31313,0,0,1369,80043,0,0,405,8649,0,0;QS=3,0;MQSB=0.702671;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,83:3:0 0,9,104:3:0 +X 3971 . C <*> 0 . DP=22;I16=11,11,0,0,815,30625,0,0,1249,72843,0,0,402,8590,0,0;QS=3,0;MQSB=0.751921;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,57:2:0 0,9,103:3:0 +X 3972 . C <*> 0 . DP=22;I16=11,11,0,0,812,30486,0,0,1249,72843,0,0,399,8557,0,0;QS=3,0;MQSB=0.751921;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,55:2:0 0,9,96:3:0 +X 3973 . A <*> 0 . DP=22;I16=11,11,0,0,795,28873,0,0,1249,72843,0,0,395,8501,0,0;QS=3,0;MQSB=0.751921;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,52:2:0 0,9,97:3:0 +X 3974 . C <*> 0 . DP=22;I16=11,11,0,0,729,24447,0,0,1249,72843,0,0,392,8472,0,0;QS=3,0;MQSB=0.751921;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,55:2:0 0,9,78:3:0 +X 3975 . G <*> 0 . DP=22;I16=11,11,0,0,717,24525,0,0,1249,72843,0,0,390,8470,0,0;QS=3,0;MQSB=0.751921;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,46:2:0 0,9,96:3:0 +X 3976 . C <*> 0 . DP=22;I16=11,11,0,0,816,30652,0,0,1249,72843,0,0,387,8445,0,0;QS=3,0;MQSB=0.751921;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,55:2:0 0,9,97:3:0 +X 3977 . A <*> 0 . DP=23;I16=11,11,0,0,740,25384,0,0,1249,72843,0,0,382,8346,0,0;QS=3,0;MQSB=0.751921;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,48:2:0 0,9,90:3:0 +X 3978 . C <*> 0 . DP=23;I16=11,12,0,0,769,26631,0,0,1309,76443,0,0,377,8223,0,0;QS=3,0;MQSB=0.726094;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,47:2:0 0,9,103:3:0 +X 3979 . C <*> 0 . DP=21;I16=9,11,0,0,744,28160,0,0,1152,67874,0,0,361,7905,0,0;QS=3,0;MQSB=0.885207;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,51:2:0 0,9,104:3:0 +X 3980 . T <*> 0 . DP=21;I16=10,11,0,0,756,27872,0,0,1212,71474,0,0,367,7855,0,0;QS=3,0;MQSB=0.914611;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,51:2:0 0,9,98:3:0 +X 3981 . G <*> 0 . DP=21;I16=10,11,0,0,785,29641,0,0,1212,71474,0,0,362,7710,0,0;QS=3,0;MQSB=0.914611;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,50:2:0 0,9,93:3:0 +X 3982 . C <*> 0 . DP=21;I16=10,11,0,0,779,29495,0,0,1212,71474,0,0,357,7591,0,0;QS=3,0;MQSB=0.914611;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,55:2:0 0,9,97:3:0 +X 3983 . T <*> 0 . DP=20;I16=9,11,0,0,720,26274,0,0,1155,68225,0,0,353,7497,0,0;QS=3,0;MQSB=0.993528;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,57:2:0 0,9,93:3:0 +X 3984 . A <*> 0 . DP=21;I16=10,11,0,0,739,26279,0,0,1192,69594,0,0,348,7378,0,0;QS=3,0;MQSB=0.885602;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,53:2:0 0,9,80:3:0 +X 3985 . C <*> 0 . DP=20;I16=10,10,0,0,728,26998,0,0,1132,65994,0,0,344,7234,0,0;QS=3,0;MQSB=0.902256;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,55:2:0 0,9,91:3:0 +X 3986 . A <*> 0 . DP=20;I16=10,10,0,0,685,23815,0,0,1132,65994,0,0,340,7114,0,0;QS=3,0;MQSB=0.902256;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,56:2:0 0,9,84:3:0 +X 3987 . C <*> 0 . DP=20;I16=10,10,0,0,736,28118,0,0,1132,65994,0,0,336,7018,0,0;QS=3,0;MQSB=0.902256;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,55:2:0 0,9,94:3:0 +X 3988 . T <*> 0 . DP=21;I16=10,10,0,0,741,27797,0,0,1132,65994,0,0,332,6946,0,0;QS=3,0;MQSB=0.902256;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,58:2:0 0,9,91:3:0 +X 3989 . C <*> 0 . DP=21;I16=10,11,0,0,729,26185,0,0,1192,69594,0,0,327,6801,0,0;QS=3,0;MQSB=0.885602;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,55:2:0 0,9,88:3:0 +X 3990 . C <*> 0 . DP=21;I16=10,11,0,0,766,28674,0,0,1192,69594,0,0,322,6686,0,0;QS=3,0;MQSB=0.885602;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,55:2:0 0,9,95:3:0 +X 3991 . T <*> 0 . DP=20;I16=9,11,0,0,729,27311,0,0,1132,65994,0,0,318,6600,0,0;QS=3,0;MQSB=0.850154;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,55:2:0 0,9,89:3:0 +X 3992 . T <*> 0 . DP=19;I16=9,10,0,0,667,24173,0,0,1072,62394,0,0,313,6441,0,0;QS=3,0;MQSB=0.868634;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,56:2:0 0,6,72:2:0 +X 3993 . C <*> 0 . DP=18;I16=9,9,0,0,701,27529,0,0,1012,58794,0,0,309,6307,0,0;QS=3,0;MQSB=0.888755;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,59:2:0 0,6,70:2:0 +X 3994 . T <*> 0 . DP=19;I16=10,9,0,0,718,27520,0,0,1049,60163,0,0,305,6197,0,0;QS=3,0;MQSB=0.716531;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,58:2:0 0,6,72:2:0 +X 3995 . T <*> 0 . DP=19;I16=9,9,0,0,641,23025,0,0,989,56563,0,0,277,5487,0,0;QS=3,0;MQSB=0.650623;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,53:2:0 0,6,69:2:0 +X 3996 . A <*> 0 . DP=19;I16=9,9,0,0,665,24815,0,0,989,56563,0,0,274,5428,0,0;QS=3,0;MQSB=0.650623;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,54:2:0 0,6,73:2:0 +X 3997 . G C,<*> 0 . DP=19;I16=10,8,0,1,645,23703,21,441,989,56563,60,3600,287,5843,6,36;QS=2.96023,0.0397727,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.716531;BQB=1;MQ0F=0 PL:DP:DV 0,24,255,42,255,255:15:1 0,6,57,6,57,57:2:0 0,6,60,6,60,60:2:0 +X 3998 . G <*> 0 . DP=18;I16=9,8,0,0,626,23710,0,0,929,52963,0,0,265,5203,0,0;QS=3,0;MQSB=0.687289;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,58:2:0 0,3,36:1:0 +X 3999 . G A,<*> 0 . DP=18;I16=9,7,0,1,596,22974,37,1369,869,49363,60,3600,263,5387,4,16;QS=2.92871,0.0712909,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.687289;BQB=1;MQ0F=0 PL:DP:DV 0,5,255,39,255,255:14:1 0,6,56,6,56,56:2:0 0,3,38,3,38,38:1:0 +X 4000 . C <*> 0 . DP=18;I16=10,8,0,0,669,25389,0,0,989,56563,0,0,283,5753,0,0;QS=3,0;MQSB=0.751866;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,55:2:0 0,3,36:1:0 +X 4001 . T <*> 0 . DP=18;I16=10,8,0,0,680,26006,0,0,989,56563,0,0,279,5727,0,0;QS=3,0;MQSB=0.751866;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,56:2:0 0,3,33:1:0 +X 4002 . G <*> 0 . DP=17;I16=10,7,0,0,621,23281,0,0,929,52963,0,0,276,5724,0,0;QS=2,0;MQSB=0.79189;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,44:2:0 0,0,0:0:0 +X 4003 . A <*> 0 . DP=17;I16=10,7,0,0,597,21507,0,0,929,52963,0,0,272,5692,0,0;QS=2,0;MQSB=0.79189;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,55:2:0 0,0,0:0:0 +X 4004 . T <*> 0 . DP=15;I16=9,6,0,0,527,19031,0,0,849,48963,0,0,270,5678,0,0;QS=2,0;MQSB=0.957526;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,40:1:0 0,0,0:0:0 +X 4005 . A <*> 0 . DP=15;I16=8,5,0,0,479,17731,0,0,729,41763,0,0,237,5195,0,0;QS=2,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,35:1:0 0,0,0:0:0 +X 4006 . T <*> 0 . DP=15;I16=9,6,0,0,554,20776,0,0,849,48963,0,0,266,5698,0,0;QS=2,0;MQSB=0.957526;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,40:1:0 0,0,0:0:0 +X 4007 . T G,<*> 0 . DP=15;I16=9,5,0,1,490,17810,15,225,789,45363,60,3600,245,5371,19,361;QS=1.96746,0.032538,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.957526;BQB=1;MQ0F=0 PL:DP:DV 0,26,255,39,255,255:14:1 0,3,41,3,41,41:1:0 0,0,0,0,0,0:0:0 +X 4008 . C <*> 0 . DP=15;I16=9,6,0,0,488,16890,0,0,849,48963,0,0,262,5782,0,0;QS=2,0;MQSB=0.957526;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,30:1:0 0,0,0:0:0 +X 4009 . C <*> 0 . DP=14;I16=9,5,0,0,524,20150,0,0,794,45938,0,0,261,5847,0,0;QS=2,0;MQSB=0.800737;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,40:1:0 0,0,0:0:0 +X 4010 . A <*> 0 . DP=14;I16=9,5,0,0,523,19731,0,0,794,45938,0,0,259,5875,0,0;QS=2,0;MQSB=0.800737;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,41:1:0 0,0,0:0:0 +X 4011 . C <*> 0 . DP=14;I16=9,5,0,0,489,17613,0,0,794,45938,0,0,257,5915,0,0;QS=2,0;MQSB=0.800737;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,41:1:0 0,0,0:0:0 +X 4012 . A <*> 0 . DP=14;I16=7,5,0,0,365,11867,0,0,674,38738,0,0,223,5293,0,0;QS=2,0;MQSB=0.6821;MQ0F=0 PL:DP:DV 0,33,231:11:0 0,3,30:1:0 0,0,0:0:0 +X 4013 . C <*> 0 . DP=14;I16=8,5,0,0,451,15885,0,0,734,42338,0,0,247,5995,0,0;QS=2,0;MQSB=0.765017;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,37:1:0 0,0,0:0:0 +X 4014 . A <*> 0 . DP=12;I16=8,2,0,0,358,13372,0,0,554,31538,0,0,222,5404,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,213:9:0 0,3,34:1:0 0,0,0:0:0 +X 4015 . C <*> 0 . DP=12;I16=8,2,0,0,350,12812,0,0,554,31538,0,0,222,5442,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,222:9:0 0,3,21:1:0 0,0,0:0:0 +X 4016 . C <*> 0 . DP=12;I16=8,3,0,0,350,11956,0,0,614,35138,0,0,247,6109,0,0;QS=2,0;MQSB=0.829029;MQ0F=0 PL:DP:DV 0,30,215:10:0 0,3,32:1:0 0,0,0:0:0 +X 4017 . C <*> 0 . DP=11;I16=5,2,0,0,227,7765,0,0,374,20738,0,0,173,4279,0,0;QS=2,0;MQSB=0.6;MQ0F=0 PL:DP:DV 0,18,161:6:0 0,3,20:1:0 0,0,0:0:0 +X 4018 . G <*> 0 . DP=11;I16=8,2,0,0,284,8442,0,0,554,31538,0,0,249,6201,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,183:9:0 0,3,17:1:0 0,0,0:0:0 +X 4019 . C <*> 0 . DP=11;I16=9,2,0,0,383,14427,0,0,614,35138,0,0,250,6250,0,0;QS=2,0;MQSB=0.777778;MQ0F=0 PL:DP:DV 0,30,228:10:0 0,3,33:1:0 0,0,0:0:0 +X 4020 . T <*> 0 . DP=10;I16=8,2,0,0,362,13668,0,0,554,31538,0,0,250,6250,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,213:9:0 0,3,38:1:0 0,0,0:0:0 +X 4021 . A <*> 0 . DP=10;I16=8,1,0,0,304,10512,0,0,494,27938,0,0,225,5625,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,177:8:0 0,3,33:1:0 0,0,0:0:0 +X 4022 . C <*> 0 . DP=10;I16=7,2,0,0,310,11582,0,0,494,27938,0,0,225,5625,0,0;QS=2,0;MQSB=0.714286;MQ0F=0 PL:DP:DV 0,24,202:8:0 0,3,36:1:0 0,0,0:0:0 +X 4023 . A <*> 0 . DP=10;I16=8,2,0,0,354,13116,0,0,554,31538,0,0,250,6250,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,209:9:0 0,3,40:1:0 0,0,0:0:0 +X 4024 . C <*> 0 . DP=10;I16=8,2,0,0,361,13669,0,0,554,31538,0,0,250,6250,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,214:9:0 0,3,39:1:0 0,0,0:0:0 +X 4025 . T <*> 0 . DP=10;I16=8,1,0,0,360,14488,0,0,494,27938,0,0,224,5576,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,199:8:0 0,3,42:1:0 0,0,0:0:0 +X 4026 . C <*> 0 . DP=10;I16=8,2,0,0,329,11655,0,0,554,31538,0,0,248,6154,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,192:9:0 0,3,39:1:0 0,0,0:0:0 +X 4027 . C <*> 0 . DP=10;I16=8,2,0,0,380,14888,0,0,554,31538,0,0,246,6060,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,231:9:0 0,3,38:1:0 0,0,0:0:0 +X 4028 . T <*> 0 . DP=10;I16=8,2,0,0,333,12157,0,0,554,31538,0,0,244,5970,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,202:9:0 0,3,41:1:0 0,0,0:0:0 +X 4029 . T <*> 0 . DP=10;I16=8,2,0,0,377,14333,0,0,554,31538,0,0,242,5884,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,225:9:0 0,3,38:1:0 0,0,0:0:0 +X 4030 . C <*> 0 . DP=10;I16=8,2,0,0,348,12558,0,0,554,31538,0,0,240,5802,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,211:9:0 0,3,30:1:0 0,0,0:0:0 +X 4031 . T <*> 0 . DP=10;I16=8,2,0,0,388,15302,0,0,554,31538,0,0,238,5724,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,229:9:0 0,3,39:1:0 0,0,0:0:0 +X 4032 . T <*> 0 . DP=10;I16=8,2,0,0,341,11901,0,0,554,31538,0,0,236,5650,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,204:9:0 0,3,39:1:0 0,0,0:0:0 +X 4033 . A <*> 0 . DP=10;I16=7,2,0,0,299,10717,0,0,494,27938,0,0,218,5324,0,0;QS=2,0;MQSB=0.714286;MQ0F=0 PL:DP:DV 0,24,193:8:0 0,3,38:1:0 0,0,0:0:0 +X 4034 . G <*> 0 . DP=10;I16=8,2,0,0,347,12527,0,0,554,31538,0,0,231,5465,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,211:9:0 0,3,39:1:0 0,0,0:0:0 +X 4035 . G T,<*> 0 . DP=10;I16=7,2,1,0,316,11900,13,169,494,27938,60,3600,202,4682,25,625;QS=1.9547,0.0452962,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.75;BQB=1;MQ0F=0 PL:DP:DV 0,13,195,24,198,200:9:1 0,3,31,3,31,31:1:0 0,0,0,0,0,0:0:0 +X 4036 . G <*> 0 . DP=10;I16=8,1,0,0,269,8839,0,0,494,27938,0,0,198,4532,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,156:8:0 0,3,34:1:0 0,0,0:0:0 +X 4037 . C <*> 0 . DP=10;I16=8,2,0,0,342,12466,0,0,554,31538,0,0,219,5015,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,210:9:0 0,3,30:1:0 0,0,0:0:0 +X 4038 . T <*> 0 . DP=10;I16=8,2,0,0,335,12149,0,0,554,31538,0,0,215,4881,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,203:9:0 0,3,29:1:0 0,0,0:0:0 +X 4039 . G <*> 0 . DP=10;I16=8,1,0,0,302,10798,0,0,494,27938,0,0,186,4130,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,180:8:0 0,3,31:1:0 0,0,0:0:0 +X 4040 . A <*> 0 . DP=10;I16=8,2,0,0,380,14602,0,0,554,31538,0,0,207,4637,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,223:9:0 0,3,41:1:0 0,0,0:0:0 +X 4041 . T <*> 0 . DP=10;I16=8,2,0,0,367,13633,0,0,554,31538,0,0,202,4478,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,216:9:0 0,3,40:1:0 0,0,0:0:0 +X 4042 . A <*> 0 . DP=10;I16=8,2,0,0,337,11657,0,0,554,31538,0,0,197,4329,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,205:9:0 0,3,34:1:0 0,0,0:0:0 +X 4043 . T <*> 0 . DP=10;I16=8,2,0,0,314,10428,0,0,554,31538,0,0,192,4190,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,190:9:0 0,3,35:1:0 0,0,0:0:0 +X 4044 . T <*> 0 . DP=10;I16=8,2,0,0,333,11579,0,0,554,31538,0,0,187,4061,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,199:9:0 0,3,37:1:0 0,0,0:0:0 +X 4045 . C <*> 0 . DP=10;I16=7,2,0,0,291,10099,0,0,494,27938,0,0,176,3906,0,0;QS=1,0;MQSB=0.714286;MQ0F=0 PL:DP:DV 0,27,204:9:0 0,0,0:0:0 0,0,0:0:0 +X 4046 . C <*> 0 . DP=10;I16=8,2,0,0,356,13032,0,0,554,31538,0,0,177,3833,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,212:9:0 0,3,35:1:0 0,0,0:0:0 +X 4047 . A <*> 0 . DP=10;I16=8,2,0,0,347,12557,0,0,554,31538,0,0,172,3734,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,204:9:0 0,3,40:1:0 0,0,0:0:0 +X 4048 . C <*> 0 . DP=10;I16=8,2,0,0,342,12124,0,0,554,31538,0,0,167,3645,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,202:9:0 0,3,37:1:0 0,0,0:0:0 +X 4049 . G <*> 0 . DP=10;I16=7,2,0,0,260,7786,0,0,494,27938,0,0,146,3310,0,0;QS=2,0;MQSB=0.714286;MQ0F=0 PL:DP:DV 0,24,173:8:0 0,3,24:1:0 0,0,0:0:0 +X 4050 . C <*> 0 . DP=9;I16=6,2,0,0,291,10813,0,0,434,24338,0,0,157,3495,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL:DP:DV 0,24,204:8:0 0,0,0:0:0 0,0,0:0:0 +X 4051 . A <*> 0 . DP=8;I16=5,2,0,0,259,9679,0,0,374,20738,0,0,146,3370,0,0;QS=1,0;MQSB=0.6;MQ0F=0 PL:DP:DV 0,21,192:7:0 0,0,0:0:0 0,0,0:0:0 +X 4052 . C <*> 0 . DP=8;I16=5,2,0,0,247,9025,0,0,374,20738,0,0,143,3281,0,0;QS=1,0;MQSB=0.6;MQ0F=0 PL:DP:DV 0,21,190:7:0 0,0,0:0:0 0,0,0:0:0 +X 4053 . C <*> 0 . DP=8;I16=6,2,0,0,254,9000,0,0,434,24338,0,0,146,3234,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL:DP:DV 0,24,184:8:0 0,0,0:0:0 0,0,0:0:0 +X 4054 . C <*> 0 . DP=8;I16=3,2,0,0,160,5344,0,0,254,13538,0,0,122,2984,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,134:5:0 0,0,0:0:0 0,0,0:0:0 +X 4055 . G <*> 0 . DP=8;I16=6,2,0,0,230,6982,0,0,434,24338,0,0,138,3066,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL:DP:DV 0,24,169:8:0 0,0,0:0:0 0,0,0:0:0 +X 4056 . C <*> 0 . DP=8;I16=6,2,0,0,275,10153,0,0,434,24338,0,0,134,2994,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL:DP:DV 0,24,197:8:0 0,0,0:0:0 0,0,0:0:0 +X 4057 . T <*> 0 . DP=8;I16=5,2,0,0,243,8603,0,0,374,20738,0,0,127,2877,0,0;QS=1,0;MQSB=0.6;MQ0F=0 PL:DP:DV 0,21,182:7:0 0,0,0:0:0 0,0,0:0:0 +X 4058 . A <*> 0 . DP=7;I16=4,2,0,0,214,7742,0,0,314,17138,0,0,116,2728,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,171:6:0 0,0,0:0:0 0,0,0:0:0 +X 4059 . C <*> 0 . DP=6;I16=4,2,0,0,204,7164,0,0,314,17138,0,0,119,2635,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,168:6:0 0,0,0:0:0 0,0,0:0:0 +X 4060 . A <*> 0 . DP=6;I16=4,2,0,0,227,8683,0,0,314,17138,0,0,115,2501,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,177:6:0 0,0,0:0:0 0,0,0:0:0 +X 4061 . C <*> 0 . DP=6;I16=4,2,0,0,193,6681,0,0,314,17138,0,0,111,2375,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,157:6:0 0,0,0:0:0 0,0,0:0:0 +X 4062 . T <*> 0 . DP=6;I16=4,1,0,0,195,7621,0,0,254,13538,0,0,82,1632,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,151:5:0 0,0,0:0:0 0,0,0:0:0 +X 4063 . C <*> 0 . DP=6;I16=4,2,0,0,216,7984,0,0,314,17138,0,0,102,2098,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,170:6:0 0,0,0:0:0 0,0,0:0:0 +X 4064 . C <*> 0 . DP=6;I16=4,2,0,0,227,8747,0,0,314,17138,0,0,97,1949,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,177:6:0 0,0,0:0:0 0,0,0:0:0 +X 4065 . T <*> 0 . DP=6;I16=4,2,0,0,202,6880,0,0,314,17138,0,0,92,1810,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,161:6:0 0,0,0:0:0 0,0,0:0:0 +X 4066 . T <*> 0 . DP=5;I16=3,2,0,0,180,6554,0,0,254,13538,0,0,88,1680,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,153:5:0 0,0,0:0:0 0,0,0:0:0 +X 4067 . C <*> 0 . DP=5;I16=3,2,0,0,181,6637,0,0,254,13538,0,0,84,1558,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,153:5:0 0,0,0:0:0 0,0,0:0:0 +X 4068 . T <*> 0 . DP=5;I16=3,2,0,0,198,7868,0,0,254,13538,0,0,80,1444,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,164:5:0 0,0,0:0:0 0,0,0:0:0 +X 4069 . T <*> 0 . DP=5;I16=3,2,0,0,177,6325,0,0,254,13538,0,0,76,1338,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,154:5:0 0,0,0:0:0 0,0,0:0:0 +X 4070 . A <*> 0 . DP=5;I16=3,2,0,0,161,5263,0,0,254,13538,0,0,72,1240,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,140:5:0 0,0,0:0:0 0,0,0:0:0 +X 4071 . G <*> 0 . DP=5;I16=3,2,0,0,166,5658,0,0,254,13538,0,0,68,1150,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,142:5:0 0,0,0:0:0 0,0,0:0:0 +X 4072 . G <*> 0 . DP=5;I16=2,2,0,0,138,4974,0,0,194,9938,0,0,55,987,0,0;QS=1,0;MQSB=0;MQ0F=0 PL:DP:DV 0,12,122:4:0 0,0,0:0:0 0,0,0:0:0 +X 4073 . G <*> 0 . DP=5;I16=3,2,0,0,156,5082,0,0,254,13538,0,0,60,994,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,136:5:0 0,0,0:0:0 0,0,0:0:0 +X 4074 . C <*> 0 . DP=5;I16=3,2,0,0,160,5602,0,0,254,13538,0,0,56,928,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,142:5:0 0,0,0:0:0 0,0,0:0:0 +X 4075 . T <*> 0 . DP=5;I16=3,2,0,0,187,7069,0,0,254,13538,0,0,52,870,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,155:5:0 0,0,0:0:0 0,0,0:0:0 +X 4076 . G <*> 0 . DP=5;I16=3,2,0,0,174,6298,0,0,254,13538,0,0,48,820,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,149:5:0 0,0,0:0:0 0,0,0:0:0 +X 4077 . A <*> 0 . DP=4;I16=3,1,0,0,138,4810,0,0,194,9938,0,0,44,728,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,12,121:4:0 0,0,0:0:0 0,0,0:0:0 +X 4078 . T <*> 0 . DP=4;I16=3,1,0,0,143,5173,0,0,194,9938,0,0,40,644,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,12,124:4:0 0,0,0:0:0 0,0,0:0:0 +X 4079 . A <*> 0 . DP=4;I16=3,1,0,0,121,3847,0,0,194,9938,0,0,36,568,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,12,107:4:0 0,0,0:0:0 0,0,0:0:0 +X 4080 . T <*> 0 . DP=4;I16=3,0,0,0,106,3778,0,0,134,6338,0,0,25,451,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,9,87:3:0 0,0,0:0:0 0,0,0:0:0 +X 4081 . T <*> 0 . DP=4;I16=3,1,0,0,106,2934,0,0,194,9938,0,0,28,440,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,12,94:4:0 0,0,0:0:0 0,0,0:0:0 +X 4082 . C <*> 0 . DP=3;I16=2,1,0,0,110,4042,0,0,134,6338,0,0,25,387,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,9,103:3:0 0,0,0:0:0 0,0,0:0:0 +X 4083 . C <*> 0 . DP=3;I16=2,1,0,0,104,3648,0,0,134,6338,0,0,22,340,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,9,98:3:0 0,0,0:0:0 0,0,0:0:0 +X 4084 . A <*> 0 . DP=2;I16=1,1,0,0,78,3050,0,0,97,4969,0,0,20,298,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,6,74:2:0 0,0,0:0:0 0,0,0:0:0 +X 4085 . C <*> 0 . DP=2;I16=1,1,0,0,62,1940,0,0,97,4969,0,0,18,260,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,6,62:2:0 0,0,0:0:0 0,0,0:0:0 +X 4086 . G <*> 0 . DP=2;I16=1,1,0,0,56,1640,0,0,97,4969,0,0,16,226,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,6,56:2:0 0,0,0:0:0 0,0,0:0:0 +X 4087 . C <*> 0 . DP=2;I16=1,1,0,0,69,2405,0,0,97,4969,0,0,14,196,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,6,68:2:0 0,0,0:0:0 0,0,0:0:0 +X 4088 . A <*> 0 . DP=1;I16=1,0,0,0,39,1521,0,0,37,1369,0,0,13,169,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,37:1:0 0,0,0:0:0 0,0,0:0:0 +X 4089 . C <*> 0 . DP=1;I16=1,0,0,0,36,1296,0,0,37,1369,0,0,12,144,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,36:1:0 0,0,0:0:0 0,0,0:0:0 +X 4090 . C <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,37,1369,0,0,11,121,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,33:1:0 0,0,0:0:0 0,0,0:0:0 +X 4091 . T <*> 0 . DP=1;I16=1,0,0,0,36,1296,0,0,37,1369,0,0,10,100,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,36:1:0 0,0,0:0:0 0,0,0:0:0 +X 4092 . G <*> 0 . DP=1;I16=1,0,0,0,37,1369,0,0,37,1369,0,0,9,81,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,37:1:0 0,0,0:0:0 0,0,0:0:0 +X 4093 . C <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,37,1369,0,0,8,64,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,35:1:0 0,0,0:0:0 0,0,0:0:0 +X 4094 . T <*> 0 . DP=1;I16=1,0,0,0,40,1600,0,0,37,1369,0,0,7,49,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,37:1:0 0,0,0:0:0 0,0,0:0:0 +X 4095 . A <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,37,1369,0,0,6,36,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,35:1:0 0,0,0:0:0 0,0,0:0:0 +X 4096 . C <*> 0 . DP=1;I16=1,0,0,0,32,1024,0,0,37,1369,0,0,5,25,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,32:1:0 0,0,0:0:0 0,0,0:0:0 +X 4097 . A <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,37,1369,0,0,4,16,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,35:1:0 0,0,0:0:0 0,0,0:0:0 +X 4098 . C <*> 0 . DP=1;I16=1,0,0,0,31,961,0,0,37,1369,0,0,3,9,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,31:1:0 0,0,0:0:0 0,0,0:0:0 +X 4099 . T <*> 0 . DP=1;I16=1,0,0,0,32,1024,0,0,37,1369,0,0,2,4,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,32:1:0 0,0,0:0:0 0,0,0:0:0 +X 4100 . C <*> 0 . DP=1;I16=1,0,0,0,27,729,0,0,37,1369,0,0,1,1,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,27:1:0 0,0,0:0:0 0,0,0:0:0 +X 4101 . C <*> 0 . DP=1;I16=1,0,0,0,26,676,0,0,37,1369,0,0,0,0,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,26:1:0 0,0,0:0:0 0,0,0:0:0 diff --git a/test/mpileup.c.1.out b/test/mpileup.c.1.out new file mode 100644 index 0000000..1c4a0c8 --- /dev/null +++ b/test/mpileup.c.1.out @@ -0,0 +1,43 @@ +##fileformat=VCFv4.2 +##FILTER= +##samtoolsVersion=1.1-19-g6b249e2+htslib-1.1-74-g845c515 +##samtoolsCommand=samtools mpileup -uvDV -b xxx//mpileup.bam.list -f xxx//mpileup.ref.fa.gz +##reference=file://xxx//mpileup.ref.fa.gz +##contig= +##ALT= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT HG00100 HG00101 HG00102 +17 302 . T TA 999 . INDEL;IDV=7;IMF=1;DP=25;VDB=0.27613;SGB=-4.22417;MQSB=0.0443614;MQ0F=0;AF1=0.685575;AC1=4;DP4=2,4,8,11;MQ=51;FQ=61.4911;PV4=1,1,1,1 GT:PL:DP:DV 0/1:167,0,96:11:6 0/1:157,0,9:7:6 1/1:201,21,0:7:7 +17 828 . T C 999 . DP=25;VDB=0.842082;SGB=-4.20907;RPB=0.950652;MQB=1;MQSB=1;BQB=0.929717;MQ0F=0;AF1=0.656389;AC1=4;DP4=2,4,8,11;MQ=60;FQ=89.3748;PV4=1,1,1,0.32233 GT:PL:DP:DV 0/1:211,0,35:12:10 0/1:116,0,91:9:5 1/1:120,12,0:4:4 +17 834 . G A 999 . DP=25;VDB=0.788006;SGB=-4.01214;RPB=0.999233;MQB=1;MQSB=1;BQB=0.821668;MQ0F=0;AF1=0.646503;AC1=4;DP4=2,3,7,10;MQ=60;FQ=68.6952;PV4=1,1,1,0.228905 GT:PL:DP:DV 0/1:185,0,46:11:9 0/1:128,0,59:8:5 1/1:89,9,0:3:3 +17 1665 . T C 3.14059 . DP=20;VDB=0.1;SGB=0.346553;RPB=0.222222;MQB=0.611111;MQSB=0.988166;BQB=0.944444;MQ0F=0;AF1=0.167199;AC1=1;DP4=7,11,1,1;MQ=56;FQ=3.56819;PV4=1,0.239991,0.0798553,0.27333 GT:PL:DP:DV 0/0:0,21,185:7:0 0/0:0,27,222:9:0 0/1:35,0,51:4:2 +17 1869 . A T 134.348 . DP=24;VDB=0.928022;SGB=-11.9537;RPB=0.984127;MQB=0.96464;MQSB=0.931547;BQB=0.359155;MQ0F=0;AF1=0.598209;AC1=4;DP4=6,9,5,4;MQ=59;FQ=138.299;PV4=0.675175,0.0234896,1,0.324361 GT:PL:DP:DV 0/1:115,0,224:18:7 0/1:16,0,104:5:1 1/1:42,3,0:1:1 +17 2041 . G A 999 . DP=31;VDB=0.816435;SGB=-4.18892;RPB=0.88473;MQB=0.972375;MQSB=0.968257;BQB=0.311275;MQ0F=0;AF1=0.665982;AC1=4;DP4=6,5,12,7;MQ=59;FQ=999;PV4=0.71163,1,0.228209,0.143795 GT:PL:DP:DV 0/1:229,0,212:21:11 0/1:32,0,24:2:1 1/1:223,21,0:7:7 +17 2220 . G A 999 . DP=21;VDB=0.532753;SGB=-3.51597;RPB=0.964198;MQB=0.898397;MQSB=0.875769;BQB=0.0354359;MQ0F=0;AF1=0.656341;AC1=4;DP4=6,2,1,11;MQ=59;FQ=139.373;PV4=0.00443756,1,1,1 GT:PL:DP:DV 0/1:139,0,130:12:6 0/1:69,0,46:4:2 1/1:131,12,0:4:4 +17 2564 . A G 227.769 . DP=15;VDB=0.690812;SGB=-3.20711;RPB=0.197899;MQB=1;MQSB=1;BQB=0.965069;MQ0F=0;AF1=0.656337;AC1=4;DP4=1,4,4,5;MQ=60;FQ=97.3723;PV4=0.58042,1,1,1 GT:PL:DP:DV 0/1:88,0,78:6:3 0/1:57,0,56:4:2 1/1:124,12,0:4:4 +17 3104 . C T 24.364 . DP=25;VDB=0.8;SGB=0.346553;RPB=0.717391;MQB=0.956522;MQSB=0.962269;BQB=0.978261;MQ0F=0;AF1=0.170892;AC1=1;DP4=8,15,2,0;MQ=59;FQ=25.179;PV4=0.15,1,1,1 GT:PL:DP:DV 0/0:0,48,255:16:0 0/0:0,12,144:4:0 0/1:59,0,93:5:2 +17 3587 . G A 353.302 . DP=29;VDB=0.902044;SGB=-3.91326;RPB=0.800999;MQB=1;MQSB=1;BQB=0.156944;MQ0F=0;AF1=0.665739;AC1=4;DP4=4,7,10,6;MQ=60;FQ=358.057;PV4=0.25186,0.0986321,1,1 GT:PL:DP:DV 0/1:161,0,184:14:7 0/1:22,0,118:5:1 1/1:212,24,0:8:8 +17 3936 . A G 999 . DP=37;VDB=0.0574114;SGB=-4.60123;RPB=0.741697;MQB=0.812605;MQSB=0.143788;BQB=0.883831;MQ0F=0;AF1=0.666004;AC1=4;DP4=5,6,6,17;MQ=57;FQ=999;PV4=0.434446,0.125787,1,1 GT:PL:DP:DV 0/1:233,0,206:20:11 0/1:77,0,58:6:4 1/1:196,24,0:8:8 diff --git a/test/mpileup.c.X.2.out b/test/mpileup.c.X.2.out new file mode 100644 index 0000000..25022d9 --- /dev/null +++ b/test/mpileup.c.X.2.out @@ -0,0 +1,43 @@ +##fileformat=VCFv4.2 +##FILTER= +##samtoolsVersion=1.1-19-g6b249e2+htslib-1.1-74-g845c515 +##samtoolsCommand=samtools mpileup -uvDV -b xxx//mpileup.bam.list -f xxx//mpileup.ref.fa.gz +##reference=file://xxx//mpileup.ref.fa.gz +##contig= +##ALT= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT HG00100 HG00101 HG00102 +X 302 . T TA 999 . INDEL;IDV=7;IMF=1;DP=25;VDB=0.27613;SGB=-4.22417;MQSB=0.0443614;MQ0F=0;AF1=0.685575;AC1=4;DP4=2,4,8,11;MQ=51;FQ=61.4911;PV4=1,1,1,1 GT:PL:DP:DV 0/1:167,0,96:11:6 0:157,0,9:7:6 1/1:201,21,0:7:7 +X 828 . T C 999 . DP=25;VDB=0.842082;SGB=-4.20907;RPB=0.950652;MQB=1;MQSB=1;BQB=0.929717;MQ0F=0;AF1=0.656389;AC1=4;DP4=2,4,8,11;MQ=60;FQ=89.3748;PV4=1,1,1,0.32233 GT:PL:DP:DV 0/1:211,0,35:12:10 0:116,91:9:5 1/1:120,12,0:4:4 +X 834 . G A 999 . DP=25;VDB=0.788006;SGB=-4.01214;RPB=0.999233;MQB=1;MQSB=1;BQB=0.821668;MQ0F=0;AF1=0.646503;AC1=4;DP4=2,3,7,10;MQ=60;FQ=68.6952;PV4=1,1,1,0.228905 GT:PL:DP:DV 0/1:185,0,46:11:9 0:128,59:8:5 1/1:89,9,0:3:3 +X 1665 . T C 3.14059 . DP=20;VDB=0.1;SGB=0.346553;RPB=0.222222;MQB=0.611111;MQSB=0.988166;BQB=0.944444;MQ0F=0;AF1=0.167199;AC1=1;DP4=7,11,1,1;MQ=56;FQ=3.56819;PV4=1,0.239991,0.0798553,0.27333 GT:PL:DP:DV 0/0:0,21,185:7:0 0:0,222:9:0 0/1:35,0,51:4:2 +X 1869 . A T 134.348 . DP=24;VDB=0.928022;SGB=-11.9537;RPB=0.984127;MQB=0.96464;MQSB=0.931547;BQB=0.359155;MQ0F=0;AF1=0.598209;AC1=4;DP4=6,9,5,4;MQ=59;FQ=138.299;PV4=0.675175,0.0234896,1,0.324361 GT:PL:DP:DV 0/1:115,0,224:18:7 0:16,104:5:1 1/1:42,3,0:1:1 +X 2041 . G A 999 . DP=31;VDB=0.816435;SGB=-4.18892;RPB=0.88473;MQB=0.972375;MQSB=0.968257;BQB=0.311275;MQ0F=0;AF1=0.665982;AC1=4;DP4=6,5,12,7;MQ=59;FQ=999;PV4=0.71163,1,0.228209,0.143795 GT:PL:DP:DV 0/1:229,0,212:21:11 0:32,24:2:1 1/1:223,21,0:7:7 +X 2220 . G A 999 . DP=21;VDB=0.532753;SGB=-3.51597;RPB=0.964198;MQB=0.898397;MQSB=0.875769;BQB=0.0354359;MQ0F=0;AF1=0.656341;AC1=4;DP4=6,2,1,11;MQ=59;FQ=139.373;PV4=0.00443756,1,1,1 GT:PL:DP:DV 0/1:139,0,130:12:6 0:69,46:4:2 1/1:131,12,0:4:4 +X 2564 . A G 227.769 . DP=15;VDB=0.690812;SGB=-3.20711;RPB=0.197899;MQB=1;MQSB=1;BQB=0.965069;MQ0F=0;AF1=0.656337;AC1=4;DP4=1,4,4,5;MQ=60;FQ=97.3723;PV4=0.58042,1,1,1 GT:PL:DP:DV 0/1:88,0,78:6:3 0:57,56:4:2 1/1:124,12,0:4:4 +X 3104 . C T 24.364 . DP=25;VDB=0.8;SGB=0.346553;RPB=0.717391;MQB=0.956522;MQSB=0.962269;BQB=0.978261;MQ0F=0;AF1=0.170892;AC1=1;DP4=8,15,2,0;MQ=59;FQ=25.179;PV4=0.15,1,1,1 GT:PL:DP:DV 0/0:0,48,255:16:0 0:0,144:4:0 0/1:59,0,93:5:2 +X 3587 . G A 353.302 . DP=29;VDB=0.902044;SGB=-3.91326;RPB=0.800999;MQB=1;MQSB=1;BQB=0.156944;MQ0F=0;AF1=0.665739;AC1=4;DP4=4,7,10,6;MQ=60;FQ=358.057;PV4=0.25186,0.0986321,1,1 GT:PL:DP:DV 0/1:161,0,184:14:7 0:22,118:5:1 1/1:212,24,0:8:8 +X 3936 . A G 999 . DP=37;VDB=0.0574114;SGB=-4.60123;RPB=0.741697;MQB=0.812605;MQSB=0.143788;BQB=0.883831;MQ0F=0;AF1=0.666004;AC1=4;DP4=5,6,6,17;MQ=57;FQ=999;PV4=0.434446,0.125787,1,1 GT:PL:DP:DV 0/1:233,0,206:20:11 0:77,58:6:4 1/1:196,24,0:8:8 diff --git a/test/mpileup.c.X.out b/test/mpileup.c.X.out new file mode 100644 index 0000000..e35b12b --- /dev/null +++ b/test/mpileup.c.X.out @@ -0,0 +1,43 @@ +##fileformat=VCFv4.2 +##FILTER= +##samtoolsVersion=1.1-19-g6b249e2+htslib-1.1-74-g845c515 +##samtoolsCommand=samtools mpileup -uvDV -b xxx//mpileup.bam.list -f xxx//mpileup.ref.fa.gz +##reference=file://xxx//mpileup.ref.fa.gz +##contig= +##ALT= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT HG00100 HG00101 HG00102 +X 302 . T TA 999 . INDEL;IDV=7;IMF=1;DP=25;VDB=0.27613;SGB=-4.22417;MQSB=0.0443614;MQ0F=0;AF1=0.685575;AC1=4;DP4=2,4,8,11;MQ=51;FQ=61.4911;PV4=1,1,1,1 GT:PL:DP:DV 0/1:167,0,96:11:6 0:157,0,9:7:6 1/1:201,21,0:7:7 +X 828 . T C 999 . DP=25;VDB=0.842082;SGB=-4.20907;RPB=0.950652;MQB=1;MQSB=1;BQB=0.929717;MQ0F=0;AF1=0.656389;AC1=4;DP4=2,4,8,11;MQ=60;FQ=89.3748;PV4=1,1,1,0.32233 GT:PL:DP:DV 0/1:211,0,35:12:10 0:116,91:9:5 1/1:120,12,0:4:4 +X 834 . G A 999 . DP=25;VDB=0.788006;SGB=-4.01214;RPB=0.999233;MQB=1;MQSB=1;BQB=0.821668;MQ0F=0;AF1=0.646503;AC1=4;DP4=2,3,7,10;MQ=60;FQ=68.6952;PV4=1,1,1,0.228905 GT:PL:DP:DV 0/1:185,0,46:11:9 0:128,59:8:5 1/1:89,9,0:3:3 +X 1665 . T C 3.14059 . DP=20;VDB=0.1;SGB=0.346553;RPB=0.222222;MQB=0.611111;MQSB=0.988166;BQB=0.944444;MQ0F=0;AF1=0.167199;AC1=1;DP4=7,11,1,1;MQ=56;FQ=3.56819;PV4=1,0.239991,0.0798553,0.27333 GT:PL:DP:DV 0/0:0,21,185:7:0 0/0:0,27,222:9:0 0/1:35,0,51:4:2 +X 1869 . A T 134.348 . DP=24;VDB=0.928022;SGB=-11.9537;RPB=0.984127;MQB=0.96464;MQSB=0.931547;BQB=0.359155;MQ0F=0;AF1=0.598209;AC1=4;DP4=6,9,5,4;MQ=59;FQ=138.299;PV4=0.675175,0.0234896,1,0.324361 GT:PL:DP:DV 0/1:115,0,224:18:7 0/1:16,0,104:5:1 1/1:42,3,0:1:1 +X 2041 . G A 999 . DP=31;VDB=0.816435;SGB=-4.18892;RPB=0.88473;MQB=0.972375;MQSB=0.968257;BQB=0.311275;MQ0F=0;AF1=0.665982;AC1=4;DP4=6,5,12,7;MQ=59;FQ=999;PV4=0.71163,1,0.228209,0.143795 GT:PL:DP:DV 0/1:229,0,212:21:11 0/1:32,0,24:2:1 1/1:223,21,0:7:7 +X 2220 . G A 999 . DP=21;VDB=0.532753;SGB=-3.51597;RPB=0.964198;MQB=0.898397;MQSB=0.875769;BQB=0.0354359;MQ0F=0;AF1=0.656341;AC1=4;DP4=6,2,1,11;MQ=59;FQ=139.373;PV4=0.00443756,1,1,1 GT:PL:DP:DV 0/1:139,0,130:12:6 0/1:69,0,46:4:2 1/1:131,12,0:4:4 +X 2564 . A G 227.769 . DP=15;VDB=0.690812;SGB=-3.20711;RPB=0.197899;MQB=1;MQSB=1;BQB=0.965069;MQ0F=0;AF1=0.656337;AC1=4;DP4=1,4,4,5;MQ=60;FQ=97.3723;PV4=0.58042,1,1,1 GT:PL:DP:DV 0/1:88,0,78:6:3 0/1:57,0,56:4:2 1/1:124,12,0:4:4 +X 3104 . C T 24.364 . DP=25;VDB=0.8;SGB=0.346553;RPB=0.717391;MQB=0.956522;MQSB=0.962269;BQB=0.978261;MQ0F=0;AF1=0.170892;AC1=1;DP4=8,15,2,0;MQ=59;FQ=25.179;PV4=0.15,1,1,1 GT:PL:DP:DV 0/0:0,48,255:16:0 0:0,144:4:0 0/1:59,0,93:5:2 +X 3587 . G A 353.302 . DP=29;VDB=0.902044;SGB=-3.91326;RPB=0.800999;MQB=1;MQSB=1;BQB=0.156944;MQ0F=0;AF1=0.665739;AC1=4;DP4=4,7,10,6;MQ=60;FQ=358.057;PV4=0.25186,0.0986321,1,1 GT:PL:DP:DV 0/1:161,0,184:14:7 0:22,118:5:1 1/1:212,24,0:8:8 +X 3936 . A G 999 . DP=37;VDB=0.0574114;SGB=-4.60123;RPB=0.741697;MQB=0.812605;MQSB=0.143788;BQB=0.883831;MQ0F=0;AF1=0.666004;AC1=4;DP4=5,6,6,17;MQ=57;FQ=999;PV4=0.434446,0.125787,1,1 GT:PL:DP:DV 0/1:233,0,206:20:11 0:77,58:6:4 1/1:196,24,0:8:8 diff --git a/test/mpileup.c.X.vcf b/test/mpileup.c.X.vcf new file mode 100644 index 0000000..ea2983a --- /dev/null +++ b/test/mpileup.c.X.vcf @@ -0,0 +1,4127 @@ +##fileformat=VCFv4.2 +##FILTER= +##samtoolsVersion=1.1-19-g6b249e2+htslib-1.1-74-g845c515 +##samtoolsCommand=samtools mpileup -uvDV -b xxx//mpileup.bam.list -f xxx//mpileup.ref.fa.gz +##reference=file://xxx//mpileup.ref.fa.gz +##contig= +##ALT= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT HG00100 HG00101 HG00102 +X 1 . A <*> 0 . DP=11;I16=11,0,0,0,452,18594,0,0,319,9251,0,0,223,4959,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 +X 2 . A <*> 0 . DP=11;I16=11,0,0,0,439,17587,0,0,319,9251,0,0,226,5030,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 +X 3 . G <*> 0 . DP=11;I16=11,0,0,0,431,16971,0,0,319,9251,0,0,229,5111,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 +X 4 . C <*> 0 . DP=11;I16=11,0,0,0,423,16417,0,0,319,9251,0,0,232,5202,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,71:3:0 +X 5 . T <*> 0 . DP=11;I16=11,0,0,0,450,18520,0,0,319,9251,0,0,234,5252,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 +X 6 . T <*> 0 . DP=11;I16=11,0,0,0,403,14847,0,0,319,9251,0,0,236,5310,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 +X 7 . C <*> 0 . DP=11;I16=11,0,0,0,446,18114,0,0,319,9251,0,0,237,5327,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 +X 8 . T <*> 0 . DP=11;I16=11,0,0,0,465,19677,0,0,319,9251,0,0,238,5354,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 +X 9 . C <*> 0 . DP=11;I16=11,0,0,0,447,18205,0,0,319,9251,0,0,239,5391,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 +X 10 . A <*> 0 . DP=11;I16=11,0,0,0,426,16756,0,0,319,9251,0,0,240,5438,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,69:3:0 +X 11 . C <*> 0 . DP=11;I16=11,0,0,0,413,15603,0,0,319,9251,0,0,241,5495,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 +X 12 . C <*> 0 . DP=11;I16=11,0,0,0,438,17506,0,0,319,9251,0,0,242,5562,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 +X 13 . C <*> 0 . DP=11;I16=11,0,0,0,437,17463,0,0,319,9251,0,0,243,5639,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 +X 14 . T <*> 0 . DP=11;I16=11,0,0,0,453,18715,0,0,319,9251,0,0,242,5628,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 +X 15 . G <*> 0 . DP=11;I16=11,0,0,0,439,17599,0,0,319,9251,0,0,240,5580,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 +X 16 . T <*> 0 . DP=11;I16=11,0,0,0,426,16546,0,0,319,9251,0,0,238,5544,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 +X 17 . T <*> 0 . DP=11;I16=11,0,0,0,407,15195,0,0,319,9251,0,0,235,5469,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 +X 18 . C <*> 0 . DP=12;I16=12,0,0,0,450,17136,0,0,379,12851,0,0,231,5353,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,113:6:0 0,9,72:3:0 0,9,72:3:0 +X 19 . C <*> 0 . DP=13;I16=13,0,0,0,502,19652,0,0,439,16451,0,0,228,5246,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,112:6:0 0,12,89:4:0 0,9,72:3:0 +X 20 . T <*> 0 . DP=13;I16=13,0,0,0,532,21878,0,0,439,16451,0,0,226,5150,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,116:6:0 0,12,98:4:0 0,9,72:3:0 +X 21 . G <*> 0 . DP=13;I16=13,0,0,0,498,19254,0,0,439,16451,0,0,224,5066,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,117:6:0 0,12,94:4:0 0,9,72:3:0 +X 22 . C <*> 0 . DP=13;I16=13,0,0,0,511,20289,0,0,470,19210,0,0,223,4993,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,115:6:0 0,12,91:4:0 0,9,76:3:0 +X 23 . A <*> 0 . DP=14;I16=14,0,0,0,513,19399,0,0,530,22810,0,0,223,4931,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,133:7:0 0,12,82:4:0 0,9,82:3:0 +X 24 . T <*> 0 . DP=14;I16=14,0,0,0,534,20540,0,0,530,22810,0,0,224,4882,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,131:7:0 0,12,96:4:0 0,9,80:3:0 +X 25 . A <*> 0 . DP=15;I16=15,0,0,0,561,21133,0,0,590,26410,0,0,225,4847,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,140:8:0 0,12,96:4:0 0,9,81:3:0 +X 26 . G <*> 0 . DP=15;I16=15,0,0,0,591,23429,0,0,590,26410,0,0,227,4827,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,151:8:0 0,12,96:4:0 0,9,81:3:0 +X 27 . A <*> 0 . DP=15;I16=15,0,0,0,588,23120,0,0,590,26410,0,0,229,4823,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,146:8:0 0,12,98:4:0 0,9,83:3:0 +X 28 . T <*> 0 . DP=16;I16=16,0,0,0,605,23001,0,0,650,30010,0,0,231,4835,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,147:8:0 0,12,97:4:0 0,12,101:4:0 +X 29 . A <*> 0 . DP=17;I16=17,0,0,0,615,22533,0,0,710,33610,0,0,234,4864,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,146:8:0 0,15,102:5:0 0,12,104:4:0 +X 30 . A <*> 0 . DP=17;I16=17,0,0,0,660,25914,0,0,710,33610,0,0,238,4912,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,149:8:0 0,15,115:5:0 0,12,108:4:0 +X 31 . T <*> 0 . DP=17;I16=17,0,0,0,656,25392,0,0,710,33610,0,0,242,4980,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,150:8:0 0,15,113:5:0 0,12,105:4:0 +X 32 . T <*> 0 . DP=17;I16=17,0,0,0,605,21789,0,0,741,36369,0,0,247,5067,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,143:8:0 0,15,104:5:0 0,12,104:4:0 +X 33 . G <*> 0 . DP=17;I16=17,0,0,0,659,25757,0,0,741,36369,0,0,252,5124,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,158:8:0 0,15,118:5:0 0,12,105:4:0 +X 34 . C <*> 0 . DP=17;I16=17,0,0,0,658,25704,0,0,741,36369,0,0,257,5203,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,151:8:0 0,15,121:5:0 0,12,106:4:0 +X 35 . A <*> 0 . DP=18;I16=18,0,0,0,677,25881,0,0,801,39969,0,0,262,5304,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,152:8:0 0,15,109:5:0 0,15,121:5:0 +X 36 . T <*> 0 . DP=18;I16=18,0,0,0,678,25796,0,0,801,39969,0,0,268,5428,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,151:8:0 0,15,114:5:0 0,15,125:5:0 +X 37 . G <*> 0 . DP=18;I16=18,0,0,0,685,26291,0,0,801,39969,0,0,274,5576,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,157:8:0 0,15,116:5:0 0,15,126:5:0 +X 38 . A <*> 0 . DP=18;I16=18,0,0,0,697,27245,0,0,801,39969,0,0,280,5748,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,152:8:0 0,15,116:5:0 0,15,129:5:0 +X 39 . C <*> 0 . DP=16;I16=16,0,0,0,591,22311,0,0,743,38287,0,0,288,5942,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,148:7:0 0,12,94:4:0 0,15,123:5:0 +X 40 . A <*> 0 . DP=16;I16=16,0,0,0,630,24896,0,0,743,38287,0,0,295,6107,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,146:7:0 0,12,104:4:0 0,15,127:5:0 +X 41 . A <*> 0 . DP=17;I16=17,0,0,0,645,24685,0,0,803,41887,0,0,302,6294,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,151:8:0 0,12,104:4:0 0,15,131:5:0 +X 42 . T <*> 0 . DP=17;I16=17,0,0,0,618,23118,0,0,803,41887,0,0,310,6504,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,155:8:0 0,12,82:4:0 0,15,127:5:0 +X 43 . T <*> 0 . DP=17;I16=17,0,0,0,631,23689,0,0,803,41887,0,0,318,6738,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,151:8:0 0,12,101:4:0 0,15,129:5:0 +X 44 . G <*> 0 . DP=17;I16=17,0,0,0,664,26162,0,0,803,41887,0,0,324,6896,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,164:8:0 0,12,100:4:0 0,15,129:5:0 +X 45 . C <*> 0 . DP=17;I16=17,0,0,0,657,25525,0,0,803,41887,0,0,329,7027,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,163:8:0 0,12,108:4:0 0,15,125:5:0 +X 46 . C <*> 0 . DP=17;I16=17,0,0,0,646,25244,0,0,803,41887,0,0,334,7180,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,161:8:0 0,12,98:4:0 0,15,131:5:0 +X 47 . T <*> 0 . DP=17;I16=17,0,0,0,700,28998,0,0,803,41887,0,0,339,7355,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,165:8:0 0,12,110:4:0 0,15,136:5:0 +X 48 . T <*> 0 . DP=17;I16=17,0,0,0,648,25020,0,0,803,41887,0,0,343,7501,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,155:8:0 0,12,105:4:0 0,15,131:5:0 +X 49 . G <*> 0 . DP=18;I16=18,0,0,0,686,26674,0,0,832,42728,0,0,346,7616,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,158:8:0 0,15,119:5:0 0,15,128:5:0 +X 50 . T <*> 0 . DP=18;I16=17,0,0,0,650,24972,0,0,772,39128,0,0,332,7426,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,155:8:0 0,12,101:4:0 0,15,128:5:0 +X 51 . C <*> 0 . DP=18;I16=18,0,0,0,681,26529,0,0,832,42728,0,0,353,7853,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,167:8:0 0,15,99:5:0 0,15,127:5:0 +X 52 . C <*> 0 . DP=18;I16=17,0,0,0,645,24983,0,0,803,41887,0,0,353,7965,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,164:8:0 0,12,99:4:0 0,15,128:5:0 +X 53 . C <*> 0 . DP=18;I16=18,0,0,0,687,26735,0,0,832,42728,0,0,359,8113,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,164:8:0 0,15,113:5:0 0,15,132:5:0 +X 54 . T <*> 0 . DP=18;I16=18,0,0,0,736,30194,0,0,832,42728,0,0,361,8219,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,163:8:0 0,15,128:5:0 0,15,136:5:0 +X 55 . G <*> 0 . DP=18;I16=18,0,0,0,674,26082,0,0,832,42728,0,0,362,8290,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,168:8:0 0,15,112:5:0 0,15,122:5:0 +X 56 . C <*> 0 . DP=18;I16=18,0,0,0,701,27645,0,0,832,42728,0,0,363,8375,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,162:8:0 0,15,121:5:0 0,15,131:5:0 +X 57 . T <*> 0 . DP=18;I16=17,0,0,0,694,29118,0,0,803,41887,0,0,356,8410,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,163:8:0 0,12,117:4:0 0,15,138:5:0 +X 58 . G <*> 0 . DP=17;I16=16,0,0,0,616,24356,0,0,774,41046,0,0,356,8454,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,159:7:0 0,12,95:4:0 0,15,131:5:0 +X 59 . A <*> 0 . DP=17;I16=17,0,0,0,656,26038,0,0,803,41887,0,0,366,8606,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,155:7:0 0,15,116:5:0 0,15,134:5:0 +X 60 . A <*> 0 . DP=17;I16=17,0,0,0,663,26463,0,0,803,41887,0,0,367,8687,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,151:7:0 0,15,127:5:0 0,15,138:5:0 +X 61 . T <*> 0 . DP=17;I16=16,0,0,0,605,23215,0,0,774,41046,0,0,355,8583,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,152:7:0 0,12,101:4:0 0,15,131:5:0 +X 62 . G <*> 0 . DP=18;I16=17,0,0,0,646,24868,0,0,834,44646,0,0,353,8557,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,158:7:0 0,12,103:4:0 0,18,141:6:0 +X 63 . T <*> 0 . DP=18;I16=17,0,0,0,590,21682,0,0,803,41887,0,0,341,8111,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,148:7:0 0,12,80:4:0 0,18,144:6:0 +X 64 . G <*> 0 . DP=19;I16=19,0,0,0,696,26416,0,0,923,49087,0,0,366,8758,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,169:8:0 0,15,103:5:0 0,18,142:6:0 +X 65 . C <*> 0 . DP=18;I16=18,0,0,0,686,26512,0,0,894,48246,0,0,367,8743,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,163:7:0 0,15,116:5:0 0,18,147:6:0 +X 66 . T <*> 0 . DP=18;I16=17,0,0,0,691,28315,0,0,834,44646,0,0,342,8068,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,164:7:0 0,12,110:4:0 0,18,153:6:0 +X 67 . C <*> 0 . DP=17;I16=17,0,0,0,645,25313,0,0,834,44646,0,0,341,7983,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,163:7:0 0,12,94:4:0 0,18,147:6:0 +X 68 . T <*> 0 . DP=17;I16=17,0,0,0,691,28307,0,0,834,44646,0,0,339,7863,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,165:7:0 0,12,108:4:0 0,18,151:6:0 +X 69 . G <*> 0 . DP=17;I16=17,0,0,0,657,25721,0,0,865,47405,0,0,338,7758,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,172:8:0 0,9,93:3:0 0,18,142:6:0 +X 70 . G <*> 0 . DP=17;I16=16,0,0,0,575,21391,0,0,836,46564,0,0,317,7227,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,162:8:0 0,6,64:2:0 0,18,141:6:0 +X 71 . G <*> 0 . DP=17;I16=15,0,0,0,571,21975,0,0,776,42964,0,0,307,7029,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,170:8:0 0,6,72:2:0 0,15,130:5:0 +X 72 . G <*> 0 . DP=17;I16=15,0,0,0,572,22002,0,0,776,42964,0,0,305,6907,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,171:8:0 0,6,65:2:0 0,15,131:5:0 +X 73 . T <*> 0 . DP=18;I16=16,0,0,0,623,25301,0,0,836,46564,0,0,314,6918,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,158:8:0 0,6,94:2:0 0,18,143:6:0 +X 74 . C <*> 0 . DP=18;I16=17,0,0,0,674,28110,0,0,865,47405,0,0,338,7468,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,176:8:0 0,9,106:3:0 0,18,141:6:0 +X 75 . T <*> 0 . DP=18;I16=16,0,0,0,685,30675,0,0,836,46564,0,0,312,6782,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,175:8:0 0,6,90:2:0 0,18,150:6:0 +X 76 . C <*> 0 . DP=18;I16=17,0,0,0,683,29481,0,0,865,47405,0,0,336,7360,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,174:8:0 0,9,98:3:0 0,18,148:6:0 +X 77 . T <*> 0 . DP=18;I16=16,0,0,0,710,33072,0,0,836,46564,0,0,310,6702,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,179:8:0 0,6,92:2:0 0,18,154:6:0 +X 78 . G <*> 0 . DP=18;I16=16,0,0,0,692,31158,0,0,836,46564,0,0,309,6683,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,180:8:0 0,6,94:2:0 0,18,149:6:0 +X 79 . G <*> 0 . DP=18;I16=15,0,0,0,605,26629,0,0,776,42964,0,0,283,6053,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,168:8:0 0,3,60:1:0 0,18,149:6:0 +X 80 . G <*> 0 . DP=18;I16=17,0,0,0,688,30128,0,0,865,47405,0,0,332,7312,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,173:8:0 0,9,106:3:0 0,18,151:6:0 +X 81 . G <*> 0 . DP=18;I16=16,0,0,0,631,27429,0,0,836,46564,0,0,326,7310,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,165:7:0 0,9,97:3:0 0,18,145:6:0 +X 82 . T <*> 0 . DP=18;I16=15,0,0,0,559,22735,0,0,776,42964,0,0,280,6122,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,154:8:0 0,3,60:1:0 0,18,131:6:0 +X 83 . C <*> 0 . DP=18;I16=16,0,0,0,622,27146,0,0,836,46564,0,0,304,6798,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,170:8:0 0,6,75:2:0 0,18,145:6:0 +X 84 . T <*> 0 . DP=18;I16=17,0,0,0,705,32445,0,0,865,47405,0,0,328,7488,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,181:8:0 0,9,85:3:0 0,18,154:6:0 +X 85 . C <*> 0 . DP=18;I16=17,0,0,0,708,31222,0,0,865,47405,0,0,327,7567,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,181:8:0 0,9,108:3:0 0,18,153:6:0 +X 86 . A <*> 0 . DP=18;I16=17,0,0,0,692,29540,0,0,865,47405,0,0,326,7660,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,169:8:0 0,9,111:3:0 0,18,149:6:0 +X 87 . C <*> 0 . DP=18;I16=17,0,0,0,683,29493,0,0,896,50164,0,0,326,7766,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,174:8:0 0,9,103:3:0 0,18,148:6:0 +X 88 . C <*> 0 . DP=18;I16=17,0,0,0,703,31005,0,0,896,50164,0,0,326,7834,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,174:8:0 0,9,113:3:0 0,18,153:6:0 +X 89 . C <*> 0 . DP=18;I16=17,0,0,0,697,30875,0,0,896,50164,0,0,326,7914,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,176:8:0 0,9,103:3:0 0,18,154:6:0 +X 90 . A <*> 0 . DP=17;I16=16,0,0,0,668,29732,0,0,867,49323,0,0,326,7954,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,173:8:0 0,9,114:3:0 0,15,138:5:0 +X 91 . C <*> 0 . DP=16;I16=15,0,0,0,613,26409,0,0,838,48482,0,0,327,8001,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,170:7:0 0,9,113:3:0 0,15,133:5:0 +X 92 . G <*> 0 . DP=16;I16=15,0,0,0,499,18731,0,0,838,48482,0,0,328,8054,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,143:7:0 0,9,100:3:0 0,15,96:5:0 +X 93 . A <*> 0 . DP=16;I16=15,0,0,0,635,28655,0,0,869,51241,0,0,329,8063,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,167:7:0 0,9,108:3:0 0,15,145:5:0 +X 94 . C <*> 0 . DP=16;I16=15,0,0,0,607,25893,0,0,869,51241,0,0,331,8079,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,166:7:0 0,9,105:3:0 0,15,135:5:0 +X 95 . C <*> 0 . DP=17;I16=15,0,0,0,615,26761,0,0,900,54000,0,0,306,7378,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,178:8:0 0,6,91:2:0 0,15,135:5:0 +X 96 . A <*> 0 . DP=17;I16=16,0,0,0,625,26705,0,0,929,54841,0,0,332,7936,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,172:8:0 0,9,99:3:0 0,15,134:5:0 +X 97 . A <*> 0 . DP=18;I16=17,0,0,0,675,29017,0,0,958,55682,0,0,333,7879,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,179:9:0 0,9,104:3:0 0,15,145:5:0 +X 98 . C <*> 0 . DP=18;I16=17,0,0,0,655,27231,0,0,958,55682,0,0,333,7735,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,179:9:0 0,9,105:3:0 0,15,131:5:0 +X 99 . T <*> 0 . DP=18;I16=17,0,0,0,720,32840,0,0,958,55682,0,0,333,7607,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,186:9:0 0,9,115:3:0 0,15,153:5:0 +X 100 . C <*> 0 . DP=18;I16=17,0,0,0,688,29762,0,0,958,55682,0,0,332,7446,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,189:9:0 0,9,108:3:0 0,15,134:5:0 +X 101 . C <*> 0 . DP=18;I16=17,0,0,0,650,27530,0,0,958,55682,0,0,331,7303,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,182:9:0 0,9,99:3:0 0,15,132:5:0 +X 102 . C <*> 0 . DP=18;I16=17,0,0,0,695,30453,0,0,958,55682,0,0,330,7178,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,188:9:0 0,9,111:3:0 0,15,139:5:0 +X 103 . T <*> 0 . DP=18;I16=16,0,0,0,692,31998,0,0,929,54841,0,0,323,7035,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,189:8:0 0,9,108:3:0 0,15,147:5:0 +X 104 . G <*> 0 . DP=18;I16=15,0,0,0,611,26723,0,0,900,54000,0,0,295,6259,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,178:8:0 0,6,89:2:0 0,15,133:5:0 +X 105 . G <*> 0 . DP=19;I16=17,0,0,0,604,23936,0,0,989,58441,0,0,317,6751,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,170:9:0 0,9,97:3:0 0,15,125:5:0 +X 106 . G <*> 0 . DP=19;I16=17,0,0,0,644,26574,0,0,989,58441,0,0,299,6093,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,30,190:10:0 0,6,85:2:0 0,15,124:5:0 +X 107 . C <*> 0 . DP=19;I16=17,0,0,0,694,30064,0,0,989,58441,0,0,313,6543,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,192:9:0 0,9,108:3:0 0,15,136:5:0 +X 108 . C <*> 0 . DP=19;I16=17,0,0,0,692,30148,0,0,989,58441,0,0,310,6420,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,190:9:0 0,9,108:3:0 0,15,135:5:0 +X 109 . T <*> 0 . DP=19;I16=17,0,0,0,741,34273,0,0,989,58441,0,0,307,6319,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,195:9:0 0,9,110:3:0 0,15,150:5:0 +X 110 . G <*> 0 . DP=19;I16=17,0,0,0,704,31276,0,0,989,58441,0,0,304,6240,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,194:9:0 0,9,104:3:0 0,15,136:5:0 +X 111 . G <*> 0 . DP=19;I16=16,0,0,0,584,24362,0,0,929,54841,0,0,272,5416,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,30,167:10:0 0,6,88:2:0 0,12,118:4:0 +X 112 . C <*> 0 . DP=19;I16=17,0,0,0,680,29854,0,0,989,58441,0,0,296,6052,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,191:9:0 0,9,95:3:0 0,15,135:5:0 +X 113 . A <*> 0 . DP=19;I16=16,0,0,0,645,28035,0,0,960,57600,0,0,266,5318,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,176:9:0 0,6,87:2:0 0,15,139:5:0 +X 114 . C <*> 0 . DP=19;I16=17,0,0,0,674,28788,0,0,989,58441,0,0,286,5856,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,182:9:0 0,9,103:3:0 0,15,133:5:0 +X 115 . C <*> 0 . DP=21;I16=18,0,0,0,708,30546,0,0,1049,62041,0,0,274,5490,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,30,189:10:0 0,6,89:2:0 0,18,147:6:0 +X 116 . A <*> 0 . DP=21;I16=17,1,0,0,727,31755,0,0,1049,62041,0,0,253,5079,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,183:9:0 0,6,90:2:0 0,21,175:7:0 +X 117 . G <*> 0 . DP=21;I16=17,1,0,0,723,31221,0,0,1049,62041,0,0,249,5019,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,186:9:0 0,6,86:2:0 0,21,177:7:0 +X 118 . G <*> 0 . DP=20;I16=16,1,0,0,636,26574,0,0,958,55682,0,0,266,5426,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,175:9:0 0,3,60:1:0 0,21,162:7:0 +X 119 . G <*> 0 . DP=19;I16=16,1,0,0,629,26439,0,0,958,55682,0,0,267,5553,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,175:8:0 0,6,73:2:0 0,21,160:7:0 +X 120 . A <*> 0 . DP=19;I16=16,1,0,0,672,29188,0,0,958,55682,0,0,264,5518,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,175:8:0 0,6,83:2:0 0,21,171:7:0 +X 121 . G <*> 0 . DP=19;I16=16,1,0,0,662,28460,0,0,958,55682,0,0,260,5454,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,181:8:0 0,6,80:2:0 0,21,168:7:0 +X 122 . C <*> 0 . DP=20;I16=17,1,0,0,716,31224,0,0,1018,59282,0,0,256,5410,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,181:8:0 0,9,99:3:0 0,21,178:7:0 +X 123 . T <*> 0 . DP=18;I16=15,1,0,0,661,29997,0,0,898,52082,0,0,255,5385,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,167:7:0 0,9,112:3:0 0,18,166:6:0 +X 124 . T <*> 0 . DP=19;I16=17,1,0,0,626,24802,0,0,987,56523,0,0,279,6003,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,154:9:0 0,9,104:3:0 0,18,154:6:0 +X 125 . A <*> 0 . DP=18;I16=15,1,0,0,611,25689,0,0,898,52082,0,0,254,5340,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,154:7:0 0,9,104:3:0 0,18,162:6:0 +X 126 . A <*> 0 . DP=18;I16=16,1,0,0,648,27366,0,0,927,52923,0,0,279,5947,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,162:8:0 0,9,107:3:0 0,18,174:6:0 +X 127 . C <*> 0 . DP=18;I16=16,1,0,0,646,26972,0,0,927,52923,0,0,279,5949,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,163:8:0 0,9,109:3:0 0,18,160:6:0 +X 128 . A <*> 0 . DP=18;I16=16,1,0,0,673,28797,0,0,927,52923,0,0,279,5971,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,169:8:0 0,9,111:3:0 0,18,162:6:0 +X 129 . A <*> 0 . DP=17;I16=15,1,0,0,645,27891,0,0,867,49323,0,0,280,6012,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,168:8:0 0,9,113:3:0 0,15,159:5:0 +X 130 . A <*> 0 . DP=17;I16=15,1,0,0,641,27295,0,0,867,49323,0,0,281,6071,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,169:8:0 0,9,113:3:0 0,15,152:5:0 +X 131 . C <*> 0 . DP=16;I16=14,1,0,0,606,25732,0,0,838,48482,0,0,256,5472,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,167:7:0 0,9,110:3:0 0,15,147:5:0 +X 132 . A <*> 0 . DP=16;I16=14,1,0,0,627,27579,0,0,838,48482,0,0,256,5514,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,169:7:0 0,9,110:3:0 0,15,151:5:0 +X 133 . T <*> 0 . DP=15;I16=13,2,0,0,584,22816,0,0,838,48482,0,0,282,6196,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,163:7:0 0,9,105:3:0 0,15,150:5:0 +X 134 . C <*> 0 . DP=15;I16=13,2,0,0,607,24653,0,0,838,48482,0,0,283,6267,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,177:7:0 0,9,105:3:0 0,15,152:5:0 +X 135 . T <*> 0 . DP=15;I16=13,2,0,0,600,24178,0,0,838,48482,0,0,284,6352,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,173:7:0 0,9,106:3:0 0,15,156:5:0 +X 136 . G <*> 0 . DP=15;I16=13,2,0,0,574,22258,0,0,838,48482,0,0,286,6450,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,172:7:0 0,9,105:3:0 0,15,134:5:0 +X 137 . T <*> 0 . DP=15;I16=13,2,0,0,563,21377,0,0,838,48482,0,0,289,6561,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,160:7:0 0,9,104:3:0 0,15,139:5:0 +X 138 . C <*> 0 . DP=15;I16=13,2,0,0,584,23088,0,0,838,48482,0,0,291,6637,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,172:7:0 0,9,108:3:0 0,15,142:5:0 +X 139 . C <*> 0 . DP=15;I16=13,2,0,0,554,20790,0,0,838,48482,0,0,292,6680,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,161:7:0 0,9,106:3:0 0,15,143:5:0 +X 140 . A <*> 0 . DP=15;I16=13,2,0,0,583,22789,0,0,838,48482,0,0,292,6690,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,163:7:0 0,9,107:3:0 0,15,153:5:0 +X 141 . G <*> 0 . DP=14;I16=12,2,0,0,534,20750,0,0,778,44882,0,0,292,6664,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,158:6:0 0,9,108:3:0 0,15,142:5:0 +X 142 . C <*> 0 . DP=14;I16=12,2,0,0,503,18593,0,0,778,44882,0,0,292,6650,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,157:6:0 0,9,97:3:0 0,15,129:5:0 +X 143 . G <*> 0 . DP=14;I16=11,2,0,0,415,13657,0,0,718,41282,0,0,285,6599,0,0;QS=3,0;MQSB=0.590909;MQ0F=0 PL:DP:DV 0,18,128:6:0 0,9,95:3:0 0,12,97:4:0 +X 144 . A <*> 0 . DP=14;I16=12,2,0,0,519,19725,0,0,778,44882,0,0,291,6609,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,152:6:0 0,9,105:3:0 0,15,129:5:0 +X 145 . A <*> 0 . DP=14;I16=12,2,0,0,527,20289,0,0,778,44882,0,0,290,6584,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,153:6:0 0,9,106:3:0 0,15,138:5:0 +X 146 . T <*> 0 . DP=14;I16=12,2,0,0,514,19484,0,0,778,44882,0,0,289,6573,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,152:6:0 0,9,103:3:0 0,15,128:5:0 +X 147 . A <*> 0 . DP=14;I16=12,2,0,0,515,19213,0,0,778,44882,0,0,288,6576,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,150:6:0 0,9,99:3:0 0,15,140:5:0 +X 148 . C <*> 0 . DP=14;I16=12,2,0,0,541,21019,0,0,778,44882,0,0,286,6542,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,157:6:0 0,9,106:3:0 0,15,146:5:0 +X 149 . C <*> 0 . DP=14;I16=12,2,0,0,512,19326,0,0,778,44882,0,0,283,6471,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,148:6:0 0,9,109:3:0 0,15,140:5:0 +X 150 . T <*> 0 . DP=13;I16=11,2,0,0,511,20251,0,0,749,44041,0,0,280,6362,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,153:6:0 0,6,84:2:0 0,15,152:5:0 +X 151 . G <*> 0 . DP=13;I16=11,2,0,0,506,19826,0,0,749,44041,0,0,277,6263,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,157:6:0 0,6,84:2:0 0,15,144:5:0 +X 152 . C <*> 0 . DP=14;I16=12,2,0,0,543,21283,0,0,809,47641,0,0,274,6174,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,168:7:0 0,6,84:2:0 0,15,146:5:0 +X 153 . A <*> 0 . DP=14;I16=12,2,0,0,536,20594,0,0,809,47641,0,0,272,6096,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,156:7:0 0,6,81:2:0 0,15,153:5:0 +X 154 . T <*> 0 . DP=14;I16=12,2,0,0,523,20051,0,0,809,47641,0,0,270,6030,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,159:7:0 0,6,83:2:0 0,15,139:5:0 +X 155 . C <*> 0 . DP=14;I16=12,2,0,0,542,21254,0,0,809,47641,0,0,268,5976,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,172:7:0 0,6,85:2:0 0,15,139:5:0 +X 156 . C <*> 0 . DP=14;I16=12,2,0,0,536,20884,0,0,809,47641,0,0,266,5934,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,163:7:0 0,6,84:2:0 0,15,150:5:0 +X 157 . C <*> 0 . DP=14;I16=12,2,0,0,555,22081,0,0,809,47641,0,0,264,5904,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,169:7:0 0,6,85:2:0 0,15,149:5:0 +X 158 . T <*> 0 . DP=14;I16=12,2,0,0,568,23154,0,0,809,47641,0,0,262,5886,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,170:7:0 0,6,84:2:0 0,15,159:5:0 +X 159 . A <*> 0 . DP=15;I16=12,2,0,0,519,19467,0,0,809,47641,0,0,260,5880,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,157:7:0 0,6,83:2:0 0,15,135:5:0 +X 160 . G <*> 0 . DP=15;I16=13,2,0,0,547,20633,0,0,869,51241,0,0,259,5887,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,165:7:0 0,6,85:2:0 0,18,139:6:0 +X 161 . A <*> 0 . DP=15;I16=13,2,0,0,568,21610,0,0,869,51241,0,0,258,5908,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,157:7:0 0,6,83:2:0 0,18,162:6:0 +X 162 . A <*> 0 . DP=15;I16=13,2,0,0,557,21139,0,0,869,51241,0,0,255,5843,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,147:7:0 0,6,87:2:0 0,18,167:6:0 +X 163 . G <*> 0 . DP=14;I16=12,2,0,0,503,18645,0,0,809,47641,0,0,253,5791,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,153:7:0 0,6,79:2:0 0,15,138:5:0 +X 164 . T <*> 0 . DP=14;I16=12,2,0,0,460,15968,0,0,809,47641,0,0,252,5750,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,131:6:0 0,6,79:2:0 0,18,136:6:0 +X 165 . G <*> 0 . DP=14;I16=10,2,0,0,456,17460,0,0,689,40441,0,0,226,5094,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,149:6:0 0,6,80:2:0 0,12,122:4:0 +X 166 . A <*> 0 . DP=14;I16=11,2,0,0,496,19138,0,0,749,44041,0,0,227,5077,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,145:6:0 0,6,82:2:0 0,15,148:5:0 +X 167 . A <*> 0 . DP=14;I16=11,2,0,0,477,17851,0,0,749,44041,0,0,227,5071,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,132:6:0 0,6,86:2:0 0,15,147:5:0 +X 168 . G <*> 0 . DP=14;I16=12,2,0,0,481,18015,0,0,809,47641,0,0,252,5702,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,145:6:0 0,6,82:2:0 0,18,140:6:0 +X 169 . C <*> 0 . DP=13;I16=10,2,0,0,402,14224,0,0,689,40441,0,0,227,5045,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,15,106:5:0 0,6,76:2:0 0,15,145:5:0 +X 170 . C <*> 0 . DP=13;I16=11,2,0,0,447,16383,0,0,749,44041,0,0,251,5601,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,15,128:5:0 0,6,80:2:0 0,18,143:6:0 +X 171 . A <*> 0 . DP=13;I16=11,2,0,0,500,19366,0,0,749,44041,0,0,250,5546,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,15,134:5:0 0,6,81:2:0 0,18,166:6:0 +X 172 . C <*> 0 . DP=13;I16=10,2,0,0,439,16395,0,0,689,40441,0,0,241,5441,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,15,138:5:0 0,6,75:2:0 0,15,129:5:0 +X 173 . C <*> 0 . DP=13;I16=11,2,0,0,435,15225,0,0,749,44041,0,0,248,5478,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,15,121:5:0 0,6,76:2:0 0,18,146:6:0 +X 174 . G <*> 0 . DP=13;I16=11,1,0,0,351,10685,0,0,689,40441,0,0,238,5364,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,111:5:0 0,3,27:1:0 0,18,117:6:0 +X 175 . C <*> 0 . DP=14;I16=13,1,0,0,511,19161,0,0,809,47641,0,0,249,5463,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,143:6:0 0,3,41:1:0 0,21,175:7:0 +X 176 . C <*> 0 . DP=14;I16=13,1,0,0,489,17733,0,0,809,47641,0,0,251,5477,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,146:6:0 0,3,44:1:0 0,21,152:7:0 +X 177 . C <*> 0 . DP=14;I16=13,1,0,0,488,17328,0,0,809,47641,0,0,253,5507,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,138:6:0 0,3,44:1:0 0,21,158:7:0 +X 178 . A <*> 0 . DP=14;I16=13,1,0,0,519,19485,0,0,809,47641,0,0,254,5502,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,147:6:0 0,3,42:1:0 0,21,172:7:0 +X 179 . A <*> 0 . DP=14;I16=13,1,0,0,478,17278,0,0,809,47641,0,0,255,5511,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,134:6:0 0,3,44:1:0 0,21,170:7:0 +X 180 . A <*> 0 . DP=14;I16=12,1,0,0,425,14653,0,0,749,44041,0,0,250,5498,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,126:6:0 0,3,43:1:0 0,18,148:6:0 +X 181 . G <*> 0 . DP=14;I16=11,1,0,0,450,17152,0,0,689,40441,0,0,233,5233,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,156:6:0 0,3,41:1:0 0,15,138:5:0 +X 182 . A <*> 0 . DP=15;I16=14,1,0,0,515,18235,0,0,869,51241,0,0,258,5622,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,150:7:0 0,3,43:1:0 0,21,159:7:0 +X 183 . C <*> 0 . DP=15;I16=13,1,0,0,483,17419,0,0,809,47641,0,0,235,5063,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,159:7:0 0,3,40:1:0 0,18,139:6:0 +X 184 . A <*> 0 . DP=15;I16=14,1,0,0,535,19667,0,0,869,51241,0,0,262,5770,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,158:7:0 0,3,41:1:0 0,21,163:7:0 +X 185 . C <*> 0 . DP=15;I16=13,1,0,0,487,17295,0,0,809,47641,0,0,238,5192,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,150:7:0 0,3,38:1:0 0,18,160:6:0 +X 186 . G <*> 0 . DP=15;I16=12,1,0,0,381,11429,0,0,749,44041,0,0,239,5253,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,117:6:0 0,3,32:1:0 0,18,124:6:0 +X 187 . C <*> 0 . DP=14;I16=13,1,0,0,511,18979,0,0,809,47641,0,0,266,5952,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,147:6:0 0,3,38:1:0 0,21,172:7:0 +X 188 . C <*> 0 . DP=14;I16=13,1,0,0,496,18042,0,0,809,47641,0,0,267,5989,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,147:6:0 0,3,37:1:0 0,21,162:7:0 +X 189 . C <*> 0 . DP=15;I16=13,2,0,0,552,20504,0,0,838,48482,0,0,268,6040,0,0;QS=3,0;MQSB=0;MQ0F=0 PL:DP:DV 0,18,152:6:0 0,6,67:2:0 0,21,167:7:0 +X 190 . A <*> 0 . DP=15;I16=12,2,0,0,500,18230,0,0,778,44882,0,0,243,5381,0,0;QS=3,0;MQSB=0;MQ0F=0 PL:DP:DV 0,18,138:6:0 0,6,68:2:0 0,18,159:6:0 +X 191 . T <*> 0 . DP=15;I16=13,2,0,0,534,19276,0,0,838,48482,0,0,267,5939,0,0;QS=3,0;MQSB=0;MQ0F=0 PL:DP:DV 0,18,143:6:0 0,6,67:2:0 0,21,169:7:0 +X 192 . G <*> 0 . DP=15;I16=13,2,0,0,499,17439,0,0,838,48482,0,0,266,5890,0,0;QS=3,0;MQSB=0;MQ0F=0 PL:DP:DV 0,18,143:6:0 0,6,67:2:0 0,21,151:7:0 +X 193 . T <*> 0 . DP=15;I16=13,2,0,0,505,17811,0,0,838,48482,0,0,265,5859,0,0;QS=3,0;MQSB=0;MQ0F=0 PL:DP:DV 0,18,140:6:0 0,6,63:2:0 0,21,157:7:0 +X 194 . C <*> 0 . DP=14;I16=12,2,0,0,467,16569,0,0,778,44882,0,0,265,5845,0,0;QS=3,0;MQSB=0;MQ0F=0 PL:DP:DV 0,18,142:6:0 0,6,67:2:0 0,18,145:6:0 +X 195 . C <*> 0 . DP=14;I16=11,3,0,0,503,18647,0,0,747,42123,0,0,266,5846,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,18,159:6:0 0,6,71:2:0 0,18,160:6:0 +X 196 . A <*> 0 . DP=14;I16=11,3,0,0,482,17400,0,0,747,42123,0,0,268,5862,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,18,166:6:0 0,6,69:2:0 0,18,138:6:0 +X 197 . G <*> 0 . DP=14;I16=11,3,0,0,481,17391,0,0,747,42123,0,0,270,5894,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,18,164:6:0 0,6,68:2:0 0,18,134:6:0 +X 198 . C <*> 0 . DP=14;I16=11,3,0,0,539,20957,0,0,747,42123,0,0,271,5893,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,18,172:6:0 0,6,70:2:0 0,18,164:6:0 +X 199 . T <*> 0 . DP=14;I16=11,3,0,0,505,19197,0,0,747,42123,0,0,271,5861,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,18,162:6:0 0,6,73:2:0 0,18,154:6:0 +X 200 . T <*> 0 . DP=15;I16=11,4,0,0,544,19918,0,0,776,42964,0,0,270,5798,0,0;QS=3,0;MQSB=0.0161635;MQ0F=0 PL:DP:DV 0,18,161:6:0 0,9,89:3:0 0,18,154:6:0 +X 201 . A <*> 0 . DP=16;I16=12,4,0,0,568,20416,0,0,836,46564,0,0,269,5703,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,171:7:0 0,9,89:3:0 0,18,157:6:0 +X 202 . A <*> 0 . DP=16;I16=12,4,0,0,566,20590,0,0,836,46564,0,0,269,5627,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,178:7:0 0,9,84:3:0 0,18,163:6:0 +X 203 . C <*> 0 . DP=16;I16=12,4,0,0,557,20119,0,0,836,46564,0,0,269,5571,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,166:7:0 0,9,90:3:0 0,18,153:6:0 +X 204 . C <*> 0 . DP=16;I16=12,4,0,0,591,22379,0,0,836,46564,0,0,269,5535,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,173:7:0 0,9,91:3:0 0,18,163:6:0 +X 205 . T <*> 0 . DP=16;I16=12,4,0,0,635,25281,0,0,836,46564,0,0,269,5519,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,188:7:0 0,9,95:3:0 0,18,173:6:0 +X 206 . G <*> 0 . DP=16;I16=12,4,0,0,577,21337,0,0,836,46564,0,0,269,5523,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,180:7:0 0,9,89:3:0 0,18,143:6:0 +X 207 . C <*> 0 . DP=16;I16=12,4,0,0,574,21076,0,0,836,46564,0,0,269,5547,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,179:7:0 0,9,93:3:0 0,18,151:6:0 +X 208 . A <*> 0 . DP=16;I16=12,4,0,0,576,21486,0,0,836,46564,0,0,268,5540,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,184:7:0 0,9,93:3:0 0,18,154:6:0 +X 209 . T <*> 0 . DP=16;I16=12,4,0,0,567,20475,0,0,836,46564,0,0,267,5551,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,173:7:0 0,9,91:3:0 0,18,146:6:0 +X 210 . C <*> 0 . DP=16;I16=12,4,0,0,577,21109,0,0,836,46564,0,0,266,5580,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,185:7:0 0,9,92:3:0 0,18,151:6:0 +X 211 . C <*> 0 . DP=16;I16=12,4,0,0,563,20227,0,0,836,46564,0,0,265,5627,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,172:7:0 0,9,92:3:0 0,18,153:6:0 +X 212 . C <*> 0 . DP=16;I16=12,4,0,0,589,22179,0,0,836,46564,0,0,263,5643,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,181:7:0 0,9,92:3:0 0,18,152:6:0 +X 213 . T <*> 0 . DP=16;I16=12,4,0,0,598,22838,0,0,836,46564,0,0,262,5678,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,181:7:0 0,9,95:3:0 0,18,165:6:0 +X 214 . A <*> 0 . DP=16;I16=11,4,0,0,529,19401,0,0,776,42964,0,0,240,5248,0,0;QS=3,0;MQSB=0.0161635;MQ0F=0 PL:DP:DV 0,21,176:7:0 0,9,92:3:0 0,15,118:5:0 +X 215 . G <*> 0 . DP=15;I16=12,3,0,0,521,19073,0,0,807,45723,0,0,262,5754,0,0;QS=3,0;MQSB=0.0342181;MQ0F=0 PL:DP:DV 0,21,185:7:0 0,9,90:3:0 0,15,105:5:0 +X 216 . A <*> 0 . DP=14;I16=10,3,0,0,464,16900,0,0,687,38523,0,0,238,5166,0,0;QS=3,0;MQSB=0.040184;MQ0F=0 PL:DP:DV 0,21,173:7:0 0,9,92:3:0 0,9,81:3:0 +X 217 . A <*> 0 . DP=14;I16=11,3,0,0,515,19433,0,0,747,42123,0,0,264,5842,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,21,181:7:0 0,9,90:3:0 0,12,97:4:0 +X 218 . G <*> 0 . DP=14;I16=11,3,0,0,507,18957,0,0,747,42123,0,0,265,5907,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,21,178:7:0 0,9,90:3:0 0,12,110:4:0 +X 219 . T <*> 0 . DP=14;I16=11,3,0,0,470,16286,0,0,747,42123,0,0,266,5986,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,21,173:7:0 0,9,88:3:0 0,12,89:4:0 +X 220 . G <*> 0 . DP=14;I16=10,3,0,0,485,18307,0,0,687,38523,0,0,242,5454,0,0;QS=3,0;MQSB=0.040184;MQ0F=0 PL:DP:DV 0,21,188:7:0 0,9,88:3:0 0,9,80:3:0 +X 221 . A <*> 0 . DP=14;I16=11,3,0,0,487,17615,0,0,747,42123,0,0,267,6135,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,21,176:7:0 0,9,88:3:0 0,12,101:4:0 +X 222 . A <*> 0 . DP=14;I16=10,3,0,0,465,17367,0,0,687,38523,0,0,242,5578,0,0;QS=3,0;MQSB=0.040184;MQ0F=0 PL:DP:DV 0,21,186:7:0 0,9,85:3:0 0,9,69:3:0 +X 223 . G <*> 0 . DP=13;I16=9,3,0,0,405,14327,0,0,627,34923,0,0,243,5657,0,0;QS=3,0;MQSB=0.0443614;MQ0F=0 PL:DP:DV 0,18,168:6:0 0,6,53:2:0 0,12,81:4:0 +X 224 . G <*> 0 . DP=12;I16=9,3,0,0,379,12759,0,0,627,34923,0,0,270,6370,0,0;QS=3,0;MQSB=0.0443614;MQ0F=0 PL:DP:DV 0,18,168:6:0 0,6,50:2:0 0,12,70:4:0 +X 225 . C <*> 0 . DP=12;I16=8,3,0,0,382,13896,0,0,567,31323,0,0,261,6345,0,0;QS=3,0;MQSB=0.0497871;MQ0F=0 PL:DP:DV 0,18,165:6:0 0,6,48:2:0 0,9,83:3:0 +X 226 . A <*> 0 . DP=13;I16=8,3,0,0,381,13669,0,0,567,31323,0,0,248,5894,0,0;QS=3,0;MQSB=0.0497871;MQ0F=0 PL:DP:DV 0,18,166:6:0 0,6,53:2:0 0,9,84:3:0 +X 227 . C <*> 0 . DP=13;I16=8,4,0,0,406,14306,0,0,596,32164,0,0,267,6253,0,0;QS=3,0;MQSB=0.0249144;MQ0F=0 PL:DP:DV 0,21,190:7:0 0,6,53:2:0 0,9,73:3:0 +X 228 . C <*> 0 . DP=13;I16=9,4,0,0,417,14381,0,0,656,35764,0,0,292,6884,0,0;QS=3,0;MQSB=0.0211283;MQ0F=0 PL:DP:DV 0,21,187:7:0 0,6,45:2:0 0,12,96:4:0 +X 229 . G <*> 0 . DP=13;I16=9,3,0,0,358,11424,0,0,627,34923,0,0,270,6414,0,0;QS=3,0;MQSB=0.0443614;MQ0F=0 PL:DP:DV 0,18,136:6:0 0,6,53:2:0 0,12,70:4:0 +X 230 . C <*> 0 . DP=13;I16=9,4,0,0,461,16861,0,0,656,35764,0,0,292,6920,0,0;QS=3,0;MQSB=0.0211283;MQ0F=0 PL:DP:DV 0,21,186:7:0 0,6,53:2:0 0,12,100:4:0 +X 231 . C <*> 0 . DP=13;I16=7,4,0,0,414,15832,0,0,536,28564,0,0,247,5925,0,0;QS=3,0;MQSB=0.0401934;MQ0F=0 PL:DP:DV 0,18,184:6:0 0,6,53:2:0 0,9,82:3:0 +X 232 . C <*> 0 . DP=14;I16=9,4,0,0,471,17371,0,0,656,35764,0,0,267,6363,0,0;QS=3,0;MQSB=0.0211283;MQ0F=0 PL:DP:DV 0,21,198:7:0 0,6,53:2:0 0,12,101:4:0 +X 233 . A <*> 0 . DP=14;I16=10,4,0,0,496,18142,0,0,716,39364,0,0,292,6984,0,0;QS=3,0;MQSB=0.0183156;MQ0F=0 PL:DP:DV 0,21,192:7:0 0,6,53:2:0 0,15,119:5:0 +X 234 . A <*> 0 . DP=14;I16=10,4,0,0,502,18390,0,0,716,39364,0,0,292,6988,0,0;QS=3,0;MQSB=0.0183156;MQ0F=0 PL:DP:DV 0,21,185:7:0 0,6,53:2:0 0,15,123:5:0 +X 235 . A <*> 0 . DP=14;I16=9,4,0,0,476,17652,0,0,656,35764,0,0,267,6375,0,0;QS=3,0;MQSB=0.0211283;MQ0F=0 PL:DP:DV 0,21,186:7:0 0,6,53:2:0 0,12,111:4:0 +X 236 . G <*> 0 . DP=15;I16=11,4,0,0,501,17481,0,0,776,42964,0,0,290,6924,0,0;QS=3,0;MQSB=0.0161635;MQ0F=0 PL:DP:DV 0,24,206:8:0 0,6,53:2:0 0,15,103:5:0 +X 237 . A <*> 0 . DP=14;I16=9,4,0,0,465,16877,0,0,656,35764,0,0,266,6282,0,0;QS=3,0;MQSB=0.0211283;MQ0F=0 PL:DP:DV 0,24,206:8:0 0,6,53:2:0 0,9,92:3:0 +X 238 . C <*> 0 . DP=14;I16=10,4,0,0,482,17238,0,0,716,39364,0,0,292,6900,0,0;QS=3,0;MQSB=0.0183156;MQ0F=0 PL:DP:DV 0,24,211:8:0 0,6,53:2:0 0,12,82:4:0 +X 239 . A <*> 0 . DP=15;I16=10,5,0,0,525,19155,0,0,776,42964,0,0,292,6852,0,0;QS=3,0;MQSB=0.0497871;MQ0F=0 PL:DP:DV 0,27,223:9:0 0,6,50:2:0 0,12,108:4:0 +X 240 . C <*> 0 . DP=15;I16=10,5,0,0,512,17930,0,0,776,42964,0,0,292,6764,0,0;QS=3,0;MQSB=0.0497871;MQ0F=0 PL:DP:DV 0,27,220:9:0 0,6,53:2:0 0,12,106:4:0 +X 241 . G <*> 0 . DP=15;I16=9,5,0,0,444,14636,0,0,716,39364,0,0,269,6159,0,0;QS=3,0;MQSB=0.0561348;MQ0F=0 PL:DP:DV 0,27,203:9:0 0,6,53:2:0 0,9,59:3:0 +X 242 . C <*> 0 . DP=15;I16=10,5,0,0,555,21177,0,0,776,42964,0,0,292,6624,0,0;QS=3,0;MQSB=0.0497871;MQ0F=0 PL:DP:DV 0,27,242:9:0 0,6,53:2:0 0,12,94:4:0 +X 243 . C <*> 0 . DP=16;I16=9,5,0,0,523,19737,0,0,716,39364,0,0,284,6508,0,0;QS=3,0;MQSB=0.0561348;MQ0F=0 PL:DP:DV 0,24,220:8:0 0,6,53:2:0 0,12,104:4:0 +X 244 . C <*> 0 . DP=16;I16=10,6,0,0,620,24272,0,0,805,43805,0,0,298,6568,0,0;QS=3,0;MQSB=0.0253122;MQ0F=0 PL:DP:DV 0,27,245:9:0 0,9,72:3:0 0,12,106:4:0 +X 245 . A <*> 0 . DP=17;I16=10,7,0,0,649,24843,0,0,865,47405,0,0,299,6553,0,0;QS=3,0;MQSB=0.0509867;MQ0F=0 PL:DP:DV 0,27,236:9:0 0,12,93:4:0 0,12,115:4:0 +X 246 . T <*> 0 . DP=18;I16=10,8,0,0,649,23833,0,0,894,48246,0,0,301,6553,0,0;QS=3,0;MQSB=0.0286491;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,12,94:4:0 0,12,98:4:0 +X 247 . G <*> 0 . DP=18;I16=10,8,0,0,642,23610,0,0,894,48246,0,0,304,6570,0,0;QS=3,0;MQSB=0.0286491;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,12,83:4:0 0,12,103:4:0 +X 248 . T <*> 0 . DP=18;I16=10,8,0,0,636,22944,0,0,894,48246,0,0,307,6605,0,0;QS=3,0;MQSB=0.0286491;MQ0F=0 PL:DP:DV 0,30,234:10:0 0,12,86:4:0 0,12,114:4:0 +X 249 . C <*> 0 . DP=18;I16=10,8,0,0,656,24846,0,0,894,48246,0,0,310,6658,0,0;QS=3,0;MQSB=0.0286491;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,12,79:4:0 0,12,112:4:0 +X 250 . C <*> 0 . DP=19;I16=10,9,0,0,694,26160,0,0,923,49087,0,0,311,6631,0,0;QS=3,0;MQSB=0.0168512;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,12,89:4:0 0,15,142:5:0 +X 251 . A <*> 0 . DP=19;I16=9,9,0,0,688,26506,0,0,863,45487,0,0,313,6627,0,0;QS=3,0;MQSB=0.0208913;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,12,97:4:0 0,15,148:5:0 +X 252 . G <*> 0 . DP=18;I16=8,9,0,0,641,24631,0,0,803,41887,0,0,304,6502,0,0;QS=3,0;MQSB=0.026526;MQ0F=0 PL:DP:DV 0,27,243:9:0 0,12,91:4:0 0,12,121:4:0 +X 253 . C <*> 0 . DP=19;I16=9,10,0,0,705,26921,0,0,892,46328,0,0,319,6687,0,0;QS=3,0;MQSB=0.0132999;MQ0F=0 PL:DP:DV 0,27,247:9:0 0,12,86:4:0 0,18,155:6:0 +X 254 . T <*> 0 . DP=20;I16=10,9,0,0,719,27517,0,0,892,46328,0,0,314,6670,0,0;QS=3,0;MQSB=0.00482795;MQ0F=0 PL:DP:DV 0,30,254:10:0 0,9,72:3:0 0,18,164:6:0 +X 255 . T <*> 0 . DP=21;I16=11,10,0,0,750,27076,0,0,1012,53528,0,0,328,6840,0,0;QS=3,0;MQSB=0.00822975;MQ0F=0 PL:DP:DV 0,33,241:11:0 0,12,95:4:0 0,18,161:6:0 +X 256 . A <*> 0 . DP=22;I16=11,11,0,0,811,30063,0,0,1049,54897,0,0,334,6956,0,0;QS=3,0;MQSB=0.00507916;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,110:5:0 0,18,166:6:0 +X 257 . T <*> 0 . DP=22;I16=11,11,0,0,814,30420,0,0,1049,54897,0,0,341,7101,0,0;QS=3,0;MQSB=0.00507916;MQ0F=0 PL:DP:DV 0,33,247:11:0 0,15,113:5:0 0,18,168:6:0 +X 258 . T <*> 0 . DP=22;I16=11,11,0,0,791,28943,0,0,1049,54897,0,0,347,7225,0,0;QS=3,0;MQSB=0.00507916;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,15,116:5:0 0,18,155:6:0 +X 259 . C <*> 0 . DP=22;I16=11,10,0,0,785,29809,0,0,1020,54056,0,0,332,6936,0,0;QS=3,0;MQSB=0.00822975;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,90:4:0 0,18,170:6:0 +X 260 . T <*> 0 . DP=21;I16=10,11,0,0,829,32899,0,0,989,51297,0,0,360,7556,0,0;QS=3,0;MQSB=0.00660016;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,118:5:0 0,15,156:5:0 +X 261 . G <*> 0 . DP=21;I16=10,11,0,0,735,27379,0,0,989,51297,0,0,367,7761,0,0;QS=3,0;MQSB=0.00660016;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,15,111:5:0 0,15,122:5:0 +X 262 . C <*> 0 . DP=22;I16=10,12,0,0,806,30278,0,0,1049,54897,0,0,373,7941,0,0;QS=3,0;MQSB=0.0122507;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,99:5:0 0,18,164:6:0 +X 263 . C <*> 0 . DP=22;I16=10,12,0,0,799,29717,0,0,1049,54897,0,0,380,8146,0,0;QS=3,0;MQSB=0.0122507;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,98:5:0 0,18,168:6:0 +X 264 . C <*> 0 . DP=22;I16=10,12,0,0,821,31325,0,0,1049,54897,0,0,386,8326,0,0;QS=3,0;MQSB=0.0122507;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,104:5:0 0,18,172:6:0 +X 265 . A <*> 0 . DP=21;I16=9,12,0,0,800,31906,0,0,989,51297,0,0,390,8380,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,114:5:0 0,15,129:5:0 +X 266 . G <*> 0 . DP=21;I16=9,11,0,0,747,28155,0,0,960,50456,0,0,369,7833,0,0;QS=3,0;MQSB=0.0237479;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,97:4:0 0,15,138:5:0 +X 267 . T <*> 0 . DP=21;I16=9,11,0,0,739,27465,0,0,960,50456,0,0,373,7935,0,0;QS=3,0;MQSB=0.0237479;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,12,101:4:0 0,15,149:5:0 +X 268 . T <*> 0 . DP=21;I16=9,12,0,0,748,27708,0,0,989,51297,0,0,402,8686,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:DV 0,33,238:11:0 0,15,110:5:0 0,15,156:5:0 +X 269 . C <*> 0 . DP=22;I16=9,12,0,0,764,28632,0,0,989,51297,0,0,381,8211,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,91:4:0 0,15,154:5:0 +X 270 . C <*> 0 . DP=22;I16=9,12,0,0,758,28146,0,0,989,51297,0,0,385,8337,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,96:4:0 0,15,143:5:0 +X 271 . T <*> 0 . DP=22;I16=9,13,0,0,847,32935,0,0,1018,52138,0,0,413,9065,0,0;QS=3,0;MQSB=0.0109431;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,113:5:0 0,15,152:5:0 +X 272 . C <*> 0 . DP=22;I16=9,12,0,0,809,31413,0,0,989,51297,0,0,390,8518,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,96:4:0 0,15,149:5:0 +X 273 . T <*> 0 . DP=22;I16=9,12,0,0,798,30664,0,0,989,51297,0,0,392,8620,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,95:4:0 0,15,161:5:0 +X 274 . C <*> 0 . DP=22;I16=9,12,0,0,763,28177,0,0,989,51297,0,0,394,8746,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,101:4:0 0,15,144:5:0 +X 275 . C <*> 0 . DP=20;I16=7,13,0,0,768,29994,0,0,898,44938,0,0,423,9519,0,0;QS=3,0;MQSB=0.0213617;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,114:5:0 0,12,122:4:0 +X 276 . A <*> 0 . DP=20;I16=7,13,0,0,805,32931,0,0,898,44938,0,0,424,9538,0,0;QS=3,0;MQSB=0.0213617;MQ0F=0 PL:DP:DV 0,33,253:11:0 0,15,122:5:0 0,12,124:4:0 +X 277 . G <*> 0 . DP=20;I16=7,13,0,0,764,29732,0,0,898,44938,0,0,425,9579,0,0;QS=3,0;MQSB=0.0213617;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,114:5:0 0,12,121:4:0 +X 278 . A <*> 0 . DP=21;I16=6,14,0,0,722,26452,0,0,867,42179,0,0,415,9521,0,0;QS=3,0;MQSB=0.0246228;MQ0F=0 PL:DP:DV 0,30,238:10:0 0,18,123:6:0 0,12,121:4:0 +X 279 . A <*> 0 . DP=22;I16=7,15,0,0,786,28694,0,0,956,46620,0,0,427,9677,0,0;QS=3,0;MQSB=0.0124927;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,123:6:0 0,12,122:4:0 +X 280 . A <*> 0 . DP=22;I16=7,15,0,0,815,31561,0,0,956,46620,0,0,428,9684,0,0;QS=3,0;MQSB=0.0124927;MQ0F=0 PL:DP:DV 0,36,253:12:0 0,18,130:6:0 0,12,129:4:0 +X 281 . G <*> 0 . DP=22;I16=7,15,0,0,820,31416,0,0,956,46620,0,0,428,9662,0,0;QS=3,0;MQSB=0.0124927;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,122:6:0 0,12,123:4:0 +X 282 . G <*> 0 . DP=22;I16=7,15,0,0,806,30420,0,0,956,46620,0,0,427,9609,0,0;QS=3,0;MQSB=0.0124927;MQ0F=0 PL:DP:DV 0,36,253:12:0 0,18,124:6:0 0,12,119:4:0 +X 283 . C <*> 0 . DP=23;I16=7,15,0,0,827,31785,0,0,956,46620,0,0,426,9574,0,0;QS=3,0;MQSB=0.0124927;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,125:6:0 0,12,122:4:0 +X 284 . T <*> 0 . DP=23;I16=7,16,0,0,901,35479,0,0,1016,50220,0,0,431,9593,0,0;QS=3,0;MQSB=0.0194969;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,126:6:0 0,15,144:5:0 +X 285 . G <*> 0 . DP=23;I16=7,16,0,0,860,32856,0,0,1016,50220,0,0,431,9607,0,0;QS=3,0;MQSB=0.0194969;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,119:6:0 0,15,132:5:0 +X 286 . C <*> 0 . DP=24;I16=8,16,0,0,875,32883,0,0,1076,53820,0,0,431,9641,0,0;QS=3,0;MQSB=0.0132999;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,150:7:0 0,15,134:5:0 +X 287 . A <*> 0 . DP=25;I16=9,16,0,0,895,32957,0,0,1136,57420,0,0,432,9696,0,0;QS=3,0;MQSB=0.00934348;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,178:8:0 0,15,133:5:0 +X 288 . T <*> 0 . DP=25;I16=9,16,0,0,931,35011,0,0,1136,57420,0,0,432,9674,0,0;QS=3,0;MQSB=0.00934348;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,184:8:0 0,15,146:5:0 +X 289 . G <*> 0 . DP=25;I16=9,16,0,0,939,36117,0,0,1136,57420,0,0,432,9676,0,0;QS=3,0;MQSB=0.00934348;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,185:8:0 0,15,136:5:0 +X 290 . G <*> 0 . DP=23;I16=8,15,0,0,805,29157,0,0,1047,52979,0,0,433,9651,0,0;QS=3,0;MQSB=0.0177152;MQ0F=0 PL:DP:DV 0,33,240:11:0 0,21,164:7:0 0,15,126:5:0 +X 291 . T <*> 0 . DP=24;I16=8,15,0,0,840,31616,0,0,1047,52979,0,0,421,9479,0,0;QS=3,0;MQSB=0.0177152;MQ0F=0 PL:DP:DV 0,33,244:11:0 0,21,168:7:0 0,15,136:5:0 +X 292 . T <*> 0 . DP=25;I16=9,16,0,0,888,32274,0,0,1167,60179,0,0,436,9668,0,0;QS=3,0;MQSB=0.0197089;MQ0F=0 PL:DP:DV 0,33,253:11:0 0,24,181:8:0 0,18,156:6:0 +X 293 . G <*> 0 . DP=26;I16=10,15,0,0,934,35232,0,0,1167,60179,0,0,424,9488,0,0;QS=3,0;MQSB=0.0095249;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,196:8:0 0,15,145:5:0 +X 294 . A <*> 0 . DP=26;I16=10,16,0,0,931,33937,0,0,1227,63779,0,0,443,9785,0,0;QS=3,0;MQSB=0.0149748;MQ0F=0 PL:DP:DV 0,36,252:12:0 0,24,201:8:0 0,18,161:6:0 +X 295 . C <*> 0 . DP=25;I16=10,14,0,0,897,33973,0,0,1169,62097,0,0,430,9544,0,0;QS=3,0;MQSB=0.0310726;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,180:7:0 0,18,159:6:0 +X 296 . A <*> 0 . DP=25;I16=10,15,0,0,874,31846,0,0,1198,62938,0,0,451,9905,0,0;QS=3,0;MQSB=0.0213617;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,169:8:0 0,18,169:6:0 +X 297 . C <*> 0 . DP=25;I16=9,15,0,0,901,34305,0,0,1138,59338,0,0,445,9901,0,0;QS=3,0;MQSB=0.0273237;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,174:7:0 0,18,161:6:0 +X 298 . A <*> 0 . DP=26;I16=11,15,0,0,936,34652,0,0,1258,66538,0,0,459,10121,0,0;QS=3,0;MQSB=0.017008;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,184:8:0 0,21,191:7:0 +X 299 . C <*> 0 . DP=27;I16=11,15,0,0,971,36863,0,0,1258,66538,0,0,464,10266,0,0;QS=3,0;MQSB=0.017008;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,193:8:0 0,21,189:7:0 +X 300 . A <*> 0 . DP=27;I16=11,15,0,0,1001,39455,0,0,1258,66538,0,0,469,10437,0,0;QS=3,0;MQSB=0.017008;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,204:8:0 0,21,210:7:0 +X 301 . G <*> 0 . DP=25;I16=10,14,0,0,928,36116,0,0,1169,62097,0,0,476,10632,0,0;QS=3,0;MQSB=0.0310726;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,195:7:0 0,21,196:7:0 +X 302 . T <*> 0 . DP=25;I16=10,14,0,0,879,32885,0,0,1169,62097,0,0,483,10849,0,0;QS=3,0;MQSB=0.0310726;MQ0F=0 PL:DP:DV 0,30,231:10:0 0,21,172:7:0 0,21,202:7:0 +X 302 . T TA 0 . INDEL;IDV=7;IMF=1;DP=25;I16=2,4,8,11,214,7674,793,33369,236,10564,993,55133,109,2229,377,8629;QS=0.511212,2.48879;VDB=0.27613;SGB=-4.22417;MQSB=0.0443614;MQ0F=0 PL:DP:DV 167,0,96:11:6 157,0,9:7:6 201,21,0:7:7 +X 303 . G <*> 0 . DP=25;I16=10,15,0,0,976,38516,0,0,1229,65697,0,0,497,11181,0,0;QS=3,0;MQSB=0.0443614;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,197:7:0 0,21,195:7:0 +X 304 . C <*> 0 . DP=27;I16=11,16,0,0,991,37005,0,0,1318,70138,0,0,503,11359,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,206:8:0 0,24,200:8:0 +X 305 . C <*> 0 . DP=27;I16=11,16,0,0,1057,41761,0,0,1318,70138,0,0,510,11508,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,213:8:0 0,24,211:8:0 +X 306 . T <*> 0 . DP=27;I16=11,16,0,0,1033,40253,0,0,1318,70138,0,0,517,11679,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,207:8:0 0,24,217:8:0 +X 307 . G <*> 0 . DP=27;I16=11,15,0,0,984,37886,0,0,1289,69297,0,0,498,11198,0,0;QS=3,0;MQSB=0.174566;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,189:7:0 0,24,203:8:0 +X 308 . C <*> 0 . DP=27;I16=11,16,0,0,892,30810,0,0,1318,70138,0,0,529,11991,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,178:8:0 0,24,185:8:0 +X 309 . G <*> 0 . DP=27;I16=11,16,0,0,951,34599,0,0,1318,70138,0,0,535,12183,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:DV 0,33,243:11:0 0,24,183:8:0 0,24,205:8:0 +X 310 . A <*> 0 . DP=27;I16=11,16,0,0,1001,38063,0,0,1318,70138,0,0,540,12350,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,200:8:0 0,24,217:8:0 +X 311 . C <*> 0 . DP=27;I16=11,16,0,0,1037,40263,0,0,1318,70138,0,0,544,12492,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,215:8:0 0,24,210:8:0 +X 312 . A <*> 0 . DP=26;I16=10,16,0,0,985,38043,0,0,1258,66538,0,0,549,12657,0,0;QS=3,0;MQSB=0.157183;MQ0F=0 PL:DP:DV 0,30,237:10:0 0,24,215:8:0 0,24,218:8:0 +X 313 . A <*> 0 . DP=26;I16=10,16,0,0,983,37969,0,0,1258,66538,0,0,551,12695,0,0;QS=3,0;MQSB=0.157183;MQ0F=0 PL:DP:DV 0,30,235:10:0 0,24,219:8:0 0,24,215:8:0 +X 314 . A <*> 0 . DP=27;I16=10,17,0,0,1050,41798,0,0,1318,70138,0,0,553,12757,0,0;QS=3,0;MQSB=0.195223;MQ0F=0 PL:DP:DV 0,33,250:11:0 0,24,217:8:0 0,24,227:8:0 +X 315 . G <*> 0 . DP=26;I16=10,16,0,0,1025,40941,0,0,1289,69297,0,0,557,12843,0,0;QS=3,0;MQSB=0.252051;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,24,216:8:0 0,24,225:8:0 +X 316 . C <*> 0 . DP=27;I16=10,15,0,0,983,39393,0,0,1252,67928,0,0,535,12277,0,0;QS=3,0;MQSB=0.312403;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,183:7:0 0,24,224:8:0 +X 317 . T <*> 0 . DP=27;I16=10,16,0,0,1028,41392,0,0,1320,72056,0,0,547,12557,0,0;QS=3,0;MQSB=0.377061;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,230:8:0 0,24,206:8:0 +X 318 . G <*> 0 . DP=27;I16=10,17,0,0,1038,40546,0,0,1349,72897,0,0,570,13018,0,0;QS=3,0;MQSB=0.297797;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,27,235:9:0 0,24,208:8:0 +X 319 . A <*> 0 . DP=27;I16=9,17,0,0,994,38654,0,0,1289,69297,0,0,560,12906,0,0;QS=3,0;MQSB=0.346864;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,27,228:9:0 0,21,185:7:0 +X 320 . A <*> 0 . DP=27;I16=10,17,0,0,1022,39418,0,0,1349,72897,0,0,573,13053,0,0;QS=3,0;MQSB=0.297797;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,27,230:9:0 0,24,211:8:0 +X 321 . T <*> 0 . DP=27;I16=10,17,0,0,1026,39772,0,0,1349,72897,0,0,573,13029,0,0;QS=3,0;MQSB=0.297797;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,27,214:9:0 0,24,218:8:0 +X 322 . G <*> 0 . DP=28;I16=10,18,0,0,1091,43151,0,0,1409,76497,0,0,573,13029,0,0;QS=3,0;MQSB=0.343265;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,27,226:9:0 0,27,223:9:0 +X 323 . C <*> 0 . DP=28;I16=9,18,0,0,1067,42619,0,0,1349,72897,0,0,565,12939,0,0;QS=3,0;MQSB=0.394987;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,27,225:9:0 0,24,198:8:0 +X 324 . T <*> 0 . DP=30;I16=12,18,0,0,1145,44221,0,0,1529,83697,0,0,573,13001,0,0;QS=3,0;MQSB=0.264959;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,27,237:9:0 0,33,255:11:0 +X 325 . A <*> 0 . DP=31;I16=13,18,0,0,1132,42058,0,0,1589,87297,0,0,573,12925,0,0;QS=3,0;MQSB=0.235201;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,208:9:0 0,33,255:11:0 +X 326 . T <*> 0 . DP=31;I16=13,18,0,0,1157,44193,0,0,1589,87297,0,0,574,12878,0,0;QS=3,0;MQSB=0.235201;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,216:9:0 0,33,255:11:0 +X 327 . C <*> 0 . DP=31;I16=13,18,0,0,1147,43895,0,0,1589,87297,0,0,575,12861,0,0;QS=3,0;MQSB=0.235201;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,198:9:0 0,33,255:11:0 +X 328 . A <*> 0 . DP=31;I16=13,18,0,0,1167,44531,0,0,1589,87297,0,0,574,12776,0,0;QS=3,0;MQSB=0.235201;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,226:9:0 0,33,255:11:0 +X 329 . T <*> 0 . DP=31;I16=13,18,0,0,1210,47742,0,0,1589,87297,0,0,572,12676,0,0;QS=3,0;MQSB=0.235201;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,237:9:0 0,33,255:11:0 +X 330 . T <*> 0 . DP=31;I16=13,18,0,0,1185,45839,0,0,1589,87297,0,0,568,12510,0,0;QS=3,0;MQSB=0.235201;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,27,231:9:0 0,33,255:11:0 +X 331 . T <*> 0 . DP=32;I16=14,18,0,0,1154,42510,0,0,1649,90897,0,0,563,12327,0,0;QS=3,0;MQSB=0.210122;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,222:9:0 0,36,255:12:0 +X 332 . A <*> 0 . DP=32;I16=14,18,0,0,1156,42666,0,0,1649,90897,0,0,560,12178,0,0;QS=3,0;MQSB=0.210122;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,214:9:0 0,33,255:11:0 +X 333 . A <*> 0 . DP=32;I16=14,18,0,0,1141,41987,0,0,1649,90897,0,0,558,12064,0,0;QS=3,0;MQSB=0.210122;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,223:9:0 0,33,255:11:0 +X 334 . A <*> 0 . DP=32;I16=14,18,0,0,1162,43328,0,0,1649,90897,0,0,556,11986,0,0;QS=3,0;MQSB=0.210122;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,221:9:0 0,33,255:11:0 +X 335 . A <*> 0 . DP=32;I16=12,18,0,0,1077,40287,0,0,1529,83697,0,0,552,11934,0,0;QS=3,0;MQSB=0.264959;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,27,219:9:0 0,33,251:11:0 +X 336 . A <*> 0 . DP=32;I16=14,17,0,0,1088,39758,0,0,1612,89528,0,0,536,11574,0,0;QS=3,0;MQSB=0.274662;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,211:8:0 0,36,255:12:0 +X 337 . C <*> 0 . DP=32;I16=13,17,0,0,1115,42381,0,0,1552,85928,0,0,531,11565,0,0;QS=3,0;MQSB=0.301511;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,202:8:0 0,36,255:12:0 +X 338 . T <*> 0 . DP=30;I16=14,16,0,0,1191,47979,0,0,1560,86456,0,0,554,11878,0,0;QS=3,0;MQSB=0.242376;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,226:8:0 0,36,255:12:0 +X 339 . C <*> 0 . DP=31;I16=14,17,0,0,1130,43210,0,0,1589,87297,0,0,554,11874,0,0;QS=3,0;MQSB=0.175471;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,185:8:0 0,36,255:12:0 +X 340 . C <*> 0 . DP=31;I16=14,17,0,0,1196,47044,0,0,1589,87297,0,0,554,11852,0,0;QS=3,0;MQSB=0.175471;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,221:8:0 0,36,255:12:0 +X 341 . T <*> 0 . DP=31;I16=14,17,0,0,1227,48995,0,0,1589,87297,0,0,554,11862,0,0;QS=3,0;MQSB=0.175471;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,216:8:0 0,36,255:12:0 +X 342 . T <*> 0 . DP=31;I16=14,17,0,0,1162,43942,0,0,1589,87297,0,0,554,11904,0,0;QS=3,0;MQSB=0.175471;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,210:8:0 0,36,255:12:0 +X 343 . G <*> 0 . DP=32;I16=14,17,0,0,1150,43702,0,0,1620,90056,0,0,550,11962,0,0;QS=3,0;MQSB=0.283511;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,27,218:9:0 0,36,255:12:0 +X 344 . C <*> 0 . DP=32;I16=14,18,0,0,1181,45169,0,0,1649,90897,0,0,554,12036,0,0;QS=3,0;MQSB=0.210122;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,217:9:0 0,36,255:12:0 +X 345 . T <*> 0 . DP=31;I16=14,17,0,0,1205,47259,0,0,1589,87297,0,0,555,12129,0,0;QS=3,0;MQSB=0.175471;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,221:8:0 0,36,255:12:0 +X 346 . G <*> 0 . DP=31;I16=15,16,0,0,1147,43597,0,0,1620,90056,0,0,557,12255,0,0;QS=3,0;MQSB=0.220358;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,212:8:0 0,36,255:12:0 +X 347 . G <*> 0 . DP=31;I16=14,16,0,0,1119,42227,0,0,1560,86456,0,0,545,12189,0,0;QS=3,0;MQSB=0.242376;MQ0F=0 PL:DP:DV 0,30,251:10:0 0,24,207:8:0 0,36,255:12:0 +X 348 . T <*> 0 . DP=32;I16=15,16,0,0,1145,43007,0,0,1620,90056,0,0,546,12300,0,0;QS=3,0;MQSB=0.220358;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,27,228:9:0 0,36,255:12:0 +X 349 . T <*> 0 . DP=32;I16=16,16,0,0,1194,45350,0,0,1680,93656,0,0,565,12731,0,0;QS=3,0;MQSB=0.201402;MQ0F=0 PL:DP:DV 0,33,246:11:0 0,27,230:9:0 0,36,255:12:0 +X 350 . T <*> 0 . DP=31;I16=16,15,0,0,1142,43072,0,0,1651,92815,0,0,567,12837,0,0;QS=3,0;MQSB=0.286505;MQ0F=0 PL:DP:DV 0,33,249:11:0 0,27,230:9:0 0,33,255:11:0 +X 351 . G <*> 0 . DP=31;I16=16,15,0,0,1146,43750,0,0,1651,92815,0,0,568,12920,0,0;QS=3,0;MQSB=0.286505;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,212:9:0 0,33,255:11:0 +X 352 . A <*> 0 . DP=31;I16=16,14,0,0,1150,45520,0,0,1591,89215,0,0,544,12404,0,0;QS=3,0;MQSB=0.242376;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,224:8:0 0,33,255:11:0 +X 353 . G <*> 0 . DP=29;I16=15,14,0,0,1109,43095,0,0,1562,88374,0,0,570,13064,0,0;QS=3,0;MQSB=0.424373;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,27,231:9:0 0,30,255:10:0 +X 354 . A <*> 0 . DP=28;I16=14,14,0,0,1078,42938,0,0,1502,84774,0,0,571,13075,0,0;QS=3,0;MQSB=0.450096;MQ0F=0 PL:DP:DV 0,27,225:9:0 0,27,244:9:0 0,30,255:10:0 +X 355 . G T,<*> 0 . DP=28;I16=14,13,0,1,1001,37907,41,1681,1442,81174,60,3600,547,12487,25,625;QS=2.875,0.125,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.450096;BQB=1;MQ0F=0 PL:DP:DV 14,0,200,38,203,231:9:1 0,27,222,27,222,222:9:0 0,30,255,30,255,255:10:0 +X 356 . G <*> 0 . DP=27;I16=14,13,0,0,993,37481,0,0,1465,83405,0,0,574,13174,0,0;QS=3,0;MQSB=0.580277;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,24,201:8:0 0,30,255:10:0 +X 357 . C <*> 0 . DP=28;I16=14,13,0,0,1021,39471,0,0,1465,83405,0,0,550,12584,0,0;QS=3,0;MQSB=0.580277;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,205:8:0 0,27,251:9:0 +X 358 . A <*> 0 . DP=28;I16=15,13,0,0,1050,40518,0,0,1525,87005,0,0,576,13216,0,0;QS=3,0;MQSB=0.556581;MQ0F=0 PL:DP:DV 0,30,254:10:0 0,24,197:8:0 0,30,255:10:0 +X 359 . G <*> 0 . DP=29;I16=15,13,0,0,1085,42761,0,0,1525,87005,0,0,552,12620,0,0;QS=3,0;MQSB=0.556581;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,187:7:0 0,33,255:11:0 +X 360 . A <*> 0 . DP=29;I16=15,14,0,0,1111,43259,0,0,1585,90605,0,0,579,13297,0,0;QS=3,0;MQSB=0.604224;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,24,220:8:0 0,33,255:11:0 +X 361 . A <*> 0 . DP=29;I16=15,14,0,0,1116,43442,0,0,1585,90605,0,0,579,13273,0,0;QS=3,0;MQSB=0.604224;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,24,219:8:0 0,33,255:11:0 +X 362 . A <*> 0 . DP=29;I16=16,13,0,0,1104,42700,0,0,1585,90605,0,0,580,13272,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,218:8:0 0,30,255:10:0 +X 363 . A <*> 0 . DP=29;I16=16,13,0,0,1087,41437,0,0,1585,90605,0,0,581,13245,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,213:8:0 0,30,255:10:0 +X 364 . T <*> 0 . DP=29;I16=16,13,0,0,1032,37960,0,0,1585,90605,0,0,582,13244,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:DV 0,33,250:11:0 0,24,205:8:0 0,30,255:10:0 +X 365 . G <*> 0 . DP=29;I16=16,13,0,0,1105,43079,0,0,1585,90605,0,0,582,13218,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,211:8:0 0,30,255:10:0 +X 366 . A <*> 0 . DP=29;I16=16,13,0,0,1090,41562,0,0,1585,90605,0,0,581,13167,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,211:8:0 0,30,255:10:0 +X 367 . T <*> 0 . DP=29;I16=16,13,0,0,1055,39149,0,0,1585,90605,0,0,579,13093,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,204:8:0 0,30,255:10:0 +X 368 . A <*> 0 . DP=29;I16=16,13,0,0,1054,39632,0,0,1585,90605,0,0,576,12998,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,208:8:0 0,30,255:10:0 +X 369 . T <*> 0 . DP=28;I16=16,11,0,0,1037,40275,0,0,1496,86164,0,0,548,12256,0,0;QS=3,0;MQSB=0.659218;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,21,196:7:0 0,30,255:10:0 +X 370 . C <*> 0 . DP=28;I16=16,12,0,0,1045,40219,0,0,1556,89764,0,0,570,12790,0,0;QS=3,0;MQSB=0.705296;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,201:8:0 0,30,255:10:0 +X 371 . T <*> 0 . DP=29;I16=16,13,0,0,1155,46591,0,0,1616,93364,0,0,567,12725,0,0;QS=3,0;MQSB=0.744925;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,227:8:0 0,33,255:11:0 +X 372 . C <*> 0 . DP=30;I16=16,14,0,0,1139,44019,0,0,1676,96964,0,0,564,12636,0,0;QS=3,0;MQSB=0.779025;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,215:8:0 0,33,255:11:0 +X 373 . A <*> 0 . DP=30;I16=16,14,0,0,1142,44118,0,0,1676,96964,0,0,561,12525,0,0;QS=3,0;MQSB=0.779025;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,220:8:0 0,33,255:11:0 +X 374 . T <*> 0 . DP=30;I16=16,14,0,0,1098,41180,0,0,1676,96964,0,0,556,12344,0,0;QS=3,0;MQSB=0.779025;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,221:8:0 0,33,255:11:0 +X 375 . A T,<*> 0 . DP=31;I16=17,13,0,1,1138,43798,14,196,1676,96964,60,3600,547,12177,4,16;QS=2.9661,0.0338983,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.763662;BQB=1;MQ0F=0 PL:DP:DV 0,36,255,36,255,255:12:0 0,24,218,24,218,218:8:0 0,18,255,30,255,255:11:1 +X 376 . G <*> 0 . DP=31;I16=17,14,0,0,1131,42581,0,0,1736,100564,0,0,547,12073,0,0;QS=3,0;MQSB=0.763662;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,220:8:0 0,33,255:11:0 +X 377 . T <*> 0 . DP=31;I16=16,14,0,0,1105,41629,0,0,1676,96964,0,0,518,11360,0,0;QS=3,0;MQSB=0.779025;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,211:8:0 0,33,255:11:0 +X 378 . T <*> 0 . DP=30;I16=18,12,0,0,1098,41066,0,0,1707,99723,0,0,541,11927,0,0;QS=3,0;MQSB=0.878946;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,186:7:0 0,30,255:10:0 +X 379 . G <*> 0 . DP=29;I16=18,10,0,0,1053,40181,0,0,1618,95282,0,0,534,11848,0,0;QS=3,0;MQSB=0.981777;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,187:7:0 0,30,255:10:0 +X 380 . C <*> 0 . DP=29;I16=18,10,0,0,1087,42743,0,0,1618,95282,0,0,514,11172,0,0;QS=3,0;MQSB=0.981777;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,177:6:0 0,30,255:10:0 +X 381 . T <*> 0 . DP=29;I16=18,11,0,0,1168,47412,0,0,1678,98882,0,0,537,11729,0,0;QS=3,0;MQSB=0.987702;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,212:7:0 0,30,255:10:0 +X 382 . T <*> 0 . DP=29;I16=17,11,0,0,1054,40450,0,0,1618,95282,0,0,510,11068,0,0;QS=3,0;MQSB=0.990092;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,182:7:0 0,30,255:10:0 +X 383 . T <*> 0 . DP=29;I16=18,10,0,0,1052,39798,0,0,1618,95282,0,0,507,11013,0,0;QS=3,0;MQSB=0.981777;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,165:6:0 0,30,255:10:0 +X 384 . A <*> 0 . DP=31;I16=19,11,0,0,1077,39885,0,0,1738,102482,0,0,504,10988,0,0;QS=3,0;MQSB=0.985292;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,176:7:0 0,30,255:10:0 +X 385 . C <*> 0 . DP=31;I16=19,12,0,0,1118,41180,0,0,1798,106082,0,0,527,11569,0,0;QS=3,0;MQSB=0.989977;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,186:8:0 0,30,255:10:0 +X 386 . T <*> 0 . DP=30;I16=18,12,0,0,1158,45592,0,0,1738,102482,0,0,526,11556,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,191:7:0 0,30,255:10:0 +X 387 . T <*> 0 . DP=30;I16=18,12,0,0,1105,41821,0,0,1738,102482,0,0,525,11573,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,187:7:0 0,30,255:10:0 +X 388 . T <*> 0 . DP=29;I16=17,12,0,0,1089,41577,0,0,1678,98882,0,0,523,11519,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,180:6:0 0,30,255:10:0 +X 389 . G <*> 0 . DP=29;I16=17,12,0,0,1067,40095,0,0,1678,98882,0,0,520,11444,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,171:6:0 0,30,255:10:0 +X 390 . C <*> 0 . DP=29;I16=17,12,0,0,1071,40423,0,0,1678,98882,0,0,517,11399,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,162:6:0 0,30,255:10:0 +X 391 . A <*> 0 . DP=29;I16=18,11,0,0,1091,41603,0,0,1647,96123,0,0,515,11383,0,0;QS=3,0;MQSB=0.995968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,163:6:0 0,30,255:10:0 +X 392 . T <*> 0 . DP=29;I16=18,11,0,0,1046,38838,0,0,1647,96123,0,0,515,11395,0,0;QS=3,0;MQSB=0.995968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,153:5:0 0,33,255:11:0 +X 393 . A <*> 0 . DP=28;I16=17,11,0,0,1014,37582,0,0,1587,92523,0,0,517,11435,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,133:5:0 0,33,255:11:0 +X 394 . T <*> 0 . DP=28;I16=17,11,0,0,1022,38342,0,0,1587,92523,0,0,519,11503,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,141:5:0 0,33,255:11:0 +X 395 . T <*> 0 . DP=28;I16=17,11,0,0,1060,40596,0,0,1587,92523,0,0,521,11599,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,164:5:0 0,33,255:11:0 +X 396 . T <*> 0 . DP=28;I16=17,11,0,0,1032,39228,0,0,1587,92523,0,0,523,11723,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,158:5:0 0,33,255:11:0 +X 397 . T <*> 0 . DP=28;I16=17,11,0,0,1046,39510,0,0,1587,92523,0,0,524,11824,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,149:5:0 0,33,255:11:0 +X 398 . A <*> 0 . DP=28;I16=17,11,0,0,1021,38105,0,0,1587,92523,0,0,524,11850,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,144:5:0 0,30,255:10:0 +X 399 . A <*> 0 . DP=28;I16=17,11,0,0,1015,38469,0,0,1587,92523,0,0,526,11900,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,140:5:0 0,30,255:10:0 +X 400 . A <*> 0 . DP=29;I16=17,12,0,0,1056,39702,0,0,1647,96123,0,0,526,11828,0,0;QS=3,0;MQSB=0.988062;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,159:5:0 0,33,255:11:0 +X 401 . A <*> 0 . DP=29;I16=17,11,0,0,1052,40302,0,0,1587,92523,0,0,501,11113,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,160:5:0 0,30,255:10:0 +X 402 . T <*> 0 . DP=29;I16=17,12,0,0,1082,41232,0,0,1647,96123,0,0,526,11680,0,0;QS=3,0;MQSB=0.988062;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,149:5:0 0,33,255:11:0 +X 403 . T <*> 0 . DP=29;I16=17,12,0,0,1085,40985,0,0,1647,96123,0,0,526,11654,0,0;QS=3,0;MQSB=0.988062;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,148:5:0 0,33,255:11:0 +X 404 . G <*> 0 . DP=29;I16=17,12,0,0,1074,40524,0,0,1647,96123,0,0,525,11609,0,0;QS=3,0;MQSB=0.988062;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,131:5:0 0,33,255:11:0 +X 405 . T <*> 0 . DP=27;I16=16,10,0,0,988,37870,0,0,1498,88082,0,0,519,11543,0,0;QS=3,0;MQSB=0.987578;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,103:3:0 0,30,255:10:0 +X 406 . G <*> 0 . DP=27;I16=16,11,0,0,976,36752,0,0,1558,91682,0,0,527,11601,0,0;QS=3,0;MQSB=0.992419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,125:4:0 0,30,247:10:0 +X 407 . A <*> 0 . DP=27;I16=16,11,0,0,1007,38355,0,0,1558,91682,0,0,526,11538,0,0;QS=3,0;MQSB=0.992419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,125:4:0 0,30,255:10:0 +X 408 . C <*> 0 . DP=28;I16=16,11,0,0,1006,38136,0,0,1558,91682,0,0,521,11489,0,0;QS=3,0;MQSB=0.992419;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,110:3:0 0,30,244:10:0 +X 409 . T <*> 0 . DP=29;I16=17,12,0,0,1100,42734,0,0,1678,98882,0,0,525,11503,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,131:4:0 0,33,255:11:0 +X 410 . T <*> 0 . DP=29;I16=17,12,0,0,1035,38325,0,0,1678,98882,0,0,524,11432,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,125:4:0 0,33,255:11:0 +X 411 . T <*> 0 . DP=29;I16=17,10,0,0,1003,37747,0,0,1558,91682,0,0,496,10716,0,0;QS=3,0;MQSB=0.984677;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,104:3:0 0,30,255:10:0 +X 412 . C T,<*> 0 . DP=30;I16=17,12,1,0,1094,42458,14,196,1678,98882,60,3600,495,10659,25,625;QS=2.97455,0.0254545,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.991968;BQB=1;MQ0F=0 PL:DP:DV 0,30,255,42,255,255:15:1 0,12,124,12,124,124:4:0 0,33,255,33,255,255:11:0 +X 413 . A <*> 0 . DP=31;I16=18,13,0,0,1189,45985,0,0,1798,106082,0,0,520,11258,0,0;QS=3,0;MQSB=0.995005;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,102:3:0 0,33,255:11:0 +X 414 . T <*> 0 . DP=30;I16=18,12,0,0,1151,44355,0,0,1738,102482,0,0,523,11265,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,109:3:0 0,33,255:11:0 +X 415 . G <*> 0 . DP=30;I16=18,12,0,0,1131,43175,0,0,1738,102482,0,0,526,11306,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,110:3:0 0,33,255:11:0 +X 416 . G <*> 0 . DP=30;I16=17,12,0,0,1083,41273,0,0,1678,98882,0,0,514,11156,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,114:3:0 0,30,253:10:0 +X 417 . C <*> 0 . DP=30;I16=18,12,0,0,1114,42244,0,0,1738,102482,0,0,531,11439,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,108:3:0 0,33,255:11:0 +X 418 . A <*> 0 . DP=30;I16=18,12,0,0,1146,44248,0,0,1738,102482,0,0,532,11478,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,111:3:0 0,33,255:11:0 +X 419 . T <*> 0 . DP=30;I16=18,12,0,0,1117,42327,0,0,1738,102482,0,0,532,11498,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,112:3:0 0,33,255:11:0 +X 420 . A <*> 0 . DP=31;I16=18,13,0,0,1117,41011,0,0,1798,106082,0,0,532,11550,0,0;QS=3,0;MQSB=0.995005;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,108:3:0 0,36,255:12:0 +X 421 . A <*> 0 . DP=33;I16=19,14,0,0,1208,45398,0,0,1887,110523,0,0,533,11635,0,0;QS=3,0;MQSB=0.986656;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,113:3:0 0,42,255:14:0 +X 422 . A <*> 0 . DP=33;I16=19,13,0,0,1205,46441,0,0,1827,106923,0,0,510,11082,0,0;QS=3,0;MQSB=0.991023;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,116:3:0 0,39,255:13:0 +X 423 . T <*> 0 . DP=32;I16=19,13,0,0,1202,45416,0,0,1827,106923,0,0,538,11818,0,0;QS=3,0;MQSB=0.991023;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,110:3:0 0,39,255:13:0 +X 424 . A <*> 0 . DP=32;I16=19,13,0,0,1147,41685,0,0,1827,106923,0,0,539,11867,0,0;QS=3,0;MQSB=0.991023;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,106:3:0 0,39,255:13:0 +X 425 . A <*> 0 . DP=29;I16=16,13,0,0,1070,40616,0,0,1647,96123,0,0,542,11900,0,0;QS=3,0;MQSB=0.976248;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,111:3:0 0,33,249:11:0 +X 426 . T <*> 0 . DP=29;I16=16,12,0,0,997,36561,0,0,1587,92523,0,0,519,11287,0,0;QS=3,0;MQSB=0.982906;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,105:3:0 0,30,225:10:0 +X 427 . A <*> 0 . DP=29;I16=16,13,0,0,1024,37266,0,0,1647,96123,0,0,546,11952,0,0;QS=3,0;MQSB=0.976248;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,111:3:0 0,33,242:11:0 +X 428 . C <*> 0 . DP=29;I16=16,13,0,0,1064,39706,0,0,1647,96123,0,0,548,12020,0,0;QS=3,0;MQSB=0.976248;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,111:3:0 0,33,254:11:0 +X 429 . T <*> 0 . DP=30;I16=16,14,0,0,1150,44918,0,0,1707,99723,0,0,549,12067,0,0;QS=3,0;MQSB=0.969373;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,115:3:0 0,33,255:11:0 +X 430 . G <*> 0 . DP=30;I16=16,14,0,0,1113,42443,0,0,1707,99723,0,0,551,12145,0,0;QS=3,0;MQSB=0.969373;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,112:3:0 0,33,246:11:0 +X 431 . G <*> 0 . DP=30;I16=14,14,0,0,1003,36953,0,0,1587,92523,0,0,553,12255,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,101:3:0 0,30,225:10:0 +X 432 . T <*> 0 . DP=28;I16=14,14,0,0,1049,39621,0,0,1587,92523,0,0,556,12346,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,114:3:0 0,30,255:10:0 +X 433 . T <*> 0 . DP=28;I16=14,12,0,0,949,35443,0,0,1467,85323,0,0,509,11217,0,0;QS=3,0;MQSB=0.967472;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,112:3:0 0,27,227:9:0 +X 434 . T <*> 0 . DP=29;I16=15,14,0,0,1036,37654,0,0,1647,96123,0,0,561,12567,0,0;QS=3,0;MQSB=0.960561;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,98:3:0 0,30,243:10:0 +X 435 . A <*> 0 . DP=29;I16=15,13,0,0,1024,37970,0,0,1587,92523,0,0,556,12560,0,0;QS=3,0;MQSB=0.968414;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,103:3:0 0,30,237:10:0 +X 436 . T <*> 0 . DP=28;I16=14,14,0,0,998,36220,0,0,1587,92523,0,0,564,12654,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,110:3:0 0,27,223:9:0 +X 437 . T <*> 0 . DP=28;I16=13,14,0,0,990,36832,0,0,1558,91682,0,0,549,12435,0,0;QS=3,0;MQSB=0.999706;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,109:3:0 0,24,207:8:0 +X 438 . A <*> 0 . DP=28;I16=14,13,0,0,972,35640,0,0,1527,88923,0,0,540,12082,0,0;QS=3,0;MQSB=0.9585;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,107:3:0 0,24,216:8:0 +X 439 . C <*> 0 . DP=28;I16=14,14,0,0,1055,40273,0,0,1587,92523,0,0,563,12649,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,107:3:0 0,27,224:9:0 +X 440 . A <*> 0 . DP=28;I16=14,14,0,0,1095,43251,0,0,1587,92523,0,0,561,12615,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,115:3:0 0,27,247:9:0 +X 441 . G <*> 0 . DP=29;I16=15,14,0,0,1068,40344,0,0,1647,96123,0,0,559,12605,0,0;QS=3,0;MQSB=0.960561;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,104:3:0 0,27,198:9:0 +X 442 . A <*> 0 . DP=29;I16=15,14,0,0,1091,41507,0,0,1647,96123,0,0,558,12620,0,0;QS=3,0;MQSB=0.960561;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,112:3:0 0,27,233:9:0 +X 443 . A <*> 0 . DP=30;I16=15,14,0,0,1173,49439,0,0,1647,96123,0,0,557,12661,0,0;QS=3,0;MQSB=0.960561;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,129:3:0 0,27,246:9:0 +X 444 . G <*> 0 . DP=29;I16=15,13,0,0,1095,44661,0,0,1587,92523,0,0,557,12727,0,0;QS=3,0;MQSB=0.968414;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,91:2:0 0,27,227:9:0 +X 445 . C <*> 0 . DP=30;I16=16,13,0,0,1100,43706,0,0,1647,96123,0,0,557,12817,0,0;QS=3,0;MQSB=0.976248;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,111:3:0 0,27,219:9:0 +X 446 . A <*> 0 . DP=30;I16=16,13,0,0,1107,44265,0,0,1647,96123,0,0,557,12881,0,0;QS=3,0;MQSB=0.976248;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,115:3:0 0,27,232:9:0 +X 447 . C <*> 0 . DP=29;I16=16,12,0,0,1108,45364,0,0,1618,95282,0,0,555,12817,0,0;QS=3,0;MQSB=0.856268;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,114:3:0 0,27,235:9:0 +X 448 . T <*> 0 . DP=29;I16=16,12,0,0,1125,47237,0,0,1618,95282,0,0,553,12773,0,0;QS=3,0;MQSB=0.856268;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,118:3:0 0,27,240:9:0 +X 449 . A <*> 0 . DP=28;I16=15,12,0,0,1091,45981,0,0,1558,91682,0,0,552,12748,0,0;QS=3,0;MQSB=0.84246;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,90:2:0 0,27,245:9:0 +X 450 . G <*> 0 . DP=28;I16=15,12,0,0,1069,44603,0,0,1558,91682,0,0,551,12741,0,0;QS=3,0;MQSB=0.84246;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,91:2:0 0,27,233:9:0 +X 451 . A <*> 0 . DP=28;I16=15,12,0,0,1021,41371,0,0,1558,91682,0,0,550,12752,0,0;QS=3,0;MQSB=0.84246;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,93:2:0 0,27,244:9:0 +X 452 . A <*> 0 . DP=31;I16=18,11,0,0,1079,43353,0,0,1678,98882,0,0,530,12420,0,0;QS=3,0;MQSB=0.884952;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,110:3:0 0,24,225:8:0 +X 453 . A <*> 0 . DP=31;I16=17,11,0,0,1037,41069,0,0,1649,98041,0,0,508,11882,0,0;QS=3,0;MQSB=0.967085;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,111:3:0 0,21,221:7:0 +X 454 . A <*> 0 . DP=31;I16=18,12,0,0,1158,47028,0,0,1738,102482,0,0,554,12904,0,0;QS=3,0;MQSB=0.878946;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,113:3:0 0,30,255:10:0 +X 455 . T <*> 0 . DP=32;I16=17,13,0,0,1148,46574,0,0,1715,100251,0,0,550,12864,0,0;QS=3,0;MQSB=0.973855;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,113:3:0 0,33,255:11:0 +X 456 . G <*> 0 . DP=32;I16=17,13,0,0,1161,47287,0,0,1746,103010,0,0,534,12296,0,0;QS=3,0;MQSB=0.998031;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,116:3:0 0,30,245:10:0 +X 457 . C <*> 0 . DP=33;I16=19,13,0,0,1218,48642,0,0,1835,107451,0,0,563,12967,0,0;QS=3,0;MQSB=0.985204;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,118:3:0 0,33,255:11:0 +X 458 . A <*> 0 . DP=33;I16=19,13,0,0,1226,49034,0,0,1835,107451,0,0,568,12990,0,0;QS=3,0;MQSB=0.985204;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,111:3:0 0,33,255:11:0 +X 459 . T <*> 0 . DP=33;I16=18,13,0,0,1167,46981,0,0,1775,103851,0,0,565,12945,0,0;QS=3,0;MQSB=0.980167;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,92:2:0 0,33,255:11:0 +X 460 . G <*> 0 . DP=32;I16=19,12,0,0,1219,50105,0,0,1775,103851,0,0,575,12929,0,0;QS=3,0;MQSB=0.989977;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,116:3:0 0,30,255:10:0 +X 461 . T <*> 0 . DP=32;I16=19,12,0,0,1213,49819,0,0,1775,103851,0,0,577,12845,0,0;QS=3,0;MQSB=0.989977;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,115:3:0 0,30,255:10:0 +X 462 . G <*> 0 . DP=32;I16=19,12,0,0,1190,48962,0,0,1775,103851,0,0,580,12792,0,0;QS=3,0;MQSB=0.989977;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,119:4:0 0,30,241:10:0 +X 463 . G <*> 0 . DP=32;I16=19,12,0,0,1114,44214,0,0,1775,103851,0,0,584,12770,0,0;QS=3,0;MQSB=0.989977;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,114:4:0 0,30,221:10:0 +X 464 . A <*> 0 . DP=32;I16=18,11,0,0,1100,43908,0,0,1686,99410,0,0,556,12106,0,0;QS=3,0;MQSB=0.99095;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,133:4:0 0,24,213:8:0 +X 465 . C <*> 0 . DP=33;I16=20,11,0,0,1191,48085,0,0,1775,103851,0,0,586,12786,0,0;QS=3,0;MQSB=0.996597;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,140:5:0 0,27,231:9:0 +X 466 . A <*> 0 . DP=34;I16=21,12,0,0,1293,53311,0,0,1895,111051,0,0,597,12897,0,0;QS=3,0;MQSB=0.995633;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,154:5:0 0,30,255:10:0 +X 467 . A <*> 0 . DP=34;I16=21,11,0,0,1256,51450,0,0,1835,107451,0,0,597,12891,0,0;QS=3,0;MQSB=0.998231;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,157:5:0 0,27,248:9:0 +X 468 . A <*> 0 . DP=35;I16=22,12,0,0,1274,51268,0,0,1955,114651,0,0,604,12904,0,0;QS=3,0;MQSB=0.997406;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,154:5:0 0,30,251:10:0 +X 469 . A <*> 0 . DP=35;I16=22,12,0,0,1285,52989,0,0,1955,114651,0,0,608,12940,0,0;QS=3,0;MQSB=0.997406;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,146:5:0 0,30,255:10:0 +X 470 . G <*> 0 . DP=35;I16=22,12,0,0,1281,51055,0,0,1955,114651,0,0,612,13016,0,0;QS=3,0;MQSB=0.997406;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,148:5:0 0,30,238:10:0 +X 471 . T <*> 0 . DP=36;I16=22,11,0,0,1239,49021,0,0,1918,113282,0,0,599,12825,0,0;QS=3,0;MQSB=0.915545;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,150:5:0 0,27,232:9:0 +X 472 . T <*> 0 . DP=35;I16=21,12,0,0,1245,48915,0,0,1926,113810,0,0,595,12559,0,0;QS=3,0;MQSB=0.988858;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,153:5:0 0,27,237:9:0 +X 473 . G <*> 0 . DP=35;I16=21,12,0,0,1307,53473,0,0,1926,113810,0,0,599,12651,0,0;QS=3,0;MQSB=0.988858;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,141:5:0 0,27,249:9:0 +X 474 . G <*> 0 . DP=36;I16=22,12,0,0,1284,51708,0,0,1986,117410,0,0,602,12734,0,0;QS=3,0;MQSB=0.986937;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,131:5:0 0,30,255:10:0 +X 475 . G <*> 0 . DP=36;I16=23,12,0,0,1311,51609,0,0,2015,118251,0,0,631,13485,0,0;QS=3,0;MQSB=0.998642;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,141:5:0 0,33,252:11:0 +X 476 . A <*> 0 . DP=36;I16=23,12,0,0,1312,52078,0,0,2015,118251,0,0,634,13606,0,0;QS=3,0;MQSB=0.998642;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,157:5:0 0,33,255:11:0 +X 477 . T <*> 0 . DP=36;I16=23,12,0,0,1318,52668,0,0,2015,118251,0,0,637,13773,0,0;QS=3,0;MQSB=0.998642;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,148:5:0 0,33,255:11:0 +X 478 . T <*> 0 . DP=38;I16=25,12,0,0,1338,51774,0,0,2135,125451,0,0,637,13833,0,0;QS=3,0;MQSB=0.999868;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,18,154:6:0 0,33,255:11:0 +X 479 . A <*> 0 . DP=38;I16=25,12,0,0,1420,57788,0,0,2135,125451,0,0,639,13935,0,0;QS=3,0;MQSB=0.999868;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,18,163:6:0 0,33,255:11:0 +X 480 . G <*> 0 . DP=37;I16=25,11,0,0,1438,60172,0,0,2075,121851,0,0,641,14029,0,0;QS=3,0;MQSB=0.999853;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,165:6:0 0,33,255:11:0 +X 481 . G <*> 0 . DP=37;I16=25,11,0,0,1392,55824,0,0,2075,121851,0,0,642,14112,0,0;QS=3,0;MQSB=0.999853;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,165:6:0 0,33,255:11:0 +X 482 . A <*> 0 . DP=37;I16=24,11,0,0,1352,55134,0,0,2015,118251,0,0,618,13608,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,143:5:0 0,33,255:11:0 +X 483 . G <*> 0 . DP=37;I16=24,12,0,0,1417,57747,0,0,2075,121851,0,0,642,14240,0,0;QS=3,0;MQSB=0.999437;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,165:6:0 0,33,255:11:0 +X 484 . A <*> 0 . DP=36;I16=24,11,0,0,1340,53992,0,0,2015,118251,0,0,643,14281,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,168:6:0 0,33,255:11:0 +X 485 . G <*> 0 . DP=35;I16=23,12,0,0,1329,51411,0,0,2015,118251,0,0,669,14931,0,0;QS=3,0;MQSB=0.998642;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,160:6:0 0,33,255:11:0 +X 486 . A <*> 0 . DP=34;I16=22,12,0,0,1311,51523,0,0,1955,114651,0,0,671,14989,0,0;QS=3,0;MQSB=0.997406;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,173:6:0 0,33,255:11:0 +X 487 . G <*> 0 . DP=34;I16=22,12,0,0,1306,50760,0,0,1955,114651,0,0,672,15030,0,0;QS=3,0;MQSB=0.997406;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,169:6:0 0,33,255:11:0 +X 488 . A <*> 0 . DP=35;I16=22,12,0,0,1274,48140,0,0,1986,117410,0,0,646,14380,0,0;QS=3,0;MQSB=0.986937;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,177:6:0 0,30,255:10:0 +X 489 . A <*> 0 . DP=35;I16=23,12,0,0,1264,46916,0,0,2015,118251,0,0,671,15015,0,0;QS=3,0;MQSB=0.998642;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,175:6:0 0,33,255:11:0 +X 490 . A <*> 0 . DP=36;I16=24,12,0,0,1332,50280,0,0,2075,121851,0,0,671,15061,0,0;QS=3,0;MQSB=0.999437;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,188:7:0 0,33,255:11:0 +X 491 . T <*> 0 . DP=36;I16=24,12,0,0,1284,46802,0,0,2075,121851,0,0,671,15093,0,0;QS=3,0;MQSB=0.999437;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,178:7:0 0,33,255:11:0 +X 492 . G <*> 0 . DP=35;I16=21,12,0,0,1252,48326,0,0,1926,113810,0,0,621,13859,0,0;QS=3,0;MQSB=0.988858;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,172:6:0 0,30,251:10:0 +X 493 . A <*> 0 . DP=34;I16=22,11,0,0,1273,49481,0,0,1926,113810,0,0,650,14672,0,0;QS=3,0;MQSB=0.981935;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,186:7:0 0,24,240:8:0 +X 494 . A <*> 0 . DP=34;I16=22,12,0,0,1326,52604,0,0,1986,117410,0,0,672,15182,0,0;QS=3,0;MQSB=0.986937;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,196:7:0 0,27,255:9:0 +X 495 . G <*> 0 . DP=34;I16=21,12,0,0,1255,48577,0,0,1926,113810,0,0,647,14611,0,0;QS=3,0;MQSB=0.988858;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,168:6:0 0,27,244:9:0 +X 496 . A <*> 0 . DP=34;I16=22,12,0,0,1250,46926,0,0,1986,117410,0,0,670,15220,0,0;QS=3,0;MQSB=0.986937;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,186:7:0 0,27,249:9:0 +X 497 . C <*> 0 . DP=34;I16=22,12,0,0,1250,47006,0,0,1986,117410,0,0,665,15087,0,0;QS=3,0;MQSB=0.986937;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,164:7:0 0,27,239:9:0 +X 498 . A <*> 0 . DP=34;I16=22,12,0,0,1286,49158,0,0,1986,117410,0,0,661,14987,0,0;QS=3,0;MQSB=0.986937;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,185:7:0 0,27,252:9:0 +X 499 . T <*> 0 . DP=34;I16=23,11,0,0,1224,45284,0,0,1986,117410,0,0,659,14919,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,183:7:0 0,30,255:10:0 +X 500 . A <*> 0 . DP=34;I16=23,11,0,0,1230,45152,0,0,1986,117410,0,0,657,14833,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,179:7:0 0,30,255:10:0 +X 501 . T <*> 0 . DP=33;I16=23,10,0,0,1241,47167,0,0,1926,113810,0,0,656,14778,0,0;QS=3,0;MQSB=0.972757;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,186:7:0 0,27,241:9:0 +X 502 . G <*> 0 . DP=33;I16=23,10,0,0,1215,45829,0,0,1926,113810,0,0,655,14753,0,0;QS=3,0;MQSB=0.972757;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,183:7:0 0,27,235:9:0 +X 503 . T <*> 0 . DP=34;I16=23,11,0,0,1194,43366,0,0,1986,117410,0,0,654,14758,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,177:7:0 0,27,234:9:0 +X 504 . C <*> 0 . DP=34;I16=23,11,0,0,1218,45552,0,0,1986,117410,0,0,651,14643,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,183:7:0 0,27,219:9:0 +X 505 . C <*> 0 . DP=35;I16=23,11,0,0,1207,44321,0,0,1986,117410,0,0,641,14509,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,189:7:0 0,27,221:9:0 +X 506 . A <*> 0 . DP=35;I16=24,11,0,0,1266,46776,0,0,2046,121010,0,0,646,14504,0,0;QS=3,0;MQSB=0.977529;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,188:7:0 0,27,231:9:0 +X 507 . C <*> 0 . DP=35;I16=23,11,0,0,1220,45016,0,0,1986,117410,0,0,635,14401,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,183:7:0 0,27,226:9:0 +X 508 . A <*> 0 . DP=34;I16=24,10,0,0,1204,44542,0,0,1986,117410,0,0,643,14491,0,0;QS=3,0;MQSB=0.970272;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,189:7:0 0,27,220:9:0 +X 509 . C <*> 0 . DP=34;I16=24,10,0,0,1272,48272,0,0,1986,117410,0,0,640,14430,0,0;QS=3,0;MQSB=0.970272;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,186:7:0 0,27,241:9:0 +X 510 . A <*> 0 . DP=34;I16=22,11,0,0,1194,44196,0,0,1926,113810,0,0,613,13773,0,0;QS=3,0;MQSB=0.981935;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,187:7:0 0,24,221:8:0 +X 511 . A <*> 0 . DP=34;I16=23,11,0,0,1222,45562,0,0,1986,117410,0,0,637,14395,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,195:7:0 0,24,233:8:0 +X 512 . A C,<*> 0 . DP=33;I16=22,10,0,1,1121,40793,13,169,1866,110210,60,3600,628,14340,9,81;QS=2.97719,0.022807,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.981935;BQB=1;MQ0F=0 PL:DP:DV 0,39,255,51,255,255:18:1 0,21,183,21,183,183:7:0 0,24,231,24,231,231:8:0 +X 513 . A <*> 0 . DP=32;I16=20,10,0,0,1115,42183,0,0,1746,103010,0,0,598,13624,0,0;QS=3,0;MQSB=0.980594;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,175:6:0 0,24,233:8:0 +X 514 . A T,<*> 0 . DP=32;I16=20,9,0,1,1066,40004,16,256,1686,99410,60,3600,586,13500,11,121;QS=2.97075,0.0292505,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.980594;BQB=1;MQ0F=0 PL:DP:DV 0,31,255,45,255,255:16:1 0,18,171,18,171,171:6:0 0,24,235,24,235,235:8:0 +X 515 . C <*> 0 . DP=32;I16=18,10,0,0,1010,37294,0,0,1626,95810,0,0,561,12915,0,0;QS=3,0;MQSB=0.986018;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,167:6:0 0,24,211:8:0 +X 516 . C <*> 0 . DP=32;I16=21,10,0,0,1100,40570,0,0,1806,106610,0,0,612,13954,0,0;QS=3,0;MQSB=0.977926;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,187:7:0 0,24,215:8:0 +X 517 . T <*> 0 . DP=33;I16=23,10,0,0,1269,49995,0,0,1926,113810,0,0,636,14626,0,0;QS=3,0;MQSB=0.972757;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,201:7:0 0,24,242:8:0 +X 518 . G <*> 0 . DP=34;I16=24,10,0,0,1247,46839,0,0,1986,117410,0,0,636,14696,0,0;QS=3,0;MQSB=0.970272;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,182:7:0 0,24,220:8:0 +X 519 . T <*> 0 . DP=36;I16=25,11,0,0,1283,46693,0,0,2106,124610,0,0,636,14742,0,0;QS=3,0;MQSB=0.975394;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,21,177:7:0 0,24,224:8:0 +X 520 . T <*> 0 . DP=36;I16=24,11,0,0,1238,44894,0,0,2046,121010,0,0,613,14193,0,0;QS=3,0;MQSB=0.977529;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,180:7:0 0,24,223:8:0 +X 521 . C <*> 0 . DP=34;I16=25,9,0,0,1280,49454,0,0,1986,117410,0,0,641,14875,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,191:7:0 0,21,204:7:0 +X 522 . A <*> 0 . DP=32;I16=24,8,0,0,1158,43228,0,0,1897,112969,0,0,646,14960,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,185:7:0 0,15,170:5:0 +X 523 . T G,<*> 0 . DP=32;I16=23,8,1,0,1184,45708,15,225,1837,109369,60,3600,626,14446,25,625;QS=2.9794,0.0206044,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.872525;BQB=1;MQ0F=0 PL:DP:DV 0,44,255,57,255,255:20:1 0,21,191,21,191,191:7:0 0,15,166,15,166,166:5:0 +X 524 . T <*> 0 . DP=32;I16=24,7,0,0,1084,39474,0,0,1837,109369,0,0,629,14483,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,194:7:0 0,12,140:4:0 +X 525 . G <*> 0 . DP=32;I16=24,7,0,0,1181,45669,0,0,1837,109369,0,0,631,14495,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,188:7:0 0,12,129:4:0 +X 526 . C <*> 0 . DP=32;I16=24,7,0,0,1146,43950,0,0,1860,111600,0,0,633,14531,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,185:7:0 0,12,131:4:0 +X 527 . A <*> 0 . DP=33;I16=24,8,0,0,1209,46265,0,0,1897,112969,0,0,636,14634,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,194:7:0 0,18,181:6:0 +X 528 . G <*> 0 . DP=33;I16=24,8,0,0,1256,49824,0,0,1897,112969,0,0,634,14484,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,18,169:6:0 0,18,193:6:0 +X 529 . C <*> 0 . DP=32;I16=24,7,0,0,1148,44362,0,0,1837,109369,0,0,633,14357,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,187:7:0 0,18,184:6:0 +X 530 . T <*> 0 . DP=32;I16=25,7,0,0,1244,49168,0,0,1897,112969,0,0,657,14883,0,0;QS=3,0;MQSB=0.850154;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,196:7:0 0,18,202:6:0 +X 531 . T <*> 0 . DP=32;I16=25,7,0,0,1177,44171,0,0,1897,112969,0,0,654,14714,0,0;QS=3,0;MQSB=0.850154;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,181:7:0 0,18,193:6:0 +X 532 . T <*> 0 . DP=32;I16=24,7,0,0,1153,43543,0,0,1837,109369,0,0,630,14116,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,181:7:0 0,18,192:6:0 +X 533 . C <*> 0 . DP=32;I16=24,7,0,0,1142,43940,0,0,1837,109369,0,0,619,13649,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,178:7:0 0,18,180:6:0 +X 534 . T <*> 0 . DP=31;I16=24,6,0,0,1212,49426,0,0,1777,105769,0,0,615,13479,0,0;QS=3,0;MQSB=0.82403;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,205:7:0 0,18,205:6:0 +X 535 . A <*> 0 . DP=31;I16=24,6,0,0,1080,39870,0,0,1777,105769,0,0,611,13341,0,0;QS=3,0;MQSB=0.82403;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,194:7:0 0,18,189:6:0 +X 536 . C <*> 0 . DP=31;I16=24,7,0,0,1097,40707,0,0,1837,109369,0,0,631,13809,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,184:7:0 0,18,157:6:0 +X 537 . C <*> 0 . DP=31;I16=22,7,0,0,1034,38564,0,0,1717,102169,0,0,587,12861,0,0;QS=3,0;MQSB=0.854582;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,172:7:0 0,18,183:6:0 +X 538 . A <*> 0 . DP=31;I16=24,7,0,0,1138,42478,0,0,1837,109369,0,0,620,13536,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,189:7:0 0,18,181:6:0 +X 539 . T <*> 0 . DP=31;I16=24,7,0,0,1134,42070,0,0,1837,109369,0,0,614,13422,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,178:7:0 0,18,181:6:0 +X 540 . C <*> 0 . DP=31;I16=24,7,0,0,1148,43768,0,0,1837,109369,0,0,608,13340,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,177:7:0 0,18,178:6:0 +X 541 . A <*> 0 . DP=32;I16=24,6,0,0,1083,40483,0,0,1777,105769,0,0,551,11991,0,0;QS=3,0;MQSB=0.82403;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,180:8:0 0,15,150:5:0 +X 542 . C <*> 0 . DP=33;I16=25,6,0,0,1123,41759,0,0,1837,109369,0,0,570,12552,0,0;QS=3,0;MQSB=0.822578;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,172:8:0 0,18,174:6:0 +X 543 . C <*> 0 . DP=34;I16=25,9,0,0,1219,45959,0,0,1986,117410,0,0,601,13245,0,0;QS=3,0;MQSB=0.621145;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,27,194:9:0 0,18,188:6:0 +X 544 . A <*> 0 . DP=33;I16=24,8,0,0,1170,43898,0,0,1866,110210,0,0,570,12506,0,0;QS=3,0;MQSB=0.579578;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,192:8:0 0,18,180:6:0 +X 545 . A <*> 0 . DP=33;I16=25,8,0,0,1174,43602,0,0,1926,113810,0,0,587,12951,0,0;QS=3,0;MQSB=0.576102;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,190:8:0 0,18,184:6:0 +X 546 . A <*> 0 . DP=32;I16=24,8,0,0,1126,41444,0,0,1866,110210,0,0,580,12802,0,0;QS=3,0;MQSB=0.579578;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,166:7:0 0,18,193:6:0 +X 547 . A <*> 0 . DP=32;I16=24,7,0,0,1129,42381,0,0,1806,106610,0,0,547,12009,0,0;QS=3,0;MQSB=0.525788;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,180:7:0 0,18,195:6:0 +X 548 . A <*> 0 . DP=33;I16=23,9,0,0,1153,42673,0,0,1866,110210,0,0,561,12489,0,0;QS=3,0;MQSB=0.628357;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,181:7:0 0,21,211:7:0 +X 549 . T G,<*> 0 . DP=32;I16=22,8,0,1,1101,40987,20,400,1746,103010,60,3600,530,11716,25,625;QS=2.96748,0.0325203,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.632337;BQB=1;MQ0F=0 PL:DP:DV 0,31,255,48,255,255:17:1 0,21,168,21,168,168:7:0 0,21,208,21,208,208:7:0 +X 550 . T <*> 0 . DP=32;I16=22,9,0,0,1052,37298,0,0,1806,106610,0,0,548,12176,0,0;QS=3,0;MQSB=0.632337;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,150:7:0 0,21,220:7:0 +X 551 . G <*> 0 . DP=31;I16=22,9,0,0,1121,41639,0,0,1806,106610,0,0,541,12045,0,0;QS=3,0;MQSB=0.632337;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,172:7:0 0,21,208:7:0 +X 552 . C <*> 0 . DP=30;I16=21,9,0,0,1093,41365,0,0,1746,103010,0,0,535,11947,0,0;QS=3,0;MQSB=0.636601;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,167:7:0 0,21,208:7:0 +X 553 . A <*> 0 . DP=30;I16=20,8,0,0,981,35387,0,0,1626,95810,0,0,485,10831,0,0;QS=3,0;MQSB=0.596163;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,150:6:0 0,21,194:7:0 +X 554 . A <*> 0 . DP=30;I16=19,9,0,0,975,35601,0,0,1626,95810,0,0,488,10906,0,0;QS=3,0;MQSB=0.646113;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,139:5:0 0,24,211:8:0 +X 555 . A <*> 0 . DP=30;I16=20,10,0,0,1024,36526,0,0,1746,103010,0,0,514,11392,0,0;QS=3,0;MQSB=0.679025;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,150:6:0 0,21,211:7:0 +X 556 . C <*> 0 . DP=29;I16=20,9,0,0,1055,39195,0,0,1709,101641,0,0,509,11219,0,0;QS=3,0;MQSB=0.894839;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,158:6:0 0,18,186:6:0 +X 557 . A <*> 0 . DP=27;I16=18,9,0,0,987,36749,0,0,1589,94441,0,0,506,11074,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,157:6:0 0,18,186:6:0 +X 558 . A <*> 0 . DP=27;I16=18,8,0,0,948,35808,0,0,1560,93600,0,0,477,10281,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,143:5:0 0,18,177:6:0 +X 559 . C A,<*> 0 . DP=27;I16=17,8,0,1,908,33726,14,196,1500,90000,29,841,448,9516,25,625;QS=2.92708,0.0729167,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.90038;BQB=1;MQ0F=0 PL:DP:DV 0,42,255,42,255,255:14:0 0,4,116,15,119,123:6:1 0,18,169,18,169,169:6:0 +X 560 . C <*> 0 . DP=28;I16=19,9,0,0,992,36552,0,0,1649,98041,0,0,494,10654,0,0;QS=3,0;MQSB=0.896555;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,160:6:0 0,21,181:7:0 +X 561 . A <*> 0 . DP=28;I16=18,9,0,0,963,35455,0,0,1589,94441,0,0,466,9946,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,158:6:0 0,21,194:7:0 +X 562 . C <*> 0 . DP=28;I16=18,9,0,0,1006,38392,0,0,1589,94441,0,0,463,9893,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,153:6:0 0,21,187:7:0 +X 563 . A <*> 0 . DP=27;I16=17,9,0,0,893,32413,0,0,1529,90841,0,0,460,9820,0,0;QS=3,0;MQSB=0.90038;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,149:5:0 0,21,179:7:0 +X 564 . C <*> 0 . DP=27;I16=18,9,0,0,859,28747,0,0,1589,94441,0,0,482,10402,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,121:5:0 0,21,182:7:0 +X 565 . G <*> 0 . DP=30;I16=17,9,0,0,818,26928,0,0,1560,93600,0,0,454,9764,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,96:4:0 0,21,154:7:0 +X 566 . C <*> 0 . DP=29;I16=15,11,0,0,903,33405,0,0,1529,90841,0,0,424,9084,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,155:5:0 0,18,167:6:0 +X 567 . C <*> 0 . DP=30;I16=15,12,0,0,932,33774,0,0,1589,94441,0,0,462,10178,0,0;QS=3,0;MQSB=0.935229;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,155:5:0 0,21,196:7:0 +X 568 . C <*> 0 . DP=29;I16=15,13,0,0,1057,40817,0,0,1649,98041,0,0,482,10438,0,0;QS=3,0;MQSB=0.942064;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,183:6:0 0,18,189:6:0 +X 569 . T <*> 0 . DP=30;I16=16,12,0,0,1056,41296,0,0,1649,98041,0,0,493,10655,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,190:6:0 0,21,213:7:0 +X 570 . T <*> 0 . DP=30;I16=16,12,0,0,954,34972,0,0,1680,100800,0,0,472,10086,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,157:5:0 0,21,195:7:0 +X 571 . C <*> 0 . DP=31;I16=17,12,0,0,1061,40675,0,0,1740,104400,0,0,472,10158,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,155:5:0 0,21,193:7:0 +X 572 . A <*> 0 . DP=31;I16=18,12,0,0,1102,42642,0,0,1769,105241,0,0,499,10887,0,0;QS=3,0;MQSB=0.929991;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,203:7:0 0,18,175:6:0 +X 573 . A <*> 0 . DP=31;I16=18,12,0,0,1057,38473,0,0,1769,105241,0,0,501,10975,0,0;QS=3,0;MQSB=0.929991;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,199:7:0 0,18,178:6:0 +X 574 . C A,<*> 0 . DP=31;I16=18,11,0,1,1088,41328,15,225,1740,104400,29,841,478,10422,25,625;QS=2.94071,0.0592885,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.929991;BQB=1;MQ0F=0 PL:DP:DV 0,48,255,48,255,255:16:0 0,9,170,21,173,177:8:1 0,18,173,18,173,173:6:0 +X 575 . T <*> 0 . DP=30;I16=16,10,0,0,1024,41260,0,0,1560,93600,0,0,448,9842,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,209:7:0 0,15,163:5:0 +X 576 . G <*> 0 . DP=30;I16=17,12,0,0,1047,40077,0,0,1709,101641,0,0,507,11087,0,0;QS=3,0;MQSB=0.931617;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,208:8:0 0,15,151:5:0 +X 577 . G <*> 0 . DP=30;I16=16,12,0,0,999,37747,0,0,1649,98041,0,0,489,10755,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,204:8:0 0,15,146:5:0 +X 578 . G <*> 0 . DP=29;I16=16,13,0,0,975,34803,0,0,1709,101641,0,0,520,11286,0,0;QS=3,0;MQSB=0.940317;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,198:8:0 0,15,151:5:0 +X 579 . G <*> 0 . DP=30;I16=15,13,0,0,1028,38752,0,0,1649,98041,0,0,484,10514,0,0;QS=3,0;MQSB=0.942064;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,224:8:0 0,12,145:4:0 +X 580 . A C,<*> 0 . DP=30;I16=15,14,1,0,1060,39178,16,256,1709,101641,60,3600,510,11078,17,289;QS=2.97338,0.0266223,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.946202;BQB=1;MQ0F=0 PL:DP:DV 0,34,255,48,255,255:17:1 0,24,221,24,221,221:8:0 0,15,155,15,155,155:5:0 +X 581 . A <*> 0 . DP=31;I16=16,15,0,0,1083,39215,0,0,1829,108841,0,0,530,11384,0,0;QS=3,0;MQSB=0.951229;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,223:8:0 0,15,153:5:0 +X 582 . C <*> 0 . DP=31;I16=15,15,0,0,1080,39870,0,0,1769,105241,0,0,519,11211,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,207:8:0 0,15,151:5:0 +X 583 . T <*> 0 . DP=30;I16=16,14,0,0,1136,43996,0,0,1769,105241,0,0,539,11523,0,0;QS=3,0;MQSB=0.946202;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,238:8:0 0,15,163:5:0 +X 584 . C <*> 0 . DP=31;I16=16,13,0,0,1051,39351,0,0,1709,101641,0,0,499,10619,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,207:7:0 0,15,157:5:0 +X 585 . A <*> 0 . DP=31;I16=17,14,0,0,1096,39866,0,0,1798,106082,0,0,549,11751,0,0;QS=3,0;MQSB=0.998229;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,211:8:0 0,15,157:5:0 +X 586 . T <*> 0 . DP=31;I16=16,14,0,0,1081,39839,0,0,1738,102482,0,0,546,11796,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,212:8:0 0,15,156:5:0 +X 587 . C <*> 0 . DP=31;I16=17,13,0,0,1070,39402,0,0,1769,105241,0,0,532,11350,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,201:7:0 0,15,155:5:0 +X 588 . A <*> 0 . DP=31;I16=17,14,0,0,1126,41642,0,0,1798,106082,0,0,562,12140,0,0;QS=3,0;MQSB=0.998229;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,222:8:0 0,15,164:5:0 +X 589 . A <*> 0 . DP=31;I16=17,14,0,0,1157,43973,0,0,1798,106082,0,0,568,12340,0,0;QS=3,0;MQSB=0.998229;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,236:8:0 0,15,165:5:0 +X 590 . C <*> 0 . DP=32;I16=16,14,0,0,1094,41302,0,0,1769,105241,0,0,549,11951,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,192:6:0 0,18,175:6:0 +X 591 . A <*> 0 . DP=31;I16=16,15,0,0,1165,44163,0,0,1798,106082,0,0,579,12695,0,0;QS=3,0;MQSB=0.999805;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,209:7:0 0,18,188:6:0 +X 592 . A <*> 0 . DP=31;I16=15,15,0,0,1114,42144,0,0,1738,102482,0,0,571,12651,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,215:7:0 0,18,182:6:0 +X 593 . C <*> 0 . DP=31;I16=15,14,0,0,1065,39889,0,0,1709,101641,0,0,550,12132,0,0;QS=3,0;MQSB=0.954405;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,191:6:0 0,18,174:6:0 +X 594 . A <*> 0 . DP=33;I16=16,16,0,0,1163,42917,0,0,1858,109682,0,0,572,12672,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,205:7:0 0,24,212:8:0 +X 595 . A <*> 0 . DP=33;I16=17,16,0,0,1130,39996,0,0,1918,113282,0,0,589,12905,0,0;QS=3,0;MQSB=0.999838;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,198:7:0 0,24,213:8:0 +X 596 . A <*> 0 . DP=33;I16=16,16,0,0,1059,37039,0,0,1858,109682,0,0,590,12952,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,169:7:0 0,24,230:8:0 +X 597 . C <*> 0 . DP=33;I16=17,16,0,0,1196,44890,0,0,1918,113282,0,0,592,12990,0,0;QS=3,0;MQSB=0.999838;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,204:7:0 0,24,220:8:0 +X 598 . T <*> 0 . DP=33;I16=16,16,0,0,1214,47104,0,0,1858,109682,0,0,593,13013,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,217:7:0 0,24,239:8:0 +X 599 . T <*> 0 . DP=33;I16=16,17,0,0,1183,43669,0,0,1918,113282,0,0,599,13095,0,0;QS=3,0;MQSB=0.999838;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,197:7:0 0,27,247:9:0 +X 600 . G <*> 0 . DP=32;I16=15,17,0,0,1174,44066,0,0,1858,109682,0,0,601,13145,0,0;QS=3,0;MQSB=0.999287;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,194:7:0 0,24,232:8:0 +X 601 . T <*> 0 . DP=32;I16=15,17,0,0,1114,39954,0,0,1858,109682,0,0,603,13227,0,0;QS=3,0;MQSB=0.999287;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,188:7:0 0,24,235:8:0 +X 602 . G <*> 0 . DP=32;I16=15,15,0,0,1090,40326,0,0,1769,105241,0,0,555,12091,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,185:6:0 0,24,229:8:0 +X 603 . G <*> 0 . DP=31;I16=15,16,0,0,1052,37460,0,0,1798,106082,0,0,607,13437,0,0;QS=3,0;MQSB=0.999805;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,186:7:0 0,24,219:8:0 +X 604 . T <*> 0 . DP=31;I16=14,16,0,0,1009,35893,0,0,1769,105241,0,0,564,12540,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,195:8:0 0,21,212:7:0 +X 605 . T <*> 0 . DP=31;I16=12,15,0,0,1001,37741,0,0,1589,94441,0,0,514,11258,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,200:7:0 0,21,214:7:0 +X 606 . T <*> 0 . DP=31;I16=13,16,0,0,992,35202,0,0,1709,101641,0,0,587,13125,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,189:7:0 0,24,217:8:0 +X 607 . A <*> 0 . DP=31;I16=14,16,0,0,1027,36129,0,0,1738,102482,0,0,607,13577,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,176:7:0 0,24,222:8:0 +X 608 . C <*> 0 . DP=32;I16=15,15,0,0,983,33775,0,0,1769,105241,0,0,564,12564,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,178:7:0 0,27,214:9:0 +X 609 . C <*> 0 . DP=32;I16=14,17,0,0,1074,38220,0,0,1798,106082,0,0,606,13678,0,0;QS=3,0;MQSB=0.998229;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,190:7:0 0,27,238:9:0 +X 610 . C <*> 0 . DP=32;I16=15,16,0,0,1158,44218,0,0,1829,108841,0,0,594,13444,0,0;QS=3,0;MQSB=0.951229;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,211:8:0 0,27,246:9:0 +X 611 . A <*> 0 . DP=32;I16=15,16,0,0,1080,39204,0,0,1798,106082,0,0,590,13260,0,0;QS=3,0;MQSB=0.999805;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,220:9:0 0,27,246:9:0 +X 612 . C <*> 0 . DP=33;I16=16,17,0,0,1175,43305,0,0,1918,113282,0,0,617,13993,0,0;QS=3,0;MQSB=0.999838;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,214:9:0 0,27,250:9:0 +X 613 . A <*> 0 . DP=34;I16=16,17,0,0,1131,40011,0,0,1949,116041,0,0,604,13874,0,0;QS=3,0;MQSB=0.954207;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,223:9:0 0,27,239:9:0 +X 614 . C <*> 0 . DP=34;I16=16,17,0,0,1183,43743,0,0,1949,116041,0,0,608,14022,0,0;QS=3,0;MQSB=0.954207;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,223:9:0 0,27,245:9:0 +X 615 . A <*> 0 . DP=34;I16=16,18,0,0,1199,43809,0,0,1978,116882,0,0,626,14394,0,0;QS=3,0;MQSB=0.999405;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,30,240:10:0 0,27,254:9:0 +X 616 . A <*> 0 . DP=34;I16=16,17,0,0,1190,44024,0,0,1949,116041,0,0,615,14351,0,0;QS=3,0;MQSB=0.954207;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,247:9:0 0,27,255:9:0 +X 617 . T <*> 0 . DP=33;I16=15,18,0,0,1170,43066,0,0,1918,113282,0,0,630,14624,0,0;QS=3,0;MQSB=0.998531;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,30,241:10:0 0,27,255:9:0 +X 618 . G <*> 0 . DP=34;I16=15,19,0,0,1166,41452,0,0,1978,116882,0,0,632,14706,0,0;QS=3,0;MQSB=0.997597;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,30,248:10:0 0,27,240:9:0 +X 619 . G <*> 0 . DP=32;I16=14,18,0,0,1153,42591,0,0,1858,109682,0,0,638,14816,0,0;QS=3,0;MQSB=0.997118;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,30,254:10:0 0,27,247:9:0 +X 620 . A <*> 0 . DP=32;I16=14,17,0,0,1083,39757,0,0,1798,106082,0,0,616,14176,0,0;QS=3,0;MQSB=0.998229;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,30,248:10:0 0,27,255:9:0 +X 621 . A <*> 0 . DP=32;I16=13,18,0,0,1170,45248,0,0,1798,106082,0,0,627,14519,0,0;QS=3,0;MQSB=0.995005;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,255:9:0 0,27,255:9:0 +X 622 . G <*> 0 . DP=32;I16=12,18,0,0,1060,39160,0,0,1769,105241,0,0,604,13888,0,0;QS=3,0;MQSB=0.968257;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,236:9:0 0,27,249:9:0 +X 623 . A T,<*> 0 . DP=32;I16=10,18,1,0,1010,37414,15,225,1649,98041,60,3600,563,12953,25,625;QS=2.96144,0.0385604,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.969907;BQB=1;MQ0F=0 PL:DP:DV 0,20,241,33,244,246:12:1 0,24,213,24,213,213:8:0 0,27,255,27,255,255:9:0 +X 624 . C <*> 0 . DP=32;I16=13,17,0,0,1034,37292,0,0,1738,102482,0,0,607,13887,0,0;QS=3,0;MQSB=0.996503;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,220:9:0 0,27,242:9:0 +X 625 . C <*> 0 . DP=32;I16=13,18,0,0,1108,41138,0,0,1798,106082,0,0,632,14470,0,0;QS=3,0;MQSB=0.995005;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,234:9:0 0,27,249:9:0 +X 626 . A <*> 0 . DP=32;I16=13,17,0,0,1090,40718,0,0,1738,102482,0,0,607,13827,0,0;QS=3,0;MQSB=0.996503;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,237:9:0 0,27,247:9:0 +X 627 . C <*> 0 . DP=32;I16=12,18,0,0,1146,44452,0,0,1769,105241,0,0,607,13833,0,0;QS=3,0;MQSB=0.968257;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,244:9:0 0,27,255:9:0 +X 628 . T <*> 0 . DP=32;I16=11,19,0,0,1124,43114,0,0,1769,105241,0,0,608,13862,0,0;QS=3,0;MQSB=0.972375;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,249:9:0 0,24,249:8:0 +X 629 . T <*> 0 . DP=32;I16=12,19,0,0,1114,41138,0,0,1798,106082,0,0,634,14490,0,0;QS=3,0;MQSB=0.989977;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,247:9:0 0,24,226:8:0 +X 630 . A <*> 0 . DP=31;I16=11,18,0,0,1101,42885,0,0,1740,104400,0,0,610,13844,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,242:8:0 0,24,235:8:0 +X 631 . G <*> 0 . DP=31;I16=12,18,0,0,1083,40525,0,0,1769,105241,0,0,636,14474,0,0;QS=3,0;MQSB=0.929991;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,233:8:0 0,24,223:8:0 +X 632 . C <*> 0 . DP=31;I16=11,18,0,0,1105,42665,0,0,1740,104400,0,0,612,13880,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,233:8:0 0,24,224:8:0 +X 633 . A <*> 0 . DP=31;I16=12,18,0,0,1056,38190,0,0,1769,105241,0,0,638,14562,0,0;QS=3,0;MQSB=0.929991;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,218:8:0 0,24,214:8:0 +X 634 . A <*> 0 . DP=31;I16=12,18,0,0,1110,42208,0,0,1769,105241,0,0,638,14594,0,0;QS=3,0;MQSB=0.929991;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,238:8:0 0,24,229:8:0 +X 635 . C <*> 0 . DP=31;I16=11,18,0,0,1031,37871,0,0,1740,104400,0,0,613,14025,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,220:8:0 0,24,229:8:0 +X 636 . A <*> 0 . DP=31;I16=11,18,0,0,1115,43327,0,0,1740,104400,0,0,611,14005,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,228:8:0 0,24,243:8:0 +X 637 . A <*> 0 . DP=31;I16=12,18,0,0,1152,44602,0,0,1769,105241,0,0,634,14634,0,0;QS=3,0;MQSB=0.929991;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,238:8:0 0,24,242:8:0 +X 638 . A <*> 0 . DP=31;I16=12,18,0,0,1118,42406,0,0,1769,105241,0,0,631,14611,0,0;QS=3,0;MQSB=0.929991;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,235:8:0 0,24,238:8:0 +X 639 . A <*> 0 . DP=30;I16=11,18,0,0,1037,38233,0,0,1709,101641,0,0,602,13934,0,0;QS=3,0;MQSB=0.921439;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,230:8:0 0,24,227:8:0 +X 640 . A <*> 0 . DP=31;I16=11,19,0,0,1154,45368,0,0,1769,105241,0,0,596,13804,0,0;QS=3,0;MQSB=0.91982;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,242:8:0 0,24,240:8:0 +X 641 . G <*> 0 . DP=31;I16=11,19,0,0,1018,36496,0,0,1769,105241,0,0,590,13650,0,0;QS=3,0;MQSB=0.91982;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,214:8:0 0,24,218:8:0 +X 642 . G <*> 0 . DP=30;I16=11,19,0,0,1057,38459,0,0,1769,105241,0,0,610,14148,0,0;QS=3,0;MQSB=0.91982;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,187:7:0 0,24,221:8:0 +X 643 . A <*> 0 . DP=29;I16=11,17,0,0,969,35477,0,0,1649,98041,0,0,585,13605,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,199:7:0 0,24,237:8:0 +X 644 . C A,<*> 0 . DP=29;I16=9,18,1,0,898,30864,17,289,1620,97200,60,3600,549,12567,25,625;QS=2.95685,0.0431472,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,22,236,36,239,243:13:1 0,21,195,21,195,195:7:0 0,24,204,24,204,204:8:0 +X 645 . C <*> 0 . DP=30;I16=10,19,0,0,1067,40337,0,0,1709,101641,0,0,584,13274,0,0;QS=3,0;MQSB=0.909373;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,198:7:0 0,24,226:8:0 +X 646 . A T,<*> 0 . DP=31;I16=9,20,1,0,1044,38174,14,196,1740,104400,60,3600,553,12499,25,625;QS=2.97113,0.028866,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,27,255,39,255,255:14:1 0,21,197,21,197,197:7:0 0,27,229,27,229,229:9:0 +X 647 . A <*> 0 . DP=33;I16=10,21,0,0,1041,35883,0,0,1829,108841,0,0,573,12999,0,0;QS=3,0;MQSB=0.906252;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,189:7:0 0,30,213:10:0 +X 648 . A <*> 0 . DP=33;I16=11,22,0,0,1030,34122,0,0,1949,116041,0,0,594,13478,0,0;QS=3,0;MQSB=0.915545;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,188:7:0 0,30,194:10:0 +X 649 . C <*> 0 . DP=32;I16=10,21,0,0,1099,39879,0,0,1860,111600,0,0,566,12738,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,188:7:0 0,27,217:9:0 +X 650 . T <*> 0 . DP=31;I16=11,18,0,0,1006,37114,0,0,1709,101641,0,0,549,12407,0,0;QS=3,0;MQSB=0.921439;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,187:6:0 0,24,226:8:0 +X 651 . C <*> 0 . DP=32;I16=11,20,0,0,1117,41181,0,0,1829,108841,0,0,581,13107,0,0;QS=3,0;MQSB=0.918304;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,186:6:0 0,27,229:9:0 +X 652 . C <*> 0 . DP=32;I16=9,21,0,0,1126,43084,0,0,1769,105241,0,0,557,12423,0,0;QS=3,0;MQSB=0.893237;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,196:6:0 0,24,213:8:0 +X 653 . T <*> 0 . DP=33;I16=9,23,0,0,1141,42631,0,0,1889,112441,0,0,556,12382,0,0;QS=3,0;MQSB=0.890331;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,198:6:0 0,24,225:8:0 +X 654 . G <*> 0 . DP=33;I16=10,23,0,0,1171,43025,0,0,1949,116041,0,0,578,12798,0,0;QS=3,0;MQSB=0.903508;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,191:6:0 0,24,223:8:0 +X 655 . G <*> 0 . DP=32;I16=10,22,0,0,1118,40202,0,0,1889,112441,0,0,575,12573,0,0;QS=3,0;MQSB=0.904837;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,181:6:0 0,24,213:8:0 +X 656 . T <*> 0 . DP=32;I16=10,22,0,0,1090,38566,0,0,1889,112441,0,0,571,12333,0,0;QS=3,0;MQSB=0.904837;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,185:6:0 0,24,213:8:0 +X 657 . A <*> 0 . DP=32;I16=10,21,0,0,1100,40006,0,0,1829,108841,0,0,557,12029,0,0;QS=3,0;MQSB=0.906252;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,183:6:0 0,24,191:8:0 +X 658 . C <*> 0 . DP=32;I16=10,21,0,0,1115,41039,0,0,1829,108841,0,0,542,11520,0,0;QS=3,0;MQSB=0.906252;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,168:5:0 0,24,211:8:0 +X 659 . A <*> 0 . DP=32;I16=10,21,0,0,1141,42897,0,0,1829,108841,0,0,547,11685,0,0;QS=3,0;MQSB=0.906252;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,191:6:0 0,24,216:8:0 +X 660 . T <*> 0 . DP=33;I16=10,22,0,0,1139,41887,0,0,1889,112441,0,0,553,11659,0,0;QS=3,0;MQSB=0.904837;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,186:6:0 0,24,214:8:0 +X 661 . G <*> 0 . DP=32;I16=9,22,0,0,1107,41531,0,0,1829,108841,0,0,549,11549,0,0;QS=3,0;MQSB=0.891738;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,191:6:0 0,21,188:7:0 +X 662 . C <*> 0 . DP=32;I16=8,22,0,0,1087,40811,0,0,1800,108000,0,0,523,10991,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,192:6:0 0,21,187:7:0 +X 663 . A <*> 0 . DP=32;I16=9,22,0,0,1036,36816,0,0,1829,108841,0,0,540,11388,0,0;QS=3,0;MQSB=0.891738;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,192:6:0 0,21,186:7:0 +X 664 . A <*> 0 . DP=32;I16=9,23,0,0,1125,40759,0,0,1889,112441,0,0,552,11628,0,0;QS=3,0;MQSB=0.890331;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,188:6:0 0,21,184:7:0 +X 665 . C <*> 0 . DP=30;I16=9,21,0,0,1075,39697,0,0,1769,105241,0,0,550,11650,0,0;QS=3,0;MQSB=0.893237;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,186:6:0 0,21,184:7:0 +X 666 . T <*> 0 . DP=29;I16=9,20,0,0,1096,41946,0,0,1709,101641,0,0,547,11607,0,0;QS=3,0;MQSB=0.894839;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,171:5:0 0,21,194:7:0 +X 667 . G <*> 0 . DP=31;I16=11,19,0,0,1037,37627,0,0,1769,105241,0,0,524,11198,0,0;QS=3,0;MQSB=0.91982;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,189:6:0 0,21,188:7:0 +X 668 . A <*> 0 . DP=31;I16=11,20,0,0,1102,39980,0,0,1829,108841,0,0,543,11625,0,0;QS=3,0;MQSB=0.918304;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,190:6:0 0,21,187:7:0 +X 669 . C <*> 0 . DP=30;I16=10,19,0,0,1051,38869,0,0,1740,104400,0,0,528,11464,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,182:6:0 0,21,189:7:0 +X 670 . A <*> 0 . DP=30;I16=11,19,0,0,1121,43423,0,0,1769,105241,0,0,540,11642,0,0;QS=3,0;MQSB=0.91982;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,194:6:0 0,21,205:7:0 +X 671 . G <*> 0 . DP=30;I16=11,19,0,0,1101,41035,0,0,1769,105241,0,0,537,11637,0,0;QS=3,0;MQSB=0.91982;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,181:6:0 0,21,191:7:0 +X 672 . A <*> 0 . DP=30;I16=10,19,0,0,1031,37795,0,0,1740,104400,0,0,521,11479,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,185:6:0 0,21,185:7:0 +X 673 . T <*> 0 . DP=29;I16=8,19,0,0,954,34984,0,0,1589,94441,0,0,497,10885,0,0;QS=3,0;MQSB=0.880529;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,126:4:0 0,21,192:7:0 +X 674 . G <*> 0 . DP=29;I16=10,18,0,0,974,35736,0,0,1649,98041,0,0,497,10827,0,0;QS=3,0;MQSB=0.911099;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,146:5:0 0,21,185:7:0 +X 675 . A <*> 0 . DP=28;I16=9,19,0,0,996,36338,0,0,1649,98041,0,0,517,11389,0,0;QS=3,0;MQSB=0.896555;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,124:4:0 0,21,189:7:0 +X 676 . A <*> 0 . DP=29;I16=8,19,0,0,988,36578,0,0,1589,94441,0,0,462,10106,0,0;QS=3,0;MQSB=0.880529;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,128:4:0 0,21,186:7:0 +X 677 . T <*> 0 . DP=29;I16=9,20,0,0,1006,36126,0,0,1709,101641,0,0,507,11303,0,0;QS=3,0;MQSB=0.894839;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,120:4:0 0,21,192:7:0 +X 678 . C <*> 0 . DP=29;I16=9,20,0,0,1020,36984,0,0,1709,101641,0,0,502,11280,0,0;QS=3,0;MQSB=0.894839;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,117:4:0 0,21,191:7:0 +X 679 . T <*> 0 . DP=27;I16=6,19,0,0,902,33612,0,0,1469,87241,0,0,460,10414,0,0;QS=3,0;MQSB=0.833024;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,96:3:0 0,21,195:7:0 +X 680 . C <*> 0 . DP=26;I16=7,18,0,0,879,32295,0,0,1469,87241,0,0,468,10482,0,0;QS=3,0;MQSB=0.862128;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,98:3:0 0,21,181:7:0 +X 681 . A <*> 0 . DP=27;I16=7,17,0,0,844,30190,0,0,1409,83641,0,0,465,10425,0,0;QS=3,0;MQSB=0.864405;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,106:3:0 0,21,174:7:0 +X 682 . A <*> 0 . DP=27;I16=7,20,0,0,919,32179,0,0,1589,94441,0,0,500,11096,0,0;QS=3,0;MQSB=0.858077;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,145:5:0 0,21,176:7:0 +X 683 . A <*> 0 . DP=29;I16=8,21,0,0,949,32735,0,0,1709,101641,0,0,499,11103,0,0;QS=3,0;MQSB=0.876998;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,172:6:0 0,21,167:7:0 +X 684 . C <*> 0 . DP=29;I16=6,21,0,0,802,24468,0,0,1589,94441,0,0,473,10459,0,0;QS=3,0;MQSB=0.829029;MQ0F=0 PL:DP:DV 0,45,251:15:0 0,15,118:5:0 0,21,145:7:0 +X 685 . G <*> 0 . DP=28;I16=6,21,0,0,908,32092,0,0,1620,97200,0,0,498,11090,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,130:5:0 0,21,175:7:0 +X 686 . C <*> 0 . DP=28;I16=7,21,0,0,977,35493,0,0,1680,100800,0,0,500,11080,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,170:6:0 0,21,180:7:0 +X 687 . A <*> 0 . DP=28;I16=6,20,0,0,900,31952,0,0,1560,93600,0,0,475,10469,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,175:6:0 0,21,174:7:0 +X 688 . T <*> 0 . DP=27;I16=6,21,0,0,937,33971,0,0,1620,97200,0,0,501,11135,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,153:6:0 0,21,187:7:0 +X 689 . T A,<*> 0 . DP=27;I16=5,20,1,0,829,28967,13,169,1500,90000,60,3600,463,10359,25,625;QS=2.97105,0.0289532,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,28,231,39,234,234:14:1 0,15,116,15,116,116:5:0 0,21,185,21,185,185:7:0 +X 690 . C <*> 0 . DP=27;I16=6,20,0,0,935,34553,0,0,1560,93600,0,0,486,10974,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,146:5:0 0,21,165:7:0 +X 691 . C <*> 0 . DP=26;I16=5,18,0,0,842,31906,0,0,1380,82800,0,0,446,10166,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,129:4:0 0,18,161:6:0 +X 692 . T <*> 0 . DP=26;I16=6,19,0,0,886,32434,0,0,1500,90000,0,0,486,11082,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,146:5:0 0,18,164:6:0 +X 693 . C <*> 0 . DP=27;I16=6,20,0,0,891,31839,0,0,1560,93600,0,0,483,11007,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,141:5:0 0,21,172:7:0 +X 694 . C <*> 0 . DP=27;I16=6,21,0,0,808,25004,0,0,1620,97200,0,0,498,11248,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,242:14:0 0,18,136:6:0 0,21,146:7:0 +X 695 . G <*> 0 . DP=25;I16=4,20,0,0,807,28037,0,0,1440,86400,0,0,476,10692,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,246:13:0 0,18,145:6:0 0,15,124:5:0 +X 696 . T <*> 0 . DP=25;I16=5,20,0,0,896,32870,0,0,1500,90000,0,0,499,11129,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,150:6:0 0,15,141:5:0 +X 697 . G <*> 0 . DP=26;I16=5,19,0,0,852,30594,0,0,1409,83641,0,0,450,9858,0,0;QS=3,0;MQSB=0.796124;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,142:5:0 0,15,120:5:0 +X 698 . T <*> 0 . DP=27;I16=6,20,0,0,917,33201,0,0,1529,90841,0,0,502,11114,0,0;QS=3,0;MQSB=0.83095;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,154:6:0 0,15,131:5:0 +X 699 . G <*> 0 . DP=28;I16=5,21,0,0,923,34103,0,0,1529,90841,0,0,498,10884,0,0;QS=3,0;MQSB=0.79189;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,163:6:0 0,15,132:5:0 +X 700 . A <*> 0 . DP=28;I16=6,22,0,0,989,35833,0,0,1618,95282,0,0,530,11626,0,0;QS=3,0;MQSB=0.904554;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,169:7:0 0,18,148:6:0 +X 701 . A <*> 0 . DP=29;I16=5,23,0,0,992,35956,0,0,1618,95282,0,0,517,11459,0,0;QS=3,0;MQSB=0.864394;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,186:7:0 0,18,144:6:0 +X 702 . A <*> 0 . DP=29;I16=5,23,0,0,1103,44105,0,0,1618,95282,0,0,520,11508,0,0;QS=3,0;MQSB=0.864394;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,204:7:0 0,18,159:6:0 +X 703 . G <*> 0 . DP=29;I16=5,23,0,0,1014,37508,0,0,1618,95282,0,0,522,11534,0,0;QS=3,0;MQSB=0.864394;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,172:7:0 0,18,144:6:0 +X 704 . A T,<*> 0 . DP=29;I16=4,23,1,0,954,34200,16,256,1558,91682,60,3600,499,10963,13,169;QS=2.97064,0.0293578,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.864394;BQB=1;MQ0F=0 PL:DP:DV 0,31,255,45,255,255:16:1 0,18,154,18,154,154:6:0 0,18,139,18,139,139:6:0 +X 705 . A <*> 0 . DP=29;I16=6,22,0,0,1042,39930,0,0,1618,95282,0,0,513,11189,0,0;QS=3,0;MQSB=0.904554;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,189:7:0 0,18,157:6:0 +X 706 . G <*> 0 . DP=30;I16=6,23,0,0,1029,37763,0,0,1678,98882,0,0,513,11225,0,0;QS=3,0;MQSB=0.900586;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,170:7:0 0,18,131:6:0 +X 707 . C <*> 0 . DP=30;I16=5,22,0,0,944,34494,0,0,1558,91682,0,0,464,10040,0,0;QS=3,0;MQSB=0.868709;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,131:5:0 0,18,134:6:0 +X 708 . C <*> 0 . DP=30;I16=6,24,0,0,898,27574,0,0,1738,102482,0,0,540,12010,0,0;QS=3,0;MQSB=0.896846;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,153:8:0 0,18,110:6:0 +X 709 . G <*> 0 . DP=29;I16=5,22,0,0,968,36130,0,0,1558,91682,0,0,507,11343,0,0;QS=3,0;MQSB=0.868709;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,178:8:0 0,15,132:5:0 +X 710 . G <*> 0 . DP=29;I16=5,23,0,0,961,34825,0,0,1618,95282,0,0,533,12029,0,0;QS=3,0;MQSB=0.864394;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,174:8:0 0,15,122:5:0 +X 711 . A <*> 0 . DP=29;I16=6,23,0,0,996,35700,0,0,1647,96123,0,0,565,12723,0,0;QS=3,0;MQSB=0.957107;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,171:7:0 0,18,142:6:0 +X 712 . C <*> 0 . DP=29;I16=6,23,0,0,1069,40863,0,0,1647,96123,0,0,565,12767,0,0;QS=3,0;MQSB=0.957107;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,156:7:0 0,18,146:6:0 +X 713 . T <*> 0 . DP=29;I16=6,23,0,0,1072,40426,0,0,1647,96123,0,0,565,12835,0,0;QS=3,0;MQSB=0.957107;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,187:7:0 0,18,149:6:0 +X 714 . C <*> 0 . DP=28;I16=6,21,0,0,988,37236,0,0,1558,91682,0,0,541,12301,0,0;QS=3,0;MQSB=0.90877;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,153:6:0 0,15,125:5:0 +X 715 . A <*> 0 . DP=28;I16=6,20,0,0,884,31414,0,0,1498,88082,0,0,522,12004,0,0;QS=3,0;MQSB=0.913254;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,138:6:0 0,15,120:5:0 +X 716 . C <*> 0 . DP=29;I16=4,23,0,0,998,37756,0,0,1527,88923,0,0,547,12501,0,0;QS=3,0;MQSB=0.877203;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,141:5:0 0,18,145:6:0 +X 717 . A <*> 0 . DP=31;I16=8,23,0,0,1136,42928,0,0,1767,103323,0,0,574,13254,0,0;QS=3,0;MQSB=0.987595;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,212:8:0 0,18,153:6:0 +X 718 . G <*> 0 . DP=29;I16=7,22,0,0,1066,40006,0,0,1647,96123,0,0,579,13407,0,0;QS=3,0;MQSB=0.979435;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,223:8:0 0,18,139:6:0 +X 719 . G <*> 0 . DP=29;I16=7,19,0,0,952,35868,0,0,1529,90841,0,0,510,11756,0,0;QS=3,0;MQSB=0.860025;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,204:8:0 0,12,120:4:0 +X 720 . G <*> 0 . DP=28;I16=6,20,0,0,986,37838,0,0,1467,85323,0,0,552,12940,0,0;QS=3,0;MQSB=0.970805;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,216:8:0 0,18,147:6:0 +X 721 . C <*> 0 . DP=28;I16=6,21,0,0,989,36901,0,0,1527,88923,0,0,567,13183,0,0;QS=3,0;MQSB=0.966147;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,197:8:0 0,18,147:6:0 +X 722 . A <*> 0 . DP=28;I16=6,21,0,0,949,33837,0,0,1527,88923,0,0,569,13225,0,0;QS=3,0;MQSB=0.966147;MQ0F=0 PL:DP:DV 0,39,244:13:0 0,24,205:8:0 0,18,143:6:0 +X 723 . A <*> 0 . DP=28;I16=6,19,0,0,925,34825,0,0,1438,84482,0,0,530,12366,0,0;QS=3,0;MQSB=0.918029;MQ0F=0 PL:DP:DV 0,36,253:12:0 0,24,206:8:0 0,15,135:5:0 +X 724 . C <*> 0 . DP=28;I16=5,22,0,0,967,35983,0,0,1527,88923,0,0,566,13028,0,0;QS=3,0;MQSB=0.932273;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,161:7:0 0,18,140:6:0 +X 725 . A <*> 0 . DP=28;I16=6,21,0,0,911,31971,0,0,1527,88923,0,0,565,12987,0,0;QS=3,0;MQSB=0.966147;MQ0F=0 PL:DP:DV 0,42,246:14:0 0,21,168:7:0 0,18,137:6:0 +X 726 . C <*> 0 . DP=28;I16=6,21,0,0,947,34531,0,0,1527,88923,0,0,563,12919,0,0;QS=3,0;MQSB=0.966147;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,166:7:0 0,18,136:6:0 +X 727 . A C,<*> 0 . DP=28;I16=6,20,0,1,904,32194,17,289,1498,88082,29,841,535,12199,25,625;QS=2.90811,0.0918919,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.966147;BQB=1;MQ0F=0 PL:DP:DV 0,42,247,42,247,247:14:0 0,21,191,21,191,191:7:0 0,1,109,15,112,119:6:1 +X 728 . C <*> 0 . DP=29;I16=6,22,0,0,1018,37990,0,0,1587,92523,0,0,557,12701,0,0;QS=3,0;MQSB=0.961573;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,208:8:0 0,18,142:6:0 +X 729 . T <*> 0 . DP=29;I16=7,22,0,0,1063,39315,0,0,1647,96123,0,0,581,13227,0,0;QS=3,0;MQSB=0.979435;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,244:9:0 0,18,142:6:0 +X 730 . A <*> 0 . DP=29;I16=7,21,0,0,993,35883,0,0,1618,95282,0,0,555,12529,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,219:9:0 0,15,135:5:0 +X 731 . T <*> 0 . DP=29;I16=7,22,0,0,1024,37312,0,0,1647,96123,0,0,578,13058,0,0;QS=3,0;MQSB=0.979435;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,210:9:0 0,18,148:6:0 +X 732 . C <*> 0 . DP=29;I16=7,21,0,0,1006,37058,0,0,1618,95282,0,0,550,12314,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,219:9:0 0,15,129:5:0 +X 733 . T <*> 0 . DP=29;I16=7,21,0,0,985,35497,0,0,1618,95282,0,0,547,12221,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,222:9:0 0,15,134:5:0 +X 734 . G <*> 0 . DP=29;I16=7,21,0,0,997,36453,0,0,1587,92523,0,0,544,12154,0,0;QS=3,0;MQSB=0.982906;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,204:8:0 0,18,139:6:0 +X 735 . A <*> 0 . DP=30;I16=7,21,0,0,963,33993,0,0,1618,95282,0,0,515,11437,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,190:8:0 0,18,148:6:0 +X 736 . C <*> 0 . DP=30;I16=8,20,0,0,1042,39326,0,0,1618,95282,0,0,512,11320,0,0;QS=3,0;MQSB=0.954515;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,218:8:0 0,18,152:6:0 +X 737 . T <*> 0 . DP=30;I16=8,22,0,0,1071,39825,0,0,1707,99723,0,0,560,12480,0,0;QS=3,0;MQSB=0.990151;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,243:9:0 0,21,149:7:0 +X 738 . G <*> 0 . DP=30;I16=8,21,0,0,1016,36816,0,0,1678,98882,0,0,533,11793,0,0;QS=3,0;MQSB=0.950946;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,210:9:0 0,18,141:6:0 +X 739 . T <*> 0 . DP=30;I16=7,22,0,0,1020,37326,0,0,1647,96123,0,0,534,11900,0,0;QS=3,0;MQSB=0.979435;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,202:8:0 0,21,155:7:0 +X 740 . T <*> 0 . DP=29;I16=7,21,0,0,1011,37465,0,0,1587,92523,0,0,532,11848,0,0;QS=3,0;MQSB=0.982906;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,232:8:0 0,21,155:7:0 +X 741 . T <*> 0 . DP=29;I16=7,21,0,0,984,36052,0,0,1587,92523,0,0,528,11722,0,0;QS=3,0;MQSB=0.982906;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,224:8:0 0,21,151:7:0 +X 742 . C <*> 0 . DP=30;I16=8,21,0,0,1046,39056,0,0,1678,98882,0,0,525,11671,0,0;QS=3,0;MQSB=0.950946;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,243:9:0 0,18,136:6:0 +X 743 . A <*> 0 . DP=30;I16=8,21,0,0,1026,37156,0,0,1678,98882,0,0,520,11500,0,0;QS=3,0;MQSB=0.950946;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,239:9:0 0,18,131:6:0 +X 744 . T <*> 0 . DP=30;I16=8,22,0,0,1100,41010,0,0,1707,99723,0,0,540,11984,0,0;QS=3,0;MQSB=0.990151;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,247:9:0 0,21,154:7:0 +X 745 . G <*> 0 . DP=31;I16=9,22,0,0,1078,38890,0,0,1767,103323,0,0,535,11873,0,0;QS=3,0;MQSB=0.996219;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,227:9:0 0,24,178:8:0 +X 746 . G <*> 0 . DP=31;I16=9,21,0,0,1001,35191,0,0,1707,99723,0,0,531,11793,0,0;QS=3,0;MQSB=0.997698;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,201:9:0 0,24,178:8:0 +X 747 . G <*> 0 . DP=30;I16=9,20,0,0,1017,36831,0,0,1647,96123,0,0,509,11343,0,0;QS=3,0;MQSB=0.99889;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,201:8:0 0,21,174:7:0 +X 748 . A <*> 0 . DP=30;I16=10,20,0,0,1046,37438,0,0,1707,99723,0,0,529,11721,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,242:9:0 0,18,159:6:0 +X 749 . A <*> 0 . DP=31;I16=10,21,0,0,1077,38303,0,0,1767,103323,0,0,530,11728,0,0;QS=3,0;MQSB=0.999777;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,27,240:9:0 0,18,164:6:0 +X 750 . A <*> 0 . DP=32;I16=10,20,0,0,1129,43093,0,0,1738,102482,0,0,500,11252,0,0;QS=3,0;MQSB=0.976097;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,232:8:0 0,15,161:5:0 +X 751 . G <*> 0 . DP=31;I16=11,20,0,0,1065,37955,0,0,1767,103323,0,0,535,11787,0,0;QS=3,0;MQSB=0.999148;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,27,206:9:0 0,18,150:6:0 +X 752 . T <*> 0 . DP=31;I16=11,20,0,0,1034,35786,0,0,1767,103323,0,0,537,11793,0,0;QS=3,0;MQSB=0.999148;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,27,223:9:0 0,18,143:6:0 +X 753 . C <*> 0 . DP=31;I16=12,19,0,0,1073,38779,0,0,1767,103323,0,0,540,11834,0,0;QS=3,0;MQSB=0.994873;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,30,227:10:0 0,18,158:6:0 +X 754 . T <*> 0 . DP=31;I16=12,19,0,0,1135,42527,0,0,1767,103323,0,0,542,11808,0,0;QS=3,0;MQSB=0.994873;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,30,255:10:0 0,18,172:6:0 +X 755 . G <*> 0 . DP=31;I16=12,19,0,0,1157,43695,0,0,1767,103323,0,0,544,11814,0,0;QS=3,0;MQSB=0.994873;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,30,255:10:0 0,18,162:6:0 +X 756 . G <*> 0 . DP=30;I16=12,17,0,0,1002,35566,0,0,1647,96123,0,0,539,11753,0,0;QS=3,0;MQSB=0.988062;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,30,242:10:0 0,18,157:6:0 +X 757 . A <*> 0 . DP=30;I16=12,17,0,0,1035,37723,0,0,1678,98882,0,0,523,11197,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,30,248:10:0 0,15,152:5:0 +X 758 . A <*> 0 . DP=30;I16=12,18,0,0,1015,35685,0,0,1707,99723,0,0,549,11825,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,30,247:10:0 0,18,156:6:0 +X 759 . A <*> 0 . DP=30;I16=12,16,0,0,998,36498,0,0,1618,95282,0,0,526,11472,0,0;QS=3,0;MQSB=0.995699;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,242:9:0 0,15,151:5:0 +X 760 . C <*> 0 . DP=31;I16=12,18,0,0,916,29466,0,0,1707,99723,0,0,547,11741,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,30,217:10:0 0,18,128:6:0 +X 761 . G <*> 0 . DP=30;I16=11,16,0,0,932,32884,0,0,1589,94441,0,0,512,11028,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,220:9:0 0,15,153:5:0 +X 762 . G <*> 0 . DP=29;I16=11,18,0,0,1012,36984,0,0,1647,96123,0,0,541,11629,0,0;QS=3,0;MQSB=0.995968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,220:9:0 0,21,173:7:0 +X 763 . C A,<*> 0 . DP=29;I16=11,16,0,1,948,35124,15,225,1558,91682,29,841,527,11473,2,4;QS=2.93697,0.0630252,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.993109;BQB=1;MQ0F=0 PL:DP:DV 0,39,255,39,255,255:13:0 0,24,193,24,193,193:8:0 0,6,158,18,161,165:7:1 +X 764 . A <*> 0 . DP=31;I16=12,18,0,0,1051,37737,0,0,1738,102482,0,0,516,11020,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,30,250:10:0 0,18,163:6:0 +X 765 . A <*> 0 . DP=32;I16=12,18,0,0,1071,39369,0,0,1738,102482,0,0,525,11379,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,30,254:10:0 0,18,169:6:0 +X 766 . C <*> 0 . DP=31;I16=13,18,0,0,1065,38285,0,0,1798,106082,0,0,547,11797,0,0;QS=3,0;MQSB=0.995005;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,33,235:11:0 0,18,164:6:0 +X 767 . A <*> 0 . DP=30;I16=12,18,0,0,996,34692,0,0,1738,102482,0,0,552,11926,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,244:11:0 0,18,148:6:0 +X 768 . C <*> 0 . DP=30;I16=12,18,0,0,1095,40739,0,0,1738,102482,0,0,556,12038,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,255:11:0 0,18,173:6:0 +X 769 . C <*> 0 . DP=30;I16=12,18,0,0,1110,42272,0,0,1738,102482,0,0,559,12133,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,255:11:0 0,18,173:6:0 +X 770 . A <*> 0 . DP=30;I16=12,18,0,0,1098,40852,0,0,1738,102482,0,0,562,12262,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,255:11:0 0,18,171:6:0 +X 771 . T <*> 0 . DP=30;I16=12,18,0,0,1111,41771,0,0,1738,102482,0,0,563,12325,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,255:11:0 0,18,177:6:0 +X 772 . T <*> 0 . DP=30;I16=12,18,0,0,1107,41429,0,0,1738,102482,0,0,563,12373,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,255:11:0 0,18,176:6:0 +X 773 . G <*> 0 . DP=30;I16=12,18,0,0,1123,42761,0,0,1738,102482,0,0,562,12406,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,255:11:0 0,18,175:6:0 +X 774 . A <*> 0 . DP=30;I16=12,18,0,0,1151,44801,0,0,1738,102482,0,0,560,12422,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,255:11:0 0,18,179:6:0 +X 775 . G <*> 0 . DP=30;I16=12,18,0,0,1136,43766,0,0,1738,102482,0,0,557,12419,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,255:11:0 0,18,177:6:0 +X 776 . A <*> 0 . DP=29;I16=12,17,0,0,1053,38865,0,0,1678,98882,0,0,553,12345,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,30,255:10:0 0,18,169:6:0 +X 777 . C <*> 0 . DP=28;I16=12,16,0,0,1019,37631,0,0,1618,95282,0,0,550,12298,0,0;QS=3,0;MQSB=0.995699;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,229:9:0 0,18,165:6:0 +X 778 . A <*> 0 . DP=28;I16=12,16,0,0,1079,42041,0,0,1618,95282,0,0,547,12277,0,0;QS=3,0;MQSB=0.995699;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,241:9:0 0,18,181:6:0 +X 779 . G <*> 0 . DP=28;I16=12,16,0,0,1025,38825,0,0,1618,95282,0,0,543,12231,0,0;QS=3,0;MQSB=0.995699;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,231:9:0 0,18,170:6:0 +X 780 . A <*> 0 . DP=28;I16=12,16,0,0,1005,36773,0,0,1618,95282,0,0,538,12160,0,0;QS=3,0;MQSB=0.995699;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,242:9:0 0,18,166:6:0 +X 781 . A <*> 0 . DP=28;I16=12,15,0,0,965,35857,0,0,1589,94441,0,0,519,11889,0,0;QS=3,0;MQSB=0.935229;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,222:8:0 0,15,159:5:0 +X 782 . A <*> 0 . DP=28;I16=12,16,0,0,1003,37315,0,0,1618,95282,0,0,530,12044,0,0;QS=3,0;MQSB=0.995699;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,229:8:0 0,18,171:6:0 +X 783 . A <*> 0 . DP=28;I16=12,16,0,0,989,36477,0,0,1618,95282,0,0,527,12001,0,0;QS=3,0;MQSB=0.995699;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,230:8:0 0,21,178:7:0 +X 784 . C <*> 0 . DP=26;I16=11,15,0,0,967,36387,0,0,1498,88082,0,0,527,11983,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,207:7:0 0,21,178:7:0 +X 785 . A <*> 0 . DP=26;I16=11,15,0,0,989,38499,0,0,1498,88082,0,0,527,11989,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,213:7:0 0,21,187:7:0 +X 786 . G <*> 0 . DP=26;I16=11,14,0,0,938,35698,0,0,1438,84482,0,0,501,11343,0,0;QS=3,0;MQSB=0.996634;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,211:7:0 0,21,180:7:0 +X 787 . G <*> 0 . DP=26;I16=11,15,0,0,914,33428,0,0,1498,88082,0,0,525,11969,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,189:7:0 0,21,175:7:0 +X 788 . T <*> 0 . DP=26;I16=11,15,0,0,913,33357,0,0,1498,88082,0,0,524,11992,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,180:7:0 0,21,188:7:0 +X 789 . G <*> 0 . DP=26;I16=11,15,0,0,963,36645,0,0,1498,88082,0,0,523,12037,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,193:7:0 0,21,183:7:0 +X 790 . A <*> 0 . DP=26;I16=11,15,0,0,999,39113,0,0,1498,88082,0,0,520,12002,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,198:7:0 0,21,201:7:0 +X 791 . G <*> 0 . DP=26;I16=11,15,0,0,934,34208,0,0,1498,88082,0,0,516,11934,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,180:7:0 0,21,172:7:0 +X 792 . T <*> 0 . DP=26;I16=11,15,0,0,895,32009,0,0,1498,88082,0,0,511,11833,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,184:7:0 0,21,172:7:0 +X 793 . G <*> 0 . DP=27;I16=11,15,0,0,965,36389,0,0,1498,88082,0,0,504,11652,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,193:7:0 0,21,170:7:0 +X 794 . G <*> 0 . DP=26;I16=11,15,0,0,888,31804,0,0,1498,88082,0,0,508,11592,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,198:8:0 0,18,161:6:0 +X 795 . T <*> 0 . DP=26;I16=9,15,0,0,859,31399,0,0,1409,83641,0,0,472,10908,0,0;QS=3,0;MQSB=0.96464;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,211:7:0 0,18,160:6:0 +X 796 . T <*> 0 . DP=27;I16=11,16,0,0,907,31641,0,0,1558,91682,0,0,499,11375,0,0;QS=3,0;MQSB=0.992419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,221:9:0 0,15,150:5:0 +X 797 . G <*> 0 . DP=26;I16=11,15,0,0,882,31700,0,0,1529,90841,0,0,498,11298,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,215:9:0 0,12,135:4:0 +X 798 . C <*> 0 . DP=26;I16=9,15,0,0,806,28552,0,0,1440,86400,0,0,466,10582,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,207:8:0 0,12,126:4:0 +X 799 . C <*> 0 . DP=26;I16=10,15,0,0,947,36407,0,0,1500,90000,0,0,491,11185,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,234:9:0 0,12,137:4:0 +X 800 . T <*> 0 . DP=26;I16=11,15,0,0,993,38475,0,0,1529,90841,0,0,495,11199,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,255:9:0 0,12,139:4:0 +X 801 . G <*> 0 . DP=25;I16=11,14,0,0,938,35854,0,0,1469,87241,0,0,495,11209,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,240:9:0 0,12,145:4:0 +X 802 . G <*> 0 . DP=25;I16=11,14,0,0,892,32802,0,0,1469,87241,0,0,495,11239,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,229:9:0 0,12,137:4:0 +X 803 . G <*> 0 . DP=25;I16=11,14,0,0,906,33502,0,0,1469,87241,0,0,495,11289,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,237:9:0 0,12,136:4:0 +X 804 . G <*> 0 . DP=25;I16=11,12,0,0,868,33326,0,0,1349,80041,0,0,466,10846,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,223:8:0 0,12,138:4:0 +X 805 . C <*> 0 . DP=24;I16=9,14,0,0,810,29684,0,0,1380,82800,0,0,482,11208,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,220:8:0 0,12,128:4:0 +X 806 . C <*> 0 . DP=25;I16=9,14,0,0,814,29856,0,0,1380,82800,0,0,483,11293,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,214:8:0 0,12,122:4:0 +X 807 . A <*> 0 . DP=25;I16=10,15,0,0,939,35997,0,0,1500,90000,0,0,503,11525,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,242:9:0 0,12,146:4:0 +X 808 . G <*> 0 . DP=25;I16=10,15,0,0,918,34720,0,0,1500,90000,0,0,505,11591,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,238:9:0 0,12,136:4:0 +X 809 . G <*> 0 . DP=25;I16=10,15,0,0,926,34932,0,0,1500,90000,0,0,506,11626,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,226:9:0 0,12,136:4:0 +X 810 . G C,<*> 0 . DP=25;I16=10,13,0,1,824,30436,14,196,1380,82800,60,3600,480,11288,14,196;QS=2.96552,0.0344828,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,21,255,33,255,255:12:1 0,24,216,24,216,216:8:0 0,12,132,12,132,132:4:0 +X 811 . A <*> 0 . DP=25;I16=9,14,0,0,808,29404,0,0,1380,82800,0,0,484,11294,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,204:7:0 0,12,139:4:0 +X 812 . A <*> 0 . DP=25;I16=10,15,0,0,831,29515,0,0,1500,90000,0,0,500,11392,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,216:9:0 0,12,139:4:0 +X 813 . C <*> 0 . DP=25;I16=10,15,0,0,915,34093,0,0,1500,90000,0,0,497,11307,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,239:9:0 0,12,138:4:0 +X 814 . T <*> 0 . DP=25;I16=10,15,0,0,987,39343,0,0,1500,90000,0,0,494,11244,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,255:9:0 0,12,148:4:0 +X 815 . T <*> 0 . DP=25;I16=10,15,0,0,894,32670,0,0,1500,90000,0,0,491,11203,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,235:9:0 0,12,143:4:0 +X 816 . T <*> 0 . DP=25;I16=10,15,0,0,898,32990,0,0,1500,90000,0,0,488,11184,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,239:9:0 0,12,136:4:0 +X 817 . C <*> 0 . DP=24;I16=10,14,0,0,898,34256,0,0,1440,86400,0,0,485,11137,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,235:9:0 0,12,124:4:0 +X 818 . T <*> 0 . DP=23;I16=9,14,0,0,883,34371,0,0,1380,82800,0,0,484,11110,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,225:8:0 0,12,143:4:0 +X 819 . G <*> 0 . DP=23;I16=9,13,0,0,832,31932,0,0,1320,79200,0,0,461,10573,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,217:8:0 0,12,142:4:0 +X 820 . G <*> 0 . DP=24;I16=10,14,0,0,844,30848,0,0,1440,86400,0,0,484,11114,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,230:9:0 0,12,135:4:0 +X 821 . G <*> 0 . DP=24;I16=10,14,0,0,852,31572,0,0,1440,86400,0,0,484,11098,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,234:9:0 0,12,142:4:0 +X 822 . G <*> 0 . DP=25;I16=10,15,0,0,879,31785,0,0,1500,90000,0,0,481,10955,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,220:9:0 0,12,127:4:0 +X 823 . T <*> 0 . DP=25;I16=10,15,0,0,844,29686,0,0,1500,90000,0,0,478,10786,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,217:9:0 0,12,127:4:0 +X 824 . C <*> 0 . DP=25;I16=9,14,0,0,824,30252,0,0,1380,82800,0,0,427,9477,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,215:9:0 0,9,98:3:0 +X 825 . A <*> 0 . DP=25;I16=10,15,0,0,881,31665,0,0,1500,90000,0,0,467,10277,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,234:9:0 0,12,116:4:0 +X 826 . T <*> 0 . DP=25;I16=10,15,0,0,826,28364,0,0,1500,90000,0,0,461,10039,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,250:12:0 0,27,232:9:0 0,12,117:4:0 +X 827 . A <*> 0 . DP=25;I16=10,15,0,0,851,29477,0,0,1500,90000,0,0,455,9829,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,227:9:0 0,12,123:4:0 +X 828 . T C,<*> 0 . DP=25;I16=2,4,8,11,199,6917,656,23340,360,21600,1140,68400,116,2716,333,6931;QS=0.597777,2.40222,0;VDB=0.842082;SGB=-4.20907;RPB=0.950652;MQB=1;MQSB=1;BQB=0.929717;MQ0F=0 PL:DP:DV 211,0,35,217,65,255:12:10 116,0,91,128,106,213:9:5 120,12,0,120,12,120:4:4 +X 829 . T <*> 0 . DP=24;I16=10,13,0,0,863,32931,0,0,1380,82800,0,0,418,8818,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,242:8:0 0,12,132:4:0 +X 830 . C <*> 0 . DP=24;I16=10,14,0,0,910,34966,0,0,1440,86400,0,0,437,9267,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,220:8:0 0,12,134:4:0 +X 831 . T <*> 0 . DP=24;I16=10,14,0,0,906,34886,0,0,1440,86400,0,0,431,9119,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,243:8:0 0,12,133:4:0 +X 832 . C <*> 0 . DP=24;I16=10,14,0,0,888,33634,0,0,1440,86400,0,0,425,8999,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,220:8:0 0,12,123:4:0 +X 833 . T <*> 0 . DP=25;I16=10,14,0,0,820,29920,0,0,1440,86400,0,0,418,8856,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,224:8:0 0,12,113:4:0 +X 834 . G A,<*> 0 . DP=25;I16=2,3,7,10,164,5898,590,21124,300,18000,1020,61200,104,2296,305,6441;QS=0.520056,2.47994,0;VDB=0.788006;SGB=-4.01214;RPB=0.999233;MQB=1;MQSB=1;BQB=0.821668;MQ0F=0 PL:DP:DV 185,0,46,191,73,246:11:9 128,0,59,137,74,193:8:5 89,9,0,89,9,89:3:3 +X 835 . T <*> 0 . DP=26;I16=9,15,0,0,767,26675,0,0,1440,86400,0,0,406,8652,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,240:12:0 0,24,213:8:0 0,12,98:4:0 +X 836 . G <*> 0 . DP=23;I16=8,15,0,0,833,30561,0,0,1380,82800,0,0,403,8541,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,243:11:0 0,24,214:8:0 0,12,130:4:0 +X 837 . T <*> 0 . DP=23;I16=8,15,0,0,843,31499,0,0,1380,82800,0,0,400,8456,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,241:11:0 0,24,221:8:0 0,12,143:4:0 +X 838 . T <*> 0 . DP=23;I16=8,15,0,0,870,33172,0,0,1380,82800,0,0,397,8397,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,252:11:0 0,24,224:8:0 0,12,134:4:0 +X 839 . G <*> 0 . DP=24;I16=8,15,0,0,862,32774,0,0,1380,82800,0,0,393,8315,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,249:11:0 0,24,212:8:0 0,12,142:4:0 +X 840 . A <*> 0 . DP=25;I16=9,15,0,0,876,32682,0,0,1440,86400,0,0,375,7731,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,243:11:0 0,21,196:7:0 0,18,180:6:0 +X 841 . T <*> 0 . DP=25;I16=9,16,0,0,861,30879,0,0,1500,90000,0,0,396,8260,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,213:11:0 0,24,226:8:0 0,18,185:6:0 +X 842 . T <*> 0 . DP=24;I16=9,15,0,0,872,31990,0,0,1440,86400,0,0,393,8199,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,227:10:0 0,24,231:8:0 0,18,175:6:0 +X 843 . C <*> 0 . DP=24;I16=9,15,0,0,844,30604,0,0,1440,86400,0,0,390,8172,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,228:10:0 0,24,229:8:0 0,18,160:6:0 +X 844 . T <*> 0 . DP=24;I16=9,15,0,0,900,34094,0,0,1440,86400,0,0,386,8128,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,227:10:0 0,24,238:8:0 0,18,189:6:0 +X 845 . G <*> 0 . DP=25;I16=10,15,0,0,916,33866,0,0,1500,90000,0,0,382,8116,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,239:10:0 0,24,225:8:0 0,21,196:7:0 +X 846 . G <*> 0 . DP=24;I16=9,14,0,0,802,28414,0,0,1380,82800,0,0,354,7460,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,223:9:0 0,24,208:8:0 0,18,164:6:0 +X 847 . T <*> 0 . DP=24;I16=8,15,0,0,809,29007,0,0,1380,82800,0,0,377,8083,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,210:9:0 0,24,219:8:0 0,18,149:6:0 +X 848 . G <*> 0 . DP=23;I16=8,15,0,0,829,30351,0,0,1380,82800,0,0,384,8138,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,199:8:0 0,27,243:9:0 0,18,167:6:0 +X 849 . G <*> 0 . DP=22;I16=8,12,0,0,684,23844,0,0,1200,72000,0,0,349,7517,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,160:6:0 0,27,233:9:0 0,15,140:5:0 +X 850 . T <*> 0 . DP=21;I16=6,14,0,0,706,25508,0,0,1200,72000,0,0,360,7568,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,153:6:0 0,24,226:8:0 0,18,147:6:0 +X 851 . G <*> 0 . DP=21;I16=7,14,0,0,707,24667,0,0,1260,75600,0,0,386,8254,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,140:6:0 0,27,233:9:0 0,18,156:6:0 +X 852 . G <*> 0 . DP=21;I16=7,13,0,0,687,24223,0,0,1200,72000,0,0,368,7976,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,147:6:0 0,27,222:9:0 0,15,146:5:0 +X 853 . A <*> 0 . DP=21;I16=7,14,0,0,721,25603,0,0,1260,75600,0,0,388,8442,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,146:6:0 0,27,223:9:0 0,18,166:6:0 +X 854 . A <*> 0 . DP=21;I16=7,14,0,0,725,25843,0,0,1260,75600,0,0,389,8517,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,179:7:0 0,24,209:8:0 0,18,168:6:0 +X 855 . A <*> 0 . DP=21;I16=7,14,0,0,683,23803,0,0,1260,75600,0,0,391,8611,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,171:7:0 0,24,204:8:0 0,18,152:6:0 +X 856 . C <*> 0 . DP=21;I16=7,14,0,0,763,28293,0,0,1260,75600,0,0,392,8676,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,192:7:0 0,24,222:8:0 0,18,172:6:0 +X 857 . A <*> 0 . DP=22;I16=8,14,0,0,786,28480,0,0,1320,79200,0,0,393,8763,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,182:7:0 0,24,220:8:0 0,21,194:7:0 +X 858 . A <*> 0 . DP=22;I16=8,14,0,0,816,31358,0,0,1320,79200,0,0,395,8873,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,192:7:0 0,24,236:8:0 0,21,198:7:0 +X 859 . G <*> 0 . DP=22;I16=8,14,0,0,824,31356,0,0,1320,79200,0,0,395,8907,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,202:7:0 0,24,223:8:0 0,21,203:7:0 +X 860 . A <*> 0 . DP=22;I16=8,13,0,0,743,26985,0,0,1260,75600,0,0,369,8291,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,184:7:0 0,21,202:7:0 0,21,190:7:0 +X 861 . C <*> 0 . DP=22;I16=8,14,0,0,770,28376,0,0,1320,79200,0,0,393,8899,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,206:8:0 0,24,216:8:0 0,18,161:6:0 +X 862 . T <*> 0 . DP=22;I16=8,14,0,0,762,27500,0,0,1320,79200,0,0,393,8905,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,188:8:0 0,24,213:8:0 0,18,177:6:0 +X 863 . G <*> 0 . DP=23;I16=9,14,0,0,836,30660,0,0,1380,82800,0,0,393,8935,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,24,221:8:0 0,18,180:6:0 +X 864 . T <*> 0 . DP=22;I16=9,13,0,0,795,29085,0,0,1320,79200,0,0,395,8989,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,215:8:0 0,24,221:8:0 0,18,180:6:0 +X 865 . C <*> 0 . DP=22;I16=8,14,0,0,785,28475,0,0,1320,79200,0,0,397,9015,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,21,193:7:0 0,18,177:6:0 +X 866 . C <*> 0 . DP=21;I16=7,13,0,0,694,24890,0,0,1200,72000,0,0,395,8985,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,220:8:0 0,18,149:6:0 0,18,177:6:0 +X 867 . C <*> 0 . DP=21;I16=7,14,0,0,761,28443,0,0,1260,75600,0,0,403,9023,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,223:9:0 0,18,182:6:0 0,18,187:6:0 +X 868 . A <*> 0 . DP=21;I16=7,14,0,0,799,31183,0,0,1260,75600,0,0,406,9054,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,18,189:6:0 0,18,202:6:0 +X 869 . G <*> 0 . DP=21;I16=7,14,0,0,795,30733,0,0,1260,75600,0,0,409,9103,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,236:9:0 0,18,190:6:0 0,18,187:6:0 +X 870 . C <*> 0 . DP=21;I16=7,13,0,0,758,29080,0,0,1200,72000,0,0,403,9089,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,226:8:0 0,18,183:6:0 0,18,187:6:0 +X 871 . C <*> 0 . DP=21;I16=7,14,0,0,769,29383,0,0,1260,75600,0,0,413,9155,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,232:9:0 0,18,176:6:0 0,18,192:6:0 +X 872 . T <*> 0 . DP=21;I16=7,14,0,0,785,29879,0,0,1260,75600,0,0,413,9109,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,18,187:6:0 0,18,188:6:0 +X 873 . G <*> 0 . DP=21;I16=7,14,0,0,768,28506,0,0,1260,75600,0,0,413,9083,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,18,172:6:0 0,18,182:6:0 +X 874 . G <*> 0 . DP=21;I16=7,12,0,0,700,26434,0,0,1140,68400,0,0,374,8234,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,227:8:0 0,15,143:5:0 0,18,189:6:0 +X 875 . G <*> 0 . DP=21;I16=7,14,0,0,717,25659,0,0,1260,75600,0,0,411,8995,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,18,163:6:0 0,18,159:6:0 +X 876 . T <*> 0 . DP=21;I16=7,14,0,0,719,25261,0,0,1260,75600,0,0,410,8984,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,222:9:0 0,18,156:6:0 0,18,173:6:0 +X 877 . G <*> 0 . DP=21;I16=7,14,0,0,747,27419,0,0,1260,75600,0,0,409,8995,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,235:9:0 0,18,162:6:0 0,18,176:6:0 +X 878 . A <*> 0 . DP=21;I16=7,13,0,0,738,27650,0,0,1200,72000,0,0,391,8739,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,216:8:0 0,18,172:6:0 0,18,191:6:0 +X 879 . T <*> 0 . DP=21;I16=7,13,0,0,731,26927,0,0,1200,72000,0,0,389,8759,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,214:8:0 0,18,175:6:0 0,18,184:6:0 +X 880 . A <*> 0 . DP=21;I16=7,14,0,0,737,26481,0,0,1260,75600,0,0,405,9109,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,18,165:6:0 0,18,172:6:0 +X 881 . C <*> 0 . DP=20;I16=7,13,0,0,742,27898,0,0,1200,72000,0,0,404,9154,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,231:8:0 0,18,164:6:0 0,18,183:6:0 +X 882 . A <*> 0 . DP=20;I16=7,13,0,0,776,30564,0,0,1200,72000,0,0,403,9217,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,225:8:0 0,18,188:6:0 0,18,200:6:0 +X 883 . G <*> 0 . DP=20;I16=7,13,0,0,702,25898,0,0,1200,72000,0,0,401,9247,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,214:8:0 0,18,175:6:0 0,18,176:6:0 +X 884 . C <*> 0 . DP=19;I16=7,12,0,0,629,21449,0,0,1140,68400,0,0,400,9292,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,201:8:0 0,18,155:6:0 0,15,144:5:0 +X 885 . G <*> 0 . DP=18;I16=7,11,0,0,605,20851,0,0,1080,64800,0,0,400,9350,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,215:8:0 0,15,140:5:0 0,15,130:5:0 +X 886 . A <*> 0 . DP=18;I16=7,11,0,0,681,26145,0,0,1080,64800,0,0,400,9420,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,222:8:0 0,15,164:5:0 0,15,163:5:0 +X 887 . G <*> 0 . DP=18;I16=7,11,0,0,631,22891,0,0,1080,64800,0,0,399,9451,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,222:8:0 0,15,138:5:0 0,15,149:5:0 +X 888 . A <*> 0 . DP=18;I16=7,10,0,0,593,21563,0,0,1020,61200,0,0,373,8867,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,216:8:0 0,15,132:5:0 0,12,127:4:0 +X 889 . C <*> 0 . DP=18;I16=7,11,0,0,624,22732,0,0,1080,64800,0,0,396,9492,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,213:8:0 0,15,134:5:0 0,15,160:5:0 +X 890 . C <*> 0 . DP=19;I16=7,11,0,0,616,22426,0,0,1080,64800,0,0,368,8826,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,215:8:0 0,15,138:5:0 0,15,152:5:0 +X 891 . C <*> 0 . DP=19;I16=7,11,0,0,661,24891,0,0,1080,64800,0,0,365,8745,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,227:8:0 0,15,141:5:0 0,15,165:5:0 +X 892 . C <*> 0 . DP=19;I16=7,12,0,0,691,25761,0,0,1140,68400,0,0,387,9299,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,230:9:0 0,15,146:5:0 0,15,167:5:0 +X 893 . A <*> 0 . DP=19;I16=7,12,0,0,673,24521,0,0,1140,68400,0,0,384,9238,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,221:9:0 0,15,142:5:0 0,15,166:5:0 +X 894 . T <*> 0 . DP=19;I16=7,12,0,0,670,24268,0,0,1140,68400,0,0,380,9138,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,225:9:0 0,15,134:5:0 0,15,165:5:0 +X 895 . C <*> 0 . DP=20;I16=8,12,0,0,712,26186,0,0,1200,72000,0,0,376,9050,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,15,149:5:0 0,15,162:5:0 +X 896 . T <*> 0 . DP=19;I16=8,10,0,0,684,26696,0,0,1080,64800,0,0,348,8300,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,12,141:4:0 0,15,180:5:0 +X 897 . C <*> 0 . DP=18;I16=8,10,0,0,693,27001,0,0,1080,64800,0,0,370,8764,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,12,131:4:0 0,15,166:5:0 +X 898 . T <*> 0 . DP=18;I16=8,10,0,0,674,25656,0,0,1080,64800,0,0,367,8617,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,243:9:0 0,12,125:4:0 0,15,172:5:0 +X 899 . A <*> 0 . DP=18;I16=9,8,0,0,597,21451,0,0,1020,61200,0,0,340,7858,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,9,99:3:0 0,15,145:5:0 +X 900 . C <*> 0 . DP=18;I16=9,9,0,0,658,24550,0,0,1080,64800,0,0,364,8362,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,98:3:0 0,15,166:5:0 +X 901 . C <*> 0 . DP=18;I16=9,9,0,0,680,26004,0,0,1080,64800,0,0,363,8255,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,99:3:0 0,15,169:5:0 +X 902 . A <*> 0 . DP=18;I16=9,9,0,0,681,26253,0,0,1080,64800,0,0,362,8162,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,9,115:3:0 0,15,174:5:0 +X 903 . A <*> 0 . DP=18;I16=9,8,0,0,645,24625,0,0,1020,61200,0,0,336,7458,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,250:9:0 0,9,101:3:0 0,15,171:5:0 +X 904 . A <*> 0 . DP=18;I16=9,9,0,0,640,23412,0,0,1080,64800,0,0,359,7969,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,9,85:3:0 0,15,174:5:0 +X 905 . A <*> 0 . DP=18;I16=9,9,0,0,675,25673,0,0,1080,64800,0,0,357,7871,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,103:3:0 0,15,172:5:0 +X 906 . A <*> 0 . DP=18;I16=9,9,0,0,669,25193,0,0,1080,64800,0,0,355,7789,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,102:3:0 0,15,166:5:0 +X 907 . A <*> 0 . DP=18;I16=9,9,0,0,661,24541,0,0,1080,64800,0,0,353,7723,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,94:3:0 0,15,165:5:0 +X 908 . T <*> 0 . DP=18;I16=9,9,0,0,673,25579,0,0,1080,64800,0,0,351,7673,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,83:3:0 0,15,168:5:0 +X 909 . T <*> 0 . DP=18;I16=9,9,0,0,653,23847,0,0,1080,64800,0,0,348,7590,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,95:3:0 0,15,161:5:0 +X 910 . A <*> 0 . DP=18;I16=9,9,0,0,652,23790,0,0,1080,64800,0,0,344,7476,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,9,104:3:0 0,15,162:5:0 +X 911 . A <*> 0 . DP=18;I16=9,9,0,0,688,26440,0,0,1080,64800,0,0,340,7382,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,109:3:0 0,15,168:5:0 +X 912 . A <*> 0 . DP=18;I16=9,9,0,0,691,26705,0,0,1080,64800,0,0,336,7308,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,115:3:0 0,15,173:5:0 +X 913 . A <*> 0 . DP=19;I16=9,10,0,0,692,25762,0,0,1140,68400,0,0,332,7254,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,109:3:0 0,15,171:5:0 +X 914 . A <*> 0 . DP=19;I16=9,10,0,0,712,26966,0,0,1140,68400,0,0,329,7221,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,109:3:0 0,15,164:5:0 +X 915 . T <*> 0 . DP=18;I16=9,9,0,0,638,23228,0,0,1080,64800,0,0,326,7160,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,9,99:3:0 0,15,163:5:0 +X 916 . T <*> 0 . DP=19;I16=9,8,0,0,626,23136,0,0,1020,61200,0,0,296,6396,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,9,103:3:0 0,15,164:5:0 +X 917 . A <*> 0 . DP=19;I16=9,10,0,0,726,27962,0,0,1117,66169,0,0,318,6908,0,0;QS=3,0;MQSB=0.934728;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,125:4:0 0,15,171:5:0 +X 918 . G <*> 0 . DP=19;I16=9,10,0,0,688,25456,0,0,1117,66169,0,0,314,6818,0,0;QS=3,0;MQSB=0.934728;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,129:4:0 0,15,147:5:0 +X 919 . C <*> 0 . DP=18;I16=8,10,0,0,672,25786,0,0,1057,62569,0,0,311,6751,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,92:3:0 0,15,152:5:0 +X 920 . T <*> 0 . DP=18;I16=8,10,0,0,681,26113,0,0,1057,62569,0,0,308,6706,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,95:3:0 0,15,171:5:0 +X 921 . G <*> 0 . DP=17;I16=7,10,0,0,617,22841,0,0,997,58969,0,0,304,6582,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,6,47:2:0 0,15,164:5:0 +X 922 . G <*> 0 . DP=16;I16=7,8,0,0,560,21156,0,0,877,51769,0,0,276,5852,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,24,243:8:0 0,6,64:2:0 0,15,151:5:0 +X 923 . G <*> 0 . DP=16;I16=7,8,0,0,562,21350,0,0,877,51769,0,0,273,5765,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,24,245:8:0 0,6,65:2:0 0,15,144:5:0 +X 924 . C <*> 0 . DP=16;I16=7,9,0,0,603,22955,0,0,937,55369,0,0,295,6321,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,6,57:2:0 0,15,157:5:0 +X 925 . A <*> 0 . DP=16;I16=7,9,0,0,576,21618,0,0,937,55369,0,0,291,6219,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,6,58:2:0 0,15,163:5:0 +X 926 . T <*> 0 . DP=16;I16=7,9,0,0,585,22015,0,0,937,55369,0,0,287,6133,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,6,63:2:0 0,15,161:5:0 +X 927 . G <*> 0 . DP=17;I16=7,10,0,0,641,24481,0,0,997,58969,0,0,283,6063,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,9,82:3:0 0,15,158:5:0 +X 928 . G <*> 0 . DP=17;I16=7,10,0,0,625,23195,0,0,997,58969,0,0,280,6010,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,9,84:3:0 0,15,150:5:0 +X 929 . T <*> 0 . DP=16;I16=7,9,0,0,580,21580,0,0,937,55369,0,0,277,5925,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,27,248:9:0 0,9,79:3:0 0,12,128:4:0 +X 930 . G <*> 0 . DP=16;I16=7,8,0,0,565,21561,0,0,877,51769,0,0,249,5233,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,24,247:8:0 0,9,82:3:0 0,12,127:4:0 +X 931 . G <*> 0 . DP=16;I16=7,9,0,0,553,19935,0,0,937,55369,0,0,271,5809,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,9,80:3:0 0,12,113:4:0 +X 932 . T <*> 0 . DP=16;I16=7,9,0,0,558,20128,0,0,937,55369,0,0,268,5778,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,27,229:9:0 0,9,89:3:0 0,12,122:4:0 +X 933 . G <*> 0 . DP=16;I16=7,8,0,0,558,20926,0,0,877,51769,0,0,239,5091,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,24,241:8:0 0,9,94:3:0 0,12,116:4:0 +X 934 . C <*> 0 . DP=15;I16=7,8,0,0,548,20256,0,0,877,51769,0,0,261,5673,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,9,83:3:0 0,9,99:3:0 +X 935 . A <*> 0 . DP=15;I16=7,8,0,0,534,19780,0,0,846,49010,0,0,259,5647,0,0;QS=3,0;MQSB=0.720273;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,9,86:3:0 0,9,101:3:0 +X 936 . T <*> 0 . DP=15;I16=7,8,0,0,579,22499,0,0,846,49010,0,0,257,5589,0,0;QS=3,0;MQSB=0.720273;MQ0F=0 PL:DP:DV 0,27,252:9:0 0,9,91:3:0 0,9,100:3:0 +X 937 . G <*> 0 . DP=16;I16=8,7,0,0,550,20650,0,0,846,49010,0,0,232,5022,0,0;QS=3,0;MQSB=0.651439;MQ0F=0 PL:DP:DV 0,24,228:8:0 0,9,84:3:0 0,12,115:4:0 +X 938 . C <*> 0 . DP=16;I16=8,7,0,0,553,20669,0,0,846,49010,0,0,231,5001,0,0;QS=3,0;MQSB=0.651439;MQ0F=0 PL:DP:DV 0,24,234:8:0 0,9,77:3:0 0,12,119:4:0 +X 939 . C <*> 0 . DP=16;I16=8,8,0,0,582,22100,0,0,906,52610,0,0,250,5392,0,0;QS=3,0;MQSB=0.702619;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,9,71:3:0 0,12,115:4:0 +X 940 . T <*> 0 . DP=15;I16=8,7,0,0,583,23339,0,0,846,49010,0,0,248,5320,0,0;QS=3,0;MQSB=0.651439;MQ0F=0 PL:DP:DV 0,27,252:9:0 0,6,71:2:0 0,12,124:4:0 +X 941 . G <*> 0 . DP=14;I16=7,7,0,0,501,18707,0,0,786,45410,0,0,246,5216,0,0;QS=3,0;MQSB=0.714506;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,6,59:2:0 0,9,93:3:0 +X 942 . T <*> 0 . DP=14;I16=7,7,0,0,525,19799,0,0,786,45410,0,0,244,5128,0,0;QS=3,0;MQSB=0.714506;MQ0F=0 PL:DP:DV 0,27,237:9:0 0,6,70:2:0 0,9,94:3:0 +X 943 . A <*> 0 . DP=14;I16=7,7,0,0,545,21399,0,0,786,45410,0,0,242,5056,0,0;QS=3,0;MQSB=0.714506;MQ0F=0 PL:DP:DV 0,27,248:9:0 0,6,71:2:0 0,9,93:3:0 +X 944 . G <*> 0 . DP=14;I16=7,7,0,0,529,20143,0,0,786,45410,0,0,240,5000,0,0;QS=3,0;MQSB=0.714506;MQ0F=0 PL:DP:DV 0,27,249:9:0 0,6,65:2:0 0,9,95:3:0 +X 945 . T <*> 0 . DP=14;I16=7,7,0,0,523,19621,0,0,786,45410,0,0,238,4960,0,0;QS=3,0;MQSB=0.714506;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,6,70:2:0 0,9,95:3:0 +X 946 . C <*> 0 . DP=13;I16=6,6,0,0,455,17581,0,0,666,38210,0,0,223,4739,0,0;QS=3,0;MQSB=0.660716;MQ0F=0 PL:DP:DV 0,24,240:8:0 0,6,56:2:0 0,6,70:2:0 +X 947 . C <*> 0 . DP=14;I16=7,7,0,0,509,19007,0,0,755,42651,0,0,238,4928,0,0;QS=3,0;MQSB=0.925999;MQ0F=0 PL:DP:DV 0,27,251:9:0 0,9,83:3:0 0,6,66:2:0 +X 948 . C <*> 0 . DP=14;I16=7,7,0,0,520,20050,0,0,755,42651,0,0,237,4887,0,0;QS=3,0;MQSB=0.925999;MQ0F=0 PL:DP:DV 0,27,254:9:0 0,9,78:3:0 0,6,69:2:0 +X 949 . A <*> 0 . DP=15;I16=7,8,0,0,547,20705,0,0,815,46251,0,0,236,4864,0,0;QS=3,0;MQSB=0.959011;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,9,90:3:0 0,6,72:2:0 +X 950 . G <*> 0 . DP=15;I16=6,8,0,0,563,22871,0,0,786,45410,0,0,231,4835,0,0;QS=3,0;MQSB=0.740818;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,6,71:2:0 0,6,72:2:0 +X 951 . C <*> 0 . DP=16;I16=7,8,0,0,554,21080,0,0,846,49010,0,0,230,4840,0,0;QS=3,0;MQSB=0.720273;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,65:2:0 0,6,73:2:0 +X 952 . T <*> 0 . DP=16;I16=8,8,0,0,595,22565,0,0,875,49851,0,0,237,4913,0,0;QS=3,0;MQSB=0.934676;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,93:3:0 0,6,73:2:0 +X 953 . A <*> 0 . DP=16;I16=8,8,0,0,567,20515,0,0,875,49851,0,0,237,4921,0,0;QS=3,0;MQSB=0.934676;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,91:3:0 0,6,69:2:0 +X 954 . T <*> 0 . DP=15;I16=7,8,0,0,544,20412,0,0,815,46251,0,0,238,4948,0,0;QS=3,0;MQSB=0.959011;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,9,94:3:0 0,6,69:2:0 +X 955 . T <*> 0 . DP=15;I16=7,8,0,0,543,19953,0,0,815,46251,0,0,239,4993,0,0;QS=3,0;MQSB=0.959011;MQ0F=0 PL:DP:DV 0,30,246:10:0 0,9,95:3:0 0,6,68:2:0 +X 956 . C <*> 0 . DP=15;I16=6,8,0,0,543,21255,0,0,786,45410,0,0,229,4935,0,0;QS=3,0;MQSB=0.740818;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,6,62:2:0 0,6,70:2:0 +X 957 . A <*> 0 . DP=15;I16=7,8,0,0,504,17684,0,0,815,46251,0,0,241,5137,0,0;QS=3,0;MQSB=0.959011;MQ0F=0 PL:DP:DV 0,30,240:10:0 0,9,74:3:0 0,6,67:2:0 +X 958 . C <*> 0 . DP=14;I16=6,8,0,0,505,18981,0,0,755,42651,0,0,243,5235,0,0;QS=3,0;MQSB=0.981425;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,9,78:3:0 0,3,39:1:0 +X 959 . A <*> 0 . DP=14;I16=5,8,0,0,519,20885,0,0,726,41810,0,0,231,5153,0,0;QS=3,0;MQSB=0.765017;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,6,72:2:0 0,3,38:1:0 +X 960 . G <*> 0 . DP=15;I16=6,9,0,0,539,19901,0,0,815,46251,0,0,247,5479,0,0;QS=3,0;MQSB=0.99308;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,106:4:0 0,3,41:1:0 +X 961 . T <*> 0 . DP=14;I16=6,8,0,0,523,19835,0,0,755,42651,0,0,250,5574,0,0;QS=3,0;MQSB=0.981425;MQ0F=0 PL:DP:DV 0,27,248:9:0 0,12,114:4:0 0,3,39:1:0 +X 962 . G <*> 0 . DP=14;I16=5,8,0,0,498,19194,0,0,726,41810,0,0,236,5394,0,0;QS=3,0;MQSB=0.765017;MQ0F=0 PL:DP:DV 0,27,253:9:0 0,9,91:3:0 0,3,36:1:0 +X 963 . C <*> 0 . DP=13;I16=5,8,0,0,500,19610,0,0,695,39051,0,0,256,5754,0,0;QS=3,0;MQSB=0.997325;MQ0F=0 PL:DP:DV 0,24,234:8:0 0,12,118:4:0 0,3,40:1:0 +X 964 . T <*> 0 . DP=13;I16=5,8,0,0,512,20430,0,0,695,39051,0,0,259,5835,0,0;QS=3,0;MQSB=0.997325;MQ0F=0 PL:DP:DV 0,24,227:8:0 0,12,128:4:0 0,3,42:1:0 +X 965 . G <*> 0 . DP=13;I16=4,8,0,0,467,18429,0,0,666,38210,0,0,241,5477,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,228:8:0 0,9,93:3:0 0,3,40:1:0 +X 966 . A <*> 0 . DP=13;I16=4,8,0,0,443,16785,0,0,666,38210,0,0,242,5490,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,212:8:0 0,9,95:3:0 0,3,40:1:0 +X 967 . G <*> 0 . DP=13;I16=4,8,0,0,464,18036,0,0,666,38210,0,0,243,5513,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,230:8:0 0,9,91:3:0 0,3,41:1:0 +X 968 . G <*> 0 . DP=13;I16=4,8,0,0,441,16549,0,0,666,38210,0,0,244,5546,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,218:8:0 0,9,87:3:0 0,3,42:1:0 +X 969 . T <*> 0 . DP=13;I16=4,8,0,0,450,16970,0,0,666,38210,0,0,245,5589,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,220:8:0 0,9,98:3:0 0,3,31:1:0 +X 970 . G <*> 0 . DP=13;I16=4,7,0,0,413,15579,0,0,629,36841,0,0,220,4968,0,0;QS=3,0;MQSB=0.924449;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,6,71:2:0 0,3,33:1:0 +X 971 . G <*> 0 . DP=13;I16=4,8,0,0,459,17711,0,0,666,38210,0,0,245,5609,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,223:8:0 0,9,93:3:0 0,3,38:1:0 +X 972 . G <*> 0 . DP=13;I16=4,8,0,0,446,17192,0,0,666,38210,0,0,245,5637,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,210:8:0 0,9,96:3:0 0,3,39:1:0 +X 973 . A <*> 0 . DP=12;I16=4,7,0,0,402,15018,0,0,606,34610,0,0,246,5676,0,0;QS=3,0;MQSB=0.763675;MQ0F=0 PL:DP:DV 0,21,192:7:0 0,9,89:3:0 0,3,42:1:0 +X 974 . A <*> 0 . DP=12;I16=4,7,0,0,417,16273,0,0,606,34610,0,0,247,5725,0,0;QS=3,0;MQSB=0.763675;MQ0F=0 PL:DP:DV 0,21,198:7:0 0,9,96:3:0 0,3,42:1:0 +X 975 . G <*> 0 . DP=13;I16=4,8,0,0,454,17560,0,0,666,38210,0,0,247,5733,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,213:8:0 0,9,95:3:0 0,3,42:1:0 +X 976 . A <*> 0 . DP=13;I16=4,8,0,0,431,16083,0,0,666,38210,0,0,248,5750,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,227:8:0 0,9,70:3:0 0,3,41:1:0 +X 977 . T <*> 0 . DP=13;I16=4,8,0,0,438,16316,0,0,666,38210,0,0,248,5726,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,210:8:0 0,9,93:3:0 0,3,37:1:0 +X 978 . G <*> 0 . DP=12;I16=4,8,0,0,430,16060,0,0,666,38210,0,0,248,5710,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,224:8:0 0,9,75:3:0 0,3,40:1:0 +X 979 . C <*> 0 . DP=13;I16=4,8,0,0,453,17461,0,0,689,40441,0,0,223,5077,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,27,232:9:0 0,6,72:2:0 0,3,41:1:0 +X 980 . T <*> 0 . DP=13;I16=4,8,0,0,438,16412,0,0,689,40441,0,0,224,5078,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,27,220:9:0 0,6,76:2:0 0,3,43:1:0 +X 981 . T <*> 0 . DP=13;I16=4,9,0,0,484,18602,0,0,726,41810,0,0,250,5714,0,0;QS=3,0;MQSB=0.826565;MQ0F=0 PL:DP:DV 0,27,224:9:0 0,9,97:3:0 0,3,41:1:0 +X 982 . G <*> 0 . DP=14;I16=4,10,0,0,520,20128,0,0,786,45410,0,0,250,5686,0,0;QS=3,0;MQSB=0.852144;MQ0F=0 PL:DP:DV 0,30,237:10:0 0,9,99:3:0 0,3,40:1:0 +X 983 . A <*> 0 . DP=14;I16=4,10,0,0,570,23360,0,0,786,45410,0,0,251,5671,0,0;QS=3,0;MQSB=0.852144;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,101:3:0 0,3,42:1:0 +X 984 . G <*> 0 . DP=15;I16=4,10,0,0,529,20459,0,0,786,45410,0,0,252,5670,0,0;QS=3,0;MQSB=0.852144;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,9,88:3:0 0,3,43:1:0 +X 985 . C <*> 0 . DP=17;I16=4,13,0,0,580,20280,0,0,966,56210,0,0,261,5747,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,33,246:11:0 0,12,100:4:0 0,6,65:2:0 +X 986 . C A,<*> 0 . DP=17;I16=3,12,0,1,519,18353,13,169,846,49010,60,3600,235,5101,4,16;QS=2.95873,0.0412698,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.921781;BQB=1;MQ0F=0 PL:DP:DV 0,16,197,27,200,201:10:1 0,12,108,12,108,108:4:0 0,6,69,6,69,69:2:0 +X 987 . C <*> 0 . DP=17;I16=4,13,0,0,634,23914,0,0,966,56210,0,0,267,5755,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,107:4:0 0,6,69:2:0 +X 988 . A <*> 0 . DP=17;I16=4,13,0,0,633,24341,0,0,966,56210,0,0,269,5737,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,111:4:0 0,6,82:2:0 +X 989 . G <*> 0 . DP=17;I16=4,13,0,0,635,24149,0,0,966,56210,0,0,271,5739,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,114:4:0 0,6,80:2:0 +X 990 . G <*> 0 . DP=16;I16=4,12,0,0,591,22177,0,0,906,52610,0,0,274,5760,0,0;QS=3,0;MQSB=0.88901;MQ0F=0 PL:DP:DV 0,30,246:10:0 0,12,105:4:0 0,6,83:2:0 +X 991 . A <*> 0 . DP=16;I16=3,11,0,0,548,21542,0,0,809,47641,0,0,227,4549,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,27,232:9:0 0,9,100:3:0 0,6,80:2:0 +X 992 . G <*> 0 . DP=16;I16=4,12,0,0,562,20436,0,0,906,52610,0,0,278,5760,0,0;QS=3,0;MQSB=0.88901;MQ0F=0 PL:DP:DV 0,30,240:10:0 0,12,102:4:0 0,6,76:2:0 +X 993 . T <*> 0 . DP=16;I16=4,12,0,0,564,20752,0,0,906,52610,0,0,280,5790,0,0;QS=3,0;MQSB=0.88901;MQ0F=0 PL:DP:DV 0,30,222:10:0 0,12,121:4:0 0,6,73:2:0 +X 994 . T <*> 0 . DP=17;I16=5,11,0,0,597,22625,0,0,906,52610,0,0,270,5696,0,0;QS=3,0;MQSB=0.851779;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,12,123:4:0 0,9,103:3:0 +X 995 . C <*> 0 . DP=16;I16=4,11,0,0,588,23228,0,0,846,49010,0,0,273,5741,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,24,216:8:0 0,12,119:4:0 0,9,110:3:0 +X 996 . A <*> 0 . DP=16;I16=4,12,0,0,562,20416,0,0,906,52610,0,0,290,6000,0,0;QS=3,0;MQSB=0.88901;MQ0F=0 PL:DP:DV 0,27,207:9:0 0,12,107:4:0 0,9,113:3:0 +X 997 . A <*> 0 . DP=16;I16=4,12,0,0,600,23520,0,0,906,52610,0,0,294,6110,0,0;QS=3,0;MQSB=0.88901;MQ0F=0 PL:DP:DV 0,27,209:9:0 0,12,123:4:0 0,9,121:3:0 +X 998 . G <*> 0 . DP=17;I16=4,13,0,0,603,22299,0,0,966,56210,0,0,298,6240,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,30,226:10:0 0,12,99:4:0 0,9,115:3:0 +X 999 . G <*> 0 . DP=17;I16=4,12,0,0,575,21519,0,0,906,52610,0,0,302,6390,0,0;QS=3,0;MQSB=0.88901;MQ0F=0 PL:DP:DV 0,27,202:9:0 0,12,118:4:0 0,9,111:3:0 +X 1000 . C <*> 0 . DP=17;I16=4,13,0,0,637,24465,0,0,966,56210,0,0,308,6564,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,30,235:10:0 0,12,118:4:0 0,9,109:3:0 +X 1001 . T <*> 0 . DP=17;I16=4,13,0,0,647,24907,0,0,966,56210,0,0,312,6708,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,30,228:10:0 0,12,120:4:0 0,9,122:3:0 +X 1002 . G <*> 0 . DP=17;I16=4,13,0,0,627,23691,0,0,966,56210,0,0,316,6872,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,30,220:10:0 0,12,123:4:0 0,9,109:3:0 +X 1003 . C T,<*> 0 . DP=18;I16=4,13,0,1,633,23953,22,484,966,56210,60,3600,297,6515,21,441;QS=2.9375,0.0625,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.913725;BQB=1;MQ0F=0 PL:DP:DV 0,8,207,27,211,220:10:1 0,15,132,15,132,132:5:0 0,9,102,9,102,102:3:0 +X 1004 . A <*> 0 . DP=19;I16=5,14,0,0,653,23107,0,0,1086,63410,0,0,321,7061,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,231:11:0 0,15,131:5:0 0,9,98:3:0 +X 1005 . A <*> 0 . DP=19;I16=5,14,0,0,670,24380,0,0,1086,63410,0,0,324,7138,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,231:11:0 0,15,132:5:0 0,9,113:3:0 +X 1006 . T <*> 0 . DP=19;I16=4,14,0,0,659,24869,0,0,1026,59810,0,0,327,7237,0,0;QS=3,0;MQSB=0.913725;MQ0F=0 PL:DP:DV 0,30,220:10:0 0,15,134:5:0 0,9,115:3:0 +X 1007 . G <*> 0 . DP=18;I16=4,13,0,0,651,25373,0,0,966,56210,0,0,306,6732,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,27,225:9:0 0,15,138:5:0 0,9,113:3:0 +X 1008 . A <*> 0 . DP=18;I16=4,13,0,0,667,27041,0,0,966,56210,0,0,309,6821,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,27,222:9:0 0,15,147:5:0 0,9,118:3:0 +X 1009 . G <*> 0 . DP=18;I16=4,13,0,0,635,24431,0,0,966,56210,0,0,312,6928,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,27,213:9:0 0,15,139:5:0 0,9,116:3:0 +X 1010 . C <*> 0 . DP=18;I16=4,14,0,0,661,25289,0,0,1026,59810,0,0,339,7629,0,0;QS=3,0;MQSB=0.913725;MQ0F=0 PL:DP:DV 0,30,234:10:0 0,15,126:5:0 0,9,114:3:0 +X 1011 . T <*> 0 . DP=18;I16=4,14,0,0,671,25325,0,0,1026,59810,0,0,339,7623,0,0;QS=3,0;MQSB=0.913725;MQ0F=0 PL:DP:DV 0,30,226:10:0 0,15,131:5:0 0,9,118:3:0 +X 1012 . A <*> 0 . DP=19;I16=5,14,0,0,639,22891,0,0,1063,61179,0,0,339,7633,0,0;QS=3,0;MQSB=0.990403;MQ0F=0 PL:DP:DV 0,30,201:10:0 0,18,154:6:0 0,9,113:3:0 +X 1013 . T <*> 0 . DP=18;I16=5,12,0,0,623,23913,0,0,943,53979,0,0,325,7385,0,0;QS=3,0;MQSB=0.998612;MQ0F=0 PL:DP:DV 0,24,202:8:0 0,18,161:6:0 0,9,115:3:0 +X 1014 . G <*> 0 . DP=18;I16=5,13,0,0,656,24596,0,0,1003,57579,0,0,341,7605,0,0;QS=3,0;MQSB=0.995153;MQ0F=0 PL:DP:DV 0,27,218:9:0 0,18,159:6:0 0,9,113:3:0 +X 1015 . A <*> 0 . DP=18;I16=5,13,0,0,646,23878,0,0,1003,57579,0,0,342,7618,0,0;QS=3,0;MQSB=0.995153;MQ0F=0 PL:DP:DV 0,27,209:9:0 0,18,164:6:0 0,9,109:3:0 +X 1016 . T <*> 0 . DP=17;I16=4,12,0,0,588,22114,0,0,929,54841,0,0,340,7632,0,0;QS=3,0;MQSB=0.971017;MQ0F=0 PL:DP:DV 0,27,212:9:0 0,12,124:4:0 0,9,101:3:0 +X 1017 . T <*> 0 . DP=18;I16=5,13,0,0,635,23433,0,0,1026,59810,0,0,346,7694,0,0;QS=3,0;MQSB=0.942222;MQ0F=0 PL:DP:DV 0,27,213:9:0 0,18,155:6:0 0,9,105:3:0 +X 1018 . G <*> 0 . DP=18;I16=5,13,0,0,650,24550,0,0,1026,59810,0,0,349,7757,0,0;QS=3,0;MQSB=0.942222;MQ0F=0 PL:DP:DV 0,27,215:9:0 0,18,179:6:0 0,9,91:3:0 +X 1019 . C <*> 0 . DP=18;I16=5,12,0,0,555,18561,0,0,966,56210,0,0,327,7213,0,0;QS=3,0;MQSB=0.951229;MQ0F=0 PL:DP:DV 0,24,181:8:0 0,18,143:6:0 0,9,104:3:0 +X 1020 . G <*> 0 . DP=19;I16=6,12,0,0,625,22287,0,0,1026,59810,0,0,332,7402,0,0;QS=3,0;MQSB=0.97296;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,18,157:6:0 0,9,87:3:0 +X 1021 . C <*> 0 . DP=19;I16=5,13,0,0,625,22761,0,0,1026,59810,0,0,332,7326,0,0;QS=3,0;MQSB=0.942222;MQ0F=0 PL:DP:DV 0,27,220:9:0 0,18,153:6:0 0,9,92:3:0 +X 1022 . C <*> 0 . DP=19;I16=6,13,0,0,727,27975,0,0,1086,63410,0,0,360,8034,0,0;QS=3,0;MQSB=0.965977;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,168:6:0 0,9,110:3:0 +X 1023 . A <*> 0 . DP=19;I16=6,12,0,0,647,23997,0,0,1026,59810,0,0,338,7510,0,0;QS=3,0;MQSB=0.97296;MQ0F=0 PL:DP:DV 0,27,216:9:0 0,18,168:6:0 0,9,112:3:0 +X 1024 . C <*> 0 . DP=20;I16=7,13,0,0,729,27471,0,0,1146,67010,0,0,364,8154,0,0;QS=3,0;MQSB=0.980568;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,169:6:0 0,9,106:3:0 +X 1025 . T <*> 0 . DP=20;I16=7,13,0,0,757,29387,0,0,1146,67010,0,0,366,8192,0,0;QS=3,0;MQSB=0.980568;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,181:6:0 0,9,117:3:0 +X 1026 . G <*> 0 . DP=20;I16=7,13,0,0,747,28435,0,0,1146,67010,0,0,367,8201,0,0;QS=3,0;MQSB=0.980568;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,169:6:0 0,9,113:3:0 +X 1027 . C <*> 0 . DP=20;I16=7,13,0,0,720,26688,0,0,1146,67010,0,0,368,8232,0,0;QS=3,0;MQSB=0.980568;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,145:6:0 0,9,110:3:0 +X 1028 . A <*> 0 . DP=19;I16=6,12,0,0,645,23681,0,0,1026,59810,0,0,348,7800,0,0;QS=3,0;MQSB=0.97296;MQ0F=0 PL:DP:DV 0,30,238:10:0 0,15,146:5:0 0,9,99:3:0 +X 1029 . C <*> 0 . DP=19;I16=7,12,0,0,699,26817,0,0,1086,63410,0,0,371,8305,0,0;QS=3,0;MQSB=0.985816;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,138:5:0 0,9,111:3:0 +X 1030 . T <*> 0 . DP=19;I16=7,12,0,0,749,29789,0,0,1086,63410,0,0,371,8293,0,0;QS=3,0;MQSB=0.985816;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,158:5:0 0,9,122:3:0 +X 1031 . T <*> 0 . DP=21;I16=9,12,0,0,748,27726,0,0,1206,70610,0,0,371,8297,0,0;QS=3,0;MQSB=0.997478;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,144:5:0 0,9,113:3:0 +X 1032 . T <*> 0 . DP=21;I16=9,12,0,0,761,28033,0,0,1206,70610,0,0,373,8319,0,0;QS=3,0;MQSB=0.997478;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,156:5:0 0,9,111:3:0 +X 1033 . G <*> 0 . DP=22;I16=10,12,0,0,773,28227,0,0,1266,74210,0,0,375,8361,0,0;QS=3,0;MQSB=0.999457;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,169:6:0 0,9,101:3:0 +X 1034 . G <*> 0 . DP=22;I16=8,12,0,0,703,25617,0,0,1169,69241,0,0,340,7684,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,149:5:0 0,9,102:3:0 +X 1035 . C <*> 0 . DP=21;I16=10,11,0,0,719,26103,0,0,1237,73369,0,0,382,8508,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,163:6:0 0,9,94:3:0 +X 1036 . C <*> 0 . DP=22;I16=11,10,0,0,756,28390,0,0,1237,73369,0,0,360,7938,0,0;QS=3,0;MQSB=0.939898;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,175:6:0 0,12,135:4:0 +X 1037 . T <*> 0 . DP=22;I16=11,11,0,0,839,32737,0,0,1297,76969,0,0,389,8641,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,188:6:0 0,12,138:4:0 +X 1038 . G <*> 0 . DP=21;I16=10,10,0,0,752,28750,0,0,1177,69769,0,0,368,8066,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,184:6:0 0,9,107:3:0 +X 1039 . G <*> 0 . DP=21;I16=10,11,0,0,775,29373,0,0,1237,73369,0,0,397,8761,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,189:6:0 0,9,111:3:0 +X 1040 . A <*> 0 . DP=21;I16=10,11,0,0,759,28007,0,0,1237,73369,0,0,401,8851,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,177:6:0 0,9,107:3:0 +X 1041 . C <*> 0 . DP=21;I16=8,11,0,0,713,27117,0,0,1140,68400,0,0,371,8255,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,155:5:0 0,9,110:3:0 +X 1042 . A <*> 0 . DP=23;I16=12,10,0,0,800,29464,0,0,1297,76969,0,0,384,8466,0,0;QS=3,0;MQSB=0.947103;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,185:6:0 0,15,145:5:0 +X 1043 . A <*> 0 . DP=23;I16=12,11,0,0,850,32160,0,0,1357,80569,0,0,414,9192,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,188:6:0 0,15,159:5:0 +X 1044 . C <*> 0 . DP=23;I16=12,10,0,0,812,30758,0,0,1297,76969,0,0,394,8690,0,0;QS=3,0;MQSB=0.947103;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,181:6:0 0,15,150:5:0 +X 1045 . A <*> 0 . DP=23;I16=12,11,0,0,887,34519,0,0,1357,80569,0,0,424,9460,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,197:6:0 0,15,156:5:0 +X 1046 . G <*> 0 . DP=23;I16=12,11,0,0,862,33240,0,0,1357,80569,0,0,428,9576,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,183:6:0 0,15,158:5:0 +X 1047 . A <*> 0 . DP=23;I16=12,11,0,0,890,34804,0,0,1357,80569,0,0,432,9712,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,198:6:0 0,15,165:5:0 +X 1048 . G <*> 0 . DP=23;I16=12,10,0,0,846,33054,0,0,1297,76969,0,0,411,9243,0,0;QS=3,0;MQSB=0.947103;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,195:6:0 0,15,156:5:0 +X 1049 . C <*> 0 . DP=22;I16=12,10,0,0,808,30644,0,0,1297,76969,0,0,441,10043,0,0;QS=3,0;MQSB=0.947103;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,182:6:0 0,15,160:5:0 +X 1050 . A <*> 0 . DP=22;I16=11,10,0,0,808,31334,0,0,1237,73369,0,0,430,9940,0,0;QS=3,0;MQSB=0.939898;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,193:6:0 0,12,138:4:0 +X 1051 . A <*> 0 . DP=21;I16=11,9,0,0,731,27495,0,0,1177,69769,0,0,423,9621,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,18,187:6:0 0,15,150:5:0 +X 1052 . A <*> 0 . DP=21;I16=11,9,0,0,759,29327,0,0,1177,69769,0,0,427,9747,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,27,247:9:0 0,18,190:6:0 0,15,150:5:0 +X 1053 . A <*> 0 . DP=21;I16=11,8,0,0,674,25210,0,0,1117,66169,0,0,406,9264,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,24,224:8:0 0,18,161:6:0 0,15,149:5:0 +X 1054 . C <*> 0 . DP=21;I16=11,10,0,0,791,30157,0,0,1237,73369,0,0,459,10623,0,0;QS=3,0;MQSB=0.939898;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,189:6:0 0,15,153:5:0 +X 1055 . C <*> 0 . DP=22;I16=12,10,0,0,818,31448,0,0,1297,76969,0,0,462,10750,0,0;QS=3,0;MQSB=0.947103;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,191:6:0 0,15,157:5:0 +X 1056 . C <*> 0 . DP=22;I16=12,9,0,0,793,31265,0,0,1237,73369,0,0,441,10271,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,195:6:0 0,15,161:5:0 +X 1057 . T <*> 0 . DP=23;I16=12,10,0,0,821,31667,0,0,1297,76969,0,0,467,10911,0,0;QS=3,0;MQSB=0.947103;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,196:6:0 0,15,159:5:0 +X 1058 . G <*> 0 . DP=23;I16=12,11,0,0,863,32871,0,0,1357,80569,0,0,493,11569,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,197:7:0 0,15,155:5:0 +X 1059 . T <*> 0 . DP=23;I16=12,10,0,0,797,29803,0,0,1297,76969,0,0,468,10944,0,0;QS=3,0;MQSB=0.947103;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,21,202:7:0 0,15,152:5:0 +X 1060 . C <*> 0 . DP=23;I16=12,11,0,0,829,31041,0,0,1357,80569,0,0,492,11536,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,178:7:0 0,15,163:5:0 +X 1061 . T <*> 0 . DP=22;I16=12,9,0,0,810,31840,0,0,1237,73369,0,0,465,10797,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,175:5:0 0,15,158:5:0 +X 1062 . C A,<*> 0 . DP=22;I16=12,9,0,1,826,32780,33,1089,1237,73369,60,3600,462,10652,25,625;QS=2.85398,0.146018,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.947103;BQB=1;MQ0F=0 PL:DP:DV 0,33,255,33,255,255:11:0 15,0,151,30,154,176:6:1 0,15,164,15,164,164:5:0 +X 1063 . T <*> 0 . DP=22;I16=12,9,0,0,820,32460,0,0,1237,73369,0,0,459,10525,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,183:6:0 0,15,166:5:0 +X 1064 . A <*> 0 . DP=23;I16=12,9,0,0,793,30355,0,0,1237,73369,0,0,464,10752,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,180:6:0 0,15,162:5:0 +X 1065 . A <*> 0 . DP=23;I16=12,9,0,0,814,31978,0,0,1237,73369,0,0,462,10694,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,186:6:0 0,15,174:5:0 +X 1066 . A <*> 0 . DP=27;I16=15,9,0,0,890,34378,0,0,1417,84169,0,0,460,10652,0,0;QS=3,0;MQSB=0.96464;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,198:7:0 0,18,181:6:0 +X 1067 . A <*> 0 . DP=27;I16=15,10,0,0,913,35031,0,0,1477,87769,0,0,470,10600,0,0;QS=3,0;MQSB=0.962269;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,208:7:0 0,18,182:6:0 +X 1068 . A <*> 0 . DP=27;I16=15,9,0,0,898,34580,0,0,1417,84169,0,0,456,10342,0,0;QS=3,0;MQSB=0.96464;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,24,218:8:0 0,18,181:6:0 +X 1069 . A <*> 0 . DP=28;I16=16,10,0,0,914,33888,0,0,1537,91369,0,0,481,10925,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,207:8:0 0,21,177:7:0 +X 1070 . A <*> 0 . DP=28;I16=15,11,0,0,955,36445,0,0,1537,91369,0,0,467,10351,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,223:8:0 0,21,188:7:0 +X 1071 . G <*> 0 . DP=28;I16=16,10,0,0,974,37570,0,0,1537,91369,0,0,466,10284,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,192:7:0 0,21,191:7:0 +X 1072 . A <*> 0 . DP=28;I16=16,11,0,0,1007,38205,0,0,1597,94969,0,0,490,10868,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,239:8:0 0,21,195:7:0 +X 1073 . A <*> 0 . DP=28;I16=16,10,0,0,976,37822,0,0,1537,91369,0,0,463,10177,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,24,236:8:0 0,21,199:7:0 +X 1074 . A <*> 0 . DP=28;I16=16,11,0,0,1003,38097,0,0,1597,94969,0,0,484,10664,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,232:8:0 0,21,203:7:0 +X 1075 . A <*> 0 . DP=28;I16=16,10,0,0,964,36762,0,0,1537,91369,0,0,476,10564,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,222:8:0 0,21,200:7:0 +X 1076 . G <*> 0 . DP=28;I16=16,10,0,0,966,37048,0,0,1537,91369,0,0,476,10536,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,209:8:0 0,21,183:7:0 +X 1077 . A <*> 0 . DP=29;I16=17,11,0,0,1038,39240,0,0,1657,98569,0,0,480,10548,0,0;QS=3,0;MQSB=0.967085;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,231:8:0 0,24,209:8:0 +X 1078 . A <*> 0 . DP=29;I16=17,11,0,0,1053,40425,0,0,1657,98569,0,0,480,10562,0,0;QS=3,0;MQSB=0.967085;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,234:8:0 0,24,214:8:0 +X 1079 . A <*> 0 . DP=28;I16=17,10,0,0,1019,39007,0,0,1597,94969,0,0,479,10505,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,223:8:0 0,24,206:8:0 +X 1080 . A <*> 0 . DP=29;I16=18,10,0,0,1049,40827,0,0,1657,98569,0,0,478,10478,0,0;QS=3,0;MQSB=0.971673;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,246:9:0 0,24,218:8:0 +X 1081 . G <*> 0 . DP=30;I16=19,8,0,0,988,37392,0,0,1597,94969,0,0,436,9550,0,0;QS=3,0;MQSB=0.977696;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,210:8:0 0,27,210:9:0 +X 1082 . A <*> 0 . DP=30;I16=20,7,0,0,989,37109,0,0,1597,94969,0,0,438,9564,0,0;QS=3,0;MQSB=0.981425;MQ0F=0 PL:DP:DV 0,27,224:9:0 0,27,226:9:0 0,27,217:9:0 +X 1083 . A <*> 0 . DP=30;I16=20,8,0,0,1039,39827,0,0,1657,98569,0,0,455,9803,0,0;QS=3,0;MQSB=0.979523;MQ0F=0 PL:DP:DV 0,30,246:10:0 0,27,233:9:0 0,27,217:9:0 +X 1084 . A <*> 0 . DP=31;I16=21,8,0,0,1049,39097,0,0,1717,102169,0,0,457,9849,0,0;QS=3,0;MQSB=0.981133;MQ0F=0 PL:DP:DV 0,33,253:11:0 0,27,226:9:0 0,27,215:9:0 +X 1085 . A <*> 0 . DP=30;I16=21,8,0,0,1052,39534,0,0,1717,102169,0,0,486,10552,0,0;QS=3,0;MQSB=0.981133;MQ0F=0 PL:DP:DV 0,30,232:10:0 0,30,247:10:0 0,27,214:9:0 +X 1086 . A <*> 0 . DP=28;I16=21,6,0,0,969,36223,0,0,1597,94969,0,0,492,10660,0,0;QS=3,0;MQSB=0.98481;MQ0F=0 PL:DP:DV 0,30,219:10:0 0,27,236:9:0 0,24,179:8:0 +X 1087 . C <*> 0 . DP=28;I16=22,6,0,0,984,36046,0,0,1657,98569,0,0,498,10796,0,0;QS=3,0;MQSB=0.985992;MQ0F=0 PL:DP:DV 0,30,234:10:0 0,27,229:9:0 0,27,173:9:0 +X 1088 . T <*> 0 . DP=29;I16=23,6,0,0,1133,45203,0,0,1717,102169,0,0,503,10863,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,30,250:10:0 0,27,198:9:0 +X 1089 . C <*> 0 . DP=29;I16=23,6,0,0,1093,42347,0,0,1717,102169,0,0,509,10965,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,30,237:10:0 0,27,188:9:0 +X 1090 . A <*> 0 . DP=29;I16=23,6,0,0,1061,39845,0,0,1717,102169,0,0,515,11103,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,221:10:0 0,30,250:10:0 0,27,183:9:0 +X 1091 . C <*> 0 . DP=29;I16=23,6,0,0,1063,39713,0,0,1717,102169,0,0,521,11277,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,30,244:10:0 0,27,177:9:0 +X 1092 . T <*> 0 . DP=29;I16=23,6,0,0,1121,44489,0,0,1717,102169,0,0,524,11334,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,244:10:0 0,30,251:10:0 0,27,198:9:0 +X 1093 . G <*> 0 . DP=29;I16=23,6,0,0,1085,41377,0,0,1717,102169,0,0,526,11372,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,30,243:10:0 0,27,184:9:0 +X 1094 . G <*> 0 . DP=29;I16=22,6,0,0,1018,38808,0,0,1657,98569,0,0,521,11393,0,0;QS=3,0;MQSB=0.985992;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,30,232:10:0 0,24,185:8:0 +X 1095 . A <*> 0 . DP=28;I16=22,6,0,0,1023,38551,0,0,1657,98569,0,0,529,11443,0,0;QS=3,0;MQSB=0.985992;MQ0F=0 PL:DP:DV 0,30,236:10:0 0,30,244:10:0 0,24,178:8:0 +X 1096 . T <*> 0 . DP=30;I16=24,5,0,0,1020,37168,0,0,1717,102169,0,0,505,10849,0,0;QS=3,0;MQSB=0.989637;MQ0F=0 PL:DP:DV 0,33,234:11:0 0,27,220:9:0 0,27,178:9:0 +X 1097 . A <*> 0 . DP=30;I16=24,6,0,0,1056,38166,0,0,1777,105769,0,0,533,11537,0,0;QS=3,0;MQSB=0.987976;MQ0F=0 PL:DP:DV 0,33,230:11:0 0,30,237:10:0 0,27,177:9:0 +X 1098 . T <*> 0 . DP=29;I16=24,5,0,0,1081,40557,0,0,1717,102169,0,0,537,11633,0,0;QS=3,0;MQSB=0.989637;MQ0F=0 PL:DP:DV 0,30,210:10:0 0,30,251:10:0 0,27,186:9:0 +X 1099 . G <*> 0 . DP=29;I16=24,5,0,0,1091,41719,0,0,1717,102169,0,0,540,11712,0,0;QS=3,0;MQSB=0.989637;MQ0F=0 PL:DP:DV 0,30,229:10:0 0,30,242:10:0 0,27,182:9:0 +X 1100 . A <*> 0 . DP=29;I16=24,5,0,0,1106,42976,0,0,1717,102169,0,0,543,11825,0,0;QS=3,0;MQSB=0.989637;MQ0F=0 PL:DP:DV 0,30,210:10:0 0,30,255:10:0 0,27,191:9:0 +X 1101 . A <*> 0 . DP=29;I16=24,5,0,0,1154,46420,0,0,1717,102169,0,0,545,11921,0,0;QS=3,0;MQSB=0.989637;MQ0F=0 PL:DP:DV 0,30,222:10:0 0,30,255:10:0 0,27,198:9:0 +X 1102 . T <*> 0 . DP=29;I16=24,4,0,0,1046,39520,0,0,1657,98569,0,0,522,11424,0,0;QS=3,0;MQSB=0.991416;MQ0F=0 PL:DP:DV 0,30,210:10:0 0,27,233:9:0 0,27,186:9:0 +X 1103 . G <*> 0 . DP=30;I16=24,6,0,0,1134,43486,0,0,1777,105769,0,0,548,12158,0,0;QS=3,0;MQSB=0.987976;MQ0F=0 PL:DP:DV 0,30,223:10:0 0,30,255:10:0 0,30,222:10:0 +X 1104 . A <*> 0 . DP=28;I16=23,5,0,0,1089,43067,0,0,1657,98569,0,0,552,12296,0,0;QS=3,0;MQSB=0.988819;MQ0F=0 PL:DP:DV 0,27,213:9:0 0,27,233:9:0 0,30,233:10:0 +X 1105 . T <*> 0 . DP=28;I16=23,5,0,0,1035,38743,0,0,1657,98569,0,0,556,12462,0,0;QS=3,0;MQSB=0.988819;MQ0F=0 PL:DP:DV 0,27,203:9:0 0,27,227:9:0 0,30,222:10:0 +X 1106 . A <*> 0 . DP=29;I16=23,5,0,0,1003,36715,0,0,1657,98569,0,0,532,11882,0,0;QS=3,0;MQSB=0.988819;MQ0F=0 PL:DP:DV 0,30,227:10:0 0,24,198:8:0 0,30,217:10:0 +X 1107 . C <*> 0 . DP=29;I16=23,6,0,0,1093,41509,0,0,1717,102169,0,0,558,12532,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,244:10:0 0,27,233:9:0 0,30,220:10:0 +X 1108 . A <*> 0 . DP=29;I16=23,6,0,0,1138,44908,0,0,1717,102169,0,0,558,12536,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,239:10:0 0,27,253:9:0 0,30,227:10:0 +X 1109 . G <*> 0 . DP=29;I16=23,6,0,0,1140,45200,0,0,1717,102169,0,0,557,12519,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,27,240:9:0 0,30,224:10:0 +X 1110 . G <*> 0 . DP=29;I16=23,6,0,0,1086,41054,0,0,1717,102169,0,0,555,12481,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,242:10:0 0,27,229:9:0 0,30,224:10:0 +X 1111 . T <*> 0 . DP=29;I16=22,6,0,0,1025,37919,0,0,1680,100800,0,0,552,12470,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,227:10:0 0,24,227:8:0 0,30,211:10:0 +X 1112 . T <*> 0 . DP=28;I16=22,6,0,0,1034,38986,0,0,1680,100800,0,0,550,12440,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,226:10:0 0,24,221:8:0 0,30,221:10:0 +X 1113 . G <*> 0 . DP=28;I16=23,5,0,0,1085,42273,0,0,1680,100800,0,0,548,12386,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,202:7:0 0,33,222:11:0 +X 1114 . A <*> 0 . DP=28;I16=23,5,0,0,1079,42279,0,0,1680,100800,0,0,546,12306,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,235:10:0 0,21,209:7:0 0,33,238:11:0 +X 1115 . G <*> 0 . DP=28;I16=23,5,0,0,1114,44550,0,0,1680,100800,0,0,544,12250,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,208:7:0 0,33,234:11:0 +X 1116 . G <*> 0 . DP=29;I16=24,5,0,0,1059,39531,0,0,1740,104400,0,0,542,12218,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,236:10:0 0,24,204:8:0 0,33,226:11:0 +X 1117 . A <*> 0 . DP=29;I16=24,5,0,0,1124,43896,0,0,1740,104400,0,0,541,12211,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,235:10:0 0,24,227:8:0 0,33,234:11:0 +X 1118 . T <*> 0 . DP=29;I16=24,4,0,0,1100,44802,0,0,1680,100800,0,0,539,12131,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,230:10:0 0,21,188:7:0 0,33,248:11:0 +X 1119 . C <*> 0 . DP=29;I16=23,4,0,0,1078,44864,0,0,1620,97200,0,0,526,11958,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,224:9:0 0,21,191:7:0 0,33,255:11:0 +X 1120 . C <*> 0 . DP=29;I16=23,5,0,0,1113,46071,0,0,1680,100800,0,0,536,12054,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,24,214:8:0 0,33,255:11:0 +X 1121 . A <*> 0 . DP=30;I16=24,5,0,0,1167,48549,0,0,1740,104400,0,0,536,12056,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,24,220:8:0 0,36,255:12:0 +X 1122 . T <*> 0 . DP=32;I16=26,5,0,0,1235,50967,0,0,1860,111600,0,0,535,11985,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,230:10:0 0,27,238:9:0 0,36,255:12:0 +X 1123 . T <*> 0 . DP=32;I16=26,5,0,0,1219,50121,0,0,1860,111600,0,0,535,11893,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,221:10:0 0,27,236:9:0 0,36,255:12:0 +X 1124 . A <*> 0 . DP=31;I16=25,5,0,0,1187,48827,0,0,1800,108000,0,0,536,11832,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,218:9:0 0,27,235:9:0 0,36,255:12:0 +X 1125 . T <*> 0 . DP=31;I16=25,5,0,0,1211,51001,0,0,1800,108000,0,0,537,11801,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,27,235:9:0 0,36,255:12:0 +X 1126 . C <*> 0 . DP=31;I16=25,5,0,0,1225,52001,0,0,1800,108000,0,0,538,11800,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,234:9:0 0,27,241:9:0 0,36,255:12:0 +X 1127 . T <*> 0 . DP=31;I16=25,5,0,0,1257,55245,0,0,1800,108000,0,0,539,11829,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,231:9:0 0,27,252:9:0 0,36,255:12:0 +X 1128 . G <*> 0 . DP=31;I16=25,5,0,0,1217,51743,0,0,1800,108000,0,0,540,11888,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,236:9:0 0,27,229:9:0 0,36,255:12:0 +X 1129 . A G,<*> 0 . DP=31;I16=24,4,0,1,1101,45631,32,1024,1680,100800,60,3600,514,11300,25,625;QS=2.93535,0.0646465,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,24,204,24,204,204:8:0 0,27,229,27,229,229:9:0 0,4,198,33,201,219:12:1 +X 1130 . A <*> 0 . DP=31;I16=25,5,0,0,1189,49509,0,0,1800,108000,0,0,539,11943,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,215:9:0 0,27,236:9:0 0,36,255:12:0 +X 1131 . A <*> 0 . DP=29;I16=23,5,0,0,1156,49362,0,0,1680,100800,0,0,540,11988,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,206:7:0 0,27,250:9:0 0,36,255:12:0 +X 1132 . T <*> 0 . DP=29;I16=23,5,0,0,1123,47359,0,0,1680,100800,0,0,540,12008,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,198:7:0 0,27,229:9:0 0,36,255:12:0 +X 1133 . G <*> 0 . DP=30;I16=23,5,0,0,1148,48796,0,0,1680,100800,0,0,540,12052,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,214:7:0 0,27,232:9:0 0,36,255:12:0 +X 1134 . C <*> 0 . DP=29;I16=22,6,0,0,1162,50224,0,0,1680,100800,0,0,547,12155,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,209:7:0 0,27,254:9:0 0,36,255:12:0 +X 1135 . T <*> 0 . DP=29;I16=22,6,0,0,1214,55020,0,0,1680,100800,0,0,549,12257,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,209:7:0 0,27,255:9:0 0,36,255:12:0 +X 1136 . T <*> 0 . DP=29;I16=22,6,0,0,1148,49270,0,0,1680,100800,0,0,551,12383,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,200:7:0 0,27,255:9:0 0,36,255:12:0 +X 1137 . G <*> 0 . DP=28;I16=21,6,0,0,1087,46051,0,0,1620,97200,0,0,554,12532,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,214:7:0 0,27,234:9:0 0,33,254:11:0 +X 1138 . G <*> 0 . DP=28;I16=21,6,0,0,1040,42504,0,0,1620,97200,0,0,557,12703,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,197:7:0 0,27,234:9:0 0,33,246:11:0 +X 1139 . A <*> 0 . DP=28;I16=21,6,0,0,1103,47389,0,0,1620,97200,0,0,559,12845,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,200:7:0 0,27,254:9:0 0,33,255:11:0 +X 1140 . C <*> 0 . DP=28;I16=21,6,0,0,1072,44372,0,0,1620,97200,0,0,561,13007,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,214:7:0 0,27,234:9:0 0,33,250:11:0 +X 1141 . C <*> 0 . DP=28;I16=21,6,0,0,1106,47298,0,0,1620,97200,0,0,562,13140,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,212:7:0 0,27,245:9:0 0,33,255:11:0 +X 1142 . A <*> 0 . DP=28;I16=21,6,0,0,1114,47788,0,0,1620,97200,0,0,560,13146,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,212:7:0 0,27,255:9:0 0,33,251:11:0 +X 1143 . G <*> 0 . DP=26;I16=19,7,0,0,1041,42249,0,0,1560,93600,0,0,585,13799,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,222:7:0 0,27,249:9:0 0,30,253:10:0 +X 1144 . A <*> 0 . DP=26;I16=19,7,0,0,1018,40154,0,0,1560,93600,0,0,585,13847,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,205:7:0 0,27,250:9:0 0,30,255:10:0 +X 1145 . T <*> 0 . DP=26;I16=19,7,0,0,1016,39852,0,0,1560,93600,0,0,584,13866,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,206:7:0 0,27,250:9:0 0,30,249:10:0 +X 1146 . G <*> 0 . DP=26;I16=19,7,0,0,1011,39743,0,0,1560,93600,0,0,582,13856,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,210:7:0 0,27,246:9:0 0,30,254:10:0 +X 1147 . T <*> 0 . DP=27;I16=20,6,0,0,1010,39730,0,0,1560,93600,0,0,579,13815,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,207:8:0 0,24,234:8:0 0,30,255:10:0 +X 1148 . T <*> 0 . DP=26;I16=20,6,0,0,1002,39214,0,0,1560,93600,0,0,576,13690,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,196:8:0 0,24,237:8:0 0,30,255:10:0 +X 1149 . T <*> 0 . DP=26;I16=20,6,0,0,1022,40532,0,0,1560,93600,0,0,573,13579,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,205:8:0 0,24,231:8:0 0,30,255:10:0 +X 1150 . T <*> 0 . DP=26;I16=20,6,0,0,1032,41212,0,0,1560,93600,0,0,569,13433,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,208:8:0 0,24,236:8:0 0,30,255:10:0 +X 1151 . G <*> 0 . DP=26;I16=20,6,0,0,1021,40285,0,0,1560,93600,0,0,565,13303,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,220:8:0 0,24,231:8:0 0,30,248:10:0 +X 1152 . A <*> 0 . DP=27;I16=20,7,0,0,1040,40772,0,0,1620,97200,0,0,561,13189,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,202:8:0 0,24,230:8:0 0,33,255:11:0 +X 1153 . A <*> 0 . DP=27;I16=20,7,0,0,1039,40717,0,0,1620,97200,0,0,557,13043,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,202:8:0 0,24,233:8:0 0,33,255:11:0 +X 1154 . T <*> 0 . DP=28;I16=21,7,0,0,1073,41861,0,0,1680,100800,0,0,552,12866,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,212:9:0 0,24,236:8:0 0,33,255:11:0 +X 1155 . T <*> 0 . DP=27;I16=20,7,0,0,1074,43046,0,0,1620,97200,0,0,549,12707,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,211:8:0 0,24,236:8:0 0,33,255:11:0 +X 1156 . T <*> 0 . DP=28;I16=19,8,0,0,1065,42533,0,0,1620,97200,0,0,520,11892,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,210:8:0 0,24,239:8:0 0,33,255:11:0 +X 1157 . T <*> 0 . DP=28;I16=20,8,0,0,1094,43108,0,0,1680,100800,0,0,541,12299,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,230:9:0 0,24,230:8:0 0,33,255:11:0 +X 1158 . G <*> 0 . DP=28;I16=20,8,0,0,1098,43584,0,0,1680,100800,0,0,536,12056,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,24,224:8:0 0,33,255:11:0 +X 1159 . G <*> 0 . DP=28;I16=20,8,0,0,1096,43222,0,0,1680,100800,0,0,530,11790,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,249:9:0 0,24,229:8:0 0,33,255:11:0 +X 1160 . A <*> 0 . DP=30;I16=20,10,0,0,1146,44510,0,0,1800,108000,0,0,524,11552,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,229:9:0 0,24,242:8:0 0,39,255:13:0 +X 1161 . T <*> 0 . DP=30;I16=20,10,0,0,1136,43548,0,0,1800,108000,0,0,520,11344,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,221:9:0 0,24,230:8:0 0,39,255:13:0 +X 1162 . T <*> 0 . DP=30;I16=20,10,0,0,1147,44365,0,0,1800,108000,0,0,516,11168,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,232:9:0 0,24,229:8:0 0,39,255:13:0 +X 1163 . T <*> 0 . DP=31;I16=20,11,0,0,1176,45394,0,0,1860,111600,0,0,511,10975,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,24,231:8:0 0,39,255:13:0 +X 1164 . T <*> 0 . DP=31;I16=20,11,0,0,1166,44864,0,0,1860,111600,0,0,506,10768,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,235:10:0 0,24,234:8:0 0,39,255:13:0 +X 1165 . T <*> 0 . DP=31;I16=20,11,0,0,1189,46635,0,0,1860,111600,0,0,501,10599,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,240:10:0 0,24,231:8:0 0,39,255:13:0 +X 1166 . T <*> 0 . DP=30;I16=19,11,0,0,1137,43791,0,0,1800,108000,0,0,497,10467,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,231:9:0 0,24,228:8:0 0,39,255:13:0 +X 1167 . C <*> 0 . DP=28;I16=17,11,0,0,1114,44588,0,0,1680,100800,0,0,495,10369,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,21,216:7:0 0,36,255:12:0 +X 1168 . A <*> 0 . DP=28;I16=17,11,0,0,1074,41862,0,0,1680,100800,0,0,493,10303,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,21,203:7:0 0,36,255:12:0 +X 1169 . T <*> 0 . DP=28;I16=17,11,0,0,1089,42589,0,0,1680,100800,0,0,491,10269,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,247:9:0 0,21,212:7:0 0,36,255:12:0 +X 1170 . A <*> 0 . DP=27;I16=16,11,0,0,1033,39891,0,0,1620,97200,0,0,490,10266,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,21,214:7:0 0,33,255:11:0 +X 1171 . T <*> 0 . DP=28;I16=17,11,0,0,1086,42472,0,0,1680,100800,0,0,488,10244,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,249:9:0 0,24,223:8:0 0,33,255:11:0 +X 1172 . T <*> 0 . DP=28;I16=17,11,0,0,1086,42598,0,0,1680,100800,0,0,486,10206,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,235:9:0 0,24,228:8:0 0,33,255:11:0 +X 1173 . T <*> 0 . DP=29;I16=18,11,0,0,1126,44348,0,0,1740,104400,0,0,483,10153,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,27,241:9:0 0,33,255:11:0 +X 1174 . T <*> 0 . DP=29;I16=18,11,0,0,1098,42352,0,0,1740,104400,0,0,481,10135,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,230:9:0 0,27,238:9:0 0,33,255:11:0 +X 1175 . G <*> 0 . DP=28;I16=18,10,0,0,1063,40975,0,0,1680,100800,0,0,480,10152,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,234:8:0 0,27,234:9:0 0,33,255:11:0 +X 1176 . T <*> 0 . DP=28;I16=18,10,0,0,1045,39823,0,0,1680,100800,0,0,479,10203,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,27,233:9:0 0,33,255:11:0 +X 1177 . A <*> 0 . DP=28;I16=18,10,0,0,1040,39006,0,0,1680,100800,0,0,478,10288,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,220:8:0 0,27,228:9:0 0,33,255:11:0 +X 1178 . A <*> 0 . DP=27;I16=17,10,0,0,1006,38238,0,0,1620,97200,0,0,477,10355,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,27,227:9:0 0,30,255:10:0 +X 1179 . T <*> 0 . DP=27;I16=17,10,0,0,1012,38396,0,0,1620,97200,0,0,475,10403,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,223:8:0 0,27,224:9:0 0,30,255:10:0 +X 1180 . C <*> 0 . DP=27;I16=16,10,0,0,1006,39508,0,0,1560,93600,0,0,469,10423,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,222:7:0 0,27,224:9:0 0,30,255:10:0 +X 1181 . T <*> 0 . DP=26;I16=16,10,0,0,1021,40581,0,0,1560,93600,0,0,469,10441,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,236:8:0 0,24,229:8:0 0,30,255:10:0 +X 1182 . T <*> 0 . DP=26;I16=14,11,0,0,939,35915,0,0,1500,90000,0,0,457,10347,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,236:9:0 0,21,209:7:0 0,27,255:9:0 +X 1183 . T <*> 0 . DP=25;I16=13,11,0,0,899,34555,0,0,1440,86400,0,0,455,10341,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,18,192:6:0 0,27,255:9:0 +X 1184 . G <*> 0 . DP=24;I16=13,11,0,0,916,35398,0,0,1440,86400,0,0,465,10479,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,234:8:0 0,21,201:7:0 0,27,255:9:0 +X 1185 . C <*> 0 . DP=24;I16=13,11,0,0,908,35014,0,0,1440,86400,0,0,465,10541,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,246:8:0 0,21,191:7:0 0,27,250:9:0 +X 1186 . A <*> 0 . DP=24;I16=13,11,0,0,946,37648,0,0,1440,86400,0,0,463,10525,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,240:8:0 0,21,205:7:0 0,27,255:9:0 +X 1187 . G <*> 0 . DP=25;I16=14,11,0,0,908,33870,0,0,1500,90000,0,0,461,10529,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,21,205:7:0 0,27,240:9:0 +X 1188 . T <*> 0 . DP=25;I16=14,11,0,0,886,32138,0,0,1500,90000,0,0,461,10553,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,21,196:7:0 0,24,216:8:0 +X 1189 . A <*> 0 . DP=25;I16=14,11,0,0,920,34392,0,0,1500,90000,0,0,461,10497,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,174:6:0 0,27,252:9:0 +X 1190 . T <*> 0 . DP=26;I16=14,12,0,0,960,35876,0,0,1560,93600,0,0,462,10462,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,185:6:0 0,27,252:9:0 +X 1191 . A <*> 0 . DP=26;I16=14,12,0,0,928,33922,0,0,1560,93600,0,0,464,10450,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,173:6:0 0,27,245:9:0 +X 1192 . T <*> 0 . DP=26;I16=14,12,0,0,981,37505,0,0,1560,93600,0,0,465,10413,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,191:6:0 0,27,255:9:0 +X 1193 . T <*> 0 . DP=26;I16=14,12,0,0,976,37054,0,0,1560,93600,0,0,466,10402,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,191:6:0 0,27,255:9:0 +X 1194 . T <*> 0 . DP=26;I16=14,12,0,0,951,35219,0,0,1560,93600,0,0,466,10368,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,178:6:0 0,27,249:9:0 +X 1195 . A <*> 0 . DP=26;I16=14,12,0,0,917,33253,0,0,1560,93600,0,0,466,10362,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,177:6:0 0,27,235:9:0 +X 1196 . C <*> 0 . DP=25;I16=13,12,0,0,921,34209,0,0,1500,90000,0,0,466,10334,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,187:6:0 0,27,236:9:0 +X 1197 . C <*> 0 . DP=24;I16=12,12,0,0,906,34862,0,0,1440,86400,0,0,464,10184,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,186:6:0 0,24,233:8:0 +X 1198 . A <*> 0 . DP=24;I16=12,12,0,0,937,36815,0,0,1440,86400,0,0,461,10013,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,190:6:0 0,24,245:8:0 +X 1199 . G <*> 0 . DP=24;I16=12,12,0,0,879,33035,0,0,1440,86400,0,0,457,9821,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,163:6:0 0,24,221:8:0 +X 1200 . T <*> 0 . DP=24;I16=11,12,0,0,895,35141,0,0,1380,82800,0,0,428,9032,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,176:5:0 0,24,247:8:0 +X 1201 . T <*> 0 . DP=24;I16=12,12,0,0,889,33727,0,0,1440,86400,0,0,449,9521,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,177:6:0 0,24,238:8:0 +X 1202 . C <*> 0 . DP=25;I16=13,12,0,0,929,35121,0,0,1500,90000,0,0,445,9413,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,175:6:0 0,24,230:8:0 +X 1203 . A <*> 0 . DP=25;I16=13,12,0,0,943,36107,0,0,1500,90000,0,0,442,9334,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,184:6:0 0,24,241:8:0 +X 1204 . G <*> 0 . DP=24;I16=13,11,0,0,876,33106,0,0,1440,86400,0,0,439,9235,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,174:6:0 0,21,218:7:0 +X 1205 . C <*> 0 . DP=24;I16=13,11,0,0,891,33869,0,0,1440,86400,0,0,436,9166,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,176:6:0 0,21,217:7:0 +X 1206 . A <*> 0 . DP=23;I16=13,10,0,0,846,31744,0,0,1380,82800,0,0,434,9126,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,179:6:0 0,21,212:7:0 +X 1207 . T <*> 0 . DP=23;I16=13,9,0,0,819,30877,0,0,1320,79200,0,0,407,8489,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,254:10:0 0,18,189:6:0 0,18,194:6:0 +X 1208 . C <*> 0 . DP=24;I16=14,10,0,0,910,35236,0,0,1440,86400,0,0,429,9079,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,190:7:0 0,21,217:7:0 +X 1209 . C T,<*> 0 . DP=24;I16=14,9,0,1,869,33481,21,441,1380,82800,60,3600,408,8710,19,361;QS=2.91393,0.0860656,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,30,255,30,255,255:10:0 0,0,153,18,156,166:7:1 0,21,209,21,209,209:7:0 +X 1210 . C <*> 0 . DP=24;I16=14,10,0,0,915,35713,0,0,1440,86400,0,0,425,9091,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,199:7:0 0,21,209:7:0 +X 1211 . T <*> 0 . DP=24;I16=14,10,0,0,905,34669,0,0,1440,86400,0,0,423,9139,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,213:7:0 0,21,214:7:0 +X 1212 . A <*> 0 . DP=24;I16=14,10,0,0,850,30690,0,0,1440,86400,0,0,421,9215,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,246:10:0 0,21,190:7:0 0,21,204:7:0 +X 1213 . A <*> 0 . DP=24;I16=14,10,0,0,852,31192,0,0,1440,86400,0,0,418,9268,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,21,197:7:0 0,21,195:7:0 +X 1214 . C <*> 0 . DP=23;I16=13,10,0,0,851,32099,0,0,1380,82800,0,0,415,9295,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,186:7:0 0,18,184:6:0 +X 1215 . T <*> 0 . DP=23;I16=13,9,0,0,839,32475,0,0,1320,79200,0,0,386,8668,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,211:7:0 0,15,172:5:0 +X 1216 . C <*> 0 . DP=23;I16=13,10,0,0,863,32923,0,0,1380,82800,0,0,406,9260,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,196:7:0 0,18,172:6:0 +X 1217 . A <*> 0 . DP=22;I16=12,10,0,0,820,30926,0,0,1320,79200,0,0,402,9244,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,172:6:0 0,18,191:6:0 +X 1218 . A <*> 0 . DP=22;I16=12,10,0,0,764,27286,0,0,1320,79200,0,0,398,9244,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,145:6:0 0,18,184:6:0 +X 1219 . A <*> 0 . DP=21;I16=12,9,0,0,803,31119,0,0,1260,75600,0,0,395,9259,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,175:6:0 0,15,173:5:0 +X 1220 . A <*> 0 . DP=21;I16=12,9,0,0,752,27700,0,0,1260,75600,0,0,392,9288,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,18,167:6:0 0,15,167:5:0 +X 1221 . A <*> 0 . DP=20;I16=12,8,0,0,722,26564,0,0,1200,72000,0,0,390,9330,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,147:5:0 0,15,157:5:0 +X 1222 . T <*> 0 . DP=18;I16=10,8,0,0,666,25034,0,0,1080,64800,0,0,389,9333,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,245:9:0 0,15,143:5:0 0,12,142:4:0 +X 1223 . T <*> 0 . DP=17;I16=9,7,0,0,574,21262,0,0,960,57600,0,0,364,8720,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,232:9:0 0,12,122:4:0 0,9,120:3:0 +X 1224 . C <*> 0 . DP=19;I16=10,7,0,0,639,24429,0,0,1020,61200,0,0,364,8740,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,128:4:0 0,9,112:3:0 +X 1225 . A <*> 0 . DP=19;I16=10,9,0,0,713,27139,0,0,1109,65641,0,0,395,9419,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,137:5:0 0,12,145:4:0 +X 1226 . A <*> 0 . DP=19;I16=10,9,0,0,688,25468,0,0,1109,65641,0,0,397,9469,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,127:5:0 0,12,147:4:0 +X 1227 . A <*> 0 . DP=19;I16=10,9,0,0,698,26104,0,0,1109,65641,0,0,399,9531,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,133:5:0 0,12,146:4:0 +X 1228 . A <*> 0 . DP=19;I16=10,9,0,0,705,26721,0,0,1109,65641,0,0,399,9505,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,143:5:0 0,12,145:4:0 +X 1229 . A <*> 0 . DP=18;I16=10,8,0,0,693,26891,0,0,1049,62041,0,0,400,9490,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,123:4:0 0,12,138:4:0 +X 1230 . T <*> 0 . DP=18;I16=10,8,0,0,643,23601,0,0,1049,62041,0,0,401,9485,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,30,245:10:0 0,12,115:4:0 0,12,144:4:0 +X 1231 . C <*> 0 . DP=18;I16=10,7,0,0,663,26041,0,0,1020,61200,0,0,390,9320,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,98:3:0 0,12,138:4:0 +X 1232 . T <*> 0 . DP=18;I16=10,8,0,0,683,26261,0,0,1049,62041,0,0,401,9409,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,133:4:0 0,12,129:4:0 +X 1233 . G <*> 0 . DP=18;I16=10,8,0,0,657,24509,0,0,1049,62041,0,0,401,9389,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,124:4:0 0,12,129:4:0 +X 1234 . A <*> 0 . DP=19;I16=10,8,0,0,677,26177,0,0,1080,64800,0,0,386,9134,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,101:3:0 0,12,144:4:0 +X 1235 . A <*> 0 . DP=19;I16=10,9,0,0,697,26363,0,0,1109,65641,0,0,400,9282,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,129:4:0 0,12,140:4:0 +X 1236 . A <*> 0 . DP=19;I16=10,9,0,0,671,24693,0,0,1109,65641,0,0,398,9148,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,103:4:0 0,12,136:4:0 +X 1237 . T <*> 0 . DP=19;I16=9,9,0,0,649,24061,0,0,1049,62041,0,0,370,8356,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,98:3:0 0,12,135:4:0 +X 1238 . C <*> 0 . DP=20;I16=11,9,0,0,733,27709,0,0,1169,69241,0,0,391,8783,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,104:4:0 0,12,145:4:0 +X 1239 . C <*> 0 . DP=20;I16=10,9,0,0,672,24596,0,0,1109,65641,0,0,363,7981,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,76:3:0 0,12,124:4:0 +X 1240 . C <*> 0 . DP=20;I16=11,9,0,0,723,26895,0,0,1169,69241,0,0,385,8451,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,118:4:0 0,12,129:4:0 +X 1241 . A <*> 0 . DP=20;I16=11,9,0,0,719,26575,0,0,1169,69241,0,0,382,8318,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,104:4:0 0,12,141:4:0 +X 1242 . A <*> 0 . DP=21;I16=12,9,0,0,749,27599,0,0,1229,72841,0,0,379,8207,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,109:4:0 0,15,153:5:0 +X 1243 . A <*> 0 . DP=21;I16=12,9,0,0,738,26862,0,0,1229,72841,0,0,377,8119,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,110:4:0 0,15,158:5:0 +X 1244 . C <*> 0 . DP=21;I16=12,8,0,0,670,22952,0,0,1169,69241,0,0,365,7955,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,101:4:0 0,15,148:5:0 +X 1245 . G <*> 0 . DP=21;I16=12,9,0,0,657,21627,0,0,1229,72841,0,0,373,8015,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,245:12:0 0,12,95:4:0 0,15,158:5:0 +X 1246 . C <*> 0 . DP=21;I16=12,9,0,0,652,21348,0,0,1229,72841,0,0,370,7948,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,252:12:0 0,12,95:4:0 0,15,146:5:0 +X 1247 . G <*> 0 . DP=20;I16=11,9,0,0,655,22291,0,0,1169,69241,0,0,367,7853,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,87:4:0 0,15,150:5:0 +X 1248 . C <*> 0 . DP=20;I16=10,8,0,0,659,25037,0,0,1080,64800,0,0,314,6530,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,90:3:0 0,15,156:5:0 +X 1249 . C <*> 0 . DP=21;I16=12,9,0,0,772,28954,0,0,1229,72841,0,0,360,7680,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,111:4:0 0,15,166:5:0 +X 1250 . A <*> 0 . DP=21;I16=12,9,0,0,757,27599,0,0,1229,72841,0,0,356,7554,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,114:4:0 0,15,161:5:0 +X 1251 . A <*> 0 . DP=21;I16=12,9,0,0,758,27890,0,0,1229,72841,0,0,352,7452,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,115:4:0 0,15,174:5:0 +X 1252 . T <*> 0 . DP=21;I16=12,9,0,0,758,27574,0,0,1229,72841,0,0,348,7374,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,124:4:0 0,15,159:5:0 +X 1253 . A <*> 0 . DP=20;I16=12,8,0,0,718,26292,0,0,1169,69241,0,0,345,7319,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,127:4:0 0,12,144:4:0 +X 1254 . A <*> 0 . DP=20;I16=12,8,0,0,781,30817,0,0,1169,69241,0,0,342,7286,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,134:4:0 0,12,156:4:0 +X 1255 . G <*> 0 . DP=21;I16=12,9,0,0,785,30039,0,0,1229,72841,0,0,339,7275,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,128:4:0 0,15,169:5:0 +X 1256 . C <*> 0 . DP=20;I16=12,8,0,0,742,27910,0,0,1169,69241,0,0,338,7286,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,116:4:0 0,15,165:5:0 +X 1257 . A <*> 0 . DP=20;I16=12,8,0,0,745,28017,0,0,1169,69241,0,0,337,7319,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,132:4:0 0,15,167:5:0 +X 1258 . T <*> 0 . DP=20;I16=12,8,0,0,753,28507,0,0,1169,69241,0,0,336,7374,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,126:4:0 0,15,170:5:0 +X 1259 . T <*> 0 . DP=20;I16=12,8,0,0,690,24762,0,0,1169,69241,0,0,335,7451,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,236:11:0 0,12,128:4:0 0,15,170:5:0 +X 1260 . C <*> 0 . DP=20;I16=12,8,0,0,719,26541,0,0,1169,69241,0,0,333,7499,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,127:4:0 0,15,155:5:0 +X 1261 . C <*> 0 . DP=18;I16=11,6,0,0,602,22374,0,0,989,58441,0,0,308,6940,0,0;QS=3,0;MQSB=0.85832;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,117:4:0 0,9,109:3:0 +X 1262 . C <*> 0 . DP=18;I16=12,6,0,0,653,24345,0,0,1049,62041,0,0,333,7597,0,0;QS=3,0;MQSB=0.85394;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,15,145:5:0 0,9,114:3:0 +X 1263 . T <*> 0 . DP=17;I16=12,5,0,0,654,25656,0,0,989,58441,0,0,335,7645,0,0;QS=3,0;MQSB=0.818731;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,15,158:5:0 0,9,118:3:0 +X 1264 . T <*> 0 . DP=17;I16=12,5,0,0,615,22855,0,0,989,58441,0,0,336,7658,0,0;QS=3,0;MQSB=0.818731;MQ0F=0 PL:DP:DV 0,27,226:9:0 0,15,149:5:0 0,9,114:3:0 +X 1265 . T <*> 0 . DP=17;I16=12,5,0,0,620,23176,0,0,989,58441,0,0,334,7538,0,0;QS=3,0;MQSB=0.818731;MQ0F=0 PL:DP:DV 0,27,232:9:0 0,15,144:5:0 0,9,114:3:0 +X 1266 . G <*> 0 . DP=18;I16=13,5,0,0,675,25765,0,0,1049,62041,0,0,332,7438,0,0;QS=3,0;MQSB=0.814433;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,145:5:0 0,9,114:3:0 +X 1267 . A <*> 0 . DP=18;I16=13,5,0,0,663,24799,0,0,1049,62041,0,0,331,7359,0,0;QS=3,0;MQSB=0.814433;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,15,138:5:0 0,9,114:3:0 +X 1268 . G <*> 0 . DP=18;I16=13,5,0,0,638,23584,0,0,1049,62041,0,0,329,7251,0,0;QS=3,0;MQSB=0.814433;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,112:5:0 0,9,108:3:0 +X 1269 . C <*> 0 . DP=18;I16=13,5,0,0,592,20458,0,0,1049,62041,0,0,327,7163,0,0;QS=3,0;MQSB=0.814433;MQ0F=0 PL:DP:DV 0,30,224:10:0 0,15,130:5:0 0,9,107:3:0 +X 1270 . G <*> 0 . DP=18;I16=13,5,0,0,537,16775,0,0,1049,62041,0,0,325,7095,0,0;QS=3,0;MQSB=0.814433;MQ0F=0 PL:DP:DV 0,30,206:10:0 0,15,104:5:0 0,9,98:3:0 +X 1271 . T <*> 0 . DP=18;I16=12,5,0,0,620,22824,0,0,989,58441,0,0,298,6422,0,0;QS=3,0;MQSB=0.818731;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,15,138:5:0 0,9,109:3:0 +X 1272 . C <*> 0 . DP=17;I16=11,5,0,0,597,22587,0,0,929,54841,0,0,297,6393,0,0;QS=3,0;MQSB=0.823561;MQ0F=0 PL:DP:DV 0,27,251:9:0 0,12,113:4:0 0,9,110:3:0 +X 1273 . A <*> 0 . DP=18;I16=12,6,0,0,633,23063,0,0,1049,62041,0,0,318,6866,0,0;QS=3,0;MQSB=0.85394;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,109:4:0 0,9,113:3:0 +X 1274 . T <*> 0 . DP=17;I16=10,6,0,0,609,23335,0,0,929,54841,0,0,293,6205,0,0;QS=3,0;MQSB=0.863243;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,67:2:0 0,9,115:3:0 +X 1275 . G <*> 0 . DP=17;I16=11,6,0,0,602,21976,0,0,989,58441,0,0,317,6763,0,0;QS=3,0;MQSB=0.85832;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,87:3:0 0,9,112:3:0 +X 1276 . T <*> 0 . DP=17;I16=11,6,0,0,587,20925,0,0,989,58441,0,0,316,6714,0,0;QS=3,0;MQSB=0.85832;MQ0F=0 PL:DP:DV 0,33,248:11:0 0,9,94:3:0 0,9,110:3:0 +X 1277 . C <*> 0 . DP=18;I16=11,7,0,0,590,20126,0,0,1049,62041,0,0,314,6634,0,0;QS=3,0;MQSB=0.883327;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,85:3:0 0,9,106:3:0 +X 1278 . G <*> 0 . DP=18;I16=11,7,0,0,603,20675,0,0,1049,62041,0,0,313,6575,0,0;QS=3,0;MQSB=0.883327;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,77:3:0 0,9,96:3:0 +X 1279 . G <*> 0 . DP=18;I16=11,7,0,0,646,23662,0,0,1049,62041,0,0,312,6538,0,0;QS=3,0;MQSB=0.883327;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,85:3:0 0,9,113:3:0 +X 1280 . T <*> 0 . DP=18;I16=10,7,0,0,558,19192,0,0,989,58441,0,0,296,6298,0,0;QS=3,0;MQSB=0.887766;MQ0F=0 PL:DP:DV 0,33,249:11:0 0,9,86:3:0 0,9,97:3:0 +X 1281 . G <*> 0 . DP=17;I16=10,6,0,0,564,21244,0,0,929,54841,0,0,270,5658,0,0;QS=3,0;MQSB=0.863243;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,85:3:0 0,9,103:3:0 +X 1282 . C <*> 0 . DP=18;I16=10,8,0,0,654,24308,0,0,1049,62041,0,0,294,6286,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,94:3:0 0,12,131:4:0 +X 1283 . T <*> 0 . DP=18;I16=10,8,0,0,677,26313,0,0,1049,62041,0,0,294,6308,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,83:3:0 0,12,154:4:0 +X 1284 . T <*> 0 . DP=18;I16=10,8,0,0,631,22949,0,0,1049,62041,0,0,293,6301,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,9,92:3:0 0,12,145:4:0 +X 1285 . G <*> 0 . DP=18;I16=10,7,0,0,657,25545,0,0,989,58441,0,0,267,5691,0,0;QS=3,0;MQSB=0.887766;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,94:3:0 0,12,145:4:0 +X 1286 . G <*> 0 . DP=18;I16=10,8,0,0,650,24684,0,0,1049,62041,0,0,291,6353,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,78:3:0 0,12,148:4:0 +X 1287 . A <*> 0 . DP=17;I16=9,8,0,0,609,22229,0,0,989,58441,0,0,291,6411,0,0;QS=3,0;MQSB=0.91051;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,91:3:0 0,12,137:4:0 +X 1288 . A <*> 0 . DP=17;I16=9,8,0,0,605,22315,0,0,989,58441,0,0,290,6438,0,0;QS=3,0;MQSB=0.91051;MQ0F=0 PL:DP:DV 0,30,245:10:0 0,9,103:3:0 0,12,140:4:0 +X 1289 . T <*> 0 . DP=18;I16=10,8,0,0,637,23207,0,0,1049,62041,0,0,289,6483,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,99:3:0 0,12,141:4:0 +X 1290 . G <*> 0 . DP=15;I16=9,6,0,0,559,21163,0,0,869,51241,0,0,292,6544,0,0;QS=3,0;MQSB=0.868815;MQ0F=0 PL:DP:DV 0,27,242:9:0 0,9,97:3:0 0,9,106:3:0 +X 1291 . T <*> 0 . DP=15;I16=9,6,0,0,547,20303,0,0,869,51241,0,0,295,6619,0,0;QS=3,0;MQSB=0.868815;MQ0F=0 PL:DP:DV 0,27,225:9:0 0,9,91:3:0 0,9,117:3:0 +X 1292 . T <*> 0 . DP=15;I16=9,6,0,0,559,21121,0,0,869,51241,0,0,297,6657,0,0;QS=3,0;MQSB=0.868815;MQ0F=0 PL:DP:DV 0,27,236:9:0 0,9,95:3:0 0,9,113:3:0 +X 1293 . T <*> 0 . DP=15;I16=9,6,0,0,578,22428,0,0,869,51241,0,0,299,6707,0,0;QS=3,0;MQSB=0.868815;MQ0F=0 PL:DP:DV 0,27,242:9:0 0,9,100:3:0 0,9,116:3:0 +X 1294 . G <*> 0 . DP=16;I16=9,7,0,0,606,23572,0,0,929,54841,0,0,301,6769,0,0;QS=3,0;MQSB=0.892753;MQ0F=0 PL:DP:DV 0,27,254:9:0 0,12,110:4:0 0,9,119:3:0 +X 1295 . G <*> 0 . DP=16;I16=9,7,0,0,567,21419,0,0,929,54841,0,0,304,6844,0,0;QS=3,0;MQSB=0.892753;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,12,102:4:0 0,9,114:3:0 +X 1296 . G <*> 0 . DP=16;I16=8,7,0,0,518,19300,0,0,869,51241,0,0,294,6740,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,9,89:3:0 0,9,114:3:0 +X 1297 . G <*> 0 . DP=18;I16=9,8,0,0,551,19323,0,0,958,55682,0,0,322,7444,0,0;QS=3,0;MQSB=0.998843;MQ0F=0 PL:DP:DV 0,30,219:10:0 0,9,86:3:0 0,12,133:4:0 +X 1298 . T <*> 0 . DP=18;I16=10,8,0,0,615,22371,0,0,1018,59282,0,0,336,7638,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,30,233:10:0 0,12,105:4:0 0,12,138:4:0 +X 1299 . T <*> 0 . DP=18;I16=9,8,0,0,619,23135,0,0,958,55682,0,0,328,7548,0,0;QS=3,0;MQSB=0.998843;MQ0F=0 PL:DP:DV 0,30,242:10:0 0,9,97:3:0 0,12,136:4:0 +X 1300 . T <*> 0 . DP=18;I16=10,8,0,0,631,23107,0,0,1018,59282,0,0,338,7638,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,30,235:10:0 0,12,121:4:0 0,12,136:4:0 +X 1301 . T G,<*> 0 . DP=18;I16=8,8,1,0,599,22623,18,324,929,54841,29,841,314,7040,25,625;QS=2.9434,0.0566038,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.998843;BQB=1;MQ0F=0 PL:DP:DV 0,9,213,24,216,222:9:1 0,12,126,12,126,126:4:0 0,12,135,12,135,135:4:0 +X 1302 . G <*> 0 . DP=17;I16=9,8,0,0,624,23544,0,0,958,55682,0,0,341,7709,0,0;QS=3,0;MQSB=0.998843;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,12,127:4:0 0,12,140:4:0 +X 1303 . G <*> 0 . DP=17;I16=9,8,0,0,582,21200,0,0,958,55682,0,0,342,7718,0,0;QS=3,0;MQSB=0.998843;MQ0F=0 PL:DP:DV 0,27,217:9:0 0,12,125:4:0 0,12,138:4:0 +X 1304 . A <*> 0 . DP=18;I16=10,8,0,0,652,24124,0,0,1018,59282,0,0,343,7741,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,27,218:9:0 0,12,131:4:0 0,15,169:5:0 +X 1305 . T <*> 0 . DP=18;I16=10,8,0,0,685,26381,0,0,1018,59282,0,0,345,7779,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,12,122:4:0 0,15,174:5:0 +X 1306 . T <*> 0 . DP=18;I16=9,8,0,0,644,24628,0,0,958,55682,0,0,345,7829,0,0;QS=3,0;MQSB=0.998843;MQ0F=0 PL:DP:DV 0,27,236:9:0 0,9,106:3:0 0,15,168:5:0 +X 1307 . T <*> 0 . DP=17;I16=9,8,0,0,628,23746,0,0,958,55682,0,0,348,7902,0,0;QS=3,0;MQSB=0.998843;MQ0F=0 PL:DP:DV 0,27,226:9:0 0,9,104:3:0 0,15,167:5:0 +X 1308 . A <*> 0 . DP=19;I16=9,10,0,0,690,25500,0,0,1078,62882,0,0,350,7938,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,30,236:10:0 0,12,127:4:0 0,15,173:5:0 +X 1309 . C <*> 0 . DP=19;I16=9,9,0,0,698,27148,0,0,1049,62041,0,0,342,7818,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,106:3:0 0,15,169:5:0 +X 1310 . A <*> 0 . DP=19;I16=9,10,0,0,751,29953,0,0,1078,62882,0,0,356,7958,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,132:4:0 0,15,183:5:0 +X 1311 . G <*> 0 . DP=19;I16=9,10,0,0,742,29384,0,0,1078,62882,0,0,359,7995,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,128:4:0 0,15,174:5:0 +X 1312 . C <*> 0 . DP=19;I16=9,10,0,0,717,27783,0,0,1078,62882,0,0,362,8050,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,115:4:0 0,15,166:5:0 +X 1313 . T <*> 0 . DP=19;I16=9,10,0,0,751,30061,0,0,1078,62882,0,0,364,8074,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,135:4:0 0,15,175:5:0 +X 1314 . T <*> 0 . DP=19;I16=9,10,0,0,707,26983,0,0,1078,62882,0,0,366,8118,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,30,245:10:0 0,12,134:4:0 0,15,174:5:0 +X 1315 . T <*> 0 . DP=19;I16=9,10,0,0,717,27491,0,0,1078,62882,0,0,367,8131,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,12,132:4:0 0,15,174:5:0 +X 1316 . G <*> 0 . DP=21;I16=10,11,0,0,776,29502,0,0,1198,70082,0,0,368,8162,0,0;QS=3,0;MQSB=0.99938;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,128:4:0 0,18,188:6:0 +X 1317 . G <*> 0 . DP=21;I16=10,11,0,0,751,27855,0,0,1198,70082,0,0,371,8213,0,0;QS=3,0;MQSB=0.99938;MQ0F=0 PL:DP:DV 0,33,253:11:0 0,12,130:4:0 0,18,179:6:0 +X 1318 . G <*> 0 . DP=21;I16=10,11,0,0,749,27663,0,0,1198,70082,0,0,372,8188,0,0;QS=3,0;MQSB=0.99938;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,130:4:0 0,18,184:6:0 +X 1319 . A <*> 0 . DP=21;I16=10,11,0,0,768,28390,0,0,1198,70082,0,0,373,8189,0,0;QS=3,0;MQSB=0.99938;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,124:4:0 0,18,186:6:0 +X 1320 . C <*> 0 . DP=21;I16=10,11,0,0,728,25496,0,0,1198,70082,0,0,373,8165,0,0;QS=3,0;MQSB=0.99938;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,113:4:0 0,18,161:6:0 +X 1321 . G <*> 0 . DP=22;I16=10,12,0,0,762,27412,0,0,1289,76441,0,0,374,8164,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,33,244:11:0 0,9,104:3:0 0,24,208:8:0 +X 1322 . C <*> 0 . DP=22;I16=10,12,0,0,852,33528,0,0,1289,76441,0,0,377,8187,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,111:3:0 0,24,225:8:0 +X 1323 . T <*> 0 . DP=22;I16=10,12,0,0,874,35152,0,0,1289,76441,0,0,379,8185,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,112:3:0 0,24,237:8:0 +X 1324 . C <*> 0 . DP=21;I16=9,12,0,0,793,30585,0,0,1229,72841,0,0,381,8157,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,109:3:0 0,24,218:8:0 +X 1325 . A <*> 0 . DP=21;I16=9,12,0,0,782,29430,0,0,1229,72841,0,0,383,8153,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,105:3:0 0,24,218:8:0 +X 1326 . A <*> 0 . DP=21;I16=9,12,0,0,791,30479,0,0,1229,72841,0,0,385,8173,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,9,108:3:0 0,24,230:8:0 +X 1327 . C <*> 0 . DP=23;I16=11,12,0,0,834,31048,0,0,1349,80041,0,0,387,8217,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,99:3:0 0,27,237:9:0 +X 1328 . C <*> 0 . DP=23;I16=11,12,0,0,878,33972,0,0,1349,80041,0,0,391,8287,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,105:3:0 0,27,254:9:0 +X 1329 . T <*> 0 . DP=23;I16=11,12,0,0,882,34756,0,0,1349,80041,0,0,395,8385,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,112:3:0 0,27,255:9:0 +X 1330 . G <*> 0 . DP=23;I16=11,12,0,0,856,32638,0,0,1349,80041,0,0,398,8460,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,101:3:0 0,27,241:9:0 +X 1331 . T <*> 0 . DP=23;I16=11,12,0,0,847,31785,0,0,1349,80041,0,0,400,8512,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,106:3:0 0,27,247:9:0 +X 1332 . A <*> 0 . DP=23;I16=11,12,0,0,826,30264,0,0,1349,80041,0,0,402,8592,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,252:11:0 0,9,104:3:0 0,27,238:9:0 +X 1333 . C <*> 0 . DP=23;I16=11,12,0,0,836,30928,0,0,1349,80041,0,0,404,8700,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,101:3:0 0,27,236:9:0 +X 1334 . C <*> 0 . DP=22;I16=11,11,0,0,830,32380,0,0,1289,76441,0,0,405,8733,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,107:3:0 0,27,238:9:0 +X 1335 . T <*> 0 . DP=22;I16=11,11,0,0,877,35371,0,0,1289,76441,0,0,406,8788,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,113:3:0 0,27,253:9:0 +X 1336 . C <*> 0 . DP=25;I16=12,12,0,0,890,33648,0,0,1378,80882,0,0,398,8784,0,0;QS=3,0;MQSB=0.786628;MQ0F=0 PL:DP:DV 0,33,250:11:0 0,12,131:4:0 0,27,237:9:0 +X 1337 . A <*> 0 . DP=26;I16=13,13,0,0,941,34611,0,0,1498,88082,0,0,411,8967,0,0;QS=3,0;MQSB=0.800737;MQ0F=0 PL:DP:DV 0,33,249:11:0 0,15,152:5:0 0,30,247:10:0 +X 1338 . A <*> 0 . DP=26;I16=12,14,0,0,982,37358,0,0,1498,88082,0,0,416,9048,0,0;QS=3,0;MQSB=0.771623;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,153:5:0 0,30,255:10:0 +X 1339 . T <*> 0 . DP=27;I16=12,15,0,0,989,36855,0,0,1558,91682,0,0,422,9160,0,0;QS=3,0;MQSB=0.765017;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,151:5:0 0,33,255:11:0 +X 1340 . A <*> 0 . DP=27;I16=11,15,0,0,937,34141,0,0,1498,88082,0,0,425,9289,0,0;QS=3,0;MQSB=0.738577;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,15,149:5:0 0,33,254:11:0 +X 1341 . A <*> 0 . DP=27;I16=12,14,0,0,929,33961,0,0,1498,88082,0,0,410,8810,0,0;QS=3,0;MQSB=0.771623;MQ0F=0 PL:DP:DV 0,30,245:10:0 0,15,141:5:0 0,33,255:11:0 +X 1342 . A <*> 0 . DP=27;I16=12,15,0,0,951,34575,0,0,1558,91682,0,0,439,9499,0,0;QS=3,0;MQSB=0.765017;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,15,159:5:0 0,33,249:11:0 +X 1343 . C <*> 0 . DP=25;I16=10,15,0,0,902,33364,0,0,1469,87241,0,0,445,9593,0,0;QS=3,0;MQSB=0.9171;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,140:5:0 0,30,233:10:0 +X 1344 . C <*> 0 . DP=26;I16=10,16,0,0,985,37915,0,0,1529,90841,0,0,451,9715,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,163:6:0 0,30,238:10:0 +X 1345 . T <*> 0 . DP=26;I16=10,16,0,0,1004,39262,0,0,1529,90841,0,0,458,9866,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,182:6:0 0,30,242:10:0 +X 1346 . G <*> 0 . DP=26;I16=10,16,0,0,1003,38983,0,0,1529,90841,0,0,465,10047,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,172:6:0 0,30,239:10:0 +X 1347 . A <*> 0 . DP=26;I16=10,16,0,0,995,38409,0,0,1529,90841,0,0,470,10156,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,177:6:0 0,30,243:10:0 +X 1348 . T <*> 0 . DP=26;I16=10,16,0,0,988,38126,0,0,1529,90841,0,0,474,10242,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,18,185:6:0 0,30,251:10:0 +X 1349 . T <*> 0 . DP=26;I16=9,15,0,0,905,34409,0,0,1409,83641,0,0,454,9730,0,0;QS=3,0;MQSB=0.904837;MQ0F=0 PL:DP:DV 0,24,225:8:0 0,18,176:6:0 0,30,248:10:0 +X 1350 . T <*> 0 . DP=26;I16=10,16,0,0,975,36909,0,0,1498,88082,0,0,485,10495,0,0;QS=3,0;MQSB=0.700784;MQ0F=0 PL:DP:DV 0,27,242:9:0 0,21,195:7:0 0,30,249:10:0 +X 1351 . T <*> 0 . DP=26;I16=10,16,0,0,956,35602,0,0,1498,88082,0,0,491,10663,0,0;QS=3,0;MQSB=0.700784;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,21,193:7:0 0,30,240:10:0 +X 1352 . A <*> 0 . DP=26;I16=10,16,0,0,901,31965,0,0,1498,88082,0,0,496,10810,0,0;QS=3,0;MQSB=0.700784;MQ0F=0 PL:DP:DV 0,27,250:9:0 0,21,180:7:0 0,30,211:10:0 +X 1353 . A <*> 0 . DP=26;I16=10,16,0,0,927,33583,0,0,1498,88082,0,0,499,10885,0,0;QS=3,0;MQSB=0.700784;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,21,187:7:0 0,30,224:10:0 +X 1354 . A <*> 0 . DP=26;I16=10,16,0,0,927,33621,0,0,1498,88082,0,0,502,10986,0,0;QS=3,0;MQSB=0.700784;MQ0F=0 PL:DP:DV 0,27,237:9:0 0,21,190:7:0 0,30,223:10:0 +X 1355 . A <*> 0 . DP=26;I16=10,16,0,0,924,33736,0,0,1498,88082,0,0,505,11113,0,0;QS=3,0;MQSB=0.700784;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,21,186:7:0 0,30,227:10:0 +X 1356 . A <*> 0 . DP=25;I16=10,15,0,0,916,34050,0,0,1438,84482,0,0,509,11265,0,0;QS=3,0;MQSB=0.707404;MQ0F=0 PL:DP:DV 0,27,249:9:0 0,21,178:7:0 0,27,226:9:0 +X 1357 . A <*> 0 . DP=25;I16=9,15,0,0,949,38007,0,0,1378,80882,0,0,488,10816,0,0;QS=3,0;MQSB=0.67032;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,21,193:7:0 0,24,217:8:0 +X 1358 . G <*> 0 . DP=25;I16=9,15,0,0,873,32435,0,0,1378,80882,0,0,491,10967,0,0;QS=3,0;MQSB=0.67032;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,21,172:7:0 0,24,188:8:0 +X 1359 . T <*> 0 . DP=25;I16=9,15,0,0,857,31139,0,0,1378,80882,0,0,494,11144,0,0;QS=3,0;MQSB=0.67032;MQ0F=0 PL:DP:DV 0,27,232:9:0 0,21,184:7:0 0,24,196:8:0 +X 1360 . T <*> 0 . DP=25;I16=9,15,0,0,879,32419,0,0,1378,80882,0,0,497,11347,0,0;QS=3,0;MQSB=0.67032;MQ0F=0 PL:DP:DV 0,27,248:9:0 0,21,184:7:0 0,24,192:8:0 +X 1361 . T <*> 0 . DP=27;I16=9,17,0,0,936,34238,0,0,1498,88082,0,0,500,11576,0,0;QS=3,0;MQSB=0.657209;MQ0F=0 PL:DP:DV 0,27,234:9:0 0,24,201:8:0 0,27,206:9:0 +X 1362 . G <*> 0 . DP=26;I16=9,17,0,0,973,36785,0,0,1498,88082,0,0,502,11680,0,0;QS=3,0;MQSB=0.657209;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,24,202:8:0 0,27,207:9:0 +X 1363 . G <*> 0 . DP=25;I16=8,17,0,0,936,35390,0,0,1438,84482,0,0,504,11756,0,0;QS=3,0;MQSB=0.612391;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,21,181:7:0 0,27,202:9:0 +X 1364 . G <*> 0 . DP=25;I16=8,17,0,0,902,32840,0,0,1438,84482,0,0,504,11752,0,0;QS=3,0;MQSB=0.612391;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,21,184:7:0 0,27,200:9:0 +X 1365 . G <*> 0 . DP=26;I16=9,17,0,0,946,35224,0,0,1498,88082,0,0,503,11717,0,0;QS=3,0;MQSB=0.657209;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,24,190:8:0 0,27,202:9:0 +X 1366 . G <*> 0 . DP=25;I16=8,15,0,0,840,31058,0,0,1318,77282,0,0,454,10450,0,0;QS=3,0;MQSB=0.625784;MQ0F=0 PL:DP:DV 0,21,215:7:0 0,21,181:7:0 0,27,199:9:0 +X 1367 . G C,<*> 0 . DP=25;I16=7,16,0,1,836,30888,27,729,1349,80041,60,3600,472,11152,15,225;QS=2.91641,0.0835913,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.864405;BQB=1;MQ0F=0 PL:DP:DV 0,24,236,24,236,236:8:0 0,21,179,21,179,179:7:0 0,0,171,24,174,189:9:1 +X 1368 . A <*> 0 . DP=26;I16=8,17,0,0,869,30839,0,0,1438,84482,0,0,481,11095,0,0;QS=3,0;MQSB=0.612391;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,21,180:7:0 0,27,197:9:0 +X 1369 . T <*> 0 . DP=26;I16=8,18,0,0,902,32160,0,0,1498,88082,0,0,508,11758,0,0;QS=3,0;MQSB=0.606531;MQ0F=0 PL:DP:DV 0,27,242:9:0 0,24,197:8:0 0,27,194:9:0 +X 1370 . T <*> 0 . DP=27;I16=8,17,0,0,926,34736,0,0,1438,84482,0,0,458,10466,0,0;QS=3,0;MQSB=0.612391;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,21,195:7:0 0,27,215:9:0 +X 1371 . C <*> 0 . DP=27;I16=8,19,0,0,929,33255,0,0,1558,91682,0,0,509,11695,0,0;QS=3,0;MQSB=0.601139;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,24,196:8:0 0,30,196:10:0 +X 1372 . C <*> 0 . DP=27;I16=8,19,0,0,954,34882,0,0,1558,91682,0,0,510,11696,0,0;QS=3,0;MQSB=0.601139;MQ0F=0 PL:DP:DV 0,27,251:9:0 0,24,198:8:0 0,30,200:10:0 +X 1373 . C <*> 0 . DP=26;I16=8,17,0,0,892,32692,0,0,1438,84482,0,0,486,11044,0,0;QS=3,0;MQSB=0.612391;MQ0F=0 PL:DP:DV 0,24,243:8:0 0,21,186:7:0 0,30,195:10:0 +X 1374 . C <*> 0 . DP=26;I16=8,17,0,0,953,36553,0,0,1438,84482,0,0,487,11039,0,0;QS=3,0;MQSB=0.612391;MQ0F=0 PL:DP:DV 0,24,249:8:0 0,21,193:7:0 0,30,211:10:0 +X 1375 . T <*> 0 . DP=27;I16=9,18,0,0,1011,38377,0,0,1558,91682,0,0,512,11630,0,0;QS=3,0;MQSB=0.651439;MQ0F=0 PL:DP:DV 0,27,243:9:0 0,24,215:8:0 0,30,215:10:0 +X 1376 . A <*> 0 . DP=27;I16=9,17,0,0,912,32444,0,0,1498,88082,0,0,488,10992,0,0;QS=3,0;MQSB=0.657209;MQ0F=0 PL:DP:DV 0,27,234:9:0 0,21,198:7:0 0,30,195:10:0 +X 1377 . A <*> 0 . DP=26;I16=9,17,0,0,994,38518,0,0,1498,88082,0,0,515,11625,0,0;QS=3,0;MQSB=0.657209;MQ0F=0 PL:DP:DV 0,24,228:8:0 0,24,221:8:0 0,30,228:10:0 +X 1378 . G <*> 0 . DP=26;I16=9,17,0,0,910,33180,0,0,1498,88082,0,0,517,11653,0,0;QS=3,0;MQSB=0.657209;MQ0F=0 PL:DP:DV 0,24,234:8:0 0,24,199:8:0 0,30,197:10:0 +X 1379 . C <*> 0 . DP=26;I16=9,17,0,0,891,31779,0,0,1498,88082,0,0,519,11701,0,0;QS=3,0;MQSB=0.657209;MQ0F=0 PL:DP:DV 0,24,228:8:0 0,24,198:8:0 0,30,193:10:0 +X 1380 . C <*> 0 . DP=26;I16=9,17,0,0,925,33925,0,0,1498,88082,0,0,520,11720,0,0;QS=3,0;MQSB=0.657209;MQ0F=0 PL:DP:DV 0,24,226:8:0 0,24,202:8:0 0,30,209:10:0 +X 1381 . C <*> 0 . DP=28;I16=10,18,0,0,878,28560,0,0,1618,95282,0,0,521,11761,0,0;QS=3,0;MQSB=0.689069;MQ0F=0 PL:DP:DV 0,24,211:8:0 0,24,177:8:0 0,36,208:12:0 +X 1382 . G <*> 0 . DP=28;I16=8,18,0,0,905,32553,0,0,1529,90841,0,0,482,10912,0,0;QS=3,0;MQSB=0.882497;MQ0F=0 PL:DP:DV 0,24,213:8:0 0,18,152:6:0 0,36,243:12:0 +X 1383 . C <*> 0 . DP=27;I16=10,16,0,0,897,32373,0,0,1498,88082,0,0,502,11242,0,0;QS=3,0;MQSB=0.700784;MQ0F=0 PL:DP:DV 0,24,225:8:0 0,21,163:7:0 0,33,241:11:0 +X 1384 . C <*> 0 . DP=28;I16=11,17,0,0,980,35558,0,0,1618,95282,0,0,529,11885,0,0;QS=3,0;MQSB=0.726331;MQ0F=0 PL:DP:DV 0,27,248:9:0 0,24,184:8:0 0,33,239:11:0 +X 1385 . A <*> 0 . DP=30;I16=11,18,0,0,949,33215,0,0,1678,98882,0,0,508,11356,0,0;QS=3,0;MQSB=0.720887;MQ0F=0 PL:DP:DV 0,30,232:10:0 0,27,185:9:0 0,30,234:10:0 +X 1386 . C <*> 0 . DP=30;I16=11,19,0,0,1088,39938,0,0,1738,102482,0,0,537,12011,0,0;QS=3,0;MQSB=0.715831;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,27,218:9:0 0,33,255:11:0 +X 1387 . C <*> 0 . DP=31;I16=12,19,0,0,1101,40297,0,0,1798,106082,0,0,540,12022,0,0;QS=3,0;MQSB=0.743137;MQ0F=0 PL:DP:DV 0,33,250:11:0 0,27,219:9:0 0,33,252:11:0 +X 1388 . C <*> 0 . DP=31;I16=11,19,0,0,999,34081,0,0,1769,105241,0,0,519,11439,0,0;QS=3,0;MQSB=0.91982;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,185:8:0 0,33,211:11:0 +X 1389 . G <*> 0 . DP=31;I16=11,19,0,0,1065,39119,0,0,1738,102482,0,0,535,11941,0,0;QS=3,0;MQSB=0.715831;MQ0F=0 PL:DP:DV 0,27,234:9:0 0,30,234:10:0 0,33,255:11:0 +X 1390 . G <*> 0 . DP=31;I16=12,19,0,0,1152,43744,0,0,1798,106082,0,0,555,12241,0,0;QS=3,0;MQSB=0.743137;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,30,245:10:0 0,33,255:11:0 +X 1391 . A <*> 0 . DP=31;I16=12,19,0,0,1241,50255,0,0,1798,106082,0,0,560,12326,0,0;QS=3,0;MQSB=0.743137;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,30,255:10:0 0,33,255:11:0 +X 1392 . G <*> 0 . DP=31;I16=12,19,0,0,1160,44364,0,0,1798,106082,0,0,564,12392,0,0;QS=3,0;MQSB=0.743137;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,30,250:10:0 0,33,255:11:0 +X 1393 . A <*> 0 . DP=31;I16=12,19,0,0,1123,41811,0,0,1798,106082,0,0,568,12490,0,0;QS=3,0;MQSB=0.743137;MQ0F=0 PL:DP:DV 0,30,228:10:0 0,30,255:10:0 0,33,255:11:0 +X 1394 . C <*> 0 . DP=31;I16=12,19,0,0,1139,42555,0,0,1798,106082,0,0,571,12569,0,0;QS=3,0;MQSB=0.743137;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,30,244:10:0 0,33,255:11:0 +X 1395 . A <*> 0 . DP=31;I16=12,19,0,0,1206,48048,0,0,1798,106082,0,0,575,12677,0,0;QS=3,0;MQSB=0.743137;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,240:9:0 0,33,255:11:0 +X 1396 . G <*> 0 . DP=31;I16=12,19,0,0,1196,46882,0,0,1798,106082,0,0,579,12763,0,0;QS=3,0;MQSB=0.743137;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,249:9:0 0,33,255:11:0 +X 1397 . C <*> 0 . DP=31;I16=12,18,0,0,993,33339,0,0,1738,102482,0,0,579,12775,0,0;QS=3,0;MQSB=0.748022;MQ0F=0 PL:DP:DV 0,30,231:10:0 0,27,205:9:0 0,33,217:11:0 +X 1398 . G <*> 0 . DP=30;I16=12,18,0,0,1055,38309,0,0,1738,102482,0,0,584,12826,0,0;QS=3,0;MQSB=0.748022;MQ0F=0 PL:DP:DV 0,33,250:11:0 0,27,229:9:0 0,30,244:10:0 +X 1399 . G <*> 0 . DP=30;I16=12,18,0,0,1132,43666,0,0,1738,102482,0,0,586,12854,0,0;QS=3,0;MQSB=0.748022;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,239:9:0 0,30,255:10:0 +X 1400 . A <*> 0 . DP=30;I16=11,18,0,0,1101,42271,0,0,1678,98882,0,0,563,12289,0,0;QS=3,0;MQSB=0.720887;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,27,239:9:0 0,30,246:10:0 +X 1401 . T <*> 0 . DP=30;I16=12,18,0,0,1130,44170,0,0,1738,102482,0,0,589,12955,0,0;QS=3,0;MQSB=0.748022;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,251:9:0 0,30,255:10:0 +X 1402 . T <*> 0 . DP=31;I16=13,18,0,0,1152,44058,0,0,1798,106082,0,0,589,12977,0,0;QS=3,0;MQSB=0.771348;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,244:9:0 0,30,255:10:0 +X 1403 . T <*> 0 . DP=31;I16=13,18,0,0,1178,45296,0,0,1798,106082,0,0,590,13032,0,0;QS=3,0;MQSB=0.771348;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,249:9:0 0,30,255:10:0 +X 1404 . C <*> 0 . DP=31;I16=13,18,0,0,1102,40838,0,0,1798,106082,0,0,591,13121,0,0;QS=3,0;MQSB=0.771348;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,236:9:0 0,30,244:10:0 +X 1405 . C <*> 0 . DP=30;I16=12,18,0,0,1154,45216,0,0,1738,102482,0,0,593,13243,0,0;QS=3,0;MQSB=0.748022;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,241:9:0 0,27,229:9:0 +X 1406 . T <*> 0 . DP=30;I16=12,18,0,0,1153,44919,0,0,1738,102482,0,0,595,13397,0,0;QS=3,0;MQSB=0.748022;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,248:9:0 0,27,223:9:0 +X 1407 . T <*> 0 . DP=30;I16=11,18,0,0,1074,40182,0,0,1678,98882,0,0,570,12856,0,0;QS=3,0;MQSB=0.720887;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,231:9:0 0,27,215:9:0 +X 1408 . A <*> 0 . DP=30;I16=12,18,0,0,1131,43363,0,0,1738,102482,0,0,596,13592,0,0;QS=3,0;MQSB=0.748022;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,30,244:10:0 0,27,234:9:0 +X 1409 . G <*> 0 . DP=29;I16=12,17,0,0,1082,40752,0,0,1678,98882,0,0,599,13729,0,0;QS=3,0;MQSB=0.753269;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,237:9:0 0,27,204:9:0 +X 1410 . T <*> 0 . DP=29;I16=12,17,0,0,1084,41030,0,0,1678,98882,0,0,601,13841,0,0;QS=3,0;MQSB=0.753269;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,239:9:0 0,27,218:9:0 +X 1411 . T <*> 0 . DP=29;I16=12,17,0,0,958,32550,0,0,1678,98882,0,0,600,13826,0,0;QS=3,0;MQSB=0.753269;MQ0F=0 PL:DP:DV 0,33,250:11:0 0,27,206:9:0 0,27,194:9:0 +X 1412 . A T,<*> 0 . DP=29;I16=11,17,1,0,924,31586,25,625,1649,98041,29,841,573,13159,24,576;QS=2.90842,0.0915751,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.753269;BQB=1;MQ0F=0 PL:DP:DV 0,33,245,33,245,245:11:0 0,2,171,24,174,187:9:1 0,27,192,27,192,192:9:0 +X 1413 . C <*> 0 . DP=29;I16=12,17,0,0,1067,39941,0,0,1678,98882,0,0,591,13521,0,0;QS=3,0;MQSB=0.753269;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,230:9:0 0,27,209:9:0 +X 1414 . T <*> 0 . DP=29;I16=12,17,0,0,1123,44271,0,0,1678,98882,0,0,585,13335,0,0;QS=3,0;MQSB=0.753269;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,236:9:0 0,27,221:9:0 +X 1415 . T <*> 0 . DP=29;I16=12,17,0,0,1000,35254,0,0,1678,98882,0,0,577,13077,0,0;QS=3,0;MQSB=0.753269;MQ0F=0 PL:DP:DV 0,33,246:11:0 0,27,216:9:0 0,27,208:9:0 +X 1416 . A <*> 0 . DP=30;I16=13,17,0,0,1026,36124,0,0,1738,102482,0,0,569,12847,0,0;QS=3,0;MQSB=0.776389;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,208:9:0 0,27,199:9:0 +X 1417 . C <*> 0 . DP=29;I16=13,16,0,0,1111,42941,0,0,1678,98882,0,0,563,12645,0,0;QS=3,0;MQSB=0.781802;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,235:9:0 0,24,211:8:0 +X 1418 . T <*> 0 . DP=29;I16=13,16,0,0,1111,43021,0,0,1678,98882,0,0,557,12471,0,0;QS=3,0;MQSB=0.781802;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,231:9:0 0,24,207:8:0 +X 1419 . A <*> 0 . DP=29;I16=13,16,0,0,1039,38191,0,0,1678,98882,0,0,551,12325,0,0;QS=3,0;MQSB=0.781802;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,222:9:0 0,24,199:8:0 +X 1420 . T <*> 0 . DP=29;I16=13,16,0,0,1039,37885,0,0,1678,98882,0,0,544,12158,0,0;QS=3,0;MQSB=0.781802;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,234:9:0 0,24,185:8:0 +X 1421 . G <*> 0 . DP=31;I16=13,18,0,0,1129,41649,0,0,1798,106082,0,0,536,11970,0,0;QS=3,0;MQSB=0.771348;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,30,247:10:0 0,24,191:8:0 +X 1422 . C <*> 0 . DP=29;I16=13,16,0,0,1075,40645,0,0,1678,98882,0,0,532,11810,0,0;QS=3,0;MQSB=0.781802;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,30,239:10:0 0,18,180:6:0 +X 1423 . T <*> 0 . DP=31;I16=14,17,0,0,1179,45767,0,0,1798,106082,0,0,528,11678,0,0;QS=3,0;MQSB=0.79638;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,36,255:12:0 0,18,183:6:0 +X 1424 . C <*> 0 . DP=30;I16=13,17,0,0,1086,40448,0,0,1738,102482,0,0,527,11575,0,0;QS=3,0;MQSB=0.776389;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,36,255:12:0 0,18,174:6:0 +X 1425 . C <*> 0 . DP=30;I16=13,17,0,0,1124,42974,0,0,1738,102482,0,0,525,11453,0,0;QS=3,0;MQSB=0.776389;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,36,255:12:0 0,18,180:6:0 +X 1426 . T <*> 0 . DP=32;I16=15,17,0,0,1218,47130,0,0,1858,109682,0,0,523,11363,0,0;QS=3,0;MQSB=0.813784;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,36,255:12:0 0,18,188:6:0 +X 1427 . T <*> 0 . DP=32;I16=14,18,0,0,1126,40772,0,0,1827,106923,0,0,524,11306,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,36,255:12:0 0,18,176:6:0 +X 1428 . G <*> 0 . DP=33;I16=15,18,0,0,1188,43596,0,0,1887,110523,0,0,525,11233,0,0;QS=3,0;MQSB=0.930476;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,36,255:12:0 0,18,166:6:0 +X 1429 . G <*> 0 . DP=33;I16=14,18,0,0,1070,37720,0,0,1858,109682,0,0,507,10795,0,0;QS=3,0;MQSB=0.997118;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,33,243:11:0 0,18,148:6:0 +X 1430 . C <*> 0 . DP=33;I16=15,18,0,0,1145,40795,0,0,1887,110523,0,0,529,11193,0,0;QS=3,0;MQSB=0.930476;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,36,247:12:0 0,18,157:6:0 +X 1431 . C <*> 0 . DP=33;I16=15,18,0,0,1160,41686,0,0,1887,110523,0,0,531,11227,0,0;QS=3,0;MQSB=0.930476;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,36,253:12:0 0,18,167:6:0 +X 1432 . A <*> 0 . DP=33;I16=15,18,0,0,1118,39032,0,0,1887,110523,0,0,533,11297,0,0;QS=3,0;MQSB=0.930476;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,36,255:12:0 0,18,169:6:0 +X 1433 . T <*> 0 . DP=34;I16=15,19,0,0,1238,45602,0,0,1947,114123,0,0,535,11403,0,0;QS=3,0;MQSB=0.923533;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,36,255:12:0 0,18,174:6:0 +X 1434 . T <*> 0 . DP=35;I16=15,20,0,0,1269,46757,0,0,2007,117723,0,0,537,11495,0,0;QS=3,0;MQSB=0.916855;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,36,255:12:0 0,18,179:6:0 +X 1435 . T <*> 0 . DP=35;I16=14,20,0,0,1256,46868,0,0,1947,114123,0,0,515,10999,0,0;QS=3,0;MQSB=0.901704;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,36,255:12:0 0,18,180:6:0 +X 1436 . C <*> 0 . DP=34;I16=14,20,0,0,1250,46978,0,0,1947,114123,0,0,544,11790,0,0;QS=3,0;MQSB=0.901704;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,36,255:12:0 0,18,165:6:0 +X 1437 . T <*> 0 . DP=32;I16=13,19,0,0,1222,47206,0,0,1858,109682,0,0,548,11892,0,0;QS=3,0;MQSB=0.993397;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,33,255:11:0 0,15,161:5:0 +X 1438 . C <*> 0 . DP=30;I16=13,17,0,0,1132,43284,0,0,1738,102482,0,0,554,12028,0,0;QS=3,0;MQSB=0.996503;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,30,251:10:0 0,15,159:5:0 +X 1439 . T <*> 0 . DP=30;I16=13,17,0,0,1110,41602,0,0,1738,102482,0,0,560,12196,0,0;QS=3,0;MQSB=0.996503;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,30,255:10:0 0,15,156:5:0 +X 1440 . A <*> 0 . DP=30;I16=12,16,0,0,1062,41028,0,0,1618,95282,0,0,550,12106,0,0;QS=3,0;MQSB=0.995699;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,255:9:0 0,12,144:4:0 +X 1441 . G <*> 0 . DP=30;I16=13,17,0,0,1138,44104,0,0,1738,102482,0,0,574,12576,0,0;QS=3,0;MQSB=0.996503;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,30,244:10:0 0,12,137:4:0 +X 1442 . G <*> 0 . DP=30;I16=13,17,0,0,1064,38534,0,0,1738,102482,0,0,580,12740,0,0;QS=3,0;MQSB=0.996503;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,30,242:10:0 0,12,128:4:0 +X 1443 . T <*> 0 . DP=30;I16=12,17,0,0,1013,36225,0,0,1678,98882,0,0,568,12598,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,30,230:10:0 0,12,133:4:0 +X 1444 . A <*> 0 . DP=30;I16=12,17,0,0,968,33936,0,0,1678,98882,0,0,569,12627,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,27,205:9:0 0,12,132:4:0 +X 1445 . T <*> 0 . DP=30;I16=14,15,0,0,1053,39129,0,0,1678,98882,0,0,585,13161,0,0;QS=3,0;MQSB=0.999762;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,237:9:0 0,15,169:5:0 +X 1446 . T <*> 0 . DP=30;I16=13,16,0,0,1051,38675,0,0,1678,98882,0,0,579,12951,0,0;QS=3,0;MQSB=0.997839;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,229:8:0 0,15,164:5:0 +X 1447 . G <*> 0 . DP=30;I16=14,16,0,0,1110,42692,0,0,1738,102482,0,0,606,13612,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,27,229:9:0 0,15,157:5:0 +X 1448 . G <*> 0 . DP=30;I16=13,16,0,0,1037,37759,0,0,1678,98882,0,0,585,13151,0,0;QS=3,0;MQSB=0.997839;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,217:8:0 0,15,150:5:0 +X 1449 . T <*> 0 . DP=30;I16=14,16,0,0,1051,37869,0,0,1738,102482,0,0,612,13870,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,27,230:9:0 0,15,152:5:0 +X 1450 . A <*> 0 . DP=29;I16=13,15,0,0,1039,38785,0,0,1649,98041,0,0,604,13842,0,0;QS=3,0;MQSB=0.956162;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,224:8:0 0,15,165:5:0 +X 1451 . T <*> 0 . DP=29;I16=13,16,0,0,1046,38586,0,0,1709,101641,0,0,616,14042,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,228:8:0 0,15,158:5:0 +X 1452 . A <*> 0 . DP=31;I16=14,16,0,0,1066,38696,0,0,1769,105241,0,0,604,13924,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,218:8:0 0,15,147:5:0 +X 1453 . T <*> 0 . DP=31;I16=13,17,0,0,1107,42059,0,0,1769,105241,0,0,592,13444,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,199:7:0 0,15,165:5:0 +X 1454 . T <*> 0 . DP=31;I16=14,17,0,0,1139,42711,0,0,1829,108841,0,0,617,14045,0,0;QS=3,0;MQSB=0.962133;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,234:8:0 0,15,166:5:0 +X 1455 . G <*> 0 . DP=31;I16=13,17,0,0,1107,41765,0,0,1769,105241,0,0,592,13420,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,197:7:0 0,15,148:5:0 +X 1456 . T <*> 0 . DP=31;I16=14,17,0,0,1139,42717,0,0,1829,108841,0,0,617,14069,0,0;QS=3,0;MQSB=0.962133;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,215:8:0 0,15,170:5:0 +X 1457 . G <*> 0 . DP=31;I16=14,17,0,0,1129,42071,0,0,1829,108841,0,0,615,14019,0,0;QS=3,0;MQSB=0.962133;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,212:8:0 0,15,164:5:0 +X 1458 . T <*> 0 . DP=31;I16=14,17,0,0,1101,40243,0,0,1829,108841,0,0,613,13997,0,0;QS=3,0;MQSB=0.962133;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,220:8:0 0,15,165:5:0 +X 1459 . C A,<*> 0 . DP=31;I16=14,16,0,1,1164,45842,24,576,1769,105241,60,3600,608,13948,2,4;QS=2.87234,0.12766,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.962133;BQB=1;MQ0F=0 PL:DP:DV 0,54,255,54,255,255:18:0 0,24,224,24,224,224:8:0 9,0,135,21,138,152:5:1 +X 1460 . T <*> 0 . DP=32;I16=15,17,0,0,1243,48813,0,0,1889,112441,0,0,605,13833,0,0;QS=3,0;MQSB=0.960687;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,240:8:0 0,15,170:5:0 +X 1461 . G <*> 0 . DP=32;I16=15,17,0,0,1171,44033,0,0,1889,112441,0,0,600,13692,0,0;QS=3,0;MQSB=0.960687;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,224:8:0 0,15,157:5:0 +X 1462 . C <*> 0 . DP=30;I16=14,15,0,0,1102,42216,0,0,1709,101641,0,0,579,13241,0,0;QS=3,0;MQSB=0.954405;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,202:7:0 0,9,112:3:0 +X 1463 . T <*> 0 . DP=30;I16=15,15,0,0,1128,43348,0,0,1769,105241,0,0,592,13396,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,209:7:0 0,12,139:4:0 +X 1464 . G <*> 0 . DP=31;I16=14,16,0,0,1095,40557,0,0,1769,105241,0,0,563,12665,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,186:6:0 0,15,144:5:0 +X 1465 . T <*> 0 . DP=31;I16=15,16,0,0,1143,42557,0,0,1829,108841,0,0,584,13164,0,0;QS=3,0;MQSB=0.957006;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,204:7:0 0,15,166:5:0 +X 1466 . G <*> 0 . DP=31;I16=15,16,0,0,1122,42294,0,0,1829,108841,0,0,580,13018,0,0;QS=3,0;MQSB=0.957006;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,206:7:0 0,15,163:5:0 +X 1467 . A <*> 0 . DP=31;I16=14,16,0,0,1031,36341,0,0,1769,105241,0,0,569,12803,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,195:7:0 0,15,155:5:0 +X 1468 . A <*> 0 . DP=30;I16=15,15,0,0,991,34477,0,0,1769,105241,0,0,573,12717,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,177:7:0 0,15,158:5:0 +X 1469 . C T,<*> 0 . DP=31;I16=13,15,1,0,1013,37887,38,1444,1649,98041,60,3600,536,12106,9,81;QS=2.94025,0.0597484,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.954405;BQB=1;MQ0F=0 PL:DP:DV 0,16,255,51,255,255:18:1 0,18,178,18,178,178:6:0 0,15,160,15,160,160:5:0 +X 1470 . T <*> 0 . DP=31;I16=16,15,0,0,1110,41070,0,0,1829,108841,0,0,567,12489,0,0;QS=3,0;MQSB=0.951229;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,210:7:0 0,15,165:5:0 +X 1471 . G <*> 0 . DP=30;I16=16,14,0,0,1051,38425,0,0,1769,105241,0,0,564,12348,0,0;QS=3,0;MQSB=0.946202;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,192:7:0 0,12,128:4:0 +X 1472 . T <*> 0 . DP=30;I16=16,14,0,0,1049,38097,0,0,1769,105241,0,0,561,12237,0,0;QS=3,0;MQSB=0.946202;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,200:7:0 0,12,134:4:0 +X 1473 . C <*> 0 . DP=30;I16=16,14,0,0,1058,38526,0,0,1769,105241,0,0,558,12156,0,0;QS=3,0;MQSB=0.946202;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,175:7:0 0,12,140:4:0 +X 1474 . C <*> 0 . DP=30;I16=16,14,0,0,1120,42756,0,0,1769,105241,0,0,555,12105,0,0;QS=3,0;MQSB=0.946202;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,202:7:0 0,12,141:4:0 +X 1475 . T <*> 0 . DP=29;I16=14,14,0,0,1047,40395,0,0,1649,98041,0,0,537,11827,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,208:7:0 0,12,155:4:0 +X 1476 . T G,<*> 0 . DP=31;I16=15,15,1,0,1056,37884,14,196,1769,105241,60,3600,566,12614,10,100;QS=2.944,0.056,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.951229;BQB=1;MQ0F=0 PL:DP:DV 0,57,255,57,255,255:19:0 0,9,177,21,180,183:8:1 0,12,140,12,140,140:4:0 +X 1477 . G <*> 0 . DP=31;I16=16,15,0,0,1150,43390,0,0,1829,108841,0,0,574,12700,0,0;QS=3,0;MQSB=0.951229;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,217:8:0 0,12,138:4:0 +X 1478 . G <*> 0 . DP=31;I16=14,15,0,0,1008,36638,0,0,1709,101641,0,0,542,11982,0,0;QS=3,0;MQSB=0.954405;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,208:8:0 0,9,109:3:0 +X 1479 . C <*> 0 . DP=30;I16=15,15,0,0,1061,38671,0,0,1769,105241,0,0,564,12556,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,211:8:0 0,9,106:3:0 +X 1480 . C <*> 0 . DP=30;I16=15,15,0,0,1083,40355,0,0,1769,105241,0,0,561,12531,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,220:8:0 0,9,103:3:0 +X 1481 . T <*> 0 . DP=30;I16=15,15,0,0,1102,41308,0,0,1769,105241,0,0,558,12532,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,235:8:0 0,9,105:3:0 +X 1482 . G <*> 0 . DP=29;I16=15,14,0,0,1044,38550,0,0,1709,101641,0,0,556,12558,0,0;QS=3,0;MQSB=0.947838;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,210:8:0 0,6,75:2:0 +X 1483 . T <*> 0 . DP=31;I16=14,16,0,0,1042,37190,0,0,1769,105241,0,0,521,11919,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,215:7:0 0,9,100:3:0 +X 1484 . T <*> 0 . DP=31;I16=15,16,0,0,1067,37837,0,0,1829,108841,0,0,547,12587,0,0;QS=3,0;MQSB=0.957006;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,24,216:8:0 0,9,106:3:0 +X 1485 . T <*> 0 . DP=30;I16=15,15,0,0,1027,35863,0,0,1769,105241,0,0,549,12659,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,209:8:0 0,9,93:3:0 +X 1486 . G <*> 0 . DP=29;I16=15,14,0,0,1089,41679,0,0,1709,101641,0,0,551,12707,0,0;QS=3,0;MQSB=0.947838;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,198:7:0 0,9,108:3:0 +X 1487 . G <*> 0 . DP=28;I16=14,14,0,0,973,34723,0,0,1649,98041,0,0,554,12778,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,196:7:0 0,9,97:3:0 +X 1488 . T <*> 0 . DP=28;I16=13,14,0,0,928,32432,0,0,1589,94441,0,0,532,12246,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,176:6:0 0,9,102:3:0 +X 1489 . G <*> 0 . DP=27;I16=13,14,0,0,958,35292,0,0,1589,94441,0,0,535,12361,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,174:6:0 0,9,93:3:0 +X 1490 . A <*> 0 . DP=27;I16=13,14,0,0,928,33108,0,0,1589,94441,0,0,538,12446,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,160:5:0 0,9,94:3:0 +X 1491 . C <*> 0 . DP=27;I16=12,13,0,0,798,26812,0,0,1469,87241,0,0,499,11587,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,108:4:0 0,9,79:3:0 +X 1492 . G <*> 0 . DP=27;I16=13,14,0,0,893,30927,0,0,1589,94441,0,0,543,12527,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,136:5:0 0,9,100:3:0 +X 1493 . G <*> 0 . DP=27;I16=13,13,0,0,907,32761,0,0,1529,90841,0,0,520,11948,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,155:5:0 0,9,106:3:0 +X 1494 . G <*> 0 . DP=27;I16=13,14,0,0,939,33599,0,0,1589,94441,0,0,547,12639,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,156:5:0 0,9,107:3:0 +X 1495 . T <*> 0 . DP=26;I16=12,13,0,0,814,27700,0,0,1469,87241,0,0,524,12048,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,143:5:0 0,9,105:3:0 +X 1496 . G <*> 0 . DP=26;I16=13,13,0,0,969,36751,0,0,1529,90841,0,0,550,12674,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,157:5:0 0,9,107:3:0 +X 1497 . A <*> 0 . DP=27;I16=12,14,0,0,904,32740,0,0,1529,90841,0,0,525,12019,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,166:5:0 0,9,113:3:0 +X 1498 . G <*> 0 . DP=27;I16=13,14,0,0,1002,37852,0,0,1589,94441,0,0,551,12635,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,153:5:0 0,9,112:3:0 +X 1499 . G <*> 0 . DP=28;I16=14,14,0,0,973,34891,0,0,1649,98041,0,0,551,12599,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,146:5:0 0,9,108:3:0 +X 1500 . A <*> 0 . DP=28;I16=14,14,0,0,1023,38115,0,0,1649,98041,0,0,552,12588,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,165:5:0 0,9,115:3:0 +X 1501 . G <*> 0 . DP=28;I16=14,14,0,0,1051,40105,0,0,1649,98041,0,0,551,12505,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,163:5:0 0,9,100:3:0 +X 1502 . C <*> 0 . DP=27;I16=13,14,0,0,963,35241,0,0,1589,94441,0,0,549,12351,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,140:5:0 0,9,105:3:0 +X 1503 . A <*> 0 . DP=28;I16=14,14,0,0,1026,38252,0,0,1649,98041,0,0,546,12176,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,171:5:0 0,9,109:3:0 +X 1504 . G <*> 0 . DP=28;I16=13,14,0,0,1052,41226,0,0,1589,94441,0,0,523,11591,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,163:5:0 0,9,111:3:0 +X 1505 . G <*> 0 . DP=28;I16=14,13,0,0,959,35545,0,0,1589,94441,0,0,517,11295,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,155:5:0 0,9,114:3:0 +X 1506 . G <*> 0 . DP=28;I16=14,14,0,0,1013,37355,0,0,1649,98041,0,0,540,11840,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,139:5:0 0,9,112:3:0 +X 1507 . A <*> 0 . DP=28;I16=14,14,0,0,987,35217,0,0,1649,98041,0,0,538,11792,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,162:5:0 0,9,114:3:0 +X 1508 . C <*> 0 . DP=28;I16=14,14,0,0,1033,38663,0,0,1649,98041,0,0,535,11727,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,137:5:0 0,9,112:3:0 +X 1509 . A <*> 0 . DP=28;I16=15,13,0,0,1028,38610,0,0,1649,98041,0,0,529,11493,0,0;QS=3,0;MQSB=0.942064;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,12,128:4:0 0,9,122:3:0 +X 1510 . G <*> 0 . DP=28;I16=15,13,0,0,1064,40824,0,0,1649,98041,0,0,524,11288,0,0;QS=3,0;MQSB=0.942064;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,12,132:4:0 0,9,111:3:0 +X 1511 . A <*> 0 . DP=28;I16=15,13,0,0,976,34794,0,0,1649,98041,0,0,519,11113,0,0;QS=3,0;MQSB=0.942064;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,12,136:4:0 0,9,110:3:0 +X 1512 . A <*> 0 . DP=28;I16=15,12,0,0,998,37460,0,0,1589,94441,0,0,489,10343,0,0;QS=3,0;MQSB=0.935229;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,142:4:0 0,9,110:3:0 +X 1513 . G <*> 0 . DP=28;I16=14,13,0,0,1014,38940,0,0,1589,94441,0,0,497,10709,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,134:4:0 0,9,108:3:0 +X 1514 . G <*> 0 . DP=28;I16=15,13,0,0,1054,39954,0,0,1649,98041,0,0,504,10768,0,0;QS=3,0;MQSB=0.942064;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,12,134:4:0 0,9,108:3:0 +X 1515 . G <*> 0 . DP=28;I16=14,13,0,0,948,34152,0,0,1589,94441,0,0,488,10564,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,133:4:0 0,9,101:3:0 +X 1516 . T <*> 0 . DP=27;I16=12,13,0,0,811,27385,0,0,1469,87241,0,0,472,10338,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,117:4:0 0,9,106:3:0 +X 1517 . C <*> 0 . DP=27;I16=13,13,0,0,943,35153,0,0,1529,90841,0,0,478,10380,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,12,134:4:0 0,9,97:3:0 +X 1518 . C <*> 0 . DP=28;I16=13,12,0,0,908,33852,0,0,1469,87241,0,0,427,9261,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,132:4:0 0,9,96:3:0 +X 1519 . T <*> 0 . DP=28;I16=15,13,0,0,988,35808,0,0,1649,98041,0,0,475,10337,0,0;QS=3,0;MQSB=0.942064;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,154:5:0 0,9,110:3:0 +X 1520 . G <*> 0 . DP=29;I16=16,13,0,0,1005,36307,0,0,1709,101641,0,0,470,10328,0,0;QS=3,0;MQSB=0.940317;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,18,150:6:0 0,9,104:3:0 +X 1521 . C <*> 0 . DP=28;I16=16,12,0,0,900,30324,0,0,1649,98041,0,0,466,10300,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,164:6:0 0,9,88:3:0 +X 1522 . G <*> 0 . DP=27;I16=15,10,0,0,784,25144,0,0,1469,87241,0,0,442,9956,0,0;QS=3,0;MQSB=0.9171;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,110:5:0 0,9,91:3:0 +X 1523 . T <*> 0 . DP=27;I16=16,11,0,0,921,32001,0,0,1589,94441,0,0,457,10189,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,136:5:0 0,9,108:3:0 +X 1524 . G <*> 0 . DP=27;I16=16,10,0,0,932,34140,0,0,1529,90841,0,0,453,10153,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,12,108:4:0 0,9,103:3:0 +X 1525 . C <*> 0 . DP=27;I16=16,11,0,0,972,35704,0,0,1589,94441,0,0,473,10719,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,113:4:0 0,9,112:3:0 +X 1526 . C <*> 0 . DP=25;I16=14,11,0,0,883,31843,0,0,1469,87241,0,0,470,10684,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,109:4:0 0,9,106:3:0 +X 1527 . C <*> 0 . DP=24;I16=14,10,0,0,867,31999,0,0,1440,86400,0,0,466,10572,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,107:4:0 0,9,112:3:0 +X 1528 . T <*> 0 . DP=23;I16=13,10,0,0,869,33133,0,0,1380,82800,0,0,463,10483,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,114:4:0 0,9,113:3:0 +X 1529 . G <*> 0 . DP=23;I16=13,10,0,0,812,29432,0,0,1380,82800,0,0,459,10365,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,108:4:0 0,9,104:3:0 +X 1530 . C <*> 0 . DP=24;I16=13,10,0,0,819,30073,0,0,1380,82800,0,0,446,10186,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,137:5:0 0,9,106:3:0 +X 1531 . C <*> 0 . DP=24;I16=13,11,0,0,877,32969,0,0,1440,86400,0,0,452,10190,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,144:5:0 0,9,105:3:0 +X 1532 . T <*> 0 . DP=24;I16=13,11,0,0,887,33721,0,0,1440,86400,0,0,449,10135,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,165:5:0 0,9,120:3:0 +X 1533 . T <*> 0 . DP=23;I16=13,10,0,0,793,27987,0,0,1380,82800,0,0,447,10101,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,146:5:0 0,9,107:3:0 +X 1534 . C <*> 0 . DP=23;I16=14,9,0,0,847,31627,0,0,1380,82800,0,0,446,10086,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,153:5:0 0,9,109:3:0 +X 1535 . A <*> 0 . DP=23;I16=14,9,0,0,770,26604,0,0,1380,82800,0,0,444,9990,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,144:5:0 0,9,99:3:0 +X 1536 . C <*> 0 . DP=24;I16=15,9,0,0,826,28984,0,0,1440,86400,0,0,442,9914,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,138:5:0 0,9,110:3:0 +X 1537 . A <*> 0 . DP=24;I16=14,9,0,0,844,31384,0,0,1380,82800,0,0,416,9234,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,149:5:0 0,9,115:3:0 +X 1538 . A <*> 0 . DP=24;I16=15,9,0,0,909,34727,0,0,1440,86400,0,0,440,9826,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,154:5:0 0,9,112:3:0 +X 1539 . G <*> 0 . DP=24;I16=15,9,0,0,913,35327,0,0,1440,86400,0,0,439,9815,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,149:5:0 0,9,117:3:0 +X 1540 . C <*> 0 . DP=23;I16=15,8,0,0,828,30260,0,0,1380,82800,0,0,438,9776,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,146:5:0 0,9,102:3:0 +X 1541 . C <*> 0 . DP=23;I16=15,8,0,0,823,30615,0,0,1380,82800,0,0,437,9759,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,142:5:0 0,9,108:3:0 +X 1542 . C <*> 0 . DP=25;I16=16,8,0,0,893,33843,0,0,1440,86400,0,0,435,9715,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,147:5:0 0,12,131:4:0 +X 1543 . C <*> 0 . DP=25;I16=16,8,0,0,880,33206,0,0,1440,86400,0,0,434,9696,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,141:5:0 0,12,136:4:0 +X 1544 . T <*> 0 . DP=25;I16=16,8,0,0,899,34405,0,0,1440,86400,0,0,431,9603,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,150:5:0 0,12,148:4:0 +X 1545 . G <*> 0 . DP=25;I16=16,8,0,0,874,32636,0,0,1440,86400,0,0,428,9536,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,146:5:0 0,12,129:4:0 +X 1546 . G <*> 0 . DP=24;I16=15,8,0,0,796,28796,0,0,1380,82800,0,0,425,9443,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,130:5:0 0,9,110:3:0 +X 1547 . A <*> 0 . DP=23;I16=15,8,0,0,837,30945,0,0,1380,82800,0,0,448,9996,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,176:6:0 0,9,112:3:0 +X 1548 . A <*> 0 . DP=23;I16=14,8,0,0,812,30830,0,0,1320,79200,0,0,421,9319,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,173:5:0 0,9,115:3:0 +X 1549 . G <*> 0 . DP=23;I16=15,8,0,0,870,33642,0,0,1380,82800,0,0,444,9912,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,174:6:0 0,9,114:3:0 +X 1550 . G <*> 0 . DP=23;I16=15,8,0,0,790,28502,0,0,1380,82800,0,0,442,9900,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,154:6:0 0,9,109:3:0 +X 1551 . A <*> 0 . DP=23;I16=15,8,0,0,802,28596,0,0,1380,82800,0,0,440,9908,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,173:6:0 0,9,107:3:0 +X 1552 . A <*> 0 . DP=21;I16=14,7,0,0,792,30156,0,0,1260,75600,0,0,438,9836,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,196:6:0 0,9,110:3:0 +X 1553 . A <*> 0 . DP=21;I16=13,7,0,0,738,28112,0,0,1200,72000,0,0,411,9159,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,251:11:0 0,18,192:6:0 0,9,115:3:0 +X 1554 . G <*> 0 . DP=21;I16=14,7,0,0,763,28221,0,0,1260,75600,0,0,434,9752,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,171:6:0 0,9,101:3:0 +X 1555 . T <*> 0 . DP=21;I16=14,7,0,0,726,26234,0,0,1260,75600,0,0,432,9740,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,252:12:0 0,18,169:6:0 0,9,108:3:0 +X 1556 . T <*> 0 . DP=21;I16=14,7,0,0,745,26971,0,0,1260,75600,0,0,429,9697,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,253:12:0 0,18,177:6:0 0,9,110:3:0 +X 1557 . G <*> 0 . DP=22;I16=15,7,0,0,801,29689,0,0,1320,79200,0,0,426,9672,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,166:6:0 0,9,101:3:0 +X 1558 . T <*> 0 . DP=22;I16=15,6,0,0,720,25620,0,0,1260,75600,0,0,404,9244,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,131:5:0 0,9,112:3:0 +X 1559 . T <*> 0 . DP=22;I16=15,7,0,0,712,24690,0,0,1320,79200,0,0,417,9439,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,248:13:0 0,18,158:6:0 0,9,103:3:0 +X 1560 . T <*> 0 . DP=21;I16=14,7,0,0,736,26560,0,0,1260,75600,0,0,412,9284,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,251:12:0 0,18,170:6:0 0,9,112:3:0 +X 1561 . T <*> 0 . DP=21;I16=14,7,0,0,706,24776,0,0,1260,75600,0,0,406,9102,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,241:12:0 0,18,174:6:0 0,9,106:3:0 +X 1562 . G <*> 0 . DP=21;I16=14,7,0,0,765,28655,0,0,1260,75600,0,0,399,8893,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,181:6:0 0,9,108:3:0 +X 1563 . G <*> 0 . DP=22;I16=13,7,0,0,713,26255,0,0,1200,72000,0,0,360,8176,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,147:5:0 0,9,108:3:0 +X 1564 . G <*> 0 . DP=22;I16=13,8,0,0,721,25457,0,0,1260,75600,0,0,368,8218,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,173:6:0 0,9,95:3:0 +X 1565 . A <*> 0 . DP=21;I16=14,7,0,0,724,25888,0,0,1260,75600,0,0,380,8352,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,162:6:0 0,6,71:2:0 +X 1566 . T <*> 0 . DP=21;I16=13,7,0,0,698,25286,0,0,1200,72000,0,0,364,8086,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,143:5:0 0,6,78:2:0 +X 1567 . C <*> 0 . DP=20;I16=12,6,0,0,652,24422,0,0,1080,64800,0,0,351,7881,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,104:3:0 0,6,72:2:0 +X 1568 . T <*> 0 . DP=20;I16=13,7,0,0,711,26125,0,0,1200,72000,0,0,363,7871,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,157:5:0 0,6,74:2:0 +X 1569 . C <*> 0 . DP=19;I16=12,6,0,0,676,25850,0,0,1080,64800,0,0,351,7669,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,128:4:0 0,6,76:2:0 +X 1570 . T <*> 0 . DP=19;I16=12,7,0,0,700,26750,0,0,1140,68400,0,0,353,7583,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,149:5:0 0,6,71:2:0 +X 1571 . G <*> 0 . DP=19;I16=12,6,0,0,639,23361,0,0,1080,64800,0,0,343,7441,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,125:4:0 0,6,70:2:0 +X 1572 . C <*> 0 . DP=19;I16=11,6,0,0,640,24568,0,0,1020,61200,0,0,328,7202,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,125:4:0 0,6,70:2:0 +X 1573 . A <*> 0 . DP=19;I16=11,4,0,0,565,21475,0,0,900,54000,0,0,304,6900,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,132:4:0 0,3,40:1:0 +X 1574 . C <*> 0 . DP=19;I16=12,5,0,0,636,24076,0,0,1020,61200,0,0,318,6948,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,128:4:0 0,3,38:1:0 +X 1575 . C <*> 0 . DP=19;I16=11,6,0,0,610,22742,0,0,1020,61200,0,0,296,6272,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,125:4:0 0,6,71:2:0 +X 1576 . C <*> 0 . DP=19;I16=12,6,0,0,675,25821,0,0,1080,64800,0,0,315,6785,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,133:4:0 0,6,78:2:0 +X 1577 . T <*> 0 . DP=17;I16=11,6,0,0,650,25330,0,0,1020,61200,0,0,310,6692,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,118:3:0 0,6,77:2:0 +X 1578 . C <*> 0 . DP=17;I16=10,6,0,0,622,24364,0,0,960,57600,0,0,279,5943,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,84:2:0 0,6,77:2:0 +X 1579 . A <*> 0 . DP=17;I16=11,6,0,0,596,22326,0,0,1020,61200,0,0,298,6464,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,116:3:0 0,6,80:2:0 +X 1580 . G <*> 0 . DP=17;I16=11,6,0,0,651,25195,0,0,1020,61200,0,0,292,6380,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,109:3:0 0,6,77:2:0 +X 1581 . C <*> 0 . DP=17;I16=11,6,0,0,586,21418,0,0,1020,61200,0,0,286,6316,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,103:3:0 0,6,71:2:0 +X 1582 . C <*> 0 . DP=18;I16=11,7,0,0,639,23491,0,0,1080,64800,0,0,280,6272,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,109:3:0 0,6,75:2:0 +X 1583 . T <*> 0 . DP=16;I16=10,6,0,0,591,22349,0,0,960,57600,0,0,276,6196,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,112:3:0 0,6,74:2:0 +X 1584 . G <*> 0 . DP=15;I16=10,5,0,0,563,21283,0,0,900,54000,0,0,272,6086,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,105:3:0 0,3,39:1:0 +X 1585 . G <*> 0 . DP=16;I16=10,5,0,0,494,17160,0,0,900,54000,0,0,251,5703,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,244:11:0 0,9,103:3:0 0,3,30:1:0 +X 1586 . A <*> 0 . DP=15;I16=10,3,0,0,470,17200,0,0,780,46800,0,0,237,5273,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,223:10:0 0,6,79:2:0 0,3,42:1:0 +X 1587 . C <*> 0 . DP=15;I16=11,4,0,0,508,17900,0,0,900,54000,0,0,264,5852,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,247:11:0 0,9,94:3:0 0,3,31:1:0 +X 1588 . A <*> 0 . DP=15;I16=11,4,0,0,511,17939,0,0,900,54000,0,0,262,5806,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,232:11:0 0,9,105:3:0 0,3,41:1:0 +X 1589 . A <*> 0 . DP=15;I16=11,4,0,0,536,19584,0,0,900,54000,0,0,259,5725,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,249:11:0 0,9,106:3:0 0,3,42:1:0 +X 1590 . C <*> 0 . DP=15;I16=10,5,0,0,514,18228,0,0,900,54000,0,0,257,5657,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,231:10:0 0,9,104:3:0 0,6,71:2:0 +X 1591 . T <*> 0 . DP=15;I16=10,5,0,0,515,18559,0,0,900,54000,0,0,256,5602,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,241:10:0 0,9,85:3:0 0,6,73:2:0 +X 1592 . T <*> 0 . DP=15;I16=10,5,0,0,503,17345,0,0,900,54000,0,0,255,5561,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,225:10:0 0,9,107:3:0 0,6,62:2:0 +X 1593 . G <*> 0 . DP=15;I16=10,5,0,0,540,19930,0,0,900,54000,0,0,254,5534,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,9,106:3:0 0,6,60:2:0 +X 1594 . T <*> 0 . DP=15;I16=10,5,0,0,535,19445,0,0,900,54000,0,0,252,5472,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,234:10:0 0,9,106:3:0 0,6,80:2:0 +X 1595 . G <*> 0 . DP=15;I16=10,4,0,0,494,17940,0,0,840,50400,0,0,225,4801,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,213:9:0 0,9,105:3:0 0,6,69:2:0 +X 1596 . C <*> 0 . DP=15;I16=10,4,0,0,479,17011,0,0,840,50400,0,0,233,5151,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,200:9:0 0,9,111:3:0 0,6,74:2:0 +X 1597 . C <*> 0 . DP=15;I16=10,5,0,0,489,16941,0,0,900,54000,0,0,245,5285,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,195:9:0 0,12,127:4:0 0,6,73:2:0 +X 1598 . C <*> 0 . DP=15;I16=10,5,0,0,514,18282,0,0,900,54000,0,0,244,5240,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,207:9:0 0,12,133:4:0 0,6,68:2:0 +X 1599 . A <*> 0 . DP=14;I16=8,5,0,0,436,15330,0,0,780,46800,0,0,225,4851,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,182:8:0 0,9,103:3:0 0,6,76:2:0 +X 1600 . T <*> 0 . DP=13;I16=8,5,0,0,456,16430,0,0,780,46800,0,0,226,4876,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,193:8:0 0,9,105:3:0 0,6,79:2:0 +X 1601 . C <*> 0 . DP=13;I16=8,4,0,0,431,15861,0,0,720,43200,0,0,208,4554,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,171:7:0 0,9,108:3:0 0,6,78:2:0 +X 1602 . T <*> 0 . DP=13;I16=7,5,0,0,439,16867,0,0,720,43200,0,0,228,4968,0,0;QS=3,0;MQSB=0.95494;MQ0F=0 PL:DP:DV 0,21,179:7:0 0,9,115:3:0 0,6,85:2:0 +X 1603 . G <*> 0 . DP=12;I16=7,5,0,0,455,17407,0,0,720,43200,0,0,230,5034,0,0;QS=3,0;MQSB=0.95494;MQ0F=0 PL:DP:DV 0,21,202:7:0 0,9,111:3:0 0,6,75:2:0 +X 1604 . G <*> 0 . DP=12;I16=7,5,0,0,362,11620,0,0,720,43200,0,0,232,5112,0,0;QS=3,0;MQSB=0.95494;MQ0F=0 PL:DP:DV 0,21,163:7:0 0,9,84:3:0 0,6,66:2:0 +X 1605 . T <*> 0 . DP=12;I16=7,5,0,0,410,14230,0,0,720,43200,0,0,234,5202,0,0;QS=3,0;MQSB=0.95494;MQ0F=0 PL:DP:DV 0,21,190:7:0 0,9,97:3:0 0,6,61:2:0 +X 1606 . G <*> 0 . DP=12;I16=7,4,0,0,370,12738,0,0,660,39600,0,0,211,4679,0,0;QS=3,0;MQSB=0.964642;MQ0F=0 PL:DP:DV 0,18,165:6:0 0,9,91:3:0 0,6,56:2:0 +X 1607 . A <*> 0 . DP=12;I16=7,4,0,0,337,11369,0,0,660,39600,0,0,226,5222,0,0;QS=3,0;MQSB=0.964642;MQ0F=0 PL:DP:DV 0,21,161:7:0 0,6,70:2:0 0,6,55:2:0 +X 1608 . C <*> 0 . DP=12;I16=7,4,0,0,366,12898,0,0,660,39600,0,0,211,4727,0,0;QS=3,0;MQSB=0.964642;MQ0F=0 PL:DP:DV 0,18,141:6:0 0,9,111:3:0 0,6,62:2:0 +X 1609 . C <*> 0 . DP=11;I16=6,5,0,0,365,12889,0,0,660,39600,0,0,237,5393,0,0;QS=3,0;MQSB=0.950952;MQ0F=0 PL:DP:DV 0,18,149:6:0 0,9,110:3:0 0,6,71:2:0 +X 1610 . C <*> 0 . DP=11;I16=5,5,0,0,313,10713,0,0,600,36000,0,0,213,4819,0,0;QS=3,0;MQSB=0.952347;MQ0F=0 PL:DP:DV 0,15,127:5:0 0,9,106:3:0 0,6,57:2:0 +X 1611 . C <*> 0 . DP=11;I16=6,5,0,0,398,14904,0,0,660,39600,0,0,238,5454,0,0;QS=3,0;MQSB=0.950952;MQ0F=0 PL:DP:DV 0,18,180:6:0 0,9,110:3:0 0,6,67:2:0 +X 1612 . T <*> 0 . DP=11;I16=6,5,0,0,409,15421,0,0,660,39600,0,0,238,5472,0,0;QS=3,0;MQSB=0.950952;MQ0F=0 PL:DP:DV 0,18,174:6:0 0,9,107:3:0 0,6,83:2:0 +X 1613 . C <*> 0 . DP=11;I16=6,5,0,0,372,12904,0,0,660,39600,0,0,238,5498,0,0;QS=3,0;MQSB=0.950952;MQ0F=0 PL:DP:DV 0,18,169:6:0 0,9,99:3:0 0,6,63:2:0 +X 1614 . A <*> 0 . DP=11;I16=6,5,0,0,353,12139,0,0,660,39600,0,0,238,5532,0,0;QS=3,0;MQSB=0.950952;MQ0F=0 PL:DP:DV 0,18,147:6:0 0,9,98:3:0 0,6,69:2:0 +X 1615 . C <*> 0 . DP=11;I16=6,5,0,0,366,13080,0,0,660,39600,0,0,238,5574,0,0;QS=3,0;MQSB=0.950952;MQ0F=0 PL:DP:DV 0,18,171:6:0 0,9,105:3:0 0,6,51:2:0 +X 1616 . T <*> 0 . DP=11;I16=6,3,0,0,348,13606,0,0,540,32400,0,0,187,4323,0,0;QS=3,0;MQSB=0.924584;MQ0F=0 PL:DP:DV 0,15,159:5:0 0,9,105:3:0 0,3,42:1:0 +X 1617 . C <*> 0 . DP=12;I16=6,3,0,0,330,12316,0,0,540,32400,0,0,185,4279,0,0;QS=3,0;MQSB=0.924584;MQ0F=0 PL:DP:DV 0,15,146:5:0 0,9,105:3:0 0,3,42:1:0 +X 1618 . A <*> 0 . DP=12;I16=5,6,0,0,385,14199,0,0,629,36841,0,0,244,5636,0,0;QS=3,0;MQSB=0.891517;MQ0F=0 PL:DP:DV 0,18,151:6:0 0,9,93:3:0 0,6,81:2:0 +X 1619 . G <*> 0 . DP=11;I16=5,6,0,0,377,13119,0,0,629,36841,0,0,242,5544,0,0;QS=3,0;MQSB=0.891517;MQ0F=0 PL:DP:DV 0,18,166:6:0 0,9,84:3:0 0,6,67:2:0 +X 1620 . C <*> 0 . DP=11;I16=5,5,0,0,323,10965,0,0,569,33241,0,0,215,4839,0,0;QS=3,0;MQSB=0.857112;MQ0F=0 PL:DP:DV 0,15,142:5:0 0,9,78:3:0 0,6,56:2:0 +X 1621 . C <*> 0 . DP=12;I16=5,7,0,0,363,11779,0,0,689,40441,0,0,263,6021,0,0;QS=3,0;MQSB=0.896474;MQ0F=0 PL:DP:DV 0,21,174:7:0 0,9,80:3:0 0,6,56:2:0 +X 1622 . A <*> 0 . DP=12;I16=5,7,0,0,365,12105,0,0,689,40441,0,0,261,5965,0,0;QS=3,0;MQSB=0.896474;MQ0F=0 PL:DP:DV 0,21,176:7:0 0,9,81:3:0 0,6,52:2:0 +X 1623 . C <*> 0 . DP=12;I16=5,5,0,0,325,10979,0,0,569,33241,0,0,208,4620,0,0;QS=3,0;MQSB=0.857112;MQ0F=0 PL:DP:DV 0,18,155:6:0 0,9,84:3:0 0,3,37:1:0 +X 1624 . C <*> 0 . DP=12;I16=4,6,0,0,336,11718,0,0,569,33241,0,0,211,4799,0,0;QS=3,0;MQSB=0.895781;MQ0F=0 PL:DP:DV 0,18,162:6:0 0,9,88:3:0 0,3,39:1:0 +X 1625 . A <*> 0 . DP=12;I16=4,7,0,0,375,13503,0,0,629,36841,0,0,234,5386,0,0;QS=3,0;MQSB=0.924449;MQ0F=0 PL:DP:DV 0,18,158:6:0 0,9,93:3:0 0,6,80:2:0 +X 1626 . G <*> 0 . DP=12;I16=5,7,0,0,358,11490,0,0,689,40441,0,0,249,5645,0,0;QS=3,0;MQSB=0.896474;MQ0F=0 PL:DP:DV 0,21,158:7:0 0,9,83:3:0 0,6,63:2:0 +X 1627 . A <*> 0 . DP=12;I16=5,7,0,0,363,11609,0,0,689,40441,0,0,246,5590,0,0;QS=3,0;MQSB=0.896474;MQ0F=0 PL:DP:DV 0,21,165:7:0 0,9,75:3:0 0,6,72:2:0 +X 1628 . C <*> 0 . DP=12;I16=5,7,0,0,357,11583,0,0,689,40441,0,0,243,5545,0,0;QS=3,0;MQSB=0.896474;MQ0F=0 PL:DP:DV 0,21,165:7:0 0,9,80:3:0 0,6,57:2:0 +X 1629 . T <*> 0 . DP=13;I16=6,7,0,0,451,16079,0,0,749,44041,0,0,240,5510,0,0;QS=3,0;MQSB=0.899815;MQ0F=0 PL:DP:DV 0,21,187:7:0 0,12,120:4:0 0,6,79:2:0 +X 1630 . T <*> 0 . DP=13;I16=6,7,0,0,403,13323,0,0,749,44041,0,0,237,5435,0,0;QS=3,0;MQSB=0.899815;MQ0F=0 PL:DP:DV 0,21,169:7:0 0,12,111:4:0 0,6,73:2:0 +X 1631 . C <*> 0 . DP=12;I16=6,5,0,0,354,12046,0,0,660,39600,0,0,210,4744,0,0;QS=3,0;MQSB=0.950952;MQ0F=0 PL:DP:DV 0,21,184:7:0 0,6,67:2:0 0,6,61:2:0 +X 1632 . C <*> 0 . DP=13;I16=6,7,0,0,387,12175,0,0,749,44041,0,0,232,5262,0,0;QS=3,0;MQSB=0.899815;MQ0F=0 PL:DP:DV 0,24,188:8:0 0,9,82:3:0 0,6,61:2:0 +X 1633 . A <*> 0 . DP=13;I16=6,7,0,0,404,13272,0,0,749,44041,0,0,230,5166,0,0;QS=3,0;MQSB=0.899815;MQ0F=0 PL:DP:DV 0,24,183:8:0 0,9,86:3:0 0,6,73:2:0 +X 1634 . C <*> 0 . DP=13;I16=6,6,0,0,328,9716,0,0,689,40441,0,0,203,4457,0,0;QS=3,0;MQSB=0.864013;MQ0F=0 PL:DP:DV 0,21,151:7:0 0,9,80:3:0 0,6,59:2:0 +X 1635 . G <*> 0 . DP=14;I16=6,8,0,0,419,12831,0,0,809,47641,0,0,226,5010,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,24,180:8:0 0,12,108:4:0 0,6,59:2:0 +X 1636 . A <*> 0 . DP=14;I16=6,8,0,0,418,13400,0,0,809,47641,0,0,225,4951,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,24,179:8:0 0,12,110:4:0 0,6,66:2:0 +X 1637 . C <*> 0 . DP=14;I16=6,8,0,0,422,13498,0,0,809,47641,0,0,224,4906,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,24,185:8:0 0,12,110:4:0 0,6,60:2:0 +X 1638 . A <*> 0 . DP=17;I16=9,7,0,0,513,17167,0,0,929,54841,0,0,216,4790,0,0;QS=3,0;MQSB=0.892753;MQ0F=0 PL:DP:DV 0,24,191:8:0 0,18,149:6:0 0,6,78:2:0 +X 1639 . G <*> 0 . DP=17;I16=9,8,0,0,552,18844,0,0,989,58441,0,0,223,4765,0,0;QS=3,0;MQSB=0.91051;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,18,150:6:0 0,6,68:2:0 +X 1640 . G <*> 0 . DP=17;I16=8,6,0,0,414,13296,0,0,809,47641,0,0,171,3467,0,0;QS=3,0;MQSB=0.875173;MQ0F=0 PL:DP:DV 0,18,150:6:0 0,18,151:6:0 0,6,51:2:0 +X 1641 . C <*> 0 . DP=18;I16=9,8,0,0,511,16289,0,0,989,58441,0,0,225,4709,0,0;QS=3,0;MQSB=0.91051;MQ0F=0 PL:DP:DV 0,27,188:9:0 0,18,167:6:0 0,6,65:2:0 +X 1642 . T <*> 0 . DP=17;I16=8,7,0,0,519,18513,0,0,869,51241,0,0,217,4613,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,18,170:6:0 0,18,168:6:0 0,9,102:3:0 +X 1643 . C <*> 0 . DP=16;I16=7,9,0,0,508,16910,0,0,929,54841,0,0,255,5361,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,24,193:8:0 0,18,169:6:0 0,6,56:2:0 +X 1644 . C <*> 0 . DP=15;I16=6,9,0,0,514,18056,0,0,869,51241,0,0,259,5401,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,21,209:7:0 0,18,165:6:0 0,6,54:2:0 +X 1645 . A <*> 0 . DP=15;I16=6,9,0,0,520,18852,0,0,869,51241,0,0,263,5457,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,21,213:7:0 0,18,173:6:0 0,6,49:2:0 +X 1646 . G <*> 0 . DP=15;I16=6,7,0,0,440,15526,0,0,780,46800,0,0,217,4279,0,0;QS=3,0;MQSB=0.961166;MQ0F=0 PL:DP:DV 0,18,185:6:0 0,15,148:5:0 0,6,48:2:0 +X 1647 . C <*> 0 . DP=15;I16=6,9,0,0,433,13883,0,0,869,51241,0,0,271,5617,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,21,190:7:0 0,18,139:6:0 0,6,35:2:0 +X 1648 . C <*> 0 . DP=15;I16=6,9,0,0,495,16965,0,0,869,51241,0,0,275,5721,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,21,203:7:0 0,18,159:6:0 0,6,44:2:0 +X 1649 . T <*> 0 . DP=15;I16=6,9,0,0,516,18122,0,0,869,51241,0,0,279,5841,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,21,187:7:0 0,18,182:6:0 0,6,56:2:0 +X 1650 . C <*> 0 . DP=15;I16=6,7,0,0,405,13551,0,0,749,44041,0,0,240,5028,0,0;QS=3,0;MQSB=0.899815;MQ0F=0 PL:DP:DV 0,18,161:6:0 0,18,169:6:0 0,3,13:1:0 +X 1651 . G <*> 0 . DP=17;I16=5,9,0,0,424,13328,0,0,778,44882,0,0,249,5335,0,0;QS=3,0;MQSB=0.965069;MQ0F=0 PL:DP:DV 0,18,150:6:0 0,15,128:5:0 0,9,86:3:0 +X 1652 . G <*> 0 . DP=18;I16=7,9,0,0,532,18602,0,0,898,52082,0,0,267,5673,0,0;QS=3,0;MQSB=0.994413;MQ0F=0 PL:DP:DV 0,24,212:8:0 0,18,168:6:0 0,6,54:2:0 +X 1653 . C <*> 0 . DP=18;I16=8,10,0,0,581,19565,0,0,1018,59282,0,0,300,6490,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,24,208:8:0 0,21,175:7:0 0,9,82:3:0 +X 1654 . A T,<*> 0 . DP=18;I16=8,9,0,1,516,16718,15,225,958,55682,60,3600,285,6219,22,484;QS=2.93213,0.0678733,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.99606;BQB=1;MQ0F=0 PL:DP:DV 0,9,155,21,158,162:8:1 0,21,179,21,179,179:7:0 0,9,78,9,78,78:3:0 +X 1655 . C <*> 0 . DP=18;I16=8,10,0,0,565,19017,0,0,1018,59282,0,0,313,6887,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,24,198:8:0 0,21,180:7:0 0,9,79:3:0 +X 1656 . C <*> 0 . DP=19;I16=9,9,0,0,557,18013,0,0,1018,59282,0,0,295,6515,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,202:8:0 0,21,165:7:0 0,9,80:3:0 +X 1657 . T A,<*> 0 . DP=18;I16=8,9,0,1,580,20362,15,225,989,58441,29,841,301,6641,25,625;QS=2.93243,0.0675676,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.99606;BQB=1;MQ0F=0 PL:DP:DV 0,24,206,24,206,206:8:0 0,6,158,18,161,165:7:1 0,9,85,9,85,85:3:0 +X 1658 . T <*> 0 . DP=19;I16=8,10,0,0,573,19127,0,0,1018,59282,0,0,332,7412,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,24,187:8:0 0,21,189:7:0 0,9,91:3:0 +X 1659 . C <*> 0 . DP=20;I16=8,10,0,0,609,21517,0,0,1049,62041,0,0,338,7578,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,24,219:8:0 0,21,189:7:0 0,9,80:3:0 +X 1660 . A <*> 0 . DP=21;I16=8,11,0,0,641,23219,0,0,1078,62882,0,0,385,8901,0,0;QS=3,0;MQSB=0.992359;MQ0F=0 PL:DP:DV 0,21,172:7:0 0,24,219:8:0 0,12,127:4:0 +X 1661 . G <*> 0 . DP=21;I16=7,13,0,0,639,21739,0,0,1107,63723,0,0,412,9598,0,0;QS=3,0;MQSB=0.999215;MQ0F=0 PL:DP:DV 0,24,209:8:0 0,24,193:8:0 0,12,98:4:0 +X 1662 . C <*> 0 . DP=21;I16=8,12,0,0,641,21423,0,0,1107,63723,0,0,407,9465,0,0;QS=3,0;MQSB=0.988166;MQ0F=0 PL:DP:DV 0,21,192:7:0 0,27,211:9:0 0,12,100:4:0 +X 1663 . C <*> 0 . DP=20;I16=7,11,0,0,577,19507,0,0,1018,59282,0,0,394,9204,0,0;QS=3,0;MQSB=0.983729;MQ0F=0 PL:DP:DV 0,21,178:7:0 0,21,192:7:0 0,12,101:4:0 +X 1664 . A C,<*> 0 . DP=20;I16=6,10,0,1,530,17982,13,169,898,52082,29,841,358,8422,25,625;QS=2.93953,0.0604651,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.998738;BQB=1;MQ0F=0 PL:DP:DV 0,18,167,18,167,167:6:0 0,7,154,18,157,159:7:1 0,12,109,12,109,109:4:0 +X 1665 . T C,<*> 0 . DP=20;I16=7,11,1,1,592,20170,58,1924,1018,59282,89,4441,396,9188,39,821;QS=2.5913,0.408696,0;VDB=0.1;SGB=0.346553;RPB=0.222222;MQB=0.611111;MQSB=0.988166;BQB=0.944444;MQ0F=0 PL:DP:DV 0,21,185,21,185,185:7:0 0,27,222,27,222,222:9:0 35,0,51,41,57,90:4:2 +X 1666 . G <*> 0 . DP=20;I16=8,12,0,0,614,19760,0,0,1107,63723,0,0,435,9947,0,0;QS=3,0;MQSB=0.988166;MQ0F=0 PL:DP:DV 0,21,173:7:0 0,27,206:9:0 0,12,111:4:0 +X 1667 . G <*> 0 . DP=20;I16=8,11,0,0,617,21033,0,0,1078,62882,0,0,410,9276,0,0;QS=3,0;MQSB=0.992359;MQ0F=0 PL:DP:DV 0,21,183:7:0 0,24,195:8:0 0,12,115:4:0 +X 1668 . A <*> 0 . DP=20;I16=7,10,0,0,570,19908,0,0,958,55682,0,0,369,8365,0,0;QS=3,0;MQSB=0.989343;MQ0F=0 PL:DP:DV 0,18,158:6:0 0,21,186:7:0 0,12,124:4:0 +X 1669 . C <*> 0 . DP=20;I16=8,12,0,0,640,21336,0,0,1107,63723,0,0,435,9857,0,0;QS=3,0;MQSB=0.988166;MQ0F=0 PL:DP:DV 0,21,172:7:0 0,27,216:9:0 0,12,115:4:0 +X 1670 . A <*> 0 . DP=23;I16=9,13,0,0,765,27363,0,0,1258,73682,0,0,410,9234,0,0;QS=3,0;MQSB=0.991121;MQ0F=0 PL:DP:DV 0,27,215:9:0 0,27,233:9:0 0,12,129:4:0 +X 1671 . G <*> 0 . DP=23;I16=9,13,0,0,703,23631,0,0,1258,73682,0,0,412,9206,0,0;QS=3,0;MQSB=0.991121;MQ0F=0 PL:DP:DV 0,27,214:9:0 0,27,210:9:0 0,12,106:4:0 +X 1672 . T <*> 0 . DP=23;I16=9,13,0,0,724,24700,0,0,1258,73682,0,0,414,9202,0,0;QS=3,0;MQSB=0.991121;MQ0F=0 PL:DP:DV 0,27,203:9:0 0,27,232:9:0 0,12,111:4:0 +X 1673 . T <*> 0 . DP=25;I16=8,13,0,0,719,25183,0,0,1198,70082,0,0,372,8248,0,0;QS=3,0;MQSB=0.983744;MQ0F=0 PL:DP:DV 0,27,221:9:0 0,24,212:8:0 0,12,112:4:0 +X 1674 . C <*> 0 . DP=25;I16=8,14,0,0,755,26561,0,0,1289,76441,0,0,389,8417,0,0;QS=3,0;MQSB=0.892142;MQ0F=0 PL:DP:DV 0,33,244:11:0 0,21,206:7:0 0,12,96:4:0 +X 1675 . C <*> 0 . DP=25;I16=9,15,0,0,705,22355,0,0,1347,78123,0,0,447,9897,0,0;QS=3,0;MQSB=0.996008;MQ0F=0 PL:DP:DV 0,33,222:11:0 0,30,212:10:0 0,9,65:3:0 +X 1676 . G <*> 0 . DP=25;I16=6,15,0,0,660,21708,0,0,1167,67323,0,0,383,8265,0,0;QS=3,0;MQSB=0.993205;MQ0F=0 PL:DP:DV 0,33,222:11:0 0,21,170:7:0 0,9,96:3:0 +X 1677 . C <*> 0 . DP=25;I16=9,13,0,0,681,22869,0,0,1289,76441,0,0,394,8510,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,33,225:11:0 0,24,198:8:0 0,9,74:3:0 +X 1678 . C <*> 0 . DP=25;I16=9,15,0,0,775,26785,0,0,1347,78123,0,0,438,9496,0,0;QS=3,0;MQSB=0.996008;MQ0F=0 PL:DP:DV 0,33,235:11:0 0,30,231:10:0 0,9,83:3:0 +X 1679 . A <*> 0 . DP=25;I16=8,15,0,0,762,27552,0,0,1287,74523,0,0,412,8858,0,0;QS=3,0;MQSB=0.999479;MQ0F=0 PL:DP:DV 0,33,235:11:0 0,27,219:9:0 0,9,106:3:0 +X 1680 . G <*> 0 . DP=26;I16=9,17,0,0,843,29213,0,0,1467,85323,0,0,459,10021,0,0;QS=3,0;MQSB=0.999637;MQ0F=0 PL:DP:DV 0,33,253:11:0 0,33,232:11:0 0,12,108:4:0 +X 1681 . C <*> 0 . DP=26;I16=8,15,0,0,681,21293,0,0,1318,77282,0,0,407,8999,0,0;QS=3,0;MQSB=0.974802;MQ0F=0 PL:DP:DV 0,33,223:11:0 0,27,191:9:0 0,9,69:3:0 +X 1682 . G <*> 0 . DP=25;I16=9,16,0,0,728,22560,0,0,1407,81723,0,0,455,9877,0,0;QS=3,0;MQSB=0.998399;MQ0F=0 PL:DP:DV 0,30,222:10:0 0,33,208:11:0 0,12,98:4:0 +X 1683 . T <*> 0 . DP=25;I16=8,15,0,0,807,29159,0,0,1287,74523,0,0,403,8567,0,0;QS=3,0;MQSB=0.999479;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,30,235:10:0 0,9,91:3:0 +X 1684 . T <*> 0 . DP=25;I16=8,15,0,0,802,28774,0,0,1318,77282,0,0,438,9612,0,0;QS=3,0;MQSB=0.974802;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,30,237:10:0 0,12,107:4:0 +X 1685 . G <*> 0 . DP=24;I16=8,14,0,0,759,27319,0,0,1258,73682,0,0,413,8999,0,0;QS=3,0;MQSB=0.979255;MQ0F=0 PL:DP:DV 0,24,216:8:0 0,30,242:10:0 0,12,110:4:0 +X 1686 . C <*> 0 . DP=24;I16=8,15,0,0,793,28073,0,0,1318,77282,0,0,438,9656,0,0;QS=3,0;MQSB=0.974802;MQ0F=0 PL:DP:DV 0,27,225:9:0 0,30,241:10:0 0,12,103:4:0 +X 1687 . C <*> 0 . DP=24;I16=7,14,0,0,741,26765,0,0,1198,70082,0,0,388,8458,0,0;QS=3,0;MQSB=0.966484;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,27,229:9:0 0,12,106:4:0 +X 1688 . C <*> 0 . DP=24;I16=8,15,0,0,794,28736,0,0,1318,77282,0,0,431,9605,0,0;QS=3,0;MQSB=0.974802;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,30,221:10:0 0,12,120:4:0 +X 1689 . T A,<*> 0 . DP=24;I16=8,15,0,1,805,29443,33,1089,1287,74523,60,3600,421,9311,25,625;QS=2.74419,0.255814,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,27,224,27,224,224:9:0 0,33,255,33,255,255:11:0 21,0,79,30,82,106:4:1 +X 1690 . C <*> 0 . DP=24;I16=8,16,0,0,864,32420,0,0,1347,78123,0,0,445,10033,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,242:9:0 0,33,255:11:0 0,12,95:4:0 +X 1691 . T <*> 0 . DP=22;I16=7,14,0,0,734,27150,0,0,1167,67323,0,0,421,9525,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,225:9:0 0,30,242:10:0 0,6,57:2:0 +X 1692 . G <*> 0 . DP=22;I16=7,13,0,0,678,24110,0,0,1107,63723,0,0,400,9176,0,0;QS=3,0;MQSB=0.999215;MQ0F=0 PL:DP:DV 0,24,218:8:0 0,30,218:10:0 0,6,61:2:0 +X 1693 . T <*> 0 . DP=24;I16=10,13,0,0,795,28363,0,0,1318,77282,0,0,444,10422,0,0;QS=3,0;MQSB=0.995682;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,30,235:10:0 0,12,104:4:0 +X 1694 . T <*> 0 . DP=24;I16=10,13,0,0,771,26775,0,0,1318,77282,0,0,448,10602,0,0;QS=3,0;MQSB=0.995682;MQ0F=0 PL:DP:DV 0,27,221:9:0 0,30,232:10:0 0,12,114:4:0 +X 1695 . C <*> 0 . DP=24;I16=10,14,0,0,811,28517,0,0,1347,78123,0,0,454,10806,0,0;QS=3,0;MQSB=0.98469;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,33,239:11:0 0,12,121:4:0 +X 1696 . T <*> 0 . DP=23;I16=10,13,0,0,825,30819,0,0,1287,74523,0,0,455,10869,0,0;QS=3,0;MQSB=0.976718;MQ0F=0 PL:DP:DV 0,24,219:8:0 0,33,255:11:0 0,12,108:4:0 +X 1697 . G <*> 0 . DP=23;I16=10,13,0,0,767,26757,0,0,1287,74523,0,0,455,10897,0,0;QS=3,0;MQSB=0.976718;MQ0F=0 PL:DP:DV 0,24,208:8:0 0,33,246:11:0 0,12,112:4:0 +X 1698 . C A,<*> 0 . DP=21;I16=10,10,0,1,726,27088,27,729,1169,69241,29,841,451,10903,6,36;QS=2.91148,0.0885246,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.99938;BQB=1;MQ0F=0 PL:DP:DV 0,24,229,24,229,229:8:0 0,0,190,24,193,207:9:1 0,12,111,12,111,111:4:0 +X 1699 . T <*> 0 . DP=21;I16=9,10,0,0,698,25826,0,0,1078,62882,0,0,408,9692,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,21,203:7:0 0,24,219:8:0 0,12,115:4:0 +X 1700 . G <*> 0 . DP=20;I16=9,10,0,0,696,25850,0,0,1078,62882,0,0,409,9705,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,21,216:7:0 0,24,215:8:0 0,12,110:4:0 +X 1701 . T <*> 0 . DP=20;I16=9,11,0,0,711,25539,0,0,1138,66482,0,0,435,10353,0,0;QS=3,0;MQSB=0.997118;MQ0F=0 PL:DP:DV 0,24,207:8:0 0,24,210:8:0 0,12,125:4:0 +X 1702 . T <*> 0 . DP=20;I16=8,11,0,0,671,24367,0,0,1078,62882,0,0,410,9712,0,0;QS=3,0;MQSB=0.992359;MQ0F=0 PL:DP:DV 0,24,214:8:0 0,21,193:7:0 0,12,115:4:0 +X 1703 . T <*> 0 . DP=20;I16=9,10,0,0,648,22696,0,0,1078,62882,0,0,410,9708,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,21,197:7:0 0,24,195:8:0 0,12,114:4:0 +X 1704 . T <*> 0 . DP=20;I16=10,10,0,0,711,25771,0,0,1169,69241,0,0,435,10341,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,24,208:8:0 0,21,208:7:0 0,15,128:5:0 +X 1705 . C <*> 0 . DP=20;I16=10,10,0,0,744,28388,0,0,1169,69241,0,0,436,10312,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,24,232:8:0 0,21,213:7:0 0,15,120:5:0 +X 1706 . T <*> 0 . DP=20;I16=10,10,0,0,775,30329,0,0,1169,69241,0,0,436,10246,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,21,219:7:0 0,15,145:5:0 +X 1707 . C <*> 0 . DP=21;I16=9,11,0,0,724,26998,0,0,1169,69241,0,0,410,9518,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,27,235:9:0 0,18,180:6:0 0,15,134:5:0 +X 1708 . T <*> 0 . DP=21;I16=9,12,0,0,740,27282,0,0,1229,72841,0,0,410,9430,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,30,229:10:0 0,18,187:6:0 0,15,132:5:0 +X 1709 . A <*> 0 . DP=21;I16=9,11,0,0,675,23509,0,0,1169,69241,0,0,386,8734,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,27,210:9:0 0,18,166:6:0 0,15,131:5:0 +X 1710 . C <*> 0 . DP=22;I16=9,13,0,0,755,26817,0,0,1289,76441,0,0,412,9306,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,33,236:11:0 0,18,181:6:0 0,15,128:5:0 +X 1711 . C <*> 0 . DP=22;I16=9,13,0,0,786,28790,0,0,1289,76441,0,0,413,9223,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,33,250:11:0 0,18,169:6:0 0,15,138:5:0 +X 1712 . A <*> 0 . DP=22;I16=9,13,0,0,824,31342,0,0,1289,76441,0,0,414,9162,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,33,252:11:0 0,18,198:6:0 0,15,136:5:0 +X 1713 . G <*> 0 . DP=23;I16=8,14,0,0,823,31285,0,0,1289,76441,0,0,405,8993,0,0;QS=3,0;MQSB=0.892142;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,189:6:0 0,12,118:4:0 +X 1714 . A <*> 0 . DP=23;I16=9,13,0,0,763,27439,0,0,1289,76441,0,0,402,8818,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,36,234:12:0 0,18,190:6:0 0,12,101:4:0 +X 1715 . A <*> 0 . DP=23;I16=9,14,0,0,900,35416,0,0,1349,80041,0,0,414,8878,0,0;QS=3,0;MQSB=0.907354;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,206:6:0 0,15,145:5:0 +X 1716 . G <*> 0 . DP=23;I16=9,14,0,0,844,31500,0,0,1349,80041,0,0,414,8822,0,0;QS=3,0;MQSB=0.907354;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,188:6:0 0,15,129:5:0 +X 1717 . T <*> 0 . DP=24;I16=9,15,0,0,854,30878,0,0,1409,83641,0,0,414,8794,0,0;QS=3,0;MQSB=0.904837;MQ0F=0 PL:DP:DV 0,39,253:13:0 0,18,185:6:0 0,15,122:5:0 +X 1718 . G <*> 0 . DP=24;I16=9,14,0,0,806,29332,0,0,1349,80041,0,0,390,8170,0,0;QS=3,0;MQSB=0.907354;MQ0F=0 PL:DP:DV 0,36,249:12:0 0,18,188:6:0 0,15,124:5:0 +X 1719 . C <*> 0 . DP=26;I16=11,14,0,0,857,30717,0,0,1469,87241,0,0,407,8675,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,173:6:0 0,12,98:4:0 +X 1720 . C <*> 0 . DP=26;I16=11,14,0,0,898,33274,0,0,1469,87241,0,0,409,8645,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,166:6:0 0,12,99:4:0 +X 1721 . C <*> 0 . DP=26;I16=10,14,0,0,846,30642,0,0,1409,83641,0,0,388,8258,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,187:6:0 0,12,119:4:0 +X 1722 . T <*> 0 . DP=25;I16=11,13,0,0,876,33054,0,0,1409,83641,0,0,406,8540,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,174:5:0 0,15,123:5:0 +X 1723 . T <*> 0 . DP=25;I16=11,14,0,0,835,28861,0,0,1469,87241,0,0,420,8728,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,167:5:0 0,15,130:5:0 +X 1724 . C <*> 0 . DP=25;I16=11,14,0,0,903,33735,0,0,1469,87241,0,0,422,8800,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,164:5:0 0,15,139:5:0 +X 1725 . C G,<*> 0 . DP=25;I16=11,13,0,1,835,29699,25,625,1409,83641,60,3600,406,8576,18,324;QS=2.95164,0.0483559,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.929204;BQB=1;MQ0F=0 PL:DP:DV 0,20,255,42,255,255:15:1 0,15,153,15,153,153:5:0 0,15,132,15,132,132:5:0 +X 1726 . C <*> 0 . DP=25;I16=11,14,0,0,932,35588,0,0,1469,87241,0,0,426,9028,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,165:5:0 0,15,122:5:0 +X 1727 . T <*> 0 . DP=25;I16=10,14,0,0,862,32080,0,0,1409,83641,0,0,404,8556,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,167:5:0 0,12,120:4:0 +X 1728 . C <*> 0 . DP=25;I16=11,14,0,0,915,33845,0,0,1469,87241,0,0,429,9173,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,156:5:0 0,15,144:5:0 +X 1729 . C <*> 0 . DP=25;I16=10,14,0,0,919,35797,0,0,1409,83641,0,0,406,8668,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,142:5:0 0,12,128:4:0 +X 1730 . T <*> 0 . DP=24;I16=10,14,0,0,849,30711,0,0,1409,83641,0,0,433,9393,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,138:4:0 0,15,148:5:0 +X 1731 . C <*> 0 . DP=24;I16=10,14,0,0,907,34875,0,0,1409,83641,0,0,434,9472,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,123:4:0 0,15,140:5:0 +X 1732 . A <*> 0 . DP=24;I16=11,13,0,0,816,28582,0,0,1409,83641,0,0,436,9580,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,123:4:0 0,15,143:5:0 +X 1733 . C <*> 0 . DP=25;I16=12,13,0,0,869,31451,0,0,1469,87241,0,0,438,9666,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,116:4:0 0,15,136:5:0 +X 1734 . C <*> 0 . DP=25;I16=12,13,0,0,926,35482,0,0,1469,87241,0,0,440,9730,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,122:4:0 0,15,141:5:0 +X 1735 . T <*> 0 . DP=26;I16=13,13,0,0,935,35169,0,0,1529,90841,0,0,442,9822,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,112:4:0 0,15,148:5:0 +X 1736 . G <*> 0 . DP=25;I16=11,11,0,0,829,31469,0,0,1289,76441,0,0,380,8416,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,72:2:0 0,12,118:4:0 +X 1737 . A <*> 0 . DP=25;I16=12,12,0,0,842,30606,0,0,1409,83641,0,0,422,9312,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,76:2:0 0,15,131:5:0 +X 1738 . C <*> 0 . DP=24;I16=12,12,0,0,835,30251,0,0,1409,83641,0,0,450,10010,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,78:3:0 0,15,130:5:0 +X 1739 . C <*> 0 . DP=23;I16=10,12,0,0,831,32123,0,0,1289,76441,0,0,428,9432,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,55:2:0 0,12,135:4:0 +X 1740 . A <*> 0 . DP=23;I16=11,12,0,0,774,27126,0,0,1349,80041,0,0,456,10126,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,56:2:0 0,15,139:5:0 +X 1741 . C <*> 0 . DP=23;I16=11,12,0,0,850,32314,0,0,1349,80041,0,0,459,10217,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,70:2:0 0,15,136:5:0 +X 1742 . T <*> 0 . DP=23;I16=11,12,0,0,866,33204,0,0,1349,80041,0,0,462,10330,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,72:2:0 0,15,144:5:0 +X 1743 . C <*> 0 . DP=23;I16=11,12,0,0,894,35176,0,0,1349,80041,0,0,464,10414,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,74:2:0 0,15,138:5:0 +X 1744 . T <*> 0 . DP=23;I16=11,11,0,0,857,33579,0,0,1289,76441,0,0,459,10469,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,80:2:0 0,15,156:5:0 +X 1745 . G <*> 0 . DP=23;I16=11,12,0,0,882,34572,0,0,1349,80041,0,0,464,10442,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,78:2:0 0,15,142:5:0 +X 1746 . G <*> 0 . DP=24;I16=12,11,0,0,836,31102,0,0,1349,80041,0,0,456,10312,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,69:2:0 0,18,151:6:0 +X 1747 . G <*> 0 . DP=24;I16=12,11,0,0,839,31729,0,0,1349,80041,0,0,455,10239,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,75:2:0 0,18,154:6:0 +X 1748 . G <*> 0 . DP=24;I16=11,12,0,0,843,31857,0,0,1349,80041,0,0,434,9664,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,42:1:0 0,18,154:6:0 +X 1749 . A <*> 0 . DP=25;I16=13,11,0,0,864,31748,0,0,1409,83641,0,0,451,10063,0,0;QS=3,0;MQSB=0.950498;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,72:2:0 0,21,172:7:0 +X 1750 . A <*> 0 . DP=25;I16=13,12,0,0,905,33667,0,0,1469,87241,0,0,451,10013,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,56:2:0 0,21,187:7:0 +X 1751 . A <*> 0 . DP=25;I16=13,12,0,0,908,33658,0,0,1469,87241,0,0,449,9987,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,67:2:0 0,21,183:7:0 +X 1752 . T <*> 0 . DP=23;I16=12,11,0,0,838,31088,0,0,1380,82800,0,0,449,9987,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,71:2:0 0,18,170:6:0 +X 1753 . C <*> 0 . DP=23;I16=12,11,0,0,869,33595,0,0,1380,82800,0,0,448,9960,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,77:2:0 0,18,163:6:0 +X 1754 . C <*> 0 . DP=23;I16=11,11,0,0,830,31628,0,0,1320,79200,0,0,431,9699,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,3,42:1:0 0,18,163:6:0 +X 1755 . C <*> 0 . DP=23;I16=12,11,0,0,856,33082,0,0,1380,82800,0,0,446,9972,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,61:2:0 0,18,165:6:0 +X 1756 . T <*> 0 . DP=22;I16=11,11,0,0,858,33720,0,0,1320,79200,0,0,445,9961,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,77:2:0 0,18,179:6:0 +X 1757 . C <*> 0 . DP=22;I16=11,11,0,0,869,34651,0,0,1320,79200,0,0,444,9972,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,78:2:0 0,18,176:6:0 +X 1758 . A <*> 0 . DP=22;I16=11,11,0,0,865,34205,0,0,1320,79200,0,0,442,9954,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,81:2:0 0,18,177:6:0 +X 1759 . G <*> 0 . DP=22;I16=11,11,0,0,833,31965,0,0,1320,79200,0,0,439,9905,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,77:2:0 0,18,159:6:0 +X 1760 . C <*> 0 . DP=22;I16=11,11,0,0,849,33441,0,0,1320,79200,0,0,436,9874,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,79:2:0 0,18,159:6:0 +X 1761 . A <*> 0 . DP=22;I16=11,11,0,0,730,25766,0,0,1320,79200,0,0,432,9810,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,75:2:0 0,18,153:6:0 +X 1762 . C <*> 0 . DP=21;I16=11,10,0,0,767,28667,0,0,1260,75600,0,0,429,9761,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,76:2:0 0,18,160:6:0 +X 1763 . C <*> 0 . DP=21;I16=11,10,0,0,789,30115,0,0,1260,75600,0,0,426,9726,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,72:2:0 0,18,162:6:0 +X 1764 . C <*> 0 . DP=21;I16=11,10,0,0,821,32443,0,0,1260,75600,0,0,423,9705,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,72:2:0 0,18,167:6:0 +X 1765 . T <*> 0 . DP=21;I16=11,10,0,0,814,31746,0,0,1260,75600,0,0,420,9698,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,83:2:0 0,18,179:6:0 +X 1766 . C <*> 0 . DP=21;I16=11,10,0,0,796,30564,0,0,1260,75600,0,0,417,9705,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,71:2:0 0,18,162:6:0 +X 1767 . C <*> 0 . DP=21;I16=11,10,0,0,779,29559,0,0,1260,75600,0,0,414,9726,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,73:2:0 0,18,163:6:0 +X 1768 . C <*> 0 . DP=21;I16=11,10,0,0,798,30670,0,0,1260,75600,0,0,411,9761,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,68:2:0 0,18,160:6:0 +X 1769 . T <*> 0 . DP=21;I16=11,10,0,0,819,32179,0,0,1260,75600,0,0,406,9712,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,77:2:0 0,18,184:6:0 +X 1770 . G <*> 0 . DP=19;I16=11,8,0,0,699,26453,0,0,1140,68400,0,0,403,9679,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,68:2:0 0,18,158:6:0 +X 1771 . A <*> 0 . DP=18;I16=10,8,0,0,707,27853,0,0,1080,64800,0,0,401,9659,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,42:1:0 0,18,177:6:0 +X 1772 . G <*> 0 . DP=18;I16=10,8,0,0,669,25513,0,0,1080,64800,0,0,398,9600,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,38:1:0 0,18,159:6:0 +X 1773 . C <*> 0 . DP=17;I16=10,7,0,0,675,26897,0,0,1020,61200,0,0,396,9550,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,3,39:1:0 0,18,172:6:0 +X 1774 . A <*> 0 . DP=17;I16=10,7,0,0,653,25153,0,0,1020,61200,0,0,394,9508,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,3,39:1:0 0,18,172:6:0 +X 1775 . T <*> 0 . DP=17;I16=10,7,0,0,605,22253,0,0,1020,61200,0,0,391,9423,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,3,38:1:0 0,18,156:6:0 +X 1776 . A <*> 0 . DP=17;I16=10,7,0,0,610,22124,0,0,1020,61200,0,0,388,9344,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,254:10:0 0,3,35:1:0 0,18,166:6:0 +X 1777 . C <*> 0 . DP=18;I16=11,7,0,0,661,24975,0,0,1080,64800,0,0,385,9271,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,35:1:0 0,18,158:6:0 +X 1778 . C <*> 0 . DP=18;I16=11,7,0,0,680,25970,0,0,1080,64800,0,0,383,9205,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,31:1:0 0,18,172:6:0 +X 1779 . C <*> 0 . DP=18;I16=11,7,0,0,703,27663,0,0,1080,64800,0,0,381,9147,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,34:1:0 0,18,174:6:0 +X 1780 . T <*> 0 . DP=18;I16=11,7,0,0,672,26000,0,0,1080,64800,0,0,378,9048,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,33:1:0 0,18,177:6:0 +X 1781 . A <*> 0 . DP=19;I16=10,6,0,0,579,21377,0,0,960,57600,0,0,328,7804,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,0,0:0:0 0,15,160:5:0 +X 1782 . C <*> 0 . DP=20;I16=11,9,0,0,715,26603,0,0,1200,72000,0,0,382,8892,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,47:2:0 0,18,156:6:0 +X 1783 . T <*> 0 . DP=20;I16=11,9,0,0,755,29057,0,0,1200,72000,0,0,381,8743,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,68:2:0 0,18,184:6:0 +X 1784 . C <*> 0 . DP=20;I16=10,9,0,0,723,28017,0,0,1140,68400,0,0,360,8212,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,62:2:0 0,15,151:5:0 +X 1785 . T <*> 0 . DP=20;I16=10,10,0,0,766,29878,0,0,1200,72000,0,0,359,8089,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,66:2:0 0,15,168:5:0 +X 1786 . G <*> 0 . DP=22;I16=11,11,0,0,841,32323,0,0,1320,79200,0,0,359,7985,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,68:2:0 0,15,158:5:0 +X 1787 . G <*> 0 . DP=22;I16=11,11,0,0,806,30294,0,0,1320,79200,0,0,361,7903,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,68:2:0 0,15,148:5:0 +X 1788 . C <*> 0 . DP=22;I16=11,11,0,0,858,33674,0,0,1320,79200,0,0,362,7796,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,67:2:0 0,15,158:5:0 +X 1789 . A <*> 0 . DP=23;I16=11,12,0,0,797,28705,0,0,1380,82800,0,0,363,7715,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,69:2:0 0,15,157:5:0 +X 1790 . C <*> 0 . DP=23;I16=11,12,0,0,852,31816,0,0,1380,82800,0,0,365,7661,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,63:2:0 0,15,153:5:0 +X 1791 . A <*> 0 . DP=23;I16=11,12,0,0,830,30484,0,0,1380,82800,0,0,367,7635,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,61:2:0 0,15,155:5:0 +X 1792 . A <*> 0 . DP=23;I16=11,12,0,0,862,32760,0,0,1380,82800,0,0,368,7588,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,67:2:0 0,15,161:5:0 +X 1793 . G <*> 0 . DP=23;I16=11,12,0,0,813,29603,0,0,1380,82800,0,0,369,7571,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,61:2:0 0,15,126:5:0 +X 1794 . C <*> 0 . DP=21;I16=9,12,0,0,736,26472,0,0,1260,75600,0,0,370,7484,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,48:2:0 0,9,96:3:0 +X 1795 . C <*> 0 . DP=21;I16=9,12,0,0,763,28807,0,0,1260,75600,0,0,371,7427,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,45:2:0 0,9,100:3:0 +X 1796 . C <*> 0 . DP=21;I16=9,12,0,0,782,29718,0,0,1260,75600,0,0,372,7400,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,52:2:0 0,9,102:3:0 +X 1797 . A <*> 0 . DP=21;I16=9,12,0,0,704,25190,0,0,1260,75600,0,0,373,7403,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,59:2:0 0,9,92:3:0 +X 1798 . C <*> 0 . DP=21;I16=9,12,0,0,759,28119,0,0,1260,75600,0,0,374,7436,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,49:2:0 0,9,99:3:0 +X 1799 . C <*> 0 . DP=22;I16=9,13,0,0,796,29520,0,0,1320,79200,0,0,375,7499,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,56:2:0 0,12,131:4:0 +X 1800 . C <*> 0 . DP=22;I16=9,13,0,0,866,34352,0,0,1320,79200,0,0,376,7542,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,63:2:0 0,12,138:4:0 +X 1801 . T <*> 0 . DP=22;I16=9,13,0,0,838,32282,0,0,1320,79200,0,0,377,7615,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,63:2:0 0,12,150:4:0 +X 1802 . G <*> 0 . DP=22;I16=9,13,0,0,844,32894,0,0,1320,79200,0,0,378,7718,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,60:2:0 0,12,137:4:0 +X 1803 . C <*> 0 . DP=22;I16=9,13,0,0,837,32691,0,0,1320,79200,0,0,377,7751,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,60:2:0 0,12,143:4:0 +X 1804 . A <*> 0 . DP=23;I16=9,14,0,0,793,28517,0,0,1380,82800,0,0,376,7814,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,54:2:0 0,12,144:4:0 +X 1805 . A <*> 0 . DP=23;I16=9,14,0,0,810,29148,0,0,1380,82800,0,0,376,7908,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,67:2:0 0,12,138:4:0 +X 1806 . A <*> 0 . DP=23;I16=9,14,0,0,816,29932,0,0,1380,82800,0,0,376,8034,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,61:2:0 0,12,139:4:0 +X 1807 . G <*> 0 . DP=22;I16=9,13,0,0,837,32299,0,0,1320,79200,0,0,375,8091,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,67:2:0 0,12,142:4:0 +X 1808 . C <*> 0 . DP=21;I16=9,11,0,0,705,25519,0,0,1200,72000,0,0,354,7716,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,53:2:0 0,12,140:4:0 +X 1809 . C <*> 0 . DP=22;I16=10,12,0,0,789,29123,0,0,1320,79200,0,0,371,8091,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,55:2:0 0,12,143:4:0 +X 1810 . C <*> 0 . DP=21;I16=10,11,0,0,754,27902,0,0,1260,75600,0,0,370,8084,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,51:2:0 0,12,145:4:0 +X 1811 . C <*> 0 . DP=22;I16=11,11,0,0,837,32353,0,0,1320,79200,0,0,368,8056,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,61:2:0 0,12,146:4:0 +X 1812 . T <*> 0 . DP=22;I16=11,11,0,0,830,31782,0,0,1320,79200,0,0,365,7955,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,60:2:0 0,12,151:4:0 +X 1813 . G <*> 0 . DP=21;I16=11,10,0,0,789,29971,0,0,1260,75600,0,0,363,7879,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,63:2:0 0,12,135:4:0 +X 1814 . A <*> 0 . DP=21;I16=11,10,0,0,780,29356,0,0,1260,75600,0,0,361,7827,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,63:2:0 0,12,148:4:0 +X 1815 . G <*> 0 . DP=21;I16=11,10,0,0,742,27064,0,0,1260,75600,0,0,358,7748,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,56:2:0 0,12,135:4:0 +X 1816 . G <*> 0 . DP=21;I16=11,10,0,0,702,24670,0,0,1260,75600,0,0,355,7691,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,49:2:0 0,12,124:4:0 +X 1817 . C <*> 0 . DP=20;I16=11,9,0,0,701,25263,0,0,1200,72000,0,0,353,7655,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,58:2:0 0,12,134:4:0 +X 1818 . C <*> 0 . DP=20;I16=11,8,0,0,665,23987,0,0,1140,68400,0,0,326,7014,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,53:2:0 0,12,132:4:0 +X 1819 . C <*> 0 . DP=18;I16=9,9,0,0,580,20092,0,0,1080,64800,0,0,351,7641,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,38:2:0 0,12,124:4:0 +X 1820 . G <*> 0 . DP=18;I16=9,9,0,0,589,19883,0,0,1080,64800,0,0,351,7659,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,58:2:0 0,12,117:4:0 +X 1821 . C <*> 0 . DP=18;I16=9,9,0,0,619,22131,0,0,1080,64800,0,0,351,7693,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,60:2:0 0,12,131:4:0 +X 1822 . C <*> 0 . DP=18;I16=9,9,0,0,655,24177,0,0,1080,64800,0,0,350,7694,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,58:2:0 0,12,131:4:0 +X 1823 . C <*> 0 . DP=19;I16=10,9,0,0,703,26765,0,0,1140,68400,0,0,349,7713,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,62:2:0 0,12,138:4:0 +X 1824 . T <*> 0 . DP=19;I16=10,9,0,0,714,27628,0,0,1140,68400,0,0,349,7751,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,69:2:0 0,12,149:4:0 +X 1825 . G <*> 0 . DP=19;I16=10,9,0,0,682,24804,0,0,1140,68400,0,0,347,7709,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,61:2:0 0,12,129:4:0 +X 1826 . T <*> 0 . DP=19;I16=10,9,0,0,643,22525,0,0,1140,68400,0,0,345,7687,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,62:2:0 0,12,141:4:0 +X 1827 . G <*> 0 . DP=19;I16=10,9,0,0,722,27844,0,0,1140,68400,0,0,343,7685,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,66:2:0 0,12,134:4:0 +X 1828 . G <*> 0 . DP=18;I16=10,8,0,0,619,21719,0,0,1080,64800,0,0,342,7702,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,61:2:0 0,9,100:3:0 +X 1829 . C <*> 0 . DP=19;I16=9,9,0,0,576,19228,0,0,1080,64800,0,0,323,7413,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,59:3:0 0,9,103:3:0 +X 1830 . G <*> 0 . DP=19;I16=9,9,0,0,582,19586,0,0,1080,64800,0,0,321,7379,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,82:3:0 0,9,80:3:0 +X 1831 . T <*> 0 . DP=20;I16=10,8,0,0,605,21015,0,0,1080,64800,0,0,294,6736,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,106:4:0 0,9,101:3:0 +X 1832 . C <*> 0 . DP=19;I16=9,9,0,0,675,25747,0,0,1080,64800,0,0,319,7359,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,110:4:0 0,9,105:3:0 +X 1833 . T <*> 0 . DP=18;I16=8,8,0,0,565,20733,0,0,960,57600,0,0,295,6747,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,9,105:3:0 0,9,106:3:0 +X 1834 . C <*> 0 . DP=19;I16=9,9,0,0,654,24424,0,0,1037,61489,0,0,321,7399,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,104:4:0 0,9,107:3:0 +X 1835 . T <*> 0 . DP=18;I16=9,9,0,0,641,23505,0,0,1037,61489,0,0,347,7965,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,123:4:0 0,9,115:3:0 +X 1836 . C <*> 0 . DP=18;I16=9,9,0,0,657,24427,0,0,1037,61489,0,0,350,8016,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,127:4:0 0,9,108:3:0 +X 1837 . C <*> 0 . DP=18;I16=9,9,0,0,586,20044,0,0,1037,61489,0,0,352,8030,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,233:11:0 0,12,114:4:0 0,9,108:3:0 +X 1838 . C <*> 0 . DP=18;I16=9,9,0,0,655,24607,0,0,1037,61489,0,0,354,8056,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,120:4:0 0,9,107:3:0 +X 1839 . T <*> 0 . DP=18;I16=9,7,0,0,557,20543,0,0,917,54289,0,0,321,7369,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,30,231:10:0 0,9,103:3:0 0,9,119:3:0 +X 1840 . C <*> 0 . DP=18;I16=9,9,0,0,637,23295,0,0,1037,61489,0,0,358,8144,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,116:4:0 0,9,109:3:0 +X 1841 . C <*> 0 . DP=18;I16=9,9,0,0,622,22458,0,0,1037,61489,0,0,360,8206,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,252:11:0 0,12,121:4:0 0,9,108:3:0 +X 1842 . C <*> 0 . DP=18;I16=9,9,0,0,672,26064,0,0,1037,61489,0,0,362,8280,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,124:4:0 0,9,108:3:0 +X 1843 . T <*> 0 . DP=18;I16=9,9,0,0,630,22746,0,0,1037,61489,0,0,364,8366,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,243:11:0 0,12,131:4:0 0,9,107:3:0 +X 1844 . T <*> 0 . DP=18;I16=9,9,0,0,618,21618,0,0,1037,61489,0,0,366,8464,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,240:11:0 0,12,137:4:0 0,9,98:3:0 +X 1845 . G <*> 0 . DP=18;I16=9,9,0,0,644,23976,0,0,1037,61489,0,0,368,8574,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,138:4:0 0,9,82:3:0 +X 1846 . C <*> 0 . DP=18;I16=9,9,0,0,687,26809,0,0,1037,61489,0,0,370,8696,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,129:4:0 0,9,100:3:0 +X 1847 . T <*> 0 . DP=18;I16=9,9,0,0,675,25529,0,0,1037,61489,0,0,373,8829,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,132:4:0 0,6,76:2:0 +X 1848 . G <*> 0 . DP=18;I16=9,9,0,0,597,20845,0,0,1037,61489,0,0,377,8973,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,118:4:0 0,6,64:2:0 +X 1849 . T <*> 0 . DP=20;I16=9,10,0,0,614,20770,0,0,1097,65089,0,0,380,9078,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,119:4:0 0,6,71:2:0 +X 1850 . C <*> 0 . DP=19;I16=8,11,0,0,684,25154,0,0,1097,65089,0,0,409,9769,0,0;QS=3,0;MQSB=0.902014;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,120:4:0 0,3,37:1:0 +X 1851 . A <*> 0 . DP=20;I16=9,11,0,0,738,27838,0,0,1157,68689,0,0,413,9847,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,143:4:0 0,3,41:1:0 +X 1852 . G <*> 0 . DP=19;I16=8,11,0,0,639,22239,0,0,1097,65089,0,0,392,9264,0,0;QS=3,0;MQSB=0.902014;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,117:4:0 0,3,36:1:0 +X 1853 . G <*> 0 . DP=20;I16=9,11,0,0,627,20873,0,0,1157,68689,0,0,396,9322,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,127:5:0 0,3,38:1:0 +X 1854 . A <*> 0 . DP=22;I16=10,11,0,0,674,22428,0,0,1217,72289,0,0,401,9397,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,145:5:0 0,3,38:1:0 +X 1855 . C <*> 0 . DP=22;I16=10,12,0,0,771,27949,0,0,1277,75889,0,0,407,9441,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,132:5:0 0,3,37:1:0 +X 1856 . A <*> 0 . DP=22;I16=10,12,0,0,806,30230,0,0,1277,75889,0,0,412,9456,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,146:5:0 0,3,41:1:0 +X 1857 . G <*> 0 . DP=22;I16=10,12,0,0,699,23919,0,0,1277,75889,0,0,416,9442,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,134:5:0 0,3,35:1:0 +X 1858 . T <*> 0 . DP=23;I16=10,13,0,0,773,26797,0,0,1337,79489,0,0,419,9399,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,148:5:0 0,3,37:1:0 +X 1859 . G <*> 0 . DP=23;I16=10,13,0,0,798,28594,0,0,1337,79489,0,0,423,9379,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,146:5:0 0,3,36:1:0 +X 1860 . G <*> 0 . DP=23;I16=10,13,0,0,726,23842,0,0,1337,79489,0,0,425,9283,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,126:5:0 0,3,33:1:0 +X 1861 . T <*> 0 . DP=23;I16=10,13,0,0,741,24793,0,0,1337,79489,0,0,425,9113,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,143:5:0 0,3,39:1:0 +X 1862 . C <*> 0 . DP=23;I16=10,12,0,0,738,25732,0,0,1277,75889,0,0,403,8487,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,135:5:0 0,3,34:1:0 +X 1863 . C <*> 0 . DP=24;I16=10,13,0,0,804,29186,0,0,1337,79489,0,0,400,8232,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,133:5:0 0,3,36:1:0 +X 1864 . T <*> 0 . DP=24;I16=11,11,0,0,766,27572,0,0,1277,75889,0,0,392,8174,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,125:4:0 0,3,37:1:0 +X 1865 . G <*> 0 . DP=24;I16=11,13,0,0,860,31394,0,0,1397,83089,0,0,425,8621,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,154:5:0 0,3,38:1:0 +X 1866 . G <*> 0 . DP=24;I16=11,13,0,0,795,27503,0,0,1397,83089,0,0,425,8551,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,152:5:0 0,3,36:1:0 +X 1867 . C <*> 0 . DP=24;I16=9,13,0,0,726,24886,0,0,1320,79200,0,0,375,7263,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,122:5:0 0,3,38:1:0 +X 1868 . C <*> 0 . DP=24;I16=11,12,0,0,857,32293,0,0,1337,79489,0,0,411,8311,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,118:4:0 0,3,41:1:0 +X 1869 . A T,<*> 0 . DP=24;I16=6,9,5,4,531,19001,268,8660,857,50689,540,32400,273,5667,152,2866;QS=1.4724,1.5276,0;VDB=0.928022;SGB=-11.9537;RPB=0.984127;MQB=0.96464;MQSB=0.931547;BQB=0.359155;MQ0F=0 PL:DP:DV 115,0,224,148,245,255:18:7 16,0,104,28,107,128:5:1 42,3,0,42,3,42:1:1 +X 1870 . C <*> 0 . DP=25;I16=11,13,0,0,804,27826,0,0,1397,83089,0,0,425,8591,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,127:5:0 0,3,36:1:0 +X 1871 . C <*> 0 . DP=25;I16=11,14,0,0,761,24187,0,0,1457,86689,0,0,428,8690,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,128:6:0 0,3,29:1:0 +X 1872 . G <*> 0 . DP=25;I16=10,14,0,0,763,25437,0,0,1397,83089,0,0,425,8803,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,132:6:0 0,3,43:1:0 +X 1873 . G <*> 0 . DP=26;I16=11,15,0,0,790,25548,0,0,1517,90289,0,0,429,8931,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,151:7:0 0,3,43:1:0 +X 1874 . G <*> 0 . DP=27;I16=11,16,0,0,861,29013,0,0,1577,93889,0,0,430,9076,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,172:8:0 0,3,43:1:0 +X 1875 . G <*> 0 . DP=26;I16=11,15,0,0,800,26216,0,0,1517,90289,0,0,431,9155,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,168:7:0 0,3,42:1:0 +X 1876 . C <*> 0 . DP=26;I16=10,15,0,0,894,32714,0,0,1457,86689,0,0,432,9268,0,0;QS=3,0;MQSB=0.9171;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,171:7:0 0,3,41:1:0 +X 1877 . T <*> 0 . DP=25;I16=9,15,0,0,848,30804,0,0,1397,83089,0,0,409,8787,0,0;QS=3,0;MQSB=0.904837;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,163:6:0 0,3,42:1:0 +X 1878 . C <*> 0 . DP=25;I16=10,15,0,0,906,33478,0,0,1457,86689,0,0,434,9488,0,0;QS=3,0;MQSB=0.9171;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,166:7:0 0,3,40:1:0 +X 1879 . A <*> 0 . DP=26;I16=10,16,0,0,911,32761,0,0,1517,90289,0,0,433,9543,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,191:8:0 0,3,40:1:0 +X 1880 . C <*> 0 . DP=26;I16=10,16,0,0,790,24876,0,0,1517,90289,0,0,431,9527,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,152:8:0 0,3,31:1:0 +X 1881 . G <*> 0 . DP=27;I16=10,15,0,0,782,25352,0,0,1500,90000,0,0,380,8288,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,144:7:0 0,3,42:1:0 +X 1882 . G <*> 0 . DP=28;I16=12,15,0,0,937,33215,0,0,1577,93889,0,0,406,8952,0,0;QS=3,0;MQSB=0.935229;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,164:7:0 0,3,42:1:0 +X 1883 . A <*> 0 . DP=29;I16=14,15,0,0,998,35394,0,0,1697,101089,0,0,434,9646,0,0;QS=3,0;MQSB=0.947838;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,24,180:8:0 0,3,43:1:0 +X 1884 . G <*> 0 . DP=29;I16=14,15,0,0,1036,37926,0,0,1697,101089,0,0,437,9647,0,0;QS=3,0;MQSB=0.947838;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,24,202:8:0 0,3,42:1:0 +X 1885 . C <*> 0 . DP=28;I16=14,13,0,0,925,32305,0,0,1577,93889,0,0,430,9560,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,182:7:0 0,3,42:1:0 +X 1886 . C <*> 0 . DP=26;I16=13,13,0,0,826,27194,0,0,1517,90289,0,0,447,9745,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,166:8:0 0,3,32:1:0 +X 1887 . G <*> 0 . DP=26;I16=12,13,0,0,798,26554,0,0,1500,90000,0,0,428,9212,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,185:8:0 0,3,40:1:0 +X 1888 . C <*> 0 . DP=26;I16=13,13,0,0,901,32343,0,0,1517,90289,0,0,459,9957,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,178:8:0 0,3,39:1:0 +X 1889 . C <*> 0 . DP=25;I16=13,11,0,0,825,29127,0,0,1397,83089,0,0,444,9612,0,0;QS=3,0;MQSB=0.950498;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,187:7:0 0,3,37:1:0 +X 1890 . C <*> 0 . DP=25;I16=13,12,0,0,913,34029,0,0,1457,86689,0,0,471,10173,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,198:8:0 0,3,40:1:0 +X 1891 . T <*> 0 . DP=25;I16=13,12,0,0,912,34028,0,0,1457,86689,0,0,477,10317,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,212:8:0 0,3,39:1:0 +X 1892 . G <*> 0 . DP=25;I16=12,12,0,0,885,33149,0,0,1397,83089,0,0,458,9860,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,166:7:0 0,3,37:1:0 +X 1893 . T <*> 0 . DP=26;I16=14,12,0,0,920,33494,0,0,1517,90289,0,0,489,10677,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,205:8:0 0,6,72:2:0 +X 1894 . G <*> 0 . DP=26;I16=14,12,0,0,934,35048,0,0,1517,90289,0,0,495,10843,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,188:8:0 0,6,75:2:0 +X 1895 . C <*> 0 . DP=26;I16=13,12,0,0,882,31980,0,0,1500,90000,0,0,476,10408,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,180:8:0 0,6,73:2:0 +X 1896 . C <*> 0 . DP=26;I16=14,11,0,0,827,28179,0,0,1457,86689,0,0,482,10622,0,0;QS=3,0;MQSB=0.955682;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,154:7:0 0,6,72:2:0 +X 1897 . G <*> 0 . DP=26;I16=13,11,0,0,763,25169,0,0,1397,83089,0,0,486,10856,0,0;QS=3,0;MQSB=0.950498;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,164:7:0 0,3,27:1:0 +X 1898 . T <*> 0 . DP=27;I16=14,11,0,0,846,29526,0,0,1500,90000,0,0,492,11072,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,187:8:0 0,6,62:2:0 +X 1899 . G <*> 0 . DP=27;I16=14,11,0,0,875,32007,0,0,1500,90000,0,0,497,11213,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,188:8:0 0,6,61:2:0 +X 1900 . T <*> 0 . DP=26;I16=14,11,0,0,850,29882,0,0,1500,90000,0,0,501,11329,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,185:8:0 0,6,69:2:0 +X 1901 . A <*> 0 . DP=27;I16=15,10,0,0,842,29298,0,0,1457,86689,0,0,505,11469,0,0;QS=3,0;MQSB=0.962269;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,190:7:0 0,6,68:2:0 +X 1902 . C <*> 0 . DP=27;I16=15,12,0,0,912,31970,0,0,1577,93889,0,0,537,12267,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,184:8:0 0,6,60:2:0 +X 1903 . C <*> 0 . DP=27;I16=15,12,0,0,959,34645,0,0,1577,93889,0,0,542,12462,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,201:8:0 0,6,63:2:0 +X 1904 . T <*> 0 . DP=27;I16=16,11,0,0,1017,38757,0,0,1577,93889,0,0,548,12682,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,221:8:0 0,6,77:2:0 +X 1905 . C <*> 0 . DP=27;I16=16,11,0,0,985,36561,0,0,1577,93889,0,0,553,12827,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,211:8:0 0,6,69:2:0 +X 1906 . T <*> 0 . DP=27;I16=16,11,0,0,1018,39242,0,0,1577,93889,0,0,558,12998,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,207:8:0 0,6,75:2:0 +X 1907 . G <*> 0 . DP=27;I16=15,11,0,0,935,34679,0,0,1517,90289,0,0,535,12419,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,187:7:0 0,6,68:2:0 +X 1908 . A <*> 0 . DP=28;I16=16,12,0,0,1023,38221,0,0,1637,97489,0,0,561,13063,0,0;QS=3,0;MQSB=0.96195;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,215:8:0 0,6,67:2:0 +X 1909 . G <*> 0 . DP=27;I16=15,12,0,0,1002,38398,0,0,1577,93889,0,0,561,12953,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,206:8:0 0,6,73:2:0 +X 1910 . C <*> 0 . DP=27;I16=14,10,0,0,855,31251,0,0,1440,86400,0,0,502,11588,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,179:7:0 0,6,71:2:0 +X 1911 . C <*> 0 . DP=27;I16=15,12,0,0,967,35429,0,0,1577,93889,0,0,561,12793,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,206:8:0 0,6,71:2:0 +X 1912 . C <*> 0 . DP=27;I16=15,12,0,0,1024,39272,0,0,1577,93889,0,0,561,12743,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,217:8:0 0,6,73:2:0 +X 1913 . T <*> 0 . DP=27;I16=15,12,0,0,1028,39768,0,0,1577,93889,0,0,561,12713,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,228:8:0 0,6,77:2:0 +X 1914 . C <*> 0 . DP=27;I16=15,12,0,0,1010,38762,0,0,1577,93889,0,0,561,12703,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,221:8:0 0,6,75:2:0 +X 1915 . T C,<*> 0 . DP=27;I16=14,12,1,0,974,37184,16,256,1560,93600,17,289,543,12389,18,324;QS=2.97351,0.0264901,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.958048;BQB=1;MQ0F=0 PL:DP:DV 0,34,255,48,255,255:17:1 0,24,231,24,231,231:8:0 0,6,60,6,60,60:2:0 +X 1916 . G T,<*> 0 . DP=27;I16=14,12,1,0,991,38291,15,225,1560,93600,17,289,544,12454,17,289;QS=2.97581,0.0241935,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.958048;BQB=1;MQ0F=0 PL:DP:DV 0,35,255,48,255,255:17:1 0,24,226,24,226,226:8:0 0,6,69,6,69,69:2:0 +X 1917 . C <*> 0 . DP=27;I16=15,12,0,0,1030,39740,0,0,1577,93889,0,0,561,12793,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,214:8:0 0,6,73:2:0 +X 1918 . A <*> 0 . DP=27;I16=15,11,0,0,963,36201,0,0,1517,90289,0,0,542,12502,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,217:8:0 0,6,72:2:0 +X 1919 . C <*> 0 . DP=27;I16=15,12,0,0,987,36651,0,0,1577,93889,0,0,560,12902,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,214:8:0 0,6,72:2:0 +X 1920 . A T,<*> 0 . DP=29;I16=15,12,0,1,1007,38337,14,196,1546,91130,60,3600,538,12518,21,441;QS=2.97647,0.0235294,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.999735;BQB=1;MQ0F=0 PL:DP:DV 0,36,255,48,255,255:17:1 0,24,225,24,225,225:8:0 0,9,101,9,101,101:3:0 +X 1921 . G <*> 0 . DP=30;I16=15,14,0,0,1059,39815,0,0,1666,98330,0,0,542,12474,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,182:7:0 0,12,132:4:0 +X 1922 . T <*> 0 . DP=29;I16=14,14,0,0,1013,37513,0,0,1649,98041,0,0,532,12418,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,197:7:0 0,12,134:4:0 +X 1923 . G <*> 0 . DP=28;I16=14,14,0,0,1034,38974,0,0,1606,94730,0,0,545,12629,0,0;QS=3,0;MQSB=0.999736;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,188:7:0 0,12,126:4:0 +X 1924 . C <*> 0 . DP=27;I16=13,13,0,0,965,36587,0,0,1486,87530,0,0,521,12017,0,0;QS=3,0;MQSB=0.999671;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,183:7:0 0,12,116:4:0 +X 1925 . C <*> 0 . DP=27;I16=14,13,0,0,987,37021,0,0,1546,91130,0,0,546,12626,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,187:7:0 0,12,124:4:0 +X 1926 . T <*> 0 . DP=27;I16=14,13,0,0,1031,40057,0,0,1546,91130,0,0,545,12581,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,197:7:0 0,12,141:4:0 +X 1927 . T <*> 0 . DP=27;I16=13,13,0,0,959,35773,0,0,1529,90841,0,0,538,12522,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,191:7:0 0,12,133:4:0 +X 1928 . C <*> 0 . DP=27;I16=13,13,0,0,986,38264,0,0,1529,90841,0,0,538,12532,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,189:7:0 0,12,125:4:0 +X 1929 . T <*> 0 . DP=27;I16=13,13,0,0,990,38630,0,0,1529,90841,0,0,538,12562,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,189:7:0 0,12,139:4:0 +X 1930 . G <*> 0 . DP=26;I16=13,11,0,0,905,34865,0,0,1409,83641,0,0,521,12271,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,179:6:0 0,9,99:3:0 +X 1931 . C <*> 0 . DP=27;I16=15,12,0,0,967,36293,0,0,1546,91130,0,0,540,12578,0,0;QS=3,0;MQSB=0.99881;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,165:6:0 0,12,121:4:0 +X 1932 . T <*> 0 . DP=27;I16=14,13,0,0,998,38154,0,0,1546,91130,0,0,541,12605,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,143:5:0 0,15,146:5:0 +X 1933 . T <*> 0 . DP=27;I16=14,13,0,0,962,35344,0,0,1546,91130,0,0,542,12602,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,142:5:0 0,15,158:5:0 +X 1934 . G <*> 0 . DP=27;I16=13,13,0,0,987,38219,0,0,1529,90841,0,0,543,12569,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,134:5:0 0,15,143:5:0 +X 1935 . C <*> 0 . DP=27;I16=14,12,0,0,963,36627,0,0,1529,90841,0,0,520,11930,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,162:6:0 0,15,154:5:0 +X 1936 . C <*> 0 . DP=27;I16=14,13,0,0,1018,39406,0,0,1589,94441,0,0,547,12561,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,177:6:0 0,15,159:5:0 +X 1937 . T <*> 0 . DP=27;I16=14,13,0,0,1036,40636,0,0,1589,94441,0,0,547,12489,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,182:6:0 0,15,170:5:0 +X 1938 . G <*> 0 . DP=27;I16=14,13,0,0,1001,38377,0,0,1589,94441,0,0,546,12392,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,166:6:0 0,15,155:5:0 +X 1939 . T <*> 0 . DP=27;I16=14,12,0,0,964,36430,0,0,1560,93600,0,0,525,11909,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,167:6:0 0,12,144:4:0 +X 1940 . G <*> 0 . DP=27;I16=14,13,0,0,1003,37937,0,0,1589,94441,0,0,542,12172,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,159:6:0 0,15,155:5:0 +X 1941 . G <*> 0 . DP=27;I16=14,13,0,0,1004,38072,0,0,1589,94441,0,0,540,12098,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,176:6:0 0,15,156:5:0 +X 1942 . C <*> 0 . DP=27;I16=14,12,0,0,996,38790,0,0,1560,93600,0,0,516,11564,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,174:6:0 0,12,140:4:0 +X 1943 . T <*> 0 . DP=27;I16=14,13,0,0,1044,40952,0,0,1589,94441,0,0,536,12022,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,184:6:0 0,15,167:5:0 +X 1944 . T <*> 0 . DP=27;I16=14,13,0,0,987,37237,0,0,1589,94441,0,0,533,11971,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,175:6:0 0,15,170:5:0 +X 1945 . T <*> 0 . DP=27;I16=14,13,0,0,993,37067,0,0,1589,94441,0,0,530,11946,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,174:6:0 0,15,171:5:0 +X 1946 . G <*> 0 . DP=27;I16=14,13,0,0,1013,38617,0,0,1589,94441,0,0,526,11896,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,162:6:0 0,15,162:5:0 +X 1947 . A <*> 0 . DP=26;I16=13,13,0,0,950,35522,0,0,1529,90841,0,0,522,11818,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,167:6:0 0,15,160:5:0 +X 1948 . G C,<*> 0 . DP=27;I16=14,12,0,1,966,36912,16,256,1560,93600,29,841,493,11135,25,625;QS=2.90361,0.0963855,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.94394;BQB=1;MQ0F=0 PL:DP:DV 0,45,255,45,255,255:15:0 0,21,190,21,190,190:7:0 1,0,123,13,126,132:5:1 +X 1949 . A <*> 0 . DP=26;I16=14,11,0,0,871,31325,0,0,1469,87241,0,0,490,11048,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,174:7:0 0,15,155:5:0 +X 1950 . A <*> 0 . DP=27;I16=14,13,0,0,1007,38049,0,0,1589,94441,0,0,511,11559,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,205:7:0 0,18,176:6:0 +X 1951 . G <*> 0 . DP=27;I16=14,13,0,0,960,35536,0,0,1589,94441,0,0,509,11469,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,180:7:0 0,18,181:6:0 +X 1952 . A <*> 0 . DP=27;I16=14,12,0,0,924,33366,0,0,1529,90841,0,0,483,10779,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,184:7:0 0,18,182:6:0 +X 1953 . A <*> 0 . DP=28;I16=15,12,0,0,925,32719,0,0,1589,94441,0,0,482,10740,0,0;QS=3,0;MQSB=0.935229;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,189:7:0 0,18,168:6:0 +X 1954 . A C,<*> 0 . DP=29;I16=14,13,0,1,929,33219,18,324,1620,97200,29,841,475,10679,25,625;QS=2.90217,0.0978261,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.949591;BQB=1;MQ0F=0 PL:DP:DV 0,45,255,45,255,255:15:0 0,21,198,21,198,198:7:0 0,0,130,15,133,141:6:1 +X 1955 . C <*> 0 . DP=29;I16=14,12,0,0,961,36067,0,0,1560,93600,0,0,451,10035,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,206:7:0 0,15,165:5:0 +X 1956 . C <*> 0 . DP=29;I16=14,13,0,0,964,35402,0,0,1620,97200,0,0,475,10573,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,196:7:0 0,15,164:5:0 +X 1957 . C <*> 0 . DP=29;I16=14,13,0,0,980,36212,0,0,1620,97200,0,0,472,10420,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,183:7:0 0,15,167:5:0 +X 1958 . C <*> 0 . DP=29;I16=15,13,0,0,1003,37293,0,0,1649,98041,0,0,493,10825,0,0;QS=3,0;MQSB=0.942064;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,191:7:0 0,18,190:6:0 +X 1959 . T <*> 0 . DP=29;I16=16,13,0,0,1112,43258,0,0,1709,101641,0,0,491,10593,0,0;QS=3,0;MQSB=0.940317;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,213:7:0 0,18,193:6:0 +X 1960 . T <*> 0 . DP=30;I16=17,13,0,0,1053,37939,0,0,1769,105241,0,0,485,10339,0,0;QS=3,0;MQSB=0.938685;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,196:7:0 0,18,186:6:0 +X 1961 . C <*> 0 . DP=30;I16=17,13,0,0,1101,41737,0,0,1769,105241,0,0,480,10122,0,0;QS=3,0;MQSB=0.938685;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,195:7:0 0,18,183:6:0 +X 1962 . T <*> 0 . DP=29;I16=17,12,0,0,1134,44582,0,0,1709,101641,0,0,477,9941,0,0;QS=3,0;MQSB=0.931617;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,208:7:0 0,18,198:6:0 +X 1963 . G <*> 0 . DP=28;I16=16,12,0,0,1066,41050,0,0,1649,98041,0,0,476,9794,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,192:7:0 0,18,188:6:0 +X 1964 . G <*> 0 . DP=28;I16=16,12,0,0,970,34764,0,0,1649,98041,0,0,475,9681,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,178:7:0 0,18,169:6:0 +X 1965 . T <*> 0 . DP=29;I16=16,12,0,0,964,34772,0,0,1649,98041,0,0,449,8977,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,196:7:0 0,18,171:6:0 +X 1966 . T <*> 0 . DP=29;I16=16,13,0,0,1029,37027,0,0,1709,101641,0,0,474,9558,0,0;QS=3,0;MQSB=0.940317;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,191:7:0 0,18,181:6:0 +X 1967 . A <*> 0 . DP=29;I16=16,13,0,0,1030,37234,0,0,1709,101641,0,0,474,9550,0,0;QS=3,0;MQSB=0.940317;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,187:7:0 0,18,182:6:0 +X 1968 . T <*> 0 . DP=29;I16=16,13,0,0,1075,40173,0,0,1709,101641,0,0,474,9578,0,0;QS=3,0;MQSB=0.940317;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,195:7:0 0,18,190:6:0 +X 1969 . A <*> 0 . DP=28;I16=16,12,0,0,992,35828,0,0,1649,98041,0,0,474,9592,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,175:6:0 0,18,186:6:0 +X 1970 . C <*> 0 . DP=28;I16=16,12,0,0,1015,37503,0,0,1649,98041,0,0,474,9642,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,170:6:0 0,18,180:6:0 +X 1971 . A <*> 0 . DP=29;I16=16,13,0,0,1073,40273,0,0,1709,101641,0,0,474,9728,0,0;QS=3,0;MQSB=0.940317;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,178:6:0 0,21,206:7:0 +X 1972 . T <*> 0 . DP=30;I16=16,14,0,0,1068,38978,0,0,1769,105241,0,0,475,9851,0,0;QS=3,0;MQSB=0.946202;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,176:6:0 0,21,203:7:0 +X 1973 . A <*> 0 . DP=30;I16=16,13,0,0,1046,38070,0,0,1740,104400,0,0,452,9388,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,172:6:0 0,18,196:6:0 +X 1974 . A <*> 0 . DP=29;I16=16,13,0,0,1086,41474,0,0,1709,101641,0,0,477,10065,0,0;QS=3,0;MQSB=0.940317;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,157:5:0 0,21,214:7:0 +X 1975 . G <*> 0 . DP=28;I16=16,12,0,0,1067,41171,0,0,1649,98041,0,0,478,10156,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,133:4:0 0,21,195:7:0 +X 1976 . A <*> 0 . DP=28;I16=16,12,0,0,981,34839,0,0,1649,98041,0,0,478,10234,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,125:4:0 0,21,199:7:0 +X 1977 . C <*> 0 . DP=28;I16=16,12,0,0,1009,37471,0,0,1649,98041,0,0,477,10297,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,132:4:0 0,21,194:7:0 +X 1978 . A <*> 0 . DP=28;I16=16,12,0,0,1082,42132,0,0,1649,98041,0,0,476,10394,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,144:4:0 0,21,220:7:0 +X 1979 . G <*> 0 . DP=28;I16=16,11,0,0,1019,38927,0,0,1589,94441,0,0,454,10064,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,122:4:0 0,21,208:7:0 +X 1980 . C <*> 0 . DP=27;I16=16,10,0,0,932,34456,0,0,1529,90841,0,0,452,10114,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,107:3:0 0,21,197:7:0 +X 1981 . C <*> 0 . DP=28;I16=16,12,0,0,998,36510,0,0,1649,98041,0,0,469,10479,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,101:3:0 0,24,219:8:0 +X 1982 . A <*> 0 . DP=29;I16=16,12,0,0,1035,38815,0,0,1649,98041,0,0,472,10548,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,110:3:0 0,27,254:9:0 +X 1983 . G <*> 0 . DP=28;I16=16,12,0,0,1048,40322,0,0,1649,98041,0,0,477,10599,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,96:3:0 0,27,249:9:0 +X 1984 . A <*> 0 . DP=27;I16=16,11,0,0,1024,39232,0,0,1589,94441,0,0,482,10632,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,70:2:0 0,27,255:9:0 +X 1985 . G <*> 0 . DP=27;I16=16,11,0,0,1009,38449,0,0,1589,94441,0,0,487,10695,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,66:2:0 0,27,231:9:0 +X 1986 . A <*> 0 . DP=27;I16=16,10,0,0,926,33696,0,0,1560,93600,0,0,466,10112,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,76:2:0 0,24,223:8:0 +X 1987 . A <*> 0 . DP=28;I16=17,11,0,0,1034,39088,0,0,1649,98041,0,0,495,10807,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,78:2:0 0,27,247:9:0 +X 1988 . G <*> 0 . DP=28;I16=17,11,0,0,1050,39980,0,0,1649,98041,0,0,499,10855,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,63:2:0 0,27,239:9:0 +X 1989 . G <*> 0 . DP=28;I16=17,10,0,0,994,37610,0,0,1589,94441,0,0,493,10801,0,0;QS=3,0;MQSB=0.912952;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,73:2:0 0,27,237:9:0 +X 1990 . G T,<*> 0 . DP=28;I16=17,9,0,1,965,36359,33,1089,1560,93600,29,841,472,10250,25,625;QS=2.90675,0.0932476,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.912952;BQB=1;MQ0F=0 PL:DP:DV 0,48,255,48,255,255:16:0 0,6,71,6,71,71:2:0 2,0,195,26,198,215:9:1 +X 1991 . A <*> 0 . DP=28;I16=17,11,0,0,1017,38203,0,0,1649,98041,0,0,507,10975,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,60:2:0 0,27,250:9:0 +X 1992 . G <*> 0 . DP=28;I16=17,11,0,0,1028,38852,0,0,1649,98041,0,0,509,11039,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,62:2:0 0,27,231:9:0 +X 1993 . T <*> 0 . DP=28;I16=17,11,0,0,1015,37325,0,0,1649,98041,0,0,511,11131,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,59:2:0 0,27,243:9:0 +X 1994 . T <*> 0 . DP=27;I16=16,11,0,0,942,33698,0,0,1589,94441,0,0,514,11250,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,54:2:0 0,24,216:8:0 +X 1995 . G <*> 0 . DP=28;I16=16,11,0,0,960,35432,0,0,1620,97200,0,0,492,10770,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,66:2:0 0,21,188:7:0 +X 1996 . C <*> 0 . DP=29;I16=17,12,0,0,1022,37426,0,0,1709,101641,0,0,519,11469,0,0;QS=3,0;MQSB=0.931617;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,64:2:0 0,24,192:8:0 +X 1997 . C <*> 0 . DP=29;I16=17,11,0,0,934,32858,0,0,1649,98041,0,0,520,11524,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,70:2:0 0,24,193:8:0 +X 1998 . C <*> 0 . DP=29;I16=17,12,0,0,1027,37843,0,0,1709,101641,0,0,522,11562,0,0;QS=3,0;MQSB=0.931617;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,69:2:0 0,24,222:8:0 +X 1999 . A <*> 0 . DP=28;I16=17,11,0,0,1073,41493,0,0,1649,98041,0,0,525,11627,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,72:2:0 0,21,206:7:0 +X 2000 . G <*> 0 . DP=28;I16=16,11,0,0,1036,40576,0,0,1589,94441,0,0,511,11395,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,72:2:0 0,18,168:6:0 +X 2001 . G <*> 0 . DP=28;I16=15,11,0,0,955,35661,0,0,1529,90841,0,0,489,10853,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,62:2:0 0,18,172:6:0 +X 2002 . G <*> 0 . DP=28;I16=17,10,0,0,907,32227,0,0,1620,97200,0,0,519,11663,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,53:2:0 0,18,163:6:0 +X 2003 . T <*> 0 . DP=28;I16=17,11,0,0,920,31866,0,0,1649,98041,0,0,541,12163,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,49:2:0 0,21,190:7:0 +X 2004 . G <*> 0 . DP=27;I16=16,10,0,0,970,36928,0,0,1560,93600,0,0,530,12110,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,57:2:0 0,18,178:6:0 +X 2005 . G <*> 0 . DP=27;I16=16,10,0,0,868,30936,0,0,1560,93600,0,0,536,12370,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,59:2:0 0,18,153:6:0 +X 2006 . C <*> 0 . DP=27;I16=16,10,0,0,968,37046,0,0,1560,93600,0,0,541,12605,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,73:2:0 0,18,166:6:0 +X 2007 . A <*> 0 . DP=27;I16=16,11,0,0,1000,37396,0,0,1589,94441,0,0,556,12882,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,76:2:0 0,21,193:7:0 +X 2008 . C <*> 0 . DP=26;I16=16,10,0,0,964,36892,0,0,1529,90841,0,0,555,12833,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,73:2:0 0,21,183:7:0 +X 2009 . A <*> 0 . DP=26;I16=16,10,0,0,997,38955,0,0,1529,90841,0,0,554,12802,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,74:2:0 0,21,210:7:0 +X 2010 . G <*> 0 . DP=26;I16=16,9,0,0,936,36208,0,0,1500,90000,0,0,542,12640,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,73:2:0 0,18,169:6:0 +X 2011 . C <*> 0 . DP=26;I16=16,9,0,0,966,37960,0,0,1500,90000,0,0,541,12617,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,74:2:0 0,18,175:6:0 +X 2012 . A <*> 0 . DP=27;I16=16,11,0,0,956,35018,0,0,1589,94441,0,0,548,12676,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,74:2:0 0,21,189:7:0 +X 2013 . C <*> 0 . DP=27;I16=15,10,0,0,876,31370,0,0,1500,90000,0,0,514,11950,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,69:2:0 0,18,160:6:0 +X 2014 . G <*> 0 . DP=27;I16=17,10,0,0,903,31239,0,0,1589,94441,0,0,545,12591,0,0;QS=3,0;MQSB=0.912952;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,80:3:0 0,18,160:6:0 +X 2015 . T <*> 0 . DP=27;I16=17,10,0,0,999,37507,0,0,1589,94441,0,0,545,12577,0,0;QS=3,0;MQSB=0.912952;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,95:3:0 0,18,178:6:0 +X 2016 . T <*> 0 . DP=27;I16=17,10,0,0,971,35649,0,0,1589,94441,0,0,545,12583,0,0;QS=3,0;MQSB=0.912952;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,93:3:0 0,18,178:6:0 +X 2017 . G <*> 0 . DP=28;I16=17,11,0,0,1013,37849,0,0,1649,98041,0,0,545,12609,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,9,91:3:0 0,18,172:6:0 +X 2018 . C <*> 0 . DP=28;I16=17,11,0,0,1060,41414,0,0,1649,98041,0,0,546,12656,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,9,97:3:0 0,18,169:6:0 +X 2019 . T <*> 0 . DP=28;I16=17,11,0,0,1083,42253,0,0,1649,98041,0,0,547,12725,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,9,106:3:0 0,18,187:6:0 +X 2020 . G <*> 0 . DP=29;I16=18,11,0,0,1095,42063,0,0,1678,98882,0,0,548,12816,0,0;QS=3,0;MQSB=0.987702;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,9,85:3:0 0,18,175:6:0 +X 2021 . C <*> 0 . DP=29;I16=18,11,0,0,1081,41535,0,0,1709,101641,0,0,551,12877,0,0;QS=3,0;MQSB=0.969907;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,97:3:0 0,15,167:5:0 +X 2022 . C <*> 0 . DP=30;I16=19,11,0,0,1115,42003,0,0,1769,105241,0,0,555,12907,0,0;QS=3,0;MQSB=0.972375;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,92:3:0 0,18,177:6:0 +X 2023 . A <*> 0 . DP=30;I16=19,10,0,0,1063,39991,0,0,1709,101641,0,0,549,12837,0,0;QS=3,0;MQSB=0.974027;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,9,96:3:0 0,18,186:6:0 +X 2024 . G <*> 0 . DP=32;I16=20,12,0,0,1168,43872,0,0,1889,112441,0,0,564,12982,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,92:3:0 0,24,203:8:0 +X 2025 . T <*> 0 . DP=32;I16=20,12,0,0,1150,42122,0,0,1889,112441,0,0,569,12981,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,87:3:0 0,24,226:8:0 +X 2026 . T <*> 0 . DP=32;I16=20,12,0,0,1130,40724,0,0,1889,112441,0,0,572,12908,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,94:3:0 0,24,208:8:0 +X 2027 . A <*> 0 . DP=32;I16=19,12,0,0,1121,40871,0,0,1829,108841,0,0,550,12240,0,0;QS=3,0;MQSB=0.970829;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,84:3:0 0,21,207:7:0 +X 2028 . C <*> 0 . DP=32;I16=20,12,0,0,1242,48548,0,0,1889,112441,0,0,577,12803,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,94:3:0 0,24,228:8:0 +X 2029 . T <*> 0 . DP=32;I16=20,12,0,0,1229,47605,0,0,1889,112441,0,0,578,12724,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,102:3:0 0,24,236:8:0 +X 2030 . G <*> 0 . DP=32;I16=20,12,0,0,1222,47140,0,0,1889,112441,0,0,579,12679,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,93:3:0 0,24,216:8:0 +X 2031 . C <*> 0 . DP=31;I16=19,12,0,0,1150,43656,0,0,1829,108841,0,0,581,12667,0,0;QS=3,0;MQSB=0.970829;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,9,96:3:0 0,24,204:8:0 +X 2032 . C <*> 0 . DP=31;I16=19,12,0,0,1157,44035,0,0,1829,108841,0,0,583,12687,0,0;QS=3,0;MQSB=0.970829;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,9,90:3:0 0,24,210:8:0 +X 2033 . A <*> 0 . DP=30;I16=19,11,0,0,1091,40223,0,0,1769,105241,0,0,585,12689,0,0;QS=3,0;MQSB=0.972375;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,9,93:3:0 0,21,203:7:0 +X 2034 . T <*> 0 . DP=30;I16=19,11,0,0,1104,41498,0,0,1769,105241,0,0,587,12723,0,0;QS=3,0;MQSB=0.972375;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,9,91:3:0 0,21,208:7:0 +X 2035 . T <*> 0 . DP=29;I16=18,11,0,0,1084,41024,0,0,1709,101641,0,0,589,12739,0,0;QS=3,0;MQSB=0.969907;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,69:2:0 0,21,211:7:0 +X 2036 . T <*> 0 . DP=29;I16=18,11,0,0,1080,40612,0,0,1709,101641,0,0,591,12787,0,0;QS=3,0;MQSB=0.969907;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,67:2:0 0,21,216:7:0 +X 2037 . T <*> 0 . DP=29;I16=18,11,0,0,1082,40956,0,0,1709,101641,0,0,592,12818,0,0;QS=3,0;MQSB=0.969907;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,69:2:0 0,21,217:7:0 +X 2038 . C <*> 0 . DP=29;I16=18,11,0,0,1117,43573,0,0,1709,101641,0,0,592,12832,0,0;QS=3,0;MQSB=0.969907;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,69:2:0 0,21,211:7:0 +X 2039 . A <*> 0 . DP=29;I16=18,11,0,0,1067,39581,0,0,1709,101641,0,0,592,12878,0,0;QS=3,0;MQSB=0.969907;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,72:2:0 0,21,212:7:0 +X 2040 . C <*> 0 . DP=29;I16=18,11,0,0,1077,40469,0,0,1709,101641,0,0,590,12856,0,0;QS=3,0;MQSB=0.969907;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,69:2:0 0,21,196:7:0 +X 2041 . G A,<*> 0 . DP=31;I16=6,5,12,7,389,14023,721,28149,660,39600,1109,65641,235,5607,353,7259;QS=0.917304,2.0827,0;VDB=0.816435;SGB=-4.18892;RPB=0.88473;MQB=0.972375;MQSB=0.968257;BQB=0.311275;MQ0F=0 PL:DP:DV 229,0,212,255,245,255:21:11 32,0,24,35,27,59:2:1 223,21,0,223,21,223:7:7 +X 2042 . G <*> 0 . DP=32;I16=18,14,0,0,1189,45617,0,0,1889,112441,0,0,588,12910,0,0;QS=3,0;MQSB=0.965264;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,9,86:3:0 0,21,206:7:0 +X 2043 . G <*> 0 . DP=32;I16=17,14,0,0,1115,41585,0,0,1829,108841,0,0,581,12891,0,0;QS=3,0;MQSB=0.962133;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,90:3:0 0,21,197:7:0 +X 2044 . C <*> 0 . DP=32;I16=18,14,0,0,1213,47029,0,0,1889,112441,0,0,588,13006,0,0;QS=3,0;MQSB=0.965264;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,9,85:3:0 0,21,207:7:0 +X 2045 . A <*> 0 . DP=32;I16=18,14,0,0,1181,44527,0,0,1889,112441,0,0,588,13108,0,0;QS=3,0;MQSB=0.965264;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,9,83:3:0 0,21,213:7:0 +X 2046 . T <*> 0 . DP=32;I16=18,14,0,0,1197,45135,0,0,1889,112441,0,0,587,13195,0,0;QS=3,0;MQSB=0.965264;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,9,103:3:0 0,21,216:7:0 +X 2047 . G <*> 0 . DP=34;I16=17,16,0,0,1248,47798,0,0,1949,116041,0,0,557,12491,0,0;QS=3,0;MQSB=0.959328;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,9,88:3:0 0,18,195:6:0 +X 2048 . A <*> 0 . DP=34;I16=18,16,0,0,1230,45184,0,0,2009,119641,0,0,578,13022,0,0;QS=3,0;MQSB=0.962621;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,9,87:3:0 0,21,206:7:0 +X 2049 . A <*> 0 . DP=33;I16=17,16,0,0,1207,44567,0,0,1949,116041,0,0,575,12963,0,0;QS=3,0;MQSB=0.959328;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,6,74:2:0 0,21,208:7:0 +X 2050 . A <*> 0 . DP=33;I16=16,16,0,0,1169,43313,0,0,1889,112441,0,0,545,12211,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,6,77:2:0 0,18,188:6:0 +X 2051 . T <*> 0 . DP=31;I16=16,15,0,0,1134,42164,0,0,1829,108841,0,0,567,12737,0,0;QS=3,0;MQSB=0.957006;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,6,69:2:0 0,18,170:6:0 +X 2052 . G <*> 0 . DP=31;I16=16,15,0,0,1180,45546,0,0,1829,108841,0,0,564,12664,0,0;QS=3,0;MQSB=0.957006;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,6,74:2:0 0,18,175:6:0 +X 2053 . G T,<*> 0 . DP=31;I16=15,15,0,1,1126,42672,23,529,1769,105241,60,3600,537,11991,25,625;QS=2.97307,0.0269321,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.951229;BQB=1;MQ0F=0 PL:DP:DV 0,46,255,66,255,255:23:1 0,6,71,6,71,71:2:0 0,18,180,18,180,180:6:0 +X 2054 . A <*> 0 . DP=30;I16=15,15,0,0,1123,43027,0,0,1769,105241,0,0,562,12592,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,6,78:2:0 0,18,171:6:0 +X 2055 . G <*> 0 . DP=30;I16=15,15,0,0,1156,45206,0,0,1769,105241,0,0,562,12592,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,6,66:2:0 0,18,168:6:0 +X 2056 . A <*> 0 . DP=30;I16=15,15,0,0,1124,42416,0,0,1769,105241,0,0,560,12518,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,6,71:2:0 0,18,179:6:0 +X 2057 . T <*> 0 . DP=30;I16=15,15,0,0,1094,40082,0,0,1769,105241,0,0,556,12374,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,6,72:2:0 0,18,178:6:0 +X 2058 . A <*> 0 . DP=29;I16=14,15,0,0,1035,37517,0,0,1709,101641,0,0,552,12212,0,0;QS=3,0;MQSB=0.947838;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,6,57:2:0 0,18,179:6:0 +X 2059 . A <*> 0 . DP=29;I16=14,15,0,0,1063,39615,0,0,1709,101641,0,0,548,12082,0,0;QS=3,0;MQSB=0.947838;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,6,66:2:0 0,18,188:6:0 +X 2060 . C <*> 0 . DP=28;I16=12,15,0,0,1015,39057,0,0,1589,94441,0,0,523,11499,0,0;QS=3,0;MQSB=0.935229;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,62:2:0 0,15,143:5:0 +X 2061 . A <*> 0 . DP=27;I16=12,14,0,0,950,35084,0,0,1529,90841,0,0,501,11073,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,3,41:1:0 0,15,163:5:0 +X 2062 . A <*> 0 . DP=26;I16=11,15,0,0,973,37349,0,0,1529,90841,0,0,519,11425,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,57:2:0 0,15,164:5:0 +X 2063 . C <*> 0 . DP=26;I16=11,15,0,0,1017,40149,0,0,1529,90841,0,0,517,11405,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,74:2:0 0,15,158:5:0 +X 2064 . A <*> 0 . DP=26;I16=11,15,0,0,1002,38980,0,0,1529,90841,0,0,515,11413,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,75:2:0 0,15,164:5:0 +X 2065 . G <*> 0 . DP=26;I16=12,14,0,0,1030,41232,0,0,1529,90841,0,0,514,11448,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,78:2:0 0,18,167:6:0 +X 2066 . G <*> 0 . DP=26;I16=12,14,0,0,973,37055,0,0,1529,90841,0,0,514,11510,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,75:2:0 0,18,152:6:0 +X 2067 . A <*> 0 . DP=26;I16=12,14,0,0,1005,39095,0,0,1529,90841,0,0,512,11498,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,69:2:0 0,18,187:6:0 +X 2068 . G <*> 0 . DP=26;I16=12,14,0,0,993,39005,0,0,1529,90841,0,0,509,11459,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,53:2:0 0,18,167:6:0 +X 2069 . C <*> 0 . DP=26;I16=12,14,0,0,873,29879,0,0,1529,90841,0,0,506,11442,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,59:2:0 0,18,156:6:0 +X 2070 . G <*> 0 . DP=27;I16=13,14,0,0,932,33090,0,0,1589,94441,0,0,502,11398,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,62:2:0 0,18,145:6:0 +X 2071 . A <*> 0 . DP=27;I16=13,14,0,0,946,33884,0,0,1589,94441,0,0,498,11330,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,53:2:0 0,18,177:6:0 +X 2072 . C <*> 0 . DP=25;I16=13,12,0,0,897,32897,0,0,1469,87241,0,0,496,11288,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,59:2:0 0,15,128:5:0 +X 2073 . C <*> 0 . DP=26;I16=14,12,0,0,874,30184,0,0,1529,90841,0,0,492,11168,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,53:2:0 0,15,133:5:0 +X 2074 . G <*> 0 . DP=26;I16=13,12,0,0,835,29219,0,0,1469,87241,0,0,463,10395,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,67:2:0 0,12,83:4:0 +X 2075 . C <*> 0 . DP=27;I16=15,12,0,0,989,37027,0,0,1589,94441,0,0,484,10896,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,69:2:0 0,15,115:5:0 +X 2076 . A <*> 0 . DP=27;I16=14,12,0,0,929,33551,0,0,1529,90841,0,0,470,10676,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,76:2:0 0,12,114:4:0 +X 2077 . C <*> 0 . DP=27;I16=15,12,0,0,990,37252,0,0,1589,94441,0,0,478,10724,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,65:2:0 0,15,125:5:0 +X 2078 . A <*> 0 . DP=27;I16=15,12,0,0,1023,39089,0,0,1589,94441,0,0,475,10677,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,72:2:0 0,15,148:5:0 +X 2079 . G <*> 0 . DP=28;I16=15,13,0,0,1042,39694,0,0,1649,98041,0,0,471,10605,0,0;QS=3,0;MQSB=0.956162;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,6,72:2:0 0,15,133:5:0 +X 2080 . G <*> 0 . DP=28;I16=14,13,0,0,968,35328,0,0,1589,94441,0,0,453,10333,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,6,67:2:0 0,12,108:4:0 +X 2081 . C <*> 0 . DP=26;I16=14,12,0,0,937,35303,0,0,1529,90841,0,0,467,10535,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,63:2:0 0,15,110:5:0 +X 2082 . T <*> 0 . DP=24;I16=12,12,0,0,901,34287,0,0,1409,83641,0,0,468,10532,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,71:2:0 0,12,112:4:0 +X 2083 . G <*> 0 . DP=24;I16=12,12,0,0,887,33597,0,0,1409,83641,0,0,469,10547,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,68:2:0 0,12,113:4:0 +X 2084 . C <*> 0 . DP=25;I16=13,12,0,0,938,35868,0,0,1469,87241,0,0,470,10580,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,61:2:0 0,12,115:4:0 +X 2085 . T <*> 0 . DP=25;I16=13,12,0,0,932,35282,0,0,1469,87241,0,0,472,10632,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,64:2:0 0,12,130:4:0 +X 2086 . G <*> 0 . DP=25;I16=13,12,0,0,932,35400,0,0,1469,87241,0,0,474,10704,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,61:2:0 0,12,129:4:0 +X 2087 . A <*> 0 . DP=24;I16=12,12,0,0,903,34391,0,0,1409,83641,0,0,476,10746,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,66:2:0 0,12,126:4:0 +X 2088 . G <*> 0 . DP=24;I16=12,12,0,0,880,33116,0,0,1409,83641,0,0,478,10808,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,70:2:0 0,12,121:4:0 +X 2089 . C <*> 0 . DP=25;I16=13,12,0,0,817,27419,0,0,1469,87241,0,0,480,10890,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,64:2:0 0,15,138:5:0 +X 2090 . G <*> 0 . DP=25;I16=12,12,0,0,802,27940,0,0,1409,83641,0,0,457,10319,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,63:2:0 0,12,99:4:0 +X 2091 . C <*> 0 . DP=25;I16=12,12,0,0,800,27346,0,0,1440,86400,0,0,458,10346,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,61:2:0 0,15,125:5:0 +X 2092 . G <*> 0 . DP=26;I16=13,12,0,0,838,29188,0,0,1469,87241,0,0,461,10487,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,64:2:0 0,18,133:6:0 +X 2093 . T G,<*> 0 . DP=26;I16=13,12,1,0,905,33415,17,289,1500,90000,29,841,459,10371,25,625;QS=2.97424,0.0257576,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.953497;BQB=1;MQ0F=0 PL:DP:DV 0,36,255,51,255,255:18:1 0,6,67,6,67,67:2:0 0,18,153,18,153,153:6:0 +X 2094 . C <*> 0 . DP=26;I16=14,12,0,0,949,35501,0,0,1529,90841,0,0,485,11047,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,69:2:0 0,18,142:6:0 +X 2095 . A <*> 0 . DP=25;I16=14,11,0,0,879,31219,0,0,1469,87241,0,0,487,11123,0,0;QS=3,0;MQSB=0.955682;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,72:2:0 0,18,154:6:0 +X 2096 . C <*> 0 . DP=24;I16=13,11,0,0,878,32734,0,0,1409,83641,0,0,487,11073,0,0;QS=3,0;MQSB=0.950498;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,65:2:0 0,18,161:6:0 +X 2097 . A <*> 0 . DP=24;I16=13,11,0,0,849,30671,0,0,1409,83641,0,0,487,11047,0,0;QS=3,0;MQSB=0.950498;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,56:2:0 0,18,172:6:0 +X 2098 . C <*> 0 . DP=24;I16=13,11,0,0,781,26113,0,0,1409,83641,0,0,486,10996,0,0;QS=3,0;MQSB=0.950498;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,58:2:0 0,18,139:6:0 +X 2099 . G <*> 0 . DP=23;I16=12,10,0,0,719,25109,0,0,1289,76441,0,0,460,10294,0,0;QS=3,0;MQSB=0.947103;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,3,24:1:0 0,18,129:6:0 +X 2100 . C <*> 0 . DP=25;I16=13,11,0,0,873,32759,0,0,1409,83641,0,0,457,10141,0,0;QS=3,0;MQSB=0.950498;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,87:3:0 0,18,160:6:0 +X 2101 . A <*> 0 . DP=25;I16=12,12,0,0,907,34671,0,0,1440,86400,0,0,455,9965,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,135:4:0 0,18,161:6:0 +X 2102 . G <*> 0 . DP=25;I16=13,12,0,0,930,35596,0,0,1469,87241,0,0,478,10442,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,118:4:0 0,18,151:6:0 +X 2103 . C <*> 0 . DP=25;I16=11,12,0,0,842,31630,0,0,1380,82800,0,0,432,9336,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,106:4:0 0,15,146:5:0 +X 2104 . C <*> 0 . DP=24;I16=12,12,0,0,869,32463,0,0,1409,83641,0,0,454,9810,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,126:4:0 0,15,147:5:0 +X 2105 . A <*> 0 . DP=25;I16=11,12,0,0,836,30696,0,0,1380,82800,0,0,429,9201,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,138:4:0 0,15,130:5:0 +X 2106 . T <*> 0 . DP=25;I16=12,13,0,0,897,33087,0,0,1469,87241,0,0,473,10211,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,129:4:0 0,15,146:5:0 +X 2107 . C <*> 0 . DP=25;I16=11,12,0,0,783,27185,0,0,1380,82800,0,0,425,9113,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,100:3:0 0,15,133:5:0 +X 2108 . G <*> 0 . DP=25;I16=11,13,0,0,829,29703,0,0,1440,86400,0,0,448,9730,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,122:4:0 0,15,111:5:0 +X 2109 . C <*> 0 . DP=25;I16=11,13,0,0,781,26717,0,0,1440,86400,0,0,446,9746,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,109:4:0 0,15,125:5:0 +X 2110 . G <*> 0 . DP=25;I16=12,12,0,0,804,28134,0,0,1440,86400,0,0,418,9110,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,92:3:0 0,15,117:5:0 +X 2111 . C <*> 0 . DP=25;I16=12,13,0,0,925,35081,0,0,1500,90000,0,0,441,9747,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,134:4:0 0,15,140:5:0 +X 2112 . A <*> 0 . DP=24;I16=12,12,0,0,885,33445,0,0,1440,86400,0,0,440,9782,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,129:4:0 0,15,140:5:0 +X 2113 . G <*> 0 . DP=24;I16=12,12,0,0,871,32641,0,0,1440,86400,0,0,439,9839,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,128:4:0 0,15,134:5:0 +X 2114 . C <*> 0 . DP=24;I16=12,11,0,0,844,32052,0,0,1380,82800,0,0,413,9293,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,103:3:0 0,15,126:5:0 +X 2115 . T <*> 0 . DP=23;I16=11,11,0,0,821,30869,0,0,1320,79200,0,0,412,9342,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,78:2:0 0,15,143:5:0 +X 2116 . C <*> 0 . DP=23;I16=11,12,0,0,890,34892,0,0,1380,82800,0,0,435,9985,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,102:3:0 0,15,152:5:0 +X 2117 . A <*> 0 . DP=23;I16=11,11,0,0,833,32121,0,0,1320,79200,0,0,432,9924,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,118:3:0 0,15,156:5:0 +X 2118 . G <*> 0 . DP=23;I16=12,11,0,0,842,31502,0,0,1380,82800,0,0,429,9835,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,125:4:0 0,15,147:5:0 +X 2119 . G <*> 0 . DP=23;I16=12,11,0,0,823,30553,0,0,1380,82800,0,0,426,9768,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,135:4:0 0,15,137:5:0 +X 2120 . G <*> 0 . DP=24;I16=13,11,0,0,864,32028,0,0,1440,86400,0,0,423,9723,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,137:4:0 0,15,140:5:0 +X 2121 . A <*> 0 . DP=22;I16=11,10,0,0,734,26712,0,0,1260,75600,0,0,398,9074,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,135:4:0 0,12,122:4:0 +X 2122 . T <*> 0 . DP=22;I16=11,10,0,0,752,27278,0,0,1260,75600,0,0,396,8972,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,136:4:0 0,12,123:4:0 +X 2123 . A <*> 0 . DP=22;I16=12,10,0,0,758,27024,0,0,1320,79200,0,0,419,9519,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,120:4:0 0,15,137:5:0 +X 2124 . T <*> 0 . DP=22;I16=12,10,0,0,789,28741,0,0,1320,79200,0,0,417,9465,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,128:4:0 0,15,136:5:0 +X 2125 . T <*> 0 . DP=20;I16=11,8,0,0,696,25704,0,0,1140,68400,0,0,401,9177,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,106:3:0 0,9,93:3:0 +X 2126 . A <*> 0 . DP=20;I16=11,9,0,0,717,25979,0,0,1200,72000,0,0,415,9319,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,133:4:0 0,9,95:3:0 +X 2127 . C <*> 0 . DP=21;I16=11,10,0,0,706,24426,0,0,1260,75600,0,0,413,9221,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,107:4:0 0,9,95:3:0 +X 2128 . G <*> 0 . DP=21;I16=11,10,0,0,677,22633,0,0,1260,75600,0,0,411,9091,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,116:4:0 0,9,72:3:0 +X 2129 . T <*> 0 . DP=21;I16=11,10,0,0,782,29386,0,0,1260,75600,0,0,409,8981,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,140:4:0 0,9,83:3:0 +X 2130 . G <*> 0 . DP=21;I16=11,10,0,0,766,28562,0,0,1260,75600,0,0,407,8891,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,135:4:0 0,9,87:3:0 +X 2131 . T <*> 0 . DP=21;I16=11,10,0,0,732,26216,0,0,1260,75600,0,0,405,8821,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,136:4:0 0,9,79:3:0 +X 2132 . A <*> 0 . DP=21;I16=11,10,0,0,743,26733,0,0,1260,75600,0,0,403,8771,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,135:4:0 0,9,88:3:0 +X 2133 . A <*> 0 . DP=21;I16=11,10,0,0,787,29651,0,0,1260,75600,0,0,401,8741,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,141:4:0 0,9,96:3:0 +X 2134 . C <*> 0 . DP=21;I16=11,10,0,0,804,31100,0,0,1260,75600,0,0,399,8731,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,138:4:0 0,9,86:3:0 +X 2135 . T <*> 0 . DP=22;I16=11,11,0,0,831,32197,0,0,1320,79200,0,0,397,8741,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,153:4:0 0,12,119:4:0 +X 2136 . C <*> 0 . DP=22;I16=11,11,0,0,760,26892,0,0,1320,79200,0,0,395,8721,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,124:4:0 0,12,127:4:0 +X 2137 . G <*> 0 . DP=22;I16=11,11,0,0,745,26047,0,0,1320,79200,0,0,393,8721,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,121:4:0 0,12,102:4:0 +X 2138 . A <*> 0 . DP=22;I16=11,11,0,0,816,30934,0,0,1320,79200,0,0,391,8741,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,128:4:0 0,12,139:4:0 +X 2139 . C <*> 0 . DP=22;I16=11,11,0,0,839,32237,0,0,1320,79200,0,0,389,8781,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,138:4:0 0,12,125:4:0 +X 2140 . A <*> 0 . DP=22;I16=11,11,0,0,826,31300,0,0,1320,79200,0,0,387,8841,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,140:4:0 0,12,138:4:0 +X 2141 . T <*> 0 . DP=21;I16=11,10,0,0,792,30156,0,0,1260,75600,0,0,385,8871,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,137:4:0 0,12,137:4:0 +X 2142 . G <*> 0 . DP=19;I16=11,8,0,0,724,27784,0,0,1140,68400,0,0,385,8919,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,113:3:0 0,12,129:4:0 +X 2143 . T <*> 0 . DP=19;I16=11,8,0,0,650,23454,0,0,1140,68400,0,0,384,8932,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,113:3:0 0,12,120:4:0 +X 2144 . C <*> 0 . DP=19;I16=11,8,0,0,739,29003,0,0,1140,68400,0,0,383,8959,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,108:3:0 0,12,125:4:0 +X 2145 . A <*> 0 . DP=20;I16=12,8,0,0,760,29304,0,0,1200,72000,0,0,381,8951,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,133:4:0 0,12,139:4:0 +X 2146 . G <*> 0 . DP=20;I16=12,8,0,0,745,28105,0,0,1200,72000,0,0,379,8909,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,139:4:0 0,12,127:4:0 +X 2147 . C <*> 0 . DP=20;I16=13,6,0,0,674,24296,0,0,1140,68400,0,0,379,8881,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,127:4:0 0,12,130:4:0 +X 2148 . G <*> 0 . DP=20;I16=12,7,0,0,630,21274,0,0,1140,68400,0,0,365,8537,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,250:11:0 0,12,112:4:0 0,12,120:4:0 +X 2149 . A <*> 0 . DP=20;I16=12,7,0,0,702,26212,0,0,1140,68400,0,0,367,8529,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,138:4:0 0,12,127:4:0 +X 2150 . T <*> 0 . DP=20;I16=13,7,0,0,675,23943,0,0,1200,72000,0,0,383,8713,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,247:11:0 0,12,138:4:0 0,15,139:5:0 +X 2151 . T <*> 0 . DP=20;I16=13,7,0,0,690,24274,0,0,1200,72000,0,0,383,8661,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,251:11:0 0,12,133:4:0 0,15,142:5:0 +X 2152 . G <*> 0 . DP=20;I16=13,7,0,0,693,24713,0,0,1200,72000,0,0,383,8629,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,131:4:0 0,15,146:5:0 +X 2153 . T <*> 0 . DP=19;I16=13,6,0,0,671,24571,0,0,1140,68400,0,0,383,8565,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,230:10:0 0,12,134:4:0 0,15,162:5:0 +X 2154 . C <*> 0 . DP=19;I16=13,6,0,0,703,26955,0,0,1140,68400,0,0,382,8468,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,251:10:0 0,12,131:4:0 0,15,159:5:0 +X 2155 . A <*> 0 . DP=19;I16=13,6,0,0,693,25727,0,0,1140,68400,0,0,381,8389,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,245:10:0 0,12,135:4:0 0,15,156:5:0 +X 2156 . C <*> 0 . DP=19;I16=13,6,0,0,702,26214,0,0,1140,68400,0,0,380,8328,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,125:4:0 0,15,154:5:0 +X 2157 . A <*> 0 . DP=19;I16=13,6,0,0,722,28058,0,0,1140,68400,0,0,379,8285,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,12,141:4:0 0,15,173:5:0 +X 2158 . G <*> 0 . DP=19;I16=13,6,0,0,713,27567,0,0,1140,68400,0,0,378,8260,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,136:4:0 0,15,144:5:0 +X 2159 . G <*> 0 . DP=19;I16=12,6,0,0,662,24744,0,0,1080,64800,0,0,366,8104,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,247:9:0 0,12,126:4:0 0,15,153:5:0 +X 2160 . C <*> 0 . DP=19;I16=12,6,0,0,651,24005,0,0,1080,64800,0,0,364,8038,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,12,119:4:0 0,15,154:5:0 +X 2161 . A <*> 0 . DP=19;I16=13,6,0,0,695,25883,0,0,1140,68400,0,0,369,8005,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,12,121:4:0 0,15,164:5:0 +X 2162 . C <*> 0 . DP=20;I16=13,7,0,0,742,27834,0,0,1200,72000,0,0,365,7911,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,127:4:0 0,15,155:5:0 +X 2163 . T <*> 0 . DP=20;I16=13,7,0,0,763,29517,0,0,1200,72000,0,0,362,7838,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,131:4:0 0,15,175:5:0 +X 2164 . G <*> 0 . DP=20;I16=13,7,0,0,715,26301,0,0,1200,72000,0,0,359,7787,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,116:4:0 0,15,156:5:0 +X 2165 . C <*> 0 . DP=20;I16=13,7,0,0,753,28781,0,0,1200,72000,0,0,355,7709,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,136:4:0 0,15,151:5:0 +X 2166 . T <*> 0 . DP=19;I16=12,7,0,0,711,27211,0,0,1140,68400,0,0,352,7654,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,142:4:0 0,12,140:4:0 +X 2167 . A <*> 0 . DP=19;I16=12,6,0,0,650,23760,0,0,1080,64800,0,0,327,7137,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,12,133:4:0 0,9,111:3:0 +X 2168 . C <*> 0 . DP=19;I16=12,7,0,0,685,25039,0,0,1140,68400,0,0,345,7561,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,130:4:0 0,12,124:4:0 +X 2169 . T <*> 0 . DP=19;I16=12,7,0,0,702,26940,0,0,1140,68400,0,0,341,7525,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,140:4:0 0,12,142:4:0 +X 2170 . C <*> 0 . DP=18;I16=11,7,0,0,665,24861,0,0,1080,64800,0,0,338,7512,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,132:4:0 0,12,135:4:0 +X 2171 . C <*> 0 . DP=20;I16=11,9,0,0,750,28368,0,0,1200,72000,0,0,333,7419,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,136:4:0 0,12,138:4:0 +X 2172 . T <*> 0 . DP=20;I16=11,9,0,0,732,27540,0,0,1200,72000,0,0,330,7346,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,149:4:0 0,12,147:4:0 +X 2173 . G <*> 0 . DP=19;I16=10,9,0,0,704,26534,0,0,1140,68400,0,0,327,7243,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,142:4:0 0,12,133:4:0 +X 2174 . G <*> 0 . DP=19;I16=10,9,0,0,674,24372,0,0,1140,68400,0,0,324,7158,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,126:4:0 0,12,129:4:0 +X 2175 . G <*> 0 . DP=18;I16=9,9,0,0,639,23059,0,0,1080,64800,0,0,322,7090,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,123:4:0 0,12,126:4:0 +X 2176 . G <*> 0 . DP=18;I16=9,9,0,0,621,21815,0,0,1080,64800,0,0,318,6940,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,12,121:4:0 0,12,123:4:0 +X 2177 . T <*> 0 . DP=18;I16=9,9,0,0,547,18051,0,0,1080,64800,0,0,314,6810,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,239:10:0 0,12,83:4:0 0,12,108:4:0 +X 2178 . T <*> 0 . DP=18;I16=9,9,0,0,579,19659,0,0,1080,64800,0,0,310,6700,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,234:10:0 0,12,110:4:0 0,12,118:4:0 +X 2179 . T <*> 0 . DP=18;I16=9,9,0,0,591,20403,0,0,1080,64800,0,0,307,6609,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,239:10:0 0,12,97:4:0 0,12,135:4:0 +X 2180 . T <*> 0 . DP=18;I16=9,9,0,0,616,21524,0,0,1080,64800,0,0,305,6537,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,236:10:0 0,12,122:4:0 0,12,133:4:0 +X 2181 . C <*> 0 . DP=18;I16=9,8,0,0,611,22485,0,0,1020,61200,0,0,293,6385,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,224:9:0 0,12,129:4:0 0,12,150:4:0 +X 2182 . C <*> 0 . DP=18;I16=9,9,0,0,665,24877,0,0,1080,64800,0,0,301,6453,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,125:4:0 0,12,145:4:0 +X 2183 . A <*> 0 . DP=18;I16=9,9,0,0,646,23624,0,0,1080,64800,0,0,299,6441,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,12,123:4:0 0,12,144:4:0 +X 2184 . T <*> 0 . DP=17;I16=8,9,0,0,610,22250,0,0,1020,61200,0,0,298,6448,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,224:9:0 0,12,134:4:0 0,12,136:4:0 +X 2185 . C <*> 0 . DP=16;I16=8,8,0,0,569,20761,0,0,960,57600,0,0,297,6423,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,211:8:0 0,12,128:4:0 0,12,137:4:0 +X 2186 . A <*> 0 . DP=16;I16=8,8,0,0,576,21314,0,0,960,57600,0,0,296,6416,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,204:8:0 0,12,134:4:0 0,12,145:4:0 +X 2187 . A <*> 0 . DP=16;I16=8,8,0,0,562,20396,0,0,960,57600,0,0,295,6427,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,201:8:0 0,12,136:4:0 0,12,135:4:0 +X 2188 . A <*> 0 . DP=17;I16=9,8,0,0,569,19925,0,0,1020,61200,0,0,293,6405,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,214:9:0 0,12,133:4:0 0,12,123:4:0 +X 2189 . C <*> 0 . DP=19;I16=9,10,0,0,645,22647,0,0,1097,65089,0,0,292,6400,0,0;QS=3,0;MQSB=0.934728;MQ0F=0 PL:DP:DV 0,30,230:10:0 0,12,133:4:0 0,15,142:5:0 +X 2190 . C <*> 0 . DP=19;I16=9,10,0,0,604,20072,0,0,1097,65089,0,0,294,6414,0,0;QS=3,0;MQSB=0.934728;MQ0F=0 PL:DP:DV 0,33,238:11:0 0,12,119:4:0 0,12,107:4:0 +X 2191 . C <*> 0 . DP=19;I16=9,10,0,0,647,23007,0,0,1097,65089,0,0,297,6449,0,0;QS=3,0;MQSB=0.934728;MQ0F=0 PL:DP:DV 0,33,251:11:0 0,12,129:4:0 0,12,119:4:0 +X 2192 . T <*> 0 . DP=19;I16=9,10,0,0,659,23723,0,0,1097,65089,0,0,300,6506,0,0;QS=3,0;MQSB=0.934728;MQ0F=0 PL:DP:DV 0,33,253:11:0 0,12,136:4:0 0,12,120:4:0 +X 2193 . C <*> 0 . DP=18;I16=8,10,0,0,642,23934,0,0,1037,61489,0,0,303,6535,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,128:4:0 0,9,87:3:0 +X 2194 . A <*> 0 . DP=18;I16=8,9,0,0,617,22683,0,0,1020,61200,0,0,301,6561,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,12,134:4:0 0,9,98:3:0 +X 2195 . A <*> 0 . DP=18;I16=8,10,0,0,635,23271,0,0,1037,61489,0,0,309,6659,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,128:4:0 0,9,101:3:0 +X 2196 . G <*> 0 . DP=19;I16=8,11,0,0,703,26383,0,0,1097,65089,0,0,312,6754,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,117:4:0 0,12,120:4:0 +X 2197 . A <*> 0 . DP=19;I16=8,11,0,0,735,28599,0,0,1097,65089,0,0,314,6770,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,141:4:0 0,12,125:4:0 +X 2198 . G <*> 0 . DP=19;I16=8,10,0,0,650,24206,0,0,1080,64800,0,0,307,6725,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,129:4:0 0,12,107:4:0 +X 2199 . C <*> 0 . DP=19;I16=8,11,0,0,701,26735,0,0,1097,65089,0,0,318,6862,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,128:4:0 0,12,116:4:0 +X 2200 . T <*> 0 . DP=19;I16=8,11,0,0,710,26768,0,0,1097,65089,0,0,320,6938,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,129:4:0 0,12,114:4:0 +X 2201 . G <*> 0 . DP=17;I16=7,10,0,0,628,23764,0,0,977,57889,0,0,324,7032,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,66:2:0 0,12,119:4:0 +X 2202 . G <*> 0 . DP=17;I16=7,10,0,0,557,19249,0,0,977,57889,0,0,327,7093,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,33,245:11:0 0,6,57:2:0 0,12,115:4:0 +X 2203 . G <*> 0 . DP=17;I16=7,10,0,0,588,21184,0,0,977,57889,0,0,329,7123,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,47:2:0 0,12,116:4:0 +X 2204 . C <*> 0 . DP=17;I16=7,10,0,0,538,18568,0,0,977,57889,0,0,331,7173,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,33,246:11:0 0,6,61:2:0 0,12,99:4:0 +X 2205 . C <*> 0 . DP=18;I16=7,11,0,0,628,22918,0,0,1037,61489,0,0,332,7192,0,0;QS=3,0;MQSB=0.951002;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,68:2:0 0,12,109:4:0 +X 2206 . T <*> 0 . DP=19;I16=7,12,0,0,677,25237,0,0,1097,65089,0,0,334,7230,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,77:2:0 0,12,115:4:0 +X 2207 . G <*> 0 . DP=19;I16=7,11,0,0,663,24717,0,0,1080,64800,0,0,319,6965,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,67:2:0 0,12,110:4:0 +X 2208 . G <*> 0 . DP=21;I16=7,14,0,0,726,26038,0,0,1217,72289,0,0,340,7370,0,0;QS=3,0;MQSB=0.966484;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,110:4:0 0,12,122:4:0 +X 2209 . G <*> 0 . DP=22;I16=8,13,0,0,715,25133,0,0,1237,73369,0,0,325,7075,0,0;QS=3,0;MQSB=0.895122;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,128:5:0 0,12,117:4:0 +X 2210 . G C,<*> 0 . DP=21;I16=7,13,0,1,648,22186,25,625,1177,69769,17,289,331,7165,21,441;QS=2.95442,0.0455764,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.975265;BQB=1;MQ0F=0 PL:DP:DV 0,19,234,33,237,241:12:1 0,15,127,15,127,127:5:0 0,12,113,12,113,113:4:0 +X 2211 . T <*> 0 . DP=21;I16=7,13,0,0,724,27000,0,0,1177,69769,0,0,336,7230,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,141:5:0 0,12,124:4:0 +X 2212 . C <*> 0 . DP=22;I16=8,14,0,0,791,29201,0,0,1254,73658,0,0,364,7850,0,0;QS=3,0;MQSB=0.985548;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,148:5:0 0,12,111:4:0 +X 2213 . A <*> 0 . DP=22;I16=8,14,0,0,767,27327,0,0,1254,73658,0,0,371,8015,0,0;QS=3,0;MQSB=0.985548;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,153:5:0 0,12,112:4:0 +X 2214 . A <*> 0 . DP=22;I16=8,14,0,0,756,26836,0,0,1254,73658,0,0,377,8159,0,0;QS=3,0;MQSB=0.985548;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,153:5:0 0,12,117:4:0 +X 2215 . C <*> 0 . DP=22;I16=8,14,0,0,815,31121,0,0,1254,73658,0,0,381,8229,0,0;QS=3,0;MQSB=0.985548;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,162:5:0 0,12,124:4:0 +X 2216 . T <*> 0 . DP=22;I16=8,14,0,0,815,31233,0,0,1254,73658,0,0,384,8272,0,0;QS=3,0;MQSB=0.985548;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,166:5:0 0,12,124:4:0 +X 2217 . T <*> 0 . DP=22;I16=8,13,0,0,741,26855,0,0,1237,73369,0,0,362,7712,0,0;QS=3,0;MQSB=0.895122;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,155:5:0 0,12,118:4:0 +X 2218 . C <*> 0 . DP=21;I16=7,14,0,0,753,27973,0,0,1194,70058,0,0,391,8423,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,138:4:0 0,12,119:4:0 +X 2219 . C <*> 0 . DP=21;I16=7,13,0,0,757,29125,0,0,1177,69769,0,0,370,7904,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,141:4:0 0,12,122:4:0 +X 2220 . G A,<*> 0 . DP=21;I16=6,2,1,11,256,8364,474,19128,457,26569,720,43200,141,2959,233,5071;QS=0.886504,2.1135,0;VDB=0.532753;SGB=-3.51597;RPB=0.964198;MQB=0.898397;MQSB=0.875769;BQB=0.0354359;MQ0F=0 PL:DP:DV 139,0,130,157,148,255:12:6 69,0,46,75,52,119:4:2 131,12,0,131,12,131:4:4 +X 2221 . G <*> 0 . DP=21;I16=7,13,0,0,738,27922,0,0,1177,69769,0,0,376,8078,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,132:4:0 0,12,120:4:0 +X 2222 . C <*> 0 . DP=21;I16=7,14,0,0,746,28098,0,0,1194,70058,0,0,401,8675,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,135:4:0 0,12,107:4:0 +X 2223 . C <*> 0 . DP=21;I16=7,14,0,0,796,30632,0,0,1194,70058,0,0,401,8671,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,135:4:0 0,12,122:4:0 +X 2224 . T <*> 0 . DP=21;I16=7,14,0,0,811,31599,0,0,1194,70058,0,0,401,8691,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,144:4:0 0,12,123:4:0 +X 2225 . G <*> 0 . DP=21;I16=7,14,0,0,778,29396,0,0,1194,70058,0,0,401,8735,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,133:4:0 0,12,121:4:0 +X 2226 . G <*> 0 . DP=21;I16=7,14,0,0,727,26485,0,0,1194,70058,0,0,401,8803,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,128:4:0 0,12,113:4:0 +X 2227 . G <*> 0 . DP=20;I16=7,12,0,0,663,23985,0,0,1117,66169,0,0,377,8269,0,0;QS=3,0;MQSB=0.879351;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,123:4:0 0,12,114:4:0 +X 2228 . G C,<*> 0 . DP=19;I16=5,12,0,1,643,24791,16,256,1020,61200,17,289,360,8020,25,625;QS=2.9603,0.0397022,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.970092;BQB=1;MQ0F=0 PL:DP:DV 0,17,255,30,255,255:11:1 0,9,95,9,95,95:3:0 0,12,121,12,121,121:4:0 +X 2229 . A <*> 0 . DP=20;I16=6,14,0,0,757,28857,0,0,1134,66458,0,0,406,9138,0,0;QS=3,0;MQSB=0.959189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,138:4:0 0,12,122:4:0 +X 2230 . A <*> 0 . DP=20;I16=6,14,0,0,729,26985,0,0,1134,66458,0,0,409,9291,0,0;QS=3,0;MQSB=0.959189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,141:4:0 0,12,119:4:0 +X 2231 . A <*> 0 . DP=20;I16=6,13,0,0,712,26990,0,0,1117,66169,0,0,386,8790,0,0;QS=3,0;MQSB=0.850016;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,144:4:0 0,12,124:4:0 +X 2232 . C <*> 0 . DP=20;I16=6,14,0,0,751,28657,0,0,1134,66458,0,0,412,9508,0,0;QS=3,0;MQSB=0.959189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,130:4:0 0,12,107:4:0 +X 2233 . T <*> 0 . DP=20;I16=6,14,0,0,774,30432,0,0,1134,66458,0,0,413,9619,0,0;QS=3,0;MQSB=0.959189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,150:4:0 0,12,117:4:0 +X 2234 . G <*> 0 . DP=20;I16=6,14,0,0,719,26621,0,0,1134,66458,0,0,412,9646,0,0;QS=3,0;MQSB=0.959189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,145:4:0 0,12,107:4:0 +X 2235 . G <*> 0 . DP=20;I16=6,14,0,0,728,27036,0,0,1134,66458,0,0,410,9636,0,0;QS=3,0;MQSB=0.959189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,139:4:0 0,12,104:4:0 +X 2236 . G <*> 0 . DP=19;I16=6,13,0,0,705,26985,0,0,1074,62858,0,0,409,9637,0,0;QS=3,0;MQSB=0.965977;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,142:4:0 0,9,84:3:0 +X 2237 . G <*> 0 . DP=19;I16=6,12,0,0,684,26576,0,0,1057,62569,0,0,383,9023,0,0;QS=3,0;MQSB=0.85394;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,141:4:0 0,9,86:3:0 +X 2238 . C <*> 0 . DP=19;I16=5,13,0,0,648,24496,0,0,1037,61489,0,0,381,8993,0,0;QS=3,0;MQSB=0.970092;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,108:3:0 0,9,78:3:0 +X 2239 . A <*> 0 . DP=19;I16=6,11,0,0,634,24178,0,0,997,58969,0,0,373,8935,0,0;QS=3,0;MQSB=0.85832;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,133:4:0 0,6,77:2:0 +X 2240 . A <*> 0 . DP=19;I16=6,13,0,0,731,28595,0,0,1074,62858,0,0,402,9582,0,0;QS=3,0;MQSB=0.965977;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,135:4:0 0,9,101:3:0 +X 2241 . G <*> 0 . DP=19;I16=6,12,0,0,683,26433,0,0,1057,62569,0,0,375,8951,0,0;QS=3,0;MQSB=0.85394;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,126:4:0 0,9,88:3:0 +X 2242 . T <*> 0 . DP=20;I16=5,13,0,0,635,22949,0,0,1057,62569,0,0,370,8944,0,0;QS=3,0;MQSB=0.814433;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,91:3:0 0,9,95:3:0 +X 2243 . A <*> 0 . DP=19;I16=5,14,0,0,704,26274,0,0,1074,62858,0,0,395,9585,0,0;QS=3,0;MQSB=0.933727;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,107:3:0 0,9,99:3:0 +X 2244 . T <*> 0 . DP=19;I16=5,14,0,0,681,25263,0,0,1074,62858,0,0,395,9609,0,0;QS=3,0;MQSB=0.933727;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,89:3:0 0,9,98:3:0 +X 2245 . C <*> 0 . DP=19;I16=5,14,0,0,722,27846,0,0,1074,62858,0,0,394,9592,0,0;QS=3,0;MQSB=0.933727;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,98:3:0 0,9,88:3:0 +X 2246 . A <*> 0 . DP=18;I16=5,12,0,0,597,21693,0,0,997,58969,0,0,367,8861,0,0;QS=3,0;MQSB=0.818731;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,95:3:0 0,6,72:2:0 +X 2247 . C <*> 0 . DP=17;I16=4,13,0,0,639,24373,0,0,954,55658,0,0,391,9391,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,105:3:0 0,6,71:2:0 +X 2248 . C <*> 0 . DP=17;I16=4,13,0,0,669,26863,0,0,954,55658,0,0,390,9306,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,90:3:0 0,6,75:2:0 +X 2249 . A <*> 0 . DP=17;I16=4,13,0,0,677,27371,0,0,954,55658,0,0,389,9231,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,116:3:0 0,6,80:2:0 +X 2250 . G <*> 0 . DP=17;I16=4,13,0,0,654,25800,0,0,954,55658,0,0,388,9166,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,100:3:0 0,6,78:2:0 +X 2251 . A <*> 0 . DP=17;I16=4,13,0,0,673,27327,0,0,954,55658,0,0,387,9111,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,112:3:0 0,6,80:2:0 +X 2252 . G <*> 0 . DP=17;I16=4,12,0,0,647,26249,0,0,937,55369,0,0,361,8441,0,0;QS=3,0;MQSB=0.767432;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,113:3:0 0,6,73:2:0 +X 2253 . A <*> 0 . DP=17;I16=4,13,0,0,641,24643,0,0,954,55658,0,0,385,9031,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,111:3:0 0,6,73:2:0 +X 2254 . T <*> 0 . DP=17;I16=4,12,0,0,615,23821,0,0,937,55369,0,0,358,8332,0,0;QS=3,0;MQSB=0.767432;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,112:3:0 0,6,73:2:0 +X 2255 . G <*> 0 . DP=17;I16=4,13,0,0,677,27243,0,0,954,55658,0,0,380,8844,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,115:3:0 0,6,71:2:0 +X 2256 . A <*> 0 . DP=17;I16=4,13,0,0,656,26088,0,0,954,55658,0,0,377,8741,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,110:3:0 0,6,78:2:0 +X 2257 . G <*> 0 . DP=17;I16=4,12,0,0,627,24863,0,0,937,55369,0,0,349,8023,0,0;QS=3,0;MQSB=0.767432;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,115:3:0 0,6,74:2:0 +X 2258 . C <*> 0 . DP=17;I16=4,13,0,0,667,26403,0,0,954,55658,0,0,371,8565,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,109:3:0 0,6,70:2:0 +X 2259 . T <*> 0 . DP=17;I16=4,13,0,0,646,25334,0,0,954,55658,0,0,368,8492,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,116:3:0 0,6,79:2:0 +X 2260 . T <*> 0 . DP=17;I16=4,13,0,0,638,24178,0,0,954,55658,0,0,365,8429,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,115:3:0 0,6,72:2:0 +X 2261 . T <*> 0 . DP=17;I16=4,13,0,0,633,23799,0,0,954,55658,0,0,362,8376,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,105:3:0 0,6,73:2:0 +X 2262 . A <*> 0 . DP=17;I16=4,13,0,0,628,23438,0,0,954,55658,0,0,359,8333,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,253:12:0 0,9,112:3:0 0,6,74:2:0 +X 2263 . T <*> 0 . DP=17;I16=4,13,0,0,631,23673,0,0,954,55658,0,0,355,8251,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,112:3:0 0,6,74:2:0 +X 2264 . A <*> 0 . DP=17;I16=4,12,0,0,623,24371,0,0,937,55369,0,0,326,7556,0,0;QS=3,0;MQSB=0.767432;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,114:3:0 0,6,75:2:0 +X 2265 . A <*> 0 . DP=18;I16=4,13,0,0,642,24718,0,0,997,58969,0,0,320,7400,0,0;QS=3,0;MQSB=0.762744;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,113:3:0 0,6,75:2:0 +X 2266 . A <*> 0 . DP=19;I16=5,14,0,0,656,23962,0,0,1074,62858,0,0,337,7745,0,0;QS=3,0;MQSB=0.933727;MQ0F=0 PL:DP:DV 0,39,252:13:0 0,12,128:4:0 0,6,75:2:0 +X 2267 . A <*> 0 . DP=20;I16=6,14,0,0,712,26052,0,0,1134,66458,0,0,332,7582,0,0;QS=3,0;MQSB=0.959189;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,134:4:0 0,9,102:3:0 +X 2268 . A <*> 0 . DP=20;I16=6,14,0,0,741,27841,0,0,1134,66458,0,0,327,7391,0,0;QS=3,0;MQSB=0.959189;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,135:4:0 0,9,100:3:0 +X 2269 . T <*> 0 . DP=20;I16=6,13,0,0,681,24751,0,0,1074,62858,0,0,318,7206,0,0;QS=3,0;MQSB=0.965977;MQ0F=0 PL:DP:DV 0,36,246:12:0 0,12,137:4:0 0,9,111:3:0 +X 2270 . A <*> 0 . DP=19;I16=6,12,0,0,652,24154,0,0,1057,62569,0,0,300,6750,0,0;QS=3,0;MQSB=0.85394;MQ0F=0 PL:DP:DV 0,33,244:11:0 0,12,134:4:0 0,9,112:3:0 +X 2271 . A <*> 0 . DP=17;I16=6,11,0,0,654,25406,0,0,954,55658,0,0,316,6944,0,0;QS=3,0;MQSB=0.980001;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,12,142:4:0 0,9,111:3:0 +X 2272 . T <*> 0 . DP=17;I16=6,10,0,0,604,22908,0,0,937,55369,0,0,297,6525,0,0;QS=3,0;MQSB=0.863243;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,12,137:4:0 0,9,111:3:0 +X 2273 . G <*> 0 . DP=17;I16=6,10,0,0,581,22129,0,0,937,55369,0,0,295,6411,0,0;QS=3,0;MQSB=0.863243;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,12,123:4:0 0,9,115:3:0 +X 2274 . G <*> 0 . DP=18;I16=6,11,0,0,621,23109,0,0,997,58969,0,0,293,6313,0,0;QS=3,0;MQSB=0.85832;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,12,132:4:0 0,9,110:3:0 +X 2275 . T <*> 0 . DP=18;I16=6,11,0,0,624,23152,0,0,997,58969,0,0,292,6232,0,0;QS=3,0;MQSB=0.85832;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,12,126:4:0 0,9,113:3:0 +X 2276 . G <*> 0 . DP=20;I16=7,12,0,0,710,26848,0,0,1074,62858,0,0,303,6313,0,0;QS=3,0;MQSB=0.985816;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,129:4:0 0,9,110:3:0 +X 2277 . C <*> 0 . DP=21;I16=8,13,0,0,797,30699,0,0,1194,70058,0,0,303,6247,0,0;QS=3,0;MQSB=0.989565;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,151:5:0 0,12,143:4:0 +X 2278 . T <*> 0 . DP=21;I16=7,13,0,0,736,27790,0,0,1157,68689,0,0,279,5581,0,0;QS=3,0;MQSB=0.962269;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,133:4:0 0,12,148:4:0 +X 2279 . A <*> 0 . DP=20;I16=8,12,0,0,723,27047,0,0,1134,66458,0,0,306,6190,0,0;QS=3,0;MQSB=0.993326;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,155:5:0 0,12,144:4:0 +X 2280 . G <*> 0 . DP=21;I16=8,12,0,0,766,29776,0,0,1177,69769,0,0,299,6085,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,166:5:0 0,12,144:4:0 +X 2281 . C <*> 0 . DP=22;I16=8,13,0,0,784,29748,0,0,1237,73369,0,0,301,6037,0,0;QS=3,0;MQSB=0.895122;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,165:5:0 0,12,140:4:0 +X 2282 . T <*> 0 . DP=22;I16=8,14,0,0,789,29699,0,0,1254,73658,0,0,310,6054,0,0;QS=3,0;MQSB=0.985548;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,162:5:0 0,12,150:4:0 +X 2283 . G <*> 0 . DP=22;I16=8,14,0,0,798,29774,0,0,1254,73658,0,0,312,6054,0,0;QS=3,0;MQSB=0.985548;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,158:5:0 0,12,142:4:0 +X 2284 . G <*> 0 . DP=22;I16=7,14,0,0,760,28408,0,0,1194,70058,0,0,294,5664,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,130:4:0 0,12,141:4:0 +X 2285 . G <*> 0 . DP=23;I16=9,14,0,0,844,31592,0,0,1314,77258,0,0,311,5909,0,0;QS=3,0;MQSB=0.992095;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,152:5:0 0,12,144:4:0 +X 2286 . C <*> 0 . DP=23;I16=9,14,0,0,854,32244,0,0,1314,77258,0,0,311,5869,0,0;QS=3,0;MQSB=0.992095;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,155:5:0 0,12,130:4:0 +X 2287 . A <*> 0 . DP=23;I16=9,14,0,0,818,30288,0,0,1314,77258,0,0,311,5869,0,0;QS=3,0;MQSB=0.992095;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,166:5:0 0,12,143:4:0 +X 2288 . T <*> 0 . DP=22;I16=8,14,0,0,794,29190,0,0,1254,73658,0,0,312,5908,0,0;QS=3,0;MQSB=0.985548;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,158:5:0 0,12,142:4:0 +X 2289 . G <*> 0 . DP=21;I16=8,13,0,0,723,25835,0,0,1237,73369,0,0,314,5984,0,0;QS=3,0;MQSB=0.895122;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,154:5:0 0,12,126:4:0 +X 2290 . G <*> 0 . DP=20;I16=7,13,0,0,748,28318,0,0,1177,69769,0,0,318,6094,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,149:5:0 0,9,114:3:0 +X 2291 . T <*> 0 . DP=20;I16=7,13,0,0,731,27165,0,0,1177,69769,0,0,322,6186,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,151:5:0 0,9,112:3:0 +X 2292 . G <*> 0 . DP=20;I16=7,13,0,0,749,28747,0,0,1177,69769,0,0,325,6259,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,156:5:0 0,9,109:3:0 +X 2293 . G <*> 0 . DP=20;I16=7,13,0,0,739,27903,0,0,1177,69769,0,0,327,6311,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,156:5:0 0,9,112:3:0 +X 2294 . C <*> 0 . DP=21;I16=7,14,0,0,775,29453,0,0,1237,73369,0,0,329,6391,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,169:5:0 0,9,114:3:0 +X 2295 . T <*> 0 . DP=21;I16=7,14,0,0,773,29209,0,0,1237,73369,0,0,331,6451,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,164:5:0 0,9,115:3:0 +X 2296 . T <*> 0 . DP=21;I16=7,14,0,0,756,27780,0,0,1237,73369,0,0,333,6543,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,160:5:0 0,9,106:3:0 +X 2297 . G <*> 0 . DP=20;I16=7,13,0,0,736,27692,0,0,1177,69769,0,0,336,6666,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,165:5:0 0,6,74:2:0 +X 2298 . C <*> 0 . DP=21;I16=7,14,0,0,778,29300,0,0,1237,73369,0,0,339,6819,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,139:5:0 0,9,106:3:0 +X 2299 . A <*> 0 . DP=21;I16=7,14,0,0,714,25282,0,0,1237,73369,0,0,343,7003,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,128:5:0 0,9,110:3:0 +X 2300 . C <*> 0 . DP=21;I16=7,13,0,0,687,24749,0,0,1177,69769,0,0,326,6768,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,148:5:0 0,9,109:3:0 +X 2301 . C <*> 0 . DP=23;I16=7,15,0,0,802,30292,0,0,1266,74210,0,0,349,7363,0,0;QS=3,0;MQSB=0.970024;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,147:5:0 0,9,116:3:0 +X 2302 . T <*> 0 . DP=23;I16=7,16,0,0,860,32956,0,0,1326,77810,0,0,354,7496,0,0;QS=3,0;MQSB=0.964916;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,166:5:0 0,12,150:4:0 +X 2303 . G <*> 0 . DP=23;I16=7,16,0,0,817,29823,0,0,1326,77810,0,0,356,7604,0,0;QS=3,0;MQSB=0.964916;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,151:5:0 0,12,139:4:0 +X 2304 . T <*> 0 . DP=23;I16=7,16,0,0,802,28628,0,0,1326,77810,0,0,357,7691,0,0;QS=3,0;MQSB=0.964916;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,148:5:0 0,12,140:4:0 +X 2305 . A <*> 0 . DP=22;I16=7,14,0,0,725,25585,0,0,1237,73369,0,0,355,7791,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,36,248:12:0 0,15,155:5:0 0,12,129:4:0 +X 2306 . A <*> 0 . DP=21;I16=7,14,0,0,727,26841,0,0,1206,70610,0,0,361,7899,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,36,246:12:0 0,15,168:5:0 0,12,130:4:0 +X 2307 . T <*> 0 . DP=21;I16=7,14,0,0,751,27427,0,0,1206,70610,0,0,362,7964,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,36,251:12:0 0,15,165:5:0 0,12,141:4:0 +X 2308 . C <*> 0 . DP=21;I16=7,14,0,0,735,26675,0,0,1206,70610,0,0,363,8051,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,144:5:0 0,12,146:4:0 +X 2309 . C A,<*> 0 . DP=19;I16=7,11,0,1,604,21364,16,256,1057,62569,29,841,358,8094,8,64;QS=2.95676,0.0432432,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.985816;BQB=1;MQ0F=0 PL:DP:DV 0,20,224,33,227,230:12:1 0,9,94,9,94,94:3:0 0,12,138,12,138,138:4:0 +X 2310 . C <*> 0 . DP=18;I16=6,12,0,0,668,25392,0,0,1049,62041,0,0,370,8282,0,0;QS=3,0;MQSB=0.961295;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,80:2:0 0,12,139:4:0 +X 2311 . A <*> 0 . DP=19;I16=7,12,0,0,707,26855,0,0,1109,65641,0,0,373,8371,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,78:2:0 0,12,137:4:0 +X 2312 . G <*> 0 . DP=20;I16=7,12,0,0,736,29118,0,0,1109,65641,0,0,364,8306,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,82:2:0 0,9,122:3:0 +X 2313 . C <*> 0 . DP=20;I16=7,13,0,0,723,27231,0,0,1169,69241,0,0,382,8596,0,0;QS=3,0;MQSB=0.962269;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,76:2:0 0,12,130:4:0 +X 2314 . A <*> 0 . DP=21;I16=7,12,0,0,630,22184,0,0,1109,65641,0,0,372,8510,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,78:2:0 0,9,115:3:0 +X 2315 . C <*> 0 . DP=23;I16=7,14,0,0,739,26861,0,0,1229,72841,0,0,392,8892,0,0;QS=3,0;MQSB=0.966484;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,71:2:0 0,12,135:4:0 +X 2316 . T <*> 0 . DP=23;I16=8,15,0,0,826,30690,0,0,1349,80041,0,0,408,9102,0,0;QS=3,0;MQSB=0.967216;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,105:3:0 0,15,170:5:0 +X 2317 . T <*> 0 . DP=24;I16=7,16,0,0,766,27014,0,0,1349,80041,0,0,411,9211,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,78:2:0 0,15,170:5:0 +X 2318 . T <*> 0 . DP=24;I16=8,14,0,0,757,27433,0,0,1320,79200,0,0,379,8449,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,91:3:0 0,15,165:5:0 +X 2319 . G <*> 0 . DP=24;I16=6,16,0,0,827,31577,0,0,1289,76441,0,0,398,8882,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,43:1:0 0,15,167:5:0 +X 2320 . G <*> 0 . DP=23;I16=7,16,0,0,803,29077,0,0,1349,80041,0,0,435,9675,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,87:3:0 0,15,157:5:0 +X 2321 . G <*> 0 . DP=23;I16=7,16,0,0,804,29368,0,0,1349,80041,0,0,442,9840,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,79:3:0 0,15,169:5:0 +X 2322 . A <*> 0 . DP=24;I16=7,17,0,0,860,32116,0,0,1409,83641,0,0,449,10027,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,95:3:0 0,15,178:5:0 +X 2323 . G <*> 0 . DP=24;I16=7,17,0,0,863,31887,0,0,1409,83641,0,0,457,10237,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,88:3:0 0,15,153:5:0 +X 2324 . G <*> 0 . DP=24;I16=7,16,0,0,786,27932,0,0,1349,80041,0,0,462,10416,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,88:3:0 0,15,161:5:0 +X 2325 . C <*> 0 . DP=24;I16=7,15,0,0,730,25576,0,0,1289,76441,0,0,427,9625,0,0;QS=3,0;MQSB=0.970024;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,102:3:0 0,12,130:4:0 +X 2326 . C <*> 0 . DP=24;I16=7,15,0,0,709,23523,0,0,1320,79200,0,0,426,9498,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,241:15:0 0,9,95:3:0 0,12,133:4:0 +X 2327 . G <*> 0 . DP=24;I16=7,17,0,0,817,29275,0,0,1409,83641,0,0,481,10891,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,81:3:0 0,15,158:5:0 +X 2328 . A <*> 0 . DP=24;I16=6,17,0,0,814,29804,0,0,1349,80041,0,0,461,10427,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,82:3:0 0,15,172:5:0 +X 2329 . G <*> 0 . DP=23;I16=6,16,0,0,755,27641,0,0,1289,76441,0,0,477,11005,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,63:2:0 0,15,160:5:0 +X 2330 . C <*> 0 . DP=24;I16=7,17,0,0,875,33131,0,0,1409,83641,0,0,498,11424,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,87:3:0 0,18,181:6:0 +X 2331 . T <*> 0 . DP=24;I16=7,17,0,0,862,31882,0,0,1409,83641,0,0,505,11635,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,106:3:0 0,18,200:6:0 +X 2332 . A <*> 0 . DP=25;I16=8,17,0,0,926,35412,0,0,1469,87241,0,0,512,11864,0,0;QS=3,0;MQSB=0.973216;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,97:3:0 0,18,204:6:0 +X 2333 . G <*> 0 . DP=26;I16=8,17,0,0,923,35129,0,0,1469,87241,0,0,494,11436,0,0;QS=3,0;MQSB=0.973216;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,97:3:0 0,18,189:6:0 +X 2334 . G <*> 0 . DP=26;I16=8,18,0,0,928,34574,0,0,1529,90841,0,0,527,12277,0,0;QS=3,0;MQSB=0.975611;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,93:3:0 0,21,202:7:0 +X 2335 . A <*> 0 . DP=26;I16=8,18,0,0,967,36793,0,0,1529,90841,0,0,535,12513,0,0;QS=3,0;MQSB=0.975611;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,105:3:0 0,21,214:7:0 +X 2336 . G <*> 0 . DP=26;I16=8,18,0,0,962,36346,0,0,1529,90841,0,0,543,12769,0,0;QS=3,0;MQSB=0.975611;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,92:3:0 0,21,204:7:0 +X 2337 . G <*> 0 . DP=26;I16=7,18,0,0,895,32981,0,0,1469,87241,0,0,527,12465,0,0;QS=3,0;MQSB=0.977814;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,74:2:0 0,21,204:7:0 +X 2338 . A <*> 0 . DP=26;I16=8,18,0,0,892,31758,0,0,1529,90841,0,0,556,13186,0,0;QS=3,0;MQSB=0.975611;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,87:3:0 0,21,194:7:0 +X 2339 . T <*> 0 . DP=26;I16=7,18,0,0,827,28921,0,0,1469,87241,0,0,537,12769,0,0;QS=3,0;MQSB=0.977814;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,55:2:0 0,21,200:7:0 +X 2340 . C <*> 0 . DP=25;I16=7,18,0,0,792,25816,0,0,1469,87241,0,0,541,12893,0,0;QS=3,0;MQSB=0.977814;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,57:2:0 0,21,173:7:0 +X 2341 . G <*> 0 . DP=25;I16=6,17,0,0,771,26477,0,0,1349,80041,0,0,494,11732,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,3,41:1:0 0,21,186:7:0 +X 2342 . T <*> 0 . DP=24;I16=6,17,0,0,863,32711,0,0,1349,80041,0,0,523,12459,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,3,43:1:0 0,21,214:7:0 +X 2343 . T <*> 0 . DP=24;I16=6,16,0,0,770,28230,0,0,1289,76441,0,0,504,12032,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,44:1:0 0,21,213:7:0 +X 2344 . T <*> 0 . DP=24;I16=7,17,0,0,843,30483,0,0,1409,83641,0,0,552,13124,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,56:2:0 0,21,202:7:0 +X 2345 . G <*> 0 . DP=24;I16=7,17,0,0,897,34121,0,0,1409,83641,0,0,554,13162,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,77:2:0 0,21,206:7:0 +X 2346 . A <*> 0 . DP=24;I16=7,17,0,0,908,34818,0,0,1409,83641,0,0,556,13212,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,68:2:0 0,21,220:7:0 +X 2347 . G <*> 0 . DP=24;I16=6,17,0,0,824,30406,0,0,1349,80041,0,0,533,12649,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,3,39:1:0 0,21,190:7:0 +X 2348 . T <*> 0 . DP=24;I16=7,16,0,0,745,25653,0,0,1349,80041,0,0,544,13072,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,64:2:0 0,18,183:6:0 +X 2349 . C <*> 0 . DP=24;I16=6,17,0,0,804,29224,0,0,1349,80041,0,0,534,12656,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,3,36:1:0 0,21,200:7:0 +X 2350 . C <*> 0 . DP=25;I16=7,17,0,0,869,31905,0,0,1409,83641,0,0,534,12652,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,63:2:0 0,21,198:7:0 +X 2351 . A <*> 0 . DP=25;I16=8,17,0,0,945,36169,0,0,1469,87241,0,0,559,13237,0,0;QS=3,0;MQSB=0.973216;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,74:2:0 0,21,222:7:0 +X 2352 . G <*> 0 . DP=25;I16=7,17,0,0,893,34005,0,0,1409,83641,0,0,533,12539,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,41:1:0 0,21,207:7:0 +X 2353 . C <*> 0 . DP=24;I16=7,17,0,0,866,31864,0,0,1409,83641,0,0,531,12435,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,41:1:0 0,21,205:7:0 +X 2354 . A <*> 0 . DP=24;I16=7,17,0,0,880,33206,0,0,1409,83641,0,0,529,12351,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,43:1:0 0,21,214:7:0 +X 2355 . G <*> 0 . DP=24;I16=7,17,0,0,871,32261,0,0,1409,83641,0,0,526,12238,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,39:1:0 0,21,195:7:0 +X 2356 . T <*> 0 . DP=24;I16=7,17,0,0,887,33305,0,0,1409,83641,0,0,521,12047,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,43:1:0 0,21,219:7:0 +X 2357 . T <*> 0 . DP=24;I16=7,17,0,0,899,34225,0,0,1409,83641,0,0,516,11878,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,43:1:0 0,21,220:7:0 +X 2358 . T <*> 0 . DP=24;I16=7,17,0,0,913,34891,0,0,1409,83641,0,0,510,11680,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,40:1:0 0,21,218:7:0 +X 2359 . G <*> 0 . DP=25;I16=7,17,0,0,898,34048,0,0,1409,83641,0,0,503,11451,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,39:1:0 0,21,209:7:0 +X 2360 . A <*> 0 . DP=25;I16=7,18,0,0,959,37113,0,0,1469,87241,0,0,514,11552,0,0;QS=3,0;MQSB=0.977814;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,72:2:0 0,21,222:7:0 +X 2361 . G <*> 0 . DP=25;I16=7,17,0,0,850,30946,0,0,1409,83641,0,0,482,10726,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,67:2:0 0,18,168:6:0 +X 2362 . A <*> 0 . DP=25;I16=7,17,0,0,762,25482,0,0,1409,83641,0,0,475,10547,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,51:2:0 0,18,159:6:0 +X 2363 . C <*> 0 . DP=25;I16=7,18,0,0,875,31837,0,0,1469,87241,0,0,493,11015,0,0;QS=3,0;MQSB=0.977814;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,65:2:0 0,21,187:7:0 +X 2364 . C <*> 0 . DP=25;I16=7,18,0,0,927,34965,0,0,1469,87241,0,0,486,10880,0,0;QS=3,0;MQSB=0.977814;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,64:2:0 0,21,201:7:0 +X 2365 . A <*> 0 . DP=24;I16=7,17,0,0,908,34754,0,0,1409,83641,0,0,479,10717,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,65:2:0 0,21,221:7:0 +X 2366 . G <*> 0 . DP=25;I16=7,17,0,0,912,35074,0,0,1440,86400,0,0,447,9951,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,58:2:0 0,21,206:7:0 +X 2367 . C <*> 0 . DP=25;I16=7,17,0,0,872,32088,0,0,1409,83641,0,0,440,9782,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,36:1:0 0,21,197:7:0 +X 2368 . C <*> 0 . DP=24;I16=6,17,0,0,871,33801,0,0,1349,80041,0,0,434,9634,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,39:1:0 0,18,180:6:0 +X 2369 . T <*> 0 . DP=24;I16=6,18,0,0,877,33009,0,0,1409,83641,0,0,452,10082,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,49:2:0 0,18,179:6:0 +X 2370 . G <*> 0 . DP=24;I16=6,18,0,0,899,34289,0,0,1409,83641,0,0,445,9927,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,56:2:0 0,18,179:6:0 +X 2371 . G <*> 0 . DP=24;I16=6,18,0,0,880,33088,0,0,1409,83641,0,0,438,9794,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,51:2:0 0,18,177:6:0 +X 2372 . C <*> 0 . DP=24;I16=6,18,0,0,827,29615,0,0,1409,83641,0,0,431,9683,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,47:2:0 0,18,163:6:0 +X 2373 . C <*> 0 . DP=24;I16=6,18,0,0,886,33212,0,0,1409,83641,0,0,424,9594,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,58:2:0 0,18,166:6:0 +X 2374 . A <*> 0 . DP=23;I16=6,17,0,0,844,31230,0,0,1349,80041,0,0,417,9477,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,66:2:0 0,18,177:6:0 +X 2375 . A <*> 0 . DP=23;I16=5,17,0,0,788,28340,0,0,1289,76441,0,0,409,9333,0,0;QS=3,0;MQSB=0.981001;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,64:2:0 0,18,171:6:0 +X 2376 . T <*> 0 . DP=22;I16=5,17,0,0,778,27804,0,0,1289,76441,0,0,401,9161,0,0;QS=3,0;MQSB=0.981001;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,62:2:0 0,18,162:6:0 +X 2377 . A <*> 0 . DP=21;I16=4,17,0,0,704,24488,0,0,1229,72841,0,0,394,9008,0,0;QS=3,0;MQSB=0.984085;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,49:2:0 0,15,135:5:0 +X 2378 . C <*> 0 . DP=20;I16=4,16,0,0,626,20138,0,0,1169,69241,0,0,388,8872,0,0;QS=3,0;MQSB=0.982301;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,15:1:0 0,15,108:5:0 +X 2379 . G <*> 0 . DP=20;I16=4,16,0,0,714,25924,0,0,1169,69241,0,0,382,8752,0,0;QS=3,0;MQSB=0.982301;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,34:1:0 0,15,140:5:0 +X 2380 . G <*> 0 . DP=19;I16=4,14,0,0,672,25672,0,0,1049,62041,0,0,352,8022,0,0;QS=3,0;MQSB=0.977696;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,18:1:0 0,15,134:5:0 +X 2381 . C <*> 0 . DP=18;I16=4,14,0,0,676,25626,0,0,1049,62041,0,0,373,8555,0,0;QS=3,0;MQSB=0.977696;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,28:1:0 0,15,133:5:0 +X 2382 . A <*> 0 . DP=19;I16=5,14,0,0,669,23995,0,0,1109,65641,0,0,369,8475,0,0;QS=3,0;MQSB=0.97357;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,28:1:0 0,15,131:5:0 +X 2383 . A <*> 0 . DP=19;I16=5,14,0,0,686,25162,0,0,1109,65641,0,0,365,8359,0,0;QS=3,0;MQSB=0.97357;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,26:1:0 0,15,140:5:0 +X 2384 . A <*> 0 . DP=19;I16=5,14,0,0,649,22943,0,0,1109,65641,0,0,360,8210,0,0;QS=3,0;MQSB=0.97357;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,13:1:0 0,15,132:5:0 +X 2385 . A <*> 0 . DP=18;I16=4,14,0,0,643,23235,0,0,1049,62041,0,0,356,8078,0,0;QS=3,0;MQSB=0.977696;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,38:1:0 0,15,134:5:0 +X 2386 . C <*> 0 . DP=18;I16=4,14,0,0,652,24008,0,0,1049,62041,0,0,351,7913,0,0;QS=3,0;MQSB=0.977696;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,25:1:0 0,15,130:5:0 +X 2387 . C <*> 0 . DP=18;I16=4,14,0,0,667,25007,0,0,1049,62041,0,0,345,7717,0,0;QS=3,0;MQSB=0.977696;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,25:1:0 0,15,128:5:0 +X 2388 . C <*> 0 . DP=18;I16=4,14,0,0,691,26659,0,0,1049,62041,0,0,339,7541,0,0;QS=3,0;MQSB=0.977696;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,39:1:0 0,15,134:5:0 +X 2389 . A <*> 0 . DP=19;I16=5,14,0,0,682,24912,0,0,1109,65641,0,0,333,7385,0,0;QS=3,0;MQSB=0.97357;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,35:1:0 0,15,140:5:0 +X 2390 . G <*> 0 . DP=18;I16=5,13,0,0,642,23418,0,0,1049,62041,0,0,328,7200,0,0;QS=3,0;MQSB=0.970092;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,27:1:0 0,15,126:5:0 +X 2391 . T <*> 0 . DP=18;I16=5,12,0,0,624,23122,0,0,989,58441,0,0,298,6412,0,0;QS=2,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,0,0:0:0 0,15,140:5:0 +X 2392 . C <*> 0 . DP=18;I16=5,12,0,0,660,25910,0,0,989,58441,0,0,291,6171,0,0;QS=2,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,0,0:0:0 0,15,131:5:0 +X 2393 . T <*> 0 . DP=18;I16=5,13,0,0,669,25099,0,0,1049,62041,0,0,309,6577,0,0;QS=3,0;MQSB=0.970092;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,38:1:0 0,15,134:5:0 +X 2394 . C <*> 0 . DP=17;I16=5,12,0,0,653,25323,0,0,989,58441,0,0,303,6379,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,29:1:0 0,15,133:5:0 +X 2395 . T <*> 0 . DP=17;I16=5,12,0,0,613,22621,0,0,989,58441,0,0,297,6201,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,19:1:0 0,15,128:5:0 +X 2396 . A <*> 0 . DP=17;I16=5,11,0,0,584,21426,0,0,929,54841,0,0,266,5418,0,0;QS=2,0;MQSB=0.960687;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,0,0:0:0 0,15,130:5:0 +X 2397 . C <*> 0 . DP=18;I16=5,13,0,0,650,24046,0,0,1049,62041,0,0,284,5856,0,0;QS=3,0;MQSB=0.970092;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,18:1:0 0,15,129:5:0 +X 2398 . A <*> 0 . DP=18;I16=5,13,0,0,617,21907,0,0,1049,62041,0,0,278,5692,0,0;QS=3,0;MQSB=0.970092;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,19:1:0 0,15,128:5:0 +X 2399 . A <*> 0 . DP=17;I16=5,11,0,0,592,22176,0,0,929,54841,0,0,248,4926,0,0;QS=2,0;MQSB=0.960687;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,0,0:0:0 0,12,115:4:0 +X 2400 . A <*> 0 . DP=16;I16=5,11,0,0,576,21010,0,0,929,54841,0,0,269,5431,0,0;QS=3,0;MQSB=0.960687;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,26:1:0 0,9,99:3:0 +X 2401 . A <*> 0 . DP=17;I16=6,11,0,0,594,21126,0,0,989,58441,0,0,265,5331,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,23:1:0 0,9,98:3:0 +X 2402 . A <*> 0 . DP=17;I16=6,11,0,0,606,21986,0,0,989,58441,0,0,262,5252,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,27:1:0 0,9,99:3:0 +X 2403 . A <*> 0 . DP=17;I16=6,11,0,0,608,22130,0,0,989,58441,0,0,259,5195,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,21:1:0 0,9,97:3:0 +X 2404 . T <*> 0 . DP=17;I16=6,11,0,0,567,19449,0,0,989,58441,0,0,256,5160,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,14:1:0 0,9,87:3:0 +X 2405 . A <*> 0 . DP=18;I16=7,11,0,0,618,21666,0,0,1049,62041,0,0,253,5147,0,0;QS=3,0;MQSB=0.951002;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,17:1:0 0,9,88:3:0 +X 2406 . C <*> 0 . DP=18;I16=7,11,0,0,676,25664,0,0,1049,62041,0,0,250,5108,0,0;QS=3,0;MQSB=0.951002;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,27:1:0 0,9,90:3:0 +X 2407 . A <*> 0 . DP=19;I16=8,11,0,0,673,24197,0,0,1109,65641,0,0,246,5046,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,3,34:1:0 0,9,89:3:0 +X 2408 . A <*> 0 . DP=18;I16=8,10,0,0,619,21951,0,0,1049,62041,0,0,243,4961,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,3,22:1:0 0,6,73:2:0 +X 2409 . A <*> 0 . DP=17;I16=8,9,0,0,615,22687,0,0,1020,61200,0,0,240,4852,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,39:1:0 0,6,74:2:0 +X 2410 . A <*> 0 . DP=17;I16=8,9,0,0,604,21938,0,0,1020,61200,0,0,237,4769,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,39:1:0 0,6,73:2:0 +X 2411 . A <*> 0 . DP=16;I16=7,9,0,0,567,20551,0,0,960,57600,0,0,235,4711,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,25:1:0 0,6,70:2:0 +X 2412 . A <*> 0 . DP=15;I16=7,8,0,0,527,18903,0,0,900,54000,0,0,234,4676,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,21:1:0 0,6,70:2:0 +X 2413 . C <*> 0 . DP=15;I16=7,8,0,0,559,21161,0,0,900,54000,0,0,233,4663,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,22:1:0 0,6,72:2:0 +X 2414 . A <*> 0 . DP=16;I16=8,8,0,0,570,20822,0,0,929,54841,0,0,232,4672,0,0;QS=3,0;MQSB=0.915545;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,25:1:0 0,6,73:2:0 +X 2415 . A <*> 0 . DP=16;I16=9,7,0,0,574,20768,0,0,929,54841,0,0,232,4652,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,30:1:0 0,6,64:2:0 +X 2416 . C <*> 0 . DP=17;I16=8,8,0,0,576,21424,0,0,960,57600,0,0,231,4649,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,42:2:0 0,6,68:2:0 +X 2417 . T <*> 0 . DP=17;I16=10,7,0,0,612,22740,0,0,958,55682,0,0,235,4627,0,0;QS=3,0;MQSB=0.79189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,57:2:0 0,9,92:3:0 +X 2418 . A <*> 0 . DP=17;I16=10,7,0,0,624,23210,0,0,958,55682,0,0,238,4626,0,0;QS=3,0;MQSB=0.79189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,62:2:0 0,9,105:3:0 +X 2419 . G <*> 0 . DP=19;I16=11,7,0,0,651,24113,0,0,1018,59282,0,0,241,4651,0,0;QS=3,0;MQSB=0.817948;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,51:2:0 0,12,126:4:0 +X 2420 . C <*> 0 . DP=19;I16=11,8,0,0,663,23999,0,0,1078,62882,0,0,246,4704,0,0;QS=3,0;MQSB=0.803979;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,44:2:0 0,12,127:4:0 +X 2421 . C <*> 0 . DP=19;I16=10,8,0,0,657,24779,0,0,1049,62041,0,0,244,4738,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,45:2:0 0,12,126:4:0 +X 2422 . A <*> 0 . DP=18;I16=11,6,0,0,647,24747,0,0,958,55682,0,0,238,4538,0,0;QS=3,0;MQSB=0.833753;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,33:1:0 0,12,137:4:0 +X 2423 . G <*> 0 . DP=18;I16=11,6,0,0,634,24250,0,0,958,55682,0,0,258,4972,0,0;QS=3,0;MQSB=0.833753;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,54:2:0 0,12,126:4:0 +X 2424 . G <*> 0 . DP=18;I16=10,6,0,0,595,22361,0,0,929,54841,0,0,240,4714,0,0;QS=3,0;MQSB=0.948436;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,36:1:0 0,12,126:4:0 +X 2425 . C <*> 0 . DP=18;I16=10,7,0,0,596,21716,0,0,989,58441,0,0,260,5074,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,45:2:0 0,12,114:4:0 +X 2426 . G <*> 0 . DP=18;I16=10,7,0,0,550,18088,0,0,989,58441,0,0,263,5171,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,33,232:11:0 0,6,59:2:0 0,12,113:4:0 +X 2427 . T <*> 0 . DP=18;I16=11,6,0,0,618,22654,0,0,958,55682,0,0,275,5403,0,0;QS=3,0;MQSB=0.833753;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,62:2:0 0,9,99:3:0 +X 2428 . G <*> 0 . DP=18;I16=11,7,0,0,649,24633,0,0,1018,59282,0,0,281,5535,0,0;QS=3,0;MQSB=0.817948;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,48:2:0 0,12,128:4:0 +X 2429 . G <*> 0 . DP=18;I16=10,7,0,0,553,19057,0,0,989,58441,0,0,269,5459,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,33,241:11:0 0,6,55:2:0 0,12,117:4:0 +X 2430 . T A,<*> 0 . DP=18;I16=10,7,1,0,552,18556,21,441,989,58441,29,841,271,5603,16,256;QS=2.94278,0.0572207,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.817948;BQB=1;MQ0F=0 PL:DP:DV 0,15,212,33,215,222:12:1 0,6,60,6,60,60:2:0 0,12,125,12,125,125:4:0 +X 2431 . G <*> 0 . DP=18;I16=11,5,0,0,580,21766,0,0,898,52082,0,0,268,5764,0,0;QS=3,0;MQSB=0.851779;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,37:1:0 0,9,98:3:0 +X 2432 . G <*> 0 . DP=17;I16=10,7,0,0,593,21479,0,0,958,55682,0,0,295,6179,0,0;QS=3,0;MQSB=0.79189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,53:2:0 0,9,97:3:0 +X 2433 . T <*> 0 . DP=17;I16=10,7,0,0,577,20425,0,0,958,55682,0,0,299,6321,0,0;QS=3,0;MQSB=0.79189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,57:2:0 0,9,94:3:0 +X 2434 . G <*> 0 . DP=17;I16=10,6,0,0,546,19340,0,0,929,54841,0,0,284,6082,0,0;QS=3,0;MQSB=0.948436;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,46:2:0 0,6,62:2:0 +X 2435 . C <*> 0 . DP=18;I16=12,5,0,0,597,21843,0,0,958,55682,0,0,304,6626,0,0;QS=3,0;MQSB=0.870325;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,58:2:0 0,6,60:2:0 +X 2436 . A <*> 0 . DP=18;I16=11,6,0,0,545,18599,0,0,989,58441,0,0,295,6379,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,64:3:0 0,6,61:2:0 +X 2437 . C <*> 0 . DP=18;I16=11,5,0,0,573,21195,0,0,929,54841,0,0,297,6541,0,0;QS=3,0;MQSB=0.960687;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,63:2:0 0,6,63:2:0 +X 2438 . A <*> 0 . DP=19;I16=12,6,0,0,583,20111,0,0,1018,59282,0,0,328,7322,0,0;QS=3,0;MQSB=0.85394;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,65:2:0 0,6,65:2:0 +X 2439 . C <*> 0 . DP=19;I16=11,7,0,0,635,22997,0,0,1049,62041,0,0,314,6974,0,0;QS=3,0;MQSB=0.951002;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,91:3:0 0,6,57:2:0 +X 2440 . C <*> 0 . DP=21;I16=13,7,0,0,701,26195,0,0,1138,66482,0,0,346,7840,0,0;QS=3,0;MQSB=0.857404;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,114:4:0 0,6,66:2:0 +X 2441 . T <*> 0 . DP=21;I16=13,8,0,0,788,29910,0,0,1198,70082,0,0,360,8068,0,0;QS=3,0;MQSB=0.845496;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,164:5:0 0,6,67:2:0 +X 2442 . G <*> 0 . DP=20;I16=12,7,0,0,695,25957,0,0,1109,65641,0,0,342,7596,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,128:4:0 0,6,66:2:0 +X 2443 . T <*> 0 . DP=20;I16=13,7,0,0,697,24685,0,0,1138,66482,0,0,373,8345,0,0;QS=3,0;MQSB=0.857404;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,130:4:0 0,6,64:2:0 +X 2444 . A <*> 0 . DP=21;I16=13,8,0,0,755,27981,0,0,1198,70082,0,0,379,8489,0,0;QS=3,0;MQSB=0.845496;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,140:4:0 0,6,64:2:0 +X 2445 . G <*> 0 . DP=21;I16=12,8,0,0,731,27427,0,0,1169,69241,0,0,359,7927,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,130:4:0 0,6,65:2:0 +X 2446 . T <*> 0 . DP=21;I16=13,8,0,0,723,25707,0,0,1198,70082,0,0,389,8633,0,0;QS=3,0;MQSB=0.845496;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,128:4:0 0,6,65:2:0 +X 2447 . C <*> 0 . DP=22;I16=14,8,0,0,770,27950,0,0,1258,73682,0,0,394,8732,0,0;QS=3,0;MQSB=0.86151;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,127:4:0 0,6,64:2:0 +X 2448 . C <*> 0 . DP=23;I16=14,7,0,0,727,26165,0,0,1167,67323,0,0,388,8674,0,0;QS=3,0;MQSB=0.735784;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,129:5:0 0,6,66:2:0 +X 2449 . C <*> 0 . DP=23;I16=13,8,0,0,727,26415,0,0,1198,70082,0,0,363,7787,0,0;QS=3,0;MQSB=0.845496;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,128:5:0 0,6,62:2:0 +X 2450 . A <*> 0 . DP=22;I16=12,8,0,0,673,24267,0,0,1138,66482,0,0,371,7959,0,0;QS=3,0;MQSB=0.826565;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,143:5:0 0,6,65:2:0 +X 2451 . G <*> 0 . DP=22;I16=14,8,0,0,821,31595,0,0,1227,70923,0,0,429,9401,0,0;QS=3,0;MQSB=0.715049;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,151:5:0 0,6,67:2:0 +X 2452 . C <*> 0 . DP=22;I16=14,8,0,0,743,26557,0,0,1227,70923,0,0,437,9613,0,0;QS=3,0;MQSB=0.715049;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,137:5:0 0,6,66:2:0 +X 2453 . T <*> 0 . DP=22;I16=14,8,0,0,775,28215,0,0,1227,70923,0,0,445,9845,0,0;QS=3,0;MQSB=0.715049;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,143:5:0 0,6,68:2:0 +X 2454 . A <*> 0 . DP=22;I16=14,8,0,0,721,24545,0,0,1227,70923,0,0,453,10097,0,0;QS=3,0;MQSB=0.715049;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,145:5:0 0,6,64:2:0 +X 2455 . C <*> 0 . DP=22;I16=14,8,0,0,776,28212,0,0,1227,70923,0,0,461,10369,0,0;QS=3,0;MQSB=0.715049;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,138:5:0 0,6,65:2:0 +X 2456 . T <*> 0 . DP=24;I16=14,9,0,0,834,30902,0,0,1318,77282,0,0,444,10036,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,168:6:0 0,6,60:2:0 +X 2457 . C <*> 0 . DP=24;I16=15,9,0,0,816,29244,0,0,1347,78123,0,0,478,10924,0,0;QS=3,0;MQSB=0.72325;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,159:6:0 0,6,65:2:0 +X 2458 . A <*> 0 . DP=24;I16=15,9,0,0,869,32555,0,0,1347,78123,0,0,487,11209,0,0;QS=3,0;MQSB=0.72325;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,166:6:0 0,6,65:2:0 +X 2459 . G T,<*> 0 . DP=24;I16=13,9,1,0,822,31186,13,169,1289,76441,29,841,453,10551,17,289;QS=2.92973,0.0702703,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.851535;BQB=1;MQ0F=0 PL:DP:DV 0,45,255,45,255,255:15:0 0,5,138,15,141,144:6:1 0,6,64,6,64,64:2:0 +X 2460 . G <*> 0 . DP=24;I16=14,9,0,0,834,31432,0,0,1318,77282,0,0,477,11065,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,160:6:0 0,6,65:2:0 +X 2461 . A G,<*> 0 . DP=24;I16=14,9,1,0,839,31487,13,169,1318,77282,29,841,489,11521,19,361;QS=2.93401,0.0659898,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.72325;BQB=1;MQ0F=0 PL:DP:DV 0,48,255,48,255,255:16:0 0,5,148,15,151,154:6:1 0,6,67,6,67,67:2:0 +X 2462 . G <*> 0 . DP=25;I16=15,10,0,0,893,33155,0,0,1407,81723,0,0,514,12090,0,0;QS=3,0;MQSB=0.707404;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,165:6:0 0,6,66:2:0 +X 2463 . G T,<*> 0 . DP=25;I16=12,10,1,0,777,28525,14,196,1289,76441,29,841,452,10720,25,625;QS=2.975,0.025,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.825053;BQB=1;MQ0F=0 PL:DP:DV 0,36,255,48,255,255:17:1 0,12,133,12,133,133:4:0 0,6,68,6,68,68:2:0 +X 2464 . C <*> 0 . DP=25;I16=15,10,0,0,904,34194,0,0,1407,81723,0,0,526,12458,0,0;QS=3,0;MQSB=0.707404;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,149:6:0 0,6,67:2:0 +X 2465 . T <*> 0 . DP=25;I16=14,10,0,0,857,32235,0,0,1347,78123,0,0,506,11994,0,0;QS=3,0;MQSB=0.679965;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,163:6:0 0,6,69:2:0 +X 2466 . G <*> 0 . DP=24;I16=14,9,0,0,852,32336,0,0,1318,77282,0,0,509,12025,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,157:6:0 0,6,63:2:0 +X 2467 . A <*> 0 . DP=24;I16=14,9,0,0,829,30725,0,0,1318,77282,0,0,513,12121,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,168:6:0 0,6,67:2:0 +X 2468 . G <*> 0 . DP=24;I16=15,9,0,0,890,34034,0,0,1347,78123,0,0,541,12807,0,0;QS=3,0;MQSB=0.72325;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,169:6:0 0,6,64:2:0 +X 2469 . G <*> 0 . DP=24;I16=15,9,0,0,865,32303,0,0,1347,78123,0,0,544,12882,0,0;QS=3,0;MQSB=0.72325;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,174:6:0 0,6,58:2:0 +X 2470 . G <*> 0 . DP=24;I16=14,9,0,0,829,30785,0,0,1318,77282,0,0,521,12295,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,178:6:0 0,6,58:2:0 +X 2471 . G <*> 0 . DP=24;I16=14,9,0,0,833,31429,0,0,1318,77282,0,0,523,12345,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,170:5:0 0,6,64:2:0 +X 2472 . G <*> 0 . DP=24;I16=13,9,0,0,774,28428,0,0,1289,76441,0,0,499,11733,0,0;QS=3,0;MQSB=0.955854;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,154:5:0 0,6,56:2:0 +X 2473 . A <*> 0 . DP=24;I16=13,9,0,0,775,28137,0,0,1258,73682,0,0,508,12078,0,0;QS=3,0;MQSB=0.834768;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,160:5:0 0,6,63:2:0 +X 2474 . A <*> 0 . DP=25;I16=15,9,0,0,851,31665,0,0,1378,80882,0,0,524,12322,0,0;QS=3,0;MQSB=0.865888;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,160:5:0 0,9,80:3:0 +X 2475 . G <*> 0 . DP=25;I16=15,9,0,0,913,35239,0,0,1378,80882,0,0,525,12323,0,0;QS=3,0;MQSB=0.865888;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,167:5:0 0,9,84:3:0 +X 2476 . G <*> 0 . DP=25;I16=13,9,0,0,776,28584,0,0,1289,76441,0,0,488,11544,0,0;QS=3,0;MQSB=0.955854;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,138:5:0 0,9,82:3:0 +X 2477 . A <*> 0 . DP=25;I16=14,9,0,0,867,34329,0,0,1318,77282,0,0,515,12223,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,178:5:0 0,9,91:3:0 +X 2478 . C <*> 0 . DP=25;I16=14,9,0,0,897,36911,0,0,1318,77282,0,0,517,12289,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,175:5:0 0,9,87:3:0 +X 2479 . T <*> 0 . DP=25;I16=15,9,0,0,921,37957,0,0,1378,80882,0,0,529,12467,0,0;QS=3,0;MQSB=0.865888;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,176:5:0 0,9,97:3:0 +X 2480 . G <*> 0 . DP=25;I16=14,9,0,0,877,35485,0,0,1349,80041,0,0,504,11864,0,0;QS=3,0;MQSB=0.960618;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,176:5:0 0,9,88:3:0 +X 2481 . C <*> 0 . DP=25;I16=13,9,0,0,848,34542,0,0,1289,76441,0,0,496,11838,0,0;QS=3,0;MQSB=0.955854;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,183:5:0 0,9,88:3:0 +X 2482 . T <*> 0 . DP=25;I16=15,9,0,0,905,37331,0,0,1378,80882,0,0,526,12430,0,0;QS=3,0;MQSB=0.865888;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,178:5:0 0,9,96:3:0 +X 2483 . T <*> 0 . DP=25;I16=14,9,0,0,879,36187,0,0,1318,77282,0,0,517,12311,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,180:5:0 0,9,89:3:0 +X 2484 . G <*> 0 . DP=25;I16=14,9,0,0,884,35142,0,0,1349,80041,0,0,494,11604,0,0;QS=3,0;MQSB=0.960618;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,174:5:0 0,9,84:3:0 +X 2485 . A T,<*> 0 . DP=25;I16=14,9,1,0,891,36757,17,289,1349,80041,29,841,490,11502,25,625;QS=2.96926,0.0307414,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.865888;BQB=1;MQ0F=0 PL:DP:DV 0,31,255,45,255,255:16:1 0,15,193,15,193,193:5:0 0,9,93,9,93,93:3:0 +X 2486 . G <*> 0 . DP=25;I16=15,9,0,0,898,36230,0,0,1378,80882,0,0,511,12041,0,0;QS=3,0;MQSB=0.865888;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,153:5:0 0,9,90:3:0 +X 2487 . C <*> 0 . DP=25;I16=14,9,0,0,793,30695,0,0,1349,80041,0,0,482,11346,0,0;QS=3,0;MQSB=0.960618;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,175:5:0 0,9,91:3:0 +X 2488 . C <*> 0 . DP=25;I16=13,9,0,0,841,34597,0,0,1289,76441,0,0,457,10841,0,0;QS=3,0;MQSB=0.955854;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,174:5:0 0,9,93:3:0 +X 2489 . C <*> 0 . DP=23;I16=11,9,0,0,801,34227,0,0,1169,69241,0,0,454,10788,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,187:5:0 0,9,93:3:0 +X 2490 . A <*> 0 . DP=23;I16=11,10,0,0,818,34642,0,0,1229,72841,0,0,451,10695,0,0;QS=3,0;MQSB=0.939898;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,175:5:0 0,12,128:4:0 +X 2491 . G <*> 0 . DP=23;I16=12,10,0,0,845,35143,0,0,1258,73682,0,0,471,11097,0,0;QS=3,0;MQSB=0.804615;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,178:5:0 0,12,121:4:0 +X 2492 . G A,<*> 0 . DP=23;I16=11,10,1,0,845,36207,16,256,1229,72841,29,841,446,10494,21,441;QS=2.96708,0.0329218,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.804615;BQB=1;MQ0F=0 PL:DP:DV 0,22,255,36,255,255:13:1 0,15,187,15,187,187:5:0 0,12,124,12,124,124:4:0 +X 2493 . A G,<*> 0 . DP=23;I16=11,10,1,0,855,37007,13,169,1229,72841,29,841,442,10340,20,400;QS=2.97269,0.0273109,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.804615;BQB=1;MQ0F=0 PL:DP:DV 0,25,255,36,255,255:13:1 0,15,191,15,191,191:5:0 0,12,127,12,127,127:4:0 +X 2494 . G <*> 0 . DP=23;I16=11,10,0,0,802,32720,0,0,1229,72841,0,0,437,10153,0,0;QS=3,0;MQSB=0.939898;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,179:5:0 0,12,118:4:0 +X 2495 . T <*> 0 . DP=23;I16=10,10,0,0,737,29861,0,0,1138,66482,0,0,413,9513,0,0;QS=3,0;MQSB=0.751477;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,172:5:0 0,12,113:4:0 +X 2496 . T <*> 0 . DP=23;I16=12,10,0,0,815,32793,0,0,1258,73682,0,0,442,10026,0,0;QS=3,0;MQSB=0.804615;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,183:5:0 0,12,123:4:0 +X 2497 . T <*> 0 . DP=22;I16=12,9,0,0,807,33723,0,0,1198,70082,0,0,436,9814,0,0;QS=3,0;MQSB=0.815018;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,177:5:0 0,12,131:4:0 +X 2498 . G <*> 0 . DP=22;I16=12,9,0,0,808,33264,0,0,1198,70082,0,0,430,9622,0,0;QS=3,0;MQSB=0.815018;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,173:5:0 0,12,127:4:0 +X 2499 . A <*> 0 . DP=22;I16=12,9,0,0,847,36803,0,0,1198,70082,0,0,424,9450,0,0;QS=3,0;MQSB=0.815018;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,185:5:0 0,12,133:4:0 +X 2500 . G <*> 0 . DP=22;I16=11,9,0,0,772,32546,0,0,1169,69241,0,0,404,9078,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,168:5:0 0,12,129:4:0 +X 2501 . G <*> 0 . DP=22;I16=11,8,0,0,768,33120,0,0,1109,65641,0,0,373,8293,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,146:4:0 0,12,118:4:0 +X 2502 . C <*> 0 . DP=22;I16=12,8,0,0,798,33902,0,0,1138,66482,0,0,378,8270,0,0;QS=3,0;MQSB=0.826565;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,155:4:0 0,12,125:4:0 +X 2503 . T <*> 0 . DP=22;I16=12,9,0,0,851,36841,0,0,1198,70082,0,0,396,8746,0,0;QS=3,0;MQSB=0.815018;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,180:5:0 0,12,139:4:0 +X 2504 . G <*> 0 . DP=22;I16=12,9,0,0,787,31955,0,0,1198,70082,0,0,389,8615,0,0;QS=3,0;MQSB=0.815018;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,171:5:0 0,12,129:4:0 +X 2505 . C <*> 0 . DP=21;I16=11,9,0,0,792,33440,0,0,1138,66482,0,0,383,8501,0,0;QS=3,0;MQSB=0.791547;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,169:5:0 0,12,132:4:0 +X 2506 . T <*> 0 . DP=22;I16=11,10,0,0,798,32868,0,0,1198,70082,0,0,376,8354,0,0;QS=3,0;MQSB=0.780412;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,175:5:0 0,15,169:5:0 +X 2507 . G <*> 0 . DP=21;I16=9,10,0,0,716,30074,0,0,1109,65641,0,0,365,8189,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,15,163:5:0 0,15,153:5:0 +X 2508 . T <*> 0 . DP=21;I16=9,10,0,0,724,30396,0,0,1109,65641,0,0,361,8089,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,15,158:5:0 0,15,162:5:0 +X 2509 . G T,<*> 0 . DP=21;I16=8,10,1,0,710,30408,35,1225,1049,62041,60,3600,330,7282,25,625;QS=2.80663,0.19337,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.920044;BQB=1;MQ0F=0 PL:DP:DV 0,27,253,27,253,253:9:0 20,0,122,32,125,150:5:1 0,15,163,15,163,163:5:0 +X 2510 . A <*> 0 . DP=21;I16=10,10,0,0,778,33128,0,0,1138,66482,0,0,352,7754,0,0;QS=3,0;MQSB=0.751477;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,174:5:0 0,15,161:5:0 +X 2511 . G <*> 0 . DP=21;I16=10,10,0,0,771,32165,0,0,1138,66482,0,0,344,7558,0,0;QS=3,0;MQSB=0.751477;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,161:5:0 0,15,159:5:0 +X 2512 . C <*> 0 . DP=21;I16=10,10,0,0,790,33406,0,0,1138,66482,0,0,336,7386,0,0;QS=3,0;MQSB=0.751477;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,175:5:0 0,15,160:5:0 +X 2513 . T <*> 0 . DP=21;I16=10,10,0,0,755,31503,0,0,1138,66482,0,0,327,7189,0,0;QS=3,0;MQSB=0.751477;MQ0F=0 PL:DP:DV 0,30,246:10:0 0,15,180:5:0 0,15,156:5:0 +X 2514 . G <*> 0 . DP=20;I16=9,10,0,0,702,28002,0,0,1109,65641,0,0,319,7017,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,15,171:5:0 0,15,155:5:0 +X 2515 . T <*> 0 . DP=19;I16=8,10,0,0,642,25888,0,0,1049,62041,0,0,312,6868,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,24,182:8:0 0,15,172:5:0 0,15,141:5:0 +X 2516 . G <*> 0 . DP=19;I16=8,10,0,0,685,28155,0,0,1049,62041,0,0,303,6641,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,24,211:8:0 0,15,175:5:0 0,15,147:5:0 +X 2517 . A <*> 0 . DP=18;I16=8,9,0,0,660,27600,0,0,989,58441,0,0,295,6435,0,0;QS=3,0;MQSB=0.91051;MQ0F=0 PL:DP:DV 0,24,215:8:0 0,12,139:4:0 0,15,161:5:0 +X 2518 . T <*> 0 . DP=17;I16=6,9,0,0,611,26911,0,0,900,54000,0,0,273,6023,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,188:7:0 0,12,144:4:0 0,12,146:4:0 +X 2519 . C <*> 0 . DP=16;I16=7,8,0,0,531,20111,0,0,900,54000,0,0,282,6078,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,175:7:0 0,12,141:4:0 0,12,125:4:0 +X 2520 . G <*> 0 . DP=15;I16=6,8,0,0,501,19731,0,0,840,50400,0,0,277,5923,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,187:7:0 0,12,129:4:0 0,9,101:3:0 +X 2521 . C <*> 0 . DP=15;I16=6,8,0,0,583,25777,0,0,840,50400,0,0,272,5782,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,214:7:0 0,12,149:4:0 0,9,111:3:0 +X 2522 . A <*> 0 . DP=16;I16=6,8,0,0,516,20930,0,0,840,50400,0,0,266,5606,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,173:7:0 0,12,139:4:0 0,9,114:3:0 +X 2523 . T <*> 0 . DP=16;I16=6,9,0,0,588,25538,0,0,900,54000,0,0,270,5546,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,207:7:0 0,15,157:5:0 0,9,117:3:0 +X 2524 . C <*> 0 . DP=16;I16=5,9,0,0,548,23502,0,0,840,50400,0,0,256,5342,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,182:6:0 0,15,156:5:0 0,9,112:3:0 +X 2525 . A C,<*> 0 . DP=17;I16=6,9,0,1,550,23138,28,784,900,54000,60,3600,248,5174,12,144;QS=2.86,0.14,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,24,168,24,168,168:8:0 13,0,138,25,141,159:5:1 0,9,117,9,117,117:3:0 +X 2526 . C <*> 0 . DP=18;I16=6,11,0,0,677,28649,0,0,1020,61200,0,0,256,5232,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,229:9:0 0,15,183:5:0 0,9,113:3:0 +X 2527 . T <*> 0 . DP=18;I16=6,11,0,0,674,29286,0,0,1020,61200,0,0,252,5118,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,217:9:0 0,15,183:5:0 0,9,119:3:0 +X 2528 . G <*> 0 . DP=18;I16=6,11,0,0,701,30729,0,0,1020,61200,0,0,248,5028,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,234:9:0 0,15,184:5:0 0,9,119:3:0 +X 2529 . C <*> 0 . DP=18;I16=6,11,0,0,676,28974,0,0,1020,61200,0,0,244,4962,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,15,175:5:0 0,9,117:3:0 +X 2530 . A <*> 0 . DP=18;I16=6,10,0,0,624,26620,0,0,960,57600,0,0,223,4631,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,209:9:0 0,12,153:4:0 0,9,116:3:0 +X 2531 . T <*> 0 . DP=17;I16=6,10,0,0,641,27911,0,0,960,57600,0,0,236,4852,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,210:8:0 0,15,175:5:0 0,9,122:3:0 +X 2532 . T <*> 0 . DP=17;I16=6,10,0,0,634,27460,0,0,960,57600,0,0,230,4708,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,212:8:0 0,15,173:5:0 0,9,117:3:0 +X 2533 . C <*> 0 . DP=18;I16=6,11,0,0,614,24196,0,0,1020,61200,0,0,224,4588,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,212:9:0 0,15,159:5:0 0,9,104:3:0 +X 2534 . C <*> 0 . DP=16;I16=5,10,0,0,595,25141,0,0,900,54000,0,0,221,4491,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,202:8:0 0,12,144:4:0 0,9,110:3:0 +X 2535 . A <*> 0 . DP=16;I16=5,10,0,0,617,27711,0,0,900,54000,0,0,218,4416,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,204:8:0 0,12,136:4:0 0,9,123:3:0 +X 2536 . G <*> 0 . DP=15;I16=4,10,0,0,543,23023,0,0,840,50400,0,0,216,4362,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,195:8:0 0,9,102:3:0 0,9,117:3:0 +X 2537 . C <*> 0 . DP=15;I16=4,10,0,0,555,24075,0,0,840,50400,0,0,213,4279,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,195:8:0 0,9,113:3:0 0,9,115:3:0 +X 2538 . C <*> 0 . DP=15;I16=5,9,0,0,510,21070,0,0,840,50400,0,0,211,4217,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,157:7:0 0,9,129:3:0 0,12,126:4:0 +X 2539 . C <*> 0 . DP=15;I16=5,9,0,0,464,16896,0,0,840,50400,0,0,209,4125,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,146:7:0 0,9,122:3:0 0,12,111:4:0 +X 2540 . G <*> 0 . DP=16;I16=6,9,0,0,548,21860,0,0,900,54000,0,0,207,4053,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,189:7:0 0,12,139:4:0 0,12,110:4:0 +X 2541 . G <*> 0 . DP=15;I16=5,9,0,0,535,22527,0,0,840,50400,0,0,207,4001,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,170:7:0 0,9,117:3:0 0,12,140:4:0 +X 2542 . T <*> 0 . DP=15;I16=4,9,0,0,527,23207,0,0,780,46800,0,0,203,3953,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,183:7:0 0,9,125:3:0 0,9,109:3:0 +X 2543 . G <*> 0 . DP=15;I16=5,9,0,0,540,23004,0,0,840,50400,0,0,207,3957,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,196:7:0 0,9,117:3:0 0,12,117:4:0 +X 2544 . A <*> 0 . DP=16;I16=6,9,0,0,569,24139,0,0,900,54000,0,0,207,3965,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,202:8:0 0,9,119:3:0 0,12,132:4:0 +X 2545 . C <*> 0 . DP=16;I16=6,9,0,0,583,24657,0,0,900,54000,0,0,208,3994,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,217:8:0 0,9,118:3:0 0,12,130:4:0 +X 2546 . A <*> 0 . DP=16;I16=6,9,0,0,608,27290,0,0,900,54000,0,0,209,4045,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,206:8:0 0,9,133:3:0 0,12,144:4:0 +X 2547 . G <*> 0 . DP=16;I16=6,9,0,0,597,26215,0,0,900,54000,0,0,211,4117,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,191:7:0 0,9,131:3:0 0,15,150:5:0 +X 2548 . A <*> 0 . DP=16;I16=6,9,0,0,632,28806,0,0,900,54000,0,0,214,4210,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,196:7:0 0,9,131:3:0 0,15,171:5:0 +X 2549 . G <*> 0 . DP=16;I16=6,9,0,0,594,25254,0,0,900,54000,0,0,217,4325,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,180:7:0 0,9,132:3:0 0,15,160:5:0 +X 2550 . T <*> 0 . DP=16;I16=6,9,0,0,572,24134,0,0,900,54000,0,0,219,4413,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,182:7:0 0,9,122:3:0 0,15,148:5:0 +X 2551 . G <*> 0 . DP=16;I16=6,9,0,0,578,24606,0,0,900,54000,0,0,220,4474,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,181:7:0 0,9,131:3:0 0,15,151:5:0 +X 2552 . A <*> 0 . DP=15;I16=6,8,0,0,585,26419,0,0,840,50400,0,0,221,4505,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,178:6:0 0,9,129:3:0 0,15,168:5:0 +X 2553 . G <*> 0 . DP=15;I16=6,8,0,0,528,21944,0,0,840,50400,0,0,222,4554,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,170:6:0 0,9,117:3:0 0,15,142:5:0 +X 2554 . T <*> 0 . DP=15;I16=6,8,0,0,543,23015,0,0,840,50400,0,0,223,4621,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,156:6:0 0,9,129:3:0 0,15,160:5:0 +X 2555 . C <*> 0 . DP=15;I16=6,8,0,0,566,24416,0,0,840,50400,0,0,224,4706,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,173:6:0 0,9,131:3:0 0,15,159:5:0 +X 2556 . A <*> 0 . DP=14;I16=6,7,0,0,487,20095,0,0,780,46800,0,0,226,4808,0,0;QS=3,0;MQSB=0.961166;MQ0F=0 PL:DP:DV 0,15,141:5:0 0,9,125:3:0 0,15,146:5:0 +X 2557 . C <*> 0 . DP=13;I16=5,8,0,0,471,17481,0,0,780,46800,0,0,249,5325,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,161:5:0 0,9,96:3:0 0,15,151:5:0 +X 2558 . T <*> 0 . DP=14;I16=5,9,0,0,535,20597,0,0,840,50400,0,0,251,5417,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,173:6:0 0,9,99:3:0 0,15,174:5:0 +X 2559 . G <*> 0 . DP=14;I16=5,9,0,0,509,18693,0,0,840,50400,0,0,253,5475,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,172:6:0 0,9,98:3:0 0,15,156:5:0 +X 2560 . T <*> 0 . DP=14;I16=5,9,0,0,489,17587,0,0,840,50400,0,0,255,5549,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,160:6:0 0,9,106:3:0 0,15,144:5:0 +X 2561 . C <*> 0 . DP=14;I16=5,9,0,0,489,17477,0,0,840,50400,0,0,257,5639,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,164:6:0 0,9,96:3:0 0,15,153:5:0 +X 2562 . T <*> 0 . DP=13;I16=5,8,0,0,460,17016,0,0,780,46800,0,0,260,5744,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,139:5:0 0,9,99:3:0 0,15,167:5:0 +X 2563 . C <*> 0 . DP=14;I16=5,8,0,0,433,15133,0,0,780,46800,0,0,263,5863,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,149:5:0 0,9,83:3:0 0,15,142:5:0 +X 2564 . A G,<*> 0 . DP=15;I16=1,4,4,5,174,6124,316,11352,300,18000,540,32400,61,1311,184,4034;QS=0.988263,2.01174,0;VDB=0.690812;SGB=-3.20711;RPB=0.197899;MQB=1;MQSB=1;BQB=0.965069;MQ0F=0 PL:DP:DV 88,0,78,98,87,171:6:3 57,0,56,63,62,117:4:2 124,12,0,124,12,124:4:4 +X 2565 . A <*> 0 . DP=15;I16=6,9,0,0,562,21216,0,0,900,54000,0,0,274,6076,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,178:6:0 0,12,134:4:0 0,15,166:5:0 +X 2566 . A <*> 0 . DP=15;I16=6,9,0,0,545,20019,0,0,900,54000,0,0,276,6098,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,181:6:0 0,12,120:4:0 0,15,162:5:0 +X 2567 . A <*> 0 . DP=16;I16=7,9,0,0,580,21342,0,0,960,57600,0,0,278,6136,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,177:6:0 0,15,151:5:0 0,15,166:5:0 +X 2568 . A <*> 0 . DP=16;I16=7,8,0,0,555,20795,0,0,900,54000,0,0,256,5566,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,180:6:0 0,12,132:4:0 0,15,167:5:0 +X 2569 . A <*> 0 . DP=17;I16=7,10,0,0,661,25943,0,0,1020,61200,0,0,284,6264,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,213:7:0 0,15,163:5:0 0,15,172:5:0 +X 2570 . G <*> 0 . DP=18;I16=8,10,0,0,664,24968,0,0,1080,64800,0,0,287,6305,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,213:7:0 0,15,152:5:0 0,18,176:6:0 +X 2571 . A <*> 0 . DP=18;I16=8,10,0,0,618,21870,0,0,1080,64800,0,0,291,6365,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,195:7:0 0,15,155:5:0 0,18,155:6:0 +X 2572 . A <*> 0 . DP=18;I16=8,10,0,0,631,22829,0,0,1080,64800,0,0,295,6445,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,194:7:0 0,15,150:5:0 0,18,173:6:0 +X 2573 . A <*> 0 . DP=18;I16=8,10,0,0,690,26830,0,0,1080,64800,0,0,298,6494,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,210:7:0 0,15,170:5:0 0,18,183:6:0 +X 2574 . G <*> 0 . DP=18;I16=8,10,0,0,664,24884,0,0,1080,64800,0,0,301,6561,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,211:7:0 0,15,152:5:0 0,18,176:6:0 +X 2575 . G <*> 0 . DP=18;I16=8,10,0,0,642,23904,0,0,1080,64800,0,0,305,6645,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,242:8:0 0,15,145:5:0 0,15,140:5:0 +X 2576 . A <*> 0 . DP=18;I16=7,10,0,0,595,21311,0,0,1020,61200,0,0,285,6121,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,210:8:0 0,15,153:5:0 0,12,131:4:0 +X 2577 . A <*> 0 . DP=19;I16=8,10,0,0,682,26398,0,0,1080,64800,0,0,290,6240,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,244:8:0 0,15,161:5:0 0,15,155:5:0 +X 2578 . G <*> 0 . DP=18;I16=9,9,0,0,643,24115,0,0,1080,64800,0,0,322,7002,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,249:8:0 0,12,114:4:0 0,18,161:6:0 +X 2579 . A <*> 0 . DP=18;I16=9,8,0,0,634,23870,0,0,1020,61200,0,0,304,6532,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,229:8:0 0,9,110:3:0 0,18,176:6:0 +X 2580 . A <*> 0 . DP=18;I16=9,9,0,0,629,22593,0,0,1080,64800,0,0,336,7330,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,223:8:0 0,12,117:4:0 0,18,169:6:0 +X 2581 . A <*> 0 . DP=19;I16=10,9,0,0,691,25669,0,0,1140,68400,0,0,343,7521,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,12,133:4:0 0,18,166:6:0 +X 2582 . T <*> 0 . DP=19;I16=10,9,0,0,674,24218,0,0,1140,68400,0,0,350,7682,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,235:9:0 0,12,138:4:0 0,18,168:6:0 +X 2583 . A <*> 0 . DP=19;I16=10,9,0,0,693,25465,0,0,1140,68400,0,0,357,7865,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,247:9:0 0,12,126:4:0 0,18,178:6:0 +X 2584 . A <*> 0 . DP=19;I16=10,9,0,0,702,26340,0,0,1140,68400,0,0,363,8019,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,243:9:0 0,12,134:4:0 0,18,187:6:0 +X 2585 . A <*> 0 . DP=19;I16=9,9,0,0,690,26700,0,0,1080,64800,0,0,350,7818,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,250:9:0 0,9,114:3:0 0,18,190:6:0 +X 2586 . G <*> 0 . DP=19;I16=10,9,0,0,714,27314,0,0,1140,68400,0,0,373,8283,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,12,127:4:0 0,18,176:6:0 +X 2587 . A <*> 0 . DP=20;I16=9,9,0,0,665,24781,0,0,1049,62041,0,0,343,7717,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,137:4:0 0,12,136:4:0 +X 2588 . A <*> 0 . DP=21;I16=12,9,0,0,737,26531,0,0,1229,72841,0,0,384,8620,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,138:4:0 0,18,162:6:0 +X 2589 . A <*> 0 . DP=22;I16=13,9,0,0,780,28412,0,0,1289,76441,0,0,390,8770,0,0;QS=3,0;MQSB=0.955854;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,142:4:0 0,18,170:6:0 +X 2590 . A <*> 0 . DP=22;I16=13,9,0,0,774,28352,0,0,1289,76441,0,0,396,8894,0,0;QS=3,0;MQSB=0.955854;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,135:4:0 0,18,160:6:0 +X 2591 . C <*> 0 . DP=21;I16=13,8,0,0,765,28617,0,0,1229,72841,0,0,403,9041,0,0;QS=3,0;MQSB=0.95891;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,136:4:0 0,15,136:5:0 +X 2592 . A <*> 0 . DP=21;I16=13,8,0,0,763,28325,0,0,1229,72841,0,0,410,9210,0,0;QS=3,0;MQSB=0.95891;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,140:4:0 0,15,139:5:0 +X 2593 . A <*> 0 . DP=21;I16=13,8,0,0,754,27888,0,0,1229,72841,0,0,416,9350,0,0;QS=3,0;MQSB=0.95891;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,141:4:0 0,15,147:5:0 +X 2594 . A <*> 0 . DP=21;I16=13,8,0,0,775,29179,0,0,1229,72841,0,0,422,9510,0,0;QS=3,0;MQSB=0.95891;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,130:4:0 0,15,153:5:0 +X 2595 . T <*> 0 . DP=22;I16=14,8,0,0,766,27472,0,0,1289,76441,0,0,427,9639,0,0;QS=3,0;MQSB=0.963419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,119:4:0 0,15,143:5:0 +X 2596 . A <*> 0 . DP=22;I16=13,8,0,0,751,27409,0,0,1229,72841,0,0,407,9111,0,0;QS=3,0;MQSB=0.95891;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,123:4:0 0,12,129:4:0 +X 2597 . A <*> 0 . DP=22;I16=14,8,0,0,811,30147,0,0,1289,76441,0,0,437,9851,0,0;QS=3,0;MQSB=0.963419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,145:4:0 0,15,145:5:0 +X 2598 . A <*> 0 . DP=22;I16=14,8,0,0,817,30915,0,0,1289,76441,0,0,442,9984,0,0;QS=3,0;MQSB=0.963419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,136:4:0 0,15,159:5:0 +X 2599 . A <*> 0 . DP=22;I16=14,8,0,0,800,29912,0,0,1289,76441,0,0,447,10135,0,0;QS=3,0;MQSB=0.963419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,126:4:0 0,15,150:5:0 +X 2600 . A <*> 0 . DP=22;I16=14,8,0,0,784,29138,0,0,1289,76441,0,0,451,10255,0,0;QS=3,0;MQSB=0.963419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,113:4:0 0,15,150:5:0 +X 2601 . T <*> 0 . DP=22;I16=14,8,0,0,770,27820,0,0,1289,76441,0,0,454,10344,0,0;QS=3,0;MQSB=0.963419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,118:4:0 0,15,142:5:0 +X 2602 . A <*> 0 . DP=23;I16=15,8,0,0,825,29971,0,0,1349,80041,0,0,457,10451,0,0;QS=3,0;MQSB=0.967216;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,143:4:0 0,18,154:6:0 +X 2603 . A <*> 0 . DP=23;I16=15,8,0,0,862,32840,0,0,1349,80041,0,0,460,10526,0,0;QS=3,0;MQSB=0.967216;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,138:4:0 0,18,172:6:0 +X 2604 . T <*> 0 . DP=23;I16=15,8,0,0,822,29902,0,0,1349,80041,0,0,463,10619,0,0;QS=3,0;MQSB=0.967216;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,129:4:0 0,18,154:6:0 +X 2605 . A <*> 0 . DP=23;I16=14,8,0,0,845,32617,0,0,1289,76441,0,0,441,10105,0,0;QS=3,0;MQSB=0.963419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,143:4:0 0,15,157:5:0 +X 2606 . G <*> 0 . DP=23;I16=14,8,0,0,812,30796,0,0,1289,76441,0,0,444,10234,0,0;QS=3,0;MQSB=0.963419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,129:4:0 0,15,142:5:0 +X 2607 . T <*> 0 . DP=22;I16=15,7,0,0,782,28440,0,0,1289,76441,0,0,472,10954,0,0;QS=3,0;MQSB=0.970024;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,119:4:0 0,15,132:5:0 +X 2608 . G <*> 0 . DP=22;I16=15,7,0,0,851,33169,0,0,1289,76441,0,0,474,11014,0,0;QS=3,0;MQSB=0.970024;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,132:4:0 0,15,127:5:0 +X 2609 . C <*> 0 . DP=22;I16=15,7,0,0,796,29454,0,0,1289,76441,0,0,475,11041,0,0;QS=3,0;MQSB=0.970024;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,137:4:0 0,15,124:5:0 +X 2610 . A <*> 0 . DP=22;I16=15,7,0,0,830,31684,0,0,1289,76441,0,0,476,11086,0,0;QS=3,0;MQSB=0.970024;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,146:4:0 0,15,121:5:0 +X 2611 . G <*> 0 . DP=22;I16=15,7,0,0,824,32048,0,0,1289,76441,0,0,477,11149,0,0;QS=3,0;MQSB=0.970024;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,129:4:0 0,15,122:5:0 +X 2612 . A <*> 0 . DP=22;I16=14,7,0,0,771,29035,0,0,1229,72841,0,0,453,10605,0,0;QS=3,0;MQSB=0.966484;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,130:4:0 0,12,117:4:0 +X 2613 . C <*> 0 . DP=22;I16=15,7,0,0,832,31926,0,0,1289,76441,0,0,478,11278,0,0;QS=3,0;MQSB=0.970024;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,138:4:0 0,15,120:5:0 +X 2614 . A <*> 0 . DP=21;I16=15,6,0,0,791,30065,0,0,1229,72841,0,0,477,11241,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,110:3:0 0,15,140:5:0 +X 2615 . A <*> 0 . DP=21;I16=15,6,0,0,777,29101,0,0,1229,72841,0,0,475,11167,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,99:3:0 0,15,142:5:0 +X 2616 . A <*> 0 . DP=21;I16=15,6,0,0,734,26922,0,0,1229,72841,0,0,472,11056,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,90:3:0 0,15,144:5:0 +X 2617 . A <*> 0 . DP=21;I16=15,6,0,0,810,31654,0,0,1229,72841,0,0,469,10959,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,95:3:0 0,15,140:5:0 +X 2618 . G <*> 0 . DP=23;I16=16,6,0,0,863,34219,0,0,1289,76441,0,0,441,10251,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,74:2:0 0,15,132:5:0 +X 2619 . G <*> 0 . DP=23;I16=16,6,0,0,807,30109,0,0,1289,76441,0,0,439,10135,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,66:2:0 0,15,127:5:0 +X 2620 . C <*> 0 . DP=23;I16=16,7,0,0,780,28242,0,0,1349,80041,0,0,462,10664,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,87:3:0 0,15,115:5:0 +X 2621 . C <*> 0 . DP=23;I16=16,7,0,0,860,32944,0,0,1349,80041,0,0,459,10537,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,112:3:0 0,15,124:5:0 +X 2622 . T <*> 0 . DP=24;I16=17,7,0,0,908,35474,0,0,1409,83641,0,0,456,10428,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,115:3:0 0,15,134:5:0 +X 2623 . T <*> 0 . DP=24;I16=17,7,0,0,850,30978,0,0,1409,83641,0,0,453,10289,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,114:3:0 0,15,129:5:0 +X 2624 . G <*> 0 . DP=24;I16=17,7,0,0,882,33332,0,0,1409,83641,0,0,450,10172,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,101:3:0 0,15,133:5:0 +X 2625 . A <*> 0 . DP=23;I16=17,6,0,0,855,32593,0,0,1349,80041,0,0,448,10076,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,114:3:0 0,15,135:5:0 +X 2626 . C <*> 0 . DP=23;I16=17,6,0,0,847,31625,0,0,1349,80041,0,0,446,10000,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,100:3:0 0,15,122:5:0 +X 2627 . C <*> 0 . DP=23;I16=17,6,0,0,863,32865,0,0,1349,80041,0,0,444,9944,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,104:3:0 0,15,129:5:0 +X 2628 . C <*> 0 . DP=24;I16=17,6,0,0,793,28559,0,0,1349,80041,0,0,431,9757,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,95:3:0 0,15,127:5:0 +X 2629 . A <*> 0 . DP=24;I16=18,6,0,0,893,33537,0,0,1409,83641,0,0,439,9789,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,101:3:0 0,18,148:6:0 +X 2630 . T <*> 0 . DP=24;I16=17,6,0,0,836,31094,0,0,1380,82800,0,0,412,9116,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,112:3:0 0,18,140:6:0 +X 2631 . C <*> 0 . DP=24;I16=18,6,0,0,900,34378,0,0,1409,83641,0,0,435,9713,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,104:3:0 0,18,142:6:0 +X 2632 . T <*> 0 . DP=24;I16=18,6,0,0,937,37097,0,0,1409,83641,0,0,433,9705,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,113:3:0 0,18,164:6:0 +X 2633 . A <*> 0 . DP=23;I16=18,5,0,0,801,28913,0,0,1349,80041,0,0,431,9667,0,0;QS=3,0;MQSB=0.982789;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,95:3:0 0,18,148:6:0 +X 2634 . G <*> 0 . DP=23;I16=19,3,0,0,861,34125,0,0,1289,76441,0,0,405,9023,0,0;QS=3,0;MQSB=0.989755;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,74:2:0 0,18,149:6:0 +X 2635 . C <*> 0 . DP=23;I16=19,4,0,0,848,32154,0,0,1349,80041,0,0,429,9599,0,0;QS=3,0;MQSB=0.986928;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,107:3:0 0,18,148:6:0 +X 2636 . T <*> 0 . DP=24;I16=19,4,0,0,871,33973,0,0,1349,80041,0,0,428,9572,0,0;QS=3,0;MQSB=0.986928;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,98:3:0 0,18,160:6:0 +X 2637 . T <*> 0 . DP=24;I16=19,5,0,0,871,32073,0,0,1409,83641,0,0,428,9568,0,0;QS=3,0;MQSB=0.984335;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,111:3:0 0,18,144:6:0 +X 2638 . T <*> 0 . DP=24;I16=19,5,0,0,821,28851,0,0,1409,83641,0,0,428,9588,0,0;QS=3,0;MQSB=0.984335;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,103:3:0 0,18,135:6:0 +X 2639 . G <*> 0 . DP=24;I16=18,6,0,0,842,30840,0,0,1409,83641,0,0,428,9582,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,106:3:0 0,15,125:5:0 +X 2640 . G <*> 0 . DP=24;I16=17,6,0,0,749,25957,0,0,1380,82800,0,0,404,8976,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,84:3:0 0,15,117:5:0 +X 2641 . C <*> 0 . DP=23;I16=17,6,0,0,834,31792,0,0,1349,80041,0,0,431,9645,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,61:2:0 0,15,129:5:0 +X 2642 . C <*> 0 . DP=23;I16=17,6,0,0,809,30033,0,0,1349,80041,0,0,433,9713,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,58:2:0 0,15,131:5:0 +X 2643 . C <*> 0 . DP=23;I16=17,6,0,0,856,33004,0,0,1349,80041,0,0,434,9756,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,57:2:0 0,15,133:5:0 +X 2644 . T <*> 0 . DP=22;I16=16,5,0,0,805,31419,0,0,1229,72841,0,0,428,9648,0,0;QS=3,0;MQSB=0.978919;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,73:2:0 0,15,143:5:0 +X 2645 . C <*> 0 . DP=22;I16=15,6,0,0,823,32499,0,0,1229,72841,0,0,415,9323,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,78:2:0 0,12,122:4:0 +X 2646 . A <*> 0 . DP=22;I16=16,6,0,0,826,31566,0,0,1289,76441,0,0,430,9524,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,79:2:0 0,15,129:5:0 +X 2647 . G <*> 0 . DP=22;I16=16,6,0,0,803,30643,0,0,1289,76441,0,0,428,9460,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,77:2:0 0,15,129:5:0 +X 2648 . C <*> 0 . DP=21;I16=15,6,0,0,811,31709,0,0,1229,72841,0,0,426,9368,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,80:2:0 0,12,118:4:0 +X 2649 . A <*> 0 . DP=23;I16=16,6,0,0,789,29215,0,0,1258,73682,0,0,414,9196,0,0;QS=3,0;MQSB=0.934321;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,93:3:0 0,12,105:4:0 +X 2650 . T <*> 0 . DP=23;I16=16,7,0,0,856,32340,0,0,1318,77282,0,0,423,9197,0,0;QS=3,0;MQSB=0.955805;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,103:3:0 0,12,118:4:0 +X 2651 . C <*> 0 . DP=23;I16=16,7,0,0,871,33599,0,0,1318,77282,0,0,422,9124,0,0;QS=3,0;MQSB=0.955805;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,95:3:0 0,12,121:4:0 +X 2652 . A <*> 0 . DP=23;I16=16,7,0,0,820,30324,0,0,1318,77282,0,0,421,9077,0,0;QS=3,0;MQSB=0.955805;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,87:3:0 0,12,126:4:0 +X 2653 . A <*> 0 . DP=23;I16=15,6,0,0,759,28489,0,0,1198,70082,0,0,389,8395,0,0;QS=3,0;MQSB=0.940481;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,73:2:0 0,9,109:3:0 +X 2654 . C <*> 0 . DP=23;I16=16,7,0,0,836,31006,0,0,1318,77282,0,0,393,8385,0,0;QS=3,0;MQSB=0.955805;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,88:3:0 0,9,99:3:0 +X 2655 . C <*> 0 . DP=23;I16=16,7,0,0,774,27190,0,0,1318,77282,0,0,392,8364,0,0;QS=3,0;MQSB=0.955805;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,83:3:0 0,9,95:3:0 +X 2656 . G <*> 0 . DP=24;I16=17,7,0,0,781,25689,0,0,1378,80882,0,0,390,8320,0,0;QS=3,0;MQSB=0.95083;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,116:4:0 0,9,74:3:0 +X 2657 . C <*> 0 . DP=24;I16=17,6,0,0,871,33435,0,0,1349,80041,0,0,381,8241,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,98:3:0 0,9,99:3:0 +X 2658 . T <*> 0 . DP=23;I16=17,6,0,0,897,35255,0,0,1318,77282,0,0,389,8319,0,0;QS=3,0;MQSB=0.92854;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,133:4:0 0,9,107:3:0 +X 2659 . A <*> 0 . DP=23;I16=17,6,0,0,817,29729,0,0,1318,77282,0,0,389,8361,0,0;QS=3,0;MQSB=0.92854;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,120:4:0 0,9,93:3:0 +X 2660 . G <*> 0 . DP=23;I16=17,6,0,0,900,35462,0,0,1318,77282,0,0,389,8379,0,0;QS=3,0;MQSB=0.92854;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,126:4:0 0,9,94:3:0 +X 2661 . A <*> 0 . DP=24;I16=18,6,0,0,871,32185,0,0,1378,80882,0,0,390,8422,0,0;QS=3,0;MQSB=0.923116;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,127:4:0 0,9,104:3:0 +X 2662 . T <*> 0 . DP=24;I16=17,6,0,0,836,30812,0,0,1349,80041,0,0,366,7816,0,0;QS=3,0;MQSB=0.83771;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,122:4:0 0,9,99:3:0 +X 2663 . A <*> 0 . DP=24;I16=17,6,0,0,827,30583,0,0,1318,77282,0,0,389,8341,0,0;QS=3,0;MQSB=0.92854;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,104:4:0 0,9,101:3:0 +X 2664 . C <*> 0 . DP=23;I16=17,6,0,0,787,28083,0,0,1318,77282,0,0,388,8270,0,0;QS=3,0;MQSB=0.92854;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,107:4:0 0,9,91:3:0 +X 2665 . G <*> 0 . DP=23;I16=17,6,0,0,728,23290,0,0,1318,77282,0,0,386,8178,0,0;QS=3,0;MQSB=0.92854;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,112:4:0 0,9,78:3:0 +X 2666 . T <*> 0 . DP=23;I16=17,5,0,0,799,29273,0,0,1289,76441,0,0,367,7825,0,0;QS=3,0;MQSB=0.981001;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,105:3:0 0,9,94:3:0 +X 2667 . C <*> 0 . DP=23;I16=16,5,0,0,792,30190,0,0,1260,75600,0,0,345,7393,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,96:3:0 0,9,98:3:0 +X 2668 . C <*> 0 . DP=24;I16=18,6,0,0,832,29692,0,0,1378,80882,0,0,381,8069,0,0;QS=3,0;MQSB=0.923116;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,107:4:0 0,9,95:3:0 +X 2669 . C <*> 0 . DP=23;I16=18,5,0,0,829,30953,0,0,1318,77282,0,0,383,8087,0,0;QS=3,0;MQSB=0.889264;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,120:4:0 0,9,88:3:0 +X 2670 . T <*> 0 . DP=23;I16=17,5,0,0,841,32669,0,0,1289,76441,0,0,368,7828,0,0;QS=3,0;MQSB=0.801124;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,131:4:0 0,9,100:3:0 +X 2671 . C <*> 0 . DP=22;I16=17,5,0,0,842,32448,0,0,1258,73682,0,0,386,8110,0,0;QS=3,0;MQSB=0.895399;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,128:4:0 0,6,70:2:0 +X 2672 . C <*> 0 . DP=22;I16=17,5,0,0,808,30180,0,0,1258,73682,0,0,388,8164,0,0;QS=3,0;MQSB=0.895399;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,129:4:0 0,6,75:2:0 +X 2673 . C <*> 0 . DP=22;I16=17,5,0,0,842,32528,0,0,1258,73682,0,0,390,8246,0,0;QS=3,0;MQSB=0.895399;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,133:4:0 0,6,75:2:0 +X 2674 . T <*> 0 . DP=23;I16=17,6,0,0,860,33242,0,0,1318,77282,0,0,392,8356,0,0;QS=3,0;MQSB=0.92854;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,142:4:0 0,6,79:2:0 +X 2675 . T <*> 0 . DP=22;I16=16,6,0,0,756,26986,0,0,1258,73682,0,0,394,8392,0,0;QS=3,0;MQSB=0.934321;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,134:4:0 0,6,74:2:0 +X 2676 . T <*> 0 . DP=22;I16=16,6,0,0,774,28022,0,0,1258,73682,0,0,396,8452,0,0;QS=3,0;MQSB=0.934321;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,135:4:0 0,6,75:2:0 +X 2677 . C <*> 0 . DP=22;I16=16,6,0,0,866,34444,0,0,1258,73682,0,0,398,8536,0,0;QS=3,0;MQSB=0.934321;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,131:4:0 0,6,77:2:0 +X 2678 . T <*> 0 . DP=22;I16=16,5,0,0,818,32216,0,0,1229,72841,0,0,374,7970,0,0;QS=3,0;MQSB=0.978919;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,111:3:0 0,6,80:2:0 +X 2679 . T <*> 0 . DP=22;I16=16,6,0,0,808,29912,0,0,1258,73682,0,0,400,8680,0,0;QS=3,0;MQSB=0.934321;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,137:4:0 0,6,75:2:0 +X 2680 . C <*> 0 . DP=23;I16=16,7,0,0,873,33605,0,0,1318,77282,0,0,400,8740,0,0;QS=3,0;MQSB=0.955805;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,131:4:0 0,6,70:2:0 +X 2681 . T <*> 0 . DP=22;I16=15,7,0,0,820,31248,0,0,1258,73682,0,0,402,8824,0,0;QS=3,0;MQSB=0.961028;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,133:4:0 0,6,75:2:0 +X 2682 . G <*> 0 . DP=22;I16=15,7,0,0,831,31865,0,0,1258,73682,0,0,403,8881,0,0;QS=3,0;MQSB=0.961028;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,135:4:0 0,6,64:2:0 +X 2683 . G <*> 0 . DP=22;I16=13,6,0,0,702,26368,0,0,1109,65641,0,0,394,8926,0,0;QS=3,0;MQSB=0.850016;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,136:4:0 0,6,53:2:0 +X 2684 . G <*> 0 . DP=22;I16=14,7,0,0,754,27678,0,0,1229,72841,0,0,403,9057,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,128:4:0 0,6,62:2:0 +X 2685 . G <*> 0 . DP=22;I16=15,7,0,0,736,25916,0,0,1258,73682,0,0,406,9184,0,0;QS=3,0;MQSB=0.961028;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,130:4:0 0,6,45:2:0 +X 2686 . C <*> 0 . DP=22;I16=15,7,0,0,803,29933,0,0,1258,73682,0,0,406,9278,0,0;QS=3,0;MQSB=0.961028;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,134:4:0 0,6,68:2:0 +X 2687 . A <*> 0 . DP=21;I16=13,7,0,0,716,26356,0,0,1169,69241,0,0,406,9340,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,136:4:0 0,6,61:2:0 +X 2688 . C <*> 0 . DP=20;I16=13,7,0,0,750,28308,0,0,1169,69241,0,0,407,9417,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,134:4:0 0,6,66:2:0 +X 2689 . A <*> 0 . DP=19;I16=12,7,0,0,741,29105,0,0,1109,65641,0,0,409,9507,0,0;QS=3,0;MQSB=0.879351;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,140:4:0 0,6,73:2:0 +X 2690 . G <*> 0 . DP=20;I16=12,8,0,0,751,28929,0,0,1169,69241,0,0,411,9609,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,135:4:0 0,6,61:2:0 +X 2691 . G <*> 0 . DP=20;I16=12,7,0,0,682,25006,0,0,1109,65641,0,0,403,9603,0,0;QS=3,0;MQSB=0.879351;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,132:4:0 0,6,63:2:0 +X 2692 . T <*> 0 . DP=20;I16=12,8,0,0,648,21758,0,0,1169,69241,0,0,417,9853,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,125:4:0 0,6,72:2:0 +X 2693 . C <*> 0 . DP=20;I16=12,8,0,0,779,30645,0,0,1169,69241,0,0,418,9898,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,130:4:0 0,6,70:2:0 +X 2694 . A <*> 0 . DP=21;I16=13,8,0,0,723,25649,0,0,1229,72841,0,0,417,9859,0,0;QS=3,0;MQSB=0.895122;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,126:4:0 0,6,73:2:0 +X 2695 . C <*> 0 . DP=20;I16=12,8,0,0,757,28835,0,0,1169,69241,0,0,418,9834,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,130:4:0 0,6,63:2:0 +X 2696 . A <*> 0 . DP=20;I16=12,8,0,0,733,27357,0,0,1169,69241,0,0,419,9823,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,130:4:0 0,6,69:2:0 +X 2697 . C <*> 0 . DP=20;I16=12,8,0,0,738,27604,0,0,1169,69241,0,0,419,9777,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,128:4:0 0,6,66:2:0 +X 2698 . T <*> 0 . DP=21;I16=12,8,0,0,788,31268,0,0,1169,69241,0,0,419,9747,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,144:4:0 0,6,77:2:0 +X 2699 . C <*> 0 . DP=22;I16=13,9,0,0,864,34148,0,0,1258,73682,0,0,443,10309,0,0;QS=3,0;MQSB=0.686045;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,135:4:0 0,9,98:3:0 +X 2700 . T <*> 0 . DP=22;I16=13,9,0,0,850,33296,0,0,1258,73682,0,0,444,10310,0,0;QS=3,0;MQSB=0.686045;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,141:4:0 0,9,105:3:0 +X 2701 . C <*> 0 . DP=22;I16=13,9,0,0,863,34157,0,0,1258,73682,0,0,444,10278,0,0;QS=3,0;MQSB=0.686045;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,140:4:0 0,9,94:3:0 +X 2702 . T <*> 0 . DP=22;I16=13,9,0,0,837,32525,0,0,1258,73682,0,0,444,10262,0,0;QS=3,0;MQSB=0.686045;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,143:4:0 0,9,83:3:0 +X 2703 . T <*> 0 . DP=21;I16=12,8,0,0,717,25881,0,0,1169,69241,0,0,420,9636,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,130:4:0 0,3,32:1:0 +X 2704 . C <*> 0 . DP=21;I16=12,9,0,0,794,30766,0,0,1198,70082,0,0,445,10225,0,0;QS=3,0;MQSB=0.695144;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,137:4:0 0,6,55:2:0 +X 2705 . C <*> 0 . DP=21;I16=12,9,0,0,809,31649,0,0,1198,70082,0,0,445,10205,0,0;QS=3,0;MQSB=0.695144;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,136:4:0 0,6,56:2:0 +X 2706 . A <*> 0 . DP=22;I16=12,10,0,0,820,31386,0,0,1258,73682,0,0,444,10150,0,0;QS=3,0;MQSB=0.731218;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,141:4:0 0,6,70:2:0 +X 2707 . G <*> 0 . DP=22;I16=12,10,0,0,832,32104,0,0,1258,73682,0,0,444,10110,0,0;QS=3,0;MQSB=0.731218;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,139:4:0 0,6,60:2:0 +X 2708 . G <*> 0 . DP=22;I16=12,10,0,0,777,28329,0,0,1258,73682,0,0,444,10086,0,0;QS=3,0;MQSB=0.731218;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,136:4:0 0,6,57:2:0 +X 2709 . T <*> 0 . DP=22;I16=12,9,0,0,761,28341,0,0,1229,72841,0,0,418,9404,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,137:4:0 0,3,39:1:0 +X 2710 . C <*> 0 . DP=23;I16=12,10,0,0,840,32478,0,0,1289,76441,0,0,417,9365,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,134:4:0 0,3,38:1:0 +X 2711 . T <*> 0 . DP=24;I16=13,11,0,0,893,33721,0,0,1378,80882,0,0,442,9970,0,0;QS=3,0;MQSB=0.75304;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,138:4:0 0,6,72:2:0 +X 2712 . A <*> 0 . DP=24;I16=13,11,0,0,889,33333,0,0,1378,80882,0,0,443,9971,0,0;QS=3,0;MQSB=0.75304;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,141:4:0 0,6,65:2:0 +X 2713 . G T,<*> 0 . DP=25;I16=13,11,0,1,915,35485,14,196,1378,80882,29,841,419,9369,25,625;QS=2.72549,0.27451,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.569783;BQB=1;MQ0F=0 PL:DP:DV 0,57,255,57,255,255:19:0 0,12,131,12,131,131:4:0 8,0,31,11,34,42:2:1 +X 2714 . G <*> 0 . DP=25;I16=13,11,0,0,891,33457,0,0,1378,80882,0,0,444,9990,0,0;QS=3,0;MQSB=0.75304;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,132:4:0 0,6,64:2:0 +X 2715 . A <*> 0 . DP=25;I16=13,12,0,0,888,32012,0,0,1407,81723,0,0,446,10014,0,0;QS=3,0;MQSB=0.569783;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,12,135:4:0 0,6,63:2:0 +X 2716 . T <*> 0 . DP=26;I16=13,13,0,0,937,34241,0,0,1467,85323,0,0,446,10012,0,0;QS=3,0;MQSB=0.606531;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,12,134:4:0 0,9,90:3:0 +X 2717 . G <*> 0 . DP=26;I16=13,12,0,0,939,35995,0,0,1438,84482,0,0,422,9410,0,0;QS=3,0;MQSB=0.778801;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,12,134:4:0 0,6,72:2:0 +X 2718 . C <*> 0 . DP=24;I16=12,11,0,0,864,33118,0,0,1318,77282,0,0,425,9457,0,0;QS=3,0;MQSB=0.7613;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,130:4:0 0,6,65:2:0 +X 2719 . A <*> 0 . DP=24;I16=12,12,0,0,911,35371,0,0,1347,78123,0,0,452,10102,0,0;QS=3,0;MQSB=0.582748;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,139:4:0 0,9,99:3:0 +X 2720 . G <*> 0 . DP=24;I16=12,12,0,0,940,37044,0,0,1347,78123,0,0,453,10095,0,0;QS=3,0;MQSB=0.582748;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,136:4:0 0,9,97:3:0 +X 2721 . C <*> 0 . DP=24;I16=12,11,0,0,881,34499,0,0,1318,77282,0,0,429,9485,0,0;QS=3,0;MQSB=0.7613;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,131:4:0 0,6,76:2:0 +X 2722 . T <*> 0 . DP=24;I16=11,13,0,0,898,34310,0,0,1347,78123,0,0,456,10146,0,0;QS=3,0;MQSB=0.633229;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,156:5:0 0,9,98:3:0 +X 2723 . G <*> 0 . DP=25;I16=12,13,0,0,941,36257,0,0,1407,81723,0,0,459,10203,0,0;QS=3,0;MQSB=0.619223;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,184:6:0 0,9,76:3:0 +X 2724 . A <*> 0 . DP=25;I16=12,13,0,0,917,34211,0,0,1407,81723,0,0,462,10234,0,0;QS=3,0;MQSB=0.619223;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,188:6:0 0,9,84:3:0 +X 2725 . G <*> 0 . DP=25;I16=12,12,0,0,916,35656,0,0,1378,80882,0,0,438,9566,0,0;QS=3,0;MQSB=0.786628;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,185:6:0 0,6,67:2:0 +X 2726 . G <*> 0 . DP=25;I16=11,12,0,0,841,31809,0,0,1287,74523,0,0,437,9545,0,0;QS=3,0;MQSB=0.597127;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,186:6:0 0,6,46:2:0 +X 2727 . G <*> 0 . DP=25;I16=12,13,0,0,889,32233,0,0,1407,81723,0,0,464,10182,0,0;QS=3,0;MQSB=0.619223;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,194:7:0 0,6,56:2:0 +X 2728 . G <*> 0 . DP=25;I16=12,13,0,0,883,32287,0,0,1407,81723,0,0,467,10219,0,0;QS=3,0;MQSB=0.619223;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,189:7:0 0,6,50:2:0 +X 2729 . T <*> 0 . DP=25;I16=12,13,0,0,871,31019,0,0,1407,81723,0,0,469,10233,0,0;QS=3,0;MQSB=0.619223;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,189:7:0 0,6,62:2:0 +X 2730 . G <*> 0 . DP=25;I16=12,13,0,0,907,34299,0,0,1407,81723,0,0,471,10275,0,0;QS=3,0;MQSB=0.619223;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,192:7:0 0,6,49:2:0 +X 2731 . C <*> 0 . DP=25;I16=12,13,0,0,893,33027,0,0,1407,81723,0,0,473,10345,0,0;QS=3,0;MQSB=0.619223;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,192:7:0 0,6,52:2:0 +X 2732 . C <*> 0 . DP=25;I16=12,13,0,0,882,32170,0,0,1407,81723,0,0,473,10343,0,0;QS=3,0;MQSB=0.619223;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,195:7:0 0,6,38:2:0 +X 2733 . C A,<*> 0 . DP=25;I16=12,12,0,1,835,30063,13,169,1378,80882,29,841,448,9744,25,625;QS=2.64865,0.351351,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.619223;BQB=1;MQ0F=0 PL:DP:DV 0,48,255,48,255,255:16:0 0,21,187,21,187,187:7:0 7,0,18,10,21,28:2:1 +X 2734 . C <*> 0 . DP=25;I16=12,12,0,0,890,33726,0,0,1378,80882,0,0,449,9797,0,0;QS=3,0;MQSB=0.786628;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,208:8:0 0,3,39:1:0 +X 2735 . T <*> 0 . DP=26;I16=13,12,0,0,955,36875,0,0,1438,84482,0,0,451,9877,0,0;QS=3,0;MQSB=0.778801;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,228:8:0 0,3,41:1:0 +X 2736 . C <*> 0 . DP=26;I16=13,11,0,0,921,35553,0,0,1409,83641,0,0,428,9308,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,220:8:0 0,3,33:1:0 +X 2737 . T <*> 0 . DP=26;I16=13,13,0,0,967,36581,0,0,1467,85323,0,0,475,10403,0,0;QS=3,0;MQSB=0.606531;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,228:8:0 0,6,64:2:0 +X 2738 . T <*> 0 . DP=26;I16=13,13,0,0,895,31873,0,0,1467,85323,0,0,474,10374,0,0;QS=3,0;MQSB=0.606531;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,201:8:0 0,6,47:2:0 +X 2739 . A <*> 0 . DP=26;I16=13,12,0,0,871,31051,0,0,1407,81723,0,0,448,9698,0,0;QS=3,0;MQSB=0.569783;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,224:8:0 0,9,78:3:0 +X 2740 . C <*> 0 . DP=26;I16=14,11,0,0,952,36456,0,0,1438,84482,0,0,448,9674,0,0;QS=3,0;MQSB=0.745495;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,216:8:0 0,6,71:2:0 +X 2741 . C <*> 0 . DP=26;I16=14,11,0,0,945,36141,0,0,1438,84482,0,0,448,9678,0,0;QS=3,0;MQSB=0.745495;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,215:8:0 0,6,75:2:0 +X 2742 . A <*> 0 . DP=27;I16=15,12,0,0,949,34263,0,0,1527,88923,0,0,472,10284,0,0;QS=3,0;MQSB=0.547344;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,230:9:0 0,9,92:3:0 +X 2743 . T <*> 0 . DP=27;I16=15,12,0,0,955,34479,0,0,1527,88923,0,0,471,10243,0,0;QS=3,0;MQSB=0.547344;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,224:9:0 0,9,99:3:0 +X 2744 . C <*> 0 . DP=26;I16=15,10,0,0,955,36951,0,0,1438,84482,0,0,445,9557,0,0;QS=3,0;MQSB=0.707404;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,234:9:0 0,6,76:2:0 +X 2745 . T <*> 0 . DP=26;I16=15,11,0,0,962,36786,0,0,1467,85323,0,0,469,10151,0,0;QS=3,0;MQSB=0.505697;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,243:9:0 0,9,104:3:0 +X 2746 . A <*> 0 . DP=26;I16=15,10,0,0,912,33536,0,0,1438,84482,0,0,443,9525,0,0;QS=3,0;MQSB=0.707404;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,235:9:0 0,6,78:2:0 +X 2747 . A <*> 0 . DP=26;I16=15,11,0,0,945,35117,0,0,1467,85323,0,0,467,10179,0,0;QS=3,0;MQSB=0.505697;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,238:9:0 0,9,96:3:0 +X 2748 . T <*> 0 . DP=27;I16=15,12,0,0,1005,37901,0,0,1527,88923,0,0,465,10187,0,0;QS=3,0;MQSB=0.547344;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,246:9:0 0,9,103:3:0 +X 2749 . C <*> 0 . DP=26;I16=14,12,0,0,975,37353,0,0,1467,85323,0,0,463,10123,0,0;QS=3,0;MQSB=0.558035;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,232:9:0 0,9,98:3:0 +X 2750 . T <*> 0 . DP=26;I16=15,11,0,0,982,37714,0,0,1498,88082,0,0,462,10086,0,0;QS=3,0;MQSB=0.738577;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,227:8:0 0,12,130:4:0 +X 2751 . G <*> 0 . DP=26;I16=15,10,0,0,945,36031,0,0,1469,87241,0,0,437,9451,0,0;QS=3,0;MQSB=0.9171;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,205:8:0 0,9,103:3:0 +X 2752 . T <*> 0 . DP=26;I16=15,11,0,0,870,30288,0,0,1498,88082,0,0,460,9998,0,0;QS=3,0;MQSB=0.738577;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,189:8:0 0,12,119:4:0 +X 2753 . G <*> 0 . DP=26;I16=15,11,0,0,867,30913,0,0,1498,88082,0,0,458,9948,0,0;QS=3,0;MQSB=0.738577;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,202:8:0 0,12,116:4:0 +X 2754 . C <*> 0 . DP=25;I16=14,10,0,0,873,32607,0,0,1409,83641,0,0,436,9484,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,205:8:0 0,9,104:3:0 +X 2755 . C <*> 0 . DP=25;I16=14,10,0,0,865,32243,0,0,1409,83641,0,0,436,9528,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,209:8:0 0,9,97:3:0 +X 2756 . C <*> 0 . DP=25;I16=14,9,0,0,838,31276,0,0,1380,82800,0,0,411,8971,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,204:8:0 0,9,97:3:0 +X 2757 . T <*> 0 . DP=25;I16=14,11,0,0,904,33980,0,0,1438,84482,0,0,455,10011,0,0;QS=3,0;MQSB=0.745495;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,212:7:0 0,15,147:5:0 +X 2758 . T <*> 0 . DP=25;I16=14,10,0,0,841,30293,0,0,1409,83641,0,0,439,9801,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,195:7:0 0,12,133:4:0 +X 2759 . A <*> 0 . DP=25;I16=14,11,0,0,884,31728,0,0,1438,84482,0,0,457,10195,0,0;QS=3,0;MQSB=0.745495;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,192:7:0 0,15,147:5:0 +X 2760 . T <*> 0 . DP=25;I16=14,11,0,0,907,33965,0,0,1438,84482,0,0,457,10275,0,0;QS=3,0;MQSB=0.745495;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,204:7:0 0,15,150:5:0 +X 2761 . T <*> 0 . DP=23;I16=13,9,0,0,838,32530,0,0,1289,76441,0,0,444,10130,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,185:6:0 0,12,141:4:0 +X 2762 . T <*> 0 . DP=24;I16=13,11,0,0,869,32261,0,0,1378,80882,0,0,459,10395,0,0;QS=3,0;MQSB=0.75304;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,178:6:0 0,18,177:6:0 +X 2763 . C A,<*> 0 . DP=24;I16=13,10,0,1,843,31711,13,169,1349,80041,29,841,448,10290,12,144;QS=2.93333,0.0666667,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.75304;BQB=1;MQ0F=0 PL:DP:DV 0,36,255,36,255,255:12:0 0,18,170,18,170,170:6:0 0,5,147,15,150,153:6:1 +X 2764 . C <*> 0 . DP=24;I16=13,10,0,0,854,32376,0,0,1349,80041,0,0,450,10374,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,163:6:0 0,15,162:5:0 +X 2765 . T <*> 0 . DP=24;I16=12,11,0,0,853,32173,0,0,1318,77282,0,0,457,10469,0,0;QS=3,0;MQSB=0.7613;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,154:5:0 0,18,189:6:0 +X 2766 . C <*> 0 . DP=24;I16=12,11,0,0,887,34485,0,0,1349,80041,0,0,448,10398,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,160:5:0 0,18,186:6:0 +X 2767 . T <*> 0 . DP=24;I16=12,12,0,0,905,34757,0,0,1378,80882,0,0,458,10510,0,0;QS=3,0;MQSB=0.786628;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,153:5:0 0,21,217:7:0 +X 2768 . G <*> 0 . DP=23;I16=11,11,0,0,852,33258,0,0,1289,76441,0,0,452,10462,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,141:5:0 0,18,197:6:0 +X 2769 . C <*> 0 . DP=23;I16=11,12,0,0,832,31390,0,0,1318,77282,0,0,459,10481,0,0;QS=3,0;MQSB=0.795196;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,142:5:0 0,21,202:7:0 +X 2770 . T <*> 0 . DP=23;I16=11,12,0,0,828,30854,0,0,1318,77282,0,0,459,10471,0,0;QS=3,0;MQSB=0.795196;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,152:5:0 0,21,199:7:0 +X 2771 . T <*> 0 . DP=23;I16=11,11,0,0,817,30957,0,0,1258,73682,0,0,454,10456,0,0;QS=3,0;MQSB=0.770381;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,154:5:0 0,18,198:6:0 +X 2772 . T <*> 0 . DP=23;I16=11,12,0,0,856,32206,0,0,1318,77282,0,0,459,10511,0,0;QS=3,0;MQSB=0.795196;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,160:5:0 0,21,210:7:0 +X 2773 . A <*> 0 . DP=23;I16=11,12,0,0,828,30664,0,0,1318,77282,0,0,459,10561,0,0;QS=3,0;MQSB=0.795196;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,140:5:0 0,21,209:7:0 +X 2774 . G <*> 0 . DP=22;I16=11,11,0,0,843,32715,0,0,1258,73682,0,0,458,10530,0,0;QS=3,0;MQSB=0.770381;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,154:5:0 0,21,207:7:0 +X 2775 . T <*> 0 . DP=22;I16=10,11,0,0,748,27720,0,0,1198,70082,0,0,432,9892,0,0;QS=3,0;MQSB=0.780412;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,12,115:4:0 0,21,203:7:0 +X 2776 . G <*> 0 . DP=22;I16=12,10,0,0,803,30251,0,0,1289,76441,0,0,456,10470,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,135:5:0 0,21,210:7:0 +X 2777 . A <*> 0 . DP=22;I16=12,10,0,0,852,33524,0,0,1289,76441,0,0,456,10438,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,148:5:0 0,21,220:7:0 +X 2778 . G <*> 0 . DP=23;I16=12,11,0,0,861,33049,0,0,1349,80041,0,0,456,10422,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,154:5:0 0,21,224:7:0 +X 2779 . G <*> 0 . DP=23;I16=11,11,0,0,834,32014,0,0,1289,76441,0,0,432,9798,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,136:4:0 0,21,219:7:0 +X 2780 . A <*> 0 . DP=23;I16=11,11,0,0,792,29162,0,0,1289,76441,0,0,433,9817,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,33,244:11:0 0,12,133:4:0 0,21,215:7:0 +X 2781 . A <*> 0 . DP=23;I16=11,11,0,0,844,33092,0,0,1289,76441,0,0,441,10141,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,15,151:5:0 0,21,233:7:0 +X 2782 . G <*> 0 . DP=23;I16=12,11,0,0,840,31826,0,0,1349,80041,0,0,458,10438,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,154:5:0 0,21,218:7:0 +X 2783 . A <*> 0 . DP=23;I16=11,11,0,0,860,33888,0,0,1289,76441,0,0,432,9790,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,142:4:0 0,21,230:7:0 +X 2784 . G <*> 0 . DP=23;I16=12,11,0,0,860,33092,0,0,1349,80041,0,0,456,10410,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,143:5:0 0,21,212:7:0 +X 2785 . G <*> 0 . DP=23;I16=11,11,0,0,797,29747,0,0,1289,76441,0,0,429,9749,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,134:4:0 0,21,204:7:0 +X 2786 . C <*> 0 . DP=24;I16=12,12,0,0,831,29497,0,0,1409,83641,0,0,451,10309,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,141:5:0 0,21,199:7:0 +X 2787 . C <*> 0 . DP=24;I16=11,12,0,0,792,28454,0,0,1349,80041,0,0,424,9642,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,36,252:12:0 0,12,127:4:0 0,21,200:7:0 +X 2788 . C <*> 0 . DP=23;I16=11,11,0,0,791,29517,0,0,1289,76441,0,0,421,9523,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,125:4:0 0,21,209:7:0 +X 2789 . C <*> 0 . DP=24;I16=13,11,0,0,880,33470,0,0,1409,83641,0,0,443,10051,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,150:5:0 0,21,226:7:0 +X 2790 . T <*> 0 . DP=23;I16=13,10,0,0,886,34738,0,0,1349,80041,0,0,442,9976,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,165:5:0 0,21,227:7:0 +X 2791 . G <*> 0 . DP=23;I16=13,10,0,0,873,34037,0,0,1349,80041,0,0,441,9923,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,155:5:0 0,21,226:7:0 +X 2792 . G <*> 0 . DP=23;I16=13,10,0,0,832,30870,0,0,1349,80041,0,0,438,9792,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,15,146:5:0 0,21,221:7:0 +X 2793 . T <*> 0 . DP=23;I16=13,10,0,0,827,30693,0,0,1349,80041,0,0,435,9683,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,33,247:11:0 0,15,157:5:0 0,21,214:7:0 +X 2794 . C <*> 0 . DP=22;I16=12,10,0,0,786,29122,0,0,1289,76441,0,0,433,9595,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,145:5:0 0,21,201:7:0 +X 2795 . C <*> 0 . DP=22;I16=11,10,0,0,814,31804,0,0,1229,72841,0,0,428,9518,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,15,159:5:0 0,21,222:7:0 +X 2796 . A <*> 0 . DP=22;I16=11,10,0,0,762,28412,0,0,1229,72841,0,0,427,9475,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,27,221:9:0 0,15,156:5:0 0,21,211:7:0 +X 2797 . T <*> 0 . DP=22;I16=12,10,0,0,792,29116,0,0,1289,76441,0,0,427,9451,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,15,148:5:0 0,21,214:7:0 +X 2798 . G <*> 0 . DP=22;I16=12,10,0,0,817,31105,0,0,1289,76441,0,0,424,9394,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,152:5:0 0,21,205:7:0 +X 2799 . A <*> 0 . DP=21;I16=11,10,0,0,788,30210,0,0,1229,72841,0,0,421,9309,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,27,220:9:0 0,15,167:5:0 0,21,218:7:0 +X 2800 . A <*> 0 . DP=21;I16=11,10,0,0,836,33616,0,0,1229,72841,0,0,418,9246,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,27,237:9:0 0,15,164:5:0 0,21,237:7:0 +X 2801 . G <*> 0 . DP=21;I16=11,10,0,0,792,30182,0,0,1229,72841,0,0,415,9205,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,27,234:9:0 0,15,157:5:0 0,21,214:7:0 +X 2802 . G <*> 0 . DP=21;I16=11,9,0,0,729,27275,0,0,1169,69241,0,0,387,8559,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,24,229:8:0 0,15,135:5:0 0,21,215:7:0 +X 2803 . G <*> 0 . DP=21;I16=11,10,0,0,737,26709,0,0,1229,72841,0,0,406,9036,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,15,125:5:0 0,21,207:7:0 +X 2804 . G <*> 0 . DP=21;I16=11,10,0,0,727,26103,0,0,1229,72841,0,0,400,8908,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,27,218:9:0 0,15,129:5:0 0,21,210:7:0 +X 2805 . C <*> 0 . DP=21;I16=10,10,0,0,714,26194,0,0,1169,69241,0,0,372,8316,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,27,229:9:0 0,12,111:4:0 0,21,205:7:0 +X 2806 . C <*> 0 . DP=20;I16=11,8,0,0,682,25074,0,0,1109,65641,0,0,379,8611,0,0;QS=3,0;MQSB=0.902014;MQ0F=0 PL:DP:DV 0,24,215:8:0 0,15,138:5:0 0,18,191:6:0 +X 2807 . T <*> 0 . DP=20;I16=11,9,0,0,755,29373,0,0,1169,69241,0,0,384,8640,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,15,152:5:0 0,21,227:7:0 +X 2808 . T <*> 0 . DP=20;I16=11,9,0,0,749,28383,0,0,1169,69241,0,0,379,8587,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,24,209:8:0 0,15,157:5:0 0,21,225:7:0 +X 2809 . T <*> 0 . DP=20;I16=11,8,0,0,697,26019,0,0,1109,65641,0,0,349,7927,0,0;QS=3,0;MQSB=0.902014;MQ0F=0 PL:DP:DV 0,21,189:7:0 0,15,148:5:0 0,21,226:7:0 +X 2810 . C <*> 0 . DP=20;I16=12,8,0,0,754,28900,0,0,1169,69241,0,0,368,8436,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,24,229:8:0 0,15,150:5:0 0,21,215:7:0 +X 2811 . A <*> 0 . DP=19;I16=11,8,0,0,759,30405,0,0,1109,65641,0,0,364,8340,0,0;QS=3,0;MQSB=0.902014;MQ0F=0 PL:DP:DV 0,21,209:7:0 0,15,166:5:0 0,21,228:7:0 +X 2812 . G <*> 0 . DP=20;I16=11,9,0,0,758,29062,0,0,1169,69241,0,0,359,8213,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,24,229:8:0 0,15,150:5:0 0,21,216:7:0 +X 2813 . A <*> 0 . DP=19;I16=11,8,0,0,702,27106,0,0,1140,68400,0,0,356,8104,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,195:7:0 0,15,160:5:0 0,21,217:7:0 +X 2814 . G <*> 0 . DP=19;I16=11,8,0,0,703,26579,0,0,1140,68400,0,0,353,8013,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,217:7:0 0,15,147:5:0 0,21,204:7:0 +X 2815 . A <*> 0 . DP=19;I16=10,7,0,0,597,21979,0,0,1020,61200,0,0,326,7470,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,170:6:0 0,12,122:4:0 0,21,208:7:0 +X 2816 . C <*> 0 . DP=19;I16=11,8,0,0,630,21880,0,0,1140,68400,0,0,343,7685,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,193:7:0 0,15,134:5:0 0,21,180:7:0 +X 2817 . G <*> 0 . DP=20;I16=11,8,0,0,612,20368,0,0,1140,68400,0,0,339,7547,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,200:7:0 0,15,115:5:0 0,21,178:7:0 +X 2818 . G <*> 0 . DP=20;I16=11,8,0,0,688,25280,0,0,1140,68400,0,0,335,7377,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,216:7:0 0,15,132:5:0 0,21,206:7:0 +X 2819 . G <*> 0 . DP=20;I16=11,8,0,0,696,25880,0,0,1140,68400,0,0,331,7227,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,222:7:0 0,15,142:5:0 0,21,195:7:0 +X 2820 . G <*> 0 . DP=20;I16=10,8,0,0,624,22228,0,0,1080,64800,0,0,320,7048,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,205:7:0 0,12,119:4:0 0,21,188:7:0 +X 2821 . A <*> 0 . DP=20;I16=9,7,0,0,496,16222,0,0,960,57600,0,0,279,6157,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,159:6:0 0,9,93:3:0 0,21,171:7:0 +X 2822 . C <*> 0 . DP=19;I16=8,9,0,0,543,18163,0,0,1020,61200,0,0,310,7064,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,203:7:0 0,9,79:3:0 0,21,168:7:0 +X 2823 . C <*> 0 . DP=18;I16=9,7,0,0,550,19506,0,0,960,57600,0,0,300,6640,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,201:7:0 0,6,58:2:0 0,21,192:7:0 +X 2824 . C <*> 0 . DP=18;I16=9,7,0,0,584,21560,0,0,960,57600,0,0,299,6567,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,219:8:0 0,3,37:1:0 0,21,210:7:0 +X 2825 . C <*> 0 . DP=18;I16=9,8,0,0,606,22286,0,0,1020,61200,0,0,324,7134,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,234:8:0 0,3,37:1:0 0,24,208:8:0 +X 2826 . T <*> 0 . DP=18;I16=9,8,0,0,604,21766,0,0,1020,61200,0,0,323,7043,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,222:8:0 0,3,33:1:0 0,24,220:8:0 +X 2827 . G <*> 0 . DP=18;I16=9,8,0,0,597,21643,0,0,1020,61200,0,0,322,6970,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,230:8:0 0,3,28:1:0 0,24,214:8:0 +X 2828 . A <*> 0 . DP=20;I16=9,9,0,0,598,20740,0,0,1080,64800,0,0,321,6915,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,213:9:0 0,3,36:1:0 0,24,219:8:0 +X 2829 . G <*> 0 . DP=20;I16=9,9,0,0,649,23719,0,0,1080,64800,0,0,305,6591,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,239:8:0 0,3,31:1:0 0,27,227:9:0 +X 2830 . G <*> 0 . DP=20;I16=9,10,0,0,661,23841,0,0,1140,68400,0,0,323,6867,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,248:9:0 0,3,34:1:0 0,27,222:9:0 +X 2831 . A <*> 0 . DP=21;I16=10,10,0,0,682,24052,0,0,1200,72000,0,0,324,6876,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,223:9:0 0,3,34:1:0 0,30,254:10:0 +X 2832 . G <*> 0 . DP=21;I16=10,8,0,0,626,22384,0,0,1080,64800,0,0,281,5883,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,230:8:0 0,3,31:1:0 0,27,223:9:0 +X 2833 . C <*> 0 . DP=21;I16=10,10,0,0,712,25708,0,0,1200,72000,0,0,327,6915,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,3,37:1:0 0,30,255:10:0 +X 2834 . C <*> 0 . DP=21;I16=10,9,0,0,674,24470,0,0,1140,68400,0,0,306,6464,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,230:8:0 0,3,36:1:0 0,30,243:10:0 +X 2835 . C <*> 0 . DP=20;I16=9,9,0,0,617,21835,0,0,1080,64800,0,0,305,6381,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,202:8:0 0,3,39:1:0 0,27,235:9:0 +X 2836 . C <*> 0 . DP=20;I16=9,9,0,0,580,19624,0,0,1080,64800,0,0,306,6412,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,206:8:0 0,3,39:1:0 0,27,200:9:0 +X 2837 . G <*> 0 . DP=21;I16=9,10,0,0,558,17614,0,0,1140,68400,0,0,330,7086,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,207:9:0 0,3,31:1:0 0,27,193:9:0 +X 2838 . A <*> 0 . DP=20;I16=9,10,0,0,640,22674,0,0,1140,68400,0,0,331,7065,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,245:9:0 0,3,17:1:0 0,27,220:9:0 +X 2839 . G <*> 0 . DP=20;I16=9,8,0,0,623,23267,0,0,1020,61200,0,0,282,5816,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,248:8:0 0,3,26:1:0 0,24,212:8:0 +X 2840 . C <*> 0 . DP=20;I16=9,10,0,0,644,22798,0,0,1140,68400,0,0,333,7089,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,3,32:1:0 0,27,227:9:0 +X 2841 . A <*> 0 . DP=20;I16=9,9,0,0,675,25801,0,0,1080,64800,0,0,309,6509,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,252:9:0 0,3,35:1:0 0,24,234:8:0 +X 2842 . G <*> 0 . DP=20;I16=9,10,0,0,688,25554,0,0,1140,68400,0,0,332,7056,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,3,31:1:0 0,27,233:9:0 +X 2843 . C <*> 0 . DP=20;I16=8,10,0,0,651,23969,0,0,1080,64800,0,0,309,6517,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,0,0:0:0 0,24,211:8:0 +X 2844 . A <*> 0 . DP=20;I16=8,11,0,0,685,25399,0,0,1140,68400,0,0,331,6969,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,0,0:0:0 0,27,231:9:0 +X 2845 . G <*> 0 . DP=20;I16=8,10,0,0,673,25399,0,0,1080,64800,0,0,311,6561,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,0,0:0:0 0,24,228:8:0 +X 2846 . C <*> 0 . DP=20;I16=8,10,0,0,617,22007,0,0,1080,64800,0,0,311,6577,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,0,0:0:0 0,24,218:8:0 +X 2847 . C <*> 0 . DP=20;I16=7,11,0,0,580,19468,0,0,1080,64800,0,0,321,6917,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,241:10:0 0,0,0:0:0 0,24,187:8:0 +X 2848 . G <*> 0 . DP=19;I16=7,10,0,0,542,17884,0,0,1020,61200,0,0,323,6999,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,218:9:0 0,0,0:0:0 0,24,191:8:0 +X 2849 . T <*> 0 . DP=19;I16=7,11,0,0,609,21717,0,0,1080,64800,0,0,341,7357,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,231:9:0 0,0,0:0:0 0,27,214:9:0 +X 2850 . C <*> 0 . DP=19;I16=7,11,0,0,574,18980,0,0,1080,64800,0,0,343,7461,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,234:9:0 0,0,0:0:0 0,27,188:9:0 +X 2851 . G <*> 0 . DP=17;I16=6,11,0,0,589,20831,0,0,1020,61200,0,0,346,7584,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,0,0:0:0 0,24,194:8:0 +X 2852 . T <*> 0 . DP=17;I16=6,11,0,0,625,23241,0,0,1020,61200,0,0,348,7676,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,0,0:0:0 0,24,214:8:0 +X 2853 . G <*> 0 . DP=17;I16=6,11,0,0,635,23949,0,0,1020,61200,0,0,349,7739,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,0,0:0:0 0,24,202:8:0 +X 2854 . T <*> 0 . DP=17;I16=6,11,0,0,602,21990,0,0,1020,61200,0,0,348,7722,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,0,0:0:0 0,24,207:8:0 +X 2855 . C <*> 0 . DP=17;I16=6,10,0,0,577,21539,0,0,960,57600,0,0,337,7623,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,0,0:0:0 0,21,185:7:0 +X 2856 . T <*> 0 . DP=17;I16=6,8,0,0,530,20570,0,0,840,50400,0,0,289,6507,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,252:9:0 0,0,0:0:0 0,15,167:5:0 +X 2857 . C <*> 0 . DP=18;I16=6,10,0,0,577,21641,0,0,960,57600,0,0,336,7664,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,0,0:0:0 0,21,185:7:0 +X 2858 . A <*> 0 . DP=19;I16=6,12,0,0,634,23006,0,0,1080,64800,0,0,355,8081,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,254:10:0 0,3,39:1:0 0,21,185:7:0 +X 2859 . C <*> 0 . DP=19;I16=6,13,0,0,646,23056,0,0,1140,68400,0,0,361,8139,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,3,26:1:0 0,24,194:8:0 +X 2860 . C <*> 0 . DP=19;I16=6,13,0,0,655,23687,0,0,1140,68400,0,0,360,8166,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,251:10:0 0,3,37:1:0 0,24,200:8:0 +X 2861 . C <*> 0 . DP=20;I16=7,12,0,0,708,26756,0,0,1140,68400,0,0,333,7537,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,38:1:0 0,21,203:7:0 +X 2862 . A <*> 0 . DP=20;I16=6,13,0,0,749,29753,0,0,1140,68400,0,0,332,7554,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,3,43:1:0 0,24,225:8:0 +X 2863 . G <*> 0 . DP=19;I16=7,12,0,0,707,26901,0,0,1140,68400,0,0,356,8166,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,35:1:0 0,21,195:7:0 +X 2864 . G <*> 0 . DP=19;I16=7,11,0,0,677,25833,0,0,1080,64800,0,0,352,8070,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,36:1:0 0,18,185:6:0 +X 2865 . G <*> 0 . DP=19;I16=7,12,0,0,671,24569,0,0,1140,68400,0,0,350,7994,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,27:1:0 0,21,193:7:0 +X 2866 . T <*> 0 . DP=18;I16=6,11,0,0,591,21071,0,0,1020,61200,0,0,338,7834,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,32:1:0 0,15,147:5:0 +X 2867 . G <*> 0 . DP=18;I16=7,11,0,0,655,24279,0,0,1080,64800,0,0,347,7889,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,58:2:0 0,15,150:5:0 +X 2868 . T <*> 0 . DP=18;I16=7,11,0,0,640,23702,0,0,1080,64800,0,0,347,7859,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,68:2:0 0,15,157:5:0 +X 2869 . C <*> 0 . DP=18;I16=7,11,0,0,655,24737,0,0,1080,64800,0,0,346,7794,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,56:2:0 0,15,165:5:0 +X 2870 . T <*> 0 . DP=18;I16=7,11,0,0,700,27480,0,0,1080,64800,0,0,345,7743,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,70:2:0 0,15,176:5:0 +X 2871 . G <*> 0 . DP=18;I16=7,11,0,0,700,27554,0,0,1080,64800,0,0,344,7706,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,68:2:0 0,15,172:5:0 +X 2872 . A <*> 0 . DP=18;I16=7,11,0,0,651,23869,0,0,1080,64800,0,0,343,7683,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,66:2:0 0,15,171:5:0 +X 2873 . A <*> 0 . DP=18;I16=7,11,0,0,664,25000,0,0,1080,64800,0,0,342,7674,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,61:2:0 0,15,159:5:0 +X 2874 . A <*> 0 . DP=18;I16=7,11,0,0,636,23286,0,0,1080,64800,0,0,341,7679,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,57:2:0 0,15,162:5:0 +X 2875 . C <*> 0 . DP=18;I16=7,11,0,0,664,25148,0,0,1080,64800,0,0,340,7698,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,63:2:0 0,15,166:5:0 +X 2876 . A <*> 0 . DP=18;I16=6,11,0,0,666,26684,0,0,1020,61200,0,0,314,7106,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,6,74:2:0 0,15,185:5:0 +X 2877 . G <*> 0 . DP=17;I16=6,11,0,0,659,26009,0,0,1020,61200,0,0,339,7777,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,67:2:0 0,12,148:4:0 +X 2878 . A <*> 0 . DP=17;I16=7,10,0,0,628,23656,0,0,1020,61200,0,0,340,7834,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,6,69:2:0 0,15,166:5:0 +X 2879 . T <*> 0 . DP=18;I16=7,11,0,0,671,25359,0,0,1080,64800,0,0,342,7902,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,9,96:3:0 0,15,175:5:0 +X 2880 . G <*> 0 . DP=19;I16=8,11,0,0,708,26694,0,0,1140,68400,0,0,345,7983,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,118:4:0 0,15,173:5:0 +X 2881 . T <*> 0 . DP=19;I16=6,11,0,0,618,23304,0,0,1020,61200,0,0,299,6829,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,209:8:0 0,12,124:4:0 0,15,178:5:0 +X 2882 . G <*> 0 . DP=19;I16=8,11,0,0,700,26464,0,0,1140,68400,0,0,353,8191,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,118:4:0 0,15,176:5:0 +X 2883 . G <*> 0 . DP=19;I16=8,11,0,0,707,26939,0,0,1140,68400,0,0,357,8319,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,121:4:0 0,15,175:5:0 +X 2884 . A <*> 0 . DP=19;I16=7,11,0,0,649,24531,0,0,1080,64800,0,0,335,7787,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,229:9:0 0,12,121:4:0 0,15,181:5:0 +X 2885 . G <*> 0 . DP=19;I16=8,11,0,0,737,29253,0,0,1140,68400,0,0,362,8470,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,113:4:0 0,15,182:5:0 +X 2886 . G A,<*> 0 . DP=18;I16=7,9,1,0,571,21281,20,400,960,57600,60,3600,334,7882,6,36;QS=2.76471,0.235294,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,27,236,27,236,236:9:0 11,0,51,17,54,66:3:1 0,15,171,15,171,171:5:0 +X 2887 . T <*> 0 . DP=19;I16=9,9,0,0,581,20407,0,0,1080,64800,0,0,341,7905,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,213:10:0 0,9,94:3:0 0,15,166:5:0 +X 2888 . C <*> 0 . DP=20;I16=10,10,0,0,714,26630,0,0,1200,72000,0,0,368,8532,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,94:4:0 0,15,159:5:0 +X 2889 . T <*> 0 . DP=19;I16=9,10,0,0,712,27106,0,0,1140,68400,0,0,372,8550,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,114:4:0 0,15,175:5:0 +X 2890 . C <*> 0 . DP=19;I16=9,10,0,0,613,20711,0,0,1140,68400,0,0,376,8584,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,12,95:4:0 0,15,139:5:0 +X 2891 . G <*> 0 . DP=20;I16=9,11,0,0,674,23754,0,0,1200,72000,0,0,380,8634,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,242:10:0 0,15,141:5:0 0,15,143:5:0 +X 2892 . G <*> 0 . DP=21;I16=9,12,0,0,731,26677,0,0,1260,75600,0,0,385,8701,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,142:5:0 0,15,164:5:0 +X 2893 . G <*> 0 . DP=21;I16=9,12,0,0,696,24498,0,0,1260,75600,0,0,389,8687,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,251:11:0 0,15,141:5:0 0,15,150:5:0 +X 2894 . T <*> 0 . DP=21;I16=9,12,0,0,716,25490,0,0,1260,75600,0,0,393,8693,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,137:5:0 0,15,155:5:0 +X 2895 . G <*> 0 . DP=22;I16=9,12,0,0,773,29225,0,0,1260,75600,0,0,372,8094,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,149:6:0 0,15,166:5:0 +X 2896 . A <*> 0 . DP=22;I16=8,12,0,0,732,27684,0,0,1200,72000,0,0,361,7885,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,151:5:0 0,15,163:5:0 +X 2897 . G <*> 0 . DP=22;I16=10,12,0,0,783,28783,0,0,1320,79200,0,0,407,8835,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,161:6:0 0,15,168:5:0 +X 2898 . G <*> 0 . DP=22;I16=10,12,0,0,724,25596,0,0,1320,79200,0,0,412,8926,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,18,143:6:0 0,15,169:5:0 +X 2899 . C <*> 0 . DP=22;I16=8,11,0,0,625,21143,0,0,1140,68400,0,0,356,7640,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,15,130:5:0 0,15,147:5:0 +X 2900 . G <*> 0 . DP=24;I16=11,13,0,0,782,26700,0,0,1440,86400,0,0,420,9078,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,164:6:0 0,15,153:5:0 +X 2901 . T <*> 0 . DP=24;I16=11,13,0,0,821,29195,0,0,1440,86400,0,0,426,9192,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,174:6:0 0,15,166:5:0 +X 2902 . G <*> 0 . DP=24;I16=11,13,0,0,898,34176,0,0,1440,86400,0,0,432,9334,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,171:6:0 0,15,164:5:0 +X 2903 . G <*> 0 . DP=24;I16=11,13,0,0,894,33764,0,0,1440,86400,0,0,437,9455,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,183:6:0 0,15,168:5:0 +X 2904 . C <*> 0 . DP=24;I16=11,13,0,0,892,34010,0,0,1440,86400,0,0,440,9506,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,176:6:0 0,15,169:5:0 +X 2905 . T <*> 0 . DP=25;I16=12,13,0,0,926,34994,0,0,1500,90000,0,0,442,9536,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,175:6:0 0,15,174:5:0 +X 2906 . C <*> 0 . DP=25;I16=12,13,0,0,960,37070,0,0,1500,90000,0,0,444,9544,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,178:6:0 0,15,173:5:0 +X 2907 . A <*> 0 . DP=25;I16=11,13,0,0,933,36707,0,0,1440,86400,0,0,429,9275,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,202:6:0 0,15,170:5:0 +X 2908 . G <*> 0 . DP=25;I16=12,13,0,0,943,36315,0,0,1500,90000,0,0,446,9548,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,167:6:0 0,15,164:5:0 +X 2909 . A <*> 0 . DP=25;I16=10,13,0,0,864,32764,0,0,1380,82800,0,0,425,9105,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,182:6:0 0,15,171:5:0 +X 2910 . T <*> 0 . DP=25;I16=11,13,0,0,870,32054,0,0,1440,86400,0,0,447,9575,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,181:6:0 0,15,166:5:0 +X 2911 . A <*> 0 . DP=25;I16=11,14,0,0,871,31227,0,0,1500,90000,0,0,473,10259,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,174:6:0 0,18,188:6:0 +X 2912 . C <*> 0 . DP=24;I16=11,13,0,0,899,34121,0,0,1440,86400,0,0,474,10298,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,173:6:0 0,18,189:6:0 +X 2913 . A <*> 0 . DP=24;I16=10,13,0,0,879,34357,0,0,1380,82800,0,0,449,9691,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,164:5:0 0,18,199:6:0 +X 2914 . G <*> 0 . DP=24;I16=11,13,0,0,899,34575,0,0,1440,86400,0,0,472,10262,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,170:6:0 0,18,187:6:0 +X 2915 . G <*> 0 . DP=24;I16=11,13,0,0,867,32523,0,0,1440,86400,0,0,470,10236,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,177:6:0 0,18,178:6:0 +X 2916 . G <*> 0 . DP=24;I16=11,12,0,0,813,29935,0,0,1380,82800,0,0,443,9613,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,173:6:0 0,15,155:5:0 +X 2917 . A <*> 0 . DP=25;I16=11,13,0,0,864,31926,0,0,1440,86400,0,0,459,10181,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,185:6:0 0,18,178:6:0 +X 2918 . G <*> 0 . DP=25;I16=13,12,0,0,903,33489,0,0,1500,90000,0,0,462,10122,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,165:6:0 0,18,170:6:0 +X 2919 . T <*> 0 . DP=25;I16=12,12,0,0,837,29647,0,0,1440,86400,0,0,443,9765,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,169:6:0 0,18,178:6:0 +X 2920 . G <*> 0 . DP=25;I16=12,12,0,0,850,31266,0,0,1440,86400,0,0,433,9389,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,132:5:0 0,18,180:6:0 +X 2921 . G <*> 0 . DP=25;I16=13,12,0,0,874,31518,0,0,1500,90000,0,0,455,9951,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,159:6:0 0,18,176:6:0 +X 2922 . C <*> 0 . DP=26;I16=13,12,0,0,872,31374,0,0,1500,90000,0,0,438,9718,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,160:6:0 0,18,172:6:0 +X 2923 . C <*> 0 . DP=26;I16=13,12,0,0,873,31687,0,0,1500,90000,0,0,437,9735,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,172:6:0 0,18,175:6:0 +X 2924 . C <*> 0 . DP=25;I16=13,12,0,0,940,36016,0,0,1500,90000,0,0,449,9921,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,173:6:0 0,18,184:6:0 +X 2925 . A <*> 0 . DP=25;I16=13,12,0,0,912,33580,0,0,1500,90000,0,0,448,9964,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,174:6:0 0,18,189:6:0 +X 2926 . C <*> 0 . DP=25;I16=13,12,0,0,902,33224,0,0,1500,90000,0,0,445,9931,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,176:6:0 0,18,174:6:0 +X 2927 . A <*> 0 . DP=25;I16=12,12,0,0,896,33828,0,0,1440,86400,0,0,417,9295,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,162:5:0 0,18,191:6:0 +X 2928 . G <*> 0 . DP=24;I16=13,11,0,0,862,32078,0,0,1440,86400,0,0,440,9930,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,170:6:0 0,18,161:6:0 +X 2929 . C <*> 0 . DP=23;I16=13,9,0,0,794,29716,0,0,1320,79200,0,0,430,9878,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,153:5:0 0,15,149:5:0 +X 2930 . T <*> 0 . DP=23;I16=13,10,0,0,822,30260,0,0,1380,82800,0,0,438,10006,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,168:6:0 0,15,157:5:0 +X 2931 . C <*> 0 . DP=23;I16=13,10,0,0,803,28963,0,0,1380,82800,0,0,436,10020,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,162:6:0 0,15,140:5:0 +X 2932 . G <*> 0 . DP=22;I16=12,10,0,0,728,25158,0,0,1320,79200,0,0,435,10049,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,171:6:0 0,12,117:4:0 +X 2933 . G <*> 0 . DP=22;I16=11,10,0,0,760,28336,0,0,1260,75600,0,0,430,10034,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,175:6:0 0,12,116:4:0 +X 2934 . C <*> 0 . DP=21;I16=12,9,0,0,759,28241,0,0,1260,75600,0,0,432,10052,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,161:6:0 0,9,104:3:0 +X 2935 . C <*> 0 . DP=21;I16=12,9,0,0,766,28494,0,0,1260,75600,0,0,431,10075,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,178:6:0 0,9,94:3:0 +X 2936 . T <*> 0 . DP=21;I16=11,9,0,0,760,29284,0,0,1200,72000,0,0,429,10063,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,188:6:0 0,9,98:3:0 +X 2937 . G <*> 0 . DP=20;I16=11,9,0,0,728,27374,0,0,1200,72000,0,0,428,10066,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,177:6:0 0,9,79:3:0 +X 2938 . T <*> 0 . DP=20;I16=11,9,0,0,719,26217,0,0,1200,72000,0,0,427,10083,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,188:6:0 0,9,101:3:0 +X 2939 . C <*> 0 . DP=19;I16=11,8,0,0,729,28277,0,0,1140,68400,0,0,427,10113,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,163:5:0 0,9,106:3:0 +X 2940 . T <*> 0 . DP=19;I16=11,8,0,0,739,29133,0,0,1140,68400,0,0,427,10155,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,171:5:0 0,9,109:3:0 +X 2941 . T <*> 0 . DP=19;I16=11,8,0,0,702,26358,0,0,1140,68400,0,0,427,10209,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,170:5:0 0,9,99:3:0 +X 2942 . T <*> 0 . DP=19;I16=11,8,0,0,695,25671,0,0,1140,68400,0,0,427,10275,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,169:5:0 0,9,100:3:0 +X 2943 . G <*> 0 . DP=18;I16=11,6,0,0,621,23187,0,0,1020,61200,0,0,401,9627,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,15,170:5:0 0,9,86:3:0 +X 2944 . A <*> 0 . DP=18;I16=10,7,0,0,642,24406,0,0,1020,61200,0,0,399,9563,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,15,168:5:0 0,9,111:3:0 +X 2945 . A <*> 0 . DP=18;I16=11,7,0,0,637,23199,0,0,1080,64800,0,0,422,10132,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,242:10:0 0,15,152:5:0 0,9,107:3:0 +X 2946 . A <*> 0 . DP=18;I16=11,7,0,0,692,26794,0,0,1080,64800,0,0,420,10084,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,174:5:0 0,9,108:3:0 +X 2947 . G <*> 0 . DP=18;I16=11,7,0,0,639,23329,0,0,1080,64800,0,0,418,10044,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,160:5:0 0,9,78:3:0 +X 2948 . G <*> 0 . DP=19;I16=11,8,0,0,702,26272,0,0,1140,68400,0,0,415,9961,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,163:5:0 0,12,116:4:0 +X 2949 . C <*> 0 . DP=19;I16=10,8,0,0,657,24565,0,0,1080,64800,0,0,388,9260,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,125:4:0 0,12,124:4:0 +X 2950 . C <*> 0 . DP=19;I16=11,8,0,0,667,24359,0,0,1140,68400,0,0,411,9817,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,131:5:0 0,12,115:4:0 +X 2951 . A <*> 0 . DP=20;I16=11,8,0,0,682,24956,0,0,1140,68400,0,0,409,9757,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,15,149:5:0 0,12,133:4:0 +X 2952 . C <*> 0 . DP=20;I16=11,9,0,0,647,21709,0,0,1200,72000,0,0,408,9706,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,128:5:0 0,12,112:4:0 +X 2953 . G <*> 0 . DP=21;I16=11,9,0,0,620,19954,0,0,1200,72000,0,0,407,9665,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,237:11:0 0,15,132:5:0 0,12,111:4:0 +X 2954 . T <*> 0 . DP=21;I16=11,10,0,0,742,26662,0,0,1260,75600,0,0,414,9666,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,175:6:0 0,12,135:4:0 +X 2955 . G <*> 0 . DP=22;I16=11,11,0,0,787,28475,0,0,1320,79200,0,0,412,9568,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,170:6:0 0,12,127:4:0 +X 2956 . A <*> 0 . DP=22;I16=11,11,0,0,747,26449,0,0,1320,79200,0,0,410,9438,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,161:6:0 0,12,125:4:0 +X 2957 . C <*> 0 . DP=22;I16=10,10,0,0,693,24757,0,0,1200,72000,0,0,358,8078,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,143:6:0 0,9,104:3:0 +X 2958 . C <*> 0 . DP=21;I16=11,10,0,0,784,29744,0,0,1260,75600,0,0,407,9237,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,172:6:0 0,12,135:4:0 +X 2959 . T <*> 0 . DP=21;I16=11,10,0,0,791,30411,0,0,1260,75600,0,0,406,9164,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,182:6:0 0,12,139:4:0 +X 2960 . G <*> 0 . DP=21;I16=11,10,0,0,778,29502,0,0,1260,75600,0,0,405,9109,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,178:6:0 0,12,126:4:0 +X 2961 . G <*> 0 . DP=20;I16=10,9,0,0,657,23303,0,0,1140,68400,0,0,380,8446,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,231:10:0 0,18,176:6:0 0,9,111:3:0 +X 2962 . C <*> 0 . DP=21;I16=10,10,0,0,731,27459,0,0,1200,72000,0,0,385,8615,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,151:5:0 0,12,132:4:0 +X 2963 . C <*> 0 . DP=21;I16=10,10,0,0,722,26502,0,0,1200,72000,0,0,378,8274,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,169:6:0 0,9,100:3:0 +X 2964 . C <*> 0 . DP=22;I16=11,10,0,0,752,27740,0,0,1260,75600,0,0,379,8275,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,148:5:0 0,15,151:5:0 +X 2965 . A <*> 0 . DP=22;I16=11,11,0,0,804,29606,0,0,1320,79200,0,0,397,8539,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,176:6:0 0,15,155:5:0 +X 2966 . C <*> 0 . DP=22;I16=11,11,0,0,705,23557,0,0,1320,79200,0,0,396,8468,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,18,146:6:0 0,15,142:5:0 +X 2967 . G <*> 0 . DP=24;I16=11,13,0,0,767,25405,0,0,1440,86400,0,0,393,8325,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,162:6:0 0,18,135:6:0 +X 2968 . G <*> 0 . DP=23;I16=11,12,0,0,812,29824,0,0,1380,82800,0,0,393,8213,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,152:5:0 0,18,162:6:0 +X 2969 . C <*> 0 . DP=23;I16=11,12,0,0,866,32982,0,0,1380,82800,0,0,393,8133,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,151:5:0 0,18,181:6:0 +X 2970 . T <*> 0 . DP=24;I16=11,12,0,0,816,29806,0,0,1380,82800,0,0,393,8085,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,154:5:0 0,18,189:6:0 +X 2971 . G <*> 0 . DP=24;I16=12,12,0,0,878,33010,0,0,1440,86400,0,0,392,7970,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,173:6:0 0,18,184:6:0 +X 2972 . G <*> 0 . DP=24;I16=12,12,0,0,839,30363,0,0,1440,86400,0,0,391,7889,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,175:6:0 0,18,161:6:0 +X 2973 . C <*> 0 . DP=24;I16=12,12,0,0,854,31154,0,0,1440,86400,0,0,390,7842,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,177:6:0 0,18,165:6:0 +X 2974 . A <*> 0 . DP=24;I16=12,12,0,0,869,32231,0,0,1440,86400,0,0,388,7778,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,169:6:0 0,18,174:6:0 +X 2975 . G <*> 0 . DP=24;I16=12,12,0,0,857,31835,0,0,1440,86400,0,0,384,7648,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,173:6:0 0,18,167:6:0 +X 2976 . G <*> 0 . DP=25;I16=13,12,0,0,866,31118,0,0,1500,90000,0,0,380,7554,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,180:7:0 0,18,171:6:0 +X 2977 . T <*> 0 . DP=26;I16=13,12,0,0,760,25216,0,0,1469,87241,0,0,373,7437,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,151:6:0 0,18,155:6:0 +X 2978 . G <*> 0 . DP=25;I16=12,12,0,0,862,31574,0,0,1409,83641,0,0,362,7290,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,168:6:0 0,18,167:6:0 +X 2979 . G <*> 0 . DP=24;I16=12,12,0,0,816,28440,0,0,1409,83641,0,0,370,7340,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,164:6:0 0,15,142:5:0 +X 2980 . G <*> 0 . DP=23;I16=12,11,0,0,834,30882,0,0,1349,80041,0,0,369,7293,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,144:5:0 0,15,148:5:0 +X 2981 . A <*> 0 . DP=23;I16=9,11,0,0,622,20306,0,0,1169,69241,0,0,318,6244,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,30,201:10:0 0,15,145:5:0 0,15,150:5:0 +X 2982 . C <*> 0 . DP=23;I16=10,11,0,0,706,24366,0,0,1229,72841,0,0,340,6884,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,93:3:0 0,15,144:5:0 +X 2983 . C <*> 0 . DP=23;I16=12,11,0,0,781,27427,0,0,1349,80041,0,0,363,7197,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,137:5:0 0,15,142:5:0 +X 2984 . C <*> 0 . DP=23;I16=12,11,0,0,861,32655,0,0,1349,80041,0,0,361,7229,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,154:5:0 0,15,157:5:0 +X 2985 . A <*> 0 . DP=23;I16=12,11,0,0,798,28906,0,0,1349,80041,0,0,359,7293,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,161:5:0 0,15,151:5:0 +X 2986 . G <*> 0 . DP=21;I16=11,10,0,0,701,24335,0,0,1229,72841,0,0,358,7388,0,0;QS=3,0;MQSB=0.939898;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,129:5:0 0,12,126:4:0 +X 2987 . C <*> 0 . DP=21;I16=10,10,0,0,720,26782,0,0,1169,69241,0,0,350,7448,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,136:4:0 0,12,132:4:0 +X 2988 . T <*> 0 . DP=20;I16=10,10,0,0,693,25143,0,0,1169,69241,0,0,358,7612,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,132:5:0 0,12,136:4:0 +X 2989 . G <*> 0 . DP=20;I16=10,10,0,0,708,25886,0,0,1169,69241,0,0,358,7736,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,141:5:0 0,12,125:4:0 +X 2990 . C <*> 0 . DP=20;I16=10,10,0,0,697,25083,0,0,1169,69241,0,0,357,7833,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,149:5:0 0,12,129:4:0 +X 2991 . A <*> 0 . DP=20;I16=10,10,0,0,717,26309,0,0,1169,69241,0,0,356,7952,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,151:5:0 0,12,131:4:0 +X 2992 . G <*> 0 . DP=18;I16=10,8,0,0,625,22505,0,0,1049,62041,0,0,356,8042,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,12,130:4:0 0,12,120:4:0 +X 2993 . G <*> 0 . DP=18;I16=10,8,0,0,646,23620,0,0,1049,62041,0,0,354,8050,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,118:4:0 0,12,123:4:0 +X 2994 . G <*> 0 . DP=18;I16=10,8,0,0,620,21828,0,0,1049,62041,0,0,351,8025,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,30,254:10:0 0,12,115:4:0 0,12,116:4:0 +X 2995 . G <*> 0 . DP=18;I16=10,8,0,0,628,22284,0,0,1049,62041,0,0,348,8018,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,12,110:4:0 0,12,135:4:0 +X 2996 . T <*> 0 . DP=17;I16=8,8,0,0,497,16697,0,0,929,54841,0,0,323,7493,0,0;QS=3,0;MQSB=0.915545;MQ0F=0 PL:DP:DV 0,30,215:10:0 0,9,75:3:0 0,9,107:3:0 +X 2997 . C <*> 0 . DP=17;I16=9,8,0,0,603,21925,0,0,989,58441,0,0,341,7901,0,0;QS=3,0;MQSB=0.928603;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,85:3:0 0,12,115:4:0 +X 2998 . C <*> 0 . DP=17;I16=9,8,0,0,576,19964,0,0,989,58441,0,0,337,7841,0,0;QS=3,0;MQSB=0.928603;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,9,84:3:0 0,12,123:4:0 +X 2999 . A <*> 0 . DP=17;I16=9,8,0,0,599,22077,0,0,989,58441,0,0,333,7797,0,0;QS=3,0;MQSB=0.928603;MQ0F=0 PL:DP:DV 0,30,238:10:0 0,9,109:3:0 0,12,136:4:0 +X 3000 . G <*> 0 . DP=15;I16=8,7,0,0,554,20620,0,0,869,51241,0,0,331,7767,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,24,220:8:0 0,9,102:3:0 0,12,135:4:0 +X 3001 . C <*> 0 . DP=15;I16=7,7,0,0,521,19695,0,0,809,47641,0,0,309,7349,0,0;QS=3,0;MQSB=0.885987;MQ0F=0 PL:DP:DV 0,21,213:7:0 0,9,103:3:0 0,12,128:4:0 +X 3002 . A <*> 0 . DP=15;I16=8,7,0,0,542,20082,0,0,869,51241,0,0,326,7692,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,24,224:8:0 0,9,92:3:0 0,12,139:4:0 +X 3003 . G <*> 0 . DP=15;I16=8,7,0,0,540,19814,0,0,869,51241,0,0,322,7594,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,24,230:8:0 0,9,96:3:0 0,12,120:4:0 +X 3004 . C <*> 0 . DP=15;I16=8,7,0,0,525,19113,0,0,869,51241,0,0,318,7504,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,24,211:8:0 0,9,100:3:0 0,12,129:4:0 +X 3005 . A <*> 0 . DP=14;I16=7,7,0,0,491,17343,0,0,809,47641,0,0,315,7421,0,0;QS=3,0;MQSB=0.885987;MQ0F=0 PL:DP:DV 0,21,197:7:0 0,9,95:3:0 0,12,124:4:0 +X 3006 . C <*> 0 . DP=16;I16=7,8,0,0,516,18376,0,0,869,51241,0,0,312,7344,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,24,200:8:0 0,9,95:3:0 0,12,135:4:0 +X 3007 . C <*> 0 . DP=16;I16=7,8,0,0,553,20853,0,0,869,51241,0,0,310,7274,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,24,214:8:0 0,9,103:3:0 0,12,144:4:0 +X 3008 . C <*> 0 . DP=16;I16=7,8,0,0,576,22238,0,0,869,51241,0,0,308,7212,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,24,228:8:0 0,9,105:3:0 0,12,145:4:0 +X 3009 . A <*> 0 . DP=16;I16=7,8,0,0,493,16739,0,0,869,51241,0,0,306,7158,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,24,200:8:0 0,9,83:3:0 0,12,130:4:0 +X 3010 . C <*> 0 . DP=15;I16=7,7,0,0,534,20464,0,0,809,47641,0,0,300,7096,0,0;QS=3,0;MQSB=0.885987;MQ0F=0 PL:DP:DV 0,21,211:7:0 0,9,106:3:0 0,12,135:4:0 +X 3011 . A <*> 0 . DP=16;I16=7,8,0,0,559,21173,0,0,869,51241,0,0,302,7074,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,24,218:8:0 0,9,104:3:0 0,12,145:4:0 +X 3012 . G <*> 0 . DP=16;I16=7,8,0,0,503,17903,0,0,869,51241,0,0,300,7044,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,24,193:8:0 0,9,93:3:0 0,12,141:4:0 +X 3013 . C <*> 0 . DP=16;I16=7,9,0,0,549,19967,0,0,898,52082,0,0,305,7071,0,0;QS=3,0;MQSB=0.994413;MQ0F=0 PL:DP:DV 0,27,207:9:0 0,9,98:3:0 0,12,141:4:0 +X 3014 . A <*> 0 . DP=18;I16=6,9,0,0,542,20362,0,0,838,48482,0,0,289,6959,0,0;QS=3,0;MQSB=0.984496;MQ0F=0 PL:DP:DV 0,24,195:8:0 0,9,109:3:0 0,12,141:4:0 +X 3015 . G <*> 0 . DP=20;I16=7,9,0,0,549,19441,0,0,929,54841,0,0,311,7547,0,0;QS=3,0;MQSB=0.892753;MQ0F=0 PL:DP:DV 0,24,206:8:0 0,12,116:4:0 0,12,131:4:0 +X 3016 . C <*> 0 . DP=20;I16=7,13,0,0,690,24374,0,0,1138,66482,0,0,337,7783,0,0;QS=3,0;MQSB=0.972138;MQ0F=0 PL:DP:DV 0,33,248:11:0 0,15,136:5:0 0,12,132:4:0 +X 3017 . C A,<*> 0 . DP=20;I16=7,12,0,1,650,23264,23,529,1109,65641,29,841,329,7715,11,121;QS=2.93801,0.0619946,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.972138;BQB=1;MQ0F=0 PL:DP:DV 0,10,224,30,227,236:11:1 0,15,133,15,133,133:5:0 0,12,128,12,128,128:4:0 +X 3018 . A <*> 0 . DP=21;I16=6,10,0,0,475,15057,0,0,929,54841,0,0,295,6991,0,0;QS=3,0;MQSB=0.863243;MQ0F=0 PL:DP:DV 0,27,192:9:0 0,12,111:4:0 0,9,81:3:0 +X 3019 . C <*> 0 . DP=20;I16=6,12,0,0,618,21842,0,0,1049,62041,0,0,336,7818,0,0;QS=3,0;MQSB=0.85394;MQ0F=0 PL:DP:DV 0,30,242:10:0 0,15,129:5:0 0,9,104:3:0 +X 3020 . C <*> 0 . DP=20;I16=6,12,0,0,588,21046,0,0,1049,62041,0,0,340,7888,0,0;QS=3,0;MQSB=0.85394;MQ0F=0 PL:DP:DV 0,30,221:10:0 0,15,129:5:0 0,9,114:3:0 +X 3021 . T <*> 0 . DP=21;I16=5,13,0,0,618,22454,0,0,1049,62041,0,0,343,7921,0,0;QS=3,0;MQSB=0.814433;MQ0F=0 PL:DP:DV 0,30,216:10:0 0,15,147:5:0 0,9,109:3:0 +X 3022 . G <*> 0 . DP=20;I16=5,13,0,0,672,25292,0,0,1049,62041,0,0,348,7968,0,0;QS=3,0;MQSB=0.814433;MQ0F=0 PL:DP:DV 0,30,234:10:0 0,15,153:5:0 0,9,109:3:0 +X 3023 . T G,<*> 0 . DP=20;I16=5,12,0,1,554,19110,18,324,989,58441,60,3600,336,7740,17,289;QS=2.94231,0.0576923,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.814433;BQB=1;MQ0F=0 PL:DP:DV 0,12,191,27,194,199:10:1 0,15,125,15,125,125:5:0 0,9,111,9,111,111:3:0 +X 3024 . G <*> 0 . DP=20;I16=5,14,0,0,684,25122,0,0,1109,65641,0,0,382,8680,0,0;QS=3,0;MQSB=0.810584;MQ0F=0 PL:DP:DV 0,30,235:10:0 0,18,152:6:0 0,9,113:3:0 +X 3025 . G <*> 0 . DP=20;I16=5,14,0,0,625,21465,0,0,1109,65641,0,0,386,8722,0,0;QS=3,0;MQSB=0.810584;MQ0F=0 PL:DP:DV 0,30,225:10:0 0,18,133:6:0 0,9,109:3:0 +X 3026 . C <*> 0 . DP=20;I16=5,13,0,0,632,23132,0,0,1018,59282,0,0,367,8217,0,0;QS=3,0;MQSB=0.925212;MQ0F=0 PL:DP:DV 0,33,235:11:0 0,12,105:4:0 0,9,107:3:0 +X 3027 . A <*> 0 . DP=21;I16=6,15,0,0,693,24199,0,0,1198,70082,0,0,413,9199,0,0;QS=3,0;MQSB=0.940481;MQ0F=0 PL:DP:DV 0,33,222:11:0 0,21,175:7:0 0,9,108:3:0 +X 3028 . G <*> 0 . DP=21;I16=6,15,0,0,753,27935,0,0,1198,70082,0,0,417,9239,0,0;QS=3,0;MQSB=0.940481;MQ0F=0 PL:DP:DV 0,33,241:11:0 0,21,192:7:0 0,9,107:3:0 +X 3029 . G <*> 0 . DP=21;I16=6,15,0,0,787,29949,0,0,1198,70082,0,0,421,9303,0,0;QS=3,0;MQSB=0.940481;MQ0F=0 PL:DP:DV 0,33,251:11:0 0,21,189:7:0 0,9,109:3:0 +X 3030 . G <*> 0 . DP=22;I16=6,16,0,0,720,24728,0,0,1258,73682,0,0,424,9342,0,0;QS=3,0;MQSB=0.934321;MQ0F=0 PL:DP:DV 0,36,229:12:0 0,21,174:7:0 0,9,106:3:0 +X 3031 . A <*> 0 . DP=22;I16=5,16,0,0,693,24631,0,0,1198,70082,0,0,403,8783,0,0;QS=3,0;MQSB=0.902014;MQ0F=0 PL:DP:DV 0,36,222:12:0 0,18,162:6:0 0,9,113:3:0 +X 3032 . G <*> 0 . DP=22;I16=6,15,0,0,727,26093,0,0,1229,72841,0,0,405,8775,0,0;QS=3,0;MQSB=0.843281;MQ0F=0 PL:DP:DV 0,33,237:11:0 0,21,180:7:0 0,9,106:3:0 +X 3033 . G <*> 0 . DP=22;I16=6,15,0,0,697,24039,0,0,1198,70082,0,0,429,9407,0,0;QS=3,0;MQSB=0.940481;MQ0F=0 PL:DP:DV 0,33,235:11:0 0,21,160:7:0 0,9,106:3:0 +X 3034 . A <*> 0 . DP=23;I16=6,14,0,0,617,20947,0,0,1138,66482,0,0,387,8491,0,0;QS=3,0;MQSB=0.947033;MQ0F=0 PL:DP:DV 0,33,203:11:0 0,15,134:5:0 0,12,126:4:0 +X 3035 . G <*> 0 . DP=23;I16=7,13,0,0,641,22007,0,0,1138,66482,0,0,385,8379,0,0;QS=3,0;MQSB=0.972138;MQ0F=0 PL:DP:DV 0,30,208:10:0 0,18,151:6:0 0,12,128:4:0 +X 3036 . C <*> 0 . DP=23;I16=6,15,0,0,688,23652,0,0,1198,70082,0,0,388,8258,0,0;QS=3,0;MQSB=0.940481;MQ0F=0 PL:DP:DV 0,36,216:12:0 0,15,132:5:0 0,12,140:4:0 +X 3037 . T <*> 0 . DP=24;I16=7,16,0,0,797,28671,0,0,1318,77282,0,0,439,9521,0,0;QS=3,0;MQSB=0.955805;MQ0F=0 PL:DP:DV 0,36,242:12:0 0,21,170:7:0 0,12,143:4:0 +X 3038 . T <*> 0 . DP=25;I16=8,17,0,0,815,27469,0,0,1438,84482,0,0,441,9561,0,0;QS=3,0;MQSB=0.966223;MQ0F=0 PL:DP:DV 0,42,249:14:0 0,21,190:7:0 0,12,125:4:0 +X 3039 . G <*> 0 . DP=25;I16=8,17,0,0,780,25946,0,0,1438,84482,0,0,444,9630,0,0;QS=3,0;MQSB=0.966223;MQ0F=0 PL:DP:DV 0,42,249:14:0 0,21,156:7:0 0,12,127:4:0 +X 3040 . T <*> 0 . DP=25;I16=7,15,0,0,701,23777,0,0,1258,73682,0,0,385,8279,0,0;QS=3,0;MQSB=0.961028;MQ0F=0 PL:DP:DV 0,36,239:12:0 0,18,154:6:0 0,12,130:4:0 +X 3041 . G <*> 0 . DP=25;I16=8,16,0,0,824,29228,0,0,1378,80882,0,0,420,8982,0,0;QS=3,0;MQSB=0.970446;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,186:7:0 0,12,135:4:0 +X 3042 . G <*> 0 . DP=25;I16=8,15,0,0,795,28227,0,0,1349,80041,0,0,409,8839,0,0;QS=3,0;MQSB=0.889418;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,148:6:0 0,12,120:4:0 +X 3043 . T <*> 0 . DP=25;I16=8,16,0,0,723,23191,0,0,1378,80882,0,0,435,9415,0,0;QS=3,0;MQSB=0.970446;MQ0F=0 PL:DP:DV 0,39,233:13:0 0,21,151:7:0 0,12,124:4:0 +X 3044 . A C,<*> 0 . DP=26;I16=8,15,0,1,665,20809,15,225,1318,77282,60,3600,392,8498,14,196;QS=2.96104,0.038961,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.970446;BQB=1;MQ0F=0 PL:DP:DV 0,26,216,39,219,220:14:1 0,18,133,18,133,133:6:0 0,12,124,12,124,124:4:0 +X 3045 . C <*> 0 . DP=26;I16=8,16,0,0,754,25232,0,0,1378,80882,0,0,403,8627,0,0;QS=3,0;MQSB=0.970446;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,133:6:0 0,12,122:4:0 +X 3046 . A <*> 0 . DP=25;I16=8,15,0,0,748,26170,0,0,1349,80041,0,0,400,8540,0,0;QS=3,0;MQSB=0.889418;MQ0F=0 PL:DP:DV 0,39,245:13:0 0,18,160:6:0 0,12,141:4:0 +X 3047 . G <*> 0 . DP=25;I16=8,15,0,0,766,26998,0,0,1318,77282,0,0,396,8432,0,0;QS=3,0;MQSB=0.974802;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,143:6:0 0,12,129:4:0 +X 3048 . T <*> 0 . DP=25;I16=8,11,0,0,608,20554,0,0,1109,65641,0,0,320,6762,0,0;QS=3,0;MQSB=0.902014;MQ0F=0 PL:DP:DV 0,30,226:10:0 0,15,128:5:0 0,12,129:4:0 +X 3049 . G <*> 0 . DP=24;I16=8,16,0,0,831,29557,0,0,1378,80882,0,0,426,9068,0,0;QS=3,0;MQSB=0.970446;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,161:6:0 0,9,105:3:0 +X 3050 . G <*> 0 . DP=24;I16=8,14,0,0,729,25093,0,0,1258,73682,0,0,379,8041,0,0;QS=3,0;MQSB=0.979255;MQ0F=0 PL:DP:DV 0,39,253:13:0 0,18,159:6:0 0,9,100:3:0 +X 3051 . A <*> 0 . DP=23;I16=8,15,0,0,724,24200,0,0,1318,77282,0,0,423,9091,0,0;QS=3,0;MQSB=0.974802;MQ0F=0 PL:DP:DV 0,42,243:14:0 0,18,152:6:0 0,9,103:3:0 +X 3052 . C <*> 0 . DP=23;I16=7,13,0,0,612,19876,0,0,1169,69241,0,0,363,7779,0,0;QS=3,0;MQSB=0.962269;MQ0F=0 PL:DP:DV 0,36,226:12:0 0,15,117:5:0 0,9,93:3:0 +X 3053 . A <*> 0 . DP=22;I16=8,11,0,0,616,21288,0,0,1078,62882,0,0,360,7740,0,0;QS=3,0;MQSB=0.992359;MQ0F=0 PL:DP:DV 0,33,234:11:0 0,15,118:5:0 0,9,110:3:0 +X 3054 . G <*> 0 . DP=22;I16=8,14,0,0,761,27617,0,0,1258,73682,0,0,414,8932,0,0;QS=3,0;MQSB=0.979255;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,126:5:0 0,9,99:3:0 +X 3055 . G <*> 0 . DP=22;I16=8,9,0,0,566,19890,0,0,958,55682,0,0,333,7219,0,0;QS=3,0;MQSB=0.998843;MQ0F=0 PL:DP:DV 0,30,228:10:0 0,12,111:4:0 0,9,105:3:0 +X 3056 . C <*> 0 . DP=22;I16=7,14,0,0,701,24685,0,0,1198,70082,0,0,420,9298,0,0;QS=3,0;MQSB=0.966484;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,125:4:0 0,12,122:4:0 +X 3057 . C <*> 0 . DP=23;I16=8,13,0,0,706,24988,0,0,1198,70082,0,0,411,9253,0,0;QS=3,0;MQSB=0.983744;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,128:5:0 0,9,92:3:0 +X 3058 . C <*> 0 . DP=23;I16=9,14,0,0,707,23327,0,0,1318,77282,0,0,429,9471,0,0;QS=3,0;MQSB=0.987676;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,131:5:0 0,12,116:4:0 +X 3059 . T G,<*> 0 . DP=23;I16=9,11,0,1,638,21954,16,256,1169,69241,60,3600,355,7761,22,484;QS=2.95876,0.0412371,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.913101;BQB=1;MQ0F=0 PL:DP:DV 0,22,234,36,237,239:13:1 0,15,144,15,144,144:5:0 0,9,94,9,94,94:3:0 +X 3060 . G <*> 0 . DP=24;I16=9,10,0,0,578,19136,0,0,1109,65641,0,0,324,6992,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,33,221:11:0 0,12,121:4:0 0,12,116:4:0 +X 3061 . C <*> 0 . DP=24;I16=9,15,0,0,770,25918,0,0,1378,80882,0,0,446,10136,0,0;QS=3,0;MQSB=0.984127;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,138:5:0 0,15,145:5:0 +X 3062 . C <*> 0 . DP=23;I16=9,13,0,0,727,25019,0,0,1289,76441,0,0,419,9551,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,137:5:0 0,15,134:5:0 +X 3063 . C <*> 0 . DP=23;I16=9,13,0,0,651,21695,0,0,1258,73682,0,0,415,9511,0,0;QS=3,0;MQSB=0.991121;MQ0F=0 PL:DP:DV 0,36,233:12:0 0,15,130:5:0 0,15,133:5:0 +X 3064 . A <*> 0 . DP=23;I16=9,12,0,0,691,24125,0,0,1198,70082,0,0,385,8815,0,0;QS=3,0;MQSB=0.994334;MQ0F=0 PL:DP:DV 0,36,254:12:0 0,12,118:4:0 0,15,144:5:0 +X 3065 . G <*> 0 . DP=22;I16=7,14,0,0,653,21733,0,0,1198,70082,0,0,426,9986,0,0;QS=3,0;MQSB=0.966484;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,109:4:0 0,12,118:4:0 +X 3066 . A <*> 0 . DP=21;I16=7,10,0,0,501,16143,0,0,989,58441,0,0,326,7598,0,0;QS=3,0;MQSB=0.887766;MQ0F=0 PL:DP:DV 0,27,202:9:0 0,12,109:4:0 0,12,104:4:0 +X 3067 . T <*> 0 . DP=21;I16=7,12,0,0,535,16779,0,0,1078,62882,0,0,373,8787,0,0;QS=3,0;MQSB=0.977926;MQ0F=0 PL:DP:DV 0,36,223:12:0 0,9,82:3:0 0,12,103:4:0 +X 3068 . G <*> 0 . DP=20;I16=7,12,0,0,645,22781,0,0,1109,65641,0,0,396,9312,0,0;QS=3,0;MQSB=0.879351;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,115:4:0 0,9,84:3:0 +X 3069 . G <*> 0 . DP=20;I16=7,10,0,0,468,14412,0,0,989,58441,0,0,346,8070,0,0;QS=3,0;MQSB=0.887766;MQ0F=0 PL:DP:DV 0,33,203:11:0 0,12,102:4:0 0,6,57:2:0 +X 3070 . C <*> 0 . DP=20;I16=6,13,0,0,627,22135,0,0,1078,62882,0,0,414,9878,0,0;QS=3,0;MQSB=0.953977;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,98:3:0 0,9,98:3:0 +X 3071 . C <*> 0 . DP=20;I16=7,13,0,0,715,26563,0,0,1138,66482,0,0,419,9893,0,0;QS=3,0;MQSB=0.972138;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,123:4:0 0,9,98:3:0 +X 3072 . C <*> 0 . DP=20;I16=6,13,0,0,696,25784,0,0,1109,65641,0,0,414,9866,0,0;QS=3,0;MQSB=0.965977;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,128:4:0 0,9,106:3:0 +X 3073 . C <*> 0 . DP=20;I16=6,13,0,0,706,26822,0,0,1109,65641,0,0,414,9872,0,0;QS=3,0;MQSB=0.965977;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,135:4:0 0,9,115:3:0 +X 3074 . C <*> 0 . DP=20;I16=6,13,0,0,724,28052,0,0,1109,65641,0,0,414,9886,0,0;QS=3,0;MQSB=0.965977;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,135:4:0 0,9,116:3:0 +X 3075 . C <*> 0 . DP=21;I16=6,13,0,0,630,21614,0,0,1109,65641,0,0,389,9283,0,0;QS=3,0;MQSB=0.965977;MQ0F=0 PL:DP:DV 0,33,239:11:0 0,15,140:5:0 0,9,94:3:0 +X 3076 . G <*> 0 . DP=21;I16=6,14,0,0,645,21809,0,0,1169,69241,0,0,415,9939,0,0;QS=3,0;MQSB=0.969852;MQ0F=0 PL:DP:DV 0,36,252:12:0 0,15,126:5:0 0,9,91:3:0 +X 3077 . C <*> 0 . DP=20;I16=5,15,0,0,694,25228,0,0,1169,69241,0,0,417,9979,0,0;QS=3,0;MQSB=0.976472;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,116:4:0 0,9,111:3:0 +X 3078 . C <*> 0 . DP=20;I16=5,15,0,0,767,29761,0,0,1169,69241,0,0,420,10028,0,0;QS=3,0;MQSB=0.976472;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,113:4:0 0,9,111:3:0 +X 3079 . T <*> 0 . DP=20;I16=5,15,0,0,749,28479,0,0,1169,69241,0,0,422,10038,0,0;QS=3,0;MQSB=0.976472;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,119:4:0 0,9,116:3:0 +X 3080 . G <*> 0 . DP=21;I16=6,15,0,0,785,29901,0,0,1229,72841,0,0,424,10060,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,124:4:0 0,9,103:3:0 +X 3081 . C <*> 0 . DP=21;I16=6,15,0,0,752,27438,0,0,1229,72841,0,0,425,9997,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,118:4:0 0,9,92:3:0 +X 3082 . C <*> 0 . DP=21;I16=6,15,0,0,787,30211,0,0,1229,72841,0,0,426,9952,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,118:4:0 0,9,112:3:0 +X 3083 . T C,<*> 0 . DP=21;I16=6,14,0,1,764,29458,33,1089,1169,69241,60,3600,401,9249,25,625;QS=2.93666,0.0633397,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.973096;BQB=1;MQ0F=0 PL:DP:DV 0,9,255,39,255,255:14:1 0,12,130,12,130,130:4:0 0,9,113,9,113,113:3:0 +X 3084 . G <*> 0 . DP=23;I16=6,17,0,0,859,32755,0,0,1349,80041,0,0,426,9812,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,118:4:0 0,12,135:4:0 +X 3085 . T <*> 0 . DP=23;I16=6,16,0,0,824,31132,0,0,1289,76441,0,0,426,9718,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,124:4:0 0,12,135:4:0 +X 3086 . G <*> 0 . DP=23;I16=6,17,0,0,853,32429,0,0,1349,80041,0,0,428,9648,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,125:4:0 0,12,131:4:0 +X 3087 . G <*> 0 . DP=23;I16=6,17,0,0,897,35253,0,0,1349,80041,0,0,429,9599,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,130:4:0 0,12,137:4:0 +X 3088 . A <*> 0 . DP=22;I16=6,16,0,0,834,31738,0,0,1289,76441,0,0,431,9571,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,110:3:0 0,12,135:4:0 +X 3089 . A <*> 0 . DP=23;I16=7,16,0,0,919,36903,0,0,1349,80041,0,0,432,9514,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,113:3:0 0,15,175:5:0 +X 3090 . G <*> 0 . DP=23;I16=7,16,0,0,885,34349,0,0,1349,80041,0,0,433,9431,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,103:3:0 0,15,160:5:0 +X 3091 . T <*> 0 . DP=23;I16=7,16,0,0,840,31352,0,0,1349,80041,0,0,434,9374,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,105:3:0 0,15,153:5:0 +X 3092 . T <*> 0 . DP=24;I16=8,16,0,0,895,33673,0,0,1409,83641,0,0,434,9294,0,0;QS=3,0;MQSB=0.970446;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,109:3:0 0,15,165:5:0 +X 3093 . G <*> 0 . DP=25;I16=9,16,0,0,955,37033,0,0,1469,87241,0,0,434,9192,0,0;QS=3,0;MQSB=0.968069;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,133:4:0 0,15,157:5:0 +X 3094 . A <*> 0 . DP=25;I16=9,15,0,0,891,33319,0,0,1409,83641,0,0,425,9019,0,0;QS=3,0;MQSB=0.96464;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,134:4:0 0,15,161:5:0 +X 3095 . C <*> 0 . DP=25;I16=9,15,0,0,891,33469,0,0,1409,83641,0,0,425,8955,0,0;QS=3,0;MQSB=0.96464;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,131:4:0 0,15,163:5:0 +X 3096 . C <*> 0 . DP=25;I16=9,16,0,0,952,36626,0,0,1469,87241,0,0,436,9014,0,0;QS=3,0;MQSB=0.968069;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,121:4:0 0,15,167:5:0 +X 3097 . A <*> 0 . DP=25;I16=9,16,0,0,972,38200,0,0,1469,87241,0,0,436,8984,0,0;QS=3,0;MQSB=0.968069;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,144:4:0 0,15,174:5:0 +X 3098 . G <*> 0 . DP=25;I16=9,16,0,0,959,37269,0,0,1469,87241,0,0,436,8986,0,0;QS=3,0;MQSB=0.968069;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,134:4:0 0,15,166:5:0 +X 3099 . A <*> 0 . DP=25;I16=9,16,0,0,888,32632,0,0,1469,87241,0,0,435,8971,0,0;QS=3,0;MQSB=0.968069;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,124:4:0 0,15,165:5:0 +X 3100 . C <*> 0 . DP=25;I16=9,16,0,0,870,31084,0,0,1469,87241,0,0,434,8990,0,0;QS=3,0;MQSB=0.968069;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,126:4:0 0,15,159:5:0 +X 3101 . C <*> 0 . DP=25;I16=9,16,0,0,960,37090,0,0,1469,87241,0,0,432,8992,0,0;QS=3,0;MQSB=0.968069;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,134:4:0 0,15,161:5:0 +X 3102 . A <*> 0 . DP=26;I16=10,16,0,0,952,35186,0,0,1529,90841,0,0,430,9026,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,134:4:0 0,18,189:6:0 +X 3103 . T <*> 0 . DP=26;I16=10,16,0,0,920,33094,0,0,1529,90841,0,0,427,8993,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,131:4:0 0,18,187:6:0 +X 3104 . C T,<*> 0 . DP=25;I16=8,15,2,0,900,35584,80,3202,1349,80041,120,7200,385,8143,40,850;QS=2.58763,0.412371,0;VDB=0.8;SGB=0.346553;RPB=0.717391;MQB=0.956522;MQSB=0.962269;BQB=0.978261;MQ0F=0 PL:DP:DV 0,48,255,48,255,255:16:0 0,12,144,12,144,144:4:0 59,0,93,68,99,157:5:2 +X 3105 . T <*> 0 . DP=25;I16=10,15,0,0,959,37057,0,0,1469,87241,0,0,422,8976,0,0;QS=3,0;MQSB=0.962269;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,149:4:0 0,15,169:5:0 +X 3106 . G <*> 0 . DP=23;I16=10,13,0,0,881,33891,0,0,1380,82800,0,0,420,8940,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,132:4:0 0,15,167:5:0 +X 3107 . T <*> 0 . DP=24;I16=10,14,0,0,878,32496,0,0,1440,86400,0,0,418,8932,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,132:4:0 0,18,195:6:0 +X 3108 . C <*> 0 . DP=24;I16=10,14,0,0,909,34897,0,0,1440,86400,0,0,417,8953,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,137:4:0 0,18,189:6:0 +X 3109 . A <*> 0 . DP=24;I16=10,14,0,0,905,34249,0,0,1440,86400,0,0,416,9004,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,136:4:0 0,18,195:6:0 +X 3110 . C <*> 0 . DP=24;I16=10,13,0,0,919,37099,0,0,1380,82800,0,0,413,8933,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,105:3:0 0,18,189:6:0 +X 3111 . A <*> 0 . DP=25;I16=10,14,0,0,961,38943,0,0,1440,86400,0,0,410,8888,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,111:3:0 0,18,205:6:0 +X 3112 . G <*> 0 . DP=25;I16=10,14,0,0,958,39370,0,0,1440,86400,0,0,407,8821,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,116:3:0 0,18,191:6:0 +X 3113 . C <*> 0 . DP=25;I16=10,14,0,0,961,39641,0,0,1440,86400,0,0,403,8735,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,112:3:0 0,18,193:6:0 +X 3114 . A <*> 0 . DP=24;I16=10,13,0,0,928,38448,0,0,1380,82800,0,0,400,8680,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,116:3:0 0,18,200:6:0 +X 3115 . G <*> 0 . DP=23;I16=10,12,0,0,872,35800,0,0,1320,79200,0,0,397,8603,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,117:3:0 0,18,195:6:0 +X 3116 . G <*> 0 . DP=23;I16=10,12,0,0,870,35372,0,0,1320,79200,0,0,394,8552,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,108:3:0 0,18,194:6:0 +X 3117 . T <*> 0 . DP=22;I16=9,13,0,0,771,27537,0,0,1320,79200,0,0,399,8575,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,96:3:0 0,18,177:6:0 +X 3118 . A <*> 0 . DP=22;I16=9,13,0,0,813,30285,0,0,1320,79200,0,0,397,8537,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,111:3:0 0,18,193:6:0 +X 3119 . A <*> 0 . DP=22;I16=9,13,0,0,886,35954,0,0,1320,79200,0,0,393,8423,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,120:3:0 0,18,207:6:0 +X 3120 . G <*> 0 . DP=22;I16=9,13,0,0,839,32281,0,0,1320,79200,0,0,389,8333,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,104:3:0 0,18,182:6:0 +X 3121 . A <*> 0 . DP=22;I16=10,12,0,0,777,28399,0,0,1320,79200,0,0,386,8266,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,111:3:0 0,18,194:6:0 +X 3122 . C <*> 0 . DP=22;I16=10,12,0,0,848,33002,0,0,1320,79200,0,0,384,8222,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,110:3:0 0,18,192:6:0 +X 3123 . T <*> 0 . DP=22;I16=10,12,0,0,854,33456,0,0,1320,79200,0,0,382,8202,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,114:3:0 0,18,204:6:0 +X 3124 . C <*> 0 . DP=22;I16=10,11,0,0,882,38286,0,0,1260,75600,0,0,381,8205,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,104:3:0 0,15,178:5:0 +X 3125 . T <*> 0 . DP=22;I16=10,11,0,0,860,36764,0,0,1260,75600,0,0,380,8230,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,106:3:0 0,15,185:5:0 +X 3126 . G <*> 0 . DP=22;I16=10,11,0,0,834,34998,0,0,1260,75600,0,0,379,8277,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,97:3:0 0,15,174:5:0 +X 3127 . C <*> 0 . DP=23;I16=10,11,0,0,847,36381,0,0,1260,75600,0,0,378,8346,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,87:3:0 0,15,175:5:0 +X 3128 . T <*> 0 . DP=22;I16=9,12,0,0,850,35972,0,0,1229,72841,0,0,402,9010,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,107:3:0 0,15,182:5:0 +X 3129 . T <*> 0 . DP=22;I16=9,12,0,0,809,32621,0,0,1229,72841,0,0,401,9067,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,107:3:0 0,15,178:5:0 +X 3130 . T <*> 0 . DP=21;I16=9,10,0,0,744,30322,0,0,1140,68400,0,0,376,8516,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,82:2:0 0,15,169:5:0 +X 3131 . C <*> 0 . DP=21;I16=9,10,0,0,792,34778,0,0,1140,68400,0,0,376,8606,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,83:2:0 0,15,170:5:0 +X 3132 . T <*> 0 . DP=21;I16=9,11,0,0,819,35197,0,0,1169,69241,0,0,400,9288,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,109:3:0 0,15,174:5:0 +X 3133 . G <*> 0 . DP=21;I16=9,11,0,0,800,34016,0,0,1169,69241,0,0,398,9312,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,97:3:0 0,15,166:5:0 +X 3134 . G <*> 0 . DP=22;I16=10,11,0,0,773,30227,0,0,1229,72841,0,0,396,9352,0,0;QS=3,0;MQSB=0.939898;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,97:3:0 0,15,163:5:0 +X 3135 . G <*> 0 . DP=22;I16=9,12,0,0,812,33714,0,0,1229,72841,0,0,396,9408,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,94:3:0 0,12,151:4:0 +X 3136 . C <*> 0 . DP=22;I16=9,12,0,0,811,33469,0,0,1229,72841,0,0,396,9430,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,102:3:0 0,12,140:4:0 +X 3137 . A <*> 0 . DP=22;I16=10,11,0,0,786,31226,0,0,1229,72841,0,0,396,9416,0,0;QS=3,0;MQSB=0.939898;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,95:3:0 0,12,142:4:0 +X 3138 . A <*> 0 . DP=21;I16=9,11,0,0,720,28200,0,0,1169,69241,0,0,398,9414,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,98:3:0 0,12,147:4:0 +X 3139 . C <*> 0 . DP=21;I16=9,11,0,0,755,31433,0,0,1169,69241,0,0,400,9424,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,91:3:0 0,12,139:4:0 +X 3140 . C <*> 0 . DP=21;I16=9,11,0,0,790,33238,0,0,1169,69241,0,0,402,9446,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,102:3:0 0,12,145:4:0 +X 3141 . C <*> 0 . DP=21;I16=9,11,0,0,819,35401,0,0,1169,69241,0,0,404,9480,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,101:3:0 0,12,150:4:0 +X 3142 . A <*> 0 . DP=21;I16=9,11,0,0,822,35744,0,0,1169,69241,0,0,405,9477,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,107:3:0 0,12,155:4:0 +X 3143 . G <*> 0 . DP=22;I16=10,11,0,0,846,36468,0,0,1198,70082,0,0,406,9488,0,0;QS=3,0;MQSB=0.99938;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,104:3:0 0,12,151:4:0 +X 3144 . C <*> 0 . DP=23;I16=12,10,0,0,855,35905,0,0,1258,73682,0,0,409,9513,0,0;QS=3,0;MQSB=0.997828;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,104:3:0 0,15,165:5:0 +X 3145 . A <*> 0 . DP=23;I16=12,10,0,0,869,35937,0,0,1258,73682,0,0,414,9554,0,0;QS=3,0;MQSB=0.997828;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,106:3:0 0,15,174:5:0 +X 3146 . G <*> 0 . DP=23;I16=12,10,0,0,895,38345,0,0,1258,73682,0,0,419,9613,0,0;QS=3,0;MQSB=0.997828;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,105:3:0 0,15,179:5:0 +X 3147 . G <*> 0 . DP=24;I16=11,11,0,0,851,34815,0,0,1289,76441,0,0,419,9623,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,123:4:0 0,15,172:5:0 +X 3148 . T <*> 0 . DP=24;I16=12,11,0,0,795,30097,0,0,1318,77282,0,0,428,9682,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,107:4:0 0,15,149:5:0 +X 3149 . G <*> 0 . DP=24;I16=12,11,0,0,910,38142,0,0,1318,77282,0,0,433,9743,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,120:4:0 0,15,167:5:0 +X 3150 . A <*> 0 . DP=24;I16=12,11,0,0,854,33784,0,0,1318,77282,0,0,438,9822,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,129:4:0 0,15,167:5:0 +X 3151 . C <*> 0 . DP=24;I16=12,11,0,0,873,35315,0,0,1318,77282,0,0,442,9870,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,125:4:0 0,15,163:5:0 +X 3152 . C <*> 0 . DP=24;I16=12,11,0,0,857,34239,0,0,1318,77282,0,0,445,9889,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,123:4:0 0,15,155:5:0 +X 3153 . C <*> 0 . DP=24;I16=12,11,0,0,891,36711,0,0,1318,77282,0,0,448,9930,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,125:4:0 0,15,166:5:0 +X 3154 . T <*> 0 . DP=25;I16=13,11,0,0,938,38052,0,0,1378,80882,0,0,451,9993,0,0;QS=3,0;MQSB=0.998323;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,133:4:0 0,18,194:6:0 +X 3155 . G <*> 0 . DP=25;I16=13,11,0,0,953,39423,0,0,1378,80882,0,0,454,10030,0,0;QS=3,0;MQSB=0.998323;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,127:4:0 0,18,180:6:0 +X 3156 . G <*> 0 . DP=25;I16=13,11,0,0,946,38818,0,0,1378,80882,0,0,457,10093,0,0;QS=3,0;MQSB=0.998323;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,126:4:0 0,18,189:6:0 +X 3157 . A <*> 0 . DP=24;I16=12,12,0,0,896,33648,0,0,1378,80882,0,0,486,10806,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,130:4:0 0,18,193:6:0 +X 3158 . A <*> 0 . DP=24;I16=12,12,0,0,856,31670,0,0,1378,80882,0,0,490,10918,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,125:4:0 0,18,192:6:0 +X 3159 . T <*> 0 . DP=24;I16=11,12,0,0,864,32952,0,0,1349,80041,0,0,477,10749,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,134:4:0 0,18,194:6:0 +X 3160 . T <*> 0 . DP=24;I16=12,12,0,0,907,34719,0,0,1378,80882,0,0,494,11018,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,134:4:0 0,18,193:6:0 +X 3161 . C <*> 0 . DP=24;I16=12,12,0,0,880,33336,0,0,1378,80882,0,0,494,11006,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,123:4:0 0,18,196:6:0 +X 3162 . C <*> 0 . DP=24;I16=12,12,0,0,916,35764,0,0,1378,80882,0,0,494,11018,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,127:4:0 0,18,188:6:0 +X 3163 . T A,<*> 0 . DP=24;I16=11,12,1,0,895,35099,13,169,1349,80041,29,841,473,10603,20,400;QS=2.97436,0.025641,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,28,255,39,255,255:14:1 0,12,137,12,137,137:4:0 0,18,200,18,200,200:6:0 +X 3164 . G <*> 0 . DP=24;I16=12,11,0,0,887,34437,0,0,1349,80041,0,0,467,10385,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,106:3:0 0,18,188:6:0 +X 3165 . T <*> 0 . DP=24;I16=12,12,0,0,880,32654,0,0,1378,80882,0,0,490,10990,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,133:4:0 0,18,189:6:0 +X 3166 . C <*> 0 . DP=24;I16=12,11,0,0,871,33389,0,0,1349,80041,0,0,463,10369,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,111:3:0 0,18,193:6:0 +X 3167 . C <*> 0 . DP=23;I16=12,11,0,0,879,34199,0,0,1318,77282,0,0,487,11021,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,131:4:0 0,18,189:6:0 +X 3168 . A <*> 0 . DP=23;I16=12,11,0,0,874,33294,0,0,1318,77282,0,0,486,11070,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,125:4:0 0,18,192:6:0 +X 3169 . T <*> 0 . DP=23;I16=11,11,0,0,824,31124,0,0,1289,76441,0,0,458,10416,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,128:4:0 0,18,187:6:0 +X 3170 . C <*> 0 . DP=23;I16=11,11,0,0,877,35167,0,0,1289,76441,0,0,453,10307,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,129:4:0 0,18,201:6:0 +X 3171 . T <*> 0 . DP=23;I16=11,11,0,0,843,32615,0,0,1289,76441,0,0,448,10216,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,127:4:0 0,18,201:6:0 +X 3172 . G <*> 0 . DP=23;I16=12,11,0,0,813,29605,0,0,1318,77282,0,0,468,10768,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,120:4:0 0,18,176:6:0 +X 3173 . G <*> 0 . DP=23;I16=11,11,0,0,801,29659,0,0,1289,76441,0,0,436,9988,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,126:4:0 0,18,174:6:0 +X 3174 . C <*> 0 . DP=24;I16=13,11,0,0,938,36926,0,0,1378,80882,0,0,454,10476,0,0;QS=3,0;MQSB=0.998323;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,127:4:0 0,18,194:6:0 +X 3175 . A <*> 0 . DP=25;I16=13,11,0,0,914,35230,0,0,1409,83641,0,0,422,9684,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,127:4:0 0,21,209:7:0 +X 3176 . G <*> 0 . DP=24;I16=14,10,0,0,909,34913,0,0,1378,80882,0,0,442,10164,0,0;QS=3,0;MQSB=0.993166;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,97:3:0 0,21,205:7:0 +X 3177 . G <*> 0 . DP=23;I16=14,9,0,0,793,28159,0,0,1318,77282,0,0,438,10040,0,0;QS=3,0;MQSB=0.987676;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,93:3:0 0,21,195:7:0 +X 3178 . T <*> 0 . DP=23;I16=13,9,0,0,754,26290,0,0,1289,76441,0,0,408,9262,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,96:3:0 0,21,173:7:0 +X 3179 . G <*> 0 . DP=23;I16=13,9,0,0,802,29686,0,0,1289,76441,0,0,403,9131,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,97:3:0 0,21,188:7:0 +X 3180 . G <*> 0 . DP=22;I16=12,9,0,0,701,24107,0,0,1229,72841,0,0,398,8970,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,92:3:0 0,21,175:7:0 +X 3181 . G <*> 0 . DP=22;I16=13,9,0,0,795,29503,0,0,1258,73682,0,0,418,9452,0,0;QS=3,0;MQSB=0.991121;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,99:3:0 0,21,193:7:0 +X 3182 . C <*> 0 . DP=22;I16=12,9,0,0,772,28878,0,0,1198,70082,0,0,396,9038,0,0;QS=3,0;MQSB=0.994334;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,99:3:0 0,21,184:7:0 +X 3183 . A <*> 0 . DP=22;I16=12,9,0,0,766,28304,0,0,1229,72841,0,0,382,8546,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,106:3:0 0,21,193:7:0 +X 3184 . T <*> 0 . DP=21;I16=12,8,0,0,721,26533,0,0,1169,69241,0,0,377,8409,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,9,106:3:0 0,21,196:7:0 +X 3185 . T <*> 0 . DP=20;I16=13,7,0,0,740,27660,0,0,1138,66482,0,0,397,8865,0,0;QS=3,0;MQSB=0.972138;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,103:3:0 0,18,174:6:0 +X 3186 . G <*> 0 . DP=20;I16=13,7,0,0,741,28311,0,0,1138,66482,0,0,391,8665,0,0;QS=3,0;MQSB=0.972138;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,103:3:0 0,18,169:6:0 +X 3187 . A <*> 0 . DP=20;I16=13,7,0,0,693,24927,0,0,1138,66482,0,0,385,8485,0,0;QS=3,0;MQSB=0.972138;MQ0F=0 PL:DP:DV 0,33,247:11:0 0,9,102:3:0 0,18,171:6:0 +X 3188 . A <*> 0 . DP=20;I16=13,7,0,0,704,25746,0,0,1138,66482,0,0,379,8325,0,0;QS=3,0;MQSB=0.972138;MQ0F=0 PL:DP:DV 0,33,249:11:0 0,9,100:3:0 0,18,174:6:0 +X 3189 . A <*> 0 . DP=21;I16=13,8,0,0,763,28171,0,0,1198,70082,0,0,373,8185,0,0;QS=3,0;MQSB=0.983744;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,125:4:0 0,18,174:6:0 +X 3190 . C <*> 0 . DP=20;I16=11,8,0,0,675,24915,0,0,1109,65641,0,0,344,7440,0,0;QS=3,0;MQSB=0.902014;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,123:4:0 0,15,148:5:0 +X 3191 . T <*> 0 . DP=21;I16=11,9,0,0,773,30203,0,0,1169,69241,0,0,340,7340,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,130:4:0 0,15,171:5:0 +X 3192 . G <*> 0 . DP=21;I16=12,9,0,0,751,27785,0,0,1198,70082,0,0,362,7886,0,0;QS=3,0;MQSB=0.994334;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,125:4:0 0,15,152:5:0 +X 3193 . G <*> 0 . DP=21;I16=12,9,0,0,756,27614,0,0,1198,70082,0,0,359,7829,0,0;QS=3,0;MQSB=0.994334;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,121:4:0 0,15,148:5:0 +X 3194 . T C,<*> 0 . DP=21;I16=10,10,1,0,730,26992,18,324,1169,69241,29,841,332,7168,25,625;QS=2.95652,0.0434783,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.99938;BQB=1;MQ0F=0 PL:DP:DV 0,18,255,33,255,255:12:1 0,9,98,9,98,98:3:0 0,18,178,18,178,178:6:0 +X 3195 . T <*> 0 . DP=21;I16=11,10,0,0,776,29184,0,0,1198,70082,0,0,356,7778,0,0;QS=3,0;MQSB=0.99938;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,95:3:0 0,18,189:6:0 +X 3196 . T <*> 0 . DP=21;I16=10,10,0,0,722,26472,0,0,1169,69241,0,0,329,7111,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,91:3:0 0,18,186:6:0 +X 3197 . A <*> 0 . DP=22;I16=12,9,0,0,715,24911,0,0,1229,72841,0,0,352,7718,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,103:3:0 0,18,179:6:0 +X 3198 . A <*> 0 . DP=21;I16=12,8,0,0,745,28155,0,0,1169,69241,0,0,345,7675,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,105:3:0 0,18,198:6:0 +X 3199 . A <*> 0 . DP=21;I16=11,9,0,0,736,27514,0,0,1200,72000,0,0,326,7080,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,105:3:0 0,18,196:6:0 +X 3200 . A <*> 0 . DP=20;I16=11,9,0,0,735,27533,0,0,1169,69241,0,0,350,7660,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,108:3:0 0,18,195:6:0 +X 3201 . A <*> 0 . DP=20;I16=11,8,0,0,706,26814,0,0,1109,65641,0,0,338,7486,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,9,107:3:0 0,18,198:6:0 +X 3202 . T <*> 0 . DP=20;I16=10,9,0,0,692,25620,0,0,1140,68400,0,0,321,6907,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,9,109:3:0 0,18,187:6:0 +X 3203 . G A,<*> 0 . DP=19;I16=9,9,1,0,644,23760,19,361,1080,64800,29,841,320,6872,25,625;QS=2.94823,0.0517711,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.934728;BQB=1;MQ0F=0 PL:DP:DV 0,14,239,30,242,248:11:1 0,9,105,9,105,105:3:0 0,15,160,15,160,160:5:0 +X 3204 . T <*> 0 . DP=19;I16=9,8,0,0,619,22955,0,0,1020,61200,0,0,306,6686,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,234:9:0 0,9,101:3:0 0,15,169:5:0 +X 3205 . C <*> 0 . DP=19;I16=9,9,0,0,672,25340,0,0,1080,64800,0,0,318,6856,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,99:3:0 0,15,157:5:0 +X 3206 . A <*> 0 . DP=19;I16=10,9,0,0,661,23623,0,0,1109,65641,0,0,342,7500,0,0;QS=3,0;MQSB=0.934728;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,91:3:0 0,15,165:5:0 +X 3207 . C <*> 0 . DP=19;I16=9,9,0,0,642,23618,0,0,1080,64800,0,0,316,6912,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,90:3:0 0,15,158:5:0 +X 3208 . A <*> 0 . DP=18;I16=10,8,0,0,619,22023,0,0,1049,62041,0,0,341,7591,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,33,247:11:0 0,9,95:3:0 0,12,142:4:0 +X 3209 . C <*> 0 . DP=19;I16=11,8,0,0,681,24747,0,0,1109,65641,0,0,340,7612,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,106:3:0 0,12,134:4:0 +X 3210 . C <*> 0 . DP=18;I16=11,7,0,0,664,24900,0,0,1049,62041,0,0,340,7602,0,0;QS=3,0;MQSB=0.951002;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,101:3:0 0,12,141:4:0 +X 3211 . A <*> 0 . DP=17;I16=11,6,0,0,645,24627,0,0,989,58441,0,0,341,7611,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,9,106:3:0 0,12,140:4:0 +X 3212 . T <*> 0 . DP=17;I16=10,6,0,0,575,21295,0,0,960,57600,0,0,316,6964,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,222:9:0 0,9,100:3:0 0,12,144:4:0 +X 3213 . A <*> 0 . DP=17;I16=10,6,0,0,597,22631,0,0,960,57600,0,0,316,6962,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,9,117:3:0 0,12,138:4:0 +X 3214 . G <*> 0 . DP=17;I16=11,6,0,0,615,23103,0,0,989,58441,0,0,341,7605,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,9,110:3:0 0,12,134:4:0 +X 3215 . G <*> 0 . DP=17;I16=11,6,0,0,591,21523,0,0,989,58441,0,0,340,7592,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,30,241:10:0 0,9,93:3:0 0,12,128:4:0 +X 3216 . C <*> 0 . DP=17;I16=11,6,0,0,623,23303,0,0,989,58441,0,0,339,7597,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,30,242:10:0 0,9,94:3:0 0,12,138:4:0 +X 3217 . C <*> 0 . DP=17;I16=11,6,0,0,570,19896,0,0,989,58441,0,0,337,7569,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,30,236:10:0 0,9,84:3:0 0,12,123:4:0 +X 3218 . G C,<*> 0 . DP=18;I16=10,7,1,0,547,18185,29,841,1020,61200,29,841,310,6932,24,576;QS=2.91667,0.0833333,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.951002;BQB=1;MQ0F=0 PL:DP:DV 0,4,202,30,205,221:11:1 0,9,96,9,96,96:3:0 0,12,112,12,112,112:4:0 +X 3219 . G A,<*> 0 . DP=18;I16=10,7,1,0,606,22158,19,361,1020,61200,29,841,308,6888,23,529;QS=2.94837,0.0516304,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.951002;BQB=1;MQ0F=0 PL:DP:DV 0,14,234,30,237,243:11:1 0,9,107,9,107,107:3:0 0,12,126,12,126,126:4:0 +X 3220 . G <*> 0 . DP=18;I16=11,7,0,0,631,22827,0,0,1049,62041,0,0,326,7248,0,0;QS=3,0;MQSB=0.951002;MQ0F=0 PL:DP:DV 0,33,252:11:0 0,9,112:3:0 0,12,126:4:0 +X 3221 . C <*> 0 . DP=17;I16=9,7,0,0,598,22586,0,0,960,57600,0,0,301,6659,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,9,103:3:0 0,12,139:4:0 +X 3222 . A <*> 0 . DP=17;I16=10,7,0,0,623,23037,0,0,989,58441,0,0,318,6972,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,100:3:0 0,12,133:4:0 +X 3223 . C <*> 0 . DP=17;I16=10,7,0,0,611,22603,0,0,989,58441,0,0,312,6764,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,96:3:0 0,12,132:4:0 +X 3224 . A <*> 0 . DP=16;I16=10,6,0,0,609,23381,0,0,929,54841,0,0,307,6575,0,0;QS=3,0;MQSB=0.948436;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,9,97:3:0 0,12,141:4:0 +X 3225 . G <*> 0 . DP=17;I16=11,6,0,0,604,22692,0,0,989,58441,0,0,302,6404,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,27,247:9:0 0,12,108:4:0 0,12,134:4:0 +X 3226 . T <*> 0 . DP=18;I16=11,6,0,0,582,20466,0,0,1020,61200,0,0,282,5996,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,224:9:0 0,12,112:4:0 0,12,131:4:0 +X 3227 . G <*> 0 . DP=18;I16=12,5,0,0,618,23008,0,0,989,58441,0,0,270,5496,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,91:3:0 0,12,125:4:0 +X 3228 . G <*> 0 . DP=18;I16=11,6,0,0,611,22581,0,0,1020,61200,0,0,278,5816,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,248:9:0 0,12,118:4:0 0,12,121:4:0 +X 3229 . C <*> 0 . DP=19;I16=12,7,0,0,686,25394,0,0,1109,65641,0,0,289,5925,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,118:4:0 0,12,126:4:0 +X 3230 . T <*> 0 . DP=19;I16=12,6,0,0,669,25441,0,0,1049,62041,0,0,261,5187,0,0;QS=3,0;MQSB=0.961295;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,107:3:0 0,12,139:4:0 +X 3231 . C <*> 0 . DP=19;I16=12,7,0,0,682,25046,0,0,1109,65641,0,0,283,5725,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,112:4:0 0,12,128:4:0 +X 3232 . A <*> 0 . DP=19;I16=11,7,0,0,597,20779,0,0,1080,64800,0,0,270,5564,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,229:10:0 0,12,117:4:0 0,12,132:4:0 +X 3233 . C <*> 0 . DP=19;I16=12,7,0,0,573,18239,0,0,1109,65641,0,0,277,5629,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,33,238:11:0 0,12,91:4:0 0,12,110:4:0 +X 3234 . G T,<*> 0 . DP=19;I16=10,6,1,0,511,17305,22,484,960,57600,29,841,233,4849,8,64;QS=2.93855,0.0614525,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.955563;BQB=1;MQ0F=0 PL:DP:DV 0,11,222,30,225,234:11:1 0,6,63,6,63,63:2:0 0,12,100,12,100,100:4:0 +X 3235 . C <*> 0 . DP=18;I16=12,6,0,0,625,22649,0,0,1049,62041,0,0,274,5582,0,0;QS=3,0;MQSB=0.961295;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,12,119:4:0 0,12,123:4:0 +X 3236 . C <*> 0 . DP=18;I16=12,6,0,0,668,25124,0,0,1049,62041,0,0,273,5567,0,0;QS=3,0;MQSB=0.961295;MQ0F=0 PL:DP:DV 0,30,244:10:0 0,12,137:4:0 0,12,134:4:0 +X 3237 . T <*> 0 . DP=17;I16=11,6,0,0,589,21235,0,0,989,58441,0,0,273,5573,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,27,230:9:0 0,12,102:4:0 0,12,136:4:0 +X 3238 . G <*> 0 . DP=17;I16=11,6,0,0,609,22539,0,0,989,58441,0,0,273,5599,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,27,243:9:0 0,12,104:4:0 0,12,129:4:0 +X 3239 . T <*> 0 . DP=17;I16=11,6,0,0,574,20204,0,0,989,58441,0,0,273,5645,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,27,220:9:0 0,12,107:4:0 0,12,131:4:0 +X 3240 . A <*> 0 . DP=19;I16=12,7,0,0,624,21552,0,0,1109,65641,0,0,273,5711,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,33,248:11:0 0,12,101:4:0 0,12,132:4:0 +X 3241 . A <*> 0 . DP=19;I16=11,6,0,0,619,23121,0,0,1020,61200,0,0,249,5173,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,9,96:3:0 0,12,143:4:0 +X 3242 . T <*> 0 . DP=19;I16=12,7,0,0,655,23279,0,0,1140,68400,0,0,277,5911,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,12,104:4:0 0,15,152:5:0 +X 3243 . C <*> 0 . DP=19;I16=12,7,0,0,682,25216,0,0,1140,68400,0,0,281,6047,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,111:4:0 0,15,148:5:0 +X 3244 . C <*> 0 . DP=18;I16=11,6,0,0,587,21119,0,0,1020,61200,0,0,281,6139,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,12,116:4:0 0,15,142:5:0 +X 3245 . C <*> 0 . DP=17;I16=10,7,0,0,631,23851,0,0,1020,61200,0,0,290,6282,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,12,126:4:0 0,12,131:4:0 +X 3246 . A <*> 0 . DP=17;I16=10,7,0,0,646,24716,0,0,1020,61200,0,0,295,6427,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,12,129:4:0 0,12,139:4:0 +X 3247 . G <*> 0 . DP=17;I16=10,7,0,0,606,22554,0,0,1020,61200,0,0,300,6590,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,12,92:4:0 0,12,133:4:0 +X 3248 . C <*> 0 . DP=16;I16=10,6,0,0,603,23115,0,0,960,57600,0,0,306,6770,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,9,99:3:0 0,12,132:4:0 +X 3249 . C <*> 0 . DP=16;I16=10,6,0,0,587,21913,0,0,960,57600,0,0,311,6917,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,246:9:0 0,9,99:3:0 0,12,133:4:0 +X 3250 . C <*> 0 . DP=16;I16=10,6,0,0,616,24080,0,0,960,57600,0,0,316,7082,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,9,95:3:0 0,12,137:4:0 +X 3251 . T <*> 0 . DP=16;I16=10,6,0,0,585,22193,0,0,960,57600,0,0,319,7165,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,9,104:3:0 0,12,135:4:0 +X 3252 . T <*> 0 . DP=16;I16=10,6,0,0,553,19781,0,0,960,57600,0,0,321,7215,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,9,84:3:0 0,12,126:4:0 +X 3253 . T <*> 0 . DP=16;I16=10,6,0,0,589,21933,0,0,960,57600,0,0,323,7281,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,245:9:0 0,9,102:3:0 0,12,132:4:0 +X 3254 . G <*> 0 . DP=17;I16=10,7,0,0,631,23737,0,0,1020,61200,0,0,325,7363,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,9,100:3:0 0,15,154:5:0 +X 3255 . G <*> 0 . DP=16;I16=9,7,0,0,554,20088,0,0,960,57600,0,0,328,7410,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,243:9:0 0,9,93:3:0 0,12,120:4:0 +X 3256 . G <*> 0 . DP=16;I16=8,7,0,0,571,21985,0,0,900,54000,0,0,306,6846,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,6,62:2:0 0,12,142:4:0 +X 3257 . A <*> 0 . DP=16;I16=9,7,0,0,585,21881,0,0,960,57600,0,0,334,7546,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,243:9:0 0,9,94:3:0 0,12,144:4:0 +X 3258 . G <*> 0 . DP=17;I16=9,8,0,0,647,25407,0,0,1020,61200,0,0,337,7635,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,81:3:0 0,12,146:4:0 +X 3259 . G <*> 0 . DP=17;I16=9,8,0,0,605,22237,0,0,1020,61200,0,0,341,7739,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,79:3:0 0,12,139:4:0 +X 3260 . C <*> 0 . DP=17;I16=9,7,0,0,616,23908,0,0,960,57600,0,0,319,7183,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,6,64:2:0 0,12,133:4:0 +X 3261 . C <*> 0 . DP=18;I16=9,9,0,0,655,24475,0,0,1080,64800,0,0,347,7891,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,90:3:0 0,12,138:4:0 +X 3262 . A <*> 0 . DP=19;I16=10,9,0,0,712,27036,0,0,1140,68400,0,0,351,7989,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,123:4:0 0,12,148:4:0 +X 3263 . G <*> 0 . DP=19;I16=10,9,0,0,715,27317,0,0,1140,68400,0,0,356,8104,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,116:4:0 0,12,146:4:0 +X 3264 . G <*> 0 . DP=19;I16=10,9,0,0,676,24734,0,0,1140,68400,0,0,361,8237,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,93:4:0 0,12,143:4:0 +X 3265 . G <*> 0 . DP=19;I16=10,9,0,0,701,26199,0,0,1140,68400,0,0,365,8339,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,109:4:0 0,12,137:4:0 +X 3266 . T <*> 0 . DP=19;I16=9,9,0,0,597,20769,0,0,1080,64800,0,0,357,8229,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,82:4:0 0,9,113:3:0 +X 3267 . G <*> 0 . DP=19;I16=10,9,0,0,659,24285,0,0,1140,68400,0,0,367,8299,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,76:4:0 0,12,133:4:0 +X 3268 . G <*> 0 . DP=19;I16=10,9,0,0,668,24306,0,0,1140,68400,0,0,367,8255,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,92:4:0 0,12,142:4:0 +X 3269 . G <*> 0 . DP=19;I16=10,9,0,0,714,27122,0,0,1140,68400,0,0,367,8227,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,115:4:0 0,12,137:4:0 +X 3270 . T <*> 0 . DP=20;I16=10,9,0,0,606,20364,0,0,1140,68400,0,0,361,8141,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,251:11:0 0,12,83:4:0 0,12,136:4:0 +X 3271 . G <*> 0 . DP=19;I16=10,9,0,0,709,26993,0,0,1140,68400,0,0,362,8108,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,100:4:0 0,12,143:4:0 +X 3272 . G <*> 0 . DP=19;I16=10,9,0,0,672,24398,0,0,1140,68400,0,0,363,8093,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,97:4:0 0,12,140:4:0 +X 3273 . A <*> 0 . DP=20;I16=10,10,0,0,735,27355,0,0,1200,72000,0,0,363,8047,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,153:5:0 0,12,147:4:0 +X 3274 . T <*> 0 . DP=19;I16=9,10,0,0,699,26089,0,0,1140,68400,0,0,365,8021,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,142:5:0 0,12,149:4:0 +X 3275 . C <*> 0 . DP=19;I16=9,10,0,0,727,28197,0,0,1140,68400,0,0,367,8015,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,137:5:0 0,12,139:4:0 +X 3276 . A <*> 0 . DP=19;I16=9,10,0,0,681,25123,0,0,1140,68400,0,0,369,8029,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,15,150:5:0 0,12,141:4:0 +X 3277 . C <*> 0 . DP=19;I16=9,10,0,0,733,28485,0,0,1140,68400,0,0,371,8063,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,153:5:0 0,12,146:4:0 +X 3278 . T <*> 0 . DP=19;I16=9,10,0,0,737,28901,0,0,1140,68400,0,0,373,8117,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,168:5:0 0,12,153:4:0 +X 3279 . T <*> 0 . DP=19;I16=9,10,0,0,714,27132,0,0,1140,68400,0,0,375,8191,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,148:5:0 0,12,150:4:0 +X 3280 . G <*> 0 . DP=20;I16=9,11,0,0,758,29178,0,0,1200,72000,0,0,376,8234,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,143:5:0 0,12,146:4:0 +X 3281 . A <*> 0 . DP=21;I16=10,11,0,0,822,32654,0,0,1260,75600,0,0,378,8296,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,179:6:0 0,12,157:4:0 +X 3282 . G <*> 0 . DP=21;I16=10,11,0,0,815,32059,0,0,1260,75600,0,0,381,8379,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,173:6:0 0,12,150:4:0 +X 3283 . G <*> 0 . DP=21;I16=10,11,0,0,790,30110,0,0,1260,75600,0,0,384,8484,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,161:6:0 0,12,146:4:0 +X 3284 . T <*> 0 . DP=21;I16=10,11,0,0,748,27628,0,0,1260,75600,0,0,385,8511,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,155:6:0 0,12,146:4:0 +X 3285 . C <*> 0 . DP=21;I16=10,11,0,0,776,29442,0,0,1260,75600,0,0,386,8560,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,169:6:0 0,12,143:4:0 +X 3286 . A <*> 0 . DP=21;I16=10,11,0,0,826,32732,0,0,1260,75600,0,0,387,8631,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,187:6:0 0,12,153:4:0 +X 3287 . G <*> 0 . DP=21;I16=10,11,0,0,804,31448,0,0,1260,75600,0,0,387,8673,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,164:6:0 0,12,150:4:0 +X 3288 . G <*> 0 . DP=22;I16=10,11,0,0,754,27862,0,0,1260,75600,0,0,379,8635,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,141:5:0 0,15,164:5:0 +X 3289 . A <*> 0 . DP=24;I16=13,11,0,0,897,34439,0,0,1440,86400,0,0,386,8714,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,166:6:0 0,15,178:5:0 +X 3290 . G <*> 0 . DP=23;I16=12,10,0,0,832,31964,0,0,1320,79200,0,0,380,8684,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,112:4:0 0,15,168:5:0 +X 3291 . T <*> 0 . DP=22;I16=11,9,0,0,707,25481,0,0,1200,72000,0,0,358,8112,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,95:3:0 0,15,168:5:0 +X 3292 . T <*> 0 . DP=22;I16=13,9,0,0,783,28439,0,0,1320,79200,0,0,397,8929,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,127:5:0 0,15,164:5:0 +X 3293 . C <*> 0 . DP=22;I16=13,9,0,0,852,33430,0,0,1320,79200,0,0,400,8992,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,136:5:0 0,15,170:5:0 +X 3294 . A <*> 0 . DP=22;I16=13,9,0,0,818,30684,0,0,1320,79200,0,0,403,9077,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,145:5:0 0,15,162:5:0 +X 3295 . A <*> 0 . DP=22;I16=14,8,0,0,820,31004,0,0,1320,79200,0,0,407,9183,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,140:5:0 0,12,143:4:0 +X 3296 . G <*> 0 . DP=22;I16=14,8,0,0,837,32209,0,0,1320,79200,0,0,411,9259,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,133:5:0 0,12,140:4:0 +X 3297 . A <*> 0 . DP=22;I16=14,8,0,0,787,28771,0,0,1320,79200,0,0,415,9355,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,134:5:0 0,12,140:4:0 +X 3298 . C <*> 0 . DP=22;I16=13,9,0,0,826,31506,0,0,1320,79200,0,0,420,9470,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,113:4:0 0,12,135:4:0 +X 3299 . C <*> 0 . DP=22;I16=13,9,0,0,857,33829,0,0,1320,79200,0,0,425,9553,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,117:4:0 0,12,140:4:0 +X 3300 . A <*> 0 . DP=22;I16=13,9,0,0,861,33855,0,0,1320,79200,0,0,430,9654,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,134:4:0 0,12,144:4:0 +X 3301 . G <*> 0 . DP=22;I16=13,9,0,0,869,34495,0,0,1320,79200,0,0,433,9675,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,131:4:0 0,12,141:4:0 +X 3302 . C <*> 0 . DP=23;I16=14,9,0,0,863,32885,0,0,1380,82800,0,0,436,9718,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,115:4:0 0,15,155:5:0 +X 3303 . C <*> 0 . DP=23;I16=14,9,0,0,887,34451,0,0,1380,82800,0,0,440,9784,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,125:4:0 0,15,153:5:0 +X 3304 . T <*> 0 . DP=23;I16=14,9,0,0,886,34388,0,0,1380,82800,0,0,443,9825,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,134:4:0 0,15,167:5:0 +X 3305 . G <*> 0 . DP=23;I16=14,9,0,0,878,33846,0,0,1380,82800,0,0,446,9892,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,119:4:0 0,15,151:5:0 +X 3306 . G <*> 0 . DP=23;I16=14,9,0,0,886,34386,0,0,1380,82800,0,0,448,9934,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,127:4:0 0,15,150:5:0 +X 3307 . C <*> 0 . DP=23;I16=14,8,0,0,812,30814,0,0,1320,79200,0,0,428,9508,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,116:4:0 0,15,153:5:0 +X 3308 . C <*> 0 . DP=23;I16=14,9,0,0,835,31367,0,0,1380,82800,0,0,450,9986,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,118:4:0 0,15,151:5:0 +X 3309 . A <*> 0 . DP=23;I16=14,9,0,0,875,33541,0,0,1380,82800,0,0,451,9995,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,128:4:0 0,15,162:5:0 +X 3310 . A <*> 0 . DP=24;I16=15,9,0,0,882,32950,0,0,1440,86400,0,0,453,10027,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,152:5:0 0,15,164:5:0 +X 3311 . C <*> 0 . DP=24;I16=15,9,0,0,913,35161,0,0,1440,86400,0,0,456,10084,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,145:5:0 0,15,157:5:0 +X 3312 . A <*> 0 . DP=26;I16=16,9,0,0,950,36336,0,0,1500,90000,0,0,459,10167,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,153:5:0 0,15,160:5:0 +X 3313 . T <*> 0 . DP=26;I16=16,10,0,0,987,37617,0,0,1560,93600,0,0,488,10902,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,180:6:0 0,15,161:5:0 +X 3314 . G <*> 0 . DP=26;I16=16,10,0,0,1007,39401,0,0,1560,93600,0,0,491,10989,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,171:6:0 0,15,161:5:0 +X 3315 . G <*> 0 . DP=26;I16=15,10,0,0,945,36073,0,0,1500,90000,0,0,484,10866,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,172:6:0 0,15,159:5:0 +X 3316 . T <*> 0 . DP=26;I16=15,10,0,0,853,29881,0,0,1500,90000,0,0,464,10216,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,157:6:0 0,12,122:4:0 +X 3317 . G <*> 0 . DP=27;I16=16,11,0,0,997,37431,0,0,1620,97200,0,0,488,10806,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,164:6:0 0,18,167:6:0 +X 3318 . A <*> 0 . DP=26;I16=15,10,0,0,904,33212,0,0,1500,90000,0,0,481,10699,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,155:5:0 0,18,185:6:0 +X 3319 . A <*> 0 . DP=25;I16=15,10,0,0,912,34090,0,0,1500,90000,0,0,482,10682,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,139:5:0 0,18,188:6:0 +X 3320 . A <*> 0 . DP=25;I16=15,10,0,0,888,32722,0,0,1500,90000,0,0,483,10691,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,133:5:0 0,18,178:6:0 +X 3321 . C <*> 0 . DP=25;I16=14,10,0,0,900,34142,0,0,1440,86400,0,0,471,10531,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,157:5:0 0,18,186:6:0 +X 3322 . C <*> 0 . DP=25;I16=15,10,0,0,980,38582,0,0,1500,90000,0,0,483,10683,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,164:5:0 0,18,198:6:0 +X 3323 . C <*> 0 . DP=25;I16=15,10,0,0,922,34948,0,0,1500,90000,0,0,483,10715,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,146:5:0 0,18,201:6:0 +X 3324 . C <*> 0 . DP=25;I16=15,10,0,0,869,31271,0,0,1500,90000,0,0,482,10720,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,142:5:0 0,18,186:6:0 +X 3325 . G <*> 0 . DP=25;I16=15,10,0,0,827,28293,0,0,1500,90000,0,0,481,10747,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,134:5:0 0,18,163:6:0 +X 3326 . T <*> 0 . DP=24;I16=13,10,0,0,842,31362,0,0,1380,82800,0,0,464,10506,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,150:5:0 0,18,186:6:0 +X 3327 . C <*> 0 . DP=24;I16=14,10,0,0,938,37076,0,0,1440,86400,0,0,481,10863,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,154:5:0 0,18,190:6:0 +X 3328 . T <*> 0 . DP=25;I16=15,10,0,0,959,37033,0,0,1500,90000,0,0,480,10900,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,163:5:0 0,21,213:7:0 +X 3329 . A <*> 0 . DP=24;I16=15,9,0,0,888,33082,0,0,1440,86400,0,0,481,10955,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,149:5:0 0,21,207:7:0 +X 3330 . C <*> 0 . DP=25;I16=16,9,0,0,954,37064,0,0,1500,90000,0,0,481,10979,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,168:5:0 0,21,203:7:0 +X 3331 . T <*> 0 . DP=25;I16=16,9,0,0,960,37332,0,0,1500,90000,0,0,482,11024,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,165:5:0 0,21,224:7:0 +X 3332 . A <*> 0 . DP=25;I16=16,9,0,0,933,35065,0,0,1500,90000,0,0,483,11091,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,165:5:0 0,21,211:7:0 +X 3333 . A <*> 0 . DP=26;I16=16,10,0,0,976,37344,0,0,1560,93600,0,0,483,11131,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,166:5:0 0,24,241:8:0 +X 3334 . A <*> 0 . DP=25;I16=15,10,0,0,972,38210,0,0,1500,90000,0,0,485,11195,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,168:5:0 0,24,241:8:0 +X 3335 . A <*> 0 . DP=25;I16=15,10,0,0,970,38200,0,0,1500,90000,0,0,486,11232,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,170:5:0 0,24,239:8:0 +X 3336 . A <*> 0 . DP=25;I16=15,10,0,0,929,35277,0,0,1500,90000,0,0,485,11191,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,166:5:0 0,24,232:8:0 +X 3337 . T <*> 0 . DP=25;I16=15,10,0,0,902,32856,0,0,1500,90000,0,0,484,11172,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,157:5:0 0,24,224:8:0 +X 3338 . A <*> 0 . DP=25;I16=15,10,0,0,892,32056,0,0,1500,90000,0,0,481,11075,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,153:5:0 0,24,214:8:0 +X 3339 . C <*> 0 . DP=25;I16=15,10,0,0,964,37444,0,0,1500,90000,0,0,478,11000,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,167:5:0 0,24,232:8:0 +X 3340 . A <*> 0 . DP=23;I16=14,9,0,0,890,34616,0,0,1380,82800,0,0,477,10945,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,173:5:0 0,24,233:8:0 +X 3341 . A <*> 0 . DP=23;I16=14,9,0,0,885,34459,0,0,1380,82800,0,0,476,10908,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,167:5:0 0,24,238:8:0 +X 3342 . A <*> 0 . DP=23;I16=14,9,0,0,862,33262,0,0,1380,82800,0,0,475,10889,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,170:5:0 0,24,240:8:0 +X 3343 . A <*> 0 . DP=22;I16=13,9,0,0,866,34280,0,0,1320,79200,0,0,474,10836,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,173:5:0 0,21,231:7:0 +X 3344 . A <*> 0 . DP=22;I16=13,9,0,0,859,33731,0,0,1320,79200,0,0,473,10797,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,173:5:0 0,21,226:7:0 +X 3345 . T <*> 0 . DP=22;I16=13,9,0,0,822,31100,0,0,1320,79200,0,0,472,10772,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,254:10:0 0,15,159:5:0 0,21,220:7:0 +X 3346 . T <*> 0 . DP=22;I16=13,9,0,0,847,32679,0,0,1320,79200,0,0,470,10712,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,168:5:0 0,21,221:7:0 +X 3347 . A <*> 0 . DP=23;I16=14,9,0,0,888,34650,0,0,1380,82800,0,0,468,10668,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,185:6:0 0,21,227:7:0 +X 3348 . G <*> 0 . DP=23;I16=14,9,0,0,873,33609,0,0,1380,82800,0,0,467,10641,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,171:6:0 0,21,219:7:0 +X 3349 . C <*> 0 . DP=24;I16=14,9,0,0,815,29785,0,0,1380,82800,0,0,465,10583,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,166:6:0 0,21,205:7:0 +X 3350 . C <*> 0 . DP=24;I16=14,10,0,0,939,37249,0,0,1440,86400,0,0,464,10546,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,209:7:0 0,21,220:7:0 +X 3351 . T <*> 0 . DP=24;I16=14,10,0,0,943,37255,0,0,1440,86400,0,0,463,10531,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,210:7:0 0,21,228:7:0 +X 3352 . G <*> 0 . DP=24;I16=14,10,0,0,887,33267,0,0,1440,86400,0,0,462,10538,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,192:7:0 0,21,214:7:0 +X 3353 . G <*> 0 . DP=24;I16=14,10,0,0,864,32092,0,0,1440,86400,0,0,461,10567,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,190:7:0 0,21,214:7:0 +X 3354 . C <*> 0 . DP=24;I16=14,10,0,0,848,30714,0,0,1440,86400,0,0,459,10567,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,178:7:0 0,21,209:7:0 +X 3355 . G <*> 0 . DP=23;I16=14,9,0,0,738,24386,0,0,1380,82800,0,0,457,10537,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,232:10:0 0,21,170:7:0 0,18,166:6:0 +X 3356 . T <*> 0 . DP=23;I16=14,9,0,0,847,31689,0,0,1380,82800,0,0,454,10476,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,191:7:0 0,18,195:6:0 +X 3357 . G <*> 0 . DP=23;I16=14,9,0,0,863,32919,0,0,1380,82800,0,0,449,10335,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,193:7:0 0,18,192:6:0 +X 3358 . G <*> 0 . DP=22;I16=14,8,0,0,810,30184,0,0,1320,79200,0,0,445,10215,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,21,200:7:0 0,18,187:6:0 +X 3359 . T <*> 0 . DP=23;I16=13,8,0,0,743,26737,0,0,1260,75600,0,0,404,9318,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,21,194:7:0 0,15,162:5:0 +X 3360 . G <*> 0 . DP=23;I16=15,8,0,0,822,30058,0,0,1380,82800,0,0,436,9932,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,186:7:0 0,18,175:6:0 +X 3361 . G <*> 0 . DP=22;I16=15,7,0,0,751,26793,0,0,1320,79200,0,0,433,9819,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,218:9:0 0,21,187:7:0 0,18,175:6:0 +X 3362 . C <*> 0 . DP=22;I16=15,7,0,0,768,27462,0,0,1320,79200,0,0,430,9724,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,230:9:0 0,21,178:7:0 0,18,173:6:0 +X 3363 . G <*> 0 . DP=21;I16=14,7,0,0,662,21572,0,0,1260,75600,0,0,428,9646,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,194:9:0 0,18,155:6:0 0,18,161:6:0 +X 3364 . C <*> 0 . DP=21;I16=14,7,0,0,818,32184,0,0,1260,75600,0,0,423,9437,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,18,191:6:0 0,18,194:6:0 +X 3365 . A <*> 0 . DP=21;I16=14,7,0,0,791,29983,0,0,1260,75600,0,0,418,9250,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,226:9:0 0,18,186:6:0 0,18,190:6:0 +X 3366 . T <*> 0 . DP=21;I16=14,7,0,0,759,28053,0,0,1260,75600,0,0,413,9085,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,221:9:0 0,18,185:6:0 0,18,177:6:0 +X 3367 . G <*> 0 . DP=21;I16=14,7,0,0,767,28539,0,0,1260,75600,0,0,408,8942,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,235:9:0 0,18,185:6:0 0,18,169:6:0 +X 3368 . C <*> 0 . DP=21;I16=14,7,0,0,807,31329,0,0,1260,75600,0,0,403,8821,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,245:9:0 0,18,181:6:0 0,18,189:6:0 +X 3369 . C <*> 0 . DP=21;I16=14,7,0,0,789,30271,0,0,1260,75600,0,0,398,8722,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,18,186:6:0 0,18,193:6:0 +X 3370 . T <*> 0 . DP=21;I16=13,7,0,0,798,31960,0,0,1200,72000,0,0,392,8596,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,18,201:6:0 0,15,178:5:0 +X 3371 . G <*> 0 . DP=20;I16=13,7,0,0,739,27875,0,0,1200,72000,0,0,387,8493,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,18,173:6:0 0,15,169:5:0 +X 3372 . T <*> 0 . DP=20;I16=13,6,0,0,693,25677,0,0,1140,68400,0,0,359,7883,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,220:9:0 0,15,154:5:0 0,15,167:5:0 +X 3373 . A <*> 0 . DP=20;I16=13,7,0,0,729,27019,0,0,1200,72000,0,0,375,8253,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,226:9:0 0,18,162:6:0 0,15,174:5:0 +X 3374 . A <*> 0 . DP=19;I16=13,6,0,0,719,27437,0,0,1140,68400,0,0,369,8115,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,225:9:0 0,15,167:5:0 0,15,164:5:0 +X 3375 . T <*> 0 . DP=20;I16=12,6,0,0,683,26039,0,0,1080,64800,0,0,337,7321,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,15,155:5:0 0,15,172:5:0 +X 3376 . C <*> 0 . DP=20;I16=13,7,0,0,739,27867,0,0,1200,72000,0,0,356,7796,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,254:10:0 0,15,146:5:0 0,15,173:5:0 +X 3377 . C <*> 0 . DP=20;I16=13,7,0,0,741,27905,0,0,1200,72000,0,0,350,7666,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,15,149:5:0 0,15,173:5:0 +X 3378 . C <*> 0 . DP=20;I16=13,7,0,0,775,30179,0,0,1200,72000,0,0,343,7507,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,161:5:0 0,15,172:5:0 +X 3379 . A <*> 0 . DP=20;I16=13,7,0,0,736,27530,0,0,1200,72000,0,0,336,7370,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,245:10:0 0,15,157:5:0 0,15,169:5:0 +X 3380 . G <*> 0 . DP=19;I16=13,6,0,0,729,28249,0,0,1140,68400,0,0,330,7254,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,15,157:5:0 0,15,178:5:0 +X 3381 . C <*> 0 . DP=19;I16=13,6,0,0,742,29288,0,0,1140,68400,0,0,324,7158,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,15,155:5:0 0,15,178:5:0 +X 3382 . T <*> 0 . DP=17;I16=12,5,0,0,649,25245,0,0,1020,61200,0,0,320,7080,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,222:9:0 0,9,105:3:0 0,15,184:5:0 +X 3383 . A <*> 0 . DP=17;I16=12,4,0,0,556,19808,0,0,960,57600,0,0,291,6393,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,196:9:0 0,6,71:2:0 0,15,167:5:0 +X 3384 . C <*> 0 . DP=19;I16=14,5,0,0,701,26181,0,0,1140,68400,0,0,311,6923,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,235:10:0 0,9,98:3:0 0,18,187:6:0 +X 3385 . T <*> 0 . DP=19;I16=14,5,0,0,730,28456,0,0,1140,68400,0,0,307,6797,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,237:10:0 0,9,109:3:0 0,18,195:6:0 +X 3386 . T <*> 0 . DP=19;I16=14,5,0,0,642,22450,0,0,1140,68400,0,0,302,6642,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,197:10:0 0,9,104:3:0 0,18,188:6:0 +X 3387 . G <*> 0 . DP=20;I16=14,6,0,0,723,26761,0,0,1200,72000,0,0,296,6460,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,230:10:0 0,9,105:3:0 0,21,210:7:0 +X 3388 . G <*> 0 . DP=20;I16=14,6,0,0,705,25891,0,0,1200,72000,0,0,291,6303,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,225:10:0 0,9,109:3:0 0,21,202:7:0 +X 3389 . G <*> 0 . DP=18;I16=10,7,0,0,617,22635,0,0,1020,61200,0,0,270,5808,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,190:7:0 0,9,105:3:0 0,21,207:7:0 +X 3390 . A <*> 0 . DP=18;I16=11,7,0,0,631,22681,0,0,1080,64800,0,0,288,6056,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,200:8:0 0,9,105:3:0 0,21,198:7:0 +X 3391 . A <*> 0 . DP=18;I16=11,7,0,0,663,24951,0,0,1080,64800,0,0,287,5965,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,192:8:0 0,9,113:3:0 0,21,224:7:0 +X 3392 . G <*> 0 . DP=18;I16=11,7,0,0,666,25104,0,0,1080,64800,0,0,286,5896,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,211:8:0 0,9,103:3:0 0,21,216:7:0 +X 3393 . C <*> 0 . DP=18;I16=11,7,0,0,686,26472,0,0,1080,64800,0,0,284,5800,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,222:8:0 0,9,106:3:0 0,21,214:7:0 +X 3394 . T <*> 0 . DP=18;I16=11,7,0,0,699,27481,0,0,1080,64800,0,0,282,5728,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,219:8:0 0,9,114:3:0 0,21,222:7:0 +X 3395 . G <*> 0 . DP=17;I16=10,7,0,0,656,25512,0,0,1020,61200,0,0,281,5679,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,205:7:0 0,9,105:3:0 0,21,222:7:0 +X 3396 . A <*> 0 . DP=17;I16=10,7,0,0,644,25446,0,0,1020,61200,0,0,280,5652,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,182:7:0 0,9,119:3:0 0,21,232:7:0 +X 3397 . G <*> 0 . DP=17;I16=10,7,0,0,633,23895,0,0,1020,61200,0,0,279,5647,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,193:7:0 0,9,107:3:0 0,21,218:7:0 +X 3398 . G <*> 0 . DP=16;I16=10,6,0,0,610,23380,0,0,960,57600,0,0,279,5663,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,170:6:0 0,9,110:3:0 0,21,215:7:0 +X 3399 . G <*> 0 . DP=17;I16=10,6,0,0,585,21729,0,0,960,57600,0,0,270,5618,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,147:5:0 0,12,122:4:0 0,21,216:7:0 +X 3400 . A <*> 0 . DP=17;I16=10,6,0,0,576,21400,0,0,960,57600,0,0,264,5500,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,136:5:0 0,12,131:4:0 0,21,213:7:0 +X 3401 . T <*> 0 . DP=17;I16=11,6,0,0,605,22159,0,0,1020,61200,0,0,280,5784,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,146:6:0 0,12,131:4:0 0,21,216:7:0 +X 3402 . G <*> 0 . DP=17;I16=11,6,0,0,638,24150,0,0,1020,61200,0,0,280,5832,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,172:6:0 0,12,130:4:0 0,21,213:7:0 +X 3403 . A <*> 0 . DP=16;I16=9,6,0,0,579,22815,0,0,900,54000,0,0,276,5874,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,139:5:0 0,12,140:4:0 0,18,205:6:0 +X 3404 . G <*> 0 . DP=16;I16=10,6,0,0,564,20652,0,0,960,57600,0,0,281,5935,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,148:6:0 0,12,131:4:0 0,18,186:6:0 +X 3405 . A <*> 0 . DP=16;I16=10,6,0,0,560,20158,0,0,960,57600,0,0,281,5991,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,157:6:0 0,12,124:4:0 0,18,179:6:0 +X 3406 . A <*> 0 . DP=16;I16=10,6,0,0,568,20556,0,0,960,57600,0,0,281,6067,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,150:6:0 0,12,129:4:0 0,18,186:6:0 +X 3407 . C <*> 0 . DP=17;I16=11,6,0,0,591,21225,0,0,1020,61200,0,0,281,6163,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,178:7:0 0,12,106:4:0 0,18,183:6:0 +X 3408 . T <*> 0 . DP=17;I16=11,6,0,0,632,23754,0,0,1020,61200,0,0,282,6280,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,177:7:0 0,12,133:4:0 0,18,189:6:0 +X 3409 . G <*> 0 . DP=16;I16=10,6,0,0,599,22667,0,0,960,57600,0,0,283,6369,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,172:6:0 0,12,119:4:0 0,18,192:6:0 +X 3410 . C <*> 0 . DP=16;I16=10,6,0,0,585,21685,0,0,960,57600,0,0,282,6378,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,174:6:0 0,12,126:4:0 0,18,176:6:0 +X 3411 . T <*> 0 . DP=15;I16=9,6,0,0,578,22492,0,0,900,54000,0,0,282,6404,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,165:6:0 0,9,114:3:0 0,18,196:6:0 +X 3412 . T <*> 0 . DP=15;I16=9,6,0,0,546,20202,0,0,900,54000,0,0,283,6445,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,148:5:0 0,12,120:4:0 0,18,189:6:0 +X 3413 . G <*> 0 . DP=15;I16=9,6,0,0,559,21023,0,0,900,54000,0,0,283,6401,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,158:5:0 0,12,124:4:0 0,18,184:6:0 +X 3414 . A <*> 0 . DP=15;I16=9,6,0,0,512,17878,0,0,900,54000,0,0,283,6373,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,148:5:0 0,12,116:4:0 0,18,166:6:0 +X 3415 . A <*> 0 . DP=16;I16=9,7,0,0,544,19656,0,0,960,57600,0,0,282,6310,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,142:5:0 0,12,132:4:0 0,21,179:7:0 +X 3416 . C <*> 0 . DP=16;I16=9,7,0,0,562,20168,0,0,960,57600,0,0,282,6262,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,143:5:0 0,12,127:4:0 0,21,191:7:0 +X 3417 . C <*> 0 . DP=16;I16=9,7,0,0,566,20666,0,0,960,57600,0,0,282,6230,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,147:5:0 0,12,126:4:0 0,21,192:7:0 +X 3418 . T <*> 0 . DP=17;I16=10,5,0,0,557,21637,0,0,900,54000,0,0,268,5988,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,150:5:0 0,15,148:5:0 0,15,176:5:0 +X 3419 . G <*> 0 . DP=17;I16=10,7,0,0,594,21642,0,0,1020,61200,0,0,310,6836,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,161:6:0 0,15,140:5:0 0,18,190:6:0 +X 3420 . G <*> 0 . DP=17;I16=10,7,0,0,596,21580,0,0,1020,61200,0,0,312,6850,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,172:6:0 0,15,132:5:0 0,18,188:6:0 +X 3421 . G <*> 0 . DP=18;I16=10,8,0,0,633,22781,0,0,1049,62041,0,0,314,6880,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,21,184:7:0 0,15,138:5:0 0,18,191:6:0 +X 3422 . A <*> 0 . DP=18;I16=9,8,0,0,576,20954,0,0,989,58441,0,0,302,6702,0,0;QS=3,0;MQSB=0.91051;MQ0F=0 PL:DP:DV 0,18,167:6:0 0,15,130:5:0 0,18,188:6:0 +X 3423 . G <*> 0 . DP=18;I16=9,9,0,0,651,24391,0,0,1049,62041,0,0,305,6747,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,21,200:7:0 0,15,149:5:0 0,18,183:6:0 +X 3424 . G <*> 0 . DP=18;I16=8,8,0,0,555,20175,0,0,929,54841,0,0,275,6105,0,0;QS=3,0;MQSB=0.915545;MQ0F=0 PL:DP:DV 0,18,161:6:0 0,15,141:5:0 0,15,169:5:0 +X 3425 . C <*> 0 . DP=18;I16=9,8,0,0,594,21676,0,0,1020,61200,0,0,307,6779,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,168:6:0 0,15,142:5:0 0,18,186:6:0 +X 3426 . A <*> 0 . DP=18;I16=9,8,0,0,633,23967,0,0,1020,61200,0,0,308,6774,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,172:6:0 0,15,151:5:0 0,18,202:6:0 +X 3427 . G <*> 0 . DP=18;I16=9,9,0,0,655,24639,0,0,1049,62041,0,0,315,6823,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,21,209:7:0 0,15,144:5:0 0,18,184:6:0 +X 3428 . A <*> 0 . DP=18;I16=9,7,0,0,573,21235,0,0,960,57600,0,0,305,6793,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,158:5:0 0,15,147:5:0 0,18,178:6:0 +X 3429 . C <*> 0 . DP=17;I16=8,9,0,0,516,16610,0,0,989,58441,0,0,320,6930,0,0;QS=3,0;MQSB=0.928603;MQ0F=0 PL:DP:DV 0,21,176:7:0 0,15,125:5:0 0,15,124:5:0 +X 3430 . G <*> 0 . DP=18;I16=9,9,0,0,539,17155,0,0,1049,62041,0,0,323,7011,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,24,181:8:0 0,15,113:5:0 0,15,144:5:0 +X 3431 . T <*> 0 . DP=18;I16=9,9,0,0,651,24101,0,0,1049,62041,0,0,327,7111,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,24,210:8:0 0,15,139:5:0 0,15,166:5:0 +X 3432 . T <*> 0 . DP=18;I16=8,9,0,0,577,20601,0,0,989,58441,0,0,306,6606,0,0;QS=3,0;MQSB=0.928603;MQ0F=0 PL:DP:DV 0,21,162:7:0 0,15,144:5:0 0,15,165:5:0 +X 3433 . G <*> 0 . DP=18;I16=9,9,0,0,623,22589,0,0,1049,62041,0,0,334,7320,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,24,199:8:0 0,15,138:5:0 0,15,164:5:0 +X 3434 . C <*> 0 . DP=18;I16=10,7,0,0,582,20838,0,0,1020,61200,0,0,324,7208,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,208:8:0 0,15,130:5:0 0,12,137:4:0 +X 3435 . A <*> 0 . DP=18;I16=10,8,0,0,595,21619,0,0,1049,62041,0,0,341,7453,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,27,185:9:0 0,15,150:5:0 0,12,151:4:0 +X 3436 . G <*> 0 . DP=18;I16=10,8,0,0,617,22277,0,0,1049,62041,0,0,345,7549,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,27,218:9:0 0,15,146:5:0 0,12,133:4:0 +X 3437 . T G,<*> 0 . DP=18;I16=10,7,0,1,594,21168,16,256,1020,61200,29,841,333,7409,16,256;QS=2.94286,0.0571429,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.906029;BQB=1;MQ0F=0 PL:DP:DV 0,11,188,24,191,195:9:1 0,15,148,15,148,148:5:0 0,12,132,12,132,132:4:0 +X 3438 . G <*> 0 . DP=18;I16=10,7,0,0,622,23296,0,0,1020,61200,0,0,335,7461,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,215:8:0 0,15,152:5:0 0,12,140:4:0 +X 3439 . A <*> 0 . DP=18;I16=10,8,0,0,619,22965,0,0,1049,62041,0,0,355,7853,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,27,215:9:0 0,15,153:5:0 0,12,132:4:0 +X 3440 . G <*> 0 . DP=18;I16=10,7,0,0,610,22660,0,0,1020,61200,0,0,339,7613,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,15,143:5:0 0,12,131:4:0 +X 3441 . C <*> 0 . DP=18;I16=10,6,0,0,585,22165,0,0,960,57600,0,0,315,7037,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,226:8:0 0,15,140:5:0 0,9,115:3:0 +X 3442 . T <*> 0 . DP=20;I16=11,9,0,0,670,24716,0,0,1138,66482,0,0,362,8166,0,0;QS=3,0;MQSB=0.997118;MQ0F=0 PL:DP:DV 0,33,248:11:0 0,15,143:5:0 0,12,128:4:0 +X 3443 . G <*> 0 . DP=20;I16=11,9,0,0,708,26092,0,0,1138,66482,0,0,366,8288,0,0;QS=3,0;MQSB=0.997118;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,143:5:0 0,12,137:4:0 +X 3444 . A <*> 0 . DP=20;I16=11,9,0,0,698,25978,0,0,1138,66482,0,0,369,8379,0,0;QS=3,0;MQSB=0.997118;MQ0F=0 PL:DP:DV 0,33,244:11:0 0,15,161:5:0 0,12,131:4:0 +X 3445 . G <*> 0 . DP=20;I16=11,9,0,0,718,26590,0,0,1138,66482,0,0,372,8488,0,0;QS=3,0;MQSB=0.997118;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,153:5:0 0,12,132:4:0 +X 3446 . A <*> 0 . DP=20;I16=10,8,0,0,635,23323,0,0,1049,62041,0,0,325,7365,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,27,222:9:0 0,15,154:5:0 0,12,131:4:0 +X 3447 . T <*> 0 . DP=20;I16=11,8,0,0,669,24331,0,0,1109,65641,0,0,352,8084,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,30,230:10:0 0,15,150:5:0 0,12,137:4:0 +X 3448 . C <*> 0 . DP=19;I16=10,8,0,0,641,23693,0,0,1049,62041,0,0,355,8193,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,113:4:0 0,12,128:4:0 +X 3449 . A <*> 0 . DP=19;I16=10,8,0,0,565,19185,0,0,1049,62041,0,0,357,8265,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,30,217:10:0 0,12,111:4:0 0,12,119:4:0 +X 3450 . C <*> 0 . DP=18;I16=8,8,0,0,520,17846,0,0,898,52082,0,0,334,7674,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,229:10:0 0,6,70:2:0 0,12,106:4:0 +X 3451 . G <*> 0 . DP=18;I16=10,7,0,0,528,17178,0,0,989,58441,0,0,361,8345,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,30,226:10:0 0,9,56:3:0 0,12,123:4:0 +X 3452 . C <*> 0 . DP=18;I16=10,8,0,0,657,24597,0,0,1018,59282,0,0,388,9028,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,84:3:0 0,12,128:4:0 +X 3453 . C <*> 0 . DP=18;I16=10,8,0,0,663,24951,0,0,1018,59282,0,0,390,9098,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,90:3:0 0,12,125:4:0 +X 3454 . A <*> 0 . DP=18;I16=10,8,0,0,614,21898,0,0,1018,59282,0,0,392,9180,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,33,251:11:0 0,9,90:3:0 0,12,128:4:0 +X 3455 . C <*> 0 . DP=18;I16=10,8,0,0,650,23968,0,0,1018,59282,0,0,394,9274,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,90:3:0 0,12,127:4:0 +X 3456 . T <*> 0 . DP=18;I16=10,8,0,0,607,21961,0,0,1018,59282,0,0,395,9329,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,33,243:11:0 0,9,88:3:0 0,12,135:4:0 +X 3457 . G <*> 0 . DP=18;I16=9,7,0,0,549,19861,0,0,898,52082,0,0,346,8144,0,0;QS=3,0;MQSB=0.994413;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,6,63:2:0 0,9,107:3:0 +X 3458 . C <*> 0 . DP=18;I16=10,8,0,0,638,23236,0,0,1018,59282,0,0,397,9469,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,81:3:0 0,12,125:4:0 +X 3459 . A C,<*> 0 . DP=17;I16=9,7,0,1,520,18390,22,484,929,54841,29,841,372,8830,25,625;QS=2.92971,0.0702875,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.998843;BQB=1;MQ0F=0 PL:DP:DV 0,8,201,27,204,213:10:1 0,9,84,9,84,84:3:0 0,12,116,12,116,116:4:0 +X 3460 . C <*> 0 . DP=17;I16=8,7,0,0,554,20952,0,0,869,51241,0,0,345,8103,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,6,65:2:0 0,12,131:4:0 +X 3461 . T <*> 0 . DP=17;I16=9,7,0,0,591,22805,0,0,929,54841,0,0,368,8638,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,27,231:9:0 0,9,103:3:0 0,12,133:4:0 +X 3462 . C <*> 0 . DP=18;I16=9,9,0,0,672,25486,0,0,1018,59282,0,0,391,9185,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,90:3:0 0,12,130:4:0 +X 3463 . C <*> 0 . DP=18;I16=8,9,0,0,584,21458,0,0,958,55682,0,0,369,8671,0,0;QS=3,0;MQSB=0.998843;MQ0F=0 PL:DP:DV 0,30,244:10:0 0,9,86:3:0 0,12,132:4:0 +X 3464 . A <*> 0 . DP=18;I16=9,9,0,0,628,23490,0,0,1018,59282,0,0,387,8973,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,244:11:0 0,9,96:3:0 0,12,142:4:0 +X 3465 . G <*> 0 . DP=19;I16=9,9,0,0,642,24008,0,0,1018,59282,0,0,384,8842,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,91:3:0 0,12,135:4:0 +X 3466 . C <*> 0 . DP=20;I16=9,10,0,0,682,25218,0,0,1047,60123,0,0,378,8588,0,0;QS=3,0;MQSB=0.904084;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,101:3:0 0,15,147:5:0 +X 3467 . C <*> 0 . DP=20;I16=10,9,0,0,685,25919,0,0,1047,60123,0,0,397,9139,0,0;QS=3,0;MQSB=0.948064;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,115:4:0 0,15,154:5:0 +X 3468 . T <*> 0 . DP=20;I16=10,9,0,0,672,25426,0,0,1047,60123,0,0,374,8410,0,0;QS=3,0;MQSB=0.948064;MQ0F=0 PL:DP:DV 0,30,246:10:0 0,12,126:4:0 0,15,164:5:0 +X 3469 . G <*> 0 . DP=21;I16=10,11,0,0,788,30064,0,0,1167,67323,0,0,396,8924,0,0;QS=3,0;MQSB=0.914611;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,146:5:0 0,15,163:5:0 +X 3470 . G <*> 0 . DP=22;I16=11,11,0,0,796,29754,0,0,1196,68164,0,0,393,8781,0,0;QS=3,0;MQSB=0.770381;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,131:5:0 0,15,161:5:0 +X 3471 . G <*> 0 . DP=23;I16=12,11,0,0,801,29083,0,0,1256,71764,0,0,391,8657,0,0;QS=3,0;MQSB=0.811552;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,133:5:0 0,15,151:5:0 +X 3472 . C <*> 0 . DP=23;I16=12,11,0,0,757,26535,0,0,1256,71764,0,0,390,8554,0,0;QS=3,0;MQSB=0.811552;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,145:5:0 0,15,136:5:0 +X 3473 . A <*> 0 . DP=23;I16=11,11,0,0,777,28175,0,0,1196,68164,0,0,379,8373,0,0;QS=3,0;MQSB=0.770381;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,148:5:0 0,15,153:5:0 +X 3474 . A <*> 0 . DP=23;I16=12,11,0,0,807,29181,0,0,1256,71764,0,0,388,8414,0,0;QS=3,0;MQSB=0.811552;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,150:5:0 0,15,155:5:0 +X 3475 . C <*> 0 . DP=22;I16=12,10,0,0,737,25849,0,0,1196,68164,0,0,387,8327,0,0;QS=3,0;MQSB=0.838545;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,137:5:0 0,15,143:5:0 +X 3476 . A <*> 0 . DP=22;I16=12,10,0,0,790,29312,0,0,1196,68164,0,0,386,8262,0,0;QS=3,0;MQSB=0.838545;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,149:5:0 0,15,154:5:0 +X 3477 . G <*> 0 . DP=22;I16=11,10,0,0,755,28237,0,0,1136,64564,0,0,363,7735,0,0;QS=3,0;MQSB=0.799507;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,126:4:0 0,15,153:5:0 +X 3478 . A <*> 0 . DP=25;I16=13,11,0,0,857,31637,0,0,1316,75364,0,0,384,8198,0,0;QS=3,0;MQSB=0.845496;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,167:6:0 0,18,190:6:0 +X 3479 . G <*> 0 . DP=25;I16=12,10,0,0,783,28623,0,0,1227,70923,0,0,355,7701,0,0;QS=3,0;MQSB=0.613159;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,152:5:0 0,18,160:6:0 +X 3480 . T <*> 0 . DP=25;I16=13,11,0,0,788,27124,0,0,1316,75364,0,0,393,8531,0,0;QS=3,0;MQSB=0.845496;MQ0F=0 PL:DP:DV 0,33,249:11:0 0,21,182:7:0 0,18,155:6:0 +X 3481 . A <*> 0 . DP=25;I16=12,12,0,0,858,30884,0,0,1347,78123,0,0,397,8685,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,194:7:0 0,15,148:5:0 +X 3482 . A <*> 0 . DP=25;I16=13,12,0,0,927,35013,0,0,1376,78964,0,0,412,8942,0,0;QS=3,0;MQSB=0.822311;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,202:7:0 0,18,182:6:0 +X 3483 . G <*> 0 . DP=25;I16=12,12,0,0,794,27410,0,0,1316,75364,0,0,412,9002,0,0;QS=3,0;MQSB=0.786628;MQ0F=0 PL:DP:DV 0,33,253:11:0 0,21,183:7:0 0,18,158:6:0 +X 3484 . A C,<*> 0 . DP=24;I16=12,9,0,1,710,25220,14,196,1198,70082,60,3600,346,7514,25,625;QS=2.93665,0.0633484,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.804615;BQB=1;MQ0F=0 PL:DP:DV 0,30,227,30,227,227:10:0 0,7,156,18,159,162:7:1 0,15,133,15,133,133:5:0 +X 3485 . C <*> 0 . DP=23;I16=11,11,0,0,766,27656,0,0,1196,68164,0,0,393,8573,0,0;QS=3,0;MQSB=0.770381;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,163:6:0 0,15,120:5:0 +X 3486 . T <*> 0 . DP=24;I16=12,10,0,0,799,30529,0,0,1196,68164,0,0,398,8756,0,0;QS=3,0;MQSB=0.838545;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,198:7:0 0,15,128:5:0 +X 3487 . C <*> 0 . DP=24;I16=10,11,0,0,724,27586,0,0,1167,67323,0,0,393,8905,0,0;QS=3,0;MQSB=0.914611;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,162:6:0 0,12,92:4:0 +X 3488 . T <*> 0 . DP=24;I16=12,10,0,0,742,27454,0,0,1196,68164,0,0,429,9571,0,0;QS=3,0;MQSB=0.838545;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,172:7:0 0,12,98:4:0 +X 3489 . G <*> 0 . DP=25;I16=13,11,0,0,778,28994,0,0,1285,72605,0,0,433,9675,0,0;QS=3,0;MQSB=0.97965;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,177:8:0 0,12,75:4:0 +X 3490 . T C,<*> 0 . DP=27;I16=14,10,1,0,806,28886,25,625,1254,69846,60,3600,427,9659,12,144;QS=2.90775,0.0922509,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.962269;BQB=1;MQ0F=0 PL:DP:DV 0,39,255,39,255,255:13:0 0,2,168,24,171,183:9:1 0,9,85,9,85,85:3:0 +X 3491 . C <*> 0 . DP=28;I16=15,11,0,0,864,31232,0,0,1405,79805,0,0,445,9903,0,0;QS=3,0;MQSB=0.753395;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,197:9:0 0,9,78:3:0 +X 3492 . T <*> 0 . DP=28;I16=15,11,0,0,852,31516,0,0,1405,79805,0,0,452,9986,0,0;QS=3,0;MQSB=0.753395;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,212:9:0 0,9,96:3:0 +X 3493 . C <*> 0 . DP=28;I16=15,12,0,0,891,32181,0,0,1434,80646,0,0,464,10124,0,0;QS=3,0;MQSB=0.908075;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,214:9:0 0,9,80:3:0 +X 3493 . CAAAAAAAAAAAAA CAAAAAAAAAAAA,CAAAAAAAAAAAAAA 0 . INDEL;IDV=2;IMF=0.125;DP=28;I16=9,9,0,2,443,11071,47,1129,1049,62041,89,4441,320,7120,30,650;QS=2.81818,0.0909091,0.0909091;VDB=0.504964;SGB=0.346553;MQSB=0.997118;MQ0F=0 PL:DP:DV 0,19,37,19,40,37:11:2 0,18,39,18,39,39:6:0 0,9,23,9,23,23:3:0 +X 3494 . A <*> 0 . DP=30;I16=15,12,0,0,970,37408,0,0,1465,83405,0,0,440,9568,0,0;QS=3,0;MQSB=0.723173;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,220:9:0 0,12,117:4:0 +X 3495 . A <*> 0 . DP=31;I16=15,13,0,0,966,36178,0,0,1525,87005,0,0,472,10270,0,0;QS=3,0;MQSB=0.695496;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,210:9:0 0,15,129:5:0 +X 3496 . A <*> 0 . DP=31;I16=15,13,0,0,974,36928,0,0,1525,87005,0,0,477,10281,0,0;QS=3,0;MQSB=0.695496;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,207:9:0 0,15,138:5:0 +X 3497 . A <*> 0 . DP=32;I16=14,14,0,0,1015,39525,0,0,1525,87005,0,0,460,9834,0,0;QS=3,0;MQSB=0.62781;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,208:8:0 0,18,148:6:0 +X 3498 . A <*> 0 . DP=32;I16=14,14,0,0,982,37264,0,0,1556,89764,0,0,460,9628,0,0;QS=3,0;MQSB=0.813104;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,220:9:0 0,15,115:5:0 +X 3499 . A <*> 0 . DP=32;I16=14,14,0,0,1024,40072,0,0,1525,87005,0,0,489,10267,0,0;QS=3,0;MQSB=0.62781;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,222:8:0 0,18,144:6:0 +X 3500 . A <*> 0 . DP=31;I16=14,14,0,0,995,38097,0,0,1525,87005,0,0,494,10316,0,0;QS=3,0;MQSB=0.62781;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,214:8:0 0,18,150:6:0 +X 3501 . A <*> 0 . DP=31;I16=14,14,0,0,1017,39845,0,0,1525,87005,0,0,499,10399,0,0;QS=3,0;MQSB=0.62781;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,221:8:0 0,18,149:6:0 +X 3502 . A <*> 0 . DP=31;I16=14,14,0,0,1051,41955,0,0,1525,87005,0,0,504,10516,0,0;QS=3,0;MQSB=0.62781;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,223:8:0 0,18,154:6:0 +X 3503 . A <*> 0 . DP=31;I16=14,14,0,0,1038,40832,0,0,1525,87005,0,0,509,10667,0,0;QS=3,0;MQSB=0.62781;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,229:8:0 0,18,155:6:0 +X 3504 . A <*> 0 . DP=31;I16=14,14,0,0,1037,41235,0,0,1525,87005,0,0,512,10750,0,0;QS=3,0;MQSB=0.62781;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,229:8:0 0,18,145:6:0 +X 3505 . A <*> 0 . DP=31;I16=14,14,0,0,1039,40959,0,0,1525,87005,0,0,514,10814,0,0;QS=3,0;MQSB=0.62781;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,233:8:0 0,18,156:6:0 +X 3506 . A <*> 0 . DP=32;I16=11,13,0,0,889,34265,0,0,1378,80882,0,0,427,9079,0,0;QS=3,0;MQSB=0.998323;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,201:6:0 0,18,158:6:0 +X 3507 . T <*> 0 . DP=31;I16=10,17,0,0,995,38431,0,0,1527,88923,0,0,493,10499,0,0;QS=3,0;MQSB=0.997168;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,187:6:0 0,18,153:6:0 +X 3508 . C <*> 0 . DP=31;I16=10,17,0,0,997,40091,0,0,1527,88923,0,0,499,10675,0,0;QS=3,0;MQSB=0.997168;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,160:6:0 0,15,119:5:0 +X 3509 . A <*> 0 . DP=30;I16=11,17,0,0,995,37147,0,0,1556,89764,0,0,529,11459,0,0;QS=3,0;MQSB=0.960952;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,175:6:0 0,15,125:5:0 +X 3510 . C A,<*> 0 . DP=29;I16=9,17,1,0,959,37997,40,1600,1498,88082,29,841,483,10351,25,625;QS=2.95246,0.047541,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.997168;BQB=1;MQ0F=0 PL:DP:DV 0,19,255,45,255,255:16:1 0,18,150,18,150,150:6:0 0,15,119,15,119,119:5:0 +X 3511 . A <*> 0 . DP=32;I16=11,17,0,0,923,33125,0,0,1587,92523,0,0,512,11150,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,169:6:0 0,15,115:5:0 +X 3512 . C <*> 0 . DP=32;I16=10,18,0,0,1058,42208,0,0,1618,95282,0,0,493,10733,0,0;QS=3,0;MQSB=0.891417;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,181:6:0 0,15,131:5:0 +X 3513 . C A,<*> 0 . DP=32;I16=10,18,1,0,1074,42406,13,169,1618,95282,29,841,498,10926,25,625;QS=2.98,0.02,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.995968;BQB=1;MQ0F=0 PL:DP:DV 0,39,255,51,255,255:18:1 0,18,190,18,190,190:6:0 0,15,136,15,136,136:5:0 +X 3514 . A <*> 0 . DP=33;I16=11,19,0,0,1101,42213,0,0,1707,99723,0,0,528,11778,0,0;QS=3,0;MQSB=0.997918;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,199:7:0 0,15,132:5:0 +X 3515 . T <*> 0 . DP=33;I16=12,19,0,0,1130,43380,0,0,1736,100564,0,0,557,12563,0,0;QS=3,0;MQSB=0.960505;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,192:7:0 0,15,126:5:0 +X 3516 . T <*> 0 . DP=34;I16=14,17,0,0,1147,44331,0,0,1767,103323,0,0,536,12078,0,0;QS=3,0;MQSB=0.924242;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,203:7:0 0,15,133:5:0 +X 3517 . T <*> 0 . DP=34;I16=14,18,0,0,1183,46549,0,0,1796,104164,0,0,565,12773,0,0;QS=3,0;MQSB=0.988522;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,210:7:0 0,15,153:5:0 +X 3518 . T <*> 0 . DP=34;I16=14,18,0,0,1165,44867,0,0,1796,104164,0,0,568,12826,0,0;QS=3,0;MQSB=0.988522;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,203:7:0 0,15,141:5:0 +X 3519 . G <*> 0 . DP=33;I16=13,18,0,0,1158,46678,0,0,1736,100564,0,0,572,12912,0,0;QS=3,0;MQSB=0.980167;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,18,189:6:0 0,15,154:5:0 +X 3520 . G <*> 0 . DP=33;I16=12,18,0,0,1111,42471,0,0,1707,99723,0,0,552,12438,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,183:6:0 0,15,151:5:0 +X 3521 . C <*> 0 . DP=32;I16=11,17,0,0,1077,43755,0,0,1649,98041,0,0,530,11850,0,0;QS=3,0;MQSB=0.967085;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,185:6:0 0,15,143:5:0 +X 3522 . T <*> 0 . DP=32;I16=12,17,0,0,1125,46329,0,0,1678,98882,0,0,552,12274,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,199:6:0 0,15,158:5:0 +X 3523 . T <*> 0 . DP=31;I16=11,16,0,0,996,38204,0,0,1558,91682,0,0,544,12286,0,0;QS=3,0;MQSB=0.992419;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,193:6:0 0,15,145:5:0 +X 3524 . C <*> 0 . DP=31;I16=11,16,0,0,1067,43883,0,0,1589,94441,0,0,538,11960,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,192:6:0 0,15,152:5:0 +X 3525 . A <*> 0 . DP=31;I16=13,16,0,0,1132,46402,0,0,1678,98882,0,0,556,12250,0,0;QS=3,0;MQSB=0.997839;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,200:6:0 0,15,165:5:0 +X 3526 . G <*> 0 . DP=31;I16=12,16,0,0,1090,43912,0,0,1649,98041,0,0,543,12053,0,0;QS=3,0;MQSB=0.96195;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,181:6:0 0,15,147:5:0 +X 3527 . A <*> 0 . DP=31;I16=13,16,0,0,1068,41740,0,0,1678,98882,0,0,560,12334,0,0;QS=3,0;MQSB=0.997839;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,170:6:0 0,15,157:5:0 +X 3528 . T <*> 0 . DP=31;I16=13,16,0,0,1076,41782,0,0,1678,98882,0,0,561,12369,0,0;QS=3,0;MQSB=0.997839;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,193:6:0 0,15,152:5:0 +X 3529 . T <*> 0 . DP=31;I16=12,16,0,0,1016,38674,0,0,1649,98041,0,0,550,12290,0,0;QS=3,0;MQSB=0.96195;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,184:6:0 0,15,154:5:0 +X 3530 . G <*> 0 . DP=30;I16=12,17,0,0,1070,40570,0,0,1709,101641,0,0,578,13032,0,0;QS=3,0;MQSB=0.965321;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,176:6:0 0,18,175:6:0 +X 3531 . C A,<*> 0 . DP=31;I16=13,17,1,0,1080,40304,38,1444,1738,102482,29,841,607,13801,10,100;QS=2.95773,0.0422741,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.924242;BQB=1;MQ0F=0 PL:DP:DV 0,28,255,54,255,255:19:1 0,18,172,18,172,172:6:0 0,18,175,18,175,175:6:0 +X 3532 . A <*> 0 . DP=31;I16=14,17,0,0,1136,42380,0,0,1767,103323,0,0,619,14003,0,0;QS=3,0;MQSB=0.924242;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,180:6:0 0,18,184:6:0 +X 3533 . T <*> 0 . DP=31;I16=13,17,0,0,1074,39206,0,0,1738,102482,0,0,595,13457,0,0;QS=3,0;MQSB=0.996503;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,180:6:0 0,18,176:6:0 +X 3534 . A <*> 0 . DP=30;I16=12,17,0,0,1014,36168,0,0,1678,98882,0,0,597,13561,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,165:6:0 0,18,175:6:0 +X 3535 . T <*> 0 . DP=31;I16=14,17,0,0,1042,36456,0,0,1767,103323,0,0,624,14314,0,0;QS=3,0;MQSB=0.924242;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,162:6:0 0,18,164:6:0 +X 3536 . C <*> 0 . DP=31;I16=13,17,0,0,1102,41182,0,0,1738,102482,0,0,602,13842,0,0;QS=3,0;MQSB=0.996503;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,178:6:0 0,18,180:6:0 +X 3537 . C <*> 0 . DP=32;I16=13,17,0,0,1142,43828,0,0,1769,105241,0,0,598,13854,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,194:7:0 0,18,185:6:0 +X 3538 . T <*> 0 . DP=32;I16=14,17,0,0,1151,43471,0,0,1798,106082,0,0,603,13923,0,0;QS=3,0;MQSB=0.998229;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,211:7:0 0,18,185:6:0 +X 3539 . C <*> 0 . DP=32;I16=12,17,0,0,1077,40959,0,0,1709,101641,0,0,600,13994,0,0;QS=3,0;MQSB=0.965321;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,170:6:0 0,18,173:6:0 +X 3540 . C <*> 0 . DP=31;I16=13,17,0,0,1134,43546,0,0,1769,105241,0,0,603,14055,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,209:7:0 0,18,172:6:0 +X 3541 . T <*> 0 . DP=32;I16=13,18,0,0,1143,42901,0,0,1829,108841,0,0,604,14134,0,0;QS=3,0;MQSB=0.966712;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,224:8:0 0,18,187:6:0 +X 3542 . G <*> 0 . DP=32;I16=13,18,0,0,1152,43714,0,0,1829,108841,0,0,604,14134,0,0;QS=3,0;MQSB=0.966712;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,223:8:0 0,18,172:6:0 +X 3543 . C <*> 0 . DP=31;I16=13,17,0,0,1142,43818,0,0,1769,105241,0,0,605,14153,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,221:8:0 0,18,188:6:0 +X 3544 . A <*> 0 . DP=31;I16=13,17,0,0,1089,40065,0,0,1769,105241,0,0,606,14190,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,221:8:0 0,18,173:6:0 +X 3545 . A <*> 0 . DP=30;I16=13,16,0,0,1118,43688,0,0,1709,101641,0,0,607,14195,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,228:7:0 0,18,196:6:0 +X 3546 . G <*> 0 . DP=30;I16=14,16,0,0,1131,43425,0,0,1738,102482,0,0,630,14698,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,206:7:0 0,18,179:6:0 +X 3547 . G <*> 0 . DP=31;I16=13,17,0,0,1076,39798,0,0,1769,105241,0,0,607,14163,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,189:7:0 0,18,187:6:0 +X 3548 . A <*> 0 . DP=31;I16=13,17,0,0,1071,39059,0,0,1769,105241,0,0,608,14178,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,208:7:0 0,18,179:6:0 +X 3549 . T <*> 0 . DP=30;I16=13,16,0,0,1008,35928,0,0,1678,98882,0,0,605,13989,0,0;QS=3,0;MQSB=0.997839;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,180:6:0 0,15,152:5:0 +X 3550 . A <*> 0 . DP=30;I16=13,16,0,0,1061,39371,0,0,1709,101641,0,0,612,14270,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,194:7:0 0,15,173:5:0 +X 3551 . T <*> 0 . DP=30;I16=13,16,0,0,1026,36844,0,0,1709,101641,0,0,613,14295,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,192:7:0 0,15,162:5:0 +X 3552 . A <*> 0 . DP=30;I16=14,16,0,0,1080,39588,0,0,1738,102482,0,0,631,14627,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,202:7:0 0,15,158:5:0 +X 3553 . T A,<*> 0 . DP=30;I16=13,16,1,0,1047,38333,20,400,1709,101641,29,841,616,14398,16,256;QS=2.96795,0.0320513,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.999136;BQB=1;MQ0F=0 PL:DP:DV 0,34,255,51,255,255:18:1 0,18,178,18,178,178:6:0 0,18,183,18,183,183:6:0 +X 3554 . A <*> 0 . DP=30;I16=14,16,0,0,1063,38413,0,0,1738,102482,0,0,632,14602,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,185:6:0 0,18,179:6:0 +X 3555 . C <*> 0 . DP=30;I16=14,16,0,0,1021,35781,0,0,1738,102482,0,0,632,14574,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,169:6:0 0,18,163:6:0 +X 3556 . G <*> 0 . DP=30;I16=13,16,0,0,1014,36426,0,0,1709,101641,0,0,618,14350,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,168:6:0 0,18,173:6:0 +X 3557 . C <*> 0 . DP=31;I16=14,16,0,0,1001,34919,0,0,1769,105241,0,0,618,14342,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,140:6:0 0,18,165:6:0 +X 3558 . G <*> 0 . DP=31;I16=15,16,0,0,1036,35974,0,0,1798,106082,0,0,630,14476,0,0;QS=3,0;MQSB=0.999805;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,159:6:0 0,18,171:6:0 +X 3559 . T <*> 0 . DP=30;I16=14,16,0,0,1086,40202,0,0,1769,105241,0,0,619,14341,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,171:6:0 0,18,192:6:0 +X 3560 . G <*> 0 . DP=31;I16=14,16,0,0,1151,45035,0,0,1738,102482,0,0,611,14127,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,165:5:0 0,18,194:6:0 +X 3561 . A <*> 0 . DP=31;I16=15,16,0,0,1147,43431,0,0,1798,106082,0,0,626,14366,0,0;QS=3,0;MQSB=0.999805;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,186:6:0 0,18,196:6:0 +X 3562 . A <*> 0 . DP=31;I16=16,15,0,0,1157,43859,0,0,1798,106082,0,0,623,14257,0,0;QS=3,0;MQSB=0.999805;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,192:6:0 0,21,213:7:0 +X 3563 . A <*> 0 . DP=31;I16=16,15,0,0,1162,44010,0,0,1798,106082,0,0,620,14124,0,0;QS=3,0;MQSB=0.999805;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,192:6:0 0,21,216:7:0 +X 3564 . T <*> 0 . DP=31;I16=15,15,0,0,1132,43298,0,0,1769,105241,0,0,610,13932,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,192:6:0 0,21,214:7:0 +X 3565 . T <*> 0 . DP=32;I16=16,16,0,0,1163,42649,0,0,1858,109682,0,0,611,13791,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,189:6:0 0,21,212:7:0 +X 3566 . C <*> 0 . DP=32;I16=16,16,0,0,1162,43586,0,0,1858,109682,0,0,606,13596,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,181:6:0 0,21,209:7:0 +X 3567 . A <*> 0 . DP=32;I16=15,16,0,0,1181,45245,0,0,1829,108841,0,0,597,13375,0,0;QS=3,0;MQSB=0.957006;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,192:6:0 0,21,222:7:0 +X 3568 . A <*> 0 . DP=32;I16=15,16,0,0,1194,46670,0,0,1829,108841,0,0,592,13200,0,0;QS=3,0;MQSB=0.957006;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,204:6:0 0,21,228:7:0 +X 3569 . G <*> 0 . DP=31;I16=15,16,0,0,1164,44544,0,0,1829,108841,0,0,586,13006,0,0;QS=3,0;MQSB=0.957006;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,180:6:0 0,21,204:7:0 +X 3570 . T <*> 0 . DP=30;I16=14,15,0,0,1029,37527,0,0,1709,101641,0,0,572,12730,0,0;QS=3,0;MQSB=0.954405;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,136:4:0 0,21,213:7:0 +X 3571 . C <*> 0 . DP=28;I16=13,15,0,0,1066,41192,0,0,1649,98041,0,0,568,12564,0,0;QS=3,0;MQSB=0.956162;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,138:4:0 0,21,215:7:0 +X 3572 . A <*> 0 . DP=29;I16=13,16,0,0,1108,42566,0,0,1709,101641,0,0,564,12426,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,172:5:0 0,21,218:7:0 +X 3573 . A <*> 0 . DP=29;I16=13,16,0,0,1119,43403,0,0,1709,101641,0,0,558,12168,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,174:5:0 0,21,220:7:0 +X 3574 . T <*> 0 . DP=29;I16=13,16,0,0,1104,42220,0,0,1709,101641,0,0,552,11942,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,175:5:0 0,21,218:7:0 +X 3575 . G <*> 0 . DP=29;I16=13,16,0,0,1122,43748,0,0,1709,101641,0,0,546,11748,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,161:5:0 0,21,212:7:0 +X 3576 . A <*> 0 . DP=29;I16=13,16,0,0,1043,38405,0,0,1709,101641,0,0,540,11586,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,170:5:0 0,21,213:7:0 +X 3577 . C <*> 0 . DP=30;I16=13,17,0,0,1123,42529,0,0,1769,105241,0,0,534,11456,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,161:5:0 0,21,211:7:0 +X 3578 . A <*> 0 . DP=30;I16=13,17,0,0,1148,44236,0,0,1769,105241,0,0,529,11359,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,178:5:0 0,21,216:7:0 +X 3579 . A <*> 0 . DP=29;I16=13,16,0,0,1051,38961,0,0,1709,101641,0,0,524,11244,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,172:5:0 0,18,192:6:0 +X 3580 . A <*> 0 . DP=29;I16=13,16,0,0,1104,42344,0,0,1709,101641,0,0,519,11159,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,172:5:0 0,18,201:6:0 +X 3581 . T <*> 0 . DP=29;I16=13,16,0,0,1088,41226,0,0,1709,101641,0,0,513,11055,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,161:5:0 0,18,199:6:0 +X 3582 . C <*> 0 . DP=29;I16=13,16,0,0,1120,43616,0,0,1709,101641,0,0,506,10934,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,172:5:0 0,18,201:6:0 +X 3583 . A <*> 0 . DP=30;I16=14,16,0,0,1130,43606,0,0,1769,105241,0,0,498,10796,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,183:5:0 0,21,213:7:0 +X 3584 . G <*> 0 . DP=29;I16=12,16,0,0,1027,38895,0,0,1649,98041,0,0,487,10665,0,0;QS=3,0;MQSB=0.96195;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,137:4:0 0,21,209:7:0 +X 3585 . A <*> 0 . DP=31;I16=14,17,0,0,1057,37719,0,0,1829,108841,0,0,486,10616,0,0;QS=3,0;MQSB=0.962133;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,168:5:0 0,24,209:8:0 +X 3586 . A <*> 0 . DP=30;I16=14,15,0,0,1053,40043,0,0,1709,101641,0,0,477,10461,0,0;QS=3,0;MQSB=0.954405;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,174:5:0 0,24,213:8:0 +X 3587 . G A,<*> 0 . DP=29;I16=4,7,10,6,426,16884,555,20381,660,39600,960,57600,192,4420,280,5942;QS=1.32665,1.67335,0;VDB=0.902044;SGB=-3.91326;RPB=0.800999;MQB=1;MQSB=1;BQB=0.156944;MQ0F=0 PL:DP:DV 161,0,184,182,205,255:14:7 22,0,118,34,121,148:5:1 212,24,0,212,24,212:8:8 +X 3588 . A <*> 0 . DP=29;I16=14,14,0,0,999,36973,0,0,1680,100800,0,0,470,10254,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,166:5:0 0,24,215:8:0 +X 3589 . A <*> 0 . DP=28;I16=14,13,0,0,967,35935,0,0,1620,97200,0,0,467,10173,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,166:5:0 0,24,206:8:0 +X 3590 . A <*> 0 . DP=27;I16=13,13,0,0,948,35860,0,0,1560,93600,0,0,464,10072,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,146:4:0 0,24,211:8:0 +X 3591 . A <*> 0 . DP=26;I16=13,13,0,0,913,33539,0,0,1560,93600,0,0,459,9901,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,144:4:0 0,24,212:8:0 +X 3592 . A <*> 0 . DP=26;I16=13,13,0,0,893,32087,0,0,1560,93600,0,0,453,9711,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,143:4:0 0,24,199:8:0 +X 3593 . A <*> 0 . DP=26;I16=13,13,0,0,891,31363,0,0,1560,93600,0,0,447,9553,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,137:4:0 0,24,198:8:0 +X 3594 . C <*> 0 . DP=25;I16=12,12,0,0,910,34868,0,0,1440,86400,0,0,426,9170,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,142:4:0 0,24,216:8:0 +X 3595 . A <*> 0 . DP=24;I16=13,11,0,0,918,35274,0,0,1440,86400,0,0,438,9328,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,143:4:0 0,21,199:7:0 +X 3596 . T <*> 0 . DP=24;I16=13,11,0,0,837,30077,0,0,1440,86400,0,0,434,9258,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,138:4:0 0,21,188:7:0 +X 3597 . A <*> 0 . DP=24;I16=13,11,0,0,893,33549,0,0,1440,86400,0,0,430,9216,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,132:4:0 0,21,204:7:0 +X 3598 . T <*> 0 . DP=23;I16=12,10,0,0,778,28226,0,0,1320,79200,0,0,415,9005,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,140:4:0 0,21,162:7:0 +X 3599 . A <*> 0 . DP=23;I16=13,10,0,0,859,32403,0,0,1380,82800,0,0,425,9105,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,142:4:0 0,21,182:7:0 +X 3600 . T <*> 0 . DP=24;I16=14,10,0,0,872,32086,0,0,1435,85825,0,0,422,9036,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,139:4:0 0,21,183:7:0 +X 3601 . A <*> 0 . DP=24;I16=14,10,0,0,862,31424,0,0,1435,85825,0,0,420,8994,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,132:4:0 0,21,186:7:0 +X 3602 . T <*> 0 . DP=25;I16=15,10,0,0,873,31323,0,0,1495,89425,0,0,418,8980,0,0;QS=3,0;MQSB=0.962269;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,161:5:0 0,21,174:7:0 +X 3603 . A <*> 0 . DP=26;I16=15,11,0,0,907,32447,0,0,1555,93025,0,0,416,8944,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,151:5:0 0,24,216:8:0 +X 3604 . C <*> 0 . DP=27;I16=16,11,0,0,905,31199,0,0,1615,96625,0,0,415,8937,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,147:6:0 0,24,201:8:0 +X 3605 . G <*> 0 . DP=27;I16=15,11,0,0,853,28887,0,0,1555,93025,0,0,393,8477,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,171:6:0 0,21,174:7:0 +X 3606 . C <*> 0 . DP=27;I16=15,12,0,0,982,36756,0,0,1615,96625,0,0,415,8967,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,187:6:0 0,27,231:9:0 +X 3607 . A <*> 0 . DP=26;I16=15,11,0,0,927,33859,0,0,1555,93025,0,0,417,9005,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,183:6:0 0,27,232:9:0 +X 3608 . A <*> 0 . DP=27;I16=14,12,0,0,930,34054,0,0,1555,93025,0,0,394,8450,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,176:6:0 0,24,232:8:0 +X 3609 . A <*> 0 . DP=27;I16=15,12,0,0,955,34701,0,0,1615,96625,0,0,421,9127,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,186:6:0 0,27,238:9:0 +X 3610 . C <*> 0 . DP=27;I16=14,12,0,0,915,33071,0,0,1555,93025,0,0,397,8537,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,172:6:0 0,24,221:8:0 +X 3611 . C <*> 0 . DP=25;I16=13,11,0,0,899,33995,0,0,1435,85825,0,0,398,8502,0,0;QS=3,0;MQSB=0.950498;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,173:6:0 0,24,234:8:0 +X 3612 . A <*> 0 . DP=25;I16=14,11,0,0,957,37723,0,0,1495,89425,0,0,424,9118,0,0;QS=3,0;MQSB=0.955682;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,194:6:0 0,27,251:9:0 +X 3613 . G <*> 0 . DP=26;I16=13,12,0,0,902,33110,0,0,1495,89425,0,0,399,8461,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,172:6:0 0,24,223:8:0 +X 3614 . T <*> 0 . DP=26;I16=14,12,0,0,912,33340,0,0,1555,93025,0,0,425,9083,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,156:6:0 0,27,237:9:0 +X 3615 . A <*> 0 . DP=26;I16=15,11,0,0,946,35138,0,0,1555,93025,0,0,427,9109,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,176:6:0 0,27,242:9:0 +X 3616 . T <*> 0 . DP=26;I16=15,11,0,0,965,36541,0,0,1555,93025,0,0,431,9163,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,185:6:0 0,27,238:9:0 +X 3617 . C <*> 0 . DP=25;I16=14,11,0,0,907,33675,0,0,1495,89425,0,0,436,9196,0,0;QS=3,0;MQSB=0.955682;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,176:6:0 0,24,215:8:0 +X 3618 . C <*> 0 . DP=25;I16=14,11,0,0,964,37698,0,0,1495,89425,0,0,441,9259,0,0;QS=3,0;MQSB=0.955682;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,190:6:0 0,24,225:8:0 +X 3619 . T <*> 0 . DP=25;I16=14,11,0,0,961,37553,0,0,1495,89425,0,0,446,9352,0,0;QS=3,0;MQSB=0.955682;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,194:6:0 0,24,238:8:0 +X 3620 . A <*> 0 . DP=25;I16=14,11,0,0,880,31656,0,0,1495,89425,0,0,451,9475,0,0;QS=3,0;MQSB=0.955682;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,178:6:0 0,24,212:8:0 +X 3621 . C <*> 0 . DP=25;I16=14,11,0,0,949,36561,0,0,1495,89425,0,0,456,9628,0,0;QS=3,0;MQSB=0.955682;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,182:6:0 0,24,230:8:0 +X 3622 . T <*> 0 . DP=26;I16=15,11,0,0,983,38067,0,0,1555,93025,0,0,460,9762,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,194:7:0 0,24,242:8:0 +X 3623 . G <*> 0 . DP=27;I16=16,11,0,0,969,35645,0,0,1615,96625,0,0,465,9929,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,195:7:0 0,24,209:8:0 +X 3624 . T <*> 0 . DP=27;I16=15,11,0,0,948,35330,0,0,1555,93025,0,0,448,9596,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,188:6:0 0,24,224:8:0 +X 3625 . G <*> 0 . DP=27;I16=14,12,0,0,983,37483,0,0,1555,93025,0,0,453,9735,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,210:7:0 0,24,219:8:0 +X 3626 . T <*> 0 . DP=28;I16=15,12,0,0,998,37364,0,0,1615,96625,0,0,458,9854,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,214:7:0 0,27,229:9:0 +X 3627 . G <*> 0 . DP=29;I16=15,13,0,0,999,36375,0,0,1675,100225,0,0,464,10004,0,0;QS=3,0;MQSB=0.956162;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,199:7:0 0,27,224:9:0 +X 3628 . T <*> 0 . DP=29;I16=15,13,0,0,1033,38721,0,0,1675,100225,0,0,471,10187,0,0;QS=3,0;MQSB=0.956162;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,206:7:0 0,27,232:9:0 +X 3629 . G <*> 0 . DP=29;I16=15,13,0,0,1058,40226,0,0,1675,100225,0,0,476,10304,0,0;QS=3,0;MQSB=0.956162;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,207:7:0 0,27,235:9:0 +X 3630 . T <*> 0 . DP=30;I16=15,14,0,0,1052,39072,0,0,1735,103825,0,0,480,10404,0,0;QS=3,0;MQSB=0.954405;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,216:7:0 0,27,223:9:0 +X 3631 . C <*> 0 . DP=29;I16=13,14,0,0,884,29476,0,0,1615,96625,0,0,461,9911,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,186:7:0 0,21,179:7:0 +X 3632 . G <*> 0 . DP=29;I16=14,14,0,0,914,31068,0,0,1675,100225,0,0,491,10649,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,183:7:0 0,24,181:8:0 +X 3633 . T <*> 0 . DP=29;I16=14,14,0,0,1022,38214,0,0,1675,100225,0,0,496,10792,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,216:7:0 0,24,222:8:0 +X 3634 . T <*> 0 . DP=29;I16=14,14,0,0,1043,39891,0,0,1675,100225,0,0,500,10914,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,219:7:0 0,24,227:8:0 +X 3635 . T <*> 0 . DP=28;I16=13,14,0,0,1029,39507,0,0,1615,96625,0,0,505,11063,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,219:7:0 0,24,224:8:0 +X 3636 . G <*> 0 . DP=28;I16=13,14,0,0,1001,37681,0,0,1615,96625,0,0,510,11238,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,201:7:0 0,24,217:8:0 +X 3637 . T <*> 0 . DP=27;I16=13,14,0,0,1019,39331,0,0,1615,96625,0,0,515,11439,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,212:7:0 0,24,240:8:0 +X 3638 . T <*> 0 . DP=26;I16=12,14,0,0,967,36467,0,0,1555,93025,0,0,520,11616,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,185:6:0 0,24,222:8:0 +X 3639 . G <*> 0 . DP=27;I16=13,14,0,0,997,37265,0,0,1615,96625,0,0,524,11768,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,183:6:0 0,27,221:9:0 +X 3640 . T <*> 0 . DP=27;I16=13,14,0,0,1001,37533,0,0,1615,96625,0,0,527,11847,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,191:6:0 0,27,229:9:0 +X 3641 . G <*> 0 . DP=27;I16=13,14,0,0,977,36379,0,0,1615,96625,0,0,529,11905,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,178:6:0 0,27,224:9:0 +X 3642 . T <*> 0 . DP=26;I16=12,13,0,0,931,35169,0,0,1495,89425,0,0,506,11314,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,169:5:0 0,24,225:8:0 +X 3643 . T <*> 0 . DP=26;I16=13,13,0,0,968,36820,0,0,1555,93025,0,0,533,11997,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,176:5:0 0,27,230:9:0 +X 3644 . T <*> 0 . DP=26;I16=12,13,0,0,961,37477,0,0,1495,89425,0,0,517,11755,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,175:5:0 0,24,236:8:0 +X 3645 . T <*> 0 . DP=26;I16=13,13,0,0,980,37508,0,0,1555,93025,0,0,537,12185,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,175:5:0 0,27,239:9:0 +X 3646 . C <*> 0 . DP=26;I16=12,13,0,0,766,25026,0,0,1495,89425,0,0,514,11690,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,33,234:11:0 0,15,136:5:0 0,27,188:9:0 +X 3647 . G <*> 0 . DP=26;I16=12,12,0,0,820,29600,0,0,1435,85825,0,0,492,11218,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,151:5:0 0,21,173:7:0 +X 3648 . A <*> 0 . DP=26;I16=13,12,0,0,924,34680,0,0,1495,89425,0,0,519,11919,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,174:5:0 0,24,225:8:0 +X 3649 . C <*> 0 . DP=26;I16=14,12,0,0,955,36105,0,0,1555,93025,0,0,545,12593,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,173:5:0 0,27,226:9:0 +X 3650 . A <*> 0 . DP=27;I16=15,12,0,0,1033,40511,0,0,1615,96625,0,0,546,12664,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,196:6:0 0,27,246:9:0 +X 3651 . G <*> 0 . DP=27;I16=15,12,0,0,1035,40351,0,0,1615,96625,0,0,547,12707,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,194:6:0 0,27,233:9:0 +X 3652 . C <*> 0 . DP=29;I16=15,13,0,0,1010,38264,0,0,1675,100225,0,0,521,12047,0,0;QS=3,0;MQSB=0.956162;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,198:6:0 0,27,225:9:0 +X 3653 . T <*> 0 . DP=29;I16=16,13,0,0,1109,42919,0,0,1735,103825,0,0,546,12610,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,202:6:0 0,27,239:9:0 +X 3654 . G <*> 0 . DP=28;I16=14,12,0,0,981,37447,0,0,1555,93025,0,0,514,11882,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,184:6:0 0,18,180:6:0 +X 3655 . T <*> 0 . DP=28;I16=16,12,0,0,999,37029,0,0,1675,100225,0,0,541,12505,0,0;QS=3,0;MQSB=0.96195;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,190:6:0 0,21,179:7:0 +X 3656 . C <*> 0 . DP=28;I16=15,12,0,0,963,35883,0,0,1615,96625,0,0,518,11848,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,164:5:0 0,21,191:7:0 +X 3657 . C <*> 0 . DP=28;I16=15,12,0,0,923,32223,0,0,1615,96625,0,0,520,11836,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,154:5:0 0,21,192:7:0 +X 3658 . G <*> 0 . DP=28;I16=15,12,0,0,876,29960,0,0,1615,96625,0,0,539,12405,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,142:5:0 0,21,163:7:0 +X 3659 . T <*> 0 . DP=28;I16=16,12,0,0,996,36682,0,0,1675,100225,0,0,548,12448,0,0;QS=3,0;MQSB=0.96195;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,163:6:0 0,21,186:7:0 +X 3660 . G <*> 0 . DP=28;I16=15,12,0,0,997,37571,0,0,1615,96625,0,0,526,11920,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,172:6:0 0,18,171:6:0 +X 3661 . T <*> 0 . DP=28;I16=16,12,0,0,1013,37837,0,0,1675,100225,0,0,549,12423,0,0;QS=3,0;MQSB=0.96195;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,180:6:0 0,21,188:7:0 +X 3662 . T <*> 0 . DP=28;I16=15,12,0,0,987,36627,0,0,1615,96625,0,0,528,11980,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,182:6:0 0,18,184:6:0 +X 3663 . A <*> 0 . DP=29;I16=16,12,0,0,997,36233,0,0,1675,100225,0,0,527,11959,0,0;QS=3,0;MQSB=0.96195;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,170:6:0 0,18,180:6:0 +X 3664 . T <*> 0 . DP=29;I16=17,12,0,0,1044,38402,0,0,1735,103825,0,0,550,12490,0,0;QS=3,0;MQSB=0.965321;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,183:6:0 0,21,196:7:0 +X 3665 . A <*> 0 . DP=27;I16=16,11,0,0,1017,38535,0,0,1615,96625,0,0,552,12510,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,182:6:0 0,21,208:7:0 +X 3666 . A <*> 0 . DP=27;I16=16,11,0,0,1036,40292,0,0,1615,96625,0,0,554,12550,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,193:6:0 0,21,208:7:0 +X 3667 . T <*> 0 . DP=27;I16=15,11,0,0,955,35895,0,0,1555,93025,0,0,540,12354,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,189:6:0 0,18,189:6:0 +X 3668 . A <*> 0 . DP=27;I16=16,11,0,0,981,36297,0,0,1615,96625,0,0,557,12641,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,182:6:0 0,21,209:7:0 +X 3669 . A <*> 0 . DP=27;I16=16,11,0,0,1030,39666,0,0,1615,96625,0,0,558,12694,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,194:6:0 0,21,209:7:0 +X 3670 . T <*> 0 . DP=28;I16=17,11,0,0,1057,40245,0,0,1675,100225,0,0,559,12769,0,0;QS=3,0;MQSB=0.967085;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,181:6:0 0,24,220:8:0 +X 3671 . T <*> 0 . DP=28;I16=17,11,0,0,1059,40427,0,0,1675,100225,0,0,561,12867,0,0;QS=3,0;MQSB=0.967085;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,193:6:0 0,24,223:8:0 +X 3672 . C <*> 0 . DP=28;I16=16,11,0,0,988,37264,0,0,1615,96625,0,0,550,12820,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,169:6:0 0,21,205:7:0 +X 3673 . C <*> 0 . DP=27;I16=16,10,0,0,1016,40148,0,0,1555,93025,0,0,528,12314,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,154:5:0 0,24,219:8:0 +X 3674 . T <*> 0 . DP=27;I16=17,10,0,0,1035,40645,0,0,1615,96625,0,0,556,13028,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,155:5:0 0,24,228:8:0 +X 3675 . C <*> 0 . DP=27;I16=17,10,0,0,1049,41413,0,0,1615,96625,0,0,558,13090,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,149:5:0 0,24,222:8:0 +X 3676 . T <*> 0 . DP=27;I16=17,10,0,0,1040,40640,0,0,1615,96625,0,0,559,13125,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,159:5:0 0,24,231:8:0 +X 3677 . A <*> 0 . DP=27;I16=16,10,0,0,922,34182,0,0,1555,93025,0,0,537,12557,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,136:5:0 0,24,217:8:0 +X 3678 . G <*> 0 . DP=27;I16=17,10,0,0,1009,38307,0,0,1615,96625,0,0,563,13159,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,149:5:0 0,24,216:8:0 +X 3679 . T <*> 0 . DP=27;I16=17,10,0,0,1018,39274,0,0,1615,96625,0,0,563,13105,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,156:5:0 0,24,227:8:0 +X 3680 . T <*> 0 . DP=27;I16=17,10,0,0,988,36872,0,0,1615,96625,0,0,562,13022,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,157:5:0 0,24,202:8:0 +X 3681 . C <*> 0 . DP=27;I16=17,10,0,0,1012,39154,0,0,1615,96625,0,0,560,12910,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,157:5:0 0,24,217:8:0 +X 3682 . A <*> 0 . DP=27;I16=17,10,0,0,1009,38221,0,0,1615,96625,0,0,557,12769,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,156:5:0 0,24,220:8:0 +X 3683 . A <*> 0 . DP=27;I16=17,9,0,0,966,36748,0,0,1555,93025,0,0,546,12552,0,0;QS=3,0;MQSB=0.971017;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,153:5:0 0,24,225:8:0 +X 3684 . A <*> 0 . DP=26;I16=16,10,0,0,974,37440,0,0,1555,93025,0,0,550,12456,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,155:5:0 0,21,215:7:0 +X 3685 . T <*> 0 . DP=26;I16=16,10,0,0,954,36330,0,0,1555,93025,0,0,547,12333,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,148:5:0 0,21,207:7:0 +X 3686 . T <*> 0 . DP=26;I16=16,10,0,0,979,37645,0,0,1555,93025,0,0,544,12232,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,162:5:0 0,21,216:7:0 +X 3687 . T <*> 0 . DP=27;I16=16,11,0,0,1028,39276,0,0,1592,94394,0,0,541,12153,0,0;QS=3,0;MQSB=0.989102;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,159:5:0 0,24,229:8:0 +X 3688 . A <*> 0 . DP=28;I16=17,10,0,0,1007,37883,0,0,1569,92163,0,0,526,11904,0,0;QS=3,0;MQSB=0.99874;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,148:5:0 0,24,232:8:0 +X 3689 . T <*> 0 . DP=28;I16=17,11,0,0,1042,39780,0,0,1629,95763,0,0,535,11919,0,0;QS=3,0;MQSB=0.995584;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,162:5:0 0,24,233:8:0 +X 3690 . T <*> 0 . DP=28;I16=17,11,0,0,1051,39981,0,0,1629,95763,0,0,532,11816,0,0;QS=3,0;MQSB=0.995584;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,160:5:0 0,24,225:8:0 +X 3691 . C <*> 0 . DP=28;I16=16,11,0,0,1037,40549,0,0,1569,92163,0,0,520,11592,0,0;QS=3,0;MQSB=0.992419;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,155:5:0 0,21,214:7:0 +X 3692 . A <*> 0 . DP=29;I16=18,11,0,0,1028,37574,0,0,1689,99363,0,0,522,11496,0,0;QS=3,0;MQSB=0.99773;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,156:5:0 0,24,209:8:0 +X 3693 . T <*> 0 . DP=28;I16=18,10,0,0,1067,40901,0,0,1629,95763,0,0,519,11381,0,0;QS=3,0;MQSB=0.999713;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,160:5:0 0,24,230:8:0 +X 3694 . T <*> 0 . DP=28;I16=18,10,0,0,1043,39659,0,0,1629,95763,0,0,516,11296,0,0;QS=3,0;MQSB=0.999713;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,159:5:0 0,24,234:8:0 +X 3695 . T <*> 0 . DP=28;I16=18,10,0,0,1046,39662,0,0,1629,95763,0,0,513,11241,0,0;QS=3,0;MQSB=0.999713;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,156:5:0 0,24,233:8:0 +X 3696 . T <*> 0 . DP=28;I16=18,10,0,0,1075,41567,0,0,1629,95763,0,0,509,11165,0,0;QS=3,0;MQSB=0.999713;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,162:5:0 0,24,235:8:0 +X 3697 . T <*> 0 . DP=28;I16=18,10,0,0,1031,38399,0,0,1629,95763,0,0,505,11117,0,0;QS=3,0;MQSB=0.999713;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,155:5:0 0,24,229:8:0 +X 3698 . A <*> 0 . DP=28;I16=18,9,0,0,983,36457,0,0,1569,92163,0,0,477,10515,0,0;QS=3,0;MQSB=0.999669;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,144:5:0 0,24,229:8:0 +X 3699 . A <*> 0 . DP=27;I16=17,10,0,0,1011,38455,0,0,1569,92163,0,0,493,10861,0,0;QS=3,0;MQSB=0.99874;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,150:5:0 0,21,226:7:0 +X 3700 . C <*> 0 . DP=28;I16=16,11,0,0,970,35910,0,0,1574,92738,0,0,473,10525,0,0;QS=3,0;MQSB=0.992419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,168:6:0 0,24,212:8:0 +X 3701 . T <*> 0 . DP=28;I16=17,11,0,0,1071,41669,0,0,1634,96338,0,0,484,10618,0,0;QS=3,0;MQSB=0.990092;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,196:6:0 0,24,233:8:0 +X 3702 . T <*> 0 . DP=28;I16=17,10,0,0,1019,38653,0,0,1597,94969,0,0,462,10144,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,184:6:0 0,21,207:7:0 +X 3703 . C <*> 0 . DP=28;I16=17,11,0,0,1059,40561,0,0,1634,96338,0,0,470,10154,0,0;QS=3,0;MQSB=0.990092;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,183:6:0 0,24,232:8:0 +X 3704 . A <*> 0 . DP=28;I16=17,10,0,0,1015,38483,0,0,1574,92738,0,0,439,9347,0,0;QS=3,0;MQSB=0.984677;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,182:6:0 0,21,211:7:0 +X 3705 . T <*> 0 . DP=27;I16=17,10,0,0,992,37112,0,0,1574,92738,0,0,459,9773,0,0;QS=3,0;MQSB=0.984677;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,180:6:0 0,21,209:7:0 +X 3706 . A <*> 0 . DP=27;I16=17,10,0,0,1040,40262,0,0,1574,92738,0,0,454,9608,0,0;QS=3,0;MQSB=0.984677;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,186:6:0 0,21,204:7:0 +X 3707 . G <*> 0 . DP=26;I16=17,9,0,0,974,37394,0,0,1514,89138,0,0,450,9476,0,0;QS=3,0;MQSB=0.977029;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,173:6:0 0,18,168:6:0 +X 3708 . T <*> 0 . DP=26;I16=18,7,0,0,911,33609,0,0,1454,85538,0,0,426,8934,0,0;QS=3,0;MQSB=0.914166;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,182:6:0 0,15,139:5:0 +X 3709 . A <*> 0 . DP=26;I16=18,8,0,0,905,32473,0,0,1491,86907,0,0,445,9305,0,0;QS=3,0;MQSB=0.998458;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,168:6:0 0,18,162:6:0 +X 3710 . C <*> 0 . DP=26;I16=18,8,0,0,924,33504,0,0,1491,86907,0,0,443,9267,0,0;QS=3,0;MQSB=0.998458;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,165:6:0 0,18,159:6:0 +X 3711 . C <*> 0 . DP=26;I16=18,8,0,0,953,35965,0,0,1491,86907,0,0,441,9261,0,0;QS=3,0;MQSB=0.998458;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,164:6:0 0,18,173:6:0 +X 3712 . A <*> 0 . DP=26;I16=18,8,0,0,893,31917,0,0,1491,86907,0,0,439,9287,0,0;QS=3,0;MQSB=0.998458;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,144:6:0 0,18,165:6:0 +X 3713 . C <*> 0 . DP=26;I16=19,7,0,0,908,32834,0,0,1491,86907,0,0,437,9293,0,0;QS=3,0;MQSB=0.989612;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,163:6:0 0,18,164:6:0 +X 3714 . A <*> 0 . DP=27;I16=19,6,0,0,920,34366,0,0,1408,81076,0,0,409,8651,0,0;QS=3,0;MQSB=0.999494;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,177:6:0 0,18,174:6:0 +X 3715 . T <*> 0 . DP=28;I16=21,6,0,0,982,36286,0,0,1505,86045,0,0,408,8616,0,0;QS=3,0;MQSB=0.996181;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,180:6:0 0,18,164:6:0 +X 3716 . T <*> 0 . DP=26;I16=19,7,0,0,927,33833,0,0,1445,82445,0,0,434,9236,0,0;QS=3,0;MQSB=0.966731;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,165:5:0 0,18,164:6:0 +X 3717 . C <*> 0 . DP=26;I16=19,7,0,0,979,37527,0,0,1445,82445,0,0,435,9261,0,0;QS=3,0;MQSB=0.966731;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,165:5:0 0,18,168:6:0 +X 3718 . T <*> 0 . DP=26;I16=19,7,0,0,994,39040,0,0,1445,82445,0,0,435,9265,0,0;QS=3,0;MQSB=0.966731;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,169:5:0 0,18,165:6:0 +X 3719 . A <*> 0 . DP=26;I16=19,6,0,0,889,32163,0,0,1408,81076,0,0,410,8672,0,0;QS=3,0;MQSB=0.747144;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,148:5:0 0,15,142:5:0 +X 3720 . C <*> 0 . DP=26;I16=19,7,0,0,934,34326,0,0,1445,82445,0,0,435,9357,0,0;QS=3,0;MQSB=0.966731;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,148:5:0 0,18,158:6:0 +X 3721 . A <*> 0 . DP=27;I16=20,5,0,0,910,33944,0,0,1405,80725,0,0,385,8195,0,0;QS=3,0;MQSB=0.697274;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,153:5:0 0,15,145:5:0 +X 3722 . C <*> 0 . DP=27;I16=20,7,0,0,964,35276,0,0,1502,85694,0,0,436,9562,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,151:5:0 0,18,165:6:0 +X 3723 . A <*> 0 . DP=25;I16=18,6,0,0,888,33516,0,0,1345,77125,0,0,414,9082,0,0;QS=3,0;MQSB=0.606531;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,134:4:0 0,15,145:5:0 +X 3724 . C <*> 0 . DP=25;I16=18,7,0,0,944,35956,0,0,1382,78494,0,0,442,9878,0,0;QS=3,0;MQSB=0.889393;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,137:4:0 0,18,169:6:0 +X 3725 . T <*> 0 . DP=25;I16=18,7,0,0,973,38263,0,0,1382,78494,0,0,445,10075,0,0;QS=3,0;MQSB=0.889393;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,138:4:0 0,18,190:6:0 +X 3726 . G <*> 0 . DP=24;I16=18,6,0,0,865,32339,0,0,1322,74894,0,0,446,10146,0,0;QS=3,0;MQSB=0.934987;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,93:3:0 0,18,166:6:0 +X 3727 . C <*> 0 . DP=22;I16=17,5,0,0,762,27812,0,0,1202,67694,0,0,447,10139,0,0;QS=3,0;MQSB=0.963102;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,82:3:0 0,15,143:5:0 +X 3728 . C <*> 0 . DP=22;I16=17,5,0,0,792,29850,0,0,1202,67694,0,0,448,10154,0,0;QS=3,0;MQSB=0.963102;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,89:3:0 0,15,160:5:0 +X 3729 . C <*> 0 . DP=22;I16=17,5,0,0,838,32312,0,0,1202,67694,0,0,449,10191,0,0;QS=3,0;MQSB=0.963102;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,93:3:0 0,15,164:5:0 +X 3730 . A <*> 0 . DP=21;I16=17,4,0,0,749,27561,0,0,1142,64094,0,0,448,10100,0,0;QS=3,0;MQSB=0.995997;MQ0F=0 PL:DP:DV 0,39,241:13:0 0,9,98:3:0 0,15,159:5:0 +X 3731 . T <*> 0 . DP=22;I16=18,4,0,0,787,29489,0,0,1152,64194,0,0,447,10031,0,0;QS=3,0;MQSB=0.967917;MQ0F=0 PL:DP:DV 0,42,253:14:0 0,9,101:3:0 0,15,139:5:0 +X 3732 . G <*> 0 . DP=22;I16=18,4,0,0,811,30695,0,0,1152,64194,0,0,447,9985,0,0;QS=3,0;MQSB=0.967917;MQ0F=0 PL:DP:DV 0,42,252:14:0 0,9,101:3:0 0,15,149:5:0 +X 3733 . T <*> 0 . DP=23;I16=19,4,0,0,820,29616,0,0,1212,67794,0,0,447,9963,0,0;QS=3,0;MQSB=0.979651;MQ0F=0 PL:DP:DV 0,45,248:15:0 0,9,101:3:0 0,15,152:5:0 +X 3734 . C <*> 0 . DP=24;I16=20,4,0,0,863,32277,0,0,1272,71394,0,0,447,9915,0,0;QS=3,0;MQSB=0.988072;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,86:3:0 0,15,152:5:0 +X 3735 . C <*> 0 . DP=24;I16=20,4,0,0,826,30112,0,0,1272,71394,0,0,448,9892,0,0;QS=3,0;MQSB=0.988072;MQ0F=0 PL:DP:DV 0,48,254:16:0 0,9,83:3:0 0,15,152:5:0 +X 3736 . C <*> 0 . DP=25;I16=20,3,0,0,839,31471,0,0,1262,71294,0,0,419,9245,0,0;QS=3,0;MQSB=0.963194;MQ0F=0 PL:DP:DV 0,42,235:14:0 0,9,99:3:0 0,18,156:6:0 +X 3737 . C <*> 0 . DP=25;I16=21,4,0,0,894,33402,0,0,1332,74994,0,0,451,9925,0,0;QS=3,0;MQSB=0.993838;MQ0F=0 PL:DP:DV 0,48,251:16:0 0,9,95:3:0 0,18,175:6:0 +X 3738 . T <*> 0 . DP=25;I16=21,4,0,0,926,35484,0,0,1332,74994,0,0,452,9934,0,0;QS=3,0;MQSB=0.993838;MQ0F=0 PL:DP:DV 0,48,253:16:0 0,9,101:3:0 0,18,189:6:0 +X 3739 . C <*> 0 . DP=25;I16=21,4,0,0,958,37390,0,0,1332,74994,0,0,452,9922,0,0;QS=3,0;MQSB=0.993838;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,105:3:0 0,18,181:6:0 +X 3740 . A <*> 0 . DP=24;I16=20,4,0,0,848,31126,0,0,1272,71394,0,0,452,9886,0,0;QS=3,0;MQSB=0.988072;MQ0F=0 PL:DP:DV 0,48,247:16:0 0,9,109:3:0 0,15,163:5:0 +X 3741 . A <*> 0 . DP=24;I16=19,4,0,0,814,30176,0,0,1212,67794,0,0,442,9742,0,0;QS=3,0;MQSB=0.979651;MQ0F=0 PL:DP:DV 0,48,238:16:0 0,6,82:2:0 0,15,172:5:0 +X 3742 . G <*> 0 . DP=24;I16=20,4,0,0,893,34371,0,0,1272,71394,0,0,450,9782,0,0;QS=3,0;MQSB=0.988072;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,101:3:0 0,15,162:5:0 +X 3743 . C <*> 0 . DP=24;I16=19,4,0,0,839,31673,0,0,1262,71294,0,0,437,9619,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,254:15:0 0,9,103:3:0 0,15,158:5:0 +X 3744 . T <*> 0 . DP=24;I16=20,4,0,0,918,36126,0,0,1272,71394,0,0,448,9766,0,0;QS=3,0;MQSB=0.988072;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,118:3:0 0,15,164:5:0 +X 3745 . T <*> 0 . DP=24;I16=19,4,0,0,808,29490,0,0,1212,67794,0,0,422,9166,0,0;QS=3,0;MQSB=0.979651;MQ0F=0 PL:DP:DV 0,45,233:15:0 0,9,108:3:0 0,15,158:5:0 +X 3746 . C <*> 0 . DP=24;I16=20,4,0,0,886,33564,0,0,1272,71394,0,0,445,9789,0,0;QS=3,0;MQSB=0.988072;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,101:3:0 0,15,165:5:0 +X 3747 . C <*> 0 . DP=24;I16=19,4,0,0,833,31071,0,0,1262,71294,0,0,426,9504,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,249:15:0 0,9,103:3:0 0,15,162:5:0 +X 3748 . C <*> 0 . DP=24;I16=19,4,0,0,845,31753,0,0,1262,71294,0,0,422,9464,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,106:3:0 0,15,161:5:0 +X 3749 . C <*> 0 . DP=24;I16=19,4,0,0,844,31888,0,0,1262,71294,0,0,417,9395,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,250:15:0 0,9,111:3:0 0,15,154:5:0 +X 3750 . T <*> 0 . DP=25;I16=21,4,0,0,876,32880,0,0,1309,72763,0,0,431,9709,0,0;QS=3,0;MQSB=0.966906;MQ0F=0 PL:DP:DV 0,51,251:17:0 0,9,112:3:0 0,15,146:5:0 +X 3751 . G <*> 0 . DP=24;I16=19,4,0,0,836,31374,0,0,1239,69063,0,0,408,9274,0,0;QS=3,0;MQSB=0.986928;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,82:2:0 0,15,162:5:0 +X 3752 . G <*> 0 . DP=22;I16=19,2,0,0,728,26270,0,0,1069,58363,0,0,404,9134,0,0;QS=3,0;MQSB=0.868421;MQ0F=0 PL:DP:DV 0,42,182:14:0 0,6,74:2:0 0,15,159:5:0 +X 3753 . C <*> 0 . DP=22;I16=19,3,0,0,761,28017,0,0,1129,61963,0,0,426,9674,0,0;QS=3,0;MQSB=0.995434;MQ0F=0 PL:DP:DV 0,45,213:15:0 0,6,61:2:0 0,15,163:5:0 +X 3754 . T <*> 0 . DP=23;I16=19,3,0,0,767,28751,0,0,1129,61963,0,0,425,9707,0,0;QS=3,0;MQSB=0.995434;MQ0F=0 PL:DP:DV 0,45,218:15:0 0,6,69:2:0 0,15,157:5:0 +X 3755 . C <*> 0 . DP=21;I16=16,4,0,0,749,28747,0,0,1028,55504,0,0,404,9188,0,0;QS=3,0;MQSB=0.777932;MQ0F=0 PL:DP:DV 0,36,219:12:0 0,9,93:3:0 0,15,161:5:0 +X 3756 . C <*> 0 . DP=22;I16=17,4,0,0,782,29994,0,0,1038,55604,0,0,430,9840,0,0;QS=3,0;MQSB=0.885747;MQ0F=0 PL:DP:DV 0,39,229:13:0 0,9,93:3:0 0,15,159:5:0 +X 3757 . T <*> 0 . DP=23;I16=17,6,0,0,828,30942,0,0,1158,62804,0,0,456,10510,0,0;QS=3,0;MQSB=0.9945;MQ0F=0 PL:DP:DV 0,39,210:13:0 0,15,143:5:0 0,15,169:5:0 +X 3758 . G <*> 0 . DP=23;I16=17,6,0,0,832,30792,0,0,1158,62804,0,0,458,10574,0,0;QS=3,0;MQSB=0.9945;MQ0F=0 PL:DP:DV 0,39,220:13:0 0,15,135:5:0 0,15,147:5:0 +X 3759 . C <*> 0 . DP=23;I16=17,4,0,0,756,28338,0,0,1061,57835,0,0,409,9357,0,0;QS=3,0;MQSB=0.964547;MQ0F=0 PL:DP:DV 0,39,220:13:0 0,12,112:4:0 0,12,127:4:0 +X 3760 . A <*> 0 . DP=24;I16=17,7,0,0,792,27956,0,0,1218,66404,0,0,459,10607,0,0;QS=3,0;MQSB=0.95083;MQ0F=0 PL:DP:DV 0,39,203:13:0 0,15,127:5:0 0,18,180:6:0 +X 3761 . A <*> 0 . DP=24;I16=17,7,0,0,871,32185,0,0,1218,66404,0,0,460,10624,0,0;QS=3,0;MQSB=0.95083;MQ0F=0 PL:DP:DV 0,39,215:13:0 0,15,136:5:0 0,18,188:6:0 +X 3762 . C <*> 0 . DP=25;I16=17,7,0,0,831,29665,0,0,1241,68635,0,0,435,9983,0,0;QS=3,0;MQSB=0.69242;MQ0F=0 PL:DP:DV 0,39,209:13:0 0,18,149:6:0 0,15,159:5:0 +X 3763 . C <*> 0 . DP=24;I16=16,8,0,0,837,30619,0,0,1218,66404,0,0,460,10510,0,0;QS=3,0;MQSB=0.844324;MQ0F=0 PL:DP:DV 0,36,213:12:0 0,18,149:6:0 0,18,186:6:0 +X 3764 . A <*> 0 . DP=25;I16=17,7,0,0,856,31506,0,0,1241,68635,0,0,437,9903,0,0;QS=3,0;MQSB=0.69242;MQ0F=0 PL:DP:DV 0,39,212:13:0 0,18,139:6:0 0,15,167:5:0 +X 3765 . C <*> 0 . DP=25;I16=17,7,0,0,845,31099,0,0,1218,66404,0,0,436,9750,0,0;QS=3,0;MQSB=0.95083;MQ0F=0 PL:DP:DV 0,39,200:13:0 0,15,129:5:0 0,18,189:6:0 +X 3766 . A <*> 0 . DP=26;I16=17,9,0,0,953,35331,0,0,1338,73604,0,0,462,10340,0,0;QS=3,0;MQSB=0.811273;MQ0F=0 PL:DP:DV 0,42,248:14:0 0,18,158:6:0 0,18,191:6:0 +X 3767 . A <*> 0 . DP=26;I16=17,9,0,0,924,33656,0,0,1338,73604,0,0,464,10328,0,0;QS=3,0;MQSB=0.811273;MQ0F=0 PL:DP:DV 0,42,246:14:0 0,18,148:6:0 0,18,191:6:0 +X 3768 . A <*> 0 . DP=26;I16=17,9,0,0,922,33842,0,0,1338,73604,0,0,466,10340,0,0;QS=3,0;MQSB=0.811273;MQ0F=0 PL:DP:DV 0,42,237:14:0 0,18,146:6:0 0,18,195:6:0 +X 3769 . T <*> 0 . DP=26;I16=17,8,0,0,891,32735,0,0,1278,70004,0,0,461,10327,0,0;QS=3,0;MQSB=0.884621;MQ0F=0 PL:DP:DV 0,42,246:14:0 0,15,144:5:0 0,18,191:6:0 +X 3770 . C <*> 0 . DP=26;I16=17,9,0,0,923,34049,0,0,1338,73604,0,0,470,10436,0,0;QS=3,0;MQSB=0.811273;MQ0F=0 PL:DP:DV 0,42,252:14:0 0,18,142:6:0 0,18,180:6:0 +X 3771 . T <*> 0 . DP=25;I16=16,8,0,0,852,31694,0,0,1218,66404,0,0,464,10438,0,0;QS=3,0;MQSB=0.844324;MQ0F=0 PL:DP:DV 0,42,253:14:0 0,15,140:5:0 0,15,157:5:0 +X 3772 . A <*> 0 . DP=26;I16=16,10,0,0,836,28434,0,0,1338,73604,0,0,476,10624,0,0;QS=3,0;MQSB=0.685145;MQ0F=0 PL:DP:DV 0,42,236:14:0 0,18,122:6:0 0,18,160:6:0 +X 3773 . C <*> 0 . DP=26;I16=16,10,0,0,893,31801,0,0,1338,73604,0,0,480,10752,0,0;QS=3,0;MQSB=0.685145;MQ0F=0 PL:DP:DV 0,42,253:14:0 0,18,140:6:0 0,18,171:6:0 +X 3774 . T <*> 0 . DP=25;I16=15,10,0,0,895,33455,0,0,1278,70004,0,0,485,10903,0,0;QS=3,0;MQSB=0.624282;MQ0F=0 PL:DP:DV 0,42,253:14:0 0,18,129:6:0 0,15,178:5:0 +X 3775 . C <*> 0 . DP=25;I16=15,9,0,0,855,31825,0,0,1241,68635,0,0,477,10883,0,0;QS=3,0;MQSB=0.439649;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,147:6:0 0,12,143:4:0 +X 3776 . T <*> 0 . DP=24;I16=15,7,0,0,838,32738,0,0,1152,64194,0,0,457,10375,0,0;QS=3,0;MQSB=0.225079;MQ0F=0 PL:DP:DV 0,39,229:13:0 0,15,149:5:0 0,12,152:4:0 +X 3777 . C <*> 0 . DP=24;I16=15,9,0,0,864,32180,0,0,1218,66404,0,0,492,10998,0,0;QS=3,0;MQSB=0.705785;MQ0F=0 PL:DP:DV 0,39,220:13:0 0,18,160:6:0 0,15,168:5:0 +X 3778 . T <*> 0 . DP=24;I16=14,9,0,0,859,32957,0,0,1208,66304,0,0,468,10372,0,0;QS=3,0;MQSB=0.836049;MQ0F=0 PL:DP:DV 0,36,227:12:0 0,18,157:6:0 0,15,167:5:0 +X 3779 . G <*> 0 . DP=24;I16=15,9,0,0,844,31206,0,0,1218,66404,0,0,493,10971,0,0;QS=3,0;MQSB=0.705785;MQ0F=0 PL:DP:DV 0,39,220:13:0 0,18,152:6:0 0,15,167:5:0 +X 3780 . C <*> 0 . DP=25;I16=14,10,0,0,829,29949,0,0,1268,69904,0,0,467,10295,0,0;QS=3,0;MQSB=0.765017;MQ0F=0 PL:DP:DV 0,39,235:13:0 0,18,144:6:0 0,15,169:5:0 +X 3781 . C <*> 0 . DP=26;I16=16,10,0,0,939,34725,0,0,1315,71373,0,0,492,10896,0,0;QS=3,0;MQSB=0.541994;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,139:6:0 0,15,175:5:0 +X 3782 . T <*> 0 . DP=26;I16=16,10,0,0,989,38031,0,0,1315,71373,0,0,493,10901,0,0;QS=3,0;MQSB=0.541994;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,169:6:0 0,15,176:5:0 +X 3783 . C <*> 0 . DP=26;I16=16,10,0,0,941,34801,0,0,1315,71373,0,0,492,10836,0,0;QS=3,0;MQSB=0.541994;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,155:6:0 0,15,162:5:0 +X 3784 . T <*> 0 . DP=27;I16=16,11,0,0,1001,38035,0,0,1375,74973,0,0,491,10801,0,0;QS=3,0;MQSB=0.467219;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,155:6:0 0,15,178:5:0 +X 3785 . G <*> 0 . DP=28;I16=15,10,0,0,922,36426,0,0,1305,71273,0,0,450,9916,0,0;QS=3,0;MQSB=0.674458;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,125:5:0 0,15,179:5:0 +X 3786 . T <*> 0 . DP=28;I16=16,11,0,0,935,35697,0,0,1375,74973,0,0,490,10774,0,0;QS=3,0;MQSB=0.467219;MQ0F=0 PL:DP:DV 0,48,250:16:0 0,18,145:6:0 0,15,186:5:0 +X 3787 . G <*> 0 . DP=28;I16=16,11,0,0,963,37951,0,0,1375,74973,0,0,489,10781,0,0;QS=3,0;MQSB=0.467219;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,143:6:0 0,15,177:5:0 +X 3788 . G <*> 0 . DP=26;I16=14,9,0,0,849,33683,0,0,1184,65386,0,0,459,10075,0,0;QS=3,0;MQSB=0.525788;MQ0F=0 PL:DP:DV 0,39,239:13:0 0,18,144:6:0 0,12,161:4:0 +X 3789 . G <*> 0 . DP=26;I16=13,10,0,0,807,31019,0,0,1231,68535,0,0,438,9474,0,0;QS=3,0;MQSB=0.445672;MQ0F=0 PL:DP:DV 0,39,251:13:0 0,18,133:6:0 0,12,161:4:0 +X 3790 . T <*> 0 . DP=26;I16=13,10,0,0,829,32293,0,0,1231,68535,0,0,435,9359,0,0;QS=3,0;MQSB=0.445672;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,150:6:0 0,12,159:4:0 +X 3791 . T <*> 0 . DP=26;I16=15,10,0,0,887,34725,0,0,1301,72235,0,0,478,10336,0,0;QS=3,0;MQSB=0.382304;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,136:6:0 0,12,159:4:0 +X 3792 . G A,<*> 0 . DP=26;I16=14,8,1,0,809,32805,38,1444,1175,66425,37,1369,417,8991,22,484;QS=2.92629,0.0737052,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.195278;BQB=1;MQ0F=0 PL:DP:DV 0,8,238,42,241,255:15:1 0,12,109,12,109,109:4:0 0,12,157,12,157,157:4:0 +X 3793 . A <*> 0 . DP=26;I16=15,8,0,0,833,33775,0,0,1212,67794,0,0,435,9363,0,0;QS=3,0;MQSB=0.195278;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,93:4:0 0,12,159:4:0 +X 3794 . C <*> 0 . DP=26;I16=15,9,0,0,845,33023,0,0,1241,68635,0,0,438,9324,0,0;QS=3,0;MQSB=0.439649;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,120:5:0 0,12,157:4:0 +X 3795 . C <*> 0 . DP=26;I16=14,9,0,0,865,35649,0,0,1231,68535,0,0,408,8622,0,0;QS=3,0;MQSB=0.563599;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,132:5:0 0,12,161:4:0 +X 3796 . T <*> 0 . DP=27;I16=15,11,0,0,964,38998,0,0,1361,75835,0,0,453,9821,0,0;QS=3,0;MQSB=0.334895;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,149:7:0 0,12,164:4:0 +X 3797 . A <*> 0 . DP=27;I16=15,10,0,0,848,32392,0,0,1301,72235,0,0,424,9172,0,0;QS=3,0;MQSB=0.382304;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,124:6:0 0,12,159:4:0 +X 3798 . T <*> 0 . DP=27;I16=14,11,0,0,921,37161,0,0,1301,72235,0,0,430,9554,0,0;QS=3,0;MQSB=0.283586;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,148:7:0 0,12,165:4:0 +X 3799 . T <*> 0 . DP=27;I16=15,11,0,0,913,35929,0,0,1361,75835,0,0,439,9729,0,0;QS=3,0;MQSB=0.334895;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,150:7:0 0,12,161:4:0 +X 3800 . C <*> 0 . DP=26;I16=13,10,0,0,866,36182,0,0,1181,65035,0,0,406,9092,0,0;QS=3,0;MQSB=0.272532;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,104:5:0 0,12,161:4:0 +X 3801 . T <*> 0 . DP=23;I16=12,10,0,0,804,33600,0,0,1121,61435,0,0,430,9750,0,0;QS=3,0;MQSB=0.217267;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,99:5:0 0,9,133:3:0 +X 3802 . G <*> 0 . DP=22;I16=10,9,0,0,730,30516,0,0,994,54486,0,0,380,8550,0,0;QS=3,0;MQSB=0.472367;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,106:4:0 0,9,130:3:0 +X 3803 . G <*> 0 . DP=22;I16=11,9,0,0,703,27393,0,0,1051,57735,0,0,405,9241,0,0;QS=3,0;MQSB=0.372419;MQ0F=0 PL:DP:DV 0,39,249:13:0 0,12,92:4:0 0,9,129:3:0 +X 3804 . A <*> 0 . DP=22;I16=11,9,0,0,740,30360,0,0,1051,57735,0,0,404,9274,0,0;QS=3,0;MQSB=0.372419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,98:4:0 0,9,132:3:0 +X 3805 . C <*> 0 . DP=22;I16=12,9,0,0,737,29243,0,0,1061,57835,0,0,428,9950,0,0;QS=3,0;MQSB=0.262932;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,81:4:0 0,9,130:3:0 +X 3806 . A <*> 0 . DP=22;I16=12,9,0,0,798,32550,0,0,1061,57835,0,0,426,9968,0,0;QS=3,0;MQSB=0.262932;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,105:4:0 0,9,128:3:0 +X 3807 . C <*> 0 . DP=22;I16=10,9,0,0,664,25304,0,0,994,54486,0,0,377,8885,0,0;QS=3,0;MQSB=0.472367;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,83:4:0 0,9,115:3:0 +X 3808 . G <*> 0 . DP=21;I16=9,9,0,0,653,25297,0,0,957,53117,0,0,375,8873,0,0;QS=3,0;MQSB=0.597145;MQ0F=0 PL:DP:DV 0,33,233:11:0 0,12,109:4:0 0,9,132:3:0 +X 3809 . T <*> 0 . DP=22;I16=11,10,0,0,779,32151,0,0,1084,60066,0,0,416,9810,0,0;QS=3,0;MQSB=0.285029;MQ0F=0 PL:DP:DV 0,39,249:13:0 0,12,115:4:0 0,12,161:4:0 +X 3810 . C <*> 0 . DP=23;I16=9,11,0,0,811,34815,0,0,1077,60317,0,0,369,8739,0,0;QS=3,0;MQSB=0.499893;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,112:4:0 0,12,153:4:0 +X 3811 . A C,<*> 0 . DP=23;I16=9,11,2,0,777,32631,39,785,1077,60317,67,3349,367,8669,42,914;QS=2.94104,0.0589569,0;VDB=0.18;SGB=0.346553;RPB=0.425;MQB=0.25;MQSB=0.246128;BQB=0.025;MQ0F=0 PL:DP:DV 0,15,248,36,254,255:14:2 0,12,116,12,116,116:4:0 0,12,158,12,158,158:4:0 +X 3812 . T <*> 0 . DP=23;I16=10,11,0,0,802,32860,0,0,1084,60066,0,0,405,9447,0,0;QS=3,0;MQSB=0.187115;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,114:4:0 0,12,160:4:0 +X 3813 . A <*> 0 . DP=22;I16=10,11,0,0,815,35077,0,0,1084,60066,0,0,402,9330,0,0;QS=3,0;MQSB=0.187115;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,119:4:0 0,12,170:4:0 +X 3814 . G <*> 0 . DP=21;I16=8,11,0,0,775,33731,0,0,1037,58597,0,0,375,8605,0,0;QS=3,0;MQSB=0.41781;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,113:4:0 0,12,163:4:0 +X 3815 . A <*> 0 . DP=20;I16=8,11,0,0,708,29130,0,0,1010,57328,0,0,397,9049,0,0;QS=3,0;MQSB=0.373354;MQ0F=0 PL:DP:DV 0,33,239:11:0 0,12,110:4:0 0,12,162:4:0 +X 3816 . A <*> 0 . DP=20;I16=8,11,0,0,729,31027,0,0,1010,57328,0,0,395,8933,0,0;QS=3,0;MQSB=0.373354;MQ0F=0 PL:DP:DV 0,33,248:11:0 0,12,104:4:0 0,12,160:4:0 +X 3817 . A <*> 0 . DP=20;I16=8,11,0,0,752,31580,0,0,1010,57328,0,0,393,8833,0,0;QS=3,0;MQSB=0.373354;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,110:4:0 0,12,161:4:0 +X 3818 . T <*> 0 . DP=20;I16=8,11,0,0,728,30466,0,0,1010,57328,0,0,391,8749,0,0;QS=3,0;MQSB=0.373354;MQ0F=0 PL:DP:DV 0,33,252:11:0 0,12,115:4:0 0,12,160:4:0 +X 3819 . A <*> 0 . DP=21;I16=9,11,0,0,790,34094,0,0,1039,58169,0,0,389,8681,0,0;QS=3,0;MQSB=0.247381;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,121:4:0 0,12,167:4:0 +X 3820 . G <*> 0 . DP=21;I16=9,11,0,0,788,33636,0,0,1039,58169,0,0,388,8630,0,0;QS=3,0;MQSB=0.247381;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,112:4:0 0,12,157:4:0 +X 3821 . A <*> 0 . DP=22;I16=10,11,0,0,832,35864,0,0,1099,61769,0,0,387,8597,0,0;QS=3,0;MQSB=0.317882;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,115:4:0 0,12,168:4:0 +X 3822 . G <*> 0 . DP=22;I16=10,11,0,0,810,33228,0,0,1099,61769,0,0,386,8532,0,0;QS=3,0;MQSB=0.317882;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,103:4:0 0,12,157:4:0 +X 3823 . T <*> 0 . DP=22;I16=9,11,0,0,753,30705,0,0,1042,58520,0,0,380,8460,0,0;QS=3,0;MQSB=0.434285;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,102:4:0 0,12,163:4:0 +X 3824 . C <*> 0 . DP=22;I16=10,11,0,0,802,32368,0,0,1099,61769,0,0,384,8456,0,0;QS=3,0;MQSB=0.317882;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,105:4:0 0,12,159:4:0 +X 3825 . C <*> 0 . DP=23;I16=10,11,0,0,813,33955,0,0,1079,59889,0,0,379,8387,0,0;QS=3,0;MQSB=0.317882;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,130:5:0 0,12,157:4:0 +X 3826 . T <*> 0 . DP=23;I16=11,11,0,0,827,34611,0,0,1136,63138,0,0,381,8357,0,0;QS=3,0;MQSB=0.232836;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,133:5:0 0,12,155:4:0 +X 3827 . G <*> 0 . DP=23;I16=11,10,0,0,820,34130,0,0,1076,59538,0,0,355,7715,0,0;QS=3,0;MQSB=0.269397;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,121:4:0 0,12,162:4:0 +X 3828 . C <*> 0 . DP=23;I16=11,10,0,0,805,33147,0,0,1076,59538,0,0,354,7720,0,0;QS=3,0;MQSB=0.269397;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,114:4:0 0,12,157:4:0 +X 3829 . A <*> 0 . DP=22;I16=9,11,0,0,763,31295,0,0,1069,59789,0,0,369,8241,0,0;QS=3,0;MQSB=0.477679;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,132:5:0 0,12,158:4:0 +X 3830 . A <*> 0 . DP=23;I16=11,11,0,0,825,32693,0,0,1136,63138,0,0,377,8321,0,0;QS=3,0;MQSB=0.232836;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,143:5:0 0,12,150:4:0 +X 3831 . C A,<*> 0 . DP=23;I16=10,11,1,0,802,32198,14,196,1126,63038,10,100,370,8294,7,49;QS=2.97758,0.0224215,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.232836;BQB=1;MQ0F=0 PL:DP:DV 0,27,255,36,255,255:13:1 0,15,134,15,134,134:5:0 0,12,149,12,149,149:4:0 +X 3832 . A <*> 0 . DP=24;I16=12,11,0,0,836,32436,0,0,1196,66738,0,0,377,8389,0,0;QS=3,0;MQSB=0.291845;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,136:5:0 0,12,139:4:0 +X 3833 . C <*> 0 . DP=23;I16=10,11,0,0,690,24938,0,0,1076,59538,0,0,377,8409,0,0;QS=3,0;MQSB=0.175325;MQ0F=0 PL:DP:DV 0,36,249:12:0 0,15,113:5:0 0,12,131:4:0 +X 3834 . G <*> 0 . DP=22;I16=9,10,0,0,684,26250,0,0,1037,58597,0,0,357,8079,0,0;QS=3,0;MQSB=0.124514;MQ0F=0 PL:DP:DV 0,33,242:11:0 0,12,122:4:0 0,12,156:4:0 +X 3835 . T <*> 0 . DP=22;I16=10,11,0,0,773,30373,0,0,1076,59538,0,0,381,8475,0,0;QS=3,0;MQSB=0.175325;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,140:5:0 0,12,153:4:0 +X 3836 . G C,<*> 0 . DP=24;I16=10,12,1,0,833,33183,14,196,1132,61648,10,100,378,8412,2,4;QS=2.97647,0.0235294,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.251407;BQB=1;MQ0F=0 PL:DP:DV 0,27,255,36,255,255:13:1 0,15,149,15,149,149:5:0 0,15,188,15,188,188:5:0 +X 3837 . G <*> 0 . DP=24;I16=8,14,0,0,759,26931,0,0,1135,61999,0,0,399,8955,0,0;QS=3,0;MQSB=0.291667;MQ0F=0 PL:DP:DV 0,33,245:11:0 0,18,149:6:0 0,15,157:5:0 +X 3838 . C <*> 0 . DP=24;I16=10,14,0,0,817,28975,0,0,1202,65348,0,0,409,8945,0,0;QS=3,0;MQSB=0.122456;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,143:6:0 0,15,148:5:0 +X 3839 . C <*> 0 . DP=23;I16=9,13,0,0,688,22248,0,0,1132,61648,0,0,386,8238,0,0;QS=3,0;MQSB=0.248197;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,123:6:0 0,12,112:4:0 +X 3840 . G <*> 0 . DP=23;I16=9,14,0,0,793,27941,0,0,1192,65248,0,0,413,8809,0,0;QS=3,0;MQSB=0.211072;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,160:6:0 0,15,146:5:0 +X 3841 . T <*> 0 . DP=23;I16=9,14,0,0,867,33103,0,0,1192,65248,0,0,414,8734,0,0;QS=3,0;MQSB=0.211072;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,167:6:0 0,15,162:5:0 +X 3842 . C <*> 0 . DP=23;I16=9,14,0,0,890,34728,0,0,1192,65248,0,0,415,8689,0,0;QS=3,0;MQSB=0.211072;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,167:6:0 0,15,159:5:0 +X 3843 . T <*> 0 . DP=24;I16=9,14,0,0,896,35122,0,0,1192,65248,0,0,416,8674,0,0;QS=3,0;MQSB=0.211072;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,164:6:0 0,15,159:5:0 +X 3844 . G <*> 0 . DP=26;I16=10,16,0,0,959,35715,0,0,1372,76048,0,0,442,9314,0,0;QS=3,0;MQSB=0.220358;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,177:7:0 0,18,172:6:0 +X 3845 . T <*> 0 . DP=26;I16=10,16,0,0,970,36442,0,0,1372,76048,0,0,444,9310,0,0;QS=3,0;MQSB=0.220358;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,186:7:0 0,18,166:6:0 +X 3846 . G <*> 0 . DP=27;I16=10,17,0,0,993,37297,0,0,1432,79648,0,0,446,9338,0,0;QS=3,0;MQSB=0.195223;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,175:7:0 0,21,172:7:0 +X 3847 . T <*> 0 . DP=27;I16=10,16,0,0,952,35268,0,0,1372,76048,0,0,423,8723,0,0;QS=3,0;MQSB=0.220358;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,170:6:0 0,21,189:7:0 +X 3848 . C <*> 0 . DP=27;I16=10,17,0,0,1025,39533,0,0,1432,79648,0,0,449,9341,0,0;QS=3,0;MQSB=0.195223;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,177:7:0 0,21,188:7:0 +X 3849 . T <*> 0 . DP=27;I16=9,17,0,0,987,37685,0,0,1395,78279,0,0,450,9368,0,0;QS=3,0;MQSB=0.282527;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,179:7:0 0,21,190:7:0 +X 3850 . G <*> 0 . DP=26;I16=9,17,0,0,957,35751,0,0,1395,78279,0,0,452,9428,0,0;QS=3,0;MQSB=0.282527;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,179:7:0 0,21,182:7:0 +X 3851 . G <*> 0 . DP=26;I16=9,17,0,0,965,36475,0,0,1395,78279,0,0,453,9469,0,0;QS=3,0;MQSB=0.282527;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,177:7:0 0,21,183:7:0 +X 3852 . C <*> 0 . DP=26;I16=9,16,0,0,921,34525,0,0,1335,74679,0,0,444,9440,0,0;QS=3,0;MQSB=0.310905;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,163:6:0 0,21,179:7:0 +X 3853 . T <*> 0 . DP=28;I16=10,18,0,0,1050,40222,0,0,1484,82720,0,0,455,9641,0,0;QS=3,0;MQSB=0.515783;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,185:7:0 0,21,192:7:0 +X 3854 . T <*> 0 . DP=28;I16=10,17,0,0,955,34605,0,0,1455,81879,0,0,451,9709,0,0;QS=3,0;MQSB=0.359211;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,171:6:0 0,18,178:6:0 +X 3855 . C <*> 0 . DP=29;I16=10,18,0,0,992,36040,0,0,1515,85479,0,0,438,9264,0,0;QS=3,0;MQSB=0.331344;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,139:5:0 0,21,175:7:0 +X 3856 . T <*> 0 . DP=30;I16=10,18,0,0,1033,38725,0,0,1546,88238,0,0,464,9982,0,0;QS=3,0;MQSB=0.190183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,163:6:0 0,21,185:7:0 +X 3857 . C <*> 0 . DP=30;I16=10,19,0,0,1077,40979,0,0,1575,89079,0,0,447,9505,0,0;QS=3,0;MQSB=0.306875;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,154:5:0 0,24,194:8:0 +X 3858 . T <*> 0 . DP=31;I16=10,21,0,0,1141,42567,0,0,1695,96279,0,0,477,10255,0,0;QS=3,0;MQSB=0.266219;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,171:6:0 0,24,208:8:0 +X 3859 . C <*> 0 . DP=32;I16=10,21,0,0,950,30078,0,0,1695,96279,0,0,484,10416,0,0;QS=3,0;MQSB=0.266219;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,136:6:0 0,24,156:8:0 +X 3860 . G <*> 0 . DP=32;I16=10,22,0,0,1070,37794,0,0,1755,99879,0,0,516,11240,0,0;QS=3,0;MQSB=0.249261;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,154:6:0 0,27,209:9:0 +X 3861 . C <*> 0 . DP=33;I16=11,20,0,0,1133,42547,0,0,1672,94048,0,0,517,11391,0,0;QS=3,0;MQSB=0.19205;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,162:6:0 0,24,199:8:0 +X 3862 . T <*> 0 . DP=34;I16=11,22,0,0,1241,47443,0,0,1792,101248,0,0,526,11518,0,0;QS=3,0;MQSB=0.161533;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,185:7:0 0,27,221:9:0 +X 3863 . T <*> 0 . DP=34;I16=12,22,0,0,1200,43542,0,0,1852,104848,0,0,541,11685,0,0;QS=3,0;MQSB=0.210327;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,199:7:0 0,27,213:9:0 +X 3864 . A <*> 0 . DP=33;I16=11,22,0,0,1238,47448,0,0,1792,101248,0,0,550,11790,0,0;QS=3,0;MQSB=0.161533;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,210:7:0 0,27,230:9:0 +X 3865 . G <*> 0 . DP=34;I16=11,23,0,0,1251,47113,0,0,1852,104848,0,0,559,11933,0,0;QS=3,0;MQSB=0.149071;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,200:7:0 0,27,212:9:0 +X 3866 . C <*> 0 . DP=33;I16=11,21,0,0,1165,43545,0,0,1732,97648,0,0,545,11489,0,0;QS=3,0;MQSB=0.175751;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,189:7:0 0,24,197:8:0 +X 3867 . A <*> 0 . DP=33;I16=11,22,0,0,1152,41510,0,0,1792,101248,0,0,580,12284,0,0;QS=3,0;MQSB=0.161533;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,188:7:0 0,27,195:9:0 +X 3868 . T <*> 0 . DP=33;I16=11,22,0,0,1255,48141,0,0,1792,101248,0,0,590,12494,0,0;QS=3,0;MQSB=0.161533;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,202:7:0 0,27,221:9:0 +X 3869 . C <*> 0 . DP=33;I16=11,21,0,0,1169,43987,0,0,1732,97648,0,0,589,12623,0,0;QS=3,0;MQSB=0.175751;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,164:6:0 0,27,211:9:0 +X 3870 . T <*> 0 . DP=34;I16=11,23,0,0,1262,47808,0,0,1852,104848,0,0,608,12932,0,0;QS=3,0;MQSB=0.149071;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,215:8:0 0,27,211:9:0 +X 3871 . T <*> 0 . DP=36;I16=11,25,0,0,1341,50655,0,0,1972,112048,0,0,617,13157,0,0;QS=3,0;MQSB=0.128391;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,221:8:0 0,27,223:9:0 +X 3872 . G <*> 0 . DP=36;I16=11,25,0,0,1287,47095,0,0,1972,112048,0,0,626,13322,0,0;QS=3,0;MQSB=0.128391;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,211:8:0 0,27,200:9:0 +X 3873 . T <*> 0 . DP=35;I16=10,24,0,0,1242,46680,0,0,1852,104848,0,0,626,13428,0,0;QS=3,0;MQSB=0.0982034;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,194:7:0 0,24,212:8:0 +X 3874 . T <*> 0 . DP=36;I16=12,24,0,0,1290,47660,0,0,1972,112048,0,0,646,13774,0,0;QS=3,0;MQSB=0.182088;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,24,228:8:0 0,24,204:8:0 +X 3875 . T <*> 0 . DP=37;I16=13,24,0,0,1324,48418,0,0,2029,115297,0,0,657,14061,0,0;QS=3,0;MQSB=0.117872;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,231:8:0 0,24,197:8:0 +X 3876 . C <*> 0 . DP=37;I16=13,22,0,0,1248,45354,0,0,1909,108097,0,0,623,13325,0,0;QS=3,0;MQSB=0.140806;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,196:7:0 0,24,180:8:0 +X 3877 . C <*> 0 . DP=37;I16=13,24,0,0,1363,51201,0,0,2029,115297,0,0,681,14765,0,0;QS=3,0;MQSB=0.117872;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,217:8:0 0,24,196:8:0 +X 3878 . A <*> 0 . DP=37;I16=13,23,0,0,1309,48045,0,0,1969,111697,0,0,670,14654,0,0;QS=3,0;MQSB=0.128568;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,24,218:8:0 0,24,188:8:0 +X 3879 . A <*> 0 . DP=38;I16=14,24,0,0,1453,56567,0,0,2066,116666,0,0,703,15543,0,0;QS=3,0;MQSB=0.076112;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,226:8:0 0,24,206:8:0 +X 3880 . G <*> 0 . DP=37;I16=14,22,0,0,1311,48735,0,0,1946,109466,0,0,689,15267,0,0;QS=3,0;MQSB=0.094094;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,24,209:8:0 0,24,183:8:0 +X 3881 . G <*> 0 . DP=37;I16=14,21,0,0,1200,42778,0,0,1886,105866,0,0,690,15578,0,0;QS=3,0;MQSB=0.105399;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,18,178:6:0 0,24,174:8:0 +X 3882 . T <*> 0 . DP=37;I16=14,21,0,0,1192,42352,0,0,1886,105866,0,0,684,15348,0,0;QS=3,0;MQSB=0.105399;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,21,189:7:0 0,21,178:7:0 +X 3883 . C <*> 0 . DP=38;I16=15,22,0,0,1295,46659,0,0,2006,113066,0,0,717,16279,0,0;QS=3,0;MQSB=0.124405;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,205:8:0 0,24,171:8:0 +X 3884 . C <*> 0 . DP=39;I16=16,23,0,0,1363,49387,0,0,2103,118035,0,0,749,17141,0,0;QS=3,0;MQSB=0.0760633;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,202:8:0 0,27,212:9:0 +X 3885 . T <*> 0 . DP=40;I16=16,24,0,0,1445,53663,0,0,2163,121635,0,0,754,17262,0,0;QS=3,0;MQSB=0.0679472;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,24,219:8:0 0,27,214:9:0 +X 3886 . C <*> 0 . DP=39;I16=16,23,0,0,1370,49762,0,0,2103,118035,0,0,761,17421,0,0;QS=3,0;MQSB=0.0760633;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,24,199:8:0 0,24,191:8:0 +X 3887 . C <*> 0 . DP=39;I16=16,23,0,0,1364,49222,0,0,2103,118035,0,0,767,17567,0,0;QS=3,0;MQSB=0.0760633;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,24,194:8:0 0,24,201:8:0 +X 3888 . C <*> 0 . DP=39;I16=15,23,0,0,1387,51885,0,0,2043,114435,0,0,747,17073,0,0;QS=3,0;MQSB=0.0555905;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,195:8:0 0,24,208:8:0 +X 3889 . A <*> 0 . DP=38;I16=15,23,0,0,1364,49918,0,0,2066,116666,0,0,777,17811,0,0;QS=3,0;MQSB=0.112471;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,202:8:0 0,24,218:8:0 +X 3890 . C <*> 0 . DP=38;I16=14,23,0,0,1362,51064,0,0,2006,113066,0,0,757,17329,0,0;QS=3,0;MQSB=0.0844255;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,203:8:0 0,24,216:8:0 +X 3891 . A <*> 0 . DP=39;I16=15,24,0,0,1466,56312,0,0,2126,120266,0,0,786,18076,0,0;QS=3,0;MQSB=0.102114;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,203:8:0 0,27,239:9:0 +X 3892 . G <*> 0 . DP=38;I16=15,23,0,0,1340,48838,0,0,2066,116666,0,0,792,18226,0,0;QS=3,0;MQSB=0.112471;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,186:8:0 0,27,208:9:0 +X 3893 . T <*> 0 . DP=39;I16=15,24,0,0,1348,48170,0,0,2126,120266,0,0,798,18404,0,0;QS=3,0;MQSB=0.102114;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,196:8:0 0,27,212:9:0 +X 3894 . G <*> 0 . DP=39;I16=15,23,0,0,1364,49900,0,0,2066,116666,0,0,779,17937,0,0;QS=3,0;MQSB=0.112471;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,202:8:0 0,27,208:9:0 +X 3895 . T <*> 0 . DP=39;I16=15,24,0,0,1375,49773,0,0,2126,120266,0,0,810,18752,0,0;QS=3,0;MQSB=0.102114;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,202:8:0 0,27,225:9:0 +X 3896 . A <*> 0 . DP=40;I16=15,24,0,0,1468,57326,0,0,2126,120266,0,0,815,18923,0,0;QS=3,0;MQSB=0.102114;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,224:8:0 0,27,233:9:0 +X 3897 . G <*> 0 . DP=40;I16=15,24,0,0,1468,56812,0,0,2126,120266,0,0,819,19021,0,0;QS=3,0;MQSB=0.102114;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,21,199:7:0 0,30,234:10:0 +X 3898 . C <*> 0 . DP=40;I16=15,23,0,0,1487,59351,0,0,2066,116666,0,0,813,19023,0,0;QS=3,0;MQSB=0.112471;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,18,186:6:0 0,30,238:10:0 +X 3899 . A <*> 0 . DP=40;I16=15,24,0,0,1449,55055,0,0,2126,120266,0,0,829,19293,0,0;QS=3,0;MQSB=0.102114;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,21,191:7:0 0,30,231:10:0 +X 3900 . T <*> 0 . DP=40;I16=15,24,0,0,1458,55516,0,0,2126,120266,0,0,833,19417,0,0;QS=3,0;MQSB=0.102114;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,21,197:7:0 0,30,240:10:0 +X 3901 . G <*> 0 . DP=40;I16=14,22,0,0,1303,48245,0,0,1969,111697,0,0,761,17639,0,0;QS=3,0;MQSB=0.180757;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,18,154:6:0 0,27,218:9:0 +X 3902 . C <*> 0 . DP=40;I16=15,24,0,0,1436,55412,0,0,2126,120266,0,0,837,19537,0,0;QS=3,0;MQSB=0.102114;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,21,166:7:0 0,30,217:10:0 +X 3903 . A <*> 0 . DP=42;I16=15,24,0,0,1299,45567,0,0,2089,117417,0,0,814,19008,0,0;QS=3,0;MQSB=0.0901152;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,175:8:0 0,30,204:10:0 +X 3904 . C <*> 0 . DP=42;I16=15,24,0,0,1439,54545,0,0,2086,117066,0,0,815,19113,0,0;QS=3,0;MQSB=0.0426917;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,191:8:0 0,30,244:10:0 +X 3905 . C <*> 0 . DP=42;I16=15,25,0,0,1572,63314,0,0,2146,120666,0,0,822,19192,0,0;QS=3,0;MQSB=0.0381122;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,212:8:0 0,33,255:11:0 +X 3906 . T <*> 0 . DP=42;I16=16,25,0,0,1593,63039,0,0,2206,124266,0,0,846,19758,0,0;QS=3,0;MQSB=0.0536599;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,210:8:0 0,33,253:11:0 +X 3907 . G <*> 0 . DP=42;I16=16,25,0,0,1558,60192,0,0,2206,124266,0,0,846,19776,0,0;QS=3,0;MQSB=0.0536599;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,203:8:0 0,33,249:11:0 +X 3908 . C <*> 0 . DP=42;I16=16,25,0,0,1514,58968,0,0,2206,124266,0,0,845,19777,0,0;QS=3,0;MQSB=0.0536599;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,193:8:0 0,33,244:11:0 +X 3909 . T <*> 0 . DP=43;I16=16,25,0,0,1491,55895,0,0,2201,123691,0,0,835,19697,0,0;QS=3,0;MQSB=0.0757469;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,24,202:8:0 0,30,237:10:0 +X 3910 . A <*> 0 . DP=40;I16=16,23,0,0,1432,53926,0,0,2081,116491,0,0,844,19724,0,0;QS=3,0;MQSB=0.0949554;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,21,193:7:0 0,30,224:10:0 +X 3911 . C <*> 0 . DP=40;I16=16,23,0,0,1440,55290,0,0,2081,116491,0,0,843,19613,0,0;QS=3,0;MQSB=0.0949554;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,21,184:7:0 0,30,214:10:0 +X 3912 . A C,<*> 0 . DP=41;I16=17,22,0,1,1358,49508,16,256,2081,116491,60,3600,830,19358,11,121;QS=2.95181,0.0481928,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.125266;BQB=1;MQ0F=0 PL:DP:DV 0,69,255,69,255,255:23:0 0,21,166,21,166,166:7:0 0,14,202,27,205,208:10:1 +X 3913 . C <*> 0 . DP=40;I16=16,23,0,0,1494,59096,0,0,2081,116491,0,0,824,19100,0,0;QS=3,0;MQSB=0.0949554;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,21,183:7:0 0,30,234:10:0 +X 3914 . T <*> 0 . DP=42;I16=16,24,0,0,1512,59342,0,0,2141,120091,0,0,823,19007,0,0;QS=3,0;MQSB=0.0846181;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,21,192:7:0 0,30,228:10:0 +X 3915 . C <*> 0 . DP=42;I16=16,24,0,0,1537,60953,0,0,2141,120091,0,0,799,18321,0,0;QS=3,0;MQSB=0.0846181;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,18,176:6:0 0,30,229:10:0 +X 3916 . C <*> 0 . DP=42;I16=16,25,0,0,1618,66342,0,0,2201,123691,0,0,825,18919,0,0;QS=3,0;MQSB=0.0757469;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,21,190:7:0 0,30,251:10:0 +X 3917 . T <*> 0 . DP=43;I16=16,25,0,0,1601,65219,0,0,2201,123691,0,0,825,18875,0,0;QS=3,0;MQSB=0.0757469;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,21,191:7:0 0,30,254:10:0 +X 3918 . T <*> 0 . DP=43;I16=16,25,0,0,1541,60711,0,0,2201,123691,0,0,801,18239,0,0;QS=3,0;MQSB=0.0757469;MQ0F=0 PL:DP:DV 0,75,255:25:0 0,18,179:6:0 0,30,254:10:0 +X 3919 . C <*> 0 . DP=42;I16=15,26,0,0,1621,66337,0,0,2232,126450,0,0,826,18786,0,0;QS=3,0;MQSB=0.110793;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,21,200:7:0 0,30,242:10:0 +X 3920 . T <*> 0 . DP=42;I16=15,26,0,0,1605,64327,0,0,2232,126450,0,0,825,18691,0,0;QS=3,0;MQSB=0.110793;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,21,207:7:0 0,30,251:10:0 +X 3921 . T <*> 0 . DP=42;I16=15,26,0,0,1519,58507,0,0,2232,126450,0,0,824,18630,0,0;QS=3,0;MQSB=0.110793;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,21,201:7:0 0,30,242:10:0 +X 3922 . A <*> 0 . DP=42;I16=14,26,0,0,1539,61289,0,0,2195,125081,0,0,819,18545,0,0;QS=3,0;MQSB=0.168991;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,18,179:6:0 0,30,244:10:0 +X 3923 . G <*> 0 . DP=41;I16=14,25,0,0,1515,60945,0,0,2135,121481,0,0,792,17834,0,0;QS=3,0;MQSB=0.182501;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,18,172:6:0 0,30,240:10:0 +X 3924 . G <*> 0 . DP=41;I16=13,26,0,0,1524,61106,0,0,2135,121481,0,0,808,18356,0,0;QS=3,0;MQSB=0.128469;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,18,158:6:0 0,30,247:10:0 +X 3925 . G <*> 0 . DP=41;I16=14,25,0,0,1425,55687,0,0,2135,121481,0,0,788,17758,0,0;QS=3,0;MQSB=0.182501;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,15,134:5:0 0,30,245:10:0 +X 3926 . C <*> 0 . DP=41;I16=14,26,0,0,1512,59674,0,0,2195,125081,0,0,811,18393,0,0;QS=3,0;MQSB=0.168991;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,18,152:6:0 0,30,237:10:0 +X 3927 . T <*> 0 . DP=41;I16=14,26,0,0,1512,59566,0,0,2195,125081,0,0,808,18384,0,0;QS=3,0;MQSB=0.168991;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,18,160:6:0 0,30,237:10:0 +X 3928 . G <*> 0 . DP=41;I16=14,25,0,0,1479,58495,0,0,2135,121481,0,0,779,17731,0,0;QS=3,0;MQSB=0.182501;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,18,149:6:0 0,27,233:9:0 +X 3929 . A <*> 0 . DP=41;I16=13,26,0,0,1452,56436,0,0,2135,121481,0,0,796,18256,0,0;QS=3,0;MQSB=0.128469;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,18,161:6:0 0,30,220:10:0 +X 3930 . T <*> 0 . DP=40;I16=13,25,0,0,1387,52929,0,0,2078,118232,0,0,767,17521,0,0;QS=3,0;MQSB=0.25797;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,15,149:5:0 0,30,224:10:0 +X 3931 . A <*> 0 . DP=40;I16=13,25,0,0,1387,52877,0,0,2078,118232,0,0,761,17439,0,0;QS=3,0;MQSB=0.25797;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,18,166:6:0 0,27,222:9:0 +X 3932 . T <*> 0 . DP=39;I16=12,26,0,0,1394,53644,0,0,2078,118232,0,0,780,17964,0,0;QS=3,0;MQSB=0.190372;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,18,161:6:0 0,30,231:10:0 +X 3933 . T <*> 0 . DP=38;I16=12,24,0,0,1389,54743,0,0,1958,111032,0,0,752,17366,0,0;QS=3,0;MQSB=0.218161;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,18,166:6:0 0,24,220:8:0 +X 3934 . C <*> 0 . DP=38;I16=12,25,0,0,1395,54915,0,0,2018,114632,0,0,768,17758,0,0;QS=3,0;MQSB=0.203497;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,18,152:6:0 0,27,209:9:0 +X 3935 . C <*> 0 . DP=38;I16=12,24,0,0,1239,44621,0,0,1958,111032,0,0,737,17075,0,0;QS=3,0;MQSB=0.218161;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,15,134:5:0 0,27,170:9:0 +X 3936 . A G,<*> 0 . DP=37;I16=5,6,6,17,424,16384,801,30271,609,34563,1314,77018,225,5325,511,11851;QS=0.87994,2.12006,0;VDB=0.0574114;SGB=-4.60123;RPB=0.741697;MQB=0.812605;MQSB=0.143788;BQB=0.883831;MQ0F=0 PL:DP:DV 233,0,206,255,239,255:20:11 77,0,58,83,70,141:6:4 196,24,0,196,24,196:8:8 +X 3937 . C <*> 0 . DP=36;I16=11,24,0,0,1155,39875,0,0,1952,112422,0,0,745,17291,0,0;QS=3,0;MQSB=0.219636;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,18,143:6:0 0,24,156:8:0 +X 3938 . G <*> 0 . DP=35;I16=11,23,0,0,1155,41761,0,0,1892,108822,0,0,737,17079,0,0;QS=3,0;MQSB=0.231054;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,15,119:5:0 0,24,176:8:0 +X 3939 . C <*> 0 . DP=35;I16=11,22,0,0,1273,50651,0,0,1832,105222,0,0,703,16221,0,0;QS=3,0;MQSB=0.243713;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,15,135:5:0 0,21,174:7:0 +X 3940 . A <*> 0 . DP=35;I16=11,22,0,0,1148,42754,0,0,1832,105222,0,0,691,15867,0,0;QS=3,0;MQSB=0.243713;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,15,117:5:0 0,21,163:7:0 +X 3941 . C <*> 0 . DP=35;I16=11,22,0,0,1216,47488,0,0,1832,105222,0,0,688,15892,0,0;QS=3,0;MQSB=0.243713;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,15,133:5:0 0,21,181:7:0 +X 3942 . C <*> 0 . DP=35;I16=11,23,0,0,1336,54166,0,0,1892,108822,0,0,690,15772,0,0;QS=3,0;MQSB=0.231054;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,15,140:5:0 0,24,195:8:0 +X 3943 . T <*> 0 . DP=35;I16=11,23,0,0,1296,51618,0,0,1892,108822,0,0,676,15406,0,0;QS=3,0;MQSB=0.231054;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,15,142:5:0 0,24,195:8:0 +X 3944 . G <*> 0 . DP=34;I16=10,22,0,0,1199,46445,0,0,1803,104381,0,0,654,14954,0,0;QS=3,0;MQSB=0.1117;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,149:5:0 0,24,195:8:0 +X 3945 . C <*> 0 . DP=33;I16=10,22,0,0,1256,51226,0,0,1772,101622,0,0,649,14657,0,0;QS=3,0;MQSB=0.187579;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,142:5:0 0,21,177:7:0 +X 3946 . T <*> 0 . DP=33;I16=10,21,0,0,1170,45884,0,0,1712,98022,0,0,609,13599,0,0;QS=3,0;MQSB=0.199344;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,144:5:0 0,18,158:6:0 +X 3947 . A <*> 0 . DP=32;I16=10,21,0,0,1094,41048,0,0,1712,98022,0,0,620,13820,0,0;QS=3,0;MQSB=0.199344;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,128:5:0 0,18,149:6:0 +X 3948 . C <*> 0 . DP=32;I16=10,20,0,0,1134,45104,0,0,1652,94422,0,0,596,13344,0,0;QS=3,0;MQSB=0.212591;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,105:4:0 0,18,155:6:0 +X 3949 . A C,<*> 0 . DP=32;I16=10,17,0,1,1027,39909,24,576,1472,83622,60,3600,541,12211,25,625;QS=2.85093,0.149068,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.244621;BQB=1;MQ0F=0 PL:DP:DV 0,60,255,60,255,255:20:0 0,9,89,9,89,89:3:0 9,0,107,21,110,124:5:1 +X 3950 . C <*> 0 . DP=33;I16=11,21,0,0,1191,46247,0,0,1772,101622,0,0,576,12680,0,0;QS=3,0;MQSB=0.257801;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,15,118:5:0 0,18,168:6:0 +X 3951 . T <*> 0 . DP=34;I16=12,19,0,0,1148,44272,0,0,1712,98022,0,0,530,11670,0,0;QS=3,0;MQSB=0.354733;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,15,146:5:0 0,15,152:5:0 +X 3952 . C <*> 0 . DP=35;I16=13,20,0,0,1176,43762,0,0,1832,105222,0,0,545,12025,0,0;QS=3,0;MQSB=0.394875;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,18,158:6:0 0,15,143:5:0 +X 3953 . C <*> 0 . DP=34;I16=13,20,0,0,1246,48436,0,0,1863,107981,0,0,538,11772,0,0;QS=3,0;MQSB=0.252983;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,18,163:6:0 0,18,168:6:0 +X 3954 . T <*> 0 . DP=33;I16=13,19,0,0,1195,45815,0,0,1803,104381,0,0,526,11438,0,0;QS=3,0;MQSB=0.264585;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,18,171:6:0 0,18,167:6:0 +X 3955 . T <*> 0 . DP=32;I16=13,18,0,0,1180,46092,0,0,1743,100781,0,0,515,11139,0,0;QS=3,0;MQSB=0.277468;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,173:6:0 0,18,174:6:0 +X 3956 . C <*> 0 . DP=32;I16=13,18,0,0,1181,47021,0,0,1743,100781,0,0,504,10874,0,0;QS=3,0;MQSB=0.277468;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,167:6:0 0,18,167:6:0 +X 3957 . T <*> 0 . DP=31;I16=13,17,0,0,1153,46051,0,0,1683,97181,0,0,494,10642,0,0;QS=3,0;MQSB=0.291833;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,161:6:0 0,15,162:5:0 +X 3958 . T <*> 0 . DP=31;I16=13,16,0,0,1070,40600,0,0,1623,93581,0,0,483,10393,0,0;QS=3,0;MQSB=0.307929;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,139:5:0 0,15,157:5:0 +X 3959 . A <*> 0 . DP=30;I16=14,15,0,0,1062,39758,0,0,1623,93581,0,0,474,10176,0,0;QS=3,0;MQSB=0.377103;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,118:4:0 0,15,154:5:0 +X 3960 . T <*> 0 . DP=30;I16=14,15,0,0,995,36027,0,0,1623,93581,0,0,464,9892,0,0;QS=3,0;MQSB=0.377103;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,105:4:0 0,15,142:5:0 +X 3961 . G <*> 0 . DP=29;I16=12,16,0,0,1067,40899,0,0,1586,92212,0,0,457,9739,0,0;QS=3,0;MQSB=0.455864;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,114:4:0 0,12,122:4:0 +X 3962 . G <*> 0 . DP=29;I16=13,16,0,0,1025,37125,0,0,1623,93581,0,0,471,10053,0,0;QS=3,0;MQSB=0.307929;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,108:4:0 0,15,144:5:0 +X 3963 . C <*> 0 . DP=28;I16=13,15,0,0,1040,39100,0,0,1563,89981,0,0,463,9871,0,0;QS=3,0;MQSB=0.326055;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,111:4:0 0,12,126:4:0 +X 3964 . T <*> 0 . DP=27;I16=12,15,0,0,1036,39928,0,0,1503,86381,0,0,456,9720,0,0;QS=3,0;MQSB=0.273507;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,9,94:3:0 0,12,133:4:0 +X 3965 . G <*> 0 . DP=26;I16=12,14,0,0,993,38165,0,0,1443,82781,0,0,450,9598,0,0;QS=3,0;MQSB=0.29215;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,9,92:3:0 0,12,134:4:0 +X 3966 . A <*> 0 . DP=26;I16=12,13,0,0,930,34834,0,0,1406,81412,0,0,432,9310,0,0;QS=3,0;MQSB=0.520812;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,90:3:0 0,12,140:4:0 +X 3967 . T <*> 0 . DP=26;I16=12,13,0,0,900,32830,0,0,1406,81412,0,0,421,9001,0,0;QS=3,0;MQSB=0.520812;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,9,90:3:0 0,9,100:3:0 +X 3968 . A <*> 0 . DP=25;I16=12,13,0,0,885,31773,0,0,1406,81412,0,0,415,8853,0,0;QS=3,0;MQSB=0.520812;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,9,90:3:0 0,9,99:3:0 +X 3969 . T <*> 0 . DP=24;I16=11,13,0,0,886,32972,0,0,1369,80043,0,0,410,8736,0,0;QS=3,0;MQSB=0.702671;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,85:3:0 0,9,108:3:0 +X 3970 . T <*> 0 . DP=24;I16=11,13,0,0,861,31313,0,0,1369,80043,0,0,405,8649,0,0;QS=3,0;MQSB=0.702671;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,83:3:0 0,9,104:3:0 +X 3971 . C <*> 0 . DP=22;I16=11,11,0,0,815,30625,0,0,1249,72843,0,0,402,8590,0,0;QS=3,0;MQSB=0.751921;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,57:2:0 0,9,103:3:0 +X 3972 . C <*> 0 . DP=22;I16=11,11,0,0,812,30486,0,0,1249,72843,0,0,399,8557,0,0;QS=3,0;MQSB=0.751921;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,55:2:0 0,9,96:3:0 +X 3973 . A <*> 0 . DP=22;I16=11,11,0,0,795,28873,0,0,1249,72843,0,0,395,8501,0,0;QS=3,0;MQSB=0.751921;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,52:2:0 0,9,97:3:0 +X 3974 . C <*> 0 . DP=22;I16=11,11,0,0,729,24447,0,0,1249,72843,0,0,392,8472,0,0;QS=3,0;MQSB=0.751921;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,55:2:0 0,9,78:3:0 +X 3975 . G <*> 0 . DP=22;I16=11,11,0,0,717,24525,0,0,1249,72843,0,0,390,8470,0,0;QS=3,0;MQSB=0.751921;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,46:2:0 0,9,96:3:0 +X 3976 . C <*> 0 . DP=22;I16=11,11,0,0,816,30652,0,0,1249,72843,0,0,387,8445,0,0;QS=3,0;MQSB=0.751921;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,55:2:0 0,9,97:3:0 +X 3977 . A <*> 0 . DP=23;I16=11,11,0,0,740,25384,0,0,1249,72843,0,0,382,8346,0,0;QS=3,0;MQSB=0.751921;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,48:2:0 0,9,90:3:0 +X 3978 . C <*> 0 . DP=23;I16=11,12,0,0,769,26631,0,0,1309,76443,0,0,377,8223,0,0;QS=3,0;MQSB=0.726094;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,47:2:0 0,9,103:3:0 +X 3979 . C <*> 0 . DP=21;I16=9,11,0,0,744,28160,0,0,1152,67874,0,0,361,7905,0,0;QS=3,0;MQSB=0.885207;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,51:2:0 0,9,104:3:0 +X 3980 . T <*> 0 . DP=21;I16=10,11,0,0,756,27872,0,0,1212,71474,0,0,367,7855,0,0;QS=3,0;MQSB=0.914611;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,51:2:0 0,9,98:3:0 +X 3981 . G <*> 0 . DP=21;I16=10,11,0,0,785,29641,0,0,1212,71474,0,0,362,7710,0,0;QS=3,0;MQSB=0.914611;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,50:2:0 0,9,93:3:0 +X 3982 . C <*> 0 . DP=21;I16=10,11,0,0,779,29495,0,0,1212,71474,0,0,357,7591,0,0;QS=3,0;MQSB=0.914611;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,55:2:0 0,9,97:3:0 +X 3983 . T <*> 0 . DP=20;I16=9,11,0,0,720,26274,0,0,1155,68225,0,0,353,7497,0,0;QS=3,0;MQSB=0.993528;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,57:2:0 0,9,93:3:0 +X 3984 . A <*> 0 . DP=21;I16=10,11,0,0,739,26279,0,0,1192,69594,0,0,348,7378,0,0;QS=3,0;MQSB=0.885602;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,53:2:0 0,9,80:3:0 +X 3985 . C <*> 0 . DP=20;I16=10,10,0,0,728,26998,0,0,1132,65994,0,0,344,7234,0,0;QS=3,0;MQSB=0.902256;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,55:2:0 0,9,91:3:0 +X 3986 . A <*> 0 . DP=20;I16=10,10,0,0,685,23815,0,0,1132,65994,0,0,340,7114,0,0;QS=3,0;MQSB=0.902256;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,56:2:0 0,9,84:3:0 +X 3987 . C <*> 0 . DP=20;I16=10,10,0,0,736,28118,0,0,1132,65994,0,0,336,7018,0,0;QS=3,0;MQSB=0.902256;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,55:2:0 0,9,94:3:0 +X 3988 . T <*> 0 . DP=21;I16=10,10,0,0,741,27797,0,0,1132,65994,0,0,332,6946,0,0;QS=3,0;MQSB=0.902256;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,58:2:0 0,9,91:3:0 +X 3989 . C <*> 0 . DP=21;I16=10,11,0,0,729,26185,0,0,1192,69594,0,0,327,6801,0,0;QS=3,0;MQSB=0.885602;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,55:2:0 0,9,88:3:0 +X 3990 . C <*> 0 . DP=21;I16=10,11,0,0,766,28674,0,0,1192,69594,0,0,322,6686,0,0;QS=3,0;MQSB=0.885602;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,55:2:0 0,9,95:3:0 +X 3991 . T <*> 0 . DP=20;I16=9,11,0,0,729,27311,0,0,1132,65994,0,0,318,6600,0,0;QS=3,0;MQSB=0.850154;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,55:2:0 0,9,89:3:0 +X 3992 . T <*> 0 . DP=19;I16=9,10,0,0,667,24173,0,0,1072,62394,0,0,313,6441,0,0;QS=3,0;MQSB=0.868634;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,56:2:0 0,6,72:2:0 +X 3993 . C <*> 0 . DP=18;I16=9,9,0,0,701,27529,0,0,1012,58794,0,0,309,6307,0,0;QS=3,0;MQSB=0.888755;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,59:2:0 0,6,70:2:0 +X 3994 . T <*> 0 . DP=19;I16=10,9,0,0,718,27520,0,0,1049,60163,0,0,305,6197,0,0;QS=3,0;MQSB=0.716531;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,58:2:0 0,6,72:2:0 +X 3995 . T <*> 0 . DP=19;I16=9,9,0,0,641,23025,0,0,989,56563,0,0,277,5487,0,0;QS=3,0;MQSB=0.650623;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,53:2:0 0,6,69:2:0 +X 3996 . A <*> 0 . DP=19;I16=9,9,0,0,665,24815,0,0,989,56563,0,0,274,5428,0,0;QS=3,0;MQSB=0.650623;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,54:2:0 0,6,73:2:0 +X 3997 . G C,<*> 0 . DP=19;I16=10,8,0,1,645,23703,21,441,989,56563,60,3600,287,5843,6,36;QS=2.96023,0.0397727,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.716531;BQB=1;MQ0F=0 PL:DP:DV 0,24,255,42,255,255:15:1 0,6,57,6,57,57:2:0 0,6,60,6,60,60:2:0 +X 3998 . G <*> 0 . DP=18;I16=9,8,0,0,626,23710,0,0,929,52963,0,0,265,5203,0,0;QS=3,0;MQSB=0.687289;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,58:2:0 0,3,36:1:0 +X 3999 . G A,<*> 0 . DP=18;I16=9,7,0,1,596,22974,37,1369,869,49363,60,3600,263,5387,4,16;QS=2.92871,0.0712909,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.687289;BQB=1;MQ0F=0 PL:DP:DV 0,5,255,39,255,255:14:1 0,6,56,6,56,56:2:0 0,3,38,3,38,38:1:0 +X 4000 . C <*> 0 . DP=18;I16=10,8,0,0,669,25389,0,0,989,56563,0,0,283,5753,0,0;QS=3,0;MQSB=0.751866;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,55:2:0 0,3,36:1:0 +X 4001 . T <*> 0 . DP=18;I16=10,8,0,0,680,26006,0,0,989,56563,0,0,279,5727,0,0;QS=3,0;MQSB=0.751866;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,56:2:0 0,3,33:1:0 +X 4002 . G <*> 0 . DP=17;I16=10,7,0,0,621,23281,0,0,929,52963,0,0,276,5724,0,0;QS=2,0;MQSB=0.79189;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,44:2:0 0,0,0:0:0 +X 4003 . A <*> 0 . DP=17;I16=10,7,0,0,597,21507,0,0,929,52963,0,0,272,5692,0,0;QS=2,0;MQSB=0.79189;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,55:2:0 0,0,0:0:0 +X 4004 . T <*> 0 . DP=15;I16=9,6,0,0,527,19031,0,0,849,48963,0,0,270,5678,0,0;QS=2,0;MQSB=0.957526;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,40:1:0 0,0,0:0:0 +X 4005 . A <*> 0 . DP=15;I16=8,5,0,0,479,17731,0,0,729,41763,0,0,237,5195,0,0;QS=2,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,35:1:0 0,0,0:0:0 +X 4006 . T <*> 0 . DP=15;I16=9,6,0,0,554,20776,0,0,849,48963,0,0,266,5698,0,0;QS=2,0;MQSB=0.957526;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,40:1:0 0,0,0:0:0 +X 4007 . T G,<*> 0 . DP=15;I16=9,5,0,1,490,17810,15,225,789,45363,60,3600,245,5371,19,361;QS=1.96746,0.032538,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.957526;BQB=1;MQ0F=0 PL:DP:DV 0,26,255,39,255,255:14:1 0,3,41,3,41,41:1:0 0,0,0,0,0,0:0:0 +X 4008 . C <*> 0 . DP=15;I16=9,6,0,0,488,16890,0,0,849,48963,0,0,262,5782,0,0;QS=2,0;MQSB=0.957526;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,30:1:0 0,0,0:0:0 +X 4009 . C <*> 0 . DP=14;I16=9,5,0,0,524,20150,0,0,794,45938,0,0,261,5847,0,0;QS=2,0;MQSB=0.800737;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,40:1:0 0,0,0:0:0 +X 4010 . A <*> 0 . DP=14;I16=9,5,0,0,523,19731,0,0,794,45938,0,0,259,5875,0,0;QS=2,0;MQSB=0.800737;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,41:1:0 0,0,0:0:0 +X 4011 . C <*> 0 . DP=14;I16=9,5,0,0,489,17613,0,0,794,45938,0,0,257,5915,0,0;QS=2,0;MQSB=0.800737;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,41:1:0 0,0,0:0:0 +X 4012 . A <*> 0 . DP=14;I16=7,5,0,0,365,11867,0,0,674,38738,0,0,223,5293,0,0;QS=2,0;MQSB=0.6821;MQ0F=0 PL:DP:DV 0,33,231:11:0 0,3,30:1:0 0,0,0:0:0 +X 4013 . C <*> 0 . DP=14;I16=8,5,0,0,451,15885,0,0,734,42338,0,0,247,5995,0,0;QS=2,0;MQSB=0.765017;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,37:1:0 0,0,0:0:0 +X 4014 . A <*> 0 . DP=12;I16=8,2,0,0,358,13372,0,0,554,31538,0,0,222,5404,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,213:9:0 0,3,34:1:0 0,0,0:0:0 +X 4015 . C <*> 0 . DP=12;I16=8,2,0,0,350,12812,0,0,554,31538,0,0,222,5442,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,222:9:0 0,3,21:1:0 0,0,0:0:0 +X 4016 . C <*> 0 . DP=12;I16=8,3,0,0,350,11956,0,0,614,35138,0,0,247,6109,0,0;QS=2,0;MQSB=0.829029;MQ0F=0 PL:DP:DV 0,30,215:10:0 0,3,32:1:0 0,0,0:0:0 +X 4017 . C <*> 0 . DP=11;I16=5,2,0,0,227,7765,0,0,374,20738,0,0,173,4279,0,0;QS=2,0;MQSB=0.6;MQ0F=0 PL:DP:DV 0,18,161:6:0 0,3,20:1:0 0,0,0:0:0 +X 4018 . G <*> 0 . DP=11;I16=8,2,0,0,284,8442,0,0,554,31538,0,0,249,6201,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,183:9:0 0,3,17:1:0 0,0,0:0:0 +X 4019 . C <*> 0 . DP=11;I16=9,2,0,0,383,14427,0,0,614,35138,0,0,250,6250,0,0;QS=2,0;MQSB=0.777778;MQ0F=0 PL:DP:DV 0,30,228:10:0 0,3,33:1:0 0,0,0:0:0 +X 4020 . T <*> 0 . DP=10;I16=8,2,0,0,362,13668,0,0,554,31538,0,0,250,6250,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,213:9:0 0,3,38:1:0 0,0,0:0:0 +X 4021 . A <*> 0 . DP=10;I16=8,1,0,0,304,10512,0,0,494,27938,0,0,225,5625,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,177:8:0 0,3,33:1:0 0,0,0:0:0 +X 4022 . C <*> 0 . DP=10;I16=7,2,0,0,310,11582,0,0,494,27938,0,0,225,5625,0,0;QS=2,0;MQSB=0.714286;MQ0F=0 PL:DP:DV 0,24,202:8:0 0,3,36:1:0 0,0,0:0:0 +X 4023 . A <*> 0 . DP=10;I16=8,2,0,0,354,13116,0,0,554,31538,0,0,250,6250,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,209:9:0 0,3,40:1:0 0,0,0:0:0 +X 4024 . C <*> 0 . DP=10;I16=8,2,0,0,361,13669,0,0,554,31538,0,0,250,6250,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,214:9:0 0,3,39:1:0 0,0,0:0:0 +X 4025 . T <*> 0 . DP=10;I16=8,1,0,0,360,14488,0,0,494,27938,0,0,224,5576,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,199:8:0 0,3,42:1:0 0,0,0:0:0 +X 4026 . C <*> 0 . DP=10;I16=8,2,0,0,329,11655,0,0,554,31538,0,0,248,6154,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,192:9:0 0,3,39:1:0 0,0,0:0:0 +X 4027 . C <*> 0 . DP=10;I16=8,2,0,0,380,14888,0,0,554,31538,0,0,246,6060,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,231:9:0 0,3,38:1:0 0,0,0:0:0 +X 4028 . T <*> 0 . DP=10;I16=8,2,0,0,333,12157,0,0,554,31538,0,0,244,5970,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,202:9:0 0,3,41:1:0 0,0,0:0:0 +X 4029 . T <*> 0 . DP=10;I16=8,2,0,0,377,14333,0,0,554,31538,0,0,242,5884,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,225:9:0 0,3,38:1:0 0,0,0:0:0 +X 4030 . C <*> 0 . DP=10;I16=8,2,0,0,348,12558,0,0,554,31538,0,0,240,5802,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,211:9:0 0,3,30:1:0 0,0,0:0:0 +X 4031 . T <*> 0 . DP=10;I16=8,2,0,0,388,15302,0,0,554,31538,0,0,238,5724,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,229:9:0 0,3,39:1:0 0,0,0:0:0 +X 4032 . T <*> 0 . DP=10;I16=8,2,0,0,341,11901,0,0,554,31538,0,0,236,5650,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,204:9:0 0,3,39:1:0 0,0,0:0:0 +X 4033 . A <*> 0 . DP=10;I16=7,2,0,0,299,10717,0,0,494,27938,0,0,218,5324,0,0;QS=2,0;MQSB=0.714286;MQ0F=0 PL:DP:DV 0,24,193:8:0 0,3,38:1:0 0,0,0:0:0 +X 4034 . G <*> 0 . DP=10;I16=8,2,0,0,347,12527,0,0,554,31538,0,0,231,5465,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,211:9:0 0,3,39:1:0 0,0,0:0:0 +X 4035 . G T,<*> 0 . DP=10;I16=7,2,1,0,316,11900,13,169,494,27938,60,3600,202,4682,25,625;QS=1.9547,0.0452962,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.75;BQB=1;MQ0F=0 PL:DP:DV 0,13,195,24,198,200:9:1 0,3,31,3,31,31:1:0 0,0,0,0,0,0:0:0 +X 4036 . G <*> 0 . DP=10;I16=8,1,0,0,269,8839,0,0,494,27938,0,0,198,4532,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,156:8:0 0,3,34:1:0 0,0,0:0:0 +X 4037 . C <*> 0 . DP=10;I16=8,2,0,0,342,12466,0,0,554,31538,0,0,219,5015,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,210:9:0 0,3,30:1:0 0,0,0:0:0 +X 4038 . T <*> 0 . DP=10;I16=8,2,0,0,335,12149,0,0,554,31538,0,0,215,4881,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,203:9:0 0,3,29:1:0 0,0,0:0:0 +X 4039 . G <*> 0 . DP=10;I16=8,1,0,0,302,10798,0,0,494,27938,0,0,186,4130,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,180:8:0 0,3,31:1:0 0,0,0:0:0 +X 4040 . A <*> 0 . DP=10;I16=8,2,0,0,380,14602,0,0,554,31538,0,0,207,4637,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,223:9:0 0,3,41:1:0 0,0,0:0:0 +X 4041 . T <*> 0 . DP=10;I16=8,2,0,0,367,13633,0,0,554,31538,0,0,202,4478,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,216:9:0 0,3,40:1:0 0,0,0:0:0 +X 4042 . A <*> 0 . DP=10;I16=8,2,0,0,337,11657,0,0,554,31538,0,0,197,4329,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,205:9:0 0,3,34:1:0 0,0,0:0:0 +X 4043 . T <*> 0 . DP=10;I16=8,2,0,0,314,10428,0,0,554,31538,0,0,192,4190,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,190:9:0 0,3,35:1:0 0,0,0:0:0 +X 4044 . T <*> 0 . DP=10;I16=8,2,0,0,333,11579,0,0,554,31538,0,0,187,4061,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,199:9:0 0,3,37:1:0 0,0,0:0:0 +X 4045 . C <*> 0 . DP=10;I16=7,2,0,0,291,10099,0,0,494,27938,0,0,176,3906,0,0;QS=1,0;MQSB=0.714286;MQ0F=0 PL:DP:DV 0,27,204:9:0 0,0,0:0:0 0,0,0:0:0 +X 4046 . C <*> 0 . DP=10;I16=8,2,0,0,356,13032,0,0,554,31538,0,0,177,3833,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,212:9:0 0,3,35:1:0 0,0,0:0:0 +X 4047 . A <*> 0 . DP=10;I16=8,2,0,0,347,12557,0,0,554,31538,0,0,172,3734,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,204:9:0 0,3,40:1:0 0,0,0:0:0 +X 4048 . C <*> 0 . DP=10;I16=8,2,0,0,342,12124,0,0,554,31538,0,0,167,3645,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,202:9:0 0,3,37:1:0 0,0,0:0:0 +X 4049 . G <*> 0 . DP=10;I16=7,2,0,0,260,7786,0,0,494,27938,0,0,146,3310,0,0;QS=2,0;MQSB=0.714286;MQ0F=0 PL:DP:DV 0,24,173:8:0 0,3,24:1:0 0,0,0:0:0 +X 4050 . C <*> 0 . DP=9;I16=6,2,0,0,291,10813,0,0,434,24338,0,0,157,3495,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL:DP:DV 0,24,204:8:0 0,0,0:0:0 0,0,0:0:0 +X 4051 . A <*> 0 . DP=8;I16=5,2,0,0,259,9679,0,0,374,20738,0,0,146,3370,0,0;QS=1,0;MQSB=0.6;MQ0F=0 PL:DP:DV 0,21,192:7:0 0,0,0:0:0 0,0,0:0:0 +X 4052 . C <*> 0 . DP=8;I16=5,2,0,0,247,9025,0,0,374,20738,0,0,143,3281,0,0;QS=1,0;MQSB=0.6;MQ0F=0 PL:DP:DV 0,21,190:7:0 0,0,0:0:0 0,0,0:0:0 +X 4053 . C <*> 0 . DP=8;I16=6,2,0,0,254,9000,0,0,434,24338,0,0,146,3234,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL:DP:DV 0,24,184:8:0 0,0,0:0:0 0,0,0:0:0 +X 4054 . C <*> 0 . DP=8;I16=3,2,0,0,160,5344,0,0,254,13538,0,0,122,2984,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,134:5:0 0,0,0:0:0 0,0,0:0:0 +X 4055 . G <*> 0 . DP=8;I16=6,2,0,0,230,6982,0,0,434,24338,0,0,138,3066,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL:DP:DV 0,24,169:8:0 0,0,0:0:0 0,0,0:0:0 +X 4056 . C <*> 0 . DP=8;I16=6,2,0,0,275,10153,0,0,434,24338,0,0,134,2994,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL:DP:DV 0,24,197:8:0 0,0,0:0:0 0,0,0:0:0 +X 4057 . T <*> 0 . DP=8;I16=5,2,0,0,243,8603,0,0,374,20738,0,0,127,2877,0,0;QS=1,0;MQSB=0.6;MQ0F=0 PL:DP:DV 0,21,182:7:0 0,0,0:0:0 0,0,0:0:0 +X 4058 . A <*> 0 . DP=7;I16=4,2,0,0,214,7742,0,0,314,17138,0,0,116,2728,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,171:6:0 0,0,0:0:0 0,0,0:0:0 +X 4059 . C <*> 0 . DP=6;I16=4,2,0,0,204,7164,0,0,314,17138,0,0,119,2635,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,168:6:0 0,0,0:0:0 0,0,0:0:0 +X 4060 . A <*> 0 . DP=6;I16=4,2,0,0,227,8683,0,0,314,17138,0,0,115,2501,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,177:6:0 0,0,0:0:0 0,0,0:0:0 +X 4061 . C <*> 0 . DP=6;I16=4,2,0,0,193,6681,0,0,314,17138,0,0,111,2375,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,157:6:0 0,0,0:0:0 0,0,0:0:0 +X 4062 . T <*> 0 . DP=6;I16=4,1,0,0,195,7621,0,0,254,13538,0,0,82,1632,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,151:5:0 0,0,0:0:0 0,0,0:0:0 +X 4063 . C <*> 0 . DP=6;I16=4,2,0,0,216,7984,0,0,314,17138,0,0,102,2098,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,170:6:0 0,0,0:0:0 0,0,0:0:0 +X 4064 . C <*> 0 . DP=6;I16=4,2,0,0,227,8747,0,0,314,17138,0,0,97,1949,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,177:6:0 0,0,0:0:0 0,0,0:0:0 +X 4065 . T <*> 0 . DP=6;I16=4,2,0,0,202,6880,0,0,314,17138,0,0,92,1810,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,161:6:0 0,0,0:0:0 0,0,0:0:0 +X 4066 . T <*> 0 . DP=5;I16=3,2,0,0,180,6554,0,0,254,13538,0,0,88,1680,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,153:5:0 0,0,0:0:0 0,0,0:0:0 +X 4067 . C <*> 0 . DP=5;I16=3,2,0,0,181,6637,0,0,254,13538,0,0,84,1558,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,153:5:0 0,0,0:0:0 0,0,0:0:0 +X 4068 . T <*> 0 . DP=5;I16=3,2,0,0,198,7868,0,0,254,13538,0,0,80,1444,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,164:5:0 0,0,0:0:0 0,0,0:0:0 +X 4069 . T <*> 0 . DP=5;I16=3,2,0,0,177,6325,0,0,254,13538,0,0,76,1338,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,154:5:0 0,0,0:0:0 0,0,0:0:0 +X 4070 . A <*> 0 . DP=5;I16=3,2,0,0,161,5263,0,0,254,13538,0,0,72,1240,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,140:5:0 0,0,0:0:0 0,0,0:0:0 +X 4071 . G <*> 0 . DP=5;I16=3,2,0,0,166,5658,0,0,254,13538,0,0,68,1150,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,142:5:0 0,0,0:0:0 0,0,0:0:0 +X 4072 . G <*> 0 . DP=5;I16=2,2,0,0,138,4974,0,0,194,9938,0,0,55,987,0,0;QS=1,0;MQSB=0;MQ0F=0 PL:DP:DV 0,12,122:4:0 0,0,0:0:0 0,0,0:0:0 +X 4073 . G <*> 0 . DP=5;I16=3,2,0,0,156,5082,0,0,254,13538,0,0,60,994,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,136:5:0 0,0,0:0:0 0,0,0:0:0 +X 4074 . C <*> 0 . DP=5;I16=3,2,0,0,160,5602,0,0,254,13538,0,0,56,928,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,142:5:0 0,0,0:0:0 0,0,0:0:0 +X 4075 . T <*> 0 . DP=5;I16=3,2,0,0,187,7069,0,0,254,13538,0,0,52,870,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,155:5:0 0,0,0:0:0 0,0,0:0:0 +X 4076 . G <*> 0 . DP=5;I16=3,2,0,0,174,6298,0,0,254,13538,0,0,48,820,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,149:5:0 0,0,0:0:0 0,0,0:0:0 +X 4077 . A <*> 0 . DP=4;I16=3,1,0,0,138,4810,0,0,194,9938,0,0,44,728,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,12,121:4:0 0,0,0:0:0 0,0,0:0:0 +X 4078 . T <*> 0 . DP=4;I16=3,1,0,0,143,5173,0,0,194,9938,0,0,40,644,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,12,124:4:0 0,0,0:0:0 0,0,0:0:0 +X 4079 . A <*> 0 . DP=4;I16=3,1,0,0,121,3847,0,0,194,9938,0,0,36,568,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,12,107:4:0 0,0,0:0:0 0,0,0:0:0 +X 4080 . T <*> 0 . DP=4;I16=3,0,0,0,106,3778,0,0,134,6338,0,0,25,451,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,9,87:3:0 0,0,0:0:0 0,0,0:0:0 +X 4081 . T <*> 0 . DP=4;I16=3,1,0,0,106,2934,0,0,194,9938,0,0,28,440,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,12,94:4:0 0,0,0:0:0 0,0,0:0:0 +X 4082 . C <*> 0 . DP=3;I16=2,1,0,0,110,4042,0,0,134,6338,0,0,25,387,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,9,103:3:0 0,0,0:0:0 0,0,0:0:0 +X 4083 . C <*> 0 . DP=3;I16=2,1,0,0,104,3648,0,0,134,6338,0,0,22,340,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,9,98:3:0 0,0,0:0:0 0,0,0:0:0 +X 4084 . A <*> 0 . DP=2;I16=1,1,0,0,78,3050,0,0,97,4969,0,0,20,298,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,6,74:2:0 0,0,0:0:0 0,0,0:0:0 +X 4085 . C <*> 0 . DP=2;I16=1,1,0,0,62,1940,0,0,97,4969,0,0,18,260,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,6,62:2:0 0,0,0:0:0 0,0,0:0:0 +X 4086 . G <*> 0 . DP=2;I16=1,1,0,0,56,1640,0,0,97,4969,0,0,16,226,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,6,56:2:0 0,0,0:0:0 0,0,0:0:0 +X 4087 . C <*> 0 . DP=2;I16=1,1,0,0,69,2405,0,0,97,4969,0,0,14,196,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,6,68:2:0 0,0,0:0:0 0,0,0:0:0 +X 4088 . A <*> 0 . DP=1;I16=1,0,0,0,39,1521,0,0,37,1369,0,0,13,169,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,37:1:0 0,0,0:0:0 0,0,0:0:0 +X 4089 . C <*> 0 . DP=1;I16=1,0,0,0,36,1296,0,0,37,1369,0,0,12,144,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,36:1:0 0,0,0:0:0 0,0,0:0:0 +X 4090 . C <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,37,1369,0,0,11,121,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,33:1:0 0,0,0:0:0 0,0,0:0:0 +X 4091 . T <*> 0 . DP=1;I16=1,0,0,0,36,1296,0,0,37,1369,0,0,10,100,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,36:1:0 0,0,0:0:0 0,0,0:0:0 +X 4092 . G <*> 0 . DP=1;I16=1,0,0,0,37,1369,0,0,37,1369,0,0,9,81,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,37:1:0 0,0,0:0:0 0,0,0:0:0 +X 4093 . C <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,37,1369,0,0,8,64,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,35:1:0 0,0,0:0:0 0,0,0:0:0 +X 4094 . T <*> 0 . DP=1;I16=1,0,0,0,40,1600,0,0,37,1369,0,0,7,49,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,37:1:0 0,0,0:0:0 0,0,0:0:0 +X 4095 . A <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,37,1369,0,0,6,36,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,35:1:0 0,0,0:0:0 0,0,0:0:0 +X 4096 . C <*> 0 . DP=1;I16=1,0,0,0,32,1024,0,0,37,1369,0,0,5,25,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,32:1:0 0,0,0:0:0 0,0,0:0:0 +X 4097 . A <*> 0 . DP=1;I16=1,0,0,0,35,1225,0,0,37,1369,0,0,4,16,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,35:1:0 0,0,0:0:0 0,0,0:0:0 +X 4098 . C <*> 0 . DP=1;I16=1,0,0,0,31,961,0,0,37,1369,0,0,3,9,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,31:1:0 0,0,0:0:0 0,0,0:0:0 +X 4099 . T <*> 0 . DP=1;I16=1,0,0,0,32,1024,0,0,37,1369,0,0,2,4,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,32:1:0 0,0,0:0:0 0,0,0:0:0 +X 4100 . C <*> 0 . DP=1;I16=1,0,0,0,27,729,0,0,37,1369,0,0,1,1,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,27:1:0 0,0,0:0:0 0,0,0:0:0 +X 4101 . C <*> 0 . DP=1;I16=1,0,0,0,26,676,0,0,37,1369,0,0,0,0,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,26:1:0 0,0,0:0:0 0,0,0:0:0 diff --git a/test/mpileup.c.vcf b/test/mpileup.c.vcf new file mode 100644 index 0000000..13c0132 --- /dev/null +++ b/test/mpileup.c.vcf @@ -0,0 +1,4127 @@ +##fileformat=VCFv4.2 +##FILTER= +##samtoolsVersion=1.1-19-g6b249e2+htslib-1.1-74-g845c515 +##samtoolsCommand=samtools mpileup -uvDV -b xxx//mpileup.bam.list -f xxx//mpileup.ref.fa.gz +##reference=file://xxx//mpileup.ref.fa.gz +##contig= +##ALT= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT HG00100 HG00101 HG00102 +17 1 . A 0 . DP=11;I16=11,0,0,0,452,18594,0,0,319,9251,0,0,223,4959,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 +17 2 . A 0 . DP=11;I16=11,0,0,0,439,17587,0,0,319,9251,0,0,226,5030,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 +17 3 . G 0 . DP=11;I16=11,0,0,0,431,16971,0,0,319,9251,0,0,229,5111,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 +17 4 . C 0 . DP=11;I16=11,0,0,0,423,16417,0,0,319,9251,0,0,232,5202,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,71:3:0 +17 5 . T 0 . DP=11;I16=11,0,0,0,450,18520,0,0,319,9251,0,0,234,5252,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 +17 6 . T 0 . DP=11;I16=11,0,0,0,403,14847,0,0,319,9251,0,0,236,5310,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 +17 7 . C 0 . DP=11;I16=11,0,0,0,446,18114,0,0,319,9251,0,0,237,5327,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 +17 8 . T 0 . DP=11;I16=11,0,0,0,465,19677,0,0,319,9251,0,0,238,5354,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 +17 9 . C 0 . DP=11;I16=11,0,0,0,447,18205,0,0,319,9251,0,0,239,5391,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 +17 10 . A 0 . DP=11;I16=11,0,0,0,426,16756,0,0,319,9251,0,0,240,5438,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,69:3:0 +17 11 . C 0 . DP=11;I16=11,0,0,0,413,15603,0,0,319,9251,0,0,241,5495,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 +17 12 . C 0 . DP=11;I16=11,0,0,0,438,17506,0,0,319,9251,0,0,242,5562,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 +17 13 . C 0 . DP=11;I16=11,0,0,0,437,17463,0,0,319,9251,0,0,243,5639,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 +17 14 . T 0 . DP=11;I16=11,0,0,0,453,18715,0,0,319,9251,0,0,242,5628,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 +17 15 . G 0 . DP=11;I16=11,0,0,0,439,17599,0,0,319,9251,0,0,240,5580,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 +17 16 . T 0 . DP=11;I16=11,0,0,0,426,16546,0,0,319,9251,0,0,238,5544,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 +17 17 . T 0 . DP=11;I16=11,0,0,0,407,15195,0,0,319,9251,0,0,235,5469,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 +17 18 . C 0 . DP=12;I16=12,0,0,0,450,17136,0,0,379,12851,0,0,231,5353,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,113:6:0 0,9,72:3:0 0,9,72:3:0 +17 19 . C 0 . DP=13;I16=13,0,0,0,502,19652,0,0,439,16451,0,0,228,5246,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,112:6:0 0,12,89:4:0 0,9,72:3:0 +17 20 . T 0 . DP=13;I16=13,0,0,0,532,21878,0,0,439,16451,0,0,226,5150,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,116:6:0 0,12,98:4:0 0,9,72:3:0 +17 21 . G 0 . DP=13;I16=13,0,0,0,498,19254,0,0,439,16451,0,0,224,5066,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,117:6:0 0,12,94:4:0 0,9,72:3:0 +17 22 . C 0 . DP=13;I16=13,0,0,0,511,20289,0,0,470,19210,0,0,223,4993,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,115:6:0 0,12,91:4:0 0,9,76:3:0 +17 23 . A 0 . DP=14;I16=14,0,0,0,513,19399,0,0,530,22810,0,0,223,4931,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,133:7:0 0,12,82:4:0 0,9,82:3:0 +17 24 . T 0 . DP=14;I16=14,0,0,0,534,20540,0,0,530,22810,0,0,224,4882,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,131:7:0 0,12,96:4:0 0,9,80:3:0 +17 25 . A 0 . DP=15;I16=15,0,0,0,561,21133,0,0,590,26410,0,0,225,4847,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,140:8:0 0,12,96:4:0 0,9,81:3:0 +17 26 . G 0 . DP=15;I16=15,0,0,0,591,23429,0,0,590,26410,0,0,227,4827,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,151:8:0 0,12,96:4:0 0,9,81:3:0 +17 27 . A 0 . DP=15;I16=15,0,0,0,588,23120,0,0,590,26410,0,0,229,4823,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,146:8:0 0,12,98:4:0 0,9,83:3:0 +17 28 . T 0 . DP=16;I16=16,0,0,0,605,23001,0,0,650,30010,0,0,231,4835,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,147:8:0 0,12,97:4:0 0,12,101:4:0 +17 29 . A 0 . DP=17;I16=17,0,0,0,615,22533,0,0,710,33610,0,0,234,4864,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,146:8:0 0,15,102:5:0 0,12,104:4:0 +17 30 . A 0 . DP=17;I16=17,0,0,0,660,25914,0,0,710,33610,0,0,238,4912,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,149:8:0 0,15,115:5:0 0,12,108:4:0 +17 31 . T 0 . DP=17;I16=17,0,0,0,656,25392,0,0,710,33610,0,0,242,4980,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,150:8:0 0,15,113:5:0 0,12,105:4:0 +17 32 . T 0 . DP=17;I16=17,0,0,0,605,21789,0,0,741,36369,0,0,247,5067,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,143:8:0 0,15,104:5:0 0,12,104:4:0 +17 33 . G 0 . DP=17;I16=17,0,0,0,659,25757,0,0,741,36369,0,0,252,5124,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,158:8:0 0,15,118:5:0 0,12,105:4:0 +17 34 . C 0 . DP=17;I16=17,0,0,0,658,25704,0,0,741,36369,0,0,257,5203,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,151:8:0 0,15,121:5:0 0,12,106:4:0 +17 35 . A 0 . DP=18;I16=18,0,0,0,677,25881,0,0,801,39969,0,0,262,5304,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,152:8:0 0,15,109:5:0 0,15,121:5:0 +17 36 . T 0 . DP=18;I16=18,0,0,0,678,25796,0,0,801,39969,0,0,268,5428,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,151:8:0 0,15,114:5:0 0,15,125:5:0 +17 37 . G 0 . DP=18;I16=18,0,0,0,685,26291,0,0,801,39969,0,0,274,5576,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,157:8:0 0,15,116:5:0 0,15,126:5:0 +17 38 . A 0 . DP=18;I16=18,0,0,0,697,27245,0,0,801,39969,0,0,280,5748,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,152:8:0 0,15,116:5:0 0,15,129:5:0 +17 39 . C 0 . DP=16;I16=16,0,0,0,591,22311,0,0,743,38287,0,0,288,5942,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,148:7:0 0,12,94:4:0 0,15,123:5:0 +17 40 . A 0 . DP=16;I16=16,0,0,0,630,24896,0,0,743,38287,0,0,295,6107,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,146:7:0 0,12,104:4:0 0,15,127:5:0 +17 41 . A 0 . DP=17;I16=17,0,0,0,645,24685,0,0,803,41887,0,0,302,6294,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,151:8:0 0,12,104:4:0 0,15,131:5:0 +17 42 . T 0 . DP=17;I16=17,0,0,0,618,23118,0,0,803,41887,0,0,310,6504,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,155:8:0 0,12,82:4:0 0,15,127:5:0 +17 43 . T 0 . DP=17;I16=17,0,0,0,631,23689,0,0,803,41887,0,0,318,6738,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,151:8:0 0,12,101:4:0 0,15,129:5:0 +17 44 . G 0 . DP=17;I16=17,0,0,0,664,26162,0,0,803,41887,0,0,324,6896,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,164:8:0 0,12,100:4:0 0,15,129:5:0 +17 45 . C 0 . DP=17;I16=17,0,0,0,657,25525,0,0,803,41887,0,0,329,7027,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,163:8:0 0,12,108:4:0 0,15,125:5:0 +17 46 . C 0 . DP=17;I16=17,0,0,0,646,25244,0,0,803,41887,0,0,334,7180,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,161:8:0 0,12,98:4:0 0,15,131:5:0 +17 47 . T 0 . DP=17;I16=17,0,0,0,700,28998,0,0,803,41887,0,0,339,7355,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,165:8:0 0,12,110:4:0 0,15,136:5:0 +17 48 . T 0 . DP=17;I16=17,0,0,0,648,25020,0,0,803,41887,0,0,343,7501,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,155:8:0 0,12,105:4:0 0,15,131:5:0 +17 49 . G 0 . DP=18;I16=18,0,0,0,686,26674,0,0,832,42728,0,0,346,7616,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,158:8:0 0,15,119:5:0 0,15,128:5:0 +17 50 . T 0 . DP=18;I16=17,0,0,0,650,24972,0,0,772,39128,0,0,332,7426,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,155:8:0 0,12,101:4:0 0,15,128:5:0 +17 51 . C 0 . DP=18;I16=18,0,0,0,681,26529,0,0,832,42728,0,0,353,7853,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,167:8:0 0,15,99:5:0 0,15,127:5:0 +17 52 . C 0 . DP=18;I16=17,0,0,0,645,24983,0,0,803,41887,0,0,353,7965,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,164:8:0 0,12,99:4:0 0,15,128:5:0 +17 53 . C 0 . DP=18;I16=18,0,0,0,687,26735,0,0,832,42728,0,0,359,8113,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,164:8:0 0,15,113:5:0 0,15,132:5:0 +17 54 . T 0 . DP=18;I16=18,0,0,0,736,30194,0,0,832,42728,0,0,361,8219,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,163:8:0 0,15,128:5:0 0,15,136:5:0 +17 55 . G 0 . DP=18;I16=18,0,0,0,674,26082,0,0,832,42728,0,0,362,8290,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,168:8:0 0,15,112:5:0 0,15,122:5:0 +17 56 . C 0 . DP=18;I16=18,0,0,0,701,27645,0,0,832,42728,0,0,363,8375,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,162:8:0 0,15,121:5:0 0,15,131:5:0 +17 57 . T 0 . DP=18;I16=17,0,0,0,694,29118,0,0,803,41887,0,0,356,8410,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,163:8:0 0,12,117:4:0 0,15,138:5:0 +17 58 . G 0 . DP=17;I16=16,0,0,0,616,24356,0,0,774,41046,0,0,356,8454,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,159:7:0 0,12,95:4:0 0,15,131:5:0 +17 59 . A 0 . DP=17;I16=17,0,0,0,656,26038,0,0,803,41887,0,0,366,8606,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,155:7:0 0,15,116:5:0 0,15,134:5:0 +17 60 . A 0 . DP=17;I16=17,0,0,0,663,26463,0,0,803,41887,0,0,367,8687,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,151:7:0 0,15,127:5:0 0,15,138:5:0 +17 61 . T 0 . DP=17;I16=16,0,0,0,605,23215,0,0,774,41046,0,0,355,8583,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,152:7:0 0,12,101:4:0 0,15,131:5:0 +17 62 . G 0 . DP=18;I16=17,0,0,0,646,24868,0,0,834,44646,0,0,353,8557,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,158:7:0 0,12,103:4:0 0,18,141:6:0 +17 63 . T 0 . DP=18;I16=17,0,0,0,590,21682,0,0,803,41887,0,0,341,8111,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,148:7:0 0,12,80:4:0 0,18,144:6:0 +17 64 . G 0 . DP=19;I16=19,0,0,0,696,26416,0,0,923,49087,0,0,366,8758,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,169:8:0 0,15,103:5:0 0,18,142:6:0 +17 65 . C 0 . DP=18;I16=18,0,0,0,686,26512,0,0,894,48246,0,0,367,8743,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,163:7:0 0,15,116:5:0 0,18,147:6:0 +17 66 . T 0 . DP=18;I16=17,0,0,0,691,28315,0,0,834,44646,0,0,342,8068,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,164:7:0 0,12,110:4:0 0,18,153:6:0 +17 67 . C 0 . DP=17;I16=17,0,0,0,645,25313,0,0,834,44646,0,0,341,7983,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,163:7:0 0,12,94:4:0 0,18,147:6:0 +17 68 . T 0 . DP=17;I16=17,0,0,0,691,28307,0,0,834,44646,0,0,339,7863,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,165:7:0 0,12,108:4:0 0,18,151:6:0 +17 69 . G 0 . DP=17;I16=17,0,0,0,657,25721,0,0,865,47405,0,0,338,7758,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,172:8:0 0,9,93:3:0 0,18,142:6:0 +17 70 . G 0 . DP=17;I16=16,0,0,0,575,21391,0,0,836,46564,0,0,317,7227,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,162:8:0 0,6,64:2:0 0,18,141:6:0 +17 71 . G 0 . DP=17;I16=15,0,0,0,571,21975,0,0,776,42964,0,0,307,7029,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,170:8:0 0,6,72:2:0 0,15,130:5:0 +17 72 . G 0 . DP=17;I16=15,0,0,0,572,22002,0,0,776,42964,0,0,305,6907,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,171:8:0 0,6,65:2:0 0,15,131:5:0 +17 73 . T 0 . DP=18;I16=16,0,0,0,623,25301,0,0,836,46564,0,0,314,6918,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,158:8:0 0,6,94:2:0 0,18,143:6:0 +17 74 . C 0 . DP=18;I16=17,0,0,0,674,28110,0,0,865,47405,0,0,338,7468,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,176:8:0 0,9,106:3:0 0,18,141:6:0 +17 75 . T 0 . DP=18;I16=16,0,0,0,685,30675,0,0,836,46564,0,0,312,6782,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,175:8:0 0,6,90:2:0 0,18,150:6:0 +17 76 . C 0 . DP=18;I16=17,0,0,0,683,29481,0,0,865,47405,0,0,336,7360,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,174:8:0 0,9,98:3:0 0,18,148:6:0 +17 77 . T 0 . DP=18;I16=16,0,0,0,710,33072,0,0,836,46564,0,0,310,6702,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,179:8:0 0,6,92:2:0 0,18,154:6:0 +17 78 . G 0 . DP=18;I16=16,0,0,0,692,31158,0,0,836,46564,0,0,309,6683,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,180:8:0 0,6,94:2:0 0,18,149:6:0 +17 79 . G 0 . DP=18;I16=15,0,0,0,605,26629,0,0,776,42964,0,0,283,6053,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,168:8:0 0,3,60:1:0 0,18,149:6:0 +17 80 . G 0 . DP=18;I16=17,0,0,0,688,30128,0,0,865,47405,0,0,332,7312,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,173:8:0 0,9,106:3:0 0,18,151:6:0 +17 81 . G 0 . DP=18;I16=16,0,0,0,631,27429,0,0,836,46564,0,0,326,7310,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,165:7:0 0,9,97:3:0 0,18,145:6:0 +17 82 . T 0 . DP=18;I16=15,0,0,0,559,22735,0,0,776,42964,0,0,280,6122,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,154:8:0 0,3,60:1:0 0,18,131:6:0 +17 83 . C 0 . DP=18;I16=16,0,0,0,622,27146,0,0,836,46564,0,0,304,6798,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,170:8:0 0,6,75:2:0 0,18,145:6:0 +17 84 . T 0 . DP=18;I16=17,0,0,0,705,32445,0,0,865,47405,0,0,328,7488,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,181:8:0 0,9,85:3:0 0,18,154:6:0 +17 85 . C 0 . DP=18;I16=17,0,0,0,708,31222,0,0,865,47405,0,0,327,7567,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,181:8:0 0,9,108:3:0 0,18,153:6:0 +17 86 . A 0 . DP=18;I16=17,0,0,0,692,29540,0,0,865,47405,0,0,326,7660,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,169:8:0 0,9,111:3:0 0,18,149:6:0 +17 87 . C 0 . DP=18;I16=17,0,0,0,683,29493,0,0,896,50164,0,0,326,7766,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,174:8:0 0,9,103:3:0 0,18,148:6:0 +17 88 . C 0 . DP=18;I16=17,0,0,0,703,31005,0,0,896,50164,0,0,326,7834,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,174:8:0 0,9,113:3:0 0,18,153:6:0 +17 89 . C 0 . DP=18;I16=17,0,0,0,697,30875,0,0,896,50164,0,0,326,7914,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,176:8:0 0,9,103:3:0 0,18,154:6:0 +17 90 . A 0 . DP=17;I16=16,0,0,0,668,29732,0,0,867,49323,0,0,326,7954,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,173:8:0 0,9,114:3:0 0,15,138:5:0 +17 91 . C 0 . DP=16;I16=15,0,0,0,613,26409,0,0,838,48482,0,0,327,8001,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,170:7:0 0,9,113:3:0 0,15,133:5:0 +17 92 . G 0 . DP=16;I16=15,0,0,0,499,18731,0,0,838,48482,0,0,328,8054,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,143:7:0 0,9,100:3:0 0,15,96:5:0 +17 93 . A 0 . DP=16;I16=15,0,0,0,635,28655,0,0,869,51241,0,0,329,8063,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,167:7:0 0,9,108:3:0 0,15,145:5:0 +17 94 . C 0 . DP=16;I16=15,0,0,0,607,25893,0,0,869,51241,0,0,331,8079,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,166:7:0 0,9,105:3:0 0,15,135:5:0 +17 95 . C 0 . DP=17;I16=15,0,0,0,615,26761,0,0,900,54000,0,0,306,7378,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,178:8:0 0,6,91:2:0 0,15,135:5:0 +17 96 . A 0 . DP=17;I16=16,0,0,0,625,26705,0,0,929,54841,0,0,332,7936,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,172:8:0 0,9,99:3:0 0,15,134:5:0 +17 97 . A 0 . DP=18;I16=17,0,0,0,675,29017,0,0,958,55682,0,0,333,7879,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,179:9:0 0,9,104:3:0 0,15,145:5:0 +17 98 . C 0 . DP=18;I16=17,0,0,0,655,27231,0,0,958,55682,0,0,333,7735,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,179:9:0 0,9,105:3:0 0,15,131:5:0 +17 99 . T 0 . DP=18;I16=17,0,0,0,720,32840,0,0,958,55682,0,0,333,7607,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,186:9:0 0,9,115:3:0 0,15,153:5:0 +17 100 . C 0 . DP=18;I16=17,0,0,0,688,29762,0,0,958,55682,0,0,332,7446,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,189:9:0 0,9,108:3:0 0,15,134:5:0 +17 101 . C 0 . DP=18;I16=17,0,0,0,650,27530,0,0,958,55682,0,0,331,7303,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,182:9:0 0,9,99:3:0 0,15,132:5:0 +17 102 . C 0 . DP=18;I16=17,0,0,0,695,30453,0,0,958,55682,0,0,330,7178,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,188:9:0 0,9,111:3:0 0,15,139:5:0 +17 103 . T 0 . DP=18;I16=16,0,0,0,692,31998,0,0,929,54841,0,0,323,7035,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,189:8:0 0,9,108:3:0 0,15,147:5:0 +17 104 . G 0 . DP=18;I16=15,0,0,0,611,26723,0,0,900,54000,0,0,295,6259,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,178:8:0 0,6,89:2:0 0,15,133:5:0 +17 105 . G 0 . DP=19;I16=17,0,0,0,604,23936,0,0,989,58441,0,0,317,6751,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,170:9:0 0,9,97:3:0 0,15,125:5:0 +17 106 . G 0 . DP=19;I16=17,0,0,0,644,26574,0,0,989,58441,0,0,299,6093,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,30,190:10:0 0,6,85:2:0 0,15,124:5:0 +17 107 . C 0 . DP=19;I16=17,0,0,0,694,30064,0,0,989,58441,0,0,313,6543,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,192:9:0 0,9,108:3:0 0,15,136:5:0 +17 108 . C 0 . DP=19;I16=17,0,0,0,692,30148,0,0,989,58441,0,0,310,6420,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,190:9:0 0,9,108:3:0 0,15,135:5:0 +17 109 . T 0 . DP=19;I16=17,0,0,0,741,34273,0,0,989,58441,0,0,307,6319,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,195:9:0 0,9,110:3:0 0,15,150:5:0 +17 110 . G 0 . DP=19;I16=17,0,0,0,704,31276,0,0,989,58441,0,0,304,6240,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,194:9:0 0,9,104:3:0 0,15,136:5:0 +17 111 . G 0 . DP=19;I16=16,0,0,0,584,24362,0,0,929,54841,0,0,272,5416,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,30,167:10:0 0,6,88:2:0 0,12,118:4:0 +17 112 . C 0 . DP=19;I16=17,0,0,0,680,29854,0,0,989,58441,0,0,296,6052,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,191:9:0 0,9,95:3:0 0,15,135:5:0 +17 113 . A 0 . DP=19;I16=16,0,0,0,645,28035,0,0,960,57600,0,0,266,5318,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,176:9:0 0,6,87:2:0 0,15,139:5:0 +17 114 . C 0 . DP=19;I16=17,0,0,0,674,28788,0,0,989,58441,0,0,286,5856,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,182:9:0 0,9,103:3:0 0,15,133:5:0 +17 115 . C 0 . DP=21;I16=18,0,0,0,708,30546,0,0,1049,62041,0,0,274,5490,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,30,189:10:0 0,6,89:2:0 0,18,147:6:0 +17 116 . A 0 . DP=21;I16=17,1,0,0,727,31755,0,0,1049,62041,0,0,253,5079,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,183:9:0 0,6,90:2:0 0,21,175:7:0 +17 117 . G 0 . DP=21;I16=17,1,0,0,723,31221,0,0,1049,62041,0,0,249,5019,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,186:9:0 0,6,86:2:0 0,21,177:7:0 +17 118 . G 0 . DP=20;I16=16,1,0,0,636,26574,0,0,958,55682,0,0,266,5426,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,175:9:0 0,3,60:1:0 0,21,162:7:0 +17 119 . G 0 . DP=19;I16=16,1,0,0,629,26439,0,0,958,55682,0,0,267,5553,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,175:8:0 0,6,73:2:0 0,21,160:7:0 +17 120 . A 0 . DP=19;I16=16,1,0,0,672,29188,0,0,958,55682,0,0,264,5518,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,175:8:0 0,6,83:2:0 0,21,171:7:0 +17 121 . G 0 . DP=19;I16=16,1,0,0,662,28460,0,0,958,55682,0,0,260,5454,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,181:8:0 0,6,80:2:0 0,21,168:7:0 +17 122 . C 0 . DP=20;I16=17,1,0,0,716,31224,0,0,1018,59282,0,0,256,5410,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,181:8:0 0,9,99:3:0 0,21,178:7:0 +17 123 . T 0 . DP=18;I16=15,1,0,0,661,29997,0,0,898,52082,0,0,255,5385,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,167:7:0 0,9,112:3:0 0,18,166:6:0 +17 124 . T 0 . DP=19;I16=17,1,0,0,626,24802,0,0,987,56523,0,0,279,6003,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,154:9:0 0,9,104:3:0 0,18,154:6:0 +17 125 . A 0 . DP=18;I16=15,1,0,0,611,25689,0,0,898,52082,0,0,254,5340,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,154:7:0 0,9,104:3:0 0,18,162:6:0 +17 126 . A 0 . DP=18;I16=16,1,0,0,648,27366,0,0,927,52923,0,0,279,5947,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,162:8:0 0,9,107:3:0 0,18,174:6:0 +17 127 . C 0 . DP=18;I16=16,1,0,0,646,26972,0,0,927,52923,0,0,279,5949,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,163:8:0 0,9,109:3:0 0,18,160:6:0 +17 128 . A 0 . DP=18;I16=16,1,0,0,673,28797,0,0,927,52923,0,0,279,5971,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,169:8:0 0,9,111:3:0 0,18,162:6:0 +17 129 . A 0 . DP=17;I16=15,1,0,0,645,27891,0,0,867,49323,0,0,280,6012,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,168:8:0 0,9,113:3:0 0,15,159:5:0 +17 130 . A 0 . DP=17;I16=15,1,0,0,641,27295,0,0,867,49323,0,0,281,6071,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,169:8:0 0,9,113:3:0 0,15,152:5:0 +17 131 . C 0 . DP=16;I16=14,1,0,0,606,25732,0,0,838,48482,0,0,256,5472,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,167:7:0 0,9,110:3:0 0,15,147:5:0 +17 132 . A 0 . DP=16;I16=14,1,0,0,627,27579,0,0,838,48482,0,0,256,5514,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,169:7:0 0,9,110:3:0 0,15,151:5:0 +17 133 . T 0 . DP=15;I16=13,2,0,0,584,22816,0,0,838,48482,0,0,282,6196,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,163:7:0 0,9,105:3:0 0,15,150:5:0 +17 134 . C 0 . DP=15;I16=13,2,0,0,607,24653,0,0,838,48482,0,0,283,6267,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,177:7:0 0,9,105:3:0 0,15,152:5:0 +17 135 . T 0 . DP=15;I16=13,2,0,0,600,24178,0,0,838,48482,0,0,284,6352,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,173:7:0 0,9,106:3:0 0,15,156:5:0 +17 136 . G 0 . DP=15;I16=13,2,0,0,574,22258,0,0,838,48482,0,0,286,6450,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,172:7:0 0,9,105:3:0 0,15,134:5:0 +17 137 . T 0 . DP=15;I16=13,2,0,0,563,21377,0,0,838,48482,0,0,289,6561,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,160:7:0 0,9,104:3:0 0,15,139:5:0 +17 138 . C 0 . DP=15;I16=13,2,0,0,584,23088,0,0,838,48482,0,0,291,6637,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,172:7:0 0,9,108:3:0 0,15,142:5:0 +17 139 . C 0 . DP=15;I16=13,2,0,0,554,20790,0,0,838,48482,0,0,292,6680,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,161:7:0 0,9,106:3:0 0,15,143:5:0 +17 140 . A 0 . DP=15;I16=13,2,0,0,583,22789,0,0,838,48482,0,0,292,6690,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,163:7:0 0,9,107:3:0 0,15,153:5:0 +17 141 . G 0 . DP=14;I16=12,2,0,0,534,20750,0,0,778,44882,0,0,292,6664,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,158:6:0 0,9,108:3:0 0,15,142:5:0 +17 142 . C 0 . DP=14;I16=12,2,0,0,503,18593,0,0,778,44882,0,0,292,6650,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,157:6:0 0,9,97:3:0 0,15,129:5:0 +17 143 . G 0 . DP=14;I16=11,2,0,0,415,13657,0,0,718,41282,0,0,285,6599,0,0;QS=3,0;MQSB=0.590909;MQ0F=0 PL:DP:DV 0,18,128:6:0 0,9,95:3:0 0,12,97:4:0 +17 144 . A 0 . DP=14;I16=12,2,0,0,519,19725,0,0,778,44882,0,0,291,6609,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,152:6:0 0,9,105:3:0 0,15,129:5:0 +17 145 . A 0 . DP=14;I16=12,2,0,0,527,20289,0,0,778,44882,0,0,290,6584,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,153:6:0 0,9,106:3:0 0,15,138:5:0 +17 146 . T 0 . DP=14;I16=12,2,0,0,514,19484,0,0,778,44882,0,0,289,6573,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,152:6:0 0,9,103:3:0 0,15,128:5:0 +17 147 . A 0 . DP=14;I16=12,2,0,0,515,19213,0,0,778,44882,0,0,288,6576,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,150:6:0 0,9,99:3:0 0,15,140:5:0 +17 148 . C 0 . DP=14;I16=12,2,0,0,541,21019,0,0,778,44882,0,0,286,6542,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,157:6:0 0,9,106:3:0 0,15,146:5:0 +17 149 . C 0 . DP=14;I16=12,2,0,0,512,19326,0,0,778,44882,0,0,283,6471,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,148:6:0 0,9,109:3:0 0,15,140:5:0 +17 150 . T 0 . DP=13;I16=11,2,0,0,511,20251,0,0,749,44041,0,0,280,6362,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,153:6:0 0,6,84:2:0 0,15,152:5:0 +17 151 . G 0 . DP=13;I16=11,2,0,0,506,19826,0,0,749,44041,0,0,277,6263,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,157:6:0 0,6,84:2:0 0,15,144:5:0 +17 152 . C 0 . DP=14;I16=12,2,0,0,543,21283,0,0,809,47641,0,0,274,6174,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,168:7:0 0,6,84:2:0 0,15,146:5:0 +17 153 . A 0 . DP=14;I16=12,2,0,0,536,20594,0,0,809,47641,0,0,272,6096,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,156:7:0 0,6,81:2:0 0,15,153:5:0 +17 154 . T 0 . DP=14;I16=12,2,0,0,523,20051,0,0,809,47641,0,0,270,6030,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,159:7:0 0,6,83:2:0 0,15,139:5:0 +17 155 . C 0 . DP=14;I16=12,2,0,0,542,21254,0,0,809,47641,0,0,268,5976,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,172:7:0 0,6,85:2:0 0,15,139:5:0 +17 156 . C 0 . DP=14;I16=12,2,0,0,536,20884,0,0,809,47641,0,0,266,5934,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,163:7:0 0,6,84:2:0 0,15,150:5:0 +17 157 . C 0 . DP=14;I16=12,2,0,0,555,22081,0,0,809,47641,0,0,264,5904,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,169:7:0 0,6,85:2:0 0,15,149:5:0 +17 158 . T 0 . DP=14;I16=12,2,0,0,568,23154,0,0,809,47641,0,0,262,5886,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,170:7:0 0,6,84:2:0 0,15,159:5:0 +17 159 . A 0 . DP=15;I16=12,2,0,0,519,19467,0,0,809,47641,0,0,260,5880,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,157:7:0 0,6,83:2:0 0,15,135:5:0 +17 160 . G 0 . DP=15;I16=13,2,0,0,547,20633,0,0,869,51241,0,0,259,5887,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,165:7:0 0,6,85:2:0 0,18,139:6:0 +17 161 . A 0 . DP=15;I16=13,2,0,0,568,21610,0,0,869,51241,0,0,258,5908,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,157:7:0 0,6,83:2:0 0,18,162:6:0 +17 162 . A 0 . DP=15;I16=13,2,0,0,557,21139,0,0,869,51241,0,0,255,5843,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,147:7:0 0,6,87:2:0 0,18,167:6:0 +17 163 . G 0 . DP=14;I16=12,2,0,0,503,18645,0,0,809,47641,0,0,253,5791,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,153:7:0 0,6,79:2:0 0,15,138:5:0 +17 164 . T 0 . DP=14;I16=12,2,0,0,460,15968,0,0,809,47641,0,0,252,5750,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,131:6:0 0,6,79:2:0 0,18,136:6:0 +17 165 . G 0 . DP=14;I16=10,2,0,0,456,17460,0,0,689,40441,0,0,226,5094,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,149:6:0 0,6,80:2:0 0,12,122:4:0 +17 166 . A 0 . DP=14;I16=11,2,0,0,496,19138,0,0,749,44041,0,0,227,5077,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,145:6:0 0,6,82:2:0 0,15,148:5:0 +17 167 . A 0 . DP=14;I16=11,2,0,0,477,17851,0,0,749,44041,0,0,227,5071,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,132:6:0 0,6,86:2:0 0,15,147:5:0 +17 168 . G 0 . DP=14;I16=12,2,0,0,481,18015,0,0,809,47641,0,0,252,5702,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,145:6:0 0,6,82:2:0 0,18,140:6:0 +17 169 . C 0 . DP=13;I16=10,2,0,0,402,14224,0,0,689,40441,0,0,227,5045,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,15,106:5:0 0,6,76:2:0 0,15,145:5:0 +17 170 . C 0 . DP=13;I16=11,2,0,0,447,16383,0,0,749,44041,0,0,251,5601,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,15,128:5:0 0,6,80:2:0 0,18,143:6:0 +17 171 . A 0 . DP=13;I16=11,2,0,0,500,19366,0,0,749,44041,0,0,250,5546,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,15,134:5:0 0,6,81:2:0 0,18,166:6:0 +17 172 . C 0 . DP=13;I16=10,2,0,0,439,16395,0,0,689,40441,0,0,241,5441,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,15,138:5:0 0,6,75:2:0 0,15,129:5:0 +17 173 . C 0 . DP=13;I16=11,2,0,0,435,15225,0,0,749,44041,0,0,248,5478,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,15,121:5:0 0,6,76:2:0 0,18,146:6:0 +17 174 . G 0 . DP=13;I16=11,1,0,0,351,10685,0,0,689,40441,0,0,238,5364,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,111:5:0 0,3,27:1:0 0,18,117:6:0 +17 175 . C 0 . DP=14;I16=13,1,0,0,511,19161,0,0,809,47641,0,0,249,5463,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,143:6:0 0,3,41:1:0 0,21,175:7:0 +17 176 . C 0 . DP=14;I16=13,1,0,0,489,17733,0,0,809,47641,0,0,251,5477,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,146:6:0 0,3,44:1:0 0,21,152:7:0 +17 177 . C 0 . DP=14;I16=13,1,0,0,488,17328,0,0,809,47641,0,0,253,5507,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,138:6:0 0,3,44:1:0 0,21,158:7:0 +17 178 . A 0 . DP=14;I16=13,1,0,0,519,19485,0,0,809,47641,0,0,254,5502,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,147:6:0 0,3,42:1:0 0,21,172:7:0 +17 179 . A 0 . DP=14;I16=13,1,0,0,478,17278,0,0,809,47641,0,0,255,5511,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,134:6:0 0,3,44:1:0 0,21,170:7:0 +17 180 . A 0 . DP=14;I16=12,1,0,0,425,14653,0,0,749,44041,0,0,250,5498,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,126:6:0 0,3,43:1:0 0,18,148:6:0 +17 181 . G 0 . DP=14;I16=11,1,0,0,450,17152,0,0,689,40441,0,0,233,5233,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,156:6:0 0,3,41:1:0 0,15,138:5:0 +17 182 . A 0 . DP=15;I16=14,1,0,0,515,18235,0,0,869,51241,0,0,258,5622,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,150:7:0 0,3,43:1:0 0,21,159:7:0 +17 183 . C 0 . DP=15;I16=13,1,0,0,483,17419,0,0,809,47641,0,0,235,5063,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,159:7:0 0,3,40:1:0 0,18,139:6:0 +17 184 . A 0 . DP=15;I16=14,1,0,0,535,19667,0,0,869,51241,0,0,262,5770,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,158:7:0 0,3,41:1:0 0,21,163:7:0 +17 185 . C 0 . DP=15;I16=13,1,0,0,487,17295,0,0,809,47641,0,0,238,5192,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,150:7:0 0,3,38:1:0 0,18,160:6:0 +17 186 . G 0 . DP=15;I16=12,1,0,0,381,11429,0,0,749,44041,0,0,239,5253,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,117:6:0 0,3,32:1:0 0,18,124:6:0 +17 187 . C 0 . DP=14;I16=13,1,0,0,511,18979,0,0,809,47641,0,0,266,5952,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,147:6:0 0,3,38:1:0 0,21,172:7:0 +17 188 . C 0 . DP=14;I16=13,1,0,0,496,18042,0,0,809,47641,0,0,267,5989,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,147:6:0 0,3,37:1:0 0,21,162:7:0 +17 189 . C 0 . DP=15;I16=13,2,0,0,552,20504,0,0,838,48482,0,0,268,6040,0,0;QS=3,0;MQSB=0;MQ0F=0 PL:DP:DV 0,18,152:6:0 0,6,67:2:0 0,21,167:7:0 +17 190 . A 0 . DP=15;I16=12,2,0,0,500,18230,0,0,778,44882,0,0,243,5381,0,0;QS=3,0;MQSB=0;MQ0F=0 PL:DP:DV 0,18,138:6:0 0,6,68:2:0 0,18,159:6:0 +17 191 . T 0 . DP=15;I16=13,2,0,0,534,19276,0,0,838,48482,0,0,267,5939,0,0;QS=3,0;MQSB=0;MQ0F=0 PL:DP:DV 0,18,143:6:0 0,6,67:2:0 0,21,169:7:0 +17 192 . G 0 . DP=15;I16=13,2,0,0,499,17439,0,0,838,48482,0,0,266,5890,0,0;QS=3,0;MQSB=0;MQ0F=0 PL:DP:DV 0,18,143:6:0 0,6,67:2:0 0,21,151:7:0 +17 193 . T 0 . DP=15;I16=13,2,0,0,505,17811,0,0,838,48482,0,0,265,5859,0,0;QS=3,0;MQSB=0;MQ0F=0 PL:DP:DV 0,18,140:6:0 0,6,63:2:0 0,21,157:7:0 +17 194 . C 0 . DP=14;I16=12,2,0,0,467,16569,0,0,778,44882,0,0,265,5845,0,0;QS=3,0;MQSB=0;MQ0F=0 PL:DP:DV 0,18,142:6:0 0,6,67:2:0 0,18,145:6:0 +17 195 . C 0 . DP=14;I16=11,3,0,0,503,18647,0,0,747,42123,0,0,266,5846,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,18,159:6:0 0,6,71:2:0 0,18,160:6:0 +17 196 . A 0 . DP=14;I16=11,3,0,0,482,17400,0,0,747,42123,0,0,268,5862,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,18,166:6:0 0,6,69:2:0 0,18,138:6:0 +17 197 . G 0 . DP=14;I16=11,3,0,0,481,17391,0,0,747,42123,0,0,270,5894,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,18,164:6:0 0,6,68:2:0 0,18,134:6:0 +17 198 . C 0 . DP=14;I16=11,3,0,0,539,20957,0,0,747,42123,0,0,271,5893,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,18,172:6:0 0,6,70:2:0 0,18,164:6:0 +17 199 . T 0 . DP=14;I16=11,3,0,0,505,19197,0,0,747,42123,0,0,271,5861,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,18,162:6:0 0,6,73:2:0 0,18,154:6:0 +17 200 . T 0 . DP=15;I16=11,4,0,0,544,19918,0,0,776,42964,0,0,270,5798,0,0;QS=3,0;MQSB=0.0161635;MQ0F=0 PL:DP:DV 0,18,161:6:0 0,9,89:3:0 0,18,154:6:0 +17 201 . A 0 . DP=16;I16=12,4,0,0,568,20416,0,0,836,46564,0,0,269,5703,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,171:7:0 0,9,89:3:0 0,18,157:6:0 +17 202 . A 0 . DP=16;I16=12,4,0,0,566,20590,0,0,836,46564,0,0,269,5627,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,178:7:0 0,9,84:3:0 0,18,163:6:0 +17 203 . C 0 . DP=16;I16=12,4,0,0,557,20119,0,0,836,46564,0,0,269,5571,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,166:7:0 0,9,90:3:0 0,18,153:6:0 +17 204 . C 0 . DP=16;I16=12,4,0,0,591,22379,0,0,836,46564,0,0,269,5535,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,173:7:0 0,9,91:3:0 0,18,163:6:0 +17 205 . T 0 . DP=16;I16=12,4,0,0,635,25281,0,0,836,46564,0,0,269,5519,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,188:7:0 0,9,95:3:0 0,18,173:6:0 +17 206 . G 0 . DP=16;I16=12,4,0,0,577,21337,0,0,836,46564,0,0,269,5523,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,180:7:0 0,9,89:3:0 0,18,143:6:0 +17 207 . C 0 . DP=16;I16=12,4,0,0,574,21076,0,0,836,46564,0,0,269,5547,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,179:7:0 0,9,93:3:0 0,18,151:6:0 +17 208 . A 0 . DP=16;I16=12,4,0,0,576,21486,0,0,836,46564,0,0,268,5540,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,184:7:0 0,9,93:3:0 0,18,154:6:0 +17 209 . T 0 . DP=16;I16=12,4,0,0,567,20475,0,0,836,46564,0,0,267,5551,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,173:7:0 0,9,91:3:0 0,18,146:6:0 +17 210 . C 0 . DP=16;I16=12,4,0,0,577,21109,0,0,836,46564,0,0,266,5580,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,185:7:0 0,9,92:3:0 0,18,151:6:0 +17 211 . C 0 . DP=16;I16=12,4,0,0,563,20227,0,0,836,46564,0,0,265,5627,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,172:7:0 0,9,92:3:0 0,18,153:6:0 +17 212 . C 0 . DP=16;I16=12,4,0,0,589,22179,0,0,836,46564,0,0,263,5643,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,181:7:0 0,9,92:3:0 0,18,152:6:0 +17 213 . T 0 . DP=16;I16=12,4,0,0,598,22838,0,0,836,46564,0,0,262,5678,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,181:7:0 0,9,95:3:0 0,18,165:6:0 +17 214 . A 0 . DP=16;I16=11,4,0,0,529,19401,0,0,776,42964,0,0,240,5248,0,0;QS=3,0;MQSB=0.0161635;MQ0F=0 PL:DP:DV 0,21,176:7:0 0,9,92:3:0 0,15,118:5:0 +17 215 . G 0 . DP=15;I16=12,3,0,0,521,19073,0,0,807,45723,0,0,262,5754,0,0;QS=3,0;MQSB=0.0342181;MQ0F=0 PL:DP:DV 0,21,185:7:0 0,9,90:3:0 0,15,105:5:0 +17 216 . A 0 . DP=14;I16=10,3,0,0,464,16900,0,0,687,38523,0,0,238,5166,0,0;QS=3,0;MQSB=0.040184;MQ0F=0 PL:DP:DV 0,21,173:7:0 0,9,92:3:0 0,9,81:3:0 +17 217 . A 0 . DP=14;I16=11,3,0,0,515,19433,0,0,747,42123,0,0,264,5842,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,21,181:7:0 0,9,90:3:0 0,12,97:4:0 +17 218 . G 0 . DP=14;I16=11,3,0,0,507,18957,0,0,747,42123,0,0,265,5907,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,21,178:7:0 0,9,90:3:0 0,12,110:4:0 +17 219 . T 0 . DP=14;I16=11,3,0,0,470,16286,0,0,747,42123,0,0,266,5986,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,21,173:7:0 0,9,88:3:0 0,12,89:4:0 +17 220 . G 0 . DP=14;I16=10,3,0,0,485,18307,0,0,687,38523,0,0,242,5454,0,0;QS=3,0;MQSB=0.040184;MQ0F=0 PL:DP:DV 0,21,188:7:0 0,9,88:3:0 0,9,80:3:0 +17 221 . A 0 . DP=14;I16=11,3,0,0,487,17615,0,0,747,42123,0,0,267,6135,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,21,176:7:0 0,9,88:3:0 0,12,101:4:0 +17 222 . A 0 . DP=14;I16=10,3,0,0,465,17367,0,0,687,38523,0,0,242,5578,0,0;QS=3,0;MQSB=0.040184;MQ0F=0 PL:DP:DV 0,21,186:7:0 0,9,85:3:0 0,9,69:3:0 +17 223 . G 0 . DP=13;I16=9,3,0,0,405,14327,0,0,627,34923,0,0,243,5657,0,0;QS=3,0;MQSB=0.0443614;MQ0F=0 PL:DP:DV 0,18,168:6:0 0,6,53:2:0 0,12,81:4:0 +17 224 . G 0 . DP=12;I16=9,3,0,0,379,12759,0,0,627,34923,0,0,270,6370,0,0;QS=3,0;MQSB=0.0443614;MQ0F=0 PL:DP:DV 0,18,168:6:0 0,6,50:2:0 0,12,70:4:0 +17 225 . C 0 . DP=12;I16=8,3,0,0,382,13896,0,0,567,31323,0,0,261,6345,0,0;QS=3,0;MQSB=0.0497871;MQ0F=0 PL:DP:DV 0,18,165:6:0 0,6,48:2:0 0,9,83:3:0 +17 226 . A 0 . DP=13;I16=8,3,0,0,381,13669,0,0,567,31323,0,0,248,5894,0,0;QS=3,0;MQSB=0.0497871;MQ0F=0 PL:DP:DV 0,18,166:6:0 0,6,53:2:0 0,9,84:3:0 +17 227 . C 0 . DP=13;I16=8,4,0,0,406,14306,0,0,596,32164,0,0,267,6253,0,0;QS=3,0;MQSB=0.0249144;MQ0F=0 PL:DP:DV 0,21,190:7:0 0,6,53:2:0 0,9,73:3:0 +17 228 . C 0 . DP=13;I16=9,4,0,0,417,14381,0,0,656,35764,0,0,292,6884,0,0;QS=3,0;MQSB=0.0211283;MQ0F=0 PL:DP:DV 0,21,187:7:0 0,6,45:2:0 0,12,96:4:0 +17 229 . G 0 . DP=13;I16=9,3,0,0,358,11424,0,0,627,34923,0,0,270,6414,0,0;QS=3,0;MQSB=0.0443614;MQ0F=0 PL:DP:DV 0,18,136:6:0 0,6,53:2:0 0,12,70:4:0 +17 230 . C 0 . DP=13;I16=9,4,0,0,461,16861,0,0,656,35764,0,0,292,6920,0,0;QS=3,0;MQSB=0.0211283;MQ0F=0 PL:DP:DV 0,21,186:7:0 0,6,53:2:0 0,12,100:4:0 +17 231 . C 0 . DP=13;I16=7,4,0,0,414,15832,0,0,536,28564,0,0,247,5925,0,0;QS=3,0;MQSB=0.0401934;MQ0F=0 PL:DP:DV 0,18,184:6:0 0,6,53:2:0 0,9,82:3:0 +17 232 . C 0 . DP=14;I16=9,4,0,0,471,17371,0,0,656,35764,0,0,267,6363,0,0;QS=3,0;MQSB=0.0211283;MQ0F=0 PL:DP:DV 0,21,198:7:0 0,6,53:2:0 0,12,101:4:0 +17 233 . A 0 . DP=14;I16=10,4,0,0,496,18142,0,0,716,39364,0,0,292,6984,0,0;QS=3,0;MQSB=0.0183156;MQ0F=0 PL:DP:DV 0,21,192:7:0 0,6,53:2:0 0,15,119:5:0 +17 234 . A 0 . DP=14;I16=10,4,0,0,502,18390,0,0,716,39364,0,0,292,6988,0,0;QS=3,0;MQSB=0.0183156;MQ0F=0 PL:DP:DV 0,21,185:7:0 0,6,53:2:0 0,15,123:5:0 +17 235 . A 0 . DP=14;I16=9,4,0,0,476,17652,0,0,656,35764,0,0,267,6375,0,0;QS=3,0;MQSB=0.0211283;MQ0F=0 PL:DP:DV 0,21,186:7:0 0,6,53:2:0 0,12,111:4:0 +17 236 . G 0 . DP=15;I16=11,4,0,0,501,17481,0,0,776,42964,0,0,290,6924,0,0;QS=3,0;MQSB=0.0161635;MQ0F=0 PL:DP:DV 0,24,206:8:0 0,6,53:2:0 0,15,103:5:0 +17 237 . A 0 . DP=14;I16=9,4,0,0,465,16877,0,0,656,35764,0,0,266,6282,0,0;QS=3,0;MQSB=0.0211283;MQ0F=0 PL:DP:DV 0,24,206:8:0 0,6,53:2:0 0,9,92:3:0 +17 238 . C 0 . DP=14;I16=10,4,0,0,482,17238,0,0,716,39364,0,0,292,6900,0,0;QS=3,0;MQSB=0.0183156;MQ0F=0 PL:DP:DV 0,24,211:8:0 0,6,53:2:0 0,12,82:4:0 +17 239 . A 0 . DP=15;I16=10,5,0,0,525,19155,0,0,776,42964,0,0,292,6852,0,0;QS=3,0;MQSB=0.0497871;MQ0F=0 PL:DP:DV 0,27,223:9:0 0,6,50:2:0 0,12,108:4:0 +17 240 . C 0 . DP=15;I16=10,5,0,0,512,17930,0,0,776,42964,0,0,292,6764,0,0;QS=3,0;MQSB=0.0497871;MQ0F=0 PL:DP:DV 0,27,220:9:0 0,6,53:2:0 0,12,106:4:0 +17 241 . G 0 . DP=15;I16=9,5,0,0,444,14636,0,0,716,39364,0,0,269,6159,0,0;QS=3,0;MQSB=0.0561348;MQ0F=0 PL:DP:DV 0,27,203:9:0 0,6,53:2:0 0,9,59:3:0 +17 242 . C 0 . DP=15;I16=10,5,0,0,555,21177,0,0,776,42964,0,0,292,6624,0,0;QS=3,0;MQSB=0.0497871;MQ0F=0 PL:DP:DV 0,27,242:9:0 0,6,53:2:0 0,12,94:4:0 +17 243 . C 0 . DP=16;I16=9,5,0,0,523,19737,0,0,716,39364,0,0,284,6508,0,0;QS=3,0;MQSB=0.0561348;MQ0F=0 PL:DP:DV 0,24,220:8:0 0,6,53:2:0 0,12,104:4:0 +17 244 . C 0 . DP=16;I16=10,6,0,0,620,24272,0,0,805,43805,0,0,298,6568,0,0;QS=3,0;MQSB=0.0253122;MQ0F=0 PL:DP:DV 0,27,245:9:0 0,9,72:3:0 0,12,106:4:0 +17 245 . A 0 . DP=17;I16=10,7,0,0,649,24843,0,0,865,47405,0,0,299,6553,0,0;QS=3,0;MQSB=0.0509867;MQ0F=0 PL:DP:DV 0,27,236:9:0 0,12,93:4:0 0,12,115:4:0 +17 246 . T 0 . DP=18;I16=10,8,0,0,649,23833,0,0,894,48246,0,0,301,6553,0,0;QS=3,0;MQSB=0.0286491;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,12,94:4:0 0,12,98:4:0 +17 247 . G 0 . DP=18;I16=10,8,0,0,642,23610,0,0,894,48246,0,0,304,6570,0,0;QS=3,0;MQSB=0.0286491;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,12,83:4:0 0,12,103:4:0 +17 248 . T 0 . DP=18;I16=10,8,0,0,636,22944,0,0,894,48246,0,0,307,6605,0,0;QS=3,0;MQSB=0.0286491;MQ0F=0 PL:DP:DV 0,30,234:10:0 0,12,86:4:0 0,12,114:4:0 +17 249 . C 0 . DP=18;I16=10,8,0,0,656,24846,0,0,894,48246,0,0,310,6658,0,0;QS=3,0;MQSB=0.0286491;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,12,79:4:0 0,12,112:4:0 +17 250 . C 0 . DP=19;I16=10,9,0,0,694,26160,0,0,923,49087,0,0,311,6631,0,0;QS=3,0;MQSB=0.0168512;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,12,89:4:0 0,15,142:5:0 +17 251 . A 0 . DP=19;I16=9,9,0,0,688,26506,0,0,863,45487,0,0,313,6627,0,0;QS=3,0;MQSB=0.0208913;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,12,97:4:0 0,15,148:5:0 +17 252 . G 0 . DP=18;I16=8,9,0,0,641,24631,0,0,803,41887,0,0,304,6502,0,0;QS=3,0;MQSB=0.026526;MQ0F=0 PL:DP:DV 0,27,243:9:0 0,12,91:4:0 0,12,121:4:0 +17 253 . C 0 . DP=19;I16=9,10,0,0,705,26921,0,0,892,46328,0,0,319,6687,0,0;QS=3,0;MQSB=0.0132999;MQ0F=0 PL:DP:DV 0,27,247:9:0 0,12,86:4:0 0,18,155:6:0 +17 254 . T 0 . DP=20;I16=10,9,0,0,719,27517,0,0,892,46328,0,0,314,6670,0,0;QS=3,0;MQSB=0.00482795;MQ0F=0 PL:DP:DV 0,30,254:10:0 0,9,72:3:0 0,18,164:6:0 +17 255 . T 0 . DP=21;I16=11,10,0,0,750,27076,0,0,1012,53528,0,0,328,6840,0,0;QS=3,0;MQSB=0.00822975;MQ0F=0 PL:DP:DV 0,33,241:11:0 0,12,95:4:0 0,18,161:6:0 +17 256 . A 0 . DP=22;I16=11,11,0,0,811,30063,0,0,1049,54897,0,0,334,6956,0,0;QS=3,0;MQSB=0.00507916;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,110:5:0 0,18,166:6:0 +17 257 . T 0 . DP=22;I16=11,11,0,0,814,30420,0,0,1049,54897,0,0,341,7101,0,0;QS=3,0;MQSB=0.00507916;MQ0F=0 PL:DP:DV 0,33,247:11:0 0,15,113:5:0 0,18,168:6:0 +17 258 . T 0 . DP=22;I16=11,11,0,0,791,28943,0,0,1049,54897,0,0,347,7225,0,0;QS=3,0;MQSB=0.00507916;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,15,116:5:0 0,18,155:6:0 +17 259 . C 0 . DP=22;I16=11,10,0,0,785,29809,0,0,1020,54056,0,0,332,6936,0,0;QS=3,0;MQSB=0.00822975;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,90:4:0 0,18,170:6:0 +17 260 . T 0 . DP=21;I16=10,11,0,0,829,32899,0,0,989,51297,0,0,360,7556,0,0;QS=3,0;MQSB=0.00660016;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,118:5:0 0,15,156:5:0 +17 261 . G 0 . DP=21;I16=10,11,0,0,735,27379,0,0,989,51297,0,0,367,7761,0,0;QS=3,0;MQSB=0.00660016;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,15,111:5:0 0,15,122:5:0 +17 262 . C 0 . DP=22;I16=10,12,0,0,806,30278,0,0,1049,54897,0,0,373,7941,0,0;QS=3,0;MQSB=0.0122507;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,99:5:0 0,18,164:6:0 +17 263 . C 0 . DP=22;I16=10,12,0,0,799,29717,0,0,1049,54897,0,0,380,8146,0,0;QS=3,0;MQSB=0.0122507;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,98:5:0 0,18,168:6:0 +17 264 . C 0 . DP=22;I16=10,12,0,0,821,31325,0,0,1049,54897,0,0,386,8326,0,0;QS=3,0;MQSB=0.0122507;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,104:5:0 0,18,172:6:0 +17 265 . A 0 . DP=21;I16=9,12,0,0,800,31906,0,0,989,51297,0,0,390,8380,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,114:5:0 0,15,129:5:0 +17 266 . G 0 . DP=21;I16=9,11,0,0,747,28155,0,0,960,50456,0,0,369,7833,0,0;QS=3,0;MQSB=0.0237479;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,97:4:0 0,15,138:5:0 +17 267 . T 0 . DP=21;I16=9,11,0,0,739,27465,0,0,960,50456,0,0,373,7935,0,0;QS=3,0;MQSB=0.0237479;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,12,101:4:0 0,15,149:5:0 +17 268 . T 0 . DP=21;I16=9,12,0,0,748,27708,0,0,989,51297,0,0,402,8686,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:DV 0,33,238:11:0 0,15,110:5:0 0,15,156:5:0 +17 269 . C 0 . DP=22;I16=9,12,0,0,764,28632,0,0,989,51297,0,0,381,8211,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,91:4:0 0,15,154:5:0 +17 270 . C 0 . DP=22;I16=9,12,0,0,758,28146,0,0,989,51297,0,0,385,8337,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,96:4:0 0,15,143:5:0 +17 271 . T 0 . DP=22;I16=9,13,0,0,847,32935,0,0,1018,52138,0,0,413,9065,0,0;QS=3,0;MQSB=0.0109431;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,113:5:0 0,15,152:5:0 +17 272 . C 0 . DP=22;I16=9,12,0,0,809,31413,0,0,989,51297,0,0,390,8518,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,96:4:0 0,15,149:5:0 +17 273 . T 0 . DP=22;I16=9,12,0,0,798,30664,0,0,989,51297,0,0,392,8620,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,95:4:0 0,15,161:5:0 +17 274 . C 0 . DP=22;I16=9,12,0,0,763,28177,0,0,989,51297,0,0,394,8746,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,101:4:0 0,15,144:5:0 +17 275 . C 0 . DP=20;I16=7,13,0,0,768,29994,0,0,898,44938,0,0,423,9519,0,0;QS=3,0;MQSB=0.0213617;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,114:5:0 0,12,122:4:0 +17 276 . A 0 . DP=20;I16=7,13,0,0,805,32931,0,0,898,44938,0,0,424,9538,0,0;QS=3,0;MQSB=0.0213617;MQ0F=0 PL:DP:DV 0,33,253:11:0 0,15,122:5:0 0,12,124:4:0 +17 277 . G 0 . DP=20;I16=7,13,0,0,764,29732,0,0,898,44938,0,0,425,9579,0,0;QS=3,0;MQSB=0.0213617;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,114:5:0 0,12,121:4:0 +17 278 . A 0 . DP=21;I16=6,14,0,0,722,26452,0,0,867,42179,0,0,415,9521,0,0;QS=3,0;MQSB=0.0246228;MQ0F=0 PL:DP:DV 0,30,238:10:0 0,18,123:6:0 0,12,121:4:0 +17 279 . A 0 . DP=22;I16=7,15,0,0,786,28694,0,0,956,46620,0,0,427,9677,0,0;QS=3,0;MQSB=0.0124927;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,123:6:0 0,12,122:4:0 +17 280 . A 0 . DP=22;I16=7,15,0,0,815,31561,0,0,956,46620,0,0,428,9684,0,0;QS=3,0;MQSB=0.0124927;MQ0F=0 PL:DP:DV 0,36,253:12:0 0,18,130:6:0 0,12,129:4:0 +17 281 . G 0 . DP=22;I16=7,15,0,0,820,31416,0,0,956,46620,0,0,428,9662,0,0;QS=3,0;MQSB=0.0124927;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,122:6:0 0,12,123:4:0 +17 282 . G 0 . DP=22;I16=7,15,0,0,806,30420,0,0,956,46620,0,0,427,9609,0,0;QS=3,0;MQSB=0.0124927;MQ0F=0 PL:DP:DV 0,36,253:12:0 0,18,124:6:0 0,12,119:4:0 +17 283 . C 0 . DP=23;I16=7,15,0,0,827,31785,0,0,956,46620,0,0,426,9574,0,0;QS=3,0;MQSB=0.0124927;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,125:6:0 0,12,122:4:0 +17 284 . T 0 . DP=23;I16=7,16,0,0,901,35479,0,0,1016,50220,0,0,431,9593,0,0;QS=3,0;MQSB=0.0194969;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,126:6:0 0,15,144:5:0 +17 285 . G 0 . DP=23;I16=7,16,0,0,860,32856,0,0,1016,50220,0,0,431,9607,0,0;QS=3,0;MQSB=0.0194969;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,119:6:0 0,15,132:5:0 +17 286 . C 0 . DP=24;I16=8,16,0,0,875,32883,0,0,1076,53820,0,0,431,9641,0,0;QS=3,0;MQSB=0.0132999;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,150:7:0 0,15,134:5:0 +17 287 . A 0 . DP=25;I16=9,16,0,0,895,32957,0,0,1136,57420,0,0,432,9696,0,0;QS=3,0;MQSB=0.00934348;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,178:8:0 0,15,133:5:0 +17 288 . T 0 . DP=25;I16=9,16,0,0,931,35011,0,0,1136,57420,0,0,432,9674,0,0;QS=3,0;MQSB=0.00934348;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,184:8:0 0,15,146:5:0 +17 289 . G 0 . DP=25;I16=9,16,0,0,939,36117,0,0,1136,57420,0,0,432,9676,0,0;QS=3,0;MQSB=0.00934348;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,185:8:0 0,15,136:5:0 +17 290 . G 0 . DP=23;I16=8,15,0,0,805,29157,0,0,1047,52979,0,0,433,9651,0,0;QS=3,0;MQSB=0.0177152;MQ0F=0 PL:DP:DV 0,33,240:11:0 0,21,164:7:0 0,15,126:5:0 +17 291 . T 0 . DP=24;I16=8,15,0,0,840,31616,0,0,1047,52979,0,0,421,9479,0,0;QS=3,0;MQSB=0.0177152;MQ0F=0 PL:DP:DV 0,33,244:11:0 0,21,168:7:0 0,15,136:5:0 +17 292 . T 0 . DP=25;I16=9,16,0,0,888,32274,0,0,1167,60179,0,0,436,9668,0,0;QS=3,0;MQSB=0.0197089;MQ0F=0 PL:DP:DV 0,33,253:11:0 0,24,181:8:0 0,18,156:6:0 +17 293 . G 0 . DP=26;I16=10,15,0,0,934,35232,0,0,1167,60179,0,0,424,9488,0,0;QS=3,0;MQSB=0.0095249;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,196:8:0 0,15,145:5:0 +17 294 . A 0 . DP=26;I16=10,16,0,0,931,33937,0,0,1227,63779,0,0,443,9785,0,0;QS=3,0;MQSB=0.0149748;MQ0F=0 PL:DP:DV 0,36,252:12:0 0,24,201:8:0 0,18,161:6:0 +17 295 . C 0 . DP=25;I16=10,14,0,0,897,33973,0,0,1169,62097,0,0,430,9544,0,0;QS=3,0;MQSB=0.0310726;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,180:7:0 0,18,159:6:0 +17 296 . A 0 . DP=25;I16=10,15,0,0,874,31846,0,0,1198,62938,0,0,451,9905,0,0;QS=3,0;MQSB=0.0213617;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,169:8:0 0,18,169:6:0 +17 297 . C 0 . DP=25;I16=9,15,0,0,901,34305,0,0,1138,59338,0,0,445,9901,0,0;QS=3,0;MQSB=0.0273237;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,174:7:0 0,18,161:6:0 +17 298 . A 0 . DP=26;I16=11,15,0,0,936,34652,0,0,1258,66538,0,0,459,10121,0,0;QS=3,0;MQSB=0.017008;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,184:8:0 0,21,191:7:0 +17 299 . C 0 . DP=27;I16=11,15,0,0,971,36863,0,0,1258,66538,0,0,464,10266,0,0;QS=3,0;MQSB=0.017008;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,193:8:0 0,21,189:7:0 +17 300 . A 0 . DP=27;I16=11,15,0,0,1001,39455,0,0,1258,66538,0,0,469,10437,0,0;QS=3,0;MQSB=0.017008;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,204:8:0 0,21,210:7:0 +17 301 . G 0 . DP=25;I16=10,14,0,0,928,36116,0,0,1169,62097,0,0,476,10632,0,0;QS=3,0;MQSB=0.0310726;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,195:7:0 0,21,196:7:0 +17 302 . T 0 . DP=25;I16=10,14,0,0,879,32885,0,0,1169,62097,0,0,483,10849,0,0;QS=3,0;MQSB=0.0310726;MQ0F=0 PL:DP:DV 0,30,231:10:0 0,21,172:7:0 0,21,202:7:0 +17 302 . T TA 0 . INDEL;IDV=7;IMF=1;DP=25;I16=2,4,8,11,214,7674,793,33369,236,10564,993,55133,109,2229,377,8629;QS=0.511212,2.48879;VDB=0.27613;SGB=-4.22417;MQSB=0.0443614;MQ0F=0 PL:DP:DV 167,0,96:11:6 157,0,9:7:6 201,21,0:7:7 +17 303 . G 0 . DP=25;I16=10,15,0,0,976,38516,0,0,1229,65697,0,0,497,11181,0,0;QS=3,0;MQSB=0.0443614;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,197:7:0 0,21,195:7:0 +17 304 . C 0 . DP=27;I16=11,16,0,0,991,37005,0,0,1318,70138,0,0,503,11359,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,206:8:0 0,24,200:8:0 +17 305 . C 0 . DP=27;I16=11,16,0,0,1057,41761,0,0,1318,70138,0,0,510,11508,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,213:8:0 0,24,211:8:0 +17 306 . T 0 . DP=27;I16=11,16,0,0,1033,40253,0,0,1318,70138,0,0,517,11679,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,207:8:0 0,24,217:8:0 +17 307 . G 0 . DP=27;I16=11,15,0,0,984,37886,0,0,1289,69297,0,0,498,11198,0,0;QS=3,0;MQSB=0.174566;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,189:7:0 0,24,203:8:0 +17 308 . C 0 . DP=27;I16=11,16,0,0,892,30810,0,0,1318,70138,0,0,529,11991,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,178:8:0 0,24,185:8:0 +17 309 . G 0 . DP=27;I16=11,16,0,0,951,34599,0,0,1318,70138,0,0,535,12183,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:DV 0,33,243:11:0 0,24,183:8:0 0,24,205:8:0 +17 310 . A 0 . DP=27;I16=11,16,0,0,1001,38063,0,0,1318,70138,0,0,540,12350,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,200:8:0 0,24,217:8:0 +17 311 . C 0 . DP=27;I16=11,16,0,0,1037,40263,0,0,1318,70138,0,0,544,12492,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,215:8:0 0,24,210:8:0 +17 312 . A 0 . DP=26;I16=10,16,0,0,985,38043,0,0,1258,66538,0,0,549,12657,0,0;QS=3,0;MQSB=0.157183;MQ0F=0 PL:DP:DV 0,30,237:10:0 0,24,215:8:0 0,24,218:8:0 +17 313 . A 0 . DP=26;I16=10,16,0,0,983,37969,0,0,1258,66538,0,0,551,12695,0,0;QS=3,0;MQSB=0.157183;MQ0F=0 PL:DP:DV 0,30,235:10:0 0,24,219:8:0 0,24,215:8:0 +17 314 . A 0 . DP=27;I16=10,17,0,0,1050,41798,0,0,1318,70138,0,0,553,12757,0,0;QS=3,0;MQSB=0.195223;MQ0F=0 PL:DP:DV 0,33,250:11:0 0,24,217:8:0 0,24,227:8:0 +17 315 . G 0 . DP=26;I16=10,16,0,0,1025,40941,0,0,1289,69297,0,0,557,12843,0,0;QS=3,0;MQSB=0.252051;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,24,216:8:0 0,24,225:8:0 +17 316 . C 0 . DP=27;I16=10,15,0,0,983,39393,0,0,1252,67928,0,0,535,12277,0,0;QS=3,0;MQSB=0.312403;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,183:7:0 0,24,224:8:0 +17 317 . T 0 . DP=27;I16=10,16,0,0,1028,41392,0,0,1320,72056,0,0,547,12557,0,0;QS=3,0;MQSB=0.377061;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,230:8:0 0,24,206:8:0 +17 318 . G 0 . DP=27;I16=10,17,0,0,1038,40546,0,0,1349,72897,0,0,570,13018,0,0;QS=3,0;MQSB=0.297797;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,27,235:9:0 0,24,208:8:0 +17 319 . A 0 . DP=27;I16=9,17,0,0,994,38654,0,0,1289,69297,0,0,560,12906,0,0;QS=3,0;MQSB=0.346864;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,27,228:9:0 0,21,185:7:0 +17 320 . A 0 . DP=27;I16=10,17,0,0,1022,39418,0,0,1349,72897,0,0,573,13053,0,0;QS=3,0;MQSB=0.297797;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,27,230:9:0 0,24,211:8:0 +17 321 . T 0 . DP=27;I16=10,17,0,0,1026,39772,0,0,1349,72897,0,0,573,13029,0,0;QS=3,0;MQSB=0.297797;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,27,214:9:0 0,24,218:8:0 +17 322 . G 0 . DP=28;I16=10,18,0,0,1091,43151,0,0,1409,76497,0,0,573,13029,0,0;QS=3,0;MQSB=0.343265;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,27,226:9:0 0,27,223:9:0 +17 323 . C 0 . DP=28;I16=9,18,0,0,1067,42619,0,0,1349,72897,0,0,565,12939,0,0;QS=3,0;MQSB=0.394987;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,27,225:9:0 0,24,198:8:0 +17 324 . T 0 . DP=30;I16=12,18,0,0,1145,44221,0,0,1529,83697,0,0,573,13001,0,0;QS=3,0;MQSB=0.264959;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,27,237:9:0 0,33,255:11:0 +17 325 . A 0 . DP=31;I16=13,18,0,0,1132,42058,0,0,1589,87297,0,0,573,12925,0,0;QS=3,0;MQSB=0.235201;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,208:9:0 0,33,255:11:0 +17 326 . T 0 . DP=31;I16=13,18,0,0,1157,44193,0,0,1589,87297,0,0,574,12878,0,0;QS=3,0;MQSB=0.235201;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,216:9:0 0,33,255:11:0 +17 327 . C 0 . DP=31;I16=13,18,0,0,1147,43895,0,0,1589,87297,0,0,575,12861,0,0;QS=3,0;MQSB=0.235201;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,198:9:0 0,33,255:11:0 +17 328 . A 0 . DP=31;I16=13,18,0,0,1167,44531,0,0,1589,87297,0,0,574,12776,0,0;QS=3,0;MQSB=0.235201;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,226:9:0 0,33,255:11:0 +17 329 . T 0 . DP=31;I16=13,18,0,0,1210,47742,0,0,1589,87297,0,0,572,12676,0,0;QS=3,0;MQSB=0.235201;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,237:9:0 0,33,255:11:0 +17 330 . T 0 . DP=31;I16=13,18,0,0,1185,45839,0,0,1589,87297,0,0,568,12510,0,0;QS=3,0;MQSB=0.235201;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,27,231:9:0 0,33,255:11:0 +17 331 . T 0 . DP=32;I16=14,18,0,0,1154,42510,0,0,1649,90897,0,0,563,12327,0,0;QS=3,0;MQSB=0.210122;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,222:9:0 0,36,255:12:0 +17 332 . A 0 . DP=32;I16=14,18,0,0,1156,42666,0,0,1649,90897,0,0,560,12178,0,0;QS=3,0;MQSB=0.210122;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,214:9:0 0,33,255:11:0 +17 333 . A 0 . DP=32;I16=14,18,0,0,1141,41987,0,0,1649,90897,0,0,558,12064,0,0;QS=3,0;MQSB=0.210122;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,223:9:0 0,33,255:11:0 +17 334 . A 0 . DP=32;I16=14,18,0,0,1162,43328,0,0,1649,90897,0,0,556,11986,0,0;QS=3,0;MQSB=0.210122;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,221:9:0 0,33,255:11:0 +17 335 . A 0 . DP=32;I16=12,18,0,0,1077,40287,0,0,1529,83697,0,0,552,11934,0,0;QS=3,0;MQSB=0.264959;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,27,219:9:0 0,33,251:11:0 +17 336 . A 0 . DP=32;I16=14,17,0,0,1088,39758,0,0,1612,89528,0,0,536,11574,0,0;QS=3,0;MQSB=0.274662;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,211:8:0 0,36,255:12:0 +17 337 . C 0 . DP=32;I16=13,17,0,0,1115,42381,0,0,1552,85928,0,0,531,11565,0,0;QS=3,0;MQSB=0.301511;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,202:8:0 0,36,255:12:0 +17 338 . T 0 . DP=30;I16=14,16,0,0,1191,47979,0,0,1560,86456,0,0,554,11878,0,0;QS=3,0;MQSB=0.242376;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,226:8:0 0,36,255:12:0 +17 339 . C 0 . DP=31;I16=14,17,0,0,1130,43210,0,0,1589,87297,0,0,554,11874,0,0;QS=3,0;MQSB=0.175471;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,185:8:0 0,36,255:12:0 +17 340 . C 0 . DP=31;I16=14,17,0,0,1196,47044,0,0,1589,87297,0,0,554,11852,0,0;QS=3,0;MQSB=0.175471;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,221:8:0 0,36,255:12:0 +17 341 . T 0 . DP=31;I16=14,17,0,0,1227,48995,0,0,1589,87297,0,0,554,11862,0,0;QS=3,0;MQSB=0.175471;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,216:8:0 0,36,255:12:0 +17 342 . T 0 . DP=31;I16=14,17,0,0,1162,43942,0,0,1589,87297,0,0,554,11904,0,0;QS=3,0;MQSB=0.175471;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,210:8:0 0,36,255:12:0 +17 343 . G 0 . DP=32;I16=14,17,0,0,1150,43702,0,0,1620,90056,0,0,550,11962,0,0;QS=3,0;MQSB=0.283511;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,27,218:9:0 0,36,255:12:0 +17 344 . C 0 . DP=32;I16=14,18,0,0,1181,45169,0,0,1649,90897,0,0,554,12036,0,0;QS=3,0;MQSB=0.210122;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,217:9:0 0,36,255:12:0 +17 345 . T 0 . DP=31;I16=14,17,0,0,1205,47259,0,0,1589,87297,0,0,555,12129,0,0;QS=3,0;MQSB=0.175471;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,221:8:0 0,36,255:12:0 +17 346 . G 0 . DP=31;I16=15,16,0,0,1147,43597,0,0,1620,90056,0,0,557,12255,0,0;QS=3,0;MQSB=0.220358;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,212:8:0 0,36,255:12:0 +17 347 . G 0 . DP=31;I16=14,16,0,0,1119,42227,0,0,1560,86456,0,0,545,12189,0,0;QS=3,0;MQSB=0.242376;MQ0F=0 PL:DP:DV 0,30,251:10:0 0,24,207:8:0 0,36,255:12:0 +17 348 . T 0 . DP=32;I16=15,16,0,0,1145,43007,0,0,1620,90056,0,0,546,12300,0,0;QS=3,0;MQSB=0.220358;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,27,228:9:0 0,36,255:12:0 +17 349 . T 0 . DP=32;I16=16,16,0,0,1194,45350,0,0,1680,93656,0,0,565,12731,0,0;QS=3,0;MQSB=0.201402;MQ0F=0 PL:DP:DV 0,33,246:11:0 0,27,230:9:0 0,36,255:12:0 +17 350 . T 0 . DP=31;I16=16,15,0,0,1142,43072,0,0,1651,92815,0,0,567,12837,0,0;QS=3,0;MQSB=0.286505;MQ0F=0 PL:DP:DV 0,33,249:11:0 0,27,230:9:0 0,33,255:11:0 +17 351 . G 0 . DP=31;I16=16,15,0,0,1146,43750,0,0,1651,92815,0,0,568,12920,0,0;QS=3,0;MQSB=0.286505;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,212:9:0 0,33,255:11:0 +17 352 . A 0 . DP=31;I16=16,14,0,0,1150,45520,0,0,1591,89215,0,0,544,12404,0,0;QS=3,0;MQSB=0.242376;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,224:8:0 0,33,255:11:0 +17 353 . G 0 . DP=29;I16=15,14,0,0,1109,43095,0,0,1562,88374,0,0,570,13064,0,0;QS=3,0;MQSB=0.424373;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,27,231:9:0 0,30,255:10:0 +17 354 . A 0 . DP=28;I16=14,14,0,0,1078,42938,0,0,1502,84774,0,0,571,13075,0,0;QS=3,0;MQSB=0.450096;MQ0F=0 PL:DP:DV 0,27,225:9:0 0,27,244:9:0 0,30,255:10:0 +17 355 . G T, 0 . DP=28;I16=14,13,0,1,1001,37907,41,1681,1442,81174,60,3600,547,12487,25,625;QS=2.875,0.125,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.450096;BQB=1;MQ0F=0 PL:DP:DV 14,0,200,38,203,231:9:1 0,27,222,27,222,222:9:0 0,30,255,30,255,255:10:0 +17 356 . G 0 . DP=27;I16=14,13,0,0,993,37481,0,0,1465,83405,0,0,574,13174,0,0;QS=3,0;MQSB=0.580277;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,24,201:8:0 0,30,255:10:0 +17 357 . C 0 . DP=28;I16=14,13,0,0,1021,39471,0,0,1465,83405,0,0,550,12584,0,0;QS=3,0;MQSB=0.580277;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,205:8:0 0,27,251:9:0 +17 358 . A 0 . DP=28;I16=15,13,0,0,1050,40518,0,0,1525,87005,0,0,576,13216,0,0;QS=3,0;MQSB=0.556581;MQ0F=0 PL:DP:DV 0,30,254:10:0 0,24,197:8:0 0,30,255:10:0 +17 359 . G 0 . DP=29;I16=15,13,0,0,1085,42761,0,0,1525,87005,0,0,552,12620,0,0;QS=3,0;MQSB=0.556581;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,187:7:0 0,33,255:11:0 +17 360 . A 0 . DP=29;I16=15,14,0,0,1111,43259,0,0,1585,90605,0,0,579,13297,0,0;QS=3,0;MQSB=0.604224;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,24,220:8:0 0,33,255:11:0 +17 361 . A 0 . DP=29;I16=15,14,0,0,1116,43442,0,0,1585,90605,0,0,579,13273,0,0;QS=3,0;MQSB=0.604224;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,24,219:8:0 0,33,255:11:0 +17 362 . A 0 . DP=29;I16=16,13,0,0,1104,42700,0,0,1585,90605,0,0,580,13272,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,218:8:0 0,30,255:10:0 +17 363 . A 0 . DP=29;I16=16,13,0,0,1087,41437,0,0,1585,90605,0,0,581,13245,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,213:8:0 0,30,255:10:0 +17 364 . T 0 . DP=29;I16=16,13,0,0,1032,37960,0,0,1585,90605,0,0,582,13244,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:DV 0,33,250:11:0 0,24,205:8:0 0,30,255:10:0 +17 365 . G 0 . DP=29;I16=16,13,0,0,1105,43079,0,0,1585,90605,0,0,582,13218,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,211:8:0 0,30,255:10:0 +17 366 . A 0 . DP=29;I16=16,13,0,0,1090,41562,0,0,1585,90605,0,0,581,13167,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,211:8:0 0,30,255:10:0 +17 367 . T 0 . DP=29;I16=16,13,0,0,1055,39149,0,0,1585,90605,0,0,579,13093,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,204:8:0 0,30,255:10:0 +17 368 . A 0 . DP=29;I16=16,13,0,0,1054,39632,0,0,1585,90605,0,0,576,12998,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,208:8:0 0,30,255:10:0 +17 369 . T 0 . DP=28;I16=16,11,0,0,1037,40275,0,0,1496,86164,0,0,548,12256,0,0;QS=3,0;MQSB=0.659218;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,21,196:7:0 0,30,255:10:0 +17 370 . C 0 . DP=28;I16=16,12,0,0,1045,40219,0,0,1556,89764,0,0,570,12790,0,0;QS=3,0;MQSB=0.705296;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,201:8:0 0,30,255:10:0 +17 371 . T 0 . DP=29;I16=16,13,0,0,1155,46591,0,0,1616,93364,0,0,567,12725,0,0;QS=3,0;MQSB=0.744925;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,227:8:0 0,33,255:11:0 +17 372 . C 0 . DP=30;I16=16,14,0,0,1139,44019,0,0,1676,96964,0,0,564,12636,0,0;QS=3,0;MQSB=0.779025;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,215:8:0 0,33,255:11:0 +17 373 . A 0 . DP=30;I16=16,14,0,0,1142,44118,0,0,1676,96964,0,0,561,12525,0,0;QS=3,0;MQSB=0.779025;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,220:8:0 0,33,255:11:0 +17 374 . T 0 . DP=30;I16=16,14,0,0,1098,41180,0,0,1676,96964,0,0,556,12344,0,0;QS=3,0;MQSB=0.779025;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,221:8:0 0,33,255:11:0 +17 375 . A T, 0 . DP=31;I16=17,13,0,1,1138,43798,14,196,1676,96964,60,3600,547,12177,4,16;QS=2.9661,0.0338983,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.763662;BQB=1;MQ0F=0 PL:DP:DV 0,36,255,36,255,255:12:0 0,24,218,24,218,218:8:0 0,18,255,30,255,255:11:1 +17 376 . G 0 . DP=31;I16=17,14,0,0,1131,42581,0,0,1736,100564,0,0,547,12073,0,0;QS=3,0;MQSB=0.763662;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,220:8:0 0,33,255:11:0 +17 377 . T 0 . DP=31;I16=16,14,0,0,1105,41629,0,0,1676,96964,0,0,518,11360,0,0;QS=3,0;MQSB=0.779025;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,211:8:0 0,33,255:11:0 +17 378 . T 0 . DP=30;I16=18,12,0,0,1098,41066,0,0,1707,99723,0,0,541,11927,0,0;QS=3,0;MQSB=0.878946;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,186:7:0 0,30,255:10:0 +17 379 . G 0 . DP=29;I16=18,10,0,0,1053,40181,0,0,1618,95282,0,0,534,11848,0,0;QS=3,0;MQSB=0.981777;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,187:7:0 0,30,255:10:0 +17 380 . C 0 . DP=29;I16=18,10,0,0,1087,42743,0,0,1618,95282,0,0,514,11172,0,0;QS=3,0;MQSB=0.981777;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,177:6:0 0,30,255:10:0 +17 381 . T 0 . DP=29;I16=18,11,0,0,1168,47412,0,0,1678,98882,0,0,537,11729,0,0;QS=3,0;MQSB=0.987702;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,212:7:0 0,30,255:10:0 +17 382 . T 0 . DP=29;I16=17,11,0,0,1054,40450,0,0,1618,95282,0,0,510,11068,0,0;QS=3,0;MQSB=0.990092;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,182:7:0 0,30,255:10:0 +17 383 . T 0 . DP=29;I16=18,10,0,0,1052,39798,0,0,1618,95282,0,0,507,11013,0,0;QS=3,0;MQSB=0.981777;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,165:6:0 0,30,255:10:0 +17 384 . A 0 . DP=31;I16=19,11,0,0,1077,39885,0,0,1738,102482,0,0,504,10988,0,0;QS=3,0;MQSB=0.985292;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,176:7:0 0,30,255:10:0 +17 385 . C 0 . DP=31;I16=19,12,0,0,1118,41180,0,0,1798,106082,0,0,527,11569,0,0;QS=3,0;MQSB=0.989977;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,186:8:0 0,30,255:10:0 +17 386 . T 0 . DP=30;I16=18,12,0,0,1158,45592,0,0,1738,102482,0,0,526,11556,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,191:7:0 0,30,255:10:0 +17 387 . T 0 . DP=30;I16=18,12,0,0,1105,41821,0,0,1738,102482,0,0,525,11573,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,187:7:0 0,30,255:10:0 +17 388 . T 0 . DP=29;I16=17,12,0,0,1089,41577,0,0,1678,98882,0,0,523,11519,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,180:6:0 0,30,255:10:0 +17 389 . G 0 . DP=29;I16=17,12,0,0,1067,40095,0,0,1678,98882,0,0,520,11444,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,171:6:0 0,30,255:10:0 +17 390 . C 0 . DP=29;I16=17,12,0,0,1071,40423,0,0,1678,98882,0,0,517,11399,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,162:6:0 0,30,255:10:0 +17 391 . A 0 . DP=29;I16=18,11,0,0,1091,41603,0,0,1647,96123,0,0,515,11383,0,0;QS=3,0;MQSB=0.995968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,163:6:0 0,30,255:10:0 +17 392 . T 0 . DP=29;I16=18,11,0,0,1046,38838,0,0,1647,96123,0,0,515,11395,0,0;QS=3,0;MQSB=0.995968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,153:5:0 0,33,255:11:0 +17 393 . A 0 . DP=28;I16=17,11,0,0,1014,37582,0,0,1587,92523,0,0,517,11435,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,133:5:0 0,33,255:11:0 +17 394 . T 0 . DP=28;I16=17,11,0,0,1022,38342,0,0,1587,92523,0,0,519,11503,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,141:5:0 0,33,255:11:0 +17 395 . T 0 . DP=28;I16=17,11,0,0,1060,40596,0,0,1587,92523,0,0,521,11599,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,164:5:0 0,33,255:11:0 +17 396 . T 0 . DP=28;I16=17,11,0,0,1032,39228,0,0,1587,92523,0,0,523,11723,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,158:5:0 0,33,255:11:0 +17 397 . T 0 . DP=28;I16=17,11,0,0,1046,39510,0,0,1587,92523,0,0,524,11824,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,149:5:0 0,33,255:11:0 +17 398 . A 0 . DP=28;I16=17,11,0,0,1021,38105,0,0,1587,92523,0,0,524,11850,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,144:5:0 0,30,255:10:0 +17 399 . A 0 . DP=28;I16=17,11,0,0,1015,38469,0,0,1587,92523,0,0,526,11900,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,140:5:0 0,30,255:10:0 +17 400 . A 0 . DP=29;I16=17,12,0,0,1056,39702,0,0,1647,96123,0,0,526,11828,0,0;QS=3,0;MQSB=0.988062;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,159:5:0 0,33,255:11:0 +17 401 . A 0 . DP=29;I16=17,11,0,0,1052,40302,0,0,1587,92523,0,0,501,11113,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,160:5:0 0,30,255:10:0 +17 402 . T 0 . DP=29;I16=17,12,0,0,1082,41232,0,0,1647,96123,0,0,526,11680,0,0;QS=3,0;MQSB=0.988062;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,149:5:0 0,33,255:11:0 +17 403 . T 0 . DP=29;I16=17,12,0,0,1085,40985,0,0,1647,96123,0,0,526,11654,0,0;QS=3,0;MQSB=0.988062;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,148:5:0 0,33,255:11:0 +17 404 . G 0 . DP=29;I16=17,12,0,0,1074,40524,0,0,1647,96123,0,0,525,11609,0,0;QS=3,0;MQSB=0.988062;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,131:5:0 0,33,255:11:0 +17 405 . T 0 . DP=27;I16=16,10,0,0,988,37870,0,0,1498,88082,0,0,519,11543,0,0;QS=3,0;MQSB=0.987578;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,103:3:0 0,30,255:10:0 +17 406 . G 0 . DP=27;I16=16,11,0,0,976,36752,0,0,1558,91682,0,0,527,11601,0,0;QS=3,0;MQSB=0.992419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,125:4:0 0,30,247:10:0 +17 407 . A 0 . DP=27;I16=16,11,0,0,1007,38355,0,0,1558,91682,0,0,526,11538,0,0;QS=3,0;MQSB=0.992419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,125:4:0 0,30,255:10:0 +17 408 . C 0 . DP=28;I16=16,11,0,0,1006,38136,0,0,1558,91682,0,0,521,11489,0,0;QS=3,0;MQSB=0.992419;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,110:3:0 0,30,244:10:0 +17 409 . T 0 . DP=29;I16=17,12,0,0,1100,42734,0,0,1678,98882,0,0,525,11503,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,131:4:0 0,33,255:11:0 +17 410 . T 0 . DP=29;I16=17,12,0,0,1035,38325,0,0,1678,98882,0,0,524,11432,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,125:4:0 0,33,255:11:0 +17 411 . T 0 . DP=29;I16=17,10,0,0,1003,37747,0,0,1558,91682,0,0,496,10716,0,0;QS=3,0;MQSB=0.984677;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,104:3:0 0,30,255:10:0 +17 412 . C T, 0 . DP=30;I16=17,12,1,0,1094,42458,14,196,1678,98882,60,3600,495,10659,25,625;QS=2.97455,0.0254545,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.991968;BQB=1;MQ0F=0 PL:DP:DV 0,30,255,42,255,255:15:1 0,12,124,12,124,124:4:0 0,33,255,33,255,255:11:0 +17 413 . A 0 . DP=31;I16=18,13,0,0,1189,45985,0,0,1798,106082,0,0,520,11258,0,0;QS=3,0;MQSB=0.995005;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,102:3:0 0,33,255:11:0 +17 414 . T 0 . DP=30;I16=18,12,0,0,1151,44355,0,0,1738,102482,0,0,523,11265,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,109:3:0 0,33,255:11:0 +17 415 . G 0 . DP=30;I16=18,12,0,0,1131,43175,0,0,1738,102482,0,0,526,11306,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,110:3:0 0,33,255:11:0 +17 416 . G 0 . DP=30;I16=17,12,0,0,1083,41273,0,0,1678,98882,0,0,514,11156,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,114:3:0 0,30,253:10:0 +17 417 . C 0 . DP=30;I16=18,12,0,0,1114,42244,0,0,1738,102482,0,0,531,11439,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,108:3:0 0,33,255:11:0 +17 418 . A 0 . DP=30;I16=18,12,0,0,1146,44248,0,0,1738,102482,0,0,532,11478,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,111:3:0 0,33,255:11:0 +17 419 . T 0 . DP=30;I16=18,12,0,0,1117,42327,0,0,1738,102482,0,0,532,11498,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,112:3:0 0,33,255:11:0 +17 420 . A 0 . DP=31;I16=18,13,0,0,1117,41011,0,0,1798,106082,0,0,532,11550,0,0;QS=3,0;MQSB=0.995005;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,108:3:0 0,36,255:12:0 +17 421 . A 0 . DP=33;I16=19,14,0,0,1208,45398,0,0,1887,110523,0,0,533,11635,0,0;QS=3,0;MQSB=0.986656;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,113:3:0 0,42,255:14:0 +17 422 . A 0 . DP=33;I16=19,13,0,0,1205,46441,0,0,1827,106923,0,0,510,11082,0,0;QS=3,0;MQSB=0.991023;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,116:3:0 0,39,255:13:0 +17 423 . T 0 . DP=32;I16=19,13,0,0,1202,45416,0,0,1827,106923,0,0,538,11818,0,0;QS=3,0;MQSB=0.991023;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,110:3:0 0,39,255:13:0 +17 424 . A 0 . DP=32;I16=19,13,0,0,1147,41685,0,0,1827,106923,0,0,539,11867,0,0;QS=3,0;MQSB=0.991023;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,106:3:0 0,39,255:13:0 +17 425 . A 0 . DP=29;I16=16,13,0,0,1070,40616,0,0,1647,96123,0,0,542,11900,0,0;QS=3,0;MQSB=0.976248;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,111:3:0 0,33,249:11:0 +17 426 . T 0 . DP=29;I16=16,12,0,0,997,36561,0,0,1587,92523,0,0,519,11287,0,0;QS=3,0;MQSB=0.982906;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,105:3:0 0,30,225:10:0 +17 427 . A 0 . DP=29;I16=16,13,0,0,1024,37266,0,0,1647,96123,0,0,546,11952,0,0;QS=3,0;MQSB=0.976248;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,111:3:0 0,33,242:11:0 +17 428 . C 0 . DP=29;I16=16,13,0,0,1064,39706,0,0,1647,96123,0,0,548,12020,0,0;QS=3,0;MQSB=0.976248;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,111:3:0 0,33,254:11:0 +17 429 . T 0 . DP=30;I16=16,14,0,0,1150,44918,0,0,1707,99723,0,0,549,12067,0,0;QS=3,0;MQSB=0.969373;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,115:3:0 0,33,255:11:0 +17 430 . G 0 . DP=30;I16=16,14,0,0,1113,42443,0,0,1707,99723,0,0,551,12145,0,0;QS=3,0;MQSB=0.969373;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,112:3:0 0,33,246:11:0 +17 431 . G 0 . DP=30;I16=14,14,0,0,1003,36953,0,0,1587,92523,0,0,553,12255,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,101:3:0 0,30,225:10:0 +17 432 . T 0 . DP=28;I16=14,14,0,0,1049,39621,0,0,1587,92523,0,0,556,12346,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,114:3:0 0,30,255:10:0 +17 433 . T 0 . DP=28;I16=14,12,0,0,949,35443,0,0,1467,85323,0,0,509,11217,0,0;QS=3,0;MQSB=0.967472;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,112:3:0 0,27,227:9:0 +17 434 . T 0 . DP=29;I16=15,14,0,0,1036,37654,0,0,1647,96123,0,0,561,12567,0,0;QS=3,0;MQSB=0.960561;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,98:3:0 0,30,243:10:0 +17 435 . A 0 . DP=29;I16=15,13,0,0,1024,37970,0,0,1587,92523,0,0,556,12560,0,0;QS=3,0;MQSB=0.968414;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,103:3:0 0,30,237:10:0 +17 436 . T 0 . DP=28;I16=14,14,0,0,998,36220,0,0,1587,92523,0,0,564,12654,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,110:3:0 0,27,223:9:0 +17 437 . T 0 . DP=28;I16=13,14,0,0,990,36832,0,0,1558,91682,0,0,549,12435,0,0;QS=3,0;MQSB=0.999706;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,109:3:0 0,24,207:8:0 +17 438 . A 0 . DP=28;I16=14,13,0,0,972,35640,0,0,1527,88923,0,0,540,12082,0,0;QS=3,0;MQSB=0.9585;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,107:3:0 0,24,216:8:0 +17 439 . C 0 . DP=28;I16=14,14,0,0,1055,40273,0,0,1587,92523,0,0,563,12649,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,107:3:0 0,27,224:9:0 +17 440 . A 0 . DP=28;I16=14,14,0,0,1095,43251,0,0,1587,92523,0,0,561,12615,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,115:3:0 0,27,247:9:0 +17 441 . G 0 . DP=29;I16=15,14,0,0,1068,40344,0,0,1647,96123,0,0,559,12605,0,0;QS=3,0;MQSB=0.960561;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,104:3:0 0,27,198:9:0 +17 442 . A 0 . DP=29;I16=15,14,0,0,1091,41507,0,0,1647,96123,0,0,558,12620,0,0;QS=3,0;MQSB=0.960561;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,112:3:0 0,27,233:9:0 +17 443 . A 0 . DP=30;I16=15,14,0,0,1173,49439,0,0,1647,96123,0,0,557,12661,0,0;QS=3,0;MQSB=0.960561;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,129:3:0 0,27,246:9:0 +17 444 . G 0 . DP=29;I16=15,13,0,0,1095,44661,0,0,1587,92523,0,0,557,12727,0,0;QS=3,0;MQSB=0.968414;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,91:2:0 0,27,227:9:0 +17 445 . C 0 . DP=30;I16=16,13,0,0,1100,43706,0,0,1647,96123,0,0,557,12817,0,0;QS=3,0;MQSB=0.976248;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,111:3:0 0,27,219:9:0 +17 446 . A 0 . DP=30;I16=16,13,0,0,1107,44265,0,0,1647,96123,0,0,557,12881,0,0;QS=3,0;MQSB=0.976248;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,115:3:0 0,27,232:9:0 +17 447 . C 0 . DP=29;I16=16,12,0,0,1108,45364,0,0,1618,95282,0,0,555,12817,0,0;QS=3,0;MQSB=0.856268;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,114:3:0 0,27,235:9:0 +17 448 . T 0 . DP=29;I16=16,12,0,0,1125,47237,0,0,1618,95282,0,0,553,12773,0,0;QS=3,0;MQSB=0.856268;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,118:3:0 0,27,240:9:0 +17 449 . A 0 . DP=28;I16=15,12,0,0,1091,45981,0,0,1558,91682,0,0,552,12748,0,0;QS=3,0;MQSB=0.84246;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,90:2:0 0,27,245:9:0 +17 450 . G 0 . DP=28;I16=15,12,0,0,1069,44603,0,0,1558,91682,0,0,551,12741,0,0;QS=3,0;MQSB=0.84246;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,91:2:0 0,27,233:9:0 +17 451 . A 0 . DP=28;I16=15,12,0,0,1021,41371,0,0,1558,91682,0,0,550,12752,0,0;QS=3,0;MQSB=0.84246;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,93:2:0 0,27,244:9:0 +17 452 . A 0 . DP=31;I16=18,11,0,0,1079,43353,0,0,1678,98882,0,0,530,12420,0,0;QS=3,0;MQSB=0.884952;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,110:3:0 0,24,225:8:0 +17 453 . A 0 . DP=31;I16=17,11,0,0,1037,41069,0,0,1649,98041,0,0,508,11882,0,0;QS=3,0;MQSB=0.967085;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,111:3:0 0,21,221:7:0 +17 454 . A 0 . DP=31;I16=18,12,0,0,1158,47028,0,0,1738,102482,0,0,554,12904,0,0;QS=3,0;MQSB=0.878946;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,113:3:0 0,30,255:10:0 +17 455 . T 0 . DP=32;I16=17,13,0,0,1148,46574,0,0,1715,100251,0,0,550,12864,0,0;QS=3,0;MQSB=0.973855;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,113:3:0 0,33,255:11:0 +17 456 . G 0 . DP=32;I16=17,13,0,0,1161,47287,0,0,1746,103010,0,0,534,12296,0,0;QS=3,0;MQSB=0.998031;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,116:3:0 0,30,245:10:0 +17 457 . C 0 . DP=33;I16=19,13,0,0,1218,48642,0,0,1835,107451,0,0,563,12967,0,0;QS=3,0;MQSB=0.985204;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,118:3:0 0,33,255:11:0 +17 458 . A 0 . DP=33;I16=19,13,0,0,1226,49034,0,0,1835,107451,0,0,568,12990,0,0;QS=3,0;MQSB=0.985204;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,111:3:0 0,33,255:11:0 +17 459 . T 0 . DP=33;I16=18,13,0,0,1167,46981,0,0,1775,103851,0,0,565,12945,0,0;QS=3,0;MQSB=0.980167;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,92:2:0 0,33,255:11:0 +17 460 . G 0 . DP=32;I16=19,12,0,0,1219,50105,0,0,1775,103851,0,0,575,12929,0,0;QS=3,0;MQSB=0.989977;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,116:3:0 0,30,255:10:0 +17 461 . T 0 . DP=32;I16=19,12,0,0,1213,49819,0,0,1775,103851,0,0,577,12845,0,0;QS=3,0;MQSB=0.989977;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,115:3:0 0,30,255:10:0 +17 462 . G 0 . DP=32;I16=19,12,0,0,1190,48962,0,0,1775,103851,0,0,580,12792,0,0;QS=3,0;MQSB=0.989977;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,119:4:0 0,30,241:10:0 +17 463 . G 0 . DP=32;I16=19,12,0,0,1114,44214,0,0,1775,103851,0,0,584,12770,0,0;QS=3,0;MQSB=0.989977;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,114:4:0 0,30,221:10:0 +17 464 . A 0 . DP=32;I16=18,11,0,0,1100,43908,0,0,1686,99410,0,0,556,12106,0,0;QS=3,0;MQSB=0.99095;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,133:4:0 0,24,213:8:0 +17 465 . C 0 . DP=33;I16=20,11,0,0,1191,48085,0,0,1775,103851,0,0,586,12786,0,0;QS=3,0;MQSB=0.996597;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,140:5:0 0,27,231:9:0 +17 466 . A 0 . DP=34;I16=21,12,0,0,1293,53311,0,0,1895,111051,0,0,597,12897,0,0;QS=3,0;MQSB=0.995633;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,154:5:0 0,30,255:10:0 +17 467 . A 0 . DP=34;I16=21,11,0,0,1256,51450,0,0,1835,107451,0,0,597,12891,0,0;QS=3,0;MQSB=0.998231;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,157:5:0 0,27,248:9:0 +17 468 . A 0 . DP=35;I16=22,12,0,0,1274,51268,0,0,1955,114651,0,0,604,12904,0,0;QS=3,0;MQSB=0.997406;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,154:5:0 0,30,251:10:0 +17 469 . A 0 . DP=35;I16=22,12,0,0,1285,52989,0,0,1955,114651,0,0,608,12940,0,0;QS=3,0;MQSB=0.997406;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,146:5:0 0,30,255:10:0 +17 470 . G 0 . DP=35;I16=22,12,0,0,1281,51055,0,0,1955,114651,0,0,612,13016,0,0;QS=3,0;MQSB=0.997406;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,148:5:0 0,30,238:10:0 +17 471 . T 0 . DP=36;I16=22,11,0,0,1239,49021,0,0,1918,113282,0,0,599,12825,0,0;QS=3,0;MQSB=0.915545;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,150:5:0 0,27,232:9:0 +17 472 . T 0 . DP=35;I16=21,12,0,0,1245,48915,0,0,1926,113810,0,0,595,12559,0,0;QS=3,0;MQSB=0.988858;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,153:5:0 0,27,237:9:0 +17 473 . G 0 . DP=35;I16=21,12,0,0,1307,53473,0,0,1926,113810,0,0,599,12651,0,0;QS=3,0;MQSB=0.988858;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,141:5:0 0,27,249:9:0 +17 474 . G 0 . DP=36;I16=22,12,0,0,1284,51708,0,0,1986,117410,0,0,602,12734,0,0;QS=3,0;MQSB=0.986937;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,131:5:0 0,30,255:10:0 +17 475 . G 0 . DP=36;I16=23,12,0,0,1311,51609,0,0,2015,118251,0,0,631,13485,0,0;QS=3,0;MQSB=0.998642;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,141:5:0 0,33,252:11:0 +17 476 . A 0 . DP=36;I16=23,12,0,0,1312,52078,0,0,2015,118251,0,0,634,13606,0,0;QS=3,0;MQSB=0.998642;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,157:5:0 0,33,255:11:0 +17 477 . T 0 . DP=36;I16=23,12,0,0,1318,52668,0,0,2015,118251,0,0,637,13773,0,0;QS=3,0;MQSB=0.998642;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,148:5:0 0,33,255:11:0 +17 478 . T 0 . DP=38;I16=25,12,0,0,1338,51774,0,0,2135,125451,0,0,637,13833,0,0;QS=3,0;MQSB=0.999868;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,18,154:6:0 0,33,255:11:0 +17 479 . A 0 . DP=38;I16=25,12,0,0,1420,57788,0,0,2135,125451,0,0,639,13935,0,0;QS=3,0;MQSB=0.999868;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,18,163:6:0 0,33,255:11:0 +17 480 . G 0 . DP=37;I16=25,11,0,0,1438,60172,0,0,2075,121851,0,0,641,14029,0,0;QS=3,0;MQSB=0.999853;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,165:6:0 0,33,255:11:0 +17 481 . G 0 . DP=37;I16=25,11,0,0,1392,55824,0,0,2075,121851,0,0,642,14112,0,0;QS=3,0;MQSB=0.999853;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,165:6:0 0,33,255:11:0 +17 482 . A 0 . DP=37;I16=24,11,0,0,1352,55134,0,0,2015,118251,0,0,618,13608,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,143:5:0 0,33,255:11:0 +17 483 . G 0 . DP=37;I16=24,12,0,0,1417,57747,0,0,2075,121851,0,0,642,14240,0,0;QS=3,0;MQSB=0.999437;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,165:6:0 0,33,255:11:0 +17 484 . A 0 . DP=36;I16=24,11,0,0,1340,53992,0,0,2015,118251,0,0,643,14281,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,168:6:0 0,33,255:11:0 +17 485 . G 0 . DP=35;I16=23,12,0,0,1329,51411,0,0,2015,118251,0,0,669,14931,0,0;QS=3,0;MQSB=0.998642;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,160:6:0 0,33,255:11:0 +17 486 . A 0 . DP=34;I16=22,12,0,0,1311,51523,0,0,1955,114651,0,0,671,14989,0,0;QS=3,0;MQSB=0.997406;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,173:6:0 0,33,255:11:0 +17 487 . G 0 . DP=34;I16=22,12,0,0,1306,50760,0,0,1955,114651,0,0,672,15030,0,0;QS=3,0;MQSB=0.997406;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,169:6:0 0,33,255:11:0 +17 488 . A 0 . DP=35;I16=22,12,0,0,1274,48140,0,0,1986,117410,0,0,646,14380,0,0;QS=3,0;MQSB=0.986937;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,177:6:0 0,30,255:10:0 +17 489 . A 0 . DP=35;I16=23,12,0,0,1264,46916,0,0,2015,118251,0,0,671,15015,0,0;QS=3,0;MQSB=0.998642;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,175:6:0 0,33,255:11:0 +17 490 . A 0 . DP=36;I16=24,12,0,0,1332,50280,0,0,2075,121851,0,0,671,15061,0,0;QS=3,0;MQSB=0.999437;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,188:7:0 0,33,255:11:0 +17 491 . T 0 . DP=36;I16=24,12,0,0,1284,46802,0,0,2075,121851,0,0,671,15093,0,0;QS=3,0;MQSB=0.999437;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,178:7:0 0,33,255:11:0 +17 492 . G 0 . DP=35;I16=21,12,0,0,1252,48326,0,0,1926,113810,0,0,621,13859,0,0;QS=3,0;MQSB=0.988858;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,172:6:0 0,30,251:10:0 +17 493 . A 0 . DP=34;I16=22,11,0,0,1273,49481,0,0,1926,113810,0,0,650,14672,0,0;QS=3,0;MQSB=0.981935;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,186:7:0 0,24,240:8:0 +17 494 . A 0 . DP=34;I16=22,12,0,0,1326,52604,0,0,1986,117410,0,0,672,15182,0,0;QS=3,0;MQSB=0.986937;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,196:7:0 0,27,255:9:0 +17 495 . G 0 . DP=34;I16=21,12,0,0,1255,48577,0,0,1926,113810,0,0,647,14611,0,0;QS=3,0;MQSB=0.988858;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,168:6:0 0,27,244:9:0 +17 496 . A 0 . DP=34;I16=22,12,0,0,1250,46926,0,0,1986,117410,0,0,670,15220,0,0;QS=3,0;MQSB=0.986937;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,186:7:0 0,27,249:9:0 +17 497 . C 0 . DP=34;I16=22,12,0,0,1250,47006,0,0,1986,117410,0,0,665,15087,0,0;QS=3,0;MQSB=0.986937;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,164:7:0 0,27,239:9:0 +17 498 . A 0 . DP=34;I16=22,12,0,0,1286,49158,0,0,1986,117410,0,0,661,14987,0,0;QS=3,0;MQSB=0.986937;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,185:7:0 0,27,252:9:0 +17 499 . T 0 . DP=34;I16=23,11,0,0,1224,45284,0,0,1986,117410,0,0,659,14919,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,183:7:0 0,30,255:10:0 +17 500 . A 0 . DP=34;I16=23,11,0,0,1230,45152,0,0,1986,117410,0,0,657,14833,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,179:7:0 0,30,255:10:0 +17 501 . T 0 . DP=33;I16=23,10,0,0,1241,47167,0,0,1926,113810,0,0,656,14778,0,0;QS=3,0;MQSB=0.972757;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,186:7:0 0,27,241:9:0 +17 502 . G 0 . DP=33;I16=23,10,0,0,1215,45829,0,0,1926,113810,0,0,655,14753,0,0;QS=3,0;MQSB=0.972757;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,183:7:0 0,27,235:9:0 +17 503 . T 0 . DP=34;I16=23,11,0,0,1194,43366,0,0,1986,117410,0,0,654,14758,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,177:7:0 0,27,234:9:0 +17 504 . C 0 . DP=34;I16=23,11,0,0,1218,45552,0,0,1986,117410,0,0,651,14643,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,183:7:0 0,27,219:9:0 +17 505 . C 0 . DP=35;I16=23,11,0,0,1207,44321,0,0,1986,117410,0,0,641,14509,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,189:7:0 0,27,221:9:0 +17 506 . A 0 . DP=35;I16=24,11,0,0,1266,46776,0,0,2046,121010,0,0,646,14504,0,0;QS=3,0;MQSB=0.977529;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,188:7:0 0,27,231:9:0 +17 507 . C 0 . DP=35;I16=23,11,0,0,1220,45016,0,0,1986,117410,0,0,635,14401,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,183:7:0 0,27,226:9:0 +17 508 . A 0 . DP=34;I16=24,10,0,0,1204,44542,0,0,1986,117410,0,0,643,14491,0,0;QS=3,0;MQSB=0.970272;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,189:7:0 0,27,220:9:0 +17 509 . C 0 . DP=34;I16=24,10,0,0,1272,48272,0,0,1986,117410,0,0,640,14430,0,0;QS=3,0;MQSB=0.970272;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,186:7:0 0,27,241:9:0 +17 510 . A 0 . DP=34;I16=22,11,0,0,1194,44196,0,0,1926,113810,0,0,613,13773,0,0;QS=3,0;MQSB=0.981935;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,187:7:0 0,24,221:8:0 +17 511 . A 0 . DP=34;I16=23,11,0,0,1222,45562,0,0,1986,117410,0,0,637,14395,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,195:7:0 0,24,233:8:0 +17 512 . A C, 0 . DP=33;I16=22,10,0,1,1121,40793,13,169,1866,110210,60,3600,628,14340,9,81;QS=2.97719,0.022807,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.981935;BQB=1;MQ0F=0 PL:DP:DV 0,39,255,51,255,255:18:1 0,21,183,21,183,183:7:0 0,24,231,24,231,231:8:0 +17 513 . A 0 . DP=32;I16=20,10,0,0,1115,42183,0,0,1746,103010,0,0,598,13624,0,0;QS=3,0;MQSB=0.980594;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,175:6:0 0,24,233:8:0 +17 514 . A T, 0 . DP=32;I16=20,9,0,1,1066,40004,16,256,1686,99410,60,3600,586,13500,11,121;QS=2.97075,0.0292505,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.980594;BQB=1;MQ0F=0 PL:DP:DV 0,31,255,45,255,255:16:1 0,18,171,18,171,171:6:0 0,24,235,24,235,235:8:0 +17 515 . C 0 . DP=32;I16=18,10,0,0,1010,37294,0,0,1626,95810,0,0,561,12915,0,0;QS=3,0;MQSB=0.986018;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,167:6:0 0,24,211:8:0 +17 516 . C 0 . DP=32;I16=21,10,0,0,1100,40570,0,0,1806,106610,0,0,612,13954,0,0;QS=3,0;MQSB=0.977926;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,187:7:0 0,24,215:8:0 +17 517 . T 0 . DP=33;I16=23,10,0,0,1269,49995,0,0,1926,113810,0,0,636,14626,0,0;QS=3,0;MQSB=0.972757;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,201:7:0 0,24,242:8:0 +17 518 . G 0 . DP=34;I16=24,10,0,0,1247,46839,0,0,1986,117410,0,0,636,14696,0,0;QS=3,0;MQSB=0.970272;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,182:7:0 0,24,220:8:0 +17 519 . T 0 . DP=36;I16=25,11,0,0,1283,46693,0,0,2106,124610,0,0,636,14742,0,0;QS=3,0;MQSB=0.975394;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,21,177:7:0 0,24,224:8:0 +17 520 . T 0 . DP=36;I16=24,11,0,0,1238,44894,0,0,2046,121010,0,0,613,14193,0,0;QS=3,0;MQSB=0.977529;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,180:7:0 0,24,223:8:0 +17 521 . C 0 . DP=34;I16=25,9,0,0,1280,49454,0,0,1986,117410,0,0,641,14875,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,191:7:0 0,21,204:7:0 +17 522 . A 0 . DP=32;I16=24,8,0,0,1158,43228,0,0,1897,112969,0,0,646,14960,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,185:7:0 0,15,170:5:0 +17 523 . T G, 0 . DP=32;I16=23,8,1,0,1184,45708,15,225,1837,109369,60,3600,626,14446,25,625;QS=2.9794,0.0206044,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.872525;BQB=1;MQ0F=0 PL:DP:DV 0,44,255,57,255,255:20:1 0,21,191,21,191,191:7:0 0,15,166,15,166,166:5:0 +17 524 . T 0 . DP=32;I16=24,7,0,0,1084,39474,0,0,1837,109369,0,0,629,14483,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,194:7:0 0,12,140:4:0 +17 525 . G 0 . DP=32;I16=24,7,0,0,1181,45669,0,0,1837,109369,0,0,631,14495,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,188:7:0 0,12,129:4:0 +17 526 . C 0 . DP=32;I16=24,7,0,0,1146,43950,0,0,1860,111600,0,0,633,14531,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,185:7:0 0,12,131:4:0 +17 527 . A 0 . DP=33;I16=24,8,0,0,1209,46265,0,0,1897,112969,0,0,636,14634,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,194:7:0 0,18,181:6:0 +17 528 . G 0 . DP=33;I16=24,8,0,0,1256,49824,0,0,1897,112969,0,0,634,14484,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,18,169:6:0 0,18,193:6:0 +17 529 . C 0 . DP=32;I16=24,7,0,0,1148,44362,0,0,1837,109369,0,0,633,14357,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,187:7:0 0,18,184:6:0 +17 530 . T 0 . DP=32;I16=25,7,0,0,1244,49168,0,0,1897,112969,0,0,657,14883,0,0;QS=3,0;MQSB=0.850154;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,196:7:0 0,18,202:6:0 +17 531 . T 0 . DP=32;I16=25,7,0,0,1177,44171,0,0,1897,112969,0,0,654,14714,0,0;QS=3,0;MQSB=0.850154;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,181:7:0 0,18,193:6:0 +17 532 . T 0 . DP=32;I16=24,7,0,0,1153,43543,0,0,1837,109369,0,0,630,14116,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,181:7:0 0,18,192:6:0 +17 533 . C 0 . DP=32;I16=24,7,0,0,1142,43940,0,0,1837,109369,0,0,619,13649,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,178:7:0 0,18,180:6:0 +17 534 . T 0 . DP=31;I16=24,6,0,0,1212,49426,0,0,1777,105769,0,0,615,13479,0,0;QS=3,0;MQSB=0.82403;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,205:7:0 0,18,205:6:0 +17 535 . A 0 . DP=31;I16=24,6,0,0,1080,39870,0,0,1777,105769,0,0,611,13341,0,0;QS=3,0;MQSB=0.82403;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,194:7:0 0,18,189:6:0 +17 536 . C 0 . DP=31;I16=24,7,0,0,1097,40707,0,0,1837,109369,0,0,631,13809,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,184:7:0 0,18,157:6:0 +17 537 . C 0 . DP=31;I16=22,7,0,0,1034,38564,0,0,1717,102169,0,0,587,12861,0,0;QS=3,0;MQSB=0.854582;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,172:7:0 0,18,183:6:0 +17 538 . A 0 . DP=31;I16=24,7,0,0,1138,42478,0,0,1837,109369,0,0,620,13536,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,189:7:0 0,18,181:6:0 +17 539 . T 0 . DP=31;I16=24,7,0,0,1134,42070,0,0,1837,109369,0,0,614,13422,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,178:7:0 0,18,181:6:0 +17 540 . C 0 . DP=31;I16=24,7,0,0,1148,43768,0,0,1837,109369,0,0,608,13340,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,177:7:0 0,18,178:6:0 +17 541 . A 0 . DP=32;I16=24,6,0,0,1083,40483,0,0,1777,105769,0,0,551,11991,0,0;QS=3,0;MQSB=0.82403;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,180:8:0 0,15,150:5:0 +17 542 . C 0 . DP=33;I16=25,6,0,0,1123,41759,0,0,1837,109369,0,0,570,12552,0,0;QS=3,0;MQSB=0.822578;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,172:8:0 0,18,174:6:0 +17 543 . C 0 . DP=34;I16=25,9,0,0,1219,45959,0,0,1986,117410,0,0,601,13245,0,0;QS=3,0;MQSB=0.621145;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,27,194:9:0 0,18,188:6:0 +17 544 . A 0 . DP=33;I16=24,8,0,0,1170,43898,0,0,1866,110210,0,0,570,12506,0,0;QS=3,0;MQSB=0.579578;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,192:8:0 0,18,180:6:0 +17 545 . A 0 . DP=33;I16=25,8,0,0,1174,43602,0,0,1926,113810,0,0,587,12951,0,0;QS=3,0;MQSB=0.576102;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,190:8:0 0,18,184:6:0 +17 546 . A 0 . DP=32;I16=24,8,0,0,1126,41444,0,0,1866,110210,0,0,580,12802,0,0;QS=3,0;MQSB=0.579578;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,166:7:0 0,18,193:6:0 +17 547 . A 0 . DP=32;I16=24,7,0,0,1129,42381,0,0,1806,106610,0,0,547,12009,0,0;QS=3,0;MQSB=0.525788;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,180:7:0 0,18,195:6:0 +17 548 . A 0 . DP=33;I16=23,9,0,0,1153,42673,0,0,1866,110210,0,0,561,12489,0,0;QS=3,0;MQSB=0.628357;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,181:7:0 0,21,211:7:0 +17 549 . T G, 0 . DP=32;I16=22,8,0,1,1101,40987,20,400,1746,103010,60,3600,530,11716,25,625;QS=2.96748,0.0325203,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.632337;BQB=1;MQ0F=0 PL:DP:DV 0,31,255,48,255,255:17:1 0,21,168,21,168,168:7:0 0,21,208,21,208,208:7:0 +17 550 . T 0 . DP=32;I16=22,9,0,0,1052,37298,0,0,1806,106610,0,0,548,12176,0,0;QS=3,0;MQSB=0.632337;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,150:7:0 0,21,220:7:0 +17 551 . G 0 . DP=31;I16=22,9,0,0,1121,41639,0,0,1806,106610,0,0,541,12045,0,0;QS=3,0;MQSB=0.632337;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,172:7:0 0,21,208:7:0 +17 552 . C 0 . DP=30;I16=21,9,0,0,1093,41365,0,0,1746,103010,0,0,535,11947,0,0;QS=3,0;MQSB=0.636601;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,167:7:0 0,21,208:7:0 +17 553 . A 0 . DP=30;I16=20,8,0,0,981,35387,0,0,1626,95810,0,0,485,10831,0,0;QS=3,0;MQSB=0.596163;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,150:6:0 0,21,194:7:0 +17 554 . A 0 . DP=30;I16=19,9,0,0,975,35601,0,0,1626,95810,0,0,488,10906,0,0;QS=3,0;MQSB=0.646113;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,139:5:0 0,24,211:8:0 +17 555 . A 0 . DP=30;I16=20,10,0,0,1024,36526,0,0,1746,103010,0,0,514,11392,0,0;QS=3,0;MQSB=0.679025;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,150:6:0 0,21,211:7:0 +17 556 . C 0 . DP=29;I16=20,9,0,0,1055,39195,0,0,1709,101641,0,0,509,11219,0,0;QS=3,0;MQSB=0.894839;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,158:6:0 0,18,186:6:0 +17 557 . A 0 . DP=27;I16=18,9,0,0,987,36749,0,0,1589,94441,0,0,506,11074,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,157:6:0 0,18,186:6:0 +17 558 . A 0 . DP=27;I16=18,8,0,0,948,35808,0,0,1560,93600,0,0,477,10281,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,143:5:0 0,18,177:6:0 +17 559 . C A, 0 . DP=27;I16=17,8,0,1,908,33726,14,196,1500,90000,29,841,448,9516,25,625;QS=2.92708,0.0729167,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.90038;BQB=1;MQ0F=0 PL:DP:DV 0,42,255,42,255,255:14:0 0,4,116,15,119,123:6:1 0,18,169,18,169,169:6:0 +17 560 . C 0 . DP=28;I16=19,9,0,0,992,36552,0,0,1649,98041,0,0,494,10654,0,0;QS=3,0;MQSB=0.896555;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,160:6:0 0,21,181:7:0 +17 561 . A 0 . DP=28;I16=18,9,0,0,963,35455,0,0,1589,94441,0,0,466,9946,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,158:6:0 0,21,194:7:0 +17 562 . C 0 . DP=28;I16=18,9,0,0,1006,38392,0,0,1589,94441,0,0,463,9893,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,153:6:0 0,21,187:7:0 +17 563 . A 0 . DP=27;I16=17,9,0,0,893,32413,0,0,1529,90841,0,0,460,9820,0,0;QS=3,0;MQSB=0.90038;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,149:5:0 0,21,179:7:0 +17 564 . C 0 . DP=27;I16=18,9,0,0,859,28747,0,0,1589,94441,0,0,482,10402,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,121:5:0 0,21,182:7:0 +17 565 . G 0 . DP=30;I16=17,9,0,0,818,26928,0,0,1560,93600,0,0,454,9764,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,96:4:0 0,21,154:7:0 +17 566 . C 0 . DP=29;I16=15,11,0,0,903,33405,0,0,1529,90841,0,0,424,9084,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,155:5:0 0,18,167:6:0 +17 567 . C 0 . DP=30;I16=15,12,0,0,932,33774,0,0,1589,94441,0,0,462,10178,0,0;QS=3,0;MQSB=0.935229;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,155:5:0 0,21,196:7:0 +17 568 . C 0 . DP=29;I16=15,13,0,0,1057,40817,0,0,1649,98041,0,0,482,10438,0,0;QS=3,0;MQSB=0.942064;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,183:6:0 0,18,189:6:0 +17 569 . T 0 . DP=30;I16=16,12,0,0,1056,41296,0,0,1649,98041,0,0,493,10655,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,190:6:0 0,21,213:7:0 +17 570 . T 0 . DP=30;I16=16,12,0,0,954,34972,0,0,1680,100800,0,0,472,10086,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,157:5:0 0,21,195:7:0 +17 571 . C 0 . DP=31;I16=17,12,0,0,1061,40675,0,0,1740,104400,0,0,472,10158,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,155:5:0 0,21,193:7:0 +17 572 . A 0 . DP=31;I16=18,12,0,0,1102,42642,0,0,1769,105241,0,0,499,10887,0,0;QS=3,0;MQSB=0.929991;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,203:7:0 0,18,175:6:0 +17 573 . A 0 . DP=31;I16=18,12,0,0,1057,38473,0,0,1769,105241,0,0,501,10975,0,0;QS=3,0;MQSB=0.929991;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,199:7:0 0,18,178:6:0 +17 574 . C A, 0 . DP=31;I16=18,11,0,1,1088,41328,15,225,1740,104400,29,841,478,10422,25,625;QS=2.94071,0.0592885,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.929991;BQB=1;MQ0F=0 PL:DP:DV 0,48,255,48,255,255:16:0 0,9,170,21,173,177:8:1 0,18,173,18,173,173:6:0 +17 575 . T 0 . DP=30;I16=16,10,0,0,1024,41260,0,0,1560,93600,0,0,448,9842,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,209:7:0 0,15,163:5:0 +17 576 . G 0 . DP=30;I16=17,12,0,0,1047,40077,0,0,1709,101641,0,0,507,11087,0,0;QS=3,0;MQSB=0.931617;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,208:8:0 0,15,151:5:0 +17 577 . G 0 . DP=30;I16=16,12,0,0,999,37747,0,0,1649,98041,0,0,489,10755,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,204:8:0 0,15,146:5:0 +17 578 . G 0 . DP=29;I16=16,13,0,0,975,34803,0,0,1709,101641,0,0,520,11286,0,0;QS=3,0;MQSB=0.940317;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,198:8:0 0,15,151:5:0 +17 579 . G 0 . DP=30;I16=15,13,0,0,1028,38752,0,0,1649,98041,0,0,484,10514,0,0;QS=3,0;MQSB=0.942064;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,224:8:0 0,12,145:4:0 +17 580 . A C, 0 . DP=30;I16=15,14,1,0,1060,39178,16,256,1709,101641,60,3600,510,11078,17,289;QS=2.97338,0.0266223,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.946202;BQB=1;MQ0F=0 PL:DP:DV 0,34,255,48,255,255:17:1 0,24,221,24,221,221:8:0 0,15,155,15,155,155:5:0 +17 581 . A 0 . DP=31;I16=16,15,0,0,1083,39215,0,0,1829,108841,0,0,530,11384,0,0;QS=3,0;MQSB=0.951229;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,223:8:0 0,15,153:5:0 +17 582 . C 0 . DP=31;I16=15,15,0,0,1080,39870,0,0,1769,105241,0,0,519,11211,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,207:8:0 0,15,151:5:0 +17 583 . T 0 . DP=30;I16=16,14,0,0,1136,43996,0,0,1769,105241,0,0,539,11523,0,0;QS=3,0;MQSB=0.946202;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,238:8:0 0,15,163:5:0 +17 584 . C 0 . DP=31;I16=16,13,0,0,1051,39351,0,0,1709,101641,0,0,499,10619,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,207:7:0 0,15,157:5:0 +17 585 . A 0 . DP=31;I16=17,14,0,0,1096,39866,0,0,1798,106082,0,0,549,11751,0,0;QS=3,0;MQSB=0.998229;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,211:8:0 0,15,157:5:0 +17 586 . T 0 . DP=31;I16=16,14,0,0,1081,39839,0,0,1738,102482,0,0,546,11796,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,212:8:0 0,15,156:5:0 +17 587 . C 0 . DP=31;I16=17,13,0,0,1070,39402,0,0,1769,105241,0,0,532,11350,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,201:7:0 0,15,155:5:0 +17 588 . A 0 . DP=31;I16=17,14,0,0,1126,41642,0,0,1798,106082,0,0,562,12140,0,0;QS=3,0;MQSB=0.998229;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,222:8:0 0,15,164:5:0 +17 589 . A 0 . DP=31;I16=17,14,0,0,1157,43973,0,0,1798,106082,0,0,568,12340,0,0;QS=3,0;MQSB=0.998229;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,236:8:0 0,15,165:5:0 +17 590 . C 0 . DP=32;I16=16,14,0,0,1094,41302,0,0,1769,105241,0,0,549,11951,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,192:6:0 0,18,175:6:0 +17 591 . A 0 . DP=31;I16=16,15,0,0,1165,44163,0,0,1798,106082,0,0,579,12695,0,0;QS=3,0;MQSB=0.999805;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,209:7:0 0,18,188:6:0 +17 592 . A 0 . DP=31;I16=15,15,0,0,1114,42144,0,0,1738,102482,0,0,571,12651,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,215:7:0 0,18,182:6:0 +17 593 . C 0 . DP=31;I16=15,14,0,0,1065,39889,0,0,1709,101641,0,0,550,12132,0,0;QS=3,0;MQSB=0.954405;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,191:6:0 0,18,174:6:0 +17 594 . A 0 . DP=33;I16=16,16,0,0,1163,42917,0,0,1858,109682,0,0,572,12672,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,205:7:0 0,24,212:8:0 +17 595 . A 0 . DP=33;I16=17,16,0,0,1130,39996,0,0,1918,113282,0,0,589,12905,0,0;QS=3,0;MQSB=0.999838;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,198:7:0 0,24,213:8:0 +17 596 . A 0 . DP=33;I16=16,16,0,0,1059,37039,0,0,1858,109682,0,0,590,12952,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,169:7:0 0,24,230:8:0 +17 597 . C 0 . DP=33;I16=17,16,0,0,1196,44890,0,0,1918,113282,0,0,592,12990,0,0;QS=3,0;MQSB=0.999838;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,204:7:0 0,24,220:8:0 +17 598 . T 0 . DP=33;I16=16,16,0,0,1214,47104,0,0,1858,109682,0,0,593,13013,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,217:7:0 0,24,239:8:0 +17 599 . T 0 . DP=33;I16=16,17,0,0,1183,43669,0,0,1918,113282,0,0,599,13095,0,0;QS=3,0;MQSB=0.999838;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,197:7:0 0,27,247:9:0 +17 600 . G 0 . DP=32;I16=15,17,0,0,1174,44066,0,0,1858,109682,0,0,601,13145,0,0;QS=3,0;MQSB=0.999287;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,194:7:0 0,24,232:8:0 +17 601 . T 0 . DP=32;I16=15,17,0,0,1114,39954,0,0,1858,109682,0,0,603,13227,0,0;QS=3,0;MQSB=0.999287;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,188:7:0 0,24,235:8:0 +17 602 . G 0 . DP=32;I16=15,15,0,0,1090,40326,0,0,1769,105241,0,0,555,12091,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,185:6:0 0,24,229:8:0 +17 603 . G 0 . DP=31;I16=15,16,0,0,1052,37460,0,0,1798,106082,0,0,607,13437,0,0;QS=3,0;MQSB=0.999805;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,186:7:0 0,24,219:8:0 +17 604 . T 0 . DP=31;I16=14,16,0,0,1009,35893,0,0,1769,105241,0,0,564,12540,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,195:8:0 0,21,212:7:0 +17 605 . T 0 . DP=31;I16=12,15,0,0,1001,37741,0,0,1589,94441,0,0,514,11258,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,200:7:0 0,21,214:7:0 +17 606 . T 0 . DP=31;I16=13,16,0,0,992,35202,0,0,1709,101641,0,0,587,13125,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,189:7:0 0,24,217:8:0 +17 607 . A 0 . DP=31;I16=14,16,0,0,1027,36129,0,0,1738,102482,0,0,607,13577,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,176:7:0 0,24,222:8:0 +17 608 . C 0 . DP=32;I16=15,15,0,0,983,33775,0,0,1769,105241,0,0,564,12564,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,178:7:0 0,27,214:9:0 +17 609 . C 0 . DP=32;I16=14,17,0,0,1074,38220,0,0,1798,106082,0,0,606,13678,0,0;QS=3,0;MQSB=0.998229;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,190:7:0 0,27,238:9:0 +17 610 . C 0 . DP=32;I16=15,16,0,0,1158,44218,0,0,1829,108841,0,0,594,13444,0,0;QS=3,0;MQSB=0.951229;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,211:8:0 0,27,246:9:0 +17 611 . A 0 . DP=32;I16=15,16,0,0,1080,39204,0,0,1798,106082,0,0,590,13260,0,0;QS=3,0;MQSB=0.999805;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,220:9:0 0,27,246:9:0 +17 612 . C 0 . DP=33;I16=16,17,0,0,1175,43305,0,0,1918,113282,0,0,617,13993,0,0;QS=3,0;MQSB=0.999838;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,214:9:0 0,27,250:9:0 +17 613 . A 0 . DP=34;I16=16,17,0,0,1131,40011,0,0,1949,116041,0,0,604,13874,0,0;QS=3,0;MQSB=0.954207;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,223:9:0 0,27,239:9:0 +17 614 . C 0 . DP=34;I16=16,17,0,0,1183,43743,0,0,1949,116041,0,0,608,14022,0,0;QS=3,0;MQSB=0.954207;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,223:9:0 0,27,245:9:0 +17 615 . A 0 . DP=34;I16=16,18,0,0,1199,43809,0,0,1978,116882,0,0,626,14394,0,0;QS=3,0;MQSB=0.999405;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,30,240:10:0 0,27,254:9:0 +17 616 . A 0 . DP=34;I16=16,17,0,0,1190,44024,0,0,1949,116041,0,0,615,14351,0,0;QS=3,0;MQSB=0.954207;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,247:9:0 0,27,255:9:0 +17 617 . T 0 . DP=33;I16=15,18,0,0,1170,43066,0,0,1918,113282,0,0,630,14624,0,0;QS=3,0;MQSB=0.998531;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,30,241:10:0 0,27,255:9:0 +17 618 . G 0 . DP=34;I16=15,19,0,0,1166,41452,0,0,1978,116882,0,0,632,14706,0,0;QS=3,0;MQSB=0.997597;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,30,248:10:0 0,27,240:9:0 +17 619 . G 0 . DP=32;I16=14,18,0,0,1153,42591,0,0,1858,109682,0,0,638,14816,0,0;QS=3,0;MQSB=0.997118;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,30,254:10:0 0,27,247:9:0 +17 620 . A 0 . DP=32;I16=14,17,0,0,1083,39757,0,0,1798,106082,0,0,616,14176,0,0;QS=3,0;MQSB=0.998229;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,30,248:10:0 0,27,255:9:0 +17 621 . A 0 . DP=32;I16=13,18,0,0,1170,45248,0,0,1798,106082,0,0,627,14519,0,0;QS=3,0;MQSB=0.995005;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,255:9:0 0,27,255:9:0 +17 622 . G 0 . DP=32;I16=12,18,0,0,1060,39160,0,0,1769,105241,0,0,604,13888,0,0;QS=3,0;MQSB=0.968257;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,236:9:0 0,27,249:9:0 +17 623 . A T, 0 . DP=32;I16=10,18,1,0,1010,37414,15,225,1649,98041,60,3600,563,12953,25,625;QS=2.96144,0.0385604,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.969907;BQB=1;MQ0F=0 PL:DP:DV 0,20,241,33,244,246:12:1 0,24,213,24,213,213:8:0 0,27,255,27,255,255:9:0 +17 624 . C 0 . DP=32;I16=13,17,0,0,1034,37292,0,0,1738,102482,0,0,607,13887,0,0;QS=3,0;MQSB=0.996503;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,220:9:0 0,27,242:9:0 +17 625 . C 0 . DP=32;I16=13,18,0,0,1108,41138,0,0,1798,106082,0,0,632,14470,0,0;QS=3,0;MQSB=0.995005;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,234:9:0 0,27,249:9:0 +17 626 . A 0 . DP=32;I16=13,17,0,0,1090,40718,0,0,1738,102482,0,0,607,13827,0,0;QS=3,0;MQSB=0.996503;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,237:9:0 0,27,247:9:0 +17 627 . C 0 . DP=32;I16=12,18,0,0,1146,44452,0,0,1769,105241,0,0,607,13833,0,0;QS=3,0;MQSB=0.968257;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,244:9:0 0,27,255:9:0 +17 628 . T 0 . DP=32;I16=11,19,0,0,1124,43114,0,0,1769,105241,0,0,608,13862,0,0;QS=3,0;MQSB=0.972375;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,249:9:0 0,24,249:8:0 +17 629 . T 0 . DP=32;I16=12,19,0,0,1114,41138,0,0,1798,106082,0,0,634,14490,0,0;QS=3,0;MQSB=0.989977;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,247:9:0 0,24,226:8:0 +17 630 . A 0 . DP=31;I16=11,18,0,0,1101,42885,0,0,1740,104400,0,0,610,13844,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,242:8:0 0,24,235:8:0 +17 631 . G 0 . DP=31;I16=12,18,0,0,1083,40525,0,0,1769,105241,0,0,636,14474,0,0;QS=3,0;MQSB=0.929991;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,233:8:0 0,24,223:8:0 +17 632 . C 0 . DP=31;I16=11,18,0,0,1105,42665,0,0,1740,104400,0,0,612,13880,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,233:8:0 0,24,224:8:0 +17 633 . A 0 . DP=31;I16=12,18,0,0,1056,38190,0,0,1769,105241,0,0,638,14562,0,0;QS=3,0;MQSB=0.929991;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,218:8:0 0,24,214:8:0 +17 634 . A 0 . DP=31;I16=12,18,0,0,1110,42208,0,0,1769,105241,0,0,638,14594,0,0;QS=3,0;MQSB=0.929991;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,238:8:0 0,24,229:8:0 +17 635 . C 0 . DP=31;I16=11,18,0,0,1031,37871,0,0,1740,104400,0,0,613,14025,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,220:8:0 0,24,229:8:0 +17 636 . A 0 . DP=31;I16=11,18,0,0,1115,43327,0,0,1740,104400,0,0,611,14005,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,228:8:0 0,24,243:8:0 +17 637 . A 0 . DP=31;I16=12,18,0,0,1152,44602,0,0,1769,105241,0,0,634,14634,0,0;QS=3,0;MQSB=0.929991;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,238:8:0 0,24,242:8:0 +17 638 . A 0 . DP=31;I16=12,18,0,0,1118,42406,0,0,1769,105241,0,0,631,14611,0,0;QS=3,0;MQSB=0.929991;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,235:8:0 0,24,238:8:0 +17 639 . A 0 . DP=30;I16=11,18,0,0,1037,38233,0,0,1709,101641,0,0,602,13934,0,0;QS=3,0;MQSB=0.921439;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,230:8:0 0,24,227:8:0 +17 640 . A 0 . DP=31;I16=11,19,0,0,1154,45368,0,0,1769,105241,0,0,596,13804,0,0;QS=3,0;MQSB=0.91982;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,242:8:0 0,24,240:8:0 +17 641 . G 0 . DP=31;I16=11,19,0,0,1018,36496,0,0,1769,105241,0,0,590,13650,0,0;QS=3,0;MQSB=0.91982;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,214:8:0 0,24,218:8:0 +17 642 . G 0 . DP=30;I16=11,19,0,0,1057,38459,0,0,1769,105241,0,0,610,14148,0,0;QS=3,0;MQSB=0.91982;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,187:7:0 0,24,221:8:0 +17 643 . A 0 . DP=29;I16=11,17,0,0,969,35477,0,0,1649,98041,0,0,585,13605,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,199:7:0 0,24,237:8:0 +17 644 . C A, 0 . DP=29;I16=9,18,1,0,898,30864,17,289,1620,97200,60,3600,549,12567,25,625;QS=2.95685,0.0431472,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,22,236,36,239,243:13:1 0,21,195,21,195,195:7:0 0,24,204,24,204,204:8:0 +17 645 . C 0 . DP=30;I16=10,19,0,0,1067,40337,0,0,1709,101641,0,0,584,13274,0,0;QS=3,0;MQSB=0.909373;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,198:7:0 0,24,226:8:0 +17 646 . A T, 0 . DP=31;I16=9,20,1,0,1044,38174,14,196,1740,104400,60,3600,553,12499,25,625;QS=2.97113,0.028866,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,27,255,39,255,255:14:1 0,21,197,21,197,197:7:0 0,27,229,27,229,229:9:0 +17 647 . A 0 . DP=33;I16=10,21,0,0,1041,35883,0,0,1829,108841,0,0,573,12999,0,0;QS=3,0;MQSB=0.906252;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,189:7:0 0,30,213:10:0 +17 648 . A 0 . DP=33;I16=11,22,0,0,1030,34122,0,0,1949,116041,0,0,594,13478,0,0;QS=3,0;MQSB=0.915545;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,188:7:0 0,30,194:10:0 +17 649 . C 0 . DP=32;I16=10,21,0,0,1099,39879,0,0,1860,111600,0,0,566,12738,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,188:7:0 0,27,217:9:0 +17 650 . T 0 . DP=31;I16=11,18,0,0,1006,37114,0,0,1709,101641,0,0,549,12407,0,0;QS=3,0;MQSB=0.921439;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,187:6:0 0,24,226:8:0 +17 651 . C 0 . DP=32;I16=11,20,0,0,1117,41181,0,0,1829,108841,0,0,581,13107,0,0;QS=3,0;MQSB=0.918304;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,186:6:0 0,27,229:9:0 +17 652 . C 0 . DP=32;I16=9,21,0,0,1126,43084,0,0,1769,105241,0,0,557,12423,0,0;QS=3,0;MQSB=0.893237;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,196:6:0 0,24,213:8:0 +17 653 . T 0 . DP=33;I16=9,23,0,0,1141,42631,0,0,1889,112441,0,0,556,12382,0,0;QS=3,0;MQSB=0.890331;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,198:6:0 0,24,225:8:0 +17 654 . G 0 . DP=33;I16=10,23,0,0,1171,43025,0,0,1949,116041,0,0,578,12798,0,0;QS=3,0;MQSB=0.903508;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,191:6:0 0,24,223:8:0 +17 655 . G 0 . DP=32;I16=10,22,0,0,1118,40202,0,0,1889,112441,0,0,575,12573,0,0;QS=3,0;MQSB=0.904837;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,181:6:0 0,24,213:8:0 +17 656 . T 0 . DP=32;I16=10,22,0,0,1090,38566,0,0,1889,112441,0,0,571,12333,0,0;QS=3,0;MQSB=0.904837;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,185:6:0 0,24,213:8:0 +17 657 . A 0 . DP=32;I16=10,21,0,0,1100,40006,0,0,1829,108841,0,0,557,12029,0,0;QS=3,0;MQSB=0.906252;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,183:6:0 0,24,191:8:0 +17 658 . C 0 . DP=32;I16=10,21,0,0,1115,41039,0,0,1829,108841,0,0,542,11520,0,0;QS=3,0;MQSB=0.906252;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,168:5:0 0,24,211:8:0 +17 659 . A 0 . DP=32;I16=10,21,0,0,1141,42897,0,0,1829,108841,0,0,547,11685,0,0;QS=3,0;MQSB=0.906252;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,191:6:0 0,24,216:8:0 +17 660 . T 0 . DP=33;I16=10,22,0,0,1139,41887,0,0,1889,112441,0,0,553,11659,0,0;QS=3,0;MQSB=0.904837;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,186:6:0 0,24,214:8:0 +17 661 . G 0 . DP=32;I16=9,22,0,0,1107,41531,0,0,1829,108841,0,0,549,11549,0,0;QS=3,0;MQSB=0.891738;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,191:6:0 0,21,188:7:0 +17 662 . C 0 . DP=32;I16=8,22,0,0,1087,40811,0,0,1800,108000,0,0,523,10991,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,192:6:0 0,21,187:7:0 +17 663 . A 0 . DP=32;I16=9,22,0,0,1036,36816,0,0,1829,108841,0,0,540,11388,0,0;QS=3,0;MQSB=0.891738;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,192:6:0 0,21,186:7:0 +17 664 . A 0 . DP=32;I16=9,23,0,0,1125,40759,0,0,1889,112441,0,0,552,11628,0,0;QS=3,0;MQSB=0.890331;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,188:6:0 0,21,184:7:0 +17 665 . C 0 . DP=30;I16=9,21,0,0,1075,39697,0,0,1769,105241,0,0,550,11650,0,0;QS=3,0;MQSB=0.893237;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,186:6:0 0,21,184:7:0 +17 666 . T 0 . DP=29;I16=9,20,0,0,1096,41946,0,0,1709,101641,0,0,547,11607,0,0;QS=3,0;MQSB=0.894839;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,171:5:0 0,21,194:7:0 +17 667 . G 0 . DP=31;I16=11,19,0,0,1037,37627,0,0,1769,105241,0,0,524,11198,0,0;QS=3,0;MQSB=0.91982;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,189:6:0 0,21,188:7:0 +17 668 . A 0 . DP=31;I16=11,20,0,0,1102,39980,0,0,1829,108841,0,0,543,11625,0,0;QS=3,0;MQSB=0.918304;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,190:6:0 0,21,187:7:0 +17 669 . C 0 . DP=30;I16=10,19,0,0,1051,38869,0,0,1740,104400,0,0,528,11464,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,182:6:0 0,21,189:7:0 +17 670 . A 0 . DP=30;I16=11,19,0,0,1121,43423,0,0,1769,105241,0,0,540,11642,0,0;QS=3,0;MQSB=0.91982;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,194:6:0 0,21,205:7:0 +17 671 . G 0 . DP=30;I16=11,19,0,0,1101,41035,0,0,1769,105241,0,0,537,11637,0,0;QS=3,0;MQSB=0.91982;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,181:6:0 0,21,191:7:0 +17 672 . A 0 . DP=30;I16=10,19,0,0,1031,37795,0,0,1740,104400,0,0,521,11479,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,185:6:0 0,21,185:7:0 +17 673 . T 0 . DP=29;I16=8,19,0,0,954,34984,0,0,1589,94441,0,0,497,10885,0,0;QS=3,0;MQSB=0.880529;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,126:4:0 0,21,192:7:0 +17 674 . G 0 . DP=29;I16=10,18,0,0,974,35736,0,0,1649,98041,0,0,497,10827,0,0;QS=3,0;MQSB=0.911099;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,146:5:0 0,21,185:7:0 +17 675 . A 0 . DP=28;I16=9,19,0,0,996,36338,0,0,1649,98041,0,0,517,11389,0,0;QS=3,0;MQSB=0.896555;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,124:4:0 0,21,189:7:0 +17 676 . A 0 . DP=29;I16=8,19,0,0,988,36578,0,0,1589,94441,0,0,462,10106,0,0;QS=3,0;MQSB=0.880529;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,128:4:0 0,21,186:7:0 +17 677 . T 0 . DP=29;I16=9,20,0,0,1006,36126,0,0,1709,101641,0,0,507,11303,0,0;QS=3,0;MQSB=0.894839;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,120:4:0 0,21,192:7:0 +17 678 . C 0 . DP=29;I16=9,20,0,0,1020,36984,0,0,1709,101641,0,0,502,11280,0,0;QS=3,0;MQSB=0.894839;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,117:4:0 0,21,191:7:0 +17 679 . T 0 . DP=27;I16=6,19,0,0,902,33612,0,0,1469,87241,0,0,460,10414,0,0;QS=3,0;MQSB=0.833024;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,96:3:0 0,21,195:7:0 +17 680 . C 0 . DP=26;I16=7,18,0,0,879,32295,0,0,1469,87241,0,0,468,10482,0,0;QS=3,0;MQSB=0.862128;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,98:3:0 0,21,181:7:0 +17 681 . A 0 . DP=27;I16=7,17,0,0,844,30190,0,0,1409,83641,0,0,465,10425,0,0;QS=3,0;MQSB=0.864405;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,106:3:0 0,21,174:7:0 +17 682 . A 0 . DP=27;I16=7,20,0,0,919,32179,0,0,1589,94441,0,0,500,11096,0,0;QS=3,0;MQSB=0.858077;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,145:5:0 0,21,176:7:0 +17 683 . A 0 . DP=29;I16=8,21,0,0,949,32735,0,0,1709,101641,0,0,499,11103,0,0;QS=3,0;MQSB=0.876998;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,172:6:0 0,21,167:7:0 +17 684 . C 0 . DP=29;I16=6,21,0,0,802,24468,0,0,1589,94441,0,0,473,10459,0,0;QS=3,0;MQSB=0.829029;MQ0F=0 PL:DP:DV 0,45,251:15:0 0,15,118:5:0 0,21,145:7:0 +17 685 . G 0 . DP=28;I16=6,21,0,0,908,32092,0,0,1620,97200,0,0,498,11090,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,130:5:0 0,21,175:7:0 +17 686 . C 0 . DP=28;I16=7,21,0,0,977,35493,0,0,1680,100800,0,0,500,11080,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,170:6:0 0,21,180:7:0 +17 687 . A 0 . DP=28;I16=6,20,0,0,900,31952,0,0,1560,93600,0,0,475,10469,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,175:6:0 0,21,174:7:0 +17 688 . T 0 . DP=27;I16=6,21,0,0,937,33971,0,0,1620,97200,0,0,501,11135,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,153:6:0 0,21,187:7:0 +17 689 . T A, 0 . DP=27;I16=5,20,1,0,829,28967,13,169,1500,90000,60,3600,463,10359,25,625;QS=2.97105,0.0289532,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,28,231,39,234,234:14:1 0,15,116,15,116,116:5:0 0,21,185,21,185,185:7:0 +17 690 . C 0 . DP=27;I16=6,20,0,0,935,34553,0,0,1560,93600,0,0,486,10974,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,146:5:0 0,21,165:7:0 +17 691 . C 0 . DP=26;I16=5,18,0,0,842,31906,0,0,1380,82800,0,0,446,10166,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,129:4:0 0,18,161:6:0 +17 692 . T 0 . DP=26;I16=6,19,0,0,886,32434,0,0,1500,90000,0,0,486,11082,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,146:5:0 0,18,164:6:0 +17 693 . C 0 . DP=27;I16=6,20,0,0,891,31839,0,0,1560,93600,0,0,483,11007,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,141:5:0 0,21,172:7:0 +17 694 . C 0 . DP=27;I16=6,21,0,0,808,25004,0,0,1620,97200,0,0,498,11248,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,242:14:0 0,18,136:6:0 0,21,146:7:0 +17 695 . G 0 . DP=25;I16=4,20,0,0,807,28037,0,0,1440,86400,0,0,476,10692,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,246:13:0 0,18,145:6:0 0,15,124:5:0 +17 696 . T 0 . DP=25;I16=5,20,0,0,896,32870,0,0,1500,90000,0,0,499,11129,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,150:6:0 0,15,141:5:0 +17 697 . G 0 . DP=26;I16=5,19,0,0,852,30594,0,0,1409,83641,0,0,450,9858,0,0;QS=3,0;MQSB=0.796124;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,142:5:0 0,15,120:5:0 +17 698 . T 0 . DP=27;I16=6,20,0,0,917,33201,0,0,1529,90841,0,0,502,11114,0,0;QS=3,0;MQSB=0.83095;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,154:6:0 0,15,131:5:0 +17 699 . G 0 . DP=28;I16=5,21,0,0,923,34103,0,0,1529,90841,0,0,498,10884,0,0;QS=3,0;MQSB=0.79189;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,163:6:0 0,15,132:5:0 +17 700 . A 0 . DP=28;I16=6,22,0,0,989,35833,0,0,1618,95282,0,0,530,11626,0,0;QS=3,0;MQSB=0.904554;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,169:7:0 0,18,148:6:0 +17 701 . A 0 . DP=29;I16=5,23,0,0,992,35956,0,0,1618,95282,0,0,517,11459,0,0;QS=3,0;MQSB=0.864394;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,186:7:0 0,18,144:6:0 +17 702 . A 0 . DP=29;I16=5,23,0,0,1103,44105,0,0,1618,95282,0,0,520,11508,0,0;QS=3,0;MQSB=0.864394;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,204:7:0 0,18,159:6:0 +17 703 . G 0 . DP=29;I16=5,23,0,0,1014,37508,0,0,1618,95282,0,0,522,11534,0,0;QS=3,0;MQSB=0.864394;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,172:7:0 0,18,144:6:0 +17 704 . A T, 0 . DP=29;I16=4,23,1,0,954,34200,16,256,1558,91682,60,3600,499,10963,13,169;QS=2.97064,0.0293578,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.864394;BQB=1;MQ0F=0 PL:DP:DV 0,31,255,45,255,255:16:1 0,18,154,18,154,154:6:0 0,18,139,18,139,139:6:0 +17 705 . A 0 . DP=29;I16=6,22,0,0,1042,39930,0,0,1618,95282,0,0,513,11189,0,0;QS=3,0;MQSB=0.904554;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,189:7:0 0,18,157:6:0 +17 706 . G 0 . DP=30;I16=6,23,0,0,1029,37763,0,0,1678,98882,0,0,513,11225,0,0;QS=3,0;MQSB=0.900586;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,170:7:0 0,18,131:6:0 +17 707 . C 0 . DP=30;I16=5,22,0,0,944,34494,0,0,1558,91682,0,0,464,10040,0,0;QS=3,0;MQSB=0.868709;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,131:5:0 0,18,134:6:0 +17 708 . C 0 . DP=30;I16=6,24,0,0,898,27574,0,0,1738,102482,0,0,540,12010,0,0;QS=3,0;MQSB=0.896846;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,153:8:0 0,18,110:6:0 +17 709 . G 0 . DP=29;I16=5,22,0,0,968,36130,0,0,1558,91682,0,0,507,11343,0,0;QS=3,0;MQSB=0.868709;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,178:8:0 0,15,132:5:0 +17 710 . G 0 . DP=29;I16=5,23,0,0,961,34825,0,0,1618,95282,0,0,533,12029,0,0;QS=3,0;MQSB=0.864394;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,174:8:0 0,15,122:5:0 +17 711 . A 0 . DP=29;I16=6,23,0,0,996,35700,0,0,1647,96123,0,0,565,12723,0,0;QS=3,0;MQSB=0.957107;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,171:7:0 0,18,142:6:0 +17 712 . C 0 . DP=29;I16=6,23,0,0,1069,40863,0,0,1647,96123,0,0,565,12767,0,0;QS=3,0;MQSB=0.957107;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,156:7:0 0,18,146:6:0 +17 713 . T 0 . DP=29;I16=6,23,0,0,1072,40426,0,0,1647,96123,0,0,565,12835,0,0;QS=3,0;MQSB=0.957107;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,187:7:0 0,18,149:6:0 +17 714 . C 0 . DP=28;I16=6,21,0,0,988,37236,0,0,1558,91682,0,0,541,12301,0,0;QS=3,0;MQSB=0.90877;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,153:6:0 0,15,125:5:0 +17 715 . A 0 . DP=28;I16=6,20,0,0,884,31414,0,0,1498,88082,0,0,522,12004,0,0;QS=3,0;MQSB=0.913254;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,138:6:0 0,15,120:5:0 +17 716 . C 0 . DP=29;I16=4,23,0,0,998,37756,0,0,1527,88923,0,0,547,12501,0,0;QS=3,0;MQSB=0.877203;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,141:5:0 0,18,145:6:0 +17 717 . A 0 . DP=31;I16=8,23,0,0,1136,42928,0,0,1767,103323,0,0,574,13254,0,0;QS=3,0;MQSB=0.987595;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,212:8:0 0,18,153:6:0 +17 718 . G 0 . DP=29;I16=7,22,0,0,1066,40006,0,0,1647,96123,0,0,579,13407,0,0;QS=3,0;MQSB=0.979435;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,223:8:0 0,18,139:6:0 +17 719 . G 0 . DP=29;I16=7,19,0,0,952,35868,0,0,1529,90841,0,0,510,11756,0,0;QS=3,0;MQSB=0.860025;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,204:8:0 0,12,120:4:0 +17 720 . G 0 . DP=28;I16=6,20,0,0,986,37838,0,0,1467,85323,0,0,552,12940,0,0;QS=3,0;MQSB=0.970805;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,216:8:0 0,18,147:6:0 +17 721 . C 0 . DP=28;I16=6,21,0,0,989,36901,0,0,1527,88923,0,0,567,13183,0,0;QS=3,0;MQSB=0.966147;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,197:8:0 0,18,147:6:0 +17 722 . A 0 . DP=28;I16=6,21,0,0,949,33837,0,0,1527,88923,0,0,569,13225,0,0;QS=3,0;MQSB=0.966147;MQ0F=0 PL:DP:DV 0,39,244:13:0 0,24,205:8:0 0,18,143:6:0 +17 723 . A 0 . DP=28;I16=6,19,0,0,925,34825,0,0,1438,84482,0,0,530,12366,0,0;QS=3,0;MQSB=0.918029;MQ0F=0 PL:DP:DV 0,36,253:12:0 0,24,206:8:0 0,15,135:5:0 +17 724 . C 0 . DP=28;I16=5,22,0,0,967,35983,0,0,1527,88923,0,0,566,13028,0,0;QS=3,0;MQSB=0.932273;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,161:7:0 0,18,140:6:0 +17 725 . A 0 . DP=28;I16=6,21,0,0,911,31971,0,0,1527,88923,0,0,565,12987,0,0;QS=3,0;MQSB=0.966147;MQ0F=0 PL:DP:DV 0,42,246:14:0 0,21,168:7:0 0,18,137:6:0 +17 726 . C 0 . DP=28;I16=6,21,0,0,947,34531,0,0,1527,88923,0,0,563,12919,0,0;QS=3,0;MQSB=0.966147;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,166:7:0 0,18,136:6:0 +17 727 . A C, 0 . DP=28;I16=6,20,0,1,904,32194,17,289,1498,88082,29,841,535,12199,25,625;QS=2.90811,0.0918919,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.966147;BQB=1;MQ0F=0 PL:DP:DV 0,42,247,42,247,247:14:0 0,21,191,21,191,191:7:0 0,1,109,15,112,119:6:1 +17 728 . C 0 . DP=29;I16=6,22,0,0,1018,37990,0,0,1587,92523,0,0,557,12701,0,0;QS=3,0;MQSB=0.961573;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,208:8:0 0,18,142:6:0 +17 729 . T 0 . DP=29;I16=7,22,0,0,1063,39315,0,0,1647,96123,0,0,581,13227,0,0;QS=3,0;MQSB=0.979435;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,244:9:0 0,18,142:6:0 +17 730 . A 0 . DP=29;I16=7,21,0,0,993,35883,0,0,1618,95282,0,0,555,12529,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,219:9:0 0,15,135:5:0 +17 731 . T 0 . DP=29;I16=7,22,0,0,1024,37312,0,0,1647,96123,0,0,578,13058,0,0;QS=3,0;MQSB=0.979435;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,210:9:0 0,18,148:6:0 +17 732 . C 0 . DP=29;I16=7,21,0,0,1006,37058,0,0,1618,95282,0,0,550,12314,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,219:9:0 0,15,129:5:0 +17 733 . T 0 . DP=29;I16=7,21,0,0,985,35497,0,0,1618,95282,0,0,547,12221,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,222:9:0 0,15,134:5:0 +17 734 . G 0 . DP=29;I16=7,21,0,0,997,36453,0,0,1587,92523,0,0,544,12154,0,0;QS=3,0;MQSB=0.982906;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,204:8:0 0,18,139:6:0 +17 735 . A 0 . DP=30;I16=7,21,0,0,963,33993,0,0,1618,95282,0,0,515,11437,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,190:8:0 0,18,148:6:0 +17 736 . C 0 . DP=30;I16=8,20,0,0,1042,39326,0,0,1618,95282,0,0,512,11320,0,0;QS=3,0;MQSB=0.954515;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,218:8:0 0,18,152:6:0 +17 737 . T 0 . DP=30;I16=8,22,0,0,1071,39825,0,0,1707,99723,0,0,560,12480,0,0;QS=3,0;MQSB=0.990151;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,243:9:0 0,21,149:7:0 +17 738 . G 0 . DP=30;I16=8,21,0,0,1016,36816,0,0,1678,98882,0,0,533,11793,0,0;QS=3,0;MQSB=0.950946;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,210:9:0 0,18,141:6:0 +17 739 . T 0 . DP=30;I16=7,22,0,0,1020,37326,0,0,1647,96123,0,0,534,11900,0,0;QS=3,0;MQSB=0.979435;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,202:8:0 0,21,155:7:0 +17 740 . T 0 . DP=29;I16=7,21,0,0,1011,37465,0,0,1587,92523,0,0,532,11848,0,0;QS=3,0;MQSB=0.982906;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,232:8:0 0,21,155:7:0 +17 741 . T 0 . DP=29;I16=7,21,0,0,984,36052,0,0,1587,92523,0,0,528,11722,0,0;QS=3,0;MQSB=0.982906;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,224:8:0 0,21,151:7:0 +17 742 . C 0 . DP=30;I16=8,21,0,0,1046,39056,0,0,1678,98882,0,0,525,11671,0,0;QS=3,0;MQSB=0.950946;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,243:9:0 0,18,136:6:0 +17 743 . A 0 . DP=30;I16=8,21,0,0,1026,37156,0,0,1678,98882,0,0,520,11500,0,0;QS=3,0;MQSB=0.950946;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,239:9:0 0,18,131:6:0 +17 744 . T 0 . DP=30;I16=8,22,0,0,1100,41010,0,0,1707,99723,0,0,540,11984,0,0;QS=3,0;MQSB=0.990151;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,247:9:0 0,21,154:7:0 +17 745 . G 0 . DP=31;I16=9,22,0,0,1078,38890,0,0,1767,103323,0,0,535,11873,0,0;QS=3,0;MQSB=0.996219;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,227:9:0 0,24,178:8:0 +17 746 . G 0 . DP=31;I16=9,21,0,0,1001,35191,0,0,1707,99723,0,0,531,11793,0,0;QS=3,0;MQSB=0.997698;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,201:9:0 0,24,178:8:0 +17 747 . G 0 . DP=30;I16=9,20,0,0,1017,36831,0,0,1647,96123,0,0,509,11343,0,0;QS=3,0;MQSB=0.99889;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,201:8:0 0,21,174:7:0 +17 748 . A 0 . DP=30;I16=10,20,0,0,1046,37438,0,0,1707,99723,0,0,529,11721,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,242:9:0 0,18,159:6:0 +17 749 . A 0 . DP=31;I16=10,21,0,0,1077,38303,0,0,1767,103323,0,0,530,11728,0,0;QS=3,0;MQSB=0.999777;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,27,240:9:0 0,18,164:6:0 +17 750 . A 0 . DP=32;I16=10,20,0,0,1129,43093,0,0,1738,102482,0,0,500,11252,0,0;QS=3,0;MQSB=0.976097;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,232:8:0 0,15,161:5:0 +17 751 . G 0 . DP=31;I16=11,20,0,0,1065,37955,0,0,1767,103323,0,0,535,11787,0,0;QS=3,0;MQSB=0.999148;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,27,206:9:0 0,18,150:6:0 +17 752 . T 0 . DP=31;I16=11,20,0,0,1034,35786,0,0,1767,103323,0,0,537,11793,0,0;QS=3,0;MQSB=0.999148;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,27,223:9:0 0,18,143:6:0 +17 753 . C 0 . DP=31;I16=12,19,0,0,1073,38779,0,0,1767,103323,0,0,540,11834,0,0;QS=3,0;MQSB=0.994873;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,30,227:10:0 0,18,158:6:0 +17 754 . T 0 . DP=31;I16=12,19,0,0,1135,42527,0,0,1767,103323,0,0,542,11808,0,0;QS=3,0;MQSB=0.994873;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,30,255:10:0 0,18,172:6:0 +17 755 . G 0 . DP=31;I16=12,19,0,0,1157,43695,0,0,1767,103323,0,0,544,11814,0,0;QS=3,0;MQSB=0.994873;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,30,255:10:0 0,18,162:6:0 +17 756 . G 0 . DP=30;I16=12,17,0,0,1002,35566,0,0,1647,96123,0,0,539,11753,0,0;QS=3,0;MQSB=0.988062;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,30,242:10:0 0,18,157:6:0 +17 757 . A 0 . DP=30;I16=12,17,0,0,1035,37723,0,0,1678,98882,0,0,523,11197,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,30,248:10:0 0,15,152:5:0 +17 758 . A 0 . DP=30;I16=12,18,0,0,1015,35685,0,0,1707,99723,0,0,549,11825,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,30,247:10:0 0,18,156:6:0 +17 759 . A 0 . DP=30;I16=12,16,0,0,998,36498,0,0,1618,95282,0,0,526,11472,0,0;QS=3,0;MQSB=0.995699;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,242:9:0 0,15,151:5:0 +17 760 . C 0 . DP=31;I16=12,18,0,0,916,29466,0,0,1707,99723,0,0,547,11741,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,30,217:10:0 0,18,128:6:0 +17 761 . G 0 . DP=30;I16=11,16,0,0,932,32884,0,0,1589,94441,0,0,512,11028,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,220:9:0 0,15,153:5:0 +17 762 . G 0 . DP=29;I16=11,18,0,0,1012,36984,0,0,1647,96123,0,0,541,11629,0,0;QS=3,0;MQSB=0.995968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,220:9:0 0,21,173:7:0 +17 763 . C A, 0 . DP=29;I16=11,16,0,1,948,35124,15,225,1558,91682,29,841,527,11473,2,4;QS=2.93697,0.0630252,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.993109;BQB=1;MQ0F=0 PL:DP:DV 0,39,255,39,255,255:13:0 0,24,193,24,193,193:8:0 0,6,158,18,161,165:7:1 +17 764 . A 0 . DP=31;I16=12,18,0,0,1051,37737,0,0,1738,102482,0,0,516,11020,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,30,250:10:0 0,18,163:6:0 +17 765 . A 0 . DP=32;I16=12,18,0,0,1071,39369,0,0,1738,102482,0,0,525,11379,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,30,254:10:0 0,18,169:6:0 +17 766 . C 0 . DP=31;I16=13,18,0,0,1065,38285,0,0,1798,106082,0,0,547,11797,0,0;QS=3,0;MQSB=0.995005;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,33,235:11:0 0,18,164:6:0 +17 767 . A 0 . DP=30;I16=12,18,0,0,996,34692,0,0,1738,102482,0,0,552,11926,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,244:11:0 0,18,148:6:0 +17 768 . C 0 . DP=30;I16=12,18,0,0,1095,40739,0,0,1738,102482,0,0,556,12038,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,255:11:0 0,18,173:6:0 +17 769 . C 0 . DP=30;I16=12,18,0,0,1110,42272,0,0,1738,102482,0,0,559,12133,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,255:11:0 0,18,173:6:0 +17 770 . A 0 . DP=30;I16=12,18,0,0,1098,40852,0,0,1738,102482,0,0,562,12262,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,255:11:0 0,18,171:6:0 +17 771 . T 0 . DP=30;I16=12,18,0,0,1111,41771,0,0,1738,102482,0,0,563,12325,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,255:11:0 0,18,177:6:0 +17 772 . T 0 . DP=30;I16=12,18,0,0,1107,41429,0,0,1738,102482,0,0,563,12373,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,255:11:0 0,18,176:6:0 +17 773 . G 0 . DP=30;I16=12,18,0,0,1123,42761,0,0,1738,102482,0,0,562,12406,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,255:11:0 0,18,175:6:0 +17 774 . A 0 . DP=30;I16=12,18,0,0,1151,44801,0,0,1738,102482,0,0,560,12422,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,255:11:0 0,18,179:6:0 +17 775 . G 0 . DP=30;I16=12,18,0,0,1136,43766,0,0,1738,102482,0,0,557,12419,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,255:11:0 0,18,177:6:0 +17 776 . A 0 . DP=29;I16=12,17,0,0,1053,38865,0,0,1678,98882,0,0,553,12345,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,30,255:10:0 0,18,169:6:0 +17 777 . C 0 . DP=28;I16=12,16,0,0,1019,37631,0,0,1618,95282,0,0,550,12298,0,0;QS=3,0;MQSB=0.995699;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,229:9:0 0,18,165:6:0 +17 778 . A 0 . DP=28;I16=12,16,0,0,1079,42041,0,0,1618,95282,0,0,547,12277,0,0;QS=3,0;MQSB=0.995699;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,241:9:0 0,18,181:6:0 +17 779 . G 0 . DP=28;I16=12,16,0,0,1025,38825,0,0,1618,95282,0,0,543,12231,0,0;QS=3,0;MQSB=0.995699;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,231:9:0 0,18,170:6:0 +17 780 . A 0 . DP=28;I16=12,16,0,0,1005,36773,0,0,1618,95282,0,0,538,12160,0,0;QS=3,0;MQSB=0.995699;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,242:9:0 0,18,166:6:0 +17 781 . A 0 . DP=28;I16=12,15,0,0,965,35857,0,0,1589,94441,0,0,519,11889,0,0;QS=3,0;MQSB=0.935229;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,222:8:0 0,15,159:5:0 +17 782 . A 0 . DP=28;I16=12,16,0,0,1003,37315,0,0,1618,95282,0,0,530,12044,0,0;QS=3,0;MQSB=0.995699;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,229:8:0 0,18,171:6:0 +17 783 . A 0 . DP=28;I16=12,16,0,0,989,36477,0,0,1618,95282,0,0,527,12001,0,0;QS=3,0;MQSB=0.995699;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,230:8:0 0,21,178:7:0 +17 784 . C 0 . DP=26;I16=11,15,0,0,967,36387,0,0,1498,88082,0,0,527,11983,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,207:7:0 0,21,178:7:0 +17 785 . A 0 . DP=26;I16=11,15,0,0,989,38499,0,0,1498,88082,0,0,527,11989,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,213:7:0 0,21,187:7:0 +17 786 . G 0 . DP=26;I16=11,14,0,0,938,35698,0,0,1438,84482,0,0,501,11343,0,0;QS=3,0;MQSB=0.996634;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,211:7:0 0,21,180:7:0 +17 787 . G 0 . DP=26;I16=11,15,0,0,914,33428,0,0,1498,88082,0,0,525,11969,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,189:7:0 0,21,175:7:0 +17 788 . T 0 . DP=26;I16=11,15,0,0,913,33357,0,0,1498,88082,0,0,524,11992,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,180:7:0 0,21,188:7:0 +17 789 . G 0 . DP=26;I16=11,15,0,0,963,36645,0,0,1498,88082,0,0,523,12037,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,193:7:0 0,21,183:7:0 +17 790 . A 0 . DP=26;I16=11,15,0,0,999,39113,0,0,1498,88082,0,0,520,12002,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,198:7:0 0,21,201:7:0 +17 791 . G 0 . DP=26;I16=11,15,0,0,934,34208,0,0,1498,88082,0,0,516,11934,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,180:7:0 0,21,172:7:0 +17 792 . T 0 . DP=26;I16=11,15,0,0,895,32009,0,0,1498,88082,0,0,511,11833,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,184:7:0 0,21,172:7:0 +17 793 . G 0 . DP=27;I16=11,15,0,0,965,36389,0,0,1498,88082,0,0,504,11652,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,193:7:0 0,21,170:7:0 +17 794 . G 0 . DP=26;I16=11,15,0,0,888,31804,0,0,1498,88082,0,0,508,11592,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,198:8:0 0,18,161:6:0 +17 795 . T 0 . DP=26;I16=9,15,0,0,859,31399,0,0,1409,83641,0,0,472,10908,0,0;QS=3,0;MQSB=0.96464;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,211:7:0 0,18,160:6:0 +17 796 . T 0 . DP=27;I16=11,16,0,0,907,31641,0,0,1558,91682,0,0,499,11375,0,0;QS=3,0;MQSB=0.992419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,221:9:0 0,15,150:5:0 +17 797 . G 0 . DP=26;I16=11,15,0,0,882,31700,0,0,1529,90841,0,0,498,11298,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,215:9:0 0,12,135:4:0 +17 798 . C 0 . DP=26;I16=9,15,0,0,806,28552,0,0,1440,86400,0,0,466,10582,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,207:8:0 0,12,126:4:0 +17 799 . C 0 . DP=26;I16=10,15,0,0,947,36407,0,0,1500,90000,0,0,491,11185,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,234:9:0 0,12,137:4:0 +17 800 . T 0 . DP=26;I16=11,15,0,0,993,38475,0,0,1529,90841,0,0,495,11199,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,255:9:0 0,12,139:4:0 +17 801 . G 0 . DP=25;I16=11,14,0,0,938,35854,0,0,1469,87241,0,0,495,11209,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,240:9:0 0,12,145:4:0 +17 802 . G 0 . DP=25;I16=11,14,0,0,892,32802,0,0,1469,87241,0,0,495,11239,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,229:9:0 0,12,137:4:0 +17 803 . G 0 . DP=25;I16=11,14,0,0,906,33502,0,0,1469,87241,0,0,495,11289,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,237:9:0 0,12,136:4:0 +17 804 . G 0 . DP=25;I16=11,12,0,0,868,33326,0,0,1349,80041,0,0,466,10846,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,223:8:0 0,12,138:4:0 +17 805 . C 0 . DP=24;I16=9,14,0,0,810,29684,0,0,1380,82800,0,0,482,11208,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,220:8:0 0,12,128:4:0 +17 806 . C 0 . DP=25;I16=9,14,0,0,814,29856,0,0,1380,82800,0,0,483,11293,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,214:8:0 0,12,122:4:0 +17 807 . A 0 . DP=25;I16=10,15,0,0,939,35997,0,0,1500,90000,0,0,503,11525,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,242:9:0 0,12,146:4:0 +17 808 . G 0 . DP=25;I16=10,15,0,0,918,34720,0,0,1500,90000,0,0,505,11591,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,238:9:0 0,12,136:4:0 +17 809 . G 0 . DP=25;I16=10,15,0,0,926,34932,0,0,1500,90000,0,0,506,11626,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,226:9:0 0,12,136:4:0 +17 810 . G C, 0 . DP=25;I16=10,13,0,1,824,30436,14,196,1380,82800,60,3600,480,11288,14,196;QS=2.96552,0.0344828,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,21,255,33,255,255:12:1 0,24,216,24,216,216:8:0 0,12,132,12,132,132:4:0 +17 811 . A 0 . DP=25;I16=9,14,0,0,808,29404,0,0,1380,82800,0,0,484,11294,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,204:7:0 0,12,139:4:0 +17 812 . A 0 . DP=25;I16=10,15,0,0,831,29515,0,0,1500,90000,0,0,500,11392,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,216:9:0 0,12,139:4:0 +17 813 . C 0 . DP=25;I16=10,15,0,0,915,34093,0,0,1500,90000,0,0,497,11307,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,239:9:0 0,12,138:4:0 +17 814 . T 0 . DP=25;I16=10,15,0,0,987,39343,0,0,1500,90000,0,0,494,11244,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,255:9:0 0,12,148:4:0 +17 815 . T 0 . DP=25;I16=10,15,0,0,894,32670,0,0,1500,90000,0,0,491,11203,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,235:9:0 0,12,143:4:0 +17 816 . T 0 . DP=25;I16=10,15,0,0,898,32990,0,0,1500,90000,0,0,488,11184,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,239:9:0 0,12,136:4:0 +17 817 . C 0 . DP=24;I16=10,14,0,0,898,34256,0,0,1440,86400,0,0,485,11137,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,235:9:0 0,12,124:4:0 +17 818 . T 0 . DP=23;I16=9,14,0,0,883,34371,0,0,1380,82800,0,0,484,11110,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,225:8:0 0,12,143:4:0 +17 819 . G 0 . DP=23;I16=9,13,0,0,832,31932,0,0,1320,79200,0,0,461,10573,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,217:8:0 0,12,142:4:0 +17 820 . G 0 . DP=24;I16=10,14,0,0,844,30848,0,0,1440,86400,0,0,484,11114,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,230:9:0 0,12,135:4:0 +17 821 . G 0 . DP=24;I16=10,14,0,0,852,31572,0,0,1440,86400,0,0,484,11098,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,234:9:0 0,12,142:4:0 +17 822 . G 0 . DP=25;I16=10,15,0,0,879,31785,0,0,1500,90000,0,0,481,10955,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,220:9:0 0,12,127:4:0 +17 823 . T 0 . DP=25;I16=10,15,0,0,844,29686,0,0,1500,90000,0,0,478,10786,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,217:9:0 0,12,127:4:0 +17 824 . C 0 . DP=25;I16=9,14,0,0,824,30252,0,0,1380,82800,0,0,427,9477,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,215:9:0 0,9,98:3:0 +17 825 . A 0 . DP=25;I16=10,15,0,0,881,31665,0,0,1500,90000,0,0,467,10277,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,234:9:0 0,12,116:4:0 +17 826 . T 0 . DP=25;I16=10,15,0,0,826,28364,0,0,1500,90000,0,0,461,10039,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,250:12:0 0,27,232:9:0 0,12,117:4:0 +17 827 . A 0 . DP=25;I16=10,15,0,0,851,29477,0,0,1500,90000,0,0,455,9829,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,227:9:0 0,12,123:4:0 +17 828 . T C, 0 . DP=25;I16=2,4,8,11,199,6917,656,23340,360,21600,1140,68400,116,2716,333,6931;QS=0.597777,2.40222,0;VDB=0.842082;SGB=-4.20907;RPB=0.950652;MQB=1;MQSB=1;BQB=0.929717;MQ0F=0 PL:DP:DV 211,0,35,217,65,255:12:10 116,0,91,128,106,213:9:5 120,12,0,120,12,120:4:4 +17 829 . T 0 . DP=24;I16=10,13,0,0,863,32931,0,0,1380,82800,0,0,418,8818,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,242:8:0 0,12,132:4:0 +17 830 . C 0 . DP=24;I16=10,14,0,0,910,34966,0,0,1440,86400,0,0,437,9267,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,220:8:0 0,12,134:4:0 +17 831 . T 0 . DP=24;I16=10,14,0,0,906,34886,0,0,1440,86400,0,0,431,9119,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,243:8:0 0,12,133:4:0 +17 832 . C 0 . DP=24;I16=10,14,0,0,888,33634,0,0,1440,86400,0,0,425,8999,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,220:8:0 0,12,123:4:0 +17 833 . T 0 . DP=25;I16=10,14,0,0,820,29920,0,0,1440,86400,0,0,418,8856,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,224:8:0 0,12,113:4:0 +17 834 . G A, 0 . DP=25;I16=2,3,7,10,164,5898,590,21124,300,18000,1020,61200,104,2296,305,6441;QS=0.520056,2.47994,0;VDB=0.788006;SGB=-4.01214;RPB=0.999233;MQB=1;MQSB=1;BQB=0.821668;MQ0F=0 PL:DP:DV 185,0,46,191,73,246:11:9 128,0,59,137,74,193:8:5 89,9,0,89,9,89:3:3 +17 835 . T 0 . DP=26;I16=9,15,0,0,767,26675,0,0,1440,86400,0,0,406,8652,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,240:12:0 0,24,213:8:0 0,12,98:4:0 +17 836 . G 0 . DP=23;I16=8,15,0,0,833,30561,0,0,1380,82800,0,0,403,8541,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,243:11:0 0,24,214:8:0 0,12,130:4:0 +17 837 . T 0 . DP=23;I16=8,15,0,0,843,31499,0,0,1380,82800,0,0,400,8456,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,241:11:0 0,24,221:8:0 0,12,143:4:0 +17 838 . T 0 . DP=23;I16=8,15,0,0,870,33172,0,0,1380,82800,0,0,397,8397,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,252:11:0 0,24,224:8:0 0,12,134:4:0 +17 839 . G 0 . DP=24;I16=8,15,0,0,862,32774,0,0,1380,82800,0,0,393,8315,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,249:11:0 0,24,212:8:0 0,12,142:4:0 +17 840 . A 0 . DP=25;I16=9,15,0,0,876,32682,0,0,1440,86400,0,0,375,7731,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,243:11:0 0,21,196:7:0 0,18,180:6:0 +17 841 . T 0 . DP=25;I16=9,16,0,0,861,30879,0,0,1500,90000,0,0,396,8260,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,213:11:0 0,24,226:8:0 0,18,185:6:0 +17 842 . T 0 . DP=24;I16=9,15,0,0,872,31990,0,0,1440,86400,0,0,393,8199,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,227:10:0 0,24,231:8:0 0,18,175:6:0 +17 843 . C 0 . DP=24;I16=9,15,0,0,844,30604,0,0,1440,86400,0,0,390,8172,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,228:10:0 0,24,229:8:0 0,18,160:6:0 +17 844 . T 0 . DP=24;I16=9,15,0,0,900,34094,0,0,1440,86400,0,0,386,8128,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,227:10:0 0,24,238:8:0 0,18,189:6:0 +17 845 . G 0 . DP=25;I16=10,15,0,0,916,33866,0,0,1500,90000,0,0,382,8116,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,239:10:0 0,24,225:8:0 0,21,196:7:0 +17 846 . G 0 . DP=24;I16=9,14,0,0,802,28414,0,0,1380,82800,0,0,354,7460,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,223:9:0 0,24,208:8:0 0,18,164:6:0 +17 847 . T 0 . DP=24;I16=8,15,0,0,809,29007,0,0,1380,82800,0,0,377,8083,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,210:9:0 0,24,219:8:0 0,18,149:6:0 +17 848 . G 0 . DP=23;I16=8,15,0,0,829,30351,0,0,1380,82800,0,0,384,8138,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,199:8:0 0,27,243:9:0 0,18,167:6:0 +17 849 . G 0 . DP=22;I16=8,12,0,0,684,23844,0,0,1200,72000,0,0,349,7517,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,160:6:0 0,27,233:9:0 0,15,140:5:0 +17 850 . T 0 . DP=21;I16=6,14,0,0,706,25508,0,0,1200,72000,0,0,360,7568,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,153:6:0 0,24,226:8:0 0,18,147:6:0 +17 851 . G 0 . DP=21;I16=7,14,0,0,707,24667,0,0,1260,75600,0,0,386,8254,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,140:6:0 0,27,233:9:0 0,18,156:6:0 +17 852 . G 0 . DP=21;I16=7,13,0,0,687,24223,0,0,1200,72000,0,0,368,7976,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,147:6:0 0,27,222:9:0 0,15,146:5:0 +17 853 . A 0 . DP=21;I16=7,14,0,0,721,25603,0,0,1260,75600,0,0,388,8442,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,146:6:0 0,27,223:9:0 0,18,166:6:0 +17 854 . A 0 . DP=21;I16=7,14,0,0,725,25843,0,0,1260,75600,0,0,389,8517,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,179:7:0 0,24,209:8:0 0,18,168:6:0 +17 855 . A 0 . DP=21;I16=7,14,0,0,683,23803,0,0,1260,75600,0,0,391,8611,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,171:7:0 0,24,204:8:0 0,18,152:6:0 +17 856 . C 0 . DP=21;I16=7,14,0,0,763,28293,0,0,1260,75600,0,0,392,8676,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,192:7:0 0,24,222:8:0 0,18,172:6:0 +17 857 . A 0 . DP=22;I16=8,14,0,0,786,28480,0,0,1320,79200,0,0,393,8763,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,182:7:0 0,24,220:8:0 0,21,194:7:0 +17 858 . A 0 . DP=22;I16=8,14,0,0,816,31358,0,0,1320,79200,0,0,395,8873,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,192:7:0 0,24,236:8:0 0,21,198:7:0 +17 859 . G 0 . DP=22;I16=8,14,0,0,824,31356,0,0,1320,79200,0,0,395,8907,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,202:7:0 0,24,223:8:0 0,21,203:7:0 +17 860 . A 0 . DP=22;I16=8,13,0,0,743,26985,0,0,1260,75600,0,0,369,8291,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,184:7:0 0,21,202:7:0 0,21,190:7:0 +17 861 . C 0 . DP=22;I16=8,14,0,0,770,28376,0,0,1320,79200,0,0,393,8899,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,206:8:0 0,24,216:8:0 0,18,161:6:0 +17 862 . T 0 . DP=22;I16=8,14,0,0,762,27500,0,0,1320,79200,0,0,393,8905,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,188:8:0 0,24,213:8:0 0,18,177:6:0 +17 863 . G 0 . DP=23;I16=9,14,0,0,836,30660,0,0,1380,82800,0,0,393,8935,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,24,221:8:0 0,18,180:6:0 +17 864 . T 0 . DP=22;I16=9,13,0,0,795,29085,0,0,1320,79200,0,0,395,8989,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,215:8:0 0,24,221:8:0 0,18,180:6:0 +17 865 . C 0 . DP=22;I16=8,14,0,0,785,28475,0,0,1320,79200,0,0,397,9015,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,21,193:7:0 0,18,177:6:0 +17 866 . C 0 . DP=21;I16=7,13,0,0,694,24890,0,0,1200,72000,0,0,395,8985,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,220:8:0 0,18,149:6:0 0,18,177:6:0 +17 867 . C 0 . DP=21;I16=7,14,0,0,761,28443,0,0,1260,75600,0,0,403,9023,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,223:9:0 0,18,182:6:0 0,18,187:6:0 +17 868 . A 0 . DP=21;I16=7,14,0,0,799,31183,0,0,1260,75600,0,0,406,9054,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,18,189:6:0 0,18,202:6:0 +17 869 . G 0 . DP=21;I16=7,14,0,0,795,30733,0,0,1260,75600,0,0,409,9103,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,236:9:0 0,18,190:6:0 0,18,187:6:0 +17 870 . C 0 . DP=21;I16=7,13,0,0,758,29080,0,0,1200,72000,0,0,403,9089,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,226:8:0 0,18,183:6:0 0,18,187:6:0 +17 871 . C 0 . DP=21;I16=7,14,0,0,769,29383,0,0,1260,75600,0,0,413,9155,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,232:9:0 0,18,176:6:0 0,18,192:6:0 +17 872 . T 0 . DP=21;I16=7,14,0,0,785,29879,0,0,1260,75600,0,0,413,9109,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,18,187:6:0 0,18,188:6:0 +17 873 . G 0 . DP=21;I16=7,14,0,0,768,28506,0,0,1260,75600,0,0,413,9083,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,18,172:6:0 0,18,182:6:0 +17 874 . G 0 . DP=21;I16=7,12,0,0,700,26434,0,0,1140,68400,0,0,374,8234,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,227:8:0 0,15,143:5:0 0,18,189:6:0 +17 875 . G 0 . DP=21;I16=7,14,0,0,717,25659,0,0,1260,75600,0,0,411,8995,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,18,163:6:0 0,18,159:6:0 +17 876 . T 0 . DP=21;I16=7,14,0,0,719,25261,0,0,1260,75600,0,0,410,8984,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,222:9:0 0,18,156:6:0 0,18,173:6:0 +17 877 . G 0 . DP=21;I16=7,14,0,0,747,27419,0,0,1260,75600,0,0,409,8995,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,235:9:0 0,18,162:6:0 0,18,176:6:0 +17 878 . A 0 . DP=21;I16=7,13,0,0,738,27650,0,0,1200,72000,0,0,391,8739,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,216:8:0 0,18,172:6:0 0,18,191:6:0 +17 879 . T 0 . DP=21;I16=7,13,0,0,731,26927,0,0,1200,72000,0,0,389,8759,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,214:8:0 0,18,175:6:0 0,18,184:6:0 +17 880 . A 0 . DP=21;I16=7,14,0,0,737,26481,0,0,1260,75600,0,0,405,9109,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,18,165:6:0 0,18,172:6:0 +17 881 . C 0 . DP=20;I16=7,13,0,0,742,27898,0,0,1200,72000,0,0,404,9154,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,231:8:0 0,18,164:6:0 0,18,183:6:0 +17 882 . A 0 . DP=20;I16=7,13,0,0,776,30564,0,0,1200,72000,0,0,403,9217,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,225:8:0 0,18,188:6:0 0,18,200:6:0 +17 883 . G 0 . DP=20;I16=7,13,0,0,702,25898,0,0,1200,72000,0,0,401,9247,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,214:8:0 0,18,175:6:0 0,18,176:6:0 +17 884 . C 0 . DP=19;I16=7,12,0,0,629,21449,0,0,1140,68400,0,0,400,9292,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,201:8:0 0,18,155:6:0 0,15,144:5:0 +17 885 . G 0 . DP=18;I16=7,11,0,0,605,20851,0,0,1080,64800,0,0,400,9350,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,215:8:0 0,15,140:5:0 0,15,130:5:0 +17 886 . A 0 . DP=18;I16=7,11,0,0,681,26145,0,0,1080,64800,0,0,400,9420,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,222:8:0 0,15,164:5:0 0,15,163:5:0 +17 887 . G 0 . DP=18;I16=7,11,0,0,631,22891,0,0,1080,64800,0,0,399,9451,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,222:8:0 0,15,138:5:0 0,15,149:5:0 +17 888 . A 0 . DP=18;I16=7,10,0,0,593,21563,0,0,1020,61200,0,0,373,8867,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,216:8:0 0,15,132:5:0 0,12,127:4:0 +17 889 . C 0 . DP=18;I16=7,11,0,0,624,22732,0,0,1080,64800,0,0,396,9492,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,213:8:0 0,15,134:5:0 0,15,160:5:0 +17 890 . C 0 . DP=19;I16=7,11,0,0,616,22426,0,0,1080,64800,0,0,368,8826,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,215:8:0 0,15,138:5:0 0,15,152:5:0 +17 891 . C 0 . DP=19;I16=7,11,0,0,661,24891,0,0,1080,64800,0,0,365,8745,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,227:8:0 0,15,141:5:0 0,15,165:5:0 +17 892 . C 0 . DP=19;I16=7,12,0,0,691,25761,0,0,1140,68400,0,0,387,9299,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,230:9:0 0,15,146:5:0 0,15,167:5:0 +17 893 . A 0 . DP=19;I16=7,12,0,0,673,24521,0,0,1140,68400,0,0,384,9238,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,221:9:0 0,15,142:5:0 0,15,166:5:0 +17 894 . T 0 . DP=19;I16=7,12,0,0,670,24268,0,0,1140,68400,0,0,380,9138,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,225:9:0 0,15,134:5:0 0,15,165:5:0 +17 895 . C 0 . DP=20;I16=8,12,0,0,712,26186,0,0,1200,72000,0,0,376,9050,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,15,149:5:0 0,15,162:5:0 +17 896 . T 0 . DP=19;I16=8,10,0,0,684,26696,0,0,1080,64800,0,0,348,8300,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,12,141:4:0 0,15,180:5:0 +17 897 . C 0 . DP=18;I16=8,10,0,0,693,27001,0,0,1080,64800,0,0,370,8764,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,12,131:4:0 0,15,166:5:0 +17 898 . T 0 . DP=18;I16=8,10,0,0,674,25656,0,0,1080,64800,0,0,367,8617,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,243:9:0 0,12,125:4:0 0,15,172:5:0 +17 899 . A 0 . DP=18;I16=9,8,0,0,597,21451,0,0,1020,61200,0,0,340,7858,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,9,99:3:0 0,15,145:5:0 +17 900 . C 0 . DP=18;I16=9,9,0,0,658,24550,0,0,1080,64800,0,0,364,8362,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,98:3:0 0,15,166:5:0 +17 901 . C 0 . DP=18;I16=9,9,0,0,680,26004,0,0,1080,64800,0,0,363,8255,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,99:3:0 0,15,169:5:0 +17 902 . A 0 . DP=18;I16=9,9,0,0,681,26253,0,0,1080,64800,0,0,362,8162,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,9,115:3:0 0,15,174:5:0 +17 903 . A 0 . DP=18;I16=9,8,0,0,645,24625,0,0,1020,61200,0,0,336,7458,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,250:9:0 0,9,101:3:0 0,15,171:5:0 +17 904 . A 0 . DP=18;I16=9,9,0,0,640,23412,0,0,1080,64800,0,0,359,7969,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,9,85:3:0 0,15,174:5:0 +17 905 . A 0 . DP=18;I16=9,9,0,0,675,25673,0,0,1080,64800,0,0,357,7871,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,103:3:0 0,15,172:5:0 +17 906 . A 0 . DP=18;I16=9,9,0,0,669,25193,0,0,1080,64800,0,0,355,7789,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,102:3:0 0,15,166:5:0 +17 907 . A 0 . DP=18;I16=9,9,0,0,661,24541,0,0,1080,64800,0,0,353,7723,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,94:3:0 0,15,165:5:0 +17 908 . T 0 . DP=18;I16=9,9,0,0,673,25579,0,0,1080,64800,0,0,351,7673,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,83:3:0 0,15,168:5:0 +17 909 . T 0 . DP=18;I16=9,9,0,0,653,23847,0,0,1080,64800,0,0,348,7590,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,95:3:0 0,15,161:5:0 +17 910 . A 0 . DP=18;I16=9,9,0,0,652,23790,0,0,1080,64800,0,0,344,7476,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,9,104:3:0 0,15,162:5:0 +17 911 . A 0 . DP=18;I16=9,9,0,0,688,26440,0,0,1080,64800,0,0,340,7382,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,109:3:0 0,15,168:5:0 +17 912 . A 0 . DP=18;I16=9,9,0,0,691,26705,0,0,1080,64800,0,0,336,7308,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,115:3:0 0,15,173:5:0 +17 913 . A 0 . DP=19;I16=9,10,0,0,692,25762,0,0,1140,68400,0,0,332,7254,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,109:3:0 0,15,171:5:0 +17 914 . A 0 . DP=19;I16=9,10,0,0,712,26966,0,0,1140,68400,0,0,329,7221,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,109:3:0 0,15,164:5:0 +17 915 . T 0 . DP=18;I16=9,9,0,0,638,23228,0,0,1080,64800,0,0,326,7160,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,9,99:3:0 0,15,163:5:0 +17 916 . T 0 . DP=19;I16=9,8,0,0,626,23136,0,0,1020,61200,0,0,296,6396,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,9,103:3:0 0,15,164:5:0 +17 917 . A 0 . DP=19;I16=9,10,0,0,726,27962,0,0,1117,66169,0,0,318,6908,0,0;QS=3,0;MQSB=0.934728;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,125:4:0 0,15,171:5:0 +17 918 . G 0 . DP=19;I16=9,10,0,0,688,25456,0,0,1117,66169,0,0,314,6818,0,0;QS=3,0;MQSB=0.934728;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,129:4:0 0,15,147:5:0 +17 919 . C 0 . DP=18;I16=8,10,0,0,672,25786,0,0,1057,62569,0,0,311,6751,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,92:3:0 0,15,152:5:0 +17 920 . T 0 . DP=18;I16=8,10,0,0,681,26113,0,0,1057,62569,0,0,308,6706,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,95:3:0 0,15,171:5:0 +17 921 . G 0 . DP=17;I16=7,10,0,0,617,22841,0,0,997,58969,0,0,304,6582,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,6,47:2:0 0,15,164:5:0 +17 922 . G 0 . DP=16;I16=7,8,0,0,560,21156,0,0,877,51769,0,0,276,5852,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,24,243:8:0 0,6,64:2:0 0,15,151:5:0 +17 923 . G 0 . DP=16;I16=7,8,0,0,562,21350,0,0,877,51769,0,0,273,5765,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,24,245:8:0 0,6,65:2:0 0,15,144:5:0 +17 924 . C 0 . DP=16;I16=7,9,0,0,603,22955,0,0,937,55369,0,0,295,6321,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,6,57:2:0 0,15,157:5:0 +17 925 . A 0 . DP=16;I16=7,9,0,0,576,21618,0,0,937,55369,0,0,291,6219,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,6,58:2:0 0,15,163:5:0 +17 926 . T 0 . DP=16;I16=7,9,0,0,585,22015,0,0,937,55369,0,0,287,6133,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,6,63:2:0 0,15,161:5:0 +17 927 . G 0 . DP=17;I16=7,10,0,0,641,24481,0,0,997,58969,0,0,283,6063,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,9,82:3:0 0,15,158:5:0 +17 928 . G 0 . DP=17;I16=7,10,0,0,625,23195,0,0,997,58969,0,0,280,6010,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,9,84:3:0 0,15,150:5:0 +17 929 . T 0 . DP=16;I16=7,9,0,0,580,21580,0,0,937,55369,0,0,277,5925,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,27,248:9:0 0,9,79:3:0 0,12,128:4:0 +17 930 . G 0 . DP=16;I16=7,8,0,0,565,21561,0,0,877,51769,0,0,249,5233,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,24,247:8:0 0,9,82:3:0 0,12,127:4:0 +17 931 . G 0 . DP=16;I16=7,9,0,0,553,19935,0,0,937,55369,0,0,271,5809,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,9,80:3:0 0,12,113:4:0 +17 932 . T 0 . DP=16;I16=7,9,0,0,558,20128,0,0,937,55369,0,0,268,5778,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,27,229:9:0 0,9,89:3:0 0,12,122:4:0 +17 933 . G 0 . DP=16;I16=7,8,0,0,558,20926,0,0,877,51769,0,0,239,5091,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,24,241:8:0 0,9,94:3:0 0,12,116:4:0 +17 934 . C 0 . DP=15;I16=7,8,0,0,548,20256,0,0,877,51769,0,0,261,5673,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,9,83:3:0 0,9,99:3:0 +17 935 . A 0 . DP=15;I16=7,8,0,0,534,19780,0,0,846,49010,0,0,259,5647,0,0;QS=3,0;MQSB=0.720273;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,9,86:3:0 0,9,101:3:0 +17 936 . T 0 . DP=15;I16=7,8,0,0,579,22499,0,0,846,49010,0,0,257,5589,0,0;QS=3,0;MQSB=0.720273;MQ0F=0 PL:DP:DV 0,27,252:9:0 0,9,91:3:0 0,9,100:3:0 +17 937 . G 0 . DP=16;I16=8,7,0,0,550,20650,0,0,846,49010,0,0,232,5022,0,0;QS=3,0;MQSB=0.651439;MQ0F=0 PL:DP:DV 0,24,228:8:0 0,9,84:3:0 0,12,115:4:0 +17 938 . C 0 . DP=16;I16=8,7,0,0,553,20669,0,0,846,49010,0,0,231,5001,0,0;QS=3,0;MQSB=0.651439;MQ0F=0 PL:DP:DV 0,24,234:8:0 0,9,77:3:0 0,12,119:4:0 +17 939 . C 0 . DP=16;I16=8,8,0,0,582,22100,0,0,906,52610,0,0,250,5392,0,0;QS=3,0;MQSB=0.702619;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,9,71:3:0 0,12,115:4:0 +17 940 . T 0 . DP=15;I16=8,7,0,0,583,23339,0,0,846,49010,0,0,248,5320,0,0;QS=3,0;MQSB=0.651439;MQ0F=0 PL:DP:DV 0,27,252:9:0 0,6,71:2:0 0,12,124:4:0 +17 941 . G 0 . DP=14;I16=7,7,0,0,501,18707,0,0,786,45410,0,0,246,5216,0,0;QS=3,0;MQSB=0.714506;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,6,59:2:0 0,9,93:3:0 +17 942 . T 0 . DP=14;I16=7,7,0,0,525,19799,0,0,786,45410,0,0,244,5128,0,0;QS=3,0;MQSB=0.714506;MQ0F=0 PL:DP:DV 0,27,237:9:0 0,6,70:2:0 0,9,94:3:0 +17 943 . A 0 . DP=14;I16=7,7,0,0,545,21399,0,0,786,45410,0,0,242,5056,0,0;QS=3,0;MQSB=0.714506;MQ0F=0 PL:DP:DV 0,27,248:9:0 0,6,71:2:0 0,9,93:3:0 +17 944 . G 0 . DP=14;I16=7,7,0,0,529,20143,0,0,786,45410,0,0,240,5000,0,0;QS=3,0;MQSB=0.714506;MQ0F=0 PL:DP:DV 0,27,249:9:0 0,6,65:2:0 0,9,95:3:0 +17 945 . T 0 . DP=14;I16=7,7,0,0,523,19621,0,0,786,45410,0,0,238,4960,0,0;QS=3,0;MQSB=0.714506;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,6,70:2:0 0,9,95:3:0 +17 946 . C 0 . DP=13;I16=6,6,0,0,455,17581,0,0,666,38210,0,0,223,4739,0,0;QS=3,0;MQSB=0.660716;MQ0F=0 PL:DP:DV 0,24,240:8:0 0,6,56:2:0 0,6,70:2:0 +17 947 . C 0 . DP=14;I16=7,7,0,0,509,19007,0,0,755,42651,0,0,238,4928,0,0;QS=3,0;MQSB=0.925999;MQ0F=0 PL:DP:DV 0,27,251:9:0 0,9,83:3:0 0,6,66:2:0 +17 948 . C 0 . DP=14;I16=7,7,0,0,520,20050,0,0,755,42651,0,0,237,4887,0,0;QS=3,0;MQSB=0.925999;MQ0F=0 PL:DP:DV 0,27,254:9:0 0,9,78:3:0 0,6,69:2:0 +17 949 . A 0 . DP=15;I16=7,8,0,0,547,20705,0,0,815,46251,0,0,236,4864,0,0;QS=3,0;MQSB=0.959011;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,9,90:3:0 0,6,72:2:0 +17 950 . G 0 . DP=15;I16=6,8,0,0,563,22871,0,0,786,45410,0,0,231,4835,0,0;QS=3,0;MQSB=0.740818;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,6,71:2:0 0,6,72:2:0 +17 951 . C 0 . DP=16;I16=7,8,0,0,554,21080,0,0,846,49010,0,0,230,4840,0,0;QS=3,0;MQSB=0.720273;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,65:2:0 0,6,73:2:0 +17 952 . T 0 . DP=16;I16=8,8,0,0,595,22565,0,0,875,49851,0,0,237,4913,0,0;QS=3,0;MQSB=0.934676;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,93:3:0 0,6,73:2:0 +17 953 . A 0 . DP=16;I16=8,8,0,0,567,20515,0,0,875,49851,0,0,237,4921,0,0;QS=3,0;MQSB=0.934676;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,91:3:0 0,6,69:2:0 +17 954 . T 0 . DP=15;I16=7,8,0,0,544,20412,0,0,815,46251,0,0,238,4948,0,0;QS=3,0;MQSB=0.959011;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,9,94:3:0 0,6,69:2:0 +17 955 . T 0 . DP=15;I16=7,8,0,0,543,19953,0,0,815,46251,0,0,239,4993,0,0;QS=3,0;MQSB=0.959011;MQ0F=0 PL:DP:DV 0,30,246:10:0 0,9,95:3:0 0,6,68:2:0 +17 956 . C 0 . DP=15;I16=6,8,0,0,543,21255,0,0,786,45410,0,0,229,4935,0,0;QS=3,0;MQSB=0.740818;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,6,62:2:0 0,6,70:2:0 +17 957 . A 0 . DP=15;I16=7,8,0,0,504,17684,0,0,815,46251,0,0,241,5137,0,0;QS=3,0;MQSB=0.959011;MQ0F=0 PL:DP:DV 0,30,240:10:0 0,9,74:3:0 0,6,67:2:0 +17 958 . C 0 . DP=14;I16=6,8,0,0,505,18981,0,0,755,42651,0,0,243,5235,0,0;QS=3,0;MQSB=0.981425;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,9,78:3:0 0,3,39:1:0 +17 959 . A 0 . DP=14;I16=5,8,0,0,519,20885,0,0,726,41810,0,0,231,5153,0,0;QS=3,0;MQSB=0.765017;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,6,72:2:0 0,3,38:1:0 +17 960 . G 0 . DP=15;I16=6,9,0,0,539,19901,0,0,815,46251,0,0,247,5479,0,0;QS=3,0;MQSB=0.99308;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,106:4:0 0,3,41:1:0 +17 961 . T 0 . DP=14;I16=6,8,0,0,523,19835,0,0,755,42651,0,0,250,5574,0,0;QS=3,0;MQSB=0.981425;MQ0F=0 PL:DP:DV 0,27,248:9:0 0,12,114:4:0 0,3,39:1:0 +17 962 . G 0 . DP=14;I16=5,8,0,0,498,19194,0,0,726,41810,0,0,236,5394,0,0;QS=3,0;MQSB=0.765017;MQ0F=0 PL:DP:DV 0,27,253:9:0 0,9,91:3:0 0,3,36:1:0 +17 963 . C 0 . DP=13;I16=5,8,0,0,500,19610,0,0,695,39051,0,0,256,5754,0,0;QS=3,0;MQSB=0.997325;MQ0F=0 PL:DP:DV 0,24,234:8:0 0,12,118:4:0 0,3,40:1:0 +17 964 . T 0 . DP=13;I16=5,8,0,0,512,20430,0,0,695,39051,0,0,259,5835,0,0;QS=3,0;MQSB=0.997325;MQ0F=0 PL:DP:DV 0,24,227:8:0 0,12,128:4:0 0,3,42:1:0 +17 965 . G 0 . DP=13;I16=4,8,0,0,467,18429,0,0,666,38210,0,0,241,5477,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,228:8:0 0,9,93:3:0 0,3,40:1:0 +17 966 . A 0 . DP=13;I16=4,8,0,0,443,16785,0,0,666,38210,0,0,242,5490,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,212:8:0 0,9,95:3:0 0,3,40:1:0 +17 967 . G 0 . DP=13;I16=4,8,0,0,464,18036,0,0,666,38210,0,0,243,5513,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,230:8:0 0,9,91:3:0 0,3,41:1:0 +17 968 . G 0 . DP=13;I16=4,8,0,0,441,16549,0,0,666,38210,0,0,244,5546,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,218:8:0 0,9,87:3:0 0,3,42:1:0 +17 969 . T 0 . DP=13;I16=4,8,0,0,450,16970,0,0,666,38210,0,0,245,5589,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,220:8:0 0,9,98:3:0 0,3,31:1:0 +17 970 . G 0 . DP=13;I16=4,7,0,0,413,15579,0,0,629,36841,0,0,220,4968,0,0;QS=3,0;MQSB=0.924449;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,6,71:2:0 0,3,33:1:0 +17 971 . G 0 . DP=13;I16=4,8,0,0,459,17711,0,0,666,38210,0,0,245,5609,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,223:8:0 0,9,93:3:0 0,3,38:1:0 +17 972 . G 0 . DP=13;I16=4,8,0,0,446,17192,0,0,666,38210,0,0,245,5637,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,210:8:0 0,9,96:3:0 0,3,39:1:0 +17 973 . A 0 . DP=12;I16=4,7,0,0,402,15018,0,0,606,34610,0,0,246,5676,0,0;QS=3,0;MQSB=0.763675;MQ0F=0 PL:DP:DV 0,21,192:7:0 0,9,89:3:0 0,3,42:1:0 +17 974 . A 0 . DP=12;I16=4,7,0,0,417,16273,0,0,606,34610,0,0,247,5725,0,0;QS=3,0;MQSB=0.763675;MQ0F=0 PL:DP:DV 0,21,198:7:0 0,9,96:3:0 0,3,42:1:0 +17 975 . G 0 . DP=13;I16=4,8,0,0,454,17560,0,0,666,38210,0,0,247,5733,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,213:8:0 0,9,95:3:0 0,3,42:1:0 +17 976 . A 0 . DP=13;I16=4,8,0,0,431,16083,0,0,666,38210,0,0,248,5750,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,227:8:0 0,9,70:3:0 0,3,41:1:0 +17 977 . T 0 . DP=13;I16=4,8,0,0,438,16316,0,0,666,38210,0,0,248,5726,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,210:8:0 0,9,93:3:0 0,3,37:1:0 +17 978 . G 0 . DP=12;I16=4,8,0,0,430,16060,0,0,666,38210,0,0,248,5710,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,224:8:0 0,9,75:3:0 0,3,40:1:0 +17 979 . C 0 . DP=13;I16=4,8,0,0,453,17461,0,0,689,40441,0,0,223,5077,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,27,232:9:0 0,6,72:2:0 0,3,41:1:0 +17 980 . T 0 . DP=13;I16=4,8,0,0,438,16412,0,0,689,40441,0,0,224,5078,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,27,220:9:0 0,6,76:2:0 0,3,43:1:0 +17 981 . T 0 . DP=13;I16=4,9,0,0,484,18602,0,0,726,41810,0,0,250,5714,0,0;QS=3,0;MQSB=0.826565;MQ0F=0 PL:DP:DV 0,27,224:9:0 0,9,97:3:0 0,3,41:1:0 +17 982 . G 0 . DP=14;I16=4,10,0,0,520,20128,0,0,786,45410,0,0,250,5686,0,0;QS=3,0;MQSB=0.852144;MQ0F=0 PL:DP:DV 0,30,237:10:0 0,9,99:3:0 0,3,40:1:0 +17 983 . A 0 . DP=14;I16=4,10,0,0,570,23360,0,0,786,45410,0,0,251,5671,0,0;QS=3,0;MQSB=0.852144;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,101:3:0 0,3,42:1:0 +17 984 . G 0 . DP=15;I16=4,10,0,0,529,20459,0,0,786,45410,0,0,252,5670,0,0;QS=3,0;MQSB=0.852144;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,9,88:3:0 0,3,43:1:0 +17 985 . C 0 . DP=17;I16=4,13,0,0,580,20280,0,0,966,56210,0,0,261,5747,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,33,246:11:0 0,12,100:4:0 0,6,65:2:0 +17 986 . C A, 0 . DP=17;I16=3,12,0,1,519,18353,13,169,846,49010,60,3600,235,5101,4,16;QS=2.95873,0.0412698,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.921781;BQB=1;MQ0F=0 PL:DP:DV 0,16,197,27,200,201:10:1 0,12,108,12,108,108:4:0 0,6,69,6,69,69:2:0 +17 987 . C 0 . DP=17;I16=4,13,0,0,634,23914,0,0,966,56210,0,0,267,5755,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,107:4:0 0,6,69:2:0 +17 988 . A 0 . DP=17;I16=4,13,0,0,633,24341,0,0,966,56210,0,0,269,5737,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,111:4:0 0,6,82:2:0 +17 989 . G 0 . DP=17;I16=4,13,0,0,635,24149,0,0,966,56210,0,0,271,5739,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,114:4:0 0,6,80:2:0 +17 990 . G 0 . DP=16;I16=4,12,0,0,591,22177,0,0,906,52610,0,0,274,5760,0,0;QS=3,0;MQSB=0.88901;MQ0F=0 PL:DP:DV 0,30,246:10:0 0,12,105:4:0 0,6,83:2:0 +17 991 . A 0 . DP=16;I16=3,11,0,0,548,21542,0,0,809,47641,0,0,227,4549,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,27,232:9:0 0,9,100:3:0 0,6,80:2:0 +17 992 . G 0 . DP=16;I16=4,12,0,0,562,20436,0,0,906,52610,0,0,278,5760,0,0;QS=3,0;MQSB=0.88901;MQ0F=0 PL:DP:DV 0,30,240:10:0 0,12,102:4:0 0,6,76:2:0 +17 993 . T 0 . DP=16;I16=4,12,0,0,564,20752,0,0,906,52610,0,0,280,5790,0,0;QS=3,0;MQSB=0.88901;MQ0F=0 PL:DP:DV 0,30,222:10:0 0,12,121:4:0 0,6,73:2:0 +17 994 . T 0 . DP=17;I16=5,11,0,0,597,22625,0,0,906,52610,0,0,270,5696,0,0;QS=3,0;MQSB=0.851779;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,12,123:4:0 0,9,103:3:0 +17 995 . C 0 . DP=16;I16=4,11,0,0,588,23228,0,0,846,49010,0,0,273,5741,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,24,216:8:0 0,12,119:4:0 0,9,110:3:0 +17 996 . A 0 . DP=16;I16=4,12,0,0,562,20416,0,0,906,52610,0,0,290,6000,0,0;QS=3,0;MQSB=0.88901;MQ0F=0 PL:DP:DV 0,27,207:9:0 0,12,107:4:0 0,9,113:3:0 +17 997 . A 0 . DP=16;I16=4,12,0,0,600,23520,0,0,906,52610,0,0,294,6110,0,0;QS=3,0;MQSB=0.88901;MQ0F=0 PL:DP:DV 0,27,209:9:0 0,12,123:4:0 0,9,121:3:0 +17 998 . G 0 . DP=17;I16=4,13,0,0,603,22299,0,0,966,56210,0,0,298,6240,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,30,226:10:0 0,12,99:4:0 0,9,115:3:0 +17 999 . G 0 . DP=17;I16=4,12,0,0,575,21519,0,0,906,52610,0,0,302,6390,0,0;QS=3,0;MQSB=0.88901;MQ0F=0 PL:DP:DV 0,27,202:9:0 0,12,118:4:0 0,9,111:3:0 +17 1000 . C 0 . DP=17;I16=4,13,0,0,637,24465,0,0,966,56210,0,0,308,6564,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,30,235:10:0 0,12,118:4:0 0,9,109:3:0 +17 1001 . T 0 . DP=17;I16=4,13,0,0,647,24907,0,0,966,56210,0,0,312,6708,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,30,228:10:0 0,12,120:4:0 0,9,122:3:0 +17 1002 . G 0 . DP=17;I16=4,13,0,0,627,23691,0,0,966,56210,0,0,316,6872,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,30,220:10:0 0,12,123:4:0 0,9,109:3:0 +17 1003 . C T, 0 . DP=18;I16=4,13,0,1,633,23953,22,484,966,56210,60,3600,297,6515,21,441;QS=2.9375,0.0625,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.913725;BQB=1;MQ0F=0 PL:DP:DV 0,8,207,27,211,220:10:1 0,15,132,15,132,132:5:0 0,9,102,9,102,102:3:0 +17 1004 . A 0 . DP=19;I16=5,14,0,0,653,23107,0,0,1086,63410,0,0,321,7061,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,231:11:0 0,15,131:5:0 0,9,98:3:0 +17 1005 . A 0 . DP=19;I16=5,14,0,0,670,24380,0,0,1086,63410,0,0,324,7138,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,231:11:0 0,15,132:5:0 0,9,113:3:0 +17 1006 . T 0 . DP=19;I16=4,14,0,0,659,24869,0,0,1026,59810,0,0,327,7237,0,0;QS=3,0;MQSB=0.913725;MQ0F=0 PL:DP:DV 0,30,220:10:0 0,15,134:5:0 0,9,115:3:0 +17 1007 . G 0 . DP=18;I16=4,13,0,0,651,25373,0,0,966,56210,0,0,306,6732,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,27,225:9:0 0,15,138:5:0 0,9,113:3:0 +17 1008 . A 0 . DP=18;I16=4,13,0,0,667,27041,0,0,966,56210,0,0,309,6821,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,27,222:9:0 0,15,147:5:0 0,9,118:3:0 +17 1009 . G 0 . DP=18;I16=4,13,0,0,635,24431,0,0,966,56210,0,0,312,6928,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,27,213:9:0 0,15,139:5:0 0,9,116:3:0 +17 1010 . C 0 . DP=18;I16=4,14,0,0,661,25289,0,0,1026,59810,0,0,339,7629,0,0;QS=3,0;MQSB=0.913725;MQ0F=0 PL:DP:DV 0,30,234:10:0 0,15,126:5:0 0,9,114:3:0 +17 1011 . T 0 . DP=18;I16=4,14,0,0,671,25325,0,0,1026,59810,0,0,339,7623,0,0;QS=3,0;MQSB=0.913725;MQ0F=0 PL:DP:DV 0,30,226:10:0 0,15,131:5:0 0,9,118:3:0 +17 1012 . A 0 . DP=19;I16=5,14,0,0,639,22891,0,0,1063,61179,0,0,339,7633,0,0;QS=3,0;MQSB=0.990403;MQ0F=0 PL:DP:DV 0,30,201:10:0 0,18,154:6:0 0,9,113:3:0 +17 1013 . T 0 . DP=18;I16=5,12,0,0,623,23913,0,0,943,53979,0,0,325,7385,0,0;QS=3,0;MQSB=0.998612;MQ0F=0 PL:DP:DV 0,24,202:8:0 0,18,161:6:0 0,9,115:3:0 +17 1014 . G 0 . DP=18;I16=5,13,0,0,656,24596,0,0,1003,57579,0,0,341,7605,0,0;QS=3,0;MQSB=0.995153;MQ0F=0 PL:DP:DV 0,27,218:9:0 0,18,159:6:0 0,9,113:3:0 +17 1015 . A 0 . DP=18;I16=5,13,0,0,646,23878,0,0,1003,57579,0,0,342,7618,0,0;QS=3,0;MQSB=0.995153;MQ0F=0 PL:DP:DV 0,27,209:9:0 0,18,164:6:0 0,9,109:3:0 +17 1016 . T 0 . DP=17;I16=4,12,0,0,588,22114,0,0,929,54841,0,0,340,7632,0,0;QS=3,0;MQSB=0.971017;MQ0F=0 PL:DP:DV 0,27,212:9:0 0,12,124:4:0 0,9,101:3:0 +17 1017 . T 0 . DP=18;I16=5,13,0,0,635,23433,0,0,1026,59810,0,0,346,7694,0,0;QS=3,0;MQSB=0.942222;MQ0F=0 PL:DP:DV 0,27,213:9:0 0,18,155:6:0 0,9,105:3:0 +17 1018 . G 0 . DP=18;I16=5,13,0,0,650,24550,0,0,1026,59810,0,0,349,7757,0,0;QS=3,0;MQSB=0.942222;MQ0F=0 PL:DP:DV 0,27,215:9:0 0,18,179:6:0 0,9,91:3:0 +17 1019 . C 0 . DP=18;I16=5,12,0,0,555,18561,0,0,966,56210,0,0,327,7213,0,0;QS=3,0;MQSB=0.951229;MQ0F=0 PL:DP:DV 0,24,181:8:0 0,18,143:6:0 0,9,104:3:0 +17 1020 . G 0 . DP=19;I16=6,12,0,0,625,22287,0,0,1026,59810,0,0,332,7402,0,0;QS=3,0;MQSB=0.97296;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,18,157:6:0 0,9,87:3:0 +17 1021 . C 0 . DP=19;I16=5,13,0,0,625,22761,0,0,1026,59810,0,0,332,7326,0,0;QS=3,0;MQSB=0.942222;MQ0F=0 PL:DP:DV 0,27,220:9:0 0,18,153:6:0 0,9,92:3:0 +17 1022 . C 0 . DP=19;I16=6,13,0,0,727,27975,0,0,1086,63410,0,0,360,8034,0,0;QS=3,0;MQSB=0.965977;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,168:6:0 0,9,110:3:0 +17 1023 . A 0 . DP=19;I16=6,12,0,0,647,23997,0,0,1026,59810,0,0,338,7510,0,0;QS=3,0;MQSB=0.97296;MQ0F=0 PL:DP:DV 0,27,216:9:0 0,18,168:6:0 0,9,112:3:0 +17 1024 . C 0 . DP=20;I16=7,13,0,0,729,27471,0,0,1146,67010,0,0,364,8154,0,0;QS=3,0;MQSB=0.980568;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,169:6:0 0,9,106:3:0 +17 1025 . T 0 . DP=20;I16=7,13,0,0,757,29387,0,0,1146,67010,0,0,366,8192,0,0;QS=3,0;MQSB=0.980568;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,181:6:0 0,9,117:3:0 +17 1026 . G 0 . DP=20;I16=7,13,0,0,747,28435,0,0,1146,67010,0,0,367,8201,0,0;QS=3,0;MQSB=0.980568;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,169:6:0 0,9,113:3:0 +17 1027 . C 0 . DP=20;I16=7,13,0,0,720,26688,0,0,1146,67010,0,0,368,8232,0,0;QS=3,0;MQSB=0.980568;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,145:6:0 0,9,110:3:0 +17 1028 . A 0 . DP=19;I16=6,12,0,0,645,23681,0,0,1026,59810,0,0,348,7800,0,0;QS=3,0;MQSB=0.97296;MQ0F=0 PL:DP:DV 0,30,238:10:0 0,15,146:5:0 0,9,99:3:0 +17 1029 . C 0 . DP=19;I16=7,12,0,0,699,26817,0,0,1086,63410,0,0,371,8305,0,0;QS=3,0;MQSB=0.985816;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,138:5:0 0,9,111:3:0 +17 1030 . T 0 . DP=19;I16=7,12,0,0,749,29789,0,0,1086,63410,0,0,371,8293,0,0;QS=3,0;MQSB=0.985816;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,158:5:0 0,9,122:3:0 +17 1031 . T 0 . DP=21;I16=9,12,0,0,748,27726,0,0,1206,70610,0,0,371,8297,0,0;QS=3,0;MQSB=0.997478;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,144:5:0 0,9,113:3:0 +17 1032 . T 0 . DP=21;I16=9,12,0,0,761,28033,0,0,1206,70610,0,0,373,8319,0,0;QS=3,0;MQSB=0.997478;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,156:5:0 0,9,111:3:0 +17 1033 . G 0 . DP=22;I16=10,12,0,0,773,28227,0,0,1266,74210,0,0,375,8361,0,0;QS=3,0;MQSB=0.999457;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,169:6:0 0,9,101:3:0 +17 1034 . G 0 . DP=22;I16=8,12,0,0,703,25617,0,0,1169,69241,0,0,340,7684,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,149:5:0 0,9,102:3:0 +17 1035 . C 0 . DP=21;I16=10,11,0,0,719,26103,0,0,1237,73369,0,0,382,8508,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,163:6:0 0,9,94:3:0 +17 1036 . C 0 . DP=22;I16=11,10,0,0,756,28390,0,0,1237,73369,0,0,360,7938,0,0;QS=3,0;MQSB=0.939898;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,175:6:0 0,12,135:4:0 +17 1037 . T 0 . DP=22;I16=11,11,0,0,839,32737,0,0,1297,76969,0,0,389,8641,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,188:6:0 0,12,138:4:0 +17 1038 . G 0 . DP=21;I16=10,10,0,0,752,28750,0,0,1177,69769,0,0,368,8066,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,184:6:0 0,9,107:3:0 +17 1039 . G 0 . DP=21;I16=10,11,0,0,775,29373,0,0,1237,73369,0,0,397,8761,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,189:6:0 0,9,111:3:0 +17 1040 . A 0 . DP=21;I16=10,11,0,0,759,28007,0,0,1237,73369,0,0,401,8851,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,177:6:0 0,9,107:3:0 +17 1041 . C 0 . DP=21;I16=8,11,0,0,713,27117,0,0,1140,68400,0,0,371,8255,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,155:5:0 0,9,110:3:0 +17 1042 . A 0 . DP=23;I16=12,10,0,0,800,29464,0,0,1297,76969,0,0,384,8466,0,0;QS=3,0;MQSB=0.947103;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,185:6:0 0,15,145:5:0 +17 1043 . A 0 . DP=23;I16=12,11,0,0,850,32160,0,0,1357,80569,0,0,414,9192,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,188:6:0 0,15,159:5:0 +17 1044 . C 0 . DP=23;I16=12,10,0,0,812,30758,0,0,1297,76969,0,0,394,8690,0,0;QS=3,0;MQSB=0.947103;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,181:6:0 0,15,150:5:0 +17 1045 . A 0 . DP=23;I16=12,11,0,0,887,34519,0,0,1357,80569,0,0,424,9460,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,197:6:0 0,15,156:5:0 +17 1046 . G 0 . DP=23;I16=12,11,0,0,862,33240,0,0,1357,80569,0,0,428,9576,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,183:6:0 0,15,158:5:0 +17 1047 . A 0 . DP=23;I16=12,11,0,0,890,34804,0,0,1357,80569,0,0,432,9712,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,198:6:0 0,15,165:5:0 +17 1048 . G 0 . DP=23;I16=12,10,0,0,846,33054,0,0,1297,76969,0,0,411,9243,0,0;QS=3,0;MQSB=0.947103;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,195:6:0 0,15,156:5:0 +17 1049 . C 0 . DP=22;I16=12,10,0,0,808,30644,0,0,1297,76969,0,0,441,10043,0,0;QS=3,0;MQSB=0.947103;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,182:6:0 0,15,160:5:0 +17 1050 . A 0 . DP=22;I16=11,10,0,0,808,31334,0,0,1237,73369,0,0,430,9940,0,0;QS=3,0;MQSB=0.939898;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,193:6:0 0,12,138:4:0 +17 1051 . A 0 . DP=21;I16=11,9,0,0,731,27495,0,0,1177,69769,0,0,423,9621,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,18,187:6:0 0,15,150:5:0 +17 1052 . A 0 . DP=21;I16=11,9,0,0,759,29327,0,0,1177,69769,0,0,427,9747,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,27,247:9:0 0,18,190:6:0 0,15,150:5:0 +17 1053 . A 0 . DP=21;I16=11,8,0,0,674,25210,0,0,1117,66169,0,0,406,9264,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,24,224:8:0 0,18,161:6:0 0,15,149:5:0 +17 1054 . C 0 . DP=21;I16=11,10,0,0,791,30157,0,0,1237,73369,0,0,459,10623,0,0;QS=3,0;MQSB=0.939898;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,189:6:0 0,15,153:5:0 +17 1055 . C 0 . DP=22;I16=12,10,0,0,818,31448,0,0,1297,76969,0,0,462,10750,0,0;QS=3,0;MQSB=0.947103;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,191:6:0 0,15,157:5:0 +17 1056 . C 0 . DP=22;I16=12,9,0,0,793,31265,0,0,1237,73369,0,0,441,10271,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,195:6:0 0,15,161:5:0 +17 1057 . T 0 . DP=23;I16=12,10,0,0,821,31667,0,0,1297,76969,0,0,467,10911,0,0;QS=3,0;MQSB=0.947103;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,196:6:0 0,15,159:5:0 +17 1058 . G 0 . DP=23;I16=12,11,0,0,863,32871,0,0,1357,80569,0,0,493,11569,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,197:7:0 0,15,155:5:0 +17 1059 . T 0 . DP=23;I16=12,10,0,0,797,29803,0,0,1297,76969,0,0,468,10944,0,0;QS=3,0;MQSB=0.947103;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,21,202:7:0 0,15,152:5:0 +17 1060 . C 0 . DP=23;I16=12,11,0,0,829,31041,0,0,1357,80569,0,0,492,11536,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,178:7:0 0,15,163:5:0 +17 1061 . T 0 . DP=22;I16=12,9,0,0,810,31840,0,0,1237,73369,0,0,465,10797,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,175:5:0 0,15,158:5:0 +17 1062 . C A, 0 . DP=22;I16=12,9,0,1,826,32780,33,1089,1237,73369,60,3600,462,10652,25,625;QS=2.85398,0.146018,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.947103;BQB=1;MQ0F=0 PL:DP:DV 0,33,255,33,255,255:11:0 15,0,151,30,154,176:6:1 0,15,164,15,164,164:5:0 +17 1063 . T 0 . DP=22;I16=12,9,0,0,820,32460,0,0,1237,73369,0,0,459,10525,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,183:6:0 0,15,166:5:0 +17 1064 . A 0 . DP=23;I16=12,9,0,0,793,30355,0,0,1237,73369,0,0,464,10752,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,180:6:0 0,15,162:5:0 +17 1065 . A 0 . DP=23;I16=12,9,0,0,814,31978,0,0,1237,73369,0,0,462,10694,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,186:6:0 0,15,174:5:0 +17 1066 . A 0 . DP=27;I16=15,9,0,0,890,34378,0,0,1417,84169,0,0,460,10652,0,0;QS=3,0;MQSB=0.96464;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,198:7:0 0,18,181:6:0 +17 1067 . A 0 . DP=27;I16=15,10,0,0,913,35031,0,0,1477,87769,0,0,470,10600,0,0;QS=3,0;MQSB=0.962269;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,208:7:0 0,18,182:6:0 +17 1068 . A 0 . DP=27;I16=15,9,0,0,898,34580,0,0,1417,84169,0,0,456,10342,0,0;QS=3,0;MQSB=0.96464;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,24,218:8:0 0,18,181:6:0 +17 1069 . A 0 . DP=28;I16=16,10,0,0,914,33888,0,0,1537,91369,0,0,481,10925,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,207:8:0 0,21,177:7:0 +17 1070 . A 0 . DP=28;I16=15,11,0,0,955,36445,0,0,1537,91369,0,0,467,10351,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,223:8:0 0,21,188:7:0 +17 1071 . G 0 . DP=28;I16=16,10,0,0,974,37570,0,0,1537,91369,0,0,466,10284,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,192:7:0 0,21,191:7:0 +17 1072 . A 0 . DP=28;I16=16,11,0,0,1007,38205,0,0,1597,94969,0,0,490,10868,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,239:8:0 0,21,195:7:0 +17 1073 . A 0 . DP=28;I16=16,10,0,0,976,37822,0,0,1537,91369,0,0,463,10177,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,24,236:8:0 0,21,199:7:0 +17 1074 . A 0 . DP=28;I16=16,11,0,0,1003,38097,0,0,1597,94969,0,0,484,10664,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,232:8:0 0,21,203:7:0 +17 1075 . A 0 . DP=28;I16=16,10,0,0,964,36762,0,0,1537,91369,0,0,476,10564,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,222:8:0 0,21,200:7:0 +17 1076 . G 0 . DP=28;I16=16,10,0,0,966,37048,0,0,1537,91369,0,0,476,10536,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,209:8:0 0,21,183:7:0 +17 1077 . A 0 . DP=29;I16=17,11,0,0,1038,39240,0,0,1657,98569,0,0,480,10548,0,0;QS=3,0;MQSB=0.967085;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,231:8:0 0,24,209:8:0 +17 1078 . A 0 . DP=29;I16=17,11,0,0,1053,40425,0,0,1657,98569,0,0,480,10562,0,0;QS=3,0;MQSB=0.967085;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,234:8:0 0,24,214:8:0 +17 1079 . A 0 . DP=28;I16=17,10,0,0,1019,39007,0,0,1597,94969,0,0,479,10505,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,223:8:0 0,24,206:8:0 +17 1080 . A 0 . DP=29;I16=18,10,0,0,1049,40827,0,0,1657,98569,0,0,478,10478,0,0;QS=3,0;MQSB=0.971673;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,246:9:0 0,24,218:8:0 +17 1081 . G 0 . DP=30;I16=19,8,0,0,988,37392,0,0,1597,94969,0,0,436,9550,0,0;QS=3,0;MQSB=0.977696;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,210:8:0 0,27,210:9:0 +17 1082 . A 0 . DP=30;I16=20,7,0,0,989,37109,0,0,1597,94969,0,0,438,9564,0,0;QS=3,0;MQSB=0.981425;MQ0F=0 PL:DP:DV 0,27,224:9:0 0,27,226:9:0 0,27,217:9:0 +17 1083 . A 0 . DP=30;I16=20,8,0,0,1039,39827,0,0,1657,98569,0,0,455,9803,0,0;QS=3,0;MQSB=0.979523;MQ0F=0 PL:DP:DV 0,30,246:10:0 0,27,233:9:0 0,27,217:9:0 +17 1084 . A 0 . DP=31;I16=21,8,0,0,1049,39097,0,0,1717,102169,0,0,457,9849,0,0;QS=3,0;MQSB=0.981133;MQ0F=0 PL:DP:DV 0,33,253:11:0 0,27,226:9:0 0,27,215:9:0 +17 1085 . A 0 . DP=30;I16=21,8,0,0,1052,39534,0,0,1717,102169,0,0,486,10552,0,0;QS=3,0;MQSB=0.981133;MQ0F=0 PL:DP:DV 0,30,232:10:0 0,30,247:10:0 0,27,214:9:0 +17 1086 . A 0 . DP=28;I16=21,6,0,0,969,36223,0,0,1597,94969,0,0,492,10660,0,0;QS=3,0;MQSB=0.98481;MQ0F=0 PL:DP:DV 0,30,219:10:0 0,27,236:9:0 0,24,179:8:0 +17 1087 . C 0 . DP=28;I16=22,6,0,0,984,36046,0,0,1657,98569,0,0,498,10796,0,0;QS=3,0;MQSB=0.985992;MQ0F=0 PL:DP:DV 0,30,234:10:0 0,27,229:9:0 0,27,173:9:0 +17 1088 . T 0 . DP=29;I16=23,6,0,0,1133,45203,0,0,1717,102169,0,0,503,10863,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,30,250:10:0 0,27,198:9:0 +17 1089 . C 0 . DP=29;I16=23,6,0,0,1093,42347,0,0,1717,102169,0,0,509,10965,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,30,237:10:0 0,27,188:9:0 +17 1090 . A 0 . DP=29;I16=23,6,0,0,1061,39845,0,0,1717,102169,0,0,515,11103,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,221:10:0 0,30,250:10:0 0,27,183:9:0 +17 1091 . C 0 . DP=29;I16=23,6,0,0,1063,39713,0,0,1717,102169,0,0,521,11277,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,30,244:10:0 0,27,177:9:0 +17 1092 . T 0 . DP=29;I16=23,6,0,0,1121,44489,0,0,1717,102169,0,0,524,11334,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,244:10:0 0,30,251:10:0 0,27,198:9:0 +17 1093 . G 0 . DP=29;I16=23,6,0,0,1085,41377,0,0,1717,102169,0,0,526,11372,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,30,243:10:0 0,27,184:9:0 +17 1094 . G 0 . DP=29;I16=22,6,0,0,1018,38808,0,0,1657,98569,0,0,521,11393,0,0;QS=3,0;MQSB=0.985992;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,30,232:10:0 0,24,185:8:0 +17 1095 . A 0 . DP=28;I16=22,6,0,0,1023,38551,0,0,1657,98569,0,0,529,11443,0,0;QS=3,0;MQSB=0.985992;MQ0F=0 PL:DP:DV 0,30,236:10:0 0,30,244:10:0 0,24,178:8:0 +17 1096 . T 0 . DP=30;I16=24,5,0,0,1020,37168,0,0,1717,102169,0,0,505,10849,0,0;QS=3,0;MQSB=0.989637;MQ0F=0 PL:DP:DV 0,33,234:11:0 0,27,220:9:0 0,27,178:9:0 +17 1097 . A 0 . DP=30;I16=24,6,0,0,1056,38166,0,0,1777,105769,0,0,533,11537,0,0;QS=3,0;MQSB=0.987976;MQ0F=0 PL:DP:DV 0,33,230:11:0 0,30,237:10:0 0,27,177:9:0 +17 1098 . T 0 . DP=29;I16=24,5,0,0,1081,40557,0,0,1717,102169,0,0,537,11633,0,0;QS=3,0;MQSB=0.989637;MQ0F=0 PL:DP:DV 0,30,210:10:0 0,30,251:10:0 0,27,186:9:0 +17 1099 . G 0 . DP=29;I16=24,5,0,0,1091,41719,0,0,1717,102169,0,0,540,11712,0,0;QS=3,0;MQSB=0.989637;MQ0F=0 PL:DP:DV 0,30,229:10:0 0,30,242:10:0 0,27,182:9:0 +17 1100 . A 0 . DP=29;I16=24,5,0,0,1106,42976,0,0,1717,102169,0,0,543,11825,0,0;QS=3,0;MQSB=0.989637;MQ0F=0 PL:DP:DV 0,30,210:10:0 0,30,255:10:0 0,27,191:9:0 +17 1101 . A 0 . DP=29;I16=24,5,0,0,1154,46420,0,0,1717,102169,0,0,545,11921,0,0;QS=3,0;MQSB=0.989637;MQ0F=0 PL:DP:DV 0,30,222:10:0 0,30,255:10:0 0,27,198:9:0 +17 1102 . T 0 . DP=29;I16=24,4,0,0,1046,39520,0,0,1657,98569,0,0,522,11424,0,0;QS=3,0;MQSB=0.991416;MQ0F=0 PL:DP:DV 0,30,210:10:0 0,27,233:9:0 0,27,186:9:0 +17 1103 . G 0 . DP=30;I16=24,6,0,0,1134,43486,0,0,1777,105769,0,0,548,12158,0,0;QS=3,0;MQSB=0.987976;MQ0F=0 PL:DP:DV 0,30,223:10:0 0,30,255:10:0 0,30,222:10:0 +17 1104 . A 0 . DP=28;I16=23,5,0,0,1089,43067,0,0,1657,98569,0,0,552,12296,0,0;QS=3,0;MQSB=0.988819;MQ0F=0 PL:DP:DV 0,27,213:9:0 0,27,233:9:0 0,30,233:10:0 +17 1105 . T 0 . DP=28;I16=23,5,0,0,1035,38743,0,0,1657,98569,0,0,556,12462,0,0;QS=3,0;MQSB=0.988819;MQ0F=0 PL:DP:DV 0,27,203:9:0 0,27,227:9:0 0,30,222:10:0 +17 1106 . A 0 . DP=29;I16=23,5,0,0,1003,36715,0,0,1657,98569,0,0,532,11882,0,0;QS=3,0;MQSB=0.988819;MQ0F=0 PL:DP:DV 0,30,227:10:0 0,24,198:8:0 0,30,217:10:0 +17 1107 . C 0 . DP=29;I16=23,6,0,0,1093,41509,0,0,1717,102169,0,0,558,12532,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,244:10:0 0,27,233:9:0 0,30,220:10:0 +17 1108 . A 0 . DP=29;I16=23,6,0,0,1138,44908,0,0,1717,102169,0,0,558,12536,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,239:10:0 0,27,253:9:0 0,30,227:10:0 +17 1109 . G 0 . DP=29;I16=23,6,0,0,1140,45200,0,0,1717,102169,0,0,557,12519,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,27,240:9:0 0,30,224:10:0 +17 1110 . G 0 . DP=29;I16=23,6,0,0,1086,41054,0,0,1717,102169,0,0,555,12481,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,242:10:0 0,27,229:9:0 0,30,224:10:0 +17 1111 . T 0 . DP=29;I16=22,6,0,0,1025,37919,0,0,1680,100800,0,0,552,12470,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,227:10:0 0,24,227:8:0 0,30,211:10:0 +17 1112 . T 0 . DP=28;I16=22,6,0,0,1034,38986,0,0,1680,100800,0,0,550,12440,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,226:10:0 0,24,221:8:0 0,30,221:10:0 +17 1113 . G 0 . DP=28;I16=23,5,0,0,1085,42273,0,0,1680,100800,0,0,548,12386,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,202:7:0 0,33,222:11:0 +17 1114 . A 0 . DP=28;I16=23,5,0,0,1079,42279,0,0,1680,100800,0,0,546,12306,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,235:10:0 0,21,209:7:0 0,33,238:11:0 +17 1115 . G 0 . DP=28;I16=23,5,0,0,1114,44550,0,0,1680,100800,0,0,544,12250,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,208:7:0 0,33,234:11:0 +17 1116 . G 0 . DP=29;I16=24,5,0,0,1059,39531,0,0,1740,104400,0,0,542,12218,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,236:10:0 0,24,204:8:0 0,33,226:11:0 +17 1117 . A 0 . DP=29;I16=24,5,0,0,1124,43896,0,0,1740,104400,0,0,541,12211,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,235:10:0 0,24,227:8:0 0,33,234:11:0 +17 1118 . T 0 . DP=29;I16=24,4,0,0,1100,44802,0,0,1680,100800,0,0,539,12131,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,230:10:0 0,21,188:7:0 0,33,248:11:0 +17 1119 . C 0 . DP=29;I16=23,4,0,0,1078,44864,0,0,1620,97200,0,0,526,11958,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,224:9:0 0,21,191:7:0 0,33,255:11:0 +17 1120 . C 0 . DP=29;I16=23,5,0,0,1113,46071,0,0,1680,100800,0,0,536,12054,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,24,214:8:0 0,33,255:11:0 +17 1121 . A 0 . DP=30;I16=24,5,0,0,1167,48549,0,0,1740,104400,0,0,536,12056,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,24,220:8:0 0,36,255:12:0 +17 1122 . T 0 . DP=32;I16=26,5,0,0,1235,50967,0,0,1860,111600,0,0,535,11985,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,230:10:0 0,27,238:9:0 0,36,255:12:0 +17 1123 . T 0 . DP=32;I16=26,5,0,0,1219,50121,0,0,1860,111600,0,0,535,11893,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,221:10:0 0,27,236:9:0 0,36,255:12:0 +17 1124 . A 0 . DP=31;I16=25,5,0,0,1187,48827,0,0,1800,108000,0,0,536,11832,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,218:9:0 0,27,235:9:0 0,36,255:12:0 +17 1125 . T 0 . DP=31;I16=25,5,0,0,1211,51001,0,0,1800,108000,0,0,537,11801,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,27,235:9:0 0,36,255:12:0 +17 1126 . C 0 . DP=31;I16=25,5,0,0,1225,52001,0,0,1800,108000,0,0,538,11800,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,234:9:0 0,27,241:9:0 0,36,255:12:0 +17 1127 . T 0 . DP=31;I16=25,5,0,0,1257,55245,0,0,1800,108000,0,0,539,11829,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,231:9:0 0,27,252:9:0 0,36,255:12:0 +17 1128 . G 0 . DP=31;I16=25,5,0,0,1217,51743,0,0,1800,108000,0,0,540,11888,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,236:9:0 0,27,229:9:0 0,36,255:12:0 +17 1129 . A G, 0 . DP=31;I16=24,4,0,1,1101,45631,32,1024,1680,100800,60,3600,514,11300,25,625;QS=2.93535,0.0646465,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,24,204,24,204,204:8:0 0,27,229,27,229,229:9:0 0,4,198,33,201,219:12:1 +17 1130 . A 0 . DP=31;I16=25,5,0,0,1189,49509,0,0,1800,108000,0,0,539,11943,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,215:9:0 0,27,236:9:0 0,36,255:12:0 +17 1131 . A 0 . DP=29;I16=23,5,0,0,1156,49362,0,0,1680,100800,0,0,540,11988,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,206:7:0 0,27,250:9:0 0,36,255:12:0 +17 1132 . T 0 . DP=29;I16=23,5,0,0,1123,47359,0,0,1680,100800,0,0,540,12008,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,198:7:0 0,27,229:9:0 0,36,255:12:0 +17 1133 . G 0 . DP=30;I16=23,5,0,0,1148,48796,0,0,1680,100800,0,0,540,12052,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,214:7:0 0,27,232:9:0 0,36,255:12:0 +17 1134 . C 0 . DP=29;I16=22,6,0,0,1162,50224,0,0,1680,100800,0,0,547,12155,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,209:7:0 0,27,254:9:0 0,36,255:12:0 +17 1135 . T 0 . DP=29;I16=22,6,0,0,1214,55020,0,0,1680,100800,0,0,549,12257,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,209:7:0 0,27,255:9:0 0,36,255:12:0 +17 1136 . T 0 . DP=29;I16=22,6,0,0,1148,49270,0,0,1680,100800,0,0,551,12383,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,200:7:0 0,27,255:9:0 0,36,255:12:0 +17 1137 . G 0 . DP=28;I16=21,6,0,0,1087,46051,0,0,1620,97200,0,0,554,12532,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,214:7:0 0,27,234:9:0 0,33,254:11:0 +17 1138 . G 0 . DP=28;I16=21,6,0,0,1040,42504,0,0,1620,97200,0,0,557,12703,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,197:7:0 0,27,234:9:0 0,33,246:11:0 +17 1139 . A 0 . DP=28;I16=21,6,0,0,1103,47389,0,0,1620,97200,0,0,559,12845,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,200:7:0 0,27,254:9:0 0,33,255:11:0 +17 1140 . C 0 . DP=28;I16=21,6,0,0,1072,44372,0,0,1620,97200,0,0,561,13007,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,214:7:0 0,27,234:9:0 0,33,250:11:0 +17 1141 . C 0 . DP=28;I16=21,6,0,0,1106,47298,0,0,1620,97200,0,0,562,13140,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,212:7:0 0,27,245:9:0 0,33,255:11:0 +17 1142 . A 0 . DP=28;I16=21,6,0,0,1114,47788,0,0,1620,97200,0,0,560,13146,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,212:7:0 0,27,255:9:0 0,33,251:11:0 +17 1143 . G 0 . DP=26;I16=19,7,0,0,1041,42249,0,0,1560,93600,0,0,585,13799,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,222:7:0 0,27,249:9:0 0,30,253:10:0 +17 1144 . A 0 . DP=26;I16=19,7,0,0,1018,40154,0,0,1560,93600,0,0,585,13847,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,205:7:0 0,27,250:9:0 0,30,255:10:0 +17 1145 . T 0 . DP=26;I16=19,7,0,0,1016,39852,0,0,1560,93600,0,0,584,13866,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,206:7:0 0,27,250:9:0 0,30,249:10:0 +17 1146 . G 0 . DP=26;I16=19,7,0,0,1011,39743,0,0,1560,93600,0,0,582,13856,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,210:7:0 0,27,246:9:0 0,30,254:10:0 +17 1147 . T 0 . DP=27;I16=20,6,0,0,1010,39730,0,0,1560,93600,0,0,579,13815,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,207:8:0 0,24,234:8:0 0,30,255:10:0 +17 1148 . T 0 . DP=26;I16=20,6,0,0,1002,39214,0,0,1560,93600,0,0,576,13690,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,196:8:0 0,24,237:8:0 0,30,255:10:0 +17 1149 . T 0 . DP=26;I16=20,6,0,0,1022,40532,0,0,1560,93600,0,0,573,13579,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,205:8:0 0,24,231:8:0 0,30,255:10:0 +17 1150 . T 0 . DP=26;I16=20,6,0,0,1032,41212,0,0,1560,93600,0,0,569,13433,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,208:8:0 0,24,236:8:0 0,30,255:10:0 +17 1151 . G 0 . DP=26;I16=20,6,0,0,1021,40285,0,0,1560,93600,0,0,565,13303,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,220:8:0 0,24,231:8:0 0,30,248:10:0 +17 1152 . A 0 . DP=27;I16=20,7,0,0,1040,40772,0,0,1620,97200,0,0,561,13189,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,202:8:0 0,24,230:8:0 0,33,255:11:0 +17 1153 . A 0 . DP=27;I16=20,7,0,0,1039,40717,0,0,1620,97200,0,0,557,13043,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,202:8:0 0,24,233:8:0 0,33,255:11:0 +17 1154 . T 0 . DP=28;I16=21,7,0,0,1073,41861,0,0,1680,100800,0,0,552,12866,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,212:9:0 0,24,236:8:0 0,33,255:11:0 +17 1155 . T 0 . DP=27;I16=20,7,0,0,1074,43046,0,0,1620,97200,0,0,549,12707,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,211:8:0 0,24,236:8:0 0,33,255:11:0 +17 1156 . T 0 . DP=28;I16=19,8,0,0,1065,42533,0,0,1620,97200,0,0,520,11892,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,210:8:0 0,24,239:8:0 0,33,255:11:0 +17 1157 . T 0 . DP=28;I16=20,8,0,0,1094,43108,0,0,1680,100800,0,0,541,12299,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,230:9:0 0,24,230:8:0 0,33,255:11:0 +17 1158 . G 0 . DP=28;I16=20,8,0,0,1098,43584,0,0,1680,100800,0,0,536,12056,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,24,224:8:0 0,33,255:11:0 +17 1159 . G 0 . DP=28;I16=20,8,0,0,1096,43222,0,0,1680,100800,0,0,530,11790,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,249:9:0 0,24,229:8:0 0,33,255:11:0 +17 1160 . A 0 . DP=30;I16=20,10,0,0,1146,44510,0,0,1800,108000,0,0,524,11552,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,229:9:0 0,24,242:8:0 0,39,255:13:0 +17 1161 . T 0 . DP=30;I16=20,10,0,0,1136,43548,0,0,1800,108000,0,0,520,11344,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,221:9:0 0,24,230:8:0 0,39,255:13:0 +17 1162 . T 0 . DP=30;I16=20,10,0,0,1147,44365,0,0,1800,108000,0,0,516,11168,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,232:9:0 0,24,229:8:0 0,39,255:13:0 +17 1163 . T 0 . DP=31;I16=20,11,0,0,1176,45394,0,0,1860,111600,0,0,511,10975,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,24,231:8:0 0,39,255:13:0 +17 1164 . T 0 . DP=31;I16=20,11,0,0,1166,44864,0,0,1860,111600,0,0,506,10768,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,235:10:0 0,24,234:8:0 0,39,255:13:0 +17 1165 . T 0 . DP=31;I16=20,11,0,0,1189,46635,0,0,1860,111600,0,0,501,10599,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,240:10:0 0,24,231:8:0 0,39,255:13:0 +17 1166 . T 0 . DP=30;I16=19,11,0,0,1137,43791,0,0,1800,108000,0,0,497,10467,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,231:9:0 0,24,228:8:0 0,39,255:13:0 +17 1167 . C 0 . DP=28;I16=17,11,0,0,1114,44588,0,0,1680,100800,0,0,495,10369,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,21,216:7:0 0,36,255:12:0 +17 1168 . A 0 . DP=28;I16=17,11,0,0,1074,41862,0,0,1680,100800,0,0,493,10303,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,21,203:7:0 0,36,255:12:0 +17 1169 . T 0 . DP=28;I16=17,11,0,0,1089,42589,0,0,1680,100800,0,0,491,10269,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,247:9:0 0,21,212:7:0 0,36,255:12:0 +17 1170 . A 0 . DP=27;I16=16,11,0,0,1033,39891,0,0,1620,97200,0,0,490,10266,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,21,214:7:0 0,33,255:11:0 +17 1171 . T 0 . DP=28;I16=17,11,0,0,1086,42472,0,0,1680,100800,0,0,488,10244,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,249:9:0 0,24,223:8:0 0,33,255:11:0 +17 1172 . T 0 . DP=28;I16=17,11,0,0,1086,42598,0,0,1680,100800,0,0,486,10206,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,235:9:0 0,24,228:8:0 0,33,255:11:0 +17 1173 . T 0 . DP=29;I16=18,11,0,0,1126,44348,0,0,1740,104400,0,0,483,10153,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,27,241:9:0 0,33,255:11:0 +17 1174 . T 0 . DP=29;I16=18,11,0,0,1098,42352,0,0,1740,104400,0,0,481,10135,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,230:9:0 0,27,238:9:0 0,33,255:11:0 +17 1175 . G 0 . DP=28;I16=18,10,0,0,1063,40975,0,0,1680,100800,0,0,480,10152,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,234:8:0 0,27,234:9:0 0,33,255:11:0 +17 1176 . T 0 . DP=28;I16=18,10,0,0,1045,39823,0,0,1680,100800,0,0,479,10203,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,27,233:9:0 0,33,255:11:0 +17 1177 . A 0 . DP=28;I16=18,10,0,0,1040,39006,0,0,1680,100800,0,0,478,10288,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,220:8:0 0,27,228:9:0 0,33,255:11:0 +17 1178 . A 0 . DP=27;I16=17,10,0,0,1006,38238,0,0,1620,97200,0,0,477,10355,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,27,227:9:0 0,30,255:10:0 +17 1179 . T 0 . DP=27;I16=17,10,0,0,1012,38396,0,0,1620,97200,0,0,475,10403,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,223:8:0 0,27,224:9:0 0,30,255:10:0 +17 1180 . C 0 . DP=27;I16=16,10,0,0,1006,39508,0,0,1560,93600,0,0,469,10423,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,222:7:0 0,27,224:9:0 0,30,255:10:0 +17 1181 . T 0 . DP=26;I16=16,10,0,0,1021,40581,0,0,1560,93600,0,0,469,10441,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,236:8:0 0,24,229:8:0 0,30,255:10:0 +17 1182 . T 0 . DP=26;I16=14,11,0,0,939,35915,0,0,1500,90000,0,0,457,10347,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,236:9:0 0,21,209:7:0 0,27,255:9:0 +17 1183 . T 0 . DP=25;I16=13,11,0,0,899,34555,0,0,1440,86400,0,0,455,10341,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,18,192:6:0 0,27,255:9:0 +17 1184 . G 0 . DP=24;I16=13,11,0,0,916,35398,0,0,1440,86400,0,0,465,10479,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,234:8:0 0,21,201:7:0 0,27,255:9:0 +17 1185 . C 0 . DP=24;I16=13,11,0,0,908,35014,0,0,1440,86400,0,0,465,10541,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,246:8:0 0,21,191:7:0 0,27,250:9:0 +17 1186 . A 0 . DP=24;I16=13,11,0,0,946,37648,0,0,1440,86400,0,0,463,10525,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,240:8:0 0,21,205:7:0 0,27,255:9:0 +17 1187 . G 0 . DP=25;I16=14,11,0,0,908,33870,0,0,1500,90000,0,0,461,10529,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,21,205:7:0 0,27,240:9:0 +17 1188 . T 0 . DP=25;I16=14,11,0,0,886,32138,0,0,1500,90000,0,0,461,10553,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,21,196:7:0 0,24,216:8:0 +17 1189 . A 0 . DP=25;I16=14,11,0,0,920,34392,0,0,1500,90000,0,0,461,10497,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,174:6:0 0,27,252:9:0 +17 1190 . T 0 . DP=26;I16=14,12,0,0,960,35876,0,0,1560,93600,0,0,462,10462,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,185:6:0 0,27,252:9:0 +17 1191 . A 0 . DP=26;I16=14,12,0,0,928,33922,0,0,1560,93600,0,0,464,10450,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,173:6:0 0,27,245:9:0 +17 1192 . T 0 . DP=26;I16=14,12,0,0,981,37505,0,0,1560,93600,0,0,465,10413,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,191:6:0 0,27,255:9:0 +17 1193 . T 0 . DP=26;I16=14,12,0,0,976,37054,0,0,1560,93600,0,0,466,10402,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,191:6:0 0,27,255:9:0 +17 1194 . T 0 . DP=26;I16=14,12,0,0,951,35219,0,0,1560,93600,0,0,466,10368,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,178:6:0 0,27,249:9:0 +17 1195 . A 0 . DP=26;I16=14,12,0,0,917,33253,0,0,1560,93600,0,0,466,10362,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,177:6:0 0,27,235:9:0 +17 1196 . C 0 . DP=25;I16=13,12,0,0,921,34209,0,0,1500,90000,0,0,466,10334,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,187:6:0 0,27,236:9:0 +17 1197 . C 0 . DP=24;I16=12,12,0,0,906,34862,0,0,1440,86400,0,0,464,10184,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,186:6:0 0,24,233:8:0 +17 1198 . A 0 . DP=24;I16=12,12,0,0,937,36815,0,0,1440,86400,0,0,461,10013,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,190:6:0 0,24,245:8:0 +17 1199 . G 0 . DP=24;I16=12,12,0,0,879,33035,0,0,1440,86400,0,0,457,9821,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,163:6:0 0,24,221:8:0 +17 1200 . T 0 . DP=24;I16=11,12,0,0,895,35141,0,0,1380,82800,0,0,428,9032,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,176:5:0 0,24,247:8:0 +17 1201 . T 0 . DP=24;I16=12,12,0,0,889,33727,0,0,1440,86400,0,0,449,9521,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,177:6:0 0,24,238:8:0 +17 1202 . C 0 . DP=25;I16=13,12,0,0,929,35121,0,0,1500,90000,0,0,445,9413,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,175:6:0 0,24,230:8:0 +17 1203 . A 0 . DP=25;I16=13,12,0,0,943,36107,0,0,1500,90000,0,0,442,9334,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,184:6:0 0,24,241:8:0 +17 1204 . G 0 . DP=24;I16=13,11,0,0,876,33106,0,0,1440,86400,0,0,439,9235,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,174:6:0 0,21,218:7:0 +17 1205 . C 0 . DP=24;I16=13,11,0,0,891,33869,0,0,1440,86400,0,0,436,9166,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,176:6:0 0,21,217:7:0 +17 1206 . A 0 . DP=23;I16=13,10,0,0,846,31744,0,0,1380,82800,0,0,434,9126,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,179:6:0 0,21,212:7:0 +17 1207 . T 0 . DP=23;I16=13,9,0,0,819,30877,0,0,1320,79200,0,0,407,8489,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,254:10:0 0,18,189:6:0 0,18,194:6:0 +17 1208 . C 0 . DP=24;I16=14,10,0,0,910,35236,0,0,1440,86400,0,0,429,9079,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,190:7:0 0,21,217:7:0 +17 1209 . C T, 0 . DP=24;I16=14,9,0,1,869,33481,21,441,1380,82800,60,3600,408,8710,19,361;QS=2.91393,0.0860656,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,30,255,30,255,255:10:0 0,0,153,18,156,166:7:1 0,21,209,21,209,209:7:0 +17 1210 . C 0 . DP=24;I16=14,10,0,0,915,35713,0,0,1440,86400,0,0,425,9091,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,199:7:0 0,21,209:7:0 +17 1211 . T 0 . DP=24;I16=14,10,0,0,905,34669,0,0,1440,86400,0,0,423,9139,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,213:7:0 0,21,214:7:0 +17 1212 . A 0 . DP=24;I16=14,10,0,0,850,30690,0,0,1440,86400,0,0,421,9215,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,246:10:0 0,21,190:7:0 0,21,204:7:0 +17 1213 . A 0 . DP=24;I16=14,10,0,0,852,31192,0,0,1440,86400,0,0,418,9268,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,21,197:7:0 0,21,195:7:0 +17 1214 . C 0 . DP=23;I16=13,10,0,0,851,32099,0,0,1380,82800,0,0,415,9295,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,186:7:0 0,18,184:6:0 +17 1215 . T 0 . DP=23;I16=13,9,0,0,839,32475,0,0,1320,79200,0,0,386,8668,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,211:7:0 0,15,172:5:0 +17 1216 . C 0 . DP=23;I16=13,10,0,0,863,32923,0,0,1380,82800,0,0,406,9260,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,196:7:0 0,18,172:6:0 +17 1217 . A 0 . DP=22;I16=12,10,0,0,820,30926,0,0,1320,79200,0,0,402,9244,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,172:6:0 0,18,191:6:0 +17 1218 . A 0 . DP=22;I16=12,10,0,0,764,27286,0,0,1320,79200,0,0,398,9244,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,145:6:0 0,18,184:6:0 +17 1219 . A 0 . DP=21;I16=12,9,0,0,803,31119,0,0,1260,75600,0,0,395,9259,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,175:6:0 0,15,173:5:0 +17 1220 . A 0 . DP=21;I16=12,9,0,0,752,27700,0,0,1260,75600,0,0,392,9288,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,18,167:6:0 0,15,167:5:0 +17 1221 . A 0 . DP=20;I16=12,8,0,0,722,26564,0,0,1200,72000,0,0,390,9330,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,147:5:0 0,15,157:5:0 +17 1222 . T 0 . DP=18;I16=10,8,0,0,666,25034,0,0,1080,64800,0,0,389,9333,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,245:9:0 0,15,143:5:0 0,12,142:4:0 +17 1223 . T 0 . DP=17;I16=9,7,0,0,574,21262,0,0,960,57600,0,0,364,8720,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,232:9:0 0,12,122:4:0 0,9,120:3:0 +17 1224 . C 0 . DP=19;I16=10,7,0,0,639,24429,0,0,1020,61200,0,0,364,8740,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,128:4:0 0,9,112:3:0 +17 1225 . A 0 . DP=19;I16=10,9,0,0,713,27139,0,0,1109,65641,0,0,395,9419,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,137:5:0 0,12,145:4:0 +17 1226 . A 0 . DP=19;I16=10,9,0,0,688,25468,0,0,1109,65641,0,0,397,9469,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,127:5:0 0,12,147:4:0 +17 1227 . A 0 . DP=19;I16=10,9,0,0,698,26104,0,0,1109,65641,0,0,399,9531,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,133:5:0 0,12,146:4:0 +17 1228 . A 0 . DP=19;I16=10,9,0,0,705,26721,0,0,1109,65641,0,0,399,9505,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,143:5:0 0,12,145:4:0 +17 1229 . A 0 . DP=18;I16=10,8,0,0,693,26891,0,0,1049,62041,0,0,400,9490,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,123:4:0 0,12,138:4:0 +17 1230 . T 0 . DP=18;I16=10,8,0,0,643,23601,0,0,1049,62041,0,0,401,9485,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,30,245:10:0 0,12,115:4:0 0,12,144:4:0 +17 1231 . C 0 . DP=18;I16=10,7,0,0,663,26041,0,0,1020,61200,0,0,390,9320,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,98:3:0 0,12,138:4:0 +17 1232 . T 0 . DP=18;I16=10,8,0,0,683,26261,0,0,1049,62041,0,0,401,9409,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,133:4:0 0,12,129:4:0 +17 1233 . G 0 . DP=18;I16=10,8,0,0,657,24509,0,0,1049,62041,0,0,401,9389,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,124:4:0 0,12,129:4:0 +17 1234 . A 0 . DP=19;I16=10,8,0,0,677,26177,0,0,1080,64800,0,0,386,9134,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,101:3:0 0,12,144:4:0 +17 1235 . A 0 . DP=19;I16=10,9,0,0,697,26363,0,0,1109,65641,0,0,400,9282,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,129:4:0 0,12,140:4:0 +17 1236 . A 0 . DP=19;I16=10,9,0,0,671,24693,0,0,1109,65641,0,0,398,9148,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,103:4:0 0,12,136:4:0 +17 1237 . T 0 . DP=19;I16=9,9,0,0,649,24061,0,0,1049,62041,0,0,370,8356,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,98:3:0 0,12,135:4:0 +17 1238 . C 0 . DP=20;I16=11,9,0,0,733,27709,0,0,1169,69241,0,0,391,8783,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,104:4:0 0,12,145:4:0 +17 1239 . C 0 . DP=20;I16=10,9,0,0,672,24596,0,0,1109,65641,0,0,363,7981,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,76:3:0 0,12,124:4:0 +17 1240 . C 0 . DP=20;I16=11,9,0,0,723,26895,0,0,1169,69241,0,0,385,8451,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,118:4:0 0,12,129:4:0 +17 1241 . A 0 . DP=20;I16=11,9,0,0,719,26575,0,0,1169,69241,0,0,382,8318,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,104:4:0 0,12,141:4:0 +17 1242 . A 0 . DP=21;I16=12,9,0,0,749,27599,0,0,1229,72841,0,0,379,8207,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,109:4:0 0,15,153:5:0 +17 1243 . A 0 . DP=21;I16=12,9,0,0,738,26862,0,0,1229,72841,0,0,377,8119,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,110:4:0 0,15,158:5:0 +17 1244 . C 0 . DP=21;I16=12,8,0,0,670,22952,0,0,1169,69241,0,0,365,7955,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,101:4:0 0,15,148:5:0 +17 1245 . G 0 . DP=21;I16=12,9,0,0,657,21627,0,0,1229,72841,0,0,373,8015,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,245:12:0 0,12,95:4:0 0,15,158:5:0 +17 1246 . C 0 . DP=21;I16=12,9,0,0,652,21348,0,0,1229,72841,0,0,370,7948,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,252:12:0 0,12,95:4:0 0,15,146:5:0 +17 1247 . G 0 . DP=20;I16=11,9,0,0,655,22291,0,0,1169,69241,0,0,367,7853,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,87:4:0 0,15,150:5:0 +17 1248 . C 0 . DP=20;I16=10,8,0,0,659,25037,0,0,1080,64800,0,0,314,6530,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,90:3:0 0,15,156:5:0 +17 1249 . C 0 . DP=21;I16=12,9,0,0,772,28954,0,0,1229,72841,0,0,360,7680,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,111:4:0 0,15,166:5:0 +17 1250 . A 0 . DP=21;I16=12,9,0,0,757,27599,0,0,1229,72841,0,0,356,7554,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,114:4:0 0,15,161:5:0 +17 1251 . A 0 . DP=21;I16=12,9,0,0,758,27890,0,0,1229,72841,0,0,352,7452,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,115:4:0 0,15,174:5:0 +17 1252 . T 0 . DP=21;I16=12,9,0,0,758,27574,0,0,1229,72841,0,0,348,7374,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,124:4:0 0,15,159:5:0 +17 1253 . A 0 . DP=20;I16=12,8,0,0,718,26292,0,0,1169,69241,0,0,345,7319,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,127:4:0 0,12,144:4:0 +17 1254 . A 0 . DP=20;I16=12,8,0,0,781,30817,0,0,1169,69241,0,0,342,7286,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,134:4:0 0,12,156:4:0 +17 1255 . G 0 . DP=21;I16=12,9,0,0,785,30039,0,0,1229,72841,0,0,339,7275,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,128:4:0 0,15,169:5:0 +17 1256 . C 0 . DP=20;I16=12,8,0,0,742,27910,0,0,1169,69241,0,0,338,7286,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,116:4:0 0,15,165:5:0 +17 1257 . A 0 . DP=20;I16=12,8,0,0,745,28017,0,0,1169,69241,0,0,337,7319,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,132:4:0 0,15,167:5:0 +17 1258 . T 0 . DP=20;I16=12,8,0,0,753,28507,0,0,1169,69241,0,0,336,7374,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,126:4:0 0,15,170:5:0 +17 1259 . T 0 . DP=20;I16=12,8,0,0,690,24762,0,0,1169,69241,0,0,335,7451,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,236:11:0 0,12,128:4:0 0,15,170:5:0 +17 1260 . C 0 . DP=20;I16=12,8,0,0,719,26541,0,0,1169,69241,0,0,333,7499,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,127:4:0 0,15,155:5:0 +17 1261 . C 0 . DP=18;I16=11,6,0,0,602,22374,0,0,989,58441,0,0,308,6940,0,0;QS=3,0;MQSB=0.85832;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,117:4:0 0,9,109:3:0 +17 1262 . C 0 . DP=18;I16=12,6,0,0,653,24345,0,0,1049,62041,0,0,333,7597,0,0;QS=3,0;MQSB=0.85394;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,15,145:5:0 0,9,114:3:0 +17 1263 . T 0 . DP=17;I16=12,5,0,0,654,25656,0,0,989,58441,0,0,335,7645,0,0;QS=3,0;MQSB=0.818731;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,15,158:5:0 0,9,118:3:0 +17 1264 . T 0 . DP=17;I16=12,5,0,0,615,22855,0,0,989,58441,0,0,336,7658,0,0;QS=3,0;MQSB=0.818731;MQ0F=0 PL:DP:DV 0,27,226:9:0 0,15,149:5:0 0,9,114:3:0 +17 1265 . T 0 . DP=17;I16=12,5,0,0,620,23176,0,0,989,58441,0,0,334,7538,0,0;QS=3,0;MQSB=0.818731;MQ0F=0 PL:DP:DV 0,27,232:9:0 0,15,144:5:0 0,9,114:3:0 +17 1266 . G 0 . DP=18;I16=13,5,0,0,675,25765,0,0,1049,62041,0,0,332,7438,0,0;QS=3,0;MQSB=0.814433;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,145:5:0 0,9,114:3:0 +17 1267 . A 0 . DP=18;I16=13,5,0,0,663,24799,0,0,1049,62041,0,0,331,7359,0,0;QS=3,0;MQSB=0.814433;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,15,138:5:0 0,9,114:3:0 +17 1268 . G 0 . DP=18;I16=13,5,0,0,638,23584,0,0,1049,62041,0,0,329,7251,0,0;QS=3,0;MQSB=0.814433;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,112:5:0 0,9,108:3:0 +17 1269 . C 0 . DP=18;I16=13,5,0,0,592,20458,0,0,1049,62041,0,0,327,7163,0,0;QS=3,0;MQSB=0.814433;MQ0F=0 PL:DP:DV 0,30,224:10:0 0,15,130:5:0 0,9,107:3:0 +17 1270 . G 0 . DP=18;I16=13,5,0,0,537,16775,0,0,1049,62041,0,0,325,7095,0,0;QS=3,0;MQSB=0.814433;MQ0F=0 PL:DP:DV 0,30,206:10:0 0,15,104:5:0 0,9,98:3:0 +17 1271 . T 0 . DP=18;I16=12,5,0,0,620,22824,0,0,989,58441,0,0,298,6422,0,0;QS=3,0;MQSB=0.818731;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,15,138:5:0 0,9,109:3:0 +17 1272 . C 0 . DP=17;I16=11,5,0,0,597,22587,0,0,929,54841,0,0,297,6393,0,0;QS=3,0;MQSB=0.823561;MQ0F=0 PL:DP:DV 0,27,251:9:0 0,12,113:4:0 0,9,110:3:0 +17 1273 . A 0 . DP=18;I16=12,6,0,0,633,23063,0,0,1049,62041,0,0,318,6866,0,0;QS=3,0;MQSB=0.85394;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,109:4:0 0,9,113:3:0 +17 1274 . T 0 . DP=17;I16=10,6,0,0,609,23335,0,0,929,54841,0,0,293,6205,0,0;QS=3,0;MQSB=0.863243;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,67:2:0 0,9,115:3:0 +17 1275 . G 0 . DP=17;I16=11,6,0,0,602,21976,0,0,989,58441,0,0,317,6763,0,0;QS=3,0;MQSB=0.85832;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,87:3:0 0,9,112:3:0 +17 1276 . T 0 . DP=17;I16=11,6,0,0,587,20925,0,0,989,58441,0,0,316,6714,0,0;QS=3,0;MQSB=0.85832;MQ0F=0 PL:DP:DV 0,33,248:11:0 0,9,94:3:0 0,9,110:3:0 +17 1277 . C 0 . DP=18;I16=11,7,0,0,590,20126,0,0,1049,62041,0,0,314,6634,0,0;QS=3,0;MQSB=0.883327;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,85:3:0 0,9,106:3:0 +17 1278 . G 0 . DP=18;I16=11,7,0,0,603,20675,0,0,1049,62041,0,0,313,6575,0,0;QS=3,0;MQSB=0.883327;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,77:3:0 0,9,96:3:0 +17 1279 . G 0 . DP=18;I16=11,7,0,0,646,23662,0,0,1049,62041,0,0,312,6538,0,0;QS=3,0;MQSB=0.883327;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,85:3:0 0,9,113:3:0 +17 1280 . T 0 . DP=18;I16=10,7,0,0,558,19192,0,0,989,58441,0,0,296,6298,0,0;QS=3,0;MQSB=0.887766;MQ0F=0 PL:DP:DV 0,33,249:11:0 0,9,86:3:0 0,9,97:3:0 +17 1281 . G 0 . DP=17;I16=10,6,0,0,564,21244,0,0,929,54841,0,0,270,5658,0,0;QS=3,0;MQSB=0.863243;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,85:3:0 0,9,103:3:0 +17 1282 . C 0 . DP=18;I16=10,8,0,0,654,24308,0,0,1049,62041,0,0,294,6286,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,94:3:0 0,12,131:4:0 +17 1283 . T 0 . DP=18;I16=10,8,0,0,677,26313,0,0,1049,62041,0,0,294,6308,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,83:3:0 0,12,154:4:0 +17 1284 . T 0 . DP=18;I16=10,8,0,0,631,22949,0,0,1049,62041,0,0,293,6301,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,9,92:3:0 0,12,145:4:0 +17 1285 . G 0 . DP=18;I16=10,7,0,0,657,25545,0,0,989,58441,0,0,267,5691,0,0;QS=3,0;MQSB=0.887766;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,94:3:0 0,12,145:4:0 +17 1286 . G 0 . DP=18;I16=10,8,0,0,650,24684,0,0,1049,62041,0,0,291,6353,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,78:3:0 0,12,148:4:0 +17 1287 . A 0 . DP=17;I16=9,8,0,0,609,22229,0,0,989,58441,0,0,291,6411,0,0;QS=3,0;MQSB=0.91051;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,91:3:0 0,12,137:4:0 +17 1288 . A 0 . DP=17;I16=9,8,0,0,605,22315,0,0,989,58441,0,0,290,6438,0,0;QS=3,0;MQSB=0.91051;MQ0F=0 PL:DP:DV 0,30,245:10:0 0,9,103:3:0 0,12,140:4:0 +17 1289 . T 0 . DP=18;I16=10,8,0,0,637,23207,0,0,1049,62041,0,0,289,6483,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,99:3:0 0,12,141:4:0 +17 1290 . G 0 . DP=15;I16=9,6,0,0,559,21163,0,0,869,51241,0,0,292,6544,0,0;QS=3,0;MQSB=0.868815;MQ0F=0 PL:DP:DV 0,27,242:9:0 0,9,97:3:0 0,9,106:3:0 +17 1291 . T 0 . DP=15;I16=9,6,0,0,547,20303,0,0,869,51241,0,0,295,6619,0,0;QS=3,0;MQSB=0.868815;MQ0F=0 PL:DP:DV 0,27,225:9:0 0,9,91:3:0 0,9,117:3:0 +17 1292 . T 0 . DP=15;I16=9,6,0,0,559,21121,0,0,869,51241,0,0,297,6657,0,0;QS=3,0;MQSB=0.868815;MQ0F=0 PL:DP:DV 0,27,236:9:0 0,9,95:3:0 0,9,113:3:0 +17 1293 . T 0 . DP=15;I16=9,6,0,0,578,22428,0,0,869,51241,0,0,299,6707,0,0;QS=3,0;MQSB=0.868815;MQ0F=0 PL:DP:DV 0,27,242:9:0 0,9,100:3:0 0,9,116:3:0 +17 1294 . G 0 . DP=16;I16=9,7,0,0,606,23572,0,0,929,54841,0,0,301,6769,0,0;QS=3,0;MQSB=0.892753;MQ0F=0 PL:DP:DV 0,27,254:9:0 0,12,110:4:0 0,9,119:3:0 +17 1295 . G 0 . DP=16;I16=9,7,0,0,567,21419,0,0,929,54841,0,0,304,6844,0,0;QS=3,0;MQSB=0.892753;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,12,102:4:0 0,9,114:3:0 +17 1296 . G 0 . DP=16;I16=8,7,0,0,518,19300,0,0,869,51241,0,0,294,6740,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,9,89:3:0 0,9,114:3:0 +17 1297 . G 0 . DP=18;I16=9,8,0,0,551,19323,0,0,958,55682,0,0,322,7444,0,0;QS=3,0;MQSB=0.998843;MQ0F=0 PL:DP:DV 0,30,219:10:0 0,9,86:3:0 0,12,133:4:0 +17 1298 . T 0 . DP=18;I16=10,8,0,0,615,22371,0,0,1018,59282,0,0,336,7638,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,30,233:10:0 0,12,105:4:0 0,12,138:4:0 +17 1299 . T 0 . DP=18;I16=9,8,0,0,619,23135,0,0,958,55682,0,0,328,7548,0,0;QS=3,0;MQSB=0.998843;MQ0F=0 PL:DP:DV 0,30,242:10:0 0,9,97:3:0 0,12,136:4:0 +17 1300 . T 0 . DP=18;I16=10,8,0,0,631,23107,0,0,1018,59282,0,0,338,7638,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,30,235:10:0 0,12,121:4:0 0,12,136:4:0 +17 1301 . T G, 0 . DP=18;I16=8,8,1,0,599,22623,18,324,929,54841,29,841,314,7040,25,625;QS=2.9434,0.0566038,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.998843;BQB=1;MQ0F=0 PL:DP:DV 0,9,213,24,216,222:9:1 0,12,126,12,126,126:4:0 0,12,135,12,135,135:4:0 +17 1302 . G 0 . DP=17;I16=9,8,0,0,624,23544,0,0,958,55682,0,0,341,7709,0,0;QS=3,0;MQSB=0.998843;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,12,127:4:0 0,12,140:4:0 +17 1303 . G 0 . DP=17;I16=9,8,0,0,582,21200,0,0,958,55682,0,0,342,7718,0,0;QS=3,0;MQSB=0.998843;MQ0F=0 PL:DP:DV 0,27,217:9:0 0,12,125:4:0 0,12,138:4:0 +17 1304 . A 0 . DP=18;I16=10,8,0,0,652,24124,0,0,1018,59282,0,0,343,7741,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,27,218:9:0 0,12,131:4:0 0,15,169:5:0 +17 1305 . T 0 . DP=18;I16=10,8,0,0,685,26381,0,0,1018,59282,0,0,345,7779,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,12,122:4:0 0,15,174:5:0 +17 1306 . T 0 . DP=18;I16=9,8,0,0,644,24628,0,0,958,55682,0,0,345,7829,0,0;QS=3,0;MQSB=0.998843;MQ0F=0 PL:DP:DV 0,27,236:9:0 0,9,106:3:0 0,15,168:5:0 +17 1307 . T 0 . DP=17;I16=9,8,0,0,628,23746,0,0,958,55682,0,0,348,7902,0,0;QS=3,0;MQSB=0.998843;MQ0F=0 PL:DP:DV 0,27,226:9:0 0,9,104:3:0 0,15,167:5:0 +17 1308 . A 0 . DP=19;I16=9,10,0,0,690,25500,0,0,1078,62882,0,0,350,7938,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,30,236:10:0 0,12,127:4:0 0,15,173:5:0 +17 1309 . C 0 . DP=19;I16=9,9,0,0,698,27148,0,0,1049,62041,0,0,342,7818,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,106:3:0 0,15,169:5:0 +17 1310 . A 0 . DP=19;I16=9,10,0,0,751,29953,0,0,1078,62882,0,0,356,7958,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,132:4:0 0,15,183:5:0 +17 1311 . G 0 . DP=19;I16=9,10,0,0,742,29384,0,0,1078,62882,0,0,359,7995,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,128:4:0 0,15,174:5:0 +17 1312 . C 0 . DP=19;I16=9,10,0,0,717,27783,0,0,1078,62882,0,0,362,8050,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,115:4:0 0,15,166:5:0 +17 1313 . T 0 . DP=19;I16=9,10,0,0,751,30061,0,0,1078,62882,0,0,364,8074,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,135:4:0 0,15,175:5:0 +17 1314 . T 0 . DP=19;I16=9,10,0,0,707,26983,0,0,1078,62882,0,0,366,8118,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,30,245:10:0 0,12,134:4:0 0,15,174:5:0 +17 1315 . T 0 . DP=19;I16=9,10,0,0,717,27491,0,0,1078,62882,0,0,367,8131,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,12,132:4:0 0,15,174:5:0 +17 1316 . G 0 . DP=21;I16=10,11,0,0,776,29502,0,0,1198,70082,0,0,368,8162,0,0;QS=3,0;MQSB=0.99938;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,128:4:0 0,18,188:6:0 +17 1317 . G 0 . DP=21;I16=10,11,0,0,751,27855,0,0,1198,70082,0,0,371,8213,0,0;QS=3,0;MQSB=0.99938;MQ0F=0 PL:DP:DV 0,33,253:11:0 0,12,130:4:0 0,18,179:6:0 +17 1318 . G 0 . DP=21;I16=10,11,0,0,749,27663,0,0,1198,70082,0,0,372,8188,0,0;QS=3,0;MQSB=0.99938;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,130:4:0 0,18,184:6:0 +17 1319 . A 0 . DP=21;I16=10,11,0,0,768,28390,0,0,1198,70082,0,0,373,8189,0,0;QS=3,0;MQSB=0.99938;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,124:4:0 0,18,186:6:0 +17 1320 . C 0 . DP=21;I16=10,11,0,0,728,25496,0,0,1198,70082,0,0,373,8165,0,0;QS=3,0;MQSB=0.99938;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,113:4:0 0,18,161:6:0 +17 1321 . G 0 . DP=22;I16=10,12,0,0,762,27412,0,0,1289,76441,0,0,374,8164,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,33,244:11:0 0,9,104:3:0 0,24,208:8:0 +17 1322 . C 0 . DP=22;I16=10,12,0,0,852,33528,0,0,1289,76441,0,0,377,8187,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,111:3:0 0,24,225:8:0 +17 1323 . T 0 . DP=22;I16=10,12,0,0,874,35152,0,0,1289,76441,0,0,379,8185,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,112:3:0 0,24,237:8:0 +17 1324 . C 0 . DP=21;I16=9,12,0,0,793,30585,0,0,1229,72841,0,0,381,8157,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,109:3:0 0,24,218:8:0 +17 1325 . A 0 . DP=21;I16=9,12,0,0,782,29430,0,0,1229,72841,0,0,383,8153,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,105:3:0 0,24,218:8:0 +17 1326 . A 0 . DP=21;I16=9,12,0,0,791,30479,0,0,1229,72841,0,0,385,8173,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,9,108:3:0 0,24,230:8:0 +17 1327 . C 0 . DP=23;I16=11,12,0,0,834,31048,0,0,1349,80041,0,0,387,8217,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,99:3:0 0,27,237:9:0 +17 1328 . C 0 . DP=23;I16=11,12,0,0,878,33972,0,0,1349,80041,0,0,391,8287,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,105:3:0 0,27,254:9:0 +17 1329 . T 0 . DP=23;I16=11,12,0,0,882,34756,0,0,1349,80041,0,0,395,8385,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,112:3:0 0,27,255:9:0 +17 1330 . G 0 . DP=23;I16=11,12,0,0,856,32638,0,0,1349,80041,0,0,398,8460,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,101:3:0 0,27,241:9:0 +17 1331 . T 0 . DP=23;I16=11,12,0,0,847,31785,0,0,1349,80041,0,0,400,8512,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,106:3:0 0,27,247:9:0 +17 1332 . A 0 . DP=23;I16=11,12,0,0,826,30264,0,0,1349,80041,0,0,402,8592,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,252:11:0 0,9,104:3:0 0,27,238:9:0 +17 1333 . C 0 . DP=23;I16=11,12,0,0,836,30928,0,0,1349,80041,0,0,404,8700,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,101:3:0 0,27,236:9:0 +17 1334 . C 0 . DP=22;I16=11,11,0,0,830,32380,0,0,1289,76441,0,0,405,8733,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,107:3:0 0,27,238:9:0 +17 1335 . T 0 . DP=22;I16=11,11,0,0,877,35371,0,0,1289,76441,0,0,406,8788,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,113:3:0 0,27,253:9:0 +17 1336 . C 0 . DP=25;I16=12,12,0,0,890,33648,0,0,1378,80882,0,0,398,8784,0,0;QS=3,0;MQSB=0.786628;MQ0F=0 PL:DP:DV 0,33,250:11:0 0,12,131:4:0 0,27,237:9:0 +17 1337 . A 0 . DP=26;I16=13,13,0,0,941,34611,0,0,1498,88082,0,0,411,8967,0,0;QS=3,0;MQSB=0.800737;MQ0F=0 PL:DP:DV 0,33,249:11:0 0,15,152:5:0 0,30,247:10:0 +17 1338 . A 0 . DP=26;I16=12,14,0,0,982,37358,0,0,1498,88082,0,0,416,9048,0,0;QS=3,0;MQSB=0.771623;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,153:5:0 0,30,255:10:0 +17 1339 . T 0 . DP=27;I16=12,15,0,0,989,36855,0,0,1558,91682,0,0,422,9160,0,0;QS=3,0;MQSB=0.765017;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,151:5:0 0,33,255:11:0 +17 1340 . A 0 . DP=27;I16=11,15,0,0,937,34141,0,0,1498,88082,0,0,425,9289,0,0;QS=3,0;MQSB=0.738577;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,15,149:5:0 0,33,254:11:0 +17 1341 . A 0 . DP=27;I16=12,14,0,0,929,33961,0,0,1498,88082,0,0,410,8810,0,0;QS=3,0;MQSB=0.771623;MQ0F=0 PL:DP:DV 0,30,245:10:0 0,15,141:5:0 0,33,255:11:0 +17 1342 . A 0 . DP=27;I16=12,15,0,0,951,34575,0,0,1558,91682,0,0,439,9499,0,0;QS=3,0;MQSB=0.765017;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,15,159:5:0 0,33,249:11:0 +17 1343 . C 0 . DP=25;I16=10,15,0,0,902,33364,0,0,1469,87241,0,0,445,9593,0,0;QS=3,0;MQSB=0.9171;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,140:5:0 0,30,233:10:0 +17 1344 . C 0 . DP=26;I16=10,16,0,0,985,37915,0,0,1529,90841,0,0,451,9715,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,163:6:0 0,30,238:10:0 +17 1345 . T 0 . DP=26;I16=10,16,0,0,1004,39262,0,0,1529,90841,0,0,458,9866,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,182:6:0 0,30,242:10:0 +17 1346 . G 0 . DP=26;I16=10,16,0,0,1003,38983,0,0,1529,90841,0,0,465,10047,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,172:6:0 0,30,239:10:0 +17 1347 . A 0 . DP=26;I16=10,16,0,0,995,38409,0,0,1529,90841,0,0,470,10156,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,177:6:0 0,30,243:10:0 +17 1348 . T 0 . DP=26;I16=10,16,0,0,988,38126,0,0,1529,90841,0,0,474,10242,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,18,185:6:0 0,30,251:10:0 +17 1349 . T 0 . DP=26;I16=9,15,0,0,905,34409,0,0,1409,83641,0,0,454,9730,0,0;QS=3,0;MQSB=0.904837;MQ0F=0 PL:DP:DV 0,24,225:8:0 0,18,176:6:0 0,30,248:10:0 +17 1350 . T 0 . DP=26;I16=10,16,0,0,975,36909,0,0,1498,88082,0,0,485,10495,0,0;QS=3,0;MQSB=0.700784;MQ0F=0 PL:DP:DV 0,27,242:9:0 0,21,195:7:0 0,30,249:10:0 +17 1351 . T 0 . DP=26;I16=10,16,0,0,956,35602,0,0,1498,88082,0,0,491,10663,0,0;QS=3,0;MQSB=0.700784;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,21,193:7:0 0,30,240:10:0 +17 1352 . A 0 . DP=26;I16=10,16,0,0,901,31965,0,0,1498,88082,0,0,496,10810,0,0;QS=3,0;MQSB=0.700784;MQ0F=0 PL:DP:DV 0,27,250:9:0 0,21,180:7:0 0,30,211:10:0 +17 1353 . A 0 . DP=26;I16=10,16,0,0,927,33583,0,0,1498,88082,0,0,499,10885,0,0;QS=3,0;MQSB=0.700784;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,21,187:7:0 0,30,224:10:0 +17 1354 . A 0 . DP=26;I16=10,16,0,0,927,33621,0,0,1498,88082,0,0,502,10986,0,0;QS=3,0;MQSB=0.700784;MQ0F=0 PL:DP:DV 0,27,237:9:0 0,21,190:7:0 0,30,223:10:0 +17 1355 . A 0 . DP=26;I16=10,16,0,0,924,33736,0,0,1498,88082,0,0,505,11113,0,0;QS=3,0;MQSB=0.700784;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,21,186:7:0 0,30,227:10:0 +17 1356 . A 0 . DP=25;I16=10,15,0,0,916,34050,0,0,1438,84482,0,0,509,11265,0,0;QS=3,0;MQSB=0.707404;MQ0F=0 PL:DP:DV 0,27,249:9:0 0,21,178:7:0 0,27,226:9:0 +17 1357 . A 0 . DP=25;I16=9,15,0,0,949,38007,0,0,1378,80882,0,0,488,10816,0,0;QS=3,0;MQSB=0.67032;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,21,193:7:0 0,24,217:8:0 +17 1358 . G 0 . DP=25;I16=9,15,0,0,873,32435,0,0,1378,80882,0,0,491,10967,0,0;QS=3,0;MQSB=0.67032;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,21,172:7:0 0,24,188:8:0 +17 1359 . T 0 . DP=25;I16=9,15,0,0,857,31139,0,0,1378,80882,0,0,494,11144,0,0;QS=3,0;MQSB=0.67032;MQ0F=0 PL:DP:DV 0,27,232:9:0 0,21,184:7:0 0,24,196:8:0 +17 1360 . T 0 . DP=25;I16=9,15,0,0,879,32419,0,0,1378,80882,0,0,497,11347,0,0;QS=3,0;MQSB=0.67032;MQ0F=0 PL:DP:DV 0,27,248:9:0 0,21,184:7:0 0,24,192:8:0 +17 1361 . T 0 . DP=27;I16=9,17,0,0,936,34238,0,0,1498,88082,0,0,500,11576,0,0;QS=3,0;MQSB=0.657209;MQ0F=0 PL:DP:DV 0,27,234:9:0 0,24,201:8:0 0,27,206:9:0 +17 1362 . G 0 . DP=26;I16=9,17,0,0,973,36785,0,0,1498,88082,0,0,502,11680,0,0;QS=3,0;MQSB=0.657209;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,24,202:8:0 0,27,207:9:0 +17 1363 . G 0 . DP=25;I16=8,17,0,0,936,35390,0,0,1438,84482,0,0,504,11756,0,0;QS=3,0;MQSB=0.612391;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,21,181:7:0 0,27,202:9:0 +17 1364 . G 0 . DP=25;I16=8,17,0,0,902,32840,0,0,1438,84482,0,0,504,11752,0,0;QS=3,0;MQSB=0.612391;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,21,184:7:0 0,27,200:9:0 +17 1365 . G 0 . DP=26;I16=9,17,0,0,946,35224,0,0,1498,88082,0,0,503,11717,0,0;QS=3,0;MQSB=0.657209;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,24,190:8:0 0,27,202:9:0 +17 1366 . G 0 . DP=25;I16=8,15,0,0,840,31058,0,0,1318,77282,0,0,454,10450,0,0;QS=3,0;MQSB=0.625784;MQ0F=0 PL:DP:DV 0,21,215:7:0 0,21,181:7:0 0,27,199:9:0 +17 1367 . G C, 0 . DP=25;I16=7,16,0,1,836,30888,27,729,1349,80041,60,3600,472,11152,15,225;QS=2.91641,0.0835913,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.864405;BQB=1;MQ0F=0 PL:DP:DV 0,24,236,24,236,236:8:0 0,21,179,21,179,179:7:0 0,0,171,24,174,189:9:1 +17 1368 . A 0 . DP=26;I16=8,17,0,0,869,30839,0,0,1438,84482,0,0,481,11095,0,0;QS=3,0;MQSB=0.612391;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,21,180:7:0 0,27,197:9:0 +17 1369 . T 0 . DP=26;I16=8,18,0,0,902,32160,0,0,1498,88082,0,0,508,11758,0,0;QS=3,0;MQSB=0.606531;MQ0F=0 PL:DP:DV 0,27,242:9:0 0,24,197:8:0 0,27,194:9:0 +17 1370 . T 0 . DP=27;I16=8,17,0,0,926,34736,0,0,1438,84482,0,0,458,10466,0,0;QS=3,0;MQSB=0.612391;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,21,195:7:0 0,27,215:9:0 +17 1371 . C 0 . DP=27;I16=8,19,0,0,929,33255,0,0,1558,91682,0,0,509,11695,0,0;QS=3,0;MQSB=0.601139;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,24,196:8:0 0,30,196:10:0 +17 1372 . C 0 . DP=27;I16=8,19,0,0,954,34882,0,0,1558,91682,0,0,510,11696,0,0;QS=3,0;MQSB=0.601139;MQ0F=0 PL:DP:DV 0,27,251:9:0 0,24,198:8:0 0,30,200:10:0 +17 1373 . C 0 . DP=26;I16=8,17,0,0,892,32692,0,0,1438,84482,0,0,486,11044,0,0;QS=3,0;MQSB=0.612391;MQ0F=0 PL:DP:DV 0,24,243:8:0 0,21,186:7:0 0,30,195:10:0 +17 1374 . C 0 . DP=26;I16=8,17,0,0,953,36553,0,0,1438,84482,0,0,487,11039,0,0;QS=3,0;MQSB=0.612391;MQ0F=0 PL:DP:DV 0,24,249:8:0 0,21,193:7:0 0,30,211:10:0 +17 1375 . T 0 . DP=27;I16=9,18,0,0,1011,38377,0,0,1558,91682,0,0,512,11630,0,0;QS=3,0;MQSB=0.651439;MQ0F=0 PL:DP:DV 0,27,243:9:0 0,24,215:8:0 0,30,215:10:0 +17 1376 . A 0 . DP=27;I16=9,17,0,0,912,32444,0,0,1498,88082,0,0,488,10992,0,0;QS=3,0;MQSB=0.657209;MQ0F=0 PL:DP:DV 0,27,234:9:0 0,21,198:7:0 0,30,195:10:0 +17 1377 . A 0 . DP=26;I16=9,17,0,0,994,38518,0,0,1498,88082,0,0,515,11625,0,0;QS=3,0;MQSB=0.657209;MQ0F=0 PL:DP:DV 0,24,228:8:0 0,24,221:8:0 0,30,228:10:0 +17 1378 . G 0 . DP=26;I16=9,17,0,0,910,33180,0,0,1498,88082,0,0,517,11653,0,0;QS=3,0;MQSB=0.657209;MQ0F=0 PL:DP:DV 0,24,234:8:0 0,24,199:8:0 0,30,197:10:0 +17 1379 . C 0 . DP=26;I16=9,17,0,0,891,31779,0,0,1498,88082,0,0,519,11701,0,0;QS=3,0;MQSB=0.657209;MQ0F=0 PL:DP:DV 0,24,228:8:0 0,24,198:8:0 0,30,193:10:0 +17 1380 . C 0 . DP=26;I16=9,17,0,0,925,33925,0,0,1498,88082,0,0,520,11720,0,0;QS=3,0;MQSB=0.657209;MQ0F=0 PL:DP:DV 0,24,226:8:0 0,24,202:8:0 0,30,209:10:0 +17 1381 . C 0 . DP=28;I16=10,18,0,0,878,28560,0,0,1618,95282,0,0,521,11761,0,0;QS=3,0;MQSB=0.689069;MQ0F=0 PL:DP:DV 0,24,211:8:0 0,24,177:8:0 0,36,208:12:0 +17 1382 . G 0 . DP=28;I16=8,18,0,0,905,32553,0,0,1529,90841,0,0,482,10912,0,0;QS=3,0;MQSB=0.882497;MQ0F=0 PL:DP:DV 0,24,213:8:0 0,18,152:6:0 0,36,243:12:0 +17 1383 . C 0 . DP=27;I16=10,16,0,0,897,32373,0,0,1498,88082,0,0,502,11242,0,0;QS=3,0;MQSB=0.700784;MQ0F=0 PL:DP:DV 0,24,225:8:0 0,21,163:7:0 0,33,241:11:0 +17 1384 . C 0 . DP=28;I16=11,17,0,0,980,35558,0,0,1618,95282,0,0,529,11885,0,0;QS=3,0;MQSB=0.726331;MQ0F=0 PL:DP:DV 0,27,248:9:0 0,24,184:8:0 0,33,239:11:0 +17 1385 . A 0 . DP=30;I16=11,18,0,0,949,33215,0,0,1678,98882,0,0,508,11356,0,0;QS=3,0;MQSB=0.720887;MQ0F=0 PL:DP:DV 0,30,232:10:0 0,27,185:9:0 0,30,234:10:0 +17 1386 . C 0 . DP=30;I16=11,19,0,0,1088,39938,0,0,1738,102482,0,0,537,12011,0,0;QS=3,0;MQSB=0.715831;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,27,218:9:0 0,33,255:11:0 +17 1387 . C 0 . DP=31;I16=12,19,0,0,1101,40297,0,0,1798,106082,0,0,540,12022,0,0;QS=3,0;MQSB=0.743137;MQ0F=0 PL:DP:DV 0,33,250:11:0 0,27,219:9:0 0,33,252:11:0 +17 1388 . C 0 . DP=31;I16=11,19,0,0,999,34081,0,0,1769,105241,0,0,519,11439,0,0;QS=3,0;MQSB=0.91982;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,185:8:0 0,33,211:11:0 +17 1389 . G 0 . DP=31;I16=11,19,0,0,1065,39119,0,0,1738,102482,0,0,535,11941,0,0;QS=3,0;MQSB=0.715831;MQ0F=0 PL:DP:DV 0,27,234:9:0 0,30,234:10:0 0,33,255:11:0 +17 1390 . G 0 . DP=31;I16=12,19,0,0,1152,43744,0,0,1798,106082,0,0,555,12241,0,0;QS=3,0;MQSB=0.743137;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,30,245:10:0 0,33,255:11:0 +17 1391 . A 0 . DP=31;I16=12,19,0,0,1241,50255,0,0,1798,106082,0,0,560,12326,0,0;QS=3,0;MQSB=0.743137;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,30,255:10:0 0,33,255:11:0 +17 1392 . G 0 . DP=31;I16=12,19,0,0,1160,44364,0,0,1798,106082,0,0,564,12392,0,0;QS=3,0;MQSB=0.743137;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,30,250:10:0 0,33,255:11:0 +17 1393 . A 0 . DP=31;I16=12,19,0,0,1123,41811,0,0,1798,106082,0,0,568,12490,0,0;QS=3,0;MQSB=0.743137;MQ0F=0 PL:DP:DV 0,30,228:10:0 0,30,255:10:0 0,33,255:11:0 +17 1394 . C 0 . DP=31;I16=12,19,0,0,1139,42555,0,0,1798,106082,0,0,571,12569,0,0;QS=3,0;MQSB=0.743137;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,30,244:10:0 0,33,255:11:0 +17 1395 . A 0 . DP=31;I16=12,19,0,0,1206,48048,0,0,1798,106082,0,0,575,12677,0,0;QS=3,0;MQSB=0.743137;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,240:9:0 0,33,255:11:0 +17 1396 . G 0 . DP=31;I16=12,19,0,0,1196,46882,0,0,1798,106082,0,0,579,12763,0,0;QS=3,0;MQSB=0.743137;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,249:9:0 0,33,255:11:0 +17 1397 . C 0 . DP=31;I16=12,18,0,0,993,33339,0,0,1738,102482,0,0,579,12775,0,0;QS=3,0;MQSB=0.748022;MQ0F=0 PL:DP:DV 0,30,231:10:0 0,27,205:9:0 0,33,217:11:0 +17 1398 . G 0 . DP=30;I16=12,18,0,0,1055,38309,0,0,1738,102482,0,0,584,12826,0,0;QS=3,0;MQSB=0.748022;MQ0F=0 PL:DP:DV 0,33,250:11:0 0,27,229:9:0 0,30,244:10:0 +17 1399 . G 0 . DP=30;I16=12,18,0,0,1132,43666,0,0,1738,102482,0,0,586,12854,0,0;QS=3,0;MQSB=0.748022;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,239:9:0 0,30,255:10:0 +17 1400 . A 0 . DP=30;I16=11,18,0,0,1101,42271,0,0,1678,98882,0,0,563,12289,0,0;QS=3,0;MQSB=0.720887;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,27,239:9:0 0,30,246:10:0 +17 1401 . T 0 . DP=30;I16=12,18,0,0,1130,44170,0,0,1738,102482,0,0,589,12955,0,0;QS=3,0;MQSB=0.748022;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,251:9:0 0,30,255:10:0 +17 1402 . T 0 . DP=31;I16=13,18,0,0,1152,44058,0,0,1798,106082,0,0,589,12977,0,0;QS=3,0;MQSB=0.771348;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,244:9:0 0,30,255:10:0 +17 1403 . T 0 . DP=31;I16=13,18,0,0,1178,45296,0,0,1798,106082,0,0,590,13032,0,0;QS=3,0;MQSB=0.771348;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,249:9:0 0,30,255:10:0 +17 1404 . C 0 . DP=31;I16=13,18,0,0,1102,40838,0,0,1798,106082,0,0,591,13121,0,0;QS=3,0;MQSB=0.771348;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,236:9:0 0,30,244:10:0 +17 1405 . C 0 . DP=30;I16=12,18,0,0,1154,45216,0,0,1738,102482,0,0,593,13243,0,0;QS=3,0;MQSB=0.748022;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,241:9:0 0,27,229:9:0 +17 1406 . T 0 . DP=30;I16=12,18,0,0,1153,44919,0,0,1738,102482,0,0,595,13397,0,0;QS=3,0;MQSB=0.748022;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,248:9:0 0,27,223:9:0 +17 1407 . T 0 . DP=30;I16=11,18,0,0,1074,40182,0,0,1678,98882,0,0,570,12856,0,0;QS=3,0;MQSB=0.720887;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,231:9:0 0,27,215:9:0 +17 1408 . A 0 . DP=30;I16=12,18,0,0,1131,43363,0,0,1738,102482,0,0,596,13592,0,0;QS=3,0;MQSB=0.748022;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,30,244:10:0 0,27,234:9:0 +17 1409 . G 0 . DP=29;I16=12,17,0,0,1082,40752,0,0,1678,98882,0,0,599,13729,0,0;QS=3,0;MQSB=0.753269;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,237:9:0 0,27,204:9:0 +17 1410 . T 0 . DP=29;I16=12,17,0,0,1084,41030,0,0,1678,98882,0,0,601,13841,0,0;QS=3,0;MQSB=0.753269;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,239:9:0 0,27,218:9:0 +17 1411 . T 0 . DP=29;I16=12,17,0,0,958,32550,0,0,1678,98882,0,0,600,13826,0,0;QS=3,0;MQSB=0.753269;MQ0F=0 PL:DP:DV 0,33,250:11:0 0,27,206:9:0 0,27,194:9:0 +17 1412 . A T, 0 . DP=29;I16=11,17,1,0,924,31586,25,625,1649,98041,29,841,573,13159,24,576;QS=2.90842,0.0915751,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.753269;BQB=1;MQ0F=0 PL:DP:DV 0,33,245,33,245,245:11:0 0,2,171,24,174,187:9:1 0,27,192,27,192,192:9:0 +17 1413 . C 0 . DP=29;I16=12,17,0,0,1067,39941,0,0,1678,98882,0,0,591,13521,0,0;QS=3,0;MQSB=0.753269;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,230:9:0 0,27,209:9:0 +17 1414 . T 0 . DP=29;I16=12,17,0,0,1123,44271,0,0,1678,98882,0,0,585,13335,0,0;QS=3,0;MQSB=0.753269;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,236:9:0 0,27,221:9:0 +17 1415 . T 0 . DP=29;I16=12,17,0,0,1000,35254,0,0,1678,98882,0,0,577,13077,0,0;QS=3,0;MQSB=0.753269;MQ0F=0 PL:DP:DV 0,33,246:11:0 0,27,216:9:0 0,27,208:9:0 +17 1416 . A 0 . DP=30;I16=13,17,0,0,1026,36124,0,0,1738,102482,0,0,569,12847,0,0;QS=3,0;MQSB=0.776389;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,208:9:0 0,27,199:9:0 +17 1417 . C 0 . DP=29;I16=13,16,0,0,1111,42941,0,0,1678,98882,0,0,563,12645,0,0;QS=3,0;MQSB=0.781802;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,235:9:0 0,24,211:8:0 +17 1418 . T 0 . DP=29;I16=13,16,0,0,1111,43021,0,0,1678,98882,0,0,557,12471,0,0;QS=3,0;MQSB=0.781802;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,231:9:0 0,24,207:8:0 +17 1419 . A 0 . DP=29;I16=13,16,0,0,1039,38191,0,0,1678,98882,0,0,551,12325,0,0;QS=3,0;MQSB=0.781802;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,222:9:0 0,24,199:8:0 +17 1420 . T 0 . DP=29;I16=13,16,0,0,1039,37885,0,0,1678,98882,0,0,544,12158,0,0;QS=3,0;MQSB=0.781802;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,234:9:0 0,24,185:8:0 +17 1421 . G 0 . DP=31;I16=13,18,0,0,1129,41649,0,0,1798,106082,0,0,536,11970,0,0;QS=3,0;MQSB=0.771348;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,30,247:10:0 0,24,191:8:0 +17 1422 . C 0 . DP=29;I16=13,16,0,0,1075,40645,0,0,1678,98882,0,0,532,11810,0,0;QS=3,0;MQSB=0.781802;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,30,239:10:0 0,18,180:6:0 +17 1423 . T 0 . DP=31;I16=14,17,0,0,1179,45767,0,0,1798,106082,0,0,528,11678,0,0;QS=3,0;MQSB=0.79638;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,36,255:12:0 0,18,183:6:0 +17 1424 . C 0 . DP=30;I16=13,17,0,0,1086,40448,0,0,1738,102482,0,0,527,11575,0,0;QS=3,0;MQSB=0.776389;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,36,255:12:0 0,18,174:6:0 +17 1425 . C 0 . DP=30;I16=13,17,0,0,1124,42974,0,0,1738,102482,0,0,525,11453,0,0;QS=3,0;MQSB=0.776389;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,36,255:12:0 0,18,180:6:0 +17 1426 . T 0 . DP=32;I16=15,17,0,0,1218,47130,0,0,1858,109682,0,0,523,11363,0,0;QS=3,0;MQSB=0.813784;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,36,255:12:0 0,18,188:6:0 +17 1427 . T 0 . DP=32;I16=14,18,0,0,1126,40772,0,0,1827,106923,0,0,524,11306,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,36,255:12:0 0,18,176:6:0 +17 1428 . G 0 . DP=33;I16=15,18,0,0,1188,43596,0,0,1887,110523,0,0,525,11233,0,0;QS=3,0;MQSB=0.930476;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,36,255:12:0 0,18,166:6:0 +17 1429 . G 0 . DP=33;I16=14,18,0,0,1070,37720,0,0,1858,109682,0,0,507,10795,0,0;QS=3,0;MQSB=0.997118;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,33,243:11:0 0,18,148:6:0 +17 1430 . C 0 . DP=33;I16=15,18,0,0,1145,40795,0,0,1887,110523,0,0,529,11193,0,0;QS=3,0;MQSB=0.930476;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,36,247:12:0 0,18,157:6:0 +17 1431 . C 0 . DP=33;I16=15,18,0,0,1160,41686,0,0,1887,110523,0,0,531,11227,0,0;QS=3,0;MQSB=0.930476;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,36,253:12:0 0,18,167:6:0 +17 1432 . A 0 . DP=33;I16=15,18,0,0,1118,39032,0,0,1887,110523,0,0,533,11297,0,0;QS=3,0;MQSB=0.930476;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,36,255:12:0 0,18,169:6:0 +17 1433 . T 0 . DP=34;I16=15,19,0,0,1238,45602,0,0,1947,114123,0,0,535,11403,0,0;QS=3,0;MQSB=0.923533;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,36,255:12:0 0,18,174:6:0 +17 1434 . T 0 . DP=35;I16=15,20,0,0,1269,46757,0,0,2007,117723,0,0,537,11495,0,0;QS=3,0;MQSB=0.916855;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,36,255:12:0 0,18,179:6:0 +17 1435 . T 0 . DP=35;I16=14,20,0,0,1256,46868,0,0,1947,114123,0,0,515,10999,0,0;QS=3,0;MQSB=0.901704;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,36,255:12:0 0,18,180:6:0 +17 1436 . C 0 . DP=34;I16=14,20,0,0,1250,46978,0,0,1947,114123,0,0,544,11790,0,0;QS=3,0;MQSB=0.901704;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,36,255:12:0 0,18,165:6:0 +17 1437 . T 0 . DP=32;I16=13,19,0,0,1222,47206,0,0,1858,109682,0,0,548,11892,0,0;QS=3,0;MQSB=0.993397;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,33,255:11:0 0,15,161:5:0 +17 1438 . C 0 . DP=30;I16=13,17,0,0,1132,43284,0,0,1738,102482,0,0,554,12028,0,0;QS=3,0;MQSB=0.996503;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,30,251:10:0 0,15,159:5:0 +17 1439 . T 0 . DP=30;I16=13,17,0,0,1110,41602,0,0,1738,102482,0,0,560,12196,0,0;QS=3,0;MQSB=0.996503;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,30,255:10:0 0,15,156:5:0 +17 1440 . A 0 . DP=30;I16=12,16,0,0,1062,41028,0,0,1618,95282,0,0,550,12106,0,0;QS=3,0;MQSB=0.995699;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,255:9:0 0,12,144:4:0 +17 1441 . G 0 . DP=30;I16=13,17,0,0,1138,44104,0,0,1738,102482,0,0,574,12576,0,0;QS=3,0;MQSB=0.996503;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,30,244:10:0 0,12,137:4:0 +17 1442 . G 0 . DP=30;I16=13,17,0,0,1064,38534,0,0,1738,102482,0,0,580,12740,0,0;QS=3,0;MQSB=0.996503;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,30,242:10:0 0,12,128:4:0 +17 1443 . T 0 . DP=30;I16=12,17,0,0,1013,36225,0,0,1678,98882,0,0,568,12598,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,30,230:10:0 0,12,133:4:0 +17 1444 . A 0 . DP=30;I16=12,17,0,0,968,33936,0,0,1678,98882,0,0,569,12627,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,27,205:9:0 0,12,132:4:0 +17 1445 . T 0 . DP=30;I16=14,15,0,0,1053,39129,0,0,1678,98882,0,0,585,13161,0,0;QS=3,0;MQSB=0.999762;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,237:9:0 0,15,169:5:0 +17 1446 . T 0 . DP=30;I16=13,16,0,0,1051,38675,0,0,1678,98882,0,0,579,12951,0,0;QS=3,0;MQSB=0.997839;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,229:8:0 0,15,164:5:0 +17 1447 . G 0 . DP=30;I16=14,16,0,0,1110,42692,0,0,1738,102482,0,0,606,13612,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,27,229:9:0 0,15,157:5:0 +17 1448 . G 0 . DP=30;I16=13,16,0,0,1037,37759,0,0,1678,98882,0,0,585,13151,0,0;QS=3,0;MQSB=0.997839;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,217:8:0 0,15,150:5:0 +17 1449 . T 0 . DP=30;I16=14,16,0,0,1051,37869,0,0,1738,102482,0,0,612,13870,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,27,230:9:0 0,15,152:5:0 +17 1450 . A 0 . DP=29;I16=13,15,0,0,1039,38785,0,0,1649,98041,0,0,604,13842,0,0;QS=3,0;MQSB=0.956162;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,224:8:0 0,15,165:5:0 +17 1451 . T 0 . DP=29;I16=13,16,0,0,1046,38586,0,0,1709,101641,0,0,616,14042,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,228:8:0 0,15,158:5:0 +17 1452 . A 0 . DP=31;I16=14,16,0,0,1066,38696,0,0,1769,105241,0,0,604,13924,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,218:8:0 0,15,147:5:0 +17 1453 . T 0 . DP=31;I16=13,17,0,0,1107,42059,0,0,1769,105241,0,0,592,13444,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,199:7:0 0,15,165:5:0 +17 1454 . T 0 . DP=31;I16=14,17,0,0,1139,42711,0,0,1829,108841,0,0,617,14045,0,0;QS=3,0;MQSB=0.962133;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,234:8:0 0,15,166:5:0 +17 1455 . G 0 . DP=31;I16=13,17,0,0,1107,41765,0,0,1769,105241,0,0,592,13420,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,197:7:0 0,15,148:5:0 +17 1456 . T 0 . DP=31;I16=14,17,0,0,1139,42717,0,0,1829,108841,0,0,617,14069,0,0;QS=3,0;MQSB=0.962133;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,215:8:0 0,15,170:5:0 +17 1457 . G 0 . DP=31;I16=14,17,0,0,1129,42071,0,0,1829,108841,0,0,615,14019,0,0;QS=3,0;MQSB=0.962133;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,212:8:0 0,15,164:5:0 +17 1458 . T 0 . DP=31;I16=14,17,0,0,1101,40243,0,0,1829,108841,0,0,613,13997,0,0;QS=3,0;MQSB=0.962133;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,220:8:0 0,15,165:5:0 +17 1459 . C A, 0 . DP=31;I16=14,16,0,1,1164,45842,24,576,1769,105241,60,3600,608,13948,2,4;QS=2.87234,0.12766,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.962133;BQB=1;MQ0F=0 PL:DP:DV 0,54,255,54,255,255:18:0 0,24,224,24,224,224:8:0 9,0,135,21,138,152:5:1 +17 1460 . T 0 . DP=32;I16=15,17,0,0,1243,48813,0,0,1889,112441,0,0,605,13833,0,0;QS=3,0;MQSB=0.960687;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,240:8:0 0,15,170:5:0 +17 1461 . G 0 . DP=32;I16=15,17,0,0,1171,44033,0,0,1889,112441,0,0,600,13692,0,0;QS=3,0;MQSB=0.960687;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,224:8:0 0,15,157:5:0 +17 1462 . C 0 . DP=30;I16=14,15,0,0,1102,42216,0,0,1709,101641,0,0,579,13241,0,0;QS=3,0;MQSB=0.954405;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,202:7:0 0,9,112:3:0 +17 1463 . T 0 . DP=30;I16=15,15,0,0,1128,43348,0,0,1769,105241,0,0,592,13396,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,209:7:0 0,12,139:4:0 +17 1464 . G 0 . DP=31;I16=14,16,0,0,1095,40557,0,0,1769,105241,0,0,563,12665,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,186:6:0 0,15,144:5:0 +17 1465 . T 0 . DP=31;I16=15,16,0,0,1143,42557,0,0,1829,108841,0,0,584,13164,0,0;QS=3,0;MQSB=0.957006;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,204:7:0 0,15,166:5:0 +17 1466 . G 0 . DP=31;I16=15,16,0,0,1122,42294,0,0,1829,108841,0,0,580,13018,0,0;QS=3,0;MQSB=0.957006;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,206:7:0 0,15,163:5:0 +17 1467 . A 0 . DP=31;I16=14,16,0,0,1031,36341,0,0,1769,105241,0,0,569,12803,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,195:7:0 0,15,155:5:0 +17 1468 . A 0 . DP=30;I16=15,15,0,0,991,34477,0,0,1769,105241,0,0,573,12717,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,177:7:0 0,15,158:5:0 +17 1469 . C T, 0 . DP=31;I16=13,15,1,0,1013,37887,38,1444,1649,98041,60,3600,536,12106,9,81;QS=2.94025,0.0597484,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.954405;BQB=1;MQ0F=0 PL:DP:DV 0,16,255,51,255,255:18:1 0,18,178,18,178,178:6:0 0,15,160,15,160,160:5:0 +17 1470 . T 0 . DP=31;I16=16,15,0,0,1110,41070,0,0,1829,108841,0,0,567,12489,0,0;QS=3,0;MQSB=0.951229;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,210:7:0 0,15,165:5:0 +17 1471 . G 0 . DP=30;I16=16,14,0,0,1051,38425,0,0,1769,105241,0,0,564,12348,0,0;QS=3,0;MQSB=0.946202;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,192:7:0 0,12,128:4:0 +17 1472 . T 0 . DP=30;I16=16,14,0,0,1049,38097,0,0,1769,105241,0,0,561,12237,0,0;QS=3,0;MQSB=0.946202;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,200:7:0 0,12,134:4:0 +17 1473 . C 0 . DP=30;I16=16,14,0,0,1058,38526,0,0,1769,105241,0,0,558,12156,0,0;QS=3,0;MQSB=0.946202;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,175:7:0 0,12,140:4:0 +17 1474 . C 0 . DP=30;I16=16,14,0,0,1120,42756,0,0,1769,105241,0,0,555,12105,0,0;QS=3,0;MQSB=0.946202;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,202:7:0 0,12,141:4:0 +17 1475 . T 0 . DP=29;I16=14,14,0,0,1047,40395,0,0,1649,98041,0,0,537,11827,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,208:7:0 0,12,155:4:0 +17 1476 . T G, 0 . DP=31;I16=15,15,1,0,1056,37884,14,196,1769,105241,60,3600,566,12614,10,100;QS=2.944,0.056,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.951229;BQB=1;MQ0F=0 PL:DP:DV 0,57,255,57,255,255:19:0 0,9,177,21,180,183:8:1 0,12,140,12,140,140:4:0 +17 1477 . G 0 . DP=31;I16=16,15,0,0,1150,43390,0,0,1829,108841,0,0,574,12700,0,0;QS=3,0;MQSB=0.951229;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,217:8:0 0,12,138:4:0 +17 1478 . G 0 . DP=31;I16=14,15,0,0,1008,36638,0,0,1709,101641,0,0,542,11982,0,0;QS=3,0;MQSB=0.954405;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,208:8:0 0,9,109:3:0 +17 1479 . C 0 . DP=30;I16=15,15,0,0,1061,38671,0,0,1769,105241,0,0,564,12556,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,211:8:0 0,9,106:3:0 +17 1480 . C 0 . DP=30;I16=15,15,0,0,1083,40355,0,0,1769,105241,0,0,561,12531,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,220:8:0 0,9,103:3:0 +17 1481 . T 0 . DP=30;I16=15,15,0,0,1102,41308,0,0,1769,105241,0,0,558,12532,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,235:8:0 0,9,105:3:0 +17 1482 . G 0 . DP=29;I16=15,14,0,0,1044,38550,0,0,1709,101641,0,0,556,12558,0,0;QS=3,0;MQSB=0.947838;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,210:8:0 0,6,75:2:0 +17 1483 . T 0 . DP=31;I16=14,16,0,0,1042,37190,0,0,1769,105241,0,0,521,11919,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,215:7:0 0,9,100:3:0 +17 1484 . T 0 . DP=31;I16=15,16,0,0,1067,37837,0,0,1829,108841,0,0,547,12587,0,0;QS=3,0;MQSB=0.957006;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,24,216:8:0 0,9,106:3:0 +17 1485 . T 0 . DP=30;I16=15,15,0,0,1027,35863,0,0,1769,105241,0,0,549,12659,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,209:8:0 0,9,93:3:0 +17 1486 . G 0 . DP=29;I16=15,14,0,0,1089,41679,0,0,1709,101641,0,0,551,12707,0,0;QS=3,0;MQSB=0.947838;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,198:7:0 0,9,108:3:0 +17 1487 . G 0 . DP=28;I16=14,14,0,0,973,34723,0,0,1649,98041,0,0,554,12778,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,196:7:0 0,9,97:3:0 +17 1488 . T 0 . DP=28;I16=13,14,0,0,928,32432,0,0,1589,94441,0,0,532,12246,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,176:6:0 0,9,102:3:0 +17 1489 . G 0 . DP=27;I16=13,14,0,0,958,35292,0,0,1589,94441,0,0,535,12361,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,174:6:0 0,9,93:3:0 +17 1490 . A 0 . DP=27;I16=13,14,0,0,928,33108,0,0,1589,94441,0,0,538,12446,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,160:5:0 0,9,94:3:0 +17 1491 . C 0 . DP=27;I16=12,13,0,0,798,26812,0,0,1469,87241,0,0,499,11587,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,108:4:0 0,9,79:3:0 +17 1492 . G 0 . DP=27;I16=13,14,0,0,893,30927,0,0,1589,94441,0,0,543,12527,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,136:5:0 0,9,100:3:0 +17 1493 . G 0 . DP=27;I16=13,13,0,0,907,32761,0,0,1529,90841,0,0,520,11948,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,155:5:0 0,9,106:3:0 +17 1494 . G 0 . DP=27;I16=13,14,0,0,939,33599,0,0,1589,94441,0,0,547,12639,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,156:5:0 0,9,107:3:0 +17 1495 . T 0 . DP=26;I16=12,13,0,0,814,27700,0,0,1469,87241,0,0,524,12048,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,143:5:0 0,9,105:3:0 +17 1496 . G 0 . DP=26;I16=13,13,0,0,969,36751,0,0,1529,90841,0,0,550,12674,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,157:5:0 0,9,107:3:0 +17 1497 . A 0 . DP=27;I16=12,14,0,0,904,32740,0,0,1529,90841,0,0,525,12019,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,166:5:0 0,9,113:3:0 +17 1498 . G 0 . DP=27;I16=13,14,0,0,1002,37852,0,0,1589,94441,0,0,551,12635,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,153:5:0 0,9,112:3:0 +17 1499 . G 0 . DP=28;I16=14,14,0,0,973,34891,0,0,1649,98041,0,0,551,12599,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,146:5:0 0,9,108:3:0 +17 1500 . A 0 . DP=28;I16=14,14,0,0,1023,38115,0,0,1649,98041,0,0,552,12588,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,165:5:0 0,9,115:3:0 +17 1501 . G 0 . DP=28;I16=14,14,0,0,1051,40105,0,0,1649,98041,0,0,551,12505,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,163:5:0 0,9,100:3:0 +17 1502 . C 0 . DP=27;I16=13,14,0,0,963,35241,0,0,1589,94441,0,0,549,12351,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,140:5:0 0,9,105:3:0 +17 1503 . A 0 . DP=28;I16=14,14,0,0,1026,38252,0,0,1649,98041,0,0,546,12176,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,171:5:0 0,9,109:3:0 +17 1504 . G 0 . DP=28;I16=13,14,0,0,1052,41226,0,0,1589,94441,0,0,523,11591,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,163:5:0 0,9,111:3:0 +17 1505 . G 0 . DP=28;I16=14,13,0,0,959,35545,0,0,1589,94441,0,0,517,11295,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,155:5:0 0,9,114:3:0 +17 1506 . G 0 . DP=28;I16=14,14,0,0,1013,37355,0,0,1649,98041,0,0,540,11840,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,139:5:0 0,9,112:3:0 +17 1507 . A 0 . DP=28;I16=14,14,0,0,987,35217,0,0,1649,98041,0,0,538,11792,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,162:5:0 0,9,114:3:0 +17 1508 . C 0 . DP=28;I16=14,14,0,0,1033,38663,0,0,1649,98041,0,0,535,11727,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,137:5:0 0,9,112:3:0 +17 1509 . A 0 . DP=28;I16=15,13,0,0,1028,38610,0,0,1649,98041,0,0,529,11493,0,0;QS=3,0;MQSB=0.942064;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,12,128:4:0 0,9,122:3:0 +17 1510 . G 0 . DP=28;I16=15,13,0,0,1064,40824,0,0,1649,98041,0,0,524,11288,0,0;QS=3,0;MQSB=0.942064;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,12,132:4:0 0,9,111:3:0 +17 1511 . A 0 . DP=28;I16=15,13,0,0,976,34794,0,0,1649,98041,0,0,519,11113,0,0;QS=3,0;MQSB=0.942064;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,12,136:4:0 0,9,110:3:0 +17 1512 . A 0 . DP=28;I16=15,12,0,0,998,37460,0,0,1589,94441,0,0,489,10343,0,0;QS=3,0;MQSB=0.935229;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,142:4:0 0,9,110:3:0 +17 1513 . G 0 . DP=28;I16=14,13,0,0,1014,38940,0,0,1589,94441,0,0,497,10709,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,134:4:0 0,9,108:3:0 +17 1514 . G 0 . DP=28;I16=15,13,0,0,1054,39954,0,0,1649,98041,0,0,504,10768,0,0;QS=3,0;MQSB=0.942064;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,12,134:4:0 0,9,108:3:0 +17 1515 . G 0 . DP=28;I16=14,13,0,0,948,34152,0,0,1589,94441,0,0,488,10564,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,133:4:0 0,9,101:3:0 +17 1516 . T 0 . DP=27;I16=12,13,0,0,811,27385,0,0,1469,87241,0,0,472,10338,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,117:4:0 0,9,106:3:0 +17 1517 . C 0 . DP=27;I16=13,13,0,0,943,35153,0,0,1529,90841,0,0,478,10380,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,12,134:4:0 0,9,97:3:0 +17 1518 . C 0 . DP=28;I16=13,12,0,0,908,33852,0,0,1469,87241,0,0,427,9261,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,132:4:0 0,9,96:3:0 +17 1519 . T 0 . DP=28;I16=15,13,0,0,988,35808,0,0,1649,98041,0,0,475,10337,0,0;QS=3,0;MQSB=0.942064;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,154:5:0 0,9,110:3:0 +17 1520 . G 0 . DP=29;I16=16,13,0,0,1005,36307,0,0,1709,101641,0,0,470,10328,0,0;QS=3,0;MQSB=0.940317;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,18,150:6:0 0,9,104:3:0 +17 1521 . C 0 . DP=28;I16=16,12,0,0,900,30324,0,0,1649,98041,0,0,466,10300,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,164:6:0 0,9,88:3:0 +17 1522 . G 0 . DP=27;I16=15,10,0,0,784,25144,0,0,1469,87241,0,0,442,9956,0,0;QS=3,0;MQSB=0.9171;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,110:5:0 0,9,91:3:0 +17 1523 . T 0 . DP=27;I16=16,11,0,0,921,32001,0,0,1589,94441,0,0,457,10189,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,136:5:0 0,9,108:3:0 +17 1524 . G 0 . DP=27;I16=16,10,0,0,932,34140,0,0,1529,90841,0,0,453,10153,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,12,108:4:0 0,9,103:3:0 +17 1525 . C 0 . DP=27;I16=16,11,0,0,972,35704,0,0,1589,94441,0,0,473,10719,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,113:4:0 0,9,112:3:0 +17 1526 . C 0 . DP=25;I16=14,11,0,0,883,31843,0,0,1469,87241,0,0,470,10684,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,109:4:0 0,9,106:3:0 +17 1527 . C 0 . DP=24;I16=14,10,0,0,867,31999,0,0,1440,86400,0,0,466,10572,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,107:4:0 0,9,112:3:0 +17 1528 . T 0 . DP=23;I16=13,10,0,0,869,33133,0,0,1380,82800,0,0,463,10483,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,114:4:0 0,9,113:3:0 +17 1529 . G 0 . DP=23;I16=13,10,0,0,812,29432,0,0,1380,82800,0,0,459,10365,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,108:4:0 0,9,104:3:0 +17 1530 . C 0 . DP=24;I16=13,10,0,0,819,30073,0,0,1380,82800,0,0,446,10186,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,137:5:0 0,9,106:3:0 +17 1531 . C 0 . DP=24;I16=13,11,0,0,877,32969,0,0,1440,86400,0,0,452,10190,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,144:5:0 0,9,105:3:0 +17 1532 . T 0 . DP=24;I16=13,11,0,0,887,33721,0,0,1440,86400,0,0,449,10135,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,165:5:0 0,9,120:3:0 +17 1533 . T 0 . DP=23;I16=13,10,0,0,793,27987,0,0,1380,82800,0,0,447,10101,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,146:5:0 0,9,107:3:0 +17 1534 . C 0 . DP=23;I16=14,9,0,0,847,31627,0,0,1380,82800,0,0,446,10086,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,153:5:0 0,9,109:3:0 +17 1535 . A 0 . DP=23;I16=14,9,0,0,770,26604,0,0,1380,82800,0,0,444,9990,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,144:5:0 0,9,99:3:0 +17 1536 . C 0 . DP=24;I16=15,9,0,0,826,28984,0,0,1440,86400,0,0,442,9914,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,138:5:0 0,9,110:3:0 +17 1537 . A 0 . DP=24;I16=14,9,0,0,844,31384,0,0,1380,82800,0,0,416,9234,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,149:5:0 0,9,115:3:0 +17 1538 . A 0 . DP=24;I16=15,9,0,0,909,34727,0,0,1440,86400,0,0,440,9826,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,154:5:0 0,9,112:3:0 +17 1539 . G 0 . DP=24;I16=15,9,0,0,913,35327,0,0,1440,86400,0,0,439,9815,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,149:5:0 0,9,117:3:0 +17 1540 . C 0 . DP=23;I16=15,8,0,0,828,30260,0,0,1380,82800,0,0,438,9776,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,146:5:0 0,9,102:3:0 +17 1541 . C 0 . DP=23;I16=15,8,0,0,823,30615,0,0,1380,82800,0,0,437,9759,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,142:5:0 0,9,108:3:0 +17 1542 . C 0 . DP=25;I16=16,8,0,0,893,33843,0,0,1440,86400,0,0,435,9715,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,147:5:0 0,12,131:4:0 +17 1543 . C 0 . DP=25;I16=16,8,0,0,880,33206,0,0,1440,86400,0,0,434,9696,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,141:5:0 0,12,136:4:0 +17 1544 . T 0 . DP=25;I16=16,8,0,0,899,34405,0,0,1440,86400,0,0,431,9603,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,150:5:0 0,12,148:4:0 +17 1545 . G 0 . DP=25;I16=16,8,0,0,874,32636,0,0,1440,86400,0,0,428,9536,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,146:5:0 0,12,129:4:0 +17 1546 . G 0 . DP=24;I16=15,8,0,0,796,28796,0,0,1380,82800,0,0,425,9443,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,130:5:0 0,9,110:3:0 +17 1547 . A 0 . DP=23;I16=15,8,0,0,837,30945,0,0,1380,82800,0,0,448,9996,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,176:6:0 0,9,112:3:0 +17 1548 . A 0 . DP=23;I16=14,8,0,0,812,30830,0,0,1320,79200,0,0,421,9319,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,173:5:0 0,9,115:3:0 +17 1549 . G 0 . DP=23;I16=15,8,0,0,870,33642,0,0,1380,82800,0,0,444,9912,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,174:6:0 0,9,114:3:0 +17 1550 . G 0 . DP=23;I16=15,8,0,0,790,28502,0,0,1380,82800,0,0,442,9900,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,154:6:0 0,9,109:3:0 +17 1551 . A 0 . DP=23;I16=15,8,0,0,802,28596,0,0,1380,82800,0,0,440,9908,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,173:6:0 0,9,107:3:0 +17 1552 . A 0 . DP=21;I16=14,7,0,0,792,30156,0,0,1260,75600,0,0,438,9836,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,196:6:0 0,9,110:3:0 +17 1553 . A 0 . DP=21;I16=13,7,0,0,738,28112,0,0,1200,72000,0,0,411,9159,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,251:11:0 0,18,192:6:0 0,9,115:3:0 +17 1554 . G 0 . DP=21;I16=14,7,0,0,763,28221,0,0,1260,75600,0,0,434,9752,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,171:6:0 0,9,101:3:0 +17 1555 . T 0 . DP=21;I16=14,7,0,0,726,26234,0,0,1260,75600,0,0,432,9740,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,252:12:0 0,18,169:6:0 0,9,108:3:0 +17 1556 . T 0 . DP=21;I16=14,7,0,0,745,26971,0,0,1260,75600,0,0,429,9697,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,253:12:0 0,18,177:6:0 0,9,110:3:0 +17 1557 . G 0 . DP=22;I16=15,7,0,0,801,29689,0,0,1320,79200,0,0,426,9672,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,166:6:0 0,9,101:3:0 +17 1558 . T 0 . DP=22;I16=15,6,0,0,720,25620,0,0,1260,75600,0,0,404,9244,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,131:5:0 0,9,112:3:0 +17 1559 . T 0 . DP=22;I16=15,7,0,0,712,24690,0,0,1320,79200,0,0,417,9439,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,248:13:0 0,18,158:6:0 0,9,103:3:0 +17 1560 . T 0 . DP=21;I16=14,7,0,0,736,26560,0,0,1260,75600,0,0,412,9284,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,251:12:0 0,18,170:6:0 0,9,112:3:0 +17 1561 . T 0 . DP=21;I16=14,7,0,0,706,24776,0,0,1260,75600,0,0,406,9102,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,241:12:0 0,18,174:6:0 0,9,106:3:0 +17 1562 . G 0 . DP=21;I16=14,7,0,0,765,28655,0,0,1260,75600,0,0,399,8893,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,181:6:0 0,9,108:3:0 +17 1563 . G 0 . DP=22;I16=13,7,0,0,713,26255,0,0,1200,72000,0,0,360,8176,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,147:5:0 0,9,108:3:0 +17 1564 . G 0 . DP=22;I16=13,8,0,0,721,25457,0,0,1260,75600,0,0,368,8218,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,173:6:0 0,9,95:3:0 +17 1565 . A 0 . DP=21;I16=14,7,0,0,724,25888,0,0,1260,75600,0,0,380,8352,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,162:6:0 0,6,71:2:0 +17 1566 . T 0 . DP=21;I16=13,7,0,0,698,25286,0,0,1200,72000,0,0,364,8086,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,143:5:0 0,6,78:2:0 +17 1567 . C 0 . DP=20;I16=12,6,0,0,652,24422,0,0,1080,64800,0,0,351,7881,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,104:3:0 0,6,72:2:0 +17 1568 . T 0 . DP=20;I16=13,7,0,0,711,26125,0,0,1200,72000,0,0,363,7871,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,157:5:0 0,6,74:2:0 +17 1569 . C 0 . DP=19;I16=12,6,0,0,676,25850,0,0,1080,64800,0,0,351,7669,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,128:4:0 0,6,76:2:0 +17 1570 . T 0 . DP=19;I16=12,7,0,0,700,26750,0,0,1140,68400,0,0,353,7583,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,149:5:0 0,6,71:2:0 +17 1571 . G 0 . DP=19;I16=12,6,0,0,639,23361,0,0,1080,64800,0,0,343,7441,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,125:4:0 0,6,70:2:0 +17 1572 . C 0 . DP=19;I16=11,6,0,0,640,24568,0,0,1020,61200,0,0,328,7202,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,125:4:0 0,6,70:2:0 +17 1573 . A 0 . DP=19;I16=11,4,0,0,565,21475,0,0,900,54000,0,0,304,6900,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,132:4:0 0,3,40:1:0 +17 1574 . C 0 . DP=19;I16=12,5,0,0,636,24076,0,0,1020,61200,0,0,318,6948,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,128:4:0 0,3,38:1:0 +17 1575 . C 0 . DP=19;I16=11,6,0,0,610,22742,0,0,1020,61200,0,0,296,6272,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,125:4:0 0,6,71:2:0 +17 1576 . C 0 . DP=19;I16=12,6,0,0,675,25821,0,0,1080,64800,0,0,315,6785,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,133:4:0 0,6,78:2:0 +17 1577 . T 0 . DP=17;I16=11,6,0,0,650,25330,0,0,1020,61200,0,0,310,6692,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,118:3:0 0,6,77:2:0 +17 1578 . C 0 . DP=17;I16=10,6,0,0,622,24364,0,0,960,57600,0,0,279,5943,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,84:2:0 0,6,77:2:0 +17 1579 . A 0 . DP=17;I16=11,6,0,0,596,22326,0,0,1020,61200,0,0,298,6464,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,116:3:0 0,6,80:2:0 +17 1580 . G 0 . DP=17;I16=11,6,0,0,651,25195,0,0,1020,61200,0,0,292,6380,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,109:3:0 0,6,77:2:0 +17 1581 . C 0 . DP=17;I16=11,6,0,0,586,21418,0,0,1020,61200,0,0,286,6316,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,103:3:0 0,6,71:2:0 +17 1582 . C 0 . DP=18;I16=11,7,0,0,639,23491,0,0,1080,64800,0,0,280,6272,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,109:3:0 0,6,75:2:0 +17 1583 . T 0 . DP=16;I16=10,6,0,0,591,22349,0,0,960,57600,0,0,276,6196,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,112:3:0 0,6,74:2:0 +17 1584 . G 0 . DP=15;I16=10,5,0,0,563,21283,0,0,900,54000,0,0,272,6086,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,105:3:0 0,3,39:1:0 +17 1585 . G 0 . DP=16;I16=10,5,0,0,494,17160,0,0,900,54000,0,0,251,5703,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,244:11:0 0,9,103:3:0 0,3,30:1:0 +17 1586 . A 0 . DP=15;I16=10,3,0,0,470,17200,0,0,780,46800,0,0,237,5273,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,223:10:0 0,6,79:2:0 0,3,42:1:0 +17 1587 . C 0 . DP=15;I16=11,4,0,0,508,17900,0,0,900,54000,0,0,264,5852,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,247:11:0 0,9,94:3:0 0,3,31:1:0 +17 1588 . A 0 . DP=15;I16=11,4,0,0,511,17939,0,0,900,54000,0,0,262,5806,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,232:11:0 0,9,105:3:0 0,3,41:1:0 +17 1589 . A 0 . DP=15;I16=11,4,0,0,536,19584,0,0,900,54000,0,0,259,5725,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,249:11:0 0,9,106:3:0 0,3,42:1:0 +17 1590 . C 0 . DP=15;I16=10,5,0,0,514,18228,0,0,900,54000,0,0,257,5657,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,231:10:0 0,9,104:3:0 0,6,71:2:0 +17 1591 . T 0 . DP=15;I16=10,5,0,0,515,18559,0,0,900,54000,0,0,256,5602,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,241:10:0 0,9,85:3:0 0,6,73:2:0 +17 1592 . T 0 . DP=15;I16=10,5,0,0,503,17345,0,0,900,54000,0,0,255,5561,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,225:10:0 0,9,107:3:0 0,6,62:2:0 +17 1593 . G 0 . DP=15;I16=10,5,0,0,540,19930,0,0,900,54000,0,0,254,5534,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,9,106:3:0 0,6,60:2:0 +17 1594 . T 0 . DP=15;I16=10,5,0,0,535,19445,0,0,900,54000,0,0,252,5472,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,234:10:0 0,9,106:3:0 0,6,80:2:0 +17 1595 . G 0 . DP=15;I16=10,4,0,0,494,17940,0,0,840,50400,0,0,225,4801,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,213:9:0 0,9,105:3:0 0,6,69:2:0 +17 1596 . C 0 . DP=15;I16=10,4,0,0,479,17011,0,0,840,50400,0,0,233,5151,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,200:9:0 0,9,111:3:0 0,6,74:2:0 +17 1597 . C 0 . DP=15;I16=10,5,0,0,489,16941,0,0,900,54000,0,0,245,5285,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,195:9:0 0,12,127:4:0 0,6,73:2:0 +17 1598 . C 0 . DP=15;I16=10,5,0,0,514,18282,0,0,900,54000,0,0,244,5240,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,207:9:0 0,12,133:4:0 0,6,68:2:0 +17 1599 . A 0 . DP=14;I16=8,5,0,0,436,15330,0,0,780,46800,0,0,225,4851,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,182:8:0 0,9,103:3:0 0,6,76:2:0 +17 1600 . T 0 . DP=13;I16=8,5,0,0,456,16430,0,0,780,46800,0,0,226,4876,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,193:8:0 0,9,105:3:0 0,6,79:2:0 +17 1601 . C 0 . DP=13;I16=8,4,0,0,431,15861,0,0,720,43200,0,0,208,4554,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,171:7:0 0,9,108:3:0 0,6,78:2:0 +17 1602 . T 0 . DP=13;I16=7,5,0,0,439,16867,0,0,720,43200,0,0,228,4968,0,0;QS=3,0;MQSB=0.95494;MQ0F=0 PL:DP:DV 0,21,179:7:0 0,9,115:3:0 0,6,85:2:0 +17 1603 . G 0 . DP=12;I16=7,5,0,0,455,17407,0,0,720,43200,0,0,230,5034,0,0;QS=3,0;MQSB=0.95494;MQ0F=0 PL:DP:DV 0,21,202:7:0 0,9,111:3:0 0,6,75:2:0 +17 1604 . G 0 . DP=12;I16=7,5,0,0,362,11620,0,0,720,43200,0,0,232,5112,0,0;QS=3,0;MQSB=0.95494;MQ0F=0 PL:DP:DV 0,21,163:7:0 0,9,84:3:0 0,6,66:2:0 +17 1605 . T 0 . DP=12;I16=7,5,0,0,410,14230,0,0,720,43200,0,0,234,5202,0,0;QS=3,0;MQSB=0.95494;MQ0F=0 PL:DP:DV 0,21,190:7:0 0,9,97:3:0 0,6,61:2:0 +17 1606 . G 0 . DP=12;I16=7,4,0,0,370,12738,0,0,660,39600,0,0,211,4679,0,0;QS=3,0;MQSB=0.964642;MQ0F=0 PL:DP:DV 0,18,165:6:0 0,9,91:3:0 0,6,56:2:0 +17 1607 . A 0 . DP=12;I16=7,4,0,0,337,11369,0,0,660,39600,0,0,226,5222,0,0;QS=3,0;MQSB=0.964642;MQ0F=0 PL:DP:DV 0,21,161:7:0 0,6,70:2:0 0,6,55:2:0 +17 1608 . C 0 . DP=12;I16=7,4,0,0,366,12898,0,0,660,39600,0,0,211,4727,0,0;QS=3,0;MQSB=0.964642;MQ0F=0 PL:DP:DV 0,18,141:6:0 0,9,111:3:0 0,6,62:2:0 +17 1609 . C 0 . DP=11;I16=6,5,0,0,365,12889,0,0,660,39600,0,0,237,5393,0,0;QS=3,0;MQSB=0.950952;MQ0F=0 PL:DP:DV 0,18,149:6:0 0,9,110:3:0 0,6,71:2:0 +17 1610 . C 0 . DP=11;I16=5,5,0,0,313,10713,0,0,600,36000,0,0,213,4819,0,0;QS=3,0;MQSB=0.952347;MQ0F=0 PL:DP:DV 0,15,127:5:0 0,9,106:3:0 0,6,57:2:0 +17 1611 . C 0 . DP=11;I16=6,5,0,0,398,14904,0,0,660,39600,0,0,238,5454,0,0;QS=3,0;MQSB=0.950952;MQ0F=0 PL:DP:DV 0,18,180:6:0 0,9,110:3:0 0,6,67:2:0 +17 1612 . T 0 . DP=11;I16=6,5,0,0,409,15421,0,0,660,39600,0,0,238,5472,0,0;QS=3,0;MQSB=0.950952;MQ0F=0 PL:DP:DV 0,18,174:6:0 0,9,107:3:0 0,6,83:2:0 +17 1613 . C 0 . DP=11;I16=6,5,0,0,372,12904,0,0,660,39600,0,0,238,5498,0,0;QS=3,0;MQSB=0.950952;MQ0F=0 PL:DP:DV 0,18,169:6:0 0,9,99:3:0 0,6,63:2:0 +17 1614 . A 0 . DP=11;I16=6,5,0,0,353,12139,0,0,660,39600,0,0,238,5532,0,0;QS=3,0;MQSB=0.950952;MQ0F=0 PL:DP:DV 0,18,147:6:0 0,9,98:3:0 0,6,69:2:0 +17 1615 . C 0 . DP=11;I16=6,5,0,0,366,13080,0,0,660,39600,0,0,238,5574,0,0;QS=3,0;MQSB=0.950952;MQ0F=0 PL:DP:DV 0,18,171:6:0 0,9,105:3:0 0,6,51:2:0 +17 1616 . T 0 . DP=11;I16=6,3,0,0,348,13606,0,0,540,32400,0,0,187,4323,0,0;QS=3,0;MQSB=0.924584;MQ0F=0 PL:DP:DV 0,15,159:5:0 0,9,105:3:0 0,3,42:1:0 +17 1617 . C 0 . DP=12;I16=6,3,0,0,330,12316,0,0,540,32400,0,0,185,4279,0,0;QS=3,0;MQSB=0.924584;MQ0F=0 PL:DP:DV 0,15,146:5:0 0,9,105:3:0 0,3,42:1:0 +17 1618 . A 0 . DP=12;I16=5,6,0,0,385,14199,0,0,629,36841,0,0,244,5636,0,0;QS=3,0;MQSB=0.891517;MQ0F=0 PL:DP:DV 0,18,151:6:0 0,9,93:3:0 0,6,81:2:0 +17 1619 . G 0 . DP=11;I16=5,6,0,0,377,13119,0,0,629,36841,0,0,242,5544,0,0;QS=3,0;MQSB=0.891517;MQ0F=0 PL:DP:DV 0,18,166:6:0 0,9,84:3:0 0,6,67:2:0 +17 1620 . C 0 . DP=11;I16=5,5,0,0,323,10965,0,0,569,33241,0,0,215,4839,0,0;QS=3,0;MQSB=0.857112;MQ0F=0 PL:DP:DV 0,15,142:5:0 0,9,78:3:0 0,6,56:2:0 +17 1621 . C 0 . DP=12;I16=5,7,0,0,363,11779,0,0,689,40441,0,0,263,6021,0,0;QS=3,0;MQSB=0.896474;MQ0F=0 PL:DP:DV 0,21,174:7:0 0,9,80:3:0 0,6,56:2:0 +17 1622 . A 0 . DP=12;I16=5,7,0,0,365,12105,0,0,689,40441,0,0,261,5965,0,0;QS=3,0;MQSB=0.896474;MQ0F=0 PL:DP:DV 0,21,176:7:0 0,9,81:3:0 0,6,52:2:0 +17 1623 . C 0 . DP=12;I16=5,5,0,0,325,10979,0,0,569,33241,0,0,208,4620,0,0;QS=3,0;MQSB=0.857112;MQ0F=0 PL:DP:DV 0,18,155:6:0 0,9,84:3:0 0,3,37:1:0 +17 1624 . C 0 . DP=12;I16=4,6,0,0,336,11718,0,0,569,33241,0,0,211,4799,0,0;QS=3,0;MQSB=0.895781;MQ0F=0 PL:DP:DV 0,18,162:6:0 0,9,88:3:0 0,3,39:1:0 +17 1625 . A 0 . DP=12;I16=4,7,0,0,375,13503,0,0,629,36841,0,0,234,5386,0,0;QS=3,0;MQSB=0.924449;MQ0F=0 PL:DP:DV 0,18,158:6:0 0,9,93:3:0 0,6,80:2:0 +17 1626 . G 0 . DP=12;I16=5,7,0,0,358,11490,0,0,689,40441,0,0,249,5645,0,0;QS=3,0;MQSB=0.896474;MQ0F=0 PL:DP:DV 0,21,158:7:0 0,9,83:3:0 0,6,63:2:0 +17 1627 . A 0 . DP=12;I16=5,7,0,0,363,11609,0,0,689,40441,0,0,246,5590,0,0;QS=3,0;MQSB=0.896474;MQ0F=0 PL:DP:DV 0,21,165:7:0 0,9,75:3:0 0,6,72:2:0 +17 1628 . C 0 . DP=12;I16=5,7,0,0,357,11583,0,0,689,40441,0,0,243,5545,0,0;QS=3,0;MQSB=0.896474;MQ0F=0 PL:DP:DV 0,21,165:7:0 0,9,80:3:0 0,6,57:2:0 +17 1629 . T 0 . DP=13;I16=6,7,0,0,451,16079,0,0,749,44041,0,0,240,5510,0,0;QS=3,0;MQSB=0.899815;MQ0F=0 PL:DP:DV 0,21,187:7:0 0,12,120:4:0 0,6,79:2:0 +17 1630 . T 0 . DP=13;I16=6,7,0,0,403,13323,0,0,749,44041,0,0,237,5435,0,0;QS=3,0;MQSB=0.899815;MQ0F=0 PL:DP:DV 0,21,169:7:0 0,12,111:4:0 0,6,73:2:0 +17 1631 . C 0 . DP=12;I16=6,5,0,0,354,12046,0,0,660,39600,0,0,210,4744,0,0;QS=3,0;MQSB=0.950952;MQ0F=0 PL:DP:DV 0,21,184:7:0 0,6,67:2:0 0,6,61:2:0 +17 1632 . C 0 . DP=13;I16=6,7,0,0,387,12175,0,0,749,44041,0,0,232,5262,0,0;QS=3,0;MQSB=0.899815;MQ0F=0 PL:DP:DV 0,24,188:8:0 0,9,82:3:0 0,6,61:2:0 +17 1633 . A 0 . DP=13;I16=6,7,0,0,404,13272,0,0,749,44041,0,0,230,5166,0,0;QS=3,0;MQSB=0.899815;MQ0F=0 PL:DP:DV 0,24,183:8:0 0,9,86:3:0 0,6,73:2:0 +17 1634 . C 0 . DP=13;I16=6,6,0,0,328,9716,0,0,689,40441,0,0,203,4457,0,0;QS=3,0;MQSB=0.864013;MQ0F=0 PL:DP:DV 0,21,151:7:0 0,9,80:3:0 0,6,59:2:0 +17 1635 . G 0 . DP=14;I16=6,8,0,0,419,12831,0,0,809,47641,0,0,226,5010,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,24,180:8:0 0,12,108:4:0 0,6,59:2:0 +17 1636 . A 0 . DP=14;I16=6,8,0,0,418,13400,0,0,809,47641,0,0,225,4951,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,24,179:8:0 0,12,110:4:0 0,6,66:2:0 +17 1637 . C 0 . DP=14;I16=6,8,0,0,422,13498,0,0,809,47641,0,0,224,4906,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,24,185:8:0 0,12,110:4:0 0,6,60:2:0 +17 1638 . A 0 . DP=17;I16=9,7,0,0,513,17167,0,0,929,54841,0,0,216,4790,0,0;QS=3,0;MQSB=0.892753;MQ0F=0 PL:DP:DV 0,24,191:8:0 0,18,149:6:0 0,6,78:2:0 +17 1639 . G 0 . DP=17;I16=9,8,0,0,552,18844,0,0,989,58441,0,0,223,4765,0,0;QS=3,0;MQSB=0.91051;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,18,150:6:0 0,6,68:2:0 +17 1640 . G 0 . DP=17;I16=8,6,0,0,414,13296,0,0,809,47641,0,0,171,3467,0,0;QS=3,0;MQSB=0.875173;MQ0F=0 PL:DP:DV 0,18,150:6:0 0,18,151:6:0 0,6,51:2:0 +17 1641 . C 0 . DP=18;I16=9,8,0,0,511,16289,0,0,989,58441,0,0,225,4709,0,0;QS=3,0;MQSB=0.91051;MQ0F=0 PL:DP:DV 0,27,188:9:0 0,18,167:6:0 0,6,65:2:0 +17 1642 . T 0 . DP=17;I16=8,7,0,0,519,18513,0,0,869,51241,0,0,217,4613,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,18,170:6:0 0,18,168:6:0 0,9,102:3:0 +17 1643 . C 0 . DP=16;I16=7,9,0,0,508,16910,0,0,929,54841,0,0,255,5361,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,24,193:8:0 0,18,169:6:0 0,6,56:2:0 +17 1644 . C 0 . DP=15;I16=6,9,0,0,514,18056,0,0,869,51241,0,0,259,5401,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,21,209:7:0 0,18,165:6:0 0,6,54:2:0 +17 1645 . A 0 . DP=15;I16=6,9,0,0,520,18852,0,0,869,51241,0,0,263,5457,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,21,213:7:0 0,18,173:6:0 0,6,49:2:0 +17 1646 . G 0 . DP=15;I16=6,7,0,0,440,15526,0,0,780,46800,0,0,217,4279,0,0;QS=3,0;MQSB=0.961166;MQ0F=0 PL:DP:DV 0,18,185:6:0 0,15,148:5:0 0,6,48:2:0 +17 1647 . C 0 . DP=15;I16=6,9,0,0,433,13883,0,0,869,51241,0,0,271,5617,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,21,190:7:0 0,18,139:6:0 0,6,35:2:0 +17 1648 . C 0 . DP=15;I16=6,9,0,0,495,16965,0,0,869,51241,0,0,275,5721,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,21,203:7:0 0,18,159:6:0 0,6,44:2:0 +17 1649 . T 0 . DP=15;I16=6,9,0,0,516,18122,0,0,869,51241,0,0,279,5841,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,21,187:7:0 0,18,182:6:0 0,6,56:2:0 +17 1650 . C 0 . DP=15;I16=6,7,0,0,405,13551,0,0,749,44041,0,0,240,5028,0,0;QS=3,0;MQSB=0.899815;MQ0F=0 PL:DP:DV 0,18,161:6:0 0,18,169:6:0 0,3,13:1:0 +17 1651 . G 0 . DP=17;I16=5,9,0,0,424,13328,0,0,778,44882,0,0,249,5335,0,0;QS=3,0;MQSB=0.965069;MQ0F=0 PL:DP:DV 0,18,150:6:0 0,15,128:5:0 0,9,86:3:0 +17 1652 . G 0 . DP=18;I16=7,9,0,0,532,18602,0,0,898,52082,0,0,267,5673,0,0;QS=3,0;MQSB=0.994413;MQ0F=0 PL:DP:DV 0,24,212:8:0 0,18,168:6:0 0,6,54:2:0 +17 1653 . C 0 . DP=18;I16=8,10,0,0,581,19565,0,0,1018,59282,0,0,300,6490,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,24,208:8:0 0,21,175:7:0 0,9,82:3:0 +17 1654 . A T, 0 . DP=18;I16=8,9,0,1,516,16718,15,225,958,55682,60,3600,285,6219,22,484;QS=2.93213,0.0678733,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.99606;BQB=1;MQ0F=0 PL:DP:DV 0,9,155,21,158,162:8:1 0,21,179,21,179,179:7:0 0,9,78,9,78,78:3:0 +17 1655 . C 0 . DP=18;I16=8,10,0,0,565,19017,0,0,1018,59282,0,0,313,6887,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,24,198:8:0 0,21,180:7:0 0,9,79:3:0 +17 1656 . C 0 . DP=19;I16=9,9,0,0,557,18013,0,0,1018,59282,0,0,295,6515,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,202:8:0 0,21,165:7:0 0,9,80:3:0 +17 1657 . T A, 0 . DP=18;I16=8,9,0,1,580,20362,15,225,989,58441,29,841,301,6641,25,625;QS=2.93243,0.0675676,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.99606;BQB=1;MQ0F=0 PL:DP:DV 0,24,206,24,206,206:8:0 0,6,158,18,161,165:7:1 0,9,85,9,85,85:3:0 +17 1658 . T 0 . DP=19;I16=8,10,0,0,573,19127,0,0,1018,59282,0,0,332,7412,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,24,187:8:0 0,21,189:7:0 0,9,91:3:0 +17 1659 . C 0 . DP=20;I16=8,10,0,0,609,21517,0,0,1049,62041,0,0,338,7578,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,24,219:8:0 0,21,189:7:0 0,9,80:3:0 +17 1660 . A 0 . DP=21;I16=8,11,0,0,641,23219,0,0,1078,62882,0,0,385,8901,0,0;QS=3,0;MQSB=0.992359;MQ0F=0 PL:DP:DV 0,21,172:7:0 0,24,219:8:0 0,12,127:4:0 +17 1661 . G 0 . DP=21;I16=7,13,0,0,639,21739,0,0,1107,63723,0,0,412,9598,0,0;QS=3,0;MQSB=0.999215;MQ0F=0 PL:DP:DV 0,24,209:8:0 0,24,193:8:0 0,12,98:4:0 +17 1662 . C 0 . DP=21;I16=8,12,0,0,641,21423,0,0,1107,63723,0,0,407,9465,0,0;QS=3,0;MQSB=0.988166;MQ0F=0 PL:DP:DV 0,21,192:7:0 0,27,211:9:0 0,12,100:4:0 +17 1663 . C 0 . DP=20;I16=7,11,0,0,577,19507,0,0,1018,59282,0,0,394,9204,0,0;QS=3,0;MQSB=0.983729;MQ0F=0 PL:DP:DV 0,21,178:7:0 0,21,192:7:0 0,12,101:4:0 +17 1664 . A C, 0 . DP=20;I16=6,10,0,1,530,17982,13,169,898,52082,29,841,358,8422,25,625;QS=2.93953,0.0604651,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.998738;BQB=1;MQ0F=0 PL:DP:DV 0,18,167,18,167,167:6:0 0,7,154,18,157,159:7:1 0,12,109,12,109,109:4:0 +17 1665 . T C, 0 . DP=20;I16=7,11,1,1,592,20170,58,1924,1018,59282,89,4441,396,9188,39,821;QS=2.5913,0.408696,0;VDB=0.1;SGB=0.346553;RPB=0.222222;MQB=0.611111;MQSB=0.988166;BQB=0.944444;MQ0F=0 PL:DP:DV 0,21,185,21,185,185:7:0 0,27,222,27,222,222:9:0 35,0,51,41,57,90:4:2 +17 1666 . G 0 . DP=20;I16=8,12,0,0,614,19760,0,0,1107,63723,0,0,435,9947,0,0;QS=3,0;MQSB=0.988166;MQ0F=0 PL:DP:DV 0,21,173:7:0 0,27,206:9:0 0,12,111:4:0 +17 1667 . G 0 . DP=20;I16=8,11,0,0,617,21033,0,0,1078,62882,0,0,410,9276,0,0;QS=3,0;MQSB=0.992359;MQ0F=0 PL:DP:DV 0,21,183:7:0 0,24,195:8:0 0,12,115:4:0 +17 1668 . A 0 . DP=20;I16=7,10,0,0,570,19908,0,0,958,55682,0,0,369,8365,0,0;QS=3,0;MQSB=0.989343;MQ0F=0 PL:DP:DV 0,18,158:6:0 0,21,186:7:0 0,12,124:4:0 +17 1669 . C 0 . DP=20;I16=8,12,0,0,640,21336,0,0,1107,63723,0,0,435,9857,0,0;QS=3,0;MQSB=0.988166;MQ0F=0 PL:DP:DV 0,21,172:7:0 0,27,216:9:0 0,12,115:4:0 +17 1670 . A 0 . DP=23;I16=9,13,0,0,765,27363,0,0,1258,73682,0,0,410,9234,0,0;QS=3,0;MQSB=0.991121;MQ0F=0 PL:DP:DV 0,27,215:9:0 0,27,233:9:0 0,12,129:4:0 +17 1671 . G 0 . DP=23;I16=9,13,0,0,703,23631,0,0,1258,73682,0,0,412,9206,0,0;QS=3,0;MQSB=0.991121;MQ0F=0 PL:DP:DV 0,27,214:9:0 0,27,210:9:0 0,12,106:4:0 +17 1672 . T 0 . DP=23;I16=9,13,0,0,724,24700,0,0,1258,73682,0,0,414,9202,0,0;QS=3,0;MQSB=0.991121;MQ0F=0 PL:DP:DV 0,27,203:9:0 0,27,232:9:0 0,12,111:4:0 +17 1673 . T 0 . DP=25;I16=8,13,0,0,719,25183,0,0,1198,70082,0,0,372,8248,0,0;QS=3,0;MQSB=0.983744;MQ0F=0 PL:DP:DV 0,27,221:9:0 0,24,212:8:0 0,12,112:4:0 +17 1674 . C 0 . DP=25;I16=8,14,0,0,755,26561,0,0,1289,76441,0,0,389,8417,0,0;QS=3,0;MQSB=0.892142;MQ0F=0 PL:DP:DV 0,33,244:11:0 0,21,206:7:0 0,12,96:4:0 +17 1675 . C 0 . DP=25;I16=9,15,0,0,705,22355,0,0,1347,78123,0,0,447,9897,0,0;QS=3,0;MQSB=0.996008;MQ0F=0 PL:DP:DV 0,33,222:11:0 0,30,212:10:0 0,9,65:3:0 +17 1676 . G 0 . DP=25;I16=6,15,0,0,660,21708,0,0,1167,67323,0,0,383,8265,0,0;QS=3,0;MQSB=0.993205;MQ0F=0 PL:DP:DV 0,33,222:11:0 0,21,170:7:0 0,9,96:3:0 +17 1677 . C 0 . DP=25;I16=9,13,0,0,681,22869,0,0,1289,76441,0,0,394,8510,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,33,225:11:0 0,24,198:8:0 0,9,74:3:0 +17 1678 . C 0 . DP=25;I16=9,15,0,0,775,26785,0,0,1347,78123,0,0,438,9496,0,0;QS=3,0;MQSB=0.996008;MQ0F=0 PL:DP:DV 0,33,235:11:0 0,30,231:10:0 0,9,83:3:0 +17 1679 . A 0 . DP=25;I16=8,15,0,0,762,27552,0,0,1287,74523,0,0,412,8858,0,0;QS=3,0;MQSB=0.999479;MQ0F=0 PL:DP:DV 0,33,235:11:0 0,27,219:9:0 0,9,106:3:0 +17 1680 . G 0 . DP=26;I16=9,17,0,0,843,29213,0,0,1467,85323,0,0,459,10021,0,0;QS=3,0;MQSB=0.999637;MQ0F=0 PL:DP:DV 0,33,253:11:0 0,33,232:11:0 0,12,108:4:0 +17 1681 . C 0 . DP=26;I16=8,15,0,0,681,21293,0,0,1318,77282,0,0,407,8999,0,0;QS=3,0;MQSB=0.974802;MQ0F=0 PL:DP:DV 0,33,223:11:0 0,27,191:9:0 0,9,69:3:0 +17 1682 . G 0 . DP=25;I16=9,16,0,0,728,22560,0,0,1407,81723,0,0,455,9877,0,0;QS=3,0;MQSB=0.998399;MQ0F=0 PL:DP:DV 0,30,222:10:0 0,33,208:11:0 0,12,98:4:0 +17 1683 . T 0 . DP=25;I16=8,15,0,0,807,29159,0,0,1287,74523,0,0,403,8567,0,0;QS=3,0;MQSB=0.999479;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,30,235:10:0 0,9,91:3:0 +17 1684 . T 0 . DP=25;I16=8,15,0,0,802,28774,0,0,1318,77282,0,0,438,9612,0,0;QS=3,0;MQSB=0.974802;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,30,237:10:0 0,12,107:4:0 +17 1685 . G 0 . DP=24;I16=8,14,0,0,759,27319,0,0,1258,73682,0,0,413,8999,0,0;QS=3,0;MQSB=0.979255;MQ0F=0 PL:DP:DV 0,24,216:8:0 0,30,242:10:0 0,12,110:4:0 +17 1686 . C 0 . DP=24;I16=8,15,0,0,793,28073,0,0,1318,77282,0,0,438,9656,0,0;QS=3,0;MQSB=0.974802;MQ0F=0 PL:DP:DV 0,27,225:9:0 0,30,241:10:0 0,12,103:4:0 +17 1687 . C 0 . DP=24;I16=7,14,0,0,741,26765,0,0,1198,70082,0,0,388,8458,0,0;QS=3,0;MQSB=0.966484;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,27,229:9:0 0,12,106:4:0 +17 1688 . C 0 . DP=24;I16=8,15,0,0,794,28736,0,0,1318,77282,0,0,431,9605,0,0;QS=3,0;MQSB=0.974802;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,30,221:10:0 0,12,120:4:0 +17 1689 . T A, 0 . DP=24;I16=8,15,0,1,805,29443,33,1089,1287,74523,60,3600,421,9311,25,625;QS=2.74419,0.255814,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,27,224,27,224,224:9:0 0,33,255,33,255,255:11:0 21,0,79,30,82,106:4:1 +17 1690 . C 0 . DP=24;I16=8,16,0,0,864,32420,0,0,1347,78123,0,0,445,10033,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,242:9:0 0,33,255:11:0 0,12,95:4:0 +17 1691 . T 0 . DP=22;I16=7,14,0,0,734,27150,0,0,1167,67323,0,0,421,9525,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,225:9:0 0,30,242:10:0 0,6,57:2:0 +17 1692 . G 0 . DP=22;I16=7,13,0,0,678,24110,0,0,1107,63723,0,0,400,9176,0,0;QS=3,0;MQSB=0.999215;MQ0F=0 PL:DP:DV 0,24,218:8:0 0,30,218:10:0 0,6,61:2:0 +17 1693 . T 0 . DP=24;I16=10,13,0,0,795,28363,0,0,1318,77282,0,0,444,10422,0,0;QS=3,0;MQSB=0.995682;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,30,235:10:0 0,12,104:4:0 +17 1694 . T 0 . DP=24;I16=10,13,0,0,771,26775,0,0,1318,77282,0,0,448,10602,0,0;QS=3,0;MQSB=0.995682;MQ0F=0 PL:DP:DV 0,27,221:9:0 0,30,232:10:0 0,12,114:4:0 +17 1695 . C 0 . DP=24;I16=10,14,0,0,811,28517,0,0,1347,78123,0,0,454,10806,0,0;QS=3,0;MQSB=0.98469;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,33,239:11:0 0,12,121:4:0 +17 1696 . T 0 . DP=23;I16=10,13,0,0,825,30819,0,0,1287,74523,0,0,455,10869,0,0;QS=3,0;MQSB=0.976718;MQ0F=0 PL:DP:DV 0,24,219:8:0 0,33,255:11:0 0,12,108:4:0 +17 1697 . G 0 . DP=23;I16=10,13,0,0,767,26757,0,0,1287,74523,0,0,455,10897,0,0;QS=3,0;MQSB=0.976718;MQ0F=0 PL:DP:DV 0,24,208:8:0 0,33,246:11:0 0,12,112:4:0 +17 1698 . C A, 0 . DP=21;I16=10,10,0,1,726,27088,27,729,1169,69241,29,841,451,10903,6,36;QS=2.91148,0.0885246,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.99938;BQB=1;MQ0F=0 PL:DP:DV 0,24,229,24,229,229:8:0 0,0,190,24,193,207:9:1 0,12,111,12,111,111:4:0 +17 1699 . T 0 . DP=21;I16=9,10,0,0,698,25826,0,0,1078,62882,0,0,408,9692,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,21,203:7:0 0,24,219:8:0 0,12,115:4:0 +17 1700 . G 0 . DP=20;I16=9,10,0,0,696,25850,0,0,1078,62882,0,0,409,9705,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,21,216:7:0 0,24,215:8:0 0,12,110:4:0 +17 1701 . T 0 . DP=20;I16=9,11,0,0,711,25539,0,0,1138,66482,0,0,435,10353,0,0;QS=3,0;MQSB=0.997118;MQ0F=0 PL:DP:DV 0,24,207:8:0 0,24,210:8:0 0,12,125:4:0 +17 1702 . T 0 . DP=20;I16=8,11,0,0,671,24367,0,0,1078,62882,0,0,410,9712,0,0;QS=3,0;MQSB=0.992359;MQ0F=0 PL:DP:DV 0,24,214:8:0 0,21,193:7:0 0,12,115:4:0 +17 1703 . T 0 . DP=20;I16=9,10,0,0,648,22696,0,0,1078,62882,0,0,410,9708,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,21,197:7:0 0,24,195:8:0 0,12,114:4:0 +17 1704 . T 0 . DP=20;I16=10,10,0,0,711,25771,0,0,1169,69241,0,0,435,10341,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,24,208:8:0 0,21,208:7:0 0,15,128:5:0 +17 1705 . C 0 . DP=20;I16=10,10,0,0,744,28388,0,0,1169,69241,0,0,436,10312,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,24,232:8:0 0,21,213:7:0 0,15,120:5:0 +17 1706 . T 0 . DP=20;I16=10,10,0,0,775,30329,0,0,1169,69241,0,0,436,10246,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,21,219:7:0 0,15,145:5:0 +17 1707 . C 0 . DP=21;I16=9,11,0,0,724,26998,0,0,1169,69241,0,0,410,9518,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,27,235:9:0 0,18,180:6:0 0,15,134:5:0 +17 1708 . T 0 . DP=21;I16=9,12,0,0,740,27282,0,0,1229,72841,0,0,410,9430,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,30,229:10:0 0,18,187:6:0 0,15,132:5:0 +17 1709 . A 0 . DP=21;I16=9,11,0,0,675,23509,0,0,1169,69241,0,0,386,8734,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,27,210:9:0 0,18,166:6:0 0,15,131:5:0 +17 1710 . C 0 . DP=22;I16=9,13,0,0,755,26817,0,0,1289,76441,0,0,412,9306,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,33,236:11:0 0,18,181:6:0 0,15,128:5:0 +17 1711 . C 0 . DP=22;I16=9,13,0,0,786,28790,0,0,1289,76441,0,0,413,9223,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,33,250:11:0 0,18,169:6:0 0,15,138:5:0 +17 1712 . A 0 . DP=22;I16=9,13,0,0,824,31342,0,0,1289,76441,0,0,414,9162,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,33,252:11:0 0,18,198:6:0 0,15,136:5:0 +17 1713 . G 0 . DP=23;I16=8,14,0,0,823,31285,0,0,1289,76441,0,0,405,8993,0,0;QS=3,0;MQSB=0.892142;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,189:6:0 0,12,118:4:0 +17 1714 . A 0 . DP=23;I16=9,13,0,0,763,27439,0,0,1289,76441,0,0,402,8818,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,36,234:12:0 0,18,190:6:0 0,12,101:4:0 +17 1715 . A 0 . DP=23;I16=9,14,0,0,900,35416,0,0,1349,80041,0,0,414,8878,0,0;QS=3,0;MQSB=0.907354;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,206:6:0 0,15,145:5:0 +17 1716 . G 0 . DP=23;I16=9,14,0,0,844,31500,0,0,1349,80041,0,0,414,8822,0,0;QS=3,0;MQSB=0.907354;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,188:6:0 0,15,129:5:0 +17 1717 . T 0 . DP=24;I16=9,15,0,0,854,30878,0,0,1409,83641,0,0,414,8794,0,0;QS=3,0;MQSB=0.904837;MQ0F=0 PL:DP:DV 0,39,253:13:0 0,18,185:6:0 0,15,122:5:0 +17 1718 . G 0 . DP=24;I16=9,14,0,0,806,29332,0,0,1349,80041,0,0,390,8170,0,0;QS=3,0;MQSB=0.907354;MQ0F=0 PL:DP:DV 0,36,249:12:0 0,18,188:6:0 0,15,124:5:0 +17 1719 . C 0 . DP=26;I16=11,14,0,0,857,30717,0,0,1469,87241,0,0,407,8675,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,173:6:0 0,12,98:4:0 +17 1720 . C 0 . DP=26;I16=11,14,0,0,898,33274,0,0,1469,87241,0,0,409,8645,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,166:6:0 0,12,99:4:0 +17 1721 . C 0 . DP=26;I16=10,14,0,0,846,30642,0,0,1409,83641,0,0,388,8258,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,187:6:0 0,12,119:4:0 +17 1722 . T 0 . DP=25;I16=11,13,0,0,876,33054,0,0,1409,83641,0,0,406,8540,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,174:5:0 0,15,123:5:0 +17 1723 . T 0 . DP=25;I16=11,14,0,0,835,28861,0,0,1469,87241,0,0,420,8728,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,167:5:0 0,15,130:5:0 +17 1724 . C 0 . DP=25;I16=11,14,0,0,903,33735,0,0,1469,87241,0,0,422,8800,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,164:5:0 0,15,139:5:0 +17 1725 . C G, 0 . DP=25;I16=11,13,0,1,835,29699,25,625,1409,83641,60,3600,406,8576,18,324;QS=2.95164,0.0483559,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.929204;BQB=1;MQ0F=0 PL:DP:DV 0,20,255,42,255,255:15:1 0,15,153,15,153,153:5:0 0,15,132,15,132,132:5:0 +17 1726 . C 0 . DP=25;I16=11,14,0,0,932,35588,0,0,1469,87241,0,0,426,9028,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,165:5:0 0,15,122:5:0 +17 1727 . T 0 . DP=25;I16=10,14,0,0,862,32080,0,0,1409,83641,0,0,404,8556,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,167:5:0 0,12,120:4:0 +17 1728 . C 0 . DP=25;I16=11,14,0,0,915,33845,0,0,1469,87241,0,0,429,9173,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,156:5:0 0,15,144:5:0 +17 1729 . C 0 . DP=25;I16=10,14,0,0,919,35797,0,0,1409,83641,0,0,406,8668,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,142:5:0 0,12,128:4:0 +17 1730 . T 0 . DP=24;I16=10,14,0,0,849,30711,0,0,1409,83641,0,0,433,9393,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,138:4:0 0,15,148:5:0 +17 1731 . C 0 . DP=24;I16=10,14,0,0,907,34875,0,0,1409,83641,0,0,434,9472,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,123:4:0 0,15,140:5:0 +17 1732 . A 0 . DP=24;I16=11,13,0,0,816,28582,0,0,1409,83641,0,0,436,9580,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,123:4:0 0,15,143:5:0 +17 1733 . C 0 . DP=25;I16=12,13,0,0,869,31451,0,0,1469,87241,0,0,438,9666,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,116:4:0 0,15,136:5:0 +17 1734 . C 0 . DP=25;I16=12,13,0,0,926,35482,0,0,1469,87241,0,0,440,9730,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,122:4:0 0,15,141:5:0 +17 1735 . T 0 . DP=26;I16=13,13,0,0,935,35169,0,0,1529,90841,0,0,442,9822,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,112:4:0 0,15,148:5:0 +17 1736 . G 0 . DP=25;I16=11,11,0,0,829,31469,0,0,1289,76441,0,0,380,8416,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,72:2:0 0,12,118:4:0 +17 1737 . A 0 . DP=25;I16=12,12,0,0,842,30606,0,0,1409,83641,0,0,422,9312,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,76:2:0 0,15,131:5:0 +17 1738 . C 0 . DP=24;I16=12,12,0,0,835,30251,0,0,1409,83641,0,0,450,10010,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,78:3:0 0,15,130:5:0 +17 1739 . C 0 . DP=23;I16=10,12,0,0,831,32123,0,0,1289,76441,0,0,428,9432,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,55:2:0 0,12,135:4:0 +17 1740 . A 0 . DP=23;I16=11,12,0,0,774,27126,0,0,1349,80041,0,0,456,10126,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,56:2:0 0,15,139:5:0 +17 1741 . C 0 . DP=23;I16=11,12,0,0,850,32314,0,0,1349,80041,0,0,459,10217,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,70:2:0 0,15,136:5:0 +17 1742 . T 0 . DP=23;I16=11,12,0,0,866,33204,0,0,1349,80041,0,0,462,10330,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,72:2:0 0,15,144:5:0 +17 1743 . C 0 . DP=23;I16=11,12,0,0,894,35176,0,0,1349,80041,0,0,464,10414,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,74:2:0 0,15,138:5:0 +17 1744 . T 0 . DP=23;I16=11,11,0,0,857,33579,0,0,1289,76441,0,0,459,10469,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,80:2:0 0,15,156:5:0 +17 1745 . G 0 . DP=23;I16=11,12,0,0,882,34572,0,0,1349,80041,0,0,464,10442,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,78:2:0 0,15,142:5:0 +17 1746 . G 0 . DP=24;I16=12,11,0,0,836,31102,0,0,1349,80041,0,0,456,10312,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,69:2:0 0,18,151:6:0 +17 1747 . G 0 . DP=24;I16=12,11,0,0,839,31729,0,0,1349,80041,0,0,455,10239,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,75:2:0 0,18,154:6:0 +17 1748 . G 0 . DP=24;I16=11,12,0,0,843,31857,0,0,1349,80041,0,0,434,9664,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,42:1:0 0,18,154:6:0 +17 1749 . A 0 . DP=25;I16=13,11,0,0,864,31748,0,0,1409,83641,0,0,451,10063,0,0;QS=3,0;MQSB=0.950498;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,72:2:0 0,21,172:7:0 +17 1750 . A 0 . DP=25;I16=13,12,0,0,905,33667,0,0,1469,87241,0,0,451,10013,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,56:2:0 0,21,187:7:0 +17 1751 . A 0 . DP=25;I16=13,12,0,0,908,33658,0,0,1469,87241,0,0,449,9987,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,67:2:0 0,21,183:7:0 +17 1752 . T 0 . DP=23;I16=12,11,0,0,838,31088,0,0,1380,82800,0,0,449,9987,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,71:2:0 0,18,170:6:0 +17 1753 . C 0 . DP=23;I16=12,11,0,0,869,33595,0,0,1380,82800,0,0,448,9960,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,77:2:0 0,18,163:6:0 +17 1754 . C 0 . DP=23;I16=11,11,0,0,830,31628,0,0,1320,79200,0,0,431,9699,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,3,42:1:0 0,18,163:6:0 +17 1755 . C 0 . DP=23;I16=12,11,0,0,856,33082,0,0,1380,82800,0,0,446,9972,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,61:2:0 0,18,165:6:0 +17 1756 . T 0 . DP=22;I16=11,11,0,0,858,33720,0,0,1320,79200,0,0,445,9961,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,77:2:0 0,18,179:6:0 +17 1757 . C 0 . DP=22;I16=11,11,0,0,869,34651,0,0,1320,79200,0,0,444,9972,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,78:2:0 0,18,176:6:0 +17 1758 . A 0 . DP=22;I16=11,11,0,0,865,34205,0,0,1320,79200,0,0,442,9954,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,81:2:0 0,18,177:6:0 +17 1759 . G 0 . DP=22;I16=11,11,0,0,833,31965,0,0,1320,79200,0,0,439,9905,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,77:2:0 0,18,159:6:0 +17 1760 . C 0 . DP=22;I16=11,11,0,0,849,33441,0,0,1320,79200,0,0,436,9874,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,79:2:0 0,18,159:6:0 +17 1761 . A 0 . DP=22;I16=11,11,0,0,730,25766,0,0,1320,79200,0,0,432,9810,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,75:2:0 0,18,153:6:0 +17 1762 . C 0 . DP=21;I16=11,10,0,0,767,28667,0,0,1260,75600,0,0,429,9761,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,76:2:0 0,18,160:6:0 +17 1763 . C 0 . DP=21;I16=11,10,0,0,789,30115,0,0,1260,75600,0,0,426,9726,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,72:2:0 0,18,162:6:0 +17 1764 . C 0 . DP=21;I16=11,10,0,0,821,32443,0,0,1260,75600,0,0,423,9705,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,72:2:0 0,18,167:6:0 +17 1765 . T 0 . DP=21;I16=11,10,0,0,814,31746,0,0,1260,75600,0,0,420,9698,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,83:2:0 0,18,179:6:0 +17 1766 . C 0 . DP=21;I16=11,10,0,0,796,30564,0,0,1260,75600,0,0,417,9705,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,71:2:0 0,18,162:6:0 +17 1767 . C 0 . DP=21;I16=11,10,0,0,779,29559,0,0,1260,75600,0,0,414,9726,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,73:2:0 0,18,163:6:0 +17 1768 . C 0 . DP=21;I16=11,10,0,0,798,30670,0,0,1260,75600,0,0,411,9761,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,68:2:0 0,18,160:6:0 +17 1769 . T 0 . DP=21;I16=11,10,0,0,819,32179,0,0,1260,75600,0,0,406,9712,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,77:2:0 0,18,184:6:0 +17 1770 . G 0 . DP=19;I16=11,8,0,0,699,26453,0,0,1140,68400,0,0,403,9679,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,68:2:0 0,18,158:6:0 +17 1771 . A 0 . DP=18;I16=10,8,0,0,707,27853,0,0,1080,64800,0,0,401,9659,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,42:1:0 0,18,177:6:0 +17 1772 . G 0 . DP=18;I16=10,8,0,0,669,25513,0,0,1080,64800,0,0,398,9600,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,38:1:0 0,18,159:6:0 +17 1773 . C 0 . DP=17;I16=10,7,0,0,675,26897,0,0,1020,61200,0,0,396,9550,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,3,39:1:0 0,18,172:6:0 +17 1774 . A 0 . DP=17;I16=10,7,0,0,653,25153,0,0,1020,61200,0,0,394,9508,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,3,39:1:0 0,18,172:6:0 +17 1775 . T 0 . DP=17;I16=10,7,0,0,605,22253,0,0,1020,61200,0,0,391,9423,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,3,38:1:0 0,18,156:6:0 +17 1776 . A 0 . DP=17;I16=10,7,0,0,610,22124,0,0,1020,61200,0,0,388,9344,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,254:10:0 0,3,35:1:0 0,18,166:6:0 +17 1777 . C 0 . DP=18;I16=11,7,0,0,661,24975,0,0,1080,64800,0,0,385,9271,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,35:1:0 0,18,158:6:0 +17 1778 . C 0 . DP=18;I16=11,7,0,0,680,25970,0,0,1080,64800,0,0,383,9205,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,31:1:0 0,18,172:6:0 +17 1779 . C 0 . DP=18;I16=11,7,0,0,703,27663,0,0,1080,64800,0,0,381,9147,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,34:1:0 0,18,174:6:0 +17 1780 . T 0 . DP=18;I16=11,7,0,0,672,26000,0,0,1080,64800,0,0,378,9048,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,33:1:0 0,18,177:6:0 +17 1781 . A 0 . DP=19;I16=10,6,0,0,579,21377,0,0,960,57600,0,0,328,7804,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,0,0:0:0 0,15,160:5:0 +17 1782 . C 0 . DP=20;I16=11,9,0,0,715,26603,0,0,1200,72000,0,0,382,8892,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,47:2:0 0,18,156:6:0 +17 1783 . T 0 . DP=20;I16=11,9,0,0,755,29057,0,0,1200,72000,0,0,381,8743,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,68:2:0 0,18,184:6:0 +17 1784 . C 0 . DP=20;I16=10,9,0,0,723,28017,0,0,1140,68400,0,0,360,8212,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,62:2:0 0,15,151:5:0 +17 1785 . T 0 . DP=20;I16=10,10,0,0,766,29878,0,0,1200,72000,0,0,359,8089,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,66:2:0 0,15,168:5:0 +17 1786 . G 0 . DP=22;I16=11,11,0,0,841,32323,0,0,1320,79200,0,0,359,7985,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,68:2:0 0,15,158:5:0 +17 1787 . G 0 . DP=22;I16=11,11,0,0,806,30294,0,0,1320,79200,0,0,361,7903,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,68:2:0 0,15,148:5:0 +17 1788 . C 0 . DP=22;I16=11,11,0,0,858,33674,0,0,1320,79200,0,0,362,7796,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,67:2:0 0,15,158:5:0 +17 1789 . A 0 . DP=23;I16=11,12,0,0,797,28705,0,0,1380,82800,0,0,363,7715,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,69:2:0 0,15,157:5:0 +17 1790 . C 0 . DP=23;I16=11,12,0,0,852,31816,0,0,1380,82800,0,0,365,7661,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,63:2:0 0,15,153:5:0 +17 1791 . A 0 . DP=23;I16=11,12,0,0,830,30484,0,0,1380,82800,0,0,367,7635,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,61:2:0 0,15,155:5:0 +17 1792 . A 0 . DP=23;I16=11,12,0,0,862,32760,0,0,1380,82800,0,0,368,7588,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,67:2:0 0,15,161:5:0 +17 1793 . G 0 . DP=23;I16=11,12,0,0,813,29603,0,0,1380,82800,0,0,369,7571,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,61:2:0 0,15,126:5:0 +17 1794 . C 0 . DP=21;I16=9,12,0,0,736,26472,0,0,1260,75600,0,0,370,7484,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,48:2:0 0,9,96:3:0 +17 1795 . C 0 . DP=21;I16=9,12,0,0,763,28807,0,0,1260,75600,0,0,371,7427,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,45:2:0 0,9,100:3:0 +17 1796 . C 0 . DP=21;I16=9,12,0,0,782,29718,0,0,1260,75600,0,0,372,7400,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,52:2:0 0,9,102:3:0 +17 1797 . A 0 . DP=21;I16=9,12,0,0,704,25190,0,0,1260,75600,0,0,373,7403,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,59:2:0 0,9,92:3:0 +17 1798 . C 0 . DP=21;I16=9,12,0,0,759,28119,0,0,1260,75600,0,0,374,7436,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,49:2:0 0,9,99:3:0 +17 1799 . C 0 . DP=22;I16=9,13,0,0,796,29520,0,0,1320,79200,0,0,375,7499,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,56:2:0 0,12,131:4:0 +17 1800 . C 0 . DP=22;I16=9,13,0,0,866,34352,0,0,1320,79200,0,0,376,7542,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,63:2:0 0,12,138:4:0 +17 1801 . T 0 . DP=22;I16=9,13,0,0,838,32282,0,0,1320,79200,0,0,377,7615,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,63:2:0 0,12,150:4:0 +17 1802 . G 0 . DP=22;I16=9,13,0,0,844,32894,0,0,1320,79200,0,0,378,7718,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,60:2:0 0,12,137:4:0 +17 1803 . C 0 . DP=22;I16=9,13,0,0,837,32691,0,0,1320,79200,0,0,377,7751,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,60:2:0 0,12,143:4:0 +17 1804 . A 0 . DP=23;I16=9,14,0,0,793,28517,0,0,1380,82800,0,0,376,7814,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,54:2:0 0,12,144:4:0 +17 1805 . A 0 . DP=23;I16=9,14,0,0,810,29148,0,0,1380,82800,0,0,376,7908,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,67:2:0 0,12,138:4:0 +17 1806 . A 0 . DP=23;I16=9,14,0,0,816,29932,0,0,1380,82800,0,0,376,8034,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,61:2:0 0,12,139:4:0 +17 1807 . G 0 . DP=22;I16=9,13,0,0,837,32299,0,0,1320,79200,0,0,375,8091,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,67:2:0 0,12,142:4:0 +17 1808 . C 0 . DP=21;I16=9,11,0,0,705,25519,0,0,1200,72000,0,0,354,7716,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,53:2:0 0,12,140:4:0 +17 1809 . C 0 . DP=22;I16=10,12,0,0,789,29123,0,0,1320,79200,0,0,371,8091,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,55:2:0 0,12,143:4:0 +17 1810 . C 0 . DP=21;I16=10,11,0,0,754,27902,0,0,1260,75600,0,0,370,8084,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,51:2:0 0,12,145:4:0 +17 1811 . C 0 . DP=22;I16=11,11,0,0,837,32353,0,0,1320,79200,0,0,368,8056,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,61:2:0 0,12,146:4:0 +17 1812 . T 0 . DP=22;I16=11,11,0,0,830,31782,0,0,1320,79200,0,0,365,7955,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,60:2:0 0,12,151:4:0 +17 1813 . G 0 . DP=21;I16=11,10,0,0,789,29971,0,0,1260,75600,0,0,363,7879,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,63:2:0 0,12,135:4:0 +17 1814 . A 0 . DP=21;I16=11,10,0,0,780,29356,0,0,1260,75600,0,0,361,7827,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,63:2:0 0,12,148:4:0 +17 1815 . G 0 . DP=21;I16=11,10,0,0,742,27064,0,0,1260,75600,0,0,358,7748,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,56:2:0 0,12,135:4:0 +17 1816 . G 0 . DP=21;I16=11,10,0,0,702,24670,0,0,1260,75600,0,0,355,7691,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,49:2:0 0,12,124:4:0 +17 1817 . C 0 . DP=20;I16=11,9,0,0,701,25263,0,0,1200,72000,0,0,353,7655,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,58:2:0 0,12,134:4:0 +17 1818 . C 0 . DP=20;I16=11,8,0,0,665,23987,0,0,1140,68400,0,0,326,7014,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,53:2:0 0,12,132:4:0 +17 1819 . C 0 . DP=18;I16=9,9,0,0,580,20092,0,0,1080,64800,0,0,351,7641,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,38:2:0 0,12,124:4:0 +17 1820 . G 0 . DP=18;I16=9,9,0,0,589,19883,0,0,1080,64800,0,0,351,7659,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,58:2:0 0,12,117:4:0 +17 1821 . C 0 . DP=18;I16=9,9,0,0,619,22131,0,0,1080,64800,0,0,351,7693,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,60:2:0 0,12,131:4:0 +17 1822 . C 0 . DP=18;I16=9,9,0,0,655,24177,0,0,1080,64800,0,0,350,7694,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,58:2:0 0,12,131:4:0 +17 1823 . C 0 . DP=19;I16=10,9,0,0,703,26765,0,0,1140,68400,0,0,349,7713,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,62:2:0 0,12,138:4:0 +17 1824 . T 0 . DP=19;I16=10,9,0,0,714,27628,0,0,1140,68400,0,0,349,7751,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,69:2:0 0,12,149:4:0 +17 1825 . G 0 . DP=19;I16=10,9,0,0,682,24804,0,0,1140,68400,0,0,347,7709,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,61:2:0 0,12,129:4:0 +17 1826 . T 0 . DP=19;I16=10,9,0,0,643,22525,0,0,1140,68400,0,0,345,7687,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,62:2:0 0,12,141:4:0 +17 1827 . G 0 . DP=19;I16=10,9,0,0,722,27844,0,0,1140,68400,0,0,343,7685,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,66:2:0 0,12,134:4:0 +17 1828 . G 0 . DP=18;I16=10,8,0,0,619,21719,0,0,1080,64800,0,0,342,7702,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,61:2:0 0,9,100:3:0 +17 1829 . C 0 . DP=19;I16=9,9,0,0,576,19228,0,0,1080,64800,0,0,323,7413,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,59:3:0 0,9,103:3:0 +17 1830 . G 0 . DP=19;I16=9,9,0,0,582,19586,0,0,1080,64800,0,0,321,7379,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,82:3:0 0,9,80:3:0 +17 1831 . T 0 . DP=20;I16=10,8,0,0,605,21015,0,0,1080,64800,0,0,294,6736,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,106:4:0 0,9,101:3:0 +17 1832 . C 0 . DP=19;I16=9,9,0,0,675,25747,0,0,1080,64800,0,0,319,7359,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,110:4:0 0,9,105:3:0 +17 1833 . T 0 . DP=18;I16=8,8,0,0,565,20733,0,0,960,57600,0,0,295,6747,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,9,105:3:0 0,9,106:3:0 +17 1834 . C 0 . DP=19;I16=9,9,0,0,654,24424,0,0,1037,61489,0,0,321,7399,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,104:4:0 0,9,107:3:0 +17 1835 . T 0 . DP=18;I16=9,9,0,0,641,23505,0,0,1037,61489,0,0,347,7965,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,123:4:0 0,9,115:3:0 +17 1836 . C 0 . DP=18;I16=9,9,0,0,657,24427,0,0,1037,61489,0,0,350,8016,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,127:4:0 0,9,108:3:0 +17 1837 . C 0 . DP=18;I16=9,9,0,0,586,20044,0,0,1037,61489,0,0,352,8030,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,233:11:0 0,12,114:4:0 0,9,108:3:0 +17 1838 . C 0 . DP=18;I16=9,9,0,0,655,24607,0,0,1037,61489,0,0,354,8056,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,120:4:0 0,9,107:3:0 +17 1839 . T 0 . DP=18;I16=9,7,0,0,557,20543,0,0,917,54289,0,0,321,7369,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,30,231:10:0 0,9,103:3:0 0,9,119:3:0 +17 1840 . C 0 . DP=18;I16=9,9,0,0,637,23295,0,0,1037,61489,0,0,358,8144,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,116:4:0 0,9,109:3:0 +17 1841 . C 0 . DP=18;I16=9,9,0,0,622,22458,0,0,1037,61489,0,0,360,8206,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,252:11:0 0,12,121:4:0 0,9,108:3:0 +17 1842 . C 0 . DP=18;I16=9,9,0,0,672,26064,0,0,1037,61489,0,0,362,8280,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,124:4:0 0,9,108:3:0 +17 1843 . T 0 . DP=18;I16=9,9,0,0,630,22746,0,0,1037,61489,0,0,364,8366,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,243:11:0 0,12,131:4:0 0,9,107:3:0 +17 1844 . T 0 . DP=18;I16=9,9,0,0,618,21618,0,0,1037,61489,0,0,366,8464,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,240:11:0 0,12,137:4:0 0,9,98:3:0 +17 1845 . G 0 . DP=18;I16=9,9,0,0,644,23976,0,0,1037,61489,0,0,368,8574,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,138:4:0 0,9,82:3:0 +17 1846 . C 0 . DP=18;I16=9,9,0,0,687,26809,0,0,1037,61489,0,0,370,8696,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,129:4:0 0,9,100:3:0 +17 1847 . T 0 . DP=18;I16=9,9,0,0,675,25529,0,0,1037,61489,0,0,373,8829,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,132:4:0 0,6,76:2:0 +17 1848 . G 0 . DP=18;I16=9,9,0,0,597,20845,0,0,1037,61489,0,0,377,8973,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,118:4:0 0,6,64:2:0 +17 1849 . T 0 . DP=20;I16=9,10,0,0,614,20770,0,0,1097,65089,0,0,380,9078,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,119:4:0 0,6,71:2:0 +17 1850 . C 0 . DP=19;I16=8,11,0,0,684,25154,0,0,1097,65089,0,0,409,9769,0,0;QS=3,0;MQSB=0.902014;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,120:4:0 0,3,37:1:0 +17 1851 . A 0 . DP=20;I16=9,11,0,0,738,27838,0,0,1157,68689,0,0,413,9847,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,143:4:0 0,3,41:1:0 +17 1852 . G 0 . DP=19;I16=8,11,0,0,639,22239,0,0,1097,65089,0,0,392,9264,0,0;QS=3,0;MQSB=0.902014;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,117:4:0 0,3,36:1:0 +17 1853 . G 0 . DP=20;I16=9,11,0,0,627,20873,0,0,1157,68689,0,0,396,9322,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,127:5:0 0,3,38:1:0 +17 1854 . A 0 . DP=22;I16=10,11,0,0,674,22428,0,0,1217,72289,0,0,401,9397,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,145:5:0 0,3,38:1:0 +17 1855 . C 0 . DP=22;I16=10,12,0,0,771,27949,0,0,1277,75889,0,0,407,9441,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,132:5:0 0,3,37:1:0 +17 1856 . A 0 . DP=22;I16=10,12,0,0,806,30230,0,0,1277,75889,0,0,412,9456,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,146:5:0 0,3,41:1:0 +17 1857 . G 0 . DP=22;I16=10,12,0,0,699,23919,0,0,1277,75889,0,0,416,9442,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,134:5:0 0,3,35:1:0 +17 1858 . T 0 . DP=23;I16=10,13,0,0,773,26797,0,0,1337,79489,0,0,419,9399,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,148:5:0 0,3,37:1:0 +17 1859 . G 0 . DP=23;I16=10,13,0,0,798,28594,0,0,1337,79489,0,0,423,9379,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,146:5:0 0,3,36:1:0 +17 1860 . G 0 . DP=23;I16=10,13,0,0,726,23842,0,0,1337,79489,0,0,425,9283,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,126:5:0 0,3,33:1:0 +17 1861 . T 0 . DP=23;I16=10,13,0,0,741,24793,0,0,1337,79489,0,0,425,9113,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,143:5:0 0,3,39:1:0 +17 1862 . C 0 . DP=23;I16=10,12,0,0,738,25732,0,0,1277,75889,0,0,403,8487,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,135:5:0 0,3,34:1:0 +17 1863 . C 0 . DP=24;I16=10,13,0,0,804,29186,0,0,1337,79489,0,0,400,8232,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,133:5:0 0,3,36:1:0 +17 1864 . T 0 . DP=24;I16=11,11,0,0,766,27572,0,0,1277,75889,0,0,392,8174,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,125:4:0 0,3,37:1:0 +17 1865 . G 0 . DP=24;I16=11,13,0,0,860,31394,0,0,1397,83089,0,0,425,8621,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,154:5:0 0,3,38:1:0 +17 1866 . G 0 . DP=24;I16=11,13,0,0,795,27503,0,0,1397,83089,0,0,425,8551,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,152:5:0 0,3,36:1:0 +17 1867 . C 0 . DP=24;I16=9,13,0,0,726,24886,0,0,1320,79200,0,0,375,7263,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,122:5:0 0,3,38:1:0 +17 1868 . C 0 . DP=24;I16=11,12,0,0,857,32293,0,0,1337,79489,0,0,411,8311,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,118:4:0 0,3,41:1:0 +17 1869 . A T, 0 . DP=24;I16=6,9,5,4,531,19001,268,8660,857,50689,540,32400,273,5667,152,2866;QS=1.4724,1.5276,0;VDB=0.928022;SGB=-11.9537;RPB=0.984127;MQB=0.96464;MQSB=0.931547;BQB=0.359155;MQ0F=0 PL:DP:DV 115,0,224,148,245,255:18:7 16,0,104,28,107,128:5:1 42,3,0,42,3,42:1:1 +17 1870 . C 0 . DP=25;I16=11,13,0,0,804,27826,0,0,1397,83089,0,0,425,8591,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,127:5:0 0,3,36:1:0 +17 1871 . C 0 . DP=25;I16=11,14,0,0,761,24187,0,0,1457,86689,0,0,428,8690,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,128:6:0 0,3,29:1:0 +17 1872 . G 0 . DP=25;I16=10,14,0,0,763,25437,0,0,1397,83089,0,0,425,8803,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,132:6:0 0,3,43:1:0 +17 1873 . G 0 . DP=26;I16=11,15,0,0,790,25548,0,0,1517,90289,0,0,429,8931,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,151:7:0 0,3,43:1:0 +17 1874 . G 0 . DP=27;I16=11,16,0,0,861,29013,0,0,1577,93889,0,0,430,9076,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,172:8:0 0,3,43:1:0 +17 1875 . G 0 . DP=26;I16=11,15,0,0,800,26216,0,0,1517,90289,0,0,431,9155,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,168:7:0 0,3,42:1:0 +17 1876 . C 0 . DP=26;I16=10,15,0,0,894,32714,0,0,1457,86689,0,0,432,9268,0,0;QS=3,0;MQSB=0.9171;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,171:7:0 0,3,41:1:0 +17 1877 . T 0 . DP=25;I16=9,15,0,0,848,30804,0,0,1397,83089,0,0,409,8787,0,0;QS=3,0;MQSB=0.904837;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,163:6:0 0,3,42:1:0 +17 1878 . C 0 . DP=25;I16=10,15,0,0,906,33478,0,0,1457,86689,0,0,434,9488,0,0;QS=3,0;MQSB=0.9171;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,166:7:0 0,3,40:1:0 +17 1879 . A 0 . DP=26;I16=10,16,0,0,911,32761,0,0,1517,90289,0,0,433,9543,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,191:8:0 0,3,40:1:0 +17 1880 . C 0 . DP=26;I16=10,16,0,0,790,24876,0,0,1517,90289,0,0,431,9527,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,152:8:0 0,3,31:1:0 +17 1881 . G 0 . DP=27;I16=10,15,0,0,782,25352,0,0,1500,90000,0,0,380,8288,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,144:7:0 0,3,42:1:0 +17 1882 . G 0 . DP=28;I16=12,15,0,0,937,33215,0,0,1577,93889,0,0,406,8952,0,0;QS=3,0;MQSB=0.935229;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,164:7:0 0,3,42:1:0 +17 1883 . A 0 . DP=29;I16=14,15,0,0,998,35394,0,0,1697,101089,0,0,434,9646,0,0;QS=3,0;MQSB=0.947838;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,24,180:8:0 0,3,43:1:0 +17 1884 . G 0 . DP=29;I16=14,15,0,0,1036,37926,0,0,1697,101089,0,0,437,9647,0,0;QS=3,0;MQSB=0.947838;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,24,202:8:0 0,3,42:1:0 +17 1885 . C 0 . DP=28;I16=14,13,0,0,925,32305,0,0,1577,93889,0,0,430,9560,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,182:7:0 0,3,42:1:0 +17 1886 . C 0 . DP=26;I16=13,13,0,0,826,27194,0,0,1517,90289,0,0,447,9745,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,166:8:0 0,3,32:1:0 +17 1887 . G 0 . DP=26;I16=12,13,0,0,798,26554,0,0,1500,90000,0,0,428,9212,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,185:8:0 0,3,40:1:0 +17 1888 . C 0 . DP=26;I16=13,13,0,0,901,32343,0,0,1517,90289,0,0,459,9957,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,178:8:0 0,3,39:1:0 +17 1889 . C 0 . DP=25;I16=13,11,0,0,825,29127,0,0,1397,83089,0,0,444,9612,0,0;QS=3,0;MQSB=0.950498;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,187:7:0 0,3,37:1:0 +17 1890 . C 0 . DP=25;I16=13,12,0,0,913,34029,0,0,1457,86689,0,0,471,10173,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,198:8:0 0,3,40:1:0 +17 1891 . T 0 . DP=25;I16=13,12,0,0,912,34028,0,0,1457,86689,0,0,477,10317,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,212:8:0 0,3,39:1:0 +17 1892 . G 0 . DP=25;I16=12,12,0,0,885,33149,0,0,1397,83089,0,0,458,9860,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,166:7:0 0,3,37:1:0 +17 1893 . T 0 . DP=26;I16=14,12,0,0,920,33494,0,0,1517,90289,0,0,489,10677,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,205:8:0 0,6,72:2:0 +17 1894 . G 0 . DP=26;I16=14,12,0,0,934,35048,0,0,1517,90289,0,0,495,10843,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,188:8:0 0,6,75:2:0 +17 1895 . C 0 . DP=26;I16=13,12,0,0,882,31980,0,0,1500,90000,0,0,476,10408,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,180:8:0 0,6,73:2:0 +17 1896 . C 0 . DP=26;I16=14,11,0,0,827,28179,0,0,1457,86689,0,0,482,10622,0,0;QS=3,0;MQSB=0.955682;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,154:7:0 0,6,72:2:0 +17 1897 . G 0 . DP=26;I16=13,11,0,0,763,25169,0,0,1397,83089,0,0,486,10856,0,0;QS=3,0;MQSB=0.950498;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,164:7:0 0,3,27:1:0 +17 1898 . T 0 . DP=27;I16=14,11,0,0,846,29526,0,0,1500,90000,0,0,492,11072,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,187:8:0 0,6,62:2:0 +17 1899 . G 0 . DP=27;I16=14,11,0,0,875,32007,0,0,1500,90000,0,0,497,11213,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,188:8:0 0,6,61:2:0 +17 1900 . T 0 . DP=26;I16=14,11,0,0,850,29882,0,0,1500,90000,0,0,501,11329,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,185:8:0 0,6,69:2:0 +17 1901 . A 0 . DP=27;I16=15,10,0,0,842,29298,0,0,1457,86689,0,0,505,11469,0,0;QS=3,0;MQSB=0.962269;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,190:7:0 0,6,68:2:0 +17 1902 . C 0 . DP=27;I16=15,12,0,0,912,31970,0,0,1577,93889,0,0,537,12267,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,184:8:0 0,6,60:2:0 +17 1903 . C 0 . DP=27;I16=15,12,0,0,959,34645,0,0,1577,93889,0,0,542,12462,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,201:8:0 0,6,63:2:0 +17 1904 . T 0 . DP=27;I16=16,11,0,0,1017,38757,0,0,1577,93889,0,0,548,12682,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,221:8:0 0,6,77:2:0 +17 1905 . C 0 . DP=27;I16=16,11,0,0,985,36561,0,0,1577,93889,0,0,553,12827,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,211:8:0 0,6,69:2:0 +17 1906 . T 0 . DP=27;I16=16,11,0,0,1018,39242,0,0,1577,93889,0,0,558,12998,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,207:8:0 0,6,75:2:0 +17 1907 . G 0 . DP=27;I16=15,11,0,0,935,34679,0,0,1517,90289,0,0,535,12419,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,187:7:0 0,6,68:2:0 +17 1908 . A 0 . DP=28;I16=16,12,0,0,1023,38221,0,0,1637,97489,0,0,561,13063,0,0;QS=3,0;MQSB=0.96195;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,215:8:0 0,6,67:2:0 +17 1909 . G 0 . DP=27;I16=15,12,0,0,1002,38398,0,0,1577,93889,0,0,561,12953,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,206:8:0 0,6,73:2:0 +17 1910 . C 0 . DP=27;I16=14,10,0,0,855,31251,0,0,1440,86400,0,0,502,11588,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,179:7:0 0,6,71:2:0 +17 1911 . C 0 . DP=27;I16=15,12,0,0,967,35429,0,0,1577,93889,0,0,561,12793,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,206:8:0 0,6,71:2:0 +17 1912 . C 0 . DP=27;I16=15,12,0,0,1024,39272,0,0,1577,93889,0,0,561,12743,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,217:8:0 0,6,73:2:0 +17 1913 . T 0 . DP=27;I16=15,12,0,0,1028,39768,0,0,1577,93889,0,0,561,12713,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,228:8:0 0,6,77:2:0 +17 1914 . C 0 . DP=27;I16=15,12,0,0,1010,38762,0,0,1577,93889,0,0,561,12703,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,221:8:0 0,6,75:2:0 +17 1915 . T C, 0 . DP=27;I16=14,12,1,0,974,37184,16,256,1560,93600,17,289,543,12389,18,324;QS=2.97351,0.0264901,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.958048;BQB=1;MQ0F=0 PL:DP:DV 0,34,255,48,255,255:17:1 0,24,231,24,231,231:8:0 0,6,60,6,60,60:2:0 +17 1916 . G T, 0 . DP=27;I16=14,12,1,0,991,38291,15,225,1560,93600,17,289,544,12454,17,289;QS=2.97581,0.0241935,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.958048;BQB=1;MQ0F=0 PL:DP:DV 0,35,255,48,255,255:17:1 0,24,226,24,226,226:8:0 0,6,69,6,69,69:2:0 +17 1917 . C 0 . DP=27;I16=15,12,0,0,1030,39740,0,0,1577,93889,0,0,561,12793,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,214:8:0 0,6,73:2:0 +17 1918 . A 0 . DP=27;I16=15,11,0,0,963,36201,0,0,1517,90289,0,0,542,12502,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,217:8:0 0,6,72:2:0 +17 1919 . C 0 . DP=27;I16=15,12,0,0,987,36651,0,0,1577,93889,0,0,560,12902,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,214:8:0 0,6,72:2:0 +17 1920 . A T, 0 . DP=29;I16=15,12,0,1,1007,38337,14,196,1546,91130,60,3600,538,12518,21,441;QS=2.97647,0.0235294,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.999735;BQB=1;MQ0F=0 PL:DP:DV 0,36,255,48,255,255:17:1 0,24,225,24,225,225:8:0 0,9,101,9,101,101:3:0 +17 1921 . G 0 . DP=30;I16=15,14,0,0,1059,39815,0,0,1666,98330,0,0,542,12474,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,182:7:0 0,12,132:4:0 +17 1922 . T 0 . DP=29;I16=14,14,0,0,1013,37513,0,0,1649,98041,0,0,532,12418,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,197:7:0 0,12,134:4:0 +17 1923 . G 0 . DP=28;I16=14,14,0,0,1034,38974,0,0,1606,94730,0,0,545,12629,0,0;QS=3,0;MQSB=0.999736;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,188:7:0 0,12,126:4:0 +17 1924 . C 0 . DP=27;I16=13,13,0,0,965,36587,0,0,1486,87530,0,0,521,12017,0,0;QS=3,0;MQSB=0.999671;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,183:7:0 0,12,116:4:0 +17 1925 . C 0 . DP=27;I16=14,13,0,0,987,37021,0,0,1546,91130,0,0,546,12626,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,187:7:0 0,12,124:4:0 +17 1926 . T 0 . DP=27;I16=14,13,0,0,1031,40057,0,0,1546,91130,0,0,545,12581,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,197:7:0 0,12,141:4:0 +17 1927 . T 0 . DP=27;I16=13,13,0,0,959,35773,0,0,1529,90841,0,0,538,12522,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,191:7:0 0,12,133:4:0 +17 1928 . C 0 . DP=27;I16=13,13,0,0,986,38264,0,0,1529,90841,0,0,538,12532,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,189:7:0 0,12,125:4:0 +17 1929 . T 0 . DP=27;I16=13,13,0,0,990,38630,0,0,1529,90841,0,0,538,12562,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,189:7:0 0,12,139:4:0 +17 1930 . G 0 . DP=26;I16=13,11,0,0,905,34865,0,0,1409,83641,0,0,521,12271,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,179:6:0 0,9,99:3:0 +17 1931 . C 0 . DP=27;I16=15,12,0,0,967,36293,0,0,1546,91130,0,0,540,12578,0,0;QS=3,0;MQSB=0.99881;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,165:6:0 0,12,121:4:0 +17 1932 . T 0 . DP=27;I16=14,13,0,0,998,38154,0,0,1546,91130,0,0,541,12605,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,143:5:0 0,15,146:5:0 +17 1933 . T 0 . DP=27;I16=14,13,0,0,962,35344,0,0,1546,91130,0,0,542,12602,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,142:5:0 0,15,158:5:0 +17 1934 . G 0 . DP=27;I16=13,13,0,0,987,38219,0,0,1529,90841,0,0,543,12569,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,134:5:0 0,15,143:5:0 +17 1935 . C 0 . DP=27;I16=14,12,0,0,963,36627,0,0,1529,90841,0,0,520,11930,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,162:6:0 0,15,154:5:0 +17 1936 . C 0 . DP=27;I16=14,13,0,0,1018,39406,0,0,1589,94441,0,0,547,12561,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,177:6:0 0,15,159:5:0 +17 1937 . T 0 . DP=27;I16=14,13,0,0,1036,40636,0,0,1589,94441,0,0,547,12489,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,182:6:0 0,15,170:5:0 +17 1938 . G 0 . DP=27;I16=14,13,0,0,1001,38377,0,0,1589,94441,0,0,546,12392,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,166:6:0 0,15,155:5:0 +17 1939 . T 0 . DP=27;I16=14,12,0,0,964,36430,0,0,1560,93600,0,0,525,11909,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,167:6:0 0,12,144:4:0 +17 1940 . G 0 . DP=27;I16=14,13,0,0,1003,37937,0,0,1589,94441,0,0,542,12172,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,159:6:0 0,15,155:5:0 +17 1941 . G 0 . DP=27;I16=14,13,0,0,1004,38072,0,0,1589,94441,0,0,540,12098,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,176:6:0 0,15,156:5:0 +17 1942 . C 0 . DP=27;I16=14,12,0,0,996,38790,0,0,1560,93600,0,0,516,11564,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,174:6:0 0,12,140:4:0 +17 1943 . T 0 . DP=27;I16=14,13,0,0,1044,40952,0,0,1589,94441,0,0,536,12022,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,184:6:0 0,15,167:5:0 +17 1944 . T 0 . DP=27;I16=14,13,0,0,987,37237,0,0,1589,94441,0,0,533,11971,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,175:6:0 0,15,170:5:0 +17 1945 . T 0 . DP=27;I16=14,13,0,0,993,37067,0,0,1589,94441,0,0,530,11946,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,174:6:0 0,15,171:5:0 +17 1946 . G 0 . DP=27;I16=14,13,0,0,1013,38617,0,0,1589,94441,0,0,526,11896,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,162:6:0 0,15,162:5:0 +17 1947 . A 0 . DP=26;I16=13,13,0,0,950,35522,0,0,1529,90841,0,0,522,11818,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,167:6:0 0,15,160:5:0 +17 1948 . G C, 0 . DP=27;I16=14,12,0,1,966,36912,16,256,1560,93600,29,841,493,11135,25,625;QS=2.90361,0.0963855,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.94394;BQB=1;MQ0F=0 PL:DP:DV 0,45,255,45,255,255:15:0 0,21,190,21,190,190:7:0 1,0,123,13,126,132:5:1 +17 1949 . A 0 . DP=26;I16=14,11,0,0,871,31325,0,0,1469,87241,0,0,490,11048,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,174:7:0 0,15,155:5:0 +17 1950 . A 0 . DP=27;I16=14,13,0,0,1007,38049,0,0,1589,94441,0,0,511,11559,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,205:7:0 0,18,176:6:0 +17 1951 . G 0 . DP=27;I16=14,13,0,0,960,35536,0,0,1589,94441,0,0,509,11469,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,180:7:0 0,18,181:6:0 +17 1952 . A 0 . DP=27;I16=14,12,0,0,924,33366,0,0,1529,90841,0,0,483,10779,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,184:7:0 0,18,182:6:0 +17 1953 . A 0 . DP=28;I16=15,12,0,0,925,32719,0,0,1589,94441,0,0,482,10740,0,0;QS=3,0;MQSB=0.935229;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,189:7:0 0,18,168:6:0 +17 1954 . A C, 0 . DP=29;I16=14,13,0,1,929,33219,18,324,1620,97200,29,841,475,10679,25,625;QS=2.90217,0.0978261,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.949591;BQB=1;MQ0F=0 PL:DP:DV 0,45,255,45,255,255:15:0 0,21,198,21,198,198:7:0 0,0,130,15,133,141:6:1 +17 1955 . C 0 . DP=29;I16=14,12,0,0,961,36067,0,0,1560,93600,0,0,451,10035,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,206:7:0 0,15,165:5:0 +17 1956 . C 0 . DP=29;I16=14,13,0,0,964,35402,0,0,1620,97200,0,0,475,10573,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,196:7:0 0,15,164:5:0 +17 1957 . C 0 . DP=29;I16=14,13,0,0,980,36212,0,0,1620,97200,0,0,472,10420,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,183:7:0 0,15,167:5:0 +17 1958 . C 0 . DP=29;I16=15,13,0,0,1003,37293,0,0,1649,98041,0,0,493,10825,0,0;QS=3,0;MQSB=0.942064;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,191:7:0 0,18,190:6:0 +17 1959 . T 0 . DP=29;I16=16,13,0,0,1112,43258,0,0,1709,101641,0,0,491,10593,0,0;QS=3,0;MQSB=0.940317;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,213:7:0 0,18,193:6:0 +17 1960 . T 0 . DP=30;I16=17,13,0,0,1053,37939,0,0,1769,105241,0,0,485,10339,0,0;QS=3,0;MQSB=0.938685;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,196:7:0 0,18,186:6:0 +17 1961 . C 0 . DP=30;I16=17,13,0,0,1101,41737,0,0,1769,105241,0,0,480,10122,0,0;QS=3,0;MQSB=0.938685;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,195:7:0 0,18,183:6:0 +17 1962 . T 0 . DP=29;I16=17,12,0,0,1134,44582,0,0,1709,101641,0,0,477,9941,0,0;QS=3,0;MQSB=0.931617;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,208:7:0 0,18,198:6:0 +17 1963 . G 0 . DP=28;I16=16,12,0,0,1066,41050,0,0,1649,98041,0,0,476,9794,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,192:7:0 0,18,188:6:0 +17 1964 . G 0 . DP=28;I16=16,12,0,0,970,34764,0,0,1649,98041,0,0,475,9681,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,178:7:0 0,18,169:6:0 +17 1965 . T 0 . DP=29;I16=16,12,0,0,964,34772,0,0,1649,98041,0,0,449,8977,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,196:7:0 0,18,171:6:0 +17 1966 . T 0 . DP=29;I16=16,13,0,0,1029,37027,0,0,1709,101641,0,0,474,9558,0,0;QS=3,0;MQSB=0.940317;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,191:7:0 0,18,181:6:0 +17 1967 . A 0 . DP=29;I16=16,13,0,0,1030,37234,0,0,1709,101641,0,0,474,9550,0,0;QS=3,0;MQSB=0.940317;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,187:7:0 0,18,182:6:0 +17 1968 . T 0 . DP=29;I16=16,13,0,0,1075,40173,0,0,1709,101641,0,0,474,9578,0,0;QS=3,0;MQSB=0.940317;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,195:7:0 0,18,190:6:0 +17 1969 . A 0 . DP=28;I16=16,12,0,0,992,35828,0,0,1649,98041,0,0,474,9592,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,175:6:0 0,18,186:6:0 +17 1970 . C 0 . DP=28;I16=16,12,0,0,1015,37503,0,0,1649,98041,0,0,474,9642,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,170:6:0 0,18,180:6:0 +17 1971 . A 0 . DP=29;I16=16,13,0,0,1073,40273,0,0,1709,101641,0,0,474,9728,0,0;QS=3,0;MQSB=0.940317;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,178:6:0 0,21,206:7:0 +17 1972 . T 0 . DP=30;I16=16,14,0,0,1068,38978,0,0,1769,105241,0,0,475,9851,0,0;QS=3,0;MQSB=0.946202;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,176:6:0 0,21,203:7:0 +17 1973 . A 0 . DP=30;I16=16,13,0,0,1046,38070,0,0,1740,104400,0,0,452,9388,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,172:6:0 0,18,196:6:0 +17 1974 . A 0 . DP=29;I16=16,13,0,0,1086,41474,0,0,1709,101641,0,0,477,10065,0,0;QS=3,0;MQSB=0.940317;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,157:5:0 0,21,214:7:0 +17 1975 . G 0 . DP=28;I16=16,12,0,0,1067,41171,0,0,1649,98041,0,0,478,10156,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,133:4:0 0,21,195:7:0 +17 1976 . A 0 . DP=28;I16=16,12,0,0,981,34839,0,0,1649,98041,0,0,478,10234,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,125:4:0 0,21,199:7:0 +17 1977 . C 0 . DP=28;I16=16,12,0,0,1009,37471,0,0,1649,98041,0,0,477,10297,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,132:4:0 0,21,194:7:0 +17 1978 . A 0 . DP=28;I16=16,12,0,0,1082,42132,0,0,1649,98041,0,0,476,10394,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,144:4:0 0,21,220:7:0 +17 1979 . G 0 . DP=28;I16=16,11,0,0,1019,38927,0,0,1589,94441,0,0,454,10064,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,122:4:0 0,21,208:7:0 +17 1980 . C 0 . DP=27;I16=16,10,0,0,932,34456,0,0,1529,90841,0,0,452,10114,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,107:3:0 0,21,197:7:0 +17 1981 . C 0 . DP=28;I16=16,12,0,0,998,36510,0,0,1649,98041,0,0,469,10479,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,101:3:0 0,24,219:8:0 +17 1982 . A 0 . DP=29;I16=16,12,0,0,1035,38815,0,0,1649,98041,0,0,472,10548,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,110:3:0 0,27,254:9:0 +17 1983 . G 0 . DP=28;I16=16,12,0,0,1048,40322,0,0,1649,98041,0,0,477,10599,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,96:3:0 0,27,249:9:0 +17 1984 . A 0 . DP=27;I16=16,11,0,0,1024,39232,0,0,1589,94441,0,0,482,10632,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,70:2:0 0,27,255:9:0 +17 1985 . G 0 . DP=27;I16=16,11,0,0,1009,38449,0,0,1589,94441,0,0,487,10695,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,66:2:0 0,27,231:9:0 +17 1986 . A 0 . DP=27;I16=16,10,0,0,926,33696,0,0,1560,93600,0,0,466,10112,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,76:2:0 0,24,223:8:0 +17 1987 . A 0 . DP=28;I16=17,11,0,0,1034,39088,0,0,1649,98041,0,0,495,10807,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,78:2:0 0,27,247:9:0 +17 1988 . G 0 . DP=28;I16=17,11,0,0,1050,39980,0,0,1649,98041,0,0,499,10855,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,63:2:0 0,27,239:9:0 +17 1989 . G 0 . DP=28;I16=17,10,0,0,994,37610,0,0,1589,94441,0,0,493,10801,0,0;QS=3,0;MQSB=0.912952;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,73:2:0 0,27,237:9:0 +17 1990 . G T, 0 . DP=28;I16=17,9,0,1,965,36359,33,1089,1560,93600,29,841,472,10250,25,625;QS=2.90675,0.0932476,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.912952;BQB=1;MQ0F=0 PL:DP:DV 0,48,255,48,255,255:16:0 0,6,71,6,71,71:2:0 2,0,195,26,198,215:9:1 +17 1991 . A 0 . DP=28;I16=17,11,0,0,1017,38203,0,0,1649,98041,0,0,507,10975,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,60:2:0 0,27,250:9:0 +17 1992 . G 0 . DP=28;I16=17,11,0,0,1028,38852,0,0,1649,98041,0,0,509,11039,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,62:2:0 0,27,231:9:0 +17 1993 . T 0 . DP=28;I16=17,11,0,0,1015,37325,0,0,1649,98041,0,0,511,11131,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,59:2:0 0,27,243:9:0 +17 1994 . T 0 . DP=27;I16=16,11,0,0,942,33698,0,0,1589,94441,0,0,514,11250,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,54:2:0 0,24,216:8:0 +17 1995 . G 0 . DP=28;I16=16,11,0,0,960,35432,0,0,1620,97200,0,0,492,10770,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,66:2:0 0,21,188:7:0 +17 1996 . C 0 . DP=29;I16=17,12,0,0,1022,37426,0,0,1709,101641,0,0,519,11469,0,0;QS=3,0;MQSB=0.931617;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,64:2:0 0,24,192:8:0 +17 1997 . C 0 . DP=29;I16=17,11,0,0,934,32858,0,0,1649,98041,0,0,520,11524,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,70:2:0 0,24,193:8:0 +17 1998 . C 0 . DP=29;I16=17,12,0,0,1027,37843,0,0,1709,101641,0,0,522,11562,0,0;QS=3,0;MQSB=0.931617;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,69:2:0 0,24,222:8:0 +17 1999 . A 0 . DP=28;I16=17,11,0,0,1073,41493,0,0,1649,98041,0,0,525,11627,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,72:2:0 0,21,206:7:0 +17 2000 . G 0 . DP=28;I16=16,11,0,0,1036,40576,0,0,1589,94441,0,0,511,11395,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,72:2:0 0,18,168:6:0 +17 2001 . G 0 . DP=28;I16=15,11,0,0,955,35661,0,0,1529,90841,0,0,489,10853,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,62:2:0 0,18,172:6:0 +17 2002 . G 0 . DP=28;I16=17,10,0,0,907,32227,0,0,1620,97200,0,0,519,11663,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,53:2:0 0,18,163:6:0 +17 2003 . T 0 . DP=28;I16=17,11,0,0,920,31866,0,0,1649,98041,0,0,541,12163,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,49:2:0 0,21,190:7:0 +17 2004 . G 0 . DP=27;I16=16,10,0,0,970,36928,0,0,1560,93600,0,0,530,12110,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,57:2:0 0,18,178:6:0 +17 2005 . G 0 . DP=27;I16=16,10,0,0,868,30936,0,0,1560,93600,0,0,536,12370,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,59:2:0 0,18,153:6:0 +17 2006 . C 0 . DP=27;I16=16,10,0,0,968,37046,0,0,1560,93600,0,0,541,12605,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,73:2:0 0,18,166:6:0 +17 2007 . A 0 . DP=27;I16=16,11,0,0,1000,37396,0,0,1589,94441,0,0,556,12882,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,76:2:0 0,21,193:7:0 +17 2008 . C 0 . DP=26;I16=16,10,0,0,964,36892,0,0,1529,90841,0,0,555,12833,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,73:2:0 0,21,183:7:0 +17 2009 . A 0 . DP=26;I16=16,10,0,0,997,38955,0,0,1529,90841,0,0,554,12802,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,74:2:0 0,21,210:7:0 +17 2010 . G 0 . DP=26;I16=16,9,0,0,936,36208,0,0,1500,90000,0,0,542,12640,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,73:2:0 0,18,169:6:0 +17 2011 . C 0 . DP=26;I16=16,9,0,0,966,37960,0,0,1500,90000,0,0,541,12617,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,74:2:0 0,18,175:6:0 +17 2012 . A 0 . DP=27;I16=16,11,0,0,956,35018,0,0,1589,94441,0,0,548,12676,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,74:2:0 0,21,189:7:0 +17 2013 . C 0 . DP=27;I16=15,10,0,0,876,31370,0,0,1500,90000,0,0,514,11950,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,69:2:0 0,18,160:6:0 +17 2014 . G 0 . DP=27;I16=17,10,0,0,903,31239,0,0,1589,94441,0,0,545,12591,0,0;QS=3,0;MQSB=0.912952;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,80:3:0 0,18,160:6:0 +17 2015 . T 0 . DP=27;I16=17,10,0,0,999,37507,0,0,1589,94441,0,0,545,12577,0,0;QS=3,0;MQSB=0.912952;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,95:3:0 0,18,178:6:0 +17 2016 . T 0 . DP=27;I16=17,10,0,0,971,35649,0,0,1589,94441,0,0,545,12583,0,0;QS=3,0;MQSB=0.912952;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,93:3:0 0,18,178:6:0 +17 2017 . G 0 . DP=28;I16=17,11,0,0,1013,37849,0,0,1649,98041,0,0,545,12609,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,9,91:3:0 0,18,172:6:0 +17 2018 . C 0 . DP=28;I16=17,11,0,0,1060,41414,0,0,1649,98041,0,0,546,12656,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,9,97:3:0 0,18,169:6:0 +17 2019 . T 0 . DP=28;I16=17,11,0,0,1083,42253,0,0,1649,98041,0,0,547,12725,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,9,106:3:0 0,18,187:6:0 +17 2020 . G 0 . DP=29;I16=18,11,0,0,1095,42063,0,0,1678,98882,0,0,548,12816,0,0;QS=3,0;MQSB=0.987702;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,9,85:3:0 0,18,175:6:0 +17 2021 . C 0 . DP=29;I16=18,11,0,0,1081,41535,0,0,1709,101641,0,0,551,12877,0,0;QS=3,0;MQSB=0.969907;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,97:3:0 0,15,167:5:0 +17 2022 . C 0 . DP=30;I16=19,11,0,0,1115,42003,0,0,1769,105241,0,0,555,12907,0,0;QS=3,0;MQSB=0.972375;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,92:3:0 0,18,177:6:0 +17 2023 . A 0 . DP=30;I16=19,10,0,0,1063,39991,0,0,1709,101641,0,0,549,12837,0,0;QS=3,0;MQSB=0.974027;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,9,96:3:0 0,18,186:6:0 +17 2024 . G 0 . DP=32;I16=20,12,0,0,1168,43872,0,0,1889,112441,0,0,564,12982,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,92:3:0 0,24,203:8:0 +17 2025 . T 0 . DP=32;I16=20,12,0,0,1150,42122,0,0,1889,112441,0,0,569,12981,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,87:3:0 0,24,226:8:0 +17 2026 . T 0 . DP=32;I16=20,12,0,0,1130,40724,0,0,1889,112441,0,0,572,12908,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,94:3:0 0,24,208:8:0 +17 2027 . A 0 . DP=32;I16=19,12,0,0,1121,40871,0,0,1829,108841,0,0,550,12240,0,0;QS=3,0;MQSB=0.970829;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,84:3:0 0,21,207:7:0 +17 2028 . C 0 . DP=32;I16=20,12,0,0,1242,48548,0,0,1889,112441,0,0,577,12803,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,94:3:0 0,24,228:8:0 +17 2029 . T 0 . DP=32;I16=20,12,0,0,1229,47605,0,0,1889,112441,0,0,578,12724,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,102:3:0 0,24,236:8:0 +17 2030 . G 0 . DP=32;I16=20,12,0,0,1222,47140,0,0,1889,112441,0,0,579,12679,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,93:3:0 0,24,216:8:0 +17 2031 . C 0 . DP=31;I16=19,12,0,0,1150,43656,0,0,1829,108841,0,0,581,12667,0,0;QS=3,0;MQSB=0.970829;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,9,96:3:0 0,24,204:8:0 +17 2032 . C 0 . DP=31;I16=19,12,0,0,1157,44035,0,0,1829,108841,0,0,583,12687,0,0;QS=3,0;MQSB=0.970829;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,9,90:3:0 0,24,210:8:0 +17 2033 . A 0 . DP=30;I16=19,11,0,0,1091,40223,0,0,1769,105241,0,0,585,12689,0,0;QS=3,0;MQSB=0.972375;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,9,93:3:0 0,21,203:7:0 +17 2034 . T 0 . DP=30;I16=19,11,0,0,1104,41498,0,0,1769,105241,0,0,587,12723,0,0;QS=3,0;MQSB=0.972375;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,9,91:3:0 0,21,208:7:0 +17 2035 . T 0 . DP=29;I16=18,11,0,0,1084,41024,0,0,1709,101641,0,0,589,12739,0,0;QS=3,0;MQSB=0.969907;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,69:2:0 0,21,211:7:0 +17 2036 . T 0 . DP=29;I16=18,11,0,0,1080,40612,0,0,1709,101641,0,0,591,12787,0,0;QS=3,0;MQSB=0.969907;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,67:2:0 0,21,216:7:0 +17 2037 . T 0 . DP=29;I16=18,11,0,0,1082,40956,0,0,1709,101641,0,0,592,12818,0,0;QS=3,0;MQSB=0.969907;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,69:2:0 0,21,217:7:0 +17 2038 . C 0 . DP=29;I16=18,11,0,0,1117,43573,0,0,1709,101641,0,0,592,12832,0,0;QS=3,0;MQSB=0.969907;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,69:2:0 0,21,211:7:0 +17 2039 . A 0 . DP=29;I16=18,11,0,0,1067,39581,0,0,1709,101641,0,0,592,12878,0,0;QS=3,0;MQSB=0.969907;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,72:2:0 0,21,212:7:0 +17 2040 . C 0 . DP=29;I16=18,11,0,0,1077,40469,0,0,1709,101641,0,0,590,12856,0,0;QS=3,0;MQSB=0.969907;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,69:2:0 0,21,196:7:0 +17 2041 . G A, 0 . DP=31;I16=6,5,12,7,389,14023,721,28149,660,39600,1109,65641,235,5607,353,7259;QS=0.917304,2.0827,0;VDB=0.816435;SGB=-4.18892;RPB=0.88473;MQB=0.972375;MQSB=0.968257;BQB=0.311275;MQ0F=0 PL:DP:DV 229,0,212,255,245,255:21:11 32,0,24,35,27,59:2:1 223,21,0,223,21,223:7:7 +17 2042 . G 0 . DP=32;I16=18,14,0,0,1189,45617,0,0,1889,112441,0,0,588,12910,0,0;QS=3,0;MQSB=0.965264;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,9,86:3:0 0,21,206:7:0 +17 2043 . G 0 . DP=32;I16=17,14,0,0,1115,41585,0,0,1829,108841,0,0,581,12891,0,0;QS=3,0;MQSB=0.962133;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,90:3:0 0,21,197:7:0 +17 2044 . C 0 . DP=32;I16=18,14,0,0,1213,47029,0,0,1889,112441,0,0,588,13006,0,0;QS=3,0;MQSB=0.965264;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,9,85:3:0 0,21,207:7:0 +17 2045 . A 0 . DP=32;I16=18,14,0,0,1181,44527,0,0,1889,112441,0,0,588,13108,0,0;QS=3,0;MQSB=0.965264;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,9,83:3:0 0,21,213:7:0 +17 2046 . T 0 . DP=32;I16=18,14,0,0,1197,45135,0,0,1889,112441,0,0,587,13195,0,0;QS=3,0;MQSB=0.965264;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,9,103:3:0 0,21,216:7:0 +17 2047 . G 0 . DP=34;I16=17,16,0,0,1248,47798,0,0,1949,116041,0,0,557,12491,0,0;QS=3,0;MQSB=0.959328;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,9,88:3:0 0,18,195:6:0 +17 2048 . A 0 . DP=34;I16=18,16,0,0,1230,45184,0,0,2009,119641,0,0,578,13022,0,0;QS=3,0;MQSB=0.962621;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,9,87:3:0 0,21,206:7:0 +17 2049 . A 0 . DP=33;I16=17,16,0,0,1207,44567,0,0,1949,116041,0,0,575,12963,0,0;QS=3,0;MQSB=0.959328;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,6,74:2:0 0,21,208:7:0 +17 2050 . A 0 . DP=33;I16=16,16,0,0,1169,43313,0,0,1889,112441,0,0,545,12211,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,6,77:2:0 0,18,188:6:0 +17 2051 . T 0 . DP=31;I16=16,15,0,0,1134,42164,0,0,1829,108841,0,0,567,12737,0,0;QS=3,0;MQSB=0.957006;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,6,69:2:0 0,18,170:6:0 +17 2052 . G 0 . DP=31;I16=16,15,0,0,1180,45546,0,0,1829,108841,0,0,564,12664,0,0;QS=3,0;MQSB=0.957006;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,6,74:2:0 0,18,175:6:0 +17 2053 . G T, 0 . DP=31;I16=15,15,0,1,1126,42672,23,529,1769,105241,60,3600,537,11991,25,625;QS=2.97307,0.0269321,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.951229;BQB=1;MQ0F=0 PL:DP:DV 0,46,255,66,255,255:23:1 0,6,71,6,71,71:2:0 0,18,180,18,180,180:6:0 +17 2054 . A 0 . DP=30;I16=15,15,0,0,1123,43027,0,0,1769,105241,0,0,562,12592,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,6,78:2:0 0,18,171:6:0 +17 2055 . G 0 . DP=30;I16=15,15,0,0,1156,45206,0,0,1769,105241,0,0,562,12592,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,6,66:2:0 0,18,168:6:0 +17 2056 . A 0 . DP=30;I16=15,15,0,0,1124,42416,0,0,1769,105241,0,0,560,12518,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,6,71:2:0 0,18,179:6:0 +17 2057 . T 0 . DP=30;I16=15,15,0,0,1094,40082,0,0,1769,105241,0,0,556,12374,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,6,72:2:0 0,18,178:6:0 +17 2058 . A 0 . DP=29;I16=14,15,0,0,1035,37517,0,0,1709,101641,0,0,552,12212,0,0;QS=3,0;MQSB=0.947838;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,6,57:2:0 0,18,179:6:0 +17 2059 . A 0 . DP=29;I16=14,15,0,0,1063,39615,0,0,1709,101641,0,0,548,12082,0,0;QS=3,0;MQSB=0.947838;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,6,66:2:0 0,18,188:6:0 +17 2060 . C 0 . DP=28;I16=12,15,0,0,1015,39057,0,0,1589,94441,0,0,523,11499,0,0;QS=3,0;MQSB=0.935229;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,62:2:0 0,15,143:5:0 +17 2061 . A 0 . DP=27;I16=12,14,0,0,950,35084,0,0,1529,90841,0,0,501,11073,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,3,41:1:0 0,15,163:5:0 +17 2062 . A 0 . DP=26;I16=11,15,0,0,973,37349,0,0,1529,90841,0,0,519,11425,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,57:2:0 0,15,164:5:0 +17 2063 . C 0 . DP=26;I16=11,15,0,0,1017,40149,0,0,1529,90841,0,0,517,11405,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,74:2:0 0,15,158:5:0 +17 2064 . A 0 . DP=26;I16=11,15,0,0,1002,38980,0,0,1529,90841,0,0,515,11413,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,75:2:0 0,15,164:5:0 +17 2065 . G 0 . DP=26;I16=12,14,0,0,1030,41232,0,0,1529,90841,0,0,514,11448,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,78:2:0 0,18,167:6:0 +17 2066 . G 0 . DP=26;I16=12,14,0,0,973,37055,0,0,1529,90841,0,0,514,11510,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,75:2:0 0,18,152:6:0 +17 2067 . A 0 . DP=26;I16=12,14,0,0,1005,39095,0,0,1529,90841,0,0,512,11498,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,69:2:0 0,18,187:6:0 +17 2068 . G 0 . DP=26;I16=12,14,0,0,993,39005,0,0,1529,90841,0,0,509,11459,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,53:2:0 0,18,167:6:0 +17 2069 . C 0 . DP=26;I16=12,14,0,0,873,29879,0,0,1529,90841,0,0,506,11442,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,59:2:0 0,18,156:6:0 +17 2070 . G 0 . DP=27;I16=13,14,0,0,932,33090,0,0,1589,94441,0,0,502,11398,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,62:2:0 0,18,145:6:0 +17 2071 . A 0 . DP=27;I16=13,14,0,0,946,33884,0,0,1589,94441,0,0,498,11330,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,53:2:0 0,18,177:6:0 +17 2072 . C 0 . DP=25;I16=13,12,0,0,897,32897,0,0,1469,87241,0,0,496,11288,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,59:2:0 0,15,128:5:0 +17 2073 . C 0 . DP=26;I16=14,12,0,0,874,30184,0,0,1529,90841,0,0,492,11168,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,53:2:0 0,15,133:5:0 +17 2074 . G 0 . DP=26;I16=13,12,0,0,835,29219,0,0,1469,87241,0,0,463,10395,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,67:2:0 0,12,83:4:0 +17 2075 . C 0 . DP=27;I16=15,12,0,0,989,37027,0,0,1589,94441,0,0,484,10896,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,69:2:0 0,15,115:5:0 +17 2076 . A 0 . DP=27;I16=14,12,0,0,929,33551,0,0,1529,90841,0,0,470,10676,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,76:2:0 0,12,114:4:0 +17 2077 . C 0 . DP=27;I16=15,12,0,0,990,37252,0,0,1589,94441,0,0,478,10724,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,65:2:0 0,15,125:5:0 +17 2078 . A 0 . DP=27;I16=15,12,0,0,1023,39089,0,0,1589,94441,0,0,475,10677,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,72:2:0 0,15,148:5:0 +17 2079 . G 0 . DP=28;I16=15,13,0,0,1042,39694,0,0,1649,98041,0,0,471,10605,0,0;QS=3,0;MQSB=0.956162;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,6,72:2:0 0,15,133:5:0 +17 2080 . G 0 . DP=28;I16=14,13,0,0,968,35328,0,0,1589,94441,0,0,453,10333,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,6,67:2:0 0,12,108:4:0 +17 2081 . C 0 . DP=26;I16=14,12,0,0,937,35303,0,0,1529,90841,0,0,467,10535,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,63:2:0 0,15,110:5:0 +17 2082 . T 0 . DP=24;I16=12,12,0,0,901,34287,0,0,1409,83641,0,0,468,10532,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,71:2:0 0,12,112:4:0 +17 2083 . G 0 . DP=24;I16=12,12,0,0,887,33597,0,0,1409,83641,0,0,469,10547,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,68:2:0 0,12,113:4:0 +17 2084 . C 0 . DP=25;I16=13,12,0,0,938,35868,0,0,1469,87241,0,0,470,10580,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,61:2:0 0,12,115:4:0 +17 2085 . T 0 . DP=25;I16=13,12,0,0,932,35282,0,0,1469,87241,0,0,472,10632,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,64:2:0 0,12,130:4:0 +17 2086 . G 0 . DP=25;I16=13,12,0,0,932,35400,0,0,1469,87241,0,0,474,10704,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,61:2:0 0,12,129:4:0 +17 2087 . A 0 . DP=24;I16=12,12,0,0,903,34391,0,0,1409,83641,0,0,476,10746,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,66:2:0 0,12,126:4:0 +17 2088 . G 0 . DP=24;I16=12,12,0,0,880,33116,0,0,1409,83641,0,0,478,10808,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,70:2:0 0,12,121:4:0 +17 2089 . C 0 . DP=25;I16=13,12,0,0,817,27419,0,0,1469,87241,0,0,480,10890,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,64:2:0 0,15,138:5:0 +17 2090 . G 0 . DP=25;I16=12,12,0,0,802,27940,0,0,1409,83641,0,0,457,10319,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,63:2:0 0,12,99:4:0 +17 2091 . C 0 . DP=25;I16=12,12,0,0,800,27346,0,0,1440,86400,0,0,458,10346,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,61:2:0 0,15,125:5:0 +17 2092 . G 0 . DP=26;I16=13,12,0,0,838,29188,0,0,1469,87241,0,0,461,10487,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,64:2:0 0,18,133:6:0 +17 2093 . T G, 0 . DP=26;I16=13,12,1,0,905,33415,17,289,1500,90000,29,841,459,10371,25,625;QS=2.97424,0.0257576,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.953497;BQB=1;MQ0F=0 PL:DP:DV 0,36,255,51,255,255:18:1 0,6,67,6,67,67:2:0 0,18,153,18,153,153:6:0 +17 2094 . C 0 . DP=26;I16=14,12,0,0,949,35501,0,0,1529,90841,0,0,485,11047,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,69:2:0 0,18,142:6:0 +17 2095 . A 0 . DP=25;I16=14,11,0,0,879,31219,0,0,1469,87241,0,0,487,11123,0,0;QS=3,0;MQSB=0.955682;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,72:2:0 0,18,154:6:0 +17 2096 . C 0 . DP=24;I16=13,11,0,0,878,32734,0,0,1409,83641,0,0,487,11073,0,0;QS=3,0;MQSB=0.950498;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,65:2:0 0,18,161:6:0 +17 2097 . A 0 . DP=24;I16=13,11,0,0,849,30671,0,0,1409,83641,0,0,487,11047,0,0;QS=3,0;MQSB=0.950498;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,56:2:0 0,18,172:6:0 +17 2098 . C 0 . DP=24;I16=13,11,0,0,781,26113,0,0,1409,83641,0,0,486,10996,0,0;QS=3,0;MQSB=0.950498;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,58:2:0 0,18,139:6:0 +17 2099 . G 0 . DP=23;I16=12,10,0,0,719,25109,0,0,1289,76441,0,0,460,10294,0,0;QS=3,0;MQSB=0.947103;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,3,24:1:0 0,18,129:6:0 +17 2100 . C 0 . DP=25;I16=13,11,0,0,873,32759,0,0,1409,83641,0,0,457,10141,0,0;QS=3,0;MQSB=0.950498;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,87:3:0 0,18,160:6:0 +17 2101 . A 0 . DP=25;I16=12,12,0,0,907,34671,0,0,1440,86400,0,0,455,9965,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,135:4:0 0,18,161:6:0 +17 2102 . G 0 . DP=25;I16=13,12,0,0,930,35596,0,0,1469,87241,0,0,478,10442,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,118:4:0 0,18,151:6:0 +17 2103 . C 0 . DP=25;I16=11,12,0,0,842,31630,0,0,1380,82800,0,0,432,9336,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,106:4:0 0,15,146:5:0 +17 2104 . C 0 . DP=24;I16=12,12,0,0,869,32463,0,0,1409,83641,0,0,454,9810,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,126:4:0 0,15,147:5:0 +17 2105 . A 0 . DP=25;I16=11,12,0,0,836,30696,0,0,1380,82800,0,0,429,9201,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,138:4:0 0,15,130:5:0 +17 2106 . T 0 . DP=25;I16=12,13,0,0,897,33087,0,0,1469,87241,0,0,473,10211,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,129:4:0 0,15,146:5:0 +17 2107 . C 0 . DP=25;I16=11,12,0,0,783,27185,0,0,1380,82800,0,0,425,9113,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,100:3:0 0,15,133:5:0 +17 2108 . G 0 . DP=25;I16=11,13,0,0,829,29703,0,0,1440,86400,0,0,448,9730,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,122:4:0 0,15,111:5:0 +17 2109 . C 0 . DP=25;I16=11,13,0,0,781,26717,0,0,1440,86400,0,0,446,9746,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,109:4:0 0,15,125:5:0 +17 2110 . G 0 . DP=25;I16=12,12,0,0,804,28134,0,0,1440,86400,0,0,418,9110,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,92:3:0 0,15,117:5:0 +17 2111 . C 0 . DP=25;I16=12,13,0,0,925,35081,0,0,1500,90000,0,0,441,9747,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,134:4:0 0,15,140:5:0 +17 2112 . A 0 . DP=24;I16=12,12,0,0,885,33445,0,0,1440,86400,0,0,440,9782,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,129:4:0 0,15,140:5:0 +17 2113 . G 0 . DP=24;I16=12,12,0,0,871,32641,0,0,1440,86400,0,0,439,9839,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,128:4:0 0,15,134:5:0 +17 2114 . C 0 . DP=24;I16=12,11,0,0,844,32052,0,0,1380,82800,0,0,413,9293,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,103:3:0 0,15,126:5:0 +17 2115 . T 0 . DP=23;I16=11,11,0,0,821,30869,0,0,1320,79200,0,0,412,9342,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,78:2:0 0,15,143:5:0 +17 2116 . C 0 . DP=23;I16=11,12,0,0,890,34892,0,0,1380,82800,0,0,435,9985,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,102:3:0 0,15,152:5:0 +17 2117 . A 0 . DP=23;I16=11,11,0,0,833,32121,0,0,1320,79200,0,0,432,9924,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,118:3:0 0,15,156:5:0 +17 2118 . G 0 . DP=23;I16=12,11,0,0,842,31502,0,0,1380,82800,0,0,429,9835,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,125:4:0 0,15,147:5:0 +17 2119 . G 0 . DP=23;I16=12,11,0,0,823,30553,0,0,1380,82800,0,0,426,9768,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,135:4:0 0,15,137:5:0 +17 2120 . G 0 . DP=24;I16=13,11,0,0,864,32028,0,0,1440,86400,0,0,423,9723,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,137:4:0 0,15,140:5:0 +17 2121 . A 0 . DP=22;I16=11,10,0,0,734,26712,0,0,1260,75600,0,0,398,9074,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,135:4:0 0,12,122:4:0 +17 2122 . T 0 . DP=22;I16=11,10,0,0,752,27278,0,0,1260,75600,0,0,396,8972,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,136:4:0 0,12,123:4:0 +17 2123 . A 0 . DP=22;I16=12,10,0,0,758,27024,0,0,1320,79200,0,0,419,9519,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,120:4:0 0,15,137:5:0 +17 2124 . T 0 . DP=22;I16=12,10,0,0,789,28741,0,0,1320,79200,0,0,417,9465,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,128:4:0 0,15,136:5:0 +17 2125 . T 0 . DP=20;I16=11,8,0,0,696,25704,0,0,1140,68400,0,0,401,9177,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,106:3:0 0,9,93:3:0 +17 2126 . A 0 . DP=20;I16=11,9,0,0,717,25979,0,0,1200,72000,0,0,415,9319,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,133:4:0 0,9,95:3:0 +17 2127 . C 0 . DP=21;I16=11,10,0,0,706,24426,0,0,1260,75600,0,0,413,9221,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,107:4:0 0,9,95:3:0 +17 2128 . G 0 . DP=21;I16=11,10,0,0,677,22633,0,0,1260,75600,0,0,411,9091,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,116:4:0 0,9,72:3:0 +17 2129 . T 0 . DP=21;I16=11,10,0,0,782,29386,0,0,1260,75600,0,0,409,8981,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,140:4:0 0,9,83:3:0 +17 2130 . G 0 . DP=21;I16=11,10,0,0,766,28562,0,0,1260,75600,0,0,407,8891,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,135:4:0 0,9,87:3:0 +17 2131 . T 0 . DP=21;I16=11,10,0,0,732,26216,0,0,1260,75600,0,0,405,8821,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,136:4:0 0,9,79:3:0 +17 2132 . A 0 . DP=21;I16=11,10,0,0,743,26733,0,0,1260,75600,0,0,403,8771,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,135:4:0 0,9,88:3:0 +17 2133 . A 0 . DP=21;I16=11,10,0,0,787,29651,0,0,1260,75600,0,0,401,8741,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,141:4:0 0,9,96:3:0 +17 2134 . C 0 . DP=21;I16=11,10,0,0,804,31100,0,0,1260,75600,0,0,399,8731,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,138:4:0 0,9,86:3:0 +17 2135 . T 0 . DP=22;I16=11,11,0,0,831,32197,0,0,1320,79200,0,0,397,8741,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,153:4:0 0,12,119:4:0 +17 2136 . C 0 . DP=22;I16=11,11,0,0,760,26892,0,0,1320,79200,0,0,395,8721,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,124:4:0 0,12,127:4:0 +17 2137 . G 0 . DP=22;I16=11,11,0,0,745,26047,0,0,1320,79200,0,0,393,8721,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,121:4:0 0,12,102:4:0 +17 2138 . A 0 . DP=22;I16=11,11,0,0,816,30934,0,0,1320,79200,0,0,391,8741,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,128:4:0 0,12,139:4:0 +17 2139 . C 0 . DP=22;I16=11,11,0,0,839,32237,0,0,1320,79200,0,0,389,8781,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,138:4:0 0,12,125:4:0 +17 2140 . A 0 . DP=22;I16=11,11,0,0,826,31300,0,0,1320,79200,0,0,387,8841,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,140:4:0 0,12,138:4:0 +17 2141 . T 0 . DP=21;I16=11,10,0,0,792,30156,0,0,1260,75600,0,0,385,8871,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,137:4:0 0,12,137:4:0 +17 2142 . G 0 . DP=19;I16=11,8,0,0,724,27784,0,0,1140,68400,0,0,385,8919,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,113:3:0 0,12,129:4:0 +17 2143 . T 0 . DP=19;I16=11,8,0,0,650,23454,0,0,1140,68400,0,0,384,8932,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,113:3:0 0,12,120:4:0 +17 2144 . C 0 . DP=19;I16=11,8,0,0,739,29003,0,0,1140,68400,0,0,383,8959,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,108:3:0 0,12,125:4:0 +17 2145 . A 0 . DP=20;I16=12,8,0,0,760,29304,0,0,1200,72000,0,0,381,8951,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,133:4:0 0,12,139:4:0 +17 2146 . G 0 . DP=20;I16=12,8,0,0,745,28105,0,0,1200,72000,0,0,379,8909,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,139:4:0 0,12,127:4:0 +17 2147 . C 0 . DP=20;I16=13,6,0,0,674,24296,0,0,1140,68400,0,0,379,8881,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,127:4:0 0,12,130:4:0 +17 2148 . G 0 . DP=20;I16=12,7,0,0,630,21274,0,0,1140,68400,0,0,365,8537,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,250:11:0 0,12,112:4:0 0,12,120:4:0 +17 2149 . A 0 . DP=20;I16=12,7,0,0,702,26212,0,0,1140,68400,0,0,367,8529,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,138:4:0 0,12,127:4:0 +17 2150 . T 0 . DP=20;I16=13,7,0,0,675,23943,0,0,1200,72000,0,0,383,8713,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,247:11:0 0,12,138:4:0 0,15,139:5:0 +17 2151 . T 0 . DP=20;I16=13,7,0,0,690,24274,0,0,1200,72000,0,0,383,8661,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,251:11:0 0,12,133:4:0 0,15,142:5:0 +17 2152 . G 0 . DP=20;I16=13,7,0,0,693,24713,0,0,1200,72000,0,0,383,8629,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,131:4:0 0,15,146:5:0 +17 2153 . T 0 . DP=19;I16=13,6,0,0,671,24571,0,0,1140,68400,0,0,383,8565,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,230:10:0 0,12,134:4:0 0,15,162:5:0 +17 2154 . C 0 . DP=19;I16=13,6,0,0,703,26955,0,0,1140,68400,0,0,382,8468,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,251:10:0 0,12,131:4:0 0,15,159:5:0 +17 2155 . A 0 . DP=19;I16=13,6,0,0,693,25727,0,0,1140,68400,0,0,381,8389,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,245:10:0 0,12,135:4:0 0,15,156:5:0 +17 2156 . C 0 . DP=19;I16=13,6,0,0,702,26214,0,0,1140,68400,0,0,380,8328,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,125:4:0 0,15,154:5:0 +17 2157 . A 0 . DP=19;I16=13,6,0,0,722,28058,0,0,1140,68400,0,0,379,8285,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,12,141:4:0 0,15,173:5:0 +17 2158 . G 0 . DP=19;I16=13,6,0,0,713,27567,0,0,1140,68400,0,0,378,8260,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,136:4:0 0,15,144:5:0 +17 2159 . G 0 . DP=19;I16=12,6,0,0,662,24744,0,0,1080,64800,0,0,366,8104,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,247:9:0 0,12,126:4:0 0,15,153:5:0 +17 2160 . C 0 . DP=19;I16=12,6,0,0,651,24005,0,0,1080,64800,0,0,364,8038,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,12,119:4:0 0,15,154:5:0 +17 2161 . A 0 . DP=19;I16=13,6,0,0,695,25883,0,0,1140,68400,0,0,369,8005,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,12,121:4:0 0,15,164:5:0 +17 2162 . C 0 . DP=20;I16=13,7,0,0,742,27834,0,0,1200,72000,0,0,365,7911,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,127:4:0 0,15,155:5:0 +17 2163 . T 0 . DP=20;I16=13,7,0,0,763,29517,0,0,1200,72000,0,0,362,7838,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,131:4:0 0,15,175:5:0 +17 2164 . G 0 . DP=20;I16=13,7,0,0,715,26301,0,0,1200,72000,0,0,359,7787,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,116:4:0 0,15,156:5:0 +17 2165 . C 0 . DP=20;I16=13,7,0,0,753,28781,0,0,1200,72000,0,0,355,7709,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,136:4:0 0,15,151:5:0 +17 2166 . T 0 . DP=19;I16=12,7,0,0,711,27211,0,0,1140,68400,0,0,352,7654,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,142:4:0 0,12,140:4:0 +17 2167 . A 0 . DP=19;I16=12,6,0,0,650,23760,0,0,1080,64800,0,0,327,7137,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,12,133:4:0 0,9,111:3:0 +17 2168 . C 0 . DP=19;I16=12,7,0,0,685,25039,0,0,1140,68400,0,0,345,7561,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,130:4:0 0,12,124:4:0 +17 2169 . T 0 . DP=19;I16=12,7,0,0,702,26940,0,0,1140,68400,0,0,341,7525,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,140:4:0 0,12,142:4:0 +17 2170 . C 0 . DP=18;I16=11,7,0,0,665,24861,0,0,1080,64800,0,0,338,7512,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,132:4:0 0,12,135:4:0 +17 2171 . C 0 . DP=20;I16=11,9,0,0,750,28368,0,0,1200,72000,0,0,333,7419,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,136:4:0 0,12,138:4:0 +17 2172 . T 0 . DP=20;I16=11,9,0,0,732,27540,0,0,1200,72000,0,0,330,7346,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,149:4:0 0,12,147:4:0 +17 2173 . G 0 . DP=19;I16=10,9,0,0,704,26534,0,0,1140,68400,0,0,327,7243,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,142:4:0 0,12,133:4:0 +17 2174 . G 0 . DP=19;I16=10,9,0,0,674,24372,0,0,1140,68400,0,0,324,7158,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,126:4:0 0,12,129:4:0 +17 2175 . G 0 . DP=18;I16=9,9,0,0,639,23059,0,0,1080,64800,0,0,322,7090,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,123:4:0 0,12,126:4:0 +17 2176 . G 0 . DP=18;I16=9,9,0,0,621,21815,0,0,1080,64800,0,0,318,6940,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,12,121:4:0 0,12,123:4:0 +17 2177 . T 0 . DP=18;I16=9,9,0,0,547,18051,0,0,1080,64800,0,0,314,6810,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,239:10:0 0,12,83:4:0 0,12,108:4:0 +17 2178 . T 0 . DP=18;I16=9,9,0,0,579,19659,0,0,1080,64800,0,0,310,6700,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,234:10:0 0,12,110:4:0 0,12,118:4:0 +17 2179 . T 0 . DP=18;I16=9,9,0,0,591,20403,0,0,1080,64800,0,0,307,6609,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,239:10:0 0,12,97:4:0 0,12,135:4:0 +17 2180 . T 0 . DP=18;I16=9,9,0,0,616,21524,0,0,1080,64800,0,0,305,6537,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,236:10:0 0,12,122:4:0 0,12,133:4:0 +17 2181 . C 0 . DP=18;I16=9,8,0,0,611,22485,0,0,1020,61200,0,0,293,6385,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,224:9:0 0,12,129:4:0 0,12,150:4:0 +17 2182 . C 0 . DP=18;I16=9,9,0,0,665,24877,0,0,1080,64800,0,0,301,6453,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,125:4:0 0,12,145:4:0 +17 2183 . A 0 . DP=18;I16=9,9,0,0,646,23624,0,0,1080,64800,0,0,299,6441,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,12,123:4:0 0,12,144:4:0 +17 2184 . T 0 . DP=17;I16=8,9,0,0,610,22250,0,0,1020,61200,0,0,298,6448,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,224:9:0 0,12,134:4:0 0,12,136:4:0 +17 2185 . C 0 . DP=16;I16=8,8,0,0,569,20761,0,0,960,57600,0,0,297,6423,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,211:8:0 0,12,128:4:0 0,12,137:4:0 +17 2186 . A 0 . DP=16;I16=8,8,0,0,576,21314,0,0,960,57600,0,0,296,6416,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,204:8:0 0,12,134:4:0 0,12,145:4:0 +17 2187 . A 0 . DP=16;I16=8,8,0,0,562,20396,0,0,960,57600,0,0,295,6427,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,201:8:0 0,12,136:4:0 0,12,135:4:0 +17 2188 . A 0 . DP=17;I16=9,8,0,0,569,19925,0,0,1020,61200,0,0,293,6405,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,214:9:0 0,12,133:4:0 0,12,123:4:0 +17 2189 . C 0 . DP=19;I16=9,10,0,0,645,22647,0,0,1097,65089,0,0,292,6400,0,0;QS=3,0;MQSB=0.934728;MQ0F=0 PL:DP:DV 0,30,230:10:0 0,12,133:4:0 0,15,142:5:0 +17 2190 . C 0 . DP=19;I16=9,10,0,0,604,20072,0,0,1097,65089,0,0,294,6414,0,0;QS=3,0;MQSB=0.934728;MQ0F=0 PL:DP:DV 0,33,238:11:0 0,12,119:4:0 0,12,107:4:0 +17 2191 . C 0 . DP=19;I16=9,10,0,0,647,23007,0,0,1097,65089,0,0,297,6449,0,0;QS=3,0;MQSB=0.934728;MQ0F=0 PL:DP:DV 0,33,251:11:0 0,12,129:4:0 0,12,119:4:0 +17 2192 . T 0 . DP=19;I16=9,10,0,0,659,23723,0,0,1097,65089,0,0,300,6506,0,0;QS=3,0;MQSB=0.934728;MQ0F=0 PL:DP:DV 0,33,253:11:0 0,12,136:4:0 0,12,120:4:0 +17 2193 . C 0 . DP=18;I16=8,10,0,0,642,23934,0,0,1037,61489,0,0,303,6535,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,128:4:0 0,9,87:3:0 +17 2194 . A 0 . DP=18;I16=8,9,0,0,617,22683,0,0,1020,61200,0,0,301,6561,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,12,134:4:0 0,9,98:3:0 +17 2195 . A 0 . DP=18;I16=8,10,0,0,635,23271,0,0,1037,61489,0,0,309,6659,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,128:4:0 0,9,101:3:0 +17 2196 . G 0 . DP=19;I16=8,11,0,0,703,26383,0,0,1097,65089,0,0,312,6754,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,117:4:0 0,12,120:4:0 +17 2197 . A 0 . DP=19;I16=8,11,0,0,735,28599,0,0,1097,65089,0,0,314,6770,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,141:4:0 0,12,125:4:0 +17 2198 . G 0 . DP=19;I16=8,10,0,0,650,24206,0,0,1080,64800,0,0,307,6725,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,129:4:0 0,12,107:4:0 +17 2199 . C 0 . DP=19;I16=8,11,0,0,701,26735,0,0,1097,65089,0,0,318,6862,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,128:4:0 0,12,116:4:0 +17 2200 . T 0 . DP=19;I16=8,11,0,0,710,26768,0,0,1097,65089,0,0,320,6938,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,129:4:0 0,12,114:4:0 +17 2201 . G 0 . DP=17;I16=7,10,0,0,628,23764,0,0,977,57889,0,0,324,7032,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,66:2:0 0,12,119:4:0 +17 2202 . G 0 . DP=17;I16=7,10,0,0,557,19249,0,0,977,57889,0,0,327,7093,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,33,245:11:0 0,6,57:2:0 0,12,115:4:0 +17 2203 . G 0 . DP=17;I16=7,10,0,0,588,21184,0,0,977,57889,0,0,329,7123,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,47:2:0 0,12,116:4:0 +17 2204 . C 0 . DP=17;I16=7,10,0,0,538,18568,0,0,977,57889,0,0,331,7173,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,33,246:11:0 0,6,61:2:0 0,12,99:4:0 +17 2205 . C 0 . DP=18;I16=7,11,0,0,628,22918,0,0,1037,61489,0,0,332,7192,0,0;QS=3,0;MQSB=0.951002;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,68:2:0 0,12,109:4:0 +17 2206 . T 0 . DP=19;I16=7,12,0,0,677,25237,0,0,1097,65089,0,0,334,7230,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,77:2:0 0,12,115:4:0 +17 2207 . G 0 . DP=19;I16=7,11,0,0,663,24717,0,0,1080,64800,0,0,319,6965,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,67:2:0 0,12,110:4:0 +17 2208 . G 0 . DP=21;I16=7,14,0,0,726,26038,0,0,1217,72289,0,0,340,7370,0,0;QS=3,0;MQSB=0.966484;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,110:4:0 0,12,122:4:0 +17 2209 . G 0 . DP=22;I16=8,13,0,0,715,25133,0,0,1237,73369,0,0,325,7075,0,0;QS=3,0;MQSB=0.895122;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,128:5:0 0,12,117:4:0 +17 2210 . G C, 0 . DP=21;I16=7,13,0,1,648,22186,25,625,1177,69769,17,289,331,7165,21,441;QS=2.95442,0.0455764,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.975265;BQB=1;MQ0F=0 PL:DP:DV 0,19,234,33,237,241:12:1 0,15,127,15,127,127:5:0 0,12,113,12,113,113:4:0 +17 2211 . T 0 . DP=21;I16=7,13,0,0,724,27000,0,0,1177,69769,0,0,336,7230,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,141:5:0 0,12,124:4:0 +17 2212 . C 0 . DP=22;I16=8,14,0,0,791,29201,0,0,1254,73658,0,0,364,7850,0,0;QS=3,0;MQSB=0.985548;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,148:5:0 0,12,111:4:0 +17 2213 . A 0 . DP=22;I16=8,14,0,0,767,27327,0,0,1254,73658,0,0,371,8015,0,0;QS=3,0;MQSB=0.985548;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,153:5:0 0,12,112:4:0 +17 2214 . A 0 . DP=22;I16=8,14,0,0,756,26836,0,0,1254,73658,0,0,377,8159,0,0;QS=3,0;MQSB=0.985548;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,153:5:0 0,12,117:4:0 +17 2215 . C 0 . DP=22;I16=8,14,0,0,815,31121,0,0,1254,73658,0,0,381,8229,0,0;QS=3,0;MQSB=0.985548;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,162:5:0 0,12,124:4:0 +17 2216 . T 0 . DP=22;I16=8,14,0,0,815,31233,0,0,1254,73658,0,0,384,8272,0,0;QS=3,0;MQSB=0.985548;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,166:5:0 0,12,124:4:0 +17 2217 . T 0 . DP=22;I16=8,13,0,0,741,26855,0,0,1237,73369,0,0,362,7712,0,0;QS=3,0;MQSB=0.895122;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,155:5:0 0,12,118:4:0 +17 2218 . C 0 . DP=21;I16=7,14,0,0,753,27973,0,0,1194,70058,0,0,391,8423,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,138:4:0 0,12,119:4:0 +17 2219 . C 0 . DP=21;I16=7,13,0,0,757,29125,0,0,1177,69769,0,0,370,7904,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,141:4:0 0,12,122:4:0 +17 2220 . G A, 0 . DP=21;I16=6,2,1,11,256,8364,474,19128,457,26569,720,43200,141,2959,233,5071;QS=0.886504,2.1135,0;VDB=0.532753;SGB=-3.51597;RPB=0.964198;MQB=0.898397;MQSB=0.875769;BQB=0.0354359;MQ0F=0 PL:DP:DV 139,0,130,157,148,255:12:6 69,0,46,75,52,119:4:2 131,12,0,131,12,131:4:4 +17 2221 . G 0 . DP=21;I16=7,13,0,0,738,27922,0,0,1177,69769,0,0,376,8078,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,132:4:0 0,12,120:4:0 +17 2222 . C 0 . DP=21;I16=7,14,0,0,746,28098,0,0,1194,70058,0,0,401,8675,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,135:4:0 0,12,107:4:0 +17 2223 . C 0 . DP=21;I16=7,14,0,0,796,30632,0,0,1194,70058,0,0,401,8671,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,135:4:0 0,12,122:4:0 +17 2224 . T 0 . DP=21;I16=7,14,0,0,811,31599,0,0,1194,70058,0,0,401,8691,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,144:4:0 0,12,123:4:0 +17 2225 . G 0 . DP=21;I16=7,14,0,0,778,29396,0,0,1194,70058,0,0,401,8735,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,133:4:0 0,12,121:4:0 +17 2226 . G 0 . DP=21;I16=7,14,0,0,727,26485,0,0,1194,70058,0,0,401,8803,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,128:4:0 0,12,113:4:0 +17 2227 . G 0 . DP=20;I16=7,12,0,0,663,23985,0,0,1117,66169,0,0,377,8269,0,0;QS=3,0;MQSB=0.879351;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,123:4:0 0,12,114:4:0 +17 2228 . G C, 0 . DP=19;I16=5,12,0,1,643,24791,16,256,1020,61200,17,289,360,8020,25,625;QS=2.9603,0.0397022,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.970092;BQB=1;MQ0F=0 PL:DP:DV 0,17,255,30,255,255:11:1 0,9,95,9,95,95:3:0 0,12,121,12,121,121:4:0 +17 2229 . A 0 . DP=20;I16=6,14,0,0,757,28857,0,0,1134,66458,0,0,406,9138,0,0;QS=3,0;MQSB=0.959189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,138:4:0 0,12,122:4:0 +17 2230 . A 0 . DP=20;I16=6,14,0,0,729,26985,0,0,1134,66458,0,0,409,9291,0,0;QS=3,0;MQSB=0.959189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,141:4:0 0,12,119:4:0 +17 2231 . A 0 . DP=20;I16=6,13,0,0,712,26990,0,0,1117,66169,0,0,386,8790,0,0;QS=3,0;MQSB=0.850016;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,144:4:0 0,12,124:4:0 +17 2232 . C 0 . DP=20;I16=6,14,0,0,751,28657,0,0,1134,66458,0,0,412,9508,0,0;QS=3,0;MQSB=0.959189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,130:4:0 0,12,107:4:0 +17 2233 . T 0 . DP=20;I16=6,14,0,0,774,30432,0,0,1134,66458,0,0,413,9619,0,0;QS=3,0;MQSB=0.959189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,150:4:0 0,12,117:4:0 +17 2234 . G 0 . DP=20;I16=6,14,0,0,719,26621,0,0,1134,66458,0,0,412,9646,0,0;QS=3,0;MQSB=0.959189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,145:4:0 0,12,107:4:0 +17 2235 . G 0 . DP=20;I16=6,14,0,0,728,27036,0,0,1134,66458,0,0,410,9636,0,0;QS=3,0;MQSB=0.959189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,139:4:0 0,12,104:4:0 +17 2236 . G 0 . DP=19;I16=6,13,0,0,705,26985,0,0,1074,62858,0,0,409,9637,0,0;QS=3,0;MQSB=0.965977;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,142:4:0 0,9,84:3:0 +17 2237 . G 0 . DP=19;I16=6,12,0,0,684,26576,0,0,1057,62569,0,0,383,9023,0,0;QS=3,0;MQSB=0.85394;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,141:4:0 0,9,86:3:0 +17 2238 . C 0 . DP=19;I16=5,13,0,0,648,24496,0,0,1037,61489,0,0,381,8993,0,0;QS=3,0;MQSB=0.970092;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,108:3:0 0,9,78:3:0 +17 2239 . A 0 . DP=19;I16=6,11,0,0,634,24178,0,0,997,58969,0,0,373,8935,0,0;QS=3,0;MQSB=0.85832;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,133:4:0 0,6,77:2:0 +17 2240 . A 0 . DP=19;I16=6,13,0,0,731,28595,0,0,1074,62858,0,0,402,9582,0,0;QS=3,0;MQSB=0.965977;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,135:4:0 0,9,101:3:0 +17 2241 . G 0 . DP=19;I16=6,12,0,0,683,26433,0,0,1057,62569,0,0,375,8951,0,0;QS=3,0;MQSB=0.85394;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,126:4:0 0,9,88:3:0 +17 2242 . T 0 . DP=20;I16=5,13,0,0,635,22949,0,0,1057,62569,0,0,370,8944,0,0;QS=3,0;MQSB=0.814433;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,91:3:0 0,9,95:3:0 +17 2243 . A 0 . DP=19;I16=5,14,0,0,704,26274,0,0,1074,62858,0,0,395,9585,0,0;QS=3,0;MQSB=0.933727;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,107:3:0 0,9,99:3:0 +17 2244 . T 0 . DP=19;I16=5,14,0,0,681,25263,0,0,1074,62858,0,0,395,9609,0,0;QS=3,0;MQSB=0.933727;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,89:3:0 0,9,98:3:0 +17 2245 . C 0 . DP=19;I16=5,14,0,0,722,27846,0,0,1074,62858,0,0,394,9592,0,0;QS=3,0;MQSB=0.933727;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,98:3:0 0,9,88:3:0 +17 2246 . A 0 . DP=18;I16=5,12,0,0,597,21693,0,0,997,58969,0,0,367,8861,0,0;QS=3,0;MQSB=0.818731;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,95:3:0 0,6,72:2:0 +17 2247 . C 0 . DP=17;I16=4,13,0,0,639,24373,0,0,954,55658,0,0,391,9391,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,105:3:0 0,6,71:2:0 +17 2248 . C 0 . DP=17;I16=4,13,0,0,669,26863,0,0,954,55658,0,0,390,9306,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,90:3:0 0,6,75:2:0 +17 2249 . A 0 . DP=17;I16=4,13,0,0,677,27371,0,0,954,55658,0,0,389,9231,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,116:3:0 0,6,80:2:0 +17 2250 . G 0 . DP=17;I16=4,13,0,0,654,25800,0,0,954,55658,0,0,388,9166,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,100:3:0 0,6,78:2:0 +17 2251 . A 0 . DP=17;I16=4,13,0,0,673,27327,0,0,954,55658,0,0,387,9111,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,112:3:0 0,6,80:2:0 +17 2252 . G 0 . DP=17;I16=4,12,0,0,647,26249,0,0,937,55369,0,0,361,8441,0,0;QS=3,0;MQSB=0.767432;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,113:3:0 0,6,73:2:0 +17 2253 . A 0 . DP=17;I16=4,13,0,0,641,24643,0,0,954,55658,0,0,385,9031,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,111:3:0 0,6,73:2:0 +17 2254 . T 0 . DP=17;I16=4,12,0,0,615,23821,0,0,937,55369,0,0,358,8332,0,0;QS=3,0;MQSB=0.767432;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,112:3:0 0,6,73:2:0 +17 2255 . G 0 . DP=17;I16=4,13,0,0,677,27243,0,0,954,55658,0,0,380,8844,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,115:3:0 0,6,71:2:0 +17 2256 . A 0 . DP=17;I16=4,13,0,0,656,26088,0,0,954,55658,0,0,377,8741,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,110:3:0 0,6,78:2:0 +17 2257 . G 0 . DP=17;I16=4,12,0,0,627,24863,0,0,937,55369,0,0,349,8023,0,0;QS=3,0;MQSB=0.767432;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,115:3:0 0,6,74:2:0 +17 2258 . C 0 . DP=17;I16=4,13,0,0,667,26403,0,0,954,55658,0,0,371,8565,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,109:3:0 0,6,70:2:0 +17 2259 . T 0 . DP=17;I16=4,13,0,0,646,25334,0,0,954,55658,0,0,368,8492,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,116:3:0 0,6,79:2:0 +17 2260 . T 0 . DP=17;I16=4,13,0,0,638,24178,0,0,954,55658,0,0,365,8429,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,115:3:0 0,6,72:2:0 +17 2261 . T 0 . DP=17;I16=4,13,0,0,633,23799,0,0,954,55658,0,0,362,8376,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,105:3:0 0,6,73:2:0 +17 2262 . A 0 . DP=17;I16=4,13,0,0,628,23438,0,0,954,55658,0,0,359,8333,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,253:12:0 0,9,112:3:0 0,6,74:2:0 +17 2263 . T 0 . DP=17;I16=4,13,0,0,631,23673,0,0,954,55658,0,0,355,8251,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,112:3:0 0,6,74:2:0 +17 2264 . A 0 . DP=17;I16=4,12,0,0,623,24371,0,0,937,55369,0,0,326,7556,0,0;QS=3,0;MQSB=0.767432;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,114:3:0 0,6,75:2:0 +17 2265 . A 0 . DP=18;I16=4,13,0,0,642,24718,0,0,997,58969,0,0,320,7400,0,0;QS=3,0;MQSB=0.762744;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,113:3:0 0,6,75:2:0 +17 2266 . A 0 . DP=19;I16=5,14,0,0,656,23962,0,0,1074,62858,0,0,337,7745,0,0;QS=3,0;MQSB=0.933727;MQ0F=0 PL:DP:DV 0,39,252:13:0 0,12,128:4:0 0,6,75:2:0 +17 2267 . A 0 . DP=20;I16=6,14,0,0,712,26052,0,0,1134,66458,0,0,332,7582,0,0;QS=3,0;MQSB=0.959189;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,134:4:0 0,9,102:3:0 +17 2268 . A 0 . DP=20;I16=6,14,0,0,741,27841,0,0,1134,66458,0,0,327,7391,0,0;QS=3,0;MQSB=0.959189;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,135:4:0 0,9,100:3:0 +17 2269 . T 0 . DP=20;I16=6,13,0,0,681,24751,0,0,1074,62858,0,0,318,7206,0,0;QS=3,0;MQSB=0.965977;MQ0F=0 PL:DP:DV 0,36,246:12:0 0,12,137:4:0 0,9,111:3:0 +17 2270 . A 0 . DP=19;I16=6,12,0,0,652,24154,0,0,1057,62569,0,0,300,6750,0,0;QS=3,0;MQSB=0.85394;MQ0F=0 PL:DP:DV 0,33,244:11:0 0,12,134:4:0 0,9,112:3:0 +17 2271 . A 0 . DP=17;I16=6,11,0,0,654,25406,0,0,954,55658,0,0,316,6944,0,0;QS=3,0;MQSB=0.980001;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,12,142:4:0 0,9,111:3:0 +17 2272 . T 0 . DP=17;I16=6,10,0,0,604,22908,0,0,937,55369,0,0,297,6525,0,0;QS=3,0;MQSB=0.863243;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,12,137:4:0 0,9,111:3:0 +17 2273 . G 0 . DP=17;I16=6,10,0,0,581,22129,0,0,937,55369,0,0,295,6411,0,0;QS=3,0;MQSB=0.863243;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,12,123:4:0 0,9,115:3:0 +17 2274 . G 0 . DP=18;I16=6,11,0,0,621,23109,0,0,997,58969,0,0,293,6313,0,0;QS=3,0;MQSB=0.85832;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,12,132:4:0 0,9,110:3:0 +17 2275 . T 0 . DP=18;I16=6,11,0,0,624,23152,0,0,997,58969,0,0,292,6232,0,0;QS=3,0;MQSB=0.85832;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,12,126:4:0 0,9,113:3:0 +17 2276 . G 0 . DP=20;I16=7,12,0,0,710,26848,0,0,1074,62858,0,0,303,6313,0,0;QS=3,0;MQSB=0.985816;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,129:4:0 0,9,110:3:0 +17 2277 . C 0 . DP=21;I16=8,13,0,0,797,30699,0,0,1194,70058,0,0,303,6247,0,0;QS=3,0;MQSB=0.989565;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,151:5:0 0,12,143:4:0 +17 2278 . T 0 . DP=21;I16=7,13,0,0,736,27790,0,0,1157,68689,0,0,279,5581,0,0;QS=3,0;MQSB=0.962269;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,133:4:0 0,12,148:4:0 +17 2279 . A 0 . DP=20;I16=8,12,0,0,723,27047,0,0,1134,66458,0,0,306,6190,0,0;QS=3,0;MQSB=0.993326;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,155:5:0 0,12,144:4:0 +17 2280 . G 0 . DP=21;I16=8,12,0,0,766,29776,0,0,1177,69769,0,0,299,6085,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,166:5:0 0,12,144:4:0 +17 2281 . C 0 . DP=22;I16=8,13,0,0,784,29748,0,0,1237,73369,0,0,301,6037,0,0;QS=3,0;MQSB=0.895122;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,165:5:0 0,12,140:4:0 +17 2282 . T 0 . DP=22;I16=8,14,0,0,789,29699,0,0,1254,73658,0,0,310,6054,0,0;QS=3,0;MQSB=0.985548;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,162:5:0 0,12,150:4:0 +17 2283 . G 0 . DP=22;I16=8,14,0,0,798,29774,0,0,1254,73658,0,0,312,6054,0,0;QS=3,0;MQSB=0.985548;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,158:5:0 0,12,142:4:0 +17 2284 . G 0 . DP=22;I16=7,14,0,0,760,28408,0,0,1194,70058,0,0,294,5664,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,130:4:0 0,12,141:4:0 +17 2285 . G 0 . DP=23;I16=9,14,0,0,844,31592,0,0,1314,77258,0,0,311,5909,0,0;QS=3,0;MQSB=0.992095;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,152:5:0 0,12,144:4:0 +17 2286 . C 0 . DP=23;I16=9,14,0,0,854,32244,0,0,1314,77258,0,0,311,5869,0,0;QS=3,0;MQSB=0.992095;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,155:5:0 0,12,130:4:0 +17 2287 . A 0 . DP=23;I16=9,14,0,0,818,30288,0,0,1314,77258,0,0,311,5869,0,0;QS=3,0;MQSB=0.992095;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,166:5:0 0,12,143:4:0 +17 2288 . T 0 . DP=22;I16=8,14,0,0,794,29190,0,0,1254,73658,0,0,312,5908,0,0;QS=3,0;MQSB=0.985548;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,158:5:0 0,12,142:4:0 +17 2289 . G 0 . DP=21;I16=8,13,0,0,723,25835,0,0,1237,73369,0,0,314,5984,0,0;QS=3,0;MQSB=0.895122;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,154:5:0 0,12,126:4:0 +17 2290 . G 0 . DP=20;I16=7,13,0,0,748,28318,0,0,1177,69769,0,0,318,6094,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,149:5:0 0,9,114:3:0 +17 2291 . T 0 . DP=20;I16=7,13,0,0,731,27165,0,0,1177,69769,0,0,322,6186,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,151:5:0 0,9,112:3:0 +17 2292 . G 0 . DP=20;I16=7,13,0,0,749,28747,0,0,1177,69769,0,0,325,6259,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,156:5:0 0,9,109:3:0 +17 2293 . G 0 . DP=20;I16=7,13,0,0,739,27903,0,0,1177,69769,0,0,327,6311,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,156:5:0 0,9,112:3:0 +17 2294 . C 0 . DP=21;I16=7,14,0,0,775,29453,0,0,1237,73369,0,0,329,6391,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,169:5:0 0,9,114:3:0 +17 2295 . T 0 . DP=21;I16=7,14,0,0,773,29209,0,0,1237,73369,0,0,331,6451,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,164:5:0 0,9,115:3:0 +17 2296 . T 0 . DP=21;I16=7,14,0,0,756,27780,0,0,1237,73369,0,0,333,6543,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,160:5:0 0,9,106:3:0 +17 2297 . G 0 . DP=20;I16=7,13,0,0,736,27692,0,0,1177,69769,0,0,336,6666,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,165:5:0 0,6,74:2:0 +17 2298 . C 0 . DP=21;I16=7,14,0,0,778,29300,0,0,1237,73369,0,0,339,6819,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,139:5:0 0,9,106:3:0 +17 2299 . A 0 . DP=21;I16=7,14,0,0,714,25282,0,0,1237,73369,0,0,343,7003,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,128:5:0 0,9,110:3:0 +17 2300 . C 0 . DP=21;I16=7,13,0,0,687,24749,0,0,1177,69769,0,0,326,6768,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,148:5:0 0,9,109:3:0 +17 2301 . C 0 . DP=23;I16=7,15,0,0,802,30292,0,0,1266,74210,0,0,349,7363,0,0;QS=3,0;MQSB=0.970024;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,147:5:0 0,9,116:3:0 +17 2302 . T 0 . DP=23;I16=7,16,0,0,860,32956,0,0,1326,77810,0,0,354,7496,0,0;QS=3,0;MQSB=0.964916;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,166:5:0 0,12,150:4:0 +17 2303 . G 0 . DP=23;I16=7,16,0,0,817,29823,0,0,1326,77810,0,0,356,7604,0,0;QS=3,0;MQSB=0.964916;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,151:5:0 0,12,139:4:0 +17 2304 . T 0 . DP=23;I16=7,16,0,0,802,28628,0,0,1326,77810,0,0,357,7691,0,0;QS=3,0;MQSB=0.964916;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,148:5:0 0,12,140:4:0 +17 2305 . A 0 . DP=22;I16=7,14,0,0,725,25585,0,0,1237,73369,0,0,355,7791,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,36,248:12:0 0,15,155:5:0 0,12,129:4:0 +17 2306 . A 0 . DP=21;I16=7,14,0,0,727,26841,0,0,1206,70610,0,0,361,7899,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,36,246:12:0 0,15,168:5:0 0,12,130:4:0 +17 2307 . T 0 . DP=21;I16=7,14,0,0,751,27427,0,0,1206,70610,0,0,362,7964,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,36,251:12:0 0,15,165:5:0 0,12,141:4:0 +17 2308 . C 0 . DP=21;I16=7,14,0,0,735,26675,0,0,1206,70610,0,0,363,8051,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,144:5:0 0,12,146:4:0 +17 2309 . C A, 0 . DP=19;I16=7,11,0,1,604,21364,16,256,1057,62569,29,841,358,8094,8,64;QS=2.95676,0.0432432,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.985816;BQB=1;MQ0F=0 PL:DP:DV 0,20,224,33,227,230:12:1 0,9,94,9,94,94:3:0 0,12,138,12,138,138:4:0 +17 2310 . C 0 . DP=18;I16=6,12,0,0,668,25392,0,0,1049,62041,0,0,370,8282,0,0;QS=3,0;MQSB=0.961295;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,80:2:0 0,12,139:4:0 +17 2311 . A 0 . DP=19;I16=7,12,0,0,707,26855,0,0,1109,65641,0,0,373,8371,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,78:2:0 0,12,137:4:0 +17 2312 . G 0 . DP=20;I16=7,12,0,0,736,29118,0,0,1109,65641,0,0,364,8306,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,82:2:0 0,9,122:3:0 +17 2313 . C 0 . DP=20;I16=7,13,0,0,723,27231,0,0,1169,69241,0,0,382,8596,0,0;QS=3,0;MQSB=0.962269;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,76:2:0 0,12,130:4:0 +17 2314 . A 0 . DP=21;I16=7,12,0,0,630,22184,0,0,1109,65641,0,0,372,8510,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,78:2:0 0,9,115:3:0 +17 2315 . C 0 . DP=23;I16=7,14,0,0,739,26861,0,0,1229,72841,0,0,392,8892,0,0;QS=3,0;MQSB=0.966484;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,71:2:0 0,12,135:4:0 +17 2316 . T 0 . DP=23;I16=8,15,0,0,826,30690,0,0,1349,80041,0,0,408,9102,0,0;QS=3,0;MQSB=0.967216;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,105:3:0 0,15,170:5:0 +17 2317 . T 0 . DP=24;I16=7,16,0,0,766,27014,0,0,1349,80041,0,0,411,9211,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,78:2:0 0,15,170:5:0 +17 2318 . T 0 . DP=24;I16=8,14,0,0,757,27433,0,0,1320,79200,0,0,379,8449,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,91:3:0 0,15,165:5:0 +17 2319 . G 0 . DP=24;I16=6,16,0,0,827,31577,0,0,1289,76441,0,0,398,8882,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,43:1:0 0,15,167:5:0 +17 2320 . G 0 . DP=23;I16=7,16,0,0,803,29077,0,0,1349,80041,0,0,435,9675,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,87:3:0 0,15,157:5:0 +17 2321 . G 0 . DP=23;I16=7,16,0,0,804,29368,0,0,1349,80041,0,0,442,9840,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,79:3:0 0,15,169:5:0 +17 2322 . A 0 . DP=24;I16=7,17,0,0,860,32116,0,0,1409,83641,0,0,449,10027,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,95:3:0 0,15,178:5:0 +17 2323 . G 0 . DP=24;I16=7,17,0,0,863,31887,0,0,1409,83641,0,0,457,10237,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,88:3:0 0,15,153:5:0 +17 2324 . G 0 . DP=24;I16=7,16,0,0,786,27932,0,0,1349,80041,0,0,462,10416,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,88:3:0 0,15,161:5:0 +17 2325 . C 0 . DP=24;I16=7,15,0,0,730,25576,0,0,1289,76441,0,0,427,9625,0,0;QS=3,0;MQSB=0.970024;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,102:3:0 0,12,130:4:0 +17 2326 . C 0 . DP=24;I16=7,15,0,0,709,23523,0,0,1320,79200,0,0,426,9498,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,241:15:0 0,9,95:3:0 0,12,133:4:0 +17 2327 . G 0 . DP=24;I16=7,17,0,0,817,29275,0,0,1409,83641,0,0,481,10891,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,81:3:0 0,15,158:5:0 +17 2328 . A 0 . DP=24;I16=6,17,0,0,814,29804,0,0,1349,80041,0,0,461,10427,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,82:3:0 0,15,172:5:0 +17 2329 . G 0 . DP=23;I16=6,16,0,0,755,27641,0,0,1289,76441,0,0,477,11005,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,63:2:0 0,15,160:5:0 +17 2330 . C 0 . DP=24;I16=7,17,0,0,875,33131,0,0,1409,83641,0,0,498,11424,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,87:3:0 0,18,181:6:0 +17 2331 . T 0 . DP=24;I16=7,17,0,0,862,31882,0,0,1409,83641,0,0,505,11635,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,106:3:0 0,18,200:6:0 +17 2332 . A 0 . DP=25;I16=8,17,0,0,926,35412,0,0,1469,87241,0,0,512,11864,0,0;QS=3,0;MQSB=0.973216;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,97:3:0 0,18,204:6:0 +17 2333 . G 0 . DP=26;I16=8,17,0,0,923,35129,0,0,1469,87241,0,0,494,11436,0,0;QS=3,0;MQSB=0.973216;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,97:3:0 0,18,189:6:0 +17 2334 . G 0 . DP=26;I16=8,18,0,0,928,34574,0,0,1529,90841,0,0,527,12277,0,0;QS=3,0;MQSB=0.975611;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,93:3:0 0,21,202:7:0 +17 2335 . A 0 . DP=26;I16=8,18,0,0,967,36793,0,0,1529,90841,0,0,535,12513,0,0;QS=3,0;MQSB=0.975611;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,105:3:0 0,21,214:7:0 +17 2336 . G 0 . DP=26;I16=8,18,0,0,962,36346,0,0,1529,90841,0,0,543,12769,0,0;QS=3,0;MQSB=0.975611;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,92:3:0 0,21,204:7:0 +17 2337 . G 0 . DP=26;I16=7,18,0,0,895,32981,0,0,1469,87241,0,0,527,12465,0,0;QS=3,0;MQSB=0.977814;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,74:2:0 0,21,204:7:0 +17 2338 . A 0 . DP=26;I16=8,18,0,0,892,31758,0,0,1529,90841,0,0,556,13186,0,0;QS=3,0;MQSB=0.975611;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,87:3:0 0,21,194:7:0 +17 2339 . T 0 . DP=26;I16=7,18,0,0,827,28921,0,0,1469,87241,0,0,537,12769,0,0;QS=3,0;MQSB=0.977814;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,55:2:0 0,21,200:7:0 +17 2340 . C 0 . DP=25;I16=7,18,0,0,792,25816,0,0,1469,87241,0,0,541,12893,0,0;QS=3,0;MQSB=0.977814;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,57:2:0 0,21,173:7:0 +17 2341 . G 0 . DP=25;I16=6,17,0,0,771,26477,0,0,1349,80041,0,0,494,11732,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,3,41:1:0 0,21,186:7:0 +17 2342 . T 0 . DP=24;I16=6,17,0,0,863,32711,0,0,1349,80041,0,0,523,12459,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,3,43:1:0 0,21,214:7:0 +17 2343 . T 0 . DP=24;I16=6,16,0,0,770,28230,0,0,1289,76441,0,0,504,12032,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,44:1:0 0,21,213:7:0 +17 2344 . T 0 . DP=24;I16=7,17,0,0,843,30483,0,0,1409,83641,0,0,552,13124,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,56:2:0 0,21,202:7:0 +17 2345 . G 0 . DP=24;I16=7,17,0,0,897,34121,0,0,1409,83641,0,0,554,13162,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,77:2:0 0,21,206:7:0 +17 2346 . A 0 . DP=24;I16=7,17,0,0,908,34818,0,0,1409,83641,0,0,556,13212,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,68:2:0 0,21,220:7:0 +17 2347 . G 0 . DP=24;I16=6,17,0,0,824,30406,0,0,1349,80041,0,0,533,12649,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,3,39:1:0 0,21,190:7:0 +17 2348 . T 0 . DP=24;I16=7,16,0,0,745,25653,0,0,1349,80041,0,0,544,13072,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,64:2:0 0,18,183:6:0 +17 2349 . C 0 . DP=24;I16=6,17,0,0,804,29224,0,0,1349,80041,0,0,534,12656,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,3,36:1:0 0,21,200:7:0 +17 2350 . C 0 . DP=25;I16=7,17,0,0,869,31905,0,0,1409,83641,0,0,534,12652,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,63:2:0 0,21,198:7:0 +17 2351 . A 0 . DP=25;I16=8,17,0,0,945,36169,0,0,1469,87241,0,0,559,13237,0,0;QS=3,0;MQSB=0.973216;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,74:2:0 0,21,222:7:0 +17 2352 . G 0 . DP=25;I16=7,17,0,0,893,34005,0,0,1409,83641,0,0,533,12539,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,41:1:0 0,21,207:7:0 +17 2353 . C 0 . DP=24;I16=7,17,0,0,866,31864,0,0,1409,83641,0,0,531,12435,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,41:1:0 0,21,205:7:0 +17 2354 . A 0 . DP=24;I16=7,17,0,0,880,33206,0,0,1409,83641,0,0,529,12351,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,43:1:0 0,21,214:7:0 +17 2355 . G 0 . DP=24;I16=7,17,0,0,871,32261,0,0,1409,83641,0,0,526,12238,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,39:1:0 0,21,195:7:0 +17 2356 . T 0 . DP=24;I16=7,17,0,0,887,33305,0,0,1409,83641,0,0,521,12047,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,43:1:0 0,21,219:7:0 +17 2357 . T 0 . DP=24;I16=7,17,0,0,899,34225,0,0,1409,83641,0,0,516,11878,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,43:1:0 0,21,220:7:0 +17 2358 . T 0 . DP=24;I16=7,17,0,0,913,34891,0,0,1409,83641,0,0,510,11680,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,40:1:0 0,21,218:7:0 +17 2359 . G 0 . DP=25;I16=7,17,0,0,898,34048,0,0,1409,83641,0,0,503,11451,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,39:1:0 0,21,209:7:0 +17 2360 . A 0 . DP=25;I16=7,18,0,0,959,37113,0,0,1469,87241,0,0,514,11552,0,0;QS=3,0;MQSB=0.977814;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,72:2:0 0,21,222:7:0 +17 2361 . G 0 . DP=25;I16=7,17,0,0,850,30946,0,0,1409,83641,0,0,482,10726,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,67:2:0 0,18,168:6:0 +17 2362 . A 0 . DP=25;I16=7,17,0,0,762,25482,0,0,1409,83641,0,0,475,10547,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,51:2:0 0,18,159:6:0 +17 2363 . C 0 . DP=25;I16=7,18,0,0,875,31837,0,0,1469,87241,0,0,493,11015,0,0;QS=3,0;MQSB=0.977814;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,65:2:0 0,21,187:7:0 +17 2364 . C 0 . DP=25;I16=7,18,0,0,927,34965,0,0,1469,87241,0,0,486,10880,0,0;QS=3,0;MQSB=0.977814;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,64:2:0 0,21,201:7:0 +17 2365 . A 0 . DP=24;I16=7,17,0,0,908,34754,0,0,1409,83641,0,0,479,10717,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,65:2:0 0,21,221:7:0 +17 2366 . G 0 . DP=25;I16=7,17,0,0,912,35074,0,0,1440,86400,0,0,447,9951,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,58:2:0 0,21,206:7:0 +17 2367 . C 0 . DP=25;I16=7,17,0,0,872,32088,0,0,1409,83641,0,0,440,9782,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,36:1:0 0,21,197:7:0 +17 2368 . C 0 . DP=24;I16=6,17,0,0,871,33801,0,0,1349,80041,0,0,434,9634,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,39:1:0 0,18,180:6:0 +17 2369 . T 0 . DP=24;I16=6,18,0,0,877,33009,0,0,1409,83641,0,0,452,10082,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,49:2:0 0,18,179:6:0 +17 2370 . G 0 . DP=24;I16=6,18,0,0,899,34289,0,0,1409,83641,0,0,445,9927,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,56:2:0 0,18,179:6:0 +17 2371 . G 0 . DP=24;I16=6,18,0,0,880,33088,0,0,1409,83641,0,0,438,9794,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,51:2:0 0,18,177:6:0 +17 2372 . C 0 . DP=24;I16=6,18,0,0,827,29615,0,0,1409,83641,0,0,431,9683,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,47:2:0 0,18,163:6:0 +17 2373 . C 0 . DP=24;I16=6,18,0,0,886,33212,0,0,1409,83641,0,0,424,9594,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,58:2:0 0,18,166:6:0 +17 2374 . A 0 . DP=23;I16=6,17,0,0,844,31230,0,0,1349,80041,0,0,417,9477,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,66:2:0 0,18,177:6:0 +17 2375 . A 0 . DP=23;I16=5,17,0,0,788,28340,0,0,1289,76441,0,0,409,9333,0,0;QS=3,0;MQSB=0.981001;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,64:2:0 0,18,171:6:0 +17 2376 . T 0 . DP=22;I16=5,17,0,0,778,27804,0,0,1289,76441,0,0,401,9161,0,0;QS=3,0;MQSB=0.981001;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,62:2:0 0,18,162:6:0 +17 2377 . A 0 . DP=21;I16=4,17,0,0,704,24488,0,0,1229,72841,0,0,394,9008,0,0;QS=3,0;MQSB=0.984085;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,49:2:0 0,15,135:5:0 +17 2378 . C 0 . DP=20;I16=4,16,0,0,626,20138,0,0,1169,69241,0,0,388,8872,0,0;QS=3,0;MQSB=0.982301;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,15:1:0 0,15,108:5:0 +17 2379 . G 0 . DP=20;I16=4,16,0,0,714,25924,0,0,1169,69241,0,0,382,8752,0,0;QS=3,0;MQSB=0.982301;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,34:1:0 0,15,140:5:0 +17 2380 . G 0 . DP=19;I16=4,14,0,0,672,25672,0,0,1049,62041,0,0,352,8022,0,0;QS=3,0;MQSB=0.977696;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,18:1:0 0,15,134:5:0 +17 2381 . C 0 . DP=18;I16=4,14,0,0,676,25626,0,0,1049,62041,0,0,373,8555,0,0;QS=3,0;MQSB=0.977696;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,28:1:0 0,15,133:5:0 +17 2382 . A 0 . DP=19;I16=5,14,0,0,669,23995,0,0,1109,65641,0,0,369,8475,0,0;QS=3,0;MQSB=0.97357;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,28:1:0 0,15,131:5:0 +17 2383 . A 0 . DP=19;I16=5,14,0,0,686,25162,0,0,1109,65641,0,0,365,8359,0,0;QS=3,0;MQSB=0.97357;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,26:1:0 0,15,140:5:0 +17 2384 . A 0 . DP=19;I16=5,14,0,0,649,22943,0,0,1109,65641,0,0,360,8210,0,0;QS=3,0;MQSB=0.97357;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,13:1:0 0,15,132:5:0 +17 2385 . A 0 . DP=18;I16=4,14,0,0,643,23235,0,0,1049,62041,0,0,356,8078,0,0;QS=3,0;MQSB=0.977696;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,38:1:0 0,15,134:5:0 +17 2386 . C 0 . DP=18;I16=4,14,0,0,652,24008,0,0,1049,62041,0,0,351,7913,0,0;QS=3,0;MQSB=0.977696;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,25:1:0 0,15,130:5:0 +17 2387 . C 0 . DP=18;I16=4,14,0,0,667,25007,0,0,1049,62041,0,0,345,7717,0,0;QS=3,0;MQSB=0.977696;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,25:1:0 0,15,128:5:0 +17 2388 . C 0 . DP=18;I16=4,14,0,0,691,26659,0,0,1049,62041,0,0,339,7541,0,0;QS=3,0;MQSB=0.977696;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,39:1:0 0,15,134:5:0 +17 2389 . A 0 . DP=19;I16=5,14,0,0,682,24912,0,0,1109,65641,0,0,333,7385,0,0;QS=3,0;MQSB=0.97357;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,35:1:0 0,15,140:5:0 +17 2390 . G 0 . DP=18;I16=5,13,0,0,642,23418,0,0,1049,62041,0,0,328,7200,0,0;QS=3,0;MQSB=0.970092;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,27:1:0 0,15,126:5:0 +17 2391 . T 0 . DP=18;I16=5,12,0,0,624,23122,0,0,989,58441,0,0,298,6412,0,0;QS=2,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,0,0:0:0 0,15,140:5:0 +17 2392 . C 0 . DP=18;I16=5,12,0,0,660,25910,0,0,989,58441,0,0,291,6171,0,0;QS=2,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,0,0:0:0 0,15,131:5:0 +17 2393 . T 0 . DP=18;I16=5,13,0,0,669,25099,0,0,1049,62041,0,0,309,6577,0,0;QS=3,0;MQSB=0.970092;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,38:1:0 0,15,134:5:0 +17 2394 . C 0 . DP=17;I16=5,12,0,0,653,25323,0,0,989,58441,0,0,303,6379,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,29:1:0 0,15,133:5:0 +17 2395 . T 0 . DP=17;I16=5,12,0,0,613,22621,0,0,989,58441,0,0,297,6201,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,19:1:0 0,15,128:5:0 +17 2396 . A 0 . DP=17;I16=5,11,0,0,584,21426,0,0,929,54841,0,0,266,5418,0,0;QS=2,0;MQSB=0.960687;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,0,0:0:0 0,15,130:5:0 +17 2397 . C 0 . DP=18;I16=5,13,0,0,650,24046,0,0,1049,62041,0,0,284,5856,0,0;QS=3,0;MQSB=0.970092;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,18:1:0 0,15,129:5:0 +17 2398 . A 0 . DP=18;I16=5,13,0,0,617,21907,0,0,1049,62041,0,0,278,5692,0,0;QS=3,0;MQSB=0.970092;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,19:1:0 0,15,128:5:0 +17 2399 . A 0 . DP=17;I16=5,11,0,0,592,22176,0,0,929,54841,0,0,248,4926,0,0;QS=2,0;MQSB=0.960687;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,0,0:0:0 0,12,115:4:0 +17 2400 . A 0 . DP=16;I16=5,11,0,0,576,21010,0,0,929,54841,0,0,269,5431,0,0;QS=3,0;MQSB=0.960687;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,26:1:0 0,9,99:3:0 +17 2401 . A 0 . DP=17;I16=6,11,0,0,594,21126,0,0,989,58441,0,0,265,5331,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,23:1:0 0,9,98:3:0 +17 2402 . A 0 . DP=17;I16=6,11,0,0,606,21986,0,0,989,58441,0,0,262,5252,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,27:1:0 0,9,99:3:0 +17 2403 . A 0 . DP=17;I16=6,11,0,0,608,22130,0,0,989,58441,0,0,259,5195,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,21:1:0 0,9,97:3:0 +17 2404 . T 0 . DP=17;I16=6,11,0,0,567,19449,0,0,989,58441,0,0,256,5160,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,14:1:0 0,9,87:3:0 +17 2405 . A 0 . DP=18;I16=7,11,0,0,618,21666,0,0,1049,62041,0,0,253,5147,0,0;QS=3,0;MQSB=0.951002;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,17:1:0 0,9,88:3:0 +17 2406 . C 0 . DP=18;I16=7,11,0,0,676,25664,0,0,1049,62041,0,0,250,5108,0,0;QS=3,0;MQSB=0.951002;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,27:1:0 0,9,90:3:0 +17 2407 . A 0 . DP=19;I16=8,11,0,0,673,24197,0,0,1109,65641,0,0,246,5046,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,3,34:1:0 0,9,89:3:0 +17 2408 . A 0 . DP=18;I16=8,10,0,0,619,21951,0,0,1049,62041,0,0,243,4961,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,3,22:1:0 0,6,73:2:0 +17 2409 . A 0 . DP=17;I16=8,9,0,0,615,22687,0,0,1020,61200,0,0,240,4852,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,39:1:0 0,6,74:2:0 +17 2410 . A 0 . DP=17;I16=8,9,0,0,604,21938,0,0,1020,61200,0,0,237,4769,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,39:1:0 0,6,73:2:0 +17 2411 . A 0 . DP=16;I16=7,9,0,0,567,20551,0,0,960,57600,0,0,235,4711,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,25:1:0 0,6,70:2:0 +17 2412 . A 0 . DP=15;I16=7,8,0,0,527,18903,0,0,900,54000,0,0,234,4676,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,21:1:0 0,6,70:2:0 +17 2413 . C 0 . DP=15;I16=7,8,0,0,559,21161,0,0,900,54000,0,0,233,4663,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,22:1:0 0,6,72:2:0 +17 2414 . A 0 . DP=16;I16=8,8,0,0,570,20822,0,0,929,54841,0,0,232,4672,0,0;QS=3,0;MQSB=0.915545;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,25:1:0 0,6,73:2:0 +17 2415 . A 0 . DP=16;I16=9,7,0,0,574,20768,0,0,929,54841,0,0,232,4652,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,30:1:0 0,6,64:2:0 +17 2416 . C 0 . DP=17;I16=8,8,0,0,576,21424,0,0,960,57600,0,0,231,4649,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,42:2:0 0,6,68:2:0 +17 2417 . T 0 . DP=17;I16=10,7,0,0,612,22740,0,0,958,55682,0,0,235,4627,0,0;QS=3,0;MQSB=0.79189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,57:2:0 0,9,92:3:0 +17 2418 . A 0 . DP=17;I16=10,7,0,0,624,23210,0,0,958,55682,0,0,238,4626,0,0;QS=3,0;MQSB=0.79189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,62:2:0 0,9,105:3:0 +17 2419 . G 0 . DP=19;I16=11,7,0,0,651,24113,0,0,1018,59282,0,0,241,4651,0,0;QS=3,0;MQSB=0.817948;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,51:2:0 0,12,126:4:0 +17 2420 . C 0 . DP=19;I16=11,8,0,0,663,23999,0,0,1078,62882,0,0,246,4704,0,0;QS=3,0;MQSB=0.803979;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,44:2:0 0,12,127:4:0 +17 2421 . C 0 . DP=19;I16=10,8,0,0,657,24779,0,0,1049,62041,0,0,244,4738,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,45:2:0 0,12,126:4:0 +17 2422 . A 0 . DP=18;I16=11,6,0,0,647,24747,0,0,958,55682,0,0,238,4538,0,0;QS=3,0;MQSB=0.833753;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,33:1:0 0,12,137:4:0 +17 2423 . G 0 . DP=18;I16=11,6,0,0,634,24250,0,0,958,55682,0,0,258,4972,0,0;QS=3,0;MQSB=0.833753;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,54:2:0 0,12,126:4:0 +17 2424 . G 0 . DP=18;I16=10,6,0,0,595,22361,0,0,929,54841,0,0,240,4714,0,0;QS=3,0;MQSB=0.948436;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,36:1:0 0,12,126:4:0 +17 2425 . C 0 . DP=18;I16=10,7,0,0,596,21716,0,0,989,58441,0,0,260,5074,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,45:2:0 0,12,114:4:0 +17 2426 . G 0 . DP=18;I16=10,7,0,0,550,18088,0,0,989,58441,0,0,263,5171,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,33,232:11:0 0,6,59:2:0 0,12,113:4:0 +17 2427 . T 0 . DP=18;I16=11,6,0,0,618,22654,0,0,958,55682,0,0,275,5403,0,0;QS=3,0;MQSB=0.833753;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,62:2:0 0,9,99:3:0 +17 2428 . G 0 . DP=18;I16=11,7,0,0,649,24633,0,0,1018,59282,0,0,281,5535,0,0;QS=3,0;MQSB=0.817948;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,48:2:0 0,12,128:4:0 +17 2429 . G 0 . DP=18;I16=10,7,0,0,553,19057,0,0,989,58441,0,0,269,5459,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,33,241:11:0 0,6,55:2:0 0,12,117:4:0 +17 2430 . T A, 0 . DP=18;I16=10,7,1,0,552,18556,21,441,989,58441,29,841,271,5603,16,256;QS=2.94278,0.0572207,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.817948;BQB=1;MQ0F=0 PL:DP:DV 0,15,212,33,215,222:12:1 0,6,60,6,60,60:2:0 0,12,125,12,125,125:4:0 +17 2431 . G 0 . DP=18;I16=11,5,0,0,580,21766,0,0,898,52082,0,0,268,5764,0,0;QS=3,0;MQSB=0.851779;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,37:1:0 0,9,98:3:0 +17 2432 . G 0 . DP=17;I16=10,7,0,0,593,21479,0,0,958,55682,0,0,295,6179,0,0;QS=3,0;MQSB=0.79189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,53:2:0 0,9,97:3:0 +17 2433 . T 0 . DP=17;I16=10,7,0,0,577,20425,0,0,958,55682,0,0,299,6321,0,0;QS=3,0;MQSB=0.79189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,57:2:0 0,9,94:3:0 +17 2434 . G 0 . DP=17;I16=10,6,0,0,546,19340,0,0,929,54841,0,0,284,6082,0,0;QS=3,0;MQSB=0.948436;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,46:2:0 0,6,62:2:0 +17 2435 . C 0 . DP=18;I16=12,5,0,0,597,21843,0,0,958,55682,0,0,304,6626,0,0;QS=3,0;MQSB=0.870325;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,58:2:0 0,6,60:2:0 +17 2436 . A 0 . DP=18;I16=11,6,0,0,545,18599,0,0,989,58441,0,0,295,6379,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,64:3:0 0,6,61:2:0 +17 2437 . C 0 . DP=18;I16=11,5,0,0,573,21195,0,0,929,54841,0,0,297,6541,0,0;QS=3,0;MQSB=0.960687;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,63:2:0 0,6,63:2:0 +17 2438 . A 0 . DP=19;I16=12,6,0,0,583,20111,0,0,1018,59282,0,0,328,7322,0,0;QS=3,0;MQSB=0.85394;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,65:2:0 0,6,65:2:0 +17 2439 . C 0 . DP=19;I16=11,7,0,0,635,22997,0,0,1049,62041,0,0,314,6974,0,0;QS=3,0;MQSB=0.951002;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,91:3:0 0,6,57:2:0 +17 2440 . C 0 . DP=21;I16=13,7,0,0,701,26195,0,0,1138,66482,0,0,346,7840,0,0;QS=3,0;MQSB=0.857404;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,114:4:0 0,6,66:2:0 +17 2441 . T 0 . DP=21;I16=13,8,0,0,788,29910,0,0,1198,70082,0,0,360,8068,0,0;QS=3,0;MQSB=0.845496;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,164:5:0 0,6,67:2:0 +17 2442 . G 0 . DP=20;I16=12,7,0,0,695,25957,0,0,1109,65641,0,0,342,7596,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,128:4:0 0,6,66:2:0 +17 2443 . T 0 . DP=20;I16=13,7,0,0,697,24685,0,0,1138,66482,0,0,373,8345,0,0;QS=3,0;MQSB=0.857404;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,130:4:0 0,6,64:2:0 +17 2444 . A 0 . DP=21;I16=13,8,0,0,755,27981,0,0,1198,70082,0,0,379,8489,0,0;QS=3,0;MQSB=0.845496;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,140:4:0 0,6,64:2:0 +17 2445 . G 0 . DP=21;I16=12,8,0,0,731,27427,0,0,1169,69241,0,0,359,7927,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,130:4:0 0,6,65:2:0 +17 2446 . T 0 . DP=21;I16=13,8,0,0,723,25707,0,0,1198,70082,0,0,389,8633,0,0;QS=3,0;MQSB=0.845496;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,128:4:0 0,6,65:2:0 +17 2447 . C 0 . DP=22;I16=14,8,0,0,770,27950,0,0,1258,73682,0,0,394,8732,0,0;QS=3,0;MQSB=0.86151;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,127:4:0 0,6,64:2:0 +17 2448 . C 0 . DP=23;I16=14,7,0,0,727,26165,0,0,1167,67323,0,0,388,8674,0,0;QS=3,0;MQSB=0.735784;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,129:5:0 0,6,66:2:0 +17 2449 . C 0 . DP=23;I16=13,8,0,0,727,26415,0,0,1198,70082,0,0,363,7787,0,0;QS=3,0;MQSB=0.845496;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,128:5:0 0,6,62:2:0 +17 2450 . A 0 . DP=22;I16=12,8,0,0,673,24267,0,0,1138,66482,0,0,371,7959,0,0;QS=3,0;MQSB=0.826565;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,143:5:0 0,6,65:2:0 +17 2451 . G 0 . DP=22;I16=14,8,0,0,821,31595,0,0,1227,70923,0,0,429,9401,0,0;QS=3,0;MQSB=0.715049;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,151:5:0 0,6,67:2:0 +17 2452 . C 0 . DP=22;I16=14,8,0,0,743,26557,0,0,1227,70923,0,0,437,9613,0,0;QS=3,0;MQSB=0.715049;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,137:5:0 0,6,66:2:0 +17 2453 . T 0 . DP=22;I16=14,8,0,0,775,28215,0,0,1227,70923,0,0,445,9845,0,0;QS=3,0;MQSB=0.715049;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,143:5:0 0,6,68:2:0 +17 2454 . A 0 . DP=22;I16=14,8,0,0,721,24545,0,0,1227,70923,0,0,453,10097,0,0;QS=3,0;MQSB=0.715049;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,145:5:0 0,6,64:2:0 +17 2455 . C 0 . DP=22;I16=14,8,0,0,776,28212,0,0,1227,70923,0,0,461,10369,0,0;QS=3,0;MQSB=0.715049;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,138:5:0 0,6,65:2:0 +17 2456 . T 0 . DP=24;I16=14,9,0,0,834,30902,0,0,1318,77282,0,0,444,10036,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,168:6:0 0,6,60:2:0 +17 2457 . C 0 . DP=24;I16=15,9,0,0,816,29244,0,0,1347,78123,0,0,478,10924,0,0;QS=3,0;MQSB=0.72325;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,159:6:0 0,6,65:2:0 +17 2458 . A 0 . DP=24;I16=15,9,0,0,869,32555,0,0,1347,78123,0,0,487,11209,0,0;QS=3,0;MQSB=0.72325;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,166:6:0 0,6,65:2:0 +17 2459 . G T, 0 . DP=24;I16=13,9,1,0,822,31186,13,169,1289,76441,29,841,453,10551,17,289;QS=2.92973,0.0702703,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.851535;BQB=1;MQ0F=0 PL:DP:DV 0,45,255,45,255,255:15:0 0,5,138,15,141,144:6:1 0,6,64,6,64,64:2:0 +17 2460 . G 0 . DP=24;I16=14,9,0,0,834,31432,0,0,1318,77282,0,0,477,11065,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,160:6:0 0,6,65:2:0 +17 2461 . A G, 0 . DP=24;I16=14,9,1,0,839,31487,13,169,1318,77282,29,841,489,11521,19,361;QS=2.93401,0.0659898,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.72325;BQB=1;MQ0F=0 PL:DP:DV 0,48,255,48,255,255:16:0 0,5,148,15,151,154:6:1 0,6,67,6,67,67:2:0 +17 2462 . G 0 . DP=25;I16=15,10,0,0,893,33155,0,0,1407,81723,0,0,514,12090,0,0;QS=3,0;MQSB=0.707404;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,165:6:0 0,6,66:2:0 +17 2463 . G T, 0 . DP=25;I16=12,10,1,0,777,28525,14,196,1289,76441,29,841,452,10720,25,625;QS=2.975,0.025,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.825053;BQB=1;MQ0F=0 PL:DP:DV 0,36,255,48,255,255:17:1 0,12,133,12,133,133:4:0 0,6,68,6,68,68:2:0 +17 2464 . C 0 . DP=25;I16=15,10,0,0,904,34194,0,0,1407,81723,0,0,526,12458,0,0;QS=3,0;MQSB=0.707404;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,149:6:0 0,6,67:2:0 +17 2465 . T 0 . DP=25;I16=14,10,0,0,857,32235,0,0,1347,78123,0,0,506,11994,0,0;QS=3,0;MQSB=0.679965;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,163:6:0 0,6,69:2:0 +17 2466 . G 0 . DP=24;I16=14,9,0,0,852,32336,0,0,1318,77282,0,0,509,12025,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,157:6:0 0,6,63:2:0 +17 2467 . A 0 . DP=24;I16=14,9,0,0,829,30725,0,0,1318,77282,0,0,513,12121,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,168:6:0 0,6,67:2:0 +17 2468 . G 0 . DP=24;I16=15,9,0,0,890,34034,0,0,1347,78123,0,0,541,12807,0,0;QS=3,0;MQSB=0.72325;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,169:6:0 0,6,64:2:0 +17 2469 . G 0 . DP=24;I16=15,9,0,0,865,32303,0,0,1347,78123,0,0,544,12882,0,0;QS=3,0;MQSB=0.72325;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,174:6:0 0,6,58:2:0 +17 2470 . G 0 . DP=24;I16=14,9,0,0,829,30785,0,0,1318,77282,0,0,521,12295,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,178:6:0 0,6,58:2:0 +17 2471 . G 0 . DP=24;I16=14,9,0,0,833,31429,0,0,1318,77282,0,0,523,12345,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,170:5:0 0,6,64:2:0 +17 2472 . G 0 . DP=24;I16=13,9,0,0,774,28428,0,0,1289,76441,0,0,499,11733,0,0;QS=3,0;MQSB=0.955854;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,154:5:0 0,6,56:2:0 +17 2473 . A 0 . DP=24;I16=13,9,0,0,775,28137,0,0,1258,73682,0,0,508,12078,0,0;QS=3,0;MQSB=0.834768;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,160:5:0 0,6,63:2:0 +17 2474 . A 0 . DP=25;I16=15,9,0,0,851,31665,0,0,1378,80882,0,0,524,12322,0,0;QS=3,0;MQSB=0.865888;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,160:5:0 0,9,80:3:0 +17 2475 . G 0 . DP=25;I16=15,9,0,0,913,35239,0,0,1378,80882,0,0,525,12323,0,0;QS=3,0;MQSB=0.865888;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,167:5:0 0,9,84:3:0 +17 2476 . G 0 . DP=25;I16=13,9,0,0,776,28584,0,0,1289,76441,0,0,488,11544,0,0;QS=3,0;MQSB=0.955854;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,138:5:0 0,9,82:3:0 +17 2477 . A 0 . DP=25;I16=14,9,0,0,867,34329,0,0,1318,77282,0,0,515,12223,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,178:5:0 0,9,91:3:0 +17 2478 . C 0 . DP=25;I16=14,9,0,0,897,36911,0,0,1318,77282,0,0,517,12289,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,175:5:0 0,9,87:3:0 +17 2479 . T 0 . DP=25;I16=15,9,0,0,921,37957,0,0,1378,80882,0,0,529,12467,0,0;QS=3,0;MQSB=0.865888;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,176:5:0 0,9,97:3:0 +17 2480 . G 0 . DP=25;I16=14,9,0,0,877,35485,0,0,1349,80041,0,0,504,11864,0,0;QS=3,0;MQSB=0.960618;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,176:5:0 0,9,88:3:0 +17 2481 . C 0 . DP=25;I16=13,9,0,0,848,34542,0,0,1289,76441,0,0,496,11838,0,0;QS=3,0;MQSB=0.955854;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,183:5:0 0,9,88:3:0 +17 2482 . T 0 . DP=25;I16=15,9,0,0,905,37331,0,0,1378,80882,0,0,526,12430,0,0;QS=3,0;MQSB=0.865888;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,178:5:0 0,9,96:3:0 +17 2483 . T 0 . DP=25;I16=14,9,0,0,879,36187,0,0,1318,77282,0,0,517,12311,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,180:5:0 0,9,89:3:0 +17 2484 . G 0 . DP=25;I16=14,9,0,0,884,35142,0,0,1349,80041,0,0,494,11604,0,0;QS=3,0;MQSB=0.960618;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,174:5:0 0,9,84:3:0 +17 2485 . A T, 0 . DP=25;I16=14,9,1,0,891,36757,17,289,1349,80041,29,841,490,11502,25,625;QS=2.96926,0.0307414,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.865888;BQB=1;MQ0F=0 PL:DP:DV 0,31,255,45,255,255:16:1 0,15,193,15,193,193:5:0 0,9,93,9,93,93:3:0 +17 2486 . G 0 . DP=25;I16=15,9,0,0,898,36230,0,0,1378,80882,0,0,511,12041,0,0;QS=3,0;MQSB=0.865888;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,153:5:0 0,9,90:3:0 +17 2487 . C 0 . DP=25;I16=14,9,0,0,793,30695,0,0,1349,80041,0,0,482,11346,0,0;QS=3,0;MQSB=0.960618;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,175:5:0 0,9,91:3:0 +17 2488 . C 0 . DP=25;I16=13,9,0,0,841,34597,0,0,1289,76441,0,0,457,10841,0,0;QS=3,0;MQSB=0.955854;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,174:5:0 0,9,93:3:0 +17 2489 . C 0 . DP=23;I16=11,9,0,0,801,34227,0,0,1169,69241,0,0,454,10788,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,187:5:0 0,9,93:3:0 +17 2490 . A 0 . DP=23;I16=11,10,0,0,818,34642,0,0,1229,72841,0,0,451,10695,0,0;QS=3,0;MQSB=0.939898;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,175:5:0 0,12,128:4:0 +17 2491 . G 0 . DP=23;I16=12,10,0,0,845,35143,0,0,1258,73682,0,0,471,11097,0,0;QS=3,0;MQSB=0.804615;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,178:5:0 0,12,121:4:0 +17 2492 . G A, 0 . DP=23;I16=11,10,1,0,845,36207,16,256,1229,72841,29,841,446,10494,21,441;QS=2.96708,0.0329218,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.804615;BQB=1;MQ0F=0 PL:DP:DV 0,22,255,36,255,255:13:1 0,15,187,15,187,187:5:0 0,12,124,12,124,124:4:0 +17 2493 . A G, 0 . DP=23;I16=11,10,1,0,855,37007,13,169,1229,72841,29,841,442,10340,20,400;QS=2.97269,0.0273109,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.804615;BQB=1;MQ0F=0 PL:DP:DV 0,25,255,36,255,255:13:1 0,15,191,15,191,191:5:0 0,12,127,12,127,127:4:0 +17 2494 . G 0 . DP=23;I16=11,10,0,0,802,32720,0,0,1229,72841,0,0,437,10153,0,0;QS=3,0;MQSB=0.939898;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,179:5:0 0,12,118:4:0 +17 2495 . T 0 . DP=23;I16=10,10,0,0,737,29861,0,0,1138,66482,0,0,413,9513,0,0;QS=3,0;MQSB=0.751477;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,172:5:0 0,12,113:4:0 +17 2496 . T 0 . DP=23;I16=12,10,0,0,815,32793,0,0,1258,73682,0,0,442,10026,0,0;QS=3,0;MQSB=0.804615;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,183:5:0 0,12,123:4:0 +17 2497 . T 0 . DP=22;I16=12,9,0,0,807,33723,0,0,1198,70082,0,0,436,9814,0,0;QS=3,0;MQSB=0.815018;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,177:5:0 0,12,131:4:0 +17 2498 . G 0 . DP=22;I16=12,9,0,0,808,33264,0,0,1198,70082,0,0,430,9622,0,0;QS=3,0;MQSB=0.815018;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,173:5:0 0,12,127:4:0 +17 2499 . A 0 . DP=22;I16=12,9,0,0,847,36803,0,0,1198,70082,0,0,424,9450,0,0;QS=3,0;MQSB=0.815018;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,185:5:0 0,12,133:4:0 +17 2500 . G 0 . DP=22;I16=11,9,0,0,772,32546,0,0,1169,69241,0,0,404,9078,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,168:5:0 0,12,129:4:0 +17 2501 . G 0 . DP=22;I16=11,8,0,0,768,33120,0,0,1109,65641,0,0,373,8293,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,146:4:0 0,12,118:4:0 +17 2502 . C 0 . DP=22;I16=12,8,0,0,798,33902,0,0,1138,66482,0,0,378,8270,0,0;QS=3,0;MQSB=0.826565;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,155:4:0 0,12,125:4:0 +17 2503 . T 0 . DP=22;I16=12,9,0,0,851,36841,0,0,1198,70082,0,0,396,8746,0,0;QS=3,0;MQSB=0.815018;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,180:5:0 0,12,139:4:0 +17 2504 . G 0 . DP=22;I16=12,9,0,0,787,31955,0,0,1198,70082,0,0,389,8615,0,0;QS=3,0;MQSB=0.815018;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,171:5:0 0,12,129:4:0 +17 2505 . C 0 . DP=21;I16=11,9,0,0,792,33440,0,0,1138,66482,0,0,383,8501,0,0;QS=3,0;MQSB=0.791547;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,169:5:0 0,12,132:4:0 +17 2506 . T 0 . DP=22;I16=11,10,0,0,798,32868,0,0,1198,70082,0,0,376,8354,0,0;QS=3,0;MQSB=0.780412;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,175:5:0 0,15,169:5:0 +17 2507 . G 0 . DP=21;I16=9,10,0,0,716,30074,0,0,1109,65641,0,0,365,8189,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,15,163:5:0 0,15,153:5:0 +17 2508 . T 0 . DP=21;I16=9,10,0,0,724,30396,0,0,1109,65641,0,0,361,8089,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,15,158:5:0 0,15,162:5:0 +17 2509 . G T, 0 . DP=21;I16=8,10,1,0,710,30408,35,1225,1049,62041,60,3600,330,7282,25,625;QS=2.80663,0.19337,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.920044;BQB=1;MQ0F=0 PL:DP:DV 0,27,253,27,253,253:9:0 20,0,122,32,125,150:5:1 0,15,163,15,163,163:5:0 +17 2510 . A 0 . DP=21;I16=10,10,0,0,778,33128,0,0,1138,66482,0,0,352,7754,0,0;QS=3,0;MQSB=0.751477;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,174:5:0 0,15,161:5:0 +17 2511 . G 0 . DP=21;I16=10,10,0,0,771,32165,0,0,1138,66482,0,0,344,7558,0,0;QS=3,0;MQSB=0.751477;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,161:5:0 0,15,159:5:0 +17 2512 . C 0 . DP=21;I16=10,10,0,0,790,33406,0,0,1138,66482,0,0,336,7386,0,0;QS=3,0;MQSB=0.751477;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,175:5:0 0,15,160:5:0 +17 2513 . T 0 . DP=21;I16=10,10,0,0,755,31503,0,0,1138,66482,0,0,327,7189,0,0;QS=3,0;MQSB=0.751477;MQ0F=0 PL:DP:DV 0,30,246:10:0 0,15,180:5:0 0,15,156:5:0 +17 2514 . G 0 . DP=20;I16=9,10,0,0,702,28002,0,0,1109,65641,0,0,319,7017,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,15,171:5:0 0,15,155:5:0 +17 2515 . T 0 . DP=19;I16=8,10,0,0,642,25888,0,0,1049,62041,0,0,312,6868,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,24,182:8:0 0,15,172:5:0 0,15,141:5:0 +17 2516 . G 0 . DP=19;I16=8,10,0,0,685,28155,0,0,1049,62041,0,0,303,6641,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,24,211:8:0 0,15,175:5:0 0,15,147:5:0 +17 2517 . A 0 . DP=18;I16=8,9,0,0,660,27600,0,0,989,58441,0,0,295,6435,0,0;QS=3,0;MQSB=0.91051;MQ0F=0 PL:DP:DV 0,24,215:8:0 0,12,139:4:0 0,15,161:5:0 +17 2518 . T 0 . DP=17;I16=6,9,0,0,611,26911,0,0,900,54000,0,0,273,6023,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,188:7:0 0,12,144:4:0 0,12,146:4:0 +17 2519 . C 0 . DP=16;I16=7,8,0,0,531,20111,0,0,900,54000,0,0,282,6078,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,175:7:0 0,12,141:4:0 0,12,125:4:0 +17 2520 . G 0 . DP=15;I16=6,8,0,0,501,19731,0,0,840,50400,0,0,277,5923,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,187:7:0 0,12,129:4:0 0,9,101:3:0 +17 2521 . C 0 . DP=15;I16=6,8,0,0,583,25777,0,0,840,50400,0,0,272,5782,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,214:7:0 0,12,149:4:0 0,9,111:3:0 +17 2522 . A 0 . DP=16;I16=6,8,0,0,516,20930,0,0,840,50400,0,0,266,5606,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,173:7:0 0,12,139:4:0 0,9,114:3:0 +17 2523 . T 0 . DP=16;I16=6,9,0,0,588,25538,0,0,900,54000,0,0,270,5546,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,207:7:0 0,15,157:5:0 0,9,117:3:0 +17 2524 . C 0 . DP=16;I16=5,9,0,0,548,23502,0,0,840,50400,0,0,256,5342,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,182:6:0 0,15,156:5:0 0,9,112:3:0 +17 2525 . A C, 0 . DP=17;I16=6,9,0,1,550,23138,28,784,900,54000,60,3600,248,5174,12,144;QS=2.86,0.14,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,24,168,24,168,168:8:0 13,0,138,25,141,159:5:1 0,9,117,9,117,117:3:0 +17 2526 . C 0 . DP=18;I16=6,11,0,0,677,28649,0,0,1020,61200,0,0,256,5232,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,229:9:0 0,15,183:5:0 0,9,113:3:0 +17 2527 . T 0 . DP=18;I16=6,11,0,0,674,29286,0,0,1020,61200,0,0,252,5118,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,217:9:0 0,15,183:5:0 0,9,119:3:0 +17 2528 . G 0 . DP=18;I16=6,11,0,0,701,30729,0,0,1020,61200,0,0,248,5028,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,234:9:0 0,15,184:5:0 0,9,119:3:0 +17 2529 . C 0 . DP=18;I16=6,11,0,0,676,28974,0,0,1020,61200,0,0,244,4962,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,15,175:5:0 0,9,117:3:0 +17 2530 . A 0 . DP=18;I16=6,10,0,0,624,26620,0,0,960,57600,0,0,223,4631,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,209:9:0 0,12,153:4:0 0,9,116:3:0 +17 2531 . T 0 . DP=17;I16=6,10,0,0,641,27911,0,0,960,57600,0,0,236,4852,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,210:8:0 0,15,175:5:0 0,9,122:3:0 +17 2532 . T 0 . DP=17;I16=6,10,0,0,634,27460,0,0,960,57600,0,0,230,4708,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,212:8:0 0,15,173:5:0 0,9,117:3:0 +17 2533 . C 0 . DP=18;I16=6,11,0,0,614,24196,0,0,1020,61200,0,0,224,4588,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,212:9:0 0,15,159:5:0 0,9,104:3:0 +17 2534 . C 0 . DP=16;I16=5,10,0,0,595,25141,0,0,900,54000,0,0,221,4491,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,202:8:0 0,12,144:4:0 0,9,110:3:0 +17 2535 . A 0 . DP=16;I16=5,10,0,0,617,27711,0,0,900,54000,0,0,218,4416,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,204:8:0 0,12,136:4:0 0,9,123:3:0 +17 2536 . G 0 . DP=15;I16=4,10,0,0,543,23023,0,0,840,50400,0,0,216,4362,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,195:8:0 0,9,102:3:0 0,9,117:3:0 +17 2537 . C 0 . DP=15;I16=4,10,0,0,555,24075,0,0,840,50400,0,0,213,4279,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,195:8:0 0,9,113:3:0 0,9,115:3:0 +17 2538 . C 0 . DP=15;I16=5,9,0,0,510,21070,0,0,840,50400,0,0,211,4217,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,157:7:0 0,9,129:3:0 0,12,126:4:0 +17 2539 . C 0 . DP=15;I16=5,9,0,0,464,16896,0,0,840,50400,0,0,209,4125,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,146:7:0 0,9,122:3:0 0,12,111:4:0 +17 2540 . G 0 . DP=16;I16=6,9,0,0,548,21860,0,0,900,54000,0,0,207,4053,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,189:7:0 0,12,139:4:0 0,12,110:4:0 +17 2541 . G 0 . DP=15;I16=5,9,0,0,535,22527,0,0,840,50400,0,0,207,4001,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,170:7:0 0,9,117:3:0 0,12,140:4:0 +17 2542 . T 0 . DP=15;I16=4,9,0,0,527,23207,0,0,780,46800,0,0,203,3953,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,183:7:0 0,9,125:3:0 0,9,109:3:0 +17 2543 . G 0 . DP=15;I16=5,9,0,0,540,23004,0,0,840,50400,0,0,207,3957,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,196:7:0 0,9,117:3:0 0,12,117:4:0 +17 2544 . A 0 . DP=16;I16=6,9,0,0,569,24139,0,0,900,54000,0,0,207,3965,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,202:8:0 0,9,119:3:0 0,12,132:4:0 +17 2545 . C 0 . DP=16;I16=6,9,0,0,583,24657,0,0,900,54000,0,0,208,3994,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,217:8:0 0,9,118:3:0 0,12,130:4:0 +17 2546 . A 0 . DP=16;I16=6,9,0,0,608,27290,0,0,900,54000,0,0,209,4045,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,206:8:0 0,9,133:3:0 0,12,144:4:0 +17 2547 . G 0 . DP=16;I16=6,9,0,0,597,26215,0,0,900,54000,0,0,211,4117,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,191:7:0 0,9,131:3:0 0,15,150:5:0 +17 2548 . A 0 . DP=16;I16=6,9,0,0,632,28806,0,0,900,54000,0,0,214,4210,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,196:7:0 0,9,131:3:0 0,15,171:5:0 +17 2549 . G 0 . DP=16;I16=6,9,0,0,594,25254,0,0,900,54000,0,0,217,4325,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,180:7:0 0,9,132:3:0 0,15,160:5:0 +17 2550 . T 0 . DP=16;I16=6,9,0,0,572,24134,0,0,900,54000,0,0,219,4413,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,182:7:0 0,9,122:3:0 0,15,148:5:0 +17 2551 . G 0 . DP=16;I16=6,9,0,0,578,24606,0,0,900,54000,0,0,220,4474,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,181:7:0 0,9,131:3:0 0,15,151:5:0 +17 2552 . A 0 . DP=15;I16=6,8,0,0,585,26419,0,0,840,50400,0,0,221,4505,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,178:6:0 0,9,129:3:0 0,15,168:5:0 +17 2553 . G 0 . DP=15;I16=6,8,0,0,528,21944,0,0,840,50400,0,0,222,4554,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,170:6:0 0,9,117:3:0 0,15,142:5:0 +17 2554 . T 0 . DP=15;I16=6,8,0,0,543,23015,0,0,840,50400,0,0,223,4621,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,156:6:0 0,9,129:3:0 0,15,160:5:0 +17 2555 . C 0 . DP=15;I16=6,8,0,0,566,24416,0,0,840,50400,0,0,224,4706,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,173:6:0 0,9,131:3:0 0,15,159:5:0 +17 2556 . A 0 . DP=14;I16=6,7,0,0,487,20095,0,0,780,46800,0,0,226,4808,0,0;QS=3,0;MQSB=0.961166;MQ0F=0 PL:DP:DV 0,15,141:5:0 0,9,125:3:0 0,15,146:5:0 +17 2557 . C 0 . DP=13;I16=5,8,0,0,471,17481,0,0,780,46800,0,0,249,5325,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,161:5:0 0,9,96:3:0 0,15,151:5:0 +17 2558 . T 0 . DP=14;I16=5,9,0,0,535,20597,0,0,840,50400,0,0,251,5417,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,173:6:0 0,9,99:3:0 0,15,174:5:0 +17 2559 . G 0 . DP=14;I16=5,9,0,0,509,18693,0,0,840,50400,0,0,253,5475,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,172:6:0 0,9,98:3:0 0,15,156:5:0 +17 2560 . T 0 . DP=14;I16=5,9,0,0,489,17587,0,0,840,50400,0,0,255,5549,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,160:6:0 0,9,106:3:0 0,15,144:5:0 +17 2561 . C 0 . DP=14;I16=5,9,0,0,489,17477,0,0,840,50400,0,0,257,5639,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,164:6:0 0,9,96:3:0 0,15,153:5:0 +17 2562 . T 0 . DP=13;I16=5,8,0,0,460,17016,0,0,780,46800,0,0,260,5744,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,139:5:0 0,9,99:3:0 0,15,167:5:0 +17 2563 . C 0 . DP=14;I16=5,8,0,0,433,15133,0,0,780,46800,0,0,263,5863,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,149:5:0 0,9,83:3:0 0,15,142:5:0 +17 2564 . A G, 0 . DP=15;I16=1,4,4,5,174,6124,316,11352,300,18000,540,32400,61,1311,184,4034;QS=0.988263,2.01174,0;VDB=0.690812;SGB=-3.20711;RPB=0.197899;MQB=1;MQSB=1;BQB=0.965069;MQ0F=0 PL:DP:DV 88,0,78,98,87,171:6:3 57,0,56,63,62,117:4:2 124,12,0,124,12,124:4:4 +17 2565 . A 0 . DP=15;I16=6,9,0,0,562,21216,0,0,900,54000,0,0,274,6076,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,178:6:0 0,12,134:4:0 0,15,166:5:0 +17 2566 . A 0 . DP=15;I16=6,9,0,0,545,20019,0,0,900,54000,0,0,276,6098,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,181:6:0 0,12,120:4:0 0,15,162:5:0 +17 2567 . A 0 . DP=16;I16=7,9,0,0,580,21342,0,0,960,57600,0,0,278,6136,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,177:6:0 0,15,151:5:0 0,15,166:5:0 +17 2568 . A 0 . DP=16;I16=7,8,0,0,555,20795,0,0,900,54000,0,0,256,5566,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,180:6:0 0,12,132:4:0 0,15,167:5:0 +17 2569 . A 0 . DP=17;I16=7,10,0,0,661,25943,0,0,1020,61200,0,0,284,6264,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,213:7:0 0,15,163:5:0 0,15,172:5:0 +17 2570 . G 0 . DP=18;I16=8,10,0,0,664,24968,0,0,1080,64800,0,0,287,6305,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,213:7:0 0,15,152:5:0 0,18,176:6:0 +17 2571 . A 0 . DP=18;I16=8,10,0,0,618,21870,0,0,1080,64800,0,0,291,6365,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,195:7:0 0,15,155:5:0 0,18,155:6:0 +17 2572 . A 0 . DP=18;I16=8,10,0,0,631,22829,0,0,1080,64800,0,0,295,6445,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,194:7:0 0,15,150:5:0 0,18,173:6:0 +17 2573 . A 0 . DP=18;I16=8,10,0,0,690,26830,0,0,1080,64800,0,0,298,6494,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,210:7:0 0,15,170:5:0 0,18,183:6:0 +17 2574 . G 0 . DP=18;I16=8,10,0,0,664,24884,0,0,1080,64800,0,0,301,6561,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,211:7:0 0,15,152:5:0 0,18,176:6:0 +17 2575 . G 0 . DP=18;I16=8,10,0,0,642,23904,0,0,1080,64800,0,0,305,6645,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,242:8:0 0,15,145:5:0 0,15,140:5:0 +17 2576 . A 0 . DP=18;I16=7,10,0,0,595,21311,0,0,1020,61200,0,0,285,6121,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,210:8:0 0,15,153:5:0 0,12,131:4:0 +17 2577 . A 0 . DP=19;I16=8,10,0,0,682,26398,0,0,1080,64800,0,0,290,6240,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,244:8:0 0,15,161:5:0 0,15,155:5:0 +17 2578 . G 0 . DP=18;I16=9,9,0,0,643,24115,0,0,1080,64800,0,0,322,7002,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,249:8:0 0,12,114:4:0 0,18,161:6:0 +17 2579 . A 0 . DP=18;I16=9,8,0,0,634,23870,0,0,1020,61200,0,0,304,6532,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,229:8:0 0,9,110:3:0 0,18,176:6:0 +17 2580 . A 0 . DP=18;I16=9,9,0,0,629,22593,0,0,1080,64800,0,0,336,7330,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,223:8:0 0,12,117:4:0 0,18,169:6:0 +17 2581 . A 0 . DP=19;I16=10,9,0,0,691,25669,0,0,1140,68400,0,0,343,7521,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,12,133:4:0 0,18,166:6:0 +17 2582 . T 0 . DP=19;I16=10,9,0,0,674,24218,0,0,1140,68400,0,0,350,7682,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,235:9:0 0,12,138:4:0 0,18,168:6:0 +17 2583 . A 0 . DP=19;I16=10,9,0,0,693,25465,0,0,1140,68400,0,0,357,7865,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,247:9:0 0,12,126:4:0 0,18,178:6:0 +17 2584 . A 0 . DP=19;I16=10,9,0,0,702,26340,0,0,1140,68400,0,0,363,8019,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,243:9:0 0,12,134:4:0 0,18,187:6:0 +17 2585 . A 0 . DP=19;I16=9,9,0,0,690,26700,0,0,1080,64800,0,0,350,7818,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,250:9:0 0,9,114:3:0 0,18,190:6:0 +17 2586 . G 0 . DP=19;I16=10,9,0,0,714,27314,0,0,1140,68400,0,0,373,8283,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,12,127:4:0 0,18,176:6:0 +17 2587 . A 0 . DP=20;I16=9,9,0,0,665,24781,0,0,1049,62041,0,0,343,7717,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,137:4:0 0,12,136:4:0 +17 2588 . A 0 . DP=21;I16=12,9,0,0,737,26531,0,0,1229,72841,0,0,384,8620,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,138:4:0 0,18,162:6:0 +17 2589 . A 0 . DP=22;I16=13,9,0,0,780,28412,0,0,1289,76441,0,0,390,8770,0,0;QS=3,0;MQSB=0.955854;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,142:4:0 0,18,170:6:0 +17 2590 . A 0 . DP=22;I16=13,9,0,0,774,28352,0,0,1289,76441,0,0,396,8894,0,0;QS=3,0;MQSB=0.955854;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,135:4:0 0,18,160:6:0 +17 2591 . C 0 . DP=21;I16=13,8,0,0,765,28617,0,0,1229,72841,0,0,403,9041,0,0;QS=3,0;MQSB=0.95891;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,136:4:0 0,15,136:5:0 +17 2592 . A 0 . DP=21;I16=13,8,0,0,763,28325,0,0,1229,72841,0,0,410,9210,0,0;QS=3,0;MQSB=0.95891;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,140:4:0 0,15,139:5:0 +17 2593 . A 0 . DP=21;I16=13,8,0,0,754,27888,0,0,1229,72841,0,0,416,9350,0,0;QS=3,0;MQSB=0.95891;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,141:4:0 0,15,147:5:0 +17 2594 . A 0 . DP=21;I16=13,8,0,0,775,29179,0,0,1229,72841,0,0,422,9510,0,0;QS=3,0;MQSB=0.95891;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,130:4:0 0,15,153:5:0 +17 2595 . T 0 . DP=22;I16=14,8,0,0,766,27472,0,0,1289,76441,0,0,427,9639,0,0;QS=3,0;MQSB=0.963419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,119:4:0 0,15,143:5:0 +17 2596 . A 0 . DP=22;I16=13,8,0,0,751,27409,0,0,1229,72841,0,0,407,9111,0,0;QS=3,0;MQSB=0.95891;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,123:4:0 0,12,129:4:0 +17 2597 . A 0 . DP=22;I16=14,8,0,0,811,30147,0,0,1289,76441,0,0,437,9851,0,0;QS=3,0;MQSB=0.963419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,145:4:0 0,15,145:5:0 +17 2598 . A 0 . DP=22;I16=14,8,0,0,817,30915,0,0,1289,76441,0,0,442,9984,0,0;QS=3,0;MQSB=0.963419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,136:4:0 0,15,159:5:0 +17 2599 . A 0 . DP=22;I16=14,8,0,0,800,29912,0,0,1289,76441,0,0,447,10135,0,0;QS=3,0;MQSB=0.963419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,126:4:0 0,15,150:5:0 +17 2600 . A 0 . DP=22;I16=14,8,0,0,784,29138,0,0,1289,76441,0,0,451,10255,0,0;QS=3,0;MQSB=0.963419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,113:4:0 0,15,150:5:0 +17 2601 . T 0 . DP=22;I16=14,8,0,0,770,27820,0,0,1289,76441,0,0,454,10344,0,0;QS=3,0;MQSB=0.963419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,118:4:0 0,15,142:5:0 +17 2602 . A 0 . DP=23;I16=15,8,0,0,825,29971,0,0,1349,80041,0,0,457,10451,0,0;QS=3,0;MQSB=0.967216;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,143:4:0 0,18,154:6:0 +17 2603 . A 0 . DP=23;I16=15,8,0,0,862,32840,0,0,1349,80041,0,0,460,10526,0,0;QS=3,0;MQSB=0.967216;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,138:4:0 0,18,172:6:0 +17 2604 . T 0 . DP=23;I16=15,8,0,0,822,29902,0,0,1349,80041,0,0,463,10619,0,0;QS=3,0;MQSB=0.967216;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,129:4:0 0,18,154:6:0 +17 2605 . A 0 . DP=23;I16=14,8,0,0,845,32617,0,0,1289,76441,0,0,441,10105,0,0;QS=3,0;MQSB=0.963419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,143:4:0 0,15,157:5:0 +17 2606 . G 0 . DP=23;I16=14,8,0,0,812,30796,0,0,1289,76441,0,0,444,10234,0,0;QS=3,0;MQSB=0.963419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,129:4:0 0,15,142:5:0 +17 2607 . T 0 . DP=22;I16=15,7,0,0,782,28440,0,0,1289,76441,0,0,472,10954,0,0;QS=3,0;MQSB=0.970024;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,119:4:0 0,15,132:5:0 +17 2608 . G 0 . DP=22;I16=15,7,0,0,851,33169,0,0,1289,76441,0,0,474,11014,0,0;QS=3,0;MQSB=0.970024;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,132:4:0 0,15,127:5:0 +17 2609 . C 0 . DP=22;I16=15,7,0,0,796,29454,0,0,1289,76441,0,0,475,11041,0,0;QS=3,0;MQSB=0.970024;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,137:4:0 0,15,124:5:0 +17 2610 . A 0 . DP=22;I16=15,7,0,0,830,31684,0,0,1289,76441,0,0,476,11086,0,0;QS=3,0;MQSB=0.970024;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,146:4:0 0,15,121:5:0 +17 2611 . G 0 . DP=22;I16=15,7,0,0,824,32048,0,0,1289,76441,0,0,477,11149,0,0;QS=3,0;MQSB=0.970024;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,129:4:0 0,15,122:5:0 +17 2612 . A 0 . DP=22;I16=14,7,0,0,771,29035,0,0,1229,72841,0,0,453,10605,0,0;QS=3,0;MQSB=0.966484;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,130:4:0 0,12,117:4:0 +17 2613 . C 0 . DP=22;I16=15,7,0,0,832,31926,0,0,1289,76441,0,0,478,11278,0,0;QS=3,0;MQSB=0.970024;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,138:4:0 0,15,120:5:0 +17 2614 . A 0 . DP=21;I16=15,6,0,0,791,30065,0,0,1229,72841,0,0,477,11241,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,110:3:0 0,15,140:5:0 +17 2615 . A 0 . DP=21;I16=15,6,0,0,777,29101,0,0,1229,72841,0,0,475,11167,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,99:3:0 0,15,142:5:0 +17 2616 . A 0 . DP=21;I16=15,6,0,0,734,26922,0,0,1229,72841,0,0,472,11056,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,90:3:0 0,15,144:5:0 +17 2617 . A 0 . DP=21;I16=15,6,0,0,810,31654,0,0,1229,72841,0,0,469,10959,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,95:3:0 0,15,140:5:0 +17 2618 . G 0 . DP=23;I16=16,6,0,0,863,34219,0,0,1289,76441,0,0,441,10251,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,74:2:0 0,15,132:5:0 +17 2619 . G 0 . DP=23;I16=16,6,0,0,807,30109,0,0,1289,76441,0,0,439,10135,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,66:2:0 0,15,127:5:0 +17 2620 . C 0 . DP=23;I16=16,7,0,0,780,28242,0,0,1349,80041,0,0,462,10664,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,87:3:0 0,15,115:5:0 +17 2621 . C 0 . DP=23;I16=16,7,0,0,860,32944,0,0,1349,80041,0,0,459,10537,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,112:3:0 0,15,124:5:0 +17 2622 . T 0 . DP=24;I16=17,7,0,0,908,35474,0,0,1409,83641,0,0,456,10428,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,115:3:0 0,15,134:5:0 +17 2623 . T 0 . DP=24;I16=17,7,0,0,850,30978,0,0,1409,83641,0,0,453,10289,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,114:3:0 0,15,129:5:0 +17 2624 . G 0 . DP=24;I16=17,7,0,0,882,33332,0,0,1409,83641,0,0,450,10172,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,101:3:0 0,15,133:5:0 +17 2625 . A 0 . DP=23;I16=17,6,0,0,855,32593,0,0,1349,80041,0,0,448,10076,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,114:3:0 0,15,135:5:0 +17 2626 . C 0 . DP=23;I16=17,6,0,0,847,31625,0,0,1349,80041,0,0,446,10000,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,100:3:0 0,15,122:5:0 +17 2627 . C 0 . DP=23;I16=17,6,0,0,863,32865,0,0,1349,80041,0,0,444,9944,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,104:3:0 0,15,129:5:0 +17 2628 . C 0 . DP=24;I16=17,6,0,0,793,28559,0,0,1349,80041,0,0,431,9757,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,95:3:0 0,15,127:5:0 +17 2629 . A 0 . DP=24;I16=18,6,0,0,893,33537,0,0,1409,83641,0,0,439,9789,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,101:3:0 0,18,148:6:0 +17 2630 . T 0 . DP=24;I16=17,6,0,0,836,31094,0,0,1380,82800,0,0,412,9116,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,112:3:0 0,18,140:6:0 +17 2631 . C 0 . DP=24;I16=18,6,0,0,900,34378,0,0,1409,83641,0,0,435,9713,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,104:3:0 0,18,142:6:0 +17 2632 . T 0 . DP=24;I16=18,6,0,0,937,37097,0,0,1409,83641,0,0,433,9705,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,113:3:0 0,18,164:6:0 +17 2633 . A 0 . DP=23;I16=18,5,0,0,801,28913,0,0,1349,80041,0,0,431,9667,0,0;QS=3,0;MQSB=0.982789;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,95:3:0 0,18,148:6:0 +17 2634 . G 0 . DP=23;I16=19,3,0,0,861,34125,0,0,1289,76441,0,0,405,9023,0,0;QS=3,0;MQSB=0.989755;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,74:2:0 0,18,149:6:0 +17 2635 . C 0 . DP=23;I16=19,4,0,0,848,32154,0,0,1349,80041,0,0,429,9599,0,0;QS=3,0;MQSB=0.986928;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,107:3:0 0,18,148:6:0 +17 2636 . T 0 . DP=24;I16=19,4,0,0,871,33973,0,0,1349,80041,0,0,428,9572,0,0;QS=3,0;MQSB=0.986928;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,98:3:0 0,18,160:6:0 +17 2637 . T 0 . DP=24;I16=19,5,0,0,871,32073,0,0,1409,83641,0,0,428,9568,0,0;QS=3,0;MQSB=0.984335;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,111:3:0 0,18,144:6:0 +17 2638 . T 0 . DP=24;I16=19,5,0,0,821,28851,0,0,1409,83641,0,0,428,9588,0,0;QS=3,0;MQSB=0.984335;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,103:3:0 0,18,135:6:0 +17 2639 . G 0 . DP=24;I16=18,6,0,0,842,30840,0,0,1409,83641,0,0,428,9582,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,106:3:0 0,15,125:5:0 +17 2640 . G 0 . DP=24;I16=17,6,0,0,749,25957,0,0,1380,82800,0,0,404,8976,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,84:3:0 0,15,117:5:0 +17 2641 . C 0 . DP=23;I16=17,6,0,0,834,31792,0,0,1349,80041,0,0,431,9645,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,61:2:0 0,15,129:5:0 +17 2642 . C 0 . DP=23;I16=17,6,0,0,809,30033,0,0,1349,80041,0,0,433,9713,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,58:2:0 0,15,131:5:0 +17 2643 . C 0 . DP=23;I16=17,6,0,0,856,33004,0,0,1349,80041,0,0,434,9756,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,57:2:0 0,15,133:5:0 +17 2644 . T 0 . DP=22;I16=16,5,0,0,805,31419,0,0,1229,72841,0,0,428,9648,0,0;QS=3,0;MQSB=0.978919;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,73:2:0 0,15,143:5:0 +17 2645 . C 0 . DP=22;I16=15,6,0,0,823,32499,0,0,1229,72841,0,0,415,9323,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,78:2:0 0,12,122:4:0 +17 2646 . A 0 . DP=22;I16=16,6,0,0,826,31566,0,0,1289,76441,0,0,430,9524,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,79:2:0 0,15,129:5:0 +17 2647 . G 0 . DP=22;I16=16,6,0,0,803,30643,0,0,1289,76441,0,0,428,9460,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,77:2:0 0,15,129:5:0 +17 2648 . C 0 . DP=21;I16=15,6,0,0,811,31709,0,0,1229,72841,0,0,426,9368,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,80:2:0 0,12,118:4:0 +17 2649 . A 0 . DP=23;I16=16,6,0,0,789,29215,0,0,1258,73682,0,0,414,9196,0,0;QS=3,0;MQSB=0.934321;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,93:3:0 0,12,105:4:0 +17 2650 . T 0 . DP=23;I16=16,7,0,0,856,32340,0,0,1318,77282,0,0,423,9197,0,0;QS=3,0;MQSB=0.955805;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,103:3:0 0,12,118:4:0 +17 2651 . C 0 . DP=23;I16=16,7,0,0,871,33599,0,0,1318,77282,0,0,422,9124,0,0;QS=3,0;MQSB=0.955805;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,95:3:0 0,12,121:4:0 +17 2652 . A 0 . DP=23;I16=16,7,0,0,820,30324,0,0,1318,77282,0,0,421,9077,0,0;QS=3,0;MQSB=0.955805;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,87:3:0 0,12,126:4:0 +17 2653 . A 0 . DP=23;I16=15,6,0,0,759,28489,0,0,1198,70082,0,0,389,8395,0,0;QS=3,0;MQSB=0.940481;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,73:2:0 0,9,109:3:0 +17 2654 . C 0 . DP=23;I16=16,7,0,0,836,31006,0,0,1318,77282,0,0,393,8385,0,0;QS=3,0;MQSB=0.955805;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,88:3:0 0,9,99:3:0 +17 2655 . C 0 . DP=23;I16=16,7,0,0,774,27190,0,0,1318,77282,0,0,392,8364,0,0;QS=3,0;MQSB=0.955805;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,83:3:0 0,9,95:3:0 +17 2656 . G 0 . DP=24;I16=17,7,0,0,781,25689,0,0,1378,80882,0,0,390,8320,0,0;QS=3,0;MQSB=0.95083;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,116:4:0 0,9,74:3:0 +17 2657 . C 0 . DP=24;I16=17,6,0,0,871,33435,0,0,1349,80041,0,0,381,8241,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,98:3:0 0,9,99:3:0 +17 2658 . T 0 . DP=23;I16=17,6,0,0,897,35255,0,0,1318,77282,0,0,389,8319,0,0;QS=3,0;MQSB=0.92854;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,133:4:0 0,9,107:3:0 +17 2659 . A 0 . DP=23;I16=17,6,0,0,817,29729,0,0,1318,77282,0,0,389,8361,0,0;QS=3,0;MQSB=0.92854;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,120:4:0 0,9,93:3:0 +17 2660 . G 0 . DP=23;I16=17,6,0,0,900,35462,0,0,1318,77282,0,0,389,8379,0,0;QS=3,0;MQSB=0.92854;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,126:4:0 0,9,94:3:0 +17 2661 . A 0 . DP=24;I16=18,6,0,0,871,32185,0,0,1378,80882,0,0,390,8422,0,0;QS=3,0;MQSB=0.923116;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,127:4:0 0,9,104:3:0 +17 2662 . T 0 . DP=24;I16=17,6,0,0,836,30812,0,0,1349,80041,0,0,366,7816,0,0;QS=3,0;MQSB=0.83771;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,122:4:0 0,9,99:3:0 +17 2663 . A 0 . DP=24;I16=17,6,0,0,827,30583,0,0,1318,77282,0,0,389,8341,0,0;QS=3,0;MQSB=0.92854;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,104:4:0 0,9,101:3:0 +17 2664 . C 0 . DP=23;I16=17,6,0,0,787,28083,0,0,1318,77282,0,0,388,8270,0,0;QS=3,0;MQSB=0.92854;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,107:4:0 0,9,91:3:0 +17 2665 . G 0 . DP=23;I16=17,6,0,0,728,23290,0,0,1318,77282,0,0,386,8178,0,0;QS=3,0;MQSB=0.92854;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,112:4:0 0,9,78:3:0 +17 2666 . T 0 . DP=23;I16=17,5,0,0,799,29273,0,0,1289,76441,0,0,367,7825,0,0;QS=3,0;MQSB=0.981001;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,105:3:0 0,9,94:3:0 +17 2667 . C 0 . DP=23;I16=16,5,0,0,792,30190,0,0,1260,75600,0,0,345,7393,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,96:3:0 0,9,98:3:0 +17 2668 . C 0 . DP=24;I16=18,6,0,0,832,29692,0,0,1378,80882,0,0,381,8069,0,0;QS=3,0;MQSB=0.923116;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,107:4:0 0,9,95:3:0 +17 2669 . C 0 . DP=23;I16=18,5,0,0,829,30953,0,0,1318,77282,0,0,383,8087,0,0;QS=3,0;MQSB=0.889264;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,120:4:0 0,9,88:3:0 +17 2670 . T 0 . DP=23;I16=17,5,0,0,841,32669,0,0,1289,76441,0,0,368,7828,0,0;QS=3,0;MQSB=0.801124;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,131:4:0 0,9,100:3:0 +17 2671 . C 0 . DP=22;I16=17,5,0,0,842,32448,0,0,1258,73682,0,0,386,8110,0,0;QS=3,0;MQSB=0.895399;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,128:4:0 0,6,70:2:0 +17 2672 . C 0 . DP=22;I16=17,5,0,0,808,30180,0,0,1258,73682,0,0,388,8164,0,0;QS=3,0;MQSB=0.895399;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,129:4:0 0,6,75:2:0 +17 2673 . C 0 . DP=22;I16=17,5,0,0,842,32528,0,0,1258,73682,0,0,390,8246,0,0;QS=3,0;MQSB=0.895399;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,133:4:0 0,6,75:2:0 +17 2674 . T 0 . DP=23;I16=17,6,0,0,860,33242,0,0,1318,77282,0,0,392,8356,0,0;QS=3,0;MQSB=0.92854;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,142:4:0 0,6,79:2:0 +17 2675 . T 0 . DP=22;I16=16,6,0,0,756,26986,0,0,1258,73682,0,0,394,8392,0,0;QS=3,0;MQSB=0.934321;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,134:4:0 0,6,74:2:0 +17 2676 . T 0 . DP=22;I16=16,6,0,0,774,28022,0,0,1258,73682,0,0,396,8452,0,0;QS=3,0;MQSB=0.934321;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,135:4:0 0,6,75:2:0 +17 2677 . C 0 . DP=22;I16=16,6,0,0,866,34444,0,0,1258,73682,0,0,398,8536,0,0;QS=3,0;MQSB=0.934321;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,131:4:0 0,6,77:2:0 +17 2678 . T 0 . DP=22;I16=16,5,0,0,818,32216,0,0,1229,72841,0,0,374,7970,0,0;QS=3,0;MQSB=0.978919;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,111:3:0 0,6,80:2:0 +17 2679 . T 0 . DP=22;I16=16,6,0,0,808,29912,0,0,1258,73682,0,0,400,8680,0,0;QS=3,0;MQSB=0.934321;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,137:4:0 0,6,75:2:0 +17 2680 . C 0 . DP=23;I16=16,7,0,0,873,33605,0,0,1318,77282,0,0,400,8740,0,0;QS=3,0;MQSB=0.955805;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,131:4:0 0,6,70:2:0 +17 2681 . T 0 . DP=22;I16=15,7,0,0,820,31248,0,0,1258,73682,0,0,402,8824,0,0;QS=3,0;MQSB=0.961028;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,133:4:0 0,6,75:2:0 +17 2682 . G 0 . DP=22;I16=15,7,0,0,831,31865,0,0,1258,73682,0,0,403,8881,0,0;QS=3,0;MQSB=0.961028;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,135:4:0 0,6,64:2:0 +17 2683 . G 0 . DP=22;I16=13,6,0,0,702,26368,0,0,1109,65641,0,0,394,8926,0,0;QS=3,0;MQSB=0.850016;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,136:4:0 0,6,53:2:0 +17 2684 . G 0 . DP=22;I16=14,7,0,0,754,27678,0,0,1229,72841,0,0,403,9057,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,128:4:0 0,6,62:2:0 +17 2685 . G 0 . DP=22;I16=15,7,0,0,736,25916,0,0,1258,73682,0,0,406,9184,0,0;QS=3,0;MQSB=0.961028;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,130:4:0 0,6,45:2:0 +17 2686 . C 0 . DP=22;I16=15,7,0,0,803,29933,0,0,1258,73682,0,0,406,9278,0,0;QS=3,0;MQSB=0.961028;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,134:4:0 0,6,68:2:0 +17 2687 . A 0 . DP=21;I16=13,7,0,0,716,26356,0,0,1169,69241,0,0,406,9340,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,136:4:0 0,6,61:2:0 +17 2688 . C 0 . DP=20;I16=13,7,0,0,750,28308,0,0,1169,69241,0,0,407,9417,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,134:4:0 0,6,66:2:0 +17 2689 . A 0 . DP=19;I16=12,7,0,0,741,29105,0,0,1109,65641,0,0,409,9507,0,0;QS=3,0;MQSB=0.879351;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,140:4:0 0,6,73:2:0 +17 2690 . G 0 . DP=20;I16=12,8,0,0,751,28929,0,0,1169,69241,0,0,411,9609,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,135:4:0 0,6,61:2:0 +17 2691 . G 0 . DP=20;I16=12,7,0,0,682,25006,0,0,1109,65641,0,0,403,9603,0,0;QS=3,0;MQSB=0.879351;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,132:4:0 0,6,63:2:0 +17 2692 . T 0 . DP=20;I16=12,8,0,0,648,21758,0,0,1169,69241,0,0,417,9853,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,125:4:0 0,6,72:2:0 +17 2693 . C 0 . DP=20;I16=12,8,0,0,779,30645,0,0,1169,69241,0,0,418,9898,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,130:4:0 0,6,70:2:0 +17 2694 . A 0 . DP=21;I16=13,8,0,0,723,25649,0,0,1229,72841,0,0,417,9859,0,0;QS=3,0;MQSB=0.895122;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,126:4:0 0,6,73:2:0 +17 2695 . C 0 . DP=20;I16=12,8,0,0,757,28835,0,0,1169,69241,0,0,418,9834,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,130:4:0 0,6,63:2:0 +17 2696 . A 0 . DP=20;I16=12,8,0,0,733,27357,0,0,1169,69241,0,0,419,9823,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,130:4:0 0,6,69:2:0 +17 2697 . C 0 . DP=20;I16=12,8,0,0,738,27604,0,0,1169,69241,0,0,419,9777,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,128:4:0 0,6,66:2:0 +17 2698 . T 0 . DP=21;I16=12,8,0,0,788,31268,0,0,1169,69241,0,0,419,9747,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,144:4:0 0,6,77:2:0 +17 2699 . C 0 . DP=22;I16=13,9,0,0,864,34148,0,0,1258,73682,0,0,443,10309,0,0;QS=3,0;MQSB=0.686045;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,135:4:0 0,9,98:3:0 +17 2700 . T 0 . DP=22;I16=13,9,0,0,850,33296,0,0,1258,73682,0,0,444,10310,0,0;QS=3,0;MQSB=0.686045;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,141:4:0 0,9,105:3:0 +17 2701 . C 0 . DP=22;I16=13,9,0,0,863,34157,0,0,1258,73682,0,0,444,10278,0,0;QS=3,0;MQSB=0.686045;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,140:4:0 0,9,94:3:0 +17 2702 . T 0 . DP=22;I16=13,9,0,0,837,32525,0,0,1258,73682,0,0,444,10262,0,0;QS=3,0;MQSB=0.686045;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,143:4:0 0,9,83:3:0 +17 2703 . T 0 . DP=21;I16=12,8,0,0,717,25881,0,0,1169,69241,0,0,420,9636,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,130:4:0 0,3,32:1:0 +17 2704 . C 0 . DP=21;I16=12,9,0,0,794,30766,0,0,1198,70082,0,0,445,10225,0,0;QS=3,0;MQSB=0.695144;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,137:4:0 0,6,55:2:0 +17 2705 . C 0 . DP=21;I16=12,9,0,0,809,31649,0,0,1198,70082,0,0,445,10205,0,0;QS=3,0;MQSB=0.695144;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,136:4:0 0,6,56:2:0 +17 2706 . A 0 . DP=22;I16=12,10,0,0,820,31386,0,0,1258,73682,0,0,444,10150,0,0;QS=3,0;MQSB=0.731218;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,141:4:0 0,6,70:2:0 +17 2707 . G 0 . DP=22;I16=12,10,0,0,832,32104,0,0,1258,73682,0,0,444,10110,0,0;QS=3,0;MQSB=0.731218;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,139:4:0 0,6,60:2:0 +17 2708 . G 0 . DP=22;I16=12,10,0,0,777,28329,0,0,1258,73682,0,0,444,10086,0,0;QS=3,0;MQSB=0.731218;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,136:4:0 0,6,57:2:0 +17 2709 . T 0 . DP=22;I16=12,9,0,0,761,28341,0,0,1229,72841,0,0,418,9404,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,137:4:0 0,3,39:1:0 +17 2710 . C 0 . DP=23;I16=12,10,0,0,840,32478,0,0,1289,76441,0,0,417,9365,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,134:4:0 0,3,38:1:0 +17 2711 . T 0 . DP=24;I16=13,11,0,0,893,33721,0,0,1378,80882,0,0,442,9970,0,0;QS=3,0;MQSB=0.75304;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,138:4:0 0,6,72:2:0 +17 2712 . A 0 . DP=24;I16=13,11,0,0,889,33333,0,0,1378,80882,0,0,443,9971,0,0;QS=3,0;MQSB=0.75304;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,141:4:0 0,6,65:2:0 +17 2713 . G T, 0 . DP=25;I16=13,11,0,1,915,35485,14,196,1378,80882,29,841,419,9369,25,625;QS=2.72549,0.27451,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.569783;BQB=1;MQ0F=0 PL:DP:DV 0,57,255,57,255,255:19:0 0,12,131,12,131,131:4:0 8,0,31,11,34,42:2:1 +17 2714 . G 0 . DP=25;I16=13,11,0,0,891,33457,0,0,1378,80882,0,0,444,9990,0,0;QS=3,0;MQSB=0.75304;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,132:4:0 0,6,64:2:0 +17 2715 . A 0 . DP=25;I16=13,12,0,0,888,32012,0,0,1407,81723,0,0,446,10014,0,0;QS=3,0;MQSB=0.569783;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,12,135:4:0 0,6,63:2:0 +17 2716 . T 0 . DP=26;I16=13,13,0,0,937,34241,0,0,1467,85323,0,0,446,10012,0,0;QS=3,0;MQSB=0.606531;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,12,134:4:0 0,9,90:3:0 +17 2717 . G 0 . DP=26;I16=13,12,0,0,939,35995,0,0,1438,84482,0,0,422,9410,0,0;QS=3,0;MQSB=0.778801;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,12,134:4:0 0,6,72:2:0 +17 2718 . C 0 . DP=24;I16=12,11,0,0,864,33118,0,0,1318,77282,0,0,425,9457,0,0;QS=3,0;MQSB=0.7613;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,130:4:0 0,6,65:2:0 +17 2719 . A 0 . DP=24;I16=12,12,0,0,911,35371,0,0,1347,78123,0,0,452,10102,0,0;QS=3,0;MQSB=0.582748;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,139:4:0 0,9,99:3:0 +17 2720 . G 0 . DP=24;I16=12,12,0,0,940,37044,0,0,1347,78123,0,0,453,10095,0,0;QS=3,0;MQSB=0.582748;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,136:4:0 0,9,97:3:0 +17 2721 . C 0 . DP=24;I16=12,11,0,0,881,34499,0,0,1318,77282,0,0,429,9485,0,0;QS=3,0;MQSB=0.7613;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,131:4:0 0,6,76:2:0 +17 2722 . T 0 . DP=24;I16=11,13,0,0,898,34310,0,0,1347,78123,0,0,456,10146,0,0;QS=3,0;MQSB=0.633229;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,156:5:0 0,9,98:3:0 +17 2723 . G 0 . DP=25;I16=12,13,0,0,941,36257,0,0,1407,81723,0,0,459,10203,0,0;QS=3,0;MQSB=0.619223;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,184:6:0 0,9,76:3:0 +17 2724 . A 0 . DP=25;I16=12,13,0,0,917,34211,0,0,1407,81723,0,0,462,10234,0,0;QS=3,0;MQSB=0.619223;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,188:6:0 0,9,84:3:0 +17 2725 . G 0 . DP=25;I16=12,12,0,0,916,35656,0,0,1378,80882,0,0,438,9566,0,0;QS=3,0;MQSB=0.786628;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,185:6:0 0,6,67:2:0 +17 2726 . G 0 . DP=25;I16=11,12,0,0,841,31809,0,0,1287,74523,0,0,437,9545,0,0;QS=3,0;MQSB=0.597127;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,186:6:0 0,6,46:2:0 +17 2727 . G 0 . DP=25;I16=12,13,0,0,889,32233,0,0,1407,81723,0,0,464,10182,0,0;QS=3,0;MQSB=0.619223;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,194:7:0 0,6,56:2:0 +17 2728 . G 0 . DP=25;I16=12,13,0,0,883,32287,0,0,1407,81723,0,0,467,10219,0,0;QS=3,0;MQSB=0.619223;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,189:7:0 0,6,50:2:0 +17 2729 . T 0 . DP=25;I16=12,13,0,0,871,31019,0,0,1407,81723,0,0,469,10233,0,0;QS=3,0;MQSB=0.619223;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,189:7:0 0,6,62:2:0 +17 2730 . G 0 . DP=25;I16=12,13,0,0,907,34299,0,0,1407,81723,0,0,471,10275,0,0;QS=3,0;MQSB=0.619223;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,192:7:0 0,6,49:2:0 +17 2731 . C 0 . DP=25;I16=12,13,0,0,893,33027,0,0,1407,81723,0,0,473,10345,0,0;QS=3,0;MQSB=0.619223;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,192:7:0 0,6,52:2:0 +17 2732 . C 0 . DP=25;I16=12,13,0,0,882,32170,0,0,1407,81723,0,0,473,10343,0,0;QS=3,0;MQSB=0.619223;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,195:7:0 0,6,38:2:0 +17 2733 . C A, 0 . DP=25;I16=12,12,0,1,835,30063,13,169,1378,80882,29,841,448,9744,25,625;QS=2.64865,0.351351,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.619223;BQB=1;MQ0F=0 PL:DP:DV 0,48,255,48,255,255:16:0 0,21,187,21,187,187:7:0 7,0,18,10,21,28:2:1 +17 2734 . C 0 . DP=25;I16=12,12,0,0,890,33726,0,0,1378,80882,0,0,449,9797,0,0;QS=3,0;MQSB=0.786628;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,208:8:0 0,3,39:1:0 +17 2735 . T 0 . DP=26;I16=13,12,0,0,955,36875,0,0,1438,84482,0,0,451,9877,0,0;QS=3,0;MQSB=0.778801;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,228:8:0 0,3,41:1:0 +17 2736 . C 0 . DP=26;I16=13,11,0,0,921,35553,0,0,1409,83641,0,0,428,9308,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,220:8:0 0,3,33:1:0 +17 2737 . T 0 . DP=26;I16=13,13,0,0,967,36581,0,0,1467,85323,0,0,475,10403,0,0;QS=3,0;MQSB=0.606531;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,228:8:0 0,6,64:2:0 +17 2738 . T 0 . DP=26;I16=13,13,0,0,895,31873,0,0,1467,85323,0,0,474,10374,0,0;QS=3,0;MQSB=0.606531;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,201:8:0 0,6,47:2:0 +17 2739 . A 0 . DP=26;I16=13,12,0,0,871,31051,0,0,1407,81723,0,0,448,9698,0,0;QS=3,0;MQSB=0.569783;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,224:8:0 0,9,78:3:0 +17 2740 . C 0 . DP=26;I16=14,11,0,0,952,36456,0,0,1438,84482,0,0,448,9674,0,0;QS=3,0;MQSB=0.745495;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,216:8:0 0,6,71:2:0 +17 2741 . C 0 . DP=26;I16=14,11,0,0,945,36141,0,0,1438,84482,0,0,448,9678,0,0;QS=3,0;MQSB=0.745495;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,215:8:0 0,6,75:2:0 +17 2742 . A 0 . DP=27;I16=15,12,0,0,949,34263,0,0,1527,88923,0,0,472,10284,0,0;QS=3,0;MQSB=0.547344;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,230:9:0 0,9,92:3:0 +17 2743 . T 0 . DP=27;I16=15,12,0,0,955,34479,0,0,1527,88923,0,0,471,10243,0,0;QS=3,0;MQSB=0.547344;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,224:9:0 0,9,99:3:0 +17 2744 . C 0 . DP=26;I16=15,10,0,0,955,36951,0,0,1438,84482,0,0,445,9557,0,0;QS=3,0;MQSB=0.707404;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,234:9:0 0,6,76:2:0 +17 2745 . T 0 . DP=26;I16=15,11,0,0,962,36786,0,0,1467,85323,0,0,469,10151,0,0;QS=3,0;MQSB=0.505697;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,243:9:0 0,9,104:3:0 +17 2746 . A 0 . DP=26;I16=15,10,0,0,912,33536,0,0,1438,84482,0,0,443,9525,0,0;QS=3,0;MQSB=0.707404;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,235:9:0 0,6,78:2:0 +17 2747 . A 0 . DP=26;I16=15,11,0,0,945,35117,0,0,1467,85323,0,0,467,10179,0,0;QS=3,0;MQSB=0.505697;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,238:9:0 0,9,96:3:0 +17 2748 . T 0 . DP=27;I16=15,12,0,0,1005,37901,0,0,1527,88923,0,0,465,10187,0,0;QS=3,0;MQSB=0.547344;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,246:9:0 0,9,103:3:0 +17 2749 . C 0 . DP=26;I16=14,12,0,0,975,37353,0,0,1467,85323,0,0,463,10123,0,0;QS=3,0;MQSB=0.558035;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,232:9:0 0,9,98:3:0 +17 2750 . T 0 . DP=26;I16=15,11,0,0,982,37714,0,0,1498,88082,0,0,462,10086,0,0;QS=3,0;MQSB=0.738577;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,227:8:0 0,12,130:4:0 +17 2751 . G 0 . DP=26;I16=15,10,0,0,945,36031,0,0,1469,87241,0,0,437,9451,0,0;QS=3,0;MQSB=0.9171;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,205:8:0 0,9,103:3:0 +17 2752 . T 0 . DP=26;I16=15,11,0,0,870,30288,0,0,1498,88082,0,0,460,9998,0,0;QS=3,0;MQSB=0.738577;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,189:8:0 0,12,119:4:0 +17 2753 . G 0 . DP=26;I16=15,11,0,0,867,30913,0,0,1498,88082,0,0,458,9948,0,0;QS=3,0;MQSB=0.738577;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,202:8:0 0,12,116:4:0 +17 2754 . C 0 . DP=25;I16=14,10,0,0,873,32607,0,0,1409,83641,0,0,436,9484,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,205:8:0 0,9,104:3:0 +17 2755 . C 0 . DP=25;I16=14,10,0,0,865,32243,0,0,1409,83641,0,0,436,9528,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,209:8:0 0,9,97:3:0 +17 2756 . C 0 . DP=25;I16=14,9,0,0,838,31276,0,0,1380,82800,0,0,411,8971,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,204:8:0 0,9,97:3:0 +17 2757 . T 0 . DP=25;I16=14,11,0,0,904,33980,0,0,1438,84482,0,0,455,10011,0,0;QS=3,0;MQSB=0.745495;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,212:7:0 0,15,147:5:0 +17 2758 . T 0 . DP=25;I16=14,10,0,0,841,30293,0,0,1409,83641,0,0,439,9801,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,195:7:0 0,12,133:4:0 +17 2759 . A 0 . DP=25;I16=14,11,0,0,884,31728,0,0,1438,84482,0,0,457,10195,0,0;QS=3,0;MQSB=0.745495;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,192:7:0 0,15,147:5:0 +17 2760 . T 0 . DP=25;I16=14,11,0,0,907,33965,0,0,1438,84482,0,0,457,10275,0,0;QS=3,0;MQSB=0.745495;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,204:7:0 0,15,150:5:0 +17 2761 . T 0 . DP=23;I16=13,9,0,0,838,32530,0,0,1289,76441,0,0,444,10130,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,185:6:0 0,12,141:4:0 +17 2762 . T 0 . DP=24;I16=13,11,0,0,869,32261,0,0,1378,80882,0,0,459,10395,0,0;QS=3,0;MQSB=0.75304;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,178:6:0 0,18,177:6:0 +17 2763 . C A, 0 . DP=24;I16=13,10,0,1,843,31711,13,169,1349,80041,29,841,448,10290,12,144;QS=2.93333,0.0666667,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.75304;BQB=1;MQ0F=0 PL:DP:DV 0,36,255,36,255,255:12:0 0,18,170,18,170,170:6:0 0,5,147,15,150,153:6:1 +17 2764 . C 0 . DP=24;I16=13,10,0,0,854,32376,0,0,1349,80041,0,0,450,10374,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,163:6:0 0,15,162:5:0 +17 2765 . T 0 . DP=24;I16=12,11,0,0,853,32173,0,0,1318,77282,0,0,457,10469,0,0;QS=3,0;MQSB=0.7613;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,154:5:0 0,18,189:6:0 +17 2766 . C 0 . DP=24;I16=12,11,0,0,887,34485,0,0,1349,80041,0,0,448,10398,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,160:5:0 0,18,186:6:0 +17 2767 . T 0 . DP=24;I16=12,12,0,0,905,34757,0,0,1378,80882,0,0,458,10510,0,0;QS=3,0;MQSB=0.786628;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,153:5:0 0,21,217:7:0 +17 2768 . G 0 . DP=23;I16=11,11,0,0,852,33258,0,0,1289,76441,0,0,452,10462,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,141:5:0 0,18,197:6:0 +17 2769 . C 0 . DP=23;I16=11,12,0,0,832,31390,0,0,1318,77282,0,0,459,10481,0,0;QS=3,0;MQSB=0.795196;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,142:5:0 0,21,202:7:0 +17 2770 . T 0 . DP=23;I16=11,12,0,0,828,30854,0,0,1318,77282,0,0,459,10471,0,0;QS=3,0;MQSB=0.795196;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,152:5:0 0,21,199:7:0 +17 2771 . T 0 . DP=23;I16=11,11,0,0,817,30957,0,0,1258,73682,0,0,454,10456,0,0;QS=3,0;MQSB=0.770381;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,154:5:0 0,18,198:6:0 +17 2772 . T 0 . DP=23;I16=11,12,0,0,856,32206,0,0,1318,77282,0,0,459,10511,0,0;QS=3,0;MQSB=0.795196;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,160:5:0 0,21,210:7:0 +17 2773 . A 0 . DP=23;I16=11,12,0,0,828,30664,0,0,1318,77282,0,0,459,10561,0,0;QS=3,0;MQSB=0.795196;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,140:5:0 0,21,209:7:0 +17 2774 . G 0 . DP=22;I16=11,11,0,0,843,32715,0,0,1258,73682,0,0,458,10530,0,0;QS=3,0;MQSB=0.770381;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,154:5:0 0,21,207:7:0 +17 2775 . T 0 . DP=22;I16=10,11,0,0,748,27720,0,0,1198,70082,0,0,432,9892,0,0;QS=3,0;MQSB=0.780412;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,12,115:4:0 0,21,203:7:0 +17 2776 . G 0 . DP=22;I16=12,10,0,0,803,30251,0,0,1289,76441,0,0,456,10470,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,135:5:0 0,21,210:7:0 +17 2777 . A 0 . DP=22;I16=12,10,0,0,852,33524,0,0,1289,76441,0,0,456,10438,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,148:5:0 0,21,220:7:0 +17 2778 . G 0 . DP=23;I16=12,11,0,0,861,33049,0,0,1349,80041,0,0,456,10422,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,154:5:0 0,21,224:7:0 +17 2779 . G 0 . DP=23;I16=11,11,0,0,834,32014,0,0,1289,76441,0,0,432,9798,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,136:4:0 0,21,219:7:0 +17 2780 . A 0 . DP=23;I16=11,11,0,0,792,29162,0,0,1289,76441,0,0,433,9817,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,33,244:11:0 0,12,133:4:0 0,21,215:7:0 +17 2781 . A 0 . DP=23;I16=11,11,0,0,844,33092,0,0,1289,76441,0,0,441,10141,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,15,151:5:0 0,21,233:7:0 +17 2782 . G 0 . DP=23;I16=12,11,0,0,840,31826,0,0,1349,80041,0,0,458,10438,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,154:5:0 0,21,218:7:0 +17 2783 . A 0 . DP=23;I16=11,11,0,0,860,33888,0,0,1289,76441,0,0,432,9790,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,142:4:0 0,21,230:7:0 +17 2784 . G 0 . DP=23;I16=12,11,0,0,860,33092,0,0,1349,80041,0,0,456,10410,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,143:5:0 0,21,212:7:0 +17 2785 . G 0 . DP=23;I16=11,11,0,0,797,29747,0,0,1289,76441,0,0,429,9749,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,134:4:0 0,21,204:7:0 +17 2786 . C 0 . DP=24;I16=12,12,0,0,831,29497,0,0,1409,83641,0,0,451,10309,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,141:5:0 0,21,199:7:0 +17 2787 . C 0 . DP=24;I16=11,12,0,0,792,28454,0,0,1349,80041,0,0,424,9642,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,36,252:12:0 0,12,127:4:0 0,21,200:7:0 +17 2788 . C 0 . DP=23;I16=11,11,0,0,791,29517,0,0,1289,76441,0,0,421,9523,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,125:4:0 0,21,209:7:0 +17 2789 . C 0 . DP=24;I16=13,11,0,0,880,33470,0,0,1409,83641,0,0,443,10051,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,150:5:0 0,21,226:7:0 +17 2790 . T 0 . DP=23;I16=13,10,0,0,886,34738,0,0,1349,80041,0,0,442,9976,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,165:5:0 0,21,227:7:0 +17 2791 . G 0 . DP=23;I16=13,10,0,0,873,34037,0,0,1349,80041,0,0,441,9923,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,155:5:0 0,21,226:7:0 +17 2792 . G 0 . DP=23;I16=13,10,0,0,832,30870,0,0,1349,80041,0,0,438,9792,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,15,146:5:0 0,21,221:7:0 +17 2793 . T 0 . DP=23;I16=13,10,0,0,827,30693,0,0,1349,80041,0,0,435,9683,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,33,247:11:0 0,15,157:5:0 0,21,214:7:0 +17 2794 . C 0 . DP=22;I16=12,10,0,0,786,29122,0,0,1289,76441,0,0,433,9595,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,145:5:0 0,21,201:7:0 +17 2795 . C 0 . DP=22;I16=11,10,0,0,814,31804,0,0,1229,72841,0,0,428,9518,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,15,159:5:0 0,21,222:7:0 +17 2796 . A 0 . DP=22;I16=11,10,0,0,762,28412,0,0,1229,72841,0,0,427,9475,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,27,221:9:0 0,15,156:5:0 0,21,211:7:0 +17 2797 . T 0 . DP=22;I16=12,10,0,0,792,29116,0,0,1289,76441,0,0,427,9451,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,15,148:5:0 0,21,214:7:0 +17 2798 . G 0 . DP=22;I16=12,10,0,0,817,31105,0,0,1289,76441,0,0,424,9394,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,152:5:0 0,21,205:7:0 +17 2799 . A 0 . DP=21;I16=11,10,0,0,788,30210,0,0,1229,72841,0,0,421,9309,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,27,220:9:0 0,15,167:5:0 0,21,218:7:0 +17 2800 . A 0 . DP=21;I16=11,10,0,0,836,33616,0,0,1229,72841,0,0,418,9246,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,27,237:9:0 0,15,164:5:0 0,21,237:7:0 +17 2801 . G 0 . DP=21;I16=11,10,0,0,792,30182,0,0,1229,72841,0,0,415,9205,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,27,234:9:0 0,15,157:5:0 0,21,214:7:0 +17 2802 . G 0 . DP=21;I16=11,9,0,0,729,27275,0,0,1169,69241,0,0,387,8559,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,24,229:8:0 0,15,135:5:0 0,21,215:7:0 +17 2803 . G 0 . DP=21;I16=11,10,0,0,737,26709,0,0,1229,72841,0,0,406,9036,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,15,125:5:0 0,21,207:7:0 +17 2804 . G 0 . DP=21;I16=11,10,0,0,727,26103,0,0,1229,72841,0,0,400,8908,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,27,218:9:0 0,15,129:5:0 0,21,210:7:0 +17 2805 . C 0 . DP=21;I16=10,10,0,0,714,26194,0,0,1169,69241,0,0,372,8316,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,27,229:9:0 0,12,111:4:0 0,21,205:7:0 +17 2806 . C 0 . DP=20;I16=11,8,0,0,682,25074,0,0,1109,65641,0,0,379,8611,0,0;QS=3,0;MQSB=0.902014;MQ0F=0 PL:DP:DV 0,24,215:8:0 0,15,138:5:0 0,18,191:6:0 +17 2807 . T 0 . DP=20;I16=11,9,0,0,755,29373,0,0,1169,69241,0,0,384,8640,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,15,152:5:0 0,21,227:7:0 +17 2808 . T 0 . DP=20;I16=11,9,0,0,749,28383,0,0,1169,69241,0,0,379,8587,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,24,209:8:0 0,15,157:5:0 0,21,225:7:0 +17 2809 . T 0 . DP=20;I16=11,8,0,0,697,26019,0,0,1109,65641,0,0,349,7927,0,0;QS=3,0;MQSB=0.902014;MQ0F=0 PL:DP:DV 0,21,189:7:0 0,15,148:5:0 0,21,226:7:0 +17 2810 . C 0 . DP=20;I16=12,8,0,0,754,28900,0,0,1169,69241,0,0,368,8436,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,24,229:8:0 0,15,150:5:0 0,21,215:7:0 +17 2811 . A 0 . DP=19;I16=11,8,0,0,759,30405,0,0,1109,65641,0,0,364,8340,0,0;QS=3,0;MQSB=0.902014;MQ0F=0 PL:DP:DV 0,21,209:7:0 0,15,166:5:0 0,21,228:7:0 +17 2812 . G 0 . DP=20;I16=11,9,0,0,758,29062,0,0,1169,69241,0,0,359,8213,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,24,229:8:0 0,15,150:5:0 0,21,216:7:0 +17 2813 . A 0 . DP=19;I16=11,8,0,0,702,27106,0,0,1140,68400,0,0,356,8104,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,195:7:0 0,15,160:5:0 0,21,217:7:0 +17 2814 . G 0 . DP=19;I16=11,8,0,0,703,26579,0,0,1140,68400,0,0,353,8013,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,217:7:0 0,15,147:5:0 0,21,204:7:0 +17 2815 . A 0 . DP=19;I16=10,7,0,0,597,21979,0,0,1020,61200,0,0,326,7470,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,170:6:0 0,12,122:4:0 0,21,208:7:0 +17 2816 . C 0 . DP=19;I16=11,8,0,0,630,21880,0,0,1140,68400,0,0,343,7685,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,193:7:0 0,15,134:5:0 0,21,180:7:0 +17 2817 . G 0 . DP=20;I16=11,8,0,0,612,20368,0,0,1140,68400,0,0,339,7547,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,200:7:0 0,15,115:5:0 0,21,178:7:0 +17 2818 . G 0 . DP=20;I16=11,8,0,0,688,25280,0,0,1140,68400,0,0,335,7377,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,216:7:0 0,15,132:5:0 0,21,206:7:0 +17 2819 . G 0 . DP=20;I16=11,8,0,0,696,25880,0,0,1140,68400,0,0,331,7227,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,222:7:0 0,15,142:5:0 0,21,195:7:0 +17 2820 . G 0 . DP=20;I16=10,8,0,0,624,22228,0,0,1080,64800,0,0,320,7048,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,205:7:0 0,12,119:4:0 0,21,188:7:0 +17 2821 . A 0 . DP=20;I16=9,7,0,0,496,16222,0,0,960,57600,0,0,279,6157,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,159:6:0 0,9,93:3:0 0,21,171:7:0 +17 2822 . C 0 . DP=19;I16=8,9,0,0,543,18163,0,0,1020,61200,0,0,310,7064,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,203:7:0 0,9,79:3:0 0,21,168:7:0 +17 2823 . C 0 . DP=18;I16=9,7,0,0,550,19506,0,0,960,57600,0,0,300,6640,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,201:7:0 0,6,58:2:0 0,21,192:7:0 +17 2824 . C 0 . DP=18;I16=9,7,0,0,584,21560,0,0,960,57600,0,0,299,6567,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,219:8:0 0,3,37:1:0 0,21,210:7:0 +17 2825 . C 0 . DP=18;I16=9,8,0,0,606,22286,0,0,1020,61200,0,0,324,7134,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,234:8:0 0,3,37:1:0 0,24,208:8:0 +17 2826 . T 0 . DP=18;I16=9,8,0,0,604,21766,0,0,1020,61200,0,0,323,7043,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,222:8:0 0,3,33:1:0 0,24,220:8:0 +17 2827 . G 0 . DP=18;I16=9,8,0,0,597,21643,0,0,1020,61200,0,0,322,6970,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,230:8:0 0,3,28:1:0 0,24,214:8:0 +17 2828 . A 0 . DP=20;I16=9,9,0,0,598,20740,0,0,1080,64800,0,0,321,6915,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,213:9:0 0,3,36:1:0 0,24,219:8:0 +17 2829 . G 0 . DP=20;I16=9,9,0,0,649,23719,0,0,1080,64800,0,0,305,6591,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,239:8:0 0,3,31:1:0 0,27,227:9:0 +17 2830 . G 0 . DP=20;I16=9,10,0,0,661,23841,0,0,1140,68400,0,0,323,6867,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,248:9:0 0,3,34:1:0 0,27,222:9:0 +17 2831 . A 0 . DP=21;I16=10,10,0,0,682,24052,0,0,1200,72000,0,0,324,6876,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,223:9:0 0,3,34:1:0 0,30,254:10:0 +17 2832 . G 0 . DP=21;I16=10,8,0,0,626,22384,0,0,1080,64800,0,0,281,5883,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,230:8:0 0,3,31:1:0 0,27,223:9:0 +17 2833 . C 0 . DP=21;I16=10,10,0,0,712,25708,0,0,1200,72000,0,0,327,6915,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,3,37:1:0 0,30,255:10:0 +17 2834 . C 0 . DP=21;I16=10,9,0,0,674,24470,0,0,1140,68400,0,0,306,6464,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,230:8:0 0,3,36:1:0 0,30,243:10:0 +17 2835 . C 0 . DP=20;I16=9,9,0,0,617,21835,0,0,1080,64800,0,0,305,6381,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,202:8:0 0,3,39:1:0 0,27,235:9:0 +17 2836 . C 0 . DP=20;I16=9,9,0,0,580,19624,0,0,1080,64800,0,0,306,6412,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,206:8:0 0,3,39:1:0 0,27,200:9:0 +17 2837 . G 0 . DP=21;I16=9,10,0,0,558,17614,0,0,1140,68400,0,0,330,7086,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,207:9:0 0,3,31:1:0 0,27,193:9:0 +17 2838 . A 0 . DP=20;I16=9,10,0,0,640,22674,0,0,1140,68400,0,0,331,7065,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,245:9:0 0,3,17:1:0 0,27,220:9:0 +17 2839 . G 0 . DP=20;I16=9,8,0,0,623,23267,0,0,1020,61200,0,0,282,5816,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,248:8:0 0,3,26:1:0 0,24,212:8:0 +17 2840 . C 0 . DP=20;I16=9,10,0,0,644,22798,0,0,1140,68400,0,0,333,7089,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,3,32:1:0 0,27,227:9:0 +17 2841 . A 0 . DP=20;I16=9,9,0,0,675,25801,0,0,1080,64800,0,0,309,6509,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,252:9:0 0,3,35:1:0 0,24,234:8:0 +17 2842 . G 0 . DP=20;I16=9,10,0,0,688,25554,0,0,1140,68400,0,0,332,7056,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,3,31:1:0 0,27,233:9:0 +17 2843 . C 0 . DP=20;I16=8,10,0,0,651,23969,0,0,1080,64800,0,0,309,6517,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,0,0:0:0 0,24,211:8:0 +17 2844 . A 0 . DP=20;I16=8,11,0,0,685,25399,0,0,1140,68400,0,0,331,6969,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,0,0:0:0 0,27,231:9:0 +17 2845 . G 0 . DP=20;I16=8,10,0,0,673,25399,0,0,1080,64800,0,0,311,6561,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,0,0:0:0 0,24,228:8:0 +17 2846 . C 0 . DP=20;I16=8,10,0,0,617,22007,0,0,1080,64800,0,0,311,6577,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,0,0:0:0 0,24,218:8:0 +17 2847 . C 0 . DP=20;I16=7,11,0,0,580,19468,0,0,1080,64800,0,0,321,6917,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,241:10:0 0,0,0:0:0 0,24,187:8:0 +17 2848 . G 0 . DP=19;I16=7,10,0,0,542,17884,0,0,1020,61200,0,0,323,6999,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,218:9:0 0,0,0:0:0 0,24,191:8:0 +17 2849 . T 0 . DP=19;I16=7,11,0,0,609,21717,0,0,1080,64800,0,0,341,7357,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,231:9:0 0,0,0:0:0 0,27,214:9:0 +17 2850 . C 0 . DP=19;I16=7,11,0,0,574,18980,0,0,1080,64800,0,0,343,7461,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,234:9:0 0,0,0:0:0 0,27,188:9:0 +17 2851 . G 0 . DP=17;I16=6,11,0,0,589,20831,0,0,1020,61200,0,0,346,7584,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,0,0:0:0 0,24,194:8:0 +17 2852 . T 0 . DP=17;I16=6,11,0,0,625,23241,0,0,1020,61200,0,0,348,7676,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,0,0:0:0 0,24,214:8:0 +17 2853 . G 0 . DP=17;I16=6,11,0,0,635,23949,0,0,1020,61200,0,0,349,7739,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,0,0:0:0 0,24,202:8:0 +17 2854 . T 0 . DP=17;I16=6,11,0,0,602,21990,0,0,1020,61200,0,0,348,7722,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,0,0:0:0 0,24,207:8:0 +17 2855 . C 0 . DP=17;I16=6,10,0,0,577,21539,0,0,960,57600,0,0,337,7623,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,0,0:0:0 0,21,185:7:0 +17 2856 . T 0 . DP=17;I16=6,8,0,0,530,20570,0,0,840,50400,0,0,289,6507,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,252:9:0 0,0,0:0:0 0,15,167:5:0 +17 2857 . C 0 . DP=18;I16=6,10,0,0,577,21641,0,0,960,57600,0,0,336,7664,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,0,0:0:0 0,21,185:7:0 +17 2858 . A 0 . DP=19;I16=6,12,0,0,634,23006,0,0,1080,64800,0,0,355,8081,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,254:10:0 0,3,39:1:0 0,21,185:7:0 +17 2859 . C 0 . DP=19;I16=6,13,0,0,646,23056,0,0,1140,68400,0,0,361,8139,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,3,26:1:0 0,24,194:8:0 +17 2860 . C 0 . DP=19;I16=6,13,0,0,655,23687,0,0,1140,68400,0,0,360,8166,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,251:10:0 0,3,37:1:0 0,24,200:8:0 +17 2861 . C 0 . DP=20;I16=7,12,0,0,708,26756,0,0,1140,68400,0,0,333,7537,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,38:1:0 0,21,203:7:0 +17 2862 . A 0 . DP=20;I16=6,13,0,0,749,29753,0,0,1140,68400,0,0,332,7554,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,3,43:1:0 0,24,225:8:0 +17 2863 . G 0 . DP=19;I16=7,12,0,0,707,26901,0,0,1140,68400,0,0,356,8166,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,35:1:0 0,21,195:7:0 +17 2864 . G 0 . DP=19;I16=7,11,0,0,677,25833,0,0,1080,64800,0,0,352,8070,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,36:1:0 0,18,185:6:0 +17 2865 . G 0 . DP=19;I16=7,12,0,0,671,24569,0,0,1140,68400,0,0,350,7994,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,27:1:0 0,21,193:7:0 +17 2866 . T 0 . DP=18;I16=6,11,0,0,591,21071,0,0,1020,61200,0,0,338,7834,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,32:1:0 0,15,147:5:0 +17 2867 . G 0 . DP=18;I16=7,11,0,0,655,24279,0,0,1080,64800,0,0,347,7889,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,58:2:0 0,15,150:5:0 +17 2868 . T 0 . DP=18;I16=7,11,0,0,640,23702,0,0,1080,64800,0,0,347,7859,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,68:2:0 0,15,157:5:0 +17 2869 . C 0 . DP=18;I16=7,11,0,0,655,24737,0,0,1080,64800,0,0,346,7794,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,56:2:0 0,15,165:5:0 +17 2870 . T 0 . DP=18;I16=7,11,0,0,700,27480,0,0,1080,64800,0,0,345,7743,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,70:2:0 0,15,176:5:0 +17 2871 . G 0 . DP=18;I16=7,11,0,0,700,27554,0,0,1080,64800,0,0,344,7706,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,68:2:0 0,15,172:5:0 +17 2872 . A 0 . DP=18;I16=7,11,0,0,651,23869,0,0,1080,64800,0,0,343,7683,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,66:2:0 0,15,171:5:0 +17 2873 . A 0 . DP=18;I16=7,11,0,0,664,25000,0,0,1080,64800,0,0,342,7674,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,61:2:0 0,15,159:5:0 +17 2874 . A 0 . DP=18;I16=7,11,0,0,636,23286,0,0,1080,64800,0,0,341,7679,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,57:2:0 0,15,162:5:0 +17 2875 . C 0 . DP=18;I16=7,11,0,0,664,25148,0,0,1080,64800,0,0,340,7698,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,63:2:0 0,15,166:5:0 +17 2876 . A 0 . DP=18;I16=6,11,0,0,666,26684,0,0,1020,61200,0,0,314,7106,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,6,74:2:0 0,15,185:5:0 +17 2877 . G 0 . DP=17;I16=6,11,0,0,659,26009,0,0,1020,61200,0,0,339,7777,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,67:2:0 0,12,148:4:0 +17 2878 . A 0 . DP=17;I16=7,10,0,0,628,23656,0,0,1020,61200,0,0,340,7834,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,6,69:2:0 0,15,166:5:0 +17 2879 . T 0 . DP=18;I16=7,11,0,0,671,25359,0,0,1080,64800,0,0,342,7902,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,9,96:3:0 0,15,175:5:0 +17 2880 . G 0 . DP=19;I16=8,11,0,0,708,26694,0,0,1140,68400,0,0,345,7983,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,118:4:0 0,15,173:5:0 +17 2881 . T 0 . DP=19;I16=6,11,0,0,618,23304,0,0,1020,61200,0,0,299,6829,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,209:8:0 0,12,124:4:0 0,15,178:5:0 +17 2882 . G 0 . DP=19;I16=8,11,0,0,700,26464,0,0,1140,68400,0,0,353,8191,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,118:4:0 0,15,176:5:0 +17 2883 . G 0 . DP=19;I16=8,11,0,0,707,26939,0,0,1140,68400,0,0,357,8319,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,121:4:0 0,15,175:5:0 +17 2884 . A 0 . DP=19;I16=7,11,0,0,649,24531,0,0,1080,64800,0,0,335,7787,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,229:9:0 0,12,121:4:0 0,15,181:5:0 +17 2885 . G 0 . DP=19;I16=8,11,0,0,737,29253,0,0,1140,68400,0,0,362,8470,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,113:4:0 0,15,182:5:0 +17 2886 . G A, 0 . DP=18;I16=7,9,1,0,571,21281,20,400,960,57600,60,3600,334,7882,6,36;QS=2.76471,0.235294,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,27,236,27,236,236:9:0 11,0,51,17,54,66:3:1 0,15,171,15,171,171:5:0 +17 2887 . T 0 . DP=19;I16=9,9,0,0,581,20407,0,0,1080,64800,0,0,341,7905,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,213:10:0 0,9,94:3:0 0,15,166:5:0 +17 2888 . C 0 . DP=20;I16=10,10,0,0,714,26630,0,0,1200,72000,0,0,368,8532,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,94:4:0 0,15,159:5:0 +17 2889 . T 0 . DP=19;I16=9,10,0,0,712,27106,0,0,1140,68400,0,0,372,8550,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,114:4:0 0,15,175:5:0 +17 2890 . C 0 . DP=19;I16=9,10,0,0,613,20711,0,0,1140,68400,0,0,376,8584,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,12,95:4:0 0,15,139:5:0 +17 2891 . G 0 . DP=20;I16=9,11,0,0,674,23754,0,0,1200,72000,0,0,380,8634,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,242:10:0 0,15,141:5:0 0,15,143:5:0 +17 2892 . G 0 . DP=21;I16=9,12,0,0,731,26677,0,0,1260,75600,0,0,385,8701,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,142:5:0 0,15,164:5:0 +17 2893 . G 0 . DP=21;I16=9,12,0,0,696,24498,0,0,1260,75600,0,0,389,8687,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,251:11:0 0,15,141:5:0 0,15,150:5:0 +17 2894 . T 0 . DP=21;I16=9,12,0,0,716,25490,0,0,1260,75600,0,0,393,8693,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,137:5:0 0,15,155:5:0 +17 2895 . G 0 . DP=22;I16=9,12,0,0,773,29225,0,0,1260,75600,0,0,372,8094,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,149:6:0 0,15,166:5:0 +17 2896 . A 0 . DP=22;I16=8,12,0,0,732,27684,0,0,1200,72000,0,0,361,7885,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,151:5:0 0,15,163:5:0 +17 2897 . G 0 . DP=22;I16=10,12,0,0,783,28783,0,0,1320,79200,0,0,407,8835,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,161:6:0 0,15,168:5:0 +17 2898 . G 0 . DP=22;I16=10,12,0,0,724,25596,0,0,1320,79200,0,0,412,8926,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,18,143:6:0 0,15,169:5:0 +17 2899 . C 0 . DP=22;I16=8,11,0,0,625,21143,0,0,1140,68400,0,0,356,7640,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,15,130:5:0 0,15,147:5:0 +17 2900 . G 0 . DP=24;I16=11,13,0,0,782,26700,0,0,1440,86400,0,0,420,9078,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,164:6:0 0,15,153:5:0 +17 2901 . T 0 . DP=24;I16=11,13,0,0,821,29195,0,0,1440,86400,0,0,426,9192,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,174:6:0 0,15,166:5:0 +17 2902 . G 0 . DP=24;I16=11,13,0,0,898,34176,0,0,1440,86400,0,0,432,9334,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,171:6:0 0,15,164:5:0 +17 2903 . G 0 . DP=24;I16=11,13,0,0,894,33764,0,0,1440,86400,0,0,437,9455,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,183:6:0 0,15,168:5:0 +17 2904 . C 0 . DP=24;I16=11,13,0,0,892,34010,0,0,1440,86400,0,0,440,9506,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,176:6:0 0,15,169:5:0 +17 2905 . T 0 . DP=25;I16=12,13,0,0,926,34994,0,0,1500,90000,0,0,442,9536,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,175:6:0 0,15,174:5:0 +17 2906 . C 0 . DP=25;I16=12,13,0,0,960,37070,0,0,1500,90000,0,0,444,9544,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,178:6:0 0,15,173:5:0 +17 2907 . A 0 . DP=25;I16=11,13,0,0,933,36707,0,0,1440,86400,0,0,429,9275,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,202:6:0 0,15,170:5:0 +17 2908 . G 0 . DP=25;I16=12,13,0,0,943,36315,0,0,1500,90000,0,0,446,9548,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,167:6:0 0,15,164:5:0 +17 2909 . A 0 . DP=25;I16=10,13,0,0,864,32764,0,0,1380,82800,0,0,425,9105,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,182:6:0 0,15,171:5:0 +17 2910 . T 0 . DP=25;I16=11,13,0,0,870,32054,0,0,1440,86400,0,0,447,9575,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,181:6:0 0,15,166:5:0 +17 2911 . A 0 . DP=25;I16=11,14,0,0,871,31227,0,0,1500,90000,0,0,473,10259,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,174:6:0 0,18,188:6:0 +17 2912 . C 0 . DP=24;I16=11,13,0,0,899,34121,0,0,1440,86400,0,0,474,10298,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,173:6:0 0,18,189:6:0 +17 2913 . A 0 . DP=24;I16=10,13,0,0,879,34357,0,0,1380,82800,0,0,449,9691,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,164:5:0 0,18,199:6:0 +17 2914 . G 0 . DP=24;I16=11,13,0,0,899,34575,0,0,1440,86400,0,0,472,10262,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,170:6:0 0,18,187:6:0 +17 2915 . G 0 . DP=24;I16=11,13,0,0,867,32523,0,0,1440,86400,0,0,470,10236,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,177:6:0 0,18,178:6:0 +17 2916 . G 0 . DP=24;I16=11,12,0,0,813,29935,0,0,1380,82800,0,0,443,9613,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,173:6:0 0,15,155:5:0 +17 2917 . A 0 . DP=25;I16=11,13,0,0,864,31926,0,0,1440,86400,0,0,459,10181,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,185:6:0 0,18,178:6:0 +17 2918 . G 0 . DP=25;I16=13,12,0,0,903,33489,0,0,1500,90000,0,0,462,10122,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,165:6:0 0,18,170:6:0 +17 2919 . T 0 . DP=25;I16=12,12,0,0,837,29647,0,0,1440,86400,0,0,443,9765,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,169:6:0 0,18,178:6:0 +17 2920 . G 0 . DP=25;I16=12,12,0,0,850,31266,0,0,1440,86400,0,0,433,9389,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,132:5:0 0,18,180:6:0 +17 2921 . G 0 . DP=25;I16=13,12,0,0,874,31518,0,0,1500,90000,0,0,455,9951,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,159:6:0 0,18,176:6:0 +17 2922 . C 0 . DP=26;I16=13,12,0,0,872,31374,0,0,1500,90000,0,0,438,9718,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,160:6:0 0,18,172:6:0 +17 2923 . C 0 . DP=26;I16=13,12,0,0,873,31687,0,0,1500,90000,0,0,437,9735,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,172:6:0 0,18,175:6:0 +17 2924 . C 0 . DP=25;I16=13,12,0,0,940,36016,0,0,1500,90000,0,0,449,9921,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,173:6:0 0,18,184:6:0 +17 2925 . A 0 . DP=25;I16=13,12,0,0,912,33580,0,0,1500,90000,0,0,448,9964,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,174:6:0 0,18,189:6:0 +17 2926 . C 0 . DP=25;I16=13,12,0,0,902,33224,0,0,1500,90000,0,0,445,9931,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,176:6:0 0,18,174:6:0 +17 2927 . A 0 . DP=25;I16=12,12,0,0,896,33828,0,0,1440,86400,0,0,417,9295,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,162:5:0 0,18,191:6:0 +17 2928 . G 0 . DP=24;I16=13,11,0,0,862,32078,0,0,1440,86400,0,0,440,9930,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,170:6:0 0,18,161:6:0 +17 2929 . C 0 . DP=23;I16=13,9,0,0,794,29716,0,0,1320,79200,0,0,430,9878,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,153:5:0 0,15,149:5:0 +17 2930 . T 0 . DP=23;I16=13,10,0,0,822,30260,0,0,1380,82800,0,0,438,10006,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,168:6:0 0,15,157:5:0 +17 2931 . C 0 . DP=23;I16=13,10,0,0,803,28963,0,0,1380,82800,0,0,436,10020,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,162:6:0 0,15,140:5:0 +17 2932 . G 0 . DP=22;I16=12,10,0,0,728,25158,0,0,1320,79200,0,0,435,10049,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,171:6:0 0,12,117:4:0 +17 2933 . G 0 . DP=22;I16=11,10,0,0,760,28336,0,0,1260,75600,0,0,430,10034,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,175:6:0 0,12,116:4:0 +17 2934 . C 0 . DP=21;I16=12,9,0,0,759,28241,0,0,1260,75600,0,0,432,10052,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,161:6:0 0,9,104:3:0 +17 2935 . C 0 . DP=21;I16=12,9,0,0,766,28494,0,0,1260,75600,0,0,431,10075,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,178:6:0 0,9,94:3:0 +17 2936 . T 0 . DP=21;I16=11,9,0,0,760,29284,0,0,1200,72000,0,0,429,10063,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,188:6:0 0,9,98:3:0 +17 2937 . G 0 . DP=20;I16=11,9,0,0,728,27374,0,0,1200,72000,0,0,428,10066,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,177:6:0 0,9,79:3:0 +17 2938 . T 0 . DP=20;I16=11,9,0,0,719,26217,0,0,1200,72000,0,0,427,10083,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,188:6:0 0,9,101:3:0 +17 2939 . C 0 . DP=19;I16=11,8,0,0,729,28277,0,0,1140,68400,0,0,427,10113,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,163:5:0 0,9,106:3:0 +17 2940 . T 0 . DP=19;I16=11,8,0,0,739,29133,0,0,1140,68400,0,0,427,10155,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,171:5:0 0,9,109:3:0 +17 2941 . T 0 . DP=19;I16=11,8,0,0,702,26358,0,0,1140,68400,0,0,427,10209,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,170:5:0 0,9,99:3:0 +17 2942 . T 0 . DP=19;I16=11,8,0,0,695,25671,0,0,1140,68400,0,0,427,10275,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,169:5:0 0,9,100:3:0 +17 2943 . G 0 . DP=18;I16=11,6,0,0,621,23187,0,0,1020,61200,0,0,401,9627,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,15,170:5:0 0,9,86:3:0 +17 2944 . A 0 . DP=18;I16=10,7,0,0,642,24406,0,0,1020,61200,0,0,399,9563,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,15,168:5:0 0,9,111:3:0 +17 2945 . A 0 . DP=18;I16=11,7,0,0,637,23199,0,0,1080,64800,0,0,422,10132,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,242:10:0 0,15,152:5:0 0,9,107:3:0 +17 2946 . A 0 . DP=18;I16=11,7,0,0,692,26794,0,0,1080,64800,0,0,420,10084,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,174:5:0 0,9,108:3:0 +17 2947 . G 0 . DP=18;I16=11,7,0,0,639,23329,0,0,1080,64800,0,0,418,10044,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,160:5:0 0,9,78:3:0 +17 2948 . G 0 . DP=19;I16=11,8,0,0,702,26272,0,0,1140,68400,0,0,415,9961,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,163:5:0 0,12,116:4:0 +17 2949 . C 0 . DP=19;I16=10,8,0,0,657,24565,0,0,1080,64800,0,0,388,9260,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,125:4:0 0,12,124:4:0 +17 2950 . C 0 . DP=19;I16=11,8,0,0,667,24359,0,0,1140,68400,0,0,411,9817,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,131:5:0 0,12,115:4:0 +17 2951 . A 0 . DP=20;I16=11,8,0,0,682,24956,0,0,1140,68400,0,0,409,9757,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,15,149:5:0 0,12,133:4:0 +17 2952 . C 0 . DP=20;I16=11,9,0,0,647,21709,0,0,1200,72000,0,0,408,9706,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,128:5:0 0,12,112:4:0 +17 2953 . G 0 . DP=21;I16=11,9,0,0,620,19954,0,0,1200,72000,0,0,407,9665,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,237:11:0 0,15,132:5:0 0,12,111:4:0 +17 2954 . T 0 . DP=21;I16=11,10,0,0,742,26662,0,0,1260,75600,0,0,414,9666,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,175:6:0 0,12,135:4:0 +17 2955 . G 0 . DP=22;I16=11,11,0,0,787,28475,0,0,1320,79200,0,0,412,9568,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,170:6:0 0,12,127:4:0 +17 2956 . A 0 . DP=22;I16=11,11,0,0,747,26449,0,0,1320,79200,0,0,410,9438,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,161:6:0 0,12,125:4:0 +17 2957 . C 0 . DP=22;I16=10,10,0,0,693,24757,0,0,1200,72000,0,0,358,8078,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,143:6:0 0,9,104:3:0 +17 2958 . C 0 . DP=21;I16=11,10,0,0,784,29744,0,0,1260,75600,0,0,407,9237,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,172:6:0 0,12,135:4:0 +17 2959 . T 0 . DP=21;I16=11,10,0,0,791,30411,0,0,1260,75600,0,0,406,9164,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,182:6:0 0,12,139:4:0 +17 2960 . G 0 . DP=21;I16=11,10,0,0,778,29502,0,0,1260,75600,0,0,405,9109,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,178:6:0 0,12,126:4:0 +17 2961 . G 0 . DP=20;I16=10,9,0,0,657,23303,0,0,1140,68400,0,0,380,8446,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,231:10:0 0,18,176:6:0 0,9,111:3:0 +17 2962 . C 0 . DP=21;I16=10,10,0,0,731,27459,0,0,1200,72000,0,0,385,8615,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,151:5:0 0,12,132:4:0 +17 2963 . C 0 . DP=21;I16=10,10,0,0,722,26502,0,0,1200,72000,0,0,378,8274,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,169:6:0 0,9,100:3:0 +17 2964 . C 0 . DP=22;I16=11,10,0,0,752,27740,0,0,1260,75600,0,0,379,8275,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,148:5:0 0,15,151:5:0 +17 2965 . A 0 . DP=22;I16=11,11,0,0,804,29606,0,0,1320,79200,0,0,397,8539,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,176:6:0 0,15,155:5:0 +17 2966 . C 0 . DP=22;I16=11,11,0,0,705,23557,0,0,1320,79200,0,0,396,8468,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,18,146:6:0 0,15,142:5:0 +17 2967 . G 0 . DP=24;I16=11,13,0,0,767,25405,0,0,1440,86400,0,0,393,8325,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,162:6:0 0,18,135:6:0 +17 2968 . G 0 . DP=23;I16=11,12,0,0,812,29824,0,0,1380,82800,0,0,393,8213,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,152:5:0 0,18,162:6:0 +17 2969 . C 0 . DP=23;I16=11,12,0,0,866,32982,0,0,1380,82800,0,0,393,8133,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,151:5:0 0,18,181:6:0 +17 2970 . T 0 . DP=24;I16=11,12,0,0,816,29806,0,0,1380,82800,0,0,393,8085,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,154:5:0 0,18,189:6:0 +17 2971 . G 0 . DP=24;I16=12,12,0,0,878,33010,0,0,1440,86400,0,0,392,7970,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,173:6:0 0,18,184:6:0 +17 2972 . G 0 . DP=24;I16=12,12,0,0,839,30363,0,0,1440,86400,0,0,391,7889,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,175:6:0 0,18,161:6:0 +17 2973 . C 0 . DP=24;I16=12,12,0,0,854,31154,0,0,1440,86400,0,0,390,7842,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,177:6:0 0,18,165:6:0 +17 2974 . A 0 . DP=24;I16=12,12,0,0,869,32231,0,0,1440,86400,0,0,388,7778,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,169:6:0 0,18,174:6:0 +17 2975 . G 0 . DP=24;I16=12,12,0,0,857,31835,0,0,1440,86400,0,0,384,7648,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,173:6:0 0,18,167:6:0 +17 2976 . G 0 . DP=25;I16=13,12,0,0,866,31118,0,0,1500,90000,0,0,380,7554,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,180:7:0 0,18,171:6:0 +17 2977 . T 0 . DP=26;I16=13,12,0,0,760,25216,0,0,1469,87241,0,0,373,7437,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,151:6:0 0,18,155:6:0 +17 2978 . G 0 . DP=25;I16=12,12,0,0,862,31574,0,0,1409,83641,0,0,362,7290,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,168:6:0 0,18,167:6:0 +17 2979 . G 0 . DP=24;I16=12,12,0,0,816,28440,0,0,1409,83641,0,0,370,7340,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,164:6:0 0,15,142:5:0 +17 2980 . G 0 . DP=23;I16=12,11,0,0,834,30882,0,0,1349,80041,0,0,369,7293,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,144:5:0 0,15,148:5:0 +17 2981 . A 0 . DP=23;I16=9,11,0,0,622,20306,0,0,1169,69241,0,0,318,6244,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,30,201:10:0 0,15,145:5:0 0,15,150:5:0 +17 2982 . C 0 . DP=23;I16=10,11,0,0,706,24366,0,0,1229,72841,0,0,340,6884,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,93:3:0 0,15,144:5:0 +17 2983 . C 0 . DP=23;I16=12,11,0,0,781,27427,0,0,1349,80041,0,0,363,7197,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,137:5:0 0,15,142:5:0 +17 2984 . C 0 . DP=23;I16=12,11,0,0,861,32655,0,0,1349,80041,0,0,361,7229,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,154:5:0 0,15,157:5:0 +17 2985 . A 0 . DP=23;I16=12,11,0,0,798,28906,0,0,1349,80041,0,0,359,7293,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,161:5:0 0,15,151:5:0 +17 2986 . G 0 . DP=21;I16=11,10,0,0,701,24335,0,0,1229,72841,0,0,358,7388,0,0;QS=3,0;MQSB=0.939898;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,129:5:0 0,12,126:4:0 +17 2987 . C 0 . DP=21;I16=10,10,0,0,720,26782,0,0,1169,69241,0,0,350,7448,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,136:4:0 0,12,132:4:0 +17 2988 . T 0 . DP=20;I16=10,10,0,0,693,25143,0,0,1169,69241,0,0,358,7612,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,132:5:0 0,12,136:4:0 +17 2989 . G 0 . DP=20;I16=10,10,0,0,708,25886,0,0,1169,69241,0,0,358,7736,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,141:5:0 0,12,125:4:0 +17 2990 . C 0 . DP=20;I16=10,10,0,0,697,25083,0,0,1169,69241,0,0,357,7833,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,149:5:0 0,12,129:4:0 +17 2991 . A 0 . DP=20;I16=10,10,0,0,717,26309,0,0,1169,69241,0,0,356,7952,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,151:5:0 0,12,131:4:0 +17 2992 . G 0 . DP=18;I16=10,8,0,0,625,22505,0,0,1049,62041,0,0,356,8042,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,12,130:4:0 0,12,120:4:0 +17 2993 . G 0 . DP=18;I16=10,8,0,0,646,23620,0,0,1049,62041,0,0,354,8050,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,118:4:0 0,12,123:4:0 +17 2994 . G 0 . DP=18;I16=10,8,0,0,620,21828,0,0,1049,62041,0,0,351,8025,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,30,254:10:0 0,12,115:4:0 0,12,116:4:0 +17 2995 . G 0 . DP=18;I16=10,8,0,0,628,22284,0,0,1049,62041,0,0,348,8018,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,12,110:4:0 0,12,135:4:0 +17 2996 . T 0 . DP=17;I16=8,8,0,0,497,16697,0,0,929,54841,0,0,323,7493,0,0;QS=3,0;MQSB=0.915545;MQ0F=0 PL:DP:DV 0,30,215:10:0 0,9,75:3:0 0,9,107:3:0 +17 2997 . C 0 . DP=17;I16=9,8,0,0,603,21925,0,0,989,58441,0,0,341,7901,0,0;QS=3,0;MQSB=0.928603;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,85:3:0 0,12,115:4:0 +17 2998 . C 0 . DP=17;I16=9,8,0,0,576,19964,0,0,989,58441,0,0,337,7841,0,0;QS=3,0;MQSB=0.928603;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,9,84:3:0 0,12,123:4:0 +17 2999 . A 0 . DP=17;I16=9,8,0,0,599,22077,0,0,989,58441,0,0,333,7797,0,0;QS=3,0;MQSB=0.928603;MQ0F=0 PL:DP:DV 0,30,238:10:0 0,9,109:3:0 0,12,136:4:0 +17 3000 . G 0 . DP=15;I16=8,7,0,0,554,20620,0,0,869,51241,0,0,331,7767,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,24,220:8:0 0,9,102:3:0 0,12,135:4:0 +17 3001 . C 0 . DP=15;I16=7,7,0,0,521,19695,0,0,809,47641,0,0,309,7349,0,0;QS=3,0;MQSB=0.885987;MQ0F=0 PL:DP:DV 0,21,213:7:0 0,9,103:3:0 0,12,128:4:0 +17 3002 . A 0 . DP=15;I16=8,7,0,0,542,20082,0,0,869,51241,0,0,326,7692,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,24,224:8:0 0,9,92:3:0 0,12,139:4:0 +17 3003 . G 0 . DP=15;I16=8,7,0,0,540,19814,0,0,869,51241,0,0,322,7594,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,24,230:8:0 0,9,96:3:0 0,12,120:4:0 +17 3004 . C 0 . DP=15;I16=8,7,0,0,525,19113,0,0,869,51241,0,0,318,7504,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,24,211:8:0 0,9,100:3:0 0,12,129:4:0 +17 3005 . A 0 . DP=14;I16=7,7,0,0,491,17343,0,0,809,47641,0,0,315,7421,0,0;QS=3,0;MQSB=0.885987;MQ0F=0 PL:DP:DV 0,21,197:7:0 0,9,95:3:0 0,12,124:4:0 +17 3006 . C 0 . DP=16;I16=7,8,0,0,516,18376,0,0,869,51241,0,0,312,7344,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,24,200:8:0 0,9,95:3:0 0,12,135:4:0 +17 3007 . C 0 . DP=16;I16=7,8,0,0,553,20853,0,0,869,51241,0,0,310,7274,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,24,214:8:0 0,9,103:3:0 0,12,144:4:0 +17 3008 . C 0 . DP=16;I16=7,8,0,0,576,22238,0,0,869,51241,0,0,308,7212,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,24,228:8:0 0,9,105:3:0 0,12,145:4:0 +17 3009 . A 0 . DP=16;I16=7,8,0,0,493,16739,0,0,869,51241,0,0,306,7158,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,24,200:8:0 0,9,83:3:0 0,12,130:4:0 +17 3010 . C 0 . DP=15;I16=7,7,0,0,534,20464,0,0,809,47641,0,0,300,7096,0,0;QS=3,0;MQSB=0.885987;MQ0F=0 PL:DP:DV 0,21,211:7:0 0,9,106:3:0 0,12,135:4:0 +17 3011 . A 0 . DP=16;I16=7,8,0,0,559,21173,0,0,869,51241,0,0,302,7074,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,24,218:8:0 0,9,104:3:0 0,12,145:4:0 +17 3012 . G 0 . DP=16;I16=7,8,0,0,503,17903,0,0,869,51241,0,0,300,7044,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,24,193:8:0 0,9,93:3:0 0,12,141:4:0 +17 3013 . C 0 . DP=16;I16=7,9,0,0,549,19967,0,0,898,52082,0,0,305,7071,0,0;QS=3,0;MQSB=0.994413;MQ0F=0 PL:DP:DV 0,27,207:9:0 0,9,98:3:0 0,12,141:4:0 +17 3014 . A 0 . DP=18;I16=6,9,0,0,542,20362,0,0,838,48482,0,0,289,6959,0,0;QS=3,0;MQSB=0.984496;MQ0F=0 PL:DP:DV 0,24,195:8:0 0,9,109:3:0 0,12,141:4:0 +17 3015 . G 0 . DP=20;I16=7,9,0,0,549,19441,0,0,929,54841,0,0,311,7547,0,0;QS=3,0;MQSB=0.892753;MQ0F=0 PL:DP:DV 0,24,206:8:0 0,12,116:4:0 0,12,131:4:0 +17 3016 . C 0 . DP=20;I16=7,13,0,0,690,24374,0,0,1138,66482,0,0,337,7783,0,0;QS=3,0;MQSB=0.972138;MQ0F=0 PL:DP:DV 0,33,248:11:0 0,15,136:5:0 0,12,132:4:0 +17 3017 . C A, 0 . DP=20;I16=7,12,0,1,650,23264,23,529,1109,65641,29,841,329,7715,11,121;QS=2.93801,0.0619946,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.972138;BQB=1;MQ0F=0 PL:DP:DV 0,10,224,30,227,236:11:1 0,15,133,15,133,133:5:0 0,12,128,12,128,128:4:0 +17 3018 . A 0 . DP=21;I16=6,10,0,0,475,15057,0,0,929,54841,0,0,295,6991,0,0;QS=3,0;MQSB=0.863243;MQ0F=0 PL:DP:DV 0,27,192:9:0 0,12,111:4:0 0,9,81:3:0 +17 3019 . C 0 . DP=20;I16=6,12,0,0,618,21842,0,0,1049,62041,0,0,336,7818,0,0;QS=3,0;MQSB=0.85394;MQ0F=0 PL:DP:DV 0,30,242:10:0 0,15,129:5:0 0,9,104:3:0 +17 3020 . C 0 . DP=20;I16=6,12,0,0,588,21046,0,0,1049,62041,0,0,340,7888,0,0;QS=3,0;MQSB=0.85394;MQ0F=0 PL:DP:DV 0,30,221:10:0 0,15,129:5:0 0,9,114:3:0 +17 3021 . T 0 . DP=21;I16=5,13,0,0,618,22454,0,0,1049,62041,0,0,343,7921,0,0;QS=3,0;MQSB=0.814433;MQ0F=0 PL:DP:DV 0,30,216:10:0 0,15,147:5:0 0,9,109:3:0 +17 3022 . G 0 . DP=20;I16=5,13,0,0,672,25292,0,0,1049,62041,0,0,348,7968,0,0;QS=3,0;MQSB=0.814433;MQ0F=0 PL:DP:DV 0,30,234:10:0 0,15,153:5:0 0,9,109:3:0 +17 3023 . T G, 0 . DP=20;I16=5,12,0,1,554,19110,18,324,989,58441,60,3600,336,7740,17,289;QS=2.94231,0.0576923,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.814433;BQB=1;MQ0F=0 PL:DP:DV 0,12,191,27,194,199:10:1 0,15,125,15,125,125:5:0 0,9,111,9,111,111:3:0 +17 3024 . G 0 . DP=20;I16=5,14,0,0,684,25122,0,0,1109,65641,0,0,382,8680,0,0;QS=3,0;MQSB=0.810584;MQ0F=0 PL:DP:DV 0,30,235:10:0 0,18,152:6:0 0,9,113:3:0 +17 3025 . G 0 . DP=20;I16=5,14,0,0,625,21465,0,0,1109,65641,0,0,386,8722,0,0;QS=3,0;MQSB=0.810584;MQ0F=0 PL:DP:DV 0,30,225:10:0 0,18,133:6:0 0,9,109:3:0 +17 3026 . C 0 . DP=20;I16=5,13,0,0,632,23132,0,0,1018,59282,0,0,367,8217,0,0;QS=3,0;MQSB=0.925212;MQ0F=0 PL:DP:DV 0,33,235:11:0 0,12,105:4:0 0,9,107:3:0 +17 3027 . A 0 . DP=21;I16=6,15,0,0,693,24199,0,0,1198,70082,0,0,413,9199,0,0;QS=3,0;MQSB=0.940481;MQ0F=0 PL:DP:DV 0,33,222:11:0 0,21,175:7:0 0,9,108:3:0 +17 3028 . G 0 . DP=21;I16=6,15,0,0,753,27935,0,0,1198,70082,0,0,417,9239,0,0;QS=3,0;MQSB=0.940481;MQ0F=0 PL:DP:DV 0,33,241:11:0 0,21,192:7:0 0,9,107:3:0 +17 3029 . G 0 . DP=21;I16=6,15,0,0,787,29949,0,0,1198,70082,0,0,421,9303,0,0;QS=3,0;MQSB=0.940481;MQ0F=0 PL:DP:DV 0,33,251:11:0 0,21,189:7:0 0,9,109:3:0 +17 3030 . G 0 . DP=22;I16=6,16,0,0,720,24728,0,0,1258,73682,0,0,424,9342,0,0;QS=3,0;MQSB=0.934321;MQ0F=0 PL:DP:DV 0,36,229:12:0 0,21,174:7:0 0,9,106:3:0 +17 3031 . A 0 . DP=22;I16=5,16,0,0,693,24631,0,0,1198,70082,0,0,403,8783,0,0;QS=3,0;MQSB=0.902014;MQ0F=0 PL:DP:DV 0,36,222:12:0 0,18,162:6:0 0,9,113:3:0 +17 3032 . G 0 . DP=22;I16=6,15,0,0,727,26093,0,0,1229,72841,0,0,405,8775,0,0;QS=3,0;MQSB=0.843281;MQ0F=0 PL:DP:DV 0,33,237:11:0 0,21,180:7:0 0,9,106:3:0 +17 3033 . G 0 . DP=22;I16=6,15,0,0,697,24039,0,0,1198,70082,0,0,429,9407,0,0;QS=3,0;MQSB=0.940481;MQ0F=0 PL:DP:DV 0,33,235:11:0 0,21,160:7:0 0,9,106:3:0 +17 3034 . A 0 . DP=23;I16=6,14,0,0,617,20947,0,0,1138,66482,0,0,387,8491,0,0;QS=3,0;MQSB=0.947033;MQ0F=0 PL:DP:DV 0,33,203:11:0 0,15,134:5:0 0,12,126:4:0 +17 3035 . G 0 . DP=23;I16=7,13,0,0,641,22007,0,0,1138,66482,0,0,385,8379,0,0;QS=3,0;MQSB=0.972138;MQ0F=0 PL:DP:DV 0,30,208:10:0 0,18,151:6:0 0,12,128:4:0 +17 3036 . C 0 . DP=23;I16=6,15,0,0,688,23652,0,0,1198,70082,0,0,388,8258,0,0;QS=3,0;MQSB=0.940481;MQ0F=0 PL:DP:DV 0,36,216:12:0 0,15,132:5:0 0,12,140:4:0 +17 3037 . T 0 . DP=24;I16=7,16,0,0,797,28671,0,0,1318,77282,0,0,439,9521,0,0;QS=3,0;MQSB=0.955805;MQ0F=0 PL:DP:DV 0,36,242:12:0 0,21,170:7:0 0,12,143:4:0 +17 3038 . T 0 . DP=25;I16=8,17,0,0,815,27469,0,0,1438,84482,0,0,441,9561,0,0;QS=3,0;MQSB=0.966223;MQ0F=0 PL:DP:DV 0,42,249:14:0 0,21,190:7:0 0,12,125:4:0 +17 3039 . G 0 . DP=25;I16=8,17,0,0,780,25946,0,0,1438,84482,0,0,444,9630,0,0;QS=3,0;MQSB=0.966223;MQ0F=0 PL:DP:DV 0,42,249:14:0 0,21,156:7:0 0,12,127:4:0 +17 3040 . T 0 . DP=25;I16=7,15,0,0,701,23777,0,0,1258,73682,0,0,385,8279,0,0;QS=3,0;MQSB=0.961028;MQ0F=0 PL:DP:DV 0,36,239:12:0 0,18,154:6:0 0,12,130:4:0 +17 3041 . G 0 . DP=25;I16=8,16,0,0,824,29228,0,0,1378,80882,0,0,420,8982,0,0;QS=3,0;MQSB=0.970446;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,186:7:0 0,12,135:4:0 +17 3042 . G 0 . DP=25;I16=8,15,0,0,795,28227,0,0,1349,80041,0,0,409,8839,0,0;QS=3,0;MQSB=0.889418;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,148:6:0 0,12,120:4:0 +17 3043 . T 0 . DP=25;I16=8,16,0,0,723,23191,0,0,1378,80882,0,0,435,9415,0,0;QS=3,0;MQSB=0.970446;MQ0F=0 PL:DP:DV 0,39,233:13:0 0,21,151:7:0 0,12,124:4:0 +17 3044 . A C, 0 . DP=26;I16=8,15,0,1,665,20809,15,225,1318,77282,60,3600,392,8498,14,196;QS=2.96104,0.038961,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.970446;BQB=1;MQ0F=0 PL:DP:DV 0,26,216,39,219,220:14:1 0,18,133,18,133,133:6:0 0,12,124,12,124,124:4:0 +17 3045 . C 0 . DP=26;I16=8,16,0,0,754,25232,0,0,1378,80882,0,0,403,8627,0,0;QS=3,0;MQSB=0.970446;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,133:6:0 0,12,122:4:0 +17 3046 . A 0 . DP=25;I16=8,15,0,0,748,26170,0,0,1349,80041,0,0,400,8540,0,0;QS=3,0;MQSB=0.889418;MQ0F=0 PL:DP:DV 0,39,245:13:0 0,18,160:6:0 0,12,141:4:0 +17 3047 . G 0 . DP=25;I16=8,15,0,0,766,26998,0,0,1318,77282,0,0,396,8432,0,0;QS=3,0;MQSB=0.974802;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,143:6:0 0,12,129:4:0 +17 3048 . T 0 . DP=25;I16=8,11,0,0,608,20554,0,0,1109,65641,0,0,320,6762,0,0;QS=3,0;MQSB=0.902014;MQ0F=0 PL:DP:DV 0,30,226:10:0 0,15,128:5:0 0,12,129:4:0 +17 3049 . G 0 . DP=24;I16=8,16,0,0,831,29557,0,0,1378,80882,0,0,426,9068,0,0;QS=3,0;MQSB=0.970446;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,161:6:0 0,9,105:3:0 +17 3050 . G 0 . DP=24;I16=8,14,0,0,729,25093,0,0,1258,73682,0,0,379,8041,0,0;QS=3,0;MQSB=0.979255;MQ0F=0 PL:DP:DV 0,39,253:13:0 0,18,159:6:0 0,9,100:3:0 +17 3051 . A 0 . DP=23;I16=8,15,0,0,724,24200,0,0,1318,77282,0,0,423,9091,0,0;QS=3,0;MQSB=0.974802;MQ0F=0 PL:DP:DV 0,42,243:14:0 0,18,152:6:0 0,9,103:3:0 +17 3052 . C 0 . DP=23;I16=7,13,0,0,612,19876,0,0,1169,69241,0,0,363,7779,0,0;QS=3,0;MQSB=0.962269;MQ0F=0 PL:DP:DV 0,36,226:12:0 0,15,117:5:0 0,9,93:3:0 +17 3053 . A 0 . DP=22;I16=8,11,0,0,616,21288,0,0,1078,62882,0,0,360,7740,0,0;QS=3,0;MQSB=0.992359;MQ0F=0 PL:DP:DV 0,33,234:11:0 0,15,118:5:0 0,9,110:3:0 +17 3054 . G 0 . DP=22;I16=8,14,0,0,761,27617,0,0,1258,73682,0,0,414,8932,0,0;QS=3,0;MQSB=0.979255;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,126:5:0 0,9,99:3:0 +17 3055 . G 0 . DP=22;I16=8,9,0,0,566,19890,0,0,958,55682,0,0,333,7219,0,0;QS=3,0;MQSB=0.998843;MQ0F=0 PL:DP:DV 0,30,228:10:0 0,12,111:4:0 0,9,105:3:0 +17 3056 . C 0 . DP=22;I16=7,14,0,0,701,24685,0,0,1198,70082,0,0,420,9298,0,0;QS=3,0;MQSB=0.966484;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,125:4:0 0,12,122:4:0 +17 3057 . C 0 . DP=23;I16=8,13,0,0,706,24988,0,0,1198,70082,0,0,411,9253,0,0;QS=3,0;MQSB=0.983744;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,128:5:0 0,9,92:3:0 +17 3058 . C 0 . DP=23;I16=9,14,0,0,707,23327,0,0,1318,77282,0,0,429,9471,0,0;QS=3,0;MQSB=0.987676;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,131:5:0 0,12,116:4:0 +17 3059 . T G, 0 . DP=23;I16=9,11,0,1,638,21954,16,256,1169,69241,60,3600,355,7761,22,484;QS=2.95876,0.0412371,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.913101;BQB=1;MQ0F=0 PL:DP:DV 0,22,234,36,237,239:13:1 0,15,144,15,144,144:5:0 0,9,94,9,94,94:3:0 +17 3060 . G 0 . DP=24;I16=9,10,0,0,578,19136,0,0,1109,65641,0,0,324,6992,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,33,221:11:0 0,12,121:4:0 0,12,116:4:0 +17 3061 . C 0 . DP=24;I16=9,15,0,0,770,25918,0,0,1378,80882,0,0,446,10136,0,0;QS=3,0;MQSB=0.984127;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,138:5:0 0,15,145:5:0 +17 3062 . C 0 . DP=23;I16=9,13,0,0,727,25019,0,0,1289,76441,0,0,419,9551,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,137:5:0 0,15,134:5:0 +17 3063 . C 0 . DP=23;I16=9,13,0,0,651,21695,0,0,1258,73682,0,0,415,9511,0,0;QS=3,0;MQSB=0.991121;MQ0F=0 PL:DP:DV 0,36,233:12:0 0,15,130:5:0 0,15,133:5:0 +17 3064 . A 0 . DP=23;I16=9,12,0,0,691,24125,0,0,1198,70082,0,0,385,8815,0,0;QS=3,0;MQSB=0.994334;MQ0F=0 PL:DP:DV 0,36,254:12:0 0,12,118:4:0 0,15,144:5:0 +17 3065 . G 0 . DP=22;I16=7,14,0,0,653,21733,0,0,1198,70082,0,0,426,9986,0,0;QS=3,0;MQSB=0.966484;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,109:4:0 0,12,118:4:0 +17 3066 . A 0 . DP=21;I16=7,10,0,0,501,16143,0,0,989,58441,0,0,326,7598,0,0;QS=3,0;MQSB=0.887766;MQ0F=0 PL:DP:DV 0,27,202:9:0 0,12,109:4:0 0,12,104:4:0 +17 3067 . T 0 . DP=21;I16=7,12,0,0,535,16779,0,0,1078,62882,0,0,373,8787,0,0;QS=3,0;MQSB=0.977926;MQ0F=0 PL:DP:DV 0,36,223:12:0 0,9,82:3:0 0,12,103:4:0 +17 3068 . G 0 . DP=20;I16=7,12,0,0,645,22781,0,0,1109,65641,0,0,396,9312,0,0;QS=3,0;MQSB=0.879351;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,115:4:0 0,9,84:3:0 +17 3069 . G 0 . DP=20;I16=7,10,0,0,468,14412,0,0,989,58441,0,0,346,8070,0,0;QS=3,0;MQSB=0.887766;MQ0F=0 PL:DP:DV 0,33,203:11:0 0,12,102:4:0 0,6,57:2:0 +17 3070 . C 0 . DP=20;I16=6,13,0,0,627,22135,0,0,1078,62882,0,0,414,9878,0,0;QS=3,0;MQSB=0.953977;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,98:3:0 0,9,98:3:0 +17 3071 . C 0 . DP=20;I16=7,13,0,0,715,26563,0,0,1138,66482,0,0,419,9893,0,0;QS=3,0;MQSB=0.972138;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,123:4:0 0,9,98:3:0 +17 3072 . C 0 . DP=20;I16=6,13,0,0,696,25784,0,0,1109,65641,0,0,414,9866,0,0;QS=3,0;MQSB=0.965977;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,128:4:0 0,9,106:3:0 +17 3073 . C 0 . DP=20;I16=6,13,0,0,706,26822,0,0,1109,65641,0,0,414,9872,0,0;QS=3,0;MQSB=0.965977;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,135:4:0 0,9,115:3:0 +17 3074 . C 0 . DP=20;I16=6,13,0,0,724,28052,0,0,1109,65641,0,0,414,9886,0,0;QS=3,0;MQSB=0.965977;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,135:4:0 0,9,116:3:0 +17 3075 . C 0 . DP=21;I16=6,13,0,0,630,21614,0,0,1109,65641,0,0,389,9283,0,0;QS=3,0;MQSB=0.965977;MQ0F=0 PL:DP:DV 0,33,239:11:0 0,15,140:5:0 0,9,94:3:0 +17 3076 . G 0 . DP=21;I16=6,14,0,0,645,21809,0,0,1169,69241,0,0,415,9939,0,0;QS=3,0;MQSB=0.969852;MQ0F=0 PL:DP:DV 0,36,252:12:0 0,15,126:5:0 0,9,91:3:0 +17 3077 . C 0 . DP=20;I16=5,15,0,0,694,25228,0,0,1169,69241,0,0,417,9979,0,0;QS=3,0;MQSB=0.976472;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,116:4:0 0,9,111:3:0 +17 3078 . C 0 . DP=20;I16=5,15,0,0,767,29761,0,0,1169,69241,0,0,420,10028,0,0;QS=3,0;MQSB=0.976472;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,113:4:0 0,9,111:3:0 +17 3079 . T 0 . DP=20;I16=5,15,0,0,749,28479,0,0,1169,69241,0,0,422,10038,0,0;QS=3,0;MQSB=0.976472;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,119:4:0 0,9,116:3:0 +17 3080 . G 0 . DP=21;I16=6,15,0,0,785,29901,0,0,1229,72841,0,0,424,10060,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,124:4:0 0,9,103:3:0 +17 3081 . C 0 . DP=21;I16=6,15,0,0,752,27438,0,0,1229,72841,0,0,425,9997,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,118:4:0 0,9,92:3:0 +17 3082 . C 0 . DP=21;I16=6,15,0,0,787,30211,0,0,1229,72841,0,0,426,9952,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,118:4:0 0,9,112:3:0 +17 3083 . T C, 0 . DP=21;I16=6,14,0,1,764,29458,33,1089,1169,69241,60,3600,401,9249,25,625;QS=2.93666,0.0633397,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.973096;BQB=1;MQ0F=0 PL:DP:DV 0,9,255,39,255,255:14:1 0,12,130,12,130,130:4:0 0,9,113,9,113,113:3:0 +17 3084 . G 0 . DP=23;I16=6,17,0,0,859,32755,0,0,1349,80041,0,0,426,9812,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,118:4:0 0,12,135:4:0 +17 3085 . T 0 . DP=23;I16=6,16,0,0,824,31132,0,0,1289,76441,0,0,426,9718,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,124:4:0 0,12,135:4:0 +17 3086 . G 0 . DP=23;I16=6,17,0,0,853,32429,0,0,1349,80041,0,0,428,9648,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,125:4:0 0,12,131:4:0 +17 3087 . G 0 . DP=23;I16=6,17,0,0,897,35253,0,0,1349,80041,0,0,429,9599,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,130:4:0 0,12,137:4:0 +17 3088 . A 0 . DP=22;I16=6,16,0,0,834,31738,0,0,1289,76441,0,0,431,9571,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,110:3:0 0,12,135:4:0 +17 3089 . A 0 . DP=23;I16=7,16,0,0,919,36903,0,0,1349,80041,0,0,432,9514,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,113:3:0 0,15,175:5:0 +17 3090 . G 0 . DP=23;I16=7,16,0,0,885,34349,0,0,1349,80041,0,0,433,9431,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,103:3:0 0,15,160:5:0 +17 3091 . T 0 . DP=23;I16=7,16,0,0,840,31352,0,0,1349,80041,0,0,434,9374,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,105:3:0 0,15,153:5:0 +17 3092 . T 0 . DP=24;I16=8,16,0,0,895,33673,0,0,1409,83641,0,0,434,9294,0,0;QS=3,0;MQSB=0.970446;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,109:3:0 0,15,165:5:0 +17 3093 . G 0 . DP=25;I16=9,16,0,0,955,37033,0,0,1469,87241,0,0,434,9192,0,0;QS=3,0;MQSB=0.968069;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,133:4:0 0,15,157:5:0 +17 3094 . A 0 . DP=25;I16=9,15,0,0,891,33319,0,0,1409,83641,0,0,425,9019,0,0;QS=3,0;MQSB=0.96464;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,134:4:0 0,15,161:5:0 +17 3095 . C 0 . DP=25;I16=9,15,0,0,891,33469,0,0,1409,83641,0,0,425,8955,0,0;QS=3,0;MQSB=0.96464;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,131:4:0 0,15,163:5:0 +17 3096 . C 0 . DP=25;I16=9,16,0,0,952,36626,0,0,1469,87241,0,0,436,9014,0,0;QS=3,0;MQSB=0.968069;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,121:4:0 0,15,167:5:0 +17 3097 . A 0 . DP=25;I16=9,16,0,0,972,38200,0,0,1469,87241,0,0,436,8984,0,0;QS=3,0;MQSB=0.968069;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,144:4:0 0,15,174:5:0 +17 3098 . G 0 . DP=25;I16=9,16,0,0,959,37269,0,0,1469,87241,0,0,436,8986,0,0;QS=3,0;MQSB=0.968069;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,134:4:0 0,15,166:5:0 +17 3099 . A 0 . DP=25;I16=9,16,0,0,888,32632,0,0,1469,87241,0,0,435,8971,0,0;QS=3,0;MQSB=0.968069;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,124:4:0 0,15,165:5:0 +17 3100 . C 0 . DP=25;I16=9,16,0,0,870,31084,0,0,1469,87241,0,0,434,8990,0,0;QS=3,0;MQSB=0.968069;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,126:4:0 0,15,159:5:0 +17 3101 . C 0 . DP=25;I16=9,16,0,0,960,37090,0,0,1469,87241,0,0,432,8992,0,0;QS=3,0;MQSB=0.968069;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,134:4:0 0,15,161:5:0 +17 3102 . A 0 . DP=26;I16=10,16,0,0,952,35186,0,0,1529,90841,0,0,430,9026,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,134:4:0 0,18,189:6:0 +17 3103 . T 0 . DP=26;I16=10,16,0,0,920,33094,0,0,1529,90841,0,0,427,8993,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,131:4:0 0,18,187:6:0 +17 3104 . C T, 0 . DP=25;I16=8,15,2,0,900,35584,80,3202,1349,80041,120,7200,385,8143,40,850;QS=2.58763,0.412371,0;VDB=0.8;SGB=0.346553;RPB=0.717391;MQB=0.956522;MQSB=0.962269;BQB=0.978261;MQ0F=0 PL:DP:DV 0,48,255,48,255,255:16:0 0,12,144,12,144,144:4:0 59,0,93,68,99,157:5:2 +17 3105 . T 0 . DP=25;I16=10,15,0,0,959,37057,0,0,1469,87241,0,0,422,8976,0,0;QS=3,0;MQSB=0.962269;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,149:4:0 0,15,169:5:0 +17 3106 . G 0 . DP=23;I16=10,13,0,0,881,33891,0,0,1380,82800,0,0,420,8940,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,132:4:0 0,15,167:5:0 +17 3107 . T 0 . DP=24;I16=10,14,0,0,878,32496,0,0,1440,86400,0,0,418,8932,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,132:4:0 0,18,195:6:0 +17 3108 . C 0 . DP=24;I16=10,14,0,0,909,34897,0,0,1440,86400,0,0,417,8953,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,137:4:0 0,18,189:6:0 +17 3109 . A 0 . DP=24;I16=10,14,0,0,905,34249,0,0,1440,86400,0,0,416,9004,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,136:4:0 0,18,195:6:0 +17 3110 . C 0 . DP=24;I16=10,13,0,0,919,37099,0,0,1380,82800,0,0,413,8933,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,105:3:0 0,18,189:6:0 +17 3111 . A 0 . DP=25;I16=10,14,0,0,961,38943,0,0,1440,86400,0,0,410,8888,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,111:3:0 0,18,205:6:0 +17 3112 . G 0 . DP=25;I16=10,14,0,0,958,39370,0,0,1440,86400,0,0,407,8821,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,116:3:0 0,18,191:6:0 +17 3113 . C 0 . DP=25;I16=10,14,0,0,961,39641,0,0,1440,86400,0,0,403,8735,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,112:3:0 0,18,193:6:0 +17 3114 . A 0 . DP=24;I16=10,13,0,0,928,38448,0,0,1380,82800,0,0,400,8680,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,116:3:0 0,18,200:6:0 +17 3115 . G 0 . DP=23;I16=10,12,0,0,872,35800,0,0,1320,79200,0,0,397,8603,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,117:3:0 0,18,195:6:0 +17 3116 . G 0 . DP=23;I16=10,12,0,0,870,35372,0,0,1320,79200,0,0,394,8552,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,108:3:0 0,18,194:6:0 +17 3117 . T 0 . DP=22;I16=9,13,0,0,771,27537,0,0,1320,79200,0,0,399,8575,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,96:3:0 0,18,177:6:0 +17 3118 . A 0 . DP=22;I16=9,13,0,0,813,30285,0,0,1320,79200,0,0,397,8537,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,111:3:0 0,18,193:6:0 +17 3119 . A 0 . DP=22;I16=9,13,0,0,886,35954,0,0,1320,79200,0,0,393,8423,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,120:3:0 0,18,207:6:0 +17 3120 . G 0 . DP=22;I16=9,13,0,0,839,32281,0,0,1320,79200,0,0,389,8333,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,104:3:0 0,18,182:6:0 +17 3121 . A 0 . DP=22;I16=10,12,0,0,777,28399,0,0,1320,79200,0,0,386,8266,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,111:3:0 0,18,194:6:0 +17 3122 . C 0 . DP=22;I16=10,12,0,0,848,33002,0,0,1320,79200,0,0,384,8222,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,110:3:0 0,18,192:6:0 +17 3123 . T 0 . DP=22;I16=10,12,0,0,854,33456,0,0,1320,79200,0,0,382,8202,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,114:3:0 0,18,204:6:0 +17 3124 . C 0 . DP=22;I16=10,11,0,0,882,38286,0,0,1260,75600,0,0,381,8205,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,104:3:0 0,15,178:5:0 +17 3125 . T 0 . DP=22;I16=10,11,0,0,860,36764,0,0,1260,75600,0,0,380,8230,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,106:3:0 0,15,185:5:0 +17 3126 . G 0 . DP=22;I16=10,11,0,0,834,34998,0,0,1260,75600,0,0,379,8277,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,97:3:0 0,15,174:5:0 +17 3127 . C 0 . DP=23;I16=10,11,0,0,847,36381,0,0,1260,75600,0,0,378,8346,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,87:3:0 0,15,175:5:0 +17 3128 . T 0 . DP=22;I16=9,12,0,0,850,35972,0,0,1229,72841,0,0,402,9010,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,107:3:0 0,15,182:5:0 +17 3129 . T 0 . DP=22;I16=9,12,0,0,809,32621,0,0,1229,72841,0,0,401,9067,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,107:3:0 0,15,178:5:0 +17 3130 . T 0 . DP=21;I16=9,10,0,0,744,30322,0,0,1140,68400,0,0,376,8516,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,82:2:0 0,15,169:5:0 +17 3131 . C 0 . DP=21;I16=9,10,0,0,792,34778,0,0,1140,68400,0,0,376,8606,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,83:2:0 0,15,170:5:0 +17 3132 . T 0 . DP=21;I16=9,11,0,0,819,35197,0,0,1169,69241,0,0,400,9288,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,109:3:0 0,15,174:5:0 +17 3133 . G 0 . DP=21;I16=9,11,0,0,800,34016,0,0,1169,69241,0,0,398,9312,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,97:3:0 0,15,166:5:0 +17 3134 . G 0 . DP=22;I16=10,11,0,0,773,30227,0,0,1229,72841,0,0,396,9352,0,0;QS=3,0;MQSB=0.939898;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,97:3:0 0,15,163:5:0 +17 3135 . G 0 . DP=22;I16=9,12,0,0,812,33714,0,0,1229,72841,0,0,396,9408,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,94:3:0 0,12,151:4:0 +17 3136 . C 0 . DP=22;I16=9,12,0,0,811,33469,0,0,1229,72841,0,0,396,9430,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,102:3:0 0,12,140:4:0 +17 3137 . A 0 . DP=22;I16=10,11,0,0,786,31226,0,0,1229,72841,0,0,396,9416,0,0;QS=3,0;MQSB=0.939898;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,95:3:0 0,12,142:4:0 +17 3138 . A 0 . DP=21;I16=9,11,0,0,720,28200,0,0,1169,69241,0,0,398,9414,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,98:3:0 0,12,147:4:0 +17 3139 . C 0 . DP=21;I16=9,11,0,0,755,31433,0,0,1169,69241,0,0,400,9424,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,91:3:0 0,12,139:4:0 +17 3140 . C 0 . DP=21;I16=9,11,0,0,790,33238,0,0,1169,69241,0,0,402,9446,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,102:3:0 0,12,145:4:0 +17 3141 . C 0 . DP=21;I16=9,11,0,0,819,35401,0,0,1169,69241,0,0,404,9480,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,101:3:0 0,12,150:4:0 +17 3142 . A 0 . DP=21;I16=9,11,0,0,822,35744,0,0,1169,69241,0,0,405,9477,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,107:3:0 0,12,155:4:0 +17 3143 . G 0 . DP=22;I16=10,11,0,0,846,36468,0,0,1198,70082,0,0,406,9488,0,0;QS=3,0;MQSB=0.99938;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,104:3:0 0,12,151:4:0 +17 3144 . C 0 . DP=23;I16=12,10,0,0,855,35905,0,0,1258,73682,0,0,409,9513,0,0;QS=3,0;MQSB=0.997828;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,104:3:0 0,15,165:5:0 +17 3145 . A 0 . DP=23;I16=12,10,0,0,869,35937,0,0,1258,73682,0,0,414,9554,0,0;QS=3,0;MQSB=0.997828;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,106:3:0 0,15,174:5:0 +17 3146 . G 0 . DP=23;I16=12,10,0,0,895,38345,0,0,1258,73682,0,0,419,9613,0,0;QS=3,0;MQSB=0.997828;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,105:3:0 0,15,179:5:0 +17 3147 . G 0 . DP=24;I16=11,11,0,0,851,34815,0,0,1289,76441,0,0,419,9623,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,123:4:0 0,15,172:5:0 +17 3148 . T 0 . DP=24;I16=12,11,0,0,795,30097,0,0,1318,77282,0,0,428,9682,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,107:4:0 0,15,149:5:0 +17 3149 . G 0 . DP=24;I16=12,11,0,0,910,38142,0,0,1318,77282,0,0,433,9743,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,120:4:0 0,15,167:5:0 +17 3150 . A 0 . DP=24;I16=12,11,0,0,854,33784,0,0,1318,77282,0,0,438,9822,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,129:4:0 0,15,167:5:0 +17 3151 . C 0 . DP=24;I16=12,11,0,0,873,35315,0,0,1318,77282,0,0,442,9870,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,125:4:0 0,15,163:5:0 +17 3152 . C 0 . DP=24;I16=12,11,0,0,857,34239,0,0,1318,77282,0,0,445,9889,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,123:4:0 0,15,155:5:0 +17 3153 . C 0 . DP=24;I16=12,11,0,0,891,36711,0,0,1318,77282,0,0,448,9930,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,125:4:0 0,15,166:5:0 +17 3154 . T 0 . DP=25;I16=13,11,0,0,938,38052,0,0,1378,80882,0,0,451,9993,0,0;QS=3,0;MQSB=0.998323;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,133:4:0 0,18,194:6:0 +17 3155 . G 0 . DP=25;I16=13,11,0,0,953,39423,0,0,1378,80882,0,0,454,10030,0,0;QS=3,0;MQSB=0.998323;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,127:4:0 0,18,180:6:0 +17 3156 . G 0 . DP=25;I16=13,11,0,0,946,38818,0,0,1378,80882,0,0,457,10093,0,0;QS=3,0;MQSB=0.998323;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,126:4:0 0,18,189:6:0 +17 3157 . A 0 . DP=24;I16=12,12,0,0,896,33648,0,0,1378,80882,0,0,486,10806,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,130:4:0 0,18,193:6:0 +17 3158 . A 0 . DP=24;I16=12,12,0,0,856,31670,0,0,1378,80882,0,0,490,10918,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,125:4:0 0,18,192:6:0 +17 3159 . T 0 . DP=24;I16=11,12,0,0,864,32952,0,0,1349,80041,0,0,477,10749,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,134:4:0 0,18,194:6:0 +17 3160 . T 0 . DP=24;I16=12,12,0,0,907,34719,0,0,1378,80882,0,0,494,11018,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,134:4:0 0,18,193:6:0 +17 3161 . C 0 . DP=24;I16=12,12,0,0,880,33336,0,0,1378,80882,0,0,494,11006,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,123:4:0 0,18,196:6:0 +17 3162 . C 0 . DP=24;I16=12,12,0,0,916,35764,0,0,1378,80882,0,0,494,11018,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,127:4:0 0,18,188:6:0 +17 3163 . T A, 0 . DP=24;I16=11,12,1,0,895,35099,13,169,1349,80041,29,841,473,10603,20,400;QS=2.97436,0.025641,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,28,255,39,255,255:14:1 0,12,137,12,137,137:4:0 0,18,200,18,200,200:6:0 +17 3164 . G 0 . DP=24;I16=12,11,0,0,887,34437,0,0,1349,80041,0,0,467,10385,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,106:3:0 0,18,188:6:0 +17 3165 . T 0 . DP=24;I16=12,12,0,0,880,32654,0,0,1378,80882,0,0,490,10990,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,133:4:0 0,18,189:6:0 +17 3166 . C 0 . DP=24;I16=12,11,0,0,871,33389,0,0,1349,80041,0,0,463,10369,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,111:3:0 0,18,193:6:0 +17 3167 . C 0 . DP=23;I16=12,11,0,0,879,34199,0,0,1318,77282,0,0,487,11021,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,131:4:0 0,18,189:6:0 +17 3168 . A 0 . DP=23;I16=12,11,0,0,874,33294,0,0,1318,77282,0,0,486,11070,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,125:4:0 0,18,192:6:0 +17 3169 . T 0 . DP=23;I16=11,11,0,0,824,31124,0,0,1289,76441,0,0,458,10416,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,128:4:0 0,18,187:6:0 +17 3170 . C 0 . DP=23;I16=11,11,0,0,877,35167,0,0,1289,76441,0,0,453,10307,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,129:4:0 0,18,201:6:0 +17 3171 . T 0 . DP=23;I16=11,11,0,0,843,32615,0,0,1289,76441,0,0,448,10216,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,127:4:0 0,18,201:6:0 +17 3172 . G 0 . DP=23;I16=12,11,0,0,813,29605,0,0,1318,77282,0,0,468,10768,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,120:4:0 0,18,176:6:0 +17 3173 . G 0 . DP=23;I16=11,11,0,0,801,29659,0,0,1289,76441,0,0,436,9988,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,126:4:0 0,18,174:6:0 +17 3174 . C 0 . DP=24;I16=13,11,0,0,938,36926,0,0,1378,80882,0,0,454,10476,0,0;QS=3,0;MQSB=0.998323;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,127:4:0 0,18,194:6:0 +17 3175 . A 0 . DP=25;I16=13,11,0,0,914,35230,0,0,1409,83641,0,0,422,9684,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,127:4:0 0,21,209:7:0 +17 3176 . G 0 . DP=24;I16=14,10,0,0,909,34913,0,0,1378,80882,0,0,442,10164,0,0;QS=3,0;MQSB=0.993166;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,97:3:0 0,21,205:7:0 +17 3177 . G 0 . DP=23;I16=14,9,0,0,793,28159,0,0,1318,77282,0,0,438,10040,0,0;QS=3,0;MQSB=0.987676;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,93:3:0 0,21,195:7:0 +17 3178 . T 0 . DP=23;I16=13,9,0,0,754,26290,0,0,1289,76441,0,0,408,9262,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,96:3:0 0,21,173:7:0 +17 3179 . G 0 . DP=23;I16=13,9,0,0,802,29686,0,0,1289,76441,0,0,403,9131,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,97:3:0 0,21,188:7:0 +17 3180 . G 0 . DP=22;I16=12,9,0,0,701,24107,0,0,1229,72841,0,0,398,8970,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,92:3:0 0,21,175:7:0 +17 3181 . G 0 . DP=22;I16=13,9,0,0,795,29503,0,0,1258,73682,0,0,418,9452,0,0;QS=3,0;MQSB=0.991121;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,99:3:0 0,21,193:7:0 +17 3182 . C 0 . DP=22;I16=12,9,0,0,772,28878,0,0,1198,70082,0,0,396,9038,0,0;QS=3,0;MQSB=0.994334;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,99:3:0 0,21,184:7:0 +17 3183 . A 0 . DP=22;I16=12,9,0,0,766,28304,0,0,1229,72841,0,0,382,8546,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,106:3:0 0,21,193:7:0 +17 3184 . T 0 . DP=21;I16=12,8,0,0,721,26533,0,0,1169,69241,0,0,377,8409,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,9,106:3:0 0,21,196:7:0 +17 3185 . T 0 . DP=20;I16=13,7,0,0,740,27660,0,0,1138,66482,0,0,397,8865,0,0;QS=3,0;MQSB=0.972138;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,103:3:0 0,18,174:6:0 +17 3186 . G 0 . DP=20;I16=13,7,0,0,741,28311,0,0,1138,66482,0,0,391,8665,0,0;QS=3,0;MQSB=0.972138;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,103:3:0 0,18,169:6:0 +17 3187 . A 0 . DP=20;I16=13,7,0,0,693,24927,0,0,1138,66482,0,0,385,8485,0,0;QS=3,0;MQSB=0.972138;MQ0F=0 PL:DP:DV 0,33,247:11:0 0,9,102:3:0 0,18,171:6:0 +17 3188 . A 0 . DP=20;I16=13,7,0,0,704,25746,0,0,1138,66482,0,0,379,8325,0,0;QS=3,0;MQSB=0.972138;MQ0F=0 PL:DP:DV 0,33,249:11:0 0,9,100:3:0 0,18,174:6:0 +17 3189 . A 0 . DP=21;I16=13,8,0,0,763,28171,0,0,1198,70082,0,0,373,8185,0,0;QS=3,0;MQSB=0.983744;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,125:4:0 0,18,174:6:0 +17 3190 . C 0 . DP=20;I16=11,8,0,0,675,24915,0,0,1109,65641,0,0,344,7440,0,0;QS=3,0;MQSB=0.902014;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,123:4:0 0,15,148:5:0 +17 3191 . T 0 . DP=21;I16=11,9,0,0,773,30203,0,0,1169,69241,0,0,340,7340,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,130:4:0 0,15,171:5:0 +17 3192 . G 0 . DP=21;I16=12,9,0,0,751,27785,0,0,1198,70082,0,0,362,7886,0,0;QS=3,0;MQSB=0.994334;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,125:4:0 0,15,152:5:0 +17 3193 . G 0 . DP=21;I16=12,9,0,0,756,27614,0,0,1198,70082,0,0,359,7829,0,0;QS=3,0;MQSB=0.994334;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,121:4:0 0,15,148:5:0 +17 3194 . T C, 0 . DP=21;I16=10,10,1,0,730,26992,18,324,1169,69241,29,841,332,7168,25,625;QS=2.95652,0.0434783,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.99938;BQB=1;MQ0F=0 PL:DP:DV 0,18,255,33,255,255:12:1 0,9,98,9,98,98:3:0 0,18,178,18,178,178:6:0 +17 3195 . T 0 . DP=21;I16=11,10,0,0,776,29184,0,0,1198,70082,0,0,356,7778,0,0;QS=3,0;MQSB=0.99938;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,95:3:0 0,18,189:6:0 +17 3196 . T 0 . DP=21;I16=10,10,0,0,722,26472,0,0,1169,69241,0,0,329,7111,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,91:3:0 0,18,186:6:0 +17 3197 . A 0 . DP=22;I16=12,9,0,0,715,24911,0,0,1229,72841,0,0,352,7718,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,103:3:0 0,18,179:6:0 +17 3198 . A 0 . DP=21;I16=12,8,0,0,745,28155,0,0,1169,69241,0,0,345,7675,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,105:3:0 0,18,198:6:0 +17 3199 . A 0 . DP=21;I16=11,9,0,0,736,27514,0,0,1200,72000,0,0,326,7080,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,105:3:0 0,18,196:6:0 +17 3200 . A 0 . DP=20;I16=11,9,0,0,735,27533,0,0,1169,69241,0,0,350,7660,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,108:3:0 0,18,195:6:0 +17 3201 . A 0 . DP=20;I16=11,8,0,0,706,26814,0,0,1109,65641,0,0,338,7486,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,9,107:3:0 0,18,198:6:0 +17 3202 . T 0 . DP=20;I16=10,9,0,0,692,25620,0,0,1140,68400,0,0,321,6907,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,9,109:3:0 0,18,187:6:0 +17 3203 . G A, 0 . DP=19;I16=9,9,1,0,644,23760,19,361,1080,64800,29,841,320,6872,25,625;QS=2.94823,0.0517711,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.934728;BQB=1;MQ0F=0 PL:DP:DV 0,14,239,30,242,248:11:1 0,9,105,9,105,105:3:0 0,15,160,15,160,160:5:0 +17 3204 . T 0 . DP=19;I16=9,8,0,0,619,22955,0,0,1020,61200,0,0,306,6686,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,234:9:0 0,9,101:3:0 0,15,169:5:0 +17 3205 . C 0 . DP=19;I16=9,9,0,0,672,25340,0,0,1080,64800,0,0,318,6856,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,99:3:0 0,15,157:5:0 +17 3206 . A 0 . DP=19;I16=10,9,0,0,661,23623,0,0,1109,65641,0,0,342,7500,0,0;QS=3,0;MQSB=0.934728;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,91:3:0 0,15,165:5:0 +17 3207 . C 0 . DP=19;I16=9,9,0,0,642,23618,0,0,1080,64800,0,0,316,6912,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,90:3:0 0,15,158:5:0 +17 3208 . A 0 . DP=18;I16=10,8,0,0,619,22023,0,0,1049,62041,0,0,341,7591,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,33,247:11:0 0,9,95:3:0 0,12,142:4:0 +17 3209 . C 0 . DP=19;I16=11,8,0,0,681,24747,0,0,1109,65641,0,0,340,7612,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,106:3:0 0,12,134:4:0 +17 3210 . C 0 . DP=18;I16=11,7,0,0,664,24900,0,0,1049,62041,0,0,340,7602,0,0;QS=3,0;MQSB=0.951002;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,101:3:0 0,12,141:4:0 +17 3211 . A 0 . DP=17;I16=11,6,0,0,645,24627,0,0,989,58441,0,0,341,7611,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,9,106:3:0 0,12,140:4:0 +17 3212 . T 0 . DP=17;I16=10,6,0,0,575,21295,0,0,960,57600,0,0,316,6964,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,222:9:0 0,9,100:3:0 0,12,144:4:0 +17 3213 . A 0 . DP=17;I16=10,6,0,0,597,22631,0,0,960,57600,0,0,316,6962,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,9,117:3:0 0,12,138:4:0 +17 3214 . G 0 . DP=17;I16=11,6,0,0,615,23103,0,0,989,58441,0,0,341,7605,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,9,110:3:0 0,12,134:4:0 +17 3215 . G 0 . DP=17;I16=11,6,0,0,591,21523,0,0,989,58441,0,0,340,7592,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,30,241:10:0 0,9,93:3:0 0,12,128:4:0 +17 3216 . C 0 . DP=17;I16=11,6,0,0,623,23303,0,0,989,58441,0,0,339,7597,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,30,242:10:0 0,9,94:3:0 0,12,138:4:0 +17 3217 . C 0 . DP=17;I16=11,6,0,0,570,19896,0,0,989,58441,0,0,337,7569,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,30,236:10:0 0,9,84:3:0 0,12,123:4:0 +17 3218 . G C, 0 . DP=18;I16=10,7,1,0,547,18185,29,841,1020,61200,29,841,310,6932,24,576;QS=2.91667,0.0833333,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.951002;BQB=1;MQ0F=0 PL:DP:DV 0,4,202,30,205,221:11:1 0,9,96,9,96,96:3:0 0,12,112,12,112,112:4:0 +17 3219 . G A, 0 . DP=18;I16=10,7,1,0,606,22158,19,361,1020,61200,29,841,308,6888,23,529;QS=2.94837,0.0516304,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.951002;BQB=1;MQ0F=0 PL:DP:DV 0,14,234,30,237,243:11:1 0,9,107,9,107,107:3:0 0,12,126,12,126,126:4:0 +17 3220 . G 0 . DP=18;I16=11,7,0,0,631,22827,0,0,1049,62041,0,0,326,7248,0,0;QS=3,0;MQSB=0.951002;MQ0F=0 PL:DP:DV 0,33,252:11:0 0,9,112:3:0 0,12,126:4:0 +17 3221 . C 0 . DP=17;I16=9,7,0,0,598,22586,0,0,960,57600,0,0,301,6659,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,9,103:3:0 0,12,139:4:0 +17 3222 . A 0 . DP=17;I16=10,7,0,0,623,23037,0,0,989,58441,0,0,318,6972,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,100:3:0 0,12,133:4:0 +17 3223 . C 0 . DP=17;I16=10,7,0,0,611,22603,0,0,989,58441,0,0,312,6764,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,96:3:0 0,12,132:4:0 +17 3224 . A 0 . DP=16;I16=10,6,0,0,609,23381,0,0,929,54841,0,0,307,6575,0,0;QS=3,0;MQSB=0.948436;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,9,97:3:0 0,12,141:4:0 +17 3225 . G 0 . DP=17;I16=11,6,0,0,604,22692,0,0,989,58441,0,0,302,6404,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,27,247:9:0 0,12,108:4:0 0,12,134:4:0 +17 3226 . T 0 . DP=18;I16=11,6,0,0,582,20466,0,0,1020,61200,0,0,282,5996,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,224:9:0 0,12,112:4:0 0,12,131:4:0 +17 3227 . G 0 . DP=18;I16=12,5,0,0,618,23008,0,0,989,58441,0,0,270,5496,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,91:3:0 0,12,125:4:0 +17 3228 . G 0 . DP=18;I16=11,6,0,0,611,22581,0,0,1020,61200,0,0,278,5816,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,248:9:0 0,12,118:4:0 0,12,121:4:0 +17 3229 . C 0 . DP=19;I16=12,7,0,0,686,25394,0,0,1109,65641,0,0,289,5925,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,118:4:0 0,12,126:4:0 +17 3230 . T 0 . DP=19;I16=12,6,0,0,669,25441,0,0,1049,62041,0,0,261,5187,0,0;QS=3,0;MQSB=0.961295;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,107:3:0 0,12,139:4:0 +17 3231 . C 0 . DP=19;I16=12,7,0,0,682,25046,0,0,1109,65641,0,0,283,5725,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,112:4:0 0,12,128:4:0 +17 3232 . A 0 . DP=19;I16=11,7,0,0,597,20779,0,0,1080,64800,0,0,270,5564,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,229:10:0 0,12,117:4:0 0,12,132:4:0 +17 3233 . C 0 . DP=19;I16=12,7,0,0,573,18239,0,0,1109,65641,0,0,277,5629,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,33,238:11:0 0,12,91:4:0 0,12,110:4:0 +17 3234 . G T, 0 . DP=19;I16=10,6,1,0,511,17305,22,484,960,57600,29,841,233,4849,8,64;QS=2.93855,0.0614525,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.955563;BQB=1;MQ0F=0 PL:DP:DV 0,11,222,30,225,234:11:1 0,6,63,6,63,63:2:0 0,12,100,12,100,100:4:0 +17 3235 . C 0 . DP=18;I16=12,6,0,0,625,22649,0,0,1049,62041,0,0,274,5582,0,0;QS=3,0;MQSB=0.961295;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,12,119:4:0 0,12,123:4:0 +17 3236 . C 0 . DP=18;I16=12,6,0,0,668,25124,0,0,1049,62041,0,0,273,5567,0,0;QS=3,0;MQSB=0.961295;MQ0F=0 PL:DP:DV 0,30,244:10:0 0,12,137:4:0 0,12,134:4:0 +17 3237 . T 0 . DP=17;I16=11,6,0,0,589,21235,0,0,989,58441,0,0,273,5573,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,27,230:9:0 0,12,102:4:0 0,12,136:4:0 +17 3238 . G 0 . DP=17;I16=11,6,0,0,609,22539,0,0,989,58441,0,0,273,5599,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,27,243:9:0 0,12,104:4:0 0,12,129:4:0 +17 3239 . T 0 . DP=17;I16=11,6,0,0,574,20204,0,0,989,58441,0,0,273,5645,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,27,220:9:0 0,12,107:4:0 0,12,131:4:0 +17 3240 . A 0 . DP=19;I16=12,7,0,0,624,21552,0,0,1109,65641,0,0,273,5711,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,33,248:11:0 0,12,101:4:0 0,12,132:4:0 +17 3241 . A 0 . DP=19;I16=11,6,0,0,619,23121,0,0,1020,61200,0,0,249,5173,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,9,96:3:0 0,12,143:4:0 +17 3242 . T 0 . DP=19;I16=12,7,0,0,655,23279,0,0,1140,68400,0,0,277,5911,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,12,104:4:0 0,15,152:5:0 +17 3243 . C 0 . DP=19;I16=12,7,0,0,682,25216,0,0,1140,68400,0,0,281,6047,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,111:4:0 0,15,148:5:0 +17 3244 . C 0 . DP=18;I16=11,6,0,0,587,21119,0,0,1020,61200,0,0,281,6139,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,12,116:4:0 0,15,142:5:0 +17 3245 . C 0 . DP=17;I16=10,7,0,0,631,23851,0,0,1020,61200,0,0,290,6282,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,12,126:4:0 0,12,131:4:0 +17 3246 . A 0 . DP=17;I16=10,7,0,0,646,24716,0,0,1020,61200,0,0,295,6427,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,12,129:4:0 0,12,139:4:0 +17 3247 . G 0 . DP=17;I16=10,7,0,0,606,22554,0,0,1020,61200,0,0,300,6590,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,12,92:4:0 0,12,133:4:0 +17 3248 . C 0 . DP=16;I16=10,6,0,0,603,23115,0,0,960,57600,0,0,306,6770,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,9,99:3:0 0,12,132:4:0 +17 3249 . C 0 . DP=16;I16=10,6,0,0,587,21913,0,0,960,57600,0,0,311,6917,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,246:9:0 0,9,99:3:0 0,12,133:4:0 +17 3250 . C 0 . DP=16;I16=10,6,0,0,616,24080,0,0,960,57600,0,0,316,7082,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,9,95:3:0 0,12,137:4:0 +17 3251 . T 0 . DP=16;I16=10,6,0,0,585,22193,0,0,960,57600,0,0,319,7165,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,9,104:3:0 0,12,135:4:0 +17 3252 . T 0 . DP=16;I16=10,6,0,0,553,19781,0,0,960,57600,0,0,321,7215,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,9,84:3:0 0,12,126:4:0 +17 3253 . T 0 . DP=16;I16=10,6,0,0,589,21933,0,0,960,57600,0,0,323,7281,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,245:9:0 0,9,102:3:0 0,12,132:4:0 +17 3254 . G 0 . DP=17;I16=10,7,0,0,631,23737,0,0,1020,61200,0,0,325,7363,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,9,100:3:0 0,15,154:5:0 +17 3255 . G 0 . DP=16;I16=9,7,0,0,554,20088,0,0,960,57600,0,0,328,7410,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,243:9:0 0,9,93:3:0 0,12,120:4:0 +17 3256 . G 0 . DP=16;I16=8,7,0,0,571,21985,0,0,900,54000,0,0,306,6846,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,6,62:2:0 0,12,142:4:0 +17 3257 . A 0 . DP=16;I16=9,7,0,0,585,21881,0,0,960,57600,0,0,334,7546,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,243:9:0 0,9,94:3:0 0,12,144:4:0 +17 3258 . G 0 . DP=17;I16=9,8,0,0,647,25407,0,0,1020,61200,0,0,337,7635,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,81:3:0 0,12,146:4:0 +17 3259 . G 0 . DP=17;I16=9,8,0,0,605,22237,0,0,1020,61200,0,0,341,7739,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,79:3:0 0,12,139:4:0 +17 3260 . C 0 . DP=17;I16=9,7,0,0,616,23908,0,0,960,57600,0,0,319,7183,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,6,64:2:0 0,12,133:4:0 +17 3261 . C 0 . DP=18;I16=9,9,0,0,655,24475,0,0,1080,64800,0,0,347,7891,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,90:3:0 0,12,138:4:0 +17 3262 . A 0 . DP=19;I16=10,9,0,0,712,27036,0,0,1140,68400,0,0,351,7989,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,123:4:0 0,12,148:4:0 +17 3263 . G 0 . DP=19;I16=10,9,0,0,715,27317,0,0,1140,68400,0,0,356,8104,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,116:4:0 0,12,146:4:0 +17 3264 . G 0 . DP=19;I16=10,9,0,0,676,24734,0,0,1140,68400,0,0,361,8237,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,93:4:0 0,12,143:4:0 +17 3265 . G 0 . DP=19;I16=10,9,0,0,701,26199,0,0,1140,68400,0,0,365,8339,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,109:4:0 0,12,137:4:0 +17 3266 . T 0 . DP=19;I16=9,9,0,0,597,20769,0,0,1080,64800,0,0,357,8229,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,82:4:0 0,9,113:3:0 +17 3267 . G 0 . DP=19;I16=10,9,0,0,659,24285,0,0,1140,68400,0,0,367,8299,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,76:4:0 0,12,133:4:0 +17 3268 . G 0 . DP=19;I16=10,9,0,0,668,24306,0,0,1140,68400,0,0,367,8255,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,92:4:0 0,12,142:4:0 +17 3269 . G 0 . DP=19;I16=10,9,0,0,714,27122,0,0,1140,68400,0,0,367,8227,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,115:4:0 0,12,137:4:0 +17 3270 . T 0 . DP=20;I16=10,9,0,0,606,20364,0,0,1140,68400,0,0,361,8141,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,251:11:0 0,12,83:4:0 0,12,136:4:0 +17 3271 . G 0 . DP=19;I16=10,9,0,0,709,26993,0,0,1140,68400,0,0,362,8108,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,100:4:0 0,12,143:4:0 +17 3272 . G 0 . DP=19;I16=10,9,0,0,672,24398,0,0,1140,68400,0,0,363,8093,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,97:4:0 0,12,140:4:0 +17 3273 . A 0 . DP=20;I16=10,10,0,0,735,27355,0,0,1200,72000,0,0,363,8047,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,153:5:0 0,12,147:4:0 +17 3274 . T 0 . DP=19;I16=9,10,0,0,699,26089,0,0,1140,68400,0,0,365,8021,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,142:5:0 0,12,149:4:0 +17 3275 . C 0 . DP=19;I16=9,10,0,0,727,28197,0,0,1140,68400,0,0,367,8015,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,137:5:0 0,12,139:4:0 +17 3276 . A 0 . DP=19;I16=9,10,0,0,681,25123,0,0,1140,68400,0,0,369,8029,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,15,150:5:0 0,12,141:4:0 +17 3277 . C 0 . DP=19;I16=9,10,0,0,733,28485,0,0,1140,68400,0,0,371,8063,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,153:5:0 0,12,146:4:0 +17 3278 . T 0 . DP=19;I16=9,10,0,0,737,28901,0,0,1140,68400,0,0,373,8117,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,168:5:0 0,12,153:4:0 +17 3279 . T 0 . DP=19;I16=9,10,0,0,714,27132,0,0,1140,68400,0,0,375,8191,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,148:5:0 0,12,150:4:0 +17 3280 . G 0 . DP=20;I16=9,11,0,0,758,29178,0,0,1200,72000,0,0,376,8234,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,143:5:0 0,12,146:4:0 +17 3281 . A 0 . DP=21;I16=10,11,0,0,822,32654,0,0,1260,75600,0,0,378,8296,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,179:6:0 0,12,157:4:0 +17 3282 . G 0 . DP=21;I16=10,11,0,0,815,32059,0,0,1260,75600,0,0,381,8379,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,173:6:0 0,12,150:4:0 +17 3283 . G 0 . DP=21;I16=10,11,0,0,790,30110,0,0,1260,75600,0,0,384,8484,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,161:6:0 0,12,146:4:0 +17 3284 . T 0 . DP=21;I16=10,11,0,0,748,27628,0,0,1260,75600,0,0,385,8511,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,155:6:0 0,12,146:4:0 +17 3285 . C 0 . DP=21;I16=10,11,0,0,776,29442,0,0,1260,75600,0,0,386,8560,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,169:6:0 0,12,143:4:0 +17 3286 . A 0 . DP=21;I16=10,11,0,0,826,32732,0,0,1260,75600,0,0,387,8631,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,187:6:0 0,12,153:4:0 +17 3287 . G 0 . DP=21;I16=10,11,0,0,804,31448,0,0,1260,75600,0,0,387,8673,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,164:6:0 0,12,150:4:0 +17 3288 . G 0 . DP=22;I16=10,11,0,0,754,27862,0,0,1260,75600,0,0,379,8635,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,141:5:0 0,15,164:5:0 +17 3289 . A 0 . DP=24;I16=13,11,0,0,897,34439,0,0,1440,86400,0,0,386,8714,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,166:6:0 0,15,178:5:0 +17 3290 . G 0 . DP=23;I16=12,10,0,0,832,31964,0,0,1320,79200,0,0,380,8684,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,112:4:0 0,15,168:5:0 +17 3291 . T 0 . DP=22;I16=11,9,0,0,707,25481,0,0,1200,72000,0,0,358,8112,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,95:3:0 0,15,168:5:0 +17 3292 . T 0 . DP=22;I16=13,9,0,0,783,28439,0,0,1320,79200,0,0,397,8929,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,127:5:0 0,15,164:5:0 +17 3293 . C 0 . DP=22;I16=13,9,0,0,852,33430,0,0,1320,79200,0,0,400,8992,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,136:5:0 0,15,170:5:0 +17 3294 . A 0 . DP=22;I16=13,9,0,0,818,30684,0,0,1320,79200,0,0,403,9077,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,145:5:0 0,15,162:5:0 +17 3295 . A 0 . DP=22;I16=14,8,0,0,820,31004,0,0,1320,79200,0,0,407,9183,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,140:5:0 0,12,143:4:0 +17 3296 . G 0 . DP=22;I16=14,8,0,0,837,32209,0,0,1320,79200,0,0,411,9259,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,133:5:0 0,12,140:4:0 +17 3297 . A 0 . DP=22;I16=14,8,0,0,787,28771,0,0,1320,79200,0,0,415,9355,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,134:5:0 0,12,140:4:0 +17 3298 . C 0 . DP=22;I16=13,9,0,0,826,31506,0,0,1320,79200,0,0,420,9470,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,113:4:0 0,12,135:4:0 +17 3299 . C 0 . DP=22;I16=13,9,0,0,857,33829,0,0,1320,79200,0,0,425,9553,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,117:4:0 0,12,140:4:0 +17 3300 . A 0 . DP=22;I16=13,9,0,0,861,33855,0,0,1320,79200,0,0,430,9654,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,134:4:0 0,12,144:4:0 +17 3301 . G 0 . DP=22;I16=13,9,0,0,869,34495,0,0,1320,79200,0,0,433,9675,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,131:4:0 0,12,141:4:0 +17 3302 . C 0 . DP=23;I16=14,9,0,0,863,32885,0,0,1380,82800,0,0,436,9718,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,115:4:0 0,15,155:5:0 +17 3303 . C 0 . DP=23;I16=14,9,0,0,887,34451,0,0,1380,82800,0,0,440,9784,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,125:4:0 0,15,153:5:0 +17 3304 . T 0 . DP=23;I16=14,9,0,0,886,34388,0,0,1380,82800,0,0,443,9825,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,134:4:0 0,15,167:5:0 +17 3305 . G 0 . DP=23;I16=14,9,0,0,878,33846,0,0,1380,82800,0,0,446,9892,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,119:4:0 0,15,151:5:0 +17 3306 . G 0 . DP=23;I16=14,9,0,0,886,34386,0,0,1380,82800,0,0,448,9934,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,127:4:0 0,15,150:5:0 +17 3307 . C 0 . DP=23;I16=14,8,0,0,812,30814,0,0,1320,79200,0,0,428,9508,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,116:4:0 0,15,153:5:0 +17 3308 . C 0 . DP=23;I16=14,9,0,0,835,31367,0,0,1380,82800,0,0,450,9986,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,118:4:0 0,15,151:5:0 +17 3309 . A 0 . DP=23;I16=14,9,0,0,875,33541,0,0,1380,82800,0,0,451,9995,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,128:4:0 0,15,162:5:0 +17 3310 . A 0 . DP=24;I16=15,9,0,0,882,32950,0,0,1440,86400,0,0,453,10027,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,152:5:0 0,15,164:5:0 +17 3311 . C 0 . DP=24;I16=15,9,0,0,913,35161,0,0,1440,86400,0,0,456,10084,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,145:5:0 0,15,157:5:0 +17 3312 . A 0 . DP=26;I16=16,9,0,0,950,36336,0,0,1500,90000,0,0,459,10167,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,153:5:0 0,15,160:5:0 +17 3313 . T 0 . DP=26;I16=16,10,0,0,987,37617,0,0,1560,93600,0,0,488,10902,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,180:6:0 0,15,161:5:0 +17 3314 . G 0 . DP=26;I16=16,10,0,0,1007,39401,0,0,1560,93600,0,0,491,10989,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,171:6:0 0,15,161:5:0 +17 3315 . G 0 . DP=26;I16=15,10,0,0,945,36073,0,0,1500,90000,0,0,484,10866,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,172:6:0 0,15,159:5:0 +17 3316 . T 0 . DP=26;I16=15,10,0,0,853,29881,0,0,1500,90000,0,0,464,10216,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,157:6:0 0,12,122:4:0 +17 3317 . G 0 . DP=27;I16=16,11,0,0,997,37431,0,0,1620,97200,0,0,488,10806,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,164:6:0 0,18,167:6:0 +17 3318 . A 0 . DP=26;I16=15,10,0,0,904,33212,0,0,1500,90000,0,0,481,10699,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,155:5:0 0,18,185:6:0 +17 3319 . A 0 . DP=25;I16=15,10,0,0,912,34090,0,0,1500,90000,0,0,482,10682,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,139:5:0 0,18,188:6:0 +17 3320 . A 0 . DP=25;I16=15,10,0,0,888,32722,0,0,1500,90000,0,0,483,10691,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,133:5:0 0,18,178:6:0 +17 3321 . C 0 . DP=25;I16=14,10,0,0,900,34142,0,0,1440,86400,0,0,471,10531,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,157:5:0 0,18,186:6:0 +17 3322 . C 0 . DP=25;I16=15,10,0,0,980,38582,0,0,1500,90000,0,0,483,10683,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,164:5:0 0,18,198:6:0 +17 3323 . C 0 . DP=25;I16=15,10,0,0,922,34948,0,0,1500,90000,0,0,483,10715,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,146:5:0 0,18,201:6:0 +17 3324 . C 0 . DP=25;I16=15,10,0,0,869,31271,0,0,1500,90000,0,0,482,10720,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,142:5:0 0,18,186:6:0 +17 3325 . G 0 . DP=25;I16=15,10,0,0,827,28293,0,0,1500,90000,0,0,481,10747,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,134:5:0 0,18,163:6:0 +17 3326 . T 0 . DP=24;I16=13,10,0,0,842,31362,0,0,1380,82800,0,0,464,10506,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,150:5:0 0,18,186:6:0 +17 3327 . C 0 . DP=24;I16=14,10,0,0,938,37076,0,0,1440,86400,0,0,481,10863,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,154:5:0 0,18,190:6:0 +17 3328 . T 0 . DP=25;I16=15,10,0,0,959,37033,0,0,1500,90000,0,0,480,10900,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,163:5:0 0,21,213:7:0 +17 3329 . A 0 . DP=24;I16=15,9,0,0,888,33082,0,0,1440,86400,0,0,481,10955,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,149:5:0 0,21,207:7:0 +17 3330 . C 0 . DP=25;I16=16,9,0,0,954,37064,0,0,1500,90000,0,0,481,10979,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,168:5:0 0,21,203:7:0 +17 3331 . T 0 . DP=25;I16=16,9,0,0,960,37332,0,0,1500,90000,0,0,482,11024,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,165:5:0 0,21,224:7:0 +17 3332 . A 0 . DP=25;I16=16,9,0,0,933,35065,0,0,1500,90000,0,0,483,11091,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,165:5:0 0,21,211:7:0 +17 3333 . A 0 . DP=26;I16=16,10,0,0,976,37344,0,0,1560,93600,0,0,483,11131,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,166:5:0 0,24,241:8:0 +17 3334 . A 0 . DP=25;I16=15,10,0,0,972,38210,0,0,1500,90000,0,0,485,11195,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,168:5:0 0,24,241:8:0 +17 3335 . A 0 . DP=25;I16=15,10,0,0,970,38200,0,0,1500,90000,0,0,486,11232,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,170:5:0 0,24,239:8:0 +17 3336 . A 0 . DP=25;I16=15,10,0,0,929,35277,0,0,1500,90000,0,0,485,11191,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,166:5:0 0,24,232:8:0 +17 3337 . T 0 . DP=25;I16=15,10,0,0,902,32856,0,0,1500,90000,0,0,484,11172,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,157:5:0 0,24,224:8:0 +17 3338 . A 0 . DP=25;I16=15,10,0,0,892,32056,0,0,1500,90000,0,0,481,11075,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,153:5:0 0,24,214:8:0 +17 3339 . C 0 . DP=25;I16=15,10,0,0,964,37444,0,0,1500,90000,0,0,478,11000,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,167:5:0 0,24,232:8:0 +17 3340 . A 0 . DP=23;I16=14,9,0,0,890,34616,0,0,1380,82800,0,0,477,10945,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,173:5:0 0,24,233:8:0 +17 3341 . A 0 . DP=23;I16=14,9,0,0,885,34459,0,0,1380,82800,0,0,476,10908,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,167:5:0 0,24,238:8:0 +17 3342 . A 0 . DP=23;I16=14,9,0,0,862,33262,0,0,1380,82800,0,0,475,10889,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,170:5:0 0,24,240:8:0 +17 3343 . A 0 . DP=22;I16=13,9,0,0,866,34280,0,0,1320,79200,0,0,474,10836,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,173:5:0 0,21,231:7:0 +17 3344 . A 0 . DP=22;I16=13,9,0,0,859,33731,0,0,1320,79200,0,0,473,10797,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,173:5:0 0,21,226:7:0 +17 3345 . T 0 . DP=22;I16=13,9,0,0,822,31100,0,0,1320,79200,0,0,472,10772,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,254:10:0 0,15,159:5:0 0,21,220:7:0 +17 3346 . T 0 . DP=22;I16=13,9,0,0,847,32679,0,0,1320,79200,0,0,470,10712,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,168:5:0 0,21,221:7:0 +17 3347 . A 0 . DP=23;I16=14,9,0,0,888,34650,0,0,1380,82800,0,0,468,10668,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,185:6:0 0,21,227:7:0 +17 3348 . G 0 . DP=23;I16=14,9,0,0,873,33609,0,0,1380,82800,0,0,467,10641,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,171:6:0 0,21,219:7:0 +17 3349 . C 0 . DP=24;I16=14,9,0,0,815,29785,0,0,1380,82800,0,0,465,10583,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,166:6:0 0,21,205:7:0 +17 3350 . C 0 . DP=24;I16=14,10,0,0,939,37249,0,0,1440,86400,0,0,464,10546,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,209:7:0 0,21,220:7:0 +17 3351 . T 0 . DP=24;I16=14,10,0,0,943,37255,0,0,1440,86400,0,0,463,10531,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,210:7:0 0,21,228:7:0 +17 3352 . G 0 . DP=24;I16=14,10,0,0,887,33267,0,0,1440,86400,0,0,462,10538,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,192:7:0 0,21,214:7:0 +17 3353 . G 0 . DP=24;I16=14,10,0,0,864,32092,0,0,1440,86400,0,0,461,10567,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,190:7:0 0,21,214:7:0 +17 3354 . C 0 . DP=24;I16=14,10,0,0,848,30714,0,0,1440,86400,0,0,459,10567,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,178:7:0 0,21,209:7:0 +17 3355 . G 0 . DP=23;I16=14,9,0,0,738,24386,0,0,1380,82800,0,0,457,10537,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,232:10:0 0,21,170:7:0 0,18,166:6:0 +17 3356 . T 0 . DP=23;I16=14,9,0,0,847,31689,0,0,1380,82800,0,0,454,10476,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,191:7:0 0,18,195:6:0 +17 3357 . G 0 . DP=23;I16=14,9,0,0,863,32919,0,0,1380,82800,0,0,449,10335,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,193:7:0 0,18,192:6:0 +17 3358 . G 0 . DP=22;I16=14,8,0,0,810,30184,0,0,1320,79200,0,0,445,10215,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,21,200:7:0 0,18,187:6:0 +17 3359 . T 0 . DP=23;I16=13,8,0,0,743,26737,0,0,1260,75600,0,0,404,9318,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,21,194:7:0 0,15,162:5:0 +17 3360 . G 0 . DP=23;I16=15,8,0,0,822,30058,0,0,1380,82800,0,0,436,9932,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,186:7:0 0,18,175:6:0 +17 3361 . G 0 . DP=22;I16=15,7,0,0,751,26793,0,0,1320,79200,0,0,433,9819,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,218:9:0 0,21,187:7:0 0,18,175:6:0 +17 3362 . C 0 . DP=22;I16=15,7,0,0,768,27462,0,0,1320,79200,0,0,430,9724,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,230:9:0 0,21,178:7:0 0,18,173:6:0 +17 3363 . G 0 . DP=21;I16=14,7,0,0,662,21572,0,0,1260,75600,0,0,428,9646,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,194:9:0 0,18,155:6:0 0,18,161:6:0 +17 3364 . C 0 . DP=21;I16=14,7,0,0,818,32184,0,0,1260,75600,0,0,423,9437,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,18,191:6:0 0,18,194:6:0 +17 3365 . A 0 . DP=21;I16=14,7,0,0,791,29983,0,0,1260,75600,0,0,418,9250,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,226:9:0 0,18,186:6:0 0,18,190:6:0 +17 3366 . T 0 . DP=21;I16=14,7,0,0,759,28053,0,0,1260,75600,0,0,413,9085,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,221:9:0 0,18,185:6:0 0,18,177:6:0 +17 3367 . G 0 . DP=21;I16=14,7,0,0,767,28539,0,0,1260,75600,0,0,408,8942,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,235:9:0 0,18,185:6:0 0,18,169:6:0 +17 3368 . C 0 . DP=21;I16=14,7,0,0,807,31329,0,0,1260,75600,0,0,403,8821,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,245:9:0 0,18,181:6:0 0,18,189:6:0 +17 3369 . C 0 . DP=21;I16=14,7,0,0,789,30271,0,0,1260,75600,0,0,398,8722,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,18,186:6:0 0,18,193:6:0 +17 3370 . T 0 . DP=21;I16=13,7,0,0,798,31960,0,0,1200,72000,0,0,392,8596,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,18,201:6:0 0,15,178:5:0 +17 3371 . G 0 . DP=20;I16=13,7,0,0,739,27875,0,0,1200,72000,0,0,387,8493,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,18,173:6:0 0,15,169:5:0 +17 3372 . T 0 . DP=20;I16=13,6,0,0,693,25677,0,0,1140,68400,0,0,359,7883,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,220:9:0 0,15,154:5:0 0,15,167:5:0 +17 3373 . A 0 . DP=20;I16=13,7,0,0,729,27019,0,0,1200,72000,0,0,375,8253,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,226:9:0 0,18,162:6:0 0,15,174:5:0 +17 3374 . A 0 . DP=19;I16=13,6,0,0,719,27437,0,0,1140,68400,0,0,369,8115,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,225:9:0 0,15,167:5:0 0,15,164:5:0 +17 3375 . T 0 . DP=20;I16=12,6,0,0,683,26039,0,0,1080,64800,0,0,337,7321,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,15,155:5:0 0,15,172:5:0 +17 3376 . C 0 . DP=20;I16=13,7,0,0,739,27867,0,0,1200,72000,0,0,356,7796,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,254:10:0 0,15,146:5:0 0,15,173:5:0 +17 3377 . C 0 . DP=20;I16=13,7,0,0,741,27905,0,0,1200,72000,0,0,350,7666,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,15,149:5:0 0,15,173:5:0 +17 3378 . C 0 . DP=20;I16=13,7,0,0,775,30179,0,0,1200,72000,0,0,343,7507,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,161:5:0 0,15,172:5:0 +17 3379 . A 0 . DP=20;I16=13,7,0,0,736,27530,0,0,1200,72000,0,0,336,7370,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,245:10:0 0,15,157:5:0 0,15,169:5:0 +17 3380 . G 0 . DP=19;I16=13,6,0,0,729,28249,0,0,1140,68400,0,0,330,7254,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,15,157:5:0 0,15,178:5:0 +17 3381 . C 0 . DP=19;I16=13,6,0,0,742,29288,0,0,1140,68400,0,0,324,7158,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,15,155:5:0 0,15,178:5:0 +17 3382 . T 0 . DP=17;I16=12,5,0,0,649,25245,0,0,1020,61200,0,0,320,7080,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,222:9:0 0,9,105:3:0 0,15,184:5:0 +17 3383 . A 0 . DP=17;I16=12,4,0,0,556,19808,0,0,960,57600,0,0,291,6393,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,196:9:0 0,6,71:2:0 0,15,167:5:0 +17 3384 . C 0 . DP=19;I16=14,5,0,0,701,26181,0,0,1140,68400,0,0,311,6923,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,235:10:0 0,9,98:3:0 0,18,187:6:0 +17 3385 . T 0 . DP=19;I16=14,5,0,0,730,28456,0,0,1140,68400,0,0,307,6797,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,237:10:0 0,9,109:3:0 0,18,195:6:0 +17 3386 . T 0 . DP=19;I16=14,5,0,0,642,22450,0,0,1140,68400,0,0,302,6642,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,197:10:0 0,9,104:3:0 0,18,188:6:0 +17 3387 . G 0 . DP=20;I16=14,6,0,0,723,26761,0,0,1200,72000,0,0,296,6460,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,230:10:0 0,9,105:3:0 0,21,210:7:0 +17 3388 . G 0 . DP=20;I16=14,6,0,0,705,25891,0,0,1200,72000,0,0,291,6303,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,225:10:0 0,9,109:3:0 0,21,202:7:0 +17 3389 . G 0 . DP=18;I16=10,7,0,0,617,22635,0,0,1020,61200,0,0,270,5808,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,190:7:0 0,9,105:3:0 0,21,207:7:0 +17 3390 . A 0 . DP=18;I16=11,7,0,0,631,22681,0,0,1080,64800,0,0,288,6056,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,200:8:0 0,9,105:3:0 0,21,198:7:0 +17 3391 . A 0 . DP=18;I16=11,7,0,0,663,24951,0,0,1080,64800,0,0,287,5965,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,192:8:0 0,9,113:3:0 0,21,224:7:0 +17 3392 . G 0 . DP=18;I16=11,7,0,0,666,25104,0,0,1080,64800,0,0,286,5896,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,211:8:0 0,9,103:3:0 0,21,216:7:0 +17 3393 . C 0 . DP=18;I16=11,7,0,0,686,26472,0,0,1080,64800,0,0,284,5800,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,222:8:0 0,9,106:3:0 0,21,214:7:0 +17 3394 . T 0 . DP=18;I16=11,7,0,0,699,27481,0,0,1080,64800,0,0,282,5728,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,219:8:0 0,9,114:3:0 0,21,222:7:0 +17 3395 . G 0 . DP=17;I16=10,7,0,0,656,25512,0,0,1020,61200,0,0,281,5679,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,205:7:0 0,9,105:3:0 0,21,222:7:0 +17 3396 . A 0 . DP=17;I16=10,7,0,0,644,25446,0,0,1020,61200,0,0,280,5652,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,182:7:0 0,9,119:3:0 0,21,232:7:0 +17 3397 . G 0 . DP=17;I16=10,7,0,0,633,23895,0,0,1020,61200,0,0,279,5647,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,193:7:0 0,9,107:3:0 0,21,218:7:0 +17 3398 . G 0 . DP=16;I16=10,6,0,0,610,23380,0,0,960,57600,0,0,279,5663,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,170:6:0 0,9,110:3:0 0,21,215:7:0 +17 3399 . G 0 . DP=17;I16=10,6,0,0,585,21729,0,0,960,57600,0,0,270,5618,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,147:5:0 0,12,122:4:0 0,21,216:7:0 +17 3400 . A 0 . DP=17;I16=10,6,0,0,576,21400,0,0,960,57600,0,0,264,5500,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,136:5:0 0,12,131:4:0 0,21,213:7:0 +17 3401 . T 0 . DP=17;I16=11,6,0,0,605,22159,0,0,1020,61200,0,0,280,5784,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,146:6:0 0,12,131:4:0 0,21,216:7:0 +17 3402 . G 0 . DP=17;I16=11,6,0,0,638,24150,0,0,1020,61200,0,0,280,5832,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,172:6:0 0,12,130:4:0 0,21,213:7:0 +17 3403 . A 0 . DP=16;I16=9,6,0,0,579,22815,0,0,900,54000,0,0,276,5874,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,139:5:0 0,12,140:4:0 0,18,205:6:0 +17 3404 . G 0 . DP=16;I16=10,6,0,0,564,20652,0,0,960,57600,0,0,281,5935,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,148:6:0 0,12,131:4:0 0,18,186:6:0 +17 3405 . A 0 . DP=16;I16=10,6,0,0,560,20158,0,0,960,57600,0,0,281,5991,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,157:6:0 0,12,124:4:0 0,18,179:6:0 +17 3406 . A 0 . DP=16;I16=10,6,0,0,568,20556,0,0,960,57600,0,0,281,6067,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,150:6:0 0,12,129:4:0 0,18,186:6:0 +17 3407 . C 0 . DP=17;I16=11,6,0,0,591,21225,0,0,1020,61200,0,0,281,6163,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,178:7:0 0,12,106:4:0 0,18,183:6:0 +17 3408 . T 0 . DP=17;I16=11,6,0,0,632,23754,0,0,1020,61200,0,0,282,6280,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,177:7:0 0,12,133:4:0 0,18,189:6:0 +17 3409 . G 0 . DP=16;I16=10,6,0,0,599,22667,0,0,960,57600,0,0,283,6369,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,172:6:0 0,12,119:4:0 0,18,192:6:0 +17 3410 . C 0 . DP=16;I16=10,6,0,0,585,21685,0,0,960,57600,0,0,282,6378,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,174:6:0 0,12,126:4:0 0,18,176:6:0 +17 3411 . T 0 . DP=15;I16=9,6,0,0,578,22492,0,0,900,54000,0,0,282,6404,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,165:6:0 0,9,114:3:0 0,18,196:6:0 +17 3412 . T 0 . DP=15;I16=9,6,0,0,546,20202,0,0,900,54000,0,0,283,6445,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,148:5:0 0,12,120:4:0 0,18,189:6:0 +17 3413 . G 0 . DP=15;I16=9,6,0,0,559,21023,0,0,900,54000,0,0,283,6401,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,158:5:0 0,12,124:4:0 0,18,184:6:0 +17 3414 . A 0 . DP=15;I16=9,6,0,0,512,17878,0,0,900,54000,0,0,283,6373,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,148:5:0 0,12,116:4:0 0,18,166:6:0 +17 3415 . A 0 . DP=16;I16=9,7,0,0,544,19656,0,0,960,57600,0,0,282,6310,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,142:5:0 0,12,132:4:0 0,21,179:7:0 +17 3416 . C 0 . DP=16;I16=9,7,0,0,562,20168,0,0,960,57600,0,0,282,6262,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,143:5:0 0,12,127:4:0 0,21,191:7:0 +17 3417 . C 0 . DP=16;I16=9,7,0,0,566,20666,0,0,960,57600,0,0,282,6230,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,147:5:0 0,12,126:4:0 0,21,192:7:0 +17 3418 . T 0 . DP=17;I16=10,5,0,0,557,21637,0,0,900,54000,0,0,268,5988,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,150:5:0 0,15,148:5:0 0,15,176:5:0 +17 3419 . G 0 . DP=17;I16=10,7,0,0,594,21642,0,0,1020,61200,0,0,310,6836,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,161:6:0 0,15,140:5:0 0,18,190:6:0 +17 3420 . G 0 . DP=17;I16=10,7,0,0,596,21580,0,0,1020,61200,0,0,312,6850,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,172:6:0 0,15,132:5:0 0,18,188:6:0 +17 3421 . G 0 . DP=18;I16=10,8,0,0,633,22781,0,0,1049,62041,0,0,314,6880,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,21,184:7:0 0,15,138:5:0 0,18,191:6:0 +17 3422 . A 0 . DP=18;I16=9,8,0,0,576,20954,0,0,989,58441,0,0,302,6702,0,0;QS=3,0;MQSB=0.91051;MQ0F=0 PL:DP:DV 0,18,167:6:0 0,15,130:5:0 0,18,188:6:0 +17 3423 . G 0 . DP=18;I16=9,9,0,0,651,24391,0,0,1049,62041,0,0,305,6747,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,21,200:7:0 0,15,149:5:0 0,18,183:6:0 +17 3424 . G 0 . DP=18;I16=8,8,0,0,555,20175,0,0,929,54841,0,0,275,6105,0,0;QS=3,0;MQSB=0.915545;MQ0F=0 PL:DP:DV 0,18,161:6:0 0,15,141:5:0 0,15,169:5:0 +17 3425 . C 0 . DP=18;I16=9,8,0,0,594,21676,0,0,1020,61200,0,0,307,6779,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,168:6:0 0,15,142:5:0 0,18,186:6:0 +17 3426 . A 0 . DP=18;I16=9,8,0,0,633,23967,0,0,1020,61200,0,0,308,6774,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,172:6:0 0,15,151:5:0 0,18,202:6:0 +17 3427 . G 0 . DP=18;I16=9,9,0,0,655,24639,0,0,1049,62041,0,0,315,6823,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,21,209:7:0 0,15,144:5:0 0,18,184:6:0 +17 3428 . A 0 . DP=18;I16=9,7,0,0,573,21235,0,0,960,57600,0,0,305,6793,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,158:5:0 0,15,147:5:0 0,18,178:6:0 +17 3429 . C 0 . DP=17;I16=8,9,0,0,516,16610,0,0,989,58441,0,0,320,6930,0,0;QS=3,0;MQSB=0.928603;MQ0F=0 PL:DP:DV 0,21,176:7:0 0,15,125:5:0 0,15,124:5:0 +17 3430 . G 0 . DP=18;I16=9,9,0,0,539,17155,0,0,1049,62041,0,0,323,7011,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,24,181:8:0 0,15,113:5:0 0,15,144:5:0 +17 3431 . T 0 . DP=18;I16=9,9,0,0,651,24101,0,0,1049,62041,0,0,327,7111,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,24,210:8:0 0,15,139:5:0 0,15,166:5:0 +17 3432 . T 0 . DP=18;I16=8,9,0,0,577,20601,0,0,989,58441,0,0,306,6606,0,0;QS=3,0;MQSB=0.928603;MQ0F=0 PL:DP:DV 0,21,162:7:0 0,15,144:5:0 0,15,165:5:0 +17 3433 . G 0 . DP=18;I16=9,9,0,0,623,22589,0,0,1049,62041,0,0,334,7320,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,24,199:8:0 0,15,138:5:0 0,15,164:5:0 +17 3434 . C 0 . DP=18;I16=10,7,0,0,582,20838,0,0,1020,61200,0,0,324,7208,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,208:8:0 0,15,130:5:0 0,12,137:4:0 +17 3435 . A 0 . DP=18;I16=10,8,0,0,595,21619,0,0,1049,62041,0,0,341,7453,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,27,185:9:0 0,15,150:5:0 0,12,151:4:0 +17 3436 . G 0 . DP=18;I16=10,8,0,0,617,22277,0,0,1049,62041,0,0,345,7549,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,27,218:9:0 0,15,146:5:0 0,12,133:4:0 +17 3437 . T G, 0 . DP=18;I16=10,7,0,1,594,21168,16,256,1020,61200,29,841,333,7409,16,256;QS=2.94286,0.0571429,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.906029;BQB=1;MQ0F=0 PL:DP:DV 0,11,188,24,191,195:9:1 0,15,148,15,148,148:5:0 0,12,132,12,132,132:4:0 +17 3438 . G 0 . DP=18;I16=10,7,0,0,622,23296,0,0,1020,61200,0,0,335,7461,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,215:8:0 0,15,152:5:0 0,12,140:4:0 +17 3439 . A 0 . DP=18;I16=10,8,0,0,619,22965,0,0,1049,62041,0,0,355,7853,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,27,215:9:0 0,15,153:5:0 0,12,132:4:0 +17 3440 . G 0 . DP=18;I16=10,7,0,0,610,22660,0,0,1020,61200,0,0,339,7613,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,15,143:5:0 0,12,131:4:0 +17 3441 . C 0 . DP=18;I16=10,6,0,0,585,22165,0,0,960,57600,0,0,315,7037,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,226:8:0 0,15,140:5:0 0,9,115:3:0 +17 3442 . T 0 . DP=20;I16=11,9,0,0,670,24716,0,0,1138,66482,0,0,362,8166,0,0;QS=3,0;MQSB=0.997118;MQ0F=0 PL:DP:DV 0,33,248:11:0 0,15,143:5:0 0,12,128:4:0 +17 3443 . G 0 . DP=20;I16=11,9,0,0,708,26092,0,0,1138,66482,0,0,366,8288,0,0;QS=3,0;MQSB=0.997118;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,143:5:0 0,12,137:4:0 +17 3444 . A 0 . DP=20;I16=11,9,0,0,698,25978,0,0,1138,66482,0,0,369,8379,0,0;QS=3,0;MQSB=0.997118;MQ0F=0 PL:DP:DV 0,33,244:11:0 0,15,161:5:0 0,12,131:4:0 +17 3445 . G 0 . DP=20;I16=11,9,0,0,718,26590,0,0,1138,66482,0,0,372,8488,0,0;QS=3,0;MQSB=0.997118;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,153:5:0 0,12,132:4:0 +17 3446 . A 0 . DP=20;I16=10,8,0,0,635,23323,0,0,1049,62041,0,0,325,7365,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,27,222:9:0 0,15,154:5:0 0,12,131:4:0 +17 3447 . T 0 . DP=20;I16=11,8,0,0,669,24331,0,0,1109,65641,0,0,352,8084,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,30,230:10:0 0,15,150:5:0 0,12,137:4:0 +17 3448 . C 0 . DP=19;I16=10,8,0,0,641,23693,0,0,1049,62041,0,0,355,8193,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,113:4:0 0,12,128:4:0 +17 3449 . A 0 . DP=19;I16=10,8,0,0,565,19185,0,0,1049,62041,0,0,357,8265,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,30,217:10:0 0,12,111:4:0 0,12,119:4:0 +17 3450 . C 0 . DP=18;I16=8,8,0,0,520,17846,0,0,898,52082,0,0,334,7674,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,229:10:0 0,6,70:2:0 0,12,106:4:0 +17 3451 . G 0 . DP=18;I16=10,7,0,0,528,17178,0,0,989,58441,0,0,361,8345,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,30,226:10:0 0,9,56:3:0 0,12,123:4:0 +17 3452 . C 0 . DP=18;I16=10,8,0,0,657,24597,0,0,1018,59282,0,0,388,9028,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,84:3:0 0,12,128:4:0 +17 3453 . C 0 . DP=18;I16=10,8,0,0,663,24951,0,0,1018,59282,0,0,390,9098,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,90:3:0 0,12,125:4:0 +17 3454 . A 0 . DP=18;I16=10,8,0,0,614,21898,0,0,1018,59282,0,0,392,9180,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,33,251:11:0 0,9,90:3:0 0,12,128:4:0 +17 3455 . C 0 . DP=18;I16=10,8,0,0,650,23968,0,0,1018,59282,0,0,394,9274,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,90:3:0 0,12,127:4:0 +17 3456 . T 0 . DP=18;I16=10,8,0,0,607,21961,0,0,1018,59282,0,0,395,9329,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,33,243:11:0 0,9,88:3:0 0,12,135:4:0 +17 3457 . G 0 . DP=18;I16=9,7,0,0,549,19861,0,0,898,52082,0,0,346,8144,0,0;QS=3,0;MQSB=0.994413;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,6,63:2:0 0,9,107:3:0 +17 3458 . C 0 . DP=18;I16=10,8,0,0,638,23236,0,0,1018,59282,0,0,397,9469,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,81:3:0 0,12,125:4:0 +17 3459 . A C, 0 . DP=17;I16=9,7,0,1,520,18390,22,484,929,54841,29,841,372,8830,25,625;QS=2.92971,0.0702875,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.998843;BQB=1;MQ0F=0 PL:DP:DV 0,8,201,27,204,213:10:1 0,9,84,9,84,84:3:0 0,12,116,12,116,116:4:0 +17 3460 . C 0 . DP=17;I16=8,7,0,0,554,20952,0,0,869,51241,0,0,345,8103,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,6,65:2:0 0,12,131:4:0 +17 3461 . T 0 . DP=17;I16=9,7,0,0,591,22805,0,0,929,54841,0,0,368,8638,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,27,231:9:0 0,9,103:3:0 0,12,133:4:0 +17 3462 . C 0 . DP=18;I16=9,9,0,0,672,25486,0,0,1018,59282,0,0,391,9185,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,90:3:0 0,12,130:4:0 +17 3463 . C 0 . DP=18;I16=8,9,0,0,584,21458,0,0,958,55682,0,0,369,8671,0,0;QS=3,0;MQSB=0.998843;MQ0F=0 PL:DP:DV 0,30,244:10:0 0,9,86:3:0 0,12,132:4:0 +17 3464 . A 0 . DP=18;I16=9,9,0,0,628,23490,0,0,1018,59282,0,0,387,8973,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,244:11:0 0,9,96:3:0 0,12,142:4:0 +17 3465 . G 0 . DP=19;I16=9,9,0,0,642,24008,0,0,1018,59282,0,0,384,8842,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,91:3:0 0,12,135:4:0 +17 3466 . C 0 . DP=20;I16=9,10,0,0,682,25218,0,0,1047,60123,0,0,378,8588,0,0;QS=3,0;MQSB=0.904084;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,101:3:0 0,15,147:5:0 +17 3467 . C 0 . DP=20;I16=10,9,0,0,685,25919,0,0,1047,60123,0,0,397,9139,0,0;QS=3,0;MQSB=0.948064;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,115:4:0 0,15,154:5:0 +17 3468 . T 0 . DP=20;I16=10,9,0,0,672,25426,0,0,1047,60123,0,0,374,8410,0,0;QS=3,0;MQSB=0.948064;MQ0F=0 PL:DP:DV 0,30,246:10:0 0,12,126:4:0 0,15,164:5:0 +17 3469 . G 0 . DP=21;I16=10,11,0,0,788,30064,0,0,1167,67323,0,0,396,8924,0,0;QS=3,0;MQSB=0.914611;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,146:5:0 0,15,163:5:0 +17 3470 . G 0 . DP=22;I16=11,11,0,0,796,29754,0,0,1196,68164,0,0,393,8781,0,0;QS=3,0;MQSB=0.770381;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,131:5:0 0,15,161:5:0 +17 3471 . G 0 . DP=23;I16=12,11,0,0,801,29083,0,0,1256,71764,0,0,391,8657,0,0;QS=3,0;MQSB=0.811552;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,133:5:0 0,15,151:5:0 +17 3472 . C 0 . DP=23;I16=12,11,0,0,757,26535,0,0,1256,71764,0,0,390,8554,0,0;QS=3,0;MQSB=0.811552;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,145:5:0 0,15,136:5:0 +17 3473 . A 0 . DP=23;I16=11,11,0,0,777,28175,0,0,1196,68164,0,0,379,8373,0,0;QS=3,0;MQSB=0.770381;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,148:5:0 0,15,153:5:0 +17 3474 . A 0 . DP=23;I16=12,11,0,0,807,29181,0,0,1256,71764,0,0,388,8414,0,0;QS=3,0;MQSB=0.811552;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,150:5:0 0,15,155:5:0 +17 3475 . C 0 . DP=22;I16=12,10,0,0,737,25849,0,0,1196,68164,0,0,387,8327,0,0;QS=3,0;MQSB=0.838545;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,137:5:0 0,15,143:5:0 +17 3476 . A 0 . DP=22;I16=12,10,0,0,790,29312,0,0,1196,68164,0,0,386,8262,0,0;QS=3,0;MQSB=0.838545;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,149:5:0 0,15,154:5:0 +17 3477 . G 0 . DP=22;I16=11,10,0,0,755,28237,0,0,1136,64564,0,0,363,7735,0,0;QS=3,0;MQSB=0.799507;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,126:4:0 0,15,153:5:0 +17 3478 . A 0 . DP=25;I16=13,11,0,0,857,31637,0,0,1316,75364,0,0,384,8198,0,0;QS=3,0;MQSB=0.845496;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,167:6:0 0,18,190:6:0 +17 3479 . G 0 . DP=25;I16=12,10,0,0,783,28623,0,0,1227,70923,0,0,355,7701,0,0;QS=3,0;MQSB=0.613159;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,152:5:0 0,18,160:6:0 +17 3480 . T 0 . DP=25;I16=13,11,0,0,788,27124,0,0,1316,75364,0,0,393,8531,0,0;QS=3,0;MQSB=0.845496;MQ0F=0 PL:DP:DV 0,33,249:11:0 0,21,182:7:0 0,18,155:6:0 +17 3481 . A 0 . DP=25;I16=12,12,0,0,858,30884,0,0,1347,78123,0,0,397,8685,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,194:7:0 0,15,148:5:0 +17 3482 . A 0 . DP=25;I16=13,12,0,0,927,35013,0,0,1376,78964,0,0,412,8942,0,0;QS=3,0;MQSB=0.822311;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,202:7:0 0,18,182:6:0 +17 3483 . G 0 . DP=25;I16=12,12,0,0,794,27410,0,0,1316,75364,0,0,412,9002,0,0;QS=3,0;MQSB=0.786628;MQ0F=0 PL:DP:DV 0,33,253:11:0 0,21,183:7:0 0,18,158:6:0 +17 3484 . A C, 0 . DP=24;I16=12,9,0,1,710,25220,14,196,1198,70082,60,3600,346,7514,25,625;QS=2.93665,0.0633484,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.804615;BQB=1;MQ0F=0 PL:DP:DV 0,30,227,30,227,227:10:0 0,7,156,18,159,162:7:1 0,15,133,15,133,133:5:0 +17 3485 . C 0 . DP=23;I16=11,11,0,0,766,27656,0,0,1196,68164,0,0,393,8573,0,0;QS=3,0;MQSB=0.770381;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,163:6:0 0,15,120:5:0 +17 3486 . T 0 . DP=24;I16=12,10,0,0,799,30529,0,0,1196,68164,0,0,398,8756,0,0;QS=3,0;MQSB=0.838545;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,198:7:0 0,15,128:5:0 +17 3487 . C 0 . DP=24;I16=10,11,0,0,724,27586,0,0,1167,67323,0,0,393,8905,0,0;QS=3,0;MQSB=0.914611;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,162:6:0 0,12,92:4:0 +17 3488 . T 0 . DP=24;I16=12,10,0,0,742,27454,0,0,1196,68164,0,0,429,9571,0,0;QS=3,0;MQSB=0.838545;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,172:7:0 0,12,98:4:0 +17 3489 . G 0 . DP=25;I16=13,11,0,0,778,28994,0,0,1285,72605,0,0,433,9675,0,0;QS=3,0;MQSB=0.97965;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,177:8:0 0,12,75:4:0 +17 3490 . T C, 0 . DP=27;I16=14,10,1,0,806,28886,25,625,1254,69846,60,3600,427,9659,12,144;QS=2.90775,0.0922509,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.962269;BQB=1;MQ0F=0 PL:DP:DV 0,39,255,39,255,255:13:0 0,2,168,24,171,183:9:1 0,9,85,9,85,85:3:0 +17 3491 . C 0 . DP=28;I16=15,11,0,0,864,31232,0,0,1405,79805,0,0,445,9903,0,0;QS=3,0;MQSB=0.753395;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,197:9:0 0,9,78:3:0 +17 3492 . T 0 . DP=28;I16=15,11,0,0,852,31516,0,0,1405,79805,0,0,452,9986,0,0;QS=3,0;MQSB=0.753395;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,212:9:0 0,9,96:3:0 +17 3493 . C 0 . DP=28;I16=15,12,0,0,891,32181,0,0,1434,80646,0,0,464,10124,0,0;QS=3,0;MQSB=0.908075;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,214:9:0 0,9,80:3:0 +17 3493 . CAAAAAAAAAAAAA CAAAAAAAAAAAA,CAAAAAAAAAAAAAA 0 . INDEL;IDV=2;IMF=0.125;DP=28;I16=9,9,0,2,443,11071,47,1129,1049,62041,89,4441,320,7120,30,650;QS=2.81818,0.0909091,0.0909091;VDB=0.504964;SGB=0.346553;MQSB=0.997118;MQ0F=0 PL:DP:DV 0,19,37,19,40,37:11:2 0,18,39,18,39,39:6:0 0,9,23,9,23,23:3:0 +17 3494 . A 0 . DP=30;I16=15,12,0,0,970,37408,0,0,1465,83405,0,0,440,9568,0,0;QS=3,0;MQSB=0.723173;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,220:9:0 0,12,117:4:0 +17 3495 . A 0 . DP=31;I16=15,13,0,0,966,36178,0,0,1525,87005,0,0,472,10270,0,0;QS=3,0;MQSB=0.695496;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,210:9:0 0,15,129:5:0 +17 3496 . A 0 . DP=31;I16=15,13,0,0,974,36928,0,0,1525,87005,0,0,477,10281,0,0;QS=3,0;MQSB=0.695496;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,207:9:0 0,15,138:5:0 +17 3497 . A 0 . DP=32;I16=14,14,0,0,1015,39525,0,0,1525,87005,0,0,460,9834,0,0;QS=3,0;MQSB=0.62781;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,208:8:0 0,18,148:6:0 +17 3498 . A 0 . DP=32;I16=14,14,0,0,982,37264,0,0,1556,89764,0,0,460,9628,0,0;QS=3,0;MQSB=0.813104;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,220:9:0 0,15,115:5:0 +17 3499 . A 0 . DP=32;I16=14,14,0,0,1024,40072,0,0,1525,87005,0,0,489,10267,0,0;QS=3,0;MQSB=0.62781;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,222:8:0 0,18,144:6:0 +17 3500 . A 0 . DP=31;I16=14,14,0,0,995,38097,0,0,1525,87005,0,0,494,10316,0,0;QS=3,0;MQSB=0.62781;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,214:8:0 0,18,150:6:0 +17 3501 . A 0 . DP=31;I16=14,14,0,0,1017,39845,0,0,1525,87005,0,0,499,10399,0,0;QS=3,0;MQSB=0.62781;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,221:8:0 0,18,149:6:0 +17 3502 . A 0 . DP=31;I16=14,14,0,0,1051,41955,0,0,1525,87005,0,0,504,10516,0,0;QS=3,0;MQSB=0.62781;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,223:8:0 0,18,154:6:0 +17 3503 . A 0 . DP=31;I16=14,14,0,0,1038,40832,0,0,1525,87005,0,0,509,10667,0,0;QS=3,0;MQSB=0.62781;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,229:8:0 0,18,155:6:0 +17 3504 . A 0 . DP=31;I16=14,14,0,0,1037,41235,0,0,1525,87005,0,0,512,10750,0,0;QS=3,0;MQSB=0.62781;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,229:8:0 0,18,145:6:0 +17 3505 . A 0 . DP=31;I16=14,14,0,0,1039,40959,0,0,1525,87005,0,0,514,10814,0,0;QS=3,0;MQSB=0.62781;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,233:8:0 0,18,156:6:0 +17 3506 . A 0 . DP=32;I16=11,13,0,0,889,34265,0,0,1378,80882,0,0,427,9079,0,0;QS=3,0;MQSB=0.998323;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,201:6:0 0,18,158:6:0 +17 3507 . T 0 . DP=31;I16=10,17,0,0,995,38431,0,0,1527,88923,0,0,493,10499,0,0;QS=3,0;MQSB=0.997168;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,187:6:0 0,18,153:6:0 +17 3508 . C 0 . DP=31;I16=10,17,0,0,997,40091,0,0,1527,88923,0,0,499,10675,0,0;QS=3,0;MQSB=0.997168;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,160:6:0 0,15,119:5:0 +17 3509 . A 0 . DP=30;I16=11,17,0,0,995,37147,0,0,1556,89764,0,0,529,11459,0,0;QS=3,0;MQSB=0.960952;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,175:6:0 0,15,125:5:0 +17 3510 . C A, 0 . DP=29;I16=9,17,1,0,959,37997,40,1600,1498,88082,29,841,483,10351,25,625;QS=2.95246,0.047541,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.997168;BQB=1;MQ0F=0 PL:DP:DV 0,19,255,45,255,255:16:1 0,18,150,18,150,150:6:0 0,15,119,15,119,119:5:0 +17 3511 . A 0 . DP=32;I16=11,17,0,0,923,33125,0,0,1587,92523,0,0,512,11150,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,169:6:0 0,15,115:5:0 +17 3512 . C 0 . DP=32;I16=10,18,0,0,1058,42208,0,0,1618,95282,0,0,493,10733,0,0;QS=3,0;MQSB=0.891417;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,181:6:0 0,15,131:5:0 +17 3513 . C A, 0 . DP=32;I16=10,18,1,0,1074,42406,13,169,1618,95282,29,841,498,10926,25,625;QS=2.98,0.02,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.995968;BQB=1;MQ0F=0 PL:DP:DV 0,39,255,51,255,255:18:1 0,18,190,18,190,190:6:0 0,15,136,15,136,136:5:0 +17 3514 . A 0 . DP=33;I16=11,19,0,0,1101,42213,0,0,1707,99723,0,0,528,11778,0,0;QS=3,0;MQSB=0.997918;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,199:7:0 0,15,132:5:0 +17 3515 . T 0 . DP=33;I16=12,19,0,0,1130,43380,0,0,1736,100564,0,0,557,12563,0,0;QS=3,0;MQSB=0.960505;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,192:7:0 0,15,126:5:0 +17 3516 . T 0 . DP=34;I16=14,17,0,0,1147,44331,0,0,1767,103323,0,0,536,12078,0,0;QS=3,0;MQSB=0.924242;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,203:7:0 0,15,133:5:0 +17 3517 . T 0 . DP=34;I16=14,18,0,0,1183,46549,0,0,1796,104164,0,0,565,12773,0,0;QS=3,0;MQSB=0.988522;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,210:7:0 0,15,153:5:0 +17 3518 . T 0 . DP=34;I16=14,18,0,0,1165,44867,0,0,1796,104164,0,0,568,12826,0,0;QS=3,0;MQSB=0.988522;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,203:7:0 0,15,141:5:0 +17 3519 . G 0 . DP=33;I16=13,18,0,0,1158,46678,0,0,1736,100564,0,0,572,12912,0,0;QS=3,0;MQSB=0.980167;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,18,189:6:0 0,15,154:5:0 +17 3520 . G 0 . DP=33;I16=12,18,0,0,1111,42471,0,0,1707,99723,0,0,552,12438,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,183:6:0 0,15,151:5:0 +17 3521 . C 0 . DP=32;I16=11,17,0,0,1077,43755,0,0,1649,98041,0,0,530,11850,0,0;QS=3,0;MQSB=0.967085;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,185:6:0 0,15,143:5:0 +17 3522 . T 0 . DP=32;I16=12,17,0,0,1125,46329,0,0,1678,98882,0,0,552,12274,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,199:6:0 0,15,158:5:0 +17 3523 . T 0 . DP=31;I16=11,16,0,0,996,38204,0,0,1558,91682,0,0,544,12286,0,0;QS=3,0;MQSB=0.992419;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,193:6:0 0,15,145:5:0 +17 3524 . C 0 . DP=31;I16=11,16,0,0,1067,43883,0,0,1589,94441,0,0,538,11960,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,192:6:0 0,15,152:5:0 +17 3525 . A 0 . DP=31;I16=13,16,0,0,1132,46402,0,0,1678,98882,0,0,556,12250,0,0;QS=3,0;MQSB=0.997839;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,200:6:0 0,15,165:5:0 +17 3526 . G 0 . DP=31;I16=12,16,0,0,1090,43912,0,0,1649,98041,0,0,543,12053,0,0;QS=3,0;MQSB=0.96195;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,181:6:0 0,15,147:5:0 +17 3527 . A 0 . DP=31;I16=13,16,0,0,1068,41740,0,0,1678,98882,0,0,560,12334,0,0;QS=3,0;MQSB=0.997839;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,170:6:0 0,15,157:5:0 +17 3528 . T 0 . DP=31;I16=13,16,0,0,1076,41782,0,0,1678,98882,0,0,561,12369,0,0;QS=3,0;MQSB=0.997839;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,193:6:0 0,15,152:5:0 +17 3529 . T 0 . DP=31;I16=12,16,0,0,1016,38674,0,0,1649,98041,0,0,550,12290,0,0;QS=3,0;MQSB=0.96195;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,184:6:0 0,15,154:5:0 +17 3530 . G 0 . DP=30;I16=12,17,0,0,1070,40570,0,0,1709,101641,0,0,578,13032,0,0;QS=3,0;MQSB=0.965321;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,176:6:0 0,18,175:6:0 +17 3531 . C A, 0 . DP=31;I16=13,17,1,0,1080,40304,38,1444,1738,102482,29,841,607,13801,10,100;QS=2.95773,0.0422741,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.924242;BQB=1;MQ0F=0 PL:DP:DV 0,28,255,54,255,255:19:1 0,18,172,18,172,172:6:0 0,18,175,18,175,175:6:0 +17 3532 . A 0 . DP=31;I16=14,17,0,0,1136,42380,0,0,1767,103323,0,0,619,14003,0,0;QS=3,0;MQSB=0.924242;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,180:6:0 0,18,184:6:0 +17 3533 . T 0 . DP=31;I16=13,17,0,0,1074,39206,0,0,1738,102482,0,0,595,13457,0,0;QS=3,0;MQSB=0.996503;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,180:6:0 0,18,176:6:0 +17 3534 . A 0 . DP=30;I16=12,17,0,0,1014,36168,0,0,1678,98882,0,0,597,13561,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,165:6:0 0,18,175:6:0 +17 3535 . T 0 . DP=31;I16=14,17,0,0,1042,36456,0,0,1767,103323,0,0,624,14314,0,0;QS=3,0;MQSB=0.924242;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,162:6:0 0,18,164:6:0 +17 3536 . C 0 . DP=31;I16=13,17,0,0,1102,41182,0,0,1738,102482,0,0,602,13842,0,0;QS=3,0;MQSB=0.996503;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,178:6:0 0,18,180:6:0 +17 3537 . C 0 . DP=32;I16=13,17,0,0,1142,43828,0,0,1769,105241,0,0,598,13854,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,194:7:0 0,18,185:6:0 +17 3538 . T 0 . DP=32;I16=14,17,0,0,1151,43471,0,0,1798,106082,0,0,603,13923,0,0;QS=3,0;MQSB=0.998229;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,211:7:0 0,18,185:6:0 +17 3539 . C 0 . DP=32;I16=12,17,0,0,1077,40959,0,0,1709,101641,0,0,600,13994,0,0;QS=3,0;MQSB=0.965321;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,170:6:0 0,18,173:6:0 +17 3540 . C 0 . DP=31;I16=13,17,0,0,1134,43546,0,0,1769,105241,0,0,603,14055,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,209:7:0 0,18,172:6:0 +17 3541 . T 0 . DP=32;I16=13,18,0,0,1143,42901,0,0,1829,108841,0,0,604,14134,0,0;QS=3,0;MQSB=0.966712;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,224:8:0 0,18,187:6:0 +17 3542 . G 0 . DP=32;I16=13,18,0,0,1152,43714,0,0,1829,108841,0,0,604,14134,0,0;QS=3,0;MQSB=0.966712;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,223:8:0 0,18,172:6:0 +17 3543 . C 0 . DP=31;I16=13,17,0,0,1142,43818,0,0,1769,105241,0,0,605,14153,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,221:8:0 0,18,188:6:0 +17 3544 . A 0 . DP=31;I16=13,17,0,0,1089,40065,0,0,1769,105241,0,0,606,14190,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,221:8:0 0,18,173:6:0 +17 3545 . A 0 . DP=30;I16=13,16,0,0,1118,43688,0,0,1709,101641,0,0,607,14195,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,228:7:0 0,18,196:6:0 +17 3546 . G 0 . DP=30;I16=14,16,0,0,1131,43425,0,0,1738,102482,0,0,630,14698,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,206:7:0 0,18,179:6:0 +17 3547 . G 0 . DP=31;I16=13,17,0,0,1076,39798,0,0,1769,105241,0,0,607,14163,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,189:7:0 0,18,187:6:0 +17 3548 . A 0 . DP=31;I16=13,17,0,0,1071,39059,0,0,1769,105241,0,0,608,14178,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,208:7:0 0,18,179:6:0 +17 3549 . T 0 . DP=30;I16=13,16,0,0,1008,35928,0,0,1678,98882,0,0,605,13989,0,0;QS=3,0;MQSB=0.997839;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,180:6:0 0,15,152:5:0 +17 3550 . A 0 . DP=30;I16=13,16,0,0,1061,39371,0,0,1709,101641,0,0,612,14270,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,194:7:0 0,15,173:5:0 +17 3551 . T 0 . DP=30;I16=13,16,0,0,1026,36844,0,0,1709,101641,0,0,613,14295,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,192:7:0 0,15,162:5:0 +17 3552 . A 0 . DP=30;I16=14,16,0,0,1080,39588,0,0,1738,102482,0,0,631,14627,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,202:7:0 0,15,158:5:0 +17 3553 . T A, 0 . DP=30;I16=13,16,1,0,1047,38333,20,400,1709,101641,29,841,616,14398,16,256;QS=2.96795,0.0320513,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.999136;BQB=1;MQ0F=0 PL:DP:DV 0,34,255,51,255,255:18:1 0,18,178,18,178,178:6:0 0,18,183,18,183,183:6:0 +17 3554 . A 0 . DP=30;I16=14,16,0,0,1063,38413,0,0,1738,102482,0,0,632,14602,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,185:6:0 0,18,179:6:0 +17 3555 . C 0 . DP=30;I16=14,16,0,0,1021,35781,0,0,1738,102482,0,0,632,14574,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,169:6:0 0,18,163:6:0 +17 3556 . G 0 . DP=30;I16=13,16,0,0,1014,36426,0,0,1709,101641,0,0,618,14350,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,168:6:0 0,18,173:6:0 +17 3557 . C 0 . DP=31;I16=14,16,0,0,1001,34919,0,0,1769,105241,0,0,618,14342,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,140:6:0 0,18,165:6:0 +17 3558 . G 0 . DP=31;I16=15,16,0,0,1036,35974,0,0,1798,106082,0,0,630,14476,0,0;QS=3,0;MQSB=0.999805;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,159:6:0 0,18,171:6:0 +17 3559 . T 0 . DP=30;I16=14,16,0,0,1086,40202,0,0,1769,105241,0,0,619,14341,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,171:6:0 0,18,192:6:0 +17 3560 . G 0 . DP=31;I16=14,16,0,0,1151,45035,0,0,1738,102482,0,0,611,14127,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,165:5:0 0,18,194:6:0 +17 3561 . A 0 . DP=31;I16=15,16,0,0,1147,43431,0,0,1798,106082,0,0,626,14366,0,0;QS=3,0;MQSB=0.999805;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,186:6:0 0,18,196:6:0 +17 3562 . A 0 . DP=31;I16=16,15,0,0,1157,43859,0,0,1798,106082,0,0,623,14257,0,0;QS=3,0;MQSB=0.999805;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,192:6:0 0,21,213:7:0 +17 3563 . A 0 . DP=31;I16=16,15,0,0,1162,44010,0,0,1798,106082,0,0,620,14124,0,0;QS=3,0;MQSB=0.999805;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,192:6:0 0,21,216:7:0 +17 3564 . T 0 . DP=31;I16=15,15,0,0,1132,43298,0,0,1769,105241,0,0,610,13932,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,192:6:0 0,21,214:7:0 +17 3565 . T 0 . DP=32;I16=16,16,0,0,1163,42649,0,0,1858,109682,0,0,611,13791,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,189:6:0 0,21,212:7:0 +17 3566 . C 0 . DP=32;I16=16,16,0,0,1162,43586,0,0,1858,109682,0,0,606,13596,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,181:6:0 0,21,209:7:0 +17 3567 . A 0 . DP=32;I16=15,16,0,0,1181,45245,0,0,1829,108841,0,0,597,13375,0,0;QS=3,0;MQSB=0.957006;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,192:6:0 0,21,222:7:0 +17 3568 . A 0 . DP=32;I16=15,16,0,0,1194,46670,0,0,1829,108841,0,0,592,13200,0,0;QS=3,0;MQSB=0.957006;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,204:6:0 0,21,228:7:0 +17 3569 . G 0 . DP=31;I16=15,16,0,0,1164,44544,0,0,1829,108841,0,0,586,13006,0,0;QS=3,0;MQSB=0.957006;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,180:6:0 0,21,204:7:0 +17 3570 . T 0 . DP=30;I16=14,15,0,0,1029,37527,0,0,1709,101641,0,0,572,12730,0,0;QS=3,0;MQSB=0.954405;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,136:4:0 0,21,213:7:0 +17 3571 . C 0 . DP=28;I16=13,15,0,0,1066,41192,0,0,1649,98041,0,0,568,12564,0,0;QS=3,0;MQSB=0.956162;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,138:4:0 0,21,215:7:0 +17 3572 . A 0 . DP=29;I16=13,16,0,0,1108,42566,0,0,1709,101641,0,0,564,12426,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,172:5:0 0,21,218:7:0 +17 3573 . A 0 . DP=29;I16=13,16,0,0,1119,43403,0,0,1709,101641,0,0,558,12168,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,174:5:0 0,21,220:7:0 +17 3574 . T 0 . DP=29;I16=13,16,0,0,1104,42220,0,0,1709,101641,0,0,552,11942,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,175:5:0 0,21,218:7:0 +17 3575 . G 0 . DP=29;I16=13,16,0,0,1122,43748,0,0,1709,101641,0,0,546,11748,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,161:5:0 0,21,212:7:0 +17 3576 . A 0 . DP=29;I16=13,16,0,0,1043,38405,0,0,1709,101641,0,0,540,11586,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,170:5:0 0,21,213:7:0 +17 3577 . C 0 . DP=30;I16=13,17,0,0,1123,42529,0,0,1769,105241,0,0,534,11456,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,161:5:0 0,21,211:7:0 +17 3578 . A 0 . DP=30;I16=13,17,0,0,1148,44236,0,0,1769,105241,0,0,529,11359,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,178:5:0 0,21,216:7:0 +17 3579 . A 0 . DP=29;I16=13,16,0,0,1051,38961,0,0,1709,101641,0,0,524,11244,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,172:5:0 0,18,192:6:0 +17 3580 . A 0 . DP=29;I16=13,16,0,0,1104,42344,0,0,1709,101641,0,0,519,11159,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,172:5:0 0,18,201:6:0 +17 3581 . T 0 . DP=29;I16=13,16,0,0,1088,41226,0,0,1709,101641,0,0,513,11055,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,161:5:0 0,18,199:6:0 +17 3582 . C 0 . DP=29;I16=13,16,0,0,1120,43616,0,0,1709,101641,0,0,506,10934,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,172:5:0 0,18,201:6:0 +17 3583 . A 0 . DP=30;I16=14,16,0,0,1130,43606,0,0,1769,105241,0,0,498,10796,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,183:5:0 0,21,213:7:0 +17 3584 . G 0 . DP=29;I16=12,16,0,0,1027,38895,0,0,1649,98041,0,0,487,10665,0,0;QS=3,0;MQSB=0.96195;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,137:4:0 0,21,209:7:0 +17 3585 . A 0 . DP=31;I16=14,17,0,0,1057,37719,0,0,1829,108841,0,0,486,10616,0,0;QS=3,0;MQSB=0.962133;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,168:5:0 0,24,209:8:0 +17 3586 . A 0 . DP=30;I16=14,15,0,0,1053,40043,0,0,1709,101641,0,0,477,10461,0,0;QS=3,0;MQSB=0.954405;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,174:5:0 0,24,213:8:0 +17 3587 . G A, 0 . DP=29;I16=4,7,10,6,426,16884,555,20381,660,39600,960,57600,192,4420,280,5942;QS=1.32665,1.67335,0;VDB=0.902044;SGB=-3.91326;RPB=0.800999;MQB=1;MQSB=1;BQB=0.156944;MQ0F=0 PL:DP:DV 161,0,184,182,205,255:14:7 22,0,118,34,121,148:5:1 212,24,0,212,24,212:8:8 +17 3588 . A 0 . DP=29;I16=14,14,0,0,999,36973,0,0,1680,100800,0,0,470,10254,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,166:5:0 0,24,215:8:0 +17 3589 . A 0 . DP=28;I16=14,13,0,0,967,35935,0,0,1620,97200,0,0,467,10173,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,166:5:0 0,24,206:8:0 +17 3590 . A 0 . DP=27;I16=13,13,0,0,948,35860,0,0,1560,93600,0,0,464,10072,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,146:4:0 0,24,211:8:0 +17 3591 . A 0 . DP=26;I16=13,13,0,0,913,33539,0,0,1560,93600,0,0,459,9901,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,144:4:0 0,24,212:8:0 +17 3592 . A 0 . DP=26;I16=13,13,0,0,893,32087,0,0,1560,93600,0,0,453,9711,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,143:4:0 0,24,199:8:0 +17 3593 . A 0 . DP=26;I16=13,13,0,0,891,31363,0,0,1560,93600,0,0,447,9553,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,137:4:0 0,24,198:8:0 +17 3594 . C 0 . DP=25;I16=12,12,0,0,910,34868,0,0,1440,86400,0,0,426,9170,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,142:4:0 0,24,216:8:0 +17 3595 . A 0 . DP=24;I16=13,11,0,0,918,35274,0,0,1440,86400,0,0,438,9328,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,143:4:0 0,21,199:7:0 +17 3596 . T 0 . DP=24;I16=13,11,0,0,837,30077,0,0,1440,86400,0,0,434,9258,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,138:4:0 0,21,188:7:0 +17 3597 . A 0 . DP=24;I16=13,11,0,0,893,33549,0,0,1440,86400,0,0,430,9216,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,132:4:0 0,21,204:7:0 +17 3598 . T 0 . DP=23;I16=12,10,0,0,778,28226,0,0,1320,79200,0,0,415,9005,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,140:4:0 0,21,162:7:0 +17 3599 . A 0 . DP=23;I16=13,10,0,0,859,32403,0,0,1380,82800,0,0,425,9105,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,142:4:0 0,21,182:7:0 +17 3600 . T 0 . DP=24;I16=14,10,0,0,872,32086,0,0,1435,85825,0,0,422,9036,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,139:4:0 0,21,183:7:0 +17 3601 . A 0 . DP=24;I16=14,10,0,0,862,31424,0,0,1435,85825,0,0,420,8994,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,132:4:0 0,21,186:7:0 +17 3602 . T 0 . DP=25;I16=15,10,0,0,873,31323,0,0,1495,89425,0,0,418,8980,0,0;QS=3,0;MQSB=0.962269;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,161:5:0 0,21,174:7:0 +17 3603 . A 0 . DP=26;I16=15,11,0,0,907,32447,0,0,1555,93025,0,0,416,8944,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,151:5:0 0,24,216:8:0 +17 3604 . C 0 . DP=27;I16=16,11,0,0,905,31199,0,0,1615,96625,0,0,415,8937,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,147:6:0 0,24,201:8:0 +17 3605 . G 0 . DP=27;I16=15,11,0,0,853,28887,0,0,1555,93025,0,0,393,8477,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,171:6:0 0,21,174:7:0 +17 3606 . C 0 . DP=27;I16=15,12,0,0,982,36756,0,0,1615,96625,0,0,415,8967,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,187:6:0 0,27,231:9:0 +17 3607 . A 0 . DP=26;I16=15,11,0,0,927,33859,0,0,1555,93025,0,0,417,9005,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,183:6:0 0,27,232:9:0 +17 3608 . A 0 . DP=27;I16=14,12,0,0,930,34054,0,0,1555,93025,0,0,394,8450,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,176:6:0 0,24,232:8:0 +17 3609 . A 0 . DP=27;I16=15,12,0,0,955,34701,0,0,1615,96625,0,0,421,9127,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,186:6:0 0,27,238:9:0 +17 3610 . C 0 . DP=27;I16=14,12,0,0,915,33071,0,0,1555,93025,0,0,397,8537,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,172:6:0 0,24,221:8:0 +17 3611 . C 0 . DP=25;I16=13,11,0,0,899,33995,0,0,1435,85825,0,0,398,8502,0,0;QS=3,0;MQSB=0.950498;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,173:6:0 0,24,234:8:0 +17 3612 . A 0 . DP=25;I16=14,11,0,0,957,37723,0,0,1495,89425,0,0,424,9118,0,0;QS=3,0;MQSB=0.955682;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,194:6:0 0,27,251:9:0 +17 3613 . G 0 . DP=26;I16=13,12,0,0,902,33110,0,0,1495,89425,0,0,399,8461,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,172:6:0 0,24,223:8:0 +17 3614 . T 0 . DP=26;I16=14,12,0,0,912,33340,0,0,1555,93025,0,0,425,9083,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,156:6:0 0,27,237:9:0 +17 3615 . A 0 . DP=26;I16=15,11,0,0,946,35138,0,0,1555,93025,0,0,427,9109,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,176:6:0 0,27,242:9:0 +17 3616 . T 0 . DP=26;I16=15,11,0,0,965,36541,0,0,1555,93025,0,0,431,9163,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,185:6:0 0,27,238:9:0 +17 3617 . C 0 . DP=25;I16=14,11,0,0,907,33675,0,0,1495,89425,0,0,436,9196,0,0;QS=3,0;MQSB=0.955682;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,176:6:0 0,24,215:8:0 +17 3618 . C 0 . DP=25;I16=14,11,0,0,964,37698,0,0,1495,89425,0,0,441,9259,0,0;QS=3,0;MQSB=0.955682;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,190:6:0 0,24,225:8:0 +17 3619 . T 0 . DP=25;I16=14,11,0,0,961,37553,0,0,1495,89425,0,0,446,9352,0,0;QS=3,0;MQSB=0.955682;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,194:6:0 0,24,238:8:0 +17 3620 . A 0 . DP=25;I16=14,11,0,0,880,31656,0,0,1495,89425,0,0,451,9475,0,0;QS=3,0;MQSB=0.955682;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,178:6:0 0,24,212:8:0 +17 3621 . C 0 . DP=25;I16=14,11,0,0,949,36561,0,0,1495,89425,0,0,456,9628,0,0;QS=3,0;MQSB=0.955682;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,182:6:0 0,24,230:8:0 +17 3622 . T 0 . DP=26;I16=15,11,0,0,983,38067,0,0,1555,93025,0,0,460,9762,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,194:7:0 0,24,242:8:0 +17 3623 . G 0 . DP=27;I16=16,11,0,0,969,35645,0,0,1615,96625,0,0,465,9929,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,195:7:0 0,24,209:8:0 +17 3624 . T 0 . DP=27;I16=15,11,0,0,948,35330,0,0,1555,93025,0,0,448,9596,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,188:6:0 0,24,224:8:0 +17 3625 . G 0 . DP=27;I16=14,12,0,0,983,37483,0,0,1555,93025,0,0,453,9735,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,210:7:0 0,24,219:8:0 +17 3626 . T 0 . DP=28;I16=15,12,0,0,998,37364,0,0,1615,96625,0,0,458,9854,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,214:7:0 0,27,229:9:0 +17 3627 . G 0 . DP=29;I16=15,13,0,0,999,36375,0,0,1675,100225,0,0,464,10004,0,0;QS=3,0;MQSB=0.956162;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,199:7:0 0,27,224:9:0 +17 3628 . T 0 . DP=29;I16=15,13,0,0,1033,38721,0,0,1675,100225,0,0,471,10187,0,0;QS=3,0;MQSB=0.956162;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,206:7:0 0,27,232:9:0 +17 3629 . G 0 . DP=29;I16=15,13,0,0,1058,40226,0,0,1675,100225,0,0,476,10304,0,0;QS=3,0;MQSB=0.956162;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,207:7:0 0,27,235:9:0 +17 3630 . T 0 . DP=30;I16=15,14,0,0,1052,39072,0,0,1735,103825,0,0,480,10404,0,0;QS=3,0;MQSB=0.954405;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,216:7:0 0,27,223:9:0 +17 3631 . C 0 . DP=29;I16=13,14,0,0,884,29476,0,0,1615,96625,0,0,461,9911,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,186:7:0 0,21,179:7:0 +17 3632 . G 0 . DP=29;I16=14,14,0,0,914,31068,0,0,1675,100225,0,0,491,10649,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,183:7:0 0,24,181:8:0 +17 3633 . T 0 . DP=29;I16=14,14,0,0,1022,38214,0,0,1675,100225,0,0,496,10792,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,216:7:0 0,24,222:8:0 +17 3634 . T 0 . DP=29;I16=14,14,0,0,1043,39891,0,0,1675,100225,0,0,500,10914,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,219:7:0 0,24,227:8:0 +17 3635 . T 0 . DP=28;I16=13,14,0,0,1029,39507,0,0,1615,96625,0,0,505,11063,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,219:7:0 0,24,224:8:0 +17 3636 . G 0 . DP=28;I16=13,14,0,0,1001,37681,0,0,1615,96625,0,0,510,11238,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,201:7:0 0,24,217:8:0 +17 3637 . T 0 . DP=27;I16=13,14,0,0,1019,39331,0,0,1615,96625,0,0,515,11439,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,212:7:0 0,24,240:8:0 +17 3638 . T 0 . DP=26;I16=12,14,0,0,967,36467,0,0,1555,93025,0,0,520,11616,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,185:6:0 0,24,222:8:0 +17 3639 . G 0 . DP=27;I16=13,14,0,0,997,37265,0,0,1615,96625,0,0,524,11768,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,183:6:0 0,27,221:9:0 +17 3640 . T 0 . DP=27;I16=13,14,0,0,1001,37533,0,0,1615,96625,0,0,527,11847,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,191:6:0 0,27,229:9:0 +17 3641 . G 0 . DP=27;I16=13,14,0,0,977,36379,0,0,1615,96625,0,0,529,11905,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,178:6:0 0,27,224:9:0 +17 3642 . T 0 . DP=26;I16=12,13,0,0,931,35169,0,0,1495,89425,0,0,506,11314,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,169:5:0 0,24,225:8:0 +17 3643 . T 0 . DP=26;I16=13,13,0,0,968,36820,0,0,1555,93025,0,0,533,11997,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,176:5:0 0,27,230:9:0 +17 3644 . T 0 . DP=26;I16=12,13,0,0,961,37477,0,0,1495,89425,0,0,517,11755,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,175:5:0 0,24,236:8:0 +17 3645 . T 0 . DP=26;I16=13,13,0,0,980,37508,0,0,1555,93025,0,0,537,12185,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,175:5:0 0,27,239:9:0 +17 3646 . C 0 . DP=26;I16=12,13,0,0,766,25026,0,0,1495,89425,0,0,514,11690,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,33,234:11:0 0,15,136:5:0 0,27,188:9:0 +17 3647 . G 0 . DP=26;I16=12,12,0,0,820,29600,0,0,1435,85825,0,0,492,11218,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,151:5:0 0,21,173:7:0 +17 3648 . A 0 . DP=26;I16=13,12,0,0,924,34680,0,0,1495,89425,0,0,519,11919,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,174:5:0 0,24,225:8:0 +17 3649 . C 0 . DP=26;I16=14,12,0,0,955,36105,0,0,1555,93025,0,0,545,12593,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,173:5:0 0,27,226:9:0 +17 3650 . A 0 . DP=27;I16=15,12,0,0,1033,40511,0,0,1615,96625,0,0,546,12664,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,196:6:0 0,27,246:9:0 +17 3651 . G 0 . DP=27;I16=15,12,0,0,1035,40351,0,0,1615,96625,0,0,547,12707,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,194:6:0 0,27,233:9:0 +17 3652 . C 0 . DP=29;I16=15,13,0,0,1010,38264,0,0,1675,100225,0,0,521,12047,0,0;QS=3,0;MQSB=0.956162;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,198:6:0 0,27,225:9:0 +17 3653 . T 0 . DP=29;I16=16,13,0,0,1109,42919,0,0,1735,103825,0,0,546,12610,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,202:6:0 0,27,239:9:0 +17 3654 . G 0 . DP=28;I16=14,12,0,0,981,37447,0,0,1555,93025,0,0,514,11882,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,184:6:0 0,18,180:6:0 +17 3655 . T 0 . DP=28;I16=16,12,0,0,999,37029,0,0,1675,100225,0,0,541,12505,0,0;QS=3,0;MQSB=0.96195;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,190:6:0 0,21,179:7:0 +17 3656 . C 0 . DP=28;I16=15,12,0,0,963,35883,0,0,1615,96625,0,0,518,11848,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,164:5:0 0,21,191:7:0 +17 3657 . C 0 . DP=28;I16=15,12,0,0,923,32223,0,0,1615,96625,0,0,520,11836,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,154:5:0 0,21,192:7:0 +17 3658 . G 0 . DP=28;I16=15,12,0,0,876,29960,0,0,1615,96625,0,0,539,12405,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,142:5:0 0,21,163:7:0 +17 3659 . T 0 . DP=28;I16=16,12,0,0,996,36682,0,0,1675,100225,0,0,548,12448,0,0;QS=3,0;MQSB=0.96195;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,163:6:0 0,21,186:7:0 +17 3660 . G 0 . DP=28;I16=15,12,0,0,997,37571,0,0,1615,96625,0,0,526,11920,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,172:6:0 0,18,171:6:0 +17 3661 . T 0 . DP=28;I16=16,12,0,0,1013,37837,0,0,1675,100225,0,0,549,12423,0,0;QS=3,0;MQSB=0.96195;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,180:6:0 0,21,188:7:0 +17 3662 . T 0 . DP=28;I16=15,12,0,0,987,36627,0,0,1615,96625,0,0,528,11980,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,182:6:0 0,18,184:6:0 +17 3663 . A 0 . DP=29;I16=16,12,0,0,997,36233,0,0,1675,100225,0,0,527,11959,0,0;QS=3,0;MQSB=0.96195;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,170:6:0 0,18,180:6:0 +17 3664 . T 0 . DP=29;I16=17,12,0,0,1044,38402,0,0,1735,103825,0,0,550,12490,0,0;QS=3,0;MQSB=0.965321;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,183:6:0 0,21,196:7:0 +17 3665 . A 0 . DP=27;I16=16,11,0,0,1017,38535,0,0,1615,96625,0,0,552,12510,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,182:6:0 0,21,208:7:0 +17 3666 . A 0 . DP=27;I16=16,11,0,0,1036,40292,0,0,1615,96625,0,0,554,12550,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,193:6:0 0,21,208:7:0 +17 3667 . T 0 . DP=27;I16=15,11,0,0,955,35895,0,0,1555,93025,0,0,540,12354,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,189:6:0 0,18,189:6:0 +17 3668 . A 0 . DP=27;I16=16,11,0,0,981,36297,0,0,1615,96625,0,0,557,12641,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,182:6:0 0,21,209:7:0 +17 3669 . A 0 . DP=27;I16=16,11,0,0,1030,39666,0,0,1615,96625,0,0,558,12694,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,194:6:0 0,21,209:7:0 +17 3670 . T 0 . DP=28;I16=17,11,0,0,1057,40245,0,0,1675,100225,0,0,559,12769,0,0;QS=3,0;MQSB=0.967085;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,181:6:0 0,24,220:8:0 +17 3671 . T 0 . DP=28;I16=17,11,0,0,1059,40427,0,0,1675,100225,0,0,561,12867,0,0;QS=3,0;MQSB=0.967085;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,193:6:0 0,24,223:8:0 +17 3672 . C 0 . DP=28;I16=16,11,0,0,988,37264,0,0,1615,96625,0,0,550,12820,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,169:6:0 0,21,205:7:0 +17 3673 . C 0 . DP=27;I16=16,10,0,0,1016,40148,0,0,1555,93025,0,0,528,12314,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,154:5:0 0,24,219:8:0 +17 3674 . T 0 . DP=27;I16=17,10,0,0,1035,40645,0,0,1615,96625,0,0,556,13028,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,155:5:0 0,24,228:8:0 +17 3675 . C 0 . DP=27;I16=17,10,0,0,1049,41413,0,0,1615,96625,0,0,558,13090,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,149:5:0 0,24,222:8:0 +17 3676 . T 0 . DP=27;I16=17,10,0,0,1040,40640,0,0,1615,96625,0,0,559,13125,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,159:5:0 0,24,231:8:0 +17 3677 . A 0 . DP=27;I16=16,10,0,0,922,34182,0,0,1555,93025,0,0,537,12557,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,136:5:0 0,24,217:8:0 +17 3678 . G 0 . DP=27;I16=17,10,0,0,1009,38307,0,0,1615,96625,0,0,563,13159,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,149:5:0 0,24,216:8:0 +17 3679 . T 0 . DP=27;I16=17,10,0,0,1018,39274,0,0,1615,96625,0,0,563,13105,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,156:5:0 0,24,227:8:0 +17 3680 . T 0 . DP=27;I16=17,10,0,0,988,36872,0,0,1615,96625,0,0,562,13022,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,157:5:0 0,24,202:8:0 +17 3681 . C 0 . DP=27;I16=17,10,0,0,1012,39154,0,0,1615,96625,0,0,560,12910,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,157:5:0 0,24,217:8:0 +17 3682 . A 0 . DP=27;I16=17,10,0,0,1009,38221,0,0,1615,96625,0,0,557,12769,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,156:5:0 0,24,220:8:0 +17 3683 . A 0 . DP=27;I16=17,9,0,0,966,36748,0,0,1555,93025,0,0,546,12552,0,0;QS=3,0;MQSB=0.971017;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,153:5:0 0,24,225:8:0 +17 3684 . A 0 . DP=26;I16=16,10,0,0,974,37440,0,0,1555,93025,0,0,550,12456,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,155:5:0 0,21,215:7:0 +17 3685 . T 0 . DP=26;I16=16,10,0,0,954,36330,0,0,1555,93025,0,0,547,12333,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,148:5:0 0,21,207:7:0 +17 3686 . T 0 . DP=26;I16=16,10,0,0,979,37645,0,0,1555,93025,0,0,544,12232,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,162:5:0 0,21,216:7:0 +17 3687 . T 0 . DP=27;I16=16,11,0,0,1028,39276,0,0,1592,94394,0,0,541,12153,0,0;QS=3,0;MQSB=0.989102;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,159:5:0 0,24,229:8:0 +17 3688 . A 0 . DP=28;I16=17,10,0,0,1007,37883,0,0,1569,92163,0,0,526,11904,0,0;QS=3,0;MQSB=0.99874;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,148:5:0 0,24,232:8:0 +17 3689 . T 0 . DP=28;I16=17,11,0,0,1042,39780,0,0,1629,95763,0,0,535,11919,0,0;QS=3,0;MQSB=0.995584;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,162:5:0 0,24,233:8:0 +17 3690 . T 0 . DP=28;I16=17,11,0,0,1051,39981,0,0,1629,95763,0,0,532,11816,0,0;QS=3,0;MQSB=0.995584;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,160:5:0 0,24,225:8:0 +17 3691 . C 0 . DP=28;I16=16,11,0,0,1037,40549,0,0,1569,92163,0,0,520,11592,0,0;QS=3,0;MQSB=0.992419;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,155:5:0 0,21,214:7:0 +17 3692 . A 0 . DP=29;I16=18,11,0,0,1028,37574,0,0,1689,99363,0,0,522,11496,0,0;QS=3,0;MQSB=0.99773;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,156:5:0 0,24,209:8:0 +17 3693 . T 0 . DP=28;I16=18,10,0,0,1067,40901,0,0,1629,95763,0,0,519,11381,0,0;QS=3,0;MQSB=0.999713;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,160:5:0 0,24,230:8:0 +17 3694 . T 0 . DP=28;I16=18,10,0,0,1043,39659,0,0,1629,95763,0,0,516,11296,0,0;QS=3,0;MQSB=0.999713;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,159:5:0 0,24,234:8:0 +17 3695 . T 0 . DP=28;I16=18,10,0,0,1046,39662,0,0,1629,95763,0,0,513,11241,0,0;QS=3,0;MQSB=0.999713;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,156:5:0 0,24,233:8:0 +17 3696 . T 0 . DP=28;I16=18,10,0,0,1075,41567,0,0,1629,95763,0,0,509,11165,0,0;QS=3,0;MQSB=0.999713;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,162:5:0 0,24,235:8:0 +17 3697 . T 0 . DP=28;I16=18,10,0,0,1031,38399,0,0,1629,95763,0,0,505,11117,0,0;QS=3,0;MQSB=0.999713;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,155:5:0 0,24,229:8:0 +17 3698 . A 0 . DP=28;I16=18,9,0,0,983,36457,0,0,1569,92163,0,0,477,10515,0,0;QS=3,0;MQSB=0.999669;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,144:5:0 0,24,229:8:0 +17 3699 . A 0 . DP=27;I16=17,10,0,0,1011,38455,0,0,1569,92163,0,0,493,10861,0,0;QS=3,0;MQSB=0.99874;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,150:5:0 0,21,226:7:0 +17 3700 . C 0 . DP=28;I16=16,11,0,0,970,35910,0,0,1574,92738,0,0,473,10525,0,0;QS=3,0;MQSB=0.992419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,168:6:0 0,24,212:8:0 +17 3701 . T 0 . DP=28;I16=17,11,0,0,1071,41669,0,0,1634,96338,0,0,484,10618,0,0;QS=3,0;MQSB=0.990092;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,196:6:0 0,24,233:8:0 +17 3702 . T 0 . DP=28;I16=17,10,0,0,1019,38653,0,0,1597,94969,0,0,462,10144,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,184:6:0 0,21,207:7:0 +17 3703 . C 0 . DP=28;I16=17,11,0,0,1059,40561,0,0,1634,96338,0,0,470,10154,0,0;QS=3,0;MQSB=0.990092;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,183:6:0 0,24,232:8:0 +17 3704 . A 0 . DP=28;I16=17,10,0,0,1015,38483,0,0,1574,92738,0,0,439,9347,0,0;QS=3,0;MQSB=0.984677;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,182:6:0 0,21,211:7:0 +17 3705 . T 0 . DP=27;I16=17,10,0,0,992,37112,0,0,1574,92738,0,0,459,9773,0,0;QS=3,0;MQSB=0.984677;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,180:6:0 0,21,209:7:0 +17 3706 . A 0 . DP=27;I16=17,10,0,0,1040,40262,0,0,1574,92738,0,0,454,9608,0,0;QS=3,0;MQSB=0.984677;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,186:6:0 0,21,204:7:0 +17 3707 . G 0 . DP=26;I16=17,9,0,0,974,37394,0,0,1514,89138,0,0,450,9476,0,0;QS=3,0;MQSB=0.977029;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,173:6:0 0,18,168:6:0 +17 3708 . T 0 . DP=26;I16=18,7,0,0,911,33609,0,0,1454,85538,0,0,426,8934,0,0;QS=3,0;MQSB=0.914166;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,182:6:0 0,15,139:5:0 +17 3709 . A 0 . DP=26;I16=18,8,0,0,905,32473,0,0,1491,86907,0,0,445,9305,0,0;QS=3,0;MQSB=0.998458;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,168:6:0 0,18,162:6:0 +17 3710 . C 0 . DP=26;I16=18,8,0,0,924,33504,0,0,1491,86907,0,0,443,9267,0,0;QS=3,0;MQSB=0.998458;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,165:6:0 0,18,159:6:0 +17 3711 . C 0 . DP=26;I16=18,8,0,0,953,35965,0,0,1491,86907,0,0,441,9261,0,0;QS=3,0;MQSB=0.998458;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,164:6:0 0,18,173:6:0 +17 3712 . A 0 . DP=26;I16=18,8,0,0,893,31917,0,0,1491,86907,0,0,439,9287,0,0;QS=3,0;MQSB=0.998458;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,144:6:0 0,18,165:6:0 +17 3713 . C 0 . DP=26;I16=19,7,0,0,908,32834,0,0,1491,86907,0,0,437,9293,0,0;QS=3,0;MQSB=0.989612;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,163:6:0 0,18,164:6:0 +17 3714 . A 0 . DP=27;I16=19,6,0,0,920,34366,0,0,1408,81076,0,0,409,8651,0,0;QS=3,0;MQSB=0.999494;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,177:6:0 0,18,174:6:0 +17 3715 . T 0 . DP=28;I16=21,6,0,0,982,36286,0,0,1505,86045,0,0,408,8616,0,0;QS=3,0;MQSB=0.996181;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,180:6:0 0,18,164:6:0 +17 3716 . T 0 . DP=26;I16=19,7,0,0,927,33833,0,0,1445,82445,0,0,434,9236,0,0;QS=3,0;MQSB=0.966731;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,165:5:0 0,18,164:6:0 +17 3717 . C 0 . DP=26;I16=19,7,0,0,979,37527,0,0,1445,82445,0,0,435,9261,0,0;QS=3,0;MQSB=0.966731;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,165:5:0 0,18,168:6:0 +17 3718 . T 0 . DP=26;I16=19,7,0,0,994,39040,0,0,1445,82445,0,0,435,9265,0,0;QS=3,0;MQSB=0.966731;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,169:5:0 0,18,165:6:0 +17 3719 . A 0 . DP=26;I16=19,6,0,0,889,32163,0,0,1408,81076,0,0,410,8672,0,0;QS=3,0;MQSB=0.747144;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,148:5:0 0,15,142:5:0 +17 3720 . C 0 . DP=26;I16=19,7,0,0,934,34326,0,0,1445,82445,0,0,435,9357,0,0;QS=3,0;MQSB=0.966731;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,148:5:0 0,18,158:6:0 +17 3721 . A 0 . DP=27;I16=20,5,0,0,910,33944,0,0,1405,80725,0,0,385,8195,0,0;QS=3,0;MQSB=0.697274;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,153:5:0 0,15,145:5:0 +17 3722 . C 0 . DP=27;I16=20,7,0,0,964,35276,0,0,1502,85694,0,0,436,9562,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,151:5:0 0,18,165:6:0 +17 3723 . A 0 . DP=25;I16=18,6,0,0,888,33516,0,0,1345,77125,0,0,414,9082,0,0;QS=3,0;MQSB=0.606531;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,134:4:0 0,15,145:5:0 +17 3724 . C 0 . DP=25;I16=18,7,0,0,944,35956,0,0,1382,78494,0,0,442,9878,0,0;QS=3,0;MQSB=0.889393;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,137:4:0 0,18,169:6:0 +17 3725 . T 0 . DP=25;I16=18,7,0,0,973,38263,0,0,1382,78494,0,0,445,10075,0,0;QS=3,0;MQSB=0.889393;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,138:4:0 0,18,190:6:0 +17 3726 . G 0 . DP=24;I16=18,6,0,0,865,32339,0,0,1322,74894,0,0,446,10146,0,0;QS=3,0;MQSB=0.934987;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,93:3:0 0,18,166:6:0 +17 3727 . C 0 . DP=22;I16=17,5,0,0,762,27812,0,0,1202,67694,0,0,447,10139,0,0;QS=3,0;MQSB=0.963102;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,82:3:0 0,15,143:5:0 +17 3728 . C 0 . DP=22;I16=17,5,0,0,792,29850,0,0,1202,67694,0,0,448,10154,0,0;QS=3,0;MQSB=0.963102;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,89:3:0 0,15,160:5:0 +17 3729 . C 0 . DP=22;I16=17,5,0,0,838,32312,0,0,1202,67694,0,0,449,10191,0,0;QS=3,0;MQSB=0.963102;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,93:3:0 0,15,164:5:0 +17 3730 . A 0 . DP=21;I16=17,4,0,0,749,27561,0,0,1142,64094,0,0,448,10100,0,0;QS=3,0;MQSB=0.995997;MQ0F=0 PL:DP:DV 0,39,241:13:0 0,9,98:3:0 0,15,159:5:0 +17 3731 . T 0 . DP=22;I16=18,4,0,0,787,29489,0,0,1152,64194,0,0,447,10031,0,0;QS=3,0;MQSB=0.967917;MQ0F=0 PL:DP:DV 0,42,253:14:0 0,9,101:3:0 0,15,139:5:0 +17 3732 . G 0 . DP=22;I16=18,4,0,0,811,30695,0,0,1152,64194,0,0,447,9985,0,0;QS=3,0;MQSB=0.967917;MQ0F=0 PL:DP:DV 0,42,252:14:0 0,9,101:3:0 0,15,149:5:0 +17 3733 . T 0 . DP=23;I16=19,4,0,0,820,29616,0,0,1212,67794,0,0,447,9963,0,0;QS=3,0;MQSB=0.979651;MQ0F=0 PL:DP:DV 0,45,248:15:0 0,9,101:3:0 0,15,152:5:0 +17 3734 . C 0 . DP=24;I16=20,4,0,0,863,32277,0,0,1272,71394,0,0,447,9915,0,0;QS=3,0;MQSB=0.988072;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,86:3:0 0,15,152:5:0 +17 3735 . C 0 . DP=24;I16=20,4,0,0,826,30112,0,0,1272,71394,0,0,448,9892,0,0;QS=3,0;MQSB=0.988072;MQ0F=0 PL:DP:DV 0,48,254:16:0 0,9,83:3:0 0,15,152:5:0 +17 3736 . C 0 . DP=25;I16=20,3,0,0,839,31471,0,0,1262,71294,0,0,419,9245,0,0;QS=3,0;MQSB=0.963194;MQ0F=0 PL:DP:DV 0,42,235:14:0 0,9,99:3:0 0,18,156:6:0 +17 3737 . C 0 . DP=25;I16=21,4,0,0,894,33402,0,0,1332,74994,0,0,451,9925,0,0;QS=3,0;MQSB=0.993838;MQ0F=0 PL:DP:DV 0,48,251:16:0 0,9,95:3:0 0,18,175:6:0 +17 3738 . T 0 . DP=25;I16=21,4,0,0,926,35484,0,0,1332,74994,0,0,452,9934,0,0;QS=3,0;MQSB=0.993838;MQ0F=0 PL:DP:DV 0,48,253:16:0 0,9,101:3:0 0,18,189:6:0 +17 3739 . C 0 . DP=25;I16=21,4,0,0,958,37390,0,0,1332,74994,0,0,452,9922,0,0;QS=3,0;MQSB=0.993838;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,105:3:0 0,18,181:6:0 +17 3740 . A 0 . DP=24;I16=20,4,0,0,848,31126,0,0,1272,71394,0,0,452,9886,0,0;QS=3,0;MQSB=0.988072;MQ0F=0 PL:DP:DV 0,48,247:16:0 0,9,109:3:0 0,15,163:5:0 +17 3741 . A 0 . DP=24;I16=19,4,0,0,814,30176,0,0,1212,67794,0,0,442,9742,0,0;QS=3,0;MQSB=0.979651;MQ0F=0 PL:DP:DV 0,48,238:16:0 0,6,82:2:0 0,15,172:5:0 +17 3742 . G 0 . DP=24;I16=20,4,0,0,893,34371,0,0,1272,71394,0,0,450,9782,0,0;QS=3,0;MQSB=0.988072;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,101:3:0 0,15,162:5:0 +17 3743 . C 0 . DP=24;I16=19,4,0,0,839,31673,0,0,1262,71294,0,0,437,9619,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,254:15:0 0,9,103:3:0 0,15,158:5:0 +17 3744 . T 0 . DP=24;I16=20,4,0,0,918,36126,0,0,1272,71394,0,0,448,9766,0,0;QS=3,0;MQSB=0.988072;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,118:3:0 0,15,164:5:0 +17 3745 . T 0 . DP=24;I16=19,4,0,0,808,29490,0,0,1212,67794,0,0,422,9166,0,0;QS=3,0;MQSB=0.979651;MQ0F=0 PL:DP:DV 0,45,233:15:0 0,9,108:3:0 0,15,158:5:0 +17 3746 . C 0 . DP=24;I16=20,4,0,0,886,33564,0,0,1272,71394,0,0,445,9789,0,0;QS=3,0;MQSB=0.988072;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,101:3:0 0,15,165:5:0 +17 3747 . C 0 . DP=24;I16=19,4,0,0,833,31071,0,0,1262,71294,0,0,426,9504,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,249:15:0 0,9,103:3:0 0,15,162:5:0 +17 3748 . C 0 . DP=24;I16=19,4,0,0,845,31753,0,0,1262,71294,0,0,422,9464,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,106:3:0 0,15,161:5:0 +17 3749 . C 0 . DP=24;I16=19,4,0,0,844,31888,0,0,1262,71294,0,0,417,9395,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,250:15:0 0,9,111:3:0 0,15,154:5:0 +17 3750 . T 0 . DP=25;I16=21,4,0,0,876,32880,0,0,1309,72763,0,0,431,9709,0,0;QS=3,0;MQSB=0.966906;MQ0F=0 PL:DP:DV 0,51,251:17:0 0,9,112:3:0 0,15,146:5:0 +17 3751 . G 0 . DP=24;I16=19,4,0,0,836,31374,0,0,1239,69063,0,0,408,9274,0,0;QS=3,0;MQSB=0.986928;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,82:2:0 0,15,162:5:0 +17 3752 . G 0 . DP=22;I16=19,2,0,0,728,26270,0,0,1069,58363,0,0,404,9134,0,0;QS=3,0;MQSB=0.868421;MQ0F=0 PL:DP:DV 0,42,182:14:0 0,6,74:2:0 0,15,159:5:0 +17 3753 . C 0 . DP=22;I16=19,3,0,0,761,28017,0,0,1129,61963,0,0,426,9674,0,0;QS=3,0;MQSB=0.995434;MQ0F=0 PL:DP:DV 0,45,213:15:0 0,6,61:2:0 0,15,163:5:0 +17 3754 . T 0 . DP=23;I16=19,3,0,0,767,28751,0,0,1129,61963,0,0,425,9707,0,0;QS=3,0;MQSB=0.995434;MQ0F=0 PL:DP:DV 0,45,218:15:0 0,6,69:2:0 0,15,157:5:0 +17 3755 . C 0 . DP=21;I16=16,4,0,0,749,28747,0,0,1028,55504,0,0,404,9188,0,0;QS=3,0;MQSB=0.777932;MQ0F=0 PL:DP:DV 0,36,219:12:0 0,9,93:3:0 0,15,161:5:0 +17 3756 . C 0 . DP=22;I16=17,4,0,0,782,29994,0,0,1038,55604,0,0,430,9840,0,0;QS=3,0;MQSB=0.885747;MQ0F=0 PL:DP:DV 0,39,229:13:0 0,9,93:3:0 0,15,159:5:0 +17 3757 . T 0 . DP=23;I16=17,6,0,0,828,30942,0,0,1158,62804,0,0,456,10510,0,0;QS=3,0;MQSB=0.9945;MQ0F=0 PL:DP:DV 0,39,210:13:0 0,15,143:5:0 0,15,169:5:0 +17 3758 . G 0 . DP=23;I16=17,6,0,0,832,30792,0,0,1158,62804,0,0,458,10574,0,0;QS=3,0;MQSB=0.9945;MQ0F=0 PL:DP:DV 0,39,220:13:0 0,15,135:5:0 0,15,147:5:0 +17 3759 . C 0 . DP=23;I16=17,4,0,0,756,28338,0,0,1061,57835,0,0,409,9357,0,0;QS=3,0;MQSB=0.964547;MQ0F=0 PL:DP:DV 0,39,220:13:0 0,12,112:4:0 0,12,127:4:0 +17 3760 . A 0 . DP=24;I16=17,7,0,0,792,27956,0,0,1218,66404,0,0,459,10607,0,0;QS=3,0;MQSB=0.95083;MQ0F=0 PL:DP:DV 0,39,203:13:0 0,15,127:5:0 0,18,180:6:0 +17 3761 . A 0 . DP=24;I16=17,7,0,0,871,32185,0,0,1218,66404,0,0,460,10624,0,0;QS=3,0;MQSB=0.95083;MQ0F=0 PL:DP:DV 0,39,215:13:0 0,15,136:5:0 0,18,188:6:0 +17 3762 . C 0 . DP=25;I16=17,7,0,0,831,29665,0,0,1241,68635,0,0,435,9983,0,0;QS=3,0;MQSB=0.69242;MQ0F=0 PL:DP:DV 0,39,209:13:0 0,18,149:6:0 0,15,159:5:0 +17 3763 . C 0 . DP=24;I16=16,8,0,0,837,30619,0,0,1218,66404,0,0,460,10510,0,0;QS=3,0;MQSB=0.844324;MQ0F=0 PL:DP:DV 0,36,213:12:0 0,18,149:6:0 0,18,186:6:0 +17 3764 . A 0 . DP=25;I16=17,7,0,0,856,31506,0,0,1241,68635,0,0,437,9903,0,0;QS=3,0;MQSB=0.69242;MQ0F=0 PL:DP:DV 0,39,212:13:0 0,18,139:6:0 0,15,167:5:0 +17 3765 . C 0 . DP=25;I16=17,7,0,0,845,31099,0,0,1218,66404,0,0,436,9750,0,0;QS=3,0;MQSB=0.95083;MQ0F=0 PL:DP:DV 0,39,200:13:0 0,15,129:5:0 0,18,189:6:0 +17 3766 . A 0 . DP=26;I16=17,9,0,0,953,35331,0,0,1338,73604,0,0,462,10340,0,0;QS=3,0;MQSB=0.811273;MQ0F=0 PL:DP:DV 0,42,248:14:0 0,18,158:6:0 0,18,191:6:0 +17 3767 . A 0 . DP=26;I16=17,9,0,0,924,33656,0,0,1338,73604,0,0,464,10328,0,0;QS=3,0;MQSB=0.811273;MQ0F=0 PL:DP:DV 0,42,246:14:0 0,18,148:6:0 0,18,191:6:0 +17 3768 . A 0 . DP=26;I16=17,9,0,0,922,33842,0,0,1338,73604,0,0,466,10340,0,0;QS=3,0;MQSB=0.811273;MQ0F=0 PL:DP:DV 0,42,237:14:0 0,18,146:6:0 0,18,195:6:0 +17 3769 . T 0 . DP=26;I16=17,8,0,0,891,32735,0,0,1278,70004,0,0,461,10327,0,0;QS=3,0;MQSB=0.884621;MQ0F=0 PL:DP:DV 0,42,246:14:0 0,15,144:5:0 0,18,191:6:0 +17 3770 . C 0 . DP=26;I16=17,9,0,0,923,34049,0,0,1338,73604,0,0,470,10436,0,0;QS=3,0;MQSB=0.811273;MQ0F=0 PL:DP:DV 0,42,252:14:0 0,18,142:6:0 0,18,180:6:0 +17 3771 . T 0 . DP=25;I16=16,8,0,0,852,31694,0,0,1218,66404,0,0,464,10438,0,0;QS=3,0;MQSB=0.844324;MQ0F=0 PL:DP:DV 0,42,253:14:0 0,15,140:5:0 0,15,157:5:0 +17 3772 . A 0 . DP=26;I16=16,10,0,0,836,28434,0,0,1338,73604,0,0,476,10624,0,0;QS=3,0;MQSB=0.685145;MQ0F=0 PL:DP:DV 0,42,236:14:0 0,18,122:6:0 0,18,160:6:0 +17 3773 . C 0 . DP=26;I16=16,10,0,0,893,31801,0,0,1338,73604,0,0,480,10752,0,0;QS=3,0;MQSB=0.685145;MQ0F=0 PL:DP:DV 0,42,253:14:0 0,18,140:6:0 0,18,171:6:0 +17 3774 . T 0 . DP=25;I16=15,10,0,0,895,33455,0,0,1278,70004,0,0,485,10903,0,0;QS=3,0;MQSB=0.624282;MQ0F=0 PL:DP:DV 0,42,253:14:0 0,18,129:6:0 0,15,178:5:0 +17 3775 . C 0 . DP=25;I16=15,9,0,0,855,31825,0,0,1241,68635,0,0,477,10883,0,0;QS=3,0;MQSB=0.439649;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,147:6:0 0,12,143:4:0 +17 3776 . T 0 . DP=24;I16=15,7,0,0,838,32738,0,0,1152,64194,0,0,457,10375,0,0;QS=3,0;MQSB=0.225079;MQ0F=0 PL:DP:DV 0,39,229:13:0 0,15,149:5:0 0,12,152:4:0 +17 3777 . C 0 . DP=24;I16=15,9,0,0,864,32180,0,0,1218,66404,0,0,492,10998,0,0;QS=3,0;MQSB=0.705785;MQ0F=0 PL:DP:DV 0,39,220:13:0 0,18,160:6:0 0,15,168:5:0 +17 3778 . T 0 . DP=24;I16=14,9,0,0,859,32957,0,0,1208,66304,0,0,468,10372,0,0;QS=3,0;MQSB=0.836049;MQ0F=0 PL:DP:DV 0,36,227:12:0 0,18,157:6:0 0,15,167:5:0 +17 3779 . G 0 . DP=24;I16=15,9,0,0,844,31206,0,0,1218,66404,0,0,493,10971,0,0;QS=3,0;MQSB=0.705785;MQ0F=0 PL:DP:DV 0,39,220:13:0 0,18,152:6:0 0,15,167:5:0 +17 3780 . C 0 . DP=25;I16=14,10,0,0,829,29949,0,0,1268,69904,0,0,467,10295,0,0;QS=3,0;MQSB=0.765017;MQ0F=0 PL:DP:DV 0,39,235:13:0 0,18,144:6:0 0,15,169:5:0 +17 3781 . C 0 . DP=26;I16=16,10,0,0,939,34725,0,0,1315,71373,0,0,492,10896,0,0;QS=3,0;MQSB=0.541994;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,139:6:0 0,15,175:5:0 +17 3782 . T 0 . DP=26;I16=16,10,0,0,989,38031,0,0,1315,71373,0,0,493,10901,0,0;QS=3,0;MQSB=0.541994;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,169:6:0 0,15,176:5:0 +17 3783 . C 0 . DP=26;I16=16,10,0,0,941,34801,0,0,1315,71373,0,0,492,10836,0,0;QS=3,0;MQSB=0.541994;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,155:6:0 0,15,162:5:0 +17 3784 . T 0 . DP=27;I16=16,11,0,0,1001,38035,0,0,1375,74973,0,0,491,10801,0,0;QS=3,0;MQSB=0.467219;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,155:6:0 0,15,178:5:0 +17 3785 . G 0 . DP=28;I16=15,10,0,0,922,36426,0,0,1305,71273,0,0,450,9916,0,0;QS=3,0;MQSB=0.674458;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,125:5:0 0,15,179:5:0 +17 3786 . T 0 . DP=28;I16=16,11,0,0,935,35697,0,0,1375,74973,0,0,490,10774,0,0;QS=3,0;MQSB=0.467219;MQ0F=0 PL:DP:DV 0,48,250:16:0 0,18,145:6:0 0,15,186:5:0 +17 3787 . G 0 . DP=28;I16=16,11,0,0,963,37951,0,0,1375,74973,0,0,489,10781,0,0;QS=3,0;MQSB=0.467219;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,143:6:0 0,15,177:5:0 +17 3788 . G 0 . DP=26;I16=14,9,0,0,849,33683,0,0,1184,65386,0,0,459,10075,0,0;QS=3,0;MQSB=0.525788;MQ0F=0 PL:DP:DV 0,39,239:13:0 0,18,144:6:0 0,12,161:4:0 +17 3789 . G 0 . DP=26;I16=13,10,0,0,807,31019,0,0,1231,68535,0,0,438,9474,0,0;QS=3,0;MQSB=0.445672;MQ0F=0 PL:DP:DV 0,39,251:13:0 0,18,133:6:0 0,12,161:4:0 +17 3790 . T 0 . DP=26;I16=13,10,0,0,829,32293,0,0,1231,68535,0,0,435,9359,0,0;QS=3,0;MQSB=0.445672;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,150:6:0 0,12,159:4:0 +17 3791 . T 0 . DP=26;I16=15,10,0,0,887,34725,0,0,1301,72235,0,0,478,10336,0,0;QS=3,0;MQSB=0.382304;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,136:6:0 0,12,159:4:0 +17 3792 . G A, 0 . DP=26;I16=14,8,1,0,809,32805,38,1444,1175,66425,37,1369,417,8991,22,484;QS=2.92629,0.0737052,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.195278;BQB=1;MQ0F=0 PL:DP:DV 0,8,238,42,241,255:15:1 0,12,109,12,109,109:4:0 0,12,157,12,157,157:4:0 +17 3793 . A 0 . DP=26;I16=15,8,0,0,833,33775,0,0,1212,67794,0,0,435,9363,0,0;QS=3,0;MQSB=0.195278;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,93:4:0 0,12,159:4:0 +17 3794 . C 0 . DP=26;I16=15,9,0,0,845,33023,0,0,1241,68635,0,0,438,9324,0,0;QS=3,0;MQSB=0.439649;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,120:5:0 0,12,157:4:0 +17 3795 . C 0 . DP=26;I16=14,9,0,0,865,35649,0,0,1231,68535,0,0,408,8622,0,0;QS=3,0;MQSB=0.563599;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,132:5:0 0,12,161:4:0 +17 3796 . T 0 . DP=27;I16=15,11,0,0,964,38998,0,0,1361,75835,0,0,453,9821,0,0;QS=3,0;MQSB=0.334895;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,149:7:0 0,12,164:4:0 +17 3797 . A 0 . DP=27;I16=15,10,0,0,848,32392,0,0,1301,72235,0,0,424,9172,0,0;QS=3,0;MQSB=0.382304;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,124:6:0 0,12,159:4:0 +17 3798 . T 0 . DP=27;I16=14,11,0,0,921,37161,0,0,1301,72235,0,0,430,9554,0,0;QS=3,0;MQSB=0.283586;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,148:7:0 0,12,165:4:0 +17 3799 . T 0 . DP=27;I16=15,11,0,0,913,35929,0,0,1361,75835,0,0,439,9729,0,0;QS=3,0;MQSB=0.334895;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,150:7:0 0,12,161:4:0 +17 3800 . C 0 . DP=26;I16=13,10,0,0,866,36182,0,0,1181,65035,0,0,406,9092,0,0;QS=3,0;MQSB=0.272532;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,104:5:0 0,12,161:4:0 +17 3801 . T 0 . DP=23;I16=12,10,0,0,804,33600,0,0,1121,61435,0,0,430,9750,0,0;QS=3,0;MQSB=0.217267;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,99:5:0 0,9,133:3:0 +17 3802 . G 0 . DP=22;I16=10,9,0,0,730,30516,0,0,994,54486,0,0,380,8550,0,0;QS=3,0;MQSB=0.472367;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,106:4:0 0,9,130:3:0 +17 3803 . G 0 . DP=22;I16=11,9,0,0,703,27393,0,0,1051,57735,0,0,405,9241,0,0;QS=3,0;MQSB=0.372419;MQ0F=0 PL:DP:DV 0,39,249:13:0 0,12,92:4:0 0,9,129:3:0 +17 3804 . A 0 . DP=22;I16=11,9,0,0,740,30360,0,0,1051,57735,0,0,404,9274,0,0;QS=3,0;MQSB=0.372419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,98:4:0 0,9,132:3:0 +17 3805 . C 0 . DP=22;I16=12,9,0,0,737,29243,0,0,1061,57835,0,0,428,9950,0,0;QS=3,0;MQSB=0.262932;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,81:4:0 0,9,130:3:0 +17 3806 . A 0 . DP=22;I16=12,9,0,0,798,32550,0,0,1061,57835,0,0,426,9968,0,0;QS=3,0;MQSB=0.262932;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,105:4:0 0,9,128:3:0 +17 3807 . C 0 . DP=22;I16=10,9,0,0,664,25304,0,0,994,54486,0,0,377,8885,0,0;QS=3,0;MQSB=0.472367;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,83:4:0 0,9,115:3:0 +17 3808 . G 0 . DP=21;I16=9,9,0,0,653,25297,0,0,957,53117,0,0,375,8873,0,0;QS=3,0;MQSB=0.597145;MQ0F=0 PL:DP:DV 0,33,233:11:0 0,12,109:4:0 0,9,132:3:0 +17 3809 . T 0 . DP=22;I16=11,10,0,0,779,32151,0,0,1084,60066,0,0,416,9810,0,0;QS=3,0;MQSB=0.285029;MQ0F=0 PL:DP:DV 0,39,249:13:0 0,12,115:4:0 0,12,161:4:0 +17 3810 . C 0 . DP=23;I16=9,11,0,0,811,34815,0,0,1077,60317,0,0,369,8739,0,0;QS=3,0;MQSB=0.499893;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,112:4:0 0,12,153:4:0 +17 3811 . A C, 0 . DP=23;I16=9,11,2,0,777,32631,39,785,1077,60317,67,3349,367,8669,42,914;QS=2.94104,0.0589569,0;VDB=0.18;SGB=0.346553;RPB=0.425;MQB=0.25;MQSB=0.246128;BQB=0.025;MQ0F=0 PL:DP:DV 0,15,248,36,254,255:14:2 0,12,116,12,116,116:4:0 0,12,158,12,158,158:4:0 +17 3812 . T 0 . DP=23;I16=10,11,0,0,802,32860,0,0,1084,60066,0,0,405,9447,0,0;QS=3,0;MQSB=0.187115;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,114:4:0 0,12,160:4:0 +17 3813 . A 0 . DP=22;I16=10,11,0,0,815,35077,0,0,1084,60066,0,0,402,9330,0,0;QS=3,0;MQSB=0.187115;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,119:4:0 0,12,170:4:0 +17 3814 . G 0 . DP=21;I16=8,11,0,0,775,33731,0,0,1037,58597,0,0,375,8605,0,0;QS=3,0;MQSB=0.41781;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,113:4:0 0,12,163:4:0 +17 3815 . A 0 . DP=20;I16=8,11,0,0,708,29130,0,0,1010,57328,0,0,397,9049,0,0;QS=3,0;MQSB=0.373354;MQ0F=0 PL:DP:DV 0,33,239:11:0 0,12,110:4:0 0,12,162:4:0 +17 3816 . A 0 . DP=20;I16=8,11,0,0,729,31027,0,0,1010,57328,0,0,395,8933,0,0;QS=3,0;MQSB=0.373354;MQ0F=0 PL:DP:DV 0,33,248:11:0 0,12,104:4:0 0,12,160:4:0 +17 3817 . A 0 . DP=20;I16=8,11,0,0,752,31580,0,0,1010,57328,0,0,393,8833,0,0;QS=3,0;MQSB=0.373354;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,110:4:0 0,12,161:4:0 +17 3818 . T 0 . DP=20;I16=8,11,0,0,728,30466,0,0,1010,57328,0,0,391,8749,0,0;QS=3,0;MQSB=0.373354;MQ0F=0 PL:DP:DV 0,33,252:11:0 0,12,115:4:0 0,12,160:4:0 +17 3819 . A 0 . DP=21;I16=9,11,0,0,790,34094,0,0,1039,58169,0,0,389,8681,0,0;QS=3,0;MQSB=0.247381;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,121:4:0 0,12,167:4:0 +17 3820 . G 0 . DP=21;I16=9,11,0,0,788,33636,0,0,1039,58169,0,0,388,8630,0,0;QS=3,0;MQSB=0.247381;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,112:4:0 0,12,157:4:0 +17 3821 . A 0 . DP=22;I16=10,11,0,0,832,35864,0,0,1099,61769,0,0,387,8597,0,0;QS=3,0;MQSB=0.317882;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,115:4:0 0,12,168:4:0 +17 3822 . G 0 . DP=22;I16=10,11,0,0,810,33228,0,0,1099,61769,0,0,386,8532,0,0;QS=3,0;MQSB=0.317882;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,103:4:0 0,12,157:4:0 +17 3823 . T 0 . DP=22;I16=9,11,0,0,753,30705,0,0,1042,58520,0,0,380,8460,0,0;QS=3,0;MQSB=0.434285;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,102:4:0 0,12,163:4:0 +17 3824 . C 0 . DP=22;I16=10,11,0,0,802,32368,0,0,1099,61769,0,0,384,8456,0,0;QS=3,0;MQSB=0.317882;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,105:4:0 0,12,159:4:0 +17 3825 . C 0 . DP=23;I16=10,11,0,0,813,33955,0,0,1079,59889,0,0,379,8387,0,0;QS=3,0;MQSB=0.317882;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,130:5:0 0,12,157:4:0 +17 3826 . T 0 . DP=23;I16=11,11,0,0,827,34611,0,0,1136,63138,0,0,381,8357,0,0;QS=3,0;MQSB=0.232836;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,133:5:0 0,12,155:4:0 +17 3827 . G 0 . DP=23;I16=11,10,0,0,820,34130,0,0,1076,59538,0,0,355,7715,0,0;QS=3,0;MQSB=0.269397;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,121:4:0 0,12,162:4:0 +17 3828 . C 0 . DP=23;I16=11,10,0,0,805,33147,0,0,1076,59538,0,0,354,7720,0,0;QS=3,0;MQSB=0.269397;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,114:4:0 0,12,157:4:0 +17 3829 . A 0 . DP=22;I16=9,11,0,0,763,31295,0,0,1069,59789,0,0,369,8241,0,0;QS=3,0;MQSB=0.477679;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,132:5:0 0,12,158:4:0 +17 3830 . A 0 . DP=23;I16=11,11,0,0,825,32693,0,0,1136,63138,0,0,377,8321,0,0;QS=3,0;MQSB=0.232836;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,143:5:0 0,12,150:4:0 +17 3831 . C A, 0 . DP=23;I16=10,11,1,0,802,32198,14,196,1126,63038,10,100,370,8294,7,49;QS=2.97758,0.0224215,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.232836;BQB=1;MQ0F=0 PL:DP:DV 0,27,255,36,255,255:13:1 0,15,134,15,134,134:5:0 0,12,149,12,149,149:4:0 +17 3832 . A 0 . DP=24;I16=12,11,0,0,836,32436,0,0,1196,66738,0,0,377,8389,0,0;QS=3,0;MQSB=0.291845;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,136:5:0 0,12,139:4:0 +17 3833 . C 0 . DP=23;I16=10,11,0,0,690,24938,0,0,1076,59538,0,0,377,8409,0,0;QS=3,0;MQSB=0.175325;MQ0F=0 PL:DP:DV 0,36,249:12:0 0,15,113:5:0 0,12,131:4:0 +17 3834 . G 0 . DP=22;I16=9,10,0,0,684,26250,0,0,1037,58597,0,0,357,8079,0,0;QS=3,0;MQSB=0.124514;MQ0F=0 PL:DP:DV 0,33,242:11:0 0,12,122:4:0 0,12,156:4:0 +17 3835 . T 0 . DP=22;I16=10,11,0,0,773,30373,0,0,1076,59538,0,0,381,8475,0,0;QS=3,0;MQSB=0.175325;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,140:5:0 0,12,153:4:0 +17 3836 . G C, 0 . DP=24;I16=10,12,1,0,833,33183,14,196,1132,61648,10,100,378,8412,2,4;QS=2.97647,0.0235294,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.251407;BQB=1;MQ0F=0 PL:DP:DV 0,27,255,36,255,255:13:1 0,15,149,15,149,149:5:0 0,15,188,15,188,188:5:0 +17 3837 . G 0 . DP=24;I16=8,14,0,0,759,26931,0,0,1135,61999,0,0,399,8955,0,0;QS=3,0;MQSB=0.291667;MQ0F=0 PL:DP:DV 0,33,245:11:0 0,18,149:6:0 0,15,157:5:0 +17 3838 . C 0 . DP=24;I16=10,14,0,0,817,28975,0,0,1202,65348,0,0,409,8945,0,0;QS=3,0;MQSB=0.122456;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,143:6:0 0,15,148:5:0 +17 3839 . C 0 . DP=23;I16=9,13,0,0,688,22248,0,0,1132,61648,0,0,386,8238,0,0;QS=3,0;MQSB=0.248197;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,123:6:0 0,12,112:4:0 +17 3840 . G 0 . DP=23;I16=9,14,0,0,793,27941,0,0,1192,65248,0,0,413,8809,0,0;QS=3,0;MQSB=0.211072;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,160:6:0 0,15,146:5:0 +17 3841 . T 0 . DP=23;I16=9,14,0,0,867,33103,0,0,1192,65248,0,0,414,8734,0,0;QS=3,0;MQSB=0.211072;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,167:6:0 0,15,162:5:0 +17 3842 . C 0 . DP=23;I16=9,14,0,0,890,34728,0,0,1192,65248,0,0,415,8689,0,0;QS=3,0;MQSB=0.211072;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,167:6:0 0,15,159:5:0 +17 3843 . T 0 . DP=24;I16=9,14,0,0,896,35122,0,0,1192,65248,0,0,416,8674,0,0;QS=3,0;MQSB=0.211072;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,164:6:0 0,15,159:5:0 +17 3844 . G 0 . DP=26;I16=10,16,0,0,959,35715,0,0,1372,76048,0,0,442,9314,0,0;QS=3,0;MQSB=0.220358;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,177:7:0 0,18,172:6:0 +17 3845 . T 0 . DP=26;I16=10,16,0,0,970,36442,0,0,1372,76048,0,0,444,9310,0,0;QS=3,0;MQSB=0.220358;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,186:7:0 0,18,166:6:0 +17 3846 . G 0 . DP=27;I16=10,17,0,0,993,37297,0,0,1432,79648,0,0,446,9338,0,0;QS=3,0;MQSB=0.195223;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,175:7:0 0,21,172:7:0 +17 3847 . T 0 . DP=27;I16=10,16,0,0,952,35268,0,0,1372,76048,0,0,423,8723,0,0;QS=3,0;MQSB=0.220358;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,170:6:0 0,21,189:7:0 +17 3848 . C 0 . DP=27;I16=10,17,0,0,1025,39533,0,0,1432,79648,0,0,449,9341,0,0;QS=3,0;MQSB=0.195223;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,177:7:0 0,21,188:7:0 +17 3849 . T 0 . DP=27;I16=9,17,0,0,987,37685,0,0,1395,78279,0,0,450,9368,0,0;QS=3,0;MQSB=0.282527;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,179:7:0 0,21,190:7:0 +17 3850 . G 0 . DP=26;I16=9,17,0,0,957,35751,0,0,1395,78279,0,0,452,9428,0,0;QS=3,0;MQSB=0.282527;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,179:7:0 0,21,182:7:0 +17 3851 . G 0 . DP=26;I16=9,17,0,0,965,36475,0,0,1395,78279,0,0,453,9469,0,0;QS=3,0;MQSB=0.282527;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,177:7:0 0,21,183:7:0 +17 3852 . C 0 . DP=26;I16=9,16,0,0,921,34525,0,0,1335,74679,0,0,444,9440,0,0;QS=3,0;MQSB=0.310905;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,163:6:0 0,21,179:7:0 +17 3853 . T 0 . DP=28;I16=10,18,0,0,1050,40222,0,0,1484,82720,0,0,455,9641,0,0;QS=3,0;MQSB=0.515783;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,185:7:0 0,21,192:7:0 +17 3854 . T 0 . DP=28;I16=10,17,0,0,955,34605,0,0,1455,81879,0,0,451,9709,0,0;QS=3,0;MQSB=0.359211;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,171:6:0 0,18,178:6:0 +17 3855 . C 0 . DP=29;I16=10,18,0,0,992,36040,0,0,1515,85479,0,0,438,9264,0,0;QS=3,0;MQSB=0.331344;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,139:5:0 0,21,175:7:0 +17 3856 . T 0 . DP=30;I16=10,18,0,0,1033,38725,0,0,1546,88238,0,0,464,9982,0,0;QS=3,0;MQSB=0.190183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,163:6:0 0,21,185:7:0 +17 3857 . C 0 . DP=30;I16=10,19,0,0,1077,40979,0,0,1575,89079,0,0,447,9505,0,0;QS=3,0;MQSB=0.306875;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,154:5:0 0,24,194:8:0 +17 3858 . T 0 . DP=31;I16=10,21,0,0,1141,42567,0,0,1695,96279,0,0,477,10255,0,0;QS=3,0;MQSB=0.266219;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,171:6:0 0,24,208:8:0 +17 3859 . C 0 . DP=32;I16=10,21,0,0,950,30078,0,0,1695,96279,0,0,484,10416,0,0;QS=3,0;MQSB=0.266219;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,136:6:0 0,24,156:8:0 +17 3860 . G 0 . DP=32;I16=10,22,0,0,1070,37794,0,0,1755,99879,0,0,516,11240,0,0;QS=3,0;MQSB=0.249261;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,154:6:0 0,27,209:9:0 +17 3861 . C 0 . DP=33;I16=11,20,0,0,1133,42547,0,0,1672,94048,0,0,517,11391,0,0;QS=3,0;MQSB=0.19205;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,162:6:0 0,24,199:8:0 +17 3862 . T 0 . DP=34;I16=11,22,0,0,1241,47443,0,0,1792,101248,0,0,526,11518,0,0;QS=3,0;MQSB=0.161533;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,185:7:0 0,27,221:9:0 +17 3863 . T 0 . DP=34;I16=12,22,0,0,1200,43542,0,0,1852,104848,0,0,541,11685,0,0;QS=3,0;MQSB=0.210327;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,199:7:0 0,27,213:9:0 +17 3864 . A 0 . DP=33;I16=11,22,0,0,1238,47448,0,0,1792,101248,0,0,550,11790,0,0;QS=3,0;MQSB=0.161533;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,210:7:0 0,27,230:9:0 +17 3865 . G 0 . DP=34;I16=11,23,0,0,1251,47113,0,0,1852,104848,0,0,559,11933,0,0;QS=3,0;MQSB=0.149071;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,200:7:0 0,27,212:9:0 +17 3866 . C 0 . DP=33;I16=11,21,0,0,1165,43545,0,0,1732,97648,0,0,545,11489,0,0;QS=3,0;MQSB=0.175751;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,189:7:0 0,24,197:8:0 +17 3867 . A 0 . DP=33;I16=11,22,0,0,1152,41510,0,0,1792,101248,0,0,580,12284,0,0;QS=3,0;MQSB=0.161533;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,188:7:0 0,27,195:9:0 +17 3868 . T 0 . DP=33;I16=11,22,0,0,1255,48141,0,0,1792,101248,0,0,590,12494,0,0;QS=3,0;MQSB=0.161533;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,202:7:0 0,27,221:9:0 +17 3869 . C 0 . DP=33;I16=11,21,0,0,1169,43987,0,0,1732,97648,0,0,589,12623,0,0;QS=3,0;MQSB=0.175751;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,164:6:0 0,27,211:9:0 +17 3870 . T 0 . DP=34;I16=11,23,0,0,1262,47808,0,0,1852,104848,0,0,608,12932,0,0;QS=3,0;MQSB=0.149071;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,215:8:0 0,27,211:9:0 +17 3871 . T 0 . DP=36;I16=11,25,0,0,1341,50655,0,0,1972,112048,0,0,617,13157,0,0;QS=3,0;MQSB=0.128391;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,221:8:0 0,27,223:9:0 +17 3872 . G 0 . DP=36;I16=11,25,0,0,1287,47095,0,0,1972,112048,0,0,626,13322,0,0;QS=3,0;MQSB=0.128391;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,211:8:0 0,27,200:9:0 +17 3873 . T 0 . DP=35;I16=10,24,0,0,1242,46680,0,0,1852,104848,0,0,626,13428,0,0;QS=3,0;MQSB=0.0982034;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,194:7:0 0,24,212:8:0 +17 3874 . T 0 . DP=36;I16=12,24,0,0,1290,47660,0,0,1972,112048,0,0,646,13774,0,0;QS=3,0;MQSB=0.182088;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,24,228:8:0 0,24,204:8:0 +17 3875 . T 0 . DP=37;I16=13,24,0,0,1324,48418,0,0,2029,115297,0,0,657,14061,0,0;QS=3,0;MQSB=0.117872;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,231:8:0 0,24,197:8:0 +17 3876 . C 0 . DP=37;I16=13,22,0,0,1248,45354,0,0,1909,108097,0,0,623,13325,0,0;QS=3,0;MQSB=0.140806;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,196:7:0 0,24,180:8:0 +17 3877 . C 0 . DP=37;I16=13,24,0,0,1363,51201,0,0,2029,115297,0,0,681,14765,0,0;QS=3,0;MQSB=0.117872;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,217:8:0 0,24,196:8:0 +17 3878 . A 0 . DP=37;I16=13,23,0,0,1309,48045,0,0,1969,111697,0,0,670,14654,0,0;QS=3,0;MQSB=0.128568;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,24,218:8:0 0,24,188:8:0 +17 3879 . A 0 . DP=38;I16=14,24,0,0,1453,56567,0,0,2066,116666,0,0,703,15543,0,0;QS=3,0;MQSB=0.076112;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,226:8:0 0,24,206:8:0 +17 3880 . G 0 . DP=37;I16=14,22,0,0,1311,48735,0,0,1946,109466,0,0,689,15267,0,0;QS=3,0;MQSB=0.094094;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,24,209:8:0 0,24,183:8:0 +17 3881 . G 0 . DP=37;I16=14,21,0,0,1200,42778,0,0,1886,105866,0,0,690,15578,0,0;QS=3,0;MQSB=0.105399;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,18,178:6:0 0,24,174:8:0 +17 3882 . T 0 . DP=37;I16=14,21,0,0,1192,42352,0,0,1886,105866,0,0,684,15348,0,0;QS=3,0;MQSB=0.105399;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,21,189:7:0 0,21,178:7:0 +17 3883 . C 0 . DP=38;I16=15,22,0,0,1295,46659,0,0,2006,113066,0,0,717,16279,0,0;QS=3,0;MQSB=0.124405;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,205:8:0 0,24,171:8:0 +17 3884 . C 0 . DP=39;I16=16,23,0,0,1363,49387,0,0,2103,118035,0,0,749,17141,0,0;QS=3,0;MQSB=0.0760633;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,202:8:0 0,27,212:9:0 +17 3885 . T 0 . DP=40;I16=16,24,0,0,1445,53663,0,0,2163,121635,0,0,754,17262,0,0;QS=3,0;MQSB=0.0679472;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,24,219:8:0 0,27,214:9:0 +17 3886 . C 0 . DP=39;I16=16,23,0,0,1370,49762,0,0,2103,118035,0,0,761,17421,0,0;QS=3,0;MQSB=0.0760633;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,24,199:8:0 0,24,191:8:0 +17 3887 . C 0 . DP=39;I16=16,23,0,0,1364,49222,0,0,2103,118035,0,0,767,17567,0,0;QS=3,0;MQSB=0.0760633;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,24,194:8:0 0,24,201:8:0 +17 3888 . C 0 . DP=39;I16=15,23,0,0,1387,51885,0,0,2043,114435,0,0,747,17073,0,0;QS=3,0;MQSB=0.0555905;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,195:8:0 0,24,208:8:0 +17 3889 . A 0 . DP=38;I16=15,23,0,0,1364,49918,0,0,2066,116666,0,0,777,17811,0,0;QS=3,0;MQSB=0.112471;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,202:8:0 0,24,218:8:0 +17 3890 . C 0 . DP=38;I16=14,23,0,0,1362,51064,0,0,2006,113066,0,0,757,17329,0,0;QS=3,0;MQSB=0.0844255;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,203:8:0 0,24,216:8:0 +17 3891 . A 0 . DP=39;I16=15,24,0,0,1466,56312,0,0,2126,120266,0,0,786,18076,0,0;QS=3,0;MQSB=0.102114;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,203:8:0 0,27,239:9:0 +17 3892 . G 0 . DP=38;I16=15,23,0,0,1340,48838,0,0,2066,116666,0,0,792,18226,0,0;QS=3,0;MQSB=0.112471;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,186:8:0 0,27,208:9:0 +17 3893 . T 0 . DP=39;I16=15,24,0,0,1348,48170,0,0,2126,120266,0,0,798,18404,0,0;QS=3,0;MQSB=0.102114;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,196:8:0 0,27,212:9:0 +17 3894 . G 0 . DP=39;I16=15,23,0,0,1364,49900,0,0,2066,116666,0,0,779,17937,0,0;QS=3,0;MQSB=0.112471;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,202:8:0 0,27,208:9:0 +17 3895 . T 0 . DP=39;I16=15,24,0,0,1375,49773,0,0,2126,120266,0,0,810,18752,0,0;QS=3,0;MQSB=0.102114;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,202:8:0 0,27,225:9:0 +17 3896 . A 0 . DP=40;I16=15,24,0,0,1468,57326,0,0,2126,120266,0,0,815,18923,0,0;QS=3,0;MQSB=0.102114;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,224:8:0 0,27,233:9:0 +17 3897 . G 0 . DP=40;I16=15,24,0,0,1468,56812,0,0,2126,120266,0,0,819,19021,0,0;QS=3,0;MQSB=0.102114;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,21,199:7:0 0,30,234:10:0 +17 3898 . C 0 . DP=40;I16=15,23,0,0,1487,59351,0,0,2066,116666,0,0,813,19023,0,0;QS=3,0;MQSB=0.112471;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,18,186:6:0 0,30,238:10:0 +17 3899 . A 0 . DP=40;I16=15,24,0,0,1449,55055,0,0,2126,120266,0,0,829,19293,0,0;QS=3,0;MQSB=0.102114;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,21,191:7:0 0,30,231:10:0 +17 3900 . T 0 . DP=40;I16=15,24,0,0,1458,55516,0,0,2126,120266,0,0,833,19417,0,0;QS=3,0;MQSB=0.102114;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,21,197:7:0 0,30,240:10:0 +17 3901 . G 0 . DP=40;I16=14,22,0,0,1303,48245,0,0,1969,111697,0,0,761,17639,0,0;QS=3,0;MQSB=0.180757;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,18,154:6:0 0,27,218:9:0 +17 3902 . C 0 . DP=40;I16=15,24,0,0,1436,55412,0,0,2126,120266,0,0,837,19537,0,0;QS=3,0;MQSB=0.102114;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,21,166:7:0 0,30,217:10:0 +17 3903 . A 0 . DP=42;I16=15,24,0,0,1299,45567,0,0,2089,117417,0,0,814,19008,0,0;QS=3,0;MQSB=0.0901152;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,175:8:0 0,30,204:10:0 +17 3904 . C 0 . DP=42;I16=15,24,0,0,1439,54545,0,0,2086,117066,0,0,815,19113,0,0;QS=3,0;MQSB=0.0426917;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,191:8:0 0,30,244:10:0 +17 3905 . C 0 . DP=42;I16=15,25,0,0,1572,63314,0,0,2146,120666,0,0,822,19192,0,0;QS=3,0;MQSB=0.0381122;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,212:8:0 0,33,255:11:0 +17 3906 . T 0 . DP=42;I16=16,25,0,0,1593,63039,0,0,2206,124266,0,0,846,19758,0,0;QS=3,0;MQSB=0.0536599;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,210:8:0 0,33,253:11:0 +17 3907 . G 0 . DP=42;I16=16,25,0,0,1558,60192,0,0,2206,124266,0,0,846,19776,0,0;QS=3,0;MQSB=0.0536599;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,203:8:0 0,33,249:11:0 +17 3908 . C 0 . DP=42;I16=16,25,0,0,1514,58968,0,0,2206,124266,0,0,845,19777,0,0;QS=3,0;MQSB=0.0536599;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,193:8:0 0,33,244:11:0 +17 3909 . T 0 . DP=43;I16=16,25,0,0,1491,55895,0,0,2201,123691,0,0,835,19697,0,0;QS=3,0;MQSB=0.0757469;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,24,202:8:0 0,30,237:10:0 +17 3910 . A 0 . DP=40;I16=16,23,0,0,1432,53926,0,0,2081,116491,0,0,844,19724,0,0;QS=3,0;MQSB=0.0949554;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,21,193:7:0 0,30,224:10:0 +17 3911 . C 0 . DP=40;I16=16,23,0,0,1440,55290,0,0,2081,116491,0,0,843,19613,0,0;QS=3,0;MQSB=0.0949554;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,21,184:7:0 0,30,214:10:0 +17 3912 . A C, 0 . DP=41;I16=17,22,0,1,1358,49508,16,256,2081,116491,60,3600,830,19358,11,121;QS=2.95181,0.0481928,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.125266;BQB=1;MQ0F=0 PL:DP:DV 0,69,255,69,255,255:23:0 0,21,166,21,166,166:7:0 0,14,202,27,205,208:10:1 +17 3913 . C 0 . DP=40;I16=16,23,0,0,1494,59096,0,0,2081,116491,0,0,824,19100,0,0;QS=3,0;MQSB=0.0949554;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,21,183:7:0 0,30,234:10:0 +17 3914 . T 0 . DP=42;I16=16,24,0,0,1512,59342,0,0,2141,120091,0,0,823,19007,0,0;QS=3,0;MQSB=0.0846181;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,21,192:7:0 0,30,228:10:0 +17 3915 . C 0 . DP=42;I16=16,24,0,0,1537,60953,0,0,2141,120091,0,0,799,18321,0,0;QS=3,0;MQSB=0.0846181;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,18,176:6:0 0,30,229:10:0 +17 3916 . C 0 . DP=42;I16=16,25,0,0,1618,66342,0,0,2201,123691,0,0,825,18919,0,0;QS=3,0;MQSB=0.0757469;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,21,190:7:0 0,30,251:10:0 +17 3917 . T 0 . DP=43;I16=16,25,0,0,1601,65219,0,0,2201,123691,0,0,825,18875,0,0;QS=3,0;MQSB=0.0757469;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,21,191:7:0 0,30,254:10:0 +17 3918 . T 0 . DP=43;I16=16,25,0,0,1541,60711,0,0,2201,123691,0,0,801,18239,0,0;QS=3,0;MQSB=0.0757469;MQ0F=0 PL:DP:DV 0,75,255:25:0 0,18,179:6:0 0,30,254:10:0 +17 3919 . C 0 . DP=42;I16=15,26,0,0,1621,66337,0,0,2232,126450,0,0,826,18786,0,0;QS=3,0;MQSB=0.110793;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,21,200:7:0 0,30,242:10:0 +17 3920 . T 0 . DP=42;I16=15,26,0,0,1605,64327,0,0,2232,126450,0,0,825,18691,0,0;QS=3,0;MQSB=0.110793;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,21,207:7:0 0,30,251:10:0 +17 3921 . T 0 . DP=42;I16=15,26,0,0,1519,58507,0,0,2232,126450,0,0,824,18630,0,0;QS=3,0;MQSB=0.110793;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,21,201:7:0 0,30,242:10:0 +17 3922 . A 0 . DP=42;I16=14,26,0,0,1539,61289,0,0,2195,125081,0,0,819,18545,0,0;QS=3,0;MQSB=0.168991;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,18,179:6:0 0,30,244:10:0 +17 3923 . G 0 . DP=41;I16=14,25,0,0,1515,60945,0,0,2135,121481,0,0,792,17834,0,0;QS=3,0;MQSB=0.182501;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,18,172:6:0 0,30,240:10:0 +17 3924 . G 0 . DP=41;I16=13,26,0,0,1524,61106,0,0,2135,121481,0,0,808,18356,0,0;QS=3,0;MQSB=0.128469;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,18,158:6:0 0,30,247:10:0 +17 3925 . G 0 . DP=41;I16=14,25,0,0,1425,55687,0,0,2135,121481,0,0,788,17758,0,0;QS=3,0;MQSB=0.182501;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,15,134:5:0 0,30,245:10:0 +17 3926 . C 0 . DP=41;I16=14,26,0,0,1512,59674,0,0,2195,125081,0,0,811,18393,0,0;QS=3,0;MQSB=0.168991;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,18,152:6:0 0,30,237:10:0 +17 3927 . T 0 . DP=41;I16=14,26,0,0,1512,59566,0,0,2195,125081,0,0,808,18384,0,0;QS=3,0;MQSB=0.168991;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,18,160:6:0 0,30,237:10:0 +17 3928 . G 0 . DP=41;I16=14,25,0,0,1479,58495,0,0,2135,121481,0,0,779,17731,0,0;QS=3,0;MQSB=0.182501;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,18,149:6:0 0,27,233:9:0 +17 3929 . A 0 . DP=41;I16=13,26,0,0,1452,56436,0,0,2135,121481,0,0,796,18256,0,0;QS=3,0;MQSB=0.128469;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,18,161:6:0 0,30,220:10:0 +17 3930 . T 0 . DP=40;I16=13,25,0,0,1387,52929,0,0,2078,118232,0,0,767,17521,0,0;QS=3,0;MQSB=0.25797;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,15,149:5:0 0,30,224:10:0 +17 3931 . A 0 . DP=40;I16=13,25,0,0,1387,52877,0,0,2078,118232,0,0,761,17439,0,0;QS=3,0;MQSB=0.25797;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,18,166:6:0 0,27,222:9:0 +17 3932 . T 0 . DP=39;I16=12,26,0,0,1394,53644,0,0,2078,118232,0,0,780,17964,0,0;QS=3,0;MQSB=0.190372;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,18,161:6:0 0,30,231:10:0 +17 3933 . T 0 . DP=38;I16=12,24,0,0,1389,54743,0,0,1958,111032,0,0,752,17366,0,0;QS=3,0;MQSB=0.218161;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,18,166:6:0 0,24,220:8:0 +17 3934 . C 0 . DP=38;I16=12,25,0,0,1395,54915,0,0,2018,114632,0,0,768,17758,0,0;QS=3,0;MQSB=0.203497;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,18,152:6:0 0,27,209:9:0 +17 3935 . C 0 . DP=38;I16=12,24,0,0,1239,44621,0,0,1958,111032,0,0,737,17075,0,0;QS=3,0;MQSB=0.218161;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,15,134:5:0 0,27,170:9:0 +17 3936 . A G, 0 . DP=37;I16=5,6,6,17,424,16384,801,30271,609,34563,1314,77018,225,5325,511,11851;QS=0.87994,2.12006,0;VDB=0.0574114;SGB=-4.60123;RPB=0.741697;MQB=0.812605;MQSB=0.143788;BQB=0.883831;MQ0F=0 PL:DP:DV 233,0,206,255,239,255:20:11 77,0,58,83,70,141:6:4 196,24,0,196,24,196:8:8 +17 3937 . C 0 . DP=36;I16=11,24,0,0,1155,39875,0,0,1952,112422,0,0,745,17291,0,0;QS=3,0;MQSB=0.219636;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,18,143:6:0 0,24,156:8:0 +17 3938 . G 0 . DP=35;I16=11,23,0,0,1155,41761,0,0,1892,108822,0,0,737,17079,0,0;QS=3,0;MQSB=0.231054;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,15,119:5:0 0,24,176:8:0 +17 3939 . C 0 . DP=35;I16=11,22,0,0,1273,50651,0,0,1832,105222,0,0,703,16221,0,0;QS=3,0;MQSB=0.243713;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,15,135:5:0 0,21,174:7:0 +17 3940 . A 0 . DP=35;I16=11,22,0,0,1148,42754,0,0,1832,105222,0,0,691,15867,0,0;QS=3,0;MQSB=0.243713;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,15,117:5:0 0,21,163:7:0 +17 3941 . C 0 . DP=35;I16=11,22,0,0,1216,47488,0,0,1832,105222,0,0,688,15892,0,0;QS=3,0;MQSB=0.243713;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,15,133:5:0 0,21,181:7:0 +17 3942 . C 0 . DP=35;I16=11,23,0,0,1336,54166,0,0,1892,108822,0,0,690,15772,0,0;QS=3,0;MQSB=0.231054;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,15,140:5:0 0,24,195:8:0 +17 3943 . T 0 . DP=35;I16=11,23,0,0,1296,51618,0,0,1892,108822,0,0,676,15406,0,0;QS=3,0;MQSB=0.231054;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,15,142:5:0 0,24,195:8:0 +17 3944 . G 0 . DP=34;I16=10,22,0,0,1199,46445,0,0,1803,104381,0,0,654,14954,0,0;QS=3,0;MQSB=0.1117;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,149:5:0 0,24,195:8:0 +17 3945 . C 0 . DP=33;I16=10,22,0,0,1256,51226,0,0,1772,101622,0,0,649,14657,0,0;QS=3,0;MQSB=0.187579;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,142:5:0 0,21,177:7:0 +17 3946 . T 0 . DP=33;I16=10,21,0,0,1170,45884,0,0,1712,98022,0,0,609,13599,0,0;QS=3,0;MQSB=0.199344;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,144:5:0 0,18,158:6:0 +17 3947 . A 0 . DP=32;I16=10,21,0,0,1094,41048,0,0,1712,98022,0,0,620,13820,0,0;QS=3,0;MQSB=0.199344;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,128:5:0 0,18,149:6:0 +17 3948 . C 0 . DP=32;I16=10,20,0,0,1134,45104,0,0,1652,94422,0,0,596,13344,0,0;QS=3,0;MQSB=0.212591;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,105:4:0 0,18,155:6:0 +17 3949 . A C, 0 . DP=32;I16=10,17,0,1,1027,39909,24,576,1472,83622,60,3600,541,12211,25,625;QS=2.85093,0.149068,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.244621;BQB=1;MQ0F=0 PL:DP:DV 0,60,255,60,255,255:20:0 0,9,89,9,89,89:3:0 9,0,107,21,110,124:5:1 +17 3950 . C 0 . DP=33;I16=11,21,0,0,1191,46247,0,0,1772,101622,0,0,576,12680,0,0;QS=3,0;MQSB=0.257801;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,15,118:5:0 0,18,168:6:0 +17 3951 . T 0 . DP=34;I16=12,19,0,0,1148,44272,0,0,1712,98022,0,0,530,11670,0,0;QS=3,0;MQSB=0.354733;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,15,146:5:0 0,15,152:5:0 +17 3952 . C 0 . DP=35;I16=13,20,0,0,1176,43762,0,0,1832,105222,0,0,545,12025,0,0;QS=3,0;MQSB=0.394875;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,18,158:6:0 0,15,143:5:0 +17 3953 . C 0 . DP=34;I16=13,20,0,0,1246,48436,0,0,1863,107981,0,0,538,11772,0,0;QS=3,0;MQSB=0.252983;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,18,163:6:0 0,18,168:6:0 +17 3954 . T 0 . DP=33;I16=13,19,0,0,1195,45815,0,0,1803,104381,0,0,526,11438,0,0;QS=3,0;MQSB=0.264585;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,18,171:6:0 0,18,167:6:0 +17 3955 . T 0 . DP=32;I16=13,18,0,0,1180,46092,0,0,1743,100781,0,0,515,11139,0,0;QS=3,0;MQSB=0.277468;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,173:6:0 0,18,174:6:0 +17 3956 . C 0 . DP=32;I16=13,18,0,0,1181,47021,0,0,1743,100781,0,0,504,10874,0,0;QS=3,0;MQSB=0.277468;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,167:6:0 0,18,167:6:0 +17 3957 . T 0 . DP=31;I16=13,17,0,0,1153,46051,0,0,1683,97181,0,0,494,10642,0,0;QS=3,0;MQSB=0.291833;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,161:6:0 0,15,162:5:0 +17 3958 . T 0 . DP=31;I16=13,16,0,0,1070,40600,0,0,1623,93581,0,0,483,10393,0,0;QS=3,0;MQSB=0.307929;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,139:5:0 0,15,157:5:0 +17 3959 . A 0 . DP=30;I16=14,15,0,0,1062,39758,0,0,1623,93581,0,0,474,10176,0,0;QS=3,0;MQSB=0.377103;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,118:4:0 0,15,154:5:0 +17 3960 . T 0 . DP=30;I16=14,15,0,0,995,36027,0,0,1623,93581,0,0,464,9892,0,0;QS=3,0;MQSB=0.377103;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,105:4:0 0,15,142:5:0 +17 3961 . G 0 . DP=29;I16=12,16,0,0,1067,40899,0,0,1586,92212,0,0,457,9739,0,0;QS=3,0;MQSB=0.455864;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,114:4:0 0,12,122:4:0 +17 3962 . G 0 . DP=29;I16=13,16,0,0,1025,37125,0,0,1623,93581,0,0,471,10053,0,0;QS=3,0;MQSB=0.307929;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,108:4:0 0,15,144:5:0 +17 3963 . C 0 . DP=28;I16=13,15,0,0,1040,39100,0,0,1563,89981,0,0,463,9871,0,0;QS=3,0;MQSB=0.326055;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,111:4:0 0,12,126:4:0 +17 3964 . T 0 . DP=27;I16=12,15,0,0,1036,39928,0,0,1503,86381,0,0,456,9720,0,0;QS=3,0;MQSB=0.273507;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,9,94:3:0 0,12,133:4:0 +17 3965 . G 0 . DP=26;I16=12,14,0,0,993,38165,0,0,1443,82781,0,0,450,9598,0,0;QS=3,0;MQSB=0.29215;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,9,92:3:0 0,12,134:4:0 +17 3966 . A 0 . DP=26;I16=12,13,0,0,930,34834,0,0,1406,81412,0,0,432,9310,0,0;QS=3,0;MQSB=0.520812;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,90:3:0 0,12,140:4:0 +17 3967 . T 0 . DP=26;I16=12,13,0,0,900,32830,0,0,1406,81412,0,0,421,9001,0,0;QS=3,0;MQSB=0.520812;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,9,90:3:0 0,9,100:3:0 +17 3968 . A 0 . DP=25;I16=12,13,0,0,885,31773,0,0,1406,81412,0,0,415,8853,0,0;QS=3,0;MQSB=0.520812;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,9,90:3:0 0,9,99:3:0 +17 3969 . T 0 . DP=24;I16=11,13,0,0,886,32972,0,0,1369,80043,0,0,410,8736,0,0;QS=3,0;MQSB=0.702671;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,85:3:0 0,9,108:3:0 +17 3970 . T 0 . DP=24;I16=11,13,0,0,861,31313,0,0,1369,80043,0,0,405,8649,0,0;QS=3,0;MQSB=0.702671;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,83:3:0 0,9,104:3:0 +17 3971 . C 0 . DP=22;I16=11,11,0,0,815,30625,0,0,1249,72843,0,0,402,8590,0,0;QS=3,0;MQSB=0.751921;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,57:2:0 0,9,103:3:0 +17 3972 . C 0 . DP=22;I16=11,11,0,0,812,30486,0,0,1249,72843,0,0,399,8557,0,0;QS=3,0;MQSB=0.751921;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,55:2:0 0,9,96:3:0 +17 3973 . A 0 . DP=22;I16=11,11,0,0,795,28873,0,0,1249,72843,0,0,395,8501,0,0;QS=3,0;MQSB=0.751921;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,52:2:0 0,9,97:3:0 +17 3974 . C 0 . DP=22;I16=11,11,0,0,729,24447,0,0,1249,72843,0,0,392,8472,0,0;QS=3,0;MQSB=0.751921;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,55:2:0 0,9,78:3:0 +17 3975 . G 0 . DP=22;I16=11,11,0,0,717,24525,0,0,1249,72843,0,0,390,8470,0,0;QS=3,0;MQSB=0.751921;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,46:2:0 0,9,96:3:0 +17 3976 . C 0 . DP=22;I16=11,11,0,0,816,30652,0,0,1249,72843,0,0,387,8445,0,0;QS=3,0;MQSB=0.751921;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,55:2:0 0,9,97:3:0 +17 3977 . A 0 . DP=23;I16=11,11,0,0,740,25384,0,0,1249,72843,0,0,382,8346,0,0;QS=3,0;MQSB=0.751921;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,48:2:0 0,9,90:3:0 +17 3978 . C 0 . DP=23;I16=11,12,0,0,769,26631,0,0,1309,76443,0,0,377,8223,0,0;QS=3,0;MQSB=0.726094;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,47:2:0 0,9,103:3:0 +17 3979 . C 0 . DP=21;I16=9,11,0,0,744,28160,0,0,1152,67874,0,0,361,7905,0,0;QS=3,0;MQSB=0.885207;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,51:2:0 0,9,104:3:0 +17 3980 . T 0 . DP=21;I16=10,11,0,0,756,27872,0,0,1212,71474,0,0,367,7855,0,0;QS=3,0;MQSB=0.914611;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,51:2:0 0,9,98:3:0 +17 3981 . G 0 . DP=21;I16=10,11,0,0,785,29641,0,0,1212,71474,0,0,362,7710,0,0;QS=3,0;MQSB=0.914611;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,50:2:0 0,9,93:3:0 +17 3982 . C 0 . DP=21;I16=10,11,0,0,779,29495,0,0,1212,71474,0,0,357,7591,0,0;QS=3,0;MQSB=0.914611;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,55:2:0 0,9,97:3:0 +17 3983 . T 0 . DP=20;I16=9,11,0,0,720,26274,0,0,1155,68225,0,0,353,7497,0,0;QS=3,0;MQSB=0.993528;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,57:2:0 0,9,93:3:0 +17 3984 . A 0 . DP=21;I16=10,11,0,0,739,26279,0,0,1192,69594,0,0,348,7378,0,0;QS=3,0;MQSB=0.885602;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,53:2:0 0,9,80:3:0 +17 3985 . C 0 . DP=20;I16=10,10,0,0,728,26998,0,0,1132,65994,0,0,344,7234,0,0;QS=3,0;MQSB=0.902256;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,55:2:0 0,9,91:3:0 +17 3986 . A 0 . DP=20;I16=10,10,0,0,685,23815,0,0,1132,65994,0,0,340,7114,0,0;QS=3,0;MQSB=0.902256;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,56:2:0 0,9,84:3:0 +17 3987 . C 0 . DP=20;I16=10,10,0,0,736,28118,0,0,1132,65994,0,0,336,7018,0,0;QS=3,0;MQSB=0.902256;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,55:2:0 0,9,94:3:0 +17 3988 . T 0 . DP=21;I16=10,10,0,0,741,27797,0,0,1132,65994,0,0,332,6946,0,0;QS=3,0;MQSB=0.902256;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,58:2:0 0,9,91:3:0 +17 3989 . C 0 . DP=21;I16=10,11,0,0,729,26185,0,0,1192,69594,0,0,327,6801,0,0;QS=3,0;MQSB=0.885602;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,55:2:0 0,9,88:3:0 +17 3990 . C 0 . DP=21;I16=10,11,0,0,766,28674,0,0,1192,69594,0,0,322,6686,0,0;QS=3,0;MQSB=0.885602;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,55:2:0 0,9,95:3:0 +17 3991 . T 0 . DP=20;I16=9,11,0,0,729,27311,0,0,1132,65994,0,0,318,6600,0,0;QS=3,0;MQSB=0.850154;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,55:2:0 0,9,89:3:0 +17 3992 . T 0 . DP=19;I16=9,10,0,0,667,24173,0,0,1072,62394,0,0,313,6441,0,0;QS=3,0;MQSB=0.868634;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,56:2:0 0,6,72:2:0 +17 3993 . C 0 . DP=18;I16=9,9,0,0,701,27529,0,0,1012,58794,0,0,309,6307,0,0;QS=3,0;MQSB=0.888755;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,59:2:0 0,6,70:2:0 +17 3994 . T 0 . DP=19;I16=10,9,0,0,718,27520,0,0,1049,60163,0,0,305,6197,0,0;QS=3,0;MQSB=0.716531;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,58:2:0 0,6,72:2:0 +17 3995 . T 0 . DP=19;I16=9,9,0,0,641,23025,0,0,989,56563,0,0,277,5487,0,0;QS=3,0;MQSB=0.650623;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,53:2:0 0,6,69:2:0 +17 3996 . A 0 . DP=19;I16=9,9,0,0,665,24815,0,0,989,56563,0,0,274,5428,0,0;QS=3,0;MQSB=0.650623;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,54:2:0 0,6,73:2:0 +17 3997 . G C, 0 . DP=19;I16=10,8,0,1,645,23703,21,441,989,56563,60,3600,287,5843,6,36;QS=2.96023,0.0397727,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.716531;BQB=1;MQ0F=0 PL:DP:DV 0,24,255,42,255,255:15:1 0,6,57,6,57,57:2:0 0,6,60,6,60,60:2:0 +17 3998 . G 0 . DP=18;I16=9,8,0,0,626,23710,0,0,929,52963,0,0,265,5203,0,0;QS=3,0;MQSB=0.687289;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,58:2:0 0,3,36:1:0 +17 3999 . G A, 0 . DP=18;I16=9,7,0,1,596,22974,37,1369,869,49363,60,3600,263,5387,4,16;QS=2.92871,0.0712909,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.687289;BQB=1;MQ0F=0 PL:DP:DV 0,5,255,39,255,255:14:1 0,6,56,6,56,56:2:0 0,3,38,3,38,38:1:0 +17 4000 . C 0 . DP=18;I16=10,8,0,0,669,25389,0,0,989,56563,0,0,283,5753,0,0;QS=3,0;MQSB=0.751866;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,55:2:0 0,3,36:1:0 +17 4001 . T 0 . DP=18;I16=10,8,0,0,680,26006,0,0,989,56563,0,0,279,5727,0,0;QS=3,0;MQSB=0.751866;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,56:2:0 0,3,33:1:0 +17 4002 . G 0 . DP=17;I16=10,7,0,0,621,23281,0,0,929,52963,0,0,276,5724,0,0;QS=2,0;MQSB=0.79189;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,44:2:0 0,0,0:0:0 +17 4003 . A 0 . DP=17;I16=10,7,0,0,597,21507,0,0,929,52963,0,0,272,5692,0,0;QS=2,0;MQSB=0.79189;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,55:2:0 0,0,0:0:0 +17 4004 . T 0 . DP=15;I16=9,6,0,0,527,19031,0,0,849,48963,0,0,270,5678,0,0;QS=2,0;MQSB=0.957526;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,40:1:0 0,0,0:0:0 +17 4005 . A 0 . DP=15;I16=8,5,0,0,479,17731,0,0,729,41763,0,0,237,5195,0,0;QS=2,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,35:1:0 0,0,0:0:0 +17 4006 . T 0 . DP=15;I16=9,6,0,0,554,20776,0,0,849,48963,0,0,266,5698,0,0;QS=2,0;MQSB=0.957526;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,40:1:0 0,0,0:0:0 +17 4007 . T G, 0 . DP=15;I16=9,5,0,1,490,17810,15,225,789,45363,60,3600,245,5371,19,361;QS=1.96746,0.032538,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.957526;BQB=1;MQ0F=0 PL:DP:DV 0,26,255,39,255,255:14:1 0,3,41,3,41,41:1:0 0,0,0,0,0,0:0:0 +17 4008 . C 0 . DP=15;I16=9,6,0,0,488,16890,0,0,849,48963,0,0,262,5782,0,0;QS=2,0;MQSB=0.957526;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,30:1:0 0,0,0:0:0 +17 4009 . C 0 . DP=14;I16=9,5,0,0,524,20150,0,0,794,45938,0,0,261,5847,0,0;QS=2,0;MQSB=0.800737;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,40:1:0 0,0,0:0:0 +17 4010 . A 0 . DP=14;I16=9,5,0,0,523,19731,0,0,794,45938,0,0,259,5875,0,0;QS=2,0;MQSB=0.800737;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,41:1:0 0,0,0:0:0 +17 4011 . C 0 . DP=14;I16=9,5,0,0,489,17613,0,0,794,45938,0,0,257,5915,0,0;QS=2,0;MQSB=0.800737;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,41:1:0 0,0,0:0:0 +17 4012 . A 0 . DP=14;I16=7,5,0,0,365,11867,0,0,674,38738,0,0,223,5293,0,0;QS=2,0;MQSB=0.6821;MQ0F=0 PL:DP:DV 0,33,231:11:0 0,3,30:1:0 0,0,0:0:0 +17 4013 . C 0 . DP=14;I16=8,5,0,0,451,15885,0,0,734,42338,0,0,247,5995,0,0;QS=2,0;MQSB=0.765017;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,37:1:0 0,0,0:0:0 +17 4014 . A 0 . DP=12;I16=8,2,0,0,358,13372,0,0,554,31538,0,0,222,5404,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,213:9:0 0,3,34:1:0 0,0,0:0:0 +17 4015 . C 0 . DP=12;I16=8,2,0,0,350,12812,0,0,554,31538,0,0,222,5442,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,222:9:0 0,3,21:1:0 0,0,0:0:0 +17 4016 . C 0 . DP=12;I16=8,3,0,0,350,11956,0,0,614,35138,0,0,247,6109,0,0;QS=2,0;MQSB=0.829029;MQ0F=0 PL:DP:DV 0,30,215:10:0 0,3,32:1:0 0,0,0:0:0 +17 4017 . C 0 . DP=11;I16=5,2,0,0,227,7765,0,0,374,20738,0,0,173,4279,0,0;QS=2,0;MQSB=0.6;MQ0F=0 PL:DP:DV 0,18,161:6:0 0,3,20:1:0 0,0,0:0:0 +17 4018 . G 0 . DP=11;I16=8,2,0,0,284,8442,0,0,554,31538,0,0,249,6201,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,183:9:0 0,3,17:1:0 0,0,0:0:0 +17 4019 . C 0 . DP=11;I16=9,2,0,0,383,14427,0,0,614,35138,0,0,250,6250,0,0;QS=2,0;MQSB=0.777778;MQ0F=0 PL:DP:DV 0,30,228:10:0 0,3,33:1:0 0,0,0:0:0 +17 4020 . T 0 . DP=10;I16=8,2,0,0,362,13668,0,0,554,31538,0,0,250,6250,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,213:9:0 0,3,38:1:0 0,0,0:0:0 +17 4021 . A 0 . DP=10;I16=8,1,0,0,304,10512,0,0,494,27938,0,0,225,5625,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,177:8:0 0,3,33:1:0 0,0,0:0:0 +17 4022 . C 0 . DP=10;I16=7,2,0,0,310,11582,0,0,494,27938,0,0,225,5625,0,0;QS=2,0;MQSB=0.714286;MQ0F=0 PL:DP:DV 0,24,202:8:0 0,3,36:1:0 0,0,0:0:0 +17 4023 . A 0 . DP=10;I16=8,2,0,0,354,13116,0,0,554,31538,0,0,250,6250,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,209:9:0 0,3,40:1:0 0,0,0:0:0 +17 4024 . C 0 . DP=10;I16=8,2,0,0,361,13669,0,0,554,31538,0,0,250,6250,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,214:9:0 0,3,39:1:0 0,0,0:0:0 +17 4025 . T 0 . DP=10;I16=8,1,0,0,360,14488,0,0,494,27938,0,0,224,5576,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,199:8:0 0,3,42:1:0 0,0,0:0:0 +17 4026 . C 0 . DP=10;I16=8,2,0,0,329,11655,0,0,554,31538,0,0,248,6154,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,192:9:0 0,3,39:1:0 0,0,0:0:0 +17 4027 . C 0 . DP=10;I16=8,2,0,0,380,14888,0,0,554,31538,0,0,246,6060,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,231:9:0 0,3,38:1:0 0,0,0:0:0 +17 4028 . T 0 . DP=10;I16=8,2,0,0,333,12157,0,0,554,31538,0,0,244,5970,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,202:9:0 0,3,41:1:0 0,0,0:0:0 +17 4029 . T 0 . DP=10;I16=8,2,0,0,377,14333,0,0,554,31538,0,0,242,5884,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,225:9:0 0,3,38:1:0 0,0,0:0:0 +17 4030 . C 0 . DP=10;I16=8,2,0,0,348,12558,0,0,554,31538,0,0,240,5802,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,211:9:0 0,3,30:1:0 0,0,0:0:0 +17 4031 . T 0 . DP=10;I16=8,2,0,0,388,15302,0,0,554,31538,0,0,238,5724,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,229:9:0 0,3,39:1:0 0,0,0:0:0 +17 4032 . T 0 . DP=10;I16=8,2,0,0,341,11901,0,0,554,31538,0,0,236,5650,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,204:9:0 0,3,39:1:0 0,0,0:0:0 +17 4033 . A 0 . DP=10;I16=7,2,0,0,299,10717,0,0,494,27938,0,0,218,5324,0,0;QS=2,0;MQSB=0.714286;MQ0F=0 PL:DP:DV 0,24,193:8:0 0,3,38:1:0 0,0,0:0:0 +17 4034 . G 0 . DP=10;I16=8,2,0,0,347,12527,0,0,554,31538,0,0,231,5465,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,211:9:0 0,3,39:1:0 0,0,0:0:0 +17 4035 . G T, 0 . DP=10;I16=7,2,1,0,316,11900,13,169,494,27938,60,3600,202,4682,25,625;QS=1.9547,0.0452962,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.75;BQB=1;MQ0F=0 PL:DP:DV 0,13,195,24,198,200:9:1 0,3,31,3,31,31:1:0 0,0,0,0,0,0:0:0 +17 4036 . G 0 . DP=10;I16=8,1,0,0,269,8839,0,0,494,27938,0,0,198,4532,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,156:8:0 0,3,34:1:0 0,0,0:0:0 +17 4037 . C 0 . DP=10;I16=8,2,0,0,342,12466,0,0,554,31538,0,0,219,5015,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,210:9:0 0,3,30:1:0 0,0,0:0:0 +17 4038 . T 0 . DP=10;I16=8,2,0,0,335,12149,0,0,554,31538,0,0,215,4881,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,203:9:0 0,3,29:1:0 0,0,0:0:0 +17 4039 . G 0 . DP=10;I16=8,1,0,0,302,10798,0,0,494,27938,0,0,186,4130,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,180:8:0 0,3,31:1:0 0,0,0:0:0 +17 4040 . A 0 . DP=10;I16=8,2,0,0,380,14602,0,0,554,31538,0,0,207,4637,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,223:9:0 0,3,41:1:0 0,0,0:0:0 +17 4041 . T 0 . DP=10;I16=8,2,0,0,367,13633,0,0,554,31538,0,0,202,4478,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,216:9:0 0,3,40:1:0 0,0,0:0:0 +17 4042 . A 0 . DP=10;I16=8,2,0,0,337,11657,0,0,554,31538,0,0,197,4329,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,205:9:0 0,3,34:1:0 0,0,0:0:0 +17 4043 . T 0 . DP=10;I16=8,2,0,0,314,10428,0,0,554,31538,0,0,192,4190,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,190:9:0 0,3,35:1:0 0,0,0:0:0 +17 4044 . T 0 . DP=10;I16=8,2,0,0,333,11579,0,0,554,31538,0,0,187,4061,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,199:9:0 0,3,37:1:0 0,0,0:0:0 +17 4045 . C 0 . DP=10;I16=7,2,0,0,291,10099,0,0,494,27938,0,0,176,3906,0,0;QS=1,0;MQSB=0.714286;MQ0F=0 PL:DP:DV 0,27,204:9:0 0,0,0:0:0 0,0,0:0:0 +17 4046 . C 0 . DP=10;I16=8,2,0,0,356,13032,0,0,554,31538,0,0,177,3833,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,212:9:0 0,3,35:1:0 0,0,0:0:0 +17 4047 . A 0 . DP=10;I16=8,2,0,0,347,12557,0,0,554,31538,0,0,172,3734,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,204:9:0 0,3,40:1:0 0,0,0:0:0 +17 4048 . C 0 . DP=10;I16=8,2,0,0,342,12124,0,0,554,31538,0,0,167,3645,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,202:9:0 0,3,37:1:0 0,0,0:0:0 +17 4049 . G 0 . DP=10;I16=7,2,0,0,260,7786,0,0,494,27938,0,0,146,3310,0,0;QS=2,0;MQSB=0.714286;MQ0F=0 PL:DP:DV 0,24,173:8:0 0,3,24:1:0 0,0,0:0:0 +17 4050 . C 0 . DP=9;I16=6,2,0,0,291,10813,0,0,434,24338,0,0,157,3495,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL:DP:DV 0,24,204:8:0 0,0,0:0:0 0,0,0:0:0 +17 4051 . A 0 . DP=8;I16=5,2,0,0,259,9679,0,0,374,20738,0,0,146,3370,0,0;QS=1,0;MQSB=0.6;MQ0F=0 PL:DP:DV 0,21,192:7:0 0,0,0:0:0 0,0,0:0:0 +17 4052 . C 0 . DP=8;I16=5,2,0,0,247,9025,0,0,374,20738,0,0,143,3281,0,0;QS=1,0;MQSB=0.6;MQ0F=0 PL:DP:DV 0,21,190:7:0 0,0,0:0:0 0,0,0:0:0 +17 4053 . C 0 . DP=8;I16=6,2,0,0,254,9000,0,0,434,24338,0,0,146,3234,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL:DP:DV 0,24,184:8:0 0,0,0:0:0 0,0,0:0:0 +17 4054 . C 0 . DP=8;I16=3,2,0,0,160,5344,0,0,254,13538,0,0,122,2984,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,134:5:0 0,0,0:0:0 0,0,0:0:0 +17 4055 . G 0 . DP=8;I16=6,2,0,0,230,6982,0,0,434,24338,0,0,138,3066,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL:DP:DV 0,24,169:8:0 0,0,0:0:0 0,0,0:0:0 +17 4056 . C 0 . DP=8;I16=6,2,0,0,275,10153,0,0,434,24338,0,0,134,2994,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL:DP:DV 0,24,197:8:0 0,0,0:0:0 0,0,0:0:0 +17 4057 . T 0 . DP=8;I16=5,2,0,0,243,8603,0,0,374,20738,0,0,127,2877,0,0;QS=1,0;MQSB=0.6;MQ0F=0 PL:DP:DV 0,21,182:7:0 0,0,0:0:0 0,0,0:0:0 +17 4058 . A 0 . DP=7;I16=4,2,0,0,214,7742,0,0,314,17138,0,0,116,2728,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,171:6:0 0,0,0:0:0 0,0,0:0:0 +17 4059 . C 0 . DP=6;I16=4,2,0,0,204,7164,0,0,314,17138,0,0,119,2635,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,168:6:0 0,0,0:0:0 0,0,0:0:0 +17 4060 . A 0 . DP=6;I16=4,2,0,0,227,8683,0,0,314,17138,0,0,115,2501,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,177:6:0 0,0,0:0:0 0,0,0:0:0 +17 4061 . C 0 . DP=6;I16=4,2,0,0,193,6681,0,0,314,17138,0,0,111,2375,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,157:6:0 0,0,0:0:0 0,0,0:0:0 +17 4062 . T 0 . DP=6;I16=4,1,0,0,195,7621,0,0,254,13538,0,0,82,1632,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,151:5:0 0,0,0:0:0 0,0,0:0:0 +17 4063 . C 0 . DP=6;I16=4,2,0,0,216,7984,0,0,314,17138,0,0,102,2098,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,170:6:0 0,0,0:0:0 0,0,0:0:0 +17 4064 . C 0 . DP=6;I16=4,2,0,0,227,8747,0,0,314,17138,0,0,97,1949,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,177:6:0 0,0,0:0:0 0,0,0:0:0 +17 4065 . T 0 . DP=6;I16=4,2,0,0,202,6880,0,0,314,17138,0,0,92,1810,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,161:6:0 0,0,0:0:0 0,0,0:0:0 +17 4066 . T 0 . DP=5;I16=3,2,0,0,180,6554,0,0,254,13538,0,0,88,1680,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,153:5:0 0,0,0:0:0 0,0,0:0:0 +17 4067 . C 0 . DP=5;I16=3,2,0,0,181,6637,0,0,254,13538,0,0,84,1558,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,153:5:0 0,0,0:0:0 0,0,0:0:0 +17 4068 . T 0 . DP=5;I16=3,2,0,0,198,7868,0,0,254,13538,0,0,80,1444,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,164:5:0 0,0,0:0:0 0,0,0:0:0 +17 4069 . T 0 . DP=5;I16=3,2,0,0,177,6325,0,0,254,13538,0,0,76,1338,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,154:5:0 0,0,0:0:0 0,0,0:0:0 +17 4070 . A 0 . DP=5;I16=3,2,0,0,161,5263,0,0,254,13538,0,0,72,1240,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,140:5:0 0,0,0:0:0 0,0,0:0:0 +17 4071 . G 0 . DP=5;I16=3,2,0,0,166,5658,0,0,254,13538,0,0,68,1150,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,142:5:0 0,0,0:0:0 0,0,0:0:0 +17 4072 . G 0 . DP=5;I16=2,2,0,0,138,4974,0,0,194,9938,0,0,55,987,0,0;QS=1,0;MQSB=0;MQ0F=0 PL:DP:DV 0,12,122:4:0 0,0,0:0:0 0,0,0:0:0 +17 4073 . G 0 . DP=5;I16=3,2,0,0,156,5082,0,0,254,13538,0,0,60,994,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,136:5:0 0,0,0:0:0 0,0,0:0:0 +17 4074 . C 0 . DP=5;I16=3,2,0,0,160,5602,0,0,254,13538,0,0,56,928,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,142:5:0 0,0,0:0:0 0,0,0:0:0 +17 4075 . T 0 . DP=5;I16=3,2,0,0,187,7069,0,0,254,13538,0,0,52,870,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,155:5:0 0,0,0:0:0 0,0,0:0:0 +17 4076 . G 0 . DP=5;I16=3,2,0,0,174,6298,0,0,254,13538,0,0,48,820,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,149:5:0 0,0,0:0:0 0,0,0:0:0 +17 4077 . A 0 . DP=4;I16=3,1,0,0,138,4810,0,0,194,9938,0,0,44,728,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,12,121:4:0 0,0,0:0:0 0,0,0:0:0 +17 4078 . T 0 . DP=4;I16=3,1,0,0,143,5173,0,0,194,9938,0,0,40,644,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,12,124:4:0 0,0,0:0:0 0,0,0:0:0 +17 4079 . A 0 . DP=4;I16=3,1,0,0,121,3847,0,0,194,9938,0,0,36,568,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,12,107:4:0 0,0,0:0:0 0,0,0:0:0 +17 4080 . T 0 . DP=4;I16=3,0,0,0,106,3778,0,0,134,6338,0,0,25,451,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,9,87:3:0 0,0,0:0:0 0,0,0:0:0 +17 4081 . T 0 . DP=4;I16=3,1,0,0,106,2934,0,0,194,9938,0,0,28,440,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,12,94:4:0 0,0,0:0:0 0,0,0:0:0 +17 4082 . C 0 . DP=3;I16=2,1,0,0,110,4042,0,0,134,6338,0,0,25,387,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,9,103:3:0 0,0,0:0:0 0,0,0:0:0 +17 4083 . C 0 . DP=3;I16=2,1,0,0,104,3648,0,0,134,6338,0,0,22,340,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,9,98:3:0 0,0,0:0:0 0,0,0:0:0 +17 4084 . A 0 . DP=2;I16=1,1,0,0,78,3050,0,0,97,4969,0,0,20,298,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,6,74:2:0 0,0,0:0:0 0,0,0:0:0 +17 4085 . C 0 . DP=2;I16=1,1,0,0,62,1940,0,0,97,4969,0,0,18,260,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,6,62:2:0 0,0,0:0:0 0,0,0:0:0 +17 4086 . G 0 . DP=2;I16=1,1,0,0,56,1640,0,0,97,4969,0,0,16,226,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,6,56:2:0 0,0,0:0:0 0,0,0:0:0 +17 4087 . C 0 . DP=2;I16=1,1,0,0,69,2405,0,0,97,4969,0,0,14,196,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,6,68:2:0 0,0,0:0:0 0,0,0:0:0 +17 4088 . A 0 . DP=1;I16=1,0,0,0,39,1521,0,0,37,1369,0,0,13,169,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,37:1:0 0,0,0:0:0 0,0,0:0:0 +17 4089 . C 0 . DP=1;I16=1,0,0,0,36,1296,0,0,37,1369,0,0,12,144,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,36:1:0 0,0,0:0:0 0,0,0:0:0 +17 4090 . C 0 . DP=1;I16=1,0,0,0,33,1089,0,0,37,1369,0,0,11,121,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,33:1:0 0,0,0:0:0 0,0,0:0:0 +17 4091 . T 0 . DP=1;I16=1,0,0,0,36,1296,0,0,37,1369,0,0,10,100,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,36:1:0 0,0,0:0:0 0,0,0:0:0 +17 4092 . G 0 . DP=1;I16=1,0,0,0,37,1369,0,0,37,1369,0,0,9,81,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,37:1:0 0,0,0:0:0 0,0,0:0:0 +17 4093 . C 0 . DP=1;I16=1,0,0,0,35,1225,0,0,37,1369,0,0,8,64,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,35:1:0 0,0,0:0:0 0,0,0:0:0 +17 4094 . T 0 . DP=1;I16=1,0,0,0,40,1600,0,0,37,1369,0,0,7,49,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,37:1:0 0,0,0:0:0 0,0,0:0:0 +17 4095 . A 0 . DP=1;I16=1,0,0,0,35,1225,0,0,37,1369,0,0,6,36,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,35:1:0 0,0,0:0:0 0,0,0:0:0 +17 4096 . C 0 . DP=1;I16=1,0,0,0,32,1024,0,0,37,1369,0,0,5,25,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,32:1:0 0,0,0:0:0 0,0,0:0:0 +17 4097 . A 0 . DP=1;I16=1,0,0,0,35,1225,0,0,37,1369,0,0,4,16,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,35:1:0 0,0,0:0:0 0,0,0:0:0 +17 4098 . C 0 . DP=1;I16=1,0,0,0,31,961,0,0,37,1369,0,0,3,9,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,31:1:0 0,0,0:0:0 0,0,0:0:0 +17 4099 . T 0 . DP=1;I16=1,0,0,0,32,1024,0,0,37,1369,0,0,2,4,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,32:1:0 0,0,0:0:0 0,0,0:0:0 +17 4100 . C 0 . DP=1;I16=1,0,0,0,27,729,0,0,37,1369,0,0,1,1,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,27:1:0 0,0,0:0:0 0,0,0:0:0 +17 4101 . C 0 . DP=1;I16=1,0,0,0,26,676,0,0,37,1369,0,0,0,0,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,3,26:1:0 0,0,0:0:0 0,0,0:0:0 diff --git a/test/mpileup.cAls.out b/test/mpileup.cAls.out new file mode 100644 index 0000000..6597968 --- /dev/null +++ b/test/mpileup.cAls.out @@ -0,0 +1,40 @@ +##fileformat=VCFv4.2 +##FILTER= +##samtoolsVersion=1.1-19-g6b249e2+htslib-1.1-74-g845c515 +##samtoolsCommand=samtools mpileup -uvDV -b xxx//mpileup.bam.list -f xxx//mpileup.ref.fa.gz +##reference=file://xxx//mpileup.ref.fa.gz +##contig= +##ALT= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT HG00100 HG00101 HG00102 +17 1 . A G,T 52 . DP=11;MQ0F=0;AC=0,0;AN=0;DP4=11,0,0,0;MQ=29 GT:PL:DP:DV ./.:0,0,0,0,0,0:5:0 ./.:.:3:0 ./.:.:3:0 +17 2 . A T,G 52 . DP=11;MQ0F=0;AC=0,0;AN=0;DP4=11,0,0,0;MQ=29 GT:PL:DP:DV ./.:0,0,0,0,0,0:5:0 ./.:.:3:0 ./.:.:3:0 +17 3 . A C 26.0007 . DP=11;MQ0F=0;AC=0;AN=0;DP4=11,0,0,0;MQ=29 GT:PL:DP:DV ./.:0,0,0:5:0 ./.:.:3:0 ./.:.:3:0 +17 4 . A G,T,C 21.815 . DP=11;MQ0F=0;AC=0,0,0;AN=2;DP4=11,0,0,0;MQ=29 GT:PL:DP:DV 0/0:1,2,3,7,8,10,11,12,14,15:5:0 ./.:.:3:0 ./.:.:3:0 +17 5 . A G,T 26.0007 . DP=11;MQ0F=0;AC=0,0;AN=0;DP4=11,0,0,0;MQ=29 GT:PL:DP:DV ./.:0,0,0,0,0,0:5:0 ./.:.:3:0 ./.:.:3:0 +17 6 . A T,G 26.0007 . DP=11;MQ0F=0;AC=0,0;AN=0;DP4=11,0,0,0;MQ=29 GT:PL:DP:DV ./.:0,0,0,0,0,0:5:0 ./.:.:3:0 ./.:.:3:0 +17 7 . A T,G,C 21.5769 . DP=11;MQ0F=0;AC=0,0,0;AN=2;DP4=11,0,0,0;MQ=29 GT:PL:DP:DV 0/0:1,2,3,4,5,6,2,3,5,3:5:0 ./.:.:3:0 ./.:.:3:0 +17 828 . T C 409 . DP=25;VDB=0.842082;SGB=-4.20907;RPB=0.950652;MQB=1;MQSB=1;BQB=0.929717;MQ0F=0;ICB=0.8;HOB=0.222222;AC=4;AN=6;DP4=2,4,8,11;MQ=60 GT:PL:DP:DV 0/1:211,0,35:12:10 0/1:116,0,91:9:5 1/1:120,12,0:4:4 +17 1665 . T C 3.10665 . DP=20;VDB=0.1;SGB=0.346553;RPB=0.222222;MQB=0.611111;MQSB=0.988166;BQB=0.944444;MQ0F=0;ICB=0.128205;HOB=0.0555556;AC=1;AN=6;DP4=7,11,1,1;MQ=55 GT:PL:DP:DV 0/0:0,21,185:7:0 0/0:0,27,222:9:0 0/1:35,0,51:4:2 +17 2220 . G C 189 . DP=21;VDB=0.532753;SGB=-3.51597;RPB=0.964198;MQB=0.898397;MQSB=0.875769;BQB=0.0354359;MQ0F=0;AC=0;AN=6;DP4=6,2,1,11;MQ=58 GT:PL:DP:DV 0/0:139,157,255:12:6 0/0:69,75,119:4:2 0/0:131,131,131:4:4 +17 2564 . A AG 166 . DP=15;VDB=0.690812;SGB=-3.20711;RPB=0.197899;MQB=1;MQSB=1;BQB=0.965069;MQ0F=0;AC=0;AN=6;DP4=1,4,4,5;MQ=60 GT:PL:DP:DV 0/0:88,98,171:6:3 0/0:57,63,117:4:2 0/0:124,124,124:4:4 diff --git a/test/mpileup.ped b/test/mpileup.ped new file mode 100644 index 0000000..c4226c6 --- /dev/null +++ b/test/mpileup.ped @@ -0,0 +1,3 @@ +HG00100 HG00100 0 0 2 0 +HG00101 HG00101 0 0 1 0 +HG00102 HG00102 0 0 2 0 diff --git a/test/mpileup.ploidy b/test/mpileup.ploidy new file mode 100644 index 0000000..b9eba8a --- /dev/null +++ b/test/mpileup.ploidy @@ -0,0 +1,4 @@ +X 1 1000 M 1 +X 3104 5000 M 1 +* * * M 2 +* * * F 2 diff --git a/test/mpileup.samples b/test/mpileup.samples new file mode 100644 index 0000000..be818ea --- /dev/null +++ b/test/mpileup.samples @@ -0,0 +1,3 @@ +HG00100 F +HG00101 M +HG00102 F diff --git a/test/mpileup.tab b/test/mpileup.tab new file mode 100644 index 0000000..1930ea0 --- /dev/null +++ b/test/mpileup.tab @@ -0,0 +1,11 @@ +17 1 A,G,T +17 2 A,T,G +17 3 A,C +17 4 A,C,T,G +17 5 A,G,T +17 6 A,T,G +17 7 A,T,G,C +17 828 T,C +17 1665 T,C +17 2220 G,C +17 2564 A,AG diff --git a/test/mpileup.vcf b/test/mpileup.vcf new file mode 100644 index 0000000..155af1b --- /dev/null +++ b/test/mpileup.vcf @@ -0,0 +1,4127 @@ +##fileformat=VCFv4.2 +##FILTER= +##samtoolsVersion=1.1-19-g6b249e2+htslib-1.1-74-g845c515 +##samtoolsCommand=samtools mpileup -uvDV -b xxx//mpileup.bam.list -f xxx//mpileup.ref.fa.gz +##reference=file://xxx//mpileup.ref.fa.gz +##contig= +##ALT= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT HG00100 HG00101 HG00102 +17 1 . A G,X,T,C 0 . DP=11;I16=11,0,0,0,452,18594,0,0,319,9251,0,0,223,4959,0,0;QS=1,1,0,1,1;MQ0F=0 PL:DP:DV 0,0,0,0,0,0,.,.,.,.,.,.,.,.,.:5:0 .:3:0 .:3:0 +17 2 . A G,X,T,C 0 . DP=11;I16=11,0,0,0,452,18594,0,0,319,9251,0,0,223,4959,0,0;QS=1,1,0,1,1;MQ0F=0 PL:DP:DV 0,0,0,0,0,0,.,.,.,.,.,.,.,.,.:5:0 .:3:0 .:3:0 +17 3 . A G,X,T,C 0 . DP=11;I16=11,0,0,0,452,18594,0,0,319,9251,0,0,223,4959,0,0;QS=1,1,0,1,1;MQ0F=0 PL:DP:DV 0,0,0,0,0,0,.,.,.,.,.,.,.,.,.:5:0 .:3:0 .:3:0 +17 4 . A G,X,T,C 0 . DP=11;I16=11,0,0,0,452,18594,0,0,319,9251,0,0,223,4959,0,0;QS=1,1,0,1,1;MQ0F=0 PL:DP:DV 1,2,3,4,5,6,7,8,9,10,11,12,13,14,15:5:0 .:3:0 .:3:0 +17 5 . A X,G 0 . DP=11;I16=11,0,0,0,452,18594,0,0,319,9251,0,0,223,4959,0,0;QS=1,0,1;MQ0F=0 PL:DP:DV 0,0,0,0,0,0:5:0 .:3:0 .:3:0 +17 6 . A X,G 0 . DP=11;I16=11,0,0,0,452,18594,0,0,319,9251,0,0,223,4959,0,0;QS=1,0,1;MQ0F=0 PL:DP:DV 0,0,0,0,0,0:5:0 .:3:0 .:3:0 +17 7 . A X,G 0 . DP=11;I16=11,0,0,0,452,18594,0,0,319,9251,0,0,223,4959,0,0;QS=1,0,1;MQ0F=0 PL:DP:DV 1,2,3,4,5,6:5:0 .:3:0 .:3:0 +17 8 . T 0 . DP=11;I16=11,0,0,0,465,19677,0,0,319,9251,0,0,238,5354,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 +17 9 . C 0 . DP=11;I16=11,0,0,0,447,18205,0,0,319,9251,0,0,239,5391,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 +17 10 . A 0 . DP=11;I16=11,0,0,0,426,16756,0,0,319,9251,0,0,240,5438,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,69:3:0 +17 11 . C 0 . DP=11;I16=11,0,0,0,413,15603,0,0,319,9251,0,0,241,5495,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 +17 12 . C 0 . DP=11;I16=11,0,0,0,438,17506,0,0,319,9251,0,0,242,5562,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 +17 13 . C 0 . DP=11;I16=11,0,0,0,437,17463,0,0,319,9251,0,0,243,5639,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 +17 14 . T 0 . DP=11;I16=11,0,0,0,453,18715,0,0,319,9251,0,0,242,5628,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 +17 15 . G 0 . DP=11;I16=11,0,0,0,439,17599,0,0,319,9251,0,0,240,5580,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 +17 16 . T 0 . DP=11;I16=11,0,0,0,426,16546,0,0,319,9251,0,0,238,5544,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 +17 17 . T 0 . DP=11;I16=11,0,0,0,407,15195,0,0,319,9251,0,0,235,5469,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,15,100:5:0 0,9,72:3:0 0,9,72:3:0 +17 18 . C 0 . DP=12;I16=12,0,0,0,450,17136,0,0,379,12851,0,0,231,5353,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,113:6:0 0,9,72:3:0 0,9,72:3:0 +17 19 . C 0 . DP=13;I16=13,0,0,0,502,19652,0,0,439,16451,0,0,228,5246,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,112:6:0 0,12,89:4:0 0,9,72:3:0 +17 20 . T 0 . DP=13;I16=13,0,0,0,532,21878,0,0,439,16451,0,0,226,5150,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,116:6:0 0,12,98:4:0 0,9,72:3:0 +17 21 . G 0 . DP=13;I16=13,0,0,0,498,19254,0,0,439,16451,0,0,224,5066,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,117:6:0 0,12,94:4:0 0,9,72:3:0 +17 22 . C 0 . DP=13;I16=13,0,0,0,511,20289,0,0,470,19210,0,0,223,4993,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,18,115:6:0 0,12,91:4:0 0,9,76:3:0 +17 23 . A 0 . DP=14;I16=14,0,0,0,513,19399,0,0,530,22810,0,0,223,4931,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,133:7:0 0,12,82:4:0 0,9,82:3:0 +17 24 . T 0 . DP=14;I16=14,0,0,0,534,20540,0,0,530,22810,0,0,224,4882,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,131:7:0 0,12,96:4:0 0,9,80:3:0 +17 25 . A 0 . DP=15;I16=15,0,0,0,561,21133,0,0,590,26410,0,0,225,4847,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,140:8:0 0,12,96:4:0 0,9,81:3:0 +17 26 . G 0 . DP=15;I16=15,0,0,0,591,23429,0,0,590,26410,0,0,227,4827,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,151:8:0 0,12,96:4:0 0,9,81:3:0 +17 27 . A 0 . DP=15;I16=15,0,0,0,588,23120,0,0,590,26410,0,0,229,4823,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,146:8:0 0,12,98:4:0 0,9,83:3:0 +17 28 . T 0 . DP=16;I16=16,0,0,0,605,23001,0,0,650,30010,0,0,231,4835,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,147:8:0 0,12,97:4:0 0,12,101:4:0 +17 29 . A 0 . DP=17;I16=17,0,0,0,615,22533,0,0,710,33610,0,0,234,4864,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,146:8:0 0,15,102:5:0 0,12,104:4:0 +17 30 . A 0 . DP=17;I16=17,0,0,0,660,25914,0,0,710,33610,0,0,238,4912,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,149:8:0 0,15,115:5:0 0,12,108:4:0 +17 31 . T 0 . DP=17;I16=17,0,0,0,656,25392,0,0,710,33610,0,0,242,4980,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,150:8:0 0,15,113:5:0 0,12,105:4:0 +17 32 . T 0 . DP=17;I16=17,0,0,0,605,21789,0,0,741,36369,0,0,247,5067,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,143:8:0 0,15,104:5:0 0,12,104:4:0 +17 33 . G 0 . DP=17;I16=17,0,0,0,659,25757,0,0,741,36369,0,0,252,5124,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,158:8:0 0,15,118:5:0 0,12,105:4:0 +17 34 . C 0 . DP=17;I16=17,0,0,0,658,25704,0,0,741,36369,0,0,257,5203,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,151:8:0 0,15,121:5:0 0,12,106:4:0 +17 35 . A 0 . DP=18;I16=18,0,0,0,677,25881,0,0,801,39969,0,0,262,5304,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,152:8:0 0,15,109:5:0 0,15,121:5:0 +17 36 . T 0 . DP=18;I16=18,0,0,0,678,25796,0,0,801,39969,0,0,268,5428,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,151:8:0 0,15,114:5:0 0,15,125:5:0 +17 37 . G 0 . DP=18;I16=18,0,0,0,685,26291,0,0,801,39969,0,0,274,5576,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,157:8:0 0,15,116:5:0 0,15,126:5:0 +17 38 . A 0 . DP=18;I16=18,0,0,0,697,27245,0,0,801,39969,0,0,280,5748,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,152:8:0 0,15,116:5:0 0,15,129:5:0 +17 39 . C 0 . DP=16;I16=16,0,0,0,591,22311,0,0,743,38287,0,0,288,5942,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,148:7:0 0,12,94:4:0 0,15,123:5:0 +17 40 . A 0 . DP=16;I16=16,0,0,0,630,24896,0,0,743,38287,0,0,295,6107,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,146:7:0 0,12,104:4:0 0,15,127:5:0 +17 41 . A 0 . DP=17;I16=17,0,0,0,645,24685,0,0,803,41887,0,0,302,6294,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,151:8:0 0,12,104:4:0 0,15,131:5:0 +17 42 . T 0 . DP=17;I16=17,0,0,0,618,23118,0,0,803,41887,0,0,310,6504,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,155:8:0 0,12,82:4:0 0,15,127:5:0 +17 43 . T 0 . DP=17;I16=17,0,0,0,631,23689,0,0,803,41887,0,0,318,6738,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,151:8:0 0,12,101:4:0 0,15,129:5:0 +17 44 . G 0 . DP=17;I16=17,0,0,0,664,26162,0,0,803,41887,0,0,324,6896,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,164:8:0 0,12,100:4:0 0,15,129:5:0 +17 45 . C 0 . DP=17;I16=17,0,0,0,657,25525,0,0,803,41887,0,0,329,7027,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,163:8:0 0,12,108:4:0 0,15,125:5:0 +17 46 . C 0 . DP=17;I16=17,0,0,0,646,25244,0,0,803,41887,0,0,334,7180,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,161:8:0 0,12,98:4:0 0,15,131:5:0 +17 47 . T 0 . DP=17;I16=17,0,0,0,700,28998,0,0,803,41887,0,0,339,7355,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,165:8:0 0,12,110:4:0 0,15,136:5:0 +17 48 . T 0 . DP=17;I16=17,0,0,0,648,25020,0,0,803,41887,0,0,343,7501,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,155:8:0 0,12,105:4:0 0,15,131:5:0 +17 49 . G 0 . DP=18;I16=18,0,0,0,686,26674,0,0,832,42728,0,0,346,7616,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,158:8:0 0,15,119:5:0 0,15,128:5:0 +17 50 . T 0 . DP=18;I16=17,0,0,0,650,24972,0,0,772,39128,0,0,332,7426,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,155:8:0 0,12,101:4:0 0,15,128:5:0 +17 51 . C 0 . DP=18;I16=18,0,0,0,681,26529,0,0,832,42728,0,0,353,7853,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,167:8:0 0,15,99:5:0 0,15,127:5:0 +17 52 . C 0 . DP=18;I16=17,0,0,0,645,24983,0,0,803,41887,0,0,353,7965,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,164:8:0 0,12,99:4:0 0,15,128:5:0 +17 53 . C 0 . DP=18;I16=18,0,0,0,687,26735,0,0,832,42728,0,0,359,8113,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,164:8:0 0,15,113:5:0 0,15,132:5:0 +17 54 . T 0 . DP=18;I16=18,0,0,0,736,30194,0,0,832,42728,0,0,361,8219,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,163:8:0 0,15,128:5:0 0,15,136:5:0 +17 55 . G 0 . DP=18;I16=18,0,0,0,674,26082,0,0,832,42728,0,0,362,8290,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,168:8:0 0,15,112:5:0 0,15,122:5:0 +17 56 . C 0 . DP=18;I16=18,0,0,0,701,27645,0,0,832,42728,0,0,363,8375,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,162:8:0 0,15,121:5:0 0,15,131:5:0 +17 57 . T 0 . DP=18;I16=17,0,0,0,694,29118,0,0,803,41887,0,0,356,8410,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,163:8:0 0,12,117:4:0 0,15,138:5:0 +17 58 . G 0 . DP=17;I16=16,0,0,0,616,24356,0,0,774,41046,0,0,356,8454,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,159:7:0 0,12,95:4:0 0,15,131:5:0 +17 59 . A 0 . DP=17;I16=17,0,0,0,656,26038,0,0,803,41887,0,0,366,8606,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,155:7:0 0,15,116:5:0 0,15,134:5:0 +17 60 . A 0 . DP=17;I16=17,0,0,0,663,26463,0,0,803,41887,0,0,367,8687,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,151:7:0 0,15,127:5:0 0,15,138:5:0 +17 61 . T 0 . DP=17;I16=16,0,0,0,605,23215,0,0,774,41046,0,0,355,8583,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,152:7:0 0,12,101:4:0 0,15,131:5:0 +17 62 . G 0 . DP=18;I16=17,0,0,0,646,24868,0,0,834,44646,0,0,353,8557,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,158:7:0 0,12,103:4:0 0,18,141:6:0 +17 63 . T 0 . DP=18;I16=17,0,0,0,590,21682,0,0,803,41887,0,0,341,8111,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,148:7:0 0,12,80:4:0 0,18,144:6:0 +17 64 . G 0 . DP=19;I16=19,0,0,0,696,26416,0,0,923,49087,0,0,366,8758,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,169:8:0 0,15,103:5:0 0,18,142:6:0 +17 65 . C 0 . DP=18;I16=18,0,0,0,686,26512,0,0,894,48246,0,0,367,8743,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,163:7:0 0,15,116:5:0 0,18,147:6:0 +17 66 . T 0 . DP=18;I16=17,0,0,0,691,28315,0,0,834,44646,0,0,342,8068,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,164:7:0 0,12,110:4:0 0,18,153:6:0 +17 67 . C 0 . DP=17;I16=17,0,0,0,645,25313,0,0,834,44646,0,0,341,7983,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,163:7:0 0,12,94:4:0 0,18,147:6:0 +17 68 . T 0 . DP=17;I16=17,0,0,0,691,28307,0,0,834,44646,0,0,339,7863,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,165:7:0 0,12,108:4:0 0,18,151:6:0 +17 69 . G 0 . DP=17;I16=17,0,0,0,657,25721,0,0,865,47405,0,0,338,7758,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,172:8:0 0,9,93:3:0 0,18,142:6:0 +17 70 . G 0 . DP=17;I16=16,0,0,0,575,21391,0,0,836,46564,0,0,317,7227,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,162:8:0 0,6,64:2:0 0,18,141:6:0 +17 71 . G 0 . DP=17;I16=15,0,0,0,571,21975,0,0,776,42964,0,0,307,7029,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,170:8:0 0,6,72:2:0 0,15,130:5:0 +17 72 . G 0 . DP=17;I16=15,0,0,0,572,22002,0,0,776,42964,0,0,305,6907,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,171:8:0 0,6,65:2:0 0,15,131:5:0 +17 73 . T 0 . DP=18;I16=16,0,0,0,623,25301,0,0,836,46564,0,0,314,6918,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,158:8:0 0,6,94:2:0 0,18,143:6:0 +17 74 . C 0 . DP=18;I16=17,0,0,0,674,28110,0,0,865,47405,0,0,338,7468,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,176:8:0 0,9,106:3:0 0,18,141:6:0 +17 75 . T 0 . DP=18;I16=16,0,0,0,685,30675,0,0,836,46564,0,0,312,6782,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,175:8:0 0,6,90:2:0 0,18,150:6:0 +17 76 . C 0 . DP=18;I16=17,0,0,0,683,29481,0,0,865,47405,0,0,336,7360,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,174:8:0 0,9,98:3:0 0,18,148:6:0 +17 77 . T 0 . DP=18;I16=16,0,0,0,710,33072,0,0,836,46564,0,0,310,6702,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,179:8:0 0,6,92:2:0 0,18,154:6:0 +17 78 . G 0 . DP=18;I16=16,0,0,0,692,31158,0,0,836,46564,0,0,309,6683,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,180:8:0 0,6,94:2:0 0,18,149:6:0 +17 79 . G 0 . DP=18;I16=15,0,0,0,605,26629,0,0,776,42964,0,0,283,6053,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,168:8:0 0,3,60:1:0 0,18,149:6:0 +17 80 . G 0 . DP=18;I16=17,0,0,0,688,30128,0,0,865,47405,0,0,332,7312,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,173:8:0 0,9,106:3:0 0,18,151:6:0 +17 81 . G 0 . DP=18;I16=16,0,0,0,631,27429,0,0,836,46564,0,0,326,7310,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,165:7:0 0,9,97:3:0 0,18,145:6:0 +17 82 . T 0 . DP=18;I16=15,0,0,0,559,22735,0,0,776,42964,0,0,280,6122,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,154:8:0 0,3,60:1:0 0,18,131:6:0 +17 83 . C 0 . DP=18;I16=16,0,0,0,622,27146,0,0,836,46564,0,0,304,6798,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,170:8:0 0,6,75:2:0 0,18,145:6:0 +17 84 . T 0 . DP=18;I16=17,0,0,0,705,32445,0,0,865,47405,0,0,328,7488,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,181:8:0 0,9,85:3:0 0,18,154:6:0 +17 85 . C 0 . DP=18;I16=17,0,0,0,708,31222,0,0,865,47405,0,0,327,7567,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,181:8:0 0,9,108:3:0 0,18,153:6:0 +17 86 . A 0 . DP=18;I16=17,0,0,0,692,29540,0,0,865,47405,0,0,326,7660,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,169:8:0 0,9,111:3:0 0,18,149:6:0 +17 87 . C 0 . DP=18;I16=17,0,0,0,683,29493,0,0,896,50164,0,0,326,7766,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,174:8:0 0,9,103:3:0 0,18,148:6:0 +17 88 . C 0 . DP=18;I16=17,0,0,0,703,31005,0,0,896,50164,0,0,326,7834,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,174:8:0 0,9,113:3:0 0,18,153:6:0 +17 89 . C 0 . DP=18;I16=17,0,0,0,697,30875,0,0,896,50164,0,0,326,7914,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,176:8:0 0,9,103:3:0 0,18,154:6:0 +17 90 . A 0 . DP=17;I16=16,0,0,0,668,29732,0,0,867,49323,0,0,326,7954,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,173:8:0 0,9,114:3:0 0,15,138:5:0 +17 91 . C 0 . DP=16;I16=15,0,0,0,613,26409,0,0,838,48482,0,0,327,8001,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,170:7:0 0,9,113:3:0 0,15,133:5:0 +17 92 . G 0 . DP=16;I16=15,0,0,0,499,18731,0,0,838,48482,0,0,328,8054,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,143:7:0 0,9,100:3:0 0,15,96:5:0 +17 93 . A 0 . DP=16;I16=15,0,0,0,635,28655,0,0,869,51241,0,0,329,8063,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,167:7:0 0,9,108:3:0 0,15,145:5:0 +17 94 . C 0 . DP=16;I16=15,0,0,0,607,25893,0,0,869,51241,0,0,331,8079,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,21,166:7:0 0,9,105:3:0 0,15,135:5:0 +17 95 . C 0 . DP=17;I16=15,0,0,0,615,26761,0,0,900,54000,0,0,306,7378,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,178:8:0 0,6,91:2:0 0,15,135:5:0 +17 96 . A 0 . DP=17;I16=16,0,0,0,625,26705,0,0,929,54841,0,0,332,7936,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,172:8:0 0,9,99:3:0 0,15,134:5:0 +17 97 . A 0 . DP=18;I16=17,0,0,0,675,29017,0,0,958,55682,0,0,333,7879,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,179:9:0 0,9,104:3:0 0,15,145:5:0 +17 98 . C 0 . DP=18;I16=17,0,0,0,655,27231,0,0,958,55682,0,0,333,7735,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,179:9:0 0,9,105:3:0 0,15,131:5:0 +17 99 . T 0 . DP=18;I16=17,0,0,0,720,32840,0,0,958,55682,0,0,333,7607,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,186:9:0 0,9,115:3:0 0,15,153:5:0 +17 100 . C 0 . DP=18;I16=17,0,0,0,688,29762,0,0,958,55682,0,0,332,7446,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,189:9:0 0,9,108:3:0 0,15,134:5:0 +17 101 . C 0 . DP=18;I16=17,0,0,0,650,27530,0,0,958,55682,0,0,331,7303,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,182:9:0 0,9,99:3:0 0,15,132:5:0 +17 102 . C 0 . DP=18;I16=17,0,0,0,695,30453,0,0,958,55682,0,0,330,7178,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,188:9:0 0,9,111:3:0 0,15,139:5:0 +17 103 . T 0 . DP=18;I16=16,0,0,0,692,31998,0,0,929,54841,0,0,323,7035,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,189:8:0 0,9,108:3:0 0,15,147:5:0 +17 104 . G 0 . DP=18;I16=15,0,0,0,611,26723,0,0,900,54000,0,0,295,6259,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,178:8:0 0,6,89:2:0 0,15,133:5:0 +17 105 . G 0 . DP=19;I16=17,0,0,0,604,23936,0,0,989,58441,0,0,317,6751,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,170:9:0 0,9,97:3:0 0,15,125:5:0 +17 106 . G 0 . DP=19;I16=17,0,0,0,644,26574,0,0,989,58441,0,0,299,6093,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,30,190:10:0 0,6,85:2:0 0,15,124:5:0 +17 107 . C 0 . DP=19;I16=17,0,0,0,694,30064,0,0,989,58441,0,0,313,6543,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,192:9:0 0,9,108:3:0 0,15,136:5:0 +17 108 . C 0 . DP=19;I16=17,0,0,0,692,30148,0,0,989,58441,0,0,310,6420,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,190:9:0 0,9,108:3:0 0,15,135:5:0 +17 109 . T 0 . DP=19;I16=17,0,0,0,741,34273,0,0,989,58441,0,0,307,6319,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,195:9:0 0,9,110:3:0 0,15,150:5:0 +17 110 . G 0 . DP=19;I16=17,0,0,0,704,31276,0,0,989,58441,0,0,304,6240,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,194:9:0 0,9,104:3:0 0,15,136:5:0 +17 111 . G 0 . DP=19;I16=16,0,0,0,584,24362,0,0,929,54841,0,0,272,5416,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,30,167:10:0 0,6,88:2:0 0,12,118:4:0 +17 112 . C 0 . DP=19;I16=17,0,0,0,680,29854,0,0,989,58441,0,0,296,6052,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,191:9:0 0,9,95:3:0 0,15,135:5:0 +17 113 . A 0 . DP=19;I16=16,0,0,0,645,28035,0,0,960,57600,0,0,266,5318,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,176:9:0 0,6,87:2:0 0,15,139:5:0 +17 114 . C 0 . DP=19;I16=17,0,0,0,674,28788,0,0,989,58441,0,0,286,5856,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,182:9:0 0,9,103:3:0 0,15,133:5:0 +17 115 . C 0 . DP=21;I16=18,0,0,0,708,30546,0,0,1049,62041,0,0,274,5490,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,30,189:10:0 0,6,89:2:0 0,18,147:6:0 +17 116 . A 0 . DP=21;I16=17,1,0,0,727,31755,0,0,1049,62041,0,0,253,5079,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,183:9:0 0,6,90:2:0 0,21,175:7:0 +17 117 . G 0 . DP=21;I16=17,1,0,0,723,31221,0,0,1049,62041,0,0,249,5019,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,186:9:0 0,6,86:2:0 0,21,177:7:0 +17 118 . G 0 . DP=20;I16=16,1,0,0,636,26574,0,0,958,55682,0,0,266,5426,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,175:9:0 0,3,60:1:0 0,21,162:7:0 +17 119 . G 0 . DP=19;I16=16,1,0,0,629,26439,0,0,958,55682,0,0,267,5553,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,175:8:0 0,6,73:2:0 0,21,160:7:0 +17 120 . A 0 . DP=19;I16=16,1,0,0,672,29188,0,0,958,55682,0,0,264,5518,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,175:8:0 0,6,83:2:0 0,21,171:7:0 +17 121 . G 0 . DP=19;I16=16,1,0,0,662,28460,0,0,958,55682,0,0,260,5454,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,181:8:0 0,6,80:2:0 0,21,168:7:0 +17 122 . C 0 . DP=20;I16=17,1,0,0,716,31224,0,0,1018,59282,0,0,256,5410,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,181:8:0 0,9,99:3:0 0,21,178:7:0 +17 123 . T 0 . DP=18;I16=15,1,0,0,661,29997,0,0,898,52082,0,0,255,5385,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,167:7:0 0,9,112:3:0 0,18,166:6:0 +17 124 . T 0 . DP=19;I16=17,1,0,0,626,24802,0,0,987,56523,0,0,279,6003,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,154:9:0 0,9,104:3:0 0,18,154:6:0 +17 125 . A 0 . DP=18;I16=15,1,0,0,611,25689,0,0,898,52082,0,0,254,5340,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,154:7:0 0,9,104:3:0 0,18,162:6:0 +17 126 . A 0 . DP=18;I16=16,1,0,0,648,27366,0,0,927,52923,0,0,279,5947,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,162:8:0 0,9,107:3:0 0,18,174:6:0 +17 127 . C 0 . DP=18;I16=16,1,0,0,646,26972,0,0,927,52923,0,0,279,5949,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,163:8:0 0,9,109:3:0 0,18,160:6:0 +17 128 . A 0 . DP=18;I16=16,1,0,0,673,28797,0,0,927,52923,0,0,279,5971,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,169:8:0 0,9,111:3:0 0,18,162:6:0 +17 129 . A 0 . DP=17;I16=15,1,0,0,645,27891,0,0,867,49323,0,0,280,6012,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,168:8:0 0,9,113:3:0 0,15,159:5:0 +17 130 . A 0 . DP=17;I16=15,1,0,0,641,27295,0,0,867,49323,0,0,281,6071,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,169:8:0 0,9,113:3:0 0,15,152:5:0 +17 131 . C 0 . DP=16;I16=14,1,0,0,606,25732,0,0,838,48482,0,0,256,5472,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,167:7:0 0,9,110:3:0 0,15,147:5:0 +17 132 . A 0 . DP=16;I16=14,1,0,0,627,27579,0,0,838,48482,0,0,256,5514,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,169:7:0 0,9,110:3:0 0,15,151:5:0 +17 133 . T 0 . DP=15;I16=13,2,0,0,584,22816,0,0,838,48482,0,0,282,6196,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,163:7:0 0,9,105:3:0 0,15,150:5:0 +17 134 . C 0 . DP=15;I16=13,2,0,0,607,24653,0,0,838,48482,0,0,283,6267,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,177:7:0 0,9,105:3:0 0,15,152:5:0 +17 135 . T 0 . DP=15;I16=13,2,0,0,600,24178,0,0,838,48482,0,0,284,6352,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,173:7:0 0,9,106:3:0 0,15,156:5:0 +17 136 . G 0 . DP=15;I16=13,2,0,0,574,22258,0,0,838,48482,0,0,286,6450,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,172:7:0 0,9,105:3:0 0,15,134:5:0 +17 137 . T 0 . DP=15;I16=13,2,0,0,563,21377,0,0,838,48482,0,0,289,6561,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,160:7:0 0,9,104:3:0 0,15,139:5:0 +17 138 . C 0 . DP=15;I16=13,2,0,0,584,23088,0,0,838,48482,0,0,291,6637,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,172:7:0 0,9,108:3:0 0,15,142:5:0 +17 139 . C 0 . DP=15;I16=13,2,0,0,554,20790,0,0,838,48482,0,0,292,6680,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,161:7:0 0,9,106:3:0 0,15,143:5:0 +17 140 . A 0 . DP=15;I16=13,2,0,0,583,22789,0,0,838,48482,0,0,292,6690,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,163:7:0 0,9,107:3:0 0,15,153:5:0 +17 141 . G 0 . DP=14;I16=12,2,0,0,534,20750,0,0,778,44882,0,0,292,6664,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,158:6:0 0,9,108:3:0 0,15,142:5:0 +17 142 . C 0 . DP=14;I16=12,2,0,0,503,18593,0,0,778,44882,0,0,292,6650,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,157:6:0 0,9,97:3:0 0,15,129:5:0 +17 143 . G 0 . DP=14;I16=11,2,0,0,415,13657,0,0,718,41282,0,0,285,6599,0,0;QS=3,0;MQSB=0.590909;MQ0F=0 PL:DP:DV 0,18,128:6:0 0,9,95:3:0 0,12,97:4:0 +17 144 . A 0 . DP=14;I16=12,2,0,0,519,19725,0,0,778,44882,0,0,291,6609,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,152:6:0 0,9,105:3:0 0,15,129:5:0 +17 145 . A 0 . DP=14;I16=12,2,0,0,527,20289,0,0,778,44882,0,0,290,6584,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,153:6:0 0,9,106:3:0 0,15,138:5:0 +17 146 . T 0 . DP=14;I16=12,2,0,0,514,19484,0,0,778,44882,0,0,289,6573,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,152:6:0 0,9,103:3:0 0,15,128:5:0 +17 147 . A 0 . DP=14;I16=12,2,0,0,515,19213,0,0,778,44882,0,0,288,6576,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,150:6:0 0,9,99:3:0 0,15,140:5:0 +17 148 . C 0 . DP=14;I16=12,2,0,0,541,21019,0,0,778,44882,0,0,286,6542,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,157:6:0 0,9,106:3:0 0,15,146:5:0 +17 149 . C 0 . DP=14;I16=12,2,0,0,512,19326,0,0,778,44882,0,0,283,6471,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,148:6:0 0,9,109:3:0 0,15,140:5:0 +17 150 . T 0 . DP=13;I16=11,2,0,0,511,20251,0,0,749,44041,0,0,280,6362,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,153:6:0 0,6,84:2:0 0,15,152:5:0 +17 151 . G 0 . DP=13;I16=11,2,0,0,506,19826,0,0,749,44041,0,0,277,6263,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,157:6:0 0,6,84:2:0 0,15,144:5:0 +17 152 . C 0 . DP=14;I16=12,2,0,0,543,21283,0,0,809,47641,0,0,274,6174,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,168:7:0 0,6,84:2:0 0,15,146:5:0 +17 153 . A 0 . DP=14;I16=12,2,0,0,536,20594,0,0,809,47641,0,0,272,6096,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,156:7:0 0,6,81:2:0 0,15,153:5:0 +17 154 . T 0 . DP=14;I16=12,2,0,0,523,20051,0,0,809,47641,0,0,270,6030,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,159:7:0 0,6,83:2:0 0,15,139:5:0 +17 155 . C 0 . DP=14;I16=12,2,0,0,542,21254,0,0,809,47641,0,0,268,5976,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,172:7:0 0,6,85:2:0 0,15,139:5:0 +17 156 . C 0 . DP=14;I16=12,2,0,0,536,20884,0,0,809,47641,0,0,266,5934,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,163:7:0 0,6,84:2:0 0,15,150:5:0 +17 157 . C 0 . DP=14;I16=12,2,0,0,555,22081,0,0,809,47641,0,0,264,5904,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,169:7:0 0,6,85:2:0 0,15,149:5:0 +17 158 . T 0 . DP=14;I16=12,2,0,0,568,23154,0,0,809,47641,0,0,262,5886,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,170:7:0 0,6,84:2:0 0,15,159:5:0 +17 159 . A 0 . DP=15;I16=12,2,0,0,519,19467,0,0,809,47641,0,0,260,5880,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,157:7:0 0,6,83:2:0 0,15,135:5:0 +17 160 . G 0 . DP=15;I16=13,2,0,0,547,20633,0,0,869,51241,0,0,259,5887,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,165:7:0 0,6,85:2:0 0,18,139:6:0 +17 161 . A 0 . DP=15;I16=13,2,0,0,568,21610,0,0,869,51241,0,0,258,5908,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,157:7:0 0,6,83:2:0 0,18,162:6:0 +17 162 . A 0 . DP=15;I16=13,2,0,0,557,21139,0,0,869,51241,0,0,255,5843,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,147:7:0 0,6,87:2:0 0,18,167:6:0 +17 163 . G 0 . DP=14;I16=12,2,0,0,503,18645,0,0,809,47641,0,0,253,5791,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,153:7:0 0,6,79:2:0 0,15,138:5:0 +17 164 . T 0 . DP=14;I16=12,2,0,0,460,15968,0,0,809,47641,0,0,252,5750,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,131:6:0 0,6,79:2:0 0,18,136:6:0 +17 165 . G 0 . DP=14;I16=10,2,0,0,456,17460,0,0,689,40441,0,0,226,5094,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,149:6:0 0,6,80:2:0 0,12,122:4:0 +17 166 . A 0 . DP=14;I16=11,2,0,0,496,19138,0,0,749,44041,0,0,227,5077,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,145:6:0 0,6,82:2:0 0,15,148:5:0 +17 167 . A 0 . DP=14;I16=11,2,0,0,477,17851,0,0,749,44041,0,0,227,5071,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,132:6:0 0,6,86:2:0 0,15,147:5:0 +17 168 . G 0 . DP=14;I16=12,2,0,0,481,18015,0,0,809,47641,0,0,252,5702,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,145:6:0 0,6,82:2:0 0,18,140:6:0 +17 169 . C 0 . DP=13;I16=10,2,0,0,402,14224,0,0,689,40441,0,0,227,5045,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,15,106:5:0 0,6,76:2:0 0,15,145:5:0 +17 170 . C 0 . DP=13;I16=11,2,0,0,447,16383,0,0,749,44041,0,0,251,5601,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,15,128:5:0 0,6,80:2:0 0,18,143:6:0 +17 171 . A 0 . DP=13;I16=11,2,0,0,500,19366,0,0,749,44041,0,0,250,5546,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,15,134:5:0 0,6,81:2:0 0,18,166:6:0 +17 172 . C 0 . DP=13;I16=10,2,0,0,439,16395,0,0,689,40441,0,0,241,5441,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,15,138:5:0 0,6,75:2:0 0,15,129:5:0 +17 173 . C 0 . DP=13;I16=11,2,0,0,435,15225,0,0,749,44041,0,0,248,5478,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,15,121:5:0 0,6,76:2:0 0,18,146:6:0 +17 174 . G 0 . DP=13;I16=11,1,0,0,351,10685,0,0,689,40441,0,0,238,5364,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,111:5:0 0,3,27:1:0 0,18,117:6:0 +17 175 . C 0 . DP=14;I16=13,1,0,0,511,19161,0,0,809,47641,0,0,249,5463,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,143:6:0 0,3,41:1:0 0,21,175:7:0 +17 176 . C 0 . DP=14;I16=13,1,0,0,489,17733,0,0,809,47641,0,0,251,5477,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,146:6:0 0,3,44:1:0 0,21,152:7:0 +17 177 . C 0 . DP=14;I16=13,1,0,0,488,17328,0,0,809,47641,0,0,253,5507,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,138:6:0 0,3,44:1:0 0,21,158:7:0 +17 178 . A 0 . DP=14;I16=13,1,0,0,519,19485,0,0,809,47641,0,0,254,5502,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,147:6:0 0,3,42:1:0 0,21,172:7:0 +17 179 . A 0 . DP=14;I16=13,1,0,0,478,17278,0,0,809,47641,0,0,255,5511,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,134:6:0 0,3,44:1:0 0,21,170:7:0 +17 180 . A 0 . DP=14;I16=12,1,0,0,425,14653,0,0,749,44041,0,0,250,5498,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,126:6:0 0,3,43:1:0 0,18,148:6:0 +17 181 . G 0 . DP=14;I16=11,1,0,0,450,17152,0,0,689,40441,0,0,233,5233,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,156:6:0 0,3,41:1:0 0,15,138:5:0 +17 182 . A 0 . DP=15;I16=14,1,0,0,515,18235,0,0,869,51241,0,0,258,5622,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,150:7:0 0,3,43:1:0 0,21,159:7:0 +17 183 . C 0 . DP=15;I16=13,1,0,0,483,17419,0,0,809,47641,0,0,235,5063,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,159:7:0 0,3,40:1:0 0,18,139:6:0 +17 184 . A 0 . DP=15;I16=14,1,0,0,535,19667,0,0,869,51241,0,0,262,5770,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,158:7:0 0,3,41:1:0 0,21,163:7:0 +17 185 . C 0 . DP=15;I16=13,1,0,0,487,17295,0,0,809,47641,0,0,238,5192,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,150:7:0 0,3,38:1:0 0,18,160:6:0 +17 186 . G 0 . DP=15;I16=12,1,0,0,381,11429,0,0,749,44041,0,0,239,5253,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,117:6:0 0,3,32:1:0 0,18,124:6:0 +17 187 . C 0 . DP=14;I16=13,1,0,0,511,18979,0,0,809,47641,0,0,266,5952,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,147:6:0 0,3,38:1:0 0,21,172:7:0 +17 188 . C 0 . DP=14;I16=13,1,0,0,496,18042,0,0,809,47641,0,0,267,5989,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,147:6:0 0,3,37:1:0 0,21,162:7:0 +17 189 . C 0 . DP=15;I16=13,2,0,0,552,20504,0,0,838,48482,0,0,268,6040,0,0;QS=3,0;MQSB=0;MQ0F=0 PL:DP:DV 0,18,152:6:0 0,6,67:2:0 0,21,167:7:0 +17 190 . A 0 . DP=15;I16=12,2,0,0,500,18230,0,0,778,44882,0,0,243,5381,0,0;QS=3,0;MQSB=0;MQ0F=0 PL:DP:DV 0,18,138:6:0 0,6,68:2:0 0,18,159:6:0 +17 191 . T 0 . DP=15;I16=13,2,0,0,534,19276,0,0,838,48482,0,0,267,5939,0,0;QS=3,0;MQSB=0;MQ0F=0 PL:DP:DV 0,18,143:6:0 0,6,67:2:0 0,21,169:7:0 +17 192 . G 0 . DP=15;I16=13,2,0,0,499,17439,0,0,838,48482,0,0,266,5890,0,0;QS=3,0;MQSB=0;MQ0F=0 PL:DP:DV 0,18,143:6:0 0,6,67:2:0 0,21,151:7:0 +17 193 . T 0 . DP=15;I16=13,2,0,0,505,17811,0,0,838,48482,0,0,265,5859,0,0;QS=3,0;MQSB=0;MQ0F=0 PL:DP:DV 0,18,140:6:0 0,6,63:2:0 0,21,157:7:0 +17 194 . C 0 . DP=14;I16=12,2,0,0,467,16569,0,0,778,44882,0,0,265,5845,0,0;QS=3,0;MQSB=0;MQ0F=0 PL:DP:DV 0,18,142:6:0 0,6,67:2:0 0,18,145:6:0 +17 195 . C 0 . DP=14;I16=11,3,0,0,503,18647,0,0,747,42123,0,0,266,5846,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,18,159:6:0 0,6,71:2:0 0,18,160:6:0 +17 196 . A 0 . DP=14;I16=11,3,0,0,482,17400,0,0,747,42123,0,0,268,5862,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,18,166:6:0 0,6,69:2:0 0,18,138:6:0 +17 197 . G 0 . DP=14;I16=11,3,0,0,481,17391,0,0,747,42123,0,0,270,5894,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,18,164:6:0 0,6,68:2:0 0,18,134:6:0 +17 198 . C 0 . DP=14;I16=11,3,0,0,539,20957,0,0,747,42123,0,0,271,5893,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,18,172:6:0 0,6,70:2:0 0,18,164:6:0 +17 199 . T 0 . DP=14;I16=11,3,0,0,505,19197,0,0,747,42123,0,0,271,5861,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,18,162:6:0 0,6,73:2:0 0,18,154:6:0 +17 200 . T 0 . DP=15;I16=11,4,0,0,544,19918,0,0,776,42964,0,0,270,5798,0,0;QS=3,0;MQSB=0.0161635;MQ0F=0 PL:DP:DV 0,18,161:6:0 0,9,89:3:0 0,18,154:6:0 +17 201 . A 0 . DP=16;I16=12,4,0,0,568,20416,0,0,836,46564,0,0,269,5703,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,171:7:0 0,9,89:3:0 0,18,157:6:0 +17 202 . A 0 . DP=16;I16=12,4,0,0,566,20590,0,0,836,46564,0,0,269,5627,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,178:7:0 0,9,84:3:0 0,18,163:6:0 +17 203 . C 0 . DP=16;I16=12,4,0,0,557,20119,0,0,836,46564,0,0,269,5571,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,166:7:0 0,9,90:3:0 0,18,153:6:0 +17 204 . C 0 . DP=16;I16=12,4,0,0,591,22379,0,0,836,46564,0,0,269,5535,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,173:7:0 0,9,91:3:0 0,18,163:6:0 +17 205 . T 0 . DP=16;I16=12,4,0,0,635,25281,0,0,836,46564,0,0,269,5519,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,188:7:0 0,9,95:3:0 0,18,173:6:0 +17 206 . G 0 . DP=16;I16=12,4,0,0,577,21337,0,0,836,46564,0,0,269,5523,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,180:7:0 0,9,89:3:0 0,18,143:6:0 +17 207 . C 0 . DP=16;I16=12,4,0,0,574,21076,0,0,836,46564,0,0,269,5547,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,179:7:0 0,9,93:3:0 0,18,151:6:0 +17 208 . A 0 . DP=16;I16=12,4,0,0,576,21486,0,0,836,46564,0,0,268,5540,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,184:7:0 0,9,93:3:0 0,18,154:6:0 +17 209 . T 0 . DP=16;I16=12,4,0,0,567,20475,0,0,836,46564,0,0,267,5551,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,173:7:0 0,9,91:3:0 0,18,146:6:0 +17 210 . C 0 . DP=16;I16=12,4,0,0,577,21109,0,0,836,46564,0,0,266,5580,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,185:7:0 0,9,92:3:0 0,18,151:6:0 +17 211 . C 0 . DP=16;I16=12,4,0,0,563,20227,0,0,836,46564,0,0,265,5627,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,172:7:0 0,9,92:3:0 0,18,153:6:0 +17 212 . C 0 . DP=16;I16=12,4,0,0,589,22179,0,0,836,46564,0,0,263,5643,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,181:7:0 0,9,92:3:0 0,18,152:6:0 +17 213 . T 0 . DP=16;I16=12,4,0,0,598,22838,0,0,836,46564,0,0,262,5678,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,181:7:0 0,9,95:3:0 0,18,165:6:0 +17 214 . A 0 . DP=16;I16=11,4,0,0,529,19401,0,0,776,42964,0,0,240,5248,0,0;QS=3,0;MQSB=0.0161635;MQ0F=0 PL:DP:DV 0,21,176:7:0 0,9,92:3:0 0,15,118:5:0 +17 215 . G 0 . DP=15;I16=12,3,0,0,521,19073,0,0,807,45723,0,0,262,5754,0,0;QS=3,0;MQSB=0.0342181;MQ0F=0 PL:DP:DV 0,21,185:7:0 0,9,90:3:0 0,15,105:5:0 +17 216 . A 0 . DP=14;I16=10,3,0,0,464,16900,0,0,687,38523,0,0,238,5166,0,0;QS=3,0;MQSB=0.040184;MQ0F=0 PL:DP:DV 0,21,173:7:0 0,9,92:3:0 0,9,81:3:0 +17 217 . A 0 . DP=14;I16=11,3,0,0,515,19433,0,0,747,42123,0,0,264,5842,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,21,181:7:0 0,9,90:3:0 0,12,97:4:0 +17 218 . G 0 . DP=14;I16=11,3,0,0,507,18957,0,0,747,42123,0,0,265,5907,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,21,178:7:0 0,9,90:3:0 0,12,110:4:0 +17 219 . T 0 . DP=14;I16=11,3,0,0,470,16286,0,0,747,42123,0,0,266,5986,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,21,173:7:0 0,9,88:3:0 0,12,89:4:0 +17 220 . G 0 . DP=14;I16=10,3,0,0,485,18307,0,0,687,38523,0,0,242,5454,0,0;QS=3,0;MQSB=0.040184;MQ0F=0 PL:DP:DV 0,21,188:7:0 0,9,88:3:0 0,9,80:3:0 +17 221 . A 0 . DP=14;I16=11,3,0,0,487,17615,0,0,747,42123,0,0,267,6135,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,21,176:7:0 0,9,88:3:0 0,12,101:4:0 +17 222 . A 0 . DP=14;I16=10,3,0,0,465,17367,0,0,687,38523,0,0,242,5578,0,0;QS=3,0;MQSB=0.040184;MQ0F=0 PL:DP:DV 0,21,186:7:0 0,9,85:3:0 0,9,69:3:0 +17 223 . G 0 . DP=13;I16=9,3,0,0,405,14327,0,0,627,34923,0,0,243,5657,0,0;QS=3,0;MQSB=0.0443614;MQ0F=0 PL:DP:DV 0,18,168:6:0 0,6,53:2:0 0,12,81:4:0 +17 224 . G 0 . DP=12;I16=9,3,0,0,379,12759,0,0,627,34923,0,0,270,6370,0,0;QS=3,0;MQSB=0.0443614;MQ0F=0 PL:DP:DV 0,18,168:6:0 0,6,50:2:0 0,12,70:4:0 +17 225 . C 0 . DP=12;I16=8,3,0,0,382,13896,0,0,567,31323,0,0,261,6345,0,0;QS=3,0;MQSB=0.0497871;MQ0F=0 PL:DP:DV 0,18,165:6:0 0,6,48:2:0 0,9,83:3:0 +17 226 . A 0 . DP=13;I16=8,3,0,0,381,13669,0,0,567,31323,0,0,248,5894,0,0;QS=3,0;MQSB=0.0497871;MQ0F=0 PL:DP:DV 0,18,166:6:0 0,6,53:2:0 0,9,84:3:0 +17 227 . C 0 . DP=13;I16=8,4,0,0,406,14306,0,0,596,32164,0,0,267,6253,0,0;QS=3,0;MQSB=0.0249144;MQ0F=0 PL:DP:DV 0,21,190:7:0 0,6,53:2:0 0,9,73:3:0 +17 228 . C 0 . DP=13;I16=9,4,0,0,417,14381,0,0,656,35764,0,0,292,6884,0,0;QS=3,0;MQSB=0.0211283;MQ0F=0 PL:DP:DV 0,21,187:7:0 0,6,45:2:0 0,12,96:4:0 +17 229 . G 0 . DP=13;I16=9,3,0,0,358,11424,0,0,627,34923,0,0,270,6414,0,0;QS=3,0;MQSB=0.0443614;MQ0F=0 PL:DP:DV 0,18,136:6:0 0,6,53:2:0 0,12,70:4:0 +17 230 . C 0 . DP=13;I16=9,4,0,0,461,16861,0,0,656,35764,0,0,292,6920,0,0;QS=3,0;MQSB=0.0211283;MQ0F=0 PL:DP:DV 0,21,186:7:0 0,6,53:2:0 0,12,100:4:0 +17 231 . C 0 . DP=13;I16=7,4,0,0,414,15832,0,0,536,28564,0,0,247,5925,0,0;QS=3,0;MQSB=0.0401934;MQ0F=0 PL:DP:DV 0,18,184:6:0 0,6,53:2:0 0,9,82:3:0 +17 232 . C 0 . DP=14;I16=9,4,0,0,471,17371,0,0,656,35764,0,0,267,6363,0,0;QS=3,0;MQSB=0.0211283;MQ0F=0 PL:DP:DV 0,21,198:7:0 0,6,53:2:0 0,12,101:4:0 +17 233 . A 0 . DP=14;I16=10,4,0,0,496,18142,0,0,716,39364,0,0,292,6984,0,0;QS=3,0;MQSB=0.0183156;MQ0F=0 PL:DP:DV 0,21,192:7:0 0,6,53:2:0 0,15,119:5:0 +17 234 . A 0 . DP=14;I16=10,4,0,0,502,18390,0,0,716,39364,0,0,292,6988,0,0;QS=3,0;MQSB=0.0183156;MQ0F=0 PL:DP:DV 0,21,185:7:0 0,6,53:2:0 0,15,123:5:0 +17 235 . A 0 . DP=14;I16=9,4,0,0,476,17652,0,0,656,35764,0,0,267,6375,0,0;QS=3,0;MQSB=0.0211283;MQ0F=0 PL:DP:DV 0,21,186:7:0 0,6,53:2:0 0,12,111:4:0 +17 236 . G 0 . DP=15;I16=11,4,0,0,501,17481,0,0,776,42964,0,0,290,6924,0,0;QS=3,0;MQSB=0.0161635;MQ0F=0 PL:DP:DV 0,24,206:8:0 0,6,53:2:0 0,15,103:5:0 +17 237 . A 0 . DP=14;I16=9,4,0,0,465,16877,0,0,656,35764,0,0,266,6282,0,0;QS=3,0;MQSB=0.0211283;MQ0F=0 PL:DP:DV 0,24,206:8:0 0,6,53:2:0 0,9,92:3:0 +17 238 . C 0 . DP=14;I16=10,4,0,0,482,17238,0,0,716,39364,0,0,292,6900,0,0;QS=3,0;MQSB=0.0183156;MQ0F=0 PL:DP:DV 0,24,211:8:0 0,6,53:2:0 0,12,82:4:0 +17 239 . A 0 . DP=15;I16=10,5,0,0,525,19155,0,0,776,42964,0,0,292,6852,0,0;QS=3,0;MQSB=0.0497871;MQ0F=0 PL:DP:DV 0,27,223:9:0 0,6,50:2:0 0,12,108:4:0 +17 240 . C 0 . DP=15;I16=10,5,0,0,512,17930,0,0,776,42964,0,0,292,6764,0,0;QS=3,0;MQSB=0.0497871;MQ0F=0 PL:DP:DV 0,27,220:9:0 0,6,53:2:0 0,12,106:4:0 +17 241 . G 0 . DP=15;I16=9,5,0,0,444,14636,0,0,716,39364,0,0,269,6159,0,0;QS=3,0;MQSB=0.0561348;MQ0F=0 PL:DP:DV 0,27,203:9:0 0,6,53:2:0 0,9,59:3:0 +17 242 . C 0 . DP=15;I16=10,5,0,0,555,21177,0,0,776,42964,0,0,292,6624,0,0;QS=3,0;MQSB=0.0497871;MQ0F=0 PL:DP:DV 0,27,242:9:0 0,6,53:2:0 0,12,94:4:0 +17 243 . C 0 . DP=16;I16=9,5,0,0,523,19737,0,0,716,39364,0,0,284,6508,0,0;QS=3,0;MQSB=0.0561348;MQ0F=0 PL:DP:DV 0,24,220:8:0 0,6,53:2:0 0,12,104:4:0 +17 244 . C 0 . DP=16;I16=10,6,0,0,620,24272,0,0,805,43805,0,0,298,6568,0,0;QS=3,0;MQSB=0.0253122;MQ0F=0 PL:DP:DV 0,27,245:9:0 0,9,72:3:0 0,12,106:4:0 +17 245 . A 0 . DP=17;I16=10,7,0,0,649,24843,0,0,865,47405,0,0,299,6553,0,0;QS=3,0;MQSB=0.0509867;MQ0F=0 PL:DP:DV 0,27,236:9:0 0,12,93:4:0 0,12,115:4:0 +17 246 . T 0 . DP=18;I16=10,8,0,0,649,23833,0,0,894,48246,0,0,301,6553,0,0;QS=3,0;MQSB=0.0286491;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,12,94:4:0 0,12,98:4:0 +17 247 . G 0 . DP=18;I16=10,8,0,0,642,23610,0,0,894,48246,0,0,304,6570,0,0;QS=3,0;MQSB=0.0286491;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,12,83:4:0 0,12,103:4:0 +17 248 . T 0 . DP=18;I16=10,8,0,0,636,22944,0,0,894,48246,0,0,307,6605,0,0;QS=3,0;MQSB=0.0286491;MQ0F=0 PL:DP:DV 0,30,234:10:0 0,12,86:4:0 0,12,114:4:0 +17 249 . C 0 . DP=18;I16=10,8,0,0,656,24846,0,0,894,48246,0,0,310,6658,0,0;QS=3,0;MQSB=0.0286491;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,12,79:4:0 0,12,112:4:0 +17 250 . C 0 . DP=19;I16=10,9,0,0,694,26160,0,0,923,49087,0,0,311,6631,0,0;QS=3,0;MQSB=0.0168512;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,12,89:4:0 0,15,142:5:0 +17 251 . A 0 . DP=19;I16=9,9,0,0,688,26506,0,0,863,45487,0,0,313,6627,0,0;QS=3,0;MQSB=0.0208913;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,12,97:4:0 0,15,148:5:0 +17 252 . G 0 . DP=18;I16=8,9,0,0,641,24631,0,0,803,41887,0,0,304,6502,0,0;QS=3,0;MQSB=0.026526;MQ0F=0 PL:DP:DV 0,27,243:9:0 0,12,91:4:0 0,12,121:4:0 +17 253 . C 0 . DP=19;I16=9,10,0,0,705,26921,0,0,892,46328,0,0,319,6687,0,0;QS=3,0;MQSB=0.0132999;MQ0F=0 PL:DP:DV 0,27,247:9:0 0,12,86:4:0 0,18,155:6:0 +17 254 . T 0 . DP=20;I16=10,9,0,0,719,27517,0,0,892,46328,0,0,314,6670,0,0;QS=3,0;MQSB=0.00482795;MQ0F=0 PL:DP:DV 0,30,254:10:0 0,9,72:3:0 0,18,164:6:0 +17 255 . T 0 . DP=21;I16=11,10,0,0,750,27076,0,0,1012,53528,0,0,328,6840,0,0;QS=3,0;MQSB=0.00822975;MQ0F=0 PL:DP:DV 0,33,241:11:0 0,12,95:4:0 0,18,161:6:0 +17 256 . A 0 . DP=22;I16=11,11,0,0,811,30063,0,0,1049,54897,0,0,334,6956,0,0;QS=3,0;MQSB=0.00507916;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,110:5:0 0,18,166:6:0 +17 257 . T 0 . DP=22;I16=11,11,0,0,814,30420,0,0,1049,54897,0,0,341,7101,0,0;QS=3,0;MQSB=0.00507916;MQ0F=0 PL:DP:DV 0,33,247:11:0 0,15,113:5:0 0,18,168:6:0 +17 258 . T 0 . DP=22;I16=11,11,0,0,791,28943,0,0,1049,54897,0,0,347,7225,0,0;QS=3,0;MQSB=0.00507916;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,15,116:5:0 0,18,155:6:0 +17 259 . C 0 . DP=22;I16=11,10,0,0,785,29809,0,0,1020,54056,0,0,332,6936,0,0;QS=3,0;MQSB=0.00822975;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,90:4:0 0,18,170:6:0 +17 260 . T 0 . DP=21;I16=10,11,0,0,829,32899,0,0,989,51297,0,0,360,7556,0,0;QS=3,0;MQSB=0.00660016;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,118:5:0 0,15,156:5:0 +17 261 . G 0 . DP=21;I16=10,11,0,0,735,27379,0,0,989,51297,0,0,367,7761,0,0;QS=3,0;MQSB=0.00660016;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,15,111:5:0 0,15,122:5:0 +17 262 . C 0 . DP=22;I16=10,12,0,0,806,30278,0,0,1049,54897,0,0,373,7941,0,0;QS=3,0;MQSB=0.0122507;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,99:5:0 0,18,164:6:0 +17 263 . C 0 . DP=22;I16=10,12,0,0,799,29717,0,0,1049,54897,0,0,380,8146,0,0;QS=3,0;MQSB=0.0122507;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,98:5:0 0,18,168:6:0 +17 264 . C 0 . DP=22;I16=10,12,0,0,821,31325,0,0,1049,54897,0,0,386,8326,0,0;QS=3,0;MQSB=0.0122507;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,104:5:0 0,18,172:6:0 +17 265 . A 0 . DP=21;I16=9,12,0,0,800,31906,0,0,989,51297,0,0,390,8380,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,114:5:0 0,15,129:5:0 +17 266 . G 0 . DP=21;I16=9,11,0,0,747,28155,0,0,960,50456,0,0,369,7833,0,0;QS=3,0;MQSB=0.0237479;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,97:4:0 0,15,138:5:0 +17 267 . T 0 . DP=21;I16=9,11,0,0,739,27465,0,0,960,50456,0,0,373,7935,0,0;QS=3,0;MQSB=0.0237479;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,12,101:4:0 0,15,149:5:0 +17 268 . T 0 . DP=21;I16=9,12,0,0,748,27708,0,0,989,51297,0,0,402,8686,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:DV 0,33,238:11:0 0,15,110:5:0 0,15,156:5:0 +17 269 . C 0 . DP=22;I16=9,12,0,0,764,28632,0,0,989,51297,0,0,381,8211,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,91:4:0 0,15,154:5:0 +17 270 . C 0 . DP=22;I16=9,12,0,0,758,28146,0,0,989,51297,0,0,385,8337,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,96:4:0 0,15,143:5:0 +17 271 . T 0 . DP=22;I16=9,13,0,0,847,32935,0,0,1018,52138,0,0,413,9065,0,0;QS=3,0;MQSB=0.0109431;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,113:5:0 0,15,152:5:0 +17 272 . C 0 . DP=22;I16=9,12,0,0,809,31413,0,0,989,51297,0,0,390,8518,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,96:4:0 0,15,149:5:0 +17 273 . T 0 . DP=22;I16=9,12,0,0,798,30664,0,0,989,51297,0,0,392,8620,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,95:4:0 0,15,161:5:0 +17 274 . C 0 . DP=22;I16=9,12,0,0,763,28177,0,0,989,51297,0,0,394,8746,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,101:4:0 0,15,144:5:0 +17 275 . C 0 . DP=20;I16=7,13,0,0,768,29994,0,0,898,44938,0,0,423,9519,0,0;QS=3,0;MQSB=0.0213617;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,114:5:0 0,12,122:4:0 +17 276 . A 0 . DP=20;I16=7,13,0,0,805,32931,0,0,898,44938,0,0,424,9538,0,0;QS=3,0;MQSB=0.0213617;MQ0F=0 PL:DP:DV 0,33,253:11:0 0,15,122:5:0 0,12,124:4:0 +17 277 . G 0 . DP=20;I16=7,13,0,0,764,29732,0,0,898,44938,0,0,425,9579,0,0;QS=3,0;MQSB=0.0213617;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,114:5:0 0,12,121:4:0 +17 278 . A 0 . DP=21;I16=6,14,0,0,722,26452,0,0,867,42179,0,0,415,9521,0,0;QS=3,0;MQSB=0.0246228;MQ0F=0 PL:DP:DV 0,30,238:10:0 0,18,123:6:0 0,12,121:4:0 +17 279 . A 0 . DP=22;I16=7,15,0,0,786,28694,0,0,956,46620,0,0,427,9677,0,0;QS=3,0;MQSB=0.0124927;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,123:6:0 0,12,122:4:0 +17 280 . A 0 . DP=22;I16=7,15,0,0,815,31561,0,0,956,46620,0,0,428,9684,0,0;QS=3,0;MQSB=0.0124927;MQ0F=0 PL:DP:DV 0,36,253:12:0 0,18,130:6:0 0,12,129:4:0 +17 281 . G 0 . DP=22;I16=7,15,0,0,820,31416,0,0,956,46620,0,0,428,9662,0,0;QS=3,0;MQSB=0.0124927;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,122:6:0 0,12,123:4:0 +17 282 . G 0 . DP=22;I16=7,15,0,0,806,30420,0,0,956,46620,0,0,427,9609,0,0;QS=3,0;MQSB=0.0124927;MQ0F=0 PL:DP:DV 0,36,253:12:0 0,18,124:6:0 0,12,119:4:0 +17 283 . C 0 . DP=23;I16=7,15,0,0,827,31785,0,0,956,46620,0,0,426,9574,0,0;QS=3,0;MQSB=0.0124927;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,125:6:0 0,12,122:4:0 +17 284 . T 0 . DP=23;I16=7,16,0,0,901,35479,0,0,1016,50220,0,0,431,9593,0,0;QS=3,0;MQSB=0.0194969;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,126:6:0 0,15,144:5:0 +17 285 . G 0 . DP=23;I16=7,16,0,0,860,32856,0,0,1016,50220,0,0,431,9607,0,0;QS=3,0;MQSB=0.0194969;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,119:6:0 0,15,132:5:0 +17 286 . C 0 . DP=24;I16=8,16,0,0,875,32883,0,0,1076,53820,0,0,431,9641,0,0;QS=3,0;MQSB=0.0132999;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,150:7:0 0,15,134:5:0 +17 287 . A 0 . DP=25;I16=9,16,0,0,895,32957,0,0,1136,57420,0,0,432,9696,0,0;QS=3,0;MQSB=0.00934348;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,178:8:0 0,15,133:5:0 +17 288 . T 0 . DP=25;I16=9,16,0,0,931,35011,0,0,1136,57420,0,0,432,9674,0,0;QS=3,0;MQSB=0.00934348;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,184:8:0 0,15,146:5:0 +17 289 . G 0 . DP=25;I16=9,16,0,0,939,36117,0,0,1136,57420,0,0,432,9676,0,0;QS=3,0;MQSB=0.00934348;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,185:8:0 0,15,136:5:0 +17 290 . G 0 . DP=23;I16=8,15,0,0,805,29157,0,0,1047,52979,0,0,433,9651,0,0;QS=3,0;MQSB=0.0177152;MQ0F=0 PL:DP:DV 0,33,240:11:0 0,21,164:7:0 0,15,126:5:0 +17 291 . T 0 . DP=24;I16=8,15,0,0,840,31616,0,0,1047,52979,0,0,421,9479,0,0;QS=3,0;MQSB=0.0177152;MQ0F=0 PL:DP:DV 0,33,244:11:0 0,21,168:7:0 0,15,136:5:0 +17 292 . T 0 . DP=25;I16=9,16,0,0,888,32274,0,0,1167,60179,0,0,436,9668,0,0;QS=3,0;MQSB=0.0197089;MQ0F=0 PL:DP:DV 0,33,253:11:0 0,24,181:8:0 0,18,156:6:0 +17 293 . G 0 . DP=26;I16=10,15,0,0,934,35232,0,0,1167,60179,0,0,424,9488,0,0;QS=3,0;MQSB=0.0095249;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,196:8:0 0,15,145:5:0 +17 294 . A 0 . DP=26;I16=10,16,0,0,931,33937,0,0,1227,63779,0,0,443,9785,0,0;QS=3,0;MQSB=0.0149748;MQ0F=0 PL:DP:DV 0,36,252:12:0 0,24,201:8:0 0,18,161:6:0 +17 295 . C 0 . DP=25;I16=10,14,0,0,897,33973,0,0,1169,62097,0,0,430,9544,0,0;QS=3,0;MQSB=0.0310726;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,180:7:0 0,18,159:6:0 +17 296 . A 0 . DP=25;I16=10,15,0,0,874,31846,0,0,1198,62938,0,0,451,9905,0,0;QS=3,0;MQSB=0.0213617;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,169:8:0 0,18,169:6:0 +17 297 . C 0 . DP=25;I16=9,15,0,0,901,34305,0,0,1138,59338,0,0,445,9901,0,0;QS=3,0;MQSB=0.0273237;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,174:7:0 0,18,161:6:0 +17 298 . A 0 . DP=26;I16=11,15,0,0,936,34652,0,0,1258,66538,0,0,459,10121,0,0;QS=3,0;MQSB=0.017008;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,184:8:0 0,21,191:7:0 +17 299 . C 0 . DP=27;I16=11,15,0,0,971,36863,0,0,1258,66538,0,0,464,10266,0,0;QS=3,0;MQSB=0.017008;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,193:8:0 0,21,189:7:0 +17 300 . A 0 . DP=27;I16=11,15,0,0,1001,39455,0,0,1258,66538,0,0,469,10437,0,0;QS=3,0;MQSB=0.017008;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,204:8:0 0,21,210:7:0 +17 301 . G 0 . DP=25;I16=10,14,0,0,928,36116,0,0,1169,62097,0,0,476,10632,0,0;QS=3,0;MQSB=0.0310726;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,195:7:0 0,21,196:7:0 +17 302 . T 0 . DP=25;I16=10,14,0,0,879,32885,0,0,1169,62097,0,0,483,10849,0,0;QS=3,0;MQSB=0.0310726;MQ0F=0 PL:DP:DV 0,30,231:10:0 0,21,172:7:0 0,21,202:7:0 +17 302 . T TA 0 . INDEL;IDV=7;IMF=1;DP=25;I16=2,4,8,11,214,7674,793,33369,236,10564,993,55133,109,2229,377,8629;QS=0.511212,2.48879;VDB=0.27613;SGB=-4.22417;MQSB=0.0443614;MQ0F=0 PL:DP:DV 167,0,96:11:6 157,0,9:7:6 201,21,0:7:7 +17 303 . G 0 . DP=25;I16=10,15,0,0,976,38516,0,0,1229,65697,0,0,497,11181,0,0;QS=3,0;MQSB=0.0443614;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,197:7:0 0,21,195:7:0 +17 304 . C 0 . DP=27;I16=11,16,0,0,991,37005,0,0,1318,70138,0,0,503,11359,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,206:8:0 0,24,200:8:0 +17 305 . C 0 . DP=27;I16=11,16,0,0,1057,41761,0,0,1318,70138,0,0,510,11508,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,213:8:0 0,24,211:8:0 +17 306 . T 0 . DP=27;I16=11,16,0,0,1033,40253,0,0,1318,70138,0,0,517,11679,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,207:8:0 0,24,217:8:0 +17 307 . G 0 . DP=27;I16=11,15,0,0,984,37886,0,0,1289,69297,0,0,498,11198,0,0;QS=3,0;MQSB=0.174566;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,189:7:0 0,24,203:8:0 +17 308 . C 0 . DP=27;I16=11,16,0,0,892,30810,0,0,1318,70138,0,0,529,11991,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,178:8:0 0,24,185:8:0 +17 309 . G 0 . DP=27;I16=11,16,0,0,951,34599,0,0,1318,70138,0,0,535,12183,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:DV 0,33,243:11:0 0,24,183:8:0 0,24,205:8:0 +17 310 . A 0 . DP=27;I16=11,16,0,0,1001,38063,0,0,1318,70138,0,0,540,12350,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,200:8:0 0,24,217:8:0 +17 311 . C 0 . DP=27;I16=11,16,0,0,1037,40263,0,0,1318,70138,0,0,544,12492,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,215:8:0 0,24,210:8:0 +17 312 . A 0 . DP=26;I16=10,16,0,0,985,38043,0,0,1258,66538,0,0,549,12657,0,0;QS=3,0;MQSB=0.157183;MQ0F=0 PL:DP:DV 0,30,237:10:0 0,24,215:8:0 0,24,218:8:0 +17 313 . A 0 . DP=26;I16=10,16,0,0,983,37969,0,0,1258,66538,0,0,551,12695,0,0;QS=3,0;MQSB=0.157183;MQ0F=0 PL:DP:DV 0,30,235:10:0 0,24,219:8:0 0,24,215:8:0 +17 314 . A 0 . DP=27;I16=10,17,0,0,1050,41798,0,0,1318,70138,0,0,553,12757,0,0;QS=3,0;MQSB=0.195223;MQ0F=0 PL:DP:DV 0,33,250:11:0 0,24,217:8:0 0,24,227:8:0 +17 315 . G 0 . DP=26;I16=10,16,0,0,1025,40941,0,0,1289,69297,0,0,557,12843,0,0;QS=3,0;MQSB=0.252051;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,24,216:8:0 0,24,225:8:0 +17 316 . C 0 . DP=27;I16=10,15,0,0,983,39393,0,0,1252,67928,0,0,535,12277,0,0;QS=3,0;MQSB=0.312403;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,183:7:0 0,24,224:8:0 +17 317 . T 0 . DP=27;I16=10,16,0,0,1028,41392,0,0,1320,72056,0,0,547,12557,0,0;QS=3,0;MQSB=0.377061;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,230:8:0 0,24,206:8:0 +17 318 . G 0 . DP=27;I16=10,17,0,0,1038,40546,0,0,1349,72897,0,0,570,13018,0,0;QS=3,0;MQSB=0.297797;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,27,235:9:0 0,24,208:8:0 +17 319 . A 0 . DP=27;I16=9,17,0,0,994,38654,0,0,1289,69297,0,0,560,12906,0,0;QS=3,0;MQSB=0.346864;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,27,228:9:0 0,21,185:7:0 +17 320 . A 0 . DP=27;I16=10,17,0,0,1022,39418,0,0,1349,72897,0,0,573,13053,0,0;QS=3,0;MQSB=0.297797;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,27,230:9:0 0,24,211:8:0 +17 321 . T 0 . DP=27;I16=10,17,0,0,1026,39772,0,0,1349,72897,0,0,573,13029,0,0;QS=3,0;MQSB=0.297797;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,27,214:9:0 0,24,218:8:0 +17 322 . G 0 . DP=28;I16=10,18,0,0,1091,43151,0,0,1409,76497,0,0,573,13029,0,0;QS=3,0;MQSB=0.343265;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,27,226:9:0 0,27,223:9:0 +17 323 . C 0 . DP=28;I16=9,18,0,0,1067,42619,0,0,1349,72897,0,0,565,12939,0,0;QS=3,0;MQSB=0.394987;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,27,225:9:0 0,24,198:8:0 +17 324 . T 0 . DP=30;I16=12,18,0,0,1145,44221,0,0,1529,83697,0,0,573,13001,0,0;QS=3,0;MQSB=0.264959;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,27,237:9:0 0,33,255:11:0 +17 325 . A 0 . DP=31;I16=13,18,0,0,1132,42058,0,0,1589,87297,0,0,573,12925,0,0;QS=3,0;MQSB=0.235201;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,208:9:0 0,33,255:11:0 +17 326 . T 0 . DP=31;I16=13,18,0,0,1157,44193,0,0,1589,87297,0,0,574,12878,0,0;QS=3,0;MQSB=0.235201;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,216:9:0 0,33,255:11:0 +17 327 . C 0 . DP=31;I16=13,18,0,0,1147,43895,0,0,1589,87297,0,0,575,12861,0,0;QS=3,0;MQSB=0.235201;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,198:9:0 0,33,255:11:0 +17 328 . A 0 . DP=31;I16=13,18,0,0,1167,44531,0,0,1589,87297,0,0,574,12776,0,0;QS=3,0;MQSB=0.235201;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,226:9:0 0,33,255:11:0 +17 329 . T 0 . DP=31;I16=13,18,0,0,1210,47742,0,0,1589,87297,0,0,572,12676,0,0;QS=3,0;MQSB=0.235201;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,237:9:0 0,33,255:11:0 +17 330 . T 0 . DP=31;I16=13,18,0,0,1185,45839,0,0,1589,87297,0,0,568,12510,0,0;QS=3,0;MQSB=0.235201;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,27,231:9:0 0,33,255:11:0 +17 331 . T 0 . DP=32;I16=14,18,0,0,1154,42510,0,0,1649,90897,0,0,563,12327,0,0;QS=3,0;MQSB=0.210122;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,222:9:0 0,36,255:12:0 +17 332 . A 0 . DP=32;I16=14,18,0,0,1156,42666,0,0,1649,90897,0,0,560,12178,0,0;QS=3,0;MQSB=0.210122;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,214:9:0 0,33,255:11:0 +17 333 . A 0 . DP=32;I16=14,18,0,0,1141,41987,0,0,1649,90897,0,0,558,12064,0,0;QS=3,0;MQSB=0.210122;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,223:9:0 0,33,255:11:0 +17 334 . A 0 . DP=32;I16=14,18,0,0,1162,43328,0,0,1649,90897,0,0,556,11986,0,0;QS=3,0;MQSB=0.210122;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,221:9:0 0,33,255:11:0 +17 335 . A 0 . DP=32;I16=12,18,0,0,1077,40287,0,0,1529,83697,0,0,552,11934,0,0;QS=3,0;MQSB=0.264959;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,27,219:9:0 0,33,251:11:0 +17 336 . A 0 . DP=32;I16=14,17,0,0,1088,39758,0,0,1612,89528,0,0,536,11574,0,0;QS=3,0;MQSB=0.274662;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,211:8:0 0,36,255:12:0 +17 337 . C 0 . DP=32;I16=13,17,0,0,1115,42381,0,0,1552,85928,0,0,531,11565,0,0;QS=3,0;MQSB=0.301511;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,202:8:0 0,36,255:12:0 +17 338 . T 0 . DP=30;I16=14,16,0,0,1191,47979,0,0,1560,86456,0,0,554,11878,0,0;QS=3,0;MQSB=0.242376;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,226:8:0 0,36,255:12:0 +17 339 . C 0 . DP=31;I16=14,17,0,0,1130,43210,0,0,1589,87297,0,0,554,11874,0,0;QS=3,0;MQSB=0.175471;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,185:8:0 0,36,255:12:0 +17 340 . C 0 . DP=31;I16=14,17,0,0,1196,47044,0,0,1589,87297,0,0,554,11852,0,0;QS=3,0;MQSB=0.175471;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,221:8:0 0,36,255:12:0 +17 341 . T 0 . DP=31;I16=14,17,0,0,1227,48995,0,0,1589,87297,0,0,554,11862,0,0;QS=3,0;MQSB=0.175471;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,216:8:0 0,36,255:12:0 +17 342 . T 0 . DP=31;I16=14,17,0,0,1162,43942,0,0,1589,87297,0,0,554,11904,0,0;QS=3,0;MQSB=0.175471;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,210:8:0 0,36,255:12:0 +17 343 . G 0 . DP=32;I16=14,17,0,0,1150,43702,0,0,1620,90056,0,0,550,11962,0,0;QS=3,0;MQSB=0.283511;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,27,218:9:0 0,36,255:12:0 +17 344 . C 0 . DP=32;I16=14,18,0,0,1181,45169,0,0,1649,90897,0,0,554,12036,0,0;QS=3,0;MQSB=0.210122;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,217:9:0 0,36,255:12:0 +17 345 . T 0 . DP=31;I16=14,17,0,0,1205,47259,0,0,1589,87297,0,0,555,12129,0,0;QS=3,0;MQSB=0.175471;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,221:8:0 0,36,255:12:0 +17 346 . G 0 . DP=31;I16=15,16,0,0,1147,43597,0,0,1620,90056,0,0,557,12255,0,0;QS=3,0;MQSB=0.220358;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,212:8:0 0,36,255:12:0 +17 347 . G 0 . DP=31;I16=14,16,0,0,1119,42227,0,0,1560,86456,0,0,545,12189,0,0;QS=3,0;MQSB=0.242376;MQ0F=0 PL:DP:DV 0,30,251:10:0 0,24,207:8:0 0,36,255:12:0 +17 348 . T 0 . DP=32;I16=15,16,0,0,1145,43007,0,0,1620,90056,0,0,546,12300,0,0;QS=3,0;MQSB=0.220358;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,27,228:9:0 0,36,255:12:0 +17 349 . T 0 . DP=32;I16=16,16,0,0,1194,45350,0,0,1680,93656,0,0,565,12731,0,0;QS=3,0;MQSB=0.201402;MQ0F=0 PL:DP:DV 0,33,246:11:0 0,27,230:9:0 0,36,255:12:0 +17 350 . T 0 . DP=31;I16=16,15,0,0,1142,43072,0,0,1651,92815,0,0,567,12837,0,0;QS=3,0;MQSB=0.286505;MQ0F=0 PL:DP:DV 0,33,249:11:0 0,27,230:9:0 0,33,255:11:0 +17 351 . G 0 . DP=31;I16=16,15,0,0,1146,43750,0,0,1651,92815,0,0,568,12920,0,0;QS=3,0;MQSB=0.286505;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,212:9:0 0,33,255:11:0 +17 352 . A 0 . DP=31;I16=16,14,0,0,1150,45520,0,0,1591,89215,0,0,544,12404,0,0;QS=3,0;MQSB=0.242376;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,224:8:0 0,33,255:11:0 +17 353 . G 0 . DP=29;I16=15,14,0,0,1109,43095,0,0,1562,88374,0,0,570,13064,0,0;QS=3,0;MQSB=0.424373;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,27,231:9:0 0,30,255:10:0 +17 354 . A 0 . DP=28;I16=14,14,0,0,1078,42938,0,0,1502,84774,0,0,571,13075,0,0;QS=3,0;MQSB=0.450096;MQ0F=0 PL:DP:DV 0,27,225:9:0 0,27,244:9:0 0,30,255:10:0 +17 355 . G T, 0 . DP=28;I16=14,13,0,1,1001,37907,41,1681,1442,81174,60,3600,547,12487,25,625;QS=2.875,0.125,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.450096;BQB=1;MQ0F=0 PL:DP:DV 14,0,200,38,203,231:9:1 0,27,222,27,222,222:9:0 0,30,255,30,255,255:10:0 +17 356 . G 0 . DP=27;I16=14,13,0,0,993,37481,0,0,1465,83405,0,0,574,13174,0,0;QS=3,0;MQSB=0.580277;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,24,201:8:0 0,30,255:10:0 +17 357 . C 0 . DP=28;I16=14,13,0,0,1021,39471,0,0,1465,83405,0,0,550,12584,0,0;QS=3,0;MQSB=0.580277;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,205:8:0 0,27,251:9:0 +17 358 . A 0 . DP=28;I16=15,13,0,0,1050,40518,0,0,1525,87005,0,0,576,13216,0,0;QS=3,0;MQSB=0.556581;MQ0F=0 PL:DP:DV 0,30,254:10:0 0,24,197:8:0 0,30,255:10:0 +17 359 . G 0 . DP=29;I16=15,13,0,0,1085,42761,0,0,1525,87005,0,0,552,12620,0,0;QS=3,0;MQSB=0.556581;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,187:7:0 0,33,255:11:0 +17 360 . A 0 . DP=29;I16=15,14,0,0,1111,43259,0,0,1585,90605,0,0,579,13297,0,0;QS=3,0;MQSB=0.604224;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,24,220:8:0 0,33,255:11:0 +17 361 . A 0 . DP=29;I16=15,14,0,0,1116,43442,0,0,1585,90605,0,0,579,13273,0,0;QS=3,0;MQSB=0.604224;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,24,219:8:0 0,33,255:11:0 +17 362 . A 0 . DP=29;I16=16,13,0,0,1104,42700,0,0,1585,90605,0,0,580,13272,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,218:8:0 0,30,255:10:0 +17 363 . A 0 . DP=29;I16=16,13,0,0,1087,41437,0,0,1585,90605,0,0,581,13245,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,213:8:0 0,30,255:10:0 +17 364 . T 0 . DP=29;I16=16,13,0,0,1032,37960,0,0,1585,90605,0,0,582,13244,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:DV 0,33,250:11:0 0,24,205:8:0 0,30,255:10:0 +17 365 . G 0 . DP=29;I16=16,13,0,0,1105,43079,0,0,1585,90605,0,0,582,13218,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,211:8:0 0,30,255:10:0 +17 366 . A 0 . DP=29;I16=16,13,0,0,1090,41562,0,0,1585,90605,0,0,581,13167,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,211:8:0 0,30,255:10:0 +17 367 . T 0 . DP=29;I16=16,13,0,0,1055,39149,0,0,1585,90605,0,0,579,13093,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,204:8:0 0,30,255:10:0 +17 368 . A 0 . DP=29;I16=16,13,0,0,1054,39632,0,0,1585,90605,0,0,576,12998,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,208:8:0 0,30,255:10:0 +17 369 . T 0 . DP=28;I16=16,11,0,0,1037,40275,0,0,1496,86164,0,0,548,12256,0,0;QS=3,0;MQSB=0.659218;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,21,196:7:0 0,30,255:10:0 +17 370 . C 0 . DP=28;I16=16,12,0,0,1045,40219,0,0,1556,89764,0,0,570,12790,0,0;QS=3,0;MQSB=0.705296;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,201:8:0 0,30,255:10:0 +17 371 . T 0 . DP=29;I16=16,13,0,0,1155,46591,0,0,1616,93364,0,0,567,12725,0,0;QS=3,0;MQSB=0.744925;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,227:8:0 0,33,255:11:0 +17 372 . C 0 . DP=30;I16=16,14,0,0,1139,44019,0,0,1676,96964,0,0,564,12636,0,0;QS=3,0;MQSB=0.779025;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,215:8:0 0,33,255:11:0 +17 373 . A 0 . DP=30;I16=16,14,0,0,1142,44118,0,0,1676,96964,0,0,561,12525,0,0;QS=3,0;MQSB=0.779025;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,220:8:0 0,33,255:11:0 +17 374 . T 0 . DP=30;I16=16,14,0,0,1098,41180,0,0,1676,96964,0,0,556,12344,0,0;QS=3,0;MQSB=0.779025;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,221:8:0 0,33,255:11:0 +17 375 . A T, 0 . DP=31;I16=17,13,0,1,1138,43798,14,196,1676,96964,60,3600,547,12177,4,16;QS=2.9661,0.0338983,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.763662;BQB=1;MQ0F=0 PL:DP:DV 0,36,255,36,255,255:12:0 0,24,218,24,218,218:8:0 0,18,255,30,255,255:11:1 +17 376 . G 0 . DP=31;I16=17,14,0,0,1131,42581,0,0,1736,100564,0,0,547,12073,0,0;QS=3,0;MQSB=0.763662;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,220:8:0 0,33,255:11:0 +17 377 . T 0 . DP=31;I16=16,14,0,0,1105,41629,0,0,1676,96964,0,0,518,11360,0,0;QS=3,0;MQSB=0.779025;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,211:8:0 0,33,255:11:0 +17 378 . T 0 . DP=30;I16=18,12,0,0,1098,41066,0,0,1707,99723,0,0,541,11927,0,0;QS=3,0;MQSB=0.878946;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,186:7:0 0,30,255:10:0 +17 379 . G 0 . DP=29;I16=18,10,0,0,1053,40181,0,0,1618,95282,0,0,534,11848,0,0;QS=3,0;MQSB=0.981777;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,187:7:0 0,30,255:10:0 +17 380 . C 0 . DP=29;I16=18,10,0,0,1087,42743,0,0,1618,95282,0,0,514,11172,0,0;QS=3,0;MQSB=0.981777;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,177:6:0 0,30,255:10:0 +17 381 . T 0 . DP=29;I16=18,11,0,0,1168,47412,0,0,1678,98882,0,0,537,11729,0,0;QS=3,0;MQSB=0.987702;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,212:7:0 0,30,255:10:0 +17 382 . T 0 . DP=29;I16=17,11,0,0,1054,40450,0,0,1618,95282,0,0,510,11068,0,0;QS=3,0;MQSB=0.990092;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,182:7:0 0,30,255:10:0 +17 383 . T 0 . DP=29;I16=18,10,0,0,1052,39798,0,0,1618,95282,0,0,507,11013,0,0;QS=3,0;MQSB=0.981777;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,165:6:0 0,30,255:10:0 +17 384 . A 0 . DP=31;I16=19,11,0,0,1077,39885,0,0,1738,102482,0,0,504,10988,0,0;QS=3,0;MQSB=0.985292;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,176:7:0 0,30,255:10:0 +17 385 . C 0 . DP=31;I16=19,12,0,0,1118,41180,0,0,1798,106082,0,0,527,11569,0,0;QS=3,0;MQSB=0.989977;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,186:8:0 0,30,255:10:0 +17 386 . T 0 . DP=30;I16=18,12,0,0,1158,45592,0,0,1738,102482,0,0,526,11556,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,191:7:0 0,30,255:10:0 +17 387 . T 0 . DP=30;I16=18,12,0,0,1105,41821,0,0,1738,102482,0,0,525,11573,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,187:7:0 0,30,255:10:0 +17 388 . T 0 . DP=29;I16=17,12,0,0,1089,41577,0,0,1678,98882,0,0,523,11519,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,180:6:0 0,30,255:10:0 +17 389 . G 0 . DP=29;I16=17,12,0,0,1067,40095,0,0,1678,98882,0,0,520,11444,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,171:6:0 0,30,255:10:0 +17 390 . C 0 . DP=29;I16=17,12,0,0,1071,40423,0,0,1678,98882,0,0,517,11399,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,162:6:0 0,30,255:10:0 +17 391 . A 0 . DP=29;I16=18,11,0,0,1091,41603,0,0,1647,96123,0,0,515,11383,0,0;QS=3,0;MQSB=0.995968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,163:6:0 0,30,255:10:0 +17 392 . T 0 . DP=29;I16=18,11,0,0,1046,38838,0,0,1647,96123,0,0,515,11395,0,0;QS=3,0;MQSB=0.995968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,153:5:0 0,33,255:11:0 +17 393 . A 0 . DP=28;I16=17,11,0,0,1014,37582,0,0,1587,92523,0,0,517,11435,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,133:5:0 0,33,255:11:0 +17 394 . T 0 . DP=28;I16=17,11,0,0,1022,38342,0,0,1587,92523,0,0,519,11503,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,141:5:0 0,33,255:11:0 +17 395 . T 0 . DP=28;I16=17,11,0,0,1060,40596,0,0,1587,92523,0,0,521,11599,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,164:5:0 0,33,255:11:0 +17 396 . T 0 . DP=28;I16=17,11,0,0,1032,39228,0,0,1587,92523,0,0,523,11723,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,158:5:0 0,33,255:11:0 +17 397 . T 0 . DP=28;I16=17,11,0,0,1046,39510,0,0,1587,92523,0,0,524,11824,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,149:5:0 0,33,255:11:0 +17 398 . A 0 . DP=28;I16=17,11,0,0,1021,38105,0,0,1587,92523,0,0,524,11850,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,144:5:0 0,30,255:10:0 +17 399 . A 0 . DP=28;I16=17,11,0,0,1015,38469,0,0,1587,92523,0,0,526,11900,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,140:5:0 0,30,255:10:0 +17 400 . A 0 . DP=29;I16=17,12,0,0,1056,39702,0,0,1647,96123,0,0,526,11828,0,0;QS=3,0;MQSB=0.988062;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,159:5:0 0,33,255:11:0 +17 401 . A 0 . DP=29;I16=17,11,0,0,1052,40302,0,0,1587,92523,0,0,501,11113,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,160:5:0 0,30,255:10:0 +17 402 . T 0 . DP=29;I16=17,12,0,0,1082,41232,0,0,1647,96123,0,0,526,11680,0,0;QS=3,0;MQSB=0.988062;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,149:5:0 0,33,255:11:0 +17 403 . T 0 . DP=29;I16=17,12,0,0,1085,40985,0,0,1647,96123,0,0,526,11654,0,0;QS=3,0;MQSB=0.988062;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,148:5:0 0,33,255:11:0 +17 404 . G 0 . DP=29;I16=17,12,0,0,1074,40524,0,0,1647,96123,0,0,525,11609,0,0;QS=3,0;MQSB=0.988062;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,131:5:0 0,33,255:11:0 +17 405 . T 0 . DP=27;I16=16,10,0,0,988,37870,0,0,1498,88082,0,0,519,11543,0,0;QS=3,0;MQSB=0.987578;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,103:3:0 0,30,255:10:0 +17 406 . G 0 . DP=27;I16=16,11,0,0,976,36752,0,0,1558,91682,0,0,527,11601,0,0;QS=3,0;MQSB=0.992419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,125:4:0 0,30,247:10:0 +17 407 . A 0 . DP=27;I16=16,11,0,0,1007,38355,0,0,1558,91682,0,0,526,11538,0,0;QS=3,0;MQSB=0.992419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,125:4:0 0,30,255:10:0 +17 408 . C 0 . DP=28;I16=16,11,0,0,1006,38136,0,0,1558,91682,0,0,521,11489,0,0;QS=3,0;MQSB=0.992419;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,110:3:0 0,30,244:10:0 +17 409 . T 0 . DP=29;I16=17,12,0,0,1100,42734,0,0,1678,98882,0,0,525,11503,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,131:4:0 0,33,255:11:0 +17 410 . T 0 . DP=29;I16=17,12,0,0,1035,38325,0,0,1678,98882,0,0,524,11432,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,125:4:0 0,33,255:11:0 +17 411 . T 0 . DP=29;I16=17,10,0,0,1003,37747,0,0,1558,91682,0,0,496,10716,0,0;QS=3,0;MQSB=0.984677;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,104:3:0 0,30,255:10:0 +17 412 . C T, 0 . DP=30;I16=17,12,1,0,1094,42458,14,196,1678,98882,60,3600,495,10659,25,625;QS=2.97455,0.0254545,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.991968;BQB=1;MQ0F=0 PL:DP:DV 0,30,255,42,255,255:15:1 0,12,124,12,124,124:4:0 0,33,255,33,255,255:11:0 +17 413 . A 0 . DP=31;I16=18,13,0,0,1189,45985,0,0,1798,106082,0,0,520,11258,0,0;QS=3,0;MQSB=0.995005;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,102:3:0 0,33,255:11:0 +17 414 . T 0 . DP=30;I16=18,12,0,0,1151,44355,0,0,1738,102482,0,0,523,11265,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,109:3:0 0,33,255:11:0 +17 415 . G 0 . DP=30;I16=18,12,0,0,1131,43175,0,0,1738,102482,0,0,526,11306,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,110:3:0 0,33,255:11:0 +17 416 . G 0 . DP=30;I16=17,12,0,0,1083,41273,0,0,1678,98882,0,0,514,11156,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,114:3:0 0,30,253:10:0 +17 417 . C 0 . DP=30;I16=18,12,0,0,1114,42244,0,0,1738,102482,0,0,531,11439,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,108:3:0 0,33,255:11:0 +17 418 . A 0 . DP=30;I16=18,12,0,0,1146,44248,0,0,1738,102482,0,0,532,11478,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,111:3:0 0,33,255:11:0 +17 419 . T 0 . DP=30;I16=18,12,0,0,1117,42327,0,0,1738,102482,0,0,532,11498,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,112:3:0 0,33,255:11:0 +17 420 . A 0 . DP=31;I16=18,13,0,0,1117,41011,0,0,1798,106082,0,0,532,11550,0,0;QS=3,0;MQSB=0.995005;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,108:3:0 0,36,255:12:0 +17 421 . A 0 . DP=33;I16=19,14,0,0,1208,45398,0,0,1887,110523,0,0,533,11635,0,0;QS=3,0;MQSB=0.986656;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,113:3:0 0,42,255:14:0 +17 422 . A 0 . DP=33;I16=19,13,0,0,1205,46441,0,0,1827,106923,0,0,510,11082,0,0;QS=3,0;MQSB=0.991023;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,116:3:0 0,39,255:13:0 +17 423 . T 0 . DP=32;I16=19,13,0,0,1202,45416,0,0,1827,106923,0,0,538,11818,0,0;QS=3,0;MQSB=0.991023;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,110:3:0 0,39,255:13:0 +17 424 . A 0 . DP=32;I16=19,13,0,0,1147,41685,0,0,1827,106923,0,0,539,11867,0,0;QS=3,0;MQSB=0.991023;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,106:3:0 0,39,255:13:0 +17 425 . A 0 . DP=29;I16=16,13,0,0,1070,40616,0,0,1647,96123,0,0,542,11900,0,0;QS=3,0;MQSB=0.976248;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,111:3:0 0,33,249:11:0 +17 426 . T 0 . DP=29;I16=16,12,0,0,997,36561,0,0,1587,92523,0,0,519,11287,0,0;QS=3,0;MQSB=0.982906;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,105:3:0 0,30,225:10:0 +17 427 . A 0 . DP=29;I16=16,13,0,0,1024,37266,0,0,1647,96123,0,0,546,11952,0,0;QS=3,0;MQSB=0.976248;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,111:3:0 0,33,242:11:0 +17 428 . C 0 . DP=29;I16=16,13,0,0,1064,39706,0,0,1647,96123,0,0,548,12020,0,0;QS=3,0;MQSB=0.976248;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,111:3:0 0,33,254:11:0 +17 429 . T 0 . DP=30;I16=16,14,0,0,1150,44918,0,0,1707,99723,0,0,549,12067,0,0;QS=3,0;MQSB=0.969373;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,115:3:0 0,33,255:11:0 +17 430 . G 0 . DP=30;I16=16,14,0,0,1113,42443,0,0,1707,99723,0,0,551,12145,0,0;QS=3,0;MQSB=0.969373;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,112:3:0 0,33,246:11:0 +17 431 . G 0 . DP=30;I16=14,14,0,0,1003,36953,0,0,1587,92523,0,0,553,12255,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,101:3:0 0,30,225:10:0 +17 432 . T 0 . DP=28;I16=14,14,0,0,1049,39621,0,0,1587,92523,0,0,556,12346,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,114:3:0 0,30,255:10:0 +17 433 . T 0 . DP=28;I16=14,12,0,0,949,35443,0,0,1467,85323,0,0,509,11217,0,0;QS=3,0;MQSB=0.967472;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,112:3:0 0,27,227:9:0 +17 434 . T 0 . DP=29;I16=15,14,0,0,1036,37654,0,0,1647,96123,0,0,561,12567,0,0;QS=3,0;MQSB=0.960561;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,98:3:0 0,30,243:10:0 +17 435 . A 0 . DP=29;I16=15,13,0,0,1024,37970,0,0,1587,92523,0,0,556,12560,0,0;QS=3,0;MQSB=0.968414;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,103:3:0 0,30,237:10:0 +17 436 . T 0 . DP=28;I16=14,14,0,0,998,36220,0,0,1587,92523,0,0,564,12654,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,110:3:0 0,27,223:9:0 +17 437 . T 0 . DP=28;I16=13,14,0,0,990,36832,0,0,1558,91682,0,0,549,12435,0,0;QS=3,0;MQSB=0.999706;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,109:3:0 0,24,207:8:0 +17 438 . A 0 . DP=28;I16=14,13,0,0,972,35640,0,0,1527,88923,0,0,540,12082,0,0;QS=3,0;MQSB=0.9585;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,107:3:0 0,24,216:8:0 +17 439 . C 0 . DP=28;I16=14,14,0,0,1055,40273,0,0,1587,92523,0,0,563,12649,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,107:3:0 0,27,224:9:0 +17 440 . A 0 . DP=28;I16=14,14,0,0,1095,43251,0,0,1587,92523,0,0,561,12615,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,115:3:0 0,27,247:9:0 +17 441 . G 0 . DP=29;I16=15,14,0,0,1068,40344,0,0,1647,96123,0,0,559,12605,0,0;QS=3,0;MQSB=0.960561;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,104:3:0 0,27,198:9:0 +17 442 . A 0 . DP=29;I16=15,14,0,0,1091,41507,0,0,1647,96123,0,0,558,12620,0,0;QS=3,0;MQSB=0.960561;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,112:3:0 0,27,233:9:0 +17 443 . A 0 . DP=30;I16=15,14,0,0,1173,49439,0,0,1647,96123,0,0,557,12661,0,0;QS=3,0;MQSB=0.960561;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,129:3:0 0,27,246:9:0 +17 444 . G 0 . DP=29;I16=15,13,0,0,1095,44661,0,0,1587,92523,0,0,557,12727,0,0;QS=3,0;MQSB=0.968414;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,91:2:0 0,27,227:9:0 +17 445 . C 0 . DP=30;I16=16,13,0,0,1100,43706,0,0,1647,96123,0,0,557,12817,0,0;QS=3,0;MQSB=0.976248;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,111:3:0 0,27,219:9:0 +17 446 . A 0 . DP=30;I16=16,13,0,0,1107,44265,0,0,1647,96123,0,0,557,12881,0,0;QS=3,0;MQSB=0.976248;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,115:3:0 0,27,232:9:0 +17 447 . C 0 . DP=29;I16=16,12,0,0,1108,45364,0,0,1618,95282,0,0,555,12817,0,0;QS=3,0;MQSB=0.856268;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,114:3:0 0,27,235:9:0 +17 448 . T 0 . DP=29;I16=16,12,0,0,1125,47237,0,0,1618,95282,0,0,553,12773,0,0;QS=3,0;MQSB=0.856268;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,118:3:0 0,27,240:9:0 +17 449 . A 0 . DP=28;I16=15,12,0,0,1091,45981,0,0,1558,91682,0,0,552,12748,0,0;QS=3,0;MQSB=0.84246;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,90:2:0 0,27,245:9:0 +17 450 . G 0 . DP=28;I16=15,12,0,0,1069,44603,0,0,1558,91682,0,0,551,12741,0,0;QS=3,0;MQSB=0.84246;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,91:2:0 0,27,233:9:0 +17 451 . A 0 . DP=28;I16=15,12,0,0,1021,41371,0,0,1558,91682,0,0,550,12752,0,0;QS=3,0;MQSB=0.84246;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,93:2:0 0,27,244:9:0 +17 452 . A 0 . DP=31;I16=18,11,0,0,1079,43353,0,0,1678,98882,0,0,530,12420,0,0;QS=3,0;MQSB=0.884952;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,110:3:0 0,24,225:8:0 +17 453 . A 0 . DP=31;I16=17,11,0,0,1037,41069,0,0,1649,98041,0,0,508,11882,0,0;QS=3,0;MQSB=0.967085;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,111:3:0 0,21,221:7:0 +17 454 . A 0 . DP=31;I16=18,12,0,0,1158,47028,0,0,1738,102482,0,0,554,12904,0,0;QS=3,0;MQSB=0.878946;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,113:3:0 0,30,255:10:0 +17 455 . T 0 . DP=32;I16=17,13,0,0,1148,46574,0,0,1715,100251,0,0,550,12864,0,0;QS=3,0;MQSB=0.973855;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,113:3:0 0,33,255:11:0 +17 456 . G 0 . DP=32;I16=17,13,0,0,1161,47287,0,0,1746,103010,0,0,534,12296,0,0;QS=3,0;MQSB=0.998031;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,116:3:0 0,30,245:10:0 +17 457 . C 0 . DP=33;I16=19,13,0,0,1218,48642,0,0,1835,107451,0,0,563,12967,0,0;QS=3,0;MQSB=0.985204;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,118:3:0 0,33,255:11:0 +17 458 . A 0 . DP=33;I16=19,13,0,0,1226,49034,0,0,1835,107451,0,0,568,12990,0,0;QS=3,0;MQSB=0.985204;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,111:3:0 0,33,255:11:0 +17 459 . T 0 . DP=33;I16=18,13,0,0,1167,46981,0,0,1775,103851,0,0,565,12945,0,0;QS=3,0;MQSB=0.980167;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,92:2:0 0,33,255:11:0 +17 460 . G 0 . DP=32;I16=19,12,0,0,1219,50105,0,0,1775,103851,0,0,575,12929,0,0;QS=3,0;MQSB=0.989977;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,116:3:0 0,30,255:10:0 +17 461 . T 0 . DP=32;I16=19,12,0,0,1213,49819,0,0,1775,103851,0,0,577,12845,0,0;QS=3,0;MQSB=0.989977;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,115:3:0 0,30,255:10:0 +17 462 . G 0 . DP=32;I16=19,12,0,0,1190,48962,0,0,1775,103851,0,0,580,12792,0,0;QS=3,0;MQSB=0.989977;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,119:4:0 0,30,241:10:0 +17 463 . G 0 . DP=32;I16=19,12,0,0,1114,44214,0,0,1775,103851,0,0,584,12770,0,0;QS=3,0;MQSB=0.989977;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,114:4:0 0,30,221:10:0 +17 464 . A 0 . DP=32;I16=18,11,0,0,1100,43908,0,0,1686,99410,0,0,556,12106,0,0;QS=3,0;MQSB=0.99095;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,133:4:0 0,24,213:8:0 +17 465 . C 0 . DP=33;I16=20,11,0,0,1191,48085,0,0,1775,103851,0,0,586,12786,0,0;QS=3,0;MQSB=0.996597;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,140:5:0 0,27,231:9:0 +17 466 . A 0 . DP=34;I16=21,12,0,0,1293,53311,0,0,1895,111051,0,0,597,12897,0,0;QS=3,0;MQSB=0.995633;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,154:5:0 0,30,255:10:0 +17 467 . A 0 . DP=34;I16=21,11,0,0,1256,51450,0,0,1835,107451,0,0,597,12891,0,0;QS=3,0;MQSB=0.998231;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,157:5:0 0,27,248:9:0 +17 468 . A 0 . DP=35;I16=22,12,0,0,1274,51268,0,0,1955,114651,0,0,604,12904,0,0;QS=3,0;MQSB=0.997406;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,154:5:0 0,30,251:10:0 +17 469 . A 0 . DP=35;I16=22,12,0,0,1285,52989,0,0,1955,114651,0,0,608,12940,0,0;QS=3,0;MQSB=0.997406;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,146:5:0 0,30,255:10:0 +17 470 . G 0 . DP=35;I16=22,12,0,0,1281,51055,0,0,1955,114651,0,0,612,13016,0,0;QS=3,0;MQSB=0.997406;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,148:5:0 0,30,238:10:0 +17 471 . T 0 . DP=36;I16=22,11,0,0,1239,49021,0,0,1918,113282,0,0,599,12825,0,0;QS=3,0;MQSB=0.915545;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,150:5:0 0,27,232:9:0 +17 472 . T 0 . DP=35;I16=21,12,0,0,1245,48915,0,0,1926,113810,0,0,595,12559,0,0;QS=3,0;MQSB=0.988858;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,153:5:0 0,27,237:9:0 +17 473 . G 0 . DP=35;I16=21,12,0,0,1307,53473,0,0,1926,113810,0,0,599,12651,0,0;QS=3,0;MQSB=0.988858;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,141:5:0 0,27,249:9:0 +17 474 . G 0 . DP=36;I16=22,12,0,0,1284,51708,0,0,1986,117410,0,0,602,12734,0,0;QS=3,0;MQSB=0.986937;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,131:5:0 0,30,255:10:0 +17 475 . G 0 . DP=36;I16=23,12,0,0,1311,51609,0,0,2015,118251,0,0,631,13485,0,0;QS=3,0;MQSB=0.998642;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,141:5:0 0,33,252:11:0 +17 476 . A 0 . DP=36;I16=23,12,0,0,1312,52078,0,0,2015,118251,0,0,634,13606,0,0;QS=3,0;MQSB=0.998642;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,157:5:0 0,33,255:11:0 +17 477 . T 0 . DP=36;I16=23,12,0,0,1318,52668,0,0,2015,118251,0,0,637,13773,0,0;QS=3,0;MQSB=0.998642;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,148:5:0 0,33,255:11:0 +17 478 . T 0 . DP=38;I16=25,12,0,0,1338,51774,0,0,2135,125451,0,0,637,13833,0,0;QS=3,0;MQSB=0.999868;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,18,154:6:0 0,33,255:11:0 +17 479 . A 0 . DP=38;I16=25,12,0,0,1420,57788,0,0,2135,125451,0,0,639,13935,0,0;QS=3,0;MQSB=0.999868;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,18,163:6:0 0,33,255:11:0 +17 480 . G 0 . DP=37;I16=25,11,0,0,1438,60172,0,0,2075,121851,0,0,641,14029,0,0;QS=3,0;MQSB=0.999853;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,165:6:0 0,33,255:11:0 +17 481 . G 0 . DP=37;I16=25,11,0,0,1392,55824,0,0,2075,121851,0,0,642,14112,0,0;QS=3,0;MQSB=0.999853;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,165:6:0 0,33,255:11:0 +17 482 . A 0 . DP=37;I16=24,11,0,0,1352,55134,0,0,2015,118251,0,0,618,13608,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,143:5:0 0,33,255:11:0 +17 483 . G 0 . DP=37;I16=24,12,0,0,1417,57747,0,0,2075,121851,0,0,642,14240,0,0;QS=3,0;MQSB=0.999437;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,165:6:0 0,33,255:11:0 +17 484 . A 0 . DP=36;I16=24,11,0,0,1340,53992,0,0,2015,118251,0,0,643,14281,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,168:6:0 0,33,255:11:0 +17 485 . G 0 . DP=35;I16=23,12,0,0,1329,51411,0,0,2015,118251,0,0,669,14931,0,0;QS=3,0;MQSB=0.998642;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,160:6:0 0,33,255:11:0 +17 486 . A 0 . DP=34;I16=22,12,0,0,1311,51523,0,0,1955,114651,0,0,671,14989,0,0;QS=3,0;MQSB=0.997406;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,173:6:0 0,33,255:11:0 +17 487 . G 0 . DP=34;I16=22,12,0,0,1306,50760,0,0,1955,114651,0,0,672,15030,0,0;QS=3,0;MQSB=0.997406;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,169:6:0 0,33,255:11:0 +17 488 . A 0 . DP=35;I16=22,12,0,0,1274,48140,0,0,1986,117410,0,0,646,14380,0,0;QS=3,0;MQSB=0.986937;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,177:6:0 0,30,255:10:0 +17 489 . A 0 . DP=35;I16=23,12,0,0,1264,46916,0,0,2015,118251,0,0,671,15015,0,0;QS=3,0;MQSB=0.998642;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,175:6:0 0,33,255:11:0 +17 490 . A 0 . DP=36;I16=24,12,0,0,1332,50280,0,0,2075,121851,0,0,671,15061,0,0;QS=3,0;MQSB=0.999437;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,188:7:0 0,33,255:11:0 +17 491 . T 0 . DP=36;I16=24,12,0,0,1284,46802,0,0,2075,121851,0,0,671,15093,0,0;QS=3,0;MQSB=0.999437;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,178:7:0 0,33,255:11:0 +17 492 . G 0 . DP=35;I16=21,12,0,0,1252,48326,0,0,1926,113810,0,0,621,13859,0,0;QS=3,0;MQSB=0.988858;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,172:6:0 0,30,251:10:0 +17 493 . A 0 . DP=34;I16=22,11,0,0,1273,49481,0,0,1926,113810,0,0,650,14672,0,0;QS=3,0;MQSB=0.981935;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,186:7:0 0,24,240:8:0 +17 494 . A 0 . DP=34;I16=22,12,0,0,1326,52604,0,0,1986,117410,0,0,672,15182,0,0;QS=3,0;MQSB=0.986937;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,196:7:0 0,27,255:9:0 +17 495 . G 0 . DP=34;I16=21,12,0,0,1255,48577,0,0,1926,113810,0,0,647,14611,0,0;QS=3,0;MQSB=0.988858;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,168:6:0 0,27,244:9:0 +17 496 . A 0 . DP=34;I16=22,12,0,0,1250,46926,0,0,1986,117410,0,0,670,15220,0,0;QS=3,0;MQSB=0.986937;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,186:7:0 0,27,249:9:0 +17 497 . C 0 . DP=34;I16=22,12,0,0,1250,47006,0,0,1986,117410,0,0,665,15087,0,0;QS=3,0;MQSB=0.986937;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,164:7:0 0,27,239:9:0 +17 498 . A 0 . DP=34;I16=22,12,0,0,1286,49158,0,0,1986,117410,0,0,661,14987,0,0;QS=3,0;MQSB=0.986937;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,185:7:0 0,27,252:9:0 +17 499 . T 0 . DP=34;I16=23,11,0,0,1224,45284,0,0,1986,117410,0,0,659,14919,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,183:7:0 0,30,255:10:0 +17 500 . A 0 . DP=34;I16=23,11,0,0,1230,45152,0,0,1986,117410,0,0,657,14833,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,179:7:0 0,30,255:10:0 +17 501 . T 0 . DP=33;I16=23,10,0,0,1241,47167,0,0,1926,113810,0,0,656,14778,0,0;QS=3,0;MQSB=0.972757;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,186:7:0 0,27,241:9:0 +17 502 . G 0 . DP=33;I16=23,10,0,0,1215,45829,0,0,1926,113810,0,0,655,14753,0,0;QS=3,0;MQSB=0.972757;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,183:7:0 0,27,235:9:0 +17 503 . T 0 . DP=34;I16=23,11,0,0,1194,43366,0,0,1986,117410,0,0,654,14758,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,177:7:0 0,27,234:9:0 +17 504 . C 0 . DP=34;I16=23,11,0,0,1218,45552,0,0,1986,117410,0,0,651,14643,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,183:7:0 0,27,219:9:0 +17 505 . C 0 . DP=35;I16=23,11,0,0,1207,44321,0,0,1986,117410,0,0,641,14509,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,189:7:0 0,27,221:9:0 +17 506 . A 0 . DP=35;I16=24,11,0,0,1266,46776,0,0,2046,121010,0,0,646,14504,0,0;QS=3,0;MQSB=0.977529;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,188:7:0 0,27,231:9:0 +17 507 . C 0 . DP=35;I16=23,11,0,0,1220,45016,0,0,1986,117410,0,0,635,14401,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,183:7:0 0,27,226:9:0 +17 508 . A 0 . DP=34;I16=24,10,0,0,1204,44542,0,0,1986,117410,0,0,643,14491,0,0;QS=3,0;MQSB=0.970272;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,189:7:0 0,27,220:9:0 +17 509 . C 0 . DP=34;I16=24,10,0,0,1272,48272,0,0,1986,117410,0,0,640,14430,0,0;QS=3,0;MQSB=0.970272;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,186:7:0 0,27,241:9:0 +17 510 . A 0 . DP=34;I16=22,11,0,0,1194,44196,0,0,1926,113810,0,0,613,13773,0,0;QS=3,0;MQSB=0.981935;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,187:7:0 0,24,221:8:0 +17 511 . A 0 . DP=34;I16=23,11,0,0,1222,45562,0,0,1986,117410,0,0,637,14395,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,195:7:0 0,24,233:8:0 +17 512 . A C, 0 . DP=33;I16=22,10,0,1,1121,40793,13,169,1866,110210,60,3600,628,14340,9,81;QS=2.97719,0.022807,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.981935;BQB=1;MQ0F=0 PL:DP:DV 0,39,255,51,255,255:18:1 0,21,183,21,183,183:7:0 0,24,231,24,231,231:8:0 +17 513 . A 0 . DP=32;I16=20,10,0,0,1115,42183,0,0,1746,103010,0,0,598,13624,0,0;QS=3,0;MQSB=0.980594;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,175:6:0 0,24,233:8:0 +17 514 . A T, 0 . DP=32;I16=20,9,0,1,1066,40004,16,256,1686,99410,60,3600,586,13500,11,121;QS=2.97075,0.0292505,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.980594;BQB=1;MQ0F=0 PL:DP:DV 0,31,255,45,255,255:16:1 0,18,171,18,171,171:6:0 0,24,235,24,235,235:8:0 +17 515 . C 0 . DP=32;I16=18,10,0,0,1010,37294,0,0,1626,95810,0,0,561,12915,0,0;QS=3,0;MQSB=0.986018;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,167:6:0 0,24,211:8:0 +17 516 . C 0 . DP=32;I16=21,10,0,0,1100,40570,0,0,1806,106610,0,0,612,13954,0,0;QS=3,0;MQSB=0.977926;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,187:7:0 0,24,215:8:0 +17 517 . T 0 . DP=33;I16=23,10,0,0,1269,49995,0,0,1926,113810,0,0,636,14626,0,0;QS=3,0;MQSB=0.972757;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,201:7:0 0,24,242:8:0 +17 518 . G 0 . DP=34;I16=24,10,0,0,1247,46839,0,0,1986,117410,0,0,636,14696,0,0;QS=3,0;MQSB=0.970272;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,182:7:0 0,24,220:8:0 +17 519 . T 0 . DP=36;I16=25,11,0,0,1283,46693,0,0,2106,124610,0,0,636,14742,0,0;QS=3,0;MQSB=0.975394;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,21,177:7:0 0,24,224:8:0 +17 520 . T 0 . DP=36;I16=24,11,0,0,1238,44894,0,0,2046,121010,0,0,613,14193,0,0;QS=3,0;MQSB=0.977529;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,180:7:0 0,24,223:8:0 +17 521 . C 0 . DP=34;I16=25,9,0,0,1280,49454,0,0,1986,117410,0,0,641,14875,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,191:7:0 0,21,204:7:0 +17 522 . A 0 . DP=32;I16=24,8,0,0,1158,43228,0,0,1897,112969,0,0,646,14960,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,185:7:0 0,15,170:5:0 +17 523 . T G, 0 . DP=32;I16=23,8,1,0,1184,45708,15,225,1837,109369,60,3600,626,14446,25,625;QS=2.9794,0.0206044,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.872525;BQB=1;MQ0F=0 PL:DP:DV 0,44,255,57,255,255:20:1 0,21,191,21,191,191:7:0 0,15,166,15,166,166:5:0 +17 524 . T 0 . DP=32;I16=24,7,0,0,1084,39474,0,0,1837,109369,0,0,629,14483,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,194:7:0 0,12,140:4:0 +17 525 . G 0 . DP=32;I16=24,7,0,0,1181,45669,0,0,1837,109369,0,0,631,14495,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,188:7:0 0,12,129:4:0 +17 526 . C 0 . DP=32;I16=24,7,0,0,1146,43950,0,0,1860,111600,0,0,633,14531,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,185:7:0 0,12,131:4:0 +17 527 . A 0 . DP=33;I16=24,8,0,0,1209,46265,0,0,1897,112969,0,0,636,14634,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,194:7:0 0,18,181:6:0 +17 528 . G 0 . DP=33;I16=24,8,0,0,1256,49824,0,0,1897,112969,0,0,634,14484,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,18,169:6:0 0,18,193:6:0 +17 529 . C 0 . DP=32;I16=24,7,0,0,1148,44362,0,0,1837,109369,0,0,633,14357,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,187:7:0 0,18,184:6:0 +17 530 . T 0 . DP=32;I16=25,7,0,0,1244,49168,0,0,1897,112969,0,0,657,14883,0,0;QS=3,0;MQSB=0.850154;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,196:7:0 0,18,202:6:0 +17 531 . T 0 . DP=32;I16=25,7,0,0,1177,44171,0,0,1897,112969,0,0,654,14714,0,0;QS=3,0;MQSB=0.850154;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,181:7:0 0,18,193:6:0 +17 532 . T 0 . DP=32;I16=24,7,0,0,1153,43543,0,0,1837,109369,0,0,630,14116,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,181:7:0 0,18,192:6:0 +17 533 . C 0 . DP=32;I16=24,7,0,0,1142,43940,0,0,1837,109369,0,0,619,13649,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,178:7:0 0,18,180:6:0 +17 534 . T 0 . DP=31;I16=24,6,0,0,1212,49426,0,0,1777,105769,0,0,615,13479,0,0;QS=3,0;MQSB=0.82403;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,205:7:0 0,18,205:6:0 +17 535 . A 0 . DP=31;I16=24,6,0,0,1080,39870,0,0,1777,105769,0,0,611,13341,0,0;QS=3,0;MQSB=0.82403;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,194:7:0 0,18,189:6:0 +17 536 . C 0 . DP=31;I16=24,7,0,0,1097,40707,0,0,1837,109369,0,0,631,13809,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,184:7:0 0,18,157:6:0 +17 537 . C 0 . DP=31;I16=22,7,0,0,1034,38564,0,0,1717,102169,0,0,587,12861,0,0;QS=3,0;MQSB=0.854582;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,172:7:0 0,18,183:6:0 +17 538 . A 0 . DP=31;I16=24,7,0,0,1138,42478,0,0,1837,109369,0,0,620,13536,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,189:7:0 0,18,181:6:0 +17 539 . T 0 . DP=31;I16=24,7,0,0,1134,42070,0,0,1837,109369,0,0,614,13422,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,178:7:0 0,18,181:6:0 +17 540 . C 0 . DP=31;I16=24,7,0,0,1148,43768,0,0,1837,109369,0,0,608,13340,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,177:7:0 0,18,178:6:0 +17 541 . A 0 . DP=32;I16=24,6,0,0,1083,40483,0,0,1777,105769,0,0,551,11991,0,0;QS=3,0;MQSB=0.82403;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,180:8:0 0,15,150:5:0 +17 542 . C 0 . DP=33;I16=25,6,0,0,1123,41759,0,0,1837,109369,0,0,570,12552,0,0;QS=3,0;MQSB=0.822578;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,172:8:0 0,18,174:6:0 +17 543 . C 0 . DP=34;I16=25,9,0,0,1219,45959,0,0,1986,117410,0,0,601,13245,0,0;QS=3,0;MQSB=0.621145;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,27,194:9:0 0,18,188:6:0 +17 544 . A 0 . DP=33;I16=24,8,0,0,1170,43898,0,0,1866,110210,0,0,570,12506,0,0;QS=3,0;MQSB=0.579578;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,192:8:0 0,18,180:6:0 +17 545 . A 0 . DP=33;I16=25,8,0,0,1174,43602,0,0,1926,113810,0,0,587,12951,0,0;QS=3,0;MQSB=0.576102;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,190:8:0 0,18,184:6:0 +17 546 . A 0 . DP=32;I16=24,8,0,0,1126,41444,0,0,1866,110210,0,0,580,12802,0,0;QS=3,0;MQSB=0.579578;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,166:7:0 0,18,193:6:0 +17 547 . A 0 . DP=32;I16=24,7,0,0,1129,42381,0,0,1806,106610,0,0,547,12009,0,0;QS=3,0;MQSB=0.525788;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,180:7:0 0,18,195:6:0 +17 548 . A 0 . DP=33;I16=23,9,0,0,1153,42673,0,0,1866,110210,0,0,561,12489,0,0;QS=3,0;MQSB=0.628357;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,181:7:0 0,21,211:7:0 +17 549 . T G, 0 . DP=32;I16=22,8,0,1,1101,40987,20,400,1746,103010,60,3600,530,11716,25,625;QS=2.96748,0.0325203,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.632337;BQB=1;MQ0F=0 PL:DP:DV 0,31,255,48,255,255:17:1 0,21,168,21,168,168:7:0 0,21,208,21,208,208:7:0 +17 550 . T 0 . DP=32;I16=22,9,0,0,1052,37298,0,0,1806,106610,0,0,548,12176,0,0;QS=3,0;MQSB=0.632337;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,150:7:0 0,21,220:7:0 +17 551 . G 0 . DP=31;I16=22,9,0,0,1121,41639,0,0,1806,106610,0,0,541,12045,0,0;QS=3,0;MQSB=0.632337;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,172:7:0 0,21,208:7:0 +17 552 . C 0 . DP=30;I16=21,9,0,0,1093,41365,0,0,1746,103010,0,0,535,11947,0,0;QS=3,0;MQSB=0.636601;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,167:7:0 0,21,208:7:0 +17 553 . A 0 . DP=30;I16=20,8,0,0,981,35387,0,0,1626,95810,0,0,485,10831,0,0;QS=3,0;MQSB=0.596163;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,150:6:0 0,21,194:7:0 +17 554 . A 0 . DP=30;I16=19,9,0,0,975,35601,0,0,1626,95810,0,0,488,10906,0,0;QS=3,0;MQSB=0.646113;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,139:5:0 0,24,211:8:0 +17 555 . A 0 . DP=30;I16=20,10,0,0,1024,36526,0,0,1746,103010,0,0,514,11392,0,0;QS=3,0;MQSB=0.679025;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,150:6:0 0,21,211:7:0 +17 556 . C 0 . DP=29;I16=20,9,0,0,1055,39195,0,0,1709,101641,0,0,509,11219,0,0;QS=3,0;MQSB=0.894839;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,158:6:0 0,18,186:6:0 +17 557 . A 0 . DP=27;I16=18,9,0,0,987,36749,0,0,1589,94441,0,0,506,11074,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,157:6:0 0,18,186:6:0 +17 558 . A 0 . DP=27;I16=18,8,0,0,948,35808,0,0,1560,93600,0,0,477,10281,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,143:5:0 0,18,177:6:0 +17 559 . C A, 0 . DP=27;I16=17,8,0,1,908,33726,14,196,1500,90000,29,841,448,9516,25,625;QS=2.92708,0.0729167,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.90038;BQB=1;MQ0F=0 PL:DP:DV 0,42,255,42,255,255:14:0 0,4,116,15,119,123:6:1 0,18,169,18,169,169:6:0 +17 560 . C 0 . DP=28;I16=19,9,0,0,992,36552,0,0,1649,98041,0,0,494,10654,0,0;QS=3,0;MQSB=0.896555;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,160:6:0 0,21,181:7:0 +17 561 . A 0 . DP=28;I16=18,9,0,0,963,35455,0,0,1589,94441,0,0,466,9946,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,158:6:0 0,21,194:7:0 +17 562 . C 0 . DP=28;I16=18,9,0,0,1006,38392,0,0,1589,94441,0,0,463,9893,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,153:6:0 0,21,187:7:0 +17 563 . A 0 . DP=27;I16=17,9,0,0,893,32413,0,0,1529,90841,0,0,460,9820,0,0;QS=3,0;MQSB=0.90038;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,149:5:0 0,21,179:7:0 +17 564 . C 0 . DP=27;I16=18,9,0,0,859,28747,0,0,1589,94441,0,0,482,10402,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,121:5:0 0,21,182:7:0 +17 565 . G 0 . DP=30;I16=17,9,0,0,818,26928,0,0,1560,93600,0,0,454,9764,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,96:4:0 0,21,154:7:0 +17 566 . C 0 . DP=29;I16=15,11,0,0,903,33405,0,0,1529,90841,0,0,424,9084,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,155:5:0 0,18,167:6:0 +17 567 . C 0 . DP=30;I16=15,12,0,0,932,33774,0,0,1589,94441,0,0,462,10178,0,0;QS=3,0;MQSB=0.935229;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,155:5:0 0,21,196:7:0 +17 568 . C 0 . DP=29;I16=15,13,0,0,1057,40817,0,0,1649,98041,0,0,482,10438,0,0;QS=3,0;MQSB=0.942064;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,183:6:0 0,18,189:6:0 +17 569 . T 0 . DP=30;I16=16,12,0,0,1056,41296,0,0,1649,98041,0,0,493,10655,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,190:6:0 0,21,213:7:0 +17 570 . T 0 . DP=30;I16=16,12,0,0,954,34972,0,0,1680,100800,0,0,472,10086,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,157:5:0 0,21,195:7:0 +17 571 . C 0 . DP=31;I16=17,12,0,0,1061,40675,0,0,1740,104400,0,0,472,10158,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,155:5:0 0,21,193:7:0 +17 572 . A 0 . DP=31;I16=18,12,0,0,1102,42642,0,0,1769,105241,0,0,499,10887,0,0;QS=3,0;MQSB=0.929991;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,203:7:0 0,18,175:6:0 +17 573 . A 0 . DP=31;I16=18,12,0,0,1057,38473,0,0,1769,105241,0,0,501,10975,0,0;QS=3,0;MQSB=0.929991;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,199:7:0 0,18,178:6:0 +17 574 . C A, 0 . DP=31;I16=18,11,0,1,1088,41328,15,225,1740,104400,29,841,478,10422,25,625;QS=2.94071,0.0592885,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.929991;BQB=1;MQ0F=0 PL:DP:DV 0,48,255,48,255,255:16:0 0,9,170,21,173,177:8:1 0,18,173,18,173,173:6:0 +17 575 . T 0 . DP=30;I16=16,10,0,0,1024,41260,0,0,1560,93600,0,0,448,9842,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,209:7:0 0,15,163:5:0 +17 576 . G 0 . DP=30;I16=17,12,0,0,1047,40077,0,0,1709,101641,0,0,507,11087,0,0;QS=3,0;MQSB=0.931617;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,208:8:0 0,15,151:5:0 +17 577 . G 0 . DP=30;I16=16,12,0,0,999,37747,0,0,1649,98041,0,0,489,10755,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,204:8:0 0,15,146:5:0 +17 578 . G 0 . DP=29;I16=16,13,0,0,975,34803,0,0,1709,101641,0,0,520,11286,0,0;QS=3,0;MQSB=0.940317;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,198:8:0 0,15,151:5:0 +17 579 . G 0 . DP=30;I16=15,13,0,0,1028,38752,0,0,1649,98041,0,0,484,10514,0,0;QS=3,0;MQSB=0.942064;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,224:8:0 0,12,145:4:0 +17 580 . A C, 0 . DP=30;I16=15,14,1,0,1060,39178,16,256,1709,101641,60,3600,510,11078,17,289;QS=2.97338,0.0266223,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.946202;BQB=1;MQ0F=0 PL:DP:DV 0,34,255,48,255,255:17:1 0,24,221,24,221,221:8:0 0,15,155,15,155,155:5:0 +17 581 . A 0 . DP=31;I16=16,15,0,0,1083,39215,0,0,1829,108841,0,0,530,11384,0,0;QS=3,0;MQSB=0.951229;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,223:8:0 0,15,153:5:0 +17 582 . C 0 . DP=31;I16=15,15,0,0,1080,39870,0,0,1769,105241,0,0,519,11211,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,207:8:0 0,15,151:5:0 +17 583 . T 0 . DP=30;I16=16,14,0,0,1136,43996,0,0,1769,105241,0,0,539,11523,0,0;QS=3,0;MQSB=0.946202;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,238:8:0 0,15,163:5:0 +17 584 . C 0 . DP=31;I16=16,13,0,0,1051,39351,0,0,1709,101641,0,0,499,10619,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,207:7:0 0,15,157:5:0 +17 585 . A 0 . DP=31;I16=17,14,0,0,1096,39866,0,0,1798,106082,0,0,549,11751,0,0;QS=3,0;MQSB=0.998229;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,211:8:0 0,15,157:5:0 +17 586 . T 0 . DP=31;I16=16,14,0,0,1081,39839,0,0,1738,102482,0,0,546,11796,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,212:8:0 0,15,156:5:0 +17 587 . C 0 . DP=31;I16=17,13,0,0,1070,39402,0,0,1769,105241,0,0,532,11350,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,201:7:0 0,15,155:5:0 +17 588 . A 0 . DP=31;I16=17,14,0,0,1126,41642,0,0,1798,106082,0,0,562,12140,0,0;QS=3,0;MQSB=0.998229;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,222:8:0 0,15,164:5:0 +17 589 . A 0 . DP=31;I16=17,14,0,0,1157,43973,0,0,1798,106082,0,0,568,12340,0,0;QS=3,0;MQSB=0.998229;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,236:8:0 0,15,165:5:0 +17 590 . C 0 . DP=32;I16=16,14,0,0,1094,41302,0,0,1769,105241,0,0,549,11951,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,192:6:0 0,18,175:6:0 +17 591 . A 0 . DP=31;I16=16,15,0,0,1165,44163,0,0,1798,106082,0,0,579,12695,0,0;QS=3,0;MQSB=0.999805;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,209:7:0 0,18,188:6:0 +17 592 . A 0 . DP=31;I16=15,15,0,0,1114,42144,0,0,1738,102482,0,0,571,12651,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,215:7:0 0,18,182:6:0 +17 593 . C 0 . DP=31;I16=15,14,0,0,1065,39889,0,0,1709,101641,0,0,550,12132,0,0;QS=3,0;MQSB=0.954405;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,191:6:0 0,18,174:6:0 +17 594 . A 0 . DP=33;I16=16,16,0,0,1163,42917,0,0,1858,109682,0,0,572,12672,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,205:7:0 0,24,212:8:0 +17 595 . A 0 . DP=33;I16=17,16,0,0,1130,39996,0,0,1918,113282,0,0,589,12905,0,0;QS=3,0;MQSB=0.999838;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,198:7:0 0,24,213:8:0 +17 596 . A 0 . DP=33;I16=16,16,0,0,1059,37039,0,0,1858,109682,0,0,590,12952,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,169:7:0 0,24,230:8:0 +17 597 . C 0 . DP=33;I16=17,16,0,0,1196,44890,0,0,1918,113282,0,0,592,12990,0,0;QS=3,0;MQSB=0.999838;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,204:7:0 0,24,220:8:0 +17 598 . T 0 . DP=33;I16=16,16,0,0,1214,47104,0,0,1858,109682,0,0,593,13013,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,217:7:0 0,24,239:8:0 +17 599 . T 0 . DP=33;I16=16,17,0,0,1183,43669,0,0,1918,113282,0,0,599,13095,0,0;QS=3,0;MQSB=0.999838;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,197:7:0 0,27,247:9:0 +17 600 . G 0 . DP=32;I16=15,17,0,0,1174,44066,0,0,1858,109682,0,0,601,13145,0,0;QS=3,0;MQSB=0.999287;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,194:7:0 0,24,232:8:0 +17 601 . T 0 . DP=32;I16=15,17,0,0,1114,39954,0,0,1858,109682,0,0,603,13227,0,0;QS=3,0;MQSB=0.999287;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,188:7:0 0,24,235:8:0 +17 602 . G 0 . DP=32;I16=15,15,0,0,1090,40326,0,0,1769,105241,0,0,555,12091,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,185:6:0 0,24,229:8:0 +17 603 . G 0 . DP=31;I16=15,16,0,0,1052,37460,0,0,1798,106082,0,0,607,13437,0,0;QS=3,0;MQSB=0.999805;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,186:7:0 0,24,219:8:0 +17 604 . T 0 . DP=31;I16=14,16,0,0,1009,35893,0,0,1769,105241,0,0,564,12540,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,195:8:0 0,21,212:7:0 +17 605 . T 0 . DP=31;I16=12,15,0,0,1001,37741,0,0,1589,94441,0,0,514,11258,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,200:7:0 0,21,214:7:0 +17 606 . T 0 . DP=31;I16=13,16,0,0,992,35202,0,0,1709,101641,0,0,587,13125,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,189:7:0 0,24,217:8:0 +17 607 . A 0 . DP=31;I16=14,16,0,0,1027,36129,0,0,1738,102482,0,0,607,13577,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,176:7:0 0,24,222:8:0 +17 608 . C 0 . DP=32;I16=15,15,0,0,983,33775,0,0,1769,105241,0,0,564,12564,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,178:7:0 0,27,214:9:0 +17 609 . C 0 . DP=32;I16=14,17,0,0,1074,38220,0,0,1798,106082,0,0,606,13678,0,0;QS=3,0;MQSB=0.998229;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,190:7:0 0,27,238:9:0 +17 610 . C 0 . DP=32;I16=15,16,0,0,1158,44218,0,0,1829,108841,0,0,594,13444,0,0;QS=3,0;MQSB=0.951229;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,211:8:0 0,27,246:9:0 +17 611 . A 0 . DP=32;I16=15,16,0,0,1080,39204,0,0,1798,106082,0,0,590,13260,0,0;QS=3,0;MQSB=0.999805;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,220:9:0 0,27,246:9:0 +17 612 . C 0 . DP=33;I16=16,17,0,0,1175,43305,0,0,1918,113282,0,0,617,13993,0,0;QS=3,0;MQSB=0.999838;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,214:9:0 0,27,250:9:0 +17 613 . A 0 . DP=34;I16=16,17,0,0,1131,40011,0,0,1949,116041,0,0,604,13874,0,0;QS=3,0;MQSB=0.954207;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,223:9:0 0,27,239:9:0 +17 614 . C 0 . DP=34;I16=16,17,0,0,1183,43743,0,0,1949,116041,0,0,608,14022,0,0;QS=3,0;MQSB=0.954207;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,223:9:0 0,27,245:9:0 +17 615 . A 0 . DP=34;I16=16,18,0,0,1199,43809,0,0,1978,116882,0,0,626,14394,0,0;QS=3,0;MQSB=0.999405;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,30,240:10:0 0,27,254:9:0 +17 616 . A 0 . DP=34;I16=16,17,0,0,1190,44024,0,0,1949,116041,0,0,615,14351,0,0;QS=3,0;MQSB=0.954207;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,247:9:0 0,27,255:9:0 +17 617 . T 0 . DP=33;I16=15,18,0,0,1170,43066,0,0,1918,113282,0,0,630,14624,0,0;QS=3,0;MQSB=0.998531;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,30,241:10:0 0,27,255:9:0 +17 618 . G 0 . DP=34;I16=15,19,0,0,1166,41452,0,0,1978,116882,0,0,632,14706,0,0;QS=3,0;MQSB=0.997597;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,30,248:10:0 0,27,240:9:0 +17 619 . G 0 . DP=32;I16=14,18,0,0,1153,42591,0,0,1858,109682,0,0,638,14816,0,0;QS=3,0;MQSB=0.997118;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,30,254:10:0 0,27,247:9:0 +17 620 . A 0 . DP=32;I16=14,17,0,0,1083,39757,0,0,1798,106082,0,0,616,14176,0,0;QS=3,0;MQSB=0.998229;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,30,248:10:0 0,27,255:9:0 +17 621 . A 0 . DP=32;I16=13,18,0,0,1170,45248,0,0,1798,106082,0,0,627,14519,0,0;QS=3,0;MQSB=0.995005;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,255:9:0 0,27,255:9:0 +17 622 . G 0 . DP=32;I16=12,18,0,0,1060,39160,0,0,1769,105241,0,0,604,13888,0,0;QS=3,0;MQSB=0.968257;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,236:9:0 0,27,249:9:0 +17 623 . A T, 0 . DP=32;I16=10,18,1,0,1010,37414,15,225,1649,98041,60,3600,563,12953,25,625;QS=2.96144,0.0385604,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.969907;BQB=1;MQ0F=0 PL:DP:DV 0,20,241,33,244,246:12:1 0,24,213,24,213,213:8:0 0,27,255,27,255,255:9:0 +17 624 . C 0 . DP=32;I16=13,17,0,0,1034,37292,0,0,1738,102482,0,0,607,13887,0,0;QS=3,0;MQSB=0.996503;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,220:9:0 0,27,242:9:0 +17 625 . C 0 . DP=32;I16=13,18,0,0,1108,41138,0,0,1798,106082,0,0,632,14470,0,0;QS=3,0;MQSB=0.995005;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,234:9:0 0,27,249:9:0 +17 626 . A 0 . DP=32;I16=13,17,0,0,1090,40718,0,0,1738,102482,0,0,607,13827,0,0;QS=3,0;MQSB=0.996503;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,237:9:0 0,27,247:9:0 +17 627 . C 0 . DP=32;I16=12,18,0,0,1146,44452,0,0,1769,105241,0,0,607,13833,0,0;QS=3,0;MQSB=0.968257;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,244:9:0 0,27,255:9:0 +17 628 . T 0 . DP=32;I16=11,19,0,0,1124,43114,0,0,1769,105241,0,0,608,13862,0,0;QS=3,0;MQSB=0.972375;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,249:9:0 0,24,249:8:0 +17 629 . T 0 . DP=32;I16=12,19,0,0,1114,41138,0,0,1798,106082,0,0,634,14490,0,0;QS=3,0;MQSB=0.989977;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,247:9:0 0,24,226:8:0 +17 630 . A 0 . DP=31;I16=11,18,0,0,1101,42885,0,0,1740,104400,0,0,610,13844,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,242:8:0 0,24,235:8:0 +17 631 . G 0 . DP=31;I16=12,18,0,0,1083,40525,0,0,1769,105241,0,0,636,14474,0,0;QS=3,0;MQSB=0.929991;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,233:8:0 0,24,223:8:0 +17 632 . C 0 . DP=31;I16=11,18,0,0,1105,42665,0,0,1740,104400,0,0,612,13880,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,233:8:0 0,24,224:8:0 +17 633 . A 0 . DP=31;I16=12,18,0,0,1056,38190,0,0,1769,105241,0,0,638,14562,0,0;QS=3,0;MQSB=0.929991;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,218:8:0 0,24,214:8:0 +17 634 . A 0 . DP=31;I16=12,18,0,0,1110,42208,0,0,1769,105241,0,0,638,14594,0,0;QS=3,0;MQSB=0.929991;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,238:8:0 0,24,229:8:0 +17 635 . C 0 . DP=31;I16=11,18,0,0,1031,37871,0,0,1740,104400,0,0,613,14025,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,220:8:0 0,24,229:8:0 +17 636 . A 0 . DP=31;I16=11,18,0,0,1115,43327,0,0,1740,104400,0,0,611,14005,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,228:8:0 0,24,243:8:0 +17 637 . A 0 . DP=31;I16=12,18,0,0,1152,44602,0,0,1769,105241,0,0,634,14634,0,0;QS=3,0;MQSB=0.929991;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,238:8:0 0,24,242:8:0 +17 638 . A 0 . DP=31;I16=12,18,0,0,1118,42406,0,0,1769,105241,0,0,631,14611,0,0;QS=3,0;MQSB=0.929991;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,235:8:0 0,24,238:8:0 +17 639 . A 0 . DP=30;I16=11,18,0,0,1037,38233,0,0,1709,101641,0,0,602,13934,0,0;QS=3,0;MQSB=0.921439;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,230:8:0 0,24,227:8:0 +17 640 . A 0 . DP=31;I16=11,19,0,0,1154,45368,0,0,1769,105241,0,0,596,13804,0,0;QS=3,0;MQSB=0.91982;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,242:8:0 0,24,240:8:0 +17 641 . G 0 . DP=31;I16=11,19,0,0,1018,36496,0,0,1769,105241,0,0,590,13650,0,0;QS=3,0;MQSB=0.91982;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,214:8:0 0,24,218:8:0 +17 642 . G 0 . DP=30;I16=11,19,0,0,1057,38459,0,0,1769,105241,0,0,610,14148,0,0;QS=3,0;MQSB=0.91982;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,187:7:0 0,24,221:8:0 +17 643 . A 0 . DP=29;I16=11,17,0,0,969,35477,0,0,1649,98041,0,0,585,13605,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,199:7:0 0,24,237:8:0 +17 644 . C A, 0 . DP=29;I16=9,18,1,0,898,30864,17,289,1620,97200,60,3600,549,12567,25,625;QS=2.95685,0.0431472,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,22,236,36,239,243:13:1 0,21,195,21,195,195:7:0 0,24,204,24,204,204:8:0 +17 645 . C 0 . DP=30;I16=10,19,0,0,1067,40337,0,0,1709,101641,0,0,584,13274,0,0;QS=3,0;MQSB=0.909373;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,198:7:0 0,24,226:8:0 +17 646 . A T, 0 . DP=31;I16=9,20,1,0,1044,38174,14,196,1740,104400,60,3600,553,12499,25,625;QS=2.97113,0.028866,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,27,255,39,255,255:14:1 0,21,197,21,197,197:7:0 0,27,229,27,229,229:9:0 +17 647 . A 0 . DP=33;I16=10,21,0,0,1041,35883,0,0,1829,108841,0,0,573,12999,0,0;QS=3,0;MQSB=0.906252;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,189:7:0 0,30,213:10:0 +17 648 . A 0 . DP=33;I16=11,22,0,0,1030,34122,0,0,1949,116041,0,0,594,13478,0,0;QS=3,0;MQSB=0.915545;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,188:7:0 0,30,194:10:0 +17 649 . C 0 . DP=32;I16=10,21,0,0,1099,39879,0,0,1860,111600,0,0,566,12738,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,188:7:0 0,27,217:9:0 +17 650 . T 0 . DP=31;I16=11,18,0,0,1006,37114,0,0,1709,101641,0,0,549,12407,0,0;QS=3,0;MQSB=0.921439;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,187:6:0 0,24,226:8:0 +17 651 . C 0 . DP=32;I16=11,20,0,0,1117,41181,0,0,1829,108841,0,0,581,13107,0,0;QS=3,0;MQSB=0.918304;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,186:6:0 0,27,229:9:0 +17 652 . C 0 . DP=32;I16=9,21,0,0,1126,43084,0,0,1769,105241,0,0,557,12423,0,0;QS=3,0;MQSB=0.893237;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,196:6:0 0,24,213:8:0 +17 653 . T 0 . DP=33;I16=9,23,0,0,1141,42631,0,0,1889,112441,0,0,556,12382,0,0;QS=3,0;MQSB=0.890331;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,198:6:0 0,24,225:8:0 +17 654 . G 0 . DP=33;I16=10,23,0,0,1171,43025,0,0,1949,116041,0,0,578,12798,0,0;QS=3,0;MQSB=0.903508;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,191:6:0 0,24,223:8:0 +17 655 . G 0 . DP=32;I16=10,22,0,0,1118,40202,0,0,1889,112441,0,0,575,12573,0,0;QS=3,0;MQSB=0.904837;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,181:6:0 0,24,213:8:0 +17 656 . T 0 . DP=32;I16=10,22,0,0,1090,38566,0,0,1889,112441,0,0,571,12333,0,0;QS=3,0;MQSB=0.904837;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,185:6:0 0,24,213:8:0 +17 657 . A 0 . DP=32;I16=10,21,0,0,1100,40006,0,0,1829,108841,0,0,557,12029,0,0;QS=3,0;MQSB=0.906252;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,183:6:0 0,24,191:8:0 +17 658 . C 0 . DP=32;I16=10,21,0,0,1115,41039,0,0,1829,108841,0,0,542,11520,0,0;QS=3,0;MQSB=0.906252;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,168:5:0 0,24,211:8:0 +17 659 . A 0 . DP=32;I16=10,21,0,0,1141,42897,0,0,1829,108841,0,0,547,11685,0,0;QS=3,0;MQSB=0.906252;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,191:6:0 0,24,216:8:0 +17 660 . T 0 . DP=33;I16=10,22,0,0,1139,41887,0,0,1889,112441,0,0,553,11659,0,0;QS=3,0;MQSB=0.904837;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,186:6:0 0,24,214:8:0 +17 661 . G 0 . DP=32;I16=9,22,0,0,1107,41531,0,0,1829,108841,0,0,549,11549,0,0;QS=3,0;MQSB=0.891738;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,191:6:0 0,21,188:7:0 +17 662 . C 0 . DP=32;I16=8,22,0,0,1087,40811,0,0,1800,108000,0,0,523,10991,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,192:6:0 0,21,187:7:0 +17 663 . A 0 . DP=32;I16=9,22,0,0,1036,36816,0,0,1829,108841,0,0,540,11388,0,0;QS=3,0;MQSB=0.891738;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,192:6:0 0,21,186:7:0 +17 664 . A 0 . DP=32;I16=9,23,0,0,1125,40759,0,0,1889,112441,0,0,552,11628,0,0;QS=3,0;MQSB=0.890331;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,188:6:0 0,21,184:7:0 +17 665 . C 0 . DP=30;I16=9,21,0,0,1075,39697,0,0,1769,105241,0,0,550,11650,0,0;QS=3,0;MQSB=0.893237;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,186:6:0 0,21,184:7:0 +17 666 . T 0 . DP=29;I16=9,20,0,0,1096,41946,0,0,1709,101641,0,0,547,11607,0,0;QS=3,0;MQSB=0.894839;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,171:5:0 0,21,194:7:0 +17 667 . G 0 . DP=31;I16=11,19,0,0,1037,37627,0,0,1769,105241,0,0,524,11198,0,0;QS=3,0;MQSB=0.91982;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,189:6:0 0,21,188:7:0 +17 668 . A 0 . DP=31;I16=11,20,0,0,1102,39980,0,0,1829,108841,0,0,543,11625,0,0;QS=3,0;MQSB=0.918304;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,190:6:0 0,21,187:7:0 +17 669 . C 0 . DP=30;I16=10,19,0,0,1051,38869,0,0,1740,104400,0,0,528,11464,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,182:6:0 0,21,189:7:0 +17 670 . A 0 . DP=30;I16=11,19,0,0,1121,43423,0,0,1769,105241,0,0,540,11642,0,0;QS=3,0;MQSB=0.91982;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,194:6:0 0,21,205:7:0 +17 671 . G 0 . DP=30;I16=11,19,0,0,1101,41035,0,0,1769,105241,0,0,537,11637,0,0;QS=3,0;MQSB=0.91982;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,181:6:0 0,21,191:7:0 +17 672 . A 0 . DP=30;I16=10,19,0,0,1031,37795,0,0,1740,104400,0,0,521,11479,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,185:6:0 0,21,185:7:0 +17 673 . T 0 . DP=29;I16=8,19,0,0,954,34984,0,0,1589,94441,0,0,497,10885,0,0;QS=3,0;MQSB=0.880529;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,126:4:0 0,21,192:7:0 +17 674 . G 0 . DP=29;I16=10,18,0,0,974,35736,0,0,1649,98041,0,0,497,10827,0,0;QS=3,0;MQSB=0.911099;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,146:5:0 0,21,185:7:0 +17 675 . A 0 . DP=28;I16=9,19,0,0,996,36338,0,0,1649,98041,0,0,517,11389,0,0;QS=3,0;MQSB=0.896555;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,124:4:0 0,21,189:7:0 +17 676 . A 0 . DP=29;I16=8,19,0,0,988,36578,0,0,1589,94441,0,0,462,10106,0,0;QS=3,0;MQSB=0.880529;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,128:4:0 0,21,186:7:0 +17 677 . T 0 . DP=29;I16=9,20,0,0,1006,36126,0,0,1709,101641,0,0,507,11303,0,0;QS=3,0;MQSB=0.894839;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,120:4:0 0,21,192:7:0 +17 678 . C 0 . DP=29;I16=9,20,0,0,1020,36984,0,0,1709,101641,0,0,502,11280,0,0;QS=3,0;MQSB=0.894839;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,117:4:0 0,21,191:7:0 +17 679 . T 0 . DP=27;I16=6,19,0,0,902,33612,0,0,1469,87241,0,0,460,10414,0,0;QS=3,0;MQSB=0.833024;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,96:3:0 0,21,195:7:0 +17 680 . C 0 . DP=26;I16=7,18,0,0,879,32295,0,0,1469,87241,0,0,468,10482,0,0;QS=3,0;MQSB=0.862128;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,98:3:0 0,21,181:7:0 +17 681 . A 0 . DP=27;I16=7,17,0,0,844,30190,0,0,1409,83641,0,0,465,10425,0,0;QS=3,0;MQSB=0.864405;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,106:3:0 0,21,174:7:0 +17 682 . A 0 . DP=27;I16=7,20,0,0,919,32179,0,0,1589,94441,0,0,500,11096,0,0;QS=3,0;MQSB=0.858077;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,145:5:0 0,21,176:7:0 +17 683 . A 0 . DP=29;I16=8,21,0,0,949,32735,0,0,1709,101641,0,0,499,11103,0,0;QS=3,0;MQSB=0.876998;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,172:6:0 0,21,167:7:0 +17 684 . C 0 . DP=29;I16=6,21,0,0,802,24468,0,0,1589,94441,0,0,473,10459,0,0;QS=3,0;MQSB=0.829029;MQ0F=0 PL:DP:DV 0,45,251:15:0 0,15,118:5:0 0,21,145:7:0 +17 685 . G 0 . DP=28;I16=6,21,0,0,908,32092,0,0,1620,97200,0,0,498,11090,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,130:5:0 0,21,175:7:0 +17 686 . C 0 . DP=28;I16=7,21,0,0,977,35493,0,0,1680,100800,0,0,500,11080,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,170:6:0 0,21,180:7:0 +17 687 . A 0 . DP=28;I16=6,20,0,0,900,31952,0,0,1560,93600,0,0,475,10469,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,175:6:0 0,21,174:7:0 +17 688 . T 0 . DP=27;I16=6,21,0,0,937,33971,0,0,1620,97200,0,0,501,11135,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,153:6:0 0,21,187:7:0 +17 689 . T A, 0 . DP=27;I16=5,20,1,0,829,28967,13,169,1500,90000,60,3600,463,10359,25,625;QS=2.97105,0.0289532,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,28,231,39,234,234:14:1 0,15,116,15,116,116:5:0 0,21,185,21,185,185:7:0 +17 690 . C 0 . DP=27;I16=6,20,0,0,935,34553,0,0,1560,93600,0,0,486,10974,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,146:5:0 0,21,165:7:0 +17 691 . C 0 . DP=26;I16=5,18,0,0,842,31906,0,0,1380,82800,0,0,446,10166,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,129:4:0 0,18,161:6:0 +17 692 . T 0 . DP=26;I16=6,19,0,0,886,32434,0,0,1500,90000,0,0,486,11082,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,146:5:0 0,18,164:6:0 +17 693 . C 0 . DP=27;I16=6,20,0,0,891,31839,0,0,1560,93600,0,0,483,11007,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,141:5:0 0,21,172:7:0 +17 694 . C 0 . DP=27;I16=6,21,0,0,808,25004,0,0,1620,97200,0,0,498,11248,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,242:14:0 0,18,136:6:0 0,21,146:7:0 +17 695 . G 0 . DP=25;I16=4,20,0,0,807,28037,0,0,1440,86400,0,0,476,10692,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,246:13:0 0,18,145:6:0 0,15,124:5:0 +17 696 . T 0 . DP=25;I16=5,20,0,0,896,32870,0,0,1500,90000,0,0,499,11129,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,150:6:0 0,15,141:5:0 +17 697 . G 0 . DP=26;I16=5,19,0,0,852,30594,0,0,1409,83641,0,0,450,9858,0,0;QS=3,0;MQSB=0.796124;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,142:5:0 0,15,120:5:0 +17 698 . T 0 . DP=27;I16=6,20,0,0,917,33201,0,0,1529,90841,0,0,502,11114,0,0;QS=3,0;MQSB=0.83095;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,154:6:0 0,15,131:5:0 +17 699 . G 0 . DP=28;I16=5,21,0,0,923,34103,0,0,1529,90841,0,0,498,10884,0,0;QS=3,0;MQSB=0.79189;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,163:6:0 0,15,132:5:0 +17 700 . A 0 . DP=28;I16=6,22,0,0,989,35833,0,0,1618,95282,0,0,530,11626,0,0;QS=3,0;MQSB=0.904554;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,169:7:0 0,18,148:6:0 +17 701 . A 0 . DP=29;I16=5,23,0,0,992,35956,0,0,1618,95282,0,0,517,11459,0,0;QS=3,0;MQSB=0.864394;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,186:7:0 0,18,144:6:0 +17 702 . A 0 . DP=29;I16=5,23,0,0,1103,44105,0,0,1618,95282,0,0,520,11508,0,0;QS=3,0;MQSB=0.864394;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,204:7:0 0,18,159:6:0 +17 703 . G 0 . DP=29;I16=5,23,0,0,1014,37508,0,0,1618,95282,0,0,522,11534,0,0;QS=3,0;MQSB=0.864394;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,172:7:0 0,18,144:6:0 +17 704 . A T, 0 . DP=29;I16=4,23,1,0,954,34200,16,256,1558,91682,60,3600,499,10963,13,169;QS=2.97064,0.0293578,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.864394;BQB=1;MQ0F=0 PL:DP:DV 0,31,255,45,255,255:16:1 0,18,154,18,154,154:6:0 0,18,139,18,139,139:6:0 +17 705 . A 0 . DP=29;I16=6,22,0,0,1042,39930,0,0,1618,95282,0,0,513,11189,0,0;QS=3,0;MQSB=0.904554;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,189:7:0 0,18,157:6:0 +17 706 . G 0 . DP=30;I16=6,23,0,0,1029,37763,0,0,1678,98882,0,0,513,11225,0,0;QS=3,0;MQSB=0.900586;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,170:7:0 0,18,131:6:0 +17 707 . C 0 . DP=30;I16=5,22,0,0,944,34494,0,0,1558,91682,0,0,464,10040,0,0;QS=3,0;MQSB=0.868709;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,131:5:0 0,18,134:6:0 +17 708 . C 0 . DP=30;I16=6,24,0,0,898,27574,0,0,1738,102482,0,0,540,12010,0,0;QS=3,0;MQSB=0.896846;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,153:8:0 0,18,110:6:0 +17 709 . G 0 . DP=29;I16=5,22,0,0,968,36130,0,0,1558,91682,0,0,507,11343,0,0;QS=3,0;MQSB=0.868709;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,178:8:0 0,15,132:5:0 +17 710 . G 0 . DP=29;I16=5,23,0,0,961,34825,0,0,1618,95282,0,0,533,12029,0,0;QS=3,0;MQSB=0.864394;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,174:8:0 0,15,122:5:0 +17 711 . A 0 . DP=29;I16=6,23,0,0,996,35700,0,0,1647,96123,0,0,565,12723,0,0;QS=3,0;MQSB=0.957107;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,171:7:0 0,18,142:6:0 +17 712 . C 0 . DP=29;I16=6,23,0,0,1069,40863,0,0,1647,96123,0,0,565,12767,0,0;QS=3,0;MQSB=0.957107;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,156:7:0 0,18,146:6:0 +17 713 . T 0 . DP=29;I16=6,23,0,0,1072,40426,0,0,1647,96123,0,0,565,12835,0,0;QS=3,0;MQSB=0.957107;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,187:7:0 0,18,149:6:0 +17 714 . C 0 . DP=28;I16=6,21,0,0,988,37236,0,0,1558,91682,0,0,541,12301,0,0;QS=3,0;MQSB=0.90877;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,153:6:0 0,15,125:5:0 +17 715 . A 0 . DP=28;I16=6,20,0,0,884,31414,0,0,1498,88082,0,0,522,12004,0,0;QS=3,0;MQSB=0.913254;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,138:6:0 0,15,120:5:0 +17 716 . C 0 . DP=29;I16=4,23,0,0,998,37756,0,0,1527,88923,0,0,547,12501,0,0;QS=3,0;MQSB=0.877203;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,141:5:0 0,18,145:6:0 +17 717 . A 0 . DP=31;I16=8,23,0,0,1136,42928,0,0,1767,103323,0,0,574,13254,0,0;QS=3,0;MQSB=0.987595;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,212:8:0 0,18,153:6:0 +17 718 . G 0 . DP=29;I16=7,22,0,0,1066,40006,0,0,1647,96123,0,0,579,13407,0,0;QS=3,0;MQSB=0.979435;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,223:8:0 0,18,139:6:0 +17 719 . G 0 . DP=29;I16=7,19,0,0,952,35868,0,0,1529,90841,0,0,510,11756,0,0;QS=3,0;MQSB=0.860025;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,204:8:0 0,12,120:4:0 +17 720 . G 0 . DP=28;I16=6,20,0,0,986,37838,0,0,1467,85323,0,0,552,12940,0,0;QS=3,0;MQSB=0.970805;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,216:8:0 0,18,147:6:0 +17 721 . C 0 . DP=28;I16=6,21,0,0,989,36901,0,0,1527,88923,0,0,567,13183,0,0;QS=3,0;MQSB=0.966147;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,197:8:0 0,18,147:6:0 +17 722 . A 0 . DP=28;I16=6,21,0,0,949,33837,0,0,1527,88923,0,0,569,13225,0,0;QS=3,0;MQSB=0.966147;MQ0F=0 PL:DP:DV 0,39,244:13:0 0,24,205:8:0 0,18,143:6:0 +17 723 . A 0 . DP=28;I16=6,19,0,0,925,34825,0,0,1438,84482,0,0,530,12366,0,0;QS=3,0;MQSB=0.918029;MQ0F=0 PL:DP:DV 0,36,253:12:0 0,24,206:8:0 0,15,135:5:0 +17 724 . C 0 . DP=28;I16=5,22,0,0,967,35983,0,0,1527,88923,0,0,566,13028,0,0;QS=3,0;MQSB=0.932273;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,161:7:0 0,18,140:6:0 +17 725 . A 0 . DP=28;I16=6,21,0,0,911,31971,0,0,1527,88923,0,0,565,12987,0,0;QS=3,0;MQSB=0.966147;MQ0F=0 PL:DP:DV 0,42,246:14:0 0,21,168:7:0 0,18,137:6:0 +17 726 . C 0 . DP=28;I16=6,21,0,0,947,34531,0,0,1527,88923,0,0,563,12919,0,0;QS=3,0;MQSB=0.966147;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,166:7:0 0,18,136:6:0 +17 727 . A C, 0 . DP=28;I16=6,20,0,1,904,32194,17,289,1498,88082,29,841,535,12199,25,625;QS=2.90811,0.0918919,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.966147;BQB=1;MQ0F=0 PL:DP:DV 0,42,247,42,247,247:14:0 0,21,191,21,191,191:7:0 0,1,109,15,112,119:6:1 +17 728 . C 0 . DP=29;I16=6,22,0,0,1018,37990,0,0,1587,92523,0,0,557,12701,0,0;QS=3,0;MQSB=0.961573;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,208:8:0 0,18,142:6:0 +17 729 . T 0 . DP=29;I16=7,22,0,0,1063,39315,0,0,1647,96123,0,0,581,13227,0,0;QS=3,0;MQSB=0.979435;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,244:9:0 0,18,142:6:0 +17 730 . A 0 . DP=29;I16=7,21,0,0,993,35883,0,0,1618,95282,0,0,555,12529,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,219:9:0 0,15,135:5:0 +17 731 . T 0 . DP=29;I16=7,22,0,0,1024,37312,0,0,1647,96123,0,0,578,13058,0,0;QS=3,0;MQSB=0.979435;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,210:9:0 0,18,148:6:0 +17 732 . C 0 . DP=29;I16=7,21,0,0,1006,37058,0,0,1618,95282,0,0,550,12314,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,219:9:0 0,15,129:5:0 +17 733 . T 0 . DP=29;I16=7,21,0,0,985,35497,0,0,1618,95282,0,0,547,12221,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,222:9:0 0,15,134:5:0 +17 734 . G 0 . DP=29;I16=7,21,0,0,997,36453,0,0,1587,92523,0,0,544,12154,0,0;QS=3,0;MQSB=0.982906;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,204:8:0 0,18,139:6:0 +17 735 . A 0 . DP=30;I16=7,21,0,0,963,33993,0,0,1618,95282,0,0,515,11437,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,190:8:0 0,18,148:6:0 +17 736 . C 0 . DP=30;I16=8,20,0,0,1042,39326,0,0,1618,95282,0,0,512,11320,0,0;QS=3,0;MQSB=0.954515;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,218:8:0 0,18,152:6:0 +17 737 . T 0 . DP=30;I16=8,22,0,0,1071,39825,0,0,1707,99723,0,0,560,12480,0,0;QS=3,0;MQSB=0.990151;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,243:9:0 0,21,149:7:0 +17 738 . G 0 . DP=30;I16=8,21,0,0,1016,36816,0,0,1678,98882,0,0,533,11793,0,0;QS=3,0;MQSB=0.950946;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,210:9:0 0,18,141:6:0 +17 739 . T 0 . DP=30;I16=7,22,0,0,1020,37326,0,0,1647,96123,0,0,534,11900,0,0;QS=3,0;MQSB=0.979435;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,202:8:0 0,21,155:7:0 +17 740 . T 0 . DP=29;I16=7,21,0,0,1011,37465,0,0,1587,92523,0,0,532,11848,0,0;QS=3,0;MQSB=0.982906;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,232:8:0 0,21,155:7:0 +17 741 . T 0 . DP=29;I16=7,21,0,0,984,36052,0,0,1587,92523,0,0,528,11722,0,0;QS=3,0;MQSB=0.982906;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,224:8:0 0,21,151:7:0 +17 742 . C 0 . DP=30;I16=8,21,0,0,1046,39056,0,0,1678,98882,0,0,525,11671,0,0;QS=3,0;MQSB=0.950946;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,243:9:0 0,18,136:6:0 +17 743 . A 0 . DP=30;I16=8,21,0,0,1026,37156,0,0,1678,98882,0,0,520,11500,0,0;QS=3,0;MQSB=0.950946;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,239:9:0 0,18,131:6:0 +17 744 . T 0 . DP=30;I16=8,22,0,0,1100,41010,0,0,1707,99723,0,0,540,11984,0,0;QS=3,0;MQSB=0.990151;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,247:9:0 0,21,154:7:0 +17 745 . G 0 . DP=31;I16=9,22,0,0,1078,38890,0,0,1767,103323,0,0,535,11873,0,0;QS=3,0;MQSB=0.996219;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,227:9:0 0,24,178:8:0 +17 746 . G 0 . DP=31;I16=9,21,0,0,1001,35191,0,0,1707,99723,0,0,531,11793,0,0;QS=3,0;MQSB=0.997698;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,201:9:0 0,24,178:8:0 +17 747 . G 0 . DP=30;I16=9,20,0,0,1017,36831,0,0,1647,96123,0,0,509,11343,0,0;QS=3,0;MQSB=0.99889;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,201:8:0 0,21,174:7:0 +17 748 . A 0 . DP=30;I16=10,20,0,0,1046,37438,0,0,1707,99723,0,0,529,11721,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,242:9:0 0,18,159:6:0 +17 749 . A 0 . DP=31;I16=10,21,0,0,1077,38303,0,0,1767,103323,0,0,530,11728,0,0;QS=3,0;MQSB=0.999777;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,27,240:9:0 0,18,164:6:0 +17 750 . A 0 . DP=32;I16=10,20,0,0,1129,43093,0,0,1738,102482,0,0,500,11252,0,0;QS=3,0;MQSB=0.976097;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,232:8:0 0,15,161:5:0 +17 751 . G 0 . DP=31;I16=11,20,0,0,1065,37955,0,0,1767,103323,0,0,535,11787,0,0;QS=3,0;MQSB=0.999148;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,27,206:9:0 0,18,150:6:0 +17 752 . T 0 . DP=31;I16=11,20,0,0,1034,35786,0,0,1767,103323,0,0,537,11793,0,0;QS=3,0;MQSB=0.999148;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,27,223:9:0 0,18,143:6:0 +17 753 . C 0 . DP=31;I16=12,19,0,0,1073,38779,0,0,1767,103323,0,0,540,11834,0,0;QS=3,0;MQSB=0.994873;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,30,227:10:0 0,18,158:6:0 +17 754 . T 0 . DP=31;I16=12,19,0,0,1135,42527,0,0,1767,103323,0,0,542,11808,0,0;QS=3,0;MQSB=0.994873;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,30,255:10:0 0,18,172:6:0 +17 755 . G 0 . DP=31;I16=12,19,0,0,1157,43695,0,0,1767,103323,0,0,544,11814,0,0;QS=3,0;MQSB=0.994873;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,30,255:10:0 0,18,162:6:0 +17 756 . G 0 . DP=30;I16=12,17,0,0,1002,35566,0,0,1647,96123,0,0,539,11753,0,0;QS=3,0;MQSB=0.988062;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,30,242:10:0 0,18,157:6:0 +17 757 . A 0 . DP=30;I16=12,17,0,0,1035,37723,0,0,1678,98882,0,0,523,11197,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,30,248:10:0 0,15,152:5:0 +17 758 . A 0 . DP=30;I16=12,18,0,0,1015,35685,0,0,1707,99723,0,0,549,11825,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,30,247:10:0 0,18,156:6:0 +17 759 . A 0 . DP=30;I16=12,16,0,0,998,36498,0,0,1618,95282,0,0,526,11472,0,0;QS=3,0;MQSB=0.995699;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,242:9:0 0,15,151:5:0 +17 760 . C 0 . DP=31;I16=12,18,0,0,916,29466,0,0,1707,99723,0,0,547,11741,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,30,217:10:0 0,18,128:6:0 +17 761 . G 0 . DP=30;I16=11,16,0,0,932,32884,0,0,1589,94441,0,0,512,11028,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,220:9:0 0,15,153:5:0 +17 762 . G 0 . DP=29;I16=11,18,0,0,1012,36984,0,0,1647,96123,0,0,541,11629,0,0;QS=3,0;MQSB=0.995968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,220:9:0 0,21,173:7:0 +17 763 . C A, 0 . DP=29;I16=11,16,0,1,948,35124,15,225,1558,91682,29,841,527,11473,2,4;QS=2.93697,0.0630252,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.993109;BQB=1;MQ0F=0 PL:DP:DV 0,39,255,39,255,255:13:0 0,24,193,24,193,193:8:0 0,6,158,18,161,165:7:1 +17 764 . A 0 . DP=31;I16=12,18,0,0,1051,37737,0,0,1738,102482,0,0,516,11020,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,30,250:10:0 0,18,163:6:0 +17 765 . A 0 . DP=32;I16=12,18,0,0,1071,39369,0,0,1738,102482,0,0,525,11379,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,30,254:10:0 0,18,169:6:0 +17 766 . C 0 . DP=31;I16=13,18,0,0,1065,38285,0,0,1798,106082,0,0,547,11797,0,0;QS=3,0;MQSB=0.995005;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,33,235:11:0 0,18,164:6:0 +17 767 . A 0 . DP=30;I16=12,18,0,0,996,34692,0,0,1738,102482,0,0,552,11926,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,244:11:0 0,18,148:6:0 +17 768 . C 0 . DP=30;I16=12,18,0,0,1095,40739,0,0,1738,102482,0,0,556,12038,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,255:11:0 0,18,173:6:0 +17 769 . C 0 . DP=30;I16=12,18,0,0,1110,42272,0,0,1738,102482,0,0,559,12133,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,255:11:0 0,18,173:6:0 +17 770 . A 0 . DP=30;I16=12,18,0,0,1098,40852,0,0,1738,102482,0,0,562,12262,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,255:11:0 0,18,171:6:0 +17 771 . T 0 . DP=30;I16=12,18,0,0,1111,41771,0,0,1738,102482,0,0,563,12325,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,255:11:0 0,18,177:6:0 +17 772 . T 0 . DP=30;I16=12,18,0,0,1107,41429,0,0,1738,102482,0,0,563,12373,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,255:11:0 0,18,176:6:0 +17 773 . G 0 . DP=30;I16=12,18,0,0,1123,42761,0,0,1738,102482,0,0,562,12406,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,255:11:0 0,18,175:6:0 +17 774 . A 0 . DP=30;I16=12,18,0,0,1151,44801,0,0,1738,102482,0,0,560,12422,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,255:11:0 0,18,179:6:0 +17 775 . G 0 . DP=30;I16=12,18,0,0,1136,43766,0,0,1738,102482,0,0,557,12419,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,33,255:11:0 0,18,177:6:0 +17 776 . A 0 . DP=29;I16=12,17,0,0,1053,38865,0,0,1678,98882,0,0,553,12345,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,30,255:10:0 0,18,169:6:0 +17 777 . C 0 . DP=28;I16=12,16,0,0,1019,37631,0,0,1618,95282,0,0,550,12298,0,0;QS=3,0;MQSB=0.995699;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,229:9:0 0,18,165:6:0 +17 778 . A 0 . DP=28;I16=12,16,0,0,1079,42041,0,0,1618,95282,0,0,547,12277,0,0;QS=3,0;MQSB=0.995699;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,241:9:0 0,18,181:6:0 +17 779 . G 0 . DP=28;I16=12,16,0,0,1025,38825,0,0,1618,95282,0,0,543,12231,0,0;QS=3,0;MQSB=0.995699;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,231:9:0 0,18,170:6:0 +17 780 . A 0 . DP=28;I16=12,16,0,0,1005,36773,0,0,1618,95282,0,0,538,12160,0,0;QS=3,0;MQSB=0.995699;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,242:9:0 0,18,166:6:0 +17 781 . A 0 . DP=28;I16=12,15,0,0,965,35857,0,0,1589,94441,0,0,519,11889,0,0;QS=3,0;MQSB=0.935229;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,222:8:0 0,15,159:5:0 +17 782 . A 0 . DP=28;I16=12,16,0,0,1003,37315,0,0,1618,95282,0,0,530,12044,0,0;QS=3,0;MQSB=0.995699;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,229:8:0 0,18,171:6:0 +17 783 . A 0 . DP=28;I16=12,16,0,0,989,36477,0,0,1618,95282,0,0,527,12001,0,0;QS=3,0;MQSB=0.995699;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,230:8:0 0,21,178:7:0 +17 784 . C 0 . DP=26;I16=11,15,0,0,967,36387,0,0,1498,88082,0,0,527,11983,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,207:7:0 0,21,178:7:0 +17 785 . A 0 . DP=26;I16=11,15,0,0,989,38499,0,0,1498,88082,0,0,527,11989,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,213:7:0 0,21,187:7:0 +17 786 . G 0 . DP=26;I16=11,14,0,0,938,35698,0,0,1438,84482,0,0,501,11343,0,0;QS=3,0;MQSB=0.996634;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,211:7:0 0,21,180:7:0 +17 787 . G 0 . DP=26;I16=11,15,0,0,914,33428,0,0,1498,88082,0,0,525,11969,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,189:7:0 0,21,175:7:0 +17 788 . T 0 . DP=26;I16=11,15,0,0,913,33357,0,0,1498,88082,0,0,524,11992,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,180:7:0 0,21,188:7:0 +17 789 . G 0 . DP=26;I16=11,15,0,0,963,36645,0,0,1498,88082,0,0,523,12037,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,193:7:0 0,21,183:7:0 +17 790 . A 0 . DP=26;I16=11,15,0,0,999,39113,0,0,1498,88082,0,0,520,12002,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,198:7:0 0,21,201:7:0 +17 791 . G 0 . DP=26;I16=11,15,0,0,934,34208,0,0,1498,88082,0,0,516,11934,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,180:7:0 0,21,172:7:0 +17 792 . T 0 . DP=26;I16=11,15,0,0,895,32009,0,0,1498,88082,0,0,511,11833,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,184:7:0 0,21,172:7:0 +17 793 . G 0 . DP=27;I16=11,15,0,0,965,36389,0,0,1498,88082,0,0,504,11652,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,193:7:0 0,21,170:7:0 +17 794 . G 0 . DP=26;I16=11,15,0,0,888,31804,0,0,1498,88082,0,0,508,11592,0,0;QS=3,0;MQSB=0.994627;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,198:8:0 0,18,161:6:0 +17 795 . T 0 . DP=26;I16=9,15,0,0,859,31399,0,0,1409,83641,0,0,472,10908,0,0;QS=3,0;MQSB=0.96464;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,211:7:0 0,18,160:6:0 +17 796 . T 0 . DP=27;I16=11,16,0,0,907,31641,0,0,1558,91682,0,0,499,11375,0,0;QS=3,0;MQSB=0.992419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,221:9:0 0,15,150:5:0 +17 797 . G 0 . DP=26;I16=11,15,0,0,882,31700,0,0,1529,90841,0,0,498,11298,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,215:9:0 0,12,135:4:0 +17 798 . C 0 . DP=26;I16=9,15,0,0,806,28552,0,0,1440,86400,0,0,466,10582,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,207:8:0 0,12,126:4:0 +17 799 . C 0 . DP=26;I16=10,15,0,0,947,36407,0,0,1500,90000,0,0,491,11185,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,234:9:0 0,12,137:4:0 +17 800 . T 0 . DP=26;I16=11,15,0,0,993,38475,0,0,1529,90841,0,0,495,11199,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,27,255:9:0 0,12,139:4:0 +17 801 . G 0 . DP=25;I16=11,14,0,0,938,35854,0,0,1469,87241,0,0,495,11209,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,240:9:0 0,12,145:4:0 +17 802 . G 0 . DP=25;I16=11,14,0,0,892,32802,0,0,1469,87241,0,0,495,11239,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,229:9:0 0,12,137:4:0 +17 803 . G 0 . DP=25;I16=11,14,0,0,906,33502,0,0,1469,87241,0,0,495,11289,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,237:9:0 0,12,136:4:0 +17 804 . G 0 . DP=25;I16=11,12,0,0,868,33326,0,0,1349,80041,0,0,466,10846,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,223:8:0 0,12,138:4:0 +17 805 . C 0 . DP=24;I16=9,14,0,0,810,29684,0,0,1380,82800,0,0,482,11208,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,220:8:0 0,12,128:4:0 +17 806 . C 0 . DP=25;I16=9,14,0,0,814,29856,0,0,1380,82800,0,0,483,11293,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,214:8:0 0,12,122:4:0 +17 807 . A 0 . DP=25;I16=10,15,0,0,939,35997,0,0,1500,90000,0,0,503,11525,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,242:9:0 0,12,146:4:0 +17 808 . G 0 . DP=25;I16=10,15,0,0,918,34720,0,0,1500,90000,0,0,505,11591,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,238:9:0 0,12,136:4:0 +17 809 . G 0 . DP=25;I16=10,15,0,0,926,34932,0,0,1500,90000,0,0,506,11626,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,226:9:0 0,12,136:4:0 +17 810 . G C, 0 . DP=25;I16=10,13,0,1,824,30436,14,196,1380,82800,60,3600,480,11288,14,196;QS=2.96552,0.0344828,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,21,255,33,255,255:12:1 0,24,216,24,216,216:8:0 0,12,132,12,132,132:4:0 +17 811 . A 0 . DP=25;I16=9,14,0,0,808,29404,0,0,1380,82800,0,0,484,11294,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,204:7:0 0,12,139:4:0 +17 812 . A 0 . DP=25;I16=10,15,0,0,831,29515,0,0,1500,90000,0,0,500,11392,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,216:9:0 0,12,139:4:0 +17 813 . C 0 . DP=25;I16=10,15,0,0,915,34093,0,0,1500,90000,0,0,497,11307,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,239:9:0 0,12,138:4:0 +17 814 . T 0 . DP=25;I16=10,15,0,0,987,39343,0,0,1500,90000,0,0,494,11244,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,255:9:0 0,12,148:4:0 +17 815 . T 0 . DP=25;I16=10,15,0,0,894,32670,0,0,1500,90000,0,0,491,11203,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,235:9:0 0,12,143:4:0 +17 816 . T 0 . DP=25;I16=10,15,0,0,898,32990,0,0,1500,90000,0,0,488,11184,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,239:9:0 0,12,136:4:0 +17 817 . C 0 . DP=24;I16=10,14,0,0,898,34256,0,0,1440,86400,0,0,485,11137,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,235:9:0 0,12,124:4:0 +17 818 . T 0 . DP=23;I16=9,14,0,0,883,34371,0,0,1380,82800,0,0,484,11110,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,225:8:0 0,12,143:4:0 +17 819 . G 0 . DP=23;I16=9,13,0,0,832,31932,0,0,1320,79200,0,0,461,10573,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,217:8:0 0,12,142:4:0 +17 820 . G 0 . DP=24;I16=10,14,0,0,844,30848,0,0,1440,86400,0,0,484,11114,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,230:9:0 0,12,135:4:0 +17 821 . G 0 . DP=24;I16=10,14,0,0,852,31572,0,0,1440,86400,0,0,484,11098,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,234:9:0 0,12,142:4:0 +17 822 . G 0 . DP=25;I16=10,15,0,0,879,31785,0,0,1500,90000,0,0,481,10955,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,220:9:0 0,12,127:4:0 +17 823 . T 0 . DP=25;I16=10,15,0,0,844,29686,0,0,1500,90000,0,0,478,10786,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,217:9:0 0,12,127:4:0 +17 824 . C 0 . DP=25;I16=9,14,0,0,824,30252,0,0,1380,82800,0,0,427,9477,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,215:9:0 0,9,98:3:0 +17 825 . A 0 . DP=25;I16=10,15,0,0,881,31665,0,0,1500,90000,0,0,467,10277,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,234:9:0 0,12,116:4:0 +17 826 . T 0 . DP=25;I16=10,15,0,0,826,28364,0,0,1500,90000,0,0,461,10039,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,250:12:0 0,27,232:9:0 0,12,117:4:0 +17 827 . A 0 . DP=25;I16=10,15,0,0,851,29477,0,0,1500,90000,0,0,455,9829,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,227:9:0 0,12,123:4:0 +17 828 . T C, 0 . DP=25;I16=2,4,8,11,199,6917,656,23340,360,21600,1140,68400,116,2716,333,6931;QS=0.597777,2.40222,0;VDB=0.842082;SGB=-4.20907;RPB=0.950652;MQB=1;MQSB=1;BQB=0.929717;MQ0F=0 PL:DP:DV 211,0,35,217,65,255:12:10 116,0,91,128,106,213:9:5 120,12,0,120,12,120:4:4 +17 829 . T 0 . DP=24;I16=10,13,0,0,863,32931,0,0,1380,82800,0,0,418,8818,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,242:8:0 0,12,132:4:0 +17 830 . C 0 . DP=24;I16=10,14,0,0,910,34966,0,0,1440,86400,0,0,437,9267,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,220:8:0 0,12,134:4:0 +17 831 . T 0 . DP=24;I16=10,14,0,0,906,34886,0,0,1440,86400,0,0,431,9119,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,243:8:0 0,12,133:4:0 +17 832 . C 0 . DP=24;I16=10,14,0,0,888,33634,0,0,1440,86400,0,0,425,8999,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,220:8:0 0,12,123:4:0 +17 833 . T 0 . DP=25;I16=10,14,0,0,820,29920,0,0,1440,86400,0,0,418,8856,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,224:8:0 0,12,113:4:0 +17 834 . G A, 0 . DP=25;I16=2,3,7,10,164,5898,590,21124,300,18000,1020,61200,104,2296,305,6441;QS=0.520056,2.47994,0;VDB=0.788006;SGB=-4.01214;RPB=0.999233;MQB=1;MQSB=1;BQB=0.821668;MQ0F=0 PL:DP:DV 185,0,46,191,73,246:11:9 128,0,59,137,74,193:8:5 89,9,0,89,9,89:3:3 +17 835 . T 0 . DP=26;I16=9,15,0,0,767,26675,0,0,1440,86400,0,0,406,8652,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,240:12:0 0,24,213:8:0 0,12,98:4:0 +17 836 . G 0 . DP=23;I16=8,15,0,0,833,30561,0,0,1380,82800,0,0,403,8541,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,243:11:0 0,24,214:8:0 0,12,130:4:0 +17 837 . T 0 . DP=23;I16=8,15,0,0,843,31499,0,0,1380,82800,0,0,400,8456,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,241:11:0 0,24,221:8:0 0,12,143:4:0 +17 838 . T 0 . DP=23;I16=8,15,0,0,870,33172,0,0,1380,82800,0,0,397,8397,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,252:11:0 0,24,224:8:0 0,12,134:4:0 +17 839 . G 0 . DP=24;I16=8,15,0,0,862,32774,0,0,1380,82800,0,0,393,8315,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,249:11:0 0,24,212:8:0 0,12,142:4:0 +17 840 . A 0 . DP=25;I16=9,15,0,0,876,32682,0,0,1440,86400,0,0,375,7731,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,243:11:0 0,21,196:7:0 0,18,180:6:0 +17 841 . T 0 . DP=25;I16=9,16,0,0,861,30879,0,0,1500,90000,0,0,396,8260,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,213:11:0 0,24,226:8:0 0,18,185:6:0 +17 842 . T 0 . DP=24;I16=9,15,0,0,872,31990,0,0,1440,86400,0,0,393,8199,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,227:10:0 0,24,231:8:0 0,18,175:6:0 +17 843 . C 0 . DP=24;I16=9,15,0,0,844,30604,0,0,1440,86400,0,0,390,8172,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,228:10:0 0,24,229:8:0 0,18,160:6:0 +17 844 . T 0 . DP=24;I16=9,15,0,0,900,34094,0,0,1440,86400,0,0,386,8128,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,227:10:0 0,24,238:8:0 0,18,189:6:0 +17 845 . G 0 . DP=25;I16=10,15,0,0,916,33866,0,0,1500,90000,0,0,382,8116,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,239:10:0 0,24,225:8:0 0,21,196:7:0 +17 846 . G 0 . DP=24;I16=9,14,0,0,802,28414,0,0,1380,82800,0,0,354,7460,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,223:9:0 0,24,208:8:0 0,18,164:6:0 +17 847 . T 0 . DP=24;I16=8,15,0,0,809,29007,0,0,1380,82800,0,0,377,8083,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,210:9:0 0,24,219:8:0 0,18,149:6:0 +17 848 . G 0 . DP=23;I16=8,15,0,0,829,30351,0,0,1380,82800,0,0,384,8138,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,199:8:0 0,27,243:9:0 0,18,167:6:0 +17 849 . G 0 . DP=22;I16=8,12,0,0,684,23844,0,0,1200,72000,0,0,349,7517,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,160:6:0 0,27,233:9:0 0,15,140:5:0 +17 850 . T 0 . DP=21;I16=6,14,0,0,706,25508,0,0,1200,72000,0,0,360,7568,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,153:6:0 0,24,226:8:0 0,18,147:6:0 +17 851 . G 0 . DP=21;I16=7,14,0,0,707,24667,0,0,1260,75600,0,0,386,8254,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,140:6:0 0,27,233:9:0 0,18,156:6:0 +17 852 . G 0 . DP=21;I16=7,13,0,0,687,24223,0,0,1200,72000,0,0,368,7976,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,147:6:0 0,27,222:9:0 0,15,146:5:0 +17 853 . A 0 . DP=21;I16=7,14,0,0,721,25603,0,0,1260,75600,0,0,388,8442,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,146:6:0 0,27,223:9:0 0,18,166:6:0 +17 854 . A 0 . DP=21;I16=7,14,0,0,725,25843,0,0,1260,75600,0,0,389,8517,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,179:7:0 0,24,209:8:0 0,18,168:6:0 +17 855 . A 0 . DP=21;I16=7,14,0,0,683,23803,0,0,1260,75600,0,0,391,8611,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,171:7:0 0,24,204:8:0 0,18,152:6:0 +17 856 . C 0 . DP=21;I16=7,14,0,0,763,28293,0,0,1260,75600,0,0,392,8676,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,192:7:0 0,24,222:8:0 0,18,172:6:0 +17 857 . A 0 . DP=22;I16=8,14,0,0,786,28480,0,0,1320,79200,0,0,393,8763,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,182:7:0 0,24,220:8:0 0,21,194:7:0 +17 858 . A 0 . DP=22;I16=8,14,0,0,816,31358,0,0,1320,79200,0,0,395,8873,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,192:7:0 0,24,236:8:0 0,21,198:7:0 +17 859 . G 0 . DP=22;I16=8,14,0,0,824,31356,0,0,1320,79200,0,0,395,8907,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,202:7:0 0,24,223:8:0 0,21,203:7:0 +17 860 . A 0 . DP=22;I16=8,13,0,0,743,26985,0,0,1260,75600,0,0,369,8291,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,184:7:0 0,21,202:7:0 0,21,190:7:0 +17 861 . C 0 . DP=22;I16=8,14,0,0,770,28376,0,0,1320,79200,0,0,393,8899,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,206:8:0 0,24,216:8:0 0,18,161:6:0 +17 862 . T 0 . DP=22;I16=8,14,0,0,762,27500,0,0,1320,79200,0,0,393,8905,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,188:8:0 0,24,213:8:0 0,18,177:6:0 +17 863 . G 0 . DP=23;I16=9,14,0,0,836,30660,0,0,1380,82800,0,0,393,8935,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,24,221:8:0 0,18,180:6:0 +17 864 . T 0 . DP=22;I16=9,13,0,0,795,29085,0,0,1320,79200,0,0,395,8989,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,215:8:0 0,24,221:8:0 0,18,180:6:0 +17 865 . C 0 . DP=22;I16=8,14,0,0,785,28475,0,0,1320,79200,0,0,397,9015,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,21,193:7:0 0,18,177:6:0 +17 866 . C 0 . DP=21;I16=7,13,0,0,694,24890,0,0,1200,72000,0,0,395,8985,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,220:8:0 0,18,149:6:0 0,18,177:6:0 +17 867 . C 0 . DP=21;I16=7,14,0,0,761,28443,0,0,1260,75600,0,0,403,9023,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,223:9:0 0,18,182:6:0 0,18,187:6:0 +17 868 . A 0 . DP=21;I16=7,14,0,0,799,31183,0,0,1260,75600,0,0,406,9054,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,18,189:6:0 0,18,202:6:0 +17 869 . G 0 . DP=21;I16=7,14,0,0,795,30733,0,0,1260,75600,0,0,409,9103,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,236:9:0 0,18,190:6:0 0,18,187:6:0 +17 870 . C 0 . DP=21;I16=7,13,0,0,758,29080,0,0,1200,72000,0,0,403,9089,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,226:8:0 0,18,183:6:0 0,18,187:6:0 +17 871 . C 0 . DP=21;I16=7,14,0,0,769,29383,0,0,1260,75600,0,0,413,9155,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,232:9:0 0,18,176:6:0 0,18,192:6:0 +17 872 . T 0 . DP=21;I16=7,14,0,0,785,29879,0,0,1260,75600,0,0,413,9109,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,18,187:6:0 0,18,188:6:0 +17 873 . G 0 . DP=21;I16=7,14,0,0,768,28506,0,0,1260,75600,0,0,413,9083,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,18,172:6:0 0,18,182:6:0 +17 874 . G 0 . DP=21;I16=7,12,0,0,700,26434,0,0,1140,68400,0,0,374,8234,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,227:8:0 0,15,143:5:0 0,18,189:6:0 +17 875 . G 0 . DP=21;I16=7,14,0,0,717,25659,0,0,1260,75600,0,0,411,8995,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,18,163:6:0 0,18,159:6:0 +17 876 . T 0 . DP=21;I16=7,14,0,0,719,25261,0,0,1260,75600,0,0,410,8984,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,222:9:0 0,18,156:6:0 0,18,173:6:0 +17 877 . G 0 . DP=21;I16=7,14,0,0,747,27419,0,0,1260,75600,0,0,409,8995,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,235:9:0 0,18,162:6:0 0,18,176:6:0 +17 878 . A 0 . DP=21;I16=7,13,0,0,738,27650,0,0,1200,72000,0,0,391,8739,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,216:8:0 0,18,172:6:0 0,18,191:6:0 +17 879 . T 0 . DP=21;I16=7,13,0,0,731,26927,0,0,1200,72000,0,0,389,8759,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,214:8:0 0,18,175:6:0 0,18,184:6:0 +17 880 . A 0 . DP=21;I16=7,14,0,0,737,26481,0,0,1260,75600,0,0,405,9109,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,18,165:6:0 0,18,172:6:0 +17 881 . C 0 . DP=20;I16=7,13,0,0,742,27898,0,0,1200,72000,0,0,404,9154,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,231:8:0 0,18,164:6:0 0,18,183:6:0 +17 882 . A 0 . DP=20;I16=7,13,0,0,776,30564,0,0,1200,72000,0,0,403,9217,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,225:8:0 0,18,188:6:0 0,18,200:6:0 +17 883 . G 0 . DP=20;I16=7,13,0,0,702,25898,0,0,1200,72000,0,0,401,9247,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,214:8:0 0,18,175:6:0 0,18,176:6:0 +17 884 . C 0 . DP=19;I16=7,12,0,0,629,21449,0,0,1140,68400,0,0,400,9292,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,201:8:0 0,18,155:6:0 0,15,144:5:0 +17 885 . G 0 . DP=18;I16=7,11,0,0,605,20851,0,0,1080,64800,0,0,400,9350,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,215:8:0 0,15,140:5:0 0,15,130:5:0 +17 886 . A 0 . DP=18;I16=7,11,0,0,681,26145,0,0,1080,64800,0,0,400,9420,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,222:8:0 0,15,164:5:0 0,15,163:5:0 +17 887 . G 0 . DP=18;I16=7,11,0,0,631,22891,0,0,1080,64800,0,0,399,9451,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,222:8:0 0,15,138:5:0 0,15,149:5:0 +17 888 . A 0 . DP=18;I16=7,10,0,0,593,21563,0,0,1020,61200,0,0,373,8867,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,216:8:0 0,15,132:5:0 0,12,127:4:0 +17 889 . C 0 . DP=18;I16=7,11,0,0,624,22732,0,0,1080,64800,0,0,396,9492,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,213:8:0 0,15,134:5:0 0,15,160:5:0 +17 890 . C 0 . DP=19;I16=7,11,0,0,616,22426,0,0,1080,64800,0,0,368,8826,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,215:8:0 0,15,138:5:0 0,15,152:5:0 +17 891 . C 0 . DP=19;I16=7,11,0,0,661,24891,0,0,1080,64800,0,0,365,8745,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,227:8:0 0,15,141:5:0 0,15,165:5:0 +17 892 . C 0 . DP=19;I16=7,12,0,0,691,25761,0,0,1140,68400,0,0,387,9299,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,230:9:0 0,15,146:5:0 0,15,167:5:0 +17 893 . A 0 . DP=19;I16=7,12,0,0,673,24521,0,0,1140,68400,0,0,384,9238,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,221:9:0 0,15,142:5:0 0,15,166:5:0 +17 894 . T 0 . DP=19;I16=7,12,0,0,670,24268,0,0,1140,68400,0,0,380,9138,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,225:9:0 0,15,134:5:0 0,15,165:5:0 +17 895 . C 0 . DP=20;I16=8,12,0,0,712,26186,0,0,1200,72000,0,0,376,9050,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,15,149:5:0 0,15,162:5:0 +17 896 . T 0 . DP=19;I16=8,10,0,0,684,26696,0,0,1080,64800,0,0,348,8300,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,12,141:4:0 0,15,180:5:0 +17 897 . C 0 . DP=18;I16=8,10,0,0,693,27001,0,0,1080,64800,0,0,370,8764,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,12,131:4:0 0,15,166:5:0 +17 898 . T 0 . DP=18;I16=8,10,0,0,674,25656,0,0,1080,64800,0,0,367,8617,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,243:9:0 0,12,125:4:0 0,15,172:5:0 +17 899 . A 0 . DP=18;I16=9,8,0,0,597,21451,0,0,1020,61200,0,0,340,7858,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,9,99:3:0 0,15,145:5:0 +17 900 . C 0 . DP=18;I16=9,9,0,0,658,24550,0,0,1080,64800,0,0,364,8362,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,98:3:0 0,15,166:5:0 +17 901 . C 0 . DP=18;I16=9,9,0,0,680,26004,0,0,1080,64800,0,0,363,8255,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,99:3:0 0,15,169:5:0 +17 902 . A 0 . DP=18;I16=9,9,0,0,681,26253,0,0,1080,64800,0,0,362,8162,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,9,115:3:0 0,15,174:5:0 +17 903 . A 0 . DP=18;I16=9,8,0,0,645,24625,0,0,1020,61200,0,0,336,7458,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,250:9:0 0,9,101:3:0 0,15,171:5:0 +17 904 . A 0 . DP=18;I16=9,9,0,0,640,23412,0,0,1080,64800,0,0,359,7969,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,9,85:3:0 0,15,174:5:0 +17 905 . A 0 . DP=18;I16=9,9,0,0,675,25673,0,0,1080,64800,0,0,357,7871,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,103:3:0 0,15,172:5:0 +17 906 . A 0 . DP=18;I16=9,9,0,0,669,25193,0,0,1080,64800,0,0,355,7789,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,102:3:0 0,15,166:5:0 +17 907 . A 0 . DP=18;I16=9,9,0,0,661,24541,0,0,1080,64800,0,0,353,7723,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,94:3:0 0,15,165:5:0 +17 908 . T 0 . DP=18;I16=9,9,0,0,673,25579,0,0,1080,64800,0,0,351,7673,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,83:3:0 0,15,168:5:0 +17 909 . T 0 . DP=18;I16=9,9,0,0,653,23847,0,0,1080,64800,0,0,348,7590,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,95:3:0 0,15,161:5:0 +17 910 . A 0 . DP=18;I16=9,9,0,0,652,23790,0,0,1080,64800,0,0,344,7476,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,9,104:3:0 0,15,162:5:0 +17 911 . A 0 . DP=18;I16=9,9,0,0,688,26440,0,0,1080,64800,0,0,340,7382,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,109:3:0 0,15,168:5:0 +17 912 . A 0 . DP=18;I16=9,9,0,0,691,26705,0,0,1080,64800,0,0,336,7308,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,115:3:0 0,15,173:5:0 +17 913 . A 0 . DP=19;I16=9,10,0,0,692,25762,0,0,1140,68400,0,0,332,7254,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,109:3:0 0,15,171:5:0 +17 914 . A 0 . DP=19;I16=9,10,0,0,712,26966,0,0,1140,68400,0,0,329,7221,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,109:3:0 0,15,164:5:0 +17 915 . T 0 . DP=18;I16=9,9,0,0,638,23228,0,0,1080,64800,0,0,326,7160,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,9,99:3:0 0,15,163:5:0 +17 916 . T 0 . DP=19;I16=9,8,0,0,626,23136,0,0,1020,61200,0,0,296,6396,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,9,103:3:0 0,15,164:5:0 +17 917 . A 0 . DP=19;I16=9,10,0,0,726,27962,0,0,1117,66169,0,0,318,6908,0,0;QS=3,0;MQSB=0.934728;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,125:4:0 0,15,171:5:0 +17 918 . G 0 . DP=19;I16=9,10,0,0,688,25456,0,0,1117,66169,0,0,314,6818,0,0;QS=3,0;MQSB=0.934728;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,129:4:0 0,15,147:5:0 +17 919 . C 0 . DP=18;I16=8,10,0,0,672,25786,0,0,1057,62569,0,0,311,6751,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,92:3:0 0,15,152:5:0 +17 920 . T 0 . DP=18;I16=8,10,0,0,681,26113,0,0,1057,62569,0,0,308,6706,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,95:3:0 0,15,171:5:0 +17 921 . G 0 . DP=17;I16=7,10,0,0,617,22841,0,0,997,58969,0,0,304,6582,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,6,47:2:0 0,15,164:5:0 +17 922 . G 0 . DP=16;I16=7,8,0,0,560,21156,0,0,877,51769,0,0,276,5852,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,24,243:8:0 0,6,64:2:0 0,15,151:5:0 +17 923 . G 0 . DP=16;I16=7,8,0,0,562,21350,0,0,877,51769,0,0,273,5765,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,24,245:8:0 0,6,65:2:0 0,15,144:5:0 +17 924 . C 0 . DP=16;I16=7,9,0,0,603,22955,0,0,937,55369,0,0,295,6321,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,6,57:2:0 0,15,157:5:0 +17 925 . A 0 . DP=16;I16=7,9,0,0,576,21618,0,0,937,55369,0,0,291,6219,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,6,58:2:0 0,15,163:5:0 +17 926 . T 0 . DP=16;I16=7,9,0,0,585,22015,0,0,937,55369,0,0,287,6133,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,6,63:2:0 0,15,161:5:0 +17 927 . G 0 . DP=17;I16=7,10,0,0,641,24481,0,0,997,58969,0,0,283,6063,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,9,82:3:0 0,15,158:5:0 +17 928 . G 0 . DP=17;I16=7,10,0,0,625,23195,0,0,997,58969,0,0,280,6010,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,9,84:3:0 0,15,150:5:0 +17 929 . T 0 . DP=16;I16=7,9,0,0,580,21580,0,0,937,55369,0,0,277,5925,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,27,248:9:0 0,9,79:3:0 0,12,128:4:0 +17 930 . G 0 . DP=16;I16=7,8,0,0,565,21561,0,0,877,51769,0,0,249,5233,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,24,247:8:0 0,9,82:3:0 0,12,127:4:0 +17 931 . G 0 . DP=16;I16=7,9,0,0,553,19935,0,0,937,55369,0,0,271,5809,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,9,80:3:0 0,12,113:4:0 +17 932 . T 0 . DP=16;I16=7,9,0,0,558,20128,0,0,937,55369,0,0,268,5778,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,27,229:9:0 0,9,89:3:0 0,12,122:4:0 +17 933 . G 0 . DP=16;I16=7,8,0,0,558,20926,0,0,877,51769,0,0,239,5091,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,24,241:8:0 0,9,94:3:0 0,12,116:4:0 +17 934 . C 0 . DP=15;I16=7,8,0,0,548,20256,0,0,877,51769,0,0,261,5673,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,9,83:3:0 0,9,99:3:0 +17 935 . A 0 . DP=15;I16=7,8,0,0,534,19780,0,0,846,49010,0,0,259,5647,0,0;QS=3,0;MQSB=0.720273;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,9,86:3:0 0,9,101:3:0 +17 936 . T 0 . DP=15;I16=7,8,0,0,579,22499,0,0,846,49010,0,0,257,5589,0,0;QS=3,0;MQSB=0.720273;MQ0F=0 PL:DP:DV 0,27,252:9:0 0,9,91:3:0 0,9,100:3:0 +17 937 . G 0 . DP=16;I16=8,7,0,0,550,20650,0,0,846,49010,0,0,232,5022,0,0;QS=3,0;MQSB=0.651439;MQ0F=0 PL:DP:DV 0,24,228:8:0 0,9,84:3:0 0,12,115:4:0 +17 938 . C 0 . DP=16;I16=8,7,0,0,553,20669,0,0,846,49010,0,0,231,5001,0,0;QS=3,0;MQSB=0.651439;MQ0F=0 PL:DP:DV 0,24,234:8:0 0,9,77:3:0 0,12,119:4:0 +17 939 . C 0 . DP=16;I16=8,8,0,0,582,22100,0,0,906,52610,0,0,250,5392,0,0;QS=3,0;MQSB=0.702619;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,9,71:3:0 0,12,115:4:0 +17 940 . T 0 . DP=15;I16=8,7,0,0,583,23339,0,0,846,49010,0,0,248,5320,0,0;QS=3,0;MQSB=0.651439;MQ0F=0 PL:DP:DV 0,27,252:9:0 0,6,71:2:0 0,12,124:4:0 +17 941 . G 0 . DP=14;I16=7,7,0,0,501,18707,0,0,786,45410,0,0,246,5216,0,0;QS=3,0;MQSB=0.714506;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,6,59:2:0 0,9,93:3:0 +17 942 . T 0 . DP=14;I16=7,7,0,0,525,19799,0,0,786,45410,0,0,244,5128,0,0;QS=3,0;MQSB=0.714506;MQ0F=0 PL:DP:DV 0,27,237:9:0 0,6,70:2:0 0,9,94:3:0 +17 943 . A 0 . DP=14;I16=7,7,0,0,545,21399,0,0,786,45410,0,0,242,5056,0,0;QS=3,0;MQSB=0.714506;MQ0F=0 PL:DP:DV 0,27,248:9:0 0,6,71:2:0 0,9,93:3:0 +17 944 . G 0 . DP=14;I16=7,7,0,0,529,20143,0,0,786,45410,0,0,240,5000,0,0;QS=3,0;MQSB=0.714506;MQ0F=0 PL:DP:DV 0,27,249:9:0 0,6,65:2:0 0,9,95:3:0 +17 945 . T 0 . DP=14;I16=7,7,0,0,523,19621,0,0,786,45410,0,0,238,4960,0,0;QS=3,0;MQSB=0.714506;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,6,70:2:0 0,9,95:3:0 +17 946 . C 0 . DP=13;I16=6,6,0,0,455,17581,0,0,666,38210,0,0,223,4739,0,0;QS=3,0;MQSB=0.660716;MQ0F=0 PL:DP:DV 0,24,240:8:0 0,6,56:2:0 0,6,70:2:0 +17 947 . C 0 . DP=14;I16=7,7,0,0,509,19007,0,0,755,42651,0,0,238,4928,0,0;QS=3,0;MQSB=0.925999;MQ0F=0 PL:DP:DV 0,27,251:9:0 0,9,83:3:0 0,6,66:2:0 +17 948 . C 0 . DP=14;I16=7,7,0,0,520,20050,0,0,755,42651,0,0,237,4887,0,0;QS=3,0;MQSB=0.925999;MQ0F=0 PL:DP:DV 0,27,254:9:0 0,9,78:3:0 0,6,69:2:0 +17 949 . A 0 . DP=15;I16=7,8,0,0,547,20705,0,0,815,46251,0,0,236,4864,0,0;QS=3,0;MQSB=0.959011;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,9,90:3:0 0,6,72:2:0 +17 950 . G 0 . DP=15;I16=6,8,0,0,563,22871,0,0,786,45410,0,0,231,4835,0,0;QS=3,0;MQSB=0.740818;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,6,71:2:0 0,6,72:2:0 +17 951 . C 0 . DP=16;I16=7,8,0,0,554,21080,0,0,846,49010,0,0,230,4840,0,0;QS=3,0;MQSB=0.720273;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,65:2:0 0,6,73:2:0 +17 952 . T 0 . DP=16;I16=8,8,0,0,595,22565,0,0,875,49851,0,0,237,4913,0,0;QS=3,0;MQSB=0.934676;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,93:3:0 0,6,73:2:0 +17 953 . A 0 . DP=16;I16=8,8,0,0,567,20515,0,0,875,49851,0,0,237,4921,0,0;QS=3,0;MQSB=0.934676;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,91:3:0 0,6,69:2:0 +17 954 . T 0 . DP=15;I16=7,8,0,0,544,20412,0,0,815,46251,0,0,238,4948,0,0;QS=3,0;MQSB=0.959011;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,9,94:3:0 0,6,69:2:0 +17 955 . T 0 . DP=15;I16=7,8,0,0,543,19953,0,0,815,46251,0,0,239,4993,0,0;QS=3,0;MQSB=0.959011;MQ0F=0 PL:DP:DV 0,30,246:10:0 0,9,95:3:0 0,6,68:2:0 +17 956 . C 0 . DP=15;I16=6,8,0,0,543,21255,0,0,786,45410,0,0,229,4935,0,0;QS=3,0;MQSB=0.740818;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,6,62:2:0 0,6,70:2:0 +17 957 . A 0 . DP=15;I16=7,8,0,0,504,17684,0,0,815,46251,0,0,241,5137,0,0;QS=3,0;MQSB=0.959011;MQ0F=0 PL:DP:DV 0,30,240:10:0 0,9,74:3:0 0,6,67:2:0 +17 958 . C 0 . DP=14;I16=6,8,0,0,505,18981,0,0,755,42651,0,0,243,5235,0,0;QS=3,0;MQSB=0.981425;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,9,78:3:0 0,3,39:1:0 +17 959 . A 0 . DP=14;I16=5,8,0,0,519,20885,0,0,726,41810,0,0,231,5153,0,0;QS=3,0;MQSB=0.765017;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,6,72:2:0 0,3,38:1:0 +17 960 . G 0 . DP=15;I16=6,9,0,0,539,19901,0,0,815,46251,0,0,247,5479,0,0;QS=3,0;MQSB=0.99308;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,106:4:0 0,3,41:1:0 +17 961 . T 0 . DP=14;I16=6,8,0,0,523,19835,0,0,755,42651,0,0,250,5574,0,0;QS=3,0;MQSB=0.981425;MQ0F=0 PL:DP:DV 0,27,248:9:0 0,12,114:4:0 0,3,39:1:0 +17 962 . G 0 . DP=14;I16=5,8,0,0,498,19194,0,0,726,41810,0,0,236,5394,0,0;QS=3,0;MQSB=0.765017;MQ0F=0 PL:DP:DV 0,27,253:9:0 0,9,91:3:0 0,3,36:1:0 +17 963 . C 0 . DP=13;I16=5,8,0,0,500,19610,0,0,695,39051,0,0,256,5754,0,0;QS=3,0;MQSB=0.997325;MQ0F=0 PL:DP:DV 0,24,234:8:0 0,12,118:4:0 0,3,40:1:0 +17 964 . T 0 . DP=13;I16=5,8,0,0,512,20430,0,0,695,39051,0,0,259,5835,0,0;QS=3,0;MQSB=0.997325;MQ0F=0 PL:DP:DV 0,24,227:8:0 0,12,128:4:0 0,3,42:1:0 +17 965 . G 0 . DP=13;I16=4,8,0,0,467,18429,0,0,666,38210,0,0,241,5477,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,228:8:0 0,9,93:3:0 0,3,40:1:0 +17 966 . A 0 . DP=13;I16=4,8,0,0,443,16785,0,0,666,38210,0,0,242,5490,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,212:8:0 0,9,95:3:0 0,3,40:1:0 +17 967 . G 0 . DP=13;I16=4,8,0,0,464,18036,0,0,666,38210,0,0,243,5513,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,230:8:0 0,9,91:3:0 0,3,41:1:0 +17 968 . G 0 . DP=13;I16=4,8,0,0,441,16549,0,0,666,38210,0,0,244,5546,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,218:8:0 0,9,87:3:0 0,3,42:1:0 +17 969 . T 0 . DP=13;I16=4,8,0,0,450,16970,0,0,666,38210,0,0,245,5589,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,220:8:0 0,9,98:3:0 0,3,31:1:0 +17 970 . G 0 . DP=13;I16=4,7,0,0,413,15579,0,0,629,36841,0,0,220,4968,0,0;QS=3,0;MQSB=0.924449;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,6,71:2:0 0,3,33:1:0 +17 971 . G 0 . DP=13;I16=4,8,0,0,459,17711,0,0,666,38210,0,0,245,5609,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,223:8:0 0,9,93:3:0 0,3,38:1:0 +17 972 . G 0 . DP=13;I16=4,8,0,0,446,17192,0,0,666,38210,0,0,245,5637,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,210:8:0 0,9,96:3:0 0,3,39:1:0 +17 973 . A 0 . DP=12;I16=4,7,0,0,402,15018,0,0,606,34610,0,0,246,5676,0,0;QS=3,0;MQSB=0.763675;MQ0F=0 PL:DP:DV 0,21,192:7:0 0,9,89:3:0 0,3,42:1:0 +17 974 . A 0 . DP=12;I16=4,7,0,0,417,16273,0,0,606,34610,0,0,247,5725,0,0;QS=3,0;MQSB=0.763675;MQ0F=0 PL:DP:DV 0,21,198:7:0 0,9,96:3:0 0,3,42:1:0 +17 975 . G 0 . DP=13;I16=4,8,0,0,454,17560,0,0,666,38210,0,0,247,5733,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,213:8:0 0,9,95:3:0 0,3,42:1:0 +17 976 . A 0 . DP=13;I16=4,8,0,0,431,16083,0,0,666,38210,0,0,248,5750,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,227:8:0 0,9,70:3:0 0,3,41:1:0 +17 977 . T 0 . DP=13;I16=4,8,0,0,438,16316,0,0,666,38210,0,0,248,5726,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,210:8:0 0,9,93:3:0 0,3,37:1:0 +17 978 . G 0 . DP=12;I16=4,8,0,0,430,16060,0,0,666,38210,0,0,248,5710,0,0;QS=3,0;MQSB=0.793923;MQ0F=0 PL:DP:DV 0,24,224:8:0 0,9,75:3:0 0,3,40:1:0 +17 979 . C 0 . DP=13;I16=4,8,0,0,453,17461,0,0,689,40441,0,0,223,5077,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,27,232:9:0 0,6,72:2:0 0,3,41:1:0 +17 980 . T 0 . DP=13;I16=4,8,0,0,438,16412,0,0,689,40441,0,0,224,5078,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,27,220:9:0 0,6,76:2:0 0,3,43:1:0 +17 981 . T 0 . DP=13;I16=4,9,0,0,484,18602,0,0,726,41810,0,0,250,5714,0,0;QS=3,0;MQSB=0.826565;MQ0F=0 PL:DP:DV 0,27,224:9:0 0,9,97:3:0 0,3,41:1:0 +17 982 . G 0 . DP=14;I16=4,10,0,0,520,20128,0,0,786,45410,0,0,250,5686,0,0;QS=3,0;MQSB=0.852144;MQ0F=0 PL:DP:DV 0,30,237:10:0 0,9,99:3:0 0,3,40:1:0 +17 983 . A 0 . DP=14;I16=4,10,0,0,570,23360,0,0,786,45410,0,0,251,5671,0,0;QS=3,0;MQSB=0.852144;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,101:3:0 0,3,42:1:0 +17 984 . G 0 . DP=15;I16=4,10,0,0,529,20459,0,0,786,45410,0,0,252,5670,0,0;QS=3,0;MQSB=0.852144;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,9,88:3:0 0,3,43:1:0 +17 985 . C 0 . DP=17;I16=4,13,0,0,580,20280,0,0,966,56210,0,0,261,5747,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,33,246:11:0 0,12,100:4:0 0,6,65:2:0 +17 986 . C A, 0 . DP=17;I16=3,12,0,1,519,18353,13,169,846,49010,60,3600,235,5101,4,16;QS=2.95873,0.0412698,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.921781;BQB=1;MQ0F=0 PL:DP:DV 0,16,197,27,200,201:10:1 0,12,108,12,108,108:4:0 0,6,69,6,69,69:2:0 +17 987 . C 0 . DP=17;I16=4,13,0,0,634,23914,0,0,966,56210,0,0,267,5755,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,107:4:0 0,6,69:2:0 +17 988 . A 0 . DP=17;I16=4,13,0,0,633,24341,0,0,966,56210,0,0,269,5737,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,111:4:0 0,6,82:2:0 +17 989 . G 0 . DP=17;I16=4,13,0,0,635,24149,0,0,966,56210,0,0,271,5739,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,114:4:0 0,6,80:2:0 +17 990 . G 0 . DP=16;I16=4,12,0,0,591,22177,0,0,906,52610,0,0,274,5760,0,0;QS=3,0;MQSB=0.88901;MQ0F=0 PL:DP:DV 0,30,246:10:0 0,12,105:4:0 0,6,83:2:0 +17 991 . A 0 . DP=16;I16=3,11,0,0,548,21542,0,0,809,47641,0,0,227,4549,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,27,232:9:0 0,9,100:3:0 0,6,80:2:0 +17 992 . G 0 . DP=16;I16=4,12,0,0,562,20436,0,0,906,52610,0,0,278,5760,0,0;QS=3,0;MQSB=0.88901;MQ0F=0 PL:DP:DV 0,30,240:10:0 0,12,102:4:0 0,6,76:2:0 +17 993 . T 0 . DP=16;I16=4,12,0,0,564,20752,0,0,906,52610,0,0,280,5790,0,0;QS=3,0;MQSB=0.88901;MQ0F=0 PL:DP:DV 0,30,222:10:0 0,12,121:4:0 0,6,73:2:0 +17 994 . T 0 . DP=17;I16=5,11,0,0,597,22625,0,0,906,52610,0,0,270,5696,0,0;QS=3,0;MQSB=0.851779;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,12,123:4:0 0,9,103:3:0 +17 995 . C 0 . DP=16;I16=4,11,0,0,588,23228,0,0,846,49010,0,0,273,5741,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,24,216:8:0 0,12,119:4:0 0,9,110:3:0 +17 996 . A 0 . DP=16;I16=4,12,0,0,562,20416,0,0,906,52610,0,0,290,6000,0,0;QS=3,0;MQSB=0.88901;MQ0F=0 PL:DP:DV 0,27,207:9:0 0,12,107:4:0 0,9,113:3:0 +17 997 . A 0 . DP=16;I16=4,12,0,0,600,23520,0,0,906,52610,0,0,294,6110,0,0;QS=3,0;MQSB=0.88901;MQ0F=0 PL:DP:DV 0,27,209:9:0 0,12,123:4:0 0,9,121:3:0 +17 998 . G 0 . DP=17;I16=4,13,0,0,603,22299,0,0,966,56210,0,0,298,6240,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,30,226:10:0 0,12,99:4:0 0,9,115:3:0 +17 999 . G 0 . DP=17;I16=4,12,0,0,575,21519,0,0,906,52610,0,0,302,6390,0,0;QS=3,0;MQSB=0.88901;MQ0F=0 PL:DP:DV 0,27,202:9:0 0,12,118:4:0 0,9,111:3:0 +17 1000 . C 0 . DP=17;I16=4,13,0,0,637,24465,0,0,966,56210,0,0,308,6564,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,30,235:10:0 0,12,118:4:0 0,9,109:3:0 +17 1001 . T 0 . DP=17;I16=4,13,0,0,647,24907,0,0,966,56210,0,0,312,6708,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,30,228:10:0 0,12,120:4:0 0,9,122:3:0 +17 1002 . G 0 . DP=17;I16=4,13,0,0,627,23691,0,0,966,56210,0,0,316,6872,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,30,220:10:0 0,12,123:4:0 0,9,109:3:0 +17 1003 . C T, 0 . DP=18;I16=4,13,0,1,633,23953,22,484,966,56210,60,3600,297,6515,21,441;QS=2.9375,0.0625,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.913725;BQB=1;MQ0F=0 PL:DP:DV 0,8,207,27,211,220:10:1 0,15,132,15,132,132:5:0 0,9,102,9,102,102:3:0 +17 1004 . A 0 . DP=19;I16=5,14,0,0,653,23107,0,0,1086,63410,0,0,321,7061,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,231:11:0 0,15,131:5:0 0,9,98:3:0 +17 1005 . A 0 . DP=19;I16=5,14,0,0,670,24380,0,0,1086,63410,0,0,324,7138,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,231:11:0 0,15,132:5:0 0,9,113:3:0 +17 1006 . T 0 . DP=19;I16=4,14,0,0,659,24869,0,0,1026,59810,0,0,327,7237,0,0;QS=3,0;MQSB=0.913725;MQ0F=0 PL:DP:DV 0,30,220:10:0 0,15,134:5:0 0,9,115:3:0 +17 1007 . G 0 . DP=18;I16=4,13,0,0,651,25373,0,0,966,56210,0,0,306,6732,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,27,225:9:0 0,15,138:5:0 0,9,113:3:0 +17 1008 . A 0 . DP=18;I16=4,13,0,0,667,27041,0,0,966,56210,0,0,309,6821,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,27,222:9:0 0,15,147:5:0 0,9,118:3:0 +17 1009 . G 0 . DP=18;I16=4,13,0,0,635,24431,0,0,966,56210,0,0,312,6928,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,27,213:9:0 0,15,139:5:0 0,9,116:3:0 +17 1010 . C 0 . DP=18;I16=4,14,0,0,661,25289,0,0,1026,59810,0,0,339,7629,0,0;QS=3,0;MQSB=0.913725;MQ0F=0 PL:DP:DV 0,30,234:10:0 0,15,126:5:0 0,9,114:3:0 +17 1011 . T 0 . DP=18;I16=4,14,0,0,671,25325,0,0,1026,59810,0,0,339,7623,0,0;QS=3,0;MQSB=0.913725;MQ0F=0 PL:DP:DV 0,30,226:10:0 0,15,131:5:0 0,9,118:3:0 +17 1012 . A 0 . DP=19;I16=5,14,0,0,639,22891,0,0,1063,61179,0,0,339,7633,0,0;QS=3,0;MQSB=0.990403;MQ0F=0 PL:DP:DV 0,30,201:10:0 0,18,154:6:0 0,9,113:3:0 +17 1013 . T 0 . DP=18;I16=5,12,0,0,623,23913,0,0,943,53979,0,0,325,7385,0,0;QS=3,0;MQSB=0.998612;MQ0F=0 PL:DP:DV 0,24,202:8:0 0,18,161:6:0 0,9,115:3:0 +17 1014 . G 0 . DP=18;I16=5,13,0,0,656,24596,0,0,1003,57579,0,0,341,7605,0,0;QS=3,0;MQSB=0.995153;MQ0F=0 PL:DP:DV 0,27,218:9:0 0,18,159:6:0 0,9,113:3:0 +17 1015 . A 0 . DP=18;I16=5,13,0,0,646,23878,0,0,1003,57579,0,0,342,7618,0,0;QS=3,0;MQSB=0.995153;MQ0F=0 PL:DP:DV 0,27,209:9:0 0,18,164:6:0 0,9,109:3:0 +17 1016 . T 0 . DP=17;I16=4,12,0,0,588,22114,0,0,929,54841,0,0,340,7632,0,0;QS=3,0;MQSB=0.971017;MQ0F=0 PL:DP:DV 0,27,212:9:0 0,12,124:4:0 0,9,101:3:0 +17 1017 . T 0 . DP=18;I16=5,13,0,0,635,23433,0,0,1026,59810,0,0,346,7694,0,0;QS=3,0;MQSB=0.942222;MQ0F=0 PL:DP:DV 0,27,213:9:0 0,18,155:6:0 0,9,105:3:0 +17 1018 . G 0 . DP=18;I16=5,13,0,0,650,24550,0,0,1026,59810,0,0,349,7757,0,0;QS=3,0;MQSB=0.942222;MQ0F=0 PL:DP:DV 0,27,215:9:0 0,18,179:6:0 0,9,91:3:0 +17 1019 . C 0 . DP=18;I16=5,12,0,0,555,18561,0,0,966,56210,0,0,327,7213,0,0;QS=3,0;MQSB=0.951229;MQ0F=0 PL:DP:DV 0,24,181:8:0 0,18,143:6:0 0,9,104:3:0 +17 1020 . G 0 . DP=19;I16=6,12,0,0,625,22287,0,0,1026,59810,0,0,332,7402,0,0;QS=3,0;MQSB=0.97296;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,18,157:6:0 0,9,87:3:0 +17 1021 . C 0 . DP=19;I16=5,13,0,0,625,22761,0,0,1026,59810,0,0,332,7326,0,0;QS=3,0;MQSB=0.942222;MQ0F=0 PL:DP:DV 0,27,220:9:0 0,18,153:6:0 0,9,92:3:0 +17 1022 . C 0 . DP=19;I16=6,13,0,0,727,27975,0,0,1086,63410,0,0,360,8034,0,0;QS=3,0;MQSB=0.965977;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,168:6:0 0,9,110:3:0 +17 1023 . A 0 . DP=19;I16=6,12,0,0,647,23997,0,0,1026,59810,0,0,338,7510,0,0;QS=3,0;MQSB=0.97296;MQ0F=0 PL:DP:DV 0,27,216:9:0 0,18,168:6:0 0,9,112:3:0 +17 1024 . C 0 . DP=20;I16=7,13,0,0,729,27471,0,0,1146,67010,0,0,364,8154,0,0;QS=3,0;MQSB=0.980568;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,169:6:0 0,9,106:3:0 +17 1025 . T 0 . DP=20;I16=7,13,0,0,757,29387,0,0,1146,67010,0,0,366,8192,0,0;QS=3,0;MQSB=0.980568;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,181:6:0 0,9,117:3:0 +17 1026 . G 0 . DP=20;I16=7,13,0,0,747,28435,0,0,1146,67010,0,0,367,8201,0,0;QS=3,0;MQSB=0.980568;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,169:6:0 0,9,113:3:0 +17 1027 . C 0 . DP=20;I16=7,13,0,0,720,26688,0,0,1146,67010,0,0,368,8232,0,0;QS=3,0;MQSB=0.980568;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,145:6:0 0,9,110:3:0 +17 1028 . A 0 . DP=19;I16=6,12,0,0,645,23681,0,0,1026,59810,0,0,348,7800,0,0;QS=3,0;MQSB=0.97296;MQ0F=0 PL:DP:DV 0,30,238:10:0 0,15,146:5:0 0,9,99:3:0 +17 1029 . C 0 . DP=19;I16=7,12,0,0,699,26817,0,0,1086,63410,0,0,371,8305,0,0;QS=3,0;MQSB=0.985816;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,138:5:0 0,9,111:3:0 +17 1030 . T 0 . DP=19;I16=7,12,0,0,749,29789,0,0,1086,63410,0,0,371,8293,0,0;QS=3,0;MQSB=0.985816;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,158:5:0 0,9,122:3:0 +17 1031 . T 0 . DP=21;I16=9,12,0,0,748,27726,0,0,1206,70610,0,0,371,8297,0,0;QS=3,0;MQSB=0.997478;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,144:5:0 0,9,113:3:0 +17 1032 . T 0 . DP=21;I16=9,12,0,0,761,28033,0,0,1206,70610,0,0,373,8319,0,0;QS=3,0;MQSB=0.997478;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,156:5:0 0,9,111:3:0 +17 1033 . G 0 . DP=22;I16=10,12,0,0,773,28227,0,0,1266,74210,0,0,375,8361,0,0;QS=3,0;MQSB=0.999457;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,169:6:0 0,9,101:3:0 +17 1034 . G 0 . DP=22;I16=8,12,0,0,703,25617,0,0,1169,69241,0,0,340,7684,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,149:5:0 0,9,102:3:0 +17 1035 . C 0 . DP=21;I16=10,11,0,0,719,26103,0,0,1237,73369,0,0,382,8508,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,163:6:0 0,9,94:3:0 +17 1036 . C 0 . DP=22;I16=11,10,0,0,756,28390,0,0,1237,73369,0,0,360,7938,0,0;QS=3,0;MQSB=0.939898;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,175:6:0 0,12,135:4:0 +17 1037 . T 0 . DP=22;I16=11,11,0,0,839,32737,0,0,1297,76969,0,0,389,8641,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,188:6:0 0,12,138:4:0 +17 1038 . G 0 . DP=21;I16=10,10,0,0,752,28750,0,0,1177,69769,0,0,368,8066,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,184:6:0 0,9,107:3:0 +17 1039 . G 0 . DP=21;I16=10,11,0,0,775,29373,0,0,1237,73369,0,0,397,8761,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,189:6:0 0,9,111:3:0 +17 1040 . A 0 . DP=21;I16=10,11,0,0,759,28007,0,0,1237,73369,0,0,401,8851,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,177:6:0 0,9,107:3:0 +17 1041 . C 0 . DP=21;I16=8,11,0,0,713,27117,0,0,1140,68400,0,0,371,8255,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,155:5:0 0,9,110:3:0 +17 1042 . A 0 . DP=23;I16=12,10,0,0,800,29464,0,0,1297,76969,0,0,384,8466,0,0;QS=3,0;MQSB=0.947103;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,185:6:0 0,15,145:5:0 +17 1043 . A 0 . DP=23;I16=12,11,0,0,850,32160,0,0,1357,80569,0,0,414,9192,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,188:6:0 0,15,159:5:0 +17 1044 . C 0 . DP=23;I16=12,10,0,0,812,30758,0,0,1297,76969,0,0,394,8690,0,0;QS=3,0;MQSB=0.947103;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,181:6:0 0,15,150:5:0 +17 1045 . A 0 . DP=23;I16=12,11,0,0,887,34519,0,0,1357,80569,0,0,424,9460,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,197:6:0 0,15,156:5:0 +17 1046 . G 0 . DP=23;I16=12,11,0,0,862,33240,0,0,1357,80569,0,0,428,9576,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,183:6:0 0,15,158:5:0 +17 1047 . A 0 . DP=23;I16=12,11,0,0,890,34804,0,0,1357,80569,0,0,432,9712,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,198:6:0 0,15,165:5:0 +17 1048 . G 0 . DP=23;I16=12,10,0,0,846,33054,0,0,1297,76969,0,0,411,9243,0,0;QS=3,0;MQSB=0.947103;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,195:6:0 0,15,156:5:0 +17 1049 . C 0 . DP=22;I16=12,10,0,0,808,30644,0,0,1297,76969,0,0,441,10043,0,0;QS=3,0;MQSB=0.947103;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,182:6:0 0,15,160:5:0 +17 1050 . A 0 . DP=22;I16=11,10,0,0,808,31334,0,0,1237,73369,0,0,430,9940,0,0;QS=3,0;MQSB=0.939898;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,193:6:0 0,12,138:4:0 +17 1051 . A 0 . DP=21;I16=11,9,0,0,731,27495,0,0,1177,69769,0,0,423,9621,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,18,187:6:0 0,15,150:5:0 +17 1052 . A 0 . DP=21;I16=11,9,0,0,759,29327,0,0,1177,69769,0,0,427,9747,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,27,247:9:0 0,18,190:6:0 0,15,150:5:0 +17 1053 . A 0 . DP=21;I16=11,8,0,0,674,25210,0,0,1117,66169,0,0,406,9264,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,24,224:8:0 0,18,161:6:0 0,15,149:5:0 +17 1054 . C 0 . DP=21;I16=11,10,0,0,791,30157,0,0,1237,73369,0,0,459,10623,0,0;QS=3,0;MQSB=0.939898;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,189:6:0 0,15,153:5:0 +17 1055 . C 0 . DP=22;I16=12,10,0,0,818,31448,0,0,1297,76969,0,0,462,10750,0,0;QS=3,0;MQSB=0.947103;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,191:6:0 0,15,157:5:0 +17 1056 . C 0 . DP=22;I16=12,9,0,0,793,31265,0,0,1237,73369,0,0,441,10271,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,195:6:0 0,15,161:5:0 +17 1057 . T 0 . DP=23;I16=12,10,0,0,821,31667,0,0,1297,76969,0,0,467,10911,0,0;QS=3,0;MQSB=0.947103;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,196:6:0 0,15,159:5:0 +17 1058 . G 0 . DP=23;I16=12,11,0,0,863,32871,0,0,1357,80569,0,0,493,11569,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,197:7:0 0,15,155:5:0 +17 1059 . T 0 . DP=23;I16=12,10,0,0,797,29803,0,0,1297,76969,0,0,468,10944,0,0;QS=3,0;MQSB=0.947103;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,21,202:7:0 0,15,152:5:0 +17 1060 . C 0 . DP=23;I16=12,11,0,0,829,31041,0,0,1357,80569,0,0,492,11536,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,178:7:0 0,15,163:5:0 +17 1061 . T 0 . DP=22;I16=12,9,0,0,810,31840,0,0,1237,73369,0,0,465,10797,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,175:5:0 0,15,158:5:0 +17 1062 . C A, 0 . DP=22;I16=12,9,0,1,826,32780,33,1089,1237,73369,60,3600,462,10652,25,625;QS=2.85398,0.146018,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.947103;BQB=1;MQ0F=0 PL:DP:DV 0,33,255,33,255,255:11:0 15,0,151,30,154,176:6:1 0,15,164,15,164,164:5:0 +17 1063 . T 0 . DP=22;I16=12,9,0,0,820,32460,0,0,1237,73369,0,0,459,10525,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,183:6:0 0,15,166:5:0 +17 1064 . A 0 . DP=23;I16=12,9,0,0,793,30355,0,0,1237,73369,0,0,464,10752,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,180:6:0 0,15,162:5:0 +17 1065 . A 0 . DP=23;I16=12,9,0,0,814,31978,0,0,1237,73369,0,0,462,10694,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,186:6:0 0,15,174:5:0 +17 1066 . A 0 . DP=27;I16=15,9,0,0,890,34378,0,0,1417,84169,0,0,460,10652,0,0;QS=3,0;MQSB=0.96464;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,198:7:0 0,18,181:6:0 +17 1067 . A 0 . DP=27;I16=15,10,0,0,913,35031,0,0,1477,87769,0,0,470,10600,0,0;QS=3,0;MQSB=0.962269;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,208:7:0 0,18,182:6:0 +17 1068 . A 0 . DP=27;I16=15,9,0,0,898,34580,0,0,1417,84169,0,0,456,10342,0,0;QS=3,0;MQSB=0.96464;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,24,218:8:0 0,18,181:6:0 +17 1069 . A 0 . DP=28;I16=16,10,0,0,914,33888,0,0,1537,91369,0,0,481,10925,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,207:8:0 0,21,177:7:0 +17 1070 . A 0 . DP=28;I16=15,11,0,0,955,36445,0,0,1537,91369,0,0,467,10351,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,223:8:0 0,21,188:7:0 +17 1071 . G 0 . DP=28;I16=16,10,0,0,974,37570,0,0,1537,91369,0,0,466,10284,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,192:7:0 0,21,191:7:0 +17 1072 . A 0 . DP=28;I16=16,11,0,0,1007,38205,0,0,1597,94969,0,0,490,10868,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,239:8:0 0,21,195:7:0 +17 1073 . A 0 . DP=28;I16=16,10,0,0,976,37822,0,0,1537,91369,0,0,463,10177,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,24,236:8:0 0,21,199:7:0 +17 1074 . A 0 . DP=28;I16=16,11,0,0,1003,38097,0,0,1597,94969,0,0,484,10664,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,232:8:0 0,21,203:7:0 +17 1075 . A 0 . DP=28;I16=16,10,0,0,964,36762,0,0,1537,91369,0,0,476,10564,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,222:8:0 0,21,200:7:0 +17 1076 . G 0 . DP=28;I16=16,10,0,0,966,37048,0,0,1537,91369,0,0,476,10536,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,209:8:0 0,21,183:7:0 +17 1077 . A 0 . DP=29;I16=17,11,0,0,1038,39240,0,0,1657,98569,0,0,480,10548,0,0;QS=3,0;MQSB=0.967085;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,231:8:0 0,24,209:8:0 +17 1078 . A 0 . DP=29;I16=17,11,0,0,1053,40425,0,0,1657,98569,0,0,480,10562,0,0;QS=3,0;MQSB=0.967085;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,234:8:0 0,24,214:8:0 +17 1079 . A 0 . DP=28;I16=17,10,0,0,1019,39007,0,0,1597,94969,0,0,479,10505,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,223:8:0 0,24,206:8:0 +17 1080 . A 0 . DP=29;I16=18,10,0,0,1049,40827,0,0,1657,98569,0,0,478,10478,0,0;QS=3,0;MQSB=0.971673;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,246:9:0 0,24,218:8:0 +17 1081 . G 0 . DP=30;I16=19,8,0,0,988,37392,0,0,1597,94969,0,0,436,9550,0,0;QS=3,0;MQSB=0.977696;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,210:8:0 0,27,210:9:0 +17 1082 . A 0 . DP=30;I16=20,7,0,0,989,37109,0,0,1597,94969,0,0,438,9564,0,0;QS=3,0;MQSB=0.981425;MQ0F=0 PL:DP:DV 0,27,224:9:0 0,27,226:9:0 0,27,217:9:0 +17 1083 . A 0 . DP=30;I16=20,8,0,0,1039,39827,0,0,1657,98569,0,0,455,9803,0,0;QS=3,0;MQSB=0.979523;MQ0F=0 PL:DP:DV 0,30,246:10:0 0,27,233:9:0 0,27,217:9:0 +17 1084 . A 0 . DP=31;I16=21,8,0,0,1049,39097,0,0,1717,102169,0,0,457,9849,0,0;QS=3,0;MQSB=0.981133;MQ0F=0 PL:DP:DV 0,33,253:11:0 0,27,226:9:0 0,27,215:9:0 +17 1085 . A 0 . DP=30;I16=21,8,0,0,1052,39534,0,0,1717,102169,0,0,486,10552,0,0;QS=3,0;MQSB=0.981133;MQ0F=0 PL:DP:DV 0,30,232:10:0 0,30,247:10:0 0,27,214:9:0 +17 1086 . A 0 . DP=28;I16=21,6,0,0,969,36223,0,0,1597,94969,0,0,492,10660,0,0;QS=3,0;MQSB=0.98481;MQ0F=0 PL:DP:DV 0,30,219:10:0 0,27,236:9:0 0,24,179:8:0 +17 1087 . C 0 . DP=28;I16=22,6,0,0,984,36046,0,0,1657,98569,0,0,498,10796,0,0;QS=3,0;MQSB=0.985992;MQ0F=0 PL:DP:DV 0,30,234:10:0 0,27,229:9:0 0,27,173:9:0 +17 1088 . T 0 . DP=29;I16=23,6,0,0,1133,45203,0,0,1717,102169,0,0,503,10863,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,30,250:10:0 0,27,198:9:0 +17 1089 . C 0 . DP=29;I16=23,6,0,0,1093,42347,0,0,1717,102169,0,0,509,10965,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,30,237:10:0 0,27,188:9:0 +17 1090 . A 0 . DP=29;I16=23,6,0,0,1061,39845,0,0,1717,102169,0,0,515,11103,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,221:10:0 0,30,250:10:0 0,27,183:9:0 +17 1091 . C 0 . DP=29;I16=23,6,0,0,1063,39713,0,0,1717,102169,0,0,521,11277,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,30,244:10:0 0,27,177:9:0 +17 1092 . T 0 . DP=29;I16=23,6,0,0,1121,44489,0,0,1717,102169,0,0,524,11334,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,244:10:0 0,30,251:10:0 0,27,198:9:0 +17 1093 . G 0 . DP=29;I16=23,6,0,0,1085,41377,0,0,1717,102169,0,0,526,11372,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,30,243:10:0 0,27,184:9:0 +17 1094 . G 0 . DP=29;I16=22,6,0,0,1018,38808,0,0,1657,98569,0,0,521,11393,0,0;QS=3,0;MQSB=0.985992;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,30,232:10:0 0,24,185:8:0 +17 1095 . A 0 . DP=28;I16=22,6,0,0,1023,38551,0,0,1657,98569,0,0,529,11443,0,0;QS=3,0;MQSB=0.985992;MQ0F=0 PL:DP:DV 0,30,236:10:0 0,30,244:10:0 0,24,178:8:0 +17 1096 . T 0 . DP=30;I16=24,5,0,0,1020,37168,0,0,1717,102169,0,0,505,10849,0,0;QS=3,0;MQSB=0.989637;MQ0F=0 PL:DP:DV 0,33,234:11:0 0,27,220:9:0 0,27,178:9:0 +17 1097 . A 0 . DP=30;I16=24,6,0,0,1056,38166,0,0,1777,105769,0,0,533,11537,0,0;QS=3,0;MQSB=0.987976;MQ0F=0 PL:DP:DV 0,33,230:11:0 0,30,237:10:0 0,27,177:9:0 +17 1098 . T 0 . DP=29;I16=24,5,0,0,1081,40557,0,0,1717,102169,0,0,537,11633,0,0;QS=3,0;MQSB=0.989637;MQ0F=0 PL:DP:DV 0,30,210:10:0 0,30,251:10:0 0,27,186:9:0 +17 1099 . G 0 . DP=29;I16=24,5,0,0,1091,41719,0,0,1717,102169,0,0,540,11712,0,0;QS=3,0;MQSB=0.989637;MQ0F=0 PL:DP:DV 0,30,229:10:0 0,30,242:10:0 0,27,182:9:0 +17 1100 . A 0 . DP=29;I16=24,5,0,0,1106,42976,0,0,1717,102169,0,0,543,11825,0,0;QS=3,0;MQSB=0.989637;MQ0F=0 PL:DP:DV 0,30,210:10:0 0,30,255:10:0 0,27,191:9:0 +17 1101 . A 0 . DP=29;I16=24,5,0,0,1154,46420,0,0,1717,102169,0,0,545,11921,0,0;QS=3,0;MQSB=0.989637;MQ0F=0 PL:DP:DV 0,30,222:10:0 0,30,255:10:0 0,27,198:9:0 +17 1102 . T 0 . DP=29;I16=24,4,0,0,1046,39520,0,0,1657,98569,0,0,522,11424,0,0;QS=3,0;MQSB=0.991416;MQ0F=0 PL:DP:DV 0,30,210:10:0 0,27,233:9:0 0,27,186:9:0 +17 1103 . G 0 . DP=30;I16=24,6,0,0,1134,43486,0,0,1777,105769,0,0,548,12158,0,0;QS=3,0;MQSB=0.987976;MQ0F=0 PL:DP:DV 0,30,223:10:0 0,30,255:10:0 0,30,222:10:0 +17 1104 . A 0 . DP=28;I16=23,5,0,0,1089,43067,0,0,1657,98569,0,0,552,12296,0,0;QS=3,0;MQSB=0.988819;MQ0F=0 PL:DP:DV 0,27,213:9:0 0,27,233:9:0 0,30,233:10:0 +17 1105 . T 0 . DP=28;I16=23,5,0,0,1035,38743,0,0,1657,98569,0,0,556,12462,0,0;QS=3,0;MQSB=0.988819;MQ0F=0 PL:DP:DV 0,27,203:9:0 0,27,227:9:0 0,30,222:10:0 +17 1106 . A 0 . DP=29;I16=23,5,0,0,1003,36715,0,0,1657,98569,0,0,532,11882,0,0;QS=3,0;MQSB=0.988819;MQ0F=0 PL:DP:DV 0,30,227:10:0 0,24,198:8:0 0,30,217:10:0 +17 1107 . C 0 . DP=29;I16=23,6,0,0,1093,41509,0,0,1717,102169,0,0,558,12532,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,244:10:0 0,27,233:9:0 0,30,220:10:0 +17 1108 . A 0 . DP=29;I16=23,6,0,0,1138,44908,0,0,1717,102169,0,0,558,12536,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,239:10:0 0,27,253:9:0 0,30,227:10:0 +17 1109 . G 0 . DP=29;I16=23,6,0,0,1140,45200,0,0,1717,102169,0,0,557,12519,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,27,240:9:0 0,30,224:10:0 +17 1110 . G 0 . DP=29;I16=23,6,0,0,1086,41054,0,0,1717,102169,0,0,555,12481,0,0;QS=3,0;MQSB=0.987041;MQ0F=0 PL:DP:DV 0,30,242:10:0 0,27,229:9:0 0,30,224:10:0 +17 1111 . T 0 . DP=29;I16=22,6,0,0,1025,37919,0,0,1680,100800,0,0,552,12470,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,227:10:0 0,24,227:8:0 0,30,211:10:0 +17 1112 . T 0 . DP=28;I16=22,6,0,0,1034,38986,0,0,1680,100800,0,0,550,12440,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,226:10:0 0,24,221:8:0 0,30,221:10:0 +17 1113 . G 0 . DP=28;I16=23,5,0,0,1085,42273,0,0,1680,100800,0,0,548,12386,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,202:7:0 0,33,222:11:0 +17 1114 . A 0 . DP=28;I16=23,5,0,0,1079,42279,0,0,1680,100800,0,0,546,12306,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,235:10:0 0,21,209:7:0 0,33,238:11:0 +17 1115 . G 0 . DP=28;I16=23,5,0,0,1114,44550,0,0,1680,100800,0,0,544,12250,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,208:7:0 0,33,234:11:0 +17 1116 . G 0 . DP=29;I16=24,5,0,0,1059,39531,0,0,1740,104400,0,0,542,12218,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,236:10:0 0,24,204:8:0 0,33,226:11:0 +17 1117 . A 0 . DP=29;I16=24,5,0,0,1124,43896,0,0,1740,104400,0,0,541,12211,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,235:10:0 0,24,227:8:0 0,33,234:11:0 +17 1118 . T 0 . DP=29;I16=24,4,0,0,1100,44802,0,0,1680,100800,0,0,539,12131,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,230:10:0 0,21,188:7:0 0,33,248:11:0 +17 1119 . C 0 . DP=29;I16=23,4,0,0,1078,44864,0,0,1620,97200,0,0,526,11958,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,224:9:0 0,21,191:7:0 0,33,255:11:0 +17 1120 . C 0 . DP=29;I16=23,5,0,0,1113,46071,0,0,1680,100800,0,0,536,12054,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,24,214:8:0 0,33,255:11:0 +17 1121 . A 0 . DP=30;I16=24,5,0,0,1167,48549,0,0,1740,104400,0,0,536,12056,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,24,220:8:0 0,36,255:12:0 +17 1122 . T 0 . DP=32;I16=26,5,0,0,1235,50967,0,0,1860,111600,0,0,535,11985,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,230:10:0 0,27,238:9:0 0,36,255:12:0 +17 1123 . T 0 . DP=32;I16=26,5,0,0,1219,50121,0,0,1860,111600,0,0,535,11893,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,221:10:0 0,27,236:9:0 0,36,255:12:0 +17 1124 . A 0 . DP=31;I16=25,5,0,0,1187,48827,0,0,1800,108000,0,0,536,11832,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,218:9:0 0,27,235:9:0 0,36,255:12:0 +17 1125 . T 0 . DP=31;I16=25,5,0,0,1211,51001,0,0,1800,108000,0,0,537,11801,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,27,235:9:0 0,36,255:12:0 +17 1126 . C 0 . DP=31;I16=25,5,0,0,1225,52001,0,0,1800,108000,0,0,538,11800,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,234:9:0 0,27,241:9:0 0,36,255:12:0 +17 1127 . T 0 . DP=31;I16=25,5,0,0,1257,55245,0,0,1800,108000,0,0,539,11829,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,231:9:0 0,27,252:9:0 0,36,255:12:0 +17 1128 . G 0 . DP=31;I16=25,5,0,0,1217,51743,0,0,1800,108000,0,0,540,11888,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,236:9:0 0,27,229:9:0 0,36,255:12:0 +17 1129 . A G, 0 . DP=31;I16=24,4,0,1,1101,45631,32,1024,1680,100800,60,3600,514,11300,25,625;QS=2.93535,0.0646465,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,24,204,24,204,204:8:0 0,27,229,27,229,229:9:0 0,4,198,33,201,219:12:1 +17 1130 . A 0 . DP=31;I16=25,5,0,0,1189,49509,0,0,1800,108000,0,0,539,11943,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,215:9:0 0,27,236:9:0 0,36,255:12:0 +17 1131 . A 0 . DP=29;I16=23,5,0,0,1156,49362,0,0,1680,100800,0,0,540,11988,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,206:7:0 0,27,250:9:0 0,36,255:12:0 +17 1132 . T 0 . DP=29;I16=23,5,0,0,1123,47359,0,0,1680,100800,0,0,540,12008,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,198:7:0 0,27,229:9:0 0,36,255:12:0 +17 1133 . G 0 . DP=30;I16=23,5,0,0,1148,48796,0,0,1680,100800,0,0,540,12052,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,214:7:0 0,27,232:9:0 0,36,255:12:0 +17 1134 . C 0 . DP=29;I16=22,6,0,0,1162,50224,0,0,1680,100800,0,0,547,12155,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,209:7:0 0,27,254:9:0 0,36,255:12:0 +17 1135 . T 0 . DP=29;I16=22,6,0,0,1214,55020,0,0,1680,100800,0,0,549,12257,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,209:7:0 0,27,255:9:0 0,36,255:12:0 +17 1136 . T 0 . DP=29;I16=22,6,0,0,1148,49270,0,0,1680,100800,0,0,551,12383,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,200:7:0 0,27,255:9:0 0,36,255:12:0 +17 1137 . G 0 . DP=28;I16=21,6,0,0,1087,46051,0,0,1620,97200,0,0,554,12532,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,214:7:0 0,27,234:9:0 0,33,254:11:0 +17 1138 . G 0 . DP=28;I16=21,6,0,0,1040,42504,0,0,1620,97200,0,0,557,12703,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,197:7:0 0,27,234:9:0 0,33,246:11:0 +17 1139 . A 0 . DP=28;I16=21,6,0,0,1103,47389,0,0,1620,97200,0,0,559,12845,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,200:7:0 0,27,254:9:0 0,33,255:11:0 +17 1140 . C 0 . DP=28;I16=21,6,0,0,1072,44372,0,0,1620,97200,0,0,561,13007,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,214:7:0 0,27,234:9:0 0,33,250:11:0 +17 1141 . C 0 . DP=28;I16=21,6,0,0,1106,47298,0,0,1620,97200,0,0,562,13140,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,212:7:0 0,27,245:9:0 0,33,255:11:0 +17 1142 . A 0 . DP=28;I16=21,6,0,0,1114,47788,0,0,1620,97200,0,0,560,13146,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,212:7:0 0,27,255:9:0 0,33,251:11:0 +17 1143 . G 0 . DP=26;I16=19,7,0,0,1041,42249,0,0,1560,93600,0,0,585,13799,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,222:7:0 0,27,249:9:0 0,30,253:10:0 +17 1144 . A 0 . DP=26;I16=19,7,0,0,1018,40154,0,0,1560,93600,0,0,585,13847,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,205:7:0 0,27,250:9:0 0,30,255:10:0 +17 1145 . T 0 . DP=26;I16=19,7,0,0,1016,39852,0,0,1560,93600,0,0,584,13866,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,206:7:0 0,27,250:9:0 0,30,249:10:0 +17 1146 . G 0 . DP=26;I16=19,7,0,0,1011,39743,0,0,1560,93600,0,0,582,13856,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,210:7:0 0,27,246:9:0 0,30,254:10:0 +17 1147 . T 0 . DP=27;I16=20,6,0,0,1010,39730,0,0,1560,93600,0,0,579,13815,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,207:8:0 0,24,234:8:0 0,30,255:10:0 +17 1148 . T 0 . DP=26;I16=20,6,0,0,1002,39214,0,0,1560,93600,0,0,576,13690,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,196:8:0 0,24,237:8:0 0,30,255:10:0 +17 1149 . T 0 . DP=26;I16=20,6,0,0,1022,40532,0,0,1560,93600,0,0,573,13579,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,205:8:0 0,24,231:8:0 0,30,255:10:0 +17 1150 . T 0 . DP=26;I16=20,6,0,0,1032,41212,0,0,1560,93600,0,0,569,13433,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,208:8:0 0,24,236:8:0 0,30,255:10:0 +17 1151 . G 0 . DP=26;I16=20,6,0,0,1021,40285,0,0,1560,93600,0,0,565,13303,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,220:8:0 0,24,231:8:0 0,30,248:10:0 +17 1152 . A 0 . DP=27;I16=20,7,0,0,1040,40772,0,0,1620,97200,0,0,561,13189,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,202:8:0 0,24,230:8:0 0,33,255:11:0 +17 1153 . A 0 . DP=27;I16=20,7,0,0,1039,40717,0,0,1620,97200,0,0,557,13043,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,202:8:0 0,24,233:8:0 0,33,255:11:0 +17 1154 . T 0 . DP=28;I16=21,7,0,0,1073,41861,0,0,1680,100800,0,0,552,12866,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,212:9:0 0,24,236:8:0 0,33,255:11:0 +17 1155 . T 0 . DP=27;I16=20,7,0,0,1074,43046,0,0,1620,97200,0,0,549,12707,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,211:8:0 0,24,236:8:0 0,33,255:11:0 +17 1156 . T 0 . DP=28;I16=19,8,0,0,1065,42533,0,0,1620,97200,0,0,520,11892,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,210:8:0 0,24,239:8:0 0,33,255:11:0 +17 1157 . T 0 . DP=28;I16=20,8,0,0,1094,43108,0,0,1680,100800,0,0,541,12299,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,230:9:0 0,24,230:8:0 0,33,255:11:0 +17 1158 . G 0 . DP=28;I16=20,8,0,0,1098,43584,0,0,1680,100800,0,0,536,12056,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,24,224:8:0 0,33,255:11:0 +17 1159 . G 0 . DP=28;I16=20,8,0,0,1096,43222,0,0,1680,100800,0,0,530,11790,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,249:9:0 0,24,229:8:0 0,33,255:11:0 +17 1160 . A 0 . DP=30;I16=20,10,0,0,1146,44510,0,0,1800,108000,0,0,524,11552,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,229:9:0 0,24,242:8:0 0,39,255:13:0 +17 1161 . T 0 . DP=30;I16=20,10,0,0,1136,43548,0,0,1800,108000,0,0,520,11344,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,221:9:0 0,24,230:8:0 0,39,255:13:0 +17 1162 . T 0 . DP=30;I16=20,10,0,0,1147,44365,0,0,1800,108000,0,0,516,11168,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,232:9:0 0,24,229:8:0 0,39,255:13:0 +17 1163 . T 0 . DP=31;I16=20,11,0,0,1176,45394,0,0,1860,111600,0,0,511,10975,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,24,231:8:0 0,39,255:13:0 +17 1164 . T 0 . DP=31;I16=20,11,0,0,1166,44864,0,0,1860,111600,0,0,506,10768,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,235:10:0 0,24,234:8:0 0,39,255:13:0 +17 1165 . T 0 . DP=31;I16=20,11,0,0,1189,46635,0,0,1860,111600,0,0,501,10599,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,240:10:0 0,24,231:8:0 0,39,255:13:0 +17 1166 . T 0 . DP=30;I16=19,11,0,0,1137,43791,0,0,1800,108000,0,0,497,10467,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,231:9:0 0,24,228:8:0 0,39,255:13:0 +17 1167 . C 0 . DP=28;I16=17,11,0,0,1114,44588,0,0,1680,100800,0,0,495,10369,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,21,216:7:0 0,36,255:12:0 +17 1168 . A 0 . DP=28;I16=17,11,0,0,1074,41862,0,0,1680,100800,0,0,493,10303,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,21,203:7:0 0,36,255:12:0 +17 1169 . T 0 . DP=28;I16=17,11,0,0,1089,42589,0,0,1680,100800,0,0,491,10269,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,247:9:0 0,21,212:7:0 0,36,255:12:0 +17 1170 . A 0 . DP=27;I16=16,11,0,0,1033,39891,0,0,1620,97200,0,0,490,10266,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,21,214:7:0 0,33,255:11:0 +17 1171 . T 0 . DP=28;I16=17,11,0,0,1086,42472,0,0,1680,100800,0,0,488,10244,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,249:9:0 0,24,223:8:0 0,33,255:11:0 +17 1172 . T 0 . DP=28;I16=17,11,0,0,1086,42598,0,0,1680,100800,0,0,486,10206,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,235:9:0 0,24,228:8:0 0,33,255:11:0 +17 1173 . T 0 . DP=29;I16=18,11,0,0,1126,44348,0,0,1740,104400,0,0,483,10153,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,27,241:9:0 0,33,255:11:0 +17 1174 . T 0 . DP=29;I16=18,11,0,0,1098,42352,0,0,1740,104400,0,0,481,10135,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,230:9:0 0,27,238:9:0 0,33,255:11:0 +17 1175 . G 0 . DP=28;I16=18,10,0,0,1063,40975,0,0,1680,100800,0,0,480,10152,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,234:8:0 0,27,234:9:0 0,33,255:11:0 +17 1176 . T 0 . DP=28;I16=18,10,0,0,1045,39823,0,0,1680,100800,0,0,479,10203,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,27,233:9:0 0,33,255:11:0 +17 1177 . A 0 . DP=28;I16=18,10,0,0,1040,39006,0,0,1680,100800,0,0,478,10288,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,220:8:0 0,27,228:9:0 0,33,255:11:0 +17 1178 . A 0 . DP=27;I16=17,10,0,0,1006,38238,0,0,1620,97200,0,0,477,10355,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,27,227:9:0 0,30,255:10:0 +17 1179 . T 0 . DP=27;I16=17,10,0,0,1012,38396,0,0,1620,97200,0,0,475,10403,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,223:8:0 0,27,224:9:0 0,30,255:10:0 +17 1180 . C 0 . DP=27;I16=16,10,0,0,1006,39508,0,0,1560,93600,0,0,469,10423,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,222:7:0 0,27,224:9:0 0,30,255:10:0 +17 1181 . T 0 . DP=26;I16=16,10,0,0,1021,40581,0,0,1560,93600,0,0,469,10441,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,236:8:0 0,24,229:8:0 0,30,255:10:0 +17 1182 . T 0 . DP=26;I16=14,11,0,0,939,35915,0,0,1500,90000,0,0,457,10347,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,236:9:0 0,21,209:7:0 0,27,255:9:0 +17 1183 . T 0 . DP=25;I16=13,11,0,0,899,34555,0,0,1440,86400,0,0,455,10341,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,18,192:6:0 0,27,255:9:0 +17 1184 . G 0 . DP=24;I16=13,11,0,0,916,35398,0,0,1440,86400,0,0,465,10479,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,234:8:0 0,21,201:7:0 0,27,255:9:0 +17 1185 . C 0 . DP=24;I16=13,11,0,0,908,35014,0,0,1440,86400,0,0,465,10541,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,246:8:0 0,21,191:7:0 0,27,250:9:0 +17 1186 . A 0 . DP=24;I16=13,11,0,0,946,37648,0,0,1440,86400,0,0,463,10525,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,240:8:0 0,21,205:7:0 0,27,255:9:0 +17 1187 . G 0 . DP=25;I16=14,11,0,0,908,33870,0,0,1500,90000,0,0,461,10529,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,21,205:7:0 0,27,240:9:0 +17 1188 . T 0 . DP=25;I16=14,11,0,0,886,32138,0,0,1500,90000,0,0,461,10553,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,21,196:7:0 0,24,216:8:0 +17 1189 . A 0 . DP=25;I16=14,11,0,0,920,34392,0,0,1500,90000,0,0,461,10497,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,174:6:0 0,27,252:9:0 +17 1190 . T 0 . DP=26;I16=14,12,0,0,960,35876,0,0,1560,93600,0,0,462,10462,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,185:6:0 0,27,252:9:0 +17 1191 . A 0 . DP=26;I16=14,12,0,0,928,33922,0,0,1560,93600,0,0,464,10450,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,173:6:0 0,27,245:9:0 +17 1192 . T 0 . DP=26;I16=14,12,0,0,981,37505,0,0,1560,93600,0,0,465,10413,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,191:6:0 0,27,255:9:0 +17 1193 . T 0 . DP=26;I16=14,12,0,0,976,37054,0,0,1560,93600,0,0,466,10402,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,191:6:0 0,27,255:9:0 +17 1194 . T 0 . DP=26;I16=14,12,0,0,951,35219,0,0,1560,93600,0,0,466,10368,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,178:6:0 0,27,249:9:0 +17 1195 . A 0 . DP=26;I16=14,12,0,0,917,33253,0,0,1560,93600,0,0,466,10362,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,177:6:0 0,27,235:9:0 +17 1196 . C 0 . DP=25;I16=13,12,0,0,921,34209,0,0,1500,90000,0,0,466,10334,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,187:6:0 0,27,236:9:0 +17 1197 . C 0 . DP=24;I16=12,12,0,0,906,34862,0,0,1440,86400,0,0,464,10184,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,186:6:0 0,24,233:8:0 +17 1198 . A 0 . DP=24;I16=12,12,0,0,937,36815,0,0,1440,86400,0,0,461,10013,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,190:6:0 0,24,245:8:0 +17 1199 . G 0 . DP=24;I16=12,12,0,0,879,33035,0,0,1440,86400,0,0,457,9821,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,163:6:0 0,24,221:8:0 +17 1200 . T 0 . DP=24;I16=11,12,0,0,895,35141,0,0,1380,82800,0,0,428,9032,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,176:5:0 0,24,247:8:0 +17 1201 . T 0 . DP=24;I16=12,12,0,0,889,33727,0,0,1440,86400,0,0,449,9521,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,177:6:0 0,24,238:8:0 +17 1202 . C 0 . DP=25;I16=13,12,0,0,929,35121,0,0,1500,90000,0,0,445,9413,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,175:6:0 0,24,230:8:0 +17 1203 . A 0 . DP=25;I16=13,12,0,0,943,36107,0,0,1500,90000,0,0,442,9334,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,184:6:0 0,24,241:8:0 +17 1204 . G 0 . DP=24;I16=13,11,0,0,876,33106,0,0,1440,86400,0,0,439,9235,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,174:6:0 0,21,218:7:0 +17 1205 . C 0 . DP=24;I16=13,11,0,0,891,33869,0,0,1440,86400,0,0,436,9166,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,176:6:0 0,21,217:7:0 +17 1206 . A 0 . DP=23;I16=13,10,0,0,846,31744,0,0,1380,82800,0,0,434,9126,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,179:6:0 0,21,212:7:0 +17 1207 . T 0 . DP=23;I16=13,9,0,0,819,30877,0,0,1320,79200,0,0,407,8489,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,254:10:0 0,18,189:6:0 0,18,194:6:0 +17 1208 . C 0 . DP=24;I16=14,10,0,0,910,35236,0,0,1440,86400,0,0,429,9079,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,190:7:0 0,21,217:7:0 +17 1209 . C T, 0 . DP=24;I16=14,9,0,1,869,33481,21,441,1380,82800,60,3600,408,8710,19,361;QS=2.91393,0.0860656,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,30,255,30,255,255:10:0 0,0,153,18,156,166:7:1 0,21,209,21,209,209:7:0 +17 1210 . C 0 . DP=24;I16=14,10,0,0,915,35713,0,0,1440,86400,0,0,425,9091,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,199:7:0 0,21,209:7:0 +17 1211 . T 0 . DP=24;I16=14,10,0,0,905,34669,0,0,1440,86400,0,0,423,9139,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,213:7:0 0,21,214:7:0 +17 1212 . A 0 . DP=24;I16=14,10,0,0,850,30690,0,0,1440,86400,0,0,421,9215,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,246:10:0 0,21,190:7:0 0,21,204:7:0 +17 1213 . A 0 . DP=24;I16=14,10,0,0,852,31192,0,0,1440,86400,0,0,418,9268,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,21,197:7:0 0,21,195:7:0 +17 1214 . C 0 . DP=23;I16=13,10,0,0,851,32099,0,0,1380,82800,0,0,415,9295,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,186:7:0 0,18,184:6:0 +17 1215 . T 0 . DP=23;I16=13,9,0,0,839,32475,0,0,1320,79200,0,0,386,8668,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,211:7:0 0,15,172:5:0 +17 1216 . C 0 . DP=23;I16=13,10,0,0,863,32923,0,0,1380,82800,0,0,406,9260,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,196:7:0 0,18,172:6:0 +17 1217 . A 0 . DP=22;I16=12,10,0,0,820,30926,0,0,1320,79200,0,0,402,9244,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,172:6:0 0,18,191:6:0 +17 1218 . A 0 . DP=22;I16=12,10,0,0,764,27286,0,0,1320,79200,0,0,398,9244,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,145:6:0 0,18,184:6:0 +17 1219 . A 0 . DP=21;I16=12,9,0,0,803,31119,0,0,1260,75600,0,0,395,9259,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,175:6:0 0,15,173:5:0 +17 1220 . A 0 . DP=21;I16=12,9,0,0,752,27700,0,0,1260,75600,0,0,392,9288,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,18,167:6:0 0,15,167:5:0 +17 1221 . A 0 . DP=20;I16=12,8,0,0,722,26564,0,0,1200,72000,0,0,390,9330,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,147:5:0 0,15,157:5:0 +17 1222 . T 0 . DP=18;I16=10,8,0,0,666,25034,0,0,1080,64800,0,0,389,9333,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,245:9:0 0,15,143:5:0 0,12,142:4:0 +17 1223 . T 0 . DP=17;I16=9,7,0,0,574,21262,0,0,960,57600,0,0,364,8720,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,232:9:0 0,12,122:4:0 0,9,120:3:0 +17 1224 . C 0 . DP=19;I16=10,7,0,0,639,24429,0,0,1020,61200,0,0,364,8740,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,128:4:0 0,9,112:3:0 +17 1225 . A 0 . DP=19;I16=10,9,0,0,713,27139,0,0,1109,65641,0,0,395,9419,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,137:5:0 0,12,145:4:0 +17 1226 . A 0 . DP=19;I16=10,9,0,0,688,25468,0,0,1109,65641,0,0,397,9469,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,127:5:0 0,12,147:4:0 +17 1227 . A 0 . DP=19;I16=10,9,0,0,698,26104,0,0,1109,65641,0,0,399,9531,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,133:5:0 0,12,146:4:0 +17 1228 . A 0 . DP=19;I16=10,9,0,0,705,26721,0,0,1109,65641,0,0,399,9505,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,143:5:0 0,12,145:4:0 +17 1229 . A 0 . DP=18;I16=10,8,0,0,693,26891,0,0,1049,62041,0,0,400,9490,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,123:4:0 0,12,138:4:0 +17 1230 . T 0 . DP=18;I16=10,8,0,0,643,23601,0,0,1049,62041,0,0,401,9485,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,30,245:10:0 0,12,115:4:0 0,12,144:4:0 +17 1231 . C 0 . DP=18;I16=10,7,0,0,663,26041,0,0,1020,61200,0,0,390,9320,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,98:3:0 0,12,138:4:0 +17 1232 . T 0 . DP=18;I16=10,8,0,0,683,26261,0,0,1049,62041,0,0,401,9409,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,133:4:0 0,12,129:4:0 +17 1233 . G 0 . DP=18;I16=10,8,0,0,657,24509,0,0,1049,62041,0,0,401,9389,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,124:4:0 0,12,129:4:0 +17 1234 . A 0 . DP=19;I16=10,8,0,0,677,26177,0,0,1080,64800,0,0,386,9134,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,101:3:0 0,12,144:4:0 +17 1235 . A 0 . DP=19;I16=10,9,0,0,697,26363,0,0,1109,65641,0,0,400,9282,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,129:4:0 0,12,140:4:0 +17 1236 . A 0 . DP=19;I16=10,9,0,0,671,24693,0,0,1109,65641,0,0,398,9148,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,103:4:0 0,12,136:4:0 +17 1237 . T 0 . DP=19;I16=9,9,0,0,649,24061,0,0,1049,62041,0,0,370,8356,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,98:3:0 0,12,135:4:0 +17 1238 . C 0 . DP=20;I16=11,9,0,0,733,27709,0,0,1169,69241,0,0,391,8783,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,104:4:0 0,12,145:4:0 +17 1239 . C 0 . DP=20;I16=10,9,0,0,672,24596,0,0,1109,65641,0,0,363,7981,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,76:3:0 0,12,124:4:0 +17 1240 . C 0 . DP=20;I16=11,9,0,0,723,26895,0,0,1169,69241,0,0,385,8451,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,118:4:0 0,12,129:4:0 +17 1241 . A 0 . DP=20;I16=11,9,0,0,719,26575,0,0,1169,69241,0,0,382,8318,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,104:4:0 0,12,141:4:0 +17 1242 . A 0 . DP=21;I16=12,9,0,0,749,27599,0,0,1229,72841,0,0,379,8207,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,109:4:0 0,15,153:5:0 +17 1243 . A 0 . DP=21;I16=12,9,0,0,738,26862,0,0,1229,72841,0,0,377,8119,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,110:4:0 0,15,158:5:0 +17 1244 . C 0 . DP=21;I16=12,8,0,0,670,22952,0,0,1169,69241,0,0,365,7955,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,101:4:0 0,15,148:5:0 +17 1245 . G 0 . DP=21;I16=12,9,0,0,657,21627,0,0,1229,72841,0,0,373,8015,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,245:12:0 0,12,95:4:0 0,15,158:5:0 +17 1246 . C 0 . DP=21;I16=12,9,0,0,652,21348,0,0,1229,72841,0,0,370,7948,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,252:12:0 0,12,95:4:0 0,15,146:5:0 +17 1247 . G 0 . DP=20;I16=11,9,0,0,655,22291,0,0,1169,69241,0,0,367,7853,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,87:4:0 0,15,150:5:0 +17 1248 . C 0 . DP=20;I16=10,8,0,0,659,25037,0,0,1080,64800,0,0,314,6530,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,90:3:0 0,15,156:5:0 +17 1249 . C 0 . DP=21;I16=12,9,0,0,772,28954,0,0,1229,72841,0,0,360,7680,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,111:4:0 0,15,166:5:0 +17 1250 . A 0 . DP=21;I16=12,9,0,0,757,27599,0,0,1229,72841,0,0,356,7554,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,114:4:0 0,15,161:5:0 +17 1251 . A 0 . DP=21;I16=12,9,0,0,758,27890,0,0,1229,72841,0,0,352,7452,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,115:4:0 0,15,174:5:0 +17 1252 . T 0 . DP=21;I16=12,9,0,0,758,27574,0,0,1229,72841,0,0,348,7374,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,124:4:0 0,15,159:5:0 +17 1253 . A 0 . DP=20;I16=12,8,0,0,718,26292,0,0,1169,69241,0,0,345,7319,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,127:4:0 0,12,144:4:0 +17 1254 . A 0 . DP=20;I16=12,8,0,0,781,30817,0,0,1169,69241,0,0,342,7286,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,134:4:0 0,12,156:4:0 +17 1255 . G 0 . DP=21;I16=12,9,0,0,785,30039,0,0,1229,72841,0,0,339,7275,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,128:4:0 0,15,169:5:0 +17 1256 . C 0 . DP=20;I16=12,8,0,0,742,27910,0,0,1169,69241,0,0,338,7286,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,116:4:0 0,15,165:5:0 +17 1257 . A 0 . DP=20;I16=12,8,0,0,745,28017,0,0,1169,69241,0,0,337,7319,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,132:4:0 0,15,167:5:0 +17 1258 . T 0 . DP=20;I16=12,8,0,0,753,28507,0,0,1169,69241,0,0,336,7374,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,126:4:0 0,15,170:5:0 +17 1259 . T 0 . DP=20;I16=12,8,0,0,690,24762,0,0,1169,69241,0,0,335,7451,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,236:11:0 0,12,128:4:0 0,15,170:5:0 +17 1260 . C 0 . DP=20;I16=12,8,0,0,719,26541,0,0,1169,69241,0,0,333,7499,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,127:4:0 0,15,155:5:0 +17 1261 . C 0 . DP=18;I16=11,6,0,0,602,22374,0,0,989,58441,0,0,308,6940,0,0;QS=3,0;MQSB=0.85832;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,117:4:0 0,9,109:3:0 +17 1262 . C 0 . DP=18;I16=12,6,0,0,653,24345,0,0,1049,62041,0,0,333,7597,0,0;QS=3,0;MQSB=0.85394;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,15,145:5:0 0,9,114:3:0 +17 1263 . T 0 . DP=17;I16=12,5,0,0,654,25656,0,0,989,58441,0,0,335,7645,0,0;QS=3,0;MQSB=0.818731;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,15,158:5:0 0,9,118:3:0 +17 1264 . T 0 . DP=17;I16=12,5,0,0,615,22855,0,0,989,58441,0,0,336,7658,0,0;QS=3,0;MQSB=0.818731;MQ0F=0 PL:DP:DV 0,27,226:9:0 0,15,149:5:0 0,9,114:3:0 +17 1265 . T 0 . DP=17;I16=12,5,0,0,620,23176,0,0,989,58441,0,0,334,7538,0,0;QS=3,0;MQSB=0.818731;MQ0F=0 PL:DP:DV 0,27,232:9:0 0,15,144:5:0 0,9,114:3:0 +17 1266 . G 0 . DP=18;I16=13,5,0,0,675,25765,0,0,1049,62041,0,0,332,7438,0,0;QS=3,0;MQSB=0.814433;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,145:5:0 0,9,114:3:0 +17 1267 . A 0 . DP=18;I16=13,5,0,0,663,24799,0,0,1049,62041,0,0,331,7359,0,0;QS=3,0;MQSB=0.814433;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,15,138:5:0 0,9,114:3:0 +17 1268 . G 0 . DP=18;I16=13,5,0,0,638,23584,0,0,1049,62041,0,0,329,7251,0,0;QS=3,0;MQSB=0.814433;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,112:5:0 0,9,108:3:0 +17 1269 . C 0 . DP=18;I16=13,5,0,0,592,20458,0,0,1049,62041,0,0,327,7163,0,0;QS=3,0;MQSB=0.814433;MQ0F=0 PL:DP:DV 0,30,224:10:0 0,15,130:5:0 0,9,107:3:0 +17 1270 . G 0 . DP=18;I16=13,5,0,0,537,16775,0,0,1049,62041,0,0,325,7095,0,0;QS=3,0;MQSB=0.814433;MQ0F=0 PL:DP:DV 0,30,206:10:0 0,15,104:5:0 0,9,98:3:0 +17 1271 . T 0 . DP=18;I16=12,5,0,0,620,22824,0,0,989,58441,0,0,298,6422,0,0;QS=3,0;MQSB=0.818731;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,15,138:5:0 0,9,109:3:0 +17 1272 . C 0 . DP=17;I16=11,5,0,0,597,22587,0,0,929,54841,0,0,297,6393,0,0;QS=3,0;MQSB=0.823561;MQ0F=0 PL:DP:DV 0,27,251:9:0 0,12,113:4:0 0,9,110:3:0 +17 1273 . A 0 . DP=18;I16=12,6,0,0,633,23063,0,0,1049,62041,0,0,318,6866,0,0;QS=3,0;MQSB=0.85394;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,109:4:0 0,9,113:3:0 +17 1274 . T 0 . DP=17;I16=10,6,0,0,609,23335,0,0,929,54841,0,0,293,6205,0,0;QS=3,0;MQSB=0.863243;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,67:2:0 0,9,115:3:0 +17 1275 . G 0 . DP=17;I16=11,6,0,0,602,21976,0,0,989,58441,0,0,317,6763,0,0;QS=3,0;MQSB=0.85832;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,87:3:0 0,9,112:3:0 +17 1276 . T 0 . DP=17;I16=11,6,0,0,587,20925,0,0,989,58441,0,0,316,6714,0,0;QS=3,0;MQSB=0.85832;MQ0F=0 PL:DP:DV 0,33,248:11:0 0,9,94:3:0 0,9,110:3:0 +17 1277 . C 0 . DP=18;I16=11,7,0,0,590,20126,0,0,1049,62041,0,0,314,6634,0,0;QS=3,0;MQSB=0.883327;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,85:3:0 0,9,106:3:0 +17 1278 . G 0 . DP=18;I16=11,7,0,0,603,20675,0,0,1049,62041,0,0,313,6575,0,0;QS=3,0;MQSB=0.883327;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,77:3:0 0,9,96:3:0 +17 1279 . G 0 . DP=18;I16=11,7,0,0,646,23662,0,0,1049,62041,0,0,312,6538,0,0;QS=3,0;MQSB=0.883327;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,85:3:0 0,9,113:3:0 +17 1280 . T 0 . DP=18;I16=10,7,0,0,558,19192,0,0,989,58441,0,0,296,6298,0,0;QS=3,0;MQSB=0.887766;MQ0F=0 PL:DP:DV 0,33,249:11:0 0,9,86:3:0 0,9,97:3:0 +17 1281 . G 0 . DP=17;I16=10,6,0,0,564,21244,0,0,929,54841,0,0,270,5658,0,0;QS=3,0;MQSB=0.863243;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,85:3:0 0,9,103:3:0 +17 1282 . C 0 . DP=18;I16=10,8,0,0,654,24308,0,0,1049,62041,0,0,294,6286,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,94:3:0 0,12,131:4:0 +17 1283 . T 0 . DP=18;I16=10,8,0,0,677,26313,0,0,1049,62041,0,0,294,6308,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,83:3:0 0,12,154:4:0 +17 1284 . T 0 . DP=18;I16=10,8,0,0,631,22949,0,0,1049,62041,0,0,293,6301,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,9,92:3:0 0,12,145:4:0 +17 1285 . G 0 . DP=18;I16=10,7,0,0,657,25545,0,0,989,58441,0,0,267,5691,0,0;QS=3,0;MQSB=0.887766;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,94:3:0 0,12,145:4:0 +17 1286 . G 0 . DP=18;I16=10,8,0,0,650,24684,0,0,1049,62041,0,0,291,6353,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,78:3:0 0,12,148:4:0 +17 1287 . A 0 . DP=17;I16=9,8,0,0,609,22229,0,0,989,58441,0,0,291,6411,0,0;QS=3,0;MQSB=0.91051;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,91:3:0 0,12,137:4:0 +17 1288 . A 0 . DP=17;I16=9,8,0,0,605,22315,0,0,989,58441,0,0,290,6438,0,0;QS=3,0;MQSB=0.91051;MQ0F=0 PL:DP:DV 0,30,245:10:0 0,9,103:3:0 0,12,140:4:0 +17 1289 . T 0 . DP=18;I16=10,8,0,0,637,23207,0,0,1049,62041,0,0,289,6483,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,99:3:0 0,12,141:4:0 +17 1290 . G 0 . DP=15;I16=9,6,0,0,559,21163,0,0,869,51241,0,0,292,6544,0,0;QS=3,0;MQSB=0.868815;MQ0F=0 PL:DP:DV 0,27,242:9:0 0,9,97:3:0 0,9,106:3:0 +17 1291 . T 0 . DP=15;I16=9,6,0,0,547,20303,0,0,869,51241,0,0,295,6619,0,0;QS=3,0;MQSB=0.868815;MQ0F=0 PL:DP:DV 0,27,225:9:0 0,9,91:3:0 0,9,117:3:0 +17 1292 . T 0 . DP=15;I16=9,6,0,0,559,21121,0,0,869,51241,0,0,297,6657,0,0;QS=3,0;MQSB=0.868815;MQ0F=0 PL:DP:DV 0,27,236:9:0 0,9,95:3:0 0,9,113:3:0 +17 1293 . T 0 . DP=15;I16=9,6,0,0,578,22428,0,0,869,51241,0,0,299,6707,0,0;QS=3,0;MQSB=0.868815;MQ0F=0 PL:DP:DV 0,27,242:9:0 0,9,100:3:0 0,9,116:3:0 +17 1294 . G 0 . DP=16;I16=9,7,0,0,606,23572,0,0,929,54841,0,0,301,6769,0,0;QS=3,0;MQSB=0.892753;MQ0F=0 PL:DP:DV 0,27,254:9:0 0,12,110:4:0 0,9,119:3:0 +17 1295 . G 0 . DP=16;I16=9,7,0,0,567,21419,0,0,929,54841,0,0,304,6844,0,0;QS=3,0;MQSB=0.892753;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,12,102:4:0 0,9,114:3:0 +17 1296 . G 0 . DP=16;I16=8,7,0,0,518,19300,0,0,869,51241,0,0,294,6740,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,9,89:3:0 0,9,114:3:0 +17 1297 . G 0 . DP=18;I16=9,8,0,0,551,19323,0,0,958,55682,0,0,322,7444,0,0;QS=3,0;MQSB=0.998843;MQ0F=0 PL:DP:DV 0,30,219:10:0 0,9,86:3:0 0,12,133:4:0 +17 1298 . T 0 . DP=18;I16=10,8,0,0,615,22371,0,0,1018,59282,0,0,336,7638,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,30,233:10:0 0,12,105:4:0 0,12,138:4:0 +17 1299 . T 0 . DP=18;I16=9,8,0,0,619,23135,0,0,958,55682,0,0,328,7548,0,0;QS=3,0;MQSB=0.998843;MQ0F=0 PL:DP:DV 0,30,242:10:0 0,9,97:3:0 0,12,136:4:0 +17 1300 . T 0 . DP=18;I16=10,8,0,0,631,23107,0,0,1018,59282,0,0,338,7638,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,30,235:10:0 0,12,121:4:0 0,12,136:4:0 +17 1301 . T G, 0 . DP=18;I16=8,8,1,0,599,22623,18,324,929,54841,29,841,314,7040,25,625;QS=2.9434,0.0566038,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.998843;BQB=1;MQ0F=0 PL:DP:DV 0,9,213,24,216,222:9:1 0,12,126,12,126,126:4:0 0,12,135,12,135,135:4:0 +17 1302 . G 0 . DP=17;I16=9,8,0,0,624,23544,0,0,958,55682,0,0,341,7709,0,0;QS=3,0;MQSB=0.998843;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,12,127:4:0 0,12,140:4:0 +17 1303 . G 0 . DP=17;I16=9,8,0,0,582,21200,0,0,958,55682,0,0,342,7718,0,0;QS=3,0;MQSB=0.998843;MQ0F=0 PL:DP:DV 0,27,217:9:0 0,12,125:4:0 0,12,138:4:0 +17 1304 . A 0 . DP=18;I16=10,8,0,0,652,24124,0,0,1018,59282,0,0,343,7741,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,27,218:9:0 0,12,131:4:0 0,15,169:5:0 +17 1305 . T 0 . DP=18;I16=10,8,0,0,685,26381,0,0,1018,59282,0,0,345,7779,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,12,122:4:0 0,15,174:5:0 +17 1306 . T 0 . DP=18;I16=9,8,0,0,644,24628,0,0,958,55682,0,0,345,7829,0,0;QS=3,0;MQSB=0.998843;MQ0F=0 PL:DP:DV 0,27,236:9:0 0,9,106:3:0 0,15,168:5:0 +17 1307 . T 0 . DP=17;I16=9,8,0,0,628,23746,0,0,958,55682,0,0,348,7902,0,0;QS=3,0;MQSB=0.998843;MQ0F=0 PL:DP:DV 0,27,226:9:0 0,9,104:3:0 0,15,167:5:0 +17 1308 . A 0 . DP=19;I16=9,10,0,0,690,25500,0,0,1078,62882,0,0,350,7938,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,30,236:10:0 0,12,127:4:0 0,15,173:5:0 +17 1309 . C 0 . DP=19;I16=9,9,0,0,698,27148,0,0,1049,62041,0,0,342,7818,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,106:3:0 0,15,169:5:0 +17 1310 . A 0 . DP=19;I16=9,10,0,0,751,29953,0,0,1078,62882,0,0,356,7958,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,132:4:0 0,15,183:5:0 +17 1311 . G 0 . DP=19;I16=9,10,0,0,742,29384,0,0,1078,62882,0,0,359,7995,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,128:4:0 0,15,174:5:0 +17 1312 . C 0 . DP=19;I16=9,10,0,0,717,27783,0,0,1078,62882,0,0,362,8050,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,115:4:0 0,15,166:5:0 +17 1313 . T 0 . DP=19;I16=9,10,0,0,751,30061,0,0,1078,62882,0,0,364,8074,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,135:4:0 0,15,175:5:0 +17 1314 . T 0 . DP=19;I16=9,10,0,0,707,26983,0,0,1078,62882,0,0,366,8118,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,30,245:10:0 0,12,134:4:0 0,15,174:5:0 +17 1315 . T 0 . DP=19;I16=9,10,0,0,717,27491,0,0,1078,62882,0,0,367,8131,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,12,132:4:0 0,15,174:5:0 +17 1316 . G 0 . DP=21;I16=10,11,0,0,776,29502,0,0,1198,70082,0,0,368,8162,0,0;QS=3,0;MQSB=0.99938;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,128:4:0 0,18,188:6:0 +17 1317 . G 0 . DP=21;I16=10,11,0,0,751,27855,0,0,1198,70082,0,0,371,8213,0,0;QS=3,0;MQSB=0.99938;MQ0F=0 PL:DP:DV 0,33,253:11:0 0,12,130:4:0 0,18,179:6:0 +17 1318 . G 0 . DP=21;I16=10,11,0,0,749,27663,0,0,1198,70082,0,0,372,8188,0,0;QS=3,0;MQSB=0.99938;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,130:4:0 0,18,184:6:0 +17 1319 . A 0 . DP=21;I16=10,11,0,0,768,28390,0,0,1198,70082,0,0,373,8189,0,0;QS=3,0;MQSB=0.99938;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,124:4:0 0,18,186:6:0 +17 1320 . C 0 . DP=21;I16=10,11,0,0,728,25496,0,0,1198,70082,0,0,373,8165,0,0;QS=3,0;MQSB=0.99938;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,113:4:0 0,18,161:6:0 +17 1321 . G 0 . DP=22;I16=10,12,0,0,762,27412,0,0,1289,76441,0,0,374,8164,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,33,244:11:0 0,9,104:3:0 0,24,208:8:0 +17 1322 . C 0 . DP=22;I16=10,12,0,0,852,33528,0,0,1289,76441,0,0,377,8187,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,111:3:0 0,24,225:8:0 +17 1323 . T 0 . DP=22;I16=10,12,0,0,874,35152,0,0,1289,76441,0,0,379,8185,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,112:3:0 0,24,237:8:0 +17 1324 . C 0 . DP=21;I16=9,12,0,0,793,30585,0,0,1229,72841,0,0,381,8157,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,109:3:0 0,24,218:8:0 +17 1325 . A 0 . DP=21;I16=9,12,0,0,782,29430,0,0,1229,72841,0,0,383,8153,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,105:3:0 0,24,218:8:0 +17 1326 . A 0 . DP=21;I16=9,12,0,0,791,30479,0,0,1229,72841,0,0,385,8173,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,9,108:3:0 0,24,230:8:0 +17 1327 . C 0 . DP=23;I16=11,12,0,0,834,31048,0,0,1349,80041,0,0,387,8217,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,99:3:0 0,27,237:9:0 +17 1328 . C 0 . DP=23;I16=11,12,0,0,878,33972,0,0,1349,80041,0,0,391,8287,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,105:3:0 0,27,254:9:0 +17 1329 . T 0 . DP=23;I16=11,12,0,0,882,34756,0,0,1349,80041,0,0,395,8385,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,112:3:0 0,27,255:9:0 +17 1330 . G 0 . DP=23;I16=11,12,0,0,856,32638,0,0,1349,80041,0,0,398,8460,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,101:3:0 0,27,241:9:0 +17 1331 . T 0 . DP=23;I16=11,12,0,0,847,31785,0,0,1349,80041,0,0,400,8512,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,106:3:0 0,27,247:9:0 +17 1332 . A 0 . DP=23;I16=11,12,0,0,826,30264,0,0,1349,80041,0,0,402,8592,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,252:11:0 0,9,104:3:0 0,27,238:9:0 +17 1333 . C 0 . DP=23;I16=11,12,0,0,836,30928,0,0,1349,80041,0,0,404,8700,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,101:3:0 0,27,236:9:0 +17 1334 . C 0 . DP=22;I16=11,11,0,0,830,32380,0,0,1289,76441,0,0,405,8733,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,107:3:0 0,27,238:9:0 +17 1335 . T 0 . DP=22;I16=11,11,0,0,877,35371,0,0,1289,76441,0,0,406,8788,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,113:3:0 0,27,253:9:0 +17 1336 . C 0 . DP=25;I16=12,12,0,0,890,33648,0,0,1378,80882,0,0,398,8784,0,0;QS=3,0;MQSB=0.786628;MQ0F=0 PL:DP:DV 0,33,250:11:0 0,12,131:4:0 0,27,237:9:0 +17 1337 . A 0 . DP=26;I16=13,13,0,0,941,34611,0,0,1498,88082,0,0,411,8967,0,0;QS=3,0;MQSB=0.800737;MQ0F=0 PL:DP:DV 0,33,249:11:0 0,15,152:5:0 0,30,247:10:0 +17 1338 . A 0 . DP=26;I16=12,14,0,0,982,37358,0,0,1498,88082,0,0,416,9048,0,0;QS=3,0;MQSB=0.771623;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,153:5:0 0,30,255:10:0 +17 1339 . T 0 . DP=27;I16=12,15,0,0,989,36855,0,0,1558,91682,0,0,422,9160,0,0;QS=3,0;MQSB=0.765017;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,151:5:0 0,33,255:11:0 +17 1340 . A 0 . DP=27;I16=11,15,0,0,937,34141,0,0,1498,88082,0,0,425,9289,0,0;QS=3,0;MQSB=0.738577;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,15,149:5:0 0,33,254:11:0 +17 1341 . A 0 . DP=27;I16=12,14,0,0,929,33961,0,0,1498,88082,0,0,410,8810,0,0;QS=3,0;MQSB=0.771623;MQ0F=0 PL:DP:DV 0,30,245:10:0 0,15,141:5:0 0,33,255:11:0 +17 1342 . A 0 . DP=27;I16=12,15,0,0,951,34575,0,0,1558,91682,0,0,439,9499,0,0;QS=3,0;MQSB=0.765017;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,15,159:5:0 0,33,249:11:0 +17 1343 . C 0 . DP=25;I16=10,15,0,0,902,33364,0,0,1469,87241,0,0,445,9593,0,0;QS=3,0;MQSB=0.9171;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,140:5:0 0,30,233:10:0 +17 1344 . C 0 . DP=26;I16=10,16,0,0,985,37915,0,0,1529,90841,0,0,451,9715,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,163:6:0 0,30,238:10:0 +17 1345 . T 0 . DP=26;I16=10,16,0,0,1004,39262,0,0,1529,90841,0,0,458,9866,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,182:6:0 0,30,242:10:0 +17 1346 . G 0 . DP=26;I16=10,16,0,0,1003,38983,0,0,1529,90841,0,0,465,10047,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,172:6:0 0,30,239:10:0 +17 1347 . A 0 . DP=26;I16=10,16,0,0,995,38409,0,0,1529,90841,0,0,470,10156,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,177:6:0 0,30,243:10:0 +17 1348 . T 0 . DP=26;I16=10,16,0,0,988,38126,0,0,1529,90841,0,0,474,10242,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,18,185:6:0 0,30,251:10:0 +17 1349 . T 0 . DP=26;I16=9,15,0,0,905,34409,0,0,1409,83641,0,0,454,9730,0,0;QS=3,0;MQSB=0.904837;MQ0F=0 PL:DP:DV 0,24,225:8:0 0,18,176:6:0 0,30,248:10:0 +17 1350 . T 0 . DP=26;I16=10,16,0,0,975,36909,0,0,1498,88082,0,0,485,10495,0,0;QS=3,0;MQSB=0.700784;MQ0F=0 PL:DP:DV 0,27,242:9:0 0,21,195:7:0 0,30,249:10:0 +17 1351 . T 0 . DP=26;I16=10,16,0,0,956,35602,0,0,1498,88082,0,0,491,10663,0,0;QS=3,0;MQSB=0.700784;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,21,193:7:0 0,30,240:10:0 +17 1352 . A 0 . DP=26;I16=10,16,0,0,901,31965,0,0,1498,88082,0,0,496,10810,0,0;QS=3,0;MQSB=0.700784;MQ0F=0 PL:DP:DV 0,27,250:9:0 0,21,180:7:0 0,30,211:10:0 +17 1353 . A 0 . DP=26;I16=10,16,0,0,927,33583,0,0,1498,88082,0,0,499,10885,0,0;QS=3,0;MQSB=0.700784;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,21,187:7:0 0,30,224:10:0 +17 1354 . A 0 . DP=26;I16=10,16,0,0,927,33621,0,0,1498,88082,0,0,502,10986,0,0;QS=3,0;MQSB=0.700784;MQ0F=0 PL:DP:DV 0,27,237:9:0 0,21,190:7:0 0,30,223:10:0 +17 1355 . A 0 . DP=26;I16=10,16,0,0,924,33736,0,0,1498,88082,0,0,505,11113,0,0;QS=3,0;MQSB=0.700784;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,21,186:7:0 0,30,227:10:0 +17 1356 . A 0 . DP=25;I16=10,15,0,0,916,34050,0,0,1438,84482,0,0,509,11265,0,0;QS=3,0;MQSB=0.707404;MQ0F=0 PL:DP:DV 0,27,249:9:0 0,21,178:7:0 0,27,226:9:0 +17 1357 . A 0 . DP=25;I16=9,15,0,0,949,38007,0,0,1378,80882,0,0,488,10816,0,0;QS=3,0;MQSB=0.67032;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,21,193:7:0 0,24,217:8:0 +17 1358 . G 0 . DP=25;I16=9,15,0,0,873,32435,0,0,1378,80882,0,0,491,10967,0,0;QS=3,0;MQSB=0.67032;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,21,172:7:0 0,24,188:8:0 +17 1359 . T 0 . DP=25;I16=9,15,0,0,857,31139,0,0,1378,80882,0,0,494,11144,0,0;QS=3,0;MQSB=0.67032;MQ0F=0 PL:DP:DV 0,27,232:9:0 0,21,184:7:0 0,24,196:8:0 +17 1360 . T 0 . DP=25;I16=9,15,0,0,879,32419,0,0,1378,80882,0,0,497,11347,0,0;QS=3,0;MQSB=0.67032;MQ0F=0 PL:DP:DV 0,27,248:9:0 0,21,184:7:0 0,24,192:8:0 +17 1361 . T 0 . DP=27;I16=9,17,0,0,936,34238,0,0,1498,88082,0,0,500,11576,0,0;QS=3,0;MQSB=0.657209;MQ0F=0 PL:DP:DV 0,27,234:9:0 0,24,201:8:0 0,27,206:9:0 +17 1362 . G 0 . DP=26;I16=9,17,0,0,973,36785,0,0,1498,88082,0,0,502,11680,0,0;QS=3,0;MQSB=0.657209;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,24,202:8:0 0,27,207:9:0 +17 1363 . G 0 . DP=25;I16=8,17,0,0,936,35390,0,0,1438,84482,0,0,504,11756,0,0;QS=3,0;MQSB=0.612391;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,21,181:7:0 0,27,202:9:0 +17 1364 . G 0 . DP=25;I16=8,17,0,0,902,32840,0,0,1438,84482,0,0,504,11752,0,0;QS=3,0;MQSB=0.612391;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,21,184:7:0 0,27,200:9:0 +17 1365 . G 0 . DP=26;I16=9,17,0,0,946,35224,0,0,1498,88082,0,0,503,11717,0,0;QS=3,0;MQSB=0.657209;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,24,190:8:0 0,27,202:9:0 +17 1366 . G 0 . DP=25;I16=8,15,0,0,840,31058,0,0,1318,77282,0,0,454,10450,0,0;QS=3,0;MQSB=0.625784;MQ0F=0 PL:DP:DV 0,21,215:7:0 0,21,181:7:0 0,27,199:9:0 +17 1367 . G C, 0 . DP=25;I16=7,16,0,1,836,30888,27,729,1349,80041,60,3600,472,11152,15,225;QS=2.91641,0.0835913,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.864405;BQB=1;MQ0F=0 PL:DP:DV 0,24,236,24,236,236:8:0 0,21,179,21,179,179:7:0 0,0,171,24,174,189:9:1 +17 1368 . A 0 . DP=26;I16=8,17,0,0,869,30839,0,0,1438,84482,0,0,481,11095,0,0;QS=3,0;MQSB=0.612391;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,21,180:7:0 0,27,197:9:0 +17 1369 . T 0 . DP=26;I16=8,18,0,0,902,32160,0,0,1498,88082,0,0,508,11758,0,0;QS=3,0;MQSB=0.606531;MQ0F=0 PL:DP:DV 0,27,242:9:0 0,24,197:8:0 0,27,194:9:0 +17 1370 . T 0 . DP=27;I16=8,17,0,0,926,34736,0,0,1438,84482,0,0,458,10466,0,0;QS=3,0;MQSB=0.612391;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,21,195:7:0 0,27,215:9:0 +17 1371 . C 0 . DP=27;I16=8,19,0,0,929,33255,0,0,1558,91682,0,0,509,11695,0,0;QS=3,0;MQSB=0.601139;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,24,196:8:0 0,30,196:10:0 +17 1372 . C 0 . DP=27;I16=8,19,0,0,954,34882,0,0,1558,91682,0,0,510,11696,0,0;QS=3,0;MQSB=0.601139;MQ0F=0 PL:DP:DV 0,27,251:9:0 0,24,198:8:0 0,30,200:10:0 +17 1373 . C 0 . DP=26;I16=8,17,0,0,892,32692,0,0,1438,84482,0,0,486,11044,0,0;QS=3,0;MQSB=0.612391;MQ0F=0 PL:DP:DV 0,24,243:8:0 0,21,186:7:0 0,30,195:10:0 +17 1374 . C 0 . DP=26;I16=8,17,0,0,953,36553,0,0,1438,84482,0,0,487,11039,0,0;QS=3,0;MQSB=0.612391;MQ0F=0 PL:DP:DV 0,24,249:8:0 0,21,193:7:0 0,30,211:10:0 +17 1375 . T 0 . DP=27;I16=9,18,0,0,1011,38377,0,0,1558,91682,0,0,512,11630,0,0;QS=3,0;MQSB=0.651439;MQ0F=0 PL:DP:DV 0,27,243:9:0 0,24,215:8:0 0,30,215:10:0 +17 1376 . A 0 . DP=27;I16=9,17,0,0,912,32444,0,0,1498,88082,0,0,488,10992,0,0;QS=3,0;MQSB=0.657209;MQ0F=0 PL:DP:DV 0,27,234:9:0 0,21,198:7:0 0,30,195:10:0 +17 1377 . A 0 . DP=26;I16=9,17,0,0,994,38518,0,0,1498,88082,0,0,515,11625,0,0;QS=3,0;MQSB=0.657209;MQ0F=0 PL:DP:DV 0,24,228:8:0 0,24,221:8:0 0,30,228:10:0 +17 1378 . G 0 . DP=26;I16=9,17,0,0,910,33180,0,0,1498,88082,0,0,517,11653,0,0;QS=3,0;MQSB=0.657209;MQ0F=0 PL:DP:DV 0,24,234:8:0 0,24,199:8:0 0,30,197:10:0 +17 1379 . C 0 . DP=26;I16=9,17,0,0,891,31779,0,0,1498,88082,0,0,519,11701,0,0;QS=3,0;MQSB=0.657209;MQ0F=0 PL:DP:DV 0,24,228:8:0 0,24,198:8:0 0,30,193:10:0 +17 1380 . C 0 . DP=26;I16=9,17,0,0,925,33925,0,0,1498,88082,0,0,520,11720,0,0;QS=3,0;MQSB=0.657209;MQ0F=0 PL:DP:DV 0,24,226:8:0 0,24,202:8:0 0,30,209:10:0 +17 1381 . C 0 . DP=28;I16=10,18,0,0,878,28560,0,0,1618,95282,0,0,521,11761,0,0;QS=3,0;MQSB=0.689069;MQ0F=0 PL:DP:DV 0,24,211:8:0 0,24,177:8:0 0,36,208:12:0 +17 1382 . G 0 . DP=28;I16=8,18,0,0,905,32553,0,0,1529,90841,0,0,482,10912,0,0;QS=3,0;MQSB=0.882497;MQ0F=0 PL:DP:DV 0,24,213:8:0 0,18,152:6:0 0,36,243:12:0 +17 1383 . C 0 . DP=27;I16=10,16,0,0,897,32373,0,0,1498,88082,0,0,502,11242,0,0;QS=3,0;MQSB=0.700784;MQ0F=0 PL:DP:DV 0,24,225:8:0 0,21,163:7:0 0,33,241:11:0 +17 1384 . C 0 . DP=28;I16=11,17,0,0,980,35558,0,0,1618,95282,0,0,529,11885,0,0;QS=3,0;MQSB=0.726331;MQ0F=0 PL:DP:DV 0,27,248:9:0 0,24,184:8:0 0,33,239:11:0 +17 1385 . A 0 . DP=30;I16=11,18,0,0,949,33215,0,0,1678,98882,0,0,508,11356,0,0;QS=3,0;MQSB=0.720887;MQ0F=0 PL:DP:DV 0,30,232:10:0 0,27,185:9:0 0,30,234:10:0 +17 1386 . C 0 . DP=30;I16=11,19,0,0,1088,39938,0,0,1738,102482,0,0,537,12011,0,0;QS=3,0;MQSB=0.715831;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,27,218:9:0 0,33,255:11:0 +17 1387 . C 0 . DP=31;I16=12,19,0,0,1101,40297,0,0,1798,106082,0,0,540,12022,0,0;QS=3,0;MQSB=0.743137;MQ0F=0 PL:DP:DV 0,33,250:11:0 0,27,219:9:0 0,33,252:11:0 +17 1388 . C 0 . DP=31;I16=11,19,0,0,999,34081,0,0,1769,105241,0,0,519,11439,0,0;QS=3,0;MQSB=0.91982;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,185:8:0 0,33,211:11:0 +17 1389 . G 0 . DP=31;I16=11,19,0,0,1065,39119,0,0,1738,102482,0,0,535,11941,0,0;QS=3,0;MQSB=0.715831;MQ0F=0 PL:DP:DV 0,27,234:9:0 0,30,234:10:0 0,33,255:11:0 +17 1390 . G 0 . DP=31;I16=12,19,0,0,1152,43744,0,0,1798,106082,0,0,555,12241,0,0;QS=3,0;MQSB=0.743137;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,30,245:10:0 0,33,255:11:0 +17 1391 . A 0 . DP=31;I16=12,19,0,0,1241,50255,0,0,1798,106082,0,0,560,12326,0,0;QS=3,0;MQSB=0.743137;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,30,255:10:0 0,33,255:11:0 +17 1392 . G 0 . DP=31;I16=12,19,0,0,1160,44364,0,0,1798,106082,0,0,564,12392,0,0;QS=3,0;MQSB=0.743137;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,30,250:10:0 0,33,255:11:0 +17 1393 . A 0 . DP=31;I16=12,19,0,0,1123,41811,0,0,1798,106082,0,0,568,12490,0,0;QS=3,0;MQSB=0.743137;MQ0F=0 PL:DP:DV 0,30,228:10:0 0,30,255:10:0 0,33,255:11:0 +17 1394 . C 0 . DP=31;I16=12,19,0,0,1139,42555,0,0,1798,106082,0,0,571,12569,0,0;QS=3,0;MQSB=0.743137;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,30,244:10:0 0,33,255:11:0 +17 1395 . A 0 . DP=31;I16=12,19,0,0,1206,48048,0,0,1798,106082,0,0,575,12677,0,0;QS=3,0;MQSB=0.743137;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,240:9:0 0,33,255:11:0 +17 1396 . G 0 . DP=31;I16=12,19,0,0,1196,46882,0,0,1798,106082,0,0,579,12763,0,0;QS=3,0;MQSB=0.743137;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,249:9:0 0,33,255:11:0 +17 1397 . C 0 . DP=31;I16=12,18,0,0,993,33339,0,0,1738,102482,0,0,579,12775,0,0;QS=3,0;MQSB=0.748022;MQ0F=0 PL:DP:DV 0,30,231:10:0 0,27,205:9:0 0,33,217:11:0 +17 1398 . G 0 . DP=30;I16=12,18,0,0,1055,38309,0,0,1738,102482,0,0,584,12826,0,0;QS=3,0;MQSB=0.748022;MQ0F=0 PL:DP:DV 0,33,250:11:0 0,27,229:9:0 0,30,244:10:0 +17 1399 . G 0 . DP=30;I16=12,18,0,0,1132,43666,0,0,1738,102482,0,0,586,12854,0,0;QS=3,0;MQSB=0.748022;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,239:9:0 0,30,255:10:0 +17 1400 . A 0 . DP=30;I16=11,18,0,0,1101,42271,0,0,1678,98882,0,0,563,12289,0,0;QS=3,0;MQSB=0.720887;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,27,239:9:0 0,30,246:10:0 +17 1401 . T 0 . DP=30;I16=12,18,0,0,1130,44170,0,0,1738,102482,0,0,589,12955,0,0;QS=3,0;MQSB=0.748022;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,251:9:0 0,30,255:10:0 +17 1402 . T 0 . DP=31;I16=13,18,0,0,1152,44058,0,0,1798,106082,0,0,589,12977,0,0;QS=3,0;MQSB=0.771348;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,244:9:0 0,30,255:10:0 +17 1403 . T 0 . DP=31;I16=13,18,0,0,1178,45296,0,0,1798,106082,0,0,590,13032,0,0;QS=3,0;MQSB=0.771348;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,249:9:0 0,30,255:10:0 +17 1404 . C 0 . DP=31;I16=13,18,0,0,1102,40838,0,0,1798,106082,0,0,591,13121,0,0;QS=3,0;MQSB=0.771348;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,236:9:0 0,30,244:10:0 +17 1405 . C 0 . DP=30;I16=12,18,0,0,1154,45216,0,0,1738,102482,0,0,593,13243,0,0;QS=3,0;MQSB=0.748022;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,241:9:0 0,27,229:9:0 +17 1406 . T 0 . DP=30;I16=12,18,0,0,1153,44919,0,0,1738,102482,0,0,595,13397,0,0;QS=3,0;MQSB=0.748022;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,248:9:0 0,27,223:9:0 +17 1407 . T 0 . DP=30;I16=11,18,0,0,1074,40182,0,0,1678,98882,0,0,570,12856,0,0;QS=3,0;MQSB=0.720887;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,231:9:0 0,27,215:9:0 +17 1408 . A 0 . DP=30;I16=12,18,0,0,1131,43363,0,0,1738,102482,0,0,596,13592,0,0;QS=3,0;MQSB=0.748022;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,30,244:10:0 0,27,234:9:0 +17 1409 . G 0 . DP=29;I16=12,17,0,0,1082,40752,0,0,1678,98882,0,0,599,13729,0,0;QS=3,0;MQSB=0.753269;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,237:9:0 0,27,204:9:0 +17 1410 . T 0 . DP=29;I16=12,17,0,0,1084,41030,0,0,1678,98882,0,0,601,13841,0,0;QS=3,0;MQSB=0.753269;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,239:9:0 0,27,218:9:0 +17 1411 . T 0 . DP=29;I16=12,17,0,0,958,32550,0,0,1678,98882,0,0,600,13826,0,0;QS=3,0;MQSB=0.753269;MQ0F=0 PL:DP:DV 0,33,250:11:0 0,27,206:9:0 0,27,194:9:0 +17 1412 . A T, 0 . DP=29;I16=11,17,1,0,924,31586,25,625,1649,98041,29,841,573,13159,24,576;QS=2.90842,0.0915751,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.753269;BQB=1;MQ0F=0 PL:DP:DV 0,33,245,33,245,245:11:0 0,2,171,24,174,187:9:1 0,27,192,27,192,192:9:0 +17 1413 . C 0 . DP=29;I16=12,17,0,0,1067,39941,0,0,1678,98882,0,0,591,13521,0,0;QS=3,0;MQSB=0.753269;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,230:9:0 0,27,209:9:0 +17 1414 . T 0 . DP=29;I16=12,17,0,0,1123,44271,0,0,1678,98882,0,0,585,13335,0,0;QS=3,0;MQSB=0.753269;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,236:9:0 0,27,221:9:0 +17 1415 . T 0 . DP=29;I16=12,17,0,0,1000,35254,0,0,1678,98882,0,0,577,13077,0,0;QS=3,0;MQSB=0.753269;MQ0F=0 PL:DP:DV 0,33,246:11:0 0,27,216:9:0 0,27,208:9:0 +17 1416 . A 0 . DP=30;I16=13,17,0,0,1026,36124,0,0,1738,102482,0,0,569,12847,0,0;QS=3,0;MQSB=0.776389;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,208:9:0 0,27,199:9:0 +17 1417 . C 0 . DP=29;I16=13,16,0,0,1111,42941,0,0,1678,98882,0,0,563,12645,0,0;QS=3,0;MQSB=0.781802;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,235:9:0 0,24,211:8:0 +17 1418 . T 0 . DP=29;I16=13,16,0,0,1111,43021,0,0,1678,98882,0,0,557,12471,0,0;QS=3,0;MQSB=0.781802;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,231:9:0 0,24,207:8:0 +17 1419 . A 0 . DP=29;I16=13,16,0,0,1039,38191,0,0,1678,98882,0,0,551,12325,0,0;QS=3,0;MQSB=0.781802;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,222:9:0 0,24,199:8:0 +17 1420 . T 0 . DP=29;I16=13,16,0,0,1039,37885,0,0,1678,98882,0,0,544,12158,0,0;QS=3,0;MQSB=0.781802;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,234:9:0 0,24,185:8:0 +17 1421 . G 0 . DP=31;I16=13,18,0,0,1129,41649,0,0,1798,106082,0,0,536,11970,0,0;QS=3,0;MQSB=0.771348;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,30,247:10:0 0,24,191:8:0 +17 1422 . C 0 . DP=29;I16=13,16,0,0,1075,40645,0,0,1678,98882,0,0,532,11810,0,0;QS=3,0;MQSB=0.781802;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,30,239:10:0 0,18,180:6:0 +17 1423 . T 0 . DP=31;I16=14,17,0,0,1179,45767,0,0,1798,106082,0,0,528,11678,0,0;QS=3,0;MQSB=0.79638;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,36,255:12:0 0,18,183:6:0 +17 1424 . C 0 . DP=30;I16=13,17,0,0,1086,40448,0,0,1738,102482,0,0,527,11575,0,0;QS=3,0;MQSB=0.776389;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,36,255:12:0 0,18,174:6:0 +17 1425 . C 0 . DP=30;I16=13,17,0,0,1124,42974,0,0,1738,102482,0,0,525,11453,0,0;QS=3,0;MQSB=0.776389;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,36,255:12:0 0,18,180:6:0 +17 1426 . T 0 . DP=32;I16=15,17,0,0,1218,47130,0,0,1858,109682,0,0,523,11363,0,0;QS=3,0;MQSB=0.813784;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,36,255:12:0 0,18,188:6:0 +17 1427 . T 0 . DP=32;I16=14,18,0,0,1126,40772,0,0,1827,106923,0,0,524,11306,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,36,255:12:0 0,18,176:6:0 +17 1428 . G 0 . DP=33;I16=15,18,0,0,1188,43596,0,0,1887,110523,0,0,525,11233,0,0;QS=3,0;MQSB=0.930476;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,36,255:12:0 0,18,166:6:0 +17 1429 . G 0 . DP=33;I16=14,18,0,0,1070,37720,0,0,1858,109682,0,0,507,10795,0,0;QS=3,0;MQSB=0.997118;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,33,243:11:0 0,18,148:6:0 +17 1430 . C 0 . DP=33;I16=15,18,0,0,1145,40795,0,0,1887,110523,0,0,529,11193,0,0;QS=3,0;MQSB=0.930476;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,36,247:12:0 0,18,157:6:0 +17 1431 . C 0 . DP=33;I16=15,18,0,0,1160,41686,0,0,1887,110523,0,0,531,11227,0,0;QS=3,0;MQSB=0.930476;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,36,253:12:0 0,18,167:6:0 +17 1432 . A 0 . DP=33;I16=15,18,0,0,1118,39032,0,0,1887,110523,0,0,533,11297,0,0;QS=3,0;MQSB=0.930476;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,36,255:12:0 0,18,169:6:0 +17 1433 . T 0 . DP=34;I16=15,19,0,0,1238,45602,0,0,1947,114123,0,0,535,11403,0,0;QS=3,0;MQSB=0.923533;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,36,255:12:0 0,18,174:6:0 +17 1434 . T 0 . DP=35;I16=15,20,0,0,1269,46757,0,0,2007,117723,0,0,537,11495,0,0;QS=3,0;MQSB=0.916855;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,36,255:12:0 0,18,179:6:0 +17 1435 . T 0 . DP=35;I16=14,20,0,0,1256,46868,0,0,1947,114123,0,0,515,10999,0,0;QS=3,0;MQSB=0.901704;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,36,255:12:0 0,18,180:6:0 +17 1436 . C 0 . DP=34;I16=14,20,0,0,1250,46978,0,0,1947,114123,0,0,544,11790,0,0;QS=3,0;MQSB=0.901704;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,36,255:12:0 0,18,165:6:0 +17 1437 . T 0 . DP=32;I16=13,19,0,0,1222,47206,0,0,1858,109682,0,0,548,11892,0,0;QS=3,0;MQSB=0.993397;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,33,255:11:0 0,15,161:5:0 +17 1438 . C 0 . DP=30;I16=13,17,0,0,1132,43284,0,0,1738,102482,0,0,554,12028,0,0;QS=3,0;MQSB=0.996503;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,30,251:10:0 0,15,159:5:0 +17 1439 . T 0 . DP=30;I16=13,17,0,0,1110,41602,0,0,1738,102482,0,0,560,12196,0,0;QS=3,0;MQSB=0.996503;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,30,255:10:0 0,15,156:5:0 +17 1440 . A 0 . DP=30;I16=12,16,0,0,1062,41028,0,0,1618,95282,0,0,550,12106,0,0;QS=3,0;MQSB=0.995699;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,255:9:0 0,12,144:4:0 +17 1441 . G 0 . DP=30;I16=13,17,0,0,1138,44104,0,0,1738,102482,0,0,574,12576,0,0;QS=3,0;MQSB=0.996503;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,30,244:10:0 0,12,137:4:0 +17 1442 . G 0 . DP=30;I16=13,17,0,0,1064,38534,0,0,1738,102482,0,0,580,12740,0,0;QS=3,0;MQSB=0.996503;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,30,242:10:0 0,12,128:4:0 +17 1443 . T 0 . DP=30;I16=12,17,0,0,1013,36225,0,0,1678,98882,0,0,568,12598,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,30,230:10:0 0,12,133:4:0 +17 1444 . A 0 . DP=30;I16=12,17,0,0,968,33936,0,0,1678,98882,0,0,569,12627,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,27,205:9:0 0,12,132:4:0 +17 1445 . T 0 . DP=30;I16=14,15,0,0,1053,39129,0,0,1678,98882,0,0,585,13161,0,0;QS=3,0;MQSB=0.999762;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,237:9:0 0,15,169:5:0 +17 1446 . T 0 . DP=30;I16=13,16,0,0,1051,38675,0,0,1678,98882,0,0,579,12951,0,0;QS=3,0;MQSB=0.997839;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,229:8:0 0,15,164:5:0 +17 1447 . G 0 . DP=30;I16=14,16,0,0,1110,42692,0,0,1738,102482,0,0,606,13612,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,27,229:9:0 0,15,157:5:0 +17 1448 . G 0 . DP=30;I16=13,16,0,0,1037,37759,0,0,1678,98882,0,0,585,13151,0,0;QS=3,0;MQSB=0.997839;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,217:8:0 0,15,150:5:0 +17 1449 . T 0 . DP=30;I16=14,16,0,0,1051,37869,0,0,1738,102482,0,0,612,13870,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,27,230:9:0 0,15,152:5:0 +17 1450 . A 0 . DP=29;I16=13,15,0,0,1039,38785,0,0,1649,98041,0,0,604,13842,0,0;QS=3,0;MQSB=0.956162;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,224:8:0 0,15,165:5:0 +17 1451 . T 0 . DP=29;I16=13,16,0,0,1046,38586,0,0,1709,101641,0,0,616,14042,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,228:8:0 0,15,158:5:0 +17 1452 . A 0 . DP=31;I16=14,16,0,0,1066,38696,0,0,1769,105241,0,0,604,13924,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,218:8:0 0,15,147:5:0 +17 1453 . T 0 . DP=31;I16=13,17,0,0,1107,42059,0,0,1769,105241,0,0,592,13444,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,199:7:0 0,15,165:5:0 +17 1454 . T 0 . DP=31;I16=14,17,0,0,1139,42711,0,0,1829,108841,0,0,617,14045,0,0;QS=3,0;MQSB=0.962133;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,234:8:0 0,15,166:5:0 +17 1455 . G 0 . DP=31;I16=13,17,0,0,1107,41765,0,0,1769,105241,0,0,592,13420,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,197:7:0 0,15,148:5:0 +17 1456 . T 0 . DP=31;I16=14,17,0,0,1139,42717,0,0,1829,108841,0,0,617,14069,0,0;QS=3,0;MQSB=0.962133;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,215:8:0 0,15,170:5:0 +17 1457 . G 0 . DP=31;I16=14,17,0,0,1129,42071,0,0,1829,108841,0,0,615,14019,0,0;QS=3,0;MQSB=0.962133;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,212:8:0 0,15,164:5:0 +17 1458 . T 0 . DP=31;I16=14,17,0,0,1101,40243,0,0,1829,108841,0,0,613,13997,0,0;QS=3,0;MQSB=0.962133;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,220:8:0 0,15,165:5:0 +17 1459 . C A, 0 . DP=31;I16=14,16,0,1,1164,45842,24,576,1769,105241,60,3600,608,13948,2,4;QS=2.87234,0.12766,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.962133;BQB=1;MQ0F=0 PL:DP:DV 0,54,255,54,255,255:18:0 0,24,224,24,224,224:8:0 9,0,135,21,138,152:5:1 +17 1460 . T 0 . DP=32;I16=15,17,0,0,1243,48813,0,0,1889,112441,0,0,605,13833,0,0;QS=3,0;MQSB=0.960687;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,240:8:0 0,15,170:5:0 +17 1461 . G 0 . DP=32;I16=15,17,0,0,1171,44033,0,0,1889,112441,0,0,600,13692,0,0;QS=3,0;MQSB=0.960687;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,224:8:0 0,15,157:5:0 +17 1462 . C 0 . DP=30;I16=14,15,0,0,1102,42216,0,0,1709,101641,0,0,579,13241,0,0;QS=3,0;MQSB=0.954405;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,202:7:0 0,9,112:3:0 +17 1463 . T 0 . DP=30;I16=15,15,0,0,1128,43348,0,0,1769,105241,0,0,592,13396,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,209:7:0 0,12,139:4:0 +17 1464 . G 0 . DP=31;I16=14,16,0,0,1095,40557,0,0,1769,105241,0,0,563,12665,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,186:6:0 0,15,144:5:0 +17 1465 . T 0 . DP=31;I16=15,16,0,0,1143,42557,0,0,1829,108841,0,0,584,13164,0,0;QS=3,0;MQSB=0.957006;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,204:7:0 0,15,166:5:0 +17 1466 . G 0 . DP=31;I16=15,16,0,0,1122,42294,0,0,1829,108841,0,0,580,13018,0,0;QS=3,0;MQSB=0.957006;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,206:7:0 0,15,163:5:0 +17 1467 . A 0 . DP=31;I16=14,16,0,0,1031,36341,0,0,1769,105241,0,0,569,12803,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,195:7:0 0,15,155:5:0 +17 1468 . A 0 . DP=30;I16=15,15,0,0,991,34477,0,0,1769,105241,0,0,573,12717,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,177:7:0 0,15,158:5:0 +17 1469 . C T, 0 . DP=31;I16=13,15,1,0,1013,37887,38,1444,1649,98041,60,3600,536,12106,9,81;QS=2.94025,0.0597484,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.954405;BQB=1;MQ0F=0 PL:DP:DV 0,16,255,51,255,255:18:1 0,18,178,18,178,178:6:0 0,15,160,15,160,160:5:0 +17 1470 . T 0 . DP=31;I16=16,15,0,0,1110,41070,0,0,1829,108841,0,0,567,12489,0,0;QS=3,0;MQSB=0.951229;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,210:7:0 0,15,165:5:0 +17 1471 . G 0 . DP=30;I16=16,14,0,0,1051,38425,0,0,1769,105241,0,0,564,12348,0,0;QS=3,0;MQSB=0.946202;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,192:7:0 0,12,128:4:0 +17 1472 . T 0 . DP=30;I16=16,14,0,0,1049,38097,0,0,1769,105241,0,0,561,12237,0,0;QS=3,0;MQSB=0.946202;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,200:7:0 0,12,134:4:0 +17 1473 . C 0 . DP=30;I16=16,14,0,0,1058,38526,0,0,1769,105241,0,0,558,12156,0,0;QS=3,0;MQSB=0.946202;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,175:7:0 0,12,140:4:0 +17 1474 . C 0 . DP=30;I16=16,14,0,0,1120,42756,0,0,1769,105241,0,0,555,12105,0,0;QS=3,0;MQSB=0.946202;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,202:7:0 0,12,141:4:0 +17 1475 . T 0 . DP=29;I16=14,14,0,0,1047,40395,0,0,1649,98041,0,0,537,11827,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,208:7:0 0,12,155:4:0 +17 1476 . T G, 0 . DP=31;I16=15,15,1,0,1056,37884,14,196,1769,105241,60,3600,566,12614,10,100;QS=2.944,0.056,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.951229;BQB=1;MQ0F=0 PL:DP:DV 0,57,255,57,255,255:19:0 0,9,177,21,180,183:8:1 0,12,140,12,140,140:4:0 +17 1477 . G 0 . DP=31;I16=16,15,0,0,1150,43390,0,0,1829,108841,0,0,574,12700,0,0;QS=3,0;MQSB=0.951229;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,217:8:0 0,12,138:4:0 +17 1478 . G 0 . DP=31;I16=14,15,0,0,1008,36638,0,0,1709,101641,0,0,542,11982,0,0;QS=3,0;MQSB=0.954405;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,208:8:0 0,9,109:3:0 +17 1479 . C 0 . DP=30;I16=15,15,0,0,1061,38671,0,0,1769,105241,0,0,564,12556,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,211:8:0 0,9,106:3:0 +17 1480 . C 0 . DP=30;I16=15,15,0,0,1083,40355,0,0,1769,105241,0,0,561,12531,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,220:8:0 0,9,103:3:0 +17 1481 . T 0 . DP=30;I16=15,15,0,0,1102,41308,0,0,1769,105241,0,0,558,12532,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,235:8:0 0,9,105:3:0 +17 1482 . G 0 . DP=29;I16=15,14,0,0,1044,38550,0,0,1709,101641,0,0,556,12558,0,0;QS=3,0;MQSB=0.947838;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,210:8:0 0,6,75:2:0 +17 1483 . T 0 . DP=31;I16=14,16,0,0,1042,37190,0,0,1769,105241,0,0,521,11919,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,215:7:0 0,9,100:3:0 +17 1484 . T 0 . DP=31;I16=15,16,0,0,1067,37837,0,0,1829,108841,0,0,547,12587,0,0;QS=3,0;MQSB=0.957006;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,24,216:8:0 0,9,106:3:0 +17 1485 . T 0 . DP=30;I16=15,15,0,0,1027,35863,0,0,1769,105241,0,0,549,12659,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,209:8:0 0,9,93:3:0 +17 1486 . G 0 . DP=29;I16=15,14,0,0,1089,41679,0,0,1709,101641,0,0,551,12707,0,0;QS=3,0;MQSB=0.947838;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,198:7:0 0,9,108:3:0 +17 1487 . G 0 . DP=28;I16=14,14,0,0,973,34723,0,0,1649,98041,0,0,554,12778,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,196:7:0 0,9,97:3:0 +17 1488 . T 0 . DP=28;I16=13,14,0,0,928,32432,0,0,1589,94441,0,0,532,12246,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,176:6:0 0,9,102:3:0 +17 1489 . G 0 . DP=27;I16=13,14,0,0,958,35292,0,0,1589,94441,0,0,535,12361,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,174:6:0 0,9,93:3:0 +17 1490 . A 0 . DP=27;I16=13,14,0,0,928,33108,0,0,1589,94441,0,0,538,12446,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,160:5:0 0,9,94:3:0 +17 1491 . C 0 . DP=27;I16=12,13,0,0,798,26812,0,0,1469,87241,0,0,499,11587,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,108:4:0 0,9,79:3:0 +17 1492 . G 0 . DP=27;I16=13,14,0,0,893,30927,0,0,1589,94441,0,0,543,12527,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,136:5:0 0,9,100:3:0 +17 1493 . G 0 . DP=27;I16=13,13,0,0,907,32761,0,0,1529,90841,0,0,520,11948,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,155:5:0 0,9,106:3:0 +17 1494 . G 0 . DP=27;I16=13,14,0,0,939,33599,0,0,1589,94441,0,0,547,12639,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,156:5:0 0,9,107:3:0 +17 1495 . T 0 . DP=26;I16=12,13,0,0,814,27700,0,0,1469,87241,0,0,524,12048,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,143:5:0 0,9,105:3:0 +17 1496 . G 0 . DP=26;I16=13,13,0,0,969,36751,0,0,1529,90841,0,0,550,12674,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,157:5:0 0,9,107:3:0 +17 1497 . A 0 . DP=27;I16=12,14,0,0,904,32740,0,0,1529,90841,0,0,525,12019,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,166:5:0 0,9,113:3:0 +17 1498 . G 0 . DP=27;I16=13,14,0,0,1002,37852,0,0,1589,94441,0,0,551,12635,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,153:5:0 0,9,112:3:0 +17 1499 . G 0 . DP=28;I16=14,14,0,0,973,34891,0,0,1649,98041,0,0,551,12599,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,146:5:0 0,9,108:3:0 +17 1500 . A 0 . DP=28;I16=14,14,0,0,1023,38115,0,0,1649,98041,0,0,552,12588,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,165:5:0 0,9,115:3:0 +17 1501 . G 0 . DP=28;I16=14,14,0,0,1051,40105,0,0,1649,98041,0,0,551,12505,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,163:5:0 0,9,100:3:0 +17 1502 . C 0 . DP=27;I16=13,14,0,0,963,35241,0,0,1589,94441,0,0,549,12351,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,140:5:0 0,9,105:3:0 +17 1503 . A 0 . DP=28;I16=14,14,0,0,1026,38252,0,0,1649,98041,0,0,546,12176,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,171:5:0 0,9,109:3:0 +17 1504 . G 0 . DP=28;I16=13,14,0,0,1052,41226,0,0,1589,94441,0,0,523,11591,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,163:5:0 0,9,111:3:0 +17 1505 . G 0 . DP=28;I16=14,13,0,0,959,35545,0,0,1589,94441,0,0,517,11295,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,155:5:0 0,9,114:3:0 +17 1506 . G 0 . DP=28;I16=14,14,0,0,1013,37355,0,0,1649,98041,0,0,540,11840,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,139:5:0 0,9,112:3:0 +17 1507 . A 0 . DP=28;I16=14,14,0,0,987,35217,0,0,1649,98041,0,0,538,11792,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,162:5:0 0,9,114:3:0 +17 1508 . C 0 . DP=28;I16=14,14,0,0,1033,38663,0,0,1649,98041,0,0,535,11727,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,137:5:0 0,9,112:3:0 +17 1509 . A 0 . DP=28;I16=15,13,0,0,1028,38610,0,0,1649,98041,0,0,529,11493,0,0;QS=3,0;MQSB=0.942064;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,12,128:4:0 0,9,122:3:0 +17 1510 . G 0 . DP=28;I16=15,13,0,0,1064,40824,0,0,1649,98041,0,0,524,11288,0,0;QS=3,0;MQSB=0.942064;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,12,132:4:0 0,9,111:3:0 +17 1511 . A 0 . DP=28;I16=15,13,0,0,976,34794,0,0,1649,98041,0,0,519,11113,0,0;QS=3,0;MQSB=0.942064;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,12,136:4:0 0,9,110:3:0 +17 1512 . A 0 . DP=28;I16=15,12,0,0,998,37460,0,0,1589,94441,0,0,489,10343,0,0;QS=3,0;MQSB=0.935229;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,142:4:0 0,9,110:3:0 +17 1513 . G 0 . DP=28;I16=14,13,0,0,1014,38940,0,0,1589,94441,0,0,497,10709,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,134:4:0 0,9,108:3:0 +17 1514 . G 0 . DP=28;I16=15,13,0,0,1054,39954,0,0,1649,98041,0,0,504,10768,0,0;QS=3,0;MQSB=0.942064;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,12,134:4:0 0,9,108:3:0 +17 1515 . G 0 . DP=28;I16=14,13,0,0,948,34152,0,0,1589,94441,0,0,488,10564,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,133:4:0 0,9,101:3:0 +17 1516 . T 0 . DP=27;I16=12,13,0,0,811,27385,0,0,1469,87241,0,0,472,10338,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,117:4:0 0,9,106:3:0 +17 1517 . C 0 . DP=27;I16=13,13,0,0,943,35153,0,0,1529,90841,0,0,478,10380,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,12,134:4:0 0,9,97:3:0 +17 1518 . C 0 . DP=28;I16=13,12,0,0,908,33852,0,0,1469,87241,0,0,427,9261,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,132:4:0 0,9,96:3:0 +17 1519 . T 0 . DP=28;I16=15,13,0,0,988,35808,0,0,1649,98041,0,0,475,10337,0,0;QS=3,0;MQSB=0.942064;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,154:5:0 0,9,110:3:0 +17 1520 . G 0 . DP=29;I16=16,13,0,0,1005,36307,0,0,1709,101641,0,0,470,10328,0,0;QS=3,0;MQSB=0.940317;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,18,150:6:0 0,9,104:3:0 +17 1521 . C 0 . DP=28;I16=16,12,0,0,900,30324,0,0,1649,98041,0,0,466,10300,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,164:6:0 0,9,88:3:0 +17 1522 . G 0 . DP=27;I16=15,10,0,0,784,25144,0,0,1469,87241,0,0,442,9956,0,0;QS=3,0;MQSB=0.9171;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,110:5:0 0,9,91:3:0 +17 1523 . T 0 . DP=27;I16=16,11,0,0,921,32001,0,0,1589,94441,0,0,457,10189,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,136:5:0 0,9,108:3:0 +17 1524 . G 0 . DP=27;I16=16,10,0,0,932,34140,0,0,1529,90841,0,0,453,10153,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,12,108:4:0 0,9,103:3:0 +17 1525 . C 0 . DP=27;I16=16,11,0,0,972,35704,0,0,1589,94441,0,0,473,10719,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,113:4:0 0,9,112:3:0 +17 1526 . C 0 . DP=25;I16=14,11,0,0,883,31843,0,0,1469,87241,0,0,470,10684,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,109:4:0 0,9,106:3:0 +17 1527 . C 0 . DP=24;I16=14,10,0,0,867,31999,0,0,1440,86400,0,0,466,10572,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,107:4:0 0,9,112:3:0 +17 1528 . T 0 . DP=23;I16=13,10,0,0,869,33133,0,0,1380,82800,0,0,463,10483,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,114:4:0 0,9,113:3:0 +17 1529 . G 0 . DP=23;I16=13,10,0,0,812,29432,0,0,1380,82800,0,0,459,10365,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,108:4:0 0,9,104:3:0 +17 1530 . C 0 . DP=24;I16=13,10,0,0,819,30073,0,0,1380,82800,0,0,446,10186,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,137:5:0 0,9,106:3:0 +17 1531 . C 0 . DP=24;I16=13,11,0,0,877,32969,0,0,1440,86400,0,0,452,10190,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,144:5:0 0,9,105:3:0 +17 1532 . T 0 . DP=24;I16=13,11,0,0,887,33721,0,0,1440,86400,0,0,449,10135,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,165:5:0 0,9,120:3:0 +17 1533 . T 0 . DP=23;I16=13,10,0,0,793,27987,0,0,1380,82800,0,0,447,10101,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,146:5:0 0,9,107:3:0 +17 1534 . C 0 . DP=23;I16=14,9,0,0,847,31627,0,0,1380,82800,0,0,446,10086,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,153:5:0 0,9,109:3:0 +17 1535 . A 0 . DP=23;I16=14,9,0,0,770,26604,0,0,1380,82800,0,0,444,9990,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,144:5:0 0,9,99:3:0 +17 1536 . C 0 . DP=24;I16=15,9,0,0,826,28984,0,0,1440,86400,0,0,442,9914,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,138:5:0 0,9,110:3:0 +17 1537 . A 0 . DP=24;I16=14,9,0,0,844,31384,0,0,1380,82800,0,0,416,9234,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,149:5:0 0,9,115:3:0 +17 1538 . A 0 . DP=24;I16=15,9,0,0,909,34727,0,0,1440,86400,0,0,440,9826,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,154:5:0 0,9,112:3:0 +17 1539 . G 0 . DP=24;I16=15,9,0,0,913,35327,0,0,1440,86400,0,0,439,9815,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,149:5:0 0,9,117:3:0 +17 1540 . C 0 . DP=23;I16=15,8,0,0,828,30260,0,0,1380,82800,0,0,438,9776,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,146:5:0 0,9,102:3:0 +17 1541 . C 0 . DP=23;I16=15,8,0,0,823,30615,0,0,1380,82800,0,0,437,9759,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,142:5:0 0,9,108:3:0 +17 1542 . C 0 . DP=25;I16=16,8,0,0,893,33843,0,0,1440,86400,0,0,435,9715,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,147:5:0 0,12,131:4:0 +17 1543 . C 0 . DP=25;I16=16,8,0,0,880,33206,0,0,1440,86400,0,0,434,9696,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,141:5:0 0,12,136:4:0 +17 1544 . T 0 . DP=25;I16=16,8,0,0,899,34405,0,0,1440,86400,0,0,431,9603,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,150:5:0 0,12,148:4:0 +17 1545 . G 0 . DP=25;I16=16,8,0,0,874,32636,0,0,1440,86400,0,0,428,9536,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,146:5:0 0,12,129:4:0 +17 1546 . G 0 . DP=24;I16=15,8,0,0,796,28796,0,0,1380,82800,0,0,425,9443,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,130:5:0 0,9,110:3:0 +17 1547 . A 0 . DP=23;I16=15,8,0,0,837,30945,0,0,1380,82800,0,0,448,9996,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,176:6:0 0,9,112:3:0 +17 1548 . A 0 . DP=23;I16=14,8,0,0,812,30830,0,0,1320,79200,0,0,421,9319,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,173:5:0 0,9,115:3:0 +17 1549 . G 0 . DP=23;I16=15,8,0,0,870,33642,0,0,1380,82800,0,0,444,9912,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,174:6:0 0,9,114:3:0 +17 1550 . G 0 . DP=23;I16=15,8,0,0,790,28502,0,0,1380,82800,0,0,442,9900,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,154:6:0 0,9,109:3:0 +17 1551 . A 0 . DP=23;I16=15,8,0,0,802,28596,0,0,1380,82800,0,0,440,9908,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,173:6:0 0,9,107:3:0 +17 1552 . A 0 . DP=21;I16=14,7,0,0,792,30156,0,0,1260,75600,0,0,438,9836,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,196:6:0 0,9,110:3:0 +17 1553 . A 0 . DP=21;I16=13,7,0,0,738,28112,0,0,1200,72000,0,0,411,9159,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,251:11:0 0,18,192:6:0 0,9,115:3:0 +17 1554 . G 0 . DP=21;I16=14,7,0,0,763,28221,0,0,1260,75600,0,0,434,9752,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,171:6:0 0,9,101:3:0 +17 1555 . T 0 . DP=21;I16=14,7,0,0,726,26234,0,0,1260,75600,0,0,432,9740,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,252:12:0 0,18,169:6:0 0,9,108:3:0 +17 1556 . T 0 . DP=21;I16=14,7,0,0,745,26971,0,0,1260,75600,0,0,429,9697,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,253:12:0 0,18,177:6:0 0,9,110:3:0 +17 1557 . G 0 . DP=22;I16=15,7,0,0,801,29689,0,0,1320,79200,0,0,426,9672,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,166:6:0 0,9,101:3:0 +17 1558 . T 0 . DP=22;I16=15,6,0,0,720,25620,0,0,1260,75600,0,0,404,9244,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,131:5:0 0,9,112:3:0 +17 1559 . T 0 . DP=22;I16=15,7,0,0,712,24690,0,0,1320,79200,0,0,417,9439,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,248:13:0 0,18,158:6:0 0,9,103:3:0 +17 1560 . T 0 . DP=21;I16=14,7,0,0,736,26560,0,0,1260,75600,0,0,412,9284,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,251:12:0 0,18,170:6:0 0,9,112:3:0 +17 1561 . T 0 . DP=21;I16=14,7,0,0,706,24776,0,0,1260,75600,0,0,406,9102,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,241:12:0 0,18,174:6:0 0,9,106:3:0 +17 1562 . G 0 . DP=21;I16=14,7,0,0,765,28655,0,0,1260,75600,0,0,399,8893,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,181:6:0 0,9,108:3:0 +17 1563 . G 0 . DP=22;I16=13,7,0,0,713,26255,0,0,1200,72000,0,0,360,8176,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,147:5:0 0,9,108:3:0 +17 1564 . G 0 . DP=22;I16=13,8,0,0,721,25457,0,0,1260,75600,0,0,368,8218,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,173:6:0 0,9,95:3:0 +17 1565 . A 0 . DP=21;I16=14,7,0,0,724,25888,0,0,1260,75600,0,0,380,8352,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,162:6:0 0,6,71:2:0 +17 1566 . T 0 . DP=21;I16=13,7,0,0,698,25286,0,0,1200,72000,0,0,364,8086,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,143:5:0 0,6,78:2:0 +17 1567 . C 0 . DP=20;I16=12,6,0,0,652,24422,0,0,1080,64800,0,0,351,7881,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,104:3:0 0,6,72:2:0 +17 1568 . T 0 . DP=20;I16=13,7,0,0,711,26125,0,0,1200,72000,0,0,363,7871,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,157:5:0 0,6,74:2:0 +17 1569 . C 0 . DP=19;I16=12,6,0,0,676,25850,0,0,1080,64800,0,0,351,7669,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,128:4:0 0,6,76:2:0 +17 1570 . T 0 . DP=19;I16=12,7,0,0,700,26750,0,0,1140,68400,0,0,353,7583,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,149:5:0 0,6,71:2:0 +17 1571 . G 0 . DP=19;I16=12,6,0,0,639,23361,0,0,1080,64800,0,0,343,7441,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,125:4:0 0,6,70:2:0 +17 1572 . C 0 . DP=19;I16=11,6,0,0,640,24568,0,0,1020,61200,0,0,328,7202,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,125:4:0 0,6,70:2:0 +17 1573 . A 0 . DP=19;I16=11,4,0,0,565,21475,0,0,900,54000,0,0,304,6900,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,132:4:0 0,3,40:1:0 +17 1574 . C 0 . DP=19;I16=12,5,0,0,636,24076,0,0,1020,61200,0,0,318,6948,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,128:4:0 0,3,38:1:0 +17 1575 . C 0 . DP=19;I16=11,6,0,0,610,22742,0,0,1020,61200,0,0,296,6272,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,125:4:0 0,6,71:2:0 +17 1576 . C 0 . DP=19;I16=12,6,0,0,675,25821,0,0,1080,64800,0,0,315,6785,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,133:4:0 0,6,78:2:0 +17 1577 . T 0 . DP=17;I16=11,6,0,0,650,25330,0,0,1020,61200,0,0,310,6692,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,118:3:0 0,6,77:2:0 +17 1578 . C 0 . DP=17;I16=10,6,0,0,622,24364,0,0,960,57600,0,0,279,5943,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,84:2:0 0,6,77:2:0 +17 1579 . A 0 . DP=17;I16=11,6,0,0,596,22326,0,0,1020,61200,0,0,298,6464,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,116:3:0 0,6,80:2:0 +17 1580 . G 0 . DP=17;I16=11,6,0,0,651,25195,0,0,1020,61200,0,0,292,6380,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,109:3:0 0,6,77:2:0 +17 1581 . C 0 . DP=17;I16=11,6,0,0,586,21418,0,0,1020,61200,0,0,286,6316,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,103:3:0 0,6,71:2:0 +17 1582 . C 0 . DP=18;I16=11,7,0,0,639,23491,0,0,1080,64800,0,0,280,6272,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,109:3:0 0,6,75:2:0 +17 1583 . T 0 . DP=16;I16=10,6,0,0,591,22349,0,0,960,57600,0,0,276,6196,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,112:3:0 0,6,74:2:0 +17 1584 . G 0 . DP=15;I16=10,5,0,0,563,21283,0,0,900,54000,0,0,272,6086,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,105:3:0 0,3,39:1:0 +17 1585 . G 0 . DP=16;I16=10,5,0,0,494,17160,0,0,900,54000,0,0,251,5703,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,244:11:0 0,9,103:3:0 0,3,30:1:0 +17 1586 . A 0 . DP=15;I16=10,3,0,0,470,17200,0,0,780,46800,0,0,237,5273,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,223:10:0 0,6,79:2:0 0,3,42:1:0 +17 1587 . C 0 . DP=15;I16=11,4,0,0,508,17900,0,0,900,54000,0,0,264,5852,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,247:11:0 0,9,94:3:0 0,3,31:1:0 +17 1588 . A 0 . DP=15;I16=11,4,0,0,511,17939,0,0,900,54000,0,0,262,5806,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,232:11:0 0,9,105:3:0 0,3,41:1:0 +17 1589 . A 0 . DP=15;I16=11,4,0,0,536,19584,0,0,900,54000,0,0,259,5725,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,249:11:0 0,9,106:3:0 0,3,42:1:0 +17 1590 . C 0 . DP=15;I16=10,5,0,0,514,18228,0,0,900,54000,0,0,257,5657,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,231:10:0 0,9,104:3:0 0,6,71:2:0 +17 1591 . T 0 . DP=15;I16=10,5,0,0,515,18559,0,0,900,54000,0,0,256,5602,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,241:10:0 0,9,85:3:0 0,6,73:2:0 +17 1592 . T 0 . DP=15;I16=10,5,0,0,503,17345,0,0,900,54000,0,0,255,5561,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,225:10:0 0,9,107:3:0 0,6,62:2:0 +17 1593 . G 0 . DP=15;I16=10,5,0,0,540,19930,0,0,900,54000,0,0,254,5534,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,9,106:3:0 0,6,60:2:0 +17 1594 . T 0 . DP=15;I16=10,5,0,0,535,19445,0,0,900,54000,0,0,252,5472,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,234:10:0 0,9,106:3:0 0,6,80:2:0 +17 1595 . G 0 . DP=15;I16=10,4,0,0,494,17940,0,0,840,50400,0,0,225,4801,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,213:9:0 0,9,105:3:0 0,6,69:2:0 +17 1596 . C 0 . DP=15;I16=10,4,0,0,479,17011,0,0,840,50400,0,0,233,5151,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,200:9:0 0,9,111:3:0 0,6,74:2:0 +17 1597 . C 0 . DP=15;I16=10,5,0,0,489,16941,0,0,900,54000,0,0,245,5285,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,195:9:0 0,12,127:4:0 0,6,73:2:0 +17 1598 . C 0 . DP=15;I16=10,5,0,0,514,18282,0,0,900,54000,0,0,244,5240,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,207:9:0 0,12,133:4:0 0,6,68:2:0 +17 1599 . A 0 . DP=14;I16=8,5,0,0,436,15330,0,0,780,46800,0,0,225,4851,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,182:8:0 0,9,103:3:0 0,6,76:2:0 +17 1600 . T 0 . DP=13;I16=8,5,0,0,456,16430,0,0,780,46800,0,0,226,4876,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,193:8:0 0,9,105:3:0 0,6,79:2:0 +17 1601 . C 0 . DP=13;I16=8,4,0,0,431,15861,0,0,720,43200,0,0,208,4554,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,171:7:0 0,9,108:3:0 0,6,78:2:0 +17 1602 . T 0 . DP=13;I16=7,5,0,0,439,16867,0,0,720,43200,0,0,228,4968,0,0;QS=3,0;MQSB=0.95494;MQ0F=0 PL:DP:DV 0,21,179:7:0 0,9,115:3:0 0,6,85:2:0 +17 1603 . G 0 . DP=12;I16=7,5,0,0,455,17407,0,0,720,43200,0,0,230,5034,0,0;QS=3,0;MQSB=0.95494;MQ0F=0 PL:DP:DV 0,21,202:7:0 0,9,111:3:0 0,6,75:2:0 +17 1604 . G 0 . DP=12;I16=7,5,0,0,362,11620,0,0,720,43200,0,0,232,5112,0,0;QS=3,0;MQSB=0.95494;MQ0F=0 PL:DP:DV 0,21,163:7:0 0,9,84:3:0 0,6,66:2:0 +17 1605 . T 0 . DP=12;I16=7,5,0,0,410,14230,0,0,720,43200,0,0,234,5202,0,0;QS=3,0;MQSB=0.95494;MQ0F=0 PL:DP:DV 0,21,190:7:0 0,9,97:3:0 0,6,61:2:0 +17 1606 . G 0 . DP=12;I16=7,4,0,0,370,12738,0,0,660,39600,0,0,211,4679,0,0;QS=3,0;MQSB=0.964642;MQ0F=0 PL:DP:DV 0,18,165:6:0 0,9,91:3:0 0,6,56:2:0 +17 1607 . A 0 . DP=12;I16=7,4,0,0,337,11369,0,0,660,39600,0,0,226,5222,0,0;QS=3,0;MQSB=0.964642;MQ0F=0 PL:DP:DV 0,21,161:7:0 0,6,70:2:0 0,6,55:2:0 +17 1608 . C 0 . DP=12;I16=7,4,0,0,366,12898,0,0,660,39600,0,0,211,4727,0,0;QS=3,0;MQSB=0.964642;MQ0F=0 PL:DP:DV 0,18,141:6:0 0,9,111:3:0 0,6,62:2:0 +17 1609 . C 0 . DP=11;I16=6,5,0,0,365,12889,0,0,660,39600,0,0,237,5393,0,0;QS=3,0;MQSB=0.950952;MQ0F=0 PL:DP:DV 0,18,149:6:0 0,9,110:3:0 0,6,71:2:0 +17 1610 . C 0 . DP=11;I16=5,5,0,0,313,10713,0,0,600,36000,0,0,213,4819,0,0;QS=3,0;MQSB=0.952347;MQ0F=0 PL:DP:DV 0,15,127:5:0 0,9,106:3:0 0,6,57:2:0 +17 1611 . C 0 . DP=11;I16=6,5,0,0,398,14904,0,0,660,39600,0,0,238,5454,0,0;QS=3,0;MQSB=0.950952;MQ0F=0 PL:DP:DV 0,18,180:6:0 0,9,110:3:0 0,6,67:2:0 +17 1612 . T 0 . DP=11;I16=6,5,0,0,409,15421,0,0,660,39600,0,0,238,5472,0,0;QS=3,0;MQSB=0.950952;MQ0F=0 PL:DP:DV 0,18,174:6:0 0,9,107:3:0 0,6,83:2:0 +17 1613 . C 0 . DP=11;I16=6,5,0,0,372,12904,0,0,660,39600,0,0,238,5498,0,0;QS=3,0;MQSB=0.950952;MQ0F=0 PL:DP:DV 0,18,169:6:0 0,9,99:3:0 0,6,63:2:0 +17 1614 . A 0 . DP=11;I16=6,5,0,0,353,12139,0,0,660,39600,0,0,238,5532,0,0;QS=3,0;MQSB=0.950952;MQ0F=0 PL:DP:DV 0,18,147:6:0 0,9,98:3:0 0,6,69:2:0 +17 1615 . C 0 . DP=11;I16=6,5,0,0,366,13080,0,0,660,39600,0,0,238,5574,0,0;QS=3,0;MQSB=0.950952;MQ0F=0 PL:DP:DV 0,18,171:6:0 0,9,105:3:0 0,6,51:2:0 +17 1616 . T 0 . DP=11;I16=6,3,0,0,348,13606,0,0,540,32400,0,0,187,4323,0,0;QS=3,0;MQSB=0.924584;MQ0F=0 PL:DP:DV 0,15,159:5:0 0,9,105:3:0 0,3,42:1:0 +17 1617 . C 0 . DP=12;I16=6,3,0,0,330,12316,0,0,540,32400,0,0,185,4279,0,0;QS=3,0;MQSB=0.924584;MQ0F=0 PL:DP:DV 0,15,146:5:0 0,9,105:3:0 0,3,42:1:0 +17 1618 . A 0 . DP=12;I16=5,6,0,0,385,14199,0,0,629,36841,0,0,244,5636,0,0;QS=3,0;MQSB=0.891517;MQ0F=0 PL:DP:DV 0,18,151:6:0 0,9,93:3:0 0,6,81:2:0 +17 1619 . G 0 . DP=11;I16=5,6,0,0,377,13119,0,0,629,36841,0,0,242,5544,0,0;QS=3,0;MQSB=0.891517;MQ0F=0 PL:DP:DV 0,18,166:6:0 0,9,84:3:0 0,6,67:2:0 +17 1620 . C 0 . DP=11;I16=5,5,0,0,323,10965,0,0,569,33241,0,0,215,4839,0,0;QS=3,0;MQSB=0.857112;MQ0F=0 PL:DP:DV 0,15,142:5:0 0,9,78:3:0 0,6,56:2:0 +17 1621 . C 0 . DP=12;I16=5,7,0,0,363,11779,0,0,689,40441,0,0,263,6021,0,0;QS=3,0;MQSB=0.896474;MQ0F=0 PL:DP:DV 0,21,174:7:0 0,9,80:3:0 0,6,56:2:0 +17 1622 . A 0 . DP=12;I16=5,7,0,0,365,12105,0,0,689,40441,0,0,261,5965,0,0;QS=3,0;MQSB=0.896474;MQ0F=0 PL:DP:DV 0,21,176:7:0 0,9,81:3:0 0,6,52:2:0 +17 1623 . C 0 . DP=12;I16=5,5,0,0,325,10979,0,0,569,33241,0,0,208,4620,0,0;QS=3,0;MQSB=0.857112;MQ0F=0 PL:DP:DV 0,18,155:6:0 0,9,84:3:0 0,3,37:1:0 +17 1624 . C 0 . DP=12;I16=4,6,0,0,336,11718,0,0,569,33241,0,0,211,4799,0,0;QS=3,0;MQSB=0.895781;MQ0F=0 PL:DP:DV 0,18,162:6:0 0,9,88:3:0 0,3,39:1:0 +17 1625 . A 0 . DP=12;I16=4,7,0,0,375,13503,0,0,629,36841,0,0,234,5386,0,0;QS=3,0;MQSB=0.924449;MQ0F=0 PL:DP:DV 0,18,158:6:0 0,9,93:3:0 0,6,80:2:0 +17 1626 . G 0 . DP=12;I16=5,7,0,0,358,11490,0,0,689,40441,0,0,249,5645,0,0;QS=3,0;MQSB=0.896474;MQ0F=0 PL:DP:DV 0,21,158:7:0 0,9,83:3:0 0,6,63:2:0 +17 1627 . A 0 . DP=12;I16=5,7,0,0,363,11609,0,0,689,40441,0,0,246,5590,0,0;QS=3,0;MQSB=0.896474;MQ0F=0 PL:DP:DV 0,21,165:7:0 0,9,75:3:0 0,6,72:2:0 +17 1628 . C 0 . DP=12;I16=5,7,0,0,357,11583,0,0,689,40441,0,0,243,5545,0,0;QS=3,0;MQSB=0.896474;MQ0F=0 PL:DP:DV 0,21,165:7:0 0,9,80:3:0 0,6,57:2:0 +17 1629 . T 0 . DP=13;I16=6,7,0,0,451,16079,0,0,749,44041,0,0,240,5510,0,0;QS=3,0;MQSB=0.899815;MQ0F=0 PL:DP:DV 0,21,187:7:0 0,12,120:4:0 0,6,79:2:0 +17 1630 . T 0 . DP=13;I16=6,7,0,0,403,13323,0,0,749,44041,0,0,237,5435,0,0;QS=3,0;MQSB=0.899815;MQ0F=0 PL:DP:DV 0,21,169:7:0 0,12,111:4:0 0,6,73:2:0 +17 1631 . C 0 . DP=12;I16=6,5,0,0,354,12046,0,0,660,39600,0,0,210,4744,0,0;QS=3,0;MQSB=0.950952;MQ0F=0 PL:DP:DV 0,21,184:7:0 0,6,67:2:0 0,6,61:2:0 +17 1632 . C 0 . DP=13;I16=6,7,0,0,387,12175,0,0,749,44041,0,0,232,5262,0,0;QS=3,0;MQSB=0.899815;MQ0F=0 PL:DP:DV 0,24,188:8:0 0,9,82:3:0 0,6,61:2:0 +17 1633 . A 0 . DP=13;I16=6,7,0,0,404,13272,0,0,749,44041,0,0,230,5166,0,0;QS=3,0;MQSB=0.899815;MQ0F=0 PL:DP:DV 0,24,183:8:0 0,9,86:3:0 0,6,73:2:0 +17 1634 . C 0 . DP=13;I16=6,6,0,0,328,9716,0,0,689,40441,0,0,203,4457,0,0;QS=3,0;MQSB=0.864013;MQ0F=0 PL:DP:DV 0,21,151:7:0 0,9,80:3:0 0,6,59:2:0 +17 1635 . G 0 . DP=14;I16=6,8,0,0,419,12831,0,0,809,47641,0,0,226,5010,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,24,180:8:0 0,12,108:4:0 0,6,59:2:0 +17 1636 . A 0 . DP=14;I16=6,8,0,0,418,13400,0,0,809,47641,0,0,225,4951,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,24,179:8:0 0,12,110:4:0 0,6,66:2:0 +17 1637 . C 0 . DP=14;I16=6,8,0,0,422,13498,0,0,809,47641,0,0,224,4906,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,24,185:8:0 0,12,110:4:0 0,6,60:2:0 +17 1638 . A 0 . DP=17;I16=9,7,0,0,513,17167,0,0,929,54841,0,0,216,4790,0,0;QS=3,0;MQSB=0.892753;MQ0F=0 PL:DP:DV 0,24,191:8:0 0,18,149:6:0 0,6,78:2:0 +17 1639 . G 0 . DP=17;I16=9,8,0,0,552,18844,0,0,989,58441,0,0,223,4765,0,0;QS=3,0;MQSB=0.91051;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,18,150:6:0 0,6,68:2:0 +17 1640 . G 0 . DP=17;I16=8,6,0,0,414,13296,0,0,809,47641,0,0,171,3467,0,0;QS=3,0;MQSB=0.875173;MQ0F=0 PL:DP:DV 0,18,150:6:0 0,18,151:6:0 0,6,51:2:0 +17 1641 . C 0 . DP=18;I16=9,8,0,0,511,16289,0,0,989,58441,0,0,225,4709,0,0;QS=3,0;MQSB=0.91051;MQ0F=0 PL:DP:DV 0,27,188:9:0 0,18,167:6:0 0,6,65:2:0 +17 1642 . T 0 . DP=17;I16=8,7,0,0,519,18513,0,0,869,51241,0,0,217,4613,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,18,170:6:0 0,18,168:6:0 0,9,102:3:0 +17 1643 . C 0 . DP=16;I16=7,9,0,0,508,16910,0,0,929,54841,0,0,255,5361,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,24,193:8:0 0,18,169:6:0 0,6,56:2:0 +17 1644 . C 0 . DP=15;I16=6,9,0,0,514,18056,0,0,869,51241,0,0,259,5401,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,21,209:7:0 0,18,165:6:0 0,6,54:2:0 +17 1645 . A 0 . DP=15;I16=6,9,0,0,520,18852,0,0,869,51241,0,0,263,5457,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,21,213:7:0 0,18,173:6:0 0,6,49:2:0 +17 1646 . G 0 . DP=15;I16=6,7,0,0,440,15526,0,0,780,46800,0,0,217,4279,0,0;QS=3,0;MQSB=0.961166;MQ0F=0 PL:DP:DV 0,18,185:6:0 0,15,148:5:0 0,6,48:2:0 +17 1647 . C 0 . DP=15;I16=6,9,0,0,433,13883,0,0,869,51241,0,0,271,5617,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,21,190:7:0 0,18,139:6:0 0,6,35:2:0 +17 1648 . C 0 . DP=15;I16=6,9,0,0,495,16965,0,0,869,51241,0,0,275,5721,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,21,203:7:0 0,18,159:6:0 0,6,44:2:0 +17 1649 . T 0 . DP=15;I16=6,9,0,0,516,18122,0,0,869,51241,0,0,279,5841,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,21,187:7:0 0,18,182:6:0 0,6,56:2:0 +17 1650 . C 0 . DP=15;I16=6,7,0,0,405,13551,0,0,749,44041,0,0,240,5028,0,0;QS=3,0;MQSB=0.899815;MQ0F=0 PL:DP:DV 0,18,161:6:0 0,18,169:6:0 0,3,13:1:0 +17 1651 . G 0 . DP=17;I16=5,9,0,0,424,13328,0,0,778,44882,0,0,249,5335,0,0;QS=3,0;MQSB=0.965069;MQ0F=0 PL:DP:DV 0,18,150:6:0 0,15,128:5:0 0,9,86:3:0 +17 1652 . G 0 . DP=18;I16=7,9,0,0,532,18602,0,0,898,52082,0,0,267,5673,0,0;QS=3,0;MQSB=0.994413;MQ0F=0 PL:DP:DV 0,24,212:8:0 0,18,168:6:0 0,6,54:2:0 +17 1653 . C 0 . DP=18;I16=8,10,0,0,581,19565,0,0,1018,59282,0,0,300,6490,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,24,208:8:0 0,21,175:7:0 0,9,82:3:0 +17 1654 . A T, 0 . DP=18;I16=8,9,0,1,516,16718,15,225,958,55682,60,3600,285,6219,22,484;QS=2.93213,0.0678733,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.99606;BQB=1;MQ0F=0 PL:DP:DV 0,9,155,21,158,162:8:1 0,21,179,21,179,179:7:0 0,9,78,9,78,78:3:0 +17 1655 . C 0 . DP=18;I16=8,10,0,0,565,19017,0,0,1018,59282,0,0,313,6887,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,24,198:8:0 0,21,180:7:0 0,9,79:3:0 +17 1656 . C 0 . DP=19;I16=9,9,0,0,557,18013,0,0,1018,59282,0,0,295,6515,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,202:8:0 0,21,165:7:0 0,9,80:3:0 +17 1657 . T A, 0 . DP=18;I16=8,9,0,1,580,20362,15,225,989,58441,29,841,301,6641,25,625;QS=2.93243,0.0675676,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.99606;BQB=1;MQ0F=0 PL:DP:DV 0,24,206,24,206,206:8:0 0,6,158,18,161,165:7:1 0,9,85,9,85,85:3:0 +17 1658 . T 0 . DP=19;I16=8,10,0,0,573,19127,0,0,1018,59282,0,0,332,7412,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,24,187:8:0 0,21,189:7:0 0,9,91:3:0 +17 1659 . C 0 . DP=20;I16=8,10,0,0,609,21517,0,0,1049,62041,0,0,338,7578,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,24,219:8:0 0,21,189:7:0 0,9,80:3:0 +17 1660 . A 0 . DP=21;I16=8,11,0,0,641,23219,0,0,1078,62882,0,0,385,8901,0,0;QS=3,0;MQSB=0.992359;MQ0F=0 PL:DP:DV 0,21,172:7:0 0,24,219:8:0 0,12,127:4:0 +17 1661 . G 0 . DP=21;I16=7,13,0,0,639,21739,0,0,1107,63723,0,0,412,9598,0,0;QS=3,0;MQSB=0.999215;MQ0F=0 PL:DP:DV 0,24,209:8:0 0,24,193:8:0 0,12,98:4:0 +17 1662 . C 0 . DP=21;I16=8,12,0,0,641,21423,0,0,1107,63723,0,0,407,9465,0,0;QS=3,0;MQSB=0.988166;MQ0F=0 PL:DP:DV 0,21,192:7:0 0,27,211:9:0 0,12,100:4:0 +17 1663 . C 0 . DP=20;I16=7,11,0,0,577,19507,0,0,1018,59282,0,0,394,9204,0,0;QS=3,0;MQSB=0.983729;MQ0F=0 PL:DP:DV 0,21,178:7:0 0,21,192:7:0 0,12,101:4:0 +17 1664 . A C, 0 . DP=20;I16=6,10,0,1,530,17982,13,169,898,52082,29,841,358,8422,25,625;QS=2.93953,0.0604651,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.998738;BQB=1;MQ0F=0 PL:DP:DV 0,18,167,18,167,167:6:0 0,7,154,18,157,159:7:1 0,12,109,12,109,109:4:0 +17 1665 . T C, 0 . DP=20;I16=7,11,1,1,592,20170,58,1924,1018,59282,89,4441,396,9188,39,821;QS=2.5913,0.408696,0;VDB=0.1;SGB=0.346553;RPB=0.222222;MQB=0.611111;MQSB=0.988166;BQB=0.944444;MQ0F=0 PL:DP:DV 0,21,185,21,185,185:7:0 0,27,222,27,222,222:9:0 35,0,51,41,57,90:4:2 +17 1666 . G 0 . DP=20;I16=8,12,0,0,614,19760,0,0,1107,63723,0,0,435,9947,0,0;QS=3,0;MQSB=0.988166;MQ0F=0 PL:DP:DV 0,21,173:7:0 0,27,206:9:0 0,12,111:4:0 +17 1667 . G 0 . DP=20;I16=8,11,0,0,617,21033,0,0,1078,62882,0,0,410,9276,0,0;QS=3,0;MQSB=0.992359;MQ0F=0 PL:DP:DV 0,21,183:7:0 0,24,195:8:0 0,12,115:4:0 +17 1668 . A 0 . DP=20;I16=7,10,0,0,570,19908,0,0,958,55682,0,0,369,8365,0,0;QS=3,0;MQSB=0.989343;MQ0F=0 PL:DP:DV 0,18,158:6:0 0,21,186:7:0 0,12,124:4:0 +17 1669 . C 0 . DP=20;I16=8,12,0,0,640,21336,0,0,1107,63723,0,0,435,9857,0,0;QS=3,0;MQSB=0.988166;MQ0F=0 PL:DP:DV 0,21,172:7:0 0,27,216:9:0 0,12,115:4:0 +17 1670 . A 0 . DP=23;I16=9,13,0,0,765,27363,0,0,1258,73682,0,0,410,9234,0,0;QS=3,0;MQSB=0.991121;MQ0F=0 PL:DP:DV 0,27,215:9:0 0,27,233:9:0 0,12,129:4:0 +17 1671 . G 0 . DP=23;I16=9,13,0,0,703,23631,0,0,1258,73682,0,0,412,9206,0,0;QS=3,0;MQSB=0.991121;MQ0F=0 PL:DP:DV 0,27,214:9:0 0,27,210:9:0 0,12,106:4:0 +17 1672 . T 0 . DP=23;I16=9,13,0,0,724,24700,0,0,1258,73682,0,0,414,9202,0,0;QS=3,0;MQSB=0.991121;MQ0F=0 PL:DP:DV 0,27,203:9:0 0,27,232:9:0 0,12,111:4:0 +17 1673 . T 0 . DP=25;I16=8,13,0,0,719,25183,0,0,1198,70082,0,0,372,8248,0,0;QS=3,0;MQSB=0.983744;MQ0F=0 PL:DP:DV 0,27,221:9:0 0,24,212:8:0 0,12,112:4:0 +17 1674 . C 0 . DP=25;I16=8,14,0,0,755,26561,0,0,1289,76441,0,0,389,8417,0,0;QS=3,0;MQSB=0.892142;MQ0F=0 PL:DP:DV 0,33,244:11:0 0,21,206:7:0 0,12,96:4:0 +17 1675 . C 0 . DP=25;I16=9,15,0,0,705,22355,0,0,1347,78123,0,0,447,9897,0,0;QS=3,0;MQSB=0.996008;MQ0F=0 PL:DP:DV 0,33,222:11:0 0,30,212:10:0 0,9,65:3:0 +17 1676 . G 0 . DP=25;I16=6,15,0,0,660,21708,0,0,1167,67323,0,0,383,8265,0,0;QS=3,0;MQSB=0.993205;MQ0F=0 PL:DP:DV 0,33,222:11:0 0,21,170:7:0 0,9,96:3:0 +17 1677 . C 0 . DP=25;I16=9,13,0,0,681,22869,0,0,1289,76441,0,0,394,8510,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,33,225:11:0 0,24,198:8:0 0,9,74:3:0 +17 1678 . C 0 . DP=25;I16=9,15,0,0,775,26785,0,0,1347,78123,0,0,438,9496,0,0;QS=3,0;MQSB=0.996008;MQ0F=0 PL:DP:DV 0,33,235:11:0 0,30,231:10:0 0,9,83:3:0 +17 1679 . A 0 . DP=25;I16=8,15,0,0,762,27552,0,0,1287,74523,0,0,412,8858,0,0;QS=3,0;MQSB=0.999479;MQ0F=0 PL:DP:DV 0,33,235:11:0 0,27,219:9:0 0,9,106:3:0 +17 1680 . G 0 . DP=26;I16=9,17,0,0,843,29213,0,0,1467,85323,0,0,459,10021,0,0;QS=3,0;MQSB=0.999637;MQ0F=0 PL:DP:DV 0,33,253:11:0 0,33,232:11:0 0,12,108:4:0 +17 1681 . C 0 . DP=26;I16=8,15,0,0,681,21293,0,0,1318,77282,0,0,407,8999,0,0;QS=3,0;MQSB=0.974802;MQ0F=0 PL:DP:DV 0,33,223:11:0 0,27,191:9:0 0,9,69:3:0 +17 1682 . G 0 . DP=25;I16=9,16,0,0,728,22560,0,0,1407,81723,0,0,455,9877,0,0;QS=3,0;MQSB=0.998399;MQ0F=0 PL:DP:DV 0,30,222:10:0 0,33,208:11:0 0,12,98:4:0 +17 1683 . T 0 . DP=25;I16=8,15,0,0,807,29159,0,0,1287,74523,0,0,403,8567,0,0;QS=3,0;MQSB=0.999479;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,30,235:10:0 0,9,91:3:0 +17 1684 . T 0 . DP=25;I16=8,15,0,0,802,28774,0,0,1318,77282,0,0,438,9612,0,0;QS=3,0;MQSB=0.974802;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,30,237:10:0 0,12,107:4:0 +17 1685 . G 0 . DP=24;I16=8,14,0,0,759,27319,0,0,1258,73682,0,0,413,8999,0,0;QS=3,0;MQSB=0.979255;MQ0F=0 PL:DP:DV 0,24,216:8:0 0,30,242:10:0 0,12,110:4:0 +17 1686 . C 0 . DP=24;I16=8,15,0,0,793,28073,0,0,1318,77282,0,0,438,9656,0,0;QS=3,0;MQSB=0.974802;MQ0F=0 PL:DP:DV 0,27,225:9:0 0,30,241:10:0 0,12,103:4:0 +17 1687 . C 0 . DP=24;I16=7,14,0,0,741,26765,0,0,1198,70082,0,0,388,8458,0,0;QS=3,0;MQSB=0.966484;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,27,229:9:0 0,12,106:4:0 +17 1688 . C 0 . DP=24;I16=8,15,0,0,794,28736,0,0,1318,77282,0,0,431,9605,0,0;QS=3,0;MQSB=0.974802;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,30,221:10:0 0,12,120:4:0 +17 1689 . T A, 0 . DP=24;I16=8,15,0,1,805,29443,33,1089,1287,74523,60,3600,421,9311,25,625;QS=2.74419,0.255814,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,27,224,27,224,224:9:0 0,33,255,33,255,255:11:0 21,0,79,30,82,106:4:1 +17 1690 . C 0 . DP=24;I16=8,16,0,0,864,32420,0,0,1347,78123,0,0,445,10033,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,242:9:0 0,33,255:11:0 0,12,95:4:0 +17 1691 . T 0 . DP=22;I16=7,14,0,0,734,27150,0,0,1167,67323,0,0,421,9525,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,225:9:0 0,30,242:10:0 0,6,57:2:0 +17 1692 . G 0 . DP=22;I16=7,13,0,0,678,24110,0,0,1107,63723,0,0,400,9176,0,0;QS=3,0;MQSB=0.999215;MQ0F=0 PL:DP:DV 0,24,218:8:0 0,30,218:10:0 0,6,61:2:0 +17 1693 . T 0 . DP=24;I16=10,13,0,0,795,28363,0,0,1318,77282,0,0,444,10422,0,0;QS=3,0;MQSB=0.995682;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,30,235:10:0 0,12,104:4:0 +17 1694 . T 0 . DP=24;I16=10,13,0,0,771,26775,0,0,1318,77282,0,0,448,10602,0,0;QS=3,0;MQSB=0.995682;MQ0F=0 PL:DP:DV 0,27,221:9:0 0,30,232:10:0 0,12,114:4:0 +17 1695 . C 0 . DP=24;I16=10,14,0,0,811,28517,0,0,1347,78123,0,0,454,10806,0,0;QS=3,0;MQSB=0.98469;MQ0F=0 PL:DP:DV 0,27,227:9:0 0,33,239:11:0 0,12,121:4:0 +17 1696 . T 0 . DP=23;I16=10,13,0,0,825,30819,0,0,1287,74523,0,0,455,10869,0,0;QS=3,0;MQSB=0.976718;MQ0F=0 PL:DP:DV 0,24,219:8:0 0,33,255:11:0 0,12,108:4:0 +17 1697 . G 0 . DP=23;I16=10,13,0,0,767,26757,0,0,1287,74523,0,0,455,10897,0,0;QS=3,0;MQSB=0.976718;MQ0F=0 PL:DP:DV 0,24,208:8:0 0,33,246:11:0 0,12,112:4:0 +17 1698 . C A, 0 . DP=21;I16=10,10,0,1,726,27088,27,729,1169,69241,29,841,451,10903,6,36;QS=2.91148,0.0885246,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.99938;BQB=1;MQ0F=0 PL:DP:DV 0,24,229,24,229,229:8:0 0,0,190,24,193,207:9:1 0,12,111,12,111,111:4:0 +17 1699 . T 0 . DP=21;I16=9,10,0,0,698,25826,0,0,1078,62882,0,0,408,9692,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,21,203:7:0 0,24,219:8:0 0,12,115:4:0 +17 1700 . G 0 . DP=20;I16=9,10,0,0,696,25850,0,0,1078,62882,0,0,409,9705,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,21,216:7:0 0,24,215:8:0 0,12,110:4:0 +17 1701 . T 0 . DP=20;I16=9,11,0,0,711,25539,0,0,1138,66482,0,0,435,10353,0,0;QS=3,0;MQSB=0.997118;MQ0F=0 PL:DP:DV 0,24,207:8:0 0,24,210:8:0 0,12,125:4:0 +17 1702 . T 0 . DP=20;I16=8,11,0,0,671,24367,0,0,1078,62882,0,0,410,9712,0,0;QS=3,0;MQSB=0.992359;MQ0F=0 PL:DP:DV 0,24,214:8:0 0,21,193:7:0 0,12,115:4:0 +17 1703 . T 0 . DP=20;I16=9,10,0,0,648,22696,0,0,1078,62882,0,0,410,9708,0,0;QS=3,0;MQSB=0.999167;MQ0F=0 PL:DP:DV 0,21,197:7:0 0,24,195:8:0 0,12,114:4:0 +17 1704 . T 0 . DP=20;I16=10,10,0,0,711,25771,0,0,1169,69241,0,0,435,10341,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,24,208:8:0 0,21,208:7:0 0,15,128:5:0 +17 1705 . C 0 . DP=20;I16=10,10,0,0,744,28388,0,0,1169,69241,0,0,436,10312,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,24,232:8:0 0,21,213:7:0 0,15,120:5:0 +17 1706 . T 0 . DP=20;I16=10,10,0,0,775,30329,0,0,1169,69241,0,0,436,10246,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,21,219:7:0 0,15,145:5:0 +17 1707 . C 0 . DP=21;I16=9,11,0,0,724,26998,0,0,1169,69241,0,0,410,9518,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,27,235:9:0 0,18,180:6:0 0,15,134:5:0 +17 1708 . T 0 . DP=21;I16=9,12,0,0,740,27282,0,0,1229,72841,0,0,410,9430,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,30,229:10:0 0,18,187:6:0 0,15,132:5:0 +17 1709 . A 0 . DP=21;I16=9,11,0,0,675,23509,0,0,1169,69241,0,0,386,8734,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,27,210:9:0 0,18,166:6:0 0,15,131:5:0 +17 1710 . C 0 . DP=22;I16=9,13,0,0,755,26817,0,0,1289,76441,0,0,412,9306,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,33,236:11:0 0,18,181:6:0 0,15,128:5:0 +17 1711 . C 0 . DP=22;I16=9,13,0,0,786,28790,0,0,1289,76441,0,0,413,9223,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,33,250:11:0 0,18,169:6:0 0,15,138:5:0 +17 1712 . A 0 . DP=22;I16=9,13,0,0,824,31342,0,0,1289,76441,0,0,414,9162,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,33,252:11:0 0,18,198:6:0 0,15,136:5:0 +17 1713 . G 0 . DP=23;I16=8,14,0,0,823,31285,0,0,1289,76441,0,0,405,8993,0,0;QS=3,0;MQSB=0.892142;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,189:6:0 0,12,118:4:0 +17 1714 . A 0 . DP=23;I16=9,13,0,0,763,27439,0,0,1289,76441,0,0,402,8818,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,36,234:12:0 0,18,190:6:0 0,12,101:4:0 +17 1715 . A 0 . DP=23;I16=9,14,0,0,900,35416,0,0,1349,80041,0,0,414,8878,0,0;QS=3,0;MQSB=0.907354;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,206:6:0 0,15,145:5:0 +17 1716 . G 0 . DP=23;I16=9,14,0,0,844,31500,0,0,1349,80041,0,0,414,8822,0,0;QS=3,0;MQSB=0.907354;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,188:6:0 0,15,129:5:0 +17 1717 . T 0 . DP=24;I16=9,15,0,0,854,30878,0,0,1409,83641,0,0,414,8794,0,0;QS=3,0;MQSB=0.904837;MQ0F=0 PL:DP:DV 0,39,253:13:0 0,18,185:6:0 0,15,122:5:0 +17 1718 . G 0 . DP=24;I16=9,14,0,0,806,29332,0,0,1349,80041,0,0,390,8170,0,0;QS=3,0;MQSB=0.907354;MQ0F=0 PL:DP:DV 0,36,249:12:0 0,18,188:6:0 0,15,124:5:0 +17 1719 . C 0 . DP=26;I16=11,14,0,0,857,30717,0,0,1469,87241,0,0,407,8675,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,173:6:0 0,12,98:4:0 +17 1720 . C 0 . DP=26;I16=11,14,0,0,898,33274,0,0,1469,87241,0,0,409,8645,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,166:6:0 0,12,99:4:0 +17 1721 . C 0 . DP=26;I16=10,14,0,0,846,30642,0,0,1409,83641,0,0,388,8258,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,187:6:0 0,12,119:4:0 +17 1722 . T 0 . DP=25;I16=11,13,0,0,876,33054,0,0,1409,83641,0,0,406,8540,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,174:5:0 0,15,123:5:0 +17 1723 . T 0 . DP=25;I16=11,14,0,0,835,28861,0,0,1469,87241,0,0,420,8728,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,167:5:0 0,15,130:5:0 +17 1724 . C 0 . DP=25;I16=11,14,0,0,903,33735,0,0,1469,87241,0,0,422,8800,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,164:5:0 0,15,139:5:0 +17 1725 . C G, 0 . DP=25;I16=11,13,0,1,835,29699,25,625,1409,83641,60,3600,406,8576,18,324;QS=2.95164,0.0483559,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.929204;BQB=1;MQ0F=0 PL:DP:DV 0,20,255,42,255,255:15:1 0,15,153,15,153,153:5:0 0,15,132,15,132,132:5:0 +17 1726 . C 0 . DP=25;I16=11,14,0,0,932,35588,0,0,1469,87241,0,0,426,9028,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,165:5:0 0,15,122:5:0 +17 1727 . T 0 . DP=25;I16=10,14,0,0,862,32080,0,0,1409,83641,0,0,404,8556,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,167:5:0 0,12,120:4:0 +17 1728 . C 0 . DP=25;I16=11,14,0,0,915,33845,0,0,1469,87241,0,0,429,9173,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,156:5:0 0,15,144:5:0 +17 1729 . C 0 . DP=25;I16=10,14,0,0,919,35797,0,0,1409,83641,0,0,406,8668,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,142:5:0 0,12,128:4:0 +17 1730 . T 0 . DP=24;I16=10,14,0,0,849,30711,0,0,1409,83641,0,0,433,9393,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,138:4:0 0,15,148:5:0 +17 1731 . C 0 . DP=24;I16=10,14,0,0,907,34875,0,0,1409,83641,0,0,434,9472,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,123:4:0 0,15,140:5:0 +17 1732 . A 0 . DP=24;I16=11,13,0,0,816,28582,0,0,1409,83641,0,0,436,9580,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,123:4:0 0,15,143:5:0 +17 1733 . C 0 . DP=25;I16=12,13,0,0,869,31451,0,0,1469,87241,0,0,438,9666,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,116:4:0 0,15,136:5:0 +17 1734 . C 0 . DP=25;I16=12,13,0,0,926,35482,0,0,1469,87241,0,0,440,9730,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,122:4:0 0,15,141:5:0 +17 1735 . T 0 . DP=26;I16=13,13,0,0,935,35169,0,0,1529,90841,0,0,442,9822,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,112:4:0 0,15,148:5:0 +17 1736 . G 0 . DP=25;I16=11,11,0,0,829,31469,0,0,1289,76441,0,0,380,8416,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,72:2:0 0,12,118:4:0 +17 1737 . A 0 . DP=25;I16=12,12,0,0,842,30606,0,0,1409,83641,0,0,422,9312,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,76:2:0 0,15,131:5:0 +17 1738 . C 0 . DP=24;I16=12,12,0,0,835,30251,0,0,1409,83641,0,0,450,10010,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,78:3:0 0,15,130:5:0 +17 1739 . C 0 . DP=23;I16=10,12,0,0,831,32123,0,0,1289,76441,0,0,428,9432,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,55:2:0 0,12,135:4:0 +17 1740 . A 0 . DP=23;I16=11,12,0,0,774,27126,0,0,1349,80041,0,0,456,10126,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,56:2:0 0,15,139:5:0 +17 1741 . C 0 . DP=23;I16=11,12,0,0,850,32314,0,0,1349,80041,0,0,459,10217,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,70:2:0 0,15,136:5:0 +17 1742 . T 0 . DP=23;I16=11,12,0,0,866,33204,0,0,1349,80041,0,0,462,10330,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,72:2:0 0,15,144:5:0 +17 1743 . C 0 . DP=23;I16=11,12,0,0,894,35176,0,0,1349,80041,0,0,464,10414,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,74:2:0 0,15,138:5:0 +17 1744 . T 0 . DP=23;I16=11,11,0,0,857,33579,0,0,1289,76441,0,0,459,10469,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,80:2:0 0,15,156:5:0 +17 1745 . G 0 . DP=23;I16=11,12,0,0,882,34572,0,0,1349,80041,0,0,464,10442,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,78:2:0 0,15,142:5:0 +17 1746 . G 0 . DP=24;I16=12,11,0,0,836,31102,0,0,1349,80041,0,0,456,10312,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,69:2:0 0,18,151:6:0 +17 1747 . G 0 . DP=24;I16=12,11,0,0,839,31729,0,0,1349,80041,0,0,455,10239,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,75:2:0 0,18,154:6:0 +17 1748 . G 0 . DP=24;I16=11,12,0,0,843,31857,0,0,1349,80041,0,0,434,9664,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,42:1:0 0,18,154:6:0 +17 1749 . A 0 . DP=25;I16=13,11,0,0,864,31748,0,0,1409,83641,0,0,451,10063,0,0;QS=3,0;MQSB=0.950498;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,72:2:0 0,21,172:7:0 +17 1750 . A 0 . DP=25;I16=13,12,0,0,905,33667,0,0,1469,87241,0,0,451,10013,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,56:2:0 0,21,187:7:0 +17 1751 . A 0 . DP=25;I16=13,12,0,0,908,33658,0,0,1469,87241,0,0,449,9987,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,67:2:0 0,21,183:7:0 +17 1752 . T 0 . DP=23;I16=12,11,0,0,838,31088,0,0,1380,82800,0,0,449,9987,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,71:2:0 0,18,170:6:0 +17 1753 . C 0 . DP=23;I16=12,11,0,0,869,33595,0,0,1380,82800,0,0,448,9960,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,77:2:0 0,18,163:6:0 +17 1754 . C 0 . DP=23;I16=11,11,0,0,830,31628,0,0,1320,79200,0,0,431,9699,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,3,42:1:0 0,18,163:6:0 +17 1755 . C 0 . DP=23;I16=12,11,0,0,856,33082,0,0,1380,82800,0,0,446,9972,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,61:2:0 0,18,165:6:0 +17 1756 . T 0 . DP=22;I16=11,11,0,0,858,33720,0,0,1320,79200,0,0,445,9961,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,77:2:0 0,18,179:6:0 +17 1757 . C 0 . DP=22;I16=11,11,0,0,869,34651,0,0,1320,79200,0,0,444,9972,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,78:2:0 0,18,176:6:0 +17 1758 . A 0 . DP=22;I16=11,11,0,0,865,34205,0,0,1320,79200,0,0,442,9954,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,81:2:0 0,18,177:6:0 +17 1759 . G 0 . DP=22;I16=11,11,0,0,833,31965,0,0,1320,79200,0,0,439,9905,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,77:2:0 0,18,159:6:0 +17 1760 . C 0 . DP=22;I16=11,11,0,0,849,33441,0,0,1320,79200,0,0,436,9874,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,79:2:0 0,18,159:6:0 +17 1761 . A 0 . DP=22;I16=11,11,0,0,730,25766,0,0,1320,79200,0,0,432,9810,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,75:2:0 0,18,153:6:0 +17 1762 . C 0 . DP=21;I16=11,10,0,0,767,28667,0,0,1260,75600,0,0,429,9761,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,76:2:0 0,18,160:6:0 +17 1763 . C 0 . DP=21;I16=11,10,0,0,789,30115,0,0,1260,75600,0,0,426,9726,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,72:2:0 0,18,162:6:0 +17 1764 . C 0 . DP=21;I16=11,10,0,0,821,32443,0,0,1260,75600,0,0,423,9705,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,72:2:0 0,18,167:6:0 +17 1765 . T 0 . DP=21;I16=11,10,0,0,814,31746,0,0,1260,75600,0,0,420,9698,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,83:2:0 0,18,179:6:0 +17 1766 . C 0 . DP=21;I16=11,10,0,0,796,30564,0,0,1260,75600,0,0,417,9705,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,71:2:0 0,18,162:6:0 +17 1767 . C 0 . DP=21;I16=11,10,0,0,779,29559,0,0,1260,75600,0,0,414,9726,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,73:2:0 0,18,163:6:0 +17 1768 . C 0 . DP=21;I16=11,10,0,0,798,30670,0,0,1260,75600,0,0,411,9761,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,68:2:0 0,18,160:6:0 +17 1769 . T 0 . DP=21;I16=11,10,0,0,819,32179,0,0,1260,75600,0,0,406,9712,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,77:2:0 0,18,184:6:0 +17 1770 . G 0 . DP=19;I16=11,8,0,0,699,26453,0,0,1140,68400,0,0,403,9679,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,68:2:0 0,18,158:6:0 +17 1771 . A 0 . DP=18;I16=10,8,0,0,707,27853,0,0,1080,64800,0,0,401,9659,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,42:1:0 0,18,177:6:0 +17 1772 . G 0 . DP=18;I16=10,8,0,0,669,25513,0,0,1080,64800,0,0,398,9600,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,38:1:0 0,18,159:6:0 +17 1773 . C 0 . DP=17;I16=10,7,0,0,675,26897,0,0,1020,61200,0,0,396,9550,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,3,39:1:0 0,18,172:6:0 +17 1774 . A 0 . DP=17;I16=10,7,0,0,653,25153,0,0,1020,61200,0,0,394,9508,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,3,39:1:0 0,18,172:6:0 +17 1775 . T 0 . DP=17;I16=10,7,0,0,605,22253,0,0,1020,61200,0,0,391,9423,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,3,38:1:0 0,18,156:6:0 +17 1776 . A 0 . DP=17;I16=10,7,0,0,610,22124,0,0,1020,61200,0,0,388,9344,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,254:10:0 0,3,35:1:0 0,18,166:6:0 +17 1777 . C 0 . DP=18;I16=11,7,0,0,661,24975,0,0,1080,64800,0,0,385,9271,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,35:1:0 0,18,158:6:0 +17 1778 . C 0 . DP=18;I16=11,7,0,0,680,25970,0,0,1080,64800,0,0,383,9205,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,31:1:0 0,18,172:6:0 +17 1779 . C 0 . DP=18;I16=11,7,0,0,703,27663,0,0,1080,64800,0,0,381,9147,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,34:1:0 0,18,174:6:0 +17 1780 . T 0 . DP=18;I16=11,7,0,0,672,26000,0,0,1080,64800,0,0,378,9048,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,33:1:0 0,18,177:6:0 +17 1781 . A 0 . DP=19;I16=10,6,0,0,579,21377,0,0,960,57600,0,0,328,7804,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,0,0:0:0 0,15,160:5:0 +17 1782 . C 0 . DP=20;I16=11,9,0,0,715,26603,0,0,1200,72000,0,0,382,8892,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,47:2:0 0,18,156:6:0 +17 1783 . T 0 . DP=20;I16=11,9,0,0,755,29057,0,0,1200,72000,0,0,381,8743,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,68:2:0 0,18,184:6:0 +17 1784 . C 0 . DP=20;I16=10,9,0,0,723,28017,0,0,1140,68400,0,0,360,8212,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,62:2:0 0,15,151:5:0 +17 1785 . T 0 . DP=20;I16=10,10,0,0,766,29878,0,0,1200,72000,0,0,359,8089,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,66:2:0 0,15,168:5:0 +17 1786 . G 0 . DP=22;I16=11,11,0,0,841,32323,0,0,1320,79200,0,0,359,7985,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,68:2:0 0,15,158:5:0 +17 1787 . G 0 . DP=22;I16=11,11,0,0,806,30294,0,0,1320,79200,0,0,361,7903,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,68:2:0 0,15,148:5:0 +17 1788 . C 0 . DP=22;I16=11,11,0,0,858,33674,0,0,1320,79200,0,0,362,7796,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,67:2:0 0,15,158:5:0 +17 1789 . A 0 . DP=23;I16=11,12,0,0,797,28705,0,0,1380,82800,0,0,363,7715,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,69:2:0 0,15,157:5:0 +17 1790 . C 0 . DP=23;I16=11,12,0,0,852,31816,0,0,1380,82800,0,0,365,7661,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,63:2:0 0,15,153:5:0 +17 1791 . A 0 . DP=23;I16=11,12,0,0,830,30484,0,0,1380,82800,0,0,367,7635,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,61:2:0 0,15,155:5:0 +17 1792 . A 0 . DP=23;I16=11,12,0,0,862,32760,0,0,1380,82800,0,0,368,7588,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,67:2:0 0,15,161:5:0 +17 1793 . G 0 . DP=23;I16=11,12,0,0,813,29603,0,0,1380,82800,0,0,369,7571,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,61:2:0 0,15,126:5:0 +17 1794 . C 0 . DP=21;I16=9,12,0,0,736,26472,0,0,1260,75600,0,0,370,7484,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,48:2:0 0,9,96:3:0 +17 1795 . C 0 . DP=21;I16=9,12,0,0,763,28807,0,0,1260,75600,0,0,371,7427,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,45:2:0 0,9,100:3:0 +17 1796 . C 0 . DP=21;I16=9,12,0,0,782,29718,0,0,1260,75600,0,0,372,7400,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,52:2:0 0,9,102:3:0 +17 1797 . A 0 . DP=21;I16=9,12,0,0,704,25190,0,0,1260,75600,0,0,373,7403,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,59:2:0 0,9,92:3:0 +17 1798 . C 0 . DP=21;I16=9,12,0,0,759,28119,0,0,1260,75600,0,0,374,7436,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,49:2:0 0,9,99:3:0 +17 1799 . C 0 . DP=22;I16=9,13,0,0,796,29520,0,0,1320,79200,0,0,375,7499,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,56:2:0 0,12,131:4:0 +17 1800 . C 0 . DP=22;I16=9,13,0,0,866,34352,0,0,1320,79200,0,0,376,7542,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,63:2:0 0,12,138:4:0 +17 1801 . T 0 . DP=22;I16=9,13,0,0,838,32282,0,0,1320,79200,0,0,377,7615,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,63:2:0 0,12,150:4:0 +17 1802 . G 0 . DP=22;I16=9,13,0,0,844,32894,0,0,1320,79200,0,0,378,7718,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,60:2:0 0,12,137:4:0 +17 1803 . C 0 . DP=22;I16=9,13,0,0,837,32691,0,0,1320,79200,0,0,377,7751,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,60:2:0 0,12,143:4:0 +17 1804 . A 0 . DP=23;I16=9,14,0,0,793,28517,0,0,1380,82800,0,0,376,7814,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,54:2:0 0,12,144:4:0 +17 1805 . A 0 . DP=23;I16=9,14,0,0,810,29148,0,0,1380,82800,0,0,376,7908,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,67:2:0 0,12,138:4:0 +17 1806 . A 0 . DP=23;I16=9,14,0,0,816,29932,0,0,1380,82800,0,0,376,8034,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,61:2:0 0,12,139:4:0 +17 1807 . G 0 . DP=22;I16=9,13,0,0,837,32299,0,0,1320,79200,0,0,375,8091,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,67:2:0 0,12,142:4:0 +17 1808 . C 0 . DP=21;I16=9,11,0,0,705,25519,0,0,1200,72000,0,0,354,7716,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,53:2:0 0,12,140:4:0 +17 1809 . C 0 . DP=22;I16=10,12,0,0,789,29123,0,0,1320,79200,0,0,371,8091,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,55:2:0 0,12,143:4:0 +17 1810 . C 0 . DP=21;I16=10,11,0,0,754,27902,0,0,1260,75600,0,0,370,8084,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,51:2:0 0,12,145:4:0 +17 1811 . C 0 . DP=22;I16=11,11,0,0,837,32353,0,0,1320,79200,0,0,368,8056,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,61:2:0 0,12,146:4:0 +17 1812 . T 0 . DP=22;I16=11,11,0,0,830,31782,0,0,1320,79200,0,0,365,7955,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,60:2:0 0,12,151:4:0 +17 1813 . G 0 . DP=21;I16=11,10,0,0,789,29971,0,0,1260,75600,0,0,363,7879,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,63:2:0 0,12,135:4:0 +17 1814 . A 0 . DP=21;I16=11,10,0,0,780,29356,0,0,1260,75600,0,0,361,7827,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,63:2:0 0,12,148:4:0 +17 1815 . G 0 . DP=21;I16=11,10,0,0,742,27064,0,0,1260,75600,0,0,358,7748,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,56:2:0 0,12,135:4:0 +17 1816 . G 0 . DP=21;I16=11,10,0,0,702,24670,0,0,1260,75600,0,0,355,7691,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,49:2:0 0,12,124:4:0 +17 1817 . C 0 . DP=20;I16=11,9,0,0,701,25263,0,0,1200,72000,0,0,353,7655,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,58:2:0 0,12,134:4:0 +17 1818 . C 0 . DP=20;I16=11,8,0,0,665,23987,0,0,1140,68400,0,0,326,7014,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,53:2:0 0,12,132:4:0 +17 1819 . C 0 . DP=18;I16=9,9,0,0,580,20092,0,0,1080,64800,0,0,351,7641,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,38:2:0 0,12,124:4:0 +17 1820 . G 0 . DP=18;I16=9,9,0,0,589,19883,0,0,1080,64800,0,0,351,7659,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,58:2:0 0,12,117:4:0 +17 1821 . C 0 . DP=18;I16=9,9,0,0,619,22131,0,0,1080,64800,0,0,351,7693,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,60:2:0 0,12,131:4:0 +17 1822 . C 0 . DP=18;I16=9,9,0,0,655,24177,0,0,1080,64800,0,0,350,7694,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,58:2:0 0,12,131:4:0 +17 1823 . C 0 . DP=19;I16=10,9,0,0,703,26765,0,0,1140,68400,0,0,349,7713,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,62:2:0 0,12,138:4:0 +17 1824 . T 0 . DP=19;I16=10,9,0,0,714,27628,0,0,1140,68400,0,0,349,7751,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,69:2:0 0,12,149:4:0 +17 1825 . G 0 . DP=19;I16=10,9,0,0,682,24804,0,0,1140,68400,0,0,347,7709,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,61:2:0 0,12,129:4:0 +17 1826 . T 0 . DP=19;I16=10,9,0,0,643,22525,0,0,1140,68400,0,0,345,7687,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,62:2:0 0,12,141:4:0 +17 1827 . G 0 . DP=19;I16=10,9,0,0,722,27844,0,0,1140,68400,0,0,343,7685,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,66:2:0 0,12,134:4:0 +17 1828 . G 0 . DP=18;I16=10,8,0,0,619,21719,0,0,1080,64800,0,0,342,7702,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,61:2:0 0,9,100:3:0 +17 1829 . C 0 . DP=19;I16=9,9,0,0,576,19228,0,0,1080,64800,0,0,323,7413,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,59:3:0 0,9,103:3:0 +17 1830 . G 0 . DP=19;I16=9,9,0,0,582,19586,0,0,1080,64800,0,0,321,7379,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,82:3:0 0,9,80:3:0 +17 1831 . T 0 . DP=20;I16=10,8,0,0,605,21015,0,0,1080,64800,0,0,294,6736,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,106:4:0 0,9,101:3:0 +17 1832 . C 0 . DP=19;I16=9,9,0,0,675,25747,0,0,1080,64800,0,0,319,7359,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,110:4:0 0,9,105:3:0 +17 1833 . T 0 . DP=18;I16=8,8,0,0,565,20733,0,0,960,57600,0,0,295,6747,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,9,105:3:0 0,9,106:3:0 +17 1834 . C 0 . DP=19;I16=9,9,0,0,654,24424,0,0,1037,61489,0,0,321,7399,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,104:4:0 0,9,107:3:0 +17 1835 . T 0 . DP=18;I16=9,9,0,0,641,23505,0,0,1037,61489,0,0,347,7965,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,123:4:0 0,9,115:3:0 +17 1836 . C 0 . DP=18;I16=9,9,0,0,657,24427,0,0,1037,61489,0,0,350,8016,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,127:4:0 0,9,108:3:0 +17 1837 . C 0 . DP=18;I16=9,9,0,0,586,20044,0,0,1037,61489,0,0,352,8030,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,233:11:0 0,12,114:4:0 0,9,108:3:0 +17 1838 . C 0 . DP=18;I16=9,9,0,0,655,24607,0,0,1037,61489,0,0,354,8056,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,120:4:0 0,9,107:3:0 +17 1839 . T 0 . DP=18;I16=9,7,0,0,557,20543,0,0,917,54289,0,0,321,7369,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,30,231:10:0 0,9,103:3:0 0,9,119:3:0 +17 1840 . C 0 . DP=18;I16=9,9,0,0,637,23295,0,0,1037,61489,0,0,358,8144,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,116:4:0 0,9,109:3:0 +17 1841 . C 0 . DP=18;I16=9,9,0,0,622,22458,0,0,1037,61489,0,0,360,8206,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,252:11:0 0,12,121:4:0 0,9,108:3:0 +17 1842 . C 0 . DP=18;I16=9,9,0,0,672,26064,0,0,1037,61489,0,0,362,8280,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,124:4:0 0,9,108:3:0 +17 1843 . T 0 . DP=18;I16=9,9,0,0,630,22746,0,0,1037,61489,0,0,364,8366,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,243:11:0 0,12,131:4:0 0,9,107:3:0 +17 1844 . T 0 . DP=18;I16=9,9,0,0,618,21618,0,0,1037,61489,0,0,366,8464,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,240:11:0 0,12,137:4:0 0,9,98:3:0 +17 1845 . G 0 . DP=18;I16=9,9,0,0,644,23976,0,0,1037,61489,0,0,368,8574,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,138:4:0 0,9,82:3:0 +17 1846 . C 0 . DP=18;I16=9,9,0,0,687,26809,0,0,1037,61489,0,0,370,8696,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,129:4:0 0,9,100:3:0 +17 1847 . T 0 . DP=18;I16=9,9,0,0,675,25529,0,0,1037,61489,0,0,373,8829,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,132:4:0 0,6,76:2:0 +17 1848 . G 0 . DP=18;I16=9,9,0,0,597,20845,0,0,1037,61489,0,0,377,8973,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,118:4:0 0,6,64:2:0 +17 1849 . T 0 . DP=20;I16=9,10,0,0,614,20770,0,0,1097,65089,0,0,380,9078,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,119:4:0 0,6,71:2:0 +17 1850 . C 0 . DP=19;I16=8,11,0,0,684,25154,0,0,1097,65089,0,0,409,9769,0,0;QS=3,0;MQSB=0.902014;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,120:4:0 0,3,37:1:0 +17 1851 . A 0 . DP=20;I16=9,11,0,0,738,27838,0,0,1157,68689,0,0,413,9847,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,143:4:0 0,3,41:1:0 +17 1852 . G 0 . DP=19;I16=8,11,0,0,639,22239,0,0,1097,65089,0,0,392,9264,0,0;QS=3,0;MQSB=0.902014;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,117:4:0 0,3,36:1:0 +17 1853 . G 0 . DP=20;I16=9,11,0,0,627,20873,0,0,1157,68689,0,0,396,9322,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,127:5:0 0,3,38:1:0 +17 1854 . A 0 . DP=22;I16=10,11,0,0,674,22428,0,0,1217,72289,0,0,401,9397,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,145:5:0 0,3,38:1:0 +17 1855 . C 0 . DP=22;I16=10,12,0,0,771,27949,0,0,1277,75889,0,0,407,9441,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,132:5:0 0,3,37:1:0 +17 1856 . A 0 . DP=22;I16=10,12,0,0,806,30230,0,0,1277,75889,0,0,412,9456,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,146:5:0 0,3,41:1:0 +17 1857 . G 0 . DP=22;I16=10,12,0,0,699,23919,0,0,1277,75889,0,0,416,9442,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,134:5:0 0,3,35:1:0 +17 1858 . T 0 . DP=23;I16=10,13,0,0,773,26797,0,0,1337,79489,0,0,419,9399,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,148:5:0 0,3,37:1:0 +17 1859 . G 0 . DP=23;I16=10,13,0,0,798,28594,0,0,1337,79489,0,0,423,9379,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,146:5:0 0,3,36:1:0 +17 1860 . G 0 . DP=23;I16=10,13,0,0,726,23842,0,0,1337,79489,0,0,425,9283,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,126:5:0 0,3,33:1:0 +17 1861 . T 0 . DP=23;I16=10,13,0,0,741,24793,0,0,1337,79489,0,0,425,9113,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,143:5:0 0,3,39:1:0 +17 1862 . C 0 . DP=23;I16=10,12,0,0,738,25732,0,0,1277,75889,0,0,403,8487,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,135:5:0 0,3,34:1:0 +17 1863 . C 0 . DP=24;I16=10,13,0,0,804,29186,0,0,1337,79489,0,0,400,8232,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,133:5:0 0,3,36:1:0 +17 1864 . T 0 . DP=24;I16=11,11,0,0,766,27572,0,0,1277,75889,0,0,392,8174,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,125:4:0 0,3,37:1:0 +17 1865 . G 0 . DP=24;I16=11,13,0,0,860,31394,0,0,1397,83089,0,0,425,8621,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,154:5:0 0,3,38:1:0 +17 1866 . G 0 . DP=24;I16=11,13,0,0,795,27503,0,0,1397,83089,0,0,425,8551,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,152:5:0 0,3,36:1:0 +17 1867 . C 0 . DP=24;I16=9,13,0,0,726,24886,0,0,1320,79200,0,0,375,7263,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,122:5:0 0,3,38:1:0 +17 1868 . C 0 . DP=24;I16=11,12,0,0,857,32293,0,0,1337,79489,0,0,411,8311,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,118:4:0 0,3,41:1:0 +17 1869 . A T, 0 . DP=24;I16=6,9,5,4,531,19001,268,8660,857,50689,540,32400,273,5667,152,2866;QS=1.4724,1.5276,0;VDB=0.928022;SGB=-11.9537;RPB=0.984127;MQB=0.96464;MQSB=0.931547;BQB=0.359155;MQ0F=0 PL:DP:DV 115,0,224,148,245,255:18:7 16,0,104,28,107,128:5:1 42,3,0,42,3,42:1:1 +17 1870 . C 0 . DP=25;I16=11,13,0,0,804,27826,0,0,1397,83089,0,0,425,8591,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,127:5:0 0,3,36:1:0 +17 1871 . C 0 . DP=25;I16=11,14,0,0,761,24187,0,0,1457,86689,0,0,428,8690,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,128:6:0 0,3,29:1:0 +17 1872 . G 0 . DP=25;I16=10,14,0,0,763,25437,0,0,1397,83089,0,0,425,8803,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,132:6:0 0,3,43:1:0 +17 1873 . G 0 . DP=26;I16=11,15,0,0,790,25548,0,0,1517,90289,0,0,429,8931,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,151:7:0 0,3,43:1:0 +17 1874 . G 0 . DP=27;I16=11,16,0,0,861,29013,0,0,1577,93889,0,0,430,9076,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,172:8:0 0,3,43:1:0 +17 1875 . G 0 . DP=26;I16=11,15,0,0,800,26216,0,0,1517,90289,0,0,431,9155,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,168:7:0 0,3,42:1:0 +17 1876 . C 0 . DP=26;I16=10,15,0,0,894,32714,0,0,1457,86689,0,0,432,9268,0,0;QS=3,0;MQSB=0.9171;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,171:7:0 0,3,41:1:0 +17 1877 . T 0 . DP=25;I16=9,15,0,0,848,30804,0,0,1397,83089,0,0,409,8787,0,0;QS=3,0;MQSB=0.904837;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,163:6:0 0,3,42:1:0 +17 1878 . C 0 . DP=25;I16=10,15,0,0,906,33478,0,0,1457,86689,0,0,434,9488,0,0;QS=3,0;MQSB=0.9171;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,166:7:0 0,3,40:1:0 +17 1879 . A 0 . DP=26;I16=10,16,0,0,911,32761,0,0,1517,90289,0,0,433,9543,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,191:8:0 0,3,40:1:0 +17 1880 . C 0 . DP=26;I16=10,16,0,0,790,24876,0,0,1517,90289,0,0,431,9527,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,152:8:0 0,3,31:1:0 +17 1881 . G 0 . DP=27;I16=10,15,0,0,782,25352,0,0,1500,90000,0,0,380,8288,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,144:7:0 0,3,42:1:0 +17 1882 . G 0 . DP=28;I16=12,15,0,0,937,33215,0,0,1577,93889,0,0,406,8952,0,0;QS=3,0;MQSB=0.935229;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,164:7:0 0,3,42:1:0 +17 1883 . A 0 . DP=29;I16=14,15,0,0,998,35394,0,0,1697,101089,0,0,434,9646,0,0;QS=3,0;MQSB=0.947838;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,24,180:8:0 0,3,43:1:0 +17 1884 . G 0 . DP=29;I16=14,15,0,0,1036,37926,0,0,1697,101089,0,0,437,9647,0,0;QS=3,0;MQSB=0.947838;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,24,202:8:0 0,3,42:1:0 +17 1885 . C 0 . DP=28;I16=14,13,0,0,925,32305,0,0,1577,93889,0,0,430,9560,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,182:7:0 0,3,42:1:0 +17 1886 . C 0 . DP=26;I16=13,13,0,0,826,27194,0,0,1517,90289,0,0,447,9745,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,166:8:0 0,3,32:1:0 +17 1887 . G 0 . DP=26;I16=12,13,0,0,798,26554,0,0,1500,90000,0,0,428,9212,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,185:8:0 0,3,40:1:0 +17 1888 . C 0 . DP=26;I16=13,13,0,0,901,32343,0,0,1517,90289,0,0,459,9957,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,178:8:0 0,3,39:1:0 +17 1889 . C 0 . DP=25;I16=13,11,0,0,825,29127,0,0,1397,83089,0,0,444,9612,0,0;QS=3,0;MQSB=0.950498;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,187:7:0 0,3,37:1:0 +17 1890 . C 0 . DP=25;I16=13,12,0,0,913,34029,0,0,1457,86689,0,0,471,10173,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,198:8:0 0,3,40:1:0 +17 1891 . T 0 . DP=25;I16=13,12,0,0,912,34028,0,0,1457,86689,0,0,477,10317,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,212:8:0 0,3,39:1:0 +17 1892 . G 0 . DP=25;I16=12,12,0,0,885,33149,0,0,1397,83089,0,0,458,9860,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,166:7:0 0,3,37:1:0 +17 1893 . T 0 . DP=26;I16=14,12,0,0,920,33494,0,0,1517,90289,0,0,489,10677,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,205:8:0 0,6,72:2:0 +17 1894 . G 0 . DP=26;I16=14,12,0,0,934,35048,0,0,1517,90289,0,0,495,10843,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,188:8:0 0,6,75:2:0 +17 1895 . C 0 . DP=26;I16=13,12,0,0,882,31980,0,0,1500,90000,0,0,476,10408,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,180:8:0 0,6,73:2:0 +17 1896 . C 0 . DP=26;I16=14,11,0,0,827,28179,0,0,1457,86689,0,0,482,10622,0,0;QS=3,0;MQSB=0.955682;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,154:7:0 0,6,72:2:0 +17 1897 . G 0 . DP=26;I16=13,11,0,0,763,25169,0,0,1397,83089,0,0,486,10856,0,0;QS=3,0;MQSB=0.950498;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,164:7:0 0,3,27:1:0 +17 1898 . T 0 . DP=27;I16=14,11,0,0,846,29526,0,0,1500,90000,0,0,492,11072,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,187:8:0 0,6,62:2:0 +17 1899 . G 0 . DP=27;I16=14,11,0,0,875,32007,0,0,1500,90000,0,0,497,11213,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,188:8:0 0,6,61:2:0 +17 1900 . T 0 . DP=26;I16=14,11,0,0,850,29882,0,0,1500,90000,0,0,501,11329,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,185:8:0 0,6,69:2:0 +17 1901 . A 0 . DP=27;I16=15,10,0,0,842,29298,0,0,1457,86689,0,0,505,11469,0,0;QS=3,0;MQSB=0.962269;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,190:7:0 0,6,68:2:0 +17 1902 . C 0 . DP=27;I16=15,12,0,0,912,31970,0,0,1577,93889,0,0,537,12267,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,184:8:0 0,6,60:2:0 +17 1903 . C 0 . DP=27;I16=15,12,0,0,959,34645,0,0,1577,93889,0,0,542,12462,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,201:8:0 0,6,63:2:0 +17 1904 . T 0 . DP=27;I16=16,11,0,0,1017,38757,0,0,1577,93889,0,0,548,12682,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,221:8:0 0,6,77:2:0 +17 1905 . C 0 . DP=27;I16=16,11,0,0,985,36561,0,0,1577,93889,0,0,553,12827,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,211:8:0 0,6,69:2:0 +17 1906 . T 0 . DP=27;I16=16,11,0,0,1018,39242,0,0,1577,93889,0,0,558,12998,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,207:8:0 0,6,75:2:0 +17 1907 . G 0 . DP=27;I16=15,11,0,0,935,34679,0,0,1517,90289,0,0,535,12419,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,187:7:0 0,6,68:2:0 +17 1908 . A 0 . DP=28;I16=16,12,0,0,1023,38221,0,0,1637,97489,0,0,561,13063,0,0;QS=3,0;MQSB=0.96195;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,215:8:0 0,6,67:2:0 +17 1909 . G 0 . DP=27;I16=15,12,0,0,1002,38398,0,0,1577,93889,0,0,561,12953,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,206:8:0 0,6,73:2:0 +17 1910 . C 0 . DP=27;I16=14,10,0,0,855,31251,0,0,1440,86400,0,0,502,11588,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,179:7:0 0,6,71:2:0 +17 1911 . C 0 . DP=27;I16=15,12,0,0,967,35429,0,0,1577,93889,0,0,561,12793,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,206:8:0 0,6,71:2:0 +17 1912 . C 0 . DP=27;I16=15,12,0,0,1024,39272,0,0,1577,93889,0,0,561,12743,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,217:8:0 0,6,73:2:0 +17 1913 . T 0 . DP=27;I16=15,12,0,0,1028,39768,0,0,1577,93889,0,0,561,12713,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,228:8:0 0,6,77:2:0 +17 1914 . C 0 . DP=27;I16=15,12,0,0,1010,38762,0,0,1577,93889,0,0,561,12703,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,221:8:0 0,6,75:2:0 +17 1915 . T C, 0 . DP=27;I16=14,12,1,0,974,37184,16,256,1560,93600,17,289,543,12389,18,324;QS=2.97351,0.0264901,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.958048;BQB=1;MQ0F=0 PL:DP:DV 0,34,255,48,255,255:17:1 0,24,231,24,231,231:8:0 0,6,60,6,60,60:2:0 +17 1916 . G T, 0 . DP=27;I16=14,12,1,0,991,38291,15,225,1560,93600,17,289,544,12454,17,289;QS=2.97581,0.0241935,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.958048;BQB=1;MQ0F=0 PL:DP:DV 0,35,255,48,255,255:17:1 0,24,226,24,226,226:8:0 0,6,69,6,69,69:2:0 +17 1917 . C 0 . DP=27;I16=15,12,0,0,1030,39740,0,0,1577,93889,0,0,561,12793,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,214:8:0 0,6,73:2:0 +17 1918 . A 0 . DP=27;I16=15,11,0,0,963,36201,0,0,1517,90289,0,0,542,12502,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,217:8:0 0,6,72:2:0 +17 1919 . C 0 . DP=27;I16=15,12,0,0,987,36651,0,0,1577,93889,0,0,560,12902,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,214:8:0 0,6,72:2:0 +17 1920 . A T, 0 . DP=29;I16=15,12,0,1,1007,38337,14,196,1546,91130,60,3600,538,12518,21,441;QS=2.97647,0.0235294,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.999735;BQB=1;MQ0F=0 PL:DP:DV 0,36,255,48,255,255:17:1 0,24,225,24,225,225:8:0 0,9,101,9,101,101:3:0 +17 1921 . G 0 . DP=30;I16=15,14,0,0,1059,39815,0,0,1666,98330,0,0,542,12474,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,182:7:0 0,12,132:4:0 +17 1922 . T 0 . DP=29;I16=14,14,0,0,1013,37513,0,0,1649,98041,0,0,532,12418,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,197:7:0 0,12,134:4:0 +17 1923 . G 0 . DP=28;I16=14,14,0,0,1034,38974,0,0,1606,94730,0,0,545,12629,0,0;QS=3,0;MQSB=0.999736;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,188:7:0 0,12,126:4:0 +17 1924 . C 0 . DP=27;I16=13,13,0,0,965,36587,0,0,1486,87530,0,0,521,12017,0,0;QS=3,0;MQSB=0.999671;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,183:7:0 0,12,116:4:0 +17 1925 . C 0 . DP=27;I16=14,13,0,0,987,37021,0,0,1546,91130,0,0,546,12626,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,187:7:0 0,12,124:4:0 +17 1926 . T 0 . DP=27;I16=14,13,0,0,1031,40057,0,0,1546,91130,0,0,545,12581,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,197:7:0 0,12,141:4:0 +17 1927 . T 0 . DP=27;I16=13,13,0,0,959,35773,0,0,1529,90841,0,0,538,12522,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,191:7:0 0,12,133:4:0 +17 1928 . C 0 . DP=27;I16=13,13,0,0,986,38264,0,0,1529,90841,0,0,538,12532,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,189:7:0 0,12,125:4:0 +17 1929 . T 0 . DP=27;I16=13,13,0,0,990,38630,0,0,1529,90841,0,0,538,12562,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,189:7:0 0,12,139:4:0 +17 1930 . G 0 . DP=26;I16=13,11,0,0,905,34865,0,0,1409,83641,0,0,521,12271,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,179:6:0 0,9,99:3:0 +17 1931 . C 0 . DP=27;I16=15,12,0,0,967,36293,0,0,1546,91130,0,0,540,12578,0,0;QS=3,0;MQSB=0.99881;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,165:6:0 0,12,121:4:0 +17 1932 . T 0 . DP=27;I16=14,13,0,0,998,38154,0,0,1546,91130,0,0,541,12605,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,143:5:0 0,15,146:5:0 +17 1933 . T 0 . DP=27;I16=14,13,0,0,962,35344,0,0,1546,91130,0,0,542,12602,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,142:5:0 0,15,158:5:0 +17 1934 . G 0 . DP=27;I16=13,13,0,0,987,38219,0,0,1529,90841,0,0,543,12569,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,134:5:0 0,15,143:5:0 +17 1935 . C 0 . DP=27;I16=14,12,0,0,963,36627,0,0,1529,90841,0,0,520,11930,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,162:6:0 0,15,154:5:0 +17 1936 . C 0 . DP=27;I16=14,13,0,0,1018,39406,0,0,1589,94441,0,0,547,12561,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,177:6:0 0,15,159:5:0 +17 1937 . T 0 . DP=27;I16=14,13,0,0,1036,40636,0,0,1589,94441,0,0,547,12489,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,182:6:0 0,15,170:5:0 +17 1938 . G 0 . DP=27;I16=14,13,0,0,1001,38377,0,0,1589,94441,0,0,546,12392,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,166:6:0 0,15,155:5:0 +17 1939 . T 0 . DP=27;I16=14,12,0,0,964,36430,0,0,1560,93600,0,0,525,11909,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,167:6:0 0,12,144:4:0 +17 1940 . G 0 . DP=27;I16=14,13,0,0,1003,37937,0,0,1589,94441,0,0,542,12172,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,159:6:0 0,15,155:5:0 +17 1941 . G 0 . DP=27;I16=14,13,0,0,1004,38072,0,0,1589,94441,0,0,540,12098,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,176:6:0 0,15,156:5:0 +17 1942 . C 0 . DP=27;I16=14,12,0,0,996,38790,0,0,1560,93600,0,0,516,11564,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,174:6:0 0,12,140:4:0 +17 1943 . T 0 . DP=27;I16=14,13,0,0,1044,40952,0,0,1589,94441,0,0,536,12022,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,184:6:0 0,15,167:5:0 +17 1944 . T 0 . DP=27;I16=14,13,0,0,987,37237,0,0,1589,94441,0,0,533,11971,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,175:6:0 0,15,170:5:0 +17 1945 . T 0 . DP=27;I16=14,13,0,0,993,37067,0,0,1589,94441,0,0,530,11946,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,174:6:0 0,15,171:5:0 +17 1946 . G 0 . DP=27;I16=14,13,0,0,1013,38617,0,0,1589,94441,0,0,526,11896,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,162:6:0 0,15,162:5:0 +17 1947 . A 0 . DP=26;I16=13,13,0,0,950,35522,0,0,1529,90841,0,0,522,11818,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,167:6:0 0,15,160:5:0 +17 1948 . G C, 0 . DP=27;I16=14,12,0,1,966,36912,16,256,1560,93600,29,841,493,11135,25,625;QS=2.90361,0.0963855,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.94394;BQB=1;MQ0F=0 PL:DP:DV 0,45,255,45,255,255:15:0 0,21,190,21,190,190:7:0 1,0,123,13,126,132:5:1 +17 1949 . A 0 . DP=26;I16=14,11,0,0,871,31325,0,0,1469,87241,0,0,490,11048,0,0;QS=3,0;MQSB=0.929204;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,174:7:0 0,15,155:5:0 +17 1950 . A 0 . DP=27;I16=14,13,0,0,1007,38049,0,0,1589,94441,0,0,511,11559,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,205:7:0 0,18,176:6:0 +17 1951 . G 0 . DP=27;I16=14,13,0,0,960,35536,0,0,1589,94441,0,0,509,11469,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,180:7:0 0,18,181:6:0 +17 1952 . A 0 . DP=27;I16=14,12,0,0,924,33366,0,0,1529,90841,0,0,483,10779,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,184:7:0 0,18,182:6:0 +17 1953 . A 0 . DP=28;I16=15,12,0,0,925,32719,0,0,1589,94441,0,0,482,10740,0,0;QS=3,0;MQSB=0.935229;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,189:7:0 0,18,168:6:0 +17 1954 . A C, 0 . DP=29;I16=14,13,0,1,929,33219,18,324,1620,97200,29,841,475,10679,25,625;QS=2.90217,0.0978261,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.949591;BQB=1;MQ0F=0 PL:DP:DV 0,45,255,45,255,255:15:0 0,21,198,21,198,198:7:0 0,0,130,15,133,141:6:1 +17 1955 . C 0 . DP=29;I16=14,12,0,0,961,36067,0,0,1560,93600,0,0,451,10035,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,206:7:0 0,15,165:5:0 +17 1956 . C 0 . DP=29;I16=14,13,0,0,964,35402,0,0,1620,97200,0,0,475,10573,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,196:7:0 0,15,164:5:0 +17 1957 . C 0 . DP=29;I16=14,13,0,0,980,36212,0,0,1620,97200,0,0,472,10420,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,183:7:0 0,15,167:5:0 +17 1958 . C 0 . DP=29;I16=15,13,0,0,1003,37293,0,0,1649,98041,0,0,493,10825,0,0;QS=3,0;MQSB=0.942064;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,191:7:0 0,18,190:6:0 +17 1959 . T 0 . DP=29;I16=16,13,0,0,1112,43258,0,0,1709,101641,0,0,491,10593,0,0;QS=3,0;MQSB=0.940317;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,213:7:0 0,18,193:6:0 +17 1960 . T 0 . DP=30;I16=17,13,0,0,1053,37939,0,0,1769,105241,0,0,485,10339,0,0;QS=3,0;MQSB=0.938685;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,196:7:0 0,18,186:6:0 +17 1961 . C 0 . DP=30;I16=17,13,0,0,1101,41737,0,0,1769,105241,0,0,480,10122,0,0;QS=3,0;MQSB=0.938685;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,195:7:0 0,18,183:6:0 +17 1962 . T 0 . DP=29;I16=17,12,0,0,1134,44582,0,0,1709,101641,0,0,477,9941,0,0;QS=3,0;MQSB=0.931617;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,208:7:0 0,18,198:6:0 +17 1963 . G 0 . DP=28;I16=16,12,0,0,1066,41050,0,0,1649,98041,0,0,476,9794,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,192:7:0 0,18,188:6:0 +17 1964 . G 0 . DP=28;I16=16,12,0,0,970,34764,0,0,1649,98041,0,0,475,9681,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,178:7:0 0,18,169:6:0 +17 1965 . T 0 . DP=29;I16=16,12,0,0,964,34772,0,0,1649,98041,0,0,449,8977,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,196:7:0 0,18,171:6:0 +17 1966 . T 0 . DP=29;I16=16,13,0,0,1029,37027,0,0,1709,101641,0,0,474,9558,0,0;QS=3,0;MQSB=0.940317;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,191:7:0 0,18,181:6:0 +17 1967 . A 0 . DP=29;I16=16,13,0,0,1030,37234,0,0,1709,101641,0,0,474,9550,0,0;QS=3,0;MQSB=0.940317;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,187:7:0 0,18,182:6:0 +17 1968 . T 0 . DP=29;I16=16,13,0,0,1075,40173,0,0,1709,101641,0,0,474,9578,0,0;QS=3,0;MQSB=0.940317;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,195:7:0 0,18,190:6:0 +17 1969 . A 0 . DP=28;I16=16,12,0,0,992,35828,0,0,1649,98041,0,0,474,9592,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,175:6:0 0,18,186:6:0 +17 1970 . C 0 . DP=28;I16=16,12,0,0,1015,37503,0,0,1649,98041,0,0,474,9642,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,170:6:0 0,18,180:6:0 +17 1971 . A 0 . DP=29;I16=16,13,0,0,1073,40273,0,0,1709,101641,0,0,474,9728,0,0;QS=3,0;MQSB=0.940317;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,178:6:0 0,21,206:7:0 +17 1972 . T 0 . DP=30;I16=16,14,0,0,1068,38978,0,0,1769,105241,0,0,475,9851,0,0;QS=3,0;MQSB=0.946202;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,176:6:0 0,21,203:7:0 +17 1973 . A 0 . DP=30;I16=16,13,0,0,1046,38070,0,0,1740,104400,0,0,452,9388,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,172:6:0 0,18,196:6:0 +17 1974 . A 0 . DP=29;I16=16,13,0,0,1086,41474,0,0,1709,101641,0,0,477,10065,0,0;QS=3,0;MQSB=0.940317;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,157:5:0 0,21,214:7:0 +17 1975 . G 0 . DP=28;I16=16,12,0,0,1067,41171,0,0,1649,98041,0,0,478,10156,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,133:4:0 0,21,195:7:0 +17 1976 . A 0 . DP=28;I16=16,12,0,0,981,34839,0,0,1649,98041,0,0,478,10234,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,125:4:0 0,21,199:7:0 +17 1977 . C 0 . DP=28;I16=16,12,0,0,1009,37471,0,0,1649,98041,0,0,477,10297,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,132:4:0 0,21,194:7:0 +17 1978 . A 0 . DP=28;I16=16,12,0,0,1082,42132,0,0,1649,98041,0,0,476,10394,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,144:4:0 0,21,220:7:0 +17 1979 . G 0 . DP=28;I16=16,11,0,0,1019,38927,0,0,1589,94441,0,0,454,10064,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,122:4:0 0,21,208:7:0 +17 1980 . C 0 . DP=27;I16=16,10,0,0,932,34456,0,0,1529,90841,0,0,452,10114,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,107:3:0 0,21,197:7:0 +17 1981 . C 0 . DP=28;I16=16,12,0,0,998,36510,0,0,1649,98041,0,0,469,10479,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,101:3:0 0,24,219:8:0 +17 1982 . A 0 . DP=29;I16=16,12,0,0,1035,38815,0,0,1649,98041,0,0,472,10548,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,110:3:0 0,27,254:9:0 +17 1983 . G 0 . DP=28;I16=16,12,0,0,1048,40322,0,0,1649,98041,0,0,477,10599,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,96:3:0 0,27,249:9:0 +17 1984 . A 0 . DP=27;I16=16,11,0,0,1024,39232,0,0,1589,94441,0,0,482,10632,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,70:2:0 0,27,255:9:0 +17 1985 . G 0 . DP=27;I16=16,11,0,0,1009,38449,0,0,1589,94441,0,0,487,10695,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,66:2:0 0,27,231:9:0 +17 1986 . A 0 . DP=27;I16=16,10,0,0,926,33696,0,0,1560,93600,0,0,466,10112,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,76:2:0 0,24,223:8:0 +17 1987 . A 0 . DP=28;I16=17,11,0,0,1034,39088,0,0,1649,98041,0,0,495,10807,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,78:2:0 0,27,247:9:0 +17 1988 . G 0 . DP=28;I16=17,11,0,0,1050,39980,0,0,1649,98041,0,0,499,10855,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,63:2:0 0,27,239:9:0 +17 1989 . G 0 . DP=28;I16=17,10,0,0,994,37610,0,0,1589,94441,0,0,493,10801,0,0;QS=3,0;MQSB=0.912952;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,73:2:0 0,27,237:9:0 +17 1990 . G T, 0 . DP=28;I16=17,9,0,1,965,36359,33,1089,1560,93600,29,841,472,10250,25,625;QS=2.90675,0.0932476,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.912952;BQB=1;MQ0F=0 PL:DP:DV 0,48,255,48,255,255:16:0 0,6,71,6,71,71:2:0 2,0,195,26,198,215:9:1 +17 1991 . A 0 . DP=28;I16=17,11,0,0,1017,38203,0,0,1649,98041,0,0,507,10975,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,60:2:0 0,27,250:9:0 +17 1992 . G 0 . DP=28;I16=17,11,0,0,1028,38852,0,0,1649,98041,0,0,509,11039,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,62:2:0 0,27,231:9:0 +17 1993 . T 0 . DP=28;I16=17,11,0,0,1015,37325,0,0,1649,98041,0,0,511,11131,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,59:2:0 0,27,243:9:0 +17 1994 . T 0 . DP=27;I16=16,11,0,0,942,33698,0,0,1589,94441,0,0,514,11250,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,54:2:0 0,24,216:8:0 +17 1995 . G 0 . DP=28;I16=16,11,0,0,960,35432,0,0,1620,97200,0,0,492,10770,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,66:2:0 0,21,188:7:0 +17 1996 . C 0 . DP=29;I16=17,12,0,0,1022,37426,0,0,1709,101641,0,0,519,11469,0,0;QS=3,0;MQSB=0.931617;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,64:2:0 0,24,192:8:0 +17 1997 . C 0 . DP=29;I16=17,11,0,0,934,32858,0,0,1649,98041,0,0,520,11524,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,70:2:0 0,24,193:8:0 +17 1998 . C 0 . DP=29;I16=17,12,0,0,1027,37843,0,0,1709,101641,0,0,522,11562,0,0;QS=3,0;MQSB=0.931617;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,69:2:0 0,24,222:8:0 +17 1999 . A 0 . DP=28;I16=17,11,0,0,1073,41493,0,0,1649,98041,0,0,525,11627,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,72:2:0 0,21,206:7:0 +17 2000 . G 0 . DP=28;I16=16,11,0,0,1036,40576,0,0,1589,94441,0,0,511,11395,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,72:2:0 0,18,168:6:0 +17 2001 . G 0 . DP=28;I16=15,11,0,0,955,35661,0,0,1529,90841,0,0,489,10853,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,62:2:0 0,18,172:6:0 +17 2002 . G 0 . DP=28;I16=17,10,0,0,907,32227,0,0,1620,97200,0,0,519,11663,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,53:2:0 0,18,163:6:0 +17 2003 . T 0 . DP=28;I16=17,11,0,0,920,31866,0,0,1649,98041,0,0,541,12163,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,49:2:0 0,21,190:7:0 +17 2004 . G 0 . DP=27;I16=16,10,0,0,970,36928,0,0,1560,93600,0,0,530,12110,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,57:2:0 0,18,178:6:0 +17 2005 . G 0 . DP=27;I16=16,10,0,0,868,30936,0,0,1560,93600,0,0,536,12370,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,59:2:0 0,18,153:6:0 +17 2006 . C 0 . DP=27;I16=16,10,0,0,968,37046,0,0,1560,93600,0,0,541,12605,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,73:2:0 0,18,166:6:0 +17 2007 . A 0 . DP=27;I16=16,11,0,0,1000,37396,0,0,1589,94441,0,0,556,12882,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,76:2:0 0,21,193:7:0 +17 2008 . C 0 . DP=26;I16=16,10,0,0,964,36892,0,0,1529,90841,0,0,555,12833,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,73:2:0 0,21,183:7:0 +17 2009 . A 0 . DP=26;I16=16,10,0,0,997,38955,0,0,1529,90841,0,0,554,12802,0,0;QS=3,0;MQSB=0.914947;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,74:2:0 0,21,210:7:0 +17 2010 . G 0 . DP=26;I16=16,9,0,0,936,36208,0,0,1500,90000,0,0,542,12640,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,73:2:0 0,18,169:6:0 +17 2011 . C 0 . DP=26;I16=16,9,0,0,966,37960,0,0,1500,90000,0,0,541,12617,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,74:2:0 0,18,175:6:0 +17 2012 . A 0 . DP=27;I16=16,11,0,0,956,35018,0,0,1589,94441,0,0,548,12676,0,0;QS=3,0;MQSB=0.925036;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,74:2:0 0,21,189:7:0 +17 2013 . C 0 . DP=27;I16=15,10,0,0,876,31370,0,0,1500,90000,0,0,514,11950,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,69:2:0 0,18,160:6:0 +17 2014 . G 0 . DP=27;I16=17,10,0,0,903,31239,0,0,1589,94441,0,0,545,12591,0,0;QS=3,0;MQSB=0.912952;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,80:3:0 0,18,160:6:0 +17 2015 . T 0 . DP=27;I16=17,10,0,0,999,37507,0,0,1589,94441,0,0,545,12577,0,0;QS=3,0;MQSB=0.912952;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,95:3:0 0,18,178:6:0 +17 2016 . T 0 . DP=27;I16=17,10,0,0,971,35649,0,0,1589,94441,0,0,545,12583,0,0;QS=3,0;MQSB=0.912952;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,93:3:0 0,18,178:6:0 +17 2017 . G 0 . DP=28;I16=17,11,0,0,1013,37849,0,0,1649,98041,0,0,545,12609,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,9,91:3:0 0,18,172:6:0 +17 2018 . C 0 . DP=28;I16=17,11,0,0,1060,41414,0,0,1649,98041,0,0,546,12656,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,9,97:3:0 0,18,169:6:0 +17 2019 . T 0 . DP=28;I16=17,11,0,0,1083,42253,0,0,1649,98041,0,0,547,12725,0,0;QS=3,0;MQSB=0.923174;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,9,106:3:0 0,18,187:6:0 +17 2020 . G 0 . DP=29;I16=18,11,0,0,1095,42063,0,0,1678,98882,0,0,548,12816,0,0;QS=3,0;MQSB=0.987702;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,9,85:3:0 0,18,175:6:0 +17 2021 . C 0 . DP=29;I16=18,11,0,0,1081,41535,0,0,1709,101641,0,0,551,12877,0,0;QS=3,0;MQSB=0.969907;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,97:3:0 0,15,167:5:0 +17 2022 . C 0 . DP=30;I16=19,11,0,0,1115,42003,0,0,1769,105241,0,0,555,12907,0,0;QS=3,0;MQSB=0.972375;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,92:3:0 0,18,177:6:0 +17 2023 . A 0 . DP=30;I16=19,10,0,0,1063,39991,0,0,1709,101641,0,0,549,12837,0,0;QS=3,0;MQSB=0.974027;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,9,96:3:0 0,18,186:6:0 +17 2024 . G 0 . DP=32;I16=20,12,0,0,1168,43872,0,0,1889,112441,0,0,564,12982,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,92:3:0 0,24,203:8:0 +17 2025 . T 0 . DP=32;I16=20,12,0,0,1150,42122,0,0,1889,112441,0,0,569,12981,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,87:3:0 0,24,226:8:0 +17 2026 . T 0 . DP=32;I16=20,12,0,0,1130,40724,0,0,1889,112441,0,0,572,12908,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,94:3:0 0,24,208:8:0 +17 2027 . A 0 . DP=32;I16=19,12,0,0,1121,40871,0,0,1829,108841,0,0,550,12240,0,0;QS=3,0;MQSB=0.970829;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,84:3:0 0,21,207:7:0 +17 2028 . C 0 . DP=32;I16=20,12,0,0,1242,48548,0,0,1889,112441,0,0,577,12803,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,94:3:0 0,24,228:8:0 +17 2029 . T 0 . DP=32;I16=20,12,0,0,1229,47605,0,0,1889,112441,0,0,578,12724,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,102:3:0 0,24,236:8:0 +17 2030 . G 0 . DP=32;I16=20,12,0,0,1222,47140,0,0,1889,112441,0,0,579,12679,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,93:3:0 0,24,216:8:0 +17 2031 . C 0 . DP=31;I16=19,12,0,0,1150,43656,0,0,1829,108841,0,0,581,12667,0,0;QS=3,0;MQSB=0.970829;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,9,96:3:0 0,24,204:8:0 +17 2032 . C 0 . DP=31;I16=19,12,0,0,1157,44035,0,0,1829,108841,0,0,583,12687,0,0;QS=3,0;MQSB=0.970829;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,9,90:3:0 0,24,210:8:0 +17 2033 . A 0 . DP=30;I16=19,11,0,0,1091,40223,0,0,1769,105241,0,0,585,12689,0,0;QS=3,0;MQSB=0.972375;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,9,93:3:0 0,21,203:7:0 +17 2034 . T 0 . DP=30;I16=19,11,0,0,1104,41498,0,0,1769,105241,0,0,587,12723,0,0;QS=3,0;MQSB=0.972375;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,9,91:3:0 0,21,208:7:0 +17 2035 . T 0 . DP=29;I16=18,11,0,0,1084,41024,0,0,1709,101641,0,0,589,12739,0,0;QS=3,0;MQSB=0.969907;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,69:2:0 0,21,211:7:0 +17 2036 . T 0 . DP=29;I16=18,11,0,0,1080,40612,0,0,1709,101641,0,0,591,12787,0,0;QS=3,0;MQSB=0.969907;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,67:2:0 0,21,216:7:0 +17 2037 . T 0 . DP=29;I16=18,11,0,0,1082,40956,0,0,1709,101641,0,0,592,12818,0,0;QS=3,0;MQSB=0.969907;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,69:2:0 0,21,217:7:0 +17 2038 . C 0 . DP=29;I16=18,11,0,0,1117,43573,0,0,1709,101641,0,0,592,12832,0,0;QS=3,0;MQSB=0.969907;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,69:2:0 0,21,211:7:0 +17 2039 . A 0 . DP=29;I16=18,11,0,0,1067,39581,0,0,1709,101641,0,0,592,12878,0,0;QS=3,0;MQSB=0.969907;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,72:2:0 0,21,212:7:0 +17 2040 . C 0 . DP=29;I16=18,11,0,0,1077,40469,0,0,1709,101641,0,0,590,12856,0,0;QS=3,0;MQSB=0.969907;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,69:2:0 0,21,196:7:0 +17 2041 . G A, 0 . DP=31;I16=6,5,12,7,389,14023,721,28149,660,39600,1109,65641,235,5607,353,7259;QS=0.917304,2.0827,0;VDB=0.816435;SGB=-4.18892;RPB=0.88473;MQB=0.972375;MQSB=0.968257;BQB=0.311275;MQ0F=0 PL:DP:DV 229,0,212,255,245,255:21:11 32,0,24,35,27,59:2:1 223,21,0,223,21,223:7:7 +17 2042 . G 0 . DP=32;I16=18,14,0,0,1189,45617,0,0,1889,112441,0,0,588,12910,0,0;QS=3,0;MQSB=0.965264;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,9,86:3:0 0,21,206:7:0 +17 2043 . G 0 . DP=32;I16=17,14,0,0,1115,41585,0,0,1829,108841,0,0,581,12891,0,0;QS=3,0;MQSB=0.962133;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,9,90:3:0 0,21,197:7:0 +17 2044 . C 0 . DP=32;I16=18,14,0,0,1213,47029,0,0,1889,112441,0,0,588,13006,0,0;QS=3,0;MQSB=0.965264;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,9,85:3:0 0,21,207:7:0 +17 2045 . A 0 . DP=32;I16=18,14,0,0,1181,44527,0,0,1889,112441,0,0,588,13108,0,0;QS=3,0;MQSB=0.965264;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,9,83:3:0 0,21,213:7:0 +17 2046 . T 0 . DP=32;I16=18,14,0,0,1197,45135,0,0,1889,112441,0,0,587,13195,0,0;QS=3,0;MQSB=0.965264;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,9,103:3:0 0,21,216:7:0 +17 2047 . G 0 . DP=34;I16=17,16,0,0,1248,47798,0,0,1949,116041,0,0,557,12491,0,0;QS=3,0;MQSB=0.959328;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,9,88:3:0 0,18,195:6:0 +17 2048 . A 0 . DP=34;I16=18,16,0,0,1230,45184,0,0,2009,119641,0,0,578,13022,0,0;QS=3,0;MQSB=0.962621;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,9,87:3:0 0,21,206:7:0 +17 2049 . A 0 . DP=33;I16=17,16,0,0,1207,44567,0,0,1949,116041,0,0,575,12963,0,0;QS=3,0;MQSB=0.959328;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,6,74:2:0 0,21,208:7:0 +17 2050 . A 0 . DP=33;I16=16,16,0,0,1169,43313,0,0,1889,112441,0,0,545,12211,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,6,77:2:0 0,18,188:6:0 +17 2051 . T 0 . DP=31;I16=16,15,0,0,1134,42164,0,0,1829,108841,0,0,567,12737,0,0;QS=3,0;MQSB=0.957006;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,6,69:2:0 0,18,170:6:0 +17 2052 . G 0 . DP=31;I16=16,15,0,0,1180,45546,0,0,1829,108841,0,0,564,12664,0,0;QS=3,0;MQSB=0.957006;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,6,74:2:0 0,18,175:6:0 +17 2053 . G T, 0 . DP=31;I16=15,15,0,1,1126,42672,23,529,1769,105241,60,3600,537,11991,25,625;QS=2.97307,0.0269321,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.951229;BQB=1;MQ0F=0 PL:DP:DV 0,46,255,66,255,255:23:1 0,6,71,6,71,71:2:0 0,18,180,18,180,180:6:0 +17 2054 . A 0 . DP=30;I16=15,15,0,0,1123,43027,0,0,1769,105241,0,0,562,12592,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,6,78:2:0 0,18,171:6:0 +17 2055 . G 0 . DP=30;I16=15,15,0,0,1156,45206,0,0,1769,105241,0,0,562,12592,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,6,66:2:0 0,18,168:6:0 +17 2056 . A 0 . DP=30;I16=15,15,0,0,1124,42416,0,0,1769,105241,0,0,560,12518,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,6,71:2:0 0,18,179:6:0 +17 2057 . T 0 . DP=30;I16=15,15,0,0,1094,40082,0,0,1769,105241,0,0,556,12374,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,6,72:2:0 0,18,178:6:0 +17 2058 . A 0 . DP=29;I16=14,15,0,0,1035,37517,0,0,1709,101641,0,0,552,12212,0,0;QS=3,0;MQSB=0.947838;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,6,57:2:0 0,18,179:6:0 +17 2059 . A 0 . DP=29;I16=14,15,0,0,1063,39615,0,0,1709,101641,0,0,548,12082,0,0;QS=3,0;MQSB=0.947838;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,6,66:2:0 0,18,188:6:0 +17 2060 . C 0 . DP=28;I16=12,15,0,0,1015,39057,0,0,1589,94441,0,0,523,11499,0,0;QS=3,0;MQSB=0.935229;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,62:2:0 0,15,143:5:0 +17 2061 . A 0 . DP=27;I16=12,14,0,0,950,35084,0,0,1529,90841,0,0,501,11073,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,3,41:1:0 0,15,163:5:0 +17 2062 . A 0 . DP=26;I16=11,15,0,0,973,37349,0,0,1529,90841,0,0,519,11425,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,57:2:0 0,15,164:5:0 +17 2063 . C 0 . DP=26;I16=11,15,0,0,1017,40149,0,0,1529,90841,0,0,517,11405,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,74:2:0 0,15,158:5:0 +17 2064 . A 0 . DP=26;I16=11,15,0,0,1002,38980,0,0,1529,90841,0,0,515,11413,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,75:2:0 0,15,164:5:0 +17 2065 . G 0 . DP=26;I16=12,14,0,0,1030,41232,0,0,1529,90841,0,0,514,11448,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,78:2:0 0,18,167:6:0 +17 2066 . G 0 . DP=26;I16=12,14,0,0,973,37055,0,0,1529,90841,0,0,514,11510,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,75:2:0 0,18,152:6:0 +17 2067 . A 0 . DP=26;I16=12,14,0,0,1005,39095,0,0,1529,90841,0,0,512,11498,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,69:2:0 0,18,187:6:0 +17 2068 . G 0 . DP=26;I16=12,14,0,0,993,39005,0,0,1529,90841,0,0,509,11459,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,53:2:0 0,18,167:6:0 +17 2069 . C 0 . DP=26;I16=12,14,0,0,873,29879,0,0,1529,90841,0,0,506,11442,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,59:2:0 0,18,156:6:0 +17 2070 . G 0 . DP=27;I16=13,14,0,0,932,33090,0,0,1589,94441,0,0,502,11398,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,62:2:0 0,18,145:6:0 +17 2071 . A 0 . DP=27;I16=13,14,0,0,946,33884,0,0,1589,94441,0,0,498,11330,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,53:2:0 0,18,177:6:0 +17 2072 . C 0 . DP=25;I16=13,12,0,0,897,32897,0,0,1469,87241,0,0,496,11288,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,59:2:0 0,15,128:5:0 +17 2073 . C 0 . DP=26;I16=14,12,0,0,874,30184,0,0,1529,90841,0,0,492,11168,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,53:2:0 0,15,133:5:0 +17 2074 . G 0 . DP=26;I16=13,12,0,0,835,29219,0,0,1469,87241,0,0,463,10395,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,67:2:0 0,12,83:4:0 +17 2075 . C 0 . DP=27;I16=15,12,0,0,989,37027,0,0,1589,94441,0,0,484,10896,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,69:2:0 0,15,115:5:0 +17 2076 . A 0 . DP=27;I16=14,12,0,0,929,33551,0,0,1529,90841,0,0,470,10676,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,76:2:0 0,12,114:4:0 +17 2077 . C 0 . DP=27;I16=15,12,0,0,990,37252,0,0,1589,94441,0,0,478,10724,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,65:2:0 0,15,125:5:0 +17 2078 . A 0 . DP=27;I16=15,12,0,0,1023,39089,0,0,1589,94441,0,0,475,10677,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,6,72:2:0 0,15,148:5:0 +17 2079 . G 0 . DP=28;I16=15,13,0,0,1042,39694,0,0,1649,98041,0,0,471,10605,0,0;QS=3,0;MQSB=0.956162;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,6,72:2:0 0,15,133:5:0 +17 2080 . G 0 . DP=28;I16=14,13,0,0,968,35328,0,0,1589,94441,0,0,453,10333,0,0;QS=3,0;MQSB=0.951472;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,6,67:2:0 0,12,108:4:0 +17 2081 . C 0 . DP=26;I16=14,12,0,0,937,35303,0,0,1529,90841,0,0,467,10535,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,63:2:0 0,15,110:5:0 +17 2082 . T 0 . DP=24;I16=12,12,0,0,901,34287,0,0,1409,83641,0,0,468,10532,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,71:2:0 0,12,112:4:0 +17 2083 . G 0 . DP=24;I16=12,12,0,0,887,33597,0,0,1409,83641,0,0,469,10547,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,68:2:0 0,12,113:4:0 +17 2084 . C 0 . DP=25;I16=13,12,0,0,938,35868,0,0,1469,87241,0,0,470,10580,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,61:2:0 0,12,115:4:0 +17 2085 . T 0 . DP=25;I16=13,12,0,0,932,35282,0,0,1469,87241,0,0,472,10632,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,64:2:0 0,12,130:4:0 +17 2086 . G 0 . DP=25;I16=13,12,0,0,932,35400,0,0,1469,87241,0,0,474,10704,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,6,61:2:0 0,12,129:4:0 +17 2087 . A 0 . DP=24;I16=12,12,0,0,903,34391,0,0,1409,83641,0,0,476,10746,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,66:2:0 0,12,126:4:0 +17 2088 . G 0 . DP=24;I16=12,12,0,0,880,33116,0,0,1409,83641,0,0,478,10808,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,70:2:0 0,12,121:4:0 +17 2089 . C 0 . DP=25;I16=13,12,0,0,817,27419,0,0,1469,87241,0,0,480,10890,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,64:2:0 0,15,138:5:0 +17 2090 . G 0 . DP=25;I16=12,12,0,0,802,27940,0,0,1409,83641,0,0,457,10319,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,63:2:0 0,12,99:4:0 +17 2091 . C 0 . DP=25;I16=12,12,0,0,800,27346,0,0,1440,86400,0,0,458,10346,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,61:2:0 0,15,125:5:0 +17 2092 . G 0 . DP=26;I16=13,12,0,0,838,29188,0,0,1469,87241,0,0,461,10487,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,64:2:0 0,18,133:6:0 +17 2093 . T G, 0 . DP=26;I16=13,12,1,0,905,33415,17,289,1500,90000,29,841,459,10371,25,625;QS=2.97424,0.0257576,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.953497;BQB=1;MQ0F=0 PL:DP:DV 0,36,255,51,255,255:18:1 0,6,67,6,67,67:2:0 0,18,153,18,153,153:6:0 +17 2094 . C 0 . DP=26;I16=14,12,0,0,949,35501,0,0,1529,90841,0,0,485,11047,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,69:2:0 0,18,142:6:0 +17 2095 . A 0 . DP=25;I16=14,11,0,0,879,31219,0,0,1469,87241,0,0,487,11123,0,0;QS=3,0;MQSB=0.955682;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,72:2:0 0,18,154:6:0 +17 2096 . C 0 . DP=24;I16=13,11,0,0,878,32734,0,0,1409,83641,0,0,487,11073,0,0;QS=3,0;MQSB=0.950498;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,65:2:0 0,18,161:6:0 +17 2097 . A 0 . DP=24;I16=13,11,0,0,849,30671,0,0,1409,83641,0,0,487,11047,0,0;QS=3,0;MQSB=0.950498;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,56:2:0 0,18,172:6:0 +17 2098 . C 0 . DP=24;I16=13,11,0,0,781,26113,0,0,1409,83641,0,0,486,10996,0,0;QS=3,0;MQSB=0.950498;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,58:2:0 0,18,139:6:0 +17 2099 . G 0 . DP=23;I16=12,10,0,0,719,25109,0,0,1289,76441,0,0,460,10294,0,0;QS=3,0;MQSB=0.947103;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,3,24:1:0 0,18,129:6:0 +17 2100 . C 0 . DP=25;I16=13,11,0,0,873,32759,0,0,1409,83641,0,0,457,10141,0,0;QS=3,0;MQSB=0.950498;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,87:3:0 0,18,160:6:0 +17 2101 . A 0 . DP=25;I16=12,12,0,0,907,34671,0,0,1440,86400,0,0,455,9965,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,135:4:0 0,18,161:6:0 +17 2102 . G 0 . DP=25;I16=13,12,0,0,930,35596,0,0,1469,87241,0,0,478,10442,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,118:4:0 0,18,151:6:0 +17 2103 . C 0 . DP=25;I16=11,12,0,0,842,31630,0,0,1380,82800,0,0,432,9336,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,106:4:0 0,15,146:5:0 +17 2104 . C 0 . DP=24;I16=12,12,0,0,869,32463,0,0,1409,83641,0,0,454,9810,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,126:4:0 0,15,147:5:0 +17 2105 . A 0 . DP=25;I16=11,12,0,0,836,30696,0,0,1380,82800,0,0,429,9201,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,138:4:0 0,15,130:5:0 +17 2106 . T 0 . DP=25;I16=12,13,0,0,897,33087,0,0,1469,87241,0,0,473,10211,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,129:4:0 0,15,146:5:0 +17 2107 . C 0 . DP=25;I16=11,12,0,0,783,27185,0,0,1380,82800,0,0,425,9113,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,100:3:0 0,15,133:5:0 +17 2108 . G 0 . DP=25;I16=11,13,0,0,829,29703,0,0,1440,86400,0,0,448,9730,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,122:4:0 0,15,111:5:0 +17 2109 . C 0 . DP=25;I16=11,13,0,0,781,26717,0,0,1440,86400,0,0,446,9746,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,109:4:0 0,15,125:5:0 +17 2110 . G 0 . DP=25;I16=12,12,0,0,804,28134,0,0,1440,86400,0,0,418,9110,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,92:3:0 0,15,117:5:0 +17 2111 . C 0 . DP=25;I16=12,13,0,0,925,35081,0,0,1500,90000,0,0,441,9747,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,134:4:0 0,15,140:5:0 +17 2112 . A 0 . DP=24;I16=12,12,0,0,885,33445,0,0,1440,86400,0,0,440,9782,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,129:4:0 0,15,140:5:0 +17 2113 . G 0 . DP=24;I16=12,12,0,0,871,32641,0,0,1440,86400,0,0,439,9839,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,128:4:0 0,15,134:5:0 +17 2114 . C 0 . DP=24;I16=12,11,0,0,844,32052,0,0,1380,82800,0,0,413,9293,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,103:3:0 0,15,126:5:0 +17 2115 . T 0 . DP=23;I16=11,11,0,0,821,30869,0,0,1320,79200,0,0,412,9342,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,78:2:0 0,15,143:5:0 +17 2116 . C 0 . DP=23;I16=11,12,0,0,890,34892,0,0,1380,82800,0,0,435,9985,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,102:3:0 0,15,152:5:0 +17 2117 . A 0 . DP=23;I16=11,11,0,0,833,32121,0,0,1320,79200,0,0,432,9924,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,118:3:0 0,15,156:5:0 +17 2118 . G 0 . DP=23;I16=12,11,0,0,842,31502,0,0,1380,82800,0,0,429,9835,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,125:4:0 0,15,147:5:0 +17 2119 . G 0 . DP=23;I16=12,11,0,0,823,30553,0,0,1380,82800,0,0,426,9768,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,135:4:0 0,15,137:5:0 +17 2120 . G 0 . DP=24;I16=13,11,0,0,864,32028,0,0,1440,86400,0,0,423,9723,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,137:4:0 0,15,140:5:0 +17 2121 . A 0 . DP=22;I16=11,10,0,0,734,26712,0,0,1260,75600,0,0,398,9074,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,135:4:0 0,12,122:4:0 +17 2122 . T 0 . DP=22;I16=11,10,0,0,752,27278,0,0,1260,75600,0,0,396,8972,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,136:4:0 0,12,123:4:0 +17 2123 . A 0 . DP=22;I16=12,10,0,0,758,27024,0,0,1320,79200,0,0,419,9519,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,120:4:0 0,15,137:5:0 +17 2124 . T 0 . DP=22;I16=12,10,0,0,789,28741,0,0,1320,79200,0,0,417,9465,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,128:4:0 0,15,136:5:0 +17 2125 . T 0 . DP=20;I16=11,8,0,0,696,25704,0,0,1140,68400,0,0,401,9177,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,106:3:0 0,9,93:3:0 +17 2126 . A 0 . DP=20;I16=11,9,0,0,717,25979,0,0,1200,72000,0,0,415,9319,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,133:4:0 0,9,95:3:0 +17 2127 . C 0 . DP=21;I16=11,10,0,0,706,24426,0,0,1260,75600,0,0,413,9221,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,107:4:0 0,9,95:3:0 +17 2128 . G 0 . DP=21;I16=11,10,0,0,677,22633,0,0,1260,75600,0,0,411,9091,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,116:4:0 0,9,72:3:0 +17 2129 . T 0 . DP=21;I16=11,10,0,0,782,29386,0,0,1260,75600,0,0,409,8981,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,140:4:0 0,9,83:3:0 +17 2130 . G 0 . DP=21;I16=11,10,0,0,766,28562,0,0,1260,75600,0,0,407,8891,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,135:4:0 0,9,87:3:0 +17 2131 . T 0 . DP=21;I16=11,10,0,0,732,26216,0,0,1260,75600,0,0,405,8821,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,136:4:0 0,9,79:3:0 +17 2132 . A 0 . DP=21;I16=11,10,0,0,743,26733,0,0,1260,75600,0,0,403,8771,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,135:4:0 0,9,88:3:0 +17 2133 . A 0 . DP=21;I16=11,10,0,0,787,29651,0,0,1260,75600,0,0,401,8741,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,141:4:0 0,9,96:3:0 +17 2134 . C 0 . DP=21;I16=11,10,0,0,804,31100,0,0,1260,75600,0,0,399,8731,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,138:4:0 0,9,86:3:0 +17 2135 . T 0 . DP=22;I16=11,11,0,0,831,32197,0,0,1320,79200,0,0,397,8741,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,153:4:0 0,12,119:4:0 +17 2136 . C 0 . DP=22;I16=11,11,0,0,760,26892,0,0,1320,79200,0,0,395,8721,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,124:4:0 0,12,127:4:0 +17 2137 . G 0 . DP=22;I16=11,11,0,0,745,26047,0,0,1320,79200,0,0,393,8721,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,121:4:0 0,12,102:4:0 +17 2138 . A 0 . DP=22;I16=11,11,0,0,816,30934,0,0,1320,79200,0,0,391,8741,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,128:4:0 0,12,139:4:0 +17 2139 . C 0 . DP=22;I16=11,11,0,0,839,32237,0,0,1320,79200,0,0,389,8781,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,138:4:0 0,12,125:4:0 +17 2140 . A 0 . DP=22;I16=11,11,0,0,826,31300,0,0,1320,79200,0,0,387,8841,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,140:4:0 0,12,138:4:0 +17 2141 . T 0 . DP=21;I16=11,10,0,0,792,30156,0,0,1260,75600,0,0,385,8871,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,137:4:0 0,12,137:4:0 +17 2142 . G 0 . DP=19;I16=11,8,0,0,724,27784,0,0,1140,68400,0,0,385,8919,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,113:3:0 0,12,129:4:0 +17 2143 . T 0 . DP=19;I16=11,8,0,0,650,23454,0,0,1140,68400,0,0,384,8932,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,113:3:0 0,12,120:4:0 +17 2144 . C 0 . DP=19;I16=11,8,0,0,739,29003,0,0,1140,68400,0,0,383,8959,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,108:3:0 0,12,125:4:0 +17 2145 . A 0 . DP=20;I16=12,8,0,0,760,29304,0,0,1200,72000,0,0,381,8951,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,133:4:0 0,12,139:4:0 +17 2146 . G 0 . DP=20;I16=12,8,0,0,745,28105,0,0,1200,72000,0,0,379,8909,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,139:4:0 0,12,127:4:0 +17 2147 . C 0 . DP=20;I16=13,6,0,0,674,24296,0,0,1140,68400,0,0,379,8881,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,127:4:0 0,12,130:4:0 +17 2148 . G 0 . DP=20;I16=12,7,0,0,630,21274,0,0,1140,68400,0,0,365,8537,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,250:11:0 0,12,112:4:0 0,12,120:4:0 +17 2149 . A 0 . DP=20;I16=12,7,0,0,702,26212,0,0,1140,68400,0,0,367,8529,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,138:4:0 0,12,127:4:0 +17 2150 . T 0 . DP=20;I16=13,7,0,0,675,23943,0,0,1200,72000,0,0,383,8713,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,247:11:0 0,12,138:4:0 0,15,139:5:0 +17 2151 . T 0 . DP=20;I16=13,7,0,0,690,24274,0,0,1200,72000,0,0,383,8661,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,251:11:0 0,12,133:4:0 0,15,142:5:0 +17 2152 . G 0 . DP=20;I16=13,7,0,0,693,24713,0,0,1200,72000,0,0,383,8629,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,131:4:0 0,15,146:5:0 +17 2153 . T 0 . DP=19;I16=13,6,0,0,671,24571,0,0,1140,68400,0,0,383,8565,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,230:10:0 0,12,134:4:0 0,15,162:5:0 +17 2154 . C 0 . DP=19;I16=13,6,0,0,703,26955,0,0,1140,68400,0,0,382,8468,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,251:10:0 0,12,131:4:0 0,15,159:5:0 +17 2155 . A 0 . DP=19;I16=13,6,0,0,693,25727,0,0,1140,68400,0,0,381,8389,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,245:10:0 0,12,135:4:0 0,15,156:5:0 +17 2156 . C 0 . DP=19;I16=13,6,0,0,702,26214,0,0,1140,68400,0,0,380,8328,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,125:4:0 0,15,154:5:0 +17 2157 . A 0 . DP=19;I16=13,6,0,0,722,28058,0,0,1140,68400,0,0,379,8285,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,12,141:4:0 0,15,173:5:0 +17 2158 . G 0 . DP=19;I16=13,6,0,0,713,27567,0,0,1140,68400,0,0,378,8260,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,136:4:0 0,15,144:5:0 +17 2159 . G 0 . DP=19;I16=12,6,0,0,662,24744,0,0,1080,64800,0,0,366,8104,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,247:9:0 0,12,126:4:0 0,15,153:5:0 +17 2160 . C 0 . DP=19;I16=12,6,0,0,651,24005,0,0,1080,64800,0,0,364,8038,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,12,119:4:0 0,15,154:5:0 +17 2161 . A 0 . DP=19;I16=13,6,0,0,695,25883,0,0,1140,68400,0,0,369,8005,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,12,121:4:0 0,15,164:5:0 +17 2162 . C 0 . DP=20;I16=13,7,0,0,742,27834,0,0,1200,72000,0,0,365,7911,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,127:4:0 0,15,155:5:0 +17 2163 . T 0 . DP=20;I16=13,7,0,0,763,29517,0,0,1200,72000,0,0,362,7838,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,131:4:0 0,15,175:5:0 +17 2164 . G 0 . DP=20;I16=13,7,0,0,715,26301,0,0,1200,72000,0,0,359,7787,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,116:4:0 0,15,156:5:0 +17 2165 . C 0 . DP=20;I16=13,7,0,0,753,28781,0,0,1200,72000,0,0,355,7709,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,136:4:0 0,15,151:5:0 +17 2166 . T 0 . DP=19;I16=12,7,0,0,711,27211,0,0,1140,68400,0,0,352,7654,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,142:4:0 0,12,140:4:0 +17 2167 . A 0 . DP=19;I16=12,6,0,0,650,23760,0,0,1080,64800,0,0,327,7137,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,12,133:4:0 0,9,111:3:0 +17 2168 . C 0 . DP=19;I16=12,7,0,0,685,25039,0,0,1140,68400,0,0,345,7561,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,130:4:0 0,12,124:4:0 +17 2169 . T 0 . DP=19;I16=12,7,0,0,702,26940,0,0,1140,68400,0,0,341,7525,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,140:4:0 0,12,142:4:0 +17 2170 . C 0 . DP=18;I16=11,7,0,0,665,24861,0,0,1080,64800,0,0,338,7512,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,132:4:0 0,12,135:4:0 +17 2171 . C 0 . DP=20;I16=11,9,0,0,750,28368,0,0,1200,72000,0,0,333,7419,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,136:4:0 0,12,138:4:0 +17 2172 . T 0 . DP=20;I16=11,9,0,0,732,27540,0,0,1200,72000,0,0,330,7346,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,149:4:0 0,12,147:4:0 +17 2173 . G 0 . DP=19;I16=10,9,0,0,704,26534,0,0,1140,68400,0,0,327,7243,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,142:4:0 0,12,133:4:0 +17 2174 . G 0 . DP=19;I16=10,9,0,0,674,24372,0,0,1140,68400,0,0,324,7158,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,126:4:0 0,12,129:4:0 +17 2175 . G 0 . DP=18;I16=9,9,0,0,639,23059,0,0,1080,64800,0,0,322,7090,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,123:4:0 0,12,126:4:0 +17 2176 . G 0 . DP=18;I16=9,9,0,0,621,21815,0,0,1080,64800,0,0,318,6940,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,12,121:4:0 0,12,123:4:0 +17 2177 . T 0 . DP=18;I16=9,9,0,0,547,18051,0,0,1080,64800,0,0,314,6810,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,239:10:0 0,12,83:4:0 0,12,108:4:0 +17 2178 . T 0 . DP=18;I16=9,9,0,0,579,19659,0,0,1080,64800,0,0,310,6700,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,234:10:0 0,12,110:4:0 0,12,118:4:0 +17 2179 . T 0 . DP=18;I16=9,9,0,0,591,20403,0,0,1080,64800,0,0,307,6609,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,239:10:0 0,12,97:4:0 0,12,135:4:0 +17 2180 . T 0 . DP=18;I16=9,9,0,0,616,21524,0,0,1080,64800,0,0,305,6537,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,236:10:0 0,12,122:4:0 0,12,133:4:0 +17 2181 . C 0 . DP=18;I16=9,8,0,0,611,22485,0,0,1020,61200,0,0,293,6385,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,224:9:0 0,12,129:4:0 0,12,150:4:0 +17 2182 . C 0 . DP=18;I16=9,9,0,0,665,24877,0,0,1080,64800,0,0,301,6453,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,125:4:0 0,12,145:4:0 +17 2183 . A 0 . DP=18;I16=9,9,0,0,646,23624,0,0,1080,64800,0,0,299,6441,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,12,123:4:0 0,12,144:4:0 +17 2184 . T 0 . DP=17;I16=8,9,0,0,610,22250,0,0,1020,61200,0,0,298,6448,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,224:9:0 0,12,134:4:0 0,12,136:4:0 +17 2185 . C 0 . DP=16;I16=8,8,0,0,569,20761,0,0,960,57600,0,0,297,6423,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,211:8:0 0,12,128:4:0 0,12,137:4:0 +17 2186 . A 0 . DP=16;I16=8,8,0,0,576,21314,0,0,960,57600,0,0,296,6416,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,204:8:0 0,12,134:4:0 0,12,145:4:0 +17 2187 . A 0 . DP=16;I16=8,8,0,0,562,20396,0,0,960,57600,0,0,295,6427,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,201:8:0 0,12,136:4:0 0,12,135:4:0 +17 2188 . A 0 . DP=17;I16=9,8,0,0,569,19925,0,0,1020,61200,0,0,293,6405,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,214:9:0 0,12,133:4:0 0,12,123:4:0 +17 2189 . C 0 . DP=19;I16=9,10,0,0,645,22647,0,0,1097,65089,0,0,292,6400,0,0;QS=3,0;MQSB=0.934728;MQ0F=0 PL:DP:DV 0,30,230:10:0 0,12,133:4:0 0,15,142:5:0 +17 2190 . C 0 . DP=19;I16=9,10,0,0,604,20072,0,0,1097,65089,0,0,294,6414,0,0;QS=3,0;MQSB=0.934728;MQ0F=0 PL:DP:DV 0,33,238:11:0 0,12,119:4:0 0,12,107:4:0 +17 2191 . C 0 . DP=19;I16=9,10,0,0,647,23007,0,0,1097,65089,0,0,297,6449,0,0;QS=3,0;MQSB=0.934728;MQ0F=0 PL:DP:DV 0,33,251:11:0 0,12,129:4:0 0,12,119:4:0 +17 2192 . T 0 . DP=19;I16=9,10,0,0,659,23723,0,0,1097,65089,0,0,300,6506,0,0;QS=3,0;MQSB=0.934728;MQ0F=0 PL:DP:DV 0,33,253:11:0 0,12,136:4:0 0,12,120:4:0 +17 2193 . C 0 . DP=18;I16=8,10,0,0,642,23934,0,0,1037,61489,0,0,303,6535,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,128:4:0 0,9,87:3:0 +17 2194 . A 0 . DP=18;I16=8,9,0,0,617,22683,0,0,1020,61200,0,0,301,6561,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,12,134:4:0 0,9,98:3:0 +17 2195 . A 0 . DP=18;I16=8,10,0,0,635,23271,0,0,1037,61489,0,0,309,6659,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,128:4:0 0,9,101:3:0 +17 2196 . G 0 . DP=19;I16=8,11,0,0,703,26383,0,0,1097,65089,0,0,312,6754,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,117:4:0 0,12,120:4:0 +17 2197 . A 0 . DP=19;I16=8,11,0,0,735,28599,0,0,1097,65089,0,0,314,6770,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,141:4:0 0,12,125:4:0 +17 2198 . G 0 . DP=19;I16=8,10,0,0,650,24206,0,0,1080,64800,0,0,307,6725,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,129:4:0 0,12,107:4:0 +17 2199 . C 0 . DP=19;I16=8,11,0,0,701,26735,0,0,1097,65089,0,0,318,6862,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,128:4:0 0,12,116:4:0 +17 2200 . T 0 . DP=19;I16=8,11,0,0,710,26768,0,0,1097,65089,0,0,320,6938,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,129:4:0 0,12,114:4:0 +17 2201 . G 0 . DP=17;I16=7,10,0,0,628,23764,0,0,977,57889,0,0,324,7032,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,66:2:0 0,12,119:4:0 +17 2202 . G 0 . DP=17;I16=7,10,0,0,557,19249,0,0,977,57889,0,0,327,7093,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,33,245:11:0 0,6,57:2:0 0,12,115:4:0 +17 2203 . G 0 . DP=17;I16=7,10,0,0,588,21184,0,0,977,57889,0,0,329,7123,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,47:2:0 0,12,116:4:0 +17 2204 . C 0 . DP=17;I16=7,10,0,0,538,18568,0,0,977,57889,0,0,331,7173,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,33,246:11:0 0,6,61:2:0 0,12,99:4:0 +17 2205 . C 0 . DP=18;I16=7,11,0,0,628,22918,0,0,1037,61489,0,0,332,7192,0,0;QS=3,0;MQSB=0.951002;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,68:2:0 0,12,109:4:0 +17 2206 . T 0 . DP=19;I16=7,12,0,0,677,25237,0,0,1097,65089,0,0,334,7230,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,77:2:0 0,12,115:4:0 +17 2207 . G 0 . DP=19;I16=7,11,0,0,663,24717,0,0,1080,64800,0,0,319,6965,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,67:2:0 0,12,110:4:0 +17 2208 . G 0 . DP=21;I16=7,14,0,0,726,26038,0,0,1217,72289,0,0,340,7370,0,0;QS=3,0;MQSB=0.966484;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,110:4:0 0,12,122:4:0 +17 2209 . G 0 . DP=22;I16=8,13,0,0,715,25133,0,0,1237,73369,0,0,325,7075,0,0;QS=3,0;MQSB=0.895122;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,128:5:0 0,12,117:4:0 +17 2210 . G C, 0 . DP=21;I16=7,13,0,1,648,22186,25,625,1177,69769,17,289,331,7165,21,441;QS=2.95442,0.0455764,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.975265;BQB=1;MQ0F=0 PL:DP:DV 0,19,234,33,237,241:12:1 0,15,127,15,127,127:5:0 0,12,113,12,113,113:4:0 +17 2211 . T 0 . DP=21;I16=7,13,0,0,724,27000,0,0,1177,69769,0,0,336,7230,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,141:5:0 0,12,124:4:0 +17 2212 . C 0 . DP=22;I16=8,14,0,0,791,29201,0,0,1254,73658,0,0,364,7850,0,0;QS=3,0;MQSB=0.985548;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,148:5:0 0,12,111:4:0 +17 2213 . A 0 . DP=22;I16=8,14,0,0,767,27327,0,0,1254,73658,0,0,371,8015,0,0;QS=3,0;MQSB=0.985548;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,153:5:0 0,12,112:4:0 +17 2214 . A 0 . DP=22;I16=8,14,0,0,756,26836,0,0,1254,73658,0,0,377,8159,0,0;QS=3,0;MQSB=0.985548;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,153:5:0 0,12,117:4:0 +17 2215 . C 0 . DP=22;I16=8,14,0,0,815,31121,0,0,1254,73658,0,0,381,8229,0,0;QS=3,0;MQSB=0.985548;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,162:5:0 0,12,124:4:0 +17 2216 . T 0 . DP=22;I16=8,14,0,0,815,31233,0,0,1254,73658,0,0,384,8272,0,0;QS=3,0;MQSB=0.985548;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,166:5:0 0,12,124:4:0 +17 2217 . T 0 . DP=22;I16=8,13,0,0,741,26855,0,0,1237,73369,0,0,362,7712,0,0;QS=3,0;MQSB=0.895122;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,155:5:0 0,12,118:4:0 +17 2218 . C 0 . DP=21;I16=7,14,0,0,753,27973,0,0,1194,70058,0,0,391,8423,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,138:4:0 0,12,119:4:0 +17 2219 . C 0 . DP=21;I16=7,13,0,0,757,29125,0,0,1177,69769,0,0,370,7904,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,141:4:0 0,12,122:4:0 +17 2220 . G A, 0 . DP=21;I16=6,2,1,11,256,8364,474,19128,457,26569,720,43200,141,2959,233,5071;QS=0.886504,2.1135,0;VDB=0.532753;SGB=-3.51597;RPB=0.964198;MQB=0.898397;MQSB=0.875769;BQB=0.0354359;MQ0F=0 PL:DP:DV 139,0,130,157,148,255:12:6 69,0,46,75,52,119:4:2 131,12,0,131,12,131:4:4 +17 2221 . G 0 . DP=21;I16=7,13,0,0,738,27922,0,0,1177,69769,0,0,376,8078,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,132:4:0 0,12,120:4:0 +17 2222 . C 0 . DP=21;I16=7,14,0,0,746,28098,0,0,1194,70058,0,0,401,8675,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,135:4:0 0,12,107:4:0 +17 2223 . C 0 . DP=21;I16=7,14,0,0,796,30632,0,0,1194,70058,0,0,401,8671,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,135:4:0 0,12,122:4:0 +17 2224 . T 0 . DP=21;I16=7,14,0,0,811,31599,0,0,1194,70058,0,0,401,8691,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,144:4:0 0,12,123:4:0 +17 2225 . G 0 . DP=21;I16=7,14,0,0,778,29396,0,0,1194,70058,0,0,401,8735,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,133:4:0 0,12,121:4:0 +17 2226 . G 0 . DP=21;I16=7,14,0,0,727,26485,0,0,1194,70058,0,0,401,8803,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,128:4:0 0,12,113:4:0 +17 2227 . G 0 . DP=20;I16=7,12,0,0,663,23985,0,0,1117,66169,0,0,377,8269,0,0;QS=3,0;MQSB=0.879351;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,123:4:0 0,12,114:4:0 +17 2228 . G C, 0 . DP=19;I16=5,12,0,1,643,24791,16,256,1020,61200,17,289,360,8020,25,625;QS=2.9603,0.0397022,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.970092;BQB=1;MQ0F=0 PL:DP:DV 0,17,255,30,255,255:11:1 0,9,95,9,95,95:3:0 0,12,121,12,121,121:4:0 +17 2229 . A 0 . DP=20;I16=6,14,0,0,757,28857,0,0,1134,66458,0,0,406,9138,0,0;QS=3,0;MQSB=0.959189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,138:4:0 0,12,122:4:0 +17 2230 . A 0 . DP=20;I16=6,14,0,0,729,26985,0,0,1134,66458,0,0,409,9291,0,0;QS=3,0;MQSB=0.959189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,141:4:0 0,12,119:4:0 +17 2231 . A 0 . DP=20;I16=6,13,0,0,712,26990,0,0,1117,66169,0,0,386,8790,0,0;QS=3,0;MQSB=0.850016;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,144:4:0 0,12,124:4:0 +17 2232 . C 0 . DP=20;I16=6,14,0,0,751,28657,0,0,1134,66458,0,0,412,9508,0,0;QS=3,0;MQSB=0.959189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,130:4:0 0,12,107:4:0 +17 2233 . T 0 . DP=20;I16=6,14,0,0,774,30432,0,0,1134,66458,0,0,413,9619,0,0;QS=3,0;MQSB=0.959189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,150:4:0 0,12,117:4:0 +17 2234 . G 0 . DP=20;I16=6,14,0,0,719,26621,0,0,1134,66458,0,0,412,9646,0,0;QS=3,0;MQSB=0.959189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,145:4:0 0,12,107:4:0 +17 2235 . G 0 . DP=20;I16=6,14,0,0,728,27036,0,0,1134,66458,0,0,410,9636,0,0;QS=3,0;MQSB=0.959189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,139:4:0 0,12,104:4:0 +17 2236 . G 0 . DP=19;I16=6,13,0,0,705,26985,0,0,1074,62858,0,0,409,9637,0,0;QS=3,0;MQSB=0.965977;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,142:4:0 0,9,84:3:0 +17 2237 . G 0 . DP=19;I16=6,12,0,0,684,26576,0,0,1057,62569,0,0,383,9023,0,0;QS=3,0;MQSB=0.85394;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,141:4:0 0,9,86:3:0 +17 2238 . C 0 . DP=19;I16=5,13,0,0,648,24496,0,0,1037,61489,0,0,381,8993,0,0;QS=3,0;MQSB=0.970092;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,108:3:0 0,9,78:3:0 +17 2239 . A 0 . DP=19;I16=6,11,0,0,634,24178,0,0,997,58969,0,0,373,8935,0,0;QS=3,0;MQSB=0.85832;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,133:4:0 0,6,77:2:0 +17 2240 . A 0 . DP=19;I16=6,13,0,0,731,28595,0,0,1074,62858,0,0,402,9582,0,0;QS=3,0;MQSB=0.965977;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,135:4:0 0,9,101:3:0 +17 2241 . G 0 . DP=19;I16=6,12,0,0,683,26433,0,0,1057,62569,0,0,375,8951,0,0;QS=3,0;MQSB=0.85394;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,126:4:0 0,9,88:3:0 +17 2242 . T 0 . DP=20;I16=5,13,0,0,635,22949,0,0,1057,62569,0,0,370,8944,0,0;QS=3,0;MQSB=0.814433;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,91:3:0 0,9,95:3:0 +17 2243 . A 0 . DP=19;I16=5,14,0,0,704,26274,0,0,1074,62858,0,0,395,9585,0,0;QS=3,0;MQSB=0.933727;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,107:3:0 0,9,99:3:0 +17 2244 . T 0 . DP=19;I16=5,14,0,0,681,25263,0,0,1074,62858,0,0,395,9609,0,0;QS=3,0;MQSB=0.933727;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,89:3:0 0,9,98:3:0 +17 2245 . C 0 . DP=19;I16=5,14,0,0,722,27846,0,0,1074,62858,0,0,394,9592,0,0;QS=3,0;MQSB=0.933727;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,98:3:0 0,9,88:3:0 +17 2246 . A 0 . DP=18;I16=5,12,0,0,597,21693,0,0,997,58969,0,0,367,8861,0,0;QS=3,0;MQSB=0.818731;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,95:3:0 0,6,72:2:0 +17 2247 . C 0 . DP=17;I16=4,13,0,0,639,24373,0,0,954,55658,0,0,391,9391,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,105:3:0 0,6,71:2:0 +17 2248 . C 0 . DP=17;I16=4,13,0,0,669,26863,0,0,954,55658,0,0,390,9306,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,90:3:0 0,6,75:2:0 +17 2249 . A 0 . DP=17;I16=4,13,0,0,677,27371,0,0,954,55658,0,0,389,9231,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,116:3:0 0,6,80:2:0 +17 2250 . G 0 . DP=17;I16=4,13,0,0,654,25800,0,0,954,55658,0,0,388,9166,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,100:3:0 0,6,78:2:0 +17 2251 . A 0 . DP=17;I16=4,13,0,0,673,27327,0,0,954,55658,0,0,387,9111,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,112:3:0 0,6,80:2:0 +17 2252 . G 0 . DP=17;I16=4,12,0,0,647,26249,0,0,937,55369,0,0,361,8441,0,0;QS=3,0;MQSB=0.767432;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,113:3:0 0,6,73:2:0 +17 2253 . A 0 . DP=17;I16=4,13,0,0,641,24643,0,0,954,55658,0,0,385,9031,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,111:3:0 0,6,73:2:0 +17 2254 . T 0 . DP=17;I16=4,12,0,0,615,23821,0,0,937,55369,0,0,358,8332,0,0;QS=3,0;MQSB=0.767432;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,112:3:0 0,6,73:2:0 +17 2255 . G 0 . DP=17;I16=4,13,0,0,677,27243,0,0,954,55658,0,0,380,8844,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,115:3:0 0,6,71:2:0 +17 2256 . A 0 . DP=17;I16=4,13,0,0,656,26088,0,0,954,55658,0,0,377,8741,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,110:3:0 0,6,78:2:0 +17 2257 . G 0 . DP=17;I16=4,12,0,0,627,24863,0,0,937,55369,0,0,349,8023,0,0;QS=3,0;MQSB=0.767432;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,115:3:0 0,6,74:2:0 +17 2258 . C 0 . DP=17;I16=4,13,0,0,667,26403,0,0,954,55658,0,0,371,8565,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,109:3:0 0,6,70:2:0 +17 2259 . T 0 . DP=17;I16=4,13,0,0,646,25334,0,0,954,55658,0,0,368,8492,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,116:3:0 0,6,79:2:0 +17 2260 . T 0 . DP=17;I16=4,13,0,0,638,24178,0,0,954,55658,0,0,365,8429,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,115:3:0 0,6,72:2:0 +17 2261 . T 0 . DP=17;I16=4,13,0,0,633,23799,0,0,954,55658,0,0,362,8376,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,105:3:0 0,6,73:2:0 +17 2262 . A 0 . DP=17;I16=4,13,0,0,628,23438,0,0,954,55658,0,0,359,8333,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,253:12:0 0,9,112:3:0 0,6,74:2:0 +17 2263 . T 0 . DP=17;I16=4,13,0,0,631,23673,0,0,954,55658,0,0,355,8251,0,0;QS=3,0;MQSB=0.90252;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,112:3:0 0,6,74:2:0 +17 2264 . A 0 . DP=17;I16=4,12,0,0,623,24371,0,0,937,55369,0,0,326,7556,0,0;QS=3,0;MQSB=0.767432;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,114:3:0 0,6,75:2:0 +17 2265 . A 0 . DP=18;I16=4,13,0,0,642,24718,0,0,997,58969,0,0,320,7400,0,0;QS=3,0;MQSB=0.762744;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,113:3:0 0,6,75:2:0 +17 2266 . A 0 . DP=19;I16=5,14,0,0,656,23962,0,0,1074,62858,0,0,337,7745,0,0;QS=3,0;MQSB=0.933727;MQ0F=0 PL:DP:DV 0,39,252:13:0 0,12,128:4:0 0,6,75:2:0 +17 2267 . A 0 . DP=20;I16=6,14,0,0,712,26052,0,0,1134,66458,0,0,332,7582,0,0;QS=3,0;MQSB=0.959189;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,134:4:0 0,9,102:3:0 +17 2268 . A 0 . DP=20;I16=6,14,0,0,741,27841,0,0,1134,66458,0,0,327,7391,0,0;QS=3,0;MQSB=0.959189;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,135:4:0 0,9,100:3:0 +17 2269 . T 0 . DP=20;I16=6,13,0,0,681,24751,0,0,1074,62858,0,0,318,7206,0,0;QS=3,0;MQSB=0.965977;MQ0F=0 PL:DP:DV 0,36,246:12:0 0,12,137:4:0 0,9,111:3:0 +17 2270 . A 0 . DP=19;I16=6,12,0,0,652,24154,0,0,1057,62569,0,0,300,6750,0,0;QS=3,0;MQSB=0.85394;MQ0F=0 PL:DP:DV 0,33,244:11:0 0,12,134:4:0 0,9,112:3:0 +17 2271 . A 0 . DP=17;I16=6,11,0,0,654,25406,0,0,954,55658,0,0,316,6944,0,0;QS=3,0;MQSB=0.980001;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,12,142:4:0 0,9,111:3:0 +17 2272 . T 0 . DP=17;I16=6,10,0,0,604,22908,0,0,937,55369,0,0,297,6525,0,0;QS=3,0;MQSB=0.863243;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,12,137:4:0 0,9,111:3:0 +17 2273 . G 0 . DP=17;I16=6,10,0,0,581,22129,0,0,937,55369,0,0,295,6411,0,0;QS=3,0;MQSB=0.863243;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,12,123:4:0 0,9,115:3:0 +17 2274 . G 0 . DP=18;I16=6,11,0,0,621,23109,0,0,997,58969,0,0,293,6313,0,0;QS=3,0;MQSB=0.85832;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,12,132:4:0 0,9,110:3:0 +17 2275 . T 0 . DP=18;I16=6,11,0,0,624,23152,0,0,997,58969,0,0,292,6232,0,0;QS=3,0;MQSB=0.85832;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,12,126:4:0 0,9,113:3:0 +17 2276 . G 0 . DP=20;I16=7,12,0,0,710,26848,0,0,1074,62858,0,0,303,6313,0,0;QS=3,0;MQSB=0.985816;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,129:4:0 0,9,110:3:0 +17 2277 . C 0 . DP=21;I16=8,13,0,0,797,30699,0,0,1194,70058,0,0,303,6247,0,0;QS=3,0;MQSB=0.989565;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,151:5:0 0,12,143:4:0 +17 2278 . T 0 . DP=21;I16=7,13,0,0,736,27790,0,0,1157,68689,0,0,279,5581,0,0;QS=3,0;MQSB=0.962269;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,133:4:0 0,12,148:4:0 +17 2279 . A 0 . DP=20;I16=8,12,0,0,723,27047,0,0,1134,66458,0,0,306,6190,0,0;QS=3,0;MQSB=0.993326;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,155:5:0 0,12,144:4:0 +17 2280 . G 0 . DP=21;I16=8,12,0,0,766,29776,0,0,1177,69769,0,0,299,6085,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,166:5:0 0,12,144:4:0 +17 2281 . C 0 . DP=22;I16=8,13,0,0,784,29748,0,0,1237,73369,0,0,301,6037,0,0;QS=3,0;MQSB=0.895122;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,165:5:0 0,12,140:4:0 +17 2282 . T 0 . DP=22;I16=8,14,0,0,789,29699,0,0,1254,73658,0,0,310,6054,0,0;QS=3,0;MQSB=0.985548;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,162:5:0 0,12,150:4:0 +17 2283 . G 0 . DP=22;I16=8,14,0,0,798,29774,0,0,1254,73658,0,0,312,6054,0,0;QS=3,0;MQSB=0.985548;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,158:5:0 0,12,142:4:0 +17 2284 . G 0 . DP=22;I16=7,14,0,0,760,28408,0,0,1194,70058,0,0,294,5664,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,130:4:0 0,12,141:4:0 +17 2285 . G 0 . DP=23;I16=9,14,0,0,844,31592,0,0,1314,77258,0,0,311,5909,0,0;QS=3,0;MQSB=0.992095;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,152:5:0 0,12,144:4:0 +17 2286 . C 0 . DP=23;I16=9,14,0,0,854,32244,0,0,1314,77258,0,0,311,5869,0,0;QS=3,0;MQSB=0.992095;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,155:5:0 0,12,130:4:0 +17 2287 . A 0 . DP=23;I16=9,14,0,0,818,30288,0,0,1314,77258,0,0,311,5869,0,0;QS=3,0;MQSB=0.992095;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,166:5:0 0,12,143:4:0 +17 2288 . T 0 . DP=22;I16=8,14,0,0,794,29190,0,0,1254,73658,0,0,312,5908,0,0;QS=3,0;MQSB=0.985548;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,158:5:0 0,12,142:4:0 +17 2289 . G 0 . DP=21;I16=8,13,0,0,723,25835,0,0,1237,73369,0,0,314,5984,0,0;QS=3,0;MQSB=0.895122;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,154:5:0 0,12,126:4:0 +17 2290 . G 0 . DP=20;I16=7,13,0,0,748,28318,0,0,1177,69769,0,0,318,6094,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,149:5:0 0,9,114:3:0 +17 2291 . T 0 . DP=20;I16=7,13,0,0,731,27165,0,0,1177,69769,0,0,322,6186,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,151:5:0 0,9,112:3:0 +17 2292 . G 0 . DP=20;I16=7,13,0,0,749,28747,0,0,1177,69769,0,0,325,6259,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,156:5:0 0,9,109:3:0 +17 2293 . G 0 . DP=20;I16=7,13,0,0,739,27903,0,0,1177,69769,0,0,327,6311,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,156:5:0 0,9,112:3:0 +17 2294 . C 0 . DP=21;I16=7,14,0,0,775,29453,0,0,1237,73369,0,0,329,6391,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,169:5:0 0,9,114:3:0 +17 2295 . T 0 . DP=21;I16=7,14,0,0,773,29209,0,0,1237,73369,0,0,331,6451,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,164:5:0 0,9,115:3:0 +17 2296 . T 0 . DP=21;I16=7,14,0,0,756,27780,0,0,1237,73369,0,0,333,6543,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,160:5:0 0,9,106:3:0 +17 2297 . G 0 . DP=20;I16=7,13,0,0,736,27692,0,0,1177,69769,0,0,336,6666,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,165:5:0 0,6,74:2:0 +17 2298 . C 0 . DP=21;I16=7,14,0,0,778,29300,0,0,1237,73369,0,0,339,6819,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,139:5:0 0,9,106:3:0 +17 2299 . A 0 . DP=21;I16=7,14,0,0,714,25282,0,0,1237,73369,0,0,343,7003,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,128:5:0 0,9,110:3:0 +17 2300 . C 0 . DP=21;I16=7,13,0,0,687,24749,0,0,1177,69769,0,0,326,6768,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,148:5:0 0,9,109:3:0 +17 2301 . C 0 . DP=23;I16=7,15,0,0,802,30292,0,0,1266,74210,0,0,349,7363,0,0;QS=3,0;MQSB=0.970024;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,147:5:0 0,9,116:3:0 +17 2302 . T 0 . DP=23;I16=7,16,0,0,860,32956,0,0,1326,77810,0,0,354,7496,0,0;QS=3,0;MQSB=0.964916;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,166:5:0 0,12,150:4:0 +17 2303 . G 0 . DP=23;I16=7,16,0,0,817,29823,0,0,1326,77810,0,0,356,7604,0,0;QS=3,0;MQSB=0.964916;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,151:5:0 0,12,139:4:0 +17 2304 . T 0 . DP=23;I16=7,16,0,0,802,28628,0,0,1326,77810,0,0,357,7691,0,0;QS=3,0;MQSB=0.964916;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,148:5:0 0,12,140:4:0 +17 2305 . A 0 . DP=22;I16=7,14,0,0,725,25585,0,0,1237,73369,0,0,355,7791,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,36,248:12:0 0,15,155:5:0 0,12,129:4:0 +17 2306 . A 0 . DP=21;I16=7,14,0,0,727,26841,0,0,1206,70610,0,0,361,7899,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,36,246:12:0 0,15,168:5:0 0,12,130:4:0 +17 2307 . T 0 . DP=21;I16=7,14,0,0,751,27427,0,0,1206,70610,0,0,362,7964,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,36,251:12:0 0,15,165:5:0 0,12,141:4:0 +17 2308 . C 0 . DP=21;I16=7,14,0,0,735,26675,0,0,1206,70610,0,0,363,8051,0,0;QS=3,0;MQSB=0.975265;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,144:5:0 0,12,146:4:0 +17 2309 . C A, 0 . DP=19;I16=7,11,0,1,604,21364,16,256,1057,62569,29,841,358,8094,8,64;QS=2.95676,0.0432432,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.985816;BQB=1;MQ0F=0 PL:DP:DV 0,20,224,33,227,230:12:1 0,9,94,9,94,94:3:0 0,12,138,12,138,138:4:0 +17 2310 . C 0 . DP=18;I16=6,12,0,0,668,25392,0,0,1049,62041,0,0,370,8282,0,0;QS=3,0;MQSB=0.961295;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,80:2:0 0,12,139:4:0 +17 2311 . A 0 . DP=19;I16=7,12,0,0,707,26855,0,0,1109,65641,0,0,373,8371,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,78:2:0 0,12,137:4:0 +17 2312 . G 0 . DP=20;I16=7,12,0,0,736,29118,0,0,1109,65641,0,0,364,8306,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,82:2:0 0,9,122:3:0 +17 2313 . C 0 . DP=20;I16=7,13,0,0,723,27231,0,0,1169,69241,0,0,382,8596,0,0;QS=3,0;MQSB=0.962269;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,76:2:0 0,12,130:4:0 +17 2314 . A 0 . DP=21;I16=7,12,0,0,630,22184,0,0,1109,65641,0,0,372,8510,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,78:2:0 0,9,115:3:0 +17 2315 . C 0 . DP=23;I16=7,14,0,0,739,26861,0,0,1229,72841,0,0,392,8892,0,0;QS=3,0;MQSB=0.966484;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,71:2:0 0,12,135:4:0 +17 2316 . T 0 . DP=23;I16=8,15,0,0,826,30690,0,0,1349,80041,0,0,408,9102,0,0;QS=3,0;MQSB=0.967216;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,105:3:0 0,15,170:5:0 +17 2317 . T 0 . DP=24;I16=7,16,0,0,766,27014,0,0,1349,80041,0,0,411,9211,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,78:2:0 0,15,170:5:0 +17 2318 . T 0 . DP=24;I16=8,14,0,0,757,27433,0,0,1320,79200,0,0,379,8449,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,91:3:0 0,15,165:5:0 +17 2319 . G 0 . DP=24;I16=6,16,0,0,827,31577,0,0,1289,76441,0,0,398,8882,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,43:1:0 0,15,167:5:0 +17 2320 . G 0 . DP=23;I16=7,16,0,0,803,29077,0,0,1349,80041,0,0,435,9675,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,87:3:0 0,15,157:5:0 +17 2321 . G 0 . DP=23;I16=7,16,0,0,804,29368,0,0,1349,80041,0,0,442,9840,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,79:3:0 0,15,169:5:0 +17 2322 . A 0 . DP=24;I16=7,17,0,0,860,32116,0,0,1409,83641,0,0,449,10027,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,95:3:0 0,15,178:5:0 +17 2323 . G 0 . DP=24;I16=7,17,0,0,863,31887,0,0,1409,83641,0,0,457,10237,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,88:3:0 0,15,153:5:0 +17 2324 . G 0 . DP=24;I16=7,16,0,0,786,27932,0,0,1349,80041,0,0,462,10416,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,88:3:0 0,15,161:5:0 +17 2325 . C 0 . DP=24;I16=7,15,0,0,730,25576,0,0,1289,76441,0,0,427,9625,0,0;QS=3,0;MQSB=0.970024;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,102:3:0 0,12,130:4:0 +17 2326 . C 0 . DP=24;I16=7,15,0,0,709,23523,0,0,1320,79200,0,0,426,9498,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,241:15:0 0,9,95:3:0 0,12,133:4:0 +17 2327 . G 0 . DP=24;I16=7,17,0,0,817,29275,0,0,1409,83641,0,0,481,10891,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,81:3:0 0,15,158:5:0 +17 2328 . A 0 . DP=24;I16=6,17,0,0,814,29804,0,0,1349,80041,0,0,461,10427,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,82:3:0 0,15,172:5:0 +17 2329 . G 0 . DP=23;I16=6,16,0,0,755,27641,0,0,1289,76441,0,0,477,11005,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,63:2:0 0,15,160:5:0 +17 2330 . C 0 . DP=24;I16=7,17,0,0,875,33131,0,0,1409,83641,0,0,498,11424,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,87:3:0 0,18,181:6:0 +17 2331 . T 0 . DP=24;I16=7,17,0,0,862,31882,0,0,1409,83641,0,0,505,11635,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,106:3:0 0,18,200:6:0 +17 2332 . A 0 . DP=25;I16=8,17,0,0,926,35412,0,0,1469,87241,0,0,512,11864,0,0;QS=3,0;MQSB=0.973216;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,97:3:0 0,18,204:6:0 +17 2333 . G 0 . DP=26;I16=8,17,0,0,923,35129,0,0,1469,87241,0,0,494,11436,0,0;QS=3,0;MQSB=0.973216;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,97:3:0 0,18,189:6:0 +17 2334 . G 0 . DP=26;I16=8,18,0,0,928,34574,0,0,1529,90841,0,0,527,12277,0,0;QS=3,0;MQSB=0.975611;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,93:3:0 0,21,202:7:0 +17 2335 . A 0 . DP=26;I16=8,18,0,0,967,36793,0,0,1529,90841,0,0,535,12513,0,0;QS=3,0;MQSB=0.975611;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,105:3:0 0,21,214:7:0 +17 2336 . G 0 . DP=26;I16=8,18,0,0,962,36346,0,0,1529,90841,0,0,543,12769,0,0;QS=3,0;MQSB=0.975611;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,92:3:0 0,21,204:7:0 +17 2337 . G 0 . DP=26;I16=7,18,0,0,895,32981,0,0,1469,87241,0,0,527,12465,0,0;QS=3,0;MQSB=0.977814;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,74:2:0 0,21,204:7:0 +17 2338 . A 0 . DP=26;I16=8,18,0,0,892,31758,0,0,1529,90841,0,0,556,13186,0,0;QS=3,0;MQSB=0.975611;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,87:3:0 0,21,194:7:0 +17 2339 . T 0 . DP=26;I16=7,18,0,0,827,28921,0,0,1469,87241,0,0,537,12769,0,0;QS=3,0;MQSB=0.977814;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,55:2:0 0,21,200:7:0 +17 2340 . C 0 . DP=25;I16=7,18,0,0,792,25816,0,0,1469,87241,0,0,541,12893,0,0;QS=3,0;MQSB=0.977814;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,57:2:0 0,21,173:7:0 +17 2341 . G 0 . DP=25;I16=6,17,0,0,771,26477,0,0,1349,80041,0,0,494,11732,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,3,41:1:0 0,21,186:7:0 +17 2342 . T 0 . DP=24;I16=6,17,0,0,863,32711,0,0,1349,80041,0,0,523,12459,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,3,43:1:0 0,21,214:7:0 +17 2343 . T 0 . DP=24;I16=6,16,0,0,770,28230,0,0,1289,76441,0,0,504,12032,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,44:1:0 0,21,213:7:0 +17 2344 . T 0 . DP=24;I16=7,17,0,0,843,30483,0,0,1409,83641,0,0,552,13124,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,56:2:0 0,21,202:7:0 +17 2345 . G 0 . DP=24;I16=7,17,0,0,897,34121,0,0,1409,83641,0,0,554,13162,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,77:2:0 0,21,206:7:0 +17 2346 . A 0 . DP=24;I16=7,17,0,0,908,34818,0,0,1409,83641,0,0,556,13212,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,68:2:0 0,21,220:7:0 +17 2347 . G 0 . DP=24;I16=6,17,0,0,824,30406,0,0,1349,80041,0,0,533,12649,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,3,39:1:0 0,21,190:7:0 +17 2348 . T 0 . DP=24;I16=7,16,0,0,745,25653,0,0,1349,80041,0,0,544,13072,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,64:2:0 0,18,183:6:0 +17 2349 . C 0 . DP=24;I16=6,17,0,0,804,29224,0,0,1349,80041,0,0,534,12656,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,3,36:1:0 0,21,200:7:0 +17 2350 . C 0 . DP=25;I16=7,17,0,0,869,31905,0,0,1409,83641,0,0,534,12652,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,63:2:0 0,21,198:7:0 +17 2351 . A 0 . DP=25;I16=8,17,0,0,945,36169,0,0,1469,87241,0,0,559,13237,0,0;QS=3,0;MQSB=0.973216;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,74:2:0 0,21,222:7:0 +17 2352 . G 0 . DP=25;I16=7,17,0,0,893,34005,0,0,1409,83641,0,0,533,12539,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,41:1:0 0,21,207:7:0 +17 2353 . C 0 . DP=24;I16=7,17,0,0,866,31864,0,0,1409,83641,0,0,531,12435,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,41:1:0 0,21,205:7:0 +17 2354 . A 0 . DP=24;I16=7,17,0,0,880,33206,0,0,1409,83641,0,0,529,12351,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,43:1:0 0,21,214:7:0 +17 2355 . G 0 . DP=24;I16=7,17,0,0,871,32261,0,0,1409,83641,0,0,526,12238,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,39:1:0 0,21,195:7:0 +17 2356 . T 0 . DP=24;I16=7,17,0,0,887,33305,0,0,1409,83641,0,0,521,12047,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,43:1:0 0,21,219:7:0 +17 2357 . T 0 . DP=24;I16=7,17,0,0,899,34225,0,0,1409,83641,0,0,516,11878,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,43:1:0 0,21,220:7:0 +17 2358 . T 0 . DP=24;I16=7,17,0,0,913,34891,0,0,1409,83641,0,0,510,11680,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,40:1:0 0,21,218:7:0 +17 2359 . G 0 . DP=25;I16=7,17,0,0,898,34048,0,0,1409,83641,0,0,503,11451,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,39:1:0 0,21,209:7:0 +17 2360 . A 0 . DP=25;I16=7,18,0,0,959,37113,0,0,1469,87241,0,0,514,11552,0,0;QS=3,0;MQSB=0.977814;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,72:2:0 0,21,222:7:0 +17 2361 . G 0 . DP=25;I16=7,17,0,0,850,30946,0,0,1409,83641,0,0,482,10726,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,67:2:0 0,18,168:6:0 +17 2362 . A 0 . DP=25;I16=7,17,0,0,762,25482,0,0,1409,83641,0,0,475,10547,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,51:2:0 0,18,159:6:0 +17 2363 . C 0 . DP=25;I16=7,18,0,0,875,31837,0,0,1469,87241,0,0,493,11015,0,0;QS=3,0;MQSB=0.977814;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,65:2:0 0,21,187:7:0 +17 2364 . C 0 . DP=25;I16=7,18,0,0,927,34965,0,0,1469,87241,0,0,486,10880,0,0;QS=3,0;MQSB=0.977814;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,64:2:0 0,21,201:7:0 +17 2365 . A 0 . DP=24;I16=7,17,0,0,908,34754,0,0,1409,83641,0,0,479,10717,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,65:2:0 0,21,221:7:0 +17 2366 . G 0 . DP=25;I16=7,17,0,0,912,35074,0,0,1440,86400,0,0,447,9951,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,58:2:0 0,21,206:7:0 +17 2367 . C 0 . DP=25;I16=7,17,0,0,872,32088,0,0,1409,83641,0,0,440,9782,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,36:1:0 0,21,197:7:0 +17 2368 . C 0 . DP=24;I16=6,17,0,0,871,33801,0,0,1349,80041,0,0,434,9634,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,3,39:1:0 0,18,180:6:0 +17 2369 . T 0 . DP=24;I16=6,18,0,0,877,33009,0,0,1409,83641,0,0,452,10082,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,49:2:0 0,18,179:6:0 +17 2370 . G 0 . DP=24;I16=6,18,0,0,899,34289,0,0,1409,83641,0,0,445,9927,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,56:2:0 0,18,179:6:0 +17 2371 . G 0 . DP=24;I16=6,18,0,0,880,33088,0,0,1409,83641,0,0,438,9794,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,51:2:0 0,18,177:6:0 +17 2372 . C 0 . DP=24;I16=6,18,0,0,827,29615,0,0,1409,83641,0,0,431,9683,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,47:2:0 0,18,163:6:0 +17 2373 . C 0 . DP=24;I16=6,18,0,0,886,33212,0,0,1409,83641,0,0,424,9594,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,58:2:0 0,18,166:6:0 +17 2374 . A 0 . DP=23;I16=6,17,0,0,844,31230,0,0,1349,80041,0,0,417,9477,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,66:2:0 0,18,177:6:0 +17 2375 . A 0 . DP=23;I16=5,17,0,0,788,28340,0,0,1289,76441,0,0,409,9333,0,0;QS=3,0;MQSB=0.981001;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,64:2:0 0,18,171:6:0 +17 2376 . T 0 . DP=22;I16=5,17,0,0,778,27804,0,0,1289,76441,0,0,401,9161,0,0;QS=3,0;MQSB=0.981001;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,62:2:0 0,18,162:6:0 +17 2377 . A 0 . DP=21;I16=4,17,0,0,704,24488,0,0,1229,72841,0,0,394,9008,0,0;QS=3,0;MQSB=0.984085;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,49:2:0 0,15,135:5:0 +17 2378 . C 0 . DP=20;I16=4,16,0,0,626,20138,0,0,1169,69241,0,0,388,8872,0,0;QS=3,0;MQSB=0.982301;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,15:1:0 0,15,108:5:0 +17 2379 . G 0 . DP=20;I16=4,16,0,0,714,25924,0,0,1169,69241,0,0,382,8752,0,0;QS=3,0;MQSB=0.982301;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,34:1:0 0,15,140:5:0 +17 2380 . G 0 . DP=19;I16=4,14,0,0,672,25672,0,0,1049,62041,0,0,352,8022,0,0;QS=3,0;MQSB=0.977696;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,18:1:0 0,15,134:5:0 +17 2381 . C 0 . DP=18;I16=4,14,0,0,676,25626,0,0,1049,62041,0,0,373,8555,0,0;QS=3,0;MQSB=0.977696;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,28:1:0 0,15,133:5:0 +17 2382 . A 0 . DP=19;I16=5,14,0,0,669,23995,0,0,1109,65641,0,0,369,8475,0,0;QS=3,0;MQSB=0.97357;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,28:1:0 0,15,131:5:0 +17 2383 . A 0 . DP=19;I16=5,14,0,0,686,25162,0,0,1109,65641,0,0,365,8359,0,0;QS=3,0;MQSB=0.97357;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,26:1:0 0,15,140:5:0 +17 2384 . A 0 . DP=19;I16=5,14,0,0,649,22943,0,0,1109,65641,0,0,360,8210,0,0;QS=3,0;MQSB=0.97357;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,13:1:0 0,15,132:5:0 +17 2385 . A 0 . DP=18;I16=4,14,0,0,643,23235,0,0,1049,62041,0,0,356,8078,0,0;QS=3,0;MQSB=0.977696;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,38:1:0 0,15,134:5:0 +17 2386 . C 0 . DP=18;I16=4,14,0,0,652,24008,0,0,1049,62041,0,0,351,7913,0,0;QS=3,0;MQSB=0.977696;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,25:1:0 0,15,130:5:0 +17 2387 . C 0 . DP=18;I16=4,14,0,0,667,25007,0,0,1049,62041,0,0,345,7717,0,0;QS=3,0;MQSB=0.977696;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,25:1:0 0,15,128:5:0 +17 2388 . C 0 . DP=18;I16=4,14,0,0,691,26659,0,0,1049,62041,0,0,339,7541,0,0;QS=3,0;MQSB=0.977696;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,39:1:0 0,15,134:5:0 +17 2389 . A 0 . DP=19;I16=5,14,0,0,682,24912,0,0,1109,65641,0,0,333,7385,0,0;QS=3,0;MQSB=0.97357;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,35:1:0 0,15,140:5:0 +17 2390 . G 0 . DP=18;I16=5,13,0,0,642,23418,0,0,1049,62041,0,0,328,7200,0,0;QS=3,0;MQSB=0.970092;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,27:1:0 0,15,126:5:0 +17 2391 . T 0 . DP=18;I16=5,12,0,0,624,23122,0,0,989,58441,0,0,298,6412,0,0;QS=2,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,0,0:0:0 0,15,140:5:0 +17 2392 . C 0 . DP=18;I16=5,12,0,0,660,25910,0,0,989,58441,0,0,291,6171,0,0;QS=2,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,0,0:0:0 0,15,131:5:0 +17 2393 . T 0 . DP=18;I16=5,13,0,0,669,25099,0,0,1049,62041,0,0,309,6577,0,0;QS=3,0;MQSB=0.970092;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,38:1:0 0,15,134:5:0 +17 2394 . C 0 . DP=17;I16=5,12,0,0,653,25323,0,0,989,58441,0,0,303,6379,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,29:1:0 0,15,133:5:0 +17 2395 . T 0 . DP=17;I16=5,12,0,0,613,22621,0,0,989,58441,0,0,297,6201,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,19:1:0 0,15,128:5:0 +17 2396 . A 0 . DP=17;I16=5,11,0,0,584,21426,0,0,929,54841,0,0,266,5418,0,0;QS=2,0;MQSB=0.960687;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,0,0:0:0 0,15,130:5:0 +17 2397 . C 0 . DP=18;I16=5,13,0,0,650,24046,0,0,1049,62041,0,0,284,5856,0,0;QS=3,0;MQSB=0.970092;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,18:1:0 0,15,129:5:0 +17 2398 . A 0 . DP=18;I16=5,13,0,0,617,21907,0,0,1049,62041,0,0,278,5692,0,0;QS=3,0;MQSB=0.970092;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,19:1:0 0,15,128:5:0 +17 2399 . A 0 . DP=17;I16=5,11,0,0,592,22176,0,0,929,54841,0,0,248,4926,0,0;QS=2,0;MQSB=0.960687;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,0,0:0:0 0,12,115:4:0 +17 2400 . A 0 . DP=16;I16=5,11,0,0,576,21010,0,0,929,54841,0,0,269,5431,0,0;QS=3,0;MQSB=0.960687;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,26:1:0 0,9,99:3:0 +17 2401 . A 0 . DP=17;I16=6,11,0,0,594,21126,0,0,989,58441,0,0,265,5331,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,23:1:0 0,9,98:3:0 +17 2402 . A 0 . DP=17;I16=6,11,0,0,606,21986,0,0,989,58441,0,0,262,5252,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,27:1:0 0,9,99:3:0 +17 2403 . A 0 . DP=17;I16=6,11,0,0,608,22130,0,0,989,58441,0,0,259,5195,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,21:1:0 0,9,97:3:0 +17 2404 . T 0 . DP=17;I16=6,11,0,0,567,19449,0,0,989,58441,0,0,256,5160,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,14:1:0 0,9,87:3:0 +17 2405 . A 0 . DP=18;I16=7,11,0,0,618,21666,0,0,1049,62041,0,0,253,5147,0,0;QS=3,0;MQSB=0.951002;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,17:1:0 0,9,88:3:0 +17 2406 . C 0 . DP=18;I16=7,11,0,0,676,25664,0,0,1049,62041,0,0,250,5108,0,0;QS=3,0;MQSB=0.951002;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,27:1:0 0,9,90:3:0 +17 2407 . A 0 . DP=19;I16=8,11,0,0,673,24197,0,0,1109,65641,0,0,246,5046,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,3,34:1:0 0,9,89:3:0 +17 2408 . A 0 . DP=18;I16=8,10,0,0,619,21951,0,0,1049,62041,0,0,243,4961,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,3,22:1:0 0,6,73:2:0 +17 2409 . A 0 . DP=17;I16=8,9,0,0,615,22687,0,0,1020,61200,0,0,240,4852,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,39:1:0 0,6,74:2:0 +17 2410 . A 0 . DP=17;I16=8,9,0,0,604,21938,0,0,1020,61200,0,0,237,4769,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,39:1:0 0,6,73:2:0 +17 2411 . A 0 . DP=16;I16=7,9,0,0,567,20551,0,0,960,57600,0,0,235,4711,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,25:1:0 0,6,70:2:0 +17 2412 . A 0 . DP=15;I16=7,8,0,0,527,18903,0,0,900,54000,0,0,234,4676,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,21:1:0 0,6,70:2:0 +17 2413 . C 0 . DP=15;I16=7,8,0,0,559,21161,0,0,900,54000,0,0,233,4663,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,22:1:0 0,6,72:2:0 +17 2414 . A 0 . DP=16;I16=8,8,0,0,570,20822,0,0,929,54841,0,0,232,4672,0,0;QS=3,0;MQSB=0.915545;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,25:1:0 0,6,73:2:0 +17 2415 . A 0 . DP=16;I16=9,7,0,0,574,20768,0,0,929,54841,0,0,232,4652,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,30:1:0 0,6,64:2:0 +17 2416 . C 0 . DP=17;I16=8,8,0,0,576,21424,0,0,960,57600,0,0,231,4649,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,42:2:0 0,6,68:2:0 +17 2417 . T 0 . DP=17;I16=10,7,0,0,612,22740,0,0,958,55682,0,0,235,4627,0,0;QS=3,0;MQSB=0.79189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,57:2:0 0,9,92:3:0 +17 2418 . A 0 . DP=17;I16=10,7,0,0,624,23210,0,0,958,55682,0,0,238,4626,0,0;QS=3,0;MQSB=0.79189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,62:2:0 0,9,105:3:0 +17 2419 . G 0 . DP=19;I16=11,7,0,0,651,24113,0,0,1018,59282,0,0,241,4651,0,0;QS=3,0;MQSB=0.817948;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,51:2:0 0,12,126:4:0 +17 2420 . C 0 . DP=19;I16=11,8,0,0,663,23999,0,0,1078,62882,0,0,246,4704,0,0;QS=3,0;MQSB=0.803979;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,44:2:0 0,12,127:4:0 +17 2421 . C 0 . DP=19;I16=10,8,0,0,657,24779,0,0,1049,62041,0,0,244,4738,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,45:2:0 0,12,126:4:0 +17 2422 . A 0 . DP=18;I16=11,6,0,0,647,24747,0,0,958,55682,0,0,238,4538,0,0;QS=3,0;MQSB=0.833753;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,33:1:0 0,12,137:4:0 +17 2423 . G 0 . DP=18;I16=11,6,0,0,634,24250,0,0,958,55682,0,0,258,4972,0,0;QS=3,0;MQSB=0.833753;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,54:2:0 0,12,126:4:0 +17 2424 . G 0 . DP=18;I16=10,6,0,0,595,22361,0,0,929,54841,0,0,240,4714,0,0;QS=3,0;MQSB=0.948436;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,36:1:0 0,12,126:4:0 +17 2425 . C 0 . DP=18;I16=10,7,0,0,596,21716,0,0,989,58441,0,0,260,5074,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,45:2:0 0,12,114:4:0 +17 2426 . G 0 . DP=18;I16=10,7,0,0,550,18088,0,0,989,58441,0,0,263,5171,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,33,232:11:0 0,6,59:2:0 0,12,113:4:0 +17 2427 . T 0 . DP=18;I16=11,6,0,0,618,22654,0,0,958,55682,0,0,275,5403,0,0;QS=3,0;MQSB=0.833753;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,62:2:0 0,9,99:3:0 +17 2428 . G 0 . DP=18;I16=11,7,0,0,649,24633,0,0,1018,59282,0,0,281,5535,0,0;QS=3,0;MQSB=0.817948;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,48:2:0 0,12,128:4:0 +17 2429 . G 0 . DP=18;I16=10,7,0,0,553,19057,0,0,989,58441,0,0,269,5459,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,33,241:11:0 0,6,55:2:0 0,12,117:4:0 +17 2430 . T A, 0 . DP=18;I16=10,7,1,0,552,18556,21,441,989,58441,29,841,271,5603,16,256;QS=2.94278,0.0572207,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.817948;BQB=1;MQ0F=0 PL:DP:DV 0,15,212,33,215,222:12:1 0,6,60,6,60,60:2:0 0,12,125,12,125,125:4:0 +17 2431 . G 0 . DP=18;I16=11,5,0,0,580,21766,0,0,898,52082,0,0,268,5764,0,0;QS=3,0;MQSB=0.851779;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,37:1:0 0,9,98:3:0 +17 2432 . G 0 . DP=17;I16=10,7,0,0,593,21479,0,0,958,55682,0,0,295,6179,0,0;QS=3,0;MQSB=0.79189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,53:2:0 0,9,97:3:0 +17 2433 . T 0 . DP=17;I16=10,7,0,0,577,20425,0,0,958,55682,0,0,299,6321,0,0;QS=3,0;MQSB=0.79189;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,57:2:0 0,9,94:3:0 +17 2434 . G 0 . DP=17;I16=10,6,0,0,546,19340,0,0,929,54841,0,0,284,6082,0,0;QS=3,0;MQSB=0.948436;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,46:2:0 0,6,62:2:0 +17 2435 . C 0 . DP=18;I16=12,5,0,0,597,21843,0,0,958,55682,0,0,304,6626,0,0;QS=3,0;MQSB=0.870325;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,6,58:2:0 0,6,60:2:0 +17 2436 . A 0 . DP=18;I16=11,6,0,0,545,18599,0,0,989,58441,0,0,295,6379,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,64:3:0 0,6,61:2:0 +17 2437 . C 0 . DP=18;I16=11,5,0,0,573,21195,0,0,929,54841,0,0,297,6541,0,0;QS=3,0;MQSB=0.960687;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,63:2:0 0,6,63:2:0 +17 2438 . A 0 . DP=19;I16=12,6,0,0,583,20111,0,0,1018,59282,0,0,328,7322,0,0;QS=3,0;MQSB=0.85394;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,65:2:0 0,6,65:2:0 +17 2439 . C 0 . DP=19;I16=11,7,0,0,635,22997,0,0,1049,62041,0,0,314,6974,0,0;QS=3,0;MQSB=0.951002;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,91:3:0 0,6,57:2:0 +17 2440 . C 0 . DP=21;I16=13,7,0,0,701,26195,0,0,1138,66482,0,0,346,7840,0,0;QS=3,0;MQSB=0.857404;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,114:4:0 0,6,66:2:0 +17 2441 . T 0 . DP=21;I16=13,8,0,0,788,29910,0,0,1198,70082,0,0,360,8068,0,0;QS=3,0;MQSB=0.845496;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,164:5:0 0,6,67:2:0 +17 2442 . G 0 . DP=20;I16=12,7,0,0,695,25957,0,0,1109,65641,0,0,342,7596,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,128:4:0 0,6,66:2:0 +17 2443 . T 0 . DP=20;I16=13,7,0,0,697,24685,0,0,1138,66482,0,0,373,8345,0,0;QS=3,0;MQSB=0.857404;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,130:4:0 0,6,64:2:0 +17 2444 . A 0 . DP=21;I16=13,8,0,0,755,27981,0,0,1198,70082,0,0,379,8489,0,0;QS=3,0;MQSB=0.845496;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,140:4:0 0,6,64:2:0 +17 2445 . G 0 . DP=21;I16=12,8,0,0,731,27427,0,0,1169,69241,0,0,359,7927,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,130:4:0 0,6,65:2:0 +17 2446 . T 0 . DP=21;I16=13,8,0,0,723,25707,0,0,1198,70082,0,0,389,8633,0,0;QS=3,0;MQSB=0.845496;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,128:4:0 0,6,65:2:0 +17 2447 . C 0 . DP=22;I16=14,8,0,0,770,27950,0,0,1258,73682,0,0,394,8732,0,0;QS=3,0;MQSB=0.86151;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,127:4:0 0,6,64:2:0 +17 2448 . C 0 . DP=23;I16=14,7,0,0,727,26165,0,0,1167,67323,0,0,388,8674,0,0;QS=3,0;MQSB=0.735784;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,129:5:0 0,6,66:2:0 +17 2449 . C 0 . DP=23;I16=13,8,0,0,727,26415,0,0,1198,70082,0,0,363,7787,0,0;QS=3,0;MQSB=0.845496;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,128:5:0 0,6,62:2:0 +17 2450 . A 0 . DP=22;I16=12,8,0,0,673,24267,0,0,1138,66482,0,0,371,7959,0,0;QS=3,0;MQSB=0.826565;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,143:5:0 0,6,65:2:0 +17 2451 . G 0 . DP=22;I16=14,8,0,0,821,31595,0,0,1227,70923,0,0,429,9401,0,0;QS=3,0;MQSB=0.715049;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,151:5:0 0,6,67:2:0 +17 2452 . C 0 . DP=22;I16=14,8,0,0,743,26557,0,0,1227,70923,0,0,437,9613,0,0;QS=3,0;MQSB=0.715049;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,137:5:0 0,6,66:2:0 +17 2453 . T 0 . DP=22;I16=14,8,0,0,775,28215,0,0,1227,70923,0,0,445,9845,0,0;QS=3,0;MQSB=0.715049;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,143:5:0 0,6,68:2:0 +17 2454 . A 0 . DP=22;I16=14,8,0,0,721,24545,0,0,1227,70923,0,0,453,10097,0,0;QS=3,0;MQSB=0.715049;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,145:5:0 0,6,64:2:0 +17 2455 . C 0 . DP=22;I16=14,8,0,0,776,28212,0,0,1227,70923,0,0,461,10369,0,0;QS=3,0;MQSB=0.715049;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,138:5:0 0,6,65:2:0 +17 2456 . T 0 . DP=24;I16=14,9,0,0,834,30902,0,0,1318,77282,0,0,444,10036,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,168:6:0 0,6,60:2:0 +17 2457 . C 0 . DP=24;I16=15,9,0,0,816,29244,0,0,1347,78123,0,0,478,10924,0,0;QS=3,0;MQSB=0.72325;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,159:6:0 0,6,65:2:0 +17 2458 . A 0 . DP=24;I16=15,9,0,0,869,32555,0,0,1347,78123,0,0,487,11209,0,0;QS=3,0;MQSB=0.72325;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,166:6:0 0,6,65:2:0 +17 2459 . G T, 0 . DP=24;I16=13,9,1,0,822,31186,13,169,1289,76441,29,841,453,10551,17,289;QS=2.92973,0.0702703,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.851535;BQB=1;MQ0F=0 PL:DP:DV 0,45,255,45,255,255:15:0 0,5,138,15,141,144:6:1 0,6,64,6,64,64:2:0 +17 2460 . G 0 . DP=24;I16=14,9,0,0,834,31432,0,0,1318,77282,0,0,477,11065,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,160:6:0 0,6,65:2:0 +17 2461 . A G, 0 . DP=24;I16=14,9,1,0,839,31487,13,169,1318,77282,29,841,489,11521,19,361;QS=2.93401,0.0659898,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.72325;BQB=1;MQ0F=0 PL:DP:DV 0,48,255,48,255,255:16:0 0,5,148,15,151,154:6:1 0,6,67,6,67,67:2:0 +17 2462 . G 0 . DP=25;I16=15,10,0,0,893,33155,0,0,1407,81723,0,0,514,12090,0,0;QS=3,0;MQSB=0.707404;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,165:6:0 0,6,66:2:0 +17 2463 . G T, 0 . DP=25;I16=12,10,1,0,777,28525,14,196,1289,76441,29,841,452,10720,25,625;QS=2.975,0.025,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.825053;BQB=1;MQ0F=0 PL:DP:DV 0,36,255,48,255,255:17:1 0,12,133,12,133,133:4:0 0,6,68,6,68,68:2:0 +17 2464 . C 0 . DP=25;I16=15,10,0,0,904,34194,0,0,1407,81723,0,0,526,12458,0,0;QS=3,0;MQSB=0.707404;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,149:6:0 0,6,67:2:0 +17 2465 . T 0 . DP=25;I16=14,10,0,0,857,32235,0,0,1347,78123,0,0,506,11994,0,0;QS=3,0;MQSB=0.679965;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,163:6:0 0,6,69:2:0 +17 2466 . G 0 . DP=24;I16=14,9,0,0,852,32336,0,0,1318,77282,0,0,509,12025,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,157:6:0 0,6,63:2:0 +17 2467 . A 0 . DP=24;I16=14,9,0,0,829,30725,0,0,1318,77282,0,0,513,12121,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,168:6:0 0,6,67:2:0 +17 2468 . G 0 . DP=24;I16=15,9,0,0,890,34034,0,0,1347,78123,0,0,541,12807,0,0;QS=3,0;MQSB=0.72325;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,169:6:0 0,6,64:2:0 +17 2469 . G 0 . DP=24;I16=15,9,0,0,865,32303,0,0,1347,78123,0,0,544,12882,0,0;QS=3,0;MQSB=0.72325;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,174:6:0 0,6,58:2:0 +17 2470 . G 0 . DP=24;I16=14,9,0,0,829,30785,0,0,1318,77282,0,0,521,12295,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,178:6:0 0,6,58:2:0 +17 2471 . G 0 . DP=24;I16=14,9,0,0,833,31429,0,0,1318,77282,0,0,523,12345,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,170:5:0 0,6,64:2:0 +17 2472 . G 0 . DP=24;I16=13,9,0,0,774,28428,0,0,1289,76441,0,0,499,11733,0,0;QS=3,0;MQSB=0.955854;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,154:5:0 0,6,56:2:0 +17 2473 . A 0 . DP=24;I16=13,9,0,0,775,28137,0,0,1258,73682,0,0,508,12078,0,0;QS=3,0;MQSB=0.834768;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,160:5:0 0,6,63:2:0 +17 2474 . A 0 . DP=25;I16=15,9,0,0,851,31665,0,0,1378,80882,0,0,524,12322,0,0;QS=3,0;MQSB=0.865888;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,160:5:0 0,9,80:3:0 +17 2475 . G 0 . DP=25;I16=15,9,0,0,913,35239,0,0,1378,80882,0,0,525,12323,0,0;QS=3,0;MQSB=0.865888;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,167:5:0 0,9,84:3:0 +17 2476 . G 0 . DP=25;I16=13,9,0,0,776,28584,0,0,1289,76441,0,0,488,11544,0,0;QS=3,0;MQSB=0.955854;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,138:5:0 0,9,82:3:0 +17 2477 . A 0 . DP=25;I16=14,9,0,0,867,34329,0,0,1318,77282,0,0,515,12223,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,178:5:0 0,9,91:3:0 +17 2478 . C 0 . DP=25;I16=14,9,0,0,897,36911,0,0,1318,77282,0,0,517,12289,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,175:5:0 0,9,87:3:0 +17 2479 . T 0 . DP=25;I16=15,9,0,0,921,37957,0,0,1378,80882,0,0,529,12467,0,0;QS=3,0;MQSB=0.865888;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,176:5:0 0,9,97:3:0 +17 2480 . G 0 . DP=25;I16=14,9,0,0,877,35485,0,0,1349,80041,0,0,504,11864,0,0;QS=3,0;MQSB=0.960618;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,176:5:0 0,9,88:3:0 +17 2481 . C 0 . DP=25;I16=13,9,0,0,848,34542,0,0,1289,76441,0,0,496,11838,0,0;QS=3,0;MQSB=0.955854;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,183:5:0 0,9,88:3:0 +17 2482 . T 0 . DP=25;I16=15,9,0,0,905,37331,0,0,1378,80882,0,0,526,12430,0,0;QS=3,0;MQSB=0.865888;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,178:5:0 0,9,96:3:0 +17 2483 . T 0 . DP=25;I16=14,9,0,0,879,36187,0,0,1318,77282,0,0,517,12311,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,180:5:0 0,9,89:3:0 +17 2484 . G 0 . DP=25;I16=14,9,0,0,884,35142,0,0,1349,80041,0,0,494,11604,0,0;QS=3,0;MQSB=0.960618;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,174:5:0 0,9,84:3:0 +17 2485 . A T, 0 . DP=25;I16=14,9,1,0,891,36757,17,289,1349,80041,29,841,490,11502,25,625;QS=2.96926,0.0307414,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.865888;BQB=1;MQ0F=0 PL:DP:DV 0,31,255,45,255,255:16:1 0,15,193,15,193,193:5:0 0,9,93,9,93,93:3:0 +17 2486 . G 0 . DP=25;I16=15,9,0,0,898,36230,0,0,1378,80882,0,0,511,12041,0,0;QS=3,0;MQSB=0.865888;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,153:5:0 0,9,90:3:0 +17 2487 . C 0 . DP=25;I16=14,9,0,0,793,30695,0,0,1349,80041,0,0,482,11346,0,0;QS=3,0;MQSB=0.960618;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,175:5:0 0,9,91:3:0 +17 2488 . C 0 . DP=25;I16=13,9,0,0,841,34597,0,0,1289,76441,0,0,457,10841,0,0;QS=3,0;MQSB=0.955854;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,174:5:0 0,9,93:3:0 +17 2489 . C 0 . DP=23;I16=11,9,0,0,801,34227,0,0,1169,69241,0,0,454,10788,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,187:5:0 0,9,93:3:0 +17 2490 . A 0 . DP=23;I16=11,10,0,0,818,34642,0,0,1229,72841,0,0,451,10695,0,0;QS=3,0;MQSB=0.939898;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,175:5:0 0,12,128:4:0 +17 2491 . G 0 . DP=23;I16=12,10,0,0,845,35143,0,0,1258,73682,0,0,471,11097,0,0;QS=3,0;MQSB=0.804615;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,178:5:0 0,12,121:4:0 +17 2492 . G A, 0 . DP=23;I16=11,10,1,0,845,36207,16,256,1229,72841,29,841,446,10494,21,441;QS=2.96708,0.0329218,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.804615;BQB=1;MQ0F=0 PL:DP:DV 0,22,255,36,255,255:13:1 0,15,187,15,187,187:5:0 0,12,124,12,124,124:4:0 +17 2493 . A G, 0 . DP=23;I16=11,10,1,0,855,37007,13,169,1229,72841,29,841,442,10340,20,400;QS=2.97269,0.0273109,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.804615;BQB=1;MQ0F=0 PL:DP:DV 0,25,255,36,255,255:13:1 0,15,191,15,191,191:5:0 0,12,127,12,127,127:4:0 +17 2494 . G 0 . DP=23;I16=11,10,0,0,802,32720,0,0,1229,72841,0,0,437,10153,0,0;QS=3,0;MQSB=0.939898;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,179:5:0 0,12,118:4:0 +17 2495 . T 0 . DP=23;I16=10,10,0,0,737,29861,0,0,1138,66482,0,0,413,9513,0,0;QS=3,0;MQSB=0.751477;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,172:5:0 0,12,113:4:0 +17 2496 . T 0 . DP=23;I16=12,10,0,0,815,32793,0,0,1258,73682,0,0,442,10026,0,0;QS=3,0;MQSB=0.804615;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,183:5:0 0,12,123:4:0 +17 2497 . T 0 . DP=22;I16=12,9,0,0,807,33723,0,0,1198,70082,0,0,436,9814,0,0;QS=3,0;MQSB=0.815018;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,177:5:0 0,12,131:4:0 +17 2498 . G 0 . DP=22;I16=12,9,0,0,808,33264,0,0,1198,70082,0,0,430,9622,0,0;QS=3,0;MQSB=0.815018;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,173:5:0 0,12,127:4:0 +17 2499 . A 0 . DP=22;I16=12,9,0,0,847,36803,0,0,1198,70082,0,0,424,9450,0,0;QS=3,0;MQSB=0.815018;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,185:5:0 0,12,133:4:0 +17 2500 . G 0 . DP=22;I16=11,9,0,0,772,32546,0,0,1169,69241,0,0,404,9078,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,168:5:0 0,12,129:4:0 +17 2501 . G 0 . DP=22;I16=11,8,0,0,768,33120,0,0,1109,65641,0,0,373,8293,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,146:4:0 0,12,118:4:0 +17 2502 . C 0 . DP=22;I16=12,8,0,0,798,33902,0,0,1138,66482,0,0,378,8270,0,0;QS=3,0;MQSB=0.826565;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,155:4:0 0,12,125:4:0 +17 2503 . T 0 . DP=22;I16=12,9,0,0,851,36841,0,0,1198,70082,0,0,396,8746,0,0;QS=3,0;MQSB=0.815018;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,180:5:0 0,12,139:4:0 +17 2504 . G 0 . DP=22;I16=12,9,0,0,787,31955,0,0,1198,70082,0,0,389,8615,0,0;QS=3,0;MQSB=0.815018;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,171:5:0 0,12,129:4:0 +17 2505 . C 0 . DP=21;I16=11,9,0,0,792,33440,0,0,1138,66482,0,0,383,8501,0,0;QS=3,0;MQSB=0.791547;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,169:5:0 0,12,132:4:0 +17 2506 . T 0 . DP=22;I16=11,10,0,0,798,32868,0,0,1198,70082,0,0,376,8354,0,0;QS=3,0;MQSB=0.780412;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,175:5:0 0,15,169:5:0 +17 2507 . G 0 . DP=21;I16=9,10,0,0,716,30074,0,0,1109,65641,0,0,365,8189,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,15,163:5:0 0,15,153:5:0 +17 2508 . T 0 . DP=21;I16=9,10,0,0,724,30396,0,0,1109,65641,0,0,361,8089,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,15,158:5:0 0,15,162:5:0 +17 2509 . G T, 0 . DP=21;I16=8,10,1,0,710,30408,35,1225,1049,62041,60,3600,330,7282,25,625;QS=2.80663,0.19337,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.920044;BQB=1;MQ0F=0 PL:DP:DV 0,27,253,27,253,253:9:0 20,0,122,32,125,150:5:1 0,15,163,15,163,163:5:0 +17 2510 . A 0 . DP=21;I16=10,10,0,0,778,33128,0,0,1138,66482,0,0,352,7754,0,0;QS=3,0;MQSB=0.751477;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,174:5:0 0,15,161:5:0 +17 2511 . G 0 . DP=21;I16=10,10,0,0,771,32165,0,0,1138,66482,0,0,344,7558,0,0;QS=3,0;MQSB=0.751477;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,161:5:0 0,15,159:5:0 +17 2512 . C 0 . DP=21;I16=10,10,0,0,790,33406,0,0,1138,66482,0,0,336,7386,0,0;QS=3,0;MQSB=0.751477;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,175:5:0 0,15,160:5:0 +17 2513 . T 0 . DP=21;I16=10,10,0,0,755,31503,0,0,1138,66482,0,0,327,7189,0,0;QS=3,0;MQSB=0.751477;MQ0F=0 PL:DP:DV 0,30,246:10:0 0,15,180:5:0 0,15,156:5:0 +17 2514 . G 0 . DP=20;I16=9,10,0,0,702,28002,0,0,1109,65641,0,0,319,7017,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,15,171:5:0 0,15,155:5:0 +17 2515 . T 0 . DP=19;I16=8,10,0,0,642,25888,0,0,1049,62041,0,0,312,6868,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,24,182:8:0 0,15,172:5:0 0,15,141:5:0 +17 2516 . G 0 . DP=19;I16=8,10,0,0,685,28155,0,0,1049,62041,0,0,303,6641,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,24,211:8:0 0,15,175:5:0 0,15,147:5:0 +17 2517 . A 0 . DP=18;I16=8,9,0,0,660,27600,0,0,989,58441,0,0,295,6435,0,0;QS=3,0;MQSB=0.91051;MQ0F=0 PL:DP:DV 0,24,215:8:0 0,12,139:4:0 0,15,161:5:0 +17 2518 . T 0 . DP=17;I16=6,9,0,0,611,26911,0,0,900,54000,0,0,273,6023,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,188:7:0 0,12,144:4:0 0,12,146:4:0 +17 2519 . C 0 . DP=16;I16=7,8,0,0,531,20111,0,0,900,54000,0,0,282,6078,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,175:7:0 0,12,141:4:0 0,12,125:4:0 +17 2520 . G 0 . DP=15;I16=6,8,0,0,501,19731,0,0,840,50400,0,0,277,5923,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,187:7:0 0,12,129:4:0 0,9,101:3:0 +17 2521 . C 0 . DP=15;I16=6,8,0,0,583,25777,0,0,840,50400,0,0,272,5782,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,214:7:0 0,12,149:4:0 0,9,111:3:0 +17 2522 . A 0 . DP=16;I16=6,8,0,0,516,20930,0,0,840,50400,0,0,266,5606,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,173:7:0 0,12,139:4:0 0,9,114:3:0 +17 2523 . T 0 . DP=16;I16=6,9,0,0,588,25538,0,0,900,54000,0,0,270,5546,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,207:7:0 0,15,157:5:0 0,9,117:3:0 +17 2524 . C 0 . DP=16;I16=5,9,0,0,548,23502,0,0,840,50400,0,0,256,5342,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,182:6:0 0,15,156:5:0 0,9,112:3:0 +17 2525 . A C, 0 . DP=17;I16=6,9,0,1,550,23138,28,784,900,54000,60,3600,248,5174,12,144;QS=2.86,0.14,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,24,168,24,168,168:8:0 13,0,138,25,141,159:5:1 0,9,117,9,117,117:3:0 +17 2526 . C 0 . DP=18;I16=6,11,0,0,677,28649,0,0,1020,61200,0,0,256,5232,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,229:9:0 0,15,183:5:0 0,9,113:3:0 +17 2527 . T 0 . DP=18;I16=6,11,0,0,674,29286,0,0,1020,61200,0,0,252,5118,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,217:9:0 0,15,183:5:0 0,9,119:3:0 +17 2528 . G 0 . DP=18;I16=6,11,0,0,701,30729,0,0,1020,61200,0,0,248,5028,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,234:9:0 0,15,184:5:0 0,9,119:3:0 +17 2529 . C 0 . DP=18;I16=6,11,0,0,676,28974,0,0,1020,61200,0,0,244,4962,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,15,175:5:0 0,9,117:3:0 +17 2530 . A 0 . DP=18;I16=6,10,0,0,624,26620,0,0,960,57600,0,0,223,4631,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,209:9:0 0,12,153:4:0 0,9,116:3:0 +17 2531 . T 0 . DP=17;I16=6,10,0,0,641,27911,0,0,960,57600,0,0,236,4852,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,210:8:0 0,15,175:5:0 0,9,122:3:0 +17 2532 . T 0 . DP=17;I16=6,10,0,0,634,27460,0,0,960,57600,0,0,230,4708,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,212:8:0 0,15,173:5:0 0,9,117:3:0 +17 2533 . C 0 . DP=18;I16=6,11,0,0,614,24196,0,0,1020,61200,0,0,224,4588,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,212:9:0 0,15,159:5:0 0,9,104:3:0 +17 2534 . C 0 . DP=16;I16=5,10,0,0,595,25141,0,0,900,54000,0,0,221,4491,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,202:8:0 0,12,144:4:0 0,9,110:3:0 +17 2535 . A 0 . DP=16;I16=5,10,0,0,617,27711,0,0,900,54000,0,0,218,4416,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,204:8:0 0,12,136:4:0 0,9,123:3:0 +17 2536 . G 0 . DP=15;I16=4,10,0,0,543,23023,0,0,840,50400,0,0,216,4362,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,195:8:0 0,9,102:3:0 0,9,117:3:0 +17 2537 . C 0 . DP=15;I16=4,10,0,0,555,24075,0,0,840,50400,0,0,213,4279,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,195:8:0 0,9,113:3:0 0,9,115:3:0 +17 2538 . C 0 . DP=15;I16=5,9,0,0,510,21070,0,0,840,50400,0,0,211,4217,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,157:7:0 0,9,129:3:0 0,12,126:4:0 +17 2539 . C 0 . DP=15;I16=5,9,0,0,464,16896,0,0,840,50400,0,0,209,4125,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,146:7:0 0,9,122:3:0 0,12,111:4:0 +17 2540 . G 0 . DP=16;I16=6,9,0,0,548,21860,0,0,900,54000,0,0,207,4053,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,189:7:0 0,12,139:4:0 0,12,110:4:0 +17 2541 . G 0 . DP=15;I16=5,9,0,0,535,22527,0,0,840,50400,0,0,207,4001,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,170:7:0 0,9,117:3:0 0,12,140:4:0 +17 2542 . T 0 . DP=15;I16=4,9,0,0,527,23207,0,0,780,46800,0,0,203,3953,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,183:7:0 0,9,125:3:0 0,9,109:3:0 +17 2543 . G 0 . DP=15;I16=5,9,0,0,540,23004,0,0,840,50400,0,0,207,3957,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,196:7:0 0,9,117:3:0 0,12,117:4:0 +17 2544 . A 0 . DP=16;I16=6,9,0,0,569,24139,0,0,900,54000,0,0,207,3965,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,202:8:0 0,9,119:3:0 0,12,132:4:0 +17 2545 . C 0 . DP=16;I16=6,9,0,0,583,24657,0,0,900,54000,0,0,208,3994,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,217:8:0 0,9,118:3:0 0,12,130:4:0 +17 2546 . A 0 . DP=16;I16=6,9,0,0,608,27290,0,0,900,54000,0,0,209,4045,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,206:8:0 0,9,133:3:0 0,12,144:4:0 +17 2547 . G 0 . DP=16;I16=6,9,0,0,597,26215,0,0,900,54000,0,0,211,4117,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,191:7:0 0,9,131:3:0 0,15,150:5:0 +17 2548 . A 0 . DP=16;I16=6,9,0,0,632,28806,0,0,900,54000,0,0,214,4210,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,196:7:0 0,9,131:3:0 0,15,171:5:0 +17 2549 . G 0 . DP=16;I16=6,9,0,0,594,25254,0,0,900,54000,0,0,217,4325,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,180:7:0 0,9,132:3:0 0,15,160:5:0 +17 2550 . T 0 . DP=16;I16=6,9,0,0,572,24134,0,0,900,54000,0,0,219,4413,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,182:7:0 0,9,122:3:0 0,15,148:5:0 +17 2551 . G 0 . DP=16;I16=6,9,0,0,578,24606,0,0,900,54000,0,0,220,4474,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,181:7:0 0,9,131:3:0 0,15,151:5:0 +17 2552 . A 0 . DP=15;I16=6,8,0,0,585,26419,0,0,840,50400,0,0,221,4505,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,178:6:0 0,9,129:3:0 0,15,168:5:0 +17 2553 . G 0 . DP=15;I16=6,8,0,0,528,21944,0,0,840,50400,0,0,222,4554,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,170:6:0 0,9,117:3:0 0,15,142:5:0 +17 2554 . T 0 . DP=15;I16=6,8,0,0,543,23015,0,0,840,50400,0,0,223,4621,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,156:6:0 0,9,129:3:0 0,15,160:5:0 +17 2555 . C 0 . DP=15;I16=6,8,0,0,566,24416,0,0,840,50400,0,0,224,4706,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,173:6:0 0,9,131:3:0 0,15,159:5:0 +17 2556 . A 0 . DP=14;I16=6,7,0,0,487,20095,0,0,780,46800,0,0,226,4808,0,0;QS=3,0;MQSB=0.961166;MQ0F=0 PL:DP:DV 0,15,141:5:0 0,9,125:3:0 0,15,146:5:0 +17 2557 . C 0 . DP=13;I16=5,8,0,0,471,17481,0,0,780,46800,0,0,249,5325,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,161:5:0 0,9,96:3:0 0,15,151:5:0 +17 2558 . T 0 . DP=14;I16=5,9,0,0,535,20597,0,0,840,50400,0,0,251,5417,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,173:6:0 0,9,99:3:0 0,15,174:5:0 +17 2559 . G 0 . DP=14;I16=5,9,0,0,509,18693,0,0,840,50400,0,0,253,5475,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,172:6:0 0,9,98:3:0 0,15,156:5:0 +17 2560 . T 0 . DP=14;I16=5,9,0,0,489,17587,0,0,840,50400,0,0,255,5549,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,160:6:0 0,9,106:3:0 0,15,144:5:0 +17 2561 . C 0 . DP=14;I16=5,9,0,0,489,17477,0,0,840,50400,0,0,257,5639,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,164:6:0 0,9,96:3:0 0,15,153:5:0 +17 2562 . T 0 . DP=13;I16=5,8,0,0,460,17016,0,0,780,46800,0,0,260,5744,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,139:5:0 0,9,99:3:0 0,15,167:5:0 +17 2563 . C 0 . DP=14;I16=5,8,0,0,433,15133,0,0,780,46800,0,0,263,5863,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,149:5:0 0,9,83:3:0 0,15,142:5:0 +17 2564 . A G, 0 . DP=15;I16=1,4,4,5,174,6124,316,11352,300,18000,540,32400,61,1311,184,4034;QS=0.988263,2.01174,0;VDB=0.690812;SGB=-3.20711;RPB=0.197899;MQB=1;MQSB=1;BQB=0.965069;MQ0F=0 PL:DP:DV 88,0,78,98,87,171:6:3 57,0,56,63,62,117:4:2 124,12,0,124,12,124:4:4 +17 2565 . A 0 . DP=15;I16=6,9,0,0,562,21216,0,0,900,54000,0,0,274,6076,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,178:6:0 0,12,134:4:0 0,15,166:5:0 +17 2566 . A 0 . DP=15;I16=6,9,0,0,545,20019,0,0,900,54000,0,0,276,6098,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,181:6:0 0,12,120:4:0 0,15,162:5:0 +17 2567 . A 0 . DP=16;I16=7,9,0,0,580,21342,0,0,960,57600,0,0,278,6136,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,177:6:0 0,15,151:5:0 0,15,166:5:0 +17 2568 . A 0 . DP=16;I16=7,8,0,0,555,20795,0,0,900,54000,0,0,256,5566,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,180:6:0 0,12,132:4:0 0,15,167:5:0 +17 2569 . A 0 . DP=17;I16=7,10,0,0,661,25943,0,0,1020,61200,0,0,284,6264,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,213:7:0 0,15,163:5:0 0,15,172:5:0 +17 2570 . G 0 . DP=18;I16=8,10,0,0,664,24968,0,0,1080,64800,0,0,287,6305,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,213:7:0 0,15,152:5:0 0,18,176:6:0 +17 2571 . A 0 . DP=18;I16=8,10,0,0,618,21870,0,0,1080,64800,0,0,291,6365,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,195:7:0 0,15,155:5:0 0,18,155:6:0 +17 2572 . A 0 . DP=18;I16=8,10,0,0,631,22829,0,0,1080,64800,0,0,295,6445,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,194:7:0 0,15,150:5:0 0,18,173:6:0 +17 2573 . A 0 . DP=18;I16=8,10,0,0,690,26830,0,0,1080,64800,0,0,298,6494,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,210:7:0 0,15,170:5:0 0,18,183:6:0 +17 2574 . G 0 . DP=18;I16=8,10,0,0,664,24884,0,0,1080,64800,0,0,301,6561,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,211:7:0 0,15,152:5:0 0,18,176:6:0 +17 2575 . G 0 . DP=18;I16=8,10,0,0,642,23904,0,0,1080,64800,0,0,305,6645,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,242:8:0 0,15,145:5:0 0,15,140:5:0 +17 2576 . A 0 . DP=18;I16=7,10,0,0,595,21311,0,0,1020,61200,0,0,285,6121,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,210:8:0 0,15,153:5:0 0,12,131:4:0 +17 2577 . A 0 . DP=19;I16=8,10,0,0,682,26398,0,0,1080,64800,0,0,290,6240,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,244:8:0 0,15,161:5:0 0,15,155:5:0 +17 2578 . G 0 . DP=18;I16=9,9,0,0,643,24115,0,0,1080,64800,0,0,322,7002,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,249:8:0 0,12,114:4:0 0,18,161:6:0 +17 2579 . A 0 . DP=18;I16=9,8,0,0,634,23870,0,0,1020,61200,0,0,304,6532,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,229:8:0 0,9,110:3:0 0,18,176:6:0 +17 2580 . A 0 . DP=18;I16=9,9,0,0,629,22593,0,0,1080,64800,0,0,336,7330,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,223:8:0 0,12,117:4:0 0,18,169:6:0 +17 2581 . A 0 . DP=19;I16=10,9,0,0,691,25669,0,0,1140,68400,0,0,343,7521,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,12,133:4:0 0,18,166:6:0 +17 2582 . T 0 . DP=19;I16=10,9,0,0,674,24218,0,0,1140,68400,0,0,350,7682,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,235:9:0 0,12,138:4:0 0,18,168:6:0 +17 2583 . A 0 . DP=19;I16=10,9,0,0,693,25465,0,0,1140,68400,0,0,357,7865,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,247:9:0 0,12,126:4:0 0,18,178:6:0 +17 2584 . A 0 . DP=19;I16=10,9,0,0,702,26340,0,0,1140,68400,0,0,363,8019,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,243:9:0 0,12,134:4:0 0,18,187:6:0 +17 2585 . A 0 . DP=19;I16=9,9,0,0,690,26700,0,0,1080,64800,0,0,350,7818,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,250:9:0 0,9,114:3:0 0,18,190:6:0 +17 2586 . G 0 . DP=19;I16=10,9,0,0,714,27314,0,0,1140,68400,0,0,373,8283,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,12,127:4:0 0,18,176:6:0 +17 2587 . A 0 . DP=20;I16=9,9,0,0,665,24781,0,0,1049,62041,0,0,343,7717,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,137:4:0 0,12,136:4:0 +17 2588 . A 0 . DP=21;I16=12,9,0,0,737,26531,0,0,1229,72841,0,0,384,8620,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,138:4:0 0,18,162:6:0 +17 2589 . A 0 . DP=22;I16=13,9,0,0,780,28412,0,0,1289,76441,0,0,390,8770,0,0;QS=3,0;MQSB=0.955854;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,142:4:0 0,18,170:6:0 +17 2590 . A 0 . DP=22;I16=13,9,0,0,774,28352,0,0,1289,76441,0,0,396,8894,0,0;QS=3,0;MQSB=0.955854;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,135:4:0 0,18,160:6:0 +17 2591 . C 0 . DP=21;I16=13,8,0,0,765,28617,0,0,1229,72841,0,0,403,9041,0,0;QS=3,0;MQSB=0.95891;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,136:4:0 0,15,136:5:0 +17 2592 . A 0 . DP=21;I16=13,8,0,0,763,28325,0,0,1229,72841,0,0,410,9210,0,0;QS=3,0;MQSB=0.95891;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,140:4:0 0,15,139:5:0 +17 2593 . A 0 . DP=21;I16=13,8,0,0,754,27888,0,0,1229,72841,0,0,416,9350,0,0;QS=3,0;MQSB=0.95891;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,141:4:0 0,15,147:5:0 +17 2594 . A 0 . DP=21;I16=13,8,0,0,775,29179,0,0,1229,72841,0,0,422,9510,0,0;QS=3,0;MQSB=0.95891;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,130:4:0 0,15,153:5:0 +17 2595 . T 0 . DP=22;I16=14,8,0,0,766,27472,0,0,1289,76441,0,0,427,9639,0,0;QS=3,0;MQSB=0.963419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,119:4:0 0,15,143:5:0 +17 2596 . A 0 . DP=22;I16=13,8,0,0,751,27409,0,0,1229,72841,0,0,407,9111,0,0;QS=3,0;MQSB=0.95891;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,123:4:0 0,12,129:4:0 +17 2597 . A 0 . DP=22;I16=14,8,0,0,811,30147,0,0,1289,76441,0,0,437,9851,0,0;QS=3,0;MQSB=0.963419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,145:4:0 0,15,145:5:0 +17 2598 . A 0 . DP=22;I16=14,8,0,0,817,30915,0,0,1289,76441,0,0,442,9984,0,0;QS=3,0;MQSB=0.963419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,136:4:0 0,15,159:5:0 +17 2599 . A 0 . DP=22;I16=14,8,0,0,800,29912,0,0,1289,76441,0,0,447,10135,0,0;QS=3,0;MQSB=0.963419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,126:4:0 0,15,150:5:0 +17 2600 . A 0 . DP=22;I16=14,8,0,0,784,29138,0,0,1289,76441,0,0,451,10255,0,0;QS=3,0;MQSB=0.963419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,113:4:0 0,15,150:5:0 +17 2601 . T 0 . DP=22;I16=14,8,0,0,770,27820,0,0,1289,76441,0,0,454,10344,0,0;QS=3,0;MQSB=0.963419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,118:4:0 0,15,142:5:0 +17 2602 . A 0 . DP=23;I16=15,8,0,0,825,29971,0,0,1349,80041,0,0,457,10451,0,0;QS=3,0;MQSB=0.967216;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,143:4:0 0,18,154:6:0 +17 2603 . A 0 . DP=23;I16=15,8,0,0,862,32840,0,0,1349,80041,0,0,460,10526,0,0;QS=3,0;MQSB=0.967216;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,138:4:0 0,18,172:6:0 +17 2604 . T 0 . DP=23;I16=15,8,0,0,822,29902,0,0,1349,80041,0,0,463,10619,0,0;QS=3,0;MQSB=0.967216;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,129:4:0 0,18,154:6:0 +17 2605 . A 0 . DP=23;I16=14,8,0,0,845,32617,0,0,1289,76441,0,0,441,10105,0,0;QS=3,0;MQSB=0.963419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,143:4:0 0,15,157:5:0 +17 2606 . G 0 . DP=23;I16=14,8,0,0,812,30796,0,0,1289,76441,0,0,444,10234,0,0;QS=3,0;MQSB=0.963419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,129:4:0 0,15,142:5:0 +17 2607 . T 0 . DP=22;I16=15,7,0,0,782,28440,0,0,1289,76441,0,0,472,10954,0,0;QS=3,0;MQSB=0.970024;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,119:4:0 0,15,132:5:0 +17 2608 . G 0 . DP=22;I16=15,7,0,0,851,33169,0,0,1289,76441,0,0,474,11014,0,0;QS=3,0;MQSB=0.970024;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,132:4:0 0,15,127:5:0 +17 2609 . C 0 . DP=22;I16=15,7,0,0,796,29454,0,0,1289,76441,0,0,475,11041,0,0;QS=3,0;MQSB=0.970024;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,137:4:0 0,15,124:5:0 +17 2610 . A 0 . DP=22;I16=15,7,0,0,830,31684,0,0,1289,76441,0,0,476,11086,0,0;QS=3,0;MQSB=0.970024;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,146:4:0 0,15,121:5:0 +17 2611 . G 0 . DP=22;I16=15,7,0,0,824,32048,0,0,1289,76441,0,0,477,11149,0,0;QS=3,0;MQSB=0.970024;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,129:4:0 0,15,122:5:0 +17 2612 . A 0 . DP=22;I16=14,7,0,0,771,29035,0,0,1229,72841,0,0,453,10605,0,0;QS=3,0;MQSB=0.966484;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,130:4:0 0,12,117:4:0 +17 2613 . C 0 . DP=22;I16=15,7,0,0,832,31926,0,0,1289,76441,0,0,478,11278,0,0;QS=3,0;MQSB=0.970024;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,138:4:0 0,15,120:5:0 +17 2614 . A 0 . DP=21;I16=15,6,0,0,791,30065,0,0,1229,72841,0,0,477,11241,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,110:3:0 0,15,140:5:0 +17 2615 . A 0 . DP=21;I16=15,6,0,0,777,29101,0,0,1229,72841,0,0,475,11167,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,99:3:0 0,15,142:5:0 +17 2616 . A 0 . DP=21;I16=15,6,0,0,734,26922,0,0,1229,72841,0,0,472,11056,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,90:3:0 0,15,144:5:0 +17 2617 . A 0 . DP=21;I16=15,6,0,0,810,31654,0,0,1229,72841,0,0,469,10959,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,95:3:0 0,15,140:5:0 +17 2618 . G 0 . DP=23;I16=16,6,0,0,863,34219,0,0,1289,76441,0,0,441,10251,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,74:2:0 0,15,132:5:0 +17 2619 . G 0 . DP=23;I16=16,6,0,0,807,30109,0,0,1289,76441,0,0,439,10135,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,66:2:0 0,15,127:5:0 +17 2620 . C 0 . DP=23;I16=16,7,0,0,780,28242,0,0,1349,80041,0,0,462,10664,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,87:3:0 0,15,115:5:0 +17 2621 . C 0 . DP=23;I16=16,7,0,0,860,32944,0,0,1349,80041,0,0,459,10537,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,112:3:0 0,15,124:5:0 +17 2622 . T 0 . DP=24;I16=17,7,0,0,908,35474,0,0,1409,83641,0,0,456,10428,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,115:3:0 0,15,134:5:0 +17 2623 . T 0 . DP=24;I16=17,7,0,0,850,30978,0,0,1409,83641,0,0,453,10289,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,114:3:0 0,15,129:5:0 +17 2624 . G 0 . DP=24;I16=17,7,0,0,882,33332,0,0,1409,83641,0,0,450,10172,0,0;QS=3,0;MQSB=0.975597;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,101:3:0 0,15,133:5:0 +17 2625 . A 0 . DP=23;I16=17,6,0,0,855,32593,0,0,1349,80041,0,0,448,10076,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,114:3:0 0,15,135:5:0 +17 2626 . C 0 . DP=23;I16=17,6,0,0,847,31625,0,0,1349,80041,0,0,446,10000,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,100:3:0 0,15,122:5:0 +17 2627 . C 0 . DP=23;I16=17,6,0,0,863,32865,0,0,1349,80041,0,0,444,9944,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,104:3:0 0,15,129:5:0 +17 2628 . C 0 . DP=24;I16=17,6,0,0,793,28559,0,0,1349,80041,0,0,431,9757,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,95:3:0 0,15,127:5:0 +17 2629 . A 0 . DP=24;I16=18,6,0,0,893,33537,0,0,1409,83641,0,0,439,9789,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,101:3:0 0,18,148:6:0 +17 2630 . T 0 . DP=24;I16=17,6,0,0,836,31094,0,0,1380,82800,0,0,412,9116,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,112:3:0 0,18,140:6:0 +17 2631 . C 0 . DP=24;I16=18,6,0,0,900,34378,0,0,1409,83641,0,0,435,9713,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,104:3:0 0,18,142:6:0 +17 2632 . T 0 . DP=24;I16=18,6,0,0,937,37097,0,0,1409,83641,0,0,433,9705,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,113:3:0 0,18,164:6:0 +17 2633 . A 0 . DP=23;I16=18,5,0,0,801,28913,0,0,1349,80041,0,0,431,9667,0,0;QS=3,0;MQSB=0.982789;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,95:3:0 0,18,148:6:0 +17 2634 . G 0 . DP=23;I16=19,3,0,0,861,34125,0,0,1289,76441,0,0,405,9023,0,0;QS=3,0;MQSB=0.989755;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,74:2:0 0,18,149:6:0 +17 2635 . C 0 . DP=23;I16=19,4,0,0,848,32154,0,0,1349,80041,0,0,429,9599,0,0;QS=3,0;MQSB=0.986928;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,107:3:0 0,18,148:6:0 +17 2636 . T 0 . DP=24;I16=19,4,0,0,871,33973,0,0,1349,80041,0,0,428,9572,0,0;QS=3,0;MQSB=0.986928;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,98:3:0 0,18,160:6:0 +17 2637 . T 0 . DP=24;I16=19,5,0,0,871,32073,0,0,1409,83641,0,0,428,9568,0,0;QS=3,0;MQSB=0.984335;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,111:3:0 0,18,144:6:0 +17 2638 . T 0 . DP=24;I16=19,5,0,0,821,28851,0,0,1409,83641,0,0,428,9588,0,0;QS=3,0;MQSB=0.984335;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,103:3:0 0,18,135:6:0 +17 2639 . G 0 . DP=24;I16=18,6,0,0,842,30840,0,0,1409,83641,0,0,428,9582,0,0;QS=3,0;MQSB=0.980199;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,106:3:0 0,15,125:5:0 +17 2640 . G 0 . DP=24;I16=17,6,0,0,749,25957,0,0,1380,82800,0,0,404,8976,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,84:3:0 0,15,117:5:0 +17 2641 . C 0 . DP=23;I16=17,6,0,0,834,31792,0,0,1349,80041,0,0,431,9645,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,61:2:0 0,15,129:5:0 +17 2642 . C 0 . DP=23;I16=17,6,0,0,809,30033,0,0,1349,80041,0,0,433,9713,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,58:2:0 0,15,131:5:0 +17 2643 . C 0 . DP=23;I16=17,6,0,0,856,33004,0,0,1349,80041,0,0,434,9756,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,57:2:0 0,15,133:5:0 +17 2644 . T 0 . DP=22;I16=16,5,0,0,805,31419,0,0,1229,72841,0,0,428,9648,0,0;QS=3,0;MQSB=0.978919;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,73:2:0 0,15,143:5:0 +17 2645 . C 0 . DP=22;I16=15,6,0,0,823,32499,0,0,1229,72841,0,0,415,9323,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,78:2:0 0,12,122:4:0 +17 2646 . A 0 . DP=22;I16=16,6,0,0,826,31566,0,0,1289,76441,0,0,430,9524,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,79:2:0 0,15,129:5:0 +17 2647 . G 0 . DP=22;I16=16,6,0,0,803,30643,0,0,1289,76441,0,0,428,9460,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,77:2:0 0,15,129:5:0 +17 2648 . C 0 . DP=21;I16=15,6,0,0,811,31709,0,0,1229,72841,0,0,426,9368,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,80:2:0 0,12,118:4:0 +17 2649 . A 0 . DP=23;I16=16,6,0,0,789,29215,0,0,1258,73682,0,0,414,9196,0,0;QS=3,0;MQSB=0.934321;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,93:3:0 0,12,105:4:0 +17 2650 . T 0 . DP=23;I16=16,7,0,0,856,32340,0,0,1318,77282,0,0,423,9197,0,0;QS=3,0;MQSB=0.955805;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,103:3:0 0,12,118:4:0 +17 2651 . C 0 . DP=23;I16=16,7,0,0,871,33599,0,0,1318,77282,0,0,422,9124,0,0;QS=3,0;MQSB=0.955805;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,95:3:0 0,12,121:4:0 +17 2652 . A 0 . DP=23;I16=16,7,0,0,820,30324,0,0,1318,77282,0,0,421,9077,0,0;QS=3,0;MQSB=0.955805;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,87:3:0 0,12,126:4:0 +17 2653 . A 0 . DP=23;I16=15,6,0,0,759,28489,0,0,1198,70082,0,0,389,8395,0,0;QS=3,0;MQSB=0.940481;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,73:2:0 0,9,109:3:0 +17 2654 . C 0 . DP=23;I16=16,7,0,0,836,31006,0,0,1318,77282,0,0,393,8385,0,0;QS=3,0;MQSB=0.955805;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,88:3:0 0,9,99:3:0 +17 2655 . C 0 . DP=23;I16=16,7,0,0,774,27190,0,0,1318,77282,0,0,392,8364,0,0;QS=3,0;MQSB=0.955805;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,83:3:0 0,9,95:3:0 +17 2656 . G 0 . DP=24;I16=17,7,0,0,781,25689,0,0,1378,80882,0,0,390,8320,0,0;QS=3,0;MQSB=0.95083;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,116:4:0 0,9,74:3:0 +17 2657 . C 0 . DP=24;I16=17,6,0,0,871,33435,0,0,1349,80041,0,0,381,8241,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,98:3:0 0,9,99:3:0 +17 2658 . T 0 . DP=23;I16=17,6,0,0,897,35255,0,0,1318,77282,0,0,389,8319,0,0;QS=3,0;MQSB=0.92854;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,133:4:0 0,9,107:3:0 +17 2659 . A 0 . DP=23;I16=17,6,0,0,817,29729,0,0,1318,77282,0,0,389,8361,0,0;QS=3,0;MQSB=0.92854;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,120:4:0 0,9,93:3:0 +17 2660 . G 0 . DP=23;I16=17,6,0,0,900,35462,0,0,1318,77282,0,0,389,8379,0,0;QS=3,0;MQSB=0.92854;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,126:4:0 0,9,94:3:0 +17 2661 . A 0 . DP=24;I16=18,6,0,0,871,32185,0,0,1378,80882,0,0,390,8422,0,0;QS=3,0;MQSB=0.923116;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,127:4:0 0,9,104:3:0 +17 2662 . T 0 . DP=24;I16=17,6,0,0,836,30812,0,0,1349,80041,0,0,366,7816,0,0;QS=3,0;MQSB=0.83771;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,122:4:0 0,9,99:3:0 +17 2663 . A 0 . DP=24;I16=17,6,0,0,827,30583,0,0,1318,77282,0,0,389,8341,0,0;QS=3,0;MQSB=0.92854;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,104:4:0 0,9,101:3:0 +17 2664 . C 0 . DP=23;I16=17,6,0,0,787,28083,0,0,1318,77282,0,0,388,8270,0,0;QS=3,0;MQSB=0.92854;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,107:4:0 0,9,91:3:0 +17 2665 . G 0 . DP=23;I16=17,6,0,0,728,23290,0,0,1318,77282,0,0,386,8178,0,0;QS=3,0;MQSB=0.92854;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,112:4:0 0,9,78:3:0 +17 2666 . T 0 . DP=23;I16=17,5,0,0,799,29273,0,0,1289,76441,0,0,367,7825,0,0;QS=3,0;MQSB=0.981001;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,105:3:0 0,9,94:3:0 +17 2667 . C 0 . DP=23;I16=16,5,0,0,792,30190,0,0,1260,75600,0,0,345,7393,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,96:3:0 0,9,98:3:0 +17 2668 . C 0 . DP=24;I16=18,6,0,0,832,29692,0,0,1378,80882,0,0,381,8069,0,0;QS=3,0;MQSB=0.923116;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,107:4:0 0,9,95:3:0 +17 2669 . C 0 . DP=23;I16=18,5,0,0,829,30953,0,0,1318,77282,0,0,383,8087,0,0;QS=3,0;MQSB=0.889264;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,120:4:0 0,9,88:3:0 +17 2670 . T 0 . DP=23;I16=17,5,0,0,841,32669,0,0,1289,76441,0,0,368,7828,0,0;QS=3,0;MQSB=0.801124;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,131:4:0 0,9,100:3:0 +17 2671 . C 0 . DP=22;I16=17,5,0,0,842,32448,0,0,1258,73682,0,0,386,8110,0,0;QS=3,0;MQSB=0.895399;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,128:4:0 0,6,70:2:0 +17 2672 . C 0 . DP=22;I16=17,5,0,0,808,30180,0,0,1258,73682,0,0,388,8164,0,0;QS=3,0;MQSB=0.895399;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,129:4:0 0,6,75:2:0 +17 2673 . C 0 . DP=22;I16=17,5,0,0,842,32528,0,0,1258,73682,0,0,390,8246,0,0;QS=3,0;MQSB=0.895399;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,133:4:0 0,6,75:2:0 +17 2674 . T 0 . DP=23;I16=17,6,0,0,860,33242,0,0,1318,77282,0,0,392,8356,0,0;QS=3,0;MQSB=0.92854;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,142:4:0 0,6,79:2:0 +17 2675 . T 0 . DP=22;I16=16,6,0,0,756,26986,0,0,1258,73682,0,0,394,8392,0,0;QS=3,0;MQSB=0.934321;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,134:4:0 0,6,74:2:0 +17 2676 . T 0 . DP=22;I16=16,6,0,0,774,28022,0,0,1258,73682,0,0,396,8452,0,0;QS=3,0;MQSB=0.934321;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,135:4:0 0,6,75:2:0 +17 2677 . C 0 . DP=22;I16=16,6,0,0,866,34444,0,0,1258,73682,0,0,398,8536,0,0;QS=3,0;MQSB=0.934321;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,131:4:0 0,6,77:2:0 +17 2678 . T 0 . DP=22;I16=16,5,0,0,818,32216,0,0,1229,72841,0,0,374,7970,0,0;QS=3,0;MQSB=0.978919;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,111:3:0 0,6,80:2:0 +17 2679 . T 0 . DP=22;I16=16,6,0,0,808,29912,0,0,1258,73682,0,0,400,8680,0,0;QS=3,0;MQSB=0.934321;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,137:4:0 0,6,75:2:0 +17 2680 . C 0 . DP=23;I16=16,7,0,0,873,33605,0,0,1318,77282,0,0,400,8740,0,0;QS=3,0;MQSB=0.955805;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,131:4:0 0,6,70:2:0 +17 2681 . T 0 . DP=22;I16=15,7,0,0,820,31248,0,0,1258,73682,0,0,402,8824,0,0;QS=3,0;MQSB=0.961028;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,133:4:0 0,6,75:2:0 +17 2682 . G 0 . DP=22;I16=15,7,0,0,831,31865,0,0,1258,73682,0,0,403,8881,0,0;QS=3,0;MQSB=0.961028;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,135:4:0 0,6,64:2:0 +17 2683 . G 0 . DP=22;I16=13,6,0,0,702,26368,0,0,1109,65641,0,0,394,8926,0,0;QS=3,0;MQSB=0.850016;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,136:4:0 0,6,53:2:0 +17 2684 . G 0 . DP=22;I16=14,7,0,0,754,27678,0,0,1229,72841,0,0,403,9057,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,128:4:0 0,6,62:2:0 +17 2685 . G 0 . DP=22;I16=15,7,0,0,736,25916,0,0,1258,73682,0,0,406,9184,0,0;QS=3,0;MQSB=0.961028;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,130:4:0 0,6,45:2:0 +17 2686 . C 0 . DP=22;I16=15,7,0,0,803,29933,0,0,1258,73682,0,0,406,9278,0,0;QS=3,0;MQSB=0.961028;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,134:4:0 0,6,68:2:0 +17 2687 . A 0 . DP=21;I16=13,7,0,0,716,26356,0,0,1169,69241,0,0,406,9340,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,136:4:0 0,6,61:2:0 +17 2688 . C 0 . DP=20;I16=13,7,0,0,750,28308,0,0,1169,69241,0,0,407,9417,0,0;QS=3,0;MQSB=0.875769;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,134:4:0 0,6,66:2:0 +17 2689 . A 0 . DP=19;I16=12,7,0,0,741,29105,0,0,1109,65641,0,0,409,9507,0,0;QS=3,0;MQSB=0.879351;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,140:4:0 0,6,73:2:0 +17 2690 . G 0 . DP=20;I16=12,8,0,0,751,28929,0,0,1169,69241,0,0,411,9609,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,135:4:0 0,6,61:2:0 +17 2691 . G 0 . DP=20;I16=12,7,0,0,682,25006,0,0,1109,65641,0,0,403,9603,0,0;QS=3,0;MQSB=0.879351;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,132:4:0 0,6,63:2:0 +17 2692 . T 0 . DP=20;I16=12,8,0,0,648,21758,0,0,1169,69241,0,0,417,9853,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,125:4:0 0,6,72:2:0 +17 2693 . C 0 . DP=20;I16=12,8,0,0,779,30645,0,0,1169,69241,0,0,418,9898,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,130:4:0 0,6,70:2:0 +17 2694 . A 0 . DP=21;I16=13,8,0,0,723,25649,0,0,1229,72841,0,0,417,9859,0,0;QS=3,0;MQSB=0.895122;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,126:4:0 0,6,73:2:0 +17 2695 . C 0 . DP=20;I16=12,8,0,0,757,28835,0,0,1169,69241,0,0,418,9834,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,130:4:0 0,6,63:2:0 +17 2696 . A 0 . DP=20;I16=12,8,0,0,733,27357,0,0,1169,69241,0,0,419,9823,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,130:4:0 0,6,69:2:0 +17 2697 . C 0 . DP=20;I16=12,8,0,0,738,27604,0,0,1169,69241,0,0,419,9777,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,128:4:0 0,6,66:2:0 +17 2698 . T 0 . DP=21;I16=12,8,0,0,788,31268,0,0,1169,69241,0,0,419,9747,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,144:4:0 0,6,77:2:0 +17 2699 . C 0 . DP=22;I16=13,9,0,0,864,34148,0,0,1258,73682,0,0,443,10309,0,0;QS=3,0;MQSB=0.686045;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,135:4:0 0,9,98:3:0 +17 2700 . T 0 . DP=22;I16=13,9,0,0,850,33296,0,0,1258,73682,0,0,444,10310,0,0;QS=3,0;MQSB=0.686045;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,141:4:0 0,9,105:3:0 +17 2701 . C 0 . DP=22;I16=13,9,0,0,863,34157,0,0,1258,73682,0,0,444,10278,0,0;QS=3,0;MQSB=0.686045;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,140:4:0 0,9,94:3:0 +17 2702 . T 0 . DP=22;I16=13,9,0,0,837,32525,0,0,1258,73682,0,0,444,10262,0,0;QS=3,0;MQSB=0.686045;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,143:4:0 0,9,83:3:0 +17 2703 . T 0 . DP=21;I16=12,8,0,0,717,25881,0,0,1169,69241,0,0,420,9636,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,130:4:0 0,3,32:1:0 +17 2704 . C 0 . DP=21;I16=12,9,0,0,794,30766,0,0,1198,70082,0,0,445,10225,0,0;QS=3,0;MQSB=0.695144;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,137:4:0 0,6,55:2:0 +17 2705 . C 0 . DP=21;I16=12,9,0,0,809,31649,0,0,1198,70082,0,0,445,10205,0,0;QS=3,0;MQSB=0.695144;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,136:4:0 0,6,56:2:0 +17 2706 . A 0 . DP=22;I16=12,10,0,0,820,31386,0,0,1258,73682,0,0,444,10150,0,0;QS=3,0;MQSB=0.731218;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,141:4:0 0,6,70:2:0 +17 2707 . G 0 . DP=22;I16=12,10,0,0,832,32104,0,0,1258,73682,0,0,444,10110,0,0;QS=3,0;MQSB=0.731218;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,139:4:0 0,6,60:2:0 +17 2708 . G 0 . DP=22;I16=12,10,0,0,777,28329,0,0,1258,73682,0,0,444,10086,0,0;QS=3,0;MQSB=0.731218;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,136:4:0 0,6,57:2:0 +17 2709 . T 0 . DP=22;I16=12,9,0,0,761,28341,0,0,1229,72841,0,0,418,9404,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,137:4:0 0,3,39:1:0 +17 2710 . C 0 . DP=23;I16=12,10,0,0,840,32478,0,0,1289,76441,0,0,417,9365,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,134:4:0 0,3,38:1:0 +17 2711 . T 0 . DP=24;I16=13,11,0,0,893,33721,0,0,1378,80882,0,0,442,9970,0,0;QS=3,0;MQSB=0.75304;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,138:4:0 0,6,72:2:0 +17 2712 . A 0 . DP=24;I16=13,11,0,0,889,33333,0,0,1378,80882,0,0,443,9971,0,0;QS=3,0;MQSB=0.75304;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,141:4:0 0,6,65:2:0 +17 2713 . G T, 0 . DP=25;I16=13,11,0,1,915,35485,14,196,1378,80882,29,841,419,9369,25,625;QS=2.72549,0.27451,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.569783;BQB=1;MQ0F=0 PL:DP:DV 0,57,255,57,255,255:19:0 0,12,131,12,131,131:4:0 8,0,31,11,34,42:2:1 +17 2714 . G 0 . DP=25;I16=13,11,0,0,891,33457,0,0,1378,80882,0,0,444,9990,0,0;QS=3,0;MQSB=0.75304;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,132:4:0 0,6,64:2:0 +17 2715 . A 0 . DP=25;I16=13,12,0,0,888,32012,0,0,1407,81723,0,0,446,10014,0,0;QS=3,0;MQSB=0.569783;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,12,135:4:0 0,6,63:2:0 +17 2716 . T 0 . DP=26;I16=13,13,0,0,937,34241,0,0,1467,85323,0,0,446,10012,0,0;QS=3,0;MQSB=0.606531;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,12,134:4:0 0,9,90:3:0 +17 2717 . G 0 . DP=26;I16=13,12,0,0,939,35995,0,0,1438,84482,0,0,422,9410,0,0;QS=3,0;MQSB=0.778801;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,12,134:4:0 0,6,72:2:0 +17 2718 . C 0 . DP=24;I16=12,11,0,0,864,33118,0,0,1318,77282,0,0,425,9457,0,0;QS=3,0;MQSB=0.7613;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,130:4:0 0,6,65:2:0 +17 2719 . A 0 . DP=24;I16=12,12,0,0,911,35371,0,0,1347,78123,0,0,452,10102,0,0;QS=3,0;MQSB=0.582748;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,139:4:0 0,9,99:3:0 +17 2720 . G 0 . DP=24;I16=12,12,0,0,940,37044,0,0,1347,78123,0,0,453,10095,0,0;QS=3,0;MQSB=0.582748;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,136:4:0 0,9,97:3:0 +17 2721 . C 0 . DP=24;I16=12,11,0,0,881,34499,0,0,1318,77282,0,0,429,9485,0,0;QS=3,0;MQSB=0.7613;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,131:4:0 0,6,76:2:0 +17 2722 . T 0 . DP=24;I16=11,13,0,0,898,34310,0,0,1347,78123,0,0,456,10146,0,0;QS=3,0;MQSB=0.633229;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,156:5:0 0,9,98:3:0 +17 2723 . G 0 . DP=25;I16=12,13,0,0,941,36257,0,0,1407,81723,0,0,459,10203,0,0;QS=3,0;MQSB=0.619223;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,184:6:0 0,9,76:3:0 +17 2724 . A 0 . DP=25;I16=12,13,0,0,917,34211,0,0,1407,81723,0,0,462,10234,0,0;QS=3,0;MQSB=0.619223;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,188:6:0 0,9,84:3:0 +17 2725 . G 0 . DP=25;I16=12,12,0,0,916,35656,0,0,1378,80882,0,0,438,9566,0,0;QS=3,0;MQSB=0.786628;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,185:6:0 0,6,67:2:0 +17 2726 . G 0 . DP=25;I16=11,12,0,0,841,31809,0,0,1287,74523,0,0,437,9545,0,0;QS=3,0;MQSB=0.597127;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,186:6:0 0,6,46:2:0 +17 2727 . G 0 . DP=25;I16=12,13,0,0,889,32233,0,0,1407,81723,0,0,464,10182,0,0;QS=3,0;MQSB=0.619223;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,194:7:0 0,6,56:2:0 +17 2728 . G 0 . DP=25;I16=12,13,0,0,883,32287,0,0,1407,81723,0,0,467,10219,0,0;QS=3,0;MQSB=0.619223;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,189:7:0 0,6,50:2:0 +17 2729 . T 0 . DP=25;I16=12,13,0,0,871,31019,0,0,1407,81723,0,0,469,10233,0,0;QS=3,0;MQSB=0.619223;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,189:7:0 0,6,62:2:0 +17 2730 . G 0 . DP=25;I16=12,13,0,0,907,34299,0,0,1407,81723,0,0,471,10275,0,0;QS=3,0;MQSB=0.619223;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,192:7:0 0,6,49:2:0 +17 2731 . C 0 . DP=25;I16=12,13,0,0,893,33027,0,0,1407,81723,0,0,473,10345,0,0;QS=3,0;MQSB=0.619223;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,192:7:0 0,6,52:2:0 +17 2732 . C 0 . DP=25;I16=12,13,0,0,882,32170,0,0,1407,81723,0,0,473,10343,0,0;QS=3,0;MQSB=0.619223;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,195:7:0 0,6,38:2:0 +17 2733 . C A, 0 . DP=25;I16=12,12,0,1,835,30063,13,169,1378,80882,29,841,448,9744,25,625;QS=2.64865,0.351351,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.619223;BQB=1;MQ0F=0 PL:DP:DV 0,48,255,48,255,255:16:0 0,21,187,21,187,187:7:0 7,0,18,10,21,28:2:1 +17 2734 . C 0 . DP=25;I16=12,12,0,0,890,33726,0,0,1378,80882,0,0,449,9797,0,0;QS=3,0;MQSB=0.786628;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,208:8:0 0,3,39:1:0 +17 2735 . T 0 . DP=26;I16=13,12,0,0,955,36875,0,0,1438,84482,0,0,451,9877,0,0;QS=3,0;MQSB=0.778801;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,228:8:0 0,3,41:1:0 +17 2736 . C 0 . DP=26;I16=13,11,0,0,921,35553,0,0,1409,83641,0,0,428,9308,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,220:8:0 0,3,33:1:0 +17 2737 . T 0 . DP=26;I16=13,13,0,0,967,36581,0,0,1467,85323,0,0,475,10403,0,0;QS=3,0;MQSB=0.606531;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,228:8:0 0,6,64:2:0 +17 2738 . T 0 . DP=26;I16=13,13,0,0,895,31873,0,0,1467,85323,0,0,474,10374,0,0;QS=3,0;MQSB=0.606531;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,201:8:0 0,6,47:2:0 +17 2739 . A 0 . DP=26;I16=13,12,0,0,871,31051,0,0,1407,81723,0,0,448,9698,0,0;QS=3,0;MQSB=0.569783;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,224:8:0 0,9,78:3:0 +17 2740 . C 0 . DP=26;I16=14,11,0,0,952,36456,0,0,1438,84482,0,0,448,9674,0,0;QS=3,0;MQSB=0.745495;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,216:8:0 0,6,71:2:0 +17 2741 . C 0 . DP=26;I16=14,11,0,0,945,36141,0,0,1438,84482,0,0,448,9678,0,0;QS=3,0;MQSB=0.745495;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,215:8:0 0,6,75:2:0 +17 2742 . A 0 . DP=27;I16=15,12,0,0,949,34263,0,0,1527,88923,0,0,472,10284,0,0;QS=3,0;MQSB=0.547344;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,230:9:0 0,9,92:3:0 +17 2743 . T 0 . DP=27;I16=15,12,0,0,955,34479,0,0,1527,88923,0,0,471,10243,0,0;QS=3,0;MQSB=0.547344;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,224:9:0 0,9,99:3:0 +17 2744 . C 0 . DP=26;I16=15,10,0,0,955,36951,0,0,1438,84482,0,0,445,9557,0,0;QS=3,0;MQSB=0.707404;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,234:9:0 0,6,76:2:0 +17 2745 . T 0 . DP=26;I16=15,11,0,0,962,36786,0,0,1467,85323,0,0,469,10151,0,0;QS=3,0;MQSB=0.505697;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,243:9:0 0,9,104:3:0 +17 2746 . A 0 . DP=26;I16=15,10,0,0,912,33536,0,0,1438,84482,0,0,443,9525,0,0;QS=3,0;MQSB=0.707404;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,235:9:0 0,6,78:2:0 +17 2747 . A 0 . DP=26;I16=15,11,0,0,945,35117,0,0,1467,85323,0,0,467,10179,0,0;QS=3,0;MQSB=0.505697;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,238:9:0 0,9,96:3:0 +17 2748 . T 0 . DP=27;I16=15,12,0,0,1005,37901,0,0,1527,88923,0,0,465,10187,0,0;QS=3,0;MQSB=0.547344;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,246:9:0 0,9,103:3:0 +17 2749 . C 0 . DP=26;I16=14,12,0,0,975,37353,0,0,1467,85323,0,0,463,10123,0,0;QS=3,0;MQSB=0.558035;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,232:9:0 0,9,98:3:0 +17 2750 . T 0 . DP=26;I16=15,11,0,0,982,37714,0,0,1498,88082,0,0,462,10086,0,0;QS=3,0;MQSB=0.738577;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,227:8:0 0,12,130:4:0 +17 2751 . G 0 . DP=26;I16=15,10,0,0,945,36031,0,0,1469,87241,0,0,437,9451,0,0;QS=3,0;MQSB=0.9171;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,205:8:0 0,9,103:3:0 +17 2752 . T 0 . DP=26;I16=15,11,0,0,870,30288,0,0,1498,88082,0,0,460,9998,0,0;QS=3,0;MQSB=0.738577;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,189:8:0 0,12,119:4:0 +17 2753 . G 0 . DP=26;I16=15,11,0,0,867,30913,0,0,1498,88082,0,0,458,9948,0,0;QS=3,0;MQSB=0.738577;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,202:8:0 0,12,116:4:0 +17 2754 . C 0 . DP=25;I16=14,10,0,0,873,32607,0,0,1409,83641,0,0,436,9484,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,205:8:0 0,9,104:3:0 +17 2755 . C 0 . DP=25;I16=14,10,0,0,865,32243,0,0,1409,83641,0,0,436,9528,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,209:8:0 0,9,97:3:0 +17 2756 . C 0 . DP=25;I16=14,9,0,0,838,31276,0,0,1380,82800,0,0,411,8971,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,204:8:0 0,9,97:3:0 +17 2757 . T 0 . DP=25;I16=14,11,0,0,904,33980,0,0,1438,84482,0,0,455,10011,0,0;QS=3,0;MQSB=0.745495;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,212:7:0 0,15,147:5:0 +17 2758 . T 0 . DP=25;I16=14,10,0,0,841,30293,0,0,1409,83641,0,0,439,9801,0,0;QS=3,0;MQSB=0.919431;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,195:7:0 0,12,133:4:0 +17 2759 . A 0 . DP=25;I16=14,11,0,0,884,31728,0,0,1438,84482,0,0,457,10195,0,0;QS=3,0;MQSB=0.745495;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,192:7:0 0,15,147:5:0 +17 2760 . T 0 . DP=25;I16=14,11,0,0,907,33965,0,0,1438,84482,0,0,457,10275,0,0;QS=3,0;MQSB=0.745495;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,204:7:0 0,15,150:5:0 +17 2761 . T 0 . DP=23;I16=13,9,0,0,838,32530,0,0,1289,76441,0,0,444,10130,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,185:6:0 0,12,141:4:0 +17 2762 . T 0 . DP=24;I16=13,11,0,0,869,32261,0,0,1378,80882,0,0,459,10395,0,0;QS=3,0;MQSB=0.75304;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,178:6:0 0,18,177:6:0 +17 2763 . C A, 0 . DP=24;I16=13,10,0,1,843,31711,13,169,1349,80041,29,841,448,10290,12,144;QS=2.93333,0.0666667,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.75304;BQB=1;MQ0F=0 PL:DP:DV 0,36,255,36,255,255:12:0 0,18,170,18,170,170:6:0 0,5,147,15,150,153:6:1 +17 2764 . C 0 . DP=24;I16=13,10,0,0,854,32376,0,0,1349,80041,0,0,450,10374,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,163:6:0 0,15,162:5:0 +17 2765 . T 0 . DP=24;I16=12,11,0,0,853,32173,0,0,1318,77282,0,0,457,10469,0,0;QS=3,0;MQSB=0.7613;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,154:5:0 0,18,189:6:0 +17 2766 . C 0 . DP=24;I16=12,11,0,0,887,34485,0,0,1349,80041,0,0,448,10398,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,160:5:0 0,18,186:6:0 +17 2767 . T 0 . DP=24;I16=12,12,0,0,905,34757,0,0,1378,80882,0,0,458,10510,0,0;QS=3,0;MQSB=0.786628;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,153:5:0 0,21,217:7:0 +17 2768 . G 0 . DP=23;I16=11,11,0,0,852,33258,0,0,1289,76441,0,0,452,10462,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,141:5:0 0,18,197:6:0 +17 2769 . C 0 . DP=23;I16=11,12,0,0,832,31390,0,0,1318,77282,0,0,459,10481,0,0;QS=3,0;MQSB=0.795196;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,142:5:0 0,21,202:7:0 +17 2770 . T 0 . DP=23;I16=11,12,0,0,828,30854,0,0,1318,77282,0,0,459,10471,0,0;QS=3,0;MQSB=0.795196;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,152:5:0 0,21,199:7:0 +17 2771 . T 0 . DP=23;I16=11,11,0,0,817,30957,0,0,1258,73682,0,0,454,10456,0,0;QS=3,0;MQSB=0.770381;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,154:5:0 0,18,198:6:0 +17 2772 . T 0 . DP=23;I16=11,12,0,0,856,32206,0,0,1318,77282,0,0,459,10511,0,0;QS=3,0;MQSB=0.795196;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,160:5:0 0,21,210:7:0 +17 2773 . A 0 . DP=23;I16=11,12,0,0,828,30664,0,0,1318,77282,0,0,459,10561,0,0;QS=3,0;MQSB=0.795196;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,140:5:0 0,21,209:7:0 +17 2774 . G 0 . DP=22;I16=11,11,0,0,843,32715,0,0,1258,73682,0,0,458,10530,0,0;QS=3,0;MQSB=0.770381;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,154:5:0 0,21,207:7:0 +17 2775 . T 0 . DP=22;I16=10,11,0,0,748,27720,0,0,1198,70082,0,0,432,9892,0,0;QS=3,0;MQSB=0.780412;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,12,115:4:0 0,21,203:7:0 +17 2776 . G 0 . DP=22;I16=12,10,0,0,803,30251,0,0,1289,76441,0,0,456,10470,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,135:5:0 0,21,210:7:0 +17 2777 . A 0 . DP=22;I16=12,10,0,0,852,33524,0,0,1289,76441,0,0,456,10438,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,148:5:0 0,21,220:7:0 +17 2778 . G 0 . DP=23;I16=12,11,0,0,861,33049,0,0,1349,80041,0,0,456,10422,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,154:5:0 0,21,224:7:0 +17 2779 . G 0 . DP=23;I16=11,11,0,0,834,32014,0,0,1289,76441,0,0,432,9798,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,136:4:0 0,21,219:7:0 +17 2780 . A 0 . DP=23;I16=11,11,0,0,792,29162,0,0,1289,76441,0,0,433,9817,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,33,244:11:0 0,12,133:4:0 0,21,215:7:0 +17 2781 . A 0 . DP=23;I16=11,11,0,0,844,33092,0,0,1289,76441,0,0,441,10141,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,15,151:5:0 0,21,233:7:0 +17 2782 . G 0 . DP=23;I16=12,11,0,0,840,31826,0,0,1349,80041,0,0,458,10438,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,154:5:0 0,21,218:7:0 +17 2783 . A 0 . DP=23;I16=11,11,0,0,860,33888,0,0,1289,76441,0,0,432,9790,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,142:4:0 0,21,230:7:0 +17 2784 . G 0 . DP=23;I16=12,11,0,0,860,33092,0,0,1349,80041,0,0,456,10410,0,0;QS=3,0;MQSB=0.934091;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,143:5:0 0,21,212:7:0 +17 2785 . G 0 . DP=23;I16=11,11,0,0,797,29747,0,0,1289,76441,0,0,429,9749,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,134:4:0 0,21,204:7:0 +17 2786 . C 0 . DP=24;I16=12,12,0,0,831,29497,0,0,1409,83641,0,0,451,10309,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,141:5:0 0,21,199:7:0 +17 2787 . C 0 . DP=24;I16=11,12,0,0,792,28454,0,0,1349,80041,0,0,424,9642,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,36,252:12:0 0,12,127:4:0 0,21,200:7:0 +17 2788 . C 0 . DP=23;I16=11,11,0,0,791,29517,0,0,1289,76441,0,0,421,9523,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,125:4:0 0,21,209:7:0 +17 2789 . C 0 . DP=24;I16=13,11,0,0,880,33470,0,0,1409,83641,0,0,443,10051,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,150:5:0 0,21,226:7:0 +17 2790 . T 0 . DP=23;I16=13,10,0,0,886,34738,0,0,1349,80041,0,0,442,9976,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,165:5:0 0,21,227:7:0 +17 2791 . G 0 . DP=23;I16=13,10,0,0,873,34037,0,0,1349,80041,0,0,441,9923,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,155:5:0 0,21,226:7:0 +17 2792 . G 0 . DP=23;I16=13,10,0,0,832,30870,0,0,1349,80041,0,0,438,9792,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,15,146:5:0 0,21,221:7:0 +17 2793 . T 0 . DP=23;I16=13,10,0,0,827,30693,0,0,1349,80041,0,0,435,9683,0,0;QS=3,0;MQSB=0.921963;MQ0F=0 PL:DP:DV 0,33,247:11:0 0,15,157:5:0 0,21,214:7:0 +17 2794 . C 0 . DP=22;I16=12,10,0,0,786,29122,0,0,1289,76441,0,0,433,9595,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,145:5:0 0,21,201:7:0 +17 2795 . C 0 . DP=22;I16=11,10,0,0,814,31804,0,0,1229,72841,0,0,428,9518,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,27,240:9:0 0,15,159:5:0 0,21,222:7:0 +17 2796 . A 0 . DP=22;I16=11,10,0,0,762,28412,0,0,1229,72841,0,0,427,9475,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,27,221:9:0 0,15,156:5:0 0,21,211:7:0 +17 2797 . T 0 . DP=22;I16=12,10,0,0,792,29116,0,0,1289,76441,0,0,427,9451,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,15,148:5:0 0,21,214:7:0 +17 2798 . G 0 . DP=22;I16=12,10,0,0,817,31105,0,0,1289,76441,0,0,424,9394,0,0;QS=3,0;MQSB=0.924723;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,152:5:0 0,21,205:7:0 +17 2799 . A 0 . DP=21;I16=11,10,0,0,788,30210,0,0,1229,72841,0,0,421,9309,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,27,220:9:0 0,15,167:5:0 0,21,218:7:0 +17 2800 . A 0 . DP=21;I16=11,10,0,0,836,33616,0,0,1229,72841,0,0,418,9246,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,27,237:9:0 0,15,164:5:0 0,21,237:7:0 +17 2801 . G 0 . DP=21;I16=11,10,0,0,792,30182,0,0,1229,72841,0,0,415,9205,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,27,234:9:0 0,15,157:5:0 0,21,214:7:0 +17 2802 . G 0 . DP=21;I16=11,9,0,0,729,27275,0,0,1169,69241,0,0,387,8559,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,24,229:8:0 0,15,135:5:0 0,21,215:7:0 +17 2803 . G 0 . DP=21;I16=11,10,0,0,737,26709,0,0,1229,72841,0,0,406,9036,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,15,125:5:0 0,21,207:7:0 +17 2804 . G 0 . DP=21;I16=11,10,0,0,727,26103,0,0,1229,72841,0,0,400,8908,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,27,218:9:0 0,15,129:5:0 0,21,210:7:0 +17 2805 . C 0 . DP=21;I16=10,10,0,0,714,26194,0,0,1169,69241,0,0,372,8316,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,27,229:9:0 0,12,111:4:0 0,21,205:7:0 +17 2806 . C 0 . DP=20;I16=11,8,0,0,682,25074,0,0,1109,65641,0,0,379,8611,0,0;QS=3,0;MQSB=0.902014;MQ0F=0 PL:DP:DV 0,24,215:8:0 0,15,138:5:0 0,18,191:6:0 +17 2807 . T 0 . DP=20;I16=11,9,0,0,755,29373,0,0,1169,69241,0,0,384,8640,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,15,152:5:0 0,21,227:7:0 +17 2808 . T 0 . DP=20;I16=11,9,0,0,749,28383,0,0,1169,69241,0,0,379,8587,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,24,209:8:0 0,15,157:5:0 0,21,225:7:0 +17 2809 . T 0 . DP=20;I16=11,8,0,0,697,26019,0,0,1109,65641,0,0,349,7927,0,0;QS=3,0;MQSB=0.902014;MQ0F=0 PL:DP:DV 0,21,189:7:0 0,15,148:5:0 0,21,226:7:0 +17 2810 . C 0 . DP=20;I16=12,8,0,0,754,28900,0,0,1169,69241,0,0,368,8436,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,24,229:8:0 0,15,150:5:0 0,21,215:7:0 +17 2811 . A 0 . DP=19;I16=11,8,0,0,759,30405,0,0,1109,65641,0,0,364,8340,0,0;QS=3,0;MQSB=0.902014;MQ0F=0 PL:DP:DV 0,21,209:7:0 0,15,166:5:0 0,21,228:7:0 +17 2812 . G 0 . DP=20;I16=11,9,0,0,758,29062,0,0,1169,69241,0,0,359,8213,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,24,229:8:0 0,15,150:5:0 0,21,216:7:0 +17 2813 . A 0 . DP=19;I16=11,8,0,0,702,27106,0,0,1140,68400,0,0,356,8104,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,195:7:0 0,15,160:5:0 0,21,217:7:0 +17 2814 . G 0 . DP=19;I16=11,8,0,0,703,26579,0,0,1140,68400,0,0,353,8013,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,217:7:0 0,15,147:5:0 0,21,204:7:0 +17 2815 . A 0 . DP=19;I16=10,7,0,0,597,21979,0,0,1020,61200,0,0,326,7470,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,170:6:0 0,12,122:4:0 0,21,208:7:0 +17 2816 . C 0 . DP=19;I16=11,8,0,0,630,21880,0,0,1140,68400,0,0,343,7685,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,193:7:0 0,15,134:5:0 0,21,180:7:0 +17 2817 . G 0 . DP=20;I16=11,8,0,0,612,20368,0,0,1140,68400,0,0,339,7547,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,200:7:0 0,15,115:5:0 0,21,178:7:0 +17 2818 . G 0 . DP=20;I16=11,8,0,0,688,25280,0,0,1140,68400,0,0,335,7377,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,216:7:0 0,15,132:5:0 0,21,206:7:0 +17 2819 . G 0 . DP=20;I16=11,8,0,0,696,25880,0,0,1140,68400,0,0,331,7227,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,222:7:0 0,15,142:5:0 0,21,195:7:0 +17 2820 . G 0 . DP=20;I16=10,8,0,0,624,22228,0,0,1080,64800,0,0,320,7048,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,205:7:0 0,12,119:4:0 0,21,188:7:0 +17 2821 . A 0 . DP=20;I16=9,7,0,0,496,16222,0,0,960,57600,0,0,279,6157,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,159:6:0 0,9,93:3:0 0,21,171:7:0 +17 2822 . C 0 . DP=19;I16=8,9,0,0,543,18163,0,0,1020,61200,0,0,310,7064,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,203:7:0 0,9,79:3:0 0,21,168:7:0 +17 2823 . C 0 . DP=18;I16=9,7,0,0,550,19506,0,0,960,57600,0,0,300,6640,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,201:7:0 0,6,58:2:0 0,21,192:7:0 +17 2824 . C 0 . DP=18;I16=9,7,0,0,584,21560,0,0,960,57600,0,0,299,6567,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,219:8:0 0,3,37:1:0 0,21,210:7:0 +17 2825 . C 0 . DP=18;I16=9,8,0,0,606,22286,0,0,1020,61200,0,0,324,7134,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,234:8:0 0,3,37:1:0 0,24,208:8:0 +17 2826 . T 0 . DP=18;I16=9,8,0,0,604,21766,0,0,1020,61200,0,0,323,7043,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,222:8:0 0,3,33:1:0 0,24,220:8:0 +17 2827 . G 0 . DP=18;I16=9,8,0,0,597,21643,0,0,1020,61200,0,0,322,6970,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,230:8:0 0,3,28:1:0 0,24,214:8:0 +17 2828 . A 0 . DP=20;I16=9,9,0,0,598,20740,0,0,1080,64800,0,0,321,6915,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,213:9:0 0,3,36:1:0 0,24,219:8:0 +17 2829 . G 0 . DP=20;I16=9,9,0,0,649,23719,0,0,1080,64800,0,0,305,6591,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,239:8:0 0,3,31:1:0 0,27,227:9:0 +17 2830 . G 0 . DP=20;I16=9,10,0,0,661,23841,0,0,1140,68400,0,0,323,6867,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,248:9:0 0,3,34:1:0 0,27,222:9:0 +17 2831 . A 0 . DP=21;I16=10,10,0,0,682,24052,0,0,1200,72000,0,0,324,6876,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,223:9:0 0,3,34:1:0 0,30,254:10:0 +17 2832 . G 0 . DP=21;I16=10,8,0,0,626,22384,0,0,1080,64800,0,0,281,5883,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,230:8:0 0,3,31:1:0 0,27,223:9:0 +17 2833 . C 0 . DP=21;I16=10,10,0,0,712,25708,0,0,1200,72000,0,0,327,6915,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,3,37:1:0 0,30,255:10:0 +17 2834 . C 0 . DP=21;I16=10,9,0,0,674,24470,0,0,1140,68400,0,0,306,6464,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,230:8:0 0,3,36:1:0 0,30,243:10:0 +17 2835 . C 0 . DP=20;I16=9,9,0,0,617,21835,0,0,1080,64800,0,0,305,6381,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,202:8:0 0,3,39:1:0 0,27,235:9:0 +17 2836 . C 0 . DP=20;I16=9,9,0,0,580,19624,0,0,1080,64800,0,0,306,6412,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,206:8:0 0,3,39:1:0 0,27,200:9:0 +17 2837 . G 0 . DP=21;I16=9,10,0,0,558,17614,0,0,1140,68400,0,0,330,7086,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,207:9:0 0,3,31:1:0 0,27,193:9:0 +17 2838 . A 0 . DP=20;I16=9,10,0,0,640,22674,0,0,1140,68400,0,0,331,7065,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,245:9:0 0,3,17:1:0 0,27,220:9:0 +17 2839 . G 0 . DP=20;I16=9,8,0,0,623,23267,0,0,1020,61200,0,0,282,5816,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,248:8:0 0,3,26:1:0 0,24,212:8:0 +17 2840 . C 0 . DP=20;I16=9,10,0,0,644,22798,0,0,1140,68400,0,0,333,7089,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,3,32:1:0 0,27,227:9:0 +17 2841 . A 0 . DP=20;I16=9,9,0,0,675,25801,0,0,1080,64800,0,0,309,6509,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,252:9:0 0,3,35:1:0 0,24,234:8:0 +17 2842 . G 0 . DP=20;I16=9,10,0,0,688,25554,0,0,1140,68400,0,0,332,7056,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,3,31:1:0 0,27,233:9:0 +17 2843 . C 0 . DP=20;I16=8,10,0,0,651,23969,0,0,1080,64800,0,0,309,6517,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,0,0:0:0 0,24,211:8:0 +17 2844 . A 0 . DP=20;I16=8,11,0,0,685,25399,0,0,1140,68400,0,0,331,6969,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,0,0:0:0 0,27,231:9:0 +17 2845 . G 0 . DP=20;I16=8,10,0,0,673,25399,0,0,1080,64800,0,0,311,6561,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,0,0:0:0 0,24,228:8:0 +17 2846 . C 0 . DP=20;I16=8,10,0,0,617,22007,0,0,1080,64800,0,0,311,6577,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,0,0:0:0 0,24,218:8:0 +17 2847 . C 0 . DP=20;I16=7,11,0,0,580,19468,0,0,1080,64800,0,0,321,6917,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,241:10:0 0,0,0:0:0 0,24,187:8:0 +17 2848 . G 0 . DP=19;I16=7,10,0,0,542,17884,0,0,1020,61200,0,0,323,6999,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,218:9:0 0,0,0:0:0 0,24,191:8:0 +17 2849 . T 0 . DP=19;I16=7,11,0,0,609,21717,0,0,1080,64800,0,0,341,7357,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,231:9:0 0,0,0:0:0 0,27,214:9:0 +17 2850 . C 0 . DP=19;I16=7,11,0,0,574,18980,0,0,1080,64800,0,0,343,7461,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,234:9:0 0,0,0:0:0 0,27,188:9:0 +17 2851 . G 0 . DP=17;I16=6,11,0,0,589,20831,0,0,1020,61200,0,0,346,7584,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,0,0:0:0 0,24,194:8:0 +17 2852 . T 0 . DP=17;I16=6,11,0,0,625,23241,0,0,1020,61200,0,0,348,7676,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,0,0:0:0 0,24,214:8:0 +17 2853 . G 0 . DP=17;I16=6,11,0,0,635,23949,0,0,1020,61200,0,0,349,7739,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,0,0:0:0 0,24,202:8:0 +17 2854 . T 0 . DP=17;I16=6,11,0,0,602,21990,0,0,1020,61200,0,0,348,7722,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,0,0:0:0 0,24,207:8:0 +17 2855 . C 0 . DP=17;I16=6,10,0,0,577,21539,0,0,960,57600,0,0,337,7623,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,0,0:0:0 0,21,185:7:0 +17 2856 . T 0 . DP=17;I16=6,8,0,0,530,20570,0,0,840,50400,0,0,289,6507,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,252:9:0 0,0,0:0:0 0,15,167:5:0 +17 2857 . C 0 . DP=18;I16=6,10,0,0,577,21641,0,0,960,57600,0,0,336,7664,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,0,0:0:0 0,21,185:7:0 +17 2858 . A 0 . DP=19;I16=6,12,0,0,634,23006,0,0,1080,64800,0,0,355,8081,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,254:10:0 0,3,39:1:0 0,21,185:7:0 +17 2859 . C 0 . DP=19;I16=6,13,0,0,646,23056,0,0,1140,68400,0,0,361,8139,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,3,26:1:0 0,24,194:8:0 +17 2860 . C 0 . DP=19;I16=6,13,0,0,655,23687,0,0,1140,68400,0,0,360,8166,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,251:10:0 0,3,37:1:0 0,24,200:8:0 +17 2861 . C 0 . DP=20;I16=7,12,0,0,708,26756,0,0,1140,68400,0,0,333,7537,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,38:1:0 0,21,203:7:0 +17 2862 . A 0 . DP=20;I16=6,13,0,0,749,29753,0,0,1140,68400,0,0,332,7554,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,3,43:1:0 0,24,225:8:0 +17 2863 . G 0 . DP=19;I16=7,12,0,0,707,26901,0,0,1140,68400,0,0,356,8166,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,35:1:0 0,21,195:7:0 +17 2864 . G 0 . DP=19;I16=7,11,0,0,677,25833,0,0,1080,64800,0,0,352,8070,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,36:1:0 0,18,185:6:0 +17 2865 . G 0 . DP=19;I16=7,12,0,0,671,24569,0,0,1140,68400,0,0,350,7994,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,27:1:0 0,21,193:7:0 +17 2866 . T 0 . DP=18;I16=6,11,0,0,591,21071,0,0,1020,61200,0,0,338,7834,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,3,32:1:0 0,15,147:5:0 +17 2867 . G 0 . DP=18;I16=7,11,0,0,655,24279,0,0,1080,64800,0,0,347,7889,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,58:2:0 0,15,150:5:0 +17 2868 . T 0 . DP=18;I16=7,11,0,0,640,23702,0,0,1080,64800,0,0,347,7859,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,68:2:0 0,15,157:5:0 +17 2869 . C 0 . DP=18;I16=7,11,0,0,655,24737,0,0,1080,64800,0,0,346,7794,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,56:2:0 0,15,165:5:0 +17 2870 . T 0 . DP=18;I16=7,11,0,0,700,27480,0,0,1080,64800,0,0,345,7743,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,70:2:0 0,15,176:5:0 +17 2871 . G 0 . DP=18;I16=7,11,0,0,700,27554,0,0,1080,64800,0,0,344,7706,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,68:2:0 0,15,172:5:0 +17 2872 . A 0 . DP=18;I16=7,11,0,0,651,23869,0,0,1080,64800,0,0,343,7683,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,66:2:0 0,15,171:5:0 +17 2873 . A 0 . DP=18;I16=7,11,0,0,664,25000,0,0,1080,64800,0,0,342,7674,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,61:2:0 0,15,159:5:0 +17 2874 . A 0 . DP=18;I16=7,11,0,0,636,23286,0,0,1080,64800,0,0,341,7679,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,57:2:0 0,15,162:5:0 +17 2875 . C 0 . DP=18;I16=7,11,0,0,664,25148,0,0,1080,64800,0,0,340,7698,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,63:2:0 0,15,166:5:0 +17 2876 . A 0 . DP=18;I16=6,11,0,0,666,26684,0,0,1020,61200,0,0,314,7106,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,6,74:2:0 0,15,185:5:0 +17 2877 . G 0 . DP=17;I16=6,11,0,0,659,26009,0,0,1020,61200,0,0,339,7777,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,6,67:2:0 0,12,148:4:0 +17 2878 . A 0 . DP=17;I16=7,10,0,0,628,23656,0,0,1020,61200,0,0,340,7834,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,6,69:2:0 0,15,166:5:0 +17 2879 . T 0 . DP=18;I16=7,11,0,0,671,25359,0,0,1080,64800,0,0,342,7902,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,9,96:3:0 0,15,175:5:0 +17 2880 . G 0 . DP=19;I16=8,11,0,0,708,26694,0,0,1140,68400,0,0,345,7983,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,118:4:0 0,15,173:5:0 +17 2881 . T 0 . DP=19;I16=6,11,0,0,618,23304,0,0,1020,61200,0,0,299,6829,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,209:8:0 0,12,124:4:0 0,15,178:5:0 +17 2882 . G 0 . DP=19;I16=8,11,0,0,700,26464,0,0,1140,68400,0,0,353,8191,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,118:4:0 0,15,176:5:0 +17 2883 . G 0 . DP=19;I16=8,11,0,0,707,26939,0,0,1140,68400,0,0,357,8319,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,121:4:0 0,15,175:5:0 +17 2884 . A 0 . DP=19;I16=7,11,0,0,649,24531,0,0,1080,64800,0,0,335,7787,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,229:9:0 0,12,121:4:0 0,15,181:5:0 +17 2885 . G 0 . DP=19;I16=8,11,0,0,737,29253,0,0,1140,68400,0,0,362,8470,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,113:4:0 0,15,182:5:0 +17 2886 . G A, 0 . DP=18;I16=7,9,1,0,571,21281,20,400,960,57600,60,3600,334,7882,6,36;QS=2.76471,0.235294,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,27,236,27,236,236:9:0 11,0,51,17,54,66:3:1 0,15,171,15,171,171:5:0 +17 2887 . T 0 . DP=19;I16=9,9,0,0,581,20407,0,0,1080,64800,0,0,341,7905,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,213:10:0 0,9,94:3:0 0,15,166:5:0 +17 2888 . C 0 . DP=20;I16=10,10,0,0,714,26630,0,0,1200,72000,0,0,368,8532,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,94:4:0 0,15,159:5:0 +17 2889 . T 0 . DP=19;I16=9,10,0,0,712,27106,0,0,1140,68400,0,0,372,8550,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,114:4:0 0,15,175:5:0 +17 2890 . C 0 . DP=19;I16=9,10,0,0,613,20711,0,0,1140,68400,0,0,376,8584,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,12,95:4:0 0,15,139:5:0 +17 2891 . G 0 . DP=20;I16=9,11,0,0,674,23754,0,0,1200,72000,0,0,380,8634,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,242:10:0 0,15,141:5:0 0,15,143:5:0 +17 2892 . G 0 . DP=21;I16=9,12,0,0,731,26677,0,0,1260,75600,0,0,385,8701,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,142:5:0 0,15,164:5:0 +17 2893 . G 0 . DP=21;I16=9,12,0,0,696,24498,0,0,1260,75600,0,0,389,8687,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,251:11:0 0,15,141:5:0 0,15,150:5:0 +17 2894 . T 0 . DP=21;I16=9,12,0,0,716,25490,0,0,1260,75600,0,0,393,8693,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,137:5:0 0,15,155:5:0 +17 2895 . G 0 . DP=22;I16=9,12,0,0,773,29225,0,0,1260,75600,0,0,372,8094,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,149:6:0 0,15,166:5:0 +17 2896 . A 0 . DP=22;I16=8,12,0,0,732,27684,0,0,1200,72000,0,0,361,7885,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,151:5:0 0,15,163:5:0 +17 2897 . G 0 . DP=22;I16=10,12,0,0,783,28783,0,0,1320,79200,0,0,407,8835,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,161:6:0 0,15,168:5:0 +17 2898 . G 0 . DP=22;I16=10,12,0,0,724,25596,0,0,1320,79200,0,0,412,8926,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,18,143:6:0 0,15,169:5:0 +17 2899 . C 0 . DP=22;I16=8,11,0,0,625,21143,0,0,1140,68400,0,0,356,7640,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,15,130:5:0 0,15,147:5:0 +17 2900 . G 0 . DP=24;I16=11,13,0,0,782,26700,0,0,1440,86400,0,0,420,9078,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,164:6:0 0,15,153:5:0 +17 2901 . T 0 . DP=24;I16=11,13,0,0,821,29195,0,0,1440,86400,0,0,426,9192,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,174:6:0 0,15,166:5:0 +17 2902 . G 0 . DP=24;I16=11,13,0,0,898,34176,0,0,1440,86400,0,0,432,9334,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,171:6:0 0,15,164:5:0 +17 2903 . G 0 . DP=24;I16=11,13,0,0,894,33764,0,0,1440,86400,0,0,437,9455,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,183:6:0 0,15,168:5:0 +17 2904 . C 0 . DP=24;I16=11,13,0,0,892,34010,0,0,1440,86400,0,0,440,9506,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,176:6:0 0,15,169:5:0 +17 2905 . T 0 . DP=25;I16=12,13,0,0,926,34994,0,0,1500,90000,0,0,442,9536,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,175:6:0 0,15,174:5:0 +17 2906 . C 0 . DP=25;I16=12,13,0,0,960,37070,0,0,1500,90000,0,0,444,9544,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,178:6:0 0,15,173:5:0 +17 2907 . A 0 . DP=25;I16=11,13,0,0,933,36707,0,0,1440,86400,0,0,429,9275,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,202:6:0 0,15,170:5:0 +17 2908 . G 0 . DP=25;I16=12,13,0,0,943,36315,0,0,1500,90000,0,0,446,9548,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,167:6:0 0,15,164:5:0 +17 2909 . A 0 . DP=25;I16=10,13,0,0,864,32764,0,0,1380,82800,0,0,425,9105,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,182:6:0 0,15,171:5:0 +17 2910 . T 0 . DP=25;I16=11,13,0,0,870,32054,0,0,1440,86400,0,0,447,9575,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,181:6:0 0,15,166:5:0 +17 2911 . A 0 . DP=25;I16=11,14,0,0,871,31227,0,0,1500,90000,0,0,473,10259,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,174:6:0 0,18,188:6:0 +17 2912 . C 0 . DP=24;I16=11,13,0,0,899,34121,0,0,1440,86400,0,0,474,10298,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,173:6:0 0,18,189:6:0 +17 2913 . A 0 . DP=24;I16=10,13,0,0,879,34357,0,0,1380,82800,0,0,449,9691,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,164:5:0 0,18,199:6:0 +17 2914 . G 0 . DP=24;I16=11,13,0,0,899,34575,0,0,1440,86400,0,0,472,10262,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,170:6:0 0,18,187:6:0 +17 2915 . G 0 . DP=24;I16=11,13,0,0,867,32523,0,0,1440,86400,0,0,470,10236,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,177:6:0 0,18,178:6:0 +17 2916 . G 0 . DP=24;I16=11,12,0,0,813,29935,0,0,1380,82800,0,0,443,9613,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,173:6:0 0,15,155:5:0 +17 2917 . A 0 . DP=25;I16=11,13,0,0,864,31926,0,0,1440,86400,0,0,459,10181,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,185:6:0 0,18,178:6:0 +17 2918 . G 0 . DP=25;I16=13,12,0,0,903,33489,0,0,1500,90000,0,0,462,10122,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,165:6:0 0,18,170:6:0 +17 2919 . T 0 . DP=25;I16=12,12,0,0,837,29647,0,0,1440,86400,0,0,443,9765,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,169:6:0 0,18,178:6:0 +17 2920 . G 0 . DP=25;I16=12,12,0,0,850,31266,0,0,1440,86400,0,0,433,9389,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,132:5:0 0,18,180:6:0 +17 2921 . G 0 . DP=25;I16=13,12,0,0,874,31518,0,0,1500,90000,0,0,455,9951,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,159:6:0 0,18,176:6:0 +17 2922 . C 0 . DP=26;I16=13,12,0,0,872,31374,0,0,1500,90000,0,0,438,9718,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,160:6:0 0,18,172:6:0 +17 2923 . C 0 . DP=26;I16=13,12,0,0,873,31687,0,0,1500,90000,0,0,437,9735,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,172:6:0 0,18,175:6:0 +17 2924 . C 0 . DP=25;I16=13,12,0,0,940,36016,0,0,1500,90000,0,0,449,9921,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,173:6:0 0,18,184:6:0 +17 2925 . A 0 . DP=25;I16=13,12,0,0,912,33580,0,0,1500,90000,0,0,448,9964,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,174:6:0 0,18,189:6:0 +17 2926 . C 0 . DP=25;I16=13,12,0,0,902,33224,0,0,1500,90000,0,0,445,9931,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,176:6:0 0,18,174:6:0 +17 2927 . A 0 . DP=25;I16=12,12,0,0,896,33828,0,0,1440,86400,0,0,417,9295,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,162:5:0 0,18,191:6:0 +17 2928 . G 0 . DP=24;I16=13,11,0,0,862,32078,0,0,1440,86400,0,0,440,9930,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,170:6:0 0,18,161:6:0 +17 2929 . C 0 . DP=23;I16=13,9,0,0,794,29716,0,0,1320,79200,0,0,430,9878,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,153:5:0 0,15,149:5:0 +17 2930 . T 0 . DP=23;I16=13,10,0,0,822,30260,0,0,1380,82800,0,0,438,10006,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,168:6:0 0,15,157:5:0 +17 2931 . C 0 . DP=23;I16=13,10,0,0,803,28963,0,0,1380,82800,0,0,436,10020,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,162:6:0 0,15,140:5:0 +17 2932 . G 0 . DP=22;I16=12,10,0,0,728,25158,0,0,1320,79200,0,0,435,10049,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,171:6:0 0,12,117:4:0 +17 2933 . G 0 . DP=22;I16=11,10,0,0,760,28336,0,0,1260,75600,0,0,430,10034,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,175:6:0 0,12,116:4:0 +17 2934 . C 0 . DP=21;I16=12,9,0,0,759,28241,0,0,1260,75600,0,0,432,10052,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,161:6:0 0,9,104:3:0 +17 2935 . C 0 . DP=21;I16=12,9,0,0,766,28494,0,0,1260,75600,0,0,431,10075,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,178:6:0 0,9,94:3:0 +17 2936 . T 0 . DP=21;I16=11,9,0,0,760,29284,0,0,1200,72000,0,0,429,10063,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,188:6:0 0,9,98:3:0 +17 2937 . G 0 . DP=20;I16=11,9,0,0,728,27374,0,0,1200,72000,0,0,428,10066,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,177:6:0 0,9,79:3:0 +17 2938 . T 0 . DP=20;I16=11,9,0,0,719,26217,0,0,1200,72000,0,0,427,10083,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,188:6:0 0,9,101:3:0 +17 2939 . C 0 . DP=19;I16=11,8,0,0,729,28277,0,0,1140,68400,0,0,427,10113,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,163:5:0 0,9,106:3:0 +17 2940 . T 0 . DP=19;I16=11,8,0,0,739,29133,0,0,1140,68400,0,0,427,10155,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,171:5:0 0,9,109:3:0 +17 2941 . T 0 . DP=19;I16=11,8,0,0,702,26358,0,0,1140,68400,0,0,427,10209,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,170:5:0 0,9,99:3:0 +17 2942 . T 0 . DP=19;I16=11,8,0,0,695,25671,0,0,1140,68400,0,0,427,10275,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,169:5:0 0,9,100:3:0 +17 2943 . G 0 . DP=18;I16=11,6,0,0,621,23187,0,0,1020,61200,0,0,401,9627,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,15,170:5:0 0,9,86:3:0 +17 2944 . A 0 . DP=18;I16=10,7,0,0,642,24406,0,0,1020,61200,0,0,399,9563,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,15,168:5:0 0,9,111:3:0 +17 2945 . A 0 . DP=18;I16=11,7,0,0,637,23199,0,0,1080,64800,0,0,422,10132,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,242:10:0 0,15,152:5:0 0,9,107:3:0 +17 2946 . A 0 . DP=18;I16=11,7,0,0,692,26794,0,0,1080,64800,0,0,420,10084,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,174:5:0 0,9,108:3:0 +17 2947 . G 0 . DP=18;I16=11,7,0,0,639,23329,0,0,1080,64800,0,0,418,10044,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,160:5:0 0,9,78:3:0 +17 2948 . G 0 . DP=19;I16=11,8,0,0,702,26272,0,0,1140,68400,0,0,415,9961,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,163:5:0 0,12,116:4:0 +17 2949 . C 0 . DP=19;I16=10,8,0,0,657,24565,0,0,1080,64800,0,0,388,9260,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,125:4:0 0,12,124:4:0 +17 2950 . C 0 . DP=19;I16=11,8,0,0,667,24359,0,0,1140,68400,0,0,411,9817,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,131:5:0 0,12,115:4:0 +17 2951 . A 0 . DP=20;I16=11,8,0,0,682,24956,0,0,1140,68400,0,0,409,9757,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,15,149:5:0 0,12,133:4:0 +17 2952 . C 0 . DP=20;I16=11,9,0,0,647,21709,0,0,1200,72000,0,0,408,9706,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,128:5:0 0,12,112:4:0 +17 2953 . G 0 . DP=21;I16=11,9,0,0,620,19954,0,0,1200,72000,0,0,407,9665,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,237:11:0 0,15,132:5:0 0,12,111:4:0 +17 2954 . T 0 . DP=21;I16=11,10,0,0,742,26662,0,0,1260,75600,0,0,414,9666,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,175:6:0 0,12,135:4:0 +17 2955 . G 0 . DP=22;I16=11,11,0,0,787,28475,0,0,1320,79200,0,0,412,9568,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,170:6:0 0,12,127:4:0 +17 2956 . A 0 . DP=22;I16=11,11,0,0,747,26449,0,0,1320,79200,0,0,410,9438,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,161:6:0 0,12,125:4:0 +17 2957 . C 0 . DP=22;I16=10,10,0,0,693,24757,0,0,1200,72000,0,0,358,8078,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,143:6:0 0,9,104:3:0 +17 2958 . C 0 . DP=21;I16=11,10,0,0,784,29744,0,0,1260,75600,0,0,407,9237,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,172:6:0 0,12,135:4:0 +17 2959 . T 0 . DP=21;I16=11,10,0,0,791,30411,0,0,1260,75600,0,0,406,9164,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,182:6:0 0,12,139:4:0 +17 2960 . G 0 . DP=21;I16=11,10,0,0,778,29502,0,0,1260,75600,0,0,405,9109,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,178:6:0 0,12,126:4:0 +17 2961 . G 0 . DP=20;I16=10,9,0,0,657,23303,0,0,1140,68400,0,0,380,8446,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,231:10:0 0,18,176:6:0 0,9,111:3:0 +17 2962 . C 0 . DP=21;I16=10,10,0,0,731,27459,0,0,1200,72000,0,0,385,8615,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,151:5:0 0,12,132:4:0 +17 2963 . C 0 . DP=21;I16=10,10,0,0,722,26502,0,0,1200,72000,0,0,378,8274,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,169:6:0 0,9,100:3:0 +17 2964 . C 0 . DP=22;I16=11,10,0,0,752,27740,0,0,1260,75600,0,0,379,8275,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,148:5:0 0,15,151:5:0 +17 2965 . A 0 . DP=22;I16=11,11,0,0,804,29606,0,0,1320,79200,0,0,397,8539,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,176:6:0 0,15,155:5:0 +17 2966 . C 0 . DP=22;I16=11,11,0,0,705,23557,0,0,1320,79200,0,0,396,8468,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,18,146:6:0 0,15,142:5:0 +17 2967 . G 0 . DP=24;I16=11,13,0,0,767,25405,0,0,1440,86400,0,0,393,8325,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,162:6:0 0,18,135:6:0 +17 2968 . G 0 . DP=23;I16=11,12,0,0,812,29824,0,0,1380,82800,0,0,393,8213,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,152:5:0 0,18,162:6:0 +17 2969 . C 0 . DP=23;I16=11,12,0,0,866,32982,0,0,1380,82800,0,0,393,8133,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,151:5:0 0,18,181:6:0 +17 2970 . T 0 . DP=24;I16=11,12,0,0,816,29806,0,0,1380,82800,0,0,393,8085,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,154:5:0 0,18,189:6:0 +17 2971 . G 0 . DP=24;I16=12,12,0,0,878,33010,0,0,1440,86400,0,0,392,7970,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,173:6:0 0,18,184:6:0 +17 2972 . G 0 . DP=24;I16=12,12,0,0,839,30363,0,0,1440,86400,0,0,391,7889,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,175:6:0 0,18,161:6:0 +17 2973 . C 0 . DP=24;I16=12,12,0,0,854,31154,0,0,1440,86400,0,0,390,7842,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,177:6:0 0,18,165:6:0 +17 2974 . A 0 . DP=24;I16=12,12,0,0,869,32231,0,0,1440,86400,0,0,388,7778,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,169:6:0 0,18,174:6:0 +17 2975 . G 0 . DP=24;I16=12,12,0,0,857,31835,0,0,1440,86400,0,0,384,7648,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,173:6:0 0,18,167:6:0 +17 2976 . G 0 . DP=25;I16=13,12,0,0,866,31118,0,0,1500,90000,0,0,380,7554,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,180:7:0 0,18,171:6:0 +17 2977 . T 0 . DP=26;I16=13,12,0,0,760,25216,0,0,1469,87241,0,0,373,7437,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,151:6:0 0,18,155:6:0 +17 2978 . G 0 . DP=25;I16=12,12,0,0,862,31574,0,0,1409,83641,0,0,362,7290,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,168:6:0 0,18,167:6:0 +17 2979 . G 0 . DP=24;I16=12,12,0,0,816,28440,0,0,1409,83641,0,0,370,7340,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,164:6:0 0,15,142:5:0 +17 2980 . G 0 . DP=23;I16=12,11,0,0,834,30882,0,0,1349,80041,0,0,369,7293,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,144:5:0 0,15,148:5:0 +17 2981 . A 0 . DP=23;I16=9,11,0,0,622,20306,0,0,1169,69241,0,0,318,6244,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,30,201:10:0 0,15,145:5:0 0,15,150:5:0 +17 2982 . C 0 . DP=23;I16=10,11,0,0,706,24366,0,0,1229,72841,0,0,340,6884,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,93:3:0 0,15,144:5:0 +17 2983 . C 0 . DP=23;I16=12,11,0,0,781,27427,0,0,1349,80041,0,0,363,7197,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,137:5:0 0,15,142:5:0 +17 2984 . C 0 . DP=23;I16=12,11,0,0,861,32655,0,0,1349,80041,0,0,361,7229,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,154:5:0 0,15,157:5:0 +17 2985 . A 0 . DP=23;I16=12,11,0,0,798,28906,0,0,1349,80041,0,0,359,7293,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,161:5:0 0,15,151:5:0 +17 2986 . G 0 . DP=21;I16=11,10,0,0,701,24335,0,0,1229,72841,0,0,358,7388,0,0;QS=3,0;MQSB=0.939898;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,129:5:0 0,12,126:4:0 +17 2987 . C 0 . DP=21;I16=10,10,0,0,720,26782,0,0,1169,69241,0,0,350,7448,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,136:4:0 0,12,132:4:0 +17 2988 . T 0 . DP=20;I16=10,10,0,0,693,25143,0,0,1169,69241,0,0,358,7612,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,132:5:0 0,12,136:4:0 +17 2989 . G 0 . DP=20;I16=10,10,0,0,708,25886,0,0,1169,69241,0,0,358,7736,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,141:5:0 0,12,125:4:0 +17 2990 . C 0 . DP=20;I16=10,10,0,0,697,25083,0,0,1169,69241,0,0,357,7833,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,149:5:0 0,12,129:4:0 +17 2991 . A 0 . DP=20;I16=10,10,0,0,717,26309,0,0,1169,69241,0,0,356,7952,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,151:5:0 0,12,131:4:0 +17 2992 . G 0 . DP=18;I16=10,8,0,0,625,22505,0,0,1049,62041,0,0,356,8042,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,12,130:4:0 0,12,120:4:0 +17 2993 . G 0 . DP=18;I16=10,8,0,0,646,23620,0,0,1049,62041,0,0,354,8050,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,118:4:0 0,12,123:4:0 +17 2994 . G 0 . DP=18;I16=10,8,0,0,620,21828,0,0,1049,62041,0,0,351,8025,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,30,254:10:0 0,12,115:4:0 0,12,116:4:0 +17 2995 . G 0 . DP=18;I16=10,8,0,0,628,22284,0,0,1049,62041,0,0,348,8018,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,12,110:4:0 0,12,135:4:0 +17 2996 . T 0 . DP=17;I16=8,8,0,0,497,16697,0,0,929,54841,0,0,323,7493,0,0;QS=3,0;MQSB=0.915545;MQ0F=0 PL:DP:DV 0,30,215:10:0 0,9,75:3:0 0,9,107:3:0 +17 2997 . C 0 . DP=17;I16=9,8,0,0,603,21925,0,0,989,58441,0,0,341,7901,0,0;QS=3,0;MQSB=0.928603;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,85:3:0 0,12,115:4:0 +17 2998 . C 0 . DP=17;I16=9,8,0,0,576,19964,0,0,989,58441,0,0,337,7841,0,0;QS=3,0;MQSB=0.928603;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,9,84:3:0 0,12,123:4:0 +17 2999 . A 0 . DP=17;I16=9,8,0,0,599,22077,0,0,989,58441,0,0,333,7797,0,0;QS=3,0;MQSB=0.928603;MQ0F=0 PL:DP:DV 0,30,238:10:0 0,9,109:3:0 0,12,136:4:0 +17 3000 . G 0 . DP=15;I16=8,7,0,0,554,20620,0,0,869,51241,0,0,331,7767,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,24,220:8:0 0,9,102:3:0 0,12,135:4:0 +17 3001 . C 0 . DP=15;I16=7,7,0,0,521,19695,0,0,809,47641,0,0,309,7349,0,0;QS=3,0;MQSB=0.885987;MQ0F=0 PL:DP:DV 0,21,213:7:0 0,9,103:3:0 0,12,128:4:0 +17 3002 . A 0 . DP=15;I16=8,7,0,0,542,20082,0,0,869,51241,0,0,326,7692,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,24,224:8:0 0,9,92:3:0 0,12,139:4:0 +17 3003 . G 0 . DP=15;I16=8,7,0,0,540,19814,0,0,869,51241,0,0,322,7594,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,24,230:8:0 0,9,96:3:0 0,12,120:4:0 +17 3004 . C 0 . DP=15;I16=8,7,0,0,525,19113,0,0,869,51241,0,0,318,7504,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,24,211:8:0 0,9,100:3:0 0,12,129:4:0 +17 3005 . A 0 . DP=14;I16=7,7,0,0,491,17343,0,0,809,47641,0,0,315,7421,0,0;QS=3,0;MQSB=0.885987;MQ0F=0 PL:DP:DV 0,21,197:7:0 0,9,95:3:0 0,12,124:4:0 +17 3006 . C 0 . DP=16;I16=7,8,0,0,516,18376,0,0,869,51241,0,0,312,7344,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,24,200:8:0 0,9,95:3:0 0,12,135:4:0 +17 3007 . C 0 . DP=16;I16=7,8,0,0,553,20853,0,0,869,51241,0,0,310,7274,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,24,214:8:0 0,9,103:3:0 0,12,144:4:0 +17 3008 . C 0 . DP=16;I16=7,8,0,0,576,22238,0,0,869,51241,0,0,308,7212,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,24,228:8:0 0,9,105:3:0 0,12,145:4:0 +17 3009 . A 0 . DP=16;I16=7,8,0,0,493,16739,0,0,869,51241,0,0,306,7158,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,24,200:8:0 0,9,83:3:0 0,12,130:4:0 +17 3010 . C 0 . DP=15;I16=7,7,0,0,534,20464,0,0,809,47641,0,0,300,7096,0,0;QS=3,0;MQSB=0.885987;MQ0F=0 PL:DP:DV 0,21,211:7:0 0,9,106:3:0 0,12,135:4:0 +17 3011 . A 0 . DP=16;I16=7,8,0,0,559,21173,0,0,869,51241,0,0,302,7074,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,24,218:8:0 0,9,104:3:0 0,12,145:4:0 +17 3012 . G 0 . DP=16;I16=7,8,0,0,503,17903,0,0,869,51241,0,0,300,7044,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,24,193:8:0 0,9,93:3:0 0,12,141:4:0 +17 3013 . C 0 . DP=16;I16=7,9,0,0,549,19967,0,0,898,52082,0,0,305,7071,0,0;QS=3,0;MQSB=0.994413;MQ0F=0 PL:DP:DV 0,27,207:9:0 0,9,98:3:0 0,12,141:4:0 +17 3014 . A 0 . DP=18;I16=6,9,0,0,542,20362,0,0,838,48482,0,0,289,6959,0,0;QS=3,0;MQSB=0.984496;MQ0F=0 PL:DP:DV 0,24,195:8:0 0,9,109:3:0 0,12,141:4:0 +17 3015 . G 0 . DP=20;I16=7,9,0,0,549,19441,0,0,929,54841,0,0,311,7547,0,0;QS=3,0;MQSB=0.892753;MQ0F=0 PL:DP:DV 0,24,206:8:0 0,12,116:4:0 0,12,131:4:0 +17 3016 . C 0 . DP=20;I16=7,13,0,0,690,24374,0,0,1138,66482,0,0,337,7783,0,0;QS=3,0;MQSB=0.972138;MQ0F=0 PL:DP:DV 0,33,248:11:0 0,15,136:5:0 0,12,132:4:0 +17 3017 . C A, 0 . DP=20;I16=7,12,0,1,650,23264,23,529,1109,65641,29,841,329,7715,11,121;QS=2.93801,0.0619946,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.972138;BQB=1;MQ0F=0 PL:DP:DV 0,10,224,30,227,236:11:1 0,15,133,15,133,133:5:0 0,12,128,12,128,128:4:0 +17 3018 . A 0 . DP=21;I16=6,10,0,0,475,15057,0,0,929,54841,0,0,295,6991,0,0;QS=3,0;MQSB=0.863243;MQ0F=0 PL:DP:DV 0,27,192:9:0 0,12,111:4:0 0,9,81:3:0 +17 3019 . C 0 . DP=20;I16=6,12,0,0,618,21842,0,0,1049,62041,0,0,336,7818,0,0;QS=3,0;MQSB=0.85394;MQ0F=0 PL:DP:DV 0,30,242:10:0 0,15,129:5:0 0,9,104:3:0 +17 3020 . C 0 . DP=20;I16=6,12,0,0,588,21046,0,0,1049,62041,0,0,340,7888,0,0;QS=3,0;MQSB=0.85394;MQ0F=0 PL:DP:DV 0,30,221:10:0 0,15,129:5:0 0,9,114:3:0 +17 3021 . T 0 . DP=21;I16=5,13,0,0,618,22454,0,0,1049,62041,0,0,343,7921,0,0;QS=3,0;MQSB=0.814433;MQ0F=0 PL:DP:DV 0,30,216:10:0 0,15,147:5:0 0,9,109:3:0 +17 3022 . G 0 . DP=20;I16=5,13,0,0,672,25292,0,0,1049,62041,0,0,348,7968,0,0;QS=3,0;MQSB=0.814433;MQ0F=0 PL:DP:DV 0,30,234:10:0 0,15,153:5:0 0,9,109:3:0 +17 3023 . T G, 0 . DP=20;I16=5,12,0,1,554,19110,18,324,989,58441,60,3600,336,7740,17,289;QS=2.94231,0.0576923,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.814433;BQB=1;MQ0F=0 PL:DP:DV 0,12,191,27,194,199:10:1 0,15,125,15,125,125:5:0 0,9,111,9,111,111:3:0 +17 3024 . G 0 . DP=20;I16=5,14,0,0,684,25122,0,0,1109,65641,0,0,382,8680,0,0;QS=3,0;MQSB=0.810584;MQ0F=0 PL:DP:DV 0,30,235:10:0 0,18,152:6:0 0,9,113:3:0 +17 3025 . G 0 . DP=20;I16=5,14,0,0,625,21465,0,0,1109,65641,0,0,386,8722,0,0;QS=3,0;MQSB=0.810584;MQ0F=0 PL:DP:DV 0,30,225:10:0 0,18,133:6:0 0,9,109:3:0 +17 3026 . C 0 . DP=20;I16=5,13,0,0,632,23132,0,0,1018,59282,0,0,367,8217,0,0;QS=3,0;MQSB=0.925212;MQ0F=0 PL:DP:DV 0,33,235:11:0 0,12,105:4:0 0,9,107:3:0 +17 3027 . A 0 . DP=21;I16=6,15,0,0,693,24199,0,0,1198,70082,0,0,413,9199,0,0;QS=3,0;MQSB=0.940481;MQ0F=0 PL:DP:DV 0,33,222:11:0 0,21,175:7:0 0,9,108:3:0 +17 3028 . G 0 . DP=21;I16=6,15,0,0,753,27935,0,0,1198,70082,0,0,417,9239,0,0;QS=3,0;MQSB=0.940481;MQ0F=0 PL:DP:DV 0,33,241:11:0 0,21,192:7:0 0,9,107:3:0 +17 3029 . G 0 . DP=21;I16=6,15,0,0,787,29949,0,0,1198,70082,0,0,421,9303,0,0;QS=3,0;MQSB=0.940481;MQ0F=0 PL:DP:DV 0,33,251:11:0 0,21,189:7:0 0,9,109:3:0 +17 3030 . G 0 . DP=22;I16=6,16,0,0,720,24728,0,0,1258,73682,0,0,424,9342,0,0;QS=3,0;MQSB=0.934321;MQ0F=0 PL:DP:DV 0,36,229:12:0 0,21,174:7:0 0,9,106:3:0 +17 3031 . A 0 . DP=22;I16=5,16,0,0,693,24631,0,0,1198,70082,0,0,403,8783,0,0;QS=3,0;MQSB=0.902014;MQ0F=0 PL:DP:DV 0,36,222:12:0 0,18,162:6:0 0,9,113:3:0 +17 3032 . G 0 . DP=22;I16=6,15,0,0,727,26093,0,0,1229,72841,0,0,405,8775,0,0;QS=3,0;MQSB=0.843281;MQ0F=0 PL:DP:DV 0,33,237:11:0 0,21,180:7:0 0,9,106:3:0 +17 3033 . G 0 . DP=22;I16=6,15,0,0,697,24039,0,0,1198,70082,0,0,429,9407,0,0;QS=3,0;MQSB=0.940481;MQ0F=0 PL:DP:DV 0,33,235:11:0 0,21,160:7:0 0,9,106:3:0 +17 3034 . A 0 . DP=23;I16=6,14,0,0,617,20947,0,0,1138,66482,0,0,387,8491,0,0;QS=3,0;MQSB=0.947033;MQ0F=0 PL:DP:DV 0,33,203:11:0 0,15,134:5:0 0,12,126:4:0 +17 3035 . G 0 . DP=23;I16=7,13,0,0,641,22007,0,0,1138,66482,0,0,385,8379,0,0;QS=3,0;MQSB=0.972138;MQ0F=0 PL:DP:DV 0,30,208:10:0 0,18,151:6:0 0,12,128:4:0 +17 3036 . C 0 . DP=23;I16=6,15,0,0,688,23652,0,0,1198,70082,0,0,388,8258,0,0;QS=3,0;MQSB=0.940481;MQ0F=0 PL:DP:DV 0,36,216:12:0 0,15,132:5:0 0,12,140:4:0 +17 3037 . T 0 . DP=24;I16=7,16,0,0,797,28671,0,0,1318,77282,0,0,439,9521,0,0;QS=3,0;MQSB=0.955805;MQ0F=0 PL:DP:DV 0,36,242:12:0 0,21,170:7:0 0,12,143:4:0 +17 3038 . T 0 . DP=25;I16=8,17,0,0,815,27469,0,0,1438,84482,0,0,441,9561,0,0;QS=3,0;MQSB=0.966223;MQ0F=0 PL:DP:DV 0,42,249:14:0 0,21,190:7:0 0,12,125:4:0 +17 3039 . G 0 . DP=25;I16=8,17,0,0,780,25946,0,0,1438,84482,0,0,444,9630,0,0;QS=3,0;MQSB=0.966223;MQ0F=0 PL:DP:DV 0,42,249:14:0 0,21,156:7:0 0,12,127:4:0 +17 3040 . T 0 . DP=25;I16=7,15,0,0,701,23777,0,0,1258,73682,0,0,385,8279,0,0;QS=3,0;MQSB=0.961028;MQ0F=0 PL:DP:DV 0,36,239:12:0 0,18,154:6:0 0,12,130:4:0 +17 3041 . G 0 . DP=25;I16=8,16,0,0,824,29228,0,0,1378,80882,0,0,420,8982,0,0;QS=3,0;MQSB=0.970446;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,186:7:0 0,12,135:4:0 +17 3042 . G 0 . DP=25;I16=8,15,0,0,795,28227,0,0,1349,80041,0,0,409,8839,0,0;QS=3,0;MQSB=0.889418;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,148:6:0 0,12,120:4:0 +17 3043 . T 0 . DP=25;I16=8,16,0,0,723,23191,0,0,1378,80882,0,0,435,9415,0,0;QS=3,0;MQSB=0.970446;MQ0F=0 PL:DP:DV 0,39,233:13:0 0,21,151:7:0 0,12,124:4:0 +17 3044 . A C, 0 . DP=26;I16=8,15,0,1,665,20809,15,225,1318,77282,60,3600,392,8498,14,196;QS=2.96104,0.038961,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.970446;BQB=1;MQ0F=0 PL:DP:DV 0,26,216,39,219,220:14:1 0,18,133,18,133,133:6:0 0,12,124,12,124,124:4:0 +17 3045 . C 0 . DP=26;I16=8,16,0,0,754,25232,0,0,1378,80882,0,0,403,8627,0,0;QS=3,0;MQSB=0.970446;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,133:6:0 0,12,122:4:0 +17 3046 . A 0 . DP=25;I16=8,15,0,0,748,26170,0,0,1349,80041,0,0,400,8540,0,0;QS=3,0;MQSB=0.889418;MQ0F=0 PL:DP:DV 0,39,245:13:0 0,18,160:6:0 0,12,141:4:0 +17 3047 . G 0 . DP=25;I16=8,15,0,0,766,26998,0,0,1318,77282,0,0,396,8432,0,0;QS=3,0;MQSB=0.974802;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,143:6:0 0,12,129:4:0 +17 3048 . T 0 . DP=25;I16=8,11,0,0,608,20554,0,0,1109,65641,0,0,320,6762,0,0;QS=3,0;MQSB=0.902014;MQ0F=0 PL:DP:DV 0,30,226:10:0 0,15,128:5:0 0,12,129:4:0 +17 3049 . G 0 . DP=24;I16=8,16,0,0,831,29557,0,0,1378,80882,0,0,426,9068,0,0;QS=3,0;MQSB=0.970446;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,161:6:0 0,9,105:3:0 +17 3050 . G 0 . DP=24;I16=8,14,0,0,729,25093,0,0,1258,73682,0,0,379,8041,0,0;QS=3,0;MQSB=0.979255;MQ0F=0 PL:DP:DV 0,39,253:13:0 0,18,159:6:0 0,9,100:3:0 +17 3051 . A 0 . DP=23;I16=8,15,0,0,724,24200,0,0,1318,77282,0,0,423,9091,0,0;QS=3,0;MQSB=0.974802;MQ0F=0 PL:DP:DV 0,42,243:14:0 0,18,152:6:0 0,9,103:3:0 +17 3052 . C 0 . DP=23;I16=7,13,0,0,612,19876,0,0,1169,69241,0,0,363,7779,0,0;QS=3,0;MQSB=0.962269;MQ0F=0 PL:DP:DV 0,36,226:12:0 0,15,117:5:0 0,9,93:3:0 +17 3053 . A 0 . DP=22;I16=8,11,0,0,616,21288,0,0,1078,62882,0,0,360,7740,0,0;QS=3,0;MQSB=0.992359;MQ0F=0 PL:DP:DV 0,33,234:11:0 0,15,118:5:0 0,9,110:3:0 +17 3054 . G 0 . DP=22;I16=8,14,0,0,761,27617,0,0,1258,73682,0,0,414,8932,0,0;QS=3,0;MQSB=0.979255;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,126:5:0 0,9,99:3:0 +17 3055 . G 0 . DP=22;I16=8,9,0,0,566,19890,0,0,958,55682,0,0,333,7219,0,0;QS=3,0;MQSB=0.998843;MQ0F=0 PL:DP:DV 0,30,228:10:0 0,12,111:4:0 0,9,105:3:0 +17 3056 . C 0 . DP=22;I16=7,14,0,0,701,24685,0,0,1198,70082,0,0,420,9298,0,0;QS=3,0;MQSB=0.966484;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,125:4:0 0,12,122:4:0 +17 3057 . C 0 . DP=23;I16=8,13,0,0,706,24988,0,0,1198,70082,0,0,411,9253,0,0;QS=3,0;MQSB=0.983744;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,128:5:0 0,9,92:3:0 +17 3058 . C 0 . DP=23;I16=9,14,0,0,707,23327,0,0,1318,77282,0,0,429,9471,0,0;QS=3,0;MQSB=0.987676;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,131:5:0 0,12,116:4:0 +17 3059 . T G, 0 . DP=23;I16=9,11,0,1,638,21954,16,256,1169,69241,60,3600,355,7761,22,484;QS=2.95876,0.0412371,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.913101;BQB=1;MQ0F=0 PL:DP:DV 0,22,234,36,237,239:13:1 0,15,144,15,144,144:5:0 0,9,94,9,94,94:3:0 +17 3060 . G 0 . DP=24;I16=9,10,0,0,578,19136,0,0,1109,65641,0,0,324,6992,0,0;QS=3,0;MQSB=0.920044;MQ0F=0 PL:DP:DV 0,33,221:11:0 0,12,121:4:0 0,12,116:4:0 +17 3061 . C 0 . DP=24;I16=9,15,0,0,770,25918,0,0,1378,80882,0,0,446,10136,0,0;QS=3,0;MQSB=0.984127;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,138:5:0 0,15,145:5:0 +17 3062 . C 0 . DP=23;I16=9,13,0,0,727,25019,0,0,1289,76441,0,0,419,9551,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,137:5:0 0,15,134:5:0 +17 3063 . C 0 . DP=23;I16=9,13,0,0,651,21695,0,0,1258,73682,0,0,415,9511,0,0;QS=3,0;MQSB=0.991121;MQ0F=0 PL:DP:DV 0,36,233:12:0 0,15,130:5:0 0,15,133:5:0 +17 3064 . A 0 . DP=23;I16=9,12,0,0,691,24125,0,0,1198,70082,0,0,385,8815,0,0;QS=3,0;MQSB=0.994334;MQ0F=0 PL:DP:DV 0,36,254:12:0 0,12,118:4:0 0,15,144:5:0 +17 3065 . G 0 . DP=22;I16=7,14,0,0,653,21733,0,0,1198,70082,0,0,426,9986,0,0;QS=3,0;MQSB=0.966484;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,109:4:0 0,12,118:4:0 +17 3066 . A 0 . DP=21;I16=7,10,0,0,501,16143,0,0,989,58441,0,0,326,7598,0,0;QS=3,0;MQSB=0.887766;MQ0F=0 PL:DP:DV 0,27,202:9:0 0,12,109:4:0 0,12,104:4:0 +17 3067 . T 0 . DP=21;I16=7,12,0,0,535,16779,0,0,1078,62882,0,0,373,8787,0,0;QS=3,0;MQSB=0.977926;MQ0F=0 PL:DP:DV 0,36,223:12:0 0,9,82:3:0 0,12,103:4:0 +17 3068 . G 0 . DP=20;I16=7,12,0,0,645,22781,0,0,1109,65641,0,0,396,9312,0,0;QS=3,0;MQSB=0.879351;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,115:4:0 0,9,84:3:0 +17 3069 . G 0 . DP=20;I16=7,10,0,0,468,14412,0,0,989,58441,0,0,346,8070,0,0;QS=3,0;MQSB=0.887766;MQ0F=0 PL:DP:DV 0,33,203:11:0 0,12,102:4:0 0,6,57:2:0 +17 3070 . C 0 . DP=20;I16=6,13,0,0,627,22135,0,0,1078,62882,0,0,414,9878,0,0;QS=3,0;MQSB=0.953977;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,98:3:0 0,9,98:3:0 +17 3071 . C 0 . DP=20;I16=7,13,0,0,715,26563,0,0,1138,66482,0,0,419,9893,0,0;QS=3,0;MQSB=0.972138;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,123:4:0 0,9,98:3:0 +17 3072 . C 0 . DP=20;I16=6,13,0,0,696,25784,0,0,1109,65641,0,0,414,9866,0,0;QS=3,0;MQSB=0.965977;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,128:4:0 0,9,106:3:0 +17 3073 . C 0 . DP=20;I16=6,13,0,0,706,26822,0,0,1109,65641,0,0,414,9872,0,0;QS=3,0;MQSB=0.965977;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,135:4:0 0,9,115:3:0 +17 3074 . C 0 . DP=20;I16=6,13,0,0,724,28052,0,0,1109,65641,0,0,414,9886,0,0;QS=3,0;MQSB=0.965977;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,135:4:0 0,9,116:3:0 +17 3075 . C 0 . DP=21;I16=6,13,0,0,630,21614,0,0,1109,65641,0,0,389,9283,0,0;QS=3,0;MQSB=0.965977;MQ0F=0 PL:DP:DV 0,33,239:11:0 0,15,140:5:0 0,9,94:3:0 +17 3076 . G 0 . DP=21;I16=6,14,0,0,645,21809,0,0,1169,69241,0,0,415,9939,0,0;QS=3,0;MQSB=0.969852;MQ0F=0 PL:DP:DV 0,36,252:12:0 0,15,126:5:0 0,9,91:3:0 +17 3077 . C 0 . DP=20;I16=5,15,0,0,694,25228,0,0,1169,69241,0,0,417,9979,0,0;QS=3,0;MQSB=0.976472;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,116:4:0 0,9,111:3:0 +17 3078 . C 0 . DP=20;I16=5,15,0,0,767,29761,0,0,1169,69241,0,0,420,10028,0,0;QS=3,0;MQSB=0.976472;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,113:4:0 0,9,111:3:0 +17 3079 . T 0 . DP=20;I16=5,15,0,0,749,28479,0,0,1169,69241,0,0,422,10038,0,0;QS=3,0;MQSB=0.976472;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,119:4:0 0,9,116:3:0 +17 3080 . G 0 . DP=21;I16=6,15,0,0,785,29901,0,0,1229,72841,0,0,424,10060,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,124:4:0 0,9,103:3:0 +17 3081 . C 0 . DP=21;I16=6,15,0,0,752,27438,0,0,1229,72841,0,0,425,9997,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,118:4:0 0,9,92:3:0 +17 3082 . C 0 . DP=21;I16=6,15,0,0,787,30211,0,0,1229,72841,0,0,426,9952,0,0;QS=3,0;MQSB=0.973096;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,118:4:0 0,9,112:3:0 +17 3083 . T C, 0 . DP=21;I16=6,14,0,1,764,29458,33,1089,1169,69241,60,3600,401,9249,25,625;QS=2.93666,0.0633397,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.973096;BQB=1;MQ0F=0 PL:DP:DV 0,9,255,39,255,255:14:1 0,12,130,12,130,130:4:0 0,9,113,9,113,113:3:0 +17 3084 . G 0 . DP=23;I16=6,17,0,0,859,32755,0,0,1349,80041,0,0,426,9812,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,118:4:0 0,12,135:4:0 +17 3085 . T 0 . DP=23;I16=6,16,0,0,824,31132,0,0,1289,76441,0,0,426,9718,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,124:4:0 0,12,135:4:0 +17 3086 . G 0 . DP=23;I16=6,17,0,0,853,32429,0,0,1349,80041,0,0,428,9648,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,125:4:0 0,12,131:4:0 +17 3087 . G 0 . DP=23;I16=6,17,0,0,897,35253,0,0,1349,80041,0,0,429,9599,0,0;QS=3,0;MQSB=0.978183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,130:4:0 0,12,137:4:0 +17 3088 . A 0 . DP=22;I16=6,16,0,0,834,31738,0,0,1289,76441,0,0,431,9571,0,0;QS=3,0;MQSB=0.97584;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,110:3:0 0,12,135:4:0 +17 3089 . A 0 . DP=23;I16=7,16,0,0,919,36903,0,0,1349,80041,0,0,432,9514,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,113:3:0 0,15,175:5:0 +17 3090 . G 0 . DP=23;I16=7,16,0,0,885,34349,0,0,1349,80041,0,0,433,9431,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,103:3:0 0,15,160:5:0 +17 3091 . T 0 . DP=23;I16=7,16,0,0,840,31352,0,0,1349,80041,0,0,434,9374,0,0;QS=3,0;MQSB=0.973027;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,105:3:0 0,15,153:5:0 +17 3092 . T 0 . DP=24;I16=8,16,0,0,895,33673,0,0,1409,83641,0,0,434,9294,0,0;QS=3,0;MQSB=0.970446;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,109:3:0 0,15,165:5:0 +17 3093 . G 0 . DP=25;I16=9,16,0,0,955,37033,0,0,1469,87241,0,0,434,9192,0,0;QS=3,0;MQSB=0.968069;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,133:4:0 0,15,157:5:0 +17 3094 . A 0 . DP=25;I16=9,15,0,0,891,33319,0,0,1409,83641,0,0,425,9019,0,0;QS=3,0;MQSB=0.96464;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,134:4:0 0,15,161:5:0 +17 3095 . C 0 . DP=25;I16=9,15,0,0,891,33469,0,0,1409,83641,0,0,425,8955,0,0;QS=3,0;MQSB=0.96464;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,131:4:0 0,15,163:5:0 +17 3096 . C 0 . DP=25;I16=9,16,0,0,952,36626,0,0,1469,87241,0,0,436,9014,0,0;QS=3,0;MQSB=0.968069;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,121:4:0 0,15,167:5:0 +17 3097 . A 0 . DP=25;I16=9,16,0,0,972,38200,0,0,1469,87241,0,0,436,8984,0,0;QS=3,0;MQSB=0.968069;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,144:4:0 0,15,174:5:0 +17 3098 . G 0 . DP=25;I16=9,16,0,0,959,37269,0,0,1469,87241,0,0,436,8986,0,0;QS=3,0;MQSB=0.968069;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,134:4:0 0,15,166:5:0 +17 3099 . A 0 . DP=25;I16=9,16,0,0,888,32632,0,0,1469,87241,0,0,435,8971,0,0;QS=3,0;MQSB=0.968069;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,124:4:0 0,15,165:5:0 +17 3100 . C 0 . DP=25;I16=9,16,0,0,870,31084,0,0,1469,87241,0,0,434,8990,0,0;QS=3,0;MQSB=0.968069;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,126:4:0 0,15,159:5:0 +17 3101 . C 0 . DP=25;I16=9,16,0,0,960,37090,0,0,1469,87241,0,0,432,8992,0,0;QS=3,0;MQSB=0.968069;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,134:4:0 0,15,161:5:0 +17 3102 . A 0 . DP=26;I16=10,16,0,0,952,35186,0,0,1529,90841,0,0,430,9026,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,134:4:0 0,18,189:6:0 +17 3103 . T 0 . DP=26;I16=10,16,0,0,920,33094,0,0,1529,90841,0,0,427,8993,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,131:4:0 0,18,187:6:0 +17 3104 . C T, 0 . DP=25;I16=8,15,2,0,900,35584,80,3202,1349,80041,120,7200,385,8143,40,850;QS=2.58763,0.412371,0;VDB=0.8;SGB=0.346553;RPB=0.717391;MQB=0.956522;MQSB=0.962269;BQB=0.978261;MQ0F=0 PL:DP:DV 0,48,255,48,255,255:16:0 0,12,144,12,144,144:4:0 59,0,93,68,99,157:5:2 +17 3105 . T 0 . DP=25;I16=10,15,0,0,959,37057,0,0,1469,87241,0,0,422,8976,0,0;QS=3,0;MQSB=0.962269;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,12,149:4:0 0,15,169:5:0 +17 3106 . G 0 . DP=23;I16=10,13,0,0,881,33891,0,0,1380,82800,0,0,420,8940,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,132:4:0 0,15,167:5:0 +17 3107 . T 0 . DP=24;I16=10,14,0,0,878,32496,0,0,1440,86400,0,0,418,8932,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,132:4:0 0,18,195:6:0 +17 3108 . C 0 . DP=24;I16=10,14,0,0,909,34897,0,0,1440,86400,0,0,417,8953,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,137:4:0 0,18,189:6:0 +17 3109 . A 0 . DP=24;I16=10,14,0,0,905,34249,0,0,1440,86400,0,0,416,9004,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,136:4:0 0,18,195:6:0 +17 3110 . C 0 . DP=24;I16=10,13,0,0,919,37099,0,0,1380,82800,0,0,413,8933,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,105:3:0 0,18,189:6:0 +17 3111 . A 0 . DP=25;I16=10,14,0,0,961,38943,0,0,1440,86400,0,0,410,8888,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,111:3:0 0,18,205:6:0 +17 3112 . G 0 . DP=25;I16=10,14,0,0,958,39370,0,0,1440,86400,0,0,407,8821,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,116:3:0 0,18,191:6:0 +17 3113 . C 0 . DP=25;I16=10,14,0,0,961,39641,0,0,1440,86400,0,0,403,8735,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,112:3:0 0,18,193:6:0 +17 3114 . A 0 . DP=24;I16=10,13,0,0,928,38448,0,0,1380,82800,0,0,400,8680,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,116:3:0 0,18,200:6:0 +17 3115 . G 0 . DP=23;I16=10,12,0,0,872,35800,0,0,1320,79200,0,0,397,8603,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,117:3:0 0,18,195:6:0 +17 3116 . G 0 . DP=23;I16=10,12,0,0,870,35372,0,0,1320,79200,0,0,394,8552,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,108:3:0 0,18,194:6:0 +17 3117 . T 0 . DP=22;I16=9,13,0,0,771,27537,0,0,1320,79200,0,0,399,8575,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,96:3:0 0,18,177:6:0 +17 3118 . A 0 . DP=22;I16=9,13,0,0,813,30285,0,0,1320,79200,0,0,397,8537,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,111:3:0 0,18,193:6:0 +17 3119 . A 0 . DP=22;I16=9,13,0,0,886,35954,0,0,1320,79200,0,0,393,8423,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,120:3:0 0,18,207:6:0 +17 3120 . G 0 . DP=22;I16=9,13,0,0,839,32281,0,0,1320,79200,0,0,389,8333,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,104:3:0 0,18,182:6:0 +17 3121 . A 0 . DP=22;I16=10,12,0,0,777,28399,0,0,1320,79200,0,0,386,8266,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,111:3:0 0,18,194:6:0 +17 3122 . C 0 . DP=22;I16=10,12,0,0,848,33002,0,0,1320,79200,0,0,384,8222,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,110:3:0 0,18,192:6:0 +17 3123 . T 0 . DP=22;I16=10,12,0,0,854,33456,0,0,1320,79200,0,0,382,8202,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,114:3:0 0,18,204:6:0 +17 3124 . C 0 . DP=22;I16=10,11,0,0,882,38286,0,0,1260,75600,0,0,381,8205,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,104:3:0 0,15,178:5:0 +17 3125 . T 0 . DP=22;I16=10,11,0,0,860,36764,0,0,1260,75600,0,0,380,8230,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,106:3:0 0,15,185:5:0 +17 3126 . G 0 . DP=22;I16=10,11,0,0,834,34998,0,0,1260,75600,0,0,379,8277,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,97:3:0 0,15,174:5:0 +17 3127 . C 0 . DP=23;I16=10,11,0,0,847,36381,0,0,1260,75600,0,0,378,8346,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,87:3:0 0,15,175:5:0 +17 3128 . T 0 . DP=22;I16=9,12,0,0,850,35972,0,0,1229,72841,0,0,402,9010,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,107:3:0 0,15,182:5:0 +17 3129 . T 0 . DP=22;I16=9,12,0,0,809,32621,0,0,1229,72841,0,0,401,9067,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,107:3:0 0,15,178:5:0 +17 3130 . T 0 . DP=21;I16=9,10,0,0,744,30322,0,0,1140,68400,0,0,376,8516,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,82:2:0 0,15,169:5:0 +17 3131 . C 0 . DP=21;I16=9,10,0,0,792,34778,0,0,1140,68400,0,0,376,8606,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,6,83:2:0 0,15,170:5:0 +17 3132 . T 0 . DP=21;I16=9,11,0,0,819,35197,0,0,1169,69241,0,0,400,9288,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,109:3:0 0,15,174:5:0 +17 3133 . G 0 . DP=21;I16=9,11,0,0,800,34016,0,0,1169,69241,0,0,398,9312,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,97:3:0 0,15,166:5:0 +17 3134 . G 0 . DP=22;I16=10,11,0,0,773,30227,0,0,1229,72841,0,0,396,9352,0,0;QS=3,0;MQSB=0.939898;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,97:3:0 0,15,163:5:0 +17 3135 . G 0 . DP=22;I16=9,12,0,0,812,33714,0,0,1229,72841,0,0,396,9408,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,94:3:0 0,12,151:4:0 +17 3136 . C 0 . DP=22;I16=9,12,0,0,811,33469,0,0,1229,72841,0,0,396,9430,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,102:3:0 0,12,140:4:0 +17 3137 . A 0 . DP=22;I16=10,11,0,0,786,31226,0,0,1229,72841,0,0,396,9416,0,0;QS=3,0;MQSB=0.939898;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,95:3:0 0,12,142:4:0 +17 3138 . A 0 . DP=21;I16=9,11,0,0,720,28200,0,0,1169,69241,0,0,398,9414,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,98:3:0 0,12,147:4:0 +17 3139 . C 0 . DP=21;I16=9,11,0,0,755,31433,0,0,1169,69241,0,0,400,9424,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,91:3:0 0,12,139:4:0 +17 3140 . C 0 . DP=21;I16=9,11,0,0,790,33238,0,0,1169,69241,0,0,402,9446,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,102:3:0 0,12,145:4:0 +17 3141 . C 0 . DP=21;I16=9,11,0,0,819,35401,0,0,1169,69241,0,0,404,9480,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,101:3:0 0,12,150:4:0 +17 3142 . A 0 . DP=21;I16=9,11,0,0,822,35744,0,0,1169,69241,0,0,405,9477,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,107:3:0 0,12,155:4:0 +17 3143 . G 0 . DP=22;I16=10,11,0,0,846,36468,0,0,1198,70082,0,0,406,9488,0,0;QS=3,0;MQSB=0.99938;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,104:3:0 0,12,151:4:0 +17 3144 . C 0 . DP=23;I16=12,10,0,0,855,35905,0,0,1258,73682,0,0,409,9513,0,0;QS=3,0;MQSB=0.997828;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,104:3:0 0,15,165:5:0 +17 3145 . A 0 . DP=23;I16=12,10,0,0,869,35937,0,0,1258,73682,0,0,414,9554,0,0;QS=3,0;MQSB=0.997828;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,106:3:0 0,15,174:5:0 +17 3146 . G 0 . DP=23;I16=12,10,0,0,895,38345,0,0,1258,73682,0,0,419,9613,0,0;QS=3,0;MQSB=0.997828;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,105:3:0 0,15,179:5:0 +17 3147 . G 0 . DP=24;I16=11,11,0,0,851,34815,0,0,1289,76441,0,0,419,9623,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,123:4:0 0,15,172:5:0 +17 3148 . T 0 . DP=24;I16=12,11,0,0,795,30097,0,0,1318,77282,0,0,428,9682,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,107:4:0 0,15,149:5:0 +17 3149 . G 0 . DP=24;I16=12,11,0,0,910,38142,0,0,1318,77282,0,0,433,9743,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,120:4:0 0,15,167:5:0 +17 3150 . A 0 . DP=24;I16=12,11,0,0,854,33784,0,0,1318,77282,0,0,438,9822,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,129:4:0 0,15,167:5:0 +17 3151 . C 0 . DP=24;I16=12,11,0,0,873,35315,0,0,1318,77282,0,0,442,9870,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,125:4:0 0,15,163:5:0 +17 3152 . C 0 . DP=24;I16=12,11,0,0,857,34239,0,0,1318,77282,0,0,445,9889,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,123:4:0 0,15,155:5:0 +17 3153 . C 0 . DP=24;I16=12,11,0,0,891,36711,0,0,1318,77282,0,0,448,9930,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,125:4:0 0,15,166:5:0 +17 3154 . T 0 . DP=25;I16=13,11,0,0,938,38052,0,0,1378,80882,0,0,451,9993,0,0;QS=3,0;MQSB=0.998323;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,133:4:0 0,18,194:6:0 +17 3155 . G 0 . DP=25;I16=13,11,0,0,953,39423,0,0,1378,80882,0,0,454,10030,0,0;QS=3,0;MQSB=0.998323;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,127:4:0 0,18,180:6:0 +17 3156 . G 0 . DP=25;I16=13,11,0,0,946,38818,0,0,1378,80882,0,0,457,10093,0,0;QS=3,0;MQSB=0.998323;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,126:4:0 0,18,189:6:0 +17 3157 . A 0 . DP=24;I16=12,12,0,0,896,33648,0,0,1378,80882,0,0,486,10806,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,130:4:0 0,18,193:6:0 +17 3158 . A 0 . DP=24;I16=12,12,0,0,856,31670,0,0,1378,80882,0,0,490,10918,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,125:4:0 0,18,192:6:0 +17 3159 . T 0 . DP=24;I16=11,12,0,0,864,32952,0,0,1349,80041,0,0,477,10749,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,134:4:0 0,18,194:6:0 +17 3160 . T 0 . DP=24;I16=12,12,0,0,907,34719,0,0,1378,80882,0,0,494,11018,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,134:4:0 0,18,193:6:0 +17 3161 . C 0 . DP=24;I16=12,12,0,0,880,33336,0,0,1378,80882,0,0,494,11006,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,123:4:0 0,18,196:6:0 +17 3162 . C 0 . DP=24;I16=12,12,0,0,916,35764,0,0,1378,80882,0,0,494,11018,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,127:4:0 0,18,188:6:0 +17 3163 . T A, 0 . DP=24;I16=11,12,1,0,895,35099,13,169,1349,80041,29,841,473,10603,20,400;QS=2.97436,0.025641,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL:DP:DV 0,28,255,39,255,255:14:1 0,12,137,12,137,137:4:0 0,18,200,18,200,200:6:0 +17 3164 . G 0 . DP=24;I16=12,11,0,0,887,34437,0,0,1349,80041,0,0,467,10385,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,106:3:0 0,18,188:6:0 +17 3165 . T 0 . DP=24;I16=12,12,0,0,880,32654,0,0,1378,80882,0,0,490,10990,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,133:4:0 0,18,189:6:0 +17 3166 . C 0 . DP=24;I16=12,11,0,0,871,33389,0,0,1349,80041,0,0,463,10369,0,0;QS=3,0;MQSB=0.944319;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,111:3:0 0,18,193:6:0 +17 3167 . C 0 . DP=23;I16=12,11,0,0,879,34199,0,0,1318,77282,0,0,487,11021,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,131:4:0 0,18,189:6:0 +17 3168 . A 0 . DP=23;I16=12,11,0,0,874,33294,0,0,1318,77282,0,0,486,11070,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,125:4:0 0,18,192:6:0 +17 3169 . T 0 . DP=23;I16=11,11,0,0,824,31124,0,0,1289,76441,0,0,458,10416,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,128:4:0 0,18,187:6:0 +17 3170 . C 0 . DP=23;I16=11,11,0,0,877,35167,0,0,1289,76441,0,0,453,10307,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,129:4:0 0,18,201:6:0 +17 3171 . T 0 . DP=23;I16=11,11,0,0,843,32615,0,0,1289,76441,0,0,448,10216,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,127:4:0 0,18,201:6:0 +17 3172 . G 0 . DP=23;I16=12,11,0,0,813,29605,0,0,1318,77282,0,0,468,10768,0,0;QS=3,0;MQSB=0.999527;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,120:4:0 0,18,176:6:0 +17 3173 . G 0 . DP=23;I16=11,11,0,0,801,29659,0,0,1289,76441,0,0,436,9988,0,0;QS=3,0;MQSB=0.936864;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,126:4:0 0,18,174:6:0 +17 3174 . C 0 . DP=24;I16=13,11,0,0,938,36926,0,0,1378,80882,0,0,454,10476,0,0;QS=3,0;MQSB=0.998323;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,127:4:0 0,18,194:6:0 +17 3175 . A 0 . DP=25;I16=13,11,0,0,914,35230,0,0,1409,83641,0,0,422,9684,0,0;QS=3,0;MQSB=0.931547;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,127:4:0 0,21,209:7:0 +17 3176 . G 0 . DP=24;I16=14,10,0,0,909,34913,0,0,1378,80882,0,0,442,10164,0,0;QS=3,0;MQSB=0.993166;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,97:3:0 0,21,205:7:0 +17 3177 . G 0 . DP=23;I16=14,9,0,0,793,28159,0,0,1318,77282,0,0,438,10040,0,0;QS=3,0;MQSB=0.987676;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,93:3:0 0,21,195:7:0 +17 3178 . T 0 . DP=23;I16=13,9,0,0,754,26290,0,0,1289,76441,0,0,408,9262,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,96:3:0 0,21,173:7:0 +17 3179 . G 0 . DP=23;I16=13,9,0,0,802,29686,0,0,1289,76441,0,0,403,9131,0,0;QS=3,0;MQSB=0.910098;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,97:3:0 0,21,188:7:0 +17 3180 . G 0 . DP=22;I16=12,9,0,0,701,24107,0,0,1229,72841,0,0,398,8970,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,92:3:0 0,21,175:7:0 +17 3181 . G 0 . DP=22;I16=13,9,0,0,795,29503,0,0,1258,73682,0,0,418,9452,0,0;QS=3,0;MQSB=0.991121;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,99:3:0 0,21,193:7:0 +17 3182 . C 0 . DP=22;I16=12,9,0,0,772,28878,0,0,1198,70082,0,0,396,9038,0,0;QS=3,0;MQSB=0.994334;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,99:3:0 0,21,184:7:0 +17 3183 . A 0 . DP=22;I16=12,9,0,0,766,28304,0,0,1229,72841,0,0,382,8546,0,0;QS=3,0;MQSB=0.913101;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,106:3:0 0,21,193:7:0 +17 3184 . T 0 . DP=21;I16=12,8,0,0,721,26533,0,0,1169,69241,0,0,377,8409,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,9,106:3:0 0,21,196:7:0 +17 3185 . T 0 . DP=20;I16=13,7,0,0,740,27660,0,0,1138,66482,0,0,397,8865,0,0;QS=3,0;MQSB=0.972138;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,103:3:0 0,18,174:6:0 +17 3186 . G 0 . DP=20;I16=13,7,0,0,741,28311,0,0,1138,66482,0,0,391,8665,0,0;QS=3,0;MQSB=0.972138;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,103:3:0 0,18,169:6:0 +17 3187 . A 0 . DP=20;I16=13,7,0,0,693,24927,0,0,1138,66482,0,0,385,8485,0,0;QS=3,0;MQSB=0.972138;MQ0F=0 PL:DP:DV 0,33,247:11:0 0,9,102:3:0 0,18,171:6:0 +17 3188 . A 0 . DP=20;I16=13,7,0,0,704,25746,0,0,1138,66482,0,0,379,8325,0,0;QS=3,0;MQSB=0.972138;MQ0F=0 PL:DP:DV 0,33,249:11:0 0,9,100:3:0 0,18,174:6:0 +17 3189 . A 0 . DP=21;I16=13,8,0,0,763,28171,0,0,1198,70082,0,0,373,8185,0,0;QS=3,0;MQSB=0.983744;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,125:4:0 0,18,174:6:0 +17 3190 . C 0 . DP=20;I16=11,8,0,0,675,24915,0,0,1109,65641,0,0,344,7440,0,0;QS=3,0;MQSB=0.902014;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,123:4:0 0,15,148:5:0 +17 3191 . T 0 . DP=21;I16=11,9,0,0,773,30203,0,0,1169,69241,0,0,340,7340,0,0;QS=3,0;MQSB=0.916401;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,130:4:0 0,15,171:5:0 +17 3192 . G 0 . DP=21;I16=12,9,0,0,751,27785,0,0,1198,70082,0,0,362,7886,0,0;QS=3,0;MQSB=0.994334;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,125:4:0 0,15,152:5:0 +17 3193 . G 0 . DP=21;I16=12,9,0,0,756,27614,0,0,1198,70082,0,0,359,7829,0,0;QS=3,0;MQSB=0.994334;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,121:4:0 0,15,148:5:0 +17 3194 . T C, 0 . DP=21;I16=10,10,1,0,730,26992,18,324,1169,69241,29,841,332,7168,25,625;QS=2.95652,0.0434783,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.99938;BQB=1;MQ0F=0 PL:DP:DV 0,18,255,33,255,255:12:1 0,9,98,9,98,98:3:0 0,18,178,18,178,178:6:0 +17 3195 . T 0 . DP=21;I16=11,10,0,0,776,29184,0,0,1198,70082,0,0,356,7778,0,0;QS=3,0;MQSB=0.99938;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,95:3:0 0,18,189:6:0 +17 3196 . T 0 . DP=21;I16=10,10,0,0,722,26472,0,0,1169,69241,0,0,329,7111,0,0;QS=3,0;MQSB=0.931063;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,91:3:0 0,18,186:6:0 +17 3197 . A 0 . DP=22;I16=12,9,0,0,715,24911,0,0,1229,72841,0,0,352,7718,0,0;QS=3,0;MQSB=0.950149;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,103:3:0 0,18,179:6:0 +17 3198 . A 0 . DP=21;I16=12,8,0,0,745,28155,0,0,1169,69241,0,0,345,7675,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,105:3:0 0,18,198:6:0 +17 3199 . A 0 . DP=21;I16=11,9,0,0,736,27514,0,0,1200,72000,0,0,326,7080,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,105:3:0 0,18,196:6:0 +17 3200 . A 0 . DP=20;I16=11,9,0,0,735,27533,0,0,1169,69241,0,0,350,7660,0,0;QS=3,0;MQSB=0.943233;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,108:3:0 0,18,195:6:0 +17 3201 . A 0 . DP=20;I16=11,8,0,0,706,26814,0,0,1109,65641,0,0,338,7486,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,9,107:3:0 0,18,198:6:0 +17 3202 . T 0 . DP=20;I16=10,9,0,0,692,25620,0,0,1140,68400,0,0,321,6907,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,9,109:3:0 0,18,187:6:0 +17 3203 . G A, 0 . DP=19;I16=9,9,1,0,644,23760,19,361,1080,64800,29,841,320,6872,25,625;QS=2.94823,0.0517711,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.934728;BQB=1;MQ0F=0 PL:DP:DV 0,14,239,30,242,248:11:1 0,9,105,9,105,105:3:0 0,15,160,15,160,160:5:0 +17 3204 . T 0 . DP=19;I16=9,8,0,0,619,22955,0,0,1020,61200,0,0,306,6686,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,234:9:0 0,9,101:3:0 0,15,169:5:0 +17 3205 . C 0 . DP=19;I16=9,9,0,0,672,25340,0,0,1080,64800,0,0,318,6856,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,99:3:0 0,15,157:5:0 +17 3206 . A 0 . DP=19;I16=10,9,0,0,661,23623,0,0,1109,65641,0,0,342,7500,0,0;QS=3,0;MQSB=0.934728;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,91:3:0 0,15,165:5:0 +17 3207 . C 0 . DP=19;I16=9,9,0,0,642,23618,0,0,1080,64800,0,0,316,6912,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,90:3:0 0,15,158:5:0 +17 3208 . A 0 . DP=18;I16=10,8,0,0,619,22023,0,0,1049,62041,0,0,341,7591,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,33,247:11:0 0,9,95:3:0 0,12,142:4:0 +17 3209 . C 0 . DP=19;I16=11,8,0,0,681,24747,0,0,1109,65641,0,0,340,7612,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,106:3:0 0,12,134:4:0 +17 3210 . C 0 . DP=18;I16=11,7,0,0,664,24900,0,0,1049,62041,0,0,340,7602,0,0;QS=3,0;MQSB=0.951002;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,101:3:0 0,12,141:4:0 +17 3211 . A 0 . DP=17;I16=11,6,0,0,645,24627,0,0,989,58441,0,0,341,7611,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,9,106:3:0 0,12,140:4:0 +17 3212 . T 0 . DP=17;I16=10,6,0,0,575,21295,0,0,960,57600,0,0,316,6964,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,222:9:0 0,9,100:3:0 0,12,144:4:0 +17 3213 . A 0 . DP=17;I16=10,6,0,0,597,22631,0,0,960,57600,0,0,316,6962,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,9,117:3:0 0,12,138:4:0 +17 3214 . G 0 . DP=17;I16=11,6,0,0,615,23103,0,0,989,58441,0,0,341,7605,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,9,110:3:0 0,12,134:4:0 +17 3215 . G 0 . DP=17;I16=11,6,0,0,591,21523,0,0,989,58441,0,0,340,7592,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,30,241:10:0 0,9,93:3:0 0,12,128:4:0 +17 3216 . C 0 . DP=17;I16=11,6,0,0,623,23303,0,0,989,58441,0,0,339,7597,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,30,242:10:0 0,9,94:3:0 0,12,138:4:0 +17 3217 . C 0 . DP=17;I16=11,6,0,0,570,19896,0,0,989,58441,0,0,337,7569,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,30,236:10:0 0,9,84:3:0 0,12,123:4:0 +17 3218 . G C, 0 . DP=18;I16=10,7,1,0,547,18185,29,841,1020,61200,29,841,310,6932,24,576;QS=2.91667,0.0833333,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.951002;BQB=1;MQ0F=0 PL:DP:DV 0,4,202,30,205,221:11:1 0,9,96,9,96,96:3:0 0,12,112,12,112,112:4:0 +17 3219 . G A, 0 . DP=18;I16=10,7,1,0,606,22158,19,361,1020,61200,29,841,308,6888,23,529;QS=2.94837,0.0516304,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.951002;BQB=1;MQ0F=0 PL:DP:DV 0,14,234,30,237,243:11:1 0,9,107,9,107,107:3:0 0,12,126,12,126,126:4:0 +17 3220 . G 0 . DP=18;I16=11,7,0,0,631,22827,0,0,1049,62041,0,0,326,7248,0,0;QS=3,0;MQSB=0.951002;MQ0F=0 PL:DP:DV 0,33,252:11:0 0,9,112:3:0 0,12,126:4:0 +17 3221 . C 0 . DP=17;I16=9,7,0,0,598,22586,0,0,960,57600,0,0,301,6659,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,9,103:3:0 0,12,139:4:0 +17 3222 . A 0 . DP=17;I16=10,7,0,0,623,23037,0,0,989,58441,0,0,318,6972,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,100:3:0 0,12,133:4:0 +17 3223 . C 0 . DP=17;I16=10,7,0,0,611,22603,0,0,989,58441,0,0,312,6764,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,96:3:0 0,12,132:4:0 +17 3224 . A 0 . DP=16;I16=10,6,0,0,609,23381,0,0,929,54841,0,0,307,6575,0,0;QS=3,0;MQSB=0.948436;MQ0F=0 PL:DP:DV 0,27,238:9:0 0,9,97:3:0 0,12,141:4:0 +17 3225 . G 0 . DP=17;I16=11,6,0,0,604,22692,0,0,989,58441,0,0,302,6404,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,27,247:9:0 0,12,108:4:0 0,12,134:4:0 +17 3226 . T 0 . DP=18;I16=11,6,0,0,582,20466,0,0,1020,61200,0,0,282,5996,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,224:9:0 0,12,112:4:0 0,12,131:4:0 +17 3227 . G 0 . DP=18;I16=12,5,0,0,618,23008,0,0,989,58441,0,0,270,5496,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,91:3:0 0,12,125:4:0 +17 3228 . G 0 . DP=18;I16=11,6,0,0,611,22581,0,0,1020,61200,0,0,278,5816,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,248:9:0 0,12,118:4:0 0,12,121:4:0 +17 3229 . C 0 . DP=19;I16=12,7,0,0,686,25394,0,0,1109,65641,0,0,289,5925,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,118:4:0 0,12,126:4:0 +17 3230 . T 0 . DP=19;I16=12,6,0,0,669,25441,0,0,1049,62041,0,0,261,5187,0,0;QS=3,0;MQSB=0.961295;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,107:3:0 0,12,139:4:0 +17 3231 . C 0 . DP=19;I16=12,7,0,0,682,25046,0,0,1109,65641,0,0,283,5725,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,112:4:0 0,12,128:4:0 +17 3232 . A 0 . DP=19;I16=11,7,0,0,597,20779,0,0,1080,64800,0,0,270,5564,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,229:10:0 0,12,117:4:0 0,12,132:4:0 +17 3233 . C 0 . DP=19;I16=12,7,0,0,573,18239,0,0,1109,65641,0,0,277,5629,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,33,238:11:0 0,12,91:4:0 0,12,110:4:0 +17 3234 . G T, 0 . DP=19;I16=10,6,1,0,511,17305,22,484,960,57600,29,841,233,4849,8,64;QS=2.93855,0.0614525,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.955563;BQB=1;MQ0F=0 PL:DP:DV 0,11,222,30,225,234:11:1 0,6,63,6,63,63:2:0 0,12,100,12,100,100:4:0 +17 3235 . C 0 . DP=18;I16=12,6,0,0,625,22649,0,0,1049,62041,0,0,274,5582,0,0;QS=3,0;MQSB=0.961295;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,12,119:4:0 0,12,123:4:0 +17 3236 . C 0 . DP=18;I16=12,6,0,0,668,25124,0,0,1049,62041,0,0,273,5567,0,0;QS=3,0;MQSB=0.961295;MQ0F=0 PL:DP:DV 0,30,244:10:0 0,12,137:4:0 0,12,134:4:0 +17 3237 . T 0 . DP=17;I16=11,6,0,0,589,21235,0,0,989,58441,0,0,273,5573,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,27,230:9:0 0,12,102:4:0 0,12,136:4:0 +17 3238 . G 0 . DP=17;I16=11,6,0,0,609,22539,0,0,989,58441,0,0,273,5599,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,27,243:9:0 0,12,104:4:0 0,12,129:4:0 +17 3239 . T 0 . DP=17;I16=11,6,0,0,574,20204,0,0,989,58441,0,0,273,5645,0,0;QS=3,0;MQSB=0.955563;MQ0F=0 PL:DP:DV 0,27,220:9:0 0,12,107:4:0 0,12,131:4:0 +17 3240 . A 0 . DP=19;I16=12,7,0,0,624,21552,0,0,1109,65641,0,0,273,5711,0,0;QS=3,0;MQSB=0.957193;MQ0F=0 PL:DP:DV 0,33,248:11:0 0,12,101:4:0 0,12,132:4:0 +17 3241 . A 0 . DP=19;I16=11,6,0,0,619,23121,0,0,1020,61200,0,0,249,5173,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,9,96:3:0 0,12,143:4:0 +17 3242 . T 0 . DP=19;I16=12,7,0,0,655,23279,0,0,1140,68400,0,0,277,5911,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,12,104:4:0 0,15,152:5:0 +17 3243 . C 0 . DP=19;I16=12,7,0,0,682,25216,0,0,1140,68400,0,0,281,6047,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,111:4:0 0,15,148:5:0 +17 3244 . C 0 . DP=18;I16=11,6,0,0,587,21119,0,0,1020,61200,0,0,281,6139,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,12,116:4:0 0,15,142:5:0 +17 3245 . C 0 . DP=17;I16=10,7,0,0,631,23851,0,0,1020,61200,0,0,290,6282,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,12,126:4:0 0,12,131:4:0 +17 3246 . A 0 . DP=17;I16=10,7,0,0,646,24716,0,0,1020,61200,0,0,295,6427,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,12,129:4:0 0,12,139:4:0 +17 3247 . G 0 . DP=17;I16=10,7,0,0,606,22554,0,0,1020,61200,0,0,300,6590,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,12,92:4:0 0,12,133:4:0 +17 3248 . C 0 . DP=16;I16=10,6,0,0,603,23115,0,0,960,57600,0,0,306,6770,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,9,99:3:0 0,12,132:4:0 +17 3249 . C 0 . DP=16;I16=10,6,0,0,587,21913,0,0,960,57600,0,0,311,6917,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,246:9:0 0,9,99:3:0 0,12,133:4:0 +17 3250 . C 0 . DP=16;I16=10,6,0,0,616,24080,0,0,960,57600,0,0,316,7082,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,9,95:3:0 0,12,137:4:0 +17 3251 . T 0 . DP=16;I16=10,6,0,0,585,22193,0,0,960,57600,0,0,319,7165,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,9,104:3:0 0,12,135:4:0 +17 3252 . T 0 . DP=16;I16=10,6,0,0,553,19781,0,0,960,57600,0,0,321,7215,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,9,84:3:0 0,12,126:4:0 +17 3253 . T 0 . DP=16;I16=10,6,0,0,589,21933,0,0,960,57600,0,0,323,7281,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,245:9:0 0,9,102:3:0 0,12,132:4:0 +17 3254 . G 0 . DP=17;I16=10,7,0,0,631,23737,0,0,1020,61200,0,0,325,7363,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,9,100:3:0 0,15,154:5:0 +17 3255 . G 0 . DP=16;I16=9,7,0,0,554,20088,0,0,960,57600,0,0,328,7410,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,243:9:0 0,9,93:3:0 0,12,120:4:0 +17 3256 . G 0 . DP=16;I16=8,7,0,0,571,21985,0,0,900,54000,0,0,306,6846,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,255:9:0 0,6,62:2:0 0,12,142:4:0 +17 3257 . A 0 . DP=16;I16=9,7,0,0,585,21881,0,0,960,57600,0,0,334,7546,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,243:9:0 0,9,94:3:0 0,12,144:4:0 +17 3258 . G 0 . DP=17;I16=9,8,0,0,647,25407,0,0,1020,61200,0,0,337,7635,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,81:3:0 0,12,146:4:0 +17 3259 . G 0 . DP=17;I16=9,8,0,0,605,22237,0,0,1020,61200,0,0,341,7739,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,9,79:3:0 0,12,139:4:0 +17 3260 . C 0 . DP=17;I16=9,7,0,0,616,23908,0,0,960,57600,0,0,319,7183,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,6,64:2:0 0,12,133:4:0 +17 3261 . C 0 . DP=18;I16=9,9,0,0,655,24475,0,0,1080,64800,0,0,347,7891,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,90:3:0 0,12,138:4:0 +17 3262 . A 0 . DP=19;I16=10,9,0,0,712,27036,0,0,1140,68400,0,0,351,7989,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,123:4:0 0,12,148:4:0 +17 3263 . G 0 . DP=19;I16=10,9,0,0,715,27317,0,0,1140,68400,0,0,356,8104,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,116:4:0 0,12,146:4:0 +17 3264 . G 0 . DP=19;I16=10,9,0,0,676,24734,0,0,1140,68400,0,0,361,8237,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,93:4:0 0,12,143:4:0 +17 3265 . G 0 . DP=19;I16=10,9,0,0,701,26199,0,0,1140,68400,0,0,365,8339,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,109:4:0 0,12,137:4:0 +17 3266 . T 0 . DP=19;I16=9,9,0,0,597,20769,0,0,1080,64800,0,0,357,8229,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,82:4:0 0,9,113:3:0 +17 3267 . G 0 . DP=19;I16=10,9,0,0,659,24285,0,0,1140,68400,0,0,367,8299,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,76:4:0 0,12,133:4:0 +17 3268 . G 0 . DP=19;I16=10,9,0,0,668,24306,0,0,1140,68400,0,0,367,8255,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,92:4:0 0,12,142:4:0 +17 3269 . G 0 . DP=19;I16=10,9,0,0,714,27122,0,0,1140,68400,0,0,367,8227,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,115:4:0 0,12,137:4:0 +17 3270 . T 0 . DP=20;I16=10,9,0,0,606,20364,0,0,1140,68400,0,0,361,8141,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,251:11:0 0,12,83:4:0 0,12,136:4:0 +17 3271 . G 0 . DP=19;I16=10,9,0,0,709,26993,0,0,1140,68400,0,0,362,8108,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,100:4:0 0,12,143:4:0 +17 3272 . G 0 . DP=19;I16=10,9,0,0,672,24398,0,0,1140,68400,0,0,363,8093,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,97:4:0 0,12,140:4:0 +17 3273 . A 0 . DP=20;I16=10,10,0,0,735,27355,0,0,1200,72000,0,0,363,8047,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,153:5:0 0,12,147:4:0 +17 3274 . T 0 . DP=19;I16=9,10,0,0,699,26089,0,0,1140,68400,0,0,365,8021,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,142:5:0 0,12,149:4:0 +17 3275 . C 0 . DP=19;I16=9,10,0,0,727,28197,0,0,1140,68400,0,0,367,8015,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,137:5:0 0,12,139:4:0 +17 3276 . A 0 . DP=19;I16=9,10,0,0,681,25123,0,0,1140,68400,0,0,369,8029,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,15,150:5:0 0,12,141:4:0 +17 3277 . C 0 . DP=19;I16=9,10,0,0,733,28485,0,0,1140,68400,0,0,371,8063,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,153:5:0 0,12,146:4:0 +17 3278 . T 0 . DP=19;I16=9,10,0,0,737,28901,0,0,1140,68400,0,0,373,8117,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,168:5:0 0,12,153:4:0 +17 3279 . T 0 . DP=19;I16=9,10,0,0,714,27132,0,0,1140,68400,0,0,375,8191,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,148:5:0 0,12,150:4:0 +17 3280 . G 0 . DP=20;I16=9,11,0,0,758,29178,0,0,1200,72000,0,0,376,8234,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,143:5:0 0,12,146:4:0 +17 3281 . A 0 . DP=21;I16=10,11,0,0,822,32654,0,0,1260,75600,0,0,378,8296,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,179:6:0 0,12,157:4:0 +17 3282 . G 0 . DP=21;I16=10,11,0,0,815,32059,0,0,1260,75600,0,0,381,8379,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,173:6:0 0,12,150:4:0 +17 3283 . G 0 . DP=21;I16=10,11,0,0,790,30110,0,0,1260,75600,0,0,384,8484,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,161:6:0 0,12,146:4:0 +17 3284 . T 0 . DP=21;I16=10,11,0,0,748,27628,0,0,1260,75600,0,0,385,8511,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,155:6:0 0,12,146:4:0 +17 3285 . C 0 . DP=21;I16=10,11,0,0,776,29442,0,0,1260,75600,0,0,386,8560,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,169:6:0 0,12,143:4:0 +17 3286 . A 0 . DP=21;I16=10,11,0,0,826,32732,0,0,1260,75600,0,0,387,8631,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,187:6:0 0,12,153:4:0 +17 3287 . G 0 . DP=21;I16=10,11,0,0,804,31448,0,0,1260,75600,0,0,387,8673,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,164:6:0 0,12,150:4:0 +17 3288 . G 0 . DP=22;I16=10,11,0,0,754,27862,0,0,1260,75600,0,0,379,8635,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,141:5:0 0,15,164:5:0 +17 3289 . A 0 . DP=24;I16=13,11,0,0,897,34439,0,0,1440,86400,0,0,386,8714,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,166:6:0 0,15,178:5:0 +17 3290 . G 0 . DP=23;I16=12,10,0,0,832,31964,0,0,1320,79200,0,0,380,8684,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,112:4:0 0,15,168:5:0 +17 3291 . T 0 . DP=22;I16=11,9,0,0,707,25481,0,0,1200,72000,0,0,358,8112,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,9,95:3:0 0,15,168:5:0 +17 3292 . T 0 . DP=22;I16=13,9,0,0,783,28439,0,0,1320,79200,0,0,397,8929,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,127:5:0 0,15,164:5:0 +17 3293 . C 0 . DP=22;I16=13,9,0,0,852,33430,0,0,1320,79200,0,0,400,8992,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,136:5:0 0,15,170:5:0 +17 3294 . A 0 . DP=22;I16=13,9,0,0,818,30684,0,0,1320,79200,0,0,403,9077,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,145:5:0 0,15,162:5:0 +17 3295 . A 0 . DP=22;I16=14,8,0,0,820,31004,0,0,1320,79200,0,0,407,9183,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,140:5:0 0,12,143:4:0 +17 3296 . G 0 . DP=22;I16=14,8,0,0,837,32209,0,0,1320,79200,0,0,411,9259,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,133:5:0 0,12,140:4:0 +17 3297 . A 0 . DP=22;I16=14,8,0,0,787,28771,0,0,1320,79200,0,0,415,9355,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,134:5:0 0,12,140:4:0 +17 3298 . C 0 . DP=22;I16=13,9,0,0,826,31506,0,0,1320,79200,0,0,420,9470,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,113:4:0 0,12,135:4:0 +17 3299 . C 0 . DP=22;I16=13,9,0,0,857,33829,0,0,1320,79200,0,0,425,9553,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,117:4:0 0,12,140:4:0 +17 3300 . A 0 . DP=22;I16=13,9,0,0,861,33855,0,0,1320,79200,0,0,430,9654,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,134:4:0 0,12,144:4:0 +17 3301 . G 0 . DP=22;I16=13,9,0,0,869,34495,0,0,1320,79200,0,0,433,9675,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,131:4:0 0,12,141:4:0 +17 3302 . C 0 . DP=23;I16=14,9,0,0,863,32885,0,0,1380,82800,0,0,436,9718,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,115:4:0 0,15,155:5:0 +17 3303 . C 0 . DP=23;I16=14,9,0,0,887,34451,0,0,1380,82800,0,0,440,9784,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,125:4:0 0,15,153:5:0 +17 3304 . T 0 . DP=23;I16=14,9,0,0,886,34388,0,0,1380,82800,0,0,443,9825,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,134:4:0 0,15,167:5:0 +17 3305 . G 0 . DP=23;I16=14,9,0,0,878,33846,0,0,1380,82800,0,0,446,9892,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,119:4:0 0,15,151:5:0 +17 3306 . G 0 . DP=23;I16=14,9,0,0,886,34386,0,0,1380,82800,0,0,448,9934,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,127:4:0 0,15,150:5:0 +17 3307 . C 0 . DP=23;I16=14,8,0,0,812,30814,0,0,1320,79200,0,0,428,9508,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,116:4:0 0,15,153:5:0 +17 3308 . C 0 . DP=23;I16=14,9,0,0,835,31367,0,0,1380,82800,0,0,450,9986,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,118:4:0 0,15,151:5:0 +17 3309 . A 0 . DP=23;I16=14,9,0,0,875,33541,0,0,1380,82800,0,0,451,9995,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,128:4:0 0,15,162:5:0 +17 3310 . A 0 . DP=24;I16=15,9,0,0,882,32950,0,0,1440,86400,0,0,453,10027,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,152:5:0 0,15,164:5:0 +17 3311 . C 0 . DP=24;I16=15,9,0,0,913,35161,0,0,1440,86400,0,0,456,10084,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,145:5:0 0,15,157:5:0 +17 3312 . A 0 . DP=26;I16=16,9,0,0,950,36336,0,0,1500,90000,0,0,459,10167,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,153:5:0 0,15,160:5:0 +17 3313 . T 0 . DP=26;I16=16,10,0,0,987,37617,0,0,1560,93600,0,0,488,10902,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,180:6:0 0,15,161:5:0 +17 3314 . G 0 . DP=26;I16=16,10,0,0,1007,39401,0,0,1560,93600,0,0,491,10989,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,171:6:0 0,15,161:5:0 +17 3315 . G 0 . DP=26;I16=15,10,0,0,945,36073,0,0,1500,90000,0,0,484,10866,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,172:6:0 0,15,159:5:0 +17 3316 . T 0 . DP=26;I16=15,10,0,0,853,29881,0,0,1500,90000,0,0,464,10216,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,157:6:0 0,12,122:4:0 +17 3317 . G 0 . DP=27;I16=16,11,0,0,997,37431,0,0,1620,97200,0,0,488,10806,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,164:6:0 0,18,167:6:0 +17 3318 . A 0 . DP=26;I16=15,10,0,0,904,33212,0,0,1500,90000,0,0,481,10699,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,155:5:0 0,18,185:6:0 +17 3319 . A 0 . DP=25;I16=15,10,0,0,912,34090,0,0,1500,90000,0,0,482,10682,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,139:5:0 0,18,188:6:0 +17 3320 . A 0 . DP=25;I16=15,10,0,0,888,32722,0,0,1500,90000,0,0,483,10691,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,133:5:0 0,18,178:6:0 +17 3321 . C 0 . DP=25;I16=14,10,0,0,900,34142,0,0,1440,86400,0,0,471,10531,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,157:5:0 0,18,186:6:0 +17 3322 . C 0 . DP=25;I16=15,10,0,0,980,38582,0,0,1500,90000,0,0,483,10683,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,164:5:0 0,18,198:6:0 +17 3323 . C 0 . DP=25;I16=15,10,0,0,922,34948,0,0,1500,90000,0,0,483,10715,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,146:5:0 0,18,201:6:0 +17 3324 . C 0 . DP=25;I16=15,10,0,0,869,31271,0,0,1500,90000,0,0,482,10720,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,142:5:0 0,18,186:6:0 +17 3325 . G 0 . DP=25;I16=15,10,0,0,827,28293,0,0,1500,90000,0,0,481,10747,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,134:5:0 0,18,163:6:0 +17 3326 . T 0 . DP=24;I16=13,10,0,0,842,31362,0,0,1380,82800,0,0,464,10506,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,150:5:0 0,18,186:6:0 +17 3327 . C 0 . DP=24;I16=14,10,0,0,938,37076,0,0,1440,86400,0,0,481,10863,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,154:5:0 0,18,190:6:0 +17 3328 . T 0 . DP=25;I16=15,10,0,0,959,37033,0,0,1500,90000,0,0,480,10900,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,163:5:0 0,21,213:7:0 +17 3329 . A 0 . DP=24;I16=15,9,0,0,888,33082,0,0,1440,86400,0,0,481,10955,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,149:5:0 0,21,207:7:0 +17 3330 . C 0 . DP=25;I16=16,9,0,0,954,37064,0,0,1500,90000,0,0,481,10979,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,168:5:0 0,21,203:7:0 +17 3331 . T 0 . DP=25;I16=16,9,0,0,960,37332,0,0,1500,90000,0,0,482,11024,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,165:5:0 0,21,224:7:0 +17 3332 . A 0 . DP=25;I16=16,9,0,0,933,35065,0,0,1500,90000,0,0,483,11091,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,165:5:0 0,21,211:7:0 +17 3333 . A 0 . DP=26;I16=16,10,0,0,976,37344,0,0,1560,93600,0,0,483,11131,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,166:5:0 0,24,241:8:0 +17 3334 . A 0 . DP=25;I16=15,10,0,0,972,38210,0,0,1500,90000,0,0,485,11195,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,168:5:0 0,24,241:8:0 +17 3335 . A 0 . DP=25;I16=15,10,0,0,970,38200,0,0,1500,90000,0,0,486,11232,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,170:5:0 0,24,239:8:0 +17 3336 . A 0 . DP=25;I16=15,10,0,0,929,35277,0,0,1500,90000,0,0,485,11191,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,166:5:0 0,24,232:8:0 +17 3337 . T 0 . DP=25;I16=15,10,0,0,902,32856,0,0,1500,90000,0,0,484,11172,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,157:5:0 0,24,224:8:0 +17 3338 . A 0 . DP=25;I16=15,10,0,0,892,32056,0,0,1500,90000,0,0,481,11075,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,153:5:0 0,24,214:8:0 +17 3339 . C 0 . DP=25;I16=15,10,0,0,964,37444,0,0,1500,90000,0,0,478,11000,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,167:5:0 0,24,232:8:0 +17 3340 . A 0 . DP=23;I16=14,9,0,0,890,34616,0,0,1380,82800,0,0,477,10945,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,173:5:0 0,24,233:8:0 +17 3341 . A 0 . DP=23;I16=14,9,0,0,885,34459,0,0,1380,82800,0,0,476,10908,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,167:5:0 0,24,238:8:0 +17 3342 . A 0 . DP=23;I16=14,9,0,0,862,33262,0,0,1380,82800,0,0,475,10889,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,170:5:0 0,24,240:8:0 +17 3343 . A 0 . DP=22;I16=13,9,0,0,866,34280,0,0,1320,79200,0,0,474,10836,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,173:5:0 0,21,231:7:0 +17 3344 . A 0 . DP=22;I16=13,9,0,0,859,33731,0,0,1320,79200,0,0,473,10797,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,173:5:0 0,21,226:7:0 +17 3345 . T 0 . DP=22;I16=13,9,0,0,822,31100,0,0,1320,79200,0,0,472,10772,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,254:10:0 0,15,159:5:0 0,21,220:7:0 +17 3346 . T 0 . DP=22;I16=13,9,0,0,847,32679,0,0,1320,79200,0,0,470,10712,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,168:5:0 0,21,221:7:0 +17 3347 . A 0 . DP=23;I16=14,9,0,0,888,34650,0,0,1380,82800,0,0,468,10668,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,185:6:0 0,21,227:7:0 +17 3348 . G 0 . DP=23;I16=14,9,0,0,873,33609,0,0,1380,82800,0,0,467,10641,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,171:6:0 0,21,219:7:0 +17 3349 . C 0 . DP=24;I16=14,9,0,0,815,29785,0,0,1380,82800,0,0,465,10583,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,166:6:0 0,21,205:7:0 +17 3350 . C 0 . DP=24;I16=14,10,0,0,939,37249,0,0,1440,86400,0,0,464,10546,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,209:7:0 0,21,220:7:0 +17 3351 . T 0 . DP=24;I16=14,10,0,0,943,37255,0,0,1440,86400,0,0,463,10531,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,210:7:0 0,21,228:7:0 +17 3352 . G 0 . DP=24;I16=14,10,0,0,887,33267,0,0,1440,86400,0,0,462,10538,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,192:7:0 0,21,214:7:0 +17 3353 . G 0 . DP=24;I16=14,10,0,0,864,32092,0,0,1440,86400,0,0,461,10567,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,190:7:0 0,21,214:7:0 +17 3354 . C 0 . DP=24;I16=14,10,0,0,848,30714,0,0,1440,86400,0,0,459,10567,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,178:7:0 0,21,209:7:0 +17 3355 . G 0 . DP=23;I16=14,9,0,0,738,24386,0,0,1380,82800,0,0,457,10537,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,232:10:0 0,21,170:7:0 0,18,166:6:0 +17 3356 . T 0 . DP=23;I16=14,9,0,0,847,31689,0,0,1380,82800,0,0,454,10476,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,191:7:0 0,18,195:6:0 +17 3357 . G 0 . DP=23;I16=14,9,0,0,863,32919,0,0,1380,82800,0,0,449,10335,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,193:7:0 0,18,192:6:0 +17 3358 . G 0 . DP=22;I16=14,8,0,0,810,30184,0,0,1320,79200,0,0,445,10215,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,21,200:7:0 0,18,187:6:0 +17 3359 . T 0 . DP=23;I16=13,8,0,0,743,26737,0,0,1260,75600,0,0,404,9318,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,21,194:7:0 0,15,162:5:0 +17 3360 . G 0 . DP=23;I16=15,8,0,0,822,30058,0,0,1380,82800,0,0,436,9932,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,186:7:0 0,18,175:6:0 +17 3361 . G 0 . DP=22;I16=15,7,0,0,751,26793,0,0,1320,79200,0,0,433,9819,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,218:9:0 0,21,187:7:0 0,18,175:6:0 +17 3362 . C 0 . DP=22;I16=15,7,0,0,768,27462,0,0,1320,79200,0,0,430,9724,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,230:9:0 0,21,178:7:0 0,18,173:6:0 +17 3363 . G 0 . DP=21;I16=14,7,0,0,662,21572,0,0,1260,75600,0,0,428,9646,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,194:9:0 0,18,155:6:0 0,18,161:6:0 +17 3364 . C 0 . DP=21;I16=14,7,0,0,818,32184,0,0,1260,75600,0,0,423,9437,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,18,191:6:0 0,18,194:6:0 +17 3365 . A 0 . DP=21;I16=14,7,0,0,791,29983,0,0,1260,75600,0,0,418,9250,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,226:9:0 0,18,186:6:0 0,18,190:6:0 +17 3366 . T 0 . DP=21;I16=14,7,0,0,759,28053,0,0,1260,75600,0,0,413,9085,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,221:9:0 0,18,185:6:0 0,18,177:6:0 +17 3367 . G 0 . DP=21;I16=14,7,0,0,767,28539,0,0,1260,75600,0,0,408,8942,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,235:9:0 0,18,185:6:0 0,18,169:6:0 +17 3368 . C 0 . DP=21;I16=14,7,0,0,807,31329,0,0,1260,75600,0,0,403,8821,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,245:9:0 0,18,181:6:0 0,18,189:6:0 +17 3369 . C 0 . DP=21;I16=14,7,0,0,789,30271,0,0,1260,75600,0,0,398,8722,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,18,186:6:0 0,18,193:6:0 +17 3370 . T 0 . DP=21;I16=13,7,0,0,798,31960,0,0,1200,72000,0,0,392,8596,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,239:9:0 0,18,201:6:0 0,15,178:5:0 +17 3371 . G 0 . DP=20;I16=13,7,0,0,739,27875,0,0,1200,72000,0,0,387,8493,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,18,173:6:0 0,15,169:5:0 +17 3372 . T 0 . DP=20;I16=13,6,0,0,693,25677,0,0,1140,68400,0,0,359,7883,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,220:9:0 0,15,154:5:0 0,15,167:5:0 +17 3373 . A 0 . DP=20;I16=13,7,0,0,729,27019,0,0,1200,72000,0,0,375,8253,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,226:9:0 0,18,162:6:0 0,15,174:5:0 +17 3374 . A 0 . DP=19;I16=13,6,0,0,719,27437,0,0,1140,68400,0,0,369,8115,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,225:9:0 0,15,167:5:0 0,15,164:5:0 +17 3375 . T 0 . DP=20;I16=12,6,0,0,683,26039,0,0,1080,64800,0,0,337,7321,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,15,155:5:0 0,15,172:5:0 +17 3376 . C 0 . DP=20;I16=13,7,0,0,739,27867,0,0,1200,72000,0,0,356,7796,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,254:10:0 0,15,146:5:0 0,15,173:5:0 +17 3377 . C 0 . DP=20;I16=13,7,0,0,741,27905,0,0,1200,72000,0,0,350,7666,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,15,149:5:0 0,15,173:5:0 +17 3378 . C 0 . DP=20;I16=13,7,0,0,775,30179,0,0,1200,72000,0,0,343,7507,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,15,161:5:0 0,15,172:5:0 +17 3379 . A 0 . DP=20;I16=13,7,0,0,736,27530,0,0,1200,72000,0,0,336,7370,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,245:10:0 0,15,157:5:0 0,15,169:5:0 +17 3380 . G 0 . DP=19;I16=13,6,0,0,729,28249,0,0,1140,68400,0,0,330,7254,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,15,157:5:0 0,15,178:5:0 +17 3381 . C 0 . DP=19;I16=13,6,0,0,742,29288,0,0,1140,68400,0,0,324,7158,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,241:9:0 0,15,155:5:0 0,15,178:5:0 +17 3382 . T 0 . DP=17;I16=12,5,0,0,649,25245,0,0,1020,61200,0,0,320,7080,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,222:9:0 0,9,105:3:0 0,15,184:5:0 +17 3383 . A 0 . DP=17;I16=12,4,0,0,556,19808,0,0,960,57600,0,0,291,6393,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,196:9:0 0,6,71:2:0 0,15,167:5:0 +17 3384 . C 0 . DP=19;I16=14,5,0,0,701,26181,0,0,1140,68400,0,0,311,6923,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,235:10:0 0,9,98:3:0 0,18,187:6:0 +17 3385 . T 0 . DP=19;I16=14,5,0,0,730,28456,0,0,1140,68400,0,0,307,6797,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,237:10:0 0,9,109:3:0 0,18,195:6:0 +17 3386 . T 0 . DP=19;I16=14,5,0,0,642,22450,0,0,1140,68400,0,0,302,6642,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,197:10:0 0,9,104:3:0 0,18,188:6:0 +17 3387 . G 0 . DP=20;I16=14,6,0,0,723,26761,0,0,1200,72000,0,0,296,6460,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,230:10:0 0,9,105:3:0 0,21,210:7:0 +17 3388 . G 0 . DP=20;I16=14,6,0,0,705,25891,0,0,1200,72000,0,0,291,6303,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,225:10:0 0,9,109:3:0 0,21,202:7:0 +17 3389 . G 0 . DP=18;I16=10,7,0,0,617,22635,0,0,1020,61200,0,0,270,5808,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,190:7:0 0,9,105:3:0 0,21,207:7:0 +17 3390 . A 0 . DP=18;I16=11,7,0,0,631,22681,0,0,1080,64800,0,0,288,6056,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,200:8:0 0,9,105:3:0 0,21,198:7:0 +17 3391 . A 0 . DP=18;I16=11,7,0,0,663,24951,0,0,1080,64800,0,0,287,5965,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,192:8:0 0,9,113:3:0 0,21,224:7:0 +17 3392 . G 0 . DP=18;I16=11,7,0,0,666,25104,0,0,1080,64800,0,0,286,5896,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,211:8:0 0,9,103:3:0 0,21,216:7:0 +17 3393 . C 0 . DP=18;I16=11,7,0,0,686,26472,0,0,1080,64800,0,0,284,5800,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,222:8:0 0,9,106:3:0 0,21,214:7:0 +17 3394 . T 0 . DP=18;I16=11,7,0,0,699,27481,0,0,1080,64800,0,0,282,5728,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,219:8:0 0,9,114:3:0 0,21,222:7:0 +17 3395 . G 0 . DP=17;I16=10,7,0,0,656,25512,0,0,1020,61200,0,0,281,5679,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,205:7:0 0,9,105:3:0 0,21,222:7:0 +17 3396 . A 0 . DP=17;I16=10,7,0,0,644,25446,0,0,1020,61200,0,0,280,5652,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,182:7:0 0,9,119:3:0 0,21,232:7:0 +17 3397 . G 0 . DP=17;I16=10,7,0,0,633,23895,0,0,1020,61200,0,0,279,5647,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,193:7:0 0,9,107:3:0 0,21,218:7:0 +17 3398 . G 0 . DP=16;I16=10,6,0,0,610,23380,0,0,960,57600,0,0,279,5663,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,170:6:0 0,9,110:3:0 0,21,215:7:0 +17 3399 . G 0 . DP=17;I16=10,6,0,0,585,21729,0,0,960,57600,0,0,270,5618,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,147:5:0 0,12,122:4:0 0,21,216:7:0 +17 3400 . A 0 . DP=17;I16=10,6,0,0,576,21400,0,0,960,57600,0,0,264,5500,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,136:5:0 0,12,131:4:0 0,21,213:7:0 +17 3401 . T 0 . DP=17;I16=11,6,0,0,605,22159,0,0,1020,61200,0,0,280,5784,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,146:6:0 0,12,131:4:0 0,21,216:7:0 +17 3402 . G 0 . DP=17;I16=11,6,0,0,638,24150,0,0,1020,61200,0,0,280,5832,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,172:6:0 0,12,130:4:0 0,21,213:7:0 +17 3403 . A 0 . DP=16;I16=9,6,0,0,579,22815,0,0,900,54000,0,0,276,5874,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,139:5:0 0,12,140:4:0 0,18,205:6:0 +17 3404 . G 0 . DP=16;I16=10,6,0,0,564,20652,0,0,960,57600,0,0,281,5935,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,148:6:0 0,12,131:4:0 0,18,186:6:0 +17 3405 . A 0 . DP=16;I16=10,6,0,0,560,20158,0,0,960,57600,0,0,281,5991,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,157:6:0 0,12,124:4:0 0,18,179:6:0 +17 3406 . A 0 . DP=16;I16=10,6,0,0,568,20556,0,0,960,57600,0,0,281,6067,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,150:6:0 0,12,129:4:0 0,18,186:6:0 +17 3407 . C 0 . DP=17;I16=11,6,0,0,591,21225,0,0,1020,61200,0,0,281,6163,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,178:7:0 0,12,106:4:0 0,18,183:6:0 +17 3408 . T 0 . DP=17;I16=11,6,0,0,632,23754,0,0,1020,61200,0,0,282,6280,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,177:7:0 0,12,133:4:0 0,18,189:6:0 +17 3409 . G 0 . DP=16;I16=10,6,0,0,599,22667,0,0,960,57600,0,0,283,6369,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,172:6:0 0,12,119:4:0 0,18,192:6:0 +17 3410 . C 0 . DP=16;I16=10,6,0,0,585,21685,0,0,960,57600,0,0,282,6378,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,174:6:0 0,12,126:4:0 0,18,176:6:0 +17 3411 . T 0 . DP=15;I16=9,6,0,0,578,22492,0,0,900,54000,0,0,282,6404,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,165:6:0 0,9,114:3:0 0,18,196:6:0 +17 3412 . T 0 . DP=15;I16=9,6,0,0,546,20202,0,0,900,54000,0,0,283,6445,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,148:5:0 0,12,120:4:0 0,18,189:6:0 +17 3413 . G 0 . DP=15;I16=9,6,0,0,559,21023,0,0,900,54000,0,0,283,6401,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,158:5:0 0,12,124:4:0 0,18,184:6:0 +17 3414 . A 0 . DP=15;I16=9,6,0,0,512,17878,0,0,900,54000,0,0,283,6373,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,148:5:0 0,12,116:4:0 0,18,166:6:0 +17 3415 . A 0 . DP=16;I16=9,7,0,0,544,19656,0,0,960,57600,0,0,282,6310,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,142:5:0 0,12,132:4:0 0,21,179:7:0 +17 3416 . C 0 . DP=16;I16=9,7,0,0,562,20168,0,0,960,57600,0,0,282,6262,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,143:5:0 0,12,127:4:0 0,21,191:7:0 +17 3417 . C 0 . DP=16;I16=9,7,0,0,566,20666,0,0,960,57600,0,0,282,6230,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,147:5:0 0,12,126:4:0 0,21,192:7:0 +17 3418 . T 0 . DP=17;I16=10,5,0,0,557,21637,0,0,900,54000,0,0,268,5988,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,150:5:0 0,15,148:5:0 0,15,176:5:0 +17 3419 . G 0 . DP=17;I16=10,7,0,0,594,21642,0,0,1020,61200,0,0,310,6836,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,161:6:0 0,15,140:5:0 0,18,190:6:0 +17 3420 . G 0 . DP=17;I16=10,7,0,0,596,21580,0,0,1020,61200,0,0,312,6850,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,172:6:0 0,15,132:5:0 0,18,188:6:0 +17 3421 . G 0 . DP=18;I16=10,8,0,0,633,22781,0,0,1049,62041,0,0,314,6880,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,21,184:7:0 0,15,138:5:0 0,18,191:6:0 +17 3422 . A 0 . DP=18;I16=9,8,0,0,576,20954,0,0,989,58441,0,0,302,6702,0,0;QS=3,0;MQSB=0.91051;MQ0F=0 PL:DP:DV 0,18,167:6:0 0,15,130:5:0 0,18,188:6:0 +17 3423 . G 0 . DP=18;I16=9,9,0,0,651,24391,0,0,1049,62041,0,0,305,6747,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,21,200:7:0 0,15,149:5:0 0,18,183:6:0 +17 3424 . G 0 . DP=18;I16=8,8,0,0,555,20175,0,0,929,54841,0,0,275,6105,0,0;QS=3,0;MQSB=0.915545;MQ0F=0 PL:DP:DV 0,18,161:6:0 0,15,141:5:0 0,15,169:5:0 +17 3425 . C 0 . DP=18;I16=9,8,0,0,594,21676,0,0,1020,61200,0,0,307,6779,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,168:6:0 0,15,142:5:0 0,18,186:6:0 +17 3426 . A 0 . DP=18;I16=9,8,0,0,633,23967,0,0,1020,61200,0,0,308,6774,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,172:6:0 0,15,151:5:0 0,18,202:6:0 +17 3427 . G 0 . DP=18;I16=9,9,0,0,655,24639,0,0,1049,62041,0,0,315,6823,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,21,209:7:0 0,15,144:5:0 0,18,184:6:0 +17 3428 . A 0 . DP=18;I16=9,7,0,0,573,21235,0,0,960,57600,0,0,305,6793,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,158:5:0 0,15,147:5:0 0,18,178:6:0 +17 3429 . C 0 . DP=17;I16=8,9,0,0,516,16610,0,0,989,58441,0,0,320,6930,0,0;QS=3,0;MQSB=0.928603;MQ0F=0 PL:DP:DV 0,21,176:7:0 0,15,125:5:0 0,15,124:5:0 +17 3430 . G 0 . DP=18;I16=9,9,0,0,539,17155,0,0,1049,62041,0,0,323,7011,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,24,181:8:0 0,15,113:5:0 0,15,144:5:0 +17 3431 . T 0 . DP=18;I16=9,9,0,0,651,24101,0,0,1049,62041,0,0,327,7111,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,24,210:8:0 0,15,139:5:0 0,15,166:5:0 +17 3432 . T 0 . DP=18;I16=8,9,0,0,577,20601,0,0,989,58441,0,0,306,6606,0,0;QS=3,0;MQSB=0.928603;MQ0F=0 PL:DP:DV 0,21,162:7:0 0,15,144:5:0 0,15,165:5:0 +17 3433 . G 0 . DP=18;I16=9,9,0,0,623,22589,0,0,1049,62041,0,0,334,7320,0,0;QS=3,0;MQSB=0.924089;MQ0F=0 PL:DP:DV 0,24,199:8:0 0,15,138:5:0 0,15,164:5:0 +17 3434 . C 0 . DP=18;I16=10,7,0,0,582,20838,0,0,1020,61200,0,0,324,7208,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,208:8:0 0,15,130:5:0 0,12,137:4:0 +17 3435 . A 0 . DP=18;I16=10,8,0,0,595,21619,0,0,1049,62041,0,0,341,7453,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,27,185:9:0 0,15,150:5:0 0,12,151:4:0 +17 3436 . G 0 . DP=18;I16=10,8,0,0,617,22277,0,0,1049,62041,0,0,345,7549,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,27,218:9:0 0,15,146:5:0 0,12,133:4:0 +17 3437 . T G, 0 . DP=18;I16=10,7,0,1,594,21168,16,256,1020,61200,29,841,333,7409,16,256;QS=2.94286,0.0571429,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.906029;BQB=1;MQ0F=0 PL:DP:DV 0,11,188,24,191,195:9:1 0,15,148,15,148,148:5:0 0,12,132,12,132,132:4:0 +17 3438 . G 0 . DP=18;I16=10,7,0,0,622,23296,0,0,1020,61200,0,0,335,7461,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,215:8:0 0,15,152:5:0 0,12,140:4:0 +17 3439 . A 0 . DP=18;I16=10,8,0,0,619,22965,0,0,1049,62041,0,0,355,7853,0,0;QS=3,0;MQSB=0.906029;MQ0F=0 PL:DP:DV 0,27,215:9:0 0,15,153:5:0 0,12,132:4:0 +17 3440 . G 0 . DP=18;I16=10,7,0,0,610,22660,0,0,1020,61200,0,0,339,7613,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,221:8:0 0,15,143:5:0 0,12,131:4:0 +17 3441 . C 0 . DP=18;I16=10,6,0,0,585,22165,0,0,960,57600,0,0,315,7037,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,226:8:0 0,15,140:5:0 0,9,115:3:0 +17 3442 . T 0 . DP=20;I16=11,9,0,0,670,24716,0,0,1138,66482,0,0,362,8166,0,0;QS=3,0;MQSB=0.997118;MQ0F=0 PL:DP:DV 0,33,248:11:0 0,15,143:5:0 0,12,128:4:0 +17 3443 . G 0 . DP=20;I16=11,9,0,0,708,26092,0,0,1138,66482,0,0,366,8288,0,0;QS=3,0;MQSB=0.997118;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,143:5:0 0,12,137:4:0 +17 3444 . A 0 . DP=20;I16=11,9,0,0,698,25978,0,0,1138,66482,0,0,369,8379,0,0;QS=3,0;MQSB=0.997118;MQ0F=0 PL:DP:DV 0,33,244:11:0 0,15,161:5:0 0,12,131:4:0 +17 3445 . G 0 . DP=20;I16=11,9,0,0,718,26590,0,0,1138,66482,0,0,372,8488,0,0;QS=3,0;MQSB=0.997118;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,153:5:0 0,12,132:4:0 +17 3446 . A 0 . DP=20;I16=10,8,0,0,635,23323,0,0,1049,62041,0,0,325,7365,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,27,222:9:0 0,15,154:5:0 0,12,131:4:0 +17 3447 . T 0 . DP=20;I16=11,8,0,0,669,24331,0,0,1109,65641,0,0,352,8084,0,0;QS=3,0;MQSB=0.946915;MQ0F=0 PL:DP:DV 0,30,230:10:0 0,15,150:5:0 0,12,137:4:0 +17 3448 . C 0 . DP=19;I16=10,8,0,0,641,23693,0,0,1049,62041,0,0,355,8193,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,113:4:0 0,12,128:4:0 +17 3449 . A 0 . DP=19;I16=10,8,0,0,565,19185,0,0,1049,62041,0,0,357,8265,0,0;QS=3,0;MQSB=0.938795;MQ0F=0 PL:DP:DV 0,30,217:10:0 0,12,111:4:0 0,12,119:4:0 +17 3450 . C 0 . DP=18;I16=8,8,0,0,520,17846,0,0,898,52082,0,0,334,7674,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,30,229:10:0 0,6,70:2:0 0,12,106:4:0 +17 3451 . G 0 . DP=18;I16=10,7,0,0,528,17178,0,0,989,58441,0,0,361,8345,0,0;QS=3,0;MQSB=0.943335;MQ0F=0 PL:DP:DV 0,30,226:10:0 0,9,56:3:0 0,12,123:4:0 +17 3452 . C 0 . DP=18;I16=10,8,0,0,657,24597,0,0,1018,59282,0,0,388,9028,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,84:3:0 0,12,128:4:0 +17 3453 . C 0 . DP=18;I16=10,8,0,0,663,24951,0,0,1018,59282,0,0,390,9098,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,90:3:0 0,12,125:4:0 +17 3454 . A 0 . DP=18;I16=10,8,0,0,614,21898,0,0,1018,59282,0,0,392,9180,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,33,251:11:0 0,9,90:3:0 0,12,128:4:0 +17 3455 . C 0 . DP=18;I16=10,8,0,0,650,23968,0,0,1018,59282,0,0,394,9274,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,90:3:0 0,12,127:4:0 +17 3456 . T 0 . DP=18;I16=10,8,0,0,607,21961,0,0,1018,59282,0,0,395,9329,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,33,243:11:0 0,9,88:3:0 0,12,135:4:0 +17 3457 . G 0 . DP=18;I16=9,7,0,0,549,19861,0,0,898,52082,0,0,346,8144,0,0;QS=3,0;MQSB=0.994413;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,6,63:2:0 0,9,107:3:0 +17 3458 . C 0 . DP=18;I16=10,8,0,0,638,23236,0,0,1018,59282,0,0,397,9469,0,0;QS=3,0;MQSB=0.99606;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,81:3:0 0,12,125:4:0 +17 3459 . A C, 0 . DP=17;I16=9,7,0,1,520,18390,22,484,929,54841,29,841,372,8830,25,625;QS=2.92971,0.0702875,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.998843;BQB=1;MQ0F=0 PL:DP:DV 0,8,201,27,204,213:10:1 0,9,84,9,84,84:3:0 0,12,116,12,116,116:4:0 +17 3460 . C 0 . DP=17;I16=8,7,0,0,554,20952,0,0,869,51241,0,0,345,8103,0,0;QS=3,0;MQSB=0.921243;MQ0F=0 PL:DP:DV 0,27,244:9:0 0,6,65:2:0 0,12,131:4:0 +17 3461 . T 0 . DP=17;I16=9,7,0,0,591,22805,0,0,929,54841,0,0,368,8638,0,0;QS=3,0;MQSB=0.933674;MQ0F=0 PL:DP:DV 0,27,231:9:0 0,9,103:3:0 0,12,133:4:0 +17 3462 . C 0 . DP=18;I16=9,9,0,0,672,25486,0,0,1018,59282,0,0,391,9185,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,90:3:0 0,12,130:4:0 +17 3463 . C 0 . DP=18;I16=8,9,0,0,584,21458,0,0,958,55682,0,0,369,8671,0,0;QS=3,0;MQSB=0.998843;MQ0F=0 PL:DP:DV 0,30,244:10:0 0,9,86:3:0 0,12,132:4:0 +17 3464 . A 0 . DP=18;I16=9,9,0,0,628,23490,0,0,1018,59282,0,0,387,8973,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,244:11:0 0,9,96:3:0 0,12,142:4:0 +17 3465 . G 0 . DP=19;I16=9,9,0,0,642,24008,0,0,1018,59282,0,0,384,8842,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,91:3:0 0,12,135:4:0 +17 3466 . C 0 . DP=20;I16=9,10,0,0,682,25218,0,0,1047,60123,0,0,378,8588,0,0;QS=3,0;MQSB=0.904084;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,9,101:3:0 0,15,147:5:0 +17 3467 . C 0 . DP=20;I16=10,9,0,0,685,25919,0,0,1047,60123,0,0,397,9139,0,0;QS=3,0;MQSB=0.948064;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,12,115:4:0 0,15,154:5:0 +17 3468 . T 0 . DP=20;I16=10,9,0,0,672,25426,0,0,1047,60123,0,0,374,8410,0,0;QS=3,0;MQSB=0.948064;MQ0F=0 PL:DP:DV 0,30,246:10:0 0,12,126:4:0 0,15,164:5:0 +17 3469 . G 0 . DP=21;I16=10,11,0,0,788,30064,0,0,1167,67323,0,0,396,8924,0,0;QS=3,0;MQSB=0.914611;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,146:5:0 0,15,163:5:0 +17 3470 . G 0 . DP=22;I16=11,11,0,0,796,29754,0,0,1196,68164,0,0,393,8781,0,0;QS=3,0;MQSB=0.770381;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,131:5:0 0,15,161:5:0 +17 3471 . G 0 . DP=23;I16=12,11,0,0,801,29083,0,0,1256,71764,0,0,391,8657,0,0;QS=3,0;MQSB=0.811552;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,133:5:0 0,15,151:5:0 +17 3472 . C 0 . DP=23;I16=12,11,0,0,757,26535,0,0,1256,71764,0,0,390,8554,0,0;QS=3,0;MQSB=0.811552;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,145:5:0 0,15,136:5:0 +17 3473 . A 0 . DP=23;I16=11,11,0,0,777,28175,0,0,1196,68164,0,0,379,8373,0,0;QS=3,0;MQSB=0.770381;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,148:5:0 0,15,153:5:0 +17 3474 . A 0 . DP=23;I16=12,11,0,0,807,29181,0,0,1256,71764,0,0,388,8414,0,0;QS=3,0;MQSB=0.811552;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,150:5:0 0,15,155:5:0 +17 3475 . C 0 . DP=22;I16=12,10,0,0,737,25849,0,0,1196,68164,0,0,387,8327,0,0;QS=3,0;MQSB=0.838545;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,137:5:0 0,15,143:5:0 +17 3476 . A 0 . DP=22;I16=12,10,0,0,790,29312,0,0,1196,68164,0,0,386,8262,0,0;QS=3,0;MQSB=0.838545;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,149:5:0 0,15,154:5:0 +17 3477 . G 0 . DP=22;I16=11,10,0,0,755,28237,0,0,1136,64564,0,0,363,7735,0,0;QS=3,0;MQSB=0.799507;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,126:4:0 0,15,153:5:0 +17 3478 . A 0 . DP=25;I16=13,11,0,0,857,31637,0,0,1316,75364,0,0,384,8198,0,0;QS=3,0;MQSB=0.845496;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,167:6:0 0,18,190:6:0 +17 3479 . G 0 . DP=25;I16=12,10,0,0,783,28623,0,0,1227,70923,0,0,355,7701,0,0;QS=3,0;MQSB=0.613159;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,152:5:0 0,18,160:6:0 +17 3480 . T 0 . DP=25;I16=13,11,0,0,788,27124,0,0,1316,75364,0,0,393,8531,0,0;QS=3,0;MQSB=0.845496;MQ0F=0 PL:DP:DV 0,33,249:11:0 0,21,182:7:0 0,18,155:6:0 +17 3481 . A 0 . DP=25;I16=12,12,0,0,858,30884,0,0,1347,78123,0,0,397,8685,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,194:7:0 0,15,148:5:0 +17 3482 . A 0 . DP=25;I16=13,12,0,0,927,35013,0,0,1376,78964,0,0,412,8942,0,0;QS=3,0;MQSB=0.822311;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,202:7:0 0,18,182:6:0 +17 3483 . G 0 . DP=25;I16=12,12,0,0,794,27410,0,0,1316,75364,0,0,412,9002,0,0;QS=3,0;MQSB=0.786628;MQ0F=0 PL:DP:DV 0,33,253:11:0 0,21,183:7:0 0,18,158:6:0 +17 3484 . A C, 0 . DP=24;I16=12,9,0,1,710,25220,14,196,1198,70082,60,3600,346,7514,25,625;QS=2.93665,0.0633484,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.804615;BQB=1;MQ0F=0 PL:DP:DV 0,30,227,30,227,227:10:0 0,7,156,18,159,162:7:1 0,15,133,15,133,133:5:0 +17 3485 . C 0 . DP=23;I16=11,11,0,0,766,27656,0,0,1196,68164,0,0,393,8573,0,0;QS=3,0;MQSB=0.770381;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,163:6:0 0,15,120:5:0 +17 3486 . T 0 . DP=24;I16=12,10,0,0,799,30529,0,0,1196,68164,0,0,398,8756,0,0;QS=3,0;MQSB=0.838545;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,198:7:0 0,15,128:5:0 +17 3487 . C 0 . DP=24;I16=10,11,0,0,724,27586,0,0,1167,67323,0,0,393,8905,0,0;QS=3,0;MQSB=0.914611;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,162:6:0 0,12,92:4:0 +17 3488 . T 0 . DP=24;I16=12,10,0,0,742,27454,0,0,1196,68164,0,0,429,9571,0,0;QS=3,0;MQSB=0.838545;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,172:7:0 0,12,98:4:0 +17 3489 . G 0 . DP=25;I16=13,11,0,0,778,28994,0,0,1285,72605,0,0,433,9675,0,0;QS=3,0;MQSB=0.97965;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,177:8:0 0,12,75:4:0 +17 3490 . T C, 0 . DP=27;I16=14,10,1,0,806,28886,25,625,1254,69846,60,3600,427,9659,12,144;QS=2.90775,0.0922509,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.962269;BQB=1;MQ0F=0 PL:DP:DV 0,39,255,39,255,255:13:0 0,2,168,24,171,183:9:1 0,9,85,9,85,85:3:0 +17 3491 . C 0 . DP=28;I16=15,11,0,0,864,31232,0,0,1405,79805,0,0,445,9903,0,0;QS=3,0;MQSB=0.753395;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,197:9:0 0,9,78:3:0 +17 3492 . T 0 . DP=28;I16=15,11,0,0,852,31516,0,0,1405,79805,0,0,452,9986,0,0;QS=3,0;MQSB=0.753395;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,212:9:0 0,9,96:3:0 +17 3493 . C 0 . DP=28;I16=15,12,0,0,891,32181,0,0,1434,80646,0,0,464,10124,0,0;QS=3,0;MQSB=0.908075;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,27,214:9:0 0,9,80:3:0 +17 3493 . CAAAAAAAAAAAAA CAAAAAAAAAAAA,CAAAAAAAAAAAAAA 0 . INDEL;IDV=2;IMF=0.125;DP=28;I16=9,9,0,2,443,11071,47,1129,1049,62041,89,4441,320,7120,30,650;QS=2.81818,0.0909091,0.0909091;VDB=0.504964;SGB=0.346553;MQSB=0.997118;MQ0F=0 PL:DP:DV 0,19,37,19,40,37:11:2 0,18,39,18,39,39:6:0 0,9,23,9,23,23:3:0 +17 3494 . A 0 . DP=30;I16=15,12,0,0,970,37408,0,0,1465,83405,0,0,440,9568,0,0;QS=3,0;MQSB=0.723173;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,220:9:0 0,12,117:4:0 +17 3495 . A 0 . DP=31;I16=15,13,0,0,966,36178,0,0,1525,87005,0,0,472,10270,0,0;QS=3,0;MQSB=0.695496;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,210:9:0 0,15,129:5:0 +17 3496 . A 0 . DP=31;I16=15,13,0,0,974,36928,0,0,1525,87005,0,0,477,10281,0,0;QS=3,0;MQSB=0.695496;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,207:9:0 0,15,138:5:0 +17 3497 . A 0 . DP=32;I16=14,14,0,0,1015,39525,0,0,1525,87005,0,0,460,9834,0,0;QS=3,0;MQSB=0.62781;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,208:8:0 0,18,148:6:0 +17 3498 . A 0 . DP=32;I16=14,14,0,0,982,37264,0,0,1556,89764,0,0,460,9628,0,0;QS=3,0;MQSB=0.813104;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,27,220:9:0 0,15,115:5:0 +17 3499 . A 0 . DP=32;I16=14,14,0,0,1024,40072,0,0,1525,87005,0,0,489,10267,0,0;QS=3,0;MQSB=0.62781;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,222:8:0 0,18,144:6:0 +17 3500 . A 0 . DP=31;I16=14,14,0,0,995,38097,0,0,1525,87005,0,0,494,10316,0,0;QS=3,0;MQSB=0.62781;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,214:8:0 0,18,150:6:0 +17 3501 . A 0 . DP=31;I16=14,14,0,0,1017,39845,0,0,1525,87005,0,0,499,10399,0,0;QS=3,0;MQSB=0.62781;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,221:8:0 0,18,149:6:0 +17 3502 . A 0 . DP=31;I16=14,14,0,0,1051,41955,0,0,1525,87005,0,0,504,10516,0,0;QS=3,0;MQSB=0.62781;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,223:8:0 0,18,154:6:0 +17 3503 . A 0 . DP=31;I16=14,14,0,0,1038,40832,0,0,1525,87005,0,0,509,10667,0,0;QS=3,0;MQSB=0.62781;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,229:8:0 0,18,155:6:0 +17 3504 . A 0 . DP=31;I16=14,14,0,0,1037,41235,0,0,1525,87005,0,0,512,10750,0,0;QS=3,0;MQSB=0.62781;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,229:8:0 0,18,145:6:0 +17 3505 . A 0 . DP=31;I16=14,14,0,0,1039,40959,0,0,1525,87005,0,0,514,10814,0,0;QS=3,0;MQSB=0.62781;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,24,233:8:0 0,18,156:6:0 +17 3506 . A 0 . DP=32;I16=11,13,0,0,889,34265,0,0,1378,80882,0,0,427,9079,0,0;QS=3,0;MQSB=0.998323;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,201:6:0 0,18,158:6:0 +17 3507 . T 0 . DP=31;I16=10,17,0,0,995,38431,0,0,1527,88923,0,0,493,10499,0,0;QS=3,0;MQSB=0.997168;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,187:6:0 0,18,153:6:0 +17 3508 . C 0 . DP=31;I16=10,17,0,0,997,40091,0,0,1527,88923,0,0,499,10675,0,0;QS=3,0;MQSB=0.997168;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,160:6:0 0,15,119:5:0 +17 3509 . A 0 . DP=30;I16=11,17,0,0,995,37147,0,0,1556,89764,0,0,529,11459,0,0;QS=3,0;MQSB=0.960952;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,175:6:0 0,15,125:5:0 +17 3510 . C A, 0 . DP=29;I16=9,17,1,0,959,37997,40,1600,1498,88082,29,841,483,10351,25,625;QS=2.95246,0.047541,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.997168;BQB=1;MQ0F=0 PL:DP:DV 0,19,255,45,255,255:16:1 0,18,150,18,150,150:6:0 0,15,119,15,119,119:5:0 +17 3511 . A 0 . DP=32;I16=11,17,0,0,923,33125,0,0,1587,92523,0,0,512,11150,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,169:6:0 0,15,115:5:0 +17 3512 . C 0 . DP=32;I16=10,18,0,0,1058,42208,0,0,1618,95282,0,0,493,10733,0,0;QS=3,0;MQSB=0.891417;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,181:6:0 0,15,131:5:0 +17 3513 . C A, 0 . DP=32;I16=10,18,1,0,1074,42406,13,169,1618,95282,29,841,498,10926,25,625;QS=2.98,0.02,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.995968;BQB=1;MQ0F=0 PL:DP:DV 0,39,255,51,255,255:18:1 0,18,190,18,190,190:6:0 0,15,136,15,136,136:5:0 +17 3514 . A 0 . DP=33;I16=11,19,0,0,1101,42213,0,0,1707,99723,0,0,528,11778,0,0;QS=3,0;MQSB=0.997918;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,199:7:0 0,15,132:5:0 +17 3515 . T 0 . DP=33;I16=12,19,0,0,1130,43380,0,0,1736,100564,0,0,557,12563,0,0;QS=3,0;MQSB=0.960505;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,192:7:0 0,15,126:5:0 +17 3516 . T 0 . DP=34;I16=14,17,0,0,1147,44331,0,0,1767,103323,0,0,536,12078,0,0;QS=3,0;MQSB=0.924242;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,203:7:0 0,15,133:5:0 +17 3517 . T 0 . DP=34;I16=14,18,0,0,1183,46549,0,0,1796,104164,0,0,565,12773,0,0;QS=3,0;MQSB=0.988522;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,210:7:0 0,15,153:5:0 +17 3518 . T 0 . DP=34;I16=14,18,0,0,1165,44867,0,0,1796,104164,0,0,568,12826,0,0;QS=3,0;MQSB=0.988522;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,203:7:0 0,15,141:5:0 +17 3519 . G 0 . DP=33;I16=13,18,0,0,1158,46678,0,0,1736,100564,0,0,572,12912,0,0;QS=3,0;MQSB=0.980167;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,18,189:6:0 0,15,154:5:0 +17 3520 . G 0 . DP=33;I16=12,18,0,0,1111,42471,0,0,1707,99723,0,0,552,12438,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,183:6:0 0,15,151:5:0 +17 3521 . C 0 . DP=32;I16=11,17,0,0,1077,43755,0,0,1649,98041,0,0,530,11850,0,0;QS=3,0;MQSB=0.967085;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,185:6:0 0,15,143:5:0 +17 3522 . T 0 . DP=32;I16=12,17,0,0,1125,46329,0,0,1678,98882,0,0,552,12274,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,199:6:0 0,15,158:5:0 +17 3523 . T 0 . DP=31;I16=11,16,0,0,996,38204,0,0,1558,91682,0,0,544,12286,0,0;QS=3,0;MQSB=0.992419;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,193:6:0 0,15,145:5:0 +17 3524 . C 0 . DP=31;I16=11,16,0,0,1067,43883,0,0,1589,94441,0,0,538,11960,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,192:6:0 0,15,152:5:0 +17 3525 . A 0 . DP=31;I16=13,16,0,0,1132,46402,0,0,1678,98882,0,0,556,12250,0,0;QS=3,0;MQSB=0.997839;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,200:6:0 0,15,165:5:0 +17 3526 . G 0 . DP=31;I16=12,16,0,0,1090,43912,0,0,1649,98041,0,0,543,12053,0,0;QS=3,0;MQSB=0.96195;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,181:6:0 0,15,147:5:0 +17 3527 . A 0 . DP=31;I16=13,16,0,0,1068,41740,0,0,1678,98882,0,0,560,12334,0,0;QS=3,0;MQSB=0.997839;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,170:6:0 0,15,157:5:0 +17 3528 . T 0 . DP=31;I16=13,16,0,0,1076,41782,0,0,1678,98882,0,0,561,12369,0,0;QS=3,0;MQSB=0.997839;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,193:6:0 0,15,152:5:0 +17 3529 . T 0 . DP=31;I16=12,16,0,0,1016,38674,0,0,1649,98041,0,0,550,12290,0,0;QS=3,0;MQSB=0.96195;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,184:6:0 0,15,154:5:0 +17 3530 . G 0 . DP=30;I16=12,17,0,0,1070,40570,0,0,1709,101641,0,0,578,13032,0,0;QS=3,0;MQSB=0.965321;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,176:6:0 0,18,175:6:0 +17 3531 . C A, 0 . DP=31;I16=13,17,1,0,1080,40304,38,1444,1738,102482,29,841,607,13801,10,100;QS=2.95773,0.0422741,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.924242;BQB=1;MQ0F=0 PL:DP:DV 0,28,255,54,255,255:19:1 0,18,172,18,172,172:6:0 0,18,175,18,175,175:6:0 +17 3532 . A 0 . DP=31;I16=14,17,0,0,1136,42380,0,0,1767,103323,0,0,619,14003,0,0;QS=3,0;MQSB=0.924242;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,180:6:0 0,18,184:6:0 +17 3533 . T 0 . DP=31;I16=13,17,0,0,1074,39206,0,0,1738,102482,0,0,595,13457,0,0;QS=3,0;MQSB=0.996503;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,180:6:0 0,18,176:6:0 +17 3534 . A 0 . DP=30;I16=12,17,0,0,1014,36168,0,0,1678,98882,0,0,597,13561,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,165:6:0 0,18,175:6:0 +17 3535 . T 0 . DP=31;I16=14,17,0,0,1042,36456,0,0,1767,103323,0,0,624,14314,0,0;QS=3,0;MQSB=0.924242;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,162:6:0 0,18,164:6:0 +17 3536 . C 0 . DP=31;I16=13,17,0,0,1102,41182,0,0,1738,102482,0,0,602,13842,0,0;QS=3,0;MQSB=0.996503;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,178:6:0 0,18,180:6:0 +17 3537 . C 0 . DP=32;I16=13,17,0,0,1142,43828,0,0,1769,105241,0,0,598,13854,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,194:7:0 0,18,185:6:0 +17 3538 . T 0 . DP=32;I16=14,17,0,0,1151,43471,0,0,1798,106082,0,0,603,13923,0,0;QS=3,0;MQSB=0.998229;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,211:7:0 0,18,185:6:0 +17 3539 . C 0 . DP=32;I16=12,17,0,0,1077,40959,0,0,1709,101641,0,0,600,13994,0,0;QS=3,0;MQSB=0.965321;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,170:6:0 0,18,173:6:0 +17 3540 . C 0 . DP=31;I16=13,17,0,0,1134,43546,0,0,1769,105241,0,0,603,14055,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,209:7:0 0,18,172:6:0 +17 3541 . T 0 . DP=32;I16=13,18,0,0,1143,42901,0,0,1829,108841,0,0,604,14134,0,0;QS=3,0;MQSB=0.966712;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,224:8:0 0,18,187:6:0 +17 3542 . G 0 . DP=32;I16=13,18,0,0,1152,43714,0,0,1829,108841,0,0,604,14134,0,0;QS=3,0;MQSB=0.966712;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,223:8:0 0,18,172:6:0 +17 3543 . C 0 . DP=31;I16=13,17,0,0,1142,43818,0,0,1769,105241,0,0,605,14153,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,221:8:0 0,18,188:6:0 +17 3544 . A 0 . DP=31;I16=13,17,0,0,1089,40065,0,0,1769,105241,0,0,606,14190,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,221:8:0 0,18,173:6:0 +17 3545 . A 0 . DP=30;I16=13,16,0,0,1118,43688,0,0,1709,101641,0,0,607,14195,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,228:7:0 0,18,196:6:0 +17 3546 . G 0 . DP=30;I16=14,16,0,0,1131,43425,0,0,1738,102482,0,0,630,14698,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,206:7:0 0,18,179:6:0 +17 3547 . G 0 . DP=31;I16=13,17,0,0,1076,39798,0,0,1769,105241,0,0,607,14163,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,189:7:0 0,18,187:6:0 +17 3548 . A 0 . DP=31;I16=13,17,0,0,1071,39059,0,0,1769,105241,0,0,608,14178,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,208:7:0 0,18,179:6:0 +17 3549 . T 0 . DP=30;I16=13,16,0,0,1008,35928,0,0,1678,98882,0,0,605,13989,0,0;QS=3,0;MQSB=0.997839;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,180:6:0 0,15,152:5:0 +17 3550 . A 0 . DP=30;I16=13,16,0,0,1061,39371,0,0,1709,101641,0,0,612,14270,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,194:7:0 0,15,173:5:0 +17 3551 . T 0 . DP=30;I16=13,16,0,0,1026,36844,0,0,1709,101641,0,0,613,14295,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,192:7:0 0,15,162:5:0 +17 3552 . A 0 . DP=30;I16=14,16,0,0,1080,39588,0,0,1738,102482,0,0,631,14627,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,202:7:0 0,15,158:5:0 +17 3553 . T A, 0 . DP=30;I16=13,16,1,0,1047,38333,20,400,1709,101641,29,841,616,14398,16,256;QS=2.96795,0.0320513,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.999136;BQB=1;MQ0F=0 PL:DP:DV 0,34,255,51,255,255:18:1 0,18,178,18,178,178:6:0 0,18,183,18,183,183:6:0 +17 3554 . A 0 . DP=30;I16=14,16,0,0,1063,38413,0,0,1738,102482,0,0,632,14602,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,185:6:0 0,18,179:6:0 +17 3555 . C 0 . DP=30;I16=14,16,0,0,1021,35781,0,0,1738,102482,0,0,632,14574,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,169:6:0 0,18,163:6:0 +17 3556 . G 0 . DP=30;I16=13,16,0,0,1014,36426,0,0,1709,101641,0,0,618,14350,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,168:6:0 0,18,173:6:0 +17 3557 . C 0 . DP=31;I16=14,16,0,0,1001,34919,0,0,1769,105241,0,0,618,14342,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,140:6:0 0,18,165:6:0 +17 3558 . G 0 . DP=31;I16=15,16,0,0,1036,35974,0,0,1798,106082,0,0,630,14476,0,0;QS=3,0;MQSB=0.999805;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,159:6:0 0,18,171:6:0 +17 3559 . T 0 . DP=30;I16=14,16,0,0,1086,40202,0,0,1769,105241,0,0,619,14341,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,171:6:0 0,18,192:6:0 +17 3560 . G 0 . DP=31;I16=14,16,0,0,1151,45035,0,0,1738,102482,0,0,611,14127,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,165:5:0 0,18,194:6:0 +17 3561 . A 0 . DP=31;I16=15,16,0,0,1147,43431,0,0,1798,106082,0,0,626,14366,0,0;QS=3,0;MQSB=0.999805;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,186:6:0 0,18,196:6:0 +17 3562 . A 0 . DP=31;I16=16,15,0,0,1157,43859,0,0,1798,106082,0,0,623,14257,0,0;QS=3,0;MQSB=0.999805;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,192:6:0 0,21,213:7:0 +17 3563 . A 0 . DP=31;I16=16,15,0,0,1162,44010,0,0,1798,106082,0,0,620,14124,0,0;QS=3,0;MQSB=0.999805;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,192:6:0 0,21,216:7:0 +17 3564 . T 0 . DP=31;I16=15,15,0,0,1132,43298,0,0,1769,105241,0,0,610,13932,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,192:6:0 0,21,214:7:0 +17 3565 . T 0 . DP=32;I16=16,16,0,0,1163,42649,0,0,1858,109682,0,0,611,13791,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,189:6:0 0,21,212:7:0 +17 3566 . C 0 . DP=32;I16=16,16,0,0,1162,43586,0,0,1858,109682,0,0,606,13596,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,181:6:0 0,21,209:7:0 +17 3567 . A 0 . DP=32;I16=15,16,0,0,1181,45245,0,0,1829,108841,0,0,597,13375,0,0;QS=3,0;MQSB=0.957006;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,192:6:0 0,21,222:7:0 +17 3568 . A 0 . DP=32;I16=15,16,0,0,1194,46670,0,0,1829,108841,0,0,592,13200,0,0;QS=3,0;MQSB=0.957006;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,204:6:0 0,21,228:7:0 +17 3569 . G 0 . DP=31;I16=15,16,0,0,1164,44544,0,0,1829,108841,0,0,586,13006,0,0;QS=3,0;MQSB=0.957006;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,180:6:0 0,21,204:7:0 +17 3570 . T 0 . DP=30;I16=14,15,0,0,1029,37527,0,0,1709,101641,0,0,572,12730,0,0;QS=3,0;MQSB=0.954405;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,12,136:4:0 0,21,213:7:0 +17 3571 . C 0 . DP=28;I16=13,15,0,0,1066,41192,0,0,1649,98041,0,0,568,12564,0,0;QS=3,0;MQSB=0.956162;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,138:4:0 0,21,215:7:0 +17 3572 . A 0 . DP=29;I16=13,16,0,0,1108,42566,0,0,1709,101641,0,0,564,12426,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,172:5:0 0,21,218:7:0 +17 3573 . A 0 . DP=29;I16=13,16,0,0,1119,43403,0,0,1709,101641,0,0,558,12168,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,174:5:0 0,21,220:7:0 +17 3574 . T 0 . DP=29;I16=13,16,0,0,1104,42220,0,0,1709,101641,0,0,552,11942,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,175:5:0 0,21,218:7:0 +17 3575 . G 0 . DP=29;I16=13,16,0,0,1122,43748,0,0,1709,101641,0,0,546,11748,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,161:5:0 0,21,212:7:0 +17 3576 . A 0 . DP=29;I16=13,16,0,0,1043,38405,0,0,1709,101641,0,0,540,11586,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,170:5:0 0,21,213:7:0 +17 3577 . C 0 . DP=30;I16=13,17,0,0,1123,42529,0,0,1769,105241,0,0,534,11456,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,161:5:0 0,21,211:7:0 +17 3578 . A 0 . DP=30;I16=13,17,0,0,1148,44236,0,0,1769,105241,0,0,529,11359,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,178:5:0 0,21,216:7:0 +17 3579 . A 0 . DP=29;I16=13,16,0,0,1051,38961,0,0,1709,101641,0,0,524,11244,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,172:5:0 0,18,192:6:0 +17 3580 . A 0 . DP=29;I16=13,16,0,0,1104,42344,0,0,1709,101641,0,0,519,11159,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,172:5:0 0,18,201:6:0 +17 3581 . T 0 . DP=29;I16=13,16,0,0,1088,41226,0,0,1709,101641,0,0,513,11055,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,161:5:0 0,18,199:6:0 +17 3582 . C 0 . DP=29;I16=13,16,0,0,1120,43616,0,0,1709,101641,0,0,506,10934,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,172:5:0 0,18,201:6:0 +17 3583 . A 0 . DP=30;I16=14,16,0,0,1130,43606,0,0,1769,105241,0,0,498,10796,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,183:5:0 0,21,213:7:0 +17 3584 . G 0 . DP=29;I16=12,16,0,0,1027,38895,0,0,1649,98041,0,0,487,10665,0,0;QS=3,0;MQSB=0.96195;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,137:4:0 0,21,209:7:0 +17 3585 . A 0 . DP=31;I16=14,17,0,0,1057,37719,0,0,1829,108841,0,0,486,10616,0,0;QS=3,0;MQSB=0.962133;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,168:5:0 0,24,209:8:0 +17 3586 . A 0 . DP=30;I16=14,15,0,0,1053,40043,0,0,1709,101641,0,0,477,10461,0,0;QS=3,0;MQSB=0.954405;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,174:5:0 0,24,213:8:0 +17 3587 . G A, 0 . DP=29;I16=4,7,10,6,426,16884,555,20381,660,39600,960,57600,192,4420,280,5942;QS=1.32665,1.67335,0;VDB=0.902044;SGB=-3.91326;RPB=0.800999;MQB=1;MQSB=1;BQB=0.156944;MQ0F=0 PL:DP:DV 161,0,184,182,205,255:14:7 22,0,118,34,121,148:5:1 212,24,0,212,24,212:8:8 +17 3588 . A 0 . DP=29;I16=14,14,0,0,999,36973,0,0,1680,100800,0,0,470,10254,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,166:5:0 0,24,215:8:0 +17 3589 . A 0 . DP=28;I16=14,13,0,0,967,35935,0,0,1620,97200,0,0,467,10173,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,166:5:0 0,24,206:8:0 +17 3590 . A 0 . DP=27;I16=13,13,0,0,948,35860,0,0,1560,93600,0,0,464,10072,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,146:4:0 0,24,211:8:0 +17 3591 . A 0 . DP=26;I16=13,13,0,0,913,33539,0,0,1560,93600,0,0,459,9901,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,144:4:0 0,24,212:8:0 +17 3592 . A 0 . DP=26;I16=13,13,0,0,893,32087,0,0,1560,93600,0,0,453,9711,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,143:4:0 0,24,199:8:0 +17 3593 . A 0 . DP=26;I16=13,13,0,0,891,31363,0,0,1560,93600,0,0,447,9553,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,137:4:0 0,24,198:8:0 +17 3594 . C 0 . DP=25;I16=12,12,0,0,910,34868,0,0,1440,86400,0,0,426,9170,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,142:4:0 0,24,216:8:0 +17 3595 . A 0 . DP=24;I16=13,11,0,0,918,35274,0,0,1440,86400,0,0,438,9328,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,143:4:0 0,21,199:7:0 +17 3596 . T 0 . DP=24;I16=13,11,0,0,837,30077,0,0,1440,86400,0,0,434,9258,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,138:4:0 0,21,188:7:0 +17 3597 . A 0 . DP=24;I16=13,11,0,0,893,33549,0,0,1440,86400,0,0,430,9216,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,132:4:0 0,21,204:7:0 +17 3598 . T 0 . DP=23;I16=12,10,0,0,778,28226,0,0,1320,79200,0,0,415,9005,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,140:4:0 0,21,162:7:0 +17 3599 . A 0 . DP=23;I16=13,10,0,0,859,32403,0,0,1380,82800,0,0,425,9105,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,142:4:0 0,21,182:7:0 +17 3600 . T 0 . DP=24;I16=14,10,0,0,872,32086,0,0,1435,85825,0,0,422,9036,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,139:4:0 0,21,183:7:0 +17 3601 . A 0 . DP=24;I16=14,10,0,0,862,31424,0,0,1435,85825,0,0,420,8994,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,132:4:0 0,21,186:7:0 +17 3602 . T 0 . DP=25;I16=15,10,0,0,873,31323,0,0,1495,89425,0,0,418,8980,0,0;QS=3,0;MQSB=0.962269;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,161:5:0 0,21,174:7:0 +17 3603 . A 0 . DP=26;I16=15,11,0,0,907,32447,0,0,1555,93025,0,0,416,8944,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,151:5:0 0,24,216:8:0 +17 3604 . C 0 . DP=27;I16=16,11,0,0,905,31199,0,0,1615,96625,0,0,415,8937,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,147:6:0 0,24,201:8:0 +17 3605 . G 0 . DP=27;I16=15,11,0,0,853,28887,0,0,1555,93025,0,0,393,8477,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,171:6:0 0,21,174:7:0 +17 3606 . C 0 . DP=27;I16=15,12,0,0,982,36756,0,0,1615,96625,0,0,415,8967,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,187:6:0 0,27,231:9:0 +17 3607 . A 0 . DP=26;I16=15,11,0,0,927,33859,0,0,1555,93025,0,0,417,9005,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,183:6:0 0,27,232:9:0 +17 3608 . A 0 . DP=27;I16=14,12,0,0,930,34054,0,0,1555,93025,0,0,394,8450,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,176:6:0 0,24,232:8:0 +17 3609 . A 0 . DP=27;I16=15,12,0,0,955,34701,0,0,1615,96625,0,0,421,9127,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,186:6:0 0,27,238:9:0 +17 3610 . C 0 . DP=27;I16=14,12,0,0,915,33071,0,0,1555,93025,0,0,397,8537,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,172:6:0 0,24,221:8:0 +17 3611 . C 0 . DP=25;I16=13,11,0,0,899,33995,0,0,1435,85825,0,0,398,8502,0,0;QS=3,0;MQSB=0.950498;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,173:6:0 0,24,234:8:0 +17 3612 . A 0 . DP=25;I16=14,11,0,0,957,37723,0,0,1495,89425,0,0,424,9118,0,0;QS=3,0;MQSB=0.955682;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,18,194:6:0 0,27,251:9:0 +17 3613 . G 0 . DP=26;I16=13,12,0,0,902,33110,0,0,1495,89425,0,0,399,8461,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,172:6:0 0,24,223:8:0 +17 3614 . T 0 . DP=26;I16=14,12,0,0,912,33340,0,0,1555,93025,0,0,425,9083,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,156:6:0 0,27,237:9:0 +17 3615 . A 0 . DP=26;I16=15,11,0,0,946,35138,0,0,1555,93025,0,0,427,9109,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,176:6:0 0,27,242:9:0 +17 3616 . T 0 . DP=26;I16=15,11,0,0,965,36541,0,0,1555,93025,0,0,431,9163,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,185:6:0 0,27,238:9:0 +17 3617 . C 0 . DP=25;I16=14,11,0,0,907,33675,0,0,1495,89425,0,0,436,9196,0,0;QS=3,0;MQSB=0.955682;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,176:6:0 0,24,215:8:0 +17 3618 . C 0 . DP=25;I16=14,11,0,0,964,37698,0,0,1495,89425,0,0,441,9259,0,0;QS=3,0;MQSB=0.955682;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,190:6:0 0,24,225:8:0 +17 3619 . T 0 . DP=25;I16=14,11,0,0,961,37553,0,0,1495,89425,0,0,446,9352,0,0;QS=3,0;MQSB=0.955682;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,194:6:0 0,24,238:8:0 +17 3620 . A 0 . DP=25;I16=14,11,0,0,880,31656,0,0,1495,89425,0,0,451,9475,0,0;QS=3,0;MQSB=0.955682;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,178:6:0 0,24,212:8:0 +17 3621 . C 0 . DP=25;I16=14,11,0,0,949,36561,0,0,1495,89425,0,0,456,9628,0,0;QS=3,0;MQSB=0.955682;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,18,182:6:0 0,24,230:8:0 +17 3622 . T 0 . DP=26;I16=15,11,0,0,983,38067,0,0,1555,93025,0,0,460,9762,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,194:7:0 0,24,242:8:0 +17 3623 . G 0 . DP=27;I16=16,11,0,0,969,35645,0,0,1615,96625,0,0,465,9929,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,195:7:0 0,24,209:8:0 +17 3624 . T 0 . DP=27;I16=15,11,0,0,948,35330,0,0,1555,93025,0,0,448,9596,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,188:6:0 0,24,224:8:0 +17 3625 . G 0 . DP=27;I16=14,12,0,0,983,37483,0,0,1555,93025,0,0,453,9735,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,210:7:0 0,24,219:8:0 +17 3626 . T 0 . DP=28;I16=15,12,0,0,998,37364,0,0,1615,96625,0,0,458,9854,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,214:7:0 0,27,229:9:0 +17 3627 . G 0 . DP=29;I16=15,13,0,0,999,36375,0,0,1675,100225,0,0,464,10004,0,0;QS=3,0;MQSB=0.956162;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,199:7:0 0,27,224:9:0 +17 3628 . T 0 . DP=29;I16=15,13,0,0,1033,38721,0,0,1675,100225,0,0,471,10187,0,0;QS=3,0;MQSB=0.956162;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,206:7:0 0,27,232:9:0 +17 3629 . G 0 . DP=29;I16=15,13,0,0,1058,40226,0,0,1675,100225,0,0,476,10304,0,0;QS=3,0;MQSB=0.956162;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,207:7:0 0,27,235:9:0 +17 3630 . T 0 . DP=30;I16=15,14,0,0,1052,39072,0,0,1735,103825,0,0,480,10404,0,0;QS=3,0;MQSB=0.954405;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,216:7:0 0,27,223:9:0 +17 3631 . C 0 . DP=29;I16=13,14,0,0,884,29476,0,0,1615,96625,0,0,461,9911,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,186:7:0 0,21,179:7:0 +17 3632 . G 0 . DP=29;I16=14,14,0,0,914,31068,0,0,1675,100225,0,0,491,10649,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,183:7:0 0,24,181:8:0 +17 3633 . T 0 . DP=29;I16=14,14,0,0,1022,38214,0,0,1675,100225,0,0,496,10792,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,216:7:0 0,24,222:8:0 +17 3634 . T 0 . DP=29;I16=14,14,0,0,1043,39891,0,0,1675,100225,0,0,500,10914,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,219:7:0 0,24,227:8:0 +17 3635 . T 0 . DP=28;I16=13,14,0,0,1029,39507,0,0,1615,96625,0,0,505,11063,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,219:7:0 0,24,224:8:0 +17 3636 . G 0 . DP=28;I16=13,14,0,0,1001,37681,0,0,1615,96625,0,0,510,11238,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,201:7:0 0,24,217:8:0 +17 3637 . T 0 . DP=27;I16=13,14,0,0,1019,39331,0,0,1615,96625,0,0,515,11439,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,212:7:0 0,24,240:8:0 +17 3638 . T 0 . DP=26;I16=12,14,0,0,967,36467,0,0,1555,93025,0,0,520,11616,0,0;QS=3,0;MQSB=0.937241;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,185:6:0 0,24,222:8:0 +17 3639 . G 0 . DP=27;I16=13,14,0,0,997,37265,0,0,1615,96625,0,0,524,11768,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,183:6:0 0,27,221:9:0 +17 3640 . T 0 . DP=27;I16=13,14,0,0,1001,37533,0,0,1615,96625,0,0,527,11847,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,191:6:0 0,27,229:9:0 +17 3641 . G 0 . DP=27;I16=13,14,0,0,977,36379,0,0,1615,96625,0,0,529,11905,0,0;QS=3,0;MQSB=0.94394;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,178:6:0 0,27,224:9:0 +17 3642 . T 0 . DP=26;I16=12,13,0,0,931,35169,0,0,1495,89425,0,0,506,11314,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,169:5:0 0,24,225:8:0 +17 3643 . T 0 . DP=26;I16=13,13,0,0,968,36820,0,0,1555,93025,0,0,533,11997,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,176:5:0 0,27,230:9:0 +17 3644 . T 0 . DP=26;I16=12,13,0,0,961,37477,0,0,1495,89425,0,0,517,11755,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,175:5:0 0,24,236:8:0 +17 3645 . T 0 . DP=26;I16=13,13,0,0,980,37508,0,0,1555,93025,0,0,537,12185,0,0;QS=3,0;MQSB=0.945959;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,175:5:0 0,27,239:9:0 +17 3646 . C 0 . DP=26;I16=12,13,0,0,766,25026,0,0,1495,89425,0,0,514,11690,0,0;QS=3,0;MQSB=0.939413;MQ0F=0 PL:DP:DV 0,33,234:11:0 0,15,136:5:0 0,27,188:9:0 +17 3647 . G 0 . DP=26;I16=12,12,0,0,820,29600,0,0,1435,85825,0,0,492,11218,0,0;QS=3,0;MQSB=0.941765;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,151:5:0 0,21,173:7:0 +17 3648 . A 0 . DP=26;I16=13,12,0,0,924,34680,0,0,1495,89425,0,0,519,11919,0,0;QS=3,0;MQSB=0.948139;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,174:5:0 0,24,225:8:0 +17 3649 . C 0 . DP=26;I16=14,12,0,0,955,36105,0,0,1555,93025,0,0,545,12593,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,173:5:0 0,27,226:9:0 +17 3650 . A 0 . DP=27;I16=15,12,0,0,1033,40511,0,0,1615,96625,0,0,546,12664,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,196:6:0 0,27,246:9:0 +17 3651 . G 0 . DP=27;I16=15,12,0,0,1035,40351,0,0,1615,96625,0,0,547,12707,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,194:6:0 0,27,233:9:0 +17 3652 . C 0 . DP=29;I16=15,13,0,0,1010,38264,0,0,1675,100225,0,0,521,12047,0,0;QS=3,0;MQSB=0.956162;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,198:6:0 0,27,225:9:0 +17 3653 . T 0 . DP=29;I16=16,13,0,0,1109,42919,0,0,1735,103825,0,0,546,12610,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,202:6:0 0,27,239:9:0 +17 3654 . G 0 . DP=28;I16=14,12,0,0,981,37447,0,0,1555,93025,0,0,514,11882,0,0;QS=3,0;MQSB=0.953497;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,184:6:0 0,18,180:6:0 +17 3655 . T 0 . DP=28;I16=16,12,0,0,999,37029,0,0,1675,100225,0,0,541,12505,0,0;QS=3,0;MQSB=0.96195;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,190:6:0 0,21,179:7:0 +17 3656 . C 0 . DP=28;I16=15,12,0,0,963,35883,0,0,1615,96625,0,0,518,11848,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,164:5:0 0,21,191:7:0 +17 3657 . C 0 . DP=28;I16=15,12,0,0,923,32223,0,0,1615,96625,0,0,520,11836,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,154:5:0 0,21,192:7:0 +17 3658 . G 0 . DP=28;I16=15,12,0,0,876,29960,0,0,1615,96625,0,0,539,12405,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,142:5:0 0,21,163:7:0 +17 3659 . T 0 . DP=28;I16=16,12,0,0,996,36682,0,0,1675,100225,0,0,548,12448,0,0;QS=3,0;MQSB=0.96195;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,163:6:0 0,21,186:7:0 +17 3660 . G 0 . DP=28;I16=15,12,0,0,997,37571,0,0,1615,96625,0,0,526,11920,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,172:6:0 0,18,171:6:0 +17 3661 . T 0 . DP=28;I16=16,12,0,0,1013,37837,0,0,1675,100225,0,0,549,12423,0,0;QS=3,0;MQSB=0.96195;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,180:6:0 0,21,188:7:0 +17 3662 . T 0 . DP=28;I16=15,12,0,0,987,36627,0,0,1615,96625,0,0,528,11980,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,182:6:0 0,18,184:6:0 +17 3663 . A 0 . DP=29;I16=16,12,0,0,997,36233,0,0,1675,100225,0,0,527,11959,0,0;QS=3,0;MQSB=0.96195;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,170:6:0 0,18,180:6:0 +17 3664 . T 0 . DP=29;I16=17,12,0,0,1044,38402,0,0,1735,103825,0,0,550,12490,0,0;QS=3,0;MQSB=0.965321;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,183:6:0 0,21,196:7:0 +17 3665 . A 0 . DP=27;I16=16,11,0,0,1017,38535,0,0,1615,96625,0,0,552,12510,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,182:6:0 0,21,208:7:0 +17 3666 . A 0 . DP=27;I16=16,11,0,0,1036,40292,0,0,1615,96625,0,0,554,12550,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,193:6:0 0,21,208:7:0 +17 3667 . T 0 . DP=27;I16=15,11,0,0,955,35895,0,0,1555,93025,0,0,540,12354,0,0;QS=3,0;MQSB=0.960078;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,189:6:0 0,18,189:6:0 +17 3668 . A 0 . DP=27;I16=16,11,0,0,981,36297,0,0,1615,96625,0,0,557,12641,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,182:6:0 0,21,209:7:0 +17 3669 . A 0 . DP=27;I16=16,11,0,0,1030,39666,0,0,1615,96625,0,0,558,12694,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,194:6:0 0,21,209:7:0 +17 3670 . T 0 . DP=28;I16=17,11,0,0,1057,40245,0,0,1675,100225,0,0,559,12769,0,0;QS=3,0;MQSB=0.967085;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,181:6:0 0,24,220:8:0 +17 3671 . T 0 . DP=28;I16=17,11,0,0,1059,40427,0,0,1675,100225,0,0,561,12867,0,0;QS=3,0;MQSB=0.967085;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,193:6:0 0,24,223:8:0 +17 3672 . C 0 . DP=28;I16=16,11,0,0,988,37264,0,0,1615,96625,0,0,550,12820,0,0;QS=3,0;MQSB=0.96384;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,169:6:0 0,21,205:7:0 +17 3673 . C 0 . DP=27;I16=16,10,0,0,1016,40148,0,0,1555,93025,0,0,528,12314,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,154:5:0 0,24,219:8:0 +17 3674 . T 0 . DP=27;I16=17,10,0,0,1035,40645,0,0,1615,96625,0,0,556,13028,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,155:5:0 0,24,228:8:0 +17 3675 . C 0 . DP=27;I16=17,10,0,0,1049,41413,0,0,1615,96625,0,0,558,13090,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,149:5:0 0,24,222:8:0 +17 3676 . T 0 . DP=27;I16=17,10,0,0,1040,40640,0,0,1615,96625,0,0,559,13125,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,159:5:0 0,24,231:8:0 +17 3677 . A 0 . DP=27;I16=16,10,0,0,922,34182,0,0,1555,93025,0,0,537,12557,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,136:5:0 0,24,217:8:0 +17 3678 . G 0 . DP=27;I16=17,10,0,0,1009,38307,0,0,1615,96625,0,0,563,13159,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,149:5:0 0,24,216:8:0 +17 3679 . T 0 . DP=27;I16=17,10,0,0,1018,39274,0,0,1615,96625,0,0,563,13105,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,156:5:0 0,24,227:8:0 +17 3680 . T 0 . DP=27;I16=17,10,0,0,988,36872,0,0,1615,96625,0,0,562,13022,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,157:5:0 0,24,202:8:0 +17 3681 . C 0 . DP=27;I16=17,10,0,0,1012,39154,0,0,1615,96625,0,0,560,12910,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,157:5:0 0,24,217:8:0 +17 3682 . A 0 . DP=27;I16=17,10,0,0,1009,38221,0,0,1615,96625,0,0,557,12769,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,156:5:0 0,24,220:8:0 +17 3683 . A 0 . DP=27;I16=17,9,0,0,966,36748,0,0,1555,93025,0,0,546,12552,0,0;QS=3,0;MQSB=0.971017;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,153:5:0 0,24,225:8:0 +17 3684 . A 0 . DP=26;I16=16,10,0,0,974,37440,0,0,1555,93025,0,0,550,12456,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,155:5:0 0,21,215:7:0 +17 3685 . T 0 . DP=26;I16=16,10,0,0,954,36330,0,0,1555,93025,0,0,547,12333,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,148:5:0 0,21,207:7:0 +17 3686 . T 0 . DP=26;I16=16,10,0,0,979,37645,0,0,1555,93025,0,0,544,12232,0,0;QS=3,0;MQSB=0.965874;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,162:5:0 0,21,216:7:0 +17 3687 . T 0 . DP=27;I16=16,11,0,0,1028,39276,0,0,1592,94394,0,0,541,12153,0,0;QS=3,0;MQSB=0.989102;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,159:5:0 0,24,229:8:0 +17 3688 . A 0 . DP=28;I16=17,10,0,0,1007,37883,0,0,1569,92163,0,0,526,11904,0,0;QS=3,0;MQSB=0.99874;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,148:5:0 0,24,232:8:0 +17 3689 . T 0 . DP=28;I16=17,11,0,0,1042,39780,0,0,1629,95763,0,0,535,11919,0,0;QS=3,0;MQSB=0.995584;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,162:5:0 0,24,233:8:0 +17 3690 . T 0 . DP=28;I16=17,11,0,0,1051,39981,0,0,1629,95763,0,0,532,11816,0,0;QS=3,0;MQSB=0.995584;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,160:5:0 0,24,225:8:0 +17 3691 . C 0 . DP=28;I16=16,11,0,0,1037,40549,0,0,1569,92163,0,0,520,11592,0,0;QS=3,0;MQSB=0.992419;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,155:5:0 0,21,214:7:0 +17 3692 . A 0 . DP=29;I16=18,11,0,0,1028,37574,0,0,1689,99363,0,0,522,11496,0,0;QS=3,0;MQSB=0.99773;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,156:5:0 0,24,209:8:0 +17 3693 . T 0 . DP=28;I16=18,10,0,0,1067,40901,0,0,1629,95763,0,0,519,11381,0,0;QS=3,0;MQSB=0.999713;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,160:5:0 0,24,230:8:0 +17 3694 . T 0 . DP=28;I16=18,10,0,0,1043,39659,0,0,1629,95763,0,0,516,11296,0,0;QS=3,0;MQSB=0.999713;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,159:5:0 0,24,234:8:0 +17 3695 . T 0 . DP=28;I16=18,10,0,0,1046,39662,0,0,1629,95763,0,0,513,11241,0,0;QS=3,0;MQSB=0.999713;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,156:5:0 0,24,233:8:0 +17 3696 . T 0 . DP=28;I16=18,10,0,0,1075,41567,0,0,1629,95763,0,0,509,11165,0,0;QS=3,0;MQSB=0.999713;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,162:5:0 0,24,235:8:0 +17 3697 . T 0 . DP=28;I16=18,10,0,0,1031,38399,0,0,1629,95763,0,0,505,11117,0,0;QS=3,0;MQSB=0.999713;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,155:5:0 0,24,229:8:0 +17 3698 . A 0 . DP=28;I16=18,9,0,0,983,36457,0,0,1569,92163,0,0,477,10515,0,0;QS=3,0;MQSB=0.999669;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,144:5:0 0,24,229:8:0 +17 3699 . A 0 . DP=27;I16=17,10,0,0,1011,38455,0,0,1569,92163,0,0,493,10861,0,0;QS=3,0;MQSB=0.99874;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,150:5:0 0,21,226:7:0 +17 3700 . C 0 . DP=28;I16=16,11,0,0,970,35910,0,0,1574,92738,0,0,473,10525,0,0;QS=3,0;MQSB=0.992419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,168:6:0 0,24,212:8:0 +17 3701 . T 0 . DP=28;I16=17,11,0,0,1071,41669,0,0,1634,96338,0,0,484,10618,0,0;QS=3,0;MQSB=0.990092;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,196:6:0 0,24,233:8:0 +17 3702 . T 0 . DP=28;I16=17,10,0,0,1019,38653,0,0,1597,94969,0,0,462,10144,0,0;QS=3,0;MQSB=0.968979;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,184:6:0 0,21,207:7:0 +17 3703 . C 0 . DP=28;I16=17,11,0,0,1059,40561,0,0,1634,96338,0,0,470,10154,0,0;QS=3,0;MQSB=0.990092;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,183:6:0 0,24,232:8:0 +17 3704 . A 0 . DP=28;I16=17,10,0,0,1015,38483,0,0,1574,92738,0,0,439,9347,0,0;QS=3,0;MQSB=0.984677;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,182:6:0 0,21,211:7:0 +17 3705 . T 0 . DP=27;I16=17,10,0,0,992,37112,0,0,1574,92738,0,0,459,9773,0,0;QS=3,0;MQSB=0.984677;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,180:6:0 0,21,209:7:0 +17 3706 . A 0 . DP=27;I16=17,10,0,0,1040,40262,0,0,1574,92738,0,0,454,9608,0,0;QS=3,0;MQSB=0.984677;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,186:6:0 0,21,204:7:0 +17 3707 . G 0 . DP=26;I16=17,9,0,0,974,37394,0,0,1514,89138,0,0,450,9476,0,0;QS=3,0;MQSB=0.977029;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,173:6:0 0,18,168:6:0 +17 3708 . T 0 . DP=26;I16=18,7,0,0,911,33609,0,0,1454,85538,0,0,426,8934,0,0;QS=3,0;MQSB=0.914166;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,182:6:0 0,15,139:5:0 +17 3709 . A 0 . DP=26;I16=18,8,0,0,905,32473,0,0,1491,86907,0,0,445,9305,0,0;QS=3,0;MQSB=0.998458;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,168:6:0 0,18,162:6:0 +17 3710 . C 0 . DP=26;I16=18,8,0,0,924,33504,0,0,1491,86907,0,0,443,9267,0,0;QS=3,0;MQSB=0.998458;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,165:6:0 0,18,159:6:0 +17 3711 . C 0 . DP=26;I16=18,8,0,0,953,35965,0,0,1491,86907,0,0,441,9261,0,0;QS=3,0;MQSB=0.998458;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,164:6:0 0,18,173:6:0 +17 3712 . A 0 . DP=26;I16=18,8,0,0,893,31917,0,0,1491,86907,0,0,439,9287,0,0;QS=3,0;MQSB=0.998458;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,144:6:0 0,18,165:6:0 +17 3713 . C 0 . DP=26;I16=19,7,0,0,908,32834,0,0,1491,86907,0,0,437,9293,0,0;QS=3,0;MQSB=0.989612;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,163:6:0 0,18,164:6:0 +17 3714 . A 0 . DP=27;I16=19,6,0,0,920,34366,0,0,1408,81076,0,0,409,8651,0,0;QS=3,0;MQSB=0.999494;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,177:6:0 0,18,174:6:0 +17 3715 . T 0 . DP=28;I16=21,6,0,0,982,36286,0,0,1505,86045,0,0,408,8616,0,0;QS=3,0;MQSB=0.996181;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,180:6:0 0,18,164:6:0 +17 3716 . T 0 . DP=26;I16=19,7,0,0,927,33833,0,0,1445,82445,0,0,434,9236,0,0;QS=3,0;MQSB=0.966731;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,165:5:0 0,18,164:6:0 +17 3717 . C 0 . DP=26;I16=19,7,0,0,979,37527,0,0,1445,82445,0,0,435,9261,0,0;QS=3,0;MQSB=0.966731;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,165:5:0 0,18,168:6:0 +17 3718 . T 0 . DP=26;I16=19,7,0,0,994,39040,0,0,1445,82445,0,0,435,9265,0,0;QS=3,0;MQSB=0.966731;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,169:5:0 0,18,165:6:0 +17 3719 . A 0 . DP=26;I16=19,6,0,0,889,32163,0,0,1408,81076,0,0,410,8672,0,0;QS=3,0;MQSB=0.747144;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,148:5:0 0,15,142:5:0 +17 3720 . C 0 . DP=26;I16=19,7,0,0,934,34326,0,0,1445,82445,0,0,435,9357,0,0;QS=3,0;MQSB=0.966731;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,148:5:0 0,18,158:6:0 +17 3721 . A 0 . DP=27;I16=20,5,0,0,910,33944,0,0,1405,80725,0,0,385,8195,0,0;QS=3,0;MQSB=0.697274;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,153:5:0 0,15,145:5:0 +17 3722 . C 0 . DP=27;I16=20,7,0,0,964,35276,0,0,1502,85694,0,0,436,9562,0,0;QS=3,0;MQSB=0.927743;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,151:5:0 0,18,165:6:0 +17 3723 . A 0 . DP=25;I16=18,6,0,0,888,33516,0,0,1345,77125,0,0,414,9082,0,0;QS=3,0;MQSB=0.606531;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,134:4:0 0,15,145:5:0 +17 3724 . C 0 . DP=25;I16=18,7,0,0,944,35956,0,0,1382,78494,0,0,442,9878,0,0;QS=3,0;MQSB=0.889393;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,137:4:0 0,18,169:6:0 +17 3725 . T 0 . DP=25;I16=18,7,0,0,973,38263,0,0,1382,78494,0,0,445,10075,0,0;QS=3,0;MQSB=0.889393;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,138:4:0 0,18,190:6:0 +17 3726 . G 0 . DP=24;I16=18,6,0,0,865,32339,0,0,1322,74894,0,0,446,10146,0,0;QS=3,0;MQSB=0.934987;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,93:3:0 0,18,166:6:0 +17 3727 . C 0 . DP=22;I16=17,5,0,0,762,27812,0,0,1202,67694,0,0,447,10139,0,0;QS=3,0;MQSB=0.963102;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,82:3:0 0,15,143:5:0 +17 3728 . C 0 . DP=22;I16=17,5,0,0,792,29850,0,0,1202,67694,0,0,448,10154,0,0;QS=3,0;MQSB=0.963102;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,89:3:0 0,15,160:5:0 +17 3729 . C 0 . DP=22;I16=17,5,0,0,838,32312,0,0,1202,67694,0,0,449,10191,0,0;QS=3,0;MQSB=0.963102;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,93:3:0 0,15,164:5:0 +17 3730 . A 0 . DP=21;I16=17,4,0,0,749,27561,0,0,1142,64094,0,0,448,10100,0,0;QS=3,0;MQSB=0.995997;MQ0F=0 PL:DP:DV 0,39,241:13:0 0,9,98:3:0 0,15,159:5:0 +17 3731 . T 0 . DP=22;I16=18,4,0,0,787,29489,0,0,1152,64194,0,0,447,10031,0,0;QS=3,0;MQSB=0.967917;MQ0F=0 PL:DP:DV 0,42,253:14:0 0,9,101:3:0 0,15,139:5:0 +17 3732 . G 0 . DP=22;I16=18,4,0,0,811,30695,0,0,1152,64194,0,0,447,9985,0,0;QS=3,0;MQSB=0.967917;MQ0F=0 PL:DP:DV 0,42,252:14:0 0,9,101:3:0 0,15,149:5:0 +17 3733 . T 0 . DP=23;I16=19,4,0,0,820,29616,0,0,1212,67794,0,0,447,9963,0,0;QS=3,0;MQSB=0.979651;MQ0F=0 PL:DP:DV 0,45,248:15:0 0,9,101:3:0 0,15,152:5:0 +17 3734 . C 0 . DP=24;I16=20,4,0,0,863,32277,0,0,1272,71394,0,0,447,9915,0,0;QS=3,0;MQSB=0.988072;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,86:3:0 0,15,152:5:0 +17 3735 . C 0 . DP=24;I16=20,4,0,0,826,30112,0,0,1272,71394,0,0,448,9892,0,0;QS=3,0;MQSB=0.988072;MQ0F=0 PL:DP:DV 0,48,254:16:0 0,9,83:3:0 0,15,152:5:0 +17 3736 . C 0 . DP=25;I16=20,3,0,0,839,31471,0,0,1262,71294,0,0,419,9245,0,0;QS=3,0;MQSB=0.963194;MQ0F=0 PL:DP:DV 0,42,235:14:0 0,9,99:3:0 0,18,156:6:0 +17 3737 . C 0 . DP=25;I16=21,4,0,0,894,33402,0,0,1332,74994,0,0,451,9925,0,0;QS=3,0;MQSB=0.993838;MQ0F=0 PL:DP:DV 0,48,251:16:0 0,9,95:3:0 0,18,175:6:0 +17 3738 . T 0 . DP=25;I16=21,4,0,0,926,35484,0,0,1332,74994,0,0,452,9934,0,0;QS=3,0;MQSB=0.993838;MQ0F=0 PL:DP:DV 0,48,253:16:0 0,9,101:3:0 0,18,189:6:0 +17 3739 . C 0 . DP=25;I16=21,4,0,0,958,37390,0,0,1332,74994,0,0,452,9922,0,0;QS=3,0;MQSB=0.993838;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,105:3:0 0,18,181:6:0 +17 3740 . A 0 . DP=24;I16=20,4,0,0,848,31126,0,0,1272,71394,0,0,452,9886,0,0;QS=3,0;MQSB=0.988072;MQ0F=0 PL:DP:DV 0,48,247:16:0 0,9,109:3:0 0,15,163:5:0 +17 3741 . A 0 . DP=24;I16=19,4,0,0,814,30176,0,0,1212,67794,0,0,442,9742,0,0;QS=3,0;MQSB=0.979651;MQ0F=0 PL:DP:DV 0,48,238:16:0 0,6,82:2:0 0,15,172:5:0 +17 3742 . G 0 . DP=24;I16=20,4,0,0,893,34371,0,0,1272,71394,0,0,450,9782,0,0;QS=3,0;MQSB=0.988072;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,101:3:0 0,15,162:5:0 +17 3743 . C 0 . DP=24;I16=19,4,0,0,839,31673,0,0,1262,71294,0,0,437,9619,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,254:15:0 0,9,103:3:0 0,15,158:5:0 +17 3744 . T 0 . DP=24;I16=20,4,0,0,918,36126,0,0,1272,71394,0,0,448,9766,0,0;QS=3,0;MQSB=0.988072;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,118:3:0 0,15,164:5:0 +17 3745 . T 0 . DP=24;I16=19,4,0,0,808,29490,0,0,1212,67794,0,0,422,9166,0,0;QS=3,0;MQSB=0.979651;MQ0F=0 PL:DP:DV 0,45,233:15:0 0,9,108:3:0 0,15,158:5:0 +17 3746 . C 0 . DP=24;I16=20,4,0,0,886,33564,0,0,1272,71394,0,0,445,9789,0,0;QS=3,0;MQSB=0.988072;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,101:3:0 0,15,165:5:0 +17 3747 . C 0 . DP=24;I16=19,4,0,0,833,31071,0,0,1262,71294,0,0,426,9504,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,249:15:0 0,9,103:3:0 0,15,162:5:0 +17 3748 . C 0 . DP=24;I16=19,4,0,0,845,31753,0,0,1262,71294,0,0,422,9464,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,106:3:0 0,15,161:5:0 +17 3749 . C 0 . DP=24;I16=19,4,0,0,844,31888,0,0,1262,71294,0,0,417,9395,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,250:15:0 0,9,111:3:0 0,15,154:5:0 +17 3750 . T 0 . DP=25;I16=21,4,0,0,876,32880,0,0,1309,72763,0,0,431,9709,0,0;QS=3,0;MQSB=0.966906;MQ0F=0 PL:DP:DV 0,51,251:17:0 0,9,112:3:0 0,15,146:5:0 +17 3751 . G 0 . DP=24;I16=19,4,0,0,836,31374,0,0,1239,69063,0,0,408,9274,0,0;QS=3,0;MQSB=0.986928;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,82:2:0 0,15,162:5:0 +17 3752 . G 0 . DP=22;I16=19,2,0,0,728,26270,0,0,1069,58363,0,0,404,9134,0,0;QS=3,0;MQSB=0.868421;MQ0F=0 PL:DP:DV 0,42,182:14:0 0,6,74:2:0 0,15,159:5:0 +17 3753 . C 0 . DP=22;I16=19,3,0,0,761,28017,0,0,1129,61963,0,0,426,9674,0,0;QS=3,0;MQSB=0.995434;MQ0F=0 PL:DP:DV 0,45,213:15:0 0,6,61:2:0 0,15,163:5:0 +17 3754 . T 0 . DP=23;I16=19,3,0,0,767,28751,0,0,1129,61963,0,0,425,9707,0,0;QS=3,0;MQSB=0.995434;MQ0F=0 PL:DP:DV 0,45,218:15:0 0,6,69:2:0 0,15,157:5:0 +17 3755 . C 0 . DP=21;I16=16,4,0,0,749,28747,0,0,1028,55504,0,0,404,9188,0,0;QS=3,0;MQSB=0.777932;MQ0F=0 PL:DP:DV 0,36,219:12:0 0,9,93:3:0 0,15,161:5:0 +17 3756 . C 0 . DP=22;I16=17,4,0,0,782,29994,0,0,1038,55604,0,0,430,9840,0,0;QS=3,0;MQSB=0.885747;MQ0F=0 PL:DP:DV 0,39,229:13:0 0,9,93:3:0 0,15,159:5:0 +17 3757 . T 0 . DP=23;I16=17,6,0,0,828,30942,0,0,1158,62804,0,0,456,10510,0,0;QS=3,0;MQSB=0.9945;MQ0F=0 PL:DP:DV 0,39,210:13:0 0,15,143:5:0 0,15,169:5:0 +17 3758 . G 0 . DP=23;I16=17,6,0,0,832,30792,0,0,1158,62804,0,0,458,10574,0,0;QS=3,0;MQSB=0.9945;MQ0F=0 PL:DP:DV 0,39,220:13:0 0,15,135:5:0 0,15,147:5:0 +17 3759 . C 0 . DP=23;I16=17,4,0,0,756,28338,0,0,1061,57835,0,0,409,9357,0,0;QS=3,0;MQSB=0.964547;MQ0F=0 PL:DP:DV 0,39,220:13:0 0,12,112:4:0 0,12,127:4:0 +17 3760 . A 0 . DP=24;I16=17,7,0,0,792,27956,0,0,1218,66404,0,0,459,10607,0,0;QS=3,0;MQSB=0.95083;MQ0F=0 PL:DP:DV 0,39,203:13:0 0,15,127:5:0 0,18,180:6:0 +17 3761 . A 0 . DP=24;I16=17,7,0,0,871,32185,0,0,1218,66404,0,0,460,10624,0,0;QS=3,0;MQSB=0.95083;MQ0F=0 PL:DP:DV 0,39,215:13:0 0,15,136:5:0 0,18,188:6:0 +17 3762 . C 0 . DP=25;I16=17,7,0,0,831,29665,0,0,1241,68635,0,0,435,9983,0,0;QS=3,0;MQSB=0.69242;MQ0F=0 PL:DP:DV 0,39,209:13:0 0,18,149:6:0 0,15,159:5:0 +17 3763 . C 0 . DP=24;I16=16,8,0,0,837,30619,0,0,1218,66404,0,0,460,10510,0,0;QS=3,0;MQSB=0.844324;MQ0F=0 PL:DP:DV 0,36,213:12:0 0,18,149:6:0 0,18,186:6:0 +17 3764 . A 0 . DP=25;I16=17,7,0,0,856,31506,0,0,1241,68635,0,0,437,9903,0,0;QS=3,0;MQSB=0.69242;MQ0F=0 PL:DP:DV 0,39,212:13:0 0,18,139:6:0 0,15,167:5:0 +17 3765 . C 0 . DP=25;I16=17,7,0,0,845,31099,0,0,1218,66404,0,0,436,9750,0,0;QS=3,0;MQSB=0.95083;MQ0F=0 PL:DP:DV 0,39,200:13:0 0,15,129:5:0 0,18,189:6:0 +17 3766 . A 0 . DP=26;I16=17,9,0,0,953,35331,0,0,1338,73604,0,0,462,10340,0,0;QS=3,0;MQSB=0.811273;MQ0F=0 PL:DP:DV 0,42,248:14:0 0,18,158:6:0 0,18,191:6:0 +17 3767 . A 0 . DP=26;I16=17,9,0,0,924,33656,0,0,1338,73604,0,0,464,10328,0,0;QS=3,0;MQSB=0.811273;MQ0F=0 PL:DP:DV 0,42,246:14:0 0,18,148:6:0 0,18,191:6:0 +17 3768 . A 0 . DP=26;I16=17,9,0,0,922,33842,0,0,1338,73604,0,0,466,10340,0,0;QS=3,0;MQSB=0.811273;MQ0F=0 PL:DP:DV 0,42,237:14:0 0,18,146:6:0 0,18,195:6:0 +17 3769 . T 0 . DP=26;I16=17,8,0,0,891,32735,0,0,1278,70004,0,0,461,10327,0,0;QS=3,0;MQSB=0.884621;MQ0F=0 PL:DP:DV 0,42,246:14:0 0,15,144:5:0 0,18,191:6:0 +17 3770 . C 0 . DP=26;I16=17,9,0,0,923,34049,0,0,1338,73604,0,0,470,10436,0,0;QS=3,0;MQSB=0.811273;MQ0F=0 PL:DP:DV 0,42,252:14:0 0,18,142:6:0 0,18,180:6:0 +17 3771 . T 0 . DP=25;I16=16,8,0,0,852,31694,0,0,1218,66404,0,0,464,10438,0,0;QS=3,0;MQSB=0.844324;MQ0F=0 PL:DP:DV 0,42,253:14:0 0,15,140:5:0 0,15,157:5:0 +17 3772 . A 0 . DP=26;I16=16,10,0,0,836,28434,0,0,1338,73604,0,0,476,10624,0,0;QS=3,0;MQSB=0.685145;MQ0F=0 PL:DP:DV 0,42,236:14:0 0,18,122:6:0 0,18,160:6:0 +17 3773 . C 0 . DP=26;I16=16,10,0,0,893,31801,0,0,1338,73604,0,0,480,10752,0,0;QS=3,0;MQSB=0.685145;MQ0F=0 PL:DP:DV 0,42,253:14:0 0,18,140:6:0 0,18,171:6:0 +17 3774 . T 0 . DP=25;I16=15,10,0,0,895,33455,0,0,1278,70004,0,0,485,10903,0,0;QS=3,0;MQSB=0.624282;MQ0F=0 PL:DP:DV 0,42,253:14:0 0,18,129:6:0 0,15,178:5:0 +17 3775 . C 0 . DP=25;I16=15,9,0,0,855,31825,0,0,1241,68635,0,0,477,10883,0,0;QS=3,0;MQSB=0.439649;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,147:6:0 0,12,143:4:0 +17 3776 . T 0 . DP=24;I16=15,7,0,0,838,32738,0,0,1152,64194,0,0,457,10375,0,0;QS=3,0;MQSB=0.225079;MQ0F=0 PL:DP:DV 0,39,229:13:0 0,15,149:5:0 0,12,152:4:0 +17 3777 . C 0 . DP=24;I16=15,9,0,0,864,32180,0,0,1218,66404,0,0,492,10998,0,0;QS=3,0;MQSB=0.705785;MQ0F=0 PL:DP:DV 0,39,220:13:0 0,18,160:6:0 0,15,168:5:0 +17 3778 . T 0 . DP=24;I16=14,9,0,0,859,32957,0,0,1208,66304,0,0,468,10372,0,0;QS=3,0;MQSB=0.836049;MQ0F=0 PL:DP:DV 0,36,227:12:0 0,18,157:6:0 0,15,167:5:0 +17 3779 . G 0 . DP=24;I16=15,9,0,0,844,31206,0,0,1218,66404,0,0,493,10971,0,0;QS=3,0;MQSB=0.705785;MQ0F=0 PL:DP:DV 0,39,220:13:0 0,18,152:6:0 0,15,167:5:0 +17 3780 . C 0 . DP=25;I16=14,10,0,0,829,29949,0,0,1268,69904,0,0,467,10295,0,0;QS=3,0;MQSB=0.765017;MQ0F=0 PL:DP:DV 0,39,235:13:0 0,18,144:6:0 0,15,169:5:0 +17 3781 . C 0 . DP=26;I16=16,10,0,0,939,34725,0,0,1315,71373,0,0,492,10896,0,0;QS=3,0;MQSB=0.541994;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,139:6:0 0,15,175:5:0 +17 3782 . T 0 . DP=26;I16=16,10,0,0,989,38031,0,0,1315,71373,0,0,493,10901,0,0;QS=3,0;MQSB=0.541994;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,169:6:0 0,15,176:5:0 +17 3783 . C 0 . DP=26;I16=16,10,0,0,941,34801,0,0,1315,71373,0,0,492,10836,0,0;QS=3,0;MQSB=0.541994;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,155:6:0 0,15,162:5:0 +17 3784 . T 0 . DP=27;I16=16,11,0,0,1001,38035,0,0,1375,74973,0,0,491,10801,0,0;QS=3,0;MQSB=0.467219;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,155:6:0 0,15,178:5:0 +17 3785 . G 0 . DP=28;I16=15,10,0,0,922,36426,0,0,1305,71273,0,0,450,9916,0,0;QS=3,0;MQSB=0.674458;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,125:5:0 0,15,179:5:0 +17 3786 . T 0 . DP=28;I16=16,11,0,0,935,35697,0,0,1375,74973,0,0,490,10774,0,0;QS=3,0;MQSB=0.467219;MQ0F=0 PL:DP:DV 0,48,250:16:0 0,18,145:6:0 0,15,186:5:0 +17 3787 . G 0 . DP=28;I16=16,11,0,0,963,37951,0,0,1375,74973,0,0,489,10781,0,0;QS=3,0;MQSB=0.467219;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,143:6:0 0,15,177:5:0 +17 3788 . G 0 . DP=26;I16=14,9,0,0,849,33683,0,0,1184,65386,0,0,459,10075,0,0;QS=3,0;MQSB=0.525788;MQ0F=0 PL:DP:DV 0,39,239:13:0 0,18,144:6:0 0,12,161:4:0 +17 3789 . G 0 . DP=26;I16=13,10,0,0,807,31019,0,0,1231,68535,0,0,438,9474,0,0;QS=3,0;MQSB=0.445672;MQ0F=0 PL:DP:DV 0,39,251:13:0 0,18,133:6:0 0,12,161:4:0 +17 3790 . T 0 . DP=26;I16=13,10,0,0,829,32293,0,0,1231,68535,0,0,435,9359,0,0;QS=3,0;MQSB=0.445672;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,150:6:0 0,12,159:4:0 +17 3791 . T 0 . DP=26;I16=15,10,0,0,887,34725,0,0,1301,72235,0,0,478,10336,0,0;QS=3,0;MQSB=0.382304;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,136:6:0 0,12,159:4:0 +17 3792 . G A, 0 . DP=26;I16=14,8,1,0,809,32805,38,1444,1175,66425,37,1369,417,8991,22,484;QS=2.92629,0.0737052,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.195278;BQB=1;MQ0F=0 PL:DP:DV 0,8,238,42,241,255:15:1 0,12,109,12,109,109:4:0 0,12,157,12,157,157:4:0 +17 3793 . A 0 . DP=26;I16=15,8,0,0,833,33775,0,0,1212,67794,0,0,435,9363,0,0;QS=3,0;MQSB=0.195278;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,93:4:0 0,12,159:4:0 +17 3794 . C 0 . DP=26;I16=15,9,0,0,845,33023,0,0,1241,68635,0,0,438,9324,0,0;QS=3,0;MQSB=0.439649;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,120:5:0 0,12,157:4:0 +17 3795 . C 0 . DP=26;I16=14,9,0,0,865,35649,0,0,1231,68535,0,0,408,8622,0,0;QS=3,0;MQSB=0.563599;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,132:5:0 0,12,161:4:0 +17 3796 . T 0 . DP=27;I16=15,11,0,0,964,38998,0,0,1361,75835,0,0,453,9821,0,0;QS=3,0;MQSB=0.334895;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,149:7:0 0,12,164:4:0 +17 3797 . A 0 . DP=27;I16=15,10,0,0,848,32392,0,0,1301,72235,0,0,424,9172,0,0;QS=3,0;MQSB=0.382304;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,124:6:0 0,12,159:4:0 +17 3798 . T 0 . DP=27;I16=14,11,0,0,921,37161,0,0,1301,72235,0,0,430,9554,0,0;QS=3,0;MQSB=0.283586;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,148:7:0 0,12,165:4:0 +17 3799 . T 0 . DP=27;I16=15,11,0,0,913,35929,0,0,1361,75835,0,0,439,9729,0,0;QS=3,0;MQSB=0.334895;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,21,150:7:0 0,12,161:4:0 +17 3800 . C 0 . DP=26;I16=13,10,0,0,866,36182,0,0,1181,65035,0,0,406,9092,0,0;QS=3,0;MQSB=0.272532;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,104:5:0 0,12,161:4:0 +17 3801 . T 0 . DP=23;I16=12,10,0,0,804,33600,0,0,1121,61435,0,0,430,9750,0,0;QS=3,0;MQSB=0.217267;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,99:5:0 0,9,133:3:0 +17 3802 . G 0 . DP=22;I16=10,9,0,0,730,30516,0,0,994,54486,0,0,380,8550,0,0;QS=3,0;MQSB=0.472367;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,106:4:0 0,9,130:3:0 +17 3803 . G 0 . DP=22;I16=11,9,0,0,703,27393,0,0,1051,57735,0,0,405,9241,0,0;QS=3,0;MQSB=0.372419;MQ0F=0 PL:DP:DV 0,39,249:13:0 0,12,92:4:0 0,9,129:3:0 +17 3804 . A 0 . DP=22;I16=11,9,0,0,740,30360,0,0,1051,57735,0,0,404,9274,0,0;QS=3,0;MQSB=0.372419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,98:4:0 0,9,132:3:0 +17 3805 . C 0 . DP=22;I16=12,9,0,0,737,29243,0,0,1061,57835,0,0,428,9950,0,0;QS=3,0;MQSB=0.262932;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,81:4:0 0,9,130:3:0 +17 3806 . A 0 . DP=22;I16=12,9,0,0,798,32550,0,0,1061,57835,0,0,426,9968,0,0;QS=3,0;MQSB=0.262932;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,105:4:0 0,9,128:3:0 +17 3807 . C 0 . DP=22;I16=10,9,0,0,664,25304,0,0,994,54486,0,0,377,8885,0,0;QS=3,0;MQSB=0.472367;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,83:4:0 0,9,115:3:0 +17 3808 . G 0 . DP=21;I16=9,9,0,0,653,25297,0,0,957,53117,0,0,375,8873,0,0;QS=3,0;MQSB=0.597145;MQ0F=0 PL:DP:DV 0,33,233:11:0 0,12,109:4:0 0,9,132:3:0 +17 3809 . T 0 . DP=22;I16=11,10,0,0,779,32151,0,0,1084,60066,0,0,416,9810,0,0;QS=3,0;MQSB=0.285029;MQ0F=0 PL:DP:DV 0,39,249:13:0 0,12,115:4:0 0,12,161:4:0 +17 3810 . C 0 . DP=23;I16=9,11,0,0,811,34815,0,0,1077,60317,0,0,369,8739,0,0;QS=3,0;MQSB=0.499893;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,112:4:0 0,12,153:4:0 +17 3811 . A C, 0 . DP=23;I16=9,11,2,0,777,32631,39,785,1077,60317,67,3349,367,8669,42,914;QS=2.94104,0.0589569,0;VDB=0.18;SGB=0.346553;RPB=0.425;MQB=0.25;MQSB=0.246128;BQB=0.025;MQ0F=0 PL:DP:DV 0,15,248,36,254,255:14:2 0,12,116,12,116,116:4:0 0,12,158,12,158,158:4:0 +17 3812 . T 0 . DP=23;I16=10,11,0,0,802,32860,0,0,1084,60066,0,0,405,9447,0,0;QS=3,0;MQSB=0.187115;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,114:4:0 0,12,160:4:0 +17 3813 . A 0 . DP=22;I16=10,11,0,0,815,35077,0,0,1084,60066,0,0,402,9330,0,0;QS=3,0;MQSB=0.187115;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,119:4:0 0,12,170:4:0 +17 3814 . G 0 . DP=21;I16=8,11,0,0,775,33731,0,0,1037,58597,0,0,375,8605,0,0;QS=3,0;MQSB=0.41781;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,113:4:0 0,12,163:4:0 +17 3815 . A 0 . DP=20;I16=8,11,0,0,708,29130,0,0,1010,57328,0,0,397,9049,0,0;QS=3,0;MQSB=0.373354;MQ0F=0 PL:DP:DV 0,33,239:11:0 0,12,110:4:0 0,12,162:4:0 +17 3816 . A 0 . DP=20;I16=8,11,0,0,729,31027,0,0,1010,57328,0,0,395,8933,0,0;QS=3,0;MQSB=0.373354;MQ0F=0 PL:DP:DV 0,33,248:11:0 0,12,104:4:0 0,12,160:4:0 +17 3817 . A 0 . DP=20;I16=8,11,0,0,752,31580,0,0,1010,57328,0,0,393,8833,0,0;QS=3,0;MQSB=0.373354;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,110:4:0 0,12,161:4:0 +17 3818 . T 0 . DP=20;I16=8,11,0,0,728,30466,0,0,1010,57328,0,0,391,8749,0,0;QS=3,0;MQSB=0.373354;MQ0F=0 PL:DP:DV 0,33,252:11:0 0,12,115:4:0 0,12,160:4:0 +17 3819 . A 0 . DP=21;I16=9,11,0,0,790,34094,0,0,1039,58169,0,0,389,8681,0,0;QS=3,0;MQSB=0.247381;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,121:4:0 0,12,167:4:0 +17 3820 . G 0 . DP=21;I16=9,11,0,0,788,33636,0,0,1039,58169,0,0,388,8630,0,0;QS=3,0;MQSB=0.247381;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,112:4:0 0,12,157:4:0 +17 3821 . A 0 . DP=22;I16=10,11,0,0,832,35864,0,0,1099,61769,0,0,387,8597,0,0;QS=3,0;MQSB=0.317882;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,115:4:0 0,12,168:4:0 +17 3822 . G 0 . DP=22;I16=10,11,0,0,810,33228,0,0,1099,61769,0,0,386,8532,0,0;QS=3,0;MQSB=0.317882;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,103:4:0 0,12,157:4:0 +17 3823 . T 0 . DP=22;I16=9,11,0,0,753,30705,0,0,1042,58520,0,0,380,8460,0,0;QS=3,0;MQSB=0.434285;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,102:4:0 0,12,163:4:0 +17 3824 . C 0 . DP=22;I16=10,11,0,0,802,32368,0,0,1099,61769,0,0,384,8456,0,0;QS=3,0;MQSB=0.317882;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,105:4:0 0,12,159:4:0 +17 3825 . C 0 . DP=23;I16=10,11,0,0,813,33955,0,0,1079,59889,0,0,379,8387,0,0;QS=3,0;MQSB=0.317882;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,130:5:0 0,12,157:4:0 +17 3826 . T 0 . DP=23;I16=11,11,0,0,827,34611,0,0,1136,63138,0,0,381,8357,0,0;QS=3,0;MQSB=0.232836;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,133:5:0 0,12,155:4:0 +17 3827 . G 0 . DP=23;I16=11,10,0,0,820,34130,0,0,1076,59538,0,0,355,7715,0,0;QS=3,0;MQSB=0.269397;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,121:4:0 0,12,162:4:0 +17 3828 . C 0 . DP=23;I16=11,10,0,0,805,33147,0,0,1076,59538,0,0,354,7720,0,0;QS=3,0;MQSB=0.269397;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,114:4:0 0,12,157:4:0 +17 3829 . A 0 . DP=22;I16=9,11,0,0,763,31295,0,0,1069,59789,0,0,369,8241,0,0;QS=3,0;MQSB=0.477679;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,132:5:0 0,12,158:4:0 +17 3830 . A 0 . DP=23;I16=11,11,0,0,825,32693,0,0,1136,63138,0,0,377,8321,0,0;QS=3,0;MQSB=0.232836;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,143:5:0 0,12,150:4:0 +17 3831 . C A, 0 . DP=23;I16=10,11,1,0,802,32198,14,196,1126,63038,10,100,370,8294,7,49;QS=2.97758,0.0224215,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.232836;BQB=1;MQ0F=0 PL:DP:DV 0,27,255,36,255,255:13:1 0,15,134,15,134,134:5:0 0,12,149,12,149,149:4:0 +17 3832 . A 0 . DP=24;I16=12,11,0,0,836,32436,0,0,1196,66738,0,0,377,8389,0,0;QS=3,0;MQSB=0.291845;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,136:5:0 0,12,139:4:0 +17 3833 . C 0 . DP=23;I16=10,11,0,0,690,24938,0,0,1076,59538,0,0,377,8409,0,0;QS=3,0;MQSB=0.175325;MQ0F=0 PL:DP:DV 0,36,249:12:0 0,15,113:5:0 0,12,131:4:0 +17 3834 . G 0 . DP=22;I16=9,10,0,0,684,26250,0,0,1037,58597,0,0,357,8079,0,0;QS=3,0;MQSB=0.124514;MQ0F=0 PL:DP:DV 0,33,242:11:0 0,12,122:4:0 0,12,156:4:0 +17 3835 . T 0 . DP=22;I16=10,11,0,0,773,30373,0,0,1076,59538,0,0,381,8475,0,0;QS=3,0;MQSB=0.175325;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,140:5:0 0,12,153:4:0 +17 3836 . G C, 0 . DP=24;I16=10,12,1,0,833,33183,14,196,1132,61648,10,100,378,8412,2,4;QS=2.97647,0.0235294,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.251407;BQB=1;MQ0F=0 PL:DP:DV 0,27,255,36,255,255:13:1 0,15,149,15,149,149:5:0 0,15,188,15,188,188:5:0 +17 3837 . G 0 . DP=24;I16=8,14,0,0,759,26931,0,0,1135,61999,0,0,399,8955,0,0;QS=3,0;MQSB=0.291667;MQ0F=0 PL:DP:DV 0,33,245:11:0 0,18,149:6:0 0,15,157:5:0 +17 3838 . C 0 . DP=24;I16=10,14,0,0,817,28975,0,0,1202,65348,0,0,409,8945,0,0;QS=3,0;MQSB=0.122456;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,143:6:0 0,15,148:5:0 +17 3839 . C 0 . DP=23;I16=9,13,0,0,688,22248,0,0,1132,61648,0,0,386,8238,0,0;QS=3,0;MQSB=0.248197;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,123:6:0 0,12,112:4:0 +17 3840 . G 0 . DP=23;I16=9,14,0,0,793,27941,0,0,1192,65248,0,0,413,8809,0,0;QS=3,0;MQSB=0.211072;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,160:6:0 0,15,146:5:0 +17 3841 . T 0 . DP=23;I16=9,14,0,0,867,33103,0,0,1192,65248,0,0,414,8734,0,0;QS=3,0;MQSB=0.211072;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,167:6:0 0,15,162:5:0 +17 3842 . C 0 . DP=23;I16=9,14,0,0,890,34728,0,0,1192,65248,0,0,415,8689,0,0;QS=3,0;MQSB=0.211072;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,167:6:0 0,15,159:5:0 +17 3843 . T 0 . DP=24;I16=9,14,0,0,896,35122,0,0,1192,65248,0,0,416,8674,0,0;QS=3,0;MQSB=0.211072;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,164:6:0 0,15,159:5:0 +17 3844 . G 0 . DP=26;I16=10,16,0,0,959,35715,0,0,1372,76048,0,0,442,9314,0,0;QS=3,0;MQSB=0.220358;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,177:7:0 0,18,172:6:0 +17 3845 . T 0 . DP=26;I16=10,16,0,0,970,36442,0,0,1372,76048,0,0,444,9310,0,0;QS=3,0;MQSB=0.220358;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,186:7:0 0,18,166:6:0 +17 3846 . G 0 . DP=27;I16=10,17,0,0,993,37297,0,0,1432,79648,0,0,446,9338,0,0;QS=3,0;MQSB=0.195223;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,175:7:0 0,21,172:7:0 +17 3847 . T 0 . DP=27;I16=10,16,0,0,952,35268,0,0,1372,76048,0,0,423,8723,0,0;QS=3,0;MQSB=0.220358;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,170:6:0 0,21,189:7:0 +17 3848 . C 0 . DP=27;I16=10,17,0,0,1025,39533,0,0,1432,79648,0,0,449,9341,0,0;QS=3,0;MQSB=0.195223;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,177:7:0 0,21,188:7:0 +17 3849 . T 0 . DP=27;I16=9,17,0,0,987,37685,0,0,1395,78279,0,0,450,9368,0,0;QS=3,0;MQSB=0.282527;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,179:7:0 0,21,190:7:0 +17 3850 . G 0 . DP=26;I16=9,17,0,0,957,35751,0,0,1395,78279,0,0,452,9428,0,0;QS=3,0;MQSB=0.282527;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,179:7:0 0,21,182:7:0 +17 3851 . G 0 . DP=26;I16=9,17,0,0,965,36475,0,0,1395,78279,0,0,453,9469,0,0;QS=3,0;MQSB=0.282527;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,177:7:0 0,21,183:7:0 +17 3852 . C 0 . DP=26;I16=9,16,0,0,921,34525,0,0,1335,74679,0,0,444,9440,0,0;QS=3,0;MQSB=0.310905;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,163:6:0 0,21,179:7:0 +17 3853 . T 0 . DP=28;I16=10,18,0,0,1050,40222,0,0,1484,82720,0,0,455,9641,0,0;QS=3,0;MQSB=0.515783;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,185:7:0 0,21,192:7:0 +17 3854 . T 0 . DP=28;I16=10,17,0,0,955,34605,0,0,1455,81879,0,0,451,9709,0,0;QS=3,0;MQSB=0.359211;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,171:6:0 0,18,178:6:0 +17 3855 . C 0 . DP=29;I16=10,18,0,0,992,36040,0,0,1515,85479,0,0,438,9264,0,0;QS=3,0;MQSB=0.331344;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,139:5:0 0,21,175:7:0 +17 3856 . T 0 . DP=30;I16=10,18,0,0,1033,38725,0,0,1546,88238,0,0,464,9982,0,0;QS=3,0;MQSB=0.190183;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,163:6:0 0,21,185:7:0 +17 3857 . C 0 . DP=30;I16=10,19,0,0,1077,40979,0,0,1575,89079,0,0,447,9505,0,0;QS=3,0;MQSB=0.306875;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,154:5:0 0,24,194:8:0 +17 3858 . T 0 . DP=31;I16=10,21,0,0,1141,42567,0,0,1695,96279,0,0,477,10255,0,0;QS=3,0;MQSB=0.266219;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,171:6:0 0,24,208:8:0 +17 3859 . C 0 . DP=32;I16=10,21,0,0,950,30078,0,0,1695,96279,0,0,484,10416,0,0;QS=3,0;MQSB=0.266219;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,136:6:0 0,24,156:8:0 +17 3860 . G 0 . DP=32;I16=10,22,0,0,1070,37794,0,0,1755,99879,0,0,516,11240,0,0;QS=3,0;MQSB=0.249261;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,154:6:0 0,27,209:9:0 +17 3861 . C 0 . DP=33;I16=11,20,0,0,1133,42547,0,0,1672,94048,0,0,517,11391,0,0;QS=3,0;MQSB=0.19205;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,162:6:0 0,24,199:8:0 +17 3862 . T 0 . DP=34;I16=11,22,0,0,1241,47443,0,0,1792,101248,0,0,526,11518,0,0;QS=3,0;MQSB=0.161533;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,185:7:0 0,27,221:9:0 +17 3863 . T 0 . DP=34;I16=12,22,0,0,1200,43542,0,0,1852,104848,0,0,541,11685,0,0;QS=3,0;MQSB=0.210327;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,199:7:0 0,27,213:9:0 +17 3864 . A 0 . DP=33;I16=11,22,0,0,1238,47448,0,0,1792,101248,0,0,550,11790,0,0;QS=3,0;MQSB=0.161533;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,210:7:0 0,27,230:9:0 +17 3865 . G 0 . DP=34;I16=11,23,0,0,1251,47113,0,0,1852,104848,0,0,559,11933,0,0;QS=3,0;MQSB=0.149071;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,200:7:0 0,27,212:9:0 +17 3866 . C 0 . DP=33;I16=11,21,0,0,1165,43545,0,0,1732,97648,0,0,545,11489,0,0;QS=3,0;MQSB=0.175751;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,189:7:0 0,24,197:8:0 +17 3867 . A 0 . DP=33;I16=11,22,0,0,1152,41510,0,0,1792,101248,0,0,580,12284,0,0;QS=3,0;MQSB=0.161533;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,188:7:0 0,27,195:9:0 +17 3868 . T 0 . DP=33;I16=11,22,0,0,1255,48141,0,0,1792,101248,0,0,590,12494,0,0;QS=3,0;MQSB=0.161533;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,202:7:0 0,27,221:9:0 +17 3869 . C 0 . DP=33;I16=11,21,0,0,1169,43987,0,0,1732,97648,0,0,589,12623,0,0;QS=3,0;MQSB=0.175751;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,164:6:0 0,27,211:9:0 +17 3870 . T 0 . DP=34;I16=11,23,0,0,1262,47808,0,0,1852,104848,0,0,608,12932,0,0;QS=3,0;MQSB=0.149071;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,215:8:0 0,27,211:9:0 +17 3871 . T 0 . DP=36;I16=11,25,0,0,1341,50655,0,0,1972,112048,0,0,617,13157,0,0;QS=3,0;MQSB=0.128391;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,221:8:0 0,27,223:9:0 +17 3872 . G 0 . DP=36;I16=11,25,0,0,1287,47095,0,0,1972,112048,0,0,626,13322,0,0;QS=3,0;MQSB=0.128391;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,211:8:0 0,27,200:9:0 +17 3873 . T 0 . DP=35;I16=10,24,0,0,1242,46680,0,0,1852,104848,0,0,626,13428,0,0;QS=3,0;MQSB=0.0982034;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,194:7:0 0,24,212:8:0 +17 3874 . T 0 . DP=36;I16=12,24,0,0,1290,47660,0,0,1972,112048,0,0,646,13774,0,0;QS=3,0;MQSB=0.182088;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,24,228:8:0 0,24,204:8:0 +17 3875 . T 0 . DP=37;I16=13,24,0,0,1324,48418,0,0,2029,115297,0,0,657,14061,0,0;QS=3,0;MQSB=0.117872;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,231:8:0 0,24,197:8:0 +17 3876 . C 0 . DP=37;I16=13,22,0,0,1248,45354,0,0,1909,108097,0,0,623,13325,0,0;QS=3,0;MQSB=0.140806;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,196:7:0 0,24,180:8:0 +17 3877 . C 0 . DP=37;I16=13,24,0,0,1363,51201,0,0,2029,115297,0,0,681,14765,0,0;QS=3,0;MQSB=0.117872;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,217:8:0 0,24,196:8:0 +17 3878 . A 0 . DP=37;I16=13,23,0,0,1309,48045,0,0,1969,111697,0,0,670,14654,0,0;QS=3,0;MQSB=0.128568;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,24,218:8:0 0,24,188:8:0 +17 3879 . A 0 . DP=38;I16=14,24,0,0,1453,56567,0,0,2066,116666,0,0,703,15543,0,0;QS=3,0;MQSB=0.076112;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,226:8:0 0,24,206:8:0 +17 3880 . G 0 . DP=37;I16=14,22,0,0,1311,48735,0,0,1946,109466,0,0,689,15267,0,0;QS=3,0;MQSB=0.094094;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,24,209:8:0 0,24,183:8:0 +17 3881 . G 0 . DP=37;I16=14,21,0,0,1200,42778,0,0,1886,105866,0,0,690,15578,0,0;QS=3,0;MQSB=0.105399;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,18,178:6:0 0,24,174:8:0 +17 3882 . T 0 . DP=37;I16=14,21,0,0,1192,42352,0,0,1886,105866,0,0,684,15348,0,0;QS=3,0;MQSB=0.105399;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,21,189:7:0 0,21,178:7:0 +17 3883 . C 0 . DP=38;I16=15,22,0,0,1295,46659,0,0,2006,113066,0,0,717,16279,0,0;QS=3,0;MQSB=0.124405;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,205:8:0 0,24,171:8:0 +17 3884 . C 0 . DP=39;I16=16,23,0,0,1363,49387,0,0,2103,118035,0,0,749,17141,0,0;QS=3,0;MQSB=0.0760633;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,202:8:0 0,27,212:9:0 +17 3885 . T 0 . DP=40;I16=16,24,0,0,1445,53663,0,0,2163,121635,0,0,754,17262,0,0;QS=3,0;MQSB=0.0679472;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,24,219:8:0 0,27,214:9:0 +17 3886 . C 0 . DP=39;I16=16,23,0,0,1370,49762,0,0,2103,118035,0,0,761,17421,0,0;QS=3,0;MQSB=0.0760633;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,24,199:8:0 0,24,191:8:0 +17 3887 . C 0 . DP=39;I16=16,23,0,0,1364,49222,0,0,2103,118035,0,0,767,17567,0,0;QS=3,0;MQSB=0.0760633;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,24,194:8:0 0,24,201:8:0 +17 3888 . C 0 . DP=39;I16=15,23,0,0,1387,51885,0,0,2043,114435,0,0,747,17073,0,0;QS=3,0;MQSB=0.0555905;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,195:8:0 0,24,208:8:0 +17 3889 . A 0 . DP=38;I16=15,23,0,0,1364,49918,0,0,2066,116666,0,0,777,17811,0,0;QS=3,0;MQSB=0.112471;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,202:8:0 0,24,218:8:0 +17 3890 . C 0 . DP=38;I16=14,23,0,0,1362,51064,0,0,2006,113066,0,0,757,17329,0,0;QS=3,0;MQSB=0.0844255;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,203:8:0 0,24,216:8:0 +17 3891 . A 0 . DP=39;I16=15,24,0,0,1466,56312,0,0,2126,120266,0,0,786,18076,0,0;QS=3,0;MQSB=0.102114;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,203:8:0 0,27,239:9:0 +17 3892 . G 0 . DP=38;I16=15,23,0,0,1340,48838,0,0,2066,116666,0,0,792,18226,0,0;QS=3,0;MQSB=0.112471;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,186:8:0 0,27,208:9:0 +17 3893 . T 0 . DP=39;I16=15,24,0,0,1348,48170,0,0,2126,120266,0,0,798,18404,0,0;QS=3,0;MQSB=0.102114;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,196:8:0 0,27,212:9:0 +17 3894 . G 0 . DP=39;I16=15,23,0,0,1364,49900,0,0,2066,116666,0,0,779,17937,0,0;QS=3,0;MQSB=0.112471;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,202:8:0 0,27,208:9:0 +17 3895 . T 0 . DP=39;I16=15,24,0,0,1375,49773,0,0,2126,120266,0,0,810,18752,0,0;QS=3,0;MQSB=0.102114;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,202:8:0 0,27,225:9:0 +17 3896 . A 0 . DP=40;I16=15,24,0,0,1468,57326,0,0,2126,120266,0,0,815,18923,0,0;QS=3,0;MQSB=0.102114;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,224:8:0 0,27,233:9:0 +17 3897 . G 0 . DP=40;I16=15,24,0,0,1468,56812,0,0,2126,120266,0,0,819,19021,0,0;QS=3,0;MQSB=0.102114;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,21,199:7:0 0,30,234:10:0 +17 3898 . C 0 . DP=40;I16=15,23,0,0,1487,59351,0,0,2066,116666,0,0,813,19023,0,0;QS=3,0;MQSB=0.112471;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,18,186:6:0 0,30,238:10:0 +17 3899 . A 0 . DP=40;I16=15,24,0,0,1449,55055,0,0,2126,120266,0,0,829,19293,0,0;QS=3,0;MQSB=0.102114;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,21,191:7:0 0,30,231:10:0 +17 3900 . T 0 . DP=40;I16=15,24,0,0,1458,55516,0,0,2126,120266,0,0,833,19417,0,0;QS=3,0;MQSB=0.102114;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,21,197:7:0 0,30,240:10:0 +17 3901 . G 0 . DP=40;I16=14,22,0,0,1303,48245,0,0,1969,111697,0,0,761,17639,0,0;QS=3,0;MQSB=0.180757;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,18,154:6:0 0,27,218:9:0 +17 3902 . C 0 . DP=40;I16=15,24,0,0,1436,55412,0,0,2126,120266,0,0,837,19537,0,0;QS=3,0;MQSB=0.102114;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,21,166:7:0 0,30,217:10:0 +17 3903 . A 0 . DP=42;I16=15,24,0,0,1299,45567,0,0,2089,117417,0,0,814,19008,0,0;QS=3,0;MQSB=0.0901152;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,175:8:0 0,30,204:10:0 +17 3904 . C 0 . DP=42;I16=15,24,0,0,1439,54545,0,0,2086,117066,0,0,815,19113,0,0;QS=3,0;MQSB=0.0426917;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,191:8:0 0,30,244:10:0 +17 3905 . C 0 . DP=42;I16=15,25,0,0,1572,63314,0,0,2146,120666,0,0,822,19192,0,0;QS=3,0;MQSB=0.0381122;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,24,212:8:0 0,33,255:11:0 +17 3906 . T 0 . DP=42;I16=16,25,0,0,1593,63039,0,0,2206,124266,0,0,846,19758,0,0;QS=3,0;MQSB=0.0536599;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,210:8:0 0,33,253:11:0 +17 3907 . G 0 . DP=42;I16=16,25,0,0,1558,60192,0,0,2206,124266,0,0,846,19776,0,0;QS=3,0;MQSB=0.0536599;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,203:8:0 0,33,249:11:0 +17 3908 . C 0 . DP=42;I16=16,25,0,0,1514,58968,0,0,2206,124266,0,0,845,19777,0,0;QS=3,0;MQSB=0.0536599;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,24,193:8:0 0,33,244:11:0 +17 3909 . T 0 . DP=43;I16=16,25,0,0,1491,55895,0,0,2201,123691,0,0,835,19697,0,0;QS=3,0;MQSB=0.0757469;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,24,202:8:0 0,30,237:10:0 +17 3910 . A 0 . DP=40;I16=16,23,0,0,1432,53926,0,0,2081,116491,0,0,844,19724,0,0;QS=3,0;MQSB=0.0949554;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,21,193:7:0 0,30,224:10:0 +17 3911 . C 0 . DP=40;I16=16,23,0,0,1440,55290,0,0,2081,116491,0,0,843,19613,0,0;QS=3,0;MQSB=0.0949554;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,21,184:7:0 0,30,214:10:0 +17 3912 . A C, 0 . DP=41;I16=17,22,0,1,1358,49508,16,256,2081,116491,60,3600,830,19358,11,121;QS=2.95181,0.0481928,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.125266;BQB=1;MQ0F=0 PL:DP:DV 0,69,255,69,255,255:23:0 0,21,166,21,166,166:7:0 0,14,202,27,205,208:10:1 +17 3913 . C 0 . DP=40;I16=16,23,0,0,1494,59096,0,0,2081,116491,0,0,824,19100,0,0;QS=3,0;MQSB=0.0949554;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,21,183:7:0 0,30,234:10:0 +17 3914 . T 0 . DP=42;I16=16,24,0,0,1512,59342,0,0,2141,120091,0,0,823,19007,0,0;QS=3,0;MQSB=0.0846181;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,21,192:7:0 0,30,228:10:0 +17 3915 . C 0 . DP=42;I16=16,24,0,0,1537,60953,0,0,2141,120091,0,0,799,18321,0,0;QS=3,0;MQSB=0.0846181;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,18,176:6:0 0,30,229:10:0 +17 3916 . C 0 . DP=42;I16=16,25,0,0,1618,66342,0,0,2201,123691,0,0,825,18919,0,0;QS=3,0;MQSB=0.0757469;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,21,190:7:0 0,30,251:10:0 +17 3917 . T 0 . DP=43;I16=16,25,0,0,1601,65219,0,0,2201,123691,0,0,825,18875,0,0;QS=3,0;MQSB=0.0757469;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,21,191:7:0 0,30,254:10:0 +17 3918 . T 0 . DP=43;I16=16,25,0,0,1541,60711,0,0,2201,123691,0,0,801,18239,0,0;QS=3,0;MQSB=0.0757469;MQ0F=0 PL:DP:DV 0,75,255:25:0 0,18,179:6:0 0,30,254:10:0 +17 3919 . C 0 . DP=42;I16=15,26,0,0,1621,66337,0,0,2232,126450,0,0,826,18786,0,0;QS=3,0;MQSB=0.110793;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,21,200:7:0 0,30,242:10:0 +17 3920 . T 0 . DP=42;I16=15,26,0,0,1605,64327,0,0,2232,126450,0,0,825,18691,0,0;QS=3,0;MQSB=0.110793;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,21,207:7:0 0,30,251:10:0 +17 3921 . T 0 . DP=42;I16=15,26,0,0,1519,58507,0,0,2232,126450,0,0,824,18630,0,0;QS=3,0;MQSB=0.110793;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,21,201:7:0 0,30,242:10:0 +17 3922 . A 0 . DP=42;I16=14,26,0,0,1539,61289,0,0,2195,125081,0,0,819,18545,0,0;QS=3,0;MQSB=0.168991;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,18,179:6:0 0,30,244:10:0 +17 3923 . G 0 . DP=41;I16=14,25,0,0,1515,60945,0,0,2135,121481,0,0,792,17834,0,0;QS=3,0;MQSB=0.182501;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,18,172:6:0 0,30,240:10:0 +17 3924 . G 0 . DP=41;I16=13,26,0,0,1524,61106,0,0,2135,121481,0,0,808,18356,0,0;QS=3,0;MQSB=0.128469;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,18,158:6:0 0,30,247:10:0 +17 3925 . G 0 . DP=41;I16=14,25,0,0,1425,55687,0,0,2135,121481,0,0,788,17758,0,0;QS=3,0;MQSB=0.182501;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,15,134:5:0 0,30,245:10:0 +17 3926 . C 0 . DP=41;I16=14,26,0,0,1512,59674,0,0,2195,125081,0,0,811,18393,0,0;QS=3,0;MQSB=0.168991;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,18,152:6:0 0,30,237:10:0 +17 3927 . T 0 . DP=41;I16=14,26,0,0,1512,59566,0,0,2195,125081,0,0,808,18384,0,0;QS=3,0;MQSB=0.168991;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,18,160:6:0 0,30,237:10:0 +17 3928 . G 0 . DP=41;I16=14,25,0,0,1479,58495,0,0,2135,121481,0,0,779,17731,0,0;QS=3,0;MQSB=0.182501;MQ0F=0 PL:DP:DV 0,72,255:24:0 0,18,149:6:0 0,27,233:9:0 +17 3929 . A 0 . DP=41;I16=13,26,0,0,1452,56436,0,0,2135,121481,0,0,796,18256,0,0;QS=3,0;MQSB=0.128469;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,18,161:6:0 0,30,220:10:0 +17 3930 . T 0 . DP=40;I16=13,25,0,0,1387,52929,0,0,2078,118232,0,0,767,17521,0,0;QS=3,0;MQSB=0.25797;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,15,149:5:0 0,30,224:10:0 +17 3931 . A 0 . DP=40;I16=13,25,0,0,1387,52877,0,0,2078,118232,0,0,761,17439,0,0;QS=3,0;MQSB=0.25797;MQ0F=0 PL:DP:DV 0,69,255:23:0 0,18,166:6:0 0,27,222:9:0 +17 3932 . T 0 . DP=39;I16=12,26,0,0,1394,53644,0,0,2078,118232,0,0,780,17964,0,0;QS=3,0;MQSB=0.190372;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,18,161:6:0 0,30,231:10:0 +17 3933 . T 0 . DP=38;I16=12,24,0,0,1389,54743,0,0,1958,111032,0,0,752,17366,0,0;QS=3,0;MQSB=0.218161;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,18,166:6:0 0,24,220:8:0 +17 3934 . C 0 . DP=38;I16=12,25,0,0,1395,54915,0,0,2018,114632,0,0,768,17758,0,0;QS=3,0;MQSB=0.203497;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,18,152:6:0 0,27,209:9:0 +17 3935 . C 0 . DP=38;I16=12,24,0,0,1239,44621,0,0,1958,111032,0,0,737,17075,0,0;QS=3,0;MQSB=0.218161;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,15,134:5:0 0,27,170:9:0 +17 3936 . A G, 0 . DP=37;I16=5,6,6,17,424,16384,801,30271,609,34563,1314,77018,225,5325,511,11851;QS=0.87994,2.12006,0;VDB=0.0574114;SGB=-4.60123;RPB=0.741697;MQB=0.812605;MQSB=0.143788;BQB=0.883831;MQ0F=0 PL:DP:DV 233,0,206,255,239,255:20:11 77,0,58,83,70,141:6:4 196,24,0,196,24,196:8:8 +17 3937 . C 0 . DP=36;I16=11,24,0,0,1155,39875,0,0,1952,112422,0,0,745,17291,0,0;QS=3,0;MQSB=0.219636;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,18,143:6:0 0,24,156:8:0 +17 3938 . G 0 . DP=35;I16=11,23,0,0,1155,41761,0,0,1892,108822,0,0,737,17079,0,0;QS=3,0;MQSB=0.231054;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,15,119:5:0 0,24,176:8:0 +17 3939 . C 0 . DP=35;I16=11,22,0,0,1273,50651,0,0,1832,105222,0,0,703,16221,0,0;QS=3,0;MQSB=0.243713;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,15,135:5:0 0,21,174:7:0 +17 3940 . A 0 . DP=35;I16=11,22,0,0,1148,42754,0,0,1832,105222,0,0,691,15867,0,0;QS=3,0;MQSB=0.243713;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,15,117:5:0 0,21,163:7:0 +17 3941 . C 0 . DP=35;I16=11,22,0,0,1216,47488,0,0,1832,105222,0,0,688,15892,0,0;QS=3,0;MQSB=0.243713;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,15,133:5:0 0,21,181:7:0 +17 3942 . C 0 . DP=35;I16=11,23,0,0,1336,54166,0,0,1892,108822,0,0,690,15772,0,0;QS=3,0;MQSB=0.231054;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,15,140:5:0 0,24,195:8:0 +17 3943 . T 0 . DP=35;I16=11,23,0,0,1296,51618,0,0,1892,108822,0,0,676,15406,0,0;QS=3,0;MQSB=0.231054;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,15,142:5:0 0,24,195:8:0 +17 3944 . G 0 . DP=34;I16=10,22,0,0,1199,46445,0,0,1803,104381,0,0,654,14954,0,0;QS=3,0;MQSB=0.1117;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,149:5:0 0,24,195:8:0 +17 3945 . C 0 . DP=33;I16=10,22,0,0,1256,51226,0,0,1772,101622,0,0,649,14657,0,0;QS=3,0;MQSB=0.187579;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,142:5:0 0,21,177:7:0 +17 3946 . T 0 . DP=33;I16=10,21,0,0,1170,45884,0,0,1712,98022,0,0,609,13599,0,0;QS=3,0;MQSB=0.199344;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,144:5:0 0,18,158:6:0 +17 3947 . A 0 . DP=32;I16=10,21,0,0,1094,41048,0,0,1712,98022,0,0,620,13820,0,0;QS=3,0;MQSB=0.199344;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,15,128:5:0 0,18,149:6:0 +17 3948 . C 0 . DP=32;I16=10,20,0,0,1134,45104,0,0,1652,94422,0,0,596,13344,0,0;QS=3,0;MQSB=0.212591;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,105:4:0 0,18,155:6:0 +17 3949 . A C, 0 . DP=32;I16=10,17,0,1,1027,39909,24,576,1472,83622,60,3600,541,12211,25,625;QS=2.85093,0.149068,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.244621;BQB=1;MQ0F=0 PL:DP:DV 0,60,255,60,255,255:20:0 0,9,89,9,89,89:3:0 9,0,107,21,110,124:5:1 +17 3950 . C 0 . DP=33;I16=11,21,0,0,1191,46247,0,0,1772,101622,0,0,576,12680,0,0;QS=3,0;MQSB=0.257801;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,15,118:5:0 0,18,168:6:0 +17 3951 . T 0 . DP=34;I16=12,19,0,0,1148,44272,0,0,1712,98022,0,0,530,11670,0,0;QS=3,0;MQSB=0.354733;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,15,146:5:0 0,15,152:5:0 +17 3952 . C 0 . DP=35;I16=13,20,0,0,1176,43762,0,0,1832,105222,0,0,545,12025,0,0;QS=3,0;MQSB=0.394875;MQ0F=0 PL:DP:DV 0,66,255:22:0 0,18,158:6:0 0,15,143:5:0 +17 3953 . C 0 . DP=34;I16=13,20,0,0,1246,48436,0,0,1863,107981,0,0,538,11772,0,0;QS=3,0;MQSB=0.252983;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,18,163:6:0 0,18,168:6:0 +17 3954 . T 0 . DP=33;I16=13,19,0,0,1195,45815,0,0,1803,104381,0,0,526,11438,0,0;QS=3,0;MQSB=0.264585;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,18,171:6:0 0,18,167:6:0 +17 3955 . T 0 . DP=32;I16=13,18,0,0,1180,46092,0,0,1743,100781,0,0,515,11139,0,0;QS=3,0;MQSB=0.277468;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,173:6:0 0,18,174:6:0 +17 3956 . C 0 . DP=32;I16=13,18,0,0,1181,47021,0,0,1743,100781,0,0,504,10874,0,0;QS=3,0;MQSB=0.277468;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,167:6:0 0,18,167:6:0 +17 3957 . T 0 . DP=31;I16=13,17,0,0,1153,46051,0,0,1683,97181,0,0,494,10642,0,0;QS=3,0;MQSB=0.291833;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,161:6:0 0,15,162:5:0 +17 3958 . T 0 . DP=31;I16=13,16,0,0,1070,40600,0,0,1623,93581,0,0,483,10393,0,0;QS=3,0;MQSB=0.307929;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,139:5:0 0,15,157:5:0 +17 3959 . A 0 . DP=30;I16=14,15,0,0,1062,39758,0,0,1623,93581,0,0,474,10176,0,0;QS=3,0;MQSB=0.377103;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,118:4:0 0,15,154:5:0 +17 3960 . T 0 . DP=30;I16=14,15,0,0,995,36027,0,0,1623,93581,0,0,464,9892,0,0;QS=3,0;MQSB=0.377103;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,105:4:0 0,15,142:5:0 +17 3961 . G 0 . DP=29;I16=12,16,0,0,1067,40899,0,0,1586,92212,0,0,457,9739,0,0;QS=3,0;MQSB=0.455864;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,114:4:0 0,12,122:4:0 +17 3962 . G 0 . DP=29;I16=13,16,0,0,1025,37125,0,0,1623,93581,0,0,471,10053,0,0;QS=3,0;MQSB=0.307929;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,108:4:0 0,15,144:5:0 +17 3963 . C 0 . DP=28;I16=13,15,0,0,1040,39100,0,0,1563,89981,0,0,463,9871,0,0;QS=3,0;MQSB=0.326055;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,12,111:4:0 0,12,126:4:0 +17 3964 . T 0 . DP=27;I16=12,15,0,0,1036,39928,0,0,1503,86381,0,0,456,9720,0,0;QS=3,0;MQSB=0.273507;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,9,94:3:0 0,12,133:4:0 +17 3965 . G 0 . DP=26;I16=12,14,0,0,993,38165,0,0,1443,82781,0,0,450,9598,0,0;QS=3,0;MQSB=0.29215;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,9,92:3:0 0,12,134:4:0 +17 3966 . A 0 . DP=26;I16=12,13,0,0,930,34834,0,0,1406,81412,0,0,432,9310,0,0;QS=3,0;MQSB=0.520812;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,90:3:0 0,12,140:4:0 +17 3967 . T 0 . DP=26;I16=12,13,0,0,900,32830,0,0,1406,81412,0,0,421,9001,0,0;QS=3,0;MQSB=0.520812;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,9,90:3:0 0,9,100:3:0 +17 3968 . A 0 . DP=25;I16=12,13,0,0,885,31773,0,0,1406,81412,0,0,415,8853,0,0;QS=3,0;MQSB=0.520812;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,9,90:3:0 0,9,99:3:0 +17 3969 . T 0 . DP=24;I16=11,13,0,0,886,32972,0,0,1369,80043,0,0,410,8736,0,0;QS=3,0;MQSB=0.702671;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,85:3:0 0,9,108:3:0 +17 3970 . T 0 . DP=24;I16=11,13,0,0,861,31313,0,0,1369,80043,0,0,405,8649,0,0;QS=3,0;MQSB=0.702671;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,83:3:0 0,9,104:3:0 +17 3971 . C 0 . DP=22;I16=11,11,0,0,815,30625,0,0,1249,72843,0,0,402,8590,0,0;QS=3,0;MQSB=0.751921;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,57:2:0 0,9,103:3:0 +17 3972 . C 0 . DP=22;I16=11,11,0,0,812,30486,0,0,1249,72843,0,0,399,8557,0,0;QS=3,0;MQSB=0.751921;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,55:2:0 0,9,96:3:0 +17 3973 . A 0 . DP=22;I16=11,11,0,0,795,28873,0,0,1249,72843,0,0,395,8501,0,0;QS=3,0;MQSB=0.751921;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,52:2:0 0,9,97:3:0 +17 3974 . C 0 . DP=22;I16=11,11,0,0,729,24447,0,0,1249,72843,0,0,392,8472,0,0;QS=3,0;MQSB=0.751921;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,55:2:0 0,9,78:3:0 +17 3975 . G 0 . DP=22;I16=11,11,0,0,717,24525,0,0,1249,72843,0,0,390,8470,0,0;QS=3,0;MQSB=0.751921;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,46:2:0 0,9,96:3:0 +17 3976 . C 0 . DP=22;I16=11,11,0,0,816,30652,0,0,1249,72843,0,0,387,8445,0,0;QS=3,0;MQSB=0.751921;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,55:2:0 0,9,97:3:0 +17 3977 . A 0 . DP=23;I16=11,11,0,0,740,25384,0,0,1249,72843,0,0,382,8346,0,0;QS=3,0;MQSB=0.751921;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,48:2:0 0,9,90:3:0 +17 3978 . C 0 . DP=23;I16=11,12,0,0,769,26631,0,0,1309,76443,0,0,377,8223,0,0;QS=3,0;MQSB=0.726094;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,47:2:0 0,9,103:3:0 +17 3979 . C 0 . DP=21;I16=9,11,0,0,744,28160,0,0,1152,67874,0,0,361,7905,0,0;QS=3,0;MQSB=0.885207;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,51:2:0 0,9,104:3:0 +17 3980 . T 0 . DP=21;I16=10,11,0,0,756,27872,0,0,1212,71474,0,0,367,7855,0,0;QS=3,0;MQSB=0.914611;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,51:2:0 0,9,98:3:0 +17 3981 . G 0 . DP=21;I16=10,11,0,0,785,29641,0,0,1212,71474,0,0,362,7710,0,0;QS=3,0;MQSB=0.914611;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,50:2:0 0,9,93:3:0 +17 3982 . C 0 . DP=21;I16=10,11,0,0,779,29495,0,0,1212,71474,0,0,357,7591,0,0;QS=3,0;MQSB=0.914611;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,55:2:0 0,9,97:3:0 +17 3983 . T 0 . DP=20;I16=9,11,0,0,720,26274,0,0,1155,68225,0,0,353,7497,0,0;QS=3,0;MQSB=0.993528;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,57:2:0 0,9,93:3:0 +17 3984 . A 0 . DP=21;I16=10,11,0,0,739,26279,0,0,1192,69594,0,0,348,7378,0,0;QS=3,0;MQSB=0.885602;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,53:2:0 0,9,80:3:0 +17 3985 . C 0 . DP=20;I16=10,10,0,0,728,26998,0,0,1132,65994,0,0,344,7234,0,0;QS=3,0;MQSB=0.902256;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,55:2:0 0,9,91:3:0 +17 3986 . A 0 . DP=20;I16=10,10,0,0,685,23815,0,0,1132,65994,0,0,340,7114,0,0;QS=3,0;MQSB=0.902256;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,56:2:0 0,9,84:3:0 +17 3987 . C 0 . DP=20;I16=10,10,0,0,736,28118,0,0,1132,65994,0,0,336,7018,0,0;QS=3,0;MQSB=0.902256;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,55:2:0 0,9,94:3:0 +17 3988 . T 0 . DP=21;I16=10,10,0,0,741,27797,0,0,1132,65994,0,0,332,6946,0,0;QS=3,0;MQSB=0.902256;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,58:2:0 0,9,91:3:0 +17 3989 . C 0 . DP=21;I16=10,11,0,0,729,26185,0,0,1192,69594,0,0,327,6801,0,0;QS=3,0;MQSB=0.885602;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,55:2:0 0,9,88:3:0 +17 3990 . C 0 . DP=21;I16=10,11,0,0,766,28674,0,0,1192,69594,0,0,322,6686,0,0;QS=3,0;MQSB=0.885602;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,55:2:0 0,9,95:3:0 +17 3991 . T 0 . DP=20;I16=9,11,0,0,729,27311,0,0,1132,65994,0,0,318,6600,0,0;QS=3,0;MQSB=0.850154;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,55:2:0 0,9,89:3:0 +17 3992 . T 0 . DP=19;I16=9,10,0,0,667,24173,0,0,1072,62394,0,0,313,6441,0,0;QS=3,0;MQSB=0.868634;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,56:2:0 0,6,72:2:0 +17 3993 . C 0 . DP=18;I16=9,9,0,0,701,27529,0,0,1012,58794,0,0,309,6307,0,0;QS=3,0;MQSB=0.888755;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,59:2:0 0,6,70:2:0 +17 3994 . T 0 . DP=19;I16=10,9,0,0,718,27520,0,0,1049,60163,0,0,305,6197,0,0;QS=3,0;MQSB=0.716531;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,58:2:0 0,6,72:2:0 +17 3995 . T 0 . DP=19;I16=9,9,0,0,641,23025,0,0,989,56563,0,0,277,5487,0,0;QS=3,0;MQSB=0.650623;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,53:2:0 0,6,69:2:0 +17 3996 . A 0 . DP=19;I16=9,9,0,0,665,24815,0,0,989,56563,0,0,274,5428,0,0;QS=3,0;MQSB=0.650623;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,54:2:0 0,6,73:2:0 +17 3997 . G C, 0 . DP=19;I16=10,8,0,1,645,23703,21,441,989,56563,60,3600,287,5843,6,36;QS=2.96023,0.0397727,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.716531;BQB=1;MQ0F=0 PL:DP:DV 0,24,255,42,255,255:15:1 0,6,57,6,57,57:2:0 0,6,60,6,60,60:2:0 +17 3998 . G 0 . DP=18;I16=9,8,0,0,626,23710,0,0,929,52963,0,0,265,5203,0,0;QS=3,0;MQSB=0.687289;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,6,58:2:0 0,3,36:1:0 +17 3999 . G A, 0 . DP=18;I16=9,7,0,1,596,22974,37,1369,869,49363,60,3600,263,5387,4,16;QS=2.92871,0.0712909,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.687289;BQB=1;MQ0F=0 PL:DP:DV 0,5,255,39,255,255:14:1 0,6,56,6,56,56:2:0 0,3,38,3,38,38:1:0 +17 4000 . C 0 . DP=18;I16=10,8,0,0,669,25389,0,0,989,56563,0,0,283,5753,0,0;QS=3,0;MQSB=0.751866;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,55:2:0 0,3,36:1:0 +17 4001 . T 0 . DP=18;I16=10,8,0,0,680,26006,0,0,989,56563,0,0,279,5727,0,0;QS=3,0;MQSB=0.751866;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,56:2:0 0,3,33:1:0 +17 4002 . G 0 . DP=17;I16=10,7,0,0,621,23281,0,0,929,52963,0,0,276,5724,0,0;QS=2,0;MQSB=0.79189;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,44:2:0 0,0,0:0:0 +17 4003 . A 0 . DP=17;I16=10,7,0,0,597,21507,0,0,929,52963,0,0,272,5692,0,0;QS=2,0;MQSB=0.79189;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,6,55:2:0 0,0,0:0:0 +17 4004 . T 0 . DP=15;I16=9,6,0,0,527,19031,0,0,849,48963,0,0,270,5678,0,0;QS=2,0;MQSB=0.957526;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,40:1:0 0,0,0:0:0 +17 4005 . A 0 . DP=15;I16=8,5,0,0,479,17731,0,0,729,41763,0,0,237,5195,0,0;QS=2,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,35:1:0 0,0,0:0:0 +17 4006 . T 0 . DP=15;I16=9,6,0,0,554,20776,0,0,849,48963,0,0,266,5698,0,0;QS=2,0;MQSB=0.957526;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,40:1:0 0,0,0:0:0 +17 4007 . T G, 0 . DP=15;I16=9,5,0,1,490,17810,15,225,789,45363,60,3600,245,5371,19,361;QS=1.96746,0.032538,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.957526;BQB=1;MQ0F=0 PL:DP:DV 0,26,255,39,255,255:14:1 0,3,41,3,41,41:1:0 0,0,0,0,0,0:0:0 +17 4008 . C 0 . DP=15;I16=9,6,0,0,488,16890,0,0,849,48963,0,0,262,5782,0,0;QS=2,0;MQSB=0.957526;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,3,30:1:0 0,0,0:0:0 +17 4009 . C 0 . DP=14;I16=9,5,0,0,524,20150,0,0,794,45938,0,0,261,5847,0,0;QS=2,0;MQSB=0.800737;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,40:1:0 0,0,0:0:0 +17 4010 . A 0 . DP=14;I16=9,5,0,0,523,19731,0,0,794,45938,0,0,259,5875,0,0;QS=2,0;MQSB=0.800737;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,41:1:0 0,0,0:0:0 +17 4011 . C 0 . DP=14;I16=9,5,0,0,489,17613,0,0,794,45938,0,0,257,5915,0,0;QS=2,0;MQSB=0.800737;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,3,41:1:0 0,0,0:0:0 +17 4012 . A 0 . DP=14;I16=7,5,0,0,365,11867,0,0,674,38738,0,0,223,5293,0,0;QS=2,0;MQSB=0.6821;MQ0F=0 PL:DP:DV 0,33,231:11:0 0,3,30:1:0 0,0,0:0:0 +17 4013 . C 0 . DP=14;I16=8,5,0,0,451,15885,0,0,734,42338,0,0,247,5995,0,0;QS=2,0;MQSB=0.765017;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,3,37:1:0 0,0,0:0:0 +17 4014 . A 0 . DP=12;I16=8,2,0,0,358,13372,0,0,554,31538,0,0,222,5404,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,213:9:0 0,3,34:1:0 0,0,0:0:0 +17 4015 . C 0 . DP=12;I16=8,2,0,0,350,12812,0,0,554,31538,0,0,222,5442,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,222:9:0 0,3,21:1:0 0,0,0:0:0 +17 4016 . C 0 . DP=12;I16=8,3,0,0,350,11956,0,0,614,35138,0,0,247,6109,0,0;QS=2,0;MQSB=0.829029;MQ0F=0 PL:DP:DV 0,30,215:10:0 0,3,32:1:0 0,0,0:0:0 +17 4017 . C 0 . DP=11;I16=5,2,0,0,227,7765,0,0,374,20738,0,0,173,4279,0,0;QS=2,0;MQSB=0.6;MQ0F=0 PL:DP:DV 0,18,161:6:0 0,3,20:1:0 0,0,0:0:0 +17 4018 . G 0 . DP=11;I16=8,2,0,0,284,8442,0,0,554,31538,0,0,249,6201,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,183:9:0 0,3,17:1:0 0,0,0:0:0 +17 4019 . C 0 . DP=11;I16=9,2,0,0,383,14427,0,0,614,35138,0,0,250,6250,0,0;QS=2,0;MQSB=0.777778;MQ0F=0 PL:DP:DV 0,30,228:10:0 0,3,33:1:0 0,0,0:0:0 +17 4020 . T 0 . DP=10;I16=8,2,0,0,362,13668,0,0,554,31538,0,0,250,6250,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,213:9:0 0,3,38:1:0 0,0,0:0:0 +17 4021 . A 0 . DP=10;I16=8,1,0,0,304,10512,0,0,494,27938,0,0,225,5625,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,177:8:0 0,3,33:1:0 0,0,0:0:0 +17 4022 . C 0 . DP=10;I16=7,2,0,0,310,11582,0,0,494,27938,0,0,225,5625,0,0;QS=2,0;MQSB=0.714286;MQ0F=0 PL:DP:DV 0,24,202:8:0 0,3,36:1:0 0,0,0:0:0 +17 4023 . A 0 . DP=10;I16=8,2,0,0,354,13116,0,0,554,31538,0,0,250,6250,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,209:9:0 0,3,40:1:0 0,0,0:0:0 +17 4024 . C 0 . DP=10;I16=8,2,0,0,361,13669,0,0,554,31538,0,0,250,6250,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,214:9:0 0,3,39:1:0 0,0,0:0:0 +17 4025 . T 0 . DP=10;I16=8,1,0,0,360,14488,0,0,494,27938,0,0,224,5576,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,199:8:0 0,3,42:1:0 0,0,0:0:0 +17 4026 . C 0 . DP=10;I16=8,2,0,0,329,11655,0,0,554,31538,0,0,248,6154,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,192:9:0 0,3,39:1:0 0,0,0:0:0 +17 4027 . C 0 . DP=10;I16=8,2,0,0,380,14888,0,0,554,31538,0,0,246,6060,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,231:9:0 0,3,38:1:0 0,0,0:0:0 +17 4028 . T 0 . DP=10;I16=8,2,0,0,333,12157,0,0,554,31538,0,0,244,5970,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,202:9:0 0,3,41:1:0 0,0,0:0:0 +17 4029 . T 0 . DP=10;I16=8,2,0,0,377,14333,0,0,554,31538,0,0,242,5884,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,225:9:0 0,3,38:1:0 0,0,0:0:0 +17 4030 . C 0 . DP=10;I16=8,2,0,0,348,12558,0,0,554,31538,0,0,240,5802,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,211:9:0 0,3,30:1:0 0,0,0:0:0 +17 4031 . T 0 . DP=10;I16=8,2,0,0,388,15302,0,0,554,31538,0,0,238,5724,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,229:9:0 0,3,39:1:0 0,0,0:0:0 +17 4032 . T 0 . DP=10;I16=8,2,0,0,341,11901,0,0,554,31538,0,0,236,5650,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,204:9:0 0,3,39:1:0 0,0,0:0:0 +17 4033 . A 0 . DP=10;I16=7,2,0,0,299,10717,0,0,494,27938,0,0,218,5324,0,0;QS=2,0;MQSB=0.714286;MQ0F=0 PL:DP:DV 0,24,193:8:0 0,3,38:1:0 0,0,0:0:0 +17 4034 . G 0 . DP=10;I16=8,2,0,0,347,12527,0,0,554,31538,0,0,231,5465,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,211:9:0 0,3,39:1:0 0,0,0:0:0 +17 4035 . G T, 0 . DP=10;I16=7,2,1,0,316,11900,13,169,494,27938,60,3600,202,4682,25,625;QS=1.9547,0.0452962,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.75;BQB=1;MQ0F=0 PL:DP:DV 0,13,195,24,198,200:9:1 0,3,31,3,31,31:1:0 0,0,0,0,0,0:0:0 +17 4036 . G 0 . DP=10;I16=8,1,0,0,269,8839,0,0,494,27938,0,0,198,4532,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,156:8:0 0,3,34:1:0 0,0,0:0:0 +17 4037 . C 0 . DP=10;I16=8,2,0,0,342,12466,0,0,554,31538,0,0,219,5015,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,210:9:0 0,3,30:1:0 0,0,0:0:0 +17 4038 . T 0 . DP=10;I16=8,2,0,0,335,12149,0,0,554,31538,0,0,215,4881,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,203:9:0 0,3,29:1:0 0,0,0:0:0 +17 4039 . G 0 . DP=10;I16=8,1,0,0,302,10798,0,0,494,27938,0,0,186,4130,0,0;QS=2,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,180:8:0 0,3,31:1:0 0,0,0:0:0 +17 4040 . A 0 . DP=10;I16=8,2,0,0,380,14602,0,0,554,31538,0,0,207,4637,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,223:9:0 0,3,41:1:0 0,0,0:0:0 +17 4041 . T 0 . DP=10;I16=8,2,0,0,367,13633,0,0,554,31538,0,0,202,4478,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,216:9:0 0,3,40:1:0 0,0,0:0:0 +17 4042 . A 0 . DP=10;I16=8,2,0,0,337,11657,0,0,554,31538,0,0,197,4329,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,205:9:0 0,3,34:1:0 0,0,0:0:0 +17 4043 . T 0 . DP=10;I16=8,2,0,0,314,10428,0,0,554,31538,0,0,192,4190,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,190:9:0 0,3,35:1:0 0,0,0:0:0 +17 4044 . T 0 . DP=10;I16=8,2,0,0,333,11579,0,0,554,31538,0,0,187,4061,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,199:9:0 0,3,37:1:0 0,0,0:0:0 +17 4045 . C 0 . DP=10;I16=7,2,0,0,291,10099,0,0,494,27938,0,0,176,3906,0,0;QS=1,0;MQSB=0.714286;MQ0F=0 PL:DP:DV 0,27,204:9:0 0,0,0:0:0 0,0,0:0:0 +17 4046 . C 0 . DP=10;I16=8,2,0,0,356,13032,0,0,554,31538,0,0,177,3833,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,212:9:0 0,3,35:1:0 0,0,0:0:0 +17 4047 . A 0 . DP=10;I16=8,2,0,0,347,12557,0,0,554,31538,0,0,172,3734,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,204:9:0 0,3,40:1:0 0,0,0:0:0 +17 4048 . C 0 . DP=10;I16=8,2,0,0,342,12124,0,0,554,31538,0,0,167,3645,0,0;QS=2,0;MQSB=0.75;MQ0F=0 PL:DP:DV 0,27,202:9:0 0,3,37:1:0 0,0,0:0:0 +17 4049 . G 0 . DP=10;I16=7,2,0,0,260,7786,0,0,494,27938,0,0,146,3310,0,0;QS=2,0;MQSB=0.714286;MQ0F=0 PL:DP:DV 0,24,173:8:0 0,3,24:1:0 0,0,0:0:0 +17 4050 . C 0 . DP=9;I16=6,2,0,0,291,10813,0,0,434,24338,0,0,157,3495,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL:DP:DV 0,24,204:8:0 0,0,0:0:0 0,0,0:0:0 +17 4051 . A 0 . DP=8;I16=5,2,0,0,259,9679,0,0,374,20738,0,0,146,3370,0,0;QS=1,0;MQSB=0.6;MQ0F=0 PL:DP:DV 0,21,192:7:0 0,0,0:0:0 0,0,0:0:0 +17 4052 . C 0 . DP=8;I16=5,2,0,0,247,9025,0,0,374,20738,0,0,143,3281,0,0;QS=1,0;MQSB=0.6;MQ0F=0 PL:DP:DV 0,21,190:7:0 0,0,0:0:0 0,0,0:0:0 +17 4053 . C 0 . DP=8;I16=6,2,0,0,254,9000,0,0,434,24338,0,0,146,3234,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL:DP:DV 0,24,184:8:0 0,0,0:0:0 0,0,0:0:0 +17 4054 . C 0 . DP=8;I16=3,2,0,0,160,5344,0,0,254,13538,0,0,122,2984,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,134:5:0 0,0,0:0:0 0,0,0:0:0 +17 4055 . G 0 . DP=8;I16=6,2,0,0,230,6982,0,0,434,24338,0,0,138,3066,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL:DP:DV 0,24,169:8:0 0,0,0:0:0 0,0,0:0:0 +17 4056 . C 0 . DP=8;I16=6,2,0,0,275,10153,0,0,434,24338,0,0,134,2994,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL:DP:DV 0,24,197:8:0 0,0,0:0:0 0,0,0:0:0 +17 4057 . T 0 . DP=8;I16=5,2,0,0,243,8603,0,0,374,20738,0,0,127,2877,0,0;QS=1,0;MQSB=0.6;MQ0F=0 PL:DP:DV 0,21,182:7:0 0,0,0:0:0 0,0,0:0:0 +17 4058 . A 0 . DP=7;I16=4,2,0,0,214,7742,0,0,314,17138,0,0,116,2728,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,171:6:0 0,0,0:0:0 0,0,0:0:0 +17 4059 . C 0 . DP=6;I16=4,2,0,0,204,7164,0,0,314,17138,0,0,119,2635,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,168:6:0 0,0,0:0:0 0,0,0:0:0 +17 4060 . A 0 . DP=6;I16=4,2,0,0,227,8683,0,0,314,17138,0,0,115,2501,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,177:6:0 0,0,0:0:0 0,0,0:0:0 +17 4061 . C 0 . DP=6;I16=4,2,0,0,193,6681,0,0,314,17138,0,0,111,2375,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,157:6:0 0,0,0:0:0 0,0,0:0:0 +17 4062 . T 0 . DP=6;I16=4,1,0,0,195,7621,0,0,254,13538,0,0,82,1632,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,151:5:0 0,0,0:0:0 0,0,0:0:0 +17 4063 . C 0 . DP=6;I16=4,2,0,0,216,7984,0,0,314,17138,0,0,102,2098,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,170:6:0 0,0,0:0:0 0,0,0:0:0 +17 4064 . C 0 . DP=6;I16=4,2,0,0,227,8747,0,0,314,17138,0,0,97,1949,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,177:6:0 0,0,0:0:0 0,0,0:0:0 +17 4065 . T 0 . DP=6;I16=4,2,0,0,202,6880,0,0,314,17138,0,0,92,1810,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,161:6:0 0,0,0:0:0 0,0,0:0:0 +17 4066 . T 0 . DP=5;I16=3,2,0,0,180,6554,0,0,254,13538,0,0,88,1680,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,153:5:0 0,0,0:0:0 0,0,0:0:0 +17 4067 . C 0 . DP=5;I16=3,2,0,0,181,6637,0,0,254,13538,0,0,84,1558,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,153:5:0 0,0,0:0:0 0,0,0:0:0 +17 4068 . T 0 . DP=5;I16=3,2,0,0,198,7868,0,0,254,13538,0,0,80,1444,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,164:5:0 0,0,0:0:0 0,0,0:0:0 +17 4069 . T 0 . DP=5;I16=3,2,0,0,177,6325,0,0,254,13538,0,0,76,1338,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,154:5:0 0,0,0:0:0 0,0,0:0:0 +17 4070 . A 0 . DP=5;I16=3,2,0,0,161,5263,0,0,254,13538,0,0,72,1240,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,140:5:0 0,0,0:0:0 0,0,0:0:0 +17 4071 . G 0 . DP=5;I16=3,2,0,0,166,5658,0,0,254,13538,0,0,68,1150,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,142:5:0 0,0,0:0:0 0,0,0:0:0 +17 4072 . G 0 . DP=5;I16=2,2,0,0,138,4974,0,0,194,9938,0,0,55,987,0,0;QS=1,0;MQSB=0;MQ0F=0 PL:DP:DV 0,12,122:4:0 0,0,0:0:0 0,0,0:0:0 +17 4073 . G 0 . DP=5;I16=3,2,0,0,156,5082,0,0,254,13538,0,0,60,994,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,136:5:0 0,0,0:0:0 0,0,0:0:0 +17 4074 . C 0 . DP=5;I16=3,2,0,0,160,5602,0,0,254,13538,0,0,56,928,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,142:5:0 0,0,0:0:0 0,0,0:0:0 +17 4075 . T 0 . DP=5;I16=3,2,0,0,187,7069,0,0,254,13538,0,0,52,870,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,155:5:0 0,0,0:0:0 0,0,0:0:0 +17 4076 . G 0 . DP=5;I16=3,2,0,0,174,6298,0,0,254,13538,0,0,48,820,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL:DP:DV 0,15,149:5:0 0,0,0:0:0 0,0,0:0:0 +17 4077 . A 0 . DP=4;I16=3,1,0,0,138,4810,0,0,194,9938,0,0,44,728,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,12,121:4:0 0,0,0:0:0 0,0,0:0:0 +17 4078 . T 0 . DP=4;I16=3,1,0,0,143,5173,0,0,194,9938,0,0,40,644,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,12,124:4:0 0,0,0:0:0 0,0,0:0:0 +17 4079 . A 0 . DP=4;I16=3,1,0,0,121,3847,0,0,194,9938,0,0,36,568,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,12,107:4:0 0,0,0:0:0 0,0,0:0:0 +17 4080 . T 0 . DP=4;I16=3,0,0,0,106,3778,0,0,134,6338,0,0,25,451,0,0;QS=1,0;MQ0F=0 PL:DP:DV 0,9,87:3:0 0,0,0:0:0 0,0,0:0:0 +17 4081 . T 0 . DP=4;I16=3,1,0,0,106,2934,0,0,194,9938,0,0,28,440,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,12,94:4:0 0,0,0:0:0 0,0,0:0:0 +17 4082 . C 0 . DP=3;I16=2,1,0,0,110,4042,0,0,134,6338,0,0,25,387,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,9,103:3:0 0,0,0:0:0 0,0,0:0:0 +17 4083 . C 0 . DP=3;I16=2,1,0,0,104,3648,0,0,134,6338,0,0,22,340,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,9,98:3:0 0,0,0:0:0 0,0,0:0:0 +17 4084 . A 0 . DP=2;I16=1,1,0,0,78,3050,0,0,97,4969,0,0,20,298,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,6,74:2:0 0,0,0:0:0 0,0,0:0:0 +17 4085 . C 0 . DP=2;I16=1,1,0,0,62,1940,0,0,97,4969,0,0,18,260,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,6,62:2:0 0,0,0:0:0 0,0,0:0:0 +17 4086 . G 0 . DP=2;I16=1,1,0,0,56,1640,0,0,97,4969,0,0,16,226,0,0;QS=1,0;MQSB=1;MQ0F=0 PL:DP:DV 0,6,56:2:0 0,0,0:0:0 0,0,0:0:0 +17 4087 . C 0 . 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C <*> 0 . DP=18;I16=17,0,0,0,688,29762,0,0,958,55682,0,0,332,7446,0,0;QS=3,0;MQ0F=0 PL 0,27,189 0,9,108 0,15,134 +17 101 . C <*> 0 . DP=18;I16=17,0,0,0,650,27530,0,0,958,55682,0,0,331,7303,0,0;QS=3,0;MQ0F=0 PL 0,27,182 0,9,99 0,15,132 +17 102 . C <*> 0 . DP=18;I16=17,0,0,0,695,30453,0,0,958,55682,0,0,330,7178,0,0;QS=3,0;MQ0F=0 PL 0,27,188 0,9,111 0,15,139 +17 103 . T <*> 0 . DP=18;I16=16,0,0,0,692,31998,0,0,929,54841,0,0,323,7035,0,0;QS=3,0;MQ0F=0 PL 0,24,189 0,9,108 0,15,147 +17 104 . G <*> 0 . DP=18;I16=15,0,0,0,611,26723,0,0,900,54000,0,0,295,6259,0,0;QS=3,0;MQ0F=0 PL 0,24,178 0,6,89 0,15,133 +17 105 . G <*> 0 . DP=19;I16=17,0,0,0,604,23936,0,0,989,58441,0,0,317,6751,0,0;QS=3,0;MQ0F=0 PL 0,27,170 0,9,97 0,15,125 +17 106 . G <*> 0 . DP=19;I16=17,0,0,0,644,26574,0,0,989,58441,0,0,299,6093,0,0;QS=3,0;MQ0F=0 PL 0,30,190 0,6,85 0,15,124 +17 107 . C <*> 0 . DP=19;I16=17,0,0,0,694,30064,0,0,989,58441,0,0,313,6543,0,0;QS=3,0;MQ0F=0 PL 0,27,192 0,9,108 0,15,136 +17 108 . C <*> 0 . DP=19;I16=17,0,0,0,692,30148,0,0,989,58441,0,0,310,6420,0,0;QS=3,0;MQ0F=0 PL 0,27,190 0,9,108 0,15,135 +17 109 . T <*> 0 . DP=19;I16=17,0,0,0,741,34273,0,0,989,58441,0,0,307,6319,0,0;QS=3,0;MQ0F=0 PL 0,27,195 0,9,110 0,15,150 +17 110 . G <*> 0 . DP=19;I16=17,0,0,0,704,31276,0,0,989,58441,0,0,304,6240,0,0;QS=3,0;MQ0F=0 PL 0,27,194 0,9,104 0,15,136 +17 111 . G <*> 0 . DP=19;I16=16,0,0,0,584,24362,0,0,929,54841,0,0,272,5416,0,0;QS=3,0;MQ0F=0 PL 0,30,167 0,6,88 0,12,118 +17 112 . C <*> 0 . DP=19;I16=17,0,0,0,680,29854,0,0,989,58441,0,0,296,6052,0,0;QS=3,0;MQ0F=0 PL 0,27,191 0,9,95 0,15,135 +17 113 . A <*> 0 . DP=19;I16=16,0,0,0,645,28035,0,0,960,57600,0,0,266,5318,0,0;QS=3,0;MQ0F=0 PL 0,27,176 0,6,87 0,15,139 +17 114 . C <*> 0 . DP=19;I16=17,0,0,0,674,28788,0,0,989,58441,0,0,286,5856,0,0;QS=3,0;MQ0F=0 PL 0,27,182 0,9,103 0,15,133 +17 115 . C <*> 0 . DP=21;I16=18,0,0,0,708,30546,0,0,1049,62041,0,0,274,5490,0,0;QS=3,0;MQ0F=0 PL 0,30,189 0,6,89 0,18,147 +17 116 . A <*> 0 . DP=21;I16=17,1,0,0,727,31755,0,0,1049,62041,0,0,253,5079,0,0;QS=3,0;MQSB=1;MQ0F=0 PL 0,27,183 0,6,90 0,21,175 +17 117 . G <*> 0 . DP=21;I16=17,1,0,0,712,30478,0,0,1049,62041,0,0,249,5019,0,0;QS=3,0;MQSB=1;MQ0F=0 PL 0,27,183 0,6,85 0,21,177 +17 118 . G <*> 0 . DP=20;I16=16,1,0,0,636,26574,0,0,958,55682,0,0,266,5426,0,0;QS=3,0;MQSB=1;MQ0F=0 PL 0,27,175 0,3,60 0,21,162 +17 119 . G <*> 0 . DP=19;I16=16,1,0,0,629,26439,0,0,958,55682,0,0,267,5553,0,0;QS=3,0;MQSB=1;MQ0F=0 PL 0,24,175 0,6,73 0,21,160 +17 120 . A <*> 0 . DP=19;I16=16,1,0,0,672,29188,0,0,958,55682,0,0,264,5518,0,0;QS=3,0;MQSB=1;MQ0F=0 PL 0,24,175 0,6,83 0,21,171 +17 121 . G <*> 0 . DP=19;I16=16,1,0,0,662,28460,0,0,958,55682,0,0,260,5454,0,0;QS=3,0;MQSB=1;MQ0F=0 PL 0,24,181 0,6,80 0,21,168 +17 122 . C <*> 0 . DP=20;I16=17,1,0,0,716,31224,0,0,1018,59282,0,0,256,5410,0,0;QS=3,0;MQSB=1;MQ0F=0 PL 0,24,181 0,9,99 0,21,178 +17 123 . T <*> 0 . DP=18;I16=15,1,0,0,661,29997,0,0,898,52082,0,0,255,5385,0,0;QS=3,0;MQSB=1;MQ0F=0 PL 0,21,167 0,9,112 0,18,166 +17 124 . T <*> 0 . DP=19;I16=17,1,0,0,626,24802,0,0,987,56523,0,0,279,6003,0,0;QS=3,0;MQSB=1;MQ0F=0 PL 0,27,154 0,9,104 0,18,154 +17 125 . A <*> 0 . DP=18;I16=15,1,0,0,611,25689,0,0,898,52082,0,0,254,5340,0,0;QS=3,0;MQSB=1;MQ0F=0 PL 0,21,154 0,9,104 0,18,162 +17 126 . A <*> 0 . DP=18;I16=16,1,0,0,648,27366,0,0,927,52923,0,0,279,5947,0,0;QS=3,0;MQSB=1;MQ0F=0 PL 0,24,162 0,9,107 0,18,174 +17 127 . C <*> 0 . DP=18;I16=16,1,0,0,646,26972,0,0,927,52923,0,0,279,5949,0,0;QS=3,0;MQSB=1;MQ0F=0 PL 0,24,163 0,9,109 0,18,160 +17 128 . A <*> 0 . DP=18;I16=16,1,0,0,673,28797,0,0,927,52923,0,0,279,5971,0,0;QS=3,0;MQSB=1;MQ0F=0 PL 0,24,169 0,9,111 0,18,162 +17 129 . A <*> 0 . DP=17;I16=15,1,0,0,645,27891,0,0,867,49323,0,0,280,6012,0,0;QS=3,0;MQSB=1;MQ0F=0 PL 0,24,168 0,9,113 0,15,159 +17 130 . A <*> 0 . DP=17;I16=15,1,0,0,641,27295,0,0,867,49323,0,0,281,6071,0,0;QS=3,0;MQSB=1;MQ0F=0 PL 0,24,169 0,9,113 0,15,152 +17 131 . C <*> 0 . DP=16;I16=14,1,0,0,606,25732,0,0,838,48482,0,0,256,5472,0,0;QS=3,0;MQSB=1;MQ0F=0 PL 0,21,167 0,9,110 0,15,147 +17 132 . A <*> 0 . DP=16;I16=14,1,0,0,627,27579,0,0,838,48482,0,0,256,5514,0,0;QS=3,0;MQSB=1;MQ0F=0 PL 0,21,169 0,9,110 0,15,151 +17 133 . T <*> 0 . DP=15;I16=13,2,0,0,584,22816,0,0,838,48482,0,0,282,6196,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL 0,21,163 0,9,105 0,15,150 +17 134 . C <*> 0 . DP=15;I16=13,2,0,0,607,24653,0,0,838,48482,0,0,283,6267,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL 0,21,177 0,9,105 0,15,152 +17 135 . T <*> 0 . DP=15;I16=13,2,0,0,600,24178,0,0,838,48482,0,0,284,6352,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL 0,21,173 0,9,106 0,15,156 +17 136 . G <*> 0 . DP=15;I16=13,2,0,0,574,22258,0,0,838,48482,0,0,286,6450,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL 0,21,172 0,9,105 0,15,134 +17 137 . T <*> 0 . DP=15;I16=13,2,0,0,563,21377,0,0,838,48482,0,0,289,6561,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL 0,21,160 0,9,104 0,15,139 +17 138 . C <*> 0 . DP=15;I16=13,2,0,0,584,23088,0,0,838,48482,0,0,291,6637,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL 0,21,172 0,9,108 0,15,142 +17 139 . C <*> 0 . DP=15;I16=13,2,0,0,554,20790,0,0,838,48482,0,0,292,6680,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL 0,21,161 0,9,106 0,15,143 +17 140 . A <*> 0 . DP=15;I16=13,2,0,0,583,22789,0,0,838,48482,0,0,292,6690,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL 0,21,163 0,9,107 0,15,153 +17 141 . G <*> 0 . DP=14;I16=12,2,0,0,534,20750,0,0,778,44882,0,0,292,6664,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL 0,18,158 0,9,108 0,15,142 +17 142 . C <*> 0 . DP=14;I16=12,2,0,0,503,18593,0,0,778,44882,0,0,292,6650,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL 0,18,157 0,9,97 0,15,129 +17 143 . G <*> 0 . DP=14;I16=11,2,0,0,415,13657,0,0,718,41282,0,0,285,6599,0,0;QS=3,0;MQSB=0.590909;MQ0F=0 PL 0,18,128 0,9,95 0,12,97 +17 144 . A <*> 0 . DP=14;I16=12,2,0,0,519,19725,0,0,778,44882,0,0,291,6609,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL 0,18,152 0,9,105 0,15,129 +17 145 . A <*> 0 . DP=14;I16=12,2,0,0,527,20289,0,0,778,44882,0,0,290,6584,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL 0,18,153 0,9,106 0,15,138 +17 146 . T <*> 0 . DP=14;I16=12,2,0,0,514,19484,0,0,778,44882,0,0,289,6573,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL 0,18,152 0,9,103 0,15,128 +17 147 . A <*> 0 . DP=14;I16=12,2,0,0,515,19213,0,0,778,44882,0,0,288,6576,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL 0,18,150 0,9,99 0,15,140 +17 148 . C <*> 0 . DP=14;I16=12,2,0,0,541,21019,0,0,778,44882,0,0,286,6542,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL 0,18,157 0,9,106 0,15,146 +17 149 . C <*> 0 . DP=14;I16=12,2,0,0,512,19326,0,0,778,44882,0,0,283,6471,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL 0,18,148 0,9,109 0,15,140 +17 150 . T <*> 0 . DP=13;I16=11,2,0,0,511,20251,0,0,749,44041,0,0,280,6362,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL 0,18,153 0,6,84 0,15,152 diff --git a/test/mpileup/mpileup.1.sam b/test/mpileup/mpileup.1.sam new file mode 100644 index 0000000..65d9095 --- /dev/null +++ b/test/mpileup/mpileup.1.sam @@ -0,0 +1,1016 @@ +@HD VN:1.0 SO:coordinate +@SQ SN:17 LN:4200 M5:a9a06ca09c111789d92723fbf39820f6 AS:NCBI37 SP:Human +@RG ID:ERR013140 LB:g1k-sc-HG00100-A SM:HG00100 PI:450 CN:SC PL:ILLUMINA DS:SRP001294 +@RG ID:ERR016352 LB:g1k-sc-HG00100-A SM:HG00100 PI:450 CN:SC PL:ILLUMINA DS:SRP001294 +@RG ID:ERR156632 LB:3815246 SM:HG00100 PI:352 CN:SC PL:ILLUMINA DS:SRP001294 +@RG ID:ERR162872 LB:3815246 SM:HG00100 PI:349 CN:SC PL:ILLUMINA DS:SRP001294 +@RG ID:ERR162875 LB:3815246 SM:HG00100 PI:348 CN:SC PL:ILLUMINA DS:SRP001294 +@RG ID:ERR242939 LB:6503965 SM:HG00100 PI:459 CN:SC PL:ILLUMINA DS:SRP001294 +@RG ID:ERR242943 LB:6503965 SM:HG00100 PI:457 CN:SC PL:ILLUMINA DS:SRP001294 +@RG ID:ERR242947 LB:6503965 SM:HG00100 PI:456 CN:SC PL:ILLUMINA DS:SRP001294 +@RG ID:ERR242951 LB:6503965 SM:HG00100 PI:457 CN:SC PL:ILLUMINA DS:SRP001294 +@RG ID:ERR242955 LB:6503965 SM:HG00100 PI:458 CN:SC PL:ILLUMINA DS:SRP001294 +@RG ID:ERR242959 LB:6503965 SM:HG00100 PI:457 CN:SC PL:ILLUMINA DS:SRP001294 +@RG ID:ERR242963 LB:6503965 SM:HG00100 PI:457 CN:SC PL:ILLUMINA DS:SRP001294 +@RG ID:ERR242967 LB:6503965 SM:HG00100 PI:457 CN:SC PL:ILLUMINA DS:SRP001294 +@RG ID:ERR242971 LB:6503965 SM:HG00100 PI:458 CN:SC PL:ILLUMINA DS:SRP001294 +@RG ID:ERR242975 LB:6503965 SM:HG00100 PI:457 CN:SC PL:ILLUMINA DS:SRP001294 +@RG ID:ERR242979 LB:6503965 SM:HG00100 PI:457 CN:SC PL:ILLUMINA DS:SRP001294 +@RG ID:ERR242983 LB:6503965 SM:HG00100 PI:458 CN:SC PL:ILLUMINA DS:SRP001294 +@RG ID:ERR242987 LB:6503965 SM:HG00100 PI:457 CN:SC PL:ILLUMINA DS:SRP001294 +@RG ID:ERR242991 LB:6503965 SM:HG00100 PI:458 CN:SC PL:ILLUMINA DS:SRP001294 +@RG ID:ERR242995 LB:6503965 SM:HG00100 PI:458 CN:SC PL:ILLUMINA DS:SRP001294 +@RG ID:ERR242999 LB:6503965 SM:HG00100 PI:456 CN:SC PL:ILLUMINA DS:SRP001294 +@RG ID:ERR243003 LB:6503965 SM:HG00100 PI:458 CN:SC PL:ILLUMINA DS:SRP001294 +@RG ID:ERR243007 LB:6503965 SM:HG00100 PI:457 CN:SC PL:ILLUMINA DS:SRP001294 +@RG ID:ERR243011 LB:6503965 SM:HG00100 PI:456 CN:SC PL:ILLUMINA DS:SRP001294 +@RG ID:ERR243015 LB:6503965 SM:HG00100 PI:456 CN:SC PL:ILLUMINA DS:SRP001294 +@RG ID:ERR243019 LB:6503965 SM:HG00100 PI:458 CN:SC PL:ILLUMINA DS:SRP001294 +@RG ID:ERR243023 LB:6503965 SM:HG00100 PI:457 CN:SC PL:ILLUMINA DS:SRP001294 +@RG ID:ERR243027 LB:6503965 SM:HG00100 PI:458 CN:SC PL:ILLUMINA DS:SRP001294 +@RG ID:ERR243031 LB:6503965 SM:HG00100 PI:457 CN:SC PL:ILLUMINA DS:SRP001294 +@RG ID:ERR243035 LB:6503965 SM:HG00100 PI:457 CN:SC PL:ILLUMINA DS:SRP001294 +@RG ID:ERR243039 LB:6503965 SM:HG00100 PI:456 CN:SC PL:ILLUMINA DS:SRP001294 +@RG ID:ERR243043 LB:6503965 SM:HG00100 PI:457 CN:SC PL:ILLUMINA DS:SRP001294 +@RG ID:ERR243047 LB:6503965 SM:HG00100 PI:456 CN:SC PL:ILLUMINA DS:SRP001294 +@RG ID:ERR243051 LB:6503965 SM:HG00100 PI:457 CN:SC PL:ILLUMINA DS:SRP001294 +@RG ID:ERR243055 LB:6503965 SM:HG00100 PI:455 CN:SC PL:ILLUMINA DS:SRP001294 +@RG ID:ERR243059 LB:6503965 SM:HG00100 PI:457 CN:SC PL:ILLUMINA DS:SRP001294 +@RG ID:ERR243063 LB:6503965 SM:HG00100 PI:457 CN:SC PL:ILLUMINA DS:SRP001294 +@RG ID:ERR243067 LB:6503965 SM:HG00100 PI:457 CN:SC PL:ILLUMINA DS:SRP001294 +@RG ID:ERR243071 LB:6503965 SM:HG00100 PI:455 CN:SC PL:ILLUMINA DS:SRP001294 +@RG ID:ERR243075 LB:6503965 SM:HG00100 PI:457 CN:SC PL:ILLUMINA DS:SRP001294 +@RG ID:ERR243079 LB:6503965 SM:HG00100 PI:457 CN:SC PL:ILLUMINA DS:SRP001294 +@RG ID:ERR243083 LB:6503965 SM:HG00100 PI:458 CN:SC PL:ILLUMINA DS:SRP001294 +@RG ID:ERR243087 LB:6503965 SM:HG00100 PI:457 CN:SC PL:ILLUMINA DS:SRP001294 +@RG ID:ERR243091 LB:6503965 SM:HG00100 PI:456 CN:SC PL:ILLUMINA DS:SRP001294 +@RG ID:ERR245024 LB:6503965 SM:HG00100 PI:457 CN:SC PL:ILLUMINA DS:SRP001294 +@RG ID:ERR245028 LB:6503965 SM:HG00100 PI:458 CN:SC PL:ILLUMINA DS:SRP001294 +@RG ID:ERR245032 LB:6503965 SM:HG00100 PI:459 CN:SC PL:ILLUMINA DS:SRP001294 +@RG ID:ERR245034 LB:6503965 SM:HG00100 PI:458 CN:SC PL:ILLUMINA DS:SRP001294 +@RG ID:ERR245038 LB:6503965 SM:HG00100 PI:458 CN:SC PL:ILLUMINA DS:SRP001294 +@RG ID:ERR245041 LB:6503965 SM:HG00100 PI:458 CN:SC PL:ILLUMINA DS:SRP001294 +@RG ID:ERR245045 LB:6503965 SM:HG00100 PI:458 CN:SC PL:ILLUMINA DS:SRP001294 +@RG ID:ERR245049 LB:6503965 SM:HG00100 PI:458 CN:SC PL:ILLUMINA DS:SRP001294 +@RG ID:ERR245053 LB:6503965 SM:HG00100 PI:456 CN:SC PL:ILLUMINA DS:SRP001294 +@PG ID:bwa_index PN:bwa VN:0.5.9-r16 CL:bwa index -a bwtsw $reference_fasta +@PG ID:bwa_aln_fastq PN:bwa PP:bwa_index VN:0.5.9-r16 CL:bwa aln -q 15 -f $sai_file $reference_fasta $fastq_file +@PG ID:bwa_sam PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1350 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) +@PG ID:bwa_sam.1 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1056 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) +@PG ID:bwa_sam.2 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1047 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) +@PG ID:bwa_sam.3 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1044 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) +@PG ID:bwa_sam.4 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1377 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) +@PG ID:bwa_sam.5 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1371 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) +@PG ID:bwa_sam.6 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1368 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) +@PG ID:bwa_sam.7 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1371 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) +@PG ID:bwa_sam.8 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1374 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) +@PG ID:bwa_sam.9 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1371 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) +@PG ID:bwa_sam.10 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1374 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) +@PG ID:bwa_sam.11 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1371 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) +@PG ID:bwa_sam.12 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1374 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) +@PG ID:bwa_sam.13 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1371 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) +@PG ID:bwa_sam.14 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1374 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) +@PG ID:bwa_sam.15 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1368 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) +@PG ID:bwa_sam.16 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1374 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) +@PG ID:bwa_sam.17 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1371 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) +@PG ID:bwa_sam.18 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1368 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) +@PG ID:bwa_sam.19 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1374 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) +@PG ID:bwa_sam.20 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1371 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) +@PG ID:bwa_sam.21 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1374 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) +@PG ID:bwa_sam.22 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1371 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) +@PG ID:bwa_sam.23 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1368 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) +@PG ID:bwa_sam.24 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1371 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) +@PG ID:bwa_sam.25 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1368 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) +@PG ID:bwa_sam.26 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1371 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) +@PG ID:bwa_sam.27 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1365 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) +@PG ID:bwa_sam.28 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1371 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) +@PG ID:bwa_sam.29 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1365 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) +@PG ID:bwa_sam.30 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1371 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) +@PG ID:bwa_sam.31 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1374 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) +@PG ID:bwa_sam.32 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1371 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) +@PG ID:bwa_sam.33 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1368 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) +@PG ID:bwa_sam.34 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1371 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) +@PG ID:bwa_sam.35 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1374 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) +@PG ID:bwa_sam.36 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1377 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) +@PG ID:bwa_sam.37 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1374 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) +@PG ID:bwa_sam.38 PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1368 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) +@PG ID:sam_to_fixed_bam PN:samtools PP:bwa_sam VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file +@PG ID:sam_to_fixed_bam.1 PN:samtools PP:bwa_sam.1 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file +@PG ID:sam_to_fixed_bam.2 PN:samtools PP:bwa_sam.2 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file +@PG ID:sam_to_fixed_bam.3 PN:samtools PP:bwa_sam.3 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file +@PG ID:sam_to_fixed_bam.4 PN:samtools PP:bwa_sam.4 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file +@PG ID:sam_to_fixed_bam.5 PN:samtools PP:bwa_sam.5 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file +@PG ID:sam_to_fixed_bam.6 PN:samtools PP:bwa_sam.6 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file +@PG ID:sam_to_fixed_bam.7 PN:samtools PP:bwa_sam.7 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file +@PG ID:sam_to_fixed_bam.8 PN:samtools PP:bwa_sam.8 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file +@PG ID:sam_to_fixed_bam.9 PN:samtools PP:bwa_sam.9 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file +@PG ID:sam_to_fixed_bam.10 PN:samtools PP:bwa_sam.10 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file +@PG ID:sam_to_fixed_bam.11 PN:samtools PP:bwa_sam.11 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file +@PG ID:sam_to_fixed_bam.12 PN:samtools PP:bwa_sam.12 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file +@PG ID:sam_to_fixed_bam.13 PN:samtools PP:bwa_sam.13 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file +@PG ID:sam_to_fixed_bam.14 PN:samtools PP:bwa_sam.14 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file +@PG ID:sam_to_fixed_bam.15 PN:samtools PP:bwa_sam.15 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file +@PG ID:sam_to_fixed_bam.16 PN:samtools PP:bwa_sam.16 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file +@PG ID:sam_to_fixed_bam.17 PN:samtools PP:bwa_sam.17 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file +@PG ID:sam_to_fixed_bam.18 PN:samtools PP:bwa_sam.18 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file +@PG ID:sam_to_fixed_bam.19 PN:samtools PP:bwa_sam.19 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file +@PG ID:sam_to_fixed_bam.20 PN:samtools PP:bwa_sam.20 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file +@PG ID:sam_to_fixed_bam.21 PN:samtools PP:bwa_sam.21 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file +@PG ID:sam_to_fixed_bam.22 PN:samtools PP:bwa_sam.22 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file +@PG ID:sam_to_fixed_bam.23 PN:samtools PP:bwa_sam.23 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file +@PG ID:sam_to_fixed_bam.24 PN:samtools PP:bwa_sam.24 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file +@PG ID:sam_to_fixed_bam.25 PN:samtools PP:bwa_sam.25 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file +@PG ID:sam_to_fixed_bam.26 PN:samtools PP:bwa_sam.26 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file +@PG ID:sam_to_fixed_bam.27 PN:samtools PP:bwa_sam.27 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file +@PG ID:sam_to_fixed_bam.28 PN:samtools PP:bwa_sam.28 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file +@PG ID:sam_to_fixed_bam.29 PN:samtools PP:bwa_sam.29 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file +@PG ID:sam_to_fixed_bam.30 PN:samtools PP:bwa_sam.30 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file +@PG ID:sam_to_fixed_bam.31 PN:samtools PP:bwa_sam.31 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file +@PG ID:sam_to_fixed_bam.32 PN:samtools PP:bwa_sam.32 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file +@PG ID:sam_to_fixed_bam.33 PN:samtools PP:bwa_sam.33 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file +@PG ID:sam_to_fixed_bam.34 PN:samtools PP:bwa_sam.34 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file +@PG ID:sam_to_fixed_bam.35 PN:samtools PP:bwa_sam.35 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file +@PG ID:sam_to_fixed_bam.36 PN:samtools PP:bwa_sam.36 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file +@PG ID:sam_to_fixed_bam.37 PN:samtools PP:bwa_sam.37 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file +@PG ID:sam_to_fixed_bam.38 PN:samtools PP:bwa_sam.38 VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file +@PG ID:gatk_target_interval_creator PN:GenomeAnalysisTK PP:sam_to_fixed_bam VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) +@PG ID:gatk_target_interval_creator.1 PN:GenomeAnalysisTK PP:sam_to_fixed_bam.1 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) +@PG ID:gatk_target_interval_creator.2 PN:GenomeAnalysisTK PP:sam_to_fixed_bam.2 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) +@PG ID:gatk_target_interval_creator.3 PN:GenomeAnalysisTK PP:sam_to_fixed_bam.3 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) +@PG ID:gatk_target_interval_creator.4 PN:GenomeAnalysisTK PP:sam_to_fixed_bam.4 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) +@PG ID:gatk_target_interval_creator.5 PN:GenomeAnalysisTK PP:sam_to_fixed_bam.5 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) +@PG ID:gatk_target_interval_creator.6 PN:GenomeAnalysisTK PP:sam_to_fixed_bam.6 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) +@PG ID:gatk_target_interval_creator.7 PN:GenomeAnalysisTK PP:sam_to_fixed_bam.7 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) +@PG ID:gatk_target_interval_creator.8 PN:GenomeAnalysisTK PP:sam_to_fixed_bam.8 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) +@PG ID:gatk_target_interval_creator.9 PN:GenomeAnalysisTK PP:sam_to_fixed_bam.9 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) +@PG ID:gatk_target_interval_creator.10 PN:GenomeAnalysisTK PP:sam_to_fixed_bam.10 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) +@PG ID:gatk_target_interval_creator.11 PN:GenomeAnalysisTK PP:sam_to_fixed_bam.11 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) +@PG ID:gatk_target_interval_creator.12 PN:GenomeAnalysisTK PP:sam_to_fixed_bam.12 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) +@PG 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PN:GenomeAnalysisTK PP:sam_to_fixed_bam.17 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) +@PG ID:gatk_target_interval_creator.18 PN:GenomeAnalysisTK PP:sam_to_fixed_bam.18 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) +@PG ID:gatk_target_interval_creator.19 PN:GenomeAnalysisTK PP:sam_to_fixed_bam.19 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) +@PG ID:gatk_target_interval_creator.20 PN:GenomeAnalysisTK PP:sam_to_fixed_bam.20 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) +@PG ID:gatk_target_interval_creator.21 PN:GenomeAnalysisTK 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VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) +@PG ID:gatk_target_interval_creator.26 PN:GenomeAnalysisTK PP:sam_to_fixed_bam.26 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) +@PG ID:gatk_target_interval_creator.27 PN:GenomeAnalysisTK PP:sam_to_fixed_bam.27 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) +@PG ID:gatk_target_interval_creator.28 PN:GenomeAnalysisTK PP:sam_to_fixed_bam.28 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) +@PG ID:gatk_target_interval_creator.29 PN:GenomeAnalysisTK PP:sam_to_fixed_bam.29 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) +@PG ID:gatk_target_interval_creator.30 PN:GenomeAnalysisTK PP:sam_to_fixed_bam.30 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) +@PG ID:gatk_target_interval_creator.31 PN:GenomeAnalysisTK PP:sam_to_fixed_bam.31 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) +@PG ID:gatk_target_interval_creator.32 PN:GenomeAnalysisTK PP:sam_to_fixed_bam.32 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) +@PG ID:gatk_target_interval_creator.33 PN:GenomeAnalysisTK PP:sam_to_fixed_bam.33 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) +@PG ID:gatk_target_interval_creator.34 PN:GenomeAnalysisTK PP:sam_to_fixed_bam.34 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) +@PG ID:gatk_target_interval_creator.35 PN:GenomeAnalysisTK PP:sam_to_fixed_bam.35 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) +@PG ID:gatk_target_interval_creator.36 PN:GenomeAnalysisTK PP:sam_to_fixed_bam.36 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) +@PG ID:gatk_target_interval_creator.37 PN:GenomeAnalysisTK PP:sam_to_fixed_bam.37 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) +@PG ID:gatk_target_interval_creator.38 PN:GenomeAnalysisTK PP:sam_to_fixed_bam.38 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) +@PG ID:bam_realignment_around_known_indels PN:GenomeAnalysisTK PP:gatk_target_interval_creator VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing +@PG ID:bam_realignment_around_known_indels.1 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.1 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing +@PG ID:bam_realignment_around_known_indels.2 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.2 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing +@PG ID:bam_realignment_around_known_indels.3 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.3 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing +@PG ID:bam_realignment_around_known_indels.4 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.4 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing +@PG ID:bam_realignment_around_known_indels.5 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.5 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing +@PG ID:bam_realignment_around_known_indels.6 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.6 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing +@PG ID:bam_realignment_around_known_indels.7 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.7 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing +@PG ID:bam_realignment_around_known_indels.8 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.8 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing +@PG ID:bam_realignment_around_known_indels.9 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.9 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing +@PG ID:bam_realignment_around_known_indels.10 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.10 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing +@PG ID:bam_realignment_around_known_indels.11 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.11 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing +@PG ID:bam_realignment_around_known_indels.12 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.12 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing +@PG ID:bam_realignment_around_known_indels.13 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.13 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing +@PG ID:bam_realignment_around_known_indels.14 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.14 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing +@PG ID:bam_realignment_around_known_indels.15 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.15 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing +@PG ID:bam_realignment_around_known_indels.16 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.16 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing +@PG ID:bam_realignment_around_known_indels.17 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.17 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing +@PG ID:bam_realignment_around_known_indels.18 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.18 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing +@PG ID:bam_realignment_around_known_indels.19 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.19 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing +@PG ID:bam_realignment_around_known_indels.20 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.20 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing +@PG ID:bam_realignment_around_known_indels.21 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.21 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing +@PG ID:bam_realignment_around_known_indels.22 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.22 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing +@PG ID:bam_realignment_around_known_indels.23 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.23 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing +@PG ID:bam_realignment_around_known_indels.24 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.24 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing +@PG ID:bam_realignment_around_known_indels.25 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.25 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing +@PG ID:bam_realignment_around_known_indels.26 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.26 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing +@PG ID:bam_realignment_around_known_indels.27 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.27 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing +@PG ID:bam_realignment_around_known_indels.28 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.28 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing +@PG ID:bam_realignment_around_known_indels.29 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.29 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing +@PG ID:bam_realignment_around_known_indels.30 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.30 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing +@PG ID:bam_realignment_around_known_indels.31 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.31 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing +@PG ID:bam_realignment_around_known_indels.32 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.32 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing +@PG ID:bam_realignment_around_known_indels.33 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.33 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing +@PG ID:bam_realignment_around_known_indels.34 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.34 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing +@PG ID:bam_realignment_around_known_indels.35 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.35 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing +@PG ID:bam_realignment_around_known_indels.36 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.36 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing +@PG ID:bam_realignment_around_known_indels.37 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.37 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing +@PG ID:bam_realignment_around_known_indels.38 PN:GenomeAnalysisTK PP:gatk_target_interval_creator.38 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing +@PG ID:bam_count_covariates PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate +@PG ID:bam_count_covariates.1 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.1 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate +@PG ID:bam_count_covariates.2 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.2 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate +@PG ID:bam_count_covariates.3 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.3 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate +@PG ID:bam_count_covariates.4 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.4 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate +@PG ID:bam_count_covariates.5 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.5 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate +@PG ID:bam_count_covariates.6 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.6 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate +@PG ID:bam_count_covariates.7 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.7 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate +@PG ID:bam_count_covariates.8 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.8 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate +@PG ID:bam_count_covariates.9 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.9 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate +@PG ID:bam_count_covariates.10 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.10 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate +@PG ID:bam_count_covariates.11 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.11 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate +@PG ID:bam_count_covariates.12 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.12 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate +@PG ID:bam_count_covariates.13 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.13 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate +@PG ID:bam_count_covariates.14 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.14 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate +@PG ID:bam_count_covariates.15 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.15 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate +@PG ID:bam_count_covariates.16 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.16 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate +@PG ID:bam_count_covariates.17 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.17 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate +@PG ID:bam_count_covariates.18 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.18 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate +@PG ID:bam_count_covariates.19 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.19 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate +@PG ID:bam_count_covariates.20 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.20 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate +@PG ID:bam_count_covariates.21 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.21 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate +@PG ID:bam_count_covariates.22 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.22 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate +@PG ID:bam_count_covariates.23 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.23 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate +@PG ID:bam_count_covariates.24 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.24 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate +@PG ID:bam_count_covariates.25 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.25 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate +@PG ID:bam_count_covariates.26 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.26 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate +@PG ID:bam_count_covariates.27 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.27 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate +@PG ID:bam_count_covariates.28 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.28 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate +@PG ID:bam_count_covariates.29 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.29 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate +@PG ID:bam_count_covariates.30 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.30 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate +@PG ID:bam_count_covariates.31 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.31 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate +@PG ID:bam_count_covariates.32 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.32 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate +@PG ID:bam_count_covariates.33 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.33 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate +@PG ID:bam_count_covariates.34 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.34 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate +@PG ID:bam_count_covariates.35 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.35 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate +@PG ID:bam_count_covariates.36 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.36 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate +@PG ID:bam_count_covariates.37 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.37 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate +@PG ID:bam_count_covariates.38 PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels.38 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate +@PG ID:bam_recalibrate_quality_scores PN:GenomeAnalysisTK PP:bam_count_covariates VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing +@PG ID:bam_recalibrate_quality_scores.1 PN:GenomeAnalysisTK PP:bam_count_covariates.1 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing +@PG ID:bam_recalibrate_quality_scores.2 PN:GenomeAnalysisTK PP:bam_count_covariates.2 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing +@PG ID:bam_recalibrate_quality_scores.3 PN:GenomeAnalysisTK PP:bam_count_covariates.3 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing +@PG ID:bam_recalibrate_quality_scores.4 PN:GenomeAnalysisTK PP:bam_count_covariates.4 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing +@PG ID:bam_recalibrate_quality_scores.5 PN:GenomeAnalysisTK PP:bam_count_covariates.5 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing +@PG ID:bam_recalibrate_quality_scores.6 PN:GenomeAnalysisTK PP:bam_count_covariates.6 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing +@PG ID:bam_recalibrate_quality_scores.7 PN:GenomeAnalysisTK PP:bam_count_covariates.7 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing +@PG ID:bam_recalibrate_quality_scores.8 PN:GenomeAnalysisTK PP:bam_count_covariates.8 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing +@PG ID:bam_recalibrate_quality_scores.9 PN:GenomeAnalysisTK PP:bam_count_covariates.9 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing +@PG ID:bam_recalibrate_quality_scores.10 PN:GenomeAnalysisTK PP:bam_count_covariates.10 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing +@PG ID:bam_recalibrate_quality_scores.11 PN:GenomeAnalysisTK PP:bam_count_covariates.11 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing +@PG ID:bam_recalibrate_quality_scores.12 PN:GenomeAnalysisTK PP:bam_count_covariates.12 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing +@PG ID:bam_recalibrate_quality_scores.13 PN:GenomeAnalysisTK PP:bam_count_covariates.13 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing +@PG ID:bam_recalibrate_quality_scores.14 PN:GenomeAnalysisTK PP:bam_count_covariates.14 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing +@PG ID:bam_recalibrate_quality_scores.15 PN:GenomeAnalysisTK PP:bam_count_covariates.15 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing +@PG ID:bam_recalibrate_quality_scores.16 PN:GenomeAnalysisTK PP:bam_count_covariates.16 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing +@PG ID:bam_recalibrate_quality_scores.17 PN:GenomeAnalysisTK PP:bam_count_covariates.17 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing +@PG ID:bam_recalibrate_quality_scores.18 PN:GenomeAnalysisTK PP:bam_count_covariates.18 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing +@PG ID:bam_recalibrate_quality_scores.19 PN:GenomeAnalysisTK PP:bam_count_covariates.19 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing +@PG ID:bam_recalibrate_quality_scores.20 PN:GenomeAnalysisTK PP:bam_count_covariates.20 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing +@PG ID:bam_recalibrate_quality_scores.21 PN:GenomeAnalysisTK PP:bam_count_covariates.21 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing +@PG ID:bam_recalibrate_quality_scores.22 PN:GenomeAnalysisTK PP:bam_count_covariates.22 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing +@PG ID:bam_recalibrate_quality_scores.23 PN:GenomeAnalysisTK PP:bam_count_covariates.23 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing +@PG ID:bam_recalibrate_quality_scores.24 PN:GenomeAnalysisTK PP:bam_count_covariates.24 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing +@PG ID:bam_recalibrate_quality_scores.25 PN:GenomeAnalysisTK PP:bam_count_covariates.25 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing +@PG ID:bam_recalibrate_quality_scores.26 PN:GenomeAnalysisTK PP:bam_count_covariates.26 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing +@PG ID:bam_recalibrate_quality_scores.27 PN:GenomeAnalysisTK PP:bam_count_covariates.27 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing +@PG ID:bam_recalibrate_quality_scores.28 PN:GenomeAnalysisTK PP:bam_count_covariates.28 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing +@PG ID:bam_recalibrate_quality_scores.29 PN:GenomeAnalysisTK PP:bam_count_covariates.29 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing +@PG ID:bam_recalibrate_quality_scores.30 PN:GenomeAnalysisTK PP:bam_count_covariates.30 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing +@PG ID:bam_recalibrate_quality_scores.31 PN:GenomeAnalysisTK PP:bam_count_covariates.31 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing +@PG ID:bam_recalibrate_quality_scores.32 PN:GenomeAnalysisTK PP:bam_count_covariates.32 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing +@PG ID:bam_recalibrate_quality_scores.33 PN:GenomeAnalysisTK PP:bam_count_covariates.33 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing +@PG ID:bam_recalibrate_quality_scores.34 PN:GenomeAnalysisTK PP:bam_count_covariates.34 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing +@PG ID:bam_recalibrate_quality_scores.35 PN:GenomeAnalysisTK PP:bam_count_covariates.35 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing +@PG ID:bam_recalibrate_quality_scores.36 PN:GenomeAnalysisTK PP:bam_count_covariates.36 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing +@PG ID:bam_recalibrate_quality_scores.37 PN:GenomeAnalysisTK PP:bam_count_covariates.37 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing +@PG ID:bam_recalibrate_quality_scores.38 PN:GenomeAnalysisTK PP:bam_count_covariates.38 VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing +@PG ID:bam_calculate_bq PN:samtools PP:bam_recalibrate_quality_scores VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file +@PG ID:bam_calculate_bq.1 PN:samtools PP:bam_recalibrate_quality_scores.1 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file +@PG ID:bam_calculate_bq.2 PN:samtools PP:bam_recalibrate_quality_scores.2 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file +@PG ID:bam_calculate_bq.3 PN:samtools PP:bam_recalibrate_quality_scores.3 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file +@PG ID:bam_calculate_bq.4 PN:samtools PP:bam_recalibrate_quality_scores.4 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file +@PG ID:bam_calculate_bq.5 PN:samtools PP:bam_recalibrate_quality_scores.5 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file +@PG ID:bam_calculate_bq.6 PN:samtools PP:bam_recalibrate_quality_scores.6 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file +@PG ID:bam_calculate_bq.7 PN:samtools PP:bam_recalibrate_quality_scores.7 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file +@PG ID:bam_calculate_bq.8 PN:samtools PP:bam_recalibrate_quality_scores.8 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file +@PG ID:bam_calculate_bq.9 PN:samtools PP:bam_recalibrate_quality_scores.9 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file +@PG ID:bam_calculate_bq.10 PN:samtools PP:bam_recalibrate_quality_scores.10 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file +@PG ID:bam_calculate_bq.11 PN:samtools PP:bam_recalibrate_quality_scores.11 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file +@PG ID:bam_calculate_bq.12 PN:samtools PP:bam_recalibrate_quality_scores.12 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file +@PG ID:bam_calculate_bq.13 PN:samtools PP:bam_recalibrate_quality_scores.13 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file +@PG ID:bam_calculate_bq.14 PN:samtools PP:bam_recalibrate_quality_scores.14 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file +@PG ID:bam_calculate_bq.15 PN:samtools PP:bam_recalibrate_quality_scores.15 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file +@PG ID:bam_calculate_bq.16 PN:samtools PP:bam_recalibrate_quality_scores.16 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file +@PG ID:bam_calculate_bq.17 PN:samtools PP:bam_recalibrate_quality_scores.17 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file +@PG ID:bam_calculate_bq.18 PN:samtools PP:bam_recalibrate_quality_scores.18 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file +@PG ID:bam_calculate_bq.19 PN:samtools PP:bam_recalibrate_quality_scores.19 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file +@PG ID:bam_calculate_bq.20 PN:samtools PP:bam_recalibrate_quality_scores.20 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file +@PG ID:bam_calculate_bq.21 PN:samtools PP:bam_recalibrate_quality_scores.21 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file +@PG ID:bam_calculate_bq.22 PN:samtools PP:bam_recalibrate_quality_scores.22 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file +@PG ID:bam_calculate_bq.23 PN:samtools PP:bam_recalibrate_quality_scores.23 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file +@PG ID:bam_calculate_bq.24 PN:samtools PP:bam_recalibrate_quality_scores.24 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file +@PG ID:bam_calculate_bq.25 PN:samtools PP:bam_recalibrate_quality_scores.25 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file +@PG ID:bam_calculate_bq.26 PN:samtools PP:bam_recalibrate_quality_scores.26 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file +@PG ID:bam_calculate_bq.27 PN:samtools PP:bam_recalibrate_quality_scores.27 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file +@PG ID:bam_calculate_bq.28 PN:samtools PP:bam_recalibrate_quality_scores.28 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file +@PG ID:bam_calculate_bq.29 PN:samtools PP:bam_recalibrate_quality_scores.29 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file +@PG ID:bam_calculate_bq.30 PN:samtools PP:bam_recalibrate_quality_scores.30 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file +@PG ID:bam_calculate_bq.31 PN:samtools PP:bam_recalibrate_quality_scores.31 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file +@PG ID:bam_calculate_bq.32 PN:samtools PP:bam_recalibrate_quality_scores.32 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file +@PG ID:bam_calculate_bq.33 PN:samtools PP:bam_recalibrate_quality_scores.33 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file +@PG ID:bam_calculate_bq.34 PN:samtools PP:bam_recalibrate_quality_scores.34 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file +@PG ID:bam_calculate_bq.35 PN:samtools PP:bam_recalibrate_quality_scores.35 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file +@PG ID:bam_calculate_bq.36 PN:samtools PP:bam_recalibrate_quality_scores.36 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file +@PG ID:bam_calculate_bq.37 PN:samtools PP:bam_recalibrate_quality_scores.37 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file +@PG ID:bam_calculate_bq.38 PN:samtools PP:bam_recalibrate_quality_scores.38 VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file +@PG ID:bam_merge PN:picard PP:bam_calculate_bq VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.1 PN:picard PP:bam_calculate_bq.1 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.2 PN:picard PP:bam_calculate_bq.2 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.3 PN:picard PP:bam_calculate_bq.3 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.4 PN:picard PP:bam_calculate_bq.4 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.5 PN:picard PP:bam_calculate_bq.5 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.6 PN:picard PP:bam_calculate_bq.6 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.7 PN:picard PP:bam_calculate_bq.7 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.8 PN:picard PP:bam_calculate_bq.8 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.9 PN:picard PP:bam_calculate_bq.9 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.10 PN:picard PP:bam_calculate_bq.10 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.11 PN:picard PP:bam_calculate_bq.11 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.12 PN:picard PP:bam_calculate_bq.12 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.13 PN:picard PP:bam_calculate_bq.13 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.14 PN:picard PP:bam_calculate_bq.14 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.15 PN:picard PP:bam_calculate_bq.15 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.16 PN:picard PP:bam_calculate_bq.16 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.17 PN:picard PP:bam_calculate_bq.17 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.18 PN:picard PP:bam_calculate_bq.18 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.19 PN:picard PP:bam_calculate_bq.19 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.20 PN:picard PP:bam_calculate_bq.20 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.21 PN:picard PP:bam_calculate_bq.21 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.22 PN:picard PP:bam_calculate_bq.22 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.23 PN:picard PP:bam_calculate_bq.23 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.24 PN:picard PP:bam_calculate_bq.24 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.25 PN:picard PP:bam_calculate_bq.25 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.26 PN:picard PP:bam_calculate_bq.26 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.27 PN:picard PP:bam_calculate_bq.27 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.28 PN:picard PP:bam_calculate_bq.28 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.29 PN:picard PP:bam_calculate_bq.29 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.30 PN:picard PP:bam_calculate_bq.30 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.31 PN:picard PP:bam_calculate_bq.31 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.32 PN:picard PP:bam_calculate_bq.32 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.33 PN:picard PP:bam_calculate_bq.33 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.34 PN:picard PP:bam_calculate_bq.34 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.35 PN:picard PP:bam_calculate_bq.35 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.36 PN:picard PP:bam_calculate_bq.36 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.37 PN:picard PP:bam_calculate_bq.37 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.38 PN:picard PP:bam_calculate_bq.38 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_mark_duplicates PN:picard PP:bam_merge VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT +@PG ID:bam_mark_duplicates.1 PN:picard PP:bam_merge.1 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT +@PG ID:bam_mark_duplicates.2 PN:picard PP:bam_merge.2 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT +@PG ID:bam_mark_duplicates.3 PN:picard PP:bam_merge.3 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT +@PG ID:bam_mark_duplicates.4 PN:picard PP:bam_merge.4 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT +@PG ID:bam_mark_duplicates.5 PN:picard PP:bam_merge.5 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT +@PG ID:bam_mark_duplicates.6 PN:picard PP:bam_merge.6 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT +@PG ID:bam_mark_duplicates.7 PN:picard PP:bam_merge.7 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT +@PG ID:bam_mark_duplicates.8 PN:picard PP:bam_merge.8 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT +@PG ID:bam_mark_duplicates.9 PN:picard PP:bam_merge.9 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT +@PG ID:bam_mark_duplicates.10 PN:picard PP:bam_merge.10 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT +@PG ID:bam_mark_duplicates.11 PN:picard PP:bam_merge.11 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT +@PG ID:bam_mark_duplicates.12 PN:picard PP:bam_merge.12 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT +@PG ID:bam_mark_duplicates.13 PN:picard PP:bam_merge.13 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT +@PG ID:bam_mark_duplicates.14 PN:picard PP:bam_merge.14 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT +@PG ID:bam_mark_duplicates.15 PN:picard PP:bam_merge.15 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT +@PG ID:bam_mark_duplicates.16 PN:picard PP:bam_merge.16 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT +@PG ID:bam_mark_duplicates.17 PN:picard PP:bam_merge.17 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT +@PG ID:bam_mark_duplicates.18 PN:picard PP:bam_merge.18 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT +@PG ID:bam_mark_duplicates.19 PN:picard PP:bam_merge.19 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT +@PG ID:bam_mark_duplicates.20 PN:picard PP:bam_merge.20 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT +@PG ID:bam_mark_duplicates.21 PN:picard PP:bam_merge.21 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT +@PG ID:bam_mark_duplicates.22 PN:picard PP:bam_merge.22 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT +@PG ID:bam_mark_duplicates.23 PN:picard PP:bam_merge.23 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT +@PG ID:bam_mark_duplicates.24 PN:picard PP:bam_merge.24 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT +@PG ID:bam_mark_duplicates.25 PN:picard PP:bam_merge.25 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT +@PG ID:bam_mark_duplicates.26 PN:picard PP:bam_merge.26 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT +@PG ID:bam_mark_duplicates.27 PN:picard PP:bam_merge.27 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT +@PG ID:bam_mark_duplicates.28 PN:picard PP:bam_merge.28 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT +@PG ID:bam_mark_duplicates.29 PN:picard PP:bam_merge.29 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT +@PG ID:bam_mark_duplicates.30 PN:picard PP:bam_merge.30 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT +@PG ID:bam_mark_duplicates.31 PN:picard PP:bam_merge.31 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT +@PG ID:bam_mark_duplicates.32 PN:picard PP:bam_merge.32 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT +@PG ID:bam_mark_duplicates.33 PN:picard PP:bam_merge.33 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT +@PG ID:bam_mark_duplicates.34 PN:picard PP:bam_merge.34 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT +@PG ID:bam_mark_duplicates.35 PN:picard PP:bam_merge.35 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT +@PG ID:bam_mark_duplicates.36 PN:picard PP:bam_merge.36 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT +@PG ID:bam_mark_duplicates.37 PN:picard PP:bam_merge.37 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT +@PG ID:bam_mark_duplicates.38 PN:picard PP:bam_merge.38 VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.39 PN:picard PP:bam_mark_duplicates VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.1.39 PN:picard PP:bam_mark_duplicates.1 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.2.39 PN:picard PP:bam_mark_duplicates.2 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.3.39 PN:picard PP:bam_mark_duplicates.3 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.4.39 PN:picard PP:bam_mark_duplicates.4 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.5.39 PN:picard PP:bam_mark_duplicates.5 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.6.39 PN:picard PP:bam_mark_duplicates.6 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.7.39 PN:picard PP:bam_mark_duplicates.7 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.8.39 PN:picard PP:bam_mark_duplicates.8 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.9.39 PN:picard PP:bam_mark_duplicates.9 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.10.39 PN:picard PP:bam_mark_duplicates.10 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.11.39 PN:picard PP:bam_mark_duplicates.11 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.12.39 PN:picard PP:bam_mark_duplicates.12 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.13.39 PN:picard PP:bam_mark_duplicates.13 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.14.39 PN:picard PP:bam_mark_duplicates.14 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.15.39 PN:picard PP:bam_mark_duplicates.15 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.16.39 PN:picard PP:bam_mark_duplicates.16 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.17.39 PN:picard PP:bam_mark_duplicates.17 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.18.39 PN:picard PP:bam_mark_duplicates.18 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.19.39 PN:picard PP:bam_mark_duplicates.19 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.20.39 PN:picard PP:bam_mark_duplicates.20 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.21.39 PN:picard PP:bam_mark_duplicates.21 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.22.39 PN:picard PP:bam_mark_duplicates.22 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.23.39 PN:picard PP:bam_mark_duplicates.23 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.24.39 PN:picard PP:bam_mark_duplicates.24 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.25.39 PN:picard PP:bam_mark_duplicates.25 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.26.39 PN:picard PP:bam_mark_duplicates.26 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.27.39 PN:picard PP:bam_mark_duplicates.27 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.28.39 PN:picard PP:bam_mark_duplicates.28 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.29.39 PN:picard PP:bam_mark_duplicates.29 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.30.39 PN:picard PP:bam_mark_duplicates.30 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.31.39 PN:picard PP:bam_mark_duplicates.31 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.32.39 PN:picard PP:bam_mark_duplicates.32 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.33.39 PN:picard PP:bam_mark_duplicates.33 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.34.39 PN:picard PP:bam_mark_duplicates.34 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.35.39 PN:picard PP:bam_mark_duplicates.35 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.36.39 PN:picard PP:bam_mark_duplicates.36 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.37.39 PN:picard PP:bam_mark_duplicates.37 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.38.39 PN:picard PP:bam_mark_duplicates.38 VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +ERR013140.3521432 99 17 1 29 22S86M = 226 313 AGAGGTCCCCAACTTCTTTGCAAAGCTTCTCACCCTGTTCCTGCATAGATAATTGCATGACAATTGCCTTGTCCCTGCTGAATGTGCTCTGGGGTCTCTGGGGTCTCA @AEDGBHIIIIIFJGIKHGHIJJJEJKHJKJKGKLLIFHKLLCJJIDEFFHKHEHHJIIIDJEEEJEIKGJIHCGKHFKFE9BBDIAJAHF4?DE@I:DD48(86D=> MD:Z:86 RG:Z:ERR013140 AM:i:29 NM:i:0 SM:i:29 MQ:i:29 XT:A:M BQ:Z:@@@@@@@@@@@@@@@@@@@@@@iidijgijijfjkkhegjkkbiihcdeegjgdggihhhcidddidhjfihgbfjgejedXaach`i`geS^cd_hYccSWGWUc\] +ERR156632.12704932 163 17 1 29 36S64M = 195 293 TGGAGAAGGGGACAAGAGGTCCCCAACTTCTTTGCAAAGCTTCTCACCCTGTTCCTGCATAGATAATTGCATGACAATTGCCTTGTCCCTGCTGAATGTG BFAFGFEIGFEFHHEIDKJGHHHJIIE=@KKGGKJGIBLLMFKMDIIHJKKHFELLLKFIHMHIHHIHLKJFCHFJIJAID=JHKFGHJIHKKCH:@HD? MD:Z:64 RG:Z:ERR156632 AM:i:29 NM:i:0 SM:i:29 MQ:i:29 XT:A:M BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@hakklejlchhgijjgedkkkjehglghgghgkjiebgeihi`hc\igjefgihgjjbgY_gc^ +ERR156632.9601178 99 17 1 29 62S38M = 279 377 CTATGACAGGGAGGTCATGTGCAGGCTGGAGAAGGGGACAAGAGGTCCCCAACTTCTTTGCAAAGCTTCTCACCCTGTTCCTGCATAGATAATTGCATGA DEEEIIHHKIJILKHLHIKEKHHMKLKKJGKKKKLKLFIHEKIKL=KLJLKIILHKMH9LJJJJLHLHJJKJJKMLKJD>MJKLEHIGHIH=FFCHF>BE MD:Z:38 RG:Z:ERR156632 AM:i:29 NM:i:0 SM:i:29 MQ:i:29 XT:A:M BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@iikgkgiijiijlkjic]lijkdghfghg\eebge]ad +ERR162872.21706338 99 17 1 29 10S90M = 246 344 CTTCTTTGCAAAGCTTCTCACCCTGTTCCTGCATAGATAATTGCATGACAATTGCCTTGTCCCTGCTGAATGTGCTCTGGGGTCTCTGGGGTCTCACCCA BHBFHDKHGHJFJIFIDFDIJHHJHHIICKKKIJIHH?JJKEKGHGJCGGEHFIHJHFK;HGIHIJGICIEDH X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243011 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@J +ERR162875.9416595 163 17 23 60 100M = 239 314 ATAGATAATTGCATGACAATTGCCTTGTCCCTGCTGAATGTGCTCTGGGGTCTCTGGGGTCTCACCCACGACCAACTCCCTGGGCCTGGCACCAGGGAGC DBDIGHGHIBKJIIKIJJGJGKKIKILIKKLJLLKKJJILIJJLMKKIJJHIKLLKJKHDELMJHFKIKDKDKIHHILFKLHBMKGLJ7KGDJHBBFFGD X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162875.23732910 163 17 25 60 100M = 299 373 AGATAATTGCATGACAATTGCCTTGTCCCTGCTGAATGTGCTCTGGGGTCTCTGGGGTCTCACCCACGACCAACTCCCTGGGCCTGGCACCAGGGAGCTT DFEEGGHGJDIHKJIIHHHLKKLHIILLKKMILLKHKMIMMLJLLKLIGJFIKMJJKEMMLHKGDIJ?CILGIIJJLKLL6KMKLM7IIGJGJF?CFEG? X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:25 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B@ +ERR162872.5127873 113 17 28 37 100M * 0 0 TAATTGCATGACAATTGCCTTGTCCCTGCTGAATGTGCTCTGGGGTCTCTGGGGTCTCACCCACGACCAACTCCCTGGGCCTGGCACCAGGGAGCTTAAC .BDEFHG?AEFGHIFCEHLGIIFJIA@LCFKAFJDJDEIBHELKIJMH8FJJKHAMG>GHGKHAKFKHHGGEL=LIJJIILCJHJGHJIHEFIFI9DBGB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162872.19056012 113 17 32 37 100M * 0 0 TGCATGACAATTGCCTTGTCCCTGCTGAATGTGCTCTGGGGTCTCTGGGGTCTCACCCACGACCAACTCCCTGGGCCTGGCACCAGGGAGCTTAACAAAC DFGEGFDK;HFFHJJDJHFJJKILKDMIJFDKJMIMJKM@HAMIL=KKMHHLHM8GKKECMHJLHGM=BLMJIKKJLHJJKGHKIJJ@IHJFEEGHDBGB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR013140.19886608 177 17 33 37 108M * 0 0 GCATGACAATTGCCTTGTCCCTGCTGAATGTGCTCTGGGGTCTCTGGGGTCTCACCCACGACCAACTCCCTGGGCCTGGCACCAGGGAGCTTAACAAACATCTGTCCA %CCD@ACF?E@DBECDF@FHGFEDHEHGABBCC>@FFD>FCGKEELCIHLGKJJGCHHJDBCIIJJIFIJJGDGHCCGGEFFCAEGD: X0:i:1 X1:i:0 MD:Z:108 RG:Z:ERR013140 AM:i:37 NM:i:0 SM:i:37 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR243079.1328786 177 17 33 37 100M * 0 0 GCATGACAATTGCCTTGTCCCTGCTGAATGTGCTCTGGGGTCTCTGGGGTCTCACCCACGACCAACTCCCTGGGCCTGGCACCAGGGAGCTTAACAAACA DEDDICIGFGFIJHGFJGG?KGJCHKCHFICIKEHGFHGJDJ@ICIFEAGKBKC@CHFBKFBHFEGEDEJHHHIFJEGHHEDGHDHJHHJFCDDGCADE? X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243079 AM:i:37 NM:i:0 SM:i:37 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR243027.254838 177 17 36 37 100M * 0 0 TGACAATTGCCTTGTCCCTGCTGAATGTGCTCTGGGGTCTCTGGGGTCTCACCCACGACCAACTCCCTGGGCCTGGCACCAGGGAGCTTAACAAACATCT ?B.F)9:GCFJ=CGBD0DFG0AL5;;CHIH?8/F?C65G=E0=BBFD>BD? X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR156632 AM:i:37 NM:i:0 SM:i:37 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR016352.3774900 177 17 48 37 108M * 0 0 TTTCCCTGCTGAATGTGCTCTGGGGTCTCTGGGGTCTCACCCACGACCAACTCCCTGGGCCTGGCACCAGGGAGCTTAACAAACATCTGTCCAGCGAATACCTGCATC 4&4%4-<'CH>+GD8<6<<;85562@>C:>310155<+/4568-&,)8*7=6,9;D261>CG@6?@>/H=8@HB:FEFED@<>DB?-2?@=>BA9 X0:i:1 X1:i:0 MD:Z:1G106 RG:Z:ERR016352 AM:i:37 NM:i:1 SM:i:37 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR156632.8688512 113 17 48 37 100M * 0 0 TGTCCCTGCTGAATGTGCTCTGGGGTCTCTGGGGTCTCACCCACGACCAACTCCCTGGGCCTGGCACCAGGGAGCTTAACAAACATCTGTCCAGCGAATA DCF.AGFCKCGDBJILEK@CEKGHL9:B7GM<3F<:BH=FC0KC;HM:K;DKGCHLM?IG>@GMJFECHHGCDIIBEFI:GAHBCBDCD X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR156632 AM:i:37 NM:i:0 SM:i:37 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR243063.860385 113 17 58 37 100M * 0 0 GAATGTGCTCTGGGGTCTCTGGGGTCTCACCCACGACCAACTCCCTGGGCCTGGCACCAGGGAGCTTAACAAACATCTGTCCAGCGAATACCTGCATCCC AA@@FADGFKI?HCHFE@IFI:?GGJHFIIJIEBHFFKGFHIIHJ@HJHCLGIKGDHJHHIIJJIGFGEIGBGIGHJGGEGHJH@IEHEFGIFHIEBB>A X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243063 AM:i:37 NM:i:0 SM:i:37 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A +ERR162872.19371403 99 17 64 60 100M = 413 448 GCTCTGGGGTCTCTGGGGTCTCACCCACGACCAACTCCCTGGGCCTGGCACCAGGGAGCTTAACAAACATCTGTCCAGCGAATACCTGCATCCCTAGAAG BDGFHHEEGFIIHKJIIJDJKKHIKKIJEIIJIIIKLKLMKKILLLKJKIJLJMLLIMKKEHEGJFJKGKLLMJKJIMLCJIHFKJKIJEDKEGIEHD?F X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B +ERR162872.10929052 163 17 69 60 100M = 429 459 GGGGTCTCTGGGGTCTCACCCACGACCAACTCCCTGGGCCTGGCACCAGGGAGCTTAACAAACATCTGTCCAGCGAATACCTGCATCCCTAGAAGTGAAG E>EFFIJJKKIIJIHKKIJNLIIDKIHEKJLLMLLLKKJKJLJKGJNJIJKKMLIIIKGIKKKKHMKLHMKILLAJJJIKLJLLGILLJKJFDHDEGFD1 X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:F@CA@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162875.10099033 163 17 87 60 100M = 384 396 CCCACGACCAACTCCCTGGGCCTGGCACCAGGGAGCTTAACAAACATCTGTCCAGCGAATACCTGCATCCCTAGAAGTGAAGCCACCGCCCAAAGACACG D?DEGBHHIIIJKGHKKIGJKLJIBLJIGIFGJHGLEECAJIJCFJIKLGHI@KCFEJCJJJ3IJLGJKJLLIHHEGGJD?H4EHIADJE>D>7FCF@8* X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:C@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR243007.753594 99 17 95 60 100M = 555 559 CAACTCCCTGGGCCTGGCACCAGGGAGCTTAACAAACATCTGTCCAGCGAATACCTGCATCCCTAGAAGTGAAGCCACCGCCCAAAGACACGCCCATGTC ?ECDFG9FGH8EIGFHAIEHFHJFGG@JF?DGGEDEGGEKHIAJGFJI@GGFEGIEHEFHJHGEDHHHE@>@EK>HFHC@JFFDI3CEHHGAGEEECF@B X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243007 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D +ERR013140.20277196 163 17 97 29 34M74S = 339 349 ACTCCCCCGGCCCGGGGCCCGGGGGCTTTACAAAAAACTGTCCAGCGCATACCCGCATCCCCCCAAAAGAAGCCACCGCCCCAACACACACCCCCCACCCGCATAACC 824475'$-2)*#(/#%(/#(/-%-%-/%0/88800($,+3(*+..,%%+6%*#%2,/001)%%$2%%/$.%$00(,%+,1'*.%7(%&$&#'$$$#%#%#($+%+)" XC:i:35 MD:Z:6T0G4T2C0A2A3A4A5 RG:Z:ERR013140 AM:i:29 NM:i:8 SM:i:29 MQ:i:29 XT:A:M BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR013140.19887184 113 17 99 37 40S68M * 0 0 GTGTGTGTCGGGGGTGTCTGGGGTCTCACCCACGACCAACTCCCTGGGCCTGGCACCAGGGAGCTTAACAAACATCTGTCCAGCGAATACCTGCATCCCTAGAAGTGA %$($&$*+#%%#1'$$%2-'0&3*/$/$-73/69:7=1%2135??3C<6;:9@<46@G@EBB=FEBF<@95 X0:i:1 X1:i:0 MD:Z:108 RG:Z:ERR013140 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR013140.4461044 113 17 114 37 17S91M * 0 0 ACTCCCTGGGCCTGGCACCAGGGAGCTTAACAAACATCTGTCCAGCGAATCCCTGCATCCCTAGAAGTGAAGCCACCGCCCAAAGACACGCCCATGTCCAGCTTAACC /=1:/=44-348<0(910@955>D;??@=>>=<@DE?IIIHFJFJHGIHGHECCB@ X0:i:1 X1:i:0 XC:i:91 MD:Z:33A57 RG:Z:ERR013140 AM:i:37 NM:i:1 SM:i:37 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR245034.1618692 163 17 124 60 100M = 510 485 TAACAAACATCTGTCCAGCGAATACCTGCATCCCTAGAAGTGAAGCCACCGCCCAAAGACACGCCCATGTCCAGCTTAACCTGCATCCCTAGAAGTGAAG >ABDECDGFEHGHFHFFJF@GGGDGHHGJGFJHHHDKH@I@JGEGHGGJHBGHGHGCLGIHH@IGIFGKGHIAJIHHGEGHHIJFHIHHHEIECFCFBCE X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR245034 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@G +ERR245038.421367 177 17 131 37 100M * 0 0 CATCTGTCCAGCGAATACCTGCATCCCTAGAAGTGAAGCCACCGCCCAAAGACACGCCCATGTCCAGCTTAACCTGCATCCCTAGAAGTGAAGGCACCGC A>7EBHBFIGE>JEJFC/KFCKGEHGKFIJ@IEHD=JJJJCGACHEJGEHDFFFBGFFJHEGFIIKILHFFHHKGKJGFHHJEFJEHIGGEIGIIEE?C@ X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR245038 AM:i:37 NM:i:0 SM:i:37 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B +ERR156632.396790 177 17 133 37 100M * 0 0 TCTGTCCAGCGAATACCTGCATCCCTAGAAGTGAAGCCACCGCCCAAAGACACGCCCATGTCCAGCTTAACCTGCATCCCTAGAAGTGAAGGCACCGCCC >FDAGAHKICK>IBHJMJD?IFKILGEKAEJKLE:LKLGGCL1@KHGHKDMGCIKII@DH:KKHGLFIGCFLIJIHHGKJGJJHHHHJEIHGIFB@FA@B X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR156632 AM:i:37 NM:i:0 SM:i:37 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B +ERR243011.687269 177 17 133 37 100M * 0 0 TCTGTCCAGCGAATACCTGCATCCCTAGAAGTGAAGCCACCGCCCAAAGACACGCCCATGTCCAGCTTAACCTGCATCCCTAGAAGTGAAGGCACCGCCC ,G0I=C718G?2IB91/1FACI1?319I=IHADEF@DI5GBH5DJFHF=7;9G@G2DB5F?K2C;F.7G>7GCF9H=B<'GF?:BA1* X0:i:1 X1:i:0 MD:Z:71G28 RG:Z:ERR242939 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR243083.1184095 177 17 168 37 100M * 0 0 GCCACCGCCCAAAGACACGCCCATGTCCAGCTTAACCTGCATCCCTAGAAGTGAAGGCACCGCCCAAAGACACGCCCATGTCCAGCTTATTCTGCCCAGT CFG1F@CBDD>9HICI:@F=HIHIGDHPJBDFFG@IFEHKBDIJICJIELH?DEFHEHCGA8:@GBIJELIJ@HLE:LHKHEL:FDLKHE8IJGHJHDDLJLJIKFJLLLLJIHLGMHJJLLKJBJ8MIK>GLKK6HLKHJG7IEHIG@FCD X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR156632 AM:i:29 NM:i:0 SM:i:29 MQ:i:29 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR156632.15310883 163 17 201 60 100M = 519 417 AACCTGCATCCCTAGAAGTGAAGGCACCGCCCAAAGACACGCCCATGTCCAGCTTATTCTGCCCAGTTCCTCTCCAGAAAGGCTGCATGGTTGACACACA BCDFGHGFFGIIJGKHFKGKIILIJIIKCHLHJIILIJIJENHMGHLGJKILLKHIHHLKJMKKJHIHLKLJKJMJHBFJMFLLKJIIKAHHFFGGFFDB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR156632 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR245053.675620 163 17 213 60 90M1I9M = 408 294 TAGAAGTGAAGGCACCGCCCAAAGACACGCCCATGTCCAGCTTATTCTGCCCAGTTCCTCTCCAGAAAGGCTGCATGGTTGACACACAGTAGCCTGCGAC ?AHDDHEHEGJEIGGH@HHHGHGIFHGHBIIIHGHEIHHJJHGFFFGJLJGIEIFEKFJKHIHGKHEHHG=JJJGGJKFEJBHFJGGFICEHGCGGE=C8 X0:i:1 X1:i:0 MD:Z:99 RG:Z:ERR245053 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR013140.3521432 147 17 226 29 19S89M = 1 -313 CACCCCTAGAAGTGACGGCCCCGCCCAAAGACACGCCCATGTCCAGCTTATTCTGCCCAGTTCCTCTCCAGAAAGGCTGCATGGTTGACACACAGTGCCTGCGACAAA 71%??A9A792/7-2%(&:$::+BC@<=E>=EFCFHILHEDJNKHLFJFGGIMGGMMGKBKFMLELFMJJDEEJFJLIJIHIJFJHIHIFHEHIEGHJIFBGEJEFJIJGIDCFHICEEGDCA? X0:i:1 X1:i:0 MD:Z:99 RG:Z:ERR242975 AM:i:37 NM:i:1 SM:i:37 XT:A:U BQ:Z:@@A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR242943.1259162 163 17 236 60 67M1I32M = 565 428 GACACGCCCATGTCCAGCTTATTCTGCCCAGTTCCTCTCCAGAAAGGCTGCATGGTTGACACACAGTAGCCTGCGACAAAGCTGAATGCTATCATTTAAA ED?HCII?>H76E;=CDG=FJHDEDIAE?AB9@ X0:i:1 X1:i:0 MD:Z:99 RG:Z:ERR242943 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D@G +ERR245049.65948 113 17 237 37 66M1I33M * 0 0 ACACGCCCATGTCCAGCTTATTCTGCCCAGTTCCTCTCCAGAAAGGCTGCATGGTTGACACACAGTAGCCTGCGACAAAGCTGAATGCTATCATTTAAAA ?F@>HAHHFDBGGIGAIDCGFHJFKBDHHIHAMKGEGGDHIEEEHGJHJJHEHHGFJEJFHAGHJ@HIJJFIAJEJEEGJHHIEFGHHDFEIFCEBBA@? X0:i:1 X1:i:0 MD:Z:99 RG:Z:ERR245049 AM:i:37 NM:i:1 SM:i:37 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@DFFG +ERR162875.9416595 83 17 239 60 64M1I35M = 23 -314 ACGCCCATGTCCAGCTTATTCTGCCCAGTTCCTCTCCAGAAAGGCTGCATGGTTGACACACAGTAGCCTGCGACAAAGCTGAATGCTATCATTTAAAAAC 0?FGAHFHI?IKEHLFCK?DLH/?EBLIJEHKIMFKJLLHDFLJGJGLGHLFGKCHLILHIHJGHKBKJJCKGHHGGKJHJDEHIKGGGIFDEEDDCCFB X0:i:1 X1:i:0 MD:Z:99 RG:Z:ERR162875 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162872.21706338 147 17 246 29 100M = 1 -344 TGTCCAGCTTATTCTGCCCAGTTCCTCTCCAGAAAGGCTGCATGGTTGACACACAGTGCCTGCGACAAAGCTGAATGCTATCATTTAAAAACTCCTTGCT BB7EHGIKJJIJGFIIKFMKGIKKIILJBLKLEJ9IMMKKKJFLJGKKIHDLGMLHIMKMILEJILDGLLMKHIIKMMIJHLIDHJH>GHHKHIJFGEEB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:29 NM:i:0 SM:i:29 MQ:i:29 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR243047.1018873 99 17 254 60 49M1I50M = 653 498 TTATTCTGCCCAGTTCCTCTCCAGAAAGGCTGCATGGTTGACACACAGTAGCCTGCGACAAAGCTGAATGCTATCATTTAAAAACTCCTTGCTGGTTTGA @=CDDGGGI@HGJEEIJGIIJGEJFHHKIKHJJGGKBDEGDJEHGIFHEFKGHIHKCGCDFFFLJGGHHIKGF@HEGFBEDFHC=DJFCEHFFHECBC:/ X0:i:1 X1:i:0 MD:Z:99 RG:Z:ERR243047 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR243055.2002258 1187 17 254 29 49M1I50M = 653 496 TTATTCTGCCCAGTTCCTCTCCAGAAAGGCTGCATGGTTGACACACAGTAGCCTGCGACAAAGCTGAATGCTATCATTTAAAAACTCCTTGCTGGTTTGA A>A?DDH:HD>CGDBCE>65H9BGIK>JKFH<92.>J.;95FE3353+8839?/4H/.9CAE/ X0:i:1 X1:i:0 MD:Z:99 RG:Z:ERR243055 AM:i:29 NM:i:1 SM:i:29 MQ:i:29 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@G@C@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR245032.1218650 163 17 255 60 48M1I51M = 543 387 TATTCTGCCCAGTTCCTCTCCAGAAAGGCTGCATGGTTGACACACAGTAGCCTGCGACAAAGCTGAATGCTATCATTTAAAAACTCCTTGCTGGTTTGAG ?ACAFFGGFFFJDFJHHJIJIHKGGHKHHIJHHHJ7FFHGHFJHIGLEDIJIIIKBGIHGHIIJLGIFLJJEDKH@FBDHHHHJIJIHEKGHHIEACICE X0:i:1 X1:i:0 MD:Z:99 RG:Z:ERR245032 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C +ERR243071.874302 177 17 262 37 100M * 0 0 CCCAGTTCCTCTCCAGAAAGGCTGCATGGTTGACACACAGTGCCTGCGACAAAGCTGAATGCTATCATTTAAAAACTCCTTGCTGGTTTGAGAGGCAGAA @EEIGGEEIEIGCJGJFEIFJIICKHGLG?GJ3JEIFEGDCB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR156632 AM:i:29 NM:i:0 SM:i:29 MQ:i:29 XT:A:U BQ:Z:@I@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162872.6409758 163 17 293 60 100M = 651 457 GACACACAGTGCCTGCGACAAAGCTGAATGCTATCATTTAAAAACTCCTTGCTGGTTTGAGAGGCAGAAAATGATATCTCATAGTTGCTTTACTTTGCAT ECFGFHHHKFJJKLKJBIIKJCHKILFM>HHNKJF??IIHKHHLJNIEHHJJMFJILBIHHIEHIHMJJLJHEMCJIJJHLLIGJKLJLHHHJFKIIJILIHIHLJFHEKIHH?JGGGHIFEGCBCCA X0:i:1 X1:i:0 MD:Z:0C0A0G0T52G43 RG:Z:ERR162875 AM:i:25 NM:i:5 SM:i:25 MQ:i:60 XT:A:U BQ:Z:d^de@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C +ERR162875.15521446 83 17 314 60 100M = 41 -372 AGCTGAATGCTATCATTTAAAAACTCCTTGCTGGTTTGAGAGGCAGAAAATGATATCTCATAGTTGCTTTACTTTGCATATTTTAAAATTGTGACTTTCA EEEEGEFHLKHCJLDIDHHBIGHMJDMIGJLIJJJAELMLKKLMMKIGHGFKHHJGMJLHIKJIJLLDIHHLHIIGLIIIHEHGGGFEGGGFHIHDDEGB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162872.24509474 99 17 325 60 100M = 581 355 ATCATTTAAAAACTCCTTGCTGGTTTGAGAGGCAGAAAATGATATCTCATAGTTGCTTTACTTTGCATATTTTAAAATTGTGACTTTCATGGCATAAATA BDEEFDEEFGGFHKKJKGKKKKIGHHKJMJLBKJLJJHJHKHIJIKMLJJIMIIHJKIHHIMHIJMJIGJGHBHJHIJFLIKHJLFDKIJKIIFCCDBEB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D +ERR162875.16695705 163 17 332 60 100M = 647 414 AAAAACTCCTTGCTGGTTTGAGAGGCAGAAAATGATATCTCATAGTTGCTTTACTTTGCATATTTTAAAATTGTGACTTTCATGGCATAAATAATACTGG 79@(D+JGDCD7@KI&%=/HGC/BBA9<7>JH:1HI9=FFJI:;0,6H5D)A6IHH29EBAAB@DC( X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR013140.20277196 83 17 339 29 108M = 97 -349 CCTTGCTGGTTTGAGAGGCAGAAAATGATATCTCATAGTTGCTTTACTTTGCATATTTTAAAATTGTGACTTTCATGGCATAAATAATACTGGTTTATTACAGAAGCA 4AB@(8G1B?AFFFHJ>HGJJHH@HJHIGIHNIHHHLHKLHJKJIIJLKKGJHIHKKJIIIIHKKHKKIIKKLIGKKJIGHHHGHHGHHHJJFIIGFIFFGIHFFDA@ X0:i:1 X1:i:0 MD:Z:108 RG:Z:ERR013140 AM:i:29 NM:i:0 SM:i:29 MQ:i:29 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR013140.8214205 99 17 346 60 108M = 676 437 GGTTTGAGAGGCAGAAAATGATATCTCATAGTTGCTTTACTTTGCATATTTTAAAATTGTGACTTTCATGGCATAAATAATACTGGTTTATTACAGAAGCACTAGAAA @BCCFGIGIGHHIHJIJJGHKGHGJKJKGHIHHIJLIHHGLIIIJLHIHIIIIKFKIIIIJLHLIIKKHIKKKHILKHHJHHGKLMJHGGHEGDIGIHFEHCHDDFCB X0:i:1 X1:i:0 MD:Z:108 RG:Z:ERR013140 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@HHH +ERR243007.996298 1187 17 357 60 100M = 683 425 CAGAAAATGATATCTCATAGTTGCTTTACTTTGCATATTTTAAAATTGTGACTTTCATGGCATAAATAATACTGGTTTATTACAGAAGCACTAGAAAATG BDGEEFFFIFGEHKIKFHEKHEJIIAFFJIHDJIGFDHAFFEHHIIHJHJHHJDFIFFJIHHHFHHEEGJEJHIHGGDEHFFHHKHIKHHHIFIEGE?DD X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243007 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR243027.1412318 163 17 357 60 100M = 683 425 CAGAAAATGATATCTCATAGTTGCTTTACTTTGCATATTTTAAAATTGTGACTTTCATGGCATAAATAATACTGGTTTATTACAGAAGCACTAGAAAATG ADGEFFGFJHHEGJIIHGEJFEIIJEFDIIEGIIIGEGEFEEJHGHFJFJFHHFEKHHIFJHGGEJGDIIFHIMHGGFEGIFHHKIHMJGJFFGDFDEBD X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243027 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162875.23475567 163 17 362 60 100M = 503 240 AATGATATCTCATAGTTGCTTTACTTTGCATATTTTAAAATTGTGACTTTCATGGCATAAATAATACTGGTTTATTACAGAAGCACTAGAAAATGCATGT B?DHGBAHGGDGCHGFEIIEIEIFLGH=7G:DACIIJJ>AJGBBAAD5JA8E=F(CEBDFBB>CEDGDGEC1CDB=DAFCFEFHJACEFFF>@ACCACG=BCDBBBC@9 X0:i:1 X1:i:0 MD:Z:108 RG:Z:ERR013140 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR013140.11659627 163 17 375 60 108M = 645 360 AGTTGCTTTACTTTGCATATTTTAAAATTGTGACTTTTATGGCATAAATAATACTGGTTTATTACAGAAGCACTAGAAAATGCATGTGGACAAAAGTTGGGATTAGGA :FD@CDEABEEHCCHIHGGGDDDGJJJHEIGIJGJEE/HIJMKJIIKKIILIIHKKMGFEJJFIHKMLLMLKHHINKLLLIHKJGKGJFFAJCH1GFBFBHGD>BDB; X0:i:1 X1:i:0 MD:Z:37C70 RG:Z:ERR013140 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR013140.7259970 163 17 378 60 108M = 660 377 TGCTTTACTTTGCATATTTTAAAATTGTGACTTTCATGGCATAAATAATACTGGTTTATTACAGAAGCACTAGAAAATGCATGTGGACAAAAGTTGGGATTAGGAGAG :DEE??CCGBCGHGGFGDDDGJJJHEIHIJGJEEIIIJLKJIHKKIIKIIHKKMDGFIJFJIJMKJMLJHJJMKHJLJHKKGJGIIIGJGDDGF>JFDHE?BCECEEE X0:i:1 X1:i:0 MD:Z:108 RG:Z:ERR013140 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ABE +ERR162875.10099033 83 17 384 60 100M = 87 -396 ACTTTGCATATTTTAAAATTGTGACTTTCATGGCATAAATAATACTGGTTTATTACAGAAGCACTAGAAAATGCATGTGGACAAAAGTTGGGATTAGGAG 6BD0@6?BH;6BCHFE>6JJHHAEMJBALKIM18KBCHJB?IFIMJLBDKIHBFDGGEFJIIDIJHKFHAIJKKBHFJJGCHHFF>HGCDEEGED>DFGB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A@ +ERR156632.5355545 99 17 398 60 100M = 640 341 AAAATTGTGACTTTCATGGCATAAATAATACTGGTTTATTACAGAAGCACTAGAAAATGCATGTGGACAAAAGTTGGGATTAGGAGAGAGAAATGAAGAC C@C=FFJGGHHKGGLGHIJKJIHDJIIHIJJLNLHHHDFHIJDMFJLGMILHKGJKHILIJGJHLFJJJIJHLGIMMIHGGHLIKKHNJMIGFHIGEFBA X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR156632 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:D@A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162872.15901000 83 17 399 60 100M = 175 -323 AAATTGTGACTTTCATGGCATAAATAATACTGGTTTATTACAGAAGCACTAGAAAATGCATGTGGACAAAAGTTGGGATTAGGAGAGAGAAATGAAGACA CBD7GGIKHKHH@KJJLJHJHFHJHHKJHMKLKJHJHIJIMLMHKLLLNGJKJIHJJKLIHKJLKHMGIILIIIIKLIIIKHJJJJJJHFEGFGDHFFGB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:HGF@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR245053.675620 83 17 408 60 100M = 213 -294 CTTTCATGGCATAAATAATACTGGTTTATTACAGAAGCACTAGAAAATGCATGTGGACAAAAGTTGGGATTAGGAGAGAGAAATGAAGACATATGTCCAC FCEDHFEGGJGEEGEGFIFBKHFJIIGICEDJKKFHKKGLBJKGFDGEJKGHHGIKEHFEFGH:HIHKEGEIJKJJJJIJFEHGJGHIFIGEFGGECGCA X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR245053 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162875.15069550 99 17 412 60 100M = 742 429 CATGGCATAAATAATACTGGTTTATTACAGAAGCACTAGAAAATGCATGTGGACAAAAGTTGGGATTAGGAGAGAGAAATGAAGACATATGTCCACACAA AEEGDEFFAFCEEDH5HGHHDG>HIG7IJBCDBC?HI>F<@GJFAED@MGJILIHHII?JKHKHJGGGFGEJFGGGIGDEFGHB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162872.7627281 99 17 434 60 100M = 618 283 TATTACAGAAGCACTAGAAAATGCATGTGGACAAAAGTTGGGATTAGGAGAGAGAAATGAAGACATATGTCCACACAAAAACCTGTTCATTGCAGCTTTC BCCDDEFIGGJIGIJHIFIIBGKGIGKILIIHIGJJMHIKIKIHHIMGJLJKCMGDIJLIIMIKGKIJJIMBIKJIJIHIIJILKKHK@IDGIGIGH?=D X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR013140.15927236 99 17 441 60 108M = 653 319 GAAGCACTAGAAAATGCATGTGGACAAAAGTTGGGATTAGGAGAGAGAAATGAAGACATATGTCCACACAAAAACCTGTTCATTGCAGCTTTCTACCATCACCAAAAA @CEDGIEJFGIIIIFHIJGHHHIKGGGGJIHHIJJLHHHIJKJLJLJLJKIJLKJLHLIIIJJKJLHKHKIHGJEGJJGFJLIEIKKFFJFGFIGC;HHEHACF@BB= X0:i:1 X1:i:0 MD:Z:108 RG:Z:ERR013140 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A@AC@ +ERR162872.257723 163 17 452 60 100M = 628 275 AAATGCATGTGGACAAAAGTTGGGATTAGGAGAGAGAAATGAAGACATATGTCCACACAAAAACCTGTTCATTGCAGCTTTCTACCATCACCAAAAATTG DAEFIIFGKHKIIJJIEGMJILKKIFIHNCJLHMJMHHJILJILJJHIEJKHMKJJILJIEEEEKLFIFKJGIMKJLLLIIKLJJKDFLEIJHC>FEEC> X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:IFG@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR242971.1689116 163 17 452 60 99M1S = 861 508 AAATGCATGTGGACAAAAGTTGGGATTAGGAGAGAGAAATGAAGACATATGTCCACACAAAAACCTGTTCAGTGCAGCTTTCTACCATCACCAAAACTTC :>9A>6CGE::3ADE?G>ECBHGA12.AKC;I;?C>;D6;+F8JFBH.C<=2F@H.AF)G7H@,*9I;$9000F>9;3;4)D@E8(?8?:EDD?;B*C%/ X0:i:1 X1:i:0 XC:i:99 MD:Z:71T24A2 RG:Z:ERR242971 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@C@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@PNLT@W@@ +ERR156632.4899095 99 17 457 60 100M = 835 477 CATGTGGACAAAAGTTGGGATTAGGAGAGAGAAATGAAGACATATGTCCACACAAAAACCTGTTCATTGCAGCTTTCTACCATCACCAAAAATTGCAAAC DEDGFJIHHGIIILEGJJJJHHHLKILHLGLGIJHHJILJJJGJJKHLJKKIJJKIHJKMMMHILJIELLIOLLFIKLFJLGHLJJKJHJFGFDIHFCD= X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR156632 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR242943.1830749 163 17 457 60 100M = 890 532 CATGTGGACAAAAGTTGGGATTAGGAGAGAGAAATGAAGACATATGTCCACACAAAAACCTGTTCATTGCAGCTTTCTACCATCACCAAAAATTGCAAAC ABCBGIFCFFFHHJEDIGGBFDELIBF>J0IGGHGJFI==GCCABKBKHIGHLG?H?BH@HJ;?JGH;IIGLJIGDJI>HFIAEHEGEFEFGF>EFCDC< X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR242943 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR013140.29762488 163 17 466 60 108M = 716 350 AAAAGTTGGGATTAGGAGAGAGAAATGAAGACATATGTCCACACAAAAACCTGTTCATTGCAGCTTTCTACCATCACCAAAAATTGCAAACAACCACACGCCCTTCAA 9@>:?A=BAA??7@AGBABCCBD?H@?EA@B;EDADEEABEFG:GAB>>::?>><@@HDDCIEGD:A)BD<>C< X0:i:1 X1:i:0 MD:Z:108 RG:Z:ERR013140 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR242979.1294369 163 17 468 60 100M = 781 412 AAGTTGGGATTAGGAGAGAGAAATGAAGACATATGTCCACACAAAAACCTGTTCATTGCAGCTTTCTACCATCACCAAAAATTGCAAACAACCACACGCC ?AGDCGFGEDCBIGFIFJGJEHCGIGCHFFDEADIEGHHGFJHGGGGGJJHFFJGGAJHHKJJEGKCBGIHHKGHJFBIEEEFGJGHFIFFHFCFE6EG9GGICC@;HHILIHIICFEKJ<9JI9I<3J7I=EKBDF?A2FHIK2BFFJJD(J5E@F697?@ X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@AE +ERR243011.373069 83 17 483 60 100M = 18 -564 GAGAGAAATGAAGACATATGTCCACACAAAAACCTGTTCATTGCAGCTTTCTACCATCACCAAAAATTGCAAACAACCACACGCCCTTCAACTGGGGAAC <8BFHA>DFDHIC:H;D?BHHGDAH:JAH>FDHHEHHFJGHIIIAJJGFGMCB;JFGI2HHFFFAECG9H9ECIEEEHEJBAIEGJDEIDEIFFCBEAB? X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243011 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@BB@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162872.18011293 163 17 488 60 100M = 748 359 AAATGAAGACATATGTCCACACAAAAACCTGTTCATTGCAGCTTTCTACCATCACCAAAAATTGCAAACAACCACACGCCCTTCAACTGGGGAACTCATC EAEFIHHKHIIHIIKHKLJJKJJJIJJKHLLHILJIIMLIMKMGILNJJKJJMIKMIHKIHJILLJKGJJJJKJJJIEKLLMHLGAJKLEJEHHHHGFDA X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:D@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162872.8507187 99 17 498 60 100M = 764 365 ATATGTCCACACAAATACCTGTTCATTGCAGCTTTCTACCATCACCAAAAATTGCAAACAACCACACGCCCTTCAACTGGGGCAGTCATCAACAACAAGC B>8C1E0+B,;BG5<-+);K0EI@AI,(HEI2C2+J+F<)9KL1DDHG-=#2F1G)E:9HA?DICAGDE)B X0:i:1 X1:i:0 MD:Z:15A66A1C13A1 RG:Z:ERR162872 AM:i:37 NM:i:4 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162875.23475567 83 17 503 60 100M = 362 -240 TCCACACAACATCCTGTTCATTGCAGCTTTCTGCCATCACCAAAAAGTGCAAACAACCACACGCCCTTCAACTGGGGAACTCATCAACAACAAACTTGTG C.=7?7F7C.A1<83K9D299HH?@CM12C=B6>DDEECA X0:i:1 X1:i:0 MD:Z:9A1A20A13T53 RG:Z:ERR162875 AM:i:37 NM:i:4 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C +ERR162875.21460873 99 17 505 60 100M = 796 390 CACACAAAAACCTGTTCATTGCAGCTTTCTACCATCACCAAAAATTGCAAACAACCACACGACCTTCAACTGGGGAACTCATCAACAACAAACTTGTGGT 5E;:AD>BEF-7IJEF;6HBE3,IJGAG/J7I)GDKHF7B2;J;H2DICH1BBE(?>*4BB*@>L2>HG,,G*2:/87+8@21''.FDJ/AH;=*-C+6B*B70=IFD=D>E759'85?5<) X0:i:1 X1:i:0 MD:Z:99A0 RG:Z:ERR245028 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR245045.954816 163 17 517 60 100M = 913 495 TGTTCATTGCAGCTTTCTACCATCACCAAAAATTGCAAACAACCACACGCCCTTCAACTGGGGAACTCATCAACAACAAACTTGTGGTTTACCCACACAA >FDAFFCCGHGJGJEFIHEHHHGIFGIEHHHFGCILHHGJGGHIEGIDAHHIIEJFGGIKIJIFEHGFFGKGGEHIHH?FKHDEFHIFGCDGEHFFEEEC X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR245045 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A +ERR162872.2317332 163 17 518 60 100M = 701 282 GTTCATTGCAGCTTTCTACCATCACCAAAAATTGCAAACAACCACACGCCCTTCAACTGGGGAACTCATCAACAACAAACTTGTGGTTTACCCACACAAT DDCDGGGJJILJKHHJLGIKHJKJILKJJJJJGILJJJJIGJKJHJHDLKLJHLJCJKKIIKFKJLJHHKKJGJIGIHIKLHLFJJIHEDGBJGHFEFBB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR245038.1576181 99 17 519 60 100M = 949 529 TTCATTGCAGCTTTCTACCATCACCAAAAATTGCAAACAACCACACGCCCTTCAACTGGGGAACTCATCAACAACAAACTTGTGGTTTACCCACACAATG ?@ECECHHFJHHFEIHDIHFFJGIGGGGGGGFGHGHGHEHJJGGFIAIHFKFLHHJIJCHFG7IJKGGJGGIHIHHH@EGDKEGG;ADFHEGDEEEDDCF X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR245038 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@H +ERR156632.15310883 83 17 519 60 100M = 201 -417 TTCATTGCAGCTTTCTACCATCACCAAAAATTGCAAACAACCACACGCCCTTCAACTGGGGAACTCATCAACAACAAACTTGTGGTTTACCCACACAATG BGFEFHHIJKMAJJLJIJLIJIGJLGHHIIHJLJDHILHHKJHMGEILJMKIKFHMJ=LLLGFLJMIIHHHKHHLHHHIJJHJJJJGHGIIJGIFIEDCD X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR156632 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@B@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@F +ERR245032.1218650 83 17 543 60 100M = 255 -387 CAAAAATTGCAAACAACCACACGCCCTTCAACTGGGGAACTCATCAACAACAAACTTGTGGTTTACCCACACAATGGAAGACCACTTAGCAACAAAAAGG EDBCBEFFKKFGFIFEGJEJFBLIILGIHDEJHIIHJFGLGJHIJGFLGFJEFFLFIKHEHIGFFGIKEJEJEHGGIEIKDGJFLIEIJIDFIDDEDFBA X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR245032 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR243007.753594 147 17 555 60 100M = 95 -559 ACAACCACACGCCCTTCAACTGGGGAACTCATCAACAACAAACTTGTGGTTTACCCACACAATGGAAGACCACTTAGCAACAAAAAGGACCAAACTCCTG BE;A?IEHEAIIILADGFGAHGFIKFEIIIHHLFFJFDHEDDKGEIHIDHHEHIIHEIEIGGCHIFHI?EIGLHEJIJEFJFCEFIIJEHIECEIFEGC@ X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243007 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B +ERR242939.81544 147 17 565 60 100M = 152 -512 GCCCTTCAACTGGGGAACTCATCAACAACAAACTTGTGGTTTACCCACACAATGGAAGACCTCTTAGCAACAAAAAGGACCAAACTCCTGGTACATGCAA +./6&=F=9A-0H1)GD:@:C(AD-ID=?/>7C)>0@B@(I7/HGH?46GBE8G9C-DBIGC<@IFDE49DG.B;BJC??JEDHCCF=FDDDG9E3AIAD4IEG;FDCCDAEEEH?? X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR242943 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162872.26172147 147 17 569 60 100M = 478 -190 TTCAACTGGGGAACTCATCAACAACAAACTTGTGGTTTACCCACACAATGGAAGACCACTTAGCAACAAAAAGGACCAAACTCCTGGTACATGCAACTGA (7=C87CDG?6BAFIH8JDGBLHJBHA;JE@2>;I/AI=0=LEMEMI;KDD7;E3'=I;?B<7GHI7HEE7L4K65GHGJH/BLFDJHHIIIHJDC;EF2H+8@IHIE@%/FEKGLFI8@?CHA6JIH?IBAFF@MF20L4IDBGHBDJIIJJB%)%>G@#/IGGJIHJL?8GJAGK6GJJJJG;HHEAHGCBD X0:i:1 X1:i:0 MD:Z:15A28A16A4C0A32 RG:Z:ERR156632 AM:i:25 NM:i:5 SM:i:25 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A +ERR162872.24509474 147 17 581 60 100M = 325 -355 ACTCATCAACAACAAACTTGTGGTTTACCCACACAATGGAAGACCACTTAGCAACAAAAAGGACCAAACTCCTGGTACATGCAACTGACAGATGAATCTC DGFGCGJGHMHHKHHHMJKKEKJDJIDJKNJLIKIIKLLIKMGLMJMAJMKLHJLKGJHMKMILLHIIMJKNILJJIKJKLLHIKJLHKKKHHJFFFHCE X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR245024.739014 163 17 584 29 20M1D80M = 935 450 CATCAACAACAAACTTGTGGTTACCCACACAATGGAAAACCACCTAGCAAAAAAAAGGACCCAAATCCTGGTACATGCAACTGACAGATGAATCTCAAAC ?CCEEDGGGHFG2>H/C6J8EE<:HH080=2G03I.G,,;E0()I(0&:H,,IJDJ0J.-H)G@*./I0>I;D6;/0*/G8;09+.<-./7I9...8DD9 MD:Z:20^T17G5T6C10A2C35 RG:Z:ERR245024 AM:i:29 NM:i:6 SM:i:29 MQ:i:29 XT:A:M BQ:Z:@@@@@@@@@@@@@@@@@@I@d_@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR242959.1635151 99 17 588 60 100M = 998 509 AACAACAAACTTGTGGTTTACCCACACAATGGAAGACCACTTAGCAACAAAAAGGACCAAACTCCGGGTACATGCAACTGACAGATGAATCTCAAACGCT @?EBE@G?DHCBA>E:;FBFGD=@ECHEE=@6:72GIGEIIA;EJE8FHH5F6K6:AHGA??EK5(:D0BCEFG2IIHI9?G7E5GHAAAA8EFC3><1( X0:i:1 X1:i:0 MD:Z:65T33A0 RG:Z:ERR242959 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR016352.14628028 163 17 612 60 108M = 865 360 CACAATGGAAGACCACTTAGCAACAAAAAGGACCAAACTCCTGGTACATGCAACTGACAGATGAATCTCAAACGCATTCCTCCGTGTGAAAGAAGCCGGACTCACAGG ;D@DDACFDGGHCFGDIEFHGHFDHIFIJIJEEHGJJCHEHJIHBHDGHII8HFIGI9J@IFIGKFFBHAJJF>GIAE8IF=B:EE@G4F@@9:EAH@C;BF?3C<9320E-DGDJ*>EA@DF8369I1:D>D/-6F,H;H0EC?,AJG?.I)=/I%=FE/C*%%1<06F)#GECD:,< X0:i:1 X1:i:0 MD:Z:26C28T15T12A1A13 RG:Z:ERR243015 AM:i:25 NM:i:5 SM:i:25 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162872.7627281 147 17 618 60 100M = 434 -283 GGAAGACCACTTAGCAACAAAAAGGACCAAACTCCTGGTACATGCAACTGACAGATGAATCTCAAACGCATTCCTCCGTGTGAAAGAAGCCGGACTCACA HKBLLHIHFEGJFIGHHHCIKFIDJKIIDIIGIMDHKJGDAKBLGHLJKHJEHJIJ@GHFGGJFFGIFGEGFCA X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR156632 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C +ERR013140.11659627 83 17 645 60 17S91M = 375 -360 TTAGCAACAAAAAGGACCAAACTCCTGGTACATGCAACTGACAGATGAATCTCAAACGCATTCCTCCGTGTGAAAGAAGCCGGACTCACAGGGCAACACACTATCTGA %5?-$)89<=;9>(.144==2@>BD@>DBCDFIGFFIIEBF@HDFFFFCABDC@BC;CFFLCJGEJF15E*?:E2JCB(I/2)80DBH*G;K)**)-L0HCC?IGHBGFDLCEDDFBE8@KBC?FEC9?FECFFHFH>HAFI@FEHFHEHIEDG@GBJDF;GEHEHFIFBFJFFFBGBAFC? X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243047 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR243055.2002258 1107 17 653 29 98M2S = 254 -496 TGGTACATGCATCTTACAGATGAATCTCAATCGCATGCCTCCGTGTGAAAGAAGCCGGACTCACAGGGCAACACACTATCTGACTATATCATGGGAAACT A)+5C7EF18?'9C,8H-<-GD2-59+EDG,;HI9GC0K,1)5F789A3.-4.)(4<,?=,GFIHI**<*4>EF2E2CF>0.4GE0)>E@110EGCBCD? MD:Z:11A2G15A5T48G1T10 RG:Z:ERR243055 AM:i:29 NM:i:6 SM:i:29 MQ:i:29 XT:A:M BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D@@ +ERR013140.7259970 83 17 660 60 12S96M = 378 -377 ACGCCTGGTACATGCAACTGACAGATGAATCTCAAACGCATTCCTCCGTGTGAAAGAAGCCGGACTCACAGGGCAACACACTATCTGACTGTTTCATGGGAAAGTCTG 40&/81&8:/<<79BIILCEL:JKLIKGELFHIKJJJFJFJJLEMGIJLHHGOBGLL?CIJM;KLJEHGFGAFGCDB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR156632 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR013140.8214205 147 17 676 60 108M = 346 -437 ATCTCAAACGCATTCCTCCGTGTGAAAGAAGCCGGACTCACAGGGCAACACACTATCTGACTGTTTCATGGGAAAGTCTGGAAACGGCAACACCATTGAGACAGAAAA :;A>;:9685?>@CCECD;@D@H@EDI>CGLJCLFFMIKFKHIKKFHJKCKFMDFHMJJFLJHGKGJIJJKJEEJGJLIJIEEHAJIIDHHEKHFIGGGFEDDC@@?: X0:i:1 X1:i:0 MD:Z:108 RG:Z:ERR013140 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR243007.996298 1107 17 683 60 100M = 357 -425 ACGCATTCCTCCGTGTGAAAGAAGCCGGACTCACAGGGCAACACACTATCTGACTGTTTCATGGGAAAGTCTGGAAACGGCAACACCATTGAGACAGAAA ?>CE?D@HJF:?>EIFFFGGHEIKFBIKGJHJEJIJIHJFFJEIFKEGIJGJBJGIHJGJGGIHHEEIIFIGHIEGF@IIIFEIEGHGFGIGHDGFEA@? X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243007 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@CEE +ERR243027.1412318 83 17 683 60 100M = 357 -425 ACGCATTCCTCCGTGTGAAAGAAGCCGGACTCACAGGGCAACACACTATCTGACTGTTTCATGGGAAAGTCTGGAAACGGCAACACCATTGAGACAGAAA A7?E@DEIIEJ@GGIDFFEHJGJJHCJKGMIHGKHHIIJHFIFJFJGIFHEJEJIHICDIHGGBHGFIIFIFHHFFD@IHHAFIEEIGFFHHIDHGEA@? X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243027 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@CEE +ERR013140.3773682 99 17 697 29 108M = 1064 389 GTGAAAGAAGCCGGACTCACAGGGCAACACACTATCTGACTGTTTCATGGGAAAGTCTGGAAACGGCAACACCATTGAGACAGAAAACAGGTGAGTGGTTGCCTGGGG @ACFHHGIHGCJ?HJFKJJFKFDBIHJEHCEBHHHCHEFAJDF>DFFGFDEB?ADDBEEAFD@;;DDG@8A>:CB=DDBB:CCD@>D?HA42A>?8?/%3@,(=<986 X0:i:1 X1:i:0 MD:Z:108 RG:Z:ERR013140 AM:i:29 NM:i:0 SM:i:29 MQ:i:22 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162872.2317332 83 17 701 60 100M = 518 -282 AAGAAGCCGGACTCACAGGGCAACACACTATCTGACTGTTTCATGGGAAAGTCTGGAAACGGCAACACCATTGAGACAGAAAACAGGTGAGTGGTTGCCT CGD8BHH@AGFKCKHKLIKKG>ILFLJJIGGJILJJIJJIILHIL:LIEMJIIECKGHGCJGLIHMHJKHHIFKJDJKKGHGGKKHIHIIGFGEDEF@FB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:EI@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR013140.29762488 83 17 716 60 7S101M = 466 -350 GGACTCACAGGGCAGCACACTATCTGACTGTTTCATGGGAAAGTCTGGAAACGGCAACACCATTGAGACAGAAAACAGGTGAGTGGTTGCCTGGGGCCAGGGAACTTT )/4/1429@99+@?%BBDD<;:;=:6?84=<7<=;?7G=?869::6?8B2C;==>0:841>.,5C0?7DB4@@2@FGCBBC5AFCHGAC?BC< X0:i:1 X1:i:0 XC:i:101 MD:Z:7A93 RG:Z:ERR013140 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A@ +ERR013140.11567710 163 17 728 60 108M = 984 356 CTATCTGACTGTTTCATGGGAAAGTCTGGAAACGGCAACACCATTGAGACAGAAAACAGGTGAGTGGTTGCCTGGGGCCAGGGAACTTTCTGGGGTCATACTCTCTAT :DCCCDDFCGGGCCHHGHKKDJJKFIJIHJKJG=FJIKGJGKJIEKKLKHJMHLHGCGIH?GFFBHDD7BAF>?BHFHFD>D66>7+AECC)CB?.BAB98G<(A9DMHDJI/&F@D&/H(861<:G6..2/39681K36EH2: X0:i:1 X1:i:0 MD:Z:59T32T5G1 RG:Z:ERR162872 AM:i:37 NM:i:3 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@I@@ +ERR162875.14341769 99 17 736 60 100M = 979 342 CTGTTTCATGGGAAAGTCTGGAAACGGCAACACCATTGAGACAGAAAACAGGTGAGTGGTTGCCTGGGGCCAGGGAACTTTCTGGGGTCATACTCTCTAT BGHFCDGGEIGHGHCJGJJKGHDJFCILHIJJJKHJELJLHKIJGGKKJJLI9LHJILJHHLHKLLGLIKJGLJJ2JJH9@D?GHGEKKLHGJGIKJIKKIL;JLJH44ILGI@KHJIJKII8CKMGJBHGAKLIIJ?HLCIILGDKKHIHIEHDIKGKHFHHDFDBD X0:i:1 X1:i:0 MD:Z:86T5G7 RG:Z:ERR162875 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@F +ERR162875.20069376 99 17 747 60 100M = 975 327 GAAAGTCTGGAAACGGCAACACCATTGAGACAGAAAACAGGTGAGTGGTTGCCTGGGGCCAGGGAACTTTCTGGGGTCATACTCTCTATGTTGATTCTGG ADCDHGGHIHGGHHCGIHHHIIKGHGLJLIJHMIIJIJJLMILFMILLHGLKJLKNKMIKJLKJJJJMJGJLKLJJHMHJFJKJGMKFJLGHJGGEHHFC X0:i:1 X1:i:0 MD:Z:81T5G12 RG:Z:ERR162875 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@AB +ERR162872.18011293 83 17 748 60 100M = 488 -359 AAAGTCTGGAAACGGCAACACCATTGAGACAGAAAACAGGTGAGTGGTTGCCTGGGGCCAGGGAACTTTCTGGGGTCATACTCTCTATGTTGATTCTGGT :BDFDI?JEG77D?LLH8KFJGJFHKKLIILIGIJIKCGFILLJCKJGDEIMFMLEKILKIHKIHLJIIMFKLKJIJIGHKILIKGGHGGGHGEEGEDDB X0:i:1 X1:i:0 MD:Z:80T5G13 RG:Z:ERR162872 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR156632.3225464 147 17 749 60 100M = 579 -269 AAGTCTGGAAACGGCAACACCATTGAGACAGAAAACAGGTGAGTGGTTGCCTGGGGCCAGGGAACTTTCTGGGGTCATATTCTCTGTGTTGATTCTGGTG =DD1HEG%@;?7HH28GFCGLD>GDDCCECKDHGGBLAJHEHDJC63AK.BHKFHGIIHH<<7FCE=FE?BDFA X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR156632 AM:i:25 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@F@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C +ERR243083.371418 163 17 750 60 100M = 1106 455 AGTCTGGAAACGGCAACACCATTGAGACAGAAAACAGGTGAGTGGTTGCCTGGGGCCAGGGAACTTTCTGGGGTCATATTCTCTGTGTTGATTCTGGTGG ?EEFEGCF@EG@FFIFGHD X0:i:1 X1:i:0 MD:Z:64T5G29 RG:Z:ERR162872 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR242979.1294369 83 17 781 60 100M = 468 -412 AAACAGGTGAGTGGTTGCCTGGGGCCAGGGAACTTTCTGGGGTCATACTCTCTATGTTGATTCTGGTGGTGGAAACAAGACTGTCCCAGCCTGGGTGATA BBFHIIJHKIHJGJFDDIFMGJEGIJGHLGHFKGGIHGIGHKEFFHGILEJGIGHCJHHFJGGGGFGCA@ X0:i:1 X1:i:0 MD:Z:47T5G46 RG:Z:ERR242979 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:GG@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162875.21460873 147 17 796 60 100M = 505 -390 TGCCTGGGACCAGGCAACTTTCTGGGGTCATACTCTCTATGTTGATTCTGGTGGTGGAAACAAGACTGTCCCAGCCTGGGTGATACAGCGAGACCCCATC E0:ID<=A,5AF/F/H0BEE3LJ&:1EA*G4<:FKAJBC8@CJHH4ICD@,EJ9F4CIHFLH=LEM;AHBJIEKIMGDHDJDGFIJK1CDGCHH/HIEA= X0:i:1 X1:i:0 MD:Z:8G5G17T5G61 RG:Z:ERR162875 AM:i:37 NM:i:4 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR013140.14588577 147 17 807 60 108M = 571 -343 AGGGAACTTTCTGGGGTCATACTCTCTATGTTGATTCTGGTGGTGGAAACAAGACTGTCCCAGCCTGGGTGATACAGCGAGACCCCATCTCTACCAAAAAATTAAAAA BCCDGIKFF?HGEFAGGGKLJFJHLLHEIGFDFHHHIIKDGGEKDKKFMHHFFMJKKMLJKKGIJIHIJJJAIJIILLKIGIKIKGDKHCCCBBDEB?@@?: X0:i:1 X1:i:0 MD:Z:21T5G80 RG:Z:ERR013140 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR156632.18988851 147 17 822 60 100M = 667 -254 GTCATACTCTCTATGTTGATTCTGGTGGTGGAAACAAGACTGTCCCAGCCTGGGTGATACAGCGAGACCCCATCTCTACCAAAAAATTAAAAATTAGCTG ?CD@E?GAJILHIIIJHEJJH:FKKIACJGIHHFKGLLGMIKJKHHKLJLFJKJIKDICKIKDJKKGJJKKIHFFIGEKJFGFEFGHHEFDDFEEGFGF? X0:i:1 X1:i:0 MD:Z:6T5G87 RG:Z:ERR156632 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A +ERR156632.4899095 147 17 835 60 100M = 457 -477 TGTTGATTCTGGTGGTGGAAACAAGACTGTCCCAGCCTGGGTGATACAGCGAGACCCCATCTCTACCAAAAAATTAAAAATTAGCTGGGCATGGTGGTGC 2@FGIB?>JIKIJK*I9BEC=:HKLHKIJHKDFJJFLJIMIFKIHHKLKDKJKHGKLLHILILHEMKHGGIGHHHGFFEHGGJKKGJJIIFGFEGFDFDA X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR156632 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162875.21635478 99 17 854 60 100M = 1075 320 AACAAGACTGTCCCAGCCTGGGTGATACAGCGAGACCCCATCTCTACCAAAAAATTAAAAATTAGCTGGGCATGGTGGTGCATGCCTGTAGTCCCAGCTA BBEECHEFIIFIIFHKIAKKGJHJEAKKKJHILLLCKIHHCIH@JFDJIDJJCIIMLHLJKJIKJIIHFLEGIKELKJHGKGIHGDHEF? X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:DD@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR242971.1689116 83 17 861 60 100M = 452 -508 CTGTCCCAGCCTGGGTGATACAGCGAGACCCCATCTCTACCAAAAAATTAAAAATTAGCTGGGCATGGTGGTGCATGCCTGTAGTCCCAGCTATTCACAG 0>?=B,..4&.9D)B=A--EG97=I;;E1&'::7/:=@-;>3+5BCGGF=HB5I6-F6GGC*+D/1EG=-.2+@/?')?0.C@>E*=A@=2?E3A@:BC> X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR242971 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162875.1140280 163 17 863 60 100M = 1156 392 GTCCCAGCCTGGGTGATACAGCGAGACCCCATCTCTACCAAAAAATTAAAAATTAGCTGGGCATGGTGGTGCATGCCTGTAGTCCCAGCTATTCACAGTG DEFHIHJIIJJIIIKHIHIJMKDIMIJKGKKHHMMKJHKJJJHIIJGHJJKGICJMLLLCELJJMKFMIIJHIIJELLLFIEGKJMJMHKDGDHFCFCBD X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR016352.14628028 83 17 865 60 108M = 612 -360 CCCAGCCTGGGTGATACAGCGAGACCCCATCTCTACCAAAAAATTAAAAATTAGCTGGGCATGGTGGTGCATGCCTGTAGTCCCAGCTATTCACAGTGCTGAGGTGGG AB?E?D@A>>=DBGBGHFB?BHCAHEH>FIIEIFHCIHGGGGJLCEGDGIIFKBG@JJIGIHICJIFHIBIJEKJJEIKFBDKJKIJHIJJIIFJEIH@IGIGBECBA X0:i:1 X1:i:0 MD:Z:108 RG:Z:ERR016352 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A +ERR242943.1830749 83 17 890 60 100M = 457 -532 CCCATCTCTACCAAAAAATTAAAAATTAGCTGGGCATGGTGGTGCATGCCTGTAGTCCCAGCTATTCACAGTGCTGAGGTGGGAAGATGCTTGAGCCCAG B=D7EG5KCF>GEGBDDAHDFEFFF7FHIKEEEJJ=HIJHII:EDEI9E>GGBHHCLFCDIFCGAEKEIHIGCIHJGGGEGHGDGEFGHG8BB/4.?'BEH9.'HHIH9LIF9@%;AH(:A-0AJ=E=7A,EIF@=;IG<0KH6@F4)H9IG-E,2:G1E;GCAFIBHAGC6FHDGHGGF=CCDE,@A? X0:i:1 X1:i:0 MD:Z:63A36 RG:Z:ERR245028 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR245045.954816 83 17 913 60 100M = 517 -495 AATTAGCTGGGCATGGTGGTGCATGCCTGTAGTCCCAGCTATTCACAGTGCTGAGGTGGGAAGATGCTTGAGCCCAGGAGTTCAAGGCTGCAATGAGCTA AD>CGHAFFIKGIFIFHGJHIJAIIHJIGDHIGGJK=JDECHGIGKJHIILHKBIJFGIJEIFH>EK)=BI>)A8FAI1F@K@9FI1A>J9CC3@@2@E8CB)GGILA>+DK0BE-@8J<:I*97CCGD70D X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@F +ERR162875.20069376 147 17 975 60 100M = 747 -327 GATGCTTGAGCCCAGGAGTTCAAGGCTGCAATGAGCTATGATTGCGCCACTGCACTTTGGCCTGGACAACAGAGCAAAACCCTGTCTCTAAAAAAAGAAA BEGHGFHLLJKFLLMKLKIJLHLLLKIKJDIJMLLMIJJLIJJLDJKMHLKKKIMKIHKLKMKMMILIGMKKKKLIFHFLJKJJILJLHGGGGFFIHDAE X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@FFK +ERR162875.14341769 147 17 979 60 100M = 736 -342 CTTGAGCCCAGGAGTTCAAGGCTGCAATGAGCTATGATTGCGCCACTGCACTTTGGCCTGGACAACAGAGCAAAACCCTGTCTCTAAAAAAAGAAAAGAA DDFHJHH>JKKKIKJJLGMKKKJIMGIIKMLLJIKJJJJLAJKIIMKMJBKJIKHKKMIDLIJJJLLLJLKGGHIJJMAJILJLHHHHGFGKIFFFIFAD X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@CI +ERR162872.20029780 1171 17 981 60 2S98M = 736 -342 CGTGAGCCGAGGAGTTCAAGGCTGCAATGAGCTATGATTGCGCCACTGCACTTTGGCCTGGACAACAGAGCAAAACCCTGTCTCTAAAAAAAGAAAAGAA %2,G.I.6,B6H8@)):=8I3>F*0AAD6B?:=86/.BG5?5=L>DG6L=<64JJ6II-;;>FI>I>EE7DD58C5CM?IDFCL@HDHGFGECFFEHD@E X0:i:1 X1:i:0 XC:i:98 MD:Z:6C91 RG:Z:ERR162872 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@BJ +ERR243015.17606 83 17 982 60 100M = 618 -463 GAGCACAGGAGTTAAAGGCTGTAATGAGCTATGATTGCGCCACTGCACTTTGGCCTGGACAACAGAGCAAACCCCTGTCTCTAAAAAAAGAAAAGAAAAG :B@:.D9EBI53,(1:E3;E?74>*3+E=>B>B*-(@1*1H/1?GE+++0+,33:0C-,=BA9: X0:i:1 X1:i:0 MD:Z:4C8C7C49A28 RG:Z:ERR243015 AM:i:25 NM:i:4 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR013140.11567710 83 17 984 60 7S101M = 728 -356 TGCTTGAGCCCAGGAGTTCAAGGCTGCAATGAGCTATGATTGCGCCACTGCACTTTGGCCTGGACAACAGAGCAAAACCCTGTCTCTAAAAAAAGAAAAGAAAAGAAA /36>+5/+ABDF7EF9=DF>D;=C@9CCEIHGHGEBHCDFDH=?BE=A@AF=AGD@F;C>FJBDEFGHFEHFCBCCAFLHH@EJGEDEHGHGGEIGGFG8CBBI?=>? X0:i:1 X1:i:0 XC:i:101 MD:Z:101 RG:Z:ERR013140 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@CF +ERR242959.1635151 147 17 998 60 100M = 588 -509 GGCTGCAATGAGCTATGATTGCGCCACTGCACTTTGGCCTGGACAACAGAGCAAAACCCTGTCTCTAAAAAAAGAAAAGAAAAGAAAAACTCACTGGATA 6*?DFC8@>7.4ED9-DH=DB9)/I1:C6HC0BG:478)I8C=GDF1B/G*-GFC8+8H>9+D?I:8F2*,:DGIHDAFCC X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR156632 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@E +ERR162872.1587020 163 17 1024 60 100M = 1273 348 CTGCACTTTGGCCTGGACAACAGAGCAAAACCCTGTCTCTAAAAAAAGAAAAGAAAAGAAAAACTCACTGGATATGAATGATACAGGTTGAGGATCCATT EEGHGHJFGKIJKLLJIJIIJIMJNLKJKJJNMKLIJMMKHJKLLIJMKIJKMKJKJOIIKKGKLLKKLMMJGJJLJHILJIJJJLKHHKKLHGGHFCDA X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR156632.9494189 163 17 1031 60 100M = 1277 345 TTGGCCTGGACAACAGAGCAAAACCCTGTCTCTAAAAAAAGAAAAGAAAAGAAAAACTCACTGGATATGAATGATACAGGTTGAGGATNCATTATCTGAA BAFDFFHIFGGFHHGHHKHIHJGHKKJKIIKKLHIIIIIHNIJGILJIHKMIJIJJJLLILJLKKJIILJJIJJIIJGMCHHLELKIF!IHGGEGFED-E X0:i:1 X1:i:0 MD:Z:88C11 RG:Z:ERR156632 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:DC@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@J +ERR242943.1490060 99 17 1031 60 100M = 1433 501 TTGGCCTGGACAACAGAGCAAAACCCTGTCTCTAAAAAAAGAAAAGAAAAGAAAAACTCACTGGATATGAATGATACAGGTTGAGGATCCATTATCTGAA ?@G@FBGH>>DAFDEI>KGFDBBB97DH?=CIGE@FDED+K@776KDDEGGFGCIF7HDG7>JDFCBE@=CGBB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR242943 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:AB@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@DG +ERR245038.1101322 1187 17 1055 60 100M = 1338 382 CCTGTCTCTAAAAAAAGAAAAGAAAAGAAAAACTCACTGGATATGAATGATACAGGTTGAGGATCCATTATCTGAAATGCTTGGACCAGATGTTTTGAAT @AGIEGIIGEGDGGGGKGFFHJGEIGGFHHGIGIIGEHHFGHEGKGFFKGGDHHKHEEJIJJGFJHHJDEIIJJFHHGKBIFJGHFJCJAEIEEDCCCCB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR245038 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:BC@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D +ERR245049.1671108 163 17 1055 60 100M = 1338 382 CCTGTCTCTAAAAAAAGAAAAGAAAAGAAAAACTCACTGGATATGAATGATACAGGTTGAGGATCCATTATCTGAAATGCTTGGACCAGATGTTTTGAAT A@FHEHHIHDGGGGGHJEGHGKGHHHHGHHHHJJJGJIJJFHEHJGHFJEHFJHJHE@JGKGHGIGIHEGFHIJFHHCIJJFHGHHHGKFEHCDCDGCDB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR245049 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:CB@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D +ERR013140.3773682 147 17 1064 22 85S23M = 697 -389 GAGCCCCGCTGAGCGCAGAGGTCGGCGCTGCATGGAGTGGTCCCCCCCCCCCCCGTGTTGGGAACGAAAAAAAAAAAAAACCCCCAAAAAAAAAAAAAAAAAAAAAAA %3%$$$3(+8$$$-&7526&%4=$''%+7.2*,"&1%,/1#$$###$##%%%$$%1$+%$"%$/'##########$$$$$$$$##$#$$&$67%%$$$#$#$#$$6*/ XC:i:35 MD:Z:7G4G4G5 RG:Z:ERR013140 AM:i:29 NM:i:3 SM:i:29 MQ:i:29 XT:A:M BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@CBCCECUVDDCCCBCBCBCCUIN +ERR243091.615703 99 17 1066 60 100M = 1497 530 AAAAAGAAAAGAAAAGAAAAACTCACTGGATATGAATGATACAGGTTGAGGATCCATTATCTGAAATGCTTGGACCAGATGTTTTGAATTTTGGATTTTT ?BB@CHEE@EICFGGJGGHFGGGKGIFJHDGEGIDHFIFGEDDJFBFGBHICDKGIGFEIJHIEHEFKGGEJHFIHHLHHJC?CEJFEEBHGFFEFCIFFF@FIHFGDGHECEGI>=>GAGKJGEGF: X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR156632 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C@@ +ERR243003.852165 163 17 1147 60 100M = 1483 435 TTTTGAATTTTGGATTTTTTCATATTTTGTAATCTTTGCAGTATATTTACCAGTTCAGCATCCCTAACTCAAAAATTCAAAAATCTGAAATCCCAAACGC @?ACHFGFDEEIGGDFFGFFJGGDGFGFJFEGHKHFGKIHKEEGFHGFEIGHKGGJGKKHIKIJHGHIIHHDIHHIEKHG?IIHIFJGGHFGEHEEEF=A X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243003 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR013140.1880433 163 17 1154 60 108M = 1476 392 TTTTGGATTTTTTCATATTTTGTAATCTTTGCAGTATATTTACCAGTTCAGCATCCCTAACTCAAAAATTCAAAAATCTGAAATCCCAAACGCGCCAATAAGCATTCC :?@@CFEDBBCCCGHGGGDDDIEGJHIJEEJJILFHIBHEFHGKIMJFJJMKJIJLLKIHILKJLMLIJFLKLLLMIJKKLLHGJLLIKGGBH>JFJDFEGIGFC>CC X0:i:1 X1:i:0 MD:Z:108 RG:Z:ERR013140 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@EH +ERR162875.1140280 83 17 1156 60 100M = 863 -392 TTGGATTTTTTCATATTTTGTAATCTTTGCAGTATATTTACCAGTTCAGCATCCCTAACTCAAAAATTCAAAAATCTGAAATCCCAAACGCGCCAATAAG AA=GGFGHEHBIHDHJI==:?G???EJI@GK?BHIJJIIGJHHHJBBKKDCFLMDB@AILDCIEJJIFG@B@0A?:BC><9=C?@DAG<@;=>CCC>AABB:@=IIIIJAECEHGF@DCAEHIF6>9),<>B9<76$*)=2?5>8:7/*+2& X0:i:1 X1:i:0 XC:i:93 MD:Z:83T8T0 RG:Z:ERR013140 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162875.20797205 147 17 1190 60 100M = 895 -394 TATTTACCAGTTCAGCATCCCTAACTCAAAAATTCAAAAATCTGAAATCCCAAACGCGCCAATAAGCATTCCCTTTGAGCGTCATGTCGGTGCTTGGAAT @ECFEGHKJIFHHBJJCAKKLHHGNHMHEIIJEJMIIHFJHMJEIHHKLKMHHGEHDJKMIIEELLMJJHJJMEJLLLLEJHLIIJIDJIIIKEHIHDBE X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B +ERR242939.1378819 99 17 1202 60 100M = 1582 479 CAGCATCCCTAACTCAAAAATTCAAAAATCTGAAATCCCAAACGCGCCAATAAGCATTCCCTTTGAGCGTCATGTCGGTGCTTGGAATGTTTGGGGTTTT =C6:EADGG?;FGCIGFHHGF5IG?H>GCICJD;G?DG9HHHE4@AJDCCEAGIAFD5I,6H=5JAHJ4EJCHK2DAG=JEEDK8836E@ECH///A?=* X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR242939 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR243035.1352953 99 17 1224 60 100M = 1563 438 CAAAAATCTGAAATCCCAAACGCGCCAATAAGCATTCCCTTTGAGCGTCATGTCGGTGCTTGGAATGTTTGGGGTTTTGGATTTACAGCTTTGGGACGCT @D@EEFGHFIG?DGIHHHHFBAIBIFHHEFBJHHHEHIGGGEIDMBBFJGGFFEAGEMHHF> X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243035 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162872.18681977 147 17 1234 60 100M = 1084 -249 AAATCCCAAACGCGCCAATAAGCATTCCCTTTGAGCGTCATGTCGGTGCTTGGAATGTTTGGGGTTTTGGATTTACAGCTTTGGGACGCTCAACCTGTAC 0@75A@E9F:(18K.@;I@2L2E:B?DJHCEJJKL36IIIB7B?CK?*KJI+LGIJ9=JJAL?BJJGJCJGJJGHILGLJICB@AGDD<>ED?9@?DD/=>=0I>=:EA2L7;3ECK5;G=>@MKL/0A2>A89?<2>KF@>L<9;/7>I@4:5:AFD7I@5A@G6E X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR156632 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@G +ERR162872.9427750 163 17 1249 60 100M = 1421 271 CAATAAGCATTCCCTTTGAGCGTCATGTCGGTGCTTGGAATGTTTGGGGTTTTGGATTTACAGCTTTGGGACGCTCAACCTGTACCTCAATAAACCTGAT ECDFFGKJIHHJKLLHHLLLLDIMGILHMDKHLLLEKKHIIDGIILGKJDIIEIK@JHIHIKNMMJIMKJJJDLLLJDILLMI@HKIKF>FHCAFGGHBD X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@F +ERR162875.5181154 163 17 1266 60 100M = 1395 228 GAGCGTCATGTCGGTGCTTGGAATGTTTGGGGTTTTGGATTTACAGCTTTGGGACGCTCAACCTGTACCTCAATAAACCTGATTTTAAAAAAGTTTGGGG BCHHBGGFHIFJDDHJJLFJJ?DJMIHHKJGGGDGGHB9KGDBF@FKKHBJ6BI@DJJMIJC@IJIIKKLGAIKGHIHKJLIHHGGG=?GIFK8D:CA@= X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@EFGE +ERR162872.1587020 83 17 1273 60 100M = 1024 -348 ATGTCGGTGCTTGGAATGTTTGGGGTTTTGGATTTACAGCTTTGGGACGCTCAACCTGTACCTCAATAAACCTGATTTTAAAAAAGTTTGGGGGGATTCC @EED@HGGII@IJKIJIHIHILKKIJIIIKKKHJHFILLNGJJKJLDEMMILGJLLKIJHIMJJHJIGHGIMGKIIIHHHGGGGKIHHGHIHGGGFCE>B X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@G +ERR156632.9494189 83 17 1277 60 100M = 1031 -345 CGGTGCTTGGAATGTTTGGGGTTTTGGATTTACAGCTTTGGGACGCTCAACCTGTACCTCAATAAACCTGATTTTAAAAAAGTTTGGGGGGATTCCCCTA 3EDF/DGGHKHHJJEIJKMJJJJJKM/IKGKGH@LMGEJ1MLBHFG@EEEFIHEGFFEHHJKIGGJHGGI;JIJHHHIIIDEJHKJHGIEIHIHFJFGEEGGGFGIHIFE@HIDBFHGGIJHHHFDGFIFH@GECDC> X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR242963 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A@ +ERR156632.10697401 99 17 1297 29 54S46M = 1427 229 ACCCCAAACATTCCAAGCACCGACATGACGCTCAAAGGGAATGCTTATTGGCGCGTTTGGGATTTACAGCTTTGGGACGCTCAACCTGTACCTCAATAAA DAFCIHHGHHFGCKHFKGIJMDIIJHKGJALCKDDILKCCEHKLLGIJGLIKEIADIHLKLJFEHFJKLLMFGIK?IGEHLE@EIBGLGFDHIHHFCD:; MD:Z:4T41 RG:Z:ERR156632 AM:i:29 NM:i:1 SM:i:29 MQ:i:29 XT:A:M BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@NQVUYXY@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162872.17780862 147 17 1308 60 100M = 951 -456 ACAGCTTTGGGACGCTCAACCTGTACCTCAATAAACCTGATTTTAAAAAAGTTTGGGGGGATTCCCCTAAGCCCGCCACCCGGAGACAGCGGATTTCCTT 5EGFHJHIIDJJHEAFJKJHHGHJJGKKIFGGGFEHCIEEFDEIJJJJAHFFIFLLLLILJHHK>ILKHIL?DDFGA5DA;A7:DD?CFI:BAD@@B@B X0:i:1 X1:i:0 MD:Z:108 RG:Z:ERR013140 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR242951.1253490 99 17 1327 60 100M = 1717 489 CCTGTACCTCAATAAACCTGATTTTAAAAAAGTTTGGGGGGATTCCCCTAAGCCCGCCACCCGGAGACAGCGGATTTCCTTAGTTACTTACTATGCTCCT @BEFEDGGGIGFHFGGGJKJGHFFFFHGFHIJDEEKGFHJIDFEDKJIIEIJJDJAJJIIHIB@HJCJGJJBG?G=EGJGEAJKEEGHCEFH>BHCCFED X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR242951 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@F +ERR162875.7604876 99 17 1336 60 100M = 1673 436 CAATAAACCTGATTTTAAAAAAGTTTGGGGGGATTCCCCTAAGCCCGCCACCCGGAGACAGCGGATTTCCTTAGTTACTTACTATGCTCCTTGGCCATTT BECF-@EFHIIGHFGGGHHHHEMHHHKKDJIJCFCLKKKKGIJDK9AMJJAELCCJKBHIBCDFJ@IGJKKHBBIHDJKDFIK2IJFLJIGEFHDG8FB? X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A@@ +ERR245038.1101322 1107 17 1338 60 100M = 1055 -382 ATAAACCTGATTTTAAAAAAGTTTGGGGGGATTCCCCTAAGCCCGCCACCCGGAGACAGCGGATTTCCTTAGTTACTTACTATGCTCCTTGGCCATTTCT DAA>CEGGHFHHGDGHBFFKFHHCI>GEHIH5HGIHKDFIBHHAH=JCII?EEHGEJIKAGHGGCEEJCEGIGEEJ:DFIEGGIJFDJHGFEEHCECDE? X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR245038 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR245049.1671108 83 17 1338 60 100M = 1055 -382 ATAAACCTGATTTTAAAAAAGTTTGGGGGGATTCCCCTAAGCCCGCCACCCGGAGACAGCGGATTTCCTTAGTTACTTACTATGCTCCTTGGCCATTTCT CBBB@GICHFG?E7FEGFFIHHIIIJGLIKHHHJHKKFFHJHFAKIJFIHBGJHIGIIJAIJHGEDIJHDIHGEEKGDFIEGGIIGDJFHGHEHEDCEE? X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR245049 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR245041.487129 147 17 1368 60 100M = 1004 -463 ATTCCCCTAAGCCCGCCACCCGGAGACAGCGGATTTCCTTAGTTACTTACTATGCTCCTTGGCCATTTCTCTAGGTATTGGTATATTGTGTCTGCTGTGA ?DCEGGJCAHGHHAJHJEEHCKKHHEKIIBIINGGFDLIBJHHFGKHFFKEHHIKGJIHIHIJIGHGFKFLFIIHEGGFIIDEFGHGHGICJGHIGGEDA X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR245041 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C +ERR162875.4511615 163 17 1375 60 100M = 1652 376 TAAGCCCGCCACCCGGAGACAGCGGATTTCCTTAGTTACTTACTATGCTCCTTGGCCATTTCTCTAGGTATTGGTATATTGTGTCTGCTGTGAACTGTCC EA9IHD>CAD6A>K+A=23J>5:?K+0G?17<+G;<79:F=?CCH;<6/J6KCG0JB@HH)EKIFDMBDDB@EKDDGADAABECFDFDHBHBDGFEBE?DEC>@=@:GB@96#E?:42<72%9764;2( X0:i:1 X1:i:0 XC:i:99 MD:Z:91T7 RG:Z:ERR013140 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR156632.4998889 83 17 1385 60 100M = 1122 -362 ACCCGGAGACAGCGGATTTCCTTAGTTACTTACTATGCTCCTTGGCCATTTCTCTAGGTATTGGTATATTGTGTCTGCTGTGAACTGTCCTTGGCCTGTT .@2AGHJG8EHJ?JJFHIC/MFGEBAG6J;?@MCKH@FIBHDID7J?E=I;I9=HGG@EGFFFF?CBB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B +ERR162875.16344032 99 17 1402 60 100M = 1670 367 TTCCTTAGTTACTTACTATGCTCCTTGGCCATTTCTCTAGGTATTGGTATATTGTGTCTGCTGTGAACTGTCCTTGGCCTGTTTGGTGACGGGTGAGGAG ABFDHDCIFEFGJFEGFFGHBKLKKCG=KKIJFHFLDIFJMCBJHG6GEIIIGLHLGLKKKM@GL4JEKKDLKMEJCJJFIGI>CLFC X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR245032 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B@C +ERR162872.9427750 83 17 1421 60 100M = 1249 -271 GCTCCTTGGCCATTTCTCTAGGTATTGGTATATTGTGTCTGCTGTGAACTGTCCTTGGCCTGTTTGGTGACGGGTGAGGAGCAGGGACAGAAGGGTCCTG ;FA@GAFJJHF;>:GMIEHLKIIJHJLKIJIHHJKJKIMKKMHJJMIIIHJJJJCEKFKLHIGJFNJGKICLLIGKKJKJIKKJJKGIIIEIGGFECGDB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162872.25752000 99 17 1426 60 100M = 1789 462 TTGGCCATTTCTCTAGGTATTGGTATATTGTGTCTGCTGTGAACTGTCCTTGGCCTGTTTGGTGACGGGTGAGGAGCACGGACAGAAGGCCCCTGCGTGC B@=>FC/=CEF>G<5CE+HHECIGCHHEFICHH9J/C9><.=;3H.G79M>D/=K.8CFHNB:BEA9G/8:&7E3K9C)8JDH2C2:-H,&.(>./(BG; X0:i:1 X1:i:0 MD:Z:78G10G0T9 RG:Z:ERR162872 AM:i:37 NM:i:3 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR242963.327784 163 17 1426 60 100M = 1781 454 TTGGCCATTTCTCTAGGTATTGGTATATTGTGTCTGCTGTGAACTGTCCTTGGCCTGTTTGGTGACGGGGGAGGAGCAGGGACAGAAGGGTCCTGCGTGC @GGDBGCGFIED>EJ@DIFDJAEGG?EKG>?J(JIIHBEEJ:D0F,?FG#G9J.FIFHGGF?HEGAH/F82-H9AB98== X0:i:1 X1:i:0 MD:Z:69T30 RG:Z:ERR242963 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR156632.10697401 147 17 1427 29 100M = 1297 -229 TGGCCATTTCTCTAGGTATTGGTATATTGTGTCTGCTGTGAACTGTCCTTGGCCTGTTTGGTGACGGGTGAGGAGCAGGGACAGAAGGGTCCTGCGTGCC CEF=8DGGHHIKEKKHHIGELJFHDGGIHJJDKJMKJKKKH=LGJJJKADKJJMFJKBHIFDEGCKDGIKIK;JKCJK2FGJJHFHEIHFGHFG@BFE@B X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR156632 AM:i:29 NM:i:0 SM:i:29 MQ:i:29 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@BG +ERR245024.1107845 99 17 1428 60 100M = 1785 456 GGCCATTTCTCTAGGTATTGGTATATTGTGTCTGCTGTGAACTGTCCTTGGCCTGTTTGGTGACGGGTGAGGAGCAGGGACAGAAGGGTCCTGCGTGCCC @:EDEFDEHHHIDJGDDGDIE>EEDF?JDHEKIIIIFCIE@H=CCFH>EDHJIGG>EAGI<-FF?FD9A@CD8 X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR245024 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B@ +ERR242943.1490060 147 17 1433 60 100M = 1031 -501 TTTCTCTAGGTATTGGTATATTGTGTCTGCTGTGAACTGTCCTTGGCCTGTTTGGTGACGGGTGAGGAGCAGGGACAGAAGGGTCCTGCGTGCCCTGCCT BADGDG?HGIFFDHIGDHGEGJFGHFKHGADIIJIILHJHGJJEE;BEEFDLIILKB:EIEEHK>IG;AM5FAKKKDKIFK@KBGKKIFFHKICFKFFBDFHC@@GFBGCA X0:i:1 X1:i:0 MD:Z:11T88 RG:Z:ERR156632 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:EG@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR156632.10970255 147 17 1440 60 100M = 1238 -301 AGGTATTGGTATATTGTGTCTGCTGTGAACTGTCCTTGGCCTGTTTGGTGACGGGTGAGGAGCAGGGACAGACGGGTCCTGCGTGCCCTGCCTTCACAAG +>DC7>>0HE,A+37HHA9HIDBA?H.A1A.F8?N5HKDJ9FJ54:D>EK2C2)>I9:=FD=<8IH=GH)/1EF@>;FA X0:i:1 X1:i:0 MD:Z:72A27 RG:Z:ERR156632 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR156632.9078489 99 17 1452 60 100M = 1710 357 ATTGTGTCTGCTGTGAACTGTCCTTGGCCTGTTTGGTGACGGGTGAGGAGCAGGGACAGAAGGGTCCTGCGTGCCCTGCCTTCACAAGCCCCTGGAAGGA C@BGFJGJJJJKHGHIJIKLIKJKHJHKKJLGHGIJ=MKHEKF>HJGJKMLIKMKDHDMFINLLBEIGIEGBIBHEFEDI@JEI>JIFKBJHEKJFIIHDGHAGGHIJBIIIKIBDJDHHJIKI>5GGCGGJJHHFHEBFDKFE@;IC=G?= X0:i:1 X1:i:0 MD:Z:9C90 RG:Z:ERR242983 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@AB +ERR245034.324906 163 17 1469 60 100M = 1786 416 CTGTCCTTGGCCTGTTTGGTGACGGGTGAGGAGCAGGGACAGAAGGGTCCTGCGTGCCCTGCCTTCACAAGCCCCTGGAAGGAAAGTTGTTTTGGGATCT ?DGCFDFDHFHGGICEGJCEJFIABG=GBJIFKHGJI@GFFHDGKHH3LHHJJABHHFKGMKKICEFGHGJGHHKFKF9FKI@HHB=FJA2D;:C@DC7@ X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR245034 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR013140.1880433 83 17 1476 60 37S71M = 1154 -392 TGGGTATTGGTATGTGGTGTCTGCTGTGACCTGTCCTTGGCCTGTTTGGTGACGGGTGAGGAGCAGGGACAGAAGGGTCCTGCGTGCCCTGCCTTCACAAGCCCCTGG 0%.*1%?0+(3+7%;#'2%8=44222;76%51(02/+5B/:C@<>CA6CA=I8JELF8F.G18.3F)GDEDAE70G--DJJGHK@)+=B0= X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR243003.852165 83 17 1483 60 100M = 1147 -435 TTTGGTGACGGGTGAGGAGCAGGGACAGAAGGGTCCTGCGTGCCCTGCCTTCACAAGCCCCTGGAAGGAAAGTTGTTTTGGGATCTCTGCACCCTCAGCC 9DBGG@F; X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR242947 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B@ +ERR242999.1133728 163 17 1503 60 100M = 1901 495 AGGGACAGAAGGGTCCTGCGTGCCCTGCCTTCACCAGCCCCTGGAAGGAAAGTTGTTTTGGGATCTCTGCACCCTCAGCCTGGACAACTTGTGCCCATCT >F7ABHDH;F?FAFD08&@L>0HIG5IH=JFHI8?58F58A62;>G) X0:i:1 X1:i:0 MD:Z:34A65 RG:Z:ERR242999 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162872.15752406 163 17 1509 60 100M = 1804 394 AGAAGGGTCCTGCGTGCCCTGCCTTCACAAGCCCCTGGAAGGAAAGTTGTTTTGGGATCTCTGCACCCTCAGCCTGGACAACTTGTGCCCATCTGGTGAC EEEFIDIGJJKKKCIKKKLKKLLLIL:IKJMGMLLLLKHIMFIIJMJHLIIIJIKHIKLKMLKKKKLLMKINLLLLKFIEJKJ?JIIKKJIDJJIFBDBC X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@E +ERR013140.17777881 83 17 1524 60 46S62M = 1188 -397 GCGTGTTGGGAGGGGGGGGGGGAGCGGGGACAGAGGGGCCCGGGGTGCCCTGCCTTCACAAGCCCCTGGAAGGAAAGTTGTTTTGGGATCTCTGCACCCTCAGCCTGG &)%%*$$$%##%#(##$$#%$*#-%$01-893-%#11$$2##$"&1*86>=<FGIGJHHIFHHJEIJHEJD4JCIJDJGDHFG9G=HCIB:FGBA8;9E@JFJBHBB8IBBCEC=EJ@B;8;C;@CC6 X0:i:1 X1:i:0 MD:Z:108 RG:Z:ERR016352 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR013140.28180864 163 17 1536 60 108M = 1849 387 CAAGCCCCTGGAAGGAAAGTTGTTTTGGGATCTCTGCACCCTCAGCCTGGACAACTTGTGCCCATCTGGTGACCCCTCACTCAGCCACTCGACTTCCACGACAGCCTC :B?>=595B?<==??CA>BA=BC4@9B==?A0:C>EB=@AB@>8=>8E;?A@E7;CF;B@=?.GADBA<@9$'17.?2B3C66@386&298 X0:i:1 X1:i:0 MD:Z:88C0A14G3 RG:Z:ERR013140 AM:i:37 NM:i:3 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR156632.18201416 99 17 1557 60 100M = 1954 496 GTTTTGGGATCTCTGCACCCTCAGCCTGGACAACTTGTGCCCATCTGGTGACCCCTCACTCAGCCACCAGACTTCCACGACAGGCTCCAGCCTCGGCACC DDCEEJF;HFILHKHLJJIKLLHHLIMJJGIDGIJGLHK9LHJDELM@HLKILMMKIFKLLJELGJJGDEHHKHM;IJAJIGL.BLKDHMIHIIA5GFA? X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR156632 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR243035.1352953 147 17 1563 60 100M = 1224 -438 GGATCTCTGCCCCCTCAGCCTGGACAACTTGTGCCCATCTGGTGACCCCTCACTCAGCCACCAGACTTCCACGACAGGCTCCAGCCTCGGCACCTTCAGC D986>>D=2B&HFI6I/D/A8EB@I3EA5GHG*FEH=C:;HIDD1/G;IFD3EFJ0D?D44I<:=FG;2H3<=@HIH;@>@JIIGH>?EII5CDDDGDD? X0:i:1 X1:i:0 MD:Z:10A89 RG:Z:ERR243035 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:F@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A +ERR242939.1378819 147 17 1582 60 100M = 1202 -479 CTGGGCAACTTGTGCCCATTTGGTGACCCCTCACTCAGCCACCAGACTTCCACGACAGGCTCCAGCCTCGGCACCTTCAGCCATGGACAGTTCCGCCAGC 0>D/&9C98=AG73#/8.4+0H?H,0'10K@=2G(+<:'C1(20.207D?C2+B?11H&==79J@B:A8>2GH)4@F;H7BB4F=GGHCE0FAGHCBH?JGGE=F;==;1@9<5:.>>0'/,6<=*0;<4:2?=@<>D@B1:<=:?@E@F?BD>8GHBHF;DGGEIBHEECBCD: X0:i:1 X1:i:0 XC:i:75 MD:Z:75 RG:Z:ERR013140 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162872.25518652 83 17 1632 60 100M = 1387 -344 CACGACAGGCTCCAGCCTCGGCTCCTTCAGCCATGGACAGTTCCGCCAGCGTTGCCCTCTGTTCTGCTGTTTTCTCTACCAGAAGTGCCCTTCCCTCCTC ;C0C/;)@F7,:KK@KGH(CJ<03-G;J.JFF@DC5/:8?GE@DF.A.EA3FI2AGMIMI?E3;F4JBJ@JGEBCK8EIKFHGJ@FDEH=FE7,405,0?GG%E1:D.8115<='E&82A6*IJE53:,*C:)HII:H#D;:D3FKC*8I;368?<0GMHHH?:.-GCJ3<8<-5'+/+BA X0:i:1 X1:i:0 MD:Z:57A42 RG:Z:ERR162875 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A +ERR242959.484376 99 17 1656 60 100M = 1972 415 CTTCAGCCATGGACAGTTCCGCCAGCGTTGCCCTCTGTTCTGCTGTTTTCTCTACCAGAAGTGCCCTTCCCTCCTCACCTGACCACTCTGGGGAAATCCC ADBGGJGIFGJGGCGKEFJH@KGGJKAGFHHGGIGFIEEIJHIFLGGEFIJGJEGHGKIELFLFECHEIHIHHJGIIHHJGFGIGHHJGIHDGGFDEFB6 X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR242959 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A@@ +ERR162875.16344032 147 17 1670 60 100M = 1402 -367 AGTTCCGCCAGCGTTGCCCTCTGTTCTGCTGTTTTCTCTACCAGAAGTGCCCTTCCCTCCTCACCTGACCACTCTGGGGAAATCCCTCAGCACCCTCCCT AC=@>A8:IJKBGJEJIIJFLHJIGKEKMHIEEE9(4986(1$75&8+B:?>EBD>FHFFIGGIFHBIIJMFGIBHHEEGFGCBHDLJHLEGFCJFC?GGEDFGDF@ELFECFEBFFHDJJJIGGFIHHGIFFDA@ X0:i:1 X1:i:0 XC:i:89 MD:Z:89 RG:Z:ERR013140 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162875.7604876 147 17 1673 60 100M = 1336 -436 TCCGCCAGCGTTGCCCTCTGTTCTGCTGTTTTCTCTACCAGAAGTGCCCTTCCCTCCTCACCTGACCACTCTGGGGAAATCCCTCAGCACCCTCCCTGAG DE?E:IFD7JGIK>KKJMHJIGDHHKGJEKDJMJMJHKLLKILIJLKLLFDJILFEM?L@KGI4DC=EHIGABH=?9G6F8JFGG@<8? X0:i:1 X1:i:0 MD:Z:73A26 RG:Z:ERR242963 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR156632.9078489 147 17 1710 60 100M = 1452 -357 CCAGAAGTGCCTTTCCCTCCTCACCTGACCACTCTGGGGAAATCCCTCAGCACCCTCCCTGAGCATACCCTACTCTGGCACAAGCCCACCCTGCAAAGCC CFHD9DDHIJF"*6JJMJJKEAFLMFLBKHCMFJELEEIFHA:KKMFLKFFBJKLCLJLIKLKKHHGJJLFFLGIGJKKFKGIHIIJGHHIGH@CCFE@B X0:i:1 X1:i:0 MD:Z:11C88 RG:Z:ERR156632 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:AA@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@BG +ERR245032.1136878 147 17 1713 60 100M = 1416 -396 GAAGTGCCCTTCCCTCCTCACCTGACCACTCTGGGGAAATCCCTCAGCACCCTCCCTGAGCATACCCTACTCTGGCACAAGCCCACCCTGCAAAGCCCCT ?BFAE@FF@FABDHABKGKCHIHFDIDHHKDIHKGHGJJFECIHKFEKF? X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR245032 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR242951.1253490 147 17 1717 60 100M = 1327 -489 TGCCCTTCCCTCCTCACCTGACCACTCTGGGGAAATCCCTCAGCACCCTCCCTGAGCATACCCTACTCTGGCACAAGCCCACCCTGCAAAGCCCCTGAGG B4EFFE5FAI7?K5JAHHFJDBKAJGIEIIHHG?ADIGCFIHJK1BJLEGJKG=H@KFDBFIIEAKFHEHIJEFDHGF?IAGFJGIIEEGGEFEHFEFB? X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR242951 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR242991.1183757 163 17 1719 60 100M = 2047 427 CCCTTCCCTCCTCACCTGACCACTCTGGGGAAATCCCTCAGCACCCTCCCTGAGCATACCCTACTCTGGCACAAGCCCACCCTGCAAAGCCCCTGAGGCC ?=?FDI@@HHGFJEHGIIGGGDHEHFJDHBEHIEEHHJHFBIHHJFHJDFHJFGGHC@IDHIEJJJIJCKHFJKEGDL@DIHHADF5 X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR156632 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162872.9045126 163 17 1733 60 100M = 1981 347 CCTGACCACTCTGGGGAAATCCCTCAGCACCCTCCCTGAGCATACCCTACTCTGGCACAAGCCCACCCTGCAAAGCCCCTGAGGCCCGCCCTGTGGCGTC EBHHGHJHIKKKKIKIIKNJLKKJMHJKHJLNLLLLKMJLLJKILKLLJJMLMLKLJLKILLLMKKILKILJIJLKLLKLKIMKKKKDKJIKGGGFF@DB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:C@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR156632.16941332 163 17 1735 60 100M = 2041 405 TGACCACTCTGGGGAAATCCCTCAGCACCCTCCCTGAGCATACCCTACTCTGGCACAAGCCCACCCTGCAAAGCCCCTGAGGCCCGCCCTGTGGCGTCTC BFFDE4EHIHHHGJHHFHJHJKKHKKHGKKKKLKKKILKIIHJMJKGIJLHKLJHHJJMFMIJJMILLLJJBLLKKJLLHMKILLEKEJIGBIII@FEGA X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR156632 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C@ +ERR162872.10053578 99 17 1777 60 100M = 1965 287 CCCTACTCTGGCACAAGCCCACCCTGCAAAGCCCCTGAGGCCCGCCCTGTGGCGTCTCTCCCTCCCTTGCTGTCAGGACAGTGGTCCTGGCCTCCCGGGC BADGDEGEHIBGFFGHIAJKGIJJIJKHGHL7KFKKIJ=GJFJBCKJKADLBBEBJGMKJ;GLHLMECMLLLHH>BEBDI;H=38EEKCB?EK;H(===, X0:i:1 X1:i:0 MD:Z:92A2G4 RG:Z:ERR162872 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@RBO@DDD@ +ERR242963.327784 83 17 1781 60 100M = 1426 -454 ACTCTGGCACAAGCCCACCCTGCAAAGCCCCTGAGGCCCGCCCTGTGGCGTCTCTCCCTCCCTTGCTGTCAGGACAGTGGTCCTGGCCTCCGGGGCTCAC 4:<9CC1GEHC?69HI0?FD<713E9EFDH=B=HFEGDJ/E9FEE/DDFC? X0:i:1 X1:i:0 MD:Z:88A11 RG:Z:ERR242963 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR245024.1107845 147 17 1785 60 100M = 1428 -456 TGGCACAAGCCCACCCTGCAAAGCCCCTGAGGCCCGCCCTGTGGCGTCTCTCCCTCCCTTGCTGCCAGGACAGTGGTCCTGGCCACCGGGGCTCACGGAG 6DEGCEDF>HJC1BBIGHIE4;DHB>FGIHHICGBB>GFEGIDHD?ADD? X0:i:1 X1:i:0 MD:Z:64T35 RG:Z:ERR245024 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR156632.3514928 99 17 1786 60 100M = 2012 325 GGCACAAGCCCACCCTGCAAAGCCCCTGAGGCCCGCCCTGTGGCGTCTCTCCCTCCCTTGCTGTCAGGACAGTGGTCCTGGCCACCGGGGCTCACGGAGC C?EFGFFIGJEHFKLKJKIJJLDKLLKKIKHGHM6GLK9C@:>GJEMELI1EL:-6IE>L>B>3'2E/BBECJ;DDKINKDG:0H+3BM6@KNJH7B X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A +ERR243039.1277921 163 17 1809 60 100M = 2171 461 CCCTGAGGCCCGCCCTGTGGCGTCTCTCCCTCCCTTGCTGTCAGGACAGTGGTCCTGGCCTCCGGGGCTCACGGAGCCGCCCTGTGCCGTGTACCTCTGA <<=GGB40FE;BA>HHI7K:F4AIIABJHGGI:IHD?IHBACCDF@AD<>GADI&ED:)I<9AB10;I/IB6?EF:>3;AGGAHEEI9@9/051EEG@?? X0:i:1 X1:i:0 MD:Z:60A39 RG:Z:ERR243039 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:AA@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR013140.8706087 163 17 1811 60 41M67S = 2105 373 CTGAGGCCCGCCCTGTGGCGCCTCTCCCTCCCTTGCTGTCAAGACAGGGGTCCTGGCCTCCGGGGCCCATGGTGCCCCCCTTTGCCCAGGAACCCCTGGCTCGCTCCG 8C>@?>=;;4;>40465.<986B1?<5*:%'%).%".,#23$%*+0'$#%"%#)%+,$/.+(#&)#,%&%%'$,)$5$($'%%,&/%.%/5)%( X0:i:1 X1:i:0 XC:i:41 MD:Z:20T20 RG:Z:ERR013140 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR243007.241318 163 17 1823 60 100M = 2171 447 CTGTGGCGTCTCTCCCTCCCTTGCTGTCAGGACAGTGGTCCTGGCCACCGGGGCTCACGGAGCCGCCCTGTGCCGTGTACCTCTGAGCCCTCTGCACAGT =EHCIEH@EICJHK@IHJHHIEFI@EFIIK4AGGKEIBEJ7EC;:IHJF=1?KD.IHG8IGCJ>FHCIHHHFDDF6 X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243007 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR243015.41290 163 17 1834 17 100M = 2189 454 CTCCCTCCCTTGCTGTCAGGACAGTGGTCCTGGCCACCGGGGCTCACGGAGCCGCCCTGTGCCGGGCACCTCTGAGCCCTCCTCACAGTGCCTTCTTCTT <@BB3:GC>H>9II>1FGF26GB.B5:/>93?2&GD<8A2G3:EB3@*B:=8G)A652K40%?6&'&CGBDIHHJJ;FLIGFIIGIIGHBJGJJIJDLGIIGBEHGFJB@DEF@>D X0:i:1 X1:i:0 MD:Z:22A77 RG:Z:ERR243031 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR013140.28180864 83 17 1849 60 33S75M = 1536 -387 GCCGGCCCTGCGCCGTCTCCCCCGCCCTTTCTGTCAGGACAGTGGTCCTGGCCACCGGGGCTCACGGAGCCGCCCTGTGCCGTGTACCTCTGAGCCCTCTGCACAGTG '&1$$/-6%'((&,*%+%$$%.(%/36/+%1;06>?168<>2<;;:@D:79=>;@C9A:D=E9CBAAEACDE9?DCEDFCDEEGIADCBADEHGCGE?C@ X0:i:1 X1:i:0 XC:i:75 MD:Z:75 RG:Z:ERR013140 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR242983.836867 83 17 1849 60 100M = 1460 -488 TCAGGACAGTGGTCCTGGCCACCGGGGCTCACGGAGCCGCCCTGTGCCGTGTACCTCTGAGCCCTCTGCACAGTGCCTTCTGCTTGCCTGTGGCTTTGAG AFE@?CGHGBF@F2I-D4HED@@HD7BDGEEB>GDHBCJI5IHGEHE>HGCFEDEFHGEFG=EKGGDFGBAFCGCHJDGCFEHGGHEGCFF@:>@ACH7D@EB@BDDC;BD=?;7D>FDCF?3@%=?;8B@5?8?59@A5B@5D39?::9A?>1%$,-#9.1 X0:i:1 X1:i:0 MD:Z:15A92 RG:Z:ERR013140 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR016352.7109038 83 17 1854 60 108M = 1534 -427 GCAGTGGTCCTGGCCTCCGGGGCTCACGGAGCCGCCCTGTGCCGTGTACCTCTGAGCCCTCTGCACAGTGCCTTCTGCTTGCCTGTGGCTTTGAGAAGAAACCCCTTC $>;0776;FECG5GGJIJJJFJIIJGDJHJ;FJCFEFCCF@ECA X0:i:1 X1:i:0 MD:Z:0A14A92 RG:Z:ERR016352 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR242947.484791 83 17 1858 60 100M = 1499 -458 TGGTCCTGGCCACCGGGGCTCACGGAGCCGCCCTGTGCCGTGTACCTCTGAGCCCTCTGCACAGTGCCTTCTGCTTGCCTGTGGCTTTGAGAAGAAACCC 2EED@IGEHGJFHBHGJHMGLFAGJDJC?KG9LHHIIGCIHHFEJJIIGII9AJLEKHJICHIHFIFJIHKGJKHFFFKGIHDIJHFHJGIEGHCDEB?A X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR242947 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@DDG +ERR162872.17554044 99 17 1863 60 100M = 2053 289 CTGGCCACCGGGGCTCACGGAGCCGCCCTGTGCCGTGTACCTCTGAGCCCTCTGCACAGTGCCTTCTGCTTGCCTGTGGCTTTGAGAAGAAACCCCTTCT BFHBFFFFGCCGJJJIHHCGIKDI>KHKKIHLKKCDLHGIJJKKKILLKMJLLJIIJGMHKKIKHLLKIL@LLJJKGLHJIHGL?JIIKBDGEGHCECGE X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR242975.1004165 163 17 1881 60 100M = 2290 508 GGAGCCGCCCTGTGCCGTGTACCTCTGAGCCCTCTGCACAGTGCCTTCTGCTTGCCTGTGGCTTTGAGAAGAAACCCCTTCTGGTTATACATAAGACAGC @>EHGAAIHGHIEIJGAFIFEIGHJHJFKJGGIFIJKHJGLFJIFIGJKKJJFKJIHLFJIKJGFIHKIGIGFGIIIIIFJKHJGGEEDHGDBGIDFDGB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR242975 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D +ERR243031.1705886 99 17 1881 60 100M = 2179 397 GGAGCCGCCCTGTGCCGTGTACCTCTGAGCCCTCTGCACAGTGCCTTCTGCTTGCCTGTGGCTTTGAGAAGAAACCCCTTCTGGTTATACATAAGACAGC ?@DGFDAHGGHIEIIHAEIEFGHHIIIGKIHHJHGIJGIIKFJIHHEJKIIIGJJIJIFGIFJGCHIKIDJDBHEIIHJEJHIIEFGFDFCHCEGEFDFB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243031 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D +ERR162875.23402552 163 17 1882 60 100M = 2021 238 GAGCCGCCCTGTGCCGTGTACCTCTGAGCCCTCTGCACAGTGCCTTCTGCTTGCCTGTGGCTTTGAGAAGAAACCCCTTCTGGTTATACATAAGACAGCC DCHHICIIIJKHLJKDIKHIJKLJIKJLLKLJKHMLIKJNILJKLIMKLMMHKLLLMILLLLHIMIMAILKJIKILLLGKLMLIIIIGIGIIGKCGFGF< X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A@ +ERR162875.5605685 1187 17 1882 60 100M = 2021 238 GAGCCGCCCTGTGCCGTGTACCTCTGAGCCCTCTGCACAGTGCCTTCTGCTTGCCTGTGGCTTTGAGAAGAAACCCCTTCTGGTTATACATAAGACAGCC BAHEIAIIJJJGKKFCIKHGJLLJLK7LLKLFLJKJGHIKCLJKJGLKLKMFMLKJIEK05FFIJ@MD@N5E;III3IGKLMLECJAFGHHDDKCGD9C< X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR242971.738250 163 17 1883 60 100M = 2315 531 AGCCGCCCTGTGCCGTGTACCTCTGAGCCCTCTGCACAGTGCCTTCTGCTTGCCTGTGGCTTTGAGAAGAAACCCCTTCTGGTTATACATAAGACAGCCA AEDA@HEHHIDIIIAEIGEHHGIIJGLIHIKIHIKIBILGJJHGIJIJIIGJIIGJFJEHIFFLHLHGKGHGIIIIHEIJJJCF?GEAGFDHKGDEHED? X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR242971 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR242999.1133728 83 17 1901 60 2S98M = 1503 -495 GTTCCTCTGAGCCCTCTGCTCTGTGCCTTCTGCTTGCCTGTGGCTTTGAGAAGAAACCCCTTCTGGTTATACATAAGACAGCCAGAGAAGGGAGTTGCCC )+,7@CDG8F4'0>6066E%?/@;9>;5:?.816IK)2//DIBL97;EHC+@0,+2)4?1DG4GC<-E?D442EE3JB6H-%CHBCB;7G,,7F@C12*/ X0:i:1 X1:i:0 XC:i:98 MD:Z:0A16A1A78 RG:Z:ERR242999 AM:i:37 NM:i:3 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR242955.454193 163 17 1904 60 100M = 2322 517 TCTGAGCCCTCTGCACAGTGCCTTCTGCTTGCCTGTGGCTTTGAGAAGAAACCCCTTCTGGTTATACATAAGACAGCCAGAGAAGGGAGTTGCCCAGGGT ABFFDIBGDHCGHGHFGGDJJIFFHGHIDEHJHHJGHJJFHFJBIFHJHHAI9DAHGHIKHGDAH9CHHAILAJ?JLAFJEJGHIHAFGF9HEG9GG7GHJCE;CBGFGC X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243079 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162872.17357143 163 17 1931 60 100M = 2079 247 CTTGCCTGTGGCTTTGAGAAGAAACCCCTTCTGGTTATACATAAGACAGCCAGAGAAGGGAGTTGCCCAGGGTGGCACAGCACGTTGCTGCCAGTTACTG BEDHHIJJHH5J>HEKHLHIIIHEILKLJHLKKLGHHIJIJDEIMIKJMKDKNGM@IIKIKMIILHGEGED?ACDBG5>GG=.E@J8CHEFC?KFIK7HG2&E>D0IIJ=>9D-6FE>ACHIE0<649FC X0:i:1 X1:i:0 MD:Z:90G9 RG:Z:ERR243011 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C +ERR242975.806680 163 17 1953 60 100M = 2127 273 AACCCCTTCTGGTTATACATAAGACAGCCAGAGAAGGGAGTTGCCCAGGGTGGCACAGCACGTTGCTGCCAGTTACTGCCATTTTCACAGGCATGAAATG @AEDFGHEIHJHEFFGEIGGEHLHIHLIIHJFJGGJHIEKDGJIIHILEJFKIJHJGMJIIBFGJJFJKGGKFEFIJKKHEJDGFKBHHJGHGHIDDEDF X0:i:1 X1:i:0 MD:Z:88G11 RG:Z:ERR242975 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:BC@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@H +ERR242991.1140440 1187 17 1953 60 100M = 2127 273 AACCCCTTCTGGTTATACATAAGACAGCCAGAGAAGGGAGTTGCCCAGGGTGGCACAGCACGTTGCTGCCAGTTACTGCCATTTTCACAGGCATGAAATG @@EEHFGEHHJHFEEIDHHGHGKGIGJJHGKGLFHLGIGIFAIJHIGKJDEJGKGIHKJIHBHEKJIJJGJJFFFIDJLIHHEEDJHKGKDJEDIDCEDD X0:i:1 X1:i:0 MD:Z:88G11 RG:Z:ERR242991 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:BB@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@F +ERR156632.18201416 147 17 1954 60 100M = 1557 -496 ACCCCTTCTGGTTATACATAAGACAGCCAGAGAAGGGAGTTGCCCAGGGTGGCACAGCACGTTGCTGCCAGTTACTGCCATTTTCACAGGCATGAAATGG 36DEAGCKDKIIIIHHJFJGLL7KKH?K;LLH?IIMKLHIGHK0:LKJ?KA7KBJIIK>EFIIFMHHBEGBIFGLIIBKCIDHHJ@HHCCH>FFDCCEBA X0:i:1 X1:i:0 MD:Z:87G12 RG:Z:ERR156632 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR245038.798432 99 17 1958 60 100M = 2312 453 CTTCTGGTTATACATAAGACAGCCAGAGAAGGGAGTTGCCCAGGGTGGCACAGCACGTTGCTGCCAGTTACTGCCATTTTCACGGGCATGAAATGGAGAT ?DAEFG9CCCFCGFFEFHEGIIHEEHBJCEHGGFHBEDIG7DJEF3HHIFIHHIHFAFFIIJGJIF;EDEGHBFH9CDBGHFC>G/E:??FC@FBC@BCB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR245038 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR243087.1122947 99 17 1960 60 100M = 2366 505 TCTGGTTATACATAAGACAGCCAGAGAAGGGAGTTGCCCAGGGTGGCACAGCACGTTGCTGCCAGTTACTGCCATTTTCACAGGCATGAAATGGAGATAA ?DGFBC?D?DFGGDF>FIFGIHFK@KLGFGGEJDDFFFDFAFAG<><7I8>HG?AKEFEFFILCAHF<6B;IAIHCGBK@<5GIABDDAB5DC X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR245024 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@E +ERR162872.10053578 147 17 1965 60 100M = 1777 -287 TTATACATAAGACAGCCAGAGAAGGGAGTTGCCCAGGGTGGCACAGCACGTTGCTGCCAGTTACTGCCATTTTCACAGGCATGAAATGGAGATAACAACA .>@@DJHGBMKCHIK.LJKHHALILLFJDILHBBILGF>JKLIGDJFDCKIGGKEL;LEKIJIKJLBMGJAJJJFIIKKMHIDHGGIKJKIHFGGI:FFD X0:i:1 X1:i:0 MD:Z:76G23 RG:Z:ERR162872 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR242959.484376 147 17 1972 60 100M = 1656 -415 TAAGACAGCCAGAGAAGGGAGTTGCCCAGGGTGGCACAGCACGTTGCTGCCAGTTACTGCCATTTTCACGGGCATGAAATGGAGATAACAACAGGAGCGA 6BEFBHFHCGCIHKEIAJJJJGGIEIIFGHEEDICEJKIKF?IJHKFHIILGHGBGDEKHIHGGHFICBHHIHHGIEEEECIHIIEEEIDEIGFFFE>D@ X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR242959 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162875.2168867 99 17 1981 60 100M = 2205 323 CAGAGAAGGGAGTTGCCCAGGGTGGCACAGCACGTTGCTGCCAGTTACTGCCATTTTCACGGGCATGAAATGGAGATAACAACAGGAGCGACCGCACAGG AEGEHEEIGIGJGFJJIKIKJECLCFFJFLLHJDIILKILMLFMHFHKKLMKICIJIMJIDMKLJIJKIIILIIMDHIHHGJKILEJLH@HFCAJFFDGC X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@BA +ERR162872.9045126 83 17 1981 60 100M = 1733 -347 CAGAGAAGGGAGTTGCCCAGGGTGGCACAGCACGTTGCTGCCAGTTACTGCCATTTTCACGGGCATGAAATGGAGATAACAACAGGAGCGACCGCACAGG EC?HEBIEDELDIIJIJJKKEIGKJLHMLLLHCJJJDMJKGLKJJIIKJKLDKIJHJKFCIJJLIILGHJJKLKJHEGHIGFKIJKJHBIFEAGHFHGAB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR243003.755522 99 17 1982 60 100M = 2281 398 TGAGAAGGGAGTTGCCCAGGGTGGCACAGCACGTTGCTGCCAGTTACTGCCATTTTCACGGGCATGAAATGGAGATAACAACAGGAGCGACCGCACAGGC ?FDGE>GFDFFFECIIHGKHI4HCHDHDKJEHAFFHIAIGHGHFCEHGHJBGGGDEJFHB5IJGGJFFCGFHHFBGECFIGHGKCEK@?@G?@IFE@;E5 X0:i:1 X1:i:0 MD:Z:0A99 RG:Z:ERR243003 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:ZQ@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR156632.15198869 99 17 1987 60 100M = 2229 341 AGGGAGTTGCCCAGGGTGGCACAGCACGTTGCTGCCAGTTACTGCCATTTTCACGGGCATGAAATGGAGATAACAACAGGAGCGACCGCACAGGCTGCTG DD:=GKGFJJJHHJKKHIHKI>HLLGIDHHKLLJJMFLIIGJDJJKIJGGHKDKDJBLHFLJJJGLLGJJ?JDIAKJKMLJL=CIIJEC>IHLGHIEAED X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR156632 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR243059.1079565 83 17 1995 60 100M = 1638 -456 GCCCAGGGTGGCACAGCACGTTGCTGCCAGTTACTGCCATTTTCACAGGCATGAAATGGAGATAACAACAGGAGCGACCGCACAGGCTGCTGAGCGCGTC @DCGFEHG?EHJCJJIJB?HGHGJHIIHIJGEEKGHGIGIHG@ICGJGKKIHIEGFFIHCJGDEEJD?GHHFIKAIEGAHHDIGGIIFHJFHHG?E?DB@ X0:i:1 X1:i:0 MD:Z:46G53 RG:Z:ERR243059 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162875.4987821 163 17 1996 60 100M = 2242 345 CCCAGGGTGGCACAGCACGTTGCTGCCAGTTACTGCCATTTTCACAGGCATGAAATGGAGATAACAACAGGAGCGACCGCACAGGCTGCTGAGCGCGTCA DBDFJHHGJIKHIJMKJJDIEKKLLLKJMHIJJLKJMFIIGJJIKINIKKJLKFJJMBJNKJIJKKJKJKKJNJBKKKCKFKHLJMLLBKIHJIBGABFC X0:i:1 X1:i:0 MD:Z:45G54 RG:Z:ERR162875 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:C@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR245024.420543 163 17 1999 60 100M = 2317 417 AGGGTGGCACAGCACGTTGCTGCCAGTTACTGCCATTTTCACAGGCATGAAATGGAGATAACAACAGGAGCGACCGCACAGGCTGCTGAGCGCGTCACAC ?D@@EH@FGFFBHGG@ECAJFIJH@GDEEGEEIG?GFFGHGHFJIIHGKGHGEKFFJGHDHGGIIFJICEIA:HH;IHIGGHCHHHE:@:C9??BGE>A9 X0:i:1 X1:i:0 MD:Z:42G57 RG:Z:ERR245024 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR156632.3514928 147 17 2012 60 100M = 1786 -325 ACGTTGCTGCCAGTTACTGCCATTTTCACGGGCATGAAATGGAGATAACAACAGGAGCGACCGCACAGGCTGCTGAGCGCGTCACACGCAGCCATCGCGC 34F=D2JFAJF*>BBHKGKIEDEIAI@H@LKHJDKCHIGJKHLKHIGGKCHJCLGJIBK=KAKFHEHLKLGKLGEKI?I?GHIGFGBHHHHFFEG@F?DB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR156632 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR156632.9766143 147 17 2017 60 100M = 1732 -384 GCTGCCAGTTACTGCCATTTTCACGGGCATGAAATGTAGATAACAACAGGAGCGACCGCACAGGCTGCTGAGCGCGTCACACGCAGCCATCGCGCAGCTC HHKGGEFE5FBIHLHHEAFIGGHJEFAH@DFGFGFB X0:i:1 X1:i:0 MD:Z:36G63 RG:Z:ERR156632 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR013140.21458070 99 17 2020 29 90M18S = 2301 388 GCCAGTTACTGCCATTTTCACAGGCATGAAATGGAGATAACAACAGGAGCGACCGCACAGGCTGCTGAGCGCGGCACACGCAGCCCTCGCCGCGCCCCGGGGGAGTAC @BEFFFFFEJGCJJFGGHIJGJHIIKGIFJFGICCIKHHGEHKFIJJGJJALHLAGIDJEDFGHABFC>>1*128CBC:/1-=&1$1*'($('92%$#(7&%$%,%1. MD:Z:21G51T11A4 RG:Z:ERR013140 AM:i:29 NM:i:3 SM:i:29 MQ:i:29 XT:A:M BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR242983.1365156 163 17 2021 60 100M = 2397 475 CCAGTTACTGCCATTTTCACAGGCATGAAATGGAGATAACAACAGGAGCGACCGCACAGGCTGCTGAGCGCGTCACACGCAGCCATCGCGCAGCTCAGGG AAEHDDDGHIJHHGEDFJHHHKFIHGIDHGGGHHLHGEIJFHIILIGLGADHG@JGJHLILGJK>JGKKBJBEJFIHEAJHJIFFFIAJAHCJ=GHBEFB X0:i:1 X1:i:0 MD:Z:20G79 RG:Z:ERR242983 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@DB +ERR162875.23402552 83 17 2021 60 100M = 1882 -238 CCAGTTACTGCCATTTTCACAGGCATGAAATGGAGATAACAACAGGAGCGACCGCACAGGCTGCTGAGCGCGTCACACGCAGCCATCGCGCAGCTCAGGG :BFFBFBKIJKLHIIIFMDLKJKLIGEHHIIMMMMJIHIHHINLLLFJDLEJCKL;LHLILJCMJKJKCJCIILGKEDIHKIJJGHBIBHHIGIFHHCBB X0:i:1 X1:i:0 MD:Z:20G79 RG:Z:ERR162875 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B +ERR162875.5605685 1107 17 2021 60 100M = 1882 -238 CCAGTTACTGCCATTTTCACAGGCATGAAATGGAGATAACAACAGGAGCGACCGCACAGGCTGCTGAGCGCGTCACACGCAGCCATCGCGCAGCTCAGGG CFH>B6BII68FHC>B@@GLFJKFHCA?FIDIKLMJDC:LH9HLKGHFAM;JC2LHJHLILHIMFIKFADCFEKHKIE?HKKDJHHBIBHIIGFEHGCBB X0:i:1 X1:i:0 MD:Z:20G79 RG:Z:ERR162875 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:AA@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B +ERR156632.16941332 83 17 2041 60 100M = 1735 -405 GGGCATGAAATGGAGATAACAACAGGAGCGACCGCACAGGCTGCTGAGCGCGTCACACGCAGCCATCGCGCAGCTCAGGGATATTACGTGTAACTCGACA ?EEGEHIEFHCJKKJIGGFLHHLKLKILELHCEIHHLJLCMJLMKNLJDLEKKI=IHEKLKJKLIKCLDLLKKNILLLLLHHIJIHDIJHHGFIHAHFED X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR156632 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@C@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR243059.892087 147 17 2042 60 100M = 1719 -422 GGCATGAAATGGAGATAACAACAGGAGCGACCGCACAGGCTGCTGAGCGCGTCACACGCAGCCATCGCGCAGCTCAGGGATATTACGTGTAACTCGACAT DFGDEHEDHEHJHJHFGFJEFKGIKKIBKEDAJIDIJJJJHIJHJIHAIAFIKFG>@JFJJHJGFBJAJIJJHHJHHGLIFHIFF@GGHEGEJF@IDGB@ X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243059 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:FH@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR242991.1183757 83 17 2047 60 100M = 1719 -427 GAAATGGAGATAACAACAGGAGCGACCGCACAGGCTGCTGAGCGCGTCACACGCAGCCATCGCGCAGCTCAGGGATATTACGTGTAACTCGACATGTCAG EB?CDGDKK?KHJGKE:KFJHBBGBJEJ?J?BJK>IHJDH@H?GDDHGEHIHHHD>CADE@EHHEDEJFADFIEEEDGD? X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR242991 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR242991.1577744 1107 17 2047 60 100M = 1719 -427 GAAATGGAGATAACAACAGGAGCGACCGCACAGGCTGCTGAGCGCGTCACACGCAGCCATCGCGCAGCTCAGGGATATTACGTGTAACTCGACATGTCAG 0@?C7GAGIE@FHAC?HJGK X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR242991 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR243031.1324865 147 17 2047 60 100M = 1847 -299 GAAATGGAGATAACAACAGGAGCGACCGCACAGGCTGCTGAGCGCGTCACACGCAGCCATCGCGCAGCTCAGGGATATTACGTGTAACTCGACATGTCAG ECCE@GEIJGEFBIFFJHKHJHAIHIBKJFILIGKIKKHJKJBJAIFIGKEAJKJIKIHGAIAJLKLKGKIIHIHDHGFF@GGHEFDKGAIEIFFGEHDA X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243031 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162872.17554044 147 17 2053 60 100M = 1863 -289 GAGATAACAACAGGAGCGACCGCACAGGCTGCTGAGCGCGTCACACGCAGCCATCGCGCAGCTCAGGGATATTACGTGTAACTCGACATGTCAGCGATTG EGGEE?GJIIKLKKLLDLIKEKLJLLLLNKKMK?JLEMBIIMEMGELMJLJLIJDLDMLMKKIKLJLLJIIJJICIJJIEHLICKIK=HFIKJJCHFECD X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162872.360692 99 17 2070 60 100M = 2206 235 GACCGCACAGGCTGCTGAGCGCGTCACACGCAGCCATCGCGCAGCTCAGGGATATTACGTGTAACTCGACATGTCAGCGATTGTCACAGGCACTGCTACT 8DDB5DF:E=?BH;GKDFK5B?)GAF6@H2CIL?KF;J>JC3E8GHK?@.42I4BGHE7AC. X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162872.10955775 99 17 2073 60 100M = 2419 445 CGCACAGGCTGCTGAGCGCGTCACACGCAGCCATCGCGCAGCTCAGGGATATTACGTGTAACTCGACATGTCAGCGATTGTCACAGGCACTGCTACTCCT B?EEDEHEFHHHHIHIECJCHGHDIFACGKI7CGAD62LHLCHH6?IG3@CJCHF@K@:HIFLH8G@IHG1KEE@CG58@/HHJ@JJF@C@5JCFAHGF; X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR242979.559120 99 17 2075 60 100M = 2431 455 CACAGGCTGCTGAGCGCGTCACACGCAGCCATCGCGCAGCTCAGGGATATTACGTGTAACTCGACATGTCAGCGATTGTCACAGGCACTGCTACTCCTGG @CEEIGHHIIGIEJIBIBFJHGEGAIGOJDGHIBJAIDKJHKHJGJFGDHHEJCGIFEJGKLBFJHGJFHGKJCEHGHGLGIHKIKGMIKHHDGGEFDEG X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR242979 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@GL +ERR162872.17357143 83 17 2079 60 100M = 1931 -247 GGCTGCTGAGCGCGTCACACGCAGCCATCGCGCAGCTCAGGGATATTACGTGTAACTCGACATGTCAGCGATTGTCACAGGCACTGCTACTCCTGGGGTT AGFFIIFKH5=?DIJI>JBCKJLLIDHGDLEIMLEMGLIKJLIHHKIDCHIKJIFMJ?JHMIHJJMLBEI@IGBGJGKKJIKGKHIKHF>CBIFFEEE?B X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@B@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@AG +ERR243063.1642219 1123 17 2084 60 100M = 2462 477 CTGAGCGCGTCACACGCAGCCATCGCGCAGCTCAGGGATATTACGTGTAACTCGACATGTCAGCGATTGTCACAGGCACTGCTACTCCTGGGGTTTTCCA AEDEIGEAFECKHI-ACAGHI=HHHEFKB@HH1..F8=;76D4 X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243063 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR243063.246578 99 17 2084 60 100M = 2462 477 CTGAGCGCGTCACACGCAGCCATCGCGCAGCTCAGGGATATTACGTGTAACTCGACATGTCAGCGATTGTCACAGGCACTGCTACTCCTGGGGTTTTCCA AEGFIB@H@IJEHGICJGKIHHGJAI@JBHJDKDJEHHCE>B?HBAKFEHIGIAFHHHH@JHJHAFEEIFKFIHIGDIJJJHHEJIIHCIEFBAFABF=B X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243063 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR013140.8706087 83 17 2105 60 28S80M = 1811 -373 CGGGCGGGTGGGCGCTGCACACGCAGGCGTCGCGCAGCTCAGGGATATTACGTGTAACTCGACATGTCAGCGATTGTCACAGGCACTGCTACTCCTGGGGTTTTCCAT $$$&$$%&%%#(1-5-(4.=5:C=.&%8%C:F?CFH=GFCG@G?DAFFCB;=G5?.@BDGHACAGGDGCJGDECJHHDHHHFABA= X0:i:1 X1:i:0 XC:i:80 MD:Z:0A79 RG:Z:ERR013140 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR242999.1001077 99 17 2110 60 100M = 2438 427 GCAGCTCAGGGATATTACGTGTAACTCGACATGTCAGCGATTGTCACAGGCACTGCTACTCCTGGGGTTTTCCATCAAACCCTCAAGAGCTGGGCCTGGG @CEGFFGFIGGEFEGDEIAEIEEFIJJBGHFEJFJHKJBGGEJCI=IFLDHHHJJKJDIKLIIIFIID>G7DIHGIGJIIEIIJHGJFKKHGHGDGFFF= X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR242999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@HKC +ERR013140.30331713 163 17 2120 60 108M = 2444 431 GATATTACGTGTAACTCGACATGTCAGCGATTGTCACAGGCACTGCTACTCCTGGGGTTTTCCATCAAACCCTCAAGAGCTGGGCCTGGGGTCAACTTCCGGCCTGGG :DCCA?CC9FEDCGEI@@CFHGIBIEDB?EBDDEIIDIL=>FGE>DCDBFH;@ADBBC;=ADAC==CBBBC1;;A?BC>?FD>BF:DD8>/47=:AB:94;?@9DC?B X0:i:1 X1:i:0 MD:Z:108 RG:Z:ERR013140 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@EDH +ERR242975.806680 83 17 2127 60 100M = 1953 -273 CGTGTAACTCGACATGTCAGCGATTGTCACAGGCACTGCTACTCCTGGGGTTTTCCATCAAACCCTCAAGAGCTGGGCCTGGGGTCAACTTCCAGCCTGG ;CC>7<34<7=;.9??EECCH=FABGGFHHLJIIFHIHILJJJLLLLKIIHIKLLKJIHKGHGKHHIHKJKJGJIJHGIHFEFFFCB@@ X0:i:1 X1:i:0 MD:Z:58G49 RG:Z:ERR013140 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR243007.241318 83 17 2171 60 100M = 1823 -447 CTGGGGTTTTCCATCAAACCCTCAAGAGCTGGGCCTGGGGTCAACTTCCGGCCTGGGGAAACTGGGGCAAGTATCACCAGAGATGAGCTTTATAAAAATA CADB=EDBCB,H8GG2:08@HHFAI1;DCGG1HG=@CLAA?IG>GEFG=GHF?EH@>HGFGEDAHIEF9FDECDCCIBAHI>MGF3<0GFFA;6HC==;@6:H950BCG6>:E?BE:CGDFH?CDACDH2HJ;>HGA>CH:I>BD@BC=4ADA? X0:i:1 X1:i:0 MD:Z:49G50 RG:Z:ERR243039 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:B@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A +ERR243031.1705886 147 17 2179 60 100M = 1881 -397 TTCCATCAAACCCTCAAGAGCTGGGCCTGGGGTCAACTTCCAGCCTGGGGAAACTGGGGCAAGTATCACCAGAGATGAGCTTTATAAAAATAATGGTGCT @D:EFEGCFEI@KHJDJIJHKHHGKIKFHIJIHKFELHGFJJJHKHGIIKEDFKIGHJJJFKIGJIJCIKIJIIHGIIIKFGEGEFEDGHEEFHGGFFEA X0:i:1 X1:i:0 MD:Z:41G58 RG:Z:ERR243031 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:CF@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR243007.1719649 99 17 2188 60 100M = 2533 444 ACCCTCAAGAGCTGGGCCTGGGGTCAACTTCCAGCCTGGGGAAACTGGGGCAAGTATCACCAGAGATGAGCTTTATAAAAATAATGGTGCTAGCTGGGCA ?CC@FGEFIFIHHH>EHGIHH?CEIGCHIBJGEJHIHIHDFGFHGFCEGHHGHKEEGIGDHHJGLGGJIDJJCE=GGGG?IHC@HEDAIIGDIHFGGED@ X0:i:1 X1:i:0 MD:Z:32G67 RG:Z:ERR243007 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR243015.41290 83 17 2189 17 100M = 1834 -454 CCCTCAAGACCTGGGCCTGGCCACAACTTCCGTCCTGGGCAAACTGGGGCAATTATCACCAGAGACGAGCTTTATAAAAATAATGGTGCTAGCTGGGCAT @9>7D(.@B&.A111//.(4':-E4=/7,.),'DB=;0)1E<-E<<=3*1$B%'C/D-JH>H1-4*=1+>8DHCEHHHFH9GIJBIHGFDFF>GFJFKAG>IIKKK=GHJGAICEB@ X0:i:1 X1:i:0 MD:Z:14G85 RG:Z:ERR162872 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B +ERR013140.20581831 99 17 2212 60 108M = 2526 421 CAACTTCCGGCCTGGGGAAACTGGGGCAAGTATCACCAGAGATGAGCTTTATAAAAATAATGGTGCTAGCTGGGCATGGTGGCTTGCACCTGTAATCCCAGCACTTTG @CEBIFHI>HHJJHIIIJJJGKHIIJIKJIGHGJKHLKIJJKHILJJLFIFGFDFEHJEGHJHGJKLIJFIGEFGLHJKGJJGHBGGG>AHGFCBB?99=EBC=C70> X0:i:1 X1:i:0 MD:Z:108 RG:Z:ERR013140 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR156632.15198869 147 17 2229 60 100M = 1987 -341 AAACTGGGGCAAGTATCACCAGAGATGAGCTTTATAAAAATAATGGTGCTAGCTGGGCATGGTGGCTTGCACCTGTAATCCCAGCACTTTGGGAGGCCGA @BAHGDDDIKBKJ7HDJEKKHLLJIIJKGLHFJHHIHFFIEGCGCEILLHKJBBFKKIIIKIIKJLEJEKGJLFGFFFGIIJJJJFJGHGGIFHEDD?DB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR156632 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162875.4987821 83 17 2242 60 100M = 1996 -345 TATCACCAGAGATGAGCTTTATAAAAATAATGGTGCTAGCTGGGCATGGTGGCTTGCACCTGTAATCCCAGCACTTTGGGAGGCCGAGCTAGGAGGATCG DCDFHFIIHJIHIKJKKDIGIHGGHIJBIIDMKHKMIKKMIKLILHJLIJLJNKIKLFKJJGIHJHJHLJKLFLIHIJKJKIKHCHJIJFIHGIEFFE?A X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR243011.1711788 83 17 2265 60 100M = 1951 -413 AAAATAATGGTGCTAGCTGGGCATGGTGGCTTGCACCTGTAATCCCAGCACTTTGGGAGGCCGAGCTAGGAGGATCGTTTGAGTCCAGCAGTTTGAGACC ?2B=,;EB04@BJ=:D9.40=I;:497E12=JHA;9:00>JA12FB@1D;: X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243011 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:F@G@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR243079.862248 147 17 2274 60 100M = 1921 -452 GTGCTAGCTGGGCATGGTGGCTTGCACCTGTAATCCCAGCACTTTGGGAGGCCGAGCTAGGAGGATCGTTTGAGTCCAGCAGTTTGAGACCAGCCTGGCC CCC@?GEF4H:IE8G0JD269>G6H@/EFE6EGE?=DBII;;A2-G@;GJ7?8H;HGEJGLIFDF@>,H=ADDH:=EF;?F;@FFIG?EGGHF>FDCF9? X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243079 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162872.7043507 163 17 2276 60 100M = 2525 348 GCTAGCTGGGCATGGTGGCTTGCACCTGTAATCCCAGCACTTTGGGAGGCCGAGCTAGGAGGATCGTTTGAGTCCAGCAGTTTGAGACCAGCCTGGCCAA ECHBIJJJIJKHI?HILJJKGILGKLHIGJJJILGHKJEIMHHM?JJMJK5B*ILLINGILKJGKDFIDFEHILEJG=JMCEHAAIJ2JIJ@K8JFFG<( X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR245024.1210272 83 17 2280 60 100M = 1962 -417 GCTGGGCATGGTGGCTTGCACCTGTAATCCCAGCACTTTGGGAGGCCGAGCTAGGAGGATCGTTTGAGTCCAGCAGTTTGAGACCAGCCTGGCCAATACG 6FCDCGI:FF@@HGAI@IEE&<@:E@;GE;JJKF2GIJHHGJBH7I@F=IDAIH;BHFAG@BIFFGHBB@F?F@IE:HGEH@:CEDHBFF@FFEGCAH;GDFFGDGDBF?C;IFIFFGB?EAA>?I?;H8DAHHAH7GBA2DIH6HHDEBA>EFE=C X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243019 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@GBI +ERR242975.1004165 83 17 2290 60 100M = 1881 -508 GTGGCTTGCACCTGTAATCCCAGCACTTTGGGAGGCCGAGCTAGGAGGATCGTTTGAGTCCAGCAGTTTGAGACCAGCCTGGCCAATACGGCAAAACCCA DCCD;BFHHDHIGGF@D@IGIIIJEBEHGHIJJFJIBIHFLFIHJJHHGGAIHHFIKICIJKJHHGGGEIIIEIIIHHKGHHDIEGDDAGHGCCBEABD? X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR242975 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR243019.556608 83 17 2294 60 100M = 1851 -542 CTTGCACCTGTAATCCCAGCACTTTGGGAGGCCGAGCTAGGAGGATCGTTTGAGTCCAGCAGTTTGAGACCAGCCTGGCCAATACGGCAAAACCCAGTCT D?DEEBFEEECF9DHDIGJIEC;BHHAADIK;@KJIKFIFLHJKGD@HGHHFFJEGHCCJGGGGHKDH>GIFHIJGGHIFEFEGAHHHDDDFBEFGDDF? X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243019 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR013140.21458070 147 17 2301 29 108M = 2020 -388 CTGTAATCACAGCACTTTGGGAGGCGGAGCTAGGAGGATCGTTTGAGTCCAGCAGTTTGAGACCAGCCTGGCCAATACGGCAAAACCCAGTCTCTACAAAAAATACAA 920<'/7<1>?48/307$9C721:2$2A/9<226;<66=5?@?:6?AC=>=3DD?-?@E9BB@CBA@;?FDCDC:DEFCACC@FCCC?BBA=ABB@?: X0:i:1 X1:i:0 MD:Z:8C16C82 RG:Z:ERR013140 AM:i:29 NM:i:2 SM:i:29 MQ:i:29 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A@ +ERR162872.23671856 163 17 2311 60 100M = 2618 406 AGCACTTTGGGAGGCCGAGCTAGGAGGATCGTTTGAGTCCAGCAGTTTGAGACCAGCCTGGCCAATACGGCAAAACCCAGTCTCTACAAAAAATACAAAA BEGGFJGFLJIHLILKDGKKMIMKGMJHHLEHIGLJKJMKJMMIMHJHLIKKKLJLKMLKILLICHJKEJGFJJIGLLEMFKJLLHJJHIIHC?DFEFDD X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@GKKL +ERR245038.798432 147 17 2312 60 100M = 1958 -453 GCACTTTGGGAGGCCGAGCTAGGAGGATCGTTTGAGTCCAGCAGTTTGAGACCAGCCTGGCCAATACGGCAAAACCCAGTCTCTACAAAAAATACAAAAA BE?GE3FEGGDGE9>KI5HDFGIGI6:EAIG4IID9:GG@J;HHH@EIHJ?@F=JCFFHIJHDEE5>IKJFDDEFHIBHGHFGEEHEFECEGEEID@B?> X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR245038 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@FEHGG +ERR242971.738250 83 17 2315 60 100M = 1883 -531 CTTTGGGAGGCCGAGCTAGGAGGATCGTTTGAGTCCAGCAGTTTGAGACCAGCCTGGCCAATACGGCAAAACCCAGTCTCTACAAAAAATACAAAAAACA ECAAEGDGDHG=6DIKAIIJHHIE7@9FH;JHGHIEDKGJGHGFAEFEHJEIJJGJHIJFGECAHIFFFAEHIJIHEIGIDEHFFDEAECEHDCDBBEE? X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR242971 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A +ERR245024.420543 83 17 2317 60 100M = 1999 -417 TTGGGAGGCCGAGCTAGGAGGATCGTTTGAGTCCAGCAGTTTGAGACCAGCCTGGCCAATACGGCAAAACCCAGTCTCTACAAAAAATACAAAAAACAAC DCEEHEC?F?FEC:88FAA X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR245024 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:FE@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR242955.454193 83 17 2322 60 100M = 1904 -517 AGGCCGAGCTAGGAGGATCGTTTGAGTCCAGCAGTTTGAGACCAGCCTGGCCAATACGGCAAAACCCAGTCTCTACAAAAAATACAAAAAACAACTAGCC :D)8=CE3J??7E+:9I59BEI5H<@E8A?GD2HJHHFHFFHFJFCACAE+IEFD>HIHF=DJDFB?I8A@AFGDEIEFECDDICCHAEE;? X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR242955 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR243059.1325819 99 17 2332 60 100M = 2706 473 AGGAGGATCGTTTGAGTCCAGCAGTTTGAGACCAGCCTGGCCAATACGGCAAAACCCAGTCTCTACAAAAAATACAAAAAACAACTAGCCAGGCGTGGTG ?E@CH@E@G@ECBGGHEIGFIIFI?FCIE?CDBEIIHBI:@>F@F@D:IGHHGAJHJF9HFEE8GGC:0?2;2073>C@=@B7980@<8;:=82?2=?;3+>=D??34$1C#%*3<&4)67;39, X0:i:1 X1:i:0 MD:Z:83T7A16 RG:Z:ERR013140 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:ABC@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162875.5601349 163 17 2389 60 100M = 2710 420 AGTCTCTACAAAAAATACAAAAAACAACTAGCCAGGCGTGGTGGTGCACACCTGTAGTCCCAGCTACTCAGGAGGCTGAGGGGGAAGGACTGCTTGAGCC BFFHJIJHIIIIHIEIIJIJJIJHJJIJNIKLKHNKMEIMLGMKFILIJIKKMMIIMIMLLJNLLEJLKILIINHLLLALKKBIHILKJIKJHIFHFFFC X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@HH +ERR242983.1365156 83 17 2397 60 100M = 2021 -475 CAAAAAATACAAAAAACAACTAGCCAGGCGTGGTGGTGCACACCTGTAGTCCCAGCTACTCAGGAGGCTGAGGGGGAAGGACTGCTTGAGCCCAGGAGTT ;BABAEE>DJEFECBDBC:CE>A8C>C>7DBA=BEDDB4=9;:@=;@D@@=B@E.3?972<>6@8=>?1$0:95%5%*1=8;0%4<228% X0:i:1 X1:i:0 XC:i:88 MD:Z:88 RG:Z:ERR013140 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:EHG@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR243035.1445358 99 17 2405 60 100M = 2748 442 ACAAAAAACAACTAGCCAGGCGTGGTGGTGCACACCTGTAGTCCCAGCTACTCAGGAGGCTGAGGGGGAAGGACTGCTTGAGCCCAGGAGTTTGAGGCTG @CFEEFGFGGGIGEJIHHKFKADLGAJFELIEIHJIHJEELFJIIGKHIHGJJIKGFKJKJJGLHGJHHHLHHIEJJJEIFMKJIHJFFLFEEIAHGF@> X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243035 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162872.22794881 99 17 2407 60 100M = 2639 331 AAAAAACAACTAGCCAGGCGTGGTGGTGCACACCTGTAGTCCCAGCTACTCAGGAGGCTGAGGGGGAAGGACTGCTTGAGCCCAGGAGTTTGAGGCTGCT @BCCDBEFCFHAIGFHI@JAHK2>F:E;C>HIIKFF>CLCK;&+B2M4CLG=EHE+FH(+(F/'60.JB+),FB04 MD:Z:16T3G14C6T3G2G2G13G3G0A2C3G0A6G6G1G4 RG:Z:ERR162872 AM:i:29 NM:i:16 SM:i:29 MQ:i:29 XT:A:M BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162875.10770274 163 17 2415 60 100M = 2690 374 ACTAGCCAGGCGTGGTGGTGCACACCTGTAGTCCCAGCTACTCAGGAGGCTGAGGGGGAAGGACTGCTTGAGCCCAGGAGTTTGAGGCTGCTGTGAGCTG ECHFJHIHLIKEIKJIKIHLKIJIKJKLFIMGLIMKNILHJIJINKJL@KMLIMKJKKIKM?JJFMKLHKKLKJIKNKGLFJIIJMJHLKKJIGJEIGFB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162872.10955775 147 17 2419 60 100M = 2073 -445 GCCATGCGTGGTTGTGCACACCTGTAGTCCCAGCTACTCAGGAGGCTGAGGGGGAAGGACTGCTTGAGCCCAGGAGTTTGAGGCTGCTGTGAGCTGTGAT '9DA,J8DDL:>+JIILCKCKLJ6>LCJBCIKLAEHII;MJJKKEI?KJLKLELIGDMGLIJKHJLGDKKLJ6KLGIJIFJJHLIJKFIIFKJHHFEFAE X0:i:1 X1:i:0 MD:Z:4G7G87 RG:Z:ERR162872 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR242979.559120 147 17 2431 60 100M = 2075 -455 GGTGCACACCTGTAGTCCCAGCTACTCAGGAGGCTGAGGGGGAAGGACTGCTTGAGCCCAGGAGTTTGAGGCTGCTGTGAGCTGTGATCGCATCACTGCA @ADGG@H2ILDCEIH7HIHGKKEDJFGJIKJHIJGKHHIFHJEIJJCKJIJJGJGHJGIIGJIFIHHKIGKJGDJGGFJIHJGIFJGF@HIFEHCHEEF? X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR242979 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR243027.576419 99 17 2434 60 100M = 2778 443 GCACACCTGTAGTCCCAGCTACTCAGGAGGCTGAGGGGGAAGGACTGCTTGAGCCCAGGAGTTTGAGGCTGCTGTGAGCTGTGATCGCATCACTGCATTC >DB@DDFIEFD;BH;?BHFEF?:JECGBHE1;9EIK.F1:G-DAH9I,.=>EF9D@E X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243027 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@G +ERR242999.1001077 147 17 2438 60 100M = 2110 -427 ACCTGTAGTCCCAGCTACTCAGGAGGCTGAGGGGGAAGGACTGCTTGAGCCCAGGAGTTTGAGGCTGCTGTGAGCTGTGATCGCATCACTGCATTCCAGC 5CJDGDHGCIHIBJJDEGEJIJHKHJLIIIHJHGFGHHJEMJBKHIHIKHNKDGIKIIFIIJIJJIJKHIFKGKKHIGJGHBIIFGJEHGIIDFGDGFCA X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR242999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C +ERR013140.30331713 83 17 2444 60 108M = 2120 -431 AGTCCCAGCTACTCAGGAGGCTGAGGGGGAAGGACTGCTTGAGCCCAGGAGTTTGAGGCTGCTGTGAGCTGTGATCGCATCACTGCATTCCAGCCCGGTGACAGAGTG 938:(A@??<8>>>GBGIEFFIGDHLGKJDLIKGFJIGKLKJKCIEJ@LJDIELKLLKJLJFLHKKLJIKGKKHK@GIGKIDIJIHGJJIHKIIF?JEIHFGIHFAC@ X0:i:1 X1:i:0 MD:Z:108 RG:Z:ERR013140 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162872.474429 99 17 2447 60 100M = 2812 464 CCCAGCTACTCAGGAGGCTGAGGGGGAAGGACTGCTTGAGCCCAGGAGTTTGAGGCTGCTGTGAGCTGTGATCGCATCACTGCATTCCAGCCCGGTGACA BAD5=FHEGHFFHIBC;HFJGKD1JIFGHIHJKJIKGKGK2F?BMHE9,HEDK9HFKJFELHJ2BJL.0@FHC1K3DE3ELE=GGBEBIFB6BA9CE9?1 X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162872.12579188 83 17 2456 60 100M = 2147 -408 TCAGGAGGCTGAGGGGGAAGGACTGCTTGAGCCCAGGAGTTTGAGGCTGCTGTGAGCTGTGATCGCATCACTGCATTCCAGCCCGGTGACAGAGTGAGTC ;DGGIIGJKILJGKJJHGKKJHM?JLEIKMMKGLMLMLKIGJMKJLMELIIJIMIKMIHIJJHEKKGILHKGLKIIJIKKIJJCJIHIGIIHIFFFHDCB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR243063.1642219 1171 17 2462 60 100M = 2084 -477 GGCTGAGGGGGAAGGACTGCTTGAGCCCAGGAGTTTGAGGCTGCTGTGAGCTGTGATCGCATCACTGCATTCCAGCCCGGTGACAGAGTGAGTCACTGTC DF8AH9?GHHCGCHJBKAIK>HJDC=HCIIJFGGAEJGIJKCADDIAI:IC8H9HDB?IG@GC=;87GAHB=G>H;2@GEHIFGHBGGFFFFDGDHDDB: X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243063 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:BA@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR243063.246578 147 17 2462 60 100M = 2084 -477 GGCTGAGGGGGAAGGACTGCTTGAGCCCAGGAGTTTGAGGCTGCTGTGAGCTGTGATCGCATCACTGCATTCCAGCCCGGTGACAGAGTGAGTCACTGTC A@G;HFFFFF9CHHHFDEE@3HJHI/HIIDJJH?DGDFIJJHIKEIGIHDKEGCCDE?EGEGHBK?IFFABEGJCH2@GEHIEGHHGGF>HFGDDB? X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243063 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162872.7043507 83 17 2525 60 100M = 2276 -348 ACTGCATTCCAGCCCGGTGACAGAGTGAGTCACTGTCTCGAAAAAGAAAGGAAGAAATAAAGAAAACAAATAAAAATAATAGTGCAGACAAAAGGCCTTG KCJIE;J@>LIKJLLIJMKIFLHKJLEJIEKHHBHKKIGLLKILMIGKDHGMMGGHGHGGJHHGHHJHDHFLIIJJGJFIFEEIGGBHCDB X0:i:1 X1:i:0 MD:Z:39A60 RG:Z:ERR162872 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR013140.20581831 147 17 2526 60 108M = 2212 -421 CTGCATTCCAGCCCGGTGACAGAGTGAGTCACTGTCTCAAAAAAGAAAGGAAGAAATAAAGAAAACAAATAAAAATAATAGTGCAGACAAAAGGCCTTGACCCATCTA @EBBBAC@DG@C@6FCHEEDEBH=B>EECCFDGBCC@FFFHGGKDFGLEKFKDFFI@FFHFFFEIJFFIAEEEEHDDHHGGFJIIIHIDDDIIIJJHGFEHGCBEFB: X0:i:1 X1:i:0 MD:Z:108 RG:Z:ERR013140 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR243007.1719649 147 17 2533 60 100M = 2188 -444 CCAGCCCGGTGACAGAGTGAGTCACTGTCTCGAAAAAGAAAGGAAGAAATAAAGAAAACAAATAAAAATAATAGTGCAGACAAAAGGCCTTGACCCATCT DEFHGFAGHHJDJGGJIHKIIFH>LHHF<9CFEGFEJKFEJJJHKIFBGFFHIKFHEEIFGGFEEFEICDHFJHHJIIJFJEFEJIIEJFGIEEEIEDF@ X0:i:1 X1:i:0 MD:Z:31A68 RG:Z:ERR243007 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:B@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR156632.5990783 163 17 2544 60 100M = 2843 398 ACAGAGTGAGTCACTGTCTCGAAAAAGAAAGGAAGAAATAAAGAAAACAAATAAAAATAATAGTGCAGACAAAAGGCCTTGACCCATCTAGCTTTGGCCC BCFGFHFHGGFIGHJIGJIIBIHHIILGIFLJGIKIIIFIEGHJIIKIHIJHJIJJJIIIHGLHMCJMKJJHIILFKKLHLKJJ?FHLKHLIKF=D=GED X0:i:1 X1:i:0 MD:Z:20A79 RG:Z:ERR156632 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@BCD +ERR243019.804639 83 17 2558 60 100M = 2190 -467 TGTCTCAAAAAAGAAAGGAAGAAATAAAGAAAACAAATAAAAATAATAGTGCAGACAAAAGGCCTTGACCCATCTAGCTTTGGCCCTCAGCATCAACCGC DEDIAFDFFFCHJCBCGKDJMFGGAFHCLFDDEKFGH@FGGHHFEIDIHIICIJCJGFFIGJGJGCK@HGIGFHEIIHEGGHIGGJGHIHIFFCBEA>D? X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243019 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162872.17163139 163 17 2564 60 100M = 2828 363 AAAAAAGAAAGGAAGAAATAAAGAAAACAAATAAAAATAATAGTGCAGACAAAAGGCCTTGACCCATCTAGCTTTGGCCCTCAGCATCAACCGCTAGATA EACFFGJHHIHI3IMIGIJI>>GJIJKKJ?JKBJIJHIJIHIMHMJJMKJJAFKMJKMNHMKJM=GKMKINLLIHI>LKGKMJIKGIHJIJGCIJ?HFD- X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:GCDEDB@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR243019.1623189 83 17 2569 60 100M = 2285 -383 AGAAAGGAAGAAATAAAGAAAACAAATAAAAATAATAGTGCAGACAAAAGGCCTTGACCCATCTAGCTTTGGCCCTCAGCATCAACCGCTAGATACGTCC EA?C?F>=D@;FBFBGFD?B?AH8H?6@G4JDIIGEFFF:C9@@CDGHCCE X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243019 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C +ERR243091.852212 163 17 2575 60 100M = 2967 491 GAAGAAATAAAGAAAACAAATAAAAATAATAGTGCAGACAAAAGGCCTTGACCCATCTAGCTTTGGCCCTCAGCATCAACCGCTAGATACGTCCCTCCCT ACDHFEFGDGEJGDIHHHDIHDEGIHCFHHD7=:@<&I4L;C?/AJ9JK>J2DHKAK5,H29=,=0,E9?H.GKJGE78&,6A X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR156632 AM:i:29 NM:i:0 SM:i:29 MQ:i:29 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162875.20693133 99 17 2588 60 100M = 2892 403 AAACAAATAAAAATAATAGTGCAGACAAAAGGCCTTGACCCATCTAGCTTTGGCCCTCAGCATCAACCGCTAGATACGTCCCTCCCTTTCTTCTGGGGCA A:CEECDFEDGGHGF@GE<=D2F?BF?>HICFH7EJIKHHCIGFEF@BJHFKJGEHDCLGEHHIFGGHHIGIFDKDIJGEJJHJGJHFKHFDF>JEE?GDCEB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243007 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR156632.12418699 163 17 2634 60 100M = 2962 427 GCTTTGGCCCTCAGCATCAACCGCTAGATACGTCCCTCCCTTTCTTCTGGGGCACAGGTCACACTCTCTTCCAGGTCTAGGATGCAGCTGAGGGGTGCCC BDGBCGEHGHHIGJGHFJHIIKDIHHIGIIICHKJKFKLKKF@KMDKJJKJJLIEHMK=KIJJEMMJKIHLJJKJILKJJKHHJJJFHKIIJAIGFH9E> X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR156632 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@JD +ERR013140.12984374 147 17 2636 60 108M = 2382 -361 TTTGGCCCTCAGCATCAACCGCTAGATACGTCCCTCCCTTTCTTCTGGGGCACAGGTCACACTCTCTTCCAGGTCTAGGATGCAGCTGAGGGGTGCCCCTCTTACCAT '??98:CD@B<CDI@CCF;>DEFCACDD?@BDCFBFFEAB?>BDGACDDECDCEDFAADDFBB@CHFJICIJIEECDFEADGDHHCAJBDBDA>CA@9 X0:i:1 X1:i:0 MD:Z:108 RG:Z:ERR013140 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162872.22794881 147 17 2639 60 100M = 2407 -331 GGCCCTCAGCATCAACCGCTAGATACGTCCCTCCCTTTCTTCTGGGGCACAGGTCACACTCTCTTCCAGGTCTAGGATGCAGCTGAGGGGTGCCCCTCTT 6?.97*GGD:-:810C?IIEJKBCFDJ>HCFFGEIFIGJ:JCJJE@:2>@2+4B>E>BBDDDAD@DE:=D9CGD;'A X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B +ERR242943.312088 163 17 2694 60 100M = 3037 442 ACACTCTCTTCCAGGTCTAGGATGCAGCTGAGGGGTGCCCCTCTTACCATCTAATCTGTGCCCTTATTTCCTCTGCTTTAGTGAGGAAGAGGCCCCTGGT ABEEHHIIGEIHGL9FIIEMEFGKJHJIGKEJGEHDKJIDFDIHEGIGFGLKEIGHJJEGJIACGDHGFJHCHIIIIFDELGIF9HFD;EKFHFFEEFC. X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR242943 AM:i:25 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162875.5443750 99 17 2699 60 100M = 3006 406 CTCTTCCAGGTCTAGGATGCAGCTGAGGGGTGCCCCTCTTACCATCTAATCTGTGCCCTTATTTCCTCTGCTTTAGTGAGGAAGAGGCCCCTGGTCCATG AAFG?FE9<3/IDDJIHBDEIL5;JHGH:/>LJHD?JH@F*CJ8H@.GII>IHB:EJL82B81I7?BA?E;8H>;J:CHK@2(HDH.7C/47.48A(+8; X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:25 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR243059.1325819 147 17 2706 60 100M = 2332 -473 AGGTCTAGGATGCAGCTGAGGGGTGCCCCTCTTACCATCTAATCTGTGCCCTTATTTCCTCTGCTTTAGTGAGGAAGAGGCCCCTGGTCCATGAAGGGGC 2DDDGDFFH?DIIIGHGJAHGJJ;JJ8HJ>IIBBIJIIJE@GGJHIGIHI>FFDJIEHJFKHJJIH@IHFJIIKFIGICHIHBHHHGFHJFGHDHFFAB@ X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243059 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B +ERR162875.5601349 83 17 2710 60 100M = 2389 -420 CTAGGATGCAGCTGAGGGGTGCCCCTCTTACCATCTAATCTGTGCCCTTATTTCCTCTGCTTTAGTGAGGAAGAGGCCCCTGGTCCATGAAGGGGCCTTT D@HHHEGEJJJKGKDKJLIJKIJHMGLIIIKKIJMIIJJMIJKJKKOHHGJI@MMIHJIJIGILKHKLKJGLKKKKKJKLIKIHJJGHIEIHGFGDHCBA X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A +ERR243019.480835 99 17 2711 60 100M = 3135 523 TAGGATGCAGCTGAGGGGTGCCCCTCTTACCATCTAATCTGTGCCCTTATTTCCTCTGCTTTAGTGAGGAAGAGGCCCCTGGTCCATGAAGGGGCCTTTC ??GADDHDFIHIHFJGDDEHIHHGHIHEFHGDEGF?GEHGJEEGHGGFFBFEEFEIIJHH@FFKEIHKIEHHGKHGBIHIHFFIHGHKCGKDHFFEFBCD X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243019 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162872.13634813 147 17 2713 29 100M = 2414 -398 GGATGCAGCTGAGGGGTGCCCCTTTTACCATCTAATCTGTGCCATTATTTCCTCTGCTTTAGTGAGGAAGAGGCCCCTGGTCCATGAAGGGGCCTTTCAG F,7?1D.JK>H@80DJA3.K6LJ%7IHJH85ADIDFB8K8300(66AAGK;;:EEE X0:i:1 X1:i:0 MD:Z:23C19C56 RG:Z:ERR162872 AM:i:29 NM:i:2 SM:i:29 MQ:i:29 XT:A:U BQ:Z:D@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B +ERR245049.1543898 99 17 2735 60 100M = 3077 441 TCTTACCATCTAATCTGTGCCCTTATTTCCTCTGCTTTAGTGAGGAAGAGGCCCCTGGTCCATGAAGGGGCCTTTCAGAGACGGGGACCCCTGAGGAGCC ?DFABEFFFHHEGGJHIHJIHHHEFGEEJHHIHJIJEF@IGGGJFFFKHKCFHIIIKFFJGHHJIHEMAJJGIGAKIJHGFE5EII76IDG>;?FEAHGIIFFGFE@? X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243035 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR243027.576419 147 17 2778 60 100M = 2434 -443 GGAAGAGGCCCCTGGTCCATGAAGGGGCCTTTCAGAGACGGGGCCCCCTGAGGAGCCCCGAGCAGCAGCCGTCGTGTCTCACCCAGGGTGTCTGAAACAG :DCC@>DCC1HBEEBE=>/;:4;>*E?FBGB-IGEC@>BIHH9#F0H+2?@FCI4A>HAGHBEDFIJDHDEDDDJGI>BAECA X0:i:1 X1:i:0 MD:Z:43A56 RG:Z:ERR243027 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162875.1633327 83 17 2786 60 100M = 2618 -267 CCCCTGGTCCATGAAGGGGCCTTTCAGAGACGGGGACCCCTGAGGAGCCCCGAGCAGCAGCCGTCGTGTCTCACCCAGGGTGTCTGAAACAGATGTGGAG =DBCJ@DHEHGJHBIEHHFA':'>:;BHHLKJKJ6=BH7FII->G9DF5?.;*7A0?== X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243067 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:BB@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B +ERR162872.17163139 83 17 2828 60 100M = 2564 -363 AGGAGCCCCGAGCAGCAGCCGTCGTGTCTCACCCAGGGTGTCTGAAACAGATGTGGAGGTCTCGGGTGAGGCGTGGCTCAGATACAGGGAGTGGCCCACA 4CGHB?HDB8CJDKHLJJJBJHDJHJJMIKAFIEMLKJJJIMJKGIILLMJFJIKJMGJIMGDIKKJHLLHEGFKJLHGKKHGGKJIII?EEGGCCGDEB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162872.20228886 99 17 2837 60 100M = 3084 346 GAGCAGCAGCCGTCGTGTCTCACCCAGGGTGTCTGAAACAGATGTGGAGGTCTCGGGTGAGGAGTGGCTCAGATACAGGGAGGGGCCCACAGCTCGGCCT @CG8DHF:=7?5GBAGDGAL9I9JB,BIHHH=5B,8;4M./MK7E/.GL(B.*.88J1FBFJA6CDB;H57L&K:)(GI1B405B.-17) X0:i:1 X1:i:0 MD:Z:62C19T17 RG:Z:ERR162872 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR156632.5990783 83 17 2843 60 100M = 2544 -398 CAGCCGTCGTGTCTCACCCAGGGTGTCTGAAACAGATGTGGAGGTCTCGGGTGAGGCGTGGCTCAGATACAGGGAGTGGCCCACAGCTCGGCCTGTCTTT DFEEAFH@HGJHLHKFKJLJLLJKKIMKJFHGIJLIEJJJLGLKDNHCKJKJLKLLEAILHLHJHKIFHLLKLJLEHLKKKKHJJKKICJJGIGEGIEBD X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR156632 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D +ERR162875.26247502 83 17 2858 60 100M = 2581 -376 ACCCAGGGTGTCTGAAACAGATGTGGAGGTCTCGGGTGAGGCGTGGCTCAGATACAGGGAGTGGCCCACAGCTCGGCCTGTCTTTGAAAGGCCACGTGAC HGGAGICIHGJJEHGJ@E>?ICJAJ@EIIDBIHLBF@IHKI2DKF=EIHKFIHLJDK=CHHDDJ@G:>@C?F;,CGI8G;HDHBJ:BJDGHJ>LIKA*@GIIF@BF::FF1JJBLCJDKGBJJJIFFJIFIIJDJ:IDJJHJGDFB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:DE@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162875.13732136 163 17 2900 60 100M = 3298 497 GTGGCTCAGATACAGGGAGTGGCCCACAGCTCGGCCTGTCTTTGAAAGGCCACGTGACCTGGCCCACGGCTGGCAGGTGGGACCCAGCTGCAGGGGTCCA DDHBIJIHLHIHJJLIJIMILKKJLGJ:JKLMBKLJLM?AHFJGIGALJKLHIEIFIEHC94ACB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR245038 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D +ERR162872.24480599 99 17 2922 60 100M = 3229 406 CCCACAGCTCGGCCTGTCTTTGAAAGGCCACGTGACCTGGCCCACGGCTGGCAGGTGGGACCCAGCTGCAGGGGTCCAGCAGCACCCACAGCAGCCACCG BADEEEIHHFADFGJKEJHHGCHEBGJHIIECGFKJLLIBJFJGE<.KFA;JHMHBGCFCJMKC7;LKI49J@>1KD2G)BC1AC>KAHF77+4HC3:@$ X0:i:1 X1:i:0 MD:Z:99T0 RG:Z:ERR162872 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR243007.1511398 147 17 2951 60 100M = 2622 -428 ACGTGACCTGGCCCACGGCTGGCAGGTGGGACCCAGCTGCAGGGGTCCAGCAGCACCCACAGCAGCCACCTGTGGCAGGGAGGAGCTTGTGGTACAGTGG -;EDIBBIHHFEEHC?DIJ:IIHJIHCHJB2G:HIELHJIJHI?HCHEIDJGDJFIHHEFGIJIIHIEIIHJGHIJHHHJIIIHHKIHHHGGDEHFFE>@ X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243007 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR243039.1477734 147 17 2955 60 100M = 2595 -459 GACCTGGCCCACGGCTGGCAGGTGGGACCCAGCTGCAGGGGTCCAGCAGCACCCACAGCAGCCACCTGTGGCAGGGAGGAGCTTGTGGTACAGTGGACAG @BCHBEAED@C8EIH7EJICIIIGFH0GGKJIJGLGAEIIGGFHEGDA X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243039 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C +ERR156632.12418699 83 17 2962 60 100M = 2634 -427 CCCACGGCTGGCAGGTGGGACCCAGCTGCAGGGGTCCAGCAGCACCCACAGCAGCCACCTGTGGCAGGGAGGAGCTTGTGGTACAGTGGACAGGCCCTGC 6:FFAGIJHKKLMLJKLKL;9KLIGIGLJIJKK>JKLFDMMKLHJKFHKLLLJMJLHLMFJKKLNKMKLLMKNJ>JIKJIJHH5KIHFLH=JJJIHIECD X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR156632 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@F +ERR243091.852212 83 17 2967 60 100M = 2575 -491 GGCTGGCAGGTGGGACCCAGCTGCAGGGGTCCAGCAGCACCCACAGCAGCCACCTGTGGCAGGGAGGAGCTTGTGGTACAGTGGACAGGCCCTGCCCAGA AFBAE<@GIG@H7I@5=?HCIEFJDHG?DBFAJDHJIFE0IDCFJIJFI@HAGJIGDCHIHGGJFCEGIEFHHGFHE?G>GGBGDIEFG=B>GHA=FFE? X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243091 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR243043.1629476 163 17 2977 29 100M = 3421 543 TGGGACCCAGCTGCAGGGGTCCAGCAGCACCCACAGCAGCCACCTGTGGCAGGGAGGAGCTTGTGGTACAGTGGACAGGCCCTGCCCAGATGGCCCCCCC ?E?>CEEFDIGHHFGG>FFGJEGJGFJHFHGECHG=FGJHHFGIFI@K>IEHFC8DAGLIF>JBHE:AJHH:I:G*>BCDCDB8GHF6.5@FF10;@E92 X0:i:1 X1:i:0 MD:Z:99G0 RG:Z:ERR243043 AM:i:29 NM:i:1 SM:i:29 MQ:i:29 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C@BOU[PL +ERR156632.1508798 83 17 3006 29 1S4M1D95M = 2587 -518 CCCCAAGCAGCAGCCGGGGGCAGGGAGGAGCTTGTGGTACAGTGGACAGGCCCTCCCCAGATGCCCCCCCGCCTGCCTGTGGAAGTTGACCAGACCATCT <'&*(-+/?*88'-%%(((+KB/N.G)9.5E39>/;,FBHLI?CKH=BJ?FEE==DA MD:Z:4^C6C0A2T1T36G8G36 RG:Z:ERR156632 AM:i:29 NM:i:7 SM:i:29 MQ:i:29 XT:A:M BQ:Z:@FEIG@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162875.5443750 147 17 3006 60 100M = 2699 -406 CCCACAGCCCCCACCTGGGGCAGGGAGGAGCTTGGGGTACAGTGCACAGGCCCTGCCCAGATGGCCCCCCGCCTGCCTGTGGAAGTTGACCAGACCATCT @6F1-8/B%#K/,H/4A3EA9@KI7.1F049E82))G61;/,-H*C<)9*JB;.*E=;;9/.E8IGG>H*K3GJ6F256:D6:AGJ6H:CA;L5KK;@5IGBKB;:>5KHJLKDGHMDLJJKIJJLGLJJJLIKKKKHIKHIKIHHJGIHDD X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR242943.897194 147 17 3015 60 100M = 2661 -453 GCCACCTGTGGCAGGGAGGAGCTTGTGGTACAGTGGACAGGCCCTGCCCAGATGGCCCCCCGCCTGCCTGTGGAAGTTGACCAGACCATCTGTCACAGCA +EF0D..G8E:D9FIA?GB;3;ECG:HG@2DBJ/F;;;CG?GFC;7H@*DFA=I+FGGJE?IILHIGJGKIGJEJIIGHEFJIJFHKGGJGFGHEIGEEA X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR242943 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162872.25542568 99 17 3017 60 100M = 3110 192 CACCTGTGGCAGGGAGGAGCTTGTGGTACAGTGGACAGGCCCTGCCCAGATGGCCCCCCGCCTGCCTGTGGAAGTTGACCAGACCATCTGTCACAGCAGG BDDCHHFFEEGJHBEII0KGKEGEECF?D4?H9GGHH@:I;EFHB=GBI6GGE<+AIEGJBDI:9IGDJAKEHEJHCBIGHJDGHGFJFHIGHFAIFFJGHGIEIGHHGFEBBD? X0:i:1 X1:i:0 MD:Z:62T37 RG:Z:ERR242971 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR243039.71589 147 17 3030 60 100M = 2654 -475 GAGCGGCTTGGGGTCCAGGGGACAGGCCCTGCCCAGATGGCCCCCCGCCTGCCTGTGGAAGTTGACCAGACCATCTGTCACAGCAGGTAAGACTCTGCTT .2*D-E;*DH>GCHF

,+@3IEA;IBAJKHHDKFHJIKDJJDFKI;IKIIAIHIKIIBKGLJKLJIJHHIGGJGKIDKEHHJGHGHIEEBAGHB X0:i:1 X1:i:0 MD:Z:9A90 RG:Z:ERR162872 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR243063.161207 99 17 3057 60 100M = 3124 166 CCTGCCCAGATGGCCCCCCGCCTGCCTGTGGAAGTTGACCAGACCATCTGTCACAGCAGGTAAGACTCTGCTTTCTGGGCAACCCAGCAGGTGACCCTGG AAFHGFFFIFGIGIGFHHHAJHIHGHIJFKGFHICDJGHIGMFHGBIJEKEHIIFJJHLHBGIIGJJIIJKHABIIKHJHFFHIHIMIGJEDJFEFFBFB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243063 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:CC@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A@ +ERR243007.788439 147 17 3067 60 100M = 2789 -377 TGGCCCCCCGCCTGCCTGTGGAAGTTGACCAGACCATCTGTCACAGCAGGTAAGACTCTGCTTTCTGGGCAACCCAGCAGGTGACCCTGGAATTCCTGTC >=4EGDHEACGIHKIKHHHHJKGIIHJCIIIJHIJG;LIHHKGLKIJJHIEJKLFMGJGJKGGGJGHIJJFEFHJJIJHHIHIEIHKHHJEFFFGIFEC@ X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243007 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B +ERR245049.1543898 147 17 3077 60 100M = 2735 -441 CCTGCCTGTGGAAGTTGACCAGACCATCTGTCACAGCAGGTAAGACTCTGCTTTCTGGGCAACCCAGCAGGTGACCCTGGAATTCCTGTCCATCTGGCAG CF@GAHEHDEJFHHGHJFJKHHG=KFDKHHIIFKIKEHACHDJJFJEJBJKIIHJHHHJIFDFJIGGJIHIFJHAIKGIJFHHFIKIHGHIGFIGGHGDA X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR245049 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:AA@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C +ERR243031.650799 99 17 3080 60 100M = 3507 526 GCCTGTGGAAGTTGACCAGACCATCTGTCACAGCAGGTAAGACTCTGCTTTCTGGGCAACCCAGCAGGTGACCCTGGAATTCCTGTCCATCTGGCAGGTG ?DBFHDH?DFIBCIEGEGDFHAGCIIIE=GHGGFHIDD@IHCHHJDFEADDE>C8EGG6:JIEL?GG8BI@G2EGIHGI=GIHEIDKJDGJIFEFC@>BD X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243031 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@F +ERR162872.20228886 147 17 3084 60 100M = 2837 -346 GTGGAAGTTGGCCAGACCATCTGTCACAGCAGGTAAGACTCTGCTTTCTGGGCAACCCAGCAGGTGACCCTGGAATTCCTGTCCATCTGGCAGGTGGGCA 6+0GEG;HD?)'@8K0/GJ89>B=:GILFGD3HB<LG>GC5GBGD?7CIEECAHADBFDCBDAKFGEEGFDEFC@AED?DDDD'>>>CKGBF?HE@EB@CF>FGDED>@ X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243051 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162875.1328730 99 17 3121 60 100M = 3494 472 ACTCTGCTTTCTGGGCAACCCAGCAGGTGACCCTGGAATTCCTGTCCATCTGGCAGGTGGGCATTGAAACTGGTTTAAAAATGTCACACCATAGGCCGGG BDHEHHGIDEIHHAHJDDEFIHIDAKI<<5IJ;JKEB3F=CFCJHIJHEJIKCLFLBECD2GIEH5A4FCH53= X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR243063.161207 147 17 3124 60 100M = 3057 -166 CTGCTTTCTGGGCAACCCAGCAGGTGACCCTGGAATTCCTGTCCATCTGGCAGGTGGGCATTGAAACTGGTTTAAAAATGTCACACCATAGGCCGGGCAC EDFGEDEJGH@HIBCMHKJIICHGGIFIGKDGIGIFGCKGIHGIHFJCHIJJHHFICJIGGDJDFDKGHIEGEFFFFGCHEIEIEGHDEGGGC?EEEFC? X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243063 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR243027.47729 99 17 3134 60 100M = 3547 512 GGCAACCCAGCAGGTGACCCTGGAATTCCTGTCCATCTGGCAGGTGGGCATTGAAACTGGTTTAAAAATGTCACACCATAGGCCGGGCACAGTGGCTCAC >?FEDFFGGIHGJGAJEHHFHIHFIGFJHHJEJIDHKCIIJFKIFJHFJBGCIEFIHIGJGFEAGGJFFLHJHGAIIBIFKGIEAGG?IIFFDHCFDE9C X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243027 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR243019.480835 147 17 3135 60 100M = 2711 -523 GCAACCCAGCAGGTGACCCTGGAATTCCTGTCCATCTGGCAGGTGGGCATTGAAACTGGTTTAAAAATGTCACACCATAGGCCGGGCACAGTGGCTCACG EFB;GBGHGKIHHFJBHEBIGJGHHHJLIG?BFGGDEHGB@:H?>?=H@CGHEBJDHDFCEEGH98AJHB?GAGEEJ9EDGHBE736? X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR245041 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162875.19273677 99 17 3143 29 99M1S = 3488 443 GCAGGTGACCCTGGAAATCCAGTCCAACTGGCAGGAGGGCATTGAAACTGGCTTAACAATAACAAACCATAGGCCCAGCACAGTGGCTCACTCCTGTAAA A.<='.HF8B@>I45)D3I.,8&;J;(174HBHEE). XC:i:99 MD:Z:16T3T5T8T15T4A3G0T2C10G0G14G7 RG:Z:ERR162875 AM:i:29 NM:i:12 SM:i:29 MQ:i:29 XT:A:M BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@Q@@ +ERR243031.386955 163 17 3144 60 100M = 3511 466 CAGGTGACCCTGGAATTCCTGTCCATCTGGCAGGTGGGCATTGAAACTGGTTTAAAAATGTCACACCATAGGCCGGGCACAGTGGCTCACGCCTGTAATC ADHDDHGGGGIKIGEGDIGHJEIGGHKIJDJHKIBLIGIHHFKHFIHJJGDGEDHHEHHJCJBDFDHIEDGGBH:JCGGIHIEJHEGEFHAGC=D@C3=B X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243031 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D +ERR243091.881299 163 17 3174 60 100M = 3491 416 CAGGTGGGCATTGAAACTGGTTTAAAAATGTCACACCATAGGCCGGGCACAGTGGCTCACGCCTGTAATCCCAGCCCTTTGGGAGGCCAGGGTGGGTGGA ACHCFJFGHGEFJFIHHJIJGEFEIHHFDJDKHIGHHGGEKIIGAJJIHJHNCKHJJJHJCKIHJAGJHJIHGKJGHJEEEIGFJIIHHHDGDHEDBGEA X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243091 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR243067.1030440 147 17 3191 60 100M = 2824 -466 TGGTTTAAAAATGTCACACCATAGGCCGGGCACAGTGGCTCACGCCTGTAATCCCAGCCCTTTGGGAGGCCAGGGTGGGTGGATCACTTGAGGTCAGGAG @?BD=<9$=>-74&CI@7FIE8AHA5E>HFIDFKJ8H0BCDHJFGHHH=ACHEGGDHEDD@ X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243067 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162872.18600710 163 17 3209 60 100M = 3375 265 CCATAGGCCGGGCACAGTGGCTCACGCCTGTAATCCCAGCCCTTTGGGAGGCCAGGGTGGGTGGATCACTTGAGGTCAGGAGTTCAAGACCAGCCTGGCC EBFFFKIJJCIIKIHILILKLLLJIDKJGHIIGJLLJCKKLKLGIKGKKLKLLIKJLEKIL2LJKBLKHLIHJIJIMJLKILEHLIFLJILFGJJEHGF3 X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:C@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A@ +ERR156632.13236661 147 17 3218 60 100M = 2887 -430 GGGCACAGTGGCTCACGCCTGTAATCCCAGCCCTTTGGGAGGCCAGGGTGGGTGGATCACTTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGTG >ECDFFGGBKJKGK@CLKJHJJF;F< X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162872.24480599 147 17 3229 60 100M = 2922 -406 CTCACGCCTGTAATCCCAGCCCTTTGGGAGGCCAGGGTGGGTGGATCACTTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGTGAAACCCCGTCT B7H:=HFGAGBHICJCLLHGEHK>?KHKIMHI:MEDGFLBIHIEIJLJM=IGLLJFHLKIKIJHLHFIHKLJIEKIKK+KHHIJILJAJHGHDIAAFEED X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR242963.1107552 1187 17 3234 60 100M = 3565 430 GCCTGTAATCCCAGCCCTTTGGGAGGCCAGGGTGGGTGGATCACTTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGTGAAACCCCGTCTACTAA @ABGHECGEFGGEJHIHHFFIHGDKGKGHLHHEHHHDJHEHIHGLIKFKGCJHK=ELFEKHGKFHIGLJJKKHJGGIGIGMKEGHHHHFIG?BGF?EF?C X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR242963 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@AH +ERR242963.383553 163 17 3234 60 100M = 3565 430 GCCTGTAATCCCAGCCCTTTGGGAGGCCAGGGTGGGTGGATCACTTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGTGAAACCCCGTCTACTAA @DEGGEDGGJGGGKJIHIFFIHGDKHKGHLHHEKHHDJHHHIHIJEHHKGEJJKFGLFEKHGGIHIILIFKKJJGGDJHGIKDGGGGIFIG?EIF?DEAC X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR242963 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@CH +ERR162875.6771266 99 17 3240 60 100M = 3423 282 AATCCCAGCCCTTTGGGAGGCCAGGGTGGGTGGATCACTTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGTGAAACCCCGTCTACTAAAAATAC ABEEDEFIHFHIGFHGHHKHKKHIIG>JIJGKHIHLIJIHJIMKHLKNJFN:HLHJMJJMFLKKILKMMK?GIGIJHI@GFGJELEAHFIFKGGFBFCC? X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR243015.596677 83 17 3240 60 100M = 2861 -478 AATCGCAGCCCTTTGGGAGGCCAGGGTGGGTGGATCACTTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGTGAAACCCCGTCTACTAAAAATAC 5@C>*8FI6D:EBAG:GHD>F8;FK;G>FIIJH:0C<9IIAAIF>J>JIFJEE?CHHJD@FCGHIFJ@CA;G@:GFG@EIDCCCBC@B? X0:i:1 X1:i:0 MD:Z:4C95 RG:Z:ERR243015 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR245032.287858 83 17 3258 60 100M = 2905 -452 GGCCAGGGTGGGTGGATCACTTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGTGAAACCCCGTCTACTAAAAATACAAAAATTAGCCTGGCGTG CCDGCEFFHIAJGGFG>JCKHFKIIJGLGFIHH?HJFIJ>HHHHDLIJKGKEFMHFJKHJEGEIIGAIHLEEKDGEFGG@DJEEEGGGFHHFJGGG@ED@ X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR245032 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B +ERR245038.1772750 83 17 3261 60 100M = 2917 -443 CAGGGTGGGTGGATCACTTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGTGAAACCCCGTCTACTAAAAATACAAAAATTAGCCTGGCGTGGTG EEDEFEDFIBGGBFK;DGHHGIIGFIJCHIGGGEIG>IJIIHJGHIFHFEJHGHIFJECDGHHAIGIEGJCEGEEGEEIDFEFGEEIHCIFFH@EEBDC> X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR245038 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR156632.4053670 147 17 3280 60 100M = 3038 -341 GAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGTGAAACCCCGTCTACTAAAAATACAAAAATTAGCCTGGCGTGGTGGCGCATGCCTGTAATCCCA DCEFGFCJIHCIGIFKL@LKKLKKEKL=LHHIIJMKHLFGHKKKCJIMHGMGGHGIJIGMHHHGHIHLHKMIKJCIHKIHKJCHJGGIFJFFFCFFBAFB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR156632 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162875.18994301 163 17 3289 60 100M = 3627 437 AGTTCAAGACCAGCCTGGCCAACATGGTGAAACCCCGTCTACTAAAAATACAAAAATTAGCCTGGCGTGGTGGCGCATGCCTGTAATCCCAGCTACTTGG EFFEIGGKHIKHKKKKLJLKJJJKILJILIJJJLMLDJLKHKMIKJJIEHIHKJJJEEHH?LKCKJDJLHDLLJBLJGJKKHHIIIIHKKI?JCCGHBGD X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@II +ERR243003.1151913 99 17 3289 60 100M = 3442 253 AGTTCAAGACCAGCCTGGCCAACATGGTGAAACCCCGTCTACTAAAAATACAAAAATTAGCCTGGCGTGGTGGCGCATGCCTGTAATCCCAGCTACTTGG ?EDBEFFIFGGFJIGIIHJGGGGEFIHEJFGHIHHIBEKHDIHDEHIGGFJGFIFFGFFLJIIJHJBFJHFJJJCKGGJLHHKEFFGDIHFJIEAFGBEB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243003 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@GG +ERR243039.1531670 99 17 3295 60 100M = 3652 456 AGACCAGCCTGGCCAACATGGTGAAACCCCGTCTACTAAAAATACAAAAATTAGCCTGGCGTGGTGGCGCATGCCTGTAATCCCAGCTACTTGGGAAGCT ?CDDDEHGFHFDGEHGGGIHHEFHHJHGHCABGIEIHCGHG>F@HHGHHECFDJGIICEFBFJDFK0FBGGDKJEJIEEGIGGIEHHFAID38FDDADE< X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243039 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162875.13732136 83 17 3298 60 100M = 2900 -497 CCAGCCTGGCCAACATGGTGAAACCCCGTCTACTAAAAATACAAAAATTAGCCTGGCGTGGTGGCGCATGCCTGTAATCCCAGCTACTTGGGAAGCTGAG =FHG?JAGGA=G8K?GJ@=EFG@LEDAAGNJHMEEHIHIIIJHH:FF:HA@EKDL<>?FIJJEKEFKB@GJKIIHHGHCGKJJKG?HGFIHHEHGGEFGA X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C +ERR162875.12766080 99 17 3309 60 100M = 3630 420 AACATGGTGAAACCCCGACTACTAAAAATACAAAAATTAGCCTGGCGTGGAGGCGCATGCCTGTAATCCCAGCTACTTGGGAAGCTGAGGGATGAGAACT BB;EEG(>HFFD,F>24*HHG4;GEII3;@IDD3??GDFJ4AF;/K1BK:)B6G2GFE9K2G98IF,J?H=JK=2GI9K.-<98HJK0:9-=4$1;/12%27+28, X0:i:1 X1:i:0 XC:i:93 MD:Z:93 RG:Z:ERR013140 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR242963.128219 99 17 3359 60 100M = 3766 506 TGGCGCATGCCTGTAATCCCAGCTACTTGGGAAGCTGAGGGATGAGAACTGCTTGAACCTGGGAGGCAGACGTTGCAGTGAGCTGAGATCACGCCACTGC ?EAE?GFFHHGHIECDGJFHGGHJDEDEIHFGAKKHJHKBGFGJDEFGGHKJJHKGHIJIJIGGLGJBKGH@DBIJ8I==FIIFJGIE@JFG?G>>@CB> X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR242963 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162872.18600710 83 17 3375 60 100M = 3209 -265 TCCCAGCTACTTGGGAAGCTGAGGGATGAGAACTGCTTGAACCTGGGAGGCAGACGTTGCAGTGAGCTGAGATCACGCCACTGCACTCCAGCCTGGGCAA -EDHDFJ@DKH@JKHIGJJGCMGLEIFL9GJ:KDJJAIMAHJKIJLJELILLLDDJIEIKKHBJKLMILJJHGKGCIIKHLIJJHKHJIIIEIFGEFGBB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A +ERR156632.14578469 99 17 3384 60 100M = 3677 391 CTTGGGAAGCTGAGGGATGAGAACTGCTTGAACCTGGGAGGCAGACGTTGCAGTGAGCTGAGATCACGCCACTGCACTCCAGCCTGGGCAACAGAGTAAT =A7AH;9;.55-+.&132$*8344:$:)$8807;:B<>A=@=A;@@:CDB@EDBCCIGBIFIIHJJJHGFFGJHIDCBD> X0:i:1 X1:i:0 XC:i:66 MD:Z:0T65 RG:Z:ERR013140 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR243043.1629476 83 17 3421 29 100M = 2977 -543 GAGGCGGCCGTTGCAGGGACCTGAGACCCCCCCACTGCCCCCCAGCCTGGGCAACAGAGTAAGCCTCTGTCTCAAAAAAAAAAAAATCACACCATTTTGG B.C;((:#?3H.3*.11-1').:.8,&#'/'9J1;.5B7((F004D9/GHD0>D>=/;-;EG6#F@2E9/>/3CFCFDEFFEFEFGFJCJDHHFFF@E@A MD:Z:5A1A8T2G6T1A1G7A1T22A36 RG:Z:ERR243043 AM:i:29 NM:i:10 SM:i:29 MQ:i:29 XT:A:M BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162875.6771266 147 17 3423 60 100M = 3240 -282 GGCAGACGTTGCAGTGAGCTGAGATCACGCCACTGCACTCCAGCCTGGGCAACAGAGTAAGACTCTGTCTCAAAAAAAAAAAAATCACACCATTTTGGCT @@0AF,6EG4<:.>>F.?H6F8B.4:1@5JHGEHDCBBFKA?KG;A:JEA>HGHIGIHHIHIGIILHLHJKIGGGGHFFE X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@G +ERR243067.219795 99 17 3430 60 100M = 3486 155 GTTGCAGTGAGCTGAGATCACGCCACTGCACTCCAGCCTGGGCAACAGAGTAAGACTCTGTCTCAAAAAAAAAAAAATCACACCATTTTGGCTTCAGATT ?CAFFDHDHFHHIIFJEGIHGAIHHHHIIGGFIIFJIGHIIJJGIHGKHLCBHIFFKJHJFIIJHFHGFGDIGGHF9BH?A7G9AC@HDI-FG9DB9A@> X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243067 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162875.12181062 163 17 3434 60 100M = 3613 278 CAGTGAGCTGAGATCACGCCACTGCACTCCAGCCTGGGCAACAGAGTAAGACTCTGTCTCAAAAAAAAAAAAATCACACCATTTTGGCTTCAGATTGCAT DDHFIHJJJKIKIGKJHBKKJILLGIJLKKINKLKKLKJIJJKMJMGHJKKJMLLLJLLMKJHJJJJEIKIJ;@?EIGH@JJGHCIB?HAFDC1>@H3C3 X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162875.15307937 163 17 3442 29 98M2S = 3853 510 TGAGATCACGCCACTGCACTCCAGCCTGGGCAACAGAGTAAGACTCTGTCTCAAAAAAAAAAAAATAAAACAATTTTGGATTTAGATAGAATATCATCTG BEEEAEIFH@K?BIGED@HJ@/HI9LIKJJCHAEKFGM?EJ:CJCC=EI:FKK<4FB@H=H=45)-*;I2+.;IGBB@A7I2:AFI==73B2G9HGFEHL-IDDHCCDEI>?DFJEDIGAEEEJ/5FGFGFGGFFFFIHIFJEHJGGHHHIJKHGJHFHCGIIFEFFHIFFGC@ X0:i:1 X1:i:0 MD:Z:52^A48 RG:Z:ERR243003 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@efefefca`_]]@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR245041.246570 147 17 3462 60 100M = 3137 -424 CCAGCCTGGGCAACAGAGAAAGACTCTGTCTCAAAAAAAAAAAAATCACACCATTTTGGCTTCAGATTGCATATCCTCCTGCAAGGATATATACGCGTGA ?8/5F*9EA40GD0G8/:$DC:2G-C;7A1.;@E@E=FDD7EFDCHKCHAIFDGHBFFIIG=JHJ?CGJICF5GGHGGKEIGBHBHGCFCDEEAGAGED@ X0:i:1 X1:i:0 MD:Z:18T81 RG:Z:ERR245041 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B +ERR243027.1264030 163 17 3470 29 40M1D13M1I6M1D5M1I23M1D9M2S = 3836 465 GGCAACAGAGTAAGACTCTGTCTCAAAAAAAAAAAAATCAAACATTTTGGCTTCCAGATTCAAATCCCCCCTCAAAGGATAAAAACGCGGAAATTCAAAG A?FGFGGIGLFEGJGHIIHHFIJJIHIFIGGGGFJF&*0>.*J*1G>F1?**6.)1%/G$/<%*/*E*(I4*)0B+=&-/-*7545)*55.GG)C./E*) XC:i:99 MD:Z:40^C1C17^G2T4T3G0C7T1T5^T9 RG:Z:ERR243027 AM:i:29 NM:i:12 SM:i:29 MQ:i:29 XT:A:M BQ:Z:CA@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@IEb@@C@@@@@@A@HL@JfC@@@@@@dICcL@@EU@C@@@@@@@@@@@@@@DC@@@B[@@ +ERR162875.18637663 1187 17 3471 60 100M = 3780 408 GCAACAGAGTAAGACTCTGTCTCAAAAAAAAAAAAATCACACCATTTTGGCTTCAGATTGCATATCCTCCTGCAAGGATATATACGCGTGAAATTCAAGT BDEDGHEHLHIHHJFKJJ:GKLGKDHEJCIJGJJIJ=CHCFHJGGGGCH@EJIFDGK@C;DJJ8:?KIK;;LFE=E4<-I8AA4C=F71AIF8H9=FC8, X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162875.6808869 163 17 3471 60 100M = 3780 408 GCAACAGAGTAAGACTCTGTCTCAAAAAAAAAAAAATCACACCATTTTGGCTTCAGATTGCATATCCTCCTGCAAGGATATATACGCGTGAAATTCAAGT DDDFGGJHKGGHKFIKJLLGKKLIIJIJIIJHHJKICBJJJFJAGIHBLGBFIIIKGJ?CLFFIJJKIKDCGKEHND6DDICEHHAIDBIJIFJEIJDL@FFCFF9HH>EEBB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR243067.219795 147 17 3486 60 100M = 3430 -155 TCTGTCTCAAAAAAAAAAAAATCACACCATTTTGGCTTCAGATTGCATATCCTCCTGCAAGGATATATACGCGTGAAATTCAAGTCAATGACAAATCAGA /B7E4=5:DGFFFFFEFFFEHFKGKFIIGGGHHHJJJIJKLIGHJIHHGFIIFHKGJJFIIKGEGEHFEAJAJGIFFGHFIHLIGIEIGIEIEEEDHFDA X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243067 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C +ERR162875.19273677 147 17 3488 29 6M1I93M = 3143 -443 TGTATCAAAAAAAAAAAAAATCACACCATTTTGGCTTCAGATTGCATATCCTCCTGCAAGGATATATACGCGTGAAATTCAAGTCAATGACAAATCAGAA +CC-*98FHHF;I@(:DC1FIJ:J16A8>)2J3KC3G;ALH<@LF61G6ICB?CI;DACEIBIGG4JDAI:GHGJDB>JFJEBIBC:BGFHHHFD:B X0:i:1 X1:i:0 MD:Z:3C95 RG:Z:ERR162875 AM:i:29 NM:i:2 SM:i:29 MQ:i:29 XT:A:U BQ:Z:@@@@@@@eggeZh\CT^[HY@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A +ERR013140.22233344 163 17 3490 60 108M = 3784 401 TCTCAAAAAAAAAAAAATCACACCATTTTGGCTTCAGATTGCATATCCTCCTGCAAGGATATATACGCGTGAAATTCAAGTCAATGACAAATCAGAAAAAAAAACATA :CEDCDEGGHHHIIIIIGHHEHFJHHEEEELJJEIILHDDEKJIHIJKGJKIEKIHGMGGFEFFFI>LCFHLLHF?DIGEFFJGCFE;HEE@AGCJHIIIIHCF?F>@ X0:i:1 X1:i:0 MD:Z:97G10 RG:Z:ERR013140 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162872.22586072 83 17 3490 60 1S99M = 3226 -362 TTCTCAAAAAAAAAAAAATCACACCATTTTGGCTTCAGATTGCATATCCTCCTGCAAGGATATATACGCGTGAAATTCAAGTCAATGACAAATCAGAAGA .*71578ED=H6?H>D?,DLFJ7B7A=II5C=@JGHEAFIHIGIHBHCDHBL6EAHKB@IGCCEBCDB@CIJDCHEDGHGHEIECFFGI@CGFHGEBGE@ X0:i:1 X1:i:0 XC:i:99 MD:Z:99 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B +ERR243091.881299 83 17 3491 60 100M = 3174 -416 CTCAAAAAAAAAAAAATCACACCATTTTGGCTTCAGATTGCATATCCTCCTGCAAGGATATATACGCGTGAAATTCAAGTCAATGACAAATCAGAAAAAA C5;=CAAEFDFEEEEBCI;JFIKHGHGHIIKGEKGJIGGIJG=GDIKGFIHIJEIHJFFFFDDDAI>IDJDFGFEIFGHGIFGFJFIDFGEHGGDB@A@? X0:i:1 X1:i:0 MD:Z:96G3 RG:Z:ERR243091 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@PSRW_`_^ +ERR162875.1328730 147 17 3494 60 100M = 3121 -472 AAAAAAAAAAAAATCACACCATTTTGGCTTCAGATTGCATATCCTCCTGCAAGGATATATACGCGTGAAATTCAAGTCAATGACAAATCAGAAGAAAAAA 0ACDFDC9GCF?CGKF:GHLIHJKJIJNJIKIEI2B6FJJJIALHIJKLKHLJKIEJHIH>DGBKJLIIJIIKDIGGLIIALIKHGGHKIJGJHFFDC?E X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@GHIJHF@IDF@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ADCDAH +ERR242955.586810 99 17 3506 60 100M = 3917 510 ATCACACCATTTTGGCTTCAGATTGCATATCCTCCTGCAAGGATATATACGCGTGAAATTCAAGTCAATGACAAATCAGAAAAAAAAACATATATATACG ?@CCEAEDBDDDEG6GG-IFFCC8FFGEADFHFIHFCAJFDFI9EI6HE>F;BBFGBF4FEAEC>ACEA7?A7 X0:i:1 X1:i:0 MD:Z:81G18 RG:Z:ERR242955 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR243031.650799 147 17 3507 60 100M = 3080 -526 TCACACCATTTTGGCTTCAGATTGCATATCCTCCTGCAAGGATATATACGCGTGAAATTCAAGTCAATGACAAATCAGAAAAAAAAACATATATATACGC >GCH1GFFHGHHHFGFGIHHHEEIIIFI;GIAADHIDFFI@HDHAGD>BIAHHIEFBID>FIEFHHFGHDIFFHDEGGEFDEEEFFEJHEGEF@FDD?CA X0:i:1 X1:i:0 MD:Z:80G19 RG:Z:ERR243031 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162872.8738223 99 17 3511 60 100M = 3914 502 ACCATTTTGGCTTCAGATTGCATATCCTCCTGCAAGGATATATACGCGTGAAATTCAAGTCAATGACAAATCAGAAAAAAAAACATAAATATACGCAAAC BDDCFBAAIEBIDBGKHE=8DDGGHGHJJDFHHD;LC<=>C=GHKI:?IJB@@H7AHHB0:)J@H(AF:C@HA/378@ X0:i:1 X1:i:0 MD:Z:76G10T12 RG:Z:ERR162872 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B +ERR243031.386955 83 17 3511 60 100M = 3144 -466 CCCATTTTGGCTTCAGATTGCATATCCTCCTGCAAGGATATATACGCGTGAAATTCAAGTCAATGACAAATCAGAAGAAAAAACATATATATACGCAAAC $FC@@D>FJJJAFIJIHEJKJHA@GHKHKKHKJCIGJDFHCHFEBJAJHLGEFHGHEIICJEGGJGHFFGGJIIFCIEFCDDEJFDGEGDFDEAFHBAB? X0:i:1 X1:i:0 MD:Z:0A99 RG:Z:ERR243031 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@IB@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A +ERR243059.116527 99 17 3516 60 100M = 3914 497 TTTGGCTTCAGATTGCATATCCTCCTGCAAGGATATATACGCGTGAAATTCAAGTCAATGACAAATCAGAAAAAAAAACATATATATACGCAAACCAGTA @@AFCGGDGFJFGEJIFFFFIGHIHHIHGIKIGEDGCGEHAI@EIEEFHCJG@JEJFHHJFHFHGJJEJGIHEGGHHAJGGEGEGDHEH?JDFHE@CDB@ X0:i:1 X1:i:0 MD:Z:71G28 RG:Z:ERR243059 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:EEC@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162872.4686821 163 17 3525 60 100M = 3871 445 AGATTGCATATCCTCCTGCAAGGATATATACGCGTGAAATTCAAGTCAATGACAAATCAGAAGAAAAAACATATATATACGCAAACCAGTATCCTACTGT EEEFEJJGHHIJKKLKLLJIHLMJJJJJKJJFLEILHJJIIKKIMHNJJJMKKKJIJJKLJKMKKIKKJKKGHGIIJJIKCKJJIJKJMFCHEIGEEGG< X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A@ +ERR242971.1136963 99 17 3535 60 100M = 3893 457 TCCTCCTGCAAGGATATATACGCGTGAAATTCAAGTCAATGACAAATCAGAAAAAAAAACATATATATACGCAAACCAGTATCCTACTGTGTGTGTCGTT ?DDEFFDHGFCI5GFCFDCBGAI@?IF9A>AJHGKD@@ X0:i:1 X1:i:0 MD:Z:52G47 RG:Z:ERR242971 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@BE +ERR243027.47729 147 17 3547 60 100M = 3134 -512 GATATATACGCGTGAAATTCAAGTCAATGACAAATCAGAAGAAAAAACATATATATACGCAAACCAGTATCCTACTGTGTGTGTCGTTTGTTGTGTTTTC DB?FDE?CAH@FFJGFAGGIEIIGKFIIICKFEGIDJIFJJFFIHE>IHDHFHEDEDCIJFEEJIIIEFHGLDFKCHHGHHIHEBHCHHHFHGGGDFDCA X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243027 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR016352.1106475 163 17 3557 60 108M = 3858 408 CGTGAAATTCAAGTCAATGACAAATCAGAAGAAAAAACATATATATACGCAAACCAGTATCCTACTGTGTGTGTCGTTTGTTGTGTTTTCGACAGCTGTCCGTGTTAT ;:CCDDCDCEGHGGFHIEGIDHIIGGFH>IIAFJ?JDEIHHHHH?HHF8HJEK3HBGFADFIKEI;F;HGFEKDGHGHAFGH?FHEH=AGHFIFGHG@JFIGGJGFGE@FEEBAB? X0:i:1 X1:i:0 MD:Z:22G77 RG:Z:ERR242963 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR242963.383553 83 17 3565 60 100M = 3234 -430 TCAAGTCAATGACAAATCAGAAAAAAAAACATATATATACGCAAACCAGTATCCTACTGTGTGTGTCGTTTGTTGTGTTTTCGACAGCTGTCCGTGTTAT B>DAB9>7>CD=C@B;@EC X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243087 AM:i:18 NM:i:0 SM:i:37 MQ:i:55 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR156632.10508568 83 17 3608 60 100M = 3407 -300 AACCAGTATCCTACTGTGTGTGTCGTTTGTTGTGTTTTCGACAGCTGTCCGTGTTATAATAATTCCTCTAGTTCAAATTTATTCATTTTTAACTTCATAG >EBGIFGFIJMJBLIIKIJJJJHDJIKKKJJJJJFJJIELIMLLLJJFJDKKKKIJJIIIIHIHJMIMILJIIKHHIGJIHIJLIFJIIHFGJHIIFAED X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR156632 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@G@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162875.12181062 83 17 3613 60 100M = 3434 -278 GTATCCTACTGTGTGTGTCGTTTGTTGTGTTTTCGACAGCTGTCCGTGTTATAATAATTCCTCTAGTTCAAATTTATTCATTTTTAACTTCATAGTACCA BCFB?IFBLHIHGB7JI=.>EJI8&FKF+IGB7H2JIF7F=?CF5A2+? X0:i:1 X1:i:0 MD:Z:84C15 RG:Z:ERR162872 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A +ERR242975.161746 163 17 3623 60 100M = 4004 480 GTGTGTGTCGTTTGTTGTGTTTTCGACAGCTGTCCGTGTTATAATAATTCCTCTAGTTCAAATTTATTCATTTTTAACTTCATAGTACCACATTCTACAC @CGEHDIEIAFEFIEEIFIDFFFI?FIEIJHIEIGBEJEFDCFHGFIDHKHJJJELEBHGHBHGFGHFLGHEFECFHJHEJHFFKGAHDEAHGCIFBFD> X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR242975 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162875.18994301 83 17 3627 60 100M = 3289 -437 GTGTCGTTTGTTGTGTTTTCGACAGCTGTCCGTGTTATAATAATTCCTCTAGTTCAAATTTATTCATTTTTAACTTCATAGTACCACATTCTACACACTG ?DEE=HCEFHIHJIJBHJIDGHLLKIFIJCDKJKEIJIIIIHJJFJMELHHKKJLHIHIKIIIILHIJIHIHHLIHIIIKHGGHKHJGGGJFFIFHFGEB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162875.12766080 147 17 3630 60 100M = 3309 -420 TCGTTTGTTGTGTTTTCGACAGCTGTCCGTGTTATAATAATTCCTCTAGTTCAAATTTATTCATTTTTAACTTCATAGTACCACATTCTACACACTGCCC :==>CF@1DIH4=GCE2L9:8A9EB4/:8JKJHC5CIH3CKE;7EGGE?EDI?=IGEG?IGGG@HFGIHGGFFGHFEIGF6FG6H:CFGAIHJIFAA<=?HBGKGFF8FDHF@?GGIJG9CGHAGH>I.HH?;><;BAFHIHEKHHHAIILFDIHIDGKIGGKFJJLHJJBJFJAHGJKHLJHJADKKIDGDEKL;=DEF;EFFEH>CEGAAKEJFHHHEKEDG?IFGAGJCIHHIGGFHDFIFEHJB>HKDIHHAK=?JEKGKHJHGIGIEH?EHHHIEGGIFF@D=GC@ X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243039 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B +ERR156632.301185 163 17 3655 60 100M = 3885 329 TCCGTGTTATAATAATTCCTCTAGTTCAAATTTATTCATTTTTAACTTCATAGTACCACATTCTACACACTGCCCATGTCCCCTCAAGCTTCCCCTGGCT BDC@EHFDFFFHGGDGGJJJKKIKFGFIIFHGEHHHJFHHIJGIIILGJIHHMHIJLIKEJIKLKEFJJJLLHLKJIHGLLLKLKDIMFKGIJJHHDD@: X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR156632 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162872.9849990 163 17 3663 60 100M = 3854 290 ATAATAATTCCTCTAGTTCAAATTTATTCATTTTTAACTTCATAGTACCACATTCTACACACTGCCCATGTCCCCTCAAGCTTCCCCTGGCTCCTGCAAC EADFFGHGGKJKKLJKIHJJKIJHIJJHMHJJIIHGHKMHMJJIMHKJLIKJJIMMCILIKKLLKLIEHLJMKLKNMK@MJKHLLKLKKIKKJIIHFCDE X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@G +ERR156632.14578469 147 17 3677 60 1S99M = 3384 -391 TAGTTCAAATTTATTCATTTTTAACTTCATAGTACCACATTCTACACACTGCCCATGTCCCCTCAAGCTTCCCCTGTCTCCTGCAACCACAAATCTACTC /.D1G.8'@12H+3IKHF>JJ@';7II::8LK80HME:-)8;I=:,:1BIL0.J;I6EM2'//H4<8>I/70G1.I-005L=JI5@F>>2EE2?@E5A:? X0:i:1 X1:i:0 XC:i:99 MD:Z:75G23 RG:Z:ERR156632 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR243079.290863 163 17 3688 37 100M = 4062 473 ATTCATTTTTAACTTCATAGTACCACATTCTACACACTGCCCATGTCCCCTCAAGCTTCCCCTGGCTCCTGCAACCACAAATCTACTCTCTGCCTCTGTG ?BAFCDDCDCEFGGEIEGEIDDGHFGHGFGICHGDEILIGJIHIJCHIHHJMGEKIJEGHGGJHHIIKJJBIHEIHIIJEHGJIAHJLIJHDJFCFGDAE X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243079 AM:i:0 NM:i:0 SM:i:37 MQ:i:7 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@G +ERR016352.12571677 163 17 3692 60 108M = 4043 458 ATTTTTAACTTCATAGTACCACATTCTACACACTGCCCATGTCCCCTCAAGCTTCCCCTGGCTCCTGCAACCACAAATCTACTCTCTGCCTCTGTGGGTTGACCTATT :BAA@@BFBGDFGFFHGFDGHDHGEGIG?IEEEIHHHHIHIIHHFHJHIFJDJFGFHIJFIIJEIID8AFEGIEIIIGEIGFJAJ@F=?IK=JH?FBFDFF@;;<@ED X0:i:1 X1:i:0 MD:Z:108 RG:Z:ERR016352 AM:i:23 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C +ERR242955.298650 99 17 3708 37 100M = 4076 467 TACCACATTCTACACACTGCCCATGTCCCCTCAAGCTTCCCCTGGCTCCTGCAACCACAAATCTACTCTCTGCCTCTGTGGGTTGACCTATTCTGGACAC ?ADCFFFDBGHDHGIGHGFJHGFFI?IHHIHGBFJKIGJDGIEKHKGJJJHJFIGHGIHIGFIIGIHJJJEJLHIEFIDJGHGAHFHGGBFCCFH?CAEA X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR242955 AM:i:0 NM:i:0 SM:i:37 MQ:i:0 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162872.16735015 99 17 3713 60 100M = 3988 374 CATTCTACACACTGCCCATGTCCCCTCAAGCTTCCCCTGGCTCCTGCAACCACAAATCTACTCTCTGCCTCTGTGGGTTGACCTATTCTGGACACGTCAT B;ICDHEF4BBFH0GJC.:F;MKK.AH6FEL=5IGIFA9GFILF5J8<@G7AH/LI&+>.CDIJF,7K669G;, X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR243031.299961 163 17 3714 37 100M = 4080 465 ATTCTACACACTGCCCATGTCCCCTCAAGCTTCCCCTGGCTCCTGCAACCACAAATCTACTCTCTGCCTCTGTGGGTTGACCTATTCTGGACACGTCATA ?B@EGCBHEHFEFEHHDGIEIGHHCK@HDBG@IFFD=?BC=E@CEHEH;HHICGHHGIEF>FJIIJAIBIIEGG=DE@<@I;H=HBFIC0F7FF@1DAA: X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243031 AM:i:0 NM:i:0 SM:i:37 MQ:i:7 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR243047.429920 163 17 3715 37 100M = 4067 451 TTCTACACACTGCCCATGTCCCCTCAAGCTTCCCCTGGCTCCTGCAACCACAAATCTACTCTCTGCCTCTGTGGGTTAACCTATTCTGGACACGTCATAG @ADEBEFGCGGIJFHFGIGIGHGHHFFJI=?JGFHGGGGGJGGJFHHHDIGDHGDJIDIJJIJKKJ;JHFJ;DGDCEGNHDBDHEJIICGHFF7DAE@5> X0:i:1 X1:i:0 MD:Z:77G22 RG:Z:ERR243047 AM:i:0 NM:i:1 SM:i:37 MQ:i:7 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR013140.12000443 163 17 3721 57 108M = 4045 401 ACACTGCCCATGTCCCCTCAAGCTTCCCCTGGCTCCTGCAACCACAAATCTACTCTCTGCCTCTGTGGGTTGACCTATTCTGGACACGTCCTAGAAATAGAGTCCTGC :ADBDCAFGFFGA?IGGAABEBIF=?DBA?AD@B@B?@AB?49B?B??<>?@;B687?96BDB?177)43:@?28B>6963%842;(->,1<3:33?21/24%3,A@0 X0:i:1 X1:i:0 MD:Z:90A17 RG:Z:ERR013140 AM:i:20 NM:i:1 SM:i:37 MQ:i:57 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR013140.3552250 163 17 3731 10 108M = 4051 394 TGTCCCCTCAAGCTTCCCCTCGCTCCTGCAACCACAAATCTACTCTCCGCCTCTCTGGGCTGACCTATTCTCGACACGTTCTAGAAATAGAGTCCTGCCAAACGTCGC /<@70(/>3061&A57-(#.%23.,4>@01B95B>>3:#/&AF@D+B/;%&FCB1+F3@<6B)-,:7%)9'8B<+0D7359F@7@49?@$>/B3(//). MD:Z:20G26T6G4T11G7C0A17A1C4G2 RG:Z:ERR013140 AM:i:10 NM:i:10 SM:i:10 MQ:i:10 XT:A:M BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162875.7468652 99 17 3733 60 100M = 3865 231 TCCCCTCAAGCTTCCCCTGGCTCCTGCAACCACAAATCTACTCTCTGCCTCTGTGGGTTGACCTATTCTGGACACGTCATAGAAATAGAGTCCTGCAACA AECDFHGFFJHIGJJIIJJ0KJKJGKJIIIJHHIGHJKKIKLLLLLLIKKLKKEKEBIHKJFLHIKIKMMHJIJJDHLHIFMIIFJDJIMGIJIIGFDD@ X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR245049.438880 99 17 3734 60 100M = 4134 499 CCCCTCAAGCTTCCCCTGGCTCCTGCAACCACAAATCTACTCTCTGCCTCTGTGGGTTGACCTATTCTGGACACGTCATAGAAATAGAGTCCTGCAACAC ?BAEFGFFIHHEJGHFHIDIHHGDGIHGHGEIGHGIKIEJHKHJGIIHDKIJFEA@EEJGHIGEFFKMJG9JFJAGKGCDHDHIGFI?KDFHH?IF?ECD X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR245049 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162872.10931516 163 17 3750 37 100M = 4074 423 TGGCTCCTGCAACCACAAATCTACTCTCTGCCTCTGTGGGTTGACCTATTCTGGACACGTCATAGAAATAGAGTCCTGCAACACGTGGCCGTCTGTGTCT @FBCBIJJKJFHFCFJFEDHLIHDMILFJLBLLILI?MHE;J8BFL=CJGFMJMDDK/LKGHJBGDILF) X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:0 NM:i:0 SM:i:37 MQ:i:0 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR243075.758288 163 17 3764 60 100M = 4186 521 ACAAATCTACTCTCTGCCTCTGTGGGTTGACCTATTCTGGACACGTCATAGAAATAGAGTCCTGCAACACGTGGCCGTCTGTGTCTGGCTTCTCTCGCTT ACECFEHGFHHIIIIJHHIIIJFJJHEEJFHHIFGGKJLHHBGJBGIFGELGHHHEJGLELIJIKIHMGIAELIIIDGJKJFJFKIIIHHDGHIGH=EF@ X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243075 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A@ +ERR242963.128219 147 17 3766 60 100M = 3359 -506 AAATCTACTCTCTGCCTCTGTGGGTTGACCTATTCTGGACACGTCATAGAAATAGAGTCCTGCAACACGTGGCCGTCTGTGTCTGGCTTCTCTCGCTTAG =>AAICDJEJEJHJIKDKHGHHGJBGGCFJHAIHLGGKFJDBHHJDFKJFCGFIILG@JKHIHFDJEAIDJFG@HGGGFGIGKGGHJFFJFIF?JJBBD@ X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR242963 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR013140.23480670 73 17 3771 37 108M = 3771 0 TACTCTCTGCCTCTGTGGGTTGACCTATTCTGGACACGTCATAGAAATAGAGTCCTGCAACACGTGGCCGTCTGTGTCTGGCTTCTCTCGCTTAGCATCTTGTTTCCC @?@@DIEHB>GHIJHEBKKFDGGFDKGEEIGCHJGFF=FEKHHGHDFG>FDD?F@DEDGEDKHAIFGCH@EEHGGC>@EC@-G=6D+8(9?F?4B=>E>GAFA@);9# X0:i:1 X1:i:0 MD:Z:107A0 RG:Z:ERR013140 AM:i:0 NM:i:1 SM:i:37 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR013140.23480670 133 17 3771 0 35M73S = 3771 0 TTCTCATCAATCCCTCATCTCTTATAACCATTTCGGTCCTTTCGGCCCTACAGCCACCTTGTTTATACTTGGTAAGACCCACACCACTCGCCAACTTACTCTACTCCC 8+7?5>09:),/%81,$,7<+?)+1+*+),3%5+)#%(4B%$&'%'/*@,)*%%&,%(/0%-&$$*$-,$3*.%/$:%$+.$*%&+.,.%%,%(%7(-.-',1*6%&$ XC:i:35 RG:Z:ERR013140 +ERR162875.18637663 1107 17 3780 60 100M = 3471 -408 CCTCTGTGGGTTGACCTATTCTGGACACGTCATAGAAATAGAGTCCTGCAACACGTGGCCGTCTGTGTCTGGCTTCTCTCGCTTAGCATCTTGTTTCCAA 0GBCBHDJFC6IKG.?HA?>F:JM8LECJIAEHMHHFIBLK8K=E:6DAIGH:JBFIJJG>MIKKMIIIJKG=E??DC8DCABCGGFDH:BA::<>>8<67=8?>0A X0:i:1 X1:i:0 MD:Z:108 RG:Z:ERR013140 AM:i:0 NM:i:0 SM:i:37 MQ:i:7 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A +ERR013140.22233344 83 17 3784 60 108M = 3490 -401 TGTGGGTTGACCTATTCTGGACACGTCATAGAAATAGAGTCCTGCAACACGTGGCCGTCTGTGTCTGGCTTCTCTCGCTTAGCATCTTGTTTCCAAGGTCCTCCCACA 3:;8-9?=@=;AACF==EEG@H@@?A>DCF=?@ED=@9@CB:=BBJG?FHFLHLHIIHLJIKKIHIH@JIJHKIIGKHJKFJJGIHGJJEIHGIGGDCA@ X0:i:1 X1:i:0 MD:Z:108 RG:Z:ERR013140 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162872.15409720 83 17 3810 60 100M = 3484 -425 CATAGAAATAGAGTCCTGCAACACGTGGCCGTCTGTGTCTGGCTTCTCTCGCTTAGCATCTTGTTTCCAAGGTCCTCCCACAGTGTAGCATGCACCTGCT CADGGEEIHKKDIIIIIJKBIJIDIGGHJ=JKNJIJJILJIKMIIEFLJEMLJGILIIJLHJJHEBIKGJGJJJIIIIKHKKIHIGJJIGGHIFFHEEGB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR242975.1167526 163 17 3819 29 100M = 4160 433 AGAGTCCTGCAACACGTGGCCGTCTGTGTCTGGCTTCTCTCGCTTAGCATCTTGTTTCCAAGGTCCTCCCACAGTGTAGCATGCACCTGCTACACTCCTT @EDHEHGIIHHGIEI@GJHHHAFGJKFIFJHIIIIDKJFIG@JIGALJCIJJFKEDEJEHHJJGJIFJHGIHGKFJEFJKEJHJGHGIIIHHDEGFGDEB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR242975 AM:i:29 NM:i:0 SM:i:29 MQ:i:29 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A +ERR013140.9944053 163 17 3821 60 92M16S = 4143 402 AGTCCTGCAACACGTGGCCGTCTGTGTCTGGCTTCTCTCGCTTAGCATCTTGTTTCCAAGGTCCTCCCACAGTGTAGCATGCACCTGCTACACTCTTTCTTACGGCTG 9AABCCCDEA=EB:CBBD?>EIIEACC;DDE@F@9F0@>45C7:<2=>6CFACE@6@7=50>93&=-48693<@89AA3<*,=A58<44352/%)'/'$%,$$70 X0:i:1 X1:i:0 XC:i:92 MD:Z:92 RG:Z:ERR013140 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162875.26059461 163 17 3830 57 100M = 4037 306 ACACGTGGCCGTCTGTGTCTGGCTTCTCTCGCTTAGCATCTTGTTTCCAAGGTCCTCCCACAGTGTAGCATGCACCTGCTACACTCCTTCTTAGGGCTGA DACBBH7-AG=HJK=FKDIIB9:M1;GJ=DC@IFBBKGHDLH;GHGK:I>J129CJEFJ8G>M=D99A X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:20 NM:i:0 SM:i:37 MQ:i:57 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR243047.360466 99 17 3832 60 100M = 4185 452 ACGTGGCCGTCTGTGTCTGGCTTCTCTCGCTTAGCATCTTGTTTCCAAGGTCCTCCCACAGTGTAGCATGCACCTGCTACACTCCTTCTTAGGGCTGATA @-=CGEEAGEFF;5>CL31D5CC@JHCD/>G26@JGHECFIE7G>BC>GG;III2D@24/'.G>6,90 X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR243047 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR243027.1264030 83 17 3836 29 100M = 3470 -465 GGCCGTCTGTGTCTGGCTTCTCTCGCTTAGCATCTTGTTTCCAAGGTCCTCCCACAGTGTAGCATGCACCTGCTACACTCCTTCTTAGGGCTGATATTCC 9>B=A@=>ABAA@@>9;7>5<=?:29 X0:i:1 X1:i:0 MD:Z:83A24 RG:Z:ERR013140 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162875.15307937 83 17 3853 29 100M = 3442 -510 TTCTCTCGCTTAGCATCTTGTTTCCAAGGTCCTCCCACAGTGTAGCATGCACCTGCTACACTCCTTCTTAGGGCTGATATTCCGCGCACCTGCTACACTC =>B)IDA7FC8D/DHIF1GJ11J?G=L6DEA>HEE:AGKJ>?AJIJJ4CD;=8HKFIAFDCGBI23EHCLKB5C@JIHG6IDC+BGF>HJ;+IEGGFGDB X0:i:1 X1:i:0 MD:Z:83A16 RG:Z:ERR162875 AM:i:29 NM:i:1 SM:i:29 MQ:i:29 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D +ERR162872.9849990 83 17 3854 60 100M = 3663 -290 TCTCTCGCTTAGCATCTTGTTTCCAAGGTCCTCCCACAGTGTAGCATGCACCTGCTACACTCCTTCTTAGGGCTGATATTCCGCGCACCTGCTACACTCC CHFHG=HKHHJJKBGKIBJICHJLGLLEIMMHKJMIKLKKHIIKKJJJMJJLILMGGKFLIKMJJMGGLKKKMIKJHIGIJCICJJGJJGIIEFHFHE>B X0:i:1 X1:i:0 MD:Z:82A17 RG:Z:ERR162872 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162872.20934779 83 17 3855 60 100M = 3616 -338 CTCTCGCTTAGCATCTTGTTTCCAAGGTCCTCCCACAGTTTAGCATACACCTGCTACACTCCTTCTTAGGGCTGATATTCCACGCACCTGCTACACTCCT C:>>A6-'07KJDD7D92002-I&K(G2&92/;B98MFH)HB2BCA-E/4KI>.DIG8AIB=HE:C7J+@3KHJB6CDDHDEFGGAABEHDHHIKBFJGKHIJIIJJGKGGK?JFK=B@HDKJHBGJHGKKJKHKHHKIIIJJEGHIKKIJIAIIJKJJIJHIIIJGIIJJIIGGHEDDCA X0:i:1 X1:i:0 MD:Z:108 RG:Z:ERR016352 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR016352.8064738 163 17 3861 37 108M = 4107 353 CTTAGCATCTTGTTTCCAAGGTCCTCCCACAGTGTAGCATGCACCTGCTACACTCCTTCTTAGGGCTGATATTCCACGCACCTGCTACACTCCTTCTTATGGCTGATA :B@AA@CCBEDDEDDCDFFEGDCDGDDDFCG@EFGEGEGGGFA?@IGFHE@DDHEFIGFIHGHFI7E?GAGHIGBIE9FHEHKDEJF6FBJ=BFC?HIEAH9AGFB5? X0:i:1 X1:i:0 MD:Z:108 RG:Z:ERR016352 AM:i:0 NM:i:0 SM:i:37 MQ:i:8 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162875.7468652 147 17 3865 60 100M = 3733 -231 GCATCTTGTTTCCAAGGTCCTCCCACAGTGTAGCATGCACCTGCTACACTCCTTCTTAGGGCTGATATTCCGCGCACCTGCTACACTCCTTCTTATGGCT DF@FJFHGGIDILFLJKHJMIIKKEJKIJHHLKLJKLLIKMEKMIIMJLEGLIIMGIMKLLMGHJIJJHKDJDKLEJMGLMIILIMFKKDHKGGHGEFFD X0:i:1 X1:i:0 MD:Z:71A28 RG:Z:ERR162875 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR016352.9446395 83 17 3871 60 108M = 3647 -331 TGTTTCCAAGGTCCTCCCACAGTGTAGCATGCACCTGCTACACTCCTTCTTAGGGCTGATATTCCGCGCACCTGCTACACTCCTTCTTATGGCTGATATTCCACGCAC A8ABBFFFFB=GIHEHIHHJKBH?EKBJCGHJFEFGDHGHJHKGEJHLKKEKFJJKBIIII=KKAIAIJHKJG@JEFJIJEJJHGJFCIBHHJGGHGHDCIHGGHA>D@>AE9>E?: X0:i:1 X1:i:0 MD:Z:61A46 RG:Z:ERR016352 AM:i:20 NM:i:1 SM:i:37 MQ:i:57 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162875.919124 99 17 3879 37 100M = 4109 329 AGGTCCTCCCACAGTGTAGCATGCACCTGCTACACTCCTTCTTAGGGCTGATATTCCACGCACCTGCTACACTCCTTCTTATGGCTGATATTCCACGCAC BG@FFFIHGHGGHJHKGHKJIHLLIJJKLKLHKIILIKKHMLHDJKMLKDGIHJILLJBDKJIKIILFAKJDAEH@BKKFF6KIEJK&G8HEB>DB;EDA X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162875 AM:i:0 NM:i:0 SM:i:37 MQ:i:0 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C +ERR013140.17460076 163 17 3883 60 108M = 4144 368 CCTCCCACAGTGTAGCATGCACCTGCTACACTCCTTCTTAGGGCTGATATTCCGCGCACCTGCTACACTCCTTCTTATGGCTGATATTCCACGCACCTGCTACACTCC :DEDDDDCFEBGCFCFE?CBHFJGBDEGGEGFDJJEJHEACGGDEFDA?EBBC1B:@ECDFB@EA>?=E?CAA@F;98@9AECDCA@>=;C@7;=7-2?>A=99.@84 X0:i:1 X1:i:0 MD:Z:53A54 RG:Z:ERR013140 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR156632.301185 83 17 3885 60 100M = 3655 -329 TCCCACAGTGTAGCATGCACCTGCTACACTCCTTCTTAGGGCTGATATTCCACGCACCTGCTACACTCCTTCTTATGGCTGATATTCCACGCACCTGCTA :CBGFIIGHIIJKJHKLKFLKJLLHFECKIILKJMFJMLMLMJLKLIIIILHEKKILNJLLEHJGMJLMJJLIJIJKLMKKIHIIIKKGCJJFIKGHGCD X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR156632 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR242971.1136963 147 17 3893 60 100M = 3535 -457 TGTAGCATGCACCTGCTACACTCCTTCTTAGGGCTGATATTCCGCGCACCTGCTACACTCCTTCTTATGGCTGATATTCCACGCACCTGCTACACTCCTT 0EA=GFDB3FBDEIGJHGGDGHIEBJJDFK72+?./;6-6->D8ABFCCFHAEJEBAGHBEEFCDE=>:@DBHGHAHDEEBCDFDDHJDFHILJLGCHEGDCEFD@JICJHJIHHFHEHJDHDEGCBC6EFDEC@ X0:i:1 X1:i:0 MD:Z:40A60G1G4 RG:Z:ERR013140 AM:i:37 NM:i:3 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR243087.1477801 83 17 3909 55 100M = 3600 -408 TACACTCCTTCTTAGGGCTGATATTCCACGCACCTGCTACACTCCTTCTTATGGCTGATATTCCACGCACCTGCTACACTCCTTCTTAGGGCTGATATTC 0?F?HBFJGGK:DHHII@FGHDFEEHJFBHJHGKICJ@BKEFGFH@EJGCB:HHJHGGEGFDEJD@HFDGKGIH@FJ?LFA>EHJGDIEEHKEGDBCCB? X0:i:1 X1:i:3 XA:Z:17,-4057,100M,1;17,-4094,100M,1;17,-4168,100M,1; MD:Z:100 RG:Z:ERR243087 AM:i:18 NM:i:0 SM:i:18 MQ:i:55 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A +ERR013140.18542909 163 17 3912 60 108M = 4185 380 ACTCCTTCTTAGGGCTGATATTCCACGCACCTGCTACACTCCTTCTTATGGCTGATATTCCACGCACCTGCTACACTCCTTCTTAGGGCTGATATTCCACACACCCGC :AEDDD@EGBFIJJIIHIGGGDIJHG;<9+&$&$&-. X0:i:1 X1:i:0 MD:Z:108 RG:Z:ERR013140 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162872.8738223 147 17 3914 60 100M = 3511 -502 TCCTTCTTAGGGCTGATATTCCGCGCACCTGCTACACTCCTTCTTATGGCTGATATTCCACGCACCTGCTACACTCCTTCTTAGGGCTGATATTCCACAC -E8?FIGCF:AKEDCFFH>JADKDDL:9JIHKIIJII>DC@GA3F;GDJHFLIJFEIDLHDLLEKIFMMGGJ>JHLJIIMIEJKKLLGJIHHFHHIEGDB X0:i:1 X1:i:0 MD:Z:22A77 RG:Z:ERR162872 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@CAB +ERR243059.116527 147 17 3914 60 100M = 3516 -497 TCCTTCTTAGGGCTGATATTCCGCGCACCTGCTACACTCCTTCTTATGGCTGATATTCCACGCACCTGCTACACTCCTTCTTAGGGCTGATATTCCACAC =EGADGGDIHHGIGKGGIJGICJCJKGHKIIJFDJFLIHJIGJEFHIHIJLIGFIIFHIDBJJ?EKHKKDFKDKGGKGGIHFJHHIJGJGCFHFCHEGC@ X0:i:1 X1:i:0 MD:Z:22A77 RG:Z:ERR243059 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C@@ +ERR242955.586810 147 17 3917 60 100M = 3506 -510 TTCTTAGGGCTGATATTCCGCGCACCTGCTACACTCCTTCTTATGGCTGATATTCCACGCACCTGCTACACTCCTTCTTAGGGCTGATATTCCACACACC (C7BB7FG28FJ9E>BAJ3CGHHJEEEDJ>GKGHIHFIEGJCHJHAGGF;IDIBGE>A X0:i:1 X1:i:0 MD:Z:19A80 RG:Z:ERR242955 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@F +ERR245032.607478 99 17 3950 60 100M = 4200 348 CTCCTTCTTATGGCTGATATTCCACGCACCTGCTACACTCCTTCTTAGGGCTGATATTCCACACACCCGCTACACTCCTTCTTAGGGCTGATATTCCACG ADCDG?GHCDGFJFEG>D@E?@HGDFGHH=EEIHFGFC?GGIIHCIEFED>H>0@CI4(.=FA;,J/.4./BF7?3.@9B7 X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR245032 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR016352.14078817 163 17 3952 60 106M2S = 4187 342 CCTTCTTATGGCTGATATTCCACGCACCTGCTACACTCCTTCTTAGGGCTGATATTCCACACACCCGCTACACTCCTTCTTAGGGCTGATATTCCACGCCCCCGCTAA :?CA@CABDDEDEE>CCEF@DFB'42C;6HBI@9CF8K@6F;E7C>?;D=D6JG?;)>FD:,9HI<.:BIDB0GJHA.3.2IH>HC?0E:@9G+BG82*@B;,BFFFFBB X0:i:1 X1:i:0 MD:Z:69G30 RG:Z:ERR242975 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D +ERR013140.11440888 163 17 3974 60 108M = 4283 416 CGCACCTGCTACACTCCTTCTTAGGGCTGATATTCCACACACCCGCTACACTCCTTCTTAGGGCTGATATTCCACGCACCCGCTACACTCCTTCTTAGGGCTGATATT :?F>=:+6/@7>>:@2 X0:i:1 X1:i:0 MD:Z:108 RG:Z:ERR013140 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR156632.11081426 147 17 3977 60 100M = 3652 -424 CCCTGCTACACTCCTTCTTAGGGCTGATATTCCACACACCCGCTACACTCCTTCTTAGGGCTGATATTCCACGCACCCGCTACACTCCTTCTTAGGGCTG #6DGGIHEBALI4LIDKFAIKL1AIDCA@JJ?LIK=I0LG=DBI=LEKI7LHICI:KKJ7;HEHHHCIJKACBIGJIB:JE>J?HHFECGHFFFEFDGFB X0:i:1 X1:i:0 MD:Z:0A99 RG:Z:ERR156632 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR162872.22176921 99 17 3984 37 100M = 4109 224 ACACTCCTTCTTAGGGCTGATATTCCACACACCCGCTACACTCCTTCTTAGGGCTGATATTCCACGCACCCGCTACACTCCTTCTTAGGGCTGATATTCC BDEEHGGIEIIEGJIHJKKIIHIHKKIJDJIJKKCKLGKIIMKKHHKLHIDMGLJKIJDJEHKKJEKHHK:DKDH8IFJJKBGEIF>IHGBHGFGFE=FC X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR162872 AM:i:0 NM:i:0 SM:i:37 MQ:i:7 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@AB +ERR162872.16735015 147 17 3988 60 100M = 3713 -374 TCCTTCTTAGGGCTGATTTGCCACACACCCGCTCCACTCCTTCTTAGGGCTGATATTCCACGCACCCGCTACACTCCTTCTTAGGGCTGATATTCCACGC -6<2;D9H?:AJLDH7?)K0/LH:FF,&3??M4'N2/&0N@J:7;LFJCG7)@HIF=C@ X0:i:1 X1:i:0 MD:Z:17A1T13A66 RG:Z:ERR162872 AM:i:37 NM:i:3 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR013140.6157908 99 17 3994 37 108M = 4176 276 TTAGGGCTGATATTCCACACACCCGCTACACTCCTTCTTAGGGCTGATATTCCACGCACCCGCTACACTCCTTCTTAGGGCTGATATTCCACGCACCTGCTACACTCC @ABDGGHJGIFGFGIJJFJFKGKK@JKHGKGKJKLIKLHHIJJJLJLHIHIELKHAKLHLLAKLIHLHJKLJIKLDFEIEALIGGFH?DAJC7GHEBEFDIDAD@A<; X0:i:1 X1:i:0 MD:Z:108 RG:Z:ERR013140 AM:i:0 NM:i:0 SM:i:37 MQ:i:23 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ diff --git a/test/mpileup/mpileup.10.out b/test/mpileup/mpileup.10.out new file mode 100644 index 0000000..1436904 --- /dev/null +++ b/test/mpileup/mpileup.10.out @@ -0,0 +1,70 @@ +##fileformat=VCFv4.2 +##FILTER= +##contig= +##ALT= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##FORMAT= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT SAMPLE1b HG00100 SAMPLE1a SAMPLE2 SAMPLE3 +17 100 . C <*> 0 . DP=16;I16=15,0,0,0,609,26637,0,0,838,48482,0,0,310,7132,0,0;QS=5,0;MQ0F=0 PL 0,3,19 0,6,78 0,12,128 0,9,108 0,15,134 +17 101 . C <*> 0 . DP=16;I16=15,0,0,0,587,25433,0,0,838,48482,0,0,309,7011,0,0;QS=5,0;MQ0F=0 PL 0,3,22 0,6,79 0,12,123 0,9,99 0,15,132 +17 102 . C <*> 0 . DP=16;I16=15,0,0,0,621,27715,0,0,838,48482,0,0,308,6904,0,0;QS=5,0;MQ0F=0 PL 0,3,20 0,6,78 0,12,129 0,9,111 0,15,139 +17 103 . T <*> 0 . DP=16;I16=14,0,0,0,612,28790,0,0,809,47641,0,0,301,6775,0,0;QS=4,0;MQ0F=0 PL 0,0,0 0,6,79 0,12,131 0,9,108 0,15,147 +17 104 . G <*> 0 . DP=16;I16=13,0,0,0,546,24526,0,0,780,46800,0,0,273,6009,0,0;QS=4,0;MQ0F=0 PL 0,0,0 0,6,78 0,12,123 0,6,89 0,15,133 +17 105 . G <*> 0 . DP=17;I16=15,0,0,0,542,21886,0,0,869,51241,0,0,295,6507,0,0;QS=5,0;MQ0F=0 PL 0,3,26 0,6,77 0,12,106 0,9,97 0,15,125 +17 106 . G <*> 0 . DP=17;I16=15,0,0,0,570,23834,0,0,869,51241,0,0,277,5851,0,0;QS=5,0;MQ0F=0 PL 0,6,43 0,6,75 0,12,130 0,6,85 0,15,124 +17 107 . C <*> 0 . DP=17;I16=15,0,0,0,614,26864,0,0,869,51241,0,0,291,6299,0,0;QS=5,0;MQ0F=0 PL 0,3,30 0,6,77 0,12,130 0,9,108 0,15,136 +17 108 . C <*> 0 . DP=17;I16=15,0,0,0,615,27183,0,0,869,51241,0,0,288,6170,0,0;QS=5,0;MQ0F=0 PL 0,3,30 0,6,78 0,12,128 0,9,108 0,15,135 +17 109 . T <*> 0 . DP=17;I16=15,0,0,0,664,31304,0,0,869,51241,0,0,285,6059,0,0;QS=5,0;MQ0F=0 PL 0,3,33 0,6,77 0,12,133 0,9,110 0,15,150 +17 110 . G <*> 0 . DP=17;I16=15,0,0,0,624,28074,0,0,869,51241,0,0,282,5966,0,0;QS=5,0;MQ0F=0 PL 0,3,35 0,6,78 0,12,130 0,9,104 0,15,136 +17 111 . G <*> 0 . DP=17;I16=14,0,0,0,514,21894,0,0,809,47641,0,0,250,5124,0,0;QS=5,0;MQ0F=0 PL 0,6,45 0,6,75 0,12,92 0,6,88 0,12,118 +17 112 . C <*> 0 . DP=17;I16=15,0,0,0,600,26654,0,0,869,51241,0,0,274,5738,0,0;QS=5,0;MQ0F=0 PL 0,3,30 0,6,77 0,12,129 0,9,95 0,15,135 +17 113 . A <*> 0 . DP=17;I16=14,0,0,0,575,25583,0,0,840,50400,0,0,244,4978,0,0;QS=5,0;MQ0F=0 PL 0,3,30 0,6,71 0,12,120 0,6,87 0,15,139 +17 114 . C <*> 0 . DP=17;I16=15,0,0,0,595,25667,0,0,869,51241,0,0,264,5486,0,0;QS=5,0;MQ0F=0 PL 0,3,33 0,6,75 0,12,118 0,9,103 0,15,133 +17 115 . C <*> 0 . DP=19;I16=16,0,0,0,635,27881,0,0,929,54841,0,0,252,5086,0,0;QS=5,0;MQ0F=0 PL 0,6,43 0,6,80 0,12,123 0,6,89 0,18,147 +17 116 . A <*> 0 . DP=19;I16=15,1,0,0,653,29009,0,0,929,54841,0,0,231,4637,0,0;QS=5,0;MQSB=1;MQ0F=0 PL 0,3,37 0,6,75 0,12,121 0,6,90 0,21,175 +17 117 . G <*> 0 . DP=19;I16=15,1,0,0,642,27956,0,0,929,54841,0,0,227,4535,0,0;QS=5,0;MQSB=1;MQ0F=0 PL 0,3,37 0,6,77 0,12,117 0,6,85 0,21,177 +17 118 . G <*> 0 . DP=19;I16=15,1,0,0,599,25205,0,0,898,52082,0,0,243,4897,0,0;QS=5,0;MQSB=1;MQ0F=0 PL 0,6,43 0,6,77 0,12,116 0,3,60 0,21,162 +17 119 . G <*> 0 . DP=18;I16=15,1,0,0,591,24995,0,0,898,52082,0,0,243,4977,0,0;QS=5,0;MQSB=1;MQ0F=0 PL 0,3,38 0,6,78 0,12,114 0,6,73 0,21,160 +17 120 . A <*> 0 . DP=18;I16=15,1,0,0,634,27744,0,0,898,52082,0,0,239,4893,0,0;QS=5,0;MQSB=1;MQ0F=0 PL 0,3,41 0,6,75 0,12,116 0,6,83 0,21,171 +17 121 . G <*> 0 . DP=18;I16=15,1,0,0,631,27499,0,0,898,52082,0,0,235,4829,0,0;QS=5,0;MQSB=1;MQ0F=0 PL 0,3,39 0,6,80 0,12,121 0,6,80 0,21,168 +17 122 . C <*> 0 . DP=19;I16=16,1,0,0,675,29543,0,0,958,55682,0,0,231,4785,0,0;QS=5,0;MQSB=1;MQ0F=0 PL 0,3,40 0,6,78 0,12,119 0,9,99 0,21,178 +17 123 . T <*> 0 . DP=17;I16=14,1,0,0,624,28628,0,0,838,48482,0,0,230,4760,0,0;QS=5,0;MQSB=1;MQ0F=0 PL 0,3,39 0,6,75 0,9,98 0,9,112 0,18,166 +17 124 . T <*> 0 . DP=17;I16=15,1,0,0,567,23061,0,0,867,49323,0,0,254,5378,0,0;QS=5,0;MQSB=1;MQ0F=0 PL 0,6,33 0,6,70 0,9,89 0,9,104 0,18,154 +17 125 . A <*> 0 . DP=16;I16=13,1,0,0,544,23440,0,0,778,44882,0,0,228,4714,0,0;QS=5,0;MQSB=1;MQ0F=0 PL 0,3,38 0,6,72 0,6,63 0,9,104 0,18,162 +17 126 . A <*> 0 . DP=16;I16=14,1,0,0,577,24833,0,0,807,45723,0,0,252,5318,0,0;QS=5,0;MQSB=1;MQ0F=0 PL 0,6,50 0,6,72 0,6,67 0,9,107 0,18,174 +17 127 . C <*> 0 . DP=16;I16=14,1,0,0,573,24303,0,0,807,45723,0,0,251,5315,0,0;QS=5,0;MQSB=1;MQ0F=0 PL 0,6,46 0,6,69 0,6,75 0,9,109 0,18,160 +17 128 . A <*> 0 . DP=16;I16=14,1,0,0,601,26205,0,0,807,45723,0,0,250,5330,0,0;QS=5,0;MQSB=1;MQ0F=0 PL 0,6,59 0,6,74 0,6,72 0,9,111 0,18,162 +17 129 . A <*> 0 . DP=15;I16=13,1,0,0,576,25510,0,0,747,42123,0,0,250,5362,0,0;QS=5,0;MQSB=1;MQ0F=0 PL 0,6,59 0,6,72 0,6,73 0,9,113 0,15,159 +17 130 . A <*> 0 . DP=15;I16=13,1,0,0,570,24774,0,0,747,42123,0,0,250,5410,0,0;QS=5,0;MQSB=1;MQ0F=0 PL 0,6,60 0,6,76 0,6,68 0,9,113 0,15,152 +17 131 . C <*> 0 . DP=14;I16=12,1,0,0,530,22844,0,0,718,41282,0,0,224,4798,0,0;QS=5,0;MQSB=1;MQ0F=0 PL 0,3,38 0,6,77 0,6,71 0,9,110 0,15,147 +17 132 . A <*> 0 . DP=14;I16=12,1,0,0,552,24766,0,0,718,41282,0,0,223,4825,0,0;QS=5,0;MQSB=1;MQ0F=0 PL 0,3,42 0,6,73 0,6,75 0,9,110 0,15,151 +17 133 . T <*> 0 . DP=13;I16=11,2,0,0,512,20224,0,0,718,41282,0,0,248,5490,0,0;QS=5,0;MQSB=0.590909;MQ0F=0 PL 0,3,38 0,6,74 0,6,71 0,9,105 0,15,150 +17 134 . C <*> 0 . DP=13;I16=11,2,0,0,526,21368,0,0,718,41282,0,0,248,5542,0,0;QS=5,0;MQSB=0.590909;MQ0F=0 PL 0,3,41 0,6,79 0,6,77 0,9,105 0,15,152 +17 135 . T <*> 0 . DP=13;I16=11,2,0,0,523,21213,0,0,718,41282,0,0,248,5606,0,0;QS=5,0;MQSB=0.590909;MQ0F=0 PL 0,3,40 0,6,78 0,6,77 0,9,106 0,15,156 +17 136 . G <*> 0 . DP=13;I16=11,2,0,0,495,19137,0,0,718,41282,0,0,249,5681,0,0;QS=5,0;MQSB=0.590909;MQ0F=0 PL 0,3,39 0,6,79 0,6,71 0,9,105 0,15,134 +17 137 . T <*> 0 . DP=13;I16=11,2,0,0,494,18984,0,0,718,41282,0,0,251,5767,0,0;QS=5,0;MQSB=0.590909;MQ0F=0 PL 0,3,39 0,6,73 0,6,69 0,9,104 0,15,139 +17 138 . C <*> 0 . DP=13;I16=11,2,0,0,504,19886,0,0,718,41282,0,0,252,5816,0,0;QS=5,0;MQSB=0.590909;MQ0F=0 PL 0,3,40 0,6,79 0,6,71 0,9,108 0,15,142 +17 139 . C <*> 0 . DP=13;I16=11,2,0,0,479,17977,0,0,718,41282,0,0,252,5830,0,0;QS=5,0;MQSB=0.590909;MQ0F=0 PL 0,3,37 0,6,76 0,6,62 0,9,106 0,15,143 +17 140 . A <*> 0 . DP=13;I16=11,2,0,0,509,20051,0,0,718,41282,0,0,251,5809,0,0;QS=5,0;MQSB=0.590909;MQ0F=0 PL 0,3,39 0,6,73 0,6,70 0,9,107 0,15,153 +17 141 . G <*> 0 . DP=12;I16=10,2,0,0,452,17388,0,0,658,37682,0,0,250,5750,0,0;QS=5,0;MQSB=0.6;MQ0F=0 PL 0,3,36 0,6,79 0,3,34 0,9,108 0,15,142 +17 142 . C <*> 0 . DP=12;I16=10,2,0,0,426,15624,0,0,658,37682,0,0,249,5701,0,0;QS=5,0;MQSB=0.6;MQ0F=0 PL 0,3,39 0,6,78 0,3,37 0,9,97 0,15,129 +17 143 . G <*> 0 . DP=12;I16=9,2,0,0,353,11735,0,0,598,34082,0,0,241,5613,0,0;QS=5,0;MQSB=0.611111;MQ0F=0 PL 0,3,33 0,6,60 0,3,36 0,9,95 0,12,97 +17 144 . A <*> 0 . DP=12;I16=10,2,0,0,443,16837,0,0,658,37682,0,0,246,5584,0,0;QS=5,0;MQSB=0.6;MQ0F=0 PL 0,3,33 0,6,75 0,3,41 0,9,105 0,15,129 +17 145 . A <*> 0 . DP=12;I16=10,2,0,0,451,17401,0,0,658,37682,0,0,244,5518,0,0;QS=5,0;MQSB=0.6;MQ0F=0 PL 0,3,42 0,6,74 0,3,34 0,9,106 0,15,138 +17 146 . T <*> 0 . DP=12;I16=10,2,0,0,439,16671,0,0,658,37682,0,0,242,5464,0,0;QS=5,0;MQSB=0.6;MQ0F=0 PL 0,3,37 0,6,73 0,3,41 0,9,103 0,15,128 +17 147 . A <*> 0 . DP=12;I16=10,2,0,0,444,16692,0,0,658,37682,0,0,240,5422,0,0;QS=5,0;MQSB=0.6;MQ0F=0 PL 0,3,40 0,6,70 0,3,41 0,9,99 0,15,140 +17 148 . C <*> 0 . DP=12;I16=10,2,0,0,465,18131,0,0,658,37682,0,0,237,5341,0,0;QS=5,0;MQSB=0.6;MQ0F=0 PL 0,3,39 0,6,77 0,3,41 0,9,106 0,15,146 +17 149 . C <*> 0 . DP=12;I16=10,2,0,0,433,16205,0,0,658,37682,0,0,233,5221,0,0;QS=5,0;MQSB=0.6;MQ0F=0 PL 0,3,38 0,6,77 0,3,18 0,9,109 0,15,140 +17 150 . T <*> 0 . DP=11;I16=9,2,0,0,436,17434,0,0,629,36841,0,0,230,5112,0,0;QS=5,0;MQSB=0.5;MQ0F=0 PL 0,3,36 0,6,76 0,3,40 0,6,84 0,15,152 diff --git a/test/mpileup/mpileup.11.out b/test/mpileup/mpileup.11.out new file mode 100644 index 0000000..e2ab38f --- /dev/null +++ b/test/mpileup/mpileup.11.out @@ -0,0 +1,4021 @@ +##fileformat=VCFv4.2 +##FILTER= +##contig= +##ALT= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##FORMAT= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT HG00102 +17 1 . A <*> 0 . DP=3;I16=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0;QS=0,0;MQ0F=0 PL 0,0,0 +17 2 . A <*> 0 . DP=3;I16=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0;QS=0,0;MQ0F=0 PL 0,0,0 +17 3 . G <*> 0 . DP=3;I16=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0;QS=0,0;MQ0F=0 PL 0,0,0 +17 4 . C <*> 0 . DP=3;I16=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0;QS=0,0;MQ0F=0 PL 0,0,0 +17 5 . T <*> 0 . DP=3;I16=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0;QS=0,0;MQ0F=0 PL 0,0,0 +17 6 . T <*> 0 . DP=3;I16=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0;QS=0,0;MQ0F=0 PL 0,0,0 +17 7 . C <*> 0 . DP=3;I16=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0;QS=0,0;MQ0F=0 PL 0,0,0 +17 8 . T <*> 0 . DP=3;I16=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0;QS=0,0;MQ0F=0 PL 0,0,0 +17 9 . C <*> 0 . DP=3;I16=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0;QS=0,0;MQ0F=0 PL 0,0,0 +17 10 . A <*> 0 . DP=3;I16=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0;QS=0,0;MQ0F=0 PL 0,0,0 +17 11 . C <*> 0 . DP=3;I16=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0;QS=0,0;MQ0F=0 PL 0,0,0 +17 12 . C <*> 0 . DP=3;I16=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0;QS=0,0;MQ0F=0 PL 0,0,0 +17 13 . C <*> 0 . DP=3;I16=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0;QS=0,0;MQ0F=0 PL 0,0,0 +17 14 . T <*> 0 . DP=3;I16=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0;QS=0,0;MQ0F=0 PL 0,0,0 +17 15 . G <*> 0 . DP=3;I16=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0;QS=0,0;MQ0F=0 PL 0,0,0 +17 16 . T <*> 0 . DP=3;I16=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0;QS=0,0;MQ0F=0 PL 0,0,0 +17 17 . T <*> 0 . DP=3;I16=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0;QS=0,0;MQ0F=0 PL 0,0,0 +17 18 . C <*> 0 . DP=3;I16=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0;QS=0,0;MQ0F=0 PL 0,0,0 +17 19 . C <*> 0 . DP=3;I16=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0;QS=0,0;MQ0F=0 PL 0,0,0 +17 20 . T <*> 0 . DP=3;I16=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0;QS=0,0;MQ0F=0 PL 0,0,0 +17 21 . G <*> 0 . DP=3;I16=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0;QS=0,0;MQ0F=0 PL 0,0,0 +17 22 . C <*> 0 . DP=3;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,0,0,0,0;QS=1,0;MQ0F=0 PL 0,3,33 +17 23 . A <*> 0 . DP=3;I16=1,0,0,0,39,1521,0,0,60,3600,0,0,1,1,0,0;QS=1,0;MQ0F=0 PL 0,3,39 +17 24 . T <*> 0 . DP=3;I16=1,0,0,0,37,1369,0,0,60,3600,0,0,2,4,0,0;QS=1,0;MQ0F=0 PL 0,3,37 +17 25 . A <*> 0 . DP=3;I16=1,0,0,0,38,1444,0,0,60,3600,0,0,3,9,0,0;QS=1,0;MQ0F=0 PL 0,3,38 +17 26 . G <*> 0 . DP=3;I16=1,0,0,0,38,1444,0,0,60,3600,0,0,4,16,0,0;QS=1,0;MQ0F=0 PL 0,3,38 +17 27 . A <*> 0 . DP=3;I16=1,0,0,0,40,1600,0,0,60,3600,0,0,5,25,0,0;QS=1,0;MQ0F=0 PL 0,3,40 +17 28 . T <*> 0 . DP=4;I16=2,0,0,0,72,2610,0,0,120,7200,0,0,6,36,0,0;QS=1,0;MQ0F=0 PL 0,6,66 +17 29 . A <*> 0 . DP=4;I16=2,0,0,0,76,2890,0,0,120,7200,0,0,8,50,0,0;QS=1,0;MQ0F=0 PL 0,6,69 +17 30 . A <*> 0 . DP=4;I16=2,0,0,0,80,3202,0,0,120,7200,0,0,10,68,0,0;QS=1,0;MQ0F=0 PL 0,6,73 +17 31 . T <*> 0 . DP=4;I16=2,0,0,0,77,2965,0,0,120,7200,0,0,12,90,0,0;QS=1,0;MQ0F=0 PL 0,6,70 +17 32 . T <*> 0 . DP=4;I16=2,0,0,0,76,2888,0,0,120,7200,0,0,14,116,0,0;QS=1,0;MQ0F=0 PL 0,6,69 +17 33 . G <*> 0 . DP=4;I16=2,0,0,0,77,2965,0,0,120,7200,0,0,16,146,0,0;QS=1,0;MQ0F=0 PL 0,6,70 +17 34 . C <*> 0 . DP=4;I16=2,0,0,0,79,3121,0,0,120,7200,0,0,18,180,0,0;QS=1,0;MQ0F=0 PL 0,6,72 +17 35 . A <*> 0 . DP=5;I16=3,0,0,0,111,4131,0,0,180,10800,0,0,20,218,0,0;QS=1,0;MQ0F=0 PL 0,9,93 +17 36 . T <*> 0 . DP=5;I16=3,0,0,0,115,4417,0,0,180,10800,0,0,23,261,0,0;QS=1,0;MQ0F=0 PL 0,9,96 +17 37 . G <*> 0 . DP=5;I16=3,0,0,0,117,4571,0,0,180,10800,0,0,26,310,0,0;QS=1,0;MQ0F=0 PL 0,9,98 +17 38 . A <*> 0 . DP=5;I16=3,0,0,0,120,4806,0,0,180,10800,0,0,29,365,0,0;QS=1,0;MQ0F=0 PL 0,9,100 +17 39 . C <*> 0 . DP=5;I16=3,0,0,0,113,4269,0,0,180,10800,0,0,32,426,0,0;QS=1,0;MQ0F=0 PL 0,9,95 +17 40 . A <*> 0 . DP=5;I16=3,0,0,0,119,4721,0,0,180,10800,0,0,35,493,0,0;QS=1,0;MQ0F=0 PL 0,9,99 +17 41 . A <*> 0 . DP=5;I16=3,0,0,0,123,5051,0,0,180,10800,0,0,38,566,0,0;QS=1,0;MQ0F=0 PL 0,9,103 +17 42 . T <*> 0 . DP=5;I16=3,0,0,0,118,4642,0,0,180,10800,0,0,41,645,0,0;QS=1,0;MQ0F=0 PL 0,9,98 +17 43 . T <*> 0 . DP=5;I16=3,0,0,0,121,4883,0,0,180,10800,0,0,44,730,0,0;QS=1,0;MQ0F=0 PL 0,9,101 +17 44 . G <*> 0 . DP=5;I16=3,0,0,0,120,4806,0,0,180,10800,0,0,47,821,0,0;QS=1,0;MQ0F=0 PL 0,9,100 +17 45 . C <*> 0 . DP=5;I16=3,0,0,0,116,4490,0,0,180,10800,0,0,50,918,0,0;QS=1,0;MQ0F=0 PL 0,9,97 +17 46 . C <*> 0 . DP=5;I16=3,0,0,0,123,5057,0,0,180,10800,0,0,53,1021,0,0;QS=1,0;MQ0F=0 PL 0,9,103 +17 47 . T <*> 0 . DP=5;I16=3,0,0,0,129,5549,0,0,180,10800,0,0,56,1130,0,0;QS=1,0;MQ0F=0 PL 0,9,108 +17 48 . T <*> 0 . DP=5;I16=3,0,0,0,123,5045,0,0,180,10800,0,0,58,1194,0,0;QS=1,0;MQ0F=0 PL 0,9,103 +17 49 . G <*> 0 . DP=5;I16=3,0,0,0,119,4725,0,0,180,10800,0,0,60,1262,0,0;QS=1,0;MQ0F=0 PL 0,9,99 +17 50 . T <*> 0 . DP=5;I16=3,0,0,0,120,4800,0,0,180,10800,0,0,62,1334,0,0;QS=1,0;MQ0F=0 PL 0,9,100 +17 51 . C <*> 0 . DP=5;I16=3,0,0,0,117,4601,0,0,180,10800,0,0,64,1410,0,0;QS=1,0;MQ0F=0 PL 0,9,99 +17 52 . C <*> 0 . DP=5;I16=3,0,0,0,120,4808,0,0,180,10800,0,0,66,1490,0,0;QS=1,0;MQ0F=0 PL 0,9,100 +17 53 . C <*> 0 . DP=5;I16=3,0,0,0,123,5069,0,0,180,10800,0,0,68,1574,0,0;QS=1,0;MQ0F=0 PL 0,9,103 +17 54 . T <*> 0 . DP=5;I16=3,0,0,0,129,5549,0,0,180,10800,0,0,69,1611,0,0;QS=1,0;MQ0F=0 PL 0,9,108 +17 55 . G <*> 0 . DP=5;I16=3,0,0,0,112,4206,0,0,180,10800,0,0,70,1650,0,0;QS=1,0;MQ0F=0 PL 0,9,94 +17 56 . C <*> 0 . DP=5;I16=3,0,0,0,123,5049,0,0,180,10800,0,0,71,1691,0,0;QS=1,0;MQ0F=0 PL 0,9,103 +17 57 . T <*> 0 . DP=5;I16=3,0,0,0,131,5721,0,0,180,10800,0,0,72,1734,0,0;QS=1,0;MQ0F=0 PL 0,9,109 +17 58 . G <*> 0 . DP=5;I16=3,0,0,0,123,5045,0,0,180,10800,0,0,73,1779,0,0;QS=1,0;MQ0F=0 PL 0,9,103 +17 59 . A <*> 0 . DP=5;I16=3,0,0,0,126,5294,0,0,180,10800,0,0,74,1826,0,0;QS=1,0;MQ0F=0 PL 0,9,105 +17 60 . A <*> 0 . DP=5;I16=3,0,0,0,131,5721,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,109 +17 61 . T <*> 0 . DP=5;I16=3,0,0,0,123,5045,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,103 +17 62 . G <*> 0 . DP=6;I16=4,0,0,0,153,5923,0,0,240,14400,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,12,119 +17 63 . T <*> 0 . DP=6;I16=4,0,0,0,157,6187,0,0,240,14400,0,0,76,1876,0,0;QS=1,0;MQ0F=0 PL 0,12,121 +17 64 . G <*> 0 . DP=6;I16=4,0,0,0,155,6039,0,0,240,14400,0,0,77,1879,0,0;QS=1,0;MQ0F=0 PL 0,12,120 +17 65 . C <*> 0 . DP=6;I16=4,0,0,0,161,6523,0,0,240,14400,0,0,78,1884,0,0;QS=1,0;MQ0F=0 PL 0,12,125 +17 66 . T <*> 0 . DP=6;I16=4,0,0,0,169,7155,0,0,240,14400,0,0,79,1891,0,0;QS=1,0;MQ0F=0 PL 0,12,130 +17 67 . C <*> 0 . DP=6;I16=4,0,0,0,160,6450,0,0,240,14400,0,0,80,1900,0,0;QS=1,0;MQ0F=0 PL 0,12,124 +17 68 . T <*> 0 . DP=6;I16=4,0,0,0,166,6918,0,0,240,14400,0,0,81,1911,0,0;QS=1,0;MQ0F=0 PL 0,12,128 +17 69 . G <*> 0 . DP=6;I16=4,0,0,0,154,5972,0,0,240,14400,0,0,82,1924,0,0;QS=1,0;MQ0F=0 PL 0,12,119 +17 70 . G <*> 0 . DP=6;I16=4,0,0,0,152,5884,0,0,240,14400,0,0,83,1939,0,0;QS=1,0;MQ0F=0 PL 0,12,118 +17 71 . G <*> 0 . DP=6;I16=3,0,0,0,121,4899,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,102 +17 72 . G <*> 0 . DP=6;I16=3,0,0,0,121,4961,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,102 +17 73 . T <*> 0 . DP=6;I16=4,0,0,0,156,6094,0,0,240,14400,0,0,86,1996,0,0;QS=1,0;MQ0F=0 PL 0,12,120 +17 74 . C <*> 0 . DP=6;I16=4,0,0,0,154,5938,0,0,240,14400,0,0,87,2019,0,0;QS=1,0;MQ0F=0 PL 0,12,118 +17 75 . T <*> 0 . DP=6;I16=4,0,0,0,165,6859,0,0,240,14400,0,0,88,2044,0,0;QS=1,0;MQ0F=0 PL 0,12,128 +17 76 . C <*> 0 . DP=6;I16=4,0,0,0,163,6655,0,0,240,14400,0,0,89,2071,0,0;QS=1,0;MQ0F=0 PL 0,12,125 +17 77 . T <*> 0 . DP=6;I16=4,0,0,0,170,7266,0,0,240,14400,0,0,90,2100,0,0;QS=1,0;MQ0F=0 PL 0,12,131 +17 78 . G <*> 0 . DP=6;I16=4,0,0,0,164,6732,0,0,240,14400,0,0,91,2131,0,0;QS=1,0;MQ0F=0 PL 0,12,126 +17 79 . G <*> 0 . DP=6;I16=4,0,0,0,164,6742,0,0,240,14400,0,0,92,2164,0,0;QS=1,0;MQ0F=0 PL 0,12,126 +17 80 . G <*> 0 . DP=6;I16=4,0,0,0,166,6964,0,0,240,14400,0,0,93,2199,0,0;QS=1,0;MQ0F=0 PL 0,12,129 +17 81 . G <*> 0 . DP=6;I16=4,0,0,0,157,6277,0,0,240,14400,0,0,94,2236,0,0;QS=1,0;MQ0F=0 PL 0,12,123 +17 82 . T <*> 0 . DP=6;I16=4,0,0,0,140,4934,0,0,240,14400,0,0,95,2275,0,0;QS=1,0;MQ0F=0 PL 0,12,108 +17 83 . C <*> 0 . DP=6;I16=4,0,0,0,160,6402,0,0,240,14400,0,0,96,2316,0,0;QS=1,0;MQ0F=0 PL 0,12,122 +17 84 . T <*> 0 . DP=6;I16=4,0,0,0,170,7266,0,0,240,14400,0,0,97,2359,0,0;QS=1,0;MQ0F=0 PL 0,12,131 +17 85 . C <*> 0 . DP=6;I16=4,0,0,0,170,7234,0,0,240,14400,0,0,98,2404,0,0;QS=1,0;MQ0F=0 PL 0,12,131 +17 86 . A <*> 0 . DP=6;I16=4,0,0,0,165,6813,0,0,240,14400,0,0,99,2451,0,0;QS=1,0;MQ0F=0 PL 0,12,126 +17 87 . C <*> 0 . DP=6;I16=4,0,0,0,163,6653,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQ0F=0 PL 0,12,125 +17 88 . C <*> 0 . DP=6;I16=4,0,0,0,169,7153,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQ0F=0 PL 0,12,130 +17 89 . C <*> 0 . DP=6;I16=4,0,0,0,170,7236,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQ0F=0 PL 0,12,131 +17 90 . A <*> 0 . DP=5;I16=4,0,0,0,164,6730,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQ0F=0 PL 0,12,126 +17 91 . C <*> 0 . DP=5;I16=4,0,0,0,155,6087,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQ0F=0 PL 0,12,120 +17 92 . G <*> 0 . DP=5;I16=4,0,0,0,107,2997,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQ0F=0 PL 0,12,84 +17 93 . A <*> 0 . DP=5;I16=5,0,0,0,203,8339,0,0,300,18000,0,0,100,2500,0,0;QS=1,0;MQ0F=0 PL 0,15,145 +17 94 . C <*> 0 . DP=5;I16=5,0,0,0,189,7181,0,0,300,18000,0,0,101,2501,0,0;QS=1,0;MQ0F=0 PL 0,15,135 +17 95 . C <*> 0 . DP=5;I16=5,0,0,0,188,7166,0,0,300,18000,0,0,102,2504,0,0;QS=1,0;MQ0F=0 PL 0,15,135 +17 96 . A <*> 0 . DP=5;I16=5,0,0,0,188,7130,0,0,300,18000,0,0,103,2509,0,0;QS=1,0;MQ0F=0 PL 0,15,134 +17 97 . A <*> 0 . DP=5;I16=5,0,0,0,204,8350,0,0,300,18000,0,0,104,2516,0,0;QS=1,0;MQ0F=0 PL 0,15,145 +17 98 . C <*> 0 . DP=5;I16=5,0,0,0,186,6926,0,0,300,18000,0,0,104,2476,0,0;QS=1,0;MQ0F=0 PL 0,15,131 +17 99 . T <*> 0 . DP=5;I16=5,0,0,0,216,9340,0,0,300,18000,0,0,104,2440,0,0;QS=1,0;MQ0F=0 PL 0,15,153 +17 100 . C <*> 0 . DP=5;I16=5,0,0,0,188,7146,0,0,300,18000,0,0,104,2408,0,0;QS=1,0;MQ0F=0 PL 0,15,134 +17 101 . C <*> 0 . DP=5;I16=5,0,0,0,187,7005,0,0,300,18000,0,0,104,2380,0,0;QS=1,0;MQ0F=0 PL 0,15,132 +17 102 . C <*> 0 . DP=5;I16=5,0,0,0,197,7767,0,0,300,18000,0,0,104,2356,0,0;QS=1,0;MQ0F=0 PL 0,15,139 +17 103 . T <*> 0 . DP=5;I16=5,0,0,0,207,8593,0,0,300,18000,0,0,104,2336,0,0;QS=1,0;MQ0F=0 PL 0,15,147 +17 104 . G <*> 0 . DP=5;I16=5,0,0,0,187,7033,0,0,300,18000,0,0,103,2271,0,0;QS=1,0;MQ0F=0 PL 0,15,133 +17 105 . G <*> 0 . DP=5;I16=5,0,0,0,176,6234,0,0,300,18000,0,0,102,2212,0,0;QS=1,0;MQ0F=0 PL 0,15,125 +17 106 . G <*> 0 . DP=5;I16=5,0,0,0,170,6050,0,0,300,18000,0,0,101,2159,0,0;QS=1,0;MQ0F=0 PL 0,15,124 +17 107 . C <*> 0 . DP=5;I16=5,0,0,0,190,7310,0,0,300,18000,0,0,100,2112,0,0;QS=1,0;MQ0F=0 PL 0,15,136 +17 108 . C <*> 0 . DP=5;I16=5,0,0,0,190,7266,0,0,300,18000,0,0,99,2071,0,0;QS=1,0;MQ0F=0 PL 0,15,135 +17 109 . T <*> 0 . DP=5;I16=5,0,0,0,212,8996,0,0,300,18000,0,0,98,2036,0,0;QS=1,0;MQ0F=0 PL 0,15,150 +17 110 . G <*> 0 . DP=5;I16=5,0,0,0,192,7394,0,0,300,18000,0,0,97,2007,0,0;QS=1,0;MQ0F=0 PL 0,15,136 +17 111 . G <*> 0 . DP=5;I16=4,0,0,0,153,5885,0,0,240,14400,0,0,78,1646,0,0;QS=1,0;MQ0F=0 PL 0,12,118 +17 112 . C <*> 0 . DP=5;I16=5,0,0,0,188,7158,0,0,300,18000,0,0,93,1871,0,0;QS=1,0;MQ0F=0 PL 0,15,135 +17 113 . A <*> 0 . DP=5;I16=5,0,0,0,196,7732,0,0,300,18000,0,0,91,1815,0,0;QS=1,0;MQ0F=0 PL 0,15,139 +17 114 . C <*> 0 . DP=5;I16=5,0,0,0,188,7086,0,0,300,18000,0,0,89,1767,0,0;QS=1,0;MQ0F=0 PL 0,15,133 +17 115 . C <*> 0 . DP=7;I16=6,0,0,0,224,8432,0,0,360,21600,0,0,87,1727,0,0;QS=1,0;MQ0F=0 PL 0,18,147 +17 116 . A <*> 0 . DP=7;I16=6,1,0,0,255,9511,0,0,389,22441,0,0,88,1700,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,175 +17 117 . G <*> 0 . DP=7;I16=6,1,0,0,256,9462,0,0,389,22441,0,0,88,1684,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,177 +17 118 . G <*> 0 . DP=7;I16=6,1,0,0,237,8065,0,0,389,22441,0,0,88,1680,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,162 +17 119 . G <*> 0 . DP=7;I16=6,1,0,0,223,7487,0,0,389,22441,0,0,87,1637,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,160 +17 120 . A <*> 0 . DP=7;I16=6,1,0,0,247,8873,0,0,389,22441,0,0,86,1604,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,171 +17 121 . G <*> 0 . DP=7;I16=6,1,0,0,239,8281,0,0,389,22441,0,0,85,1581,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,168 +17 122 . C <*> 0 . DP=7;I16=6,1,0,0,261,9859,0,0,389,22441,0,0,84,1568,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,178 +17 123 . T <*> 0 . DP=6;I16=5,1,0,0,230,9030,0,0,329,18841,0,0,84,1564,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,166 +17 124 . T <*> 0 . DP=6;I16=5,1,0,0,212,7558,0,0,329,18841,0,0,84,1568,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,154 +17 125 . A <*> 0 . DP=6;I16=5,1,0,0,218,7960,0,0,329,18841,0,0,84,1580,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,162 +17 126 . A <*> 0 . DP=6;I16=5,1,0,0,233,9117,0,0,329,18841,0,0,84,1600,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,174 +17 127 . C <*> 0 . DP=6;I16=5,1,0,0,220,8134,0,0,329,18841,0,0,84,1628,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,160 +17 128 . A <*> 0 . DP=6;I16=5,1,0,0,222,8300,0,0,329,18841,0,0,84,1664,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,162 +17 129 . A <*> 0 . DP=5;I16=4,1,0,0,201,8125,0,0,269,15241,0,0,85,1707,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,159 +17 130 . A <*> 0 . DP=5;I16=4,1,0,0,195,7685,0,0,269,15241,0,0,86,1756,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,152 +17 131 . C <*> 0 . DP=5;I16=4,1,0,0,186,6968,0,0,269,15241,0,0,87,1811,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,147 +17 132 . A <*> 0 . DP=5;I16=4,1,0,0,194,7534,0,0,269,15241,0,0,88,1872,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,151 +17 133 . T <*> 0 . DP=5;I16=4,1,0,0,197,7785,0,0,269,15241,0,0,89,1939,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,150 +17 134 . C <*> 0 . DP=5;I16=4,1,0,0,192,7410,0,0,269,15241,0,0,90,2012,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,152 +17 135 . T <*> 0 . DP=5;I16=4,1,0,0,192,7504,0,0,269,15241,0,0,91,2091,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,156 +17 136 . G <*> 0 . DP=5;I16=4,1,0,0,170,5902,0,0,269,15241,0,0,93,2175,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,134 +17 137 . T <*> 0 . DP=5;I16=4,1,0,0,179,6559,0,0,269,15241,0,0,96,2264,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,139 +17 138 . C <*> 0 . DP=5;I16=4,1,0,0,175,6329,0,0,269,15241,0,0,98,2310,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,142 +17 139 . C <*> 0 . DP=5;I16=4,1,0,0,174,6232,0,0,269,15241,0,0,100,2364,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,143 +17 140 . A <*> 0 . DP=5;I16=4,1,0,0,192,7430,0,0,269,15241,0,0,101,2375,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,153 +17 141 . G <*> 0 . DP=5;I16=4,1,0,0,175,6313,0,0,269,15241,0,0,101,2341,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,142 +17 142 . C <*> 0 . DP=5;I16=4,1,0,0,156,5110,0,0,269,15241,0,0,101,2311,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,129 +17 143 . G <*> 0 . DP=5;I16=3,1,0,0,118,3692,0,0,209,11641,0,0,94,2236,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,97 +17 144 . A <*> 0 . DP=5;I16=4,1,0,0,167,5899,0,0,269,15241,0,0,101,2263,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,129 +17 145 . A <*> 0 . DP=5;I16=4,1,0,0,176,6526,0,0,269,15241,0,0,101,2245,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,138 +17 146 . T <*> 0 . DP=5;I16=4,1,0,0,163,5775,0,0,269,15241,0,0,101,2231,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,128 +17 147 . A <*> 0 . DP=5;I16=4,1,0,0,173,6177,0,0,269,15241,0,0,101,2221,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,140 +17 148 . C <*> 0 . DP=5;I16=4,1,0,0,183,6731,0,0,269,15241,0,0,101,2215,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,146 +17 149 . C <*> 0 . DP=5;I16=4,1,0,0,177,6309,0,0,269,15241,0,0,101,2213,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,140 +17 150 . T <*> 0 . DP=5;I16=4,1,0,0,193,7557,0,0,269,15241,0,0,101,2215,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,152 +17 151 . G <*> 0 . DP=5;I16=4,1,0,0,182,6682,0,0,269,15241,0,0,101,2221,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,144 +17 152 . C <*> 0 . DP=5;I16=4,1,0,0,187,7013,0,0,269,15241,0,0,101,2231,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,146 +17 153 . A <*> 0 . DP=5;I16=4,1,0,0,197,7771,0,0,269,15241,0,0,101,2245,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,153 +17 154 . T <*> 0 . DP=5;I16=4,1,0,0,179,6805,0,0,269,15241,0,0,101,2263,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,139 +17 155 . C <*> 0 . DP=5;I16=4,1,0,0,174,6156,0,0,269,15241,0,0,101,2285,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,139 +17 156 . C <*> 0 . DP=5;I16=4,1,0,0,190,7238,0,0,269,15241,0,0,101,2311,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,150 +17 157 . C <*> 0 . DP=5;I16=4,1,0,0,192,7384,0,0,269,15241,0,0,101,2341,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,149 +17 158 . T <*> 0 . DP=5;I16=4,1,0,0,205,8455,0,0,269,15241,0,0,101,2375,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,159 +17 159 . A <*> 0 . DP=6;I16=4,1,0,0,179,6513,0,0,269,15241,0,0,101,2413,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,135 +17 160 . G <*> 0 . DP=6;I16=5,1,0,0,187,6199,0,0,329,18841,0,0,102,2456,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,139 +17 161 . A <*> 0 . DP=6;I16=5,1,0,0,225,8479,0,0,329,18841,0,0,103,2505,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,162 +17 162 . A <*> 0 . DP=6;I16=5,1,0,0,232,9082,0,0,329,18841,0,0,103,2509,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,167 +17 163 . G <*> 0 . DP=5;I16=4,1,0,0,175,6497,0,0,269,15241,0,0,104,2516,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,138 +17 164 . T <*> 0 . DP=6;I16=5,1,0,0,184,6260,0,0,329,18841,0,0,105,2525,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,136 +17 165 . G <*> 0 . DP=6;I16=3,1,0,0,150,5646,0,0,209,11641,0,0,81,1911,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,122 +17 166 . A <*> 0 . DP=6;I16=4,1,0,0,194,7648,0,0,269,15241,0,0,84,1928,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,148 +17 167 . A <*> 0 . DP=6;I16=4,1,0,0,192,7414,0,0,269,15241,0,0,86,1948,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,147 +17 168 . G <*> 0 . DP=6;I16=5,1,0,0,186,6590,0,0,329,18841,0,0,113,2597,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,140 +17 169 . C <*> 0 . DP=6;I16=4,1,0,0,185,6895,0,0,269,15241,0,0,89,1951,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,145 +17 170 . C <*> 0 . DP=6;I16=5,1,0,0,193,6731,0,0,329,18841,0,0,115,2561,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,143 +17 171 . A <*> 0 . DP=6;I16=5,1,0,0,229,8851,0,0,329,18841,0,0,116,2552,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,166 +17 172 . C <*> 0 . DP=6;I16=4,1,0,0,169,5915,0,0,269,15241,0,0,109,2485,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,129 +17 173 . C <*> 0 . DP=6;I16=5,1,0,0,189,6439,0,0,329,18841,0,0,118,2552,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,146 +17 174 . G <*> 0 . DP=7;I16=5,1,0,0,168,5056,0,0,329,18841,0,0,109,2461,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,117 +17 175 . C <*> 0 . DP=7;I16=6,1,0,0,258,9650,0,0,389,22441,0,0,121,2577,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,175 +17 176 . C <*> 0 . DP=7;I16=6,1,0,0,222,7478,0,0,389,22441,0,0,123,2601,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,152 +17 177 . C <*> 0 . DP=7;I16=6,1,0,0,234,7984,0,0,389,22441,0,0,125,2633,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,158 +17 178 . A <*> 0 . DP=7;I16=6,1,0,0,252,9264,0,0,389,22441,0,0,127,2673,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,172 +17 179 . A <*> 0 . DP=7;I16=6,1,0,0,235,8463,0,0,389,22441,0,0,129,2721,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,170 +17 180 . A <*> 0 . DP=7;I16=5,1,0,0,197,6727,0,0,329,18841,0,0,125,2741,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,148 +17 181 . G <*> 0 . DP=7;I16=4,1,0,0,173,6131,0,0,269,15241,0,0,109,2503,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,138 +17 182 . A <*> 0 . DP=7;I16=6,1,0,0,226,7678,0,0,389,22441,0,0,135,2913,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,159 +17 183 . C <*> 0 . DP=7;I16=5,1,0,0,182,6012,0,0,329,18841,0,0,112,2368,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,139 +17 184 . A <*> 0 . DP=7;I16=6,1,0,0,233,8197,0,0,389,22441,0,0,139,3081,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,163 +17 185 . C <*> 0 . DP=7;I16=5,1,0,0,209,7363,0,0,329,18841,0,0,115,2501,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,160 +17 186 . G <*> 0 . DP=7;I16=5,1,0,0,171,5035,0,0,329,18841,0,0,116,2552,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,124 +17 187 . C <*> 0 . DP=7;I16=6,1,0,0,252,9238,0,0,389,22441,0,0,142,3234,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,172 +17 188 . C <*> 0 . DP=7;I16=6,1,0,0,239,8387,0,0,389,22441,0,0,143,3297,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,162 +17 189 . C <*> 0 . DP=7;I16=6,1,0,0,247,8819,0,0,389,22441,0,0,144,3366,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,167 +17 190 . A <*> 0 . DP=7;I16=5,1,0,0,219,8109,0,0,329,18841,0,0,118,2716,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,159 +17 191 . T <*> 0 . DP=7;I16=6,1,0,0,247,8853,0,0,389,22441,0,0,141,3273,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,169 +17 192 . G <*> 0 . DP=7;I16=6,1,0,0,221,7309,0,0,389,22441,0,0,139,3213,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,151 +17 193 . T <*> 0 . DP=7;I16=6,1,0,0,229,8027,0,0,389,22441,0,0,137,3161,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,157 +17 194 . C <*> 0 . DP=6;I16=5,1,0,0,190,6584,0,0,329,18841,0,0,136,3116,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,145 +17 195 . C <*> 0 . DP=6;I16=5,1,0,0,216,7916,0,0,329,18841,0,0,135,3077,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,160 +17 196 . A <*> 0 . DP=6;I16=5,1,0,0,183,6151,0,0,329,18841,0,0,134,3044,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,138 +17 197 . G <*> 0 . DP=6;I16=5,1,0,0,182,6006,0,0,329,18841,0,0,133,3017,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,134 +17 198 . C <*> 0 . DP=6;I16=5,1,0,0,224,8460,0,0,329,18841,0,0,132,2996,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,164 +17 199 . T <*> 0 . DP=6;I16=5,1,0,0,205,7417,0,0,329,18841,0,0,131,2981,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,154 +17 200 . T <*> 0 . DP=6;I16=5,1,0,0,212,7606,0,0,329,18841,0,0,129,2921,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,154 +17 201 . A <*> 0 . DP=6;I16=5,1,0,0,215,7815,0,0,329,18841,0,0,127,2865,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,157 +17 202 . A <*> 0 . DP=6;I16=5,1,0,0,222,8430,0,0,329,18841,0,0,125,2813,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,163 +17 203 . C <*> 0 . DP=6;I16=5,1,0,0,209,7439,0,0,329,18841,0,0,123,2765,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,153 +17 204 . C <*> 0 . DP=6;I16=5,1,0,0,220,8194,0,0,329,18841,0,0,121,2721,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,163 +17 205 . T <*> 0 . DP=6;I16=5,1,0,0,238,9464,0,0,329,18841,0,0,119,2681,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,173 +17 206 . G <*> 0 . DP=6;I16=5,1,0,0,194,6522,0,0,329,18841,0,0,117,2645,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,143 +17 207 . C <*> 0 . DP=6;I16=5,1,0,0,205,7051,0,0,329,18841,0,0,115,2613,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,151 +17 208 . A <*> 0 . DP=6;I16=5,1,0,0,204,7486,0,0,329,18841,0,0,113,2585,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,154 +17 209 . T <*> 0 . DP=6;I16=5,1,0,0,198,6710,0,0,329,18841,0,0,111,2561,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,146 +17 210 . C <*> 0 . DP=6;I16=5,1,0,0,203,6935,0,0,329,18841,0,0,109,2541,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,151 +17 211 . C <*> 0 . DP=6;I16=5,1,0,0,206,7092,0,0,329,18841,0,0,107,2525,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,153 +17 212 . C <*> 0 . DP=6;I16=5,1,0,0,207,7185,0,0,329,18841,0,0,104,2464,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,152 +17 213 . T <*> 0 . DP=6;I16=5,1,0,0,219,8179,0,0,329,18841,0,0,101,2409,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,165 +17 214 . A <*> 0 . DP=6;I16=4,1,0,0,143,4361,0,0,269,15241,0,0,76,1876,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,118 +17 215 . G <*> 0 . DP=5;I16=5,0,0,0,141,4397,0,0,300,18000,0,0,96,2316,0,0;QS=1,0;MQ0F=0 PL 0,15,105 +17 216 . A <*> 0 . DP=4;I16=3,0,0,0,95,3141,0,0,180,10800,0,0,70,1650,0,0;QS=1,0;MQ0F=0 PL 0,9,81 +17 217 . A <*> 0 . DP=4;I16=4,0,0,0,123,3969,0,0,240,14400,0,0,94,2236,0,0;QS=1,0;MQ0F=0 PL 0,12,97 +17 218 . G <*> 0 . DP=4;I16=4,0,0,0,143,5137,0,0,240,14400,0,0,93,2199,0,0;QS=1,0;MQ0F=0 PL 0,12,110 +17 219 . T <*> 0 . DP=4;I16=4,0,0,0,113,3379,0,0,240,14400,0,0,92,2164,0,0;QS=1,0;MQ0F=0 PL 0,12,89 +17 220 . G <*> 0 . DP=4;I16=3,0,0,0,95,3029,0,0,180,10800,0,0,66,1506,0,0;QS=1,0;MQ0F=0 PL 0,9,80 +17 221 . A <*> 0 . DP=4;I16=4,0,0,0,127,4371,0,0,240,14400,0,0,90,2100,0,0;QS=1,0;MQ0F=0 PL 0,12,101 +17 222 . A <*> 0 . DP=4;I16=3,0,0,0,79,2365,0,0,180,10800,0,0,64,1446,0,0;QS=1,0;MQ0F=0 PL 0,9,69 +17 223 . G <*> 0 . DP=4;I16=4,0,0,0,104,2810,0,0,240,14400,0,0,88,2044,0,0;QS=1,0;MQ0F=0 PL 0,12,81 +17 224 . G <*> 0 . DP=4;I16=4,0,0,0,89,2077,0,0,240,14400,0,0,87,2019,0,0;QS=1,0;MQ0F=0 PL 0,12,70 +17 225 . C <*> 0 . DP=4;I16=3,0,0,0,99,3305,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,83 +17 226 . A <*> 0 . DP=4;I16=3,0,0,0,98,3430,0,0,180,10800,0,0,60,1350,0,0;QS=1,0;MQ0F=0 PL 0,9,84 +17 227 . C <*> 0 . DP=4;I16=3,0,0,0,85,2649,0,0,180,10800,0,0,59,1331,0,0;QS=1,0;MQ0F=0 PL 0,9,73 +17 228 . C <*> 0 . DP=4;I16=4,0,0,0,121,3947,0,0,240,14400,0,0,83,1939,0,0;QS=1,0;MQ0F=0 PL 0,12,96 +17 229 . G <*> 0 . DP=4;I16=4,0,0,0,91,2097,0,0,240,14400,0,0,82,1924,0,0;QS=1,0;MQ0F=0 PL 0,12,70 +17 230 . C <*> 0 . DP=4;I16=4,0,0,0,128,4174,0,0,240,14400,0,0,81,1911,0,0;QS=1,0;MQ0F=0 PL 0,12,100 +17 231 . C <*> 0 . DP=4;I16=3,0,0,0,97,3181,0,0,180,10800,0,0,55,1275,0,0;QS=1,0;MQ0F=0 PL 0,9,82 +17 232 . C <*> 0 . DP=5;I16=4,0,0,0,129,4277,0,0,240,14400,0,0,54,1266,0,0;QS=1,0;MQ0F=0 PL 0,12,101 +17 233 . A <*> 0 . DP=5;I16=5,0,0,0,166,5636,0,0,300,18000,0,0,79,1885,0,0;QS=1,0;MQ0F=0 PL 0,15,119 +17 234 . A <*> 0 . DP=5;I16=5,0,0,0,170,5930,0,0,300,18000,0,0,79,1883,0,0;QS=1,0;MQ0F=0 PL 0,15,123 +17 235 . A <*> 0 . DP=5;I16=4,0,0,0,143,5181,0,0,240,14400,0,0,54,1260,0,0;QS=1,0;MQ0F=0 PL 0,12,111 +17 236 . G <*> 0 . DP=5;I16=5,0,0,0,141,4187,0,0,300,18000,0,0,77,1795,0,0;QS=1,0;MQ0F=0 PL 0,15,103 +17 237 . A <*> 0 . DP=4;I16=3,0,0,0,109,4005,0,0,180,10800,0,0,52,1134,0,0;QS=1,0;MQ0F=0 PL 0,9,92 +17 238 . C <*> 0 . DP=4;I16=4,0,0,0,104,2856,0,0,240,14400,0,0,77,1727,0,0;QS=1,0;MQ0F=0 PL 0,12,82 +17 239 . A <*> 0 . DP=4;I16=4,0,0,0,138,4886,0,0,240,14400,0,0,77,1699,0,0;QS=1,0;MQ0F=0 PL 0,12,108 +17 240 . C <*> 0 . DP=4;I16=4,0,0,0,136,4700,0,0,240,14400,0,0,76,1626,0,0;QS=1,0;MQ0F=0 PL 0,12,106 +17 241 . G <*> 0 . DP=4;I16=3,0,0,0,69,1673,0,0,180,10800,0,0,52,1030,0,0;QS=1,0;MQ0F=0 PL 0,9,59 +17 242 . C <*> 0 . DP=4;I16=4,0,0,0,119,3707,0,0,240,14400,0,0,74,1498,0,0;QS=1,0;MQ0F=0 PL 0,12,94 +17 243 . C <*> 0 . DP=4;I16=4,0,0,0,134,4530,0,0,240,14400,0,0,73,1443,0,0;QS=1,0;MQ0F=0 PL 0,12,104 +17 244 . C <*> 0 . DP=4;I16=4,0,0,0,136,4690,0,0,240,14400,0,0,72,1394,0,0;QS=1,0;MQ0F=0 PL 0,12,106 +17 245 . A <*> 0 . DP=4;I16=4,0,0,0,150,5630,0,0,240,14400,0,0,71,1351,0,0;QS=1,0;MQ0F=0 PL 0,12,115 +17 246 . T <*> 0 . DP=4;I16=4,0,0,0,124,4014,0,0,240,14400,0,0,70,1314,0,0;QS=1,0;MQ0F=0 PL 0,12,98 +17 247 . G <*> 0 . DP=4;I16=4,0,0,0,131,4411,0,0,240,14400,0,0,69,1283,0,0;QS=1,0;MQ0F=0 PL 0,12,103 +17 248 . T <*> 0 . DP=4;I16=4,0,0,0,147,5451,0,0,240,14400,0,0,68,1258,0,0;QS=1,0;MQ0F=0 PL 0,12,114 +17 249 . C <*> 0 . DP=4;I16=4,0,0,0,143,5279,0,0,240,14400,0,0,67,1239,0,0;QS=1,0;MQ0F=0 PL 0,12,112 +17 250 . C <*> 0 . DP=5;I16=4,1,0,0,179,6489,0,0,269,15241,0,0,65,1177,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,142 +17 251 . A <*> 0 . DP=5;I16=4,1,0,0,192,7424,0,0,269,15241,0,0,64,1124,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,148 +17 252 . G <*> 0 . DP=5;I16=3,1,0,0,146,5490,0,0,209,11641,0,0,51,937,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,121 +17 253 . C <*> 0 . DP=6;I16=4,2,0,0,202,7118,0,0,298,16082,0,0,62,1048,0,0;QS=1,0;MQSB=0;MQ0F=0 PL 0,18,155 +17 254 . T <*> 0 . DP=6;I16=4,2,0,0,214,7766,0,0,298,16082,0,0,62,1026,0,0;QS=1,0;MQSB=0;MQ0F=0 PL 0,18,164 +17 255 . T <*> 0 . DP=6;I16=4,2,0,0,213,7635,0,0,298,16082,0,0,62,1016,0,0;QS=1,0;MQSB=0;MQ0F=0 PL 0,18,161 +17 256 . A <*> 0 . DP=6;I16=4,2,0,0,220,8108,0,0,298,16082,0,0,62,1018,0,0;QS=1,0;MQSB=0;MQ0F=0 PL 0,18,166 +17 257 . T <*> 0 . DP=6;I16=4,2,0,0,221,8207,0,0,298,16082,0,0,62,1032,0,0;QS=1,0;MQSB=0;MQ0F=0 PL 0,18,168 +17 258 . T <*> 0 . DP=6;I16=4,2,0,0,206,7344,0,0,298,16082,0,0,61,1007,0,0;QS=1,0;MQSB=0;MQ0F=0 PL 0,18,155 +17 259 . C <*> 0 . DP=6;I16=4,2,0,0,222,8258,0,0,298,16082,0,0,60,992,0,0;QS=1,0;MQSB=0;MQ0F=0 PL 0,18,170 +17 260 . T <*> 0 . DP=5;I16=3,2,0,0,204,8334,0,0,238,12482,0,0,60,986,0,0;QS=1,0;MQSB=0;MQ0F=0 PL 0,15,156 +17 261 . G <*> 0 . DP=5;I16=3,2,0,0,160,5674,0,0,238,12482,0,0,60,988,0,0;QS=1,0;MQSB=0;MQ0F=0 PL 0,15,122 +17 262 . C <*> 0 . DP=6;I16=3,3,0,0,209,7403,0,0,298,16082,0,0,60,998,0,0;QS=1,0;MQSB=0.574341;MQ0F=0 PL 0,18,164 +17 263 . C <*> 0 . DP=6;I16=3,3,0,0,219,8063,0,0,298,16082,0,0,61,1017,0,0;QS=1,0;MQSB=0.574341;MQ0F=0 PL 0,18,168 +17 264 . C <*> 0 . DP=6;I16=3,3,0,0,226,8602,0,0,298,16082,0,0,62,1046,0,0;QS=1,0;MQSB=0.574341;MQ0F=0 PL 0,18,172 +17 265 . A <*> 0 . DP=5;I16=2,3,0,0,178,6994,0,0,238,12482,0,0,64,1084,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL 0,15,129 +17 266 . G <*> 0 . DP=5;I16=2,3,0,0,176,6264,0,0,238,12482,0,0,66,1130,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL 0,15,138 +17 267 . T <*> 0 . DP=5;I16=2,3,0,0,182,6638,0,0,238,12482,0,0,68,1184,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL 0,15,149 +17 268 . T <*> 0 . DP=5;I16=2,3,0,0,202,8164,0,0,238,12482,0,0,70,1246,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL 0,15,156 +17 269 . C <*> 0 . DP=5;I16=2,3,0,0,194,7534,0,0,238,12482,0,0,72,1316,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL 0,15,154 +17 270 . C <*> 0 . DP=5;I16=2,3,0,0,181,6567,0,0,238,12482,0,0,74,1394,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL 0,15,143 +17 271 . T <*> 0 . DP=5;I16=2,3,0,0,199,8023,0,0,238,12482,0,0,76,1480,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL 0,15,152 +17 272 . C <*> 0 . DP=5;I16=2,3,0,0,187,7025,0,0,238,12482,0,0,78,1574,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL 0,15,149 +17 273 . T <*> 0 . DP=5;I16=2,3,0,0,204,8344,0,0,238,12482,0,0,80,1676,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL 0,15,161 +17 274 . C <*> 0 . DP=5;I16=2,3,0,0,173,6067,0,0,238,12482,0,0,82,1786,0,0;QS=1,0;MQSB=0.333333;MQ0F=0 PL 0,15,144 +17 275 . C <*> 0 . DP=4;I16=1,3,0,0,161,6481,0,0,178,8882,0,0,85,1903,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,122 +17 276 . A <*> 0 . DP=4;I16=1,3,0,0,173,7535,0,0,178,8882,0,0,87,1975,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,124 +17 277 . G <*> 0 . DP=4;I16=1,3,0,0,162,6566,0,0,178,8882,0,0,89,2051,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,121 +17 278 . A <*> 0 . DP=4;I16=1,3,0,0,156,6110,0,0,178,8882,0,0,91,2131,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,121 +17 279 . A <*> 0 . DP=4;I16=1,3,0,0,165,6831,0,0,178,8882,0,0,92,2164,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,122 +17 280 . A <*> 0 . DP=4;I16=1,3,0,0,175,7665,0,0,178,8882,0,0,93,2199,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,129 +17 281 . G <*> 0 . DP=4;I16=1,3,0,0,161,6485,0,0,178,8882,0,0,94,2236,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,123 +17 282 . G <*> 0 . DP=4;I16=1,3,0,0,159,6351,0,0,178,8882,0,0,95,2275,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,119 +17 283 . C <*> 0 . DP=5;I16=1,3,0,0,165,6815,0,0,178,8882,0,0,96,2316,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,122 +17 284 . T <*> 0 . DP=5;I16=1,4,0,0,200,8016,0,0,238,12482,0,0,103,2395,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,144 +17 285 . G <*> 0 . DP=5;I16=1,4,0,0,188,7198,0,0,238,12482,0,0,105,2453,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,132 +17 286 . C <*> 0 . DP=5;I16=1,4,0,0,188,7234,0,0,238,12482,0,0,107,2515,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,134 +17 287 . A <*> 0 . DP=5;I16=1,4,0,0,184,7056,0,0,238,12482,0,0,109,2581,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,133 +17 288 . T <*> 0 . DP=5;I16=1,4,0,0,202,8180,0,0,238,12482,0,0,110,2600,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,146 +17 289 . G <*> 0 . DP=5;I16=1,4,0,0,190,7474,0,0,238,12482,0,0,111,2621,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,136 +17 290 . G <*> 0 . DP=5;I16=1,4,0,0,178,6538,0,0,238,12482,0,0,112,2644,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,126 +17 291 . T <*> 0 . DP=6;I16=1,4,0,0,194,7706,0,0,238,12482,0,0,100,2500,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,136 +17 292 . T <*> 0 . DP=6;I16=1,5,0,0,228,8746,0,0,298,16082,0,0,115,2697,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,156 +17 293 . G <*> 0 . DP=6;I16=1,4,0,0,199,7941,0,0,238,12482,0,0,102,2504,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,145 +17 294 . A <*> 0 . DP=6;I16=1,5,0,0,231,8927,0,0,298,16082,0,0,119,2765,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,161 +17 295 . C <*> 0 . DP=6;I16=1,5,0,0,232,9028,0,0,298,16082,0,0,121,2805,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,159 +17 296 . A <*> 0 . DP=6;I16=1,5,0,0,245,10011,0,0,298,16082,0,0,123,2849,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,169 +17 297 . C <*> 0 . DP=6;I16=1,5,0,0,230,8956,0,0,298,16082,0,0,125,2897,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,161 +17 298 . A <*> 0 . DP=7;I16=2,5,0,0,266,10190,0,0,358,19682,0,0,127,2949,0,0;QS=1,0;MQSB=0.6;MQ0F=0 PL 0,21,191 +17 299 . C <*> 0 . DP=7;I16=2,5,0,0,268,10372,0,0,358,19682,0,0,130,3006,0,0;QS=1,0;MQSB=0.6;MQ0F=0 PL 0,21,189 +17 300 . A <*> 0 . DP=7;I16=2,5,0,0,296,12578,0,0,358,19682,0,0,133,3069,0,0;QS=1,0;MQSB=0.6;MQ0F=0 PL 0,21,210 +17 301 . G <*> 0 . DP=7;I16=2,5,0,0,274,10742,0,0,358,19682,0,0,136,3138,0,0;QS=1,0;MQSB=0.6;MQ0F=0 PL 0,21,196 +17 302 . T <*> 0 . DP=7;I16=2,5,0,0,283,11451,0,0,358,19682,0,0,139,3213,0,0;QS=1,0;MQSB=0.6;MQ0F=0 PL 0,21,202 +17 302 . T TA 0 . INDEL;IDV=7;IMF=1;DP=7;I16=0,0,2,5,0,0,300,12862,0,0,358,19682,0,0,139,3213;QS=0,1;VDB=0.380378;SGB=-0.636426;MQSB=0.6;MQ0F=0 PL 201,21,0 +17 303 . G <*> 0 . DP=7;I16=2,5,0,0,280,11264,0,0,358,19682,0,0,144,3330,0,0;QS=1,0;MQSB=0.6;MQ0F=0 PL 0,21,195 +17 304 . C <*> 0 . DP=8;I16=2,6,0,0,304,11716,0,0,418,23282,0,0,146,3370,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL 0,24,200 +17 305 . C <*> 0 . DP=8;I16=2,6,0,0,318,12738,0,0,418,23282,0,0,149,3415,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL 0,24,211 +17 306 . T <*> 0 . DP=8;I16=2,6,0,0,320,12842,0,0,418,23282,0,0,152,3466,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL 0,24,217 +17 307 . G <*> 0 . DP=8;I16=2,6,0,0,303,11789,0,0,418,23282,0,0,154,3474,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL 0,24,203 +17 308 . C <*> 0 . DP=8;I16=2,6,0,0,266,8912,0,0,418,23282,0,0,156,3490,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL 0,24,185 +17 309 . G <*> 0 . DP=8;I16=2,6,0,0,304,11742,0,0,418,23282,0,0,158,3514,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL 0,24,205 +17 310 . A <*> 0 . DP=8;I16=2,6,0,0,316,12540,0,0,418,23282,0,0,160,3546,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL 0,24,217 +17 311 . C <*> 0 . DP=8;I16=2,6,0,0,315,12457,0,0,418,23282,0,0,162,3586,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL 0,24,210 +17 312 . A <*> 0 . DP=8;I16=2,6,0,0,325,13241,0,0,418,23282,0,0,164,3634,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL 0,24,218 +17 313 . A <*> 0 . DP=8;I16=2,6,0,0,319,12881,0,0,418,23282,0,0,166,3690,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL 0,24,215 +17 314 . A <*> 0 . DP=8;I16=2,6,0,0,340,14484,0,0,418,23282,0,0,168,3754,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL 0,24,227 +17 315 . G <*> 0 . DP=8;I16=2,6,0,0,335,14055,0,0,418,23282,0,0,170,3826,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL 0,24,225 +17 316 . C <*> 0 . DP=8;I16=2,6,0,0,329,13603,0,0,418,23282,0,0,171,3855,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL 0,24,224 +17 317 . T <*> 0 . DP=8;I16=2,6,0,0,305,12201,0,0,418,23282,0,0,172,3890,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL 0,24,206 +17 318 . G <*> 0 . DP=8;I16=2,6,0,0,307,12149,0,0,418,23282,0,0,173,3931,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL 0,24,208 +17 319 . A <*> 0 . DP=8;I16=1,6,0,0,279,11243,0,0,358,19682,0,0,162,3834,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,185 +17 320 . A <*> 0 . DP=8;I16=2,6,0,0,308,12130,0,0,418,23282,0,0,175,4031,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL 0,24,211 +17 321 . T <*> 0 . DP=8;I16=2,6,0,0,322,12994,0,0,418,23282,0,0,176,4090,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL 0,24,218 +17 322 . G <*> 0 . DP=9;I16=2,7,0,0,348,13586,0,0,478,26882,0,0,177,4155,0,0;QS=1,0;MQSB=0.714286;MQ0F=0 PL 0,27,223 +17 323 . C <*> 0 . DP=9;I16=1,7,0,0,320,12878,0,0,418,23282,0,0,170,4112,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,198 +17 324 . T <*> 0 . DP=11;I16=4,7,0,0,411,15559,0,0,598,34082,0,0,179,4203,0,0;QS=1,0;MQSB=0.763675;MQ0F=0 PL 0,33,255 +17 325 . A <*> 0 . DP=11;I16=4,7,0,0,413,15685,0,0,598,34082,0,0,181,4189,0,0;QS=1,0;MQSB=0.763675;MQ0F=0 PL 0,33,255 +17 326 . T <*> 0 . DP=11;I16=4,7,0,0,426,16994,0,0,598,34082,0,0,183,4187,0,0;QS=1,0;MQSB=0.763675;MQ0F=0 PL 0,33,255 +17 327 . C <*> 0 . DP=11;I16=4,7,0,0,418,16012,0,0,598,34082,0,0,185,4197,0,0;QS=1,0;MQSB=0.763675;MQ0F=0 PL 0,33,255 +17 328 . A <*> 0 . DP=11;I16=4,7,0,0,433,17075,0,0,598,34082,0,0,186,4170,0,0;QS=1,0;MQSB=0.763675;MQ0F=0 PL 0,33,255 +17 329 . T <*> 0 . DP=11;I16=4,7,0,0,444,18034,0,0,598,34082,0,0,187,4157,0,0;QS=1,0;MQSB=0.763675;MQ0F=0 PL 0,33,255 +17 330 . T <*> 0 . DP=11;I16=4,7,0,0,437,17577,0,0,598,34082,0,0,187,4107,0,0;QS=1,0;MQSB=0.763675;MQ0F=0 PL 0,33,255 +17 331 . T <*> 0 . DP=12;I16=5,7,0,0,425,15401,0,0,658,37682,0,0,187,4069,0,0;QS=1,0;MQSB=0.760054;MQ0F=0 PL 0,36,255 +17 332 . A <*> 0 . DP=11;I16=4,7,0,0,411,15645,0,0,598,34082,0,0,189,4043,0,0;QS=1,0;MQSB=0.763675;MQ0F=0 PL 0,33,255 +17 333 . A <*> 0 . DP=11;I16=4,7,0,0,405,15523,0,0,598,34082,0,0,191,4029,0,0;QS=1,0;MQSB=0.763675;MQ0F=0 PL 0,33,255 +17 334 . A <*> 0 . DP=11;I16=4,7,0,0,404,15090,0,0,598,34082,0,0,193,4027,0,0;QS=1,0;MQSB=0.763675;MQ0F=0 PL 0,33,255 +17 335 . A <*> 0 . DP=12;I16=4,7,0,0,382,13732,0,0,598,34082,0,0,195,4037,0,0;QS=1,0;MQSB=0.763675;MQ0F=0 PL 0,33,251 +17 336 . A <*> 0 . DP=12;I16=5,7,0,0,382,12810,0,0,658,37682,0,0,198,4060,0,0;QS=1,0;MQSB=0.760054;MQ0F=0 PL 0,36,255 +17 337 . C <*> 0 . DP=12;I16=5,7,0,0,443,16735,0,0,658,37682,0,0,200,4048,0,0;QS=1,0;MQSB=0.760054;MQ0F=0 PL 0,36,255 +17 338 . T <*> 0 . DP=12;I16=5,7,0,0,482,19532,0,0,658,37682,0,0,202,4052,0,0;QS=1,0;MQSB=0.760054;MQ0F=0 PL 0,36,255 +17 339 . C <*> 0 . DP=12;I16=5,7,0,0,459,17841,0,0,658,37682,0,0,204,4072,0,0;QS=1,0;MQSB=0.760054;MQ0F=0 PL 0,36,255 +17 340 . C <*> 0 . DP=12;I16=5,7,0,0,446,17110,0,0,658,37682,0,0,206,4108,0,0;QS=1,0;MQSB=0.760054;MQ0F=0 PL 0,36,255 +17 341 . T <*> 0 . DP=12;I16=5,7,0,0,499,20833,0,0,658,37682,0,0,208,4160,0,0;QS=1,0;MQSB=0.760054;MQ0F=0 PL 0,36,255 +17 342 . T <*> 0 . DP=12;I16=5,7,0,0,457,17601,0,0,658,37682,0,0,210,4228,0,0;QS=1,0;MQSB=0.760054;MQ0F=0 PL 0,36,255 +17 343 . G <*> 0 . DP=12;I16=5,7,0,0,460,17826,0,0,658,37682,0,0,212,4312,0,0;QS=1,0;MQSB=0.760054;MQ0F=0 PL 0,36,255 +17 344 . C <*> 0 . DP=12;I16=5,7,0,0,454,17546,0,0,658,37682,0,0,214,4412,0,0;QS=1,0;MQSB=0.760054;MQ0F=0 PL 0,36,255 +17 345 . T <*> 0 . DP=12;I16=5,7,0,0,472,18748,0,0,658,37682,0,0,216,4528,0,0;QS=1,0;MQSB=0.760054;MQ0F=0 PL 0,36,255 +17 346 . G <*> 0 . DP=12;I16=5,7,0,0,452,17412,0,0,658,37682,0,0,218,4660,0,0;QS=1,0;MQSB=0.760054;MQ0F=0 PL 0,36,255 +17 347 . G <*> 0 . DP=12;I16=5,7,0,0,454,17316,0,0,658,37682,0,0,220,4808,0,0;QS=1,0;MQSB=0.760054;MQ0F=0 PL 0,36,255 +17 348 . T <*> 0 . DP=12;I16=5,7,0,0,460,17876,0,0,658,37682,0,0,221,4921,0,0;QS=1,0;MQSB=0.760054;MQ0F=0 PL 0,36,255 +17 349 . T <*> 0 . DP=12;I16=5,7,0,0,473,18923,0,0,658,37682,0,0,222,5048,0,0;QS=1,0;MQSB=0.760054;MQ0F=0 PL 0,36,255 +17 350 . T <*> 0 . DP=11;I16=5,6,0,0,426,16634,0,0,629,36841,0,0,222,5086,0,0;QS=1,0;MQSB=0.891517;MQ0F=0 PL 0,33,255 +17 351 . G <*> 0 . DP=11;I16=5,6,0,0,430,16952,0,0,629,36841,0,0,222,5132,0,0;QS=1,0;MQSB=0.891517;MQ0F=0 PL 0,33,255 +17 352 . A <*> 0 . DP=11;I16=5,6,0,0,414,16100,0,0,629,36841,0,0,222,5186,0,0;QS=1,0;MQSB=0.891517;MQ0F=0 PL 0,33,255 +17 353 . G <*> 0 . DP=10;I16=5,5,0,0,386,15166,0,0,600,36000,0,0,222,5198,0,0;QS=1,0;MQSB=0.952347;MQ0F=0 PL 0,30,255 +17 354 . A <*> 0 . DP=10;I16=5,5,0,0,382,15130,0,0,600,36000,0,0,222,5218,0,0;QS=1,0;MQSB=0.952347;MQ0F=0 PL 0,30,255 +17 355 . G <*> 0 . DP=10;I16=5,5,0,0,374,14380,0,0,600,36000,0,0,222,5246,0,0;QS=1,0;MQSB=0.952347;MQ0F=0 PL 0,30,255 +17 356 . G <*> 0 . DP=10;I16=5,5,0,0,369,14149,0,0,600,36000,0,0,222,5282,0,0;QS=1,0;MQSB=0.952347;MQ0F=0 PL 0,30,255 +17 357 . C <*> 0 . DP=10;I16=4,5,0,0,336,12926,0,0,540,32400,0,0,196,4650,0,0;QS=1,0;MQSB=0.974597;MQ0F=0 PL 0,27,251 +17 358 . A <*> 0 . DP=10;I16=5,5,0,0,381,14901,0,0,600,36000,0,0,220,5274,0,0;QS=1,0;MQSB=0.952347;MQ0F=0 PL 0,30,255 +17 359 . G <*> 0 . DP=11;I16=5,6,0,0,420,16446,0,0,660,39600,0,0,219,5279,0,0;QS=1,0;MQSB=0.950952;MQ0F=0 PL 0,33,255 +17 360 . A <*> 0 . DP=11;I16=5,6,0,0,427,16793,0,0,660,39600,0,0,219,5291,0,0;QS=1,0;MQSB=0.950952;MQ0F=0 PL 0,33,255 +17 361 . A <*> 0 . DP=11;I16=5,6,0,0,427,16851,0,0,660,39600,0,0,218,5260,0,0;QS=1,0;MQSB=0.950952;MQ0F=0 PL 0,33,255 +17 362 . A <*> 0 . DP=10;I16=5,5,0,0,389,15439,0,0,600,36000,0,0,218,5234,0,0;QS=1,0;MQSB=0.952347;MQ0F=0 PL 0,30,255 +17 363 . A <*> 0 . DP=10;I16=5,5,0,0,382,14788,0,0,600,36000,0,0,218,5212,0,0;QS=1,0;MQSB=0.952347;MQ0F=0 PL 0,30,255 +17 364 . T <*> 0 . DP=10;I16=5,5,0,0,358,13294,0,0,600,36000,0,0,218,5194,0,0;QS=1,0;MQSB=0.952347;MQ0F=0 PL 0,30,255 +17 365 . G <*> 0 . DP=10;I16=5,5,0,0,391,15431,0,0,600,36000,0,0,218,5180,0,0;QS=1,0;MQSB=0.952347;MQ0F=0 PL 0,30,255 +17 366 . A <*> 0 . DP=10;I16=5,5,0,0,376,14352,0,0,600,36000,0,0,217,5121,0,0;QS=1,0;MQSB=0.952347;MQ0F=0 PL 0,30,255 +17 367 . T <*> 0 . DP=10;I16=5,5,0,0,368,13886,0,0,600,36000,0,0,216,5068,0,0;QS=1,0;MQSB=0.952347;MQ0F=0 PL 0,30,255 +17 368 . A <*> 0 . DP=10;I16=5,5,0,0,360,13632,0,0,600,36000,0,0,215,5021,0,0;QS=1,0;MQSB=0.952347;MQ0F=0 PL 0,30,255 +17 369 . T <*> 0 . DP=10;I16=5,5,0,0,386,15176,0,0,600,36000,0,0,214,4980,0,0;QS=1,0;MQSB=0.952347;MQ0F=0 PL 0,30,255 +17 370 . C <*> 0 . DP=10;I16=5,5,0,0,373,14349,0,0,600,36000,0,0,213,4945,0,0;QS=1,0;MQSB=0.952347;MQ0F=0 PL 0,30,255 +17 371 . T <*> 0 . DP=11;I16=5,6,0,0,435,17483,0,0,660,39600,0,0,212,4916,0,0;QS=1,0;MQSB=0.950952;MQ0F=0 PL 0,33,255 +17 372 . C <*> 0 . DP=11;I16=5,6,0,0,422,16450,0,0,660,39600,0,0,212,4894,0,0;QS=1,0;MQSB=0.950952;MQ0F=0 PL 0,33,255 +17 373 . A <*> 0 . DP=11;I16=5,6,0,0,416,16096,0,0,660,39600,0,0,211,4831,0,0;QS=1,0;MQSB=0.950952;MQ0F=0 PL 0,33,255 +17 374 . T <*> 0 . DP=11;I16=5,6,0,0,395,14795,0,0,660,39600,0,0,210,4778,0,0;QS=1,0;MQSB=0.950952;MQ0F=0 PL 0,33,255 +17 375 . A T,<*> 0 . DP=11;I16=5,5,0,1,399,15985,14,196,600,36000,60,3600,205,4719,4,16;QS=0.966102,0.0338983,0;SGB=-0.379885;RPB=1;MQB=1;MQSB=0.950952;BQB=1;MQ0F=0 PL 0,18,255,30,255,255 +17 376 . G <*> 0 . DP=11;I16=5,6,0,0,419,16089,0,0,660,39600,0,0,208,4702,0,0;QS=1,0;MQSB=0.950952;MQ0F=0 PL 0,33,255 +17 377 . T <*> 0 . DP=11;I16=5,6,0,0,414,16104,0,0,660,39600,0,0,207,4679,0,0;QS=1,0;MQSB=0.950952;MQ0F=0 PL 0,33,255 +17 378 . T <*> 0 . DP=10;I16=5,5,0,0,399,16003,0,0,600,36000,0,0,207,4665,0,0;QS=1,0;MQSB=0.952347;MQ0F=0 PL 0,30,255 +17 379 . G <*> 0 . DP=10;I16=5,5,0,0,385,14907,0,0,600,36000,0,0,207,4659,0,0;QS=1,0;MQSB=0.952347;MQ0F=0 PL 0,30,255 +17 380 . C <*> 0 . DP=10;I16=5,5,0,0,391,15345,0,0,600,36000,0,0,206,4612,0,0;QS=1,0;MQSB=0.952347;MQ0F=0 PL 0,30,255 +17 381 . T <*> 0 . DP=10;I16=5,5,0,0,415,17335,0,0,600,36000,0,0,205,4575,0,0;QS=1,0;MQSB=0.952347;MQ0F=0 PL 0,30,255 +17 382 . T <*> 0 . DP=10;I16=5,5,0,0,401,16215,0,0,600,36000,0,0,204,4548,0,0;QS=1,0;MQSB=0.952347;MQ0F=0 PL 0,30,255 +17 383 . T <*> 0 . DP=10;I16=5,5,0,0,394,15584,0,0,600,36000,0,0,203,4531,0,0;QS=1,0;MQSB=0.952347;MQ0F=0 PL 0,30,255 +17 384 . A <*> 0 . DP=10;I16=5,5,0,0,370,14282,0,0,600,36000,0,0,202,4524,0,0;QS=1,0;MQSB=0.952347;MQ0F=0 PL 0,30,255 +17 385 . C <*> 0 . DP=10;I16=5,5,0,0,358,13180,0,0,600,36000,0,0,200,4476,0,0;QS=1,0;MQSB=0.952347;MQ0F=0 PL 0,30,255 +17 386 . T <*> 0 . DP=10;I16=5,5,0,0,402,16458,0,0,600,36000,0,0,198,4436,0,0;QS=1,0;MQSB=0.952347;MQ0F=0 PL 0,30,255 +17 387 . T <*> 0 . DP=10;I16=5,5,0,0,397,15951,0,0,600,36000,0,0,196,4404,0,0;QS=1,0;MQSB=0.952347;MQ0F=0 PL 0,30,255 +17 388 . T <*> 0 . DP=10;I16=5,5,0,0,394,15676,0,0,600,36000,0,0,194,4380,0,0;QS=1,0;MQSB=0.952347;MQ0F=0 PL 0,30,255 +17 389 . G <*> 0 . DP=10;I16=5,5,0,0,384,14858,0,0,600,36000,0,0,192,4364,0,0;QS=1,0;MQSB=0.952347;MQ0F=0 PL 0,30,255 +17 390 . C <*> 0 . DP=10;I16=5,5,0,0,377,14407,0,0,600,36000,0,0,190,4356,0,0;QS=1,0;MQSB=0.952347;MQ0F=0 PL 0,30,255 +17 391 . A <*> 0 . DP=10;I16=6,4,0,0,392,15500,0,0,569,33241,0,0,189,4355,0,0;QS=1,0;MQSB=0.895781;MQ0F=0 PL 0,30,255 +17 392 . T <*> 0 . DP=11;I16=7,4,0,0,398,14994,0,0,629,36841,0,0,189,4361,0,0;QS=1,0;MQSB=0.924449;MQ0F=0 PL 0,33,255 +17 393 . A <*> 0 . DP=11;I16=7,4,0,0,413,15853,0,0,629,36841,0,0,190,4376,0,0;QS=1,0;MQSB=0.924449;MQ0F=0 PL 0,33,255 +17 394 . T <*> 0 . DP=11;I16=7,4,0,0,424,16506,0,0,629,36841,0,0,191,4401,0,0;QS=1,0;MQSB=0.924449;MQ0F=0 PL 0,33,255 +17 395 . T <*> 0 . DP=11;I16=7,4,0,0,433,17273,0,0,629,36841,0,0,192,4436,0,0;QS=1,0;MQSB=0.924449;MQ0F=0 PL 0,33,255 +17 396 . T <*> 0 . DP=11;I16=7,4,0,0,436,17446,0,0,629,36841,0,0,193,4481,0,0;QS=1,0;MQSB=0.924449;MQ0F=0 PL 0,33,255 +17 397 . T <*> 0 . DP=11;I16=7,4,0,0,429,16877,0,0,629,36841,0,0,193,4485,0,0;QS=1,0;MQSB=0.924449;MQ0F=0 PL 0,33,255 +17 398 . A <*> 0 . DP=10;I16=6,4,0,0,397,15817,0,0,569,33241,0,0,193,4447,0,0;QS=1,0;MQSB=0.895781;MQ0F=0 PL 0,30,255 +17 399 . A <*> 0 . DP=10;I16=6,4,0,0,400,16172,0,0,569,33241,0,0,193,4417,0,0;QS=1,0;MQSB=0.895781;MQ0F=0 PL 0,30,255 +17 400 . A <*> 0 . DP=11;I16=6,5,0,0,419,16363,0,0,629,36841,0,0,191,4297,0,0;QS=1,0;MQSB=0.8618;MQ0F=0 PL 0,33,255 +17 401 . A <*> 0 . DP=11;I16=6,4,0,0,391,15483,0,0,569,33241,0,0,165,3565,0,0;QS=1,0;MQSB=0.895781;MQ0F=0 PL 0,30,255 +17 402 . T <*> 0 . DP=11;I16=6,5,0,0,421,16453,0,0,629,36841,0,0,189,4097,0,0;QS=1,0;MQSB=0.8618;MQ0F=0 PL 0,33,255 +17 403 . T <*> 0 . DP=11;I16=6,5,0,0,426,16580,0,0,629,36841,0,0,188,4018,0,0;QS=1,0;MQSB=0.8618;MQ0F=0 PL 0,33,255 +17 404 . G <*> 0 . DP=11;I16=6,5,0,0,421,16197,0,0,629,36841,0,0,187,3953,0,0;QS=1,0;MQSB=0.8618;MQ0F=0 PL 0,33,255 +17 405 . T <*> 0 . DP=10;I16=6,4,0,0,387,15059,0,0,569,33241,0,0,187,3901,0,0;QS=1,0;MQSB=0.895781;MQ0F=0 PL 0,30,255 +17 406 . G <*> 0 . DP=10;I16=6,4,0,0,340,12376,0,0,569,33241,0,0,187,3861,0,0;QS=1,0;MQSB=0.895781;MQ0F=0 PL 0,30,247 +17 407 . A <*> 0 . DP=10;I16=6,4,0,0,380,14678,0,0,569,33241,0,0,186,3784,0,0;QS=1,0;MQSB=0.895781;MQ0F=0 PL 0,30,255 +17 408 . C <*> 0 . DP=10;I16=6,4,0,0,343,12191,0,0,569,33241,0,0,185,3721,0,0;QS=1,0;MQSB=0.895781;MQ0F=0 PL 0,30,244 +17 409 . T <*> 0 . DP=11;I16=7,4,0,0,400,15038,0,0,629,36841,0,0,184,3672,0,0;QS=1,0;MQSB=0.924449;MQ0F=0 PL 0,33,255 +17 410 . T <*> 0 . DP=11;I16=7,4,0,0,415,16051,0,0,629,36841,0,0,184,3638,0,0;QS=1,0;MQSB=0.924449;MQ0F=0 PL 0,33,255 +17 411 . T <*> 0 . DP=11;I16=7,3,0,0,404,16388,0,0,569,33241,0,0,158,2946,0,0;QS=1,0;MQSB=0.916482;MQ0F=0 PL 0,30,255 +17 412 . C <*> 0 . DP=11;I16=7,4,0,0,413,16037,0,0,629,36841,0,0,182,3522,0,0;QS=1,0;MQSB=0.924449;MQ0F=0 PL 0,33,255 +17 413 . A <*> 0 . DP=11;I16=7,4,0,0,443,17907,0,0,629,36841,0,0,181,3491,0,0;QS=1,0;MQSB=0.924449;MQ0F=0 PL 0,33,255 +17 414 . T <*> 0 . DP=11;I16=7,4,0,0,425,16499,0,0,629,36841,0,0,180,3478,0,0;QS=1,0;MQSB=0.924449;MQ0F=0 PL 0,33,255 +17 415 . G <*> 0 . DP=11;I16=7,4,0,0,397,14511,0,0,629,36841,0,0,179,3483,0,0;QS=1,0;MQSB=0.924449;MQ0F=0 PL 0,33,255 +17 416 . G <*> 0 . DP=11;I16=6,4,0,0,365,13451,0,0,569,33241,0,0,163,3281,0,0;QS=1,0;MQSB=0.895781;MQ0F=0 PL 0,30,253 +17 417 . C <*> 0 . DP=11;I16=7,4,0,0,394,14514,0,0,629,36841,0,0,176,3496,0,0;QS=1,0;MQSB=0.924449;MQ0F=0 PL 0,33,255 +17 418 . A <*> 0 . DP=11;I16=7,4,0,0,412,15720,0,0,629,36841,0,0,173,3451,0,0;QS=1,0;MQSB=0.924449;MQ0F=0 PL 0,33,255 +17 419 . T <*> 0 . DP=11;I16=7,4,0,0,394,14726,0,0,629,36841,0,0,170,3420,0,0;QS=1,0;MQSB=0.924449;MQ0F=0 PL 0,33,255 +17 420 . A <*> 0 . DP=12;I16=7,5,0,0,423,15455,0,0,689,40441,0,0,167,3403,0,0;QS=1,0;MQSB=0.896474;MQ0F=0 PL 0,36,255 +17 421 . A <*> 0 . DP=14;I16=8,6,0,0,508,18992,0,0,778,44882,0,0,165,3401,0,0;QS=1,0;MQSB=0.740818;MQ0F=0 PL 0,42,255 +17 422 . A <*> 0 . DP=14;I16=8,5,0,0,472,17788,0,0,718,41282,0,0,140,2792,0,0;QS=1,0;MQSB=0.765017;MQ0F=0 PL 0,39,255 +17 423 . T <*> 0 . DP=13;I16=8,5,0,0,485,18253,0,0,718,41282,0,0,166,3452,0,0;QS=1,0;MQSB=0.765017;MQ0F=0 PL 0,39,255 +17 424 . A <*> 0 . DP=13;I16=8,5,0,0,455,16265,0,0,718,41282,0,0,167,3505,0,0;QS=1,0;MQSB=0.765017;MQ0F=0 PL 0,39,255 +17 425 . A <*> 0 . DP=11;I16=6,5,0,0,381,13925,0,0,598,34082,0,0,170,3574,0,0;QS=1,0;MQSB=0.683497;MQ0F=0 PL 0,33,249 +17 426 . T <*> 0 . DP=11;I16=6,4,0,0,315,10583,0,0,538,30482,0,0,147,2981,0,0;QS=1,0;MQSB=0.727822;MQ0F=0 PL 0,30,225 +17 427 . A <*> 0 . DP=11;I16=6,5,0,0,358,12202,0,0,598,34082,0,0,174,3650,0,0;QS=1,0;MQSB=0.683497;MQ0F=0 PL 0,33,242 +17 428 . C <*> 0 . DP=11;I16=6,5,0,0,370,12672,0,0,598,34082,0,0,176,3706,0,0;QS=1,0;MQSB=0.683497;MQ0F=0 PL 0,33,254 +17 429 . T <*> 0 . DP=11;I16=6,5,0,0,401,15207,0,0,598,34082,0,0,178,3774,0,0;QS=1,0;MQSB=0.683497;MQ0F=0 PL 0,33,255 +17 430 . G <*> 0 . DP=11;I16=6,5,0,0,364,12556,0,0,598,34082,0,0,180,3854,0,0;QS=1,0;MQSB=0.683497;MQ0F=0 PL 0,33,246 +17 431 . G <*> 0 . DP=11;I16=5,5,0,0,317,10453,0,0,538,30482,0,0,182,3946,0,0;QS=1,0;MQSB=0.523791;MQ0F=0 PL 0,30,225 +17 432 . T <*> 0 . DP=10;I16=5,5,0,0,364,13442,0,0,538,30482,0,0,185,4049,0,0;QS=1,0;MQSB=0.523791;MQ0F=0 PL 0,30,255 +17 433 . T <*> 0 . DP=10;I16=5,4,0,0,314,11296,0,0,478,26882,0,0,163,3537,0,0;QS=1,0;MQSB=0.649731;MQ0F=0 PL 0,27,227 +17 434 . T <*> 0 . DP=10;I16=5,5,0,0,339,11787,0,0,538,30482,0,0,191,4285,0,0;QS=1,0;MQSB=0.523791;MQ0F=0 PL 0,30,243 +17 435 . A <*> 0 . DP=10;I16=5,5,0,0,346,12322,0,0,538,30482,0,0,192,4318,0,0;QS=1,0;MQSB=0.523791;MQ0F=0 PL 0,30,237 +17 436 . T <*> 0 . DP=9;I16=4,5,0,0,305,10551,0,0,478,26882,0,0,194,4360,0,0;QS=1,0;MQSB=0.487298;MQ0F=0 PL 0,27,223 +17 437 . T <*> 0 . DP=9;I16=3,5,0,0,271,9505,0,0,449,26041,0,0,180,4154,0,0;QS=1,0;MQSB=0.750668;MQ0F=0 PL 0,24,207 +17 438 . A <*> 0 . DP=9;I16=4,4,0,0,286,10426,0,0,418,23282,0,0,173,3843,0,0;QS=1,0;MQSB=0.62023;MQ0F=0 PL 0,24,216 +17 439 . C <*> 0 . DP=9;I16=4,5,0,0,311,10989,0,0,478,26882,0,0,200,4534,0,0;QS=1,0;MQSB=0.487298;MQ0F=0 PL 0,27,224 +17 440 . A <*> 0 . DP=9;I16=4,5,0,0,346,13482,0,0,478,26882,0,0,202,4608,0,0;QS=1,0;MQSB=0.487298;MQ0F=0 PL 0,27,247 +17 441 . G <*> 0 . DP=9;I16=4,5,0,0,278,8848,0,0,478,26882,0,0,204,4690,0,0;QS=1,0;MQSB=0.487298;MQ0F=0 PL 0,27,198 +17 442 . A <*> 0 . DP=9;I16=4,5,0,0,335,12765,0,0,478,26882,0,0,206,4780,0,0;QS=1,0;MQSB=0.487298;MQ0F=0 PL 0,27,233 +17 443 . A <*> 0 . DP=9;I16=4,5,0,0,353,13985,0,0,478,26882,0,0,208,4878,0,0;QS=1,0;MQSB=0.487298;MQ0F=0 PL 0,27,246 +17 444 . G <*> 0 . DP=9;I16=4,5,0,0,314,11134,0,0,478,26882,0,0,210,4984,0,0;QS=1,0;MQSB=0.487298;MQ0F=0 PL 0,27,227 +17 445 . C <*> 0 . DP=9;I16=4,5,0,0,311,10911,0,0,478,26882,0,0,212,5098,0,0;QS=1,0;MQSB=0.487298;MQ0F=0 PL 0,27,219 +17 446 . A <*> 0 . DP=9;I16=4,5,0,0,326,12046,0,0,478,26882,0,0,213,5169,0,0;QS=1,0;MQSB=0.487298;MQ0F=0 PL 0,27,232 +17 447 . C <*> 0 . DP=9;I16=4,5,0,0,329,12167,0,0,478,26882,0,0,211,5095,0,0;QS=1,0;MQSB=0.487298;MQ0F=0 PL 0,27,235 +17 448 . T <*> 0 . DP=9;I16=4,5,0,0,345,13353,0,0,478,26882,0,0,209,5025,0,0;QS=1,0;MQSB=0.487298;MQ0F=0 PL 0,27,240 +17 449 . A <*> 0 . DP=9;I16=4,5,0,0,351,13765,0,0,478,26882,0,0,207,4959,0,0;QS=1,0;MQSB=0.487298;MQ0F=0 PL 0,27,245 +17 450 . G <*> 0 . DP=9;I16=4,5,0,0,318,11826,0,0,478,26882,0,0,205,4897,0,0;QS=1,0;MQSB=0.487298;MQ0F=0 PL 0,27,233 +17 451 . A <*> 0 . DP=9;I16=4,5,0,0,339,13205,0,0,478,26882,0,0,203,4839,0,0;QS=1,0;MQSB=0.487298;MQ0F=0 PL 0,27,244 +17 452 . A <*> 0 . DP=9;I16=4,4,0,0,311,12443,0,0,418,23282,0,0,182,4424,0,0;QS=1,0;MQSB=0.62023;MQ0F=0 PL 0,24,225 +17 453 . A <*> 0 . DP=9;I16=3,4,0,0,282,11452,0,0,389,22441,0,0,156,3786,0,0;QS=1,0;MQSB=0.810265;MQ0F=0 PL 0,21,221 +17 454 . A <*> 0 . DP=10;I16=5,5,0,0,370,14072,0,0,538,30482,0,0,197,4689,0,0;QS=1,0;MQSB=0.523791;MQ0F=0 PL 0,30,255 +17 455 . T <*> 0 . DP=11;I16=5,6,0,0,386,13872,0,0,575,31851,0,0,196,4648,0,0;QS=1,0;MQSB=0.683497;MQ0F=0 PL 0,33,255 +17 456 . G <*> 0 . DP=11;I16=4,6,0,0,353,12645,0,0,546,31010,0,0,171,3989,0,0;QS=1,0;MQSB=0.895781;MQ0F=0 PL 0,30,245 +17 457 . C <*> 0 . DP=11;I16=5,6,0,0,382,13622,0,0,575,31851,0,0,196,4588,0,0;QS=1,0;MQSB=0.683497;MQ0F=0 PL 0,33,255 +17 458 . A <*> 0 . DP=11;I16=5,6,0,0,404,15008,0,0,575,31851,0,0,196,4570,0,0;QS=1,0;MQSB=0.683497;MQ0F=0 PL 0,33,255 +17 459 . T <*> 0 . DP=11;I16=5,6,0,0,380,13694,0,0,575,31851,0,0,196,4560,0,0;QS=1,0;MQSB=0.683497;MQ0F=0 PL 0,33,255 +17 460 . G <*> 0 . DP=10;I16=5,5,0,0,366,13542,0,0,515,28251,0,0,197,4557,0,0;QS=1,0;MQSB=0.761877;MQ0F=0 PL 0,30,255 +17 461 . T <*> 0 . DP=10;I16=5,5,0,0,382,15028,0,0,515,28251,0,0,198,4560,0,0;QS=1,0;MQSB=0.761877;MQ0F=0 PL 0,30,255 +17 462 . G <*> 0 . DP=10;I16=5,5,0,0,350,12490,0,0,515,28251,0,0,199,4569,0,0;QS=1,0;MQSB=0.761877;MQ0F=0 PL 0,30,241 +17 463 . G <*> 0 . DP=10;I16=5,5,0,0,310,10258,0,0,515,28251,0,0,200,4584,0,0;QS=1,0;MQSB=0.761877;MQ0F=0 PL 0,30,221 +17 464 . A <*> 0 . DP=10;I16=4,4,0,0,287,10449,0,0,426,23810,0,0,169,3931,0,0;QS=1,0;MQSB=0.868321;MQ0F=0 PL 0,24,213 +17 465 . C <*> 0 . DP=10;I16=5,4,0,0,326,11950,0,0,455,24651,0,0,196,4596,0,0;QS=1,0;MQSB=0.730948;MQ0F=0 PL 0,27,231 +17 466 . A <*> 0 . DP=10;I16=5,5,0,0,379,14569,0,0,515,28251,0,0,203,4665,0,0;QS=1,0;MQSB=0.761877;MQ0F=0 PL 0,30,255 +17 467 . A <*> 0 . DP=10;I16=5,4,0,0,356,14182,0,0,455,24651,0,0,199,4639,0,0;QS=1,0;MQSB=0.730948;MQ0F=0 PL 0,27,248 +17 468 . A <*> 0 . DP=10;I16=5,5,0,0,357,13375,0,0,515,28251,0,0,202,4604,0,0;QS=1,0;MQSB=0.761877;MQ0F=0 PL 0,30,251 +17 469 . A <*> 0 . DP=10;I16=5,5,0,0,387,15581,0,0,515,28251,0,0,201,4563,0,0;QS=1,0;MQSB=0.761877;MQ0F=0 PL 0,30,255 +17 470 . G <*> 0 . DP=10;I16=5,5,0,0,328,11334,0,0,515,28251,0,0,200,4532,0,0;QS=1,0;MQSB=0.761877;MQ0F=0 PL 0,30,238 +17 471 . T <*> 0 . DP=11;I16=5,4,0,0,319,11637,0,0,478,26882,0,0,183,4255,0,0;QS=1,0;MQSB=0.649731;MQ0F=0 PL 0,27,232 +17 472 . T <*> 0 . DP=10;I16=4,5,0,0,337,12787,0,0,486,27410,0,0,175,3875,0,0;QS=1,0;MQSB=0.89338;MQ0F=0 PL 0,27,237 +17 473 . G <*> 0 . DP=10;I16=4,5,0,0,355,14039,0,0,486,27410,0,0,176,3874,0,0;QS=1,0;MQSB=0.89338;MQ0F=0 PL 0,27,249 +17 474 . G <*> 0 . DP=11;I16=5,5,0,0,363,13461,0,0,546,31010,0,0,177,3883,0,0;QS=1,0;MQSB=0.952347;MQ0F=0 PL 0,30,255 +17 475 . G <*> 0 . DP=11;I16=6,5,0,0,376,13342,0,0,575,31851,0,0,204,4528,0,0;QS=1,0;MQSB=0.8618;MQ0F=0 PL 0,33,252 +17 476 . A <*> 0 . DP=11;I16=6,5,0,0,404,15370,0,0,575,31851,0,0,205,4511,0,0;QS=1,0;MQSB=0.8618;MQ0F=0 PL 0,33,255 +17 477 . T <*> 0 . DP=11;I16=6,5,0,0,413,15979,0,0,575,31851,0,0,206,4508,0,0;QS=1,0;MQSB=0.8618;MQ0F=0 PL 0,33,255 +17 478 . T <*> 0 . DP=11;I16=6,5,0,0,414,15806,0,0,575,31851,0,0,207,4519,0,0;QS=1,0;MQSB=0.8618;MQ0F=0 PL 0,33,255 +17 479 . A <*> 0 . DP=11;I16=6,5,0,0,441,17977,0,0,575,31851,0,0,208,4544,0,0;QS=1,0;MQSB=0.8618;MQ0F=0 PL 0,33,255 +17 480 . G <*> 0 . DP=11;I16=6,5,0,0,421,16261,0,0,575,31851,0,0,208,4532,0,0;QS=1,0;MQSB=0.8618;MQ0F=0 PL 0,33,255 +17 481 . G <*> 0 . DP=11;I16=6,5,0,0,416,16016,0,0,575,31851,0,0,207,4481,0,0;QS=1,0;MQSB=0.8618;MQ0F=0 PL 0,33,255 +17 482 . A <*> 0 . DP=11;I16=6,5,0,0,434,17374,0,0,575,31851,0,0,206,4440,0,0;QS=1,0;MQSB=0.8618;MQ0F=0 PL 0,33,255 +17 483 . G <*> 0 . DP=11;I16=6,5,0,0,426,16626,0,0,575,31851,0,0,205,4409,0,0;QS=1,0;MQSB=0.8618;MQ0F=0 PL 0,33,255 +17 484 . A <*> 0 . DP=11;I16=6,5,0,0,451,18653,0,0,575,31851,0,0,204,4388,0,0;QS=1,0;MQSB=0.8618;MQ0F=0 PL 0,33,255 +17 485 . G <*> 0 . DP=11;I16=6,5,0,0,419,16073,0,0,575,31851,0,0,202,4328,0,0;QS=1,0;MQSB=0.8618;MQ0F=0 PL 0,33,255 +17 486 . A <*> 0 . DP=11;I16=6,5,0,0,452,18618,0,0,575,31851,0,0,200,4280,0,0;QS=1,0;MQSB=0.8618;MQ0F=0 PL 0,33,255 +17 487 . G <*> 0 . DP=11;I16=6,5,0,0,411,15483,0,0,575,31851,0,0,198,4244,0,0;QS=1,0;MQSB=0.8618;MQ0F=0 PL 0,33,255 +17 488 . A <*> 0 . DP=11;I16=5,5,0,0,388,15102,0,0,546,31010,0,0,171,3595,0,0;QS=1,0;MQSB=0.952347;MQ0F=0 PL 0,30,255 +17 489 . A <*> 0 . DP=11;I16=6,5,0,0,393,14565,0,0,575,31851,0,0,194,4208,0,0;QS=1,0;MQSB=0.8618;MQ0F=0 PL 0,33,255 +17 490 . A <*> 0 . DP=11;I16=6,5,0,0,401,14927,0,0,575,31851,0,0,192,4208,0,0;QS=1,0;MQSB=0.8618;MQ0F=0 PL 0,33,255 +17 491 . T <*> 0 . DP=11;I16=6,5,0,0,385,13773,0,0,575,31851,0,0,190,4220,0,0;QS=1,0;MQSB=0.8618;MQ0F=0 PL 0,33,255 +17 492 . G <*> 0 . DP=10;I16=5,5,0,0,367,13741,0,0,546,31010,0,0,189,4243,0,0;QS=1,0;MQSB=0.952347;MQ0F=0 PL 0,30,251 +17 493 . A <*> 0 . DP=9;I16=4,4,0,0,330,13624,0,0,426,23810,0,0,167,3791,0,0;QS=1,0;MQSB=0.868321;MQ0F=0 PL 0,24,240 +17 494 . A <*> 0 . DP=9;I16=4,5,0,0,371,15531,0,0,486,27410,0,0,189,4315,0,0;QS=1,0;MQSB=0.89338;MQ0F=0 PL 0,27,255 +17 495 . G <*> 0 . DP=9;I16=4,5,0,0,336,12694,0,0,486,27410,0,0,189,4363,0,0;QS=1,0;MQSB=0.89338;MQ0F=0 PL 0,27,244 +17 496 . A <*> 0 . DP=9;I16=4,5,0,0,348,13636,0,0,486,27410,0,0,188,4370,0,0;QS=1,0;MQSB=0.89338;MQ0F=0 PL 0,27,249 +17 497 . C <*> 0 . DP=9;I16=4,5,0,0,334,12616,0,0,486,27410,0,0,184,4238,0,0;QS=1,0;MQSB=0.89338;MQ0F=0 PL 0,27,239 +17 498 . A <*> 0 . DP=9;I16=4,5,0,0,362,14588,0,0,486,27410,0,0,180,4118,0,0;QS=1,0;MQSB=0.89338;MQ0F=0 PL 0,27,252 +17 499 . T <*> 0 . DP=10;I16=5,5,0,0,370,13844,0,0,546,31010,0,0,176,4010,0,0;QS=1,0;MQSB=0.952347;MQ0F=0 PL 0,30,255 +17 500 . A <*> 0 . DP=10;I16=5,5,0,0,379,14465,0,0,546,31010,0,0,172,3864,0,0;QS=1,0;MQSB=0.952347;MQ0F=0 PL 0,30,255 +17 501 . T <*> 0 . DP=9;I16=5,4,0,0,345,13407,0,0,486,27410,0,0,169,3729,0,0;QS=1,0;MQSB=0.974597;MQ0F=0 PL 0,27,241 +17 502 . G <*> 0 . DP=9;I16=5,4,0,0,317,11369,0,0,486,27410,0,0,166,3604,0,0;QS=1,0;MQSB=0.974597;MQ0F=0 PL 0,27,235 +17 503 . T <*> 0 . DP=9;I16=5,4,0,0,311,11263,0,0,486,27410,0,0,163,3489,0,0;QS=1,0;MQSB=0.974597;MQ0F=0 PL 0,27,234 +17 504 . C <*> 0 . DP=9;I16=5,4,0,0,295,9993,0,0,486,27410,0,0,160,3384,0,0;QS=1,0;MQSB=0.974597;MQ0F=0 PL 0,27,219 +17 505 . C <*> 0 . DP=9;I16=5,4,0,0,299,10467,0,0,486,27410,0,0,157,3289,0,0;QS=1,0;MQSB=0.974597;MQ0F=0 PL 0,27,221 +17 506 . A <*> 0 . DP=9;I16=5,4,0,0,310,10972,0,0,486,27410,0,0,154,3204,0,0;QS=1,0;MQSB=0.974597;MQ0F=0 PL 0,27,231 +17 507 . C <*> 0 . DP=9;I16=5,4,0,0,311,10937,0,0,486,27410,0,0,151,3129,0,0;QS=1,0;MQSB=0.974597;MQ0F=0 PL 0,27,226 +17 508 . A <*> 0 . DP=9;I16=5,4,0,0,306,11130,0,0,486,27410,0,0,148,3064,0,0;QS=1,0;MQSB=0.974597;MQ0F=0 PL 0,27,220 +17 509 . C <*> 0 . DP=9;I16=5,4,0,0,339,12893,0,0,486,27410,0,0,145,3009,0,0;QS=1,0;MQSB=0.974597;MQ0F=0 PL 0,27,241 +17 510 . A <*> 0 . DP=8;I16=4,4,0,0,292,10906,0,0,426,23810,0,0,143,2963,0,0;QS=1,0;MQSB=0.868321;MQ0F=0 PL 0,24,221 +17 511 . A <*> 0 . DP=8;I16=4,4,0,0,311,12335,0,0,426,23810,0,0,141,2925,0,0;QS=1,0;MQSB=0.868321;MQ0F=0 PL 0,24,233 +17 512 . A <*> 0 . DP=8;I16=4,4,0,0,309,12187,0,0,426,23810,0,0,139,2895,0,0;QS=1,0;MQSB=0.868321;MQ0F=0 PL 0,24,231 +17 513 . A <*> 0 . DP=8;I16=4,4,0,0,310,12250,0,0,426,23810,0,0,137,2873,0,0;QS=1,0;MQSB=0.868321;MQ0F=0 PL 0,24,233 +17 514 . A <*> 0 . DP=8;I16=4,4,0,0,313,12385,0,0,426,23810,0,0,135,2859,0,0;QS=1,0;MQSB=0.868321;MQ0F=0 PL 0,24,235 +17 515 . C <*> 0 . DP=8;I16=4,4,0,0,272,9636,0,0,426,23810,0,0,133,2853,0,0;QS=1,0;MQSB=0.868321;MQ0F=0 PL 0,24,211 +17 516 . C <*> 0 . DP=8;I16=4,4,0,0,280,10438,0,0,426,23810,0,0,131,2855,0,0;QS=1,0;MQSB=0.868321;MQ0F=0 PL 0,24,215 +17 517 . T <*> 0 . DP=8;I16=4,4,0,0,330,13694,0,0,426,23810,0,0,129,2865,0,0;QS=1,0;MQSB=0.868321;MQ0F=0 PL 0,24,242 +17 518 . G <*> 0 . DP=8;I16=4,4,0,0,289,10617,0,0,426,23810,0,0,127,2883,0,0;QS=1,0;MQSB=0.868321;MQ0F=0 PL 0,24,220 +17 519 . T <*> 0 . DP=8;I16=4,4,0,0,305,11719,0,0,426,23810,0,0,125,2909,0,0;QS=1,0;MQSB=0.868321;MQ0F=0 PL 0,24,224 +17 520 . T <*> 0 . DP=8;I16=4,4,0,0,298,11414,0,0,426,23810,0,0,123,2943,0,0;QS=1,0;MQSB=0.868321;MQ0F=0 PL 0,24,223 +17 521 . C <*> 0 . DP=7;I16=4,3,0,0,270,10846,0,0,366,20210,0,0,122,2984,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,204 +17 522 . A <*> 0 . DP=5;I16=3,2,0,0,200,8046,0,0,277,15769,0,0,123,3029,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,15,170 +17 523 . T <*> 0 . DP=5;I16=3,2,0,0,202,8354,0,0,277,15769,0,0,124,3076,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,15,166 +17 524 . T <*> 0 . DP=5;I16=3,1,0,0,160,6434,0,0,217,12169,0,0,100,2500,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,140 +17 525 . G <*> 0 . DP=5;I16=3,1,0,0,148,5702,0,0,217,12169,0,0,100,2500,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,129 +17 526 . C <*> 0 . DP=5;I16=3,1,0,0,151,6033,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,131 +17 527 . A <*> 0 . DP=6;I16=4,2,0,0,220,8220,0,0,337,19369,0,0,125,3125,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,18,181 +17 528 . G <*> 0 . DP=6;I16=4,2,0,0,236,9362,0,0,337,19369,0,0,126,3126,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,18,193 +17 529 . C <*> 0 . DP=6;I16=4,2,0,0,231,9215,0,0,337,19369,0,0,127,3129,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,18,184 +17 530 . T <*> 0 . DP=6;I16=4,2,0,0,252,10690,0,0,337,19369,0,0,127,3085,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,18,202 +17 531 . T <*> 0 . DP=6;I16=4,2,0,0,239,9609,0,0,337,19369,0,0,126,2996,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,18,193 +17 532 . T <*> 0 . DP=6;I16=4,2,0,0,234,9212,0,0,337,19369,0,0,125,2913,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,18,192 +17 533 . C <*> 0 . DP=6;I16=4,2,0,0,220,8368,0,0,337,19369,0,0,124,2836,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,18,180 +17 534 . T <*> 0 . DP=6;I16=4,2,0,0,255,10895,0,0,337,19369,0,0,123,2765,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,18,205 +17 535 . A <*> 0 . DP=6;I16=4,2,0,0,231,8961,0,0,337,19369,0,0,122,2700,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,18,189 +17 536 . C <*> 0 . DP=6;I16=4,2,0,0,195,7075,0,0,337,19369,0,0,121,2641,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,18,157 +17 537 . C <*> 0 . DP=6;I16=4,2,0,0,222,8546,0,0,337,19369,0,0,120,2588,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,18,183 +17 538 . A <*> 0 . DP=6;I16=4,2,0,0,222,8490,0,0,337,19369,0,0,119,2541,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,18,181 +17 539 . T <*> 0 . DP=6;I16=4,2,0,0,222,8412,0,0,337,19369,0,0,118,2500,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,18,181 +17 540 . C <*> 0 . DP=6;I16=4,2,0,0,218,8258,0,0,337,19369,0,0,117,2465,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,18,178 +17 541 . A <*> 0 . DP=6;I16=4,1,0,0,187,7293,0,0,277,15769,0,0,91,1811,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,150 +17 542 . C <*> 0 . DP=6;I16=4,2,0,0,212,7902,0,0,337,19369,0,0,115,2413,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,18,174 +17 543 . C <*> 0 . DP=6;I16=4,2,0,0,230,9164,0,0,337,19369,0,0,114,2396,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,18,188 +17 544 . A <*> 0 . DP=6;I16=4,2,0,0,223,8733,0,0,337,19369,0,0,113,2385,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,18,180 +17 545 . A <*> 0 . DP=6;I16=4,2,0,0,230,9494,0,0,337,19369,0,0,112,2380,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,18,184 +17 546 . A <*> 0 . DP=6;I16=4,2,0,0,236,9540,0,0,337,19369,0,0,111,2381,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,18,193 +17 547 . A <*> 0 . DP=6;I16=4,2,0,0,240,9712,0,0,337,19369,0,0,109,2339,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,18,195 +17 548 . A <*> 0 . DP=7;I16=4,3,0,0,261,10277,0,0,397,22969,0,0,107,2305,0,0;QS=1,0;MQSB=0.810265;MQ0F=0 PL 0,21,211 +17 549 . T <*> 0 . DP=7;I16=4,3,0,0,266,10342,0,0,397,22969,0,0,106,2280,0,0;QS=1,0;MQSB=0.810265;MQ0F=0 PL 0,21,208 +17 550 . T <*> 0 . DP=7;I16=4,3,0,0,275,10863,0,0,397,22969,0,0,104,2216,0,0;QS=1,0;MQSB=0.810265;MQ0F=0 PL 0,21,220 +17 551 . G <*> 0 . DP=7;I16=4,3,0,0,259,9883,0,0,397,22969,0,0,102,2164,0,0;QS=1,0;MQSB=0.810265;MQ0F=0 PL 0,21,208 +17 552 . C <*> 0 . DP=7;I16=4,3,0,0,260,10162,0,0,397,22969,0,0,100,2124,0,0;QS=1,0;MQSB=0.810265;MQ0F=0 PL 0,21,208 +17 553 . A <*> 0 . DP=8;I16=5,2,0,0,249,9067,0,0,397,22969,0,0,79,1721,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,21,194 +17 554 . A <*> 0 . DP=8;I16=5,3,0,0,273,9901,0,0,457,26569,0,0,95,1977,0,0;QS=1,0;MQSB=0.750668;MQ0F=0 PL 0,24,211 +17 555 . A <*> 0 . DP=7;I16=4,3,0,0,262,10108,0,0,397,22969,0,0,94,1920,0,0;QS=1,0;MQSB=0.810265;MQ0F=0 PL 0,21,211 +17 556 . C <*> 0 . DP=6;I16=4,2,0,0,227,8701,0,0,360,21600,0,0,94,1872,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,186 +17 557 . A <*> 0 . DP=6;I16=4,2,0,0,226,8674,0,0,360,21600,0,0,94,1832,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,186 +17 558 . A <*> 0 . DP=6;I16=4,2,0,0,215,8343,0,0,360,21600,0,0,94,1800,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,177 +17 559 . C <*> 0 . DP=6;I16=4,2,0,0,204,7318,0,0,360,21600,0,0,94,1776,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,169 +17 560 . C <*> 0 . DP=7;I16=5,2,0,0,230,8132,0,0,420,25200,0,0,94,1760,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,181 +17 561 . A <*> 0 . DP=7;I16=5,2,0,0,254,9682,0,0,420,25200,0,0,95,1753,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,194 +17 562 . C <*> 0 . DP=7;I16=5,2,0,0,243,8835,0,0,420,25200,0,0,96,1756,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,187 +17 563 . A <*> 0 . DP=7;I16=5,2,0,0,227,8179,0,0,420,25200,0,0,97,1769,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,179 +17 564 . C <*> 0 . DP=7;I16=5,2,0,0,233,8027,0,0,420,25200,0,0,98,1792,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,182 +17 565 . G <*> 0 . DP=7;I16=5,2,0,0,195,5883,0,0,420,25200,0,0,99,1825,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,154 +17 566 . C <*> 0 . DP=7;I16=5,1,0,0,213,8153,0,0,360,21600,0,0,95,1843,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,167 +17 567 . C <*> 0 . DP=7;I16=5,2,0,0,251,9269,0,0,420,25200,0,0,101,1921,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,196 +17 568 . C <*> 0 . DP=7;I16=4,2,0,0,231,9031,0,0,360,21600,0,0,87,1759,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,189 +17 569 . T <*> 0 . DP=7;I16=5,2,0,0,277,11475,0,0,420,25200,0,0,103,2057,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,213 +17 570 . T <*> 0 . DP=7;I16=5,2,0,0,250,9228,0,0,420,25200,0,0,104,2140,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,195 +17 571 . C <*> 0 . DP=7;I16=5,2,0,0,246,9120,0,0,420,25200,0,0,105,2233,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,193 +17 572 . A <*> 0 . DP=6;I16=5,1,0,0,229,8933,0,0,360,21600,0,0,107,2335,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,175 +17 573 . A <*> 0 . DP=6;I16=5,1,0,0,235,9257,0,0,360,21600,0,0,109,2445,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,178 +17 574 . C <*> 0 . DP=6;I16=5,1,0,0,227,8679,0,0,360,21600,0,0,110,2512,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,173 +17 575 . T <*> 0 . DP=5;I16=4,1,0,0,197,7967,0,0,300,18000,0,0,111,2535,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,163 +17 576 . G <*> 0 . DP=5;I16=4,1,0,0,182,6904,0,0,300,18000,0,0,112,2564,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,151 +17 577 . G <*> 0 . DP=5;I16=4,1,0,0,176,6414,0,0,300,18000,0,0,113,2599,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,146 +17 578 . G <*> 0 . DP=5;I16=4,1,0,0,182,6814,0,0,300,18000,0,0,114,2640,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,151 +17 579 . G <*> 0 . DP=5;I16=3,1,0,0,165,6829,0,0,240,14400,0,0,89,2011,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,145 +17 580 . A <*> 0 . DP=5;I16=4,1,0,0,189,7293,0,0,300,18000,0,0,114,2636,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,155 +17 581 . A <*> 0 . DP=5;I16=4,1,0,0,183,7019,0,0,300,18000,0,0,114,2640,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,153 +17 582 . C <*> 0 . DP=5;I16=4,1,0,0,182,6834,0,0,300,18000,0,0,114,2648,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,151 +17 583 . T <*> 0 . DP=5;I16=4,1,0,0,196,7912,0,0,300,18000,0,0,114,2660,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,163 +17 584 . C <*> 0 . DP=5;I16=4,1,0,0,191,7427,0,0,300,18000,0,0,114,2676,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,157 +17 585 . A <*> 0 . DP=5;I16=4,1,0,0,191,7395,0,0,300,18000,0,0,114,2696,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,157 +17 586 . T <*> 0 . DP=5;I16=4,1,0,0,189,7311,0,0,300,18000,0,0,113,2669,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,156 +17 587 . C <*> 0 . DP=5;I16=4,1,0,0,188,7274,0,0,300,18000,0,0,112,2644,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,155 +17 588 . A <*> 0 . DP=5;I16=4,1,0,0,202,8170,0,0,300,18000,0,0,111,2621,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,164 +17 589 . A <*> 0 . DP=5;I16=4,1,0,0,204,8332,0,0,300,18000,0,0,110,2600,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,165 +17 590 . C <*> 0 . DP=6;I16=4,2,0,0,212,7662,0,0,360,21600,0,0,109,2581,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,175 +17 591 . A <*> 0 . DP=6;I16=4,2,0,0,228,8752,0,0,360,21600,0,0,109,2565,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,188 +17 592 . A <*> 0 . DP=6;I16=4,2,0,0,219,8323,0,0,360,21600,0,0,109,2553,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,182 +17 593 . C <*> 0 . DP=6;I16=4,2,0,0,209,7587,0,0,360,21600,0,0,109,2545,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,174 +17 594 . A <*> 0 . DP=8;I16=5,3,0,0,276,9808,0,0,480,28800,0,0,109,2541,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,212 +17 595 . A <*> 0 . DP=8;I16=5,3,0,0,279,9913,0,0,480,28800,0,0,111,2543,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,213 +17 596 . A <*> 0 . DP=8;I16=5,3,0,0,304,11636,0,0,480,28800,0,0,113,2553,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,230 +17 597 . C <*> 0 . DP=8;I16=5,3,0,0,290,10586,0,0,480,28800,0,0,115,2571,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,220 +17 598 . T <*> 0 . DP=9;I16=5,3,0,0,314,12420,0,0,480,28800,0,0,117,2597,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,239 +17 599 . T <*> 0 . DP=9;I16=5,4,0,0,336,12628,0,0,540,32400,0,0,124,2656,0,0;QS=1,0;MQSB=0.974597;MQ0F=0 PL 0,27,247 +17 600 . G <*> 0 . DP=8;I16=4,4,0,0,303,11515,0,0,480,28800,0,0,128,2708,0,0;QS=1,0;MQSB=0.992367;MQ0F=0 PL 0,24,232 +17 601 . T <*> 0 . DP=8;I16=4,4,0,0,305,11697,0,0,480,28800,0,0,132,2768,0,0;QS=1,0;MQSB=0.992367;MQ0F=0 PL 0,24,235 +17 602 . G <*> 0 . DP=8;I16=4,4,0,0,298,11176,0,0,480,28800,0,0,136,2836,0,0;QS=1,0;MQSB=0.992367;MQ0F=0 PL 0,24,229 +17 603 . G <*> 0 . DP=8;I16=4,4,0,0,281,10235,0,0,480,28800,0,0,139,2863,0,0;QS=1,0;MQSB=0.992367;MQ0F=0 PL 0,24,219 +17 604 . T <*> 0 . DP=8;I16=3,4,0,0,265,10121,0,0,420,25200,0,0,117,2275,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,212 +17 605 . T <*> 0 . DP=8;I16=3,4,0,0,267,10303,0,0,420,25200,0,0,120,2322,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,214 +17 606 . T <*> 0 . DP=8;I16=4,4,0,0,278,9966,0,0,480,28800,0,0,148,3004,0,0;QS=1,0;MQSB=0.992367;MQ0F=0 PL 0,24,217 +17 607 . A <*> 0 . DP=8;I16=4,4,0,0,288,10428,0,0,480,28800,0,0,151,3071,0,0;QS=1,0;MQSB=0.992367;MQ0F=0 PL 0,24,222 +17 608 . C <*> 0 . DP=9;I16=4,5,0,0,287,9495,0,0,540,32400,0,0,154,3148,0,0;QS=1,0;MQSB=0.974597;MQ0F=0 PL 0,27,214 +17 609 . C <*> 0 . DP=9;I16=4,5,0,0,323,11717,0,0,540,32400,0,0,158,3236,0,0;QS=1,0;MQSB=0.974597;MQ0F=0 PL 0,27,238 +17 610 . C <*> 0 . DP=9;I16=4,5,0,0,335,12565,0,0,540,32400,0,0,162,3336,0,0;QS=1,0;MQSB=0.974597;MQ0F=0 PL 0,27,246 +17 611 . A <*> 0 . DP=9;I16=4,5,0,0,333,12435,0,0,540,32400,0,0,166,3448,0,0;QS=1,0;MQSB=0.974597;MQ0F=0 PL 0,27,246 +17 612 . C <*> 0 . DP=9;I16=4,5,0,0,340,12944,0,0,540,32400,0,0,170,3572,0,0;QS=1,0;MQSB=0.974597;MQ0F=0 PL 0,27,250 +17 613 . A <*> 0 . DP=9;I16=4,5,0,0,321,11719,0,0,540,32400,0,0,174,3708,0,0;QS=1,0;MQSB=0.974597;MQ0F=0 PL 0,27,239 +17 614 . C <*> 0 . DP=9;I16=4,5,0,0,328,12204,0,0,540,32400,0,0,178,3856,0,0;QS=1,0;MQSB=0.974597;MQ0F=0 PL 0,27,245 +17 615 . A <*> 0 . DP=9;I16=4,5,0,0,344,13326,0,0,540,32400,0,0,182,4016,0,0;QS=1,0;MQSB=0.974597;MQ0F=0 PL 0,27,254 +17 616 . A <*> 0 . DP=9;I16=4,5,0,0,350,13768,0,0,540,32400,0,0,185,4137,0,0;QS=1,0;MQSB=0.974597;MQ0F=0 PL 0,27,255 +17 617 . T <*> 0 . DP=9;I16=4,5,0,0,351,13831,0,0,540,32400,0,0,188,4268,0,0;QS=1,0;MQSB=0.974597;MQ0F=0 PL 0,27,255 +17 618 . G <*> 0 . DP=9;I16=4,5,0,0,323,11839,0,0,540,32400,0,0,191,4409,0,0;QS=1,0;MQSB=0.974597;MQ0F=0 PL 0,27,240 +17 619 . G <*> 0 . DP=9;I16=4,5,0,0,336,12598,0,0,540,32400,0,0,194,4560,0,0;QS=1,0;MQSB=0.974597;MQ0F=0 PL 0,27,247 +17 620 . A <*> 0 . DP=9;I16=4,5,0,0,346,13546,0,0,540,32400,0,0,194,4568,0,0;QS=1,0;MQSB=0.974597;MQ0F=0 PL 0,27,255 +17 621 . A <*> 0 . DP=9;I16=4,5,0,0,353,14067,0,0,540,32400,0,0,194,4580,0,0;QS=1,0;MQSB=0.974597;MQ0F=0 PL 0,27,255 +17 622 . G <*> 0 . DP=9;I16=4,5,0,0,339,12831,0,0,540,32400,0,0,194,4596,0,0;QS=1,0;MQSB=0.974597;MQ0F=0 PL 0,27,249 +17 623 . A <*> 0 . DP=9;I16=4,5,0,0,347,13467,0,0,540,32400,0,0,194,4616,0,0;QS=1,0;MQSB=0.974597;MQ0F=0 PL 0,27,255 +17 624 . C <*> 0 . DP=9;I16=4,5,0,0,325,12051,0,0,540,32400,0,0,193,4591,0,0;QS=1,0;MQSB=0.974597;MQ0F=0 PL 0,27,242 +17 625 . C <*> 0 . DP=9;I16=4,5,0,0,336,12700,0,0,540,32400,0,0,192,4572,0,0;QS=1,0;MQSB=0.974597;MQ0F=0 PL 0,27,249 +17 626 . A <*> 0 . DP=9;I16=4,5,0,0,337,12659,0,0,540,32400,0,0,191,4559,0,0;QS=1,0;MQSB=0.974597;MQ0F=0 PL 0,27,247 +17 627 . C <*> 0 . DP=9;I16=4,5,0,0,344,13286,0,0,540,32400,0,0,190,4552,0,0;QS=1,0;MQSB=0.974597;MQ0F=0 PL 0,27,255 +17 628 . T <*> 0 . DP=8;I16=3,5,0,0,329,13595,0,0,480,28800,0,0,190,4550,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,249 +17 629 . T <*> 0 . DP=8;I16=3,5,0,0,296,11158,0,0,480,28800,0,0,189,4503,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,226 +17 630 . A <*> 0 . DP=8;I16=3,5,0,0,308,12256,0,0,480,28800,0,0,188,4462,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,235 +17 631 . G <*> 0 . DP=8;I16=3,5,0,0,288,10864,0,0,480,28800,0,0,187,4427,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,223 +17 632 . C <*> 0 . DP=8;I16=3,5,0,0,291,10911,0,0,480,28800,0,0,186,4398,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,224 +17 633 . A <*> 0 . DP=8;I16=3,5,0,0,280,9994,0,0,480,28800,0,0,185,4375,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,214 +17 634 . A <*> 0 . DP=8;I16=3,5,0,0,301,11703,0,0,480,28800,0,0,183,4307,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,229 +17 635 . C <*> 0 . DP=8;I16=3,5,0,0,301,11435,0,0,480,28800,0,0,181,4243,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,229 +17 636 . A <*> 0 . DP=8;I16=3,5,0,0,322,12992,0,0,480,28800,0,0,178,4134,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,243 +17 637 . A <*> 0 . DP=8;I16=3,5,0,0,320,12852,0,0,480,28800,0,0,175,4031,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,242 +17 638 . A <*> 0 . DP=8;I16=3,5,0,0,314,12420,0,0,480,28800,0,0,172,3934,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,238 +17 639 . A <*> 0 . DP=8;I16=3,5,0,0,297,11189,0,0,480,28800,0,0,169,3843,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,227 +17 640 . A <*> 0 . DP=8;I16=3,5,0,0,313,12331,0,0,480,28800,0,0,166,3758,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,240 +17 641 . G <*> 0 . DP=8;I16=3,5,0,0,284,10334,0,0,480,28800,0,0,163,3679,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,218 +17 642 . G <*> 0 . DP=8;I16=3,5,0,0,288,10596,0,0,480,28800,0,0,160,3606,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,221 +17 643 . A <*> 0 . DP=8;I16=3,5,0,0,314,12368,0,0,480,28800,0,0,157,3539,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,237 +17 644 . C <*> 0 . DP=8;I16=3,5,0,0,267,9111,0,0,480,28800,0,0,154,3478,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,204 +17 645 . C <*> 0 . DP=8;I16=3,5,0,0,298,11200,0,0,480,28800,0,0,151,3423,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,226 +17 646 . A <*> 0 . DP=9;I16=3,6,0,0,317,11507,0,0,540,32400,0,0,148,3374,0,0;QS=1,0;MQSB=0.924584;MQ0F=0 PL 0,27,229 +17 647 . A <*> 0 . DP=10;I16=3,7,0,0,309,9951,0,0,600,36000,0,0,146,3332,0,0;QS=1,0;MQSB=0.916482;MQ0F=0 PL 0,30,213 +17 648 . A <*> 0 . DP=10;I16=3,7,0,0,277,8221,0,0,600,36000,0,0,145,3299,0,0;QS=1,0;MQSB=0.916482;MQ0F=0 PL 0,30,194 +17 649 . C <*> 0 . DP=9;I16=3,6,0,0,296,10124,0,0,540,32400,0,0,145,3275,0,0;QS=1,0;MQSB=0.924584;MQ0F=0 PL 0,27,217 +17 650 . T <*> 0 . DP=9;I16=3,5,0,0,293,11063,0,0,480,28800,0,0,120,2634,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,226 +17 651 . C <*> 0 . DP=9;I16=3,6,0,0,317,11335,0,0,540,32400,0,0,145,3251,0,0;QS=1,0;MQSB=0.924584;MQ0F=0 PL 0,27,229 +17 652 . C <*> 0 . DP=9;I16=2,6,0,0,295,10975,0,0,480,28800,0,0,144,3250,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,213 +17 653 . T <*> 0 . DP=8;I16=2,6,0,0,313,12301,0,0,480,28800,0,0,145,3259,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,225 +17 654 . G <*> 0 . DP=8;I16=2,6,0,0,306,11846,0,0,480,28800,0,0,146,3274,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,223 +17 655 . G <*> 0 . DP=8;I16=2,6,0,0,294,10942,0,0,480,28800,0,0,147,3295,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,213 +17 656 . T <*> 0 . DP=8;I16=2,6,0,0,293,10849,0,0,480,28800,0,0,148,3322,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,213 +17 657 . A <*> 0 . DP=8;I16=2,6,0,0,262,9218,0,0,480,28800,0,0,149,3355,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,191 +17 658 . C <*> 0 . DP=8;I16=2,6,0,0,292,10812,0,0,480,28800,0,0,150,3394,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,211 +17 659 . A <*> 0 . DP=8;I16=2,6,0,0,296,11228,0,0,480,28800,0,0,151,3439,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,216 +17 660 . T <*> 0 . DP=8;I16=2,6,0,0,295,11195,0,0,480,28800,0,0,152,3490,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,214 +17 661 . G <*> 0 . DP=7;I16=1,6,0,0,269,10375,0,0,420,25200,0,0,154,3546,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,188 +17 662 . C <*> 0 . DP=7;I16=1,6,0,0,264,10078,0,0,420,25200,0,0,156,3606,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,187 +17 663 . A <*> 0 . DP=7;I16=1,6,0,0,258,9846,0,0,420,25200,0,0,158,3670,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,186 +17 664 . A <*> 0 . DP=7;I16=1,6,0,0,260,9752,0,0,420,25200,0,0,160,3738,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,184 +17 665 . C <*> 0 . DP=7;I16=1,6,0,0,259,9715,0,0,420,25200,0,0,162,3810,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,184 +17 666 . T <*> 0 . DP=7;I16=1,6,0,0,276,10958,0,0,420,25200,0,0,163,3837,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,194 +17 667 . G <*> 0 . DP=7;I16=1,6,0,0,265,10139,0,0,420,25200,0,0,164,3870,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,188 +17 668 . A <*> 0 . DP=7;I16=1,6,0,0,264,10108,0,0,420,25200,0,0,165,3909,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,187 +17 669 . C <*> 0 . DP=7;I16=1,6,0,0,268,10318,0,0,420,25200,0,0,166,3954,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,189 +17 670 . A <*> 0 . DP=7;I16=1,6,0,0,289,11969,0,0,420,25200,0,0,164,3858,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,205 +17 671 . G <*> 0 . DP=7;I16=1,6,0,0,270,10482,0,0,420,25200,0,0,162,3774,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,191 +17 672 . A <*> 0 . DP=7;I16=1,6,0,0,264,10000,0,0,420,25200,0,0,159,3651,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,185 +17 673 . T <*> 0 . DP=7;I16=1,6,0,0,272,10602,0,0,420,25200,0,0,155,3487,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,192 +17 674 . G <*> 0 . DP=7;I16=1,6,0,0,263,9939,0,0,420,25200,0,0,151,3331,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,185 +17 675 . A <*> 0 . DP=7;I16=1,6,0,0,270,10454,0,0,420,25200,0,0,147,3183,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,189 +17 676 . A <*> 0 . DP=7;I16=1,6,0,0,265,10085,0,0,420,25200,0,0,143,3043,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,186 +17 677 . T <*> 0 . DP=7;I16=1,6,0,0,275,10823,0,0,420,25200,0,0,139,2911,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,192 +17 678 . C <*> 0 . DP=7;I16=1,6,0,0,271,10551,0,0,420,25200,0,0,135,2787,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,191 +17 679 . T <*> 0 . DP=7;I16=1,6,0,0,278,11086,0,0,420,25200,0,0,131,2671,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,195 +17 680 . C <*> 0 . DP=7;I16=1,6,0,0,259,9627,0,0,420,25200,0,0,127,2563,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,181 +17 681 . A <*> 0 . DP=7;I16=1,6,0,0,246,8758,0,0,420,25200,0,0,123,2463,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,174 +17 682 . A <*> 0 . DP=7;I16=1,6,0,0,247,8871,0,0,420,25200,0,0,119,2371,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,176 +17 683 . A <*> 0 . DP=7;I16=1,6,0,0,230,8064,0,0,420,25200,0,0,115,2287,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,167 +17 684 . C <*> 0 . DP=7;I16=1,6,0,0,203,6051,0,0,420,25200,0,0,110,2162,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,145 +17 685 . G <*> 0 . DP=7;I16=1,6,0,0,245,8825,0,0,420,25200,0,0,105,2047,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,175 +17 686 . C <*> 0 . DP=7;I16=1,6,0,0,257,9479,0,0,420,25200,0,0,100,1942,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,180 +17 687 . A <*> 0 . DP=7;I16=1,6,0,0,242,8624,0,0,420,25200,0,0,95,1847,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,174 +17 688 . T <*> 0 . DP=7;I16=1,6,0,0,264,10042,0,0,420,25200,0,0,90,1762,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,187 +17 689 . T <*> 0 . DP=7;I16=1,6,0,0,261,9799,0,0,420,25200,0,0,85,1687,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,185 +17 690 . C <*> 0 . DP=7;I16=1,6,0,0,234,7914,0,0,420,25200,0,0,80,1622,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,165 +17 691 . C <*> 0 . DP=6;I16=1,5,0,0,210,7444,0,0,360,21600,0,0,76,1566,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,161 +17 692 . T <*> 0 . DP=6;I16=1,5,0,0,212,7840,0,0,360,21600,0,0,72,1518,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,164 +17 693 . C <*> 0 . DP=7;I16=1,6,0,0,244,8576,0,0,420,25200,0,0,68,1478,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,172 +17 694 . C <*> 0 . DP=7;I16=1,6,0,0,208,6256,0,0,420,25200,0,0,65,1447,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,146 +17 695 . G <*> 0 . DP=5;I16=0,5,0,0,175,6167,0,0,300,18000,0,0,65,1423,0,0;QS=1,0;MQ0F=0 PL 0,15,124 +17 696 . T <*> 0 . DP=5;I16=0,5,0,0,200,8004,0,0,300,18000,0,0,66,1404,0,0;QS=1,0;MQ0F=0 PL 0,15,141 +17 697 . G <*> 0 . DP=5;I16=0,5,0,0,167,5661,0,0,300,18000,0,0,67,1391,0,0;QS=1,0;MQ0F=0 PL 0,15,120 +17 698 . T <*> 0 . DP=5;I16=0,5,0,0,185,6863,0,0,300,18000,0,0,68,1384,0,0;QS=1,0;MQ0F=0 PL 0,15,131 +17 699 . G <*> 0 . DP=6;I16=0,5,0,0,186,6958,0,0,300,18000,0,0,69,1383,0,0;QS=1,0;MQ0F=0 PL 0,15,132 +17 700 . A <*> 0 . DP=6;I16=0,6,0,0,230,8860,0,0,329,18841,0,0,74,1404,0,0;QS=1,0;MQ0F=0 PL 0,18,148 +17 701 . A <*> 0 . DP=6;I16=0,6,0,0,221,8249,0,0,329,18841,0,0,76,1424,0,0;QS=1,0;MQ0F=0 PL 0,18,144 +17 702 . A <*> 0 . DP=6;I16=0,6,0,0,249,10353,0,0,329,18841,0,0,78,1452,0,0;QS=1,0;MQ0F=0 PL 0,18,159 +17 703 . G <*> 0 . DP=6;I16=0,6,0,0,222,8300,0,0,329,18841,0,0,80,1488,0,0;QS=1,0;MQ0F=0 PL 0,18,144 +17 704 . A <*> 0 . DP=6;I16=0,6,0,0,211,7523,0,0,329,18841,0,0,82,1532,0,0;QS=1,0;MQ0F=0 PL 0,18,139 +17 705 . A <*> 0 . DP=6;I16=0,6,0,0,242,9832,0,0,329,18841,0,0,84,1584,0,0;QS=1,0;MQ0F=0 PL 0,18,157 +17 706 . G <*> 0 . DP=6;I16=0,6,0,0,203,6969,0,0,329,18841,0,0,86,1644,0,0;QS=1,0;MQ0F=0 PL 0,18,131 +17 707 . C <*> 0 . DP=6;I16=0,6,0,0,200,6874,0,0,329,18841,0,0,88,1712,0,0;QS=1,0;MQ0F=0 PL 0,18,134 +17 708 . C <*> 0 . DP=6;I16=0,6,0,0,169,4803,0,0,329,18841,0,0,90,1788,0,0;QS=1,0;MQ0F=0 PL 0,18,110 +17 709 . G <*> 0 . DP=5;I16=0,5,0,0,182,6858,0,0,269,15241,0,0,93,1871,0,0;QS=1,0;MQ0F=0 PL 0,15,132 +17 710 . G <*> 0 . DP=5;I16=0,5,0,0,164,5932,0,0,269,15241,0,0,96,1960,0,0;QS=1,0;MQ0F=0 PL 0,15,122 +17 711 . A <*> 0 . DP=6;I16=0,6,0,0,216,7950,0,0,298,16082,0,0,124,2680,0,0;QS=1,0;MQ0F=0 PL 0,18,142 +17 712 . C <*> 0 . DP=6;I16=0,6,0,0,228,8740,0,0,298,16082,0,0,127,2781,0,0;QS=1,0;MQ0F=0 PL 0,18,146 +17 713 . T <*> 0 . DP=6;I16=0,6,0,0,225,8639,0,0,298,16082,0,0,130,2888,0,0;QS=1,0;MQ0F=0 PL 0,18,149 +17 714 . C <*> 0 . DP=6;I16=0,5,0,0,173,6121,0,0,269,15241,0,0,108,2376,0,0;QS=1,0;MQ0F=0 PL 0,15,125 +17 715 . A <*> 0 . DP=6;I16=0,5,0,0,162,5642,0,0,269,15241,0,0,117,2759,0,0;QS=1,0;MQ0F=0 PL 0,15,120 +17 716 . C <*> 0 . DP=6;I16=0,6,0,0,215,7981,0,0,298,16082,0,0,139,3245,0,0;QS=1,0;MQ0F=0 PL 0,18,145 +17 717 . A <*> 0 . DP=6;I16=0,6,0,0,229,9051,0,0,298,16082,0,0,142,3376,0,0;QS=1,0;MQ0F=0 PL 0,18,153 +17 718 . G <*> 0 . DP=6;I16=0,6,0,0,209,7521,0,0,298,16082,0,0,145,3513,0,0;QS=1,0;MQ0F=0 PL 0,18,139 +17 719 . G <*> 0 . DP=6;I16=0,4,0,0,154,6026,0,0,240,14400,0,0,99,2451,0,0;QS=1,0;MQ0F=0 PL 0,12,120 +17 720 . G <*> 0 . DP=6;I16=0,6,0,0,236,9324,0,0,298,16082,0,0,149,3701,0,0;QS=1,0;MQ0F=0 PL 0,18,147 +17 721 . C <*> 0 . DP=6;I16=0,6,0,0,227,8683,0,0,298,16082,0,0,150,3750,0,0;QS=1,0;MQ0F=0 PL 0,18,147 +17 722 . A <*> 0 . DP=6;I16=0,6,0,0,218,8102,0,0,298,16082,0,0,149,3701,0,0;QS=1,0;MQ0F=0 PL 0,18,143 +17 723 . A <*> 0 . DP=6;I16=0,5,0,0,196,7704,0,0,269,15241,0,0,122,2980,0,0;QS=1,0;MQ0F=0 PL 0,15,135 +17 724 . C <*> 0 . DP=6;I16=0,6,0,0,216,8000,0,0,298,16082,0,0,145,3513,0,0;QS=1,0;MQ0F=0 PL 0,18,140 +17 725 . A <*> 0 . DP=6;I16=0,6,0,0,211,7579,0,0,298,16082,0,0,143,3425,0,0;QS=1,0;MQ0F=0 PL 0,18,137 +17 726 . C <*> 0 . DP=6;I16=0,6,0,0,199,6927,0,0,298,16082,0,0,141,3341,0,0;QS=1,0;MQ0F=0 PL 0,18,136 +17 727 . A C,<*> 0 . DP=6;I16=0,5,0,1,173,6285,17,289,269,15241,29,841,114,2636,25,625;QS=0.908108,0.0918919,0;SGB=-0.379885;RPB=1;MQB=1;BQB=1;MQ0F=0 PL 0,1,109,15,112,119 +17 728 . C <*> 0 . DP=6;I16=0,6,0,0,214,7890,0,0,298,16082,0,0,137,3185,0,0;QS=1,0;MQ0F=0 PL 0,18,142 +17 729 . T <*> 0 . DP=6;I16=0,6,0,0,215,7867,0,0,298,16082,0,0,135,3113,0,0;QS=1,0;MQ0F=0 PL 0,18,142 +17 730 . A <*> 0 . DP=6;I16=0,5,0,0,187,7165,0,0,269,15241,0,0,108,2420,0,0;QS=1,0;MQ0F=0 PL 0,15,135 +17 731 . T <*> 0 . DP=6;I16=0,6,0,0,219,8327,0,0,298,16082,0,0,131,2981,0,0;QS=1,0;MQ0F=0 PL 0,18,148 +17 732 . C <*> 0 . DP=6;I16=0,5,0,0,178,6478,0,0,269,15241,0,0,104,2296,0,0;QS=1,0;MQ0F=0 PL 0,15,129 +17 733 . T <*> 0 . DP=6;I16=0,5,0,0,186,7036,0,0,269,15241,0,0,102,2240,0,0;QS=1,0;MQ0F=0 PL 0,15,134 +17 734 . G <*> 0 . DP=6;I16=0,6,0,0,217,7975,0,0,298,16082,0,0,125,2813,0,0;QS=1,0;MQ0F=0 PL 0,18,139 +17 735 . A <*> 0 . DP=7;I16=0,6,0,0,224,8474,0,0,329,18841,0,0,98,2140,0,0;QS=1,0;MQ0F=0 PL 0,18,148 +17 736 . C <*> 0 . DP=7;I16=0,6,0,0,233,9137,0,0,329,18841,0,0,97,2097,0,0;QS=1,0;MQ0F=0 PL 0,18,152 +17 737 . T <*> 0 . DP=7;I16=0,7,0,0,235,8339,0,0,358,19682,0,0,121,2685,0,0;QS=1,0;MQ0F=0 PL 0,21,149 +17 738 . G <*> 0 . DP=7;I16=0,6,0,0,220,8128,0,0,329,18841,0,0,95,2029,0,0;QS=1,0;MQ0F=0 PL 0,18,141 +17 739 . T <*> 0 . DP=7;I16=0,7,0,0,256,9646,0,0,358,19682,0,0,119,2629,0,0;QS=1,0;MQ0F=0 PL 0,21,155 +17 740 . T <*> 0 . DP=7;I16=0,7,0,0,248,9042,0,0,358,19682,0,0,118,2610,0,0;QS=1,0;MQ0F=0 PL 0,21,155 +17 741 . T <*> 0 . DP=7;I16=0,7,0,0,244,8970,0,0,358,19682,0,0,116,2548,0,0;QS=1,0;MQ0F=0 PL 0,21,151 +17 742 . C <*> 0 . DP=7;I16=0,6,0,0,200,6968,0,0,329,18841,0,0,89,1869,0,0;QS=1,0;MQ0F=0 PL 0,18,136 +17 743 . A <*> 0 . DP=7;I16=0,6,0,0,189,6467,0,0,329,18841,0,0,87,1823,0,0;QS=1,0;MQ0F=0 PL 0,18,131 +17 744 . T <*> 0 . DP=7;I16=0,7,0,0,261,9915,0,0,358,19682,0,0,110,2410,0,0;QS=1,0;MQ0F=0 PL 0,21,154 +17 745 . G <*> 0 . DP=8;I16=1,7,0,0,273,9633,0,0,418,23282,0,0,108,2380,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,178 +17 746 . G <*> 0 . DP=8;I16=1,7,0,0,274,9756,0,0,418,23282,0,0,107,2359,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,178 +17 747 . G <*> 0 . DP=7;I16=1,6,0,0,248,9012,0,0,358,19682,0,0,107,2347,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,174 +17 748 . A <*> 0 . DP=6;I16=1,5,0,0,207,7619,0,0,298,16082,0,0,108,2342,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,159 +17 749 . A <*> 0 . DP=6;I16=1,5,0,0,216,7972,0,0,298,16082,0,0,109,2343,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,164 +17 750 . A <*> 0 . DP=6;I16=1,4,0,0,197,7891,0,0,269,15241,0,0,95,2125,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,161 +17 751 . G <*> 0 . DP=6;I16=1,5,0,0,190,6410,0,0,298,16082,0,0,111,2363,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,150 +17 752 . T <*> 0 . DP=6;I16=1,5,0,0,184,5942,0,0,298,16082,0,0,112,2382,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,143 +17 753 . C <*> 0 . DP=6;I16=1,5,0,0,208,7512,0,0,298,16082,0,0,113,2407,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,158 +17 754 . T <*> 0 . DP=6;I16=1,5,0,0,234,9250,0,0,298,16082,0,0,114,2438,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,172 +17 755 . G <*> 0 . DP=6;I16=1,5,0,0,220,8164,0,0,298,16082,0,0,115,2475,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,162 +17 756 . G <*> 0 . DP=6;I16=1,5,0,0,200,7040,0,0,298,16082,0,0,116,2518,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,157 +17 757 . A <*> 0 . DP=6;I16=1,4,0,0,187,7063,0,0,269,15241,0,0,92,1942,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,152 +17 758 . A <*> 0 . DP=6;I16=1,5,0,0,205,7219,0,0,298,16082,0,0,118,2622,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,156 +17 759 . A <*> 0 . DP=6;I16=1,4,0,0,181,6927,0,0,269,15241,0,0,113,2647,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,151 +17 760 . C <*> 0 . DP=7;I16=1,5,0,0,161,4887,0,0,298,16082,0,0,120,2750,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,128 +17 761 . G <*> 0 . DP=7;I16=1,4,0,0,186,6990,0,0,300,18000,0,0,92,2132,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,153 +17 762 . G <*> 0 . DP=7;I16=1,6,0,0,249,9197,0,0,358,19682,0,0,122,2802,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,173 +17 763 . C A,<*> 0 . DP=7;I16=1,5,0,1,223,8479,15,225,329,18841,29,841,121,2833,2,4;QS=0.936975,0.0630252,0;SGB=-0.379885;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL 0,6,158,18,161,165 +17 764 . A <*> 0 . DP=7;I16=1,5,0,0,211,7679,0,0,329,18841,0,0,99,2253,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,163 +17 765 . A <*> 0 . DP=7;I16=1,5,0,0,230,8938,0,0,329,18841,0,0,125,2925,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,169 +17 766 . C <*> 0 . DP=6;I16=1,5,0,0,219,8097,0,0,329,18841,0,0,127,2977,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,164 +17 767 . A <*> 0 . DP=6;I16=1,5,0,0,187,6311,0,0,329,18841,0,0,129,3033,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,148 +17 768 . C <*> 0 . DP=6;I16=1,5,0,0,237,9391,0,0,329,18841,0,0,131,3093,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,173 +17 769 . C <*> 0 . DP=6;I16=1,5,0,0,238,9482,0,0,329,18841,0,0,132,3108,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,173 +17 770 . A <*> 0 . DP=6;I16=1,5,0,0,233,9073,0,0,329,18841,0,0,133,3129,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,171 +17 771 . T <*> 0 . DP=6;I16=1,5,0,0,243,9941,0,0,329,18841,0,0,132,3056,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,177 +17 772 . T <*> 0 . DP=6;I16=1,5,0,0,242,9776,0,0,329,18841,0,0,130,2940,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,176 +17 773 . G <*> 0 . DP=6;I16=1,5,0,0,233,9111,0,0,329,18841,0,0,128,2832,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,175 +17 774 . A <*> 0 . DP=6;I16=1,5,0,0,246,10094,0,0,329,18841,0,0,126,2732,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,179 +17 775 . G <*> 0 . DP=6;I16=1,5,0,0,237,9391,0,0,329,18841,0,0,124,2640,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,177 +17 776 . A <*> 0 . DP=6;I16=1,5,0,0,228,8798,0,0,329,18841,0,0,122,2556,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,169 +17 777 . C <*> 0 . DP=6;I16=1,5,0,0,221,8245,0,0,329,18841,0,0,120,2480,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,165 +17 778 . A <*> 0 . DP=6;I16=1,5,0,0,246,10108,0,0,329,18841,0,0,118,2412,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,181 +17 779 . G <*> 0 . DP=6;I16=1,5,0,0,219,8227,0,0,329,18841,0,0,116,2352,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,170 +17 780 . A <*> 0 . DP=6;I16=1,5,0,0,217,7995,0,0,329,18841,0,0,114,2300,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,166 +17 781 . A <*> 0 . DP=6;I16=1,4,0,0,196,7720,0,0,300,18000,0,0,97,2031,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,159 +17 782 . A <*> 0 . DP=6;I16=1,5,0,0,223,8435,0,0,329,18841,0,0,110,2220,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,171 +17 783 . A <*> 0 . DP=7;I16=1,6,0,0,248,9014,0,0,389,22441,0,0,108,2192,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,178 +17 784 . C <*> 0 . DP=7;I16=1,6,0,0,259,9613,0,0,389,22441,0,0,107,2173,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,178 +17 785 . A <*> 0 . DP=7;I16=1,6,0,0,278,11086,0,0,389,22441,0,0,106,2164,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,187 +17 786 . G <*> 0 . DP=7;I16=1,6,0,0,256,9458,0,0,389,22441,0,0,104,2114,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,180 +17 787 . G <*> 0 . DP=7;I16=1,6,0,0,254,9236,0,0,389,22441,0,0,102,2072,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,175 +17 788 . T <*> 0 . DP=7;I16=1,6,0,0,273,10665,0,0,389,22441,0,0,100,2038,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,188 +17 789 . G <*> 0 . DP=7;I16=1,6,0,0,262,9868,0,0,389,22441,0,0,98,2012,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,183 +17 790 . A <*> 0 . DP=7;I16=1,6,0,0,295,12443,0,0,389,22441,0,0,96,1994,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,201 +17 791 . G <*> 0 . DP=7;I16=1,6,0,0,252,9098,0,0,389,22441,0,0,94,1984,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,172 +17 792 . T <*> 0 . DP=7;I16=1,6,0,0,251,9043,0,0,389,22441,0,0,92,1982,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,172 +17 793 . G <*> 0 . DP=7;I16=1,6,0,0,247,8777,0,0,389,22441,0,0,90,1988,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,170 +17 794 . G <*> 0 . DP=6;I16=1,5,0,0,219,8009,0,0,329,18841,0,0,89,2001,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,161 +17 795 . T <*> 0 . DP=6;I16=1,5,0,0,215,7839,0,0,329,18841,0,0,88,2020,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,160 +17 796 . T <*> 0 . DP=5;I16=1,4,0,0,184,6874,0,0,269,15241,0,0,88,2044,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,150 +17 797 . G <*> 0 . DP=4;I16=1,3,0,0,154,5958,0,0,240,14400,0,0,89,2071,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,135 +17 798 . C <*> 0 . DP=4;I16=1,3,0,0,143,5191,0,0,240,14400,0,0,90,2100,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,126 +17 799 . C <*> 0 . DP=4;I16=1,3,0,0,156,6106,0,0,240,14400,0,0,91,2131,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,137 +17 800 . T <*> 0 . DP=4;I16=1,3,0,0,158,6300,0,0,240,14400,0,0,92,2164,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,139 +17 801 . G <*> 0 . DP=4;I16=1,3,0,0,164,6742,0,0,240,14400,0,0,93,2199,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,145 +17 802 . G <*> 0 . DP=4;I16=1,3,0,0,155,6075,0,0,240,14400,0,0,94,2236,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,137 +17 803 . G <*> 0 . DP=4;I16=1,3,0,0,154,5956,0,0,240,14400,0,0,95,2275,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,136 +17 804 . G <*> 0 . DP=4;I16=1,3,0,0,157,6185,0,0,240,14400,0,0,96,2316,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,138 +17 805 . C <*> 0 . DP=4;I16=1,3,0,0,147,5417,0,0,240,14400,0,0,97,2359,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,128 +17 806 . C <*> 0 . DP=4;I16=1,3,0,0,137,4781,0,0,240,14400,0,0,98,2404,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,122 +17 807 . A <*> 0 . DP=4;I16=1,3,0,0,166,6930,0,0,240,14400,0,0,99,2451,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,146 +17 808 . G <*> 0 . DP=4;I16=1,3,0,0,155,6029,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,136 +17 809 . G <*> 0 . DP=4;I16=1,3,0,0,155,6053,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,136 +17 810 . G <*> 0 . DP=4;I16=1,3,0,0,150,5676,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,132 +17 811 . A <*> 0 . DP=4;I16=1,3,0,0,159,6323,0,0,240,14400,0,0,99,2451,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,139 +17 812 . A <*> 0 . DP=4;I16=1,3,0,0,157,6231,0,0,240,14400,0,0,98,2404,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,139 +17 813 . C <*> 0 . DP=4;I16=1,3,0,0,157,6195,0,0,240,14400,0,0,97,2359,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,138 +17 814 . T <*> 0 . DP=4;I16=1,3,0,0,170,7226,0,0,240,14400,0,0,96,2316,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,148 +17 815 . T <*> 0 . DP=4;I16=1,3,0,0,163,6687,0,0,240,14400,0,0,95,2275,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,143 +17 816 . T <*> 0 . DP=4;I16=1,3,0,0,154,5954,0,0,240,14400,0,0,94,2236,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,136 +17 817 . C <*> 0 . DP=4;I16=1,3,0,0,140,5032,0,0,240,14400,0,0,93,2199,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,124 +17 818 . T <*> 0 . DP=4;I16=1,3,0,0,163,6657,0,0,240,14400,0,0,92,2164,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,143 +17 819 . G <*> 0 . DP=4;I16=1,3,0,0,161,6481,0,0,240,14400,0,0,91,2131,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,142 +17 820 . G <*> 0 . DP=4;I16=1,3,0,0,154,5958,0,0,240,14400,0,0,90,2100,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,135 +17 821 . G <*> 0 . DP=4;I16=1,3,0,0,161,6493,0,0,240,14400,0,0,88,2022,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,142 +17 822 . G <*> 0 . DP=4;I16=1,3,0,0,144,5218,0,0,240,14400,0,0,86,1948,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,127 +17 823 . T <*> 0 . DP=4;I16=1,3,0,0,146,5614,0,0,240,14400,0,0,84,1878,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,127 +17 824 . C <*> 0 . DP=4;I16=0,3,0,0,117,4569,0,0,180,10800,0,0,61,1371,0,0;QS=1,0;MQ0F=0 PL 0,9,98 +17 825 . A <*> 0 . DP=4;I16=1,3,0,0,132,4446,0,0,240,14400,0,0,80,1750,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,116 +17 826 . T <*> 0 . DP=4;I16=1,3,0,0,133,4477,0,0,240,14400,0,0,78,1692,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,117 +17 827 . A <*> 0 . DP=4;I16=1,3,0,0,139,4901,0,0,240,14400,0,0,76,1638,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,123 +17 828 . T C,<*> 0 . DP=4;I16=0,0,1,3,0,0,135,4719,0,0,240,14400,0,0,74,1588;QS=0,1,0;VDB=0.292086;SGB=-0.556411;MQSB=1;MQ0F=0 PL 120,12,0,120,12,120 +17 829 . T <*> 0 . DP=4;I16=1,3,0,0,149,5635,0,0,240,14400,0,0,72,1542,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,132 +17 830 . C <*> 0 . DP=4;I16=1,3,0,0,153,5865,0,0,240,14400,0,0,70,1500,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,134 +17 831 . T <*> 0 . DP=4;I16=1,3,0,0,151,5761,0,0,240,14400,0,0,68,1462,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,133 +17 832 . C <*> 0 . DP=4;I16=1,3,0,0,139,4905,0,0,240,14400,0,0,66,1428,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,123 +17 833 . T <*> 0 . DP=5;I16=1,3,0,0,125,4311,0,0,240,14400,0,0,64,1398,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,113 +17 834 . G A,<*> 0 . DP=5;I16=0,0,1,2,0,0,94,2994,0,0,180,10800,0,0,61,1371;QS=0,1,0;VDB=0.309755;SGB=-0.511536;MQSB=1;MQ0F=0 PL 89,9,0,89,9,89 +17 835 . T <*> 0 . DP=5;I16=1,3,0,0,107,3515,0,0,240,14400,0,0,62,1354,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,98 +17 836 . G <*> 0 . DP=4;I16=1,3,0,0,148,5478,0,0,240,14400,0,0,61,1291,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,130 +17 837 . T <*> 0 . DP=4;I16=1,3,0,0,161,6499,0,0,240,14400,0,0,60,1234,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,143 +17 838 . T <*> 0 . DP=4;I16=1,3,0,0,153,5859,0,0,240,14400,0,0,59,1183,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,134 +17 839 . G <*> 0 . DP=5;I16=1,3,0,0,161,6491,0,0,240,14400,0,0,58,1138,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,142 +17 840 . A <*> 0 . DP=6;I16=2,4,0,0,220,8190,0,0,360,21600,0,0,69,1243,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,180 +17 841 . T <*> 0 . DP=6;I16=2,4,0,0,225,8485,0,0,360,21600,0,0,70,1236,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,185 +17 842 . T <*> 0 . DP=6;I16=2,4,0,0,213,7643,0,0,360,21600,0,0,71,1239,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,175 +17 843 . C <*> 0 . DP=6;I16=2,4,0,0,194,6400,0,0,360,21600,0,0,72,1252,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,160 +17 844 . T <*> 0 . DP=6;I16=2,4,0,0,232,8996,0,0,360,21600,0,0,73,1275,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,189 +17 845 . G <*> 0 . DP=7;I16=3,4,0,0,244,8572,0,0,420,25200,0,0,74,1308,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,196 +17 846 . G <*> 0 . DP=6;I16=2,4,0,0,200,6776,0,0,360,21600,0,0,77,1351,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,164 +17 847 . T <*> 0 . DP=6;I16=2,4,0,0,183,5629,0,0,360,21600,0,0,80,1404,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,149 +17 848 . G <*> 0 . DP=6;I16=2,4,0,0,202,6952,0,0,360,21600,0,0,83,1467,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,167 +17 849 . G <*> 0 . DP=6;I16=2,3,0,0,160,5230,0,0,300,18000,0,0,65,1099,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,140 +17 850 . T <*> 0 . DP=6;I16=2,4,0,0,178,5468,0,0,360,21600,0,0,89,1623,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,147 +17 851 . G <*> 0 . DP=6;I16=2,4,0,0,189,6065,0,0,360,21600,0,0,92,1716,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,156 +17 852 . G <*> 0 . DP=6;I16=2,3,0,0,167,5669,0,0,300,18000,0,0,76,1458,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,146 +17 853 . A <*> 0 . DP=6;I16=2,4,0,0,200,6944,0,0,360,21600,0,0,98,1932,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,166 +17 854 . A <*> 0 . DP=6;I16=2,4,0,0,204,7078,0,0,360,21600,0,0,100,2004,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,168 +17 855 . A <*> 0 . DP=6;I16=2,4,0,0,179,6005,0,0,360,21600,0,0,102,2084,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,152 +17 856 . C <*> 0 . DP=6;I16=2,4,0,0,208,7382,0,0,360,21600,0,0,104,2172,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,172 +17 857 . A <*> 0 . DP=7;I16=3,4,0,0,242,8476,0,0,420,25200,0,0,106,2268,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,194 +17 858 . A <*> 0 . DP=7;I16=3,4,0,0,243,9003,0,0,420,25200,0,0,109,2373,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,198 +17 859 . G <*> 0 . DP=7;I16=3,4,0,0,254,9300,0,0,420,25200,0,0,110,2388,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,203 +17 860 . A <*> 0 . DP=7;I16=3,4,0,0,233,8223,0,0,420,25200,0,0,111,2413,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,190 +17 861 . C <*> 0 . DP=6;I16=3,3,0,0,189,6345,0,0,360,21600,0,0,113,2447,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,161 +17 862 . T <*> 0 . DP=6;I16=3,3,0,0,210,7702,0,0,360,21600,0,0,115,2489,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,177 +17 863 . G <*> 0 . DP=6;I16=3,3,0,0,214,7702,0,0,360,21600,0,0,117,2539,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,180 +17 864 . T <*> 0 . DP=6;I16=3,3,0,0,215,7757,0,0,360,21600,0,0,119,2597,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,180 +17 865 . C <*> 0 . DP=6;I16=3,3,0,0,210,7508,0,0,360,21600,0,0,121,2663,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,177 +17 866 . C <*> 0 . DP=6;I16=3,3,0,0,210,7530,0,0,360,21600,0,0,122,2686,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,177 +17 867 . C <*> 0 . DP=6;I16=3,3,0,0,222,8294,0,0,360,21600,0,0,123,2715,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,187 +17 868 . A <*> 0 . DP=6;I16=3,3,0,0,241,9703,0,0,360,21600,0,0,124,2750,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,202 +17 869 . G <*> 0 . DP=6;I16=3,3,0,0,223,8357,0,0,360,21600,0,0,125,2791,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,187 +17 870 . C <*> 0 . DP=6;I16=3,3,0,0,223,8379,0,0,360,21600,0,0,126,2838,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,187 +17 871 . C <*> 0 . DP=6;I16=3,3,0,0,228,8746,0,0,360,21600,0,0,126,2840,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,192 +17 872 . T <*> 0 . DP=6;I16=3,3,0,0,224,8456,0,0,360,21600,0,0,126,2846,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,188 +17 873 . G <*> 0 . DP=6;I16=3,3,0,0,217,7917,0,0,360,21600,0,0,126,2856,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,182 +17 874 . G <*> 0 . DP=6;I16=3,3,0,0,225,8529,0,0,360,21600,0,0,126,2870,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,189 +17 875 . G <*> 0 . DP=6;I16=3,3,0,0,188,6376,0,0,360,21600,0,0,126,2888,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,159 +17 876 . T <*> 0 . DP=6;I16=3,3,0,0,206,7160,0,0,360,21600,0,0,126,2910,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,173 +17 877 . G <*> 0 . DP=6;I16=3,3,0,0,208,7336,0,0,360,21600,0,0,126,2936,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,176 +17 878 . A <*> 0 . DP=6;I16=3,3,0,0,229,8757,0,0,360,21600,0,0,126,2966,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,191 +17 879 . T <*> 0 . DP=6;I16=3,3,0,0,221,8157,0,0,360,21600,0,0,126,3000,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,184 +17 880 . A <*> 0 . DP=6;I16=3,3,0,0,203,7047,0,0,360,21600,0,0,126,3038,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,172 +17 881 . C <*> 0 . DP=6;I16=3,3,0,0,218,8024,0,0,360,21600,0,0,126,3080,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,183 +17 882 . A <*> 0 . DP=6;I16=3,3,0,0,238,9516,0,0,360,21600,0,0,126,3126,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,200 +17 883 . G <*> 0 . DP=6;I16=3,3,0,0,208,7448,0,0,360,21600,0,0,125,3125,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,176 +17 884 . C <*> 0 . DP=5;I16=3,2,0,0,165,5551,0,0,300,18000,0,0,125,3125,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,144 +17 885 . G <*> 0 . DP=5;I16=3,2,0,0,149,4587,0,0,300,18000,0,0,125,3125,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,130 +17 886 . A <*> 0 . DP=5;I16=3,2,0,0,187,7107,0,0,300,18000,0,0,125,3125,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,163 +17 887 . G <*> 0 . DP=5;I16=3,2,0,0,170,6022,0,0,300,18000,0,0,125,3125,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,149 +17 888 . A <*> 0 . DP=5;I16=3,1,0,0,144,5302,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,127 +17 889 . C <*> 0 . DP=5;I16=3,2,0,0,184,6828,0,0,300,18000,0,0,125,3125,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,160 +17 890 . C <*> 0 . DP=5;I16=3,2,0,0,174,6238,0,0,300,18000,0,0,125,3125,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,152 +17 891 . C <*> 0 . DP=5;I16=3,2,0,0,189,7251,0,0,300,18000,0,0,125,3125,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,165 +17 892 . C <*> 0 . DP=5;I16=3,2,0,0,191,7399,0,0,300,18000,0,0,125,3125,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,167 +17 893 . A <*> 0 . DP=5;I16=3,2,0,0,191,7367,0,0,300,18000,0,0,125,3125,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,166 +17 894 . T <*> 0 . DP=5;I16=3,2,0,0,190,7260,0,0,300,18000,0,0,125,3125,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,165 +17 895 . C <*> 0 . DP=5;I16=3,2,0,0,186,7026,0,0,300,18000,0,0,125,3125,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,162 +17 896 . T <*> 0 . DP=5;I16=3,2,0,0,207,8587,0,0,300,18000,0,0,125,3125,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,180 +17 897 . C <*> 0 . DP=5;I16=3,2,0,0,191,7331,0,0,300,18000,0,0,125,3125,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,166 +17 898 . T <*> 0 . DP=5;I16=3,2,0,0,198,7966,0,0,300,18000,0,0,125,3125,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,172 +17 899 . A <*> 0 . DP=5;I16=3,2,0,0,168,6022,0,0,300,18000,0,0,125,3125,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,145 +17 900 . C <*> 0 . DP=5;I16=3,2,0,0,190,7260,0,0,300,18000,0,0,125,3125,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,166 +17 901 . C <*> 0 . DP=5;I16=3,2,0,0,193,7563,0,0,300,18000,0,0,125,3125,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,169 +17 902 . A <*> 0 . DP=5;I16=3,2,0,0,201,8083,0,0,300,18000,0,0,125,3125,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,174 +17 903 . A <*> 0 . DP=5;I16=3,2,0,0,197,7839,0,0,300,18000,0,0,125,3125,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,171 +17 904 . A <*> 0 . DP=5;I16=3,2,0,0,199,7985,0,0,300,18000,0,0,124,3076,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,174 +17 905 . A <*> 0 . DP=5;I16=3,2,0,0,197,7933,0,0,300,18000,0,0,123,3029,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,172 +17 906 . A <*> 0 . DP=5;I16=3,2,0,0,190,7450,0,0,300,18000,0,0,122,2984,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,166 +17 907 . A <*> 0 . DP=5;I16=3,2,0,0,189,7249,0,0,300,18000,0,0,121,2941,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,165 +17 908 . T <*> 0 . DP=5;I16=3,2,0,0,194,7554,0,0,300,18000,0,0,120,2900,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,168 +17 909 . T <*> 0 . DP=5;I16=3,2,0,0,185,6915,0,0,300,18000,0,0,118,2812,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,161 +17 910 . A <*> 0 . DP=5;I16=3,2,0,0,187,7029,0,0,300,18000,0,0,116,2728,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,162 +17 911 . A <*> 0 . DP=5;I16=3,2,0,0,193,7491,0,0,300,18000,0,0,114,2648,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,168 +17 912 . A <*> 0 . DP=5;I16=3,2,0,0,200,8024,0,0,300,18000,0,0,112,2572,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,173 +17 913 . A <*> 0 . DP=5;I16=3,2,0,0,197,7807,0,0,300,18000,0,0,110,2500,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,171 +17 914 . A <*> 0 . DP=5;I16=3,2,0,0,190,7228,0,0,300,18000,0,0,108,2432,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,164 +17 915 . T <*> 0 . DP=5;I16=3,2,0,0,189,7159,0,0,300,18000,0,0,106,2368,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,163 +17 916 . T <*> 0 . DP=5;I16=3,2,0,0,189,7169,0,0,300,18000,0,0,103,2259,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,164 +17 917 . A <*> 0 . DP=5;I16=3,2,0,0,197,7783,0,0,300,18000,0,0,100,2156,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,171 +17 918 . G <*> 0 . DP=5;I16=3,2,0,0,170,5848,0,0,300,18000,0,0,97,2059,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,147 +17 919 . C <*> 0 . DP=5;I16=3,2,0,0,175,6487,0,0,300,18000,0,0,94,1968,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,152 +17 920 . T <*> 0 . DP=5;I16=3,2,0,0,197,7805,0,0,300,18000,0,0,91,1883,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,171 +17 921 . G <*> 0 . DP=5;I16=3,2,0,0,188,7080,0,0,300,18000,0,0,87,1755,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,164 +17 922 . G <*> 0 . DP=5;I16=3,2,0,0,175,6227,0,0,300,18000,0,0,83,1635,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,151 +17 923 . G <*> 0 . DP=5;I16=3,2,0,0,165,5515,0,0,300,18000,0,0,79,1523,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,144 +17 924 . C <*> 0 . DP=5;I16=3,2,0,0,181,6579,0,0,300,18000,0,0,75,1419,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,157 +17 925 . A <*> 0 . DP=5;I16=3,2,0,0,187,7067,0,0,300,18000,0,0,71,1323,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,163 +17 926 . T <*> 0 . DP=5;I16=3,2,0,0,186,6994,0,0,300,18000,0,0,67,1235,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,161 +17 927 . G <*> 0 . DP=5;I16=3,2,0,0,182,6682,0,0,300,18000,0,0,63,1155,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,158 +17 928 . G <*> 0 . DP=5;I16=3,2,0,0,173,6013,0,0,300,18000,0,0,59,1083,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,150 +17 929 . T <*> 0 . DP=4;I16=3,1,0,0,146,5362,0,0,240,14400,0,0,56,1018,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,128 +17 930 . G <*> 0 . DP=4;I16=3,1,0,0,145,5287,0,0,240,14400,0,0,53,959,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,127 +17 931 . G <*> 0 . DP=4;I16=3,1,0,0,129,4185,0,0,240,14400,0,0,50,906,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,113 +17 932 . T <*> 0 . DP=4;I16=3,1,0,0,139,4863,0,0,240,14400,0,0,47,859,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,122 +17 933 . G <*> 0 . DP=4;I16=3,1,0,0,131,4299,0,0,240,14400,0,0,43,769,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,116 +17 934 . C <*> 0 . DP=3;I16=3,0,0,0,119,4721,0,0,180,10800,0,0,40,686,0,0;QS=1,0;MQ0F=0 PL 0,9,99 +17 935 . A <*> 0 . DP=3;I16=3,0,0,0,121,4881,0,0,180,10800,0,0,37,609,0,0;QS=1,0;MQ0F=0 PL 0,9,101 +17 936 . T <*> 0 . DP=3;I16=3,0,0,0,120,4800,0,0,180,10800,0,0,34,538,0,0;QS=1,0;MQ0F=0 PL 0,9,100 +17 937 . G <*> 0 . DP=4;I16=4,0,0,0,149,5589,0,0,240,14400,0,0,31,473,0,0;QS=1,0;MQ0F=0 PL 0,12,115 +17 938 . C <*> 0 . DP=4;I16=4,0,0,0,155,6013,0,0,240,14400,0,0,29,415,0,0;QS=1,0;MQ0F=0 PL 0,12,119 +17 939 . C <*> 0 . DP=4;I16=4,0,0,0,150,5634,0,0,240,14400,0,0,27,365,0,0;QS=1,0;MQ0F=0 PL 0,12,115 +17 940 . T <*> 0 . DP=4;I16=4,0,0,0,160,6438,0,0,240,14400,0,0,25,323,0,0;QS=1,0;MQ0F=0 PL 0,12,124 +17 941 . G <*> 0 . DP=3;I16=3,0,0,0,111,4113,0,0,180,10800,0,0,24,288,0,0;QS=1,0;MQ0F=0 PL 0,9,93 +17 942 . T <*> 0 . DP=3;I16=3,0,0,0,112,4194,0,0,180,10800,0,0,23,259,0,0;QS=1,0;MQ0F=0 PL 0,9,94 +17 943 . A <*> 0 . DP=3;I16=3,0,0,0,111,4133,0,0,180,10800,0,0,22,236,0,0;QS=1,0;MQ0F=0 PL 0,9,93 +17 944 . G <*> 0 . DP=3;I16=3,0,0,0,114,4338,0,0,180,10800,0,0,21,219,0,0;QS=1,0;MQ0F=0 PL 0,9,95 +17 945 . T <*> 0 . DP=3;I16=3,0,0,0,113,4273,0,0,180,10800,0,0,20,208,0,0;QS=1,0;MQ0F=0 PL 0,9,95 +17 946 . C <*> 0 . DP=2;I16=2,0,0,0,76,2938,0,0,120,7200,0,0,20,202,0,0;QS=1,0;MQ0F=0 PL 0,6,70 +17 947 . C <*> 0 . DP=2;I16=2,0,0,0,72,2624,0,0,120,7200,0,0,20,200,0,0;QS=1,0;MQ0F=0 PL 0,6,66 +17 948 . C <*> 0 . DP=2;I16=2,0,0,0,76,2890,0,0,120,7200,0,0,20,202,0,0;QS=1,0;MQ0F=0 PL 0,6,69 +17 949 . A <*> 0 . DP=2;I16=2,0,0,0,79,3125,0,0,120,7200,0,0,20,208,0,0;QS=1,0;MQ0F=0 PL 0,6,72 +17 950 . G <*> 0 . DP=2;I16=2,0,0,0,79,3121,0,0,120,7200,0,0,20,218,0,0;QS=1,0;MQ0F=0 PL 0,6,72 +17 951 . C <*> 0 . DP=2;I16=2,0,0,0,80,3200,0,0,120,7200,0,0,20,232,0,0;QS=1,0;MQ0F=0 PL 0,6,73 +17 952 . T <*> 0 . DP=2;I16=2,0,0,0,80,3218,0,0,120,7200,0,0,20,250,0,0;QS=1,0;MQ0F=0 PL 0,6,73 +17 953 . A <*> 0 . DP=2;I16=2,0,0,0,76,2888,0,0,120,7200,0,0,20,272,0,0;QS=1,0;MQ0F=0 PL 0,6,69 +17 954 . T <*> 0 . DP=2;I16=2,0,0,0,76,2888,0,0,120,7200,0,0,20,298,0,0;QS=1,0;MQ0F=0 PL 0,6,69 +17 955 . T <*> 0 . DP=2;I16=2,0,0,0,75,2813,0,0,120,7200,0,0,20,328,0,0;QS=1,0;MQ0F=0 PL 0,6,68 +17 956 . C <*> 0 . DP=2;I16=2,0,0,0,77,2965,0,0,120,7200,0,0,20,362,0,0;QS=1,0;MQ0F=0 PL 0,6,70 +17 957 . A <*> 0 . DP=2;I16=2,0,0,0,73,2677,0,0,120,7200,0,0,20,400,0,0;QS=1,0;MQ0F=0 PL 0,6,67 +17 958 . C <*> 0 . DP=1;I16=1,0,0,0,39,1521,0,0,60,3600,0,0,21,441,0,0;QS=1,0;MQ0F=0 PL 0,3,39 +17 959 . A <*> 0 . DP=1;I16=1,0,0,0,38,1444,0,0,60,3600,0,0,22,484,0,0;QS=1,0;MQ0F=0 PL 0,3,38 +17 960 . G <*> 0 . DP=1;I16=1,0,0,0,41,1681,0,0,60,3600,0,0,23,529,0,0;QS=1,0;MQ0F=0 PL 0,3,41 +17 961 . T <*> 0 . DP=1;I16=1,0,0,0,39,1521,0,0,60,3600,0,0,24,576,0,0;QS=1,0;MQ0F=0 PL 0,3,39 +17 962 . G <*> 0 . DP=1;I16=1,0,0,0,36,1296,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,36 +17 963 . C <*> 0 . DP=1;I16=1,0,0,0,40,1600,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,40 +17 964 . T <*> 0 . DP=1;I16=1,0,0,0,42,1764,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,42 +17 965 . G <*> 0 . DP=1;I16=1,0,0,0,40,1600,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,40 +17 966 . A <*> 0 . DP=1;I16=1,0,0,0,40,1600,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,40 +17 967 . G <*> 0 . DP=1;I16=1,0,0,0,41,1681,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,41 +17 968 . G <*> 0 . DP=1;I16=1,0,0,0,42,1764,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,42 +17 969 . T <*> 0 . DP=1;I16=1,0,0,0,31,961,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,31 +17 970 . G <*> 0 . DP=1;I16=1,0,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 +17 971 . G <*> 0 . DP=1;I16=1,0,0,0,38,1444,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,38 +17 972 . G <*> 0 . DP=1;I16=1,0,0,0,39,1521,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,39 +17 973 . A <*> 0 . DP=1;I16=1,0,0,0,42,1764,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,42 +17 974 . A <*> 0 . DP=1;I16=1,0,0,0,42,1764,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,42 +17 975 . G <*> 0 . DP=1;I16=1,0,0,0,42,1764,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,42 +17 976 . A <*> 0 . DP=1;I16=1,0,0,0,41,1681,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,41 +17 977 . T <*> 0 . DP=1;I16=1,0,0,0,37,1369,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,37 +17 978 . G <*> 0 . DP=1;I16=1,0,0,0,40,1600,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,40 +17 979 . C <*> 0 . DP=1;I16=1,0,0,0,41,1681,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,41 +17 980 . T <*> 0 . DP=1;I16=1,0,0,0,43,1849,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,43 +17 981 . T <*> 0 . DP=1;I16=1,0,0,0,41,1681,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,41 +17 982 . G <*> 0 . DP=1;I16=1,0,0,0,40,1600,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,40 +17 983 . A <*> 0 . DP=1;I16=1,0,0,0,42,1764,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,42 +17 984 . G <*> 0 . DP=1;I16=1,0,0,0,43,1849,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,43 +17 985 . C <*> 0 . DP=2;I16=1,1,0,0,65,2137,0,0,120,7200,0,0,25,625,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,65 +17 986 . C <*> 0 . DP=2;I16=1,1,0,0,69,2493,0,0,120,7200,0,0,26,626,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,69 +17 987 . C <*> 0 . DP=2;I16=1,1,0,0,69,2385,0,0,120,7200,0,0,27,629,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,69 +17 988 . A <*> 0 . DP=2;I16=1,1,0,0,82,3362,0,0,120,7200,0,0,28,634,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,82 +17 989 . G <*> 0 . DP=2;I16=1,1,0,0,80,3208,0,0,120,7200,0,0,29,641,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,80 +17 990 . G <*> 0 . DP=2;I16=1,1,0,0,83,3457,0,0,120,7200,0,0,30,650,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,83 +17 991 . A <*> 0 . DP=2;I16=1,1,0,0,80,3218,0,0,120,7200,0,0,31,661,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,80 +17 992 . G <*> 0 . DP=2;I16=1,1,0,0,76,2906,0,0,120,7200,0,0,32,674,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,76 +17 993 . T <*> 0 . DP=2;I16=1,1,0,0,73,2725,0,0,120,7200,0,0,33,689,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,73 +17 994 . T <*> 0 . DP=3;I16=2,1,0,0,109,3995,0,0,180,10800,0,0,34,706,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,103 +17 995 . C <*> 0 . DP=3;I16=2,1,0,0,117,4571,0,0,180,10800,0,0,36,726,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,110 +17 996 . A <*> 0 . DP=3;I16=2,1,0,0,120,4806,0,0,180,10800,0,0,38,750,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,113 +17 997 . A <*> 0 . DP=3;I16=2,1,0,0,128,5472,0,0,180,10800,0,0,40,778,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,121 +17 998 . G <*> 0 . DP=3;I16=2,1,0,0,122,4980,0,0,180,10800,0,0,42,810,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,115 +17 999 . G <*> 0 . DP=3;I16=2,1,0,0,118,4650,0,0,180,10800,0,0,44,846,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,111 +17 1000 . C <*> 0 . DP=3;I16=2,1,0,0,116,4490,0,0,180,10800,0,0,46,886,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,109 +17 1001 . T <*> 0 . DP=3;I16=2,1,0,0,129,5555,0,0,180,10800,0,0,48,930,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,122 +17 1002 . G <*> 0 . DP=3;I16=2,1,0,0,115,4459,0,0,180,10800,0,0,50,978,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,109 +17 1003 . C <*> 0 . DP=3;I16=2,1,0,0,108,4046,0,0,180,10800,0,0,52,1030,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,102 +17 1004 . A <*> 0 . DP=3;I16=2,1,0,0,104,3706,0,0,180,10800,0,0,54,1086,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,98 +17 1005 . A <*> 0 . DP=3;I16=2,1,0,0,120,4856,0,0,180,10800,0,0,56,1146,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,113 +17 1006 . T <*> 0 . DP=3;I16=2,1,0,0,122,4964,0,0,180,10800,0,0,58,1210,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,115 +17 1007 . G <*> 0 . DP=3;I16=2,1,0,0,120,4802,0,0,180,10800,0,0,60,1278,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,113 +17 1008 . A <*> 0 . DP=3;I16=2,1,0,0,126,5294,0,0,180,10800,0,0,62,1350,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,118 +17 1009 . G <*> 0 . DP=3;I16=2,1,0,0,123,5049,0,0,180,10800,0,0,64,1426,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,116 +17 1010 . C <*> 0 . DP=3;I16=2,1,0,0,121,4889,0,0,180,10800,0,0,66,1506,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,114 +17 1011 . T <*> 0 . DP=3;I16=2,1,0,0,125,5249,0,0,180,10800,0,0,67,1539,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,118 +17 1012 . A <*> 0 . DP=3;I16=2,1,0,0,120,4806,0,0,180,10800,0,0,68,1574,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,113 +17 1013 . T <*> 0 . DP=3;I16=2,1,0,0,122,4964,0,0,180,10800,0,0,68,1562,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,115 +17 1014 . G <*> 0 . DP=3;I16=2,1,0,0,120,4806,0,0,180,10800,0,0,68,1554,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,113 +17 1015 . A <*> 0 . DP=3;I16=2,1,0,0,116,4600,0,0,180,10800,0,0,68,1550,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,109 +17 1016 . T <*> 0 . DP=3;I16=2,1,0,0,108,4074,0,0,180,10800,0,0,68,1550,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,101 +17 1017 . T <*> 0 . DP=3;I16=2,1,0,0,112,4312,0,0,180,10800,0,0,68,1554,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,105 +17 1018 . G <*> 0 . DP=3;I16=2,1,0,0,97,3445,0,0,180,10800,0,0,68,1562,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,91 +17 1019 . C <*> 0 . DP=3;I16=2,1,0,0,111,4289,0,0,180,10800,0,0,68,1574,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,104 +17 1020 . G <*> 0 . DP=3;I16=2,1,0,0,92,2832,0,0,180,10800,0,0,67,1539,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,87 +17 1021 . C <*> 0 . DP=3;I16=2,1,0,0,99,3653,0,0,180,10800,0,0,66,1506,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,92 +17 1022 . C <*> 0 . DP=3;I16=2,1,0,0,116,4526,0,0,180,10800,0,0,65,1475,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,110 +17 1023 . A <*> 0 . DP=3;I16=2,1,0,0,119,4731,0,0,180,10800,0,0,64,1446,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,112 +17 1024 . C <*> 0 . DP=3;I16=2,1,0,0,112,4214,0,0,180,10800,0,0,63,1419,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,106 +17 1025 . T <*> 0 . DP=3;I16=2,1,0,0,124,5142,0,0,180,10800,0,0,62,1394,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,117 +17 1026 . G <*> 0 . DP=3;I16=2,1,0,0,120,4802,0,0,180,10800,0,0,61,1371,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,113 +17 1027 . C <*> 0 . DP=3;I16=2,1,0,0,117,4589,0,0,180,10800,0,0,60,1350,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,110 +17 1028 . A <*> 0 . DP=3;I16=2,1,0,0,106,3906,0,0,180,10800,0,0,59,1331,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,99 +17 1029 . C <*> 0 . DP=3;I16=2,1,0,0,118,4646,0,0,180,10800,0,0,58,1314,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,111 +17 1030 . T <*> 0 . DP=3;I16=2,1,0,0,130,5634,0,0,180,10800,0,0,57,1299,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,122 +17 1031 . T <*> 0 . DP=3;I16=2,1,0,0,120,4824,0,0,180,10800,0,0,56,1286,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,113 +17 1032 . T <*> 0 . DP=3;I16=2,1,0,0,118,4660,0,0,180,10800,0,0,55,1275,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,111 +17 1033 . G <*> 0 . DP=3;I16=2,1,0,0,107,3969,0,0,180,10800,0,0,54,1266,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,101 +17 1034 . G <*> 0 . DP=3;I16=2,1,0,0,108,3938,0,0,180,10800,0,0,53,1259,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,102 +17 1035 . C <*> 0 . DP=3;I16=2,1,0,0,100,3654,0,0,180,10800,0,0,52,1254,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,94 +17 1036 . C <*> 0 . DP=4;I16=3,1,0,0,153,5921,0,0,240,14400,0,0,51,1251,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,135 +17 1037 . T <*> 0 . DP=4;I16=3,1,0,0,157,6201,0,0,240,14400,0,0,51,1251,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,138 +17 1038 . G <*> 0 . DP=3;I16=2,1,0,0,114,4346,0,0,180,10800,0,0,52,1254,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,107 +17 1039 . G <*> 0 . DP=3;I16=2,1,0,0,117,4625,0,0,180,10800,0,0,53,1259,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,111 +17 1040 . A <*> 0 . DP=3;I16=2,1,0,0,113,4317,0,0,180,10800,0,0,54,1266,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,107 +17 1041 . C <*> 0 . DP=3;I16=2,1,0,0,116,4520,0,0,180,10800,0,0,55,1275,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,110 +17 1042 . A <*> 0 . DP=5;I16=4,1,0,0,178,6394,0,0,300,18000,0,0,56,1286,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,145 +17 1043 . A <*> 0 . DP=5;I16=4,1,0,0,195,7659,0,0,300,18000,0,0,59,1301,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,159 +17 1044 . C <*> 0 . DP=5;I16=4,1,0,0,185,6881,0,0,300,18000,0,0,62,1322,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,150 +17 1045 . A <*> 0 . DP=5;I16=4,1,0,0,191,7341,0,0,300,18000,0,0,65,1349,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,156 +17 1046 . G <*> 0 . DP=5;I16=4,1,0,0,194,7580,0,0,300,18000,0,0,68,1382,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,158 +17 1047 . A <*> 0 . DP=5;I16=4,1,0,0,204,8334,0,0,300,18000,0,0,71,1421,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,165 +17 1048 . G <*> 0 . DP=5;I16=4,1,0,0,191,7339,0,0,300,18000,0,0,74,1466,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,156 +17 1049 . C <*> 0 . DP=5;I16=4,1,0,0,198,7856,0,0,300,18000,0,0,77,1517,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,160 +17 1050 . A <*> 0 . DP=5;I16=3,1,0,0,158,6250,0,0,240,14400,0,0,66,1378,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,138 +17 1051 . A <*> 0 . DP=5;I16=4,1,0,0,182,6962,0,0,300,18000,0,0,83,1637,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,150 +17 1052 . A <*> 0 . DP=5;I16=4,1,0,0,185,7123,0,0,300,18000,0,0,86,1706,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,150 +17 1053 . A <*> 0 . DP=5;I16=4,1,0,0,186,7442,0,0,300,18000,0,0,89,1781,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,149 +17 1054 . C <*> 0 . DP=5;I16=4,1,0,0,187,7033,0,0,300,18000,0,0,92,1862,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,153 +17 1055 . C <*> 0 . DP=5;I16=4,1,0,0,191,7375,0,0,300,18000,0,0,95,1949,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,157 +17 1056 . C <*> 0 . DP=5;I16=4,1,0,0,198,7986,0,0,300,18000,0,0,98,2042,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,161 +17 1057 . T <*> 0 . DP=5;I16=4,1,0,0,197,7989,0,0,300,18000,0,0,101,2141,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,159 +17 1058 . G <*> 0 . DP=5;I16=4,1,0,0,190,7328,0,0,300,18000,0,0,104,2246,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,155 +17 1059 . T <*> 0 . DP=5;I16=4,1,0,0,185,6901,0,0,300,18000,0,0,107,2357,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,152 +17 1060 . C <*> 0 . DP=5;I16=4,1,0,0,198,7862,0,0,300,18000,0,0,110,2474,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,163 +17 1061 . T <*> 0 . DP=5;I16=4,1,0,0,193,7643,0,0,300,18000,0,0,112,2548,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,158 +17 1062 . C <*> 0 . DP=5;I16=4,1,0,0,201,8099,0,0,300,18000,0,0,113,2579,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,164 +17 1063 . T <*> 0 . DP=5;I16=4,1,0,0,204,8428,0,0,300,18000,0,0,114,2616,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,166 +17 1064 . A <*> 0 . DP=5;I16=4,1,0,0,201,8085,0,0,300,18000,0,0,115,2659,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,162 +17 1065 . A <*> 0 . DP=5;I16=4,1,0,0,212,9010,0,0,300,18000,0,0,116,2708,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,174 +17 1066 . A <*> 0 . DP=6;I16=5,1,0,0,234,9462,0,0,360,21600,0,0,117,2763,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,181 +17 1067 . A <*> 0 . DP=6;I16=5,1,0,0,235,9545,0,0,360,21600,0,0,119,2825,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,182 +17 1068 . A <*> 0 . DP=6;I16=5,1,0,0,235,9515,0,0,360,21600,0,0,119,2793,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,181 +17 1069 . A <*> 0 . DP=7;I16=6,1,0,0,247,9045,0,0,420,25200,0,0,119,2765,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,177 +17 1070 . A <*> 0 . DP=7;I16=6,1,0,0,261,9957,0,0,420,25200,0,0,119,2693,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,188 +17 1071 . G <*> 0 . DP=7;I16=6,1,0,0,274,10748,0,0,420,25200,0,0,119,2629,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,191 +17 1072 . A <*> 0 . DP=7;I16=6,1,0,0,276,10932,0,0,420,25200,0,0,119,2573,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,195 +17 1073 . A <*> 0 . DP=7;I16=6,1,0,0,283,11473,0,0,420,25200,0,0,119,2525,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,199 +17 1074 . A <*> 0 . DP=7;I16=6,1,0,0,287,11811,0,0,420,25200,0,0,119,2485,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,203 +17 1075 . A <*> 0 . DP=7;I16=6,1,0,0,282,11444,0,0,420,25200,0,0,119,2453,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,200 +17 1076 . G <*> 0 . DP=7;I16=6,1,0,0,261,9981,0,0,420,25200,0,0,119,2429,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,183 +17 1077 . A <*> 0 . DP=8;I16=7,1,0,0,315,12539,0,0,480,28800,0,0,119,2413,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,209 +17 1078 . A <*> 0 . DP=8;I16=7,1,0,0,322,13080,0,0,480,28800,0,0,120,2406,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,214 +17 1079 . A <*> 0 . DP=8;I16=7,1,0,0,311,12205,0,0,480,28800,0,0,121,2409,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,206 +17 1080 . A <*> 0 . DP=8;I16=7,1,0,0,331,13751,0,0,480,28800,0,0,122,2422,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,218 +17 1081 . G <*> 0 . DP=9;I16=8,1,0,0,342,13060,0,0,540,32400,0,0,123,2445,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,27,210 +17 1082 . A <*> 0 . DP=9;I16=8,1,0,0,354,14088,0,0,540,32400,0,0,125,2479,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,27,217 +17 1083 . A <*> 0 . DP=9;I16=8,1,0,0,354,14182,0,0,540,32400,0,0,127,2525,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,27,217 +17 1084 . A <*> 0 . DP=9;I16=8,1,0,0,348,13802,0,0,540,32400,0,0,129,2583,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,27,215 +17 1085 . A <*> 0 . DP=9;I16=8,1,0,0,346,13750,0,0,540,32400,0,0,131,2653,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,27,214 +17 1086 . A <*> 0 . DP=8;I16=8,0,0,0,309,12149,0,0,480,28800,0,0,134,2734,0,0;QS=1,0;MQ0F=0 PL 0,24,179 +17 1087 . C <*> 0 . DP=9;I16=9,0,0,0,319,11641,0,0,540,32400,0,0,137,2825,0,0;QS=1,0;MQ0F=0 PL 0,27,173 +17 1088 . T <*> 0 . DP=9;I16=9,0,0,0,378,15920,0,0,540,32400,0,0,141,2927,0,0;QS=1,0;MQ0F=0 PL 0,27,198 +17 1089 . C <*> 0 . DP=9;I16=9,0,0,0,351,13905,0,0,540,32400,0,0,145,3041,0,0;QS=1,0;MQ0F=0 PL 0,27,188 +17 1090 . A <*> 0 . DP=9;I16=9,0,0,0,348,13530,0,0,540,32400,0,0,149,3167,0,0;QS=1,0;MQ0F=0 PL 0,27,183 +17 1091 . C <*> 0 . DP=9;I16=9,0,0,0,333,12443,0,0,540,32400,0,0,153,3305,0,0;QS=1,0;MQ0F=0 PL 0,27,177 +17 1092 . T <*> 0 . DP=9;I16=9,0,0,0,378,15912,0,0,540,32400,0,0,156,3404,0,0;QS=1,0;MQ0F=0 PL 0,27,198 +17 1093 . G <*> 0 . DP=9;I16=9,0,0,0,348,13536,0,0,540,32400,0,0,159,3513,0,0;QS=1,0;MQ0F=0 PL 0,27,184 +17 1094 . G <*> 0 . DP=9;I16=8,0,0,0,325,13295,0,0,480,28800,0,0,155,3583,0,0;QS=1,0;MQ0F=0 PL 0,24,185 +17 1095 . A <*> 0 . DP=8;I16=8,0,0,0,310,12292,0,0,480,28800,0,0,165,3709,0,0;QS=1,0;MQ0F=0 PL 0,24,178 +17 1096 . T <*> 0 . DP=9;I16=9,0,0,0,331,12443,0,0,540,32400,0,0,168,3792,0,0;QS=1,0;MQ0F=0 PL 0,27,178 +17 1097 . A <*> 0 . DP=9;I16=9,0,0,0,330,12450,0,0,540,32400,0,0,172,3882,0,0;QS=1,0;MQ0F=0 PL 0,27,177 +17 1098 . T <*> 0 . DP=9;I16=9,0,0,0,356,14108,0,0,540,32400,0,0,176,3980,0,0;QS=1,0;MQ0F=0 PL 0,27,186 +17 1099 . G <*> 0 . DP=9;I16=9,0,0,0,346,13384,0,0,540,32400,0,0,180,4086,0,0;QS=1,0;MQ0F=0 PL 0,27,182 +17 1100 . A <*> 0 . DP=9;I16=9,0,0,0,363,14713,0,0,540,32400,0,0,184,4200,0,0;QS=1,0;MQ0F=0 PL 0,27,191 +17 1101 . A <*> 0 . DP=9;I16=9,0,0,0,377,15835,0,0,540,32400,0,0,188,4322,0,0;QS=1,0;MQ0F=0 PL 0,27,198 +17 1102 . T <*> 0 . DP=9;I16=9,0,0,0,356,14128,0,0,540,32400,0,0,192,4452,0,0;QS=1,0;MQ0F=0 PL 0,27,186 +17 1103 . G <*> 0 . DP=10;I16=9,1,0,0,384,14810,0,0,600,36000,0,0,195,4539,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,30,222 +17 1104 . A <*> 0 . DP=10;I16=9,1,0,0,405,16479,0,0,600,36000,0,0,199,4633,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,30,233 +17 1105 . T <*> 0 . DP=10;I16=9,1,0,0,389,15179,0,0,600,36000,0,0,203,4735,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,30,222 +17 1106 . A <*> 0 . DP=10;I16=9,1,0,0,380,14516,0,0,600,36000,0,0,207,4845,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,30,217 +17 1107 . C <*> 0 . DP=10;I16=9,1,0,0,385,14881,0,0,600,36000,0,0,210,4912,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,30,220 +17 1108 . A <*> 0 . DP=10;I16=9,1,0,0,400,16056,0,0,600,36000,0,0,213,4985,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,30,227 +17 1109 . G <*> 0 . DP=10;I16=9,1,0,0,390,15304,0,0,600,36000,0,0,216,5064,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,30,224 +17 1110 . G <*> 0 . DP=10;I16=9,1,0,0,389,15219,0,0,600,36000,0,0,219,5149,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,30,224 +17 1111 . T <*> 0 . DP=10;I16=9,1,0,0,371,13881,0,0,600,36000,0,0,222,5240,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,30,211 +17 1112 . T <*> 0 . DP=10;I16=9,1,0,0,394,15542,0,0,600,36000,0,0,224,5288,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,30,221 +17 1113 . G <*> 0 . DP=11;I16=10,1,0,0,418,15980,0,0,660,39600,0,0,225,5293,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,33,222 +17 1114 . A <*> 0 . DP=11;I16=10,1,0,0,444,18090,0,0,660,39600,0,0,227,5305,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,33,238 +17 1115 . G <*> 0 . DP=11;I16=10,1,0,0,442,17812,0,0,660,39600,0,0,229,5325,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,33,234 +17 1116 . G <*> 0 . DP=11;I16=10,1,0,0,415,15869,0,0,660,39600,0,0,231,5353,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,33,226 +17 1117 . A <*> 0 . DP=11;I16=10,1,0,0,441,17783,0,0,660,39600,0,0,233,5389,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,33,234 +17 1118 . T <*> 0 . DP=12;I16=10,1,0,0,471,21403,0,0,660,39600,0,0,233,5335,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,33,248 +17 1119 . C <*> 0 . DP=12;I16=10,1,0,0,480,22008,0,0,660,39600,0,0,233,5293,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,33,255 +17 1120 . C <*> 0 . DP=12;I16=10,1,0,0,479,22119,0,0,660,39600,0,0,233,5263,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,33,255 +17 1121 . A <*> 0 . DP=13;I16=11,1,0,0,515,23435,0,0,720,43200,0,0,233,5245,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,36,255 +17 1122 . T <*> 0 . DP=13;I16=11,1,0,0,517,23663,0,0,720,43200,0,0,233,5189,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,36,255 +17 1123 . T <*> 0 . DP=13;I16=11,1,0,0,521,24255,0,0,720,43200,0,0,233,5145,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,36,255 +17 1124 . A <*> 0 . DP=13;I16=11,1,0,0,514,23562,0,0,720,43200,0,0,233,5113,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,36,255 +17 1125 . T <*> 0 . DP=13;I16=11,1,0,0,527,24853,0,0,720,43200,0,0,233,5093,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,36,255 +17 1126 . C <*> 0 . DP=13;I16=11,1,0,0,527,24651,0,0,720,43200,0,0,233,5085,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,36,255 +17 1127 . T <*> 0 . DP=13;I16=11,1,0,0,541,26591,0,0,720,43200,0,0,233,5089,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,36,255 +17 1128 . G <*> 0 . DP=13;I16=11,1,0,0,525,24825,0,0,720,43200,0,0,233,5105,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,36,255 +17 1129 . A G,<*> 0 . DP=13;I16=11,0,0,1,482,22610,32,1024,660,39600,60,3600,207,4457,25,625;QS=0.935354,0.0646465,0;SGB=-0.379885;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL 0,4,198,33,201,219 +17 1130 . A <*> 0 . DP=13;I16=11,1,0,0,525,24437,0,0,720,43200,0,0,231,5069,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,36,255 +17 1131 . A <*> 0 . DP=13;I16=11,1,0,0,520,23980,0,0,720,43200,0,0,230,5066,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,36,255 +17 1132 . T <*> 0 . DP=13;I16=11,1,0,0,524,24784,0,0,720,43200,0,0,229,5073,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,36,255 +17 1133 . G <*> 0 . DP=13;I16=11,1,0,0,524,24346,0,0,720,43200,0,0,228,5090,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,36,255 +17 1134 . C <*> 0 . DP=13;I16=11,1,0,0,536,25356,0,0,720,43200,0,0,227,5117,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,36,255 +17 1135 . T <*> 0 . DP=13;I16=11,1,0,0,563,28333,0,0,720,43200,0,0,226,5154,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,36,255 +17 1136 . T <*> 0 . DP=13;I16=11,1,0,0,521,24617,0,0,720,43200,0,0,225,5201,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,36,255 +17 1137 . G <*> 0 . DP=12;I16=10,1,0,0,480,22386,0,0,660,39600,0,0,225,5257,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,33,254 +17 1138 . G <*> 0 . DP=12;I16=10,1,0,0,458,20666,0,0,660,39600,0,0,225,5321,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,33,246 +17 1139 . A <*> 0 . DP=12;I16=10,1,0,0,490,23474,0,0,660,39600,0,0,224,5342,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,33,255 +17 1140 . C <*> 0 . DP=12;I16=10,1,0,0,465,20947,0,0,660,39600,0,0,223,5369,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,33,250 +17 1141 . C <*> 0 . DP=12;I16=10,1,0,0,487,22793,0,0,660,39600,0,0,222,5402,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,33,255 +17 1142 . A <*> 0 . DP=12;I16=10,1,0,0,469,21715,0,0,660,39600,0,0,220,5392,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,33,251 +17 1143 . G <*> 0 . DP=10;I16=8,2,0,0,401,16179,0,0,600,36000,0,0,245,6013,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,30,253 +17 1144 . A <*> 0 . DP=10;I16=8,2,0,0,400,16170,0,0,600,36000,0,0,245,6013,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,30,255 +17 1145 . T <*> 0 . DP=10;I16=8,2,0,0,394,15618,0,0,600,36000,0,0,244,5968,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,30,249 +17 1146 . G <*> 0 . DP=10;I16=8,2,0,0,400,16058,0,0,600,36000,0,0,243,5929,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,30,254 +17 1147 . T <*> 0 . DP=10;I16=8,2,0,0,397,16013,0,0,600,36000,0,0,241,5845,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,30,255 +17 1148 . T <*> 0 . DP=10;I16=8,2,0,0,404,16434,0,0,600,36000,0,0,239,5765,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,30,255 +17 1149 . T <*> 0 . DP=10;I16=8,2,0,0,417,17443,0,0,600,36000,0,0,237,5689,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,30,255 +17 1150 . T <*> 0 . DP=10;I16=8,2,0,0,412,17020,0,0,600,36000,0,0,235,5617,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,30,255 +17 1151 . G <*> 0 . DP=10;I16=8,2,0,0,393,15523,0,0,600,36000,0,0,233,5549,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,30,248 +17 1152 . A <*> 0 . DP=11;I16=8,3,0,0,441,18063,0,0,660,39600,0,0,231,5485,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,33,255 +17 1153 . A <*> 0 . DP=11;I16=8,3,0,0,438,17700,0,0,660,39600,0,0,229,5377,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,33,255 +17 1154 . T <*> 0 . DP=11;I16=8,3,0,0,434,17352,0,0,660,39600,0,0,227,5277,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,33,255 +17 1155 . T <*> 0 . DP=11;I16=8,3,0,0,450,18518,0,0,660,39600,0,0,225,5185,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,33,255 +17 1156 . T <*> 0 . DP=11;I16=8,3,0,0,454,18846,0,0,660,39600,0,0,223,5101,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,33,255 +17 1157 . T <*> 0 . DP=11;I16=8,3,0,0,455,18851,0,0,660,39600,0,0,220,4976,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,33,255 +17 1158 . G <*> 0 . DP=11;I16=8,3,0,0,456,18954,0,0,660,39600,0,0,217,4861,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,33,255 +17 1159 . G <*> 0 . DP=11;I16=8,3,0,0,432,17154,0,0,660,39600,0,0,214,4756,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,33,255 +17 1160 . A <*> 0 . DP=13;I16=8,5,0,0,490,18826,0,0,780,46800,0,0,211,4661,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,39,255 +17 1161 . T <*> 0 . DP=13;I16=8,5,0,0,508,20040,0,0,780,46800,0,0,210,4578,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,39,255 +17 1162 . T <*> 0 . DP=13;I16=8,5,0,0,507,19989,0,0,780,46800,0,0,209,4509,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,39,255 +17 1163 . T <*> 0 . DP=13;I16=8,5,0,0,515,20589,0,0,780,46800,0,0,207,4405,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,39,255 +17 1164 . T <*> 0 . DP=13;I16=8,5,0,0,515,20623,0,0,780,46800,0,0,205,4317,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,39,255 +17 1165 . T <*> 0 . DP=13;I16=8,5,0,0,534,22138,0,0,780,46800,0,0,203,4245,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,39,255 +17 1166 . T <*> 0 . DP=13;I16=8,5,0,0,510,20260,0,0,780,46800,0,0,201,4189,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,39,255 +17 1167 . C <*> 0 . DP=12;I16=7,5,0,0,479,19261,0,0,720,43200,0,0,200,4148,0,0;QS=1,0;MQSB=0.95494;MQ0F=0 PL 0,36,255 +17 1168 . A <*> 0 . DP=12;I16=7,5,0,0,482,19408,0,0,720,43200,0,0,199,4121,0,0;QS=1,0;MQSB=0.95494;MQ0F=0 PL 0,36,255 +17 1169 . T <*> 0 . DP=12;I16=7,5,0,0,473,18741,0,0,720,43200,0,0,198,4108,0,0;QS=1,0;MQSB=0.95494;MQ0F=0 PL 0,36,255 +17 1170 . A <*> 0 . DP=11;I16=6,5,0,0,421,16377,0,0,660,39600,0,0,198,4108,0,0;QS=1,0;MQSB=0.950952;MQ0F=0 PL 0,33,255 +17 1171 . T <*> 0 . DP=11;I16=6,5,0,0,437,17453,0,0,660,39600,0,0,198,4120,0,0;QS=1,0;MQSB=0.950952;MQ0F=0 PL 0,33,255 +17 1172 . T <*> 0 . DP=11;I16=6,5,0,0,451,18549,0,0,660,39600,0,0,197,4095,0,0;QS=1,0;MQSB=0.950952;MQ0F=0 PL 0,33,255 +17 1173 . T <*> 0 . DP=11;I16=6,5,0,0,449,18407,0,0,660,39600,0,0,196,4084,0,0;QS=1,0;MQSB=0.950952;MQ0F=0 PL 0,33,255 +17 1174 . T <*> 0 . DP=11;I16=6,5,0,0,443,17907,0,0,660,39600,0,0,195,4087,0,0;QS=1,0;MQSB=0.950952;MQ0F=0 PL 0,33,255 +17 1175 . G <*> 0 . DP=11;I16=6,5,0,0,411,15559,0,0,660,39600,0,0,194,4104,0,0;QS=1,0;MQSB=0.950952;MQ0F=0 PL 0,33,255 +17 1176 . T <*> 0 . DP=11;I16=6,5,0,0,406,15662,0,0,660,39600,0,0,193,4135,0,0;QS=1,0;MQSB=0.950952;MQ0F=0 PL 0,33,255 +17 1177 . A <*> 0 . DP=11;I16=6,5,0,0,411,15595,0,0,660,39600,0,0,192,4180,0,0;QS=1,0;MQSB=0.950952;MQ0F=0 PL 0,33,255 +17 1178 . A <*> 0 . DP=10;I16=5,5,0,0,387,15163,0,0,600,36000,0,0,191,4187,0,0;QS=1,0;MQSB=0.952347;MQ0F=0 PL 0,30,255 +17 1179 . T <*> 0 . DP=10;I16=5,5,0,0,391,15435,0,0,600,36000,0,0,189,4155,0,0;QS=1,0;MQSB=0.952347;MQ0F=0 PL 0,30,255 +17 1180 . C <*> 0 . DP=10;I16=5,5,0,0,402,16274,0,0,600,36000,0,0,187,4135,0,0;QS=1,0;MQSB=0.952347;MQ0F=0 PL 0,30,255 +17 1181 . T <*> 0 . DP=10;I16=5,5,0,0,395,15843,0,0,600,36000,0,0,185,4127,0,0;QS=1,0;MQSB=0.952347;MQ0F=0 PL 0,30,255 +17 1182 . T <*> 0 . DP=9;I16=4,5,0,0,351,13901,0,0,540,32400,0,0,184,4130,0,0;QS=1,0;MQSB=0.974597;MQ0F=0 PL 0,27,255 +17 1183 . T <*> 0 . DP=9;I16=4,5,0,0,341,13579,0,0,540,32400,0,0,183,4143,0,0;QS=1,0;MQSB=0.974597;MQ0F=0 PL 0,27,255 +17 1184 . G <*> 0 . DP=9;I16=4,5,0,0,354,13996,0,0,540,32400,0,0,182,4166,0,0;QS=1,0;MQSB=0.974597;MQ0F=0 PL 0,27,255 +17 1185 . C <*> 0 . DP=9;I16=4,5,0,0,341,12959,0,0,540,32400,0,0,181,4199,0,0;QS=1,0;MQSB=0.974597;MQ0F=0 PL 0,27,250 +17 1186 . A <*> 0 . DP=9;I16=4,5,0,0,370,15280,0,0,540,32400,0,0,178,4140,0,0;QS=1,0;MQSB=0.974597;MQ0F=0 PL 0,27,255 +17 1187 . G <*> 0 . DP=9;I16=4,5,0,0,320,11816,0,0,540,32400,0,0,175,4087,0,0;QS=1,0;MQSB=0.974597;MQ0F=0 PL 0,27,240 +17 1188 . T <*> 0 . DP=8;I16=3,5,0,0,282,10330,0,0,480,28800,0,0,173,4039,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,216 +17 1189 . A <*> 0 . DP=9;I16=4,5,0,0,342,13108,0,0,540,32400,0,0,170,3946,0,0;QS=1,0;MQSB=0.974597;MQ0F=0 PL 0,27,252 +17 1190 . T <*> 0 . DP=9;I16=4,5,0,0,341,13061,0,0,540,32400,0,0,168,3860,0,0;QS=1,0;MQSB=0.974597;MQ0F=0 PL 0,27,252 +17 1191 . A <*> 0 . DP=9;I16=4,5,0,0,330,12352,0,0,540,32400,0,0,166,3782,0,0;QS=1,0;MQSB=0.974597;MQ0F=0 PL 0,27,245 +17 1192 . T <*> 0 . DP=9;I16=4,5,0,0,346,13400,0,0,540,32400,0,0,164,3712,0,0;QS=1,0;MQSB=0.974597;MQ0F=0 PL 0,27,255 +17 1193 . T <*> 0 . DP=9;I16=4,5,0,0,346,13426,0,0,540,32400,0,0,162,3650,0,0;QS=1,0;MQSB=0.974597;MQ0F=0 PL 0,27,255 +17 1194 . T <*> 0 . DP=9;I16=4,5,0,0,336,12702,0,0,540,32400,0,0,159,3547,0,0;QS=1,0;MQSB=0.974597;MQ0F=0 PL 0,27,249 +17 1195 . A <*> 0 . DP=9;I16=4,5,0,0,313,11337,0,0,540,32400,0,0,156,3454,0,0;QS=1,0;MQSB=0.974597;MQ0F=0 PL 0,27,235 +17 1196 . C <*> 0 . DP=9;I16=4,5,0,0,319,11405,0,0,540,32400,0,0,153,3371,0,0;QS=1,0;MQSB=0.974597;MQ0F=0 PL 0,27,236 +17 1197 . C <*> 0 . DP=8;I16=3,5,0,0,308,11896,0,0,480,28800,0,0,150,3248,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,233 +17 1198 . A <*> 0 . DP=8;I16=3,5,0,0,321,12969,0,0,480,28800,0,0,147,3135,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,245 +17 1199 . G <*> 0 . DP=8;I16=3,5,0,0,290,10626,0,0,480,28800,0,0,144,3032,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,221 +17 1200 . T <*> 0 . DP=8;I16=3,5,0,0,326,13324,0,0,480,28800,0,0,141,2939,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,247 +17 1201 . T <*> 0 . DP=8;I16=3,5,0,0,317,12581,0,0,480,28800,0,0,138,2856,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,238 +17 1202 . C <*> 0 . DP=8;I16=3,5,0,0,305,11673,0,0,480,28800,0,0,135,2783,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,230 +17 1203 . A <*> 0 . DP=8;I16=3,5,0,0,316,12606,0,0,480,28800,0,0,132,2720,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,241 +17 1204 . G <*> 0 . DP=7;I16=3,4,0,0,272,10668,0,0,420,25200,0,0,130,2666,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,218 +17 1205 . C <*> 0 . DP=7;I16=3,4,0,0,271,10615,0,0,420,25200,0,0,128,2620,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,217 +17 1206 . A <*> 0 . DP=7;I16=3,4,0,0,261,10111,0,0,420,25200,0,0,126,2582,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,212 +17 1207 . T <*> 0 . DP=7;I16=3,3,0,0,232,9016,0,0,360,21600,0,0,99,1927,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,194 +17 1208 . C <*> 0 . DP=7;I16=3,4,0,0,271,10567,0,0,420,25200,0,0,122,2530,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,217 +17 1209 . C <*> 0 . DP=7;I16=3,4,0,0,260,9798,0,0,420,25200,0,0,120,2516,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,209 +17 1210 . C <*> 0 . DP=7;I16=3,4,0,0,258,9874,0,0,420,25200,0,0,118,2510,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,209 +17 1211 . T <*> 0 . DP=7;I16=3,4,0,0,264,10200,0,0,420,25200,0,0,116,2512,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,214 +17 1212 . A <*> 0 . DP=7;I16=3,4,0,0,256,9428,0,0,420,25200,0,0,114,2522,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,204 +17 1213 . A <*> 0 . DP=7;I16=3,4,0,0,238,8688,0,0,420,25200,0,0,112,2540,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,195 +17 1214 . C <*> 0 . DP=6;I16=2,4,0,0,223,8441,0,0,360,21600,0,0,111,2565,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,184 +17 1215 . T <*> 0 . DP=6;I16=2,3,0,0,198,7884,0,0,300,18000,0,0,84,1920,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,172 +17 1216 . C <*> 0 . DP=6;I16=2,4,0,0,207,7455,0,0,360,21600,0,0,107,2529,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,172 +17 1217 . A <*> 0 . DP=6;I16=2,4,0,0,231,9037,0,0,360,21600,0,0,105,2517,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,191 +17 1218 . A <*> 0 . DP=6;I16=2,4,0,0,223,8501,0,0,360,21600,0,0,103,2509,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,184 +17 1219 . A <*> 0 . DP=5;I16=2,3,0,0,199,8003,0,0,300,18000,0,0,102,2504,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,173 +17 1220 . A <*> 0 . DP=5;I16=2,3,0,0,191,7451,0,0,300,18000,0,0,101,2501,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,167 +17 1221 . A <*> 0 . DP=5;I16=2,3,0,0,179,6643,0,0,300,18000,0,0,100,2500,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,157 +17 1222 . T <*> 0 . DP=4;I16=1,3,0,0,161,6531,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,142 +17 1223 . T <*> 0 . DP=4;I16=1,2,0,0,127,5379,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,120 +17 1224 . C <*> 0 . DP=4;I16=1,2,0,0,119,4723,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,112 +17 1225 . A <*> 0 . DP=4;I16=1,3,0,0,165,6809,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,145 +17 1226 . A <*> 0 . DP=4;I16=1,3,0,0,168,7058,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,147 +17 1227 . A <*> 0 . DP=4;I16=1,3,0,0,167,6977,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,146 +17 1228 . A <*> 0 . DP=4;I16=1,3,0,0,166,6894,0,0,240,14400,0,0,99,2451,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,145 +17 1229 . A <*> 0 . DP=4;I16=1,3,0,0,157,6219,0,0,240,14400,0,0,98,2404,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,138 +17 1230 . T <*> 0 . DP=4;I16=1,3,0,0,164,6734,0,0,240,14400,0,0,97,2359,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,144 +17 1231 . C <*> 0 . DP=4;I16=1,3,0,0,157,6235,0,0,240,14400,0,0,96,2316,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,138 +17 1232 . T <*> 0 . DP=4;I16=1,3,0,0,145,5431,0,0,240,14400,0,0,95,2275,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,129 +17 1233 . G <*> 0 . DP=4;I16=1,3,0,0,144,5422,0,0,240,14400,0,0,94,2236,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,129 +17 1234 . A <*> 0 . DP=4;I16=1,3,0,0,164,6736,0,0,240,14400,0,0,93,2199,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,144 +17 1235 . A <*> 0 . DP=4;I16=1,3,0,0,159,6367,0,0,240,14400,0,0,92,2164,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,140 +17 1236 . A <*> 0 . DP=4;I16=1,3,0,0,153,5977,0,0,240,14400,0,0,89,2033,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,136 +17 1237 . T <*> 0 . DP=4;I16=1,3,0,0,152,5912,0,0,240,14400,0,0,86,1908,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,135 +17 1238 . C <*> 0 . DP=4;I16=1,3,0,0,164,6758,0,0,240,14400,0,0,83,1789,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,145 +17 1239 . C <*> 0 . DP=4;I16=1,3,0,0,138,5114,0,0,240,14400,0,0,80,1676,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,124 +17 1240 . C <*> 0 . DP=4;I16=1,3,0,0,145,5407,0,0,240,14400,0,0,77,1569,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,129 +17 1241 . A <*> 0 . DP=4;I16=1,3,0,0,160,6404,0,0,240,14400,0,0,74,1468,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,141 +17 1242 . A <*> 0 . DP=5;I16=2,3,0,0,174,6374,0,0,300,18000,0,0,71,1373,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,153 +17 1243 . A <*> 0 . DP=5;I16=2,3,0,0,181,6649,0,0,300,18000,0,0,69,1285,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,158 +17 1244 . C <*> 0 . DP=5;I16=2,3,0,0,170,5836,0,0,300,18000,0,0,67,1205,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,148 +17 1245 . G <*> 0 . DP=5;I16=2,3,0,0,182,6762,0,0,300,18000,0,0,65,1133,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,158 +17 1246 . C <*> 0 . DP=5;I16=2,3,0,0,168,5688,0,0,300,18000,0,0,63,1069,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,146 +17 1247 . G <*> 0 . DP=5;I16=2,3,0,0,172,6070,0,0,300,18000,0,0,61,1013,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,150 +17 1248 . C <*> 0 . DP=5;I16=2,3,0,0,179,6455,0,0,300,18000,0,0,59,965,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,156 +17 1249 . C <*> 0 . DP=5;I16=2,3,0,0,192,7386,0,0,300,18000,0,0,57,925,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,166 +17 1250 . A <*> 0 . DP=5;I16=2,3,0,0,186,6930,0,0,300,18000,0,0,55,893,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,161 +17 1251 . A <*> 0 . DP=5;I16=2,3,0,0,200,8038,0,0,300,18000,0,0,53,869,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,174 +17 1252 . T <*> 0 . DP=5;I16=2,3,0,0,183,6753,0,0,300,18000,0,0,51,853,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,159 +17 1253 . A <*> 0 . DP=4;I16=2,2,0,0,158,6242,0,0,240,14400,0,0,50,844,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,144 +17 1254 . A <*> 0 . DP=4;I16=2,2,0,0,171,7311,0,0,240,14400,0,0,49,841,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,156 +17 1255 . G <*> 0 . DP=5;I16=2,3,0,0,195,7623,0,0,300,18000,0,0,48,844,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,169 +17 1256 . C <*> 0 . DP=5;I16=2,3,0,0,191,7317,0,0,300,18000,0,0,48,854,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,165 +17 1257 . A <*> 0 . DP=5;I16=2,3,0,0,193,7457,0,0,300,18000,0,0,48,872,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,167 +17 1258 . T <*> 0 . DP=5;I16=2,3,0,0,196,7692,0,0,300,18000,0,0,48,898,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,170 +17 1259 . T <*> 0 . DP=5;I16=2,3,0,0,197,7765,0,0,300,18000,0,0,48,932,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,170 +17 1260 . C <*> 0 . DP=5;I16=2,3,0,0,177,6415,0,0,300,18000,0,0,48,974,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,155 +17 1261 . C <*> 0 . DP=3;I16=2,1,0,0,116,4502,0,0,180,10800,0,0,50,1022,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,109 +17 1262 . C <*> 0 . DP=3;I16=2,1,0,0,121,4893,0,0,180,10800,0,0,52,1074,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,114 +17 1263 . T <*> 0 . DP=3;I16=2,1,0,0,125,5219,0,0,180,10800,0,0,54,1130,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,118 +17 1264 . T <*> 0 . DP=3;I16=2,1,0,0,121,4883,0,0,180,10800,0,0,56,1190,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,114 +17 1265 . T <*> 0 . DP=3;I16=2,1,0,0,121,4889,0,0,180,10800,0,0,57,1205,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,114 +17 1266 . G <*> 0 . DP=3;I16=2,1,0,0,121,4885,0,0,180,10800,0,0,58,1226,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,114 +17 1267 . A <*> 0 . DP=3;I16=2,1,0,0,120,4878,0,0,180,10800,0,0,59,1253,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,114 +17 1268 . G <*> 0 . DP=3;I16=2,1,0,0,114,4358,0,0,180,10800,0,0,59,1235,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,108 +17 1269 . C <*> 0 . DP=3;I16=2,1,0,0,113,4309,0,0,180,10800,0,0,59,1221,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,107 +17 1270 . G <*> 0 . DP=3;I16=2,1,0,0,104,3624,0,0,180,10800,0,0,59,1211,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,98 +17 1271 . T <*> 0 . DP=3;I16=2,1,0,0,116,4504,0,0,180,10800,0,0,59,1205,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,109 +17 1272 . C <*> 0 . DP=3;I16=2,1,0,0,117,4577,0,0,180,10800,0,0,59,1203,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,110 +17 1273 . A <*> 0 . DP=3;I16=2,1,0,0,120,4806,0,0,180,10800,0,0,59,1205,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,113 +17 1274 . T <*> 0 . DP=3;I16=2,1,0,0,122,4962,0,0,180,10800,0,0,59,1211,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,115 +17 1275 . G <*> 0 . DP=3;I16=2,1,0,0,119,4725,0,0,180,10800,0,0,59,1221,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,112 +17 1276 . T <*> 0 . DP=3;I16=2,1,0,0,117,4581,0,0,180,10800,0,0,59,1235,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,110 +17 1277 . C <*> 0 . DP=3;I16=2,1,0,0,113,4305,0,0,180,10800,0,0,59,1253,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,106 +17 1278 . G <*> 0 . DP=3;I16=2,1,0,0,102,3524,0,0,180,10800,0,0,59,1275,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,96 +17 1279 . G <*> 0 . DP=3;I16=2,1,0,0,120,4806,0,0,180,10800,0,0,59,1301,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,113 +17 1280 . T <*> 0 . DP=3;I16=2,1,0,0,103,3581,0,0,180,10800,0,0,59,1331,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,97 +17 1281 . G <*> 0 . DP=3;I16=2,1,0,0,109,4009,0,0,180,10800,0,0,58,1314,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,103 +17 1282 . C <*> 0 . DP=4;I16=2,2,0,0,143,5185,0,0,240,14400,0,0,57,1299,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,131 +17 1283 . T <*> 0 . DP=4;I16=2,2,0,0,168,7104,0,0,240,14400,0,0,57,1287,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,154 +17 1284 . T <*> 0 . DP=4;I16=2,2,0,0,159,6341,0,0,240,14400,0,0,57,1279,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,145 +17 1285 . G <*> 0 . DP=4;I16=2,2,0,0,159,6327,0,0,240,14400,0,0,57,1275,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,145 +17 1286 . G <*> 0 . DP=4;I16=2,2,0,0,161,6525,0,0,240,14400,0,0,57,1275,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,148 +17 1287 . A <*> 0 . DP=4;I16=2,2,0,0,149,5605,0,0,240,14400,0,0,57,1279,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,137 +17 1288 . A <*> 0 . DP=4;I16=2,2,0,0,153,5895,0,0,240,14400,0,0,57,1287,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,140 +17 1289 . T <*> 0 . DP=4;I16=2,2,0,0,154,5970,0,0,240,14400,0,0,57,1299,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,141 +17 1290 . G <*> 0 . DP=3;I16=1,2,0,0,112,4242,0,0,180,10800,0,0,58,1314,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,106 +17 1291 . T <*> 0 . DP=3;I16=1,2,0,0,124,5146,0,0,180,10800,0,0,59,1331,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,117 +17 1292 . T <*> 0 . DP=3;I16=1,2,0,0,119,4773,0,0,180,10800,0,0,60,1350,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,113 +17 1293 . T <*> 0 . DP=3;I16=1,2,0,0,124,5126,0,0,180,10800,0,0,61,1371,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,116 +17 1294 . G <*> 0 . DP=3;I16=1,2,0,0,126,5306,0,0,180,10800,0,0,62,1394,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,119 +17 1295 . G <*> 0 . DP=3;I16=1,2,0,0,121,4913,0,0,180,10800,0,0,63,1419,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,114 +17 1296 . G <*> 0 . DP=3;I16=1,2,0,0,121,4899,0,0,180,10800,0,0,64,1446,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,114 +17 1297 . G <*> 0 . DP=4;I16=1,3,0,0,151,5765,0,0,240,14400,0,0,65,1475,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,133 +17 1298 . T <*> 0 . DP=4;I16=1,3,0,0,157,6219,0,0,240,14400,0,0,67,1507,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,138 +17 1299 . T <*> 0 . DP=4;I16=1,3,0,0,154,5998,0,0,240,14400,0,0,69,1543,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,136 +17 1300 . T <*> 0 . DP=4;I16=1,3,0,0,153,5915,0,0,240,14400,0,0,71,1583,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,136 +17 1301 . T <*> 0 . DP=4;I16=1,3,0,0,153,5885,0,0,240,14400,0,0,73,1627,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,135 +17 1302 . G <*> 0 . DP=4;I16=1,3,0,0,158,6268,0,0,240,14400,0,0,75,1675,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,140 +17 1303 . G <*> 0 . DP=4;I16=1,3,0,0,156,6126,0,0,240,14400,0,0,77,1727,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,138 +17 1304 . A <*> 0 . DP=5;I16=2,3,0,0,194,7576,0,0,300,18000,0,0,79,1783,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,169 +17 1305 . T <*> 0 . DP=5;I16=2,3,0,0,199,7959,0,0,300,18000,0,0,82,1844,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,174 +17 1306 . T <*> 0 . DP=5;I16=2,3,0,0,192,7426,0,0,300,18000,0,0,85,1911,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,168 +17 1307 . T <*> 0 . DP=5;I16=2,3,0,0,192,7402,0,0,300,18000,0,0,88,1984,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,167 +17 1308 . A <*> 0 . DP=5;I16=2,3,0,0,198,7848,0,0,300,18000,0,0,90,2012,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,173 +17 1309 . C <*> 0 . DP=5;I16=2,3,0,0,194,7562,0,0,300,18000,0,0,92,2044,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,169 +17 1310 . A <*> 0 . DP=5;I16=2,3,0,0,210,8856,0,0,300,18000,0,0,94,2080,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,183 +17 1311 . G <*> 0 . DP=5;I16=2,3,0,0,200,8026,0,0,300,18000,0,0,96,2120,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,174 +17 1312 . C <*> 0 . DP=5;I16=2,3,0,0,190,7340,0,0,300,18000,0,0,98,2164,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,166 +17 1313 . T <*> 0 . DP=5;I16=2,3,0,0,201,8159,0,0,300,18000,0,0,100,2212,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,175 +17 1314 . T <*> 0 . DP=5;I16=2,3,0,0,199,7973,0,0,300,18000,0,0,102,2264,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,174 +17 1315 . T <*> 0 . DP=5;I16=2,3,0,0,200,8022,0,0,300,18000,0,0,104,2320,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,174 +17 1316 . G <*> 0 . DP=6;I16=2,4,0,0,229,8827,0,0,360,21600,0,0,106,2380,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,188 +17 1317 . G <*> 0 . DP=6;I16=2,4,0,0,220,8092,0,0,360,21600,0,0,109,2445,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,179 +17 1318 . G <*> 0 . DP=6;I16=2,4,0,0,227,8609,0,0,360,21600,0,0,111,2467,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,184 +17 1319 . A <*> 0 . DP=6;I16=2,4,0,0,229,8767,0,0,360,21600,0,0,113,2497,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,186 +17 1320 . C <*> 0 . DP=6;I16=2,4,0,0,198,6562,0,0,360,21600,0,0,115,2535,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,161 +17 1321 . G <*> 0 . DP=8;I16=2,6,0,0,288,10604,0,0,480,28800,0,0,117,2581,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,208 +17 1322 . C <*> 0 . DP=8;I16=2,6,0,0,313,12275,0,0,480,28800,0,0,121,2637,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,225 +17 1323 . T <*> 0 . DP=8;I16=2,6,0,0,333,13883,0,0,480,28800,0,0,124,2654,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,237 +17 1324 . C <*> 0 . DP=8;I16=2,6,0,0,306,11730,0,0,480,28800,0,0,127,2681,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,218 +17 1325 . A <*> 0 . DP=8;I16=2,6,0,0,304,11616,0,0,480,28800,0,0,130,2718,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,218 +17 1326 . A <*> 0 . DP=8;I16=2,6,0,0,320,12836,0,0,480,28800,0,0,133,2765,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,230 +17 1327 . C <*> 0 . DP=9;I16=3,6,0,0,331,12449,0,0,540,32400,0,0,136,2822,0,0;QS=1,0;MQSB=0.924584;MQ0F=0 PL 0,27,237 +17 1328 . C <*> 0 . DP=9;I16=3,6,0,0,354,14090,0,0,540,32400,0,0,140,2890,0,0;QS=1,0;MQSB=0.924584;MQ0F=0 PL 0,27,254 +17 1329 . T <*> 0 . DP=9;I16=3,6,0,0,363,14827,0,0,540,32400,0,0,144,2970,0,0;QS=1,0;MQSB=0.924584;MQ0F=0 PL 0,27,255 +17 1330 . G <*> 0 . DP=9;I16=3,6,0,0,337,12805,0,0,540,32400,0,0,147,3011,0,0;QS=1,0;MQSB=0.924584;MQ0F=0 PL 0,27,241 +17 1331 . T <*> 0 . DP=9;I16=3,6,0,0,345,13287,0,0,540,32400,0,0,149,3013,0,0;QS=1,0;MQSB=0.924584;MQ0F=0 PL 0,27,247 +17 1332 . A <*> 0 . DP=9;I16=3,6,0,0,335,12679,0,0,540,32400,0,0,151,3027,0,0;QS=1,0;MQSB=0.924584;MQ0F=0 PL 0,27,238 +17 1333 . C <*> 0 . DP=9;I16=3,6,0,0,327,12185,0,0,540,32400,0,0,153,3053,0,0;QS=1,0;MQSB=0.924584;MQ0F=0 PL 0,27,236 +17 1334 . C <*> 0 . DP=9;I16=3,6,0,0,332,12928,0,0,540,32400,0,0,155,3091,0,0;QS=1,0;MQSB=0.924584;MQ0F=0 PL 0,27,238 +17 1335 . T <*> 0 . DP=9;I16=3,6,0,0,352,14130,0,0,540,32400,0,0,157,3141,0,0;QS=1,0;MQSB=0.924584;MQ0F=0 PL 0,27,253 +17 1336 . C <*> 0 . DP=10;I16=2,7,0,0,353,13889,0,0,540,32400,0,0,150,3122,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,27,237 +17 1337 . A <*> 0 . DP=10;I16=3,7,0,0,363,13487,0,0,600,36000,0,0,162,3278,0,0;QS=1,0;MQSB=0.916482;MQ0F=0 PL 0,30,247 +17 1338 . A <*> 0 . DP=10;I16=3,7,0,0,395,15639,0,0,600,36000,0,0,165,3367,0,0;QS=1,0;MQSB=0.916482;MQ0F=0 PL 0,30,255 +17 1339 . T <*> 0 . DP=11;I16=3,8,0,0,408,15356,0,0,660,39600,0,0,168,3470,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,33,255 +17 1340 . A <*> 0 . DP=11;I16=3,8,0,0,398,14576,0,0,660,39600,0,0,172,3588,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,33,254 +17 1341 . A <*> 0 . DP=11;I16=3,8,0,0,398,14636,0,0,660,39600,0,0,176,3722,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,33,255 +17 1342 . A <*> 0 . DP=11;I16=3,8,0,0,381,13615,0,0,660,39600,0,0,179,3821,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,33,249 +17 1343 . C <*> 0 . DP=10;I16=2,8,0,0,369,13821,0,0,600,36000,0,0,183,3933,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,30,233 +17 1344 . C <*> 0 . DP=10;I16=2,8,0,0,377,14509,0,0,600,36000,0,0,187,4057,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,30,238 +17 1345 . T <*> 0 . DP=10;I16=2,8,0,0,386,15194,0,0,600,36000,0,0,191,4193,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,30,242 +17 1346 . G <*> 0 . DP=10;I16=2,8,0,0,380,14626,0,0,600,36000,0,0,195,4341,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,30,239 +17 1347 . A <*> 0 . DP=10;I16=2,8,0,0,388,15314,0,0,600,36000,0,0,197,4399,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,30,243 +17 1348 . T <*> 0 . DP=10;I16=2,8,0,0,395,15653,0,0,600,36000,0,0,199,4465,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,30,251 +17 1349 . T <*> 0 . DP=10;I16=2,8,0,0,389,15189,0,0,600,36000,0,0,201,4539,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,30,248 +17 1350 . T <*> 0 . DP=10;I16=2,8,0,0,392,15402,0,0,600,36000,0,0,203,4621,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,30,249 +17 1351 . T <*> 0 . DP=10;I16=2,8,0,0,384,14782,0,0,600,36000,0,0,205,4711,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,30,240 +17 1352 . A <*> 0 . DP=10;I16=2,8,0,0,326,10954,0,0,600,36000,0,0,207,4809,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,30,211 +17 1353 . A <*> 0 . DP=10;I16=2,8,0,0,349,12427,0,0,600,36000,0,0,208,4864,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,30,224 +17 1354 . A <*> 0 . DP=10;I16=2,8,0,0,347,12377,0,0,600,36000,0,0,209,4925,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,30,223 +17 1355 . A <*> 0 . DP=10;I16=2,8,0,0,350,12570,0,0,600,36000,0,0,210,4992,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,30,227 +17 1356 . A <*> 0 . DP=9;I16=2,7,0,0,335,12575,0,0,540,32400,0,0,212,5064,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,27,226 +17 1357 . A <*> 0 . DP=9;I16=1,7,0,0,334,13954,0,0,480,28800,0,0,189,4515,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,217 +17 1358 . G <*> 0 . DP=9;I16=1,7,0,0,287,10393,0,0,480,28800,0,0,190,4546,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,188 +17 1359 . T <*> 0 . DP=9;I16=1,7,0,0,302,11428,0,0,480,28800,0,0,191,4583,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,196 +17 1360 . T <*> 0 . DP=9;I16=1,7,0,0,290,10640,0,0,480,28800,0,0,192,4626,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,192 +17 1361 . T <*> 0 . DP=10;I16=1,8,0,0,343,13095,0,0,540,32400,0,0,193,4675,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,27,206 +17 1362 . G <*> 0 . DP=9;I16=1,8,0,0,340,12906,0,0,540,32400,0,0,194,4680,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,27,207 +17 1363 . G <*> 0 . DP=9;I16=1,8,0,0,335,12505,0,0,540,32400,0,0,195,4691,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,27,202 +17 1364 . G <*> 0 . DP=9;I16=1,8,0,0,331,12219,0,0,540,32400,0,0,196,4708,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,27,200 +17 1365 . G <*> 0 . DP=9;I16=1,8,0,0,336,12570,0,0,540,32400,0,0,196,4680,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,27,202 +17 1366 . G <*> 0 . DP=9;I16=1,8,0,0,332,12268,0,0,540,32400,0,0,196,4656,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,27,199 +17 1367 . G C,<*> 0 . DP=9;I16=1,7,0,1,296,10982,27,729,480,28800,60,3600,181,4411,15,225;QS=0.916409,0.0835913,0;SGB=-0.379885;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL 0,0,171,24,174,189 +17 1368 . A <*> 0 . DP=9;I16=1,8,0,0,320,11562,0,0,540,32400,0,0,196,4620,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,27,197 +17 1369 . T <*> 0 . DP=9;I16=1,8,0,0,309,10987,0,0,540,32400,0,0,196,4608,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,27,194 +17 1370 . T <*> 0 . DP=10;I16=1,8,0,0,347,13421,0,0,540,32400,0,0,171,3975,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,27,215 +17 1371 . C <*> 0 . DP=10;I16=1,9,0,0,338,11742,0,0,600,36000,0,0,197,4597,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,30,196 +17 1372 . C <*> 0 . DP=10;I16=1,9,0,0,343,12099,0,0,600,36000,0,0,198,4600,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,30,200 +17 1373 . C <*> 0 . DP=10;I16=1,9,0,0,332,11388,0,0,600,36000,0,0,198,4560,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,30,195 +17 1374 . C <*> 0 . DP=10;I16=1,9,0,0,374,14014,0,0,600,36000,0,0,198,4528,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,30,211 +17 1375 . T <*> 0 . DP=10;I16=1,9,0,0,378,14378,0,0,600,36000,0,0,198,4504,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,30,215 +17 1376 . A <*> 0 . DP=10;I16=1,9,0,0,336,11508,0,0,600,36000,0,0,198,4488,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,30,195 +17 1377 . A <*> 0 . DP=10;I16=1,9,0,0,390,15374,0,0,600,36000,0,0,198,4480,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,30,228 +17 1378 . G <*> 0 . DP=10;I16=1,9,0,0,336,11730,0,0,600,36000,0,0,198,4480,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,30,197 +17 1379 . C <*> 0 . DP=10;I16=1,9,0,0,326,11052,0,0,600,36000,0,0,198,4488,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,30,193 +17 1380 . C <*> 0 . DP=10;I16=1,9,0,0,359,13121,0,0,600,36000,0,0,197,4455,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,30,209 +17 1381 . C <*> 0 . DP=12;I16=2,10,0,0,367,11465,0,0,720,43200,0,0,196,4432,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,36,208 +17 1382 . G <*> 0 . DP=12;I16=2,10,0,0,425,15501,0,0,720,43200,0,0,197,4421,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,36,243 +17 1383 . C <*> 0 . DP=11;I16=2,9,0,0,398,14630,0,0,660,39600,0,0,199,4423,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,33,241 +17 1384 . C <*> 0 . DP=11;I16=2,9,0,0,392,14362,0,0,660,39600,0,0,201,4437,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,33,239 +17 1385 . A <*> 0 . DP=11;I16=2,8,0,0,369,13727,0,0,600,36000,0,0,179,3887,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,30,234 +17 1386 . C <*> 0 . DP=11;I16=2,9,0,0,426,16550,0,0,660,39600,0,0,205,4501,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,33,255 +17 1387 . C <*> 0 . DP=11;I16=2,9,0,0,424,16430,0,0,660,39600,0,0,206,4500,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,33,252 +17 1388 . C <*> 0 . DP=11;I16=2,9,0,0,355,11631,0,0,660,39600,0,0,207,4509,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,33,211 +17 1389 . G <*> 0 . DP=11;I16=2,9,0,0,423,16499,0,0,660,39600,0,0,208,4528,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,33,255 +17 1390 . G <*> 0 . DP=11;I16=2,9,0,0,441,17739,0,0,660,39600,0,0,209,4557,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,33,255 +17 1391 . A <*> 0 . DP=11;I16=2,9,0,0,467,19893,0,0,660,39600,0,0,210,4596,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,33,255 +17 1392 . G <*> 0 . DP=11;I16=2,9,0,0,436,17388,0,0,660,39600,0,0,210,4596,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,33,255 +17 1393 . A <*> 0 . DP=11;I16=2,9,0,0,440,17638,0,0,660,39600,0,0,210,4608,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,33,255 +17 1394 . C <*> 0 . DP=11;I16=2,9,0,0,427,16619,0,0,660,39600,0,0,210,4632,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,33,255 +17 1395 . A <*> 0 . DP=11;I16=2,9,0,0,471,20195,0,0,660,39600,0,0,210,4668,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,33,255 +17 1396 . G <*> 0 . DP=11;I16=2,9,0,0,448,18282,0,0,660,39600,0,0,209,4665,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,33,255 +17 1397 . C <*> 0 . DP=11;I16=2,9,0,0,370,12542,0,0,660,39600,0,0,206,4574,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,33,217 +17 1398 . G <*> 0 . DP=10;I16=2,8,0,0,385,15223,0,0,600,36000,0,0,204,4496,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,30,244 +17 1399 . G <*> 0 . DP=10;I16=2,8,0,0,406,16532,0,0,600,36000,0,0,202,4430,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,30,255 +17 1400 . A <*> 0 . DP=10;I16=2,8,0,0,388,15094,0,0,600,36000,0,0,200,4376,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,30,246 +17 1401 . T <*> 0 . DP=10;I16=2,8,0,0,421,17817,0,0,600,36000,0,0,198,4334,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,30,255 +17 1402 . T <*> 0 . DP=10;I16=2,8,0,0,411,16995,0,0,600,36000,0,0,196,4304,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,30,255 +17 1403 . T <*> 0 . DP=10;I16=2,8,0,0,408,16730,0,0,600,36000,0,0,194,4286,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,30,255 +17 1404 . C <*> 0 . DP=10;I16=2,8,0,0,378,14516,0,0,600,36000,0,0,192,4280,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,30,244 +17 1405 . C <*> 0 . DP=9;I16=1,8,0,0,368,15080,0,0,540,32400,0,0,191,4285,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,27,229 +17 1406 . T <*> 0 . DP=9;I16=1,8,0,0,360,14574,0,0,540,32400,0,0,190,4300,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,27,223 +17 1407 . T <*> 0 . DP=9;I16=1,8,0,0,352,13838,0,0,540,32400,0,0,187,4223,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,27,215 +17 1408 . A <*> 0 . DP=9;I16=1,8,0,0,381,16169,0,0,540,32400,0,0,184,4152,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,27,234 +17 1409 . G <*> 0 . DP=9;I16=1,8,0,0,336,12600,0,0,540,32400,0,0,181,4087,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,27,204 +17 1410 . T <*> 0 . DP=9;I16=1,8,0,0,353,13961,0,0,540,32400,0,0,178,4028,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,27,218 +17 1411 . T <*> 0 . DP=9;I16=1,8,0,0,312,11048,0,0,540,32400,0,0,175,3975,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,27,194 +17 1412 . A <*> 0 . DP=9;I16=1,8,0,0,305,10647,0,0,540,32400,0,0,171,3879,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,27,192 +17 1413 . C <*> 0 . DP=9;I16=1,8,0,0,338,12864,0,0,540,32400,0,0,167,3791,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,27,209 +17 1414 . T <*> 0 . DP=9;I16=1,8,0,0,354,14134,0,0,540,32400,0,0,163,3711,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,27,221 +17 1415 . T <*> 0 . DP=9;I16=1,8,0,0,339,12861,0,0,540,32400,0,0,158,3590,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,27,208 +17 1416 . A <*> 0 . DP=9;I16=1,8,0,0,321,11655,0,0,540,32400,0,0,153,3479,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,27,199 +17 1417 . C <*> 0 . DP=8;I16=1,7,0,0,322,13014,0,0,480,28800,0,0,149,3377,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,211 +17 1418 . T <*> 0 . DP=8;I16=1,7,0,0,315,12475,0,0,480,28800,0,0,145,3283,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,207 +17 1419 . A <*> 0 . DP=8;I16=1,7,0,0,298,11188,0,0,480,28800,0,0,141,3197,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,199 +17 1420 . T <*> 0 . DP=8;I16=1,7,0,0,278,9894,0,0,480,28800,0,0,137,3119,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,185 +17 1421 . G <*> 0 . DP=8;I16=1,7,0,0,289,10571,0,0,480,28800,0,0,133,3049,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,191 +17 1422 . C <*> 0 . DP=6;I16=1,5,0,0,238,9522,0,0,360,21600,0,0,131,2985,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,180 +17 1423 . T <*> 0 . DP=6;I16=1,5,0,0,242,9796,0,0,360,21600,0,0,129,2925,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,183 +17 1424 . C <*> 0 . DP=6;I16=1,5,0,0,224,8628,0,0,360,21600,0,0,127,2869,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,174 +17 1425 . C <*> 0 . DP=6;I16=1,5,0,0,235,9297,0,0,360,21600,0,0,125,2817,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,180 +17 1426 . T <*> 0 . DP=6;I16=1,5,0,0,248,10316,0,0,360,21600,0,0,123,2769,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,188 +17 1427 . T <*> 0 . DP=6;I16=1,5,0,0,231,8983,0,0,360,21600,0,0,121,2725,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,176 +17 1428 . G <*> 0 . DP=6;I16=1,5,0,0,215,8003,0,0,360,21600,0,0,119,2685,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,166 +17 1429 . G <*> 0 . DP=6;I16=1,5,0,0,193,6817,0,0,360,21600,0,0,117,2649,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,148 +17 1430 . C <*> 0 . DP=6;I16=1,5,0,0,203,7173,0,0,360,21600,0,0,115,2617,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,157 +17 1431 . C <*> 0 . DP=6;I16=1,5,0,0,218,8024,0,0,360,21600,0,0,113,2589,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,167 +17 1432 . A <*> 0 . DP=6;I16=1,5,0,0,221,8225,0,0,360,21600,0,0,111,2565,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,169 +17 1433 . T <*> 0 . DP=6;I16=1,5,0,0,230,8890,0,0,360,21600,0,0,109,2545,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,174 +17 1434 . T <*> 0 . DP=6;I16=1,5,0,0,236,9342,0,0,360,21600,0,0,107,2529,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,179 +17 1435 . T <*> 0 . DP=6;I16=1,5,0,0,235,9247,0,0,360,21600,0,0,105,2517,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,180 +17 1436 . C <*> 0 . DP=6;I16=1,5,0,0,215,7865,0,0,360,21600,0,0,103,2509,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,165 +17 1437 . T <*> 0 . DP=5;I16=1,4,0,0,197,7827,0,0,300,18000,0,0,101,2455,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,161 +17 1438 . C <*> 0 . DP=5;I16=1,4,0,0,193,7559,0,0,300,18000,0,0,99,2405,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,159 +17 1439 . T <*> 0 . DP=5;I16=1,4,0,0,190,7308,0,0,300,18000,0,0,97,2359,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,156 +17 1440 . A <*> 0 . DP=4;I16=1,3,0,0,164,6732,0,0,240,14400,0,0,96,2316,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,144 +17 1441 . G <*> 0 . DP=4;I16=1,3,0,0,155,6061,0,0,240,14400,0,0,95,2275,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,137 +17 1442 . G <*> 0 . DP=4;I16=1,3,0,0,145,5303,0,0,240,14400,0,0,94,2236,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,128 +17 1443 . T <*> 0 . DP=4;I16=1,3,0,0,151,5715,0,0,240,14400,0,0,93,2199,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,133 +17 1444 . A <*> 0 . DP=4;I16=1,3,0,0,150,5630,0,0,240,14400,0,0,92,2164,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,132 +17 1445 . T <*> 0 . DP=5;I16=2,3,0,0,194,7650,0,0,300,18000,0,0,91,2131,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,169 +17 1446 . T <*> 0 . DP=5;I16=2,3,0,0,189,7203,0,0,300,18000,0,0,90,2052,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,164 +17 1447 . G <*> 0 . DP=5;I16=2,3,0,0,179,6671,0,0,300,18000,0,0,89,1979,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,157 +17 1448 . G <*> 0 . DP=5;I16=2,3,0,0,171,6007,0,0,300,18000,0,0,88,1912,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,150 +17 1449 . T <*> 0 . DP=5;I16=2,3,0,0,174,6280,0,0,300,18000,0,0,87,1851,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,152 +17 1450 . A <*> 0 . DP=5;I16=2,3,0,0,190,7256,0,0,300,18000,0,0,86,1796,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,165 +17 1451 . T <*> 0 . DP=5;I16=2,3,0,0,181,6669,0,0,300,18000,0,0,85,1747,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,158 +17 1452 . A <*> 0 . DP=5;I16=2,3,0,0,168,5912,0,0,300,18000,0,0,84,1704,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,147 +17 1453 . T <*> 0 . DP=5;I16=2,3,0,0,189,7229,0,0,300,18000,0,0,83,1667,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,165 +17 1454 . T <*> 0 . DP=5;I16=2,3,0,0,191,7335,0,0,300,18000,0,0,82,1636,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,166 +17 1455 . G <*> 0 . DP=5;I16=2,3,0,0,168,5932,0,0,300,18000,0,0,81,1611,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,148 +17 1456 . T <*> 0 . DP=5;I16=2,3,0,0,197,7771,0,0,300,18000,0,0,80,1592,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,170 +17 1457 . G <*> 0 . DP=5;I16=2,3,0,0,189,7193,0,0,300,18000,0,0,77,1481,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,164 +17 1458 . T <*> 0 . DP=5;I16=2,3,0,0,190,7292,0,0,300,18000,0,0,74,1380,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,165 +17 1459 . C A,<*> 0 . DP=5;I16=2,2,0,1,164,6734,24,576,240,14400,60,3600,69,1285,2,4;QS=0.87234,0.12766,0;SGB=-0.379885;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL 9,0,135,21,138,152 +17 1460 . T <*> 0 . DP=5;I16=2,3,0,0,195,7679,0,0,300,18000,0,0,68,1208,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,170 +17 1461 . G <*> 0 . DP=5;I16=2,3,0,0,179,6627,0,0,300,18000,0,0,65,1137,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,157 +17 1462 . C <*> 0 . DP=4;I16=1,2,0,0,119,4745,0,0,180,10800,0,0,46,786,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,112 +17 1463 . T <*> 0 . DP=4;I16=2,2,0,0,151,5805,0,0,240,14400,0,0,61,1021,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,139 +17 1464 . G <*> 0 . DP=5;I16=2,3,0,0,165,5535,0,0,300,18000,0,0,59,975,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,144 +17 1465 . T <*> 0 . DP=5;I16=2,3,0,0,191,7315,0,0,300,18000,0,0,58,938,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,166 +17 1466 . G <*> 0 . DP=5;I16=2,3,0,0,187,7027,0,0,300,18000,0,0,57,911,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,163 +17 1467 . A <*> 0 . DP=5;I16=2,3,0,0,177,6425,0,0,300,18000,0,0,56,894,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,155 +17 1468 . A <*> 0 . DP=5;I16=2,3,0,0,181,6661,0,0,300,18000,0,0,55,887,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,158 +17 1469 . C <*> 0 . DP=5;I16=2,3,0,0,184,6832,0,0,300,18000,0,0,54,890,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,160 +17 1470 . T <*> 0 . DP=5;I16=2,3,0,0,190,7290,0,0,300,18000,0,0,53,903,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,165 +17 1471 . G <*> 0 . DP=4;I16=2,2,0,0,139,4921,0,0,240,14400,0,0,52,874,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,128 +17 1472 . T <*> 0 . DP=4;I16=2,2,0,0,146,5482,0,0,240,14400,0,0,51,851,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,134 +17 1473 . C <*> 0 . DP=4;I16=2,2,0,0,153,5877,0,0,240,14400,0,0,50,834,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,140 +17 1474 . C <*> 0 . DP=4;I16=2,2,0,0,154,5950,0,0,240,14400,0,0,49,823,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,141 +17 1475 . T <*> 0 . DP=4;I16=2,2,0,0,170,7234,0,0,240,14400,0,0,48,818,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,155 +17 1476 . T <*> 0 . DP=4;I16=2,2,0,0,153,5877,0,0,240,14400,0,0,47,819,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,140 +17 1477 . G <*> 0 . DP=4;I16=2,2,0,0,151,5725,0,0,240,14400,0,0,46,826,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,138 +17 1478 . G <*> 0 . DP=4;I16=1,2,0,0,116,4494,0,0,180,10800,0,0,42,830,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,109 +17 1479 . C <*> 0 . DP=3;I16=1,2,0,0,112,4230,0,0,180,10800,0,0,42,854,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,106 +17 1480 . C <*> 0 . DP=3;I16=1,2,0,0,109,4045,0,0,180,10800,0,0,42,882,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,103 +17 1481 . T <*> 0 . DP=3;I16=1,2,0,0,111,4133,0,0,180,10800,0,0,42,914,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,105 +17 1482 . G <*> 0 . DP=2;I16=1,1,0,0,75,2825,0,0,120,7200,0,0,43,949,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,75 +17 1483 . T <*> 0 . DP=3;I16=1,2,0,0,105,3827,0,0,180,10800,0,0,44,986,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,100 +17 1484 . T <*> 0 . DP=3;I16=1,2,0,0,111,4229,0,0,180,10800,0,0,46,1026,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,106 +17 1485 . T <*> 0 . DP=3;I16=1,2,0,0,98,3340,0,0,180,10800,0,0,48,1070,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,93 +17 1486 . G <*> 0 . DP=3;I16=1,2,0,0,115,4411,0,0,180,10800,0,0,50,1118,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,108 +17 1487 . G <*> 0 . DP=3;I16=1,2,0,0,103,3537,0,0,180,10800,0,0,52,1170,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,97 +17 1488 . T <*> 0 . DP=3;I16=1,2,0,0,108,3914,0,0,180,10800,0,0,54,1226,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,102 +17 1489 . G <*> 0 . DP=3;I16=1,2,0,0,99,3293,0,0,180,10800,0,0,56,1286,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,93 +17 1490 . A <*> 0 . DP=3;I16=1,2,0,0,97,3541,0,0,180,10800,0,0,57,1299,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,94 +17 1491 . C <*> 0 . DP=3;I16=1,2,0,0,82,2558,0,0,180,10800,0,0,58,1314,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,79 +17 1492 . G <*> 0 . DP=3;I16=1,2,0,0,106,3764,0,0,180,10800,0,0,59,1331,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,100 +17 1493 . G <*> 0 . DP=3;I16=1,2,0,0,113,4273,0,0,180,10800,0,0,60,1350,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,106 +17 1494 . G <*> 0 . DP=3;I16=1,2,0,0,113,4317,0,0,180,10800,0,0,61,1371,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,107 +17 1495 . T <*> 0 . DP=3;I16=1,2,0,0,111,4149,0,0,180,10800,0,0,62,1394,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,105 +17 1496 . G <*> 0 . DP=3;I16=1,2,0,0,114,4356,0,0,180,10800,0,0,63,1419,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,107 +17 1497 . A <*> 0 . DP=3;I16=1,2,0,0,120,4814,0,0,180,10800,0,0,64,1446,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,113 +17 1498 . G <*> 0 . DP=3;I16=1,2,0,0,119,4729,0,0,180,10800,0,0,65,1475,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,112 +17 1499 . G <*> 0 . DP=3;I16=1,2,0,0,114,4358,0,0,180,10800,0,0,66,1506,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,108 +17 1500 . A <*> 0 . DP=3;I16=1,2,0,0,122,4982,0,0,180,10800,0,0,67,1539,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,115 +17 1501 . G <*> 0 . DP=3;I16=1,2,0,0,106,3806,0,0,180,10800,0,0,68,1574,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,100 +17 1502 . C <*> 0 . DP=3;I16=1,2,0,0,111,4149,0,0,180,10800,0,0,69,1611,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,105 +17 1503 . A <*> 0 . DP=3;I16=1,2,0,0,115,4469,0,0,180,10800,0,0,70,1650,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,109 +17 1504 . G <*> 0 . DP=3;I16=1,2,0,0,118,4654,0,0,180,10800,0,0,71,1691,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,111 +17 1505 . G <*> 0 . DP=3;I16=1,2,0,0,121,4901,0,0,180,10800,0,0,72,1734,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,114 +17 1506 . G <*> 0 . DP=3;I16=1,2,0,0,118,4692,0,0,180,10800,0,0,73,1779,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,112 +17 1507 . A <*> 0 . DP=3;I16=1,2,0,0,121,4885,0,0,180,10800,0,0,74,1826,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,114 +17 1508 . C <*> 0 . DP=3;I16=1,2,0,0,118,4642,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,112 +17 1509 . A <*> 0 . DP=3;I16=1,2,0,0,129,5553,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,122 +17 1510 . G <*> 0 . DP=3;I16=1,2,0,0,118,4658,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,111 +17 1511 . A <*> 0 . DP=3;I16=1,2,0,0,116,4552,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,110 +17 1512 . A <*> 0 . DP=3;I16=1,2,0,0,115,4569,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,110 +17 1513 . G <*> 0 . DP=3;I16=1,2,0,0,114,4370,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,108 +17 1514 . G <*> 0 . DP=3;I16=1,2,0,0,115,4427,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,108 +17 1515 . G <*> 0 . DP=3;I16=1,2,0,0,107,3837,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,101 +17 1516 . T <*> 0 . DP=3;I16=1,2,0,0,112,4182,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,106 +17 1517 . C <*> 0 . DP=3;I16=1,2,0,0,102,3542,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,97 +17 1518 . C <*> 0 . DP=3;I16=1,2,0,0,101,3515,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,96 +17 1519 . T <*> 0 . DP=3;I16=1,2,0,0,117,4601,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,110 +17 1520 . G <*> 0 . DP=3;I16=1,2,0,0,110,4058,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,104 +17 1521 . C <*> 0 . DP=3;I16=1,2,0,0,93,3051,0,0,180,10800,0,0,74,1826,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,88 +17 1522 . G <*> 0 . DP=3;I16=1,2,0,0,96,3122,0,0,180,10800,0,0,73,1779,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,91 +17 1523 . T <*> 0 . DP=3;I16=1,2,0,0,114,4346,0,0,180,10800,0,0,72,1734,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,108 +17 1524 . G <*> 0 . DP=3;I16=1,2,0,0,109,4035,0,0,180,10800,0,0,71,1691,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,103 +17 1525 . C <*> 0 . DP=3;I16=1,2,0,0,119,4725,0,0,180,10800,0,0,70,1650,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,112 +17 1526 . C <*> 0 . DP=3;I16=1,2,0,0,112,4226,0,0,180,10800,0,0,69,1611,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,106 +17 1527 . C <*> 0 . DP=3;I16=1,2,0,0,119,4721,0,0,180,10800,0,0,68,1574,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,112 +17 1528 . T <*> 0 . DP=3;I16=1,2,0,0,120,4818,0,0,180,10800,0,0,67,1539,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,113 +17 1529 . G <*> 0 . DP=3;I16=1,2,0,0,111,4121,0,0,180,10800,0,0,66,1506,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,104 +17 1530 . C <*> 0 . DP=3;I16=1,2,0,0,112,4182,0,0,180,10800,0,0,65,1475,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,106 +17 1531 . C <*> 0 . DP=3;I16=1,2,0,0,111,4145,0,0,180,10800,0,0,64,1446,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,105 +17 1532 . T <*> 0 . DP=3;I16=1,2,0,0,127,5379,0,0,180,10800,0,0,63,1419,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,120 +17 1533 . T <*> 0 . DP=3;I16=1,2,0,0,113,4325,0,0,180,10800,0,0,62,1394,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,107 +17 1534 . C <*> 0 . DP=3;I16=1,2,0,0,115,4437,0,0,180,10800,0,0,61,1371,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,109 +17 1535 . A <*> 0 . DP=3;I16=1,2,0,0,104,3750,0,0,180,10800,0,0,60,1350,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,99 +17 1536 . C <*> 0 . DP=3;I16=1,2,0,0,116,4488,0,0,180,10800,0,0,59,1331,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,110 +17 1537 . A <*> 0 . DP=3;I16=1,2,0,0,122,4966,0,0,180,10800,0,0,58,1314,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,115 +17 1538 . A <*> 0 . DP=3;I16=1,2,0,0,119,4753,0,0,180,10800,0,0,57,1299,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,112 +17 1539 . G <*> 0 . DP=3;I16=1,2,0,0,124,5134,0,0,180,10800,0,0,56,1286,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,117 +17 1540 . C <*> 0 . DP=3;I16=1,2,0,0,108,3920,0,0,180,10800,0,0,54,1226,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,102 +17 1541 . C <*> 0 . DP=3;I16=1,2,0,0,114,4374,0,0,180,10800,0,0,52,1170,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,108 +17 1542 . C <*> 0 . DP=4;I16=2,2,0,0,143,5227,0,0,240,14400,0,0,50,1118,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,131 +17 1543 . C <*> 0 . DP=4;I16=2,2,0,0,148,5586,0,0,240,14400,0,0,49,1071,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,136 +17 1544 . T <*> 0 . DP=4;I16=2,2,0,0,162,6562,0,0,240,14400,0,0,48,1030,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,148 +17 1545 . G <*> 0 . DP=4;I16=2,2,0,0,141,5057,0,0,240,14400,0,0,47,995,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,129 +17 1546 . G <*> 0 . DP=3;I16=1,2,0,0,117,4601,0,0,180,10800,0,0,47,965,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,110 +17 1547 . A <*> 0 . DP=3;I16=1,2,0,0,119,4725,0,0,180,10800,0,0,47,939,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,112 +17 1548 . A <*> 0 . DP=3;I16=1,2,0,0,122,4994,0,0,180,10800,0,0,47,917,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,115 +17 1549 . G <*> 0 . DP=3;I16=1,2,0,0,121,4897,0,0,180,10800,0,0,47,899,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,114 +17 1550 . G <*> 0 . DP=3;I16=1,2,0,0,116,4506,0,0,180,10800,0,0,47,885,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,109 +17 1551 . A <*> 0 . DP=3;I16=1,2,0,0,114,4356,0,0,180,10800,0,0,47,875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,107 +17 1552 . A <*> 0 . DP=3;I16=1,2,0,0,117,4577,0,0,180,10800,0,0,47,869,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,110 +17 1553 . A <*> 0 . DP=3;I16=1,2,0,0,122,4970,0,0,180,10800,0,0,47,867,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,115 +17 1554 . G <*> 0 . DP=3;I16=1,2,0,0,107,3841,0,0,180,10800,0,0,47,869,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,101 +17 1555 . T <*> 0 . DP=3;I16=1,2,0,0,114,4374,0,0,180,10800,0,0,47,875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,108 +17 1556 . T <*> 0 . DP=3;I16=1,2,0,0,116,4486,0,0,180,10800,0,0,47,885,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,110 +17 1557 . G <*> 0 . DP=3;I16=1,2,0,0,107,3821,0,0,180,10800,0,0,47,899,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,101 +17 1558 . T <*> 0 . DP=3;I16=1,2,0,0,118,4646,0,0,180,10800,0,0,47,917,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,112 +17 1559 . T <*> 0 . DP=3;I16=1,2,0,0,109,4043,0,0,180,10800,0,0,46,890,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,103 +17 1560 . T <*> 0 . DP=3;I16=1,2,0,0,119,4725,0,0,180,10800,0,0,45,869,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,112 +17 1561 . T <*> 0 . DP=3;I16=1,2,0,0,113,4257,0,0,180,10800,0,0,44,854,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,106 +17 1562 . G <*> 0 . DP=3;I16=1,2,0,0,115,4421,0,0,180,10800,0,0,43,845,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,108 +17 1563 . G <*> 0 . DP=3;I16=1,2,0,0,114,4370,0,0,180,10800,0,0,42,842,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,108 +17 1564 . G <*> 0 . DP=3;I16=1,2,0,0,101,3421,0,0,180,10800,0,0,41,845,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,95 +17 1565 . A <*> 0 . DP=2;I16=1,1,0,0,71,2533,0,0,120,7200,0,0,41,853,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,71 +17 1566 . T <*> 0 . DP=2;I16=1,1,0,0,78,3042,0,0,120,7200,0,0,41,865,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,78 +17 1567 . C <*> 0 . DP=2;I16=1,1,0,0,72,2610,0,0,120,7200,0,0,41,881,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,72 +17 1568 . T <*> 0 . DP=2;I16=1,1,0,0,74,2756,0,0,120,7200,0,0,40,850,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,74 +17 1569 . C <*> 0 . DP=2;I16=1,1,0,0,76,2890,0,0,120,7200,0,0,39,821,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,76 +17 1570 . T <*> 0 . DP=2;I16=1,1,0,0,71,2545,0,0,120,7200,0,0,38,794,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,71 +17 1571 . G <*> 0 . DP=2;I16=1,1,0,0,70,2450,0,0,120,7200,0,0,37,769,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,70 +17 1572 . C <*> 0 . DP=2;I16=1,1,0,0,70,2522,0,0,120,7200,0,0,36,746,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,70 +17 1573 . A <*> 0 . DP=2;I16=1,0,0,0,40,1600,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,40 +17 1574 . C <*> 0 . DP=2;I16=1,0,0,0,38,1444,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,38 +17 1575 . C <*> 0 . DP=2;I16=1,1,0,0,71,2545,0,0,120,7200,0,0,33,689,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,71 +17 1576 . C <*> 0 . DP=2;I16=1,1,0,0,78,3050,0,0,120,7200,0,0,32,674,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,78 +17 1577 . T <*> 0 . DP=2;I16=1,1,0,0,77,2989,0,0,120,7200,0,0,31,661,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,77 +17 1578 . C <*> 0 . DP=2;I16=1,1,0,0,77,2977,0,0,120,7200,0,0,30,650,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,77 +17 1579 . A <*> 0 . DP=2;I16=1,1,0,0,80,3200,0,0,120,7200,0,0,29,641,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,80 +17 1580 . G <*> 0 . DP=2;I16=1,1,0,0,77,2977,0,0,120,7200,0,0,28,634,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,77 +17 1581 . C <*> 0 . DP=2;I16=1,1,0,0,71,2581,0,0,120,7200,0,0,27,629,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,71 +17 1582 . C <*> 0 . DP=2;I16=1,1,0,0,75,2853,0,0,120,7200,0,0,26,626,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,75 +17 1583 . T <*> 0 . DP=2;I16=1,1,0,0,74,2810,0,0,120,7200,0,0,25,625,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,74 +17 1584 . G <*> 0 . DP=1;I16=1,0,0,0,39,1521,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,39 +17 1585 . G <*> 0 . DP=1;I16=1,0,0,0,30,900,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,30 +17 1586 . A <*> 0 . DP=1;I16=1,0,0,0,42,1764,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,42 +17 1587 . C <*> 0 . DP=1;I16=1,0,0,0,31,961,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,31 +17 1588 . A <*> 0 . DP=1;I16=1,0,0,0,41,1681,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,41 +17 1589 . A <*> 0 . DP=1;I16=1,0,0,0,42,1764,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,42 +17 1590 . C <*> 0 . DP=2;I16=1,1,0,0,71,2525,0,0,120,7200,0,0,25,625,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,71 +17 1591 . T <*> 0 . DP=2;I16=1,1,0,0,73,2705,0,0,120,7200,0,0,26,626,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,73 +17 1592 . T <*> 0 . DP=2;I16=1,1,0,0,62,1972,0,0,120,7200,0,0,27,629,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,62 +17 1593 . G <*> 0 . DP=2;I16=1,1,0,0,60,2042,0,0,120,7200,0,0,28,634,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,60 +17 1594 . T <*> 0 . DP=2;I16=1,1,0,0,80,3200,0,0,120,7200,0,0,29,641,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,80 +17 1595 . G <*> 0 . DP=2;I16=1,1,0,0,69,2421,0,0,120,7200,0,0,30,650,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,69 +17 1596 . C <*> 0 . DP=2;I16=1,1,0,0,74,2756,0,0,120,7200,0,0,31,661,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,74 +17 1597 . C <*> 0 . DP=2;I16=1,1,0,0,73,2749,0,0,120,7200,0,0,32,674,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,73 +17 1598 . C <*> 0 . DP=2;I16=1,1,0,0,68,2512,0,0,120,7200,0,0,33,689,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,68 +17 1599 . A <*> 0 . DP=2;I16=1,1,0,0,76,2890,0,0,120,7200,0,0,34,706,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,76 +17 1600 . T <*> 0 . DP=2;I16=1,1,0,0,79,3125,0,0,120,7200,0,0,35,725,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,79 +17 1601 . C <*> 0 . DP=2;I16=1,1,0,0,78,3092,0,0,120,7200,0,0,36,746,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,78 +17 1602 . T <*> 0 . DP=2;I16=1,1,0,0,85,3617,0,0,120,7200,0,0,37,769,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,85 +17 1603 . G <*> 0 . DP=2;I16=1,1,0,0,75,2817,0,0,120,7200,0,0,38,794,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,75 +17 1604 . G <*> 0 . DP=2;I16=1,1,0,0,66,2178,0,0,120,7200,0,0,39,821,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,66 +17 1605 . T <*> 0 . DP=2;I16=1,1,0,0,61,1901,0,0,120,7200,0,0,40,850,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,61 +17 1606 . G <*> 0 . DP=2;I16=1,1,0,0,56,1570,0,0,120,7200,0,0,41,881,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,56 +17 1607 . A <*> 0 . DP=2;I16=1,1,0,0,55,1825,0,0,120,7200,0,0,42,914,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,55 +17 1608 . C <*> 0 . DP=2;I16=1,1,0,0,62,2050,0,0,120,7200,0,0,43,949,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,62 +17 1609 . C <*> 0 . DP=2;I16=1,1,0,0,71,2561,0,0,120,7200,0,0,44,986,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,71 +17 1610 . C <*> 0 . DP=2;I16=1,1,0,0,57,1889,0,0,120,7200,0,0,45,1025,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,57 +17 1611 . C <*> 0 . DP=2;I16=1,1,0,0,67,2329,0,0,120,7200,0,0,46,1066,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,67 +17 1612 . T <*> 0 . DP=2;I16=1,1,0,0,83,3457,0,0,120,7200,0,0,47,1109,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,83 +17 1613 . C <*> 0 . DP=2;I16=1,1,0,0,63,2129,0,0,120,7200,0,0,48,1154,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,63 +17 1614 . A <*> 0 . DP=2;I16=1,1,0,0,69,2465,0,0,120,7200,0,0,49,1201,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,69 +17 1615 . C <*> 0 . DP=2;I16=1,1,0,0,51,1445,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,51 +17 1616 . T <*> 0 . DP=2;I16=1,0,0,0,42,1764,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,42 +17 1617 . C <*> 0 . DP=2;I16=1,0,0,0,42,1764,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,42 +17 1618 . A <*> 0 . DP=2;I16=1,1,0,0,81,3281,0,0,120,7200,0,0,49,1201,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,81 +17 1619 . G <*> 0 . DP=2;I16=1,1,0,0,67,2269,0,0,120,7200,0,0,48,1154,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,67 +17 1620 . C <*> 0 . DP=2;I16=1,1,0,0,56,1906,0,0,120,7200,0,0,47,1109,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,56 +17 1621 . C <*> 0 . DP=2;I16=1,1,0,0,56,1810,0,0,120,7200,0,0,46,1066,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,56 +17 1622 . A <*> 0 . DP=2;I16=1,1,0,0,52,1640,0,0,120,7200,0,0,45,1025,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,52 +17 1623 . C <*> 0 . DP=2;I16=1,0,0,0,37,1369,0,0,60,3600,0,0,19,361,0,0;QS=1,0;MQ0F=0 PL 0,3,37 +17 1624 . C <*> 0 . DP=2;I16=1,0,0,0,39,1521,0,0,60,3600,0,0,18,324,0,0;QS=1,0;MQ0F=0 PL 0,3,39 +17 1625 . A <*> 0 . DP=2;I16=1,1,0,0,80,3202,0,0,120,7200,0,0,42,914,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,80 +17 1626 . G <*> 0 . DP=2;I16=1,1,0,0,63,2009,0,0,120,7200,0,0,41,881,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,63 +17 1627 . A <*> 0 . DP=2;I16=1,1,0,0,72,2610,0,0,120,7200,0,0,40,850,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,72 +17 1628 . C <*> 0 . DP=2;I16=1,1,0,0,57,1805,0,0,120,7200,0,0,39,821,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,57 +17 1629 . T <*> 0 . DP=2;I16=1,1,0,0,79,3161,0,0,120,7200,0,0,38,794,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,79 +17 1630 . T <*> 0 . DP=2;I16=1,1,0,0,73,2665,0,0,120,7200,0,0,37,769,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,73 +17 1631 . C <*> 0 . DP=2;I16=1,1,0,0,61,2041,0,0,120,7200,0,0,36,746,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,61 +17 1632 . C <*> 0 . DP=2;I16=1,1,0,0,61,2041,0,0,120,7200,0,0,35,725,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,61 +17 1633 . A <*> 0 . DP=2;I16=1,1,0,0,73,2705,0,0,120,7200,0,0,34,706,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,73 +17 1634 . C <*> 0 . DP=2;I16=1,1,0,0,59,1885,0,0,120,7200,0,0,33,689,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,59 +17 1635 . G <*> 0 . DP=2;I16=1,1,0,0,59,1741,0,0,120,7200,0,0,32,674,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,59 +17 1636 . A <*> 0 . DP=2;I16=1,1,0,0,66,2306,0,0,120,7200,0,0,31,661,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,66 +17 1637 . C <*> 0 . DP=2;I16=1,1,0,0,60,1898,0,0,120,7200,0,0,30,650,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,60 +17 1638 . A <*> 0 . DP=2;I16=1,1,0,0,78,3042,0,0,120,7200,0,0,29,641,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,78 +17 1639 . G <*> 0 . DP=2;I16=1,1,0,0,68,2314,0,0,120,7200,0,0,28,634,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,68 +17 1640 . G <*> 0 . DP=2;I16=1,1,0,0,51,1481,0,0,120,7200,0,0,27,629,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,51 +17 1641 . C <*> 0 . DP=3;I16=1,1,0,0,65,2125,0,0,120,7200,0,0,26,626,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,65 +17 1642 . T <*> 0 . DP=3;I16=1,2,0,0,108,3888,0,0,180,10800,0,0,50,1250,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,102 +17 1643 . C <*> 0 . DP=2;I16=0,2,0,0,61,1873,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,56 +17 1644 . C <*> 0 . DP=2;I16=0,2,0,0,59,1745,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,54 +17 1645 . A <*> 0 . DP=2;I16=0,2,0,0,53,1417,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,49 +17 1646 . G <*> 0 . DP=2;I16=0,2,0,0,53,1409,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,48 +17 1647 . C <*> 0 . DP=2;I16=0,2,0,0,39,761,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,35 +17 1648 . C <*> 0 . DP=2;I16=0,2,0,0,48,1184,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,44 +17 1649 . T <*> 0 . DP=2;I16=0,2,0,0,61,1901,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,56 +17 1650 . C <*> 0 . DP=2;I16=0,1,0,0,13,169,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,13 +17 1651 . G <*> 0 . DP=3;I16=1,2,0,0,92,2840,0,0,149,8041,0,0,50,1250,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,86 +17 1652 . G <*> 0 . DP=3;I16=1,1,0,0,59,1781,0,0,89,4441,0,0,26,626,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,54 +17 1653 . C <*> 0 . DP=3;I16=1,2,0,0,95,3181,0,0,149,8041,0,0,52,1254,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,82 +17 1654 . A <*> 0 . DP=3;I16=1,2,0,0,91,2933,0,0,149,8041,0,0,53,1259,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,78 +17 1655 . C <*> 0 . DP=3;I16=1,2,0,0,88,2942,0,0,149,8041,0,0,54,1266,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,79 +17 1656 . C <*> 0 . DP=3;I16=1,2,0,0,93,2969,0,0,149,8041,0,0,55,1275,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,80 +17 1657 . T <*> 0 . DP=3;I16=1,2,0,0,104,3770,0,0,149,8041,0,0,56,1286,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,85 +17 1658 . T <*> 0 . DP=3;I16=1,2,0,0,97,3205,0,0,149,8041,0,0,57,1299,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,91 +17 1659 . C <*> 0 . DP=4;I16=1,2,0,0,92,2994,0,0,149,8041,0,0,58,1314,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,80 +17 1660 . A <*> 0 . DP=4;I16=1,3,0,0,155,6015,0,0,209,11641,0,0,84,1956,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,127 +17 1661 . G <*> 0 . DP=4;I16=1,3,0,0,118,3508,0,0,209,11641,0,0,85,1975,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,98 +17 1662 . C <*> 0 . DP=4;I16=1,3,0,0,123,3901,0,0,209,11641,0,0,86,1996,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,100 +17 1663 . C <*> 0 . DP=4;I16=1,3,0,0,124,3894,0,0,209,11641,0,0,87,2019,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,101 +17 1664 . A <*> 0 . DP=4;I16=1,3,0,0,130,4468,0,0,209,11641,0,0,88,2044,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,109 +17 1665 . T C,<*> 0 . DP=4;I16=0,2,1,1,68,2330,58,1924,120,7200,89,4441,50,1250,39,821;QS=0.591304,0.408696,0;VDB=0.1;SGB=-0.453602;RPB=0;MQB=0.5;MQSB=1;BQB=1;MQ0F=0 PL 35,0,51,41,57,90 +17 1666 . G <*> 0 . DP=4;I16=1,3,0,0,129,4165,0,0,209,11641,0,0,88,2002,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,111 +17 1667 . G <*> 0 . DP=4;I16=1,3,0,0,144,5304,0,0,209,11641,0,0,87,1939,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,115 +17 1668 . A <*> 0 . DP=4;I16=1,3,0,0,153,5865,0,0,209,11641,0,0,86,1882,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,124 +17 1669 . C <*> 0 . DP=4;I16=1,3,0,0,140,4974,0,0,209,11641,0,0,85,1831,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,115 +17 1670 . A <*> 0 . DP=4;I16=1,3,0,0,158,6270,0,0,209,11641,0,0,84,1786,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,129 +17 1671 . G <*> 0 . DP=4;I16=1,3,0,0,133,4551,0,0,209,11641,0,0,83,1747,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,106 +17 1672 . T <*> 0 . DP=4;I16=1,3,0,0,134,4662,0,0,209,11641,0,0,82,1714,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,111 +17 1673 . T <*> 0 . DP=4;I16=1,3,0,0,138,4884,0,0,209,11641,0,0,81,1687,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,112 +17 1674 . C <*> 0 . DP=4;I16=1,3,0,0,115,3581,0,0,209,11641,0,0,80,1666,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,96 +17 1675 . C <*> 0 . DP=4;I16=1,2,0,0,79,2323,0,0,149,8041,0,0,64,1426,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,65 +17 1676 . G <*> 0 . DP=4;I16=1,2,0,0,105,3693,0,0,149,8041,0,0,53,1017,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,96 +17 1677 . C <*> 0 . DP=4;I16=1,2,0,0,91,3129,0,0,149,8041,0,0,51,963,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,74 +17 1678 . C <*> 0 . DP=4;I16=1,2,0,0,102,3590,0,0,149,8041,0,0,49,913,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,83 +17 1679 . A <*> 0 . DP=4;I16=1,2,0,0,125,5211,0,0,149,8041,0,0,47,867,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,106 +17 1680 . G <*> 0 . DP=4;I16=1,3,0,0,134,4686,0,0,209,11641,0,0,70,1450,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,108 +17 1681 . C <*> 0 . DP=4;I16=1,2,0,0,85,2749,0,0,149,8041,0,0,59,1331,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,69 +17 1682 . G <*> 0 . DP=4;I16=1,3,0,0,111,3081,0,0,209,11641,0,0,66,1378,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,98 +17 1683 . T <*> 0 . DP=4;I16=1,2,0,0,103,3553,0,0,149,8041,0,0,39,723,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,91 +17 1684 . T <*> 0 . DP=4;I16=1,3,0,0,133,4611,0,0,209,11641,0,0,62,1322,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,107 +17 1685 . G <*> 0 . DP=4;I16=1,3,0,0,128,4242,0,0,209,11641,0,0,60,1300,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,110 +17 1686 . C <*> 0 . DP=4;I16=1,3,0,0,127,4127,0,0,209,11641,0,0,58,1282,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,103 +17 1687 . C <*> 0 . DP=4;I16=1,3,0,0,129,4325,0,0,209,11641,0,0,56,1268,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,106 +17 1688 . C <*> 0 . DP=4;I16=1,3,0,0,147,5445,0,0,209,11641,0,0,54,1258,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,120 +17 1689 . T A,<*> 0 . DP=4;I16=1,2,0,1,111,4185,33,1089,149,8041,60,3600,27,627,25,625;QS=0.744186,0.255814,0;SGB=-0.379885;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL 21,0,79,30,82,106 +17 1690 . C <*> 0 . DP=4;I16=1,3,0,0,120,3996,0,0,209,11641,0,0,50,1250,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,95 +17 1691 . T <*> 0 . DP=2;I16=1,1,0,0,71,2633,0,0,89,4441,0,0,50,1250,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,57 +17 1692 . G <*> 0 . DP=2;I16=1,1,0,0,73,2705,0,0,89,4441,0,0,50,1250,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,61 +17 1693 . T <*> 0 . DP=4;I16=3,1,0,0,130,4356,0,0,209,11641,0,0,50,1250,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,104 +17 1694 . T <*> 0 . DP=4;I16=3,1,0,0,133,4437,0,0,209,11641,0,0,52,1252,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,114 +17 1695 . C <*> 0 . DP=4;I16=3,1,0,0,143,5117,0,0,209,11641,0,0,54,1258,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,121 +17 1696 . T <*> 0 . DP=4;I16=3,1,0,0,138,5226,0,0,209,11641,0,0,56,1268,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,108 +17 1697 . G <*> 0 . DP=4;I16=3,1,0,0,132,4424,0,0,209,11641,0,0,58,1282,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,112 +17 1698 . C <*> 0 . DP=4;I16=3,1,0,0,135,4661,0,0,209,11641,0,0,60,1300,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,111 +17 1699 . T <*> 0 . DP=4;I16=3,1,0,0,144,5250,0,0,209,11641,0,0,62,1322,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,115 +17 1700 . G <*> 0 . DP=4;I16=3,1,0,0,133,4485,0,0,209,11641,0,0,64,1348,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,110 +17 1701 . T <*> 0 . DP=4;I16=3,1,0,0,152,5794,0,0,209,11641,0,0,66,1378,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,125 +17 1702 . T <*> 0 . DP=4;I16=3,1,0,0,141,5099,0,0,209,11641,0,0,67,1363,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,115 +17 1703 . T <*> 0 . DP=4;I16=3,1,0,0,141,5087,0,0,209,11641,0,0,68,1354,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,114 +17 1704 . T <*> 0 . DP=5;I16=4,1,0,0,163,5477,0,0,269,15241,0,0,69,1351,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,128 +17 1705 . C <*> 0 . DP=5;I16=4,1,0,0,156,5206,0,0,269,15241,0,0,71,1355,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,120 +17 1706 . T <*> 0 . DP=5;I16=4,1,0,0,193,7555,0,0,269,15241,0,0,73,1367,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,145 +17 1707 . C <*> 0 . DP=5;I16=4,1,0,0,173,6169,0,0,269,15241,0,0,75,1387,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,134 +17 1708 . T <*> 0 . DP=5;I16=4,1,0,0,173,6131,0,0,269,15241,0,0,77,1415,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,132 +17 1709 . A <*> 0 . DP=5;I16=4,1,0,0,168,5822,0,0,269,15241,0,0,79,1451,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,131 +17 1710 . C <*> 0 . DP=5;I16=4,1,0,0,158,5102,0,0,269,15241,0,0,81,1495,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,128 +17 1711 . C <*> 0 . DP=5;I16=4,1,0,0,174,6146,0,0,269,15241,0,0,83,1547,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,138 +17 1712 . A <*> 0 . DP=5;I16=4,1,0,0,175,6151,0,0,269,15241,0,0,85,1607,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,136 +17 1713 . G <*> 0 . DP=5;I16=3,1,0,0,133,4619,0,0,209,11641,0,0,78,1594,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,118 +17 1714 . A <*> 0 . DP=5;I16=4,0,0,0,139,4917,0,0,209,11641,0,0,77,1607,0,0;QS=1,0;MQ0F=0 PL 0,12,101 +17 1715 . A <*> 0 . DP=5;I16=4,1,0,0,182,6670,0,0,269,15241,0,0,91,1835,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,145 +17 1716 . G <*> 0 . DP=5;I16=4,1,0,0,165,5679,0,0,269,15241,0,0,93,1927,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,129 +17 1717 . T <*> 0 . DP=5;I16=4,1,0,0,156,5082,0,0,269,15241,0,0,95,2027,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,122 +17 1718 . G <*> 0 . DP=5;I16=4,1,0,0,158,5140,0,0,269,15241,0,0,97,2135,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,124 +17 1719 . C <*> 0 . DP=5;I16=4,0,0,0,135,4797,0,0,209,11641,0,0,90,2100,0,0;QS=1,0;MQ0F=0 PL 0,12,98 +17 1720 . C <*> 0 . DP=5;I16=4,0,0,0,129,4625,0,0,209,11641,0,0,91,2131,0,0;QS=1,0;MQ0F=0 PL 0,12,99 +17 1721 . C <*> 0 . DP=5;I16=3,1,0,0,142,5116,0,0,209,11641,0,0,80,1900,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,119 +17 1722 . T <*> 0 . DP=5;I16=4,1,0,0,164,5866,0,0,269,15241,0,0,97,2215,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,123 +17 1723 . T <*> 0 . DP=5;I16=4,1,0,0,166,5622,0,0,269,15241,0,0,97,2245,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,130 +17 1724 . C <*> 0 . DP=5;I16=4,1,0,0,180,6718,0,0,269,15241,0,0,97,2279,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,139 +17 1725 . C <*> 0 . DP=5;I16=4,1,0,0,168,5834,0,0,269,15241,0,0,97,2317,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,132 +17 1726 . C <*> 0 . DP=5;I16=4,1,0,0,158,5268,0,0,269,15241,0,0,97,2359,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,122 +17 1727 . T <*> 0 . DP=5;I16=3,1,0,0,151,5813,0,0,209,11641,0,0,74,1826,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,120 +17 1728 . C <*> 0 . DP=5;I16=4,1,0,0,184,6832,0,0,269,15241,0,0,98,2356,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,144 +17 1729 . C <*> 0 . DP=5;I16=3,1,0,0,153,5879,0,0,209,11641,0,0,74,1738,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,128 +17 1730 . T <*> 0 . DP=5;I16=4,1,0,0,188,7144,0,0,269,15241,0,0,99,2325,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,148 +17 1731 . C <*> 0 . DP=5;I16=4,1,0,0,179,6673,0,0,269,15241,0,0,99,2291,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,140 +17 1732 . A <*> 0 . DP=5;I16=4,1,0,0,186,7018,0,0,269,15241,0,0,99,2261,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,143 +17 1733 . C <*> 0 . DP=5;I16=4,1,0,0,170,5934,0,0,269,15241,0,0,99,2235,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,136 +17 1734 . C <*> 0 . DP=5;I16=4,1,0,0,176,6536,0,0,269,15241,0,0,99,2213,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,141 +17 1735 . T <*> 0 . DP=5;I16=4,1,0,0,193,7605,0,0,269,15241,0,0,99,2195,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,148 +17 1736 . G <*> 0 . DP=5;I16=3,1,0,0,142,5070,0,0,209,11641,0,0,74,1556,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,118 +17 1737 . A <*> 0 . DP=5;I16=4,1,0,0,168,6138,0,0,269,15241,0,0,99,2171,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,131 +17 1738 . C <*> 0 . DP=5;I16=4,1,0,0,164,5714,0,0,269,15241,0,0,99,2165,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,130 +17 1739 . C <*> 0 . DP=5;I16=3,1,0,0,163,6649,0,0,209,11641,0,0,74,1538,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,135 +17 1740 . A <*> 0 . DP=5;I16=4,1,0,0,179,6691,0,0,269,15241,0,0,99,2165,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,139 +17 1741 . C <*> 0 . DP=5;I16=4,1,0,0,167,5861,0,0,269,15241,0,0,99,2171,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,136 +17 1742 . T <*> 0 . DP=5;I16=4,1,0,0,188,7314,0,0,269,15241,0,0,99,2181,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,144 +17 1743 . C <*> 0 . DP=5;I16=4,1,0,0,176,6240,0,0,269,15241,0,0,99,2195,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,138 +17 1744 . T <*> 0 . DP=5;I16=4,1,0,0,201,8191,0,0,269,15241,0,0,99,2213,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,156 +17 1745 . G <*> 0 . DP=5;I16=4,1,0,0,181,6773,0,0,269,15241,0,0,99,2235,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,142 +17 1746 . G <*> 0 . DP=6;I16=5,1,0,0,201,7057,0,0,329,18841,0,0,99,2261,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,151 +17 1747 . G <*> 0 . DP=6;I16=5,1,0,0,200,7248,0,0,329,18841,0,0,100,2292,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,154 +17 1748 . G <*> 0 . DP=6;I16=5,1,0,0,203,7039,0,0,329,18841,0,0,101,2329,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,154 +17 1749 . A <*> 0 . DP=7;I16=6,1,0,0,247,8875,0,0,389,22441,0,0,102,2372,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,172 +17 1750 . A <*> 0 . DP=7;I16=6,1,0,0,266,10194,0,0,389,22441,0,0,104,2422,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,187 +17 1751 . A <*> 0 . DP=7;I16=6,1,0,0,255,9549,0,0,389,22441,0,0,106,2480,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,183 +17 1752 . T <*> 0 . DP=6;I16=5,1,0,0,223,8367,0,0,360,21600,0,0,109,2545,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,170 +17 1753 . C <*> 0 . DP=6;I16=5,1,0,0,209,7747,0,0,360,21600,0,0,111,2565,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,163 +17 1754 . C <*> 0 . DP=6;I16=5,1,0,0,212,7624,0,0,360,21600,0,0,113,2589,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,163 +17 1755 . C <*> 0 . DP=6;I16=5,1,0,0,212,7854,0,0,360,21600,0,0,115,2617,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,165 +17 1756 . T <*> 0 . DP=6;I16=5,1,0,0,233,9235,0,0,360,21600,0,0,117,2649,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,179 +17 1757 . C <*> 0 . DP=6;I16=5,1,0,0,227,8795,0,0,360,21600,0,0,119,2685,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,176 +17 1758 . A <*> 0 . DP=6;I16=5,1,0,0,232,9074,0,0,360,21600,0,0,121,2725,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,177 +17 1759 . G <*> 0 . DP=6;I16=5,1,0,0,207,7355,0,0,360,21600,0,0,123,2769,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,159 +17 1760 . C <*> 0 . DP=6;I16=5,1,0,0,208,7642,0,0,360,21600,0,0,125,2817,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,159 +17 1761 . A <*> 0 . DP=6;I16=5,1,0,0,205,7409,0,0,360,21600,0,0,127,2869,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,153 +17 1762 . C <*> 0 . DP=6;I16=5,1,0,0,207,7417,0,0,360,21600,0,0,129,2925,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,160 +17 1763 . C <*> 0 . DP=6;I16=5,1,0,0,211,7629,0,0,360,21600,0,0,131,2985,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,162 +17 1764 . C <*> 0 . DP=6;I16=5,1,0,0,218,8026,0,0,360,21600,0,0,133,3049,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,167 +17 1765 . T <*> 0 . DP=6;I16=5,1,0,0,234,9192,0,0,360,21600,0,0,135,3117,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,179 +17 1766 . C <*> 0 . DP=6;I16=5,1,0,0,212,7528,0,0,360,21600,0,0,137,3189,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,162 +17 1767 . C <*> 0 . DP=6;I16=5,1,0,0,215,7771,0,0,360,21600,0,0,139,3265,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,163 +17 1768 . C <*> 0 . DP=6;I16=5,1,0,0,211,7491,0,0,360,21600,0,0,141,3345,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,160 +17 1769 . T <*> 0 . DP=6;I16=5,1,0,0,242,9834,0,0,360,21600,0,0,141,3331,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,184 +17 1770 . G <*> 0 . DP=6;I16=5,1,0,0,203,7151,0,0,360,21600,0,0,141,3325,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,158 +17 1771 . A <*> 0 . DP=6;I16=5,1,0,0,234,9160,0,0,360,21600,0,0,141,3327,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,177 +17 1772 . G <*> 0 . DP=6;I16=5,1,0,0,203,7277,0,0,360,21600,0,0,140,3286,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,159 +17 1773 . C <*> 0 . DP=6;I16=5,1,0,0,227,8625,0,0,360,21600,0,0,139,3251,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,172 +17 1774 . A <*> 0 . DP=6;I16=5,1,0,0,228,8700,0,0,360,21600,0,0,138,3222,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,172 +17 1775 . T <*> 0 . DP=6;I16=5,1,0,0,199,7101,0,0,360,21600,0,0,136,3148,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,156 +17 1776 . A <*> 0 . DP=6;I16=5,1,0,0,218,8038,0,0,360,21600,0,0,134,3078,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,166 +17 1777 . C <*> 0 . DP=6;I16=5,1,0,0,208,7460,0,0,360,21600,0,0,132,3012,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,158 +17 1778 . C <*> 0 . DP=6;I16=5,1,0,0,224,8452,0,0,360,21600,0,0,130,2950,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,172 +17 1779 . C <*> 0 . DP=6;I16=5,1,0,0,227,8671,0,0,360,21600,0,0,128,2892,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,174 +17 1780 . T <*> 0 . DP=6;I16=5,1,0,0,231,9087,0,0,360,21600,0,0,125,2789,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,177 +17 1781 . A <*> 0 . DP=6;I16=4,1,0,0,195,7619,0,0,300,18000,0,0,99,2163,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,160 +17 1782 . C <*> 0 . DP=6;I16=5,1,0,0,203,7069,0,0,360,21600,0,0,119,2601,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,156 +17 1783 . T <*> 0 . DP=6;I16=5,1,0,0,242,9860,0,0,360,21600,0,0,116,2516,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,184 +17 1784 . C <*> 0 . DP=6;I16=4,1,0,0,185,6967,0,0,300,18000,0,0,93,2037,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,151 +17 1785 . T <*> 0 . DP=5;I16=4,1,0,0,207,8659,0,0,300,18000,0,0,91,2003,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,168 +17 1786 . G <*> 0 . DP=5;I16=4,1,0,0,193,7479,0,0,300,18000,0,0,89,1973,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,158 +17 1787 . G <*> 0 . DP=5;I16=4,1,0,0,180,6520,0,0,300,18000,0,0,87,1947,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,148 +17 1788 . C <*> 0 . DP=5;I16=4,1,0,0,193,7491,0,0,300,18000,0,0,85,1925,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,158 +17 1789 . A <*> 0 . DP=5;I16=4,1,0,0,192,7402,0,0,300,18000,0,0,83,1907,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,157 +17 1790 . C <*> 0 . DP=5;I16=4,1,0,0,186,6962,0,0,300,18000,0,0,81,1893,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,153 +17 1791 . A <*> 0 . DP=5;I16=4,1,0,0,190,7288,0,0,300,18000,0,0,79,1883,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,155 +17 1792 . A <*> 0 . DP=5;I16=4,1,0,0,196,7802,0,0,300,18000,0,0,77,1877,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,161 +17 1793 . G <*> 0 . DP=5;I16=4,1,0,0,155,4877,0,0,300,18000,0,0,75,1875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,126 +17 1794 . C <*> 0 . DP=3;I16=2,1,0,0,102,3566,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,96 +17 1795 . C <*> 0 . DP=3;I16=2,1,0,0,106,3874,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,100 +17 1796 . C <*> 0 . DP=3;I16=2,1,0,0,108,3992,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,102 +17 1797 . A <*> 0 . DP=3;I16=2,1,0,0,98,3494,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,92 +17 1798 . C <*> 0 . DP=3;I16=2,1,0,0,105,3789,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,99 +17 1799 . C <*> 0 . DP=4;I16=2,2,0,0,143,5277,0,0,240,14400,0,0,75,1875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,131 +17 1800 . C <*> 0 . DP=4;I16=2,2,0,0,150,5742,0,0,240,14400,0,0,76,1876,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,138 +17 1801 . T <*> 0 . DP=4;I16=2,2,0,0,164,6762,0,0,240,14400,0,0,77,1879,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,150 +17 1802 . G <*> 0 . DP=4;I16=2,2,0,0,150,5678,0,0,240,14400,0,0,78,1884,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,137 +17 1803 . C <*> 0 . DP=4;I16=2,2,0,0,157,6193,0,0,240,14400,0,0,78,1842,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,143 +17 1804 . A <*> 0 . DP=4;I16=2,2,0,0,158,6252,0,0,240,14400,0,0,78,1804,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,144 +17 1805 . A <*> 0 . DP=4;I16=2,2,0,0,150,5684,0,0,240,14400,0,0,78,1770,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,138 +17 1806 . A <*> 0 . DP=4;I16=2,2,0,0,151,5999,0,0,240,14400,0,0,78,1740,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,139 +17 1807 . G <*> 0 . DP=4;I16=2,2,0,0,155,6057,0,0,240,14400,0,0,78,1714,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,142 +17 1808 . C <*> 0 . DP=4;I16=2,2,0,0,153,5939,0,0,240,14400,0,0,78,1692,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,140 +17 1809 . C <*> 0 . DP=4;I16=2,2,0,0,157,6187,0,0,240,14400,0,0,78,1674,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,143 +17 1810 . C <*> 0 . DP=4;I16=2,2,0,0,159,6353,0,0,240,14400,0,0,78,1660,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,145 +17 1811 . C <*> 0 . DP=4;I16=2,2,0,0,160,6402,0,0,240,14400,0,0,78,1650,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,146 +17 1812 . T <*> 0 . DP=4;I16=2,2,0,0,165,6845,0,0,240,14400,0,0,78,1644,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,151 +17 1813 . G <*> 0 . DP=4;I16=2,2,0,0,147,5441,0,0,240,14400,0,0,78,1642,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,135 +17 1814 . A <*> 0 . DP=4;I16=2,2,0,0,162,6566,0,0,240,14400,0,0,78,1644,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,148 +17 1815 . G <*> 0 . DP=4;I16=2,2,0,0,148,5508,0,0,240,14400,0,0,78,1650,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,135 +17 1816 . G <*> 0 . DP=4;I16=2,2,0,0,135,4809,0,0,240,14400,0,0,78,1660,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,124 +17 1817 . C <*> 0 . DP=4;I16=2,2,0,0,146,5370,0,0,240,14400,0,0,78,1674,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,134 +17 1818 . C <*> 0 . DP=4;I16=2,2,0,0,145,5281,0,0,240,14400,0,0,78,1692,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,132 +17 1819 . C <*> 0 . DP=4;I16=2,2,0,0,135,4641,0,0,240,14400,0,0,78,1714,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,124 +17 1820 . G <*> 0 . DP=4;I16=2,2,0,0,128,4142,0,0,240,14400,0,0,78,1740,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,117 +17 1821 . C <*> 0 . DP=4;I16=2,2,0,0,143,5143,0,0,240,14400,0,0,78,1770,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,131 +17 1822 . C <*> 0 . DP=4;I16=2,2,0,0,144,5200,0,0,240,14400,0,0,77,1755,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,131 +17 1823 . C <*> 0 . DP=4;I16=2,2,0,0,151,5705,0,0,240,14400,0,0,76,1746,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,138 +17 1824 . T <*> 0 . DP=4;I16=2,2,0,0,163,6673,0,0,240,14400,0,0,75,1743,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,149 +17 1825 . G <*> 0 . DP=4;I16=2,2,0,0,141,5015,0,0,240,14400,0,0,72,1646,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,129 +17 1826 . T <*> 0 . DP=4;I16=2,2,0,0,154,5930,0,0,240,14400,0,0,69,1555,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,141 +17 1827 . G <*> 0 . DP=4;I16=2,2,0,0,146,5406,0,0,240,14400,0,0,66,1470,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,134 +17 1828 . G <*> 0 . DP=3;I16=2,1,0,0,106,3774,0,0,180,10800,0,0,64,1390,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,100 +17 1829 . C <*> 0 . DP=3;I16=2,1,0,0,109,4021,0,0,180,10800,0,0,62,1314,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,103 +17 1830 . G <*> 0 . DP=3;I16=2,1,0,0,84,2520,0,0,180,10800,0,0,60,1242,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,80 +17 1831 . T <*> 0 . DP=3;I16=2,1,0,0,107,3865,0,0,180,10800,0,0,58,1174,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,101 +17 1832 . C <*> 0 . DP=3;I16=2,1,0,0,111,4125,0,0,180,10800,0,0,56,1110,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,105 +17 1833 . T <*> 0 . DP=3;I16=2,1,0,0,112,4206,0,0,180,10800,0,0,54,1050,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,106 +17 1834 . C <*> 0 . DP=3;I16=2,1,0,0,114,4356,0,0,180,10800,0,0,52,994,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,107 +17 1835 . T <*> 0 . DP=3;I16=2,1,0,0,122,5030,0,0,180,10800,0,0,50,942,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,115 +17 1836 . C <*> 0 . DP=3;I16=2,1,0,0,115,4425,0,0,180,10800,0,0,48,894,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,108 +17 1837 . C <*> 0 . DP=3;I16=2,1,0,0,114,4346,0,0,180,10800,0,0,46,850,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,108 +17 1838 . C <*> 0 . DP=3;I16=2,1,0,0,113,4277,0,0,180,10800,0,0,44,810,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,107 +17 1839 . T <*> 0 . DP=3;I16=2,1,0,0,126,5316,0,0,180,10800,0,0,42,774,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,119 +17 1840 . C <*> 0 . DP=3;I16=2,1,0,0,115,4417,0,0,180,10800,0,0,40,742,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,109 +17 1841 . C <*> 0 . DP=3;I16=2,1,0,0,114,4340,0,0,180,10800,0,0,38,714,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,108 +17 1842 . C <*> 0 . DP=3;I16=2,1,0,0,114,4334,0,0,180,10800,0,0,36,690,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,108 +17 1843 . T <*> 0 . DP=3;I16=2,1,0,0,114,4356,0,0,180,10800,0,0,34,670,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,107 +17 1844 . T <*> 0 . DP=3;I16=2,1,0,0,104,3656,0,0,180,10800,0,0,32,654,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,98 +17 1845 . G <*> 0 . DP=3;I16=2,1,0,0,86,2614,0,0,180,10800,0,0,30,642,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,82 +17 1846 . C <*> 0 . DP=3;I16=2,1,0,0,106,3750,0,0,180,10800,0,0,28,634,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,100 +17 1847 . T <*> 0 . DP=2;I16=1,1,0,0,76,2890,0,0,120,7200,0,0,27,629,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,76 +17 1848 . G <*> 0 . DP=2;I16=1,1,0,0,64,2066,0,0,120,7200,0,0,26,626,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,64 +17 1849 . T <*> 0 . DP=2;I16=1,1,0,0,71,2561,0,0,120,7200,0,0,25,625,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,71 +17 1850 . C <*> 0 . DP=1;I16=0,1,0,0,37,1369,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,37 +17 1851 . A <*> 0 . DP=1;I16=0,1,0,0,41,1681,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,41 +17 1852 . G <*> 0 . DP=1;I16=0,1,0,0,36,1296,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,36 +17 1853 . G <*> 0 . DP=1;I16=0,1,0,0,38,1444,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,38 +17 1854 . A <*> 0 . DP=1;I16=0,1,0,0,38,1444,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,38 +17 1855 . C <*> 0 . DP=1;I16=0,1,0,0,37,1369,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,37 +17 1856 . A <*> 0 . DP=1;I16=0,1,0,0,41,1681,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,41 +17 1857 . G <*> 0 . DP=1;I16=0,1,0,0,35,1225,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,35 +17 1858 . T <*> 0 . DP=1;I16=0,1,0,0,37,1369,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,37 +17 1859 . G <*> 0 . DP=1;I16=0,1,0,0,36,1296,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,36 +17 1860 . G <*> 0 . DP=1;I16=0,1,0,0,33,1089,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,33 +17 1861 . T <*> 0 . DP=1;I16=0,1,0,0,39,1521,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,39 +17 1862 . C <*> 0 . DP=1;I16=0,1,0,0,34,1156,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,34 +17 1863 . C <*> 0 . DP=1;I16=0,1,0,0,36,1296,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,36 +17 1864 . T <*> 0 . DP=1;I16=0,1,0,0,37,1369,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,37 +17 1865 . G <*> 0 . DP=1;I16=0,1,0,0,38,1444,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,38 +17 1866 . G <*> 0 . DP=1;I16=0,1,0,0,36,1296,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,36 +17 1867 . C <*> 0 . DP=1;I16=0,1,0,0,38,1444,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,38 +17 1868 . C <*> 0 . DP=1;I16=0,1,0,0,41,1681,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,41 +17 1869 . A T,<*> 0 . DP=1;I16=0,0,0,1,0,0,42,1764,0,0,60,3600,0,0,25,625;QS=0,1,0;SGB=-0.379885;MQ0F=0 PL 42,3,0,42,3,42 +17 1870 . C <*> 0 . DP=1;I16=0,1,0,0,36,1296,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,36 +17 1871 . C <*> 0 . DP=1;I16=0,1,0,0,29,841,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,29 +17 1872 . G <*> 0 . DP=1;I16=0,1,0,0,43,1849,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,43 +17 1873 . G <*> 0 . DP=1;I16=0,1,0,0,43,1849,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,43 +17 1874 . G <*> 0 . DP=1;I16=0,1,0,0,43,1849,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,43 +17 1875 . G <*> 0 . DP=1;I16=0,1,0,0,42,1764,0,0,60,3600,0,0,24,576,0,0;QS=1,0;MQ0F=0 PL 0,3,42 +17 1876 . C <*> 0 . DP=1;I16=0,1,0,0,41,1681,0,0,60,3600,0,0,23,529,0,0;QS=1,0;MQ0F=0 PL 0,3,41 +17 1877 . T <*> 0 . DP=1;I16=0,1,0,0,42,1764,0,0,60,3600,0,0,22,484,0,0;QS=1,0;MQ0F=0 PL 0,3,42 +17 1878 . C <*> 0 . DP=1;I16=0,1,0,0,40,1600,0,0,60,3600,0,0,21,441,0,0;QS=1,0;MQ0F=0 PL 0,3,40 +17 1879 . A <*> 0 . DP=1;I16=0,1,0,0,40,1600,0,0,60,3600,0,0,20,400,0,0;QS=1,0;MQ0F=0 PL 0,3,40 +17 1880 . C <*> 0 . DP=1;I16=0,1,0,0,31,961,0,0,60,3600,0,0,19,361,0,0;QS=1,0;MQ0F=0 PL 0,3,31 +17 1881 . G <*> 0 . DP=1;I16=0,1,0,0,42,1764,0,0,60,3600,0,0,18,324,0,0;QS=1,0;MQ0F=0 PL 0,3,42 +17 1882 . G <*> 0 . DP=1;I16=0,1,0,0,42,1764,0,0,60,3600,0,0,17,289,0,0;QS=1,0;MQ0F=0 PL 0,3,42 +17 1883 . A <*> 0 . DP=1;I16=0,1,0,0,43,1849,0,0,60,3600,0,0,16,256,0,0;QS=1,0;MQ0F=0 PL 0,3,43 +17 1884 . G <*> 0 . DP=1;I16=0,1,0,0,42,1764,0,0,60,3600,0,0,15,225,0,0;QS=1,0;MQ0F=0 PL 0,3,42 +17 1885 . C <*> 0 . DP=1;I16=0,1,0,0,42,1764,0,0,60,3600,0,0,14,196,0,0;QS=1,0;MQ0F=0 PL 0,3,42 +17 1886 . C <*> 0 . DP=1;I16=0,1,0,0,32,1024,0,0,60,3600,0,0,13,169,0,0;QS=1,0;MQ0F=0 PL 0,3,32 +17 1887 . G <*> 0 . DP=1;I16=0,1,0,0,40,1600,0,0,60,3600,0,0,12,144,0,0;QS=1,0;MQ0F=0 PL 0,3,40 +17 1888 . C <*> 0 . DP=1;I16=0,1,0,0,39,1521,0,0,60,3600,0,0,11,121,0,0;QS=1,0;MQ0F=0 PL 0,3,39 +17 1889 . C <*> 0 . DP=1;I16=0,1,0,0,37,1369,0,0,60,3600,0,0,10,100,0,0;QS=1,0;MQ0F=0 PL 0,3,37 +17 1890 . C <*> 0 . DP=1;I16=0,1,0,0,40,1600,0,0,60,3600,0,0,9,81,0,0;QS=1,0;MQ0F=0 PL 0,3,40 +17 1891 . T <*> 0 . DP=1;I16=0,1,0,0,39,1521,0,0,60,3600,0,0,8,64,0,0;QS=1,0;MQ0F=0 PL 0,3,39 +17 1892 . G <*> 0 . DP=1;I16=0,1,0,0,37,1369,0,0,60,3600,0,0,7,49,0,0;QS=1,0;MQ0F=0 PL 0,3,37 +17 1893 . T <*> 0 . DP=2;I16=1,1,0,0,72,2610,0,0,120,7200,0,0,6,36,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,72 +17 1894 . G <*> 0 . DP=2;I16=1,1,0,0,75,2817,0,0,120,7200,0,0,6,26,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,75 +17 1895 . C <*> 0 . DP=2;I16=1,1,0,0,73,2665,0,0,120,7200,0,0,6,20,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,73 +17 1896 . C <*> 0 . DP=2;I16=1,1,0,0,72,2600,0,0,120,7200,0,0,6,18,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,72 +17 1897 . G <*> 0 . DP=2;I16=1,0,0,0,27,729,0,0,60,3600,0,0,4,16,0,0;QS=1,0;MQ0F=0 PL 0,3,27 +17 1898 . T <*> 0 . DP=3;I16=2,0,0,0,67,2269,0,0,120,7200,0,0,5,25,0,0;QS=1,0;MQ0F=0 PL 0,6,62 +17 1899 . G <*> 0 . DP=3;I16=2,0,0,0,67,2245,0,0,120,7200,0,0,7,37,0,0;QS=1,0;MQ0F=0 PL 0,6,61 +17 1900 . T <*> 0 . DP=2;I16=2,0,0,0,76,2890,0,0,120,7200,0,0,9,53,0,0;QS=1,0;MQ0F=0 PL 0,6,69 +17 1901 . A <*> 0 . DP=2;I16=2,0,0,0,74,2740,0,0,120,7200,0,0,11,73,0,0;QS=1,0;MQ0F=0 PL 0,6,68 +17 1902 . C <*> 0 . DP=2;I16=2,0,0,0,66,2186,0,0,120,7200,0,0,13,97,0,0;QS=1,0;MQ0F=0 PL 0,6,60 +17 1903 . C <*> 0 . DP=2;I16=2,0,0,0,69,2393,0,0,120,7200,0,0,15,125,0,0;QS=1,0;MQ0F=0 PL 0,6,63 +17 1904 . T <*> 0 . DP=2;I16=2,0,0,0,84,3530,0,0,120,7200,0,0,17,157,0,0;QS=1,0;MQ0F=0 PL 0,6,77 +17 1905 . C <*> 0 . DP=2;I16=2,0,0,0,76,2888,0,0,120,7200,0,0,19,193,0,0;QS=1,0;MQ0F=0 PL 0,6,69 +17 1906 . T <*> 0 . DP=2;I16=2,0,0,0,82,3364,0,0,120,7200,0,0,21,233,0,0;QS=1,0;MQ0F=0 PL 0,6,75 +17 1907 . G <*> 0 . DP=2;I16=2,0,0,0,75,2813,0,0,120,7200,0,0,23,277,0,0;QS=1,0;MQ0F=0 PL 0,6,68 +17 1908 . A <*> 0 . DP=2;I16=2,0,0,0,73,2669,0,0,120,7200,0,0,25,325,0,0;QS=1,0;MQ0F=0 PL 0,6,67 +17 1909 . G <*> 0 . DP=2;I16=2,0,0,0,80,3202,0,0,120,7200,0,0,27,377,0,0;QS=1,0;MQ0F=0 PL 0,6,73 +17 1910 . C <*> 0 . DP=2;I16=2,0,0,0,78,3044,0,0,120,7200,0,0,29,433,0,0;QS=1,0;MQ0F=0 PL 0,6,71 +17 1911 . C <*> 0 . DP=2;I16=2,0,0,0,78,3044,0,0,120,7200,0,0,31,493,0,0;QS=1,0;MQ0F=0 PL 0,6,71 +17 1912 . C <*> 0 . DP=2;I16=2,0,0,0,80,3202,0,0,120,7200,0,0,33,557,0,0;QS=1,0;MQ0F=0 PL 0,6,73 +17 1913 . T <*> 0 . DP=2;I16=2,0,0,0,84,3528,0,0,120,7200,0,0,35,625,0,0;QS=1,0;MQ0F=0 PL 0,6,77 +17 1914 . C <*> 0 . DP=2;I16=2,0,0,0,82,3362,0,0,120,7200,0,0,37,697,0,0;QS=1,0;MQ0F=0 PL 0,6,75 +17 1915 . T <*> 0 . DP=2;I16=2,0,0,0,64,2210,0,0,120,7200,0,0,39,773,0,0;QS=1,0;MQ0F=0 PL 0,6,60 +17 1916 . G <*> 0 . DP=2;I16=2,0,0,0,75,2825,0,0,120,7200,0,0,41,853,0,0;QS=1,0;MQ0F=0 PL 0,6,69 +17 1917 . C <*> 0 . DP=2;I16=2,0,0,0,80,3202,0,0,120,7200,0,0,43,937,0,0;QS=1,0;MQ0F=0 PL 0,6,73 +17 1918 . A <*> 0 . DP=2;I16=2,0,0,0,79,3121,0,0,120,7200,0,0,45,1025,0,0;QS=1,0;MQ0F=0 PL 0,6,72 +17 1919 . C <*> 0 . DP=2;I16=2,0,0,0,79,3121,0,0,120,7200,0,0,46,1066,0,0;QS=1,0;MQ0F=0 PL 0,6,72 +17 1920 . A <*> 0 . DP=4;I16=2,1,0,0,107,3931,0,0,149,8041,0,0,47,1109,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,101 +17 1921 . G <*> 0 . DP=4;I16=2,2,0,0,146,5394,0,0,209,11641,0,0,57,1219,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,12,132 +17 1922 . T <*> 0 . DP=4;I16=2,2,0,0,152,5794,0,0,209,11641,0,0,60,1286,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,12,134 +17 1923 . G <*> 0 . DP=4;I16=2,2,0,0,145,5317,0,0,209,11641,0,0,63,1359,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,12,126 +17 1924 . C <*> 0 . DP=4;I16=2,2,0,0,127,4341,0,0,209,11641,0,0,65,1387,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,12,116 +17 1925 . C <*> 0 . DP=4;I16=2,2,0,0,135,4869,0,0,209,11641,0,0,67,1419,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,12,124 +17 1926 . T <*> 0 . DP=4;I16=2,2,0,0,160,6442,0,0,209,11641,0,0,69,1455,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,12,141 +17 1927 . T <*> 0 . DP=4;I16=2,2,0,0,157,6179,0,0,209,11641,0,0,71,1495,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,12,133 +17 1928 . C <*> 0 . DP=4;I16=2,2,0,0,146,5438,0,0,209,11641,0,0,73,1539,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,12,125 +17 1929 . T <*> 0 . DP=4;I16=2,2,0,0,161,6525,0,0,209,11641,0,0,75,1587,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,12,139 +17 1930 . G <*> 0 . DP=4;I16=2,1,0,0,114,4334,0,0,149,8041,0,0,60,1350,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,99 +17 1931 . C <*> 0 . DP=4;I16=2,2,0,0,132,4686,0,0,209,11641,0,0,79,1695,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,12,121 +17 1932 . T <*> 0 . DP=5;I16=2,3,0,0,164,5972,0,0,269,15241,0,0,81,1755,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL 0,15,146 +17 1933 . T <*> 0 . DP=5;I16=2,3,0,0,186,6958,0,0,269,15241,0,0,84,1820,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL 0,15,158 +17 1934 . G <*> 0 . DP=5;I16=2,3,0,0,173,6191,0,0,269,15241,0,0,87,1891,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL 0,15,143 +17 1935 . C <*> 0 . DP=5;I16=2,3,0,0,179,6539,0,0,269,15241,0,0,90,1968,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL 0,15,154 +17 1936 . C <*> 0 . DP=5;I16=2,3,0,0,181,6735,0,0,269,15241,0,0,93,2051,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL 0,15,159 +17 1937 . T <*> 0 . DP=5;I16=2,3,0,0,195,7741,0,0,269,15241,0,0,96,2140,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL 0,15,170 +17 1938 . G <*> 0 . DP=5;I16=2,3,0,0,176,6536,0,0,269,15241,0,0,99,2235,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL 0,15,155 +17 1939 . T <*> 0 . DP=5;I16=2,2,0,0,158,6250,0,0,240,14400,0,0,82,1924,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,144 +17 1940 . G <*> 0 . DP=5;I16=2,3,0,0,177,6449,0,0,269,15241,0,0,103,2339,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL 0,15,155 +17 1941 . G <*> 0 . DP=5;I16=2,3,0,0,180,6620,0,0,269,15241,0,0,105,2397,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL 0,15,156 +17 1942 . C <*> 0 . DP=5;I16=2,2,0,0,152,5892,0,0,240,14400,0,0,85,1975,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,140 +17 1943 . T <*> 0 . DP=5;I16=2,3,0,0,202,8198,0,0,269,15241,0,0,109,2525,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL 0,15,167 +17 1944 . T <*> 0 . DP=5;I16=2,3,0,0,199,7983,0,0,269,15241,0,0,111,2595,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL 0,15,170 +17 1945 . T <*> 0 . DP=5;I16=2,3,0,0,200,8062,0,0,269,15241,0,0,113,2669,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL 0,15,171 +17 1946 . G <*> 0 . DP=5;I16=2,3,0,0,188,7132,0,0,269,15241,0,0,114,2696,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL 0,15,162 +17 1947 . A <*> 0 . DP=5;I16=2,3,0,0,181,6939,0,0,269,15241,0,0,115,2725,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL 0,15,160 +17 1948 . G C,<*> 0 . DP=5;I16=2,2,0,1,150,5708,16,256,240,14400,29,841,91,2131,25,625;QS=0.903614,0.0963855,0;SGB=-0.379885;RPB=1;MQB=1;MQSB=0.666667;BQB=1;MQ0F=0 PL 1,0,123,13,126,132 +17 1949 . A <*> 0 . DP=5;I16=2,3,0,0,181,6599,0,0,269,15241,0,0,117,2789,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL 0,15,155 +17 1950 . A <*> 0 . DP=6;I16=2,4,0,0,219,8167,0,0,329,18841,0,0,118,2824,0,0;QS=1,0;MQSB=0.75;MQ0F=0 PL 0,18,176 +17 1951 . G <*> 0 . DP=6;I16=2,4,0,0,225,8533,0,0,329,18841,0,0,120,2862,0,0;QS=1,0;MQSB=0.75;MQ0F=0 PL 0,18,181 +17 1952 . A <*> 0 . DP=6;I16=2,4,0,0,219,8221,0,0,329,18841,0,0,122,2904,0,0;QS=1,0;MQSB=0.75;MQ0F=0 PL 0,18,182 +17 1953 . A <*> 0 . DP=6;I16=2,4,0,0,201,7161,0,0,329,18841,0,0,124,2950,0,0;QS=1,0;MQSB=0.75;MQ0F=0 PL 0,18,168 +17 1954 . A C,<*> 0 . DP=6;I16=2,3,0,1,166,5942,18,324,300,18000,29,841,101,2375,25,625;QS=0.902174,0.0978261,0;SGB=-0.379885;RPB=1;MQB=1;MQSB=0.75;BQB=1;MQ0F=0 PL 0,0,130,15,133,141 +17 1955 . C <*> 0 . DP=6;I16=2,3,0,0,190,7232,0,0,300,18000,0,0,103,2429,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,165 +17 1956 . C <*> 0 . DP=6;I16=2,3,0,0,189,7211,0,0,300,18000,0,0,105,2487,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,164 +17 1957 . C <*> 0 . DP=6;I16=2,3,0,0,192,7426,0,0,300,18000,0,0,107,2549,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,167 +17 1958 . C <*> 0 . DP=6;I16=2,4,0,0,234,9220,0,0,329,18841,0,0,133,3189,0,0;QS=1,0;MQSB=0.75;MQ0F=0 PL 0,18,190 +17 1959 . T <*> 0 . DP=6;I16=2,4,0,0,233,9255,0,0,329,18841,0,0,134,3206,0,0;QS=1,0;MQSB=0.75;MQ0F=0 PL 0,18,193 +17 1960 . T <*> 0 . DP=6;I16=2,4,0,0,227,8703,0,0,329,18841,0,0,135,3225,0,0;QS=1,0;MQSB=0.75;MQ0F=0 PL 0,18,186 +17 1961 . C <*> 0 . DP=6;I16=2,4,0,0,219,8327,0,0,329,18841,0,0,136,3246,0,0;QS=1,0;MQSB=0.75;MQ0F=0 PL 0,18,183 +17 1962 . T <*> 0 . DP=6;I16=2,4,0,0,248,10276,0,0,329,18841,0,0,137,3269,0,0;QS=1,0;MQSB=0.75;MQ0F=0 PL 0,18,198 +17 1963 . G <*> 0 . DP=6;I16=2,4,0,0,229,8867,0,0,329,18841,0,0,138,3294,0,0;QS=1,0;MQSB=0.75;MQ0F=0 PL 0,18,188 +17 1964 . G <*> 0 . DP=6;I16=2,4,0,0,202,7200,0,0,329,18841,0,0,139,3321,0,0;QS=1,0;MQSB=0.75;MQ0F=0 PL 0,18,169 +17 1965 . T <*> 0 . DP=6;I16=2,4,0,0,203,7523,0,0,329,18841,0,0,140,3350,0,0;QS=1,0;MQSB=0.75;MQ0F=0 PL 0,18,171 +17 1966 . T <*> 0 . DP=6;I16=2,4,0,0,218,8218,0,0,329,18841,0,0,141,3381,0,0;QS=1,0;MQSB=0.75;MQ0F=0 PL 0,18,181 +17 1967 . A <*> 0 . DP=6;I16=2,4,0,0,232,9056,0,0,329,18841,0,0,142,3414,0,0;QS=1,0;MQSB=0.75;MQ0F=0 PL 0,18,182 +17 1968 . T <*> 0 . DP=6;I16=2,4,0,0,242,9786,0,0,329,18841,0,0,143,3449,0,0;QS=1,0;MQSB=0.75;MQ0F=0 PL 0,18,190 +17 1969 . A <*> 0 . DP=6;I16=2,4,0,0,235,9247,0,0,329,18841,0,0,143,3437,0,0;QS=1,0;MQSB=0.75;MQ0F=0 PL 0,18,186 +17 1970 . C <*> 0 . DP=6;I16=2,4,0,0,220,8160,0,0,329,18841,0,0,143,3429,0,0;QS=1,0;MQSB=0.75;MQ0F=0 PL 0,18,180 +17 1971 . A <*> 0 . DP=7;I16=2,5,0,0,272,10634,0,0,389,22441,0,0,143,3425,0,0;QS=1,0;MQSB=0.8;MQ0F=0 PL 0,21,206 +17 1972 . T <*> 0 . DP=7;I16=2,5,0,0,260,9924,0,0,389,22441,0,0,144,3426,0,0;QS=1,0;MQSB=0.8;MQ0F=0 PL 0,21,203 +17 1973 . A <*> 0 . DP=7;I16=2,4,0,0,240,9646,0,0,360,21600,0,0,120,2808,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,196 +17 1974 . A <*> 0 . DP=7;I16=2,5,0,0,278,11178,0,0,389,22441,0,0,145,3397,0,0;QS=1,0;MQSB=0.8;MQ0F=0 PL 0,21,214 +17 1975 . G <*> 0 . DP=7;I16=2,5,0,0,256,9422,0,0,389,22441,0,0,145,3369,0,0;QS=1,0;MQSB=0.8;MQ0F=0 PL 0,21,195 +17 1976 . A <*> 0 . DP=7;I16=2,5,0,0,261,9849,0,0,389,22441,0,0,144,3298,0,0;QS=1,0;MQSB=0.8;MQ0F=0 PL 0,21,199 +17 1977 . C <*> 0 . DP=7;I16=2,5,0,0,253,9303,0,0,389,22441,0,0,143,3233,0,0;QS=1,0;MQSB=0.8;MQ0F=0 PL 0,21,194 +17 1978 . A <*> 0 . DP=7;I16=2,5,0,0,294,12372,0,0,389,22441,0,0,142,3174,0,0;QS=1,0;MQSB=0.8;MQ0F=0 PL 0,21,220 +17 1979 . G <*> 0 . DP=7;I16=2,5,0,0,278,11068,0,0,389,22441,0,0,141,3121,0,0;QS=1,0;MQSB=0.8;MQ0F=0 PL 0,21,208 +17 1980 . C <*> 0 . DP=7;I16=2,5,0,0,254,9370,0,0,389,22441,0,0,140,3074,0,0;QS=1,0;MQSB=0.8;MQ0F=0 PL 0,21,197 +17 1981 . C <*> 0 . DP=8;I16=3,5,0,0,290,10896,0,0,449,26041,0,0,139,3033,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,219 +17 1982 . A <*> 0 . DP=9;I16=4,5,0,0,342,13268,0,0,509,29641,0,0,139,2999,0,0;QS=1,0;MQSB=0.89338;MQ0F=0 PL 0,27,254 +17 1983 . G <*> 0 . DP=9;I16=4,5,0,0,337,12781,0,0,509,29641,0,0,140,2974,0,0;QS=1,0;MQSB=0.89338;MQ0F=0 PL 0,27,249 +17 1984 . A <*> 0 . DP=9;I16=4,5,0,0,355,14231,0,0,509,29641,0,0,141,2959,0,0;QS=1,0;MQSB=0.89338;MQ0F=0 PL 0,27,255 +17 1985 . G <*> 0 . DP=9;I16=4,5,0,0,307,10921,0,0,509,29641,0,0,142,2954,0,0;QS=1,0;MQSB=0.89338;MQ0F=0 PL 0,27,231 +17 1986 . A <*> 0 . DP=9;I16=4,4,0,0,287,10695,0,0,480,28800,0,0,118,2334,0,0;QS=1,0;MQSB=0.992367;MQ0F=0 PL 0,24,223 +17 1987 . A <*> 0 . DP=9;I16=4,5,0,0,333,12731,0,0,509,29641,0,0,144,2974,0,0;QS=1,0;MQSB=0.89338;MQ0F=0 PL 0,27,247 +17 1988 . G <*> 0 . DP=9;I16=4,5,0,0,324,12106,0,0,509,29641,0,0,145,2999,0,0;QS=1,0;MQSB=0.89338;MQ0F=0 PL 0,27,239 +17 1989 . G <*> 0 . DP=9;I16=4,5,0,0,322,12030,0,0,509,29641,0,0,145,2985,0,0;QS=1,0;MQSB=0.89338;MQ0F=0 PL 0,27,237 +17 1990 . G T,<*> 0 . DP=9;I16=4,4,0,1,282,10212,33,1089,480,28800,29,841,120,2358,25,625;QS=0.906752,0.0932476,0;SGB=-0.379885;RPB=1;MQB=1;MQSB=0.89338;BQB=1;MQ0F=0 PL 2,0,195,26,198,215 +17 1991 . A <*> 0 . DP=9;I16=4,5,0,0,335,13049,0,0,509,29641,0,0,145,2993,0,0;QS=1,0;MQSB=0.89338;MQ0F=0 PL 0,27,250 +17 1992 . G <*> 0 . DP=9;I16=4,5,0,0,307,11009,0,0,509,29641,0,0,145,3015,0,0;QS=1,0;MQSB=0.89338;MQ0F=0 PL 0,27,231 +17 1993 . T <*> 0 . DP=9;I16=4,5,0,0,336,12804,0,0,509,29641,0,0,145,3049,0,0;QS=1,0;MQSB=0.89338;MQ0F=0 PL 0,27,243 +17 1994 . T <*> 0 . DP=8;I16=3,5,0,0,282,10256,0,0,449,26041,0,0,146,3094,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,216 +17 1995 . G <*> 0 . DP=8;I16=3,4,0,0,232,8118,0,0,420,25200,0,0,122,2524,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,188 +17 1996 . C <*> 0 . DP=8;I16=3,5,0,0,247,8121,0,0,449,26041,0,0,147,3165,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,192 +17 1997 . C <*> 0 . DP=8;I16=3,5,0,0,248,8200,0,0,449,26041,0,0,146,3142,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,193 +17 1998 . C <*> 0 . DP=8;I16=3,5,0,0,289,10699,0,0,449,26041,0,0,145,3129,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,222 +17 1999 . A <*> 0 . DP=7;I16=2,5,0,0,276,11074,0,0,389,22441,0,0,145,3125,0,0;QS=1,0;MQSB=0.8;MQ0F=0 PL 0,21,206 +17 2000 . G <*> 0 . DP=7;I16=1,5,0,0,226,8690,0,0,329,18841,0,0,127,2805,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,168 +17 2001 . G <*> 0 . DP=7;I16=1,5,0,0,222,8458,0,0,329,18841,0,0,126,2780,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,172 +17 2002 . G <*> 0 . DP=7;I16=2,4,0,0,197,7073,0,0,360,21600,0,0,127,2837,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,163 +17 2003 . T <*> 0 . DP=7;I16=2,5,0,0,242,8784,0,0,389,22441,0,0,145,3189,0,0;QS=1,0;MQSB=0.8;MQ0F=0 PL 0,21,190 +17 2004 . G <*> 0 . DP=7;I16=2,4,0,0,216,8092,0,0,360,21600,0,0,129,2969,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,178 +17 2005 . G <*> 0 . DP=7;I16=2,4,0,0,190,6882,0,0,360,21600,0,0,130,3044,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,153 +17 2006 . C <*> 0 . DP=7;I16=2,4,0,0,204,7404,0,0,360,21600,0,0,131,3125,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,166 +17 2007 . A <*> 0 . DP=7;I16=2,5,0,0,249,9041,0,0,389,22441,0,0,144,3330,0,0;QS=1,0;MQSB=0.8;MQ0F=0 PL 0,21,193 +17 2008 . C <*> 0 . DP=7;I16=2,5,0,0,232,8210,0,0,389,22441,0,0,141,3245,0,0;QS=1,0;MQSB=0.8;MQ0F=0 PL 0,21,183 +17 2009 . A <*> 0 . DP=7;I16=2,5,0,0,266,10628,0,0,389,22441,0,0,138,3166,0,0;QS=1,0;MQSB=0.8;MQ0F=0 PL 0,21,210 +17 2010 . G <*> 0 . DP=7;I16=2,4,0,0,204,7382,0,0,360,21600,0,0,125,2993,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,169 +17 2011 . C <*> 0 . DP=7;I16=2,4,0,0,211,7627,0,0,360,21600,0,0,123,2945,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,175 +17 2012 . A <*> 0 . DP=7;I16=2,5,0,0,239,8743,0,0,389,22441,0,0,129,2965,0,0;QS=1,0;MQSB=0.8;MQ0F=0 PL 0,21,189 +17 2013 . C <*> 0 . DP=7;I16=2,4,0,0,197,6509,0,0,360,21600,0,0,119,2861,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,160 +17 2014 . G <*> 0 . DP=6;I16=2,4,0,0,195,6881,0,0,329,18841,0,0,124,2860,0,0;QS=1,0;MQSB=0.75;MQ0F=0 PL 0,18,160 +17 2015 . T <*> 0 . DP=6;I16=2,4,0,0,221,8381,0,0,329,18841,0,0,122,2814,0,0;QS=1,0;MQSB=0.75;MQ0F=0 PL 0,18,178 +17 2016 . T <*> 0 . DP=6;I16=2,4,0,0,222,8338,0,0,329,18841,0,0,120,2772,0,0;QS=1,0;MQSB=0.75;MQ0F=0 PL 0,18,178 +17 2017 . G <*> 0 . DP=6;I16=2,4,0,0,215,7999,0,0,329,18841,0,0,118,2734,0,0;QS=1,0;MQSB=0.75;MQ0F=0 PL 0,18,172 +17 2018 . C <*> 0 . DP=6;I16=2,4,0,0,202,7480,0,0,329,18841,0,0,116,2700,0,0;QS=1,0;MQSB=0.75;MQ0F=0 PL 0,18,169 +17 2019 . T <*> 0 . DP=6;I16=2,4,0,0,233,9103,0,0,329,18841,0,0,114,2670,0,0;QS=1,0;MQSB=0.75;MQ0F=0 PL 0,18,187 +17 2020 . G <*> 0 . DP=6;I16=2,4,0,0,212,7790,0,0,329,18841,0,0,112,2644,0,0;QS=1,0;MQSB=0.75;MQ0F=0 PL 0,18,175 +17 2021 . C <*> 0 . DP=5;I16=2,3,0,0,192,7432,0,0,300,18000,0,0,111,2621,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,167 +17 2022 . C <*> 0 . DP=6;I16=3,3,0,0,210,7490,0,0,360,21600,0,0,110,2600,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,177 +17 2023 . A <*> 0 . DP=6;I16=3,3,0,0,221,8457,0,0,360,21600,0,0,110,2582,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,186 +17 2024 . G <*> 0 . DP=8;I16=4,4,0,0,258,8728,0,0,480,28800,0,0,110,2568,0,0;QS=1,0;MQSB=0.992367;MQ0F=0 PL 0,24,203 +17 2025 . T <*> 0 . DP=8;I16=4,4,0,0,290,10752,0,0,480,28800,0,0,112,2560,0,0;QS=1,0;MQSB=0.992367;MQ0F=0 PL 0,24,226 +17 2026 . T <*> 0 . DP=8;I16=4,4,0,0,267,9287,0,0,480,28800,0,0,113,2511,0,0;QS=1,0;MQSB=0.992367;MQ0F=0 PL 0,24,208 +17 2027 . A <*> 0 . DP=8;I16=3,4,0,0,258,9550,0,0,420,25200,0,0,89,1847,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,207 +17 2028 . C <*> 0 . DP=8;I16=4,4,0,0,293,10887,0,0,480,28800,0,0,115,2443,0,0;QS=1,0;MQSB=0.992367;MQ0F=0 PL 0,24,228 +17 2029 . T <*> 0 . DP=8;I16=4,4,0,0,306,11824,0,0,480,28800,0,0,116,2424,0,0;QS=1,0;MQSB=0.992367;MQ0F=0 PL 0,24,236 +17 2030 . G <*> 0 . DP=8;I16=4,4,0,0,278,9842,0,0,480,28800,0,0,117,2415,0,0;QS=1,0;MQSB=0.992367;MQ0F=0 PL 0,24,216 +17 2031 . C <*> 0 . DP=8;I16=4,4,0,0,262,8824,0,0,480,28800,0,0,118,2416,0,0;QS=1,0;MQSB=0.992367;MQ0F=0 PL 0,24,204 +17 2032 . C <*> 0 . DP=8;I16=4,4,0,0,268,9364,0,0,480,28800,0,0,119,2427,0,0;QS=1,0;MQSB=0.992367;MQ0F=0 PL 0,24,210 +17 2033 . A <*> 0 . DP=7;I16=4,3,0,0,254,9280,0,0,420,25200,0,0,121,2447,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,203 +17 2034 . T <*> 0 . DP=7;I16=4,3,0,0,257,9659,0,0,420,25200,0,0,123,2475,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,208 +17 2035 . T <*> 0 . DP=7;I16=4,3,0,0,260,10046,0,0,420,25200,0,0,125,2511,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,211 +17 2036 . T <*> 0 . DP=7;I16=4,3,0,0,268,10428,0,0,420,25200,0,0,127,2555,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,216 +17 2037 . T <*> 0 . DP=7;I16=4,3,0,0,271,10557,0,0,420,25200,0,0,129,2607,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,217 +17 2038 . C <*> 0 . DP=7;I16=4,3,0,0,262,9910,0,0,420,25200,0,0,131,2667,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,211 +17 2039 . A <*> 0 . DP=7;I16=4,3,0,0,265,10071,0,0,420,25200,0,0,133,2735,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,212 +17 2040 . C <*> 0 . DP=7;I16=4,3,0,0,243,8635,0,0,420,25200,0,0,135,2811,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,196 +17 2041 . G A,<*> 0 . DP=7;I16=0,0,4,3,0,0,276,11066,0,0,420,25200,0,0,137,2895;QS=0,1,0;VDB=0.80233;SGB=-0.636426;MQSB=1.01283;MQ0F=0 PL 223,21,0,223,21,223 +17 2042 . G <*> 0 . DP=7;I16=4,3,0,0,256,9542,0,0,420,25200,0,0,139,2987,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,206 +17 2043 . G <*> 0 . DP=7;I16=4,3,0,0,240,8782,0,0,420,25200,0,0,141,3087,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,197 +17 2044 . C <*> 0 . DP=7;I16=4,3,0,0,258,9636,0,0,420,25200,0,0,143,3195,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,207 +17 2045 . A <*> 0 . DP=7;I16=4,3,0,0,267,10223,0,0,420,25200,0,0,145,3311,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,213 +17 2046 . T <*> 0 . DP=7;I16=4,3,0,0,272,10582,0,0,420,25200,0,0,147,3435,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,216 +17 2047 . G <*> 0 . DP=7;I16=3,3,0,0,234,9142,0,0,360,21600,0,0,123,2893,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,195 +17 2048 . A <*> 0 . DP=7;I16=4,3,0,0,255,9513,0,0,420,25200,0,0,148,3560,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,206 +17 2049 . A <*> 0 . DP=7;I16=4,3,0,0,261,9777,0,0,420,25200,0,0,148,3610,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,208 +17 2050 . A <*> 0 . DP=7;I16=3,3,0,0,223,8391,0,0,360,21600,0,0,121,2941,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,188 +17 2051 . T <*> 0 . DP=6;I16=4,2,0,0,204,7382,0,0,360,21600,0,0,145,3525,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,170 +17 2052 . G <*> 0 . DP=6;I16=4,2,0,0,211,7615,0,0,360,21600,0,0,144,3486,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,175 +17 2053 . G <*> 0 . DP=6;I16=4,2,0,0,219,8091,0,0,360,21600,0,0,143,3449,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,180 +17 2054 . A <*> 0 . DP=6;I16=4,2,0,0,203,7377,0,0,360,21600,0,0,142,3414,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,171 +17 2055 . G <*> 0 . DP=6;I16=4,2,0,0,203,7071,0,0,360,21600,0,0,141,3381,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,168 +17 2056 . A <*> 0 . DP=6;I16=4,2,0,0,219,8059,0,0,360,21600,0,0,140,3350,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,179 +17 2057 . T <*> 0 . DP=6;I16=4,2,0,0,219,8015,0,0,360,21600,0,0,138,3272,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,178 +17 2058 . A <*> 0 . DP=6;I16=4,2,0,0,217,7929,0,0,360,21600,0,0,135,3149,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,179 +17 2059 . A <*> 0 . DP=6;I16=4,2,0,0,230,8866,0,0,360,21600,0,0,132,3032,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,188 +17 2060 . C <*> 0 . DP=6;I16=3,2,0,0,162,5622,0,0,300,18000,0,0,107,2437,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,143 +17 2061 . A <*> 0 . DP=5;I16=3,2,0,0,187,7029,0,0,300,18000,0,0,105,2375,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,163 +17 2062 . A <*> 0 . DP=5;I16=3,2,0,0,187,7195,0,0,300,18000,0,0,103,2317,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,164 +17 2063 . C <*> 0 . DP=5;I16=3,2,0,0,182,6678,0,0,300,18000,0,0,101,2263,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,158 +17 2064 . A <*> 0 . DP=5;I16=3,2,0,0,188,7154,0,0,300,18000,0,0,99,2213,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,164 +17 2065 . G <*> 0 . DP=6;I16=4,2,0,0,204,7038,0,0,360,21600,0,0,97,2167,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,167 +17 2066 . G <*> 0 . DP=6;I16=4,2,0,0,184,5774,0,0,360,21600,0,0,96,2126,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,152 +17 2067 . A <*> 0 . DP=6;I16=4,2,0,0,228,8744,0,0,360,21600,0,0,95,2091,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,187 +17 2068 . G <*> 0 . DP=6;I16=4,2,0,0,201,7049,0,0,360,21600,0,0,94,2062,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,167 +17 2069 . C <*> 0 . DP=6;I16=4,2,0,0,191,6207,0,0,360,21600,0,0,93,2039,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,156 +17 2070 . G <*> 0 . DP=6;I16=4,2,0,0,178,5370,0,0,360,21600,0,0,92,2022,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,145 +17 2071 . A <*> 0 . DP=6;I16=4,2,0,0,216,7856,0,0,360,21600,0,0,91,2011,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,177 +17 2072 . C <*> 0 . DP=5;I16=4,1,0,0,157,4971,0,0,300,18000,0,0,91,2005,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,128 +17 2073 . C <*> 0 . DP=5;I16=4,1,0,0,161,5287,0,0,300,18000,0,0,91,2003,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,133 +17 2074 . G <*> 0 . DP=5;I16=3,1,0,0,94,2330,0,0,240,14400,0,0,66,1380,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,83 +17 2075 . C <*> 0 . DP=5;I16=4,1,0,0,140,4038,0,0,300,18000,0,0,91,2011,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,115 +17 2076 . A <*> 0 . DP=5;I16=3,1,0,0,130,4242,0,0,240,14400,0,0,80,1900,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,114 +17 2077 . C <*> 0 . DP=5;I16=4,1,0,0,150,4766,0,0,300,18000,0,0,91,2035,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,125 +17 2078 . A <*> 0 . DP=5;I16=4,1,0,0,180,6606,0,0,300,18000,0,0,91,2053,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,148 +17 2079 . G <*> 0 . DP=5;I16=4,1,0,0,160,5324,0,0,300,18000,0,0,91,2075,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,133 +17 2080 . G <*> 0 . DP=5;I16=3,1,0,0,121,3819,0,0,240,14400,0,0,76,1876,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,108 +17 2081 . C <*> 0 . DP=5;I16=4,1,0,0,132,3710,0,0,300,18000,0,0,91,2131,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,110 +17 2082 . T <*> 0 . DP=4;I16=3,1,0,0,125,4087,0,0,240,14400,0,0,92,2164,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,112 +17 2083 . G <*> 0 . DP=4;I16=3,1,0,0,127,4195,0,0,240,14400,0,0,93,2199,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,113 +17 2084 . C <*> 0 . DP=4;I16=3,1,0,0,131,4365,0,0,240,14400,0,0,94,2236,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,115 +17 2085 . T <*> 0 . DP=4;I16=3,1,0,0,147,5477,0,0,240,14400,0,0,95,2275,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,130 +17 2086 . G <*> 0 . DP=4;I16=3,1,0,0,147,5449,0,0,240,14400,0,0,96,2316,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,129 +17 2087 . A <*> 0 . DP=4;I16=3,1,0,0,143,5207,0,0,240,14400,0,0,97,2359,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,126 +17 2088 . G <*> 0 . DP=4;I16=3,1,0,0,137,4767,0,0,240,14400,0,0,98,2404,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,121 +17 2089 . C <*> 0 . DP=5;I16=4,1,0,0,168,5664,0,0,300,18000,0,0,99,2451,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,138 +17 2090 . G <*> 0 . DP=5;I16=3,1,0,0,112,3294,0,0,240,14400,0,0,76,1876,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,99 +17 2091 . C <*> 0 . DP=5;I16=4,1,0,0,152,4822,0,0,300,18000,0,0,102,2504,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,125 +17 2092 . G <*> 0 . DP=6;I16=5,1,0,0,172,5180,0,0,360,21600,0,0,103,2509,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,133 +17 2093 . T <*> 0 . DP=6;I16=5,1,0,0,195,6697,0,0,360,21600,0,0,105,2517,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,153 +17 2094 . C <*> 0 . DP=6;I16=5,1,0,0,185,5827,0,0,360,21600,0,0,107,2529,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,142 +17 2095 . A <*> 0 . DP=6;I16=5,1,0,0,202,6892,0,0,360,21600,0,0,109,2545,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,154 +17 2096 . C <*> 0 . DP=6;I16=5,1,0,0,214,7660,0,0,360,21600,0,0,111,2565,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,161 +17 2097 . A <*> 0 . DP=6;I16=5,1,0,0,228,8686,0,0,360,21600,0,0,113,2589,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,172 +17 2098 . C <*> 0 . DP=6;I16=5,1,0,0,182,5678,0,0,360,21600,0,0,114,2568,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,139 +17 2099 . G <*> 0 . DP=6;I16=5,1,0,0,168,4910,0,0,360,21600,0,0,115,2553,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,129 +17 2100 . C <*> 0 . DP=6;I16=5,1,0,0,208,7382,0,0,360,21600,0,0,114,2446,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,160 +17 2101 . A <*> 0 . DP=6;I16=5,1,0,0,210,7502,0,0,360,21600,0,0,113,2349,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,161 +17 2102 . G <*> 0 . DP=6;I16=5,1,0,0,194,6610,0,0,360,21600,0,0,112,2262,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,151 +17 2103 . C <*> 0 . DP=6;I16=4,1,0,0,175,6367,0,0,300,18000,0,0,92,1824,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,146 +17 2104 . C <*> 0 . DP=5;I16=4,1,0,0,178,6450,0,0,300,18000,0,0,92,1794,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,147 +17 2105 . A <*> 0 . DP=5;I16=4,1,0,0,159,5155,0,0,300,18000,0,0,92,1772,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,130 +17 2106 . T <*> 0 . DP=5;I16=4,1,0,0,180,6500,0,0,300,18000,0,0,92,1758,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,146 +17 2107 . C <*> 0 . DP=5;I16=4,1,0,0,162,5414,0,0,300,18000,0,0,92,1752,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,133 +17 2108 . G <*> 0 . DP=5;I16=4,1,0,0,133,3807,0,0,300,18000,0,0,92,1754,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,111 +17 2109 . C <*> 0 . DP=5;I16=4,1,0,0,154,5166,0,0,300,18000,0,0,92,1764,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,125 +17 2110 . G <*> 0 . DP=5;I16=4,1,0,0,140,4176,0,0,300,18000,0,0,92,1782,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,117 +17 2111 . C <*> 0 . DP=5;I16=4,1,0,0,170,5932,0,0,300,18000,0,0,92,1808,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,140 +17 2112 . A <*> 0 . DP=5;I16=4,1,0,0,168,5954,0,0,300,18000,0,0,92,1842,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,140 +17 2113 . G <*> 0 . DP=5;I16=4,1,0,0,159,5407,0,0,300,18000,0,0,92,1884,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,134 +17 2114 . C <*> 0 . DP=5;I16=4,1,0,0,150,5014,0,0,300,18000,0,0,92,1934,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,126 +17 2115 . T <*> 0 . DP=5;I16=4,1,0,0,174,6196,0,0,300,18000,0,0,91,1941,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,143 +17 2116 . C <*> 0 . DP=5;I16=4,1,0,0,185,6931,0,0,300,18000,0,0,90,1954,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,152 +17 2117 . A <*> 0 . DP=5;I16=4,1,0,0,191,7373,0,0,300,18000,0,0,89,1973,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,156 +17 2118 . G <*> 0 . DP=5;I16=4,1,0,0,179,6497,0,0,300,18000,0,0,87,1947,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,147 +17 2119 . G <*> 0 . DP=5;I16=4,1,0,0,164,5642,0,0,300,18000,0,0,85,1925,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,137 +17 2120 . G <*> 0 . DP=5;I16=4,1,0,0,171,5947,0,0,300,18000,0,0,83,1907,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,140 +17 2121 . A <*> 0 . DP=5;I16=3,1,0,0,136,4870,0,0,240,14400,0,0,56,1268,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,122 +17 2122 . T <*> 0 . DP=5;I16=3,1,0,0,138,4922,0,0,240,14400,0,0,54,1258,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,123 +17 2123 . A <*> 0 . DP=5;I16=4,1,0,0,166,5692,0,0,300,18000,0,0,77,1877,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,137 +17 2124 . T <*> 0 . DP=5;I16=4,1,0,0,166,5612,0,0,300,18000,0,0,75,1875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,136 +17 2125 . T <*> 0 . DP=3;I16=3,0,0,0,110,4094,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,93 +17 2126 . A <*> 0 . DP=3;I16=3,0,0,0,113,4281,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,95 +17 2127 . C <*> 0 . DP=3;I16=3,0,0,0,113,4275,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,95 +17 2128 . G <*> 0 . DP=3;I16=3,0,0,0,84,2478,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,72 +17 2129 . T <*> 0 . DP=3;I16=3,0,0,0,98,3286,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,83 +17 2130 . G <*> 0 . DP=3;I16=3,0,0,0,101,3609,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,87 +17 2131 . T <*> 0 . DP=3;I16=3,0,0,0,91,3025,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,79 +17 2132 . A <*> 0 . DP=3;I16=3,0,0,0,104,3678,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,88 +17 2133 . A <*> 0 . DP=3;I16=3,0,0,0,113,4331,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,96 +17 2134 . C <*> 0 . DP=3;I16=3,0,0,0,102,3546,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQ0F=0 PL 0,9,86 +17 2135 . T <*> 0 . DP=4;I16=3,1,0,0,132,4682,0,0,240,14400,0,0,75,1875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,119 +17 2136 . C <*> 0 . DP=4;I16=3,1,0,0,144,5314,0,0,240,14400,0,0,76,1876,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,127 +17 2137 . G <*> 0 . DP=4;I16=3,1,0,0,114,3426,0,0,240,14400,0,0,77,1879,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,102 +17 2138 . A <*> 0 . DP=4;I16=3,1,0,0,159,6337,0,0,240,14400,0,0,78,1884,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,139 +17 2139 . C <*> 0 . DP=4;I16=3,1,0,0,143,5143,0,0,240,14400,0,0,79,1891,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,125 +17 2140 . A <*> 0 . DP=4;I16=3,1,0,0,157,6171,0,0,240,14400,0,0,80,1900,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,138 +17 2141 . T <*> 0 . DP=4;I16=3,1,0,0,156,6098,0,0,240,14400,0,0,80,1862,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,137 +17 2142 . G <*> 0 . DP=4;I16=3,1,0,0,145,5349,0,0,240,14400,0,0,80,1828,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,129 +17 2143 . T <*> 0 . DP=4;I16=3,1,0,0,134,4698,0,0,240,14400,0,0,80,1798,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,120 +17 2144 . C <*> 0 . DP=4;I16=3,1,0,0,141,5065,0,0,240,14400,0,0,80,1772,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,125 +17 2145 . A <*> 0 . DP=4;I16=3,1,0,0,158,6300,0,0,240,14400,0,0,80,1750,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,139 +17 2146 . G <*> 0 . DP=4;I16=3,1,0,0,144,5242,0,0,240,14400,0,0,80,1732,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,127 +17 2147 . C <*> 0 . DP=5;I16=3,1,0,0,148,5502,0,0,240,14400,0,0,80,1718,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,130 +17 2148 . G <*> 0 . DP=5;I16=2,2,0,0,131,4413,0,0,240,14400,0,0,66,1428,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,120 +17 2149 . A <*> 0 . DP=5;I16=2,2,0,0,138,4886,0,0,240,14400,0,0,68,1462,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,127 +17 2150 . T <*> 0 . DP=5;I16=3,2,0,0,157,5265,0,0,300,18000,0,0,85,1725,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,139 +17 2151 . T <*> 0 . DP=5;I16=3,2,0,0,163,5451,0,0,300,18000,0,0,86,1738,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,142 +17 2152 . G <*> 0 . DP=5;I16=3,2,0,0,168,5774,0,0,300,18000,0,0,87,1757,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,146 +17 2153 . T <*> 0 . DP=5;I16=3,2,0,0,186,7002,0,0,300,18000,0,0,88,1782,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,162 +17 2154 . C <*> 0 . DP=5;I16=3,2,0,0,183,6803,0,0,300,18000,0,0,89,1813,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,159 +17 2155 . A <*> 0 . DP=5;I16=3,2,0,0,179,6639,0,0,300,18000,0,0,90,1850,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,156 +17 2156 . C <*> 0 . DP=5;I16=3,2,0,0,177,6331,0,0,300,18000,0,0,91,1893,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,154 +17 2157 . A <*> 0 . DP=5;I16=3,2,0,0,199,7987,0,0,300,18000,0,0,92,1942,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,173 +17 2158 . G <*> 0 . DP=5;I16=3,2,0,0,163,5717,0,0,300,18000,0,0,93,1997,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,144 +17 2159 . G <*> 0 . DP=5;I16=3,2,0,0,174,6250,0,0,300,18000,0,0,94,2058,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,153 +17 2160 . C <*> 0 . DP=5;I16=3,2,0,0,177,6351,0,0,300,18000,0,0,95,2125,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,154 +17 2161 . A <*> 0 . DP=5;I16=3,2,0,0,189,7189,0,0,300,18000,0,0,95,2147,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,164 +17 2162 . C <*> 0 . DP=5;I16=3,2,0,0,179,6435,0,0,300,18000,0,0,95,2173,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,155 +17 2163 . T <*> 0 . DP=5;I16=3,2,0,0,202,8204,0,0,300,18000,0,0,95,2203,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,175 +17 2164 . G <*> 0 . DP=5;I16=3,2,0,0,179,6519,0,0,300,18000,0,0,95,2237,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,156 +17 2165 . C <*> 0 . DP=5;I16=3,2,0,0,173,6199,0,0,300,18000,0,0,94,2226,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,151 +17 2166 . T <*> 0 . DP=4;I16=2,2,0,0,152,5976,0,0,240,14400,0,0,94,2220,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,140 +17 2167 . A <*> 0 . DP=4;I16=2,1,0,0,117,4565,0,0,180,10800,0,0,72,1734,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,111 +17 2168 . C <*> 0 . DP=4;I16=2,2,0,0,135,4671,0,0,240,14400,0,0,93,2171,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,124 +17 2169 . T <*> 0 . DP=4;I16=2,2,0,0,154,6034,0,0,240,14400,0,0,92,2130,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,142 +17 2170 . C <*> 0 . DP=4;I16=2,2,0,0,147,5435,0,0,240,14400,0,0,91,2095,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,135 +17 2171 . C <*> 0 . DP=4;I16=2,2,0,0,151,5739,0,0,240,14400,0,0,89,2015,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,138 +17 2172 . T <*> 0 . DP=4;I16=2,2,0,0,160,6470,0,0,240,14400,0,0,87,1939,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,147 +17 2173 . G <*> 0 . DP=4;I16=2,2,0,0,145,5397,0,0,240,14400,0,0,85,1867,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,133 +17 2174 . G <*> 0 . DP=4;I16=2,2,0,0,140,5094,0,0,240,14400,0,0,83,1799,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,129 +17 2175 . G <*> 0 . DP=4;I16=2,2,0,0,137,4869,0,0,240,14400,0,0,81,1735,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,126 +17 2176 . G <*> 0 . DP=4;I16=2,2,0,0,134,4622,0,0,240,14400,0,0,79,1675,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,123 +17 2177 . T <*> 0 . DP=4;I16=2,2,0,0,116,3850,0,0,240,14400,0,0,77,1619,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,108 +17 2178 . T <*> 0 . DP=4;I16=2,2,0,0,127,4439,0,0,240,14400,0,0,75,1567,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,118 +17 2179 . T <*> 0 . DP=4;I16=2,2,0,0,147,5507,0,0,240,14400,0,0,73,1519,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,135 +17 2180 . T <*> 0 . DP=4;I16=2,2,0,0,145,5331,0,0,240,14400,0,0,71,1475,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,133 +17 2181 . C <*> 0 . DP=4;I16=2,2,0,0,164,6736,0,0,240,14400,0,0,69,1435,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,150 +17 2182 . C <*> 0 . DP=4;I16=2,2,0,0,159,6335,0,0,240,14400,0,0,67,1399,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,145 +17 2183 . A <*> 0 . DP=4;I16=2,2,0,0,157,6197,0,0,240,14400,0,0,65,1367,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,144 +17 2184 . T <*> 0 . DP=4;I16=2,2,0,0,148,5566,0,0,240,14400,0,0,63,1339,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,136 +17 2185 . C <*> 0 . DP=4;I16=2,2,0,0,149,5607,0,0,240,14400,0,0,61,1315,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,137 +17 2186 . A <*> 0 . DP=4;I16=2,2,0,0,159,6335,0,0,240,14400,0,0,59,1295,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,145 +17 2187 . A <*> 0 . DP=4;I16=2,2,0,0,148,5498,0,0,240,14400,0,0,57,1279,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,135 +17 2188 . A <*> 0 . DP=4;I16=2,2,0,0,135,4593,0,0,240,14400,0,0,55,1267,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,123 +17 2189 . C <*> 0 . DP=5;I16=2,3,0,0,162,5430,0,0,300,18000,0,0,53,1259,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,142 +17 2190 . C <*> 0 . DP=4;I16=1,3,0,0,120,3974,0,0,240,14400,0,0,53,1255,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,107 +17 2191 . C <*> 0 . DP=4;I16=1,3,0,0,134,4692,0,0,240,14400,0,0,53,1255,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,119 +17 2192 . T <*> 0 . DP=4;I16=1,3,0,0,137,4967,0,0,240,14400,0,0,53,1259,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,120 +17 2193 . C <*> 0 . DP=3;I16=0,3,0,0,101,3617,0,0,180,10800,0,0,54,1266,0,0;QS=1,0;MQ0F=0 PL 0,9,87 +17 2194 . A <*> 0 . DP=3;I16=0,3,0,0,117,4577,0,0,180,10800,0,0,55,1275,0,0;QS=1,0;MQ0F=0 PL 0,9,98 +17 2195 . A <*> 0 . DP=3;I16=0,3,0,0,119,4789,0,0,180,10800,0,0,56,1286,0,0;QS=1,0;MQ0F=0 PL 0,9,101 +17 2196 . G <*> 0 . DP=4;I16=0,4,0,0,155,6041,0,0,240,14400,0,0,57,1299,0,0;QS=1,0;MQ0F=0 PL 0,12,120 +17 2197 . A <*> 0 . DP=4;I16=0,4,0,0,162,6602,0,0,240,14400,0,0,59,1315,0,0;QS=1,0;MQ0F=0 PL 0,12,125 +17 2198 . G <*> 0 . DP=4;I16=0,4,0,0,134,4844,0,0,240,14400,0,0,61,1335,0,0;QS=1,0;MQ0F=0 PL 0,12,107 +17 2199 . C <*> 0 . DP=4;I16=0,4,0,0,150,5670,0,0,240,14400,0,0,63,1359,0,0;QS=1,0;MQ0F=0 PL 0,12,116 +17 2200 . T <*> 0 . DP=4;I16=0,4,0,0,147,5439,0,0,240,14400,0,0,65,1387,0,0;QS=1,0;MQ0F=0 PL 0,12,114 +17 2201 . G <*> 0 . DP=4;I16=0,4,0,0,154,5964,0,0,240,14400,0,0,67,1419,0,0;QS=1,0;MQ0F=0 PL 0,12,119 +17 2202 . G <*> 0 . DP=4;I16=0,4,0,0,148,5532,0,0,240,14400,0,0,69,1455,0,0;QS=1,0;MQ0F=0 PL 0,12,115 +17 2203 . G <*> 0 . DP=4;I16=0,4,0,0,149,5637,0,0,240,14400,0,0,71,1495,0,0;QS=1,0;MQ0F=0 PL 0,12,116 +17 2204 . C <*> 0 . DP=4;I16=0,4,0,0,124,4134,0,0,240,14400,0,0,73,1539,0,0;QS=1,0;MQ0F=0 PL 0,12,99 +17 2205 . C <*> 0 . DP=4;I16=0,4,0,0,139,4963,0,0,240,14400,0,0,75,1587,0,0;QS=1,0;MQ0F=0 PL 0,12,109 +17 2206 . T <*> 0 . DP=4;I16=0,4,0,0,149,5577,0,0,240,14400,0,0,77,1639,0,0;QS=1,0;MQ0F=0 PL 0,12,115 +17 2207 . G <*> 0 . DP=4;I16=0,4,0,0,141,5085,0,0,240,14400,0,0,79,1695,0,0;QS=1,0;MQ0F=0 PL 0,12,110 +17 2208 . G <*> 0 . DP=4;I16=0,4,0,0,158,6282,0,0,240,14400,0,0,81,1755,0,0;QS=1,0;MQ0F=0 PL 0,12,122 +17 2209 . G <*> 0 . DP=4;I16=0,4,0,0,151,5751,0,0,240,14400,0,0,83,1819,0,0;QS=1,0;MQ0F=0 PL 0,12,117 +17 2210 . G <*> 0 . DP=4;I16=0,4,0,0,145,5315,0,0,240,14400,0,0,85,1887,0,0;QS=1,0;MQ0F=0 PL 0,12,113 +17 2211 . T <*> 0 . DP=4;I16=0,4,0,0,162,6570,0,0,240,14400,0,0,86,1910,0,0;QS=1,0;MQ0F=0 PL 0,12,124 +17 2212 . C <*> 0 . DP=4;I16=0,4,0,0,143,5177,0,0,240,14400,0,0,87,1939,0,0;QS=1,0;MQ0F=0 PL 0,12,111 +17 2213 . A <*> 0 . DP=4;I16=0,4,0,0,144,5250,0,0,240,14400,0,0,88,1974,0,0;QS=1,0;MQ0F=0 PL 0,12,112 +17 2214 . A <*> 0 . DP=4;I16=0,4,0,0,150,5708,0,0,240,14400,0,0,89,2015,0,0;QS=1,0;MQ0F=0 PL 0,12,117 +17 2215 . C <*> 0 . DP=4;I16=0,4,0,0,160,6444,0,0,240,14400,0,0,89,2011,0,0;QS=1,0;MQ0F=0 PL 0,12,124 +17 2216 . T <*> 0 . DP=4;I16=0,4,0,0,158,6356,0,0,240,14400,0,0,89,2011,0,0;QS=1,0;MQ0F=0 PL 0,12,124 +17 2217 . T <*> 0 . DP=4;I16=0,4,0,0,150,5810,0,0,240,14400,0,0,89,2015,0,0;QS=1,0;MQ0F=0 PL 0,12,118 +17 2218 . C <*> 0 . DP=4;I16=0,4,0,0,154,5950,0,0,240,14400,0,0,89,2023,0,0;QS=1,0;MQ0F=0 PL 0,12,119 +17 2219 . C <*> 0 . DP=4;I16=0,4,0,0,159,6331,0,0,240,14400,0,0,89,2035,0,0;QS=1,0;MQ0F=0 PL 0,12,122 +17 2220 . G A,<*> 0 . DP=4;I16=0,0,0,4,0,0,170,7254,0,0,240,14400,0,0,89,2051;QS=0,1,0;VDB=0.775568;SGB=-0.556411;MQ0F=0 PL 131,12,0,131,12,131 +17 2221 . G <*> 0 . DP=4;I16=0,4,0,0,154,6054,0,0,240,14400,0,0,88,2022,0,0;QS=1,0;MQ0F=0 PL 0,12,120 +17 2222 . C <*> 0 . DP=4;I16=0,4,0,0,133,4857,0,0,240,14400,0,0,86,1948,0,0;QS=1,0;MQ0F=0 PL 0,12,107 +17 2223 . C <*> 0 . DP=4;I16=0,4,0,0,158,6262,0,0,240,14400,0,0,84,1878,0,0;QS=1,0;MQ0F=0 PL 0,12,122 +17 2224 . T <*> 0 . DP=4;I16=0,4,0,0,160,6424,0,0,240,14400,0,0,82,1812,0,0;QS=1,0;MQ0F=0 PL 0,12,123 +17 2225 . G <*> 0 . DP=4;I16=0,4,0,0,157,6195,0,0,240,14400,0,0,80,1750,0,0;QS=1,0;MQ0F=0 PL 0,12,121 +17 2226 . G <*> 0 . DP=4;I16=0,4,0,0,145,5349,0,0,240,14400,0,0,78,1692,0,0;QS=1,0;MQ0F=0 PL 0,12,113 +17 2227 . G <*> 0 . DP=4;I16=0,4,0,0,146,5406,0,0,240,14400,0,0,76,1638,0,0;QS=1,0;MQ0F=0 PL 0,12,114 +17 2228 . G <*> 0 . DP=4;I16=0,4,0,0,156,6128,0,0,240,14400,0,0,74,1588,0,0;QS=1,0;MQ0F=0 PL 0,12,121 +17 2229 . A <*> 0 . DP=4;I16=0,4,0,0,158,6274,0,0,240,14400,0,0,72,1542,0,0;QS=1,0;MQ0F=0 PL 0,12,122 +17 2230 . A <*> 0 . DP=4;I16=0,4,0,0,153,5909,0,0,240,14400,0,0,70,1500,0,0;QS=1,0;MQ0F=0 PL 0,12,119 +17 2231 . A <*> 0 . DP=4;I16=0,4,0,0,161,6493,0,0,240,14400,0,0,68,1462,0,0;QS=1,0;MQ0F=0 PL 0,12,124 +17 2232 . C <*> 0 . DP=4;I16=0,4,0,0,136,4778,0,0,240,14400,0,0,66,1428,0,0;QS=1,0;MQ0F=0 PL 0,12,107 +17 2233 . T <*> 0 . DP=4;I16=0,4,0,0,151,5737,0,0,240,14400,0,0,64,1398,0,0;QS=1,0;MQ0F=0 PL 0,12,117 +17 2234 . G <*> 0 . DP=4;I16=0,4,0,0,136,4756,0,0,240,14400,0,0,62,1372,0,0;QS=1,0;MQ0F=0 PL 0,12,107 +17 2235 . G <*> 0 . DP=4;I16=0,4,0,0,131,4533,0,0,240,14400,0,0,60,1350,0,0;QS=1,0;MQ0F=0 PL 0,12,104 +17 2236 . G <*> 0 . DP=3;I16=0,3,0,0,98,3410,0,0,180,10800,0,0,59,1331,0,0;QS=1,0;MQ0F=0 PL 0,9,84 +17 2237 . G <*> 0 . DP=3;I16=0,3,0,0,100,3686,0,0,180,10800,0,0,58,1314,0,0;QS=1,0;MQ0F=0 PL 0,9,86 +17 2238 . C <*> 0 . DP=3;I16=0,3,0,0,90,3012,0,0,180,10800,0,0,57,1299,0,0;QS=1,0;MQ0F=0 PL 0,9,78 +17 2239 . A <*> 0 . DP=3;I16=0,2,0,0,84,3528,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,77 +17 2240 . A <*> 0 . DP=3;I16=0,3,0,0,120,4842,0,0,180,10800,0,0,55,1275,0,0;QS=1,0;MQ0F=0 PL 0,9,101 +17 2241 . G <*> 0 . DP=3;I16=0,3,0,0,103,3701,0,0,180,10800,0,0,54,1266,0,0;QS=1,0;MQ0F=0 PL 0,9,88 +17 2242 . T <*> 0 . DP=3;I16=0,3,0,0,113,4275,0,0,180,10800,0,0,53,1259,0,0;QS=1,0;MQ0F=0 PL 0,9,95 +17 2243 . A <*> 0 . DP=3;I16=0,3,0,0,118,4658,0,0,180,10800,0,0,52,1254,0,0;QS=1,0;MQ0F=0 PL 0,9,99 +17 2244 . T <*> 0 . DP=3;I16=0,3,0,0,116,4574,0,0,180,10800,0,0,51,1251,0,0;QS=1,0;MQ0F=0 PL 0,9,98 +17 2245 . C <*> 0 . DP=3;I16=0,3,0,0,103,3765,0,0,180,10800,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,9,88 +17 2246 . A <*> 0 . DP=2;I16=0,2,0,0,79,3133,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,72 +17 2247 . C <*> 0 . DP=2;I16=0,2,0,0,78,3050,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,71 +17 2248 . C <*> 0 . DP=2;I16=0,2,0,0,82,3362,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,75 +17 2249 . A <*> 0 . DP=2;I16=0,2,0,0,88,3872,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,80 +17 2250 . G <*> 0 . DP=2;I16=0,2,0,0,86,3698,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,78 +17 2251 . A <*> 0 . DP=2;I16=0,2,0,0,88,3872,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,80 +17 2252 . G <*> 0 . DP=2;I16=0,2,0,0,80,3202,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,73 +17 2253 . A <*> 0 . DP=2;I16=0,2,0,0,80,3200,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,73 +17 2254 . T <*> 0 . DP=2;I16=0,2,0,0,80,3200,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,73 +17 2255 . G <*> 0 . DP=2;I16=0,2,0,0,77,2977,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,71 +17 2256 . A <*> 0 . DP=2;I16=0,2,0,0,85,3617,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,78 +17 2257 . G <*> 0 . DP=2;I16=0,2,0,0,81,3281,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,74 +17 2258 . C <*> 0 . DP=2;I16=0,2,0,0,76,2920,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,70 +17 2259 . T <*> 0 . DP=2;I16=0,2,0,0,87,3785,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,79 +17 2260 . T <*> 0 . DP=2;I16=0,2,0,0,78,3074,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,72 +17 2261 . T <*> 0 . DP=2;I16=0,2,0,0,80,3202,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,73 +17 2262 . A <*> 0 . DP=2;I16=0,2,0,0,81,3281,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,74 +17 2263 . T <*> 0 . DP=2;I16=0,2,0,0,81,3281,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,74 +17 2264 . A <*> 0 . DP=2;I16=0,2,0,0,82,3364,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,75 +17 2265 . A <*> 0 . DP=2;I16=0,2,0,0,82,3362,0,0,120,7200,0,0,49,1201,0,0;QS=1,0;MQ0F=0 PL 0,6,75 +17 2266 . A <*> 0 . DP=2;I16=0,2,0,0,82,3364,0,0,120,7200,0,0,48,1154,0,0;QS=1,0;MQ0F=0 PL 0,6,75 +17 2267 . A <*> 0 . DP=3;I16=1,2,0,0,109,4065,0,0,180,10800,0,0,47,1109,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,102 +17 2268 . A <*> 0 . DP=3;I16=1,2,0,0,106,3818,0,0,180,10800,0,0,47,1067,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,100 +17 2269 . T <*> 0 . DP=3;I16=1,2,0,0,117,4571,0,0,180,10800,0,0,47,1029,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,111 +17 2270 . A <*> 0 . DP=3;I16=1,2,0,0,119,4725,0,0,180,10800,0,0,47,995,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,112 +17 2271 . A <*> 0 . DP=3;I16=1,2,0,0,118,4644,0,0,180,10800,0,0,47,965,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,111 +17 2272 . T <*> 0 . DP=3;I16=1,2,0,0,118,4646,0,0,180,10800,0,0,46,890,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,111 +17 2273 . G <*> 0 . DP=3;I16=1,2,0,0,122,4966,0,0,180,10800,0,0,45,821,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,115 +17 2274 . G <*> 0 . DP=3;I16=1,2,0,0,116,4490,0,0,180,10800,0,0,44,758,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,110 +17 2275 . T <*> 0 . DP=3;I16=1,2,0,0,120,4802,0,0,180,10800,0,0,43,701,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,113 +17 2276 . G <*> 0 . DP=4;I16=1,2,0,0,117,4571,0,0,180,10800,0,0,42,650,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,110 +17 2277 . C <*> 0 . DP=4;I16=2,2,0,0,156,6092,0,0,240,14400,0,0,42,606,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,143 +17 2278 . T <*> 0 . DP=4;I16=2,2,0,0,162,6570,0,0,240,14400,0,0,42,570,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,148 +17 2279 . A <*> 0 . DP=4;I16=2,2,0,0,157,6177,0,0,240,14400,0,0,42,542,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,144 +17 2280 . G <*> 0 . DP=4;I16=2,2,0,0,158,6250,0,0,240,14400,0,0,42,522,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,144 +17 2281 . C <*> 0 . DP=4;I16=2,2,0,0,153,5879,0,0,240,14400,0,0,42,510,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,140 +17 2282 . T <*> 0 . DP=4;I16=2,2,0,0,164,6740,0,0,240,14400,0,0,42,506,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,150 +17 2283 . G <*> 0 . DP=4;I16=2,2,0,0,155,6015,0,0,240,14400,0,0,42,510,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,142 +17 2284 . G <*> 0 . DP=4;I16=2,2,0,0,154,5946,0,0,240,14400,0,0,42,522,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,141 +17 2285 . G <*> 0 . DP=4;I16=2,2,0,0,158,6254,0,0,240,14400,0,0,42,542,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,144 +17 2286 . C <*> 0 . DP=4;I16=2,2,0,0,141,5075,0,0,240,14400,0,0,42,570,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,130 +17 2287 . A <*> 0 . DP=4;I16=2,2,0,0,156,6094,0,0,240,14400,0,0,42,606,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,143 +17 2288 . T <*> 0 . DP=4;I16=2,2,0,0,156,6086,0,0,240,14400,0,0,42,650,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,142 +17 2289 . G <*> 0 . DP=4;I16=2,2,0,0,137,4801,0,0,240,14400,0,0,42,702,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,126 +17 2290 . G <*> 0 . DP=3;I16=2,1,0,0,121,4909,0,0,180,10800,0,0,43,761,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,114 +17 2291 . T <*> 0 . DP=3;I16=2,1,0,0,119,4721,0,0,180,10800,0,0,44,826,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,112 +17 2292 . G <*> 0 . DP=3;I16=2,1,0,0,115,4417,0,0,180,10800,0,0,45,897,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,109 +17 2293 . G <*> 0 . DP=3;I16=2,1,0,0,119,4733,0,0,180,10800,0,0,45,923,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,112 +17 2294 . C <*> 0 . DP=3;I16=2,1,0,0,121,4899,0,0,180,10800,0,0,45,953,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,114 +17 2295 . T <*> 0 . DP=3;I16=2,1,0,0,122,5010,0,0,180,10800,0,0,45,987,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,115 +17 2296 . T <*> 0 . DP=3;I16=2,1,0,0,113,4345,0,0,180,10800,0,0,45,1025,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,106 +17 2297 . G <*> 0 . DP=2;I16=2,0,0,0,81,3281,0,0,120,7200,0,0,46,1066,0,0;QS=1,0;MQ0F=0 PL 0,6,74 +17 2298 . C <*> 0 . DP=3;I16=2,1,0,0,113,4349,0,0,180,10800,0,0,47,1109,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,106 +17 2299 . A <*> 0 . DP=3;I16=2,1,0,0,117,4577,0,0,180,10800,0,0,49,1155,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,110 +17 2300 . C <*> 0 . DP=3;I16=2,1,0,0,116,4506,0,0,180,10800,0,0,51,1205,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,109 +17 2301 . C <*> 0 . DP=4;I16=2,1,0,0,123,5067,0,0,180,10800,0,0,53,1259,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,116 +17 2302 . T <*> 0 . DP=4;I16=2,2,0,0,164,6750,0,0,240,14400,0,0,57,1275,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,150 +17 2303 . G <*> 0 . DP=4;I16=2,2,0,0,152,5838,0,0,240,14400,0,0,59,1291,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,139 +17 2304 . T <*> 0 . DP=4;I16=2,2,0,0,153,5891,0,0,240,14400,0,0,61,1311,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,140 +17 2305 . A <*> 0 . DP=4;I16=2,2,0,0,140,5134,0,0,240,14400,0,0,63,1335,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,129 +17 2306 . A <*> 0 . DP=4;I16=2,2,0,0,140,5562,0,0,240,14400,0,0,65,1363,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,130 +17 2307 . T <*> 0 . DP=4;I16=2,2,0,0,154,5972,0,0,240,14400,0,0,67,1395,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,141 +17 2308 . C <*> 0 . DP=4;I16=2,2,0,0,159,6375,0,0,240,14400,0,0,69,1431,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,146 +17 2309 . C <*> 0 . DP=4;I16=2,2,0,0,151,5835,0,0,240,14400,0,0,71,1471,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,138 +17 2310 . C <*> 0 . DP=4;I16=2,2,0,0,151,5883,0,0,240,14400,0,0,73,1515,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,139 +17 2311 . A <*> 0 . DP=4;I16=2,2,0,0,149,5751,0,0,240,14400,0,0,75,1563,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,137 +17 2312 . G <*> 0 . DP=4;I16=2,1,0,0,129,5553,0,0,180,10800,0,0,64,1446,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,122 +17 2313 . C <*> 0 . DP=4;I16=2,2,0,0,141,5299,0,0,240,14400,0,0,79,1671,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,130 +17 2314 . A <*> 0 . DP=4;I16=2,1,0,0,122,4964,0,0,180,10800,0,0,66,1506,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,115 +17 2315 . C <*> 0 . DP=5;I16=2,2,0,0,147,5507,0,0,240,14400,0,0,83,1795,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,135 +17 2316 . T <*> 0 . DP=5;I16=2,3,0,0,196,7766,0,0,300,18000,0,0,94,1944,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,170 +17 2317 . T <*> 0 . DP=5;I16=2,3,0,0,196,7722,0,0,300,18000,0,0,97,2035,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,170 +17 2318 . T <*> 0 . DP=5;I16=2,3,0,0,189,7259,0,0,300,18000,0,0,100,2132,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,165 +17 2319 . G <*> 0 . DP=5;I16=2,3,0,0,192,7438,0,0,300,18000,0,0,103,2235,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,167 +17 2320 . G <*> 0 . DP=5;I16=2,3,0,0,180,6640,0,0,300,18000,0,0,106,2344,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,157 +17 2321 . G <*> 0 . DP=5;I16=2,3,0,0,193,7589,0,0,300,18000,0,0,109,2459,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,169 +17 2322 . A <*> 0 . DP=5;I16=2,3,0,0,205,8431,0,0,300,18000,0,0,112,2580,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,178 +17 2323 . G <*> 0 . DP=5;I16=2,3,0,0,176,6236,0,0,300,18000,0,0,115,2707,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,153 +17 2324 . G <*> 0 . DP=5;I16=2,3,0,0,184,6886,0,0,300,18000,0,0,117,2789,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,161 +17 2325 . C <*> 0 . DP=5;I16=2,2,0,0,141,5179,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,130 +17 2326 . C <*> 0 . DP=5;I16=2,2,0,0,145,5391,0,0,240,14400,0,0,94,2236,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,133 +17 2327 . G <*> 0 . DP=5;I16=2,3,0,0,182,6706,0,0,300,18000,0,0,120,2900,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,158 +17 2328 . A <*> 0 . DP=5;I16=2,3,0,0,196,7864,0,0,300,18000,0,0,121,2941,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,172 +17 2329 . G <*> 0 . DP=5;I16=2,3,0,0,182,6898,0,0,300,18000,0,0,122,2984,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,160 +17 2330 . C <*> 0 . DP=6;I16=2,4,0,0,218,8192,0,0,360,21600,0,0,123,3029,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,181 +17 2331 . T <*> 0 . DP=6;I16=2,4,0,0,245,10069,0,0,360,21600,0,0,125,3077,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,200 +17 2332 . A <*> 0 . DP=6;I16=2,4,0,0,249,10383,0,0,360,21600,0,0,127,3129,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,204 +17 2333 . G <*> 0 . DP=7;I16=2,4,0,0,231,8953,0,0,360,21600,0,0,103,2509,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,189 +17 2334 . G <*> 0 . DP=7;I16=2,5,0,0,262,9874,0,0,420,25200,0,0,130,3142,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,202 +17 2335 . A <*> 0 . DP=7;I16=2,5,0,0,276,11088,0,0,420,25200,0,0,132,3154,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,214 +17 2336 . G <*> 0 . DP=7;I16=2,5,0,0,267,10225,0,0,420,25200,0,0,134,3170,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,204 +17 2337 . G <*> 0 . DP=7;I16=2,5,0,0,267,10239,0,0,420,25200,0,0,136,3190,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,204 +17 2338 . A <*> 0 . DP=7;I16=2,5,0,0,249,9131,0,0,420,25200,0,0,138,3214,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,194 +17 2339 . T <*> 0 . DP=7;I16=2,5,0,0,255,9565,0,0,420,25200,0,0,140,3242,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,200 +17 2340 . C <*> 0 . DP=7;I16=2,5,0,0,223,7325,0,0,420,25200,0,0,142,3274,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,173 +17 2341 . G <*> 0 . DP=7;I16=2,5,0,0,240,8346,0,0,420,25200,0,0,144,3310,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,186 +17 2342 . T <*> 0 . DP=7;I16=2,5,0,0,277,11065,0,0,420,25200,0,0,146,3350,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,214 +17 2343 . T <*> 0 . DP=7;I16=2,5,0,0,276,11018,0,0,420,25200,0,0,147,3345,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,213 +17 2344 . T <*> 0 . DP=7;I16=2,5,0,0,261,9857,0,0,420,25200,0,0,148,3346,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,202 +17 2345 . G <*> 0 . DP=7;I16=2,5,0,0,267,10239,0,0,420,25200,0,0,149,3353,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,206 +17 2346 . A <*> 0 . DP=7;I16=2,5,0,0,285,11661,0,0,420,25200,0,0,150,3366,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,220 +17 2347 . G <*> 0 . DP=7;I16=2,5,0,0,244,8718,0,0,420,25200,0,0,151,3385,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,190 +17 2348 . T <*> 0 . DP=7;I16=2,4,0,0,220,8336,0,0,360,21600,0,0,137,3185,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,183 +17 2349 . C <*> 0 . DP=7;I16=2,5,0,0,258,9658,0,0,420,25200,0,0,153,3441,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,200 +17 2350 . C <*> 0 . DP=7;I16=2,5,0,0,255,9511,0,0,420,25200,0,0,154,3478,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,198 +17 2351 . A <*> 0 . DP=7;I16=2,5,0,0,289,11991,0,0,420,25200,0,0,155,3521,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,222 +17 2352 . G <*> 0 . DP=7;I16=2,5,0,0,271,10521,0,0,420,25200,0,0,155,3521,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,207 +17 2353 . C <*> 0 . DP=7;I16=2,5,0,0,267,10253,0,0,420,25200,0,0,155,3529,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,205 +17 2354 . A <*> 0 . DP=7;I16=2,5,0,0,277,11071,0,0,420,25200,0,0,155,3545,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,214 +17 2355 . G <*> 0 . DP=7;I16=2,5,0,0,254,9266,0,0,420,25200,0,0,155,3569,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,195 +17 2356 . T <*> 0 . DP=7;I16=2,5,0,0,285,11661,0,0,420,25200,0,0,154,3550,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,219 +17 2357 . T <*> 0 . DP=7;I16=2,5,0,0,285,11651,0,0,420,25200,0,0,153,3537,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,220 +17 2358 . T <*> 0 . DP=7;I16=2,5,0,0,284,11544,0,0,420,25200,0,0,152,3530,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,218 +17 2359 . G <*> 0 . DP=7;I16=2,5,0,0,275,10815,0,0,420,25200,0,0,150,3478,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,209 +17 2360 . A <*> 0 . DP=7;I16=2,5,0,0,289,11959,0,0,420,25200,0,0,148,3430,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,222 +17 2361 . G <*> 0 . DP=7;I16=2,4,0,0,205,7077,0,0,360,21600,0,0,121,2761,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,168 +17 2362 . A <*> 0 . DP=7;I16=2,4,0,0,189,6417,0,0,360,21600,0,0,119,2721,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,159 +17 2363 . C <*> 0 . DP=7;I16=2,5,0,0,236,8478,0,0,420,25200,0,0,142,3310,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,187 +17 2364 . C <*> 0 . DP=7;I16=2,5,0,0,263,9923,0,0,420,25200,0,0,140,3278,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,201 +17 2365 . A <*> 0 . DP=7;I16=2,5,0,0,286,11700,0,0,420,25200,0,0,138,3250,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,221 +17 2366 . G <*> 0 . DP=7;I16=2,5,0,0,267,10253,0,0,420,25200,0,0,136,3226,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,206 +17 2367 . C <*> 0 . DP=7;I16=2,5,0,0,254,9344,0,0,420,25200,0,0,134,3206,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,197 +17 2368 . C <*> 0 . DP=6;I16=1,5,0,0,239,9547,0,0,360,21600,0,0,133,3189,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,180 +17 2369 . T <*> 0 . DP=6;I16=1,5,0,0,237,9409,0,0,360,21600,0,0,132,3174,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,179 +17 2370 . G <*> 0 . DP=6;I16=1,5,0,0,236,9334,0,0,360,21600,0,0,131,3161,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,179 +17 2371 . G <*> 0 . DP=6;I16=1,5,0,0,233,9111,0,0,360,21600,0,0,130,3150,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,177 +17 2372 . C <*> 0 . DP=6;I16=1,5,0,0,216,7802,0,0,360,21600,0,0,129,3141,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,163 +17 2373 . C <*> 0 . DP=6;I16=1,5,0,0,220,8088,0,0,360,21600,0,0,128,3134,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,166 +17 2374 . A <*> 0 . DP=6;I16=1,5,0,0,232,9038,0,0,360,21600,0,0,126,3080,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,177 +17 2375 . A <*> 0 . DP=6;I16=1,5,0,0,222,8246,0,0,360,21600,0,0,123,2981,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,171 +17 2376 . T <*> 0 . DP=6;I16=1,5,0,0,210,7540,0,0,360,21600,0,0,120,2888,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,162 +17 2377 . A <*> 0 . DP=5;I16=0,5,0,0,189,7193,0,0,300,18000,0,0,118,2800,0,0;QS=1,0;MQ0F=0 PL 0,15,135 +17 2378 . C <*> 0 . DP=5;I16=0,5,0,0,155,4809,0,0,300,18000,0,0,116,2716,0,0;QS=1,0;MQ0F=0 PL 0,15,108 +17 2379 . G <*> 0 . DP=5;I16=0,5,0,0,198,7862,0,0,300,18000,0,0,114,2636,0,0;QS=1,0;MQ0F=0 PL 0,15,140 +17 2380 . G <*> 0 . DP=5;I16=0,5,0,0,187,7071,0,0,300,18000,0,0,112,2560,0,0;QS=1,0;MQ0F=0 PL 0,15,134 +17 2381 . C <*> 0 . DP=5;I16=0,5,0,0,185,6943,0,0,300,18000,0,0,110,2488,0,0;QS=1,0;MQ0F=0 PL 0,15,133 +17 2382 . A <*> 0 . DP=5;I16=0,5,0,0,180,6734,0,0,300,18000,0,0,108,2420,0,0;QS=1,0;MQ0F=0 PL 0,15,131 +17 2383 . A <*> 0 . DP=5;I16=0,5,0,0,197,7813,0,0,300,18000,0,0,105,2307,0,0;QS=1,0;MQ0F=0 PL 0,15,140 +17 2384 . A <*> 0 . DP=5;I16=0,5,0,0,185,6925,0,0,300,18000,0,0,102,2200,0,0;QS=1,0;MQ0F=0 PL 0,15,132 +17 2385 . A <*> 0 . DP=5;I16=0,5,0,0,190,7234,0,0,300,18000,0,0,99,2099,0,0;QS=1,0;MQ0F=0 PL 0,15,134 +17 2386 . C <*> 0 . DP=5;I16=0,5,0,0,181,6715,0,0,300,18000,0,0,96,2004,0,0;QS=1,0;MQ0F=0 PL 0,15,130 +17 2387 . C <*> 0 . DP=5;I16=0,5,0,0,182,6628,0,0,300,18000,0,0,93,1915,0,0;QS=1,0;MQ0F=0 PL 0,15,128 +17 2388 . C <*> 0 . DP=5;I16=0,5,0,0,189,7169,0,0,300,18000,0,0,90,1832,0,0;QS=1,0;MQ0F=0 PL 0,15,134 +17 2389 . A <*> 0 . DP=5;I16=0,5,0,0,195,7765,0,0,300,18000,0,0,87,1755,0,0;QS=1,0;MQ0F=0 PL 0,15,140 +17 2390 . G <*> 0 . DP=5;I16=0,5,0,0,178,6372,0,0,300,18000,0,0,84,1684,0,0;QS=1,0;MQ0F=0 PL 0,15,126 +17 2391 . T <*> 0 . DP=5;I16=0,5,0,0,196,7750,0,0,300,18000,0,0,81,1619,0,0;QS=1,0;MQ0F=0 PL 0,15,140 +17 2392 . C <*> 0 . DP=5;I16=0,5,0,0,181,6723,0,0,300,18000,0,0,78,1560,0,0;QS=1,0;MQ0F=0 PL 0,15,131 +17 2393 . T <*> 0 . DP=5;I16=0,5,0,0,187,7067,0,0,300,18000,0,0,75,1507,0,0;QS=1,0;MQ0F=0 PL 0,15,134 +17 2394 . C <*> 0 . DP=5;I16=0,5,0,0,186,6976,0,0,300,18000,0,0,72,1460,0,0;QS=1,0;MQ0F=0 PL 0,15,133 +17 2395 . T <*> 0 . DP=5;I16=0,5,0,0,179,6497,0,0,300,18000,0,0,69,1419,0,0;QS=1,0;MQ0F=0 PL 0,15,128 +17 2396 . A <*> 0 . DP=5;I16=0,5,0,0,184,6802,0,0,300,18000,0,0,66,1384,0,0;QS=1,0;MQ0F=0 PL 0,15,130 +17 2397 . C <*> 0 . DP=5;I16=0,5,0,0,182,6652,0,0,300,18000,0,0,63,1355,0,0;QS=1,0;MQ0F=0 PL 0,15,129 +17 2398 . A <*> 0 . DP=5;I16=0,5,0,0,177,6407,0,0,300,18000,0,0,60,1332,0,0;QS=1,0;MQ0F=0 PL 0,15,128 +17 2399 . A <*> 0 . DP=4;I16=0,4,0,0,147,5559,0,0,240,14400,0,0,58,1314,0,0;QS=1,0;MQ0F=0 PL 0,12,115 +17 2400 . A <*> 0 . DP=3;I16=0,3,0,0,119,4723,0,0,180,10800,0,0,57,1299,0,0;QS=1,0;MQ0F=0 PL 0,9,99 +17 2401 . A <*> 0 . DP=3;I16=0,3,0,0,118,4642,0,0,180,10800,0,0,56,1286,0,0;QS=1,0;MQ0F=0 PL 0,9,98 +17 2402 . A <*> 0 . DP=3;I16=0,3,0,0,119,4721,0,0,180,10800,0,0,55,1275,0,0;QS=1,0;MQ0F=0 PL 0,9,99 +17 2403 . A <*> 0 . DP=3;I16=0,3,0,0,116,4490,0,0,180,10800,0,0,54,1266,0,0;QS=1,0;MQ0F=0 PL 0,9,97 +17 2404 . T <*> 0 . DP=3;I16=0,3,0,0,104,3608,0,0,180,10800,0,0,53,1259,0,0;QS=1,0;MQ0F=0 PL 0,9,87 +17 2405 . A <*> 0 . DP=3;I16=0,3,0,0,104,3658,0,0,180,10800,0,0,52,1254,0,0;QS=1,0;MQ0F=0 PL 0,9,88 +17 2406 . C <*> 0 . DP=3;I16=0,3,0,0,108,3896,0,0,180,10800,0,0,50,1202,0,0;QS=1,0;MQ0F=0 PL 0,9,90 +17 2407 . A <*> 0 . DP=3;I16=0,3,0,0,105,3731,0,0,180,10800,0,0,48,1154,0,0;QS=1,0;MQ0F=0 PL 0,9,89 +17 2408 . A <*> 0 . DP=2;I16=0,2,0,0,80,3202,0,0,120,7200,0,0,47,1109,0,0;QS=1,0;MQ0F=0 PL 0,6,73 +17 2409 . A <*> 0 . DP=2;I16=0,2,0,0,81,3281,0,0,120,7200,0,0,45,1017,0,0;QS=1,0;MQ0F=0 PL 0,6,74 +17 2410 . A <*> 0 . DP=2;I16=0,2,0,0,80,3200,0,0,120,7200,0,0,43,929,0,0;QS=1,0;MQ0F=0 PL 0,6,73 +17 2411 . A <*> 0 . DP=2;I16=0,2,0,0,76,2906,0,0,120,7200,0,0,41,845,0,0;QS=1,0;MQ0F=0 PL 0,6,70 +17 2412 . A <*> 0 . DP=2;I16=0,2,0,0,76,2906,0,0,120,7200,0,0,39,765,0,0;QS=1,0;MQ0F=0 PL 0,6,70 +17 2413 . C <*> 0 . DP=2;I16=0,2,0,0,79,3121,0,0,120,7200,0,0,37,689,0,0;QS=1,0;MQ0F=0 PL 0,6,72 +17 2414 . A <*> 0 . DP=2;I16=0,2,0,0,80,3202,0,0,120,7200,0,0,35,617,0,0;QS=1,0;MQ0F=0 PL 0,6,73 +17 2415 . A <*> 0 . DP=2;I16=0,2,0,0,70,2452,0,0,120,7200,0,0,33,549,0,0;QS=1,0;MQ0F=0 PL 0,6,64 +17 2416 . C <*> 0 . DP=2;I16=0,2,0,0,74,2756,0,0,120,7200,0,0,31,485,0,0;QS=1,0;MQ0F=0 PL 0,6,68 +17 2417 . T <*> 0 . DP=3;I16=1,2,0,0,97,3249,0,0,149,8041,0,0,29,425,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,92 +17 2418 . A <*> 0 . DP=3;I16=1,2,0,0,119,4741,0,0,149,8041,0,0,28,370,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,105 +17 2419 . G <*> 0 . DP=4;I16=2,2,0,0,142,5114,0,0,209,11641,0,0,27,321,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,12,126 +17 2420 . C <*> 0 . DP=4;I16=2,2,0,0,146,5362,0,0,209,11641,0,0,27,279,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,12,127 +17 2421 . C <*> 0 . DP=4;I16=2,2,0,0,139,4885,0,0,209,11641,0,0,27,245,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,12,126 +17 2422 . A <*> 0 . DP=4;I16=2,2,0,0,159,6335,0,0,209,11641,0,0,27,219,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,12,137 +17 2423 . G <*> 0 . DP=4;I16=2,2,0,0,148,5486,0,0,209,11641,0,0,27,201,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,12,126 +17 2424 . G <*> 0 . DP=4;I16=2,2,0,0,137,4787,0,0,209,11641,0,0,27,191,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,12,126 +17 2425 . C <*> 0 . DP=4;I16=2,2,0,0,133,4541,0,0,209,11641,0,0,27,189,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,12,114 +17 2426 . G <*> 0 . DP=4;I16=2,2,0,0,124,3894,0,0,209,11641,0,0,27,195,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,12,113 +17 2427 . T <*> 0 . DP=4;I16=2,1,0,0,105,3731,0,0,149,8041,0,0,24,200,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,99 +17 2428 . G <*> 0 . DP=4;I16=2,2,0,0,145,5265,0,0,209,11641,0,0,27,231,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,12,128 +17 2429 . G <*> 0 . DP=4;I16=2,2,0,0,135,4571,0,0,209,11641,0,0,27,261,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,12,117 +17 2430 . T <*> 0 . DP=4;I16=2,2,0,0,141,5005,0,0,209,11641,0,0,27,299,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,12,125 +17 2431 . G <*> 0 . DP=3;I16=2,1,0,0,114,4338,0,0,149,8041,0,0,28,344,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,98 +17 2432 . G <*> 0 . DP=3;I16=2,1,0,0,113,4261,0,0,149,8041,0,0,29,395,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,97 +17 2433 . T <*> 0 . DP=3;I16=2,1,0,0,99,3365,0,0,149,8041,0,0,30,452,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,94 +17 2434 . G <*> 0 . DP=2;I16=2,0,0,0,67,2285,0,0,89,4441,0,0,32,514,0,0;QS=1,0;MQ0F=0 PL 0,6,62 +17 2435 . C <*> 0 . DP=2;I16=2,0,0,0,66,2196,0,0,89,4441,0,0,34,580,0,0;QS=1,0;MQ0F=0 PL 0,6,60 +17 2436 . A <*> 0 . DP=2;I16=2,0,0,0,77,2969,0,0,89,4441,0,0,36,650,0,0;QS=1,0;MQ0F=0 PL 0,6,61 +17 2437 . C <*> 0 . DP=2;I16=2,0,0,0,74,2746,0,0,89,4441,0,0,38,724,0,0;QS=1,0;MQ0F=0 PL 0,6,63 +17 2438 . A <*> 0 . DP=2;I16=2,0,0,0,77,2977,0,0,89,4441,0,0,40,802,0,0;QS=1,0;MQ0F=0 PL 0,6,65 +17 2439 . C <*> 0 . DP=2;I16=2,0,0,0,62,1954,0,0,89,4441,0,0,42,884,0,0;QS=1,0;MQ0F=0 PL 0,6,57 +17 2440 . C <*> 0 . DP=2;I16=2,0,0,0,75,2853,0,0,89,4441,0,0,44,970,0,0;QS=1,0;MQ0F=0 PL 0,6,66 +17 2441 . T <*> 0 . DP=2;I16=2,0,0,0,84,3530,0,0,89,4441,0,0,46,1060,0,0;QS=1,0;MQ0F=0 PL 0,6,67 +17 2442 . G <*> 0 . DP=2;I16=2,0,0,0,79,3133,0,0,89,4441,0,0,48,1154,0,0;QS=1,0;MQ0F=0 PL 0,6,66 +17 2443 . T <*> 0 . DP=2;I16=2,0,0,0,76,2896,0,0,89,4441,0,0,49,1201,0,0;QS=1,0;MQ0F=0 PL 0,6,64 +17 2444 . A <*> 0 . DP=2;I16=2,0,0,0,80,3200,0,0,89,4441,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,64 +17 2445 . G <*> 0 . DP=2;I16=2,0,0,0,80,3202,0,0,89,4441,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,65 +17 2446 . T <*> 0 . DP=2;I16=2,0,0,0,79,3125,0,0,89,4441,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,65 +17 2447 . C <*> 0 . DP=2;I16=2,0,0,0,77,2969,0,0,89,4441,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,64 +17 2448 . C <*> 0 . DP=2;I16=2,0,0,0,81,3285,0,0,89,4441,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,66 +17 2449 . C <*> 0 . DP=2;I16=2,0,0,0,80,3208,0,0,89,4441,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,62 +17 2450 . A <*> 0 . DP=2;I16=2,0,0,0,82,3362,0,0,89,4441,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,65 +17 2451 . G <*> 0 . DP=2;I16=2,0,0,0,82,3370,0,0,89,4441,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,67 +17 2452 . C <*> 0 . DP=2;I16=2,0,0,0,78,3060,0,0,89,4441,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,66 +17 2453 . T <*> 0 . DP=2;I16=2,0,0,0,88,3872,0,0,89,4441,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,68 +17 2454 . A <*> 0 . DP=2;I16=2,0,0,0,75,2825,0,0,89,4441,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,64 +17 2455 . C <*> 0 . DP=2;I16=2,0,0,0,75,2837,0,0,89,4441,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,65 +17 2456 . T <*> 0 . DP=2;I16=2,0,0,0,79,3145,0,0,89,4441,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,60 +17 2457 . C <*> 0 . DP=2;I16=2,0,0,0,79,3125,0,0,89,4441,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,65 +17 2458 . A <*> 0 . DP=2;I16=2,0,0,0,81,3281,0,0,89,4441,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,65 +17 2459 . G <*> 0 . DP=2;I16=2,0,0,0,77,2969,0,0,89,4441,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,64 +17 2460 . G <*> 0 . DP=2;I16=2,0,0,0,81,3281,0,0,89,4441,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,65 +17 2461 . A <*> 0 . DP=2;I16=2,0,0,0,86,3698,0,0,89,4441,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,67 +17 2462 . G <*> 0 . DP=2;I16=2,0,0,0,84,3528,0,0,89,4441,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,66 +17 2463 . G <*> 0 . DP=2;I16=2,0,0,0,85,3617,0,0,89,4441,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,68 +17 2464 . C <*> 0 . DP=2;I16=2,0,0,0,84,3530,0,0,89,4441,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,67 +17 2465 . T <*> 0 . DP=2;I16=2,0,0,0,88,3874,0,0,89,4441,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,69 +17 2466 . G <*> 0 . DP=2;I16=2,0,0,0,77,2965,0,0,89,4441,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,63 +17 2467 . A <*> 0 . DP=2;I16=2,0,0,0,83,3449,0,0,89,4441,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,67 +17 2468 . G <*> 0 . DP=2;I16=2,0,0,0,80,3200,0,0,89,4441,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,64 +17 2469 . G <*> 0 . DP=2;I16=2,0,0,0,69,2381,0,0,89,4441,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,58 +17 2470 . G <*> 0 . DP=2;I16=2,0,0,0,68,2312,0,0,89,4441,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,58 +17 2471 . G <*> 0 . DP=2;I16=2,0,0,0,81,3281,0,0,89,4441,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,64 +17 2472 . G <*> 0 . DP=2;I16=2,0,0,0,59,2005,0,0,89,4441,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,56 +17 2473 . A <*> 0 . DP=2;I16=2,0,0,0,77,2965,0,0,89,4441,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,63 +17 2474 . A <*> 0 . DP=3;I16=3,0,0,0,105,3717,0,0,149,8041,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,9,80 +17 2475 . G <*> 0 . DP=3;I16=3,0,0,0,109,3965,0,0,149,8041,0,0,51,1251,0,0;QS=1,0;MQ0F=0 PL 0,9,84 +17 2476 . G <*> 0 . DP=3;I16=3,0,0,0,105,3677,0,0,149,8041,0,0,52,1254,0,0;QS=1,0;MQ0F=0 PL 0,9,82 +17 2477 . A <*> 0 . DP=3;I16=3,0,0,0,116,4488,0,0,149,8041,0,0,53,1259,0,0;QS=1,0;MQ0F=0 PL 0,9,91 +17 2478 . C <*> 0 . DP=3;I16=3,0,0,0,108,3902,0,0,149,8041,0,0,54,1266,0,0;QS=1,0;MQ0F=0 PL 0,9,87 +17 2479 . T <*> 0 . DP=3;I16=3,0,0,0,127,5377,0,0,149,8041,0,0,55,1275,0,0;QS=1,0;MQ0F=0 PL 0,9,97 +17 2480 . G <*> 0 . DP=3;I16=3,0,0,0,109,3969,0,0,149,8041,0,0,56,1286,0,0;QS=1,0;MQ0F=0 PL 0,9,88 +17 2481 . C <*> 0 . DP=3;I16=3,0,0,0,112,4182,0,0,149,8041,0,0,57,1299,0,0;QS=1,0;MQ0F=0 PL 0,9,88 +17 2482 . T <*> 0 . DP=3;I16=3,0,0,0,126,5292,0,0,149,8041,0,0,58,1314,0,0;QS=1,0;MQ0F=0 PL 0,9,96 +17 2483 . T <*> 0 . DP=3;I16=3,0,0,0,111,4113,0,0,149,8041,0,0,59,1331,0,0;QS=1,0;MQ0F=0 PL 0,9,89 +17 2484 . G <*> 0 . DP=3;I16=3,0,0,0,110,4046,0,0,149,8041,0,0,60,1350,0,0;QS=1,0;MQ0F=0 PL 0,9,84 +17 2485 . A <*> 0 . DP=3;I16=3,0,0,0,121,4885,0,0,149,8041,0,0,61,1371,0,0;QS=1,0;MQ0F=0 PL 0,9,93 +17 2486 . G <*> 0 . DP=3;I16=3,0,0,0,116,4486,0,0,149,8041,0,0,62,1394,0,0;QS=1,0;MQ0F=0 PL 0,9,90 +17 2487 . C <*> 0 . DP=3;I16=3,0,0,0,116,4488,0,0,149,8041,0,0,63,1419,0,0;QS=1,0;MQ0F=0 PL 0,9,91 +17 2488 . C <*> 0 . DP=3;I16=3,0,0,0,119,4729,0,0,149,8041,0,0,64,1446,0,0;QS=1,0;MQ0F=0 PL 0,9,93 +17 2489 . C <*> 0 . DP=3;I16=3,0,0,0,116,4504,0,0,149,8041,0,0,65,1475,0,0;QS=1,0;MQ0F=0 PL 0,9,93 +17 2490 . A <*> 0 . DP=4;I16=3,1,0,0,151,5721,0,0,209,11641,0,0,66,1506,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,128 +17 2491 . G <*> 0 . DP=4;I16=3,1,0,0,145,5265,0,0,209,11641,0,0,68,1540,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,121 +17 2492 . G <*> 0 . DP=4;I16=3,1,0,0,140,5006,0,0,209,11641,0,0,70,1578,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,124 +17 2493 . A <*> 0 . DP=4;I16=3,1,0,0,151,5729,0,0,209,11641,0,0,71,1571,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,127 +17 2494 . G <*> 0 . DP=4;I16=3,1,0,0,140,4942,0,0,209,11641,0,0,72,1570,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,118 +17 2495 . T <*> 0 . DP=4;I16=3,1,0,0,126,4266,0,0,209,11641,0,0,72,1526,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,113 +17 2496 . T <*> 0 . DP=4;I16=3,1,0,0,137,4977,0,0,209,11641,0,0,72,1490,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,123 +17 2497 . T <*> 0 . DP=4;I16=3,1,0,0,157,6169,0,0,209,11641,0,0,72,1462,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,131 +17 2498 . G <*> 0 . DP=4;I16=3,1,0,0,148,5512,0,0,209,11641,0,0,72,1442,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,127 +17 2499 . A <*> 0 . DP=4;I16=3,1,0,0,162,6620,0,0,209,11641,0,0,72,1430,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,133 +17 2500 . G <*> 0 . DP=4;I16=3,1,0,0,152,5802,0,0,209,11641,0,0,71,1375,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,129 +17 2501 . G <*> 0 . DP=4;I16=3,1,0,0,143,5181,0,0,209,11641,0,0,70,1326,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,118 +17 2502 . C <*> 0 . DP=4;I16=3,1,0,0,142,5094,0,0,209,11641,0,0,69,1283,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,125 +17 2503 . T <*> 0 . DP=4;I16=3,1,0,0,168,7060,0,0,209,11641,0,0,68,1246,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,139 +17 2504 . G <*> 0 . DP=4;I16=3,1,0,0,152,5812,0,0,209,11641,0,0,67,1215,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,129 +17 2505 . C <*> 0 . DP=4;I16=3,1,0,0,157,6177,0,0,209,11641,0,0,66,1190,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,132 +17 2506 . T <*> 0 . DP=5;I16=3,2,0,0,193,7635,0,0,269,15241,0,0,65,1171,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL 0,15,169 +17 2507 . G <*> 0 . DP=5;I16=3,2,0,0,174,6350,0,0,269,15241,0,0,65,1159,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL 0,15,153 +17 2508 . T <*> 0 . DP=5;I16=3,2,0,0,191,7331,0,0,269,15241,0,0,65,1155,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL 0,15,162 +17 2509 . G <*> 0 . DP=5;I16=3,2,0,0,192,7402,0,0,269,15241,0,0,65,1159,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL 0,15,163 +17 2510 . A <*> 0 . DP=5;I16=3,2,0,0,190,7330,0,0,269,15241,0,0,65,1171,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL 0,15,161 +17 2511 . G <*> 0 . DP=5;I16=3,2,0,0,186,6948,0,0,269,15241,0,0,65,1191,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL 0,15,159 +17 2512 . C <*> 0 . DP=5;I16=3,2,0,0,192,7376,0,0,269,15241,0,0,65,1219,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL 0,15,160 +17 2513 . T <*> 0 . DP=5;I16=3,2,0,0,185,6911,0,0,269,15241,0,0,65,1255,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL 0,15,156 +17 2514 . G <*> 0 . DP=5;I16=3,2,0,0,181,6599,0,0,269,15241,0,0,65,1299,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL 0,15,155 +17 2515 . T <*> 0 . DP=5;I16=3,2,0,0,170,5938,0,0,269,15241,0,0,65,1351,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL 0,15,141 +17 2516 . G <*> 0 . DP=5;I16=3,2,0,0,176,6216,0,0,269,15241,0,0,64,1360,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL 0,15,147 +17 2517 . A <*> 0 . DP=5;I16=3,2,0,0,188,7110,0,0,269,15241,0,0,63,1375,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL 0,15,161 +17 2518 . T <*> 0 . DP=4;I16=2,2,0,0,160,6414,0,0,240,14400,0,0,63,1395,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,146 +17 2519 . C <*> 0 . DP=4;I16=2,2,0,0,136,4734,0,0,240,14400,0,0,63,1419,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,125 +17 2520 . G <*> 0 . DP=3;I16=1,2,0,0,107,3865,0,0,180,10800,0,0,64,1446,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,101 +17 2521 . C <*> 0 . DP=3;I16=1,2,0,0,117,4563,0,0,180,10800,0,0,65,1475,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,111 +17 2522 . A <*> 0 . DP=3;I16=1,2,0,0,121,4883,0,0,180,10800,0,0,66,1506,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,114 +17 2523 . T <*> 0 . DP=3;I16=1,2,0,0,124,5134,0,0,180,10800,0,0,67,1539,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,117 +17 2524 . C <*> 0 . DP=3;I16=1,2,0,0,119,4721,0,0,180,10800,0,0,68,1574,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,112 +17 2525 . A <*> 0 . DP=3;I16=1,2,0,0,124,5126,0,0,180,10800,0,0,69,1611,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,117 +17 2526 . C <*> 0 . DP=3;I16=1,2,0,0,119,4723,0,0,180,10800,0,0,70,1650,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,113 +17 2527 . T <*> 0 . DP=3;I16=1,2,0,0,127,5381,0,0,180,10800,0,0,71,1691,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,119 +17 2528 . G <*> 0 . DP=3;I16=1,2,0,0,127,5379,0,0,180,10800,0,0,72,1734,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,119 +17 2529 . C <*> 0 . DP=3;I16=1,2,0,0,124,5134,0,0,180,10800,0,0,73,1779,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,117 +17 2530 . A <*> 0 . DP=3;I16=1,2,0,0,123,5045,0,0,180,10800,0,0,74,1826,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,116 +17 2531 . T <*> 0 . DP=3;I16=1,2,0,0,129,5553,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,122 +17 2532 . T <*> 0 . DP=3;I16=1,2,0,0,124,5128,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,117 +17 2533 . C <*> 0 . DP=3;I16=1,2,0,0,110,4036,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,104 +17 2534 . C <*> 0 . DP=3;I16=1,2,0,0,116,4494,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,110 +17 2535 . A <*> 0 . DP=3;I16=1,2,0,0,130,5642,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,123 +17 2536 . G <*> 0 . DP=3;I16=1,2,0,0,125,5209,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,117 +17 2537 . C <*> 0 . DP=3;I16=1,2,0,0,122,4962,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,115 +17 2538 . C <*> 0 . DP=4;I16=2,2,0,0,137,4829,0,0,240,14400,0,0,75,1875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,126 +17 2539 . C <*> 0 . DP=4;I16=2,2,0,0,121,3713,0,0,240,14400,0,0,76,1876,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,111 +17 2540 . G <*> 0 . DP=4;I16=2,2,0,0,119,4027,0,0,240,14400,0,0,77,1879,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,110 +17 2541 . G <*> 0 . DP=4;I16=2,2,0,0,153,5891,0,0,240,14400,0,0,78,1884,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,140 +17 2542 . T <*> 0 . DP=4;I16=1,2,0,0,116,4534,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,109 +17 2543 . G <*> 0 . DP=4;I16=2,2,0,0,127,4511,0,0,240,14400,0,0,80,1900,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,117 +17 2544 . A <*> 0 . DP=4;I16=2,2,0,0,143,5367,0,0,240,14400,0,0,81,1911,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,132 +17 2545 . C <*> 0 . DP=4;I16=2,2,0,0,142,5122,0,0,240,14400,0,0,82,1924,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,130 +17 2546 . A <*> 0 . DP=4;I16=2,2,0,0,157,6259,0,0,240,14400,0,0,83,1939,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,144 +17 2547 . G <*> 0 . DP=5;I16=3,2,0,0,169,6215,0,0,300,18000,0,0,84,1956,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,150 +17 2548 . A <*> 0 . DP=5;I16=3,2,0,0,195,7783,0,0,300,18000,0,0,86,1976,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,171 +17 2549 . G <*> 0 . DP=5;I16=3,2,0,0,184,6862,0,0,300,18000,0,0,88,2000,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,160 +17 2550 . T <*> 0 . DP=5;I16=3,2,0,0,167,5995,0,0,300,18000,0,0,89,1979,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,148 +17 2551 . G <*> 0 . DP=5;I16=3,2,0,0,171,6245,0,0,300,18000,0,0,90,1964,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,151 +17 2552 . A <*> 0 . DP=5;I16=3,2,0,0,192,7478,0,0,300,18000,0,0,91,1955,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,168 +17 2553 . G <*> 0 . DP=5;I16=3,2,0,0,162,5456,0,0,300,18000,0,0,92,1952,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,142 +17 2554 . T <*> 0 . DP=5;I16=3,2,0,0,183,6813,0,0,300,18000,0,0,93,1955,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,160 +17 2555 . C <*> 0 . DP=5;I16=3,2,0,0,184,6786,0,0,300,18000,0,0,94,1964,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,159 +17 2556 . A <*> 0 . DP=5;I16=3,2,0,0,168,5758,0,0,300,18000,0,0,95,1979,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,146 +17 2557 . C <*> 0 . DP=5;I16=3,2,0,0,172,6136,0,0,300,18000,0,0,96,2000,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,151 +17 2558 . T <*> 0 . DP=5;I16=3,2,0,0,201,8083,0,0,300,18000,0,0,97,2027,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,174 +17 2559 . G <*> 0 . DP=5;I16=3,2,0,0,179,6487,0,0,300,18000,0,0,98,2060,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,156 +17 2560 . T <*> 0 . DP=5;I16=3,2,0,0,163,5739,0,0,300,18000,0,0,99,2099,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,144 +17 2561 . C <*> 0 . DP=5;I16=3,2,0,0,175,6231,0,0,300,18000,0,0,100,2144,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,153 +17 2562 . T <*> 0 . DP=5;I16=3,2,0,0,190,7478,0,0,300,18000,0,0,101,2195,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,167 +17 2563 . C <*> 0 . DP=5;I16=3,2,0,0,163,5483,0,0,300,18000,0,0,102,2252,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,142 +17 2564 . A G,<*> 0 . DP=5;I16=0,0,2,2,0,0,135,4725,0,0,240,14400,0,0,77,1639;QS=0,1,0;VDB=0.610267;SGB=-0.556411;MQSB=1;MQ0F=0 PL 124,12,0,124,12,124 +17 2565 . A <*> 0 . DP=5;I16=3,2,0,0,191,7347,0,0,300,18000,0,0,102,2280,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,166 +17 2566 . A <*> 0 . DP=5;I16=3,2,0,0,186,6998,0,0,300,18000,0,0,101,2251,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,162 +17 2567 . A <*> 0 . DP=5;I16=3,2,0,0,191,7375,0,0,300,18000,0,0,100,2228,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,166 +17 2568 . A <*> 0 . DP=5;I16=3,2,0,0,192,7418,0,0,300,18000,0,0,99,2211,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,167 +17 2569 . A <*> 0 . DP=5;I16=3,2,0,0,198,7886,0,0,300,18000,0,0,98,2200,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,172 +17 2570 . G <*> 0 . DP=6;I16=4,2,0,0,215,7805,0,0,360,21600,0,0,97,2195,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,176 +17 2571 . A <*> 0 . DP=6;I16=4,2,0,0,186,6058,0,0,360,21600,0,0,97,2197,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,155 +17 2572 . A <*> 0 . DP=6;I16=4,2,0,0,210,7496,0,0,360,21600,0,0,97,2207,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,173 +17 2573 . A <*> 0 . DP=6;I16=4,2,0,0,221,8385,0,0,360,21600,0,0,96,2174,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,183 +17 2574 . G <*> 0 . DP=6;I16=4,2,0,0,213,7745,0,0,360,21600,0,0,95,2147,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,176 +17 2575 . G <*> 0 . DP=5;I16=3,2,0,0,157,5477,0,0,300,18000,0,0,95,2125,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,140 +17 2576 . A <*> 0 . DP=5;I16=2,2,0,0,143,5195,0,0,240,14400,0,0,70,1482,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,131 +17 2577 . A <*> 0 . DP=6;I16=3,2,0,0,176,6532,0,0,300,18000,0,0,70,1468,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,155 +17 2578 . G <*> 0 . DP=6;I16=4,2,0,0,190,6578,0,0,360,21600,0,0,96,2084,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,161 +17 2579 . A <*> 0 . DP=6;I16=4,2,0,0,213,7731,0,0,360,21600,0,0,97,2081,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,176 +17 2580 . A <*> 0 . DP=6;I16=4,2,0,0,205,7169,0,0,360,21600,0,0,98,2084,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,169 +17 2581 . A <*> 0 . DP=6;I16=4,2,0,0,199,6865,0,0,360,21600,0,0,99,2093,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,166 +17 2582 . T <*> 0 . DP=6;I16=4,2,0,0,203,7043,0,0,360,21600,0,0,99,2059,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,168 +17 2583 . A <*> 0 . DP=6;I16=4,2,0,0,218,7974,0,0,360,21600,0,0,99,2033,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,178 +17 2584 . A <*> 0 . DP=6;I16=4,2,0,0,227,8731,0,0,360,21600,0,0,99,2015,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,187 +17 2585 . A <*> 0 . DP=6;I16=4,2,0,0,232,9042,0,0,360,21600,0,0,99,2005,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,190 +17 2586 . G <*> 0 . DP=6;I16=4,2,0,0,213,7767,0,0,360,21600,0,0,99,2003,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,176 +17 2587 . A <*> 0 . DP=6;I16=2,2,0,0,149,5577,0,0,240,14400,0,0,64,1284,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,136 +17 2588 . A <*> 0 . DP=6;I16=4,2,0,0,194,6608,0,0,360,21600,0,0,99,2023,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,162 +17 2589 . A <*> 0 . DP=6;I16=4,2,0,0,204,7256,0,0,360,21600,0,0,99,2045,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,170 +17 2590 . A <*> 0 . DP=6;I16=4,2,0,0,190,6516,0,0,360,21600,0,0,99,2075,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,160 +17 2591 . C <*> 0 . DP=5;I16=4,1,0,0,161,5591,0,0,300,18000,0,0,100,2112,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,136 +17 2592 . A <*> 0 . DP=5;I16=4,1,0,0,166,5884,0,0,300,18000,0,0,101,2155,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,139 +17 2593 . A <*> 0 . DP=5;I16=4,1,0,0,174,6594,0,0,300,18000,0,0,102,2204,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,147 +17 2594 . A <*> 0 . DP=5;I16=4,1,0,0,184,6994,0,0,300,18000,0,0,103,2259,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,153 +17 2595 . T <*> 0 . DP=5;I16=4,1,0,0,172,6154,0,0,300,18000,0,0,104,2320,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,143 +17 2596 . A <*> 0 . DP=5;I16=3,1,0,0,146,5364,0,0,240,14400,0,0,79,1711,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,129 +17 2597 . A <*> 0 . DP=5;I16=4,1,0,0,177,6327,0,0,300,18000,0,0,104,2356,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,145 +17 2598 . A <*> 0 . DP=5;I16=4,1,0,0,194,7596,0,0,300,18000,0,0,104,2380,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,159 +17 2599 . A <*> 0 . DP=5;I16=4,1,0,0,181,6739,0,0,300,18000,0,0,104,2408,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,150 +17 2600 . A <*> 0 . DP=5;I16=4,1,0,0,181,6727,0,0,300,18000,0,0,104,2440,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,150 +17 2601 . T <*> 0 . DP=5;I16=4,1,0,0,172,6068,0,0,300,18000,0,0,104,2476,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,142 +17 2602 . A <*> 0 . DP=6;I16=5,1,0,0,201,6887,0,0,360,21600,0,0,104,2516,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,154 +17 2603 . A <*> 0 . DP=6;I16=5,1,0,0,228,8730,0,0,360,21600,0,0,104,2510,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,172 +17 2604 . T <*> 0 . DP=6;I16=5,1,0,0,199,6861,0,0,360,21600,0,0,104,2508,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,154 +17 2605 . A <*> 0 . DP=6;I16=4,1,0,0,193,7485,0,0,300,18000,0,0,79,1885,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,157 +17 2606 . G <*> 0 . DP=6;I16=4,1,0,0,171,6143,0,0,300,18000,0,0,79,1891,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,142 +17 2607 . T <*> 0 . DP=5;I16=5,0,0,0,187,7009,0,0,300,18000,0,0,105,2525,0,0;QS=1,0;MQ0F=0 PL 0,15,132 +17 2608 . G <*> 0 . DP=5;I16=5,0,0,0,178,6390,0,0,300,18000,0,0,106,2536,0,0;QS=1,0;MQ0F=0 PL 0,15,127 +17 2609 . C <*> 0 . DP=5;I16=5,0,0,0,171,6059,0,0,300,18000,0,0,107,2549,0,0;QS=1,0;MQ0F=0 PL 0,15,124 +17 2610 . A <*> 0 . DP=5;I16=5,0,0,0,167,5737,0,0,300,18000,0,0,108,2564,0,0;QS=1,0;MQ0F=0 PL 0,15,121 +17 2611 . G <*> 0 . DP=5;I16=5,0,0,0,164,5848,0,0,300,18000,0,0,109,2581,0,0;QS=1,0;MQ0F=0 PL 0,15,122 +17 2612 . A <*> 0 . DP=5;I16=4,0,0,0,151,5763,0,0,240,14400,0,0,85,1975,0,0;QS=1,0;MQ0F=0 PL 0,12,117 +17 2613 . C <*> 0 . DP=5;I16=5,0,0,0,165,5651,0,0,300,18000,0,0,111,2621,0,0;QS=1,0;MQ0F=0 PL 0,15,120 +17 2614 . A <*> 0 . DP=5;I16=5,0,0,0,197,7779,0,0,300,18000,0,0,111,2595,0,0;QS=1,0;MQ0F=0 PL 0,15,140 +17 2615 . A <*> 0 . DP=5;I16=5,0,0,0,200,8034,0,0,300,18000,0,0,111,2573,0,0;QS=1,0;MQ0F=0 PL 0,15,142 +17 2616 . A <*> 0 . DP=5;I16=5,0,0,0,201,8187,0,0,300,18000,0,0,111,2555,0,0;QS=1,0;MQ0F=0 PL 0,15,144 +17 2617 . A <*> 0 . DP=5;I16=5,0,0,0,194,7650,0,0,300,18000,0,0,111,2541,0,0;QS=1,0;MQ0F=0 PL 0,15,140 +17 2618 . G <*> 0 . DP=5;I16=5,0,0,0,182,6774,0,0,300,18000,0,0,111,2531,0,0;QS=1,0;MQ0F=0 PL 0,15,132 +17 2619 . G <*> 0 . DP=5;I16=5,0,0,0,174,6262,0,0,300,18000,0,0,111,2525,0,0;QS=1,0;MQ0F=0 PL 0,15,127 +17 2620 . C <*> 0 . DP=5;I16=5,0,0,0,155,5179,0,0,300,18000,0,0,111,2523,0,0;QS=1,0;MQ0F=0 PL 0,15,115 +17 2621 . C <*> 0 . DP=5;I16=5,0,0,0,170,6010,0,0,300,18000,0,0,111,2525,0,0;QS=1,0;MQ0F=0 PL 0,15,124 +17 2622 . T <*> 0 . DP=5;I16=5,0,0,0,181,7187,0,0,300,18000,0,0,111,2531,0,0;QS=1,0;MQ0F=0 PL 0,15,134 +17 2623 . T <*> 0 . DP=5;I16=5,0,0,0,177,6535,0,0,300,18000,0,0,110,2492,0,0;QS=1,0;MQ0F=0 PL 0,15,129 +17 2624 . G <*> 0 . DP=5;I16=5,0,0,0,186,7004,0,0,300,18000,0,0,109,2459,0,0;QS=1,0;MQ0F=0 PL 0,15,133 +17 2625 . A <*> 0 . DP=5;I16=5,0,0,0,186,7126,0,0,300,18000,0,0,108,2432,0,0;QS=1,0;MQ0F=0 PL 0,15,135 +17 2626 . C <*> 0 . DP=5;I16=5,0,0,0,169,5847,0,0,300,18000,0,0,107,2411,0,0;QS=1,0;MQ0F=0 PL 0,15,122 +17 2627 . C <*> 0 . DP=5;I16=5,0,0,0,178,6516,0,0,300,18000,0,0,106,2396,0,0;QS=1,0;MQ0F=0 PL 0,15,129 +17 2628 . C <*> 0 . DP=6;I16=5,0,0,0,172,6304,0,0,300,18000,0,0,94,2236,0,0;QS=1,0;MQ0F=0 PL 0,15,127 +17 2629 . A <*> 0 . DP=6;I16=6,0,0,0,224,8478,0,0,360,21600,0,0,103,2281,0,0;QS=1,0;MQ0F=0 PL 0,18,148 +17 2630 . T <*> 0 . DP=6;I16=6,0,0,0,208,7570,0,0,360,21600,0,0,102,2232,0,0;QS=1,0;MQ0F=0 PL 0,18,140 +17 2631 . C <*> 0 . DP=6;I16=6,0,0,0,212,7674,0,0,360,21600,0,0,101,2189,0,0;QS=1,0;MQ0F=0 PL 0,18,142 +17 2632 . T <*> 0 . DP=6;I16=6,0,0,0,249,10377,0,0,360,21600,0,0,100,2152,0,0;QS=1,0;MQ0F=0 PL 0,18,164 +17 2633 . A <*> 0 . DP=6;I16=6,0,0,0,223,8405,0,0,360,21600,0,0,99,2121,0,0;QS=1,0;MQ0F=0 PL 0,18,148 +17 2634 . G <*> 0 . DP=6;I16=6,0,0,0,225,8531,0,0,360,21600,0,0,98,2096,0,0;QS=1,0;MQ0F=0 PL 0,18,149 +17 2635 . C <*> 0 . DP=6;I16=6,0,0,0,220,8358,0,0,360,21600,0,0,97,2077,0,0;QS=1,0;MQ0F=0 PL 0,18,148 +17 2636 . T <*> 0 . DP=6;I16=6,0,0,0,242,9866,0,0,360,21600,0,0,96,2064,0,0;QS=1,0;MQ0F=0 PL 0,18,160 +17 2637 . T <*> 0 . DP=6;I16=6,0,0,0,215,7859,0,0,360,21600,0,0,95,2057,0,0;QS=1,0;MQ0F=0 PL 0,18,144 +17 2638 . T <*> 0 . DP=6;I16=6,0,0,0,197,6837,0,0,360,21600,0,0,94,2056,0,0;QS=1,0;MQ0F=0 PL 0,18,135 +17 2639 . G <*> 0 . DP=5;I16=5,0,0,0,172,6166,0,0,300,18000,0,0,94,2060,0,0;QS=1,0;MQ0F=0 PL 0,15,125 +17 2640 . G <*> 0 . DP=5;I16=5,0,0,0,156,5470,0,0,300,18000,0,0,94,2068,0,0;QS=1,0;MQ0F=0 PL 0,15,117 +17 2641 . C <*> 0 . DP=5;I16=5,0,0,0,177,6535,0,0,300,18000,0,0,94,2080,0,0;QS=1,0;MQ0F=0 PL 0,15,129 +17 2642 . C <*> 0 . DP=5;I16=5,0,0,0,180,6718,0,0,300,18000,0,0,94,2096,0,0;QS=1,0;MQ0F=0 PL 0,15,131 +17 2643 . C <*> 0 . DP=5;I16=5,0,0,0,183,6947,0,0,300,18000,0,0,94,2116,0,0;QS=1,0;MQ0F=0 PL 0,15,133 +17 2644 . T <*> 0 . DP=5;I16=5,0,0,0,201,8147,0,0,300,18000,0,0,94,2140,0,0;QS=1,0;MQ0F=0 PL 0,15,143 +17 2645 . C <*> 0 . DP=5;I16=4,0,0,0,159,6331,0,0,240,14400,0,0,77,1879,0,0;QS=1,0;MQ0F=0 PL 0,12,122 +17 2646 . A <*> 0 . DP=5;I16=5,0,0,0,177,6489,0,0,300,18000,0,0,93,2151,0,0;QS=1,0;MQ0F=0 PL 0,15,129 +17 2647 . G <*> 0 . DP=5;I16=5,0,0,0,177,6539,0,0,300,18000,0,0,92,2140,0,0;QS=1,0;MQ0F=0 PL 0,15,129 +17 2648 . C <*> 0 . DP=4;I16=4,0,0,0,154,5940,0,0,240,14400,0,0,92,2134,0,0;QS=1,0;MQ0F=0 PL 0,12,118 +17 2649 . A <*> 0 . DP=4;I16=4,0,0,0,131,4745,0,0,240,14400,0,0,92,2132,0,0;QS=1,0;MQ0F=0 PL 0,12,105 +17 2650 . T <*> 0 . DP=4;I16=4,0,0,0,153,5867,0,0,240,14400,0,0,92,2134,0,0;QS=1,0;MQ0F=0 PL 0,12,118 +17 2651 . C <*> 0 . DP=4;I16=4,0,0,0,157,6201,0,0,240,14400,0,0,92,2140,0,0;QS=1,0;MQ0F=0 PL 0,12,121 +17 2652 . A <*> 0 . DP=4;I16=4,0,0,0,164,6736,0,0,240,14400,0,0,92,2150,0,0;QS=1,0;MQ0F=0 PL 0,12,126 +17 2653 . A <*> 0 . DP=4;I16=3,0,0,0,131,5721,0,0,180,10800,0,0,67,1539,0,0;QS=1,0;MQ0F=0 PL 0,9,109 +17 2654 . C <*> 0 . DP=3;I16=3,0,0,0,118,4652,0,0,180,10800,0,0,66,1506,0,0;QS=1,0;MQ0F=0 PL 0,9,99 +17 2655 . C <*> 0 . DP=3;I16=3,0,0,0,114,4334,0,0,180,10800,0,0,65,1475,0,0;QS=1,0;MQ0F=0 PL 0,9,95 +17 2656 . G <*> 0 . DP=3;I16=3,0,0,0,89,2653,0,0,180,10800,0,0,64,1446,0,0;QS=1,0;MQ0F=0 PL 0,9,74 +17 2657 . C <*> 0 . DP=3;I16=3,0,0,0,118,4650,0,0,180,10800,0,0,63,1419,0,0;QS=1,0;MQ0F=0 PL 0,9,99 +17 2658 . T <*> 0 . DP=3;I16=3,0,0,0,128,5466,0,0,180,10800,0,0,62,1394,0,0;QS=1,0;MQ0F=0 PL 0,9,107 +17 2659 . A <*> 0 . DP=3;I16=3,0,0,0,111,4139,0,0,180,10800,0,0,61,1371,0,0;QS=1,0;MQ0F=0 PL 0,9,93 +17 2660 . G <*> 0 . DP=3;I16=3,0,0,0,112,4222,0,0,180,10800,0,0,60,1350,0,0;QS=1,0;MQ0F=0 PL 0,9,94 +17 2661 . A <*> 0 . DP=3;I16=3,0,0,0,124,5130,0,0,180,10800,0,0,59,1331,0,0;QS=1,0;MQ0F=0 PL 0,9,104 +17 2662 . T <*> 0 . DP=3;I16=3,0,0,0,118,4658,0,0,180,10800,0,0,58,1314,0,0;QS=1,0;MQ0F=0 PL 0,9,99 +17 2663 . A <*> 0 . DP=3;I16=3,0,0,0,121,4885,0,0,180,10800,0,0,57,1299,0,0;QS=1,0;MQ0F=0 PL 0,9,101 +17 2664 . C <*> 0 . DP=3;I16=3,0,0,0,109,3969,0,0,180,10800,0,0,56,1286,0,0;QS=1,0;MQ0F=0 PL 0,9,91 +17 2665 . G <*> 0 . DP=3;I16=3,0,0,0,93,2891,0,0,180,10800,0,0,55,1275,0,0;QS=1,0;MQ0F=0 PL 0,9,78 +17 2666 . T <*> 0 . DP=3;I16=3,0,0,0,112,4210,0,0,180,10800,0,0,54,1266,0,0;QS=1,0;MQ0F=0 PL 0,9,94 +17 2667 . C <*> 0 . DP=3;I16=3,0,0,0,117,4587,0,0,180,10800,0,0,53,1259,0,0;QS=1,0;MQ0F=0 PL 0,9,98 +17 2668 . C <*> 0 . DP=3;I16=3,0,0,0,113,4269,0,0,180,10800,0,0,52,1254,0,0;QS=1,0;MQ0F=0 PL 0,9,95 +17 2669 . C <*> 0 . DP=3;I16=3,0,0,0,105,3681,0,0,180,10800,0,0,51,1251,0,0;QS=1,0;MQ0F=0 PL 0,9,88 +17 2670 . T <*> 0 . DP=3;I16=3,0,0,0,119,4741,0,0,180,10800,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,9,100 +17 2671 . C <*> 0 . DP=2;I16=2,0,0,0,77,2965,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,70 +17 2672 . C <*> 0 . DP=2;I16=2,0,0,0,82,3370,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,75 +17 2673 . C <*> 0 . DP=2;I16=2,0,0,0,82,3370,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,75 +17 2674 . T <*> 0 . DP=2;I16=2,0,0,0,87,3785,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,79 +17 2675 . T <*> 0 . DP=2;I16=2,0,0,0,81,3285,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,74 +17 2676 . T <*> 0 . DP=2;I16=2,0,0,0,82,3364,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,75 +17 2677 . C <*> 0 . DP=2;I16=2,0,0,0,84,3530,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQ0F=0 PL 0,6,77 +17 2678 . T <*> 0 . DP=2;I16=2,0,0,0,88,3872,0,0,120,7200,0,0,49,1201,0,0;QS=1,0;MQ0F=0 PL 0,6,80 +17 2679 . T <*> 0 . DP=2;I16=2,0,0,0,82,3364,0,0,120,7200,0,0,48,1154,0,0;QS=1,0;MQ0F=0 PL 0,6,75 +17 2680 . C <*> 0 . DP=2;I16=2,0,0,0,76,2896,0,0,120,7200,0,0,47,1109,0,0;QS=1,0;MQ0F=0 PL 0,6,70 +17 2681 . T <*> 0 . DP=2;I16=2,0,0,0,82,3380,0,0,120,7200,0,0,46,1066,0,0;QS=1,0;MQ0F=0 PL 0,6,75 +17 2682 . G <*> 0 . DP=2;I16=2,0,0,0,70,2458,0,0,120,7200,0,0,45,1025,0,0;QS=1,0;MQ0F=0 PL 0,6,64 +17 2683 . G <*> 0 . DP=2;I16=2,0,0,0,58,1682,0,0,120,7200,0,0,44,986,0,0;QS=1,0;MQ0F=0 PL 0,6,53 +17 2684 . G <*> 0 . DP=2;I16=2,0,0,0,68,2314,0,0,120,7200,0,0,43,949,0,0;QS=1,0;MQ0F=0 PL 0,6,62 +17 2685 . G <*> 0 . DP=2;I16=2,0,0,0,48,1352,0,0,120,7200,0,0,42,914,0,0;QS=1,0;MQ0F=0 PL 0,6,45 +17 2686 . C <*> 0 . DP=2;I16=2,0,0,0,74,2740,0,0,120,7200,0,0,41,881,0,0;QS=1,0;MQ0F=0 PL 0,6,68 +17 2687 . A <*> 0 . DP=2;I16=2,0,0,0,65,2257,0,0,120,7200,0,0,40,850,0,0;QS=1,0;MQ0F=0 PL 0,6,61 +17 2688 . C <*> 0 . DP=2;I16=2,0,0,0,72,2600,0,0,120,7200,0,0,39,821,0,0;QS=1,0;MQ0F=0 PL 0,6,66 +17 2689 . A <*> 0 . DP=2;I16=2,0,0,0,80,3208,0,0,120,7200,0,0,38,794,0,0;QS=1,0;MQ0F=0 PL 0,6,73 +17 2690 . G <*> 0 . DP=2;I16=2,0,0,0,67,2249,0,0,120,7200,0,0,37,769,0,0;QS=1,0;MQ0F=0 PL 0,6,61 +17 2691 . G <*> 0 . DP=2;I16=2,0,0,0,69,2381,0,0,120,7200,0,0,36,746,0,0;QS=1,0;MQ0F=0 PL 0,6,63 +17 2692 . T <*> 0 . DP=2;I16=2,0,0,0,79,3125,0,0,120,7200,0,0,35,725,0,0;QS=1,0;MQ0F=0 PL 0,6,72 +17 2693 . C <*> 0 . DP=2;I16=2,0,0,0,77,2969,0,0,120,7200,0,0,34,706,0,0;QS=1,0;MQ0F=0 PL 0,6,70 +17 2694 . A <*> 0 . DP=2;I16=2,0,0,0,80,3202,0,0,120,7200,0,0,33,689,0,0;QS=1,0;MQ0F=0 PL 0,6,73 +17 2695 . C <*> 0 . DP=2;I16=2,0,0,0,68,2344,0,0,120,7200,0,0,32,674,0,0;QS=1,0;MQ0F=0 PL 0,6,63 +17 2696 . A <*> 0 . DP=2;I16=2,0,0,0,76,2888,0,0,120,7200,0,0,31,661,0,0;QS=1,0;MQ0F=0 PL 0,6,69 +17 2697 . C <*> 0 . DP=2;I16=2,0,0,0,72,2594,0,0,120,7200,0,0,30,650,0,0;QS=1,0;MQ0F=0 PL 0,6,66 +17 2698 . T <*> 0 . DP=3;I16=2,0,0,0,84,3528,0,0,120,7200,0,0,29,641,0,0;QS=1,0;MQ0F=0 PL 0,6,77 +17 2699 . C <*> 0 . DP=3;I16=2,1,0,0,114,4334,0,0,149,8041,0,0,52,1210,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,98 +17 2700 . T <*> 0 . DP=3;I16=2,1,0,0,123,5049,0,0,149,8041,0,0,52,1254,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,105 +17 2701 . C <*> 0 . DP=3;I16=2,1,0,0,100,3394,0,0,149,8041,0,0,51,1251,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,94 +17 2702 . T <*> 0 . DP=3;I16=2,1,0,0,88,2802,0,0,149,8041,0,0,50,1250,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,83 +17 2703 . T <*> 0 . DP=2;I16=1,0,0,0,32,1024,0,0,60,3600,0,0,25,625,0,0;QS=1,0;MQ0F=0 PL 0,3,32 +17 2704 . C <*> 0 . DP=2;I16=1,1,0,0,55,1777,0,0,89,4441,0,0,49,1201,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,55 +17 2705 . C <*> 0 . DP=2;I16=1,1,0,0,56,1666,0,0,89,4441,0,0,48,1154,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,56 +17 2706 . A <*> 0 . DP=2;I16=1,1,0,0,82,3362,0,0,89,4441,0,0,47,1109,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,70 +17 2707 . G <*> 0 . DP=2;I16=1,1,0,0,60,1802,0,0,89,4441,0,0,46,1066,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,60 +17 2708 . G <*> 0 . DP=2;I16=1,1,0,0,57,1665,0,0,89,4441,0,0,45,1025,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,57 +17 2709 . T <*> 0 . DP=2;I16=1,0,0,0,39,1521,0,0,60,3600,0,0,19,361,0,0;QS=1,0;MQ0F=0 PL 0,3,39 +17 2710 . C <*> 0 . DP=2;I16=1,0,0,0,38,1444,0,0,60,3600,0,0,18,324,0,0;QS=1,0;MQ0F=0 PL 0,3,38 +17 2711 . T <*> 0 . DP=2;I16=1,1,0,0,78,3074,0,0,89,4441,0,0,42,914,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,72 +17 2712 . A <*> 0 . DP=2;I16=1,1,0,0,66,2196,0,0,89,4441,0,0,41,881,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,65 +17 2713 . G T,<*> 0 . DP=2;I16=1,0,0,1,37,1369,14,196,60,3600,29,841,15,225,25,625;QS=0.72549,0.27451,0;SGB=-0.379885;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL 8,0,31,11,34,42 +17 2714 . G <*> 0 . DP=2;I16=1,1,0,0,65,2125,0,0,89,4441,0,0,39,821,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,64 +17 2715 . A <*> 0 . DP=2;I16=1,1,0,0,63,2069,0,0,89,4441,0,0,38,794,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,63 +17 2716 . T <*> 0 . DP=3;I16=1,2,0,0,95,3097,0,0,149,8041,0,0,37,769,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,90 +17 2717 . G <*> 0 . DP=3;I16=1,1,0,0,72,2592,0,0,120,7200,0,0,12,122,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,72 +17 2718 . C <*> 0 . DP=3;I16=1,1,0,0,65,2153,0,0,120,7200,0,0,12,104,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,65 +17 2719 . A <*> 0 . DP=3;I16=1,2,0,0,115,4427,0,0,149,8041,0,0,37,715,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,99 +17 2720 . G <*> 0 . DP=3;I16=1,2,0,0,108,3902,0,0,149,8041,0,0,37,705,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,97 +17 2721 . C <*> 0 . DP=3;I16=1,1,0,0,76,2888,0,0,120,7200,0,0,12,74,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,76 +17 2722 . T <*> 0 . DP=3;I16=1,2,0,0,112,4194,0,0,149,8041,0,0,37,697,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,98 +17 2723 . G <*> 0 . DP=3;I16=1,2,0,0,80,2254,0,0,149,8041,0,0,37,699,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,76 +17 2724 . A <*> 0 . DP=3;I16=1,2,0,0,91,2877,0,0,149,8041,0,0,37,705,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,84 +17 2725 . G <*> 0 . DP=3;I16=1,1,0,0,67,2257,0,0,120,7200,0,0,12,90,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,67 +17 2726 . G <*> 0 . DP=3;I16=0,2,0,0,50,1282,0,0,89,4441,0,0,35,725,0,0;QS=1,0;MQ0F=0 PL 0,6,46 +17 2727 . G <*> 0 . DP=2;I16=0,2,0,0,65,2113,0,0,89,4441,0,0,36,746,0,0;QS=1,0;MQ0F=0 PL 0,6,56 +17 2728 . G <*> 0 . DP=2;I16=0,2,0,0,53,1549,0,0,89,4441,0,0,37,769,0,0;QS=1,0;MQ0F=0 PL 0,6,50 +17 2729 . T <*> 0 . DP=2;I16=0,2,0,0,75,2813,0,0,89,4441,0,0,38,794,0,0;QS=1,0;MQ0F=0 PL 0,6,62 +17 2730 . G <*> 0 . DP=2;I16=0,2,0,0,52,1640,0,0,89,4441,0,0,39,821,0,0;QS=1,0;MQ0F=0 PL 0,6,49 +17 2731 . C <*> 0 . DP=2;I16=0,2,0,0,57,1637,0,0,89,4441,0,0,40,850,0,0;QS=1,0;MQ0F=0 PL 0,6,52 +17 2732 . C <*> 0 . DP=2;I16=0,2,0,0,41,881,0,0,89,4441,0,0,41,881,0,0;QS=1,0;MQ0F=0 PL 0,6,38 +17 2733 . C A,<*> 0 . DP=2;I16=0,1,0,1,24,576,13,169,60,3600,29,841,17,289,25,625;QS=0.648649,0.351351,0;SGB=-0.379885;RPB=1;MQB=1;BQB=1;MQ0F=0 PL 7,0,18,10,21,28 +17 2734 . C <*> 0 . DP=2;I16=0,1,0,0,39,1521,0,0,60,3600,0,0,18,324,0,0;QS=1,0;MQ0F=0 PL 0,3,39 +17 2735 . T <*> 0 . DP=2;I16=0,1,0,0,41,1681,0,0,60,3600,0,0,19,361,0,0;QS=1,0;MQ0F=0 PL 0,3,41 +17 2736 . C <*> 0 . DP=2;I16=0,1,0,0,33,1089,0,0,60,3600,0,0,20,400,0,0;QS=1,0;MQ0F=0 PL 0,3,33 +17 2737 . T <*> 0 . DP=2;I16=0,2,0,0,69,2441,0,0,89,4441,0,0,46,1066,0,0;QS=1,0;MQ0F=0 PL 0,6,64 +17 2738 . T <*> 0 . DP=2;I16=0,2,0,0,50,1492,0,0,89,4441,0,0,47,1109,0,0;QS=1,0;MQ0F=0 PL 0,6,47 +17 2739 . A <*> 0 . DP=3;I16=1,2,0,0,82,2402,0,0,149,8041,0,0,48,1154,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,78 +17 2740 . C <*> 0 . DP=3;I16=1,1,0,0,71,2521,0,0,120,7200,0,0,25,577,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,71 +17 2741 . C <*> 0 . DP=3;I16=1,1,0,0,75,2817,0,0,120,7200,0,0,27,629,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,75 +17 2742 . A <*> 0 . DP=3;I16=1,2,0,0,96,3288,0,0,149,8041,0,0,53,1259,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,92 +17 2743 . T <*> 0 . DP=3;I16=1,2,0,0,104,3672,0,0,149,8041,0,0,54,1266,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,99 +17 2744 . C <*> 0 . DP=3;I16=1,1,0,0,76,2888,0,0,120,7200,0,0,30,650,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,76 +17 2745 . T <*> 0 . DP=3;I16=1,2,0,0,109,4125,0,0,149,8041,0,0,56,1286,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,104 +17 2746 . A <*> 0 . DP=3;I16=1,1,0,0,78,3042,0,0,120,7200,0,0,32,674,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,78 +17 2747 . A <*> 0 . DP=3;I16=1,2,0,0,100,3686,0,0,149,8041,0,0,58,1314,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,96 +17 2748 . T <*> 0 . DP=3;I16=1,2,0,0,119,4723,0,0,149,8041,0,0,59,1331,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,103 +17 2749 . C <*> 0 . DP=3;I16=1,2,0,0,107,3837,0,0,149,8041,0,0,60,1350,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,98 +17 2750 . T <*> 0 . DP=4;I16=2,2,0,0,141,5111,0,0,209,11641,0,0,61,1371,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,12,130 +17 2751 . G <*> 0 . DP=4;I16=2,1,0,0,109,3993,0,0,180,10800,0,0,38,770,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,103 +17 2752 . T <*> 0 . DP=4;I16=2,2,0,0,130,4356,0,0,209,11641,0,0,63,1327,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,12,119 +17 2753 . G <*> 0 . DP=4;I16=2,2,0,0,126,4374,0,0,209,11641,0,0,64,1314,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,12,116 +17 2754 . C <*> 0 . DP=4;I16=2,1,0,0,110,4108,0,0,180,10800,0,0,44,866,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,104 +17 2755 . C <*> 0 . DP=4;I16=2,1,0,0,103,3709,0,0,180,10800,0,0,46,906,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,97 +17 2756 . C <*> 0 . DP=4;I16=2,1,0,0,103,3709,0,0,180,10800,0,0,48,950,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,97 +17 2757 . T <*> 0 . DP=5;I16=3,2,0,0,168,6208,0,0,269,15241,0,0,68,1322,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,15,147 +17 2758 . T <*> 0 . DP=5;I16=3,1,0,0,152,5794,0,0,240,14400,0,0,53,1051,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,133 +17 2759 . A <*> 0 . DP=5;I16=3,2,0,0,170,5970,0,0,269,15241,0,0,72,1366,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,15,147 +17 2760 . T <*> 0 . DP=5;I16=3,2,0,0,172,6448,0,0,269,15241,0,0,74,1400,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,15,150 +17 2761 . T <*> 0 . DP=5;I16=3,1,0,0,161,6489,0,0,240,14400,0,0,62,1246,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,141 +17 2762 . T <*> 0 . DP=6;I16=3,3,0,0,210,7698,0,0,329,18841,0,0,78,1492,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,177 +17 2763 . C A,<*> 0 . DP=6;I16=3,2,0,1,182,6872,13,169,300,18000,29,841,69,1407,12,144;QS=0.933333,0.0666667,0;SGB=-0.379885;RPB=1;MQB=1;MQSB=0.861511;BQB=1;MQ0F=0 PL 0,5,147,15,150,153 +17 2764 . C <*> 0 . DP=6;I16=3,2,0,0,185,6991,0,0,300,18000,0,0,73,1499,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,162 +17 2765 . T <*> 0 . DP=6;I16=3,3,0,0,223,8627,0,0,329,18841,0,0,86,1648,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,189 +17 2766 . C <*> 0 . DP=7;I16=3,3,0,0,221,8263,0,0,360,21600,0,0,79,1603,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,186 +17 2767 . T <*> 0 . DP=7;I16=3,4,0,0,270,10618,0,0,389,22441,0,0,91,1729,0,0;QS=1,0;MQSB=0.810265;MQ0F=0 PL 0,21,217 +17 2768 . G <*> 0 . DP=7;I16=3,3,0,0,236,9290,0,0,360,21600,0,0,87,1735,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,197 +17 2769 . C <*> 0 . DP=7;I16=3,4,0,0,247,9349,0,0,389,22441,0,0,97,1849,0,0;QS=1,0;MQSB=0.810265;MQ0F=0 PL 0,21,202 +17 2770 . T <*> 0 . DP=7;I16=3,4,0,0,244,9040,0,0,389,22441,0,0,100,1924,0,0;QS=1,0;MQSB=0.810265;MQ0F=0 PL 0,21,199 +17 2771 . T <*> 0 . DP=7;I16=3,3,0,0,241,9731,0,0,329,18841,0,0,98,1984,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,198 +17 2772 . T <*> 0 . DP=7;I16=3,4,0,0,263,10013,0,0,389,22441,0,0,106,2104,0,0;QS=1,0;MQSB=0.810265;MQ0F=0 PL 0,21,210 +17 2773 . A <*> 0 . DP=7;I16=3,4,0,0,258,9904,0,0,389,22441,0,0,109,2209,0,0;QS=1,0;MQSB=0.810265;MQ0F=0 PL 0,21,209 +17 2774 . G <*> 0 . DP=7;I16=3,4,0,0,256,9640,0,0,389,22441,0,0,112,2324,0,0;QS=1,0;MQSB=0.810265;MQ0F=0 PL 0,21,207 +17 2775 . T <*> 0 . DP=7;I16=3,4,0,0,250,9404,0,0,389,22441,0,0,115,2449,0,0;QS=1,0;MQSB=0.810265;MQ0F=0 PL 0,21,203 +17 2776 . G <*> 0 . DP=7;I16=4,3,0,0,262,9920,0,0,420,25200,0,0,118,2532,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,210 +17 2777 . A <*> 0 . DP=7;I16=4,3,0,0,274,10954,0,0,420,25200,0,0,122,2622,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,220 +17 2778 . G <*> 0 . DP=7;I16=4,3,0,0,280,11260,0,0,420,25200,0,0,126,2720,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,224 +17 2779 . G <*> 0 . DP=7;I16=4,3,0,0,272,10726,0,0,420,25200,0,0,130,2826,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,219 +17 2780 . A <*> 0 . DP=7;I16=4,3,0,0,267,10351,0,0,420,25200,0,0,134,2940,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,215 +17 2781 . A <*> 0 . DP=7;I16=4,3,0,0,293,12297,0,0,420,25200,0,0,138,3062,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,233 +17 2782 . G <*> 0 . DP=7;I16=4,3,0,0,270,10624,0,0,420,25200,0,0,142,3192,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,218 +17 2783 . A <*> 0 . DP=7;I16=4,3,0,0,288,11892,0,0,420,25200,0,0,145,3279,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,230 +17 2784 . G <*> 0 . DP=7;I16=4,3,0,0,262,10226,0,0,420,25200,0,0,148,3372,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,212 +17 2785 . G <*> 0 . DP=7;I16=4,3,0,0,254,9338,0,0,420,25200,0,0,151,3471,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,204 +17 2786 . C <*> 0 . DP=7;I16=4,3,0,0,247,8929,0,0,420,25200,0,0,154,3576,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,199 +17 2787 . C <*> 0 . DP=7;I16=4,3,0,0,248,9258,0,0,420,25200,0,0,157,3687,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,200 +17 2788 . C <*> 0 . DP=7;I16=4,3,0,0,261,10047,0,0,420,25200,0,0,159,3753,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,209 +17 2789 . C <*> 0 . DP=7;I16=4,3,0,0,281,11407,0,0,420,25200,0,0,161,3823,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,226 +17 2790 . T <*> 0 . DP=7;I16=4,3,0,0,284,11656,0,0,420,25200,0,0,163,3897,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,227 +17 2791 . G <*> 0 . DP=7;I16=4,3,0,0,281,11305,0,0,420,25200,0,0,165,3975,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,226 +17 2792 . G <*> 0 . DP=7;I16=4,3,0,0,275,10919,0,0,420,25200,0,0,165,3957,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,221 +17 2793 . T <*> 0 . DP=7;I16=4,3,0,0,268,10326,0,0,420,25200,0,0,165,3943,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,214 +17 2794 . C <*> 0 . DP=7;I16=4,3,0,0,251,9369,0,0,420,25200,0,0,165,3933,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,201 +17 2795 . C <*> 0 . DP=7;I16=4,3,0,0,276,10948,0,0,420,25200,0,0,165,3927,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,222 +17 2796 . A <*> 0 . DP=7;I16=4,3,0,0,263,10027,0,0,420,25200,0,0,165,3925,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,211 +17 2797 . T <*> 0 . DP=7;I16=4,3,0,0,267,10287,0,0,420,25200,0,0,165,3927,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,214 +17 2798 . G <*> 0 . DP=7;I16=4,3,0,0,257,9639,0,0,420,25200,0,0,165,3933,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,205 +17 2799 . A <*> 0 . DP=7;I16=4,3,0,0,271,10671,0,0,420,25200,0,0,165,3943,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,218 +17 2800 . A <*> 0 . DP=7;I16=4,3,0,0,295,12483,0,0,420,25200,0,0,165,3957,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,237 +17 2801 . G <*> 0 . DP=7;I16=4,3,0,0,267,10359,0,0,420,25200,0,0,165,3975,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,214 +17 2802 . G <*> 0 . DP=7;I16=4,3,0,0,268,10456,0,0,420,25200,0,0,164,3946,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,215 +17 2803 . G <*> 0 . DP=7;I16=4,3,0,0,258,9786,0,0,420,25200,0,0,163,3919,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,207 +17 2804 . G <*> 0 . DP=7;I16=4,3,0,0,261,9987,0,0,420,25200,0,0,162,3894,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,210 +17 2805 . C <*> 0 . DP=7;I16=4,3,0,0,257,9817,0,0,420,25200,0,0,161,3871,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,205 +17 2806 . C <*> 0 . DP=7;I16=4,2,0,0,233,9191,0,0,360,21600,0,0,150,3750,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,191 +17 2807 . T <*> 0 . DP=7;I16=4,3,0,0,283,11571,0,0,420,25200,0,0,159,3831,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,227 +17 2808 . T <*> 0 . DP=7;I16=4,3,0,0,281,11323,0,0,420,25200,0,0,158,3814,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,225 +17 2809 . T <*> 0 . DP=7;I16=4,3,0,0,282,11432,0,0,420,25200,0,0,157,3799,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,226 +17 2810 . C <*> 0 . DP=7;I16=4,3,0,0,268,10534,0,0,420,25200,0,0,156,3786,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,215 +17 2811 . A <*> 0 . DP=7;I16=4,3,0,0,286,11696,0,0,420,25200,0,0,155,3775,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,228 +17 2812 . G <*> 0 . DP=7;I16=4,3,0,0,270,10622,0,0,420,25200,0,0,154,3766,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,216 +17 2813 . A <*> 0 . DP=7;I16=4,3,0,0,270,10708,0,0,420,25200,0,0,153,3759,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,217 +17 2814 . G <*> 0 . DP=7;I16=4,3,0,0,253,9497,0,0,420,25200,0,0,152,3754,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,204 +17 2815 . A <*> 0 . DP=7;I16=4,3,0,0,258,10102,0,0,420,25200,0,0,150,3702,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,208 +17 2816 . C <*> 0 . DP=7;I16=4,3,0,0,225,8035,0,0,420,25200,0,0,148,3654,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,180 +17 2817 . G <*> 0 . DP=7;I16=4,3,0,0,223,7125,0,0,420,25200,0,0,147,3609,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,178 +17 2818 . G <*> 0 . DP=7;I16=4,3,0,0,256,9514,0,0,420,25200,0,0,147,3567,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,206 +17 2819 . G <*> 0 . DP=7;I16=4,3,0,0,242,8588,0,0,420,25200,0,0,147,3529,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,195 +17 2820 . G <*> 0 . DP=7;I16=4,3,0,0,234,8150,0,0,420,25200,0,0,147,3495,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,188 +17 2821 . A <*> 0 . DP=8;I16=4,3,0,0,210,6834,0,0,420,25200,0,0,147,3465,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,171 +17 2822 . C <*> 0 . DP=8;I16=3,4,0,0,207,6437,0,0,420,25200,0,0,155,3775,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,168 +17 2823 . C <*> 0 . DP=8;I16=4,3,0,0,240,8298,0,0,420,25200,0,0,147,3417,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,192 +17 2824 . C <*> 0 . DP=8;I16=4,3,0,0,265,10049,0,0,420,25200,0,0,147,3399,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,210 +17 2825 . C <*> 0 . DP=8;I16=4,4,0,0,267,9391,0,0,480,28800,0,0,172,4010,0,0;QS=1,0;MQSB=0.992367;MQ0F=0 PL 0,24,208 +17 2826 . T <*> 0 . DP=8;I16=4,4,0,0,286,10300,0,0,480,28800,0,0,171,3951,0,0;QS=1,0;MQSB=0.992367;MQ0F=0 PL 0,24,220 +17 2827 . G <*> 0 . DP=8;I16=4,4,0,0,273,9663,0,0,480,28800,0,0,170,3898,0,0;QS=1,0;MQSB=0.992367;MQ0F=0 PL 0,24,214 +17 2828 . A <*> 0 . DP=9;I16=4,4,0,0,280,10170,0,0,480,28800,0,0,169,3851,0,0;QS=1,0;MQSB=0.992367;MQ0F=0 PL 0,24,219 +17 2829 . G <*> 0 . DP=9;I16=4,5,0,0,307,10597,0,0,540,32400,0,0,169,3811,0,0;QS=1,0;MQSB=0.974597;MQ0F=0 PL 0,27,227 +17 2830 . G <*> 0 . DP=9;I16=4,5,0,0,293,10083,0,0,540,32400,0,0,169,3779,0,0;QS=1,0;MQSB=0.974597;MQ0F=0 PL 0,27,222 +17 2831 . A <*> 0 . DP=10;I16=5,5,0,0,353,12747,0,0,600,36000,0,0,169,3755,0,0;QS=1,0;MQSB=0.952347;MQ0F=0 PL 0,30,254 +17 2832 . G <*> 0 . DP=10;I16=5,4,0,0,301,10277,0,0,540,32400,0,0,145,3115,0,0;QS=1,0;MQSB=0.974597;MQ0F=0 PL 0,27,223 +17 2833 . C <*> 0 . DP=10;I16=5,5,0,0,363,13247,0,0,600,36000,0,0,170,3686,0,0;QS=1,0;MQSB=0.952347;MQ0F=0 PL 0,30,255 +17 2834 . C <*> 0 . DP=10;I16=5,5,0,0,340,11906,0,0,600,36000,0,0,170,3644,0,0;QS=1,0;MQSB=0.952347;MQ0F=0 PL 0,30,243 +17 2835 . C <*> 0 . DP=10;I16=5,4,0,0,317,11427,0,0,540,32400,0,0,145,2989,0,0;QS=1,0;MQSB=0.974597;MQ0F=0 PL 0,27,235 +17 2836 . C <*> 0 . DP=10;I16=5,4,0,0,271,8799,0,0,540,32400,0,0,145,2971,0,0;QS=1,0;MQSB=0.974597;MQ0F=0 PL 0,27,200 +17 2837 . G <*> 0 . DP=10;I16=4,5,0,0,253,7767,0,0,540,32400,0,0,168,3586,0,0;QS=1,0;MQSB=0.974597;MQ0F=0 PL 0,27,193 +17 2838 . A <*> 0 . DP=9;I16=4,5,0,0,290,9988,0,0,540,32400,0,0,168,3546,0,0;QS=1,0;MQSB=0.974597;MQ0F=0 PL 0,27,220 +17 2839 . G <*> 0 . DP=9;I16=4,4,0,0,274,9520,0,0,480,28800,0,0,143,2893,0,0;QS=1,0;MQSB=0.992367;MQ0F=0 PL 0,24,212 +17 2840 . C <*> 0 . DP=9;I16=4,5,0,0,304,10652,0,0,540,32400,0,0,168,3502,0,0;QS=1,0;MQSB=0.974597;MQ0F=0 PL 0,27,227 +17 2841 . A <*> 0 . DP=9;I16=4,4,0,0,299,11535,0,0,480,28800,0,0,143,2873,0,0;QS=1,0;MQSB=0.992367;MQ0F=0 PL 0,24,234 +17 2842 . G <*> 0 . DP=9;I16=4,5,0,0,310,11124,0,0,540,32400,0,0,165,3361,0,0;QS=1,0;MQSB=0.974597;MQ0F=0 PL 0,27,233 +17 2843 . C <*> 0 . DP=9;I16=4,4,0,0,272,9452,0,0,480,28800,0,0,140,2754,0,0;QS=1,0;MQSB=0.992367;MQ0F=0 PL 0,24,211 +17 2844 . A <*> 0 . DP=9;I16=4,5,0,0,310,11088,0,0,540,32400,0,0,159,3129,0,0;QS=1,0;MQSB=0.974597;MQ0F=0 PL 0,27,231 +17 2845 . G <*> 0 . DP=9;I16=4,4,0,0,296,11044,0,0,480,28800,0,0,136,2634,0,0;QS=1,0;MQSB=0.992367;MQ0F=0 PL 0,24,228 +17 2846 . C <*> 0 . DP=9;I16=4,4,0,0,281,10089,0,0,480,28800,0,0,133,2553,0,0;QS=1,0;MQSB=0.992367;MQ0F=0 PL 0,24,218 +17 2847 . C <*> 0 . DP=9;I16=3,5,0,0,239,7669,0,0,480,28800,0,0,140,2786,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,187 +17 2848 . G <*> 0 . DP=9;I16=3,5,0,0,249,7975,0,0,480,28800,0,0,138,2752,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,191 +17 2849 . T <*> 0 . DP=9;I16=3,6,0,0,300,10676,0,0,540,32400,0,0,152,2986,0,0;QS=1,0;MQSB=0.924584;MQ0F=0 PL 0,27,214 +17 2850 . C <*> 0 . DP=9;I16=3,6,0,0,259,7743,0,0,540,32400,0,0,151,3009,0,0;QS=1,0;MQSB=0.924584;MQ0F=0 PL 0,27,188 +17 2851 . G <*> 0 . DP=8;I16=2,6,0,0,267,9099,0,0,480,28800,0,0,151,3045,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,194 +17 2852 . T <*> 0 . DP=8;I16=2,6,0,0,296,11088,0,0,480,28800,0,0,150,3044,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,214 +17 2853 . G <*> 0 . DP=8;I16=2,6,0,0,281,9945,0,0,480,28800,0,0,149,3057,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,202 +17 2854 . T <*> 0 . DP=8;I16=2,6,0,0,283,10257,0,0,480,28800,0,0,147,3033,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,207 +17 2855 . C <*> 0 . DP=8;I16=2,5,0,0,235,8283,0,0,420,25200,0,0,135,2921,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,185 +17 2856 . T <*> 0 . DP=8;I16=2,3,0,0,191,7471,0,0,300,18000,0,0,86,1786,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,167 +17 2857 . C <*> 0 . DP=8;I16=2,5,0,0,235,8243,0,0,420,25200,0,0,132,2918,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,185 +17 2858 . A <*> 0 . DP=8;I16=2,5,0,0,235,8271,0,0,420,25200,0,0,130,2904,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,185 +17 2859 . C <*> 0 . DP=8;I16=2,6,0,0,258,8962,0,0,480,28800,0,0,133,2883,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,194 +17 2860 . C <*> 0 . DP=8;I16=2,6,0,0,267,9449,0,0,480,28800,0,0,129,2821,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,200 +17 2861 . C <*> 0 . DP=8;I16=2,5,0,0,263,9979,0,0,420,25200,0,0,100,2142,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,203 +17 2862 . A <*> 0 . DP=8;I16=2,6,0,0,311,12199,0,0,480,28800,0,0,121,2721,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,225 +17 2863 . G <*> 0 . DP=7;I16=2,5,0,0,250,9198,0,0,420,25200,0,0,118,2682,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,195 +17 2864 . G <*> 0 . DP=7;I16=2,4,0,0,223,8495,0,0,360,21600,0,0,114,2648,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,185 +17 2865 . G <*> 0 . DP=7;I16=2,5,0,0,244,9016,0,0,420,25200,0,0,112,2622,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,193 +17 2866 . T <*> 0 . DP=6;I16=1,4,0,0,179,6567,0,0,300,18000,0,0,100,2500,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,147 +17 2867 . G <*> 0 . DP=5;I16=2,3,0,0,172,6102,0,0,300,18000,0,0,109,2581,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,150 +17 2868 . T <*> 0 . DP=5;I16=2,3,0,0,179,6849,0,0,300,18000,0,0,108,2564,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,157 +17 2869 . C <*> 0 . DP=5;I16=2,3,0,0,189,7277,0,0,300,18000,0,0,107,2549,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,165 +17 2870 . T <*> 0 . DP=5;I16=2,3,0,0,203,8273,0,0,300,18000,0,0,106,2536,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,176 +17 2871 . G <*> 0 . DP=5;I16=2,3,0,0,197,7851,0,0,300,18000,0,0,105,2525,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,172 +17 2872 . A <*> 0 . DP=5;I16=2,3,0,0,196,7770,0,0,300,18000,0,0,104,2516,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,171 +17 2873 . A <*> 0 . DP=5;I16=2,3,0,0,180,6868,0,0,300,18000,0,0,103,2509,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,159 +17 2874 . A <*> 0 . DP=5;I16=2,3,0,0,183,7197,0,0,300,18000,0,0,102,2504,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,162 +17 2875 . C <*> 0 . DP=5;I16=2,3,0,0,189,7331,0,0,300,18000,0,0,101,2501,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,166 +17 2876 . A <*> 0 . DP=5;I16=2,3,0,0,212,9064,0,0,300,18000,0,0,100,2500,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,185 +17 2877 . G <*> 0 . DP=4;I16=1,3,0,0,168,7062,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,148 +17 2878 . A <*> 0 . DP=5;I16=2,3,0,0,190,7328,0,0,300,18000,0,0,100,2500,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,166 +17 2879 . T <*> 0 . DP=5;I16=2,3,0,0,201,8105,0,0,300,18000,0,0,101,2501,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,175 +17 2880 . G <*> 0 . DP=5;I16=2,3,0,0,199,7949,0,0,300,18000,0,0,102,2504,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,173 +17 2881 . T <*> 0 . DP=5;I16=2,3,0,0,204,8342,0,0,300,18000,0,0,103,2509,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,178 +17 2882 . G <*> 0 . DP=5;I16=2,3,0,0,202,8206,0,0,300,18000,0,0,104,2516,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,176 +17 2883 . G <*> 0 . DP=5;I16=2,3,0,0,201,8159,0,0,300,18000,0,0,105,2525,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,175 +17 2884 . A <*> 0 . DP=5;I16=2,3,0,0,208,8710,0,0,300,18000,0,0,106,2536,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,181 +17 2885 . G <*> 0 . DP=5;I16=2,3,0,0,209,8767,0,0,300,18000,0,0,107,2549,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,182 +17 2886 . G <*> 0 . DP=5;I16=2,3,0,0,196,7708,0,0,300,18000,0,0,108,2564,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,171 +17 2887 . T <*> 0 . DP=5;I16=2,3,0,0,191,7497,0,0,300,18000,0,0,109,2581,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,166 +17 2888 . C <*> 0 . DP=5;I16=2,3,0,0,182,6796,0,0,300,18000,0,0,110,2600,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,159 +17 2889 . T <*> 0 . DP=5;I16=2,3,0,0,201,8119,0,0,300,18000,0,0,111,2621,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,175 +17 2890 . C <*> 0 . DP=5;I16=2,3,0,0,157,5391,0,0,300,18000,0,0,112,2644,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,139 +17 2891 . G <*> 0 . DP=5;I16=2,3,0,0,165,5981,0,0,300,18000,0,0,113,2669,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,143 +17 2892 . G <*> 0 . DP=5;I16=2,3,0,0,188,7126,0,0,300,18000,0,0,114,2696,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,164 +17 2893 . G <*> 0 . DP=5;I16=2,3,0,0,172,6100,0,0,300,18000,0,0,114,2676,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,150 +17 2894 . T <*> 0 . DP=5;I16=2,3,0,0,179,6531,0,0,300,18000,0,0,114,2660,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,155 +17 2895 . G <*> 0 . DP=5;I16=2,3,0,0,190,7324,0,0,300,18000,0,0,114,2648,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,166 +17 2896 . A <*> 0 . DP=5;I16=2,3,0,0,187,7201,0,0,300,18000,0,0,114,2640,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,163 +17 2897 . G <*> 0 . DP=5;I16=2,3,0,0,193,7527,0,0,300,18000,0,0,114,2636,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,168 +17 2898 . G <*> 0 . DP=5;I16=2,3,0,0,194,7564,0,0,300,18000,0,0,114,2636,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,169 +17 2899 . C <*> 0 . DP=5;I16=2,3,0,0,169,5839,0,0,300,18000,0,0,114,2640,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,147 +17 2900 . G <*> 0 . DP=5;I16=2,3,0,0,176,6306,0,0,300,18000,0,0,114,2648,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,153 +17 2901 . T <*> 0 . DP=5;I16=2,3,0,0,190,7286,0,0,300,18000,0,0,114,2660,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,166 +17 2902 . G <*> 0 . DP=5;I16=2,3,0,0,188,7170,0,0,300,18000,0,0,114,2676,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,164 +17 2903 . G <*> 0 . DP=5;I16=2,3,0,0,192,7422,0,0,300,18000,0,0,114,2696,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,168 +17 2904 . C <*> 0 . DP=5;I16=2,3,0,0,195,7621,0,0,300,18000,0,0,112,2620,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,169 +17 2905 . T <*> 0 . DP=5;I16=2,3,0,0,200,8024,0,0,300,18000,0,0,110,2548,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,174 +17 2906 . C <*> 0 . DP=5;I16=2,3,0,0,200,8014,0,0,300,18000,0,0,108,2480,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,173 +17 2907 . A <*> 0 . DP=5;I16=2,3,0,0,195,7791,0,0,300,18000,0,0,105,2367,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,170 +17 2908 . G <*> 0 . DP=5;I16=2,3,0,0,189,7275,0,0,300,18000,0,0,102,2260,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,164 +17 2909 . A <*> 0 . DP=5;I16=2,3,0,0,197,7791,0,0,300,18000,0,0,98,2110,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,171 +17 2910 . T <*> 0 . DP=6;I16=2,3,0,0,192,7376,0,0,300,18000,0,0,94,1968,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,166 +17 2911 . A <*> 0 . DP=6;I16=2,4,0,0,232,8982,0,0,360,21600,0,0,115,2459,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,188 +17 2912 . C <*> 0 . DP=6;I16=2,4,0,0,231,8921,0,0,360,21600,0,0,111,2333,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,189 +17 2913 . A <*> 0 . DP=6;I16=2,4,0,0,243,9863,0,0,360,21600,0,0,107,2215,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,199 +17 2914 . G <*> 0 . DP=6;I16=2,4,0,0,229,8783,0,0,360,21600,0,0,103,2105,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,187 +17 2915 . G <*> 0 . DP=6;I16=2,4,0,0,215,7917,0,0,360,21600,0,0,99,2003,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,178 +17 2916 . G <*> 0 . DP=6;I16=2,3,0,0,178,6430,0,0,300,18000,0,0,70,1284,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,155 +17 2917 . A <*> 0 . DP=6;I16=2,4,0,0,216,7940,0,0,360,21600,0,0,91,1823,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,178 +17 2918 . G <*> 0 . DP=6;I16=3,3,0,0,202,6878,0,0,360,21600,0,0,88,1744,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,170 +17 2919 . T <*> 0 . DP=6;I16=3,3,0,0,211,7509,0,0,360,21600,0,0,86,1672,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,178 +17 2920 . G <*> 0 . DP=6;I16=3,3,0,0,216,7790,0,0,360,21600,0,0,84,1608,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,180 +17 2921 . G <*> 0 . DP=6;I16=3,3,0,0,209,7351,0,0,360,21600,0,0,82,1552,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,176 +17 2922 . C <*> 0 . DP=6;I16=3,3,0,0,205,7125,0,0,360,21600,0,0,80,1504,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,172 +17 2923 . C <*> 0 . DP=6;I16=3,3,0,0,208,7312,0,0,360,21600,0,0,78,1464,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,175 +17 2924 . C <*> 0 . DP=6;I16=3,3,0,0,219,8075,0,0,360,21600,0,0,76,1432,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,184 +17 2925 . A <*> 0 . DP=6;I16=3,3,0,0,226,8516,0,0,360,21600,0,0,74,1408,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,189 +17 2926 . C <*> 0 . DP=6;I16=3,3,0,0,209,7307,0,0,360,21600,0,0,72,1392,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,174 +17 2927 . A <*> 0 . DP=6;I16=3,3,0,0,227,8675,0,0,360,21600,0,0,70,1384,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,191 +17 2928 . G <*> 0 . DP=6;I16=3,3,0,0,192,6208,0,0,360,21600,0,0,68,1384,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,161 +17 2929 . C <*> 0 . DP=5;I16=3,2,0,0,171,6015,0,0,300,18000,0,0,67,1391,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,149 +17 2930 . T <*> 0 . DP=5;I16=3,2,0,0,180,6622,0,0,300,18000,0,0,66,1404,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,157 +17 2931 . C <*> 0 . DP=5;I16=3,2,0,0,161,5367,0,0,300,18000,0,0,65,1423,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,140 +17 2932 . G <*> 0 . DP=4;I16=2,2,0,0,127,4237,0,0,240,14400,0,0,65,1447,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,117 +17 2933 . G <*> 0 . DP=4;I16=2,2,0,0,126,4124,0,0,240,14400,0,0,65,1475,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,116 +17 2934 . C <*> 0 . DP=3;I16=2,1,0,0,110,4052,0,0,180,10800,0,0,66,1506,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,104 +17 2935 . C <*> 0 . DP=3;I16=2,1,0,0,99,3353,0,0,180,10800,0,0,67,1539,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,94 +17 2936 . T <*> 0 . DP=3;I16=2,1,0,0,104,3654,0,0,180,10800,0,0,68,1574,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,98 +17 2937 . G <*> 0 . DP=3;I16=2,1,0,0,84,2574,0,0,180,10800,0,0,69,1611,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,79 +17 2938 . T <*> 0 . DP=3;I16=2,1,0,0,107,3865,0,0,180,10800,0,0,70,1650,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,101 +17 2939 . C <*> 0 . DP=3;I16=2,1,0,0,112,4210,0,0,180,10800,0,0,71,1691,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,106 +17 2940 . T <*> 0 . DP=3;I16=2,1,0,0,116,4534,0,0,180,10800,0,0,72,1734,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,109 +17 2941 . T <*> 0 . DP=3;I16=2,1,0,0,104,3650,0,0,180,10800,0,0,73,1779,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,99 +17 2942 . T <*> 0 . DP=3;I16=2,1,0,0,106,3780,0,0,180,10800,0,0,74,1826,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,100 +17 2943 . G <*> 0 . DP=3;I16=2,1,0,0,91,2861,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,86 +17 2944 . A <*> 0 . DP=3;I16=2,1,0,0,118,4646,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,111 +17 2945 . A <*> 0 . DP=3;I16=2,1,0,0,113,4277,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,107 +17 2946 . A <*> 0 . DP=3;I16=2,1,0,0,114,4334,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,108 +17 2947 . G <*> 0 . DP=3;I16=2,1,0,0,82,2302,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,78 +17 2948 . G <*> 0 . DP=4;I16=2,2,0,0,127,4081,0,0,240,14400,0,0,75,1875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,116 +17 2949 . C <*> 0 . DP=4;I16=2,2,0,0,135,4697,0,0,240,14400,0,0,76,1876,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,124 +17 2950 . C <*> 0 . DP=4;I16=2,2,0,0,124,4138,0,0,240,14400,0,0,77,1879,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,115 +17 2951 . A <*> 0 . DP=4;I16=2,2,0,0,146,5346,0,0,240,14400,0,0,78,1884,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,133 +17 2952 . C <*> 0 . DP=4;I16=2,2,0,0,122,3860,0,0,240,14400,0,0,79,1891,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,112 +17 2953 . G <*> 0 . DP=4;I16=2,2,0,0,121,3765,0,0,240,14400,0,0,80,1900,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,111 +17 2954 . T <*> 0 . DP=4;I16=2,2,0,0,148,5584,0,0,240,14400,0,0,80,1862,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,135 +17 2955 . G <*> 0 . DP=4;I16=2,2,0,0,138,4830,0,0,240,14400,0,0,80,1828,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,127 +17 2956 . A <*> 0 . DP=4;I16=2,2,0,0,137,4833,0,0,240,14400,0,0,80,1798,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,125 +17 2957 . C <*> 0 . DP=4;I16=2,1,0,0,110,4058,0,0,180,10800,0,0,55,1147,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,104 +17 2958 . C <*> 0 . DP=4;I16=2,2,0,0,148,5506,0,0,240,14400,0,0,80,1750,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,135 +17 2959 . T <*> 0 . DP=4;I16=2,2,0,0,152,5852,0,0,240,14400,0,0,80,1732,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,139 +17 2960 . G <*> 0 . DP=4;I16=2,2,0,0,136,4890,0,0,240,14400,0,0,80,1718,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,126 +17 2961 . G <*> 0 . DP=4;I16=2,1,0,0,117,4577,0,0,180,10800,0,0,55,1083,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,111 +17 2962 . C <*> 0 . DP=4;I16=2,2,0,0,144,5288,0,0,240,14400,0,0,78,1606,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,132 +17 2963 . C <*> 0 . DP=4;I16=2,1,0,0,106,3774,0,0,180,10800,0,0,55,1075,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,100 +17 2964 . C <*> 0 . DP=5;I16=3,2,0,0,173,6043,0,0,300,18000,0,0,76,1518,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,151 +17 2965 . A <*> 0 . DP=5;I16=3,2,0,0,178,6448,0,0,300,18000,0,0,76,1484,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,155 +17 2966 . C <*> 0 . DP=5;I16=3,2,0,0,163,5467,0,0,300,18000,0,0,76,1458,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,142 +17 2967 . G <*> 0 . DP=6;I16=3,3,0,0,160,4500,0,0,360,21600,0,0,76,1440,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,135 +17 2968 . G <*> 0 . DP=6;I16=3,3,0,0,191,6355,0,0,360,21600,0,0,77,1431,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,162 +17 2969 . C <*> 0 . DP=6;I16=3,3,0,0,217,7875,0,0,360,21600,0,0,78,1432,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,181 +17 2970 . T <*> 0 . DP=6;I16=3,3,0,0,227,8599,0,0,360,21600,0,0,79,1443,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,189 +17 2971 . G <*> 0 . DP=6;I16=3,3,0,0,220,8082,0,0,360,21600,0,0,80,1464,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,184 +17 2972 . G <*> 0 . DP=6;I16=3,3,0,0,193,6229,0,0,360,21600,0,0,81,1495,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,161 +17 2973 . C <*> 0 . DP=6;I16=3,3,0,0,198,6572,0,0,360,21600,0,0,82,1536,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,165 +17 2974 . A <*> 0 . DP=6;I16=3,3,0,0,208,7252,0,0,360,21600,0,0,82,1536,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,174 +17 2975 . G <*> 0 . DP=6;I16=3,3,0,0,197,6675,0,0,360,21600,0,0,82,1544,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,167 +17 2976 . G <*> 0 . DP=6;I16=3,3,0,0,202,6958,0,0,360,21600,0,0,82,1560,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,171 +17 2977 . T <*> 0 . DP=6;I16=3,3,0,0,183,5889,0,0,360,21600,0,0,82,1584,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,155 +17 2978 . G <*> 0 . DP=6;I16=3,3,0,0,197,6703,0,0,360,21600,0,0,82,1616,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,167 +17 2979 . G <*> 0 . DP=5;I16=2,3,0,0,162,5406,0,0,300,18000,0,0,83,1655,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,142 +17 2980 . G <*> 0 . DP=5;I16=2,3,0,0,168,5842,0,0,300,18000,0,0,84,1700,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,148 +17 2981 . A <*> 0 . DP=5;I16=2,3,0,0,173,6031,0,0,300,18000,0,0,85,1751,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,150 +17 2982 . C <*> 0 . DP=5;I16=2,3,0,0,166,5634,0,0,300,18000,0,0,86,1808,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,144 +17 2983 . C <*> 0 . DP=5;I16=2,3,0,0,161,5459,0,0,300,18000,0,0,87,1871,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,142 +17 2984 . C <*> 0 . DP=5;I16=2,3,0,0,179,6549,0,0,300,18000,0,0,88,1940,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,157 +17 2985 . A <*> 0 . DP=5;I16=2,3,0,0,173,6069,0,0,300,18000,0,0,89,2015,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,151 +17 2986 . G <*> 0 . DP=4;I16=2,2,0,0,137,4835,0,0,240,14400,0,0,91,2095,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,126 +17 2987 . C <*> 0 . DP=4;I16=2,2,0,0,145,5263,0,0,240,14400,0,0,93,2179,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,132 +17 2988 . T <*> 0 . DP=4;I16=2,2,0,0,148,5586,0,0,240,14400,0,0,95,2267,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,136 +17 2989 . G <*> 0 . DP=4;I16=2,2,0,0,136,4764,0,0,240,14400,0,0,97,2359,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,125 +17 2990 . C <*> 0 . DP=4;I16=2,2,0,0,140,4970,0,0,240,14400,0,0,98,2404,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,129 +17 2991 . A <*> 0 . DP=4;I16=2,2,0,0,143,5197,0,0,240,14400,0,0,99,2451,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,131 +17 2992 . G <*> 0 . DP=4;I16=2,2,0,0,131,4581,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,120 +17 2993 . G <*> 0 . DP=4;I16=2,2,0,0,134,4698,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,123 +17 2994 . G <*> 0 . DP=4;I16=2,2,0,0,127,4217,0,0,240,14400,0,0,99,2451,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,116 +17 2995 . G <*> 0 . DP=4;I16=2,2,0,0,147,5451,0,0,240,14400,0,0,98,2404,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,135 +17 2996 . T <*> 0 . DP=4;I16=1,2,0,0,114,4428,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,107 +17 2997 . C <*> 0 . DP=4;I16=2,2,0,0,125,4001,0,0,240,14400,0,0,96,2316,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,115 +17 2998 . C <*> 0 . DP=4;I16=2,2,0,0,134,4610,0,0,240,14400,0,0,95,2275,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,123 +17 2999 . A <*> 0 . DP=4;I16=2,2,0,0,148,5574,0,0,240,14400,0,0,94,2236,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,136 +17 3000 . G <*> 0 . DP=4;I16=2,2,0,0,147,5495,0,0,240,14400,0,0,93,2199,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,135 +17 3001 . C <*> 0 . DP=4;I16=2,2,0,0,139,4971,0,0,240,14400,0,0,92,2164,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,128 +17 3002 . A <*> 0 . DP=4;I16=2,2,0,0,151,5779,0,0,240,14400,0,0,91,2131,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,139 +17 3003 . G <*> 0 . DP=4;I16=2,2,0,0,131,4365,0,0,240,14400,0,0,90,2100,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,120 +17 3004 . C <*> 0 . DP=4;I16=2,2,0,0,141,5039,0,0,240,14400,0,0,89,2071,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,129 +17 3005 . A <*> 0 . DP=4;I16=2,2,0,0,136,4674,0,0,240,14400,0,0,88,2044,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,124 +17 3006 . C <*> 0 . DP=4;I16=2,2,0,0,148,5496,0,0,240,14400,0,0,87,2019,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,135 +17 3007 . C <*> 0 . DP=4;I16=2,2,0,0,157,6187,0,0,240,14400,0,0,86,1996,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,144 +17 3008 . C <*> 0 . DP=4;I16=2,2,0,0,158,6270,0,0,240,14400,0,0,85,1975,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,145 +17 3009 . A <*> 0 . DP=4;I16=2,2,0,0,142,5116,0,0,240,14400,0,0,84,1956,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,130 +17 3010 . C <*> 0 . DP=4;I16=2,2,0,0,147,5445,0,0,240,14400,0,0,83,1939,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,135 +17 3011 . A <*> 0 . DP=4;I16=2,2,0,0,158,6254,0,0,240,14400,0,0,82,1924,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,145 +17 3012 . G <*> 0 . DP=4;I16=2,2,0,0,155,6017,0,0,240,14400,0,0,81,1911,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,141 +17 3013 . C <*> 0 . DP=4;I16=2,2,0,0,154,5946,0,0,240,14400,0,0,80,1900,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,141 +17 3014 . A <*> 0 . DP=4;I16=2,2,0,0,154,5988,0,0,240,14400,0,0,79,1891,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,141 +17 3015 . G <*> 0 . DP=4;I16=2,2,0,0,143,5143,0,0,240,14400,0,0,78,1884,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,131 +17 3016 . C <*> 0 . DP=4;I16=2,2,0,0,144,5214,0,0,240,14400,0,0,77,1879,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,132 +17 3017 . C <*> 0 . DP=4;I16=2,2,0,0,140,4952,0,0,240,14400,0,0,76,1876,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,128 +17 3018 . A <*> 0 . DP=4;I16=1,2,0,0,86,2486,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,81 +17 3019 . C <*> 0 . DP=3;I16=1,2,0,0,110,4052,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,104 +17 3020 . C <*> 0 . DP=3;I16=1,2,0,0,121,4889,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,114 +17 3021 . T <*> 0 . DP=3;I16=1,2,0,0,116,4506,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,109 +17 3022 . G <*> 0 . DP=3;I16=1,2,0,0,116,4506,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,109 +17 3023 . T <*> 0 . DP=3;I16=1,2,0,0,117,4571,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,111 +17 3024 . G <*> 0 . DP=3;I16=1,2,0,0,120,4814,0,0,180,10800,0,0,74,1826,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,113 +17 3025 . G <*> 0 . DP=3;I16=1,2,0,0,116,4554,0,0,180,10800,0,0,73,1779,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,109 +17 3026 . C <*> 0 . DP=3;I16=1,2,0,0,114,4346,0,0,180,10800,0,0,72,1734,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,107 +17 3027 . A <*> 0 . DP=3;I16=1,2,0,0,115,4469,0,0,180,10800,0,0,71,1691,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,108 +17 3028 . G <*> 0 . DP=3;I16=1,2,0,0,114,4430,0,0,180,10800,0,0,70,1650,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,107 +17 3029 . G <*> 0 . DP=3;I16=1,2,0,0,115,4441,0,0,180,10800,0,0,69,1611,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,109 +17 3030 . G <*> 0 . DP=3;I16=1,2,0,0,112,4202,0,0,180,10800,0,0,68,1574,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,106 +17 3031 . A <*> 0 . DP=3;I16=1,2,0,0,120,4826,0,0,180,10800,0,0,67,1539,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,113 +17 3032 . G <*> 0 . DP=3;I16=1,2,0,0,113,4325,0,0,180,10800,0,0,66,1506,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,106 +17 3033 . G <*> 0 . DP=3;I16=1,2,0,0,113,4285,0,0,180,10800,0,0,65,1475,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,106 +17 3034 . A <*> 0 . DP=4;I16=2,2,0,0,137,4921,0,0,240,14400,0,0,64,1446,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,126 +17 3035 . G <*> 0 . DP=4;I16=2,2,0,0,140,5006,0,0,240,14400,0,0,64,1420,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,128 +17 3036 . C <*> 0 . DP=4;I16=2,2,0,0,153,5879,0,0,240,14400,0,0,64,1398,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,140 +17 3037 . T <*> 0 . DP=4;I16=2,2,0,0,156,6110,0,0,240,14400,0,0,64,1380,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,143 +17 3038 . T <*> 0 . DP=4;I16=2,2,0,0,137,4711,0,0,240,14400,0,0,64,1366,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,125 +17 3039 . G <*> 0 . DP=4;I16=2,2,0,0,139,4887,0,0,240,14400,0,0,64,1356,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,127 +17 3040 . T <*> 0 . DP=4;I16=2,2,0,0,142,5102,0,0,240,14400,0,0,63,1301,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,130 +17 3041 . G <*> 0 . DP=4;I16=2,2,0,0,147,5435,0,0,240,14400,0,0,62,1252,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,135 +17 3042 . G <*> 0 . DP=4;I16=2,2,0,0,131,4313,0,0,240,14400,0,0,61,1209,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,120 +17 3043 . T <*> 0 . DP=4;I16=2,2,0,0,135,4779,0,0,240,14400,0,0,59,1123,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,124 +17 3044 . A <*> 0 . DP=4;I16=2,2,0,0,136,4668,0,0,240,14400,0,0,57,1045,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,124 +17 3045 . C <*> 0 . DP=4;I16=2,2,0,0,132,4622,0,0,240,14400,0,0,55,975,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,122 +17 3046 . A <*> 0 . DP=4;I16=2,2,0,0,154,5974,0,0,240,14400,0,0,53,913,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,141 +17 3047 . G <*> 0 . DP=4;I16=2,2,0,0,141,5003,0,0,240,14400,0,0,51,859,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,129 +17 3048 . T <*> 0 . DP=4;I16=2,2,0,0,141,5019,0,0,240,14400,0,0,49,813,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,129 +17 3049 . G <*> 0 . DP=3;I16=2,1,0,0,111,4109,0,0,180,10800,0,0,48,774,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,105 +17 3050 . G <*> 0 . DP=3;I16=2,1,0,0,106,3770,0,0,180,10800,0,0,47,741,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,100 +17 3051 . A <*> 0 . DP=3;I16=2,1,0,0,109,3989,0,0,180,10800,0,0,46,714,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,103 +17 3052 . C <*> 0 . DP=3;I16=2,1,0,0,97,3331,0,0,180,10800,0,0,45,693,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,93 +17 3053 . A <*> 0 . DP=3;I16=2,1,0,0,117,4577,0,0,180,10800,0,0,44,678,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,110 +17 3054 . G <*> 0 . DP=3;I16=2,1,0,0,103,3811,0,0,180,10800,0,0,43,669,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,99 +17 3055 . G <*> 0 . DP=4;I16=2,1,0,0,111,4169,0,0,180,10800,0,0,42,666,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,105 +17 3056 . C <*> 0 . DP=4;I16=2,2,0,0,132,4642,0,0,240,14400,0,0,66,1294,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,122 +17 3057 . C <*> 0 . DP=4;I16=1,2,0,0,96,3338,0,0,180,10800,0,0,58,1254,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,92 +17 3058 . C <*> 0 . DP=4;I16=2,2,0,0,125,4207,0,0,240,14400,0,0,64,1318,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,116 +17 3059 . T <*> 0 . DP=4;I16=2,1,0,0,97,3561,0,0,180,10800,0,0,38,714,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,94 +17 3060 . G <*> 0 . DP=5;I16=2,2,0,0,126,4164,0,0,240,14400,0,0,61,1315,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,116 +17 3061 . C <*> 0 . DP=5;I16=2,3,0,0,167,5659,0,0,300,18000,0,0,84,1920,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,145 +17 3062 . C <*> 0 . DP=5;I16=2,3,0,0,153,4913,0,0,300,18000,0,0,82,1904,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,134 +17 3063 . C <*> 0 . DP=5;I16=2,3,0,0,149,4995,0,0,300,18000,0,0,80,1892,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,133 +17 3064 . A <*> 0 . DP=5;I16=2,3,0,0,164,5622,0,0,300,18000,0,0,78,1884,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,144 +17 3065 . G <*> 0 . DP=4;I16=1,3,0,0,132,4526,0,0,240,14400,0,0,77,1879,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,118 +17 3066 . A <*> 0 . DP=4;I16=1,3,0,0,115,3749,0,0,240,14400,0,0,76,1876,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,104 +17 3067 . T <*> 0 . DP=4;I16=1,3,0,0,114,3570,0,0,240,14400,0,0,75,1875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,103 +17 3068 . G <*> 0 . DP=3;I16=1,2,0,0,88,2790,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,84 +17 3069 . G <*> 0 . DP=3;I16=1,1,0,0,57,1889,0,0,120,7200,0,0,50,1250,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,6,57 +17 3070 . C <*> 0 . DP=3;I16=1,2,0,0,103,3649,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,98 +17 3071 . C <*> 0 . DP=3;I16=1,2,0,0,104,3656,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,98 +17 3072 . C <*> 0 . DP=3;I16=1,2,0,0,112,4230,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,106 +17 3073 . C <*> 0 . DP=3;I16=1,2,0,0,122,4986,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,115 +17 3074 . C <*> 0 . DP=3;I16=1,2,0,0,123,5057,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,116 +17 3075 . C <*> 0 . DP=3;I16=1,2,0,0,99,3461,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,94 +17 3076 . G <*> 0 . DP=3;I16=1,2,0,0,96,3098,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,91 +17 3077 . C <*> 0 . DP=3;I16=1,2,0,0,117,4619,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,111 +17 3078 . C <*> 0 . DP=3;I16=1,2,0,0,117,4605,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,111 +17 3079 . T <*> 0 . DP=3;I16=1,2,0,0,123,5061,0,0,180,10800,0,0,74,1826,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,116 +17 3080 . G <*> 0 . DP=3;I16=1,2,0,0,109,4021,0,0,180,10800,0,0,73,1779,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,103 +17 3081 . C <*> 0 . DP=3;I16=1,2,0,0,97,3221,0,0,180,10800,0,0,72,1734,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,92 +17 3082 . C <*> 0 . DP=3;I16=1,2,0,0,119,4721,0,0,180,10800,0,0,71,1691,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,112 +17 3083 . T <*> 0 . DP=3;I16=1,2,0,0,120,4824,0,0,180,10800,0,0,70,1650,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,113 +17 3084 . G <*> 0 . DP=4;I16=1,3,0,0,153,5887,0,0,240,14400,0,0,69,1611,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,135 +17 3085 . T <*> 0 . DP=4;I16=1,3,0,0,153,5857,0,0,240,14400,0,0,69,1575,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,135 +17 3086 . G <*> 0 . DP=4;I16=1,3,0,0,149,5569,0,0,240,14400,0,0,69,1543,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,131 +17 3087 . G <*> 0 . DP=4;I16=1,3,0,0,155,6031,0,0,240,14400,0,0,69,1515,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,137 +17 3088 . A <*> 0 . DP=4;I16=1,3,0,0,154,5956,0,0,240,14400,0,0,69,1491,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,135 +17 3089 . A <*> 0 . DP=5;I16=2,3,0,0,202,8232,0,0,300,18000,0,0,69,1471,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,175 +17 3090 . G <*> 0 . DP=5;I16=2,3,0,0,185,6855,0,0,300,18000,0,0,70,1456,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,160 +17 3091 . T <*> 0 . DP=5;I16=2,3,0,0,174,6552,0,0,300,18000,0,0,71,1447,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,153 +17 3092 . T <*> 0 . DP=5;I16=2,3,0,0,189,7193,0,0,300,18000,0,0,72,1444,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,165 +17 3093 . G <*> 0 . DP=5;I16=2,3,0,0,179,6575,0,0,300,18000,0,0,73,1447,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,157 +17 3094 . A <*> 0 . DP=5;I16=2,3,0,0,185,6961,0,0,300,18000,0,0,74,1456,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,161 +17 3095 . C <*> 0 . DP=5;I16=2,3,0,0,188,7122,0,0,300,18000,0,0,75,1471,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,163 +17 3096 . C <*> 0 . DP=5;I16=2,3,0,0,193,7465,0,0,300,18000,0,0,76,1492,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,167 +17 3097 . A <*> 0 . DP=5;I16=2,3,0,0,200,8034,0,0,300,18000,0,0,77,1519,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,174 +17 3098 . G <*> 0 . DP=5;I16=2,3,0,0,191,7333,0,0,300,18000,0,0,78,1552,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,166 +17 3099 . A <*> 0 . DP=5;I16=2,3,0,0,191,7299,0,0,300,18000,0,0,78,1542,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,165 +17 3100 . C <*> 0 . DP=5;I16=2,3,0,0,184,6802,0,0,300,18000,0,0,78,1540,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,159 +17 3101 . C <*> 0 . DP=5;I16=2,3,0,0,186,6930,0,0,300,18000,0,0,78,1546,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,161 +17 3102 . A <*> 0 . DP=6;I16=3,3,0,0,226,8548,0,0,360,21600,0,0,78,1560,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,189 +17 3103 . T <*> 0 . DP=6;I16=3,3,0,0,223,8347,0,0,360,21600,0,0,79,1583,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,187 +17 3104 . C T,<*> 0 . DP=5;I16=1,2,2,0,114,4334,80,3202,180,10800,120,7200,41,765,40,850;QS=0.587629,0.412371,0;VDB=0.8;SGB=-0.453602;RPB=0.833333;MQB=1;MQSB=1;BQB=0.166667;MQ0F=0 PL 59,0,93,68,99,157 +17 3105 . T <*> 0 . DP=5;I16=3,2,0,0,195,7621,0,0,300,18000,0,0,83,1655,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,169 +17 3106 . G <*> 0 . DP=5;I16=3,2,0,0,193,7461,0,0,300,18000,0,0,85,1703,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,167 +17 3107 . T <*> 0 . DP=6;I16=3,3,0,0,233,9067,0,0,360,21600,0,0,87,1759,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,195 +17 3108 . C <*> 0 . DP=6;I16=3,3,0,0,226,8562,0,0,360,21600,0,0,90,1824,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,189 +17 3109 . A <*> 0 . DP=6;I16=3,3,0,0,234,9146,0,0,360,21600,0,0,93,1899,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,195 +17 3110 . C <*> 0 . DP=6;I16=3,3,0,0,226,8534,0,0,360,21600,0,0,94,1884,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,189 +17 3111 . A <*> 0 . DP=6;I16=3,3,0,0,244,10014,0,0,360,21600,0,0,95,1879,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,205 +17 3112 . G <*> 0 . DP=6;I16=3,3,0,0,227,8745,0,0,360,21600,0,0,96,1884,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,191 +17 3113 . C <*> 0 . DP=6;I16=3,3,0,0,231,8947,0,0,360,21600,0,0,97,1899,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,193 +17 3114 . A <*> 0 . DP=6;I16=3,3,0,0,239,9559,0,0,360,21600,0,0,98,1924,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,200 +17 3115 . G <*> 0 . DP=6;I16=3,3,0,0,233,9095,0,0,360,21600,0,0,98,1908,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,195 +17 3116 . G <*> 0 . DP=6;I16=3,3,0,0,232,9014,0,0,360,21600,0,0,98,1900,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,194 +17 3117 . T <*> 0 . DP=6;I16=3,3,0,0,209,7553,0,0,360,21600,0,0,98,1900,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,177 +17 3118 . A <*> 0 . DP=6;I16=3,3,0,0,231,8907,0,0,360,21600,0,0,98,1908,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,193 +17 3119 . A <*> 0 . DP=6;I16=3,3,0,0,248,10278,0,0,360,21600,0,0,98,1924,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,207 +17 3120 . G <*> 0 . DP=6;I16=3,3,0,0,217,7947,0,0,360,21600,0,0,98,1948,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,182 +17 3121 . A <*> 0 . DP=6;I16=3,3,0,0,232,9014,0,0,360,21600,0,0,98,1980,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,194 +17 3122 . C <*> 0 . DP=6;I16=3,3,0,0,229,8779,0,0,360,21600,0,0,98,2020,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,192 +17 3123 . T <*> 0 . DP=6;I16=3,3,0,0,242,9864,0,0,360,21600,0,0,98,2068,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,204 +17 3124 . C <*> 0 . DP=5;I16=3,2,0,0,206,8500,0,0,300,18000,0,0,99,2123,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,178 +17 3125 . T <*> 0 . DP=5;I16=3,2,0,0,213,9081,0,0,300,18000,0,0,100,2184,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,185 +17 3126 . G <*> 0 . DP=5;I16=3,2,0,0,201,8093,0,0,300,18000,0,0,101,2251,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,174 +17 3127 . C <*> 0 . DP=5;I16=3,2,0,0,202,8174,0,0,300,18000,0,0,102,2324,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,175 +17 3128 . T <*> 0 . DP=5;I16=3,2,0,0,209,8753,0,0,300,18000,0,0,102,2352,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,182 +17 3129 . T <*> 0 . DP=5;I16=3,2,0,0,206,8506,0,0,300,18000,0,0,102,2384,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,178 +17 3130 . T <*> 0 . DP=5;I16=3,2,0,0,195,7663,0,0,300,18000,0,0,102,2420,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,169 +17 3131 . C <*> 0 . DP=5;I16=3,2,0,0,196,7724,0,0,300,18000,0,0,102,2460,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,170 +17 3132 . T <*> 0 . DP=5;I16=3,2,0,0,200,8048,0,0,300,18000,0,0,102,2504,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,174 +17 3133 . G <*> 0 . DP=5;I16=3,2,0,0,191,7405,0,0,300,18000,0,0,101,2501,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,166 +17 3134 . G <*> 0 . DP=5;I16=3,2,0,0,185,7049,0,0,300,18000,0,0,100,2500,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,163 +17 3135 . G <*> 0 . DP=4;I16=2,2,0,0,165,6819,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,151 +17 3136 . C <*> 0 . DP=4;I16=2,2,0,0,153,5945,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,140 +17 3137 . A <*> 0 . DP=4;I16=2,2,0,0,155,6037,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,142 +17 3138 . A <*> 0 . DP=4;I16=2,2,0,0,161,6523,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,147 +17 3139 . C <*> 0 . DP=4;I16=2,2,0,0,152,5790,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,139 +17 3140 . C <*> 0 . DP=4;I16=2,2,0,0,159,6365,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,145 +17 3141 . C <*> 0 . DP=4;I16=2,2,0,0,163,6705,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,150 +17 3142 . A <*> 0 . DP=4;I16=2,2,0,0,169,7149,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,155 +17 3143 . G <*> 0 . DP=4;I16=2,2,0,0,165,6825,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,151 +17 3144 . C <*> 0 . DP=5;I16=3,2,0,0,190,7296,0,0,300,18000,0,0,100,2500,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,165 +17 3145 . A <*> 0 . DP=5;I16=3,2,0,0,200,8046,0,0,300,18000,0,0,101,2501,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,174 +17 3146 . G <*> 0 . DP=5;I16=3,2,0,0,206,8530,0,0,300,18000,0,0,102,2504,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,179 +17 3147 . G <*> 0 . DP=5;I16=3,2,0,0,198,7910,0,0,300,18000,0,0,103,2509,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,172 +17 3148 . T <*> 0 . DP=5;I16=3,2,0,0,169,5971,0,0,300,18000,0,0,104,2516,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,149 +17 3149 . G <*> 0 . DP=5;I16=3,2,0,0,192,7406,0,0,300,18000,0,0,105,2525,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,167 +17 3150 . A <*> 0 . DP=5;I16=3,2,0,0,190,7414,0,0,300,18000,0,0,106,2536,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,167 +17 3151 . C <*> 0 . DP=5;I16=3,2,0,0,188,7090,0,0,300,18000,0,0,107,2549,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,163 +17 3152 . C <*> 0 . DP=5;I16=3,2,0,0,177,6411,0,0,300,18000,0,0,108,2564,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,155 +17 3153 . C <*> 0 . DP=5;I16=3,2,0,0,190,7326,0,0,300,18000,0,0,109,2581,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,166 +17 3154 . T <*> 0 . DP=6;I16=4,2,0,0,235,9351,0,0,360,21600,0,0,110,2600,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,194 +17 3155 . G <*> 0 . DP=6;I16=4,2,0,0,220,8160,0,0,360,21600,0,0,112,2622,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,180 +17 3156 . G <*> 0 . DP=6;I16=4,2,0,0,230,8940,0,0,360,21600,0,0,114,2648,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,189 +17 3157 . A <*> 0 . DP=6;I16=4,2,0,0,235,9261,0,0,360,21600,0,0,116,2678,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,193 +17 3158 . A <*> 0 . DP=6;I16=4,2,0,0,235,9263,0,0,360,21600,0,0,118,2712,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,192 +17 3159 . T <*> 0 . DP=6;I16=4,2,0,0,236,9366,0,0,360,21600,0,0,120,2750,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,194 +17 3160 . T <*> 0 . DP=6;I16=4,2,0,0,233,9325,0,0,360,21600,0,0,121,2743,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,193 +17 3161 . C <*> 0 . DP=6;I16=4,2,0,0,239,9617,0,0,360,21600,0,0,122,2742,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,196 +17 3162 . C <*> 0 . DP=6;I16=4,2,0,0,227,8857,0,0,360,21600,0,0,123,2747,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,188 +17 3163 . T <*> 0 . DP=6;I16=4,2,0,0,242,9898,0,0,360,21600,0,0,124,2758,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,200 +17 3164 . G <*> 0 . DP=6;I16=4,2,0,0,229,8893,0,0,360,21600,0,0,125,2775,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,188 +17 3165 . T <*> 0 . DP=6;I16=4,2,0,0,232,9004,0,0,360,21600,0,0,125,2749,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,189 +17 3166 . C <*> 0 . DP=6;I16=4,2,0,0,238,9460,0,0,360,21600,0,0,125,2731,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,193 +17 3167 . C <*> 0 . DP=6;I16=4,2,0,0,230,8932,0,0,360,21600,0,0,125,2721,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,189 +17 3168 . A <*> 0 . DP=6;I16=4,2,0,0,236,9292,0,0,360,21600,0,0,125,2719,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,192 +17 3169 . T <*> 0 . DP=6;I16=4,2,0,0,229,8803,0,0,360,21600,0,0,125,2725,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,187 +17 3170 . C <*> 0 . DP=6;I16=4,2,0,0,246,10098,0,0,360,21600,0,0,124,2688,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,201 +17 3171 . T <*> 0 . DP=6;I16=4,2,0,0,245,10039,0,0,360,21600,0,0,123,2657,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,201 +17 3172 . G <*> 0 . DP=6;I16=4,2,0,0,213,7757,0,0,360,21600,0,0,122,2632,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,176 +17 3173 . G <*> 0 . DP=6;I16=4,2,0,0,211,7615,0,0,360,21600,0,0,121,2613,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,174 +17 3174 . C <*> 0 . DP=6;I16=4,2,0,0,237,9423,0,0,360,21600,0,0,120,2600,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,194 +17 3175 . A <*> 0 . DP=7;I16=5,2,0,0,271,10615,0,0,420,25200,0,0,119,2593,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,209 +17 3176 . G <*> 0 . DP=7;I16=5,2,0,0,268,10330,0,0,420,25200,0,0,119,2593,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,205 +17 3177 . G <*> 0 . DP=7;I16=5,2,0,0,252,9250,0,0,420,25200,0,0,119,2601,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,195 +17 3178 . T <*> 0 . DP=7;I16=5,2,0,0,222,7256,0,0,420,25200,0,0,118,2568,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,173 +17 3179 . G <*> 0 . DP=7;I16=5,2,0,0,243,8581,0,0,420,25200,0,0,117,2545,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,188 +17 3180 . G <*> 0 . DP=7;I16=5,2,0,0,225,7415,0,0,420,25200,0,0,115,2481,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,175 +17 3181 . G <*> 0 . DP=7;I16=5,2,0,0,252,9126,0,0,420,25200,0,0,113,2425,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,193 +17 3182 . C <*> 0 . DP=7;I16=5,2,0,0,239,8287,0,0,420,25200,0,0,111,2377,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,184 +17 3183 . A <*> 0 . DP=7;I16=5,2,0,0,248,8966,0,0,420,25200,0,0,108,2288,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,193 +17 3184 . T <*> 0 . DP=7;I16=5,2,0,0,252,9234,0,0,420,25200,0,0,105,2209,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,196 +17 3185 . T <*> 0 . DP=6;I16=5,1,0,0,231,8911,0,0,360,21600,0,0,103,2139,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,174 +17 3186 . G <*> 0 . DP=6;I16=5,1,0,0,221,8275,0,0,360,21600,0,0,101,2077,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,169 +17 3187 . A <*> 0 . DP=6;I16=5,1,0,0,224,8458,0,0,360,21600,0,0,99,2023,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,171 +17 3188 . A <*> 0 . DP=6;I16=5,1,0,0,231,8933,0,0,360,21600,0,0,97,1977,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,174 +17 3189 . A <*> 0 . DP=6;I16=5,1,0,0,229,8829,0,0,360,21600,0,0,95,1939,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,174 +17 3190 . C <*> 0 . DP=5;I16=4,1,0,0,182,6662,0,0,300,18000,0,0,94,1908,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,148 +17 3191 . T <*> 0 . DP=5;I16=4,1,0,0,209,8749,0,0,300,18000,0,0,93,1883,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,171 +17 3192 . G <*> 0 . DP=5;I16=4,1,0,0,186,6978,0,0,300,18000,0,0,92,1864,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,152 +17 3193 . G <*> 0 . DP=5;I16=4,1,0,0,181,6633,0,0,300,18000,0,0,91,1851,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,148 +17 3194 . T <*> 0 . DP=6;I16=4,2,0,0,216,7882,0,0,360,21600,0,0,90,1844,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,178 +17 3195 . T <*> 0 . DP=6;I16=4,2,0,0,231,8971,0,0,360,21600,0,0,90,1844,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,189 +17 3196 . T <*> 0 . DP=6;I16=4,2,0,0,228,8738,0,0,360,21600,0,0,90,1852,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,186 +17 3197 . A <*> 0 . DP=6;I16=4,2,0,0,219,8029,0,0,360,21600,0,0,90,1868,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,179 +17 3198 . A <*> 0 . DP=6;I16=4,2,0,0,243,9855,0,0,360,21600,0,0,90,1892,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,198 +17 3199 . A <*> 0 . DP=6;I16=4,2,0,0,240,9620,0,0,360,21600,0,0,90,1924,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,196 +17 3200 . A <*> 0 . DP=6;I16=4,2,0,0,238,9490,0,0,360,21600,0,0,90,1964,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,195 +17 3201 . A <*> 0 . DP=6;I16=4,2,0,0,242,9796,0,0,360,21600,0,0,89,1961,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,198 +17 3202 . T <*> 0 . DP=6;I16=4,2,0,0,227,8733,0,0,360,21600,0,0,88,1964,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,187 +17 3203 . G <*> 0 . DP=5;I16=3,2,0,0,185,6875,0,0,300,18000,0,0,88,1972,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,160 +17 3204 . T <*> 0 . DP=5;I16=3,2,0,0,195,7631,0,0,300,18000,0,0,88,1984,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,169 +17 3205 . C <*> 0 . DP=5;I16=3,2,0,0,181,6571,0,0,300,18000,0,0,88,2000,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,157 +17 3206 . A <*> 0 . DP=5;I16=3,2,0,0,191,7317,0,0,300,18000,0,0,88,2020,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,165 +17 3207 . C <*> 0 . DP=5;I16=3,2,0,0,182,6686,0,0,300,18000,0,0,88,2044,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,158 +17 3208 . A <*> 0 . DP=4;I16=3,1,0,0,162,6570,0,0,240,14400,0,0,89,2071,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,142 +17 3209 . C <*> 0 . DP=4;I16=3,1,0,0,153,5879,0,0,240,14400,0,0,90,2100,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,134 +17 3210 . C <*> 0 . DP=4;I16=3,1,0,0,161,6491,0,0,240,14400,0,0,91,2131,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,141 +17 3211 . A <*> 0 . DP=4;I16=3,1,0,0,160,6414,0,0,240,14400,0,0,92,2164,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,140 +17 3212 . T <*> 0 . DP=4;I16=3,1,0,0,163,6643,0,0,240,14400,0,0,93,2199,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,144 +17 3213 . A <*> 0 . DP=4;I16=3,1,0,0,157,6217,0,0,240,14400,0,0,94,2236,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,138 +17 3214 . G <*> 0 . DP=4;I16=3,1,0,0,153,5879,0,0,240,14400,0,0,95,2275,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,134 +17 3215 . G <*> 0 . DP=4;I16=3,1,0,0,144,5382,0,0,240,14400,0,0,96,2316,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,128 +17 3216 . C <*> 0 . DP=4;I16=3,1,0,0,157,6173,0,0,240,14400,0,0,97,2359,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,138 +17 3217 . C <*> 0 . DP=4;I16=3,1,0,0,140,5000,0,0,240,14400,0,0,98,2404,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,123 +17 3218 . G <*> 0 . DP=4;I16=3,1,0,0,127,4149,0,0,240,14400,0,0,99,2451,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,112 +17 3219 . G <*> 0 . DP=4;I16=3,1,0,0,144,5220,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,126 +17 3220 . G <*> 0 . DP=4;I16=3,1,0,0,144,5214,0,0,240,14400,0,0,99,2451,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,126 +17 3221 . C <*> 0 . DP=4;I16=3,1,0,0,159,6323,0,0,240,14400,0,0,98,2404,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,139 +17 3222 . A <*> 0 . DP=4;I16=3,1,0,0,151,5755,0,0,240,14400,0,0,97,2359,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,133 +17 3223 . C <*> 0 . DP=4;I16=3,1,0,0,150,5660,0,0,240,14400,0,0,96,2316,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,132 +17 3224 . A <*> 0 . DP=4;I16=3,1,0,0,161,6489,0,0,240,14400,0,0,95,2275,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,141 +17 3225 . G <*> 0 . DP=4;I16=3,1,0,0,152,5830,0,0,240,14400,0,0,94,2236,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,134 +17 3226 . T <*> 0 . DP=4;I16=3,1,0,0,150,5646,0,0,240,14400,0,0,93,2199,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,131 +17 3227 . G <*> 0 . DP=4;I16=3,1,0,0,143,5151,0,0,240,14400,0,0,92,2164,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,125 +17 3228 . G <*> 0 . DP=4;I16=3,1,0,0,138,4806,0,0,240,14400,0,0,91,2131,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,121 +17 3229 . C <*> 0 . DP=4;I16=3,1,0,0,143,5121,0,0,240,14400,0,0,90,2100,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,126 +17 3230 . T <*> 0 . DP=4;I16=3,1,0,0,159,6333,0,0,240,14400,0,0,88,2022,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,139 +17 3231 . C <*> 0 . DP=4;I16=3,1,0,0,146,5350,0,0,240,14400,0,0,86,1948,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,128 +17 3232 . A <*> 0 . DP=4;I16=3,1,0,0,149,5721,0,0,240,14400,0,0,84,1878,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,132 +17 3233 . C <*> 0 . DP=4;I16=3,1,0,0,126,3986,0,0,240,14400,0,0,82,1812,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,110 +17 3234 . G <*> 0 . DP=4;I16=3,1,0,0,112,3510,0,0,240,14400,0,0,80,1750,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,100 +17 3235 . C <*> 0 . DP=4;I16=3,1,0,0,139,4935,0,0,240,14400,0,0,78,1692,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,123 +17 3236 . C <*> 0 . DP=4;I16=3,1,0,0,153,5897,0,0,240,14400,0,0,76,1638,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,134 +17 3237 . T <*> 0 . DP=4;I16=3,1,0,0,154,6020,0,0,240,14400,0,0,74,1588,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,136 +17 3238 . G <*> 0 . DP=4;I16=3,1,0,0,147,5459,0,0,240,14400,0,0,72,1542,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,129 +17 3239 . T <*> 0 . DP=4;I16=3,1,0,0,148,5546,0,0,240,14400,0,0,70,1500,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,131 +17 3240 . A <*> 0 . DP=4;I16=3,1,0,0,150,5668,0,0,240,14400,0,0,68,1462,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,132 +17 3241 . A <*> 0 . DP=4;I16=3,1,0,0,163,6655,0,0,240,14400,0,0,66,1428,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,143 +17 3242 . T <*> 0 . DP=5;I16=4,1,0,0,185,6943,0,0,300,18000,0,0,64,1398,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,152 +17 3243 . C <*> 0 . DP=5;I16=4,1,0,0,181,6629,0,0,300,18000,0,0,63,1373,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,148 +17 3244 . C <*> 0 . DP=5;I16=4,1,0,0,172,6074,0,0,300,18000,0,0,62,1354,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,142 +17 3245 . C <*> 0 . DP=4;I16=3,1,0,0,150,5636,0,0,240,14400,0,0,62,1340,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,131 +17 3246 . A <*> 0 . DP=4;I16=3,1,0,0,159,6325,0,0,240,14400,0,0,62,1330,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,139 +17 3247 . G <*> 0 . DP=4;I16=3,1,0,0,151,5747,0,0,240,14400,0,0,62,1324,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,133 +17 3248 . C <*> 0 . DP=4;I16=3,1,0,0,151,5703,0,0,240,14400,0,0,62,1322,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,132 +17 3249 . C <*> 0 . DP=4;I16=3,1,0,0,152,5790,0,0,240,14400,0,0,62,1324,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,133 +17 3250 . C <*> 0 . DP=4;I16=3,1,0,0,156,6126,0,0,240,14400,0,0,62,1330,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,137 +17 3251 . T <*> 0 . DP=4;I16=3,1,0,0,152,5880,0,0,240,14400,0,0,61,1291,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,135 +17 3252 . T <*> 0 . DP=4;I16=3,1,0,0,141,5161,0,0,240,14400,0,0,60,1258,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,126 +17 3253 . T <*> 0 . DP=4;I16=3,1,0,0,150,5678,0,0,240,14400,0,0,59,1231,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,132 +17 3254 . G <*> 0 . DP=5;I16=3,2,0,0,176,6362,0,0,300,18000,0,0,58,1210,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,154 +17 3255 . G <*> 0 . DP=4;I16=2,2,0,0,130,4610,0,0,240,14400,0,0,59,1195,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,120 +17 3256 . G <*> 0 . DP=4;I16=2,2,0,0,154,6020,0,0,240,14400,0,0,60,1186,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,142 +17 3257 . A <*> 0 . DP=4;I16=2,2,0,0,157,6219,0,0,240,14400,0,0,61,1183,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,144 +17 3258 . G <*> 0 . DP=4;I16=2,2,0,0,159,6365,0,0,240,14400,0,0,62,1186,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,146 +17 3259 . G <*> 0 . DP=4;I16=2,2,0,0,151,5753,0,0,240,14400,0,0,63,1195,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,139 +17 3260 . C <*> 0 . DP=4;I16=2,2,0,0,145,5295,0,0,240,14400,0,0,64,1210,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,133 +17 3261 . C <*> 0 . DP=4;I16=2,2,0,0,151,5707,0,0,240,14400,0,0,65,1231,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,138 +17 3262 . A <*> 0 . DP=4;I16=2,2,0,0,162,6570,0,0,240,14400,0,0,66,1258,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,148 +17 3263 . G <*> 0 . DP=4;I16=2,2,0,0,160,6442,0,0,240,14400,0,0,67,1291,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,146 +17 3264 . G <*> 0 . DP=4;I16=2,2,0,0,156,6120,0,0,240,14400,0,0,68,1330,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,143 +17 3265 . G <*> 0 . DP=4;I16=2,2,0,0,150,5662,0,0,240,14400,0,0,69,1375,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,137 +17 3266 . T <*> 0 . DP=4;I16=1,2,0,0,120,4802,0,0,180,10800,0,0,61,1345,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,113 +17 3267 . G <*> 0 . DP=4;I16=2,2,0,0,144,5394,0,0,240,14400,0,0,71,1483,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,133 +17 3268 . G <*> 0 . DP=4;I16=2,2,0,0,154,6010,0,0,240,14400,0,0,71,1495,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,142 +17 3269 . G <*> 0 . DP=4;I16=2,2,0,0,149,5625,0,0,240,14400,0,0,71,1511,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,137 +17 3270 . T <*> 0 . DP=5;I16=2,2,0,0,148,5560,0,0,240,14400,0,0,65,1457,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,136 +17 3271 . G <*> 0 . DP=4;I16=2,2,0,0,157,6181,0,0,240,14400,0,0,66,1444,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,143 +17 3272 . G <*> 0 . DP=4;I16=2,2,0,0,153,5881,0,0,240,14400,0,0,67,1437,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,140 +17 3273 . A <*> 0 . DP=4;I16=2,2,0,0,161,6485,0,0,240,14400,0,0,68,1436,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,147 +17 3274 . T <*> 0 . DP=4;I16=2,2,0,0,163,6653,0,0,240,14400,0,0,69,1441,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,149 +17 3275 . C <*> 0 . DP=4;I16=2,2,0,0,152,5808,0,0,240,14400,0,0,70,1452,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,139 +17 3276 . A <*> 0 . DP=4;I16=2,2,0,0,154,5948,0,0,240,14400,0,0,71,1469,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,141 +17 3277 . C <*> 0 . DP=4;I16=2,2,0,0,159,6333,0,0,240,14400,0,0,72,1492,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,146 +17 3278 . T <*> 0 . DP=4;I16=2,2,0,0,167,6993,0,0,240,14400,0,0,73,1521,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,153 +17 3279 . T <*> 0 . DP=4;I16=2,2,0,0,164,6728,0,0,240,14400,0,0,74,1556,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,150 +17 3280 . G <*> 0 . DP=4;I16=2,2,0,0,160,6466,0,0,240,14400,0,0,74,1546,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,146 +17 3281 . A <*> 0 . DP=4;I16=2,2,0,0,172,7410,0,0,240,14400,0,0,74,1540,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,157 +17 3282 . G <*> 0 . DP=4;I16=2,2,0,0,164,6738,0,0,240,14400,0,0,74,1538,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,150 +17 3283 . G <*> 0 . DP=4;I16=2,2,0,0,160,6406,0,0,240,14400,0,0,74,1540,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,146 +17 3284 . T <*> 0 . DP=4;I16=2,2,0,0,160,6420,0,0,240,14400,0,0,74,1546,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,146 +17 3285 . C <*> 0 . DP=4;I16=2,2,0,0,157,6167,0,0,240,14400,0,0,74,1556,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,143 +17 3286 . A <*> 0 . DP=4;I16=2,2,0,0,167,6985,0,0,240,14400,0,0,74,1570,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,153 +17 3287 . G <*> 0 . DP=4;I16=2,2,0,0,164,6750,0,0,240,14400,0,0,74,1588,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,150 +17 3288 . G <*> 0 . DP=5;I16=3,2,0,0,188,7194,0,0,300,18000,0,0,74,1610,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,164 +17 3289 . A <*> 0 . DP=5;I16=3,2,0,0,205,8443,0,0,300,18000,0,0,75,1637,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,178 +17 3290 . G <*> 0 . DP=5;I16=3,2,0,0,193,7487,0,0,300,18000,0,0,76,1670,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,168 +17 3291 . T <*> 0 . DP=5;I16=3,2,0,0,193,7485,0,0,300,18000,0,0,77,1709,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,168 +17 3292 . T <*> 0 . DP=5;I16=3,2,0,0,189,7171,0,0,300,18000,0,0,78,1754,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,164 +17 3293 . C <*> 0 . DP=5;I16=3,2,0,0,196,7710,0,0,300,18000,0,0,79,1805,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,170 +17 3294 . A <*> 0 . DP=5;I16=3,2,0,0,185,6959,0,0,300,18000,0,0,80,1862,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,162 +17 3295 . A <*> 0 . DP=4;I16=3,1,0,0,162,6602,0,0,240,14400,0,0,82,1924,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,143 +17 3296 . G <*> 0 . DP=4;I16=3,1,0,0,159,6345,0,0,240,14400,0,0,83,1939,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,140 +17 3297 . A <*> 0 . DP=4;I16=3,1,0,0,159,6369,0,0,240,14400,0,0,84,1956,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,140 +17 3298 . C <*> 0 . DP=4;I16=3,1,0,0,153,5941,0,0,240,14400,0,0,85,1975,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,135 +17 3299 . C <*> 0 . DP=4;I16=3,1,0,0,160,6414,0,0,240,14400,0,0,86,1996,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,140 +17 3300 . A <*> 0 . DP=4;I16=3,1,0,0,164,6742,0,0,240,14400,0,0,87,2019,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,144 +17 3301 . G <*> 0 . DP=4;I16=3,1,0,0,161,6507,0,0,240,14400,0,0,88,2044,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,141 +17 3302 . C <*> 0 . DP=5;I16=4,1,0,0,189,7235,0,0,300,18000,0,0,89,2071,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,155 +17 3303 . C <*> 0 . DP=5;I16=4,1,0,0,187,7051,0,0,300,18000,0,0,91,2101,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,153 +17 3304 . T <*> 0 . DP=5;I16=4,1,0,0,206,8500,0,0,300,18000,0,0,93,2135,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,167 +17 3305 . G <*> 0 . DP=5;I16=4,1,0,0,186,6948,0,0,300,18000,0,0,95,2173,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,151 +17 3306 . G <*> 0 . DP=5;I16=4,1,0,0,184,6832,0,0,300,18000,0,0,97,2215,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,150 +17 3307 . C <*> 0 . DP=5;I16=4,1,0,0,188,7098,0,0,300,18000,0,0,99,2261,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,153 +17 3308 . C <*> 0 . DP=5;I16=4,1,0,0,184,6890,0,0,300,18000,0,0,101,2311,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,151 +17 3309 . A <*> 0 . DP=5;I16=4,1,0,0,199,7939,0,0,300,18000,0,0,103,2365,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,162 +17 3310 . A <*> 0 . DP=5;I16=4,1,0,0,201,8123,0,0,300,18000,0,0,105,2423,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,164 +17 3311 . C <*> 0 . DP=5;I16=4,1,0,0,191,7391,0,0,300,18000,0,0,107,2485,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,157 +17 3312 . A <*> 0 . DP=5;I16=4,1,0,0,196,7738,0,0,300,18000,0,0,109,2551,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,160 +17 3313 . T <*> 0 . DP=5;I16=4,1,0,0,198,7856,0,0,300,18000,0,0,111,2621,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,161 +17 3314 . G <*> 0 . DP=5;I16=4,1,0,0,197,7831,0,0,300,18000,0,0,112,2644,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,161 +17 3315 . G <*> 0 . DP=5;I16=4,1,0,0,195,7649,0,0,300,18000,0,0,113,2669,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,159 +17 3316 . T <*> 0 . DP=5;I16=3,1,0,0,139,4903,0,0,240,14400,0,0,89,2071,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,122 +17 3317 . G <*> 0 . DP=6;I16=4,2,0,0,202,6978,0,0,360,21600,0,0,115,2725,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,167 +17 3318 . A <*> 0 . DP=6;I16=4,2,0,0,225,8557,0,0,360,21600,0,0,116,2708,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,185 +17 3319 . A <*> 0 . DP=6;I16=4,2,0,0,230,9112,0,0,360,21600,0,0,117,2697,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,188 +17 3320 . A <*> 0 . DP=6;I16=4,2,0,0,219,8503,0,0,360,21600,0,0,118,2692,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,178 +17 3321 . C <*> 0 . DP=6;I16=4,2,0,0,228,8702,0,0,360,21600,0,0,119,2693,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,186 +17 3322 . C <*> 0 . DP=6;I16=4,2,0,0,242,9784,0,0,360,21600,0,0,120,2700,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,198 +17 3323 . C <*> 0 . DP=6;I16=4,2,0,0,246,10108,0,0,360,21600,0,0,121,2713,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,201 +17 3324 . C <*> 0 . DP=6;I16=4,2,0,0,227,8665,0,0,360,21600,0,0,122,2732,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,186 +17 3325 . G <*> 0 . DP=6;I16=4,2,0,0,200,6766,0,0,360,21600,0,0,123,2757,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,163 +17 3326 . T <*> 0 . DP=6;I16=4,2,0,0,228,8706,0,0,360,21600,0,0,124,2788,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,186 +17 3327 . C <*> 0 . DP=6;I16=4,2,0,0,233,9073,0,0,360,21600,0,0,125,2825,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,190 +17 3328 . T <*> 0 . DP=7;I16=5,2,0,0,277,11019,0,0,420,25200,0,0,125,2817,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,213 +17 3329 . A <*> 0 . DP=7;I16=5,2,0,0,273,10661,0,0,420,25200,0,0,126,2814,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,207 +17 3330 . C <*> 0 . DP=7;I16=5,2,0,0,265,10087,0,0,420,25200,0,0,126,2768,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,203 +17 3331 . T <*> 0 . DP=7;I16=5,2,0,0,289,11969,0,0,420,25200,0,0,126,2730,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,224 +17 3332 . A <*> 0 . DP=7;I16=5,2,0,0,275,10819,0,0,420,25200,0,0,126,2700,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,211 +17 3333 . A <*> 0 . DP=8;I16=5,3,0,0,317,12857,0,0,480,28800,0,0,126,2678,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,241 +17 3334 . A <*> 0 . DP=8;I16=5,3,0,0,318,12908,0,0,480,28800,0,0,127,2665,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,241 +17 3335 . A <*> 0 . DP=8;I16=5,3,0,0,316,12884,0,0,480,28800,0,0,128,2662,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,239 +17 3336 . A <*> 0 . DP=8;I16=5,3,0,0,305,11785,0,0,480,28800,0,0,129,2669,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,232 +17 3337 . T <*> 0 . DP=8;I16=5,3,0,0,296,11006,0,0,480,28800,0,0,130,2686,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,224 +17 3338 . A <*> 0 . DP=8;I16=5,3,0,0,285,10199,0,0,480,28800,0,0,131,2713,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,214 +17 3339 . C <*> 0 . DP=8;I16=5,3,0,0,308,11888,0,0,480,28800,0,0,132,2750,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,232 +17 3340 . A <*> 0 . DP=8;I16=5,3,0,0,308,11972,0,0,480,28800,0,0,133,2797,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,233 +17 3341 . A <*> 0 . DP=8;I16=5,3,0,0,311,12313,0,0,480,28800,0,0,134,2854,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,238 +17 3342 . A <*> 0 . DP=8;I16=5,3,0,0,312,12456,0,0,480,28800,0,0,135,2921,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,240 +17 3343 . A <*> 0 . DP=7;I16=4,3,0,0,288,11884,0,0,420,25200,0,0,136,2946,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,231 +17 3344 . A <*> 0 . DP=7;I16=4,3,0,0,283,11479,0,0,420,25200,0,0,137,2977,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,226 +17 3345 . T <*> 0 . DP=7;I16=4,3,0,0,276,10926,0,0,420,25200,0,0,138,3014,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,220 +17 3346 . T <*> 0 . DP=7;I16=4,3,0,0,278,11054,0,0,420,25200,0,0,138,3008,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,221 +17 3347 . A <*> 0 . DP=7;I16=4,3,0,0,284,11564,0,0,420,25200,0,0,138,3010,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,227 +17 3348 . G <*> 0 . DP=7;I16=4,3,0,0,275,10841,0,0,420,25200,0,0,138,3020,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,219 +17 3349 . C <*> 0 . DP=7;I16=4,3,0,0,257,9491,0,0,420,25200,0,0,138,3038,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,205 +17 3350 . C <*> 0 . DP=7;I16=4,3,0,0,273,10843,0,0,420,25200,0,0,138,3064,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,220 +17 3351 . T <*> 0 . DP=7;I16=4,3,0,0,286,11716,0,0,420,25200,0,0,138,3098,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,228 +17 3352 . G <*> 0 . DP=7;I16=4,3,0,0,269,10375,0,0,420,25200,0,0,138,3140,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,214 +17 3353 . G <*> 0 . DP=7;I16=4,3,0,0,268,10312,0,0,420,25200,0,0,138,3190,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,214 +17 3354 . C <*> 0 . DP=7;I16=4,3,0,0,260,9824,0,0,420,25200,0,0,137,3197,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,209 +17 3355 . G <*> 0 . DP=6;I16=4,2,0,0,202,6932,0,0,360,21600,0,0,137,3209,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,166 +17 3356 . T <*> 0 . DP=6;I16=4,2,0,0,241,9683,0,0,360,21600,0,0,137,3225,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,195 +17 3357 . G <*> 0 . DP=6;I16=4,2,0,0,235,9245,0,0,360,21600,0,0,137,3245,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,192 +17 3358 . G <*> 0 . DP=6;I16=4,2,0,0,228,8744,0,0,360,21600,0,0,137,3269,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,187 +17 3359 . T <*> 0 . DP=6;I16=3,2,0,0,185,6969,0,0,300,18000,0,0,125,3125,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,162 +17 3360 . G <*> 0 . DP=6;I16=4,2,0,0,211,7669,0,0,360,21600,0,0,135,3225,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,175 +17 3361 . G <*> 0 . DP=6;I16=4,2,0,0,211,7655,0,0,360,21600,0,0,134,3206,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,175 +17 3362 . C <*> 0 . DP=6;I16=4,2,0,0,210,7526,0,0,360,21600,0,0,133,3189,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,173 +17 3363 . G <*> 0 . DP=6;I16=4,2,0,0,195,6625,0,0,360,21600,0,0,132,3174,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,161 +17 3364 . C <*> 0 . DP=6;I16=4,2,0,0,237,9403,0,0,360,21600,0,0,130,3112,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,194 +17 3365 . A <*> 0 . DP=6;I16=4,2,0,0,232,9030,0,0,360,21600,0,0,128,3054,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,190 +17 3366 . T <*> 0 . DP=6;I16=4,2,0,0,212,7962,0,0,360,21600,0,0,126,3000,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,177 +17 3367 . G <*> 0 . DP=6;I16=4,2,0,0,205,7173,0,0,360,21600,0,0,124,2950,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,169 +17 3368 . C <*> 0 . DP=6;I16=4,2,0,0,232,9012,0,0,360,21600,0,0,122,2904,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,189 +17 3369 . C <*> 0 . DP=6;I16=4,2,0,0,236,9352,0,0,360,21600,0,0,120,2862,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,193 +17 3370 . T <*> 0 . DP=6;I16=3,2,0,0,205,8443,0,0,300,18000,0,0,118,2824,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,178 +17 3371 . G <*> 0 . DP=5;I16=3,2,0,0,195,7619,0,0,300,18000,0,0,117,2789,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,169 +17 3372 . T <*> 0 . DP=5;I16=3,2,0,0,192,7422,0,0,300,18000,0,0,116,2756,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,167 +17 3373 . A <*> 0 . DP=5;I16=3,2,0,0,201,8089,0,0,300,18000,0,0,115,2725,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,174 +17 3374 . A <*> 0 . DP=5;I16=3,2,0,0,188,7246,0,0,300,18000,0,0,114,2696,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,164 +17 3375 . T <*> 0 . DP=5;I16=3,2,0,0,198,7866,0,0,300,18000,0,0,113,2669,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,172 +17 3376 . C <*> 0 . DP=5;I16=3,2,0,0,199,7999,0,0,300,18000,0,0,112,2644,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,173 +17 3377 . C <*> 0 . DP=5;I16=3,2,0,0,200,8008,0,0,300,18000,0,0,111,2621,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,173 +17 3378 . C <*> 0 . DP=5;I16=3,2,0,0,198,7862,0,0,300,18000,0,0,109,2551,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,172 +17 3379 . A <*> 0 . DP=5;I16=3,2,0,0,195,7735,0,0,300,18000,0,0,107,2485,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,169 +17 3380 . G <*> 0 . DP=5;I16=3,2,0,0,206,8502,0,0,300,18000,0,0,105,2423,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,178 +17 3381 . C <*> 0 . DP=5;I16=3,2,0,0,206,8502,0,0,300,18000,0,0,103,2365,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,178 +17 3382 . T <*> 0 . DP=5;I16=3,2,0,0,212,9010,0,0,300,18000,0,0,101,2311,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,184 +17 3383 . A <*> 0 . DP=5;I16=3,2,0,0,192,7396,0,0,300,18000,0,0,99,2261,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,167 +17 3384 . C <*> 0 . DP=6;I16=4,2,0,0,228,8720,0,0,360,21600,0,0,97,2215,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,187 +17 3385 . T <*> 0 . DP=6;I16=4,2,0,0,238,9646,0,0,360,21600,0,0,96,2174,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,195 +17 3386 . T <*> 0 . DP=6;I16=4,2,0,0,230,8866,0,0,360,21600,0,0,95,2139,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,188 +17 3387 . G <*> 0 . DP=7;I16=4,3,0,0,261,9887,0,0,420,25200,0,0,94,2110,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,210 +17 3388 . G <*> 0 . DP=7;I16=4,3,0,0,251,9167,0,0,420,25200,0,0,94,2088,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,202 +17 3389 . G <*> 0 . DP=7;I16=3,4,0,0,259,9653,0,0,420,25200,0,0,95,2073,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,207 +17 3390 . A <*> 0 . DP=7;I16=3,4,0,0,246,8932,0,0,420,25200,0,0,97,2065,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,198 +17 3391 . A <*> 0 . DP=7;I16=3,4,0,0,281,11333,0,0,420,25200,0,0,99,2065,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,224 +17 3392 . G <*> 0 . DP=7;I16=3,4,0,0,271,10519,0,0,420,25200,0,0,101,2073,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,216 +17 3393 . C <*> 0 . DP=7;I16=3,4,0,0,268,10320,0,0,420,25200,0,0,102,2040,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,214 +17 3394 . T <*> 0 . DP=7;I16=3,4,0,0,278,11116,0,0,420,25200,0,0,103,2017,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,222 +17 3395 . G <*> 0 . DP=7;I16=3,4,0,0,278,11050,0,0,420,25200,0,0,104,2004,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,222 +17 3396 . A <*> 0 . DP=7;I16=3,4,0,0,290,12038,0,0,420,25200,0,0,105,2001,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,232 +17 3397 . G <*> 0 . DP=7;I16=3,4,0,0,272,10616,0,0,420,25200,0,0,106,2008,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,218 +17 3398 . G <*> 0 . DP=7;I16=3,4,0,0,271,10501,0,0,420,25200,0,0,107,2025,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,215 +17 3399 . G <*> 0 . DP=7;I16=3,4,0,0,269,10353,0,0,420,25200,0,0,108,2052,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,216 +17 3400 . A <*> 0 . DP=7;I16=3,4,0,0,266,10162,0,0,420,25200,0,0,109,2089,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,213 +17 3401 . T <*> 0 . DP=7;I16=3,4,0,0,270,10470,0,0,420,25200,0,0,110,2136,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,216 +17 3402 . G <*> 0 . DP=7;I16=3,4,0,0,266,10140,0,0,420,25200,0,0,111,2193,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,213 +17 3403 . A <*> 0 . DP=6;I16=2,4,0,0,250,10446,0,0,360,21600,0,0,113,2259,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,205 +17 3404 . G <*> 0 . DP=6;I16=2,4,0,0,227,8687,0,0,360,21600,0,0,114,2284,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,186 +17 3405 . A <*> 0 . DP=6;I16=2,4,0,0,217,8007,0,0,360,21600,0,0,115,2319,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,179 +17 3406 . A <*> 0 . DP=6;I16=2,4,0,0,225,8587,0,0,360,21600,0,0,116,2364,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,186 +17 3407 . C <*> 0 . DP=6;I16=2,4,0,0,223,8377,0,0,360,21600,0,0,117,2419,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,183 +17 3408 . T <*> 0 . DP=6;I16=2,4,0,0,231,8963,0,0,360,21600,0,0,118,2484,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,189 +17 3409 . G <*> 0 . DP=6;I16=2,4,0,0,236,9304,0,0,360,21600,0,0,118,2510,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,192 +17 3410 . C <*> 0 . DP=6;I16=2,4,0,0,213,7767,0,0,360,21600,0,0,117,2497,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,176 +17 3411 . T <*> 0 . DP=6;I16=2,4,0,0,240,9648,0,0,360,21600,0,0,116,2494,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,196 +17 3412 . T <*> 0 . DP=6;I16=2,4,0,0,231,8909,0,0,360,21600,0,0,115,2501,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,189 +17 3413 . G <*> 0 . DP=6;I16=2,4,0,0,226,8538,0,0,360,21600,0,0,113,2467,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,184 +17 3414 . A <*> 0 . DP=6;I16=2,4,0,0,200,6886,0,0,360,21600,0,0,111,2441,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,166 +17 3415 . A <*> 0 . DP=7;I16=2,5,0,0,221,7827,0,0,420,25200,0,0,108,2372,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,179 +17 3416 . C <*> 0 . DP=7;I16=2,5,0,0,244,8750,0,0,420,25200,0,0,106,2310,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,191 +17 3417 . C <*> 0 . DP=7;I16=2,5,0,0,246,8910,0,0,420,25200,0,0,104,2256,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,192 +17 3418 . T <*> 0 . DP=6;I16=2,3,0,0,201,8183,0,0,300,18000,0,0,88,1984,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,176 +17 3419 . G <*> 0 . DP=6;I16=2,4,0,0,233,9083,0,0,360,21600,0,0,102,2168,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,190 +17 3420 . G <*> 0 . DP=6;I16=2,4,0,0,229,8827,0,0,360,21600,0,0,101,2133,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,188 +17 3421 . G <*> 0 . DP=6;I16=2,4,0,0,233,9121,0,0,360,21600,0,0,100,2104,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,191 +17 3422 . A <*> 0 . DP=6;I16=2,4,0,0,223,8877,0,0,360,21600,0,0,99,2081,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,188 +17 3423 . G <*> 0 . DP=6;I16=2,4,0,0,218,8380,0,0,360,21600,0,0,98,2064,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,183 +17 3424 . G <*> 0 . DP=6;I16=2,3,0,0,194,7614,0,0,300,18000,0,0,88,1972,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,169 +17 3425 . C <*> 0 . DP=6;I16=2,4,0,0,226,8644,0,0,360,21600,0,0,96,2048,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,186 +17 3426 . A <*> 0 . DP=6;I16=2,4,0,0,246,10136,0,0,360,21600,0,0,95,2049,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,202 +17 3427 . G <*> 0 . DP=6;I16=2,4,0,0,222,8438,0,0,360,21600,0,0,94,2056,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,184 +17 3428 . A <*> 0 . DP=6;I16=2,4,0,0,213,8019,0,0,360,21600,0,0,93,2069,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,178 +17 3429 . C <*> 0 . DP=5;I16=1,4,0,0,147,4699,0,0,300,18000,0,0,93,2087,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,124 +17 3430 . G <*> 0 . DP=5;I16=1,4,0,0,172,6190,0,0,300,18000,0,0,93,2109,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,144 +17 3431 . T <*> 0 . DP=5;I16=1,4,0,0,202,8244,0,0,300,18000,0,0,93,2135,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,166 +17 3432 . T <*> 0 . DP=5;I16=1,4,0,0,201,8115,0,0,300,18000,0,0,93,2165,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,165 +17 3433 . G <*> 0 . DP=5;I16=1,4,0,0,199,8033,0,0,300,18000,0,0,93,2199,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,164 +17 3434 . C <*> 0 . DP=4;I16=1,3,0,0,155,6027,0,0,240,14400,0,0,94,2236,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,137 +17 3435 . A <*> 0 . DP=4;I16=1,3,0,0,171,7323,0,0,240,14400,0,0,95,2275,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,151 +17 3436 . G <*> 0 . DP=4;I16=1,3,0,0,149,5725,0,0,240,14400,0,0,96,2316,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,133 +17 3437 . T <*> 0 . DP=4;I16=1,3,0,0,149,5673,0,0,240,14400,0,0,97,2359,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,132 +17 3438 . G <*> 0 . DP=4;I16=1,3,0,0,159,6389,0,0,240,14400,0,0,98,2404,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,140 +17 3439 . A <*> 0 . DP=4;I16=1,3,0,0,146,5892,0,0,240,14400,0,0,99,2451,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,132 +17 3440 . G <*> 0 . DP=4;I16=1,3,0,0,147,5655,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,131 +17 3441 . C <*> 0 . DP=4;I16=1,2,0,0,122,4964,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,115 +17 3442 . T <*> 0 . DP=4;I16=1,3,0,0,141,5577,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,128 +17 3443 . G <*> 0 . DP=4;I16=1,3,0,0,155,6075,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,137 +17 3444 . A <*> 0 . DP=4;I16=1,3,0,0,144,5778,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,131 +17 3445 . G <*> 0 . DP=4;I16=1,3,0,0,148,5714,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,132 +17 3446 . A <*> 0 . DP=4;I16=1,3,0,0,146,5580,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,131 +17 3447 . T <*> 0 . DP=4;I16=1,3,0,0,156,6134,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,137 +17 3448 . C <*> 0 . DP=4;I16=1,3,0,0,145,5353,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,128 +17 3449 . A <*> 0 . DP=4;I16=1,3,0,0,133,4665,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,119 +17 3450 . C <*> 0 . DP=4;I16=1,3,0,0,119,3693,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,106 +17 3451 . G <*> 0 . DP=4;I16=1,3,0,0,140,4986,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,123 +17 3452 . C <*> 0 . DP=4;I16=1,3,0,0,145,5355,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,128 +17 3453 . C <*> 0 . DP=4;I16=1,3,0,0,141,5043,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,125 +17 3454 . A <*> 0 . DP=4;I16=1,3,0,0,144,5350,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,128 +17 3455 . C <*> 0 . DP=4;I16=1,3,0,0,143,5239,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,127 +17 3456 . T <*> 0 . DP=4;I16=1,3,0,0,152,5886,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,135 +17 3457 . G <*> 0 . DP=4;I16=1,2,0,0,114,4340,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,107 +17 3458 . C <*> 0 . DP=4;I16=1,3,0,0,141,5087,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,125 +17 3459 . A <*> 0 . DP=4;I16=1,3,0,0,129,4565,0,0,240,14400,0,0,100,2500,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,116 +17 3460 . C <*> 0 . DP=4;I16=1,3,0,0,147,5523,0,0,240,14400,0,0,99,2451,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,131 +17 3461 . T <*> 0 . DP=4;I16=1,3,0,0,149,5861,0,0,240,14400,0,0,98,2404,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,133 +17 3462 . C <*> 0 . DP=4;I16=1,3,0,0,148,5506,0,0,240,14400,0,0,97,2359,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,130 +17 3463 . C <*> 0 . DP=4;I16=1,3,0,0,150,5654,0,0,240,14400,0,0,95,2267,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,132 +17 3464 . A <*> 0 . DP=4;I16=1,3,0,0,162,6566,0,0,240,14400,0,0,93,2179,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,142 +17 3465 . G <*> 0 . DP=4;I16=1,3,0,0,152,5846,0,0,240,14400,0,0,90,2046,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,135 +17 3466 . C <*> 0 . DP=5;I16=2,3,0,0,167,5901,0,0,269,15241,0,0,87,1919,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,15,147 +17 3467 . C <*> 0 . DP=5;I16=2,3,0,0,176,6432,0,0,269,15241,0,0,85,1799,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,15,154 +17 3468 . T <*> 0 . DP=5;I16=2,3,0,0,188,7216,0,0,269,15241,0,0,83,1687,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,15,164 +17 3469 . G <*> 0 . DP=5;I16=2,3,0,0,187,7095,0,0,269,15241,0,0,81,1583,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,15,163 +17 3470 . G <*> 0 . DP=5;I16=2,3,0,0,189,7187,0,0,269,15241,0,0,79,1487,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,15,161 +17 3471 . G <*> 0 . DP=5;I16=2,3,0,0,176,6254,0,0,269,15241,0,0,77,1399,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,15,151 +17 3472 . C <*> 0 . DP=5;I16=2,3,0,0,154,5146,0,0,269,15241,0,0,75,1319,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,15,136 +17 3473 . A <*> 0 . DP=5;I16=2,3,0,0,179,6483,0,0,269,15241,0,0,73,1247,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,15,153 +17 3474 . A <*> 0 . DP=5;I16=2,3,0,0,182,6656,0,0,269,15241,0,0,71,1183,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,15,155 +17 3475 . C <*> 0 . DP=5;I16=2,3,0,0,162,5582,0,0,269,15241,0,0,69,1127,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,15,143 +17 3476 . A <*> 0 . DP=5;I16=2,3,0,0,175,6435,0,0,269,15241,0,0,67,1079,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,15,154 +17 3477 . G <*> 0 . DP=5;I16=2,3,0,0,185,6909,0,0,269,15241,0,0,65,1039,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,15,153 +17 3478 . A <*> 0 . DP=6;I16=2,4,0,0,238,9496,0,0,329,18841,0,0,63,1007,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,18,190 +17 3479 . G <*> 0 . DP=6;I16=2,4,0,0,195,6461,0,0,329,18841,0,0,62,984,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,18,160 +17 3480 . T <*> 0 . DP=6;I16=2,4,0,0,185,6329,0,0,329,18841,0,0,61,971,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,18,155 +17 3481 . A <*> 0 . DP=6;I16=1,4,0,0,181,6603,0,0,300,18000,0,0,45,743,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,148 +17 3482 . A <*> 0 . DP=6;I16=2,4,0,0,221,8411,0,0,329,18841,0,0,59,975,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,18,182 +17 3483 . G <*> 0 . DP=6;I16=2,4,0,0,192,6394,0,0,329,18841,0,0,58,992,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,18,158 +17 3484 . A <*> 0 . DP=6;I16=1,4,0,0,158,5458,0,0,300,18000,0,0,39,695,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,133 +17 3485 . C <*> 0 . DP=5;I16=1,4,0,0,150,4886,0,0,269,15241,0,0,57,1055,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,120 +17 3486 . T <*> 0 . DP=5;I16=1,4,0,0,153,4891,0,0,269,15241,0,0,57,1099,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,128 +17 3487 . C <*> 0 . DP=5;I16=0,4,0,0,118,3614,0,0,240,14400,0,0,36,710,0,0;QS=1,0;MQ0F=0 PL 0,12,92 +17 3488 . T <*> 0 . DP=4;I16=1,3,0,0,110,3222,0,0,209,11641,0,0,58,1210,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,98 +17 3489 . G <*> 0 . DP=4;I16=1,3,0,0,85,1953,0,0,209,11641,0,0,59,1275,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,75 +17 3490 . T <*> 0 . DP=3;I16=1,2,0,0,93,2945,0,0,149,8041,0,0,61,1345,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,85 +17 3491 . C <*> 0 . DP=3;I16=1,2,0,0,83,2325,0,0,149,8041,0,0,62,1370,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,78 +17 3492 . T <*> 0 . DP=3;I16=1,2,0,0,110,4086,0,0,149,8041,0,0,62,1350,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,96 +17 3493 . C <*> 0 . DP=3;I16=1,2,0,0,84,2510,0,0,149,8041,0,0,62,1334,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,80 +17 3494 . A <*> 0 . DP=5;I16=1,3,0,0,140,5044,0,0,209,11641,0,0,62,1322,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,117 +17 3495 . A <*> 0 . DP=5;I16=1,4,0,0,155,5055,0,0,269,15241,0,0,88,1940,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,129 +17 3496 . A <*> 0 . DP=5;I16=1,4,0,0,175,6247,0,0,269,15241,0,0,89,1939,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,138 +17 3497 . A <*> 0 . DP=6;I16=1,5,0,0,203,7299,0,0,329,18841,0,0,90,1944,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,148 +17 3498 . A <*> 0 . DP=6;I16=0,5,0,0,157,5197,0,0,300,18000,0,0,67,1331,0,0;QS=1,0;MQ0F=0 PL 0,15,115 +17 3499 . A <*> 0 . DP=6;I16=1,5,0,0,187,6271,0,0,329,18841,0,0,94,1976,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,144 +17 3500 . A <*> 0 . DP=6;I16=1,5,0,0,193,6559,0,0,329,18841,0,0,96,2004,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,150 +17 3501 . A <*> 0 . DP=6;I16=1,5,0,0,193,6535,0,0,329,18841,0,0,98,2040,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,149 +17 3502 . A <*> 0 . DP=6;I16=1,5,0,0,210,7654,0,0,329,18841,0,0,100,2084,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,154 +17 3503 . A <*> 0 . DP=6;I16=1,5,0,0,200,6930,0,0,329,18841,0,0,102,2136,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,155 +17 3504 . A <*> 0 . DP=6;I16=1,5,0,0,188,6264,0,0,329,18841,0,0,103,2145,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,145 +17 3505 . A <*> 0 . DP=6;I16=1,5,0,0,202,7070,0,0,329,18841,0,0,104,2160,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,156 +17 3506 . A <*> 0 . DP=6;I16=1,5,0,0,206,7216,0,0,329,18841,0,0,105,2181,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,158 +17 3507 . T <*> 0 . DP=6;I16=1,5,0,0,201,7061,0,0,329,18841,0,0,106,2208,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,153 +17 3508 . C <*> 0 . DP=6;I16=0,5,0,0,164,5506,0,0,300,18000,0,0,82,1616,0,0;QS=1,0;MQ0F=0 PL 0,15,119 +17 3509 . A <*> 0 . DP=5;I16=0,5,0,0,171,6123,0,0,300,18000,0,0,83,1655,0,0;QS=1,0;MQ0F=0 PL 0,15,125 +17 3510 . C <*> 0 . DP=5;I16=0,5,0,0,163,5573,0,0,300,18000,0,0,84,1700,0,0;QS=1,0;MQ0F=0 PL 0,15,119 +17 3511 . A <*> 0 . DP=5;I16=0,5,0,0,153,5207,0,0,300,18000,0,0,85,1751,0,0;QS=1,0;MQ0F=0 PL 0,15,115 +17 3512 . C <*> 0 . DP=5;I16=0,5,0,0,184,6822,0,0,300,18000,0,0,86,1808,0,0;QS=1,0;MQ0F=0 PL 0,15,131 +17 3513 . C <*> 0 . DP=5;I16=0,5,0,0,193,7455,0,0,300,18000,0,0,87,1871,0,0;QS=1,0;MQ0F=0 PL 0,15,136 +17 3514 . A <*> 0 . DP=5;I16=0,5,0,0,187,7015,0,0,300,18000,0,0,88,1940,0,0;QS=1,0;MQ0F=0 PL 0,15,132 +17 3515 . T <*> 0 . DP=5;I16=0,5,0,0,175,6251,0,0,300,18000,0,0,89,2015,0,0;QS=1,0;MQ0F=0 PL 0,15,126 +17 3516 . T <*> 0 . DP=5;I16=1,4,0,0,160,5434,0,0,300,18000,0,0,91,2095,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,133 +17 3517 . T <*> 0 . DP=5;I16=1,4,0,0,190,7402,0,0,300,18000,0,0,94,2180,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,153 +17 3518 . T <*> 0 . DP=5;I16=1,4,0,0,171,6127,0,0,300,18000,0,0,97,2271,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,141 +17 3519 . G <*> 0 . DP=5;I16=1,4,0,0,186,7038,0,0,300,18000,0,0,100,2368,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,154 +17 3520 . G <*> 0 . DP=5;I16=1,4,0,0,182,6838,0,0,300,18000,0,0,102,2420,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,151 +17 3521 . C <*> 0 . DP=5;I16=1,4,0,0,172,6182,0,0,300,18000,0,0,104,2476,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,143 +17 3522 . T <*> 0 . DP=5;I16=1,4,0,0,191,7423,0,0,300,18000,0,0,106,2536,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,158 +17 3523 . T <*> 0 . DP=5;I16=1,4,0,0,175,6319,0,0,300,18000,0,0,107,2549,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,145 +17 3524 . C <*> 0 . DP=5;I16=1,4,0,0,186,6934,0,0,300,18000,0,0,107,2515,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,152 +17 3525 . A <*> 0 . DP=5;I16=1,4,0,0,202,8238,0,0,300,18000,0,0,107,2485,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,165 +17 3526 . G <*> 0 . DP=5;I16=1,4,0,0,178,6462,0,0,300,18000,0,0,107,2459,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,147 +17 3527 . A <*> 0 . DP=5;I16=1,4,0,0,194,7536,0,0,300,18000,0,0,107,2437,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,157 +17 3528 . T <*> 0 . DP=5;I16=1,4,0,0,188,7070,0,0,300,18000,0,0,107,2419,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,152 +17 3529 . T <*> 0 . DP=5;I16=1,4,0,0,189,7189,0,0,300,18000,0,0,107,2405,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,154 +17 3530 . G <*> 0 . DP=6;I16=2,4,0,0,214,7662,0,0,360,21600,0,0,107,2395,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,175 +17 3531 . C <*> 0 . DP=6;I16=2,4,0,0,214,7676,0,0,360,21600,0,0,108,2390,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,175 +17 3532 . A <*> 0 . DP=6;I16=2,4,0,0,226,8542,0,0,360,21600,0,0,109,2391,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,184 +17 3533 . T <*> 0 . DP=6;I16=2,4,0,0,215,7781,0,0,360,21600,0,0,110,2398,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,176 +17 3534 . A <*> 0 . DP=6;I16=2,4,0,0,213,7633,0,0,360,21600,0,0,111,2411,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,175 +17 3535 . T <*> 0 . DP=6;I16=2,4,0,0,200,6770,0,0,360,21600,0,0,112,2430,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,164 +17 3536 . C <*> 0 . DP=6;I16=2,4,0,0,221,8183,0,0,360,21600,0,0,113,2455,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,180 +17 3537 . C <*> 0 . DP=6;I16=2,4,0,0,227,8613,0,0,360,21600,0,0,114,2486,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,185 +17 3538 . T <*> 0 . DP=6;I16=2,4,0,0,223,8539,0,0,360,21600,0,0,115,2523,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,185 +17 3539 . C <*> 0 . DP=6;I16=2,4,0,0,207,7591,0,0,360,21600,0,0,116,2566,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,173 +17 3540 . C <*> 0 . DP=6;I16=2,4,0,0,207,7427,0,0,360,21600,0,0,117,2615,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,172 +17 3541 . T <*> 0 . DP=6;I16=2,4,0,0,226,8816,0,0,360,21600,0,0,118,2670,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,187 +17 3542 . G <*> 0 . DP=6;I16=2,4,0,0,206,7510,0,0,360,21600,0,0,118,2680,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,172 +17 3543 . C <*> 0 . DP=6;I16=2,4,0,0,231,8931,0,0,360,21600,0,0,118,2694,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,188 +17 3544 . A <*> 0 . DP=6;I16=2,4,0,0,209,7513,0,0,360,21600,0,0,118,2712,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,173 +17 3545 . A <*> 0 . DP=6;I16=2,4,0,0,239,9611,0,0,360,21600,0,0,118,2734,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,196 +17 3546 . G <*> 0 . DP=6;I16=2,4,0,0,215,7987,0,0,360,21600,0,0,118,2760,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,179 +17 3547 . G <*> 0 . DP=6;I16=2,4,0,0,225,8687,0,0,360,21600,0,0,118,2790,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,187 +17 3548 . A <*> 0 . DP=6;I16=2,4,0,0,216,8006,0,0,360,21600,0,0,118,2824,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,179 +17 3549 . T <*> 0 . DP=5;I16=2,3,0,0,175,6189,0,0,300,18000,0,0,119,2861,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,152 +17 3550 . A <*> 0 . DP=5;I16=2,3,0,0,199,7923,0,0,300,18000,0,0,120,2900,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,173 +17 3551 . T <*> 0 . DP=5;I16=2,3,0,0,186,6994,0,0,300,18000,0,0,121,2941,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,162 +17 3552 . A <*> 0 . DP=5;I16=2,3,0,0,181,6745,0,0,300,18000,0,0,122,2984,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,158 +17 3553 . T <*> 0 . DP=6;I16=2,4,0,0,223,8379,0,0,360,21600,0,0,123,3029,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,183 +17 3554 . A <*> 0 . DP=6;I16=2,4,0,0,217,8035,0,0,360,21600,0,0,124,3028,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,179 +17 3555 . C <*> 0 . DP=6;I16=2,4,0,0,199,6787,0,0,360,21600,0,0,125,3033,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,163 +17 3556 . G <*> 0 . DP=6;I16=2,4,0,0,210,7440,0,0,360,21600,0,0,125,2993,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,173 +17 3557 . C <*> 0 . DP=6;I16=2,4,0,0,200,6950,0,0,360,21600,0,0,125,2957,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,165 +17 3558 . G <*> 0 . DP=6;I16=2,4,0,0,209,7397,0,0,360,21600,0,0,125,2925,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,171 +17 3559 . T <*> 0 . DP=6;I16=2,4,0,0,234,9146,0,0,360,21600,0,0,125,2897,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,192 +17 3560 . G <*> 0 . DP=6;I16=2,4,0,0,237,9417,0,0,360,21600,0,0,125,2873,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,194 +17 3561 . A <*> 0 . DP=6;I16=2,4,0,0,240,9630,0,0,360,21600,0,0,125,2853,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,196 +17 3562 . A <*> 0 . DP=7;I16=3,4,0,0,262,10122,0,0,420,25200,0,0,125,2837,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,213 +17 3563 . A <*> 0 . DP=7;I16=3,4,0,0,268,10448,0,0,420,25200,0,0,126,2826,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,216 +17 3564 . T <*> 0 . DP=7;I16=3,4,0,0,266,10308,0,0,420,25200,0,0,127,2821,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,214 +17 3565 . T <*> 0 . DP=7;I16=3,4,0,0,263,10039,0,0,420,25200,0,0,128,2822,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,212 +17 3566 . C <*> 0 . DP=7;I16=3,4,0,0,260,9918,0,0,420,25200,0,0,129,2829,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,209 +17 3567 . A <*> 0 . DP=7;I16=3,4,0,0,279,11143,0,0,420,25200,0,0,130,2842,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,222 +17 3568 . A <*> 0 . DP=7;I16=3,4,0,0,283,11633,0,0,420,25200,0,0,131,2861,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,228 +17 3569 . G <*> 0 . DP=7;I16=3,4,0,0,251,9275,0,0,420,25200,0,0,132,2886,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,204 +17 3570 . T <*> 0 . DP=7;I16=3,4,0,0,264,10100,0,0,420,25200,0,0,132,2868,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,213 +17 3571 . C <*> 0 . DP=7;I16=3,4,0,0,269,10383,0,0,420,25200,0,0,132,2858,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,215 +17 3572 . A <*> 0 . DP=7;I16=3,4,0,0,273,10723,0,0,420,25200,0,0,132,2856,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,218 +17 3573 . A <*> 0 . DP=7;I16=3,4,0,0,276,10936,0,0,420,25200,0,0,131,2813,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,220 +17 3574 . T <*> 0 . DP=7;I16=3,4,0,0,274,10758,0,0,420,25200,0,0,130,2780,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,218 +17 3575 . G <*> 0 . DP=7;I16=3,4,0,0,263,10063,0,0,420,25200,0,0,129,2757,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,212 +17 3576 . A <*> 0 . DP=7;I16=3,4,0,0,265,10175,0,0,420,25200,0,0,128,2744,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,213 +17 3577 . C <*> 0 . DP=7;I16=3,4,0,0,265,10095,0,0,420,25200,0,0,127,2741,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,211 +17 3578 . A <*> 0 . DP=7;I16=3,4,0,0,269,10463,0,0,420,25200,0,0,126,2748,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,216 +17 3579 . A <*> 0 . DP=6;I16=3,3,0,0,227,8823,0,0,360,21600,0,0,125,2713,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,192 +17 3580 . A <*> 0 . DP=6;I16=3,3,0,0,240,9650,0,0,360,21600,0,0,124,2684,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,201 +17 3581 . T <*> 0 . DP=6;I16=3,3,0,0,238,9490,0,0,360,21600,0,0,123,2661,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,199 +17 3582 . C <*> 0 . DP=6;I16=3,3,0,0,239,9595,0,0,360,21600,0,0,122,2644,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,201 +17 3583 . A <*> 0 . DP=7;I16=4,3,0,0,261,10291,0,0,420,25200,0,0,121,2633,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,213 +17 3584 . G <*> 0 . DP=7;I16=4,3,0,0,256,9928,0,0,420,25200,0,0,121,2629,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,209 +17 3585 . A <*> 0 . DP=8;I16=5,3,0,0,266,9678,0,0,480,28800,0,0,121,2633,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,209 +17 3586 . A <*> 0 . DP=8;I16=5,3,0,0,270,10008,0,0,480,28800,0,0,122,2646,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,213 +17 3587 . G A,<*> 0 . DP=8;I16=0,0,5,3,0,0,269,9925,0,0,480,28800,0,0,123,2669;QS=0,1,0;VDB=0.933643;SGB=-0.651104;MQSB=0.900802;MQ0F=0 PL 212,24,0,212,24,212 +17 3588 . A <*> 0 . DP=8;I16=5,3,0,0,272,10182,0,0,480,28800,0,0,123,2651,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,215 +17 3589 . A <*> 0 . DP=8;I16=5,3,0,0,262,9406,0,0,480,28800,0,0,123,2641,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,206 +17 3590 . A <*> 0 . DP=8;I16=5,3,0,0,268,9810,0,0,480,28800,0,0,123,2639,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,211 +17 3591 . A <*> 0 . DP=8;I16=5,3,0,0,269,9829,0,0,480,28800,0,0,123,2645,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,212 +17 3592 . A <*> 0 . DP=8;I16=5,3,0,0,257,8741,0,0,480,28800,0,0,122,2610,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,199 +17 3593 . A <*> 0 . DP=8;I16=5,3,0,0,257,8621,0,0,480,28800,0,0,121,2585,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,198 +17 3594 . C <*> 0 . DP=8;I16=5,3,0,0,285,10221,0,0,480,28800,0,0,120,2570,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,216 +17 3595 . A <*> 0 . DP=7;I16=5,2,0,0,260,9720,0,0,420,25200,0,0,120,2564,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,199 +17 3596 . T <*> 0 . DP=7;I16=5,2,0,0,237,8595,0,0,420,25200,0,0,120,2566,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,188 +17 3597 . A <*> 0 . DP=7;I16=5,2,0,0,266,10166,0,0,420,25200,0,0,120,2576,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,204 +17 3598 . T <*> 0 . DP=7;I16=6,1,0,0,220,7336,0,0,420,25200,0,0,121,2593,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,162 +17 3599 . A <*> 0 . DP=7;I16=6,1,0,0,255,9473,0,0,420,25200,0,0,123,2617,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,182 +17 3600 . T <*> 0 . DP=7;I16=6,1,0,0,257,9579,0,0,420,25200,0,0,125,2649,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,183 +17 3601 . A <*> 0 . DP=7;I16=6,1,0,0,261,9881,0,0,420,25200,0,0,127,2689,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,186 +17 3602 . T <*> 0 . DP=7;I16=6,1,0,0,240,8648,0,0,420,25200,0,0,129,2737,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,174 +17 3603 . A <*> 0 . DP=8;I16=6,2,0,0,298,11242,0,0,480,28800,0,0,131,2793,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,216 +17 3604 . C <*> 0 . DP=8;I16=6,2,0,0,276,9716,0,0,480,28800,0,0,134,2858,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,201 +17 3605 . G <*> 0 . DP=8;I16=5,2,0,0,224,7404,0,0,420,25200,0,0,115,2449,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,174 +17 3606 . C <*> 0 . DP=9;I16=6,3,0,0,319,11567,0,0,540,32400,0,0,139,2969,0,0;QS=1,0;MQSB=0.924584;MQ0F=0 PL 0,27,231 +17 3607 . A <*> 0 . DP=9;I16=6,3,0,0,321,11705,0,0,540,32400,0,0,142,3018,0,0;QS=1,0;MQSB=0.924584;MQ0F=0 PL 0,27,232 +17 3608 . A <*> 0 . DP=9;I16=5,3,0,0,308,11896,0,0,480,28800,0,0,120,2456,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,232 +17 3609 . A <*> 0 . DP=9;I16=6,3,0,0,328,12274,0,0,540,32400,0,0,147,3107,0,0;QS=1,0;MQSB=0.924584;MQ0F=0 PL 0,27,238 +17 3610 . C <*> 0 . DP=9;I16=5,3,0,0,292,10792,0,0,480,28800,0,0,124,2520,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,221 +17 3611 . C <*> 0 . DP=9;I16=5,3,0,0,310,12062,0,0,480,28800,0,0,125,2519,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,234 +17 3612 . A <*> 0 . DP=9;I16=6,3,0,0,341,13619,0,0,540,32400,0,0,151,3153,0,0;QS=1,0;MQSB=0.924584;MQ0F=0 PL 0,27,251 +17 3613 . G <*> 0 . DP=9;I16=5,3,0,0,294,10906,0,0,480,28800,0,0,127,2547,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,223 +17 3614 . T <*> 0 . DP=9;I16=6,3,0,0,325,12303,0,0,540,32400,0,0,153,3201,0,0;QS=1,0;MQSB=0.924584;MQ0F=0 PL 0,27,237 +17 3615 . A <*> 0 . DP=9;I16=6,3,0,0,334,12778,0,0,540,32400,0,0,154,3240,0,0;QS=1,0;MQSB=0.924584;MQ0F=0 PL 0,27,242 +17 3616 . T <*> 0 . DP=9;I16=6,3,0,0,325,12279,0,0,540,32400,0,0,155,3289,0,0;QS=1,0;MQSB=0.924584;MQ0F=0 PL 0,27,238 +17 3617 . C <*> 0 . DP=8;I16=5,3,0,0,279,10217,0,0,480,28800,0,0,157,3347,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,215 +17 3618 . C <*> 0 . DP=8;I16=5,3,0,0,293,11011,0,0,480,28800,0,0,159,3413,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,225 +17 3619 . T <*> 0 . DP=8;I16=5,3,0,0,312,12390,0,0,480,28800,0,0,161,3487,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,238 +17 3620 . A <*> 0 . DP=8;I16=5,3,0,0,277,9805,0,0,480,28800,0,0,163,3569,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,212 +17 3621 . C <*> 0 . DP=8;I16=5,3,0,0,303,11555,0,0,480,28800,0,0,165,3659,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,230 +17 3622 . T <*> 0 . DP=8;I16=5,3,0,0,321,12935,0,0,480,28800,0,0,167,3757,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,242 +17 3623 . G <*> 0 . DP=8;I16=5,3,0,0,273,9577,0,0,480,28800,0,0,169,3863,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,209 +17 3624 . T <*> 0 . DP=8;I16=5,3,0,0,293,10921,0,0,480,28800,0,0,170,3926,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,224 +17 3625 . G <*> 0 . DP=8;I16=5,3,0,0,288,10520,0,0,480,28800,0,0,171,3995,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,219 +17 3626 . T <*> 0 . DP=9;I16=6,3,0,0,315,11289,0,0,540,32400,0,0,172,4070,0,0;QS=1,0;MQSB=0.924584;MQ0F=0 PL 0,27,229 +17 3627 . G <*> 0 . DP=9;I16=6,3,0,0,314,11036,0,0,540,32400,0,0,174,4152,0,0;QS=1,0;MQSB=0.924584;MQ0F=0 PL 0,27,224 +17 3628 . T <*> 0 . DP=9;I16=6,3,0,0,317,11543,0,0,540,32400,0,0,176,4242,0,0;QS=1,0;MQSB=0.924584;MQ0F=0 PL 0,27,232 +17 3629 . G <*> 0 . DP=9;I16=6,3,0,0,329,12109,0,0,540,32400,0,0,176,4240,0,0;QS=1,0;MQSB=0.924584;MQ0F=0 PL 0,27,235 +17 3630 . T <*> 0 . DP=9;I16=6,3,0,0,304,10838,0,0,540,32400,0,0,176,4246,0,0;QS=1,0;MQSB=0.924584;MQ0F=0 PL 0,27,223 +17 3631 . C <*> 0 . DP=8;I16=4,3,0,0,225,7263,0,0,420,25200,0,0,152,3634,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,179 +17 3632 . G <*> 0 . DP=8;I16=5,3,0,0,233,7367,0,0,480,28800,0,0,177,4227,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,181 +17 3633 . T <*> 0 . DP=8;I16=5,3,0,0,285,10787,0,0,480,28800,0,0,177,4199,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,222 +17 3634 . T <*> 0 . DP=8;I16=5,3,0,0,290,11190,0,0,480,28800,0,0,177,4175,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,227 +17 3635 . T <*> 0 . DP=8;I16=5,3,0,0,293,10913,0,0,480,28800,0,0,177,4155,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,224 +17 3636 . G <*> 0 . DP=8;I16=5,3,0,0,283,10257,0,0,480,28800,0,0,177,4139,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,217 +17 3637 . T <*> 0 . DP=8;I16=5,3,0,0,314,12504,0,0,480,28800,0,0,177,4127,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,240 +17 3638 . T <*> 0 . DP=8;I16=5,3,0,0,288,10660,0,0,480,28800,0,0,176,4070,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,222 +17 3639 . G <*> 0 . DP=9;I16=6,3,0,0,308,10662,0,0,540,32400,0,0,175,4019,0,0;QS=1,0;MQSB=0.924584;MQ0F=0 PL 0,27,221 +17 3640 . T <*> 0 . DP=9;I16=6,3,0,0,315,11283,0,0,540,32400,0,0,175,3975,0,0;QS=1,0;MQSB=0.924584;MQ0F=0 PL 0,27,229 +17 3641 . G <*> 0 . DP=9;I16=6,3,0,0,309,10867,0,0,540,32400,0,0,175,3939,0,0;QS=1,0;MQSB=0.924584;MQ0F=0 PL 0,27,224 +17 3642 . T <*> 0 . DP=9;I16=5,3,0,0,293,11005,0,0,480,28800,0,0,150,3286,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,225 +17 3643 . T <*> 0 . DP=9;I16=6,3,0,0,312,11318,0,0,540,32400,0,0,175,3891,0,0;QS=1,0;MQSB=0.924584;MQ0F=0 PL 0,27,230 +17 3644 . T <*> 0 . DP=9;I16=5,3,0,0,306,11998,0,0,480,28800,0,0,157,3555,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,236 +17 3645 . T <*> 0 . DP=9;I16=6,3,0,0,326,12228,0,0,540,32400,0,0,175,3875,0,0;QS=1,0;MQSB=0.924584;MQ0F=0 PL 0,27,239 +17 3646 . C <*> 0 . DP=9;I16=6,3,0,0,252,7724,0,0,540,32400,0,0,175,3879,0,0;QS=1,0;MQSB=0.924584;MQ0F=0 PL 0,27,188 +17 3647 . G <*> 0 . DP=9;I16=4,3,0,0,212,7088,0,0,420,25200,0,0,125,2641,0,0;QS=1,0;MQSB=1.01283;MQ0F=0 PL 0,21,173 +17 3648 . A <*> 0 . DP=9;I16=5,3,0,0,294,11012,0,0,480,28800,0,0,150,3286,0,0;QS=1,0;MQSB=0.900802;MQ0F=0 PL 0,24,225 +17 3649 . C <*> 0 . DP=9;I16=6,3,0,0,309,10981,0,0,540,32400,0,0,175,3939,0,0;QS=1,0;MQSB=0.924584;MQ0F=0 PL 0,27,226 +17 3650 . A <*> 0 . DP=9;I16=6,3,0,0,335,12925,0,0,540,32400,0,0,175,3975,0,0;QS=1,0;MQSB=0.924584;MQ0F=0 PL 0,27,246 +17 3651 . G <*> 0 . DP=9;I16=6,3,0,0,320,11684,0,0,540,32400,0,0,175,4019,0,0;QS=1,0;MQSB=0.924584;MQ0F=0 PL 0,27,233 +17 3652 . C <*> 0 . DP=9;I16=6,3,0,0,303,10767,0,0,540,32400,0,0,174,4020,0,0;QS=1,0;MQSB=0.924584;MQ0F=0 PL 0,27,225 +17 3653 . T <*> 0 . DP=9;I16=6,3,0,0,329,12273,0,0,540,32400,0,0,173,4027,0,0;QS=1,0;MQSB=0.924584;MQ0F=0 PL 0,27,239 +17 3654 . G <*> 0 . DP=8;I16=4,2,0,0,218,8086,0,0,360,21600,0,0,140,3350,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,180 +17 3655 . T <*> 0 . DP=7;I16=5,2,0,0,222,7766,0,0,420,25200,0,0,166,4006,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,179 +17 3656 . C <*> 0 . DP=7;I16=5,2,0,0,241,8827,0,0,420,25200,0,0,167,4039,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,191 +17 3657 . C <*> 0 . DP=7;I16=5,2,0,0,245,8875,0,0,420,25200,0,0,168,4074,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,192 +17 3658 . G <*> 0 . DP=7;I16=5,2,0,0,204,6582,0,0,420,25200,0,0,169,4111,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,163 +17 3659 . T <*> 0 . DP=7;I16=5,2,0,0,235,8387,0,0,420,25200,0,0,169,4101,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,186 +17 3660 . G <*> 0 . DP=7;I16=4,2,0,0,205,7315,0,0,360,21600,0,0,146,3566,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,171 +17 3661 . T <*> 0 . DP=7;I16=5,2,0,0,234,8550,0,0,420,25200,0,0,168,4044,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,188 +17 3662 . T <*> 0 . DP=7;I16=4,2,0,0,222,8532,0,0,360,21600,0,0,146,3558,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,184 +17 3663 . A <*> 0 . DP=7;I16=4,2,0,0,219,8091,0,0,360,21600,0,0,144,3476,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,180 +17 3664 . T <*> 0 . DP=7;I16=5,2,0,0,250,9272,0,0,420,25200,0,0,165,3927,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,196 +17 3665 . A <*> 0 . DP=7;I16=5,2,0,0,271,10551,0,0,420,25200,0,0,163,3849,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,208 +17 3666 . A <*> 0 . DP=7;I16=5,2,0,0,267,10509,0,0,420,25200,0,0,161,3775,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,208 +17 3667 . T <*> 0 . DP=7;I16=4,2,0,0,232,8996,0,0,360,21600,0,0,143,3449,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,189 +17 3668 . A <*> 0 . DP=7;I16=5,2,0,0,273,10697,0,0,420,25200,0,0,157,3639,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,209 +17 3669 . A <*> 0 . DP=7;I16=5,2,0,0,270,10572,0,0,420,25200,0,0,155,3577,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,209 +17 3670 . T <*> 0 . DP=8;I16=6,2,0,0,305,11743,0,0,480,28800,0,0,153,3519,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,220 +17 3671 . T <*> 0 . DP=8;I16=6,2,0,0,306,11932,0,0,480,28800,0,0,152,3466,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,223 +17 3672 . C <*> 0 . DP=8;I16=5,2,0,0,263,10097,0,0,420,25200,0,0,138,3250,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,205 +17 3673 . C <*> 0 . DP=8;I16=6,2,0,0,304,11654,0,0,480,28800,0,0,138,3234,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,219 +17 3674 . T <*> 0 . DP=8;I16=6,2,0,0,313,12475,0,0,480,28800,0,0,138,3174,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,228 +17 3675 . C <*> 0 . DP=8;I16=6,2,0,0,308,11960,0,0,480,28800,0,0,138,3122,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,222 +17 3676 . T <*> 0 . DP=8;I16=6,2,0,0,320,12888,0,0,480,28800,0,0,138,3078,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,231 +17 3677 . A <*> 0 . DP=8;I16=6,2,0,0,301,11433,0,0,480,28800,0,0,138,3042,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,217 +17 3678 . G <*> 0 . DP=8;I16=6,2,0,0,298,11246,0,0,480,28800,0,0,138,3014,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,216 +17 3679 . T <*> 0 . DP=8;I16=6,2,0,0,316,12560,0,0,480,28800,0,0,137,2945,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,227 +17 3680 . T <*> 0 . DP=8;I16=6,2,0,0,271,9679,0,0,480,28800,0,0,136,2886,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,202 +17 3681 . C <*> 0 . DP=8;I16=6,2,0,0,298,11278,0,0,480,28800,0,0,135,2837,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,217 +17 3682 . A <*> 0 . DP=8;I16=6,2,0,0,305,11753,0,0,480,28800,0,0,133,2749,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,220 +17 3683 . A <*> 0 . DP=8;I16=6,2,0,0,311,12309,0,0,480,28800,0,0,131,2673,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,225 +17 3684 . A <*> 0 . DP=7;I16=5,2,0,0,278,11164,0,0,420,25200,0,0,130,2608,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,215 +17 3685 . T <*> 0 . DP=7;I16=5,2,0,0,270,10488,0,0,420,25200,0,0,129,2553,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,207 +17 3686 . T <*> 0 . DP=7;I16=5,2,0,0,283,11465,0,0,420,25200,0,0,128,2508,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,216 +17 3687 . T <*> 0 . DP=8;I16=5,3,0,0,303,11529,0,0,457,26569,0,0,127,2473,0,0;QS=1,0;MQSB=0.750668;MQ0F=0 PL 0,24,229 +17 3688 . A <*> 0 . DP=8;I16=5,3,0,0,306,11764,0,0,457,26569,0,0,127,2449,0,0;QS=1,0;MQSB=0.750668;MQ0F=0 PL 0,24,232 +17 3689 . T <*> 0 . DP=8;I16=5,3,0,0,308,11936,0,0,457,26569,0,0,127,2437,0,0;QS=1,0;MQSB=0.750668;MQ0F=0 PL 0,24,233 +17 3690 . T <*> 0 . DP=8;I16=5,3,0,0,297,11169,0,0,457,26569,0,0,127,2437,0,0;QS=1,0;MQSB=0.750668;MQ0F=0 PL 0,24,225 +17 3691 . C <*> 0 . DP=8;I16=4,3,0,0,266,10272,0,0,397,22969,0,0,120,2400,0,0;QS=1,0;MQSB=0.810265;MQ0F=0 PL 0,21,214 +17 3692 . A <*> 0 . DP=8;I16=5,3,0,0,271,9827,0,0,457,26569,0,0,127,2473,0,0;QS=1,0;MQSB=0.750668;MQ0F=0 PL 0,24,209 +17 3693 . T <*> 0 . DP=8;I16=5,3,0,0,304,11616,0,0,457,26569,0,0,127,2509,0,0;QS=1,0;MQSB=0.750668;MQ0F=0 PL 0,24,230 +17 3694 . T <*> 0 . DP=8;I16=5,3,0,0,311,12217,0,0,457,26569,0,0,127,2557,0,0;QS=1,0;MQSB=0.750668;MQ0F=0 PL 0,24,234 +17 3695 . T <*> 0 . DP=8;I16=5,3,0,0,307,11897,0,0,457,26569,0,0,127,2617,0,0;QS=1,0;MQSB=0.750668;MQ0F=0 PL 0,24,233 +17 3696 . T <*> 0 . DP=8;I16=5,3,0,0,310,12100,0,0,457,26569,0,0,126,2638,0,0;QS=1,0;MQSB=0.750668;MQ0F=0 PL 0,24,235 +17 3697 . T <*> 0 . DP=8;I16=5,3,0,0,298,11308,0,0,457,26569,0,0,125,2669,0,0;QS=1,0;MQSB=0.750668;MQ0F=0 PL 0,24,229 +17 3698 . A <*> 0 . DP=8;I16=5,3,0,0,301,11441,0,0,457,26569,0,0,124,2710,0,0;QS=1,0;MQSB=0.750668;MQ0F=0 PL 0,24,229 +17 3699 . A <*> 0 . DP=7;I16=4,3,0,0,281,11403,0,0,397,22969,0,0,123,2709,0,0;QS=1,0;MQSB=0.810265;MQ0F=0 PL 0,21,226 +17 3700 . C <*> 0 . DP=8;I16=5,3,0,0,277,9883,0,0,457,26569,0,0,122,2714,0,0;QS=1,0;MQSB=0.750668;MQ0F=0 PL 0,24,212 +17 3701 . T <*> 0 . DP=8;I16=5,3,0,0,302,11782,0,0,457,26569,0,0,122,2726,0,0;QS=1,0;MQSB=0.750668;MQ0F=0 PL 0,24,233 +17 3702 . T <*> 0 . DP=8;I16=5,2,0,0,269,10423,0,0,420,25200,0,0,106,2472,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,207 +17 3703 . C <*> 0 . DP=8;I16=5,3,0,0,303,11597,0,0,457,26569,0,0,120,2678,0,0;QS=1,0;MQSB=0.750668;MQ0F=0 PL 0,24,232 +17 3704 . A <*> 0 . DP=7;I16=5,2,0,0,274,10762,0,0,397,22969,0,0,120,2668,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,21,211 +17 3705 . T <*> 0 . DP=7;I16=5,2,0,0,274,10748,0,0,397,22969,0,0,120,2666,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,21,209 +17 3706 . A <*> 0 . DP=7;I16=5,2,0,0,267,10265,0,0,397,22969,0,0,120,2672,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,21,204 +17 3707 . G <*> 0 . DP=6;I16=5,1,0,0,216,8272,0,0,337,19369,0,0,121,2685,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,168 +17 3708 . T <*> 0 . DP=6;I16=5,0,0,0,195,7643,0,0,300,18000,0,0,101,2263,0,0;QS=1,0;MQ0F=0 PL 0,15,139 +17 3709 . A <*> 0 . DP=6;I16=5,1,0,0,211,7631,0,0,337,19369,0,0,123,2729,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,162 +17 3710 . C <*> 0 . DP=6;I16=5,1,0,0,210,7664,0,0,337,19369,0,0,124,2760,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,159 +17 3711 . C <*> 0 . DP=6;I16=5,1,0,0,229,9019,0,0,337,19369,0,0,125,2797,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,173 +17 3712 . A <*> 0 . DP=6;I16=5,1,0,0,222,8658,0,0,337,19369,0,0,126,2840,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,165 +17 3713 . C <*> 0 . DP=6;I16=5,1,0,0,219,8299,0,0,337,19369,0,0,126,2838,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,164 +17 3714 . A <*> 0 . DP=6;I16=5,1,0,0,230,8914,0,0,337,19369,0,0,126,2840,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,174 +17 3715 . T <*> 0 . DP=6;I16=5,1,0,0,214,7926,0,0,337,19369,0,0,125,2797,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,164 +17 3716 . T <*> 0 . DP=6;I16=5,1,0,0,218,8322,0,0,337,19369,0,0,124,2760,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,164 +17 3717 . C <*> 0 . DP=6;I16=5,1,0,0,222,8600,0,0,337,19369,0,0,123,2729,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,168 +17 3718 . T <*> 0 . DP=6;I16=5,1,0,0,223,9053,0,0,337,19369,0,0,122,2704,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,165 +17 3719 . A <*> 0 . DP=6;I16=5,0,0,0,200,8050,0,0,300,18000,0,0,96,2060,0,0;QS=1,0;MQ0F=0 PL 0,15,142 +17 3720 . C <*> 0 . DP=6;I16=5,1,0,0,212,7920,0,0,337,19369,0,0,120,2672,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,158 +17 3721 . A <*> 0 . DP=6;I16=5,0,0,0,205,8415,0,0,300,18000,0,0,94,2040,0,0;QS=1,0;MQ0F=0 PL 0,15,145 +17 3722 . C <*> 0 . DP=6;I16=5,1,0,0,220,8352,0,0,337,19369,0,0,118,2664,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,165 +17 3723 . A <*> 0 . DP=6;I16=5,0,0,0,205,8419,0,0,300,18000,0,0,92,2044,0,0;QS=1,0;MQ0F=0 PL 0,15,145 +17 3724 . C <*> 0 . DP=6;I16=5,1,0,0,222,8374,0,0,337,19369,0,0,116,2680,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,169 +17 3725 . T <*> 0 . DP=6;I16=5,1,0,0,249,10441,0,0,337,19369,0,0,115,2697,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,190 +17 3726 . G <*> 0 . DP=6;I16=5,1,0,0,215,8133,0,0,337,19369,0,0,113,2669,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,166 +17 3727 . C <*> 0 . DP=5;I16=4,1,0,0,176,6630,0,0,277,15769,0,0,112,2644,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,143 +17 3728 . C <*> 0 . DP=5;I16=4,1,0,0,195,7761,0,0,277,15769,0,0,111,2621,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,160 +17 3729 . C <*> 0 . DP=5;I16=4,1,0,0,201,8161,0,0,277,15769,0,0,110,2600,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,164 +17 3730 . A <*> 0 . DP=5;I16=4,1,0,0,193,7539,0,0,277,15769,0,0,109,2581,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,159 +17 3731 . T <*> 0 . DP=5;I16=4,1,0,0,175,6735,0,0,277,15769,0,0,108,2564,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,139 +17 3732 . G <*> 0 . DP=5;I16=4,1,0,0,185,7171,0,0,277,15769,0,0,107,2549,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,149 +17 3733 . T <*> 0 . DP=5;I16=4,1,0,0,186,6972,0,0,277,15769,0,0,106,2536,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,152 +17 3734 . C <*> 0 . DP=5;I16=4,1,0,0,187,7289,0,0,277,15769,0,0,105,2525,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,152 +17 3735 . C <*> 0 . DP=5;I16=4,1,0,0,188,7314,0,0,277,15769,0,0,104,2516,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,152 +17 3736 . C <*> 0 . DP=6;I16=5,1,0,0,206,7622,0,0,337,19369,0,0,103,2509,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,156 +17 3737 . C <*> 0 . DP=6;I16=5,1,0,0,228,8806,0,0,337,19369,0,0,103,2505,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,175 +17 3738 . T <*> 0 . DP=6;I16=5,1,0,0,248,10312,0,0,337,19369,0,0,103,2505,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,189 +17 3739 . C <*> 0 . DP=6;I16=5,1,0,0,240,9674,0,0,337,19369,0,0,103,2509,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,181 +17 3740 . A <*> 0 . DP=5;I16=4,1,0,0,199,7941,0,0,277,15769,0,0,104,2516,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,163 +17 3741 . A <*> 0 . DP=5;I16=4,1,0,0,214,9172,0,0,277,15769,0,0,105,2525,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,172 +17 3742 . G <*> 0 . DP=5;I16=4,1,0,0,199,8059,0,0,277,15769,0,0,106,2536,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,162 +17 3743 . C <*> 0 . DP=5;I16=4,1,0,0,194,7698,0,0,277,15769,0,0,107,2549,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,158 +17 3744 . T <*> 0 . DP=5;I16=4,1,0,0,202,8358,0,0,277,15769,0,0,108,2564,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,164 +17 3745 . T <*> 0 . DP=5;I16=4,1,0,0,195,7735,0,0,277,15769,0,0,109,2581,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,158 +17 3746 . C <*> 0 . DP=5;I16=4,1,0,0,202,8216,0,0,277,15769,0,0,109,2551,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,165 +17 3747 . C <*> 0 . DP=5;I16=4,1,0,0,199,8039,0,0,277,15769,0,0,109,2525,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,162 +17 3748 . C <*> 0 . DP=5;I16=4,1,0,0,197,7839,0,0,277,15769,0,0,109,2503,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,161 +17 3749 . C <*> 0 . DP=5;I16=4,1,0,0,191,7515,0,0,277,15769,0,0,108,2436,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,154 +17 3750 . T <*> 0 . DP=5;I16=4,1,0,0,183,7365,0,0,277,15769,0,0,107,2375,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,146 +17 3751 . G <*> 0 . DP=5;I16=4,1,0,0,197,7803,0,0,277,15769,0,0,106,2320,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,162 +17 3752 . G <*> 0 . DP=5;I16=4,1,0,0,194,7542,0,0,277,15769,0,0,105,2271,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,159 +17 3753 . C <*> 0 . DP=5;I16=4,1,0,0,200,8068,0,0,277,15769,0,0,104,2228,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,163 +17 3754 . T <*> 0 . DP=5;I16=4,1,0,0,196,8150,0,0,277,15769,0,0,103,2191,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,157 +17 3755 . C <*> 0 . DP=5;I16=4,1,0,0,198,7938,0,0,277,15769,0,0,102,2160,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,161 +17 3756 . C <*> 0 . DP=5;I16=4,1,0,0,196,7876,0,0,277,15769,0,0,101,2135,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,159 +17 3757 . T <*> 0 . DP=5;I16=4,1,0,0,205,8475,0,0,277,15769,0,0,100,2116,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,169 +17 3758 . G <*> 0 . DP=5;I16=4,1,0,0,181,6879,0,0,277,15769,0,0,99,2103,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,147 +17 3759 . C <*> 0 . DP=5;I16=4,0,0,0,165,6815,0,0,240,14400,0,0,73,1471,0,0;QS=1,0;MQ0F=0 PL 0,12,127 +17 3760 . A <*> 0 . DP=6;I16=4,2,0,0,219,8519,0,0,337,19369,0,0,97,2095,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,18,180 +17 3761 . A <*> 0 . DP=6;I16=4,2,0,0,230,9010,0,0,337,19369,0,0,97,2101,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,18,188 +17 3762 . C <*> 0 . DP=6;I16=4,1,0,0,195,7627,0,0,300,18000,0,0,71,1439,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,159 +17 3763 . C <*> 0 . DP=6;I16=4,2,0,0,226,8912,0,0,337,19369,0,0,94,1984,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,18,186 +17 3764 . A <*> 0 . DP=6;I16=4,1,0,0,204,8328,0,0,300,18000,0,0,69,1383,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,167 +17 3765 . C <*> 0 . DP=6;I16=4,2,0,0,231,8935,0,0,337,19369,0,0,90,1848,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,18,189 +17 3766 . A <*> 0 . DP=6;I16=4,2,0,0,234,9192,0,0,337,19369,0,0,88,1792,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,18,191 +17 3767 . A <*> 0 . DP=6;I16=4,2,0,0,232,9038,0,0,337,19369,0,0,86,1744,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,18,191 +17 3768 . A <*> 0 . DP=6;I16=4,2,0,0,239,9569,0,0,337,19369,0,0,84,1704,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,18,195 +17 3769 . T <*> 0 . DP=6;I16=4,2,0,0,235,9227,0,0,337,19369,0,0,82,1672,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,18,191 +17 3770 . C <*> 0 . DP=6;I16=4,2,0,0,219,8165,0,0,337,19369,0,0,80,1648,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,18,180 +17 3771 . T <*> 0 . DP=5;I16=3,2,0,0,180,6964,0,0,277,15769,0,0,79,1631,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,15,157 +17 3772 . A <*> 0 . DP=6;I16=3,3,0,0,190,6442,0,0,337,19369,0,0,78,1620,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,160 +17 3773 . C <*> 0 . DP=6;I16=3,3,0,0,201,7161,0,0,337,19369,0,0,78,1616,0,0;QS=1,0;MQSB=0.861511;MQ0F=0 PL 0,18,171 +17 3774 . T <*> 0 . DP=5;I16=2,3,0,0,204,8394,0,0,277,15769,0,0,79,1619,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL 0,15,178 +17 3775 . C <*> 0 . DP=5;I16=2,2,0,0,156,6124,0,0,240,14400,0,0,68,1484,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,143 +17 3776 . T <*> 0 . DP=5;I16=2,2,0,0,166,6954,0,0,240,14400,0,0,69,1473,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,152 +17 3777 . C <*> 0 . DP=5;I16=2,3,0,0,192,7492,0,0,277,15769,0,0,80,1568,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL 0,15,168 +17 3778 . T <*> 0 . DP=5;I16=2,3,0,0,189,7607,0,0,277,15769,0,0,80,1550,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL 0,15,167 +17 3779 . G <*> 0 . DP=5;I16=2,3,0,0,192,7422,0,0,277,15769,0,0,80,1540,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL 0,15,167 +17 3780 . C <*> 0 . DP=5;I16=2,3,0,0,195,7651,0,0,277,15769,0,0,80,1538,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL 0,15,169 +17 3781 . C <*> 0 . DP=5;I16=2,3,0,0,203,8265,0,0,277,15769,0,0,80,1544,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL 0,15,175 +17 3782 . T <*> 0 . DP=5;I16=2,3,0,0,201,8191,0,0,277,15769,0,0,80,1558,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL 0,15,176 +17 3783 . C <*> 0 . DP=5;I16=2,3,0,0,185,7031,0,0,277,15769,0,0,80,1580,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL 0,15,162 +17 3784 . T <*> 0 . DP=5;I16=2,3,0,0,205,8463,0,0,277,15769,0,0,80,1610,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL 0,15,178 +17 3785 . G <*> 0 . DP=6;I16=2,3,0,0,215,10327,0,0,277,15769,0,0,80,1648,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL 0,15,179 +17 3786 . T <*> 0 . DP=6;I16=2,3,0,0,230,11968,0,0,277,15769,0,0,79,1643,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL 0,15,186 +17 3787 . G <*> 0 . DP=6;I16=2,3,0,0,217,11133,0,0,277,15769,0,0,78,1644,0,0;QS=1,0;MQSB=0.666667;MQ0F=0 PL 0,15,177 +17 3788 . G <*> 0 . DP=5;I16=2,2,0,0,194,10658,0,0,240,14400,0,0,78,1650,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,161 +17 3789 . G <*> 0 . DP=5;I16=2,2,0,0,193,10493,0,0,240,14400,0,0,78,1660,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,161 +17 3790 . T <*> 0 . DP=5;I16=2,2,0,0,187,9851,0,0,240,14400,0,0,78,1674,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,159 +17 3791 . T <*> 0 . DP=5;I16=2,2,0,0,194,10986,0,0,240,14400,0,0,78,1692,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,159 +17 3792 . G <*> 0 . DP=5;I16=2,2,0,0,191,10613,0,0,240,14400,0,0,78,1714,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,157 +17 3793 . A <*> 0 . DP=5;I16=2,2,0,0,196,11250,0,0,240,14400,0,0,78,1740,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,159 +17 3794 . C <*> 0 . DP=5;I16=2,2,0,0,189,10285,0,0,240,14400,0,0,78,1770,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,157 +17 3795 . C <*> 0 . DP=5;I16=2,2,0,0,199,11473,0,0,240,14400,0,0,78,1804,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,161 +17 3796 . T <*> 0 . DP=5;I16=2,2,0,0,203,11871,0,0,240,14400,0,0,78,1842,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,164 +17 3797 . A <*> 0 . DP=5;I16=2,2,0,0,193,10747,0,0,240,14400,0,0,78,1884,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,159 +17 3798 . T <*> 0 . DP=5;I16=2,2,0,0,200,11294,0,0,240,14400,0,0,77,1879,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,165 +17 3799 . T <*> 0 . DP=5;I16=2,2,0,0,199,11571,0,0,240,14400,0,0,76,1876,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,161 +17 3800 . C <*> 0 . DP=5;I16=2,2,0,0,199,11473,0,0,240,14400,0,0,75,1875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,161 +17 3801 . T <*> 0 . DP=4;I16=1,2,0,0,166,10596,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,133 +17 3802 . G <*> 0 . DP=4;I16=1,2,0,0,157,9365,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,130 +17 3803 . G <*> 0 . DP=4;I16=1,2,0,0,152,8664,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,129 +17 3804 . A <*> 0 . DP=4;I16=1,2,0,0,162,10014,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,132 +17 3805 . C <*> 0 . DP=4;I16=1,2,0,0,157,9365,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,130 +17 3806 . A <*> 0 . DP=4;I16=1,2,0,0,154,9054,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,128 +17 3807 . C <*> 0 . DP=4;I16=1,2,0,0,133,7049,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,115 +17 3808 . G <*> 0 . DP=4;I16=1,2,0,0,149,8021,0,0,180,10800,0,0,75,1875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,9,132 +17 3809 . T <*> 0 . DP=5;I16=1,3,0,0,204,11798,0,0,240,14400,0,0,75,1875,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,161 +17 3810 . C <*> 0 . DP=5;I16=1,3,0,0,192,10692,0,0,240,14400,0,0,76,1876,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,153 +17 3811 . A <*> 0 . DP=5;I16=1,3,0,0,200,11382,0,0,240,14400,0,0,77,1879,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,158 +17 3812 . T <*> 0 . DP=5;I16=1,3,0,0,201,11367,0,0,240,14400,0,0,77,1835,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,160 +17 3813 . A <*> 0 . DP=5;I16=1,3,0,0,217,13035,0,0,240,14400,0,0,77,1795,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,170 +17 3814 . G <*> 0 . DP=5;I16=1,3,0,0,204,11530,0,0,240,14400,0,0,77,1759,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,163 +17 3815 . A <*> 0 . DP=5;I16=1,3,0,0,201,11127,0,0,240,14400,0,0,77,1727,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,162 +17 3816 . A <*> 0 . DP=5;I16=1,3,0,0,204,11870,0,0,240,14400,0,0,77,1699,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,160 +17 3817 . A <*> 0 . DP=5;I16=1,3,0,0,197,10661,0,0,240,14400,0,0,77,1675,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,161 +17 3818 . T <*> 0 . DP=5;I16=1,3,0,0,199,10965,0,0,240,14400,0,0,77,1655,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,160 +17 3819 . A <*> 0 . DP=5;I16=1,3,0,0,210,12110,0,0,240,14400,0,0,77,1639,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,167 +17 3820 . G <*> 0 . DP=5;I16=1,3,0,0,195,10747,0,0,240,14400,0,0,77,1627,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,157 +17 3821 . A <*> 0 . DP=5;I16=1,3,0,0,213,12527,0,0,240,14400,0,0,77,1619,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,168 +17 3822 . G <*> 0 . DP=5;I16=1,3,0,0,188,9704,0,0,240,14400,0,0,77,1615,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,157 +17 3823 . T <*> 0 . DP=5;I16=1,3,0,0,200,10910,0,0,240,14400,0,0,77,1615,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,163 +17 3824 . C <*> 0 . DP=5;I16=1,3,0,0,187,9453,0,0,240,14400,0,0,77,1619,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,159 +17 3825 . C <*> 0 . DP=5;I16=1,3,0,0,195,10793,0,0,240,14400,0,0,77,1627,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,157 +17 3826 . T <*> 0 . DP=5;I16=1,3,0,0,197,11361,0,0,240,14400,0,0,77,1639,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,155 +17 3827 . G <*> 0 . DP=5;I16=1,3,0,0,201,11211,0,0,240,14400,0,0,77,1655,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,162 +17 3828 . C <*> 0 . DP=5;I16=1,3,0,0,191,10151,0,0,240,14400,0,0,77,1675,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,157 +17 3829 . A <*> 0 . DP=5;I16=1,3,0,0,197,10899,0,0,240,14400,0,0,77,1699,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,158 +17 3830 . A <*> 0 . DP=5;I16=1,3,0,0,182,9502,0,0,240,14400,0,0,77,1727,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,150 +17 3831 . C <*> 0 . DP=5;I16=1,3,0,0,178,8978,0,0,240,14400,0,0,77,1759,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,149 +17 3832 . A <*> 0 . DP=5;I16=1,3,0,0,172,8972,0,0,240,14400,0,0,77,1795,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,139 +17 3833 . C <*> 0 . DP=5;I16=1,3,0,0,151,6993,0,0,240,14400,0,0,77,1835,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,131 +17 3834 . G <*> 0 . DP=5;I16=1,3,0,0,184,9214,0,0,240,14400,0,0,77,1879,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,156 +17 3835 . T <*> 0 . DP=5;I16=1,3,0,0,181,9167,0,0,240,14400,0,0,76,1876,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,153 +17 3836 . G <*> 0 . DP=6;I16=2,3,0,0,220,10404,0,0,277,15769,0,0,74,1826,0,0;QS=1,0;MQSB=0.5;MQ0F=0 PL 0,15,188 +17 3837 . G <*> 0 . DP=5;I16=1,4,0,0,191,7351,0,0,277,15769,0,0,99,2405,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,157 +17 3838 . C <*> 0 . DP=5;I16=1,4,0,0,179,6571,0,0,277,15769,0,0,99,2363,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,148 +17 3839 . C <*> 0 . DP=5;I16=1,3,0,0,128,4104,0,0,217,12169,0,0,74,1700,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,112 +17 3840 . G <*> 0 . DP=5;I16=1,4,0,0,179,6539,0,0,277,15769,0,0,99,2291,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,146 +17 3841 . T <*> 0 . DP=5;I16=1,4,0,0,197,7779,0,0,277,15769,0,0,99,2261,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,162 +17 3842 . C <*> 0 . DP=5;I16=1,4,0,0,195,7659,0,0,277,15769,0,0,99,2235,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,159 +17 3843 . T <*> 0 . DP=5;I16=1,4,0,0,198,7850,0,0,277,15769,0,0,99,2213,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,159 +17 3844 . G <*> 0 . DP=6;I16=1,5,0,0,227,8615,0,0,337,19369,0,0,99,2195,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,172 +17 3845 . T <*> 0 . DP=6;I16=1,5,0,0,219,8109,0,0,337,19369,0,0,100,2182,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,166 +17 3846 . G <*> 0 . DP=7;I16=1,6,0,0,235,8375,0,0,397,22969,0,0,101,2175,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,172 +17 3847 . T <*> 0 . DP=7;I16=1,6,0,0,268,10292,0,0,397,22969,0,0,103,2175,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,189 +17 3848 . C <*> 0 . DP=7;I16=1,6,0,0,264,10104,0,0,397,22969,0,0,104,2134,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,188 +17 3849 . T <*> 0 . DP=7;I16=1,6,0,0,270,10434,0,0,397,22969,0,0,105,2103,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,190 +17 3850 . G <*> 0 . DP=7;I16=1,6,0,0,259,9691,0,0,397,22969,0,0,106,2082,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,182 +17 3851 . G <*> 0 . DP=7;I16=1,6,0,0,258,9650,0,0,397,22969,0,0,107,2071,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,183 +17 3852 . C <*> 0 . DP=7;I16=1,6,0,0,253,9295,0,0,397,22969,0,0,108,2070,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,179 +17 3853 . T <*> 0 . DP=7;I16=1,6,0,0,269,10669,0,0,397,22969,0,0,109,2079,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,192 +17 3854 . T <*> 0 . DP=7;I16=1,5,0,0,235,9247,0,0,337,19369,0,0,102,2034,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,178 +17 3855 . C <*> 0 . DP=7;I16=1,6,0,0,250,9026,0,0,397,22969,0,0,111,2127,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,175 +17 3856 . T <*> 0 . DP=8;I16=1,6,0,0,264,10058,0,0,397,22969,0,0,112,2166,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,185 +17 3857 . C <*> 0 . DP=8;I16=1,7,0,0,297,11129,0,0,457,26569,0,0,114,2216,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,194 +17 3858 . T <*> 0 . DP=8;I16=1,7,0,0,316,12516,0,0,457,26569,0,0,116,2278,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,208 +17 3859 . C <*> 0 . DP=9;I16=1,7,0,0,235,7137,0,0,457,26569,0,0,118,2352,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,156 +17 3860 . G <*> 0 . DP=9;I16=1,8,0,0,337,12719,0,0,517,30169,0,0,145,3063,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,27,209 +17 3861 . C <*> 0 . DP=8;I16=1,7,0,0,300,11478,0,0,457,26569,0,0,147,3111,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,199 +17 3862 . T <*> 0 . DP=9;I16=1,8,0,0,360,14472,0,0,517,30169,0,0,148,3120,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,27,221 +17 3863 . T <*> 0 . DP=9;I16=1,8,0,0,352,13794,0,0,517,30169,0,0,150,3140,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,27,213 +17 3864 . A <*> 0 . DP=9;I16=1,8,0,0,372,15422,0,0,517,30169,0,0,152,3172,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,27,230 +17 3865 . G <*> 0 . DP=9;I16=1,8,0,0,348,13486,0,0,517,30169,0,0,154,3216,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,27,212 +17 3866 . C <*> 0 . DP=9;I16=1,7,0,0,302,11426,0,0,457,26569,0,0,131,2647,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,197 +17 3867 . A <*> 0 . DP=9;I16=1,8,0,0,310,11252,0,0,517,30169,0,0,158,3340,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,27,195 +17 3868 . T <*> 0 . DP=9;I16=1,8,0,0,360,14450,0,0,517,30169,0,0,160,3420,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,27,221 +17 3869 . C <*> 0 . DP=9;I16=1,8,0,0,343,13105,0,0,517,30169,0,0,162,3512,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,27,211 +17 3870 . T <*> 0 . DP=9;I16=1,8,0,0,347,13485,0,0,517,30169,0,0,163,3565,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,27,211 +17 3871 . T <*> 0 . DP=9;I16=1,8,0,0,364,14740,0,0,517,30169,0,0,164,3628,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,27,223 +17 3872 . G <*> 0 . DP=9;I16=1,8,0,0,328,12090,0,0,517,30169,0,0,164,3650,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,27,200 +17 3873 . T <*> 0 . DP=8;I16=1,7,0,0,323,13061,0,0,457,26569,0,0,165,3679,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,212 +17 3874 . T <*> 0 . DP=8;I16=1,7,0,0,314,12382,0,0,457,26569,0,0,166,3714,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,204 +17 3875 . T <*> 0 . DP=8;I16=1,7,0,0,302,11502,0,0,457,26569,0,0,167,3755,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,197 +17 3876 . C <*> 0 . DP=8;I16=1,7,0,0,280,9892,0,0,457,26569,0,0,168,3802,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,180 +17 3877 . C <*> 0 . DP=8;I16=1,7,0,0,303,11539,0,0,457,26569,0,0,169,3855,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,196 +17 3878 . A <*> 0 . DP=8;I16=1,7,0,0,289,10581,0,0,457,26569,0,0,170,3914,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,188 +17 3879 . A <*> 0 . DP=8;I16=1,7,0,0,315,12649,0,0,457,26569,0,0,171,3979,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,206 +17 3880 . G <*> 0 . DP=8;I16=1,7,0,0,281,9963,0,0,457,26569,0,0,172,4050,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,183 +17 3881 . G <*> 0 . DP=8;I16=1,7,0,0,270,9222,0,0,457,26569,0,0,173,4127,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,174 +17 3882 . T <*> 0 . DP=8;I16=1,6,0,0,251,9125,0,0,397,22969,0,0,148,3534,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,178 +17 3883 . C <*> 0 . DP=8;I16=1,7,0,0,261,8657,0,0,457,26569,0,0,173,4195,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,171 +17 3884 . C <*> 0 . DP=9;I16=2,7,0,0,308,10616,0,0,494,27938,0,0,173,4235,0,0;QS=1,0;MQSB=0;MQ0F=0 PL 0,27,212 +17 3885 . T <*> 0 . DP=9;I16=2,7,0,0,314,11326,0,0,494,27938,0,0,173,4231,0,0;QS=1,0;MQSB=0;MQ0F=0 PL 0,27,214 +17 3886 . C <*> 0 . DP=8;I16=2,6,0,0,258,8768,0,0,434,24338,0,0,174,4234,0,0;QS=1,0;MQSB=0;MQ0F=0 PL 0,24,191 +17 3887 . C <*> 0 . DP=8;I16=2,6,0,0,285,10201,0,0,434,24338,0,0,175,4243,0,0;QS=1,0;MQSB=0;MQ0F=0 PL 0,24,201 +17 3888 . C <*> 0 . DP=8;I16=2,6,0,0,290,10754,0,0,434,24338,0,0,175,4207,0,0;QS=1,0;MQSB=0;MQ0F=0 PL 0,24,208 +17 3889 . A <*> 0 . DP=8;I16=2,6,0,0,297,11309,0,0,434,24338,0,0,175,4175,0,0;QS=1,0;MQSB=0;MQ0F=0 PL 0,24,218 +17 3890 . C <*> 0 . DP=8;I16=2,6,0,0,297,11205,0,0,434,24338,0,0,175,4147,0,0;QS=1,0;MQSB=0;MQ0F=0 PL 0,24,216 +17 3891 . A <*> 0 . DP=9;I16=2,7,0,0,353,13961,0,0,494,27938,0,0,175,4123,0,0;QS=1,0;MQSB=0;MQ0F=0 PL 0,27,239 +17 3892 . G <*> 0 . DP=9;I16=2,7,0,0,310,10796,0,0,494,27938,0,0,176,4104,0,0;QS=1,0;MQSB=0;MQ0F=0 PL 0,27,208 +17 3893 . T <*> 0 . DP=9;I16=2,7,0,0,309,10945,0,0,494,27938,0,0,177,4091,0,0;QS=1,0;MQSB=0;MQ0F=0 PL 0,27,212 +17 3894 . G <*> 0 . DP=9;I16=2,7,0,0,308,10824,0,0,494,27938,0,0,178,4084,0,0;QS=1,0;MQSB=0;MQ0F=0 PL 0,27,208 +17 3895 . T <*> 0 . DP=9;I16=2,7,0,0,327,12143,0,0,494,27938,0,0,179,4083,0,0;QS=1,0;MQSB=0;MQ0F=0 PL 0,27,225 +17 3896 . A <*> 0 . DP=9;I16=2,7,0,0,339,13459,0,0,494,27938,0,0,180,4088,0,0;QS=1,0;MQSB=0;MQ0F=0 PL 0,27,233 +17 3897 . G <*> 0 . DP=10;I16=2,8,0,0,362,13464,0,0,554,31538,0,0,181,4099,0,0;QS=1,0;MQSB=0;MQ0F=0 PL 0,30,234 +17 3898 . C <*> 0 . DP=10;I16=2,8,0,0,381,14613,0,0,554,31538,0,0,183,4117,0,0;QS=1,0;MQSB=0;MQ0F=0 PL 0,30,238 +17 3899 . A <*> 0 . DP=10;I16=2,8,0,0,363,13361,0,0,554,31538,0,0,185,4143,0,0;QS=1,0;MQSB=0;MQ0F=0 PL 0,30,231 +17 3900 . T <*> 0 . DP=10;I16=2,8,0,0,377,14437,0,0,554,31538,0,0,187,4177,0,0;QS=1,0;MQSB=0;MQ0F=0 PL 0,30,240 +17 3901 . G <*> 0 . DP=10;I16=2,7,0,0,322,11624,0,0,494,27938,0,0,164,3594,0,0;QS=1,0;MQSB=0;MQ0F=0 PL 0,27,218 +17 3902 . C <*> 0 . DP=10;I16=2,8,0,0,352,12592,0,0,554,31538,0,0,191,4269,0,0;QS=1,0;MQSB=0;MQ0F=0 PL 0,30,217 +17 3903 . A <*> 0 . DP=11;I16=2,8,0,0,318,10522,0,0,554,31538,0,0,193,4327,0,0;QS=1,0;MQSB=0;MQ0F=0 PL 0,30,204 +17 3904 . C <*> 0 . DP=11;I16=2,8,0,0,381,14651,0,0,554,31538,0,0,193,4377,0,0;QS=1,0;MQSB=0;MQ0F=0 PL 0,30,244 +17 3905 . C <*> 0 . DP=11;I16=2,9,0,0,429,16811,0,0,614,35138,0,0,201,4483,0,0;QS=1,0;MQSB=0;MQ0F=0 PL 0,33,255 +17 3906 . T <*> 0 . DP=11;I16=2,9,0,0,440,17690,0,0,614,35138,0,0,204,4574,0,0;QS=1,0;MQSB=0;MQ0F=0 PL 0,33,253 +17 3907 . G <*> 0 . DP=11;I16=2,9,0,0,413,15733,0,0,614,35138,0,0,207,4675,0,0;QS=1,0;MQSB=0;MQ0F=0 PL 0,33,249 +17 3908 . C <*> 0 . DP=11;I16=2,9,0,0,399,15107,0,0,614,35138,0,0,209,4737,0,0;QS=1,0;MQSB=0;MQ0F=0 PL 0,33,244 +17 3909 . T <*> 0 . DP=11;I16=2,8,0,0,383,14831,0,0,554,31538,0,0,203,4747,0,0;QS=1,0;MQSB=0;MQ0F=0 PL 0,30,237 +17 3910 . A <*> 0 . DP=10;I16=2,8,0,0,351,12613,0,0,554,31538,0,0,213,4845,0,0;QS=1,0;MQSB=0;MQ0F=0 PL 0,30,224 +17 3911 . C <*> 0 . DP=10;I16=2,8,0,0,338,11622,0,0,554,31538,0,0,215,4887,0,0;QS=1,0;MQSB=0;MQ0F=0 PL 0,30,214 +17 3912 . A C,<*> 0 . DP=10;I16=2,7,0,1,319,11431,16,256,494,27938,60,3600,205,4767,11,121;QS=0.951807,0.0481928,0;SGB=-0.379885;RPB=1;MQB=1;MQSB=0;BQB=1;MQ0F=0 PL 0,14,202,27,205,208 +17 3913 . C <*> 0 . DP=10;I16=2,8,0,0,369,14053,0,0,554,31538,0,0,217,4899,0,0;QS=1,0;MQSB=0;MQ0F=0 PL 0,30,234 +17 3914 . T <*> 0 . DP=10;I16=2,8,0,0,364,13634,0,0,554,31538,0,0,218,4920,0,0;QS=1,0;MQSB=0;MQ0F=0 PL 0,30,228 +17 3915 . C <*> 0 . DP=10;I16=2,8,0,0,360,13176,0,0,554,31538,0,0,219,4951,0,0;QS=1,0;MQSB=0;MQ0F=0 PL 0,30,229 +17 3916 . C <*> 0 . DP=10;I16=2,8,0,0,395,15757,0,0,554,31538,0,0,220,4992,0,0;QS=1,0;MQSB=0;MQ0F=0 PL 0,30,251 +17 3917 . T <*> 0 . DP=10;I16=2,8,0,0,408,16764,0,0,554,31538,0,0,220,4992,0,0;QS=1,0;MQSB=0;MQ0F=0 PL 0,30,254 +17 3918 . T <*> 0 . DP=10;I16=2,8,0,0,401,16219,0,0,554,31538,0,0,220,5000,0,0;QS=1,0;MQSB=0;MQ0F=0 PL 0,30,254 +17 3919 . C <*> 0 . DP=10;I16=2,8,0,0,381,14799,0,0,554,31538,0,0,220,5016,0,0;QS=1,0;MQSB=0;MQ0F=0 PL 0,30,242 +17 3920 . T <*> 0 . DP=10;I16=2,8,0,0,402,16318,0,0,554,31538,0,0,219,4991,0,0;QS=1,0;MQSB=0;MQ0F=0 PL 0,30,251 +17 3921 . T <*> 0 . DP=10;I16=2,8,0,0,378,14410,0,0,554,31538,0,0,218,4976,0,0;QS=1,0;MQSB=0;MQ0F=0 PL 0,30,242 +17 3922 . A <*> 0 . DP=10;I16=2,8,0,0,385,14999,0,0,554,31538,0,0,216,4922,0,0;QS=1,0;MQSB=0;MQ0F=0 PL 0,30,244 +17 3923 . G <*> 0 . DP=10;I16=2,8,0,0,381,14653,0,0,554,31538,0,0,213,4829,0,0;QS=1,0;MQSB=0;MQ0F=0 PL 0,30,240 +17 3924 . G <*> 0 . DP=10;I16=2,8,0,0,384,14808,0,0,554,31538,0,0,210,4746,0,0;QS=1,0;MQSB=0;MQ0F=0 PL 0,30,247 +17 3925 . G <*> 0 . DP=10;I16=2,8,0,0,382,14648,0,0,554,31538,0,0,207,4673,0,0;QS=1,0;MQSB=0;MQ0F=0 PL 0,30,245 +17 3926 . C <*> 0 . DP=10;I16=2,8,0,0,374,14196,0,0,554,31538,0,0,204,4610,0,0;QS=1,0;MQSB=0;MQ0F=0 PL 0,30,237 +17 3927 . T <*> 0 . DP=10;I16=2,8,0,0,374,14376,0,0,554,31538,0,0,200,4506,0,0;QS=1,0;MQSB=0;MQ0F=0 PL 0,30,237 +17 3928 . G <*> 0 . DP=10;I16=2,7,0,0,348,13692,0,0,494,27938,0,0,171,3785,0,0;QS=1,0;MQSB=0;MQ0F=0 PL 0,27,233 +17 3929 . A <*> 0 . DP=10;I16=2,8,0,0,342,12106,0,0,554,31538,0,0,192,4322,0,0;QS=1,0;MQSB=0;MQ0F=0 PL 0,30,220 +17 3930 . T <*> 0 . DP=10;I16=2,8,0,0,346,12322,0,0,554,31538,0,0,188,4242,0,0;QS=1,0;MQSB=0;MQ0F=0 PL 0,30,224 +17 3931 . A <*> 0 . DP=10;I16=2,7,0,0,329,12131,0,0,494,27938,0,0,159,3545,0,0;QS=1,0;MQSB=0;MQ0F=0 PL 0,27,222 +17 3932 . T <*> 0 . DP=10;I16=2,8,0,0,353,12985,0,0,554,31538,0,0,179,4057,0,0;QS=1,0;MQSB=0;MQ0F=0 PL 0,30,231 +17 3933 . T <*> 0 . DP=9;I16=2,6,0,0,303,11509,0,0,434,24338,0,0,152,3424,0,0;QS=1,0;MQSB=0;MQ0F=0 PL 0,24,220 +17 3934 . C <*> 0 . DP=9;I16=2,7,0,0,307,10805,0,0,494,27938,0,0,171,3857,0,0;QS=1,0;MQSB=0;MQ0F=0 PL 0,27,209 +17 3935 . C <*> 0 . DP=9;I16=2,7,0,0,253,7679,0,0,494,27938,0,0,167,3769,0,0;QS=1,0;MQSB=0;MQ0F=0 PL 0,27,170 +17 3936 . A G,<*> 0 . DP=9;I16=0,0,1,7,0,0,290,10820,0,0,457,26569,0,0,163,3689;QS=0,1,0;VDB=0.283405;SGB=-0.651104;MQSB=1;MQ0F=0 PL 196,24,0,196,24,196 +17 3937 . C <*> 0 . DP=8;I16=1,7,0,0,238,7390,0,0,457,26569,0,0,160,3616,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,156 +17 3938 . G <*> 0 . DP=8;I16=1,7,0,0,256,8698,0,0,457,26569,0,0,156,3500,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,176 +17 3939 . C <*> 0 . DP=8;I16=1,6,0,0,246,8724,0,0,397,22969,0,0,127,2767,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,174 +17 3940 . A <*> 0 . DP=8;I16=1,6,0,0,224,7816,0,0,397,22969,0,0,123,2667,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,163 +17 3941 . C <*> 0 . DP=8;I16=1,6,0,0,254,9662,0,0,397,22969,0,0,129,2975,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,181 +17 3942 . C <*> 0 . DP=8;I16=1,7,0,0,295,11227,0,0,457,26569,0,0,140,3116,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,195 +17 3943 . T <*> 0 . DP=8;I16=1,7,0,0,292,10930,0,0,457,26569,0,0,136,3040,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,195 +17 3944 . G <*> 0 . DP=8;I16=1,7,0,0,298,11188,0,0,457,26569,0,0,132,2972,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,24,195 +17 3945 . C <*> 0 . DP=7;I16=1,6,0,0,249,9191,0,0,397,22969,0,0,129,2911,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,21,177 +17 3946 . T <*> 0 . DP=7;I16=1,5,0,0,209,7785,0,0,337,19369,0,0,101,2231,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,158 +17 3947 . A <*> 0 . DP=6;I16=1,5,0,0,193,6675,0,0,337,19369,0,0,124,2806,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,149 +17 3948 . C <*> 0 . DP=6;I16=1,5,0,0,202,7182,0,0,337,19369,0,0,122,2760,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,155 +17 3949 . A C,<*> 0 . DP=6;I16=1,3,0,1,140,4966,24,576,217,12169,60,3600,88,2044,25,625;QS=0.850932,0.149068,0;SGB=-0.379885;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0 PL 9,0,107,21,110,124 +17 3950 . C <*> 0 . DP=6;I16=1,5,0,0,217,8159,0,0,337,19369,0,0,118,2680,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,168 +17 3951 . T <*> 0 . DP=6;I16=1,4,0,0,184,7266,0,0,277,15769,0,0,91,2021,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,152 +17 3952 . C <*> 0 . DP=6;I16=1,4,0,0,172,6150,0,0,277,15769,0,0,110,2600,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,143 +17 3953 . C <*> 0 . DP=6;I16=1,5,0,0,219,8051,0,0,337,19369,0,0,112,2590,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,168 +17 3954 . T <*> 0 . DP=6;I16=1,5,0,0,219,8467,0,0,337,19369,0,0,110,2568,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,167 +17 3955 . T <*> 0 . DP=6;I16=1,5,0,0,232,9086,0,0,337,19369,0,0,108,2550,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,174 +17 3956 . C <*> 0 . DP=6;I16=1,5,0,0,217,8207,0,0,337,19369,0,0,106,2536,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,18,167 +17 3957 . T <*> 0 . DP=5;I16=1,4,0,0,203,8339,0,0,277,15769,0,0,105,2525,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,162 +17 3958 . T <*> 0 . DP=5;I16=1,4,0,0,191,7319,0,0,277,15769,0,0,104,2516,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,157 +17 3959 . A <*> 0 . DP=5;I16=1,4,0,0,193,7481,0,0,277,15769,0,0,103,2509,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,154 +17 3960 . T <*> 0 . DP=5;I16=1,4,0,0,172,6168,0,0,277,15769,0,0,101,2455,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,142 +17 3961 . G <*> 0 . DP=5;I16=0,4,0,0,158,6270,0,0,240,14400,0,0,76,1876,0,0;QS=1,0;MQ0F=0 PL 0,12,122 +17 3962 . G <*> 0 . DP=5;I16=1,4,0,0,175,6247,0,0,277,15769,0,0,97,2359,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,15,144 +17 3963 . C <*> 0 . DP=4;I16=1,3,0,0,143,5263,0,0,217,12169,0,0,96,2316,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,126 +17 3964 . T <*> 0 . DP=4;I16=1,3,0,0,157,6207,0,0,217,12169,0,0,95,2275,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,133 +17 3965 . G <*> 0 . DP=4;I16=1,3,0,0,152,5830,0,0,217,12169,0,0,94,2236,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,134 +17 3966 . A <*> 0 . DP=4;I16=1,3,0,0,162,6562,0,0,217,12169,0,0,93,2199,0,0;QS=1,0;MQSB=1;MQ0F=0 PL 0,12,140 +17 3967 . T <*> 0 . DP=4;I16=0,3,0,0,120,4806,0,0,180,10800,0,0,74,1826,0,0;QS=1,0;MQ0F=0 PL 0,9,100 +17 3968 . A <*> 0 . DP=3;I16=0,3,0,0,119,4725,0,0,180,10800,0,0,73,1779,0,0;QS=1,0;MQ0F=0 PL 0,9,99 +17 3969 . T <*> 0 . DP=3;I16=0,3,0,0,129,5549,0,0,180,10800,0,0,72,1734,0,0;QS=1,0;MQ0F=0 PL 0,9,108 +17 3970 . T <*> 0 . DP=3;I16=0,3,0,0,125,5209,0,0,180,10800,0,0,71,1691,0,0;QS=1,0;MQ0F=0 PL 0,9,104 +17 3971 . C <*> 0 . DP=3;I16=0,3,0,0,123,5051,0,0,180,10800,0,0,70,1650,0,0;QS=1,0;MQ0F=0 PL 0,9,103 +17 3972 . C <*> 0 . DP=3;I16=0,3,0,0,114,4358,0,0,180,10800,0,0,69,1611,0,0;QS=1,0;MQ0F=0 PL 0,9,96 +17 3973 . A <*> 0 . DP=3;I16=0,3,0,0,116,4486,0,0,180,10800,0,0,67,1525,0,0;QS=1,0;MQ0F=0 PL 0,9,97 +17 3974 . C <*> 0 . DP=3;I16=0,3,0,0,94,2948,0,0,180,10800,0,0,65,1443,0,0;QS=1,0;MQ0F=0 PL 0,9,78 +17 3975 . G <*> 0 . DP=3;I16=0,3,0,0,115,4417,0,0,180,10800,0,0,63,1365,0,0;QS=1,0;MQ0F=0 PL 0,9,96 +17 3976 . C <*> 0 . DP=3;I16=0,3,0,0,116,4490,0,0,180,10800,0,0,61,1291,0,0;QS=1,0;MQ0F=0 PL 0,9,97 +17 3977 . A <*> 0 . DP=3;I16=0,3,0,0,107,3829,0,0,180,10800,0,0,58,1172,0,0;QS=1,0;MQ0F=0 PL 0,9,90 +17 3978 . C <*> 0 . DP=3;I16=0,3,0,0,123,5051,0,0,180,10800,0,0,55,1059,0,0;QS=1,0;MQ0F=0 PL 0,9,103 +17 3979 . C <*> 0 . DP=3;I16=0,3,0,0,124,5130,0,0,180,10800,0,0,52,952,0,0;QS=1,0;MQ0F=0 PL 0,9,104 +17 3980 . T <*> 0 . DP=3;I16=0,3,0,0,118,4644,0,0,180,10800,0,0,49,851,0,0;QS=1,0;MQ0F=0 PL 0,9,98 +17 3981 . G <*> 0 . DP=3;I16=0,3,0,0,111,4131,0,0,180,10800,0,0,46,756,0,0;QS=1,0;MQ0F=0 PL 0,9,93 +17 3982 . C <*> 0 . DP=3;I16=0,3,0,0,115,4437,0,0,180,10800,0,0,43,667,0,0;QS=1,0;MQ0F=0 PL 0,9,97 +17 3983 . T <*> 0 . DP=3;I16=0,3,0,0,111,4115,0,0,180,10800,0,0,40,584,0,0;QS=1,0;MQ0F=0 PL 0,9,93 +17 3984 . A <*> 0 . DP=3;I16=0,3,0,0,95,3069,0,0,180,10800,0,0,37,507,0,0;QS=1,0;MQ0F=0 PL 0,9,80 +17 3985 . C <*> 0 . DP=3;I16=0,3,0,0,109,3969,0,0,180,10800,0,0,34,436,0,0;QS=1,0;MQ0F=0 PL 0,9,91 +17 3986 . A <*> 0 . DP=3;I16=0,3,0,0,99,3323,0,0,180,10800,0,0,31,371,0,0;QS=1,0;MQ0F=0 PL 0,9,84 +17 3987 . C <*> 0 . DP=3;I16=0,3,0,0,112,4200,0,0,180,10800,0,0,28,312,0,0;QS=1,0;MQ0F=0 PL 0,9,94 +17 3988 . T <*> 0 . DP=3;I16=0,3,0,0,109,3969,0,0,180,10800,0,0,25,259,0,0;QS=1,0;MQ0F=0 PL 0,9,91 +17 3989 . C <*> 0 . DP=3;I16=0,3,0,0,105,3677,0,0,180,10800,0,0,22,212,0,0;QS=1,0;MQ0F=0 PL 0,9,88 +17 3990 . C <*> 0 . DP=3;I16=0,3,0,0,114,4338,0,0,180,10800,0,0,19,171,0,0;QS=1,0;MQ0F=0 PL 0,9,95 +17 3991 . T <*> 0 . DP=3;I16=0,3,0,0,105,3737,0,0,180,10800,0,0,16,136,0,0;QS=1,0;MQ0F=0 PL 0,9,89 +17 3992 . T <*> 0 . DP=2;I16=0,2,0,0,79,3125,0,0,120,7200,0,0,14,106,0,0;QS=1,0;MQ0F=0 PL 0,6,72 +17 3993 . C <*> 0 . DP=2;I16=0,2,0,0,76,2896,0,0,120,7200,0,0,12,80,0,0;QS=1,0;MQ0F=0 PL 0,6,70 +17 3994 . T <*> 0 . DP=2;I16=0,2,0,0,79,3125,0,0,120,7200,0,0,10,58,0,0;QS=1,0;MQ0F=0 PL 0,6,72 +17 3995 . T <*> 0 . DP=2;I16=0,2,0,0,76,2890,0,0,120,7200,0,0,8,40,0,0;QS=1,0;MQ0F=0 PL 0,6,69 +17 3996 . A <*> 0 . DP=2;I16=0,2,0,0,80,3218,0,0,120,7200,0,0,6,26,0,0;QS=1,0;MQ0F=0 PL 0,6,73 +17 3997 . G <*> 0 . DP=2;I16=0,2,0,0,65,2137,0,0,120,7200,0,0,4,16,0,0;QS=1,0;MQ0F=0 PL 0,6,60 +17 3998 . G <*> 0 . DP=1;I16=0,1,0,0,36,1296,0,0,60,3600,0,0,3,9,0,0;QS=1,0;MQ0F=0 PL 0,3,36 +17 3999 . G <*> 0 . DP=1;I16=0,1,0,0,38,1444,0,0,60,3600,0,0,2,4,0,0;QS=1,0;MQ0F=0 PL 0,3,38 +17 4000 . C <*> 0 . DP=1;I16=0,1,0,0,36,1296,0,0,60,3600,0,0,1,1,0,0;QS=1,0;MQ0F=0 PL 0,3,36 +17 4001 . T <*> 0 . 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C <*> 0 . DP=18;I16=17,0,0,0,688,29762,0,0,958,55682,0,0,332,7446,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,189:9:0 0,9,108:3:0 0,15,134:5:0 +17 101 . C <*> 0 . DP=18;I16=17,0,0,0,650,27530,0,0,958,55682,0,0,331,7303,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,182:9:0 0,9,99:3:0 0,15,132:5:0 +17 102 . C <*> 0 . DP=18;I16=17,0,0,0,695,30453,0,0,958,55682,0,0,330,7178,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,188:9:0 0,9,111:3:0 0,15,139:5:0 +17 103 . T <*> 0 . DP=18;I16=16,0,0,0,692,31998,0,0,929,54841,0,0,323,7035,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,189:8:0 0,9,108:3:0 0,15,147:5:0 +17 104 . G <*> 0 . DP=18;I16=15,0,0,0,611,26723,0,0,900,54000,0,0,295,6259,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,24,178:8:0 0,6,89:2:0 0,15,133:5:0 +17 105 . G <*> 0 . DP=19;I16=17,0,0,0,604,23936,0,0,989,58441,0,0,317,6751,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,170:9:0 0,9,97:3:0 0,15,125:5:0 +17 106 . G <*> 0 . DP=19;I16=17,0,0,0,644,26574,0,0,989,58441,0,0,299,6093,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,30,190:10:0 0,6,85:2:0 0,15,124:5:0 +17 107 . C <*> 0 . DP=19;I16=17,0,0,0,694,30064,0,0,989,58441,0,0,313,6543,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,192:9:0 0,9,108:3:0 0,15,136:5:0 +17 108 . C <*> 0 . DP=19;I16=17,0,0,0,692,30148,0,0,989,58441,0,0,310,6420,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,190:9:0 0,9,108:3:0 0,15,135:5:0 +17 109 . T <*> 0 . DP=19;I16=17,0,0,0,741,34273,0,0,989,58441,0,0,307,6319,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,195:9:0 0,9,110:3:0 0,15,150:5:0 +17 110 . G <*> 0 . DP=19;I16=17,0,0,0,704,31276,0,0,989,58441,0,0,304,6240,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,194:9:0 0,9,104:3:0 0,15,136:5:0 +17 111 . G <*> 0 . DP=19;I16=16,0,0,0,584,24362,0,0,929,54841,0,0,272,5416,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,30,167:10:0 0,6,88:2:0 0,12,118:4:0 +17 112 . C <*> 0 . DP=19;I16=17,0,0,0,680,29854,0,0,989,58441,0,0,296,6052,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,191:9:0 0,9,95:3:0 0,15,135:5:0 +17 113 . A <*> 0 . DP=19;I16=16,0,0,0,645,28035,0,0,960,57600,0,0,266,5318,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,176:9:0 0,6,87:2:0 0,15,139:5:0 +17 114 . C <*> 0 . DP=19;I16=17,0,0,0,674,28788,0,0,989,58441,0,0,286,5856,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,27,182:9:0 0,9,103:3:0 0,15,133:5:0 +17 115 . C <*> 0 . DP=21;I16=18,0,0,0,708,30546,0,0,1049,62041,0,0,274,5490,0,0;QS=3,0;MQ0F=0 PL:DP:DV 0,30,189:10:0 0,6,89:2:0 0,18,147:6:0 +17 116 . A <*> 0 . DP=21;I16=17,1,0,0,727,31755,0,0,1049,62041,0,0,253,5079,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,183:9:0 0,6,90:2:0 0,21,175:7:0 +17 117 . G <*> 0 . DP=21;I16=17,1,0,0,712,30478,0,0,1049,62041,0,0,249,5019,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,183:9:0 0,6,85:2:0 0,21,177:7:0 +17 118 . G <*> 0 . DP=20;I16=16,1,0,0,636,26574,0,0,958,55682,0,0,266,5426,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,175:9:0 0,3,60:1:0 0,21,162:7:0 +17 119 . G <*> 0 . DP=19;I16=16,1,0,0,629,26439,0,0,958,55682,0,0,267,5553,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,175:8:0 0,6,73:2:0 0,21,160:7:0 +17 120 . A <*> 0 . DP=19;I16=16,1,0,0,672,29188,0,0,958,55682,0,0,264,5518,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,175:8:0 0,6,83:2:0 0,21,171:7:0 +17 121 . G <*> 0 . DP=19;I16=16,1,0,0,662,28460,0,0,958,55682,0,0,260,5454,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,181:8:0 0,6,80:2:0 0,21,168:7:0 +17 122 . C <*> 0 . DP=20;I16=17,1,0,0,716,31224,0,0,1018,59282,0,0,256,5410,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,181:8:0 0,9,99:3:0 0,21,178:7:0 +17 123 . T <*> 0 . DP=18;I16=15,1,0,0,661,29997,0,0,898,52082,0,0,255,5385,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,167:7:0 0,9,112:3:0 0,18,166:6:0 +17 124 . T <*> 0 . DP=19;I16=17,1,0,0,626,24802,0,0,987,56523,0,0,279,6003,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,27,154:9:0 0,9,104:3:0 0,18,154:6:0 +17 125 . A <*> 0 . DP=18;I16=15,1,0,0,611,25689,0,0,898,52082,0,0,254,5340,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,154:7:0 0,9,104:3:0 0,18,162:6:0 +17 126 . A <*> 0 . DP=18;I16=16,1,0,0,648,27366,0,0,927,52923,0,0,279,5947,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,162:8:0 0,9,107:3:0 0,18,174:6:0 +17 127 . C <*> 0 . DP=18;I16=16,1,0,0,646,26972,0,0,927,52923,0,0,279,5949,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,163:8:0 0,9,109:3:0 0,18,160:6:0 +17 128 . A <*> 0 . DP=18;I16=16,1,0,0,673,28797,0,0,927,52923,0,0,279,5971,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,169:8:0 0,9,111:3:0 0,18,162:6:0 +17 129 . A <*> 0 . DP=17;I16=15,1,0,0,645,27891,0,0,867,49323,0,0,280,6012,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,168:8:0 0,9,113:3:0 0,15,159:5:0 +17 130 . A <*> 0 . DP=17;I16=15,1,0,0,641,27295,0,0,867,49323,0,0,281,6071,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,24,169:8:0 0,9,113:3:0 0,15,152:5:0 +17 131 . C <*> 0 . DP=16;I16=14,1,0,0,606,25732,0,0,838,48482,0,0,256,5472,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,167:7:0 0,9,110:3:0 0,15,147:5:0 +17 132 . A <*> 0 . DP=16;I16=14,1,0,0,627,27579,0,0,838,48482,0,0,256,5514,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,169:7:0 0,9,110:3:0 0,15,151:5:0 +17 133 . T <*> 0 . DP=15;I16=13,2,0,0,584,22816,0,0,838,48482,0,0,282,6196,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,163:7:0 0,9,105:3:0 0,15,150:5:0 +17 134 . C <*> 0 . DP=15;I16=13,2,0,0,607,24653,0,0,838,48482,0,0,283,6267,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,177:7:0 0,9,105:3:0 0,15,152:5:0 +17 135 . T <*> 0 . DP=15;I16=13,2,0,0,600,24178,0,0,838,48482,0,0,284,6352,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,173:7:0 0,9,106:3:0 0,15,156:5:0 +17 136 . G <*> 0 . DP=15;I16=13,2,0,0,574,22258,0,0,838,48482,0,0,286,6450,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,172:7:0 0,9,105:3:0 0,15,134:5:0 +17 137 . T <*> 0 . DP=15;I16=13,2,0,0,563,21377,0,0,838,48482,0,0,289,6561,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,160:7:0 0,9,104:3:0 0,15,139:5:0 +17 138 . C <*> 0 . DP=15;I16=13,2,0,0,584,23088,0,0,838,48482,0,0,291,6637,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,172:7:0 0,9,108:3:0 0,15,142:5:0 +17 139 . C <*> 0 . DP=15;I16=13,2,0,0,554,20790,0,0,838,48482,0,0,292,6680,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,161:7:0 0,9,106:3:0 0,15,143:5:0 +17 140 . A <*> 0 . DP=15;I16=13,2,0,0,583,22789,0,0,838,48482,0,0,292,6690,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV 0,21,163:7:0 0,9,107:3:0 0,15,153:5:0 +17 141 . G <*> 0 . DP=14;I16=12,2,0,0,534,20750,0,0,778,44882,0,0,292,6664,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,158:6:0 0,9,108:3:0 0,15,142:5:0 +17 142 . C <*> 0 . DP=14;I16=12,2,0,0,503,18593,0,0,778,44882,0,0,292,6650,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,157:6:0 0,9,97:3:0 0,15,129:5:0 +17 143 . G <*> 0 . DP=14;I16=11,2,0,0,415,13657,0,0,718,41282,0,0,285,6599,0,0;QS=3,0;MQSB=0.590909;MQ0F=0 PL:DP:DV 0,18,128:6:0 0,9,95:3:0 0,12,97:4:0 +17 144 . A <*> 0 . DP=14;I16=12,2,0,0,519,19725,0,0,778,44882,0,0,291,6609,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,152:6:0 0,9,105:3:0 0,15,129:5:0 +17 145 . A <*> 0 . DP=14;I16=12,2,0,0,527,20289,0,0,778,44882,0,0,290,6584,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,153:6:0 0,9,106:3:0 0,15,138:5:0 +17 146 . T <*> 0 . DP=14;I16=12,2,0,0,514,19484,0,0,778,44882,0,0,289,6573,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,152:6:0 0,9,103:3:0 0,15,128:5:0 +17 147 . A <*> 0 . DP=14;I16=12,2,0,0,515,19213,0,0,778,44882,0,0,288,6576,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,150:6:0 0,9,99:3:0 0,15,140:5:0 +17 148 . C <*> 0 . DP=14;I16=12,2,0,0,541,21019,0,0,778,44882,0,0,286,6542,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,157:6:0 0,9,106:3:0 0,15,146:5:0 +17 149 . C <*> 0 . DP=14;I16=12,2,0,0,512,19326,0,0,778,44882,0,0,283,6471,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV 0,18,148:6:0 0,9,109:3:0 0,15,140:5:0 +17 150 . T <*> 0 . DP=13;I16=11,2,0,0,511,20251,0,0,749,44041,0,0,280,6362,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,153:6:0 0,6,84:2:0 0,15,152:5:0 +17 151 . G <*> 0 . DP=13;I16=11,2,0,0,506,19826,0,0,749,44041,0,0,277,6263,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,157:6:0 0,6,84:2:0 0,15,144:5:0 +17 152 . C <*> 0 . DP=14;I16=12,2,0,0,543,21283,0,0,809,47641,0,0,274,6174,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,168:7:0 0,6,84:2:0 0,15,146:5:0 +17 153 . A <*> 0 . DP=14;I16=12,2,0,0,536,20594,0,0,809,47641,0,0,272,6096,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,156:7:0 0,6,81:2:0 0,15,153:5:0 +17 154 . T <*> 0 . DP=14;I16=12,2,0,0,523,20051,0,0,809,47641,0,0,270,6030,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,159:7:0 0,6,83:2:0 0,15,139:5:0 +17 155 . C <*> 0 . DP=14;I16=12,2,0,0,542,21254,0,0,809,47641,0,0,268,5976,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,172:7:0 0,6,85:2:0 0,15,139:5:0 +17 156 . C <*> 0 . DP=14;I16=12,2,0,0,536,20884,0,0,809,47641,0,0,266,5934,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,163:7:0 0,6,84:2:0 0,15,150:5:0 +17 157 . C <*> 0 . DP=14;I16=12,2,0,0,555,22081,0,0,809,47641,0,0,264,5904,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,169:7:0 0,6,85:2:0 0,15,149:5:0 +17 158 . T <*> 0 . DP=14;I16=12,2,0,0,568,23154,0,0,809,47641,0,0,262,5886,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,170:7:0 0,6,84:2:0 0,15,159:5:0 +17 159 . A <*> 0 . DP=15;I16=12,2,0,0,519,19467,0,0,809,47641,0,0,260,5880,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,157:7:0 0,6,83:2:0 0,15,135:5:0 +17 160 . G <*> 0 . DP=15;I16=13,2,0,0,547,20633,0,0,869,51241,0,0,259,5887,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,165:7:0 0,6,85:2:0 0,18,139:6:0 +17 161 . A <*> 0 . DP=15;I16=13,2,0,0,568,21610,0,0,869,51241,0,0,258,5908,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,157:7:0 0,6,83:2:0 0,18,162:6:0 +17 162 . A <*> 0 . DP=15;I16=13,2,0,0,557,21139,0,0,869,51241,0,0,255,5843,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,147:7:0 0,6,87:2:0 0,18,167:6:0 +17 163 . G <*> 0 . DP=14;I16=12,2,0,0,503,18645,0,0,809,47641,0,0,253,5791,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,21,153:7:0 0,6,79:2:0 0,15,138:5:0 +17 164 . T <*> 0 . DP=14;I16=12,2,0,0,460,15968,0,0,809,47641,0,0,252,5750,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,131:6:0 0,6,79:2:0 0,18,136:6:0 +17 165 . G <*> 0 . DP=14;I16=10,2,0,0,456,17460,0,0,689,40441,0,0,226,5094,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,149:6:0 0,6,80:2:0 0,12,122:4:0 +17 166 . A <*> 0 . DP=14;I16=11,2,0,0,496,19138,0,0,749,44041,0,0,227,5077,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,145:6:0 0,6,82:2:0 0,15,148:5:0 +17 167 . A <*> 0 . DP=14;I16=11,2,0,0,477,17851,0,0,749,44041,0,0,227,5071,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,132:6:0 0,6,86:2:0 0,15,147:5:0 +17 168 . G <*> 0 . DP=14;I16=12,2,0,0,481,18015,0,0,809,47641,0,0,252,5702,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,18,145:6:0 0,6,82:2:0 0,18,140:6:0 +17 169 . C <*> 0 . DP=13;I16=10,2,0,0,402,14224,0,0,689,40441,0,0,227,5045,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,15,106:5:0 0,6,76:2:0 0,15,145:5:0 +17 170 . C <*> 0 . DP=13;I16=11,2,0,0,447,16383,0,0,749,44041,0,0,251,5601,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,15,128:5:0 0,6,80:2:0 0,18,143:6:0 +17 171 . A <*> 0 . DP=13;I16=11,2,0,0,500,19366,0,0,749,44041,0,0,250,5546,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,15,134:5:0 0,6,81:2:0 0,18,166:6:0 +17 172 . C <*> 0 . DP=13;I16=10,2,0,0,439,16395,0,0,689,40441,0,0,241,5441,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,15,138:5:0 0,6,75:2:0 0,15,129:5:0 +17 173 . C <*> 0 . DP=13;I16=11,2,0,0,435,15225,0,0,749,44041,0,0,248,5478,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV 0,15,121:5:0 0,6,76:2:0 0,18,146:6:0 +17 174 . G <*> 0 . DP=13;I16=11,1,0,0,351,10685,0,0,689,40441,0,0,238,5364,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,15,111:5:0 0,3,27:1:0 0,18,117:6:0 +17 175 . C <*> 0 . DP=14;I16=13,1,0,0,511,19161,0,0,809,47641,0,0,249,5463,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,143:6:0 0,3,41:1:0 0,21,175:7:0 +17 176 . C <*> 0 . DP=14;I16=13,1,0,0,489,17733,0,0,809,47641,0,0,251,5477,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,146:6:0 0,3,44:1:0 0,21,152:7:0 +17 177 . C <*> 0 . DP=14;I16=13,1,0,0,488,17328,0,0,809,47641,0,0,253,5507,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,138:6:0 0,3,44:1:0 0,21,158:7:0 +17 178 . A <*> 0 . DP=14;I16=13,1,0,0,519,19485,0,0,809,47641,0,0,254,5502,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,147:6:0 0,3,42:1:0 0,21,172:7:0 +17 179 . A <*> 0 . DP=14;I16=13,1,0,0,478,17278,0,0,809,47641,0,0,255,5511,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,134:6:0 0,3,44:1:0 0,21,170:7:0 +17 180 . A <*> 0 . DP=14;I16=12,1,0,0,425,14653,0,0,749,44041,0,0,250,5498,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,126:6:0 0,3,43:1:0 0,18,148:6:0 +17 181 . G <*> 0 . DP=14;I16=11,1,0,0,450,17152,0,0,689,40441,0,0,233,5233,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,156:6:0 0,3,41:1:0 0,15,138:5:0 +17 182 . A <*> 0 . DP=15;I16=14,1,0,0,515,18235,0,0,869,51241,0,0,258,5622,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,150:7:0 0,3,43:1:0 0,21,159:7:0 +17 183 . C <*> 0 . DP=15;I16=13,1,0,0,483,17419,0,0,809,47641,0,0,235,5063,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,159:7:0 0,3,40:1:0 0,18,139:6:0 +17 184 . A <*> 0 . DP=15;I16=14,1,0,0,535,19667,0,0,869,51241,0,0,262,5770,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,158:7:0 0,3,41:1:0 0,21,163:7:0 +17 185 . C <*> 0 . DP=15;I16=13,1,0,0,487,17295,0,0,809,47641,0,0,238,5192,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,21,150:7:0 0,3,38:1:0 0,18,160:6:0 +17 186 . G <*> 0 . DP=15;I16=12,1,0,0,381,11429,0,0,749,44041,0,0,239,5253,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,117:6:0 0,3,32:1:0 0,18,124:6:0 +17 187 . C <*> 0 . DP=14;I16=13,1,0,0,511,18979,0,0,809,47641,0,0,266,5952,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,147:6:0 0,3,38:1:0 0,21,172:7:0 +17 188 . C <*> 0 . DP=14;I16=13,1,0,0,496,18042,0,0,809,47641,0,0,267,5989,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,18,147:6:0 0,3,37:1:0 0,21,162:7:0 +17 189 . C <*> 0 . DP=15;I16=13,2,0,0,552,20504,0,0,838,48482,0,0,268,6040,0,0;QS=3,0;MQSB=0;MQ0F=0 PL:DP:DV 0,18,152:6:0 0,6,67:2:0 0,21,167:7:0 +17 190 . A <*> 0 . DP=15;I16=12,2,0,0,500,18230,0,0,778,44882,0,0,243,5381,0,0;QS=3,0;MQSB=0;MQ0F=0 PL:DP:DV 0,18,138:6:0 0,6,68:2:0 0,18,159:6:0 +17 191 . T <*> 0 . DP=15;I16=13,2,0,0,534,19276,0,0,838,48482,0,0,267,5939,0,0;QS=3,0;MQSB=0;MQ0F=0 PL:DP:DV 0,18,143:6:0 0,6,67:2:0 0,21,169:7:0 +17 192 . G <*> 0 . DP=15;I16=13,2,0,0,499,17439,0,0,838,48482,0,0,266,5890,0,0;QS=3,0;MQSB=0;MQ0F=0 PL:DP:DV 0,18,143:6:0 0,6,67:2:0 0,21,151:7:0 +17 193 . T <*> 0 . DP=15;I16=13,2,0,0,505,17811,0,0,838,48482,0,0,265,5859,0,0;QS=3,0;MQSB=0;MQ0F=0 PL:DP:DV 0,18,140:6:0 0,6,63:2:0 0,21,157:7:0 +17 194 . C <*> 0 . DP=14;I16=12,2,0,0,467,16569,0,0,778,44882,0,0,265,5845,0,0;QS=3,0;MQSB=0;MQ0F=0 PL:DP:DV 0,18,142:6:0 0,6,67:2:0 0,18,145:6:0 +17 195 . C <*> 0 . DP=14;I16=11,3,0,0,503,18647,0,0,747,42123,0,0,266,5846,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,18,159:6:0 0,6,71:2:0 0,18,160:6:0 +17 196 . A <*> 0 . DP=14;I16=11,3,0,0,482,17400,0,0,747,42123,0,0,268,5862,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,18,166:6:0 0,6,69:2:0 0,18,138:6:0 +17 197 . G <*> 0 . DP=14;I16=11,3,0,0,481,17391,0,0,747,42123,0,0,270,5894,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,18,164:6:0 0,6,68:2:0 0,18,134:6:0 +17 198 . C <*> 0 . DP=14;I16=11,3,0,0,539,20957,0,0,747,42123,0,0,271,5893,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,18,172:6:0 0,6,70:2:0 0,18,164:6:0 +17 199 . T <*> 0 . DP=14;I16=11,3,0,0,505,19197,0,0,747,42123,0,0,271,5861,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,18,162:6:0 0,6,73:2:0 0,18,154:6:0 +17 200 . T <*> 0 . DP=15;I16=11,4,0,0,544,19918,0,0,776,42964,0,0,270,5798,0,0;QS=3,0;MQSB=0.0161635;MQ0F=0 PL:DP:DV 0,18,161:6:0 0,9,89:3:0 0,18,154:6:0 +17 201 . A <*> 0 . DP=16;I16=12,4,0,0,568,20416,0,0,836,46564,0,0,269,5703,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,171:7:0 0,9,89:3:0 0,18,157:6:0 +17 202 . A <*> 0 . DP=16;I16=12,4,0,0,566,20590,0,0,836,46564,0,0,269,5627,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,178:7:0 0,9,84:3:0 0,18,163:6:0 +17 203 . C <*> 0 . DP=16;I16=12,4,0,0,557,20119,0,0,836,46564,0,0,269,5571,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,166:7:0 0,9,90:3:0 0,18,153:6:0 +17 204 . C <*> 0 . DP=16;I16=12,4,0,0,591,22379,0,0,836,46564,0,0,269,5535,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,173:7:0 0,9,91:3:0 0,18,163:6:0 +17 205 . T <*> 0 . DP=16;I16=12,4,0,0,635,25281,0,0,836,46564,0,0,269,5519,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,188:7:0 0,9,95:3:0 0,18,173:6:0 +17 206 . G <*> 0 . DP=16;I16=12,4,0,0,577,21337,0,0,836,46564,0,0,269,5523,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,180:7:0 0,9,89:3:0 0,18,143:6:0 +17 207 . C <*> 0 . DP=16;I16=12,4,0,0,574,21076,0,0,836,46564,0,0,269,5547,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,179:7:0 0,9,93:3:0 0,18,151:6:0 +17 208 . A <*> 0 . DP=16;I16=12,4,0,0,576,21486,0,0,836,46564,0,0,268,5540,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,184:7:0 0,9,93:3:0 0,18,154:6:0 +17 209 . T <*> 0 . DP=16;I16=12,4,0,0,567,20475,0,0,836,46564,0,0,267,5551,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,173:7:0 0,9,91:3:0 0,18,146:6:0 +17 210 . C <*> 0 . DP=16;I16=12,4,0,0,577,21109,0,0,836,46564,0,0,266,5580,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,185:7:0 0,9,92:3:0 0,18,151:6:0 +17 211 . C <*> 0 . DP=16;I16=12,4,0,0,563,20227,0,0,836,46564,0,0,265,5627,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,172:7:0 0,9,92:3:0 0,18,153:6:0 +17 212 . C <*> 0 . DP=16;I16=12,4,0,0,589,22179,0,0,836,46564,0,0,263,5643,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,181:7:0 0,9,92:3:0 0,18,152:6:0 +17 213 . T <*> 0 . DP=16;I16=12,4,0,0,598,22838,0,0,836,46564,0,0,262,5678,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV 0,21,181:7:0 0,9,95:3:0 0,18,165:6:0 +17 214 . A <*> 0 . DP=16;I16=11,4,0,0,529,19401,0,0,776,42964,0,0,240,5248,0,0;QS=3,0;MQSB=0.0161635;MQ0F=0 PL:DP:DV 0,21,176:7:0 0,9,92:3:0 0,15,118:5:0 +17 215 . G <*> 0 . DP=15;I16=12,3,0,0,521,19073,0,0,807,45723,0,0,262,5754,0,0;QS=3,0;MQSB=0.0342181;MQ0F=0 PL:DP:DV 0,21,185:7:0 0,9,90:3:0 0,15,105:5:0 +17 216 . A <*> 0 . DP=14;I16=10,3,0,0,464,16900,0,0,687,38523,0,0,238,5166,0,0;QS=3,0;MQSB=0.040184;MQ0F=0 PL:DP:DV 0,21,173:7:0 0,9,92:3:0 0,9,81:3:0 +17 217 . A <*> 0 . DP=14;I16=11,3,0,0,515,19433,0,0,747,42123,0,0,264,5842,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,21,181:7:0 0,9,90:3:0 0,12,97:4:0 +17 218 . G <*> 0 . DP=14;I16=11,3,0,0,507,18957,0,0,747,42123,0,0,265,5907,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,21,178:7:0 0,9,90:3:0 0,12,110:4:0 +17 219 . T <*> 0 . DP=14;I16=11,3,0,0,470,16286,0,0,747,42123,0,0,266,5986,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,21,173:7:0 0,9,88:3:0 0,12,89:4:0 +17 220 . G <*> 0 . DP=14;I16=10,3,0,0,485,18307,0,0,687,38523,0,0,242,5454,0,0;QS=3,0;MQSB=0.040184;MQ0F=0 PL:DP:DV 0,21,188:7:0 0,9,88:3:0 0,9,80:3:0 +17 221 . A <*> 0 . DP=14;I16=11,3,0,0,487,17615,0,0,747,42123,0,0,267,6135,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV 0,21,176:7:0 0,9,88:3:0 0,12,101:4:0 +17 222 . A <*> 0 . DP=14;I16=10,3,0,0,465,17367,0,0,687,38523,0,0,242,5578,0,0;QS=3,0;MQSB=0.040184;MQ0F=0 PL:DP:DV 0,21,186:7:0 0,9,85:3:0 0,9,69:3:0 +17 223 . G <*> 0 . DP=13;I16=9,3,0,0,405,14327,0,0,627,34923,0,0,243,5657,0,0;QS=3,0;MQSB=0.0443614;MQ0F=0 PL:DP:DV 0,18,168:6:0 0,6,53:2:0 0,12,81:4:0 +17 224 . G <*> 0 . DP=12;I16=9,3,0,0,379,12759,0,0,627,34923,0,0,270,6370,0,0;QS=3,0;MQSB=0.0443614;MQ0F=0 PL:DP:DV 0,18,168:6:0 0,6,50:2:0 0,12,70:4:0 +17 225 . C <*> 0 . DP=12;I16=8,3,0,0,382,13896,0,0,567,31323,0,0,261,6345,0,0;QS=3,0;MQSB=0.0497871;MQ0F=0 PL:DP:DV 0,18,165:6:0 0,6,48:2:0 0,9,83:3:0 +17 226 . A <*> 0 . DP=13;I16=8,3,0,0,381,13669,0,0,567,31323,0,0,248,5894,0,0;QS=3,0;MQSB=0.0497871;MQ0F=0 PL:DP:DV 0,18,166:6:0 0,6,53:2:0 0,9,84:3:0 +17 227 . C <*> 0 . DP=13;I16=8,4,0,0,406,14306,0,0,596,32164,0,0,267,6253,0,0;QS=3,0;MQSB=0.0249144;MQ0F=0 PL:DP:DV 0,21,190:7:0 0,6,53:2:0 0,9,73:3:0 +17 228 . C <*> 0 . DP=13;I16=9,4,0,0,417,14381,0,0,656,35764,0,0,292,6884,0,0;QS=3,0;MQSB=0.0211283;MQ0F=0 PL:DP:DV 0,21,187:7:0 0,6,45:2:0 0,12,96:4:0 +17 229 . G <*> 0 . DP=13;I16=9,3,0,0,358,11424,0,0,627,34923,0,0,270,6414,0,0;QS=3,0;MQSB=0.0443614;MQ0F=0 PL:DP:DV 0,18,136:6:0 0,6,53:2:0 0,12,70:4:0 +17 230 . C <*> 0 . DP=13;I16=9,4,0,0,461,16861,0,0,656,35764,0,0,292,6920,0,0;QS=3,0;MQSB=0.0211283;MQ0F=0 PL:DP:DV 0,21,186:7:0 0,6,53:2:0 0,12,100:4:0 +17 231 . C <*> 0 . DP=13;I16=7,4,0,0,414,15832,0,0,536,28564,0,0,247,5925,0,0;QS=3,0;MQSB=0.0401934;MQ0F=0 PL:DP:DV 0,18,184:6:0 0,6,53:2:0 0,9,82:3:0 +17 232 . C <*> 0 . DP=14;I16=9,4,0,0,471,17371,0,0,656,35764,0,0,267,6363,0,0;QS=3,0;MQSB=0.0211283;MQ0F=0 PL:DP:DV 0,21,198:7:0 0,6,53:2:0 0,12,101:4:0 +17 233 . A <*> 0 . DP=14;I16=10,4,0,0,496,18142,0,0,716,39364,0,0,292,6984,0,0;QS=3,0;MQSB=0.0183156;MQ0F=0 PL:DP:DV 0,21,192:7:0 0,6,53:2:0 0,15,119:5:0 +17 234 . A <*> 0 . DP=14;I16=10,4,0,0,502,18390,0,0,716,39364,0,0,292,6988,0,0;QS=3,0;MQSB=0.0183156;MQ0F=0 PL:DP:DV 0,21,185:7:0 0,6,53:2:0 0,15,123:5:0 +17 235 . A <*> 0 . DP=14;I16=9,4,0,0,476,17652,0,0,656,35764,0,0,267,6375,0,0;QS=3,0;MQSB=0.0211283;MQ0F=0 PL:DP:DV 0,21,186:7:0 0,6,53:2:0 0,12,111:4:0 +17 236 . G <*> 0 . DP=15;I16=11,4,0,0,501,17481,0,0,776,42964,0,0,290,6924,0,0;QS=3,0;MQSB=0.0161635;MQ0F=0 PL:DP:DV 0,24,206:8:0 0,6,53:2:0 0,15,103:5:0 +17 237 . A <*> 0 . DP=14;I16=9,4,0,0,465,16877,0,0,656,35764,0,0,266,6282,0,0;QS=3,0;MQSB=0.0211283;MQ0F=0 PL:DP:DV 0,24,206:8:0 0,6,53:2:0 0,9,92:3:0 +17 238 . C <*> 0 . DP=14;I16=10,4,0,0,482,17238,0,0,716,39364,0,0,292,6900,0,0;QS=3,0;MQSB=0.0183156;MQ0F=0 PL:DP:DV 0,24,211:8:0 0,6,53:2:0 0,12,82:4:0 +17 239 . A <*> 0 . DP=15;I16=10,5,0,0,525,19155,0,0,776,42964,0,0,292,6852,0,0;QS=3,0;MQSB=0.0497871;MQ0F=0 PL:DP:DV 0,27,223:9:0 0,6,50:2:0 0,12,108:4:0 +17 240 . C <*> 0 . DP=15;I16=10,5,0,0,512,17930,0,0,776,42964,0,0,292,6764,0,0;QS=3,0;MQSB=0.0497871;MQ0F=0 PL:DP:DV 0,27,220:9:0 0,6,53:2:0 0,12,106:4:0 +17 241 . G <*> 0 . DP=15;I16=9,5,0,0,444,14636,0,0,716,39364,0,0,269,6159,0,0;QS=3,0;MQSB=0.0561348;MQ0F=0 PL:DP:DV 0,27,203:9:0 0,6,53:2:0 0,9,59:3:0 +17 242 . C <*> 0 . DP=15;I16=10,5,0,0,555,21177,0,0,776,42964,0,0,292,6624,0,0;QS=3,0;MQSB=0.0497871;MQ0F=0 PL:DP:DV 0,27,242:9:0 0,6,53:2:0 0,12,94:4:0 +17 243 . C <*> 0 . DP=16;I16=9,5,0,0,523,19737,0,0,716,39364,0,0,284,6508,0,0;QS=3,0;MQSB=0.0561348;MQ0F=0 PL:DP:DV 0,24,220:8:0 0,6,53:2:0 0,12,104:4:0 +17 244 . C <*> 0 . DP=16;I16=10,6,0,0,620,24272,0,0,805,43805,0,0,298,6568,0,0;QS=3,0;MQSB=0.0253122;MQ0F=0 PL:DP:DV 0,27,245:9:0 0,9,72:3:0 0,12,106:4:0 +17 245 . A <*> 0 . DP=17;I16=10,7,0,0,649,24843,0,0,865,47405,0,0,299,6553,0,0;QS=3,0;MQSB=0.0509867;MQ0F=0 PL:DP:DV 0,27,236:9:0 0,12,93:4:0 0,12,115:4:0 +17 246 . T <*> 0 . DP=18;I16=10,8,0,0,649,23833,0,0,894,48246,0,0,301,6553,0,0;QS=3,0;MQSB=0.0286491;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,12,94:4:0 0,12,98:4:0 +17 247 . G <*> 0 . DP=18;I16=10,8,0,0,642,23610,0,0,894,48246,0,0,304,6570,0,0;QS=3,0;MQSB=0.0286491;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,12,83:4:0 0,12,103:4:0 +17 248 . T <*> 0 . DP=18;I16=10,8,0,0,636,22944,0,0,894,48246,0,0,307,6605,0,0;QS=3,0;MQSB=0.0286491;MQ0F=0 PL:DP:DV 0,30,234:10:0 0,12,86:4:0 0,12,114:4:0 +17 249 . C <*> 0 . DP=18;I16=10,8,0,0,656,24846,0,0,894,48246,0,0,310,6658,0,0;QS=3,0;MQSB=0.0286491;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,12,79:4:0 0,12,112:4:0 +17 250 . C <*> 0 . DP=19;I16=10,9,0,0,694,26160,0,0,923,49087,0,0,311,6631,0,0;QS=3,0;MQSB=0.0168512;MQ0F=0 PL:DP:DV 0,30,248:10:0 0,12,89:4:0 0,15,142:5:0 +17 251 . A <*> 0 . DP=19;I16=9,9,0,0,688,26506,0,0,863,45487,0,0,313,6627,0,0;QS=3,0;MQSB=0.0208913;MQ0F=0 PL:DP:DV 0,27,233:9:0 0,12,97:4:0 0,15,148:5:0 +17 252 . G <*> 0 . DP=18;I16=8,9,0,0,641,24631,0,0,803,41887,0,0,304,6502,0,0;QS=3,0;MQSB=0.026526;MQ0F=0 PL:DP:DV 0,27,243:9:0 0,12,91:4:0 0,12,121:4:0 +17 253 . C <*> 0 . DP=19;I16=9,10,0,0,705,26921,0,0,892,46328,0,0,319,6687,0,0;QS=3,0;MQSB=0.0132999;MQ0F=0 PL:DP:DV 0,27,247:9:0 0,12,86:4:0 0,18,155:6:0 +17 254 . T <*> 0 . DP=20;I16=10,9,0,0,719,27517,0,0,892,46328,0,0,314,6670,0,0;QS=3,0;MQSB=0.00482795;MQ0F=0 PL:DP:DV 0,30,254:10:0 0,9,72:3:0 0,18,164:6:0 +17 255 . T <*> 0 . DP=21;I16=11,10,0,0,750,27076,0,0,1012,53528,0,0,328,6840,0,0;QS=3,0;MQSB=0.00822975;MQ0F=0 PL:DP:DV 0,33,241:11:0 0,12,95:4:0 0,18,161:6:0 +17 256 . A <*> 0 . DP=22;I16=11,11,0,0,811,30063,0,0,1049,54897,0,0,334,6956,0,0;QS=3,0;MQSB=0.00507916;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,110:5:0 0,18,166:6:0 +17 257 . T <*> 0 . DP=22;I16=11,11,0,0,814,30420,0,0,1049,54897,0,0,341,7101,0,0;QS=3,0;MQSB=0.00507916;MQ0F=0 PL:DP:DV 0,33,247:11:0 0,15,113:5:0 0,18,168:6:0 +17 258 . T <*> 0 . DP=22;I16=11,11,0,0,791,28943,0,0,1049,54897,0,0,347,7225,0,0;QS=3,0;MQSB=0.00507916;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,15,116:5:0 0,18,155:6:0 +17 259 . C <*> 0 . DP=22;I16=11,10,0,0,785,29809,0,0,1020,54056,0,0,332,6936,0,0;QS=3,0;MQSB=0.00822975;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,90:4:0 0,18,170:6:0 +17 260 . T <*> 0 . DP=21;I16=10,11,0,0,829,32899,0,0,989,51297,0,0,360,7556,0,0;QS=3,0;MQSB=0.00660016;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,118:5:0 0,15,156:5:0 +17 261 . G <*> 0 . DP=21;I16=10,11,0,0,735,27379,0,0,989,51297,0,0,367,7761,0,0;QS=3,0;MQSB=0.00660016;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,15,111:5:0 0,15,122:5:0 +17 262 . C <*> 0 . DP=22;I16=10,12,0,0,806,30278,0,0,1049,54897,0,0,373,7941,0,0;QS=3,0;MQSB=0.0122507;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,99:5:0 0,18,164:6:0 +17 263 . C <*> 0 . DP=22;I16=10,12,0,0,799,29717,0,0,1049,54897,0,0,380,8146,0,0;QS=3,0;MQSB=0.0122507;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,98:5:0 0,18,168:6:0 +17 264 . C <*> 0 . DP=22;I16=10,12,0,0,821,31325,0,0,1049,54897,0,0,386,8326,0,0;QS=3,0;MQSB=0.0122507;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,104:5:0 0,18,172:6:0 +17 265 . A <*> 0 . DP=21;I16=9,12,0,0,800,31906,0,0,989,51297,0,0,390,8380,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,114:5:0 0,15,129:5:0 +17 266 . G <*> 0 . DP=21;I16=9,11,0,0,747,28155,0,0,960,50456,0,0,369,7833,0,0;QS=3,0;MQSB=0.0237479;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,12,97:4:0 0,15,138:5:0 +17 267 . T <*> 0 . DP=21;I16=9,11,0,0,739,27465,0,0,960,50456,0,0,373,7935,0,0;QS=3,0;MQSB=0.0237479;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,12,101:4:0 0,15,149:5:0 +17 268 . T <*> 0 . DP=21;I16=9,12,0,0,748,27708,0,0,989,51297,0,0,402,8686,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:DV 0,33,238:11:0 0,15,110:5:0 0,15,156:5:0 +17 269 . C <*> 0 . DP=22;I16=9,12,0,0,764,28632,0,0,989,51297,0,0,381,8211,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,91:4:0 0,15,154:5:0 +17 270 . C <*> 0 . DP=22;I16=9,12,0,0,758,28146,0,0,989,51297,0,0,385,8337,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,96:4:0 0,15,143:5:0 +17 271 . T <*> 0 . DP=22;I16=9,13,0,0,847,32935,0,0,1018,52138,0,0,413,9065,0,0;QS=3,0;MQSB=0.0109431;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,113:5:0 0,15,152:5:0 +17 272 . C <*> 0 . DP=22;I16=9,12,0,0,809,31413,0,0,989,51297,0,0,390,8518,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,96:4:0 0,15,149:5:0 +17 273 . T <*> 0 . DP=22;I16=9,12,0,0,798,30664,0,0,989,51297,0,0,392,8620,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,95:4:0 0,15,161:5:0 +17 274 . C <*> 0 . DP=22;I16=9,12,0,0,763,28177,0,0,989,51297,0,0,394,8746,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,12,101:4:0 0,15,144:5:0 +17 275 . C <*> 0 . DP=20;I16=7,13,0,0,768,29994,0,0,898,44938,0,0,423,9519,0,0;QS=3,0;MQSB=0.0213617;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,114:5:0 0,12,122:4:0 +17 276 . A <*> 0 . DP=20;I16=7,13,0,0,805,32931,0,0,898,44938,0,0,424,9538,0,0;QS=3,0;MQSB=0.0213617;MQ0F=0 PL:DP:DV 0,33,253:11:0 0,15,122:5:0 0,12,124:4:0 +17 277 . G <*> 0 . DP=20;I16=7,13,0,0,764,29732,0,0,898,44938,0,0,425,9579,0,0;QS=3,0;MQSB=0.0213617;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,15,114:5:0 0,12,121:4:0 +17 278 . A <*> 0 . DP=21;I16=6,14,0,0,722,26452,0,0,867,42179,0,0,415,9521,0,0;QS=3,0;MQSB=0.0246228;MQ0F=0 PL:DP:DV 0,30,238:10:0 0,18,123:6:0 0,12,121:4:0 +17 279 . A <*> 0 . DP=22;I16=7,15,0,0,786,28694,0,0,956,46620,0,0,427,9677,0,0;QS=3,0;MQSB=0.0124927;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,123:6:0 0,12,122:4:0 +17 280 . A <*> 0 . DP=22;I16=7,15,0,0,815,31561,0,0,956,46620,0,0,428,9684,0,0;QS=3,0;MQSB=0.0124927;MQ0F=0 PL:DP:DV 0,36,253:12:0 0,18,130:6:0 0,12,129:4:0 +17 281 . G <*> 0 . DP=22;I16=7,15,0,0,820,31416,0,0,956,46620,0,0,428,9662,0,0;QS=3,0;MQSB=0.0124927;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,122:6:0 0,12,123:4:0 +17 282 . G <*> 0 . DP=22;I16=7,15,0,0,806,30420,0,0,956,46620,0,0,427,9609,0,0;QS=3,0;MQSB=0.0124927;MQ0F=0 PL:DP:DV 0,36,253:12:0 0,18,124:6:0 0,12,119:4:0 +17 283 . C <*> 0 . DP=23;I16=7,15,0,0,827,31785,0,0,956,46620,0,0,426,9574,0,0;QS=3,0;MQSB=0.0124927;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,125:6:0 0,12,122:4:0 +17 284 . T <*> 0 . DP=23;I16=7,16,0,0,901,35479,0,0,1016,50220,0,0,431,9593,0,0;QS=3,0;MQSB=0.0194969;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,126:6:0 0,15,144:5:0 +17 285 . G <*> 0 . DP=23;I16=7,16,0,0,860,32856,0,0,1016,50220,0,0,431,9607,0,0;QS=3,0;MQSB=0.0194969;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,119:6:0 0,15,132:5:0 +17 286 . C <*> 0 . DP=24;I16=8,16,0,0,875,32883,0,0,1076,53820,0,0,431,9641,0,0;QS=3,0;MQSB=0.0132999;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,150:7:0 0,15,134:5:0 +17 287 . A <*> 0 . DP=25;I16=9,16,0,0,895,32957,0,0,1136,57420,0,0,432,9696,0,0;QS=3,0;MQSB=0.00934348;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,178:8:0 0,15,133:5:0 +17 288 . T <*> 0 . DP=25;I16=9,16,0,0,931,35011,0,0,1136,57420,0,0,432,9674,0,0;QS=3,0;MQSB=0.00934348;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,184:8:0 0,15,146:5:0 +17 289 . G <*> 0 . DP=25;I16=9,16,0,0,939,36117,0,0,1136,57420,0,0,432,9676,0,0;QS=3,0;MQSB=0.00934348;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,185:8:0 0,15,136:5:0 +17 290 . G <*> 0 . DP=23;I16=8,15,0,0,805,29157,0,0,1047,52979,0,0,433,9651,0,0;QS=3,0;MQSB=0.0177152;MQ0F=0 PL:DP:DV 0,33,240:11:0 0,21,164:7:0 0,15,126:5:0 +17 291 . T <*> 0 . DP=24;I16=8,15,0,0,840,31616,0,0,1047,52979,0,0,421,9479,0,0;QS=3,0;MQSB=0.0177152;MQ0F=0 PL:DP:DV 0,33,244:11:0 0,21,168:7:0 0,15,136:5:0 +17 292 . T <*> 0 . DP=25;I16=9,16,0,0,888,32274,0,0,1167,60179,0,0,436,9668,0,0;QS=3,0;MQSB=0.0197089;MQ0F=0 PL:DP:DV 0,33,253:11:0 0,24,181:8:0 0,18,156:6:0 +17 293 . G <*> 0 . DP=26;I16=10,15,0,0,934,35232,0,0,1167,60179,0,0,424,9488,0,0;QS=3,0;MQSB=0.0095249;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,196:8:0 0,15,145:5:0 +17 294 . A <*> 0 . DP=26;I16=10,16,0,0,931,33937,0,0,1227,63779,0,0,443,9785,0,0;QS=3,0;MQSB=0.0149748;MQ0F=0 PL:DP:DV 0,36,252:12:0 0,24,201:8:0 0,18,161:6:0 +17 295 . C <*> 0 . DP=25;I16=10,14,0,0,897,33973,0,0,1169,62097,0,0,430,9544,0,0;QS=3,0;MQSB=0.0310726;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,180:7:0 0,18,159:6:0 +17 296 . A <*> 0 . DP=25;I16=10,15,0,0,874,31846,0,0,1198,62938,0,0,451,9905,0,0;QS=3,0;MQSB=0.0213617;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,169:8:0 0,18,169:6:0 +17 297 . C <*> 0 . DP=25;I16=9,15,0,0,901,34305,0,0,1138,59338,0,0,445,9901,0,0;QS=3,0;MQSB=0.0273237;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,174:7:0 0,18,161:6:0 +17 298 . A <*> 0 . DP=26;I16=11,15,0,0,936,34652,0,0,1258,66538,0,0,459,10121,0,0;QS=3,0;MQSB=0.017008;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,184:8:0 0,21,191:7:0 +17 299 . C <*> 0 . DP=27;I16=11,15,0,0,971,36863,0,0,1258,66538,0,0,464,10266,0,0;QS=3,0;MQSB=0.017008;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,193:8:0 0,21,189:7:0 +17 300 . A <*> 0 . DP=27;I16=11,15,0,0,1001,39455,0,0,1258,66538,0,0,469,10437,0,0;QS=3,0;MQSB=0.017008;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,204:8:0 0,21,210:7:0 +17 301 . G <*> 0 . DP=25;I16=10,14,0,0,928,36116,0,0,1169,62097,0,0,476,10632,0,0;QS=3,0;MQSB=0.0310726;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,195:7:0 0,21,196:7:0 +17 302 . T <*> 0 . DP=25;I16=10,14,0,0,879,32885,0,0,1169,62097,0,0,483,10849,0,0;QS=3,0;MQSB=0.0310726;MQ0F=0 PL:DP:DV 0,30,231:10:0 0,21,172:7:0 0,21,202:7:0 +17 302 . T TA 0 . INDEL;IDV=7;IMF=1;DP=25;I16=2,4,8,11,214,7674,793,33369,236,10564,993,55133,109,2229,377,8629;QS=0.511212,2.48879;VDB=0.27613;SGB=-4.22417;MQSB=0.0443614;MQ0F=0 PL:DP:DV 167,0,96:11:6 157,0,9:7:6 201,21,0:7:7 +17 303 . G <*> 0 . DP=25;I16=10,15,0,0,976,38516,0,0,1229,65697,0,0,497,11181,0,0;QS=3,0;MQSB=0.0443614;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,197:7:0 0,21,195:7:0 +17 304 . C <*> 0 . DP=27;I16=11,16,0,0,991,37005,0,0,1318,70138,0,0,503,11359,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,206:8:0 0,24,200:8:0 +17 305 . C <*> 0 . DP=27;I16=11,16,0,0,1057,41761,0,0,1318,70138,0,0,510,11508,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,213:8:0 0,24,211:8:0 +17 306 . T <*> 0 . DP=27;I16=11,16,0,0,1033,40253,0,0,1318,70138,0,0,517,11679,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,207:8:0 0,24,217:8:0 +17 307 . G <*> 0 . DP=27;I16=11,15,0,0,984,37886,0,0,1289,69297,0,0,498,11198,0,0;QS=3,0;MQSB=0.174566;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,189:7:0 0,24,203:8:0 +17 308 . C <*> 0 . DP=27;I16=11,16,0,0,892,30810,0,0,1318,70138,0,0,529,11991,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,178:8:0 0,24,185:8:0 +17 309 . G <*> 0 . DP=27;I16=11,16,0,0,951,34599,0,0,1318,70138,0,0,535,12183,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:DV 0,33,243:11:0 0,24,183:8:0 0,24,205:8:0 +17 310 . A <*> 0 . DP=27;I16=11,16,0,0,1001,38063,0,0,1318,70138,0,0,540,12350,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,200:8:0 0,24,217:8:0 +17 311 . C <*> 0 . DP=27;I16=11,16,0,0,1037,40263,0,0,1318,70138,0,0,544,12492,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,215:8:0 0,24,210:8:0 +17 312 . A <*> 0 . DP=26;I16=10,16,0,0,985,38043,0,0,1258,66538,0,0,549,12657,0,0;QS=3,0;MQSB=0.157183;MQ0F=0 PL:DP:DV 0,30,237:10:0 0,24,215:8:0 0,24,218:8:0 +17 313 . A <*> 0 . DP=26;I16=10,16,0,0,983,37969,0,0,1258,66538,0,0,551,12695,0,0;QS=3,0;MQSB=0.157183;MQ0F=0 PL:DP:DV 0,30,235:10:0 0,24,219:8:0 0,24,215:8:0 +17 314 . A <*> 0 . DP=27;I16=10,17,0,0,1050,41798,0,0,1318,70138,0,0,553,12757,0,0;QS=3,0;MQSB=0.195223;MQ0F=0 PL:DP:DV 0,33,250:11:0 0,24,217:8:0 0,24,227:8:0 +17 315 . G <*> 0 . DP=26;I16=10,16,0,0,1025,40941,0,0,1289,69297,0,0,557,12843,0,0;QS=3,0;MQSB=0.252051;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,24,216:8:0 0,24,225:8:0 +17 316 . C <*> 0 . DP=27;I16=10,15,0,0,983,39393,0,0,1252,67928,0,0,535,12277,0,0;QS=3,0;MQSB=0.312403;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,183:7:0 0,24,224:8:0 +17 317 . T <*> 0 . DP=27;I16=10,16,0,0,1028,41392,0,0,1320,72056,0,0,547,12557,0,0;QS=3,0;MQSB=0.377061;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,230:8:0 0,24,206:8:0 +17 318 . G <*> 0 . DP=27;I16=10,17,0,0,1038,40546,0,0,1349,72897,0,0,570,13018,0,0;QS=3,0;MQSB=0.297797;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,27,235:9:0 0,24,208:8:0 +17 319 . A <*> 0 . DP=27;I16=9,17,0,0,994,38654,0,0,1289,69297,0,0,560,12906,0,0;QS=3,0;MQSB=0.346864;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,27,228:9:0 0,21,185:7:0 +17 320 . A <*> 0 . DP=27;I16=10,17,0,0,1022,39418,0,0,1349,72897,0,0,573,13053,0,0;QS=3,0;MQSB=0.297797;MQ0F=0 PL:DP:DV 0,30,247:10:0 0,27,230:9:0 0,24,211:8:0 +17 321 . T <*> 0 . DP=27;I16=10,17,0,0,1026,39772,0,0,1349,72897,0,0,573,13029,0,0;QS=3,0;MQSB=0.297797;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,27,214:9:0 0,24,218:8:0 +17 322 . G <*> 0 . DP=28;I16=10,18,0,0,1091,43151,0,0,1409,76497,0,0,573,13029,0,0;QS=3,0;MQSB=0.343265;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,27,226:9:0 0,27,223:9:0 +17 323 . C <*> 0 . DP=28;I16=9,18,0,0,1067,42619,0,0,1349,72897,0,0,565,12939,0,0;QS=3,0;MQSB=0.394987;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,27,225:9:0 0,24,198:8:0 +17 324 . T <*> 0 . DP=30;I16=12,18,0,0,1145,44221,0,0,1529,83697,0,0,573,13001,0,0;QS=3,0;MQSB=0.264959;MQ0F=0 PL:DP:DV 0,30,253:10:0 0,27,237:9:0 0,33,255:11:0 +17 325 . A <*> 0 . DP=31;I16=13,18,0,0,1132,42058,0,0,1589,87297,0,0,573,12925,0,0;QS=3,0;MQSB=0.235201;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,208:9:0 0,33,255:11:0 +17 326 . T <*> 0 . DP=31;I16=13,18,0,0,1157,44193,0,0,1589,87297,0,0,574,12878,0,0;QS=3,0;MQSB=0.235201;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,216:9:0 0,33,255:11:0 +17 327 . C <*> 0 . DP=31;I16=13,18,0,0,1147,43895,0,0,1589,87297,0,0,575,12861,0,0;QS=3,0;MQSB=0.235201;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,198:9:0 0,33,255:11:0 +17 328 . A <*> 0 . DP=31;I16=13,18,0,0,1167,44531,0,0,1589,87297,0,0,574,12776,0,0;QS=3,0;MQSB=0.235201;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,226:9:0 0,33,255:11:0 +17 329 . T <*> 0 . DP=31;I16=13,18,0,0,1210,47742,0,0,1589,87297,0,0,572,12676,0,0;QS=3,0;MQSB=0.235201;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,237:9:0 0,33,255:11:0 +17 330 . T <*> 0 . DP=31;I16=13,18,0,0,1185,45839,0,0,1589,87297,0,0,568,12510,0,0;QS=3,0;MQSB=0.235201;MQ0F=0 PL:DP:DV 0,33,254:11:0 0,27,231:9:0 0,33,255:11:0 +17 331 . T <*> 0 . DP=32;I16=14,18,0,0,1154,42510,0,0,1649,90897,0,0,563,12327,0,0;QS=3,0;MQSB=0.210122;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,222:9:0 0,36,255:12:0 +17 332 . A <*> 0 . DP=32;I16=14,18,0,0,1156,42666,0,0,1649,90897,0,0,560,12178,0,0;QS=3,0;MQSB=0.210122;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,214:9:0 0,33,255:11:0 +17 333 . A <*> 0 . DP=32;I16=14,18,0,0,1141,41987,0,0,1649,90897,0,0,558,12064,0,0;QS=3,0;MQSB=0.210122;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,223:9:0 0,33,255:11:0 +17 334 . A <*> 0 . DP=32;I16=14,18,0,0,1162,43328,0,0,1649,90897,0,0,556,11986,0,0;QS=3,0;MQSB=0.210122;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,27,221:9:0 0,33,255:11:0 +17 335 . A <*> 0 . DP=32;I16=12,18,0,0,1077,40287,0,0,1529,83697,0,0,552,11934,0,0;QS=3,0;MQSB=0.264959;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,27,219:9:0 0,33,251:11:0 +17 336 . A <*> 0 . DP=32;I16=14,17,0,0,1088,39758,0,0,1612,89528,0,0,536,11574,0,0;QS=3,0;MQSB=0.274662;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,211:8:0 0,36,255:12:0 +17 337 . C <*> 0 . DP=32;I16=13,17,0,0,1115,42381,0,0,1552,85928,0,0,531,11565,0,0;QS=3,0;MQSB=0.301511;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,202:8:0 0,36,255:12:0 +17 338 . T <*> 0 . DP=30;I16=14,16,0,0,1191,47979,0,0,1560,86456,0,0,554,11878,0,0;QS=3,0;MQSB=0.242376;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,226:8:0 0,36,255:12:0 +17 339 . C <*> 0 . DP=31;I16=14,17,0,0,1130,43210,0,0,1589,87297,0,0,554,11874,0,0;QS=3,0;MQSB=0.175471;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,185:8:0 0,36,255:12:0 +17 340 . C <*> 0 . DP=31;I16=14,17,0,0,1196,47044,0,0,1589,87297,0,0,554,11852,0,0;QS=3,0;MQSB=0.175471;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,221:8:0 0,36,255:12:0 +17 341 . T <*> 0 . DP=31;I16=14,17,0,0,1227,48995,0,0,1589,87297,0,0,554,11862,0,0;QS=3,0;MQSB=0.175471;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,216:8:0 0,36,255:12:0 +17 342 . T <*> 0 . DP=31;I16=14,17,0,0,1162,43942,0,0,1589,87297,0,0,554,11904,0,0;QS=3,0;MQSB=0.175471;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,210:8:0 0,36,255:12:0 +17 343 . G <*> 0 . DP=32;I16=14,17,0,0,1150,43702,0,0,1620,90056,0,0,550,11962,0,0;QS=3,0;MQSB=0.283511;MQ0F=0 PL:DP:DV 0,30,249:10:0 0,27,218:9:0 0,36,255:12:0 +17 344 . C <*> 0 . DP=32;I16=14,18,0,0,1181,45169,0,0,1649,90897,0,0,554,12036,0,0;QS=3,0;MQSB=0.210122;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,217:9:0 0,36,255:12:0 +17 345 . T <*> 0 . DP=31;I16=14,17,0,0,1205,47259,0,0,1589,87297,0,0,555,12129,0,0;QS=3,0;MQSB=0.175471;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,221:8:0 0,36,255:12:0 +17 346 . G <*> 0 . DP=31;I16=15,16,0,0,1147,43597,0,0,1620,90056,0,0,557,12255,0,0;QS=3,0;MQSB=0.220358;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,212:8:0 0,36,255:12:0 +17 347 . G <*> 0 . DP=31;I16=14,16,0,0,1119,42227,0,0,1560,86456,0,0,545,12189,0,0;QS=3,0;MQSB=0.242376;MQ0F=0 PL:DP:DV 0,30,251:10:0 0,24,207:8:0 0,36,255:12:0 +17 348 . T <*> 0 . DP=32;I16=15,16,0,0,1145,43007,0,0,1620,90056,0,0,546,12300,0,0;QS=3,0;MQSB=0.220358;MQ0F=0 PL:DP:DV 0,30,243:10:0 0,27,228:9:0 0,36,255:12:0 +17 349 . T <*> 0 . DP=32;I16=16,16,0,0,1194,45350,0,0,1680,93656,0,0,565,12731,0,0;QS=3,0;MQSB=0.201402;MQ0F=0 PL:DP:DV 0,33,246:11:0 0,27,230:9:0 0,36,255:12:0 +17 350 . T <*> 0 . DP=31;I16=16,15,0,0,1142,43072,0,0,1651,92815,0,0,567,12837,0,0;QS=3,0;MQSB=0.286505;MQ0F=0 PL:DP:DV 0,33,249:11:0 0,27,230:9:0 0,33,255:11:0 +17 351 . G <*> 0 . DP=31;I16=16,15,0,0,1146,43750,0,0,1651,92815,0,0,568,12920,0,0;QS=3,0;MQSB=0.286505;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,27,212:9:0 0,33,255:11:0 +17 352 . A <*> 0 . DP=31;I16=16,14,0,0,1150,45520,0,0,1591,89215,0,0,544,12404,0,0;QS=3,0;MQSB=0.242376;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,224:8:0 0,33,255:11:0 +17 353 . G <*> 0 . DP=29;I16=15,14,0,0,1109,43095,0,0,1562,88374,0,0,570,13064,0,0;QS=3,0;MQSB=0.424373;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,27,231:9:0 0,30,255:10:0 +17 354 . A <*> 0 . DP=28;I16=14,14,0,0,1078,42938,0,0,1502,84774,0,0,571,13075,0,0;QS=3,0;MQSB=0.450096;MQ0F=0 PL:DP:DV 0,27,225:9:0 0,27,244:9:0 0,30,255:10:0 +17 355 . G T,<*> 0 . DP=28;I16=14,13,0,1,1001,37907,41,1681,1442,81174,60,3600,547,12487,25,625;QS=2.875,0.125,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.450096;BQB=1;MQ0F=0 PL:DP:DV 14,0,200,38,203,231:9:1 0,27,222,27,222,222:9:0 0,30,255,30,255,255:10:0 +17 356 . G <*> 0 . DP=27;I16=14,13,0,0,993,37481,0,0,1465,83405,0,0,574,13174,0,0;QS=3,0;MQSB=0.580277;MQ0F=0 PL:DP:DV 0,27,228:9:0 0,24,201:8:0 0,30,255:10:0 +17 357 . C <*> 0 . DP=28;I16=14,13,0,0,1021,39471,0,0,1465,83405,0,0,550,12584,0,0;QS=3,0;MQSB=0.580277;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,205:8:0 0,27,251:9:0 +17 358 . A <*> 0 . DP=28;I16=15,13,0,0,1050,40518,0,0,1525,87005,0,0,576,13216,0,0;QS=3,0;MQSB=0.556581;MQ0F=0 PL:DP:DV 0,30,254:10:0 0,24,197:8:0 0,30,255:10:0 +17 359 . G <*> 0 . DP=29;I16=15,13,0,0,1085,42761,0,0,1525,87005,0,0,552,12620,0,0;QS=3,0;MQSB=0.556581;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,21,187:7:0 0,33,255:11:0 +17 360 . A <*> 0 . DP=29;I16=15,14,0,0,1111,43259,0,0,1585,90605,0,0,579,13297,0,0;QS=3,0;MQSB=0.604224;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,24,220:8:0 0,33,255:11:0 +17 361 . A <*> 0 . DP=29;I16=15,14,0,0,1116,43442,0,0,1585,90605,0,0,579,13273,0,0;QS=3,0;MQSB=0.604224;MQ0F=0 PL:DP:DV 0,30,252:10:0 0,24,219:8:0 0,33,255:11:0 +17 362 . A <*> 0 . DP=29;I16=16,13,0,0,1104,42700,0,0,1585,90605,0,0,580,13272,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,218:8:0 0,30,255:10:0 +17 363 . A <*> 0 . DP=29;I16=16,13,0,0,1087,41437,0,0,1585,90605,0,0,581,13245,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,213:8:0 0,30,255:10:0 +17 364 . T <*> 0 . DP=29;I16=16,13,0,0,1032,37960,0,0,1585,90605,0,0,582,13244,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:DV 0,33,250:11:0 0,24,205:8:0 0,30,255:10:0 +17 365 . G <*> 0 . DP=29;I16=16,13,0,0,1105,43079,0,0,1585,90605,0,0,582,13218,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,211:8:0 0,30,255:10:0 +17 366 . A <*> 0 . DP=29;I16=16,13,0,0,1090,41562,0,0,1585,90605,0,0,581,13167,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,211:8:0 0,30,255:10:0 +17 367 . T <*> 0 . DP=29;I16=16,13,0,0,1055,39149,0,0,1585,90605,0,0,579,13093,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,204:8:0 0,30,255:10:0 +17 368 . A <*> 0 . DP=29;I16=16,13,0,0,1054,39632,0,0,1585,90605,0,0,576,12998,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,208:8:0 0,30,255:10:0 +17 369 . T <*> 0 . DP=28;I16=16,11,0,0,1037,40275,0,0,1496,86164,0,0,548,12256,0,0;QS=3,0;MQSB=0.659218;MQ0F=0 PL:DP:DV 0,30,250:10:0 0,21,196:7:0 0,30,255:10:0 +17 370 . C <*> 0 . DP=28;I16=16,12,0,0,1045,40219,0,0,1556,89764,0,0,570,12790,0,0;QS=3,0;MQSB=0.705296;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,201:8:0 0,30,255:10:0 +17 371 . T <*> 0 . DP=29;I16=16,13,0,0,1155,46591,0,0,1616,93364,0,0,567,12725,0,0;QS=3,0;MQSB=0.744925;MQ0F=0 PL:DP:DV 0,30,255:10:0 0,24,227:8:0 0,33,255:11:0 +17 372 . C <*> 0 . DP=30;I16=16,14,0,0,1139,44019,0,0,1676,96964,0,0,564,12636,0,0;QS=3,0;MQSB=0.779025;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,215:8:0 0,33,255:11:0 +17 373 . A <*> 0 . DP=30;I16=16,14,0,0,1142,44118,0,0,1676,96964,0,0,561,12525,0,0;QS=3,0;MQSB=0.779025;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,220:8:0 0,33,255:11:0 +17 374 . T <*> 0 . DP=30;I16=16,14,0,0,1098,41180,0,0,1676,96964,0,0,556,12344,0,0;QS=3,0;MQSB=0.779025;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,221:8:0 0,33,255:11:0 +17 375 . A T,<*> 0 . DP=31;I16=17,13,0,1,1138,43798,14,196,1676,96964,60,3600,547,12177,4,16;QS=2.9661,0.0338983,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.763662;BQB=1;MQ0F=0 PL:DP:DV 0,36,255,36,255,255:12:0 0,24,218,24,218,218:8:0 0,18,255,30,255,255:11:1 +17 376 . G <*> 0 . DP=31;I16=17,14,0,0,1131,42581,0,0,1736,100564,0,0,547,12073,0,0;QS=3,0;MQSB=0.763662;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,24,220:8:0 0,33,255:11:0 +17 377 . T <*> 0 . DP=31;I16=16,14,0,0,1105,41629,0,0,1676,96964,0,0,518,11360,0,0;QS=3,0;MQSB=0.779025;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,24,211:8:0 0,33,255:11:0 +17 378 . T <*> 0 . DP=30;I16=18,12,0,0,1098,41066,0,0,1707,99723,0,0,541,11927,0,0;QS=3,0;MQSB=0.878946;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,186:7:0 0,30,255:10:0 +17 379 . G <*> 0 . DP=29;I16=18,10,0,0,1053,40181,0,0,1618,95282,0,0,534,11848,0,0;QS=3,0;MQSB=0.981777;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,187:7:0 0,30,255:10:0 +17 380 . C <*> 0 . DP=29;I16=18,10,0,0,1087,42743,0,0,1618,95282,0,0,514,11172,0,0;QS=3,0;MQSB=0.981777;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,177:6:0 0,30,255:10:0 +17 381 . T <*> 0 . DP=29;I16=18,11,0,0,1168,47412,0,0,1678,98882,0,0,537,11729,0,0;QS=3,0;MQSB=0.987702;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,21,212:7:0 0,30,255:10:0 +17 382 . T <*> 0 . DP=29;I16=17,11,0,0,1054,40450,0,0,1618,95282,0,0,510,11068,0,0;QS=3,0;MQSB=0.990092;MQ0F=0 PL:DP:DV 0,33,255:11:0 0,21,182:7:0 0,30,255:10:0 +17 383 . T <*> 0 . DP=29;I16=18,10,0,0,1052,39798,0,0,1618,95282,0,0,507,11013,0,0;QS=3,0;MQSB=0.981777;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,18,165:6:0 0,30,255:10:0 +17 384 . A <*> 0 . DP=31;I16=19,11,0,0,1077,39885,0,0,1738,102482,0,0,504,10988,0,0;QS=3,0;MQSB=0.985292;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,176:7:0 0,30,255:10:0 +17 385 . C <*> 0 . DP=31;I16=19,12,0,0,1118,41180,0,0,1798,106082,0,0,527,11569,0,0;QS=3,0;MQSB=0.989977;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,24,186:8:0 0,30,255:10:0 +17 386 . T <*> 0 . DP=30;I16=18,12,0,0,1158,45592,0,0,1738,102482,0,0,526,11556,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,191:7:0 0,30,255:10:0 +17 387 . T <*> 0 . DP=30;I16=18,12,0,0,1105,41821,0,0,1738,102482,0,0,525,11573,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,21,187:7:0 0,30,255:10:0 +17 388 . T <*> 0 . DP=29;I16=17,12,0,0,1089,41577,0,0,1678,98882,0,0,523,11519,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,180:6:0 0,30,255:10:0 +17 389 . G <*> 0 . DP=29;I16=17,12,0,0,1067,40095,0,0,1678,98882,0,0,520,11444,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,171:6:0 0,30,255:10:0 +17 390 . C <*> 0 . DP=29;I16=17,12,0,0,1071,40423,0,0,1678,98882,0,0,517,11399,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,162:6:0 0,30,255:10:0 +17 391 . A <*> 0 . DP=29;I16=18,11,0,0,1091,41603,0,0,1647,96123,0,0,515,11383,0,0;QS=3,0;MQSB=0.995968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,18,163:6:0 0,30,255:10:0 +17 392 . T <*> 0 . DP=29;I16=18,11,0,0,1046,38838,0,0,1647,96123,0,0,515,11395,0,0;QS=3,0;MQSB=0.995968;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,153:5:0 0,33,255:11:0 +17 393 . A <*> 0 . DP=28;I16=17,11,0,0,1014,37582,0,0,1587,92523,0,0,517,11435,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,133:5:0 0,33,255:11:0 +17 394 . T <*> 0 . DP=28;I16=17,11,0,0,1022,38342,0,0,1587,92523,0,0,519,11503,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,141:5:0 0,33,255:11:0 +17 395 . T <*> 0 . DP=28;I16=17,11,0,0,1060,40596,0,0,1587,92523,0,0,521,11599,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,164:5:0 0,33,255:11:0 +17 396 . T <*> 0 . DP=28;I16=17,11,0,0,1032,39228,0,0,1587,92523,0,0,523,11723,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,158:5:0 0,33,255:11:0 +17 397 . T <*> 0 . DP=28;I16=17,11,0,0,1046,39510,0,0,1587,92523,0,0,524,11824,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,36,255:12:0 0,15,149:5:0 0,33,255:11:0 +17 398 . A <*> 0 . DP=28;I16=17,11,0,0,1021,38105,0,0,1587,92523,0,0,524,11850,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,144:5:0 0,30,255:10:0 +17 399 . A <*> 0 . DP=28;I16=17,11,0,0,1015,38469,0,0,1587,92523,0,0,526,11900,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,140:5:0 0,30,255:10:0 +17 400 . A <*> 0 . DP=29;I16=17,12,0,0,1056,39702,0,0,1647,96123,0,0,526,11828,0,0;QS=3,0;MQSB=0.988062;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,159:5:0 0,33,255:11:0 +17 401 . A <*> 0 . DP=29;I16=17,11,0,0,1052,40302,0,0,1587,92523,0,0,501,11113,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,160:5:0 0,30,255:10:0 +17 402 . T <*> 0 . DP=29;I16=17,12,0,0,1082,41232,0,0,1647,96123,0,0,526,11680,0,0;QS=3,0;MQSB=0.988062;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,149:5:0 0,33,255:11:0 +17 403 . T <*> 0 . DP=29;I16=17,12,0,0,1085,40985,0,0,1647,96123,0,0,526,11654,0,0;QS=3,0;MQSB=0.988062;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,148:5:0 0,33,255:11:0 +17 404 . G <*> 0 . DP=29;I16=17,12,0,0,1074,40524,0,0,1647,96123,0,0,525,11609,0,0;QS=3,0;MQSB=0.988062;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,15,131:5:0 0,33,255:11:0 +17 405 . T <*> 0 . DP=27;I16=16,10,0,0,988,37870,0,0,1498,88082,0,0,519,11543,0,0;QS=3,0;MQSB=0.987578;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,9,103:3:0 0,30,255:10:0 +17 406 . G <*> 0 . DP=27;I16=16,11,0,0,976,36752,0,0,1558,91682,0,0,527,11601,0,0;QS=3,0;MQSB=0.992419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,125:4:0 0,30,247:10:0 +17 407 . A <*> 0 . DP=27;I16=16,11,0,0,1007,38355,0,0,1558,91682,0,0,526,11538,0,0;QS=3,0;MQSB=0.992419;MQ0F=0 PL:DP:DV 0,39,255:13:0 0,12,125:4:0 0,30,255:10:0 +17 408 . C <*> 0 . DP=28;I16=16,11,0,0,1006,38136,0,0,1558,91682,0,0,521,11489,0,0;QS=3,0;MQSB=0.992419;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,110:3:0 0,30,244:10:0 +17 409 . T <*> 0 . DP=29;I16=17,12,0,0,1100,42734,0,0,1678,98882,0,0,525,11503,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,131:4:0 0,33,255:11:0 +17 410 . T <*> 0 . DP=29;I16=17,12,0,0,1035,38325,0,0,1678,98882,0,0,524,11432,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,12,125:4:0 0,33,255:11:0 +17 411 . T <*> 0 . DP=29;I16=17,10,0,0,1003,37747,0,0,1558,91682,0,0,496,10716,0,0;QS=3,0;MQSB=0.984677;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,104:3:0 0,30,255:10:0 +17 412 . C T,<*> 0 . DP=30;I16=17,12,1,0,1094,42458,14,196,1678,98882,60,3600,495,10659,25,625;QS=2.97455,0.0254545,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.991968;BQB=1;MQ0F=0 PL:DP:DV 0,30,255,42,255,255:15:1 0,12,124,12,124,124:4:0 0,33,255,33,255,255:11:0 +17 413 . A <*> 0 . DP=31;I16=18,13,0,0,1189,45985,0,0,1798,106082,0,0,520,11258,0,0;QS=3,0;MQSB=0.995005;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,102:3:0 0,33,255:11:0 +17 414 . T <*> 0 . DP=30;I16=18,12,0,0,1151,44355,0,0,1738,102482,0,0,523,11265,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,109:3:0 0,33,255:11:0 +17 415 . G <*> 0 . DP=30;I16=18,12,0,0,1131,43175,0,0,1738,102482,0,0,526,11306,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,110:3:0 0,33,255:11:0 +17 416 . G <*> 0 . DP=30;I16=17,12,0,0,1083,41273,0,0,1678,98882,0,0,514,11156,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,114:3:0 0,30,253:10:0 +17 417 . C <*> 0 . DP=30;I16=18,12,0,0,1114,42244,0,0,1738,102482,0,0,531,11439,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,108:3:0 0,33,255:11:0 +17 418 . A <*> 0 . DP=30;I16=18,12,0,0,1146,44248,0,0,1738,102482,0,0,532,11478,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,111:3:0 0,33,255:11:0 +17 419 . T <*> 0 . DP=30;I16=18,12,0,0,1117,42327,0,0,1738,102482,0,0,532,11498,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,112:3:0 0,33,255:11:0 +17 420 . A <*> 0 . DP=31;I16=18,13,0,0,1117,41011,0,0,1798,106082,0,0,532,11550,0,0;QS=3,0;MQSB=0.995005;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,108:3:0 0,36,255:12:0 +17 421 . A <*> 0 . DP=33;I16=19,14,0,0,1208,45398,0,0,1887,110523,0,0,533,11635,0,0;QS=3,0;MQSB=0.986656;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,113:3:0 0,42,255:14:0 +17 422 . A <*> 0 . DP=33;I16=19,13,0,0,1205,46441,0,0,1827,106923,0,0,510,11082,0,0;QS=3,0;MQSB=0.991023;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,116:3:0 0,39,255:13:0 +17 423 . T <*> 0 . DP=32;I16=19,13,0,0,1202,45416,0,0,1827,106923,0,0,538,11818,0,0;QS=3,0;MQSB=0.991023;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,110:3:0 0,39,255:13:0 +17 424 . A <*> 0 . DP=32;I16=19,13,0,0,1147,41685,0,0,1827,106923,0,0,539,11867,0,0;QS=3,0;MQSB=0.991023;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,106:3:0 0,39,255:13:0 +17 425 . A <*> 0 . DP=29;I16=16,13,0,0,1070,40616,0,0,1647,96123,0,0,542,11900,0,0;QS=3,0;MQSB=0.976248;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,111:3:0 0,33,249:11:0 +17 426 . T <*> 0 . DP=29;I16=16,12,0,0,997,36561,0,0,1587,92523,0,0,519,11287,0,0;QS=3,0;MQSB=0.982906;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,105:3:0 0,30,225:10:0 +17 427 . A <*> 0 . DP=29;I16=16,13,0,0,1024,37266,0,0,1647,96123,0,0,546,11952,0,0;QS=3,0;MQSB=0.976248;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,111:3:0 0,33,242:11:0 +17 428 . C <*> 0 . DP=29;I16=16,13,0,0,1064,39706,0,0,1647,96123,0,0,548,12020,0,0;QS=3,0;MQSB=0.976248;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,111:3:0 0,33,254:11:0 +17 429 . T <*> 0 . DP=30;I16=16,14,0,0,1150,44918,0,0,1707,99723,0,0,549,12067,0,0;QS=3,0;MQSB=0.969373;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,115:3:0 0,33,255:11:0 +17 430 . G <*> 0 . DP=30;I16=16,14,0,0,1113,42443,0,0,1707,99723,0,0,551,12145,0,0;QS=3,0;MQSB=0.969373;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,112:3:0 0,33,246:11:0 +17 431 . G <*> 0 . DP=30;I16=14,14,0,0,1003,36953,0,0,1587,92523,0,0,553,12255,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,101:3:0 0,30,225:10:0 +17 432 . T <*> 0 . DP=28;I16=14,14,0,0,1049,39621,0,0,1587,92523,0,0,556,12346,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,114:3:0 0,30,255:10:0 +17 433 . T <*> 0 . DP=28;I16=14,12,0,0,949,35443,0,0,1467,85323,0,0,509,11217,0,0;QS=3,0;MQSB=0.967472;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,9,112:3:0 0,27,227:9:0 +17 434 . T <*> 0 . DP=29;I16=15,14,0,0,1036,37654,0,0,1647,96123,0,0,561,12567,0,0;QS=3,0;MQSB=0.960561;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,98:3:0 0,30,243:10:0 +17 435 . A <*> 0 . DP=29;I16=15,13,0,0,1024,37970,0,0,1587,92523,0,0,556,12560,0,0;QS=3,0;MQSB=0.968414;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,9,103:3:0 0,30,237:10:0 +17 436 . T <*> 0 . DP=28;I16=14,14,0,0,998,36220,0,0,1587,92523,0,0,564,12654,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,110:3:0 0,27,223:9:0 +17 437 . T <*> 0 . DP=28;I16=13,14,0,0,990,36832,0,0,1558,91682,0,0,549,12435,0,0;QS=3,0;MQSB=0.999706;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,109:3:0 0,24,207:8:0 +17 438 . A <*> 0 . DP=28;I16=14,13,0,0,972,35640,0,0,1527,88923,0,0,540,12082,0,0;QS=3,0;MQSB=0.9585;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,107:3:0 0,24,216:8:0 +17 439 . C <*> 0 . DP=28;I16=14,14,0,0,1055,40273,0,0,1587,92523,0,0,563,12649,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,107:3:0 0,27,224:9:0 +17 440 . A <*> 0 . DP=28;I16=14,14,0,0,1095,43251,0,0,1587,92523,0,0,561,12615,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,115:3:0 0,27,247:9:0 +17 441 . G <*> 0 . DP=29;I16=15,14,0,0,1068,40344,0,0,1647,96123,0,0,559,12605,0,0;QS=3,0;MQSB=0.960561;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,104:3:0 0,27,198:9:0 +17 442 . A <*> 0 . DP=29;I16=15,14,0,0,1091,41507,0,0,1647,96123,0,0,558,12620,0,0;QS=3,0;MQSB=0.960561;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,112:3:0 0,27,233:9:0 +17 443 . A <*> 0 . DP=30;I16=15,14,0,0,1173,49439,0,0,1647,96123,0,0,557,12661,0,0;QS=3,0;MQSB=0.960561;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,129:3:0 0,27,246:9:0 +17 444 . G <*> 0 . DP=29;I16=15,13,0,0,1095,44661,0,0,1587,92523,0,0,557,12727,0,0;QS=3,0;MQSB=0.968414;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,6,91:2:0 0,27,227:9:0 +17 445 . C <*> 0 . DP=30;I16=16,13,0,0,1100,43706,0,0,1647,96123,0,0,557,12817,0,0;QS=3,0;MQSB=0.976248;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,111:3:0 0,27,219:9:0 +17 446 . A <*> 0 . DP=30;I16=16,13,0,0,1107,44265,0,0,1647,96123,0,0,557,12881,0,0;QS=3,0;MQSB=0.976248;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,115:3:0 0,27,232:9:0 +17 447 . C <*> 0 . DP=29;I16=16,12,0,0,1108,45364,0,0,1618,95282,0,0,555,12817,0,0;QS=3,0;MQSB=0.856268;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,114:3:0 0,27,235:9:0 +17 448 . T <*> 0 . DP=29;I16=16,12,0,0,1125,47237,0,0,1618,95282,0,0,553,12773,0,0;QS=3,0;MQSB=0.856268;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,118:3:0 0,27,240:9:0 +17 449 . A <*> 0 . DP=28;I16=15,12,0,0,1091,45981,0,0,1558,91682,0,0,552,12748,0,0;QS=3,0;MQSB=0.84246;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,90:2:0 0,27,245:9:0 +17 450 . G <*> 0 . DP=28;I16=15,12,0,0,1069,44603,0,0,1558,91682,0,0,551,12741,0,0;QS=3,0;MQSB=0.84246;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,91:2:0 0,27,233:9:0 +17 451 . A <*> 0 . DP=28;I16=15,12,0,0,1021,41371,0,0,1558,91682,0,0,550,12752,0,0;QS=3,0;MQSB=0.84246;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,6,93:2:0 0,27,244:9:0 +17 452 . A <*> 0 . DP=31;I16=18,11,0,0,1079,43353,0,0,1678,98882,0,0,530,12420,0,0;QS=3,0;MQSB=0.884952;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,110:3:0 0,24,225:8:0 +17 453 . A <*> 0 . DP=31;I16=17,11,0,0,1037,41069,0,0,1649,98041,0,0,508,11882,0,0;QS=3,0;MQSB=0.967085;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,111:3:0 0,21,221:7:0 +17 454 . A <*> 0 . DP=31;I16=18,12,0,0,1158,47028,0,0,1738,102482,0,0,554,12904,0,0;QS=3,0;MQSB=0.878946;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,113:3:0 0,30,255:10:0 +17 455 . T <*> 0 . DP=32;I16=17,13,0,0,1148,46574,0,0,1715,100251,0,0,550,12864,0,0;QS=3,0;MQSB=0.973855;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,9,113:3:0 0,33,255:11:0 +17 456 . G <*> 0 . DP=32;I16=17,13,0,0,1161,47287,0,0,1746,103010,0,0,534,12296,0,0;QS=3,0;MQSB=0.998031;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,9,116:3:0 0,30,245:10:0 +17 457 . C <*> 0 . DP=33;I16=19,13,0,0,1218,48642,0,0,1835,107451,0,0,563,12967,0,0;QS=3,0;MQSB=0.985204;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,118:3:0 0,33,255:11:0 +17 458 . A <*> 0 . DP=33;I16=19,13,0,0,1226,49034,0,0,1835,107451,0,0,568,12990,0,0;QS=3,0;MQSB=0.985204;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,111:3:0 0,33,255:11:0 +17 459 . T <*> 0 . DP=33;I16=18,13,0,0,1167,46981,0,0,1775,103851,0,0,565,12945,0,0;QS=3,0;MQSB=0.980167;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,6,92:2:0 0,33,255:11:0 +17 460 . G <*> 0 . DP=32;I16=19,12,0,0,1219,50105,0,0,1775,103851,0,0,575,12929,0,0;QS=3,0;MQSB=0.989977;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,116:3:0 0,30,255:10:0 +17 461 . T <*> 0 . DP=32;I16=19,12,0,0,1213,49819,0,0,1775,103851,0,0,577,12845,0,0;QS=3,0;MQSB=0.989977;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,9,115:3:0 0,30,255:10:0 +17 462 . G <*> 0 . DP=32;I16=19,12,0,0,1190,48962,0,0,1775,103851,0,0,580,12792,0,0;QS=3,0;MQSB=0.989977;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,119:4:0 0,30,241:10:0 +17 463 . G <*> 0 . DP=32;I16=19,12,0,0,1114,44214,0,0,1775,103851,0,0,584,12770,0,0;QS=3,0;MQSB=0.989977;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,114:4:0 0,30,221:10:0 +17 464 . A <*> 0 . DP=32;I16=18,11,0,0,1100,43908,0,0,1686,99410,0,0,556,12106,0,0;QS=3,0;MQSB=0.99095;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,12,133:4:0 0,24,213:8:0 +17 465 . C <*> 0 . DP=33;I16=20,11,0,0,1191,48085,0,0,1775,103851,0,0,586,12786,0,0;QS=3,0;MQSB=0.996597;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,140:5:0 0,27,231:9:0 +17 466 . A <*> 0 . DP=34;I16=21,12,0,0,1293,53311,0,0,1895,111051,0,0,597,12897,0,0;QS=3,0;MQSB=0.995633;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,154:5:0 0,30,255:10:0 +17 467 . A <*> 0 . DP=34;I16=21,11,0,0,1256,51450,0,0,1835,107451,0,0,597,12891,0,0;QS=3,0;MQSB=0.998231;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,15,157:5:0 0,27,248:9:0 +17 468 . A <*> 0 . DP=35;I16=22,12,0,0,1274,51268,0,0,1955,114651,0,0,604,12904,0,0;QS=3,0;MQSB=0.997406;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,154:5:0 0,30,251:10:0 +17 469 . A <*> 0 . DP=35;I16=22,12,0,0,1285,52989,0,0,1955,114651,0,0,608,12940,0,0;QS=3,0;MQSB=0.997406;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,146:5:0 0,30,255:10:0 +17 470 . G <*> 0 . DP=35;I16=22,12,0,0,1281,51055,0,0,1955,114651,0,0,612,13016,0,0;QS=3,0;MQSB=0.997406;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,148:5:0 0,30,238:10:0 +17 471 . T <*> 0 . DP=36;I16=22,11,0,0,1239,49021,0,0,1918,113282,0,0,599,12825,0,0;QS=3,0;MQSB=0.915545;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,150:5:0 0,27,232:9:0 +17 472 . T <*> 0 . DP=35;I16=21,12,0,0,1245,48915,0,0,1926,113810,0,0,595,12559,0,0;QS=3,0;MQSB=0.988858;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,153:5:0 0,27,237:9:0 +17 473 . G <*> 0 . DP=35;I16=21,12,0,0,1307,53473,0,0,1926,113810,0,0,599,12651,0,0;QS=3,0;MQSB=0.988858;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,141:5:0 0,27,249:9:0 +17 474 . G <*> 0 . DP=36;I16=22,12,0,0,1284,51708,0,0,1986,117410,0,0,602,12734,0,0;QS=3,0;MQSB=0.986937;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,131:5:0 0,30,255:10:0 +17 475 . G <*> 0 . DP=36;I16=23,12,0,0,1311,51609,0,0,2015,118251,0,0,631,13485,0,0;QS=3,0;MQSB=0.998642;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,141:5:0 0,33,252:11:0 +17 476 . A <*> 0 . DP=36;I16=23,12,0,0,1312,52078,0,0,2015,118251,0,0,634,13606,0,0;QS=3,0;MQSB=0.998642;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,157:5:0 0,33,255:11:0 +17 477 . T <*> 0 . DP=36;I16=23,12,0,0,1318,52668,0,0,2015,118251,0,0,637,13773,0,0;QS=3,0;MQSB=0.998642;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,148:5:0 0,33,255:11:0 +17 478 . T <*> 0 . DP=38;I16=25,12,0,0,1338,51774,0,0,2135,125451,0,0,637,13833,0,0;QS=3,0;MQSB=0.999868;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,18,154:6:0 0,33,255:11:0 +17 479 . A <*> 0 . DP=38;I16=25,12,0,0,1420,57788,0,0,2135,125451,0,0,639,13935,0,0;QS=3,0;MQSB=0.999868;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,18,163:6:0 0,33,255:11:0 +17 480 . G <*> 0 . DP=37;I16=25,11,0,0,1438,60172,0,0,2075,121851,0,0,641,14029,0,0;QS=3,0;MQSB=0.999853;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,165:6:0 0,33,255:11:0 +17 481 . G <*> 0 . DP=37;I16=25,11,0,0,1392,55824,0,0,2075,121851,0,0,642,14112,0,0;QS=3,0;MQSB=0.999853;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,165:6:0 0,33,255:11:0 +17 482 . A <*> 0 . DP=37;I16=24,11,0,0,1352,55134,0,0,2015,118251,0,0,618,13608,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,15,143:5:0 0,33,255:11:0 +17 483 . G <*> 0 . DP=37;I16=24,12,0,0,1417,57747,0,0,2075,121851,0,0,642,14240,0,0;QS=3,0;MQSB=0.999437;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,18,165:6:0 0,33,255:11:0 +17 484 . A <*> 0 . DP=36;I16=24,11,0,0,1340,53992,0,0,2015,118251,0,0,643,14281,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,168:6:0 0,33,255:11:0 +17 485 . G <*> 0 . DP=35;I16=23,12,0,0,1329,51411,0,0,2015,118251,0,0,669,14931,0,0;QS=3,0;MQSB=0.998642;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,160:6:0 0,33,255:11:0 +17 486 . A <*> 0 . DP=34;I16=22,12,0,0,1311,51523,0,0,1955,114651,0,0,671,14989,0,0;QS=3,0;MQSB=0.997406;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,173:6:0 0,33,255:11:0 +17 487 . G <*> 0 . DP=34;I16=22,12,0,0,1306,50760,0,0,1955,114651,0,0,672,15030,0,0;QS=3,0;MQSB=0.997406;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,169:6:0 0,33,255:11:0 +17 488 . A <*> 0 . DP=35;I16=22,12,0,0,1274,48140,0,0,1986,117410,0,0,646,14380,0,0;QS=3,0;MQSB=0.986937;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,177:6:0 0,30,255:10:0 +17 489 . A <*> 0 . DP=35;I16=23,12,0,0,1264,46916,0,0,2015,118251,0,0,671,15015,0,0;QS=3,0;MQSB=0.998642;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,175:6:0 0,33,255:11:0 +17 490 . A <*> 0 . DP=36;I16=24,12,0,0,1332,50280,0,0,2075,121851,0,0,671,15061,0,0;QS=3,0;MQSB=0.999437;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,188:7:0 0,33,255:11:0 +17 491 . T <*> 0 . DP=36;I16=24,12,0,0,1284,46802,0,0,2075,121851,0,0,671,15093,0,0;QS=3,0;MQSB=0.999437;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,178:7:0 0,33,255:11:0 +17 492 . G <*> 0 . DP=35;I16=21,12,0,0,1252,48326,0,0,1926,113810,0,0,621,13859,0,0;QS=3,0;MQSB=0.988858;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,172:6:0 0,30,251:10:0 +17 493 . A <*> 0 . DP=34;I16=22,11,0,0,1273,49481,0,0,1926,113810,0,0,650,14672,0,0;QS=3,0;MQSB=0.981935;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,186:7:0 0,24,240:8:0 +17 494 . A <*> 0 . DP=34;I16=22,12,0,0,1326,52604,0,0,1986,117410,0,0,672,15182,0,0;QS=3,0;MQSB=0.986937;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,196:7:0 0,27,255:9:0 +17 495 . G <*> 0 . DP=34;I16=21,12,0,0,1255,48577,0,0,1926,113810,0,0,647,14611,0,0;QS=3,0;MQSB=0.988858;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,168:6:0 0,27,244:9:0 +17 496 . A <*> 0 . DP=34;I16=22,12,0,0,1250,46926,0,0,1986,117410,0,0,670,15220,0,0;QS=3,0;MQSB=0.986937;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,186:7:0 0,27,249:9:0 +17 497 . C <*> 0 . DP=34;I16=22,12,0,0,1250,47006,0,0,1986,117410,0,0,665,15087,0,0;QS=3,0;MQSB=0.986937;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,164:7:0 0,27,239:9:0 +17 498 . A <*> 0 . DP=34;I16=22,12,0,0,1286,49158,0,0,1986,117410,0,0,661,14987,0,0;QS=3,0;MQSB=0.986937;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,185:7:0 0,27,252:9:0 +17 499 . T <*> 0 . DP=34;I16=23,11,0,0,1224,45284,0,0,1986,117410,0,0,659,14919,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,183:7:0 0,30,255:10:0 +17 500 . A <*> 0 . DP=34;I16=23,11,0,0,1230,45152,0,0,1986,117410,0,0,657,14833,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,179:7:0 0,30,255:10:0 +17 501 . T <*> 0 . DP=33;I16=23,10,0,0,1241,47167,0,0,1926,113810,0,0,656,14778,0,0;QS=3,0;MQSB=0.972757;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,186:7:0 0,27,241:9:0 +17 502 . G <*> 0 . DP=33;I16=23,10,0,0,1215,45829,0,0,1926,113810,0,0,655,14753,0,0;QS=3,0;MQSB=0.972757;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,183:7:0 0,27,235:9:0 +17 503 . T <*> 0 . DP=34;I16=23,11,0,0,1194,43366,0,0,1986,117410,0,0,654,14758,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,177:7:0 0,27,234:9:0 +17 504 . C <*> 0 . DP=34;I16=23,11,0,0,1218,45552,0,0,1986,117410,0,0,651,14643,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,183:7:0 0,27,219:9:0 +17 505 . C <*> 0 . DP=35;I16=23,11,0,0,1207,44321,0,0,1986,117410,0,0,641,14509,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,189:7:0 0,27,221:9:0 +17 506 . A <*> 0 . DP=35;I16=24,11,0,0,1266,46776,0,0,2046,121010,0,0,646,14504,0,0;QS=3,0;MQSB=0.977529;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,188:7:0 0,27,231:9:0 +17 507 . C <*> 0 . DP=35;I16=23,11,0,0,1220,45016,0,0,1986,117410,0,0,635,14401,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,183:7:0 0,27,226:9:0 +17 508 . A <*> 0 . DP=34;I16=24,10,0,0,1204,44542,0,0,1986,117410,0,0,643,14491,0,0;QS=3,0;MQSB=0.970272;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,189:7:0 0,27,220:9:0 +17 509 . C <*> 0 . DP=34;I16=24,10,0,0,1272,48272,0,0,1986,117410,0,0,640,14430,0,0;QS=3,0;MQSB=0.970272;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,186:7:0 0,27,241:9:0 +17 510 . A <*> 0 . DP=34;I16=22,11,0,0,1194,44196,0,0,1926,113810,0,0,613,13773,0,0;QS=3,0;MQSB=0.981935;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,187:7:0 0,24,221:8:0 +17 511 . A <*> 0 . DP=34;I16=23,11,0,0,1222,45562,0,0,1986,117410,0,0,637,14395,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,195:7:0 0,24,233:8:0 +17 512 . A C,<*> 0 . DP=33;I16=22,10,0,1,1121,40793,13,169,1866,110210,60,3600,628,14340,9,81;QS=2.97719,0.022807,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.981935;BQB=1;MQ0F=0 PL:DP:DV 0,39,255,51,255,255:18:1 0,21,183,21,183,183:7:0 0,24,231,24,231,231:8:0 +17 513 . A <*> 0 . DP=32;I16=20,10,0,0,1115,42183,0,0,1746,103010,0,0,598,13624,0,0;QS=3,0;MQSB=0.980594;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,175:6:0 0,24,233:8:0 +17 514 . A T,<*> 0 . DP=32;I16=20,9,0,1,1066,40004,16,256,1686,99410,60,3600,586,13500,11,121;QS=2.97075,0.0292505,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.980594;BQB=1;MQ0F=0 PL:DP:DV 0,31,255,45,255,255:16:1 0,18,171,18,171,171:6:0 0,24,235,24,235,235:8:0 +17 515 . C <*> 0 . DP=32;I16=18,10,0,0,1010,37294,0,0,1626,95810,0,0,561,12915,0,0;QS=3,0;MQSB=0.986018;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,167:6:0 0,24,211:8:0 +17 516 . C <*> 0 . DP=32;I16=21,10,0,0,1100,40570,0,0,1806,106610,0,0,612,13954,0,0;QS=3,0;MQSB=0.977926;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,187:7:0 0,24,215:8:0 +17 517 . T <*> 0 . DP=33;I16=23,10,0,0,1269,49995,0,0,1926,113810,0,0,636,14626,0,0;QS=3,0;MQSB=0.972757;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,201:7:0 0,24,242:8:0 +17 518 . G <*> 0 . DP=34;I16=24,10,0,0,1247,46839,0,0,1986,117410,0,0,636,14696,0,0;QS=3,0;MQSB=0.970272;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,182:7:0 0,24,220:8:0 +17 519 . T <*> 0 . DP=36;I16=25,11,0,0,1283,46693,0,0,2106,124610,0,0,636,14742,0,0;QS=3,0;MQSB=0.975394;MQ0F=0 PL:DP:DV 0,63,255:21:0 0,21,177:7:0 0,24,224:8:0 +17 520 . T <*> 0 . DP=36;I16=24,11,0,0,1238,44894,0,0,2046,121010,0,0,613,14193,0,0;QS=3,0;MQSB=0.977529;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,180:7:0 0,24,223:8:0 +17 521 . C <*> 0 . DP=34;I16=25,9,0,0,1280,49454,0,0,1986,117410,0,0,641,14875,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,191:7:0 0,21,204:7:0 +17 522 . A <*> 0 . DP=32;I16=24,8,0,0,1158,43228,0,0,1897,112969,0,0,646,14960,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,185:7:0 0,15,170:5:0 +17 523 . T G,<*> 0 . DP=32;I16=23,8,1,0,1184,45708,15,225,1837,109369,60,3600,626,14446,25,625;QS=2.9794,0.0206044,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.872525;BQB=1;MQ0F=0 PL:DP:DV 0,44,255,57,255,255:20:1 0,21,191,21,191,191:7:0 0,15,166,15,166,166:5:0 +17 524 . T <*> 0 . DP=32;I16=24,7,0,0,1084,39474,0,0,1837,109369,0,0,629,14483,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,194:7:0 0,12,140:4:0 +17 525 . G <*> 0 . DP=32;I16=24,7,0,0,1181,45669,0,0,1837,109369,0,0,631,14495,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,188:7:0 0,12,129:4:0 +17 526 . C <*> 0 . DP=32;I16=24,7,0,0,1146,43950,0,0,1860,111600,0,0,633,14531,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,21,185:7:0 0,12,131:4:0 +17 527 . A <*> 0 . DP=33;I16=24,8,0,0,1209,46265,0,0,1897,112969,0,0,636,14634,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,194:7:0 0,18,181:6:0 +17 528 . G <*> 0 . DP=33;I16=24,8,0,0,1256,49824,0,0,1897,112969,0,0,634,14484,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV 0,60,255:20:0 0,18,169:6:0 0,18,193:6:0 +17 529 . C <*> 0 . DP=32;I16=24,7,0,0,1148,44362,0,0,1837,109369,0,0,633,14357,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,187:7:0 0,18,184:6:0 +17 530 . T <*> 0 . DP=32;I16=25,7,0,0,1244,49168,0,0,1897,112969,0,0,657,14883,0,0;QS=3,0;MQSB=0.850154;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,196:7:0 0,18,202:6:0 +17 531 . T <*> 0 . DP=32;I16=25,7,0,0,1177,44171,0,0,1897,112969,0,0,654,14714,0,0;QS=3,0;MQSB=0.850154;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,181:7:0 0,18,193:6:0 +17 532 . T <*> 0 . DP=32;I16=24,7,0,0,1153,43543,0,0,1837,109369,0,0,630,14116,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,181:7:0 0,18,192:6:0 +17 533 . C <*> 0 . DP=32;I16=24,7,0,0,1142,43940,0,0,1837,109369,0,0,619,13649,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,178:7:0 0,18,180:6:0 +17 534 . T <*> 0 . DP=31;I16=24,6,0,0,1212,49426,0,0,1777,105769,0,0,615,13479,0,0;QS=3,0;MQSB=0.82403;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,205:7:0 0,18,205:6:0 +17 535 . A <*> 0 . DP=31;I16=24,6,0,0,1080,39870,0,0,1777,105769,0,0,611,13341,0,0;QS=3,0;MQSB=0.82403;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,194:7:0 0,18,189:6:0 +17 536 . C <*> 0 . DP=31;I16=24,7,0,0,1097,40707,0,0,1837,109369,0,0,631,13809,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,184:7:0 0,18,157:6:0 +17 537 . C <*> 0 . DP=31;I16=22,7,0,0,1034,38564,0,0,1717,102169,0,0,587,12861,0,0;QS=3,0;MQSB=0.854582;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,172:7:0 0,18,183:6:0 +17 538 . A <*> 0 . DP=31;I16=24,7,0,0,1138,42478,0,0,1837,109369,0,0,620,13536,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,189:7:0 0,18,181:6:0 +17 539 . T <*> 0 . DP=31;I16=24,7,0,0,1134,42070,0,0,1837,109369,0,0,614,13422,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,178:7:0 0,18,181:6:0 +17 540 . C <*> 0 . DP=31;I16=24,7,0,0,1148,43768,0,0,1837,109369,0,0,608,13340,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,177:7:0 0,18,178:6:0 +17 541 . A <*> 0 . DP=32;I16=24,6,0,0,1083,40483,0,0,1777,105769,0,0,551,11991,0,0;QS=3,0;MQSB=0.82403;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,180:8:0 0,15,150:5:0 +17 542 . C <*> 0 . DP=33;I16=25,6,0,0,1123,41759,0,0,1837,109369,0,0,570,12552,0,0;QS=3,0;MQSB=0.822578;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,172:8:0 0,18,174:6:0 +17 543 . C <*> 0 . DP=34;I16=25,9,0,0,1219,45959,0,0,1986,117410,0,0,601,13245,0,0;QS=3,0;MQSB=0.621145;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,27,194:9:0 0,18,188:6:0 +17 544 . A <*> 0 . DP=33;I16=24,8,0,0,1170,43898,0,0,1866,110210,0,0,570,12506,0,0;QS=3,0;MQSB=0.579578;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,192:8:0 0,18,180:6:0 +17 545 . A <*> 0 . DP=33;I16=25,8,0,0,1174,43602,0,0,1926,113810,0,0,587,12951,0,0;QS=3,0;MQSB=0.576102;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,24,190:8:0 0,18,184:6:0 +17 546 . A <*> 0 . DP=32;I16=24,8,0,0,1126,41444,0,0,1866,110210,0,0,580,12802,0,0;QS=3,0;MQSB=0.579578;MQ0F=0 PL:DP:DV 0,57,255:19:0 0,21,166:7:0 0,18,193:6:0 +17 547 . A <*> 0 . DP=32;I16=24,7,0,0,1129,42381,0,0,1806,106610,0,0,547,12009,0,0;QS=3,0;MQSB=0.525788;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,180:7:0 0,18,195:6:0 +17 548 . A <*> 0 . DP=33;I16=23,9,0,0,1153,42673,0,0,1866,110210,0,0,561,12489,0,0;QS=3,0;MQSB=0.628357;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,181:7:0 0,21,211:7:0 +17 549 . T G,<*> 0 . DP=32;I16=22,8,0,1,1101,40987,20,400,1746,103010,60,3600,530,11716,25,625;QS=2.96748,0.0325203,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.632337;BQB=1;MQ0F=0 PL:DP:DV 0,31,255,48,255,255:17:1 0,21,168,21,168,168:7:0 0,21,208,21,208,208:7:0 +17 550 . T <*> 0 . DP=32;I16=22,9,0,0,1052,37298,0,0,1806,106610,0,0,548,12176,0,0;QS=3,0;MQSB=0.632337;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,150:7:0 0,21,220:7:0 +17 551 . G <*> 0 . DP=31;I16=22,9,0,0,1121,41639,0,0,1806,106610,0,0,541,12045,0,0;QS=3,0;MQSB=0.632337;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,172:7:0 0,21,208:7:0 +17 552 . C <*> 0 . DP=30;I16=21,9,0,0,1093,41365,0,0,1746,103010,0,0,535,11947,0,0;QS=3,0;MQSB=0.636601;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,21,167:7:0 0,21,208:7:0 +17 553 . A <*> 0 . DP=30;I16=20,8,0,0,981,35387,0,0,1626,95810,0,0,485,10831,0,0;QS=3,0;MQSB=0.596163;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,150:6:0 0,21,194:7:0 +17 554 . A <*> 0 . DP=30;I16=19,9,0,0,975,35601,0,0,1626,95810,0,0,488,10906,0,0;QS=3,0;MQSB=0.646113;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,139:5:0 0,24,211:8:0 +17 555 . A <*> 0 . DP=30;I16=20,10,0,0,1024,36526,0,0,1746,103010,0,0,514,11392,0,0;QS=3,0;MQSB=0.679025;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,150:6:0 0,21,211:7:0 +17 556 . C <*> 0 . DP=29;I16=20,9,0,0,1055,39195,0,0,1709,101641,0,0,509,11219,0,0;QS=3,0;MQSB=0.894839;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,158:6:0 0,18,186:6:0 +17 557 . A <*> 0 . DP=27;I16=18,9,0,0,987,36749,0,0,1589,94441,0,0,506,11074,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,157:6:0 0,18,186:6:0 +17 558 . A <*> 0 . DP=27;I16=18,8,0,0,948,35808,0,0,1560,93600,0,0,477,10281,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,143:5:0 0,18,177:6:0 +17 559 . C A,<*> 0 . DP=27;I16=17,8,0,1,908,33726,14,196,1500,90000,29,841,448,9516,25,625;QS=2.92708,0.0729167,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.90038;BQB=1;MQ0F=0 PL:DP:DV 0,42,255,42,255,255:14:0 0,4,116,15,119,123:6:1 0,18,169,18,169,169:6:0 +17 560 . C <*> 0 . DP=28;I16=19,9,0,0,992,36552,0,0,1649,98041,0,0,494,10654,0,0;QS=3,0;MQSB=0.896555;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,160:6:0 0,21,181:7:0 +17 561 . A <*> 0 . DP=28;I16=18,9,0,0,963,35455,0,0,1589,94441,0,0,466,9946,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,158:6:0 0,21,194:7:0 +17 562 . C <*> 0 . DP=28;I16=18,9,0,0,1006,38392,0,0,1589,94441,0,0,463,9893,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,18,153:6:0 0,21,187:7:0 +17 563 . A <*> 0 . DP=27;I16=17,9,0,0,893,32413,0,0,1529,90841,0,0,460,9820,0,0;QS=3,0;MQSB=0.90038;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,15,149:5:0 0,21,179:7:0 +17 564 . C <*> 0 . DP=27;I16=18,9,0,0,859,28747,0,0,1589,94441,0,0,482,10402,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,121:5:0 0,21,182:7:0 +17 565 . G <*> 0 . DP=30;I16=17,9,0,0,818,26928,0,0,1560,93600,0,0,454,9764,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,12,96:4:0 0,21,154:7:0 +17 566 . C <*> 0 . DP=29;I16=15,11,0,0,903,33405,0,0,1529,90841,0,0,424,9084,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,155:5:0 0,18,167:6:0 +17 567 . C <*> 0 . DP=30;I16=15,12,0,0,932,33774,0,0,1589,94441,0,0,462,10178,0,0;QS=3,0;MQSB=0.935229;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,15,155:5:0 0,21,196:7:0 +17 568 . C <*> 0 . DP=29;I16=15,13,0,0,1057,40817,0,0,1649,98041,0,0,482,10438,0,0;QS=3,0;MQSB=0.942064;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,18,183:6:0 0,18,189:6:0 +17 569 . T <*> 0 . DP=30;I16=16,12,0,0,1056,41296,0,0,1649,98041,0,0,493,10655,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,18,190:6:0 0,21,213:7:0 +17 570 . T <*> 0 . DP=30;I16=16,12,0,0,954,34972,0,0,1680,100800,0,0,472,10086,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,15,157:5:0 0,21,195:7:0 +17 571 . C <*> 0 . DP=31;I16=17,12,0,0,1061,40675,0,0,1740,104400,0,0,472,10158,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,15,155:5:0 0,21,193:7:0 +17 572 . A <*> 0 . DP=31;I16=18,12,0,0,1102,42642,0,0,1769,105241,0,0,499,10887,0,0;QS=3,0;MQSB=0.929991;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,203:7:0 0,18,175:6:0 +17 573 . A <*> 0 . DP=31;I16=18,12,0,0,1057,38473,0,0,1769,105241,0,0,501,10975,0,0;QS=3,0;MQSB=0.929991;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,199:7:0 0,18,178:6:0 +17 574 . C A,<*> 0 . DP=31;I16=18,11,0,1,1088,41328,15,225,1740,104400,29,841,478,10422,25,625;QS=2.94071,0.0592885,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.929991;BQB=1;MQ0F=0 PL:DP:DV 0,48,255,48,255,255:16:0 0,9,170,21,173,177:8:1 0,18,173,18,173,173:6:0 +17 575 . T <*> 0 . DP=30;I16=16,10,0,0,1024,41260,0,0,1560,93600,0,0,448,9842,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,42,255:14:0 0,21,209:7:0 0,15,163:5:0 +17 576 . G <*> 0 . DP=30;I16=17,12,0,0,1047,40077,0,0,1709,101641,0,0,507,11087,0,0;QS=3,0;MQSB=0.931617;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,208:8:0 0,15,151:5:0 +17 577 . G <*> 0 . DP=30;I16=16,12,0,0,999,37747,0,0,1649,98041,0,0,489,10755,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV 0,45,255:15:0 0,24,204:8:0 0,15,146:5:0 +17 578 . G <*> 0 . DP=29;I16=16,13,0,0,975,34803,0,0,1709,101641,0,0,520,11286,0,0;QS=3,0;MQSB=0.940317;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,198:8:0 0,15,151:5:0 +17 579 . G <*> 0 . DP=30;I16=15,13,0,0,1028,38752,0,0,1649,98041,0,0,484,10514,0,0;QS=3,0;MQSB=0.942064;MQ0F=0 PL:DP:DV 0,48,255:16:0 0,24,224:8:0 0,12,145:4:0 +17 580 . A C,<*> 0 . DP=30;I16=15,14,1,0,1060,39178,16,256,1709,101641,60,3600,510,11078,17,289;QS=2.97338,0.0266223,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.946202;BQB=1;MQ0F=0 PL:DP:DV 0,34,255,48,255,255:17:1 0,24,221,24,221,221:8:0 0,15,155,15,155,155:5:0 +17 581 . A <*> 0 . DP=31;I16=16,15,0,0,1083,39215,0,0,1829,108841,0,0,530,11384,0,0;QS=3,0;MQSB=0.951229;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,223:8:0 0,15,153:5:0 +17 582 . C <*> 0 . DP=31;I16=15,15,0,0,1080,39870,0,0,1769,105241,0,0,519,11211,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,207:8:0 0,15,151:5:0 +17 583 . T <*> 0 . DP=30;I16=16,14,0,0,1136,43996,0,0,1769,105241,0,0,539,11523,0,0;QS=3,0;MQSB=0.946202;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,238:8:0 0,15,163:5:0 +17 584 . C <*> 0 . DP=31;I16=16,13,0,0,1051,39351,0,0,1709,101641,0,0,499,10619,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,207:7:0 0,15,157:5:0 +17 585 . A <*> 0 . DP=31;I16=17,14,0,0,1096,39866,0,0,1798,106082,0,0,549,11751,0,0;QS=3,0;MQSB=0.998229;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,211:8:0 0,15,157:5:0 +17 586 . T <*> 0 . DP=31;I16=16,14,0,0,1081,39839,0,0,1738,102482,0,0,546,11796,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,24,212:8:0 0,15,156:5:0 +17 587 . C <*> 0 . DP=31;I16=17,13,0,0,1070,39402,0,0,1769,105241,0,0,532,11350,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,201:7:0 0,15,155:5:0 +17 588 . A <*> 0 . DP=31;I16=17,14,0,0,1126,41642,0,0,1798,106082,0,0,562,12140,0,0;QS=3,0;MQSB=0.998229;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,222:8:0 0,15,164:5:0 +17 589 . A <*> 0 . DP=31;I16=17,14,0,0,1157,43973,0,0,1798,106082,0,0,568,12340,0,0;QS=3,0;MQSB=0.998229;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,24,236:8:0 0,15,165:5:0 +17 590 . C <*> 0 . DP=32;I16=16,14,0,0,1094,41302,0,0,1769,105241,0,0,549,11951,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,18,192:6:0 0,18,175:6:0 +17 591 . A <*> 0 . DP=31;I16=16,15,0,0,1165,44163,0,0,1798,106082,0,0,579,12695,0,0;QS=3,0;MQSB=0.999805;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,209:7:0 0,18,188:6:0 +17 592 . A <*> 0 . DP=31;I16=15,15,0,0,1114,42144,0,0,1738,102482,0,0,571,12651,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,215:7:0 0,18,182:6:0 +17 593 . C <*> 0 . DP=31;I16=15,14,0,0,1065,39889,0,0,1709,101641,0,0,550,12132,0,0;QS=3,0;MQSB=0.954405;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,18,191:6:0 0,18,174:6:0 +17 594 . A <*> 0 . DP=33;I16=16,16,0,0,1163,42917,0,0,1858,109682,0,0,572,12672,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,205:7:0 0,24,212:8:0 +17 595 . A <*> 0 . DP=33;I16=17,16,0,0,1130,39996,0,0,1918,113282,0,0,589,12905,0,0;QS=3,0;MQSB=0.999838;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,198:7:0 0,24,213:8:0 +17 596 . A <*> 0 . DP=33;I16=16,16,0,0,1059,37039,0,0,1858,109682,0,0,590,12952,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,169:7:0 0,24,230:8:0 +17 597 . C <*> 0 . DP=33;I16=17,16,0,0,1196,44890,0,0,1918,113282,0,0,592,12990,0,0;QS=3,0;MQSB=0.999838;MQ0F=0 PL:DP:DV 0,54,255:18:0 0,21,204:7:0 0,24,220:8:0 +17 598 . T <*> 0 . DP=33;I16=16,16,0,0,1214,47104,0,0,1858,109682,0,0,593,13013,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,217:7:0 0,24,239:8:0 +17 599 . T <*> 0 . DP=33;I16=16,17,0,0,1183,43669,0,0,1918,113282,0,0,599,13095,0,0;QS=3,0;MQSB=0.999838;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,197:7:0 0,27,247:9:0 +17 600 . G <*> 0 . DP=32;I16=15,17,0,0,1174,44066,0,0,1858,109682,0,0,601,13145,0,0;QS=3,0;MQSB=0.999287;MQ0F=0 PL:DP:DV 0,51,255:17:0 0,21,194:7:0 0,24,232:8:0 diff --git a/test/mpileup/mpileup.2.sam b/test/mpileup/mpileup.2.sam new file mode 100644 index 0000000..337c037 --- /dev/null +++ b/test/mpileup/mpileup.2.sam @@ -0,0 +1,248 @@ +@HD VN:1.0 SO:coordinate +@SQ SN:17 LN:4200 M5:a9a06ca09c111789d92723fbf39820f6 AS:NCBI37 SP:Human +@RG ID:ERR229776 LB:HG00101_I_bc_pelib_1018 SM:HG00101 PI:510 CN:MPIMG PL:ILLUMINA DS:SRP001294 +@PG ID:bwa_index PN:bwa VN:0.5.9-r16 CL:bwa index -a bwtsw $reference_fasta +@PG ID:bwa_aln_fastq PN:bwa PP:bwa_index VN:0.5.9-r16 CL:bwa aln -q 15 -f $sai_file $reference_fasta $fastq_file +@PG ID:bwa_sam PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1530 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) +@PG ID:sam_to_fixed_bam PN:samtools PP:bwa_sam VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file +@PG ID:gatk_target_interval_creator PN:GenomeAnalysisTK PP:sam_to_fixed_bam VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) +@PG ID:bam_realignment_around_known_indels PN:GenomeAnalysisTK PP:gatk_target_interval_creator VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing +@PG ID:bam_count_covariates PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate +@PG ID:bam_recalibrate_quality_scores PN:GenomeAnalysisTK PP:bam_count_covariates VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing +@PG ID:bam_calculate_bq PN:samtools PP:bam_recalibrate_quality_scores VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file +@PG ID:bam_merge PN:picard PP:bam_calculate_bq VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_mark_duplicates PN:picard PP:bam_merge VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.1 PN:picard PP:bam_mark_duplicates VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +ERR229776.1434662 163 17 1 29 63S38M = 189 288 TCTATGACAGGGAGGTCATGTGCAGGCTGGAGAAGGGGACAAGAGGTCCCCAACTTCTTTGCAAAGCTTCTCACCCTGTTCCTGCATAGATAATTGCATGA ?FIFEDHEHF@EJEHCFEGIFHHHJIIKIIKFKMHLILKJJJFGCF@DHILJMHMDEKDGBIJJJGGK@HMKKFJHJIHCIHLHJIIIIKEIJFEGGGDDF MD:Z:38 RG:Z:ERR229776 AM:i:29 NM:i:0 SM:i:29 MQ:i:29 XT:A:M BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@iiffj_gljjeigihgbhgkgihhhhjdhiedfffcce +ERR229776.44080430 163 17 1 29 33S68M = 200 299 AGAAGGGGACAAGAGGTCCCCAACTTCTTTGCAAAGCTTCTCACCCTGTTCCTGCATAGATAATTGCATGACAATTGCCTTGTCCCTGCTGAATGTGCTCT CEHIFEEEIFFKIHIHEBFHGIKGLJLMKKKKJMLBJKCJLJJGIIJFJKJILJMKKJIKKJLKGFJJKBKJKEDAIKHIFHKLHHLHGLFJJH?CCDFDH MD:Z:68 RG:Z:ERR229776 AM:i:29 NM:i:0 SM:i:29 MQ:i:29 XT:A:M BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@lkaijbikiifhhieijihkiljjihjjikjfeiijajijdc`hjghegjkggkgfkeiig^bbcecg +ERR229776.67863896 163 17 1 29 70S31M = 243 336 TCCTTTCTCTATGACAGGGAGGTCATGTGCAGGCTGGAGAAGGGGACAAGAGGTCCCCAACTTCTTTGCAAAGCTTCTCACCCTGTTCCTGCATAGATAAT ?EEIBDFJFJFGHHHHCA7JII@HIIGHFIIJFILIGDAJLICBIGIGMKLFAFJJILIMILIKF@JGGGJJHILEJMICEGFJIHDIHL?G0=>AH@D@GGG@LDAGFDC@GFF?C6BADEA## X0:i:1 X1:i:0 XC:i:100 MD:Z:63T36 RG:Z:ERR229776 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A@@ +ERR229776.5202330 113 17 20 37 101M * 0 0 TGCATAGATAATTGCATGACAATTGCCTTGTCCCTGCTGAATGTGCTCTGGGGTCTCTGGGGTCTCACCCACGACCAACTCCCTGGGCCTGGCACCAGGGA FFFHGKHJIHHHJIIKLKIHGHGIHBCCHEHDDFFFDFIAHI@CE@EHIHBJIKJKLGJKJFIHJFAJGH=:A6JIHFEDGGHGIGH=HFABDA@EIDEEB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 XT:A:U BQ:Z:A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.96861155 99 17 29 60 38M63S = 245 315 AATTGCATGACAATTGCCTTGTCCCTGCTGAATGTGCTCTGGGGTCTCTGGGGTCTCACCCACGACCAACTCCCTGGGCCTGGCACCGGGGAACTTAACAA =BE:CD5=@;3BC5</>E&%()4'5+')=1,)4?C3B5D?:JH'.5>BH5A;*0$;666@FCHCIEIHHIICGDC:GDGFD? MD:Z:8T0G13G0T1T39C34 RG:Z:ERR229776 AM:i:29 NM:i:6 SM:i:29 MQ:i:29 XT:A:M BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.18900347 177 17 69 37 101M * 0 0 GGGGTCTCTGGGGTCTCACCCACGACCAACTCCCTGGGCCTGGCACCAGGGAGCTTAACAAACATCTGTCCAGCGAATACCTGCATCCCTAGAAGTGAAGC DCCBFBGCGFFFHKDJDBGGIC?IIBHHGDLIFJKLJKDGIJJJJLJMMLLNLKLFJIHKBFJJKJJJKLILLBLJIHIKKIKIIJJJIHIHHKEGFGIFC X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 XT:A:U BQ:Z:EBA@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@E +ERR229776.10174020 147 17 73 60 101M = 32 -141 TCTCTGGGGTCTCACCCACGACCAACTCCCTGGGCCTGGCACCAGGGAGCTTAACAAACATCTGTCCAGCGAATACCTGCATCCCTAGAAGTGAAGCCACC CEGFHGHHGJIKDBGGIJAIGDHIFGJFIKJJJKFKKMMLKMLMLMMNMMMJKJKKJHKJLKJKKLKMLBKJIIEKLIKJIKKJKIKJIKDGHHKGDFHBC X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B +ERR229776.54549035 163 17 122 60 101M = 343 321 CTTAACAAACATCTGTCCAGCGAATACCTGCATCCCTAGAAGTGAAGCCACCGCCCAAAGACACGCCCATGTCCAGCTTAACCTGCATCCCTAGAAGTGAA CIFFIEGJJFFHIKIHKJIKJBJLIIJLMKLJJLLLMJMLNMJJLMMJLKKMFGIJDED=?DA?=FIGGBBCE>C;?EJFGFHFCFCHCHDAHEBCHJHGDJDEADFDFI@GJJE>J@A>D=E>D>:7;@:DDCFA= X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:29 NM:i:0 SM:i:29 MQ:i:29 XT:A:U BQ:Z:A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.67863896 83 17 243 29 5S60M1I35M = 1 -336 CACGCCCATGTCCAGCTTATTCTGCCCAGGTCCTCCCCAGAAAGGCTGCATGGTTGACACACAGTAGCCTGCGACAAAGCTGAATGCTATCATTTAAAAAC ######HIJEG0>><CBCJ9BD:1;.;2>AG;7?8&/7.C8D;>9,>;B87E>A:3:BHBE@A:EA X0:i:1 X1:i:0 XC:i:96 MD:Z:24T5T64 RG:Z:ERR229776 AM:i:29 NM:i:3 SM:i:29 MQ:i:29 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.96861155 147 17 245 60 58M1I42M = 29 -315 ATGTCCAGCTTATTCTGCCCAGTTCCTCTCCAGAAAGGCTGCATGGTTGACACACAGTAGCCTGCGACAAAGCTGAATGCTATCATTTAAAAACTCCTTGC CD6;=?GB=-EEDH>IG<=?L@DHBBDCDHHMFCDLGEGG?CJFHGF:EAB0CFHLC>MKGFJI?D@FIILH>IIIIHG;F7A69B=;CA7GEFH/=CB?0 X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR229776 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.70166645 16 17 256 37 47M1I53M * 0 0 ATTCTGCCCAGTTCCTCTCCAGAAAGGCTGCATGGTTGACACACAGTAGCCTGCGACAAAGCTGAATGCTATCATTTAAAAAATCCTTGCTGGTTTGAGAG AIIAMHABJNHLI>COB?CJPHJGPJIHOKC;EJGQGKKI>CFBLGOLDAK6=2G@HLKHH(NHKGPHKN?K>LPB88?A8'&5=FJIJEKCCIM;3MEM< X0:i:1 X1:i:0 MD:Z:81C18 RG:Z:ERR229776 NM:i:2 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.109178428 147 17 278 29 25M1I75M = 49 -328 AAAGGCTGCATGGTTGACACACAGTAGCCTGCGACAAAGCTGAATGCTATCATTTAAAAACTCCTTGCTGGTTTGAGAGGCAGAAAATGATATCTCATAGT ACICF>FF=CFFFEDFG-6CFDMHHLFACFJ5LKJK@MIIKLKJJJCGHKAJLLIJJHJFHGIKLHEJI@HGKFHLJLHHIKJGIHHCIHAGH:DB<=CC: X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR229776 AM:i:29 NM:i:1 SM:i:29 MQ:i:29 XT:A:U BQ:Z:@AD@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.33489754 163 17 286 60 17M1I83M = 565 379 CATGGTTGACACACAGTAGCCTGCGACAAAGCTGAATGCTATCATTTAAAAACTCCTTGCTGGTTTGAGAGGCAGAAAATGATATCTCATAGTTGCTTTAC CGFFDGHFIFFGHHHKHGKJKLJKBKJJMLLLMKLMJLKMKKLIJLKJMNNNKNMMMLLMNLMJKKIKLGGHHIHJHHHGIJHIKINIJIIIIFHHKCCE= X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR229776 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.67002924 99 17 287 60 101M = 567 362 ATGGTTGACAGACAGTGCCTGCGACAAAGCTGAATGCTATCATTTAAAAACTCCTTGCTGGTTTGAGAGGCAGAAAATGATATCTCATAGTTGCTTTACTT 7<937;A%6@AB5AGBCBG4GEE=;?BDHG;9@D@=;BB@GJ@KKKJDB;:@>C?9C??AEAICI6/9@CEDEMFIEDH?C?GC?DD:DB X0:i:1 X1:i:0 MD:Z:10C90 RG:Z:ERR229776 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@FG +ERR229776.39811680 163 17 292 60 11M1I89M = 579 387 TGACACACAGTAGCCTGCGACAAAGCTGAATGCTATCATTTAAAAACTCCTTGCTGGTTTGAGAGGCAGAAAATGATATCTCATAGTTGCTTTACTTTGCA ?CGCFE@E;GHC@EFKB=76DDJDI@BGKCLK8JD6JJAIJBGEBBF?>CCAGCDGEIIFCJGGC;FCEDD@HADHE::=IEGJIGIKIJKDHFKIILIIJJJLLLM?KJKMJJGMJLGCIHLFLHJLKJLMNFIKJIJJJNJKJGCAFFJMHFIGLHIHIJKFFDCC=9DHEBD X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:29 NM:i:0 SM:i:29 MQ:i:29 XT:A:U BQ:Z:A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A +ERR229776.47122623 83 17 316 60 4S97M = 19 -393 AAAGCTGAATGCTATCATTTAAAAACTCCTTGCTGGTTTGAGAGGCATAAAATGATAGCTCATAGTTGCTTTCCTTTGCATATTTTAAAATTGTGACTTTC #####GA7>;IDG@D5LNHDB>8.0DF.FFC::HAA?DD3-BMA;;6+=D=HDD<75'8=<@F@F@<5(G5(%>D>;3*6<'62+7 X0:i:1 X1:i:0 XC:i:97 MD:Z:43G9T14A28 RG:Z:ERR229776 AM:i:37 NM:i:3 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.54549035 83 17 343 60 101M = 122 -321 GCTGGTTTGAGAGGCAGAAAATGATATCTCATAGTTGCTTTACTTTGCATATTTTAAAATTGTGACTTTCATGGCATAAATAATACTGGTTTATTACAGAA CFGFDJKJJOHLIJJHGHHIIILJJJLMLKKJMJMJLMMMIJLLMJKIJJFMLLIJJIHJIIIJHKLKJIGEJJGHGIGGGFCGGGFHEIEBDHBFEIFEC X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A +ERR229776.24914793 99 17 348 60 101M = 613 365 TTTGAGAGGCAGAAAATGATATCTCATAGTTGCTTTACTTTGCATATTTTAAAATTGTGACTTTCATGGCATAAATAATACTGGTTTATTACAGAAGCACT A@EEFE>ED?;EHGIEGDD@FGEEGEGGDEFIJKFIFFKJIHGEIGIKJIELMMJKEBJFHIGEIJJJLKIJDILKJNDKIKKEJKKEIKKGJHJLGCEEI X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D +ERR229776.100438586 99 17 384 60 101M = 443 159 ACTTTGCATATTTTAAAATTGTGACTTTCATGGCATAAATAATACTGGTTTATTACAGAAGCACTAGAAAATGCATGTGGACAAAAGTTGGGATTAGGAGA AACAECGDFCHHIKKFCGHGHLGEIJ=GGJDHJDKMFFHELJHHLBEKKHKIHEHEIJLJNNIGAIIEGEHHGBDCC X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B +ERR229776.100438586 147 17 443 60 101M = 384 -159 AGCACTAGAAAATGCATGTGGACAAAAGTTGGGATTAGGAGAGAGAAATGAAGACATATGTCCACACAAAAACCTGTTCATTGCAGCTTTCTACCATCACC HDBEFGHFHFHIJFCELJLKLFFKIGLEJKAIFEJJMJFMJHJKBJKGBJJMJJFIJFGHGAFEHJHBICCAIEFEGDCF@D@@KHEDFG7CHDBC@;230 X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:C@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.105883979 163 17 445 60 101M = 610 265 CACTAGAAAATGCATGTGGACAAAAGTTGGGATTAGGAGAGAGAAATGAAGACATATGTCCACACAAAAACCTGTTCATTGCAGCTTTCTACCATCACCAA CGEJFGIJJJDHIHHJHFKKIILLLLIJILLKJKJMLKJJKKKLNMKLLMMLKKKKKLKLLKKKKKNNNMJJOKIAKKKFIKLIKMFFIMKGHIHGHDEFD X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@HI +ERR229776.41759951 163 17 452 60 101M = 681 323 AAATGCATGTGGACAAAAGTTGGGATTAGGAGAGAGAAATGAAGACATATGTCCACACAAAAACCTGTTCATTGCAGCTTTCTACCATCACCAAAAATTGC :DEEEG=*BCB.F6FGI==IIF1BDIAIJI,FEH=BFFHD,AECEBFFEF=8DFIGJGF4<++*@KEHDGIJKHHG-?C=DHLIF8GFEIDFGE?BBDBAD X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@IG@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.103175593 163 17 462 60 101M = 681 314 GGACAAAAGTTGGGATTAGGAGAGAGAAATGAAGACATATGTCCACACAAAAACCTGTTCATTGCAGCTTTCTACCATCACCAAAAATTGCAAACAACCAC .6:AFFEEB?<8;:IG?DHH?FI9EIIJJHFGK+:BF8DFAF@DGDJEHHCFECHDC6BE@BEEIBGJMJHKOHDEIEFC=BED6:FEEF=G-9AFE=@BA X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.28425582 99 17 465 60 101M = 698 315 CAAAAGTTGGGATTAGGAGAGAGAAATGAAGACATATGTCCACACAAAAACCTGTTCATTGCAGCTTTCTACCATCACCAAAAATTGCAAACAACCACACG ADD=7HEG2;>@CD7C=@C=@E?CF@?4>BJ>;;9FGH=FGDJHJJJBDC;8=DCEGJGGEHIKHHJEE5@B06C?DHBEHED@# X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.445065 163 17 478 60 101M = 793 406 TAGGAGAGAGAAATGAAGACATATGTCCACACAAAAACCTGTTCATTGCAGCTTTCTACCATCACCAAAAATTGCAAACAACCACACGCCCTTCAACTGGG ?FEDFGHFHHDKKEHEJGJ3HHIIIIKKHIJIJLLLLJILAFJJFJKJ?FGIMKIILJHHFEEFH7IFELLDHKFILFGGKGHJGGGAJIIMHEHIEI7;5 X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.76793083 163 17 490 60 101M = 728 338 ATGAAGACATATGTCCACACAAAAACCTGTTCATTGCAGCTTTCTACCATCACCAAAAATTGCAAACAACCACACGCCCTTCAACTGGGGAACTCATCAAC ?EDHDGHDFHDHHEHGHCHHIKLKJFHJHJKIIIJHIJFHKJJJLJJBFDJKHIJMBIF>AGHGMHIJMIJJJKC=IGDCDGJFHMIE@CKDCMHHFFGB# X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.7941745 163 17 541 60 101M = 806 357 ACCAAAAATTGCAAACAACCACACGCCCTTCAACTGGGGAACTCATCAACAACAAACTTGTGGTTTACCCACACAATGGAAGACCACTTAGCAACAAAAAG ?>?FIJJJHH?GDGCEHIHEG7H<:IKKLJKJLADHCFIGKGMIICBILHJLBHIAGL6C8BA2*;BAAAFE>CH=.C;5AE,5)/<4C=3'=8;;*);10*HHH>?CEC(B9)@@(<:(=>;.G762*6JIB>,6(56--/'GF:7D=486A=BA XC:i:88 MD:Z:17C14C0T17C22A13 RG:Z:ERR229776 AM:i:29 NM:i:5 SM:i:29 MQ:i:29 XT:A:M BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.33489754 83 17 565 60 101M = 286 -379 GCCCTTCAACTGGGGAACTCATCAACAACAAACTTGTGGTTTACCCACACAATGGAAGACCACTTAGCAACAAAAAGGACCAAACTCCTGGTACATGCAAC :?DFIJHHICIHFELHIHJHJIHEHGKIKKB=JMJDJFG.>665CE@HFI>G474>9DF>@?FEA=>=JB:GEE@B>: X0:i:1 X1:i:0 XC:i:83 MD:Z:83 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.89263281 163 17 572 60 101M = 706 234 AACTGGGGAACTCATCAACAACAAACTTGTGGTTTACCCACACAATGGAAGACCACTTAGCAACAAAAAGGACCAAACTCCTGGTACATGCAACTGACAGA CHEJFEEEFIDKIHHKIKIILIILLJLKKJIIIIJJJMMKHJKJNJJLLNMLKMKKMLKKMKNIJMNMMKEKIHIGHGMFHMIGJIGJHHIJIGLGHDGEF X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:AC@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A +ERR229776.40976938 163 17 574 60 101M = 796 322 CTGGGGAACTCATCAACAACAAACTTGTGGTTTACCCACACAATGGAAGACCACTTAGCAACAAAAAGGACCAAACTCCTGGTACATGCAACTGACAGATG ?HDDDEIJFJFHGDHKIHKIIKKGLJIEHIGIIIIIKJHIJJHIJJKLILJMKKMLJKLKNJKMMMNJHLEGHGGGMIHKIGHIGJIHJJHGLHIFHFGDD X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.39811680 83 17 579 60 101M = 292 -387 GAACTCATCAACAACAAACTTGTGGTTTACCCACACAATGGAAGACCACTTAGCAACAAAAAGGACCAAACTCCTGGTACATGCAACTGACAGATGAATCT DAFCCC7EA@GFGFHC:0KCFBBD8MLJEA;?><=:HB?3JIKBBAFBHD?FCE2CG:HEGJE<<@ACDFA8BGFDEB<(GEHGFCA?E@:@9E=F@D?8A X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.96748390 1107 17 579 60 101M = 292 -387 GAACTCATCAACAACAAACTTGTGGTTTACCCACACAATGGAAGACCACTTAGCAACAAAAAGGACCAAACTCCTGGTACATGCAACTGACAGATGAATCT FDGFIEFE@@G>B0CC@0>@FCE=F@MIEGJIDIDE@EGFG?K=BIIJGFBJHE@=9C@HFJE@G:@@?E=D<5>8BH==@@<;@= X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.65100219 99 17 604 60 35M66S = 847 335 TTTACCCACACAATGGAAGACCACTTAGCAACAAAAAGGACCAAACTCCTGGCACATGCAACTGGCAGATGAATCTCAAACGCATTCCTCCGTGTGACAGA 15))2*4?0<4CC>A9<#################################################################################### X0:i:1 X1:i:0 XC:i:35 MD:Z:35 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.105883979 83 17 610 60 101M = 445 -265 CACACAATGGAAGACCACTTAGCAACAAAAAGGACCAAACTCCTGGTACATGCAACTGACAGATGAATCTCAAACGCATTCCTCCGTGTGAAAGAAGCCGG CGFGGEJIHIFMIIGIJHHKLHHEHGJJJIKHHHFIIEBHKLLILIHJJIFLIJILIKHJLKIIJJIHHJHEFB?HIHIIIHGI?EFFGGBBGECIEC:EC X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A +ERR229776.24914793 147 17 613 60 101M = 348 -365 ACAATGGAAGACCACTTAGCAACAAAAAGGACCAAACTCCTGGTACATGCAACTGACAGATGAATCTCAAACGCATTCCTCCGTGTGAAAGAAGCCGGACT @D>GHGHFLFCEHJIHILHDFGDIIEDLGIHEHGC@BGDKJHGJGJJJGJIJKIKJLMICIJJIKEJHJIF>GGILGKJJH=HGHGJDIKFHJFE>DEHE? X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.50340221 99 17 667 60 95M6S = 960 393 GACAGAGGAATCTCAAACGCATTCCTCCGTTTAAAAGAAGCCGGACTCATAGGGCAACACACTATCTGACTGTTTCATGGGAAAGTCTGGAAACGGCAACA =FCDEG*.@56BFHG<58&3)1AJ6(>6'=13=.A3:)2DC@:DA(@;D)B@>B89>BG?;8)@EG@3%;A+>GGKHABEBB####### X0:i:1 X1:i:0 XC:i:95 MD:Z:6T23G1G16C45 RG:Z:ERR229776 AM:i:37 NM:i:4 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.103175593 83 17 681 60 5S96M = 462 -314 ATCTCAAACGCATTCCTCCGTGTGAAAGAAGCCGGACTCACAGGGCAACACACTATCTGACTGTTTCATGGGAAAGTCTGGAAACGGCAACACCATTGAGA ######@E;EBD8+8)1$4:>FAJJKMG?H:*6@<>;:=A@D>9G;0@;06JIG@CA/9F>E??C>F>@AD>DF>A@32>@;')8=;.7F70HHIHIC@EA34IHHE@::*-(<:3H7@CF57>F;B3:07C68;,6A8(<;3563C>;E>= X0:i:1 X1:i:0 XC:i:95 MD:Z:95 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.7320258 99 17 683 60 101M = 985 402 ACGCATTCCTCCGTGTGAAAGAAGCCGGACTCACAGGGCAACACACTATCTGACTGTTTCATGGGAAAGTCTGGAAACGGCAGCACCATTGAGACAGAAAA B+)=AC/=8@4D<6>948=57D;CA@96A;DIB>AG:8>C;;@@EGIA6?FH>EI8CCGJFD=;>20>)1?@8FHC69BI>ABF=C: X0:i:1 X1:i:0 MD:Z:82A18 RG:Z:ERR229776 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A@B@ +ERR229776.28425582 147 17 698 60 18S83M = 465 -315 CAAACGCATTCCGCCGTGTGAAAGAAGCCGGACTCACAGGGCAACCCACTATCTGACTGTTTCATGGGAAAGTCTGGAAACGGCAACACCATTGAGACAGA ###################HD@HDELF6=HHGGIE7DEIGFDBG9%B6FF>:BDF@FF@FJHFEHEEEHHKCG?CHF81I;GC2B>ECCCAEGFKGFED9: X0:i:1 X1:i:0 XC:i:83 MD:Z:27A55 RG:Z:ERR229776 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.89263281 83 17 706 60 101M = 572 -234 GCCGGACTCACAGGGCAACACACTATCTGACTGTTTCATGGGAAAGTCTGGAAACGGCAACACCATTGAGACAGAAAACAGGTGAGTGGTTGCCTGGGGCC >D>FHGHJHGFMHHIIFGIHHEHIKLJJJJKJHLLLKJJJLLKJLGLJJIEIEB@KKFHFCCKJILIDFH>AKIIIGFGJIFFII?GHEIBE>3IJEE;CFHGBJ=8<8IILFEEIIHJGGHDHIF@7CLGH?0094=094%492;>B=CB'%6BBIED@ X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.76793083 83 17 728 60 101M = 490 -338 CTATCTGACTGTTTCATGGGAAAGTCTGGAAACGGCAACACCATTGAGACAGAAAACAGGTGAGTGGTTGCCTGGGGCCAGGGAACTTTCTGGGGTCATAT D=JCDB>CB>EFGBA?E>DGEB?CDBFGCI@BEHCAJGCCK=C@F??EA16>>DCMII@LE@CGDI;@DIIHCGG?@=1= X0:i:1 X1:i:0 MD:Z:75T5G19 RG:Z:ERR229776 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.98656758 163 17 764 60 101M = 1003 339 AACACCATTGAGACAGAAAACAGGTGAGTGGTTGCCTGGGGCCAGGGAACTTTCTGGGGTCATATTCTCTGTGTTGATTCTGGTGGTGGAAACAAGACTGT CHEFDFGHHHHIHEHKJKLLIILKIIKJEGIJJKLLMLLLLMLJMLLLMKNLLMMLLLMFKJKJKJJNJOJJHJJCLIFHMIGHIGJIGHHJGGCGHDJEE X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:AC@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.20493064 99 17 765 60 101M = 1017 352 ACACCATTGAGACAGAAAACAGGTGAGTGGTTGCCTGGGGCCAGGGAACTTTCTGGGGTCATACTCTCTATGTTGATTCTGGTGGTGGAAACAAGACTGTC CDGCDEBFDCCHEFIGIJIFGIHCGFHCEDBIIJIKHHKKKKIKKKJLJLEJKKIILK?HIGIELHLILHIGGJHIIEJLHFHHGDDGJHHGIHGJEKFGE X0:i:1 X1:i:0 MD:Z:63T5G31 RG:Z:ERR229776 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@G +ERR229776.445065 83 17 793 60 9S92M = 478 -406 CAGGTGAGTGGTTGCCTGGGGCCAGGGAACTTTCTGGGGTCATATTCTCTGTGTTGTTTCTGGTGGTGGAAACAAGACTGTCCCAGCCTGGGTGATACAGC ##########CFJE@CGDD@EA;G>>GE8?9?/;AFCHFJJJGBFIDHHIF411A=9>$FC@?FAHDFEC<:8A=GG@;DI=8>E;5:GC4BG:BCE;@A-:>EHJFFHICDGHIG?GEKIHLIIKCHEFB>>=IAIBHHCEE<9BGDA@GBJH8=JD@CGDIJG?FFE X0:i:1 X1:i:0 MD:Z:10T5G84 RG:Z:ERR229776 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.59614566 163 17 820 60 101M = 1133 408 GGGTCATACTCTCTATGTTGATTCTGGTGGTGGAAACAAGACTGTCCCAGCCTGGGTGATACAGCGAGACCCCATCTCTACCAAAAAATTAAAAATTAGCT :;@=AHGFFKFKIHHIFCHHKBHHLIEIIIAFEKLLJJLKLKDHJJHIIKMMLFJJ7=GGIGJLJBLJLEIIGIEHMILFGHJD?JDDEFFIJHGHBFDEF X0:i:1 X1:i:0 MD:Z:8T5G86 RG:Z:ERR229776 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@B@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A +ERR229776.65100219 147 17 847 60 8S93M = 604 -335 GATTCTGTTGGTGGAAACAAGACTGTCCCAGCCTGGGTGATACAGCGAGACCCCATCTCTACCAAAAAATTAAAAATTAGCTGGGCATGGTGGTGCATGCC #########FDGFF:DCFDLEA=0D;BBHLF;6GA-6IJJIH=KI9>G@2019BCAB,F>F=AJBFHA?6?DJJDIEH;HCH>BCA;ACA3;;?G>;C8=. X0:i:1 X1:i:0 XC:i:93 MD:Z:93 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.70908663 16 17 916 37 1S100M * 0 0 TCAGCTGGGCATGGTGGTGCATGCCTGTAGTCCCAGCTATTCACAGTGCTGAGGTCGGAAGATGCCTGAGCCCAGGCGTTCAAGGCTGCAATGAGCTATGA ##J@<:7FM?IMHGLGINGEEJH=>I:MPGD9:NNM?MIQNNMPRJNEMQKLA9D"MLMMM6L2,&PMQJ8?B2I@+:KMN>=2E?AI@HDIFNG8< X0:i:1 X1:i:0 XC:i:100 MD:Z:0T53G9T10A24 RG:Z:ERR229776 NM:i:4 XT:A:U BQ:Z:@@E@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.33718464 147 17 927 60 101M = 717 -310 GGTGGTGCATGCCTGTAGTCCCAGCTATTCACAGTGCTGAGGTGGGAAGATGCTTGAGCCCAGGAGTTCAAGGCTGCAATGAGCTATGATTGCGCCACTGC ;@FCAHGCHGGEHJHIJCJEF?LJIHDED@7CKD;HGJFEIIJGDGBAE5A?IMJLMJGIFLGBIBBJF>LEIJIIF@EIJKICFBHFGKBG?FEFAEGB7 X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.53110448 99 17 947 29 2S31M68S = 1224 373 TACCATCTATTCACAGTGCTGAAATGGGAAGATTCTTGAGCCCAGGAGTTCAATGCTGTAATTACATATGTTATCGACACTGCATTTTGGCCTGGATGAGA B7:11()8::@A?IJIHJJLKIGJEJFHIIGGEFKHHGGFCB0>EEFDG? X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.7320258 147 17 985 60 101M = 683 -402 CCCAGGAGTTCAAGGCTGCAATGAGCTATGATTGCGCCACTGCACTTTGGCCTGGACAACAGAGCAAAACCCTGTCTCTAAAAAAAGAAAAGAAAAGAAAA ?CEIDBKGJJIFLFIIJIIFHCGLCCFFJGDDHJBK?GKGIH=GBCFACECHJHJJIFFJKGJJIJIIFIIJIHGJJJHJIIGBHKHFAGFHHHHKFGCC? X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@IHIG +ERR229776.98656758 83 17 1003 60 101M = 764 -339 CAATGAGCTATGATTGCGCCACTGCACTTTGGCCTGGACAACAGAGCAAAACCCTGTCTCTAAAAAAAGAAAAGAAAAGAAAAACTCACTGGATATGAATG EGGHGLIGIIJIIHJIAIEHHHIIHIHMLJFJIIIHMIJJJHLILIGJJIDLKLIHJCHI>JJJJJJIGIFEJJIIIJIHHFCFGBFAHFABDEBEEEEFC X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.50998015 0 17 1012 37 100M1S * 0 0 ATGATTGCGCCACTGCACTTTGGCCTGGACAACAGAGCAAAACCCTGTCTCTAAAAAAAGAAAAGAAAAGAAAAACTCACTGGATATGAATGATACAGGTT 327C$2FG8CGM@H?563@3I@%2==H;?*@H;E?BF;M>N7FFHGA8GEGHHJIIJIIHJIIFHLCLKIIKKOJNKIKKKJMJMKJLKLKKLLLLLKMJLLLMILKLMKJKJJJJKIJGIKLIIIIKIIIKHHIFKFEJGFJEFC X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.2114306 163 17 1033 60 101M = 1337 404 GGCCTGGACAACAGAGCAAAACCCTGTCTCTAAAAAAAGAAAAGAAAAGAAAAACTCACTGGATATGAATGATACAGGTTGAGGATCCATTATCTGAAATG :;D=IFE9@FED@DHIJGKJKEGELGF>JELIHKKHLLEKLMMKKJLMKGLDLMEGJFHHJFDEKGF@6HJHEKGIHJHDFHFHGCCGDD X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.69497113 83 17 1057 60 45S56M = 717 -395 ATGATTGCGGAACTGGTTTTTGGAGTTTACAACAGAGCAAAAATGTGTCCATAAAAAAAGAAAAGAAAAGAAAAACTCACTGGATATGAATGATACAGGTT ##############################################@J:+B@;91-=/4*GHF9:H<:04+'751:<48A6:0FC4D;A?;<8==CGD>BB X0:i:1 X1:i:0 XC:i:56 MD:Z:4T0C50 RG:Z:ERR229776 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.83355002 99 17 1066 60 101M = 1294 328 AAAAAGAAAAGAAAAGAAAAACTCACTGGATATGAATGATACAGGTTGAGGATCCATTATCTGAAATGCTTGGACCAGATGTTTTGAATTTTGGATTTTTT ABD>CCDHGDHJIJJB?>DCDHIHDID,;5(A:@23?838D87<,<7;-EJH@JHCCC>ED<:BKGFBEB98;F?D8AE11665G6DF:+ X0:i:1 X1:i:0 XC:i:82 MD:Z:82 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.69297552 163 17 1080 60 101M = 1344 364 AGAAAAACTCACTGGATATGAATGATACAGGTTGAGGATCCATTATCTGAAATGCTTGGACCAGATGTTTTGAATTTTGGATTTTTTCATATTTTGTAATC ?CHADJJDJHFGKEHIHDAGHLCIIIIIJJIEHIKJILJLLJJKJJLMJLMMJJLMKJJKILJKGDKHKJLKGLJKKIKIKHHKKLFIJIFIFJEGECFEC X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.44123845 163 17 1082 60 101M = 1361 379 AAAAACTCACTGGATATGAATGATACAGGTTGAGGATCCATTATCTGAAATGCTTGGACCAGATGTTTTGAATTTTGGATTTTTTCATATTTTGTAATCTT CHHIIEKGGFIHHJHIHFJLIJKIIJJJIJJIJJIKILKJJKJKLMJLMMJJMNIHJLILKKCGIKJKKJLLKJKIKKMFLLLBILJJKKKKKHFGHFGCD X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:EIGGD@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@EI +ERR229776.59579091 99 17 1088 60 101M = 1308 320 TCACTGGATATGAATGATACAGGTTGAGGATCCATTATCTGAAATGCTTGGACCAGATGTTTTGAATTTTGGATTTTTTCATATTTTGTAATCTTTGCAGT CBGCIE@GEBBGHIGFIGCFGIHFGCGHGFEKIFIJIHJLHIKIIHJLJKFLHLJLKIKJKKKKLKIIKKJILJKKKKKJKKKJFKKHKIHIHMEEGGGFF X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B +ERR229776.33511586 163 17 1116 60 101M = 1421 405 GATCCATTATCTGAAATGCTTGGACCAGATGTTTTGAATTTTGGATTTTTTCATATTTTGTAATCTTTGCAGTATATTTACCAGTTCAGCATCCCTAACTC CGFFEGHHGHFKHJKKIFKLJJKKIJILKIKJJIJIKLJKLLKLLKKLKKLMKKKKLLLLJJLKMNLLLLKMKKKKKLJIJEJIKLLLHLJKIJHJGDAIC X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.65575982 147 17 1120 60 101M = 818 -402 CATTATCTGAAATGCTTGGACCAGATGTTTTGAATTTTGGATTTTTTCATATTTTGTAATCTTTGCAGTATATTTACCAGTTCAGCATCCCTAACTCAAAA ACGFDCGIIFDGJJJNLHIH@=NKKKJLNJKKKKMLMIEFKLIGINLJJJHLMHJKJKJEFLLJJHMJIIJILKGIIILHLJGIFFCDEEGGCFHIFGFC? X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@IKIG +ERR229776.45364215 163 17 1122 60 101M = 1385 363 TTATCTGAAATGCTTGGACCAGATGTTTTGAATTTTGGATTTTTTCATATTTTGTAATCTTTGCAGTATATTTACCAGTTCAGCATCCCTAACTCAAAAAT CEFFFKHIJIFHIKIHHJHKIJJIIIJIIIKLJJKJILKHKLKLLJJJJJLLLLJJMJMLKKHLJKKJJKKKKKKJKILIKLHLKLLKINKHGKHHFEEDE X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@G +ERR229776.59614566 83 17 1133 60 5S96M = 820 -408 GAAATGCTTGGACCAGATGTTTTGAATTTTGGATTTTTTCATATTTTGTAATCTTTGCAGTATATTTACCAGTTCAGCATCTCTAACTCAAAAATTCAAAA ######GJJ@=GEHICDIFNGCFDA@MMLE=AJLEEIIGA5@D>GLICGBAC>EJCD3IA@6F9KH:;BHF=JH@H=@?B=69FF@>GGG7BEEEGCEGGGFACEF:CCB@DCHHEGJHEJCLFCBJEGIJJH;CGCIJIBELGJJC8F X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:DDC@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A +ERR229776.10204227 99 17 1173 60 101M = 1423 350 TTGTAATCTGTGCAGTATATTTACCAGTTCAGCATCCCTAACTCAAAAATTCAAAAATCTGAAATCCCAAACGCGCCAATAAGCATTCCCTTTGAGCGTCA :5=DC<<=G++:?>GAF=88=BDFFA9-.8:D9@FJHJEJAB?=D@BCKKFJKJLMCCB:FH68B8@3<;FJHH@D?B?@CBDJFJJC,6,?9BJ?:8:ICICIIMK?IDJDDIKIIJ@;@@B?HC### X0:i:1 X1:i:0 XC:i:99 MD:Z:99 RG:Z:ERR229776 AM:i:25 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A@@@ +ERR229776.53110448 147 17 1224 29 4S97M = 947 -373 AATTAAAAAATCTGAAATCCCAAACGCGCCAATAAGCATTCCCTTTGAGCGTCATGTCGGTGCTTGGAATGTTTGGGGTTTTGGATTTACAGCTTTGGGAC #####C@CEE6,JC+6.I7CD5:22;1A&=FBFABADLKKG>DGG?5H:ACCEJJH>:=C8662CC;E?E6);,4-20,)=(B44316)92:4@DAHH8HF;@CA>?>9ADE8/<8BF:F57C3:9><;C?A2= X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.69297552 83 17 1344 60 101M = 1080 -364 CTGATTTTAAAAAAGTTTGGGGGGATTCCCCTAAGCCCGCCACCCGGAGACAGCGGATTTCCTTAGTTACTTACTATGCTCCTTGGCCATTTCTCTAGGTA CGFFIJIIFFHFFLEDBCFFDAAC;F9:1EG>CKLIJDLJ@IHIGKIHIKGIFH98I<7.GB6GEBHBHFFF=BAFH8>>B1 X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.31884178 163 17 1349 29 101M = 1660 348 TTTAAAAAAGTTTGGGGGGATTCCCCTAAGCCCGCCACCCGGAGACAGCGGATTTCCTTAGTTACTTACTATGCTCCTTGGCCATTTCTCTAGGTATTGGT &BH>7GDDFGHF@=CDKC@DKHGEILJEJHC&88F=GFIHDIIHC?.@DEA6 X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:29 NM:i:0 SM:i:29 MQ:i:29 XT:A:U BQ:Z:@AD@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.44123845 83 17 1361 60 101M = 1082 -379 TGGGGGGATTCCCCTAAGCCCGCCACCCGGAGACAGCGGATTTCCTTAGTTACTTACTATGCTCCTTGGCCATTTCTCTAGGTATTGGTATATTGTGTCTG FECDEEFDCGGGGIIFIIBF@FB@=BHAJKMDJJLKCLMIMMLKLMJKHJBFIJI=JGHFJGJGIKIJIDCBDHJFHHEJIFFGJEHFGGBBGE?DCFEFC X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.72241554 163 17 1365 60 101M = 1597 332 GGGATTCCCCTAAGCCCGCCACCCGGAGACAGCGGATTTCCTTAGTTACTTACTATGCTCCTTGGCCATTTCTCTAGGTATTGGTATATTGTGTCTGCTGT CBBHFHGFEGIHKJJJJ"1BHGJJ@GIJKHJJIAIKJKJLMKJHKJJIIMIIGMIJGILIFKCFDGFHGDDKMHLJCFBAFHIGHIIIILIJIHHLGFIBE X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:HGD@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.45364215 83 17 1385 60 101M = 1122 -363 ACCCGGAGACAGCGGATTTCCTTAGTTACTTACTATGCTCCTTGGCCATTTCTCTAGGTATTGGTATATTGTGTCTGCTGTGAACTGTCCTTGGCCTGTTT />=?GHLHICII?EIHMJLEHGHGFDDDGI=EJGG?GIKLJDIIKEIFKKDBKHIJHIHGHH>HIHF?JH@EDGJGGGCEG;DGGEGFFGE@CA:CECDBA X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A +ERR229776.26840652 99 17 1389 60 101M = 1635 346 GGAGACAGCGGATTTCCTTAGTTACTTACTATGCTCCTTGGCCATTTCTCTAGGTATTGGTATATTGTGTCTGCTGTGAACTGTCCTTGGCCTGTTTGGTG <?ABECCIJJLJ@BCFAHIJILLCGJIDDGDGBEDJ@+>EGFKHN@CMKIJ;1+C?C3@ICF=D@I?GBA<IEGHIHJCDHCDJIB@DFHKJJHKHJLEIIILJFHJJJJMKJJGK@JJFKJJLJFKJJKCHLJKKIHIIKLIJHIEA&GHHFIKEHJF:KDEFG? X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.33511586 83 17 1421 60 101M = 1116 -405 GCTCCTTGGCCATTTCTCTAGGTATTGGTATATTGTGTCTGCTGTGAACTGTCCTTGGCCTGTTTGGTGACGGGTGAGGAGCAGGGACAGAAGGGTCCTGC CCE@GGIHF=D:EHKEJHHKHFHDBHJEGDEFKIFHEDJGH@IEDIIIKIEKIJKFJHCIDILKIJHCFE7IIHHHJJGIH;BFA:E>F(15.)1'0%1?EB1E(/;3?HHJ5)=CE>5=/8:D89;;EDF=%:A6=#################################### X0:i:1 X1:i:0 XC:i:66 MD:Z:60T5 RG:Z:ERR229776 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.10204227 147 17 1423 60 101M = 1173 -350 TCCTTGGCCATTTCTCTAGGTATTGGTATATTGTGTCTGCTGTGAACTGTCCTTGGCCTGTTTGGTGACGGGTGAGGAGCAGGGACAGAAGGGTCCTGCGT D>AGEGF@8EBKKDH?DLDB=@HKGCHFGJGKIHDGFFEDHHFHC7KKJKDHMFIHGCJELLFKHIJI>IHCIILC>LGIKHGEHEJGIKEGFIEGFE:C? X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.66536220 99 17 1466 60 101M = 1680 314 GAACTGTCCTGGGCCTGTTTGGTGACGGGTGAGGAGCAGGGACAGAAGGGTCCTGCGTGCCCTGCCTTCACAAGCCCCTGGAAGGAAAGTTGTTTTGGGAT A@DBIE==>>/<>>HHEDD@GGCDHH8BG>?JE:DIJHGDBD=AIJLJHH0G(>;D;=DHF:G?BEHFEEDHICFGD=6A;>EB=?KJD7>E13?EA2=CD X0:i:1 X1:i:0 MD:Z:10T90 RG:Z:ERR229776 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.46562341 99 17 1476 60 101M = 1781 398 TGGCCTGTTTGGTGACGGGTGAGGAGCAGGGACAGAAGGGTCCTGCGTGCCCTGCCTTCACAAGCCCCTGGAAGGAAAGTTGTTTTGGGATCTCTGCACCC AABECG5A8>E@C;FD>3F=;=CCEDGCHFC7C6D?@?F@B>CK=EC?ACB?=;6@93E*A??B690<<935:FB>1--?@KC@HE7= X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.93812627 163 17 1518 60 82M19S = 1829 411 CTGCGTGCCCTGCCTTCACAAGCCCCTGGAAGGAAAGTTGTTTTGGGATCTCTGCACCCTCAGCCTGGACAACTTGTGCCCATCTGGTGACCCCTCACTCA CHFF=GHHFHIHIGKJKGIIKJKKKKLICKMJCKMLMJJJJKKKJLJLD@C?:<>@=DIH,GCCEEBA+6DGC0BCBADCH#################### X0:i:1 X1:i:0 XC:i:82 MD:Z:82 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.9004658 163 17 1520 60 99M2S = 1782 362 GCGTGCCCTGCCTTCACAAGCCCCTGGAAGGAAAGTTGTTTTGGGATCTCTGCACCCTCAGCCTGGACAACTTGTGCCCATCTGGTGACCCCTCACTCAGC 7E:EEGFEHFBCKFHBCFAFHHHGKIFJHJEGLKHIJHEJKHJJGFFFMJMGHJHIILLKFCEKDEGCEBCIHHHIIIHCHILH2@?CFHFFIDHBJF### X0:i:1 X1:i:0 XC:i:99 MD:Z:99 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.78137857 147 17 1530 60 101M = 1262 -368 CCTTCACAAGCCCCTGGAAGGAAAGTTGTTTTGGGATCTCTGCACCCTCAGCCTGGACAACTTGTGCCCATCTGGTGACCCCTCACTCAGCCACCAGACTT ABFCBF?CIG>:EHJIIFMHICFMDKIFGLJGIIJJLKLKJKKHJLKLJLMJMJLJJLJJKBJHIHLEHIJJJLIHIEKIKKJFHKJIKHEGGEHKFGCH? X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C@ +ERR229776.95913538 83 17 1542 60 66S35M = 1208 -368 TTGCTTTTGTGCTACATGTGCAGGGTTGTGTACTCAAGTAGTCGGATTTCCCTCTTTTCCAAAGCTCCTCGAAGGAAAGTTGTTTTGGGATCTCTGCTCCC #######################################################################>D:3EHI?IE5(9=?>*B7/&<-1%')&(+ X0:i:1 X1:i:0 XC:i:35 MD:Z:3G27A3 RG:Z:ERR229776 AM:i:25 NM:i:2 SM:i:25 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.72241554 83 17 1597 60 101M = 1365 -332 CCATCTGGTGCCCCCTCACTCAGCCACCAGACTTCCACGACAGGCTCCAGCCTCGGCACCTTCAGCCATGGACAGTTCCGCCAGCGTTGCCCTCTGTTCTG AFD@BGEBA;"GGBFAB:E>CG@=@@DEKA5AGF?>;:GACD@BADBEGG:CGAEED>G?IDHKJJJFFJIGIKHJII?HGFIH?BIDGCB>FEBCGEEFA X0:i:1 X1:i:0 MD:Z:10A90 RG:Z:ERR229776 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:CH@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.50673799 83 17 1617 29 13S87M1S = 1336 -367 GTGACCACTCCCTCAGCCACCAGACTTCCACGACAGGCTCCAGCCTCGGCACCATAAGCCCTGAACAATTCCGCCAGCGTTGCCATCTGTTCTGATGTTTG ##############IG@:;@@:B>DC7#8E;D5,*=:#57*824:?GE@<;,9GAAC53?@EGGHLHLHFHIHKHIHHGHHFFHGFJFB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@AA +ERR229776.26840652 147 17 1635 60 101M = 1389 -346 GACAGGCTCCAGCCTCGGCACCTTCAGCCATGGACAGTTCCGCCAGCGTTGCCCTCTGTTCTGCTGTTTTCTCTACCAGAAGTGCCCTTCCCTCCTCACCT @==<5E?8GIMJCDHAIIHIE?EJ?MHED?IHFAGDBEAB.5:>9A6>BB@)=?EI################################ X0:i:1 X1:i:0 XC:i:70 MD:Z:70 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.76819541 99 17 1638 60 101M = 1879 341 AGGCTCCAGCCTCGGCACCTTCAGCCATGGACAGTTCCGCCAGCGTTGCCCTCTGTTCTGCTGTTTTCTCTACCAGAAGTGCCCTTCCCTCCTCACCTGAC A@BDIEAE>'?CB@FHJ:JJDD==8EIHJ?KJLFCGGKHCEED:BHIKDHAF>FDAIGGGICHIHIEHLI4AFIFDJAHD X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@F +ERR229776.37392358 99 17 1651 60 49M52S = 1874 323 GGCACCTTCAACCATGGACAGTGCCGCCAGCGCTGCCCTCTGTTCTGCTGCTTTCTCTACCAGAAGTGCCCTGCCCTCCTCACCAAACCACTCTGGGGAAA +(23:@9=7:':++?;8E:@E?('1*?EFE=2&225(6;=+5::AAEH##################################################### X0:i:1 X1:i:0 XC:i:49 MD:Z:10G11T9T16 RG:Z:ERR229776 AM:i:25 NM:i:3 SM:i:25 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.5880975 147 17 1658 60 37S64M = 1423 -298 CACCAGACTTCCACGACAGGCTCCAGCCTCGGCACCTTCAGCCATGGACAGTTCCGCCAGCGTTGCCCTCTGTTCTGCTGTTTTCTCTACCAGAAGTGCCC ######################################CKEAGEDB@?CKCKLF+35/*:4+&+&/1410')677 XC:i:38 MD:Z:8A5C18T4 RG:Z:ERR229776 AM:i:29 NM:i:3 SM:i:29 MQ:i:29 XT:A:M BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.25705936 99 17 1670 60 101M = 1870 298 AGTTCCGCCAGCGTTGCCCTCTTTTCTGCTGTTTTCTCTACCAGAAGTGCCCTTCCCTCCTCACCTGACCACTCTGGGGAAATCCCTCAGCACCCTCCCTG 9FD8A?B>;GHIFJC<7@CEJHEBE=HKI@?AHD;A#@/<>C*5DFGFIJCDAK?A>G@ X0:i:1 X1:i:0 MD:Z:22G78 RG:Z:ERR229776 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.66536220 147 17 1680 60 101M = 1466 -314 GCGTTGCCCTCTGTTCTGCTGTTTTCTCTACCAGAAGTGCCCTTCCCTCCTCACCTGACCACTCTGGGGAAATCCCTCAGCACCCTCCCTGAGCATACCCT E=DEHEFGIJIJHIKIJIIJGFHKKGJHIHEGKGJKDGJGGKMJILKKIIHC@JKIIFFF@JKKJLLLKJKIKLKJKJLIHCKFIJJJHHFKGHHGDD@CB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.46562341 147 17 1781 60 7S94M = 1476 -398 ATACCCTACTCTGGCACAAGCCCACCCTGCAAAGCCCCTGAGGCCCGCCCTGTGGCGTCTCTCCCTCCCTTGCTGTCAGGACAGTGGTCCTGGCCACCGGG ########CGDDFFIHD@FC8?DICDBFEHDF4684;EA>;8EHE<<5CCC=;7@:0<>@:D=CA>7:49*:CIHIFCH>?GJ;86/9<;??F=1+A?3(=64;:?::,CABHJIHIFIGLFEHGKBECBGA@FAB>>C<;ADCDECA>:AEIEH>BHHIHFIJH@HHEEFFEFDHGJFGCGECGEGG@BCE<@C?F@C X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.59635540 99 17 1831 60 101M = 2100 369 TCTCTCCCTCCCTTGCTGTCAGGACAGTGGTCCTGGCCACCGGGGCTCACGGAGCCGCCCTGTGCCGTGTACCTCTGAGCCCTCTGCACAGTGCCTTCTGC =BH99E@;GBAECD9;GFFJJDAFGF=;?DHKFH:4CEJ>C9B@@B?GBD?1083@;AKHLGIGHGFLHMIIAE:?HHIHKDGJF> X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.80549332 99 17 1853 60 69M32S = 2041 288 GACAGTGGTCCTGGCCTCCGGGGCTCACGGAGCCGCCCTGTGCCGTGTACCTCTGAGCCCTCTGCACAGTCCCTTCTGCTTGCCTGTGGCTTTGAGAAGAA 9>;>5D<6:5;?EAD@@98.8??<+:4@HG:)./=:GE.)337?BJ:GB=;=E################################# X0:i:1 X1:i:0 XC:i:69 MD:Z:16A52 RG:Z:ERR229776 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.25705936 147 17 1870 60 2S99M = 1670 -298 CTCCGGGGCTCACGGAGCCGCCCTGTGCCGTGTACCTCTGAGCCCTCTGCACAGTGCCTTCTGCTTGCCTGTGGCTTTGAGAAGAAACCCCTTCTGGTTAT ###8DBED@G@G69@8GCMCIFGFKG;>E9=BH>B@0FCEHKIJHEF7@JJHIFIJJLIDGC5D=AAEHCI??EIHD?BGEF:G@CH=AFKEC;E4 X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.11564716 99 17 1934 60 101M = 2208 374 GCCTGTGGCTTTGAGAAGAAACCCCTTCTGGTTATACATAAGACAGCCAGAGAAGGGAGTTGCCCAGGGTGGCACAGCACGTTGCTGCCAGTTACTGCCAT +9DH=77>D@7G;?E=F:@CJG=BFIFFH:7HDCF?A@CHEIBDH?IHILFHKKDIE;9;9AEECHFC82:AHJIIGHIF@GFCIL>IFJIGE X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@G +ERR229776.65159506 163 17 1948 60 101M = 2208 360 GAAGAAACCCCTTCTGGTTATACATAAGACAGCCAGAGAAGGGAGTTGCCCAGGGTGGCACAGCACGTTGCTGCCAGTTACTGCCATTTTCACAGGCATGA 4DEEEFCDEEAKDFJCDCDGHHGHHHBJDGFFIKJJIBJLCIJHKGCICIJIKCCDFBJKIJKKJHBIJHIMHIHKGIHDGLEIHJIHFFGJGGGAEEE@F X0:i:1 X1:i:0 MD:Z:93G7 RG:Z:ERR229776 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@H +ERR229776.44568317 99 17 2014 60 101M = 2277 363 GTTGCTGCCAGTTACTGCCATTTTCACGGGCATGAAATGGAGATAACAACAGGAGCGACCGCACAGGCTGCTGAGCGCGTCACACGCAGCCATCGCGCAGC ADBEEIBEC@@EGAFEFIH@GEEHGGG?GDBHGBJKJGFGHFIFFKGJLFEKJGCFABGG?BGABEDEGFDKGIGH@H@FDGFIG97AE@FBH>@D599*/FHEC@47?560FEGBHEA:AB6-E1+A8?*+:LGHHCC2>+>2>HEACGFH:A/A>: X0:i:1 X1:i:0 MD:Z:0G100 RG:Z:ERR229776 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:gPC@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.71965236 163 17 2100 60 101M = 2416 416 CAGCCATCGCGCAGCTCAGGGATATTACGTGTAACTCGACATGTCAGCGATTGTCACAGGCACTGCTACTCCTGGGGTTTTCCATCAAACCCTCAAGAGCT BGEFEGHG=H>HHJIKKHKKKKIIIJIIAIGIIKHMKAJJKKJJJKMMCLKLJKKJGGKGJJHLDIKHEKGHKHEBC8C4DHHHJEDCKHEEDBHDDHCFB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.59635540 147 17 2100 60 101M = 1831 -369 CAGCCATCGCGCAGCTCAGGGATATTACGTGTAACTCGACATGTCAGCGATTGTCACAGGCACTGCTACTCCTGGGGTTTTCCATCAAACCCTCAAGAGCT AF>>BHJ>G:IHLFDEILDDDCFFFFH>FHGHDELL=JKGKKJLCNJ;EILIGLJJHMHF;5JIFJIFE@CFIKHGFILKJF>EEGHG@KI;JHIIGEIFHG>GCBBJEIBJFCGJBGBFLJHMGHNJHAD111AJECDFHMDDHFIHHD;HDCLF9:@CJDCBB6>DCDHD X0:i:1 X1:i:0 MD:Z:0A100 RG:Z:ERR229776 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@CB +ERR229776.8956867 163 17 2145 60 98M3S = 2440 388 AGCGATTGTCACAGGCACTGCTACTCCTGGGGTTTTCCATCAAACCCTCAAGAGCTGGGCCTGGGGTCAACTTCCGGCCTGGGGAAACTGGGGCAAGTATC :CE=FGDF9>@BGGD?F@<;GECFLIHKI>FA.>?@>GIIDILLH?EJFFCDKKJIDFGF=CGFFDCC>HEDHLHECBFGBB#### X0:i:1 X1:i:0 XC:i:98 MD:Z:98 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.11564716 147 17 2208 60 101M = 1934 -374 GGGTCAACTTCCAGCCTGGGGAAACTGGGGCAAGTATCACCAGAGATGAGCTTTATAAAAATAATGGTGCTAGCTGGGCATGGTGGCTTGCACCTGTAATC BDDHFEGHHJGIMJDCLIKKICHLJKMJLLILNJJJECBJJLMMLJKLMLJLMJKKLLKKKJJKJKIIHLJLLLJJJJGHIHHGJKIHHG?CDHGEFGFG? X0:i:1 X1:i:0 MD:Z:12G88 RG:Z:ERR229776 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:GIF@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A +ERR229776.65159506 83 17 2208 60 101M = 1948 -360 GGGTCAACTTCCAGCCTGGGGAAACTGGGGCAAGTATCACCAGAGATGAGCTTTATAAAAATAATGGTGCTAGCTGGGCATGGTGGCTTGCACCTGTAATC B@?IBDAGFFGIMIGIJHHF@JKKDKJGJJFJMGEECBBBFLIFKIIKLKGLJIIIJIIJHIIHCJE>GGBDFDFDBE>GB<1=CEEEDA X0:i:1 X1:i:0 MD:Z:12G88 RG:Z:ERR229776 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:GEA@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C +ERR229776.13912851 0 17 2209 37 101M * 0 0 GGTCAACTTCCGGCCTGGGGAAACTGGGGGAAGTATCACCAGAGATGAGCTTTATAAAAATAATGGTGCTAGCTGGGCATGGTGGCTTGCACCTGTAATCC G>@GOFHFC>LGG@95'JIG;MCHHI"7::5G:FDH3K8LDFFP?IEPG@IHMPOPJBPRH@B?@=,:DLOFDEJQDDC<>?KL=CB0=INF5AEF>:5@GIKIIJJLIHJOKGFGMMKLLJMHEJ?JLLKJIMMMIJFKAJLMJKKHJEBJJJLHLLIHEF=JEKGEHHFHEFGFFC X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.68077221 99 17 2314 60 39M62S = 2563 345 TCTTTGGGAGGCCGAGCTAGGAGAATCGTTTGATTCCAGCAGTTTGAGACCAGCCTGCCCGATACGGCAAATCCCAGTCTCTATAAAAAATACAAAAAAAA +-;)5(221::@C/3&8F842:3'0.:",+0D;)8+?B############################################################### X0:i:1 X1:i:0 XC:i:39 MD:Z:0A22G9G5 RG:Z:ERR229776 AM:i:25 NM:i:3 SM:i:25 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.60999876 83 17 2359 60 18S83M = 2117 -324 GTTTGAGCCCAGCAGTTTGAGACCAGCCTGGCCAATACGGCAAAACCCAGTCTCTACAAAAAATACAAAAAACAACTAGCCAGGCGTGGTGGTGCACTCCT ###################KF=>C=:%+.80/;CB@30C3==;.G::HD<*(G>4-34(;8<6/209>(364-/+);7B X0:i:1 X1:i:0 XC:i:83 MD:Z:79A3 RG:Z:ERR229776 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.71965236 83 17 2416 60 101M = 2100 -416 CTAGCCAGGCGTGGTGGTGCACACCTGTAGTCCCAGCTACTCAGGAGGCTGAGGGGGAAGGACTGCTTGAGCCCAGGAGTTTGAGGCTGCTGTGAGCTGTG @FJEBBBDE:EGEDEFGI@=0<=DHIHJNHIC=@HID@=HHDJEIIKJEI>JDIGEDB@D@CFHHCIJIKHIJGJJEHJHGGFGGB@EEFECEDDA X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.2016000 163 17 2435 60 101M = 2660 325 CACACCTGTAGTCCCAGCTACTCAGGAGGCTGAGGGGGAAGGACTGCTTGAGCCCAGGAGTTTGAGGCTGCTGTTAGCTGTGATCGCATCACTGCATTCCA ?GEFDFKHHGGIIJJHGFKHILLIJKGHEILHKHILLFKMMCKJMJLMJBLBHFIJGHLJEGIBJCDHKGFKHIDIIHL?BCHII=FEFEJGMHHHGGFDF X0:i:1 X1:i:0 MD:Z:74G26 RG:Z:ERR229776 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A +ERR229776.101388755 99 17 2440 60 101M = 2722 382 CTGTAGTCCCAGCTACTCAGGAGGCTGAGGGGGAAGGACTGCTTGAGCCCAGGAGTTTGAGGCTGCTGTGAGCTGTGATCGCATCACTGCATTCCAGCCCG :A=DCC7@?;FBBGB::?8*=@5>D7>HBF3B?C?F8@EG?BBCC:??EIE?FH8=:B/<=>HFGGG?CA8G@2AJHKHCF>D@H<=CDC; X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.8956867 83 17 2440 60 7S94M = 2145 -388 TGCCCACCTGTAGTCCCAGCTACTCAGGAGGCTGAGGGGGAAGGACTGCTTGAGCCCAGGAGTTTGAGGCTGCTGTGAGCTGTGATCGCATCACTGCATTC ########JC@GC<>6&):BC;<;AA=81?E=DEDD@9 X0:i:1 X1:i:0 XC:i:94 MD:Z:94 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.13231970 99 17 2448 29 6S29M66S = 2649 301 ATAATGCCAGCTACTCATGGGGCTGAGGGTTAAGGACGGGTTGAGCCCAGGAGTTTGAAGCTGCTGTGAGCTCTGATGGCATCACTGCATTCCAGCCCGGG +2;*;'0.135EB7H?<.2.=&01>3>B<######################################################################## XC:i:35 MD:Z:11G1A9G0G4 RG:Z:ERR229776 AM:i:29 NM:i:4 SM:i:29 MQ:i:29 XT:A:M BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.25467915 99 17 2456 60 101M = 2477 121 TCAGGAGGCTGAGGGGGAAGGACTGCTTGAGCCCAGGAGTTTGAGGCTGCTGTGAGCTGTGATCGCATCACTGCATTCCAGCCCGGTGACAGAGTGAGTCA BBFCAGBCDE@HHHFGIIIHIIEIEHJI:@CHIJFKKIGGGIJJJKKLFHDJHHHFGHDGFFHEKJJJJJLLMJILLIKIIJIFDBG/GIIFHJGHHJEFEC X0:i:1 X1:i:0 MD:Z:87A13 RG:Z:ERR229776 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B +ERR229776.3800945 83 17 2522 60 9S92M = 2266 -347 TGTGATCGCCTCCCTGCATTCCAGCCCGGTGACAGAGTGAGTCACTGTCTCAAAAAAGAAAGGAAGAAATAAAGAAAACAAATAAAAATAATAGTGCAGAC ##########G@=CCE>,EA<<>4:JCGBE<==KJGIGID@G<7?IEB@'C@91F>9EB<(5=G?>JGCB@7AGE;41D;95BF<:DCH6FC:29('/EBFDE=AAEEGGIEGJ';FIIKGHEJHEJKKKHILHIIFFJHLKJJLKGKJILMKALILCJJDLIKHMKKKJKJINJKKKLJKJMGHAIMIHJHIE>FA X0:i:1 X1:i:0 MD:Z:18A82 RG:Z:ERR229776 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:GLI@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C +ERR229776.13231970 147 17 2649 29 101M = 2448 -301 ATCAACCGCTAGATACGTCCCTCCCTTTCTTCTGGGGCACAGGTCACACTCTCTTCCAGGTCTAGGATGCAGCTGAGGGGTGCCCCTCTTACCATCTAATC 6F=CA96B-EEGF620>,*965AB>=EF?,DCKEEE>?HBE@B@0 X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:29 NM:i:0 SM:i:29 MQ:i:29 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.44981660 163 17 2656 60 101M = 2879 323 GCTAGATACGTCCCTCCCTTTCTTCTGGGGCACAGGTCACACTCTCTTCCAGGTCTAGGATGCAGCTGAGGGGTGCCCCTCTTACCATCTAATCTGTGCCC ?EIFFHHGF?FIIJJIJHLJJKLJIIIICBIIIJHIEHEHJIMLJJMBIIJHFJJKJ>?FGJKKMMNIJHKHBACEGIHFIMFIGIJHILFEHHGDFEFED X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ACD +ERR229776.2016000 83 17 2660 60 101M = 2435 -325 GATACGTCCCTCCCTTTCTTCTGGGGCACAGGTCACACTCTCTTCCAGGTCTAGGATGCAGCTGAGGGGTGCCCCTCTTACCATCTAATCTGTGCCCTTAT B?C4=DGB8HJCCIKFGBDHCFGGGHHHGLHDGFCEBBKBIJIHEDLKHKDJLKJHGDEGA;GJKJF@GHBBB>C>EDDGF;CCEBGAIGB@DA:=:CE9A X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C +ERR229776.74190027 163 17 2668 60 98M3S = 3014 419 CCTCCCTTTCTTCTGGGGCACAGGTCACACTCTCTTCCAGGTCTAGGATGCAGCTGAGGGGTGCCCCTCTTACCATCTAATCTGTGCCCTTATTTCCTCTG CEIFEFKHHHIIIHIJHJIIHIJKFHGGHGKKLKLJMMJKLFJLJKLKJJMKMMMLLKMMJFKJIIINGKJJIHJHJMIFKIMHJIJIIMFIIJJEF#### X0:i:1 X1:i:0 XC:i:98 MD:Z:98 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:EG@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.31785601 117 17 2710 0 35M66S = 2710 0 AGGCAGAGACCTGATCACGGATCACAGCCGCCTCAAACTGTTGGGCTCAACCTGAACGTCCCTTCTTGCCTGGTTAGTTGTTCGGACTACAGGTGTGCGCC ########################################################################################B37.<90;7((/= XC:i:35 RG:Z:ERR229776 +ERR229776.31785601 185 17 2710 37 101M = 2710 0 CTAGGATGCAGCTGAGGGGTGCCCCTCTTAGCATCTAATCTGTGCCCTTATTTCCTCTGCGTTAGTGAGGAAGAGGCCCCTGGTCCATGAAGGGGCCTTTC >AF>>=C6,*58,CCC(%(,9FB?E8$4EIA7/,E@HCC@G?.IGHGC7FB7FF-C=@E;DGGABBEGEEDEG: X0:i:1 X1:i:0 MD:Z:30C29T40 RG:Z:ERR229776 AM:i:0 NM:i:2 SM:i:37 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.101388755 147 17 2722 60 101M = 2440 -382 TGAGGGGTGCCCCTCTTACCATCTAATCTGTGCCCTTATTTCCTCTGCTTTAGTGAGGAAGAGGCCCCTGGTCCATGAAGGGGCCTTTCAGAGACGGGGAC 5BFEDECIICCBFJHKFIEEHEHIIIJHJEIIBA>KHGKHKDFCFBGBALIGIIIILJCIGLIIIF=HIKHKIIIIKJKHHHC8BKJE=JAIF??FDEFG? X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A +ERR229776.3777343 99 17 2723 60 101M = 2891 268 GAGGGGTGCCCCTCTTACCATCTAATCTGTGCCCTTATTTCCTCTGCTTTAGTGAGGAAGAGGCCCCTGGTCCATGAAGGGGCCTTTCAGAGACGGGGACC A@BCCA28?A:FJFG>FFH>FIHHKGIKG8@HIGIIFHIJFJKKKCGLJJ8FDFHCEEJFE;>@GHHK@DCCGGIGIIGD?@FFIHHIJHJA:?:>E@C9: X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.16418187 163 17 2727 60 94M7S = 2953 318 GGTGCCCCTCTTACCATCTAATCTGTGCCCTTATTTCCTCTGCTTTAGTGAGGAAGAGGCCCCTGGTCCATGAAGGGGCCTTTCAGAGACGGGGACCCCTG ?=GEEFFEJFEDGCHG?B8@JHIKG7CFHHGAFIJJKEFJ9=FABI@C1;HIFHEIHIJJ>EILKBE9EA>CLGH7:C(<0EDGJDKFKH:@@######## X0:i:1 X1:i:0 XC:i:94 MD:Z:94 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:B@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.60225376 163 17 2734 60 88M13S = 3018 318 CTCTTACCATCTAATCTGTGCCCTTATTTCCTCTGCTTTAGCGAGGAAGAGGCCCCTGGTCCATGAAGGGGCCTTTCAGAGACGGGGACCCCTGAGGAGGC 4ED@3FDDF@=JG?HEB=2;ACGD>EFJ>>8@FLA5C>BGF*08=&*4<*7%<))4@?:HAFJ>?HD>EJD:@,<:=CC############## X0:i:1 X1:i:0 XC:i:88 MD:Z:41T46 RG:Z:ERR229776 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.107194084 163 17 2742 60 101M = 3015 367 ATCTAATCTGTGCCCTTATTTCCTCTGCTTTAGTGAGGAAGAGGCCCCTGGTCCATGAAGGGGCCTTTCAGAGACGGGGACCCCTGAGGAGCCCCGAGCAG ?EFJFJHGJGFHIJJKIHIJJKHLILIKMJKHJFJGJJKMMLKJAIILMLMJMMIJLLMIGFDFJMKJKKJMKJG>GGC;@GFFB=E@CC@FEHH@2;AD@ X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.107791703 99 17 2817 29 1S34M66S = 3127 380 GGGGTACCCCTGATGAGCCCCGTGAAACAGCCGTCGATTCTCACCCGGGGGGTCGGAAACAGGTGGGGAGGTCTGGGGAGGGGCGTGGCGCAGCTGCGGGG ##################################################################################################### XC:i:35 MD:Z:3G8G8A1C1G8 RG:Z:ERR229776 AM:i:29 NM:i:5 SM:i:29 MQ:i:29 XT:A:M BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.11825404 97 17 2834 37 101M * 0 0 CCCGAGCAGCAGCCGTCGTGTCTCACCCAGGGTGTCTGAAACAGATGTGGAGGTCTCGGGTGAGGCGTGGCTCAGATACAGGGAGTGGCCCACAGCTCGGC AE<EFC?E?>D>GFDFKGIGIHGFIGEGGC5<@FIHFGFCEKG5)+9<:AA=E9;7/"FC?D@7CK8BE@FDFEAH;96D=52;AE7-A8<88CGAB X0:i:1 X1:i:0 XC:i:82 MD:Z:82 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.52739527 147 17 2867 60 101M = 2567 -400 GTCTGAAACAGATGTGGAGGTCTCGGGTGAGGCGTGGCTCAGATACAGGGAGTGGCCCACAGCTCGGCCTGTCTTTGAAAGGCCACGTGACCTGGCCCACG BGDEGGC9EMIIJHHFIIFDDFHAHFFIGIGH?GIIIGKJMIJIJJMIIJMHIFHLMJJJLKJFCLKEKJIKJMMILJJLKJKFHAHFIH4HGFHEDFF:? X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A +ERR229776.44981660 83 17 2879 60 101M = 2656 -323 TGTGGAGGTCTCGGGTGAGGCGTGGCTCAGATACAGGGAGTGGCCCACAGCTCGGCCTGTCTTTGAAAGGCCACGTGACCTGGCCCACGGCTGGCAGGTGG FEGDHIE?F;G9HHEG>HEA8FIFHGICNGFEBJIKJHHH>CBB8:62:A@6?HGCH37(;9@;?ABD>BF<>CC7,2::8>G)17?GBF-:@CH<;CCHAE=:;DBCAEC@(9>B:?D48AKHFGHFDD:CFIHGFICA#### X0:i:1 X1:i:0 XC:i:98 MD:Z:6G90T0 RG:Z:ERR229776 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.3777343 147 17 2891 60 101M = 2723 -268 GGGTGAGGCGTGGCTCAGATACAGGGAGTGGCCCACAGCTCGGCCTGTCTTTGAAAGGCCACGTGACCTGGCCCACGGCTGGCAGGTGGGACCCAGCTGCA DEAGCHE=>EIHIIKFHDKIIFMHIIIFFFGAECECHFDFAHICGJHLHMKIJJKLHJG:<1<@C6*>EA6*07D;A@D? X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C@ +ERR229776.16418187 83 17 2953 60 8S93M = 2727 -318 AAGGCCACGTGACCTGGCCCACGGCTGGCAGGTGGGACCCAGCTGCAGGGGTCCAGCAGCACCCACAGCAGCCACCTGTGGCAGGGAGGAGCTTGTGGTAC #########GAG=;7FE7:)C>E?;:EF???JBJCE:GEA=9<77IE@<=F?>@BCJKGGJ>97-<5?A?EA@D;HDI@GI;67A7ECBED= X0:i:1 X1:i:0 XC:i:93 MD:Z:93 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.89222254 163 17 2970 60 96M5S = 3189 319 GGGCAGGTGGGACCCAGCTGCAGGGGTCCAGCAGCACCCACAGCAGCCACCTGTGGCAGGGAGGAGCTTGGGGTACAGTGGACAGGCCCTGCCCAGATGGC 05=DFGE/BD@I+:FG?E6EGIJBFG?DEHFH@AFDBGG:ED;DICIHIGHMF1;@ECBD@+<:+>)@9B&=66<:=BB>>>6>DC*?@EC:BEG###### X0:i:1 X1:i:0 XC:i:96 MD:Z:0T69T25 RG:Z:ERR229776 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:CFK@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.25895864 99 17 2976 60 101M = 3273 397 GTGGGACCCAGCTGCAGGGGTCCAGCAGCACCCACAGCAGCCACCTGTGGCAGGGAGGAGCTTGTGGTACAGTGGACAGGCCCTGCCCAGATGGCCCCCCG CECCCG@DEA:DJ@HEGGBB8B@FEHHJAEGII>EBC@D>AGGFHKIIF<@IJIAEA@=>EGIB@EDBCBFA4<D=)8?ACC. X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.74190027 83 17 3014 60 27S74M = 2668 -419 CTGCGGGGGTCCAGCAGCACCCACAGCAGCCACCTGTGGCAGGGAGGAGCTTGTGGTACAGTGGACAGGCCCTGCCCAGATGGCCCCCCGCCTGCCTGTGG ############################D?8789?>6?51:D>5.@4:9<:92:5295A3.38;:37:52DE@CECGEC X0:i:1 X1:i:0 XC:i:74 MD:Z:74 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A +ERR229776.107194084 83 17 3015 60 6S95M = 2742 -367 CCAGCAGCCACCTGTGGCAGGGAGGAGCTTGTGGTCCAGTGGACAGCCCCTGCCCAGATGGCCCCCCGCCTGCCTGTGGAAGTTGACCAGACCATCTGTCA #######??68;7GC=7+0FDEED77(+DG76<3/%*=4-<<1+21"A8;<&<43-:6,5@AACGD?>A@9BB>B8:AIHJBDFC@BDJE9ADEDEECFAA X0:i:1 X1:i:0 XC:i:95 MD:Z:29A10G54 RG:Z:ERR229776 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.60225376 83 17 3018 60 66S35M = 2734 -318 CGGGGCCTGGCCCTGGGCTGGCAGGTGGCCCCCAGCTGCTGGGGTCCAGCAGCCCCCACAGCAGCCACCTGTGGCAGGGAGGAGCTTGTGGTACAGTGGAC ########################################################################7E=CA(5.6;4=DE?= X0:i:1 X1:i:0 XC:i:35 MD:Z:35 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.4450150 163 17 3027 60 101M = 3312 354 AGGGAGGAGCTTGTGGTACAGTGGACAGGCCCTGCCCAGATGGCCCCCCGCCTGCCTGTGGAAGTTGACCAGACCATCTGTCACAGCAGGTAAGACTCTGC ?C@DCGEFFGFIGFHGE@@HIIIIK?FJIFHKMKKIIJHLJLFJJLHII5 X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.49925000 147 17 3075 60 101M = 2880 -295 CGCCTGCCTGTGGAAGTTGACCAGACCATCTGTCACAGCAGGTAAGACTCTGCTTTCTGGGCAACCCAGCAGGTGACCCTGGAATTCCTGTCCATCTGGCA DFCCIKEEIHFAJIHJIFHKFKGEDLB>LIJJMACCJJMJIEJGJJIF4FLIJ@HDDLJJKFFNHJKJIGIJCEIJE@@CBCGJHHHGDHCI@> X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.107791703 147 17 3127 29 30S71M = 2817 -380 AGACCATCTGTCACAGCAGGTAAGCCTCTGCTTTCTGGGCAACCCAGCAGGTGACCCTGGAATTCCTGTCCATCTGGCAGGTGGGCATTGAAACTGGTTTA ###############################IG++HE>E<12.@99BCEF@6EG6BC,E(BF:>:>GELHDAC9@9GEF>G>CAE;& X0:i:1 X1:i:0 XC:i:71 MD:Z:71 RG:Z:ERR229776 AM:i:29 NM:i:0 SM:i:29 MQ:i:29 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.99540436 147 17 3147 60 101M = 2895 -352 GTGACCCTGGAATTCCTGTCCATCTGGCAGGTGGGCATTGAAACTGGTTTAAAAATGTCACACCATAGGCCGGGCACAGTGGCTCACGCCTGTAATCCCAG CDDFEFHKHIFIHHGIJGJGIGJHIFJILGHKIIKKKMJJKKGKKMKNMJLKKKJIHJIFB:LJJJLKKI>LLKIIJLJIJHKJIHAGEIFFGHHIDDDH? X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.89222254 83 17 3189 60 101M = 2970 -319 ACTGGTTTAAAAATGTCACACCATAGGCCGGGCACAGTGGCTCACGCCTGTAATCCCAGCCCTTTGGGAGGCCAGGGTGGGTGGATCACTTGAGGTCAGGA FCEFEJGIFHFHEHHJCGHIDBD@LEB=8@DG>B:>53+14)A:2'DEFGA5-<39?C9DBGK?HEC>ED9#7HA2>C1ED@E6AH<@GD@GCIDBA X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.27664076 99 17 3197 60 101M = 3465 347 AAAAATGTCACACCATAGGCCGGGCACAGTGGCTCACGCCTGTAATCCCAGCCCTTTGGGAGGCCAGGGTGGGTGGATCACTTGAGGTCAGGAGTTCAAGA ABGGGEB;@78DCAFCGH8@F?=6;%806CHHI?H018D0;AGH@HHH<;GAB/?AF8EA)9@H@A@??HBEEGCFF2>:<:GBBF?IF=BHCEFGCJI?=:GFEAIFGHG8DD@HJKJLFBHHI5AJEJFFEE33?E@DJEFIIFHHFIGGHHEHID5DC<JMMBJLKIEKJLLKJIIFKJKKKJLILKIJIJG=EGJIHJI>DGGGHEFFEFC X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@E +ERR229776.31259015 99 17 3281 60 101M = 3514 333 AGGTCAGTATTTCAAGACCAGCCTGGCCAACATGGTGAAACCCCGTCTACTAAAAATACAAAAATTAGCCTGGCGTGGTGGCGCATGCCTGTAATCCCAGC 7<8ACD<-.&)9:<<@7;9@HDCI>>/:<@@HFBBIBAI;=7;DAFC8<-@@==+,BFFC7ADBJBGE:I9;)B?CA;;;=3FFHFBD;HLG################## X0:i:1 X1:i:0 XC:i:84 MD:Z:84 RG:Z:ERR229776 AM:i:0 NM:i:0 SM:i:37 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.32427229 99 17 3347 60 101M = 3572 325 AGCCTGGCGTGGTGGCGCATGCCTGTAATCCCAGCTACTTGGGAAGCTGAGGGATGAGAACTGCTTGAACCTGGGAGGCAGACGTTGCAGTGAGCTGAGAT A@FDIE@E<;BFD@?C?IFEHHFIIEGKEFFJHJKKIHLIHKKDLIKLJKGJLIIIJGEJFIIEKGFFJGFKGEEGBFFIHJFAGCDIJIIHJHILGIFGE X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.26612274 83 17 3349 60 101M = 3093 -356 GCTGGCGTGGTGGCGCATGCCTGTAATCCCAGCTGCTTGGGAAGCTGAGGGATGAGAACTGCTTGAACCTGGGAGGCAGACGTTGCAGTGAGCTGAGATCA #BDDB:FIECE==:A@AJGDA57C;A@='>?CCFEHF?@C@LDF>HHIKHHE4C@DJHH:?FGHAA@?IEDB;D7>@D79G:?BE<9?BICDGAA X0:i:1 X1:i:0 MD:Z:0C33A66 RG:Z:ERR229776 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@F@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.38128366 99 17 3399 60 101M = 3700 401 GATGAGAACTGCTTGAACCTGGGAGGCAGACGTTGCAGTGAGCTGAGATCACGCCACTGCACTCCAGCCTGGGCAACAGAGTAAGACTCTGTCTCAAAAAA =@ECEC9@>E?IDACD8?>HG;C?@=9FCE5?BDCGA>D?>AI=74CH376*:+0;EHKDB->;E;B6,57,I>=FB)20=2490BFGGBDGD?;C,0@07H@0CF10+9D14:CDEEE9@@GCDBD>>@ X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A +ERR229776.27664076 147 17 3465 60 21S80M = 3197 -347 AGACCACGCCACTGCACTCCAGCCTGGGCAACAGAGTAAGACTCTGTCTCAAAAAAAAAAAAATCACACCATTTTGGCTTCAGATTGCATATCCTCCTGCA ######################CDIGFIBHGBG9C>ECG9:6A;.<4:<=ACIIKKJJHLKKIFEEBAJHHCMKJJKIEJGLHAGHHEHGFIGFHEEFEC? X0:i:1 X1:i:0 XC:i:80 MD:Z:80 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A +ERR229776.46260219 147 17 3469 60 101M = 3225 -344 GGGCAACAGAGTAAGACTCTGTCTCAAAAAAAAAAAAATCACACCATTTTGGCTTCAGATTGCATATCCTCCTGCAAGGATATATACGCGTGAAATTCAAG B?@ABG;AFE,=D@>;FG7B956B9AABEDDDKKGIKJLGGGKCJJACFGJMKMKJMMKNKJJIJIGEHCLLIKIJLHIIHHGDHHAJ@GDHHHHJFEBHC X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.51706669 163 17 3478 60 93M8S = 3757 379 AGTAAGACTCTGCCTCAAAAAAAAAAAAATCACACCATTTTGGCTTCAGATTGCATATCCTCCTGCAAGGATATATACGCGTGAAATTCAAGTCAATGAAA BEFFIGIEJHIH:CKHHKGKLLLLLLMLMFBD48?CCC@CHIDHJCGECEDCFAHFAEH@EHGADHIJGAA-6>A@EH6/;3+;CB=DBGJC######### X0:i:1 X1:i:0 XC:i:93 MD:Z:12T80 RG:Z:ERR229776 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.38173578 147 17 3478 60 26S75M = 3262 -290 CCACTGCACTCCAGCCTGGGCAACAGAGTAAGCCTCTGTCTCAAAAAAAAAAAAATCACACCATTTTGGCTTCAGATTGCATATCCTCCTGCAAGGATATA ###########################E@FEB/<:=C?A:DB<>EEA8B;?;@6>A632:CIICIE##################################################################################### XC:i:35 MD:Z:18C6T6T2 RG:Z:ERR229776 AM:i:29 NM:i:3 SM:i:29 MQ:i:29 XT:A:M BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.31259015 147 17 3514 60 101M = 3281 -333 ATTTTGGCTTCAGATTGCATATCCTCCTGCAAGGATATATACGCGTGAAATTCAAGTCAATGACAAATCAGAAGAAAAAACATATATATACGCAAACCAGT C@AHHEHGJGFLIAKJIHFEC=BDI?HJJGDIA?DFCAKIF=L?EKLJKJLC;JLJLHKJJDJAJBF:JLIIIIIHJCIGHHD=EHHCGE9HFCDGC>I@: X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.89637749 163 17 3537 60 101M = 3762 325 CTCCTGCAAGGATATATACGCGTGAAATTCAAGTCAATGACAAATCAGAAGAAAAAACATATATATACGCAAACCAGTATCCTACTGTGTGTGTCGTTTGT ?K+=EFHGJH@JHHHIIGIAKBIIKLMJKLJMLIJJMKJLJKMMKLJCKMJLNNNMMKKKJKJKJKJHBKHFGFEJGHHGIHNIGMIMIJIJIIH@HCCAC X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@E +ERR229776.109591233 147 17 3541 60 101M = 3310 -331 TGCAAGGATATATACGCGTGAAATTCAAGTCAATGACAAATCAGAAGAAAAAACATATATATACGCAAACCAGTATCCTACTGTGTGTGTCGTTTGTTGTG EFECKIJJKKIIIJ?J?GJIFFIHKIELIKHJGKFKJJJJKJMKJMKKLLKKHJJJJJJIIIJAJIJJJLIMIIIJILIIKIHGIHHFGJ:FJJGEIFEGC X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.32427229 147 17 3572 60 101M = 3347 -325 AATGACAAATCAGAAAAAAAAACATATATATACGCAAACCAGTATCCTACTGTGTGTGTCGTTTGTTGTGTTTTCGACAGCTGTCCGTGTTATAATAATTC DEFECGJFIGIMIFFFFFFKFDIKHHJJGDFE?HBIIFDGLGFJKGKJHKIKJKKJKJJ?HJNKIMJJJIMMMKBLIJLKKIIHHAHFGKFHGHHGGFEG? X0:i:1 X1:i:0 MD:Z:15G85 RG:Z:ERR229776 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:B@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A +ERR229776.40459217 99 17 3602 60 35M66S = 3843 307 TACGCAAACCAGTATCCTACTGTGTGTGTCGTTTGCTGTGTTTTCGACAGCCGTCCGCGTTATAATAACCCCCCTACCTCAAATTTATTCACTTTCAACTC =4>@G:=EG=FKHFGG@HE6>FGA?GIIHE?HE6FJFI.:HGFJLJAJ+-5D??B9AAFEEFDD9A1@EBDIDDF?C.CDDHIFGHHHF?8DCICEF X0:i:1 X1:i:0 MD:Z:52C48 RG:Z:ERR229776 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B +ERR229776.104546030 163 17 3615 60 101M = 3837 322 ATCCTACTGTGTGTGTCGTTTGTTGTGTTTTCGACAGCTGTCCGTGTTATAATAATTCCTCTAGTTCAAATTTATTCATTTTTAACTTCATAGTACCACAT CEFEJGEKGHFIHGGHH>HIJIIJIFGIIKKHALJJJMMJJKLBJJGJJJJNKJNKLMMNMNJLJKKJMMKKKKKIHKLFKKKIMHMKIJKKHIHFGGDFE X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@G +ERR229776.37380040 1187 17 3615 60 101M = 3839 322 ATCCTACTGTGTGTGTCGTTTGTTGTGTTTTCGACAGCTGTCCGTGTTATAATAATTCCTCTAGTTCAAATTTATTCATTTTTAACTTCATAGTACCACAT ?EFEIGEJGGAGGCGHC:EGIGIJJEHHIJJIAKIJMIKFJJI?FFGBEIJMJJCGJHJMLMFCECJIMMJKKHHFHILIKKKFEHMKIJHFHHHFFGD:B X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D +ERR229776.83861944 163 17 3622 60 101M = 3858 336 TGTGTGTGTCGTTTGTTGTGTTTTCGACAGCTGTCCGTGTTATAATAATTCCTCTAGTTCAAATTTATTCATTTTTAACTTCATAGTACCACATTCTACAC 4=EAF@DADF9HDG=E?;DEDAACE@EFIHHLJEEH=4A@BACECFELDIDDJIA8CJJKIFDGIGBGHKIFFEJFDDBCHIHFCHHFDEGCHJDHJDJJHNNLBKKKNKMJJLLAJJJMJJJKJJHILKLLKGJLILIGIJILLIHLJGFKKJJHIHJKIGGGEAFBBFAGGECEE=DDEGDA X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:AEAD@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.25245101 99 17 3650 60 101M = 3870 320 AGCTGTCCGTGTTATAATAATTCCTCTAGTTCAAATTTATTCATTTTTAACTTCATAGTACCACATTCTACACACTGCCCATGTCCCCTCAAGCTTCCCCT A@=H=A<@,5:BF=FAIGBC>G?MAB-=GDEDB>A=GIKJKHDEFJJJB4>DACEIC6F?IEH+?@KEAEDDI X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D +ERR229776.38128366 147 17 3700 60 101M = 3399 -401 CTTCATAGTACCACATTCTACACACTGCCCATGTCCCCTCAAGCTTCCCCTGGCTCCTGCAACCACAAATCTACTCTCTGCCTCTGTGGGTTGACCTATTC AHBEKFBFGHFEGCBDFGJJMKJMLFCFKJLLMLIIJKJKJIHJIJJJKJIIHDHJJIHHJJCIIHJGEIGFFEGFEEGB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.45938508 99 17 3704 60 97M4S = 4005 401 ATAGTACCACATTCTACACACTGCCCATGTCCCCTCAAGCTTCCCCTGGCTCCTGCAACCACAAATCTACTCTCTGCCTCTGTGGGTTGACCTATTCTGGA BEECEE@D?@;GGHGBFG@CGD>C>:BEE=8BBC>CEGDFHEGHJJKH@2;?>H>9FFGI.0A?IGJM5B.;IEHGJ=GD:1319:GFBFBHD@FG##### X0:i:1 X1:i:0 XC:i:97 MD:Z:97 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.94413412 147 17 3754 29 1S100M = 3490 -363 CCCCTGCAACCACAAATCTACTCTCTGCCTCTGTGGGTTGGCCTATTCTGGACACGTCATAGAAATAGAGTCCTGCAACACGTGGCCGTCTGTGTCTGGCT ##?>@E>6AA@CHDGE;FBH<9<->:>BD>CHDC?EC6G-+@CD8IBB/>DDF?;A:FFDMGHFIDLJKGJCCHAIADF?2+D=??G>6?=44:B>>(:F>=97-$65=.6:<: X0:i:1 X1:i:0 XC:i:46 MD:Z:37A8 RG:Z:ERR229776 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.51706669 83 17 3757 60 101M = 3478 -379 TGCAACCACAAATCTACTCTCTGCCTCTGTGGGTTGACCTATTCTGGACACGTCATAGAAATAGAGTCCTTCAACACGTGGCCGTCTGTGTCTGGCTTCTC H6<6>CDGHFD>AIGHEH?A;HB;.;A12000BC<=:D1FJEIGFEIIGHKHGHH?91'::G@E?FCFD57GHCGFGEDCDD?.<0(,9+<2+7E@@/CAFHHIFJFE4GIICE<3HFFC-CBA<7GFIEC6GIJEFGGGGAD@+DFEDEFDIHJJAJLKKHJKLKKLMMMKKLMKCLMMJMLKJKJMIILLKKJJKJIJJIJEGGFHKDFEFC X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.21787291 163 17 3825 37 98M3S = 4149 374 CTGCAACACGTGGCCGTCTGTGTCTGGCTTCTCTCGCTTAGCATCTTGTTTCCAAGGTCCTCCCACAGTGTAGCATNCACCTGCTACACTCCTTCTTAGGG ?HDEFFDGF>>F6@H?IIIHJJJLMKBCFJ@DFLFCGHJJJJIBC757?FHCDFF#67:FH8CIHHJHIDHLHHJF#### X0:i:1 X1:i:0 XC:i:98 MD:Z:76G21 RG:Z:ERR229776 AM:i:0 NM:i:1 SM:i:37 MQ:i:0 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.104546030 83 17 3837 60 101M = 3615 -322 GCCGTCTGTGTCTGGCTTCTCTCGCTTAGCATCTTGTTTCCAAGGTCCTCCCACAGTGTAGCATGCACCTGCTACACTCCTTCTTAGGGCTGATATTCCAC C?>EIHIGICJIJFHHHJHHHI@JJMJNJKJLJLJJMMLIJIKIIKIHKIAHHKLHHIILJHIGFF@JJHFIHGD;HBHIJGHJGHHHGGBBDEBGFCCDC X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.37380040 1107 17 3839 60 2S99M = 3615 -322 GCCGTCTGTGTCTGGCTTCTCTCGCTTAGCATCTTGTTTCCAAGGTCCTCCCACAGTGTAGCATGCACCTGCTACACTCCTTCTTAGGGCTGATATTCCAC ###BIHIGICGDG=)HJHDEHI<@GGEIAGBKHLJGMKKIFKJD@DDEEG>F>EK@ICILJJHHHF;JHHFEEGC8JI=IHGDJGAFEGGB@@EBGFBEDC X0:i:1 X1:i:0 XC:i:99 MD:Z:99 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.40459217 147 17 3843 60 34S67M = 3602 -307 GGATAGAAATAGAGGCCTGGAACGCGTGGCCGTCTGTGTCTGGCTTCTCTCGCTTAGCATCTTGTTTCCAAGGTCCTCCCACAGTGTAGCATGCACCTGCT ###################################CG?+GB*7*C;F;4=HF;?F3@ECBCF(ECKHGG>9HB@<@9>9BEACF-8EE907EED?: X0:i:1 X1:i:0 XC:i:67 MD:Z:67 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.83861944 83 17 3858 60 101M = 3622 -336 TCGCTTAGCATCTTGTTTCCAAGGTCCTCCCACAGTGTAGCATGCACCTGCTACACTCCTTCTTAGGGCTGATATTCCGCGCACCTGCTACACTCCTTCTT D;GFIF=CD>D:CJHIJJEHGJD:<9:8?<:9JEHEE?<>A?BD6?C>.EJ??>AGJBGFB8694BAHHF@>?<>=9=D=F@B<3+7G@EGFB:9 X0:i:1 X1:i:0 MD:Z:78A22 RG:Z:ERR229776 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.22665016 83 17 3861 60 3S98M = 3604 -354 TCGCTTAGCATCTTGTTTCCAAGGTCCTCCCACAGTGTAGCATGCACCTGCTACACTCCTTCTTAGGGCTGATATTCCGCGCACCTGCTACACTCCTTCTT ####HHI?9>A+CJHJIIA377&041;57:=D;=3++.(:>CB=;+ X0:i:1 X1:i:0 XC:i:98 MD:Z:75A22 RG:Z:ERR229776 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.26430745 99 17 3863 60 101M = 4142 374 TAGCATCTTGCTTCCAAGGTCCTCCCACAGTGTAGCATGCACCTGCTACACTCCTTCTTAGGGCTGATATTCCACGCACCTGCTACACTCCTTCTTATGGC BEEEEEBIE>-EFFHEJHH@IFGHJHHHBCBFCCIJIIFJHHKIJKKIGI@MKLMKLJKDJBFFLJKJIDJKIJJCKIIGMHKMKGJGMIHHHHKGGDF;> X0:i:1 X1:i:0 MD:Z:10T90 RG:Z:ERR229776 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.25245101 147 17 3870 60 101M = 3650 -320 TTGTTTCCAAGGTCCTCCCACAGTGTAGCATGCACCTGCTACACTCCTTCTTAGGGCTGATATTCCGCGCACCTGCTACACTCCTTCTTATGGCTGATATT CDDHHIDHFB@,;@DICEHHEFEHHJLFE?D??ABCCGCDGCFGEJKMKHKJMIICIIFJJILKC?H?EF=IJIIJGFFAH>CB@IIHHHBGFFGGEEFA? X0:i:1 X1:i:0 MD:Z:66A34 RG:Z:ERR229776 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.106927739 99 17 3903 20 101M = 4098 295 ACCTGCTACACTCCTTCTTAGGGCTGATATTCCGCGCACCTGCTACACTCCTTCTTATGGCTGATATTCCACGCACCTGCTACACTCCTTCTTAGGGCTGA CDEIEEFECAAIGHIFIJGEJIHJJIJHAEHKJ8IAJHFKKHKKIJIILLELKMMKGAJJIIJHGHGIHHIG;HHCGJHHLHGCGLIELFILHC=>BBJ@G X0:i:1 X1:i:2 XA:Z:17,+4162,101M,2;17,+4088,101M,2; MD:Z:33A67 RG:Z:ERR229776 AM:i:0 NM:i:1 SM:i:20 MQ:i:1 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C +ERR229776.86454710 161 17 3912 37 101M * 0 0 ACTCCTTCTTAGGGCTGATATTCCGCGCACCTGCTACACTCCTTCTTATGGCTGATATTCCACGCACCTGCTACACTCCTTCTTAGGGCTGATATTCCACA CEIFEKHGJHFIHJIKIJIIIJJK@KBLJJKLJKLIHJIJJIMKMMKIFHJJKJLJFJKLLJI=KJHE@JICDF-DIF9## X0:i:1 X1:i:0 XC:i:100 MD:Z:100 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ diff --git a/test/mpileup/mpileup.3.bam b/test/mpileup/mpileup.3.bam new file mode 100644 index 0000000000000000000000000000000000000000..90b325eeab72c40a2a16ba92c1349085145e2eb7 GIT binary patch literal 27569 zcmV)MK)AmjiwFb&00000{{{d;LjnLg1jSX)bJ{oq;)$nQXt(FJ8R4JclaydZTf5~nhFTjI@TwH$}Q z`3|7o0@wxW0yJ|H;YAeFy(FM1VdZ2!VNQ}KsU9dCO2^l)sHg>YObArQ6D@HZrF54* zc`kj)>_h&s&V>(4I%0E?@#qg4Vt>nv$BHbA^OBsPD`~+NG{6UD8f{BAjE{m|xfX09 zdIwbBUDpWx3##cnV+ByTY8g6qId9i~~kVkuf3Dh^ARWdnt+U^Clm|{%byHnxBp?et6sld54R_~ylVA>?1NE9P@D#2kf~p7Rl*G|8rOcC5`db1( zo$r^zrD&E+^Q{HyO`6@MpecW3NAG4tOH@6{S+i}Lgr)^2m95hd*Y`YE@QWh7y?9$B zuM{|3v<;f2by9&{B{fHZx@BmW+WeYK>UcT;TB`%pB;ym{vornMaq-j{e*g8o1KzwBmj4E=3?-mW(;iSV#-wo?;+Ar8+A|@9U}vsAQM3iL5QG^U>m^> zf?WiU5i}4yLC{3HhIGD1NB^L2XyUyW@^8cm2}fL^RaMJ2{$X|2~MH z#s*Qk4yxGWv%yP@e8$80b_9>duG4gF;8^YykZk&>0#4evIwZ>sZL;-|oFAFAMt9hlcMIclnU{wE_;^>i+HCl`h5!>qTp+9Y!7;#J$10_&248ibo$>;U3)xq zyhjuXyTRdl6?2BWTjDXt0QU*qzS3;o#JpUk$-z z$SL<-e8K6S$_F`J$MNfH5|mr;KrK&-{XevS*Jw0;;~!`=zW>o^{0E)$m{>9k001A0 z2m}BC000301^_}s0sy*A)xBwqBx!mcR@2k>SrHXg8JTf@_ZJbF!@3VbvMaK4rgK+Z za+e%Z%O#iGV`g`bU6Wi>l4T20S1QC!in2&yX_*j3%Ldn$FTn&&QIIUkG$0d@YyvbO zOQHb_G;E9ZAAyi<$OH)4@AG9HnOWK0)oo9ADZ4APDl@BR@Wh+X_q_KPUt2o8tt21w zuPpui(!0k$e~rHWd-{6wJHK;t^I&gp=Z($H_3eZGovo#-*Orz(NxvHOM}a@GV{5~j z4eG%t9QK2LQ`fd&mS6MslSx5sN(Gwy>%t6T_rrCd>0y zqD{u=*-n(N+(=T+!ywDjTi)H(wRkmseKlu7i&d>nsiijbMiVn-OWPJQ7tADFS^0^< zXEryMzVp#%PXFJR>Q6jOzWoyqm%fW0Kk=!D$*140KhgixXAb{=zP@4olJ zd*A!TcRu&U&wu%|UwHSucb2{|1+(v9{^BXjze``=|JpRn+q+vkTkG3PKTWUvDj_|# z_#e;rs8u{}sCX>Id}G2Oqru;rkza6>s?v z_h0$&y{~@w75t@le?U)t<%4%W_s*BU^py{O=)*6+`=$5a`^tMCy!-CE@BH9rmcIBD zWBxt*`oS5L_jWfnx3@Pomi{)q^iu@$ys7rXAS8&%vcrathuroXuW2S218m0gj0vkG zfx#F7V{~DpE$E>D?6xTB0^q^&(#R~LA4(3ewYA-nej}Dz(uJsSUFa$h_^INC_iUx; z(~zn%r%wuudH>+KjhPJbOYeXAo%i0ShxY;dd+&enHY72=S%O

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+++ b/test/mpileup/mpileup.3.out @@ -0,0 +1,30 @@ +##fileformat=VCFv4.2 +##FILTER= +##contig= +##ALT= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##FORMAT= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT HG00100 +17 1050 . A <*> 0 . DP=6;I16=6,0,0,0,232,9002,0,0,360,21600,0,0,113,2597,0,0;QS=1,0;MQ0F=0 PL 0,18,152 +17 1051 . A <*> 0 . DP=5;I16=5,0,0,0,191,7317,0,0,300,18000,0,0,115,2675,0,0;QS=1,0;MQ0F=0 PL 0,15,135 +17 1052 . A <*> 0 . DP=5;I16=5,0,0,0,189,7223,0,0,300,18000,0,0,117,2757,0,0;QS=1,0;MQ0F=0 PL 0,15,135 +17 1053 . A <*> 0 . DP=5;I16=5,0,0,0,187,7027,0,0,300,18000,0,0,119,2843,0,0;QS=1,0;MQ0F=0 PL 0,15,133 +17 1054 . C <*> 0 . DP=5;I16=5,0,0,0,184,6852,0,0,300,18000,0,0,121,2933,0,0;QS=1,0;MQ0F=0 PL 0,15,132 +17 1055 . C <*> 0 . DP=7;I16=7,0,0,0,255,9635,0,0,420,25200,0,0,123,3027,0,0;QS=1,0;MQ0F=0 PL 0,21,161 +17 1056 . C <*> 0 . DP=7;I16=7,0,0,0,252,9454,0,0,420,25200,0,0,127,3127,0,0;QS=1,0;MQ0F=0 PL 0,21,159 +17 1057 . T <*> 0 . DP=7;I16=7,0,0,0,269,10389,0,0,420,25200,0,0,129,3133,0,0;QS=1,0;MQ0F=0 PL 0,21,164 +17 1058 . G <*> 0 . DP=7;I16=7,0,0,0,281,11297,0,0,420,25200,0,0,131,3143,0,0;QS=1,0;MQ0F=0 PL 0,21,170 +17 1059 . T <*> 0 . DP=7;I16=7,0,0,0,257,9509,0,0,420,25200,0,0,133,3157,0,0;QS=1,0;MQ0F=0 PL 0,21,157 +17 1060 . C <*> 0 . DP=7;I16=7,0,0,0,268,10392,0,0,420,25200,0,0,135,3175,0,0;QS=1,0;MQ0F=0 PL 0,21,164 diff --git a/test/mpileup/mpileup.3.sam b/test/mpileup/mpileup.3.sam new file mode 100644 index 0000000..e40039d --- /dev/null +++ b/test/mpileup/mpileup.3.sam @@ -0,0 +1,250 @@ +@HD VN:1.0 SO:coordinate +@SQ SN:17 LN:4200 M5:a9a06ca09c111789d92723fbf39820f6 AS:NCBI37 SP:Human +@RG ID:ERR229775 LB:HG00102_I_bc_pelib_1019 SM:HG00102 PI:497 CN:MPIMG PL:ILLUMINA DS:SRP001294 +@PG ID:bwa_index PN:bwa VN:0.5.9-r16 CL:bwa index -a bwtsw $reference_fasta +@PG ID:bwa_aln_fastq PN:bwa PP:bwa_index VN:0.5.9-r16 CL:bwa aln -q 15 -f $sai_file $reference_fasta $fastq_file +@PG ID:bwa_sam PN:bwa PP:bwa_aln_fastq VN:0.5.9-r16 CL:bwa sampe -a 1491 -r $rg_line -f $sam_file $reference_fasta $sai_file(s) $fastq_file(s) +@PG ID:sam_to_fixed_bam PN:samtools PP:bwa_sam VN:0.1.17 (r973:277) CL:samtools view -bSu $sam_file | samtools sort -n -o - samtools_nsort_tmp | samtools fixmate /dev/stdin /dev/stdout | samtools sort -o - samtools_csort_tmp | samtools fillmd -u - $reference_fasta > $fixed_bam_file +@PG ID:gatk_target_interval_creator PN:GenomeAnalysisTK PP:sam_to_fixed_bam VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T RealignerTargetCreator -R $reference_fasta -o $intervals_file -known $known_indels_file(s) +@PG ID:bam_realignment_around_known_indels PN:GenomeAnalysisTK PP:gatk_target_interval_creator VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T IndelRealigner -R $reference_fasta -I $bam_file -o $realigned_bam_file -targetIntervals $intervals_file -known $known_indels_file(s) -LOD 0.4 -model KNOWNS_ONLY -compress 0 --disable_bam_indexing +@PG ID:bam_count_covariates PN:GenomeAnalysisTK PP:bam_realignment_around_known_indels VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T CountCovariates -R $reference_fasta -I $bam_file -recalFile $bam_file.recal_data.csv -knownSites $known_sites_file(s) -l INFO -L '1;2;3;4;5;6;7;8;9;10;11;12;13;14;15;16;17;18;19;20;21;22;X;Y;MT' -cov ReadGroupCovariate -cov QualityScoreCovariate -cov CycleCovariate -cov DinucCovariate +@PG ID:bam_recalibrate_quality_scores PN:GenomeAnalysisTK PP:bam_count_covariates VN:1.2-29-g0acaf2d CL:java $jvm_args -jar GenomeAnalysisTK.jar -T TableRecalibration -R $reference_fasta -recalFile $bam_file.recal_data.csv -I $bam_file -o $recalibrated_bam_file -l INFO -compress 0 --disable_bam_indexing +@PG ID:bam_calculate_bq PN:samtools PP:bam_recalibrate_quality_scores VN:0.1.17 (r973:277) CL:samtools calmd -Erb $bam_file $reference_fasta > $bq_bam_file +@PG ID:bam_merge PN:picard PP:bam_calculate_bq VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +@PG ID:bam_mark_duplicates PN:picard PP:bam_merge VN:1.53 CL:java $jvm_args -jar MarkDuplicates.jar INPUT=$bam_file OUTPUT=$markdup_bam_file ASSUME_SORTED=TRUE METRICS_FILE=/dev/null VALIDATION_STRINGENCY=SILENT +@PG ID:bam_merge.1 PN:picard PP:bam_mark_duplicates VN:1.53 CL:java $jvm_args -jar MergeSamFiles.jar INPUT=$bam_file(s) OUTPUT=$merged_bam VALIDATION_STRINGENCY=SILENT +ERR229775.22049853 163 17 1 29 80S21M = 115 213 AGGCTCAGACTCCTTTCTCTATGACAGGGAGGTCATGTGCAGGCTGGAGAAGGGGACAAGAGGGCCCCAACTTCTTTGCAAAGCTTCTCACCCTGTTCCTG BDBDHECFF@D=DA>CIJIF8E>HBEEBH@AA8>GH@BIJI;?CC95@@?*2-67=6?$6ABDGD6GGHKGEGHIJIH=BFIKI:DEADBH>CFIE MD:Z:21 RG:Z:ERR229775 AM:i:29 NM:i:0 SM:i:29 MQ:i:29 XT:A:M BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ihg\aehjhYcd`cag]behd +ERR229775.4635304 99 17 1 29 9S92M = 250 348 TTCTTTGCAAAGCTTCTCACCCTGTTCCTGCATAGATAATTGCATGACAATTGCCTTGTCCCTGCTGAATGTGCTCTGGGGTCTCTGGGGTCTCACCCACG BFFKGHHHIKIIIKIKLKIILHMKJJLLMILJJJMLJJNKLLMKKJLJKNKLKILNKLKMLINLMNLMNKJJKLNKMKFAEHGMKPLHFGJIMIKFFFE@; MD:Z:92 RG:Z:ERR229775 AM:i:29 NM:i:0 SM:i:29 MQ:i:29 XT:A:M BQ:Z:@@@@@@@@@jhhhjhjkjhhkgljiikklhkiiilkiimjkkljjikijmjkjhkmjkjlkhmklmklmjiijkmjlje`dgfljokgefihlhjeeed_Z +ERR229775.76124411 163 17 1 29 12S89M = 253 351 AACTTCTTTGCAAAGCTTCTCACCCTGTTCCTGCATAGATAATTGCATGACAATTGCCTTGTCCCTGCTGAATGTGCTCTGGGGTCTCTGGGGTCTCACCC @BDIFEFFEBBGJIHGJHEIJHGJJKIIIIJKHHIIIJKICKHE@>1;<=E?CG?F X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@H +ERR229775.71066602 99 17 35 60 101M = 291 355 ATGACAATTGCCTTGTCCCTGCTGAATGTGCTCTGGGGTCTCTGGGGTCTCACCCACGACCAACTCCCTGGGCCTGGCACCAGGGAGCTTAACAAACATCT BEFHDHJHHHFGLIJIJKKLJKLKKMJIIHJLKMJJLMGGLJMJMMMEJMMKKMMKJ?LKLJMHNJIIMHCFHGMFCIJDHJICAIDJJFIHGGIBBHEEI X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@E +ERR229775.57643739 113 17 39 37 101M * 0 0 CAATTGCCTTGTCCCTGCTGAATGTGCTCTGGGGTCTCTGGGGTCTCACCCACGACCAACTCCCTGGGCCTGGCACCAGGGAGCTTAACAAACATCTGTCC DEEFHE@C?HCHHAIJIIJIHCJEIE;JHFEEFHKFJFJIEGIJGH>9KJD@;EFCJIFA=JFICKIDCFJGFC?IIJHHHKHB@IICIICGCGJGDDH?? X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.24343576 163 17 62 60 101M = 322 360 GTGCTCTGGGGTCTCTGGGGTCTCACCCACGACCAACTCCCTGGGCCTGGCACCAGGGAGCTTAACAAACATCTGTCCAGCGAATACCTGCATCCCTAGAA @DCDHCFB>,,FGDGFHGC@FHFIHGIKH@2JGH@JGJ?EJHCA5?BLIHEJHIGFEB@BG;BBEDGIEDGGGL;FGFI;A37F9F2=@JCDKHJGAIGFEEEE X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.48988007 99 17 115 60 101M = 371 356 CAGGGAGCTTAACAAACATCTGTCCAGCGAATACCTGCATCCCTAGAAGTGAAGCCACCGCCCAAAGACACGCCCATGTCCAGCTTAACCTGCATCCCTAG ?GDCCIGFKGFKGHKKHGIKJIIKGJHIACKFGHCKHJJJFIILGFGMK@CKFIHHJHI>JIFJMEGADJG>FEHJIIIFHJHIMDHKGIH?CJGGFFIE8 X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.22049853 83 17 115 29 1S100M = 1 -213 CCAGGGAGCTTAACAAACATCTGTCCAGCGAATACCTGCATCCCTAGAAGTGAAGCCACCGCCCAAAGACACGCCCATGTCCAGCTTAACCTGCATCCCTA ##IDEBEBHKIDCIFDIFGKD?EHA>BA;GJHIABEGEFGIBDGIKGJMGJIJKHGHKJALJJIJ@DCECE>EIIIHHIKDEFHIEHGHHGHGFEECCD@7 X0:i:1 X1:i:0 XC:i:100 MD:Z:100 RG:Z:ERR229775 AM:i:29 NM:i:0 SM:i:29 MQ:i:29 XT:A:U BQ:Z:@@B@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.6535575 163 17 136 60 101M = 400 364 GTCCAGCGAATACCTGCATCCCTAGAAGTGAAGCCACCGCCCAAAGACACGCCCCTGTCCAGCTTAACCTGCATCCCTAGAAGTGAAGGCACCGCCCAAAG @:9D&@9/0<98DBCCGCDG:?E=>D><+/;7A:=HE71)61>4:KDDIKLJJGJH=6GAIGEIHCHGB@?>HBFHGHBGDFKFGKHGFCFFGBBEJFIJMIFIHJJJLIDFF@HDKHEHGFEHLHHDEFDB X0:i:1 X1:i:0 XC:i:99 MD:Z:99 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A +ERR229775.74734077 163 17 164 60 101M = 421 357 TGAAGCCACCGCCCAAAGACACGCCCATGTCCAGCTTAACCTGCATCCCTAGAAGTGAAGGCGCCGCCCAAAGCCACGCCCATGTCCAGCTTATTCTGCCC 7+>C1A5?-3&B<:EA:(86>A4F8=B<7>7D52@7=>CAE5DK.DCF>(-706B=ACA>D<@IE4:D;CG;@BH9@GH@CCJ@G=B@;ED9E@BHDBFHGI;5ABFHFIG=FCE/=GHHEJGJF X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@H +ERR229775.86942903 99 17 232 60 71M1I29M = 471 339 CAAAGACACGCCCATGTCCAGCTTATTCTGCCCAGTTCCTCTCCAGAAAGGCTGCATGGTTGACACACAGTAGCCTGCGACAAAGCTGAATGCTATCATTT AGHIGIEGD>BGHFHHIKKILKMIIIHIKHJKLCEFJJFMDLJIFHKLLKDJGBEGGJ?@GFIIKIH?GGHDDACIB?>DDJFGII1?,9ED*@>D@FCE= X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C@ +ERR229775.4635304 147 17 250 29 53M1I47M = 1 -348 CAGCTTATTCTGCCCAGTTCCTCTCCAGAAAGGCTGCATGGTTGACACACAGTAGCCTGCGACAAAGCTGAATGCTATCATTTAAAAACTCCTTGCTGGTT EIGGGHHHHCJICGIMGCJGHKCFDJOJJKKIJKKKJIKJJMIIJJJHEHIGILLLLGLBGDJJJLKGIKHGIIKHHJHHKIFHHCG;HFBCGFBEFCDGB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR229775 AM:i:29 NM:i:1 SM:i:29 MQ:i:29 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@IG +ERR229775.76124411 83 17 253 29 50M1I50M = 1 -351 CTTATTCTGCCCAGTTCCTCTCCAGAAAGGCTGCATGGTTGACACACAGTAGCCTGCGACAAAGCTGAATGCTATCATTTAAAAACTCCTTGCTGGTTTGA DDFFFGHJIGHINGDIGDJIJAINKELOIJLKKKKKMJLKKGJKJKLNKKNMMMKLBLJLLLNMMJKKJKKJJJKKJLLIJJHE@KJJJKFHIHFEIIHFB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR229775 AM:i:29 NM:i:1 SM:i:29 MQ:i:29 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.72556128 147 17 262 60 41M1I59M = 22 -339 CCCAGTTCCTCTCCAGAAAGGCTGCATGGTTGACACACAGTAGCCTGCGACAAAGCTGAATGCTATCATTTAAAAACTCCTTGCTGGTTTGAGAGGCAGAA DDFJEGJGC@IKEINIFFMHKHIJKKKIIMJKJJJLKKMJJLKKMJLCKKFKKMLLJKJIIKKIIKJHKLGHIGC>HHIJKFHHHGGIJGBEEJAEEIFEB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:CBA@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@GG +ERR229775.73749010 147 17 283 60 5S20M1I75M = 28 -349 AAAGGCTGCATGGTTGACACACAGTAGCCTGCGACAAAGCTGAATGCTATCATTTAAAAACTCCTTGCTGGTTTGAGAGGCAGAAAATGATATCTCATAGT ######G?<7G9;+@-DEI=CHOHKOFBHE9BHKFE>JHDH9?GHFDCBKCIHA;E=C;9>@A7HA?;AGADHBGHGG@@:>8HG?D9DF6/;@=>:BBA;FEFGH:A7E<&>HAJEIEKKKJGMIJGILKMGNLLKLKIEIJHDIEFE X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@G +ERR229775.65476258 99 17 324 60 101M = 548 324 TATCATTTAAAAACTCCTTGCTGGTTTGAGAGGCAGAAAATGATATCTCATAGTTGCTTTACTTTGCATATTTTAAAATTGTGACTTTCATGGCATAAATA BFFFGHHHHKIJKELKKKJJJLKLIIJIKLLJJLJMLMMNKLLKFJMNMKKJMKKLMNLLKKNLKLMKKKKLLKJNNNLILKLMJNLLKLKIEIKHGHGFE X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@G +ERR229775.44063798 163 17 331 60 101M = 608 377 TAAAAACTCCTTGCTGGTTTGAGAGGCAGAAAATGATATCTCATAGTTGCTTTACTTTGCATATTTTAAAATTGTGACTTTCATGGCATAAATAATACTGG @92:9C:E>:EFG>H@ X0:i:1 X1:i:0 MD:Z:0A100 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:ZS@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.59467859 147 17 359 60 101M = 159 -300 GAAAATGATATCTCATAGTTGCTTTACTTTGCATATTTTAAAATTGTGACTTTCATGGCATAAATAATACTGGTTTATTACAGAAGCACTAGAAAATGCAT DGCDGIEEDKK>LIKHIGMJFHLNJFHLIJAJIIFMMHDIJHGIHIJLIC?LJIEDCA=<3AJIHID)MJGD=@?<8*4JCCA8@928-=92)2@975E)BFE8-;L>CFC>8K?E=8''?@9A>6C694*%;,/44* X0:i:1 X1:i:0 MD:Z:4A25A63C5T0 RG:Z:ERR229775 AM:i:37 NM:i:4 SM:i:37 MQ:i:60 XT:A:U BQ:Z:B@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.70199275 99 17 391 29 101M = 711 374 ATATTTTAAAATTGTGACTTTCATGGCATAAATAATACTGGTTTATTACAGAAGCACTAGAAAATGCATGTGGACAAAAGTTGGGATTAGGAGAGAGAAAT ?EFGGHHFFIEIIEF?C@ABICJICEIJJJLLJJM?H>HHCFI:G>AEHJILLFHGCMJGLKEM>-5A8BKE;JIJHFH4AEIAGMJDF@EHKJHJLHD9JKJN?JLFAG=GMGKKJIAJAJGHI@JGIKKIMHLIIGDILHIF>CGJJLGDC8DHHLGFGFE? X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:FE@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.5711913 163 17 409 60 101M = 646 337 TTTCATGGCATAAATAATACTGGTTTATTACAGAAGCACTAGAAAATGCATGTGGACAAAAGTTGGGATTAGGAGAGAGAAATGAAGACATATGTCCACAC <@CDFD@A?HIIGFJKJLLIFIFCGIFEEDF@KMC?EI=<<GGCDEEFDD7 X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.22701711 163 17 421 29 101M = 699 375 AATAATACTGGTTTATGACAGAAGCACTAGAAAATGCATGTGGACAAAAGTTGGGATTAGGAGAGAGGAATGAAGACATATGTCCACACAAAAACCTGTTC 93:<>>FC'?IHGIKH7KCHCGJFFJHEFCHJJMCLAHJDHKHMGHMLMEF@IBFIHI@DA:HCIGFA83>=0HHEG7 X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:C@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.52216469 163 17 454 60 101M = 693 339 ATGCATGTGGACAAAAGTTGGGATTAGGAGAGAGAAATGAAGACATATGTCCACACAAAAACCTGTTCATTGCAGCTTTCTACCATCACCAAAAATTGCAA @CEEFFBFE:<>:MEMIMED1N?LLQKQD9)@GNLKB@GHGFA;>A>D>;A;H=?B5DIEAFEC>-(7@C8BAD5>7 X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@C@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.82457097 99 17 474 60 101M = 695 321 GGATTAGGAGAGAGAAATGAAGACATATGTCCACACAAAAACCTGTTCATTGCAGCTTTCTACCATCACCAAAAATTGCAAACAACCACACGCCCTTCAAC A?HGGHHFIGHIJFJLLDEJLJKIJIIIGJLMJHIHKMNNNJMNLJJMKKJJMKMMMLLLNJJMKKLKJMKNNNNIKKIIKMJMHGFKGHC?FEHLDFGDB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:CA@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.93698964 99 17 499 60 101M = 735 336 TATGTCCACACAAAAACCTGTTCATTGCAGCTTTCTACCATCACCAAAAATTGCAAACAACCACACGCCCTTCAACTGGGGAACTCATCAACAACAAACTT BFFGHGFHFHEIKKKLIKLIIJLJJKKLJLIMKKMMJKMKKMKKMKNNMNKLLMKNNKKNKMKJKKBKJIOJKKGINHGEGHHGMIJIIJIGJHFIBFDHD X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@CC +ERR229775.17900575 99 17 527 60 101M = 760 333 AGCTTTCTACCATCACCAAAAATTGCAAACAACCACACGCCCTTCAACTGGGGAACTCATCAACAACAAACTTGTGGTTTACCCACACAATGGAAGACCAC BEGKGHGLHFDIIGIIKILLLLIKKLJMLIJKILJIKJBMMMNKLKMKNLMMMJLJMMKKKJLIJMHKMIEMJHJICJFDFHIHJGGGKDIIGJGHIDEFB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.65476258 147 17 548 60 101M = 324 -324 ATTGCAAACAACCACACGCCCTTCAACTGGGGAACTCATCAACAACAAACTTGTGGTTTACCCACACAATGGAAGACCACTTAGCAACAAAAAGGACCAAA BCGGGE@GIAJGDGIHAIGFKNMJKKJKJHKLJGKKJJLKKJJHIKKJJKGJJJKILGGHBHFBHHJIHIGF:KGBJIEJKFFHGAGGHGBBHD;DCEEEA X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@CA +ERR229775.83749675 163 17 553 60 100M1S = 783 330 AAACAACCACACGCCCTTCAACTGGGGAACTCATCAACAACAAACTTGTGGTTTACCCACACAATGGAAGACCACTTAGCAACAAAAAGGACCAAACTCCT ?<:GH:?I59=G@JHHDC3D'6@?ACFHI:E?>;BG=BECFIBH:6?E<6?GDEDHDCHDE65?=GE## X0:i:1 X1:i:0 XC:i:100 MD:Z:100 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B@@ +ERR229775.19017039 99 17 560 60 101M = 839 368 CACACGCCCTTCAACTGGGGAACTCATCAACAACAAACTTGTGGGTTACCCACACAATGGAAGACCACTTAGCAACAAAAAGGACCAAACTCCTGGTACAT ?GDB=1GFFK:GHGH=F?G=CHJJ?DJLGGDGCCC6CIEA?.@E9 X0:i:1 X1:i:0 MD:Z:44T56 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.78639790 147 17 590 60 101M = 335 -355 CAACAAACTTGTGGTTTACCCACACAATGGAAGACCACTTAGCAACAAAAAGGACCAAACTCCTGGTACATGCAACTGACAGATGAATCTCAAACGCATTC CFDGCCHEBGDGFDBKCACBCBC?HKIKDGKLEJJGDHMDG45?IIFIHDEDHIBHA:94'ECEFHC=EH>BFGB@@?:?CEFFFBKJG=JD>EIGFGHHLGBECIKJJ?JLBG=JHGHIIIJMHKKIJGIIC5FGIJGGEIGGFEFIEEHE7 X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@G@ +ERR229775.47649789 147 17 647 60 101M = 392 -355 AACTCCTGGTACATGCAACTGACAGATGAATCTCAAACGCATTCCTCCGTGTGAAAGAAGCCGGACTCACAGGGCAACACACTATCTGACTGTTTCATGGG 68BIAGJE?C?=8JI=5@EIEJHLJJIHGGGBGC?=.?JBAAG=A4EAHJ=FFJJJKJLHH@KJIDHB=HF>?FF>HF@FH;DGI@GAGF7@;@=;3?DBA X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A +ERR229775.52216469 83 17 693 60 101M = 454 -339 CCGTGTGAAAGAAGCCGGACTCACAGGGCAACACACTATCTGACTGTTTCATGGGAAAGTCTGGAAACGGCAACACCATTGAGACAGAAAACAGGTGAGTG C=DHEIHFFLIANGFAKIJLMIILOKJJKLLKKKKNKKMMKLKMKKNNLLKKMMMLLNHKMKMKJJJCKLKJIJILKIMJLLKGJLKFIIGHKFFHFKEHB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D +ERR229775.82457097 147 17 695 60 101M = 474 -321 GTGTGAAAGAAGCCGGACTCACAGGGCAACACACTATCTGACTGTTTCATGGGAAAGTCTGGAAACGGCAACACCATTGAGACAGAAAACAGGTGAGTGGT ?HEFAC>LEAG@C=A@GKKCFHLJJKKJHFCHGKJJJEIGJMJEKFIJJJCHIJKMIFJIFFJJI@FHGH>>;HEEIFCJJ=DJGCGBBEEACFBICEDDB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D +ERR229775.22701711 83 17 699 29 3S98M = 421 -375 TGTGAAAGAAGCCGGACTCCCAGGGCAACACCCTATCCGACTGTTTCCTGGGAAAGTCTGGCAACGGCCACACCATTGAGACAGACAACAGGTGAGTGGTT ####FCGEAFD7::.:DB;'=CB+D@BFFF;2C<,8-%H@C@FI;F-+KIHDCB@57CID<*A4/)G:)ID0IJGKIDIDGEH8<+==FLAEGCKEFEDD? XC:i:98 MD:Z:16A11A5T9A13A6A16A15 RG:Z:ERR229775 AM:i:29 NM:i:7 SM:i:29 MQ:i:29 XT:A:M BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.70199275 147 17 711 29 46S55M = 391 -374 CAGACAAATGAAACTCAAACAAGTTCCCCCGTGTTAAAGAAAACGAACTCACAGGGCAGCACACTATCTGACTGTTTCATGGGAAAGTCTGGAAGCGGAAA ##############################################CC<+2:::)HD@(8<6C?A;?>=>,'7(>@3>6><=<1;+7:8>A4@9%.*<07* XC:i:56 MD:Z:12A35A3C2 RG:Z:ERR229775 AM:i:29 NM:i:3 SM:i:29 MQ:i:29 XT:A:M BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.93698964 147 17 735 60 101M = 499 -336 ACTGTTTCATGGGAAAGTCTGGAAACGGCAACACCATTGAGACAGAAAACAGGTGAGTGGTTGCCTGGGGCCAGGGAACTTTCTGGGGTCATACTCTCTAT AEHFGJG:@GHHIHFI@;>JHHEEH@IJJCKJFJJKMJJIIJJHIJGI=HFHGJKLIEFFKICDIDKBIKE@IIIJHGIKKHIGIDIFIG<IFKMJMBGKDFFJF@CGBBIGINHJEJI?FFBDILDLDDILIFGA7)?EEHLIMIHFIFHHHIFDFJD X0:i:1 X1:i:0 MD:Z:83T5G11 RG:Z:ERR229775 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@F +ERR229775.92236775 81 17 758 37 101M * 0 0 AACGGCAACACCATTGAGACAGAAAACAGGTGAGTGGTTGCCTGGGGCCAGGGAACTTTCTGGGGTCATACTCTCTATGTTGATTCTGGTGGTGGAAACAA A?>FGG@BDCFFJIJIMIKIMFFIKJILIIKJNIKJILJMJKKMLMLMLMJIIJFINMLFJGLKJKJJHIKKJLJHIJJLIIHDJKIJGIEFGFGHGHDFB X0:i:1 X1:i:0 MD:Z:70T5G24 RG:Z:ERR229775 AM:i:37 NM:i:2 SM:i:37 XT:A:U BQ:Z:CA@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@AA +ERR229775.17900575 147 17 760 60 101M = 527 -333 CGGCAACACCATTGAGACAGAAAACAGGTGAGTGGTTGCCTGGGGCCAGGGAACTTTCTGGGGTCATACTCTCTATGTTGATTCTGGTGGTGGAAACAAGA +EGGCFD>EEFAJIIIJHMHEEJJHKIHJIMDCHHKKJJJJMMEEEKMKIBHBLKLKCIJKLIJGHCAGIFDDF>HFHFIHECEGDF?GEB?EFCFEEIEB X0:i:1 X1:i:0 MD:Z:68T5G26 RG:Z:ERR229775 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.83749675 83 17 783 60 101M = 553 -330 ACAGGTGAGTGGTTGCCTGGGGCCAGGGAACTTTCTGGGGTCATACTCTCTATGTTGATTCTGGTGGTGGAAACAAGACTGTCCCAGCCTGGGTGATACAG EEICDIHLCGFDCHH>DFHFKGDCNEKJJLHLLG;KIIIDLJEEJD@IC=D=0GMFLIJLCJHHCHFEHIIHHJHIHDFIHKHGHKH>HHAFDE=GEF=H: X0:i:1 X1:i:0 MD:Z:45T5G49 RG:Z:ERR229775 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.63559677 147 17 833 60 101M = 594 -339 TATGTTGATTCTGGTGGTGGAAACAAGACTGTCCCAGCCTGGGTGATACAGCGAGACCCCATCTCTACCAAAAAATTAAAAATTAGCTGGGCATGGTGGTG FDHFHIHEF@FDD;5AC::ELBGCBHE3DKIHEHMFAHLE=BACIGH>IFB7FEHBC=G>KHFCHIFFGJDHEFFBB@BACFCCD@ X0:i:1 X1:i:0 MD:Z:1G99 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:[YZA@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.19017039 147 17 839 60 11S90M = 560 -368 CTCTCTATGTTGATTCTGGTGGTGGAAACAAGACTGTCCCAGCCTGGGTGATACAGCGAGACCCCATCTCTACCAAAAAATTAAAAATTAGCTGGGCATGG ############GJE:GEE?9)D<=B?09>.>/1?ACBCBIJIA@@?5FEEC9HL<<8?7,B?@@@BGHGC9BHIHGI:GG@BHHCFGGJ<3ED;;CDAB@ X0:i:1 X1:i:0 XC:i:90 MD:Z:90 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.98760722 163 17 840 60 101M = 1103 363 ATTCTGGTGGTGGAAACAAGACTGTCCCAGCCTGGGTGATACAGCGAGACCCCATCTCTACCAAAAAATTAAAAATTAGCTGGGCATGGTGGTGCATGCCT CBG@;DACF=HDJFJJCMJH@JGIKKIFDFFFHHEGEDHKHGCGJJICAB=?AIIIGGEG X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C +ERR229775.516742 163 17 845 60 101M = 1152 407 GGTGGTGGAAACAAGACTGTCCCAGCCTGGGTGATACAGCGAGACCCCATCTCTACCAAAAAATTAAAAATTAGCTGGGCATGGTGGTGCATGCCTGTAGT A;>HF=GAIHGGH?FIEHGE9EFCIEA=@@ X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@CBFH +ERR229775.55719080 99 17 994 60 101M = 1282 388 TCAAGGCTGCAATGAGCTATGATTGCGCCACTGCACTTTGGCCTGGACAACAGAGCAAAACCCTGTCTCTAAAAAAAGAAAAGAAAAGAAAAACTCACTGG BFHIGFHLHHEKIIJKKKHIJKIKILAKLJJLJKJJMKKLJLMMJMLKKNKKMLKLKNNNKMMMKIKMJNKMMMNGHHJFHHIKHIIIKHIHCGMGHDIEC X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A +ERR229775.77830097 163 17 1036 60 101M = 1255 319 CTGGACAACAGAGCAAAACCCTGTCTCTAAAAAAAGAAAAGAAAAGAAAAACTCACTGGATATGAATGATACAGGTTGAGGATCCATTATCTGAAATGCTT BIEBGCCHCBCHHH,=FICDJKHCGDGJHJJKHFIIJKLLIKLGLGKLMMDHLJJDLFIKIDIDIKIGJIFHHGFHEHJH?JIIFJFFIIFLIJHGHGGIB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D@ +ERR229775.3695912 99 17 1042 60 101M = 1118 176 AACAGAGCAAAACCCTGTCTCTAAAAAAAGAAAAGAAAAGAAAAACTCACTGGATATGAATGATACAGGTTGAGGATCCATTATCTGAAATGCTTGGACCA BHEGGIHHHKIKGJKLJIKLLLIMMMMMMJKLMMKLMMNKLNMNNKLLJJNLMLKJKJLMKJLJJHKJHHHHLHFJIHHHIKIKINJKIHJIIMJGEHDED X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@C@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.54641833 99 17 1042 60 101M = 1321 379 AACAGAGCAAAACCCTGTCTCTAAAAAAAGAAAAGAAAAGAAAAACTCACTGGATATGAATGATACAGGTTGAGGATCCATTATCTGAAATGCTTGGACCA BHEGGIGGGKIKGGKKHAHLJLIMMMMMLJKLMMKKMMMFLLMNMJNMKJMJMLKJKJLMKJLJJHKJHGHHJHFJIJHHIKIKINJKIHJIIMJGEHDEF X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@C@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B +ERR229775.90795085 163 17 1066 60 101M = 1297 331 AAAAAGAAAAGAAAAGAAAAACTCACTGGATATGAATGATACAGGTTGAGGATCCATTATCTGAAATGCTTGGACCAGATGTTTTGAATTTTGGATTTTTT BGHGHEDHGDCHJGJHIJI?JGJIHHKIKIGHHIKLIFKIIJIHL=HIKJCIGLLHIHKJMLKIEBEHJMLJDMIJKJMIKLDHKCJJGFDHHGGGEFFCB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:JOOLJ@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@BCEGEE +ERR229775.51118640 99 17 1069 60 101M = 1370 401 AAGAAAAGAAAAGAAAAACTCACTGGATATGAATGATACAGGTTGAGGATCCATTATCTGAAATGCTTGGACCAGATGTTTTGAATTTTGGATTTTTTCAT BHFHIJJHJKIKJJKKLKHLLJJMKLKJJJKLMJKLJJJKMMFJGKKMLJMMKKLJKMNLMNNKLMNKLKLKMKLMLLIGLLIKNKKLKJCKHFEEFCFGE X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:EJ@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B +ERR229775.57580585 163 17 1077 60 101M = 1316 339 AAAAGAAAAACTCACTGGATATGAATGATACAGGTTGAGGATCCATTATCTGAAATGCTTGGACCAGATGTTTTGAATTTTGGATTTTTTCATATTTTGTA BGHGEEE@G>9JHEGHGIFFHHHJKHHIFBAIIFGHHIJKHIJKIIKJIKGJKMLJKKNKKBLDLJKLJLKKJKHLIKLKLKIKLFLKLFIJJEIJGHFDE X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:CFFB@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@G +ERR229775.82642257 163 17 1081 60 101M = 1336 355 GAAAAACTCACTGGATATGAATGATACAGGTTGAGGATCCATTATCTGAAATGCTTGGACCAGATGTTTTGAATTTTGGATTTTTTCATATTTTGTAATCT BGHGHH@JEB@JGHHEGGGHJHBJHHIFIICIA>HDJIKJIIJIILLKJLGJJLMJJGLJLGKIHJ=JJKLLMJKKLKFMKLLLLFIJKIKKKKHGGFGGJ X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@L +ERR229775.30538656 163 17 1087 60 101M = 1321 334 CTCACTGTATATGAATGATACAGGTTGAGGATCCATTATCTGAAATGCTTGGACCAGATGTTTTGAATTTTGGATTTTTTCATATTTTGTAATCTTTGCAG A?BHJEKFGG??IKKKAEIKJJLLKLLEHKLKIHIJIILEGGEG? X0:i:1 X1:i:0 MD:Z:7G93 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.87113255 99 17 1096 60 101M = 1361 365 TATGAATGATACAGGTTGAGGATCCATTATCTGAAATGCTTGGACCAGATGTTTTGAATTTTGGATTTTTTCATATTTTGTAATCTTTGCAGTATATTTAC ?EFGGFHHJHFGIAHIIFKLLKJKLJJKIJKMKLMMJJMNKJMEHHFIEDIKLKLGLLKLLLLKLKJHKJJKKHKFIKD;JCGEIGDIIDK=4CEDEFAEB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D +ERR229775.98760722 83 17 1103 60 101M = 840 -363 GATACAGGTTGAGGATCCATTATCTGGAATGCTTGGACCAGATGTTTTGAATTTTGGATTTTTTCATATTTTGTAATCTTTGCAGTATATTTACCAGTTCA EFFFGLHGHJLNKLKJGLLNLILLLIAKKKJLNKJHJMJNIJKDNNNKLLKNNNJMMJMNNNNLKJIJMMMJIJKJKLMLJJEFHHHCIJAGFFHLDIHE? X0:i:1 X1:i:0 MD:Z:26A74 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.37017046 99 17 1113 60 101M = 1339 326 GAGGATCCATTATCTGAAATGCTTGGACCAGATGTTTTGAATTTTGGATTTTTTCATATTTTGTAATCTTTGCAGTATATTTACCAGTTCAGCATCCCTAA BHDCIGGFIGCGIGKJKIKIJKLIKLKILJKKJFHJKKILJJKKLLMHJJKKLLMIJJKLLLJKJMKMNLLIJKLKKLDFLLKAFHDIIIJHKLGGFFJED X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B +ERR229775.3695912 147 17 1118 60 101M = 1042 -176 TCCATTATCTGAAATGCTTGGACCAGATGTTTTGAATTTTGGATTTTTTCATATTTTGTAATCTTTGCAGTATATTTACCAGTTCAGCATCCCTAACTCAA GDFGGHIJILLFHHMIIMLJKLIJNKKKIMNNKKKKMKMILMJLMMMMLIEIJMLJJIIJIKKLLIKIKIBGHHKJHGEIKFIIHHIGGHBAEFCDEEEE@ X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:B@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@GE +ERR229775.17531023 163 17 1121 60 101M = 1381 360 ATTATCTGAAATGCTTGGACCAGATGTTTTGAATTTTGGATTTTTTCATATTTTGTAATCTTTGCAGTATATTTACCAGTTCAGCATCCCTAACTCAAAAA BEEEDE@EFDEFGFI>GBCBJHFGGIBGFFEJIFJJJJKEFJJJJJKJIHEJKKIEGHJMMKKHGJHFIKJIKKJHJKKKIHJKKLJKHILGMGMHHIEEE X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@CGDFG +ERR229775.516742 83 17 1152 60 101M = 845 -407 AATTTTGGATTTTTTCATATTTTGTAATCTTTGCAGTATATTTACCAGTTCAGCATCCCTAACTCAAAAATTAAAAAATCTGAAATCCCAAACGCGCCAAT 7?ABDGED>DDDDJE?FB9DDCEA.=<>AD=/AEG6ABA8FD>2CGF@GFBJ?>5*G>59@.<*4JKIB;D*)JJIIBHA:8GC>=E4;H7C>F?GCEDE? X0:i:1 X1:i:0 MD:Z:72C28 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.36576640 83 17 1160 60 101M = 937 -323 ATTTTTTCATATTTTGTAATCTTTGCAGTATATTTACCAGTTCAGCATCCCTAACTCAAAAATTCAAAAATCTGAAATCCCAAACGCGCCAATAAGCATTC ADEFFKKIJIIHIIJGJIHIIFKJJINIHJJJMLHGHJLIMHGLJIGEFJKGFDKGCLKLLKMLHKKKKJLJGIKJIKLKJJIGBKAJHIGHHHLHGGHGB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D +ERR229775.6073289 83 17 1160 60 101M = 857 -403 ATTTTTTCATATTTTGTAATCTTTGCAGTATATTTACCAGTTCAGCATCCCTAACTCAAAAATTCAAAAATCTGAAATCCCAAACGCGCCAATAAGCATTC <@AFFKKIJIJHIIJGIIJJHFHKJHNIJKJHBEF@HGKHMLJLJJJLMJKIJGKGHLKLKJLLHKKKJIKJJLKJIKLKJJIGBKAFEIEHGHLHGGHHB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D +ERR229775.78971137 163 17 1189 60 101M = 1464 375 ATATTTACCAGTTCAGCATCCCTAACTCAAAAATTCAAAAATCTGAAATCCCAAACGCGCCAATAAGCATTCCCTTTGAGCGTCATGTCGGTGCTTGGAAT BBFEFFBCCB@GHHGHHGDHJJJHIGKIHGJLJHJJILLLLILJGKLMIKDFHLKHAE;@HGMGILHFIJIIFGLJJHBCHAGEGIIKIAG>CEMEGEHHD X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A +ERR229775.87728427 99 17 1242 60 101M = 1483 341 AACGCGCCAATAAGCATTCCCTTTGAGCGTCATGTCGGTGCTTGGAATGTTTGGGGTTTTGGATTTACAGCTTTGGGACGCTCAACCTGTACCTCAATAAA BHE>G?HFHKGIKKKIIIKKLLJKKKHKCEJJJJEJ?JEBDMJJMABJJIJKLJJJFCDCGDHGCCHEHGHLEEHFGHC;IMIJHGINIIIGIMHIIGGD@ X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:DJ@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@BB@ +ERR229775.77830097 83 17 1255 60 101M = 1036 -319 GCATTCCCTTTGAGCGTCATGTCGGTGCTTGGAATGTTTGGGGTTTTGGATTTACAGCTTTGGGACGCTCAACCTGTACCTCAATAAACCTGATTTTAAAA EEFFIFFIHHGINJAGKIJJGHAIJGKKMKJLKKKINMJMMLKNNNKMMKNMJJLNMMMNKMHJEALKKFJJJLJJIIILKJJHIIIEHIFHHJJJGGFFB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@IKMJ +ERR229775.55719080 147 17 1282 60 101M = 994 -388 CTTGGAATGTTTGGGGTTTTGGATTTACAGCTTTGGGACGCTCAACCTGTACCTCAATAAACCTGATTTTAAAAAAGTTTGGGGGCATTCCCCTAAGCCCG ?EIHGEHF@HCJHEFEIHEGGGHIGHHHKG>BGJDEFDBGJKDCEJKJHJELJJIJIGHF@KKIKILKKHHHIIIKGJJHJHEFDGLJJMJLLKIIJLMLJMJJMNKLLJLKLKLJNNNNKKHKKLJJJHDHGDGJGGLHGHJIHAGHJGIHAGKIHGJII@FFCCCE X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@G +ERR229775.57580585 83 17 1316 60 101M = 1077 -339 GGGACGCTCAACCTGTACCTCAATAAACCTGATTTTAAAAAAGTTTGGGGGGATTCCCCTAAGCCCGCCACCCGGAGACAGCGGATTTCCTTAGTTACTTA BEDG?HHKHIJGIKHFHGHKFDIJE?HFHIGJFFFFCCCCCKDEEGFFFFFFFEHDDDFFCJEJLCJIHGLLCLLMKIILK@KKHLKJHIIHKFJHHGHFB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:AC@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.30538656 83 17 1321 60 101M = 1087 -334 GCTCAACCTGTACCTCAATAAACCTGATTTTAAAAAAGTTTGGGGGGATTCCCCTAAGCCCGCCACCCGGAGACAGCGGATTTCCTTAGTTACTTACTATG EEHFDIFIJHIHFFCIFIIIFDGIKJJGGGGDDDDCJDECGEDEFFGECGDDDFGBCACJBGIIEJLCLKMIJKLLBLIILLKKIKHKGKFGIEGDGEFI? X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.54641833 147 17 1321 60 101M = 1042 -379 GCTCAACCTGTACCTCAATAAACCTGATTTTAAAAAAGTTTGGGGGGATTCCCCTAAGCCCGCCACCCGGAGACAGCGGATTTCCTTAGTTACTTACTATG FFHGEHEIJDFGBHKIHHGC<4FHIHHFFFF?BDBEI>G>GDCADCDDDI>AAEE@GAAD>FEB@HG8EGHIIIKHAJIHKEFGHEGGEHB;E@BDEEED@ X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.29727862 163 17 1327 60 35M66S = 1641 363 CCTGTACCTCAATAAACCTGATTTTAAAAAAGTTTGGGGGGATTCCCCTAAGCCCGCCACCGGGAGACAGCGGATTTCCTTAGTTACTTACTATGCTCCTT 7==;A97.8+7HA;IE:88;9EEFH8>;?E####################################################################### X0:i:1 X1:i:0 XC:i:35 MD:Z:35 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.82642257 83 17 1336 60 101M = 1081 -355 CAATAAACCTGATTTTAAAAAAGTTTGGGGGGATTCCCCTAAGCCCGCCACCCGGAGACAGCGGATTTCCTTAGTTACTTACTATGCTCCTTGGCCATTTC DBEFFGGGIJIKIIIIFFFFFKFHHGHGGGGHD?HEDDFFCKGDGBMJIFJC@MLNMKJLLBMMJMMLLMMJMJLIJLLIILIGIJKJHIIHGHFHGDEGA X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.37017046 147 17 1339 60 101M = 1113 -326 TAAACCTGATTTTAAAAAAGTTTGGGGGGATCCCCCTAAGCCCGCCACCCGGAGACAGCGGATTTCCTTAGTTACTTACTATGCTCCTTGGCCATTTCTCT :DCCDCJFIJHHF9FFHHMFGCFGGEDEC94#455D@=I?7BADBJJIJBCHMJJDMH?HGDLKJAHEHKA@>B=HDBIGHAEHH8ADDF<8DFEHGEGB@ X0:i:1 X1:i:0 MD:Z:31T69 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.87113255 147 17 1361 60 101M = 1096 -365 TGGGGGGATTCCCCTAAGCCCGCCCCCCGGAGACAGCGGATTTCCTTAGTTACTTACTATGCTCCTTGGCCATTTCTCTAGGTATTGGTATATTGTGTATG FEFFGGHDCHCC;HIF?15;7A:4#FD>JKG@DGMKBFLFKLKAJ@AMEE9BEBB:GFB?CIEHGJA<>DDH=BJEJIBFGJAF:DGDMIIMJJCKLLILLILKHIHKKKIJKHHFDFHKHIGHHFFJGEGFIHBBEF@FEEGDB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.48996859 99 17 1381 60 98M3S = 1659 345 CGCCACCCGGAGACAGCGGATTTCCTTAGTTACTTACTATGCTCCTTGGCCATTTCTCTAGGTATTGGTATATTGTGTCTGCTGTGAACTGTCCTTGGCCT A5FEFEGF?EHHIEIIH8HIIJJIHLJIHGIJHMJJJNA:FAIHGML;0GEDGILGHKHGKHHIKINJKLIJGGFFFF8FFLJJIFEGHLKJGGKMLILLLJKKILKIIILEKHFJJIGEE? X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C@ +ERR229775.87728427 147 17 1483 60 101M = 1242 -341 TTTGGTGACGGGTGAGGAGCAGGGACAGAAGGGTCCTGCGTGCCCTGCCTTCACAAGCCCCTGGAAGGAAAGTTGTTTTGGGATCTCTGCACCCTCAGCCT :=;FCD?1/EECJIGHCF>AAFGCIHKEA=BDAF<:EB>JFJIDBHHCHAD>+#AFDEIE?B@ X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.15144424 163 17 1542 60 101M = 1799 357 CCTGGAAGGAAAGTTGTTTTGGGATCTCTGCACCCTCAGCCTGGACAACTTGTGCCCATCTGGTGACCCCTCACTCAGCCACCAGACTTCCACGACAGGCT BDIECGEFDCEIHBGCGHGGGJEGHBIFHDJIGHJKJIJJKLH?K@JKFJEJIHILMFJMMHB;>IHIIIMIJCKKIFJHGFHJDHGMFIIJG>JFHBDDF X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:EF@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A +ERR229775.83025798 147 17 1590 60 101M = 1304 -386 CTTGTGCCCATCTGGTGACCCCTCACCCAGCCACCAGACTTCCACGACAGGCTCCAGCCTCGGCACCTTCAGCCATGGACAGTTCCGCCAGCGTTGCCCTC CA;4I?C?9HGCJEBD<08@2J<+=@=DB9CD@ X0:i:1 X1:i:0 MD:Z:26T74 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.29727862 83 17 1641 60 51S50M = 1327 -363 CTTGTGCCCATCTGGTGACCCCTCGCTCAGCCCCCAGACTTCCACGACAGGCTCCAGCCTCGGCACCTTCAGCCATGGACAGTTCCGCCAGCGTTGCCCTC ####################################################E==>=55;,C:65/9:=5J=C>FF@=GBJCB?5"D1?L;1=EHG;=BA0 X0:i:1 X1:i:0 XC:i:50 MD:Z:50 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.107364540 99 17 1651 29 101M = 1920 369 GGCACCTTCAGCCACGGACAGTTCCGCCAGCGTTGCCCTCTGTTCTGCTGTTTTCTCTACCAGAAGTGCCCTTCCCTCCTCACCTGACCACTCTGGGGAAA ?CGGDFL?FHCGFFIAKJIIJGIEHALLJJKGCHGEIEELFIFHMGFGIJDFMFKGIJCMEKHFEAHDF X0:i:1 X1:i:0 MD:Z:14T86 RG:Z:ERR229775 AM:i:29 NM:i:1 SM:i:29 MQ:i:29 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@CBF +ERR229775.48996859 147 17 1659 60 33S68M = 1381 -345 GACTTCCCCGACAGCCCCCAGCCTCGGCACCTTCAGCCACGGACAGTTCCGCCGGCGTTGCCCACTGTTCTGCTGTTTTCTCTACCAGAAGTGCCCTTCCC ##################################G=:?F3CCE>D:8=64'#)'I<=):7>HIB@=A:CE1;:C=JJHC9A:<7=BCFHCL@LHEHIEHA@ X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.69874320 163 17 1704 60 81M20S = 1920 309 TCTCTACCAGAAGTGCCCTTCCCTCCTCACCTTACCACTCTGGGGAAATCCCTCAGCACCCTCCCTGAGCATACCCTACTCCGGCACAAGCCCAACCTGCA 74J?@C:D@-=C;696/*=;DD8+@*@7C94='04*65:A@860;+9H##################### X0:i:1 X1:i:0 XC:i:81 MD:Z:32G48 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.51562629 147 17 1727 60 101M = 1445 -382 TCCTCACCTGACCACTCTGGGGAAATCCCTCAGCACCCTCCCTGAGCATACCCTACTCTGGCACAAGCCCACCCTGCAAAGCCCCTGAGGCCCGCCCTGTG ADDFD?GHHEBGIGIHIJHHHHGGHGFEGHFJB;2CB?FADDEAJDDFC@8ABCE?A@BCACCB@H@<AEGG@HEG;ACBGCHFFAFF/?GFJLHILKLHIGGIJM:CECFEIHLBFIDJEHEHILAHB5CFG@FGGLHHHGI3?FFILIHHMHGGKC6C X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:GAA@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.2494821 99 17 1749 60 101M = 2024 375 AAATCCCTCAGCACCCTCCCTGAGCATACCCTACTCTGGCACAAGCCCACCCTGCAAAGCCCCTGAGGCCCGCCCTGTGGCGTCTCTCCCTCCCTTGCTGT AHHGFFFLHHGIIHKKHHJKLJKLKJJJJLLMJJJJMJCLJJJNFJLMKKMMNLMKLNMMLMIMHKJHJGG@ X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@FC@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.15144424 83 17 1799 60 101M = 1542 -357 CCTGCAAAGCCCCTGAGGCCCGCCCTGTGGCGTCTCTCCCTCCCTTGCTGTCAGGACAGTGGTCCTGGCCTCCGGGGCTCACGGAGCCGCCCTGTGCCATG @BGGGGB8D@HEHKEJFGGGACGCGKFGGF?EGCCCCDDCGEEFEIGFHDIFJEGGFJDFEBHCEFGEGJKE>LLLKJKII@KKLKKAIHFIHFHHEGFHB X0:i:1 X1:i:0 MD:Z:70A27G2 RG:Z:ERR229775 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:BD@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@Z\V +ERR229775.97978507 163 17 1893 60 101M = 2135 342 TGCCGTGTACCTCTGAGCCCTCTGCACAGTGCCTTCTGCTTGCCTGTGGCTTTGAGAAGAAACCCCTTCTGGTTATACATAAGACAGCCAGAGAAGGGAGT BEFCHHGIEFJDFKHGBGCFF7CAD X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D +ERR229775.107364540 147 17 1920 29 101M = 1651 -369 AGTGCCTTCTGCTTGCCTGCGGCTTTGACAAGAACCCGCTTCTGGTTATACATAAGACAGCCAGAGTAGGTAGTTGCCCAGGGTGGCACACTACGTTGCTG <@DE96DJHGG>8CG@:?4$=@*IBB@41AEC<=3+#(B<@6F=287JIG?C8(A@BCIH>MLJFH?C;CJIFGCGDIBIJHDCJCEFFHHIHD?ALEC5CHMD38CECLGCE?45HLCE;BEGFHGJ<=C? X0:i:1 X1:i:0 XC:i:94 MD:Z:94 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.43533499 83 17 1932 60 101M = 1693 -339 TTGCCTGTGGCTTTGAGAAGAAACCCCTTCTGGTTATACATAAGACAGCCAGAGAAGGGAGTTGCCCAGGGTGGCACAGCACGTTGCTGCCAGTTACTGCC 2D>ADFGGIIHFIKILIFLDB51FCBHGGCKJILFIKKJKKJMIHJMLKJMLMJHLIGIMJMKJGJHGKKIJHFIIFLDHG@HIFIGGGH?KCEGHGGF?? X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.22929983 83 17 1950 60 101M = 1693 -357 AGAAACCCCTTCTGGTTATACATAAGACAGCCAGAGAAGGGAGTTGCCCAGGGTGGCACAGCACGTTGCTGCCAGTTACTGCCATTTTCACAGGCATGAAA HEA>CFFGIHKIKIGMKLKJIFKKMEIKLJHKNKMKKNMMLNKNKMJCLMMMJJMMLJKMLHIAKMJLLJKLKMJLJILJJKHHLLKJIIFKGHHHGFFFB X0:i:1 X1:i:0 MD:Z:91G9 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:C@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ADB +ERR229775.66105707 83 17 1971 60 101M = 1746 -325 ATAAGACAGCCAGAGAAGGGAGTTGCCCAGGGTGGCACAGCACGTTGCTGCCAGTTACTGCCATTTTCACAGGCATGAAATGGAGATAACAACAGGAGCGA EFCIGFCMICINIMIGJIKKNBJKIHIKMJJKKLJIFINLJKCKMKLMKJJGMJMIGKJHFHIMMLKJIIMLKJIIKKJIIKKKKHHDIIGIHLFGKF:FB X0:i:1 X1:i:0 MD:Z:70G30 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.105154648 163 17 1981 60 101M = 2189 308 CAGAGAAGGGAGTTGCCCAGGGTGGCACAGCACGTTGCTGCCAGTTACTGCCATTTTCACAGGCATGAAATGGAGATAACAACAGGAGCGACCGCACAGGC @DCE:EEFD<=H?>>?FF==CCB@1:C=FFGHG;<=?HKICHBC?4AFEE:HEC5AJ3B;H?A>6BCEB85 X0:i:1 X1:i:0 MD:Z:60G40 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.52172354 163 17 1982 60 79M22S = 2196 314 AGAGAAGGGAGTTGCCCAGGGTGGCACAGCACGTTGCTGCCAGTTACTGCCATTTTCACAGGCATGAAATGGAGATAAGAACAGGAGCGACCGCACAGGCT A@?:E>31<61E<;88BG,%/C8/4BAG4;BA1AG92D;D?C9<=)?>;C?BDF+9D+0>>0;DGJG####################### X0:i:1 X1:i:0 XC:i:79 MD:Z:59G18C0 RG:Z:ERR229775 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.39805220 163 17 2022 60 82M19S = 2315 385 CAGTTACTGCCATTTTCACAGGCATGAAATGGAGATAACAACAGGAGCGACCGCACAGGCTGCTGAGCGCGTCACACGCAGCCATCGCGCAGCTCAGGGAT @94EAE@J>:3GGEGCGD9=ECACGGHHHE;HHB?DFC1E:AA@AJJE=@C6=43>@CI?8DBC#################### X0:i:1 X1:i:0 XC:i:82 MD:Z:19G62 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.57143597 163 17 2024 60 101M = 2298 374 GTTACTGCCATTTTCACAGGCATGAAATGGAGATAACAACAGGAGCGACCGCACAGGCTGCTGAGCGCGTCACACGCAGCCATCGCGCAGCTCAGGGATAT @DAECIBEC@AGHEICGGIHJHGIEHAGHEDGICFLHILJCJ8FDE>KDD3;C?CJEDHFGEGFCF=F<>>EBIE@DECD?>DB9BECBHCJDADD;AE@;>C>HLEFCDH>IILJ@G6IJGG:AEJACCEEB@ X0:i:1 X1:i:0 MD:Z:17G83 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B +ERR229775.11251161 163 17 2065 60 101M = 2333 368 GGAGCGACCGCGCAGGCTGCTGAGCGCGTCACACGCAGCCATCGCGCAGCTCAGGGATATTACGTGTAACTCGACATGTCAGCGATTGTCACAGGCACTGC @3B"2=<"5?9=JGBBB'=:@;DFC=?698AFCD4;74C@EBD7IBFHH8AD@G+-3HGHFHF>IIKJKIHKBKBLJLLLLJLLJKJJJKJJCHJKJLHMMBLHJJIGIJGI>HFCFGJKEHGFHIFMIJMIDMIIMIHGHADFFIHKIGHEDB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D +ERR229775.18301321 163 17 2092 60 101M = 2301 307 GTCACACGCAGCCATCGCGCAGCTCAGGGATATTACGTGTAACTCGACATGTCAGCGATTGTCACAGGCACTGCTACTCCTGGGGTTTTCCATCAAACCCT AFEECE789<',AD@GF@BG?>H<4F7GBIE=@>FCF;=;CEBFE>D=A=AAJGHKH;DDFKHG?C02BAIHG@@FEAA3=6 X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.97978507 83 17 2135 60 101M = 1893 -342 TCGACATGTCAGCGATTGTCACAGGCACTGCTACTCCTGGGGTTTTCCATCAAACCCTCAAGAGCTGGGCCTGGGGTCAACTTCCAGCCTGGGGAAACTGG E=FGGHIGKINJBIJIJGMIJFMIJHIHJHHIGJLHJJIILFNNNLMLKLJKJGMMMLKKMLMKKJLLLLLJLLLJKKJILLKKJLKJJIEGGGHHHGHEB X0:i:1 X1:i:0 MD:Z:85G15 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@GG +ERR229775.15256528 147 17 2147 60 2S99M = 1898 -347 AGCGATTGTCACAGGCACTGCTGCTCCTGGGGTTTTCCATCAAACCCTCAAGAGCTGGGCCTGGGGTCAACTTCCAGCCTGGGGAAACTGGGGCAAGTATC ###E?E<9G=8IMIIFGED<9;(BABBB;8;99?ABIGDCHJD?<:;C7FBEE3EBHDG9@CCKGHH@??D@;HFG>1EEF=BCDAG9631,D9DE@7 X0:i:1 X1:i:0 XC:i:99 MD:Z:20A52G25 RG:Z:ERR229775 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.75821297 145 17 2155 37 101M * 0 0 ACAGGCACTGCTACTCCTGGGGTTTTCCATCAAACCCTCAAGAGCTGGGCCTGGGGTCAACTTCCAGCCTGGGGAAACTGGGGCAAGTATCACCAGAGATG EFKFHHIIJIIH@IKGIJHHHFLLLJFGJKHJHEIIMJJKMLNKKIKKMJGELKLJKGHGLLKIJLKJKIJIKKIHHJFJJHHHHHGFGH<;DEFEIEEG@ X0:i:1 X1:i:0 MD:Z:65G35 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.105154648 83 17 2189 60 101M = 1981 -308 CCCTCAAGAGCTGGGCCTGGGGTCAACTTCCAGCCTGGGGAAACTGGGGCAAGTATCACCAGAGATGAGCTTTATAAAAATAATGGTGCTAGCTGGGCATG ?BEHFGKILIHGFFGDFGEGFBHEGKHNLFJNLKKKLILKKIKKKLIFJCKJJJJLJKJJMLMJIIJJICLLJJIIJIIEHJGGJHIFHIIHDHFFFEFH? X0:i:1 X1:i:0 MD:Z:31G69 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A +ERR229775.52172354 83 17 2196 60 101M = 1982 -314 GAGCTGGGCCTGGGGTCAACTTCCAGCCTGGGGAAACTGGGGCAAGTATCACCAGAGATGAGCTTTATAAAAATAATGGTGCTAGCTGGGCATGGTGGCTT EHCBDDB?7=E=DBAKCDGLHHEIMICHKJHAKKKK>CDJIJIKMGFJKIFFJMLMHIIEMJKMDHIJKJKJJJIIJKIJJJHJHFHGFIJGADHICGHJIJKDIIFIJCGEDGBD X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:EJ@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@F +ERR229775.59500924 99 17 2276 60 101M = 2490 314 GCTAGCTGGGCATGGTGGCTTGCACCTGTAATCCCAGCACTTTGGGAGGCCGAGCTAGGAGGATCGTTTGAGTCCAGCAGTTTGAGACCAGCCTGGCCAAT &HIEGHLHGHFIHEKIHKJLJILJJLLKIIMJLLLJMJIHMKKJJMGFJJLCLIJNJKJLJGHGJ>G@@GJGHIHKHJJFIFKIKIKGIJIIIMHAEFGDD X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.57143597 83 17 2298 60 101M = 2024 -374 CACCTGTAATCCCAGCACTTTGGGAGGCCGAGCTAGGAGGATCGTTTGAGTCCAGCAGTTTGAGACCAGCCTGGCCAATACGGCAAAACCCAGTCTCTACA ?EDFHFHFHHHEFJJFIHDEJFHHMEIF@KOJJJNJKMJMKL?JNMKLNKLMLMJJMJMMKJLCBLJILJLJLKIIKJII@JJF?JIFHEFKFJHIGGGFB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D +ERR229775.18301321 83 17 2301 60 2S99M = 2092 -307 ACCTGTAATCCCAGCCCTTTGGGAGGCCGAGCTAGGAGGATCGTTTGAGTCCAGCAGTTTGAGCCCAGCCTGGCCAATACGGCAAAACCCAGTCTCTACAA ###GAB7.BC><:*5'=GG@A:?H@A8,@B77FE-EIEEEHBDBKJDH=IACICBGGLLJHH'%/HLJCHICICFADHA?E?>:B?I:FG=EI:@@=ADC? X0:i:1 X1:i:0 XC:i:99 MD:Z:13A47A37 RG:Z:ERR229775 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ED +ERR229775.39805220 83 17 2315 60 8S93M = 2022 -385 TCCCAGCACTTTGGGAGGCCGAGCTAGGAGGATCGTTTGAGTCCAGCAGTTTGAGACCAGCCTGGCCAATACGGCAAAACCCAGTCTCTACAAAAAATACA #########DFBIFEJB?%?I@FFIMFFGFFFD;DLMJEJ>8FGMHGHBMKHFM=/GCJFJKEKJCFJD8JAHHIJJIIIDII@AEJFGHBGHHHHFEHC? X0:i:1 X1:i:0 XC:i:93 MD:Z:93 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A +ERR229775.12020490 147 17 2330 60 101M = 2089 -341 CTAGGAGGATCGTTTGAGTCCAGCAGTTTGAGACCAGCCTGGCCAATACGGCAAAACCCAGTCTCTACAAAAAATACAAAAAACAACTAGCCAGGCGTGGT EFKFGLHIEHGFHIIDDHHCIAJGBBHDB;=+EB@ X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.11251161 83 17 2333 60 101M = 2065 -368 GGAGGATCGTTTGAGTCCAGCAGTTTGAGACCAGCCTGGCCAATACGGCAAAACCCAGTCTCTACAAAAAATACAAAAAACAACTAGCCAGGCGTGGTGGT BA,>9DHC@BEKKIKCAAGKFEGIIHDCJHEG?IIFKJDEFFIMHKIDHDFFJJJIIICEEHJJIJJIJECIKJJILEI?FHFDGEEB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.80729707 99 17 2417 29 101M = 2698 358 TAGCCAGGCGTGGTGGTGCACACCTGTAGTCCCAGCTACTCAGGAGGCTGAGGGGGAAGGACTGCTTGAGCCCAGGAGTTTGAGGCTGCTGTGAGCTGTGA :EBE?HH>CECHH;>?IDEFLDGNIJIGHG@B?AGF@ X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.101859832 99 17 2474 60 101M = 2762 388 AGGACTGCTTGAGCCCAGGAGTTTGAGGCTGCTGTGAGCTGTGATCGCATCACTGCATTCCAGCCCGGTGACAGAGTGAGTCACTGTCTCGAAAAAGAAAG ?ECGDLGFKGCKHGKKIGKGHGIIIKJEILJKLJFJ@EHGH:CHJL?HJHIJHMLLIJIEFJKIIE=HB>HGJHJIBEH>GGJHJHHFMG;H?FCHB6>CA X0:i:1 X1:i:0 MD:Z:90A10 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C +ERR229775.59500924 147 17 2490 60 101M = 2276 -314 AGGAGTTTGAGGCTGCTGTGAGCTGTGATCGCATCACTGCATTCCAGCCCGGTGACAGAGTGAGTCACTGTCTCGAAAAAGAAAGGAAGAAATAAAGAAAA IEFKEGJJIMIIDJJIJGJHMHHIHIGHI?HHJLHJJJLKJMKGJMKJI?DJJKJJMKLJIIKHJFCGIFIFJ;KIIIHKJGGJIHHIGGCB@FCIEEEEB X0:i:1 X1:i:0 MD:Z:74A26 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:D@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@CEC +ERR229775.5983641 147 17 2506 60 101M = 2267 -339 TGTGAGCTGTGATCGCATCACTGCATTCCAGCCCGGTGACAGAGTGAGTCACTGTCTCGAAAAAGAAAGGAAGAAATAAAGAAAACAAATAAAAATAATAG GDGGKHHJGGEIKAGHHKIKHKJHKMKEGNJJ?;LIKJJCJJNGJKLHKHCJHFFEK>GJJJJKFIJKIJHJIIIHHIHKJGGHGFHGGGBBEFCEFEEI@ X0:i:1 X1:i:0 MD:Z:58A42 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:B@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.52727770 163 17 2538 60 101M = 2848 395 CCGGAGACAGAGTGAGTCACTGTCTCGAAAAAGAAAGGAAGAAATAAAGCAAACAAATAAAAATAATAGTGCAGACAAAAGGCCTTGACCCATCTAGCTTT @0=>12?7?C;8I=0;9>#AH@ECA9=9=0().D=:;CKBE'450120:7+@C=E4C6E@CE5ACFI@D<@>9G=?;?E*=3HEKKJJCHKKHFHGJKLIILLGJLLLJJMMJJIMMMJJMHKKEEJGKLJKMLMKJJILKGLHJKJIIMIIIMFFIGIGGKFGE X0:i:1 X1:i:0 MD:Z:17A83 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.18618553 163 17 2570 60 101M = 2828 358 GAAAGGAAGAAATAAAGAAAACAAATAAAAATAATAGTGCAGACAAAAGGCCTTGACCCATCTAGCTTTGGCCCTCAGCATCAACCGCTAGATACGTCCCT @>DGC8=FEC>CGDIEHCACFGFKKAFHKJBDDCJ X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@E +ERR229775.83543817 99 17 2577 60 77M24S = 2821 288 AGAAATAAAGAAAACAAATAAAAATAATAGTGCAGACAAAAGGCCTTGACCCATCTAGCTTTGGCCCTCAGCATCAACCGCTAGATACGTCCCTCCCTTTC 4::A:>A>G8)>F<>ADDHDCGAJ<=JB,*EB797,>HHL@C95=/:EC=@@FC>GEJHC=479788BI96F0EKK######################### X0:i:1 X1:i:0 XC:i:77 MD:Z:77 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.66162627 99 17 2602 60 101M = 2766 264 AATAGTGCAGACAAAAGGCCTTGACCCATCTAGCTTTGGCCCTCAGCATCAACCGCTAGATACGTCCCTCCCTTTCTTCTGGGGCACAGGTCACACTCTCT ?DFGEHGFHIHGJEKKGGJJLJKKJLLIIKMIFHMJJIIJLLKJJIJKHJKMKFAJLJKLJKGBHJIFKGHHLHIJMIIGF>BCGJGKDCJIJGGFKFIEH X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@J +ERR229775.36854728 99 17 2628 60 99M2S = 2910 357 CATCTAGCTTTGGCCCTCAGCATCAACCGCTAGATACGTCCCTCCCTTTCTTCTGGGGCACAGGTCACACTCTCTTCCAGGTCTAGGATGCAGCTGAGGGG 4GFEJG@EKG=@.BEGJ+AHFCFCGLGGD/E9CGADGFH?GDKGLFIAHDJ@BHGLEFDGEE=DDGIBFB### X0:i:1 X1:i:0 XC:i:99 MD:Z:99 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B@@@ +ERR229775.80729707 147 17 2698 29 23S78M = 2417 -358 TGCTTCTGGGGCACAGGTCACACTCTCTTCCAGGTCTATGATTCAGCTGAGGGGTGCCACTCTTACCATCTAATCTGTGCGCTTATTTACTCTGCTTTAGT ########################HI<4*16J>9**D?/?:9**HC)F3A'6B3F/;1.(((>/2&-5=*;,3HA<':0+('/(;/*7.(7%;'.2C@481 XC:i:78 MD:Z:15G3G15C21C7C12 RG:Z:ERR229775 AM:i:29 NM:i:5 SM:i:29 MQ:i:29 XT:A:M BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.94440410 147 17 2716 60 101M = 2419 -397 TGCAGCTGAGGGGTGCCCCTCTTACCATCTAATCTGTGCCCTTATTTCCTCTGCTTTAGTGAGGAAGAGGCCCCTGGTCCATGAAGGGGCCTTTCAGAGAC DEFJHGD>7E>ADGG@:9HJBIEADHGGGIHJJFGA>A?99DEKGFCC=4<%DGG;@BCCEDDF### X0:i:1 X1:i:0 XC:i:99 MD:Z:99 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.45483038 99 17 2750 60 101M = 3055 353 TGTGCCCTTATTTCCTCTGCTTTAGTGAGGAAGAGGCCCCTGGTCCATGAAGGGGCCTTTCAGAGACGGGGACCCCTGAGGAGCCCCGAGCAGCAGCCGTC BFHGGFFLHHGIIJKLKKJKLJJIHIKKMLLLLLMFEKMMNLMJLLJJJKMIFCFLILKLLKMLNLICHBEJ3AFAEEKCBCDGFIF;?=CCHFFEEC83; X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.78014576 99 17 2757 60 91M10S = 2948 291 TTATTTCCTCTGCTTTAGTGAGGAAGAGGCCCCTGGTCCATGAAGGGGCCTTTCAGAGACGGGGACCCCTGAGGAGCCCCGAGCAGCAGCCGTCGTGTCTC BFGGGHGFKHIIIHIJFKHIKJLILLKLJKKMLMJLFJLJJJLNMMMMLMMKLMKMLKLJBJJFGCGFFECGHFB@HFFF/7@67?9E@F########### X0:i:1 X1:i:0 XC:i:91 MD:Z:91 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.101859832 147 17 2762 60 101M = 2474 -388 TCCTCTGCTTTAGTGAGGAAGAGGCCCCTGGTCCATGAAGGGGCCTTTCAGAGACGGGGACCCCTGAGGAGCCCCGAGCAGCAGCCGTCGTGTCTCACCCA <8=DBIGIHJGIDJIMHICFA?BGEFAG9FEGAAJ@CC?@DCFHAJ>>811?C;85FEHCBHA>@K8EE=3@<@EHB=;HI>FF?EB@FF=C5CBA@ X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.66162627 147 17 2766 60 101M = 2602 -264 CTGCTTTAGTGAGGAAGAGGCCCCTGGTCCATGAAGGGGCCTTTCAGAGACGGGGACCCCTGAGGAGCCCCGAGCAGCAGCCGTCGTGTCTCACCCAGGGT EHGCA-@LEEDGHEFLEMHB?B?@FGEIDG?CA?FC>ACD1??@;AEAGCGGAAJKGFHK=IEB?LGCEFFHDCG#:3?EBFBGDF X0:i:1 X1:i:0 MD:Z:90T10 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B +ERR229775.44852854 83 17 2817 60 101M = 2547 -370 GGGGACCCCTGAGGAGCCCCGAGCAGCAGCCGTCGTGTCTCACCCAGGGTGTCTGAAACAGATGTGGAGGTCTCGGGTGAGGCGTGGCTCAGATACAGGGA BCC?6ABEHFILIIJJGGG;IGIHMIHIHF?EH?HKHLKLKKMMLNMMJKKMMKMKLKKNLJKKKLMMLIKJLBKLJJLLLKBIIKJFKIIHHHIHKEEFB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:CBA@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.83543817 147 17 2821 60 56S45M = 2577 -288 TCTGCTTTGGTGAGGAAGAGGCCCCGGGTCCATGAAGGGGCCTTTCAGAGACGGGGGCCCCTGAGGAGCCCCGAGCAGCAGCCGTCGTGTCTCACCCAGGG #########################################################7,,/?4:@2;'B6#'01'8,2'4&8.;H29?@:+&'-13CH;-1 X0:i:1 X1:i:0 XC:i:45 MD:Z:0A44 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.18618553 83 17 2828 60 101M = 2570 -358 AGGAGCCCCGAGCAGCAGCCGTCGTGTCTCACCCAGGGTGTCTGAAACAGATGTGGAGGTCTCGGGTGAGGCGTGGCTCAGATACAGGGAGTGGCCCACAG #B7@??990GHIIMFDEICAGH?FHCD<+@FEEHHIIIJILKKLKJKLNLJKKKMLMMJKIGBKIJJMMKK>GJLKJIKLLIHEJKJJIKEHGHE@EFDK? X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.91229453 99 17 2831 60 101M = 3084 353 AGCCCCGAGCAGCAGCCGTCGTGTCTCACCCAGGGTGTCTGAAACAGATGTGGAGGTCTCGGGTGAGGCGTGGCTCAGATACAGGGAGTGGCCCACAGCTC ?CGEEF?HBGFIGFKJJABI@JIIIKKJJLKJKLLABEHLJLLMKKILJJJJFKKHGFLI=DD?BGFEG>@BBFIJKIKGIHJIG@HHHFKGEF:E7 X0:i:1 X1:i:0 XC:i:86 MD:Z:86 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.7004516 163 17 2878 60 101M = 3107 329 ATGTGGAGGTCTCGGGTGAGGCGTGGCTCAGATACAGGGAGTGGCCCACAGCTCGGCCTGTCTTTGAAAGGCCACGTGACCTGGCCCACGGCTGGCAGGTG @EEFECDFD;:JG0C=?D;AGJ?GGGJEI<=JHHHHJKIKE>CFIKLGGE?HIH6?CAF>GBKBA9GIGB?EDFE@IHGFGHIGEFFJG:@FIC@EDB?6B X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D +ERR229775.36854728 147 17 2910 60 25S76M = 2628 -357 GGTCTCGGGTGAGGCGTGGCTCAGATACAGGGAGTGGCCCACAGCTCGGCCTGTCTTTGAAAGGCCACGTGACCTGGCCCACGGCTGGCAGGTGGGACCCA ##########################HHKC9,>ABC?;DBGAH=8;;IEE<>2?HB@C>HCF7<;2G79===)C@5&=*B@86FEEHA@B9:<797DB3;@ X0:i:1 X1:i:0 XC:i:76 MD:Z:76 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.28172972 163 17 2918 60 101M = 3194 376 GTGGCCCACAGCTCGGCCTGTCTTTGAAAGGCCACGTGACCTGGCCCACGGCTGGCAGGTGGGACCCAGCTGCAGGGGGCCAGCAGCACCCACAGCAGCCA BFECEDAFC@CGJH?GIIGGHIJIIGJHHD;A;@=D@9BE>:D=BHI9;;A"99>><@>BCEEE=CFEFIBAC# X0:i:1 X1:i:0 MD:Z:78T22 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.78014576 147 17 2948 60 101M = 2757 -291 GCCACGTGACCTGGCCCACGGCTGGCAGGTGGGACCCAGCTGCAGGGGTCCAGCAGCACCCACAGCAGCCACCTGTGGCAGGGAGGAGCTTGTGGTACAGT C@AB=GIC>BDHFFG@@??HHFHGEEIGHHHFBCFFIHHDJJEFMLHJKFEFHILEF>IHGGIIHJIHHI?EKIIHJJEJJHEJIDJHHIB@ED@EFEIDB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.19870548 163 17 2964 60 101M = 3254 390 CACGGCTGGCAGGTGGGACCCAGCTGCAGGGGTCCAGCAGCACCCACAGCAGCCACCTGTGGCAGGGAGGAGCTTGTGGTACAGTGGACAGGCCCTGCCCA ADDECGIGHJHBFH:F=:<9D??FIKJIGJHCHLGIHIEABDE@CGDDFFAFA?CDE@E9B?6>4B@@FAA6E6@5*>1=B>DB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.91036639 147 17 2967 60 101M = 2776 -291 GGCTGGCAGGTGGGACCCAGCTGCAGGGGTCCAGCAGCACCCACAGCAGCCACCTGTGGCAGGGAGGAGCTTGTGGTACAGTGGACAGGCCCTGCCCAGAT 53AFE?BAHGJIHIBCCEDIGIF=GGGGHKCFKF@F=?CGLJGBKIIKGG?:IJJJJKLJKLKJLKKKIKHB@HICHBHKHFEHGFJHGFBCFE@CEIFEB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.11173812 99 17 3034 60 101M = 3333 399 AGCTTGTGGTACAGTGGACAGGCCCTGCCCAGATGGCCCCCCGCCTGCCTGTGGAAGTTGACCAGACCATTTGTCACAGCAGGTAAGACTCTGCTTTCTGG ?CFKBHGHEHFGHEIGDHHILKLLLMIIKLJJKIJIKILMMM>JIMIHIMJFCDJLG0ADIHIGCGDEHHHEHIIKHKHGJIG8GKHKGNIMIIKGDFCEA X0:i:1 X1:i:0 MD:Z:70C30 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@GF +ERR229775.45483038 147 17 3055 60 52S49M = 2750 -353 GCCCCCACAGCAGCCACCTGTGGCAGGGAGGAGCTTGTGGTACAGTGGACAGGCCCTGCCCAGATGGCCCCCCGCCTGCCTGTGGAAGTTGACCAGACCAT #####################################################A54-7=90;?5::24>EAB?DH@DE X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@FJ +ERR229775.59323675 163 17 3154 60 101M = 3389 335 TGGAATTCCTGTCCATCTGGCAGGTGGGCATTGAAACTGGTTTAAAAATGTCACACCATAGGCCGGGCACAGTGGCTCACGCCTGTAATCCCAGCCCTTTG @B?ECD9@8@GCII88GHF<9:FIIILLLLHFJEHHJJHIJGKJGI?@BJJJJKDB>DKDJC<@EEBHFLGF?EIAGEHCCD@2ABEACFHDCC#9@?###### X0:i:1 X1:i:0 XC:i:96 MD:Z:91T3T0 RG:Z:ERR229775 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.28172972 83 17 3194 60 101M = 2918 -376 TTTAAAAATGTCACACCATAGGCCGGGCACAGTGGCTCACGCCTGTAATCCCAGCCCTTTGGGAGGCCAGGGTGGGTGGATCACTTGAGGTCAGGAGTTCA BDFCHIEIJGKDHIJHIJIMHGG?IHIHJHKHJJGCGFKBMKMKJJLKLJJIIJFJMMMKMMMLMKFHLMKJJLLJIKIIKGDKLIKKIGHHKFGLDIHFB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:ABA@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D +ERR229775.453972 81 17 3215 37 2S99M * 0 0 AGGCCGGGCACAGTGGCTCACGCCTGTAATCCCAGCCCTTTGGGAGGCCAGGGTGGGTGGATCACTTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACAT ###>6FEBCCE@HGDIIHDG?GEIICHHF@FBBIGHDFFF1JMLLLJCIMLIHFLIHJIJFGE?KLJMMHCDKMLLKJLIIJEB@KJKIEGIGHFHBFEE? X0:i:1 X1:i:0 XC:i:99 MD:Z:99 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.41226651 99 17 3242 60 101M = 3478 336 TCCCAGCCCTTTGGGAGGCCAGGGTGGGTGGATCACTTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGTGAAACCCCGTCTACTAAAAATACAAA BFEEGHHFGKGIIEKJKGJHIJIIIIIIEIJKJKJIMKLLMJJJKMMGKDCIJLKLGIJFIGHCBFDHFEIHBEBCKHHDHHI?GIJJGNIHHJGDGEGDD X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@IIK +ERR229775.19870548 83 17 3254 60 101M = 2964 -390 GGGAGGCCAGGGTGGGTGGATCACTTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGTGAAACCCCGTCTACTAAAAATACAAAAATTAGCCTGGC DEFIFHBEIIIDHFIGKHGIKCHIGKKOJILHMJKNHKGJIEKIMJMJDDJIJGAKKLKKLKKMKJJLLLCIKJIIJIJJJJHDEJIIIIGKHLHFGGEFB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:CCA@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.43420834 99 17 3270 60 101M = 3494 324 TGGATCACTTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGGGAAACCCCGTCTACTAAAAATACAAAAATTAGCCTGGCGTGGGGGCGCATGCCT ?ECHGGHFKIBJHJFGHKBJJIJKJMHKIKJMLLMIJKMKNKKJLI%@GMKHILH?EEHFAJJMMMDFBDIJJJGHGJDDHLDCG;HDA#77=FIJFJIJ=JJIG;EJEFBIKKJFE:GFD8/9:*E@EE3%DJ;D2BDD@ X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:IH@G@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.94803111 163 17 3384 60 101M = 3606 322 CTTGGGAAGCTGAGGGATGAGAACTGCTTGAACCTGGGAGGCAGACGTTGCAGTGAGCTGAGATCACGCCACTGCACTCCAGCCTGGGCAACAGAGTAAGA BIEECCDHEBEGIBIGIGGHJIJHKIJKIHGLIJLJKKKLKKJKKJBIJIEJKJKKKIMJKHLEFIF@HFGDKGHIFLHHIHIHMIGBGJHGJIJHHGEFG X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B +ERR229775.91011602 83 17 3387 60 101M = 3102 -385 GGGAAGCTGAGGGATGAGAACTGCTTGAACCTGGGAGGCAGACGTTGCAGTGAGCTGAGATCACGCCACTGCACTCCAGCCTGGGCAACAGAGTAAGACTC DDFFKHHFIMIHIJKGLIHIIHKIGJIDHIJKIJKNLLLNLKCKNKMJNKKMMJKKHNMJLIFAJJHIHIIHGLKIGJKKLIKKKJIHILGKFHHLEFDGB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:CBA@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.59323675 83 17 3389 60 101M = 3154 -335 GAAGCTGAGGGATGAGAACTGCTTGAACCTGGGAGGCAGACGTTGCAGTGAGCTGAGATCACGCCACTGCACTCCAGCCTGGGCAACAGAGTAAGACTCTG A5IGFFHGIIIJKINGEGIGI;KHE?1IHHJJKMJJHMKJBKNKMJMHGIMJIJLKJHKIE?GFFJKJEFEHKEIKIEGIFHC;AFHIGL@HHLGIGHDH? X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.5896825 83 17 3415 60 101M = 3144 -371 ACCTGGGAGGCAGACGTTGCAGTGAGCTGAGATCACGCCACTGCACTCCAGCCTGGGCAACAGAGTAAGACTCTGTCTCAAAAAAAAAAAAATCACACCAT @>>ADEB1CA>FB277FJIFJ;=B18+/A098D=55?==:<>(;0=7BBH@>BEHFCBBC99?JA6@G7.A;?:7:AJGJJJJIJJIGIIGGIFHGEEFE? X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A +ERR229775.43002343 163 17 3466 29 43M58S = 3687 321 CCTGGGCAACAGAGTAAGACTCTGTCTCAAAAAAAAAAAAATAACACCATTTTGGCTTCAGAATTCATATCCTCCTGCAAGGATATATACGCGAGAAATTA 58=>BB1BB659IJHIGHHF:IFBBBHBFAG?G@HFCF;AGFDG>:AECFEEGAA X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:C@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C +ERR229775.43420834 147 17 3494 60 101M = 3270 -324 AAAAAAAAAAAAATCACACCATTTTGGCTTCAGATTGCATATCCTCCTGCAAGGATATATACGCGTGAAATTCAAGTCAATGACAAATCAGAAAAAAAAAC A9>D?@DFHHFFG9?577GHGD;IIGHGIGFKFFGDEBGACABDIB>I?G?HGKICIA9F<=>9>IGIIHJ@HIKCDDHGG<>GGCGCDJBBEFCFFEC<@ X0:i:1 X1:i:0 MD:Z:93G7 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:G@CICDGHJIEDB@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@BC@CCB@@@ +ERR229775.98041640 147 17 3494 60 46S55M = 3175 -373 CCCGCCCCGCCACCCCAGCCTGGGCAACAGGGTAAGCCTCCGTCTAAAAAAAAAAAAAATCACACCATTTTGGCTTCAGATTGCATATCCTCCTGCAAGGA ###############################################?DHGJJJHE?HD9;D;0@HD?:J7>:5>8GIIJHFGHJIHIIIINIGMIIGHFDED X0:i:1 X1:i:0 MD:Z:57G43 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.98929975 83 17 3553 60 101M = 3302 -351 TACGCGTGAAATTCAAGTCAATGACAAATCAGAAAAAAAAACATATATATACGCAAACCAGTATCCTACTGTGTGTGTCGTTTGTTGTGTTTTCGACAGCT A?>E?FIIFFJKKIFNGKIKJHIHIIEHJHLHDDDCCKJCGJJJKJJJJFFBLJKIFMKMJJJLJJJFLKIJIJJJJK@ILLIILIIFGKIKI?GHGKGEB X0:i:1 X1:i:0 MD:Z:34G66 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.105205152 99 17 3562 60 93M8S = 3856 394 AATTCAAGTCAATGACAAATCAGAAAAAAAAACATATATATACGCAAACCAGTATCCTACTGTGTGTGTCGTTTGTTGTGTTTTCGACAGCTGTCCGTGTT ?D>?9HF>@ECDFDCDF;HBDCIID9797+7.7B>6=HL######### X0:i:1 X1:i:0 XC:i:93 MD:Z:25G67 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:AF@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.30258628 163 17 3583 60 101M = 3859 349 AGAAAAAAAAACATATATATACGCAAAACAGTATCCTACTGTGTGTGTCGTTTGTTGTGGTTTCTACAGCTGTCCGTGTGATAATAATTCCTCTAGTTCAA @@GCHH;6=>ECF=G4D==2BC*:=)6)'/-/4107;+4+@=E7,CBC:;C;BLB?HDGGB X0:i:1 X1:i:0 MD:Z:4G22C31T4G14T21 RG:Z:ERR229775 AM:i:25 NM:i:5 SM:i:25 MQ:i:60 XT:A:U BQ:Z:OOVRWWJELKO@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@IG +ERR229775.15284212 99 17 3585 60 88M13S = 3809 324 AAAAAAAAACATATATATACGCAAACCAGTATCCTACTGTGTGTGTCGTTTGTTGTGTTTTCGACAGCTGTCCGTGTTATAATAATTCCTCTAGTTCAAAT ?DEDDFFEIECHI;HHHAHI>HGLLGKIJGHFHCJIHEAGF:FJJDC8GIDFJBCFBHDGGH5GCFCBC=:AF/1826-7FJEIJHI############## X0:i:1 X1:i:0 XC:i:88 MD:Z:2G85 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:MRSRRTRPQ@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.15906182 163 17 3598 60 101M = 3862 364 TATATACGCAAACCAGTATCCTACTGTGTGTGTCGTTTGTTGTGTTTTCGACAGCTGTCCGTGTTATAATAATTCCTCTAGTTCAAATTTATTCATTTTTA BFEEEE@EKCDGA@>G@D?HJIIC;?=CD@JK?#;BJJ5DECBIABFDGHHCGFE?DJDGJGKDGI5BEIKHFFIKD-BHEFEGMGIIKGIJJIJGJGJDJFJ?FMMKHNKIKKNNNLDMKLNLKKKLMCKKKNKKJLKJKKMKLKKMJMJMKKKKJLLIIIJJHJJKIHHGHJIGFFB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.15603458 163 17 3626 60 101M = 3846 320 TGTGTCGTTTGTTGTGTTTTCGACAGCTGTCCGTGTTATAATAATTCCTCTAGTTCAAATTTATTCATTTTTAACTTCATAGTACCACATTCTACACACTG @EADDC9A@B@GH@GBCFB>>3CD?=;E@9>H;C;IJBIIIIIJIJHILHCBAF;=GI@BJDJE>>CFHKHIINE:BHIGH4E?EHJGG>AFMIFIEHAJ4 X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@B@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.80842527 99 17 3639 60 101M = 3844 305 GTGTTTTCGACAGCTGTCCGTGTTATAATAATTCCTCTAGTTCAAATTTATTCATTTTTAACTTCATAGTACCACATTCTACACACTGCCCATGTCCCCTC AGEFGHHG?JEIHJLJIKK@IJJJIJJMJJMJKMKMMMJMKKMKNNKKLJKLMKKLKLLKMKNLLKKKNLKKMKJJLLLLLJLILIPLJKILJIIGHFEJD X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.84503264 163 17 3670 60 101M = 3903 331 TTCCTCTAGTTCAAATTTATTCATTTTTAACTTCATAGTACCACATTCTACACACTGCCCATGTCCCCTCAAGCTTCCCCTGGCTCCTGCAACCACAAATC AEFCIEFFEB,CEHH?*;6936?956.-2%7)=C@3?BB.6C891FDGFJ?==>D@A:/DEB5@4BDG@D@ X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:EG@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B +ERR229775.78993145 147 17 3760 60 101M = 3530 -330 AACCACAAATCTACTCTCTGCCTCTGTGGGTTGACCTATTCTGGACACGTCATAGAAATAGAGTCCTGCAACACGTGGCCGTCTGTGTCTGGCTTCTCTCG 1@DGHHHFIJE@:CKDGIJIFHJBFBFGIHJJEFCHGEKEIIHGJGFAIKDJJMLJJIILDKIKIKIHHJEBBAIHJJE?HHIGGCGHHGABEHDEGEH9A X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.102280357 83 17 3772 60 101M = 3516 -356 ACTCTCTGCCTCTGTGGGTTGACCTATTCTGGACACGTCATAGAAATAGAGTCCTGCAACACGTGGCCGTCTGTGTCTGGCTTCTCTCGCTTAGCATCTTG ;EGFFHIFGIKIKGJIHGHJIDGIJHIJHIGGGHG>HLJJJNIJKKJMJNKLMKJLLJJJDCKKLKJAIGLJIJGIJJLKJLICJGJAIIIHKHHHIGHHB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229775 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.60297548 147 17 3785 60 101M = 3736 -149 GTGGGTTGACCTATTCTGGACACGTCATAGAAATAGAGTCCTGCAACACGTGGCCGTCTGTGTCTGGCTTCTCTCGCTTAGCATCTTGTTTCCAAGGTCCT @GFFFGJIJGIIHHKHJHHIHF@FIHIJLIHIFFJHJAGAIIHDGFDGAIEGHIAIKHIJIJKKIJKGKJD@IIAJKKEKJGDDJCGEE:,BJIGFGEFHFEBALJGJ?K4E;KILICFJELIFKJB>AHAF@HFGEGGGC? X0:i:1 X1:i:0 MD:Z:90A10 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.105205152 147 17 3856 60 101M = 3562 -394 TCTCGCTTAGCATCTTGTTTCCAAGGTCCTCCCACAGTGTAGCATGCACCTGCTACACTCCTTCTTAGGGCTGATATTCCGCGCACCTGCTACACTCCTTC #BE=GGHILIIHKHHJGJHJDHEKD;+EBF?C>FFJ?E?DCIFEIGB>=HGBDILKGIFB>FI=9*=<><'?;C69?8,6?DD253-72,D9>: X0:i:1 X1:i:0 MD:Z:80A20 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.30258628 83 17 3859 60 27S74M = 3583 -349 TCGTGGCCGTCTGTGTCTGGCTTCTCTCGCTTAGCATCTTGTTTCCAAGGTCCTCCCACAGTGTAGCATGCACCTGCTACACTCCTTCTTAGGGCTGATAT ############################FLLJHF-.LGLKHKKHCIBLHBHDB?@@;7IH=9>7/5HIE+A@EHICFFIGIJ@AGI?>KHAGEFGHE:DE7 X0:i:1 X1:i:0 XC:i:74 MD:Z:74 RG:Z:ERR229775 AM:i:25 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.15906182 83 17 3862 60 101M = 3598 -364 TTAGCATCTTGTTTCCAAGGTCCTCCCACAGTGTAGCATGCACCTGCTACACTCCTTCTTAGGGCTGATATTCCGCGCACCTGCTACACTCCTTCTTATGG FEFFGGJHCKHHKKGHILFE@:EBCFIIHLEHHIMHEEIFBEGJJJKIIBAIGJMMLMMJMIIJIJKJJJMGLAKAKFFEJIDGHIHCJK@GJJHJGGHEB X0:i:1 X1:i:0 MD:Z:74A26 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:D@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229775.104583040 99 17 3884 37 84M17S = 4097 298 CTCCCACAGTGTAGCATGCACCTGCTACACTCCTTCTTAGGGCTGATATTCCGCGCACCTGCTACACTCCTTCTTATGGCTGATATTCCACGCACCTGCTA ?HFEEHFHBC7EGAHIHCHFDHL?HJ=FI48C>KFJL=EKCCJJJALKHJLJLLIIHJFKHIIGGKJHCG?EFBHIGDCF>F@CCDFEGEGFF@ X0:i:1 X1:i:0 MD:Z:39A61 RG:Z:ERR229775 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B +ERR229775.84503264 83 17 3903 60 2S99M = 3670 -331 GCCCCTGCTACCCTCCTTCTTAGGGCTGATATTCCGCGCCCCTGCTACCCTCCTTCTTATGGCTGATATTCCACGCACCTGCTACACTCCTTCTTAGGGCT ###?DDA5-;91@B:HBJ<:89-=F65868-%4C9E5-=>9C+9C9H;AFC7GEBCCJJILKJHHAIHELLIJJD=C>IFEIIJIJHLEEGEB X0:i:1 X1:i:0 XC:i:99 MD:Z:0A8A23A3A8A52 RG:Z:ERR229775 AM:i:25 NM:i:5 SM:i:25 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ diff --git a/test/mpileup/mpileup.4.bam b/test/mpileup/mpileup.4.bam new file mode 100644 index 0000000000000000000000000000000000000000..bbcb8b19c9ddc14ef5469833f6b0a144b9ffa6e9 GIT binary patch literal 26690 zcmV)HK)t^oiwFb&00000{{{d;LjnNT02PnHO2jY}MKid1UHK*QlGbM4TeY1^8%ScN zLANFCOmRSGMDz#!GUI`}I&k51t=s(yA)2v=SI_bRAwKhZyM3K5*YtfZns|hmg$C=n zQi$LlIZ?uTO-QShQt#~PwvzS=w;I~W{?M6HLkv9re57m9OaqvnpQcGE(z*uQ z@i-t#RI{0vb^biRUzS;-B#166`UisHiZmQNyI|Y^!LqUT#Tnm1A307TUnr`IU9Pyx zlUlsp3-JeTJKGM~0000ViwFb&00000{{{d;LjnL#PSw48jAVO$7uGX(UOmq~r%!jC 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C <*> 0 . DP=18;DPR=17,0;I16=17,0,0,0,688,29762,0,0,958,55682,0,0,332,7446,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,27,189:9:0:0:9,0,0,0:9,0 0,9,108:3:0:0:3,0,0,0:3,0 0,15,134:5:0:0:5,0,0,0:5,0 +17 101 . C <*> 0 . DP=18;DPR=17,0;I16=17,0,0,0,650,27530,0,0,958,55682,0,0,331,7303,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,27,182:9:0:0:9,0,0,0:9,0 0,9,99:3:0:0:3,0,0,0:3,0 0,15,132:5:0:0:5,0,0,0:5,0 +17 102 . C <*> 0 . DP=18;DPR=17,0;I16=17,0,0,0,695,30453,0,0,958,55682,0,0,330,7178,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,27,188:9:0:0:9,0,0,0:9,0 0,9,111:3:0:0:3,0,0,0:3,0 0,15,139:5:0:0:5,0,0,0:5,0 +17 103 . T <*> 0 . DP=18;DPR=16,0;I16=16,0,0,0,692,31998,0,0,929,54841,0,0,323,7035,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,24,189:8:0:0:8,0,0,0:8,0 0,9,108:3:0:0:3,0,0,0:3,0 0,15,147:5:0:0:5,0,0,0:5,0 +17 104 . G <*> 0 . DP=18;DPR=15,0;I16=15,0,0,0,611,26723,0,0,900,54000,0,0,295,6259,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,24,178:8:0:0:8,0,0,0:8,0 0,6,89:2:0:0:2,0,0,0:2,0 0,15,133:5:0:0:5,0,0,0:5,0 +17 105 . G <*> 0 . DP=19;DPR=17,0;I16=17,0,0,0,604,23936,0,0,989,58441,0,0,317,6751,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,27,170:9:0:0:9,0,0,0:9,0 0,9,97:3:0:0:3,0,0,0:3,0 0,15,125:5:0:0:5,0,0,0:5,0 +17 106 . G <*> 0 . DP=19;DPR=17,0;I16=17,0,0,0,644,26574,0,0,989,58441,0,0,299,6093,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,190:10:0:0:10,0,0,0:10,0 0,6,85:2:0:0:2,0,0,0:2,0 0,15,124:5:0:0:5,0,0,0:5,0 +17 107 . C <*> 0 . DP=19;DPR=17,0;I16=17,0,0,0,694,30064,0,0,989,58441,0,0,313,6543,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,27,192:9:0:0:9,0,0,0:9,0 0,9,108:3:0:0:3,0,0,0:3,0 0,15,136:5:0:0:5,0,0,0:5,0 +17 108 . C <*> 0 . DP=19;DPR=17,0;I16=17,0,0,0,692,30148,0,0,989,58441,0,0,310,6420,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,27,190:9:0:0:9,0,0,0:9,0 0,9,108:3:0:0:3,0,0,0:3,0 0,15,135:5:0:0:5,0,0,0:5,0 +17 109 . T <*> 0 . DP=19;DPR=17,0;I16=17,0,0,0,741,34273,0,0,989,58441,0,0,307,6319,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,27,195:9:0:0:9,0,0,0:9,0 0,9,110:3:0:0:3,0,0,0:3,0 0,15,150:5:0:0:5,0,0,0:5,0 +17 110 . G <*> 0 . DP=19;DPR=17,0;I16=17,0,0,0,704,31276,0,0,989,58441,0,0,304,6240,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,27,194:9:0:0:9,0,0,0:9,0 0,9,104:3:0:0:3,0,0,0:3,0 0,15,136:5:0:0:5,0,0,0:5,0 +17 111 . G <*> 0 . DP=19;DPR=16,0;I16=16,0,0,0,584,24362,0,0,929,54841,0,0,272,5416,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,167:10:0:0:10,0,0,0:10,0 0,6,88:2:0:0:2,0,0,0:2,0 0,12,118:4:0:0:4,0,0,0:4,0 +17 112 . C <*> 0 . DP=19;DPR=17,0;I16=17,0,0,0,680,29854,0,0,989,58441,0,0,296,6052,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,27,191:9:0:0:9,0,0,0:9,0 0,9,95:3:0:0:3,0,0,0:3,0 0,15,135:5:0:0:5,0,0,0:5,0 +17 113 . A <*> 0 . DP=19;DPR=16,0;I16=16,0,0,0,645,28035,0,0,960,57600,0,0,266,5318,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,27,176:9:0:0:9,0,0,0:9,0 0,6,87:2:0:0:2,0,0,0:2,0 0,15,139:5:0:0:5,0,0,0:5,0 +17 114 . C <*> 0 . DP=19;DPR=17,0;I16=17,0,0,0,674,28788,0,0,989,58441,0,0,286,5856,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,27,182:9:0:0:9,0,0,0:9,0 0,9,103:3:0:0:3,0,0,0:3,0 0,15,133:5:0:0:5,0,0,0:5,0 +17 115 . C <*> 0 . DP=21;DPR=18,0;I16=18,0,0,0,708,30546,0,0,1049,62041,0,0,274,5490,0,0;QS=3,0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,189:10:0:0:10,0,0,0:10,0 0,6,89:2:0:0:2,0,0,0:2,0 0,18,147:6:0:0:6,0,0,0:6,0 +17 116 . A <*> 0 . DP=21;DPR=18,0;I16=17,1,0,0,727,31755,0,0,1049,62041,0,0,253,5079,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,27,183:9:0:0:9,0,0,0:9,0 0,6,90:2:0:0:2,0,0,0:2,0 0,21,175:7:0:0:6,1,0,0:7,0 +17 117 . G <*> 0 . DP=21;DPR=18,0;I16=17,1,0,0,712,30478,0,0,1049,62041,0,0,249,5019,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,27,183:9:0:0:9,0,0,0:9,0 0,6,85:2:0:0:2,0,0,0:2,0 0,21,177:7:0:0:6,1,0,0:7,0 +17 118 . G <*> 0 . DP=20;DPR=17,0;I16=16,1,0,0,636,26574,0,0,958,55682,0,0,266,5426,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,27,175:9:0:0:9,0,0,0:9,0 0,3,60:1:0:0:1,0,0,0:1,0 0,21,162:7:0:0:6,1,0,0:7,0 +17 119 . G <*> 0 . DP=19;DPR=17,0;I16=16,1,0,0,629,26439,0,0,958,55682,0,0,267,5553,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,24,175:8:0:0:8,0,0,0:8,0 0,6,73:2:0:0:2,0,0,0:2,0 0,21,160:7:0:0:6,1,0,0:7,0 +17 120 . A <*> 0 . DP=19;DPR=17,0;I16=16,1,0,0,672,29188,0,0,958,55682,0,0,264,5518,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,24,175:8:0:0:8,0,0,0:8,0 0,6,83:2:0:0:2,0,0,0:2,0 0,21,171:7:0:0:6,1,0,0:7,0 +17 121 . G <*> 0 . DP=19;DPR=17,0;I16=16,1,0,0,662,28460,0,0,958,55682,0,0,260,5454,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,24,181:8:0:0:8,0,0,0:8,0 0,6,80:2:0:0:2,0,0,0:2,0 0,21,168:7:0:0:6,1,0,0:7,0 +17 122 . C <*> 0 . DP=20;DPR=18,0;I16=17,1,0,0,716,31224,0,0,1018,59282,0,0,256,5410,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,24,181:8:0:0:8,0,0,0:8,0 0,9,99:3:0:0:3,0,0,0:3,0 0,21,178:7:0:0:6,1,0,0:7,0 +17 123 . T <*> 0 . DP=18;DPR=16,0;I16=15,1,0,0,661,29997,0,0,898,52082,0,0,255,5385,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,167:7:0:0:7,0,0,0:7,0 0,9,112:3:0:0:3,0,0,0:3,0 0,18,166:6:0:0:5,1,0,0:6,0 +17 124 . T <*> 0 . DP=19;DPR=18,0;I16=17,1,0,0,626,24802,0,0,987,56523,0,0,279,6003,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,27,154:9:0:0:9,0,0,0:9,0 0,9,104:3:0:0:3,0,0,0:3,0 0,18,154:6:0:0:5,1,0,0:6,0 +17 125 . A <*> 0 . DP=18;DPR=16,0;I16=15,1,0,0,611,25689,0,0,898,52082,0,0,254,5340,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,154:7:0:0:7,0,0,0:7,0 0,9,104:3:0:0:3,0,0,0:3,0 0,18,162:6:0:0:5,1,0,0:6,0 +17 126 . A <*> 0 . DP=18;DPR=17,0;I16=16,1,0,0,648,27366,0,0,927,52923,0,0,279,5947,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,24,162:8:0:0:8,0,0,0:8,0 0,9,107:3:0:0:3,0,0,0:3,0 0,18,174:6:0:0:5,1,0,0:6,0 +17 127 . C <*> 0 . DP=18;DPR=17,0;I16=16,1,0,0,646,26972,0,0,927,52923,0,0,279,5949,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,24,163:8:0:0:8,0,0,0:8,0 0,9,109:3:0:0:3,0,0,0:3,0 0,18,160:6:0:0:5,1,0,0:6,0 +17 128 . A <*> 0 . DP=18;DPR=17,0;I16=16,1,0,0,673,28797,0,0,927,52923,0,0,279,5971,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,24,169:8:0:0:8,0,0,0:8,0 0,9,111:3:0:0:3,0,0,0:3,0 0,18,162:6:0:0:5,1,0,0:6,0 +17 129 . A <*> 0 . DP=17;DPR=16,0;I16=15,1,0,0,645,27891,0,0,867,49323,0,0,280,6012,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,24,168:8:0:0:8,0,0,0:8,0 0,9,113:3:0:0:3,0,0,0:3,0 0,15,159:5:0:0:4,1,0,0:5,0 +17 130 . A <*> 0 . DP=17;DPR=16,0;I16=15,1,0,0,641,27295,0,0,867,49323,0,0,281,6071,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,24,169:8:0:0:8,0,0,0:8,0 0,9,113:3:0:0:3,0,0,0:3,0 0,15,152:5:0:0:4,1,0,0:5,0 +17 131 . C <*> 0 . DP=16;DPR=15,0;I16=14,1,0,0,606,25732,0,0,838,48482,0,0,256,5472,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,167:7:0:0:7,0,0,0:7,0 0,9,110:3:0:0:3,0,0,0:3,0 0,15,147:5:0:0:4,1,0,0:5,0 +17 132 . A <*> 0 . DP=16;DPR=15,0;I16=14,1,0,0,627,27579,0,0,838,48482,0,0,256,5514,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,169:7:0:0:7,0,0,0:7,0 0,9,110:3:0:0:3,0,0,0:3,0 0,15,151:5:0:0:4,1,0,0:5,0 +17 133 . T <*> 0 . DP=15;DPR=15,0;I16=13,2,0,0,584,22816,0,0,838,48482,0,0,282,6196,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,163:7:0:0:7,0,0,0:7,0 0,9,105:3:0:0:2,1,0,0:3,0 0,15,150:5:0:0:4,1,0,0:5,0 +17 134 . C <*> 0 . DP=15;DPR=15,0;I16=13,2,0,0,607,24653,0,0,838,48482,0,0,283,6267,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,177:7:0:0:7,0,0,0:7,0 0,9,105:3:0:0:2,1,0,0:3,0 0,15,152:5:0:0:4,1,0,0:5,0 +17 135 . T <*> 0 . DP=15;DPR=15,0;I16=13,2,0,0,600,24178,0,0,838,48482,0,0,284,6352,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,173:7:0:0:7,0,0,0:7,0 0,9,106:3:0:0:2,1,0,0:3,0 0,15,156:5:0:0:4,1,0,0:5,0 +17 136 . G <*> 0 . DP=15;DPR=15,0;I16=13,2,0,0,574,22258,0,0,838,48482,0,0,286,6450,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,172:7:0:0:7,0,0,0:7,0 0,9,105:3:0:0:2,1,0,0:3,0 0,15,134:5:0:0:4,1,0,0:5,0 +17 137 . T <*> 0 . DP=15;DPR=15,0;I16=13,2,0,0,563,21377,0,0,838,48482,0,0,289,6561,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,160:7:0:0:7,0,0,0:7,0 0,9,104:3:0:0:2,1,0,0:3,0 0,15,139:5:0:0:4,1,0,0:5,0 +17 138 . C <*> 0 . DP=15;DPR=15,0;I16=13,2,0,0,584,23088,0,0,838,48482,0,0,291,6637,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,172:7:0:0:7,0,0,0:7,0 0,9,108:3:0:0:2,1,0,0:3,0 0,15,142:5:0:0:4,1,0,0:5,0 +17 139 . C <*> 0 . DP=15;DPR=15,0;I16=13,2,0,0,554,20790,0,0,838,48482,0,0,292,6680,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,161:7:0:0:7,0,0,0:7,0 0,9,106:3:0:0:2,1,0,0:3,0 0,15,143:5:0:0:4,1,0,0:5,0 +17 140 . A <*> 0 . DP=15;DPR=15,0;I16=13,2,0,0,583,22789,0,0,838,48482,0,0,292,6690,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,163:7:0:0:7,0,0,0:7,0 0,9,107:3:0:0:2,1,0,0:3,0 0,15,153:5:0:0:4,1,0,0:5,0 +17 141 . G <*> 0 . DP=14;DPR=14,0;I16=12,2,0,0,534,20750,0,0,778,44882,0,0,292,6664,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,158:6:0:0:6,0,0,0:6,0 0,9,108:3:0:0:2,1,0,0:3,0 0,15,142:5:0:0:4,1,0,0:5,0 +17 142 . C <*> 0 . DP=14;DPR=14,0;I16=12,2,0,0,503,18593,0,0,778,44882,0,0,292,6650,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,157:6:0:0:6,0,0,0:6,0 0,9,97:3:0:0:2,1,0,0:3,0 0,15,129:5:0:0:4,1,0,0:5,0 +17 143 . G <*> 0 . DP=14;DPR=13,0;I16=11,2,0,0,415,13657,0,0,718,41282,0,0,285,6599,0,0;QS=3,0;MQSB=0.590909;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,128:6:0:0:6,0,0,0:6,0 0,9,95:3:0:0:2,1,0,0:3,0 0,12,97:4:0:0:3,1,0,0:4,0 +17 144 . A <*> 0 . DP=14;DPR=14,0;I16=12,2,0,0,519,19725,0,0,778,44882,0,0,291,6609,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,152:6:0:0:6,0,0,0:6,0 0,9,105:3:0:0:2,1,0,0:3,0 0,15,129:5:0:0:4,1,0,0:5,0 +17 145 . A <*> 0 . DP=14;DPR=14,0;I16=12,2,0,0,527,20289,0,0,778,44882,0,0,290,6584,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,153:6:0:0:6,0,0,0:6,0 0,9,106:3:0:0:2,1,0,0:3,0 0,15,138:5:0:0:4,1,0,0:5,0 +17 146 . T <*> 0 . DP=14;DPR=14,0;I16=12,2,0,0,514,19484,0,0,778,44882,0,0,289,6573,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,152:6:0:0:6,0,0,0:6,0 0,9,103:3:0:0:2,1,0,0:3,0 0,15,128:5:0:0:4,1,0,0:5,0 +17 147 . A <*> 0 . DP=14;DPR=14,0;I16=12,2,0,0,515,19213,0,0,778,44882,0,0,288,6576,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,150:6:0:0:6,0,0,0:6,0 0,9,99:3:0:0:2,1,0,0:3,0 0,15,140:5:0:0:4,1,0,0:5,0 +17 148 . C <*> 0 . DP=14;DPR=14,0;I16=12,2,0,0,541,21019,0,0,778,44882,0,0,286,6542,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,157:6:0:0:6,0,0,0:6,0 0,9,106:3:0:0:2,1,0,0:3,0 0,15,146:5:0:0:4,1,0,0:5,0 +17 149 . C <*> 0 . DP=14;DPR=14,0;I16=12,2,0,0,512,19326,0,0,778,44882,0,0,283,6471,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,148:6:0:0:6,0,0,0:6,0 0,9,109:3:0:0:2,1,0,0:3,0 0,15,140:5:0:0:4,1,0,0:5,0 +17 150 . T <*> 0 . DP=13;DPR=13,0;I16=11,2,0,0,511,20251,0,0,749,44041,0,0,280,6362,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,153:6:0:0:6,0,0,0:6,0 0,6,84:2:0:0:1,1,0,0:2,0 0,15,152:5:0:0:4,1,0,0:5,0 +17 151 . G <*> 0 . DP=13;DPR=13,0;I16=11,2,0,0,506,19826,0,0,749,44041,0,0,277,6263,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,157:6:0:0:6,0,0,0:6,0 0,6,84:2:0:0:1,1,0,0:2,0 0,15,144:5:0:0:4,1,0,0:5,0 +17 152 . C <*> 0 . DP=14;DPR=14,0;I16=12,2,0,0,543,21283,0,0,809,47641,0,0,274,6174,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,168:7:0:0:7,0,0,0:7,0 0,6,84:2:0:0:1,1,0,0:2,0 0,15,146:5:0:0:4,1,0,0:5,0 +17 153 . A <*> 0 . DP=14;DPR=14,0;I16=12,2,0,0,536,20594,0,0,809,47641,0,0,272,6096,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,156:7:0:0:7,0,0,0:7,0 0,6,81:2:0:0:1,1,0,0:2,0 0,15,153:5:0:0:4,1,0,0:5,0 +17 154 . T <*> 0 . DP=14;DPR=14,0;I16=12,2,0,0,523,20051,0,0,809,47641,0,0,270,6030,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,159:7:0:0:7,0,0,0:7,0 0,6,83:2:0:0:1,1,0,0:2,0 0,15,139:5:0:0:4,1,0,0:5,0 +17 155 . C <*> 0 . DP=14;DPR=14,0;I16=12,2,0,0,542,21254,0,0,809,47641,0,0,268,5976,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,172:7:0:0:7,0,0,0:7,0 0,6,85:2:0:0:1,1,0,0:2,0 0,15,139:5:0:0:4,1,0,0:5,0 +17 156 . C <*> 0 . DP=14;DPR=14,0;I16=12,2,0,0,536,20884,0,0,809,47641,0,0,266,5934,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,163:7:0:0:7,0,0,0:7,0 0,6,84:2:0:0:1,1,0,0:2,0 0,15,150:5:0:0:4,1,0,0:5,0 +17 157 . C <*> 0 . DP=14;DPR=14,0;I16=12,2,0,0,555,22081,0,0,809,47641,0,0,264,5904,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,169:7:0:0:7,0,0,0:7,0 0,6,85:2:0:0:1,1,0,0:2,0 0,15,149:5:0:0:4,1,0,0:5,0 +17 158 . T <*> 0 . DP=14;DPR=14,0;I16=12,2,0,0,568,23154,0,0,809,47641,0,0,262,5886,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,170:7:0:0:7,0,0,0:7,0 0,6,84:2:0:0:1,1,0,0:2,0 0,15,159:5:0:0:4,1,0,0:5,0 +17 159 . A <*> 0 . DP=15;DPR=14,0;I16=12,2,0,0,519,19467,0,0,809,47641,0,0,260,5880,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,157:7:0:0:7,0,0,0:7,0 0,6,83:2:0:0:1,1,0,0:2,0 0,15,135:5:0:0:4,1,0,0:5,0 +17 160 . G <*> 0 . DP=15;DPR=15,0;I16=13,2,0,0,547,20633,0,0,869,51241,0,0,259,5887,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,165:7:0:0:7,0,0,0:7,0 0,6,85:2:0:0:1,1,0,0:2,0 0,18,139:6:0:0:5,1,0,0:6,0 +17 161 . A <*> 0 . DP=15;DPR=15,0;I16=13,2,0,0,568,21610,0,0,869,51241,0,0,258,5908,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,157:7:0:0:7,0,0,0:7,0 0,6,83:2:0:0:1,1,0,0:2,0 0,18,162:6:0:0:5,1,0,0:6,0 +17 162 . A <*> 0 . DP=15;DPR=15,0;I16=13,2,0,0,557,21139,0,0,869,51241,0,0,255,5843,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,147:7:0:0:7,0,0,0:7,0 0,6,87:2:0:0:1,1,0,0:2,0 0,18,167:6:0:0:5,1,0,0:6,0 +17 163 . G <*> 0 . DP=14;DPR=14,0;I16=12,2,0,0,503,18645,0,0,809,47641,0,0,253,5791,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,153:7:0:0:7,0,0,0:7,0 0,6,79:2:0:0:1,1,0,0:2,0 0,15,138:5:0:0:4,1,0,0:5,0 +17 164 . T <*> 0 . DP=14;DPR=14,0;I16=12,2,0,0,460,15968,0,0,809,47641,0,0,252,5750,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,131:6:0:0:6,0,0,0:6,0 0,6,79:2:0:0:1,1,0,0:2,0 0,18,136:6:0:0:5,1,0,0:6,0 +17 165 . G <*> 0 . DP=14;DPR=12,0;I16=10,2,0,0,456,17460,0,0,689,40441,0,0,226,5094,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,149:6:0:0:6,0,0,0:6,0 0,6,80:2:0:0:1,1,0,0:2,0 0,12,122:4:0:0:3,1,0,0:4,0 +17 166 . A <*> 0 . DP=14;DPR=13,0;I16=11,2,0,0,496,19138,0,0,749,44041,0,0,227,5077,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,145:6:0:0:6,0,0,0:6,0 0,6,82:2:0:0:1,1,0,0:2,0 0,15,148:5:0:0:4,1,0,0:5,0 +17 167 . A <*> 0 . DP=14;DPR=13,0;I16=11,2,0,0,477,17851,0,0,749,44041,0,0,227,5071,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,132:6:0:0:6,0,0,0:6,0 0,6,86:2:0:0:1,1,0,0:2,0 0,15,147:5:0:0:4,1,0,0:5,0 +17 168 . G <*> 0 . DP=14;DPR=14,0;I16=12,2,0,0,481,18015,0,0,809,47641,0,0,252,5702,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,145:6:0:0:6,0,0,0:6,0 0,6,82:2:0:0:1,1,0,0:2,0 0,18,140:6:0:0:5,1,0,0:6,0 +17 169 . C <*> 0 . DP=13;DPR=12,0;I16=10,2,0,0,402,14224,0,0,689,40441,0,0,227,5045,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,15,106:5:0:0:5,0,0,0:5,0 0,6,76:2:0:0:1,1,0,0:2,0 0,15,145:5:0:0:4,1,0,0:5,0 +17 170 . C <*> 0 . DP=13;DPR=13,0;I16=11,2,0,0,447,16383,0,0,749,44041,0,0,251,5601,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,15,128:5:0:0:5,0,0,0:5,0 0,6,80:2:0:0:1,1,0,0:2,0 0,18,143:6:0:0:5,1,0,0:6,0 +17 171 . A <*> 0 . DP=13;DPR=13,0;I16=11,2,0,0,500,19366,0,0,749,44041,0,0,250,5546,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,15,134:5:0:0:5,0,0,0:5,0 0,6,81:2:0:0:1,1,0,0:2,0 0,18,166:6:0:0:5,1,0,0:6,0 +17 172 . C <*> 0 . DP=13;DPR=12,0;I16=10,2,0,0,439,16395,0,0,689,40441,0,0,241,5441,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,15,138:5:0:0:5,0,0,0:5,0 0,6,75:2:0:0:1,1,0,0:2,0 0,15,129:5:0:0:4,1,0,0:5,0 +17 173 . C <*> 0 . DP=13;DPR=13,0;I16=11,2,0,0,435,15225,0,0,749,44041,0,0,248,5478,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,15,121:5:0:0:5,0,0,0:5,0 0,6,76:2:0:0:1,1,0,0:2,0 0,18,146:6:0:0:5,1,0,0:6,0 +17 174 . G <*> 0 . DP=13;DPR=12,0;I16=11,1,0,0,351,10685,0,0,689,40441,0,0,238,5364,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,15,111:5:0:0:5,0,0,0:5,0 0,3,27:1:0:0:1,0,0,0:1,0 0,18,117:6:0:0:5,1,0,0:6,0 +17 175 . C <*> 0 . DP=14;DPR=14,0;I16=13,1,0,0,511,19161,0,0,809,47641,0,0,249,5463,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,143:6:0:0:6,0,0,0:6,0 0,3,41:1:0:0:1,0,0,0:1,0 0,21,175:7:0:0:6,1,0,0:7,0 +17 176 . C <*> 0 . DP=14;DPR=14,0;I16=13,1,0,0,489,17733,0,0,809,47641,0,0,251,5477,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,146:6:0:0:6,0,0,0:6,0 0,3,44:1:0:0:1,0,0,0:1,0 0,21,152:7:0:0:6,1,0,0:7,0 +17 177 . C <*> 0 . DP=14;DPR=14,0;I16=13,1,0,0,488,17328,0,0,809,47641,0,0,253,5507,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,138:6:0:0:6,0,0,0:6,0 0,3,44:1:0:0:1,0,0,0:1,0 0,21,158:7:0:0:6,1,0,0:7,0 +17 178 . A <*> 0 . DP=14;DPR=14,0;I16=13,1,0,0,519,19485,0,0,809,47641,0,0,254,5502,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,147:6:0:0:6,0,0,0:6,0 0,3,42:1:0:0:1,0,0,0:1,0 0,21,172:7:0:0:6,1,0,0:7,0 +17 179 . A <*> 0 . DP=14;DPR=14,0;I16=13,1,0,0,478,17278,0,0,809,47641,0,0,255,5511,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,134:6:0:0:6,0,0,0:6,0 0,3,44:1:0:0:1,0,0,0:1,0 0,21,170:7:0:0:6,1,0,0:7,0 +17 180 . A <*> 0 . DP=14;DPR=13,0;I16=12,1,0,0,425,14653,0,0,749,44041,0,0,250,5498,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,126:6:0:0:6,0,0,0:6,0 0,3,43:1:0:0:1,0,0,0:1,0 0,18,148:6:0:0:5,1,0,0:6,0 +17 181 . G <*> 0 . DP=14;DPR=12,0;I16=11,1,0,0,450,17152,0,0,689,40441,0,0,233,5233,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,156:6:0:0:6,0,0,0:6,0 0,3,41:1:0:0:1,0,0,0:1,0 0,15,138:5:0:0:4,1,0,0:5,0 +17 182 . A <*> 0 . DP=15;DPR=15,0;I16=14,1,0,0,515,18235,0,0,869,51241,0,0,258,5622,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,150:7:0:0:7,0,0,0:7,0 0,3,43:1:0:0:1,0,0,0:1,0 0,21,159:7:0:0:6,1,0,0:7,0 +17 183 . C <*> 0 . DP=15;DPR=14,0;I16=13,1,0,0,483,17419,0,0,809,47641,0,0,235,5063,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,159:7:0:0:7,0,0,0:7,0 0,3,40:1:0:0:1,0,0,0:1,0 0,18,139:6:0:0:5,1,0,0:6,0 +17 184 . A <*> 0 . DP=15;DPR=15,0;I16=14,1,0,0,535,19667,0,0,869,51241,0,0,262,5770,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,158:7:0:0:7,0,0,0:7,0 0,3,41:1:0:0:1,0,0,0:1,0 0,21,163:7:0:0:6,1,0,0:7,0 +17 185 . C <*> 0 . DP=15;DPR=14,0;I16=13,1,0,0,487,17295,0,0,809,47641,0,0,238,5192,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,150:7:0:0:7,0,0,0:7,0 0,3,38:1:0:0:1,0,0,0:1,0 0,18,160:6:0:0:5,1,0,0:6,0 +17 186 . G <*> 0 . DP=15;DPR=13,0;I16=12,1,0,0,381,11429,0,0,749,44041,0,0,239,5253,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,117:6:0:0:6,0,0,0:6,0 0,3,32:1:0:0:1,0,0,0:1,0 0,18,124:6:0:0:5,1,0,0:6,0 +17 187 . C <*> 0 . DP=14;DPR=14,0;I16=13,1,0,0,511,18979,0,0,809,47641,0,0,266,5952,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,147:6:0:0:6,0,0,0:6,0 0,3,38:1:0:0:1,0,0,0:1,0 0,21,172:7:0:0:6,1,0,0:7,0 +17 188 . C <*> 0 . DP=14;DPR=14,0;I16=13,1,0,0,496,18042,0,0,809,47641,0,0,267,5989,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,147:6:0:0:6,0,0,0:6,0 0,3,37:1:0:0:1,0,0,0:1,0 0,21,162:7:0:0:6,1,0,0:7,0 +17 189 . C <*> 0 . DP=15;DPR=15,0;I16=13,2,0,0,552,20504,0,0,838,48482,0,0,268,6040,0,0;QS=3,0;MQSB=0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,152:6:0:0:6,0,0,0:6,0 0,6,67:2:0:0:1,1,0,0:2,0 0,21,167:7:0:0:6,1,0,0:7,0 +17 190 . A <*> 0 . DP=15;DPR=14,0;I16=12,2,0,0,500,18230,0,0,778,44882,0,0,243,5381,0,0;QS=3,0;MQSB=0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,138:6:0:0:6,0,0,0:6,0 0,6,68:2:0:0:1,1,0,0:2,0 0,18,159:6:0:0:5,1,0,0:6,0 +17 191 . T <*> 0 . DP=15;DPR=15,0;I16=13,2,0,0,534,19276,0,0,838,48482,0,0,267,5939,0,0;QS=3,0;MQSB=0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,143:6:0:0:6,0,0,0:6,0 0,6,67:2:0:0:1,1,0,0:2,0 0,21,169:7:0:0:6,1,0,0:7,0 +17 192 . G <*> 0 . DP=15;DPR=15,0;I16=13,2,0,0,499,17439,0,0,838,48482,0,0,266,5890,0,0;QS=3,0;MQSB=0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,143:6:0:0:6,0,0,0:6,0 0,6,67:2:0:0:1,1,0,0:2,0 0,21,151:7:0:0:6,1,0,0:7,0 +17 193 . T <*> 0 . DP=15;DPR=15,0;I16=13,2,0,0,505,17811,0,0,838,48482,0,0,265,5859,0,0;QS=3,0;MQSB=0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,140:6:0:0:6,0,0,0:6,0 0,6,63:2:0:0:1,1,0,0:2,0 0,21,157:7:0:0:6,1,0,0:7,0 +17 194 . C <*> 0 . DP=14;DPR=14,0;I16=12,2,0,0,467,16569,0,0,778,44882,0,0,265,5845,0,0;QS=3,0;MQSB=0;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,142:6:0:0:6,0,0,0:6,0 0,6,67:2:0:0:1,1,0,0:2,0 0,18,145:6:0:0:5,1,0,0:6,0 +17 195 . C <*> 0 . DP=14;DPR=14,0;I16=11,3,0,0,503,18647,0,0,747,42123,0,0,266,5846,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,159:6:0:0:5,1,0,0:6,0 0,6,71:2:0:0:1,1,0,0:2,0 0,18,160:6:0:0:5,1,0,0:6,0 +17 196 . A <*> 0 . DP=14;DPR=14,0;I16=11,3,0,0,482,17400,0,0,747,42123,0,0,268,5862,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,166:6:0:0:5,1,0,0:6,0 0,6,69:2:0:0:1,1,0,0:2,0 0,18,138:6:0:0:5,1,0,0:6,0 +17 197 . G <*> 0 . DP=14;DPR=14,0;I16=11,3,0,0,481,17391,0,0,747,42123,0,0,270,5894,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,164:6:0:0:5,1,0,0:6,0 0,6,68:2:0:0:1,1,0,0:2,0 0,18,134:6:0:0:5,1,0,0:6,0 +17 198 . C <*> 0 . DP=14;DPR=14,0;I16=11,3,0,0,539,20957,0,0,747,42123,0,0,271,5893,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,172:6:0:0:5,1,0,0:6,0 0,6,70:2:0:0:1,1,0,0:2,0 0,18,164:6:0:0:5,1,0,0:6,0 +17 199 . T <*> 0 . DP=14;DPR=14,0;I16=11,3,0,0,505,19197,0,0,747,42123,0,0,271,5861,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,162:6:0:0:5,1,0,0:6,0 0,6,73:2:0:0:1,1,0,0:2,0 0,18,154:6:0:0:5,1,0,0:6,0 +17 200 . T <*> 0 . DP=15;DPR=15,0;I16=11,4,0,0,544,19918,0,0,776,42964,0,0,270,5798,0,0;QS=3,0;MQSB=0.0161635;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,161:6:0:0:5,1,0,0:6,0 0,9,89:3:0:0:1,2,0,0:3,0 0,18,154:6:0:0:5,1,0,0:6,0 +17 201 . A <*> 0 . DP=16;DPR=16,0;I16=12,4,0,0,568,20416,0,0,836,46564,0,0,269,5703,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,171:7:0:0:6,1,0,0:7,0 0,9,89:3:0:0:1,2,0,0:3,0 0,18,157:6:0:0:5,1,0,0:6,0 +17 202 . A <*> 0 . DP=16;DPR=16,0;I16=12,4,0,0,566,20590,0,0,836,46564,0,0,269,5627,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,178:7:0:0:6,1,0,0:7,0 0,9,84:3:0:0:1,2,0,0:3,0 0,18,163:6:0:0:5,1,0,0:6,0 +17 203 . C <*> 0 . DP=16;DPR=16,0;I16=12,4,0,0,557,20119,0,0,836,46564,0,0,269,5571,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,166:7:0:0:6,1,0,0:7,0 0,9,90:3:0:0:1,2,0,0:3,0 0,18,153:6:0:0:5,1,0,0:6,0 +17 204 . C <*> 0 . DP=16;DPR=16,0;I16=12,4,0,0,591,22379,0,0,836,46564,0,0,269,5535,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,173:7:0:0:6,1,0,0:7,0 0,9,91:3:0:0:1,2,0,0:3,0 0,18,163:6:0:0:5,1,0,0:6,0 +17 205 . T <*> 0 . DP=16;DPR=16,0;I16=12,4,0,0,635,25281,0,0,836,46564,0,0,269,5519,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,188:7:0:0:6,1,0,0:7,0 0,9,95:3:0:0:1,2,0,0:3,0 0,18,173:6:0:0:5,1,0,0:6,0 +17 206 . G <*> 0 . DP=16;DPR=16,0;I16=12,4,0,0,577,21337,0,0,836,46564,0,0,269,5523,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,180:7:0:0:6,1,0,0:7,0 0,9,89:3:0:0:1,2,0,0:3,0 0,18,143:6:0:0:5,1,0,0:6,0 +17 207 . C <*> 0 . DP=16;DPR=16,0;I16=12,4,0,0,574,21076,0,0,836,46564,0,0,269,5547,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,179:7:0:0:6,1,0,0:7,0 0,9,93:3:0:0:1,2,0,0:3,0 0,18,151:6:0:0:5,1,0,0:6,0 +17 208 . A <*> 0 . DP=16;DPR=16,0;I16=12,4,0,0,576,21486,0,0,836,46564,0,0,268,5540,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,184:7:0:0:6,1,0,0:7,0 0,9,93:3:0:0:1,2,0,0:3,0 0,18,154:6:0:0:5,1,0,0:6,0 +17 209 . T <*> 0 . DP=16;DPR=16,0;I16=12,4,0,0,567,20475,0,0,836,46564,0,0,267,5551,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,173:7:0:0:6,1,0,0:7,0 0,9,91:3:0:0:1,2,0,0:3,0 0,18,146:6:0:0:5,1,0,0:6,0 +17 210 . C <*> 0 . DP=16;DPR=16,0;I16=12,4,0,0,577,21109,0,0,836,46564,0,0,266,5580,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,185:7:0:0:6,1,0,0:7,0 0,9,92:3:0:0:1,2,0,0:3,0 0,18,151:6:0:0:5,1,0,0:6,0 +17 211 . C <*> 0 . DP=16;DPR=16,0;I16=12,4,0,0,563,20227,0,0,836,46564,0,0,265,5627,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,172:7:0:0:6,1,0,0:7,0 0,9,92:3:0:0:1,2,0,0:3,0 0,18,153:6:0:0:5,1,0,0:6,0 +17 212 . C <*> 0 . DP=16;DPR=16,0;I16=12,4,0,0,589,22179,0,0,836,46564,0,0,263,5643,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,181:7:0:0:6,1,0,0:7,0 0,9,92:3:0:0:1,2,0,0:3,0 0,18,152:6:0:0:5,1,0,0:6,0 +17 213 . T <*> 0 . DP=16;DPR=16,0;I16=12,4,0,0,598,22838,0,0,836,46564,0,0,262,5678,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,181:7:0:0:6,1,0,0:7,0 0,9,95:3:0:0:1,2,0,0:3,0 0,18,165:6:0:0:5,1,0,0:6,0 +17 214 . A <*> 0 . DP=16;DPR=15,0;I16=11,4,0,0,529,19401,0,0,776,42964,0,0,240,5248,0,0;QS=3,0;MQSB=0.0161635;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,176:7:0:0:6,1,0,0:7,0 0,9,92:3:0:0:1,2,0,0:3,0 0,15,118:5:0:0:4,1,0,0:5,0 +17 215 . G <*> 0 . DP=15;DPR=15,0;I16=12,3,0,0,521,19073,0,0,807,45723,0,0,262,5754,0,0;QS=3,0;MQSB=0.0342181;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,185:7:0:0:6,1,0,0:7,0 0,9,90:3:0:0:1,2,0,0:3,0 0,15,105:5:0:0:5,0,0,0:5,0 +17 216 . A <*> 0 . DP=14;DPR=13,0;I16=10,3,0,0,464,16900,0,0,687,38523,0,0,238,5166,0,0;QS=3,0;MQSB=0.040184;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,173:7:0:0:6,1,0,0:7,0 0,9,92:3:0:0:1,2,0,0:3,0 0,9,81:3:0:0:3,0,0,0:3,0 +17 217 . A <*> 0 . DP=14;DPR=14,0;I16=11,3,0,0,515,19433,0,0,747,42123,0,0,264,5842,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,181:7:0:0:6,1,0,0:7,0 0,9,90:3:0:0:1,2,0,0:3,0 0,12,97:4:0:0:4,0,0,0:4,0 +17 218 . G <*> 0 . DP=14;DPR=14,0;I16=11,3,0,0,507,18957,0,0,747,42123,0,0,265,5907,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,178:7:0:0:6,1,0,0:7,0 0,9,90:3:0:0:1,2,0,0:3,0 0,12,110:4:0:0:4,0,0,0:4,0 +17 219 . T <*> 0 . DP=14;DPR=14,0;I16=11,3,0,0,470,16286,0,0,747,42123,0,0,266,5986,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,173:7:0:0:6,1,0,0:7,0 0,9,88:3:0:0:1,2,0,0:3,0 0,12,89:4:0:0:4,0,0,0:4,0 +17 220 . G <*> 0 . DP=14;DPR=13,0;I16=10,3,0,0,485,18307,0,0,687,38523,0,0,242,5454,0,0;QS=3,0;MQSB=0.040184;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,188:7:0:0:6,1,0,0:7,0 0,9,88:3:0:0:1,2,0,0:3,0 0,9,80:3:0:0:3,0,0,0:3,0 +17 221 . A <*> 0 . DP=14;DPR=14,0;I16=11,3,0,0,487,17615,0,0,747,42123,0,0,267,6135,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,176:7:0:0:6,1,0,0:7,0 0,9,88:3:0:0:1,2,0,0:3,0 0,12,101:4:0:0:4,0,0,0:4,0 +17 222 . A <*> 0 . DP=14;DPR=13,0;I16=10,3,0,0,465,17367,0,0,687,38523,0,0,242,5578,0,0;QS=3,0;MQSB=0.040184;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,186:7:0:0:6,1,0,0:7,0 0,9,85:3:0:0:1,2,0,0:3,0 0,9,69:3:0:0:3,0,0,0:3,0 +17 223 . G <*> 0 . DP=13;DPR=12,0;I16=9,3,0,0,405,14327,0,0,627,34923,0,0,243,5657,0,0;QS=3,0;MQSB=0.0443614;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,168:6:0:0:5,1,0,0:6,0 0,6,53:2:0:0:0,2,0,0:2,0 0,12,81:4:0:0:4,0,0,0:4,0 +17 224 . G <*> 0 . DP=12;DPR=12,0;I16=9,3,0,0,379,12759,0,0,627,34923,0,0,270,6370,0,0;QS=3,0;MQSB=0.0443614;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,168:6:0:0:5,1,0,0:6,0 0,6,50:2:0:0:0,2,0,0:2,0 0,12,70:4:0:0:4,0,0,0:4,0 +17 225 . C <*> 0 . DP=12;DPR=11,0;I16=8,3,0,0,382,13896,0,0,567,31323,0,0,261,6345,0,0;QS=3,0;MQSB=0.0497871;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,165:6:0:0:5,1,0,0:6,0 0,6,48:2:0:0:0,2,0,0:2,0 0,9,83:3:0:0:3,0,0,0:3,0 +17 226 . A <*> 0 . DP=13;DPR=11,0;I16=8,3,0,0,381,13669,0,0,567,31323,0,0,248,5894,0,0;QS=3,0;MQSB=0.0497871;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,166:6:0:0:5,1,0,0:6,0 0,6,53:2:0:0:0,2,0,0:2,0 0,9,84:3:0:0:3,0,0,0:3,0 +17 227 . C <*> 0 . DP=13;DPR=12,0;I16=8,4,0,0,406,14306,0,0,596,32164,0,0,267,6253,0,0;QS=3,0;MQSB=0.0249144;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,190:7:0:0:5,2,0,0:7,0 0,6,53:2:0:0:0,2,0,0:2,0 0,9,73:3:0:0:3,0,0,0:3,0 +17 228 . C <*> 0 . DP=13;DPR=13,0;I16=9,4,0,0,417,14381,0,0,656,35764,0,0,292,6884,0,0;QS=3,0;MQSB=0.0211283;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,187:7:0:0:5,2,0,0:7,0 0,6,45:2:0:0:0,2,0,0:2,0 0,12,96:4:0:0:4,0,0,0:4,0 +17 229 . G <*> 0 . DP=13;DPR=12,0;I16=9,3,0,0,358,11424,0,0,627,34923,0,0,270,6414,0,0;QS=3,0;MQSB=0.0443614;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,136:6:0:0:5,1,0,0:6,0 0,6,53:2:0:0:0,2,0,0:2,0 0,12,70:4:0:0:4,0,0,0:4,0 +17 230 . C <*> 0 . DP=13;DPR=13,0;I16=9,4,0,0,461,16861,0,0,656,35764,0,0,292,6920,0,0;QS=3,0;MQSB=0.0211283;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,186:7:0:0:5,2,0,0:7,0 0,6,53:2:0:0:0,2,0,0:2,0 0,12,100:4:0:0:4,0,0,0:4,0 +17 231 . C <*> 0 . DP=13;DPR=11,0;I16=7,4,0,0,414,15832,0,0,536,28564,0,0,247,5925,0,0;QS=3,0;MQSB=0.0401934;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,18,184:6:0:0:4,2,0,0:6,0 0,6,53:2:0:0:0,2,0,0:2,0 0,9,82:3:0:0:3,0,0,0:3,0 +17 232 . C <*> 0 . DP=14;DPR=13,0;I16=9,4,0,0,471,17371,0,0,656,35764,0,0,267,6363,0,0;QS=3,0;MQSB=0.0211283;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,198:7:0:0:5,2,0,0:7,0 0,6,53:2:0:0:0,2,0,0:2,0 0,12,101:4:0:0:4,0,0,0:4,0 +17 233 . A <*> 0 . DP=14;DPR=14,0;I16=10,4,0,0,496,18142,0,0,716,39364,0,0,292,6984,0,0;QS=3,0;MQSB=0.0183156;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,192:7:0:0:5,2,0,0:7,0 0,6,53:2:0:0:0,2,0,0:2,0 0,15,119:5:0:0:5,0,0,0:5,0 +17 234 . A <*> 0 . DP=14;DPR=14,0;I16=10,4,0,0,502,18390,0,0,716,39364,0,0,292,6988,0,0;QS=3,0;MQSB=0.0183156;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,185:7:0:0:5,2,0,0:7,0 0,6,53:2:0:0:0,2,0,0:2,0 0,15,123:5:0:0:5,0,0,0:5,0 +17 235 . A <*> 0 . DP=14;DPR=13,0;I16=9,4,0,0,476,17652,0,0,656,35764,0,0,267,6375,0,0;QS=3,0;MQSB=0.0211283;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,21,186:7:0:0:5,2,0,0:7,0 0,6,53:2:0:0:0,2,0,0:2,0 0,12,111:4:0:0:4,0,0,0:4,0 +17 236 . G <*> 0 . DP=15;DPR=15,0;I16=11,4,0,0,501,17481,0,0,776,42964,0,0,290,6924,0,0;QS=3,0;MQSB=0.0161635;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,24,206:8:0:0:6,2,0,0:8,0 0,6,53:2:0:0:0,2,0,0:2,0 0,15,103:5:0:0:5,0,0,0:5,0 +17 237 . A <*> 0 . DP=14;DPR=13,0;I16=9,4,0,0,465,16877,0,0,656,35764,0,0,266,6282,0,0;QS=3,0;MQSB=0.0211283;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,24,206:8:0:0:6,2,0,0:8,0 0,6,53:2:0:0:0,2,0,0:2,0 0,9,92:3:0:0:3,0,0,0:3,0 +17 238 . C <*> 0 . DP=14;DPR=14,0;I16=10,4,0,0,482,17238,0,0,716,39364,0,0,292,6900,0,0;QS=3,0;MQSB=0.0183156;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,24,211:8:0:0:6,2,0,0:8,0 0,6,53:2:0:0:0,2,0,0:2,0 0,12,82:4:0:0:4,0,0,0:4,0 +17 239 . A <*> 0 . DP=15;DPR=15,0;I16=10,5,0,0,525,19155,0,0,776,42964,0,0,292,6852,0,0;QS=3,0;MQSB=0.0497871;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,27,223:9:0:0:6,3,0,0:9,0 0,6,50:2:0:0:0,2,0,0:2,0 0,12,108:4:0:0:4,0,0,0:4,0 +17 240 . C <*> 0 . DP=15;DPR=15,0;I16=10,5,0,0,512,17930,0,0,776,42964,0,0,292,6764,0,0;QS=3,0;MQSB=0.0497871;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,27,220:9:0:0:6,3,0,0:9,0 0,6,53:2:0:0:0,2,0,0:2,0 0,12,106:4:0:0:4,0,0,0:4,0 +17 241 . G <*> 0 . DP=15;DPR=14,0;I16=9,5,0,0,444,14636,0,0,716,39364,0,0,269,6159,0,0;QS=3,0;MQSB=0.0561348;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,27,203:9:0:0:6,3,0,0:9,0 0,6,53:2:0:0:0,2,0,0:2,0 0,9,59:3:0:0:3,0,0,0:3,0 +17 242 . C <*> 0 . DP=15;DPR=15,0;I16=10,5,0,0,555,21177,0,0,776,42964,0,0,292,6624,0,0;QS=3,0;MQSB=0.0497871;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,27,242:9:0:0:6,3,0,0:9,0 0,6,53:2:0:0:0,2,0,0:2,0 0,12,94:4:0:0:4,0,0,0:4,0 +17 243 . C <*> 0 . DP=16;DPR=14,0;I16=9,5,0,0,523,19737,0,0,716,39364,0,0,284,6508,0,0;QS=3,0;MQSB=0.0561348;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,24,220:8:0:0:5,3,0,0:8,0 0,6,53:2:0:0:0,2,0,0:2,0 0,12,104:4:0:0:4,0,0,0:4,0 +17 244 . C <*> 0 . DP=16;DPR=16,0;I16=10,6,0,0,620,24272,0,0,805,43805,0,0,298,6568,0,0;QS=3,0;MQSB=0.0253122;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,27,245:9:0:0:6,3,0,0:9,0 0,9,72:3:0:0:0,3,0,0:3,0 0,12,106:4:0:0:4,0,0,0:4,0 +17 245 . A <*> 0 . DP=17;DPR=17,0;I16=10,7,0,0,649,24843,0,0,865,47405,0,0,299,6553,0,0;QS=3,0;MQSB=0.0509867;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,27,236:9:0:0:6,3,0,0:9,0 0,12,93:4:0:0:0,4,0,0:4,0 0,12,115:4:0:0:4,0,0,0:4,0 +17 246 . T <*> 0 . DP=18;DPR=18,0;I16=10,8,0,0,649,23833,0,0,894,48246,0,0,301,6553,0,0;QS=3,0;MQSB=0.0286491;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,247:10:0:0:6,4,0,0:10,0 0,12,94:4:0:0:0,4,0,0:4,0 0,12,98:4:0:0:4,0,0,0:4,0 +17 247 . G <*> 0 . DP=18;DPR=18,0;I16=10,8,0,0,642,23610,0,0,894,48246,0,0,304,6570,0,0;QS=3,0;MQSB=0.0286491;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,252:10:0:0:6,4,0,0:10,0 0,12,83:4:0:0:0,4,0,0:4,0 0,12,103:4:0:0:4,0,0,0:4,0 +17 248 . T <*> 0 . DP=18;DPR=18,0;I16=10,8,0,0,636,22944,0,0,894,48246,0,0,307,6605,0,0;QS=3,0;MQSB=0.0286491;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,234:10:0:0:6,4,0,0:10,0 0,12,86:4:0:0:0,4,0,0:4,0 0,12,114:4:0:0:4,0,0,0:4,0 +17 249 . C <*> 0 . DP=18;DPR=18,0;I16=10,8,0,0,656,24846,0,0,894,48246,0,0,310,6658,0,0;QS=3,0;MQSB=0.0286491;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,253:10:0:0:6,4,0,0:10,0 0,12,79:4:0:0:0,4,0,0:4,0 0,12,112:4:0:0:4,0,0,0:4,0 +17 250 . C <*> 0 . DP=19;DPR=19,0;I16=10,9,0,0,694,26160,0,0,923,49087,0,0,311,6631,0,0;QS=3,0;MQSB=0.0168512;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,248:10:0:0:6,4,0,0:10,0 0,12,89:4:0:0:0,4,0,0:4,0 0,15,142:5:0:0:4,1,0,0:5,0 +17 251 . A <*> 0 . DP=19;DPR=18,0;I16=9,9,0,0,688,26506,0,0,863,45487,0,0,313,6627,0,0;QS=3,0;MQSB=0.0208913;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,27,233:9:0:0:5,4,0,0:9,0 0,12,97:4:0:0:0,4,0,0:4,0 0,15,148:5:0:0:4,1,0,0:5,0 +17 252 . G <*> 0 . DP=18;DPR=17,0;I16=8,9,0,0,641,24631,0,0,803,41887,0,0,304,6502,0,0;QS=3,0;MQSB=0.026526;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,27,243:9:0:0:5,4,0,0:9,0 0,12,91:4:0:0:0,4,0,0:4,0 0,12,121:4:0:0:3,1,0,0:4,0 +17 253 . C <*> 0 . DP=19;DPR=19,0;I16=9,10,0,0,705,26921,0,0,892,46328,0,0,319,6687,0,0;QS=3,0;MQSB=0.0132999;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,27,247:9:0:0:5,4,0,0:9,0 0,12,86:4:0:0:0,4,0,0:4,0 0,18,155:6:0:0:4,2,0,0:6,0 +17 254 . T <*> 0 . DP=20;DPR=19,0;I16=10,9,0,0,719,27517,0,0,892,46328,0,0,314,6670,0,0;QS=3,0;MQSB=0.00482795;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,254:10:0:0:6,4,0,0:10,0 0,9,72:3:0:0:0,3,0,0:3,0 0,18,164:6:0:0:4,2,0,0:6,0 +17 255 . T <*> 0 . DP=21;DPR=21,0;I16=11,10,0,0,750,27076,0,0,1012,53528,0,0,328,6840,0,0;QS=3,0;MQSB=0.00822975;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,241:11:0:0:7,4,0,0:11,0 0,12,95:4:0:0:0,4,0,0:4,0 0,18,161:6:0:0:4,2,0,0:6,0 +17 256 . A <*> 0 . DP=22;DPR=22,0;I16=11,11,0,0,811,30063,0,0,1049,54897,0,0,334,6956,0,0;QS=3,0;MQSB=0.00507916;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:7,4,0,0:11,0 0,15,110:5:0:0:0,5,0,0:5,0 0,18,166:6:0:0:4,2,0,0:6,0 +17 257 . T <*> 0 . DP=22;DPR=22,0;I16=11,11,0,0,814,30420,0,0,1049,54897,0,0,341,7101,0,0;QS=3,0;MQSB=0.00507916;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,247:11:0:0:7,4,0,0:11,0 0,15,113:5:0:0:0,5,0,0:5,0 0,18,168:6:0:0:4,2,0,0:6,0 +17 258 . T <*> 0 . DP=22;DPR=22,0;I16=11,11,0,0,791,28943,0,0,1049,54897,0,0,347,7225,0,0;QS=3,0;MQSB=0.00507916;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,254:11:0:0:7,4,0,0:11,0 0,15,116:5:0:0:0,5,0,0:5,0 0,18,155:6:0:0:4,2,0,0:6,0 +17 259 . C <*> 0 . DP=22;DPR=21,0;I16=11,10,0,0,785,29809,0,0,1020,54056,0,0,332,6936,0,0;QS=3,0;MQSB=0.00822975;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:7,4,0,0:11,0 0,12,90:4:0:0:0,4,0,0:4,0 0,18,170:6:0:0:4,2,0,0:6,0 +17 260 . T <*> 0 . DP=21;DPR=21,0;I16=10,11,0,0,829,32899,0,0,989,51297,0,0,360,7556,0,0;QS=3,0;MQSB=0.00660016;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:7,4,0,0:11,0 0,15,118:5:0:0:0,5,0,0:5,0 0,15,156:5:0:0:3,2,0,0:5,0 +17 261 . G <*> 0 . DP=21;DPR=21,0;I16=10,11,0,0,735,27379,0,0,989,51297,0,0,367,7761,0,0;QS=3,0;MQSB=0.00660016;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,254:11:0:0:7,4,0,0:11,0 0,15,111:5:0:0:0,5,0,0:5,0 0,15,122:5:0:0:3,2,0,0:5,0 +17 262 . C <*> 0 . DP=22;DPR=22,0;I16=10,12,0,0,806,30278,0,0,1049,54897,0,0,373,7941,0,0;QS=3,0;MQSB=0.0122507;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:7,4,0,0:11,0 0,15,99:5:0:0:0,5,0,0:5,0 0,18,164:6:0:0:3,3,0,0:6,0 +17 263 . C <*> 0 . DP=22;DPR=22,0;I16=10,12,0,0,799,29717,0,0,1049,54897,0,0,380,8146,0,0;QS=3,0;MQSB=0.0122507;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:7,4,0,0:11,0 0,15,98:5:0:0:0,5,0,0:5,0 0,18,168:6:0:0:3,3,0,0:6,0 +17 264 . C <*> 0 . DP=22;DPR=22,0;I16=10,12,0,0,821,31325,0,0,1049,54897,0,0,386,8326,0,0;QS=3,0;MQSB=0.0122507;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:7,4,0,0:11,0 0,15,104:5:0:0:0,5,0,0:5,0 0,18,172:6:0:0:3,3,0,0:6,0 +17 265 . A <*> 0 . DP=21;DPR=21,0;I16=9,12,0,0,800,31906,0,0,989,51297,0,0,390,8380,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:7,4,0,0:11,0 0,15,114:5:0:0:0,5,0,0:5,0 0,15,129:5:0:0:2,3,0,0:5,0 +17 266 . G <*> 0 . DP=21;DPR=20,0;I16=9,11,0,0,747,28155,0,0,960,50456,0,0,369,7833,0,0;QS=3,0;MQSB=0.0237479;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:7,4,0,0:11,0 0,12,97:4:0:0:0,4,0,0:4,0 0,15,138:5:0:0:2,3,0,0:5,0 +17 267 . T <*> 0 . DP=21;DPR=20,0;I16=9,11,0,0,739,27465,0,0,960,50456,0,0,373,7935,0,0;QS=3,0;MQSB=0.0237479;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,254:11:0:0:7,4,0,0:11,0 0,12,101:4:0:0:0,4,0,0:4,0 0,15,149:5:0:0:2,3,0,0:5,0 +17 268 . T <*> 0 . DP=21;DPR=21,0;I16=9,12,0,0,748,27708,0,0,989,51297,0,0,402,8686,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,238:11:0:0:7,4,0,0:11,0 0,15,110:5:0:0:0,5,0,0:5,0 0,15,156:5:0:0:2,3,0,0:5,0 +17 269 . C <*> 0 . DP=22;DPR=21,0;I16=9,12,0,0,764,28632,0,0,989,51297,0,0,381,8211,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,36,255:12:0:0:7,5,0,0:12,0 0,12,91:4:0:0:0,4,0,0:4,0 0,15,154:5:0:0:2,3,0,0:5,0 +17 270 . C <*> 0 . DP=22;DPR=21,0;I16=9,12,0,0,758,28146,0,0,989,51297,0,0,385,8337,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,36,255:12:0:0:7,5,0,0:12,0 0,12,96:4:0:0:0,4,0,0:4,0 0,15,143:5:0:0:2,3,0,0:5,0 +17 271 . T <*> 0 . DP=22;DPR=22,0;I16=9,13,0,0,847,32935,0,0,1018,52138,0,0,413,9065,0,0;QS=3,0;MQSB=0.0109431;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,36,255:12:0:0:7,5,0,0:12,0 0,15,113:5:0:0:0,5,0,0:5,0 0,15,152:5:0:0:2,3,0,0:5,0 +17 272 . C <*> 0 . DP=22;DPR=21,0;I16=9,12,0,0,809,31413,0,0,989,51297,0,0,390,8518,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,36,255:12:0:0:7,5,0,0:12,0 0,12,96:4:0:0:0,4,0,0:4,0 0,15,149:5:0:0:2,3,0,0:5,0 +17 273 . T <*> 0 . DP=22;DPR=21,0;I16=9,12,0,0,798,30664,0,0,989,51297,0,0,392,8620,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,36,255:12:0:0:7,5,0,0:12,0 0,12,95:4:0:0:0,4,0,0:4,0 0,15,161:5:0:0:2,3,0,0:5,0 +17 274 . C <*> 0 . DP=22;DPR=21,0;I16=9,12,0,0,763,28177,0,0,989,51297,0,0,394,8746,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,36,255:12:0:0:7,5,0,0:12,0 0,12,101:4:0:0:0,4,0,0:4,0 0,15,144:5:0:0:2,3,0,0:5,0 +17 275 . C <*> 0 . DP=20;DPR=20,0;I16=7,13,0,0,768,29994,0,0,898,44938,0,0,423,9519,0,0;QS=3,0;MQSB=0.0213617;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:6,5,0,0:11,0 0,15,114:5:0:0:0,5,0,0:5,0 0,12,122:4:0:0:1,3,0,0:4,0 +17 276 . A <*> 0 . DP=20;DPR=20,0;I16=7,13,0,0,805,32931,0,0,898,44938,0,0,424,9538,0,0;QS=3,0;MQSB=0.0213617;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,253:11:0:0:6,5,0,0:11,0 0,15,122:5:0:0:0,5,0,0:5,0 0,12,124:4:0:0:1,3,0,0:4,0 +17 277 . G <*> 0 . DP=20;DPR=20,0;I16=7,13,0,0,764,29732,0,0,898,44938,0,0,425,9579,0,0;QS=3,0;MQSB=0.0213617;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:6,5,0,0:11,0 0,15,114:5:0:0:0,5,0,0:5,0 0,12,121:4:0:0:1,3,0,0:4,0 +17 278 . A <*> 0 . DP=21;DPR=20,0;I16=6,14,0,0,722,26452,0,0,867,42179,0,0,415,9521,0,0;QS=3,0;MQSB=0.0246228;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,238:10:0:0:5,5,0,0:10,0 0,18,123:6:0:0:0,6,0,0:6,0 0,12,121:4:0:0:1,3,0,0:4,0 +17 279 . A <*> 0 . DP=22;DPR=22,0;I16=7,15,0,0,786,28694,0,0,956,46620,0,0,427,9677,0,0;QS=3,0;MQSB=0.0124927;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,36,255:12:0:0:6,6,0,0:12,0 0,18,123:6:0:0:0,6,0,0:6,0 0,12,122:4:0:0:1,3,0,0:4,0 +17 280 . A <*> 0 . DP=22;DPR=22,0;I16=7,15,0,0,815,31561,0,0,956,46620,0,0,428,9684,0,0;QS=3,0;MQSB=0.0124927;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,36,253:12:0:0:6,6,0,0:12,0 0,18,130:6:0:0:0,6,0,0:6,0 0,12,129:4:0:0:1,3,0,0:4,0 +17 281 . G <*> 0 . DP=22;DPR=22,0;I16=7,15,0,0,820,31416,0,0,956,46620,0,0,428,9662,0,0;QS=3,0;MQSB=0.0124927;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,36,255:12:0:0:6,6,0,0:12,0 0,18,122:6:0:0:0,6,0,0:6,0 0,12,123:4:0:0:1,3,0,0:4,0 +17 282 . G <*> 0 . DP=22;DPR=22,0;I16=7,15,0,0,806,30420,0,0,956,46620,0,0,427,9609,0,0;QS=3,0;MQSB=0.0124927;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,36,253:12:0:0:6,6,0,0:12,0 0,18,124:6:0:0:0,6,0,0:6,0 0,12,119:4:0:0:1,3,0,0:4,0 +17 283 . C <*> 0 . DP=23;DPR=22,0;I16=7,15,0,0,827,31785,0,0,956,46620,0,0,426,9574,0,0;QS=3,0;MQSB=0.0124927;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,36,255:12:0:0:6,6,0,0:12,0 0,18,125:6:0:0:0,6,0,0:6,0 0,12,122:4:0:0:1,3,0,0:4,0 +17 284 . T <*> 0 . DP=23;DPR=23,0;I16=7,16,0,0,901,35479,0,0,1016,50220,0,0,431,9593,0,0;QS=3,0;MQSB=0.0194969;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,36,255:12:0:0:6,6,0,0:12,0 0,18,126:6:0:0:0,6,0,0:6,0 0,15,144:5:0:0:1,4,0,0:5,0 +17 285 . G <*> 0 . DP=23;DPR=23,0;I16=7,16,0,0,860,32856,0,0,1016,50220,0,0,431,9607,0,0;QS=3,0;MQSB=0.0194969;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,36,255:12:0:0:6,6,0,0:12,0 0,18,119:6:0:0:0,6,0,0:6,0 0,15,132:5:0:0:1,4,0,0:5,0 +17 286 . C <*> 0 . DP=24;DPR=24,0;I16=8,16,0,0,875,32883,0,0,1076,53820,0,0,431,9641,0,0;QS=3,0;MQSB=0.0132999;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,36,255:12:0:0:6,6,0,0:12,0 0,21,150:7:0:0:1,6,0,0:7,0 0,15,134:5:0:0:1,4,0,0:5,0 +17 287 . A <*> 0 . DP=25;DPR=25,0;I16=9,16,0,0,895,32957,0,0,1136,57420,0,0,432,9696,0,0;QS=3,0;MQSB=0.00934348;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,36,255:12:0:0:6,6,0,0:12,0 0,24,178:8:0:0:2,6,0,0:8,0 0,15,133:5:0:0:1,4,0,0:5,0 +17 288 . T <*> 0 . DP=25;DPR=25,0;I16=9,16,0,0,931,35011,0,0,1136,57420,0,0,432,9674,0,0;QS=3,0;MQSB=0.00934348;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,36,255:12:0:0:6,6,0,0:12,0 0,24,184:8:0:0:2,6,0,0:8,0 0,15,146:5:0:0:1,4,0,0:5,0 +17 289 . G <*> 0 . DP=25;DPR=25,0;I16=9,16,0,0,939,36117,0,0,1136,57420,0,0,432,9676,0,0;QS=3,0;MQSB=0.00934348;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,36,255:12:0:0:6,6,0,0:12,0 0,24,185:8:0:0:2,6,0,0:8,0 0,15,136:5:0:0:1,4,0,0:5,0 +17 290 . G <*> 0 . DP=23;DPR=23,0;I16=8,15,0,0,805,29157,0,0,1047,52979,0,0,433,9651,0,0;QS=3,0;MQSB=0.0177152;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,240:11:0:0:5,6,0,0:11,0 0,21,164:7:0:0:2,5,0,0:7,0 0,15,126:5:0:0:1,4,0,0:5,0 +17 291 . T <*> 0 . DP=24;DPR=23,0;I16=8,15,0,0,840,31616,0,0,1047,52979,0,0,421,9479,0,0;QS=3,0;MQSB=0.0177152;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,244:11:0:0:5,6,0,0:11,0 0,21,168:7:0:0:2,5,0,0:7,0 0,15,136:5:0:0:1,4,0,0:5,0 +17 292 . T <*> 0 . DP=25;DPR=25,0;I16=9,16,0,0,888,32274,0,0,1167,60179,0,0,436,9668,0,0;QS=3,0;MQSB=0.0197089;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,253:11:0:0:5,6,0,0:11,0 0,24,181:8:0:0:3,5,0,0:8,0 0,18,156:6:0:0:1,5,0,0:6,0 +17 293 . G <*> 0 . DP=26;DPR=25,0;I16=10,15,0,0,934,35232,0,0,1167,60179,0,0,424,9488,0,0;QS=3,0;MQSB=0.0095249;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,36,255:12:0:0:6,6,0,0:12,0 0,24,196:8:0:0:3,5,0,0:8,0 0,15,145:5:0:0:1,4,0,0:5,0 +17 294 . A <*> 0 . DP=26;DPR=26,0;I16=10,16,0,0,931,33937,0,0,1227,63779,0,0,443,9785,0,0;QS=3,0;MQSB=0.0149748;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,36,252:12:0:0:6,6,0,0:12,0 0,24,201:8:0:0:3,5,0,0:8,0 0,18,161:6:0:0:1,5,0,0:6,0 +17 295 . C <*> 0 . DP=25;DPR=24,0;I16=10,14,0,0,897,33973,0,0,1169,62097,0,0,430,9544,0,0;QS=3,0;MQSB=0.0310726;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:6,5,0,0:11,0 0,21,180:7:0:0:3,4,0,0:7,0 0,18,159:6:0:0:1,5,0,0:6,0 +17 296 . A <*> 0 . DP=25;DPR=25,0;I16=10,15,0,0,874,31846,0,0,1198,62938,0,0,451,9905,0,0;QS=3,0;MQSB=0.0213617;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:6,5,0,0:11,0 0,24,169:8:0:0:3,5,0,0:8,0 0,18,169:6:0:0:1,5,0,0:6,0 +17 297 . C <*> 0 . DP=25;DPR=24,0;I16=9,15,0,0,901,34305,0,0,1138,59338,0,0,445,9901,0,0;QS=3,0;MQSB=0.0273237;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:6,5,0,0:11,0 0,21,174:7:0:0:2,5,0,0:7,0 0,18,161:6:0:0:1,5,0,0:6,0 +17 298 . A <*> 0 . DP=26;DPR=26,0;I16=11,15,0,0,936,34652,0,0,1258,66538,0,0,459,10121,0,0;QS=3,0;MQSB=0.017008;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:6,5,0,0:11,0 0,24,184:8:0:0:3,5,0,0:8,0 0,21,191:7:0:0:2,5,0,0:7,0 +17 299 . C <*> 0 . DP=27;DPR=26,0;I16=11,15,0,0,971,36863,0,0,1258,66538,0,0,464,10266,0,0;QS=3,0;MQSB=0.017008;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:6,5,0,0:11,0 0,24,193:8:0:0:3,5,0,0:8,0 0,21,189:7:0:0:2,5,0,0:7,0 +17 300 . A <*> 0 . DP=27;DPR=26,0;I16=11,15,0,0,1001,39455,0,0,1258,66538,0,0,469,10437,0,0;QS=3,0;MQSB=0.017008;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:6,5,0,0:11,0 0,24,204:8:0:0:3,5,0,0:8,0 0,21,210:7:0:0:2,5,0,0:7,0 +17 301 . G <*> 0 . DP=25;DPR=24,0;I16=10,14,0,0,928,36116,0,0,1169,62097,0,0,476,10632,0,0;QS=3,0;MQSB=0.0310726;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,255:10:0:0:5,5,0,0:10,0 0,21,195:7:0:0:3,4,0,0:7,0 0,21,196:7:0:0:2,5,0,0:7,0 +17 302 . T <*> 0 . DP=25;DPR=24,0;I16=10,14,0,0,879,32885,0,0,1169,62097,0,0,483,10849,0,0;QS=3,0;MQSB=0.0310726;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,231:10:0:0:5,5,0,0:10,0 0,21,172:7:0:0:3,4,0,0:7,0 0,21,202:7:0:0:2,5,0,0:7,0 +17 302 . T TA 0 . INDEL;IDV=7;IMF=1;DP=25;DPR=6,19;I16=2,4,8,11,214,7674,793,33369,236,10564,993,55133,109,2229,377,8629;QS=0.511212,2.48879;VDB=0.27613;SGB=-4.22417;MQSB=0.0443614;MQ0F=0 PL:DP:DV:SP:DP4:DPR 167,0,96:11:6:6:1,4,4,2:5,6 157,0,9:7:6:0:1,0,2,4:1,6 201,21,0:7:7:0:0,0,2,5:0,7 +17 303 . G <*> 0 . DP=25;DPR=25,0;I16=10,15,0,0,976,38516,0,0,1229,65697,0,0,497,11181,0,0;QS=3,0;MQSB=0.0443614;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:5,6,0,0:11,0 0,21,197:7:0:0:3,4,0,0:7,0 0,21,195:7:0:0:2,5,0,0:7,0 +17 304 . C <*> 0 . DP=27;DPR=27,0;I16=11,16,0,0,991,37005,0,0,1318,70138,0,0,503,11359,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:5,6,0,0:11,0 0,24,206:8:0:0:4,4,0,0:8,0 0,24,200:8:0:0:2,6,0,0:8,0 +17 305 . C <*> 0 . DP=27;DPR=27,0;I16=11,16,0,0,1057,41761,0,0,1318,70138,0,0,510,11508,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:5,6,0,0:11,0 0,24,213:8:0:0:4,4,0,0:8,0 0,24,211:8:0:0:2,6,0,0:8,0 +17 306 . T <*> 0 . DP=27;DPR=27,0;I16=11,16,0,0,1033,40253,0,0,1318,70138,0,0,517,11679,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:5,6,0,0:11,0 0,24,207:8:0:0:4,4,0,0:8,0 0,24,217:8:0:0:2,6,0,0:8,0 +17 307 . G <*> 0 . DP=27;DPR=26,0;I16=11,15,0,0,984,37886,0,0,1289,69297,0,0,498,11198,0,0;QS=3,0;MQSB=0.174566;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:5,6,0,0:11,0 0,21,189:7:0:0:4,3,0,0:7,0 0,24,203:8:0:0:2,6,0,0:8,0 +17 308 . C <*> 0 . DP=27;DPR=27,0;I16=11,16,0,0,892,30810,0,0,1318,70138,0,0,529,11991,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:5,6,0,0:11,0 0,24,178:8:0:0:4,4,0,0:8,0 0,24,185:8:0:0:2,6,0,0:8,0 +17 309 . G <*> 0 . DP=27;DPR=27,0;I16=11,16,0,0,951,34599,0,0,1318,70138,0,0,535,12183,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,243:11:0:0:5,6,0,0:11,0 0,24,183:8:0:0:4,4,0,0:8,0 0,24,205:8:0:0:2,6,0,0:8,0 +17 310 . A <*> 0 . DP=27;DPR=27,0;I16=11,16,0,0,1001,38063,0,0,1318,70138,0,0,540,12350,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:5,6,0,0:11,0 0,24,200:8:0:0:4,4,0,0:8,0 0,24,217:8:0:0:2,6,0,0:8,0 +17 311 . C <*> 0 . DP=27;DPR=27,0;I16=11,16,0,0,1037,40263,0,0,1318,70138,0,0,544,12492,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:5,6,0,0:11,0 0,24,215:8:0:0:4,4,0,0:8,0 0,24,210:8:0:0:2,6,0,0:8,0 +17 312 . A <*> 0 . DP=26;DPR=26,0;I16=10,16,0,0,985,38043,0,0,1258,66538,0,0,549,12657,0,0;QS=3,0;MQSB=0.157183;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,237:10:0:0:4,6,0,0:10,0 0,24,215:8:0:0:4,4,0,0:8,0 0,24,218:8:0:0:2,6,0,0:8,0 +17 313 . A <*> 0 . DP=26;DPR=26,0;I16=10,16,0,0,983,37969,0,0,1258,66538,0,0,551,12695,0,0;QS=3,0;MQSB=0.157183;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,235:10:0:0:4,6,0,0:10,0 0,24,219:8:0:0:4,4,0,0:8,0 0,24,215:8:0:0:2,6,0,0:8,0 +17 314 . A <*> 0 . DP=27;DPR=27,0;I16=10,17,0,0,1050,41798,0,0,1318,70138,0,0,553,12757,0,0;QS=3,0;MQSB=0.195223;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,250:11:0:0:4,7,0,0:11,0 0,24,217:8:0:0:4,4,0,0:8,0 0,24,227:8:0:0:2,6,0,0:8,0 +17 315 . G <*> 0 . DP=26;DPR=26,0;I16=10,16,0,0,1025,40941,0,0,1289,69297,0,0,557,12843,0,0;QS=3,0;MQSB=0.252051;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,252:10:0:0:4,6,0,0:10,0 0,24,216:8:0:0:4,4,0,0:8,0 0,24,225:8:0:0:2,6,0,0:8,0 +17 316 . C <*> 0 . DP=27;DPR=25,0;I16=10,15,0,0,983,39393,0,0,1252,67928,0,0,535,12277,0,0;QS=3,0;MQSB=0.312403;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,255:10:0:0:4,6,0,0:10,0 0,21,183:7:0:0:4,3,0,0:7,0 0,24,224:8:0:0:2,6,0,0:8,0 +17 317 . T <*> 0 . DP=27;DPR=26,0;I16=10,16,0,0,1028,41392,0,0,1320,72056,0,0,547,12557,0,0;QS=3,0;MQSB=0.377061;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,255:10:0:0:4,6,0,0:10,0 0,24,230:8:0:0:4,4,0,0:8,0 0,24,206:8:0:0:2,6,0,0:8,0 +17 318 . G <*> 0 . DP=27;DPR=27,0;I16=10,17,0,0,1038,40546,0,0,1349,72897,0,0,570,13018,0,0;QS=3,0;MQSB=0.297797;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,249:10:0:0:4,6,0,0:10,0 0,27,235:9:0:0:4,5,0,0:9,0 0,24,208:8:0:0:2,6,0,0:8,0 +17 319 . A <*> 0 . DP=27;DPR=26,0;I16=9,17,0,0,994,38654,0,0,1289,69297,0,0,560,12906,0,0;QS=3,0;MQSB=0.346864;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,249:10:0:0:4,6,0,0:10,0 0,27,228:9:0:0:4,5,0,0:9,0 0,21,185:7:0:0:1,6,0,0:7,0 +17 320 . A <*> 0 . DP=27;DPR=27,0;I16=10,17,0,0,1022,39418,0,0,1349,72897,0,0,573,13053,0,0;QS=3,0;MQSB=0.297797;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,247:10:0:0:4,6,0,0:10,0 0,27,230:9:0:0:4,5,0,0:9,0 0,24,211:8:0:0:2,6,0,0:8,0 +17 321 . T <*> 0 . DP=27;DPR=27,0;I16=10,17,0,0,1026,39772,0,0,1349,72897,0,0,573,13029,0,0;QS=3,0;MQSB=0.297797;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,253:10:0:0:4,6,0,0:10,0 0,27,214:9:0:0:4,5,0,0:9,0 0,24,218:8:0:0:2,6,0,0:8,0 +17 322 . G <*> 0 . DP=28;DPR=28,0;I16=10,18,0,0,1091,43151,0,0,1409,76497,0,0,573,13029,0,0;QS=3,0;MQSB=0.343265;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,255:10:0:0:4,6,0,0:10,0 0,27,226:9:0:0:4,5,0,0:9,0 0,27,223:9:0:0:2,7,0,0:9,0 +17 323 . C <*> 0 . DP=28;DPR=27,0;I16=9,18,0,0,1067,42619,0,0,1349,72897,0,0,565,12939,0,0;QS=3,0;MQSB=0.394987;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,255:10:0:0:4,6,0,0:10,0 0,27,225:9:0:0:4,5,0,0:9,0 0,24,198:8:0:0:1,7,0,0:8,0 +17 324 . T <*> 0 . DP=30;DPR=30,0;I16=12,18,0,0,1145,44221,0,0,1529,83697,0,0,573,13001,0,0;QS=3,0;MQSB=0.264959;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,253:10:0:0:4,6,0,0:10,0 0,27,237:9:0:0:4,5,0,0:9,0 0,33,255:11:0:0:4,7,0,0:11,0 +17 325 . A <*> 0 . DP=31;DPR=31,0;I16=13,18,0,0,1132,42058,0,0,1589,87297,0,0,573,12925,0,0;QS=3,0;MQSB=0.235201;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:5,6,0,0:11,0 0,27,208:9:0:0:4,5,0,0:9,0 0,33,255:11:0:0:4,7,0,0:11,0 +17 326 . T <*> 0 . DP=31;DPR=31,0;I16=13,18,0,0,1157,44193,0,0,1589,87297,0,0,574,12878,0,0;QS=3,0;MQSB=0.235201;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:5,6,0,0:11,0 0,27,216:9:0:0:4,5,0,0:9,0 0,33,255:11:0:0:4,7,0,0:11,0 +17 327 . C <*> 0 . DP=31;DPR=31,0;I16=13,18,0,0,1147,43895,0,0,1589,87297,0,0,575,12861,0,0;QS=3,0;MQSB=0.235201;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:5,6,0,0:11,0 0,27,198:9:0:0:4,5,0,0:9,0 0,33,255:11:0:0:4,7,0,0:11,0 +17 328 . A <*> 0 . DP=31;DPR=31,0;I16=13,18,0,0,1167,44531,0,0,1589,87297,0,0,574,12776,0,0;QS=3,0;MQSB=0.235201;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:5,6,0,0:11,0 0,27,226:9:0:0:4,5,0,0:9,0 0,33,255:11:0:0:4,7,0,0:11,0 +17 329 . T <*> 0 . DP=31;DPR=31,0;I16=13,18,0,0,1210,47742,0,0,1589,87297,0,0,572,12676,0,0;QS=3,0;MQSB=0.235201;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:5,6,0,0:11,0 0,27,237:9:0:0:4,5,0,0:9,0 0,33,255:11:0:0:4,7,0,0:11,0 +17 330 . T <*> 0 . DP=31;DPR=31,0;I16=13,18,0,0,1185,45839,0,0,1589,87297,0,0,568,12510,0,0;QS=3,0;MQSB=0.235201;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,254:11:0:0:5,6,0,0:11,0 0,27,231:9:0:0:4,5,0,0:9,0 0,33,255:11:0:0:4,7,0,0:11,0 +17 331 . T <*> 0 . DP=32;DPR=32,0;I16=14,18,0,0,1154,42510,0,0,1649,90897,0,0,563,12327,0,0;QS=3,0;MQSB=0.210122;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:5,6,0,0:11,0 0,27,222:9:0:0:4,5,0,0:9,0 0,36,255:12:0:0:5,7,0,0:12,0 +17 332 . A <*> 0 . DP=32;DPR=32,0;I16=14,18,0,0,1156,42666,0,0,1649,90897,0,0,560,12178,0,0;QS=3,0;MQSB=0.210122;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,36,255:12:0:0:6,6,0,0:12,0 0,27,214:9:0:0:4,5,0,0:9,0 0,33,255:11:0:0:4,7,0,0:11,0 +17 333 . A <*> 0 . DP=32;DPR=32,0;I16=14,18,0,0,1141,41987,0,0,1649,90897,0,0,558,12064,0,0;QS=3,0;MQSB=0.210122;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,36,255:12:0:0:6,6,0,0:12,0 0,27,223:9:0:0:4,5,0,0:9,0 0,33,255:11:0:0:4,7,0,0:11,0 +17 334 . A <*> 0 . DP=32;DPR=32,0;I16=14,18,0,0,1162,43328,0,0,1649,90897,0,0,556,11986,0,0;QS=3,0;MQSB=0.210122;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,36,255:12:0:0:6,6,0,0:12,0 0,27,221:9:0:0:4,5,0,0:9,0 0,33,255:11:0:0:4,7,0,0:11,0 +17 335 . A <*> 0 . DP=32;DPR=30,0;I16=12,18,0,0,1077,40287,0,0,1529,83697,0,0,552,11934,0,0;QS=3,0;MQSB=0.264959;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,250:10:0:0:4,6,0,0:10,0 0,27,219:9:0:0:4,5,0,0:9,0 0,33,251:11:0:0:4,7,0,0:11,0 +17 336 . A <*> 0 . DP=32;DPR=31,0;I16=14,17,0,0,1088,39758,0,0,1612,89528,0,0,536,11574,0,0;QS=3,0;MQSB=0.274662;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:5,6,0,0:11,0 0,24,211:8:0:0:4,4,0,0:8,0 0,36,255:12:0:0:5,7,0,0:12,0 +17 337 . C <*> 0 . DP=32;DPR=30,0;I16=13,17,0,0,1115,42381,0,0,1552,85928,0,0,531,11565,0,0;QS=3,0;MQSB=0.301511;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,255:10:0:0:4,6,0,0:10,0 0,24,202:8:0:0:4,4,0,0:8,0 0,36,255:12:0:0:5,7,0,0:12,0 +17 338 . T <*> 0 . DP=30;DPR=30,0;I16=14,16,0,0,1191,47979,0,0,1560,86456,0,0,554,11878,0,0;QS=3,0;MQSB=0.242376;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,255:10:0:0:5,5,0,0:10,0 0,24,226:8:0:0:4,4,0,0:8,0 0,36,255:12:0:0:5,7,0,0:12,0 +17 339 . C <*> 0 . DP=31;DPR=31,0;I16=14,17,0,0,1130,43210,0,0,1589,87297,0,0,554,11874,0,0;QS=3,0;MQSB=0.175471;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:5,6,0,0:11,0 0,24,185:8:0:0:4,4,0,0:8,0 0,36,255:12:0:0:5,7,0,0:12,0 +17 340 . C <*> 0 . DP=31;DPR=31,0;I16=14,17,0,0,1196,47044,0,0,1589,87297,0,0,554,11852,0,0;QS=3,0;MQSB=0.175471;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:5,6,0,0:11,0 0,24,221:8:0:0:4,4,0,0:8,0 0,36,255:12:0:0:5,7,0,0:12,0 +17 341 . T <*> 0 . DP=31;DPR=31,0;I16=14,17,0,0,1227,48995,0,0,1589,87297,0,0,554,11862,0,0;QS=3,0;MQSB=0.175471;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:5,6,0,0:11,0 0,24,216:8:0:0:4,4,0,0:8,0 0,36,255:12:0:0:5,7,0,0:12,0 +17 342 . T <*> 0 . DP=31;DPR=31,0;I16=14,17,0,0,1162,43942,0,0,1589,87297,0,0,554,11904,0,0;QS=3,0;MQSB=0.175471;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:5,6,0,0:11,0 0,24,210:8:0:0:4,4,0,0:8,0 0,36,255:12:0:0:5,7,0,0:12,0 +17 343 . G <*> 0 . DP=32;DPR=31,0;I16=14,17,0,0,1150,43702,0,0,1620,90056,0,0,550,11962,0,0;QS=3,0;MQSB=0.283511;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,249:10:0:0:5,5,0,0:10,0 0,27,218:9:0:0:4,5,0,0:9,0 0,36,255:12:0:0:5,7,0,0:12,0 +17 344 . C <*> 0 . DP=32;DPR=32,0;I16=14,18,0,0,1181,45169,0,0,1649,90897,0,0,554,12036,0,0;QS=3,0;MQSB=0.210122;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:5,6,0,0:11,0 0,27,217:9:0:0:4,5,0,0:9,0 0,36,255:12:0:0:5,7,0,0:12,0 +17 345 . T <*> 0 . DP=31;DPR=31,0;I16=14,17,0,0,1205,47259,0,0,1589,87297,0,0,555,12129,0,0;QS=3,0;MQSB=0.175471;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:5,6,0,0:11,0 0,24,221:8:0:0:4,4,0,0:8,0 0,36,255:12:0:0:5,7,0,0:12,0 +17 346 . G <*> 0 . DP=31;DPR=31,0;I16=15,16,0,0,1147,43597,0,0,1620,90056,0,0,557,12255,0,0;QS=3,0;MQSB=0.220358;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:6,5,0,0:11,0 0,24,212:8:0:0:4,4,0,0:8,0 0,36,255:12:0:0:5,7,0,0:12,0 +17 347 . G <*> 0 . DP=31;DPR=30,0;I16=14,16,0,0,1119,42227,0,0,1560,86456,0,0,545,12189,0,0;QS=3,0;MQSB=0.242376;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,251:10:0:0:5,5,0,0:10,0 0,24,207:8:0:0:4,4,0,0:8,0 0,36,255:12:0:0:5,7,0,0:12,0 +17 348 . T <*> 0 . DP=32;DPR=31,0;I16=15,16,0,0,1145,43007,0,0,1620,90056,0,0,546,12300,0,0;QS=3,0;MQSB=0.220358;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,243:10:0:0:5,5,0,0:10,0 0,27,228:9:0:0:5,4,0,0:9,0 0,36,255:12:0:0:5,7,0,0:12,0 +17 349 . T <*> 0 . DP=32;DPR=32,0;I16=16,16,0,0,1194,45350,0,0,1680,93656,0,0,565,12731,0,0;QS=3,0;MQSB=0.201402;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,246:11:0:0:6,5,0,0:11,0 0,27,230:9:0:0:5,4,0,0:9,0 0,36,255:12:0:0:5,7,0,0:12,0 +17 350 . T <*> 0 . DP=31;DPR=31,0;I16=16,15,0,0,1142,43072,0,0,1651,92815,0,0,567,12837,0,0;QS=3,0;MQSB=0.286505;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,249:11:0:0:6,5,0,0:11,0 0,27,230:9:0:0:5,4,0,0:9,0 0,33,255:11:0:0:5,6,0,0:11,0 +17 351 . G <*> 0 . DP=31;DPR=31,0;I16=16,15,0,0,1146,43750,0,0,1651,92815,0,0,568,12920,0,0;QS=3,0;MQSB=0.286505;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:6,5,0,0:11,0 0,27,212:9:0:0:5,4,0,0:9,0 0,33,255:11:0:0:5,6,0,0:11,0 +17 352 . A <*> 0 . DP=31;DPR=30,0;I16=16,14,0,0,1150,45520,0,0,1591,89215,0,0,544,12404,0,0;QS=3,0;MQSB=0.242376;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:6,5,0,0:11,0 0,24,224:8:0:0:5,3,0,0:8,0 0,33,255:11:0:0:5,6,0,0:11,0 +17 353 . G <*> 0 . DP=29;DPR=29,0;I16=15,14,0,0,1109,43095,0,0,1562,88374,0,0,570,13064,0,0;QS=3,0;MQSB=0.424373;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,255:10:0:0:5,5,0,0:10,0 0,27,231:9:0:0:5,4,0,0:9,0 0,30,255:10:0:0:5,5,0,0:10,0 +17 354 . A <*> 0 . DP=28;DPR=28,0;I16=14,14,0,0,1078,42938,0,0,1502,84774,0,0,571,13075,0,0;QS=3,0;MQSB=0.450096;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,27,225:9:0:0:4,5,0,0:9,0 0,27,244:9:0:0:5,4,0,0:9,0 0,30,255:10:0:0:5,5,0,0:10,0 +17 355 . G T,<*> 0 . DP=28;DPR=27,1,0;I16=14,13,0,1,1001,37907,41,1681,1442,81174,60,3600,547,12487,25,625;QS=2.875,0.125,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.450096;BQB=1;MQ0F=0 PL:DP:DV:SP:DP4:DPR 14,0,200,38,203,231:9:1:0:4,4,0,1:8,1,0 0,27,222,27,222,222:9:0:0:5,4,0,0:9,0,0 0,30,255,30,255,255:10:0:0:5,5,0,0:10,0,0 +17 356 . G <*> 0 . DP=27;DPR=27,0;I16=14,13,0,0,993,37481,0,0,1465,83405,0,0,574,13174,0,0;QS=3,0;MQSB=0.580277;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,27,228:9:0:0:4,5,0,0:9,0 0,24,201:8:0:0:5,3,0,0:8,0 0,30,255:10:0:0:5,5,0,0:10,0 +17 357 . C <*> 0 . DP=28;DPR=27,0;I16=14,13,0,0,1021,39471,0,0,1465,83405,0,0,550,12584,0,0;QS=3,0;MQSB=0.580277;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,255:10:0:0:5,5,0,0:10,0 0,24,205:8:0:0:5,3,0,0:8,0 0,27,251:9:0:0:4,5,0,0:9,0 +17 358 . A <*> 0 . DP=28;DPR=28,0;I16=15,13,0,0,1050,40518,0,0,1525,87005,0,0,576,13216,0,0;QS=3,0;MQSB=0.556581;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,254:10:0:0:5,5,0,0:10,0 0,24,197:8:0:0:5,3,0,0:8,0 0,30,255:10:0:0:5,5,0,0:10,0 +17 359 . G <*> 0 . DP=29;DPR=28,0;I16=15,13,0,0,1085,42761,0,0,1525,87005,0,0,552,12620,0,0;QS=3,0;MQSB=0.556581;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,255:10:0:0:5,5,0,0:10,0 0,21,187:7:0:0:5,2,0,0:7,0 0,33,255:11:0:0:5,6,0,0:11,0 +17 360 . A <*> 0 . DP=29;DPR=29,0;I16=15,14,0,0,1111,43259,0,0,1585,90605,0,0,579,13297,0,0;QS=3,0;MQSB=0.604224;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,252:10:0:0:5,5,0,0:10,0 0,24,220:8:0:0:5,3,0,0:8,0 0,33,255:11:0:0:5,6,0,0:11,0 +17 361 . A <*> 0 . DP=29;DPR=29,0;I16=15,14,0,0,1116,43442,0,0,1585,90605,0,0,579,13273,0,0;QS=3,0;MQSB=0.604224;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,252:10:0:0:5,5,0,0:10,0 0,24,219:8:0:0:5,3,0,0:8,0 0,33,255:11:0:0:5,6,0,0:11,0 +17 362 . A <*> 0 . DP=29;DPR=29,0;I16=16,13,0,0,1104,42700,0,0,1585,90605,0,0,580,13272,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:6,5,0,0:11,0 0,24,218:8:0:0:5,3,0,0:8,0 0,30,255:10:0:0:5,5,0,0:10,0 +17 363 . A <*> 0 . DP=29;DPR=29,0;I16=16,13,0,0,1087,41437,0,0,1585,90605,0,0,581,13245,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:6,5,0,0:11,0 0,24,213:8:0:0:5,3,0,0:8,0 0,30,255:10:0:0:5,5,0,0:10,0 +17 364 . T <*> 0 . DP=29;DPR=29,0;I16=16,13,0,0,1032,37960,0,0,1585,90605,0,0,582,13244,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,250:11:0:0:6,5,0,0:11,0 0,24,205:8:0:0:5,3,0,0:8,0 0,30,255:10:0:0:5,5,0,0:10,0 +17 365 . G <*> 0 . DP=29;DPR=29,0;I16=16,13,0,0,1105,43079,0,0,1585,90605,0,0,582,13218,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:6,5,0,0:11,0 0,24,211:8:0:0:5,3,0,0:8,0 0,30,255:10:0:0:5,5,0,0:10,0 +17 366 . A <*> 0 . DP=29;DPR=29,0;I16=16,13,0,0,1090,41562,0,0,1585,90605,0,0,581,13167,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:6,5,0,0:11,0 0,24,211:8:0:0:5,3,0,0:8,0 0,30,255:10:0:0:5,5,0,0:10,0 +17 367 . T <*> 0 . DP=29;DPR=29,0;I16=16,13,0,0,1055,39149,0,0,1585,90605,0,0,579,13093,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:6,5,0,0:11,0 0,24,204:8:0:0:5,3,0,0:8,0 0,30,255:10:0:0:5,5,0,0:10,0 +17 368 . A <*> 0 . DP=29;DPR=29,0;I16=16,13,0,0,1054,39632,0,0,1585,90605,0,0,576,12998,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:6,5,0,0:11,0 0,24,208:8:0:0:5,3,0,0:8,0 0,30,255:10:0:0:5,5,0,0:10,0 +17 369 . T <*> 0 . DP=28;DPR=27,0;I16=16,11,0,0,1037,40275,0,0,1496,86164,0,0,548,12256,0,0;QS=3,0;MQSB=0.659218;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,250:10:0:0:6,4,0,0:10,0 0,21,196:7:0:0:5,2,0,0:7,0 0,30,255:10:0:0:5,5,0,0:10,0 +17 370 . C <*> 0 . DP=28;DPR=28,0;I16=16,12,0,0,1045,40219,0,0,1556,89764,0,0,570,12790,0,0;QS=3,0;MQSB=0.705296;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,255:10:0:0:6,4,0,0:10,0 0,24,201:8:0:0:5,3,0,0:8,0 0,30,255:10:0:0:5,5,0,0:10,0 +17 371 . T <*> 0 . DP=29;DPR=29,0;I16=16,13,0,0,1155,46591,0,0,1616,93364,0,0,567,12725,0,0;QS=3,0;MQSB=0.744925;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,255:10:0:0:6,4,0,0:10,0 0,24,227:8:0:0:5,3,0,0:8,0 0,33,255:11:0:0:5,6,0,0:11,0 +17 372 . C <*> 0 . DP=30;DPR=30,0;I16=16,14,0,0,1139,44019,0,0,1676,96964,0,0,564,12636,0,0;QS=3,0;MQSB=0.779025;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:6,5,0,0:11,0 0,24,215:8:0:0:5,3,0,0:8,0 0,33,255:11:0:0:5,6,0,0:11,0 +17 373 . A <*> 0 . DP=30;DPR=30,0;I16=16,14,0,0,1142,44118,0,0,1676,96964,0,0,561,12525,0,0;QS=3,0;MQSB=0.779025;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:6,5,0,0:11,0 0,24,220:8:0:0:5,3,0,0:8,0 0,33,255:11:0:0:5,6,0,0:11,0 +17 374 . T <*> 0 . DP=30;DPR=30,0;I16=16,14,0,0,1098,41180,0,0,1676,96964,0,0,556,12344,0,0;QS=3,0;MQSB=0.779025;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:6,5,0,0:11,0 0,24,221:8:0:0:5,3,0,0:8,0 0,33,255:11:0:0:5,6,0,0:11,0 +17 375 . A T,<*> 0 . DP=31;DPR=30,1,0;I16=17,13,0,1,1138,43798,14,196,1676,96964,60,3600,547,12177,4,16;QS=2.9661,0.0338983,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.763662;BQB=1;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,36,255,36,255,255:12:0:0:7,5,0,0:12,0,0 0,24,218,24,218,218:8:0:0:5,3,0,0:8,0,0 0,18,255,30,255,255:11:1:0:5,5,0,1:10,1,0 +17 376 . G <*> 0 . DP=31;DPR=31,0;I16=17,14,0,0,1131,42581,0,0,1736,100564,0,0,547,12073,0,0;QS=3,0;MQSB=0.763662;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,36,255:12:0:0:7,5,0,0:12,0 0,24,220:8:0:0:5,3,0,0:8,0 0,33,255:11:0:0:5,6,0,0:11,0 +17 377 . T <*> 0 . DP=31;DPR=30,0;I16=16,14,0,0,1105,41629,0,0,1676,96964,0,0,518,11360,0,0;QS=3,0;MQSB=0.779025;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:6,5,0,0:11,0 0,24,211:8:0:0:5,3,0,0:8,0 0,33,255:11:0:0:5,6,0,0:11,0 +17 378 . T <*> 0 . DP=30;DPR=30,0;I16=18,12,0,0,1098,41066,0,0,1707,99723,0,0,541,11927,0,0;QS=3,0;MQSB=0.878946;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,39,255:13:0:0:8,5,0,0:13,0 0,21,186:7:0:0:5,2,0,0:7,0 0,30,255:10:0:0:5,5,0,0:10,0 +17 379 . G <*> 0 . DP=29;DPR=28,0;I16=18,10,0,0,1053,40181,0,0,1618,95282,0,0,534,11848,0,0;QS=3,0;MQSB=0.981777;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:8,3,0,0:11,0 0,21,187:7:0:0:5,2,0,0:7,0 0,30,255:10:0:0:5,5,0,0:10,0 +17 380 . C <*> 0 . DP=29;DPR=28,0;I16=18,10,0,0,1087,42743,0,0,1618,95282,0,0,514,11172,0,0;QS=3,0;MQSB=0.981777;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,36,255:12:0:0:8,4,0,0:12,0 0,18,177:6:0:0:5,1,0,0:6,0 0,30,255:10:0:0:5,5,0,0:10,0 +17 381 . T <*> 0 . DP=29;DPR=29,0;I16=18,11,0,0,1168,47412,0,0,1678,98882,0,0,537,11729,0,0;QS=3,0;MQSB=0.987702;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,36,255:12:0:0:8,4,0,0:12,0 0,21,212:7:0:0:5,2,0,0:7,0 0,30,255:10:0:0:5,5,0,0:10,0 +17 382 . T <*> 0 . DP=29;DPR=28,0;I16=17,11,0,0,1054,40450,0,0,1618,95282,0,0,510,11068,0,0;QS=3,0;MQSB=0.990092;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,33,255:11:0:0:7,4,0,0:11,0 0,21,182:7:0:0:5,2,0,0:7,0 0,30,255:10:0:0:5,5,0,0:10,0 +17 383 . T <*> 0 . DP=29;DPR=28,0;I16=18,10,0,0,1052,39798,0,0,1618,95282,0,0,507,11013,0,0;QS=3,0;MQSB=0.981777;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,36,255:12:0:0:8,4,0,0:12,0 0,18,165:6:0:0:5,1,0,0:6,0 0,30,255:10:0:0:5,5,0,0:10,0 +17 384 . A <*> 0 . DP=31;DPR=30,0;I16=19,11,0,0,1077,39885,0,0,1738,102482,0,0,504,10988,0,0;QS=3,0;MQSB=0.985292;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,39,255:13:0:0:8,5,0,0:13,0 0,21,176:7:0:0:6,1,0,0:7,0 0,30,255:10:0:0:5,5,0,0:10,0 +17 385 . C <*> 0 . DP=31;DPR=31,0;I16=19,12,0,0,1118,41180,0,0,1798,106082,0,0,527,11569,0,0;QS=3,0;MQSB=0.989977;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,39,255:13:0:0:8,5,0,0:13,0 0,24,186:8:0:0:6,2,0,0:8,0 0,30,255:10:0:0:5,5,0,0:10,0 +17 386 . T <*> 0 . DP=30;DPR=30,0;I16=18,12,0,0,1158,45592,0,0,1738,102482,0,0,526,11556,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,39,255:13:0:0:8,5,0,0:13,0 0,21,191:7:0:0:5,2,0,0:7,0 0,30,255:10:0:0:5,5,0,0:10,0 +17 387 . T <*> 0 . DP=30;DPR=30,0;I16=18,12,0,0,1105,41821,0,0,1738,102482,0,0,525,11573,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,39,255:13:0:0:8,5,0,0:13,0 0,21,187:7:0:0:5,2,0,0:7,0 0,30,255:10:0:0:5,5,0,0:10,0 +17 388 . T <*> 0 . DP=29;DPR=29,0;I16=17,12,0,0,1089,41577,0,0,1678,98882,0,0,523,11519,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,39,255:13:0:0:8,5,0,0:13,0 0,18,180:6:0:0:4,2,0,0:6,0 0,30,255:10:0:0:5,5,0,0:10,0 +17 389 . G <*> 0 . DP=29;DPR=29,0;I16=17,12,0,0,1067,40095,0,0,1678,98882,0,0,520,11444,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,39,255:13:0:0:8,5,0,0:13,0 0,18,171:6:0:0:4,2,0,0:6,0 0,30,255:10:0:0:5,5,0,0:10,0 +17 390 . C <*> 0 . DP=29;DPR=29,0;I16=17,12,0,0,1071,40423,0,0,1678,98882,0,0,517,11399,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,39,255:13:0:0:8,5,0,0:13,0 0,18,162:6:0:0:4,2,0,0:6,0 0,30,255:10:0:0:5,5,0,0:10,0 +17 391 . A <*> 0 . DP=29;DPR=29,0;I16=18,11,0,0,1091,41603,0,0,1647,96123,0,0,515,11383,0,0;QS=3,0;MQSB=0.995968;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,39,255:13:0:0:8,5,0,0:13,0 0,18,163:6:0:0:4,2,0,0:6,0 0,30,255:10:0:0:6,4,0,0:10,0 +17 392 . T <*> 0 . DP=29;DPR=29,0;I16=18,11,0,0,1046,38838,0,0,1647,96123,0,0,515,11395,0,0;QS=3,0;MQSB=0.995968;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,39,255:13:0:0:8,5,0,0:13,0 0,15,153:5:0:0:3,2,0,0:5,0 0,33,255:11:0:0:7,4,0,0:11,0 +17 393 . A <*> 0 . DP=28;DPR=28,0;I16=17,11,0,0,1014,37582,0,0,1587,92523,0,0,517,11435,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,36,255:12:0:0:7,5,0,0:12,0 0,15,133:5:0:0:3,2,0,0:5,0 0,33,255:11:0:0:7,4,0,0:11,0 +17 394 . T <*> 0 . DP=28;DPR=28,0;I16=17,11,0,0,1022,38342,0,0,1587,92523,0,0,519,11503,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,36,255:12:0:0:7,5,0,0:12,0 0,15,141:5:0:0:3,2,0,0:5,0 0,33,255:11:0:0:7,4,0,0:11,0 +17 395 . T <*> 0 . DP=28;DPR=28,0;I16=17,11,0,0,1060,40596,0,0,1587,92523,0,0,521,11599,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,36,255:12:0:0:7,5,0,0:12,0 0,15,164:5:0:0:3,2,0,0:5,0 0,33,255:11:0:0:7,4,0,0:11,0 +17 396 . T <*> 0 . DP=28;DPR=28,0;I16=17,11,0,0,1032,39228,0,0,1587,92523,0,0,523,11723,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,36,255:12:0:0:7,5,0,0:12,0 0,15,158:5:0:0:3,2,0,0:5,0 0,33,255:11:0:0:7,4,0,0:11,0 +17 397 . T <*> 0 . DP=28;DPR=28,0;I16=17,11,0,0,1046,39510,0,0,1587,92523,0,0,524,11824,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,36,255:12:0:0:7,5,0,0:12,0 0,15,149:5:0:0:3,2,0,0:5,0 0,33,255:11:0:0:7,4,0,0:11,0 +17 398 . A <*> 0 . DP=28;DPR=28,0;I16=17,11,0,0,1021,38105,0,0,1587,92523,0,0,524,11850,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,39,255:13:0:0:8,5,0,0:13,0 0,15,144:5:0:0:3,2,0,0:5,0 0,30,255:10:0:0:6,4,0,0:10,0 +17 399 . A <*> 0 . DP=28;DPR=28,0;I16=17,11,0,0,1015,38469,0,0,1587,92523,0,0,526,11900,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,39,255:13:0:0:8,5,0,0:13,0 0,15,140:5:0:0:3,2,0,0:5,0 0,30,255:10:0:0:6,4,0,0:10,0 +17 400 . A <*> 0 . DP=29;DPR=29,0;I16=17,12,0,0,1056,39702,0,0,1647,96123,0,0,526,11828,0,0;QS=3,0;MQSB=0.988062;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,39,255:13:0:0:8,5,0,0:13,0 0,15,159:5:0:0:3,2,0,0:5,0 0,33,255:11:0:0:6,5,0,0:11,0 +17 401 . A <*> 0 . DP=29;DPR=28,0;I16=17,11,0,0,1052,40302,0,0,1587,92523,0,0,501,11113,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,39,255:13:0:0:8,5,0,0:13,0 0,15,160:5:0:0:3,2,0,0:5,0 0,30,255:10:0:0:6,4,0,0:10,0 +17 402 . T <*> 0 . DP=29;DPR=29,0;I16=17,12,0,0,1082,41232,0,0,1647,96123,0,0,526,11680,0,0;QS=3,0;MQSB=0.988062;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,39,255:13:0:0:8,5,0,0:13,0 0,15,149:5:0:0:3,2,0,0:5,0 0,33,255:11:0:0:6,5,0,0:11,0 +17 403 . T <*> 0 . DP=29;DPR=29,0;I16=17,12,0,0,1085,40985,0,0,1647,96123,0,0,526,11654,0,0;QS=3,0;MQSB=0.988062;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,39,255:13:0:0:8,5,0,0:13,0 0,15,148:5:0:0:3,2,0,0:5,0 0,33,255:11:0:0:6,5,0,0:11,0 +17 404 . G <*> 0 . DP=29;DPR=29,0;I16=17,12,0,0,1074,40524,0,0,1647,96123,0,0,525,11609,0,0;QS=3,0;MQSB=0.988062;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,39,255:13:0:0:8,5,0,0:13,0 0,15,131:5:0:0:3,2,0,0:5,0 0,33,255:11:0:0:6,5,0,0:11,0 +17 405 . T <*> 0 . DP=27;DPR=26,0;I16=16,10,0,0,988,37870,0,0,1498,88082,0,0,519,11543,0,0;QS=3,0;MQSB=0.987578;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,39,255:13:0:0:8,5,0,0:13,0 0,9,103:3:0:0:2,1,0,0:3,0 0,30,255:10:0:0:6,4,0,0:10,0 +17 406 . G <*> 0 . DP=27;DPR=27,0;I16=16,11,0,0,976,36752,0,0,1558,91682,0,0,527,11601,0,0;QS=3,0;MQSB=0.992419;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,39,255:13:0:0:8,5,0,0:13,0 0,12,125:4:0:0:2,2,0,0:4,0 0,30,247:10:0:0:6,4,0,0:10,0 +17 407 . A <*> 0 . DP=27;DPR=27,0;I16=16,11,0,0,1007,38355,0,0,1558,91682,0,0,526,11538,0,0;QS=3,0;MQSB=0.992419;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,39,255:13:0:0:8,5,0,0:13,0 0,12,125:4:0:0:2,2,0,0:4,0 0,30,255:10:0:0:6,4,0,0:10,0 +17 408 . C <*> 0 . DP=28;DPR=27,0;I16=16,11,0,0,1006,38136,0,0,1558,91682,0,0,521,11489,0,0;QS=3,0;MQSB=0.992419;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,42,255:14:0:0:8,6,0,0:14,0 0,9,110:3:0:0:2,1,0,0:3,0 0,30,244:10:0:0:6,4,0,0:10,0 +17 409 . T <*> 0 . DP=29;DPR=29,0;I16=17,12,0,0,1100,42734,0,0,1678,98882,0,0,525,11503,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,42,255:14:0:0:8,6,0,0:14,0 0,12,131:4:0:0:2,2,0,0:4,0 0,33,255:11:0:0:7,4,0,0:11,0 +17 410 . T <*> 0 . DP=29;DPR=29,0;I16=17,12,0,0,1035,38325,0,0,1678,98882,0,0,524,11432,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,42,255:14:0:0:8,6,0,0:14,0 0,12,125:4:0:0:2,2,0,0:4,0 0,33,255:11:0:0:7,4,0,0:11,0 +17 411 . T <*> 0 . DP=29;DPR=27,0;I16=17,10,0,0,1003,37747,0,0,1558,91682,0,0,496,10716,0,0;QS=3,0;MQSB=0.984677;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,42,255:14:0:0:8,6,0,0:14,0 0,9,104:3:0:0:2,1,0,0:3,0 0,30,255:10:0:0:7,3,0,0:10,0 +17 412 . C T,<*> 0 . DP=30;DPR=29,1,0;I16=17,12,1,0,1094,42458,14,196,1678,98882,60,3600,495,10659,25,625;QS=2.97455,0.0254545,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.991968;BQB=1;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,30,255,42,255,255:15:1:0:8,6,1,0:14,1,0 0,12,124,12,124,124:4:0:0:2,2,0,0:4,0,0 0,33,255,33,255,255:11:0:0:7,4,0,0:11,0,0 +17 413 . A <*> 0 . DP=31;DPR=31,0;I16=18,13,0,0,1189,45985,0,0,1798,106082,0,0,520,11258,0,0;QS=3,0;MQSB=0.995005;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:9,8,0,0:17,0 0,9,102:3:0:0:2,1,0,0:3,0 0,33,255:11:0:0:7,4,0,0:11,0 +17 414 . T <*> 0 . DP=30;DPR=30,0;I16=18,12,0,0,1151,44355,0,0,1738,102482,0,0,523,11265,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255:16:0:0:9,7,0,0:16,0 0,9,109:3:0:0:2,1,0,0:3,0 0,33,255:11:0:0:7,4,0,0:11,0 +17 415 . G <*> 0 . DP=30;DPR=30,0;I16=18,12,0,0,1131,43175,0,0,1738,102482,0,0,526,11306,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255:16:0:0:9,7,0,0:16,0 0,9,110:3:0:0:2,1,0,0:3,0 0,33,255:11:0:0:7,4,0,0:11,0 +17 416 . G <*> 0 . DP=30;DPR=29,0;I16=17,12,0,0,1083,41273,0,0,1678,98882,0,0,514,11156,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255:16:0:0:9,7,0,0:16,0 0,9,114:3:0:0:2,1,0,0:3,0 0,30,253:10:0:0:6,4,0,0:10,0 +17 417 . C <*> 0 . DP=30;DPR=30,0;I16=18,12,0,0,1114,42244,0,0,1738,102482,0,0,531,11439,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255:16:0:0:9,7,0,0:16,0 0,9,108:3:0:0:2,1,0,0:3,0 0,33,255:11:0:0:7,4,0,0:11,0 +17 418 . A <*> 0 . DP=30;DPR=30,0;I16=18,12,0,0,1146,44248,0,0,1738,102482,0,0,532,11478,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255:16:0:0:9,7,0,0:16,0 0,9,111:3:0:0:2,1,0,0:3,0 0,33,255:11:0:0:7,4,0,0:11,0 +17 419 . T <*> 0 . DP=30;DPR=30,0;I16=18,12,0,0,1117,42327,0,0,1738,102482,0,0,532,11498,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255:16:0:0:9,7,0,0:16,0 0,9,112:3:0:0:2,1,0,0:3,0 0,33,255:11:0:0:7,4,0,0:11,0 +17 420 . A <*> 0 . DP=31;DPR=31,0;I16=18,13,0,0,1117,41011,0,0,1798,106082,0,0,532,11550,0,0;QS=3,0;MQSB=0.995005;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255:16:0:0:9,7,0,0:16,0 0,9,108:3:0:0:2,1,0,0:3,0 0,36,255:12:0:0:7,5,0,0:12,0 +17 421 . A <*> 0 . DP=33;DPR=33,0;I16=19,14,0,0,1208,45398,0,0,1887,110523,0,0,533,11635,0,0;QS=3,0;MQSB=0.986656;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255:16:0:0:9,7,0,0:16,0 0,9,113:3:0:0:2,1,0,0:3,0 0,42,255:14:0:0:8,6,0,0:14,0 +17 422 . A <*> 0 . DP=33;DPR=32,0;I16=19,13,0,0,1205,46441,0,0,1827,106923,0,0,510,11082,0,0;QS=3,0;MQSB=0.991023;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255:16:0:0:9,7,0,0:16,0 0,9,116:3:0:0:2,1,0,0:3,0 0,39,255:13:0:0:8,5,0,0:13,0 +17 423 . T <*> 0 . DP=32;DPR=32,0;I16=19,13,0,0,1202,45416,0,0,1827,106923,0,0,538,11818,0,0;QS=3,0;MQSB=0.991023;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255:16:0:0:9,7,0,0:16,0 0,9,110:3:0:0:2,1,0,0:3,0 0,39,255:13:0:0:8,5,0,0:13,0 +17 424 . A <*> 0 . DP=32;DPR=32,0;I16=19,13,0,0,1147,41685,0,0,1827,106923,0,0,539,11867,0,0;QS=3,0;MQSB=0.991023;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255:16:0:0:9,7,0,0:16,0 0,9,106:3:0:0:2,1,0,0:3,0 0,39,255:13:0:0:8,5,0,0:13,0 +17 425 . A <*> 0 . DP=29;DPR=29,0;I16=16,13,0,0,1070,40616,0,0,1647,96123,0,0,542,11900,0,0;QS=3,0;MQSB=0.976248;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,45,255:15:0:0:8,7,0,0:15,0 0,9,111:3:0:0:2,1,0,0:3,0 0,33,249:11:0:0:6,5,0,0:11,0 +17 426 . T <*> 0 . DP=29;DPR=28,0;I16=16,12,0,0,997,36561,0,0,1587,92523,0,0,519,11287,0,0;QS=3,0;MQSB=0.982906;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,45,255:15:0:0:8,7,0,0:15,0 0,9,105:3:0:0:2,1,0,0:3,0 0,30,225:10:0:0:6,4,0,0:10,0 +17 427 . A <*> 0 . DP=29;DPR=29,0;I16=16,13,0,0,1024,37266,0,0,1647,96123,0,0,546,11952,0,0;QS=3,0;MQSB=0.976248;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,45,255:15:0:0:8,7,0,0:15,0 0,9,111:3:0:0:2,1,0,0:3,0 0,33,242:11:0:0:6,5,0,0:11,0 +17 428 . C <*> 0 . DP=29;DPR=29,0;I16=16,13,0,0,1064,39706,0,0,1647,96123,0,0,548,12020,0,0;QS=3,0;MQSB=0.976248;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,45,255:15:0:0:8,7,0,0:15,0 0,9,111:3:0:0:2,1,0,0:3,0 0,33,254:11:0:0:6,5,0,0:11,0 +17 429 . T <*> 0 . DP=30;DPR=30,0;I16=16,14,0,0,1150,44918,0,0,1707,99723,0,0,549,12067,0,0;QS=3,0;MQSB=0.969373;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255:16:0:0:8,8,0,0:16,0 0,9,115:3:0:0:2,1,0,0:3,0 0,33,255:11:0:0:6,5,0,0:11,0 +17 430 . G <*> 0 . DP=30;DPR=30,0;I16=16,14,0,0,1113,42443,0,0,1707,99723,0,0,551,12145,0,0;QS=3,0;MQSB=0.969373;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255:16:0:0:8,8,0,0:16,0 0,9,112:3:0:0:2,1,0,0:3,0 0,33,246:11:0:0:6,5,0,0:11,0 +17 431 . G <*> 0 . DP=30;DPR=28,0;I16=14,14,0,0,1003,36953,0,0,1587,92523,0,0,553,12255,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,45,255:15:0:0:7,8,0,0:15,0 0,9,101:3:0:0:2,1,0,0:3,0 0,30,225:10:0:0:5,5,0,0:10,0 +17 432 . T <*> 0 . DP=28;DPR=28,0;I16=14,14,0,0,1049,39621,0,0,1587,92523,0,0,556,12346,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,45,255:15:0:0:7,8,0,0:15,0 0,9,114:3:0:0:2,1,0,0:3,0 0,30,255:10:0:0:5,5,0,0:10,0 +17 433 . T <*> 0 . DP=28;DPR=26,0;I16=14,12,0,0,949,35443,0,0,1467,85323,0,0,509,11217,0,0;QS=3,0;MQSB=0.967472;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,42,255:14:0:0:7,7,0,0:14,0 0,9,112:3:0:0:2,1,0,0:3,0 0,27,227:9:0:0:5,4,0,0:9,0 +17 434 . T <*> 0 . DP=29;DPR=29,0;I16=15,14,0,0,1036,37654,0,0,1647,96123,0,0,561,12567,0,0;QS=3,0;MQSB=0.960561;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255:16:0:0:8,8,0,0:16,0 0,9,98:3:0:0:2,1,0,0:3,0 0,30,243:10:0:0:5,5,0,0:10,0 +17 435 . A <*> 0 . DP=29;DPR=28,0;I16=15,13,0,0,1024,37970,0,0,1587,92523,0,0,556,12560,0,0;QS=3,0;MQSB=0.968414;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,45,255:15:0:0:8,7,0,0:15,0 0,9,103:3:0:0:2,1,0,0:3,0 0,30,237:10:0:0:5,5,0,0:10,0 +17 436 . T <*> 0 . DP=28;DPR=28,0;I16=14,14,0,0,998,36220,0,0,1587,92523,0,0,564,12654,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255:16:0:0:8,8,0,0:16,0 0,9,110:3:0:0:2,1,0,0:3,0 0,27,223:9:0:0:4,5,0,0:9,0 +17 437 . T <*> 0 . DP=28;DPR=27,0;I16=13,14,0,0,990,36832,0,0,1558,91682,0,0,549,12435,0,0;QS=3,0;MQSB=0.999706;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255:16:0:0:8,8,0,0:16,0 0,9,109:3:0:0:2,1,0,0:3,0 0,24,207:8:0:0:3,5,0,0:8,0 +17 438 . A <*> 0 . DP=28;DPR=27,0;I16=14,13,0,0,972,35640,0,0,1527,88923,0,0,540,12082,0,0;QS=3,0;MQSB=0.9585;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255:16:0:0:8,8,0,0:16,0 0,9,107:3:0:0:2,1,0,0:3,0 0,24,216:8:0:0:4,4,0,0:8,0 +17 439 . C <*> 0 . DP=28;DPR=28,0;I16=14,14,0,0,1055,40273,0,0,1587,92523,0,0,563,12649,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255:16:0:0:8,8,0,0:16,0 0,9,107:3:0:0:2,1,0,0:3,0 0,27,224:9:0:0:4,5,0,0:9,0 +17 440 . A <*> 0 . DP=28;DPR=28,0;I16=14,14,0,0,1095,43251,0,0,1587,92523,0,0,561,12615,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255:16:0:0:8,8,0,0:16,0 0,9,115:3:0:0:2,1,0,0:3,0 0,27,247:9:0:0:4,5,0,0:9,0 +17 441 . G <*> 0 . DP=29;DPR=29,0;I16=15,14,0,0,1068,40344,0,0,1647,96123,0,0,559,12605,0,0;QS=3,0;MQSB=0.960561;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:9,8,0,0:17,0 0,9,104:3:0:0:2,1,0,0:3,0 0,27,198:9:0:0:4,5,0,0:9,0 +17 442 . A <*> 0 . DP=29;DPR=29,0;I16=15,14,0,0,1091,41507,0,0,1647,96123,0,0,558,12620,0,0;QS=3,0;MQSB=0.960561;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:9,8,0,0:17,0 0,9,112:3:0:0:2,1,0,0:3,0 0,27,233:9:0:0:4,5,0,0:9,0 +17 443 . A <*> 0 . DP=30;DPR=29,0;I16=15,14,0,0,1173,49439,0,0,1647,96123,0,0,557,12661,0,0;QS=3,0;MQSB=0.960561;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:9,8,0,0:17,0 0,9,129:3:0:0:2,1,0,0:3,0 0,27,246:9:0:0:4,5,0,0:9,0 +17 444 . G <*> 0 . DP=29;DPR=28,0;I16=15,13,0,0,1095,44661,0,0,1587,92523,0,0,557,12727,0,0;QS=3,0;MQSB=0.968414;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:9,8,0,0:17,0 0,6,91:2:0:0:2,0,0,0:2,0 0,27,227:9:0:0:4,5,0,0:9,0 +17 445 . C <*> 0 . DP=30;DPR=29,0;I16=16,13,0,0,1100,43706,0,0,1647,96123,0,0,557,12817,0,0;QS=3,0;MQSB=0.976248;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:9,8,0,0:17,0 0,9,111:3:0:0:3,0,0,0:3,0 0,27,219:9:0:0:4,5,0,0:9,0 +17 446 . A <*> 0 . DP=30;DPR=29,0;I16=16,13,0,0,1107,44265,0,0,1647,96123,0,0,557,12881,0,0;QS=3,0;MQSB=0.976248;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:9,8,0,0:17,0 0,9,115:3:0:0:3,0,0,0:3,0 0,27,232:9:0:0:4,5,0,0:9,0 +17 447 . C <*> 0 . DP=29;DPR=28,0;I16=16,12,0,0,1108,45364,0,0,1618,95282,0,0,555,12817,0,0;QS=3,0;MQSB=0.856268;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255:16:0:0:9,7,0,0:16,0 0,9,114:3:0:0:3,0,0,0:3,0 0,27,235:9:0:0:4,5,0,0:9,0 +17 448 . T <*> 0 . DP=29;DPR=28,0;I16=16,12,0,0,1125,47237,0,0,1618,95282,0,0,553,12773,0,0;QS=3,0;MQSB=0.856268;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255:16:0:0:9,7,0,0:16,0 0,9,118:3:0:0:3,0,0,0:3,0 0,27,240:9:0:0:4,5,0,0:9,0 +17 449 . A <*> 0 . DP=28;DPR=27,0;I16=15,12,0,0,1091,45981,0,0,1558,91682,0,0,552,12748,0,0;QS=3,0;MQSB=0.84246;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255:16:0:0:9,7,0,0:16,0 0,6,90:2:0:0:2,0,0,0:2,0 0,27,245:9:0:0:4,5,0,0:9,0 +17 450 . G <*> 0 . DP=28;DPR=27,0;I16=15,12,0,0,1069,44603,0,0,1558,91682,0,0,551,12741,0,0;QS=3,0;MQSB=0.84246;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255:16:0:0:9,7,0,0:16,0 0,6,91:2:0:0:2,0,0,0:2,0 0,27,233:9:0:0:4,5,0,0:9,0 +17 451 . A <*> 0 . DP=28;DPR=27,0;I16=15,12,0,0,1021,41371,0,0,1558,91682,0,0,550,12752,0,0;QS=3,0;MQSB=0.84246;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255:16:0:0:9,7,0,0:16,0 0,6,93:2:0:0:2,0,0,0:2,0 0,27,244:9:0:0:4,5,0,0:9,0 +17 452 . A <*> 0 . DP=31;DPR=29,0;I16=18,11,0,0,1079,43353,0,0,1678,98882,0,0,530,12420,0,0;QS=3,0;MQSB=0.884952;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:11,7,0,0:18,0 0,9,110:3:0:0:3,0,0,0:3,0 0,24,225:8:0:0:4,4,0,0:8,0 +17 453 . A <*> 0 . DP=31;DPR=28,0;I16=17,11,0,0,1037,41069,0,0,1649,98041,0,0,508,11882,0,0;QS=3,0;MQSB=0.967085;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:11,7,0,0:18,0 0,9,111:3:0:0:3,0,0,0:3,0 0,21,221:7:0:0:3,4,0,0:7,0 +17 454 . A <*> 0 . DP=31;DPR=30,0;I16=18,12,0,0,1158,47028,0,0,1738,102482,0,0,554,12904,0,0;QS=3,0;MQSB=0.878946;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:10,7,0,0:17,0 0,9,113:3:0:0:3,0,0,0:3,0 0,30,255:10:0:0:5,5,0,0:10,0 +17 455 . T <*> 0 . DP=32;DPR=30,0;I16=17,13,0,0,1148,46574,0,0,1715,100251,0,0,550,12864,0,0;QS=3,0;MQSB=0.973855;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255:16:0:0:9,7,0,0:16,0 0,9,113:3:0:0:3,0,0,0:3,0 0,33,255:11:0:0:5,6,0,0:11,0 +17 456 . G <*> 0 . DP=32;DPR=30,0;I16=17,13,0,0,1161,47287,0,0,1746,103010,0,0,534,12296,0,0;QS=3,0;MQSB=0.998031;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:10,7,0,0:17,0 0,9,116:3:0:0:3,0,0,0:3,0 0,30,245:10:0:0:4,6,0,0:10,0 +17 457 . C <*> 0 . DP=33;DPR=32,0;I16=19,13,0,0,1218,48642,0,0,1835,107451,0,0,563,12967,0,0;QS=3,0;MQSB=0.985204;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:11,7,0,0:18,0 0,9,118:3:0:0:3,0,0,0:3,0 0,33,255:11:0:0:5,6,0,0:11,0 +17 458 . A <*> 0 . DP=33;DPR=32,0;I16=19,13,0,0,1226,49034,0,0,1835,107451,0,0,568,12990,0,0;QS=3,0;MQSB=0.985204;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:11,7,0,0:18,0 0,9,111:3:0:0:3,0,0,0:3,0 0,33,255:11:0:0:5,6,0,0:11,0 +17 459 . T <*> 0 . DP=33;DPR=31,0;I16=18,13,0,0,1167,46981,0,0,1775,103851,0,0,565,12945,0,0;QS=3,0;MQSB=0.980167;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:11,7,0,0:18,0 0,6,92:2:0:0:2,0,0,0:2,0 0,33,255:11:0:0:5,6,0,0:11,0 +17 460 . G <*> 0 . DP=32;DPR=31,0;I16=19,12,0,0,1219,50105,0,0,1775,103851,0,0,575,12929,0,0;QS=3,0;MQSB=0.989977;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:11,7,0,0:18,0 0,9,116:3:0:0:3,0,0,0:3,0 0,30,255:10:0:0:5,5,0,0:10,0 +17 461 . T <*> 0 . DP=32;DPR=31,0;I16=19,12,0,0,1213,49819,0,0,1775,103851,0,0,577,12845,0,0;QS=3,0;MQSB=0.989977;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:11,7,0,0:18,0 0,9,115:3:0:0:3,0,0,0:3,0 0,30,255:10:0:0:5,5,0,0:10,0 +17 462 . G <*> 0 . DP=32;DPR=31,0;I16=19,12,0,0,1190,48962,0,0,1775,103851,0,0,580,12792,0,0;QS=3,0;MQSB=0.989977;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:10,7,0,0:17,0 0,12,119:4:0:0:4,0,0,0:4,0 0,30,241:10:0:0:5,5,0,0:10,0 +17 463 . G <*> 0 . DP=32;DPR=31,0;I16=19,12,0,0,1114,44214,0,0,1775,103851,0,0,584,12770,0,0;QS=3,0;MQSB=0.989977;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:10,7,0,0:17,0 0,12,114:4:0:0:4,0,0,0:4,0 0,30,221:10:0:0:5,5,0,0:10,0 +17 464 . A <*> 0 . DP=32;DPR=29,0;I16=18,11,0,0,1100,43908,0,0,1686,99410,0,0,556,12106,0,0;QS=3,0;MQSB=0.99095;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:10,7,0,0:17,0 0,12,133:4:0:0:4,0,0,0:4,0 0,24,213:8:0:0:4,4,0,0:8,0 +17 465 . C <*> 0 . DP=33;DPR=31,0;I16=20,11,0,0,1191,48085,0,0,1775,103851,0,0,586,12786,0,0;QS=3,0;MQSB=0.996597;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:10,7,0,0:17,0 0,15,140:5:0:0:5,0,0,0:5,0 0,27,231:9:0:0:5,4,0,0:9,0 +17 466 . A <*> 0 . DP=34;DPR=33,0;I16=21,12,0,0,1293,53311,0,0,1895,111051,0,0,597,12897,0,0;QS=3,0;MQSB=0.995633;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:11,7,0,0:18,0 0,15,154:5:0:0:5,0,0,0:5,0 0,30,255:10:0:0:5,5,0,0:10,0 +17 467 . A <*> 0 . DP=34;DPR=32,0;I16=21,11,0,0,1256,51450,0,0,1835,107451,0,0,597,12891,0,0;QS=3,0;MQSB=0.998231;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:11,7,0,0:18,0 0,15,157:5:0:0:5,0,0,0:5,0 0,27,248:9:0:0:5,4,0,0:9,0 +17 468 . A <*> 0 . DP=35;DPR=34,0;I16=22,12,0,0,1274,51268,0,0,1955,114651,0,0,604,12904,0,0;QS=3,0;MQSB=0.997406;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,57,255:19:0:0:12,7,0,0:19,0 0,15,154:5:0:0:5,0,0,0:5,0 0,30,251:10:0:0:5,5,0,0:10,0 +17 469 . A <*> 0 . DP=35;DPR=34,0;I16=22,12,0,0,1285,52989,0,0,1955,114651,0,0,608,12940,0,0;QS=3,0;MQSB=0.997406;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,57,255:19:0:0:12,7,0,0:19,0 0,15,146:5:0:0:5,0,0,0:5,0 0,30,255:10:0:0:5,5,0,0:10,0 +17 470 . G <*> 0 . DP=35;DPR=34,0;I16=22,12,0,0,1281,51055,0,0,1955,114651,0,0,612,13016,0,0;QS=3,0;MQSB=0.997406;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,57,255:19:0:0:12,7,0,0:19,0 0,15,148:5:0:0:5,0,0,0:5,0 0,30,238:10:0:0:5,5,0,0:10,0 +17 471 . T <*> 0 . DP=36;DPR=33,0;I16=22,11,0,0,1239,49021,0,0,1918,113282,0,0,599,12825,0,0;QS=3,0;MQSB=0.915545;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,57,255:19:0:0:12,7,0,0:19,0 0,15,150:5:0:0:5,0,0,0:5,0 0,27,232:9:0:0:5,4,0,0:9,0 +17 472 . T <*> 0 . DP=35;DPR=33,0;I16=21,12,0,0,1245,48915,0,0,1926,113810,0,0,595,12559,0,0;QS=3,0;MQSB=0.988858;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,57,255:19:0:0:12,7,0,0:19,0 0,15,153:5:0:0:5,0,0,0:5,0 0,27,237:9:0:0:4,5,0,0:9,0 +17 473 . G <*> 0 . DP=35;DPR=33,0;I16=21,12,0,0,1307,53473,0,0,1926,113810,0,0,599,12651,0,0;QS=3,0;MQSB=0.988858;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,57,255:19:0:0:12,7,0,0:19,0 0,15,141:5:0:0:5,0,0,0:5,0 0,27,249:9:0:0:4,5,0,0:9,0 +17 474 . G <*> 0 . DP=36;DPR=34,0;I16=22,12,0,0,1284,51708,0,0,1986,117410,0,0,602,12734,0,0;QS=3,0;MQSB=0.986937;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,57,255:19:0:0:12,7,0,0:19,0 0,15,131:5:0:0:5,0,0,0:5,0 0,30,255:10:0:0:5,5,0,0:10,0 +17 475 . G <*> 0 . DP=36;DPR=35,0;I16=23,12,0,0,1311,51609,0,0,2015,118251,0,0,631,13485,0,0;QS=3,0;MQSB=0.998642;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,57,255:19:0:0:12,7,0,0:19,0 0,15,141:5:0:0:5,0,0,0:5,0 0,33,252:11:0:0:6,5,0,0:11,0 +17 476 . A <*> 0 . DP=36;DPR=35,0;I16=23,12,0,0,1312,52078,0,0,2015,118251,0,0,634,13606,0,0;QS=3,0;MQSB=0.998642;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,57,255:19:0:0:12,7,0,0:19,0 0,15,157:5:0:0:5,0,0,0:5,0 0,33,255:11:0:0:6,5,0,0:11,0 +17 477 . T <*> 0 . DP=36;DPR=35,0;I16=23,12,0,0,1318,52668,0,0,2015,118251,0,0,637,13773,0,0;QS=3,0;MQSB=0.998642;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,57,255:19:0:0:12,7,0,0:19,0 0,15,148:5:0:0:5,0,0,0:5,0 0,33,255:11:0:0:6,5,0,0:11,0 +17 478 . T <*> 0 . DP=38;DPR=37,0;I16=25,12,0,0,1338,51774,0,0,2135,125451,0,0,637,13833,0,0;QS=3,0;MQSB=0.999868;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,60,255:20:0:0:13,7,0,0:20,0 0,18,154:6:0:0:6,0,0,0:6,0 0,33,255:11:0:0:6,5,0,0:11,0 +17 479 . A <*> 0 . DP=38;DPR=37,0;I16=25,12,0,0,1420,57788,0,0,2135,125451,0,0,639,13935,0,0;QS=3,0;MQSB=0.999868;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,60,255:20:0:0:13,7,0,0:20,0 0,18,163:6:0:0:6,0,0,0:6,0 0,33,255:11:0:0:6,5,0,0:11,0 +17 480 . G <*> 0 . DP=37;DPR=36,0;I16=25,11,0,0,1438,60172,0,0,2075,121851,0,0,641,14029,0,0;QS=3,0;MQSB=0.999853;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,57,255:19:0:0:13,6,0,0:19,0 0,18,165:6:0:0:6,0,0,0:6,0 0,33,255:11:0:0:6,5,0,0:11,0 +17 481 . G <*> 0 . DP=37;DPR=36,0;I16=25,11,0,0,1392,55824,0,0,2075,121851,0,0,642,14112,0,0;QS=3,0;MQSB=0.999853;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,57,255:19:0:0:13,6,0,0:19,0 0,18,165:6:0:0:6,0,0,0:6,0 0,33,255:11:0:0:6,5,0,0:11,0 +17 482 . A <*> 0 . DP=37;DPR=35,0;I16=24,11,0,0,1352,55134,0,0,2015,118251,0,0,618,13608,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,57,255:19:0:0:13,6,0,0:19,0 0,15,143:5:0:0:5,0,0,0:5,0 0,33,255:11:0:0:6,5,0,0:11,0 +17 483 . G <*> 0 . DP=37;DPR=36,0;I16=24,12,0,0,1417,57747,0,0,2075,121851,0,0,642,14240,0,0;QS=3,0;MQSB=0.999437;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,57,255:19:0:0:12,7,0,0:19,0 0,18,165:6:0:0:6,0,0,0:6,0 0,33,255:11:0:0:6,5,0,0:11,0 +17 484 . A <*> 0 . DP=36;DPR=35,0;I16=24,11,0,0,1340,53992,0,0,2015,118251,0,0,643,14281,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:12,6,0,0:18,0 0,18,168:6:0:0:6,0,0,0:6,0 0,33,255:11:0:0:6,5,0,0:11,0 +17 485 . G <*> 0 . DP=35;DPR=35,0;I16=23,12,0,0,1329,51411,0,0,2015,118251,0,0,669,14931,0,0;QS=3,0;MQSB=0.998642;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:12,6,0,0:18,0 0,18,160:6:0:0:5,1,0,0:6,0 0,33,255:11:0:0:6,5,0,0:11,0 +17 486 . A <*> 0 . DP=34;DPR=34,0;I16=22,12,0,0,1311,51523,0,0,1955,114651,0,0,671,14989,0,0;QS=3,0;MQSB=0.997406;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:11,6,0,0:17,0 0,18,173:6:0:0:5,1,0,0:6,0 0,33,255:11:0:0:6,5,0,0:11,0 +17 487 . G <*> 0 . DP=34;DPR=34,0;I16=22,12,0,0,1306,50760,0,0,1955,114651,0,0,672,15030,0,0;QS=3,0;MQSB=0.997406;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:11,6,0,0:17,0 0,18,169:6:0:0:5,1,0,0:6,0 0,33,255:11:0:0:6,5,0,0:11,0 +17 488 . A <*> 0 . DP=35;DPR=34,0;I16=22,12,0,0,1274,48140,0,0,1986,117410,0,0,646,14380,0,0;QS=3,0;MQSB=0.986937;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:12,6,0,0:18,0 0,18,177:6:0:0:5,1,0,0:6,0 0,30,255:10:0:0:5,5,0,0:10,0 +17 489 . A <*> 0 . DP=35;DPR=35,0;I16=23,12,0,0,1264,46916,0,0,2015,118251,0,0,671,15015,0,0;QS=3,0;MQSB=0.998642;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:12,6,0,0:18,0 0,18,175:6:0:0:5,1,0,0:6,0 0,33,255:11:0:0:6,5,0,0:11,0 +17 490 . A <*> 0 . DP=36;DPR=36,0;I16=24,12,0,0,1332,50280,0,0,2075,121851,0,0,671,15061,0,0;QS=3,0;MQSB=0.999437;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:12,6,0,0:18,0 0,21,188:7:0:0:6,1,0,0:7,0 0,33,255:11:0:0:6,5,0,0:11,0 +17 491 . T <*> 0 . DP=36;DPR=36,0;I16=24,12,0,0,1284,46802,0,0,2075,121851,0,0,671,15093,0,0;QS=3,0;MQSB=0.999437;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:12,6,0,0:18,0 0,21,178:7:0:0:6,1,0,0:7,0 0,33,255:11:0:0:6,5,0,0:11,0 +17 492 . G <*> 0 . DP=35;DPR=33,0;I16=21,12,0,0,1252,48326,0,0,1926,113810,0,0,621,13859,0,0;QS=3,0;MQSB=0.988858;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:11,6,0,0:17,0 0,18,172:6:0:0:5,1,0,0:6,0 0,30,251:10:0:0:5,5,0,0:10,0 +17 493 . A <*> 0 . DP=34;DPR=33,0;I16=22,11,0,0,1273,49481,0,0,1926,113810,0,0,650,14672,0,0;QS=3,0;MQSB=0.981935;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:12,6,0,0:18,0 0,21,186:7:0:0:6,1,0,0:7,0 0,24,240:8:0:0:4,4,0,0:8,0 +17 494 . A <*> 0 . DP=34;DPR=34,0;I16=22,12,0,0,1326,52604,0,0,1986,117410,0,0,672,15182,0,0;QS=3,0;MQSB=0.986937;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:12,6,0,0:18,0 0,21,196:7:0:0:6,1,0,0:7,0 0,27,255:9:0:0:4,5,0,0:9,0 +17 495 . G <*> 0 . DP=34;DPR=33,0;I16=21,12,0,0,1255,48577,0,0,1926,113810,0,0,647,14611,0,0;QS=3,0;MQSB=0.988858;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:12,6,0,0:18,0 0,18,168:6:0:0:5,1,0,0:6,0 0,27,244:9:0:0:4,5,0,0:9,0 +17 496 . A <*> 0 . DP=34;DPR=34,0;I16=22,12,0,0,1250,46926,0,0,1986,117410,0,0,670,15220,0,0;QS=3,0;MQSB=0.986937;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:12,6,0,0:18,0 0,21,186:7:0:0:6,1,0,0:7,0 0,27,249:9:0:0:4,5,0,0:9,0 +17 497 . C <*> 0 . DP=34;DPR=34,0;I16=22,12,0,0,1250,47006,0,0,1986,117410,0,0,665,15087,0,0;QS=3,0;MQSB=0.986937;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:12,6,0,0:18,0 0,21,164:7:0:0:6,1,0,0:7,0 0,27,239:9:0:0:4,5,0,0:9,0 +17 498 . A <*> 0 . DP=34;DPR=34,0;I16=22,12,0,0,1286,49158,0,0,1986,117410,0,0,661,14987,0,0;QS=3,0;MQSB=0.986937;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:12,6,0,0:18,0 0,21,185:7:0:0:6,1,0,0:7,0 0,27,252:9:0:0:4,5,0,0:9,0 +17 499 . T <*> 0 . DP=34;DPR=34,0;I16=23,11,0,0,1224,45284,0,0,1986,117410,0,0,659,14919,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:12,5,0,0:17,0 0,21,183:7:0:0:6,1,0,0:7,0 0,30,255:10:0:0:5,5,0,0:10,0 +17 500 . A <*> 0 . DP=34;DPR=34,0;I16=23,11,0,0,1230,45152,0,0,1986,117410,0,0,657,14833,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:12,5,0,0:17,0 0,21,179:7:0:0:6,1,0,0:7,0 0,30,255:10:0:0:5,5,0,0:10,0 +17 501 . T <*> 0 . DP=33;DPR=33,0;I16=23,10,0,0,1241,47167,0,0,1926,113810,0,0,656,14778,0,0;QS=3,0;MQSB=0.972757;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:12,5,0,0:17,0 0,21,186:7:0:0:6,1,0,0:7,0 0,27,241:9:0:0:5,4,0,0:9,0 +17 502 . G <*> 0 . DP=33;DPR=33,0;I16=23,10,0,0,1215,45829,0,0,1926,113810,0,0,655,14753,0,0;QS=3,0;MQSB=0.972757;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:12,5,0,0:17,0 0,21,183:7:0:0:6,1,0,0:7,0 0,27,235:9:0:0:5,4,0,0:9,0 +17 503 . T <*> 0 . DP=34;DPR=34,0;I16=23,11,0,0,1194,43366,0,0,1986,117410,0,0,654,14758,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:12,6,0,0:18,0 0,21,177:7:0:0:6,1,0,0:7,0 0,27,234:9:0:0:5,4,0,0:9,0 +17 504 . C <*> 0 . DP=34;DPR=34,0;I16=23,11,0,0,1218,45552,0,0,1986,117410,0,0,651,14643,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:12,6,0,0:18,0 0,21,183:7:0:0:6,1,0,0:7,0 0,27,219:9:0:0:5,4,0,0:9,0 +17 505 . C <*> 0 . DP=35;DPR=34,0;I16=23,11,0,0,1207,44321,0,0,1986,117410,0,0,641,14509,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:12,6,0,0:18,0 0,21,189:7:0:0:6,1,0,0:7,0 0,27,221:9:0:0:5,4,0,0:9,0 +17 506 . A <*> 0 . DP=35;DPR=35,0;I16=24,11,0,0,1266,46776,0,0,2046,121010,0,0,646,14504,0,0;QS=3,0;MQSB=0.977529;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,57,255:19:0:0:13,6,0,0:19,0 0,21,188:7:0:0:6,1,0,0:7,0 0,27,231:9:0:0:5,4,0,0:9,0 +17 507 . C <*> 0 . DP=35;DPR=34,0;I16=23,11,0,0,1220,45016,0,0,1986,117410,0,0,635,14401,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:12,6,0,0:18,0 0,21,183:7:0:0:6,1,0,0:7,0 0,27,226:9:0:0:5,4,0,0:9,0 +17 508 . A <*> 0 . DP=34;DPR=34,0;I16=24,10,0,0,1204,44542,0,0,1986,117410,0,0,643,14491,0,0;QS=3,0;MQSB=0.970272;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:13,5,0,0:18,0 0,21,189:7:0:0:6,1,0,0:7,0 0,27,220:9:0:0:5,4,0,0:9,0 +17 509 . C <*> 0 . DP=34;DPR=34,0;I16=24,10,0,0,1272,48272,0,0,1986,117410,0,0,640,14430,0,0;QS=3,0;MQSB=0.970272;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:13,5,0,0:18,0 0,21,186:7:0:0:6,1,0,0:7,0 0,27,241:9:0:0:5,4,0,0:9,0 +17 510 . A <*> 0 . DP=34;DPR=33,0;I16=22,11,0,0,1194,44196,0,0,1926,113810,0,0,613,13773,0,0;QS=3,0;MQSB=0.981935;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:12,6,0,0:18,0 0,21,187:7:0:0:6,1,0,0:7,0 0,24,221:8:0:0:4,4,0,0:8,0 +17 511 . A <*> 0 . DP=34;DPR=34,0;I16=23,11,0,0,1222,45562,0,0,1986,117410,0,0,637,14395,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,57,255:19:0:0:13,6,0,0:19,0 0,21,195:7:0:0:6,1,0,0:7,0 0,24,233:8:0:0:4,4,0,0:8,0 +17 512 . A C,<*> 0 . DP=33;DPR=32,1,0;I16=22,10,0,1,1121,40793,13,169,1866,110210,60,3600,628,14340,9,81;QS=2.97719,0.022807,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.981935;BQB=1;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,39,255,51,255,255:18:1:0:12,5,0,1:17,1,0 0,21,183,21,183,183:7:0:0:6,1,0,0:7,0,0 0,24,231,24,231,231:8:0:0:4,4,0,0:8,0,0 +17 513 . A <*> 0 . DP=32;DPR=30,0;I16=20,10,0,0,1115,42183,0,0,1746,103010,0,0,598,13624,0,0;QS=3,0;MQSB=0.980594;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255:16:0:0:11,5,0,0:16,0 0,18,175:6:0:0:5,1,0,0:6,0 0,24,233:8:0:0:4,4,0,0:8,0 +17 514 . A T,<*> 0 . DP=32;DPR=29,1,0;I16=20,9,0,1,1066,40004,16,256,1686,99410,60,3600,586,13500,11,121;QS=2.97075,0.0292505,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.980594;BQB=1;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,31,255,45,255,255:16:1:0:11,4,0,1:15,1,0 0,18,171,18,171,171:6:0:0:5,1,0,0:6,0,0 0,24,235,24,235,235:8:0:0:4,4,0,0:8,0,0 +17 515 . C <*> 0 . DP=32;DPR=28,0;I16=18,10,0,0,1010,37294,0,0,1626,95810,0,0,561,12915,0,0;QS=3,0;MQSB=0.986018;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,42,255:14:0:0:9,5,0,0:14,0 0,18,167:6:0:0:5,1,0,0:6,0 0,24,211:8:0:0:4,4,0,0:8,0 +17 516 . C <*> 0 . DP=32;DPR=31,0;I16=21,10,0,0,1100,40570,0,0,1806,106610,0,0,612,13954,0,0;QS=3,0;MQSB=0.977926;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255:16:0:0:11,5,0,0:16,0 0,21,187:7:0:0:6,1,0,0:7,0 0,24,215:8:0:0:4,4,0,0:8,0 +17 517 . T <*> 0 . DP=33;DPR=33,0;I16=23,10,0,0,1269,49995,0,0,1926,113810,0,0,636,14626,0,0;QS=3,0;MQSB=0.972757;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:13,5,0,0:18,0 0,21,201:7:0:0:6,1,0,0:7,0 0,24,242:8:0:0:4,4,0,0:8,0 +17 518 . G <*> 0 . DP=34;DPR=34,0;I16=24,10,0,0,1247,46839,0,0,1986,117410,0,0,636,14696,0,0;QS=3,0;MQSB=0.970272;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,57,255:19:0:0:14,5,0,0:19,0 0,21,182:7:0:0:6,1,0,0:7,0 0,24,220:8:0:0:4,4,0,0:8,0 +17 519 . T <*> 0 . DP=36;DPR=36,0;I16=25,11,0,0,1283,46693,0,0,2106,124610,0,0,636,14742,0,0;QS=3,0;MQSB=0.975394;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,63,255:21:0:0:15,6,0,0:21,0 0,21,177:7:0:0:6,1,0,0:7,0 0,24,224:8:0:0:4,4,0,0:8,0 +17 520 . T <*> 0 . DP=36;DPR=35,0;I16=24,11,0,0,1238,44894,0,0,2046,121010,0,0,613,14193,0,0;QS=3,0;MQSB=0.977529;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,60,255:20:0:0:14,6,0,0:20,0 0,21,180:7:0:0:6,1,0,0:7,0 0,24,223:8:0:0:4,4,0,0:8,0 +17 521 . C <*> 0 . DP=34;DPR=34,0;I16=25,9,0,0,1280,49454,0,0,1986,117410,0,0,641,14875,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,60,255:20:0:0:15,5,0,0:20,0 0,21,191:7:0:0:6,1,0,0:7,0 0,21,204:7:0:0:4,3,0,0:7,0 +17 522 . A <*> 0 . DP=32;DPR=32,0;I16=24,8,0,0,1158,43228,0,0,1897,112969,0,0,646,14960,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,60,255:20:0:0:15,5,0,0:20,0 0,21,185:7:0:0:6,1,0,0:7,0 0,15,170:5:0:0:3,2,0,0:5,0 +17 523 . T G,<*> 0 . DP=32;DPR=31,1,0;I16=23,8,1,0,1184,45708,15,225,1837,109369,60,3600,626,14446,25,625;QS=2.9794,0.0206044,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.872525;BQB=1;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,44,255,57,255,255:20:1:0:14,5,1,0:19,1,0 0,21,191,21,191,191:7:0:0:6,1,0,0:7,0,0 0,15,166,15,166,166:5:0:0:3,2,0,0:5,0,0 +17 524 . T <*> 0 . DP=32;DPR=31,0;I16=24,7,0,0,1084,39474,0,0,1837,109369,0,0,629,14483,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,60,255:20:0:0:15,5,0,0:20,0 0,21,194:7:0:0:6,1,0,0:7,0 0,12,140:4:0:0:3,1,0,0:4,0 +17 525 . G <*> 0 . DP=32;DPR=31,0;I16=24,7,0,0,1181,45669,0,0,1837,109369,0,0,631,14495,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,60,255:20:0:0:15,5,0,0:20,0 0,21,188:7:0:0:6,1,0,0:7,0 0,12,129:4:0:0:3,1,0,0:4,0 +17 526 . C <*> 0 . DP=32;DPR=31,0;I16=24,7,0,0,1146,43950,0,0,1860,111600,0,0,633,14531,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,60,255:20:0:0:15,5,0,0:20,0 0,21,185:7:0:0:6,1,0,0:7,0 0,12,131:4:0:0:3,1,0,0:4,0 +17 527 . A <*> 0 . DP=33;DPR=32,0;I16=24,8,0,0,1209,46265,0,0,1897,112969,0,0,636,14634,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,57,255:19:0:0:14,5,0,0:19,0 0,21,194:7:0:0:6,1,0,0:7,0 0,18,181:6:0:0:4,2,0,0:6,0 +17 528 . G <*> 0 . DP=33;DPR=32,0;I16=24,8,0,0,1256,49824,0,0,1897,112969,0,0,634,14484,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,60,255:20:0:0:15,5,0,0:20,0 0,18,169:6:0:0:5,1,0,0:6,0 0,18,193:6:0:0:4,2,0,0:6,0 +17 529 . C <*> 0 . DP=32;DPR=31,0;I16=24,7,0,0,1148,44362,0,0,1837,109369,0,0,633,14357,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:14,4,0,0:18,0 0,21,187:7:0:0:6,1,0,0:7,0 0,18,184:6:0:0:4,2,0,0:6,0 +17 530 . T <*> 0 . DP=32;DPR=32,0;I16=25,7,0,0,1244,49168,0,0,1897,112969,0,0,657,14883,0,0;QS=3,0;MQSB=0.850154;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,57,255:19:0:0:15,4,0,0:19,0 0,21,196:7:0:0:6,1,0,0:7,0 0,18,202:6:0:0:4,2,0,0:6,0 +17 531 . T <*> 0 . DP=32;DPR=32,0;I16=25,7,0,0,1177,44171,0,0,1897,112969,0,0,654,14714,0,0;QS=3,0;MQSB=0.850154;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,57,255:19:0:0:15,4,0,0:19,0 0,21,181:7:0:0:6,1,0,0:7,0 0,18,193:6:0:0:4,2,0,0:6,0 +17 532 . T <*> 0 . DP=32;DPR=31,0;I16=24,7,0,0,1153,43543,0,0,1837,109369,0,0,630,14116,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:14,4,0,0:18,0 0,21,181:7:0:0:6,1,0,0:7,0 0,18,192:6:0:0:4,2,0,0:6,0 +17 533 . C <*> 0 . DP=32;DPR=31,0;I16=24,7,0,0,1142,43940,0,0,1837,109369,0,0,619,13649,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:14,4,0,0:18,0 0,21,178:7:0:0:6,1,0,0:7,0 0,18,180:6:0:0:4,2,0,0:6,0 +17 534 . T <*> 0 . DP=31;DPR=30,0;I16=24,6,0,0,1212,49426,0,0,1777,105769,0,0,615,13479,0,0;QS=3,0;MQSB=0.82403;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:14,3,0,0:17,0 0,21,205:7:0:0:6,1,0,0:7,0 0,18,205:6:0:0:4,2,0,0:6,0 +17 535 . A <*> 0 . DP=31;DPR=30,0;I16=24,6,0,0,1080,39870,0,0,1777,105769,0,0,611,13341,0,0;QS=3,0;MQSB=0.82403;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:14,3,0,0:17,0 0,21,194:7:0:0:6,1,0,0:7,0 0,18,189:6:0:0:4,2,0,0:6,0 +17 536 . C <*> 0 . DP=31;DPR=31,0;I16=24,7,0,0,1097,40707,0,0,1837,109369,0,0,631,13809,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:14,4,0,0:18,0 0,21,184:7:0:0:6,1,0,0:7,0 0,18,157:6:0:0:4,2,0,0:6,0 +17 537 . C <*> 0 . DP=31;DPR=29,0;I16=22,7,0,0,1034,38564,0,0,1717,102169,0,0,587,12861,0,0;QS=3,0;MQSB=0.854582;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255:16:0:0:12,4,0,0:16,0 0,21,172:7:0:0:6,1,0,0:7,0 0,18,183:6:0:0:4,2,0,0:6,0 +17 538 . A <*> 0 . DP=31;DPR=31,0;I16=24,7,0,0,1138,42478,0,0,1837,109369,0,0,620,13536,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:14,4,0,0:18,0 0,21,189:7:0:0:6,1,0,0:7,0 0,18,181:6:0:0:4,2,0,0:6,0 +17 539 . T <*> 0 . DP=31;DPR=31,0;I16=24,7,0,0,1134,42070,0,0,1837,109369,0,0,614,13422,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:14,4,0,0:18,0 0,21,178:7:0:0:6,1,0,0:7,0 0,18,181:6:0:0:4,2,0,0:6,0 +17 540 . C <*> 0 . DP=31;DPR=31,0;I16=24,7,0,0,1148,43768,0,0,1837,109369,0,0,608,13340,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:14,4,0,0:18,0 0,21,177:7:0:0:6,1,0,0:7,0 0,18,178:6:0:0:4,2,0,0:6,0 +17 541 . A <*> 0 . DP=32;DPR=30,0;I16=24,6,0,0,1083,40483,0,0,1777,105769,0,0,551,11991,0,0;QS=3,0;MQSB=0.82403;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:13,4,0,0:17,0 0,24,180:8:0:0:7,1,0,0:8,0 0,15,150:5:0:0:4,1,0,0:5,0 +17 542 . C <*> 0 . DP=33;DPR=31,0;I16=25,6,0,0,1123,41759,0,0,1837,109369,0,0,570,12552,0,0;QS=3,0;MQSB=0.822578;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:14,3,0,0:17,0 0,24,172:8:0:0:7,1,0,0:8,0 0,18,174:6:0:0:4,2,0,0:6,0 +17 543 . C <*> 0 . DP=34;DPR=34,0;I16=25,9,0,0,1219,45959,0,0,1986,117410,0,0,601,13245,0,0;QS=3,0;MQSB=0.621145;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,57,255:19:0:0:14,5,0,0:19,0 0,27,194:9:0:0:7,2,0,0:9,0 0,18,188:6:0:0:4,2,0,0:6,0 +17 544 . A <*> 0 . DP=33;DPR=32,0;I16=24,8,0,0,1170,43898,0,0,1866,110210,0,0,570,12506,0,0;QS=3,0;MQSB=0.579578;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:13,5,0,0:18,0 0,24,192:8:0:0:7,1,0,0:8,0 0,18,180:6:0:0:4,2,0,0:6,0 +17 545 . A <*> 0 . DP=33;DPR=33,0;I16=25,8,0,0,1174,43602,0,0,1926,113810,0,0,587,12951,0,0;QS=3,0;MQSB=0.576102;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,57,255:19:0:0:14,5,0,0:19,0 0,24,190:8:0:0:7,1,0,0:8,0 0,18,184:6:0:0:4,2,0,0:6,0 +17 546 . A <*> 0 . DP=32;DPR=32,0;I16=24,8,0,0,1126,41444,0,0,1866,110210,0,0,580,12802,0,0;QS=3,0;MQSB=0.579578;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,57,255:19:0:0:14,5,0,0:19,0 0,21,166:7:0:0:6,1,0,0:7,0 0,18,193:6:0:0:4,2,0,0:6,0 +17 547 . A <*> 0 . DP=32;DPR=31,0;I16=24,7,0,0,1129,42381,0,0,1806,106610,0,0,547,12009,0,0;QS=3,0;MQSB=0.525788;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:14,4,0,0:18,0 0,21,180:7:0:0:6,1,0,0:7,0 0,18,195:6:0:0:4,2,0,0:6,0 +17 548 . A <*> 0 . DP=33;DPR=32,0;I16=23,9,0,0,1153,42673,0,0,1866,110210,0,0,561,12489,0,0;QS=3,0;MQSB=0.628357;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:13,5,0,0:18,0 0,21,181:7:0:0:6,1,0,0:7,0 0,21,211:7:0:0:4,3,0,0:7,0 +17 549 . T G,<*> 0 . DP=32;DPR=30,1,0;I16=22,8,0,1,1101,40987,20,400,1746,103010,60,3600,530,11716,25,625;QS=2.96748,0.0325203,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.632337;BQB=1;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,31,255,48,255,255:17:1:0:12,4,0,1:16,1,0 0,21,168,21,168,168:7:0:0:6,1,0,0:7,0,0 0,21,208,21,208,208:7:0:0:4,3,0,0:7,0,0 +17 550 . T <*> 0 . DP=32;DPR=31,0;I16=22,9,0,0,1052,37298,0,0,1806,106610,0,0,548,12176,0,0;QS=3,0;MQSB=0.632337;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:12,5,0,0:17,0 0,21,150:7:0:0:6,1,0,0:7,0 0,21,220:7:0:0:4,3,0,0:7,0 +17 551 . G <*> 0 . DP=31;DPR=31,0;I16=22,9,0,0,1121,41639,0,0,1806,106610,0,0,541,12045,0,0;QS=3,0;MQSB=0.632337;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:12,5,0,0:17,0 0,21,172:7:0:0:6,1,0,0:7,0 0,21,208:7:0:0:4,3,0,0:7,0 +17 552 . C <*> 0 . DP=30;DPR=30,0;I16=21,9,0,0,1093,41365,0,0,1746,103010,0,0,535,11947,0,0;QS=3,0;MQSB=0.636601;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255:16:0:0:11,5,0,0:16,0 0,21,167:7:0:0:6,1,0,0:7,0 0,21,208:7:0:0:4,3,0,0:7,0 +17 553 . A <*> 0 . DP=30;DPR=28,0;I16=20,8,0,0,981,35387,0,0,1626,95810,0,0,485,10831,0,0;QS=3,0;MQSB=0.596163;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,45,255:15:0:0:10,5,0,0:15,0 0,18,150:6:0:0:5,1,0,0:6,0 0,21,194:7:0:0:5,2,0,0:7,0 +17 554 . A <*> 0 . DP=30;DPR=28,0;I16=19,9,0,0,975,35601,0,0,1626,95810,0,0,488,10906,0,0;QS=3,0;MQSB=0.646113;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,45,255:15:0:0:10,5,0,0:15,0 0,15,139:5:0:0:4,1,0,0:5,0 0,24,211:8:0:0:5,3,0,0:8,0 +17 555 . A <*> 0 . DP=30;DPR=30,0;I16=20,10,0,0,1024,36526,0,0,1746,103010,0,0,514,11392,0,0;QS=3,0;MQSB=0.679025;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:11,6,0,0:17,0 0,18,150:6:0:0:5,1,0,0:6,0 0,21,211:7:0:0:4,3,0,0:7,0 +17 556 . C <*> 0 . DP=29;DPR=29,0;I16=20,9,0,0,1055,39195,0,0,1709,101641,0,0,509,11219,0,0;QS=3,0;MQSB=0.894839;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:11,6,0,0:17,0 0,18,158:6:0:0:5,1,0,0:6,0 0,18,186:6:0:0:4,2,0,0:6,0 +17 557 . A <*> 0 . DP=27;DPR=27,0;I16=18,9,0,0,987,36749,0,0,1589,94441,0,0,506,11074,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,45,255:15:0:0:9,6,0,0:15,0 0,18,157:6:0:0:5,1,0,0:6,0 0,18,186:6:0:0:4,2,0,0:6,0 +17 558 . A <*> 0 . DP=27;DPR=26,0;I16=18,8,0,0,948,35808,0,0,1560,93600,0,0,477,10281,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,45,255:15:0:0:9,6,0,0:15,0 0,15,143:5:0:0:5,0,0,0:5,0 0,18,177:6:0:0:4,2,0,0:6,0 +17 559 . C A,<*> 0 . DP=27;DPR=25,1,0;I16=17,8,0,1,908,33726,14,196,1500,90000,29,841,448,9516,25,625;QS=2.92708,0.0729167,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.90038;BQB=1;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,42,255,42,255,255:14:0:0:8,6,0,0:14,0,0 0,4,116,15,119,123:6:1:0:5,0,0,1:5,1,0 0,18,169,18,169,169:6:0:0:4,2,0,0:6,0,0 +17 560 . C <*> 0 . DP=28;DPR=28,0;I16=19,9,0,0,992,36552,0,0,1649,98041,0,0,494,10654,0,0;QS=3,0;MQSB=0.896555;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,45,255:15:0:0:9,6,0,0:15,0 0,18,160:6:0:0:5,1,0,0:6,0 0,21,181:7:0:0:5,2,0,0:7,0 +17 561 . A <*> 0 . DP=28;DPR=27,0;I16=18,9,0,0,963,35455,0,0,1589,94441,0,0,466,9946,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,42,255:14:0:0:8,6,0,0:14,0 0,18,158:6:0:0:5,1,0,0:6,0 0,21,194:7:0:0:5,2,0,0:7,0 +17 562 . C <*> 0 . DP=28;DPR=27,0;I16=18,9,0,0,1006,38392,0,0,1589,94441,0,0,463,9893,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,42,255:14:0:0:8,6,0,0:14,0 0,18,153:6:0:0:5,1,0,0:6,0 0,21,187:7:0:0:5,2,0,0:7,0 +17 563 . A <*> 0 . DP=27;DPR=26,0;I16=17,9,0,0,893,32413,0,0,1529,90841,0,0,460,9820,0,0;QS=3,0;MQSB=0.90038;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,42,255:14:0:0:8,6,0,0:14,0 0,15,149:5:0:0:4,1,0,0:5,0 0,21,179:7:0:0:5,2,0,0:7,0 +17 564 . C <*> 0 . DP=27;DPR=27,0;I16=18,9,0,0,859,28747,0,0,1589,94441,0,0,482,10402,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,45,255:15:0:0:9,6,0,0:15,0 0,15,121:5:0:0:4,1,0,0:5,0 0,21,182:7:0:0:5,2,0,0:7,0 +17 565 . G <*> 0 . DP=30;DPR=26,0;I16=17,9,0,0,818,26928,0,0,1560,93600,0,0,454,9764,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,45,255:15:0:0:9,6,0,0:15,0 0,12,96:4:0:0:3,1,0,0:4,0 0,21,154:7:0:0:5,2,0,0:7,0 +17 566 . C <*> 0 . DP=29;DPR=26,0;I16=15,11,0,0,903,33405,0,0,1529,90841,0,0,424,9084,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,45,255:15:0:0:7,8,0,0:15,0 0,15,155:5:0:0:3,2,0,0:5,0 0,18,167:6:0:0:5,1,0,0:6,0 +17 567 . C <*> 0 . DP=30;DPR=27,0;I16=15,12,0,0,932,33774,0,0,1589,94441,0,0,462,10178,0,0;QS=3,0;MQSB=0.935229;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,45,255:15:0:0:7,8,0,0:15,0 0,15,155:5:0:0:3,2,0,0:5,0 0,21,196:7:0:0:5,2,0,0:7,0 +17 568 . C <*> 0 . DP=29;DPR=28,0;I16=15,13,0,0,1057,40817,0,0,1649,98041,0,0,482,10438,0,0;QS=3,0;MQSB=0.942064;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255:16:0:0:8,8,0,0:16,0 0,18,183:6:0:0:3,3,0,0:6,0 0,18,189:6:0:0:4,2,0,0:6,0 +17 569 . T <*> 0 . DP=30;DPR=28,0;I16=16,12,0,0,1056,41296,0,0,1649,98041,0,0,493,10655,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,45,255:15:0:0:8,7,0,0:15,0 0,18,190:6:0:0:3,3,0,0:6,0 0,21,213:7:0:0:5,2,0,0:7,0 +17 570 . T <*> 0 . DP=30;DPR=28,0;I16=16,12,0,0,954,34972,0,0,1680,100800,0,0,472,10086,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255:16:0:0:8,8,0,0:16,0 0,15,157:5:0:0:3,2,0,0:5,0 0,21,195:7:0:0:5,2,0,0:7,0 +17 571 . C <*> 0 . DP=31;DPR=29,0;I16=17,12,0,0,1061,40675,0,0,1740,104400,0,0,472,10158,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:9,8,0,0:17,0 0,15,155:5:0:0:3,2,0,0:5,0 0,21,193:7:0:0:5,2,0,0:7,0 +17 572 . A <*> 0 . DP=31;DPR=30,0;I16=18,12,0,0,1102,42642,0,0,1769,105241,0,0,499,10887,0,0;QS=3,0;MQSB=0.929991;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:9,8,0,0:17,0 0,21,203:7:0:0:4,3,0,0:7,0 0,18,175:6:0:0:5,1,0,0:6,0 +17 573 . A <*> 0 . DP=31;DPR=30,0;I16=18,12,0,0,1057,38473,0,0,1769,105241,0,0,501,10975,0,0;QS=3,0;MQSB=0.929991;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:9,8,0,0:17,0 0,21,199:7:0:0:4,3,0,0:7,0 0,18,178:6:0:0:5,1,0,0:6,0 +17 574 . C A,<*> 0 . DP=31;DPR=29,1,0;I16=18,11,0,1,1088,41328,15,225,1740,104400,29,841,478,10422,25,625;QS=2.94071,0.0592885,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.929991;BQB=1;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255,48,255,255:16:0:0:8,8,0,0:16,0,0 0,9,170,21,173,177:8:1:0:5,2,0,1:7,1,0 0,18,173,18,173,173:6:0:0:5,1,0,0:6,0,0 +17 575 . T <*> 0 . DP=30;DPR=26,0;I16=16,10,0,0,1024,41260,0,0,1560,93600,0,0,448,9842,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,42,255:14:0:0:7,7,0,0:14,0 0,21,209:7:0:0:5,2,0,0:7,0 0,15,163:5:0:0:4,1,0,0:5,0 +17 576 . G <*> 0 . DP=30;DPR=29,0;I16=17,12,0,0,1047,40077,0,0,1709,101641,0,0,507,11087,0,0;QS=3,0;MQSB=0.931617;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255:16:0:0:8,8,0,0:16,0 0,24,208:8:0:0:5,3,0,0:8,0 0,15,151:5:0:0:4,1,0,0:5,0 +17 577 . G <*> 0 . DP=30;DPR=28,0;I16=16,12,0,0,999,37747,0,0,1649,98041,0,0,489,10755,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,45,255:15:0:0:7,8,0,0:15,0 0,24,204:8:0:0:5,3,0,0:8,0 0,15,146:5:0:0:4,1,0,0:5,0 +17 578 . G <*> 0 . DP=29;DPR=29,0;I16=16,13,0,0,975,34803,0,0,1709,101641,0,0,520,11286,0,0;QS=3,0;MQSB=0.940317;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255:16:0:0:7,9,0,0:16,0 0,24,198:8:0:0:5,3,0,0:8,0 0,15,151:5:0:0:4,1,0,0:5,0 +17 579 . G <*> 0 . DP=30;DPR=28,0;I16=15,13,0,0,1028,38752,0,0,1649,98041,0,0,484,10514,0,0;QS=3,0;MQSB=0.942064;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,48,255:16:0:0:8,8,0,0:16,0 0,24,224:8:0:0:4,4,0,0:8,0 0,12,145:4:0:0:3,1,0,0:4,0 +17 580 . A C,<*> 0 . DP=30;DPR=29,1,0;I16=15,14,1,0,1060,39178,16,256,1709,101641,60,3600,510,11078,17,289;QS=2.97338,0.0266223,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.946202;BQB=1;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,34,255,48,255,255:17:1:0:7,9,1,0:16,1,0 0,24,221,24,221,221:8:0:0:4,4,0,0:8,0,0 0,15,155,15,155,155:5:0:0:4,1,0,0:5,0,0 +17 581 . A <*> 0 . DP=31;DPR=31,0;I16=16,15,0,0,1083,39215,0,0,1829,108841,0,0,530,11384,0,0;QS=3,0;MQSB=0.951229;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:8,10,0,0:18,0 0,24,223:8:0:0:4,4,0,0:8,0 0,15,153:5:0:0:4,1,0,0:5,0 +17 582 . C <*> 0 . DP=31;DPR=30,0;I16=15,15,0,0,1080,39870,0,0,1769,105241,0,0,519,11211,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:7,10,0,0:17,0 0,24,207:8:0:0:4,4,0,0:8,0 0,15,151:5:0:0:4,1,0,0:5,0 +17 583 . T <*> 0 . DP=30;DPR=30,0;I16=16,14,0,0,1136,43996,0,0,1769,105241,0,0,539,11523,0,0;QS=3,0;MQSB=0.946202;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:8,9,0,0:17,0 0,24,238:8:0:0:4,4,0,0:8,0 0,15,163:5:0:0:4,1,0,0:5,0 +17 584 . C <*> 0 . DP=31;DPR=29,0;I16=16,13,0,0,1051,39351,0,0,1709,101641,0,0,499,10619,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:8,9,0,0:17,0 0,21,207:7:0:0:4,3,0,0:7,0 0,15,157:5:0:0:4,1,0,0:5,0 +17 585 . A <*> 0 . DP=31;DPR=31,0;I16=17,14,0,0,1096,39866,0,0,1798,106082,0,0,549,11751,0,0;QS=3,0;MQSB=0.998229;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:9,9,0,0:18,0 0,24,211:8:0:0:4,4,0,0:8,0 0,15,157:5:0:0:4,1,0,0:5,0 +17 586 . T <*> 0 . DP=31;DPR=30,0;I16=16,14,0,0,1081,39839,0,0,1738,102482,0,0,546,11796,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:8,9,0,0:17,0 0,24,212:8:0:0:4,4,0,0:8,0 0,15,156:5:0:0:4,1,0,0:5,0 +17 587 . C <*> 0 . DP=31;DPR=30,0;I16=17,13,0,0,1070,39402,0,0,1769,105241,0,0,532,11350,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:9,9,0,0:18,0 0,21,201:7:0:0:4,3,0,0:7,0 0,15,155:5:0:0:4,1,0,0:5,0 +17 588 . A <*> 0 . DP=31;DPR=31,0;I16=17,14,0,0,1126,41642,0,0,1798,106082,0,0,562,12140,0,0;QS=3,0;MQSB=0.998229;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:9,9,0,0:18,0 0,24,222:8:0:0:4,4,0,0:8,0 0,15,164:5:0:0:4,1,0,0:5,0 +17 589 . A <*> 0 . DP=31;DPR=31,0;I16=17,14,0,0,1157,43973,0,0,1798,106082,0,0,568,12340,0,0;QS=3,0;MQSB=0.998229;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:9,9,0,0:18,0 0,24,236:8:0:0:4,4,0,0:8,0 0,15,165:5:0:0:4,1,0,0:5,0 +17 590 . C <*> 0 . DP=32;DPR=30,0;I16=16,14,0,0,1094,41302,0,0,1769,105241,0,0,549,11951,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:9,9,0,0:18,0 0,18,192:6:0:0:3,3,0,0:6,0 0,18,175:6:0:0:4,2,0,0:6,0 +17 591 . A <*> 0 . DP=31;DPR=31,0;I16=16,15,0,0,1165,44163,0,0,1798,106082,0,0,579,12695,0,0;QS=3,0;MQSB=0.999805;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:9,9,0,0:18,0 0,21,209:7:0:0:3,4,0,0:7,0 0,18,188:6:0:0:4,2,0,0:6,0 +17 592 . A <*> 0 . DP=31;DPR=30,0;I16=15,15,0,0,1114,42144,0,0,1738,102482,0,0,571,12651,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:8,9,0,0:17,0 0,21,215:7:0:0:3,4,0,0:7,0 0,18,182:6:0:0:4,2,0,0:6,0 +17 593 . C <*> 0 . DP=31;DPR=29,0;I16=15,14,0,0,1065,39889,0,0,1709,101641,0,0,550,12132,0,0;QS=3,0;MQSB=0.954405;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:8,9,0,0:17,0 0,18,191:6:0:0:3,3,0,0:6,0 0,18,174:6:0:0:4,2,0,0:6,0 +17 594 . A <*> 0 . DP=33;DPR=32,0;I16=16,16,0,0,1163,42917,0,0,1858,109682,0,0,572,12672,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:8,9,0,0:17,0 0,21,205:7:0:0:3,4,0,0:7,0 0,24,212:8:0:0:5,3,0,0:8,0 +17 595 . A <*> 0 . DP=33;DPR=33,0;I16=17,16,0,0,1130,39996,0,0,1918,113282,0,0,589,12905,0,0;QS=3,0;MQSB=0.999838;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:9,9,0,0:18,0 0,21,198:7:0:0:3,4,0,0:7,0 0,24,213:8:0:0:5,3,0,0:8,0 +17 596 . A <*> 0 . DP=33;DPR=32,0;I16=16,16,0,0,1059,37039,0,0,1858,109682,0,0,590,12952,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:8,9,0,0:17,0 0,21,169:7:0:0:3,4,0,0:7,0 0,24,230:8:0:0:5,3,0,0:8,0 +17 597 . C <*> 0 . DP=33;DPR=33,0;I16=17,16,0,0,1196,44890,0,0,1918,113282,0,0,592,12990,0,0;QS=3,0;MQSB=0.999838;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,54,255:18:0:0:9,9,0,0:18,0 0,21,204:7:0:0:3,4,0,0:7,0 0,24,220:8:0:0:5,3,0,0:8,0 +17 598 . T <*> 0 . DP=33;DPR=32,0;I16=16,16,0,0,1214,47104,0,0,1858,109682,0,0,593,13013,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:8,9,0,0:17,0 0,21,217:7:0:0:3,4,0,0:7,0 0,24,239:8:0:0:5,3,0,0:8,0 +17 599 . T <*> 0 . DP=33;DPR=33,0;I16=16,17,0,0,1183,43669,0,0,1918,113282,0,0,599,13095,0,0;QS=3,0;MQSB=0.999838;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:8,9,0,0:17,0 0,21,197:7:0:0:3,4,0,0:7,0 0,27,247:9:0:0:5,4,0,0:9,0 +17 600 . G <*> 0 . DP=32;DPR=32,0;I16=15,17,0,0,1174,44066,0,0,1858,109682,0,0,601,13145,0,0;QS=3,0;MQSB=0.999287;MQ0F=0 PL:DP:DV:SP:DP4:DPR 0,51,255:17:0:0:8,9,0,0:17,0 0,21,194:7:0:0:3,4,0,0:7,0 0,24,232:8:0:0:4,4,0,0:8,0 diff --git a/test/mpileup/mpileup.4.sam b/test/mpileup/mpileup.4.sam new file mode 100644 index 0000000..46903ab --- /dev/null +++ b/test/mpileup/mpileup.4.sam @@ -0,0 +1,238 @@ +@HD VN:1.0 SO:coordinate +@SQ SN:17 LN:4200 M5:a9a06ca09c111789d92723fbf39820f6 AS:NCBI37 SP:Human +@RG ID:ERR229776 LB:HG00102_I_bc_pelib_1019 SM:HG99999 PI:497 CN:MPIMG PL:ILLUMINA DS:SRP001294 +ERR229776.22049853 163 17 1 29 80S21M = 115 213 AGGCTCAGACTCCTTTCTCTATGACAGGGAGGTCATGTGCAGGCTGGAGAAGGGGACAAGAGGGCCCCAACTTCTTTGCAAAGCTTCTCACCCTGTTCCTG BDBDHECFF@D=DA>CIJIF8E>HBEEBH@AA8>GH@BIJI;?CC95@@?*2-67=6?$6ABDGD6GGHKGEGHIJIH=BFIKI:DEADBH>CFIE MD:Z:21 RG:Z:ERR229776 AM:i:29 NM:i:0 SM:i:29 MQ:i:29 XT:A:M BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ihg\aehjhYcd`cag]behd +ERR229776.4635304 99 17 1 29 9S92M = 250 348 TTCTTTGCAAAGCTTCTCACCCTGTTCCTGCATAGATAATTGCATGACAATTGCCTTGTCCCTGCTGAATGTGCTCTGGGGTCTCTGGGGTCTCACCCACG BFFKGHHHIKIIIKIKLKIILHMKJJLLMILJJJMLJJNKLLMKKJLJKNKLKILNKLKMLINLMNLMNKJJKLNKMKFAEHGMKPLHFGJIMIKFFFE@; MD:Z:92 RG:Z:ERR229776 AM:i:29 NM:i:0 SM:i:29 MQ:i:29 XT:A:M BQ:Z:@@@@@@@@@jhhhjhjkjhhkgljiikklhkiiilkiimjkkljjikijmjkjhkmjkjlkhmklmklmjiijkmjlje`dgfljokgefihlhjeeed_Z +ERR229776.76124411 163 17 1 29 12S89M = 253 351 AACTTCTTTGCAAAGCTTCTCACCCTGTTCCTGCATAGATAATTGCATGACAATTGCCTTGTCCCTGCTGAATGTGCTCTGGGGTCTCTGGGGTCTCACCC @BDIFEFFEBBGJIHGJHEIJHGJJKIIIIJKHHIIIJKICKHE@>1;<=E?CG?F X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@H +ERR229776.71066602 99 17 35 60 101M = 291 355 ATGACAATTGCCTTGTCCCTGCTGAATGTGCTCTGGGGTCTCTGGGGTCTCACCCACGACCAACTCCCTGGGCCTGGCACCAGGGAGCTTAACAAACATCT BEFHDHJHHHFGLIJIJKKLJKLKKMJIIHJLKMJJLMGGLJMJMMMEJMMKKMMKJ?LKLJMHNJIIMHCFHGMFCIJDHJICAIDJJFIHGGIBBHEEI X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@E +ERR229776.57643739 113 17 39 37 101M * 0 0 CAATTGCCTTGTCCCTGCTGAATGTGCTCTGGGGTCTCTGGGGTCTCACCCACGACCAACTCCCTGGGCCTGGCACCAGGGAGCTTAACAAACATCTGTCC DEEFHE@C?HCHHAIJIIJIHCJEIE;JHFEEFHKFJFJIEGIJGH>9KJD@;EFCJIFA=JFICKIDCFJGFC?IIJHHHKHB@IICIICGCGJGDDH?? X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.24343576 163 17 62 60 101M = 322 360 GTGCTCTGGGGTCTCTGGGGTCTCACCCACGACCAACTCCCTGGGCCTGGCACCAGGGAGCTTAACAAACATCTGTCCAGCGAATACCTGCATCCCTAGAA @DCDHCFB>,,FGDGFHGC@FHFIHGIKH@2JGH@JGJ?EJHCA5?BLIHEJHIGFEB@BG;BBEDGIEDGGGL;FGFI;A37F9F2=@JCDKHJGAIGFEEEE X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.48988007 99 17 115 60 101M = 371 356 CAGGGAGCTTAACAAACATCTGTCCAGCGAATACCTGCATCCCTAGAAGTGAAGCCACCGCCCAAAGACACGCCCATGTCCAGCTTAACCTGCATCCCTAG ?GDCCIGFKGFKGHKKHGIKJIIKGJHIACKFGHCKHJJJFIILGFGMK@CKFIHHJHI>JIFJMEGADJG>FEHJIIIFHJHIMDHKGIH?CJGGFFIE8 X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.22049853 83 17 115 29 1S100M = 1 -213 CCAGGGAGCTTAACAAACATCTGTCCAGCGAATACCTGCATCCCTAGAAGTGAAGCCACCGCCCAAAGACACGCCCATGTCCAGCTTAACCTGCATCCCTA ##IDEBEBHKIDCIFDIFGKD?EHA>BA;GJHIABEGEFGIBDGIKGJMGJIJKHGHKJALJJIJ@DCECE>EIIIHHIKDEFHIEHGHHGHGFEECCD@7 X0:i:1 X1:i:0 XC:i:100 MD:Z:100 RG:Z:ERR999999 AM:i:29 NM:i:0 SM:i:29 MQ:i:29 XT:A:U BQ:Z:@@B@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.6535575 163 17 136 60 101M = 400 364 GTCCAGCGAATACCTGCATCCCTAGAAGTGAAGCCACCGCCCAAAGACACGCCCCTGTCCAGCTTAACCTGCATCCCTAGAAGTGAAGGCACCGCCCAAAG @:9D&@9/0<98DBCCGCDG:?E=>D><+/;7A:=HE71)61>4:KDDIKLJJGJH=6GAIGEIHCHGB@?>HBFHGHBGDFKFGKHGFCFFGBBEJFIJMIFIHJJJLIDFF@HDKHEHGFEHLHHDEFDB X0:i:1 X1:i:0 XC:i:99 MD:Z:99 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A +ERR229776.74734077 163 17 164 60 101M = 421 357 TGAAGCCACCGCCCAAAGACACGCCCATGTCCAGCTTAACCTGCATCCCTAGAAGTGAAGGCGCCGCCCAAAGCCACGCCCATGTCCAGCTTATTCTGCCC 7+>C1A5?-3&B<:EA:(86>A4F8=B<7>7D52@7=>CAE5DK.DCF>(-706B=ACA>D<@IE4:D;CG;@BH9@GH@CCJ@G=B@;ED9E@BHDBFHGI;5ABFHFIG=FCE/=GHHEJGJF X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@H +ERR229776.86942903 99 17 232 60 71M1I29M = 471 339 CAAAGACACGCCCATGTCCAGCTTATTCTGCCCAGTTCCTCTCCAGAAAGGCTGCATGGTTGACACACAGTAGCCTGCGACAAAGCTGAATGCTATCATTT AGHIGIEGD>BGHFHHIKKILKMIIIHIKHJKLCEFJJFMDLJIFHKLLKDJGBEGGJ?@GFIIKIH?GGHDDACIB?>DDJFGII1?,9ED*@>D@FCE= X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR999999 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C@ +ERR229776.4635304 147 17 250 29 53M1I47M = 1 -348 CAGCTTATTCTGCCCAGTTCCTCTCCAGAAAGGCTGCATGGTTGACACACAGTAGCCTGCGACAAAGCTGAATGCTATCATTTAAAAACTCCTTGCTGGTT EIGGGHHHHCJICGIMGCJGHKCFDJOJJKKIJKKKJIKJJMIIJJJHEHIGILLLLGLBGDJJJLKGIKHGIIKHHJHHKIFHHCG;HFBCGFBEFCDGB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR999999 AM:i:29 NM:i:1 SM:i:29 MQ:i:29 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@IG +ERR229776.76124411 83 17 253 29 50M1I50M = 1 -351 CTTATTCTGCCCAGTTCCTCTCCAGAAAGGCTGCATGGTTGACACACAGTAGCCTGCGACAAAGCTGAATGCTATCATTTAAAAACTCCTTGCTGGTTTGA DDFFFGHJIGHINGDIGDJIJAINKELOIJLKKKKKMJLKKGJKJKLNKKNMMMKLBLJLLLNMMJKKJKKJJJKKJLLIJJHE@KJJJKFHIHFEIIHFB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR999999 AM:i:29 NM:i:1 SM:i:29 MQ:i:29 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.72556128 147 17 262 60 41M1I59M = 22 -339 CCCAGTTCCTCTCCAGAAAGGCTGCATGGTTGACACACAGTAGCCTGCGACAAAGCTGAATGCTATCATTTAAAAACTCCTTGCTGGTTTGAGAGGCAGAA DDFJEGJGC@IKEINIFFMHKHIJKKKIIMJKJJJLKKMJJLKKMJLCKKFKKMLLJKJIIKKIIKJHKLGHIGC>HHIJKFHHHGGIJGBEEJAEEIFEB X0:i:1 X1:i:0 MD:Z:100 RG:Z:ERR999999 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:CBA@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@GG +ERR229776.73749010 147 17 283 60 5S20M1I75M = 28 -349 AAAGGCTGCATGGTTGACACACAGTAGCCTGCGACAAAGCTGAATGCTATCATTTAAAAACTCCTTGCTGGTTTGAGAGGCAGAAAATGATATCTCATAGT ######G?<7G9;+@-DEI=CHOHKOFBHE9BHKFE>JHDH9?GHFDCBKCIHA;E=C;9>@A7HA?;AGADHBGHGG@@:>8HG?D9DF6/;@=>:BBA;FEFGH:A7E<&>HAJEIEKKKJGMIJGILKMGNLLKLKIEIJHDIEFE X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@G +ERR229776.65476258 99 17 324 60 101M = 548 324 TATCATTTAAAAACTCCTTGCTGGTTTGAGAGGCAGAAAATGATATCTCATAGTTGCTTTACTTTGCATATTTTAAAATTGTGACTTTCATGGCATAAATA BFFFGHHHHKIJKELKKKJJJLKLIIJIKLLJJLJMLMMNKLLKFJMNMKKJMKKLMNLLKKNLKLMKKKKLLKJNNNLILKLMJNLLKLKIEIKHGHGFE X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@G +ERR229776.44063798 163 17 331 60 101M = 608 377 TAAAAACTCCTTGCTGGTTTGAGAGGCAGAAAATGATATCTCATAGTTGCTTTACTTTGCATATTTTAAAATTGTGACTTTCATGGCATAAATAATACTGG @92:9C:E>:EFG>H@ X0:i:1 X1:i:0 MD:Z:0A100 RG:Z:ERR999999 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:ZS@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.59467859 147 17 359 60 101M = 159 -300 GAAAATGATATCTCATAGTTGCTTTACTTTGCATATTTTAAAATTGTGACTTTCATGGCATAAATAATACTGGTTTATTACAGAAGCACTAGAAAATGCAT DGCDGIEEDKK>LIKHIGMJFHLNJFHLIJAJIIFMMHDIJHGIHIJLIC?LJIEDCA=<3AJIHID)MJGD=@?<8*4JCCA8@928-=92)2@975E)BFE8-;L>CFC>8K?E=8''?@9A>6C694*%;,/44* X0:i:1 X1:i:0 MD:Z:4A25A63C5T0 RG:Z:ERR229776 AM:i:37 NM:i:4 SM:i:37 MQ:i:60 XT:A:U BQ:Z:B@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.70199275 99 17 391 29 101M = 711 374 ATATTTTAAAATTGTGACTTTCATGGCATAAATAATACTGGTTTATTACAGAAGCACTAGAAAATGCATGTGGACAAAAGTTGGGATTAGGAGAGAGAAAT ?EFGGHHFFIEIIEF?C@ABICJICEIJJJLLJJM?H>HHCFI:G>AEHJILLFHGCMJGLKEM>-5A8BKE;JIJHFH4AEIAGMJDF@EHKJHJLHD9JKJN?JLFAG=GMGKKJIAJAJGHI@JGIKKIMHLIIGDILHIF>CGJJLGDC8DHHLGFGFE? X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:FE@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.5711913 163 17 409 60 101M = 646 337 TTTCATGGCATAAATAATACTGGTTTATTACAGAAGCACTAGAAAATGCATGTGGACAAAAGTTGGGATTAGGAGAGAGAAATGAAGACATATGTCCACAC <@CDFD@A?HIIGFJKJLLIFIFCGIFEEDF@KMC?EI=<<GGCDEEFDD7 X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.22701711 163 17 421 29 101M = 699 375 AATAATACTGGTTTATGACAGAAGCACTAGAAAATGCATGTGGACAAAAGTTGGGATTAGGAGAGAGGAATGAAGACATATGTCCACACAAAAACCTGTTC 93:<>>FC'?IHGIKH7KCHCGJFFJHEFCHJJMCLAHJDHKHMGHMLMEF@IBFIHI@DA:HCIGFA83>=0HHEG7 X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:C@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.52216469 163 17 454 60 101M = 693 339 ATGCATGTGGACAAAAGTTGGGATTAGGAGAGAGAAATGAAGACATATGTCCACACAAAAACCTGTTCATTGCAGCTTTCTACCATCACCAAAAATTGCAA @CEEFFBFE:<>:MEMIMED1N?LLQKQD9)@GNLKB@GHGFA;>A>D>;A;H=?B5DIEAFEC>-(7@C8BAD5>7 X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@C@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.82457097 99 17 474 60 101M = 695 321 GGATTAGGAGAGAGAAATGAAGACATATGTCCACACAAAAACCTGTTCATTGCAGCTTTCTACCATCACCAAAAATTGCAAACAACCACACGCCCTTCAAC A?HGGHHFIGHIJFJLLDEJLJKIJIIIGJLMJHIHKMNNNJMNLJJMKKJJMKMMMLLLNJJMKKLKJMKNNNNIKKIIKMJMHGFKGHC?FEHLDFGDB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:CA@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.93698964 99 17 499 60 101M = 735 336 TATGTCCACACAAAAACCTGTTCATTGCAGCTTTCTACCATCACCAAAAATTGCAAACAACCACACGCCCTTCAACTGGGGAACTCATCAACAACAAACTT BFFGHGFHFHEIKKKLIKLIIJLJJKKLJLIMKKMMJKMKKMKKMKNNMNKLLMKNNKKNKMKJKKBKJIOJKKGINHGEGHHGMIJIIJIGJHFIBFDHD X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@CC +ERR229776.17900575 99 17 527 60 101M = 760 333 AGCTTTCTACCATCACCAAAAATTGCAAACAACCACACGCCCTTCAACTGGGGAACTCATCAACAACAAACTTGTGGTTTACCCACACAATGGAAGACCAC BEGKGHGLHFDIIGIIKILLLLIKKLJMLIJKILJIKJBMMMNKLKMKNLMMMJLJMMKKKJLIJMHKMIEMJHJICJFDFHIHJGGGKDIIGJGHIDEFB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.65476258 147 17 548 60 101M = 324 -324 ATTGCAAACAACCACACGCCCTTCAACTGGGGAACTCATCAACAACAAACTTGTGGTTTACCCACACAATGGAAGACCACTTAGCAACAAAAAGGACCAAA BCGGGE@GIAJGDGIHAIGFKNMJKKJKJHKLJGKKJJLKKJJHIKKJJKGJJJKILGGHBHFBHHJIHIGF:KGBJIEJKFFHGAGGHGBBHD;DCEEEA X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@CA +ERR229776.83749675 163 17 553 60 100M1S = 783 330 AAACAACCACACGCCCTTCAACTGGGGAACTCATCAACAACAAACTTGTGGTTTACCCACACAATGGAAGACCACTTAGCAACAAAAAGGACCAAACTCCT ?<:GH:?I59=G@JHHDC3D'6@?ACFHI:E?>;BG=BECFIBH:6?E<6?GDEDHDCHDE65?=GE## X0:i:1 X1:i:0 XC:i:100 MD:Z:100 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B@@ +ERR229776.19017039 99 17 560 60 101M = 839 368 CACACGCCCTTCAACTGGGGAACTCATCAACAACAAACTTGTGGGTTACCCACACAATGGAAGACCACTTAGCAACAAAAAGGACCAAACTCCTGGTACAT ?GDB=1GFFK:GHGH=F?G=CHJJ?DJLGGDGCCC6CIEA?.@E9 X0:i:1 X1:i:0 MD:Z:44T56 RG:Z:ERR229776 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.78639790 147 17 590 60 101M = 335 -355 CAACAAACTTGTGGTTTACCCACACAATGGAAGACCACTTAGCAACAAAAAGGACCAAACTCCTGGTACATGCAACTGACAGATGAATCTCAAACGCATTC CFDGCCHEBGDGFDBKCACBCBC?HKIKDGKLEJJGDHMDG45?IIFIHDEDHIBHA:94'ECEFHC=EH>BFGB@@?:?CEFFFBKJG=JD>EIGFGHHLGBECIKJJ?JLBG=JHGHIIIJMHKKIJGIIC5FGIJGGEIGGFEFIEEHE7 X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@G@ +ERR229776.47649789 147 17 647 60 101M = 392 -355 AACTCCTGGTACATGCAACTGACAGATGAATCTCAAACGCATTCCTCCGTGTGAAAGAAGCCGGACTCACAGGGCAACACACTATCTGACTGTTTCATGGG 68BIAGJE?C?=8JI=5@EIEJHLJJIHGGGBGC?=.?JBAAG=A4EAHJ=FFJJJKJLHH@KJIDHB=HF>?FF>HF@FH;DGI@GAGF7@;@=;3?DBA X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A +ERR229776.52216469 83 17 693 60 101M = 454 -339 CCGTGTGAAAGAAGCCGGACTCACAGGGCAACACACTATCTGACTGTTTCATGGGAAAGTCTGGAAACGGCAACACCATTGAGACAGAAAACAGGTGAGTG C=DHEIHFFLIANGFAKIJLMIILOKJJKLLKKKKNKKMMKLKMKKNNLLKKMMMLLNHKMKMKJJJCKLKJIJILKIMJLLKGJLKFIIGHKFFHFKEHB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D +ERR229776.82457097 147 17 695 60 101M = 474 -321 GTGTGAAAGAAGCCGGACTCACAGGGCAACACACTATCTGACTGTTTCATGGGAAAGTCTGGAAACGGCAACACCATTGAGACAGAAAACAGGTGAGTGGT ?HEFAC>LEAG@C=A@GKKCFHLJJKKJHFCHGKJJJEIGJMJEKFIJJJCHIJKMIFJIFFJJI@FHGH>>;HEEIFCJJ=DJGCGBBEEACFBICEDDB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D +ERR229776.22701711 83 17 699 29 3S98M = 421 -375 TGTGAAAGAAGCCGGACTCCCAGGGCAACACCCTATCCGACTGTTTCCTGGGAAAGTCTGGCAACGGCCACACCATTGAGACAGACAACAGGTGAGTGGTT ####FCGEAFD7::.:DB;'=CB+D@BFFF;2C<,8-%H@C@FI;F-+KIHDCB@57CID<*A4/)G:)ID0IJGKIDIDGEH8<+==FLAEGCKEFEDD? XC:i:98 MD:Z:16A11A5T9A13A6A16A15 RG:Z:ERR229776 AM:i:29 NM:i:7 SM:i:29 MQ:i:29 XT:A:M BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.70199275 147 17 711 29 46S55M = 391 -374 CAGACAAATGAAACTCAAACAAGTTCCCCCGTGTTAAAGAAAACGAACTCACAGGGCAGCACACTATCTGACTGTTTCATGGGAAAGTCTGGAAGCGGAAA ##############################################CC<+2:::)HD@(8<6C?A;?>=>,'7(>@3>6><=<1;+7:8>A4@9%.*<07* XC:i:56 MD:Z:12A35A3C2 RG:Z:ERR229776 AM:i:29 NM:i:3 SM:i:29 MQ:i:29 XT:A:M BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.93698964 147 17 735 60 101M = 499 -336 ACTGTTTCATGGGAAAGTCTGGAAACGGCAACACCATTGAGACAGAAAACAGGTGAGTGGTTGCCTGGGGCCAGGGAACTTTCTGGGGTCATACTCTCTAT AEHFGJG:@GHHIHFI@;>JHHEEH@IJJCKJFJJKMJJIIJJHIJGI=HFHGJKLIEFFKICDIDKBIKE@IIIJHGIKKHIGIDIFIG<IFKMJMBGKDFFJF@CGBBIGINHJEJI?FFBDILDLDDILIFGA7)?EEHLIMIHFIFHHHIFDFJD X0:i:1 X1:i:0 MD:Z:83T5G11 RG:Z:ERR229776 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@F +ERR229776.92236775 81 17 758 37 101M * 0 0 AACGGCAACACCATTGAGACAGAAAACAGGTGAGTGGTTGCCTGGGGCCAGGGAACTTTCTGGGGTCATACTCTCTATGTTGATTCTGGTGGTGGAAACAA A?>FGG@BDCFFJIJIMIKIMFFIKJILIIKJNIKJILJMJKKMLMLMLMJIIJFINMLFJGLKJKJJHIKKJLJHIJJLIIHDJKIJGIEFGFGHGHDFB X0:i:1 X1:i:0 MD:Z:70T5G24 RG:Z:ERR229776 AM:i:37 NM:i:2 SM:i:37 XT:A:U BQ:Z:CA@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@AA +ERR229776.17900575 147 17 760 60 101M = 527 -333 CGGCAACACCATTGAGACAGAAAACAGGTGAGTGGTTGCCTGGGGCCAGGGAACTTTCTGGGGTCATACTCTCTATGTTGATTCTGGTGGTGGAAACAAGA +EGGCFD>EEFAJIIIJHMHEEJJHKIHJIMDCHHKKJJJJMMEEEKMKIBHBLKLKCIJKLIJGHCAGIFDDF>HFHFIHECEGDF?GEB?EFCFEEIEB X0:i:1 X1:i:0 MD:Z:68T5G26 RG:Z:ERR229776 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.83749675 83 17 783 60 101M = 553 -330 ACAGGTGAGTGGTTGCCTGGGGCCAGGGAACTTTCTGGGGTCATACTCTCTATGTTGATTCTGGTGGTGGAAACAAGACTGTCCCAGCCTGGGTGATACAG EEICDIHLCGFDCHH>DFHFKGDCNEKJJLHLLG;KIIIDLJEEJD@IC=D=0GMFLIJLCJHHCHFEHIIHHJHIHDFIHKHGHKH>HHAFDE=GEF=H: X0:i:1 X1:i:0 MD:Z:45T5G49 RG:Z:ERR229776 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.63559677 147 17 833 60 101M = 594 -339 TATGTTGATTCTGGTGGTGGAAACAAGACTGTCCCAGCCTGGGTGATACAGCGAGACCCCATCTCTACCAAAAAATTAAAAATTAGCTGGGCATGGTGGTG FDHFHIHEF@FDD;5AC::ELBGCBHE3DKIHEHMFAHLE=BACIGH>IFB7FEHBC=G>KHFCHIFFGJDHEFFBB@BACFCCD@ X0:i:1 X1:i:0 MD:Z:1G99 RG:Z:ERR229776 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:[YZA@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.19017039 147 17 839 60 11S90M = 560 -368 CTCTCTATGTTGATTCTGGTGGTGGAAACAAGACTGTCCCAGCCTGGGTGATACAGCGAGACCCCATCTCTACCAAAAAATTAAAAATTAGCTGGGCATGG ############GJE:GEE?9)D<=B?09>.>/1?ACBCBIJIA@@?5FEEC9HL<<8?7,B?@@@BGHGC9BHIHGI:GG@BHHCFGGJ<3ED;;CDAB@ X0:i:1 X1:i:0 XC:i:90 MD:Z:90 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.98760722 163 17 840 60 101M = 1103 363 ATTCTGGTGGTGGAAACAAGACTGTCCCAGCCTGGGTGATACAGCGAGACCCCATCTCTACCAAAAAATTAAAAATTAGCTGGGCATGGTGGTGCATGCCT CBG@;DACF=HDJFJJCMJH@JGIKKIFDFFFHHEGEDHKHGCGJJICAB=?AIIIGGEG X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C +ERR229776.516742 163 17 845 60 101M = 1152 407 GGTGGTGGAAACAAGACTGTCCCAGCCTGGGTGATACAGCGAGACCCCATCTCTACCAAAAAATTAAAAATTAGCTGGGCATGGTGGTGCATGCCTGTAGT A;>HF=GAIHGGH?FIEHGE9EFCIEA=@@ X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@CBFH +ERR229776.55719080 99 17 994 60 101M = 1282 388 TCAAGGCTGCAATGAGCTATGATTGCGCCACTGCACTTTGGCCTGGACAACAGAGCAAAACCCTGTCTCTAAAAAAAGAAAAGAAAAGAAAAACTCACTGG BFHIGFHLHHEKIIJKKKHIJKIKILAKLJJLJKJJMKKLJLMMJMLKKNKKMLKLKNNNKMMMKIKMJNKMMMNGHHJFHHIKHIIIKHIHCGMGHDIEC X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A +ERR229776.77830097 163 17 1036 60 101M = 1255 319 CTGGACAACAGAGCAAAACCCTGTCTCTAAAAAAAGAAAAGAAAAGAAAAACTCACTGGATATGAATGATACAGGTTGAGGATCCATTATCTGAAATGCTT BIEBGCCHCBCHHH,=FICDJKHCGDGJHJJKHFIIJKLLIKLGLGKLMMDHLJJDLFIKIDIDIKIGJIFHHGFHEHJH?JIIFJFFIIFLIJHGHGGIB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D@ +ERR229776.3695912 99 17 1042 60 101M = 1118 176 AACAGAGCAAAACCCTGTCTCTAAAAAAAGAAAAGAAAAGAAAAACTCACTGGATATGAATGATACAGGTTGAGGATCCATTATCTGAAATGCTTGGACCA BHEGGIHHHKIKGJKLJIKLLLIMMMMMMJKLMMKLMMNKLNMNNKLLJJNLMLKJKJLMKJLJJHKJHHHHLHFJIHHHIKIKINJKIHJIIMJGEHDED X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@C@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.54641833 99 17 1042 60 101M = 1321 379 AACAGAGCAAAACCCTGTCTCTAAAAAAAGAAAAGAAAAGAAAAACTCACTGGATATGAATGATACAGGTTGAGGATCCATTATCTGAAATGCTTGGACCA BHEGGIGGGKIKGGKKHAHLJLIMMMMMLJKLMMKKMMMFLLMNMJNMKJMJMLKJKJLMKJLJJHKJHGHHJHFJIJHHIKIKINJKIHJIIMJGEHDEF X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR229776 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@C@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B +ERR229776.90795085 163 17 1066 60 101M = 1297 331 AAAAAGAAAAGAAAAGAAAAACTCACTGGATATGAATGATACAGGTTGAGGATCCATTATCTGAAATGCTTGGACCAGATGTTTTGAATTTTGGATTTTTT BGHGHEDHGDCHJGJHIJI?JGJIHHKIKIGHHIKLIFKIIJIHL=HIKJCIGLLHIHKJMLKIEBEHJMLJDMIJKJMIKLDHKCJJGFDHHGGGEFFCB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:JOOLJ@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@BCEGEE +ERR229776.51118640 99 17 1069 60 101M = 1370 401 AAGAAAAGAAAAGAAAAACTCACTGGATATGAATGATACAGGTTGAGGATCCATTATCTGAAATGCTTGGACCAGATGTTTTGAATTTTGGATTTTTTCAT BHFHIJJHJKIKJJKKLKHLLJJMKLKJJJKLMJKLJJJKMMFJGKKMLJMMKKLJKMNLMNNKLMNKLKLKMKLMLLIGLLIKNKKLKJCKHFEEFCFGE X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:EJ@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B +ERR229776.57580585 163 17 1077 60 101M = 1316 339 AAAAGAAAAACTCACTGGATATGAATGATACAGGTTGAGGATCCATTATCTGAAATGCTTGGACCAGATGTTTTGAATTTTGGATTTTTTCATATTTTGTA BGHGEEE@G>9JHEGHGIFFHHHJKHHIFBAIIFGHHIJKHIJKIIKJIKGJKMLJKKNKKBLDLJKLJLKKJKHLIKLKLKIKLFLKLFIJJEIJGHFDE X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:CFFB@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@G +ERR229776.82642257 163 17 1081 60 101M = 1336 355 GAAAAACTCACTGGATATGAATGATACAGGTTGAGGATCCATTATCTGAAATGCTTGGACCAGATGTTTTGAATTTTGGATTTTTTCATATTTTGTAATCT BGHGHH@JEB@JGHHEGGGHJHBJHHIFIICIA>HDJIKJIIJIILLKJLGJJLMJJGLJLGKIHJ=JJKLLMJKKLKFMKLLLLFIJKIKKKKHGGFGGJ X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@L +ERR229776.30538656 163 17 1087 60 101M = 1321 334 CTCACTGTATATGAATGATACAGGTTGAGGATCCATTATCTGAAATGCTTGGACCAGATGTTTTGAATTTTGGATTTTTTCATATTTTGTAATCTTTGCAG A?BHJEKFGG??IKKKAEIKJJLLKLLEHKLKIHIJIILEGGEG? X0:i:1 X1:i:0 MD:Z:7G93 RG:Z:ERR999999 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.87113255 99 17 1096 60 101M = 1361 365 TATGAATGATACAGGTTGAGGATCCATTATCTGAAATGCTTGGACCAGATGTTTTGAATTTTGGATTTTTTCATATTTTGTAATCTTTGCAGTATATTTAC ?EFGGFHHJHFGIAHIIFKLLKJKLJJKIJKMKLMMJJMNKJMEHHFIEDIKLKLGLLKLLLLKLKJHKJJKKHKFIKD;JCGEIGDIIDK=4CEDEFAEB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D +ERR229776.98760722 83 17 1103 60 101M = 840 -363 GATACAGGTTGAGGATCCATTATCTGGAATGCTTGGACCAGATGTTTTGAATTTTGGATTTTTTCATATTTTGTAATCTTTGCAGTATATTTACCAGTTCA EFFFGLHGHJLNKLKJGLLNLILLLIAKKKJLNKJHJMJNIJKDNNNKLLKNNNJMMJMNNNNLKJIJMMMJIJKJKLMLJJEFHHHCIJAGFFHLDIHE? X0:i:1 X1:i:0 MD:Z:26A74 RG:Z:ERR999999 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.37017046 99 17 1113 60 101M = 1339 326 GAGGATCCATTATCTGAAATGCTTGGACCAGATGTTTTGAATTTTGGATTTTTTCATATTTTGTAATCTTTGCAGTATATTTACCAGTTCAGCATCCCTAA BHDCIGGFIGCGIGKJKIKIJKLIKLKILJKKJFHJKKILJJKKLLMHJJKKLLMIJJKLLLJKJMKMNLLIJKLKKLDFLLKAFHDIIIJHKLGGFFJED X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B +ERR229776.3695912 147 17 1118 60 101M = 1042 -176 TCCATTATCTGAAATGCTTGGACCAGATGTTTTGAATTTTGGATTTTTTCATATTTTGTAATCTTTGCAGTATATTTACCAGTTCAGCATCCCTAACTCAA GDFGGHIJILLFHHMIIMLJKLIJNKKKIMNNKKKKMKMILMJLMMMMLIEIJMLJJIIJIKKLLIKIKIBGHHKJHGEIKFIIHHIGGHBAEFCDEEEE@ X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:B@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@GE +ERR229776.17531023 163 17 1121 60 101M = 1381 360 ATTATCTGAAATGCTTGGACCAGATGTTTTGAATTTTGGATTTTTTCATATTTTGTAATCTTTGCAGTATATTTACCAGTTCAGCATCCCTAACTCAAAAA BEEEDE@EFDEFGFI>GBCBJHFGGIBGFFEJIFJJJJKEFJJJJJKJIHEJKKIEGHJMMKKHGJHFIKJIKKJHJKKKIHJKKLJKHILGMGMHHIEEE X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@CGDFG +ERR229776.516742 83 17 1152 60 101M = 845 -407 AATTTTGGATTTTTTCATATTTTGTAATCTTTGCAGTATATTTACCAGTTCAGCATCCCTAACTCAAAAATTAAAAAATCTGAAATCCCAAACGCGCCAAT 7?ABDGED>DDDDJE?FB9DDCEA.=<>AD=/AEG6ABA8FD>2CGF@GFBJ?>5*G>59@.<*4JKIB;D*)JJIIBHA:8GC>=E4;H7C>F?GCEDE? X0:i:1 X1:i:0 MD:Z:72C28 RG:Z:ERR999999 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.36576640 83 17 1160 60 101M = 937 -323 ATTTTTTCATATTTTGTAATCTTTGCAGTATATTTACCAGTTCAGCATCCCTAACTCAAAAATTCAAAAATCTGAAATCCCAAACGCGCCAATAAGCATTC ADEFFKKIJIIHIIJGJIHIIFKJJINIHJJJMLHGHJLIMHGLJIGEFJKGFDKGCLKLLKMLHKKKKJLJGIKJIKLKJJIGBKAJHIGHHHLHGGHGB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D +ERR229776.6073289 83 17 1160 60 101M = 857 -403 ATTTTTTCATATTTTGTAATCTTTGCAGTATATTTACCAGTTCAGCATCCCTAACTCAAAAATTCAAAAATCTGAAATCCCAAACGCGCCAATAAGCATTC <@AFFKKIJIJHIIJGIIJJHFHKJHNIJKJHBEF@HGKHMLJLJJJLMJKIJGKGHLKLKJLLHKKKJIKJJLKJIKLKJJIGBKAFEIEHGHLHGGHHB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D +ERR229776.78971137 163 17 1189 60 101M = 1464 375 ATATTTACCAGTTCAGCATCCCTAACTCAAAAATTCAAAAATCTGAAATCCCAAACGCGCCAATAAGCATTCCCTTTGAGCGTCATGTCGGTGCTTGGAAT BBFEFFBCCB@GHHGHHGDHJJJHIGKIHGJLJHJJILLLLILJGKLMIKDFHLKHAE;@HGMGILHFIJIIFGLJJHBCHAGEGIIKIAG>CEMEGEHHD X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A +ERR229776.87728427 99 17 1242 60 101M = 1483 341 AACGCGCCAATAAGCATTCCCTTTGAGCGTCATGTCGGTGCTTGGAATGTTTGGGGTTTTGGATTTACAGCTTTGGGACGCTCAACCTGTACCTCAATAAA BHE>G?HFHKGIKKKIIIKKLLJKKKHKCEJJJJEJ?JEBDMJJMABJJIJKLJJJFCDCGDHGCCHEHGHLEEHFGHC;IMIJHGINIIIGIMHIIGGD@ X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:DJ@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@BB@ +ERR229776.77830097 83 17 1255 60 101M = 1036 -319 GCATTCCCTTTGAGCGTCATGTCGGTGCTTGGAATGTTTGGGGTTTTGGATTTACAGCTTTGGGACGCTCAACCTGTACCTCAATAAACCTGATTTTAAAA EEFFIFFIHHGINJAGKIJJGHAIJGKKMKJLKKKINMJMMLKNNNKMMKNMJJLNMMMNKMHJEALKKFJJJLJJIIILKJJHIIIEHIFHHJJJGGFFB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@IKMJ +ERR229776.55719080 147 17 1282 60 101M = 994 -388 CTTGGAATGTTTGGGGTTTTGGATTTACAGCTTTGGGACGCTCAACCTGTACCTCAATAAACCTGATTTTAAAAAAGTTTGGGGGCATTCCCCTAAGCCCG ?EIHGEHF@HCJHEFEIHEGGGHIGHHHKG>BGJDEFDBGJKDCEJKJHJELJJIJIGHF@KKIKILKKHHHIIIKGJJHJHEFDGLJJMJLLKIIJLMLJMJJMNKLLJLKLKLJNNNNKKHKKLJJJHDHGDGJGGLHGHJIHAGHJGIHAGKIHGJII@FFCCCE X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@G +ERR229776.57580585 83 17 1316 60 101M = 1077 -339 GGGACGCTCAACCTGTACCTCAATAAACCTGATTTTAAAAAAGTTTGGGGGGATTCCCCTAAGCCCGCCACCCGGAGACAGCGGATTTCCTTAGTTACTTA BEDG?HHKHIJGIKHFHGHKFDIJE?HFHIGJFFFFCCCCCKDEEGFFFFFFFEHDDDFFCJEJLCJIHGLLCLLMKIILK@KKHLKJHIIHKFJHHGHFB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:AC@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.30538656 83 17 1321 60 101M = 1087 -334 GCTCAACCTGTACCTCAATAAACCTGATTTTAAAAAAGTTTGGGGGGATTCCCCTAAGCCCGCCACCCGGAGACAGCGGATTTCCTTAGTTACTTACTATG EEHFDIFIJHIHFFCIFIIIFDGIKJJGGGGDDDDCJDECGEDEFFGECGDDDFGBCACJBGIIEJLCLKMIJKLLBLIILLKKIKHKGKFGIEGDGEFI? X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.54641833 147 17 1321 60 101M = 1042 -379 GCTCAACCTGTACCTCAATAAACCTGATTTTAAAAAAGTTTGGGGGGATTCCCCTAAGCCCGCCACCCGGAGACAGCGGATTTCCTTAGTTACTTACTATG FFHGEHEIJDFGBHKIHHGC<4FHIHHFFFF?BDBEI>G>GDCADCDDDI>AAEE@GAAD>FEB@HG8EGHIIIKHAJIHKEFGHEGGEHB;E@BDEEED@ X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.29727862 163 17 1327 60 35M66S = 1641 363 CCTGTACCTCAATAAACCTGATTTTAAAAAAGTTTGGGGGGATTCCCCTAAGCCCGCCACCGGGAGACAGCGGATTTCCTTAGTTACTTACTATGCTCCTT 7==;A97.8+7HA;IE:88;9EEFH8>;?E####################################################################### X0:i:1 X1:i:0 XC:i:35 MD:Z:35 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.82642257 83 17 1336 60 101M = 1081 -355 CAATAAACCTGATTTTAAAAAAGTTTGGGGGGATTCCCCTAAGCCCGCCACCCGGAGACAGCGGATTTCCTTAGTTACTTACTATGCTCCTTGGCCATTTC DBEFFGGGIJIKIIIIFFFFFKFHHGHGGGGHD?HEDDFFCKGDGBMJIFJC@MLNMKJLLBMMJMMLLMMJMJLIJLLIILIGIJKJHIIHGHFHGDEGA X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.37017046 147 17 1339 60 101M = 1113 -326 TAAACCTGATTTTAAAAAAGTTTGGGGGGATCCCCCTAAGCCCGCCACCCGGAGACAGCGGATTTCCTTAGTTACTTACTATGCTCCTTGGCCATTTCTCT :DCCDCJFIJHHF9FFHHMFGCFGGEDEC94#455D@=I?7BADBJJIJBCHMJJDMH?HGDLKJAHEHKA@>B=HDBIGHAEHH8ADDF<8DFEHGEGB@ X0:i:1 X1:i:0 MD:Z:31T69 RG:Z:ERR999999 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.87113255 147 17 1361 60 101M = 1096 -365 TGGGGGGATTCCCCTAAGCCCGCCCCCCGGAGACAGCGGATTTCCTTAGTTACTTACTATGCTCCTTGGCCATTTCTCTAGGTATTGGTATATTGTGTATG FEFFGGHDCHCC;HIF?15;7A:4#FD>JKG@DGMKBFLFKLKAJ@AMEE9BEBB:GFB?CIEHGJA<>DDH=BJEJIBFGJAF:DGDMIIMJJCKLLILLILKHIHKKKIJKHHFDFHKHIGHHFFJGEGFIHBBEF@FEEGDB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.48996859 99 17 1381 60 98M3S = 1659 345 CGCCACCCGGAGACAGCGGATTTCCTTAGTTACTTACTATGCTCCTTGGCCATTTCTCTAGGTATTGGTATATTGTGTCTGCTGTGAACTGTCCTTGGCCT A5FEFEGF?EHHIEIIH8HIIJJIHLJIHGIJHMJJJNA:FAIHGML;0GEDGILGHKHGKHHIKINJKLIJGGFFFF8FFLJJIFEGHLKJGGKMLILLLJKKILKIIILEKHFJJIGEE? X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C@ +ERR229776.87728427 147 17 1483 60 101M = 1242 -341 TTTGGTGACGGGTGAGGAGCAGGGACAGAAGGGTCCTGCGTGCCCTGCCTTCACAAGCCCCTGGAAGGAAAGTTGTTTTGGGATCTCTGCACCCTCAGCCT :=;FCD?1/EECJIGHCF>AAFGCIHKEA=BDAF<:EB>JFJIDBHHCHAD>+#AFDEIE?B@ X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.15144424 163 17 1542 60 101M = 1799 357 CCTGGAAGGAAAGTTGTTTTGGGATCTCTGCACCCTCAGCCTGGACAACTTGTGCCCATCTGGTGACCCCTCACTCAGCCACCAGACTTCCACGACAGGCT BDIECGEFDCEIHBGCGHGGGJEGHBIFHDJIGHJKJIJJKLH?K@JKFJEJIHILMFJMMHB;>IHIIIMIJCKKIFJHGFHJDHGMFIIJG>JFHBDDF X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:EF@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A +ERR229776.83025798 147 17 1590 60 101M = 1304 -386 CTTGTGCCCATCTGGTGACCCCTCACCCAGCCACCAGACTTCCACGACAGGCTCCAGCCTCGGCACCTTCAGCCATGGACAGTTCCGCCAGCGTTGCCCTC CA;4I?C?9HGCJEBD<08@2J<+=@=DB9CD@ X0:i:1 X1:i:0 MD:Z:26T74 RG:Z:ERR999999 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.29727862 83 17 1641 60 51S50M = 1327 -363 CTTGTGCCCATCTGGTGACCCCTCGCTCAGCCCCCAGACTTCCACGACAGGCTCCAGCCTCGGCACCTTCAGCCATGGACAGTTCCGCCAGCGTTGCCCTC ####################################################E==>=55;,C:65/9:=5J=C>FF@=GBJCB?5"D1?L;1=EHG;=BA0 X0:i:1 X1:i:0 XC:i:50 MD:Z:50 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.107364540 99 17 1651 29 101M = 1920 369 GGCACCTTCAGCCACGGACAGTTCCGCCAGCGTTGCCCTCTGTTCTGCTGTTTTCTCTACCAGAAGTGCCCTTCCCTCCTCACCTGACCACTCTGGGGAAA ?CGGDFL?FHCGFFIAKJIIJGIEHALLJJKGCHGEIEELFIFHMGFGIJDFMFKGIJCMEKHFEAHDF X0:i:1 X1:i:0 MD:Z:14T86 RG:Z:ERR999999 AM:i:29 NM:i:1 SM:i:29 MQ:i:29 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@CBF +ERR229776.48996859 147 17 1659 60 33S68M = 1381 -345 GACTTCCCCGACAGCCCCCAGCCTCGGCACCTTCAGCCACGGACAGTTCCGCCGGCGTTGCCCACTGTTCTGCTGTTTTCTCTACCAGAAGTGCCCTTCCC ##################################G=:?F3CCE>D:8=64'#)'I<=):7>HIB@=A:CE1;:C=JJHC9A:<7=BCFHCL@LHEHIEHA@ X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.69874320 163 17 1704 60 81M20S = 1920 309 TCTCTACCAGAAGTGCCCTTCCCTCCTCACCTTACCACTCTGGGGAAATCCCTCAGCACCCTCCCTGAGCATACCCTACTCCGGCACAAGCCCAACCTGCA 74J?@C:D@-=C;696/*=;DD8+@*@7C94='04*65:A@860;+9H##################### X0:i:1 X1:i:0 XC:i:81 MD:Z:32G48 RG:Z:ERR999999 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.51562629 147 17 1727 60 101M = 1445 -382 TCCTCACCTGACCACTCTGGGGAAATCCCTCAGCACCCTCCCTGAGCATACCCTACTCTGGCACAAGCCCACCCTGCAAAGCCCCTGAGGCCCGCCCTGTG ADDFD?GHHEBGIGIHIJHHHHGGHGFEGHFJB;2CB?FADDEAJDDFC@8ABCE?A@BCACCB@H@<AEGG@HEG;ACBGCHFFAFF/?GFJLHILKLHIGGIJM:CECFEIHLBFIDJEHEHILAHB5CFG@FGGLHHHGI3?FFILIHHMHGGKC6C X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:GAA@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.2494821 99 17 1749 60 101M = 2024 375 AAATCCCTCAGCACCCTCCCTGAGCATACCCTACTCTGGCACAAGCCCACCCTGCAAAGCCCCTGAGGCCCGCCCTGTGGCGTCTCTCCCTCCCTTGCTGT AHHGFFFLHHGIIHKKHHJKLJKLKJJJJLLMJJJJMJCLJJJNFJLMKKMMNLMKLNMMLMIMHKJHJGG@ X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@FC@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.15144424 83 17 1799 60 101M = 1542 -357 CCTGCAAAGCCCCTGAGGCCCGCCCTGTGGCGTCTCTCCCTCCCTTGCTGTCAGGACAGTGGTCCTGGCCTCCGGGGCTCACGGAGCCGCCCTGTGCCATG @BGGGGB8D@HEHKEJFGGGACGCGKFGGF?EGCCCCDDCGEEFEIGFHDIFJEGGFJDFEBHCEFGEGJKE>LLLKJKII@KKLKKAIHFIHFHHEGFHB X0:i:1 X1:i:0 MD:Z:70A27G2 RG:Z:ERR999999 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:BD@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@Z\V +ERR229776.97978507 163 17 1893 60 101M = 2135 342 TGCCGTGTACCTCTGAGCCCTCTGCACAGTGCCTTCTGCTTGCCTGTGGCTTTGAGAAGAAACCCCTTCTGGTTATACATAAGACAGCCAGAGAAGGGAGT BEFCHHGIEFJDFKHGBGCFF7CAD X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D +ERR229776.107364540 147 17 1920 29 101M = 1651 -369 AGTGCCTTCTGCTTGCCTGCGGCTTTGACAAGAACCCGCTTCTGGTTATACATAAGACAGCCAGAGTAGGTAGTTGCCCAGGGTGGCACACTACGTTGCTG <@DE96DJHGG>8CG@:?4$=@*IBB@41AEC<=3+#(B<@6F=287JIG?C8(A@BCIH>MLJFH?C;CJIFGCGDIBIJHDCJCEFFHHIHD?ALEC5CHMD38CECLGCE?45HLCE;BEGFHGJ<=C? X0:i:1 X1:i:0 XC:i:94 MD:Z:94 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.43533499 83 17 1932 60 101M = 1693 -339 TTGCCTGTGGCTTTGAGAAGAAACCCCTTCTGGTTATACATAAGACAGCCAGAGAAGGGAGTTGCCCAGGGTGGCACAGCACGTTGCTGCCAGTTACTGCC 2D>ADFGGIIHFIKILIFLDB51FCBHGGCKJILFIKKJKKJMIHJMLKJMLMJHLIGIMJMKJGJHGKKIJHFIIFLDHG@HIFIGGGH?KCEGHGGF?? X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.22929983 83 17 1950 60 101M = 1693 -357 AGAAACCCCTTCTGGTTATACATAAGACAGCCAGAGAAGGGAGTTGCCCAGGGTGGCACAGCACGTTGCTGCCAGTTACTGCCATTTTCACAGGCATGAAA HEA>CFFGIHKIKIGMKLKJIFKKMEIKLJHKNKMKKNMMLNKNKMJCLMMMJJMMLJKMLHIAKMJLLJKLKMJLJILJJKHHLLKJIIFKGHHHGFFFB X0:i:1 X1:i:0 MD:Z:91G9 RG:Z:ERR999999 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:C@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ADB +ERR229776.66105707 83 17 1971 60 101M = 1746 -325 ATAAGACAGCCAGAGAAGGGAGTTGCCCAGGGTGGCACAGCACGTTGCTGCCAGTTACTGCCATTTTCACAGGCATGAAATGGAGATAACAACAGGAGCGA EFCIGFCMICINIMIGJIKKNBJKIHIKMJJKKLJIFINLJKCKMKLMKJJGMJMIGKJHFHIMMLKJIIMLKJIIKKJIIKKKKHHDIIGIHLFGKF:FB X0:i:1 X1:i:0 MD:Z:70G30 RG:Z:ERR999999 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.105154648 163 17 1981 60 101M = 2189 308 CAGAGAAGGGAGTTGCCCAGGGTGGCACAGCACGTTGCTGCCAGTTACTGCCATTTTCACAGGCATGAAATGGAGATAACAACAGGAGCGACCGCACAGGC @DCE:EEFD<=H?>>?FF==CCB@1:C=FFGHG;<=?HKICHBC?4AFEE:HEC5AJ3B;H?A>6BCEB85 X0:i:1 X1:i:0 MD:Z:60G40 RG:Z:ERR999999 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.52172354 163 17 1982 60 79M22S = 2196 314 AGAGAAGGGAGTTGCCCAGGGTGGCACAGCACGTTGCTGCCAGTTACTGCCATTTTCACAGGCATGAAATGGAGATAAGAACAGGAGCGACCGCACAGGCT A@?:E>31<61E<;88BG,%/C8/4BAG4;BA1AG92D;D?C9<=)?>;C?BDF+9D+0>>0;DGJG####################### X0:i:1 X1:i:0 XC:i:79 MD:Z:59G18C0 RG:Z:ERR999999 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.39805220 163 17 2022 60 82M19S = 2315 385 CAGTTACTGCCATTTTCACAGGCATGAAATGGAGATAACAACAGGAGCGACCGCACAGGCTGCTGAGCGCGTCACACGCAGCCATCGCGCAGCTCAGGGAT @94EAE@J>:3GGEGCGD9=ECACGGHHHE;HHB?DFC1E:AA@AJJE=@C6=43>@CI?8DBC#################### X0:i:1 X1:i:0 XC:i:82 MD:Z:19G62 RG:Z:ERR999999 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.57143597 163 17 2024 60 101M = 2298 374 GTTACTGCCATTTTCACAGGCATGAAATGGAGATAACAACAGGAGCGACCGCACAGGCTGCTGAGCGCGTCACACGCAGCCATCGCGCAGCTCAGGGATAT @DAECIBEC@AGHEICGGIHJHGIEHAGHEDGICFLHILJCJ8FDE>KDD3;C?CJEDHFGEGFCF=F<>>EBIE@DECD?>DB9BECBHCJDADD;AE@;>C>HLEFCDH>IILJ@G6IJGG:AEJACCEEB@ X0:i:1 X1:i:0 MD:Z:17G83 RG:Z:ERR999999 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B +ERR229776.11251161 163 17 2065 60 101M = 2333 368 GGAGCGACCGCGCAGGCTGCTGAGCGCGTCACACGCAGCCATCGCGCAGCTCAGGGATATTACGTGTAACTCGACATGTCAGCGATTGTCACAGGCACTGC @3B"2=<"5?9=JGBBB'=:@;DFC=?698AFCD4;74C@EBD7IBFHH8AD@G+-3HGHFHF>IIKJKIHKBKBLJLLLLJLLJKJJJKJJCHJKJLHMMBLHJJIGIJGI>HFCFGJKEHGFHIFMIJMIDMIIMIHGHADFFIHKIGHEDB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D +ERR229776.18301321 163 17 2092 60 101M = 2301 307 GTCACACGCAGCCATCGCGCAGCTCAGGGATATTACGTGTAACTCGACATGTCAGCGATTGTCACAGGCACTGCTACTCCTGGGGTTTTCCATCAAACCCT AFEECE789<',AD@GF@BG?>H<4F7GBIE=@>FCF;=;CEBFE>D=A=AAJGHKH;DDFKHG?C02BAIHG@@FEAA3=6 X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.97978507 83 17 2135 60 101M = 1893 -342 TCGACATGTCAGCGATTGTCACAGGCACTGCTACTCCTGGGGTTTTCCATCAAACCCTCAAGAGCTGGGCCTGGGGTCAACTTCCAGCCTGGGGAAACTGG E=FGGHIGKINJBIJIJGMIJFMIJHIHJHHIGJLHJJIILFNNNLMLKLJKJGMMMLKKMLMKKJLLLLLJLLLJKKJILLKKJLKJJIEGGGHHHGHEB X0:i:1 X1:i:0 MD:Z:85G15 RG:Z:ERR999999 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@GG +ERR229776.15256528 147 17 2147 60 2S99M = 1898 -347 AGCGATTGTCACAGGCACTGCTGCTCCTGGGGTTTTCCATCAAACCCTCAAGAGCTGGGCCTGGGGTCAACTTCCAGCCTGGGGAAACTGGGGCAAGTATC ###E?E<9G=8IMIIFGED<9;(BABBB;8;99?ABIGDCHJD?<:;C7FBEE3EBHDG9@CCKGHH@??D@;HFG>1EEF=BCDAG9631,D9DE@7 X0:i:1 X1:i:0 XC:i:99 MD:Z:20A52G25 RG:Z:ERR999999 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.75821297 145 17 2155 37 101M * 0 0 ACAGGCACTGCTACTCCTGGGGTTTTCCATCAAACCCTCAAGAGCTGGGCCTGGGGTCAACTTCCAGCCTGGGGAAACTGGGGCAAGTATCACCAGAGATG EFKFHHIIJIIH@IKGIJHHHFLLLJFGJKHJHEIIMJJKMLNKKIKKMJGELKLJKGHGLLKIJLKJKIJIKKIHHJFJJHHHHHGFGH<;DEFEIEEG@ X0:i:1 X1:i:0 MD:Z:65G35 RG:Z:ERR999999 AM:i:37 NM:i:1 SM:i:37 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.105154648 83 17 2189 60 101M = 1981 -308 CCCTCAAGAGCTGGGCCTGGGGTCAACTTCCAGCCTGGGGAAACTGGGGCAAGTATCACCAGAGATGAGCTTTATAAAAATAATGGTGCTAGCTGGGCATG ?BEHFGKILIHGFFGDFGEGFBHEGKHNLFJNLKKKLILKKIKKKLIFJCKJJJJLJKJJMLMJIIJJICLLJJIIJIIEHJGGJHIFHIIHDHFFFEFH? X0:i:1 X1:i:0 MD:Z:31G69 RG:Z:ERR999999 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A +ERR229776.52172354 83 17 2196 60 101M = 1982 -314 GAGCTGGGCCTGGGGTCAACTTCCAGCCTGGGGAAACTGGGGCAAGTATCACCAGAGATGAGCTTTATAAAAATAATGGTGCTAGCTGGGCATGGTGGCTT EHCBDDB?7=E=DBAKCDGLHHEIMICHKJHAKKKK>CDJIJIKMGFJKIFFJMLMHIIEMJKMDHIJKJKJJJIIJKIJJJHJHFHGFIJGADHICGHJIJKDIIFIJCGEDGBD X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:EJ@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@F +ERR229776.59500924 99 17 2276 60 101M = 2490 314 GCTAGCTGGGCATGGTGGCTTGCACCTGTAATCCCAGCACTTTGGGAGGCCGAGCTAGGAGGATCGTTTGAGTCCAGCAGTTTGAGACCAGCCTGGCCAAT &HIEGHLHGHFIHEKIHKJLJILJJLLKIIMJLLLJMJIHMKKJJMGFJJLCLIJNJKJLJGHGJ>G@@GJGHIHKHJJFIFKIKIKGIJIIIMHAEFGDD X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.57143597 83 17 2298 60 101M = 2024 -374 CACCTGTAATCCCAGCACTTTGGGAGGCCGAGCTAGGAGGATCGTTTGAGTCCAGCAGTTTGAGACCAGCCTGGCCAATACGGCAAAACCCAGTCTCTACA ?EDFHFHFHHHEFJJFIHDEJFHHMEIF@KOJJJNJKMJMKL?JNMKLNKLMLMJJMJMMKJLCBLJILJLJLKIIKJII@JJF?JIFHEFKFJHIGGGFB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D +ERR229776.18301321 83 17 2301 60 2S99M = 2092 -307 ACCTGTAATCCCAGCCCTTTGGGAGGCCGAGCTAGGAGGATCGTTTGAGTCCAGCAGTTTGAGCCCAGCCTGGCCAATACGGCAAAACCCAGTCTCTACAA ###GAB7.BC><:*5'=GG@A:?H@A8,@B77FE-EIEEEHBDBKJDH=IACICBGGLLJHH'%/HLJCHICICFADHA?E?>:B?I:FG=EI:@@=ADC? X0:i:1 X1:i:0 XC:i:99 MD:Z:13A47A37 RG:Z:ERR999999 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ED +ERR229776.39805220 83 17 2315 60 8S93M = 2022 -385 TCCCAGCACTTTGGGAGGCCGAGCTAGGAGGATCGTTTGAGTCCAGCAGTTTGAGACCAGCCTGGCCAATACGGCAAAACCCAGTCTCTACAAAAAATACA #########DFBIFEJB?%?I@FFIMFFGFFFD;DLMJEJ>8FGMHGHBMKHFM=/GCJFJKEKJCFJD8JAHHIJJIIIDII@AEJFGHBGHHHHFEHC? X0:i:1 X1:i:0 XC:i:93 MD:Z:93 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A +ERR229776.12020490 147 17 2330 60 101M = 2089 -341 CTAGGAGGATCGTTTGAGTCCAGCAGTTTGAGACCAGCCTGGCCAATACGGCAAAACCCAGTCTCTACAAAAAATACAAAAAACAACTAGCCAGGCGTGGT EFKFGLHIEHGFHIIDDHHCIAJGBBHDB;=+EB@ X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.11251161 83 17 2333 60 101M = 2065 -368 GGAGGATCGTTTGAGTCCAGCAGTTTGAGACCAGCCTGGCCAATACGGCAAAACCCAGTCTCTACAAAAAATACAAAAAACAACTAGCCAGGCGTGGTGGT BA,>9DHC@BEKKIKCAAGKFEGIIHDCJHEG?IIFKJDEFFIMHKIDHDFFJJJIIICEEHJJIJJIJECIKJJILEI?FHFDGEEB X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.80729707 99 17 2417 29 101M = 2698 358 TAGCCAGGCGTGGTGGTGCACACCTGTAGTCCCAGCTACTCAGGAGGCTGAGGGGGAAGGACTGCTTGAGCCCAGGAGTTTGAGGCTGCTGTGAGCTGTGA :EBE?HH>CECHH;>?IDEFLDGNIJIGHG@B?AGF@ X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.101859832 99 17 2474 60 101M = 2762 388 AGGACTGCTTGAGCCCAGGAGTTTGAGGCTGCTGTGAGCTGTGATCGCATCACTGCATTCCAGCCCGGTGACAGAGTGAGTCACTGTCTCGAAAAAGAAAG ?ECGDLGFKGCKHGKKIGKGHGIIIKJEILJKLJFJ@EHGH:CHJL?HJHIJHMLLIJIEFJKIIE=HB>HGJHJIBEH>GGJHJHHFMG;H?FCHB6>CA X0:i:1 X1:i:0 MD:Z:90A10 RG:Z:ERR999999 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C +ERR229776.59500924 147 17 2490 60 101M = 2276 -314 AGGAGTTTGAGGCTGCTGTGAGCTGTGATCGCATCACTGCATTCCAGCCCGGTGACAGAGTGAGTCACTGTCTCGAAAAAGAAAGGAAGAAATAAAGAAAA IEFKEGJJIMIIDJJIJGJHMHHIHIGHI?HHJLHJJJLKJMKGJMKJI?DJJKJJMKLJIIKHJFCGIFIFJ;KIIIHKJGGJIHHIGGCB@FCIEEEEB X0:i:1 X1:i:0 MD:Z:74A26 RG:Z:ERR999999 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:D@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@CEC +ERR229776.5983641 147 17 2506 60 101M = 2267 -339 TGTGAGCTGTGATCGCATCACTGCATTCCAGCCCGGTGACAGAGTGAGTCACTGTCTCGAAAAAGAAAGGAAGAAATAAAGAAAACAAATAAAAATAATAG GDGGKHHJGGEIKAGHHKIKHKJHKMKEGNJJ?;LIKJJCJJNGJKLHKHCJHFFEK>GJJJJKFIJKIJHJIIIHHIHKJGGHGFHGGGBBEFCEFEEI@ X0:i:1 X1:i:0 MD:Z:58A42 RG:Z:ERR999999 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:B@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.52727770 163 17 2538 60 101M = 2848 395 CCGGAGACAGAGTGAGTCACTGTCTCGAAAAAGAAAGGAAGAAATAAAGCAAACAAATAAAAATAATAGTGCAGACAAAAGGCCTTGACCCATCTAGCTTT @0=>12?7?C;8I=0;9>#AH@ECA9=9=0().D=:;CKBE'450120:7+@C=E4C6E@CE5ACFI@D<@>9G=?;?E*=3HEKKJJCHKKHFHGJKLIILLGJLLLJJMMJJIMMMJJMHKKEEJGKLJKMLMKJJILKGLHJKJIIMIIIMFFIGIGGKFGE X0:i:1 X1:i:0 MD:Z:17A83 RG:Z:ERR999999 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.18618553 163 17 2570 60 101M = 2828 358 GAAAGGAAGAAATAAAGAAAACAAATAAAAATAATAGTGCAGACAAAAGGCCTTGACCCATCTAGCTTTGGCCCTCAGCATCAACCGCTAGATACGTCCCT @>DGC8=FEC>CGDIEHCACFGFKKAFHKJBDDCJ X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@E +ERR229776.83543817 99 17 2577 60 77M24S = 2821 288 AGAAATAAAGAAAACAAATAAAAATAATAGTGCAGACAAAAGGCCTTGACCCATCTAGCTTTGGCCCTCAGCATCAACCGCTAGATACGTCCCTCCCTTTC 4::A:>A>G8)>F<>ADDHDCGAJ<=JB,*EB797,>HHL@C95=/:EC=@@FC>GEJHC=479788BI96F0EKK######################### X0:i:1 X1:i:0 XC:i:77 MD:Z:77 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.66162627 99 17 2602 60 101M = 2766 264 AATAGTGCAGACAAAAGGCCTTGACCCATCTAGCTTTGGCCCTCAGCATCAACCGCTAGATACGTCCCTCCCTTTCTTCTGGGGCACAGGTCACACTCTCT ?DFGEHGFHIHGJEKKGGJJLJKKJLLIIKMIFHMJJIIJLLKJJIJKHJKMKFAJLJKLJKGBHJIFKGHHLHIJMIIGF>BCGJGKDCJIJGGFKFIEH X0:i:1 X1:i:0 MD:Z:101 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@J +ERR229776.36854728 99 17 2628 60 99M2S = 2910 357 CATCTAGCTTTGGCCCTCAGCATCAACCGCTAGATACGTCCCTCCCTTTCTTCTGGGGCACAGGTCACACTCTCTTCCAGGTCTAGGATGCAGCTGAGGGG 4GFEJG@EKG=@.BEGJ+AHFCFCGLGGD/E9CGADGFH?GDKGLFIAHDJ@BHGLEFDGEE=DDGIBFB### X0:i:1 X1:i:0 XC:i:99 MD:Z:99 RG:Z:ERR999999 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B@@@ +ERR229776.80729707 147 17 2698 29 23S78M = 2417 -358 TGCTTCTGGGGCACAGGTCACACTCTCTTCCAGGTCTATGATTCAGCTGAGGGGTGCCACTCTTACCATCTAATCTGTGCGCTTATTTACTCTGCTTTAGT ########################HI<4*16J>9**D?/?:9**HC)F3A'6B3F/;1.(((>/2&-5=*;,3HA<':0+('/(;/*7.(7%;'.2C@481 XC:i:78 MD:Z:15G3G15C21C7C12 AM:i:29 NM:i:5 SM:i:29 MQ:i:29 XT:A:M BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.94440410 147 17 2716 60 101M = 2419 -397 TGCAGCTGAGGGGTGCCCCTCTTACCATCTAATCTGTGCCCTTATTTCCTCTGCTTTAGTGAGGAAGAGGCCCCTGGTCCATGAAGGGGCCTTTCAGAGAC DEFJHGD>7E>ADGG@:9HJBIEADHGGGIHJJFGA>A?99DEKGFCC=4<%DGG;@BCCEDDF### X0:i:1 X1:i:0 XC:i:99 MD:Z:99 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.45483038 99 17 2750 60 101M = 3055 353 TGTGCCCTTATTTCCTCTGCTTTAGTGAGGAAGAGGCCCCTGGTCCATGAAGGGGCCTTTCAGAGACGGGGACCCCTGAGGAGCCCCGAGCAGCAGCCGTC BFHGGFFLHHGIIJKLKKJKLJJIHIKKMLLLLLMFEKMMNLMJLLJJJKMIFCFLILKLLKMLNLICHBEJ3AFAEEKCBCDGFIF;?=CCHFFEEC83; X0:i:1 X1:i:0 MD:Z:101 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.78014576 99 17 2757 60 91M10S = 2948 291 TTATTTCCTCTGCTTTAGTGAGGAAGAGGCCCCTGGTCCATGAAGGGGCCTTTCAGAGACGGGGACCCCTGAGGAGCCCCGAGCAGCAGCCGTCGTGTCTC BFGGGHGFKHIIIHIJFKHIKJLILLKLJKKMLMJLFJLJJJLNMMMMLMMKLMKMLKLJBJJFGCGFFECGHFB@HFFF/7@67?9E@F########### X0:i:1 X1:i:0 XC:i:91 MD:Z:91 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.101859832 147 17 2762 60 101M = 2474 -388 TCCTCTGCTTTAGTGAGGAAGAGGCCCCTGGTCCATGAAGGGGCCTTTCAGAGACGGGGACCCCTGAGGAGCCCCGAGCAGCAGCCGTCGTGTCTCACCCA <8=DBIGIHJGIDJIMHICFA?BGEFAG9FEGAAJ@CC?@DCFHAJ>>811?C;85FEHCBHA>@K8EE=3@<@EHB=;HI>FF?EB@FF=C5CBA@ X0:i:1 X1:i:0 MD:Z:101 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.66162627 147 17 2766 60 101M = 2602 -264 CTGCTTTAGTGAGGAAGAGGCCCCTGGTCCATGAAGGGGCCTTTCAGAGACGGGGACCCCTGAGGAGCCCCGAGCAGCAGCCGTCGTGTCTCACCCAGGGT EHGCA-@LEEDGHEFLEMHB?B?@FGEIDG?CA?FC>ACD1??@;AEAGCGGAAJKGFHK=IEB?LGCEFFHDCG#:3?EBFBGDF X0:i:1 X1:i:0 MD:Z:90T10 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B +ERR229776.44852854 83 17 2817 60 101M = 2547 -370 GGGGACCCCTGAGGAGCCCCGAGCAGCAGCCGTCGTGTCTCACCCAGGGTGTCTGAAACAGATGTGGAGGTCTCGGGTGAGGCGTGGCTCAGATACAGGGA BCC?6ABEHFILIIJJGGG;IGIHMIHIHF?EH?HKHLKLKKMMLNMMJKKMMKMKLKKNLJKKKLMMLIKJLBKLJJLLLKBIIKJFKIIHHHIHKEEFB X0:i:1 X1:i:0 MD:Z:101 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:CBA@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.83543817 147 17 2821 60 56S45M = 2577 -288 TCTGCTTTGGTGAGGAAGAGGCCCCGGGTCCATGAAGGGGCCTTTCAGAGACGGGGGCCCCTGAGGAGCCCCGAGCAGCAGCCGTCGTGTCTCACCCAGGG #########################################################7,,/?4:@2;'B6#'01'8,2'4&8.;H29?@:+&'-13CH;-1 X0:i:1 X1:i:0 XC:i:45 MD:Z:0A44 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.18618553 83 17 2828 60 101M = 2570 -358 AGGAGCCCCGAGCAGCAGCCGTCGTGTCTCACCCAGGGTGTCTGAAACAGATGTGGAGGTCTCGGGTGAGGCGTGGCTCAGATACAGGGAGTGGCCCACAG #B7@??990GHIIMFDEICAGH?FHCD<+@FEEHHIIIJILKKLKJKLNLJKKKMLMMJKIGBKIJJMMKK>GJLKJIKLLIHEJKJJIKEHGHE@EFDK? X0:i:1 X1:i:0 MD:Z:101 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.91229453 99 17 2831 60 101M = 3084 353 AGCCCCGAGCAGCAGCCGTCGTGTCTCACCCAGGGTGTCTGAAACAGATGTGGAGGTCTCGGGTGAGGCGTGGCTCAGATACAGGGAGTGGCCCACAGCTC ?CGEEF?HBGFIGFKJJABI@JIIIKKJJLKJKLLABEHLJLLMKKILJJJJFKKHGFLI=DD?BGFEG>@BBFIJKIKGIHJIG@HHHFKGEF:E7 X0:i:1 X1:i:0 XC:i:86 MD:Z:86 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.7004516 163 17 2878 60 101M = 3107 329 ATGTGGAGGTCTCGGGTGAGGCGTGGCTCAGATACAGGGAGTGGCCCACAGCTCGGCCTGTCTTTGAAAGGCCACGTGACCTGGCCCACGGCTGGCAGGTG @EEFECDFD;:JG0C=?D;AGJ?GGGJEI<=JHHHHJKIKE>CFIKLGGE?HIH6?CAF>GBKBA9GIGB?EDFE@IHGFGHIGEFFJG:@FIC@EDB?6B X0:i:1 X1:i:0 MD:Z:101 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D +ERR229776.36854728 147 17 2910 60 25S76M = 2628 -357 GGTCTCGGGTGAGGCGTGGCTCAGATACAGGGAGTGGCCCACAGCTCGGCCTGTCTTTGAAAGGCCACGTGACCTGGCCCACGGCTGGCAGGTGGGACCCA ##########################HHKC9,>ABC?;DBGAH=8;;IEE<>2?HB@C>HCF7<;2G79===)C@5&=*B@86FEEHA@B9:<797DB3;@ X0:i:1 X1:i:0 XC:i:76 MD:Z:76 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.28172972 163 17 2918 60 101M = 3194 376 GTGGCCCACAGCTCGGCCTGTCTTTGAAAGGCCACGTGACCTGGCCCACGGCTGGCAGGTGGGACCCAGCTGCAGGGGGCCAGCAGCACCCACAGCAGCCA BFECEDAFC@CGJH?GIIGGHIJIIGJHHD;A;@=D@9BE>:D=BHI9;;A"99>><@>BCEEE=CFEFIBAC# X0:i:1 X1:i:0 MD:Z:78T22 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.78014576 147 17 2948 60 101M = 2757 -291 GCCACGTGACCTGGCCCACGGCTGGCAGGTGGGACCCAGCTGCAGGGGTCCAGCAGCACCCACAGCAGCCACCTGTGGCAGGGAGGAGCTTGTGGTACAGT C@AB=GIC>BDHFFG@@??HHFHGEEIGHHHFBCFFIHHDJJEFMLHJKFEFHILEF>IHGGIIHJIHHI?EKIIHJJEJJHEJIDJHHIB@ED@EFEIDB X0:i:1 X1:i:0 MD:Z:101 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.19870548 163 17 2964 60 101M = 3254 390 CACGGCTGGCAGGTGGGACCCAGCTGCAGGGGTCCAGCAGCACCCACAGCAGCCACCTGTGGCAGGGAGGAGCTTGTGGTACAGTGGACAGGCCCTGCCCA ADDECGIGHJHBFH:F=:<9D??FIKJIGJHCHLGIHIEABDE@CGDDFFAFA?CDE@E9B?6>4B@@FAA6E6@5*>1=B>DB X0:i:1 X1:i:0 MD:Z:101 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.91036639 147 17 2967 60 101M = 2776 -291 GGCTGGCAGGTGGGACCCAGCTGCAGGGGTCCAGCAGCACCCACAGCAGCCACCTGTGGCAGGGAGGAGCTTGTGGTACAGTGGACAGGCCCTGCCCAGAT 53AFE?BAHGJIHIBCCEDIGIF=GGGGHKCFKF@F=?CGLJGBKIIKGG?:IJJJJKLJKLKJLKKKIKHB@HICHBHKHFEHGFJHGFBCFE@CEIFEB X0:i:1 X1:i:0 MD:Z:101 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.11173812 99 17 3034 60 101M = 3333 399 AGCTTGTGGTACAGTGGACAGGCCCTGCCCAGATGGCCCCCCGCCTGCCTGTGGAAGTTGACCAGACCATTTGTCACAGCAGGTAAGACTCTGCTTTCTGG ?CFKBHGHEHFGHEIGDHHILKLLLMIIKLJJKIJIKILMMM>JIMIHIMJFCDJLG0ADIHIGCGDEHHHEHIIKHKHGJIG8GKHKGNIMIIKGDFCEA X0:i:1 X1:i:0 MD:Z:70C30 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@GF +ERR229776.45483038 147 17 3055 60 52S49M = 2750 -353 GCCCCCACAGCAGCCACCTGTGGCAGGGAGGAGCTTGTGGTACAGTGGACAGGCCCTGCCCAGATGGCCCCCCGCCTGCCTGTGGAAGTTGACCAGACCAT #####################################################A54-7=90;?5::24>EAB?DH@DE X0:i:1 X1:i:0 MD:Z:101 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@FJ +ERR229776.59323675 163 17 3154 60 101M = 3389 335 TGGAATTCCTGTCCATCTGGCAGGTGGGCATTGAAACTGGTTTAAAAATGTCACACCATAGGCCGGGCACAGTGGCTCACGCCTGTAATCCCAGCCCTTTG @B?ECD9@8@GCII88GHF<9:FIIILLLLHFJEHHJJHIJGKJGI?@BJJJJKDB>DKDJC<@EEBHFLGF?EIAGEHCCD@2ABEACFHDCC#9@?###### X0:i:1 X1:i:0 XC:i:96 MD:Z:91T3T0 AM:i:37 NM:i:2 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.28172972 83 17 3194 60 101M = 2918 -376 TTTAAAAATGTCACACCATAGGCCGGGCACAGTGGCTCACGCCTGTAATCCCAGCCCTTTGGGAGGCCAGGGTGGGTGGATCACTTGAGGTCAGGAGTTCA BDFCHIEIJGKDHIJHIJIMHGG?IHIHJHKHJJGCGFKBMKMKJJLKLJJIIJFJMMMKMMMLMKFHLMKJJLLJIKIIKGDKLIKKIGHHKFGLDIHFB X0:i:1 X1:i:0 MD:Z:101 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:ABA@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@D +ERR229776.453972 81 17 3215 37 2S99M * 0 0 AGGCCGGGCACAGTGGCTCACGCCTGTAATCCCAGCCCTTTGGGAGGCCAGGGTGGGTGGATCACTTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACAT ###>6FEBCCE@HGDIIHDG?GEIICHHF@FBBIGHDFFF1JMLLLJCIMLIHFLIHJIJFGE?KLJMMHCDKMLLKJLIIJEB@KJKIEGIGHFHBFEE? X0:i:1 X1:i:0 XC:i:99 MD:Z:99 AM:i:37 NM:i:0 SM:i:37 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.41226651 99 17 3242 60 101M = 3478 336 TCCCAGCCCTTTGGGAGGCCAGGGTGGGTGGATCACTTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGTGAAACCCCGTCTACTAAAAATACAAA BFEEGHHFGKGIIEKJKGJHIJIIIIIIEIJKJKJIMKLLMJJJKMMGKDCIJLKLGIJFIGHCBFDHFEIHBEBCKHHDHHI?GIJJGNIHHJGDGEGDD X0:i:1 X1:i:0 MD:Z:101 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@IIK +ERR229776.19870548 83 17 3254 60 101M = 2964 -390 GGGAGGCCAGGGTGGGTGGATCACTTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGTGAAACCCCGTCTACTAAAAATACAAAAATTAGCCTGGC DEFIFHBEIIIDHFIGKHGIKCHIGKKOJILHMJKNHKGJIEKIMJMJDDJIJGAKKLKKLKKMKJJLLLCIKJIIJIJJJJHDEJIIIIGKHLHFGGEFB X0:i:1 X1:i:0 MD:Z:101 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:CCA@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.43420834 99 17 3270 60 101M = 3494 324 TGGATCACTTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGGGAAACCCCGTCTACTAAAAATACAAAAATTAGCCTGGCGTGGGGGCGCATGCCT ?ECHGGHFKIBJHJFGHKBJJIJKJMHKIKJMLLMIJKMKNKKJLI%@GMKHILH?EEHFAJJMMMDFBDIJJJGHGJDDHLDCG;HDA#77=FIJFJIJ=JJIG;EJEFBIKKJFE:GFD8/9:*E@EE3%DJ;D2BDD@ X0:i:1 X1:i:0 MD:Z:101 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:IH@G@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.94803111 163 17 3384 60 101M = 3606 322 CTTGGGAAGCTGAGGGATGAGAACTGCTTGAACCTGGGAGGCAGACGTTGCAGTGAGCTGAGATCACGCCACTGCACTCCAGCCTGGGCAACAGAGTAAGA BIEECCDHEBEGIBIGIGGHJIJHKIJKIHGLIJLJKKKLKKJKKJBIJIEJKJKKKIMJKHLEFIF@HFGDKGHIFLHHIHIHMIGBGJHGJIJHHGEFG X0:i:1 X1:i:0 MD:Z:101 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B +ERR229776.91011602 83 17 3387 60 101M = 3102 -385 GGGAAGCTGAGGGATGAGAACTGCTTGAACCTGGGAGGCAGACGTTGCAGTGAGCTGAGATCACGCCACTGCACTCCAGCCTGGGCAACAGAGTAAGACTC DDFFKHHFIMIHIJKGLIHIIHKIGJIDHIJKIJKNLLLNLKCKNKMJNKKMMJKKHNMJLIFAJJHIHIIHGLKIGJKKLIKKKJIHILGKFHHLEFDGB X0:i:1 X1:i:0 MD:Z:101 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:CBA@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.59323675 83 17 3389 60 101M = 3154 -335 GAAGCTGAGGGATGAGAACTGCTTGAACCTGGGAGGCAGACGTTGCAGTGAGCTGAGATCACGCCACTGCACTCCAGCCTGGGCAACAGAGTAAGACTCTG A5IGFFHGIIIJKINGEGIGI;KHE?1IHHJJKMJJHMKJBKNKMJMHGIMJIJLKJHKIE?GFFJKJEFEHKEIKIEGIFHC;AFHIGL@HHLGIGHDH? X0:i:1 X1:i:0 MD:Z:101 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.5896825 83 17 3415 60 101M = 3144 -371 ACCTGGGAGGCAGACGTTGCAGTGAGCTGAGATCACGCCACTGCACTCCAGCCTGGGCAACAGAGTAAGACTCTGTCTCAAAAAAAAAAAAATCACACCAT @>>ADEB1CA>FB277FJIFJ;=B18+/A098D=55?==:<>(;0=7BBH@>BEHFCBBC99?JA6@G7.A;?:7:AJGJJJJIJJIGIIGGIFHGEEFE? X0:i:1 X1:i:0 MD:Z:101 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@A +ERR229776.43002343 163 17 3466 29 43M58S = 3687 321 CCTGGGCAACAGAGTAAGACTCTGTCTCAAAAAAAAAAAAATAACACCATTTTGGCTTCAGAATTCATATCCTCCTGCAAGGATATATACGCGAGAAATTA 58=>BB1BB659IJHIGHHF:IFBBBHBFAG?G@HFCF;AGFDG>:AECFEEGAA X0:i:1 X1:i:0 MD:Z:101 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:C@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@C +ERR229776.43420834 147 17 3494 60 101M = 3270 -324 AAAAAAAAAAAAATCACACCATTTTGGCTTCAGATTGCATATCCTCCTGCAAGGATATATACGCGTGAAATTCAAGTCAATGACAAATCAGAAAAAAAAAC A9>D?@DFHHFFG9?577GHGD;IIGHGIGFKFFGDEBGACABDIB>I?G?HGKICIA9F<=>9>IGIIHJ@HIKCDDHGG<>GGCGCDJBBEFCFFEC<@ X0:i:1 X1:i:0 MD:Z:93G7 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:G@CICDGHJIEDB@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@BC@CCB@@@ +ERR229776.98041640 147 17 3494 60 46S55M = 3175 -373 CCCGCCCCGCCACCCCAGCCTGGGCAACAGGGTAAGCCTCCGTCTAAAAAAAAAAAAAATCACACCATTTTGGCTTCAGATTGCATATCCTCCTGCAAGGA ###############################################?DHGJJJHE?HD9;D;0@HD?:J7>:5>8GIIJHFGHJIHIIIINIGMIIGHFDED X0:i:1 X1:i:0 MD:Z:57G43 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.98929975 83 17 3553 60 101M = 3302 -351 TACGCGTGAAATTCAAGTCAATGACAAATCAGAAAAAAAAACATATATATACGCAAACCAGTATCCTACTGTGTGTGTCGTTTGTTGTGTTTTCGACAGCT A?>E?FIIFFJKKIFNGKIKJHIHIIEHJHLHDDDCCKJCGJJJKJJJJFFBLJKIFMKMJJJLJJJFLKIJIJJJJK@ILLIILIIFGKIKI?GHGKGEB X0:i:1 X1:i:0 MD:Z:34G66 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.105205152 99 17 3562 60 93M8S = 3856 394 AATTCAAGTCAATGACAAATCAGAAAAAAAAACATATATATACGCAAACCAGTATCCTACTGTGTGTGTCGTTTGTTGTGTTTTCGACAGCTGTCCGTGTT ?D>?9HF>@ECDFDCDF;HBDCIID9797+7.7B>6=HL######### X0:i:1 X1:i:0 XC:i:93 MD:Z:25G67 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:AF@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.30258628 163 17 3583 60 101M = 3859 349 AGAAAAAAAAACATATATATACGCAAAACAGTATCCTACTGTGTGTGTCGTTTGTTGTGGTTTCTACAGCTGTCCGTGTGATAATAATTCCTCTAGTTCAA @@GCHH;6=>ECF=G4D==2BC*:=)6)'/-/4107;+4+@=E7,CBC:;C;BLB?HDGGB X0:i:1 X1:i:0 MD:Z:4G22C31T4G14T21 AM:i:25 NM:i:5 SM:i:25 MQ:i:60 XT:A:U BQ:Z:OOVRWWJELKO@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@IG +ERR229776.15284212 99 17 3585 60 88M13S = 3809 324 AAAAAAAAACATATATATACGCAAACCAGTATCCTACTGTGTGTGTCGTTTGTTGTGTTTTCGACAGCTGTCCGTGTTATAATAATTCCTCTAGTTCAAAT ?DEDDFFEIECHI;HHHAHI>HGLLGKIJGHFHCJIHEAGF:FJJDC8GIDFJBCFBHDGGH5GCFCBC=:AF/1826-7FJEIJHI############## X0:i:1 X1:i:0 XC:i:88 MD:Z:2G85 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:MRSRRTRPQ@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.15906182 163 17 3598 60 101M = 3862 364 TATATACGCAAACCAGTATCCTACTGTGTGTGTCGTTTGTTGTGTTTTCGACAGCTGTCCGTGTTATAATAATTCCTCTAGTTCAAATTTATTCATTTTTA BFEEEE@EKCDGA@>G@D?HJIIC;?=CD@JK?#;BJJ5DECBIABFDGHHCGFE?DJDGJGKDGI5BEIKHFFIKD-BHEFEGMGIIKGIJJIJGJGJDJFJ?FMMKHNKIKKNNNLDMKLNLKKKLMCKKKNKKJLKJKKMKLKKMJMJMKKKKJLLIIIJJHJJKIHHGHJIGFFB X0:i:1 X1:i:0 MD:Z:101 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.15603458 163 17 3626 60 101M = 3846 320 TGTGTCGTTTGTTGTGTTTTCGACAGCTGTCCGTGTTATAATAATTCCTCTAGTTCAAATTTATTCATTTTTAACTTCATAGTACCACATTCTACACACTG @EADDC9A@B@GH@GBCFB>>3CD?=;E@9>H;C;IJBIIIIIJIJHILHCBAF;=GI@BJDJE>>CFHKHIINE:BHIGH4E?EHJGG>AFMIFIEHAJ4 X0:i:1 X1:i:0 MD:Z:101 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@B@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.80842527 99 17 3639 60 101M = 3844 305 GTGTTTTCGACAGCTGTCCGTGTTATAATAATTCCTCTAGTTCAAATTTATTCATTTTTAACTTCATAGTACCACATTCTACACACTGCCCATGTCCCCTC AGEFGHHG?JEIHJLJIKK@IJJJIJJMJJMJKMKMMMJMKKMKNNKKLJKLMKKLKLLKMKNLLKKKNLKKMKJJLLLLLJLILIPLJKILJIIGHFEJD X0:i:1 X1:i:0 MD:Z:101 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.84503264 163 17 3670 60 101M = 3903 331 TTCCTCTAGTTCAAATTTATTCATTTTTAACTTCATAGTACCACATTCTACACACTGCCCATGTCCCCTCAAGCTTCCCCTGGCTCCTGCAACCACAAATC AEFCIEFFEB,CEHH?*;6936?956.-2%7)=C@3?BB.6C891FDGFJ?==>D@A:/DEB5@4BDG@D@ X0:i:1 X1:i:0 MD:Z:101 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:EG@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B +ERR229776.78993145 147 17 3760 60 101M = 3530 -330 AACCACAAATCTACTCTCTGCCTCTGTGGGTTGACCTATTCTGGACACGTCATAGAAATAGAGTCCTGCAACACGTGGCCGTCTGTGTCTGGCTTCTCTCG 1@DGHHHFIJE@:CKDGIJIFHJBFBFGIHJJEFCHGEKEIIHGJGFAIKDJJMLJJIILDKIKIKIHHJEBBAIHJJE?HHIGGCGHHGABEHDEGEH9A X0:i:1 X1:i:0 MD:Z:101 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.102280357 83 17 3772 60 101M = 3516 -356 ACTCTCTGCCTCTGTGGGTTGACCTATTCTGGACACGTCATAGAAATAGAGTCCTGCAACACGTGGCCGTCTGTGTCTGGCTTCTCTCGCTTAGCATCTTG ;EGFFHIFGIKIKGJIHGHJIDGIJHIJHIGGGHG>HLJJJNIJKKJMJNKLMKJLLJJJDCKKLKJAIGLJIJGIJJLKJLICJGJAIIIHKHHHIGHHB X0:i:1 X1:i:0 MD:Z:101 AM:i:37 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.60297548 147 17 3785 60 101M = 3736 -149 GTGGGTTGACCTATTCTGGACACGTCATAGAAATAGAGTCCTGCAACACGTGGCCGTCTGTGTCTGGCTTCTCTCGCTTAGCATCTTGTTTCCAAGGTCCT @GFFFGJIJGIIHHKHJHHIHF@FIHIJLIHIFFJHJAGAIIHDGFDGAIEGHIAIKHIJIJKKIJKGKJD@IIAJKKEKJGDDJCGEE:,BJIGFGEFHFEBALJGJ?K4E;KILICFJELIFKJB>AHAF@HFGEGGGC? X0:i:1 X1:i:0 MD:Z:90A10 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.105205152 147 17 3856 60 101M = 3562 -394 TCTCGCTTAGCATCTTGTTTCCAAGGTCCTCCCACAGTGTAGCATGCACCTGCTACACTCCTTCTTAGGGCTGATATTCCGCGCACCTGCTACACTCCTTC #BE=GGHILIIHKHHJGJHJDHEKD;+EBF?C>FFJ?E?DCIFEIGB>=HGBDILKGIFB>FI=9*=<><'?;C69?8,6?DD253-72,D9>: X0:i:1 X1:i:0 MD:Z:80A20 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.30258628 83 17 3859 60 27S74M = 3583 -349 TCGTGGCCGTCTGTGTCTGGCTTCTCTCGCTTAGCATCTTGTTTCCAAGGTCCTCCCACAGTGTAGCATGCACCTGCTACACTCCTTCTTAGGGCTGATAT ############################FLLJHF-.LGLKHKKHCIBLHBHDB?@@;7IH=9>7/5HIE+A@EHICFFIGIJ@AGI?>KHAGEFGHE:DE7 X0:i:1 X1:i:0 XC:i:74 MD:Z:74 AM:i:25 NM:i:0 SM:i:37 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.15906182 83 17 3862 60 101M = 3598 -364 TTAGCATCTTGTTTCCAAGGTCCTCCCACAGTGTAGCATGCACCTGCTACACTCCTTCTTAGGGCTGATATTCCGCGCACCTGCTACACTCCTTCTTATGG FEFFGGJHCKHHKKGHILFE@:EBCFIIHLEHHIMHEEIFBEGJJJKIIBAIGJMMLMMJMIIJIJKJJJMGLAKAKFFEJIDGHIHCJK@GJJHJGGHEB X0:i:1 X1:i:0 MD:Z:74A26 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:D@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ +ERR229776.104583040 99 17 3884 37 84M17S = 4097 298 CTCCCACAGTGTAGCATGCACCTGCTACACTCCTTCTTAGGGCTGATATTCCGCGCACCTGCTACACTCCTTCTTATGGCTGATATTCCACGCACCTGCTA ?HFEEHFHBC7EGAHIHCHFDHL?HJ=FI48C>KFJL=EKCCJJJALKHJLJLLIIHJFKHIIGGKJHCG?EFBHIGDCF>F@CCDFEGEGFF@ X0:i:1 X1:i:0 MD:Z:39A61 AM:i:37 NM:i:1 SM:i:37 MQ:i:60 XT:A:U BQ:Z:A@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@B +ERR229776.84503264 83 17 3903 60 2S99M = 3670 -331 GCCCCTGCTACCCTCCTTCTTAGGGCTGATATTCCGCGCCCCTGCTACCCTCCTTCTTATGGCTGATATTCCACGCACCTGCTACACTCCTTCTTAGGGCT ###?DDA5-;91@B:HBJ<:89-=F65868-%4C9E5-=>9C+9C9H;AFC7GEBCCJJILKJHHAIHELLIJJD=C>IFEIIJIJHLEEGEB X0:i:1 X1:i:0 XC:i:99 MD:Z:0A8A23A3A8A52 AM:i:25 NM:i:5 SM:i:25 MQ:i:60 XT:A:U BQ:Z:@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ diff --git a/test/mpileup/mpileup.5.out b/test/mpileup/mpileup.5.out new file mode 100644 index 0000000..5aa9d4a --- /dev/null +++ b/test/mpileup/mpileup.5.out @@ -0,0 +1,529 @@ +##fileformat=VCFv4.2 +##FILTER= +##contig= +##ALT= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT HG00100 HG00101 HG00102 +17 100 . C <*> 0 . DP=18;ADF=17,0;ADR=0,0;AD=17,0;I16=17,0,0,0,688,29762,0,0,958,55682,0,0,332,7446,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,27,189:9:0:9,0:0,0:9,0 0,9,108:3:0:3,0:0,0:3,0 0,15,134:5:0:5,0:0,0:5,0 +17 101 . C <*> 0 . DP=18;ADF=17,0;ADR=0,0;AD=17,0;I16=17,0,0,0,650,27530,0,0,958,55682,0,0,331,7303,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,27,182:9:0:9,0:0,0:9,0 0,9,99:3:0:3,0:0,0:3,0 0,15,132:5:0:5,0:0,0:5,0 +17 102 . C <*> 0 . DP=18;ADF=17,0;ADR=0,0;AD=17,0;I16=17,0,0,0,695,30453,0,0,958,55682,0,0,330,7178,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,27,188:9:0:9,0:0,0:9,0 0,9,111:3:0:3,0:0,0:3,0 0,15,139:5:0:5,0:0,0:5,0 +17 103 . T <*> 0 . DP=18;ADF=16,0;ADR=0,0;AD=16,0;I16=16,0,0,0,692,31998,0,0,929,54841,0,0,323,7035,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,24,189:8:0:8,0:0,0:8,0 0,9,108:3:0:3,0:0,0:3,0 0,15,147:5:0:5,0:0,0:5,0 +17 104 . G <*> 0 . DP=18;ADF=15,0;ADR=0,0;AD=15,0;I16=15,0,0,0,611,26723,0,0,900,54000,0,0,295,6259,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,24,178:8:0:8,0:0,0:8,0 0,6,89:2:0:2,0:0,0:2,0 0,15,133:5:0:5,0:0,0:5,0 +17 105 . G <*> 0 . DP=19;ADF=17,0;ADR=0,0;AD=17,0;I16=17,0,0,0,604,23936,0,0,989,58441,0,0,317,6751,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,27,170:9:0:9,0:0,0:9,0 0,9,97:3:0:3,0:0,0:3,0 0,15,125:5:0:5,0:0,0:5,0 +17 106 . G <*> 0 . DP=19;ADF=17,0;ADR=0,0;AD=17,0;I16=17,0,0,0,644,26574,0,0,989,58441,0,0,299,6093,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,190:10:0:10,0:0,0:10,0 0,6,85:2:0:2,0:0,0:2,0 0,15,124:5:0:5,0:0,0:5,0 +17 107 . C <*> 0 . DP=19;ADF=17,0;ADR=0,0;AD=17,0;I16=17,0,0,0,694,30064,0,0,989,58441,0,0,313,6543,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,27,192:9:0:9,0:0,0:9,0 0,9,108:3:0:3,0:0,0:3,0 0,15,136:5:0:5,0:0,0:5,0 +17 108 . C <*> 0 . DP=19;ADF=17,0;ADR=0,0;AD=17,0;I16=17,0,0,0,692,30148,0,0,989,58441,0,0,310,6420,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,27,190:9:0:9,0:0,0:9,0 0,9,108:3:0:3,0:0,0:3,0 0,15,135:5:0:5,0:0,0:5,0 +17 109 . T <*> 0 . DP=19;ADF=17,0;ADR=0,0;AD=17,0;I16=17,0,0,0,741,34273,0,0,989,58441,0,0,307,6319,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,27,195:9:0:9,0:0,0:9,0 0,9,110:3:0:3,0:0,0:3,0 0,15,150:5:0:5,0:0,0:5,0 +17 110 . G <*> 0 . DP=19;ADF=17,0;ADR=0,0;AD=17,0;I16=17,0,0,0,704,31276,0,0,989,58441,0,0,304,6240,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,27,194:9:0:9,0:0,0:9,0 0,9,104:3:0:3,0:0,0:3,0 0,15,136:5:0:5,0:0,0:5,0 +17 111 . G <*> 0 . DP=19;ADF=16,0;ADR=0,0;AD=16,0;I16=16,0,0,0,584,24362,0,0,929,54841,0,0,272,5416,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,167:10:0:10,0:0,0:10,0 0,6,88:2:0:2,0:0,0:2,0 0,12,118:4:0:4,0:0,0:4,0 +17 112 . C <*> 0 . DP=19;ADF=17,0;ADR=0,0;AD=17,0;I16=17,0,0,0,680,29854,0,0,989,58441,0,0,296,6052,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,27,191:9:0:9,0:0,0:9,0 0,9,95:3:0:3,0:0,0:3,0 0,15,135:5:0:5,0:0,0:5,0 +17 113 . A <*> 0 . DP=19;ADF=16,0;ADR=0,0;AD=16,0;I16=16,0,0,0,645,28035,0,0,960,57600,0,0,266,5318,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,27,176:9:0:9,0:0,0:9,0 0,6,87:2:0:2,0:0,0:2,0 0,15,139:5:0:5,0:0,0:5,0 +17 114 . C <*> 0 . DP=19;ADF=17,0;ADR=0,0;AD=17,0;I16=17,0,0,0,674,28788,0,0,989,58441,0,0,286,5856,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,27,182:9:0:9,0:0,0:9,0 0,9,103:3:0:3,0:0,0:3,0 0,15,133:5:0:5,0:0,0:5,0 +17 115 . C <*> 0 . DP=21;ADF=18,0;ADR=0,0;AD=18,0;I16=18,0,0,0,708,30546,0,0,1049,62041,0,0,274,5490,0,0;QS=3,0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,189:10:0:10,0:0,0:10,0 0,6,89:2:0:2,0:0,0:2,0 0,18,147:6:0:6,0:0,0:6,0 +17 116 . A <*> 0 . DP=21;ADF=17,0;ADR=1,0;AD=18,0;I16=17,1,0,0,727,31755,0,0,1049,62041,0,0,253,5079,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,27,183:9:0:9,0:0,0:9,0 0,6,90:2:0:2,0:0,0:2,0 0,21,175:7:0:6,0:1,0:7,0 +17 117 . G <*> 0 . DP=21;ADF=17,0;ADR=1,0;AD=18,0;I16=17,1,0,0,712,30478,0,0,1049,62041,0,0,249,5019,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,27,183:9:0:9,0:0,0:9,0 0,6,85:2:0:2,0:0,0:2,0 0,21,177:7:0:6,0:1,0:7,0 +17 118 . G <*> 0 . DP=20;ADF=16,0;ADR=1,0;AD=17,0;I16=16,1,0,0,636,26574,0,0,958,55682,0,0,266,5426,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,27,175:9:0:9,0:0,0:9,0 0,3,60:1:0:1,0:0,0:1,0 0,21,162:7:0:6,0:1,0:7,0 +17 119 . G <*> 0 . DP=19;ADF=16,0;ADR=1,0;AD=17,0;I16=16,1,0,0,629,26439,0,0,958,55682,0,0,267,5553,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,24,175:8:0:8,0:0,0:8,0 0,6,73:2:0:2,0:0,0:2,0 0,21,160:7:0:6,0:1,0:7,0 +17 120 . A <*> 0 . DP=19;ADF=16,0;ADR=1,0;AD=17,0;I16=16,1,0,0,672,29188,0,0,958,55682,0,0,264,5518,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,24,175:8:0:8,0:0,0:8,0 0,6,83:2:0:2,0:0,0:2,0 0,21,171:7:0:6,0:1,0:7,0 +17 121 . G <*> 0 . DP=19;ADF=16,0;ADR=1,0;AD=17,0;I16=16,1,0,0,662,28460,0,0,958,55682,0,0,260,5454,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,24,181:8:0:8,0:0,0:8,0 0,6,80:2:0:2,0:0,0:2,0 0,21,168:7:0:6,0:1,0:7,0 +17 122 . C <*> 0 . DP=20;ADF=17,0;ADR=1,0;AD=18,0;I16=17,1,0,0,716,31224,0,0,1018,59282,0,0,256,5410,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,24,181:8:0:8,0:0,0:8,0 0,9,99:3:0:3,0:0,0:3,0 0,21,178:7:0:6,0:1,0:7,0 +17 123 . T <*> 0 . DP=18;ADF=15,0;ADR=1,0;AD=16,0;I16=15,1,0,0,661,29997,0,0,898,52082,0,0,255,5385,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,167:7:0:7,0:0,0:7,0 0,9,112:3:0:3,0:0,0:3,0 0,18,166:6:0:5,0:1,0:6,0 +17 124 . T <*> 0 . DP=19;ADF=17,0;ADR=1,0;AD=18,0;I16=17,1,0,0,626,24802,0,0,987,56523,0,0,279,6003,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,27,154:9:0:9,0:0,0:9,0 0,9,104:3:0:3,0:0,0:3,0 0,18,154:6:0:5,0:1,0:6,0 +17 125 . A <*> 0 . DP=18;ADF=15,0;ADR=1,0;AD=16,0;I16=15,1,0,0,611,25689,0,0,898,52082,0,0,254,5340,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,154:7:0:7,0:0,0:7,0 0,9,104:3:0:3,0:0,0:3,0 0,18,162:6:0:5,0:1,0:6,0 +17 126 . A <*> 0 . DP=18;ADF=16,0;ADR=1,0;AD=17,0;I16=16,1,0,0,648,27366,0,0,927,52923,0,0,279,5947,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,24,162:8:0:8,0:0,0:8,0 0,9,107:3:0:3,0:0,0:3,0 0,18,174:6:0:5,0:1,0:6,0 +17 127 . C <*> 0 . DP=18;ADF=16,0;ADR=1,0;AD=17,0;I16=16,1,0,0,646,26972,0,0,927,52923,0,0,279,5949,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,24,163:8:0:8,0:0,0:8,0 0,9,109:3:0:3,0:0,0:3,0 0,18,160:6:0:5,0:1,0:6,0 +17 128 . A <*> 0 . DP=18;ADF=16,0;ADR=1,0;AD=17,0;I16=16,1,0,0,673,28797,0,0,927,52923,0,0,279,5971,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,24,169:8:0:8,0:0,0:8,0 0,9,111:3:0:3,0:0,0:3,0 0,18,162:6:0:5,0:1,0:6,0 +17 129 . A <*> 0 . DP=17;ADF=15,0;ADR=1,0;AD=16,0;I16=15,1,0,0,645,27891,0,0,867,49323,0,0,280,6012,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,24,168:8:0:8,0:0,0:8,0 0,9,113:3:0:3,0:0,0:3,0 0,15,159:5:0:4,0:1,0:5,0 +17 130 . A <*> 0 . DP=17;ADF=15,0;ADR=1,0;AD=16,0;I16=15,1,0,0,641,27295,0,0,867,49323,0,0,281,6071,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,24,169:8:0:8,0:0,0:8,0 0,9,113:3:0:3,0:0,0:3,0 0,15,152:5:0:4,0:1,0:5,0 +17 131 . C <*> 0 . DP=16;ADF=14,0;ADR=1,0;AD=15,0;I16=14,1,0,0,606,25732,0,0,838,48482,0,0,256,5472,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,167:7:0:7,0:0,0:7,0 0,9,110:3:0:3,0:0,0:3,0 0,15,147:5:0:4,0:1,0:5,0 +17 132 . A <*> 0 . DP=16;ADF=14,0;ADR=1,0;AD=15,0;I16=14,1,0,0,627,27579,0,0,838,48482,0,0,256,5514,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,169:7:0:7,0:0,0:7,0 0,9,110:3:0:3,0:0,0:3,0 0,15,151:5:0:4,0:1,0:5,0 +17 133 . T <*> 0 . DP=15;ADF=13,0;ADR=2,0;AD=15,0;I16=13,2,0,0,584,22816,0,0,838,48482,0,0,282,6196,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,163:7:0:7,0:0,0:7,0 0,9,105:3:0:2,0:1,0:3,0 0,15,150:5:0:4,0:1,0:5,0 +17 134 . C <*> 0 . DP=15;ADF=13,0;ADR=2,0;AD=15,0;I16=13,2,0,0,607,24653,0,0,838,48482,0,0,283,6267,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,177:7:0:7,0:0,0:7,0 0,9,105:3:0:2,0:1,0:3,0 0,15,152:5:0:4,0:1,0:5,0 +17 135 . T <*> 0 . DP=15;ADF=13,0;ADR=2,0;AD=15,0;I16=13,2,0,0,600,24178,0,0,838,48482,0,0,284,6352,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,173:7:0:7,0:0,0:7,0 0,9,106:3:0:2,0:1,0:3,0 0,15,156:5:0:4,0:1,0:5,0 +17 136 . G <*> 0 . DP=15;ADF=13,0;ADR=2,0;AD=15,0;I16=13,2,0,0,574,22258,0,0,838,48482,0,0,286,6450,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,172:7:0:7,0:0,0:7,0 0,9,105:3:0:2,0:1,0:3,0 0,15,134:5:0:4,0:1,0:5,0 +17 137 . T <*> 0 . DP=15;ADF=13,0;ADR=2,0;AD=15,0;I16=13,2,0,0,563,21377,0,0,838,48482,0,0,289,6561,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,160:7:0:7,0:0,0:7,0 0,9,104:3:0:2,0:1,0:3,0 0,15,139:5:0:4,0:1,0:5,0 +17 138 . C <*> 0 . DP=15;ADF=13,0;ADR=2,0;AD=15,0;I16=13,2,0,0,584,23088,0,0,838,48482,0,0,291,6637,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,172:7:0:7,0:0,0:7,0 0,9,108:3:0:2,0:1,0:3,0 0,15,142:5:0:4,0:1,0:5,0 +17 139 . C <*> 0 . DP=15;ADF=13,0;ADR=2,0;AD=15,0;I16=13,2,0,0,554,20790,0,0,838,48482,0,0,292,6680,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,161:7:0:7,0:0,0:7,0 0,9,106:3:0:2,0:1,0:3,0 0,15,143:5:0:4,0:1,0:5,0 +17 140 . A <*> 0 . DP=15;ADF=13,0;ADR=2,0;AD=15,0;I16=13,2,0,0,583,22789,0,0,838,48482,0,0,292,6690,0,0;QS=3,0;MQSB=0.576923;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,163:7:0:7,0:0,0:7,0 0,9,107:3:0:2,0:1,0:3,0 0,15,153:5:0:4,0:1,0:5,0 +17 141 . G <*> 0 . DP=14;ADF=12,0;ADR=2,0;AD=14,0;I16=12,2,0,0,534,20750,0,0,778,44882,0,0,292,6664,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,158:6:0:6,0:0,0:6,0 0,9,108:3:0:2,0:1,0:3,0 0,15,142:5:0:4,0:1,0:5,0 +17 142 . C <*> 0 . DP=14;ADF=12,0;ADR=2,0;AD=14,0;I16=12,2,0,0,503,18593,0,0,778,44882,0,0,292,6650,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,157:6:0:6,0:0,0:6,0 0,9,97:3:0:2,0:1,0:3,0 0,15,129:5:0:4,0:1,0:5,0 +17 143 . G <*> 0 . DP=14;ADF=11,0;ADR=2,0;AD=13,0;I16=11,2,0,0,415,13657,0,0,718,41282,0,0,285,6599,0,0;QS=3,0;MQSB=0.590909;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,128:6:0:6,0:0,0:6,0 0,9,95:3:0:2,0:1,0:3,0 0,12,97:4:0:3,0:1,0:4,0 +17 144 . A <*> 0 . DP=14;ADF=12,0;ADR=2,0;AD=14,0;I16=12,2,0,0,519,19725,0,0,778,44882,0,0,291,6609,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,152:6:0:6,0:0,0:6,0 0,9,105:3:0:2,0:1,0:3,0 0,15,129:5:0:4,0:1,0:5,0 +17 145 . A <*> 0 . DP=14;ADF=12,0;ADR=2,0;AD=14,0;I16=12,2,0,0,527,20289,0,0,778,44882,0,0,290,6584,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,153:6:0:6,0:0,0:6,0 0,9,106:3:0:2,0:1,0:3,0 0,15,138:5:0:4,0:1,0:5,0 +17 146 . T <*> 0 . DP=14;ADF=12,0;ADR=2,0;AD=14,0;I16=12,2,0,0,514,19484,0,0,778,44882,0,0,289,6573,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,152:6:0:6,0:0,0:6,0 0,9,103:3:0:2,0:1,0:3,0 0,15,128:5:0:4,0:1,0:5,0 +17 147 . A <*> 0 . DP=14;ADF=12,0;ADR=2,0;AD=14,0;I16=12,2,0,0,515,19213,0,0,778,44882,0,0,288,6576,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,150:6:0:6,0:0,0:6,0 0,9,99:3:0:2,0:1,0:3,0 0,15,140:5:0:4,0:1,0:5,0 +17 148 . C <*> 0 . DP=14;ADF=12,0;ADR=2,0;AD=14,0;I16=12,2,0,0,541,21019,0,0,778,44882,0,0,286,6542,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,157:6:0:6,0:0,0:6,0 0,9,106:3:0:2,0:1,0:3,0 0,15,146:5:0:4,0:1,0:5,0 +17 149 . C <*> 0 . DP=14;ADF=12,0;ADR=2,0;AD=14,0;I16=12,2,0,0,512,19326,0,0,778,44882,0,0,283,6471,0,0;QS=3,0;MQSB=0.583333;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,148:6:0:6,0:0,0:6,0 0,9,109:3:0:2,0:1,0:3,0 0,15,140:5:0:4,0:1,0:5,0 +17 150 . T <*> 0 . DP=13;ADF=11,0;ADR=2,0;AD=13,0;I16=11,2,0,0,511,20251,0,0,749,44041,0,0,280,6362,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,153:6:0:6,0:0,0:6,0 0,6,84:2:0:1,0:1,0:2,0 0,15,152:5:0:4,0:1,0:5,0 +17 151 . G <*> 0 . DP=13;ADF=11,0;ADR=2,0;AD=13,0;I16=11,2,0,0,506,19826,0,0,749,44041,0,0,277,6263,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,157:6:0:6,0:0,0:6,0 0,6,84:2:0:1,0:1,0:2,0 0,15,144:5:0:4,0:1,0:5,0 +17 152 . C <*> 0 . DP=14;ADF=12,0;ADR=2,0;AD=14,0;I16=12,2,0,0,543,21283,0,0,809,47641,0,0,274,6174,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,168:7:0:7,0:0,0:7,0 0,6,84:2:0:1,0:1,0:2,0 0,15,146:5:0:4,0:1,0:5,0 +17 153 . A <*> 0 . DP=14;ADF=12,0;ADR=2,0;AD=14,0;I16=12,2,0,0,536,20594,0,0,809,47641,0,0,272,6096,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,156:7:0:7,0:0,0:7,0 0,6,81:2:0:1,0:1,0:2,0 0,15,153:5:0:4,0:1,0:5,0 +17 154 . T <*> 0 . DP=14;ADF=12,0;ADR=2,0;AD=14,0;I16=12,2,0,0,523,20051,0,0,809,47641,0,0,270,6030,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,159:7:0:7,0:0,0:7,0 0,6,83:2:0:1,0:1,0:2,0 0,15,139:5:0:4,0:1,0:5,0 +17 155 . C <*> 0 . DP=14;ADF=12,0;ADR=2,0;AD=14,0;I16=12,2,0,0,542,21254,0,0,809,47641,0,0,268,5976,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,172:7:0:7,0:0,0:7,0 0,6,85:2:0:1,0:1,0:2,0 0,15,139:5:0:4,0:1,0:5,0 +17 156 . C <*> 0 . DP=14;ADF=12,0;ADR=2,0;AD=14,0;I16=12,2,0,0,536,20884,0,0,809,47641,0,0,266,5934,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,163:7:0:7,0:0,0:7,0 0,6,84:2:0:1,0:1,0:2,0 0,15,150:5:0:4,0:1,0:5,0 +17 157 . C <*> 0 . DP=14;ADF=12,0;ADR=2,0;AD=14,0;I16=12,2,0,0,555,22081,0,0,809,47641,0,0,264,5904,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,169:7:0:7,0:0,0:7,0 0,6,85:2:0:1,0:1,0:2,0 0,15,149:5:0:4,0:1,0:5,0 +17 158 . T <*> 0 . DP=14;ADF=12,0;ADR=2,0;AD=14,0;I16=12,2,0,0,568,23154,0,0,809,47641,0,0,262,5886,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,170:7:0:7,0:0,0:7,0 0,6,84:2:0:1,0:1,0:2,0 0,15,159:5:0:4,0:1,0:5,0 +17 159 . A <*> 0 . DP=15;ADF=12,0;ADR=2,0;AD=14,0;I16=12,2,0,0,519,19467,0,0,809,47641,0,0,260,5880,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,157:7:0:7,0:0,0:7,0 0,6,83:2:0:1,0:1,0:2,0 0,15,135:5:0:4,0:1,0:5,0 +17 160 . G <*> 0 . DP=15;ADF=13,0;ADR=2,0;AD=15,0;I16=13,2,0,0,547,20633,0,0,869,51241,0,0,259,5887,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,165:7:0:7,0:0,0:7,0 0,6,85:2:0:1,0:1,0:2,0 0,18,139:6:0:5,0:1,0:6,0 +17 161 . A <*> 0 . DP=15;ADF=13,0;ADR=2,0;AD=15,0;I16=13,2,0,0,568,21610,0,0,869,51241,0,0,258,5908,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,157:7:0:7,0:0,0:7,0 0,6,83:2:0:1,0:1,0:2,0 0,18,162:6:0:5,0:1,0:6,0 +17 162 . A <*> 0 . DP=15;ADF=13,0;ADR=2,0;AD=15,0;I16=13,2,0,0,557,21139,0,0,869,51241,0,0,255,5843,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,147:7:0:7,0:0,0:7,0 0,6,87:2:0:1,0:1,0:2,0 0,18,167:6:0:5,0:1,0:6,0 +17 163 . G <*> 0 . DP=14;ADF=12,0;ADR=2,0;AD=14,0;I16=12,2,0,0,503,18645,0,0,809,47641,0,0,253,5791,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,153:7:0:7,0:0,0:7,0 0,6,79:2:0:1,0:1,0:2,0 0,15,138:5:0:4,0:1,0:5,0 +17 164 . T <*> 0 . DP=14;ADF=12,0;ADR=2,0;AD=14,0;I16=12,2,0,0,460,15968,0,0,809,47641,0,0,252,5750,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,131:6:0:6,0:0,0:6,0 0,6,79:2:0:1,0:1,0:2,0 0,18,136:6:0:5,0:1,0:6,0 +17 165 . G <*> 0 . DP=14;ADF=10,0;ADR=2,0;AD=12,0;I16=10,2,0,0,456,17460,0,0,689,40441,0,0,226,5094,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,149:6:0:6,0:0,0:6,0 0,6,80:2:0:1,0:1,0:2,0 0,12,122:4:0:3,0:1,0:4,0 +17 166 . A <*> 0 . DP=14;ADF=11,0;ADR=2,0;AD=13,0;I16=11,2,0,0,496,19138,0,0,749,44041,0,0,227,5077,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,145:6:0:6,0:0,0:6,0 0,6,82:2:0:1,0:1,0:2,0 0,15,148:5:0:4,0:1,0:5,0 +17 167 . A <*> 0 . DP=14;ADF=11,0;ADR=2,0;AD=13,0;I16=11,2,0,0,477,17851,0,0,749,44041,0,0,227,5071,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,132:6:0:6,0:0,0:6,0 0,6,86:2:0:1,0:1,0:2,0 0,15,147:5:0:4,0:1,0:5,0 +17 168 . G <*> 0 . DP=14;ADF=12,0;ADR=2,0;AD=14,0;I16=12,2,0,0,481,18015,0,0,809,47641,0,0,252,5702,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,145:6:0:6,0:0,0:6,0 0,6,82:2:0:1,0:1,0:2,0 0,18,140:6:0:5,0:1,0:6,0 +17 169 . C <*> 0 . DP=13;ADF=10,0;ADR=2,0;AD=12,0;I16=10,2,0,0,402,14224,0,0,689,40441,0,0,227,5045,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,15,106:5:0:5,0:0,0:5,0 0,6,76:2:0:1,0:1,0:2,0 0,15,145:5:0:4,0:1,0:5,0 +17 170 . C <*> 0 . DP=13;ADF=11,0;ADR=2,0;AD=13,0;I16=11,2,0,0,447,16383,0,0,749,44041,0,0,251,5601,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,15,128:5:0:5,0:0,0:5,0 0,6,80:2:0:1,0:1,0:2,0 0,18,143:6:0:5,0:1,0:6,0 +17 171 . A <*> 0 . DP=13;ADF=11,0;ADR=2,0;AD=13,0;I16=11,2,0,0,500,19366,0,0,749,44041,0,0,250,5546,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,15,134:5:0:5,0:0,0:5,0 0,6,81:2:0:1,0:1,0:2,0 0,18,166:6:0:5,0:1,0:6,0 +17 172 . C <*> 0 . DP=13;ADF=10,0;ADR=2,0;AD=12,0;I16=10,2,0,0,439,16395,0,0,689,40441,0,0,241,5441,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,15,138:5:0:5,0:0,0:5,0 0,6,75:2:0:1,0:1,0:2,0 0,15,129:5:0:4,0:1,0:5,0 +17 173 . C <*> 0 . DP=13;ADF=11,0;ADR=2,0;AD=13,0;I16=11,2,0,0,435,15225,0,0,749,44041,0,0,248,5478,0,0;QS=3,0;MQSB=0.5;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,15,121:5:0:5,0:0,0:5,0 0,6,76:2:0:1,0:1,0:2,0 0,18,146:6:0:5,0:1,0:6,0 +17 174 . G <*> 0 . DP=13;ADF=11,0;ADR=1,0;AD=12,0;I16=11,1,0,0,351,10685,0,0,689,40441,0,0,238,5364,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,15,111:5:0:5,0:0,0:5,0 0,3,27:1:0:1,0:0,0:1,0 0,18,117:6:0:5,0:1,0:6,0 +17 175 . C <*> 0 . DP=14;ADF=13,0;ADR=1,0;AD=14,0;I16=13,1,0,0,511,19161,0,0,809,47641,0,0,249,5463,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,143:6:0:6,0:0,0:6,0 0,3,41:1:0:1,0:0,0:1,0 0,21,175:7:0:6,0:1,0:7,0 +17 176 . C <*> 0 . DP=14;ADF=13,0;ADR=1,0;AD=14,0;I16=13,1,0,0,489,17733,0,0,809,47641,0,0,251,5477,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,146:6:0:6,0:0,0:6,0 0,3,44:1:0:1,0:0,0:1,0 0,21,152:7:0:6,0:1,0:7,0 +17 177 . C <*> 0 . DP=14;ADF=13,0;ADR=1,0;AD=14,0;I16=13,1,0,0,488,17328,0,0,809,47641,0,0,253,5507,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,138:6:0:6,0:0,0:6,0 0,3,44:1:0:1,0:0,0:1,0 0,21,158:7:0:6,0:1,0:7,0 +17 178 . A <*> 0 . DP=14;ADF=13,0;ADR=1,0;AD=14,0;I16=13,1,0,0,519,19485,0,0,809,47641,0,0,254,5502,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,147:6:0:6,0:0,0:6,0 0,3,42:1:0:1,0:0,0:1,0 0,21,172:7:0:6,0:1,0:7,0 +17 179 . A <*> 0 . DP=14;ADF=13,0;ADR=1,0;AD=14,0;I16=13,1,0,0,478,17278,0,0,809,47641,0,0,255,5511,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,134:6:0:6,0:0,0:6,0 0,3,44:1:0:1,0:0,0:1,0 0,21,170:7:0:6,0:1,0:7,0 +17 180 . A <*> 0 . DP=14;ADF=12,0;ADR=1,0;AD=13,0;I16=12,1,0,0,425,14653,0,0,749,44041,0,0,250,5498,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,126:6:0:6,0:0,0:6,0 0,3,43:1:0:1,0:0,0:1,0 0,18,148:6:0:5,0:1,0:6,0 +17 181 . G <*> 0 . DP=14;ADF=11,0;ADR=1,0;AD=12,0;I16=11,1,0,0,450,17152,0,0,689,40441,0,0,233,5233,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,156:6:0:6,0:0,0:6,0 0,3,41:1:0:1,0:0,0:1,0 0,15,138:5:0:4,0:1,0:5,0 +17 182 . A <*> 0 . DP=15;ADF=14,0;ADR=1,0;AD=15,0;I16=14,1,0,0,515,18235,0,0,869,51241,0,0,258,5622,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,150:7:0:7,0:0,0:7,0 0,3,43:1:0:1,0:0,0:1,0 0,21,159:7:0:6,0:1,0:7,0 +17 183 . C <*> 0 . DP=15;ADF=13,0;ADR=1,0;AD=14,0;I16=13,1,0,0,483,17419,0,0,809,47641,0,0,235,5063,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,159:7:0:7,0:0,0:7,0 0,3,40:1:0:1,0:0,0:1,0 0,18,139:6:0:5,0:1,0:6,0 +17 184 . A <*> 0 . DP=15;ADF=14,0;ADR=1,0;AD=15,0;I16=14,1,0,0,535,19667,0,0,869,51241,0,0,262,5770,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,158:7:0:7,0:0,0:7,0 0,3,41:1:0:1,0:0,0:1,0 0,21,163:7:0:6,0:1,0:7,0 +17 185 . C <*> 0 . DP=15;ADF=13,0;ADR=1,0;AD=14,0;I16=13,1,0,0,487,17295,0,0,809,47641,0,0,238,5192,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,150:7:0:7,0:0,0:7,0 0,3,38:1:0:1,0:0,0:1,0 0,18,160:6:0:5,0:1,0:6,0 +17 186 . G <*> 0 . DP=15;ADF=12,0;ADR=1,0;AD=13,0;I16=12,1,0,0,381,11429,0,0,749,44041,0,0,239,5253,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,117:6:0:6,0:0,0:6,0 0,3,32:1:0:1,0:0,0:1,0 0,18,124:6:0:5,0:1,0:6,0 +17 187 . C <*> 0 . DP=14;ADF=13,0;ADR=1,0;AD=14,0;I16=13,1,0,0,511,18979,0,0,809,47641,0,0,266,5952,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,147:6:0:6,0:0,0:6,0 0,3,38:1:0:1,0:0,0:1,0 0,21,172:7:0:6,0:1,0:7,0 +17 188 . C <*> 0 . DP=14;ADF=13,0;ADR=1,0;AD=14,0;I16=13,1,0,0,496,18042,0,0,809,47641,0,0,267,5989,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,147:6:0:6,0:0,0:6,0 0,3,37:1:0:1,0:0,0:1,0 0,21,162:7:0:6,0:1,0:7,0 +17 189 . C <*> 0 . DP=15;ADF=13,0;ADR=2,0;AD=15,0;I16=13,2,0,0,552,20504,0,0,838,48482,0,0,268,6040,0,0;QS=3,0;MQSB=0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,152:6:0:6,0:0,0:6,0 0,6,67:2:0:1,0:1,0:2,0 0,21,167:7:0:6,0:1,0:7,0 +17 190 . A <*> 0 . DP=15;ADF=12,0;ADR=2,0;AD=14,0;I16=12,2,0,0,500,18230,0,0,778,44882,0,0,243,5381,0,0;QS=3,0;MQSB=0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,138:6:0:6,0:0,0:6,0 0,6,68:2:0:1,0:1,0:2,0 0,18,159:6:0:5,0:1,0:6,0 +17 191 . T <*> 0 . DP=15;ADF=13,0;ADR=2,0;AD=15,0;I16=13,2,0,0,534,19276,0,0,838,48482,0,0,267,5939,0,0;QS=3,0;MQSB=0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,143:6:0:6,0:0,0:6,0 0,6,67:2:0:1,0:1,0:2,0 0,21,169:7:0:6,0:1,0:7,0 +17 192 . G <*> 0 . DP=15;ADF=13,0;ADR=2,0;AD=15,0;I16=13,2,0,0,499,17439,0,0,838,48482,0,0,266,5890,0,0;QS=3,0;MQSB=0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,143:6:0:6,0:0,0:6,0 0,6,67:2:0:1,0:1,0:2,0 0,21,151:7:0:6,0:1,0:7,0 +17 193 . T <*> 0 . DP=15;ADF=13,0;ADR=2,0;AD=15,0;I16=13,2,0,0,505,17811,0,0,838,48482,0,0,265,5859,0,0;QS=3,0;MQSB=0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,140:6:0:6,0:0,0:6,0 0,6,63:2:0:1,0:1,0:2,0 0,21,157:7:0:6,0:1,0:7,0 +17 194 . C <*> 0 . DP=14;ADF=12,0;ADR=2,0;AD=14,0;I16=12,2,0,0,467,16569,0,0,778,44882,0,0,265,5845,0,0;QS=3,0;MQSB=0;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,142:6:0:6,0:0,0:6,0 0,6,67:2:0:1,0:1,0:2,0 0,18,145:6:0:5,0:1,0:6,0 +17 195 . C <*> 0 . DP=14;ADF=11,0;ADR=3,0;AD=14,0;I16=11,3,0,0,503,18647,0,0,747,42123,0,0,266,5846,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,159:6:0:5,0:1,0:6,0 0,6,71:2:0:1,0:1,0:2,0 0,18,160:6:0:5,0:1,0:6,0 +17 196 . A <*> 0 . DP=14;ADF=11,0;ADR=3,0;AD=14,0;I16=11,3,0,0,482,17400,0,0,747,42123,0,0,268,5862,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,166:6:0:5,0:1,0:6,0 0,6,69:2:0:1,0:1,0:2,0 0,18,138:6:0:5,0:1,0:6,0 +17 197 . G <*> 0 . DP=14;ADF=11,0;ADR=3,0;AD=14,0;I16=11,3,0,0,481,17391,0,0,747,42123,0,0,270,5894,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,164:6:0:5,0:1,0:6,0 0,6,68:2:0:1,0:1,0:2,0 0,18,134:6:0:5,0:1,0:6,0 +17 198 . C <*> 0 . DP=14;ADF=11,0;ADR=3,0;AD=14,0;I16=11,3,0,0,539,20957,0,0,747,42123,0,0,271,5893,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,172:6:0:5,0:1,0:6,0 0,6,70:2:0:1,0:1,0:2,0 0,18,164:6:0:5,0:1,0:6,0 +17 199 . T <*> 0 . DP=14;ADF=11,0;ADR=3,0;AD=14,0;I16=11,3,0,0,505,19197,0,0,747,42123,0,0,271,5861,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,162:6:0:5,0:1,0:6,0 0,6,73:2:0:1,0:1,0:2,0 0,18,154:6:0:5,0:1,0:6,0 +17 200 . T <*> 0 . DP=15;ADF=11,0;ADR=4,0;AD=15,0;I16=11,4,0,0,544,19918,0,0,776,42964,0,0,270,5798,0,0;QS=3,0;MQSB=0.0161635;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,161:6:0:5,0:1,0:6,0 0,9,89:3:0:1,0:2,0:3,0 0,18,154:6:0:5,0:1,0:6,0 +17 201 . A <*> 0 . DP=16;ADF=12,0;ADR=4,0;AD=16,0;I16=12,4,0,0,568,20416,0,0,836,46564,0,0,269,5703,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,171:7:0:6,0:1,0:7,0 0,9,89:3:0:1,0:2,0:3,0 0,18,157:6:0:5,0:1,0:6,0 +17 202 . A <*> 0 . DP=16;ADF=12,0;ADR=4,0;AD=16,0;I16=12,4,0,0,566,20590,0,0,836,46564,0,0,269,5627,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,178:7:0:6,0:1,0:7,0 0,9,84:3:0:1,0:2,0:3,0 0,18,163:6:0:5,0:1,0:6,0 +17 203 . C <*> 0 . DP=16;ADF=12,0;ADR=4,0;AD=16,0;I16=12,4,0,0,557,20119,0,0,836,46564,0,0,269,5571,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,166:7:0:6,0:1,0:7,0 0,9,90:3:0:1,0:2,0:3,0 0,18,153:6:0:5,0:1,0:6,0 +17 204 . C <*> 0 . DP=16;ADF=12,0;ADR=4,0;AD=16,0;I16=12,4,0,0,591,22379,0,0,836,46564,0,0,269,5535,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,173:7:0:6,0:1,0:7,0 0,9,91:3:0:1,0:2,0:3,0 0,18,163:6:0:5,0:1,0:6,0 +17 205 . T <*> 0 . DP=16;ADF=12,0;ADR=4,0;AD=16,0;I16=12,4,0,0,635,25281,0,0,836,46564,0,0,269,5519,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,188:7:0:6,0:1,0:7,0 0,9,95:3:0:1,0:2,0:3,0 0,18,173:6:0:5,0:1,0:6,0 +17 206 . G <*> 0 . DP=16;ADF=12,0;ADR=4,0;AD=16,0;I16=12,4,0,0,577,21337,0,0,836,46564,0,0,269,5523,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,180:7:0:6,0:1,0:7,0 0,9,89:3:0:1,0:2,0:3,0 0,18,143:6:0:5,0:1,0:6,0 +17 207 . C <*> 0 . DP=16;ADF=12,0;ADR=4,0;AD=16,0;I16=12,4,0,0,574,21076,0,0,836,46564,0,0,269,5547,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,179:7:0:6,0:1,0:7,0 0,9,93:3:0:1,0:2,0:3,0 0,18,151:6:0:5,0:1,0:6,0 +17 208 . A <*> 0 . DP=16;ADF=12,0;ADR=4,0;AD=16,0;I16=12,4,0,0,576,21486,0,0,836,46564,0,0,268,5540,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,184:7:0:6,0:1,0:7,0 0,9,93:3:0:1,0:2,0:3,0 0,18,154:6:0:5,0:1,0:6,0 +17 209 . T <*> 0 . DP=16;ADF=12,0;ADR=4,0;AD=16,0;I16=12,4,0,0,567,20475,0,0,836,46564,0,0,267,5551,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,173:7:0:6,0:1,0:7,0 0,9,91:3:0:1,0:2,0:3,0 0,18,146:6:0:5,0:1,0:6,0 +17 210 . C <*> 0 . DP=16;ADF=12,0;ADR=4,0;AD=16,0;I16=12,4,0,0,577,21109,0,0,836,46564,0,0,266,5580,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,185:7:0:6,0:1,0:7,0 0,9,92:3:0:1,0:2,0:3,0 0,18,151:6:0:5,0:1,0:6,0 +17 211 . C <*> 0 . DP=16;ADF=12,0;ADR=4,0;AD=16,0;I16=12,4,0,0,563,20227,0,0,836,46564,0,0,265,5627,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,172:7:0:6,0:1,0:7,0 0,9,92:3:0:1,0:2,0:3,0 0,18,153:6:0:5,0:1,0:6,0 +17 212 . C <*> 0 . DP=16;ADF=12,0;ADR=4,0;AD=16,0;I16=12,4,0,0,589,22179,0,0,836,46564,0,0,263,5643,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,181:7:0:6,0:1,0:7,0 0,9,92:3:0:1,0:2,0:3,0 0,18,152:6:0:5,0:1,0:6,0 +17 213 . T <*> 0 . DP=16;ADF=12,0;ADR=4,0;AD=16,0;I16=12,4,0,0,598,22838,0,0,836,46564,0,0,262,5678,0,0;QS=3,0;MQSB=0.0144756;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,181:7:0:6,0:1,0:7,0 0,9,95:3:0:1,0:2,0:3,0 0,18,165:6:0:5,0:1,0:6,0 +17 214 . A <*> 0 . DP=16;ADF=11,0;ADR=4,0;AD=15,0;I16=11,4,0,0,529,19401,0,0,776,42964,0,0,240,5248,0,0;QS=3,0;MQSB=0.0161635;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,176:7:0:6,0:1,0:7,0 0,9,92:3:0:1,0:2,0:3,0 0,15,118:5:0:4,0:1,0:5,0 +17 215 . G <*> 0 . DP=15;ADF=12,0;ADR=3,0;AD=15,0;I16=12,3,0,0,521,19073,0,0,807,45723,0,0,262,5754,0,0;QS=3,0;MQSB=0.0342181;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,185:7:0:6,0:1,0:7,0 0,9,90:3:0:1,0:2,0:3,0 0,15,105:5:0:5,0:0,0:5,0 +17 216 . A <*> 0 . DP=14;ADF=10,0;ADR=3,0;AD=13,0;I16=10,3,0,0,464,16900,0,0,687,38523,0,0,238,5166,0,0;QS=3,0;MQSB=0.040184;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,173:7:0:6,0:1,0:7,0 0,9,92:3:0:1,0:2,0:3,0 0,9,81:3:0:3,0:0,0:3,0 +17 217 . A <*> 0 . DP=14;ADF=11,0;ADR=3,0;AD=14,0;I16=11,3,0,0,515,19433,0,0,747,42123,0,0,264,5842,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,181:7:0:6,0:1,0:7,0 0,9,90:3:0:1,0:2,0:3,0 0,12,97:4:0:4,0:0,0:4,0 +17 218 . G <*> 0 . DP=14;ADF=11,0;ADR=3,0;AD=14,0;I16=11,3,0,0,507,18957,0,0,747,42123,0,0,265,5907,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,178:7:0:6,0:1,0:7,0 0,9,90:3:0:1,0:2,0:3,0 0,12,110:4:0:4,0:0,0:4,0 +17 219 . T <*> 0 . DP=14;ADF=11,0;ADR=3,0;AD=14,0;I16=11,3,0,0,470,16286,0,0,747,42123,0,0,266,5986,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,173:7:0:6,0:1,0:7,0 0,9,88:3:0:1,0:2,0:3,0 0,12,89:4:0:4,0:0,0:4,0 +17 220 . G <*> 0 . DP=14;ADF=10,0;ADR=3,0;AD=13,0;I16=10,3,0,0,485,18307,0,0,687,38523,0,0,242,5454,0,0;QS=3,0;MQSB=0.040184;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,188:7:0:6,0:1,0:7,0 0,9,88:3:0:1,0:2,0:3,0 0,9,80:3:0:3,0:0,0:3,0 +17 221 . A <*> 0 . DP=14;ADF=11,0;ADR=3,0;AD=14,0;I16=11,3,0,0,487,17615,0,0,747,42123,0,0,267,6135,0,0;QS=3,0;MQSB=0.0368832;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,176:7:0:6,0:1,0:7,0 0,9,88:3:0:1,0:2,0:3,0 0,12,101:4:0:4,0:0,0:4,0 +17 222 . A <*> 0 . DP=14;ADF=10,0;ADR=3,0;AD=13,0;I16=10,3,0,0,465,17367,0,0,687,38523,0,0,242,5578,0,0;QS=3,0;MQSB=0.040184;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,186:7:0:6,0:1,0:7,0 0,9,85:3:0:1,0:2,0:3,0 0,9,69:3:0:3,0:0,0:3,0 +17 223 . G <*> 0 . DP=13;ADF=9,0;ADR=3,0;AD=12,0;I16=9,3,0,0,405,14327,0,0,627,34923,0,0,243,5657,0,0;QS=3,0;MQSB=0.0443614;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,168:6:0:5,0:1,0:6,0 0,6,53:2:0:0,0:2,0:2,0 0,12,81:4:0:4,0:0,0:4,0 +17 224 . G <*> 0 . DP=12;ADF=9,0;ADR=3,0;AD=12,0;I16=9,3,0,0,379,12759,0,0,627,34923,0,0,270,6370,0,0;QS=3,0;MQSB=0.0443614;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,168:6:0:5,0:1,0:6,0 0,6,50:2:0:0,0:2,0:2,0 0,12,70:4:0:4,0:0,0:4,0 +17 225 . C <*> 0 . DP=12;ADF=8,0;ADR=3,0;AD=11,0;I16=8,3,0,0,382,13896,0,0,567,31323,0,0,261,6345,0,0;QS=3,0;MQSB=0.0497871;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,165:6:0:5,0:1,0:6,0 0,6,48:2:0:0,0:2,0:2,0 0,9,83:3:0:3,0:0,0:3,0 +17 226 . A <*> 0 . DP=13;ADF=8,0;ADR=3,0;AD=11,0;I16=8,3,0,0,381,13669,0,0,567,31323,0,0,248,5894,0,0;QS=3,0;MQSB=0.0497871;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,166:6:0:5,0:1,0:6,0 0,6,53:2:0:0,0:2,0:2,0 0,9,84:3:0:3,0:0,0:3,0 +17 227 . C <*> 0 . DP=13;ADF=8,0;ADR=4,0;AD=12,0;I16=8,4,0,0,406,14306,0,0,596,32164,0,0,267,6253,0,0;QS=3,0;MQSB=0.0249144;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,190:7:0:5,0:2,0:7,0 0,6,53:2:0:0,0:2,0:2,0 0,9,73:3:0:3,0:0,0:3,0 +17 228 . C <*> 0 . DP=13;ADF=9,0;ADR=4,0;AD=13,0;I16=9,4,0,0,417,14381,0,0,656,35764,0,0,292,6884,0,0;QS=3,0;MQSB=0.0211283;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,187:7:0:5,0:2,0:7,0 0,6,45:2:0:0,0:2,0:2,0 0,12,96:4:0:4,0:0,0:4,0 +17 229 . G <*> 0 . DP=13;ADF=9,0;ADR=3,0;AD=12,0;I16=9,3,0,0,358,11424,0,0,627,34923,0,0,270,6414,0,0;QS=3,0;MQSB=0.0443614;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,136:6:0:5,0:1,0:6,0 0,6,53:2:0:0,0:2,0:2,0 0,12,70:4:0:4,0:0,0:4,0 +17 230 . C <*> 0 . DP=13;ADF=9,0;ADR=4,0;AD=13,0;I16=9,4,0,0,461,16861,0,0,656,35764,0,0,292,6920,0,0;QS=3,0;MQSB=0.0211283;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,186:7:0:5,0:2,0:7,0 0,6,53:2:0:0,0:2,0:2,0 0,12,100:4:0:4,0:0,0:4,0 +17 231 . C <*> 0 . DP=13;ADF=7,0;ADR=4,0;AD=11,0;I16=7,4,0,0,414,15832,0,0,536,28564,0,0,247,5925,0,0;QS=3,0;MQSB=0.0401934;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,18,184:6:0:4,0:2,0:6,0 0,6,53:2:0:0,0:2,0:2,0 0,9,82:3:0:3,0:0,0:3,0 +17 232 . C <*> 0 . DP=14;ADF=9,0;ADR=4,0;AD=13,0;I16=9,4,0,0,471,17371,0,0,656,35764,0,0,267,6363,0,0;QS=3,0;MQSB=0.0211283;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,198:7:0:5,0:2,0:7,0 0,6,53:2:0:0,0:2,0:2,0 0,12,101:4:0:4,0:0,0:4,0 +17 233 . A <*> 0 . DP=14;ADF=10,0;ADR=4,0;AD=14,0;I16=10,4,0,0,496,18142,0,0,716,39364,0,0,292,6984,0,0;QS=3,0;MQSB=0.0183156;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,192:7:0:5,0:2,0:7,0 0,6,53:2:0:0,0:2,0:2,0 0,15,119:5:0:5,0:0,0:5,0 +17 234 . A <*> 0 . DP=14;ADF=10,0;ADR=4,0;AD=14,0;I16=10,4,0,0,502,18390,0,0,716,39364,0,0,292,6988,0,0;QS=3,0;MQSB=0.0183156;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,185:7:0:5,0:2,0:7,0 0,6,53:2:0:0,0:2,0:2,0 0,15,123:5:0:5,0:0,0:5,0 +17 235 . A <*> 0 . DP=14;ADF=9,0;ADR=4,0;AD=13,0;I16=9,4,0,0,476,17652,0,0,656,35764,0,0,267,6375,0,0;QS=3,0;MQSB=0.0211283;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,21,186:7:0:5,0:2,0:7,0 0,6,53:2:0:0,0:2,0:2,0 0,12,111:4:0:4,0:0,0:4,0 +17 236 . G <*> 0 . DP=15;ADF=11,0;ADR=4,0;AD=15,0;I16=11,4,0,0,501,17481,0,0,776,42964,0,0,290,6924,0,0;QS=3,0;MQSB=0.0161635;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,24,206:8:0:6,0:2,0:8,0 0,6,53:2:0:0,0:2,0:2,0 0,15,103:5:0:5,0:0,0:5,0 +17 237 . A <*> 0 . DP=14;ADF=9,0;ADR=4,0;AD=13,0;I16=9,4,0,0,465,16877,0,0,656,35764,0,0,266,6282,0,0;QS=3,0;MQSB=0.0211283;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,24,206:8:0:6,0:2,0:8,0 0,6,53:2:0:0,0:2,0:2,0 0,9,92:3:0:3,0:0,0:3,0 +17 238 . C <*> 0 . DP=14;ADF=10,0;ADR=4,0;AD=14,0;I16=10,4,0,0,482,17238,0,0,716,39364,0,0,292,6900,0,0;QS=3,0;MQSB=0.0183156;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,24,211:8:0:6,0:2,0:8,0 0,6,53:2:0:0,0:2,0:2,0 0,12,82:4:0:4,0:0,0:4,0 +17 239 . A <*> 0 . DP=15;ADF=10,0;ADR=5,0;AD=15,0;I16=10,5,0,0,525,19155,0,0,776,42964,0,0,292,6852,0,0;QS=3,0;MQSB=0.0497871;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,27,223:9:0:6,0:3,0:9,0 0,6,50:2:0:0,0:2,0:2,0 0,12,108:4:0:4,0:0,0:4,0 +17 240 . C <*> 0 . DP=15;ADF=10,0;ADR=5,0;AD=15,0;I16=10,5,0,0,512,17930,0,0,776,42964,0,0,292,6764,0,0;QS=3,0;MQSB=0.0497871;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,27,220:9:0:6,0:3,0:9,0 0,6,53:2:0:0,0:2,0:2,0 0,12,106:4:0:4,0:0,0:4,0 +17 241 . G <*> 0 . DP=15;ADF=9,0;ADR=5,0;AD=14,0;I16=9,5,0,0,444,14636,0,0,716,39364,0,0,269,6159,0,0;QS=3,0;MQSB=0.0561348;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,27,203:9:0:6,0:3,0:9,0 0,6,53:2:0:0,0:2,0:2,0 0,9,59:3:0:3,0:0,0:3,0 +17 242 . C <*> 0 . DP=15;ADF=10,0;ADR=5,0;AD=15,0;I16=10,5,0,0,555,21177,0,0,776,42964,0,0,292,6624,0,0;QS=3,0;MQSB=0.0497871;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,27,242:9:0:6,0:3,0:9,0 0,6,53:2:0:0,0:2,0:2,0 0,12,94:4:0:4,0:0,0:4,0 +17 243 . C <*> 0 . DP=16;ADF=9,0;ADR=5,0;AD=14,0;I16=9,5,0,0,523,19737,0,0,716,39364,0,0,284,6508,0,0;QS=3,0;MQSB=0.0561348;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,24,220:8:0:5,0:3,0:8,0 0,6,53:2:0:0,0:2,0:2,0 0,12,104:4:0:4,0:0,0:4,0 +17 244 . C <*> 0 . DP=16;ADF=10,0;ADR=6,0;AD=16,0;I16=10,6,0,0,620,24272,0,0,805,43805,0,0,298,6568,0,0;QS=3,0;MQSB=0.0253122;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,27,245:9:0:6,0:3,0:9,0 0,9,72:3:0:0,0:3,0:3,0 0,12,106:4:0:4,0:0,0:4,0 +17 245 . A <*> 0 . DP=17;ADF=10,0;ADR=7,0;AD=17,0;I16=10,7,0,0,649,24843,0,0,865,47405,0,0,299,6553,0,0;QS=3,0;MQSB=0.0509867;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,27,236:9:0:6,0:3,0:9,0 0,12,93:4:0:0,0:4,0:4,0 0,12,115:4:0:4,0:0,0:4,0 +17 246 . T <*> 0 . DP=18;ADF=10,0;ADR=8,0;AD=18,0;I16=10,8,0,0,649,23833,0,0,894,48246,0,0,301,6553,0,0;QS=3,0;MQSB=0.0286491;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,247:10:0:6,0:4,0:10,0 0,12,94:4:0:0,0:4,0:4,0 0,12,98:4:0:4,0:0,0:4,0 +17 247 . G <*> 0 . DP=18;ADF=10,0;ADR=8,0;AD=18,0;I16=10,8,0,0,642,23610,0,0,894,48246,0,0,304,6570,0,0;QS=3,0;MQSB=0.0286491;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,252:10:0:6,0:4,0:10,0 0,12,83:4:0:0,0:4,0:4,0 0,12,103:4:0:4,0:0,0:4,0 +17 248 . T <*> 0 . DP=18;ADF=10,0;ADR=8,0;AD=18,0;I16=10,8,0,0,636,22944,0,0,894,48246,0,0,307,6605,0,0;QS=3,0;MQSB=0.0286491;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,234:10:0:6,0:4,0:10,0 0,12,86:4:0:0,0:4,0:4,0 0,12,114:4:0:4,0:0,0:4,0 +17 249 . C <*> 0 . DP=18;ADF=10,0;ADR=8,0;AD=18,0;I16=10,8,0,0,656,24846,0,0,894,48246,0,0,310,6658,0,0;QS=3,0;MQSB=0.0286491;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,253:10:0:6,0:4,0:10,0 0,12,79:4:0:0,0:4,0:4,0 0,12,112:4:0:4,0:0,0:4,0 +17 250 . C <*> 0 . DP=19;ADF=10,0;ADR=9,0;AD=19,0;I16=10,9,0,0,694,26160,0,0,923,49087,0,0,311,6631,0,0;QS=3,0;MQSB=0.0168512;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,248:10:0:6,0:4,0:10,0 0,12,89:4:0:0,0:4,0:4,0 0,15,142:5:0:4,0:1,0:5,0 +17 251 . A <*> 0 . DP=19;ADF=9,0;ADR=9,0;AD=18,0;I16=9,9,0,0,688,26506,0,0,863,45487,0,0,313,6627,0,0;QS=3,0;MQSB=0.0208913;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,27,233:9:0:5,0:4,0:9,0 0,12,97:4:0:0,0:4,0:4,0 0,15,148:5:0:4,0:1,0:5,0 +17 252 . G <*> 0 . DP=18;ADF=8,0;ADR=9,0;AD=17,0;I16=8,9,0,0,641,24631,0,0,803,41887,0,0,304,6502,0,0;QS=3,0;MQSB=0.026526;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,27,243:9:0:5,0:4,0:9,0 0,12,91:4:0:0,0:4,0:4,0 0,12,121:4:0:3,0:1,0:4,0 +17 253 . C <*> 0 . DP=19;ADF=9,0;ADR=10,0;AD=19,0;I16=9,10,0,0,705,26921,0,0,892,46328,0,0,319,6687,0,0;QS=3,0;MQSB=0.0132999;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,27,247:9:0:5,0:4,0:9,0 0,12,86:4:0:0,0:4,0:4,0 0,18,155:6:0:4,0:2,0:6,0 +17 254 . T <*> 0 . DP=20;ADF=10,0;ADR=9,0;AD=19,0;I16=10,9,0,0,719,27517,0,0,892,46328,0,0,314,6670,0,0;QS=3,0;MQSB=0.00482795;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,254:10:0:6,0:4,0:10,0 0,9,72:3:0:0,0:3,0:3,0 0,18,164:6:0:4,0:2,0:6,0 +17 255 . T <*> 0 . DP=21;ADF=11,0;ADR=10,0;AD=21,0;I16=11,10,0,0,750,27076,0,0,1012,53528,0,0,328,6840,0,0;QS=3,0;MQSB=0.00822975;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,241:11:0:7,0:4,0:11,0 0,12,95:4:0:0,0:4,0:4,0 0,18,161:6:0:4,0:2,0:6,0 +17 256 . A <*> 0 . DP=22;ADF=11,0;ADR=11,0;AD=22,0;I16=11,11,0,0,811,30063,0,0,1049,54897,0,0,334,6956,0,0;QS=3,0;MQSB=0.00507916;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:7,0:4,0:11,0 0,15,110:5:0:0,0:5,0:5,0 0,18,166:6:0:4,0:2,0:6,0 +17 257 . T <*> 0 . DP=22;ADF=11,0;ADR=11,0;AD=22,0;I16=11,11,0,0,814,30420,0,0,1049,54897,0,0,341,7101,0,0;QS=3,0;MQSB=0.00507916;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,247:11:0:7,0:4,0:11,0 0,15,113:5:0:0,0:5,0:5,0 0,18,168:6:0:4,0:2,0:6,0 +17 258 . T <*> 0 . DP=22;ADF=11,0;ADR=11,0;AD=22,0;I16=11,11,0,0,791,28943,0,0,1049,54897,0,0,347,7225,0,0;QS=3,0;MQSB=0.00507916;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,254:11:0:7,0:4,0:11,0 0,15,116:5:0:0,0:5,0:5,0 0,18,155:6:0:4,0:2,0:6,0 +17 259 . C <*> 0 . DP=22;ADF=11,0;ADR=10,0;AD=21,0;I16=11,10,0,0,785,29809,0,0,1020,54056,0,0,332,6936,0,0;QS=3,0;MQSB=0.00822975;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:7,0:4,0:11,0 0,12,90:4:0:0,0:4,0:4,0 0,18,170:6:0:4,0:2,0:6,0 +17 260 . T <*> 0 . DP=21;ADF=10,0;ADR=11,0;AD=21,0;I16=10,11,0,0,829,32899,0,0,989,51297,0,0,360,7556,0,0;QS=3,0;MQSB=0.00660016;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:7,0:4,0:11,0 0,15,118:5:0:0,0:5,0:5,0 0,15,156:5:0:3,0:2,0:5,0 +17 261 . G <*> 0 . DP=21;ADF=10,0;ADR=11,0;AD=21,0;I16=10,11,0,0,735,27379,0,0,989,51297,0,0,367,7761,0,0;QS=3,0;MQSB=0.00660016;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,254:11:0:7,0:4,0:11,0 0,15,111:5:0:0,0:5,0:5,0 0,15,122:5:0:3,0:2,0:5,0 +17 262 . C <*> 0 . DP=22;ADF=10,0;ADR=12,0;AD=22,0;I16=10,12,0,0,806,30278,0,0,1049,54897,0,0,373,7941,0,0;QS=3,0;MQSB=0.0122507;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:7,0:4,0:11,0 0,15,99:5:0:0,0:5,0:5,0 0,18,164:6:0:3,0:3,0:6,0 +17 263 . C <*> 0 . DP=22;ADF=10,0;ADR=12,0;AD=22,0;I16=10,12,0,0,799,29717,0,0,1049,54897,0,0,380,8146,0,0;QS=3,0;MQSB=0.0122507;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:7,0:4,0:11,0 0,15,98:5:0:0,0:5,0:5,0 0,18,168:6:0:3,0:3,0:6,0 +17 264 . C <*> 0 . DP=22;ADF=10,0;ADR=12,0;AD=22,0;I16=10,12,0,0,821,31325,0,0,1049,54897,0,0,386,8326,0,0;QS=3,0;MQSB=0.0122507;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:7,0:4,0:11,0 0,15,104:5:0:0,0:5,0:5,0 0,18,172:6:0:3,0:3,0:6,0 +17 265 . A <*> 0 . DP=21;ADF=9,0;ADR=12,0;AD=21,0;I16=9,12,0,0,800,31906,0,0,989,51297,0,0,390,8380,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:7,0:4,0:11,0 0,15,114:5:0:0,0:5,0:5,0 0,15,129:5:0:2,0:3,0:5,0 +17 266 . G <*> 0 . DP=21;ADF=9,0;ADR=11,0;AD=20,0;I16=9,11,0,0,747,28155,0,0,960,50456,0,0,369,7833,0,0;QS=3,0;MQSB=0.0237479;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:7,0:4,0:11,0 0,12,97:4:0:0,0:4,0:4,0 0,15,138:5:0:2,0:3,0:5,0 +17 267 . T <*> 0 . DP=21;ADF=9,0;ADR=11,0;AD=20,0;I16=9,11,0,0,739,27465,0,0,960,50456,0,0,373,7935,0,0;QS=3,0;MQSB=0.0237479;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,254:11:0:7,0:4,0:11,0 0,12,101:4:0:0,0:4,0:4,0 0,15,149:5:0:2,0:3,0:5,0 +17 268 . T <*> 0 . DP=21;ADF=9,0;ADR=12,0;AD=21,0;I16=9,12,0,0,748,27708,0,0,989,51297,0,0,402,8686,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,238:11:0:7,0:4,0:11,0 0,15,110:5:0:0,0:5,0:5,0 0,15,156:5:0:2,0:3,0:5,0 +17 269 . C <*> 0 . DP=22;ADF=9,0;ADR=12,0;AD=21,0;I16=9,12,0,0,764,28632,0,0,989,51297,0,0,381,8211,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,36,255:12:0:7,0:5,0:12,0 0,12,91:4:0:0,0:4,0:4,0 0,15,154:5:0:2,0:3,0:5,0 +17 270 . C <*> 0 . DP=22;ADF=9,0;ADR=12,0;AD=21,0;I16=9,12,0,0,758,28146,0,0,989,51297,0,0,385,8337,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,36,255:12:0:7,0:5,0:12,0 0,12,96:4:0:0,0:4,0:4,0 0,15,143:5:0:2,0:3,0:5,0 +17 271 . T <*> 0 . DP=22;ADF=9,0;ADR=13,0;AD=22,0;I16=9,13,0,0,847,32935,0,0,1018,52138,0,0,413,9065,0,0;QS=3,0;MQSB=0.0109431;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,36,255:12:0:7,0:5,0:12,0 0,15,113:5:0:0,0:5,0:5,0 0,15,152:5:0:2,0:3,0:5,0 +17 272 . C <*> 0 . DP=22;ADF=9,0;ADR=12,0;AD=21,0;I16=9,12,0,0,809,31413,0,0,989,51297,0,0,390,8518,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,36,255:12:0:7,0:5,0:12,0 0,12,96:4:0:0,0:4,0:4,0 0,15,149:5:0:2,0:3,0:5,0 +17 273 . T <*> 0 . DP=22;ADF=9,0;ADR=12,0;AD=21,0;I16=9,12,0,0,798,30664,0,0,989,51297,0,0,392,8620,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,36,255:12:0:7,0:5,0:12,0 0,12,95:4:0:0,0:4,0:4,0 0,15,161:5:0:2,0:3,0:5,0 +17 274 . C <*> 0 . DP=22;ADF=9,0;ADR=12,0;AD=21,0;I16=9,12,0,0,763,28177,0,0,989,51297,0,0,394,8746,0,0;QS=3,0;MQSB=0.0158903;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,36,255:12:0:7,0:5,0:12,0 0,12,101:4:0:0,0:4,0:4,0 0,15,144:5:0:2,0:3,0:5,0 +17 275 . C <*> 0 . DP=20;ADF=7,0;ADR=13,0;AD=20,0;I16=7,13,0,0,768,29994,0,0,898,44938,0,0,423,9519,0,0;QS=3,0;MQSB=0.0213617;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:6,0:5,0:11,0 0,15,114:5:0:0,0:5,0:5,0 0,12,122:4:0:1,0:3,0:4,0 +17 276 . A <*> 0 . DP=20;ADF=7,0;ADR=13,0;AD=20,0;I16=7,13,0,0,805,32931,0,0,898,44938,0,0,424,9538,0,0;QS=3,0;MQSB=0.0213617;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,253:11:0:6,0:5,0:11,0 0,15,122:5:0:0,0:5,0:5,0 0,12,124:4:0:1,0:3,0:4,0 +17 277 . G <*> 0 . DP=20;ADF=7,0;ADR=13,0;AD=20,0;I16=7,13,0,0,764,29732,0,0,898,44938,0,0,425,9579,0,0;QS=3,0;MQSB=0.0213617;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:6,0:5,0:11,0 0,15,114:5:0:0,0:5,0:5,0 0,12,121:4:0:1,0:3,0:4,0 +17 278 . A <*> 0 . DP=21;ADF=6,0;ADR=14,0;AD=20,0;I16=6,14,0,0,722,26452,0,0,867,42179,0,0,415,9521,0,0;QS=3,0;MQSB=0.0246228;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,238:10:0:5,0:5,0:10,0 0,18,123:6:0:0,0:6,0:6,0 0,12,121:4:0:1,0:3,0:4,0 +17 279 . A <*> 0 . DP=22;ADF=7,0;ADR=15,0;AD=22,0;I16=7,15,0,0,786,28694,0,0,956,46620,0,0,427,9677,0,0;QS=3,0;MQSB=0.0124927;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,36,255:12:0:6,0:6,0:12,0 0,18,123:6:0:0,0:6,0:6,0 0,12,122:4:0:1,0:3,0:4,0 +17 280 . A <*> 0 . DP=22;ADF=7,0;ADR=15,0;AD=22,0;I16=7,15,0,0,815,31561,0,0,956,46620,0,0,428,9684,0,0;QS=3,0;MQSB=0.0124927;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,36,253:12:0:6,0:6,0:12,0 0,18,130:6:0:0,0:6,0:6,0 0,12,129:4:0:1,0:3,0:4,0 +17 281 . G <*> 0 . DP=22;ADF=7,0;ADR=15,0;AD=22,0;I16=7,15,0,0,820,31416,0,0,956,46620,0,0,428,9662,0,0;QS=3,0;MQSB=0.0124927;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,36,255:12:0:6,0:6,0:12,0 0,18,122:6:0:0,0:6,0:6,0 0,12,123:4:0:1,0:3,0:4,0 +17 282 . G <*> 0 . DP=22;ADF=7,0;ADR=15,0;AD=22,0;I16=7,15,0,0,806,30420,0,0,956,46620,0,0,427,9609,0,0;QS=3,0;MQSB=0.0124927;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,36,253:12:0:6,0:6,0:12,0 0,18,124:6:0:0,0:6,0:6,0 0,12,119:4:0:1,0:3,0:4,0 +17 283 . C <*> 0 . DP=23;ADF=7,0;ADR=15,0;AD=22,0;I16=7,15,0,0,827,31785,0,0,956,46620,0,0,426,9574,0,0;QS=3,0;MQSB=0.0124927;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,36,255:12:0:6,0:6,0:12,0 0,18,125:6:0:0,0:6,0:6,0 0,12,122:4:0:1,0:3,0:4,0 +17 284 . T <*> 0 . DP=23;ADF=7,0;ADR=16,0;AD=23,0;I16=7,16,0,0,901,35479,0,0,1016,50220,0,0,431,9593,0,0;QS=3,0;MQSB=0.0194969;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,36,255:12:0:6,0:6,0:12,0 0,18,126:6:0:0,0:6,0:6,0 0,15,144:5:0:1,0:4,0:5,0 +17 285 . G <*> 0 . DP=23;ADF=7,0;ADR=16,0;AD=23,0;I16=7,16,0,0,860,32856,0,0,1016,50220,0,0,431,9607,0,0;QS=3,0;MQSB=0.0194969;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,36,255:12:0:6,0:6,0:12,0 0,18,119:6:0:0,0:6,0:6,0 0,15,132:5:0:1,0:4,0:5,0 +17 286 . C <*> 0 . DP=24;ADF=8,0;ADR=16,0;AD=24,0;I16=8,16,0,0,875,32883,0,0,1076,53820,0,0,431,9641,0,0;QS=3,0;MQSB=0.0132999;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,36,255:12:0:6,0:6,0:12,0 0,21,150:7:0:1,0:6,0:7,0 0,15,134:5:0:1,0:4,0:5,0 +17 287 . A <*> 0 . DP=25;ADF=9,0;ADR=16,0;AD=25,0;I16=9,16,0,0,895,32957,0,0,1136,57420,0,0,432,9696,0,0;QS=3,0;MQSB=0.00934348;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,36,255:12:0:6,0:6,0:12,0 0,24,178:8:0:2,0:6,0:8,0 0,15,133:5:0:1,0:4,0:5,0 +17 288 . T <*> 0 . DP=25;ADF=9,0;ADR=16,0;AD=25,0;I16=9,16,0,0,931,35011,0,0,1136,57420,0,0,432,9674,0,0;QS=3,0;MQSB=0.00934348;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,36,255:12:0:6,0:6,0:12,0 0,24,184:8:0:2,0:6,0:8,0 0,15,146:5:0:1,0:4,0:5,0 +17 289 . G <*> 0 . DP=25;ADF=9,0;ADR=16,0;AD=25,0;I16=9,16,0,0,939,36117,0,0,1136,57420,0,0,432,9676,0,0;QS=3,0;MQSB=0.00934348;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,36,255:12:0:6,0:6,0:12,0 0,24,185:8:0:2,0:6,0:8,0 0,15,136:5:0:1,0:4,0:5,0 +17 290 . G <*> 0 . DP=23;ADF=8,0;ADR=15,0;AD=23,0;I16=8,15,0,0,805,29157,0,0,1047,52979,0,0,433,9651,0,0;QS=3,0;MQSB=0.0177152;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,240:11:0:5,0:6,0:11,0 0,21,164:7:0:2,0:5,0:7,0 0,15,126:5:0:1,0:4,0:5,0 +17 291 . T <*> 0 . DP=24;ADF=8,0;ADR=15,0;AD=23,0;I16=8,15,0,0,840,31616,0,0,1047,52979,0,0,421,9479,0,0;QS=3,0;MQSB=0.0177152;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,244:11:0:5,0:6,0:11,0 0,21,168:7:0:2,0:5,0:7,0 0,15,136:5:0:1,0:4,0:5,0 +17 292 . T <*> 0 . DP=25;ADF=9,0;ADR=16,0;AD=25,0;I16=9,16,0,0,888,32274,0,0,1167,60179,0,0,436,9668,0,0;QS=3,0;MQSB=0.0197089;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,253:11:0:5,0:6,0:11,0 0,24,181:8:0:3,0:5,0:8,0 0,18,156:6:0:1,0:5,0:6,0 +17 293 . G <*> 0 . DP=26;ADF=10,0;ADR=15,0;AD=25,0;I16=10,15,0,0,934,35232,0,0,1167,60179,0,0,424,9488,0,0;QS=3,0;MQSB=0.0095249;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,36,255:12:0:6,0:6,0:12,0 0,24,196:8:0:3,0:5,0:8,0 0,15,145:5:0:1,0:4,0:5,0 +17 294 . A <*> 0 . DP=26;ADF=10,0;ADR=16,0;AD=26,0;I16=10,16,0,0,931,33937,0,0,1227,63779,0,0,443,9785,0,0;QS=3,0;MQSB=0.0149748;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,36,252:12:0:6,0:6,0:12,0 0,24,201:8:0:3,0:5,0:8,0 0,18,161:6:0:1,0:5,0:6,0 +17 295 . C <*> 0 . DP=25;ADF=10,0;ADR=14,0;AD=24,0;I16=10,14,0,0,897,33973,0,0,1169,62097,0,0,430,9544,0,0;QS=3,0;MQSB=0.0310726;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:6,0:5,0:11,0 0,21,180:7:0:3,0:4,0:7,0 0,18,159:6:0:1,0:5,0:6,0 +17 296 . A <*> 0 . DP=25;ADF=10,0;ADR=15,0;AD=25,0;I16=10,15,0,0,874,31846,0,0,1198,62938,0,0,451,9905,0,0;QS=3,0;MQSB=0.0213617;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:6,0:5,0:11,0 0,24,169:8:0:3,0:5,0:8,0 0,18,169:6:0:1,0:5,0:6,0 +17 297 . C <*> 0 . DP=25;ADF=9,0;ADR=15,0;AD=24,0;I16=9,15,0,0,901,34305,0,0,1138,59338,0,0,445,9901,0,0;QS=3,0;MQSB=0.0273237;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:6,0:5,0:11,0 0,21,174:7:0:2,0:5,0:7,0 0,18,161:6:0:1,0:5,0:6,0 +17 298 . A <*> 0 . DP=26;ADF=11,0;ADR=15,0;AD=26,0;I16=11,15,0,0,936,34652,0,0,1258,66538,0,0,459,10121,0,0;QS=3,0;MQSB=0.017008;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:6,0:5,0:11,0 0,24,184:8:0:3,0:5,0:8,0 0,21,191:7:0:2,0:5,0:7,0 +17 299 . C <*> 0 . DP=27;ADF=11,0;ADR=15,0;AD=26,0;I16=11,15,0,0,971,36863,0,0,1258,66538,0,0,464,10266,0,0;QS=3,0;MQSB=0.017008;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:6,0:5,0:11,0 0,24,193:8:0:3,0:5,0:8,0 0,21,189:7:0:2,0:5,0:7,0 +17 300 . A <*> 0 . DP=27;ADF=11,0;ADR=15,0;AD=26,0;I16=11,15,0,0,1001,39455,0,0,1258,66538,0,0,469,10437,0,0;QS=3,0;MQSB=0.017008;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:6,0:5,0:11,0 0,24,204:8:0:3,0:5,0:8,0 0,21,210:7:0:2,0:5,0:7,0 +17 301 . G <*> 0 . DP=25;ADF=10,0;ADR=14,0;AD=24,0;I16=10,14,0,0,928,36116,0,0,1169,62097,0,0,476,10632,0,0;QS=3,0;MQSB=0.0310726;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,255:10:0:5,0:5,0:10,0 0,21,195:7:0:3,0:4,0:7,0 0,21,196:7:0:2,0:5,0:7,0 +17 302 . T <*> 0 . DP=25;ADF=10,0;ADR=14,0;AD=24,0;I16=10,14,0,0,879,32885,0,0,1169,62097,0,0,483,10849,0,0;QS=3,0;MQSB=0.0310726;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,231:10:0:5,0:5,0:10,0 0,21,172:7:0:3,0:4,0:7,0 0,21,202:7:0:2,0:5,0:7,0 +17 302 . T TA 0 . INDEL;IDV=7;IMF=1;DP=25;ADF=2,8;ADR=4,11;AD=6,19;I16=2,4,8,11,214,7674,793,33369,236,10564,993,55133,109,2229,377,8629;QS=0.511212,2.48879;VDB=0.27613;SGB=-4.22417;MQSB=0.0443614;MQ0F=0 PL:DP:SP:ADF:ADR:AD 167,0,96:11:6:1,4:4,2:5,6 157,0,9:7:0:1,2:0,4:1,6 201,21,0:7:0:0,2:0,5:0,7 +17 303 . G <*> 0 . DP=25;ADF=10,0;ADR=15,0;AD=25,0;I16=10,15,0,0,976,38516,0,0,1229,65697,0,0,497,11181,0,0;QS=3,0;MQSB=0.0443614;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:5,0:6,0:11,0 0,21,197:7:0:3,0:4,0:7,0 0,21,195:7:0:2,0:5,0:7,0 +17 304 . C <*> 0 . DP=27;ADF=11,0;ADR=16,0;AD=27,0;I16=11,16,0,0,991,37005,0,0,1318,70138,0,0,503,11359,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:5,0:6,0:11,0 0,24,206:8:0:4,0:4,0:8,0 0,24,200:8:0:2,0:6,0:8,0 +17 305 . C <*> 0 . DP=27;ADF=11,0;ADR=16,0;AD=27,0;I16=11,16,0,0,1057,41761,0,0,1318,70138,0,0,510,11508,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:5,0:6,0:11,0 0,24,213:8:0:4,0:4,0:8,0 0,24,211:8:0:2,0:6,0:8,0 +17 306 . T <*> 0 . DP=27;ADF=11,0;ADR=16,0;AD=27,0;I16=11,16,0,0,1033,40253,0,0,1318,70138,0,0,517,11679,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:5,0:6,0:11,0 0,24,207:8:0:4,0:4,0:8,0 0,24,217:8:0:2,0:6,0:8,0 +17 307 . G <*> 0 . DP=27;ADF=11,0;ADR=15,0;AD=26,0;I16=11,15,0,0,984,37886,0,0,1289,69297,0,0,498,11198,0,0;QS=3,0;MQSB=0.174566;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:5,0:6,0:11,0 0,21,189:7:0:4,0:3,0:7,0 0,24,203:8:0:2,0:6,0:8,0 +17 308 . C <*> 0 . DP=27;ADF=11,0;ADR=16,0;AD=27,0;I16=11,16,0,0,892,30810,0,0,1318,70138,0,0,529,11991,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:5,0:6,0:11,0 0,24,178:8:0:4,0:4,0:8,0 0,24,185:8:0:2,0:6,0:8,0 +17 309 . G <*> 0 . DP=27;ADF=11,0;ADR=16,0;AD=27,0;I16=11,16,0,0,951,34599,0,0,1318,70138,0,0,535,12183,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,243:11:0:5,0:6,0:11,0 0,24,183:8:0:4,0:4,0:8,0 0,24,205:8:0:2,0:6,0:8,0 +17 310 . A <*> 0 . DP=27;ADF=11,0;ADR=16,0;AD=27,0;I16=11,16,0,0,1001,38063,0,0,1318,70138,0,0,540,12350,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:5,0:6,0:11,0 0,24,200:8:0:4,0:4,0:8,0 0,24,217:8:0:2,0:6,0:8,0 +17 311 . C <*> 0 . DP=27;ADF=11,0;ADR=16,0;AD=27,0;I16=11,16,0,0,1037,40263,0,0,1318,70138,0,0,544,12492,0,0;QS=3,0;MQSB=0.129164;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:5,0:6,0:11,0 0,24,215:8:0:4,0:4,0:8,0 0,24,210:8:0:2,0:6,0:8,0 +17 312 . A <*> 0 . DP=26;ADF=10,0;ADR=16,0;AD=26,0;I16=10,16,0,0,985,38043,0,0,1258,66538,0,0,549,12657,0,0;QS=3,0;MQSB=0.157183;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,237:10:0:4,0:6,0:10,0 0,24,215:8:0:4,0:4,0:8,0 0,24,218:8:0:2,0:6,0:8,0 +17 313 . A <*> 0 . DP=26;ADF=10,0;ADR=16,0;AD=26,0;I16=10,16,0,0,983,37969,0,0,1258,66538,0,0,551,12695,0,0;QS=3,0;MQSB=0.157183;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,235:10:0:4,0:6,0:10,0 0,24,219:8:0:4,0:4,0:8,0 0,24,215:8:0:2,0:6,0:8,0 +17 314 . A <*> 0 . DP=27;ADF=10,0;ADR=17,0;AD=27,0;I16=10,17,0,0,1050,41798,0,0,1318,70138,0,0,553,12757,0,0;QS=3,0;MQSB=0.195223;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,250:11:0:4,0:7,0:11,0 0,24,217:8:0:4,0:4,0:8,0 0,24,227:8:0:2,0:6,0:8,0 +17 315 . G <*> 0 . DP=26;ADF=10,0;ADR=16,0;AD=26,0;I16=10,16,0,0,1025,40941,0,0,1289,69297,0,0,557,12843,0,0;QS=3,0;MQSB=0.252051;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,252:10:0:4,0:6,0:10,0 0,24,216:8:0:4,0:4,0:8,0 0,24,225:8:0:2,0:6,0:8,0 +17 316 . C <*> 0 . DP=27;ADF=10,0;ADR=15,0;AD=25,0;I16=10,15,0,0,983,39393,0,0,1252,67928,0,0,535,12277,0,0;QS=3,0;MQSB=0.312403;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,255:10:0:4,0:6,0:10,0 0,21,183:7:0:4,0:3,0:7,0 0,24,224:8:0:2,0:6,0:8,0 +17 317 . T <*> 0 . DP=27;ADF=10,0;ADR=16,0;AD=26,0;I16=10,16,0,0,1028,41392,0,0,1320,72056,0,0,547,12557,0,0;QS=3,0;MQSB=0.377061;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,255:10:0:4,0:6,0:10,0 0,24,230:8:0:4,0:4,0:8,0 0,24,206:8:0:2,0:6,0:8,0 +17 318 . G <*> 0 . DP=27;ADF=10,0;ADR=17,0;AD=27,0;I16=10,17,0,0,1038,40546,0,0,1349,72897,0,0,570,13018,0,0;QS=3,0;MQSB=0.297797;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,249:10:0:4,0:6,0:10,0 0,27,235:9:0:4,0:5,0:9,0 0,24,208:8:0:2,0:6,0:8,0 +17 319 . A <*> 0 . DP=27;ADF=9,0;ADR=17,0;AD=26,0;I16=9,17,0,0,994,38654,0,0,1289,69297,0,0,560,12906,0,0;QS=3,0;MQSB=0.346864;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,249:10:0:4,0:6,0:10,0 0,27,228:9:0:4,0:5,0:9,0 0,21,185:7:0:1,0:6,0:7,0 +17 320 . A <*> 0 . DP=27;ADF=10,0;ADR=17,0;AD=27,0;I16=10,17,0,0,1022,39418,0,0,1349,72897,0,0,573,13053,0,0;QS=3,0;MQSB=0.297797;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,247:10:0:4,0:6,0:10,0 0,27,230:9:0:4,0:5,0:9,0 0,24,211:8:0:2,0:6,0:8,0 +17 321 . T <*> 0 . DP=27;ADF=10,0;ADR=17,0;AD=27,0;I16=10,17,0,0,1026,39772,0,0,1349,72897,0,0,573,13029,0,0;QS=3,0;MQSB=0.297797;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,253:10:0:4,0:6,0:10,0 0,27,214:9:0:4,0:5,0:9,0 0,24,218:8:0:2,0:6,0:8,0 +17 322 . G <*> 0 . DP=28;ADF=10,0;ADR=18,0;AD=28,0;I16=10,18,0,0,1091,43151,0,0,1409,76497,0,0,573,13029,0,0;QS=3,0;MQSB=0.343265;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,255:10:0:4,0:6,0:10,0 0,27,226:9:0:4,0:5,0:9,0 0,27,223:9:0:2,0:7,0:9,0 +17 323 . C <*> 0 . DP=28;ADF=9,0;ADR=18,0;AD=27,0;I16=9,18,0,0,1067,42619,0,0,1349,72897,0,0,565,12939,0,0;QS=3,0;MQSB=0.394987;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,255:10:0:4,0:6,0:10,0 0,27,225:9:0:4,0:5,0:9,0 0,24,198:8:0:1,0:7,0:8,0 +17 324 . T <*> 0 . DP=30;ADF=12,0;ADR=18,0;AD=30,0;I16=12,18,0,0,1145,44221,0,0,1529,83697,0,0,573,13001,0,0;QS=3,0;MQSB=0.264959;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,253:10:0:4,0:6,0:10,0 0,27,237:9:0:4,0:5,0:9,0 0,33,255:11:0:4,0:7,0:11,0 +17 325 . A <*> 0 . DP=31;ADF=13,0;ADR=18,0;AD=31,0;I16=13,18,0,0,1132,42058,0,0,1589,87297,0,0,573,12925,0,0;QS=3,0;MQSB=0.235201;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:5,0:6,0:11,0 0,27,208:9:0:4,0:5,0:9,0 0,33,255:11:0:4,0:7,0:11,0 +17 326 . T <*> 0 . DP=31;ADF=13,0;ADR=18,0;AD=31,0;I16=13,18,0,0,1157,44193,0,0,1589,87297,0,0,574,12878,0,0;QS=3,0;MQSB=0.235201;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:5,0:6,0:11,0 0,27,216:9:0:4,0:5,0:9,0 0,33,255:11:0:4,0:7,0:11,0 +17 327 . C <*> 0 . DP=31;ADF=13,0;ADR=18,0;AD=31,0;I16=13,18,0,0,1147,43895,0,0,1589,87297,0,0,575,12861,0,0;QS=3,0;MQSB=0.235201;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:5,0:6,0:11,0 0,27,198:9:0:4,0:5,0:9,0 0,33,255:11:0:4,0:7,0:11,0 +17 328 . A <*> 0 . DP=31;ADF=13,0;ADR=18,0;AD=31,0;I16=13,18,0,0,1167,44531,0,0,1589,87297,0,0,574,12776,0,0;QS=3,0;MQSB=0.235201;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:5,0:6,0:11,0 0,27,226:9:0:4,0:5,0:9,0 0,33,255:11:0:4,0:7,0:11,0 +17 329 . T <*> 0 . DP=31;ADF=13,0;ADR=18,0;AD=31,0;I16=13,18,0,0,1210,47742,0,0,1589,87297,0,0,572,12676,0,0;QS=3,0;MQSB=0.235201;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:5,0:6,0:11,0 0,27,237:9:0:4,0:5,0:9,0 0,33,255:11:0:4,0:7,0:11,0 +17 330 . T <*> 0 . DP=31;ADF=13,0;ADR=18,0;AD=31,0;I16=13,18,0,0,1185,45839,0,0,1589,87297,0,0,568,12510,0,0;QS=3,0;MQSB=0.235201;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,254:11:0:5,0:6,0:11,0 0,27,231:9:0:4,0:5,0:9,0 0,33,255:11:0:4,0:7,0:11,0 +17 331 . T <*> 0 . DP=32;ADF=14,0;ADR=18,0;AD=32,0;I16=14,18,0,0,1154,42510,0,0,1649,90897,0,0,563,12327,0,0;QS=3,0;MQSB=0.210122;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:5,0:6,0:11,0 0,27,222:9:0:4,0:5,0:9,0 0,36,255:12:0:5,0:7,0:12,0 +17 332 . A <*> 0 . DP=32;ADF=14,0;ADR=18,0;AD=32,0;I16=14,18,0,0,1156,42666,0,0,1649,90897,0,0,560,12178,0,0;QS=3,0;MQSB=0.210122;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,36,255:12:0:6,0:6,0:12,0 0,27,214:9:0:4,0:5,0:9,0 0,33,255:11:0:4,0:7,0:11,0 +17 333 . A <*> 0 . DP=32;ADF=14,0;ADR=18,0;AD=32,0;I16=14,18,0,0,1141,41987,0,0,1649,90897,0,0,558,12064,0,0;QS=3,0;MQSB=0.210122;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,36,255:12:0:6,0:6,0:12,0 0,27,223:9:0:4,0:5,0:9,0 0,33,255:11:0:4,0:7,0:11,0 +17 334 . A <*> 0 . DP=32;ADF=14,0;ADR=18,0;AD=32,0;I16=14,18,0,0,1162,43328,0,0,1649,90897,0,0,556,11986,0,0;QS=3,0;MQSB=0.210122;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,36,255:12:0:6,0:6,0:12,0 0,27,221:9:0:4,0:5,0:9,0 0,33,255:11:0:4,0:7,0:11,0 +17 335 . A <*> 0 . DP=32;ADF=12,0;ADR=18,0;AD=30,0;I16=12,18,0,0,1077,40287,0,0,1529,83697,0,0,552,11934,0,0;QS=3,0;MQSB=0.264959;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,250:10:0:4,0:6,0:10,0 0,27,219:9:0:4,0:5,0:9,0 0,33,251:11:0:4,0:7,0:11,0 +17 336 . A <*> 0 . DP=32;ADF=14,0;ADR=17,0;AD=31,0;I16=14,17,0,0,1088,39758,0,0,1612,89528,0,0,536,11574,0,0;QS=3,0;MQSB=0.274662;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:5,0:6,0:11,0 0,24,211:8:0:4,0:4,0:8,0 0,36,255:12:0:5,0:7,0:12,0 +17 337 . C <*> 0 . DP=32;ADF=13,0;ADR=17,0;AD=30,0;I16=13,17,0,0,1115,42381,0,0,1552,85928,0,0,531,11565,0,0;QS=3,0;MQSB=0.301511;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,255:10:0:4,0:6,0:10,0 0,24,202:8:0:4,0:4,0:8,0 0,36,255:12:0:5,0:7,0:12,0 +17 338 . T <*> 0 . DP=30;ADF=14,0;ADR=16,0;AD=30,0;I16=14,16,0,0,1191,47979,0,0,1560,86456,0,0,554,11878,0,0;QS=3,0;MQSB=0.242376;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,255:10:0:5,0:5,0:10,0 0,24,226:8:0:4,0:4,0:8,0 0,36,255:12:0:5,0:7,0:12,0 +17 339 . C <*> 0 . DP=31;ADF=14,0;ADR=17,0;AD=31,0;I16=14,17,0,0,1130,43210,0,0,1589,87297,0,0,554,11874,0,0;QS=3,0;MQSB=0.175471;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:5,0:6,0:11,0 0,24,185:8:0:4,0:4,0:8,0 0,36,255:12:0:5,0:7,0:12,0 +17 340 . C <*> 0 . DP=31;ADF=14,0;ADR=17,0;AD=31,0;I16=14,17,0,0,1196,47044,0,0,1589,87297,0,0,554,11852,0,0;QS=3,0;MQSB=0.175471;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:5,0:6,0:11,0 0,24,221:8:0:4,0:4,0:8,0 0,36,255:12:0:5,0:7,0:12,0 +17 341 . T <*> 0 . DP=31;ADF=14,0;ADR=17,0;AD=31,0;I16=14,17,0,0,1227,48995,0,0,1589,87297,0,0,554,11862,0,0;QS=3,0;MQSB=0.175471;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:5,0:6,0:11,0 0,24,216:8:0:4,0:4,0:8,0 0,36,255:12:0:5,0:7,0:12,0 +17 342 . T <*> 0 . DP=31;ADF=14,0;ADR=17,0;AD=31,0;I16=14,17,0,0,1162,43942,0,0,1589,87297,0,0,554,11904,0,0;QS=3,0;MQSB=0.175471;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:5,0:6,0:11,0 0,24,210:8:0:4,0:4,0:8,0 0,36,255:12:0:5,0:7,0:12,0 +17 343 . G <*> 0 . DP=32;ADF=14,0;ADR=17,0;AD=31,0;I16=14,17,0,0,1150,43702,0,0,1620,90056,0,0,550,11962,0,0;QS=3,0;MQSB=0.283511;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,249:10:0:5,0:5,0:10,0 0,27,218:9:0:4,0:5,0:9,0 0,36,255:12:0:5,0:7,0:12,0 +17 344 . C <*> 0 . DP=32;ADF=14,0;ADR=18,0;AD=32,0;I16=14,18,0,0,1181,45169,0,0,1649,90897,0,0,554,12036,0,0;QS=3,0;MQSB=0.210122;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:5,0:6,0:11,0 0,27,217:9:0:4,0:5,0:9,0 0,36,255:12:0:5,0:7,0:12,0 +17 345 . T <*> 0 . DP=31;ADF=14,0;ADR=17,0;AD=31,0;I16=14,17,0,0,1205,47259,0,0,1589,87297,0,0,555,12129,0,0;QS=3,0;MQSB=0.175471;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:5,0:6,0:11,0 0,24,221:8:0:4,0:4,0:8,0 0,36,255:12:0:5,0:7,0:12,0 +17 346 . G <*> 0 . DP=31;ADF=15,0;ADR=16,0;AD=31,0;I16=15,16,0,0,1147,43597,0,0,1620,90056,0,0,557,12255,0,0;QS=3,0;MQSB=0.220358;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:6,0:5,0:11,0 0,24,212:8:0:4,0:4,0:8,0 0,36,255:12:0:5,0:7,0:12,0 +17 347 . G <*> 0 . DP=31;ADF=14,0;ADR=16,0;AD=30,0;I16=14,16,0,0,1119,42227,0,0,1560,86456,0,0,545,12189,0,0;QS=3,0;MQSB=0.242376;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,251:10:0:5,0:5,0:10,0 0,24,207:8:0:4,0:4,0:8,0 0,36,255:12:0:5,0:7,0:12,0 +17 348 . T <*> 0 . DP=32;ADF=15,0;ADR=16,0;AD=31,0;I16=15,16,0,0,1145,43007,0,0,1620,90056,0,0,546,12300,0,0;QS=3,0;MQSB=0.220358;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,243:10:0:5,0:5,0:10,0 0,27,228:9:0:5,0:4,0:9,0 0,36,255:12:0:5,0:7,0:12,0 +17 349 . T <*> 0 . DP=32;ADF=16,0;ADR=16,0;AD=32,0;I16=16,16,0,0,1194,45350,0,0,1680,93656,0,0,565,12731,0,0;QS=3,0;MQSB=0.201402;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,246:11:0:6,0:5,0:11,0 0,27,230:9:0:5,0:4,0:9,0 0,36,255:12:0:5,0:7,0:12,0 +17 350 . T <*> 0 . DP=31;ADF=16,0;ADR=15,0;AD=31,0;I16=16,15,0,0,1142,43072,0,0,1651,92815,0,0,567,12837,0,0;QS=3,0;MQSB=0.286505;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,249:11:0:6,0:5,0:11,0 0,27,230:9:0:5,0:4,0:9,0 0,33,255:11:0:5,0:6,0:11,0 +17 351 . G <*> 0 . DP=31;ADF=16,0;ADR=15,0;AD=31,0;I16=16,15,0,0,1146,43750,0,0,1651,92815,0,0,568,12920,0,0;QS=3,0;MQSB=0.286505;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:6,0:5,0:11,0 0,27,212:9:0:5,0:4,0:9,0 0,33,255:11:0:5,0:6,0:11,0 +17 352 . A <*> 0 . DP=31;ADF=16,0;ADR=14,0;AD=30,0;I16=16,14,0,0,1150,45520,0,0,1591,89215,0,0,544,12404,0,0;QS=3,0;MQSB=0.242376;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:6,0:5,0:11,0 0,24,224:8:0:5,0:3,0:8,0 0,33,255:11:0:5,0:6,0:11,0 +17 353 . G <*> 0 . DP=29;ADF=15,0;ADR=14,0;AD=29,0;I16=15,14,0,0,1109,43095,0,0,1562,88374,0,0,570,13064,0,0;QS=3,0;MQSB=0.424373;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,255:10:0:5,0:5,0:10,0 0,27,231:9:0:5,0:4,0:9,0 0,30,255:10:0:5,0:5,0:10,0 +17 354 . A <*> 0 . DP=28;ADF=14,0;ADR=14,0;AD=28,0;I16=14,14,0,0,1078,42938,0,0,1502,84774,0,0,571,13075,0,0;QS=3,0;MQSB=0.450096;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,27,225:9:0:4,0:5,0:9,0 0,27,244:9:0:5,0:4,0:9,0 0,30,255:10:0:5,0:5,0:10,0 +17 355 . G T,<*> 0 . DP=28;ADF=14,0,0;ADR=13,1,0;AD=27,1,0;I16=14,13,0,1,1001,37907,41,1681,1442,81174,60,3600,547,12487,25,625;QS=2.875,0.125,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.450096;BQB=1;MQ0F=0 PL:DP:SP:ADF:ADR:AD 14,0,200,38,203,231:9:0:4,0,0:4,1,0:8,1,0 0,27,222,27,222,222:9:0:5,0,0:4,0,0:9,0,0 0,30,255,30,255,255:10:0:5,0,0:5,0,0:10,0,0 +17 356 . G <*> 0 . DP=27;ADF=14,0;ADR=13,0;AD=27,0;I16=14,13,0,0,993,37481,0,0,1465,83405,0,0,574,13174,0,0;QS=3,0;MQSB=0.580277;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,27,228:9:0:4,0:5,0:9,0 0,24,201:8:0:5,0:3,0:8,0 0,30,255:10:0:5,0:5,0:10,0 +17 357 . C <*> 0 . DP=28;ADF=14,0;ADR=13,0;AD=27,0;I16=14,13,0,0,1021,39471,0,0,1465,83405,0,0,550,12584,0,0;QS=3,0;MQSB=0.580277;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,255:10:0:5,0:5,0:10,0 0,24,205:8:0:5,0:3,0:8,0 0,27,251:9:0:4,0:5,0:9,0 +17 358 . A <*> 0 . DP=28;ADF=15,0;ADR=13,0;AD=28,0;I16=15,13,0,0,1050,40518,0,0,1525,87005,0,0,576,13216,0,0;QS=3,0;MQSB=0.556581;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,254:10:0:5,0:5,0:10,0 0,24,197:8:0:5,0:3,0:8,0 0,30,255:10:0:5,0:5,0:10,0 +17 359 . G <*> 0 . DP=29;ADF=15,0;ADR=13,0;AD=28,0;I16=15,13,0,0,1085,42761,0,0,1525,87005,0,0,552,12620,0,0;QS=3,0;MQSB=0.556581;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,255:10:0:5,0:5,0:10,0 0,21,187:7:0:5,0:2,0:7,0 0,33,255:11:0:5,0:6,0:11,0 +17 360 . A <*> 0 . DP=29;ADF=15,0;ADR=14,0;AD=29,0;I16=15,14,0,0,1111,43259,0,0,1585,90605,0,0,579,13297,0,0;QS=3,0;MQSB=0.604224;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,252:10:0:5,0:5,0:10,0 0,24,220:8:0:5,0:3,0:8,0 0,33,255:11:0:5,0:6,0:11,0 +17 361 . A <*> 0 . DP=29;ADF=15,0;ADR=14,0;AD=29,0;I16=15,14,0,0,1116,43442,0,0,1585,90605,0,0,579,13273,0,0;QS=3,0;MQSB=0.604224;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,252:10:0:5,0:5,0:10,0 0,24,219:8:0:5,0:3,0:8,0 0,33,255:11:0:5,0:6,0:11,0 +17 362 . A <*> 0 . DP=29;ADF=16,0;ADR=13,0;AD=29,0;I16=16,13,0,0,1104,42700,0,0,1585,90605,0,0,580,13272,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:6,0:5,0:11,0 0,24,218:8:0:5,0:3,0:8,0 0,30,255:10:0:5,0:5,0:10,0 +17 363 . A <*> 0 . DP=29;ADF=16,0;ADR=13,0;AD=29,0;I16=16,13,0,0,1087,41437,0,0,1585,90605,0,0,581,13245,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:6,0:5,0:11,0 0,24,213:8:0:5,0:3,0:8,0 0,30,255:10:0:5,0:5,0:10,0 +17 364 . T <*> 0 . DP=29;ADF=16,0;ADR=13,0;AD=29,0;I16=16,13,0,0,1032,37960,0,0,1585,90605,0,0,582,13244,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,250:11:0:6,0:5,0:11,0 0,24,205:8:0:5,0:3,0:8,0 0,30,255:10:0:5,0:5,0:10,0 +17 365 . G <*> 0 . DP=29;ADF=16,0;ADR=13,0;AD=29,0;I16=16,13,0,0,1105,43079,0,0,1585,90605,0,0,582,13218,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:6,0:5,0:11,0 0,24,211:8:0:5,0:3,0:8,0 0,30,255:10:0:5,0:5,0:10,0 +17 366 . A <*> 0 . DP=29;ADF=16,0;ADR=13,0;AD=29,0;I16=16,13,0,0,1090,41562,0,0,1585,90605,0,0,581,13167,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:6,0:5,0:11,0 0,24,211:8:0:5,0:3,0:8,0 0,30,255:10:0:5,0:5,0:10,0 +17 367 . T <*> 0 . DP=29;ADF=16,0;ADR=13,0;AD=29,0;I16=16,13,0,0,1055,39149,0,0,1585,90605,0,0,579,13093,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:6,0:5,0:11,0 0,24,204:8:0:5,0:3,0:8,0 0,30,255:10:0:5,0:5,0:10,0 +17 368 . A <*> 0 . DP=29;ADF=16,0;ADR=13,0;AD=29,0;I16=16,13,0,0,1054,39632,0,0,1585,90605,0,0,576,12998,0,0;QS=3,0;MQSB=0.535133;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:6,0:5,0:11,0 0,24,208:8:0:5,0:3,0:8,0 0,30,255:10:0:5,0:5,0:10,0 +17 369 . T <*> 0 . DP=28;ADF=16,0;ADR=11,0;AD=27,0;I16=16,11,0,0,1037,40275,0,0,1496,86164,0,0,548,12256,0,0;QS=3,0;MQSB=0.659218;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,250:10:0:6,0:4,0:10,0 0,21,196:7:0:5,0:2,0:7,0 0,30,255:10:0:5,0:5,0:10,0 +17 370 . C <*> 0 . DP=28;ADF=16,0;ADR=12,0;AD=28,0;I16=16,12,0,0,1045,40219,0,0,1556,89764,0,0,570,12790,0,0;QS=3,0;MQSB=0.705296;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,255:10:0:6,0:4,0:10,0 0,24,201:8:0:5,0:3,0:8,0 0,30,255:10:0:5,0:5,0:10,0 +17 371 . T <*> 0 . DP=29;ADF=16,0;ADR=13,0;AD=29,0;I16=16,13,0,0,1155,46591,0,0,1616,93364,0,0,567,12725,0,0;QS=3,0;MQSB=0.744925;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,255:10:0:6,0:4,0:10,0 0,24,227:8:0:5,0:3,0:8,0 0,33,255:11:0:5,0:6,0:11,0 +17 372 . C <*> 0 . DP=30;ADF=16,0;ADR=14,0;AD=30,0;I16=16,14,0,0,1139,44019,0,0,1676,96964,0,0,564,12636,0,0;QS=3,0;MQSB=0.779025;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:6,0:5,0:11,0 0,24,215:8:0:5,0:3,0:8,0 0,33,255:11:0:5,0:6,0:11,0 +17 373 . A <*> 0 . DP=30;ADF=16,0;ADR=14,0;AD=30,0;I16=16,14,0,0,1142,44118,0,0,1676,96964,0,0,561,12525,0,0;QS=3,0;MQSB=0.779025;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:6,0:5,0:11,0 0,24,220:8:0:5,0:3,0:8,0 0,33,255:11:0:5,0:6,0:11,0 +17 374 . T <*> 0 . DP=30;ADF=16,0;ADR=14,0;AD=30,0;I16=16,14,0,0,1098,41180,0,0,1676,96964,0,0,556,12344,0,0;QS=3,0;MQSB=0.779025;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:6,0:5,0:11,0 0,24,221:8:0:5,0:3,0:8,0 0,33,255:11:0:5,0:6,0:11,0 +17 375 . A T,<*> 0 . DP=31;ADF=17,0,0;ADR=13,1,0;AD=30,1,0;I16=17,13,0,1,1138,43798,14,196,1676,96964,60,3600,547,12177,4,16;QS=2.9661,0.0338983,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.763662;BQB=1;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,36,255,36,255,255:12:0:7,0,0:5,0,0:12,0,0 0,24,218,24,218,218:8:0:5,0,0:3,0,0:8,0,0 0,18,255,30,255,255:11:0:5,0,0:5,1,0:10,1,0 +17 376 . G <*> 0 . DP=31;ADF=17,0;ADR=14,0;AD=31,0;I16=17,14,0,0,1131,42581,0,0,1736,100564,0,0,547,12073,0,0;QS=3,0;MQSB=0.763662;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,36,255:12:0:7,0:5,0:12,0 0,24,220:8:0:5,0:3,0:8,0 0,33,255:11:0:5,0:6,0:11,0 +17 377 . T <*> 0 . DP=31;ADF=16,0;ADR=14,0;AD=30,0;I16=16,14,0,0,1105,41629,0,0,1676,96964,0,0,518,11360,0,0;QS=3,0;MQSB=0.779025;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:6,0:5,0:11,0 0,24,211:8:0:5,0:3,0:8,0 0,33,255:11:0:5,0:6,0:11,0 +17 378 . T <*> 0 . DP=30;ADF=18,0;ADR=12,0;AD=30,0;I16=18,12,0,0,1098,41066,0,0,1707,99723,0,0,541,11927,0,0;QS=3,0;MQSB=0.878946;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,39,255:13:0:8,0:5,0:13,0 0,21,186:7:0:5,0:2,0:7,0 0,30,255:10:0:5,0:5,0:10,0 +17 379 . G <*> 0 . DP=29;ADF=18,0;ADR=10,0;AD=28,0;I16=18,10,0,0,1053,40181,0,0,1618,95282,0,0,534,11848,0,0;QS=3,0;MQSB=0.981777;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:8,0:3,0:11,0 0,21,187:7:0:5,0:2,0:7,0 0,30,255:10:0:5,0:5,0:10,0 +17 380 . C <*> 0 . DP=29;ADF=18,0;ADR=10,0;AD=28,0;I16=18,10,0,0,1087,42743,0,0,1618,95282,0,0,514,11172,0,0;QS=3,0;MQSB=0.981777;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,36,255:12:0:8,0:4,0:12,0 0,18,177:6:0:5,0:1,0:6,0 0,30,255:10:0:5,0:5,0:10,0 +17 381 . T <*> 0 . DP=29;ADF=18,0;ADR=11,0;AD=29,0;I16=18,11,0,0,1168,47412,0,0,1678,98882,0,0,537,11729,0,0;QS=3,0;MQSB=0.987702;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,36,255:12:0:8,0:4,0:12,0 0,21,212:7:0:5,0:2,0:7,0 0,30,255:10:0:5,0:5,0:10,0 +17 382 . T <*> 0 . DP=29;ADF=17,0;ADR=11,0;AD=28,0;I16=17,11,0,0,1054,40450,0,0,1618,95282,0,0,510,11068,0,0;QS=3,0;MQSB=0.990092;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,33,255:11:0:7,0:4,0:11,0 0,21,182:7:0:5,0:2,0:7,0 0,30,255:10:0:5,0:5,0:10,0 +17 383 . T <*> 0 . DP=29;ADF=18,0;ADR=10,0;AD=28,0;I16=18,10,0,0,1052,39798,0,0,1618,95282,0,0,507,11013,0,0;QS=3,0;MQSB=0.981777;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,36,255:12:0:8,0:4,0:12,0 0,18,165:6:0:5,0:1,0:6,0 0,30,255:10:0:5,0:5,0:10,0 +17 384 . A <*> 0 . DP=31;ADF=19,0;ADR=11,0;AD=30,0;I16=19,11,0,0,1077,39885,0,0,1738,102482,0,0,504,10988,0,0;QS=3,0;MQSB=0.985292;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,39,255:13:0:8,0:5,0:13,0 0,21,176:7:0:6,0:1,0:7,0 0,30,255:10:0:5,0:5,0:10,0 +17 385 . C <*> 0 . DP=31;ADF=19,0;ADR=12,0;AD=31,0;I16=19,12,0,0,1118,41180,0,0,1798,106082,0,0,527,11569,0,0;QS=3,0;MQSB=0.989977;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,39,255:13:0:8,0:5,0:13,0 0,24,186:8:0:6,0:2,0:8,0 0,30,255:10:0:5,0:5,0:10,0 +17 386 . T <*> 0 . DP=30;ADF=18,0;ADR=12,0;AD=30,0;I16=18,12,0,0,1158,45592,0,0,1738,102482,0,0,526,11556,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,39,255:13:0:8,0:5,0:13,0 0,21,191:7:0:5,0:2,0:7,0 0,30,255:10:0:5,0:5,0:10,0 +17 387 . T <*> 0 . DP=30;ADF=18,0;ADR=12,0;AD=30,0;I16=18,12,0,0,1105,41821,0,0,1738,102482,0,0,525,11573,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,39,255:13:0:8,0:5,0:13,0 0,21,187:7:0:5,0:2,0:7,0 0,30,255:10:0:5,0:5,0:10,0 +17 388 . T <*> 0 . DP=29;ADF=17,0;ADR=12,0;AD=29,0;I16=17,12,0,0,1089,41577,0,0,1678,98882,0,0,523,11519,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,39,255:13:0:8,0:5,0:13,0 0,18,180:6:0:4,0:2,0:6,0 0,30,255:10:0:5,0:5,0:10,0 +17 389 . G <*> 0 . DP=29;ADF=17,0;ADR=12,0;AD=29,0;I16=17,12,0,0,1067,40095,0,0,1678,98882,0,0,520,11444,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,39,255:13:0:8,0:5,0:13,0 0,18,171:6:0:4,0:2,0:6,0 0,30,255:10:0:5,0:5,0:10,0 +17 390 . C <*> 0 . DP=29;ADF=17,0;ADR=12,0;AD=29,0;I16=17,12,0,0,1071,40423,0,0,1678,98882,0,0,517,11399,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,39,255:13:0:8,0:5,0:13,0 0,18,162:6:0:4,0:2,0:6,0 0,30,255:10:0:5,0:5,0:10,0 +17 391 . A <*> 0 . DP=29;ADF=18,0;ADR=11,0;AD=29,0;I16=18,11,0,0,1091,41603,0,0,1647,96123,0,0,515,11383,0,0;QS=3,0;MQSB=0.995968;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,39,255:13:0:8,0:5,0:13,0 0,18,163:6:0:4,0:2,0:6,0 0,30,255:10:0:6,0:4,0:10,0 +17 392 . T <*> 0 . DP=29;ADF=18,0;ADR=11,0;AD=29,0;I16=18,11,0,0,1046,38838,0,0,1647,96123,0,0,515,11395,0,0;QS=3,0;MQSB=0.995968;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,39,255:13:0:8,0:5,0:13,0 0,15,153:5:0:3,0:2,0:5,0 0,33,255:11:0:7,0:4,0:11,0 +17 393 . A <*> 0 . DP=28;ADF=17,0;ADR=11,0;AD=28,0;I16=17,11,0,0,1014,37582,0,0,1587,92523,0,0,517,11435,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,36,255:12:0:7,0:5,0:12,0 0,15,133:5:0:3,0:2,0:5,0 0,33,255:11:0:7,0:4,0:11,0 +17 394 . T <*> 0 . DP=28;ADF=17,0;ADR=11,0;AD=28,0;I16=17,11,0,0,1022,38342,0,0,1587,92523,0,0,519,11503,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,36,255:12:0:7,0:5,0:12,0 0,15,141:5:0:3,0:2,0:5,0 0,33,255:11:0:7,0:4,0:11,0 +17 395 . T <*> 0 . DP=28;ADF=17,0;ADR=11,0;AD=28,0;I16=17,11,0,0,1060,40596,0,0,1587,92523,0,0,521,11599,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,36,255:12:0:7,0:5,0:12,0 0,15,164:5:0:3,0:2,0:5,0 0,33,255:11:0:7,0:4,0:11,0 +17 396 . T <*> 0 . DP=28;ADF=17,0;ADR=11,0;AD=28,0;I16=17,11,0,0,1032,39228,0,0,1587,92523,0,0,523,11723,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,36,255:12:0:7,0:5,0:12,0 0,15,158:5:0:3,0:2,0:5,0 0,33,255:11:0:7,0:4,0:11,0 +17 397 . T <*> 0 . DP=28;ADF=17,0;ADR=11,0;AD=28,0;I16=17,11,0,0,1046,39510,0,0,1587,92523,0,0,524,11824,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,36,255:12:0:7,0:5,0:12,0 0,15,149:5:0:3,0:2,0:5,0 0,33,255:11:0:7,0:4,0:11,0 +17 398 . A <*> 0 . DP=28;ADF=17,0;ADR=11,0;AD=28,0;I16=17,11,0,0,1021,38105,0,0,1587,92523,0,0,524,11850,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,39,255:13:0:8,0:5,0:13,0 0,15,144:5:0:3,0:2,0:5,0 0,30,255:10:0:6,0:4,0:10,0 +17 399 . A <*> 0 . DP=28;ADF=17,0;ADR=11,0;AD=28,0;I16=17,11,0,0,1015,38469,0,0,1587,92523,0,0,526,11900,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,39,255:13:0:8,0:5,0:13,0 0,15,140:5:0:3,0:2,0:5,0 0,30,255:10:0:6,0:4,0:10,0 +17 400 . A <*> 0 . DP=29;ADF=17,0;ADR=12,0;AD=29,0;I16=17,12,0,0,1056,39702,0,0,1647,96123,0,0,526,11828,0,0;QS=3,0;MQSB=0.988062;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,39,255:13:0:8,0:5,0:13,0 0,15,159:5:0:3,0:2,0:5,0 0,33,255:11:0:6,0:5,0:11,0 +17 401 . A <*> 0 . DP=29;ADF=17,0;ADR=11,0;AD=28,0;I16=17,11,0,0,1052,40302,0,0,1587,92523,0,0,501,11113,0,0;QS=3,0;MQSB=0.993109;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,39,255:13:0:8,0:5,0:13,0 0,15,160:5:0:3,0:2,0:5,0 0,30,255:10:0:6,0:4,0:10,0 +17 402 . T <*> 0 . DP=29;ADF=17,0;ADR=12,0;AD=29,0;I16=17,12,0,0,1082,41232,0,0,1647,96123,0,0,526,11680,0,0;QS=3,0;MQSB=0.988062;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,39,255:13:0:8,0:5,0:13,0 0,15,149:5:0:3,0:2,0:5,0 0,33,255:11:0:6,0:5,0:11,0 +17 403 . T <*> 0 . DP=29;ADF=17,0;ADR=12,0;AD=29,0;I16=17,12,0,0,1085,40985,0,0,1647,96123,0,0,526,11654,0,0;QS=3,0;MQSB=0.988062;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,39,255:13:0:8,0:5,0:13,0 0,15,148:5:0:3,0:2,0:5,0 0,33,255:11:0:6,0:5,0:11,0 +17 404 . G <*> 0 . DP=29;ADF=17,0;ADR=12,0;AD=29,0;I16=17,12,0,0,1074,40524,0,0,1647,96123,0,0,525,11609,0,0;QS=3,0;MQSB=0.988062;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,39,255:13:0:8,0:5,0:13,0 0,15,131:5:0:3,0:2,0:5,0 0,33,255:11:0:6,0:5,0:11,0 +17 405 . T <*> 0 . DP=27;ADF=16,0;ADR=10,0;AD=26,0;I16=16,10,0,0,988,37870,0,0,1498,88082,0,0,519,11543,0,0;QS=3,0;MQSB=0.987578;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,39,255:13:0:8,0:5,0:13,0 0,9,103:3:0:2,0:1,0:3,0 0,30,255:10:0:6,0:4,0:10,0 +17 406 . G <*> 0 . DP=27;ADF=16,0;ADR=11,0;AD=27,0;I16=16,11,0,0,976,36752,0,0,1558,91682,0,0,527,11601,0,0;QS=3,0;MQSB=0.992419;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,39,255:13:0:8,0:5,0:13,0 0,12,125:4:0:2,0:2,0:4,0 0,30,247:10:0:6,0:4,0:10,0 +17 407 . A <*> 0 . DP=27;ADF=16,0;ADR=11,0;AD=27,0;I16=16,11,0,0,1007,38355,0,0,1558,91682,0,0,526,11538,0,0;QS=3,0;MQSB=0.992419;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,39,255:13:0:8,0:5,0:13,0 0,12,125:4:0:2,0:2,0:4,0 0,30,255:10:0:6,0:4,0:10,0 +17 408 . C <*> 0 . DP=28;ADF=16,0;ADR=11,0;AD=27,0;I16=16,11,0,0,1006,38136,0,0,1558,91682,0,0,521,11489,0,0;QS=3,0;MQSB=0.992419;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,42,255:14:0:8,0:6,0:14,0 0,9,110:3:0:2,0:1,0:3,0 0,30,244:10:0:6,0:4,0:10,0 +17 409 . T <*> 0 . DP=29;ADF=17,0;ADR=12,0;AD=29,0;I16=17,12,0,0,1100,42734,0,0,1678,98882,0,0,525,11503,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,42,255:14:0:8,0:6,0:14,0 0,12,131:4:0:2,0:2,0:4,0 0,33,255:11:0:7,0:4,0:11,0 +17 410 . T <*> 0 . DP=29;ADF=17,0;ADR=12,0;AD=29,0;I16=17,12,0,0,1035,38325,0,0,1678,98882,0,0,524,11432,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,42,255:14:0:8,0:6,0:14,0 0,12,125:4:0:2,0:2,0:4,0 0,33,255:11:0:7,0:4,0:11,0 +17 411 . T <*> 0 . DP=29;ADF=17,0;ADR=10,0;AD=27,0;I16=17,10,0,0,1003,37747,0,0,1558,91682,0,0,496,10716,0,0;QS=3,0;MQSB=0.984677;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,42,255:14:0:8,0:6,0:14,0 0,9,104:3:0:2,0:1,0:3,0 0,30,255:10:0:7,0:3,0:10,0 +17 412 . C T,<*> 0 . DP=30;ADF=17,1,0;ADR=12,0,0;AD=29,1,0;I16=17,12,1,0,1094,42458,14,196,1678,98882,60,3600,495,10659,25,625;QS=2.97455,0.0254545,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.991968;BQB=1;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,30,255,42,255,255:15:0:8,1,0:6,0,0:14,1,0 0,12,124,12,124,124:4:0:2,0,0:2,0,0:4,0,0 0,33,255,33,255,255:11:0:7,0,0:4,0,0:11,0,0 +17 413 . A <*> 0 . DP=31;ADF=18,0;ADR=13,0;AD=31,0;I16=18,13,0,0,1189,45985,0,0,1798,106082,0,0,520,11258,0,0;QS=3,0;MQSB=0.995005;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:9,0:8,0:17,0 0,9,102:3:0:2,0:1,0:3,0 0,33,255:11:0:7,0:4,0:11,0 +17 414 . T <*> 0 . DP=30;ADF=18,0;ADR=12,0;AD=30,0;I16=18,12,0,0,1151,44355,0,0,1738,102482,0,0,523,11265,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255:16:0:9,0:7,0:16,0 0,9,109:3:0:2,0:1,0:3,0 0,33,255:11:0:7,0:4,0:11,0 +17 415 . G <*> 0 . DP=30;ADF=18,0;ADR=12,0;AD=30,0;I16=18,12,0,0,1131,43175,0,0,1738,102482,0,0,526,11306,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255:16:0:9,0:7,0:16,0 0,9,110:3:0:2,0:1,0:3,0 0,33,255:11:0:7,0:4,0:11,0 +17 416 . G <*> 0 . DP=30;ADF=17,0;ADR=12,0;AD=29,0;I16=17,12,0,0,1083,41273,0,0,1678,98882,0,0,514,11156,0,0;QS=3,0;MQSB=0.993891;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255:16:0:9,0:7,0:16,0 0,9,114:3:0:2,0:1,0:3,0 0,30,253:10:0:6,0:4,0:10,0 +17 417 . C <*> 0 . DP=30;ADF=18,0;ADR=12,0;AD=30,0;I16=18,12,0,0,1114,42244,0,0,1738,102482,0,0,531,11439,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255:16:0:9,0:7,0:16,0 0,9,108:3:0:2,0:1,0:3,0 0,33,255:11:0:7,0:4,0:11,0 +17 418 . A <*> 0 . DP=30;ADF=18,0;ADR=12,0;AD=30,0;I16=18,12,0,0,1146,44248,0,0,1738,102482,0,0,532,11478,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255:16:0:9,0:7,0:16,0 0,9,111:3:0:2,0:1,0:3,0 0,33,255:11:0:7,0:4,0:11,0 +17 419 . T <*> 0 . DP=30;ADF=18,0;ADR=12,0;AD=30,0;I16=18,12,0,0,1117,42327,0,0,1738,102482,0,0,532,11498,0,0;QS=3,0;MQSB=0.991968;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255:16:0:9,0:7,0:16,0 0,9,112:3:0:2,0:1,0:3,0 0,33,255:11:0:7,0:4,0:11,0 +17 420 . A <*> 0 . DP=31;ADF=18,0;ADR=13,0;AD=31,0;I16=18,13,0,0,1117,41011,0,0,1798,106082,0,0,532,11550,0,0;QS=3,0;MQSB=0.995005;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255:16:0:9,0:7,0:16,0 0,9,108:3:0:2,0:1,0:3,0 0,36,255:12:0:7,0:5,0:12,0 +17 421 . A <*> 0 . DP=33;ADF=19,0;ADR=14,0;AD=33,0;I16=19,14,0,0,1208,45398,0,0,1887,110523,0,0,533,11635,0,0;QS=3,0;MQSB=0.986656;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255:16:0:9,0:7,0:16,0 0,9,113:3:0:2,0:1,0:3,0 0,42,255:14:0:8,0:6,0:14,0 +17 422 . A <*> 0 . DP=33;ADF=19,0;ADR=13,0;AD=32,0;I16=19,13,0,0,1205,46441,0,0,1827,106923,0,0,510,11082,0,0;QS=3,0;MQSB=0.991023;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255:16:0:9,0:7,0:16,0 0,9,116:3:0:2,0:1,0:3,0 0,39,255:13:0:8,0:5,0:13,0 +17 423 . T <*> 0 . DP=32;ADF=19,0;ADR=13,0;AD=32,0;I16=19,13,0,0,1202,45416,0,0,1827,106923,0,0,538,11818,0,0;QS=3,0;MQSB=0.991023;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255:16:0:9,0:7,0:16,0 0,9,110:3:0:2,0:1,0:3,0 0,39,255:13:0:8,0:5,0:13,0 +17 424 . A <*> 0 . DP=32;ADF=19,0;ADR=13,0;AD=32,0;I16=19,13,0,0,1147,41685,0,0,1827,106923,0,0,539,11867,0,0;QS=3,0;MQSB=0.991023;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255:16:0:9,0:7,0:16,0 0,9,106:3:0:2,0:1,0:3,0 0,39,255:13:0:8,0:5,0:13,0 +17 425 . A <*> 0 . DP=29;ADF=16,0;ADR=13,0;AD=29,0;I16=16,13,0,0,1070,40616,0,0,1647,96123,0,0,542,11900,0,0;QS=3,0;MQSB=0.976248;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,45,255:15:0:8,0:7,0:15,0 0,9,111:3:0:2,0:1,0:3,0 0,33,249:11:0:6,0:5,0:11,0 +17 426 . T <*> 0 . DP=29;ADF=16,0;ADR=12,0;AD=28,0;I16=16,12,0,0,997,36561,0,0,1587,92523,0,0,519,11287,0,0;QS=3,0;MQSB=0.982906;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,45,255:15:0:8,0:7,0:15,0 0,9,105:3:0:2,0:1,0:3,0 0,30,225:10:0:6,0:4,0:10,0 +17 427 . A <*> 0 . DP=29;ADF=16,0;ADR=13,0;AD=29,0;I16=16,13,0,0,1024,37266,0,0,1647,96123,0,0,546,11952,0,0;QS=3,0;MQSB=0.976248;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,45,255:15:0:8,0:7,0:15,0 0,9,111:3:0:2,0:1,0:3,0 0,33,242:11:0:6,0:5,0:11,0 +17 428 . C <*> 0 . DP=29;ADF=16,0;ADR=13,0;AD=29,0;I16=16,13,0,0,1064,39706,0,0,1647,96123,0,0,548,12020,0,0;QS=3,0;MQSB=0.976248;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,45,255:15:0:8,0:7,0:15,0 0,9,111:3:0:2,0:1,0:3,0 0,33,254:11:0:6,0:5,0:11,0 +17 429 . T <*> 0 . DP=30;ADF=16,0;ADR=14,0;AD=30,0;I16=16,14,0,0,1150,44918,0,0,1707,99723,0,0,549,12067,0,0;QS=3,0;MQSB=0.969373;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255:16:0:8,0:8,0:16,0 0,9,115:3:0:2,0:1,0:3,0 0,33,255:11:0:6,0:5,0:11,0 +17 430 . G <*> 0 . DP=30;ADF=16,0;ADR=14,0;AD=30,0;I16=16,14,0,0,1113,42443,0,0,1707,99723,0,0,551,12145,0,0;QS=3,0;MQSB=0.969373;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255:16:0:8,0:8,0:16,0 0,9,112:3:0:2,0:1,0:3,0 0,33,246:11:0:6,0:5,0:11,0 +17 431 . G <*> 0 . DP=30;ADF=14,0;ADR=14,0;AD=28,0;I16=14,14,0,0,1003,36953,0,0,1587,92523,0,0,553,12255,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,45,255:15:0:7,0:8,0:15,0 0,9,101:3:0:2,0:1,0:3,0 0,30,225:10:0:5,0:5,0:10,0 +17 432 . T <*> 0 . DP=28;ADF=14,0;ADR=14,0;AD=28,0;I16=14,14,0,0,1049,39621,0,0,1587,92523,0,0,556,12346,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,45,255:15:0:7,0:8,0:15,0 0,9,114:3:0:2,0:1,0:3,0 0,30,255:10:0:5,0:5,0:10,0 +17 433 . T <*> 0 . DP=28;ADF=14,0;ADR=12,0;AD=26,0;I16=14,12,0,0,949,35443,0,0,1467,85323,0,0,509,11217,0,0;QS=3,0;MQSB=0.967472;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,42,255:14:0:7,0:7,0:14,0 0,9,112:3:0:2,0:1,0:3,0 0,27,227:9:0:5,0:4,0:9,0 +17 434 . T <*> 0 . DP=29;ADF=15,0;ADR=14,0;AD=29,0;I16=15,14,0,0,1036,37654,0,0,1647,96123,0,0,561,12567,0,0;QS=3,0;MQSB=0.960561;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255:16:0:8,0:8,0:16,0 0,9,98:3:0:2,0:1,0:3,0 0,30,243:10:0:5,0:5,0:10,0 +17 435 . A <*> 0 . DP=29;ADF=15,0;ADR=13,0;AD=28,0;I16=15,13,0,0,1024,37970,0,0,1587,92523,0,0,556,12560,0,0;QS=3,0;MQSB=0.968414;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,45,255:15:0:8,0:7,0:15,0 0,9,103:3:0:2,0:1,0:3,0 0,30,237:10:0:5,0:5,0:10,0 +17 436 . T <*> 0 . DP=28;ADF=14,0;ADR=14,0;AD=28,0;I16=14,14,0,0,998,36220,0,0,1587,92523,0,0,564,12654,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255:16:0:8,0:8,0:16,0 0,9,110:3:0:2,0:1,0:3,0 0,27,223:9:0:4,0:5,0:9,0 +17 437 . T <*> 0 . DP=28;ADF=13,0;ADR=14,0;AD=27,0;I16=13,14,0,0,990,36832,0,0,1558,91682,0,0,549,12435,0,0;QS=3,0;MQSB=0.999706;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255:16:0:8,0:8,0:16,0 0,9,109:3:0:2,0:1,0:3,0 0,24,207:8:0:3,0:5,0:8,0 +17 438 . A <*> 0 . DP=28;ADF=14,0;ADR=13,0;AD=27,0;I16=14,13,0,0,972,35640,0,0,1527,88923,0,0,540,12082,0,0;QS=3,0;MQSB=0.9585;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255:16:0:8,0:8,0:16,0 0,9,107:3:0:2,0:1,0:3,0 0,24,216:8:0:4,0:4,0:8,0 +17 439 . C <*> 0 . DP=28;ADF=14,0;ADR=14,0;AD=28,0;I16=14,14,0,0,1055,40273,0,0,1587,92523,0,0,563,12649,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255:16:0:8,0:8,0:16,0 0,9,107:3:0:2,0:1,0:3,0 0,27,224:9:0:4,0:5,0:9,0 +17 440 . A <*> 0 . DP=28;ADF=14,0;ADR=14,0;AD=28,0;I16=14,14,0,0,1095,43251,0,0,1587,92523,0,0,561,12615,0,0;QS=3,0;MQSB=0.949591;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255:16:0:8,0:8,0:16,0 0,9,115:3:0:2,0:1,0:3,0 0,27,247:9:0:4,0:5,0:9,0 +17 441 . G <*> 0 . DP=29;ADF=15,0;ADR=14,0;AD=29,0;I16=15,14,0,0,1068,40344,0,0,1647,96123,0,0,559,12605,0,0;QS=3,0;MQSB=0.960561;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:9,0:8,0:17,0 0,9,104:3:0:2,0:1,0:3,0 0,27,198:9:0:4,0:5,0:9,0 +17 442 . A <*> 0 . DP=29;ADF=15,0;ADR=14,0;AD=29,0;I16=15,14,0,0,1091,41507,0,0,1647,96123,0,0,558,12620,0,0;QS=3,0;MQSB=0.960561;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:9,0:8,0:17,0 0,9,112:3:0:2,0:1,0:3,0 0,27,233:9:0:4,0:5,0:9,0 +17 443 . A <*> 0 . DP=30;ADF=15,0;ADR=14,0;AD=29,0;I16=15,14,0,0,1173,49439,0,0,1647,96123,0,0,557,12661,0,0;QS=3,0;MQSB=0.960561;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:9,0:8,0:17,0 0,9,129:3:0:2,0:1,0:3,0 0,27,246:9:0:4,0:5,0:9,0 +17 444 . G <*> 0 . DP=29;ADF=15,0;ADR=13,0;AD=28,0;I16=15,13,0,0,1095,44661,0,0,1587,92523,0,0,557,12727,0,0;QS=3,0;MQSB=0.968414;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:9,0:8,0:17,0 0,6,91:2:0:2,0:0,0:2,0 0,27,227:9:0:4,0:5,0:9,0 +17 445 . C <*> 0 . DP=30;ADF=16,0;ADR=13,0;AD=29,0;I16=16,13,0,0,1100,43706,0,0,1647,96123,0,0,557,12817,0,0;QS=3,0;MQSB=0.976248;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:9,0:8,0:17,0 0,9,111:3:0:3,0:0,0:3,0 0,27,219:9:0:4,0:5,0:9,0 +17 446 . A <*> 0 . DP=30;ADF=16,0;ADR=13,0;AD=29,0;I16=16,13,0,0,1107,44265,0,0,1647,96123,0,0,557,12881,0,0;QS=3,0;MQSB=0.976248;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:9,0:8,0:17,0 0,9,115:3:0:3,0:0,0:3,0 0,27,232:9:0:4,0:5,0:9,0 +17 447 . C <*> 0 . DP=29;ADF=16,0;ADR=12,0;AD=28,0;I16=16,12,0,0,1108,45364,0,0,1618,95282,0,0,555,12817,0,0;QS=3,0;MQSB=0.856268;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255:16:0:9,0:7,0:16,0 0,9,114:3:0:3,0:0,0:3,0 0,27,235:9:0:4,0:5,0:9,0 +17 448 . T <*> 0 . DP=29;ADF=16,0;ADR=12,0;AD=28,0;I16=16,12,0,0,1125,47237,0,0,1618,95282,0,0,553,12773,0,0;QS=3,0;MQSB=0.856268;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255:16:0:9,0:7,0:16,0 0,9,118:3:0:3,0:0,0:3,0 0,27,240:9:0:4,0:5,0:9,0 +17 449 . A <*> 0 . DP=28;ADF=15,0;ADR=12,0;AD=27,0;I16=15,12,0,0,1091,45981,0,0,1558,91682,0,0,552,12748,0,0;QS=3,0;MQSB=0.84246;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255:16:0:9,0:7,0:16,0 0,6,90:2:0:2,0:0,0:2,0 0,27,245:9:0:4,0:5,0:9,0 +17 450 . G <*> 0 . DP=28;ADF=15,0;ADR=12,0;AD=27,0;I16=15,12,0,0,1069,44603,0,0,1558,91682,0,0,551,12741,0,0;QS=3,0;MQSB=0.84246;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255:16:0:9,0:7,0:16,0 0,6,91:2:0:2,0:0,0:2,0 0,27,233:9:0:4,0:5,0:9,0 +17 451 . A <*> 0 . DP=28;ADF=15,0;ADR=12,0;AD=27,0;I16=15,12,0,0,1021,41371,0,0,1558,91682,0,0,550,12752,0,0;QS=3,0;MQSB=0.84246;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255:16:0:9,0:7,0:16,0 0,6,93:2:0:2,0:0,0:2,0 0,27,244:9:0:4,0:5,0:9,0 +17 452 . A <*> 0 . DP=31;ADF=18,0;ADR=11,0;AD=29,0;I16=18,11,0,0,1079,43353,0,0,1678,98882,0,0,530,12420,0,0;QS=3,0;MQSB=0.884952;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:11,0:7,0:18,0 0,9,110:3:0:3,0:0,0:3,0 0,24,225:8:0:4,0:4,0:8,0 +17 453 . A <*> 0 . DP=31;ADF=17,0;ADR=11,0;AD=28,0;I16=17,11,0,0,1037,41069,0,0,1649,98041,0,0,508,11882,0,0;QS=3,0;MQSB=0.967085;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:11,0:7,0:18,0 0,9,111:3:0:3,0:0,0:3,0 0,21,221:7:0:3,0:4,0:7,0 +17 454 . A <*> 0 . DP=31;ADF=18,0;ADR=12,0;AD=30,0;I16=18,12,0,0,1158,47028,0,0,1738,102482,0,0,554,12904,0,0;QS=3,0;MQSB=0.878946;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:10,0:7,0:17,0 0,9,113:3:0:3,0:0,0:3,0 0,30,255:10:0:5,0:5,0:10,0 +17 455 . T <*> 0 . DP=32;ADF=17,0;ADR=13,0;AD=30,0;I16=17,13,0,0,1148,46574,0,0,1715,100251,0,0,550,12864,0,0;QS=3,0;MQSB=0.973855;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255:16:0:9,0:7,0:16,0 0,9,113:3:0:3,0:0,0:3,0 0,33,255:11:0:5,0:6,0:11,0 +17 456 . G <*> 0 . DP=32;ADF=17,0;ADR=13,0;AD=30,0;I16=17,13,0,0,1161,47287,0,0,1746,103010,0,0,534,12296,0,0;QS=3,0;MQSB=0.998031;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:10,0:7,0:17,0 0,9,116:3:0:3,0:0,0:3,0 0,30,245:10:0:4,0:6,0:10,0 +17 457 . C <*> 0 . DP=33;ADF=19,0;ADR=13,0;AD=32,0;I16=19,13,0,0,1218,48642,0,0,1835,107451,0,0,563,12967,0,0;QS=3,0;MQSB=0.985204;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:11,0:7,0:18,0 0,9,118:3:0:3,0:0,0:3,0 0,33,255:11:0:5,0:6,0:11,0 +17 458 . A <*> 0 . DP=33;ADF=19,0;ADR=13,0;AD=32,0;I16=19,13,0,0,1226,49034,0,0,1835,107451,0,0,568,12990,0,0;QS=3,0;MQSB=0.985204;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:11,0:7,0:18,0 0,9,111:3:0:3,0:0,0:3,0 0,33,255:11:0:5,0:6,0:11,0 +17 459 . T <*> 0 . DP=33;ADF=18,0;ADR=13,0;AD=31,0;I16=18,13,0,0,1167,46981,0,0,1775,103851,0,0,565,12945,0,0;QS=3,0;MQSB=0.980167;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:11,0:7,0:18,0 0,6,92:2:0:2,0:0,0:2,0 0,33,255:11:0:5,0:6,0:11,0 +17 460 . G <*> 0 . DP=32;ADF=19,0;ADR=12,0;AD=31,0;I16=19,12,0,0,1219,50105,0,0,1775,103851,0,0,575,12929,0,0;QS=3,0;MQSB=0.989977;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:11,0:7,0:18,0 0,9,116:3:0:3,0:0,0:3,0 0,30,255:10:0:5,0:5,0:10,0 +17 461 . T <*> 0 . DP=32;ADF=19,0;ADR=12,0;AD=31,0;I16=19,12,0,0,1213,49819,0,0,1775,103851,0,0,577,12845,0,0;QS=3,0;MQSB=0.989977;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:11,0:7,0:18,0 0,9,115:3:0:3,0:0,0:3,0 0,30,255:10:0:5,0:5,0:10,0 +17 462 . G <*> 0 . DP=32;ADF=19,0;ADR=12,0;AD=31,0;I16=19,12,0,0,1190,48962,0,0,1775,103851,0,0,580,12792,0,0;QS=3,0;MQSB=0.989977;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:10,0:7,0:17,0 0,12,119:4:0:4,0:0,0:4,0 0,30,241:10:0:5,0:5,0:10,0 +17 463 . G <*> 0 . DP=32;ADF=19,0;ADR=12,0;AD=31,0;I16=19,12,0,0,1114,44214,0,0,1775,103851,0,0,584,12770,0,0;QS=3,0;MQSB=0.989977;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:10,0:7,0:17,0 0,12,114:4:0:4,0:0,0:4,0 0,30,221:10:0:5,0:5,0:10,0 +17 464 . A <*> 0 . DP=32;ADF=18,0;ADR=11,0;AD=29,0;I16=18,11,0,0,1100,43908,0,0,1686,99410,0,0,556,12106,0,0;QS=3,0;MQSB=0.99095;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:10,0:7,0:17,0 0,12,133:4:0:4,0:0,0:4,0 0,24,213:8:0:4,0:4,0:8,0 +17 465 . C <*> 0 . DP=33;ADF=20,0;ADR=11,0;AD=31,0;I16=20,11,0,0,1191,48085,0,0,1775,103851,0,0,586,12786,0,0;QS=3,0;MQSB=0.996597;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:10,0:7,0:17,0 0,15,140:5:0:5,0:0,0:5,0 0,27,231:9:0:5,0:4,0:9,0 +17 466 . A <*> 0 . DP=34;ADF=21,0;ADR=12,0;AD=33,0;I16=21,12,0,0,1293,53311,0,0,1895,111051,0,0,597,12897,0,0;QS=3,0;MQSB=0.995633;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:11,0:7,0:18,0 0,15,154:5:0:5,0:0,0:5,0 0,30,255:10:0:5,0:5,0:10,0 +17 467 . A <*> 0 . DP=34;ADF=21,0;ADR=11,0;AD=32,0;I16=21,11,0,0,1256,51450,0,0,1835,107451,0,0,597,12891,0,0;QS=3,0;MQSB=0.998231;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:11,0:7,0:18,0 0,15,157:5:0:5,0:0,0:5,0 0,27,248:9:0:5,0:4,0:9,0 +17 468 . A <*> 0 . DP=35;ADF=22,0;ADR=12,0;AD=34,0;I16=22,12,0,0,1274,51268,0,0,1955,114651,0,0,604,12904,0,0;QS=3,0;MQSB=0.997406;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,57,255:19:0:12,0:7,0:19,0 0,15,154:5:0:5,0:0,0:5,0 0,30,251:10:0:5,0:5,0:10,0 +17 469 . A <*> 0 . DP=35;ADF=22,0;ADR=12,0;AD=34,0;I16=22,12,0,0,1285,52989,0,0,1955,114651,0,0,608,12940,0,0;QS=3,0;MQSB=0.997406;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,57,255:19:0:12,0:7,0:19,0 0,15,146:5:0:5,0:0,0:5,0 0,30,255:10:0:5,0:5,0:10,0 +17 470 . G <*> 0 . DP=35;ADF=22,0;ADR=12,0;AD=34,0;I16=22,12,0,0,1281,51055,0,0,1955,114651,0,0,612,13016,0,0;QS=3,0;MQSB=0.997406;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,57,255:19:0:12,0:7,0:19,0 0,15,148:5:0:5,0:0,0:5,0 0,30,238:10:0:5,0:5,0:10,0 +17 471 . T <*> 0 . DP=36;ADF=22,0;ADR=11,0;AD=33,0;I16=22,11,0,0,1239,49021,0,0,1918,113282,0,0,599,12825,0,0;QS=3,0;MQSB=0.915545;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,57,255:19:0:12,0:7,0:19,0 0,15,150:5:0:5,0:0,0:5,0 0,27,232:9:0:5,0:4,0:9,0 +17 472 . T <*> 0 . DP=35;ADF=21,0;ADR=12,0;AD=33,0;I16=21,12,0,0,1245,48915,0,0,1926,113810,0,0,595,12559,0,0;QS=3,0;MQSB=0.988858;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,57,255:19:0:12,0:7,0:19,0 0,15,153:5:0:5,0:0,0:5,0 0,27,237:9:0:4,0:5,0:9,0 +17 473 . G <*> 0 . DP=35;ADF=21,0;ADR=12,0;AD=33,0;I16=21,12,0,0,1307,53473,0,0,1926,113810,0,0,599,12651,0,0;QS=3,0;MQSB=0.988858;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,57,255:19:0:12,0:7,0:19,0 0,15,141:5:0:5,0:0,0:5,0 0,27,249:9:0:4,0:5,0:9,0 +17 474 . G <*> 0 . DP=36;ADF=22,0;ADR=12,0;AD=34,0;I16=22,12,0,0,1284,51708,0,0,1986,117410,0,0,602,12734,0,0;QS=3,0;MQSB=0.986937;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,57,255:19:0:12,0:7,0:19,0 0,15,131:5:0:5,0:0,0:5,0 0,30,255:10:0:5,0:5,0:10,0 +17 475 . G <*> 0 . DP=36;ADF=23,0;ADR=12,0;AD=35,0;I16=23,12,0,0,1311,51609,0,0,2015,118251,0,0,631,13485,0,0;QS=3,0;MQSB=0.998642;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,57,255:19:0:12,0:7,0:19,0 0,15,141:5:0:5,0:0,0:5,0 0,33,252:11:0:6,0:5,0:11,0 +17 476 . A <*> 0 . DP=36;ADF=23,0;ADR=12,0;AD=35,0;I16=23,12,0,0,1312,52078,0,0,2015,118251,0,0,634,13606,0,0;QS=3,0;MQSB=0.998642;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,57,255:19:0:12,0:7,0:19,0 0,15,157:5:0:5,0:0,0:5,0 0,33,255:11:0:6,0:5,0:11,0 +17 477 . T <*> 0 . DP=36;ADF=23,0;ADR=12,0;AD=35,0;I16=23,12,0,0,1318,52668,0,0,2015,118251,0,0,637,13773,0,0;QS=3,0;MQSB=0.998642;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,57,255:19:0:12,0:7,0:19,0 0,15,148:5:0:5,0:0,0:5,0 0,33,255:11:0:6,0:5,0:11,0 +17 478 . T <*> 0 . DP=38;ADF=25,0;ADR=12,0;AD=37,0;I16=25,12,0,0,1338,51774,0,0,2135,125451,0,0,637,13833,0,0;QS=3,0;MQSB=0.999868;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,60,255:20:0:13,0:7,0:20,0 0,18,154:6:0:6,0:0,0:6,0 0,33,255:11:0:6,0:5,0:11,0 +17 479 . A <*> 0 . DP=38;ADF=25,0;ADR=12,0;AD=37,0;I16=25,12,0,0,1420,57788,0,0,2135,125451,0,0,639,13935,0,0;QS=3,0;MQSB=0.999868;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,60,255:20:0:13,0:7,0:20,0 0,18,163:6:0:6,0:0,0:6,0 0,33,255:11:0:6,0:5,0:11,0 +17 480 . G <*> 0 . DP=37;ADF=25,0;ADR=11,0;AD=36,0;I16=25,11,0,0,1438,60172,0,0,2075,121851,0,0,641,14029,0,0;QS=3,0;MQSB=0.999853;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,57,255:19:0:13,0:6,0:19,0 0,18,165:6:0:6,0:0,0:6,0 0,33,255:11:0:6,0:5,0:11,0 +17 481 . G <*> 0 . DP=37;ADF=25,0;ADR=11,0;AD=36,0;I16=25,11,0,0,1392,55824,0,0,2075,121851,0,0,642,14112,0,0;QS=3,0;MQSB=0.999853;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,57,255:19:0:13,0:6,0:19,0 0,18,165:6:0:6,0:0,0:6,0 0,33,255:11:0:6,0:5,0:11,0 +17 482 . A <*> 0 . DP=37;ADF=24,0;ADR=11,0;AD=35,0;I16=24,11,0,0,1352,55134,0,0,2015,118251,0,0,618,13608,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,57,255:19:0:13,0:6,0:19,0 0,15,143:5:0:5,0:0,0:5,0 0,33,255:11:0:6,0:5,0:11,0 +17 483 . G <*> 0 . DP=37;ADF=24,0;ADR=12,0;AD=36,0;I16=24,12,0,0,1417,57747,0,0,2075,121851,0,0,642,14240,0,0;QS=3,0;MQSB=0.999437;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,57,255:19:0:12,0:7,0:19,0 0,18,165:6:0:6,0:0,0:6,0 0,33,255:11:0:6,0:5,0:11,0 +17 484 . A <*> 0 . DP=36;ADF=24,0;ADR=11,0;AD=35,0;I16=24,11,0,0,1340,53992,0,0,2015,118251,0,0,643,14281,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:12,0:6,0:18,0 0,18,168:6:0:6,0:0,0:6,0 0,33,255:11:0:6,0:5,0:11,0 +17 485 . G <*> 0 . DP=35;ADF=23,0;ADR=12,0;AD=35,0;I16=23,12,0,0,1329,51411,0,0,2015,118251,0,0,669,14931,0,0;QS=3,0;MQSB=0.998642;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:12,0:6,0:18,0 0,18,160:6:0:5,0:1,0:6,0 0,33,255:11:0:6,0:5,0:11,0 +17 486 . A <*> 0 . DP=34;ADF=22,0;ADR=12,0;AD=34,0;I16=22,12,0,0,1311,51523,0,0,1955,114651,0,0,671,14989,0,0;QS=3,0;MQSB=0.997406;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:11,0:6,0:17,0 0,18,173:6:0:5,0:1,0:6,0 0,33,255:11:0:6,0:5,0:11,0 +17 487 . G <*> 0 . DP=34;ADF=22,0;ADR=12,0;AD=34,0;I16=22,12,0,0,1306,50760,0,0,1955,114651,0,0,672,15030,0,0;QS=3,0;MQSB=0.997406;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:11,0:6,0:17,0 0,18,169:6:0:5,0:1,0:6,0 0,33,255:11:0:6,0:5,0:11,0 +17 488 . A <*> 0 . DP=35;ADF=22,0;ADR=12,0;AD=34,0;I16=22,12,0,0,1274,48140,0,0,1986,117410,0,0,646,14380,0,0;QS=3,0;MQSB=0.986937;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:12,0:6,0:18,0 0,18,177:6:0:5,0:1,0:6,0 0,30,255:10:0:5,0:5,0:10,0 +17 489 . A <*> 0 . DP=35;ADF=23,0;ADR=12,0;AD=35,0;I16=23,12,0,0,1264,46916,0,0,2015,118251,0,0,671,15015,0,0;QS=3,0;MQSB=0.998642;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:12,0:6,0:18,0 0,18,175:6:0:5,0:1,0:6,0 0,33,255:11:0:6,0:5,0:11,0 +17 490 . A <*> 0 . DP=36;ADF=24,0;ADR=12,0;AD=36,0;I16=24,12,0,0,1332,50280,0,0,2075,121851,0,0,671,15061,0,0;QS=3,0;MQSB=0.999437;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:12,0:6,0:18,0 0,21,188:7:0:6,0:1,0:7,0 0,33,255:11:0:6,0:5,0:11,0 +17 491 . T <*> 0 . DP=36;ADF=24,0;ADR=12,0;AD=36,0;I16=24,12,0,0,1284,46802,0,0,2075,121851,0,0,671,15093,0,0;QS=3,0;MQSB=0.999437;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:12,0:6,0:18,0 0,21,178:7:0:6,0:1,0:7,0 0,33,255:11:0:6,0:5,0:11,0 +17 492 . G <*> 0 . DP=35;ADF=21,0;ADR=12,0;AD=33,0;I16=21,12,0,0,1252,48326,0,0,1926,113810,0,0,621,13859,0,0;QS=3,0;MQSB=0.988858;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:11,0:6,0:17,0 0,18,172:6:0:5,0:1,0:6,0 0,30,251:10:0:5,0:5,0:10,0 +17 493 . A <*> 0 . DP=34;ADF=22,0;ADR=11,0;AD=33,0;I16=22,11,0,0,1273,49481,0,0,1926,113810,0,0,650,14672,0,0;QS=3,0;MQSB=0.981935;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:12,0:6,0:18,0 0,21,186:7:0:6,0:1,0:7,0 0,24,240:8:0:4,0:4,0:8,0 +17 494 . A <*> 0 . DP=34;ADF=22,0;ADR=12,0;AD=34,0;I16=22,12,0,0,1326,52604,0,0,1986,117410,0,0,672,15182,0,0;QS=3,0;MQSB=0.986937;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:12,0:6,0:18,0 0,21,196:7:0:6,0:1,0:7,0 0,27,255:9:0:4,0:5,0:9,0 +17 495 . G <*> 0 . DP=34;ADF=21,0;ADR=12,0;AD=33,0;I16=21,12,0,0,1255,48577,0,0,1926,113810,0,0,647,14611,0,0;QS=3,0;MQSB=0.988858;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:12,0:6,0:18,0 0,18,168:6:0:5,0:1,0:6,0 0,27,244:9:0:4,0:5,0:9,0 +17 496 . A <*> 0 . DP=34;ADF=22,0;ADR=12,0;AD=34,0;I16=22,12,0,0,1250,46926,0,0,1986,117410,0,0,670,15220,0,0;QS=3,0;MQSB=0.986937;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:12,0:6,0:18,0 0,21,186:7:0:6,0:1,0:7,0 0,27,249:9:0:4,0:5,0:9,0 +17 497 . C <*> 0 . DP=34;ADF=22,0;ADR=12,0;AD=34,0;I16=22,12,0,0,1250,47006,0,0,1986,117410,0,0,665,15087,0,0;QS=3,0;MQSB=0.986937;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:12,0:6,0:18,0 0,21,164:7:0:6,0:1,0:7,0 0,27,239:9:0:4,0:5,0:9,0 +17 498 . A <*> 0 . DP=34;ADF=22,0;ADR=12,0;AD=34,0;I16=22,12,0,0,1286,49158,0,0,1986,117410,0,0,661,14987,0,0;QS=3,0;MQSB=0.986937;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:12,0:6,0:18,0 0,21,185:7:0:6,0:1,0:7,0 0,27,252:9:0:4,0:5,0:9,0 +17 499 . T <*> 0 . DP=34;ADF=23,0;ADR=11,0;AD=34,0;I16=23,11,0,0,1224,45284,0,0,1986,117410,0,0,659,14919,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:12,0:5,0:17,0 0,21,183:7:0:6,0:1,0:7,0 0,30,255:10:0:5,0:5,0:10,0 +17 500 . A <*> 0 . DP=34;ADF=23,0;ADR=11,0;AD=34,0;I16=23,11,0,0,1230,45152,0,0,1986,117410,0,0,657,14833,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:12,0:5,0:17,0 0,21,179:7:0:6,0:1,0:7,0 0,30,255:10:0:5,0:5,0:10,0 +17 501 . T <*> 0 . DP=33;ADF=23,0;ADR=10,0;AD=33,0;I16=23,10,0,0,1241,47167,0,0,1926,113810,0,0,656,14778,0,0;QS=3,0;MQSB=0.972757;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:12,0:5,0:17,0 0,21,186:7:0:6,0:1,0:7,0 0,27,241:9:0:5,0:4,0:9,0 +17 502 . G <*> 0 . DP=33;ADF=23,0;ADR=10,0;AD=33,0;I16=23,10,0,0,1215,45829,0,0,1926,113810,0,0,655,14753,0,0;QS=3,0;MQSB=0.972757;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:12,0:5,0:17,0 0,21,183:7:0:6,0:1,0:7,0 0,27,235:9:0:5,0:4,0:9,0 +17 503 . T <*> 0 . DP=34;ADF=23,0;ADR=11,0;AD=34,0;I16=23,11,0,0,1194,43366,0,0,1986,117410,0,0,654,14758,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:12,0:6,0:18,0 0,21,177:7:0:6,0:1,0:7,0 0,27,234:9:0:5,0:4,0:9,0 +17 504 . C <*> 0 . DP=34;ADF=23,0;ADR=11,0;AD=34,0;I16=23,11,0,0,1218,45552,0,0,1986,117410,0,0,651,14643,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:12,0:6,0:18,0 0,21,183:7:0:6,0:1,0:7,0 0,27,219:9:0:5,0:4,0:9,0 +17 505 . C <*> 0 . DP=35;ADF=23,0;ADR=11,0;AD=34,0;I16=23,11,0,0,1207,44321,0,0,1986,117410,0,0,641,14509,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:12,0:6,0:18,0 0,21,189:7:0:6,0:1,0:7,0 0,27,221:9:0:5,0:4,0:9,0 +17 506 . A <*> 0 . DP=35;ADF=24,0;ADR=11,0;AD=35,0;I16=24,11,0,0,1266,46776,0,0,2046,121010,0,0,646,14504,0,0;QS=3,0;MQSB=0.977529;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,57,255:19:0:13,0:6,0:19,0 0,21,188:7:0:6,0:1,0:7,0 0,27,231:9:0:5,0:4,0:9,0 +17 507 . C <*> 0 . DP=35;ADF=23,0;ADR=11,0;AD=34,0;I16=23,11,0,0,1220,45016,0,0,1986,117410,0,0,635,14401,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:12,0:6,0:18,0 0,21,183:7:0:6,0:1,0:7,0 0,27,226:9:0:5,0:4,0:9,0 +17 508 . A <*> 0 . DP=34;ADF=24,0;ADR=10,0;AD=34,0;I16=24,10,0,0,1204,44542,0,0,1986,117410,0,0,643,14491,0,0;QS=3,0;MQSB=0.970272;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:13,0:5,0:18,0 0,21,189:7:0:6,0:1,0:7,0 0,27,220:9:0:5,0:4,0:9,0 +17 509 . C <*> 0 . DP=34;ADF=24,0;ADR=10,0;AD=34,0;I16=24,10,0,0,1272,48272,0,0,1986,117410,0,0,640,14430,0,0;QS=3,0;MQSB=0.970272;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:13,0:5,0:18,0 0,21,186:7:0:6,0:1,0:7,0 0,27,241:9:0:5,0:4,0:9,0 +17 510 . A <*> 0 . DP=34;ADF=22,0;ADR=11,0;AD=33,0;I16=22,11,0,0,1194,44196,0,0,1926,113810,0,0,613,13773,0,0;QS=3,0;MQSB=0.981935;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:12,0:6,0:18,0 0,21,187:7:0:6,0:1,0:7,0 0,24,221:8:0:4,0:4,0:8,0 +17 511 . A <*> 0 . DP=34;ADF=23,0;ADR=11,0;AD=34,0;I16=23,11,0,0,1222,45562,0,0,1986,117410,0,0,637,14395,0,0;QS=3,0;MQSB=0.979712;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,57,255:19:0:13,0:6,0:19,0 0,21,195:7:0:6,0:1,0:7,0 0,24,233:8:0:4,0:4,0:8,0 +17 512 . A C,<*> 0 . DP=33;ADF=22,0,0;ADR=10,1,0;AD=32,1,0;I16=22,10,0,1,1121,40793,13,169,1866,110210,60,3600,628,14340,9,81;QS=2.97719,0.022807,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.981935;BQB=1;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,39,255,51,255,255:18:0:12,0,0:5,1,0:17,1,0 0,21,183,21,183,183:7:0:6,0,0:1,0,0:7,0,0 0,24,231,24,231,231:8:0:4,0,0:4,0,0:8,0,0 +17 513 . A <*> 0 . DP=32;ADF=20,0;ADR=10,0;AD=30,0;I16=20,10,0,0,1115,42183,0,0,1746,103010,0,0,598,13624,0,0;QS=3,0;MQSB=0.980594;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255:16:0:11,0:5,0:16,0 0,18,175:6:0:5,0:1,0:6,0 0,24,233:8:0:4,0:4,0:8,0 +17 514 . A T,<*> 0 . DP=32;ADF=20,0,0;ADR=9,1,0;AD=29,1,0;I16=20,9,0,1,1066,40004,16,256,1686,99410,60,3600,586,13500,11,121;QS=2.97075,0.0292505,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.980594;BQB=1;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,31,255,45,255,255:16:0:11,0,0:4,1,0:15,1,0 0,18,171,18,171,171:6:0:5,0,0:1,0,0:6,0,0 0,24,235,24,235,235:8:0:4,0,0:4,0,0:8,0,0 +17 515 . C <*> 0 . DP=32;ADF=18,0;ADR=10,0;AD=28,0;I16=18,10,0,0,1010,37294,0,0,1626,95810,0,0,561,12915,0,0;QS=3,0;MQSB=0.986018;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,42,255:14:0:9,0:5,0:14,0 0,18,167:6:0:5,0:1,0:6,0 0,24,211:8:0:4,0:4,0:8,0 +17 516 . C <*> 0 . DP=32;ADF=21,0;ADR=10,0;AD=31,0;I16=21,10,0,0,1100,40570,0,0,1806,106610,0,0,612,13954,0,0;QS=3,0;MQSB=0.977926;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255:16:0:11,0:5,0:16,0 0,21,187:7:0:6,0:1,0:7,0 0,24,215:8:0:4,0:4,0:8,0 +17 517 . T <*> 0 . DP=33;ADF=23,0;ADR=10,0;AD=33,0;I16=23,10,0,0,1269,49995,0,0,1926,113810,0,0,636,14626,0,0;QS=3,0;MQSB=0.972757;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:13,0:5,0:18,0 0,21,201:7:0:6,0:1,0:7,0 0,24,242:8:0:4,0:4,0:8,0 +17 518 . G <*> 0 . DP=34;ADF=24,0;ADR=10,0;AD=34,0;I16=24,10,0,0,1247,46839,0,0,1986,117410,0,0,636,14696,0,0;QS=3,0;MQSB=0.970272;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,57,255:19:0:14,0:5,0:19,0 0,21,182:7:0:6,0:1,0:7,0 0,24,220:8:0:4,0:4,0:8,0 +17 519 . T <*> 0 . DP=36;ADF=25,0;ADR=11,0;AD=36,0;I16=25,11,0,0,1283,46693,0,0,2106,124610,0,0,636,14742,0,0;QS=3,0;MQSB=0.975394;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,63,255:21:0:15,0:6,0:21,0 0,21,177:7:0:6,0:1,0:7,0 0,24,224:8:0:4,0:4,0:8,0 +17 520 . T <*> 0 . DP=36;ADF=24,0;ADR=11,0;AD=35,0;I16=24,11,0,0,1238,44894,0,0,2046,121010,0,0,613,14193,0,0;QS=3,0;MQSB=0.977529;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,60,255:20:0:14,0:6,0:20,0 0,21,180:7:0:6,0:1,0:7,0 0,24,223:8:0:4,0:4,0:8,0 +17 521 . C <*> 0 . DP=34;ADF=25,0;ADR=9,0;AD=34,0;I16=25,9,0,0,1280,49454,0,0,1986,117410,0,0,641,14875,0,0;QS=3,0;MQSB=0.958048;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,60,255:20:0:15,0:5,0:20,0 0,21,191:7:0:6,0:1,0:7,0 0,21,204:7:0:4,0:3,0:7,0 +17 522 . A <*> 0 . DP=32;ADF=24,0;ADR=8,0;AD=32,0;I16=24,8,0,0,1158,43228,0,0,1897,112969,0,0,646,14960,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,60,255:20:0:15,0:5,0:20,0 0,21,185:7:0:6,0:1,0:7,0 0,15,170:5:0:3,0:2,0:5,0 +17 523 . T G,<*> 0 . DP=32;ADF=23,1,0;ADR=8,0,0;AD=31,1,0;I16=23,8,1,0,1184,45708,15,225,1837,109369,60,3600,626,14446,25,625;QS=2.9794,0.0206044,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.872525;BQB=1;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,44,255,57,255,255:20:0:14,1,0:5,0,0:19,1,0 0,21,191,21,191,191:7:0:6,0,0:1,0,0:7,0,0 0,15,166,15,166,166:5:0:3,0,0:2,0,0:5,0,0 +17 524 . T <*> 0 . DP=32;ADF=24,0;ADR=7,0;AD=31,0;I16=24,7,0,0,1084,39474,0,0,1837,109369,0,0,629,14483,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,60,255:20:0:15,0:5,0:20,0 0,21,194:7:0:6,0:1,0:7,0 0,12,140:4:0:3,0:1,0:4,0 +17 525 . G <*> 0 . DP=32;ADF=24,0;ADR=7,0;AD=31,0;I16=24,7,0,0,1181,45669,0,0,1837,109369,0,0,631,14495,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,60,255:20:0:15,0:5,0:20,0 0,21,188:7:0:6,0:1,0:7,0 0,12,129:4:0:3,0:1,0:4,0 +17 526 . C <*> 0 . DP=32;ADF=24,0;ADR=7,0;AD=31,0;I16=24,7,0,0,1146,43950,0,0,1860,111600,0,0,633,14531,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,60,255:20:0:15,0:5,0:20,0 0,21,185:7:0:6,0:1,0:7,0 0,12,131:4:0:3,0:1,0:4,0 +17 527 . A <*> 0 . DP=33;ADF=24,0;ADR=8,0;AD=32,0;I16=24,8,0,0,1209,46265,0,0,1897,112969,0,0,636,14634,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,57,255:19:0:14,0:5,0:19,0 0,21,194:7:0:6,0:1,0:7,0 0,18,181:6:0:4,0:2,0:6,0 +17 528 . G <*> 0 . DP=33;ADF=24,0;ADR=8,0;AD=32,0;I16=24,8,0,0,1256,49824,0,0,1897,112969,0,0,634,14484,0,0;QS=3,0;MQSB=0.872525;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,60,255:20:0:15,0:5,0:20,0 0,18,169:6:0:5,0:1,0:6,0 0,18,193:6:0:4,0:2,0:6,0 +17 529 . C <*> 0 . DP=32;ADF=24,0;ADR=7,0;AD=31,0;I16=24,7,0,0,1148,44362,0,0,1837,109369,0,0,633,14357,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:14,0:4,0:18,0 0,21,187:7:0:6,0:1,0:7,0 0,18,184:6:0:4,0:2,0:6,0 +17 530 . T <*> 0 . DP=32;ADF=25,0;ADR=7,0;AD=32,0;I16=25,7,0,0,1244,49168,0,0,1897,112969,0,0,657,14883,0,0;QS=3,0;MQSB=0.850154;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,57,255:19:0:15,0:4,0:19,0 0,21,196:7:0:6,0:1,0:7,0 0,18,202:6:0:4,0:2,0:6,0 +17 531 . T <*> 0 . DP=32;ADF=25,0;ADR=7,0;AD=32,0;I16=25,7,0,0,1177,44171,0,0,1897,112969,0,0,654,14714,0,0;QS=3,0;MQSB=0.850154;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,57,255:19:0:15,0:4,0:19,0 0,21,181:7:0:6,0:1,0:7,0 0,18,193:6:0:4,0:2,0:6,0 +17 532 . T <*> 0 . DP=32;ADF=24,0;ADR=7,0;AD=31,0;I16=24,7,0,0,1153,43543,0,0,1837,109369,0,0,630,14116,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:14,0:4,0:18,0 0,21,181:7:0:6,0:1,0:7,0 0,18,192:6:0:4,0:2,0:6,0 +17 533 . C <*> 0 . DP=32;ADF=24,0;ADR=7,0;AD=31,0;I16=24,7,0,0,1142,43940,0,0,1837,109369,0,0,619,13649,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:14,0:4,0:18,0 0,21,178:7:0:6,0:1,0:7,0 0,18,180:6:0:4,0:2,0:6,0 +17 534 . T <*> 0 . DP=31;ADF=24,0;ADR=6,0;AD=30,0;I16=24,6,0,0,1212,49426,0,0,1777,105769,0,0,615,13479,0,0;QS=3,0;MQSB=0.82403;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:14,0:3,0:17,0 0,21,205:7:0:6,0:1,0:7,0 0,18,205:6:0:4,0:2,0:6,0 +17 535 . A <*> 0 . DP=31;ADF=24,0;ADR=6,0;AD=30,0;I16=24,6,0,0,1080,39870,0,0,1777,105769,0,0,611,13341,0,0;QS=3,0;MQSB=0.82403;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:14,0:3,0:17,0 0,21,194:7:0:6,0:1,0:7,0 0,18,189:6:0:4,0:2,0:6,0 +17 536 . C <*> 0 . DP=31;ADF=24,0;ADR=7,0;AD=31,0;I16=24,7,0,0,1097,40707,0,0,1837,109369,0,0,631,13809,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:14,0:4,0:18,0 0,21,184:7:0:6,0:1,0:7,0 0,18,157:6:0:4,0:2,0:6,0 +17 537 . C <*> 0 . DP=31;ADF=22,0;ADR=7,0;AD=29,0;I16=22,7,0,0,1034,38564,0,0,1717,102169,0,0,587,12861,0,0;QS=3,0;MQSB=0.854582;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255:16:0:12,0:4,0:16,0 0,21,172:7:0:6,0:1,0:7,0 0,18,183:6:0:4,0:2,0:6,0 +17 538 . A <*> 0 . DP=31;ADF=24,0;ADR=7,0;AD=31,0;I16=24,7,0,0,1138,42478,0,0,1837,109369,0,0,620,13536,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:14,0:4,0:18,0 0,21,189:7:0:6,0:1,0:7,0 0,18,181:6:0:4,0:2,0:6,0 +17 539 . T <*> 0 . DP=31;ADF=24,0;ADR=7,0;AD=31,0;I16=24,7,0,0,1134,42070,0,0,1837,109369,0,0,614,13422,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:14,0:4,0:18,0 0,21,178:7:0:6,0:1,0:7,0 0,18,181:6:0:4,0:2,0:6,0 +17 540 . C <*> 0 . DP=31;ADF=24,0;ADR=7,0;AD=31,0;I16=24,7,0,0,1148,43768,0,0,1837,109369,0,0,608,13340,0,0;QS=3,0;MQSB=0.851535;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:14,0:4,0:18,0 0,21,177:7:0:6,0:1,0:7,0 0,18,178:6:0:4,0:2,0:6,0 +17 541 . A <*> 0 . DP=32;ADF=24,0;ADR=6,0;AD=30,0;I16=24,6,0,0,1083,40483,0,0,1777,105769,0,0,551,11991,0,0;QS=3,0;MQSB=0.82403;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:13,0:4,0:17,0 0,24,180:8:0:7,0:1,0:8,0 0,15,150:5:0:4,0:1,0:5,0 +17 542 . C <*> 0 . DP=33;ADF=25,0;ADR=6,0;AD=31,0;I16=25,6,0,0,1123,41759,0,0,1837,109369,0,0,570,12552,0,0;QS=3,0;MQSB=0.822578;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:14,0:3,0:17,0 0,24,172:8:0:7,0:1,0:8,0 0,18,174:6:0:4,0:2,0:6,0 +17 543 . C <*> 0 . DP=34;ADF=25,0;ADR=9,0;AD=34,0;I16=25,9,0,0,1219,45959,0,0,1986,117410,0,0,601,13245,0,0;QS=3,0;MQSB=0.621145;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,57,255:19:0:14,0:5,0:19,0 0,27,194:9:0:7,0:2,0:9,0 0,18,188:6:0:4,0:2,0:6,0 +17 544 . A <*> 0 . DP=33;ADF=24,0;ADR=8,0;AD=32,0;I16=24,8,0,0,1170,43898,0,0,1866,110210,0,0,570,12506,0,0;QS=3,0;MQSB=0.579578;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:13,0:5,0:18,0 0,24,192:8:0:7,0:1,0:8,0 0,18,180:6:0:4,0:2,0:6,0 +17 545 . A <*> 0 . DP=33;ADF=25,0;ADR=8,0;AD=33,0;I16=25,8,0,0,1174,43602,0,0,1926,113810,0,0,587,12951,0,0;QS=3,0;MQSB=0.576102;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,57,255:19:0:14,0:5,0:19,0 0,24,190:8:0:7,0:1,0:8,0 0,18,184:6:0:4,0:2,0:6,0 +17 546 . A <*> 0 . DP=32;ADF=24,0;ADR=8,0;AD=32,0;I16=24,8,0,0,1126,41444,0,0,1866,110210,0,0,580,12802,0,0;QS=3,0;MQSB=0.579578;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,57,255:19:0:14,0:5,0:19,0 0,21,166:7:0:6,0:1,0:7,0 0,18,193:6:0:4,0:2,0:6,0 +17 547 . A <*> 0 . DP=32;ADF=24,0;ADR=7,0;AD=31,0;I16=24,7,0,0,1129,42381,0,0,1806,106610,0,0,547,12009,0,0;QS=3,0;MQSB=0.525788;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:14,0:4,0:18,0 0,21,180:7:0:6,0:1,0:7,0 0,18,195:6:0:4,0:2,0:6,0 +17 548 . A <*> 0 . DP=33;ADF=23,0;ADR=9,0;AD=32,0;I16=23,9,0,0,1153,42673,0,0,1866,110210,0,0,561,12489,0,0;QS=3,0;MQSB=0.628357;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:13,0:5,0:18,0 0,21,181:7:0:6,0:1,0:7,0 0,21,211:7:0:4,0:3,0:7,0 +17 549 . T G,<*> 0 . DP=32;ADF=22,0,0;ADR=8,1,0;AD=30,1,0;I16=22,8,0,1,1101,40987,20,400,1746,103010,60,3600,530,11716,25,625;QS=2.96748,0.0325203,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.632337;BQB=1;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,31,255,48,255,255:17:0:12,0,0:4,1,0:16,1,0 0,21,168,21,168,168:7:0:6,0,0:1,0,0:7,0,0 0,21,208,21,208,208:7:0:4,0,0:3,0,0:7,0,0 +17 550 . T <*> 0 . DP=32;ADF=22,0;ADR=9,0;AD=31,0;I16=22,9,0,0,1052,37298,0,0,1806,106610,0,0,548,12176,0,0;QS=3,0;MQSB=0.632337;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:12,0:5,0:17,0 0,21,150:7:0:6,0:1,0:7,0 0,21,220:7:0:4,0:3,0:7,0 +17 551 . G <*> 0 . DP=31;ADF=22,0;ADR=9,0;AD=31,0;I16=22,9,0,0,1121,41639,0,0,1806,106610,0,0,541,12045,0,0;QS=3,0;MQSB=0.632337;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:12,0:5,0:17,0 0,21,172:7:0:6,0:1,0:7,0 0,21,208:7:0:4,0:3,0:7,0 +17 552 . C <*> 0 . DP=30;ADF=21,0;ADR=9,0;AD=30,0;I16=21,9,0,0,1093,41365,0,0,1746,103010,0,0,535,11947,0,0;QS=3,0;MQSB=0.636601;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255:16:0:11,0:5,0:16,0 0,21,167:7:0:6,0:1,0:7,0 0,21,208:7:0:4,0:3,0:7,0 +17 553 . A <*> 0 . DP=30;ADF=20,0;ADR=8,0;AD=28,0;I16=20,8,0,0,981,35387,0,0,1626,95810,0,0,485,10831,0,0;QS=3,0;MQSB=0.596163;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,45,255:15:0:10,0:5,0:15,0 0,18,150:6:0:5,0:1,0:6,0 0,21,194:7:0:5,0:2,0:7,0 +17 554 . A <*> 0 . DP=30;ADF=19,0;ADR=9,0;AD=28,0;I16=19,9,0,0,975,35601,0,0,1626,95810,0,0,488,10906,0,0;QS=3,0;MQSB=0.646113;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,45,255:15:0:10,0:5,0:15,0 0,15,139:5:0:4,0:1,0:5,0 0,24,211:8:0:5,0:3,0:8,0 +17 555 . A <*> 0 . DP=30;ADF=20,0;ADR=10,0;AD=30,0;I16=20,10,0,0,1024,36526,0,0,1746,103010,0,0,514,11392,0,0;QS=3,0;MQSB=0.679025;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:11,0:6,0:17,0 0,18,150:6:0:5,0:1,0:6,0 0,21,211:7:0:4,0:3,0:7,0 +17 556 . C <*> 0 . DP=29;ADF=20,0;ADR=9,0;AD=29,0;I16=20,9,0,0,1055,39195,0,0,1709,101641,0,0,509,11219,0,0;QS=3,0;MQSB=0.894839;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:11,0:6,0:17,0 0,18,158:6:0:5,0:1,0:6,0 0,18,186:6:0:4,0:2,0:6,0 +17 557 . A <*> 0 . DP=27;ADF=18,0;ADR=9,0;AD=27,0;I16=18,9,0,0,987,36749,0,0,1589,94441,0,0,506,11074,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,45,255:15:0:9,0:6,0:15,0 0,18,157:6:0:5,0:1,0:6,0 0,18,186:6:0:4,0:2,0:6,0 +17 558 . A <*> 0 . DP=27;ADF=18,0;ADR=8,0;AD=26,0;I16=18,8,0,0,948,35808,0,0,1560,93600,0,0,477,10281,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,45,255:15:0:9,0:6,0:15,0 0,15,143:5:0:5,0:0,0:5,0 0,18,177:6:0:4,0:2,0:6,0 +17 559 . C A,<*> 0 . DP=27;ADF=17,0,0;ADR=8,1,0;AD=25,1,0;I16=17,8,0,1,908,33726,14,196,1500,90000,29,841,448,9516,25,625;QS=2.92708,0.0729167,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.90038;BQB=1;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,42,255,42,255,255:14:0:8,0,0:6,0,0:14,0,0 0,4,116,15,119,123:6:0:5,0,0:0,1,0:5,1,0 0,18,169,18,169,169:6:0:4,0,0:2,0,0:6,0,0 +17 560 . C <*> 0 . DP=28;ADF=19,0;ADR=9,0;AD=28,0;I16=19,9,0,0,992,36552,0,0,1649,98041,0,0,494,10654,0,0;QS=3,0;MQSB=0.896555;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,45,255:15:0:9,0:6,0:15,0 0,18,160:6:0:5,0:1,0:6,0 0,21,181:7:0:5,0:2,0:7,0 +17 561 . A <*> 0 . DP=28;ADF=18,0;ADR=9,0;AD=27,0;I16=18,9,0,0,963,35455,0,0,1589,94441,0,0,466,9946,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,42,255:14:0:8,0:6,0:14,0 0,18,158:6:0:5,0:1,0:6,0 0,21,194:7:0:5,0:2,0:7,0 +17 562 . C <*> 0 . DP=28;ADF=18,0;ADR=9,0;AD=27,0;I16=18,9,0,0,1006,38392,0,0,1589,94441,0,0,463,9893,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,42,255:14:0:8,0:6,0:14,0 0,18,153:6:0:5,0:1,0:6,0 0,21,187:7:0:5,0:2,0:7,0 +17 563 . A <*> 0 . DP=27;ADF=17,0;ADR=9,0;AD=26,0;I16=17,9,0,0,893,32413,0,0,1529,90841,0,0,460,9820,0,0;QS=3,0;MQSB=0.90038;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,42,255:14:0:8,0:6,0:14,0 0,15,149:5:0:4,0:1,0:5,0 0,21,179:7:0:5,0:2,0:7,0 +17 564 . C <*> 0 . DP=27;ADF=18,0;ADR=9,0;AD=27,0;I16=18,9,0,0,859,28747,0,0,1589,94441,0,0,482,10402,0,0;QS=3,0;MQSB=0.898397;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,45,255:15:0:9,0:6,0:15,0 0,15,121:5:0:4,0:1,0:5,0 0,21,182:7:0:5,0:2,0:7,0 +17 565 . G <*> 0 . DP=30;ADF=17,0;ADR=9,0;AD=26,0;I16=17,9,0,0,818,26928,0,0,1560,93600,0,0,454,9764,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,45,255:15:0:9,0:6,0:15,0 0,12,96:4:0:3,0:1,0:4,0 0,21,154:7:0:5,0:2,0:7,0 +17 566 . C <*> 0 . DP=29;ADF=15,0;ADR=11,0;AD=26,0;I16=15,11,0,0,903,33405,0,0,1529,90841,0,0,424,9084,0,0;QS=3,0;MQSB=0.927041;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,45,255:15:0:7,0:8,0:15,0 0,15,155:5:0:3,0:2,0:5,0 0,18,167:6:0:5,0:1,0:6,0 +17 567 . C <*> 0 . DP=30;ADF=15,0;ADR=12,0;AD=27,0;I16=15,12,0,0,932,33774,0,0,1589,94441,0,0,462,10178,0,0;QS=3,0;MQSB=0.935229;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,45,255:15:0:7,0:8,0:15,0 0,15,155:5:0:3,0:2,0:5,0 0,21,196:7:0:5,0:2,0:7,0 +17 568 . C <*> 0 . DP=29;ADF=15,0;ADR=13,0;AD=28,0;I16=15,13,0,0,1057,40817,0,0,1649,98041,0,0,482,10438,0,0;QS=3,0;MQSB=0.942064;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255:16:0:8,0:8,0:16,0 0,18,183:6:0:3,0:3,0:6,0 0,18,189:6:0:4,0:2,0:6,0 +17 569 . T <*> 0 . DP=30;ADF=16,0;ADR=12,0;AD=28,0;I16=16,12,0,0,1056,41296,0,0,1649,98041,0,0,493,10655,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,45,255:15:0:8,0:7,0:15,0 0,18,190:6:0:3,0:3,0:6,0 0,21,213:7:0:5,0:2,0:7,0 +17 570 . T <*> 0 . DP=30;ADF=16,0;ADR=12,0;AD=28,0;I16=16,12,0,0,954,34972,0,0,1680,100800,0,0,472,10086,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255:16:0:8,0:8,0:16,0 0,15,157:5:0:3,0:2,0:5,0 0,21,195:7:0:5,0:2,0:7,0 +17 571 . C <*> 0 . DP=31;ADF=17,0;ADR=12,0;AD=29,0;I16=17,12,0,0,1061,40675,0,0,1740,104400,0,0,472,10158,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:9,0:8,0:17,0 0,15,155:5:0:3,0:2,0:5,0 0,21,193:7:0:5,0:2,0:7,0 +17 572 . A <*> 0 . DP=31;ADF=18,0;ADR=12,0;AD=30,0;I16=18,12,0,0,1102,42642,0,0,1769,105241,0,0,499,10887,0,0;QS=3,0;MQSB=0.929991;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:9,0:8,0:17,0 0,21,203:7:0:4,0:3,0:7,0 0,18,175:6:0:5,0:1,0:6,0 +17 573 . A <*> 0 . DP=31;ADF=18,0;ADR=12,0;AD=30,0;I16=18,12,0,0,1057,38473,0,0,1769,105241,0,0,501,10975,0,0;QS=3,0;MQSB=0.929991;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:9,0:8,0:17,0 0,21,199:7:0:4,0:3,0:7,0 0,18,178:6:0:5,0:1,0:6,0 +17 574 . C A,<*> 0 . DP=31;ADF=18,0,0;ADR=11,1,0;AD=29,1,0;I16=18,11,0,1,1088,41328,15,225,1740,104400,29,841,478,10422,25,625;QS=2.94071,0.0592885,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.929991;BQB=1;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255,48,255,255:16:0:8,0,0:8,0,0:16,0,0 0,9,170,21,173,177:8:0:5,0,0:2,1,0:7,1,0 0,18,173,18,173,173:6:0:5,0,0:1,0,0:6,0,0 +17 575 . T <*> 0 . DP=30;ADF=16,0;ADR=10,0;AD=26,0;I16=16,10,0,0,1024,41260,0,0,1560,93600,0,0,448,9842,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,42,255:14:0:7,0:7,0:14,0 0,21,209:7:0:5,0:2,0:7,0 0,15,163:5:0:4,0:1,0:5,0 +17 576 . G <*> 0 . DP=30;ADF=17,0;ADR=12,0;AD=29,0;I16=17,12,0,0,1047,40077,0,0,1709,101641,0,0,507,11087,0,0;QS=3,0;MQSB=0.931617;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255:16:0:8,0:8,0:16,0 0,24,208:8:0:5,0:3,0:8,0 0,15,151:5:0:4,0:1,0:5,0 +17 577 . G <*> 0 . DP=30;ADF=16,0;ADR=12,0;AD=28,0;I16=16,12,0,0,999,37747,0,0,1649,98041,0,0,489,10755,0,0;QS=3,0;MQSB=0.933359;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,45,255:15:0:7,0:8,0:15,0 0,24,204:8:0:5,0:3,0:8,0 0,15,146:5:0:4,0:1,0:5,0 +17 578 . G <*> 0 . DP=29;ADF=16,0;ADR=13,0;AD=29,0;I16=16,13,0,0,975,34803,0,0,1709,101641,0,0,520,11286,0,0;QS=3,0;MQSB=0.940317;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255:16:0:7,0:9,0:16,0 0,24,198:8:0:5,0:3,0:8,0 0,15,151:5:0:4,0:1,0:5,0 +17 579 . G <*> 0 . DP=30;ADF=15,0;ADR=13,0;AD=28,0;I16=15,13,0,0,1028,38752,0,0,1649,98041,0,0,484,10514,0,0;QS=3,0;MQSB=0.942064;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,48,255:16:0:8,0:8,0:16,0 0,24,224:8:0:4,0:4,0:8,0 0,12,145:4:0:3,0:1,0:4,0 +17 580 . A C,<*> 0 . DP=30;ADF=15,1,0;ADR=14,0,0;AD=29,1,0;I16=15,14,1,0,1060,39178,16,256,1709,101641,60,3600,510,11078,17,289;QS=2.97338,0.0266223,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.946202;BQB=1;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,34,255,48,255,255:17:0:7,1,0:9,0,0:16,1,0 0,24,221,24,221,221:8:0:4,0,0:4,0,0:8,0,0 0,15,155,15,155,155:5:0:4,0,0:1,0,0:5,0,0 +17 581 . A <*> 0 . DP=31;ADF=16,0;ADR=15,0;AD=31,0;I16=16,15,0,0,1083,39215,0,0,1829,108841,0,0,530,11384,0,0;QS=3,0;MQSB=0.951229;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:8,0:10,0:18,0 0,24,223:8:0:4,0:4,0:8,0 0,15,153:5:0:4,0:1,0:5,0 +17 582 . C <*> 0 . DP=31;ADF=15,0;ADR=15,0;AD=30,0;I16=15,15,0,0,1080,39870,0,0,1769,105241,0,0,519,11211,0,0;QS=3,0;MQSB=0.952765;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:7,0:10,0:17,0 0,24,207:8:0:4,0:4,0:8,0 0,15,151:5:0:4,0:1,0:5,0 +17 583 . T <*> 0 . DP=30;ADF=16,0;ADR=14,0;AD=30,0;I16=16,14,0,0,1136,43996,0,0,1769,105241,0,0,539,11523,0,0;QS=3,0;MQSB=0.946202;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:8,0:9,0:17,0 0,24,238:8:0:4,0:4,0:8,0 0,15,163:5:0:4,0:1,0:5,0 +17 584 . C <*> 0 . DP=31;ADF=16,0;ADR=13,0;AD=29,0;I16=16,13,0,0,1051,39351,0,0,1709,101641,0,0,499,10619,0,0;QS=3,0;MQSB=0.960189;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:8,0:9,0:17,0 0,21,207:7:0:4,0:3,0:7,0 0,15,157:5:0:4,0:1,0:5,0 +17 585 . A <*> 0 . DP=31;ADF=17,0;ADR=14,0;AD=31,0;I16=17,14,0,0,1096,39866,0,0,1798,106082,0,0,549,11751,0,0;QS=3,0;MQSB=0.998229;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:9,0:9,0:18,0 0,24,211:8:0:4,0:4,0:8,0 0,15,157:5:0:4,0:1,0:5,0 +17 586 . T <*> 0 . DP=31;ADF=16,0;ADR=14,0;AD=30,0;I16=16,14,0,0,1081,39839,0,0,1738,102482,0,0,546,11796,0,0;QS=3,0;MQSB=0.999136;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:8,0:9,0:17,0 0,24,212:8:0:4,0:4,0:8,0 0,15,156:5:0:4,0:1,0:5,0 +17 587 . C <*> 0 . DP=31;ADF=17,0;ADR=13,0;AD=30,0;I16=17,13,0,0,1070,39402,0,0,1769,105241,0,0,532,11350,0,0;QS=3,0;MQSB=0.963674;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:9,0:9,0:18,0 0,21,201:7:0:4,0:3,0:7,0 0,15,155:5:0:4,0:1,0:5,0 +17 588 . A <*> 0 . DP=31;ADF=17,0;ADR=14,0;AD=31,0;I16=17,14,0,0,1126,41642,0,0,1798,106082,0,0,562,12140,0,0;QS=3,0;MQSB=0.998229;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:9,0:9,0:18,0 0,24,222:8:0:4,0:4,0:8,0 0,15,164:5:0:4,0:1,0:5,0 +17 589 . A <*> 0 . DP=31;ADF=17,0;ADR=14,0;AD=31,0;I16=17,14,0,0,1157,43973,0,0,1798,106082,0,0,568,12340,0,0;QS=3,0;MQSB=0.998229;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:9,0:9,0:18,0 0,24,236:8:0:4,0:4,0:8,0 0,15,165:5:0:4,0:1,0:5,0 +17 590 . C <*> 0 . DP=32;ADF=16,0;ADR=14,0;AD=30,0;I16=16,14,0,0,1094,41302,0,0,1769,105241,0,0,549,11951,0,0;QS=3,0;MQSB=0.958545;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:9,0:9,0:18,0 0,18,192:6:0:3,0:3,0:6,0 0,18,175:6:0:4,0:2,0:6,0 +17 591 . A <*> 0 . DP=31;ADF=16,0;ADR=15,0;AD=31,0;I16=16,15,0,0,1165,44163,0,0,1798,106082,0,0,579,12695,0,0;QS=3,0;MQSB=0.999805;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:9,0:9,0:18,0 0,21,209:7:0:3,0:4,0:7,0 0,18,188:6:0:4,0:2,0:6,0 +17 592 . A <*> 0 . DP=31;ADF=15,0;ADR=15,0;AD=30,0;I16=15,15,0,0,1114,42144,0,0,1738,102482,0,0,571,12651,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:8,0:9,0:17,0 0,21,215:7:0:3,0:4,0:7,0 0,18,182:6:0:4,0:2,0:6,0 +17 593 . C <*> 0 . DP=31;ADF=15,0;ADR=14,0;AD=29,0;I16=15,14,0,0,1065,39889,0,0,1709,101641,0,0,550,12132,0,0;QS=3,0;MQSB=0.954405;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:8,0:9,0:17,0 0,18,191:6:0:3,0:3,0:6,0 0,18,174:6:0:4,0:2,0:6,0 +17 594 . A <*> 0 . DP=33;ADF=16,0;ADR=16,0;AD=32,0;I16=16,16,0,0,1163,42917,0,0,1858,109682,0,0,572,12672,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:8,0:9,0:17,0 0,21,205:7:0:3,0:4,0:7,0 0,24,212:8:0:5,0:3,0:8,0 +17 595 . A <*> 0 . DP=33;ADF=17,0;ADR=16,0;AD=33,0;I16=17,16,0,0,1130,39996,0,0,1918,113282,0,0,589,12905,0,0;QS=3,0;MQSB=0.999838;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:9,0:9,0:18,0 0,21,198:7:0:3,0:4,0:7,0 0,24,213:8:0:5,0:3,0:8,0 +17 596 . A <*> 0 . DP=33;ADF=16,0;ADR=16,0;AD=32,0;I16=16,16,0,0,1059,37039,0,0,1858,109682,0,0,590,12952,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:8,0:9,0:17,0 0,21,169:7:0:3,0:4,0:7,0 0,24,230:8:0:5,0:3,0:8,0 +17 597 . C <*> 0 . DP=33;ADF=17,0;ADR=16,0;AD=33,0;I16=17,16,0,0,1196,44890,0,0,1918,113282,0,0,592,12990,0,0;QS=3,0;MQSB=0.999838;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,54,255:18:0:9,0:9,0:18,0 0,21,204:7:0:3,0:4,0:7,0 0,24,220:8:0:5,0:3,0:8,0 +17 598 . T <*> 0 . DP=33;ADF=16,0;ADR=16,0;AD=32,0;I16=16,16,0,0,1214,47104,0,0,1858,109682,0,0,593,13013,0,0;QS=3,0;MQSB=1;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:8,0:9,0:17,0 0,21,217:7:0:3,0:4,0:7,0 0,24,239:8:0:5,0:3,0:8,0 +17 599 . T <*> 0 . DP=33;ADF=16,0;ADR=17,0;AD=33,0;I16=16,17,0,0,1183,43669,0,0,1918,113282,0,0,599,13095,0,0;QS=3,0;MQSB=0.999838;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:8,0:9,0:17,0 0,21,197:7:0:3,0:4,0:7,0 0,27,247:9:0:5,0:4,0:9,0 +17 600 . G <*> 0 . DP=32;ADF=15,0;ADR=17,0;AD=32,0;I16=15,17,0,0,1174,44066,0,0,1858,109682,0,0,601,13145,0,0;QS=3,0;MQSB=0.999287;MQ0F=0 PL:DP:SP:ADF:ADR:AD 0,51,255:17:0:8,0:9,0:17,0 0,21,194:7:0:3,0:4,0:7,0 0,24,232:8:0:4,0:4,0:8,0 diff --git a/test/mpileup/mpileup.6.out b/test/mpileup/mpileup.6.out new file mode 100644 index 0000000..511652e --- /dev/null +++ b/test/mpileup/mpileup.6.out @@ -0,0 +1,65 @@ +##fileformat=VCFv4.2 +##FILTER= +##contig= +##ALT= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT HG00100 HG00101 HG00102 +17 100 . C <*> . . END=117;MinDP=2;QS=3,0 PL:DP 0,24,178:8 0,6,85:2 0,12,118:4 +17 118 . G <*> . . MinDP=1;QS=3,0 PL:DP 0,27,175:9 0,3,60:1 0,21,162:7 +17 119 . G <*> . . END=173;MinDP=2;QS=3,0 PL:DP 0,15,106:5 0,6,73:2 0,12,97:4 +17 174 . G <*> . . END=188;MinDP=1;QS=3,0 PL:DP 0,15,111:5 0,3,27:1 0,15,138:5 +17 189 . C <*> . . END=255;MinDP=2;QS=3,0 PL:DP 0,18,136:6 0,6,45:2 0,9,59:3 +17 256 . A <*> . . END=258;MinDP=5;QS=3,0 PL:DP 0,33,247:11 0,15,110:5 0,18,155:6 +17 259 . C <*> . . MinDP=4;QS=3,0 PL:DP 0,33,255:11 0,12,90:4 0,18,170:6 +17 260 . T <*> . . END=265;MinDP=5;QS=3,0 PL:DP 0,33,254:11 0,15,98:5 0,15,122:5 +17 266 . G <*> . . END=267;MinDP=4;QS=3,0 PL:DP 0,33,254:11 0,12,97:4 0,15,138:5 +17 268 . T <*> . . MinDP=5;QS=3,0 PL:DP 0,33,238:11 0,15,110:5 0,15,156:5 +17 269 . C <*> . . END=270;MinDP=4;QS=3,0 PL:DP 0,36,255:12 0,12,91:4 0,15,143:5 +17 271 . T <*> . . MinDP=5;QS=3,0 PL:DP 0,36,255:12 0,15,113:5 0,15,152:5 +17 272 . C <*> . . END=283;MinDP=4;QS=3,0 PL:DP 0,30,238:10 0,12,95:4 0,12,119:4 +17 284 . T <*> . . END=301;MinDP=5;QS=3,0 PL:DP 0,30,231:10 0,18,119:6 0,15,126:5 +17 302 . T TA 0 . INDEL;IDV=7;IMF=1;DP=25;I16=2,4,8,11,214,7674,793,33369,236,10564,993,55133,109,2229,377,8629;QS=0.511212,2.48879;VDB=0.27613;SGB=-4.22417;MQSB=0.0443614;MQ0F=0 PL:DP:DV 167,0,96:11:6 157,0,9:7:6 201,21,0:7:7 +17 303 . G <*> . . END=354;MinDP=7;QS=3,0 PL:DP 0,27,225:9 0,21,183:7 0,21,185:7 +17 355 . G T,<*> 0 . DP=28;I16=14,13,0,1,1001,37907,41,1681,1442,81174,60,3600,547,12487,25,625;QS=2.875,0.125,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.450096;BQB=1;MQ0F=0 PL:DP:DV 14,0,200,38,203,231:9:1 0,27,222,27,222,222:9:0 0,30,255,30,255,255:10:0 +17 356 . G <*> . . END=374;MinDP=7;QS=3,0 PL:DP 0,27,228:9 0,21,187:7 0,27,251:9 +17 375 . A T,<*> 0 . DP=31;I16=17,13,0,1,1138,43798,14,196,1676,96964,60,3600,547,12177,4,16;QS=2.9661,0.0338983,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.763662;BQB=1;MQ0F=0 PL:DP:DV 0,36,255,36,255,255:12:0 0,24,218,24,218,218:8:0 0,18,255,30,255,255:11:1 +17 376 . G <*> . . END=404;MinDP=5;QS=3,0 PL:DP 0,33,255:11 0,15,131:5 0,30,255:10 +17 405 . T <*> . . END=411;MinDP=3;QS=3,0 PL:DP 0,39,255:13 0,9,103:3 0,30,244:10 +17 412 . C T,<*> 0 . DP=30;I16=17,12,1,0,1094,42458,14,196,1678,98882,60,3600,495,10659,25,625;QS=2.97455,0.0254545,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.991968;BQB=1;MQ0F=0 PL:DP:DV 0,30,255,42,255,255:15:1 0,12,124,12,124,124:4:0 0,33,255,33,255,255:11:0 +17 413 . A <*> . . END=464;MinDP=2;QS=3,0 PL:DP 0,42,255:14 0,6,90:2 0,21,221:7 +17 465 . C <*> . . END=511;MinDP=5;QS=3,0 PL:DP 0,51,255:17 0,15,131:5 0,24,221:8 +17 512 . A C,<*> 0 . DP=33;I16=22,10,0,1,1121,40793,13,169,1866,110210,60,3600,628,14340,9,81;QS=2.97719,0.022807,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.981935;BQB=1;MQ0F=0 PL:DP:DV 0,39,255,51,255,255:18:1 0,21,183,21,183,183:7:0 0,24,231,24,231,231:8:0 +17 513 . A <*> . . MinDP=6;QS=3,0 PL:DP 0,48,255:16 0,18,175:6 0,24,233:8 +17 514 . A T,<*> 0 . DP=32;I16=20,9,0,1,1066,40004,16,256,1686,99410,60,3600,586,13500,11,121;QS=2.97075,0.0292505,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.980594;BQB=1;MQ0F=0 PL:DP:DV 0,31,255,45,255,255:16:1 0,18,171,18,171,171:6:0 0,24,235,24,235,235:8:0 +17 515 . C <*> . . END=522;MinDP=5;QS=3,0 PL:DP 0,42,255:14 0,18,167:6 0,15,170:5 +17 523 . T G,<*> 0 . DP=32;I16=23,8,1,0,1184,45708,15,225,1837,109369,60,3600,626,14446,25,625;QS=2.9794,0.0206044,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.872525;BQB=1;MQ0F=0 PL:DP:DV 0,44,255,57,255,255:20:1 0,21,191,21,191,191:7:0 0,15,166,15,166,166:5:0 +17 524 . T <*> . . END=526;MinDP=4;QS=3,0 PL:DP 0,60,255:20 0,21,185:7 0,12,129:4 +17 527 . A <*> . . END=548;MinDP=5;QS=3,0 PL:DP 0,48,255:16 0,18,169:6 0,15,150:5 +17 549 . T G,<*> 0 . DP=32;I16=22,8,0,1,1101,40987,20,400,1746,103010,60,3600,530,11716,25,625;QS=2.96748,0.0325203,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.632337;BQB=1;MQ0F=0 PL:DP:DV 0,31,255,48,255,255:17:1 0,21,168,21,168,168:7:0 0,21,208,21,208,208:7:0 +17 550 . T <*> . . END=558;MinDP=5;QS=3,0 PL:DP 0,45,255:15 0,15,139:5 0,18,177:6 +17 559 . C A,<*> 0 . DP=27;I16=17,8,0,1,908,33726,14,196,1500,90000,29,841,448,9516,25,625;QS=2.92708,0.0729167,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.90038;BQB=1;MQ0F=0 PL:DP:DV 0,42,255,42,255,255:14:0 0,4,116,15,119,123:6:1 0,18,169,18,169,169:6:0 +17 560 . C <*> . . END=564;MinDP=5;QS=3,0 PL:DP 0,42,255:14 0,15,121:5 0,21,179:7 +17 565 . G <*> . . MinDP=4;QS=3,0 PL:DP 0,45,255:15 0,12,96:4 0,21,154:7 +17 566 . C <*> . . END=573;MinDP=5;QS=3,0 PL:DP 0,45,255:15 0,15,155:5 0,18,167:6 +17 574 . C A,<*> 0 . DP=31;I16=18,11,0,1,1088,41328,15,225,1740,104400,29,841,478,10422,25,625;QS=2.94071,0.0592885,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.929991;BQB=1;MQ0F=0 PL:DP:DV 0,48,255,48,255,255:16:0 0,9,170,21,173,177:8:1 0,18,173,18,173,173:6:0 +17 575 . T <*> . . END=578;MinDP=5;QS=3,0 PL:DP 0,42,255:14 0,21,209:7 0,15,146:5 +17 579 . G <*> . . MinDP=4;QS=3,0 PL:DP 0,48,255:16 0,24,224:8 0,12,145:4 +17 580 . A C,<*> 0 . DP=30;I16=15,14,1,0,1060,39178,16,256,1709,101641,60,3600,510,11078,17,289;QS=2.97338,0.0266223,0;SGB=-0.556633;RPB=1;MQB=1;MQSB=0.946202;BQB=1;MQ0F=0 PL:DP:DV 0,34,255,48,255,255:17:1 0,24,221,24,221,221:8:0 0,15,155,15,155,155:5:0 +17 581 . A <*> . . END=600;MinDP=5;QS=3,0 PL:DP 0,51,255:17 0,18,191:6 0,15,151:5 diff --git a/test/mpileup/mpileup.7.out b/test/mpileup/mpileup.7.out new file mode 100644 index 0000000..75e7fc9 --- /dev/null +++ b/test/mpileup/mpileup.7.out @@ -0,0 +1,70 @@ +##fileformat=VCFv4.2 +##FILTER= +##contig= +##ALT= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##FORMAT= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT HG00101 HG00102 +17 100 . C <*> 0 . DP=9;I16=8,0,0,0,338,15668,0,0,449,26041,0,0,173,4019,0,0;QS=2,0;MQ0F=0 PL 0,9,108 0,15,134 +17 101 . C <*> 0 . DP=9;I16=8,0,0,0,319,14829,0,0,449,26041,0,0,172,3954,0,0;QS=2,0;MQ0F=0 PL 0,9,99 0,15,132 +17 102 . C <*> 0 . DP=9;I16=8,0,0,0,346,16476,0,0,449,26041,0,0,171,3895,0,0;QS=2,0;MQ0F=0 PL 0,9,111 0,15,139 +17 103 . T <*> 0 . DP=9;I16=8,0,0,0,354,17694,0,0,449,26041,0,0,170,3842,0,0;QS=2,0;MQ0F=0 PL 0,9,108 0,15,147 +17 104 . G <*> 0 . DP=9;I16=7,0,0,0,301,14499,0,0,420,25200,0,0,143,3121,0,0;QS=2,0;MQ0F=0 PL 0,6,89 0,15,133 +17 105 . G <*> 0 . DP=9;I16=8,0,0,0,298,12944,0,0,449,26041,0,0,166,3658,0,0;QS=2,0;MQ0F=0 PL 0,9,97 0,15,125 +17 106 . G <*> 0 . DP=9;I16=7,0,0,0,273,12195,0,0,420,25200,0,0,139,2953,0,0;QS=2,0;MQ0F=0 PL 0,6,85 0,15,124 +17 107 . C <*> 0 . DP=9;I16=8,0,0,0,330,15206,0,0,449,26041,0,0,162,3506,0,0;QS=2,0;MQ0F=0 PL 0,9,108 0,15,136 +17 108 . C <*> 0 . DP=9;I16=8,0,0,0,334,15764,0,0,449,26041,0,0,159,3393,0,0;QS=2,0;MQ0F=0 PL 0,9,108 0,15,135 +17 109 . T <*> 0 . DP=9;I16=8,0,0,0,374,19190,0,0,449,26041,0,0,156,3290,0,0;QS=2,0;MQ0F=0 PL 0,9,110 0,15,150 +17 110 . G <*> 0 . DP=9;I16=8,0,0,0,335,16083,0,0,449,26041,0,0,153,3197,0,0;QS=2,0;MQ0F=0 PL 0,9,104 0,15,136 +17 111 . G <*> 0 . DP=9;I16=6,0,0,0,268,13602,0,0,360,21600,0,0,107,2151,0,0;QS=2,0;MQ0F=0 PL 0,6,88 0,12,118 +17 112 . C <*> 0 . DP=9;I16=8,0,0,0,318,15164,0,0,449,26041,0,0,145,2945,0,0;QS=2,0;MQ0F=0 PL 0,9,95 0,15,135 +17 113 . A <*> 0 . DP=9;I16=7,0,0,0,311,15545,0,0,420,25200,0,0,116,2212,0,0;QS=2,0;MQ0F=0 PL 0,6,87 0,15,139 +17 114 . C <*> 0 . DP=9;I16=8,0,0,0,327,15347,0,0,449,26041,0,0,137,2741,0,0;QS=2,0;MQ0F=0 PL 0,9,103 0,15,133 +17 115 . C <*> 0 . DP=11;I16=8,0,0,0,341,16381,0,0,480,28800,0,0,108,2032,0,0;QS=2,0;MQ0F=0 PL 0,6,89 0,18,147 +17 116 . A <*> 0 . DP=11;I16=8,1,0,0,376,18032,0,0,509,29641,0,0,107,1965,0,0;QS=2,0;MQSB=1;MQ0F=0 PL 0,6,90 0,21,175 +17 117 . G <*> 0 . DP=11;I16=8,1,0,0,370,17312,0,0,509,29641,0,0,105,1913,0,0;QS=2,0;MQSB=1;MQ0F=0 PL 0,6,85 0,21,177 +17 118 . G <*> 0 . DP=11;I16=7,1,0,0,319,14789,0,0,449,26041,0,0,102,1876,0,0;QS=2,0;MQSB=1;MQ0F=0 PL 0,3,60 0,21,162 +17 119 . G <*> 0 . DP=10;I16=8,1,0,0,321,14467,0,0,478,26882,0,0,125,2431,0,0;QS=2,0;MQSB=1;MQ0F=0 PL 0,6,73 0,21,160 +17 120 . A <*> 0 . DP=10;I16=8,1,0,0,361,17053,0,0,478,26882,0,0,123,2373,0,0;QS=2,0;MQSB=1;MQ0F=0 PL 0,6,83 0,21,171 +17 121 . G <*> 0 . DP=10;I16=8,1,0,0,347,15913,0,0,478,26882,0,0,121,2327,0,0;QS=2,0;MQSB=1;MQ0F=0 PL 0,6,80 0,21,168 +17 122 . C <*> 0 . DP=11;I16=9,1,0,0,396,18360,0,0,538,30482,0,0,119,2293,0,0;QS=2,0;MQSB=1;MQ0F=0 PL 0,9,99 0,21,178 +17 123 . T <*> 0 . DP=10;I16=8,1,0,0,387,19215,0,0,478,26882,0,0,119,2271,0,0;QS=2,0;MQSB=1;MQ0F=0 PL 0,9,112 0,18,166 +17 124 . T <*> 0 . DP=10;I16=8,1,0,0,350,15768,0,0,478,26882,0,0,119,2261,0,0;QS=2,0;MQSB=1;MQ0F=0 PL 0,9,104 0,18,154 +17 125 . A <*> 0 . DP=10;I16=8,1,0,0,358,16494,0,0,478,26882,0,0,118,2214,0,0;QS=2,0;MQSB=1;MQ0F=0 PL 0,9,104 0,18,162 +17 126 . A <*> 0 . DP=10;I16=8,1,0,0,373,17399,0,0,478,26882,0,0,117,2181,0,0;QS=2,0;MQSB=1;MQ0F=0 PL 0,9,107 0,18,174 +17 127 . C <*> 0 . DP=10;I16=8,1,0,0,366,16632,0,0,478,26882,0,0,116,2162,0,0;QS=2,0;MQSB=1;MQ0F=0 PL 0,9,109 0,18,160 +17 128 . A <*> 0 . DP=10;I16=8,1,0,0,378,17674,0,0,478,26882,0,0,115,2157,0,0;QS=2,0;MQSB=1;MQ0F=0 PL 0,9,111 0,18,162 +17 129 . A <*> 0 . DP=9;I16=7,1,0,0,354,17046,0,0,418,23282,0,0,115,2165,0,0;QS=2,0;MQSB=1;MQ0F=0 PL 0,9,113 0,15,159 +17 130 . A <*> 0 . DP=9;I16=7,1,0,0,349,16363,0,0,418,23282,0,0,115,2185,0,0;QS=2,0;MQSB=1;MQ0F=0 PL 0,9,113 0,15,152 +17 131 . C <*> 0 . DP=9;I16=7,1,0,0,330,14822,0,0,418,23282,0,0,115,2217,0,0;QS=2,0;MQSB=1;MQ0F=0 PL 0,9,110 0,15,147 +17 132 . A <*> 0 . DP=9;I16=7,1,0,0,348,16432,0,0,418,23282,0,0,115,2261,0,0;QS=2,0;MQSB=1;MQ0F=0 PL 0,9,110 0,15,151 +17 133 . T <*> 0 . DP=8;I16=6,2,0,0,315,12451,0,0,418,23282,0,0,141,2941,0,0;QS=2,0;MQSB=0.666667;MQ0F=0 PL 0,9,105 0,15,150 +17 134 . C <*> 0 . DP=8;I16=6,2,0,0,314,12374,0,0,418,23282,0,0,142,3006,0,0;QS=2,0;MQSB=0.666667;MQ0F=0 PL 0,9,105 0,15,152 +17 135 . T <*> 0 . DP=8;I16=6,2,0,0,314,12470,0,0,418,23282,0,0,143,3081,0,0;QS=2,0;MQSB=0.666667;MQ0F=0 PL 0,9,106 0,15,156 +17 136 . G <*> 0 . DP=8;I16=6,2,0,0,291,10787,0,0,418,23282,0,0,145,3165,0,0;QS=2,0;MQSB=0.666667;MQ0F=0 PL 0,9,105 0,15,134 +17 137 . T <*> 0 . DP=8;I16=6,2,0,0,300,11444,0,0,418,23282,0,0,148,3258,0,0;QS=2,0;MQSB=0.666667;MQ0F=0 PL 0,9,104 0,15,139 +17 138 . C <*> 0 . DP=8;I16=6,2,0,0,300,11542,0,0,418,23282,0,0,150,3312,0,0;QS=2,0;MQSB=0.666667;MQ0F=0 PL 0,9,108 0,15,142 +17 139 . C <*> 0 . DP=8;I16=6,2,0,0,291,10833,0,0,418,23282,0,0,152,3378,0,0;QS=2,0;MQSB=0.666667;MQ0F=0 PL 0,9,106 0,15,143 +17 140 . A <*> 0 . DP=8;I16=6,2,0,0,314,12410,0,0,418,23282,0,0,153,3405,0,0;QS=2,0;MQSB=0.666667;MQ0F=0 PL 0,9,107 0,15,153 +17 141 . G <*> 0 . DP=8;I16=6,2,0,0,295,11151,0,0,418,23282,0,0,153,3391,0,0;QS=2,0;MQSB=0.666667;MQ0F=0 PL 0,9,108 0,15,142 +17 142 . C <*> 0 . DP=8;I16=6,2,0,0,264,9036,0,0,418,23282,0,0,153,3385,0,0;QS=2,0;MQSB=0.666667;MQ0F=0 PL 0,9,97 0,15,129 +17 143 . G <*> 0 . DP=8;I16=5,2,0,0,218,7170,0,0,358,19682,0,0,146,3338,0,0;QS=2,0;MQSB=0.7;MQ0F=0 PL 0,9,95 0,12,97 +17 144 . A <*> 0 . DP=8;I16=6,2,0,0,287,10705,0,0,418,23282,0,0,153,3397,0,0;QS=2,0;MQSB=0.666667;MQ0F=0 PL 0,9,105 0,15,129 +17 145 . A <*> 0 . DP=8;I16=6,2,0,0,294,11200,0,0,418,23282,0,0,153,3415,0,0;QS=2,0;MQSB=0.666667;MQ0F=0 PL 0,9,106 0,15,138 +17 146 . T <*> 0 . DP=8;I16=6,2,0,0,281,10419,0,0,418,23282,0,0,153,3441,0,0;QS=2,0;MQSB=0.666667;MQ0F=0 PL 0,9,103 0,15,128 +17 147 . A <*> 0 . DP=8;I16=6,2,0,0,286,10442,0,0,418,23282,0,0,153,3475,0,0;QS=2,0;MQSB=0.666667;MQ0F=0 PL 0,9,99 0,15,140 +17 148 . C <*> 0 . DP=8;I16=6,2,0,0,301,11401,0,0,418,23282,0,0,152,3466,0,0;QS=2,0;MQSB=0.666667;MQ0F=0 PL 0,9,106 0,15,146 +17 149 . C <*> 0 . DP=8;I16=6,2,0,0,293,10907,0,0,418,23282,0,0,150,3414,0,0;QS=2,0;MQSB=0.666667;MQ0F=0 PL 0,9,109 0,15,140 +17 150 . T <*> 0 . DP=7;I16=5,2,0,0,277,11093,0,0,389,22441,0,0,149,3369,0,0;QS=2,0;MQSB=0.5;MQ0F=0 PL 0,6,84 0,15,152 diff --git a/test/mpileup/mpileup.8.out b/test/mpileup/mpileup.8.out new file mode 100644 index 0000000..c136539 --- /dev/null +++ b/test/mpileup/mpileup.8.out @@ -0,0 +1,70 @@ +##fileformat=VCFv4.2 +##FILTER= +##contig= +##ALT= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##FORMAT= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT HG00100 +17 100 . C <*> 0 . DP=9;I16=9,0,0,0,350,14094,0,0,509,29641,0,0,159,3427,0,0;QS=1,0;MQ0F=0 PL 0,27,189 +17 101 . C <*> 0 . DP=9;I16=9,0,0,0,331,12701,0,0,509,29641,0,0,159,3349,0,0;QS=1,0;MQ0F=0 PL 0,27,182 +17 102 . C <*> 0 . DP=9;I16=9,0,0,0,349,13977,0,0,509,29641,0,0,159,3283,0,0;QS=1,0;MQ0F=0 PL 0,27,188 +17 103 . T <*> 0 . DP=9;I16=8,0,0,0,338,14304,0,0,480,28800,0,0,153,3193,0,0;QS=1,0;MQ0F=0 PL 0,24,189 +17 104 . G <*> 0 . DP=9;I16=8,0,0,0,310,12224,0,0,480,28800,0,0,152,3138,0,0;QS=1,0;MQ0F=0 PL 0,24,178 +17 105 . G <*> 0 . DP=10;I16=9,0,0,0,306,10992,0,0,540,32400,0,0,151,3093,0,0;QS=1,0;MQ0F=0 PL 0,27,170 +17 106 . G <*> 0 . DP=10;I16=10,0,0,0,371,14379,0,0,569,33241,0,0,160,3140,0,0;QS=1,0;MQ0F=0 PL 0,30,190 +17 107 . C <*> 0 . DP=10;I16=9,0,0,0,364,14858,0,0,540,32400,0,0,151,3037,0,0;QS=1,0;MQ0F=0 PL 0,27,192 +17 108 . C <*> 0 . DP=10;I16=9,0,0,0,358,14384,0,0,540,32400,0,0,151,3027,0,0;QS=1,0;MQ0F=0 PL 0,27,190 +17 109 . T <*> 0 . DP=10;I16=9,0,0,0,367,15083,0,0,540,32400,0,0,151,3029,0,0;QS=1,0;MQ0F=0 PL 0,27,195 +17 110 . G <*> 0 . DP=10;I16=9,0,0,0,369,15193,0,0,540,32400,0,0,151,3043,0,0;QS=1,0;MQ0F=0 PL 0,27,194 +17 111 . G <*> 0 . DP=10;I16=10,0,0,0,316,10760,0,0,569,33241,0,0,165,3265,0,0;QS=1,0;MQ0F=0 PL 0,30,167 +17 112 . C <*> 0 . DP=10;I16=9,0,0,0,362,14690,0,0,540,32400,0,0,151,3107,0,0;QS=1,0;MQ0F=0 PL 0,27,191 +17 113 . A <*> 0 . DP=10;I16=9,0,0,0,334,12490,0,0,540,32400,0,0,150,3106,0,0;QS=1,0;MQ0F=0 PL 0,27,176 +17 114 . C <*> 0 . DP=10;I16=9,0,0,0,347,13441,0,0,540,32400,0,0,149,3115,0,0;QS=1,0;MQ0F=0 PL 0,27,182 +17 115 . C <*> 0 . DP=10;I16=10,0,0,0,367,14165,0,0,569,33241,0,0,166,3458,0,0;QS=1,0;MQ0F=0 PL 0,30,189 +17 116 . A <*> 0 . DP=10;I16=9,0,0,0,351,13723,0,0,540,32400,0,0,146,3114,0,0;QS=1,0;MQ0F=0 PL 0,27,183 +17 117 . G <*> 0 . DP=10;I16=9,0,0,0,342,13166,0,0,540,32400,0,0,144,3106,0,0;QS=1,0;MQ0F=0 PL 0,27,183 +17 118 . G <*> 0 . DP=9;I16=9,0,0,0,317,11785,0,0,509,29641,0,0,164,3550,0,0;QS=1,0;MQ0F=0 PL 0,27,175 +17 119 . G <*> 0 . DP=9;I16=8,0,0,0,308,11972,0,0,480,28800,0,0,142,3122,0,0;QS=1,0;MQ0F=0 PL 0,24,175 +17 120 . A <*> 0 . DP=9;I16=8,0,0,0,311,12135,0,0,480,28800,0,0,141,3145,0,0;QS=1,0;MQ0F=0 PL 0,24,175 +17 121 . G <*> 0 . DP=9;I16=8,0,0,0,315,12547,0,0,480,28800,0,0,139,3127,0,0;QS=1,0;MQ0F=0 PL 0,24,181 +17 122 . C <*> 0 . DP=9;I16=8,0,0,0,320,12864,0,0,480,28800,0,0,137,3117,0,0;QS=1,0;MQ0F=0 PL 0,24,181 +17 123 . T <*> 0 . DP=8;I16=7,0,0,0,274,10782,0,0,420,25200,0,0,136,3114,0,0;QS=1,0;MQ0F=0 PL 0,21,167 +17 124 . T <*> 0 . DP=9;I16=9,0,0,0,276,9034,0,0,509,29641,0,0,160,3742,0,0;QS=1,0;MQ0F=0 PL 0,27,154 +17 125 . A <*> 0 . DP=8;I16=7,0,0,0,253,9195,0,0,420,25200,0,0,136,3126,0,0;QS=1,0;MQ0F=0 PL 0,21,154 +17 126 . A <*> 0 . DP=8;I16=8,0,0,0,275,9967,0,0,449,26041,0,0,162,3766,0,0;QS=1,0;MQ0F=0 PL 0,24,162 +17 127 . C <*> 0 . DP=8;I16=8,0,0,0,280,10340,0,0,449,26041,0,0,163,3787,0,0;QS=1,0;MQ0F=0 PL 0,24,163 +17 128 . A <*> 0 . DP=8;I16=8,0,0,0,295,11123,0,0,449,26041,0,0,164,3814,0,0;QS=1,0;MQ0F=0 PL 0,24,169 +17 129 . A <*> 0 . DP=8;I16=8,0,0,0,291,10845,0,0,449,26041,0,0,165,3847,0,0;QS=1,0;MQ0F=0 PL 0,24,168 +17 130 . A <*> 0 . DP=8;I16=8,0,0,0,292,10932,0,0,449,26041,0,0,166,3886,0,0;QS=1,0;MQ0F=0 PL 0,24,169 +17 131 . C <*> 0 . DP=7;I16=7,0,0,0,276,10910,0,0,420,25200,0,0,141,3255,0,0;QS=1,0;MQ0F=0 PL 0,21,167 +17 132 . A <*> 0 . DP=7;I16=7,0,0,0,279,11147,0,0,420,25200,0,0,141,3253,0,0;QS=1,0;MQ0F=0 PL 0,21,169 +17 133 . T <*> 0 . DP=7;I16=7,0,0,0,269,10365,0,0,420,25200,0,0,141,3255,0,0;QS=1,0;MQ0F=0 PL 0,21,163 +17 134 . C <*> 0 . DP=7;I16=7,0,0,0,293,12279,0,0,420,25200,0,0,141,3261,0,0;QS=1,0;MQ0F=0 PL 0,21,177 +17 135 . T <*> 0 . DP=7;I16=7,0,0,0,286,11708,0,0,420,25200,0,0,141,3271,0,0;QS=1,0;MQ0F=0 PL 0,21,173 +17 136 . G <*> 0 . DP=7;I16=7,0,0,0,283,11471,0,0,420,25200,0,0,141,3285,0,0;QS=1,0;MQ0F=0 PL 0,21,172 +17 137 . T <*> 0 . DP=7;I16=7,0,0,0,263,9933,0,0,420,25200,0,0,141,3303,0,0;QS=1,0;MQ0F=0 PL 0,21,160 +17 138 . C <*> 0 . DP=7;I16=7,0,0,0,284,11546,0,0,420,25200,0,0,141,3325,0,0;QS=1,0;MQ0F=0 PL 0,21,172 +17 139 . C <*> 0 . DP=7;I16=7,0,0,0,263,9957,0,0,420,25200,0,0,140,3302,0,0;QS=1,0;MQ0F=0 PL 0,21,161 +17 140 . A <*> 0 . DP=7;I16=7,0,0,0,269,10379,0,0,420,25200,0,0,139,3285,0,0;QS=1,0;MQ0F=0 PL 0,21,163 +17 141 . G <*> 0 . DP=6;I16=6,0,0,0,239,9599,0,0,360,21600,0,0,139,3273,0,0;QS=1,0;MQ0F=0 PL 0,18,158 +17 142 . C <*> 0 . DP=6;I16=6,0,0,0,239,9557,0,0,360,21600,0,0,139,3265,0,0;QS=1,0;MQ0F=0 PL 0,18,157 +17 143 . G <*> 0 . DP=6;I16=6,0,0,0,197,6487,0,0,360,21600,0,0,139,3261,0,0;QS=1,0;MQ0F=0 PL 0,18,128 +17 144 . A <*> 0 . DP=6;I16=6,0,0,0,232,9020,0,0,360,21600,0,0,138,3212,0,0;QS=1,0;MQ0F=0 PL 0,18,152 +17 145 . A <*> 0 . DP=6;I16=6,0,0,0,233,9089,0,0,360,21600,0,0,137,3169,0,0;QS=1,0;MQ0F=0 PL 0,18,153 +17 146 . T <*> 0 . DP=6;I16=6,0,0,0,233,9065,0,0,360,21600,0,0,136,3132,0,0;QS=1,0;MQ0F=0 PL 0,18,152 +17 147 . A <*> 0 . DP=6;I16=6,0,0,0,229,8771,0,0,360,21600,0,0,135,3101,0,0;QS=1,0;MQ0F=0 PL 0,18,150 +17 148 . C <*> 0 . DP=6;I16=6,0,0,0,240,9618,0,0,360,21600,0,0,134,3076,0,0;QS=1,0;MQ0F=0 PL 0,18,157 +17 149 . C <*> 0 . DP=6;I16=6,0,0,0,219,8419,0,0,360,21600,0,0,133,3057,0,0;QS=1,0;MQ0F=0 PL 0,18,148 +17 150 . T <*> 0 . DP=6;I16=6,0,0,0,234,9158,0,0,360,21600,0,0,131,2993,0,0;QS=1,0;MQ0F=0 PL 0,18,153 diff --git a/test/mpileup/mpileup.9.out b/test/mpileup/mpileup.9.out new file mode 100644 index 0000000..56efb51 --- /dev/null +++ b/test/mpileup/mpileup.9.out @@ -0,0 +1,70 @@ +##fileformat=VCFv4.2 +##FILTER= +##contig= +##ALT= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##FORMAT= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT SAMPLE1 SAMPLE2 +17 100 . C <*> 0 . DP=9;I16=8,0,0,0,338,15668,0,0,449,26041,0,0,173,4019,0,0;QS=2,0;MQ0F=0 PL 0,9,108 0,15,134 +17 101 . C <*> 0 . DP=9;I16=8,0,0,0,319,14829,0,0,449,26041,0,0,172,3954,0,0;QS=2,0;MQ0F=0 PL 0,9,99 0,15,132 +17 102 . C <*> 0 . DP=9;I16=8,0,0,0,346,16476,0,0,449,26041,0,0,171,3895,0,0;QS=2,0;MQ0F=0 PL 0,9,111 0,15,139 +17 103 . T <*> 0 . DP=9;I16=8,0,0,0,354,17694,0,0,449,26041,0,0,170,3842,0,0;QS=2,0;MQ0F=0 PL 0,9,108 0,15,147 +17 104 . G <*> 0 . DP=9;I16=7,0,0,0,301,14499,0,0,420,25200,0,0,143,3121,0,0;QS=2,0;MQ0F=0 PL 0,6,89 0,15,133 +17 105 . G <*> 0 . DP=9;I16=8,0,0,0,298,12944,0,0,449,26041,0,0,166,3658,0,0;QS=2,0;MQ0F=0 PL 0,9,97 0,15,125 +17 106 . G <*> 0 . DP=9;I16=7,0,0,0,273,12195,0,0,420,25200,0,0,139,2953,0,0;QS=2,0;MQ0F=0 PL 0,6,85 0,15,124 +17 107 . C <*> 0 . DP=9;I16=8,0,0,0,330,15206,0,0,449,26041,0,0,162,3506,0,0;QS=2,0;MQ0F=0 PL 0,9,108 0,15,136 +17 108 . C <*> 0 . DP=9;I16=8,0,0,0,334,15764,0,0,449,26041,0,0,159,3393,0,0;QS=2,0;MQ0F=0 PL 0,9,108 0,15,135 +17 109 . T <*> 0 . DP=9;I16=8,0,0,0,374,19190,0,0,449,26041,0,0,156,3290,0,0;QS=2,0;MQ0F=0 PL 0,9,110 0,15,150 +17 110 . G <*> 0 . DP=9;I16=8,0,0,0,335,16083,0,0,449,26041,0,0,153,3197,0,0;QS=2,0;MQ0F=0 PL 0,9,104 0,15,136 +17 111 . G <*> 0 . DP=9;I16=6,0,0,0,268,13602,0,0,360,21600,0,0,107,2151,0,0;QS=2,0;MQ0F=0 PL 0,6,88 0,12,118 +17 112 . C <*> 0 . DP=9;I16=8,0,0,0,318,15164,0,0,449,26041,0,0,145,2945,0,0;QS=2,0;MQ0F=0 PL 0,9,95 0,15,135 +17 113 . A <*> 0 . DP=9;I16=7,0,0,0,311,15545,0,0,420,25200,0,0,116,2212,0,0;QS=2,0;MQ0F=0 PL 0,6,87 0,15,139 +17 114 . C <*> 0 . DP=9;I16=8,0,0,0,327,15347,0,0,449,26041,0,0,137,2741,0,0;QS=2,0;MQ0F=0 PL 0,9,103 0,15,133 +17 115 . C <*> 0 . DP=11;I16=8,0,0,0,341,16381,0,0,480,28800,0,0,108,2032,0,0;QS=2,0;MQ0F=0 PL 0,6,89 0,18,147 +17 116 . A <*> 0 . DP=11;I16=8,1,0,0,376,18032,0,0,509,29641,0,0,107,1965,0,0;QS=2,0;MQSB=1;MQ0F=0 PL 0,6,90 0,21,175 +17 117 . G <*> 0 . DP=11;I16=8,1,0,0,370,17312,0,0,509,29641,0,0,105,1913,0,0;QS=2,0;MQSB=1;MQ0F=0 PL 0,6,85 0,21,177 +17 118 . G <*> 0 . DP=11;I16=7,1,0,0,319,14789,0,0,449,26041,0,0,102,1876,0,0;QS=2,0;MQSB=1;MQ0F=0 PL 0,3,60 0,21,162 +17 119 . G <*> 0 . DP=10;I16=8,1,0,0,321,14467,0,0,478,26882,0,0,125,2431,0,0;QS=2,0;MQSB=1;MQ0F=0 PL 0,6,73 0,21,160 +17 120 . A <*> 0 . DP=10;I16=8,1,0,0,361,17053,0,0,478,26882,0,0,123,2373,0,0;QS=2,0;MQSB=1;MQ0F=0 PL 0,6,83 0,21,171 +17 121 . G <*> 0 . DP=10;I16=8,1,0,0,347,15913,0,0,478,26882,0,0,121,2327,0,0;QS=2,0;MQSB=1;MQ0F=0 PL 0,6,80 0,21,168 +17 122 . C <*> 0 . DP=11;I16=9,1,0,0,396,18360,0,0,538,30482,0,0,119,2293,0,0;QS=2,0;MQSB=1;MQ0F=0 PL 0,9,99 0,21,178 +17 123 . T <*> 0 . DP=10;I16=8,1,0,0,387,19215,0,0,478,26882,0,0,119,2271,0,0;QS=2,0;MQSB=1;MQ0F=0 PL 0,9,112 0,18,166 +17 124 . T <*> 0 . DP=10;I16=8,1,0,0,350,15768,0,0,478,26882,0,0,119,2261,0,0;QS=2,0;MQSB=1;MQ0F=0 PL 0,9,104 0,18,154 +17 125 . A <*> 0 . DP=10;I16=8,1,0,0,358,16494,0,0,478,26882,0,0,118,2214,0,0;QS=2,0;MQSB=1;MQ0F=0 PL 0,9,104 0,18,162 +17 126 . A <*> 0 . DP=10;I16=8,1,0,0,373,17399,0,0,478,26882,0,0,117,2181,0,0;QS=2,0;MQSB=1;MQ0F=0 PL 0,9,107 0,18,174 +17 127 . C <*> 0 . DP=10;I16=8,1,0,0,366,16632,0,0,478,26882,0,0,116,2162,0,0;QS=2,0;MQSB=1;MQ0F=0 PL 0,9,109 0,18,160 +17 128 . A <*> 0 . DP=10;I16=8,1,0,0,378,17674,0,0,478,26882,0,0,115,2157,0,0;QS=2,0;MQSB=1;MQ0F=0 PL 0,9,111 0,18,162 +17 129 . A <*> 0 . DP=9;I16=7,1,0,0,354,17046,0,0,418,23282,0,0,115,2165,0,0;QS=2,0;MQSB=1;MQ0F=0 PL 0,9,113 0,15,159 +17 130 . A <*> 0 . DP=9;I16=7,1,0,0,349,16363,0,0,418,23282,0,0,115,2185,0,0;QS=2,0;MQSB=1;MQ0F=0 PL 0,9,113 0,15,152 +17 131 . C <*> 0 . DP=9;I16=7,1,0,0,330,14822,0,0,418,23282,0,0,115,2217,0,0;QS=2,0;MQSB=1;MQ0F=0 PL 0,9,110 0,15,147 +17 132 . A <*> 0 . DP=9;I16=7,1,0,0,348,16432,0,0,418,23282,0,0,115,2261,0,0;QS=2,0;MQSB=1;MQ0F=0 PL 0,9,110 0,15,151 +17 133 . T <*> 0 . DP=8;I16=6,2,0,0,315,12451,0,0,418,23282,0,0,141,2941,0,0;QS=2,0;MQSB=0.666667;MQ0F=0 PL 0,9,105 0,15,150 +17 134 . C <*> 0 . DP=8;I16=6,2,0,0,314,12374,0,0,418,23282,0,0,142,3006,0,0;QS=2,0;MQSB=0.666667;MQ0F=0 PL 0,9,105 0,15,152 +17 135 . T <*> 0 . DP=8;I16=6,2,0,0,314,12470,0,0,418,23282,0,0,143,3081,0,0;QS=2,0;MQSB=0.666667;MQ0F=0 PL 0,9,106 0,15,156 +17 136 . G <*> 0 . DP=8;I16=6,2,0,0,291,10787,0,0,418,23282,0,0,145,3165,0,0;QS=2,0;MQSB=0.666667;MQ0F=0 PL 0,9,105 0,15,134 +17 137 . T <*> 0 . DP=8;I16=6,2,0,0,300,11444,0,0,418,23282,0,0,148,3258,0,0;QS=2,0;MQSB=0.666667;MQ0F=0 PL 0,9,104 0,15,139 +17 138 . C <*> 0 . DP=8;I16=6,2,0,0,300,11542,0,0,418,23282,0,0,150,3312,0,0;QS=2,0;MQSB=0.666667;MQ0F=0 PL 0,9,108 0,15,142 +17 139 . C <*> 0 . DP=8;I16=6,2,0,0,291,10833,0,0,418,23282,0,0,152,3378,0,0;QS=2,0;MQSB=0.666667;MQ0F=0 PL 0,9,106 0,15,143 +17 140 . A <*> 0 . DP=8;I16=6,2,0,0,314,12410,0,0,418,23282,0,0,153,3405,0,0;QS=2,0;MQSB=0.666667;MQ0F=0 PL 0,9,107 0,15,153 +17 141 . G <*> 0 . DP=8;I16=6,2,0,0,295,11151,0,0,418,23282,0,0,153,3391,0,0;QS=2,0;MQSB=0.666667;MQ0F=0 PL 0,9,108 0,15,142 +17 142 . C <*> 0 . DP=8;I16=6,2,0,0,264,9036,0,0,418,23282,0,0,153,3385,0,0;QS=2,0;MQSB=0.666667;MQ0F=0 PL 0,9,97 0,15,129 +17 143 . G <*> 0 . DP=8;I16=5,2,0,0,218,7170,0,0,358,19682,0,0,146,3338,0,0;QS=2,0;MQSB=0.7;MQ0F=0 PL 0,9,95 0,12,97 +17 144 . A <*> 0 . DP=8;I16=6,2,0,0,287,10705,0,0,418,23282,0,0,153,3397,0,0;QS=2,0;MQSB=0.666667;MQ0F=0 PL 0,9,105 0,15,129 +17 145 . A <*> 0 . DP=8;I16=6,2,0,0,294,11200,0,0,418,23282,0,0,153,3415,0,0;QS=2,0;MQSB=0.666667;MQ0F=0 PL 0,9,106 0,15,138 +17 146 . T <*> 0 . DP=8;I16=6,2,0,0,281,10419,0,0,418,23282,0,0,153,3441,0,0;QS=2,0;MQSB=0.666667;MQ0F=0 PL 0,9,103 0,15,128 +17 147 . A <*> 0 . DP=8;I16=6,2,0,0,286,10442,0,0,418,23282,0,0,153,3475,0,0;QS=2,0;MQSB=0.666667;MQ0F=0 PL 0,9,99 0,15,140 +17 148 . C <*> 0 . DP=8;I16=6,2,0,0,301,11401,0,0,418,23282,0,0,152,3466,0,0;QS=2,0;MQSB=0.666667;MQ0F=0 PL 0,9,106 0,15,146 +17 149 . C <*> 0 . DP=8;I16=6,2,0,0,293,10907,0,0,418,23282,0,0,150,3414,0,0;QS=2,0;MQSB=0.666667;MQ0F=0 PL 0,9,109 0,15,140 +17 150 . T <*> 0 . DP=7;I16=5,2,0,0,277,11093,0,0,389,22441,0,0,149,3369,0,0;QS=2,0;MQSB=0.5;MQ0F=0 PL 0,6,84 0,15,152 diff --git a/test/mpileup/mpileup.ref.fa b/test/mpileup/mpileup.ref.fa new file mode 100644 index 0000000..7c2ec2a --- /dev/null +++ b/test/mpileup/mpileup.ref.fa @@ -0,0 +1,71 @@ +>17 17:1-4200 +AAGCTTCTCACCCTGTTCCTGCATAGATAATTGCATGACAATTGCCTTGTCCCTGCTGAA +TGTGCTCTGGGGTCTCTGGGGTCTCACCCACGACCAACTCCCTGGGCCTGGCACCAGGGA +GCTTAACAAACATCTGTCCAGCGAATACCTGCATCCCTAGAAGTGAAGCCACCGCCCAAA +GACACGCCCATGTCCAGCTTAACCTGCATCCCTAGAAGTGAAGGCACCGCCCAAAGACAC +GCCCATGTCCAGCTTATTCTGCCCAGTTCCTCTCCAGAAAGGCTGCATGGTTGACACACA +GTGCCTGCGACAAAGCTGAATGCTATCATTTAAAAACTCCTTGCTGGTTTGAGAGGCAGA +AAATGATATCTCATAGTTGCTTTACTTTGCATATTTTAAAATTGTGACTTTCATGGCATA +AATAATACTGGTTTATTACAGAAGCACTAGAAAATGCATGTGGACAAAAGTTGGGATTAG +GAGAGAGAAATGAAGACATATGTCCACACAAAAACCTGTTCATTGCAGCTTTCTACCATC +ACCAAAAATTGCAAACAACCACACGCCCTTCAACTGGGGAACTCATCAACAACAAACTTG +TGGTTTACCCACACAATGGAAGACCACTTAGCAACAAAAAGGACCAAACTCCTGGTACAT +GCAACTGACAGATGAATCTCAAACGCATTCCTCCGTGTGAAAGAAGCCGGACTCACAGGG +CAACACACTATCTGACTGTTTCATGGGAAAGTCTGGAAACGGCAACACCATTGAGACAGA +AAACAGGTGAGTGGTTGCCTGGGGCCAGGGAACTTTCTGGGGTCATATTCTCTGTGTTGA +TTCTGGTGGTGGAAACAAGACTGTCCCAGCCTGGGTGATACAGCGAGACCCCATCTCTAC +CAAAAAATTAAAAATTAGCTGGGCATGGTGGTGCATGCCTGTAGTCCCAGCTATTCACAG +TGCTGAGGTGGGAAGATGCTTGAGCCCAGGAGTTCAAGGCTGCAATGAGCTATGATTGCG +CCACTGCACTTTGGCCTGGACAACAGAGCAAAACCCTGTCTCTAAAAAAAGAAAAGAAAA +GAAAAACTCACTGGATATGAATGATACAGGTTGAGGATCCATTATCTGAAATGCTTGGAC +CAGATGTTTTGAATTTTGGATTTTTTCATATTTTGTAATCTTTGCAGTATATTTACCAGT +TCAGCATCCCTAACTCAAAAATTCAAAAATCTGAAATCCCAAACGCGCCAATAAGCATTC +CCTTTGAGCGTCATGTCGGTGCTTGGAATGTTTGGGGTTTTGGATTTACAGCTTTGGGAC +GCTCAACCTGTACCTCAATAAACCTGATTTTAAAAAAGTTTGGGGGGATTCCCCTAAGCC +CGCCACCCGGAGACAGCGGATTTCCTTAGTTACTTACTATGCTCCTTGGCCATTTCTCTA +GGTATTGGTATATTGTGTCTGCTGTGAACTGTCCTTGGCCTGTTTGGTGACGGGTGAGGA +GCAGGGACAGAAGGGTCCTGCGTGCCCTGCCTTCACAAGCCCCTGGAAGGAAAGTTGTTT +TGGGATCTCTGCACCCTCAGCCTGGACAACTTGTGCCCATCTGGTGACCCCTCACTCAGC +CACCAGACTTCCACGACAGGCTCCAGCCTCGGCACCTTCAGCCATGGACAGTTCCGCCAG +CGTTGCCCTCTGTTCTGCTGTTTTCTCTACCAGAAGTGCCCTTCCCTCCTCACCTGACCA +CTCTGGGGAAATCCCTCAGCACCCTCCCTGAGCATACCCTACTCTGGCACAAGCCCACCC +TGCAAAGCCCCTGAGGCCCGCCCTGTGGCGTCTCTCCCTCCCTTGCTGTCAGGACAGTGG +TCCTGGCCACCGGGGCTCACGGAGCCGCCCTGTGCCGTGTACCTCTGAGCCCTCTGCACA +GTGCCTTCTGCTTGCCTGTGGCTTTGAGAAGAAACCCCTTCTGGTTATACATAAGACAGC +CAGAGAAGGGAGTTGCCCAGGGTGGCACAGCACGTTGCTGCCAGTTACTGCCATTTTCAC +GGGCATGAAATGGAGATAACAACAGGAGCGACCGCACAGGCTGCTGAGCGCGTCACACGC +AGCCATCGCGCAGCTCAGGGATATTACGTGTAACTCGACATGTCAGCGATTGTCACAGGC +ACTGCTACTCCTGGGGTTTTCCATCAAACCCTCAAGAGCTGGGCCTGGGGTCAACTTCCG +GCCTGGGGAAACTGGGGCAAGTATCACCAGAGATGAGCTTTATAAAAATAATGGTGCTAG +CTGGGCATGGTGGCTTGCACCTGTAATCCCAGCACTTTGGGAGGCCGAGCTAGGAGGATC +GTTTGAGTCCAGCAGTTTGAGACCAGCCTGGCCAATACGGCAAAACCCAGTCTCTACAAA +AAATACAAAAAACAACTAGCCAGGCGTGGTGGTGCACACCTGTAGTCCCAGCTACTCAGG +AGGCTGAGGGGGAAGGACTGCTTGAGCCCAGGAGTTTGAGGCTGCTGTGAGCTGTGATCG +CATCACTGCATTCCAGCCCGGTGACAGAGTGAGTCACTGTCTCAAAAAAGAAAGGAAGAA +ATAAAGAAAACAAATAAAAATAATAGTGCAGACAAAAGGCCTTGACCCATCTAGCTTTGG +CCCTCAGCATCAACCGCTAGATACGTCCCTCCCTTTCTTCTGGGGCACAGGTCACACTCT +CTTCCAGGTCTAGGATGCAGCTGAGGGGTGCCCCTCTTACCATCTAATCTGTGCCCTTAT +TTCCTCTGCTTTAGTGAGGAAGAGGCCCCTGGTCCATGAAGGGGCCTTTCAGAGACGGGG +ACCCCTGAGGAGCCCCGAGCAGCAGCCGTCGTGTCTCACCCAGGGTGTCTGAAACAGATG +TGGAGGTCTCGGGTGAGGCGTGGCTCAGATACAGGGAGTGGCCCACAGCTCGGCCTGTCT +TTGAAAGGCCACGTGACCTGGCCCACGGCTGGCAGGTGGGACCCAGCTGCAGGGGTCCAG +CAGCACCCACAGCAGCCACCTGTGGCAGGGAGGAGCTTGTGGTACAGTGGACAGGCCCTG +CCCAGATGGCCCCCCGCCTGCCTGTGGAAGTTGACCAGACCATCTGTCACAGCAGGTAAG +ACTCTGCTTTCTGGGCAACCCAGCAGGTGACCCTGGAATTCCTGTCCATCTGGCAGGTGG +GCATTGAAACTGGTTTAAAAATGTCACACCATAGGCCGGGCACAGTGGCTCACGCCTGTA +ATCCCAGCCCTTTGGGAGGCCAGGGTGGGTGGATCACTTGAGGTCAGGAGTTCAAGACCA +GCCTGGCCAACATGGTGAAACCCCGTCTACTAAAAATACAAAAATTAGCCTGGCGTGGTG +GCGCATGCCTGTAATCCCAGCTACTTGGGAAGCTGAGGGATGAGAACTGCTTGAACCTGG +GAGGCAGACGTTGCAGTGAGCTGAGATCACGCCACTGCACTCCAGCCTGGGCAACAGAGT +AAGACTCTGTCTCAAAAAAAAAAAAATCACACCATTTTGGCTTCAGATTGCATATCCTCC +TGCAAGGATATATACGCGTGAAATTCAAGTCAATGACAAATCAGAAGAAAAAACATATAT +ATACGCAAACCAGTATCCTACTGTGTGTGTCGTTTGTTGTGTTTTCGACAGCTGTCCGTG +TTATAATAATTCCTCTAGTTCAAATTTATTCATTTTTAACTTCATAGTACCACATTCTAC +ACACTGCCCATGTCCCCTCAAGCTTCCCCTGGCTCCTGCAACCACAAATCTACTCTCTGC +CTCTGTGGGTTGACCTATTCTGGACACGTCATAGAAATAGAGTCCTGCAACACGTGGCCG +TCTGTGTCTGGCTTCTCTCGCTTAGCATCTTGTTTCCAAGGTCCTCCCACAGTGTAGCAT +GCACCTGCTACACTCCTTCTTAGGGCTGATATTCCACGCACCTGCTACACTCCTTCTTAT +GGCTGATATTCCACGCACCTGCTACACTCCTTCTTAGGGCTGATATTCCACACACCCGCT +ACACTCCTTCTTAGGGCTGATATTCCACGCACCCGCTACACTCCTTCTTAGGGCTGATAT +TCCACGCACCTGCTACACTCCTTCTTAGGGCTGATATTCCACGCACCTGCTACACTCCTT +CTTAGGGCTGATATTCCACGCACCTGCTACACTCCTTCTTAGGGCTGATATTCCACGCAC diff --git a/test/mpileup/mpileup.ref.fa.fai b/test/mpileup/mpileup.ref.fa.fai new file mode 100644 index 0000000..c211266 --- /dev/null +++ b/test/mpileup/mpileup.ref.fa.fai @@ -0,0 +1 @@ +17 4200 14 60 61 diff --git a/test/mplp.10.samples b/test/mplp.10.samples new file mode 100644 index 0000000..5d8cc13 --- /dev/null +++ b/test/mplp.10.samples @@ -0,0 +1,5 @@ +ERR162872 +ERR162875 SAMPLE1a +ERR013140 SAMPLE1b +ERR229776 SAMPLE2 +ERR229775 SAMPLE3 diff --git a/test/mplp.11.rgs b/test/mplp.11.rgs new file mode 100644 index 0000000..6e0d343 --- /dev/null +++ b/test/mplp.11.rgs @@ -0,0 +1 @@ +ERR229775 diff --git a/test/mplp.9.samples b/test/mplp.9.samples new file mode 100644 index 0000000..af6b516 --- /dev/null +++ b/test/mplp.9.samples @@ -0,0 +1,2 @@ +HG00101 SAMPLE1 +HG00102 SAMPLE2 diff --git a/test/mplp.samples b/test/mplp.samples new file mode 100644 index 0000000..1a9b396 --- /dev/null +++ b/test/mplp.samples @@ -0,0 +1,2 @@ +HG00101 +HG00102 diff --git a/test/norm.fa b/test/norm.fa new file mode 100644 index 0000000..2eecd7f --- /dev/null +++ b/test/norm.fa @@ -0,0 +1,28 @@ +>20 20:1339000-1339300 +AGGATGGGGCTCATTAATAGAGCTCCACTTGTCTCCAGAATCACTGGTGAGGAAGGGGAG +TGTTGCCCCCACATTCGTGCACAGCAGGGATGGTTCACCGAACTCCACACCAGTCTCTGC +AGAGCCTGTTGGGGAGAGGAGGGCTGTGGTTTCTTTGATGGTGTTCACCTGGAGTAGAGC +AAGTATTGTCAAAAGGGTCATCCTCGGAGGTTGCAGTGAGCCGAGATCGCACCATTGCAC +TGCAGCCTGGGAGACAGAGCAAGACTCCATCTCAAAAAAAAAAAAAAAAAAAAAGGCCAT +C +>1 1:10143-10443 +CTAACCCCTAACCCTAACCCTAACCCTAACCCTAACCTAACCCTAACCCTAACCCTAACC +CTAACCCTAACCCTAACCCTAACCCTAACCCCTAACCCTAACCCTAAACCCTAAACCCTA +ACCCTAACCCTAACCCTAACCCTAACCCCAACCCCAACCCCAACCCCAACCCCAACCCCA +ACCCTAACCCCTAACCCTAACCCTAACCCTACCCTAACCCTAACCCTAACCCTAACCCTA +ACCCTAACCCCTAACCCCTAACCCTAACCCTAACCCTAACCCTAACCCTAACCCTAACCC +>2 1:1382388-1382602 +GGGCGTCTCATAGCTGGAGCAATGGCGAGCGCCTGGACAAGGGAGGGGAAGGGGTTCTTA +TTACTGACGCGGGTAGCCCCTACTGCTGTGTGGTTCCCCTATTTTTTTTTTTTTCTTTTT +GAGACGGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGCACAATCTCGGCTCACTG +CAAGCTCCACCTCCTGGGTTCACGCCATTCTCCTG +>3 madeup +ACTGGACACGTGGACACACACACACACACACACACACACACAGTCAAACCACCTACCAGA +>4 20:8917026-8917085 +TCCCCTCTTGACCTCTCTCTATTTTTTTTTTTTTTTCTGAGATGGATTTTTGCTCTTGTT +>5 20:18724313-18724343 +GTCTCAAAAAAAAAAAAAAAAAAAAGAAAAG +>21 +TTTATTATTATTATTATTAAATTGAATTTATTTAGTGTACATACATTCATGTGTATTGTG +>22 +NNNNNNNNNNNNNNNNNNNNNNNNNNNNNN diff --git a/test/norm.fa.fai b/test/norm.fa.fai new file mode 100644 index 0000000..da3fb85 --- /dev/null +++ b/test/norm.fa.fai @@ -0,0 +1,8 @@ +20 301 23 60 61 +1 300 347 60 61 +2 215 673 60 61 +3 60 902 60 61 +4 60 985 60 61 +5 31 1070 31 32 +21 60 1106 60 61 +22 30 1171 30 31 diff --git a/test/norm.merge.2.out b/test/norm.merge.2.out new file mode 100644 index 0000000..d3c1414 --- /dev/null +++ b/test/norm.merge.2.out @@ -0,0 +1,38 @@ +##fileformat=VCFv4.1 +##FILTER= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##contig= +##contig= +##contig= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##INFO= +##FILTER= +##FILTER= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT XY00001 XY00002 XY00003 +1 105 . T C 999 PASS . GT:FGI:FRI 1:1,2:3,4 0/1:5,6,7:8,9 0/1:.:.,. +1 110 . C A 999 PASS . GT:FGI 1:1,2 0:3,4 0:. +1 150 . A C 999 PASS . GT:FGI 1:1,2 0:. 0:3,4 diff --git a/test/norm.merge.2.vcf b/test/norm.merge.2.vcf new file mode 100644 index 0000000..779551a --- /dev/null +++ b/test/norm.merge.2.vcf @@ -0,0 +1,41 @@ +##fileformat=VCFv4.1 +##FILTER= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##contig= +##contig= +##contig= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##INFO= +##FILTER= +##FILTER= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT XY00001 XY00002 XY00003 +1 105 . T . 999 PASS . GT:FGI:FRI 0:.:. 0/0:.:. 0/1:.:. +1 105 . T C 999 PASS . GT:FGI:FRI 1:1,2:3,4 0/1:5,6,7:8,9 0/1:.:. +1 110 . C . 999 PASS . GT:FGI 0:. 0:. 0:. +1 110 . C A 999 PASS . GT:FGI 1:1,2 0:3,4 0:. +1 150 . A . 999 PASS . GT:FGI 0:. 0:. 0:. +1 150 . A C 999 PASS . GT:FGI 1:1,2 0:. 0:3,4 diff --git a/test/norm.merge.3.out b/test/norm.merge.3.out new file mode 100644 index 0000000..788a427 --- /dev/null +++ b/test/norm.merge.3.out @@ -0,0 +1,34 @@ +##fileformat=VCFv4.2 +##FILTER= +##contig= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT sample_1 sample_2 +11 48245184 . C G . PASS FL=0.34;FLG=0.1,0,0.9;FLA=88.4;FLR=99,88.4;INT=0;INTG=0,1,9;INTA=88;INTR=99,88;F1;ST=alpha;STA=alpha;STR=alpha,beta;STG=alpha,beta,gamma GT:FL:FLG:FLA:FLR:INT:INTG:INTA:INTR:ST:STA:STR:STG 0|0:0.34:0.1,0,0.9:88.4:99,88.4:0:0,1,9:88:99,88:alpha:alpha:alpha,beta:alpha,beta,gamma 0|0:0.34:0.1,0,0.9:88.4:99,88.4:0:0,1,9:88:99,88:alpha:alpha:alpha,beta:alpha,beta,gamma +11 48245185 . C G,T . PASS FL=0.34;FLG=0.1,0,0.9,.,.,.;FLA=88.4,.;FLR=99,88.4,.;INT=0;INTG=0,1,9,.,.,.;INTA=88,.;INTR=99,88,.;F1;ST=alpha;STA=alpha,.;STR=alpha,beta,.;STG=alpha,beta,gamma,.,.,. GT:FL:FLG:FLA:FLR:INT:INTG:INTA:INTR:ST:STA:STR:STG 0|0:0.34:0.1,0,0.9,.,.,.:88.4,.:99,88.4,.:0:0,1,9,.,.,.:88,.:99,88,.:alpha:alpha,.:alpha,beta,.:alpha,beta,gamma,.,.,. 0|0:0.34:0.1,0,0.9,.,.,.:88.4,.:99,88.4,.:0:0,1,9,.,.,.:88,.:99,88,.:alpha:alpha,.:alpha,beta,.:alpha,beta,gamma,.,.,. +11 48245186 . C G,T . PASS FL=0.34;FLA=88.4,88.4;FLR=99,88.4,88.4;INT=0;INTA=88,11;INTR=99,88,11;F1;ST=alpha;STA=alpha,beta;STR=alpha,beta,gamma GT:FL:FLA:FLR:INT:INTA:INTR:ST:STA:STR 0|0:0.34:88.4,11:99,88.4,11:0:88,11:99,88,11:alpha:alpha,beta:alpha,beta,gamma 0|0:0.34:88.4,11:99,88.4,11:0:88,11:99,88,11:alpha:alpha,beta:alpha,beta,gamma +11 48245187 . C G,T . PASS FL=0.34;FLA=88.4,.;FLR=99,88.4,.;INT=0;INTA=88,.;INTR=99,88,.;F1;ST=alpha;STA=alpha,.;STR=alpha,beta,. GT:FL:FLG:FLA:FLR:INT:INTG:INTA:INTR:ST:STA:STR:STG 0:0.34:0.1,0,.:88.4,.:99,88.4,.:0:0,1,.:88,.:99,88,.:alpha:alpha,.:alpha,beta,.:alpha,beta,. 0:0.34:0.1,0,.:88.4,.:99,88.4,.:0:0,1,.:88,.:99,88,.:alpha:alpha,.:alpha,beta,.:alpha,beta,. diff --git a/test/norm.merge.3.vcf b/test/norm.merge.3.vcf new file mode 100644 index 0000000..f2b980a --- /dev/null +++ b/test/norm.merge.3.vcf @@ -0,0 +1,37 @@ +##fileformat=VCFv4.2 +##contig= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT sample_1 sample_2 +11 48245184 . C G . PASS FL=0.34;FLG=0.1,0,0.9;FLA=88.4;FLR=99.0,88.4;INT=0;INTG=0,1,9;INTA=88;INTR=99,88;F1;ST=alpha;STA=alpha;STR=alpha,beta;STG=alpha,beta,gamma GT:FL:FLG:FLA:FLR:INT:INTG:INTA:INTR:ST:STA:STR:STG 0|0:0.34:0.1,0,0.9:88.4:99.0,88.4:0:0,1,9:88:99,88:alpha:alpha:alpha,beta:alpha,beta,gamma 0|0:0.34:0.1,0,0.9:88.4:99.0,88.4:0:0,1,9:88:99,88:alpha:alpha:alpha,beta:alpha,beta,gamma +11 48245184 . C G . PASS . GT 0/0 0/0 +11 48245185 . C G . PASS FL=0.34;FLG=0.1,0,0.9;FLA=88.4;FLR=99.0,88.4;INT=0;INTG=0,1,9;INTA=88;INTR=99,88;F1;ST=alpha;STA=alpha;STR=alpha,beta;STG=alpha,beta,gamma GT:FL:FLG:FLA:FLR:INT:INTG:INTA:INTR:ST:STA:STR:STG 0|0:0.34:0.1,0,0.9:88.4:99.0,88.4:0:0,1,9:88:99,88:alpha:alpha:alpha,beta:alpha,beta,gamma 0|0:0.34:0.1,0,0.9:88.4:99.0,88.4:0:0,1,9:88:99,88:alpha:alpha:alpha,beta:alpha,beta,gamma +11 48245185 . C T . PASS . GT 0/0 0/0 +11 48245186 . C G,T . PASS FL=0.34;FLA=88.4,88.4;FLR=99.0,88.4,88.4;INT=0;INTA=88,11;INTR=99,88,11;F1;ST=alpha;STA=alpha,beta;STR=alpha,beta,gamma GT:FL:FLA:FLR:INT:INTA:INTR:ST:STA:STR 0|0:0.34:88.4,11:99.0,88.4,11:0:88,11:99,88,11:alpha:alpha,beta:alpha,beta,gamma 0|0:0.34:88.4,11:99.0,88.4,11:0:88,11:99,88,11:alpha:alpha,beta:alpha,beta,gamma +11 48245186 . C T . PASS . GT 0/0 0/0 +11 48245187 . C G . PASS FL=0.34;FLA=88.4;FLR=99.0,88.4;INT=0;INTA=88;INTR=99,88;F1;ST=alpha;STA=alpha;STR=alpha,beta GT:FL:FLG:FLA:FLR:INT:INTG:INTA:INTR:ST:STA:STR:STG 0:0.34:0.1,0:88.4:99.0,88.4:0:0,1:88:99,88:alpha:alpha:alpha,beta:alpha,beta 0:0.34:0.1,0:88.4:99.0,88.4:0:0,1:88:99,88:alpha:alpha:alpha,beta:alpha,beta +11 48245187 . C T . PASS . GT 0 0 diff --git a/test/norm.merge.out b/test/norm.merge.out new file mode 100644 index 0000000..449daba --- /dev/null +++ b/test/norm.merge.out @@ -0,0 +1,52 @@ +##fileformat=VCFv4.2 +##FILTER= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##contig= +##contig= +##contig= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##INFO= +##FILTER= +##FILTER= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT XY00001 XY00002 +1 105 . TAAACCCTAAA TAA,TAACCCTAAA 999 PASS INDEL;AN=4;AC=2,2;DP=19;ISTR=SomeString;XRF=1e+06,2e+06,500000;XRI=1111,2222,5555;XRS=AAA,BBB,DDD;XAF=1e+06,500000;XAI=1111,5555;XAS=AAA,DDD;XGF=1e+06,2e+06,3e+06,500000,.,9e+09;XGI=1111,2222,3333,5555,.,9999;XGS=A,B,C,E,.,F GT:PL:DP:FRF:FRI:FRS:FAF:FAI:FAS:FGF:FGI:FGS 1/2:1,2,3,4,.,6:1:1e+06,2e+06,500000:1111,2222,5555:AAAA,BBB,CC:1e+06,500000:1111,5555:A,BB:1e+06,2e+06,3e+06,500000,.,9e+09:1111,2222,3333,5555,.,9999:A,BB,CCC,EEEE,.,FFFFF 1/2:1,2,3,4,.,6:1:1e+06,2e+06,500000:1111,2222,5555:AAAA,BBB,CC:1e+06,500000:1111,5555:A,BB:1e+06,2e+06,3e+06,500000,.,9e+09:1111,2222,3333,5555,.,9999:A,BB,CCC,EEEE,.,FFFFF +2 1 . GGGCGTCTCATAGCTGGAGCAATGGCGAGCGCCTGGACAAGGGAGGGGAAGGGGTTCTTATTACTGACGCGGGTAGCCCCTACTGCTGTGTGGTTCCCCTATTTTTTTTTTTTTCTTTTTGAGACGGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGCACAATCTCGGCTCACTGCAAGCTCCACCT ACGT 999 PASS INDEL;AN=4;AC=2 GT:DP 1/0:1 1/0:1 +2 101 . ATTTTTTTTTTTTT ATTTTTTTTTTTTTTT 999 PASS INDEL;AN=4;AC=4 GT:DP 1/1:1 1/1:1 +2 114 . TC TTCC,TTC 999 FAIL1 INDEL;AN=4;AC=2,2 GT:DP:FGS 1/2:1:A,BB,CCC,EEEE,.,FFFFF 1/2:1:AA,BB,CCC,EEEE,.,FFFFF +2 115 . C T 999 PASS INDEL;AN=4;AC=4 GT:DP 1/1:1 1/1:1 +20 3 . GATG CTATG,GACT 999 PASS INDEL;AN=4;AC=2,2 GT 2/1 2/1 +20 5 id0001;id0002 TGGG TAC,TG,TGGGG,AC . PASS INDEL;AN=4;AC=2,2,0,0 GT:PL:DP 1/2:1,2,3,4,.,6,7,.,.,10,11,.,.,.,15:1 1/2:1,2,3,4,.,6,7,.,.,10,11,.,.,.,15:1 +20 59 id0003 AG . 999 PASS AN=4 GT:PL:DP 0/0:0:4 0/0:0:4 +20 80 . CACAG CACAT 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 +20 81 . A C 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 +20 95 . TCACCG ACACCG 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 +20 95 . TCACCG AAAAAA 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 +20 273 . CAAAAAAAAAAAAAAAAAAAAA CAAAAAAAAAAAAAAAAAAAAAAA,CAAAAAAAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=4;AC=2,2 GT:PL:DP 1/2:0,3,5,3,.,5:1 1/2:0,3,5,3,.,5:1 +20 274 . AAAAAAAAA AAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=0;AC=0 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 +20 275 . A C,G 0 FAIL1;FAIL2 INDEL;AN=2;AC=0,2 GT:PL:DP:FGF:FGI:FGS:FSTR 2:0,0,0:0:1e+06,2e+06,3e+06:1111,2222,3333:A,BB,CCC:WORD 2:0,0,0:0:1e+06,2e+06,3e+06:1111,2222,3333:A,BB,CCC:WORD +20 278 . AAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=0;AC=0 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 +20 300 . A C,G 999 PASS INDEL;AN=0;AC=0,0 GT:PL:DP ./.:0,0,0,0,.,0:0 ./.:0,0,0,0,.,0:0 diff --git a/test/norm.merge.strict.out b/test/norm.merge.strict.out new file mode 100644 index 0000000..92f6f88 --- /dev/null +++ b/test/norm.merge.strict.out @@ -0,0 +1,52 @@ +##fileformat=VCFv4.2 +##FILTER= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##contig= +##contig= +##contig= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##INFO= +##FILTER= +##FILTER= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT XY00001 XY00002 +1 105 . TAAACCCTAAA TAA,TAACCCTAAA 999 PASS INDEL;AN=4;AC=2,2;DP=19;ISTR=SomeString;XRF=1e+06,2e+06,500000;XRI=1111,2222,5555;XRS=AAA,BBB,DDD;XAF=1e+06,500000;XAI=1111,5555;XAS=AAA,DDD;XGF=1e+06,2e+06,3e+06,500000,.,9e+09;XGI=1111,2222,3333,5555,.,9999;XGS=A,B,C,E,.,F GT:PL:DP:FRF:FRI:FRS:FAF:FAI:FAS:FGF:FGI:FGS 1/2:1,2,3,4,.,6:1:1e+06,2e+06,500000:1111,2222,5555:AAAA,BBB,CC:1e+06,500000:1111,5555:A,BB:1e+06,2e+06,3e+06,500000,.,9e+09:1111,2222,3333,5555,.,9999:A,BB,CCC,EEEE,.,FFFFF 1/2:1,2,3,4,.,6:1:1e+06,2e+06,500000:1111,2222,5555:AAAA,BBB,CC:1e+06,500000:1111,5555:A,BB:1e+06,2e+06,3e+06,500000,.,9e+09:1111,2222,3333,5555,.,9999:A,BB,CCC,EEEE,.,FFFFF +2 1 . GGGCGTCTCATAGCTGGAGCAATGGCGAGCGCCTGGACAAGGGAGGGGAAGGGGTTCTTATTACTGACGCGGGTAGCCCCTACTGCTGTGTGGTTCCCCTATTTTTTTTTTTTTCTTTTTGAGACGGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGCACAATCTCGGCTCACTGCAAGCTCCACCT ACGT 999 PASS INDEL;AN=4;AC=2 GT:DP 1/0:1 1/0:1 +2 101 . ATTTTTTTTTTTTT ATTTTTTTTTTTTTTT 999 PASS INDEL;AN=4;AC=4 GT:DP 1/1:1 1/1:1 +2 114 . TC TTCC,TTC 999 PASS INDEL;AN=4;AC=2,2 GT:DP:FGS 1/2:1:A,BB,CCC,EEEE,.,FFFFF 1/2:1:AA,BB,CCC,EEEE,.,FFFFF +2 115 . C T 999 PASS INDEL;AN=4;AC=4 GT:DP 1/1:1 1/1:1 +20 3 . GATG CTATG,GACT 999 PASS INDEL;AN=4;AC=2,2 GT 2/1 2/1 +20 5 id0001;id0002 TGGG TAC,TG,TGGGG,AC . PASS INDEL;AN=4;AC=2,2,0,0 GT:PL:DP 1/2:1,2,3,4,.,6,7,.,.,10,11,.,.,.,15:1 1/2:1,2,3,4,.,6,7,.,.,10,11,.,.,.,15:1 +20 59 id0003 AG . 999 PASS AN=4 GT:PL:DP 0/0:0:4 0/0:0:4 +20 80 . CACAG CACAT 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 +20 81 . A C 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 +20 95 . TCACCG ACACCG 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 +20 95 . TCACCG AAAAAA 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 +20 273 . CAAAAAAAAAAAAAAAAAAAAA CAAAAAAAAAAAAAAAAAAAAAAA,CAAAAAAAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=4;AC=2,2 GT:PL:DP 1/2:0,3,5,3,.,5:1 1/2:0,3,5,3,.,5:1 +20 274 . AAAAAAAAA AAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=0;AC=0 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 +20 275 . A C,G 0 FAIL1;FAIL2 INDEL;AN=2;AC=0,2 GT:PL:DP:FGF:FGI:FGS:FSTR 2:0,0,0:0:1e+06,2e+06,3e+06:1111,2222,3333:A,BB,CCC:WORD 2:0,0,0:0:1e+06,2e+06,3e+06:1111,2222,3333:A,BB,CCC:WORD +20 278 . AAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=0;AC=0 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 +20 300 . A C,G 999 PASS INDEL;AN=0;AC=0,0 GT:PL:DP ./.:0,0,0,0,.,0:0 ./.:0,0,0,0,.,0:0 diff --git a/test/norm.merge.vcf b/test/norm.merge.vcf new file mode 100644 index 0000000..c702f6d --- /dev/null +++ b/test/norm.merge.vcf @@ -0,0 +1,61 @@ +##fileformat=VCFv4.2 +##FILTER= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##contig= +##contig= +##contig= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##INFO= +##FILTER= +##FILTER= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT XY00001 XY00002 +1 105 . TAAACCCTAAA TAA 999 PASS INDEL;AN=4;AC=2;DP=19;ISTR=SomeString;XRF=1e+06,2e+06;XRI=1111,2222;XRS=AAA,BBB;XAF=1e+06;XAI=1111;XAS=AAA;XGF=1e+06,2e+06,3e+06;XGI=1111,2222,3333;XGS=A,B,C GT:PL:DP:FRF:FRI:FRS:FAF:FAI:FAS:FGF:FGI:FGS 1/0:1,2,3:1:1e+06,2e+06:1111,2222:AAAA,BBB:1e+06:1111:A:1e+06,2e+06,3e+06:1111,2222,3333:A,BB,CCC 1/0:1,2,3:1:1e+06,2e+06:1111,2222:AAAA,BBB:1e+06:1111:A:1e+06,2e+06,3e+06:1111,2222,3333:A,BB,CCC +1 105 . TAAACCCTAAA TAACCCTAAA 999 PASS INDEL;AN=4;AC=2;DP=19;ISTR=SomeString;XRF=1e+06,500000;XRI=1111,5555;XRS=AAA,DDD;XAF=500000;XAI=5555;XAS=DDD;XGF=1e+06,500000,9e+09;XGI=1111,5555,9999;XGS=A,E,F GT:PL:DP:FRF:FRI:FRS:FAF:FAI:FAS:FGF:FGI:FGS 0/1:1,4,6:1:1e+06,500000:1111,5555:AAAA,CC:500000:5555:BB:1e+06,500000,9e+09:1111,5555,9999:A,EEEE,FFFFF 0/1:1,4,6:1:1e+06,500000:1111,5555:AAAA,CC:500000:5555:BB:1e+06,500000,9e+09:1111,5555,9999:A,EEEE,FFFFF +2 1 . GGGCGTCTCATAGCTGGAGCAATGGCGAGCGCCTGGACAAGGGAGGGGAAGGGGTTCTTATTACTGACGCGGGTAGCCCCTACTGCTGTGTGGTTCCCCTATTTTTTTTTTTTTCTTTTTGAGACGGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGCACAATCTCGGCTCACTGCAAGCTCCACCT ACGT 999 PASS INDEL;AN=4;AC=2 GT:DP 1/0:1 1/0:1 +2 101 . ATTTTTTTTTTTTT ATTTTTTTTTTTTTTT 999 PASS INDEL;AN=4;AC=4 GT:DP 1/1:1 1/1:1 +2 114 . TC TTCC 999 FAIL1 INDEL;AN=4;AC=2 GT:DP:FGS 1/0:1:A,BB,CCC 1/0:1:AA,BB,CCC +2 114 . TC TTC 999 PASS INDEL;AN=4;AC=2 GT:DP:FGS 0/1:1:A,EEEE,FFFFF 0/1:1:AA,EEEE,FFFFF +2 115 . C T 999 PASS INDEL;AN=4;AC=4 GT:DP 1/1:1 1/1:1 +20 3 . G CT 999 PASS INDEL;AN=4;AC=2 GT 0/1 0/1 +20 3 . GATG GACT 999 PASS INDEL;AN=4;AC=2 GT 1/0 1/0 +20 5 . TGGG TAC . PASS INDEL;AN=4;AC=2 GT:PL:DP 1/0:1,2,3:1 1/0:1,2,3:1 +20 5 id0001 TGGG TG . PASS INDEL;AN=4;AC=2 GT:PL:DP 0/1:1,4,6:1 0/1:1,4,6:1 +20 5 id0002 TGGG TGGGG . PASS INDEL;AN=4;AC=0 GT:PL:DP 0/0:1,7,10:1 0/0:1,7,10:1 +20 5 . TGGG AC . PASS INDEL;AN=4;AC=0 GT:PL:DP 0/0:1,11,15:1 0/0:1,11,15:1 +20 59 id0003 AG . 999 PASS AN=4 GT:PL:DP 0/0:0:4 0/0:0:4 +20 80 . CACAG CACAT 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 +20 81 . A C 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 +20 95 . TCACCG ACACCG 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 +20 95 . TCACCG AAAAAA 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 +20 273 . CAAAAAAAAAAAAAAAAAAAAA CAAAAAAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=4;AC=2 GT:PL:DP 1/0:0,3,5:1 1/0:0,3,5:1 +20 273 . CAAAAAAAAAAAAAAAAAAAAA CAAAAAAAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=4;AC=2 GT:PL:DP 0/1:0,3,5:1 0/1:0,3,5:1 +20 274 . AAAAAAAAA AAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=0;AC=0 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 +20 275 . A C 0 FAIL1 INDEL;AN=2;AC=0 GT:PL:DP:FGF:FGI:FGS:FSTR 0:0,0:0:1e+06,2e+06:1111,2222:A,BB:WORD 0:0,0:0:1e+06,2e+06:1111,2222:A,BB:WORD +20 275 . A G 0 FAIL2 INDEL;AN=2;AC=2 GT:PL:DP:FGF:FGI:FGS:FSTR 1:0,0:0:1e+06,3e+06:1111,3333:A,CCC:WORD 1:0,0:0:1e+06,3e+06:1111,3333:A,CCC:WORD +20 278 . AAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=0;AC=0 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 +20 300 . A C 998 PASS INDEL;AN=0;AC=0 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 +20 300 . A G 999 PASS INDEL;AN=0;AC=0 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 diff --git a/test/norm.out b/test/norm.out new file mode 100644 index 0000000..002acdb --- /dev/null +++ b/test/norm.out @@ -0,0 +1,58 @@ +##fileformat=VCFv4.2 +##FILTER= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##contig= +##contig= +##contig= +##contig= +##contig= +##contig= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT XY00001 XY00002 +1 105 . TAAACCCTA T,TAACCCTA 999 PASS INDEL;AN=4;AC=2,2;DP=19;ISTR=SomeString;XRF=1e+06,2e+06,500000;XRI=1111,2222,5555;XRS=AAA,BBB,DDD;XAF=1e+06,500000;XAI=1111,5555;XAS=AAA,DDD;XGF=1e+06,2e+06,3e+06,500000,.,9e+09;XGI=1111,2222,3333,5555,.,9999;XGS=A,B,C,E,.,F GT:PL:DP:FRF:FRI:FRS:FAF:FAI:FAS:FGF:FGI:FGS 1/2:1,2,3,4,5,6:1:1e+06,2e+06,500000:1111,2222,5555:AAAA,BBB,CC:1e+06,500000:1111,5555:A,BB:1e+06,2e+06,3e+06,500000,.,9e+09:1111,2222,3333,5555,.,9999:A,BB,CCC,EEEE,.,FFFFF 1/2:1,2,3,4,5,6:1:1e+06,2e+06,500000:1111,2222,5555:AAAA,BBB,CC:1e+06,500000:1111,5555:A,BB:1e+06,2e+06,3e+06,500000,.,9e+09:1111,2222,3333,5555,.,9999:A,BB,CCC,EEEE,.,FFFFF +2 1 . GGGCGTCTCATAGCTGGAGCAATGGCGAGCGCCTGGACAAGGGAGGGGAAGGGGTTCTTATTACTGACGCGGGTAGCCCCTACTGCTGTGTGGTTCCCCTATTTTTTTTTTTTTCTTTTTGAGACGGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGCACAATCTCGGCTCACTGCAAGCTCCACC ACG 999 PASS INDEL;AN=4;AC=2 GT:DP 1/0:1 1/0:1 +2 101 . A ATT 999 PASS INDEL;AN=4;AC=4 GT:DP 1/1:1 1/1:1 +2 114 . T TTC,TT 999 PASS INDEL;AN=4;AC=2,2 GT:DP 1/2:1 1/2:1 +2 115 . C T 999 PASS INDEL;AN=4;AC=4 GT:DP 1/1:1 1/1:1 +20 3 . G CT 999 PASS INDEL;AN=4;AC=2 GT 0/1 0/1 +20 5 . TG CT 999 PASS INDEL;AN=4;AC=2 GT 1/0 1/0 +20 5 . TGGG TAC,TG,TGGGG,AC . PASS INDEL;AN=4;AC=2,2,0,0 GT:PL:DP 1/2:1,2,3,4,5,6,7,8,9,10,11,12,13,14,15:1 1/2:1,2,3,4,5,6,7,8,9,10,11,12,13,14,15:1 +20 59 . AG . 999 PASS AN=4 GT:PL:DP 0/0:0:4 0/0:0:4 +20 81 . A C 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 +20 84 . G T 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 +20 95 . T A 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 +20 95 . TCACCG AAAAAA 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 +20 273 . C CAA,CAAA 999 PASS INDEL;AN=4;AC=2,2 GT:PL:DP 1/2:0,3,5,3,5,5:1 1/2:0,3,5,3,5,5:1 +20 273 . C CAAAAAAAAAA 999 PASS INDEL;AN=0;AC=0 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 +20 273 . C CAA 999 PASS INDEL;AN=0;AC=0 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 +20 275 . A C,G 999 PASS INDEL;AN=2;AC=0,2 GT:PL:DP:FGF:FGI:FGS:FSTR 2:0,0,0:0:1e+06,2e+06,3e+06:1111,2222,3333:A,BB,CCC:WORD 2:0,0,0:0:1e+06,2e+06,3e+06:1111,2222,3333:A,BB,CCC:WORD +3 10 . GTGGAC GTGGACACAC,GTGGACAC,GTGGACACACAC,GTGG,GTGGACACACACAC,ATGGACACACAC 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 +3 17 . CA C 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 +4 25 . T TT,* 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 +4 36 . TC C,TT,TTC 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 +5 21 . A AAG 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 diff --git a/test/norm.setref.out b/test/norm.setref.out new file mode 100644 index 0000000..2856b0a --- /dev/null +++ b/test/norm.setref.out @@ -0,0 +1,45 @@ +##fileformat=VCFv4.2 +##FILTER= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##contig= +##contig= +##contig= +##contig= +##contig= +##contig= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT XY00001 XY00002 +1 105 . TAAACCCTAAA TAACCCTAAA,TAA 999 PASS INDEL;AN=4;AC=0,2;DP=19 GT 0/2 0/2 +2 101 . A c 999 PASS INDEL;AN=4;AC=4 GT:DP 1/1:1 1/1:1 +2 105 . T 999 PASS END=112;AN=4;AC=3 GT:DP 0/1:1 1/1:1 +2 115 . c t 999 PASS INDEL;AN=4;AC=0 GT:DP 0/0:1 0/0:1 +20 3 . g c 999 PASS INDEL;AN=4;AC=3 GT 1/1 1/0 +20 3 . gatg gact 999 PASS INDEL;AN=4;AC=2 GT 0/1 0/1 +20 10 . C . 999 PASS INDEL;AN=4;AC=1 GT 1/0 0/0 +20 275 . a c,g,t,aaa 999 PASS INDEL;AN=2;AC=0,0,0,0 GT 0 0 diff --git a/test/norm.setref.vcf b/test/norm.setref.vcf new file mode 100644 index 0000000..da78f10 --- /dev/null +++ b/test/norm.setref.vcf @@ -0,0 +1,45 @@ +##fileformat=VCFv4.2 +##FILTER= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##contig= +##contig= +##contig= +##contig= +##contig= +##contig= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT XY00001 XY00002 +1 105 . TAACCCTAAA TAAACCCTAAA,TAA 999 PASS INDEL;AN=4;AC=2,2;DP=19 GT 1/2 1/2 +2 101 . . c 999 PASS INDEL;AN=4;AC=4 GT:DP 1/1:1 1/1:1 +2 105 . n 999 PASS END=112;AN=4;AC=3 GT:DP 0/1:1 1/1:1 +2 115 . t c 999 PASS INDEL;AN=4;AC=4 GT:DP 1/1:1 1/1:1 +20 3 . c g 999 PASS INDEL;AN=4;AC=1 GT 0/0 0/1 +20 3 . gact gatg 999 PASS INDEL;AN=4;AC=2 GT 1/0 1/0 +20 10 . . . 999 PASS INDEL;AN=4;AC=1 GT 1/0 0/0 +20 275 . g c,a,t,aaa 999 PASS INDEL;AN=2;AC=0,2,0,0 GT 2 2 diff --git a/test/norm.split.2.out b/test/norm.split.2.out new file mode 100644 index 0000000..52fcecd --- /dev/null +++ b/test/norm.split.2.out @@ -0,0 +1,107 @@ +##fileformat=VCFv4.2 +##FILTER= +##samtoolsVersion=1.2-216-gdffc67f-dirty+htslib-1.2.1-216-gd2ed7e6-dirty +##reference=file:///usr/bio-ref/GRCh38.81/GRCh38.fa +##contig= +#CHROM POS ID REF ALT QUAL FILTER INFO +1 789241 . C G 41.4503 . . +1 789262 . G A 36.0809 . . +1 789280 . T C 40.0265 . . +1 789334 . A T 67 . . +1 789348 . T A 44.5622 . . +1 789368 . A T 18.5381 . . +1 789369 . C T 30.0396 . . +1 789396 . A C 35.7056 . . +1 789402 . G T 35.0554 . . +1 789403 . T A 35.0681 . . +1 789417 . T G 35.0681 . . +1 789420 . T A 35.0681 . . +1 789429 . A C 39.1119 . . +1 789435 . C T 35.1179 . . +1 789481 . G A 94 . . +1 789489 . C A 89 . . +1 789491 . C G 100 . . +1 789568 . TATGGAATGGAATGGAATGGAATG TATGGAATGGAATGGAATG 295 . . +1 789631 . G A 3.18972 . . +1 789642 . T G 3.66362 . . +1 789660 . C T 35.0294 . . +1 789666 . T G 16.1313 . . +1 789673 . A T 52 . . +1 789675 . T G 20.7408 . . +1 789676 . C T 26.6621 . . +1 789680 . A T 21.5713 . . +1 789680 . AGGAATGGAATGGAATGGAATGGAATGGAATGGAATGGAATGGACTCGAATGGAATGGAATGGAATG AGGAATGGAATGGAATGGAATGGAATGGAATGGAATGGAATGGAATGGAATGGACTCGAATGGAATGGAATGGAATG 23.495 . . +1 789685 . T G 6.53871 . . +1 789690 . T G 16.2287 . . +1 789690 . T C 16.2287 . . +1 789691 . G T 21.8633 . . +1 789691 . G C 21.8633 . . +1 789692 . G A 31.8203 . . +1 789695 . T A 7.03922 . . +1 789696 . G A 64 . . +1 789696 . G T 64 . . +1 789696 . G C 64 . . +1 789697 . G A 116 . . +1 789700 . T A 27.3447 . . +1 789700 . T G 27.3447 . . +1 789704 . A C 12.9378 . . +1 789704 . A T 12.9378 . . +1 789704 . A G 12.9378 . . +1 789706 . G C 4.49441 . . +1 789706 . G A 4.49441 . . +1 789707 . G C 6.28796 . . +1 789707 . G A 6.28796 . . +1 789710 . T G 59 . . +1 789710 . T A 59 . . +1 789711 . G T 15.1544 . . +1 789713 . A C 6.69714 . . +1 789717 . G A 82 . . +1 789720 . T G 26.241 . . +1 789721 . G A 99 . . +1 789721 . G T 99 . . +1 789727 . G A 5.18898 . . +1 789727 . G C 5.18898 . . +1 789730 . T A 73 . . +1 789730 . T C 73 . . +1 789731 . G T 111 . . +1 789732 . G T 24.8095 . . +1 789735 . T G 61 . . +1 789737 . G T 69 . . +1 789737 . G A 69 . . +1 789739 . A T 48.5355 . . +1 789740 . T A 29.8166 . . +1 789747 . A G 187 . . +1 789747 . A C 187 . . +1 789747 . A T 187 . . +1 789749 . C G 19.1565 . . +1 789750 . T A 12.5086 . . +1 789750 . T C 12.5086 . . +1 789752 . C G 284 . . +1 789757 . G A 7.13117 . . +1 789765 . T A 191 . . +1 789767 . G A 16.2222 . . +1 789769 . C T 17.4827 . . +1 789770 . T G 64 . . +1 789770 . T A 64 . . +1 789772 . G A 31.6793 . . +1 789772 . G C 31.6793 . . +1 789775 . T A 125 . . +1 789775 . T G 125 . . +1 789776 . A G 151 . . +1 789777 . G C 22.9639 . . +1 789781 . G A 89 . . +1 789795 . A T 11.555 . . +1 789816 . G A 29.3537 . . +1 789957 . C G 19.4796 . . +1 790009 . C T 55 . . +1 790136 . A G 85 . . +1 790156 . G A 19.4198 . . +1 790176 . A G 86 . . +1 790179 . C T 4.20807 . . +1 790181 . C T 12.5149 . . +1 790186 . G A 86 . . +1 790189 . T A 76 . . +1 790202 . G A 86 . . +1 790202 . G C 86 . . +1 790206 . C A 18.4041 . . +1 790206 . C T 18.4041 . . diff --git a/test/norm.split.2.vcf b/test/norm.split.2.vcf new file mode 100644 index 0000000..b8147fc --- /dev/null +++ b/test/norm.split.2.vcf @@ -0,0 +1,85 @@ +##fileformat=VCFv4.2 +##FILTER= +##samtoolsVersion=1.2-216-gdffc67f-dirty+htslib-1.2.1-216-gd2ed7e6-dirty +##reference=file:///usr/bio-ref/GRCh38.81/GRCh38.fa +##contig= +#CHROM POS ID REF ALT QUAL FILTER +1 789241 . C G 41.4503 . +1 789262 . G A 36.0809 . +1 789280 . T C 40.0265 . +1 789334 . A T 67 . +1 789348 . T A 44.5622 . +1 789368 . A T 18.5381 . +1 789369 . C T 30.0396 . +1 789396 . A C 35.7056 . +1 789402 . G T 35.0554 . +1 789403 . T A 35.0681 . +1 789417 . T G 35.0681 . +1 789420 . T A 35.0681 . +1 789429 . A C 39.1119 . +1 789435 . C T 35.1179 . +1 789481 . G A 94 . +1 789489 . C A 89 . +1 789491 . C G 100 . +1 789568 . TATGGAATGGAATGGAATGGAATG TATGGAATGGAATGGAATG 295 . +1 789631 . G A 3.18972 . +1 789642 . T G 3.66362 . +1 789660 . C T 35.0294 . +1 789666 . T G 16.1313 . +1 789673 . A T 52 . +1 789675 . T G 20.7408 . +1 789676 . C T 26.6621 . +1 789680 . A T 21.5713 . +1 789680 . AGGAATGGAATGGAATGGAATGGAATGGAATGGAATGGAATGGACTCGAATGGAATGGAATGGAATG AGGAATGGAATGGAATGGAATGGAATGGAATGGAATGGAATGGAATGGAATGGACTCGAATGGAATGGAATGGAATG 23.495 . +1 789685 . T G 6.53871 . +1 789690 . T G,C 16.2287 . +1 789691 . G T,C 21.8633 . +1 789692 . G A 31.8203 . +1 789695 . T A 7.03922 . +1 789696 . G A,T,C 64 . +1 789697 . G A 116 . +1 789700 . T A,G 27.3447 . +1 789704 . A C,T,G 12.9378 . +1 789706 . G C,A 4.49441 . +1 789707 . G C,A 6.28796 . +1 789710 . T G,A 59 . +1 789711 . G T 15.1544 . +1 789713 . A C 6.69714 . +1 789717 . G A 82 . +1 789720 . T G 26.241 . +1 789721 . G A,T 99 . +1 789727 . G A,C 5.18898 . +1 789730 . T A,C 73 . +1 789731 . G T 111 . +1 789732 . G T 24.8095 . +1 789735 . T G 61 . +1 789737 . G T,A 69 . +1 789739 . A T 48.5355 . +1 789740 . T A 29.8166 . +1 789747 . A G,C,T 187 . +1 789749 . C G 19.1565 . +1 789750 . T A,C 12.5086 . +1 789752 . C G 284 . +1 789757 . G A 7.13117 . +1 789765 . T A 191 . +1 789767 . G A 16.2222 . +1 789769 . C T 17.4827 . +1 789770 . T G,A 64 . +1 789772 . G A,C 31.6793 . +1 789775 . T A,G 125 . +1 789776 . A G 151 . +1 789777 . G C 22.9639 . +1 789781 . G A 89 . +1 789795 . A T 11.555 . +1 789816 . G A 29.3537 . +1 789957 . C G 19.4796 . +1 790009 . C T 55 . +1 790136 . A G 85 . +1 790156 . G A 19.4198 . +1 790176 . A G 86 . +1 790179 . C T 4.20807 . +1 790181 . C T 12.5149 . +1 790186 . G A 86 . +1 790189 . T A 76 . +1 790202 . G A,C 86 . +1 790206 . C A,T 18.4041 . \ No newline at end of file diff --git a/test/norm.split.and.norm.out b/test/norm.split.and.norm.out new file mode 100644 index 0000000..64838ed --- /dev/null +++ b/test/norm.split.and.norm.out @@ -0,0 +1,64 @@ +##fileformat=VCFv4.2 +##FILTER= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##contig= +##contig= +##contig= +##contig= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT XY00001 XY00002 +1 105 . TAAACCCTA T 999 PASS INDEL;AN=4;AC=2;DP=19;ISTR=SomeString;XRF=1e+06,2e+06;XRI=1111,2222;XRS=AAA,BBB;XAF=1e+06;XAI=1111;XAS=AAA;XGF=1e+06,2e+06,3e+06;XGI=1111,2222,3333;XGS=A,B,C GT:PL:DP:FRF:FRI:FRS:FAF:FAI:FAS:FGF:FGI:FGS 1/0:1,2,3:1:1e+06,2e+06:1111,2222:AAAA,BBB:1e+06:1111:A:1e+06,2e+06,3e+06:1111,2222,3333:A,BB,CCC 1/0:1,2,3:1:1e+06,2e+06:1111,2222:AAAA,BBB:1e+06:1111:A:1e+06,2e+06,3e+06:1111,2222,3333:A,BB,CCC +1 105 . TA T 999 PASS INDEL;AN=4;AC=2;DP=19;ISTR=SomeString;XRF=1e+06,500000;XRI=1111,5555;XRS=AAA,DDD;XAF=500000;XAI=5555;XAS=DDD;XGF=1e+06,500000,9e+09;XGI=1111,5555,9999;XGS=A,E,F GT:PL:DP:FRF:FRI:FRS:FAF:FAI:FAS:FGF:FGI:FGS 0/1:1,4,6:1:1e+06,500000:1111,5555:AAAA,CC:500000:5555:BB:1e+06,500000,9e+09:1111,5555,9999:A,EEEE,FFFFF 0/1:1,4,6:1:1e+06,500000:1111,5555:AAAA,CC:500000:5555:BB:1e+06,500000,9e+09:1111,5555,9999:A,EEEE,FFFFF +2 1 . GGGCGTCTCATAGCTGGAGCAATGGCGAGCGCCTGGACAAGGGAGGGGAAGGGGTTCTTATTACTGACGCGGGTAGCCCCTACTGCTGTGTGGTTCCCCTATTTTTTTTTTTTTCTTTTTGAGACGGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGCACAATCTCGGCTCACTGCAAGCTCCACC ACG 999 PASS INDEL;AN=4;AC=2 GT:DP 1/0:1 1/0:1 +2 101 . A ATT 999 PASS INDEL;AN=4;AC=4 GT:DP 1/1:1 1/1:1 +2 101 . A AT 999 PASS INDEL;AN=4;AC=2 GT:DP 0/1:1 0/1:1 +2 114 . T TTC 999 PASS INDEL;AN=4;AC=2 GT:DP 1/0:1 1/0:1 +2 115 . C T 999 PASS INDEL;AN=4;AC=4 GT:DP 1/1:1 1/1:1 +20 3 . G CT 999 PASS INDEL;AN=4;AC=2 GT 0/1 0/1 +20 5 . TG CT 999 PASS INDEL;AN=4;AC=2 GT 1/0 1/0 +20 5 . TGG T . PASS INDEL;AN=4;AC=2 GT:PL:DP 0/1:1,4,6:1 0/1:1,4,6:1 +20 5 . T TG . PASS INDEL;AN=4;AC=0 GT:PL:DP 0/0:1,7,10:1 0/0:1,7,10:1 +20 5 . TGGG AC . PASS INDEL;AN=4;AC=0 GT:PL:DP 0/0:1,11,15:1 0/0:1,11,15:1 +20 6 . GGG AC . PASS INDEL;AN=4;AC=2 GT:PL:DP 1/0:1,2,3:1 1/0:1,2,3:1 +20 59 . AG . 999 PASS AN=4 GT:PL:DP 0/0:0:4 0/0:0:4 +20 81 . A C 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 +20 84 . G T 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 +20 95 . T A 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 +20 95 . TCACCG AAAAAA 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 +20 273 . C CAA 999 PASS INDEL;AN=4;AC=2 GT:PL:DP 1/0:0,3,5:1 1/0:0,3,5:1 +20 273 . C CAAA 999 PASS INDEL;AN=4;AC=2 GT:PL:DP 0/1:0,3,5:1 0/1:0,3,5:1 +20 273 . C CAAAAAAAAAA 999 PASS INDEL;AN=0;AC=0 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 +20 273 . C CAA 999 PASS INDEL;AN=0;AC=0 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 +20 275 . A C 999 PASS INDEL;AN=2;AC=0 GT:PL:DP:FGF:FGI:FGS:FSTR 0:0,0:0:1e+06,2e+06:1111,2222:A,BB:WORD 0:0,0:0:1e+06,2e+06:1111,2222:A,BB:WORD +20 275 . A G 999 PASS INDEL;AN=2;AC=2 GT:PL:DP:FGF:FGI:FGS:FSTR 1:0,0:0:1e+06,3e+06:1111,3333:A,CCC:WORD 1:0,0:0:1e+06,3e+06:1111,3333:A,CCC:WORD +20 300 . T C 999 PASS INDEL;AN=0;AC=0 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 +20 300 . T G 999 PASS INDEL;AN=0;AC=0 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 +21 1 id T TTTATTA 999 PASS INDEL;AN=0;AC=0 GT:DP ./.:0 ./.:0 +21 1 id T TTTATTATTATTATTATTA 999 PASS INDEL;AN=0;AC=0 GT:DP ./.:0 ./.:0 +21 1 id TTTA T 999 PASS INDEL;AN=0;AC=0 GT:DP ./.:0 ./.:0 +21 1 id T TTATTA 999 PASS INDEL;AN=0;AC=0 GT:DP ./.:0 ./.:0 diff --git a/test/norm.split.out b/test/norm.split.out new file mode 100644 index 0000000..b919211 --- /dev/null +++ b/test/norm.split.out @@ -0,0 +1,64 @@ +##fileformat=VCFv4.2 +##FILTER= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##contig= +##contig= +##contig= +##contig= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT XY00001 XY00002 +1 105 . TAAACCCTAAA TAA 999 PASS INDEL;AN=4;AC=2;DP=19;ISTR=SomeString;XRF=1e+06,2e+06;XRI=1111,2222;XRS=AAA,BBB;XAF=1e+06;XAI=1111;XAS=AAA;XGF=1e+06,2e+06,3e+06;XGI=1111,2222,3333;XGS=A,B,C GT:PL:DP:FRF:FRI:FRS:FAF:FAI:FAS:FGF:FGI:FGS 1/0:1,2,3:1:1e+06,2e+06:1111,2222:AAAA,BBB:1e+06:1111:A:1e+06,2e+06,3e+06:1111,2222,3333:A,BB,CCC 1/0:1,2,3:1:1e+06,2e+06:1111,2222:AAAA,BBB:1e+06:1111:A:1e+06,2e+06,3e+06:1111,2222,3333:A,BB,CCC +1 105 . TAAACCCTAAA TAACCCTAAA 999 PASS INDEL;AN=4;AC=2;DP=19;ISTR=SomeString;XRF=1e+06,500000;XRI=1111,5555;XRS=AAA,DDD;XAF=500000;XAI=5555;XAS=DDD;XGF=1e+06,500000,9e+09;XGI=1111,5555,9999;XGS=A,E,F GT:PL:DP:FRF:FRI:FRS:FAF:FAI:FAS:FGF:FGI:FGS 0/1:1,4,6:1:1e+06,500000:1111,5555:AAAA,CC:500000:5555:BB:1e+06,500000,9e+09:1111,5555,9999:A,EEEE,FFFFF 0/1:1,4,6:1:1e+06,500000:1111,5555:AAAA,CC:500000:5555:BB:1e+06,500000,9e+09:1111,5555,9999:A,EEEE,FFFFF +2 1 . GGGCGTCTCATAGCTGGAGCAATGGCGAGCGCCTGGACAAGGGAGGGGAAGGGGTTCTTATTACTGACGCGGGTAGCCCCTACTGCTGTGTGGTTCCCCTATTTTTTTTTTTTTCTTTTTGAGACGGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGCACAATCTCGGCTCACTGCAAGCTCCACCT ACGT 999 PASS INDEL;AN=4;AC=2 GT:DP 1/0:1 1/0:1 +2 101 . ATTTTTTTTTTTTT ATTTTTTTTTTTTTTT 999 PASS INDEL;AN=4;AC=4 GT:DP 1/1:1 1/1:1 +2 114 . TC TTCC 999 PASS INDEL;AN=4;AC=2 GT:DP 1/0:1 1/0:1 +2 114 . TC TTC 999 PASS INDEL;AN=4;AC=2 GT:DP 0/1:1 0/1:1 +2 115 . C T 999 PASS INDEL;AN=4;AC=4 GT:DP 1/1:1 1/1:1 +20 3 . G CT 999 PASS INDEL;AN=4;AC=2 GT 0/1 0/1 +20 3 . GATG GACT 999 PASS INDEL;AN=4;AC=2 GT 1/0 1/0 +20 5 . TGGG TAC . PASS INDEL;AN=4;AC=2 GT:PL:DP 1/0:1,2,3:1 1/0:1,2,3:1 +20 5 . TGGG TG . PASS INDEL;AN=4;AC=2 GT:PL:DP 0/1:1,4,6:1 0/1:1,4,6:1 +20 5 . TGGG TGGGG . PASS INDEL;AN=4;AC=0 GT:PL:DP 0/0:1,7,10:1 0/0:1,7,10:1 +20 5 . TGGG AC . PASS INDEL;AN=4;AC=0 GT:PL:DP 0/0:1,11,15:1 0/0:1,11,15:1 +20 59 . AG . 999 PASS AN=4 GT:PL:DP 0/0:0:4 0/0:0:4 +20 80 . CACAG CACAT 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 +20 81 . A C 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 +20 95 . TCACCG ACACCG 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 +20 95 . TCACCG AAAAAA 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 +20 273 . CAAAAAAAAAAAAAAAAAAAAA CAAAAAAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=4;AC=2 GT:PL:DP 1/0:0,3,5:1 1/0:0,3,5:1 +20 273 . CAAAAAAAAAAAAAAAAAAAAA CAAAAAAAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=4;AC=2 GT:PL:DP 0/1:0,3,5:1 0/1:0,3,5:1 +20 274 . AAAAAAAAA AAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=0;AC=0 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 +20 275 . A C 999 PASS INDEL;AN=2;AC=0 GT:PL:DP:FGF:FGI:FGS:FSTR 0:0,0:0:1e+06,2e+06:1111,2222:A,BB:WORD 0:0,0:0:1e+06,2e+06:1111,2222:A,BB:WORD +20 275 . A G 999 PASS INDEL;AN=2;AC=2 GT:PL:DP:FGF:FGI:FGS:FSTR 1:0,0:0:1e+06,3e+06:1111,3333:A,CCC:WORD 1:0,0:0:1e+06,3e+06:1111,3333:A,CCC:WORD +20 278 . AAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=0;AC=0 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 +20 300 . T C 999 PASS INDEL;AN=0;AC=0 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 +20 300 . T G 999 PASS INDEL;AN=0;AC=0 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 +21 1 id TTTA TTTATTATTA 999 PASS INDEL;AN=0;AC=0 GT:DP ./.:0 ./.:0 +21 1 id TTTA TTTATTATTATTATTATTATTA 999 PASS INDEL;AN=0;AC=0 GT:DP ./.:0 ./.:0 +21 1 id TTTA T 999 PASS INDEL;AN=0;AC=0 GT:DP ./.:0 ./.:0 +21 1 id TTTA TTATTATTA 999 PASS INDEL;AN=0;AC=0 GT:DP ./.:0 ./.:0 diff --git a/test/norm.split.vcf b/test/norm.split.vcf new file mode 100644 index 0000000..7f039d1 --- /dev/null +++ b/test/norm.split.vcf @@ -0,0 +1,53 @@ +##fileformat=VCFv4.2 +##FILTER= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##contig= +##contig= +##contig= +##contig= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT XY00001 XY00002 +1 105 . TAAACCCTAAA TAA,TAACCCTAAA 999 PASS INDEL;AN=4;AC=2,2;DP=19;ISTR=SomeString;XRF=1e+06,2e+06,500000;XRI=1111,2222,5555;XRS=AAA,BBB,DDD;XAF=1e+06,500000;XAI=1111,5555;XAS=AAA,DDD;XGF=1e+06,2e+06,3e+06,500000,.,9e+09;XGI=1111,2222,3333,5555,.,9999;XGS=A,B,C,E,.,F GT:PL:DP:FRF:FRI:FRS:FAF:FAI:FAS:FGF:FGI:FGS 1/2:1,2,3,4,5,6:1:1e+06,2e+06,500000:1111,2222,5555:AAAA,BBB,CC:1e+06,500000:1111,5555:A,BB:1e+06,2e+06,3e+06,500000,.,9e+09:1111,2222,3333,5555,.,9999:A,BB,CCC,EEEE,.,FFFFF 1/2:1,2,3,4,5,6:1:1e+06,2e+06,500000:1111,2222,5555:AAAA,BBB,CC:1e+06,500000:1111,5555:A,BB:1e+06,2e+06,3e+06,500000,.,9e+09:1111,2222,3333,5555,.,9999:A,BB,CCC,EEEE,.,FFFFF +2 1 . GGGCGTCTCATAGCTGGAGCAATGGCGAGCGCCTGGACAAGGGAGGGGAAGGGGTTCTTATTACTGACGCGGGTAGCCCCTACTGCTGTGTGGTTCCCCTATTTTTTTTTTTTTCTTTTTGAGACGGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGCACAATCTCGGCTCACTGCAAGCTCCACCT ACGT 999 PASS INDEL;AN=4;AC=2 GT:DP 1/0:1 1/0:1 +2 101 . ATTTTTTTTTTTTT ATTTTTTTTTTTTTTT 999 PASS INDEL;AN=4;AC=4 GT:DP 1/1:1 1/1:1 +2 114 . TC TTCC,TTC 999 PASS INDEL;AN=4;AC=2,2 GT:DP 1/2:1 1/2:1 +2 115 . C T 999 PASS INDEL;AN=4;AC=4 GT:DP 1/1:1 1/1:1 +20 3 . G CT 999 PASS INDEL;AN=4;AC=2 GT 0/1 0/1 +20 3 . GATG GACT 999 PASS INDEL;AN=4;AC=2 GT 1/0 1/0 +20 5 . TGGG TAC,TG,TGGGG,AC . PASS INDEL;AN=4;AC=2,2,0,0 GT:PL:DP 1/2:1,2,3,4,5,6,7,8,9,10,11,12,13,14,15:1 1/2:1,2,3,4,5,6,7,8,9,10,11,12,13,14,15:1 +20 59 . AG . 999 PASS AN=4 GT:PL:DP 0/0:0:4 0/0:0:4 +20 80 . CACAG CACAT 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 +20 81 . A C 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 +20 95 . TCACCG ACACCG 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 +20 95 . TCACCG AAAAAA 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 +20 273 . CAAAAAAAAAAAAAAAAAAAAA CAAAAAAAAAAAAAAAAAAAAAAA,CAAAAAAAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=4;AC=2,2 GT:PL:DP 1/2:0,3,5,3,5,5:1 1/2:0,3,5,3,5,5:1 +20 274 . AAAAAAAAA AAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=0;AC=0 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 +20 275 . A C,G 999 PASS INDEL;AN=2;AC=0,2 GT:PL:DP:FGF:FGI:FGS:FSTR 2:0,0,0:0:1e+06,2e+06,3e+06:1111,2222,3333:A,BB,CCC:WORD 2:0,0,0:0:1e+06,2e+06,3e+06:1111,2222,3333:A,BB,CCC:WORD +20 278 . AAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=0;AC=0 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 +20 300 . T C,G 999 PASS INDEL;AN=0;AC=0,0 GT:PL:DP ./.:0,0,0,0,0,0:0 ./.:0,0,0,0,0,0:0 +21 1 id TTTA TTTATTATTA,TTTATTATTATTATTATTATTA,T,TTATTATTA 999 PASS INDEL;AN=0;AC=0,0,0,0 GT:DP ./.:0 ./.:0 diff --git a/test/norm.telomere.out b/test/norm.telomere.out new file mode 100644 index 0000000..59431fa --- /dev/null +++ b/test/norm.telomere.out @@ -0,0 +1,5 @@ +##fileformat=VCFv4.2 +##FILTER= +##contig= +#CHROM POS ID REF ALT QUAL FILTER INFO +22 1 . NN N . . . diff --git a/test/norm.telomere.vcf b/test/norm.telomere.vcf new file mode 100644 index 0000000..55ff94b --- /dev/null +++ b/test/norm.telomere.vcf @@ -0,0 +1,4 @@ +##fileformat=VCFv4.2 +##contig= +#CHROM POS ID REF ALT QUAL FILTER INFO +22 17 . NN N . . . diff --git a/test/norm.vcf b/test/norm.vcf new file mode 100644 index 0000000..d7d7841 --- /dev/null +++ b/test/norm.vcf @@ -0,0 +1,59 @@ +##fileformat=VCFv4.2 +##FILTER= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##contig= +##contig= +##contig= +##contig= +##contig= +##contig= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT XY00001 XY00002 +1 105 . TAAACCCTAAA TAA,TAACCCTAAA 999 PASS INDEL;AN=4;AC=2,2;DP=19;ISTR=SomeString;XRF=1e+06,2e+06,500000;XRI=1111,2222,5555;XRS=AAA,BBB,DDD;XAF=1e+06,500000;XAI=1111,5555;XAS=AAA,DDD;XGF=1e+06,2e+06,3e+06,500000,.,9e+09;XGI=1111,2222,3333,5555,.,9999;XGS=A,B,C,E,.,F GT:PL:DP:FRF:FRI:FRS:FAF:FAI:FAS:FGF:FGI:FGS 1/2:1,2,3,4,5,6:1:1e+06,2e+06,500000:1111,2222,5555:AAAA,BBB,CC:1e+06,500000:1111,5555:A,BB:1e+06,2e+06,3e+06,500000,.,9e+09:1111,2222,3333,5555,.,9999:A,BB,CCC,EEEE,.,FFFFF 1/2:1,2,3,4,5,6:1:1e+06,2e+06,500000:1111,2222,5555:AAAA,BBB,CC:1e+06,500000:1111,5555:A,BB:1e+06,2e+06,3e+06,500000,.,9e+09:1111,2222,3333,5555,.,9999:A,BB,CCC,EEEE,.,FFFFF +2 1 . GGGCGTCTCATAGCTGGAGCAATGGCGAGCGCCTGGACAAGGGAGGGGAAGGGGTTCTTATTACTGACGCGGGTAGCCCCTACTGCTGTGTGGTTCCCCTATTTTTTTTTTTTTCTTTTTGAGACGGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGCACAATCTCGGCTCACTGCAAGCTCCACCT ACGT 999 PASS INDEL;AN=4;AC=2 GT:DP 1/0:1 1/0:1 +2 101 . ATTTTTTTTTTTTT ATTTTTTTTTTTTTTT 999 PASS INDEL;AN=4;AC=4 GT:DP 1/1:1 1/1:1 +2 114 . TC TTCC,TTC 999 PASS INDEL;AN=4;AC=2,2 GT:DP 1/2:1 1/2:1 +2 115 . C T 999 PASS INDEL;AN=4;AC=4 GT:DP 1/1:1 1/1:1 +20 3 . G CT 999 PASS INDEL;AN=4;AC=2 GT 0/1 0/1 +20 3 . GATG GACT 999 PASS INDEL;AN=4;AC=2 GT 1/0 1/0 +20 5 . TGGG TAC,TG,TGGGG,AC . PASS INDEL;AN=4;AC=2,2,0,0 GT:PL:DP 1/2:1,2,3,4,5,6,7,8,9,10,11,12,13,14,15:1 1/2:1,2,3,4,5,6,7,8,9,10,11,12,13,14,15:1 +20 59 . AG . 999 PASS AN=4 GT:PL:DP 0/0:0:4 0/0:0:4 +20 80 . CACAG CACAT 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 +20 81 . A C 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 +20 95 . TCACCG ACACCG 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 +20 95 . TCACCG AAAAAA 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 +20 273 . CAAAAAAAAAAAAAAAAAAAAA CAAAAAAAAAAAAAAAAAAAAAAA,CAAAAAAAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=4;AC=2,2 GT:PL:DP 1/2:0,3,5,3,5,5:1 1/2:0,3,5,3,5,5:1 +20 274 . AAAAAAAAA AAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=0;AC=0 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 +20 275 . A C,G 999 PASS INDEL;AN=2;AC=0,2 GT:PL:DP:FGF:FGI:FGS:FSTR 2:0,0,0:0:1e+06,2e+06,3e+06:1111,2222,3333:A,BB,CCC:WORD 2:0,0,0:0:1e+06,2e+06,3e+06:1111,2222,3333:A,BB,CCC:WORD +20 278 . AAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=0;AC=0 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 +3 10 . GTGGAC GTGGACACAC,GTGGACAC,GTGGACACACAC,GTGG,GTGGACACACACAC,ATGGACACACAC 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 +3 15 . CACA CAC 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 +4 21 . ATTTTTTTTTTTTTTTC ATTTTTTTTTTTTTTC,ATTTTTTTTTTTTTTTT,ATTTTTTTTTTTTTTTTC 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 +4 25 . T TT,* 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 +4 37 . C I 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 +5 22 . A AGA 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 diff --git a/test/plugin-missing2ref.out.vcf b/test/plugin-missing2ref.out.vcf new file mode 100644 index 0000000..2e8d1b9 --- /dev/null +++ b/test/plugin-missing2ref.out.vcf @@ -0,0 +1,30 @@ +##fileformat=VCFv4.1 +##FILTER= +##INFO= +##FORMAT= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FILTER= +##FILTER= +##contig= +##contig= +##contig= +##contig= +##test= +##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta +##readme=AAAAAA +##readme=BBBBBB +##INFO= +##INFO= +##bcftools_pluginCommand=plugin missing2ref -o test.out.vcf -- missing2ref -p -m +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B C D +1 3000150 . C T 59.2 PASS . GT:GQ 1|1:245 1|1:245 0/1:245 1/1:245 +1 3000151 . C T 59.2 PASS . GT:DP:GQ 0|0:32:245 0|0:32:245 0|0:32:245 0|0:32:245 +1 3062915 id3D GTTT G 12.9 q10 DP4=1,2,3,4;INDEL;STR=test GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 0/1:409:35:-20,-5,-20 0/1:409:35:-20,-5,-20 0/1:409:35:-20,-5,-20 +1 3062915 idSNP G T,C 12.6 test TEST=5;DP4=1,2,3,4 GT:TT:GQ:DP:GL 0/1:0,1:409:35:-20,-5,-20,-20,-5,-20 2:0,1:409:35:-20,-5,-20 2/2:0,1:409:35:-20,-5,-20 2|2:0,1:409:35:-20,-5,-20 +2 3199812 . G GTT,GT 82.7 PASS . GT:GQ:DP 0|0:322:26 0|0:322:26 0|0:322:26 0|0:322:26 +3 3212016 . CTT C,CT 79 PASS . GT:GQ:DP 0|0:91:26 0|0:91:26 0|0:91:26 0|0:91:26 +4 3258448 . TACACACAC T 59.9 PASS . GT:GQ:DP 0|0:325:31 0|0:325:31 0|0:325:31 0|0:325:31 diff --git a/test/plugin-missing2ref.vcf b/test/plugin-missing2ref.vcf new file mode 100644 index 0000000..2fe8c0a --- /dev/null +++ b/test/plugin-missing2ref.vcf @@ -0,0 +1,29 @@ +##fileformat=VCFv4.1 +##FILTER= +##INFO= +##FORMAT= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FILTER= +##FILTER= +##contig= +##contig= +##contig= +##contig= +##test= +##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta +##readme=AAAAAA +##readme=BBBBBB +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B C D +1 3000150 . C T 59.2 PASS . GT:GQ ./.:245 ./.:245 0/1:245 1/1:245 +1 3000151 . C T 59.2 PASS . GT:DP:GQ ./.:32:245 ./.:32:245 0|0:32:245 0|0:32:245 +1 3062915 id3D GTTT G 12.9 q10 DP4=1,2,3,4;INDEL;STR=test GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 0/1:409:35:-20,-5,-20 0/1:409:35:-20,-5,-20 0/1:409:35:-20,-5,-20 +1 3062915 idSNP G T,C 12.6 test TEST=5;DP4=1,2,3,4 GT:TT:GQ:DP:GL 0/1:0,1:409:35:-20,-5,-20,-20,-5,-20 2:0,1:409:35:-20,-5,-20 2/2:0,1:409:35:-20,-5,-20 ./.:0,1:409:35:-20,-5,-20 +2 3199812 . G GTT,GT 82.7 PASS . GT:GQ:DP ./.:322:26 ./.:322:26 ./.:322:26 ./.:322:26 +3 3212016 . CTT C,CT 79 PASS . GT:GQ:DP ./.:91:26 ./.:91:26 ./.:91:26 ./.:91:26 +4 3258448 . TACACACAC T 59.9 PASS . GT:GQ:DP ./.:325:31 ./.:325:31 ./.:325:31 ./.:325:31 diff --git a/test/plugin1.vcf b/test/plugin1.vcf new file mode 100644 index 0000000..e639868 --- /dev/null +++ b/test/plugin1.vcf @@ -0,0 +1,36 @@ +##fileformat=VCFv4.1 +##FILTER= +##INFO= +##FORMAT= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FILTER= +##FILTER= +##contig= +##contig= +##contig= +##contig= +##test= +##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta +##readme=AAAAAA +##readme=BBBBBB +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B +1 3000150 . C T 59.2 PASS . GT:GQ ./.:245 ./.:245 +1 3000151 . C T 59.2 PASS . GT:DP:GQ ./.:32:245 ./.:32:245 +1 3062915 id3D GTTT G 12.9 q10 DP4=1,2,3,4;INDEL;STR=test GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 0/1:409:35:-20,-5,-20 +1 3062915 idSNP G T,C 12.6 test TEST=5;DP4=1,2,3,4 GT:TT:GQ:DP:GL 0/1:0,1:409:35:-20,-5,-20,-20,-5,-20 2:0,1:409:35:-20,-5,-20 +1 3106154 . CAAA C 342 PASS . GT:GQ:DP ./.:245:32 ./.:245:32 +1 3106154 . C CT 59.2 PASS . GT:GQ:DP ./.:245:32 ./.:245:32 +1 3157410 . GA G 90.6 q10 . GT:GQ:DP 1/1:21:21 1/1:21:21 +1 3162006 . GAA G 60.2 PASS . GT:GQ:DP ./.:212:22 ./.:212:22 +1 3177144 . G T 45 PASS . GT:GQ:DP ./.:150:30 ./.:150:30 +1 3177144 . G . 45 PASS . GT:GQ:DP ./.:150:30 ./.:150:30 +1 3184885 . TAAAA TA,T 61.5 PASS . GT:GQ:DP ./.:12:10 ./.:12:10 +2 3199812 . G GTT,GT 82.7 PASS . GT:GQ:DP ./.:322:26 ./.:322:26 +3 3212016 . CTT C,CT 79 PASS . GT:GQ:DP ./.:91:26 ./.:91:26 +4 3258448 . TACACACAC T 59.9 PASS . GT:GQ:DP ./.:325:31 ./.:325:31 diff --git a/test/query.10.out b/test/query.10.out new file mode 100644 index 0000000..fb8c4e4 --- /dev/null +++ b/test/query.10.out @@ -0,0 +1 @@ +3258449 1/1 0/1 diff --git a/test/query.11.out b/test/query.11.out new file mode 100644 index 0000000..d9a859d --- /dev/null +++ b/test/query.11.out @@ -0,0 +1,2 @@ +3062915 0/1 0/2 +3258449 1/1 0/1 diff --git a/test/query.12.out b/test/query.12.out new file mode 100644 index 0000000..d1292d9 --- /dev/null +++ b/test/query.12.out @@ -0,0 +1,5 @@ +I8=. I16=. I32=. IF=. IA8=. IA16=. IA32=. IAF=. IA8=. IA16=. IA32=. IAF=. .:.:.:. .:.:.:. +I8=. I16=. I32=. IF=. IA8=. IA16=. IA32=. IAF=. IA8=. IA16=. IA32=. IAF=. .:.:.:. .:.:.:. +I8=. I16=. I32=. IF=. IA8=10,. IA16=1000,. IA32=100000,. IAF=0.003,. IA8=. IA16=. IA32=. IAF=. 10:1000:100000:0.003 .:.:.:. +I8=. I16=. I32=. IF=. IA8=. IA16=. IA32=. IAF=. IA8=. IA16=. IA32=. IAF=. 10:1000:100000:0.003 .:.:.:. +I8=. I16=. I32=. IF=. IA8=. IA16=. IA32=. IAF=. IA8=. IA16=. IA32=. IAF=. 10:1000:100000:0.003 .:.:.:. diff --git a/test/query.13.out b/test/query.13.out new file mode 100644 index 0000000..c2651d4 --- /dev/null +++ b/test/query.13.out @@ -0,0 +1,3 @@ +3000151 1 0 +3000152 0 1 +3000153 1 1 diff --git a/test/query.14.out b/test/query.14.out new file mode 100644 index 0000000..a3b53bc --- /dev/null +++ b/test/query.14.out @@ -0,0 +1,3 @@ +3000150 0 0 +3000151 1 0 +3000152 0 1 diff --git a/test/query.15.out b/test/query.15.out new file mode 100644 index 0000000..b601ad9 --- /dev/null +++ b/test/query.15.out @@ -0,0 +1 @@ +3000150 0 0 diff --git a/test/query.16.out b/test/query.16.out new file mode 100644 index 0000000..2e18f68 --- /dev/null +++ b/test/query.16.out @@ -0,0 +1 @@ +3000153 1 1 diff --git a/test/query.17.out b/test/query.17.out new file mode 100644 index 0000000..93a4845 --- /dev/null +++ b/test/query.17.out @@ -0,0 +1 @@ +1 2 3 4 diff --git a/test/query.18.out b/test/query.18.out new file mode 100644 index 0000000..9618498 --- /dev/null +++ b/test/query.18.out @@ -0,0 +1,2 @@ +3000002 . +3000003 . diff --git a/test/query.19.out b/test/query.19.out new file mode 100644 index 0000000..f16b4ab --- /dev/null +++ b/test/query.19.out @@ -0,0 +1,3 @@ +3000001 11 +3000004 11 +3000005 1 diff --git a/test/query.2.out b/test/query.2.out new file mode 100644 index 0000000..904574b --- /dev/null +++ b/test/query.2.out @@ -0,0 +1 @@ +1111,2222,3333 diff --git a/test/query.2.vcf b/test/query.2.vcf new file mode 100644 index 0000000..dbcd97c --- /dev/null +++ b/test/query.2.vcf @@ -0,0 +1,11 @@ +##fileformat=VCFv4.1 +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##FORMAT= +##contig= +##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT C D +1 3062915 . GTTT G 48.7 . XX_A=1;XX.A=2;XX.A0=3;xx.a0=4 GT 0/1 0/1 diff --git a/test/query.20.out b/test/query.20.out new file mode 100644 index 0000000..9618498 --- /dev/null +++ b/test/query.20.out @@ -0,0 +1,2 @@ +3000002 . +3000003 . diff --git a/test/query.21.out b/test/query.21.out new file mode 100644 index 0000000..ead31a1 --- /dev/null +++ b/test/query.21.out @@ -0,0 +1,3 @@ +3000001 1.1 +3000004 1.1 +3000005 1 diff --git a/test/query.22.out b/test/query.22.out new file mode 100644 index 0000000..9618498 --- /dev/null +++ b/test/query.22.out @@ -0,0 +1,2 @@ +3000002 . +3000003 . diff --git a/test/query.23.out b/test/query.23.out new file mode 100644 index 0000000..3594a84 --- /dev/null +++ b/test/query.23.out @@ -0,0 +1,3 @@ +3000001 xxx +3000004 xxx +3000005 .. diff --git a/test/query.24.out b/test/query.24.out new file mode 100644 index 0000000..0fb1c83 --- /dev/null +++ b/test/query.24.out @@ -0,0 +1,3 @@ +3000003 . +3000004 xxx +3000005 .. diff --git a/test/query.25.out b/test/query.25.out new file mode 100644 index 0000000..24af0d0 --- /dev/null +++ b/test/query.25.out @@ -0,0 +1,13 @@ +1 3062915 id3D GTTT G 48.7 q10 DP4=1,2,3,4;AN=4;AC=2 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 0/1:109:25:-10,-5,-20 +1 3062915 idSNP G C,T 419 test TEST=5;DP4=1,2,3,4;AN=4;AC=1,1 GT:TT:GQ:DP:GL 0/1:0,1:409:35:-20,-5,-20,-20,-5,-20 0/2:0,1:109:35:-10,-5,-20,-20,-5,-20 +1 3062915 id2D GTT G 999 q10 DP4=1,2,3,4;AN=4;AC=2 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 0/1:109:25:-10,-5,-20 +1 3106154 . CAAA C 72.6 PASS AN=0;AC=0 GT:GQ:DP .:245:32 ./.:145:22 +1 3106154 . C CT 459 PASS AN=4;AC=2 GT:GQ:DP 0/1:245:32 0/1:145:22 +1 3157410 . G T 46.7 q10 AN=4;AC=4 GT:GQ:DP 1/1:21:21 1/1:11:11 +1 3162006 . GAA G 206 PASS AN=4;AC=2 GT:GQ:DP 0/1:212:22 0/1:112:12 +1 3177144 . G . 364 PASS AN=4;AC=0 GT:GQ:DP 0/0:150:30 0/0:150:20 +1 3184885 . TAAAA TA,T 8.42 PASS AN=4;AC=2,2 GT:GQ:DP 1/2:22:20 1/2:12:10 +2 3199812 . G GTT,GT 291 PASS AN=4;AC=2,2 GT:GQ:DP 1/2:322:26 1/2:122:16 +3 3212016 . CTT C,CT 52.5 PASS AN=4;AC=2,2 GT:GQ:DP 1/2:91:26 1/2:11:16 +4 3258448 . TACACACAC T 123 PASS AN=4;AC=2 GT:GQ:DP 0/1:325:31 0/1:125:11 +4 3258449 . A C 123 PASS AN=4;AC=3 GT:GQ:DP 1/1:325:31 0/1:125:11 diff --git a/test/query.26.out b/test/query.26.out new file mode 100644 index 0000000..a0a1629 --- /dev/null +++ b/test/query.26.out @@ -0,0 +1 @@ +3000150 C T diff --git a/test/query.27.out b/test/query.27.out new file mode 100644 index 0000000..8d94f25 --- /dev/null +++ b/test/query.27.out @@ -0,0 +1,2 @@ +3000150 C T +3000153 C T,CA diff --git a/test/query.28.out b/test/query.28.out new file mode 100644 index 0000000..2eac8b3 --- /dev/null +++ b/test/query.28.out @@ -0,0 +1,4 @@ +3000151 C CA +3000152 C TA +3000153 C T,CA +3000154 C . diff --git a/test/query.29.out b/test/query.29.out new file mode 100644 index 0000000..ad5c344 --- /dev/null +++ b/test/query.29.out @@ -0,0 +1,3 @@ +3000151 C CA +3000152 C TA +3000154 C . diff --git a/test/query.3.out b/test/query.3.out new file mode 100644 index 0000000..85c3b81 --- /dev/null +++ b/test/query.3.out @@ -0,0 +1 @@ +1e+06,2e+06,3e+06 diff --git a/test/query.30.out b/test/query.30.out new file mode 100644 index 0000000..04142be --- /dev/null +++ b/test/query.30.out @@ -0,0 +1,19 @@ +301 8e-05 8e-05 0.00012 +304 8e-05 . 0.00012 +306 . 8e-05 0.00012 +307 . . 0.00012 +401 8e-05 0.00012 8e-05 +403 8e-05 0.00012 . +405 . 0.00012 . +406 . 0.00012 8e-05 +501 0.00012 8e-05 8e-05 +502 0.00012 . . +503 0.00012 8e-05 . +504 0.00012 . 8e-05 +1001 0.00012 0.00012 0.00012 +1002 0.00012 . . +1003 0.00012 0.00012 . +1004 0.00012 . 0.00012 +1005 . 0.00012 . +1006 . 0.00012 0.00012 +1007 . . 0.00012 diff --git a/test/query.31.out b/test/query.31.out new file mode 100644 index 0000000..a915702 --- /dev/null +++ b/test/query.31.out @@ -0,0 +1,16 @@ +201 8e-05 8e-05 8e-05 +202 8e-05 . . +203 8e-05 8e-05 . +204 8e-05 . 8e-05 +205 . 8e-05 . +206 . 8e-05 8e-05 +207 . . 8e-05 +302 8e-05 . . +303 8e-05 8e-05 . +305 . 8e-05 . +402 8e-05 . . +404 8e-05 . 8e-05 +407 . . 8e-05 +505 . 8e-05 . +506 . 8e-05 8e-05 +507 . . 8e-05 diff --git a/test/query.32.out b/test/query.32.out new file mode 100644 index 0000000..4e9b591 --- /dev/null +++ b/test/query.32.out @@ -0,0 +1,3 @@ + 11 11 11 + 11 11 11 + 11 11 11 diff --git a/test/query.33.out b/test/query.33.out new file mode 100644 index 0000000..dc178ca --- /dev/null +++ b/test/query.33.out @@ -0,0 +1,4 @@ +0/1 +0/2 +1/0 +2/0 diff --git a/test/query.4.out b/test/query.4.out new file mode 100644 index 0000000..4995c78 --- /dev/null +++ b/test/query.4.out @@ -0,0 +1 @@ +ABC,DEF,GHI,JKL,MNO,PQR diff --git a/test/query.5.out b/test/query.5.out new file mode 100644 index 0000000..34eb7c5 --- /dev/null +++ b/test/query.5.out @@ -0,0 +1,2 @@ +3106154 C CT +3212016 CTT C,CT diff --git a/test/query.6.out b/test/query.6.out new file mode 100644 index 0000000..a616d26 --- /dev/null +++ b/test/query.6.out @@ -0,0 +1,4 @@ +3062915 G C,T +3184885 TAAAA TA,T +3199812 G GTT,GT +3212016 CTT C,CT diff --git a/test/query.7.out b/test/query.7.out new file mode 100644 index 0000000..f476c62 --- /dev/null +++ b/test/query.7.out @@ -0,0 +1 @@ +3106154 0 diff --git a/test/query.8.out b/test/query.8.out new file mode 100644 index 0000000..f327bf8 --- /dev/null +++ b/test/query.8.out @@ -0,0 +1,3 @@ +3062915 -20,-5,-20 -10,-5,-20 +3062915 -20,-5,-20,-20,-5,-20 -10,-5,-20,-20,-5,-20 +3062915 -20,-5,-20 -10,-5,-20 diff --git a/test/query.9.out b/test/query.9.out new file mode 100644 index 0000000..7135f88 --- /dev/null +++ b/test/query.9.out @@ -0,0 +1 @@ +3162007 1X4M,1X3M1X diff --git a/test/query.filter-type.vcf b/test/query.filter-type.vcf new file mode 100644 index 0000000..07a45d0 --- /dev/null +++ b/test/query.filter-type.vcf @@ -0,0 +1,21 @@ +##fileformat=VCFv4.1 +##INFO= +##FORMAT= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FILTER= +##FILTER= +##contig= +##contig= +##contig= +##contig= +##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B +1 3000150 . C T 59.2 test . GT 0 0 +1 3000151 . C CA 59.2 test . GT 1 0 +1 3000152 . C TA 59.2 PASS . GT 0 1 +1 3000153 . C T,CA 59.2 PASS . GT 1 1 +1 3000154 . C . 59.2 PASS . GT 1 1 diff --git a/test/query.filter.2.vcf b/test/query.filter.2.vcf new file mode 100644 index 0000000..195e44d --- /dev/null +++ b/test/query.filter.2.vcf @@ -0,0 +1,14 @@ +##fileformat=VCFv4.3 +##FORMAT= +##contig= +##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A +1 3000150 . C T,A 59.2 PASS . GT ./. +1 3000151 . C T,A 59.2 PASS . GT 0/0 +1 3000152 . C T,A 59.2 PASS . GT 0/1 +1 3000153 . C T,A 59.2 PASS . GT 0/2 +1 3000154 . C T,A 59.2 PASS . GT 1/0 +1 3000155 . C T,A 59.2 PASS . GT 1/1 +1 3000156 . C T,A 59.2 PASS . GT 1/2 +1 3000157 . C T,A 59.2 PASS . GT 2/0 +1 3000158 . C T,A 59.2 PASS . GT 2/2 diff --git a/test/query.filter.vcf b/test/query.filter.vcf new file mode 100644 index 0000000..b43d70a --- /dev/null +++ b/test/query.filter.vcf @@ -0,0 +1,20 @@ +##fileformat=VCFv4.1 +##INFO= +##FORMAT= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FILTER= +##FILTER= +##contig= +##contig= +##contig= +##contig= +##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B +1 3000150 . C T 59.2 PASS . GT 0 0 +1 3000151 . C T 59.2 PASS . GT 1 0 +1 3000152 . C T 59.2 PASS . GT 0 1 +1 3000153 . C T 59.2 PASS . GT 1 1 diff --git a/test/query.out b/test/query.out new file mode 100644 index 0000000..119849c --- /dev/null +++ b/test/query.out @@ -0,0 +1,13 @@ +1 3062915 GTTT G 1,2,3,4 4 0/1 GTTT/G 0/1 GTTT/G +1 3062915 G C,T 1,2,3,4 4 0/1 G/C 0/2 G/T +1 3062915 GTT G 1,2,3,4 4 0/1 GTT/G 0/1 GTT/G +1 3106154 CAAA C . 0 . . ./. ./. +1 3106154 C CT . 4 0/1 C/CT 0/1 C/CT +1 3157410 G T . 4 1/1 T/T 1/1 T/T +1 3162006 GAA G . 4 0/1 GAA/G 0/1 GAA/G +1 3177144 G . . 4 0/0 G/G 0/0 G/G +1 3184885 TAAAA TA,T . 4 1/2 TA/T 1/2 TA/T +2 3199812 G GTT,GT . 4 1/2 GTT/GT 1/2 GTT/GT +3 3212016 CTT C,CT . 4 1/2 C/CT 1/2 C/CT +4 3258448 TACACACAC T . 4 0/1 TACACACAC/T 0/1 TACACACAC/T +4 3258449 A C . 4 1/1 C/C 0/1 A/C diff --git a/test/query.vcf b/test/query.vcf new file mode 100644 index 0000000..d2fffeb --- /dev/null +++ b/test/query.vcf @@ -0,0 +1,33 @@ +##fileformat=VCFv4.1 +##INFO= +##FORMAT= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FILTER= +##FILTER= +##contig= +##contig= +##contig= +##contig= +##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta +##readme=AAAAAA +##readme=BBBBBB +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT C D +1 3062915 id3D GTTT G 48.7 q10 DP4=1,2,3,4;AN=4;AC=2 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 0/1:109:25:-10,-5,-20 +1 3062915 idSNP G C,T 419 test TEST=5;DP4=1,2,3,4;AN=4;AC=1,1 GT:TT:GQ:DP:GL 0/1:0,1:409:35:-20,-5,-20,-20,-5,-20 0/2:0,1:109:35:-10,-5,-20,-20,-5,-20 +1 3062915 id2D GTT G 999 q10 DP4=1,2,3,4;AN=4;AC=2 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 0/1:109:25:-10,-5,-20 +1 3106154 . CAAA C 72.6 PASS AN=0;AC=0 GT:GQ:DP .:245:32 ./.:145:22 +1 3106154 . C CT 459 PASS AN=4;AC=2 GT:GQ:DP 0/1:245:32 0/1:145:22 +1 3157410 . G T 46.7 q10 AN=4;AC=4 GT:GQ:DP 1/1:21:21 1/1:11:11 +1 3162006 . GAA G 206 PASS AN=4;AC=2 GT:GQ:DP 0/1:212:22 0/1:112:12 +1 3177144 . G . 364 PASS AN=4;AC=0 GT:GQ:DP 0/0:150:30 0/0:150:20 +1 3184885 . TAAAA TA,T 8.42 PASS AN=4;AC=2,2 GT:GQ:DP 1/2:22:20 1/2:12:10 +2 3199812 . G GTT,GT 291 PASS AN=4;AC=2,2 GT:GQ:DP 1/2:322:26 1/2:122:16 +3 3212016 . CTT C,CT 52.5 PASS AN=4;AC=2,2 GT:GQ:DP 1/2:91:26 1/2:11:16 +4 3258448 . TACACACAC T 123 PASS AN=4;AC=2 GT:GQ:DP 0/1:325:31 0/1:125:11 +4 3258449 . A C 123 PASS AN=4;AC=3 GT:GQ:DP 1/1:325:31 0/1:125:11 diff --git a/test/ref.out b/test/ref.out new file mode 100644 index 0000000..7bee378 --- /dev/null +++ b/test/ref.out @@ -0,0 +1,30 @@ +##fileformat=VCFv4.2 +##FILTER= +##contig= +##contig= +##contig= +##contig= +##contig= +##contig= +#CHROM POS ID REF ALT QUAL FILTER INFO +1 105 . TAAACCCTA T,TAACCCTA 999 PASS . +2 1 . GGGCGTCTCATAGCTGGAGCAATGGCGAGCGCCTGGACAAGGGAGGGGAAGGGGTTCTTATTACTGACGCGGGTAGCCCCTACTGCTGTGTGGTTCCCCTATTTTTTTTTTTTTCTTTTTGAGACGGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGCACAATCTCGGCTCACTGCAAGCTCCACC ACG 999 PASS . +2 101 . A ATT 999 PASS . +2 114 . T TTC,TT 999 PASS . +2 115 . C T 999 PASS . +20 3 . G CT 999 PASS . +20 5 . TG CT 999 PASS . +20 5 . TGGG TAC,TG,TGGGG,AC . PASS . +20 59 . AG . 999 PASS . +20 81 . A C 999 PASS . +20 84 . G T 999 PASS . +20 95 . T A 999 PASS . +20 95 . TCACCG AAAAAA 999 PASS . +20 273 . C CAA,CAAA 999 PASS . +20 273 . C CAAAAAAAAAA 999 PASS . +20 273 . C CAA 999 PASS . +20 275 . A C,G 999 PASS . +3 10 . GTGGAC GTGGACACAC,GTGGACAC,GTGGACACACAC,GTGG,GTGGACACACACAC,ATGGACACACAC 999 PASS . +3 17 . CA C 999 PASS . +4 36 . TC C,TT,TTC 999 PASS . +5 21 . A AAG 999 PASS . diff --git a/test/ref.vcf b/test/ref.vcf new file mode 100644 index 0000000..e07cfde --- /dev/null +++ b/test/ref.vcf @@ -0,0 +1,30 @@ +##fileformat=VCFv4.2 +##FILTER= +##contig= +##contig= +##contig= +##contig= +##contig= +##contig= +#CHROM POS ID REF ALT QUAL FILTER INFO +1 105 . TAAACCCTA T,TAACCCTA 999 PASS . +2 1 . GGGCGTCTCATAGCTGGAGCAATGGCGAGCGCCTGGACAAGGGAGGGGAAGGGGTTCTTATTACTGACGCGGGTAGCCCCTACTGCTGTGTGGTTCCCCTATTTTTTTTTTTTTCTTTTTGAGACGGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGCACAATCTCGGCTCACTGCAAGCTCCACC ACG 999 PASS . +2 101 . N ATT 999 PASS . +2 114 . N TTC,TT 999 PASS . +2 115 . N T 999 PASS . +20 3 . N CT 999 PASS . +20 5 . NN CT 999 PASS . +20 5 . TGGG TAC,TG,TGGGG,AC . PASS . +20 59 . NN . 999 PASS . +20 81 . N C 999 PASS . +20 84 . N T 999 PASS . +20 95 . N A 999 PASS . +20 95 . TCACCG AAAAAA 999 PASS . +20 273 . N CAA,CAAA 999 PASS . +20 273 . N CAAAAAAAAAA 999 PASS . +20 273 . N CAA 999 PASS . +20 275 . N C,G 999 PASS . +3 10 . GTGGAC GTGGACACAC,GTGGACAC,GTGGACACACAC,GTGG,GTGGACACACACAC,ATGGACACACAC 999 PASS . +3 17 . CA C 999 PASS . +4 36 . TC C,TT,TTC 999 PASS . +5 21 . A AAG 999 PASS . diff --git a/test/regions.out b/test/regions.out new file mode 100644 index 0000000..ba45b84 --- /dev/null +++ b/test/regions.out @@ -0,0 +1,10 @@ +1 3062915 GTT,G +1 3062915 G,T +1 3106154 CA,C +1 3106154 C,T,CT +1 3157410 G,A +1 3162006 G,A +1 3184885 T,TA +2 3199815 C,T +3 3212016 C,A +3 3212036 C,A diff --git a/test/regions.tab b/test/regions.tab new file mode 100644 index 0000000..514dc36 --- /dev/null +++ b/test/regions.tab @@ -0,0 +1,8 @@ +1 3062915 3062915 +1 3106154 3106154 +1 3157410 3157410 +1 3162006 3162006 +1 3184885 3184885 +2 3199815 3199815 +3 3212016 3212016 +3 3212036 3212036 diff --git a/test/regions.vcf b/test/regions.vcf new file mode 100644 index 0000000..d5613c1 --- /dev/null +++ b/test/regions.vcf @@ -0,0 +1,29 @@ +##fileformat=VCFv4.1 +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FILTER= +##test= +##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta +##INFO= +##INFO= +##contig= +##contig= +##contig= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A +1 3062915 . GTT G 1806 q10 DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 +1 3062915 . G T 1806 q10 DP=35;DP4=1,2,3,4;AN=2;AC=1 GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 +1 3106154 . CA C 1792 PASS DP=32;AN=2;AC=1 GT:GQ:DP 0/1:245:32 +1 3106154 . C T,CT 1792 PASS DP=32;AN=2;AC=1 GT:GQ:DP 0/1:245:32 +1 3157410 . G A 628 q10 DP=21;AN=2;AC=2 GT:GQ:DP 1/1:21:21 +1 3162006 . G A 1016 PASS DP=22;AN=2;AC=1 GT:GQ:DP 0/1:212:22 +1 3177144 . GT G 727 PASS DP=30;AN=2;AC=1 GT:GQ:DP 0/1:150:30 +1 3184885 . T TA 246 PASS DP=10;AN=2;AC=1,1 GT:GQ:DP 1/2:12:10 +2 3199812 . G T 481 PASS DP=26;AN=2;AC=1,1 GT:GQ:DP 1/2:322:26 +2 3199815 . C T 481 PASS DP=26;AN=2;AC=1,1 GT:GQ:DP 1/2:322:26 +3 3212016 . C A 565 PASS DP=26;AN=2;AC=1,1 GT:GQ:DP 1/2:91:26 +3 3212026 . C A 565 PASS DP=26;AN=2;AC=1,1 GT:GQ:DP 1/2:91:26 +3 3212036 . C A 565 PASS DP=26;AN=2;AC=1,1 GT:GQ:DP 1/2:91:26 diff --git a/test/reheader.1.out b/test/reheader.1.out new file mode 100644 index 0000000..61d244d --- /dev/null +++ b/test/reheader.1.out @@ -0,0 +1,38 @@ +##fileformat=VCFv4.2 +##FILTER= +##INFO= +##FILTER= +##FORMAT= +##INFO= +##INFO= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##contig= +##contig= +##contig= +##contig= +##contig= +##contig= +##contig= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT AAA0001 BBB0002 +2 101 . ATTTTTTTTTTTTT ATTTTTTTTTTTTTTT 999 PASS INDEL;AN=4;AC=4 GT:DP 1/1:1 1/1:1 +2 114 . TC TTCC,TTC 999 PASS INDEL;AN=4;AC=2,2 GT:DP 1/2:1 1/2:1 +2 115 . C T 999 PASS INDEL;AN=4;AC=4 GT:DP 1/1:1 1/1:1 +20 3 . G CT 999 PASS INDEL;AN=4;AC=2 GT 0/1 0/1 +20 3 . GATG GACT 999 PASS INDEL;AN=4;AC=2 GT 1/0 1/0 +20 5 . TGGG TAC,TG,TGGGG,AC . PASS INDEL;AN=4;AC=2,2,0,0 GT:PL:DP 1/2:1,2,3,4,5,6,7,8,9,10,11,12,13,14,15:1 1/2:1,2,3,4,5,6,7,8,9,10,11,12,13,14,15:1 +20 59 . AG . 999 PASS AN=4 GT:PL:DP 0/0:0:4 0/0:0:4 +20 80 . CACAG CACAT 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 +20 81 . A C 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 +20 95 . TCACCG ACACCG 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 +20 95 . TCACCG AAAAAA 999 Test AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 +20 273 . CAAAAAAAAAAAAAAAAAAAAA CAAAAAAAAAAAAAAAAAAAAAAA,CAAAAAAAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=4;AC=2,2 GT:PL:DP 1/2:0,3,5,3,5,5:1 1/2:0,3,5,3,5,5:1 +20 274 . AAAAAAAAA AAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=0;AC=0 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 +20 278 . AAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=0;AC=0 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 +3 10 . GTGGAC GTGGACACAC,GTGGACAC,GTGGACACACAC,GTGG,GTGGACACACACAC,ATGGACACACAC 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 +3 15 . CACA CAC 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 +4 21 . ATTTTTTTTTTTTTTTC ATTTTTTTTTTTTTTC,ATTTTTTTTTTTTTTTT,ATTTTTTTTTTTTTTTTC 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 +5 22 . A AGA 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 diff --git a/test/reheader.1.out.bcf b/test/reheader.1.out.bcf new file mode 100644 index 0000000..c5a372d --- /dev/null +++ b/test/reheader.1.out.bcf @@ -0,0 +1,38 @@ +##fileformat=VCFv4.2 +##FILTER= +##INFO= +##INFO= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##contig= +##contig= +##contig= +##contig= +##contig= +##contig= +##FILTER= +##INFO= +##FORMAT= +##contig= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT AAA0001 BBB0002 +2 101 . ATTTTTTTTTTTTT ATTTTTTTTTTTTTTT 999 PASS INDEL;AN=4;AC=4 GT:DP 1/1:1 1/1:1 +2 114 . TC TTCC,TTC 999 PASS INDEL;AN=4;AC=2,2 GT:DP 1/2:1 1/2:1 +2 115 . C T 999 PASS INDEL;AN=4;AC=4 GT:DP 1/1:1 1/1:1 +20 3 . G CT 999 PASS INDEL;AN=4;AC=2 GT 0/1 0/1 +20 3 . GATG GACT 999 PASS INDEL;AN=4;AC=2 GT 1/0 1/0 +20 5 . TGGG TAC,TG,TGGGG,AC . PASS INDEL;AN=4;AC=2,2,0,0 GT:PL:DP 1/2:1,2,3,4,5,6,7,8,9,10,11,12,13,14,15:1 1/2:1,2,3,4,5,6,7,8,9,10,11,12,13,14,15:1 +20 59 . AG . 999 PASS AN=4 GT:PL:DP 0/0:0:4 0/0:0:4 +20 80 . CACAG CACAT 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 +20 81 . A C 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 +20 95 . TCACCG ACACCG 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 +20 95 . TCACCG AAAAAA 999 Test AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 +20 273 . CAAAAAAAAAAAAAAAAAAAAA CAAAAAAAAAAAAAAAAAAAAAAA,CAAAAAAAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=4;AC=2,2 GT:PL:DP 1/2:0,3,5,3,5,5:1 1/2:0,3,5,3,5,5:1 +20 274 . AAAAAAAAA AAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=0;AC=0 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 +20 278 . AAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=0;AC=0 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 +3 10 . GTGGAC GTGGACACAC,GTGGACAC,GTGGACACACAC,GTGG,GTGGACACACACAC,ATGGACACACAC 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 +3 15 . CACA CAC 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 +4 21 . ATTTTTTTTTTTTTTTC ATTTTTTTTTTTTTTC,ATTTTTTTTTTTTTTTT,ATTTTTTTTTTTTTTTTC 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 +5 22 . A AGA 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 diff --git a/test/reheader.2.out b/test/reheader.2.out new file mode 100644 index 0000000..6729715 --- /dev/null +++ b/test/reheader.2.out @@ -0,0 +1,55 @@ +##fileformat=VCFv4.1 +##FILTER= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##contig= +##contig= +##contig= +##contig= +##contig= +##contig= +##FILTER= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT AAA BBB +2 101 . ATTTTTTTTTTTTT ATTTTTTTTTTTTTTT 999 PASS INDEL;AN=4;AC=4 GT:DP 1/1:1 1/1:1 +2 114 . TC TTCC,TTC 999 PASS INDEL;AN=4;AC=2,2 GT:DP 1/2:1 1/2:1 +2 115 . C T 999 PASS INDEL;AN=4;AC=4 GT:DP 1/1:1 1/1:1 +20 3 . G CT 999 PASS INDEL;AN=4;AC=2 GT 0/1 0/1 +20 3 . GATG GACT 999 PASS INDEL;AN=4;AC=2 GT 1/0 1/0 +20 5 . TGGG TAC,TG,TGGGG,AC . PASS INDEL;AN=4;AC=2,2,0,0 GT:PL:DP 1/2:1,2,3,4,5,6,7,8,9,10,11,12,13,14,15:1 1/2:1,2,3,4,5,6,7,8,9,10,11,12,13,14,15:1 +20 59 . AG . 999 PASS AN=4 GT:PL:DP 0/0:0:4 0/0:0:4 +20 80 . CACAG CACAT 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 +20 81 . A C 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 +20 95 . TCACCG ACACCG 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 +20 95 . TCACCG AAAAAA 999 Test AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 +20 273 . CAAAAAAAAAAAAAAAAAAAAA CAAAAAAAAAAAAAAAAAAAAAAA,CAAAAAAAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=4;AC=2,2 GT:PL:DP 1/2:0,3,5,3,5,5:1 1/2:0,3,5,3,5,5:1 +20 274 . AAAAAAAAA AAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=0;AC=0 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 +20 278 . AAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=0;AC=0 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 +3 10 . GTGGAC GTGGACACAC,GTGGACAC,GTGGACACACAC,GTGG,GTGGACACACACAC,ATGGACACACAC 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 +3 15 . CACA CAC 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 +4 21 . ATTTTTTTTTTTTTTTC ATTTTTTTTTTTTTTC,ATTTTTTTTTTTTTTTT,ATTTTTTTTTTTTTTTTC 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 +5 22 . A AGA 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 diff --git a/test/reheader.3.out b/test/reheader.3.out new file mode 100644 index 0000000..c520746 --- /dev/null +++ b/test/reheader.3.out @@ -0,0 +1,55 @@ +##fileformat=VCFv4.1 +##FILTER= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##contig= +##contig= +##contig= +##contig= +##contig= +##contig= +##FILTER= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A AA BB B +2 101 . ATTTTTTTTTTTTT ATTTTTTTTTTTTTTT 999 PASS INDEL;AN=4;AC=4 GT:DP 1/1:1 1/1:1 +2 114 . TC TTCC,TTC 999 PASS INDEL;AN=4;AC=2,2 GT:DP 1/2:1 1/2:1 +2 115 . C T 999 PASS INDEL;AN=4;AC=4 GT:DP 1/1:1 1/1:1 +20 3 . G CT 999 PASS INDEL;AN=4;AC=2 GT 0/1 0/1 +20 3 . GATG GACT 999 PASS INDEL;AN=4;AC=2 GT 1/0 1/0 +20 5 . TGGG TAC,TG,TGGGG,AC . PASS INDEL;AN=4;AC=2,2,0,0 GT:PL:DP 1/2:1,2,3,4,5,6,7,8,9,10,11,12,13,14,15:1 1/2:1,2,3,4,5,6,7,8,9,10,11,12,13,14,15:1 +20 59 . AG . 999 PASS AN=4 GT:PL:DP 0/0:0:4 0/0:0:4 +20 80 . CACAG CACAT 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 +20 81 . A C 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 +20 95 . TCACCG ACACCG 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 +20 95 . TCACCG AAAAAA 999 Test AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 +20 273 . CAAAAAAAAAAAAAAAAAAAAA CAAAAAAAAAAAAAAAAAAAAAAA,CAAAAAAAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=4;AC=2,2 GT:PL:DP 1/2:0,3,5,3,5,5:1 1/2:0,3,5,3,5,5:1 +20 274 . AAAAAAAAA AAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=0;AC=0 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 +20 278 . AAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=0;AC=0 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 +3 10 . GTGGAC GTGGACACAC,GTGGACAC,GTGGACACACAC,GTGG,GTGGACACACACAC,ATGGACACACAC 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 +3 15 . CACA CAC 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 +4 21 . ATTTTTTTTTTTTTTTC ATTTTTTTTTTTTTTC,ATTTTTTTTTTTTTTTT,ATTTTTTTTTTTTTTTTC 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 +5 22 . A AGA 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 diff --git a/test/reheader.4.out b/test/reheader.4.out new file mode 100644 index 0000000..8b7c1ed --- /dev/null +++ b/test/reheader.4.out @@ -0,0 +1,55 @@ +##fileformat=VCFv4.1 +##FILTER= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##contig= +##contig= +##contig= +##contig= +##contig= +##contig= +##FILTER= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT XY00001 BB +2 101 . ATTTTTTTTTTTTT ATTTTTTTTTTTTTTT 999 PASS INDEL;AN=4;AC=4 GT:DP 1/1:1 1/1:1 +2 114 . TC TTCC,TTC 999 PASS INDEL;AN=4;AC=2,2 GT:DP 1/2:1 1/2:1 +2 115 . C T 999 PASS INDEL;AN=4;AC=4 GT:DP 1/1:1 1/1:1 +20 3 . G CT 999 PASS INDEL;AN=4;AC=2 GT 0/1 0/1 +20 3 . GATG GACT 999 PASS INDEL;AN=4;AC=2 GT 1/0 1/0 +20 5 . TGGG TAC,TG,TGGGG,AC . PASS INDEL;AN=4;AC=2,2,0,0 GT:PL:DP 1/2:1,2,3,4,5,6,7,8,9,10,11,12,13,14,15:1 1/2:1,2,3,4,5,6,7,8,9,10,11,12,13,14,15:1 +20 59 . AG . 999 PASS AN=4 GT:PL:DP 0/0:0:4 0/0:0:4 +20 80 . CACAG CACAT 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 +20 81 . A C 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 +20 95 . TCACCG ACACCG 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 +20 95 . TCACCG AAAAAA 999 Test AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 +20 273 . CAAAAAAAAAAAAAAAAAAAAA CAAAAAAAAAAAAAAAAAAAAAAA,CAAAAAAAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=4;AC=2,2 GT:PL:DP 1/2:0,3,5,3,5,5:1 1/2:0,3,5,3,5,5:1 +20 274 . AAAAAAAAA AAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=0;AC=0 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 +20 278 . AAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=0;AC=0 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 +3 10 . GTGGAC GTGGACACAC,GTGGACAC,GTGGACACACAC,GTGG,GTGGACACACACAC,ATGGACACACAC 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 +3 15 . CACA CAC 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 +4 21 . ATTTTTTTTTTTTTTTC ATTTTTTTTTTTTTTC,ATTTTTTTTTTTTTTTT,ATTTTTTTTTTTTTTTTC 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 +5 22 . A AGA 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 diff --git a/test/reheader.empty.hdr b/test/reheader.empty.hdr new file mode 100644 index 0000000..cd5a018 --- /dev/null +++ b/test/reheader.empty.hdr @@ -0,0 +1,7 @@ +##fileformat=VCFv4.1 +##contig= +##contig= +##contig= +##contig= +##contig= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA00001 NA00002 NA00003 diff --git a/test/reheader.empty.out b/test/reheader.empty.out new file mode 100644 index 0000000..cbc236b --- /dev/null +++ b/test/reheader.empty.out @@ -0,0 +1,8 @@ +##fileformat=VCFv4.1 +##FILTER= +##contig= +##contig= +##contig= +##contig= +##contig= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA00001 NA00002 NA00003 diff --git a/test/reheader.hdr b/test/reheader.hdr new file mode 100644 index 0000000..ab9e808 --- /dev/null +++ b/test/reheader.hdr @@ -0,0 +1,19 @@ +##fileformat=VCFv4.2 +##INFO= +##FILTER= +##FORMAT= +##INFO= +##INFO= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##contig= +##contig= +##contig= +##contig= +##contig= +##contig= +##contig= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT AAA0001 BBB0002 diff --git a/test/reheader.samples b/test/reheader.samples new file mode 100644 index 0000000..b384270 --- /dev/null +++ b/test/reheader.samples @@ -0,0 +1,2 @@ +AAA +BBB diff --git a/test/reheader.samples2 b/test/reheader.samples2 new file mode 100644 index 0000000..884cb11 --- /dev/null +++ b/test/reheader.samples2 @@ -0,0 +1,2 @@ +XY00002 BBB +XY00001 AAA diff --git a/test/reheader.samples3 b/test/reheader.samples3 new file mode 100644 index 0000000..b8f8700 --- /dev/null +++ b/test/reheader.samples3 @@ -0,0 +1,2 @@ +XY00002 BB\ B +XY00001 A\ AA diff --git a/test/reheader.samples4 b/test/reheader.samples4 new file mode 100644 index 0000000..dcda975 --- /dev/null +++ b/test/reheader.samples4 @@ -0,0 +1 @@ +XY00002 BB diff --git a/test/reheader.vcf b/test/reheader.vcf new file mode 100644 index 0000000..3c4f72e --- /dev/null +++ b/test/reheader.vcf @@ -0,0 +1,54 @@ +##fileformat=VCFv4.1 +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##contig= +##contig= +##contig= +##contig= +##contig= +##contig= +##FILTER= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT XY00001 XY00002 +2 101 . ATTTTTTTTTTTTT ATTTTTTTTTTTTTTT 999 PASS INDEL;AN=4;AC=4 GT:DP 1/1:1 1/1:1 +2 114 . TC TTCC,TTC 999 PASS INDEL;AN=4;AC=2,2 GT:DP 1/2:1 1/2:1 +2 115 . C T 999 PASS INDEL;AN=4;AC=4 GT:DP 1/1:1 1/1:1 +20 3 . G CT 999 PASS INDEL;AN=4;AC=2 GT 0/1 0/1 +20 3 . GATG GACT 999 PASS INDEL;AN=4;AC=2 GT 1/0 1/0 +20 5 . TGGG TAC,TG,TGGGG,AC . PASS INDEL;AN=4;AC=2,2,0,0 GT:PL:DP 1/2:1,2,3,4,5,6,7,8,9,10,11,12,13,14,15:1 1/2:1,2,3,4,5,6,7,8,9,10,11,12,13,14,15:1 +20 59 . AG . 999 PASS AN=4 GT:PL:DP 0/0:0:4 0/0:0:4 +20 80 . CACAG CACAT 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 +20 81 . A C 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 +20 95 . TCACCG ACACCG 999 PASS AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 +20 95 . TCACCG AAAAAA 999 Test AN=4;AC=2 GT:PL:DP 0/1:255,0,255:13 0/1:255,0,255:13 +20 273 . CAAAAAAAAAAAAAAAAAAAAA CAAAAAAAAAAAAAAAAAAAAAAA,CAAAAAAAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=4;AC=2,2 GT:PL:DP 1/2:0,3,5,3,5,5:1 1/2:0,3,5,3,5,5:1 +20 274 . AAAAAAAAA AAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=0;AC=0 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 +20 278 . AAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAA 999 PASS INDEL;AN=0;AC=0 GT:PL:DP ./.:0,0,0:0 ./.:0,0,0:0 +3 10 . GTGGAC GTGGACACAC,GTGGACAC,GTGGACACACAC,GTGG,GTGGACACACACAC,ATGGACACACAC 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 +3 15 . CACA CAC 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 +4 21 . ATTTTTTTTTTTTTTTC ATTTTTTTTTTTTTTC,ATTTTTTTTTTTTTTTT,ATTTTTTTTTTTTTTTTC 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 +5 22 . A AGA 999 PASS INDEL;AN=0 GT:DP ./.:0 ./.:0 diff --git a/test/setGT.1.out b/test/setGT.1.out new file mode 100644 index 0000000..e2746b0 --- /dev/null +++ b/test/setGT.1.out @@ -0,0 +1,35 @@ +##fileformat=VCFv4.1 +##FILTER= +##INFO= +##FORMAT= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FILTER= +##FILTER= +##contig= +##contig= +##contig= +##contig= +##test= +##readme=AAAAAA +##readme=BBBBBB +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B +1 3000150 . C T 59.2 PASS . GT:GQ ./.:245 0/1:245 +1 3000151 . C T 59.2 PASS . GT:DP:GQ 1/0:32:245 ./.:32:245 +1 3062915 id3D GTTT G 12.9 q10 DP4=1,2,3,4;INDEL;STR=test GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 0/1:409:35:-20,-5,-20 +1 3062915 idSNP G T,C 12.6 test TEST=5;DP4=1,2,3,4 GT:TT:GQ:DP:GL 0/1:0,1:409:35:-20,-5,-20,-20,-5,-20 2:0,1:409:35:-20,-5,-20 +1 3106154 . CAAA C 342 PASS . GT:GQ:DP ./.:245:32 ./.:245:30 +1 3106154 . C CT 59.2 PASS . GT:GQ:DP ./.:245:32 ./.:245:30 +1 3157410 . GA G 90.6 q10 . GT:GQ:DP 1/1:21:21 1/1:21:21 +1 3162006 . GAA G 60.2 PASS . GT:GQ:DP ./.:212:22 ./.:212:22 +1 3177144 . G T 45 PASS . GT:GQ:DP 0/0:150:30 0/0:150:30 +1 3177144 . G . 45 PASS . GT:GQ:DP 0/0:150:30 0/0:150:30 +1 3184885 . TAAAA TA,T 61.5 PASS . GT:GQ:DP ./.:12:10 ./.:12:10 +2 3199812 . G GTT,GT 82.7 PASS . GT:GQ:DP ./.:322:26 ./.:322:26 +3 3212016 . CTT C,CT 79 PASS . GT:GQ:DP ./.:91:26 ./.:91:26 +4 3258448 . TACACACAC T 59.9 PASS . GT:GQ:DP ./.:325:31 ./.:325:31 diff --git a/test/setGT.vcf b/test/setGT.vcf new file mode 100644 index 0000000..17e7877 --- /dev/null +++ b/test/setGT.vcf @@ -0,0 +1,35 @@ +##fileformat=VCFv4.1 +##FILTER= +##INFO= +##FORMAT= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FILTER= +##FILTER= +##contig= +##contig= +##contig= +##contig= +##test= +##readme=AAAAAA +##readme=BBBBBB +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B +1 3000150 . C T 59.2 PASS . GT:GQ ./.:245 0/1:245 +1 3000151 . C T 59.2 PASS . GT:DP:GQ 1/0:32:245 ./.:32:245 +1 3062915 id3D GTTT G 12.9 q10 DP4=1,2,3,4;INDEL;STR=test GT:GQ:DP:GL 0/1:409:35:-20,-5,-20 0/1:409:35:-20,-5,-20 +1 3062915 idSNP G T,C 12.6 test TEST=5;DP4=1,2,3,4 GT:TT:GQ:DP:GL 0/1:0,1:409:35:-20,-5,-20,-20,-5,-20 2:0,1:409:35:-20,-5,-20 +1 3106154 . CAAA C 342 PASS . GT:GQ:DP ./.:245:32 ./.:245:30 +1 3106154 . C CT 59.2 PASS . GT:GQ:DP ./.:245:32 ./.:245:30 +1 3157410 . GA G 90.6 q10 . GT:GQ:DP 1/1:21:21 1/1:21:21 +1 3162006 . GAA G 60.2 PASS . GT:GQ:DP ./.:212:22 ./.:212:22 +1 3177144 . G T 45 PASS . GT:GQ:DP ./.:150:30 ./.:150:30 +1 3177144 . G . 45 PASS . GT:GQ:DP ./.:150:30 ./.:150:30 +1 3184885 . TAAAA TA,T 61.5 PASS . GT:GQ:DP ./.:12:10 ./.:12:10 +2 3199812 . G GTT,GT 82.7 PASS . GT:GQ:DP ./.:322:26 ./.:322:26 +3 3212016 . CTT C,CT 79 PASS . GT:GQ:DP ./.:91:26 ./.:91:26 +4 3258448 . TACACACAC T 59.9 PASS . GT:GQ:DP ./.:325:31 ./.:325:31 diff --git a/test/stats.B.chk b/test/stats.B.chk new file mode 100644 index 0000000..3245562 --- /dev/null +++ b/test/stats.B.chk @@ -0,0 +1,87 @@ +SN 0 number of samples: 3 +SN 1 number of samples: 3 +SN 0 number of records: 0 +SN 0 number of no-ALTs: 0 +SN 0 number of SNPs: 0 +SN 0 number of MNPs: 0 +SN 0 number of indels: 0 +SN 0 number of others: 0 +SN 0 number of multiallelic sites: 0 +SN 0 number of multiallelic SNP sites: 0 +SN 1 number of records: 0 +SN 1 number of no-ALTs: 0 +SN 1 number of SNPs: 0 +SN 1 number of MNPs: 0 +SN 1 number of indels: 0 +SN 1 number of others: 0 +SN 1 number of multiallelic sites: 0 +SN 1 number of multiallelic SNP sites: 0 +SN 2 number of records: 4 +SN 2 number of no-ALTs: 0 +SN 2 number of SNPs: 4 +SN 2 number of MNPs: 0 +SN 2 number of indels: 0 +SN 2 number of others: 0 +SN 2 number of multiallelic sites: 0 +SN 2 number of multiallelic SNP sites: 0 +TSTV 0 0 0 0.00 0 0 0.00 +TSTV 1 0 0 0.00 0 0 0.00 +TSTV 2 3 1 3.00 3 1 3.00 +SiS 0 1 0 0 0 0 0 0 0 +SiS 1 1 0 0 0 0 0 0 0 +SiS 2 1 1 0 1 0 0 0 0 +AF 2 0.000000 1 0 1 0 0 0 0 +AF 2 0.490000 3 3 0 0 0 0 0 +QUAL 2 998 4 3 1 0 +ST 0 A>C 0 +ST 0 A>G 0 +ST 0 A>T 0 +ST 0 C>A 0 +ST 0 C>G 0 +ST 0 C>T 0 +ST 0 G>A 0 +ST 0 G>C 0 +ST 0 G>T 0 +ST 0 T>A 0 +ST 0 T>C 0 +ST 0 T>G 0 +ST 1 A>C 0 +ST 1 A>G 0 +ST 1 A>T 0 +ST 1 C>A 0 +ST 1 C>G 0 +ST 1 C>T 0 +ST 1 G>A 0 +ST 1 G>C 0 +ST 1 G>T 0 +ST 1 T>A 0 +ST 1 T>C 0 +ST 1 T>G 0 +ST 2 A>C 0 +ST 2 A>G 0 +ST 2 A>T 0 +ST 2 C>A 0 +ST 2 C>G 0 +ST 2 C>T 0 +ST 2 G>A 3 +ST 2 G>C 0 +ST 2 G>T 1 +ST 2 T>A 0 +ST 2 T>C 0 +ST 2 T>G 0 +SN 2 number of samples: 1 +GCsAF 2 0.490000 0 1 0 0 2 0 0 3 +NRDs 2 75.000000 0.000000 75.000000 0.000000 +NRDi 2 0.000000 0.000000 0.000000 0.000000 +GCsS 2 B 75.000 0 1 0 0 3 0 0 +GCiS 2 B 0.000 0 0 0 0 0 0 0 +GCTs B 0 0 0 0 0 2 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +GCTi B 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +PSC 0 B 0 0 0 0 0 0 0.0 0 +PSC 1 B 0 0 0 0 0 0 0.0 0 +PSC 2 B 0 0 4 3 1 0 0.0 4 +PSI 0 B 0 0 0 0.00 0 0 +PSI 1 B 0 0 0 0.00 0 0 +PSI 2 B 0 0 0 0.00 0 0 +HWE 2 0.000000 1 0.990000 0.990000 0.990000 +HWE 2 0.490000 3 0.990000 0.990000 0.990000 diff --git a/test/stats.a.vcf b/test/stats.a.vcf new file mode 100644 index 0000000..f48602f --- /dev/null +++ b/test/stats.a.vcf @@ -0,0 +1,9 @@ +##fileformat=VCFv4.2 +##FORMAT= +##contig= +##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B C +1 1000 . G A . PASS . GT 0/0 0/1 1/1 +1 1001 . G A . PASS . GT 0/0 0/1 1/1 +1 1002 . G A . PASS . GT 0/0 0/1 1/1 +1 1003 . G T . PASS . GT 0/0 0/1 0/0 diff --git a/test/stats.b.vcf b/test/stats.b.vcf new file mode 100644 index 0000000..1466c63 --- /dev/null +++ b/test/stats.b.vcf @@ -0,0 +1,9 @@ +##fileformat=VCFv4.2 +##FORMAT= +##contig= +##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B C +1 1000 . G A . PASS . GT 0/1 0/0 0/0 +1 1001 . G A . PASS . GT 0/0 0/0 0/0 +1 1002 . G A . PASS . GT 0/0 0/1 0/0 +1 1003 . G T . PASS . GT 1/1 1/1 1/1 diff --git a/test/stats.chk b/test/stats.chk new file mode 100644 index 0000000..af03c3e --- /dev/null +++ b/test/stats.chk @@ -0,0 +1,107 @@ +SN 0 number of samples: 3 +SN 1 number of samples: 3 +SN 0 number of records: 0 +SN 0 number of no-ALTs: 0 +SN 0 number of SNPs: 0 +SN 0 number of MNPs: 0 +SN 0 number of indels: 0 +SN 0 number of others: 0 +SN 0 number of multiallelic sites: 0 +SN 0 number of multiallelic SNP sites: 0 +SN 1 number of records: 0 +SN 1 number of no-ALTs: 0 +SN 1 number of SNPs: 0 +SN 1 number of MNPs: 0 +SN 1 number of indels: 0 +SN 1 number of others: 0 +SN 1 number of multiallelic sites: 0 +SN 1 number of multiallelic SNP sites: 0 +SN 2 number of records: 4 +SN 2 number of no-ALTs: 0 +SN 2 number of SNPs: 4 +SN 2 number of MNPs: 0 +SN 2 number of indels: 0 +SN 2 number of others: 0 +SN 2 number of multiallelic sites: 0 +SN 2 number of multiallelic SNP sites: 0 +TSTV 0 0 0 0.00 0 0 0.00 +TSTV 1 0 0 0.00 0 0 0.00 +TSTV 2 3 1 3.00 3 1 3.00 +SiS 0 1 0 0 0 0 0 0 0 +SiS 1 1 0 0 0 0 0 0 0 +SiS 2 1 1 0 1 0 0 0 0 +AF 2 0.000000 1 0 1 0 0 0 0 +AF 2 0.490000 3 3 0 0 0 0 0 +QUAL 2 998 4 3 1 0 +ST 0 A>C 0 +ST 0 A>G 0 +ST 0 A>T 0 +ST 0 C>A 0 +ST 0 C>G 0 +ST 0 C>T 0 +ST 0 G>A 0 +ST 0 G>C 0 +ST 0 G>T 0 +ST 0 T>A 0 +ST 0 T>C 0 +ST 0 T>G 0 +ST 1 A>C 0 +ST 1 A>G 0 +ST 1 A>T 0 +ST 1 C>A 0 +ST 1 C>G 0 +ST 1 C>T 0 +ST 1 G>A 0 +ST 1 G>C 0 +ST 1 G>T 0 +ST 1 T>A 0 +ST 1 T>C 0 +ST 1 T>G 0 +ST 2 A>C 0 +ST 2 A>G 0 +ST 2 A>T 0 +ST 2 C>A 0 +ST 2 C>G 0 +ST 2 C>T 0 +ST 2 G>A 3 +ST 2 G>C 0 +ST 2 G>T 1 +ST 2 T>A 0 +ST 2 T>C 0 +ST 2 T>G 0 +SN 2 number of samples: 3 +GCsAF 2 0.490000 2 1 0 1 2 3 0.107143 9 +NRDs 2 90.000000 60.000000 75.000000 100.000000 +NRDi 2 0.000000 0.000000 0.000000 0.000000 +GCsS 2 A 100.000 2 0 0 2 0 0 0 +GCsS 2 B 75.000 0 1 0 0 3 0 0 +GCsS 2 C 100.000 0 0 0 1 0 3 1.000000 +GCiS 2 A 0.000 0 0 0 0 0 0 0 +GCiS 2 B 0.000 0 0 0 0 0 0 0 +GCiS 2 C 0.000 0 0 0 0 0 0 0 +GCTs A 2 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +GCTs B 0 0 0 0 0 2 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +GCTs C 0 0 1 0 0 0 0 0 0 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +GCTi A 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +GCTi B 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +GCTi C 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +PSC 0 A 0 0 0 0 0 0 0.0 0 +PSC 0 B 0 0 0 0 0 0 0.0 0 +PSC 0 C 0 0 0 0 0 0 0.0 0 +PSC 1 A 0 0 0 0 0 0 0.0 0 +PSC 1 B 0 0 0 0 0 0 0.0 0 +PSC 1 C 0 0 0 0 0 0 0.0 0 +PSC 2 A 4 0 0 0 0 0 0.0 0 +PSC 2 B 0 0 4 3 1 0 0.0 1 +PSC 2 C 1 3 0 3 0 0 0.0 0 +PSI 0 A 0 0 0 0.00 0 0 +PSI 0 B 0 0 0 0.00 0 0 +PSI 0 C 0 0 0 0.00 0 0 +PSI 1 A 0 0 0 0.00 0 0 +PSI 1 B 0 0 0 0.00 0 0 +PSI 1 C 0 0 0 0.00 0 0 +PSI 2 A 0 0 0 0.00 0 0 +PSI 2 B 0 0 0 0.00 0 0 +PSI 2 C 0 0 0 0.00 0 0 +HWE 2 0.000000 1 0.330000 0.330000 0.330000 +HWE 2 0.490000 3 0.330000 0.330000 0.330000 diff --git a/test/tabix.1.3000151.out b/test/tabix.1.3000151.out new file mode 100644 index 0000000..e9d5c87 --- /dev/null +++ b/test/tabix.1.3000151.out @@ -0,0 +1 @@ +1 3000151 . C T 59.2 PASS AN=4;AC=2 GT:DP:GQ 0/1:32:245 0/1:32:245 diff --git a/test/tabix.2.3199812.out b/test/tabix.2.3199812.out new file mode 100644 index 0000000..be2f66e --- /dev/null +++ b/test/tabix.2.3199812.out @@ -0,0 +1 @@ +2 3199812 . G GTT,GT 82.7 PASS AN=4;AC=2,2 GT:GQ:DP 1/2:322:26 1/2:322:26 diff --git a/test/test-rbuf.c b/test/test-rbuf.c new file mode 100644 index 0000000..5c0480f --- /dev/null +++ b/test/test-rbuf.c @@ -0,0 +1,75 @@ +/* test/test-rbuf.c -- rbuf_t test harness. + + Copyright (C) 2014 Genome Research Ltd. + + Author: Petr Danecek + +Permission is hereby granted, free of charge, to any person obtaining a copy +of this software and associated documentation files (the "Software"), to deal +in the Software without restriction, including without limitation the rights +to use, copy, modify, merge, publish, distribute, sublicense, and/or sell +copies of the Software, and to permit persons to whom the Software is +furnished to do so, subject to the following conditions: + +The above copyright notice and this permission notice shall be included in +all copies or substantial portions of the Software. + +THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL +THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER +LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING +FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER +DEALINGS IN THE SOFTWARE. */ + +#include +#include +#include "rbuf.h" + +void debug_print(rbuf_t *rbuf, int *dat) +{ + int i; + for (i=-1; rbuf_next(rbuf, &i); ) printf(" %2d", i); + printf("\n"); + for (i=-1; rbuf_next(rbuf, &i); ) printf(" %2d", dat[i]); + printf("\n"); +} + +int main(int argc, char **argv) +{ + int i, j, *dat = (int*)calloc(10,sizeof(int)); + rbuf_t rbuf; + rbuf_init(&rbuf,10); + + rbuf.f = 5; // force wrapping + for (i=0; i<9; i++) + { + j = rbuf_append(&rbuf); + dat[j] = i+1; + } + printf("Inserted 1-9 starting at offset 5:\n"); + debug_print(&rbuf, dat); + + i = rbuf_kth(&rbuf, 3); + printf("4th is %d\n", dat[i]); + + printf("Deleting 1-2:\n"); + rbuf_shift_n(&rbuf, 2); + debug_print(&rbuf, dat); + + printf("Prepending 0-8:\n"); + for (i=0; i<9; i++) + { + j = rbuf_prepend(&rbuf); + dat[j] = i; + } + debug_print(&rbuf, dat); + + printf("Expanding:\n"); + rbuf_expand0(&rbuf,int,rbuf.n+1,dat); + debug_print(&rbuf, dat); + + free(dat); + return 0; +} + diff --git a/test/test-regidx.c b/test/test-regidx.c new file mode 100644 index 0000000..d318fb4 --- /dev/null +++ b/test/test-regidx.c @@ -0,0 +1,374 @@ +/* test/test-regidx.c -- Regions index test harness. + + gcc -g -Wall -O0 -I. -I../htslib/ -L../htslib regidx.c -o test-regidx test-regidx.c -lhts + + Copyright (C) 2014 Genome Research Ltd. + + Author: Petr Danecek + + Permission is hereby granted, free of charge, to any person obtaining a copy + of this software and associated documentation files (the "Software"), to deal + in the Software without restriction, including without limitation the rights + to use, copy, modify, merge, publish, distribute, sublicense, and/or sell + copies of the Software, and to permit persons to whom the Software is + furnished to do so, subject to the following conditions: + + The above copyright notice and this permission notice shall be included in + all copies or substantial portions of the Software. + + THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR + IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, + FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE + AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER + LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, + OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN + THE SOFTWARE. +*/ + +#include +#include +#include +#include +#include +#include +#include +#include +#include "regidx.h" + +static int verbose = 0; + +void debug(const char *format, ...) +{ + if ( verbose<2 ) return; + va_list ap; + va_start(ap, format); + vfprintf(stderr, format, ap); + va_end(ap); +} +void info(const char *format, ...) +{ + if ( verbose<1 ) return; + va_list ap; + va_start(ap, format); + vfprintf(stderr, format, ap); + va_end(ap); +} +void error(const char *format, ...) +{ + va_list ap; + va_start(ap, format); + vfprintf(stderr, format, ap); + va_end(ap); + exit(-1); +} + +int custom_parse(const char *line, char **chr_beg, char **chr_end, uint32_t *beg, uint32_t *end, void *payload, void *usr) +{ + // Use the standard parser for CHROM,FROM,TO + int i, ret = regidx_parse_tab(line,chr_beg,chr_end,beg,end,NULL,NULL); + if ( ret!=0 ) return ret; + + // Skip the fields that were parsed above + char *ss = (char*) line; + while ( *ss && isspace(*ss) ) ss++; + for (i=0; i<3; i++) + { + while ( *ss && !isspace(*ss) ) ss++; + if ( !*ss ) return -2; // wrong number of fields + while ( *ss && isspace(*ss) ) ss++; + } + if ( !*ss ) return -2; + + // Parse the payload + char *se = ss; + while ( *se && !isspace(*se) ) se++; + char **dat = (char**) payload; + *dat = (char*) malloc(se-ss+1); + memcpy(*dat,ss,se-ss+1); + (*dat)[se-ss] = 0; + return 0; +} +void custom_free(void *payload) +{ + char **dat = (char**)payload; + free(*dat); +} + +void test_sequential_access(void) +{ + // Init index with no file name, we will insert the regions manually + regidx_t *idx = regidx_init(NULL,custom_parse,custom_free,sizeof(char*),NULL); + if ( !idx ) error("init failed\n"); + + // Insert regions + kstring_t str = {0,0,0}; + int i, n = 10; + for (i=0; ibeg!=itr->end || itr->beg+1!=10*(i+1) ) error("listing failed, expected %d, found %d\n",10*(i+1),itr->beg+1); + str.l = 0; + ksprintf(&str,"%d",itr->beg+1); + if ( strcmp(regitr_payload(itr,char*),str.s) ) error("listing failed, expected payload \"%s\", found \"%s\"\n",str.s,regitr_payload(itr,char*)); + i++; + } + if ( i!=n ) error("Expected %d regions, listed %d\n", n,i); + debug("ok: listed %d regions\n", n); + + // Clean up + regitr_destroy(itr); + regidx_destroy(idx); + free(str.s); +} + +void test_custom_payload(void) +{ + // Init index with no file name, we will insert the regions manually + regidx_t *idx = regidx_init(NULL,custom_parse,custom_free,sizeof(char*),NULL); + if ( !idx ) error("init failed\n"); + + // Insert regions + char *line; + line = "1 10000000 10000000 1:10000000-10000000"; if ( regidx_insert(idx,line)!=0 ) error("insert failed: %s\n", line); + line = "1 20000000 20000001 1:20000000-20000001"; if ( regidx_insert(idx,line)!=0 ) error("insert failed: %s\n", line); + line = "1 20000002 20000002 1:20000002-20000002"; if ( regidx_insert(idx,line)!=0 ) error("insert failed: %s\n", line); + line = "1 30000000 30000000 1:30000000-30000000"; if ( regidx_insert(idx,line)!=0 ) error("insert failed: %s\n", line); + + // Test + regitr_t *itr = regitr_init(idx); + int from, to; + + from = to = 10000000; + if ( !regidx_overlap(idx,"1",from-1,to-1,itr) ) error("query failed: 1:%d-%d\n",from,to); + if ( strcmp("1:10000000-10000000",regitr_payload(itr,char*)) ) error("query failed: 1:%d-%d vs %s\n", from,to,regitr_payload(itr,char*)); + if ( !regidx_overlap(idx,"1",from-2,to-1,itr) ) error("query failed: 1:%d-%d\n",from-1,to); + if ( !regidx_overlap(idx,"1",from-2,to+3,itr) ) error("query failed: 1:%d-%d\n",from-1,to+2); + if ( regidx_overlap(idx,"1",from-2,to-2,itr) ) error("query failed: 1:%d-%d\n",from-1,to-1); + + from = to = 20000000; + if ( !regidx_overlap(idx,"1",from-1,to-1,itr) ) error("query failed: 1:%d-%d\n",from,to); + + from = to = 20000002; + if ( !regidx_overlap(idx,"1",from-1,to-1,itr) ) error("query failed: 1:%d-%d\n",from,to); + + from = to = 30000000; + if ( !regidx_overlap(idx,"1",from-1,to-1,itr) ) error("query failed: 1:%d-%d\n",from,to); + + // Clean up + regitr_destroy(itr); + regidx_destroy(idx); +} + +void get_random_region(uint32_t min, uint32_t max, uint32_t *beg, uint32_t *end) +{ + long int b = random(), e = random(); + *beg = min + (float)b * (max-min) / RAND_MAX; + *end = *beg + (float)e * (max-*beg) / RAND_MAX; +} + +void test_random(int nregs, uint32_t min, uint32_t max) +{ + min--; + max--; + + // Init index with no file name, we will insert the regions manually + regidx_t *idx = regidx_init(NULL,custom_parse,custom_free,sizeof(char*),NULL); + if ( !idx ) error("init failed\n"); + + // Test region + uint32_t beg,end; + get_random_region(min,max,&beg,&end); + + // Insert regions + int i, nexp = 0; + kstring_t str = {0,0,0}; + for (i=0; i=beg && b<=end ) nexp++; + } + + // Test + regitr_t *itr = regitr_init(idx); + int nhit = 0, ret = regidx_overlap(idx,"1",beg,end,itr); + if ( nexp && !ret ) error("query failed, expected %d overlap(s), found none: %d-%d\n", nexp,beg+1,end+1); + if ( !nexp && ret ) error("query failed, expected no overlaps, found some: %d-%d\n", beg+1,end+1); + while ( ret && regitr_overlap(itr) ) + { + str.l = 0; + ksprintf(&str,"1:%"PRIu32"-%"PRIu32"",itr->beg+1,itr->end+1); + if ( strcmp(str.s,regitr_payload(itr,char*)) ) + error("query failed, incorrect payload: %s vs %s (%d-%d)\n",str.s,regitr_payload(itr,char*),beg+1,end+1); + if ( itr->beg > end || itr->end < beg ) + error("query failed, incorrect hit: %d-%d vs %d-%d, payload %s\n", beg+1,end+1,itr->beg+1,itr->end+1,regitr_payload(itr,char*)); + nhit++; + } + if ( nexp!=nhit ) error("query failed, expected %d overlap(s), found %d: %d-%d\n",nexp,nhit,beg+1,end+1); + debug("ok: found %d overlaps\n", nexp); + + // Clean up + regitr_destroy(itr); + regidx_destroy(idx); + free(str.s); +} + +void create_line_bed(char *line, char *chr, int start, int end) +{ + sprintf(line,"%s\t%d\t%d\n",chr,start-1,end); +} +void create_line_tab(char *line, char *chr, int start, int end) +{ + sprintf(line,"%s\t%d\t%d\n",chr,start,end); +} +void create_line_reg(char *line, char *chr, int start, int end) +{ + sprintf(line,"%s:%d-%d\n",chr,start,end); +} + +typedef void (*set_line_f)(char *line, char *chr, int start, int end); + +void test(set_line_f set_line, regidx_parse_f parse) +{ + regidx_t *idx = regidx_init(NULL,parse,NULL,0,NULL); + if ( !idx ) error("init failed\n"); + + char line[250], *chr = "1"; + int i, n = 10, start, end, nhit; + for (i=1; ibeg > end-1 || itr->end < start-1 ) error("query failed, incorrect region: %d-%d for %d-%d\n",itr->beg+1,itr->end+1,start,end); + debug("\t %d-%d\n",itr->beg+1,itr->end+1); + nhit++; + } + if ( nhit!=1 ) error("query failed, expected one hit, found %d: %s:%d-%d\n",nhit,chr,start,end); + + + // one hit + start = end = 10*i+1; + if ( !regidx_overlap(idx,chr,start-1,end-1,itr) ) error("query failed, there should be a hit: %s:%d-%d\n",chr,start,end); + debug("ok: overlap(s) found for %s:%d-%d\n",chr,start,end); + nhit = 0; + while ( regitr_overlap(itr) ) + { + if ( itr->beg > end-1 || itr->end < start-1 ) error("query failed, incorrect region: %d-%d for %d-%d\n",itr->beg+1,itr->end+1,start,end); + debug("\t %d-%d\n",itr->beg+1,itr->end+1); + nhit++; + } + if ( nhit!=1 ) error("query failed, expected one hit, found %d: %s:%d-%d\n",nhit,chr,start,end); + + + // two hits + start = 10*i; end = start+1; + if ( !regidx_overlap(idx,chr,start-1,end-1,itr) ) error("query failed, there should be a hit: %s:%d-%d\n",chr,start,end); + debug("ok: overlap(s) found for %s:%d-%d\n",chr,start,end); + nhit = 0; + while ( regitr_overlap(itr) ) + { + if ( itr->beg > end-1 || itr->end < start-1 ) error("query failed, incorrect region: %d-%d for %d-%d\n",itr->beg+1,itr->end+1,start,end); + debug("\t %d-%d\n",itr->beg+1,itr->end+1); + nhit++; + } + if ( nhit!=2 ) error("query failed, expected two hits, found %d: %s:%d-%d\n",nhit,chr,start,end); + + } + regitr_destroy(itr); + regidx_destroy(idx); +} + +static void usage(void) +{ + fprintf(stderr, "Usage: test-regidx [OPTIONS]\n"); + fprintf(stderr, "Options:\n"); + fprintf(stderr, " -h, --help this help message\n"); + fprintf(stderr, " -s, --seed random seed\n"); + fprintf(stderr, " -v, --verbose increase verbosity by giving multiple times\n"); + + exit(1); +} + +int main(int argc, char **argv) +{ + static struct option loptions[] = + { + {"help",0,0,'h'}, + {"verbose",0,0,'v'}, + {"seed",1,0,'s'}, + {0,0,0,0} + }; + char c; + int seed = (int)time(NULL); + while ((c = getopt_long(argc, argv, "hvs:",loptions,NULL)) >= 0) + { + switch (c) + { + case 's': seed = atoi(optarg); break; + case 'v': verbose++; break; + default: usage(); break; + } + } + + info("Testing sequential access\n"); + test_sequential_access(); + + info("Testing TAB\n"); + test(create_line_tab,regidx_parse_tab); + + info("Testing REG\n"); + test(create_line_reg,regidx_parse_reg); + + info("Testing BED\n"); + test(create_line_bed,regidx_parse_bed); + + info("Testing custom payload\n"); + test_custom_payload(); + + int i, ntest = 1000, nreg = 50; + srandom(seed); + info("%d randomized tests, %d regions per test. Random seed is %d\n", ntest,nreg,seed); + for (i=0; i +# +# Permission is hereby granted, free of charge, to any person obtaining a copy +# of this software and associated documentation files (the "Software"), to deal +# in the Software without restriction, including without limitation the rights +# to use, copy, modify, merge, publish, distribute, sublicense, and/or sell +# copies of the Software, and to permit persons to whom the Software is +# furnished to do so, subject to the following conditions: +# +# The above copyright notice and this permission notice shall be included in +# all copies or substantial portions of the Software. +# +# THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +# IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +# FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL +# THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER +# LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING +# FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER +# DEALINGS IN THE SOFTWARE. + +use strict; +use warnings; +use Carp; +#use IPC::Open2; +use FindBin; +use lib "$FindBin::Bin"; +use Getopt::Long; +use File::Temp qw/ tempfile tempdir /; +use Cwd qw/ abs_path /; + +my $opts = parse_params(); +test_usage($opts,cmd=>'bcftools'); +test_tabix($opts,in=>'merge.a',reg=>'2:3199812-3199812',out=>'tabix.2.3199812.out'); +test_tabix($opts,in=>'merge.a',reg=>'1:3000151-3000151',out=>'tabix.1.3000151.out'); +test_index($opts,in=>'large_chrom_csi_limit',reg=>'chr20:1-2147483647',out=>'large_chrom_csi_limit.20.1.2147483647.out'); # 2147483647 (1<<31-1) is the current chrom limit for csi. bcf conversion and indexing fail above this +test_index($opts,in=>'large_chrom_csi_limit',reg=>'chr20',out=>'large_chrom.20.1.2147483647.out'); # this fails until bug resolved +test_vcf_idxstats($opts,in=>'idx',args=>'-s',out=>'idx.out'); +test_vcf_idxstats($opts,in=>'idx',args=>'-n',out=>'idx_count.out'); +test_vcf_idxstats($opts,in=>'empty',args=>'-s',out=>'empty.idx.out'); +test_vcf_idxstats($opts,in=>'empty',args=>'-n',out=>'empty.idx_count.out'); +test_vcf_check($opts,in=>'check',out=>'check.chk'); +test_vcf_check_merge($opts,in=>'check',out=>'check_merge.chk'); +test_vcf_stats($opts,in=>['stats.a','stats.b'],out=>'stats.chk',args=>'-s -'); +test_vcf_stats($opts,in=>['stats.a','stats.b'],out=>'stats.B.chk',args=>'-s B'); +test_vcf_isec($opts,in=>['isec.a','isec.b'],out=>'isec.ab.out',args=>'-n =2'); +test_vcf_isec($opts,in=>['isec.a','isec.b'],out=>'isec.ab.flt.out',args=>'-n =2 -i"STRLEN(REF)==2"'); +test_vcf_isec($opts,in=>['isec.a','isec.b'],out=>'isec.ab.both.out',args=>'-n =2 -c both'); +test_vcf_isec($opts,in=>['isec.a','isec.b'],out=>'isec.ab.any.out',args=>'-n =2 -c any'); +test_vcf_isec($opts,in=>['isec.a','isec.b'],out=>'isec.ab.C.out',args=>'-C -c any'); +test_vcf_isec2($opts,vcf_in=>['isec.a'],tab_in=>'isec',out=>'isec.tab.out',args=>''); +test_vcf_merge($opts,in=>['merge.a','merge.b','merge.c'],out=>'merge.abc.out',args=>'--force-samples'); +test_vcf_merge($opts,in=>['merge.a','merge.b','merge.c'],out=>'merge.abc.2.out',args=>'--force-samples -Fx'); +test_vcf_merge($opts,in=>['merge.a','merge.b','merge.c'],out=>'merge.abc.3.out',args=>'--force-samples -0'); +test_vcf_merge($opts,in=>['merge.2.a','merge.2.b'],out=>'merge.2.none.out',args=>'--force-samples -m none'); +test_vcf_merge($opts,in=>['merge.2.a','merge.2.b'],out=>'merge.2.both.out',args=>'--force-samples -m both'); +test_vcf_merge($opts,in=>['merge.2.a','merge.2.b'],out=>'merge.2.all.out',args=>'--force-samples -m all'); +test_vcf_merge($opts,in=>['merge.3.a','merge.3.b'],out=>'merge.3.out',args=>'--force-samples -i TR:sum,TA:sum,TG:sum'); +test_vcf_merge($opts,in=>['merge.4.a','merge.4.b'],out=>'merge.4.out',args=>'--force-samples -m id'); +test_vcf_merge($opts,in=>['gvcf.merge.1','gvcf.merge.2','gvcf.merge.3'],out=>'gvcf.merge.1.out',args=>'--gvcf -'); +test_vcf_merge($opts,in=>['merge.gvcf.2.a','merge.gvcf.2.b','merge.gvcf.2.c'],out=>'merge.gvcf.2.out',args=>'--gvcf -'); +test_vcf_merge($opts,in=>['merge.5.a','merge.5.b'],out=>'merge.5.out'); +test_vcf_query($opts,in=>'query',out=>'query.out',args=>q[-f '%CHROM\\t%POS\\t%REF\\t%ALT\\t%DP4\\t%AN[\\t%GT\\t%TGT]\\n']); +test_vcf_query($opts,in=>'view.filter',out=>'query.2.out',args=>q[-f'%XRI\\n' -i'XRI[*]>1111']); +test_vcf_query($opts,in=>'view.filter',out=>'query.3.out',args=>q[-f'%XRF\\n' -i'XRF[*]=2e6']); +test_vcf_query($opts,in=>'view.filter',out=>'query.4.out',args=>q[-f'%XGS\\n' -i'XGS[5]="PQR"']); +test_vcf_query($opts,in=>'view.filter',out=>'query.4.out',args=>q[-f'%XGS\\n' -i'XGS[*]="GHI"']); +test_vcf_query($opts,in=>'view.filter',out=>'query.4.out',args=>q[-f'%XGS\\n' -i'XGS[2]~"H"']); +test_vcf_query($opts,in=>'view.filter',out=>'query.4.out',args=>q[-f'%XGS\\n' -i'XGS[3]!~"H"']); +test_vcf_query($opts,in=>'view.filter',out=>'query.4.out',args=>q[-f'%XGS\\n' -i'XGS[*]~"H"']); +test_vcf_query($opts,in=>'view.filter',out=>'query.4.out',args=>q[-f'%XGS\\n' -i'XGS[*]~"HI,JK"']); +test_vcf_query($opts,in=>'query',out=>'query.5.out',args=>q[-f'%POS %REF %ALT\\n' -i'REF~"C" && ALT~"CT"']); +test_vcf_query($opts,in=>'query',out=>'query.6.out',args=>q[-f'%POS %REF %ALT\\n' -i'N_ALT=2']); +test_vcf_query($opts,in=>'query',out=>'query.7.out',args=>q[-f'%POS %AN\\n' -i'AN!=2*N_SAMPLES']); +test_vcf_query($opts,in=>'query',out=>'query.8.out',args=>q[-f'%POS[ %GL]\\n' -i'min(abs(GL[0]))=10']); +test_vcf_query($opts,in=>'view.filter',out=>'query.9.out',args=>q[-f'%POS %CIGAR\\n' -i'strlen(CIGAR[*])=4']); +test_vcf_query($opts,in=>'query',out=>'query.10.out',args=>q[-f'%POS[ %GT]\\n' -i'AC[0]=3']); +test_vcf_query($opts,in=>'query',out=>'query.10.out',args=>q[-f'%POS[ %GT]\\n' -i'AF[0]=3/4']); +test_vcf_query($opts,in=>'query',out=>'query.11.out',args=>q[-f'%POS[ %GT]\\n' -i'MAC[0]=1']); +test_vcf_query($opts,in=>'query',out=>'query.11.out',args=>q[-f'%POS[ %GT]\\n' -i'MAF[0]=1/4']); +test_vcf_query($opts,in=>'view.vectors',out=>'query.12.out',args=>q[-f'I8=%I8 I16=%I16 I32=%I32 IF=%IF IA8=%IA8 IA16=%IA16 IA32=%IA32 IAF=%IAF IA8=%IA8{1} IA16=%IA16{1} IA32=%IA32{1} IAF=%IAF{1} [ %F8:%F16:%F32:%FF]\\n']); +test_vcf_query($opts,in=>'query.filter',out=>'query.13.out',args=>q[-f'%POS[ %GT]\\n' -i'GT ="1"']); +test_vcf_query($opts,in=>'query.filter',out=>'query.14.out',args=>q[-f'%POS[ %GT]\\n' -i'GT!="1"']); +test_vcf_query($opts,in=>'query.filter',out=>'query.15.out',args=>q[-f'%POS[ %GT]\\n' -e'GT ="1"']); +test_vcf_query($opts,in=>'query.filter',out=>'query.16.out',args=>q[-f'%POS[ %GT]\\n' -e'GT!="1"']); +test_vcf_query($opts,in=>'query.2',out=>'query.17.out',args=>q[-f'%XX_A %XX.A %XX.A0 %xx.a0\\n']); +test_vcf_query($opts,in=>'missing',out=>'query.18.out',args=>q[-i'IINT="."' -f'%POS %IINT\\n']); +test_vcf_query($opts,in=>'missing',out=>'query.19.out',args=>q[-i'IINT!="."' -f'%POS %IINT\\n']); +test_vcf_query($opts,in=>'missing',out=>'query.18.out',args=>q[-e'IINT!="."' -f'%POS %IINT\\n']); +test_vcf_query($opts,in=>'missing',out=>'query.19.out',args=>q[-e'IINT="."' -f'%POS %IINT\\n']); +test_vcf_query($opts,in=>'missing',out=>'query.20.out',args=>q[-i'IFLT="."' -f'%POS %IFLT\\n']); +test_vcf_query($opts,in=>'missing',out=>'query.21.out',args=>q[-i'IFLT!="."' -f'%POS %IFLT\\n']); +test_vcf_query($opts,in=>'missing',out=>'query.20.out',args=>q[-e'IFLT!="."' -f'%POS %IFLT\\n']); +test_vcf_query($opts,in=>'missing',out=>'query.21.out',args=>q[-e'IFLT="."' -f'%POS %IFLT\\n']); +test_vcf_query($opts,in=>'missing',out=>'query.22.out',args=>q[-i'ISTR="."' -f'%POS %ISTR\\n']); +test_vcf_query($opts,in=>'missing',out=>'query.23.out',args=>q[-i'ISTR!="."' -f'%POS %ISTR\\n']); +test_vcf_query($opts,in=>'missing',out=>'query.23.out',args=>q[-e'ISTR="."' -f'%POS %ISTR\\n']); +test_vcf_query($opts,in=>'missing',out=>'query.22.out',args=>q[-e'ISTR!="."' -f'%POS %ISTR\\n']); +test_vcf_query($opts,in=>'missing',out=>'query.24.out',args=>q[-i'FILTER="q11"' -f'%POS %ISTR\\n']); +test_vcf_query($opts,in=>'query',out=>'query.25.out',args=>q[-f'%LINE']); +test_vcf_query($opts,in=>'query.filter-type',out=>'query.26.out',args=>q[-f'%POS\\t%REF\\t%ALT\\n' -i'type="snp"']); +test_vcf_query($opts,in=>'query.filter-type',out=>'query.27.out',args=>q[-f'%POS\\t%REF\\t%ALT\\n' -i'type~"snp"']); +test_vcf_query($opts,in=>'query.filter-type',out=>'query.28.out',args=>q[-f'%POS\\t%REF\\t%ALT\\n' -i'type!="snp"']); +test_vcf_query($opts,in=>'query.filter-type',out=>'query.29.out',args=>q[-f'%POS\\t%REF\\t%ALT\\n' -i'type!~"snp"']); +test_vcf_query($opts,in=>'filter-missing-floats',out=>'query.30.out',args=>q[-f'%POS\\t%A_AF\\t%B_AF\\t%C_AF\\n' -i'A_AF>=0.0001 || B_AF >= 0.0001 || C_AF >= 0.0001']); +test_vcf_query($opts,in=>'filter-missing-floats',out=>'query.31.out',args=>q[-f'%POS\\t%A_AF\\t%B_AF\\t%C_AF\\n' -e'A_AF>=0.0001 || B_AF >= 0.0001 || C_AF >= 0.0001']); +test_vcf_query($opts,in=>'missing',out=>'query.32.out',args=>q[-i'FMT/FINT!="."' -f'[\t%FINT]\\n']); +test_vcf_query($opts,in=>'query.filter.2',out=>'query.33.out',args=>q[-f'[%GT]\\n' -i'GT~"0/[1-9]" || GT~"[1-9]/0"']); +test_vcf_norm($opts,in=>'norm',out=>'norm.out',fai=>'norm',args=>'-cx'); +test_vcf_norm($opts,in=>'norm.split',out=>'norm.split.out',args=>'-m-'); +test_vcf_norm($opts,in=>'norm.split.2',out=>'norm.split.2.out',args=>'-m-'); +test_vcf_norm($opts,in=>'norm.split',fai=>'norm',out=>'norm.split.and.norm.out',args=>'-m-'); +test_vcf_norm($opts,in=>'norm.merge',out=>'norm.merge.out',args=>'-m+'); +test_vcf_norm($opts,in=>'norm.merge.2',out=>'norm.merge.2.out',args=>'-m+'); +test_vcf_norm($opts,in=>'norm.merge.3',out=>'norm.merge.3.out',args=>'-m+'); +test_vcf_norm($opts,in=>'norm.merge',out=>'norm.merge.strict.out',args=>'-m+ -s'); +test_vcf_norm($opts,in=>'norm.setref',out=>'norm.setref.out',args=>'-Nc s',fai=>'norm'); +test_vcf_norm($opts,in=>'norm.telomere',out=>'norm.telomere.out',fai=>'norm'); +test_vcf_view($opts,in=>'view',out=>'view.1.out',args=>'-aUc1 -C1 -s NA00002 -v snps',reg=>''); +test_vcf_view($opts,in=>'view',out=>'view.2.out',args=>'-f PASS -Xks NA00003',reg=>'-r20,Y'); +test_vcf_view($opts,in=>'view',out=>'view.3.out',args=>'-xs NA00003',reg=>''); +test_vcf_view($opts,in=>'view',out=>'view.4.out',args=>q[-i 'QUAL==999 && (FS<20 || FS>=41.02) && ICF>-0.1 && HWE*2>1.2'],reg=>''); +test_vcf_view($opts,in=>'view',out=>'view.5.out',args=>q[-p],reg=>''); +test_vcf_view($opts,in=>'view',out=>'view.6.out',args=>q[-P],reg=>''); +test_vcf_view($opts,in=>'view',out=>'view.7.out',args=>q[-hm2 -M2 -q0.3 -Q0.7],reg=>''); +test_vcf_view($opts,in=>'view',out=>'view.8.out',args=>q[-Hu],reg=>''); +test_vcf_view($opts,in=>'view',out=>'view.9.out',args=>q[-GVsnps],reg=>''); +test_vcf_view($opts,in=>'view',out=>'view.10.out',args=>q[-ne 'INDEL=1 || PV4[0]<0.006'],reg=>''); +test_vcf_view($opts,in=>'view',out=>'view.exclude.out',args=>'-s ^NA00003',reg=>''); +test_vcf_view($opts,in=>'view.omitgenotypes',out=>'view.omitgenotypes.out',args=>'',reg=>''); +test_vcf_view($opts,in=>'view.omitgenotypes',out=>'view.dropgenotypes.out',args=>'-G',reg=>''); +test_vcf_view($opts,in=>'view.omitgenotypes',out=>'view.dropgenotypes.noheader.out',args=>'-HG',reg=>''); +test_vcf_view($opts,in=>'many.alleles',out=>'many.alleles.trim.out',args=>'-a',reg=>''); +test_vcf_view($opts,in=>'view.vectors',out=>'view.vectors.A.out',args=>'-asA',reg=>''); +test_vcf_view($opts,in=>'view.vectors',out=>'view.vectors.B.out',args=>'-asB',reg=>''); +test_vcf_view($opts,in=>'view.vectors.2',out=>'view.vectors.C.out',args=>'-asA',reg=>''); +test_vcf_view($opts,in=>'view.filter',out=>'view.filter.1.out',args=>q[-H -i'FMT/FGS[0]="AAAAAA"'],reg=>''); # test expressions +test_vcf_view($opts,in=>'view.filter',out=>'view.filter.2.out',args=>q[-H -i'FMT/FGS[2]="C"'],reg=>''); +test_vcf_view($opts,in=>'view.filter',out=>'view.filter.3.out',args=>q[-H -i'FMT/FGS[4]="EE"'],reg=>''); +test_vcf_view($opts,in=>'view.filter',out=>'view.filter.4.out',args=>q[-H -i'FMT/FRS[1]="BB"'],reg=>''); +test_vcf_view($opts,in=>'view.filter',out=>'view.filter.5.out',args=>q[-H -i'TXT0="text"'],reg=>''); +test_vcf_view($opts,in=>'view.chrs',out=>'view.chrs.out',args=>'',reg=>'',tgts=>'view.chrs.tab'); +test_vcf_view($opts,in=>'filter.2',out=>'filter.11.out',args=>q[-i 'POS>=3062917'],reg=>'1:3062917-3157410'); +test_vcf_filter($opts,in=>'view.filter',out=>'view.filter.6.out',args=>q[-S. -e'TXT0="text"'],reg=>''); +test_vcf_filter($opts,in=>'view.filter',out=>'view.filter.7.out',args=>q[-S. -e'FMT/FRS[1]="BB"'],reg=>''); +test_vcf_filter($opts,in=>'view.filter',out=>'view.filter.8.out',args=>q[-S. -e'FMT/FGS[0]="AAAAAA"'],reg=>''); +test_vcf_filter($opts,in=>'view.filter',out=>'view.filter.9.out',args=>q[-S. -e'FMT/FGS[1]="BBB"'],reg=>''); +test_vcf_filter($opts,in=>'view.filter',out=>'view.filter.10.out',args=>q[-S. -e'FMT/FGS[4]="EE"'],reg=>''); +test_vcf_filter($opts,in=>'view.filter',out=>'view.filter.11.out',args=>q[-S. -e'FMT/STR="XX"'],reg=>''); +test_vcf_view($opts,in=>'view.minmaxac',out=>'view.minmaxac.1.out',args=>q[-H -C5:nonmajor],reg=>''); +test_vcf_view($opts,in=>'view.minmaxac',out=>'view.minmaxac.2.out',args=>q[-H -c6:nonmajor],reg=>''); +test_vcf_view($opts,in=>'view.minmaxac',out=>'view.minmaxac.1.out',args=>q[-H -q0.3:major],reg=>''); +test_vcf_view($opts,in=>'view.filter.annovar',out=>'view.filter.annovar.1.out',args=>q[-H -i 'Gene.refGene=="RAD21L1"'],reg=>''); +test_vcf_view($opts,in=>'view.filter.annovar',out=>'view.filter.annovar.2.out',args=>q[-H -i 'Gene.refGene~"NOD"'],reg=>''); +test_vcf_view($opts,in=>'view.filter.annovar',out=>'view.filter.annovar.3.out',args=>q[-H -i 'LJB2_MutationTaster=="0.291000"'],reg=>''); +test_vcf_call($opts,in=>'mpileup',out=>'mpileup.1.out',args=>'-mv'); +test_vcf_call($opts,in=>'mpileup',out=>'mpileup.2.out',args=>'-mg0'); +test_vcf_call($opts,in=>'mpileup.X',out=>'mpileup.X.out',args=>'-mv --ploidy-file {PATH}/mpileup.ploidy -S {PATH}/mpileup.samples'); +test_vcf_call($opts,in=>'mpileup.X',out=>'mpileup.X.out',args=>'-mv --ploidy-file {PATH}/mpileup.ploidy -S {PATH}/mpileup.ped'); +test_vcf_call($opts,in=>'mpileup.X',out=>'mpileup.X.2.out',args=>'-mv --ploidy-file {PATH}/mpileup.ploidy -S {PATH}/mpileup.2.samples'); +test_vcf_call_cAls($opts,in=>'mpileup',out=>'mpileup.cAls.out',tab=>'mpileup'); +test_vcf_call($opts,in=>'mpileup.c',out=>'mpileup.c.1.out',args=>'-cv'); +# test_vcf_call($opts,in=>'mpileup.c',out=>'mpileup.c.2.out',args=>'-cg0'); +test_vcf_call($opts,in=>'mpileup.c.X',out=>'mpileup.c.X.out',args=>'-cv --ploidy-file {PATH}/mpileup.ploidy -S {PATH}/mpileup.samples'); +test_vcf_call($opts,in=>'mpileup.c.X',out=>'mpileup.c.X.out',args=>'-cv --ploidy-file {PATH}/mpileup.ploidy -S {PATH}/mpileup.ped'); +test_vcf_call($opts,in=>'mpileup.c.X',out=>'mpileup.c.X.2.out',args=>'-cv --ploidy-file {PATH}/mpileup.ploidy -S {PATH}/mpileup.2.samples'); +test_vcf_filter($opts,in=>'filter.1',out=>'filter.1.out',args=>'-mx -g2 -G2'); +test_vcf_filter($opts,in=>'filter.2',out=>'filter.2.out',args=>q[-e'QUAL==59.2 || (INDEL=0 & (FMT/GQ=25 | FMT/DP=10))' -sModified -S.]); +test_vcf_filter($opts,in=>'filter.3',out=>'filter.3.out',args=>q[-e'DP=19'],fmt=>'%POS\\t%FILTER\\t%DP[\\t%GT]\\n'); +test_vcf_filter($opts,in=>'filter.3',out=>'filter.4.out',args=>q[-e'DP=19' -s XX],fmt=>'%POS\\t%FILTER\\t%DP[\\t%GT]\\n'); +test_vcf_filter($opts,in=>'filter.3',out=>'filter.5.out',args=>q[-e'DP=19' -s XX -m+],fmt=>'%POS\\t%FILTER\\t%DP[\\t%GT]\\n'); +test_vcf_filter($opts,in=>'filter.3',out=>'filter.6.out',args=>q[-e'DP=19' -s XX -mx],fmt=>'%POS\\t%FILTER\\t%DP[\\t%GT]\\n'); +test_vcf_filter($opts,in=>'filter.3',out=>'filter.7.out',args=>q[-e'DP=19' -s XX -m+x],fmt=>'%POS\\t%FILTER\\t%DP[\\t%GT]\\n'); +test_vcf_filter($opts,in=>'filter.3',out=>'filter.3.out',args=>q[-e'FMT/GT="0/2"'],fmt=>'%POS\\t%FILTER\\t%DP[\\t%GT]\\n'); +test_vcf_filter($opts,in=>'filter.3',out=>'filter.4.out',args=>q[-e'FMT/GT="0/2"' -s XX],fmt=>'%POS\\t%FILTER\\t%DP[\\t%GT]\\n'); +test_vcf_filter($opts,in=>'filter.3',out=>'filter.5.out',args=>q[-e'FMT/GT="0/2"' -s XX -m+],fmt=>'%POS\\t%FILTER\\t%DP[\\t%GT]\\n'); +test_vcf_filter($opts,in=>'filter.3',out=>'filter.6.out',args=>q[-e'FMT/GT="0/2"' -s XX -mx],fmt=>'%POS\\t%FILTER\\t%DP[\\t%GT]\\n'); +test_vcf_filter($opts,in=>'filter.3',out=>'filter.7.out',args=>q[-e'FMT/GT="0/2"' -s XX -m+x],fmt=>'%POS\\t%FILTER\\t%DP[\\t%GT]\\n'); +test_vcf_filter($opts,in=>'filter.2',out=>'filter.8.out',args=>q[-i'FMT/GT="0/0" && AC[*]=2'],fmt=>'%POS\\t%AC[\\t%GT]\\n'); +test_vcf_filter($opts,in=>'filter.2',out=>'filter.8.out',args=>q[-i'AC[*]=2 && FMT/GT="0/0"'],fmt=>'%POS\\t%AC[\\t%GT]\\n'); +test_vcf_filter($opts,in=>'filter.2',out=>'filter.9.out',args=>q[-i'ALT="."'],fmt=>'%POS\\t%AC[\\t%GT]\\n'); +test_vcf_filter($opts,in=>'filter.4',out=>'filter.10.out',args=>q[-S . -i 'FORMAT/TEST3<25']); +test_vcf_filter($opts,in=>'filter.4',out=>'filter.10.out',args=>q[-S . -i 'FORMAT/TEST4<25']); +test_vcf_regions($opts,in=>'regions'); +test_vcf_annotate($opts,in=>'annotate',tab=>'annotate',out=>'annotate.out',args=>'-c CHROM,POS,REF,ALT,ID,QUAL,INFO/T_INT,INFO/T_FLOAT,INDEL'); +test_vcf_annotate($opts,in=>'annotate',tab=>'annotate2',out=>'annotate2.out',args=>'-c CHROM,FROM,TO,T_STR'); +test_vcf_annotate($opts,in=>'annotate',vcf=>'annots',out=>'annotate3.out',args=>'-c STR,ID,QUAL,FILTER'); +test_vcf_annotate($opts,in=>'annotate2',vcf=>'annots2',out=>'annotate4.out',args=>'-c ID,QUAL,FILTER,INFO,FMT'); +test_vcf_annotate($opts,in=>'annotate2',vcf=>'annots2',out=>'annotate5.out',args=>'-c ID,QUAL,+FILTER,+INFO,FMT/GT -s A'); +test_vcf_annotate($opts,in=>'annotate3',out=>'annotate6.out',args=>'-x ID,QUAL,^FILTER/fltA,FILTER/fltB,^INFO/AA,INFO/BB,^FMT/GT,FMT/PL'); +test_vcf_annotate($opts,in=>'annotate3',out=>'annotate7.out',args=>'-x FORMAT'); +test_vcf_annotate($opts,in=>'annotate4',vcf=>'annots4',out=>'annotate8.out',args=>'-c +INFO'); +test_vcf_annotate($opts,in=>'annotate4',tab=>'annots4',out=>'annotate8.out',args=>'-c CHROM,POS,REF,ALT,+FA,+FR,+IA,+IR,+SA,+SR'); +test_vcf_annotate($opts,in=>'annotate10',tab=>'annots10',out=>'annotate10.out',args=>'-c CHROM,POS,FMT/FINT,FMT/FFLT,FMT/FSTR'); +test_vcf_annotate($opts,in=>'annotate2',vcf=>'annots2',out=>'annotate11.out',args=>'-c CHROM,POS,FMT/FINT,FMT/FFLT,FMT/FSTR -s A'); +test_vcf_annotate($opts,in=>'annotate2',tab=>'annots11',out=>'annotate11.out',args=>'-c CHROM,POS,FMT/FINT,FMT/FFLT,FMT/FSTR -s A'); +test_vcf_annotate($opts,in=>'annotate2',vcf=>'annots2',out=>'annotate12.out',args=>'-c AAA:=IINT,FMT/BBB:=FMT/FINT'); +test_vcf_annotate($opts,in=>'annotate2',vcf=>'annots2',out=>'annotate13.out',args=>'-x INFO -c INFO/IINT'); +test_vcf_plugin($opts,in=>'plugin1',out=>'missing2ref.out',cmd=>'+missing2ref --no-version'); +test_vcf_plugin($opts,in=>'plugin1',out=>'missing2ref.out',cmd=>'+setGT --no-version',args=>'-- -t . -n 0'); +test_vcf_plugin($opts,in=>'setGT',out=>'setGT.1.out',cmd=>'+setGT --no-version',args=>'-- -t q -n 0 -i \'GT~"." && FMT/DP=30 && GQ=150\''); +test_vcf_annotate($opts,in=>'annotate9',tab=>'annots9',out=>'annotate9.out',args=>'-c CHROM,POS,REF,ALT,+ID'); +test_vcf_plugin($opts,in=>'plugin1',out=>'fill-AN-AC.out',cmd=>'+fill-AN-AC --no-version'); +test_vcf_plugin($opts,in=>'plugin1',out=>'dosage.out',cmd=>'+dosage'); +test_vcf_plugin($opts,in=>'fixploidy',out=>'fixploidy.out',cmd=>'+fixploidy --no-version',args=>'-- -s {PATH}/fixploidy.samples -p {PATH}/fixploidy.ploidy'); +test_vcf_plugin($opts,in=>'view.PL',out=>'guess-ploidy.PL.out',cmd=>'+guess-ploidy',args=>'-vrX | grep -v bcftools'); +test_vcf_plugin($opts,in=>'view.GL',out=>'guess-ploidy.GL.out',cmd=>'+guess-ploidy',args=>'-vrX | grep -v bcftools'); +test_vcf_plugin($opts,in=>'view.GL',out=>'view.PL.vcf',cmd=>'+tag2tag --no-version',args=>'-- -r --gl-to-pl'); +test_vcf_plugin($opts,in=>'view.GP',out=>'view.GT.vcf',cmd=>'+tag2tag --no-version',args=>'-- -r --gp-to-gt -t 0.2'); +test_vcf_plugin($opts,in=>'merge.a',out=>'fill-tags.out',cmd=>'+fill-tags --no-version',args=>'-- -t AN,AC,AC_Hom,AC_Het,AC_Hemi'); +test_vcf_plugin($opts,in=>'view',out=>'fill-tags.2.out',cmd=>'+fill-tags --no-version',args=>'-- -t AC,AN,AF,MAF,NS'); +test_vcf_plugin($opts,in=>'view',out=>'fill-tags.3.out',cmd=>'+fill-tags --no-version',args=>'-- -t AC -S {PATH}/fill-tags.3.smpl'); +test_vcf_plugin($opts,in=>'fill-tags-hemi',out=>'fill-tags-hemi.1.out',cmd=>'+fill-tags --no-version'); +test_vcf_plugin($opts,in=>'fill-tags-hemi',out=>'fill-tags-hemi.2.out',cmd=>'+fill-tags --no-version',args=>'-- -d'); +test_vcf_plugin($opts,in=>'view',out=>'view.GTisec.out',cmd=>'+GTisec',args=>' | grep -v bcftools'); +test_vcf_plugin($opts,in=>'view',out=>'view.GTisec.H.out',cmd=>'+GTisec',args=>'-- -H | grep -v bcftools'); +test_vcf_plugin($opts,in=>'view',out=>'view.GTisec.Hm.out',cmd=>'+GTisec',args=>'-- -Hm | grep -v bcftools'); +test_vcf_plugin($opts,in=>'view',out=>'view.GTisec.Hmv.out',cmd=>'+GTisec',args=>'-- -Hmv | grep -v bcftools'); +test_vcf_plugin($opts,in=>'view',out=>'view.GTisec.Hv.out',cmd=>'+GTisec',args=>'-- -Hv | grep -v bcftools'); +test_vcf_plugin($opts,in=>'view',out=>'view.GTisec.m.out',cmd=>'+GTisec',args=>'-- -m | grep -v bcftools'); +test_vcf_plugin($opts,in=>'view',out=>'view.GTisec.mv.out',cmd=>'+GTisec',args=>'-- -mv | grep -v bcftools'); +test_vcf_plugin($opts,in=>'view',out=>'view.GTisec.v.out',cmd=>'+GTisec',args=>'-- -v | grep -v bcftools'); +test_vcf_plugin($opts,in=>'trio',out=>'trio.out',cmd=>'+trio-switch-rate',args=>'-- -p {PATH}/trio.ped | grep -v bcftools'); +test_vcf_plugin($opts,in=>'ad-bias',out=>'ad-bias.out',cmd=>'+ad-bias',args=>'-- -s {PATH}/ad-bias.samples | grep -v bcftools'); +test_vcf_plugin($opts,in=>'af-dist',out=>'af-dist.out',cmd=>'+af-dist',args=>' | grep -v bcftools'); +test_vcf_plugin($opts,in=>'fixref',out=>'fixref.1.out',cmd=>'+fixref',args=>'-- -f {PATH}/norm.fa -m top'); +test_vcf_plugin($opts,in=>'aa',out=>'aa.out',cmd=>'+fill-from-fasta',args=>'-- -f {PATH}/aa.fa -c AA -h {PATH}/aa.hdr -i \'TYPE="snp"\''); +test_vcf_plugin($opts,in=>'ref',out=>'ref.out',cmd=>'+fill-from-fasta',args=>'-- -f {PATH}/norm.fa -c REF'); +test_vcf_plugin($opts,in=>'view',out=>'view.GTsubset.NA1.out',cmd=>'+GTsubset --no-version',args=>'-- -s NA00001'); +test_vcf_plugin($opts,in=>'view',out=>'view.GTsubset.NA1NA2.out',cmd=>'+GTsubset --no-version',args=>'-- -s NA00001,NA00002'); +test_vcf_plugin($opts,in=>'view',out=>'view.GTsubset.NA1NA2NA3.out',cmd=>'+GTsubset --no-version',args=>'-- -s NA00001,NA00002,NA00003'); +test_vcf_plugin($opts,in=>'mendelian',out=>'mendelian.1.out',cmd=>'+mendelian --no-version',args=>'-- -t mom1,dad1,child1 -d'); +test_vcf_plugin($opts,in=>'mendelian',out=>'mendelian.2.out',cmd=>'+mendelian --no-version',args=>'-- -t mom1,dad1,child1 -l+'); +test_vcf_plugin($opts,in=>'mendelian',out=>'mendelian.3.out',cmd=>'+mendelian --no-version',args=>'-- -t mom1,dad1,child1 -lx'); +test_vcf_concat($opts,in=>['concat.1.a','concat.1.b'],out=>'concat.1.vcf.out',do_bcf=>0,args=>''); +test_vcf_concat($opts,in=>['concat.1.a','concat.1.b'],out=>'concat.1.bcf.out',do_bcf=>1,args=>''); +test_vcf_concat($opts,in=>['concat.2.a','concat.2.b'],out=>'concat.2.vcf.out',do_bcf=>0,args=>'-a'); +test_vcf_concat($opts,in=>['concat.2.a','concat.2.b'],out=>'concat.2.bcf.out',do_bcf=>1,args=>'-a'); +test_vcf_concat($opts,in=>['concat.2.a','concat.2.b'],out=>'concat.4.vcf.out',do_bcf=>0,args=>'-aD'); +test_vcf_concat($opts,in=>['concat.2.a','concat.2.b'],out=>'concat.4.bcf.out',do_bcf=>1,args=>'-aD'); +test_vcf_concat($opts,in=>['concat.3.a','concat.3.b','concat.3.0','concat.3.c','concat.3.d','concat.3.e','concat.3.f'],out=>'concat.3.vcf.out',do_bcf=>0,args=>'-l'); +test_vcf_concat($opts,in=>['concat.3.a','concat.3.b','concat.3.0','concat.3.c','concat.3.d','concat.3.e','concat.3.f'],out=>'concat.3.bcf.out',do_bcf=>1,args=>'-l'); +test_naive_concat($opts,name=>'naive_concat',max_hdr_lines=>10000,max_body_lines=>10000,nfiles=>10); +test_vcf_reheader($opts,in=>'reheader',out=>'reheader.1.out',header=>'reheader.hdr'); +test_vcf_reheader($opts,in=>'reheader',out=>'reheader.2.out',samples=>'reheader.samples'); +test_vcf_reheader($opts,in=>'reheader',out=>'reheader.2.out',samples=>'reheader.samples2'); +test_vcf_reheader($opts,in=>'reheader',out=>'reheader.3.out',samples=>'reheader.samples3'); +test_vcf_reheader($opts,in=>'reheader',out=>'reheader.4.out',samples=>'reheader.samples4'); +test_vcf_reheader($opts,in=>'empty',out=>'reheader.empty.out',header=>'reheader.empty.hdr'); +test_rename_chrs($opts,in=>'annotate'); +test_vcf_convert($opts,in=>'convert',out=>'convert.gs.gt.gen',args=>'-g -,.'); +test_vcf_convert($opts,in=>'convert',out=>'convert.gs.gt.samples',args=>'-g .,-'); +test_vcf_convert($opts,in=>'convert',out=>'convert.gs.pl.gen',args=>'-g -,. --tag PL'); +test_vcf_convert($opts,in=>'convert',out=>'convert.gs.pl.samples',args=>'-g .,- --tag PL'); +test_vcf_convert($opts,in=>'check',out=>'check.gs.vcfids.gen',args=>'-g -,. --vcf-ids'); +test_vcf_convert($opts,in=>'check',out=>'check.gs.vcfids.samples',args=>'-g .,- --vcf-ids'); +test_vcf_convert($opts,in=>'check',out=>'check.gs.chrom.gen',args=>'-g -,. --chrom'); +test_vcf_convert($opts,in=>'check',out=>'check.gs.chrom.samples',args=>'-g .,- --chrom'); +test_vcf_convert($opts,in=>'check',out=>'check.gs.vcfids_chrom.gen',args=>'-g -,. --chrom --vcf-ids'); +test_vcf_convert($opts,in=>'check',out=>'check.gs.vcfids_chrom.samples',args=>'-g .,- --chrom --vcf-ids'); +test_vcf_convert($opts,in=>'convert',out=>'convert.hls.haps',args=>'-h -,.,.'); +test_vcf_convert($opts,in=>'convert',out=>'convert.hls.legend',args=>'-h .,-,.'); +test_vcf_convert($opts,in=>'convert',out=>'convert.hls.samples',args=>'-h .,.,-'); +test_vcf_convert_hls2vcf($opts,h=>'convert.hls.gt.hap',l=>'convert.hls.gt.legend',s=>'convert.hls.gt.samples',out=>'convert.gt.noHead.vcf',args=>'-H'); +test_vcf_convert_hs2vcf($opts,h=>'convert.hs.gt.hap',s=>'convert.hs.gt.samples',out=>'convert.gt.noHead.vcf',args=>'--hapsample2vcf'); +test_vcf_convert($opts,in=>'convert',out=>'convert.hs.hap',args=>'--hapsample -,.'); +test_vcf_convert($opts,in=>'convert',out=>'convert.hs.sample',args=>'--hapsample .,-'); +test_vcf_convert_gvcf($opts,in=>'convert.gvcf',out=>'convert.gvcf.out',fa=>'gvcf.fa',args=>'--gvcf2vcf'); +test_vcf_convert_tsv2vcf($opts,in=>'convert.23andme',out=>'convert.23andme.vcf',args=>'-c ID,CHROM,POS,AA -s SAMPLE1',fai=>'23andme'); +test_vcf_consensus($opts,in=>'consensus',out=>'consensus.1.out',fa=>'consensus.fa',mask=>'consensus.tab',args=>''); +test_vcf_consensus_chain($opts,in=>'consensus',out=>'consensus.1.chain',chain=>'consensus.1.chain',fa=>'consensus.fa',mask=>'consensus.tab',args=>''); +test_vcf_consensus($opts,in=>'consensus',out=>'consensus.2.out',fa=>'consensus.fa',mask=>'consensus.tab',args=>'-H 1'); +test_vcf_consensus_chain($opts,in=>'consensus',out=>'consensus.2.chain',chain=>'consensus.2.chain',fa=>'consensus.fa',mask=>'consensus.tab',args=>'-H 1'); +test_vcf_consensus($opts,in=>'consensus',out=>'consensus.3.out',fa=>'consensus.fa',mask=>'consensus.tab',args=>'-i'); +test_vcf_consensus_chain($opts,in=>'consensus',out=>'consensus.3.chain',chain=>'consensus.3.chain',fa=>'consensus.fa',mask=>'consensus.tab',args=>'-i'); +test_vcf_consensus($opts,in=>'consensus',out=>'consensus.4.out',fa=>'consensus.fa',args=>'-H 1'); +test_vcf_consensus_chain($opts,in=>'consensus',out=>'consensus.4.chain',chain=>'consensus.4.chain',fa=>'consensus.fa',args=>'-H 1'); +test_vcf_consensus($opts,in=>'consensus2',out=>'consensus2.1.out',fa=>'consensus2.fa',args=>'-H 1'); +test_vcf_consensus($opts,in=>'consensus2',out=>'consensus2.2.out',fa=>'consensus2.fa',args=>'-H 2'); +test_vcf_consensus($opts,in=>'empty',out=>'consensus.5.out',fa=>'consensus.fa',args=>''); +test_mpileup($opts,in=>[qw(1 2 3)],out=>'mpileup/mpileup.1.out',args=>q[-r17:100-150],test_list=>1); +test_mpileup($opts,in=>[qw(1 2 3)],out=>'mpileup/mpileup.2.out',args=>q[-a DP,DV -r17:100-600]); # test files from samtools mpileup test suite +test_mpileup($opts,in=>[qw(1)],out=>'mpileup/mpileup.3.out',args=>q[-B --ff 0x14 -r17:1050-1060]); # test file converted to vcf from samtools mpileup test suite +test_mpileup($opts,in=>[qw(1 2 3)],out=>'mpileup/mpileup.4.out',args=>q[-a DP,DPR,DV,DP4,INFO/DPR,SP -r17:100-600]); #test files from samtools mpileup test suite +test_mpileup($opts,in=>[qw(1 2 3)],out=>'mpileup/mpileup.5.out',args=>q[-a DP,AD,ADF,ADR,SP,INFO/AD,INFO/ADF,INFO/ADR -r17:100-600]); +test_mpileup($opts,in=>[qw(1 2 3)],out=>'mpileup/mpileup.6.out',args=>q[-a DP,DV -r17:100-600 --gvcf 0,2,5]); +test_mpileup($opts,in=>[qw(1 2 3)],out=>'mpileup/mpileup.6.out',args=>q[-a DP,DV -r17:100-200,17:201-300,17:301-400,17:401-500,17:501-600 --gvcf 0,2,5]); +test_mpileup($opts,in=>[qw(1 2 3)],out=>'mpileup/mpileup.7.out',args=>q[-r17:100-150 -s HG00101,HG00102]); +test_mpileup($opts,in=>[qw(1 2 3)],out=>'mpileup/mpileup.7.out',args=>q[-r17:100-150 -S {PATH}/mplp.samples]); +test_mpileup($opts,in=>[qw(1 2 3)],out=>'mpileup/mpileup.8.out',args=>q[-r17:100-150 -s ^HG00101,HG00102]); +test_mpileup($opts,in=>[qw(1 2 3)],out=>'mpileup/mpileup.8.out',args=>q[-r17:100-150 -S ^{PATH}/mplp.samples]); +test_mpileup($opts,in=>[qw(1 2 3)],out=>'mpileup/mpileup.9.out',args=>q[-t17:100-150 -S {PATH}/mplp.9.samples]); +test_mpileup($opts,in=>[qw(1 2 3)],out=>'mpileup/mpileup.10.out',args=>q[-t17:100-150 -G {PATH}/mplp.10.samples]); +test_mpileup($opts,in=>[qw(3)],out=>'mpileup/mpileup.11.out',args=>q[]); +test_mpileup($opts,in=>[qw(3 4)],out=>'mpileup/mpileup.11.out',args=>q[-s HG00102]); +test_mpileup($opts,in=>[qw(3 4)],out=>'mpileup/mpileup.11.out',args=>q[-s ^HG99999]); +test_mpileup($opts,in=>[qw(3 4)],out=>'mpileup/mpileup.11.out',args=>q[-G {PATH}/mplp.11.rgs]); +test_csq($opts,in=>'csq',out=>'csq.1.out',cmd=>'-f {PATH}/csq.fa -g {PATH}/csq.gff3'); +test_csq_real($opts,in=>'csq'); + +print "\nNumber of tests:\n"; +printf " total .. %d\n", $$opts{nok}+$$opts{nfailed}; +printf " passed .. %d\n", $$opts{nok}; +printf " failed .. %d\n", $$opts{nfailed}; +print "\n"; + +exit ($$opts{nfailed} != 0); + +#-------------------- + +sub error +{ + my (@msg) = @_; + if ( scalar @msg ) { confess @msg; } + print + "About: htslib consistency test script\n", + "Usage: test.pl [OPTIONS]\n", + "Options:\n", + " -p, --plugins Test also plugins, requires libhts.so.\n", + " -r, --redo-outputs Recreate expected output files.\n", + " -t, --temp-dir When given, temporary files will not be removed.\n", + " -h, -?, --help This help message.\n", + "\n"; + exit -1; +} +sub parse_params +{ + my $opts = { bgzip=>"bgzip", keep_files=>0, nok=>0, nfailed=>0, tabix=>"tabix", plugins=>0 }; + my $help; + Getopt::Long::Configure('bundling'); + my $ret = GetOptions ( + 'e|exec=s' => sub { my ($tool, $path) = split /=/, $_[1]; $$opts{$tool} = $path if $path }, + 't|temp-dir:s' => \$$opts{keep_files}, + 'p|plugins' => \$$opts{test_plugins}, + 'r|redo-outputs' => \$$opts{redo_outputs}, + 'h|?|help' => \$help + ); + if ( !$ret or $help ) { error(); } + $$opts{tmp} = $$opts{keep_files} ? $$opts{keep_files} : tempdir(CLEANUP=>1); + if ( $$opts{keep_files} ) { cmd("mkdir -p $$opts{keep_files}"); } + $$opts{path} = $FindBin::RealBin; + $$opts{bin} = $FindBin::RealBin; + $$opts{bin} =~ s{/test/?$}{}; + return $opts; +} +sub _cmd +{ + my ($cmd) = @_; + my $kid_io; + my @out; + my $pid = open($kid_io, "-|"); + if ( !defined $pid ) { error("Cannot fork: $!"); } + if ($pid) + { + # parent + @out = <$kid_io>; + close($kid_io); + } + else + { + # child + exec('/bin/bash', '-o','pipefail','-c', $cmd) or error("Cannot execute the command [/bin/sh -o pipefail -c $cmd]: $!"); + } + return ($? >> 8, join('',@out)); +} +sub cmd +{ + my ($cmd) = @_; + my ($ret,$out) = _cmd($cmd); + if ( $ret ) { error("The command failed: $cmd\n", $out); } + return $out; +} +sub test_cmd +{ + my ($opts,%args) = @_; + if ( !exists($args{out}) ) + { + if ( !exists($args{in}) ) { error("FIXME: expected out or in key\n"); } + $args{out} = "$args{in}.out"; + } + my ($package, $filename, $line, $test)=caller(1); + $test =~ s/^.+:://; + + print "$test:\n"; + print "\t$args{cmd}\n"; + + my ($ret,$out) = _cmd("$args{cmd}"); + if ( $ret ) { failed($opts,$test,"Non-zero status $ret"); return; } + if ( $$opts{redo_outputs} && -e "$$opts{path}/$args{out}" ) + { + rename("$$opts{path}/$args{out}","$$opts{path}/$args{out}.old"); + open(my $fh,'>',"$$opts{path}/$args{out}") or error("$$opts{path}/$args{out}: $!"); + print $fh $out; + close($fh); + my ($ret,$out) = _cmd("diff -q $$opts{path}/$args{out} $$opts{path}/$args{out}.old"); + if ( !$ret && $out eq '' ) { unlink("$$opts{path}/$args{out}.old"); } + else + { + print "\tthe expected output changed, saving:\n"; + print "\t old .. $$opts{path}/$args{out}.old\n"; + print "\t new .. $$opts{path}/$args{out}\n"; + } + } + my $exp = ''; + if ( exists($args{exp}) ) { $exp = $args{exp}; } + elsif ( open(my $fh,'<',"$$opts{path}/$args{out}") ) + { + my @exp = <$fh>; + $exp = join('',@exp); + close($fh); + } + else + { + open(my $fh,'>',"$$opts{path}/$args{out}.new") or error("$$opts{path}/$args{out}.new: $!"); + print $fh $out; + close($fh); + if ( !$$opts{redo_outputs} ) { failed($opts,$test,"$$opts{path}/$args{out}.new"); return; } + } + + if ( $exp ne $out ) + { + open(my $fh,'>',"$$opts{path}/$args{out}.new") or error("$$opts{path}/$args{out}.new"); + print $fh $out; + close($fh); + if ( !-e "$$opts{path}/$args{out}" && !exists($args{exp}) ) + { + rename("$$opts{path}/$args{out}.new","$$opts{path}/$args{out}") or error("rename $$opts{path}/$args{out}.new $$opts{path}/$args{out}: $!"); + print "\tthe file with expected output does not exist, creating new one:\n"; + print "\t\t$$opts{path}/$args{out}\n"; + } + else + { + if ( exists($args{exp}) ) + { + open(my $fh,'>',"$$opts{path}/$args{out}") or error("$$opts{path}/$args{out}"); + print $fh $exp; + close($fh); + } + failed($opts,$test,"The outputs differ:\n\t\t$$opts{path}/$args{out}\n\t\t$$opts{path}/$args{out}.new"); + } + return; + } + passed($opts,$test); +} +sub failed +{ + my ($opts,$test,$reason) = @_; + $$opts{nfailed}++; + if ( defined $reason ) { print "\n\t$reason"; } + print "\n.. failed ...\n\n"; +} +sub passed +{ + my ($opts,$test) = @_; + $$opts{nok}++; + print ".. ok\n\n"; +} +sub is_file_newer +{ + my ($afile,$bfile) = @_; + my (@astat) = stat($afile) or return 0; + my (@bstat) = stat($bfile) or return 0; + if ( $astat[9]>$bstat[9] ) { return 1 } + return 0; +} +sub bgzip_tabix +{ + my ($opts,%args) = @_; + my $file = "$args{file}.$args{suffix}"; + if ( $$opts{redo_outputs} or !-e "$$opts{tmp}/$file.gz" or is_file_newer("$$opts{path}/$file","$$opts{tmp}/$file.gz") ) + { + cmd("cat $$opts{path}/$file | $$opts{bgzip} -c > $$opts{tmp}/$file.gz"); + } + if ( $$opts{redo_outputs} or !-e "$$opts{tmp}/$file.gz.tbi" or is_file_newer("$$opts{tmp}/$file.gz","$$opts{tmp}/$file.gz.tbi") ) + { + cmd("$$opts{tabix} -f $args{args} $$opts{tmp}/$file.gz"); + } +} +sub bgzip_tabix_vcf +{ + my ($opts,$file) = @_; + bgzip_tabix($opts,file=>$file,suffix=>'vcf',args=>'-p vcf'); +} + + +# The tests -------------------------- + +sub test_tabix +{ + my ($opts,%args) = @_; + bgzip_tabix_vcf($opts,$args{in}); + test_cmd($opts,%args,cmd=>"$$opts{tabix} $$opts{tmp}/$args{in}.vcf.gz $args{reg}"); + + cmd("$$opts{bin}/bcftools view -Ob $$opts{tmp}/$args{in}.vcf.gz > $$opts{tmp}/$args{in}.bcf"); + cmd("$$opts{bin}/bcftools index -f $$opts{tmp}/$args{in}.bcf"); + test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools view -H $$opts{tmp}/$args{in}.bcf $args{reg}"); +} +sub test_index +{ + my ($opts,%args) = @_; + cmd("$$opts{bin}/bcftools view -Oz $$opts{path}/$args{in}.vcf > $$opts{tmp}/$args{in}.vcf.gz"); + cmd("$$opts{bin}/bcftools index -f $$opts{tmp}/$args{in}.vcf.gz"); + test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools view -H $$opts{tmp}/$args{in}.vcf.gz $args{reg}"); + + cmd("$$opts{bin}/bcftools view -Ob $$opts{path}/$args{in}.vcf > $$opts{tmp}/$args{in}.bcf"); + cmd("$$opts{bin}/bcftools index -f $$opts{tmp}/$args{in}.bcf"); + test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools view -H $$opts{tmp}/$args{in}.bcf $args{reg}"); + + # output path + unlink("$$opts{tmp}/$args{in}.bcf.csi", "$$opts{tmp}/$args{in}.bcf.csi", "$$opts{tmp}/$args{in}.vcf.gz.tbi"); + cmd("$$opts{bin}/bcftools index -fo $$opts{tmp}/$args{in}.csi $$opts{tmp}/$args{in}.bcf"); + test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools view -H $$opts{tmp}/$args{in}.bcf $args{reg}"); + + # streaming + cmd("$$opts{bin}/bcftools view -Oz $$opts{path}/$args{in}.vcf | tee $$opts{tmp}/$args{in}.vcf.gz | $$opts{bin}/bcftools index -fo $$opts{tmp}/$args{in}.vcf.gz.csi"); + test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools view -H $$opts{tmp}/$args{in}.vcf.gz $args{reg}"); + + cmd("$$opts{bin}/bcftools view -Ob $$opts{path}/$args{in}.vcf | tee $$opts{tmp}/$args{in}.bcf | $$opts{bin}/bcftools index -fo $$opts{tmp}/$args{in}.bcf.csi"); + test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools view -H $$opts{tmp}/$args{in}.bcf $args{reg}"); +} + +sub test_vcf_idxstats +{ + my ($opts,%args) = @_; + cmd("$$opts{bin}/bcftools view -Oz $$opts{path}/$args{in}.vcf > $$opts{tmp}/$args{in}.vcf.gz"); + cmd("$$opts{bin}/bcftools index --tbi -f $$opts{tmp}/$args{in}.vcf.gz"); + test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools index $args{args} $$opts{tmp}/$args{in}.vcf.gz"); + unlink("$$opts{tmp}/$args{in}.vcf.gz.tbi"); + cmd("$$opts{bin}/bcftools index --csi -f $$opts{tmp}/$args{in}.vcf.gz"); + test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools index $args{args} $$opts{tmp}/$args{in}.vcf.gz"); + unlink("$$opts{tmp}/$args{in}.vcf.gz.csi"); + + cmd("$$opts{bin}/bcftools view -Ob $$opts{path}/$args{in}.vcf > $$opts{tmp}/$args{in}.bcf"); + cmd("$$opts{bin}/bcftools index -f $$opts{tmp}/$args{in}.bcf"); + test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools index $args{args} $$opts{tmp}/$args{in}.bcf"); +} + +sub test_vcf_check +{ + my ($opts,%args) = @_; + bgzip_tabix_vcf($opts,$args{in}); + test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools stats -s - $$opts{tmp}/$args{in}.vcf.gz | grep -v '^# The command' | grep -v '^# This' | grep -v '^ID\t'"); + test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools view -Ob $$opts{tmp}/$args{in}.vcf.gz | $$opts{bin}/bcftools stats -s - | grep -v '^# The command' | grep -v '^# This' | grep -v '^ID\t'"); +} + +sub test_vcf_check_merge +{ + my ($opts,%args) = @_; + bgzip_tabix_vcf($opts,$args{in}); + cmd("$$opts{bin}/bcftools stats -r 1 $$opts{tmp}/$args{in}.vcf.gz > $$opts{tmp}/$args{in}.1.chk"); + cmd("$$opts{bin}/bcftools stats -r 2 $$opts{tmp}/$args{in}.vcf.gz > $$opts{tmp}/$args{in}.2.chk"); + cmd("$$opts{bin}/bcftools stats -r 3 $$opts{tmp}/$args{in}.vcf.gz > $$opts{tmp}/$args{in}.3.chk"); + cmd("$$opts{bin}/bcftools stats -r 4 $$opts{tmp}/$args{in}.vcf.gz > $$opts{tmp}/$args{in}.4.chk"); + test_cmd($opts,%args,cmd=>"$$opts{bin}/misc/plot-vcfstats -m $$opts{tmp}/$args{in}.1.chk $$opts{tmp}/$args{in}.2.chk $$opts{tmp}/$args{in}.3.chk $$opts{tmp}/$args{in}.4.chk 2>/dev/null | grep -v 'plot-vcfstats' | grep -v '^# The command' | grep -v '^# This' | grep -v '^ID\t'"); +} + +sub test_vcf_stats +{ + my ($opts,%args) = @_; + my $files = ''; + for my $file (@{$args{in}}) + { + bgzip_tabix_vcf($opts,$file); + $files .= " $$opts{tmp}/$file.vcf.gz"; + } + test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools stats $args{args} $files | grep -v '^#' | grep -v '^ID\t'"); +} +sub test_vcf_merge +{ + my ($opts,%args) = @_; + my @files; + for my $file (@{$args{in}}) + { + bgzip_tabix_vcf($opts,$file); + push @files, "$$opts{tmp}/$file.vcf.gz"; + } + my $args = exists($args{args}) ? $args{args} : ''; + my $files = join(' ',@files); + test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools merge --no-version $args $files"); + test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools merge -Ob $args $files | $$opts{bin}/bcftools view | grep -v ^##bcftools_"); +} +sub test_vcf_isec +{ + my ($opts,%args) = @_; + my @files; + for my $file (@{$args{in}}) + { + bgzip_tabix_vcf($opts,$file); + push @files, "$$opts{tmp}/$file.vcf.gz"; + } + my $files = join(' ',@files); + test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools isec $args{args} $files 2>/dev/null"); + test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools isec -Ob $args{args} $files 2>/dev/null"); +} +sub test_vcf_isec2 +{ + my ($opts,%args) = @_; + my @files; + for my $file (@{$args{vcf_in}}) + { + bgzip_tabix_vcf($opts,$file); + push @files, "$$opts{tmp}/$file.vcf.gz"; + } + my $files = join(' ',@files); + bgzip_tabix($opts,file=>$args{tab_in},suffix=>'tab',args=>'-s 1 -b 2 -e 3'); + test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools isec --no-version $args{args} -T $$opts{tmp}/$args{tab_in}.tab.gz $files 2>/dev/null"); + test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools isec -Ob $args{args} -T $$opts{tmp}/$args{tab_in}.tab.gz $files 2>/dev/null | $$opts{bin}/bcftools view | grep -v ^##bcftools_"); +} +sub test_vcf_query +{ + my ($opts,%args) = @_; + bgzip_tabix_vcf($opts,$args{in}); + test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools query $args{args} $$opts{tmp}/$args{in}.vcf.gz"); + test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools view -Ob $$opts{tmp}/$args{in}.vcf.gz | $$opts{bin}/bcftools query $args{args}"); +} +sub test_vcf_convert +{ + my ($opts,%args) = @_; + bgzip_tabix_vcf($opts,$args{in}); + test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools convert $args{args} $$opts{tmp}/$args{in}.vcf.gz 2>/dev/null"); + test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools view -Ob $$opts{tmp}/$args{in}.vcf.gz | $$opts{bin}/bcftools convert $args{args} 2>/dev/null"); +} +sub test_vcf_convert_hls2vcf +{ + my ($opts,%args) = @_; + my $hls = join(',', map { "$$opts{path}/$_" }( $args{h}, $args{l}, $args{s} ) ); + test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools convert $args{args} $hls 2>/dev/null | grep -v ^##"); + test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools convert $args{args} $hls -Ou 2>/dev/null | $$opts{bin}/bcftools view | grep -v ^##"); +} +sub test_vcf_convert_hs2vcf +{ + my ($opts,%args) = @_; + my $hs = join(',', map { "$$opts{path}/$_" }( $args{h}, $args{s} ) ); + test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools convert $args{args} $hs 2>/dev/null | grep -v ^##"); + test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools convert $args{args} $hs -Ou 2>/dev/null | $$opts{bin}/bcftools view | grep -v ^##"); +} +sub test_vcf_convert_gvcf +{ + my ($opts,%args) = @_; + bgzip_tabix_vcf($opts,$args{in}); + test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools convert --no-version $args{args} -f $$opts{path}/$args{fa} $$opts{tmp}/$args{in}.vcf.gz 2>/dev/null"); + test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools view -Ob $$opts{tmp}/$args{in}.vcf.gz | $$opts{bin}/bcftools convert $args{args} -f $$opts{path}/$args{fa} 2>/dev/null | grep -v ^##bcftools"); +} +sub test_vcf_convert_tsv2vcf +{ + my ($opts,%args) = @_; + my $params = ''; + if ( exists($args{args}) ) { $params .= " $args{args}"; } + if ( exists($args{fai} ) ) { $params .= " -f $$opts{path}/$args{fai}.fa"; } + test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools convert --no-version $params --tsv2vcf $$opts{path}/$args{in} 2>/dev/null"); + test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools convert -Ou $params --tsv2vcf $$opts{path}/$args{in} 2>/dev/null | $$opts{bin}/bcftools view | grep -v ^##bcftools_"); +} +sub test_vcf_norm +{ + my ($opts,%args) = @_; + bgzip_tabix_vcf($opts,$args{in}); + my $params = ''; + if ( exists($args{args}) ) { $params .= " $args{args}"; } + if ( exists($args{fai} ) ) { $params .= " -f $$opts{path}/$args{fai}.fa"; } + test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools norm --no-version $params $$opts{tmp}/$args{in}.vcf.gz 2>/dev/null"); + test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools norm -Ob $params $$opts{tmp}/$args{in}.vcf.gz 2>/dev/null | $$opts{bin}/bcftools view | grep -v ^##bcftools_"); +} +sub test_vcf_view +{ + my ($opts,%args) = @_; + bgzip_tabix_vcf($opts,$args{in}); + + if ( !exists($args{args}) ) { $args{args} = ''; } + if ( exists($args{tgts}) ) { $args{args} .= "-T $$opts{path}/$args{tgts}"; } + test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools view --no-version $args{args} $$opts{tmp}/$args{in}.vcf.gz $args{reg}"); + unless ($args{args} =~ /-H/) { + test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools view -Ob $args{args} $$opts{tmp}/$args{in}.vcf.gz $args{reg} | $$opts{bin}/bcftools view | grep -v ^##bcftools_"); + } +} +sub test_vcf_call +{ + my ($opts,%args) = @_; + $args{args} =~ s/{PATH}/$$opts{path}/g; + test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools call --no-version $args{args} $$opts{path}/$args{in}.vcf 2>/dev/null"); + test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools call -Ob $args{args} $$opts{path}/$args{in}.vcf 2>/dev/null | $$opts{bin}/bcftools view | grep -v ^##bcftools_"); +} +sub test_vcf_call_cAls +{ + my ($opts,%args) = @_; + bgzip_tabix($opts,file=>$args{tab},suffix=>'tab',args=>'-s1 -b2 -e2'); + test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools call --no-version -mA -C alleles -T $$opts{tmp}/$args{tab}.tab.gz $$opts{path}/$args{in}.vcf 2>/dev/null"); + test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools call -Ob -mA -C alleles -T $$opts{tmp}/$args{tab}.tab.gz $$opts{path}/$args{in}.vcf 2>/dev/null | $$opts{bin}/bcftools view | grep -v ^##bcftools_"); +} +sub test_vcf_filter +{ + my ($opts,%args) = @_; + my $pipe = 'grep -v ^##bcftools_'; + if ( exists($args{fmt}) ) + { + $pipe = "$$opts{bin}/bcftools query -f '$args{fmt}'"; + } + test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools filter $args{args} $$opts{path}/$args{in}.vcf | $pipe"); + test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools filter -Ob $args{args} $$opts{path}/$args{in}.vcf | $$opts{bin}/bcftools view | $pipe"); +} +sub test_vcf_regions +{ + my ($opts,%args) = @_; + bgzip_tabix_vcf($opts,$args{in}); + + # regions vs targets, holding tab in memory + my $query = q[%CHROM %POS %REF,%ALT\n]; + test_cmd($opts,cmd=>qq[$$opts{bin}/bcftools query -f'$query' -T $$opts{path}/$args{in}.tab $$opts{tmp}/$args{in}.vcf.gz],out=>'regions.out'); + test_cmd($opts,cmd=>qq[$$opts{bin}/bcftools view -Ob $$opts{tmp}/$args{in}.vcf.gz | $$opts{bin}/bcftools query -f'$query' -T $$opts{path}/$args{in}.tab],out=>'regions.out'); + test_cmd($opts,cmd=>qq[$$opts{bin}/bcftools query -f'$query' -R $$opts{path}/$args{in}.tab $$opts{tmp}/$args{in}.vcf.gz],out=>'regions.out'); + + # regions vs targets, reading tabix-ed tab + cmd(qq[cat $$opts{path}/$args{in}.tab | $$opts{bgzip} -c > $$opts{tmp}/$args{in}.tab.gz]); + cmd(qq[$$opts{tabix} -f -s1 -b2 -e3 $$opts{tmp}/$args{in}.tab.gz]); + test_cmd($opts,cmd=>qq[$$opts{bin}/bcftools query -f'$query' -T $$opts{tmp}/$args{in}.tab.gz $$opts{tmp}/$args{in}.vcf.gz],out=>'regions.out'); + test_cmd($opts,cmd=>qq[$$opts{bin}/bcftools view -Ob $$opts{tmp}/$args{in}.vcf.gz | $$opts{bin}/bcftools query -f'$query' -T $$opts{tmp}/$args{in}.tab.gz],out=>'regions.out'); + test_cmd($opts,cmd=>qq[$$opts{bin}/bcftools query -f'$query' -R $$opts{tmp}/$args{in}.tab.gz $$opts{tmp}/$args{in}.vcf.gz],out=>'regions.out'); + + # regions vs targets, holding bed in memory + cmd(qq[cat $$opts{path}/$args{in}.tab | awk '{OFS="\\t"}{print \$1,\$2-1,\$3}' > $$opts{tmp}/$args{in}.bed]); + test_cmd($opts,cmd=>qq[$$opts{bin}/bcftools query -f'$query' -T $$opts{tmp}/$args{in}.bed $$opts{tmp}/$args{in}.vcf.gz],out=>'regions.out'); + test_cmd($opts,cmd=>qq[$$opts{bin}/bcftools view -Ob $$opts{tmp}/$args{in}.vcf.gz | $$opts{bin}/bcftools query -f'$query' -T $$opts{tmp}/$args{in}.bed],out=>'regions.out'); + test_cmd($opts,cmd=>qq[$$opts{bin}/bcftools query -f'$query' -R $$opts{tmp}/$args{in}.bed $$opts{tmp}/$args{in}.vcf.gz],out=>'regions.out'); + + # regions vs targets, reading tabix-ed bed + cmd(qq[cat $$opts{tmp}/$args{in}.bed | $$opts{bgzip} -c > $$opts{tmp}/$args{in}.bed.gz]); + cmd(qq[$$opts{tabix} -f -p bed $$opts{tmp}/$args{in}.bed.gz]); + test_cmd($opts,cmd=>qq[$$opts{bin}/bcftools query -f'$query' -T $$opts{tmp}/$args{in}.bed.gz $$opts{tmp}/$args{in}.vcf.gz],out=>'regions.out'); + test_cmd($opts,cmd=>qq[$$opts{bin}/bcftools view -Ob $$opts{tmp}/$args{in}.vcf.gz | $$opts{bin}/bcftools query -f'$query' -T $$opts{tmp}/$args{in}.bed.gz],out=>'regions.out'); + test_cmd($opts,cmd=>qq[$$opts{bin}/bcftools query -f'$query' -R $$opts{tmp}/$args{in}.bed.gz $$opts{tmp}/$args{in}.vcf.gz],out=>'regions.out'); +} +sub test_usage +{ + my ($opts,%args) = @_; + + my $test = "test_usage"; + print "$test:\n"; + print "\t$args{cmd}\n"; + + my $tty_input; + if (-t) { + $args{redirection} = ""; # no redirection necessary + } + elsif (eval { require IO::Pty }) { + $tty_input = new IO::Pty; + # ensure stdin is a terminal, so that subcommands display their usage + $args{redirection} = "<'" . $tty_input->ttyname . "'"; + } + else { + warn "$0: module IO::Pty not found; skipping usage tests\n"; + return; + } + + my $command = $args{cmd}; + my $commandpath = $$opts{bin}."/".$command; + my ($ret,$out) = _cmd("$commandpath $args{redirection} 2>&1"); + if ( $out =~ m/\/bin\/bash.*no.*such/i ) { failed($opts,$test,"could not run $commandpath: $out"); return; } + + my @sections = ($out =~ m/(^[A-Za-z]+.*?)(?:(?=^[A-Za-z]+:)|\z)/msg); + + my $have_usage = 0; + my $have_version = 0; + my $have_subcommands = 0; + my $usage = ""; + my @subcommands = (); + foreach my $section (@sections) { + if ( $section =~ m/^usage/i ) { + $have_usage = 1; + $section =~ s/^[[:word:]]+[[:punct:]]?[[:space:]]*//; + $usage = $section; + } elsif ( $section =~ m/^version/i ) { + $have_version = 1; + } elsif ( $section =~ m/^command/i ) { + $have_subcommands = 1; + foreach my $line (split /\n/, $section) { + push @subcommands, $1 if $line =~ /^\s{2,}(\w+)\s{2,}/; + } + } + } + + if ( !$have_usage ) { failed($opts,$test,"did not have Usage:"); return; } + if ( !$have_version ) { failed($opts,$test,"did not have Version:"); return; } + if ( !$have_subcommands ) { failed($opts,$test,"did not have Commands:"); return; } + + if ( !($usage =~ m/$command/) ) { failed($opts,$test,"usage did not mention $command"); return; } + + if ( scalar(@subcommands) < 1 ) { failed($opts,$test,"could not parse subcommands"); return; } + + passed($opts,$test); + + # now test subcommand usage as well + foreach my $subcommand (@subcommands) { + test_usage_subcommand($opts,%args,subcmd=>$subcommand); + } +} +sub test_usage_subcommand +{ + my ($opts,%args) = @_; + + my $test = "test_usage_subcommand"; + print "$test:\n"; + print "\t$args{cmd} $args{subcmd}\n"; + + my $command = $args{cmd}; + my $subcommand = $args{subcmd}; + my $commandpath = $$opts{bin}."/".$command; + my ($ret,$out) = _cmd("$commandpath $subcommand $args{redirection} 2>&1"); + if ( $out =~ m/\/bin\/bash.*no.*such/i ) { failed($opts,$test,"could not run $commandpath $subcommand: $out"); return; } + + my @sections = ($out =~ m/(^[A-Za-z]+.*?)(?:(?=^[A-Za-z]+:)|\z)/msg); + + my $have_usage = 0; + my $usage = ""; + foreach my $section (@sections) { + if ( $section =~ m/^usage/i ) { + $have_usage = 1; + $section =~ s/^[[:word:]]+[[:punct:]]?[[:space:]]*//; + $usage = $section; + } + } + + if ( !$have_usage ) { failed($opts,$test,"did not have Usage:"); return; } + + if ( !($usage =~ m/$command[[:space:]]+$subcommand/) ) { failed($opts,$test,"usage did not mention $command $subcommand"); return; } + + passed($opts,$test); +} +sub test_vcf_annotate +{ + my ($opts,%args) = @_; + my ($annot_fname,$in_fname,$hdr); + if ( exists($args{tab}) ) + { + bgzip_tabix($opts,file=>$args{tab},suffix=>'tab',args=>'-s1 -b2 -e2'); + $annot_fname = "-a $$opts{tmp}/$args{tab}.tab.gz"; + $in_fname = "$$opts{path}/$args{in}.vcf"; + $hdr = -e "$$opts{path}/$args{in}.hdr" ? "-h $$opts{path}/$args{in}.hdr" : ''; + } + elsif ( exists($args{vcf}) ) + { + bgzip_tabix_vcf($opts,"$args{in}"); + bgzip_tabix_vcf($opts,$args{vcf}); + $annot_fname = "-a $$opts{tmp}/$args{vcf}.vcf.gz"; + $in_fname = "$$opts{tmp}/$args{in}.vcf.gz"; + $hdr = ''; + } + else + { + $in_fname = "$$opts{path}/$args{in}.vcf"; + $annot_fname = ''; + $hdr = ''; + } + test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools annotate $annot_fname $hdr $args{args} $in_fname 2>/dev/null | $$opts{bin}/bcftools view | grep -v ^##bcftools_"); + test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools annotate -Ob $annot_fname $hdr $args{args} $in_fname 2>/dev/null | $$opts{bin}/bcftools view | grep -v ^##bcftools_"); +} +sub test_vcf_plugin +{ + my ($opts,%args) = @_; + if ( !$$opts{test_plugins} ) { return; } + $ENV{BCFTOOLS_PLUGINS} = "$$opts{bin}/plugins"; + if ( !exists($args{args}) ) { $args{args} = ''; } + $args{args} =~ s/{PATH}/$$opts{path}/g; + $args{cmd} =~ s/{PATH}/$$opts{path}/g; + bgzip_tabix_vcf($opts,"$args{in}"); + test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools $args{cmd} $$opts{tmp}/$args{in}.vcf.gz $args{args} 2>/dev/null | grep -v ^##bcftools_"); + + cmd("$$opts{bin}/bcftools view -Ob $$opts{tmp}/$args{in}.vcf.gz > $$opts{tmp}/$args{in}.bcf"); + cmd("$$opts{bin}/bcftools index -f $$opts{tmp}/$args{in}.bcf"); + test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools $args{cmd} $$opts{tmp}/$args{in}.bcf $args{args} 2>/dev/null | grep -v ^##bcftools_"); +} +sub test_vcf_concat +{ + my ($opts,%args) = @_; + my $files; + for my $file (@{$args{in}}) + { + if ( $args{do_bcf} ) + { + cmd("$$opts{bin}/bcftools view --no-version -Ob $$opts{tmp}/$file.vcf.gz > $$opts{tmp}/$file.bcf"); + cmd("$$opts{bin}/bcftools index -f $$opts{tmp}/$file.bcf"); + $files .= " $$opts{tmp}/$file.bcf"; + } + else + { + bgzip_tabix_vcf($opts,$file); + $files .= " $$opts{tmp}/$file.vcf.gz"; + } + } + test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools concat --no-version $args{args} $files"); + test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools concat -Ob $args{args} $files | $$opts{bin}/bcftools view | grep -v ^##bcftools_"); +} +sub test_vcf_reheader +{ + my ($opts,%args) = @_; + cmd("$$opts{bin}/bcftools view --no-version -Ob $$opts{path}/$args{in}.vcf > $$opts{tmp}/$args{in}.bcf"); + cmd("$$opts{bin}/bcftools view --no-version -Oz $$opts{path}/$args{in}.vcf > $$opts{tmp}/$args{in}.vcf.gz"); + + my $arg = exists($args{header}) ? "-h $$opts{path}/$args{header}" : "-s $$opts{path}/$args{samples}"; + for my $file ("$$opts{path}/$args{in}.vcf","$$opts{tmp}/$args{in}.bcf","$$opts{tmp}/$args{in}.vcf.gz") + { + # bcf header lines can come in different order + my %bcf_args = (); + if ( $file=~/\.bcf$/ && -e "$$opts{path}/$args{out}.bcf" ) { %bcf_args = ( out=>"$args{out}.bcf" ); } + test_cmd($opts,%args,%bcf_args,cmd=>"$$opts{bin}/bcftools reheader $arg $file | $$opts{bin}/bcftools view --no-version"); + test_cmd($opts,%args,%bcf_args,cmd=>"cat $file | $$opts{bin}/bcftools reheader $arg | $$opts{bin}/bcftools view --no-version"); + } +} +sub test_rename_chrs +{ + my ($opts,%args) = @_; + cmd("$$opts{bin}/bcftools view -Ob $$opts{path}/$args{in}.vcf > $$opts{tmp}/$args{in}.bcf"); + cmd("$$opts{bin}/bcftools query -f'chr%CHROM\\t%POS\\n' $$opts{path}/$args{in}.vcf > $$opts{path}/rename.out.tmp"); + cmd("$$opts{bin}/bcftools query -f'%CHROM\\tchr%CHROM\\n' $$opts{path}/$args{in}.vcf | uniq > $$opts{tmp}/rename.map"); + my $prevfailed = $$opts{nfailed}; + for my $file ("$$opts{tmp}/$args{in}.bcf","$$opts{path}/$args{in}.vcf") + { + test_cmd($opts,%args,out=>"rename.out.tmp",cmd=>"$$opts{bin}/bcftools annotate --rename-chrs $$opts{tmp}/rename.map -Ov $file | $$opts{bin}/bcftools query -f'%CHROM\\t%POS\\n'"); + test_cmd($opts,%args,out=>"rename.out.tmp",cmd=>"$$opts{bin}/bcftools annotate --rename-chrs $$opts{tmp}/rename.map -Ob $file | $$opts{bin}/bcftools query -f'%CHROM\\t%POS\\n'"); + } + unlink "$$opts{path}/rename.out.tmp" if $$opts{nfailed} == $prevfailed; +} +sub test_vcf_consensus +{ + my ($opts,%args) = @_; + bgzip_tabix_vcf($opts,$args{in}); + my $mask = $args{mask} ? "-m $$opts{path}/$args{mask}" : ''; + my $chain = $args{chain} ? "-c $$opts{tmp}/$args{chain}" : ''; + test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools consensus $$opts{tmp}/$args{in}.vcf.gz -f $$opts{path}/$args{fa} $args{args} $mask $chain 2>/dev/null"); +} +sub test_vcf_consensus_chain +{ + my ($opts,%args) = @_; + bgzip_tabix_vcf($opts,$args{in}); + my $mask = $args{mask} ? "-m $$opts{path}/$args{mask}" : ''; + my $chain = $args{chain} ? "-c $$opts{tmp}/$args{chain}.new" : ''; + test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools consensus $$opts{tmp}/$args{in}.vcf.gz -f $$opts{path}/$args{fa} $args{args} $mask $chain > /dev/null 2>/dev/null; cat $$opts{tmp}/$args{chain}.new"); +} + +sub test_naive_concat +{ + my ($opts,%args) = @_; + + my $seed = srand(); + print STDERR "Random seed for test_naive_concat: $seed\n"; + + my @files = (); + my $exp = ''; + for (my $n=0; $n<$args{nfiles}; $n++) + { + my $nhdr = 1 + int(rand($args{max_hdr_lines})); + my $nbdy = int(rand($args{max_body_lines})); + my $file = "$$opts{tmp}/$args{name}.$n"; + push @files,$file; + + open(my $fh,'>',"$file.vcf") or error("$file.vcf: $!"); + print $fh "##fileformat=VCFv4.0\n"; + print $fh "##INFO=\n"; + print $fh "##contig=\n"; + for (my $i=0; $i<$nhdr; $i++) + { + my $x = rand; + print $fh "##INFO=\n"; + } + print $fh join("\t",'#CHROM','POS','ID','REF','ALT','QUAL','FILTER','INFO')."\n"; + + # let one of the files have no body + if ( $n!=3 ) + { + for (my $i=1; $i<=$nbdy; $i++) + { + my $x = int(rand(1000)); + my $line = join("\t",'1',$i,'.','A','C','.','.',"DP=$x")."\n"; + print $fh $line; + $exp .= $line; + } + } + close($fh) or error("close failed: $file.vcf"); + } + + for my $file (@files) + { + cmd("$$opts{bin}/bcftools view -Ob -o $file.bcf $file.vcf"); + cmd("$$opts{bin}/bcftools view -Oz -o $file.vcf.gz $file.vcf"); + } + + my $bcfs = join('.bcf ',@files).'.bcf'; + test_cmd($opts,exp=>$exp,out=>"concat.naive.bcf.out",cmd=>"$$opts{bin}/bcftools concat --naive $bcfs | $$opts{bin}/bcftools view -H"); + + my $vcfs = join('.vcf.gz ',@files).'.vcf.gz'; + test_cmd($opts,exp=>$exp,out=>"concat.naive.vcf.out",cmd=>"$$opts{bin}/bcftools concat --naive $vcfs | $$opts{bin}/bcftools view -H"); +} + +sub test_mpileup +{ + my ($opts,%args) = @_; + + if ($args{test_list}) + { + # make a local copy, create bams, index the bams and the reference + open(my $fh1,'>',"$$opts{tmp}/mpileup.bam.list") or error("$$opts{tmp}/mpileup.bam.list: $!"); + open(my $fh2,'>',"$$opts{tmp}/mpileup.cram.list") or error("$$opts{tmp}/mpileup.cram.list: $!"); + open(my $fh3,'>',"$$opts{tmp}/mpileup.bam.urllist") or error("$$opts{tmp}/mpileup.bam.urllist: $!"); + open(my $fh4,'>',"$$opts{tmp}/mpileup.cram.urllist") or error("$$opts{tmp}/mpileup.cram.urllist: $!"); + for my $file (@{$args{in}}) + { + print $fh1 "$$opts{path}/mpileup/mpileup.$file.bam\n"; + print $fh2 "$$opts{path}/mpileup/mpileup.$file.cram\n"; + print $fh3 "file://", abs_path("$$opts{path}/mpileup/mpileup.$file.bam"), "\n"; + print $fh4 "file://", abs_path("$$opts{path}/mpileup/mpileup.$file.cram"), "\n"; + } + close($fh1); + close($fh2); + close($fh3); + close($fh4); + } + + $args{args} =~ s/{PATH}/$$opts{path}/g; + for my $fmt ('bam','cram') + { + my @files = (); + for my $file (@{$args{in}}) { push @files, "$$opts{path}/mpileup/mpileup.$file.$fmt"; } + my $files = join(' ',@files); + my $grep_hdr = "grep -v ^##bcftools | grep -v ^##reference"; + test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools mpileup $args{args} -f $$opts{path}/mpileup/mpileup.ref.fa $files 2>/dev/null | $grep_hdr"); + test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools mpileup $args{args} -f $$opts{path}/mpileup/mpileup.ref.fa -Ob $files 2>/dev/null | $$opts{bin}/bcftools view | $grep_hdr"); + if ($args{test_list}) + { + test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools mpileup $args{args} -f $$opts{path}/mpileup/mpileup.ref.fa -b $$opts{tmp}/mpileup.$fmt.list --no-version 2>/dev/null | grep -v ^##reference"); + test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools mpileup $args{args} -f $$opts{path}/mpileup/mpileup.ref.fa -Ob -b $$opts{tmp}/mpileup.$fmt.urllist 2>/dev/null | $$opts{bin}/bcftools view | $grep_hdr"); + } + } +} + +sub test_csq +{ + my ($opts,%args) = @_; + $args{cmd} =~ s/{PATH}/$$opts{path}/g; + test_cmd($opts,%args,cmd=>"$$opts{bin}/bcftools csq $args{cmd} $$opts{path}/$args{in}.vcf | $$opts{bin}/test/csq/sort-csq | $$opts{bin}/bcftools query -f'%POS\\t%REF\\t%ALT\\t%EXP\\n%POS\\t%REF\\t%ALT\\t%BCSQ\\n\\n'"); +} +sub test_csq_real +{ + my ($opts,%args) = @_; + + my $dirname = "$$opts{path}/$args{in}"; + opendir(my $dh,$dirname) or error("opendir $dirname: $!"); + while (my $dir=readdir($dh)) + { + if ( !($dir=~/^E/) or !-d "$dirname/$dir" ) { next; } + my $gff = "$dirname/$dir/$dir.gff"; + my $ref = "$dirname/$dir/$dir.fa"; + opendir(my $tmp,"$dirname/$dir") or error("opendir: $dirname/$dir: $!"); + while (my $file=readdir($tmp)) + { + if ( !($file=~/\.vcf$/) ) { next; } + my $vcf = "$dirname/$dir/$file"; + my @nsmpl = `$$opts{bin}/bcftools query -l $vcf`; + my $cmd; + if ( !@nsmpl ) + { + $cmd = "$$opts{bin}/test/csq/sort-csq | $$opts{bin}/bcftools query -f'%POS\\t%REF\\t%ALT\\t%EXP\\n%POS\\t%REF\\t%ALT\\t%BCSQ\\n\\n'"; + } + else + { + $cmd = "$$opts{bin}/bcftools query -f'[%POS\\t%REF\\t%ALT\\t%TBCSQ\\n]\\n'"; + } + my $out = "$args{in}/$dir/$`.txt"; + my $outl = "$args{in}/$dir/$`.txt-l"; + test_cmd($opts,%args,out=>$out,cmd=>"$$opts{bin}/bcftools csq -f $ref -g $gff $vcf | $cmd"); + if ( -e "$$opts{path}/$outl" ) + { + test_cmd($opts,%args,out=>$outl,cmd=>"$$opts{bin}/bcftools csq -l -f $ref -g $gff $vcf | $cmd"); + } + } + closedir($tmp); + } + closedir($dh); +} + diff --git a/test/trio.out b/test/trio.out new file mode 100644 index 0000000..6c9f4a6 --- /dev/null +++ b/test/trio.out @@ -0,0 +1,7 @@ +# +# TRIO [2]Father [3]Mother [4]Child [5]nTested [6]nMendelian Errors [7]nSwitch [8]nSwitch (%) +TRIO HG00101 HG00102 HG00100 5 4 0 0.00 +TRIO HG00201 HG00202 HG00200 11 0 2 18.18 +# POP population or other grouping defined by an optional 7-th column of the PED file +# POP [2]Name [3]Number of trios [4]avgTested [5]avgMendelian Errors [6]avgSwitch [7]avgSwitch (%) +POP CEU 2 8 2 1 9.09 diff --git a/test/trio.ped b/test/trio.ped new file mode 100644 index 0000000..22fa049 --- /dev/null +++ b/test/trio.ped @@ -0,0 +1,6 @@ +HG00100 HG00100 HG00101 HG00102 2 0 CEU +HG00101 HG00101 0 0 1 0 CEU +HG00102 HG00102 0 0 2 0 CEU +HG00200 HG00200 HG00201 HG00202 2 0 CEU +HG00201 HG00201 0 0 1 0 CEU +HG00202 HG00202 0 0 2 0 CEU diff --git a/test/trio.vcf b/test/trio.vcf new file mode 100644 index 0000000..a9f36c0 --- /dev/null +++ b/test/trio.vcf @@ -0,0 +1,16 @@ +##fileformat=VCFv4.2 +##FILTER= +##contig= +##FORMAT= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT HG00100 HG00101 HG00102 HG00200 HG00201 HG00202 +20 302 . T TA 999 . . GT 0|1 1|0 1|1 0|1 1|0 1|1 +20 828 . T C 999 . . GT 0|1 1|1 1|1 0|1 1|0 1|1 +20 834 . G A 999 . . GT 0|1 0|1 1|1 1|0 1|0 1|1 +20 1665 . T C 999 . . GT 1|0 0|1 0|1 0|1 1|0 1|1 +20 1869 . A T 999 . . GT 0|1 0|0 1|1 0|1 1|0 1|1 +20 2041 . G A 999 . . GT 0|1 1|1 1|1 0|1 1|0 1|1 +20 2220 . G A 999 . . GT 0|1 1|0 1|1 0|1 1|0 1|1 +20 2564 . A G 999 . . GT 0|1 1|1 1|1 0|1 1|0 1|1 +20 3104 . C T 999 . . GT 0|0 0|0 0|1 0|1 1|0 1|1 +20 3587 . G A 999 . . GT 0|1 0|1 1|1 0|1 1|0 1|1 +20 3936 . A G 999 . . GT 0|1 1|1 1|1 0|1 1|0 1|1 diff --git a/test/vcf2sex.out b/test/vcf2sex.out new file mode 100644 index 0000000..894f6ef --- /dev/null +++ b/test/vcf2sex.out @@ -0,0 +1,2 @@ +MALE M +FEMALE F diff --git a/test/vcf2sex.vcf b/test/vcf2sex.vcf new file mode 100644 index 0000000..81d3f8d --- /dev/null +++ b/test/vcf2sex.vcf @@ -0,0 +1,24 @@ +##fileformat=VCFv4.2 +##FORMAT= +##contig= +##contig= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT MALE FEMALE +X 1 . C A . PASS . GT 1 0/1 +X 12000 . C A . PASS . GT 0 0/1 +X 24000 . C A . PASS . GT 1 0/1 +X 36000 . C A . PASS . GT 0 0/1 +X 48000 . C A . PASS . GT 1 0/1 +X 60000 . C A . PASS . GT 0 0/1 +X 100000 . C A . PASS . GT 0/1 0/1 +X 2699521 . C A . PASS . GT 0 0/1 +X 33145825 . C A . PASS . GT 1 0/1 +X 63592129 . C A . PASS . GT 1 0/1 +X 94038433 . C A . PASS . GT 0 0/1 +X 124484737 . C A . PASS . GT 0 0/1 +X 154931043 . C A . PASS . GT 0/1 0/1 +Y 1 . C A . PASS . GT 0 . +Y 11874713 . C A . PASS . GT 0 . +Y 23749426 . C A . PASS . GT 0 . +Y 35624139 . C A . PASS . GT 0 . +Y 47498852 . C A . PASS . GT 0 . +Y 59373565 . C A . PASS . GT 0 . diff --git a/test/view.1.out b/test/view.1.out new file mode 100644 index 0000000..15fc23f --- /dev/null +++ b/test/view.1.out @@ -0,0 +1,39 @@ +##fileformat=VCFv4.1 +##FILTER= +##reference=file:///seq/references/1000Genomes-NCBI37.fasta +##contig= +##contig= +##contig= +##contig= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FILTER= +##FILTER= +##FILTER= +##FILTER= +##FILTER= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA00002 +20 138125 rs2298108 G T 999 PASS DP4=174391,20849,82080,4950;DP=286107;Dels=0;FS=3200;HWE=0.199462;ICF=0.01858;MQ0=0;MQ=46;PV4=0,0,0,1;QD=17.22;AN=2;AC=1 GT:PL:DP:GQ 0/1:140,0,255:71:99 +20 138148 rs2298109 C T 999 PASS DP4=194136,45753,94945,14367;DP=356657;Dels=0;FS=3200;HWE=0.177865;ICF=0.0198;MQ0=0;MQ=47;PV4=0,0,0,1;QD=14.57;AN=2;AC=1 GT:PL:DP:GQ 0/1:192,0,255:82:99 +20 304568 . C T 999 PASS DP4=16413,4543,945,156;DP=43557;Dels=0;FS=3200;HWE=0.076855;ICF=0.0213;MQ0=0;MQ=50;PV4=0,0,0,1;QD=15.45;AN=2;AC=1 GT:PL:DP:GQ 0|1:192,0,255:13:99 +X 2942109 rs5939407 T C 999 PASS DP4=23273,27816,40128,48208;DP=146673;Dels=0;FS=43.639;HWE=0.622715;ICF=-0.01176;MQ0=1;MQ=46;PV4=0.65,1,0,1;QD=14.81;AN=1;AC=1 GT:PL:DP:GQ 1:255,0:33:99 +X 3048719 . T C 999 PASS DP4=13263,27466,40128,48208;DP=146673;Dels=0;FS=43.639;HWE=0.622715;ICF=-0.01176;MQ0=1;MQ=46;PV4=0.65,1,0,1;QD=14.81;AN=1;AC=1 GT:PL:DP:GQ 1:255,0:33:99 +Y 8657215 . 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GL -19.5,0,-25.5 -19.2,0,-25.5 -25.5,-23.5,0 +20 271225 . T TTTA,TA 999 StrandBias . GL -15.1,-5.3,-20.3,0,-5.2,-15.9 -25.5,0,-21.3,-25.5,-25.5,-25.5 -25.5,-25.5,-25.5,-25.5,0,-24.1 +20 304568 . C T 999 PASS . GL -9.5,0,-25.5 -19.2,0,-25.5 -25.5,-9.5,0 +20 326891 . A AC 999 PASS . GL -25.5,0,-13.2 -25.5,0,-13.9 .,.,. +X 2928329 rs62584840 C T 999 PASS . GL 0,-5.6 0,-8.1 -7.3,0,-1.9 +X 2933066 rs61746890 G C 999 PASS . GL 0,-25.5 0,-25.5 -25.5,-25.5,-25.5 +X 2942109 rs5939407 T C 999 PASS . GL 0,-25.5 -25.5,0 -25.5,-15.7,0 +X 3048719 . T C 999 PASS . GL 0,-25.5 -25.5,0 -25.5,0,-15.7 +Y 8657215 . C A 999 PASS . GL 0,-25.5 -25.5,0 . +Y 10011673 rs78249411 G A 999 MinAB . GL -12.6,-10.1 -9.5,0 . diff --git a/test/view.GP.vcf b/test/view.GP.vcf new file mode 100644 index 0000000..cf5beed --- /dev/null +++ b/test/view.GP.vcf @@ -0,0 +1,42 @@ +##fileformat=VCFv4.2 +##FILTER= +##contig= +##contig= +##FORMAT= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA12890 NA12891 NA12892 +22 16050159 . C T 68 . . GP 0.962,0.038,0 0,1,0 1,0,0 +22 16050252 . A T 85 . . GP 0.934,0.059,0.007 0,1,0 1,0,0 +22 16051249 . T C 32.1761 . . GP 0,1,0 1,0,0 1,0,0 +22 16051347 . G C 283 . . GP 0,0.443,0.557 0,1,0 1,0,0 +22 16051453 . A C 3.42882 . . GP 0.001,0.999,0 1,0,0 1,0,0 +22 16051497 . A G 362 . . GP 0,0.008,0.992 0,1,0 1,0,0 +22 16051968 . C A 136 . . GP 0.972,0.024,0.003 0,1,0 1,0,0 +22 16052167 . AAAACAAACAAACAAACAAACAAACAAACAAAC AAAACAAACAAACAAACAAACAAACAAACAAACAAACAAAC 217 . . GP 0.333,0.333,0.333 0,0,1 1,0,0 +22 16052169 . AACAAACA AACAAACAGACAAACA 241 . . GP 0.003,0.995,0.002 0,1,0 1,0,0 +22 16052180 . AAAC AAACCAACTAAC 221 . . GP 0.909,0.091,0 0,1,0 1,0,0 +22 16052239 . A G 172 . . GP 0.984,0.016,0 0,1,0 1,0,0 +22 16052513 . G C 153 . . GP 1,0,0 0,1,0 1,0,0 +22 16052618 . G A 124 . . GP 0.997,0.003,0 0,1,0 1,0,0 +22 16053659 . A C 352 . . GP 0,0.002,0.998 0,0,1 1,0,0 +22 16053791 . C A 287 . . GP 0,1,0 0,1,0 1,0,0 +22 16054454 . C T 14.2772 . . GP 0,0.76,0.24 1,0,0 1,0,0 +22 16054667 . C G 179 . . GP 0.998,0.002,0 0,1,0 1,0,0 +22 16054740 . A G 126 . . GP 0.994,0.006,0 0,1,0 1,0,0 +22 16055942 . C T 385 . . GP 0,0.008,0.992 0,0,1 1,0,0 +22 16056126 . G A 263 . . GP 0,0.969,0.031 0,1,0 1,0,0 +22 16056854 . G GA 17.3105 . . GP 0.996,0.004,0 0,1,0 1,0,0 +22 16057248 . G A 167 . . GP 0.988,0.012,0 0,1,0 1,0,0 +22 16057320 . G A 20.0168 . . GP 0,0.998,0.002 1,0,0 1,0,0 +22 16057417 . C T 16.3704 . . GP 0,1,0 1,0,0 1,0,0 +22 16058070 . A G 452 . . GP 0,0,1 0,0,1 0,0,1 +22 16058415 . A G 212 . . GP 0.997,0.003,0 0,0,1 1,0,0 +22 16058463 . C T 136 . . GP 0,0.666,0.334 1,0,0 1,0,0 +22 16058758 . C A 107 . . GP 0,0.166,0.834 1,0,0 1,0,0 +22 16058766 . G A 15.517 . . GP 0.999,0.001,0 0,0.201,0.799 1,0,0 +22 16058852 . A T 198 . . GP 0,0.112,0.888 0,0,1 1,0,0 +22 16058883 . A G 129 . . GP 0,0.334,0.666 0,0,1 1,0,0 +22 16059081 . A G 212 . . GP 0.984,0.016,0 0,0,1 1,0,0 +22 16059734 . C T 114 . . GP 0,0.038,0.962 1,0,0 1,0,0 +22 16059753 . A T 212 . . GP 0.998,0.002,0 0,0,1 1,0,0 +Y 16059973 . C A 195 . . GP 0.975,0.025 1,0 0,1 +Y 16060178 . G A 187 . . GP 0.969,0.031 0,1 0.5,0.5 diff --git a/test/view.GT.vcf b/test/view.GT.vcf new file mode 100644 index 0000000..2cf1725 --- /dev/null +++ b/test/view.GT.vcf @@ -0,0 +1,42 @@ +##fileformat=VCFv4.2 +##FILTER= +##contig= +##contig= +##FORMAT= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA12890 NA12891 NA12892 +22 16050159 . C T 68 . . GT 0/0 0/1 0/0 +22 16050252 . A T 85 . . GT 0/0 0/1 0/0 +22 16051249 . T C 32.1761 . . GT 0/1 0/0 0/0 +22 16051347 . G C 283 . . GT ./. 0/1 0/0 +22 16051453 . A C 3.42882 . . GT 0/1 0/0 0/0 +22 16051497 . A G 362 . . GT 1/1 0/1 0/0 +22 16051968 . C A 136 . . GT 0/0 0/1 0/0 +22 16052167 . AAAACAAACAAACAAACAAACAAACAAACAAAC AAAACAAACAAACAAACAAACAAACAAACAAACAAACAAAC 217 . . GT ./. 1/1 0/0 +22 16052169 . AACAAACA AACAAACAGACAAACA 241 . . GT 0/1 0/1 0/0 +22 16052180 . AAAC AAACCAACTAAC 221 . . GT 0/0 0/1 0/0 +22 16052239 . A G 172 . . GT 0/0 0/1 0/0 +22 16052513 . G C 153 . . GT 0/0 0/1 0/0 +22 16052618 . G A 124 . . GT 0/0 0/1 0/0 +22 16053659 . A C 352 . . GT 1/1 1/1 0/0 +22 16053791 . C A 287 . . GT 0/1 0/1 0/0 +22 16054454 . C T 14.2772 . . GT ./. 0/0 0/0 +22 16054667 . C G 179 . . GT 0/0 0/1 0/0 +22 16054740 . A G 126 . . GT 0/0 0/1 0/0 +22 16055942 . C T 385 . . GT 1/1 1/1 0/0 +22 16056126 . G A 263 . . GT 0/1 0/1 0/0 +22 16056854 . G GA 17.3105 . . GT 0/0 0/1 0/0 +22 16057248 . G A 167 . . GT 0/0 0/1 0/0 +22 16057320 . G A 20.0168 . . GT 0/1 0/0 0/0 +22 16057417 . C T 16.3704 . . GT 0/1 0/0 0/0 +22 16058070 . A G 452 . . GT 1/1 1/1 1/1 +22 16058415 . A G 212 . . GT 0/0 1/1 0/0 +22 16058463 . C T 136 . . GT ./. 0/0 0/0 +22 16058758 . C A 107 . . GT 1/1 0/0 0/0 +22 16058766 . G A 15.517 . . GT 0/0 ./. 0/0 +22 16058852 . A T 198 . . GT 1/1 1/1 0/0 +22 16058883 . A G 129 . . GT ./. 1/1 0/0 +22 16059081 . A G 212 . . GT 0/0 1/1 0/0 +22 16059734 . C T 114 . . GT 1/1 0/0 0/0 +22 16059753 . A T 212 . . GT 0/0 1/1 0/0 +Y 16059973 . C A 195 . . GT 0 0 1 +Y 16060178 . G A 187 . . GT 0 1 . diff --git a/test/view.GTisec.H.out b/test/view.GTisec.H.out new file mode 100644 index 0000000..5cf831b --- /dev/null +++ b/test/view.GTisec.H.out @@ -0,0 +1,20 @@ +# This file can be used as input to the subset plotting tools at: +# https://github.com/dlaehnemann/bankers2 +# Genotype intersections across samples: +@SMPS NA00003 NA00002 NA00001 +# Human readable output (-H) was requested. Subset intersection counts are therefore sorted by +# sample and repeated for each contained sample. For each sample, counts are in banker's +# sequence order regarding all other samples. +# [1] Number of shared non-ref genotypes [2] Samples sharing non-ref genotype (GT) +9 NA00003 +1 NA00003,NA00002 +0 NA00003,NA00001 +1 NA00003,NA00002,NA00001 +4 NA00002 +1 NA00002,NA00003 +8 NA00002,NA00001 +1 NA00002,NA00003,NA00001 +5 NA00001 +0 NA00001,NA00003 +8 NA00001,NA00002 +1 NA00001,NA00003,NA00002 diff --git a/test/view.GTisec.Hm.out b/test/view.GTisec.Hm.out new file mode 100644 index 0000000..e70f86b --- /dev/null +++ b/test/view.GTisec.Hm.out @@ -0,0 +1,25 @@ +# This file can be used as input to the subset plotting tools at: +# https://github.com/dlaehnemann/bankers2 +# Genotype intersections across samples: +@SMPS NA00003 NA00002 NA00001 +# The first line of each sample contains its count of missing genotypes, with a '-' appended +# to the sample name. +# Human readable output (-H) was requested. Subset intersection counts are therefore sorted by +# sample and repeated for each contained sample. For each sample, counts are in banker's +# sequence order regarding all other samples. +# [1] Number of shared non-ref genotypes [2] Samples sharing non-ref genotype (GT) +4 NA00003- +9 NA00003 +1 NA00003,NA00002 +0 NA00003,NA00001 +1 NA00003,NA00002,NA00001 +1 NA00002- +4 NA00002 +1 NA00002,NA00003 +8 NA00002,NA00001 +1 NA00002,NA00003,NA00001 +1 NA00001- +5 NA00001 +0 NA00001,NA00003 +8 NA00001,NA00002 +1 NA00001,NA00003,NA00002 diff --git a/test/view.GTisec.Hmv.out b/test/view.GTisec.Hmv.out new file mode 100644 index 0000000..e70f86b --- /dev/null +++ b/test/view.GTisec.Hmv.out @@ -0,0 +1,25 @@ +# This file can be used as input to the subset plotting tools at: +# https://github.com/dlaehnemann/bankers2 +# Genotype intersections across samples: +@SMPS NA00003 NA00002 NA00001 +# The first line of each sample contains its count of missing genotypes, with a '-' appended +# to the sample name. +# Human readable output (-H) was requested. Subset intersection counts are therefore sorted by +# sample and repeated for each contained sample. For each sample, counts are in banker's +# sequence order regarding all other samples. +# [1] Number of shared non-ref genotypes [2] Samples sharing non-ref genotype (GT) +4 NA00003- +9 NA00003 +1 NA00003,NA00002 +0 NA00003,NA00001 +1 NA00003,NA00002,NA00001 +1 NA00002- +4 NA00002 +1 NA00002,NA00003 +8 NA00002,NA00001 +1 NA00002,NA00003,NA00001 +1 NA00001- +5 NA00001 +0 NA00001,NA00003 +8 NA00001,NA00002 +1 NA00001,NA00003,NA00002 diff --git a/test/view.GTisec.Hv.out b/test/view.GTisec.Hv.out new file mode 100644 index 0000000..5cf831b --- /dev/null +++ b/test/view.GTisec.Hv.out @@ -0,0 +1,20 @@ +# This file can be used as input to the subset plotting tools at: +# https://github.com/dlaehnemann/bankers2 +# Genotype intersections across samples: +@SMPS NA00003 NA00002 NA00001 +# Human readable output (-H) was requested. Subset intersection counts are therefore sorted by +# sample and repeated for each contained sample. For each sample, counts are in banker's +# sequence order regarding all other samples. +# [1] Number of shared non-ref genotypes [2] Samples sharing non-ref genotype (GT) +9 NA00003 +1 NA00003,NA00002 +0 NA00003,NA00001 +1 NA00003,NA00002,NA00001 +4 NA00002 +1 NA00002,NA00003 +8 NA00002,NA00001 +1 NA00002,NA00003,NA00001 +5 NA00001 +0 NA00001,NA00003 +8 NA00001,NA00002 +1 NA00001,NA00003,NA00002 diff --git a/test/view.GTisec.m.out b/test/view.GTisec.m.out new file mode 100644 index 0000000..8d217a5 --- /dev/null +++ b/test/view.GTisec.m.out @@ -0,0 +1,20 @@ +# This file can be used as input to the subset plotting tools at: +# https://github.com/dlaehnemann/bankers2 +# Genotype intersections across samples: +@SMPS NA00003 NA00002 NA00001 +# The first 3 lines contain the counts for missing values of each sample in the order provided +# in the SMPS-line above. Intersection counts only start afterwards. +# Subset intersection counts are in global banker's sequence order. +# After exclusive sample counts in order of the SMPS-line, banker's sequence continues with: +# NA00003,NA00002 NA00003,NA00001 ... +# [1] Number of shared non-ref genotypes +4 +1 +1 +9 +4 +5 +1 +0 +8 +1 diff --git a/test/view.GTisec.mv.out b/test/view.GTisec.mv.out new file mode 100644 index 0000000..1772a3b --- /dev/null +++ b/test/view.GTisec.mv.out @@ -0,0 +1,20 @@ +# This file can be used as input to the subset plotting tools at: +# https://github.com/dlaehnemann/bankers2 +# Genotype intersections across samples: +@SMPS NA00003 NA00002 NA00001 +# The first 3 lines contain the counts for missing values of each sample in the order provided +# in the SMPS-line above. Intersection counts only start afterwards. +# Subset intersection counts are in global banker's sequence order. +# After exclusive sample counts in order of the SMPS-line, banker's sequence continues with: +# NA00003,NA00002 NA00003,NA00001 ... +# [1] Number of shared non-ref genotypes [2] Samples sharing non-ref genotype (GT) +4 NA00003- +1 NA00002- +1 NA00001- +9 NA00003 +4 NA00002 +5 NA00001 +1 NA00003,NA00002 +0 NA00003,NA00001 +8 NA00002,NA00001 +1 NA00003,NA00002,NA00001 diff --git a/test/view.GTisec.out b/test/view.GTisec.out new file mode 100644 index 0000000..2b2b0f6 --- /dev/null +++ b/test/view.GTisec.out @@ -0,0 +1,15 @@ +# This file can be used as input to the subset plotting tools at: +# https://github.com/dlaehnemann/bankers2 +# Genotype intersections across samples: +@SMPS NA00003 NA00002 NA00001 +# Subset intersection counts are in global banker's sequence order. +# After exclusive sample counts in order of the SMPS-line, banker's sequence continues with: +# NA00003,NA00002 NA00003,NA00001 ... +# [1] Number of shared non-ref genotypes +9 +4 +5 +1 +0 +8 +1 diff --git a/test/view.GTisec.v.out b/test/view.GTisec.v.out new file mode 100644 index 0000000..8ec3aa3 --- /dev/null +++ b/test/view.GTisec.v.out @@ -0,0 +1,15 @@ +# This file can be used as input to the subset plotting tools at: +# https://github.com/dlaehnemann/bankers2 +# Genotype intersections across samples: +@SMPS NA00003 NA00002 NA00001 +# Subset intersection counts are in global banker's sequence order. +# After exclusive sample counts in order of the SMPS-line, banker's sequence continues with: +# NA00003,NA00002 NA00003,NA00001 ... +# [1] Number of shared non-ref genotypes [2] Samples sharing non-ref genotype (GT) +9 NA00003 +4 NA00002 +5 NA00001 +1 NA00003,NA00002 +0 NA00003,NA00001 +8 NA00002,NA00001 +1 NA00003,NA00002,NA00001 diff --git a/test/view.GTsubset.NA1.out b/test/view.GTsubset.NA1.out new file mode 100644 index 0000000..84459c8 --- /dev/null +++ b/test/view.GTsubset.NA1.out @@ -0,0 +1,38 @@ +##fileformat=VCFv4.1 +##FILTER= +##reference=file:///seq/references/1000Genomes-NCBI37.fasta +##contig= +##contig= +##contig= +##contig= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FILTER= +##FILTER= +##FILTER= +##FILTER= +##FILTER= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA00001 NA00002 NA00003 +11 5464562 . C T 999 PASS DP=0 GT:PL:DP:GQ ./.:0,0,0:.:. ./.:0,0,0:.:. ./.:0,0,0:.:. +20 76962 rs6111385 T C 999 PASS DP4=110138,70822,421911,262673;DP=911531;Dels=0;FS=21.447;HWE=0.491006;ICF=-0.01062;MQ0=1;MQ=46;PV4=2.5e-09,0,0,1;QD=22.31 GT:PL:DP:GQ 0/1:255,0,255:193:99 1/1:255,255,0:211:99 1/1:255,255,0:182:99 +20 271225 . T TTTA,TA 999 StrandBias DP4=29281,42401,27887,29245;DP=272732;INDEL;IS=95,0.748031;MQ=47;PV4=0,1,0,1;QD=0.0948;AN=6;AC=2,2 GT:DP:GQ:PL 0/2:33:49:151,53,203,0,52,159 0/1:51:99:255,0,213,255,255,255 1/2:47:99:255,255,255,255,0,241 +X 2942109 rs5939407 T C 999 PASS DP4=23273,27816,40128,48208;DP=146673;Dels=0;FS=43.639;HWE=0.622715;ICF=-0.01176;MQ0=1;MQ=46;PV4=0.65,1,0,1;QD=14.81;AN=4;AC=3 GT:PL:DP:GQ 0:0,255:20:99 1:255,0:33:99 1/1:255,157,0:52:99 +X 3048719 . T C 999 PASS DP4=13263,27466,40128,48208;DP=146673;Dels=0;FS=43.639;HWE=0.622715;ICF=-0.01176;MQ0=1;MQ=46;PV4=0.65,1,0,1;QD=14.81;AN=4;AC=3 GT:PL:DP:GQ 0:0,255:20:99 1:255,0:33:99 0|1:255,0,157:52:99 +Y 8657215 . C A 999 PASS DP4=74915,114274,1948,2955;DP=195469;Dels=0;FS=3.181;MQ0=0;MQ=50;PV4=0.86,1,0,1;QD=33.77;AN=2;AC=1 GT:PL:DP:GQ 0:0,255:47:99 1:255,0:64:99 .:.:.:. diff --git a/test/view.GTsubset.NA1NA2.out b/test/view.GTsubset.NA1NA2.out new file mode 100644 index 0000000..1905348 --- /dev/null +++ b/test/view.GTsubset.NA1NA2.out @@ -0,0 +1,41 @@ +##fileformat=VCFv4.1 +##FILTER= +##reference=file:///seq/references/1000Genomes-NCBI37.fasta +##contig= +##contig= +##contig= +##contig= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FILTER= +##FILTER= +##FILTER= +##FILTER= +##FILTER= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA00001 NA00002 NA00003 +11 5464562 . C T 999 PASS DP=0 GT:PL:DP:GQ ./.:0,0,0:.:. ./.:0,0,0:.:. ./.:0,0,0:.:. +20 126310 . ACC A 999 StrandBias;EndDistBias DP4=125718,95950,113812,80890;DP=461867;HWE=0.24036;ICF=0.01738;INDEL;IS=374,0.937343;MQ=49;PV4=9e-30,1,0,3.8e-13;QD=0.0172;AN=6;AC=4 GT:DP:GQ:PL 0/1:117:99:255,0,132 0/1:111:99:255,0,139 1/1:78:99:255,213,0 +20 138125 rs2298108 G T 999 PASS DP4=174391,20849,82080,4950;DP=286107;Dels=0;FS=3200;HWE=0.199462;ICF=0.01858;MQ0=0;MQ=46;PV4=0,0,0,1;QD=17.22;AN=6;AC=4 GT:PL:DP:GQ 0/1:135,0,163:66:99 0/1:140,0,255:71:99 1/1:255,199,0:66:99 +20 138148 rs2298109 C T 999 PASS DP4=194136,45753,94945,14367;DP=356657;Dels=0;FS=3200;HWE=0.177865;ICF=0.0198;MQ0=0;MQ=47;PV4=0,0,0,1;QD=14.57;AN=6;AC=4 GT:PL:DP:GQ 0/1:195,0,255:87:99 0/1:192,0,255:82:99 1/1:255,235,0:78:99 +20 304568 . C T 999 PASS DP4=16413,4543,945,156;DP=43557;Dels=0;FS=3200;HWE=0.076855;ICF=0.0213;MQ0=0;MQ=50;PV4=0,0,0,1;QD=15.45;AN=6;AC=4 GT:PL:DP:GQ 0|1:95,0,255:90:99 0|1:192,0,255:13:99 1|1:255,95,0:60:99 +20 326891 . A AC 999 PASS DP4=125718,95950,113812,80890;DP=461867;HWE=0.24036;ICF=0.01738;INDEL;IS=374,0.937343;MQ=49;PV4=9e-30,1,0,3.8e-13;QD=0.0172;AN=4;AC=2 GT:DP:GQ:PL 0|1:117:99:255,0,132 0|1:111:99:255,0,139 ./.:.:.:.,.,. +X 2928329 rs62584840 C T 999 PASS DP4=302,9137,32,1329;DP=11020;Dels=0;FS=13.38;HWE=0.284332;ICF=0.0253;MQ0=0;MQ=49;PV4=0.094,0,0,1;QD=18.61;AN=4;AC=1 GT:PL:DP:GQ 0:0,56:2:73 0:0,81:3:98 0/1:73,0,19:4:30 +X 2933066 rs61746890 G C 999 PASS DP4=69865,100561,461,783;DP=173729;Dels=0;FS=10.833;MQ0=0;MQ=50;PV4=0.005,3.6e-14,0,1;QD=15.33;AN=4;AC=1 GT:PL:DP:GQ 0:0,255:39:99 0:0,255:37:99 0/1:255,255,255:62:99 +Y 10011673 rs78249411 G A 999 MinAB DP4=47351,30839,178796,279653;DP=550762;Dels=0;FS=41.028;MQ0=37362;MQ=26;PV4=0,0,0,1;QD=17.45;AN=2;AC=2 GT:PL:DP:GQ 1:126,101:146:37 1:95,0:130:99 .:.:.:. diff --git a/test/view.GTsubset.NA1NA2NA3.out b/test/view.GTsubset.NA1NA2NA3.out new file mode 100644 index 0000000..7fbb27e --- /dev/null +++ b/test/view.GTsubset.NA1NA2NA3.out @@ -0,0 +1,36 @@ +##fileformat=VCFv4.1 +##FILTER= +##reference=file:///seq/references/1000Genomes-NCBI37.fasta +##contig= +##contig= +##contig= +##contig= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FILTER= +##FILTER= +##FILTER= +##FILTER= +##FILTER= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA00001 NA00002 NA00003 +11 2343543 . A . 999 PASS DP=100223 GT:PL:DP:GQ 0/0:0,255,255:193:99 0/0:0,255,255:211:99 0/0:0,255,255:182:99 +11 5464562 . C T 999 PASS DP=0 GT:PL:DP:GQ ./.:0,0,0:.:. ./.:0,0,0:.:. ./.:0,0,0:.:. +20 326891 . A AC 999 PASS DP4=125718,95950,113812,80890;DP=461867;HWE=0.24036;ICF=0.01738;INDEL;IS=374,0.937343;MQ=49;PV4=9e-30,1,0,3.8e-13;QD=0.0172;AN=4;AC=2 GT:DP:GQ:PL 0|1:117:99:255,0,132 0|1:111:99:255,0,139 ./.:.:.:.,.,. +Y 10011673 rs78249411 G A 999 MinAB DP4=47351,30839,178796,279653;DP=550762;Dels=0;FS=41.028;MQ0=37362;MQ=26;PV4=0,0,0,1;QD=17.45;AN=2;AC=2 GT:PL:DP:GQ 1:126,101:146:37 1:95,0:130:99 .:.:.:. diff --git a/test/view.PL.vcf b/test/view.PL.vcf new file mode 100644 index 0000000..7d430ad --- /dev/null +++ b/test/view.PL.vcf @@ -0,0 +1,29 @@ +##fileformat=VCFv4.1 +##FILTER= +##reference=file:///seq/references/1000Genomes-NCBI37.fasta +##contig= +##contig= +##contig= +##contig= +##FILTER= +##FILTER= +##FILTER= +##FILTER= +##FILTER= +##FORMAT= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA00001 NA00002 NA00003 +11 2343543 . A . 999 PASS . PL 0,255,255 0,255,255 0,255,255 +11 5464562 . C T 999 PASS . PL 0,0,0 0,0,0 0,0,0 +20 76962 rs6111385 T C 999 PASS . PL 255,0,255 255,255,0 255,255,0 +20 126310 . ACC A 999 StrandBias;EndDistBias . PL 255,0,132 255,0,139 255,213,0 +20 138125 rs2298108 G T 999 PASS . PL 135,0,163 140,0,255 255,199,0 +20 138148 rs2298109 C T 999 PASS . PL 195,0,255 192,0,255 255,235,0 +20 271225 . T TTTA,TA 999 StrandBias . PL 151,53,203,0,52,159 255,0,213,255,255,255 255,255,255,255,0,241 +20 304568 . C T 999 PASS . PL 95,0,255 192,0,255 255,95,0 +20 326891 . A AC 999 PASS . PL 255,0,132 255,0,139 .,.,. +X 2928329 rs62584840 C T 999 PASS . PL 0,56 0,81 73,0,19 +X 2933066 rs61746890 G C 999 PASS . PL 0,255 0,255 255,255,255 +X 2942109 rs5939407 T C 999 PASS . PL 0,255 255,0 255,157,0 +X 3048719 . T C 999 PASS . PL 0,255 255,0 255,0,157 +Y 8657215 . C A 999 PASS . PL 0,255 255,0 . +Y 10011673 rs78249411 G A 999 MinAB . PL 126,101 95,0 . diff --git a/test/view.chrs.out b/test/view.chrs.out new file mode 100644 index 0000000..b6db11b --- /dev/null +++ b/test/view.chrs.out @@ -0,0 +1,81 @@ +##fileformat=VCFv4.1 +##FILTER= +##contig= +##contig= +##contig= +##FORMAT= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT AAA BBB +Pf3D7_01_v3 1 . A T . . . GT . . +Pf3D7_01_v3 2 . A G . . . GT . . +Pf3D7_01_v3 33 . T A . . . GT . . +Pf3D7_01_v3 36 . A G . . . GT . . +Pf3D7_01_v3 57 . C T . . . GT . . +Pf3D7_01_v3 61 . A T . . . GT . . +Pf3D7_01_v3 72 . T C,A . . . GT . . +Pf3D7_01_v3 73 . T A . . . GT . . +Pf3D7_01_v3 74 . A T,C . . . GT . . +Pf3D7_01_v3 84 . C T . . . GT . . +Pf3D7_01_v3 110 . T A . . . GT . . +Pf3D7_01_v3 111 . T A . . . GT . . +Pf3D7_01_v3 129 . T A . . . GT . . +Pf3D7_01_v3 146 . A C,T . . . GT . . +Pf3D7_01_v3 147 . A C,T . . . GT . . +Pf3D7_01_v3 152 . G T . . . GT . . +Pf3D7_01_v3 168 . T A . . . GT . . +Pf3D7_01_v3 169 . A G . . . GT . . +Pf3D7_01_v3 175 . A T . . . GT . . +Pf3D7_01_v3 195 . T A . . . GT . . +Pf3D7_01_v3 196 . A C . . . GT . . +Pf3D7_01_v3 199 . T C . . . GT . . +Pf3D7_01_v3 204 . C T . . . GT . . +Pf3D7_01_v3 213 . G A . . . GT . . +Pf3D7_01_v3 222 . A G . . . GT . . +Pf3D7_01_v3 223 . A G . . . GT . . +Pf3D7_01_v3 227 . T A . . . GT . . +Pf3D7_02_v3 90 . C T . . . GT . . +Pf3D7_02_v3 100 . T A . . . GT . . +Pf3D7_02_v3 111 . T A . . . GT . . +Pf3D7_02_v3 129 . T A . . . GT . . +Pf3D7_02_v3 146 . A C,T . . . GT . . +Pf3D7_02_v3 147 . A C,T . . . GT . . +Pf3D7_02_v3 152 . G T . . . GT . . +Pf3D7_02_v3 168 . T A . . . GT . . +Pf3D7_02_v3 169 . A G . . . GT . . +Pf3D7_02_v3 175 . A T . . . GT . . +Pf3D7_02_v3 195 . T A . . . GT . . +Pf3D7_02_v3 196 . A C . . . GT . . +Pf3D7_02_v3 199 . T C . . . GT . . +Pf3D7_02_v3 204 . C T . . . GT . . +Pf3D7_02_v3 213 . G A . . . GT . . +Pf3D7_02_v3 222 . A G . . . GT . . +Pf3D7_02_v3 223 . A G . . . GT . . +Pf3D7_02_v3 227 . T A . . . GT . . +Pf3D7_02_v3 235 . A G . . . GT . . +Pf3D7_03_v3 1 . A T . . . GT . . +Pf3D7_03_v3 2 . A G . . . GT . . +Pf3D7_03_v3 33 . T A . . . GT . . +Pf3D7_03_v3 36 . A G . . . GT . . +Pf3D7_03_v3 57 . C T . . . GT . . +Pf3D7_03_v3 61 . A T . . . GT . . +Pf3D7_03_v3 72 . T C,A . . . GT . . +Pf3D7_03_v3 73 . T A . . . GT . . +Pf3D7_03_v3 74 . A T,C . . . GT . . +Pf3D7_03_v3 84 . C T . . . GT . . +Pf3D7_03_v3 110 . T A . . . GT . . +Pf3D7_03_v3 111 . T A . . . GT . . +Pf3D7_03_v3 129 . T A . . . GT . . +Pf3D7_03_v3 146 . A C,T . . . GT . . +Pf3D7_03_v3 147 . A C,T . . . GT . . +Pf3D7_03_v3 152 . G T . . . GT . . +Pf3D7_03_v3 168 . T A . . . GT . . +Pf3D7_03_v3 169 . A G . . . GT . . +Pf3D7_03_v3 175 . A T . . . GT . . +Pf3D7_03_v3 195 . T A . . . GT . . +Pf3D7_03_v3 196 . A C . . . GT . . +Pf3D7_03_v3 199 . T C . . . GT . . +Pf3D7_03_v3 204 . C T . . . GT . . +Pf3D7_03_v3 213 . G A . . . GT . . +Pf3D7_03_v3 222 . A G . . . GT . . +Pf3D7_03_v3 223 . A G . . . GT . . +Pf3D7_03_v3 227 . T A . . . GT . . +Pf3D7_03_v3 235 . A G . . . GT . . diff --git a/test/view.chrs.tab b/test/view.chrs.tab new file mode 100644 index 0000000..90c0993 --- /dev/null +++ b/test/view.chrs.tab @@ -0,0 +1,74 @@ +Pf3D7_01_v3 1 +Pf3D7_01_v3 2 +Pf3D7_01_v3 33 +Pf3D7_01_v3 36 +Pf3D7_01_v3 57 +Pf3D7_01_v3 61 +Pf3D7_01_v3 72 +Pf3D7_01_v3 73 +Pf3D7_01_v3 74 +Pf3D7_01_v3 84 +Pf3D7_01_v3 110 +Pf3D7_01_v3 111 +Pf3D7_01_v3 129 +Pf3D7_01_v3 146 +Pf3D7_01_v3 147 +Pf3D7_01_v3 152 +Pf3D7_01_v3 168 +Pf3D7_01_v3 169 +Pf3D7_01_v3 175 +Pf3D7_01_v3 195 +Pf3D7_01_v3 196 +Pf3D7_01_v3 199 +Pf3D7_01_v3 204 +Pf3D7_01_v3 213 +Pf3D7_01_v3 222 +Pf3D7_01_v3 223 +Pf3D7_01_v3 227 +Pf3D7_02_v3 90 +Pf3D7_02_v3 100 +Pf3D7_02_v3 111 +Pf3D7_02_v3 129 +Pf3D7_02_v3 146 +Pf3D7_02_v3 147 +Pf3D7_02_v3 152 +Pf3D7_02_v3 168 +Pf3D7_02_v3 169 +Pf3D7_02_v3 175 +Pf3D7_02_v3 195 +Pf3D7_02_v3 196 +Pf3D7_02_v3 199 +Pf3D7_02_v3 204 +Pf3D7_02_v3 213 +Pf3D7_02_v3 222 +Pf3D7_02_v3 223 +Pf3D7_02_v3 227 +Pf3D7_02_v3 235 +Pf3D7_03_v3 1 +Pf3D7_03_v3 2 +Pf3D7_03_v3 33 +Pf3D7_03_v3 36 +Pf3D7_03_v3 57 +Pf3D7_03_v3 61 +Pf3D7_03_v3 72 +Pf3D7_03_v3 73 +Pf3D7_03_v3 74 +Pf3D7_03_v3 84 +Pf3D7_03_v3 110 +Pf3D7_03_v3 111 +Pf3D7_03_v3 129 +Pf3D7_03_v3 146 +Pf3D7_03_v3 147 +Pf3D7_03_v3 152 +Pf3D7_03_v3 168 +Pf3D7_03_v3 169 +Pf3D7_03_v3 175 +Pf3D7_03_v3 195 +Pf3D7_03_v3 196 +Pf3D7_03_v3 199 +Pf3D7_03_v3 204 +Pf3D7_03_v3 213 +Pf3D7_03_v3 222 +Pf3D7_03_v3 223 +Pf3D7_03_v3 227 +Pf3D7_03_v3 235 diff --git a/test/view.chrs.vcf b/test/view.chrs.vcf new file mode 100644 index 0000000..8fc5139 --- /dev/null +++ b/test/view.chrs.vcf @@ -0,0 +1,90 @@ +##fileformat=VCFv4.1 +##contig= +##contig= +##contig= +##FORMAT= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT AAA BBB +Pf3D7_01_v3 1 . A T . . . GT . . +Pf3D7_01_v3 2 . A G . . . GT . . +Pf3D7_01_v3 33 . T A . . . GT . . +Pf3D7_01_v3 36 . A G . . . GT . . +Pf3D7_01_v3 57 . C T . . . GT . . +Pf3D7_01_v3 61 . A T . . . GT . . +Pf3D7_01_v3 72 . T C,A . . . GT . . +Pf3D7_01_v3 73 . T A . . . GT . . +Pf3D7_01_v3 74 . A T,C . . . GT . . +Pf3D7_01_v3 84 . C T . . . GT . . +Pf3D7_01_v3 110 . T A . . . GT . . +Pf3D7_01_v3 111 . T A . . . GT . . +Pf3D7_01_v3 129 . T A . . . GT . . +Pf3D7_01_v3 146 . A C,T . . . GT . . +Pf3D7_01_v3 147 . A C,T . . . GT . . +Pf3D7_01_v3 152 . G T . . . GT . . +Pf3D7_01_v3 168 . T A . . . GT . . +Pf3D7_01_v3 169 . A G . . . GT . . +Pf3D7_01_v3 175 . A T . . . GT . . +Pf3D7_01_v3 195 . T A . . . GT . . +Pf3D7_01_v3 196 . A C . . . GT . . +Pf3D7_01_v3 199 . T C . . . GT . . +Pf3D7_01_v3 204 . C T . . . GT . . +Pf3D7_01_v3 213 . G A . . . GT . . +Pf3D7_01_v3 222 . A G . . . GT . . +Pf3D7_01_v3 223 . A G . . . GT . . +Pf3D7_01_v3 227 . T A . . . GT . . +Pf3D7_01_v3 235 . A G . . . GT . . +Pf3D7_02_v3 1 . A T . . . GT . . +Pf3D7_02_v3 2 . A G . . . GT . . +Pf3D7_02_v3 33 . T A . . . GT . . +Pf3D7_02_v3 36 . A G . . . GT . . +Pf3D7_02_v3 57 . C T . . . GT . . +Pf3D7_02_v3 61 . A T . . . GT . . +Pf3D7_02_v3 72 . T C,A . . . GT . . +Pf3D7_02_v3 73 . T A . . . GT . . +Pf3D7_02_v3 74 . A T,C . . . GT . . +Pf3D7_02_v3 90 . C T . . . GT . . +Pf3D7_02_v3 100 . T A . . . GT . . +Pf3D7_02_v3 111 . T A . . . GT . . +Pf3D7_02_v3 129 . T A . . . GT . . +Pf3D7_02_v3 146 . A C,T . . . GT . . +Pf3D7_02_v3 147 . A C,T . . . GT . . +Pf3D7_02_v3 152 . G T . . . GT . . +Pf3D7_02_v3 168 . T A . . . GT . . +Pf3D7_02_v3 169 . A G . . . GT . . +Pf3D7_02_v3 175 . A T . . . GT . . +Pf3D7_02_v3 195 . T A . . . GT . . +Pf3D7_02_v3 196 . A C . . . GT . . +Pf3D7_02_v3 199 . T C . . . GT . . +Pf3D7_02_v3 204 . C T . . . GT . . +Pf3D7_02_v3 213 . G A . . . GT . . +Pf3D7_02_v3 222 . A G . . . GT . . +Pf3D7_02_v3 223 . A G . . . GT . . +Pf3D7_02_v3 227 . T A . . . GT . . +Pf3D7_02_v3 235 . A G . . . GT . . +Pf3D7_03_v3 1 . A T . . . GT . . +Pf3D7_03_v3 2 . A G . . . GT . . +Pf3D7_03_v3 33 . T A . . . GT . . +Pf3D7_03_v3 36 . A G . . . GT . . +Pf3D7_03_v3 57 . C T . . . GT . . +Pf3D7_03_v3 61 . A T . . . GT . . +Pf3D7_03_v3 72 . T C,A . . . GT . . +Pf3D7_03_v3 73 . T A . . . GT . . +Pf3D7_03_v3 74 . A T,C . . . GT . . +Pf3D7_03_v3 84 . C T . . . GT . . +Pf3D7_03_v3 110 . T A . . . GT . . +Pf3D7_03_v3 111 . T A . . . GT . . +Pf3D7_03_v3 129 . T A . . . GT . . +Pf3D7_03_v3 146 . A C,T . . . GT . . +Pf3D7_03_v3 147 . A C,T . . . GT . . +Pf3D7_03_v3 152 . G T . . . GT . . +Pf3D7_03_v3 168 . T A . . . GT . . +Pf3D7_03_v3 169 . A G . . . GT . . +Pf3D7_03_v3 175 . A T . . . GT . . +Pf3D7_03_v3 195 . T A . . . GT . . +Pf3D7_03_v3 196 . A C . . . GT . . +Pf3D7_03_v3 199 . T C . . . GT . . +Pf3D7_03_v3 204 . C T . . . GT . . +Pf3D7_03_v3 213 . G A . . . GT . . +Pf3D7_03_v3 222 . A G . . . GT . . +Pf3D7_03_v3 223 . A G . . . GT . . +Pf3D7_03_v3 227 . T A . . . GT . . +Pf3D7_03_v3 235 . A G . . . GT . . diff --git a/test/view.dropgenotypes.noheader.out b/test/view.dropgenotypes.noheader.out new file mode 100644 index 0000000..7b5a3c8 --- /dev/null +++ b/test/view.dropgenotypes.noheader.out @@ -0,0 +1,5 @@ +20 14370 rs6054257 G A 29 PASS NS=3;DP=14 +20 17330 . T A 3 PASS NS=3;DP=11 +20 1110696 rs6040355 A G,T 67 PASS NS=2;DP=10 +20 1230237 . T . 47 PASS NS=3;DP=13 +20 1234567 microsat1 GTC G,GTCT 50 PASS NS=3;DP=9 diff --git a/test/view.dropgenotypes.out b/test/view.dropgenotypes.out new file mode 100644 index 0000000..8e983f6 --- /dev/null +++ b/test/view.dropgenotypes.out @@ -0,0 +1,12 @@ +##fileformat=VCFv4.2 +##FILTER= +##reference=file:///seq/references/1000GenomesPilot-NCBI36.fasta +##contig= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO +20 14370 rs6054257 G A 29 PASS NS=3;DP=14 +20 17330 . T A 3 PASS NS=3;DP=11 +20 1110696 rs6040355 A G,T 67 PASS NS=2;DP=10 +20 1230237 . T . 47 PASS NS=3;DP=13 +20 1234567 microsat1 GTC G,GTCT 50 PASS NS=3;DP=9 diff --git a/test/view.exclude.out b/test/view.exclude.out new file mode 100644 index 0000000..324c320 --- /dev/null +++ b/test/view.exclude.out @@ -0,0 +1,47 @@ +##fileformat=VCFv4.1 +##FILTER= +##reference=file:///seq/references/1000Genomes-NCBI37.fasta +##contig= +##contig= +##contig= +##contig= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FILTER= +##FILTER= +##FILTER= +##FILTER= +##FILTER= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA00001 NA00002 +11 2343543 . A . 999 PASS DP=100223;AN=4 GT:PL:DP:GQ 0/0:0,255,255:193:99 0/0:0,255,255:211:99 +11 5464562 . C T 999 PASS DP=0;AC=0;AN=0 GT:PL:DP:GQ ./.:0,0,0:.:. ./.:0,0,0:.:. +20 76962 rs6111385 T C 999 PASS DP4=110138,70822,421911,262673;DP=911531;Dels=0;FS=21.447;HWE=0.491006;ICF=-0.01062;MQ0=1;MQ=46;PV4=2.5e-09,0,0,1;QD=22.31;AC=3;AN=4 GT:PL:DP:GQ 0/1:255,0,255:193:99 1/1:255,255,0:211:99 +20 126310 . ACC A 999 StrandBias;EndDistBias DP4=125718,95950,113812,80890;DP=461867;HWE=0.24036;ICF=0.01738;INDEL;IS=374,0.937343;MQ=49;PV4=9e-30,1,0,3.8e-13;QD=0.0172;AN=4;AC=2 GT:DP:GQ:PL 0/1:117:99:255,0,132 0/1:111:99:255,0,139 +20 138125 rs2298108 G T 999 PASS DP4=174391,20849,82080,4950;DP=286107;Dels=0;FS=3200;HWE=0.199462;ICF=0.01858;MQ0=0;MQ=46;PV4=0,0,0,1;QD=17.22;AN=4;AC=2 GT:PL:DP:GQ 0/1:135,0,163:66:99 0/1:140,0,255:71:99 +20 138148 rs2298109 C T 999 PASS DP4=194136,45753,94945,14367;DP=356657;Dels=0;FS=3200;HWE=0.177865;ICF=0.0198;MQ0=0;MQ=47;PV4=0,0,0,1;QD=14.57;AN=4;AC=2 GT:PL:DP:GQ 0/1:195,0,255:87:99 0/1:192,0,255:82:99 +20 271225 . T TTTA,TA 999 StrandBias DP4=29281,42401,27887,29245;DP=272732;INDEL;IS=95,0.748031;MQ=47;PV4=0,1,0,1;QD=0.0948;AN=4;AC=1,1 GT:DP:GQ:PL 0/2:33:49:151,53,203,0,52,159 0/1:51:99:255,0,213,255,255,255 +20 304568 . C T 999 PASS DP4=16413,4543,945,156;DP=43557;Dels=0;FS=3200;HWE=0.076855;ICF=0.0213;MQ0=0;MQ=50;PV4=0,0,0,1;QD=15.45;AN=4;AC=2 GT:PL:DP:GQ 0|1:95,0,255:90:99 0|1:192,0,255:13:99 +20 326891 . A AC 999 PASS DP4=125718,95950,113812,80890;DP=461867;HWE=0.24036;ICF=0.01738;INDEL;IS=374,0.937343;MQ=49;PV4=9e-30,1,0,3.8e-13;QD=0.0172;AN=4;AC=2 GT:DP:GQ:PL 0|1:117:99:255,0,132 0|1:111:99:255,0,139 +X 2928329 rs62584840 C T 999 PASS DP4=302,9137,32,1329;DP=11020;Dels=0;FS=13.38;HWE=0.284332;ICF=0.0253;MQ0=0;MQ=49;PV4=0.094,0,0,1;QD=18.61;AN=2;AC=0 GT:PL:DP:GQ 0:0,56:2:73 0:0,81:3:98 +X 2933066 rs61746890 G C 999 PASS DP4=69865,100561,461,783;DP=173729;Dels=0;FS=10.833;MQ0=0;MQ=50;PV4=0.005,3.6e-14,0,1;QD=15.33;AN=2;AC=0 GT:PL:DP:GQ 0:0,255:39:99 0:0,255:37:99 +X 2942109 rs5939407 T C 999 PASS DP4=23273,27816,40128,48208;DP=146673;Dels=0;FS=43.639;HWE=0.622715;ICF=-0.01176;MQ0=1;MQ=46;PV4=0.65,1,0,1;QD=14.81;AN=2;AC=1 GT:PL:DP:GQ 0:0,255:20:99 1:255,0:33:99 +X 3048719 . T C 999 PASS DP4=13263,27466,40128,48208;DP=146673;Dels=0;FS=43.639;HWE=0.622715;ICF=-0.01176;MQ0=1;MQ=46;PV4=0.65,1,0,1;QD=14.81;AN=2;AC=1 GT:PL:DP:GQ 0:0,255:20:99 1:255,0:33:99 +Y 8657215 . C A 999 PASS DP4=74915,114274,1948,2955;DP=195469;Dels=0;FS=3.181;MQ0=0;MQ=50;PV4=0.86,1,0,1;QD=33.77;AN=2;AC=1 GT:PL:DP:GQ 0:0,255:47:99 1:255,0:64:99 +Y 10011673 rs78249411 G A 999 MinAB DP4=47351,30839,178796,279653;DP=550762;Dels=0;FS=41.028;MQ0=37362;MQ=26;PV4=0,0,0,1;QD=17.45;AN=2;AC=2 GT:PL:DP:GQ 1:126,101:146:37 1:95,0:130:99 diff --git a/test/view.filter.1.out b/test/view.filter.1.out new file mode 100644 index 0000000..9d00ad5 --- /dev/null +++ b/test/view.filter.1.out @@ -0,0 +1 @@ +1 3162007 . 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GAA G,GA 238 PASS DP=19;AN=4;AC=1,1;XRF=1e+06,2e+06,3e+06;XRI=1111,2222,3333;XRS=ABC,DEF,GHI;XAF=1e+06,2e+06;XAI=1111,2222;XAS=ABC,DEF;XGF=1e+06,2e+06,3e+06,4e+06,5e+06,6e+06;XGI=11,22,33,44,55,66;XGS=ABC,DEF,GHI,JKL,MNO,PQR;TXT=ABC,DEF,GHI GT:GQ:DP:STR 0/1:589:19:XX 0/2:1:1:YY +1 3162007 . TAGGG CAGGG,CAGGT 238 PASS AO=52101,113;CIGAR=1X4M,1X3M1X;TXT0=text GT:FGS:FGI:FGF:FAS:FAI:FAF:FRS:FRI:FRF 0/1:AAAAAA,BBBBB,CCCC,DDD,EE,F:1,2,3,4,5,6:0.1,0.02,0.003,0.0004,5e-05,6e-06:AAA,B:1,2:0.1,0.02:A,BB,CCC:1,2,3:0.1,0.02,0.003 .:AAAAAA,BBB,C:1,2,3:0.1,0.02,0.003:AAA,B:1,2:0.1,0.02:A,BB,CCC:1,2,3:0.1,0.02,0.003 diff --git a/test/view.filter.annovar.1.out b/test/view.filter.annovar.1.out new file mode 100644 index 0000000..e71068c --- /dev/null +++ b/test/view.filter.annovar.1.out @@ -0,0 +1,2 @@ +20 1230237 . T G 47 PASS NS=3;DP=13;AA=T;ANNOVAR_DATE=2015-06-17;Func.refGene=intronic;Gene.refGene=RAD21L1;GeneDetail.refGene=.;ExonicFunc.refGene=.;AAChange.refGene=.;Func.ensGene=intronic;Gene.ensGene=ENSG00000244588;GeneDetail.ensGene=.;ExonicFunc.ensGene=.;AAChange.ensGene=.;esp6500si_ea=.;esp6500si_all=.;1000g2012apr_eur=.;1000g2012apr_all=.;snp138=.;LJB2_SIFT=.;LJB2_PolyPhen2_HDIV=.;LJB2_PP2_HDIV_Pred=.;LJB2_PolyPhen2_HVAR=.;LJB2_PolyPhen2_HVAR_Pred=.;LJB2_LRT=.;LJB2_LRT_Pred=.;LJB2_MutationTaster=.;LJB2_MutationTaster_Pred=.;LJB_MutationAssessor=.;LJB_MutationAssessor_Pred=.;LJB2_FATHMM=.;LJB2_GERP++=.;LJB2_PhyloP=.;LJB2_SiPhy=.;ALLELE_END GT:GQ:DP:HQ 0|0:54:7:56,60 0|0:48:4:51,51 0/0:61:2:. +20 1230288 . T . 50 PASS NS=3;DP=13;AA=T;ANNOVAR_DATE=2015-06-17;Func.refGene=intronic;Gene.refGene=RAD21L1;GeneDetail.refGene=.;ExonicFunc.refGene=.;AAChange.refGene=.;Func.ensGene=intronic;Gene.ensGene=ENSG00000244588;GeneDetail.ensGene=.;ExonicFunc.ensGene=.;AAChange.ensGene=.;esp6500si_ea=.;esp6500si_all=.;1000g2012apr_eur=.;1000g2012apr_all=.;snp138=.;LJB2_SIFT=.;LJB2_PolyPhen2_HDIV=.;LJB2_PP2_HDIV_Pred=.;LJB2_PolyPhen2_HVAR=.;LJB2_PolyPhen2_HVAR_Pred=.;LJB2_LRT=.;LJB2_LRT_Pred=.;LJB2_MutationTaster=.;LJB2_MutationTaster_Pred=.;LJB_MutationAssessor=.;LJB_MutationAssessor_Pred=.;LJB2_FATHMM=.;LJB2_GERP++=.;LJB2_PhyloP=.;LJB2_SiPhy=.;ALLELE_END GT:GQ:DP:HQ 0|0:54:7:56,60 0|0:48:4:51,51 0/0:61:2:. diff --git a/test/view.filter.annovar.2.out b/test/view.filter.annovar.2.out new file mode 100644 index 0000000..6ac94a1 --- /dev/null +++ b/test/view.filter.annovar.2.out @@ -0,0 +1 @@ +16 50745926 rs2066844 C T 80 PASS NS=3;DP=14;AF=0.5;DB;H2;ANNOVAR_DATE=2015-06-17;Func.refGene=exonic;Gene.refGene=NOD2;GeneDetail.refGene=.;ExonicFunc.refGene=nonsynonymous_SNV;AAChange.refGene=NOD2:NM_001293557:exon3:c.C2023T:p.R675W,NOD2:NM_022162:exon4:c.C2104T:p.R702W;Func.ensGene=exonic;Gene.ensGene=ENSG00000167207;GeneDetail.ensGene=.;ExonicFunc.ensGene=nonsynonymous_SNV;AAChange.ensGene=ENSG00000167207:ENST00000300589:exon4:c.C2104T:p.R702W;esp6500si_ea=0.043488;esp6500si_all=0.031558;1000g2012apr_eur=0.05;1000g2012apr_all=0.02;snp138=rs2066844;LJB2_SIFT=0.010000;LJB2_PolyPhen2_HDIV=0.999;LJB2_PP2_HDIV_Pred=D;LJB2_PolyPhen2_HVAR=0.901;LJB2_PolyPhen2_HVAR_Pred=P;LJB2_LRT=0.993490;LJB2_LRT_Pred=N;LJB2_MutationTaster=0.291000;LJB2_MutationTaster_Pred=N;LJB_MutationAssessor=2.32;LJB_MutationAssessor_Pred=medium;LJB2_FATHMM=-0.5;LJB2_GERP++=3.66;LJB2_PhyloP=1.421000;LJB2_SiPhy=6.9139;ALLELE_END GT:GQ:DP:HQ 0|0:48:1:51,51 1|0:48:8:51,51 1/1:43:5:.,. diff --git a/test/view.filter.annovar.3.out b/test/view.filter.annovar.3.out new file mode 100644 index 0000000..6ac94a1 --- /dev/null +++ b/test/view.filter.annovar.3.out @@ -0,0 +1 @@ +16 50745926 rs2066844 C T 80 PASS NS=3;DP=14;AF=0.5;DB;H2;ANNOVAR_DATE=2015-06-17;Func.refGene=exonic;Gene.refGene=NOD2;GeneDetail.refGene=.;ExonicFunc.refGene=nonsynonymous_SNV;AAChange.refGene=NOD2:NM_001293557:exon3:c.C2023T:p.R675W,NOD2:NM_022162:exon4:c.C2104T:p.R702W;Func.ensGene=exonic;Gene.ensGene=ENSG00000167207;GeneDetail.ensGene=.;ExonicFunc.ensGene=nonsynonymous_SNV;AAChange.ensGene=ENSG00000167207:ENST00000300589:exon4:c.C2104T:p.R702W;esp6500si_ea=0.043488;esp6500si_all=0.031558;1000g2012apr_eur=0.05;1000g2012apr_all=0.02;snp138=rs2066844;LJB2_SIFT=0.010000;LJB2_PolyPhen2_HDIV=0.999;LJB2_PP2_HDIV_Pred=D;LJB2_PolyPhen2_HVAR=0.901;LJB2_PolyPhen2_HVAR_Pred=P;LJB2_LRT=0.993490;LJB2_LRT_Pred=N;LJB2_MutationTaster=0.291000;LJB2_MutationTaster_Pred=N;LJB_MutationAssessor=2.32;LJB_MutationAssessor_Pred=medium;LJB2_FATHMM=-0.5;LJB2_GERP++=3.66;LJB2_PhyloP=1.421000;LJB2_SiPhy=6.9139;ALLELE_END GT:GQ:DP:HQ 0|0:48:1:51,51 1|0:48:8:51,51 1/1:43:5:.,. diff --git a/test/view.filter.annovar.vcf b/test/view.filter.annovar.vcf new file mode 100644 index 0000000..c19aa25 --- /dev/null +++ b/test/view.filter.annovar.vcf @@ -0,0 +1,53 @@ +##fileformat=VCFv4.0 +##fileDate=20090805 +##source=myImputationProgramV3.1 +##reference=1000GenomesPilot-NCBI36 +##phasing=partial +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##FILTER= +##FILTER= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA00001 NA00002 NA00003 +16 50745926 rs2066844 C T 80 PASS NS=3;DP=14;AF=0.5;DB;H2;ANNOVAR_DATE=2015-06-17;Func.refGene=exonic;Gene.refGene=NOD2;GeneDetail.refGene=.;ExonicFunc.refGene=nonsynonymous_SNV;AAChange.refGene=NOD2:NM_001293557:exon3:c.C2023T:p.R675W,NOD2:NM_022162:exon4:c.C2104T:p.R702W;Func.ensGene=exonic;Gene.ensGene=ENSG00000167207;GeneDetail.ensGene=.;ExonicFunc.ensGene=nonsynonymous_SNV;AAChange.ensGene=ENSG00000167207:ENST00000300589:exon4:c.C2104T:p.R702W;esp6500si_ea=0.043488;esp6500si_all=0.031558;1000g2012apr_eur=0.05;1000g2012apr_all=0.02;snp138=rs2066844;LJB2_SIFT=0.010000;LJB2_PolyPhen2_HDIV=0.999;LJB2_PP2_HDIV_Pred=D;LJB2_PolyPhen2_HVAR=0.901;LJB2_PolyPhen2_HVAR_Pred=P;LJB2_LRT=0.993490;LJB2_LRT_Pred=N;LJB2_MutationTaster=0.291000;LJB2_MutationTaster_Pred=N;LJB_MutationAssessor=2.32;LJB_MutationAssessor_Pred=medium;LJB2_FATHMM=-0.5;LJB2_GERP++=3.66;LJB2_PhyloP=1.421000;LJB2_SiPhy=6.9139;ALLELE_END GT:GQ:DP:HQ 0|0:48:1:51,51 1|0:48:8:51,51 1/1:43:5:.,. +20 1230237 . T G 47 PASS NS=3;DP=13;AA=T;ANNOVAR_DATE=2015-06-17;Func.refGene=intronic;Gene.refGene=RAD21L1;GeneDetail.refGene=.;ExonicFunc.refGene=.;AAChange.refGene=.;Func.ensGene=intronic;Gene.ensGene=ENSG00000244588;GeneDetail.ensGene=.;ExonicFunc.ensGene=.;AAChange.ensGene=.;esp6500si_ea=.;esp6500si_all=.;1000g2012apr_eur=.;1000g2012apr_all=.;snp138=.;LJB2_SIFT=.;LJB2_PolyPhen2_HDIV=.;LJB2_PP2_HDIV_Pred=.;LJB2_PolyPhen2_HVAR=.;LJB2_PolyPhen2_HVAR_Pred=.;LJB2_LRT=.;LJB2_LRT_Pred=.;LJB2_MutationTaster=.;LJB2_MutationTaster_Pred=.;LJB_MutationAssessor=.;LJB_MutationAssessor_Pred=.;LJB2_FATHMM=.;LJB2_GERP++=.;LJB2_PhyloP=.;LJB2_SiPhy=.;ALLELE_END GT:GQ:DP:HQ 0|0:54:7:56,60 0|0:48:4:51,51 0/0:61:2 +20 1230288 . T . 50 PASS NS=3;DP=13;AA=T;ANNOVAR_DATE=2015-06-17;Func.refGene=intronic;Gene.refGene=RAD21L1;GeneDetail.refGene=.;ExonicFunc.refGene=.;AAChange.refGene=.;Func.ensGene=intronic;Gene.ensGene=ENSG00000244588;GeneDetail.ensGene=.;ExonicFunc.ensGene=.;AAChange.ensGene=.;esp6500si_ea=.;esp6500si_all=.;1000g2012apr_eur=.;1000g2012apr_all=.;snp138=.;LJB2_SIFT=.;LJB2_PolyPhen2_HDIV=.;LJB2_PP2_HDIV_Pred=.;LJB2_PolyPhen2_HVAR=.;LJB2_PolyPhen2_HVAR_Pred=.;LJB2_LRT=.;LJB2_LRT_Pred=.;LJB2_MutationTaster=.;LJB2_MutationTaster_Pred=.;LJB_MutationAssessor=.;LJB_MutationAssessor_Pred=.;LJB2_FATHMM=.;LJB2_GERP++=.;LJB2_PhyloP=.;LJB2_SiPhy=.;ALLELE_END GT:GQ:DP:HQ 0|0:54:7:56,60 0|0:48:4:51,51 0/0:61:2 diff --git a/test/view.filter.vcf b/test/view.filter.vcf new file mode 100644 index 0000000..df6bc7b --- /dev/null +++ b/test/view.filter.vcf @@ -0,0 +1,42 @@ +##fileformat=VCFv4.2 +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##SAMPLE=\") quoting nonsense where double brackets would do just fine",softwareName=,softwareVer=<119,65>,softwareParam=<.>,MetadataResource=http://somewhere.com/path> +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FILTER= +##contig= +##contig= +##contig= +##contig= +##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B +1 3162006 . GAA G,GA 238 PASS DP=19;AN=4;AC=1,1;XRF=1e6,2e6,3e6;XRI=1111,2222,3333;XRS=ABC,DEF,GHI;XAF=1e6,2e6;XAI=1111,2222;XAS=ABC,DEF;XGF=1e6,2e6,3e6,4e6,5e6,6e6;XGI=11,22,33,44,55,66;XGS=ABC,DEF,GHI,JKL,MNO,PQR;TXT=ABC,DEF,GHI GT:GQ:DP:STR 0/1:589:19:XX 0/2:1:1:YY +1 3162007 . TAGGG CAGGG,CAGGT 238 PASS AO=52101,113;CIGAR=1X4M,1X3M1X;TXT0=text GT:FGS:FGI:FGF:FAS:FAI:FAF:FRS:FRI:FRF 0/1:AAAAAA,BBBBB,CCCC,DDD,EE,F:1,2,3,4,5,6:1e-1,2e-2,3e-3,4e-4,5e-5,6e-6:AAA,B:1,2:1e-1,2e-2:A,BB,CCC:1,2,3:1e-1,2e-2,3e-3 2:AAAAAA,BBB,C:1,2,3:1e-1,2e-2,3e-3:AAA,B:1,2:1e-1,2e-2:A,BB,CCC:1,2,3:1e-1,2e-2,3e-3 diff --git a/test/view.minmaxac.1.out b/test/view.minmaxac.1.out new file mode 100644 index 0000000..e76c09f --- /dev/null +++ b/test/view.minmaxac.1.out @@ -0,0 +1 @@ +20 1234567 . A G,C,T 50 PASS NS=3;DP=9;AC=3,1,1;AN=8 GT:GQ:DP:TS 0/1:35:4:A,. 0/2:17:2:. 1/1:40:3:. 0/3:17:2:. diff --git a/test/view.minmaxac.2.out b/test/view.minmaxac.2.out new file mode 100644 index 0000000..eccc02a --- /dev/null +++ b/test/view.minmaxac.2.out @@ -0,0 +1 @@ +20 1234568 . A G,C,T 50 PASS NS=3;DP=9;AC=2,2,2;AN=8 GT:GQ:DP:TS 0/1:35:4:A,. 2/2:17:2:. 3/3:40:3:. 0/1:17:2:. diff --git a/test/view.minmaxac.vcf b/test/view.minmaxac.vcf new file mode 100644 index 0000000..0010d2f --- /dev/null +++ b/test/view.minmaxac.vcf @@ -0,0 +1,13 @@ +##fileformat=VCFv4.2 +##reference=file:///seq/references/1000GenomesPilot-NCBI36.fasta +##contig= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA00001 NA00002 NA00003 NA00004 +20 1234567 . A G,C,T 50 PASS NS=3;DP=9 GT:GQ:DP:TS 0/1:35:4:A,. 0/2:17:2 1/1:40:3 0/3:17:2 +20 1234568 . A G,C,T 50 PASS NS=3;DP=9 GT:GQ:DP:TS 0/1:35:4:A,. 2/2:17:2 3/3:40:3 0/1:17:2 diff --git a/test/view.omitgenotypes.out b/test/view.omitgenotypes.out new file mode 100644 index 0000000..1b3dc20 --- /dev/null +++ b/test/view.omitgenotypes.out @@ -0,0 +1,17 @@ +##fileformat=VCFv4.2 +##FILTER= +##reference=file:///seq/references/1000GenomesPilot-NCBI36.fasta +##contig= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA00001 NA00002 NA00003 +20 14370 rs6054257 G A 29 PASS NS=3;DP=14 GT:GQ:DP:HQ 0|0:48:1:51,51 1|0:48:8:51,51 1/1:43:5:.,. +20 17330 . T A 3 PASS NS=3;DP=11 GT:GQ:DP:HQ ./.:.:.:.,. ./.:.:.:.,. ./.:.:.:.,. +20 1110696 rs6040355 A G,T 67 PASS NS=2;DP=10 GT:GQ:DP:HQ:TS ./.:.:.:.:. ./.:.:.:.:. ./.:.:.:.:. +20 1230237 . T . 47 PASS NS=3;DP=13 GT:GQ:DP:HQ:TS .:.:.:.:. .:.:.:.:. .:.:.:.:. +20 1234567 microsat1 GTC G,GTCT 50 PASS NS=3;DP=9 GT:GQ:DP:TS 0/1:35:4:A,. 0/2:17:2:. 1/1:40:3:. diff --git a/test/view.omitgenotypes.vcf b/test/view.omitgenotypes.vcf new file mode 100644 index 0000000..a140f67 --- /dev/null +++ b/test/view.omitgenotypes.vcf @@ -0,0 +1,16 @@ +##fileformat=VCFv4.2 +##reference=file:///seq/references/1000GenomesPilot-NCBI36.fasta +##contig= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA00001 NA00002 NA00003 +20 14370 rs6054257 G A 29 PASS NS=3;DP=14 GT:GQ:DP:HQ 0|0:48:1:51,51 1|0:48:8:51,51 1/1:43:5:.,. +20 17330 . T A 3 PASS NS=3;DP=11 GT:GQ:DP:HQ ./.:.:.:.,. ./.:.:.:.,. ./.:.:.:.,. +20 1110696 rs6040355 A G,T 67 PASS NS=2;DP=10 GT:GQ:DP:HQ:TS ./. ./. ./. +20 1230237 . T . 47 PASS NS=3;DP=13 GT:GQ:DP:HQ:TS . . . +20 1234567 microsat1 GTC G,GTCT 50 PASS NS=3;DP=9 GT:GQ:DP:TS 0/1:35:4:A,. 0/2:17:2 1/1:40:3 diff --git a/test/view.vcf b/test/view.vcf new file mode 100644 index 0000000..9e6c2fd --- /dev/null +++ b/test/view.vcf @@ -0,0 +1,46 @@ +##fileformat=VCFv4.1 +##reference=file:///seq/references/1000Genomes-NCBI37.fasta +##contig= +##contig= +##contig= +##contig= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FILTER= +##FILTER= +##FILTER= +##FILTER= +##FILTER= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT NA00001 NA00002 NA00003 +11 2343543 . A . 999 PASS DP=100223 GT:PL:DP:GQ 0/0:0,255,255:193:99 0/0:0,255,255:211:99 0/0:0,255,255:182:99 +11 5464562 . C T 999 PASS DP=0 GT:PL:DP:GQ ./.:0,0,0:.:. ./.:0,0,0:.:. ./.:0,0,0:.:. +20 76962 rs6111385 T C 999 PASS DP4=110138,70822,421911,262673;DP=911531;Dels=0;FS=21.447;HWE=0.491006;ICF=-0.01062;MQ0=1;MQ=46;PV4=2.5e-09,0,0,1;QD=22.31 GT:PL:DP:GQ 0/1:255,0,255:193:99 1/1:255,255,0:211:99 1/1:255,255,0:182:99 +20 126310 . ACC A 999 StrandBias;EndDistBias DP4=125718,95950,113812,80890;DP=461867;HWE=0.24036;ICF=0.01738;INDEL;IS=374,0.937343;MQ=49;PV4=9e-30,1,0,3.8e-13;QD=0.0172;AN=6;AC=4 GT:DP:GQ:PL 0/1:117:99:255,0,132 0/1:111:99:255,0,139 1/1:78:99:255,213,0 +20 138125 rs2298108 G T 999 PASS DP4=174391,20849,82080,4950;DP=286107;Dels=0;FS=3200;HWE=0.199462;ICF=0.01858;MQ0=0;MQ=46;PV4=0,0,0,1;QD=17.22;AN=6;AC=4 GT:PL:DP:GQ 0/1:135,0,163:66:99 0/1:140,0,255:71:99 1/1:255,199,0:66:99 +20 138148 rs2298109 C T 999 PASS DP4=194136,45753,94945,14367;DP=356657;Dels=0;FS=3200;HWE=0.177865;ICF=0.0198;MQ0=0;MQ=47;PV4=0,0,0,1;QD=14.57;AN=6;AC=4 GT:PL:DP:GQ 0/1:195,0,255:87:99 0/1:192,0,255:82:99 1/1:255,235,0:78:99 +20 271225 . T TTTA,TA 999 StrandBias DP4=29281,42401,27887,29245;DP=272732;INDEL;IS=95,0.748031;MQ=47;PV4=0,1,0,1;QD=0.0948;AN=6;AC=2,2 GT:DP:GQ:PL 0/2:33:49:151,53,203,0,52,159 0/1:51:99:255,0,213,255,255,255 1/2:47:99:255,255,255,255,0,241 +20 304568 . C T 999 PASS DP4=16413,4543,945,156;DP=43557;Dels=0;FS=3200;HWE=0.076855;ICF=0.0213;MQ0=0;MQ=50;PV4=0,0,0,1;QD=15.45;AN=6;AC=4 GT:PL:DP:GQ 0|1:95,0,255:90:99 0|1:192,0,255:13:99 1|1:255,95,0:60:99 +20 326891 . A AC 999 PASS DP4=125718,95950,113812,80890;DP=461867;HWE=0.24036;ICF=0.01738;INDEL;IS=374,0.937343;MQ=49;PV4=9e-30,1,0,3.8e-13;QD=0.0172;AN=4;AC=2 GT:DP:GQ:PL 0|1:117:99:255,0,132 0|1:111:99:255,0,139 ./.:.:.:.,.,. +X 2928329 rs62584840 C T 999 PASS DP4=302,9137,32,1329;DP=11020;Dels=0;FS=13.38;HWE=0.284332;ICF=0.0253;MQ0=0;MQ=49;PV4=0.094,0,0,1;QD=18.61;AN=4;AC=1 GT:PL:DP:GQ 0:0,56:2:73 0:0,81:3:98 0/1:73,0,19:4:30 +X 2933066 rs61746890 G C 999 PASS DP4=69865,100561,461,783;DP=173729;Dels=0;FS=10.833;MQ0=0;MQ=50;PV4=0.005,3.6e-14,0,1;QD=15.33;AN=4;AC=1 GT:PL:DP:GQ 0:0,255:39:99 0:0,255:37:99 0/1:255,255,255:62:99 +X 2942109 rs5939407 T C 999 PASS DP4=23273,27816,40128,48208;DP=146673;Dels=0;FS=43.639;HWE=0.622715;ICF=-0.01176;MQ0=1;MQ=46;PV4=0.65,1,0,1;QD=14.81;AN=4;AC=3 GT:PL:DP:GQ 0:0,255:20:99 1:255,0:33:99 1/1:255,157,0:52:99 +X 3048719 . T C 999 PASS DP4=13263,27466,40128,48208;DP=146673;Dels=0;FS=43.639;HWE=0.622715;ICF=-0.01176;MQ0=1;MQ=46;PV4=0.65,1,0,1;QD=14.81;AN=4;AC=3 GT:PL:DP:GQ 0:0,255:20:99 1:255,0:33:99 0|1:255,0,157:52:99 +Y 8657215 . C A 999 PASS DP4=74915,114274,1948,2955;DP=195469;Dels=0;FS=3.181;MQ0=0;MQ=50;PV4=0.86,1,0,1;QD=33.77;AN=2;AC=1 GT:PL:DP:GQ 0:0,255:47:99 1:255,0:64:99 . +Y 10011673 rs78249411 G A 999 MinAB DP4=47351,30839,178796,279653;DP=550762;Dels=0;FS=41.028;MQ0=37362;MQ=26;PV4=0,0,0,1;QD=17.45;AN=2;AC=2 GT:PL:DP:GQ 1:126,101:146:37 1:95,0:130:99 . diff --git a/test/view.vectors.2.vcf b/test/view.vectors.2.vcf new file mode 100644 index 0000000..bcadb72 --- /dev/null +++ b/test/view.vectors.2.vcf @@ -0,0 +1,25 @@ +##fileformat=VCFv4.2 +##contig= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B +1 10 . A C,T 999 PASS IAF=.;IRF=.;IGF=.;IAI=.;IRI=.;IGI=.;IAS=.,.;IRS=.,.,.;IGS=.,.,.,.,.,. GT:FAF:FRF:FGF:FAI:FRI:FGI:FAS:FRS:FGS 0/1:.:.:.:.:.:.:.,.:.,.,.:.,.,.,.,.,. 0/0:.:.:.:.:.:.:.,.:.,.,.:.,.,.,.,.,. +1 20 . A T,G 999 PASS IAF=.;IRF=.;IGF=.;IAI=.;IRI=.;IGI=.;IAS=.,.;IRS=.,.,.;IGS=.,.,.,.,.,. GT:FAF:FRF:FGF:FAI:FRI:FGI:FAS:FRS:FGS 0/1 0/0:. +1 30 . G A,C 999 PASS IAF=.;IRF=.;IGF=.;IAI=.;IRI=.;IGI=.;IAS=.;IRS=.;IGS=. GT:FAF:FRF:FGF:FAI:FRI:FGI:FAS:FRS:FGS 0/1:.:.:.:.:.:.:.:.:. 0/0:.:.:.:.:.:.:.:.:. diff --git a/test/view.vectors.A.out b/test/view.vectors.A.out new file mode 100644 index 0000000..c8be333 --- /dev/null +++ b/test/view.vectors.A.out @@ -0,0 +1,56 @@ +##fileformat=VCFv4.2 +##FILTER= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##SAMPLE=\") quoting nonsense where double brackets would do just fine",softwareName=,softwareVer=<119,65>,softwareParam=<.>,MetadataResource=http://somewhere.com/path> +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FILTER= +##contig= +##contig= +##contig= +##contig= +##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A +1 3162006 . GAA G 238 PASS DP=19;AN=2;AC=1;XRF=1e+06,2e+06;XRI=1111,2222;XRS=ABC,DEF;XAF=1e+06;XAI=1111;XAS=ABC;XGF=1e+06,2e+06,3e+06;XGI=11,22,33;XGS=ABC,DEF,GHI;TXT=ABC,DEF,GHI GT:GQ:DP 0/1:589:19 +1 3162007 . TAGGG CAGGG 238 PASS AO=52101;CIGAR=1X4M;AC=1;AN=2 GT:FGS:FGI:FGF:FAS:FAI:FAF:FRS:FRI:FRF 0/1:AAAAAA,BBBBB,CCCC:1,2,3:0.1,0.02,0.003:AAA:1:0.1:A,BB:1,2:0.1,0.02 +1 3162008 . TAGGG CAGGG 238 PASS IA8=10,.;IA16=1000,.;IA32=100000,.;IAF=0.003,.;CIGAR=1X4M;AC=1;AN=2 GT:F8:F16:F32:FF 0/1:10:1000:100000:0.003 +1 3162009 . TAGGG CAGGG 238 PASS IA8=.;IA16=.;IA32=.;IAF=.;CIGAR=1X4M;AC=1;AN=2 GT:F8:F16:F32:FF 0/1:10:1000:100000:0.003 +1 3162010 . TAGGG CAGGG 238 PASS I8=.;I16=.;I32=.;IF=.;CIGAR=1X4M;AC=1;AN=2 GT:F8:F16:F32:FF 0/1:10:1000:100000:0.003 diff --git a/test/view.vectors.B.out b/test/view.vectors.B.out new file mode 100644 index 0000000..6083f67 --- /dev/null +++ b/test/view.vectors.B.out @@ -0,0 +1,56 @@ +##fileformat=VCFv4.2 +##FILTER= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##SAMPLE=\") quoting nonsense where double brackets would do just fine",softwareName=,softwareVer=<119,65>,softwareParam=<.>,MetadataResource=http://somewhere.com/path> +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FILTER= +##contig= +##contig= +##contig= +##contig= +##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT B +1 3162006 . GAA GA 238 PASS DP=19;AN=2;AC=1;XRF=1e+06,3e+06;XRI=1111,3333;XRS=ABC,GHI;XAF=2e+06;XAI=2222;XAS=DEF;XGF=1e+06,4e+06,6e+06;XGI=11,44,66;XGS=ABC,JKL,PQR;TXT=ABC,DEF,GHI GT:GQ:DP 0/1:1:1 +1 3162007 . TAGGG CAGGT 238 PASS AO=113;CIGAR=1X3M1X;AC=1;AN=1 GT:FGS:FGI:FGF:FAS:FAI:FAF:FRS:FRI:FRF 1:AAAAAA,C:1,3:0.1,0.003:B:2:0.02:A,CCC:1,3:0.1,0.003 +1 3162008 . TAGGG CAGGT 238 PASS IA8=10,.;IA16=1000,.;IA32=100000,.;IAF=0.003,.;CIGAR=1X3M1X;AC=1;AN=1 GT:F8:F16:F32:FF 1:.:.:.:. +1 3162009 . TAGGG CAGGT 238 PASS IA8=.;IA16=.;IA32=.;IAF=.;CIGAR=1X3M1X;AC=1;AN=1 GT:F8:F16:F32:FF 1:.:.:.:. +1 3162010 . TAGGG CAGGT 238 PASS I8=.;I16=.;I32=.;IF=.;CIGAR=1X3M1X;AC=1;AN=1 GT:F8:F16:F32:FF 1:.:.:.:. diff --git a/test/view.vectors.C.out b/test/view.vectors.C.out new file mode 100644 index 0000000..9f54bd8 --- /dev/null +++ b/test/view.vectors.C.out @@ -0,0 +1,28 @@ +##fileformat=VCFv4.2 +##FILTER= +##contig= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##INFO= +##INFO= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A +1 10 . A C 999 PASS IAF=.;IRF=.;IGF=.;IAI=.;IRI=.;IGI=.;IAS=.;IRS=.,.;IGS=.,.,.;AC=1;AN=2 GT:FAF:FRF:FGF:FAI:FRI:FGI:FAS:FRS:FGS 0/1:.:.:.:.:.:.:.:.,.:.,.,. +1 20 . A T 999 PASS IAF=.;IRF=.;IGF=.;IAI=.;IRI=.;IGI=.;IAS=.;IRS=.,.;IGS=.,.,.;AC=1;AN=2 GT:FAF:FRF:FGF:FAI:FRI:FGI:FAS:FRS:FGS 0/1:.:.:.:.:.:.:.:.:. +1 30 . G A 999 PASS IAF=.;IRF=.;IGF=.;IAI=.;IRI=.;IGI=.;IAS=.;IRS=.;IGS=.;AC=1;AN=2 GT:FAF:FRF:FGF:FAI:FRI:FGI:FAS:FRS 0/1:.:.:.:.:.:.:.:. diff --git a/test/view.vectors.vcf b/test/view.vectors.vcf new file mode 100644 index 0000000..903e57b --- /dev/null +++ b/test/view.vectors.vcf @@ -0,0 +1,55 @@ +##fileformat=VCFv4.2 +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##SAMPLE=\") quoting nonsense where double brackets would do just fine",softwareName=,softwareVer=<119,65>,softwareParam=<.>,MetadataResource=http://somewhere.com/path> +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +##FILTER= +##contig= +##contig= +##contig= +##contig= +##reference=file:///lustre/scratch105/projects/g1k/ref/main_project/human_g1k_v37.fasta +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##INFO= +##FORMAT= +##FORMAT= +##FORMAT= +##FORMAT= +#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT A B +1 3162006 . GAA G,GA 238 PASS DP=19;AN=4;AC=1,1;XRF=1e6,2e6,3e6;XRI=1111,2222,3333;XRS=ABC,DEF,GHI;XAF=1e6,2e6;XAI=1111,2222;XAS=ABC,DEF;XGF=1e6,2e6,3e6,4e6,5e6,6e6;XGI=11,22,33,44,55,66;XGS=ABC,DEF,GHI,JKL,MNO,PQR;TXT=ABC,DEF,GHI GT:GQ:DP 0/1:589:19 0/2:1:1 +1 3162007 . TAGGG CAGGG,CAGGT 238 PASS AO=52101,113;CIGAR=1X4M,1X3M1X GT:FGS:FGI:FGF:FAS:FAI:FAF:FRS:FRI:FRF 0/1:AAAAAA,BBBBB,CCCC,DDD,EE,F:1,2,3,4,5,6:1e-1,2e-2,3e-3,4e-4,5e-5,6e-6:AAA,B:1,2:1e-1,2e-2:A,BB,CCC:1,2,3:1e-1,2e-2,3e-3 2:AAAAAA,BBB,C:1,2,3:1e-1,2e-2,3e-3:AAA,B:1,2:1e-1,2e-2:A,BB,CCC:1,2,3:1e-1,2e-2,3e-3 +1 3162008 . TAGGG CAGGG,CAGGT 238 PASS IA8=10,.;IA16=1000,.;IA32=100000,.;IAF=3e-3,.;CIGAR=1X4M,1X3M1X GT:F8:F16:F32:FF 0/1:10:1000:100000:3e-3 2:.:.:.:. +1 3162009 . TAGGG CAGGG,CAGGT 238 PASS IA8=.;IA16=.;IA32=.;IAF=.;CIGAR=1X4M,1X3M1X GT:F8:F16:F32:FF 0/1:10:1000:100000:3e-3 2:.:.:.:. +1 3162010 . TAGGG CAGGG,CAGGT 238 PASS I8=.;I16=.;I32=.;IF=.;CIGAR=1X4M,1X3M1X GT:F8:F16:F32:FF 0/1:10:1000:100000:3e-3 2:.:.:.:. diff --git a/tsv2vcf.c b/tsv2vcf.c new file mode 100644 index 0000000..2e1aa52 --- /dev/null +++ b/tsv2vcf.c @@ -0,0 +1,122 @@ +/* tsv2vcf.c -- convert from whitespace-separated fields to VCF + + Copyright (C) 2014 Genome Research Ltd. + + Author: Petr Danecek + + Permission is hereby granted, free of charge, to any person obtaining a copy + of this software and associated documentation files (the "Software"), to deal + in the Software without restriction, including without limitation the rights + to use, copy, modify, merge, publish, distribute, sublicense, and/or sell + copies of the Software, and to permit persons to whom the Software is + furnished to do so, subject to the following conditions: + + The above copyright notice and this permission notice shall be included in + all copies or substantial portions of the Software. + + THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR + IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, + FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE + AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER + LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, + OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN + THE SOFTWARE. +*/ + +#include +#include +#include "tsv2vcf.h" + +tsv_t *tsv_init(const char *str) +{ + tsv_t *tsv = (tsv_t *) calloc(1,sizeof(tsv_t)); + kstring_t tmp = {0,0,0}; + const char *ss = str, *se = ss; + tsv->ncols = 0; + while ( *ss ) + { + if ( *se && *se!=',' ) { se++; continue; } + tsv->ncols++; + tsv->cols = (tsv_col_t*) realloc(tsv->cols,sizeof(tsv_col_t)*tsv->ncols); + tsv->cols[tsv->ncols-1].name = NULL; + tsv->cols[tsv->ncols-1].setter = NULL; + tmp.l = 0; + kputsn(ss, se-ss, &tmp); + if ( strcasecmp("-",tmp.s) ) + tsv->cols[tsv->ncols-1].name = strdup(tmp.s); + if ( !*se ) break; + ss = ++se; + } + free(tmp.s); + return tsv; +} + +void tsv_destroy(tsv_t *tsv) +{ + int i; + for (i=0; incols; i++) free(tsv->cols[i].name); + free(tsv->cols); + free(tsv); +} + +int tsv_register(tsv_t *tsv, const char *id, tsv_setter_t setter, void *usr) +{ + int i; + for (i=0; incols; i++) + { + if ( !tsv->cols[i].name || strcasecmp(tsv->cols[i].name,id) ) continue; + tsv->cols[i].setter = setter; + tsv->cols[i].usr = usr; + return 0; + } + return -1; +} + +int tsv_parse(tsv_t *tsv, bcf1_t *rec, char *str) +{ + int status = 0; + tsv->icol = 0; + tsv->ss = tsv->se = str; + while ( *tsv->ss && tsv->icol < tsv->ncols ) + { + while ( *tsv->se && !isspace(*tsv->se) ) tsv->se++; + if ( tsv->cols[tsv->icol].setter ) + { + int ret = tsv->cols[tsv->icol].setter(tsv,rec,tsv->cols[tsv->icol].usr); + if ( ret<0 ) return -1; + status++; + } + while ( *tsv->se && isspace(*tsv->se) ) tsv->se++; + tsv->ss = tsv->se; + tsv->icol++; + } + return status ? 0 : -1; +} + +int tsv_setter_chrom(tsv_t *tsv, bcf1_t *rec, void *usr) +{ + char tmp = *tsv->se; + *tsv->se = 0; + rec->rid = bcf_hdr_name2id((bcf_hdr_t*)usr, tsv->ss); + *tsv->se = tmp; + return rec->rid==-1 ? -1 : 0; +} + +int tsv_setter_pos(tsv_t *tsv, bcf1_t *rec, void *usr) +{ + char *endptr; + rec->pos = strtol(tsv->ss, &endptr, 10) - 1; + if ( tsv->ss==endptr ) return -1; + return 0; +} + +int tsv_setter_id(tsv_t *tsv, bcf1_t *rec, void *usr) +{ + char tmp = *tsv->se; + *tsv->se = 0; + bcf_update_id((bcf_hdr_t*)usr, rec, tsv->ss); + *tsv->se = tmp; + return 0; +} + + diff --git a/tsv2vcf.h b/tsv2vcf.h new file mode 100644 index 0000000..6fe5b45 --- /dev/null +++ b/tsv2vcf.h @@ -0,0 +1,85 @@ +/* tsv2vcf.h -- convert from whitespace-separated fields to VCF + + Copyright (C) 2014 Genome Research Ltd. + + Author: Petr Danecek + + Permission is hereby granted, free of charge, to any person obtaining a copy + of this software and associated documentation files (the "Software"), to deal + in the Software without restriction, including without limitation the rights + to use, copy, modify, merge, publish, distribute, sublicense, and/or sell + copies of the Software, and to permit persons to whom the Software is + furnished to do so, subject to the following conditions: + + The above copyright notice and this permission notice shall be included in + all copies or substantial portions of the Software. + + THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR + IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, + FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE + AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER + LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, + OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN + THE SOFTWARE. +*/ + +#ifndef __TSV2VCF_H__ +#define __TSV2VCF_H__ + +#include + +typedef struct _tsv_t tsv_t; +typedef int (*tsv_setter_t)(tsv_t *, bcf1_t *, void *); + +typedef struct +{ + char *name; + tsv_setter_t setter; + void *usr; +} +tsv_col_t; + +struct _tsv_t +{ + int ncols, icol; + tsv_col_t *cols; + char *se, *ss; +}; + +tsv_t *tsv_init(const char *str); +void tsv_destroy(tsv_t *tsv); +int tsv_register(tsv_t *tsv, const char *id, tsv_setter_t setter, void *usr); + +/** + * tsv_parse() - parse tsv line and fill VCF record + * Returns 0 on success or -1 on parse error + */ +int tsv_parse(tsv_t *tsv, bcf1_t *rec, char *str); + +/** + * tstv_next() - position ss,se to next field; first pass with ss=se=str + * Returns 0 on success, or -1 if no more fields + */ +static inline int tsv_next(tsv_t *tsv) +{ + if ( !*tsv->se ) return -1; + if ( tsv->ss==tsv->se ) + { + while ( *tsv->se && !isspace(*tsv->se) ) tsv->se++; + return 0; + } + while ( *tsv->se && isspace(*tsv->se) ) tsv->se++; + tsv->ss = tsv->se; + while ( *tsv->se && !isspace(*tsv->se) ) tsv->se++; + return 0; +} + +/** + * The setters return 0 on success or negative value if the line is to be skipped. + */ +int tsv_setter_chrom(tsv_t *tsv, bcf1_t *rec, void *usr); +int tsv_setter_pos(tsv_t *tsv, bcf1_t *rec, void *usr); +int tsv_setter_id(tsv_t *tsv, bcf1_t *rec, void *usr); + +#endif + diff --git a/vcfannotate.c b/vcfannotate.c new file mode 100644 index 0000000..e6efda9 --- /dev/null +++ b/vcfannotate.c @@ -0,0 +1,2020 @@ +/* vcfannotate.c -- Annotate and edit VCF/BCF files. + + Copyright (C) 2013-2016 Genome Research Ltd. + + Author: Petr Danecek + +Permission is hereby granted, free of charge, to any person obtaining a copy +of this software and associated documentation files (the "Software"), to deal +in the Software without restriction, including without limitation the rights +to use, copy, modify, merge, publish, distribute, sublicense, and/or sell +copies of the Software, and to permit persons to whom the Software is +furnished to do so, subject to the following conditions: + +The above copyright notice and this permission notice shall be included in +all copies or substantial portions of the Software. + +THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE +AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER +LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, +OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN +THE SOFTWARE. */ + +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include "bcftools.h" +#include "vcmp.h" +#include "filter.h" +#include "convert.h" +#include "smpl_ilist.h" + +struct _args_t; + +typedef struct _rm_tag_t +{ + char *key; + int hdr_id; + void (*handler)(struct _args_t *, bcf1_t *, struct _rm_tag_t *); +} +rm_tag_t; + +typedef struct +{ + char **cols; + int ncols, mcols; + char **als; + int nals, mals; + kstring_t line; + int rid, start, end; +} +annot_line_t; + +#define REPLACE_MISSING 0 // replace only missing values +#define REPLACE_ALL 1 // replace both missing and existing values +#define REPLACE_NON_MISSING 2 // replace only if tgt is not missing +#define SET_OR_APPEND 3 // set new value if missing or non-existent, append otherwise +typedef struct _annot_col_t +{ + int icol, replace, number; // number: one of BCF_VL_* types + char *hdr_key_src, *hdr_key_dst; + int (*setter)(struct _args_t *, bcf1_t *, struct _annot_col_t *, void*); +} +annot_col_t; + +// Logic of the filters: include or exclude sites which match the filters? +#define FLT_INCLUDE 1 +#define FLT_EXCLUDE 2 + +#define MARK_LISTED 1 +#define MARK_UNLISTED 2 + +typedef struct _args_t +{ + bcf_srs_t *files; + bcf_hdr_t *hdr, *hdr_out; + htsFile *out_fh; + int output_type, n_threads; + bcf_sr_regions_t *tgts; + + filter_t *filter; + char *filter_str; + int filter_logic; // include or exclude sites which match the filters? One of FLT_INCLUDE/FLT_EXCLUDE + + rm_tag_t *rm; // tags scheduled for removal + int nrm; + int flt_keep_pass; // when all filters removed, reset to PASS + + vcmp_t *vcmp; // for matching annotation and VCF lines by allele + annot_line_t *alines; // buffered annotation lines + int nalines, malines; + int ref_idx, alt_idx, chr_idx, from_idx, to_idx; // -1 if not present + annot_col_t *cols; // column indexes and setters + int ncols; + + char *set_ids_fmt; + convert_t *set_ids; + int set_ids_replace; + + int nsmpl_annot; + int *sample_map, nsample_map, sample_is_file; // map[idst] -> isrc + int mtmpi, mtmpf, mtmps; + int mtmpi2, mtmpf2, mtmps2; + int mtmpi3, mtmpf3, mtmps3; + int32_t *tmpi, *tmpi2, *tmpi3; + float *tmpf, *tmpf2, *tmpf3; + char *tmps, *tmps2, **tmpp, **tmpp2; + kstring_t tmpks; + + char **argv, *output_fname, *targets_fname, *regions_list, *header_fname; + char *remove_annots, *columns, *rename_chrs, *sample_names, *mark_sites; + int argc, drop_header, record_cmd_line, tgts_is_vcf, mark_sites_logic; +} +args_t; + +char *msprintf(const char *fmt, ...); + +void remove_id(args_t *args, bcf1_t *line, rm_tag_t *tag) +{ + bcf_update_id(args->hdr,line,NULL); +} +void remove_filter(args_t *args, bcf1_t *line, rm_tag_t *tag) +{ + if ( !tag->key ) bcf_update_filter(args->hdr, line, NULL, args->flt_keep_pass); + else bcf_remove_filter(args->hdr, line, tag->hdr_id, args->flt_keep_pass); +} +void remove_qual(args_t *args, bcf1_t *line, rm_tag_t *tag) +{ + bcf_float_set_missing(line->qual); +} +void remove_info(args_t *args, bcf1_t *line, rm_tag_t *tag) +{ + // remove all INFO fields + if ( !(line->unpacked & BCF_UN_INFO) ) bcf_unpack(line, BCF_UN_INFO); + + int i; + for (i=0; in_info; i++) + { + bcf_info_t *inf = &line->d.info[i]; + if ( inf->vptr_free ) + { + free(inf->vptr - inf->vptr_off); + inf->vptr_free = 0; + } + line->d.shared_dirty |= BCF1_DIRTY_INF; + inf->vptr = NULL; + inf->vptr_off = inf->vptr_len = 0; + } +} +void remove_info_tag(args_t *args, bcf1_t *line, rm_tag_t *tag) +{ + bcf_update_info(args->hdr, line, tag->key, NULL, 0, BCF_HT_INT); // the type does not matter with n=0 +} +void remove_format_tag(args_t *args, bcf1_t *line, rm_tag_t *tag) +{ + bcf_update_format(args->hdr, line, tag->key, NULL, 0, BCF_HT_INT); // the type does not matter with n=0 +} +void remove_format(args_t *args, bcf1_t *line, rm_tag_t *tag) +{ + // remove all FORMAT fields except GT + if ( !(line->unpacked & BCF_UN_FMT) ) bcf_unpack(line, BCF_UN_FMT); + + int i; + for (i=0; in_fmt; i++) + { + bcf_fmt_t *fmt = &line->d.fmt[i]; + const char *key = bcf_hdr_int2id(args->hdr,BCF_DT_ID,fmt->id); + if ( key[0]=='G' && key[1]=='T' && !key[2] ) continue; + + if ( fmt->p_free ) + { + free(fmt->p - fmt->p_off); + fmt->p_free = 0; + } + line->d.indiv_dirty = 1; + fmt->p = NULL; + } +} + +#include "htslib/khash.h" +KHASH_MAP_INIT_STR(vdict, bcf_idinfo_t) +typedef khash_t(vdict) vdict_t; + +static void remove_hdr_lines(bcf_hdr_t *hdr, int type) +{ + int i = 0, nrm = 0; + while ( inhrec ) + { + if ( hdr->hrec[i]->type!=type ) { i++; continue; } + bcf_hrec_t *hrec = hdr->hrec[i]; + if ( type==BCF_HL_FMT || type==BCF_HL_INFO || type==BCF_HL_FMT || type== BCF_HL_CTG ) + { + // everything except FORMAT/GT + int id = bcf_hrec_find_key(hrec, "ID"); + if ( id>=0 ) + { + if ( type==BCF_HL_FMT && !strcmp(hrec->vals[id],"GT") ) { i++; continue; } + vdict_t *d = type==BCF_HL_CTG ? (vdict_t*)hdr->dict[BCF_DT_CTG] : (vdict_t*)hdr->dict[BCF_DT_ID]; + khint_t k = kh_get(vdict, d, hdr->hrec[i]->vals[id]); + kh_val(d, k).hrec[type==BCF_HL_CTG?0:type] = NULL; + kh_val(d, k).info[type] |= 0xf; + } + } + nrm++; + hdr->nhrec--; + if ( i < hdr->nhrec ) + memmove(&hdr->hrec[i],&hdr->hrec[i+1],(hdr->nhrec-i)*sizeof(bcf_hrec_t*)); + bcf_hrec_destroy(hrec); + } + if ( nrm ) bcf_hdr_sync(hdr); +} + +static void init_remove_annots(args_t *args) +{ + int keep_info = 0, keep_fmt = 0, keep_flt = 0; + void *keep = khash_str2int_init(); + kstring_t str = {0,0,0}; + char *ss = args->remove_annots; + while ( *ss ) + { + args->nrm++; + args->rm = (rm_tag_t*) realloc(args->rm,sizeof(rm_tag_t)*args->nrm); + rm_tag_t *tag = &args->rm[args->nrm-1]; + tag->key = NULL; + + int type = BCF_HL_GEN; + if ( !strncasecmp("INFO/",ss,5) ) { type = BCF_HL_INFO; ss += 5; } + else if ( !strncasecmp("INF/",ss,4) ) { type = BCF_HL_INFO; ss += 4; } + else if ( !strncasecmp("FORMAT/",ss,7) ) { type = BCF_HL_FMT; ss += 7; } + else if ( !strncasecmp("FMT/",ss,4) ) { type = BCF_HL_FMT; ss += 4; } + else if ( !strncasecmp("FILTER/",ss,7) ) { type = BCF_HL_FLT; ss += 7; } + else if ( !strncasecmp("^INFO/",ss,6) ) { type = BCF_HL_INFO; ss += 6; keep_info = 1; } + else if ( !strncasecmp("^INF/",ss,5) ) { type = BCF_HL_INFO; ss += 5; keep_info = 1; } + else if ( !strncasecmp("^FORMAT/",ss,8) ) { type = BCF_HL_FMT; ss += 8; keep_fmt = 1; } + else if ( !strncasecmp("^FMT/",ss,5) ) { type = BCF_HL_FMT; ss += 5; keep_fmt = 1; } + else if ( !strncasecmp("^FILTER/",ss,8) ) { type = BCF_HL_FLT; ss += 8; keep_flt = 1; } + + char *se = ss; + while ( *se && *se!=',' ) se++; + str.l = 0; + kputsn(ss, se-ss, &str); + + if ( type==BCF_HL_FLT ) + { + if ( !keep_flt ) + { + args->flt_keep_pass = 1; + tag->handler = remove_filter; + tag->key = strdup(str.s); + tag->hdr_id = bcf_hdr_id2int(args->hdr, BCF_DT_ID, tag->key); + if ( !bcf_hdr_idinfo_exists(args->hdr,BCF_HL_FLT,tag->hdr_id) ) error("Cannot remove %s, not defined in the header.\n", str.s); + bcf_hdr_remove(args->hdr_out,BCF_HL_FLT,tag->key); + } + else + { + int value, ret = khash_str2int_get(keep, str.s, &value); + if ( ret==-1 ) khash_str2int_set(keep, strdup(str.s),1<nrm--; + } + } + else if ( type!=BCF_HL_GEN ) + { + int id = bcf_hdr_id2int(args->hdr,BCF_DT_ID,str.s); + if ( !bcf_hdr_idinfo_exists(args->hdr,type,id) ) + { + fprintf(stderr,"Warning: The tag \"%s\" not defined in the header\n", str.s); + args->nrm--; + } + else if ( (type==BCF_HL_FMT && keep_fmt) || (type==BCF_HL_INFO && keep_info) ) + { + int value, ret = khash_str2int_get(keep, str.s, &value); + if ( ret==-1 ) khash_str2int_set(keep, strdup(str.s),1<nrm--; + } + else + { + tag->key = strdup(str.s); + if ( type==BCF_HL_INFO ) tag->handler = remove_info_tag; + else if ( type==BCF_HL_FMT ) tag->handler = remove_format_tag; + bcf_hdr_remove(args->hdr_out,type,tag->key); + } + } + else if ( !strcasecmp("ID",str.s) ) tag->handler = remove_id; + else if ( !strcasecmp("FILTER",str.s) ) + { + tag->handler = remove_filter; + remove_hdr_lines(args->hdr_out,BCF_HL_FLT); + } + else if ( !strcasecmp("QUAL",str.s) ) tag->handler = remove_qual; + else if ( !strcasecmp("INFO",str.s) ) + { + tag->handler = remove_info; + remove_hdr_lines(args->hdr_out,BCF_HL_INFO); + } + else if ( !strcasecmp("FMT",str.s) || !strcasecmp("FORMAT",str.s) ) + { + tag->handler = remove_format; + remove_hdr_lines(args->hdr_out,BCF_HL_FMT); + } + else if ( str.l ) + { + if ( str.s[0]=='#' && str.s[1]=='#' ) + bcf_hdr_remove(args->hdr_out,BCF_HL_GEN,str.s+2); + else + bcf_hdr_remove(args->hdr_out,BCF_HL_STR,str.s); + args->nrm--; + } + + ss = *se ? se+1 : se; + } + free(str.s); + if ( keep_flt || keep_info || keep_fmt ) + { + int j; + for (j=0; jhdr->nhrec; j++) + { + bcf_hrec_t *hrec = args->hdr->hrec[j]; + if ( hrec->type!=BCF_HL_FLT && hrec->type!=BCF_HL_INFO && hrec->type!=BCF_HL_FMT ) continue; + if ( !keep_flt && hrec->type==BCF_HL_FLT ) continue; + if ( !keep_info && hrec->type==BCF_HL_INFO ) continue; + if ( !keep_fmt && hrec->type==BCF_HL_FMT ) continue; + int k = bcf_hrec_find_key(hrec,"ID"); + assert( k>=0 ); // this should always be true for valid VCFs + int value, ret = khash_str2int_get(keep,hrec->vals[k],&value); + if ( ret==0 && value>>hrec->type ) // keep + { + if ( hrec->type==BCF_HL_FLT && !strcmp("PASS",hrec->vals[k]) ) args->flt_keep_pass = 1; + continue; + } + args->nrm++; + args->rm = (rm_tag_t*) realloc(args->rm,sizeof(rm_tag_t)*args->nrm); + rm_tag_t *tag = &args->rm[args->nrm-1]; + if ( hrec->type==BCF_HL_INFO ) tag->handler = remove_info_tag; + else if ( hrec->type==BCF_HL_FMT ) tag->handler = remove_format_tag; + else + { + tag->handler = remove_filter; + tag->hdr_id = bcf_hdr_id2int(args->hdr, BCF_DT_ID, hrec->vals[k]); + } + tag->key = strdup(hrec->vals[k]); + bcf_hdr_remove(args->hdr_out,hrec->type,tag->key); + } + } + khash_str2int_destroy_free(keep); + if ( !args->nrm ) error("No matching tag in -x %s\n", args->remove_annots); + bcf_hdr_sync(args->hdr_out); +} +static void init_header_lines(args_t *args) +{ + htsFile *file = hts_open(args->header_fname, "rb"); + if ( !file ) error("Error reading %s\n", args->header_fname); + kstring_t str = {0,0,0}; + while ( hts_getline(file, KS_SEP_LINE, &str) > 0 ) + { + if ( bcf_hdr_append(args->hdr_out,str.s) ) error("Could not parse %s: %s\n", args->header_fname, str.s); + bcf_hdr_append(args->hdr,str.s); // the input file may not have the header line if run with -h (and nothing else) + } + hts_close(file); + free(str.s); + bcf_hdr_sync(args->hdr_out); + bcf_hdr_sync(args->hdr); +} +static int setter_filter(args_t *args, bcf1_t *line, annot_col_t *col, void *data) +{ + // note: so far this works only with one filter, not a list of filters + annot_line_t *tab = (annot_line_t*) data; + if ( tab->cols[col->icol] && tab->cols[col->icol][0]=='.' && !tab->cols[col->icol][1] ) return 0; // don't replace with "." + hts_expand(int,1,args->mtmpi,args->tmpi); + args->tmpi[0] = bcf_hdr_id2int(args->hdr_out, BCF_DT_ID, tab->cols[col->icol]); + if ( args->tmpi[0]<0 ) error("The FILTER is not defined in the header: %s\n", tab->cols[col->icol]); + if ( col->replace==SET_OR_APPEND ) { bcf_add_filter(args->hdr_out,line,args->tmpi[0]); return 0; } + if ( col->replace!=REPLACE_MISSING ) + { + bcf_update_filter(args->hdr_out,line,NULL,0); + bcf_update_filter(args->hdr_out,line,args->tmpi,1); + return 0; + } + + // only update missing FILTER + if ( !(line->unpacked & BCF_UN_FLT) ) bcf_unpack(line, BCF_UN_FLT); + if ( !line->d.n_flt ) + bcf_update_filter(args->hdr_out,line,args->tmpi,1); + return 0; +} +static int vcf_setter_filter(args_t *args, bcf1_t *line, annot_col_t *col, void *data) +{ + int i; + bcf1_t *rec = (bcf1_t*) data; + if ( !(rec->unpacked & BCF_UN_FLT) ) bcf_unpack(rec, BCF_UN_FLT); + if ( !(line->unpacked & BCF_UN_FLT) ) bcf_unpack(line, BCF_UN_FLT); + if ( !rec->d.n_flt ) return 0; // don't overwrite with a missing value + if ( col->replace==SET_OR_APPEND || col->replace==REPLACE_MISSING ) + { + if ( col->replace==REPLACE_MISSING && line->d.n_flt ) return 0; // only update missing FILTER + for (i=0; id.n_flt; i++) + { + const char *flt = bcf_hdr_int2id(args->files->readers[1].header, BCF_DT_ID, rec->d.flt[i]); + bcf_add_filter(args->hdr_out,line,bcf_hdr_id2int(args->hdr_out, BCF_DT_ID, flt)); + } + return 0; + } + hts_expand(int,rec->d.n_flt,args->mtmpi,args->tmpi); + for (i=0; id.n_flt; i++) + { + const char *flt = bcf_hdr_int2id(args->files->readers[1].header, BCF_DT_ID, rec->d.flt[i]); + args->tmpi[i] = bcf_hdr_id2int(args->hdr_out, BCF_DT_ID, flt); + } + bcf_update_filter(args->hdr_out,line,NULL,0); + bcf_update_filter(args->hdr_out,line,args->tmpi,rec->d.n_flt); + return 0; +} +static int setter_id(args_t *args, bcf1_t *line, annot_col_t *col, void *data) +{ + // possible cases: + // IN ANNOT OUT ACHIEVED_BY + // x y x -c +ID + // x y y -c ID + // x y x,y -c =ID + // x . x -c +ID, ID + // x . . -x ID + // . y y -c +ID, -c ID + // + annot_line_t *tab = (annot_line_t*) data; + if ( tab->cols[col->icol] && tab->cols[col->icol][0]=='.' && !tab->cols[col->icol][1] ) return 0; // don't replace with "." + if ( col->replace==SET_OR_APPEND ) return bcf_add_id(args->hdr_out,line,tab->cols[col->icol]); + if ( col->replace!=REPLACE_MISSING ) return bcf_update_id(args->hdr_out,line,tab->cols[col->icol]); + + // running with +ID, only update missing ids + if ( !line->d.id || (line->d.id[0]=='.' && !line->d.id[1]) ) + return bcf_update_id(args->hdr_out,line,tab->cols[col->icol]); + return 0; +} +static int vcf_setter_id(args_t *args, bcf1_t *line, annot_col_t *col, void *data) +{ + bcf1_t *rec = (bcf1_t*) data; + if ( rec->d.id && rec->d.id[0]=='.' && !rec->d.id[1] ) return 0; // don't replace with "." + if ( col->replace==SET_OR_APPEND ) return bcf_add_id(args->hdr_out,line,rec->d.id); + if ( col->replace!=REPLACE_MISSING ) return bcf_update_id(args->hdr_out,line,rec->d.id); + + // running with +ID, only update missing ids + if ( !line->d.id || (line->d.id[0]=='.' && !line->d.id[1]) ) + return bcf_update_id(args->hdr_out,line,rec->d.id); + return 0; +} +static int setter_qual(args_t *args, bcf1_t *line, annot_col_t *col, void *data) +{ + annot_line_t *tab = (annot_line_t*) data; + char *str = tab->cols[col->icol]; + if ( str[0]=='.' && str[1]==0 ) return 0; // empty + + if ( col->replace==REPLACE_MISSING && !bcf_float_is_missing(line->qual) ) return 0; + + line->qual = strtod(str, &str); + if ( str == tab->cols[col->icol] ) + error("Could not parse %s at %s:%d .. [%s]\n", col->hdr_key_src,bcf_seqname(args->hdr,line),line->pos+1,tab->cols[col->icol]); + return 0; +} +static int vcf_setter_qual(args_t *args, bcf1_t *line, annot_col_t *col, void *data) +{ + bcf1_t *rec = (bcf1_t*) data; + if ( bcf_float_is_missing(rec->qual) ) return 0; + if ( col->replace==REPLACE_MISSING && !bcf_float_is_missing(line->qual) ) return 0; + line->qual = rec->qual; + return 0; +} +static int setter_info_flag(args_t *args, bcf1_t *line, annot_col_t *col, void *data) +{ + annot_line_t *tab = (annot_line_t*) data; + char *str = tab->cols[col->icol]; + if ( str[0]=='.' && str[1]==0 ) return 0; + + if ( str[0]=='1' && str[1]==0 ) return bcf_update_info_flag(args->hdr_out,line,col->hdr_key_dst,NULL,1); + if ( str[0]=='0' && str[1]==0 ) return bcf_update_info_flag(args->hdr_out,line,col->hdr_key_dst,NULL,0); + error("Could not parse %s at %s:%d .. [%s]\n", bcf_seqname(args->hdr,line),line->pos+1,tab->cols[col->icol]); + return -1; +} +static int vcf_setter_info_flag(args_t *args, bcf1_t *line, annot_col_t *col, void *data) +{ + bcf1_t *rec = (bcf1_t*) data; + int flag = bcf_get_info_flag(args->files->readers[1].header,rec,col->hdr_key_src,NULL,NULL); + bcf_update_info_flag(args->hdr_out,line,col->hdr_key_dst,NULL,flag); + return 0; +} +static int setter_ARinfo_int32(args_t *args, bcf1_t *line, annot_col_t *col, int nals, char **als, int ntmpi) +{ + if ( col->number==BCF_VL_A && ntmpi!=nals-1 && (ntmpi!=1 || args->tmpi[0]!=bcf_int32_missing || args->tmpi[1]!=bcf_int32_vector_end) ) + error("Incorrect number of values (%d) for the %s tag at %s:%d\n", ntmpi,col->hdr_key_src,bcf_seqname(args->hdr,line),line->pos+1); + else if ( col->number==BCF_VL_R && ntmpi!=nals && (ntmpi!=1 || args->tmpi[0]!=bcf_int32_missing || args->tmpi[1]!=bcf_int32_vector_end) ) + error("Incorrect number of values (%d) for the %s tag at %s:%d\n", ntmpi,col->hdr_key_src,bcf_seqname(args->hdr,line),line->pos+1); + + int ndst = col->number==BCF_VL_A ? line->n_allele - 1 : line->n_allele; + int *map = vcmp_map_ARvalues(args->vcmp,ndst,nals,als,line->n_allele,line->d.allele); + if ( !map ) error("REF alleles not compatible at %s:%d\n"); + + // fill in any missing values in the target VCF (or all, if not present) + int ntmpi2 = bcf_get_info_float(args->hdr, line, col->hdr_key_dst, &args->tmpi2, &args->mtmpi2); + if ( ntmpi2 < ndst ) hts_expand(int32_t,ndst,args->mtmpi2,args->tmpi2); + + int i; + for (i=0; itmpi2[i] = bcf_int32_missing; + continue; + } + if ( ntmpi2==ndst && col->replace==REPLACE_MISSING + && args->tmpi2[i]!=bcf_int32_missing + && args->tmpi2[i]!=bcf_int32_vector_end ) continue; + + args->tmpi2[i] = args->tmpi[ map[i] ]; + } + bcf_update_info_int32(args->hdr_out,line,col->hdr_key_dst,args->tmpi2,ndst); + return 0; +} +static int setter_info_int(args_t *args, bcf1_t *line, annot_col_t *col, void *data) +{ + annot_line_t *tab = (annot_line_t*) data; + char *str = tab->cols[col->icol], *end = str; + if ( str[0]=='.' && str[1]==0 ) return 0; + + int ntmpi = 0; + while ( *end ) + { + int val = strtol(str, &end, 10); + if ( end==str ) + error("Could not parse %s at %s:%d .. [%s]\n", bcf_seqname(args->hdr,line),line->pos+1,tab->cols[col->icol]); + ntmpi++; + hts_expand(int32_t,ntmpi,args->mtmpi,args->tmpi); + args->tmpi[ntmpi-1] = val; + str = end+1; + } + + if ( col->number==BCF_VL_A || col->number==BCF_VL_R ) + return setter_ARinfo_int32(args,line,col,tab->nals,tab->als,ntmpi); + + if ( col->replace==REPLACE_MISSING ) + { + int ret = bcf_get_info_int32(args->hdr, line, col->hdr_key_dst, &args->tmpi2, &args->mtmpi2); + if ( ret>0 && args->tmpi2[0]!=bcf_int32_missing ) return 0; + } + + bcf_update_info_int32(args->hdr_out,line,col->hdr_key_dst,args->tmpi,ntmpi); + return 0; +} +static int vcf_setter_info_int(args_t *args, bcf1_t *line, annot_col_t *col, void *data) +{ + bcf1_t *rec = (bcf1_t*) data; + int ntmpi = bcf_get_info_int32(args->files->readers[1].header,rec,col->hdr_key_src,&args->tmpi,&args->mtmpi); + if ( ntmpi < 0 ) return 0; // nothing to add + + if ( col->number==BCF_VL_A || col->number==BCF_VL_R ) + return setter_ARinfo_int32(args,line,col,rec->n_allele,rec->d.allele,ntmpi); + + if ( col->replace==REPLACE_MISSING ) + { + int ret = bcf_get_info_int32(args->hdr, line, col->hdr_key_dst, &args->tmpi2, &args->mtmpi2); + if ( ret>0 && args->tmpi2[0]!=bcf_int32_missing ) return 0; + } + + bcf_update_info_int32(args->hdr_out,line,col->hdr_key_dst,args->tmpi,ntmpi); + return 0; +} +static int setter_ARinfo_real(args_t *args, bcf1_t *line, annot_col_t *col, int nals, char **als, int ntmpf) +{ + if ( col->number==BCF_VL_A && ntmpf!=nals-1 && (ntmpf!=1 || !bcf_float_is_missing(args->tmpf[0]) || !bcf_float_is_vector_end(args->tmpf[0])) ) + error("Incorrect number of values (%d) for the %s tag at %s:%d\n", ntmpf,col->hdr_key_src,bcf_seqname(args->hdr,line),line->pos+1); + else if ( col->number==BCF_VL_R && ntmpf!=nals && (ntmpf!=1 || !bcf_float_is_missing(args->tmpf[0]) || !bcf_float_is_vector_end(args->tmpf[0])) ) + error("Incorrect number of values (%d) for the %s tag at %s:%d\n", ntmpf,col->hdr_key_src,bcf_seqname(args->hdr,line),line->pos+1); + + int ndst = col->number==BCF_VL_A ? line->n_allele - 1 : line->n_allele; + int *map = vcmp_map_ARvalues(args->vcmp,ndst,nals,als,line->n_allele,line->d.allele); + if ( !map ) error("REF alleles not compatible at %s:%d\n"); + + // fill in any missing values in the target VCF (or all, if not present) + int ntmpf2 = bcf_get_info_float(args->hdr, line, col->hdr_key_dst, &args->tmpf2, &args->mtmpf2); + if ( ntmpf2 < ndst ) hts_expand(float,ndst,args->mtmpf2,args->tmpf2); + + int i; + for (i=0; itmpf2[i]); + continue; + } + if ( ntmpf2==ndst && col->replace==REPLACE_MISSING + && !bcf_float_is_missing(args->tmpf2[i]) + && !bcf_float_is_vector_end(args->tmpf2[i]) ) continue; + + args->tmpf2[i] = args->tmpf[ map[i] ]; + } + bcf_update_info_float(args->hdr_out,line,col->hdr_key_dst,args->tmpf2,ndst); + return 0; +} +static int setter_info_real(args_t *args, bcf1_t *line, annot_col_t *col, void *data) +{ + annot_line_t *tab = (annot_line_t*) data; + char *str = tab->cols[col->icol], *end = str; + if ( str[0]=='.' && str[1]==0 ) return 0; + + int ntmpf = 0; + while ( *end ) + { + double val = strtod(str, &end); + if ( end==str ) + error("Could not parse %s at %s:%d .. [%s]\n", bcf_seqname(args->hdr,line),line->pos+1,tab->cols[col->icol]); + ntmpf++; + hts_expand(float,ntmpf,args->mtmpf,args->tmpf); + args->tmpf[ntmpf-1] = val; + str = end+1; + } + + if ( col->number==BCF_VL_A || col->number==BCF_VL_R ) + return setter_ARinfo_real(args,line,col,tab->nals,tab->als,ntmpf); + + if ( col->replace==REPLACE_MISSING ) + { + int ret = bcf_get_info_float(args->hdr, line, col->hdr_key_dst, &args->tmpf2, &args->mtmpf2); + if ( ret>0 && !bcf_float_is_missing(args->tmpf2[0]) ) return 0; + } + + bcf_update_info_float(args->hdr_out,line,col->hdr_key_dst,args->tmpf,ntmpf); + return 0; +} +static int vcf_setter_info_real(args_t *args, bcf1_t *line, annot_col_t *col, void *data) +{ + bcf1_t *rec = (bcf1_t*) data; + int ntmpf = bcf_get_info_float(args->files->readers[1].header,rec,col->hdr_key_src,&args->tmpf,&args->mtmpf); + if ( ntmpf < 0 ) return 0; // nothing to add + + if ( col->number==BCF_VL_A || col->number==BCF_VL_R ) + return setter_ARinfo_real(args,line,col,rec->n_allele,rec->d.allele,ntmpf); + + if ( col->replace==REPLACE_MISSING ) + { + int ret = bcf_get_info_float(args->hdr, line, col->hdr_key_dst, &args->tmpf2, &args->mtmpf2); + if ( ret>0 && !bcf_float_is_missing(args->tmpf2[0]) ) return 0; + } + + bcf_update_info_float(args->hdr_out,line,col->hdr_key_dst,args->tmpf,ntmpf); + return 0; +} +int copy_string_field(char *src, int isrc, int src_len, kstring_t *dst, int idst); // see vcfmerge.c +static int setter_ARinfo_string(args_t *args, bcf1_t *line, annot_col_t *col, int nals, char **als) +{ + int nsrc = 1, lsrc = 0; + while ( args->tmps[lsrc] ) + { + if ( args->tmps[lsrc]==',' ) nsrc++; + lsrc++; + } + if ( col->number==BCF_VL_A && nsrc!=nals-1 && (nsrc!=1 || args->tmps[0]!='.' || args->tmps[1]!=0 ) ) + error("Incorrect number of values (%d) for the %s tag at %s:%d\n", nsrc,col->hdr_key_src,bcf_seqname(args->hdr,line),line->pos+1); + else if ( col->number==BCF_VL_R && nsrc!=nals && (nsrc!=1 || args->tmps[0]!='.' || args->tmps[1]!=0 ) ) + error("Incorrect number of values (%d) for the %s tag at %s:%d\n", nsrc,col->hdr_key_src,bcf_seqname(args->hdr,line),line->pos+1); + + int ndst = col->number==BCF_VL_A ? line->n_allele - 1 : line->n_allele; + int *map = vcmp_map_ARvalues(args->vcmp,ndst,nals,als,line->n_allele,line->d.allele); + if ( !map ) error("REF alleles not compatible at %s:%d\n"); + + // fill in any missing values in the target VCF (or all, if not present) + int i, empty = 0, nstr, mstr = args->tmpks.m; + nstr = bcf_get_info_string(args->hdr, line, col->hdr_key_dst, &args->tmpks.s, &mstr); + args->tmpks.m = mstr; + if ( nstr<0 || (nstr==1 && args->tmpks.s[0]=='.' && args->tmpks.s[1]==0) ) + { + empty = 0; + args->tmpks.l = 0; + kputc('.',&args->tmpks); + for (i=1; itmpks); + } + else args->tmpks.l = nstr; + for (i=0; itmpks,i); + continue; + } + if ( col->replace==REPLACE_MISSING ) + { + // Do not replace filled values. The field must be looked up again because + // of realloc in copy_string_field + int n = 0; + char *str = args->tmpks.s; + while ( *str && ntmps,map[i],lsrc,&args->tmpks,i); + assert( ret==0 ); + } + bcf_update_info_string(args->hdr_out,line,col->hdr_key_dst,args->tmpks.s); + return 0; +} +static int setter_info_str(args_t *args, bcf1_t *line, annot_col_t *col, void *data) +{ + annot_line_t *tab = (annot_line_t*) data; + int len = strlen(tab->cols[col->icol]); + if ( !len ) return 0; + hts_expand(char,len+1,args->mtmps,args->tmps); + memcpy(args->tmps,tab->cols[col->icol],len+1); + if ( args->tmps[0]=='.' && args->tmps[1]==0 ) return 0; + + if ( col->number==BCF_VL_A || col->number==BCF_VL_R ) + return setter_ARinfo_string(args,line,col,tab->nals,tab->als); + + if ( col->replace==REPLACE_MISSING ) + { + int ret = bcf_get_info_string(args->hdr, line, col->hdr_key_dst, &args->tmps2, &args->mtmps2); + if ( ret>0 && (args->tmps2[0]!='.' || args->tmps2[1]!=0) ) return 0; + } + + bcf_update_info_string(args->hdr_out,line,col->hdr_key_dst,args->tmps); + return 0; +} +static int vcf_setter_info_str(args_t *args, bcf1_t *line, annot_col_t *col, void *data) +{ + bcf1_t *rec = (bcf1_t*) data; + int ntmps = bcf_get_info_string(args->files->readers[1].header,rec,col->hdr_key_src,&args->tmps,&args->mtmps); + if ( ntmps < 0 ) return 0; // nothing to add + + if ( col->number==BCF_VL_A || col->number==BCF_VL_R ) + return setter_ARinfo_string(args,line,col,rec->n_allele,rec->d.allele); + + if ( col->replace==REPLACE_MISSING ) + { + int ret = bcf_get_info_string(args->hdr, line, col->hdr_key_dst, &args->tmps2, &args->mtmps2); + if ( ret>0 && (args->tmps2[0]!='.' || args->tmps2[1]!=0) ) return 0; + } + + bcf_update_info_string(args->hdr_out,line,col->hdr_key_dst,args->tmps); + return 0; +} +static int vcf_setter_format_gt(args_t *args, bcf1_t *line, annot_col_t *col, void *data) +{ + bcf1_t *rec = (bcf1_t*) data; + int nsrc = bcf_get_genotypes(args->files->readers[1].header,rec,&args->tmpi,&args->mtmpi); + if ( nsrc==-3 ) return 0; // the tag is not present + if ( nsrc<=0 ) return 1; // error + + if ( !args->sample_map ) + return bcf_update_genotypes(args->hdr_out,line,args->tmpi,nsrc); + + int i, j, ndst = bcf_get_genotypes(args->hdr,line,&args->tmpi2,&args->mtmpi2); + if ( ndst > 0 ) ndst /= bcf_hdr_nsamples(args->hdr_out); + nsrc /= bcf_hdr_nsamples(args->files->readers[1].header); + if ( ndst<=0 ) // field not present in dst file + { + if ( col->replace==REPLACE_NON_MISSING ) return 0; + hts_expand(int32_t, nsrc*bcf_hdr_nsamples(args->hdr_out), args->mtmpi2, args->tmpi2); + for (i=0; ihdr_out); i++) + { + int32_t *dst = args->tmpi2 + nsrc*i; + if ( args->sample_map[i]==-1 ) + { + dst[0] = bcf_gt_missing; + for (j=1; jtmpi + nsrc*args->sample_map[i]; + for (j=0; jhdr_out,line,args->tmpi2,nsrc*bcf_hdr_nsamples(args->hdr_out)); + } + else if ( ndst >= nsrc ) + { + for (i=0; ihdr_out); i++) + { + if ( args->sample_map[i]==-1 ) continue; + int32_t *src = args->tmpi + nsrc*args->sample_map[i]; + int32_t *dst = args->tmpi2 + ndst*i; + if ( col->replace==REPLACE_NON_MISSING && bcf_gt_is_missing(dst[0]) ) continue; + if ( col->replace==REPLACE_MISSING && !bcf_gt_is_missing(dst[0]) ) continue; + for (j=0; jhdr_out,line,args->tmpi2,ndst*bcf_hdr_nsamples(args->hdr_out)); + } + else // ndst < nsrc + { + hts_expand(int32_t, nsrc*bcf_hdr_nsamples(args->hdr_out), args->mtmpi3, args->tmpi3); + for (i=0; ihdr_out); i++) + { + int32_t *ori = args->tmpi2 + ndst*i; + int32_t *dst = args->tmpi3 + nsrc*i; + int keep_ori = 0; + if ( args->sample_map[i]==-1 ) keep_ori = 1; + else if ( col->replace==REPLACE_NON_MISSING && bcf_gt_is_missing(ori[0]) ) keep_ori = 1; + else if ( col->replace==REPLACE_MISSING && !bcf_gt_is_missing(ori[0]) ) keep_ori = 1; + if ( keep_ori ) + { + for (j=0; jtmpi + nsrc*args->sample_map[i]; + for (j=0; jhdr_out,line,args->tmpi3,nsrc*bcf_hdr_nsamples(args->hdr_out)); + } +} +static int count_vals(annot_line_t *tab, int icol_beg, int icol_end) +{ + int i, nmax = 1; + for (i=icol_beg; icols[i], *end = str; + if ( str[0]=='.' && !str[1] ) + { + // missing value + if ( !nmax ) nmax = 1; + continue; + } + int n = 1; + while ( *end ) + { + if ( *end==',' ) n++; + end++; + } + if ( nmaxsample_map ) + return bcf_update_format_int32(args->hdr_out,line,col->hdr_key_dst,vals,nvals*args->nsmpl_annot); + + int i, j, ndst = bcf_get_format_int32(args->hdr,line,col->hdr_key_dst,&args->tmpi2,&args->mtmpi2); + if ( ndst > 0 ) ndst /= bcf_hdr_nsamples(args->hdr_out); + if ( ndst<=0 ) + { + if ( col->replace==REPLACE_NON_MISSING ) return 0; // overwrite only if present + hts_expand(int32_t, nvals*bcf_hdr_nsamples(args->hdr_out), args->mtmpi2, args->tmpi2); + for (i=0; ihdr_out); i++) + { + int32_t *dst = args->tmpi2 + nvals*i; + if ( args->sample_map[i]==-1 ) + { + dst[0] = bcf_int32_missing; + for (j=1; jsample_map[i]; + for (j=0; jhdr_out,line,col->hdr_key_dst,args->tmpi2,nvals*bcf_hdr_nsamples(args->hdr_out)); + } + else if ( ndst >= nvals ) + { + for (i=0; ihdr_out); i++) + { + if ( args->sample_map[i]==-1 ) continue; + int32_t *src = vals + nvals*args->sample_map[i]; + int32_t *dst = args->tmpi2 + ndst*i; + // possible cases: + // in annot out + // x y x TAG,-TAG,=TAG .. REPLACE_ALL, REPLACE_NON_MISSING, SET_OR_APPEND + // x y y +TAG .. REPLACE_MISSING + // . y . =TAG .. SET_OR_APPEND + // . y y TAG,+TAG,-TAG .. REPLACE_ALL, REPLACE_MISSING, REPLACE_NON_MISSING + // x . x TAG,+TAG .. REPLACE_ALL, REPLACE_MISSING + // x . . -TAG .. REPLACE_NON_MISSING + if ( col->replace==REPLACE_NON_MISSING ) { if ( dst[0]==bcf_int32_missing ) continue; } + else if ( col->replace==REPLACE_MISSING ) { if ( dst[0]!=bcf_int32_missing ) continue; } + else if ( col->replace==REPLACE_ALL ) { if ( src[0]==bcf_int32_missing ) continue; } + for (j=0; jhdr_out,line,col->hdr_key_dst,args->tmpi2,ndst*bcf_hdr_nsamples(args->hdr_out)); + } + else // ndst < nvals + { + hts_expand(int32_t, nvals*bcf_hdr_nsamples(args->hdr_out), args->mtmpi3, args->tmpi3); + for (i=0; ihdr_out); i++) + { + int32_t *ann = vals + nvals*args->sample_map[i]; + int32_t *ori = args->tmpi2 + ndst*i; // ori vcf line + int32_t *dst = args->tmpi3 + nvals*i; // expanded buffer + int use_new_ann = 1; + if ( args->sample_map[i]==-1 ) use_new_ann = 0; + else if ( col->replace==REPLACE_NON_MISSING ) { if ( ori[0]==bcf_int32_missing ) use_new_ann = 0; } + else if ( col->replace==REPLACE_MISSING ) { if ( ori[0]!=bcf_int32_missing ) use_new_ann = 0; } + else if ( col->replace==REPLACE_ALL ) { if ( ann[0]==bcf_int32_missing ) use_new_ann = 0; } + if ( !use_new_ann ) + { + for (j=0; jhdr_out,line,col->hdr_key_dst,args->tmpi3,nvals*bcf_hdr_nsamples(args->hdr_out)); + } +} +static int core_setter_format_real(args_t *args, bcf1_t *line, annot_col_t *col, float *vals, int nvals) +{ + if ( !args->sample_map ) + return bcf_update_format_float(args->hdr_out,line,col->hdr_key_dst,vals,nvals*args->nsmpl_annot); + + int i, j, ndst = bcf_get_format_float(args->hdr,line,col->hdr_key_dst,&args->tmpf2,&args->mtmpf2); + if ( ndst > 0 ) ndst /= bcf_hdr_nsamples(args->hdr_out); + if ( ndst<=0 ) + { + if ( col->replace==REPLACE_NON_MISSING ) return 0; // overwrite only if present + hts_expand(float, nvals*bcf_hdr_nsamples(args->hdr_out), args->mtmpf2, args->tmpf2); + for (i=0; ihdr_out); i++) + { + float *dst = args->tmpf2 + nvals*i; + if ( args->sample_map[i]==-1 ) + { + bcf_float_set_missing(dst[0]); + for (j=1; jsample_map[i]; + for (j=0; jhdr_out,line,col->hdr_key_dst,args->tmpf2,nvals*bcf_hdr_nsamples(args->hdr_out)); + } + else if ( ndst >= nvals ) + { + for (i=0; ihdr_out); i++) + { + if ( args->sample_map[i]==-1 ) continue; + float *src = vals + nvals*args->sample_map[i]; + float *dst = args->tmpf2 + ndst*i; + if ( col->replace==REPLACE_NON_MISSING ) { if ( bcf_float_is_missing(dst[0]) ) continue; } + else if ( col->replace==REPLACE_MISSING ) { if ( !bcf_float_is_missing(dst[0]) ) continue; } + else if ( col->replace==REPLACE_ALL ) { if ( bcf_float_is_missing(src[0]) ) continue; } + for (j=0; jhdr_out,line,col->hdr_key_dst,args->tmpf2,ndst*bcf_hdr_nsamples(args->hdr_out)); + } + else // ndst < nvals + { + hts_expand(float, nvals*bcf_hdr_nsamples(args->hdr_out), args->mtmpf3, args->tmpf3); + for (i=0; ihdr_out); i++) + { + float *ann = vals + nvals*args->sample_map[i]; + float *ori = args->tmpf2 + ndst*i; // ori vcf line + float *dst = args->tmpf3 + nvals*i; // expanded buffer + int use_new_ann = 1; + if ( args->sample_map[i]==-1 ) use_new_ann = 0; + else if ( col->replace==REPLACE_NON_MISSING ) { if ( bcf_float_is_missing(ori[0]) ) use_new_ann = 0; } + else if ( col->replace==REPLACE_MISSING ) { if ( !bcf_float_is_missing(ori[0]) ) use_new_ann = 0; } + else if ( col->replace==REPLACE_ALL ) { if ( bcf_float_is_missing(ann[0]) ) use_new_ann = 0; } + if ( !use_new_ann ) + { + for (j=0; jhdr_out,line,col->hdr_key_dst,args->tmpf3,nvals*bcf_hdr_nsamples(args->hdr_out)); + } +} +static int core_setter_format_str(args_t *args, bcf1_t *line, annot_col_t *col, char **vals) +{ + if ( !args->sample_map ) + return bcf_update_format_string(args->hdr_out,line,col->hdr_key_dst,(const char**)vals,args->nsmpl_annot); + + int i; + args->tmpp2[0] = args->tmps2; + int ret = bcf_get_format_string(args->hdr,line,col->hdr_key_dst,&args->tmpp2,&args->mtmps2); + args->tmps2 = args->tmpp2[0]; // tmps2 might be realloced + + int nsmpl = bcf_hdr_nsamples(args->hdr_out); + if ( ret<=0 ) // not present in dst + { + hts_expand(char,bcf_hdr_nsamples(args->hdr_out)*2,args->mtmps2,args->tmps2); + char *tmp = args->tmps2; + for (i=0; itmpp2[i] = tmp; + tmp += 2; + } + } + for (i=0; isample_map[i]==-1 ) continue; + char **src = vals + args->sample_map[i]; + char **dst = args->tmpp2 + i; + + if ( col->replace==REPLACE_NON_MISSING ) { if ( (*dst)[0]=='.' && (*dst)[1]==0 ) continue; } + else if ( col->replace==REPLACE_MISSING ) { if ( (*dst)[0]!='.' || (*dst)[1]!=0 ) continue; } + else if ( col->replace==REPLACE_ALL ) { if ( (*src)[0]=='.' && (*src)[1]==0 ) continue; } + *dst = *src; + } + return bcf_update_format_string(args->hdr_out,line,col->hdr_key_dst,(const char**)args->tmpp2,nsmpl); +} +static int setter_format_int(args_t *args, bcf1_t *line, annot_col_t *col, void *data) +{ + annot_line_t *tab = (annot_line_t*) data; + if ( col->icol+args->nsmpl_annot > tab->ncols ) + error("Incorrect number of values for %s at %s:%d\n",col->hdr_key_src,bcf_seqname(args->hdr,line),line->pos+1); + int nvals = count_vals(tab,col->icol,col->icol+args->nsmpl_annot); + hts_expand(int32_t,nvals*args->nsmpl_annot,args->mtmpi,args->tmpi); + + int icol = col->icol, ismpl; + for (ismpl=0; ismplnsmpl_annot; ismpl++) + { + int32_t *ptr = args->tmpi + ismpl*nvals; + int ival = 0; + + char *str = tab->cols[icol]; + while ( *str ) + { + if ( str[0]=='.' && (!str[1] || str[1]==',') ) // missing value + { + ptr[ival++] = bcf_int32_missing; + str += str[1] ? 2 : 1; + continue; + } + + char *end = str; + ptr[ival] = strtol(str, &end, 10); + if ( end==str ) + error("Could not parse %s at %s:%d .. [%s]\n", col->hdr_key_src,bcf_seqname(args->hdr,line),line->pos+1,tab->cols[col->icol]); + + ival++; + str = *end ? end+1 : end; + } + while ( ivaltmpi,nvals); +} +static int setter_format_real(args_t *args, bcf1_t *line, annot_col_t *col, void *data) +{ + annot_line_t *tab = (annot_line_t*) data; + if ( col->icol+args->nsmpl_annot > tab->ncols ) + error("Incorrect number of values for %s at %s:%d\n",col->hdr_key_src,bcf_seqname(args->hdr,line),line->pos+1); + int nvals = count_vals(tab,col->icol,col->icol+args->nsmpl_annot); + hts_expand(float,nvals*args->nsmpl_annot,args->mtmpf,args->tmpf); + + int icol = col->icol, ismpl; + for (ismpl=0; ismplnsmpl_annot; ismpl++) + { + float *ptr = args->tmpf + ismpl*nvals; + int ival = 0; + + char *str = tab->cols[icol]; + while ( *str ) + { + if ( str[0]=='.' && (!str[1] || str[1]==',') ) // missing value + { + bcf_float_set_missing(ptr[ival]); + ival++; + str += str[1] ? 2 : 1; + continue; + } + + char *end = str; + ptr[ival] = strtod(str, &end); + if ( end==str ) + error("Could not parse %s at %s:%d .. [%s]\n", col->hdr_key_src,bcf_seqname(args->hdr,line),line->pos+1,tab->cols[col->icol]); + + ival++; + str = *end ? end+1 : end; + } + while ( ivaltmpf,nvals); +} +static int setter_format_str(args_t *args, bcf1_t *line, annot_col_t *col, void *data) +{ + annot_line_t *tab = (annot_line_t*) data; + if ( col->icol+args->nsmpl_annot > tab->ncols ) + error("Incorrect number of values for %s at %s:%d\n",col->hdr_key_src,bcf_seqname(args->hdr,line),line->pos+1); + + int ismpl; + for (ismpl=0; ismplnsmpl_annot; ismpl++) + args->tmpp[ismpl] = tab->cols[col->icol + ismpl]; + + return core_setter_format_str(args,line,col,args->tmpp); +} +static int vcf_setter_format_int(args_t *args, bcf1_t *line, annot_col_t *col, void *data) +{ + bcf1_t *rec = (bcf1_t*) data; + int nsrc = bcf_get_format_int32(args->files->readers[1].header,rec,col->hdr_key_src,&args->tmpi,&args->mtmpi); + if ( nsrc==-3 ) return 0; // the tag is not present + if ( nsrc<=0 ) return 1; // error + return core_setter_format_int(args,line,col,args->tmpi,nsrc/bcf_hdr_nsamples(args->files->readers[1].header)); +} +static int vcf_setter_format_real(args_t *args, bcf1_t *line, annot_col_t *col, void *data) +{ + bcf1_t *rec = (bcf1_t*) data; + int nsrc = bcf_get_format_float(args->files->readers[1].header,rec,col->hdr_key_src,&args->tmpf,&args->mtmpf); + if ( nsrc==-3 ) return 0; // the tag is not present + if ( nsrc<=0 ) return 1; // error + return core_setter_format_real(args,line,col,args->tmpf,nsrc/bcf_hdr_nsamples(args->files->readers[1].header)); +} + +static int vcf_setter_format_str(args_t *args, bcf1_t *line, annot_col_t *col, void *data) +{ + bcf1_t *rec = (bcf1_t*) data; + args->tmpp[0] = args->tmps; + int ret = bcf_get_format_string(args->files->readers[1].header,rec,col->hdr_key_src,&args->tmpp,&args->mtmps); + args->tmps = args->tmpp[0]; // tmps might be realloced + if ( ret==-3 ) return 0; // the tag is not present + if ( ret<=0 ) return 1; // error + return core_setter_format_str(args,line,col,args->tmpp); +} +static int init_sample_map(args_t *args, bcf_hdr_t *src, bcf_hdr_t *dst) +{ + int i; + if ( !args->sample_names ) + { + args->nsmpl_annot = bcf_hdr_nsamples(dst); + + // tab annotation file, expecting that all samples are present: sample map not needed + if ( !src ) return 0; + + int nmatch = 0, order_ok = 1; + for (i=0; isamples[i]); + if ( id!=-1 ) + { + nmatch++; + if ( i!=id ) order_ok = 0; + } + } + if ( bcf_hdr_nsamples(src)==bcf_hdr_nsamples(dst) && nmatch==bcf_hdr_nsamples(src) && order_ok ) return 0; // not needed + if ( !nmatch ) return -1; // No matching samples found in the source and the destination file + + args->nsample_map = bcf_hdr_nsamples(dst); + args->sample_map = (int*) malloc(sizeof(int)*args->nsample_map); + for (i=0; insample_map; i++) + { + int id = bcf_hdr_id2int(src, BCF_DT_SAMPLE, dst->samples[i]); + args->sample_map[i] = id; // idst -> isrc, -1 if not present + } + return 1; + } + + args->nsample_map = bcf_hdr_nsamples(dst); + args->sample_map = (int*) malloc(sizeof(int)*args->nsample_map); + for (i=0; insample_map; i++) args->sample_map[i] = -1; + + // possible todo: could do with smpl_ilist only + smpl_ilist_t *ilist = smpl_ilist_init(dst, args->sample_names, args->sample_is_file, SMPL_STRICT); + if ( !ilist || !ilist->n ) error("Could not parse: %s\n", args->sample_names); + char **samples = (char**) malloc(sizeof(char*)*ilist->n); + for (i=0; in; i++) samples[i] = strdup(dst->samples[i]); + args->nsmpl_annot = ilist->n; + smpl_ilist_destroy(ilist); + int need_sample_map = args->nsmpl_annot==bcf_hdr_nsamples(dst) ? 0 : 1; + if ( !src ) + { + // tab annotation file + for (i=0; insmpl_annot; i++) + { + int idst = bcf_hdr_id2int(dst, BCF_DT_SAMPLE, samples[i]); + if ( idst==-1 ) error("Sample \"%s\" not found in the destination file\n", samples[i]); + args->sample_map[idst] = i; + if ( idst!=i ) need_sample_map = 1; + } + } + else + { + // vcf annotation file + for (i=0; insmpl_annot; i++) + { + int isrc, idst; + char *ss = samples[i], *se = samples[i]; + while ( *se && !isspace(*se) ) se++; + if ( !*se ) + { + // only one sample name + isrc = bcf_hdr_id2int(src, BCF_DT_SAMPLE,ss); + if ( isrc==-1 ) error("Sample \"%s\" not found in the source file\n", ss); + idst = bcf_hdr_id2int(dst, BCF_DT_SAMPLE,ss); + if ( idst==-1 ) error("Sample \"%s\" not found in the destination file\n", ss); + args->sample_map[idst] = isrc; + if ( idst!=isrc ) need_sample_map = 1; + continue; + } + *se = 0; + isrc = bcf_hdr_id2int(src, BCF_DT_SAMPLE,ss); + if ( isrc==-1 ) error("Sample \"%s\" not found in the source file\n", ss); + + ss = se+1; + while ( isspace(*ss) ) ss++; + se = ss; + while ( *se && !isspace(*se) ) se++; + + idst = bcf_hdr_id2int(dst, BCF_DT_SAMPLE,ss); + if ( idst==-1 ) error("Sample \"%s\" not found in the destination file\n", ss); + + args->sample_map[idst] = isrc; + if ( idst!=isrc ) need_sample_map = 1; + } + } + for (i=0; insmpl_annot; i++) free(samples[i]); + free(samples); + return need_sample_map; +} +static char *columns_complement(char *columns, void **skip_info, void **skip_fmt) +{ + kstring_t str = {0,0,0}; + char *ss = columns, *se = ss; + while ( *ss ) + { + if ( *se && *se!=',' ) { se++; continue; } + if ( *ss!='^' ) + { + if ( str.l ) kputc(',',&str); + kputsn(ss, se-ss, &str); + if ( !*se ) break; + ss = ++se; + continue; + } + + if ( !strncasecmp("^INFO/",ss,6) ) + { + if ( !*skip_info ) + { + *skip_info = khash_str2int_init(); + if ( str.l ) kputc(',',&str); + kputs("INFO",&str); + } + char tmp = *se; *se = 0; + khash_str2int_inc(*skip_info, strdup(ss+6)); + *se = tmp; + } + else if ( !strncasecmp("^FORMAT/",ss,8) || !strncasecmp("^FMT/",ss,5) ) + { + int n = !strncasecmp("^FMT/",ss,5) ? 5 : 8; + if ( !*skip_fmt ) + { + *skip_fmt = khash_str2int_init(); + if ( str.l ) kputc(',',&str); + kputs("FORMAT",&str); + } + char tmp = *se; *se = 0; + khash_str2int_inc(*skip_fmt, strdup(ss+n)); + *se = tmp; + } + else + { + if ( !*skip_info ) + { + *skip_info = khash_str2int_init(); + if ( str.l ) kputc(',',&str); + kputs("INFO",&str); + } + char tmp = *se; *se = 0; + khash_str2int_inc(*skip_info, strdup(ss+1)); + *se = tmp; + } + + if ( !*se ) break; + ss = ++se; + } + free(columns); + return str.s; +} +static void bcf_hrec_format_rename(bcf_hrec_t *hrec, char *tag, kstring_t *str) +{ + int j, nout = 0; + ksprintf(str, "##%s=<", hrec->key); + for (j=0; jnkeys; j++) + { + if ( !strcmp("IDX",hrec->keys[j]) ) continue; + if ( nout ) kputc(',',str); + if ( !strcmp("ID", hrec->keys[j]) ) + ksprintf(str,"%s=%s", hrec->keys[j], tag); + else + ksprintf(str,"%s=%s", hrec->keys[j], hrec->vals[j]); + nout++; + } + ksprintf(str,">\n"); +} +static void init_columns(args_t *args) +{ + int need_sample_map = 0; + int sample_map_ok = init_sample_map(args, args->tgts_is_vcf?args->files->readers[1].header:NULL, args->hdr); + + void *skip_fmt = NULL, *skip_info = NULL; + if ( args->tgts_is_vcf ) + args->columns = columns_complement(args->columns, &skip_info, &skip_fmt); + + kstring_t str = {0,0,0}, tmp = {0,0,0}; + char *ss = args->columns, *se = ss; + args->ncols = 0; + int icol = -1, has_fmt_str = 0; + while ( *ss ) + { + if ( *se && *se!=',' ) { se++; continue; } + int replace = REPLACE_ALL; + if ( *ss=='+' ) { replace = REPLACE_MISSING; ss++; } + else if ( *ss=='-' ) { replace = REPLACE_NON_MISSING; ss++; } + else if ( *ss=='=' ) { replace = SET_OR_APPEND; ss++; } + icol++; + str.l = 0; + kputsn(ss, se-ss, &str); + if ( !str.s[0] || !strcasecmp("-",str.s) ) ; + else if ( !strcasecmp("CHROM",str.s) ) args->chr_idx = icol; + else if ( !strcasecmp("POS",str.s) ) args->from_idx = icol; + else if ( !strcasecmp("FROM",str.s) ) args->from_idx = icol; + else if ( !strcasecmp("TO",str.s) ) args->to_idx = icol; + else if ( !strcasecmp("REF",str.s) ) args->ref_idx = icol; + else if ( !strcasecmp("ALT",str.s) ) args->alt_idx = icol; + else if ( !strcasecmp("ID",str.s) ) + { + if ( replace==REPLACE_NON_MISSING ) error("Apologies, the -ID feature has not been implemented yet.\n"); + args->ncols++; args->cols = (annot_col_t*) realloc(args->cols,sizeof(annot_col_t)*args->ncols); + annot_col_t *col = &args->cols[args->ncols-1]; + col->icol = icol; + col->replace = replace; + col->setter = args->tgts_is_vcf ? vcf_setter_id : setter_id; + col->hdr_key_src = strdup(str.s); + col->hdr_key_dst = strdup(str.s); + } + else if ( !strcasecmp("FILTER",str.s) ) + { + if ( replace==REPLACE_NON_MISSING ) error("Apologies, the -FILTER feature has not been implemented yet.\n"); + args->ncols++; args->cols = (annot_col_t*) realloc(args->cols,sizeof(annot_col_t)*args->ncols); + annot_col_t *col = &args->cols[args->ncols-1]; + col->icol = icol; + col->replace = replace; + col->setter = args->tgts_is_vcf ? vcf_setter_filter : setter_filter; + col->hdr_key_src = strdup(str.s); + col->hdr_key_dst = strdup(str.s); + if ( args->tgts_is_vcf ) + { + bcf_hdr_t *tgts_hdr = args->files->readers[1].header; + int j; + for (j=0; jnhrec; j++) + { + bcf_hrec_t *hrec = tgts_hdr->hrec[j]; + if ( hrec->type!=BCF_HL_FLT ) continue; + int k = bcf_hrec_find_key(hrec,"ID"); + assert( k>=0 ); // this should always be true for valid VCFs + tmp.l = 0; + bcf_hrec_format(hrec, &tmp); + bcf_hdr_append(args->hdr_out, tmp.s); + } + bcf_hdr_sync(args->hdr_out); + } + } + else if ( !strcasecmp("QUAL",str.s) ) + { + if ( replace==REPLACE_NON_MISSING ) error("Apologies, the -QUAL feature has not been implemented yet.\n"); + if ( replace==SET_OR_APPEND ) error("Apologies, the =QUAL feature has not been implemented yet.\n"); + args->ncols++; args->cols = (annot_col_t*) realloc(args->cols,sizeof(annot_col_t)*args->ncols); + annot_col_t *col = &args->cols[args->ncols-1]; + col->icol = icol; + col->replace = replace; + col->setter = args->tgts_is_vcf ? vcf_setter_qual : setter_qual; + col->hdr_key_src = strdup(str.s); + col->hdr_key_dst = strdup(str.s); + } + else if ( args->tgts_is_vcf && !strcasecmp("INFO",str.s) ) // All INFO fields + { + if ( replace==REPLACE_NON_MISSING ) error("Apologies, the -INFO/TAG feature has not been implemented yet.\n"); + if ( replace==SET_OR_APPEND ) error("Apologies, the =INFO/TAG feature has not been implemented yet.\n"); + bcf_hdr_t *tgts_hdr = args->files->readers[1].header; + int j; + for (j=0; jnhrec; j++) + { + bcf_hrec_t *hrec = tgts_hdr->hrec[j]; + if ( hrec->type!=BCF_HL_INFO ) continue; + int k = bcf_hrec_find_key(hrec,"ID"); + assert( k>=0 ); // this should always be true for valid VCFs + if ( skip_info && khash_str2int_has_key(skip_info,hrec->vals[k]) ) continue; + tmp.l = 0; + bcf_hrec_format(hrec, &tmp); + bcf_hdr_append(args->hdr_out, tmp.s); + bcf_hdr_sync(args->hdr_out); + int hdr_id = bcf_hdr_id2int(args->hdr_out, BCF_DT_ID, hrec->vals[k]); + args->ncols++; args->cols = (annot_col_t*) realloc(args->cols,sizeof(annot_col_t)*args->ncols); + annot_col_t *col = &args->cols[args->ncols-1]; + col->icol = -1; + col->replace = replace; + col->hdr_key_src = strdup(hrec->vals[k]); + col->hdr_key_dst = strdup(hrec->vals[k]); + col->number = bcf_hdr_id2length(args->hdr_out,BCF_HL_INFO,hdr_id); + switch ( bcf_hdr_id2type(args->hdr_out,BCF_HL_INFO,hdr_id) ) + { + case BCF_HT_FLAG: col->setter = vcf_setter_info_flag; break; + case BCF_HT_INT: col->setter = vcf_setter_info_int; break; + case BCF_HT_REAL: col->setter = vcf_setter_info_real; break; + case BCF_HT_STR: col->setter = vcf_setter_info_str; break; + default: error("The type of %s not recognised (%d)\n", str.s,bcf_hdr_id2type(args->hdr_out,BCF_HL_INFO,hdr_id)); + } + } + } + else if ( args->tgts_is_vcf && (!strcasecmp("FORMAT",str.s) || !strcasecmp("FMT",str.s)) ) // All FORMAT fields + { + bcf_hdr_t *tgts_hdr = args->files->readers[1].header; + need_sample_map = 1; + int j; + for (j=0; jnhrec; j++) + { + bcf_hrec_t *hrec = tgts_hdr->hrec[j]; + if ( hrec->type!=BCF_HL_FMT) continue; + int k = bcf_hrec_find_key(hrec,"ID"); + assert( k>=0 ); // this should always be true for valid VCFs + if ( skip_fmt && khash_str2int_has_key(skip_fmt,hrec->vals[k]) ) continue; + tmp.l = 0; + bcf_hrec_format(hrec, &tmp); + bcf_hdr_append(args->hdr_out, tmp.s); + bcf_hdr_sync(args->hdr_out); + int hdr_id = bcf_hdr_id2int(args->hdr_out, BCF_DT_ID, hrec->vals[k]); + args->ncols++; args->cols = (annot_col_t*) realloc(args->cols,sizeof(annot_col_t)*args->ncols); + annot_col_t *col = &args->cols[args->ncols-1]; + col->icol = -1; + col->replace = replace; + col->hdr_key_src = strdup(hrec->vals[k]); + col->hdr_key_dst = strdup(hrec->vals[k]); + if ( !strcasecmp("GT",col->hdr_key_src) ) col->setter = vcf_setter_format_gt; + else + switch ( bcf_hdr_id2type(args->hdr_out,BCF_HL_FMT,hdr_id) ) + { + case BCF_HT_INT: col->setter = vcf_setter_format_int; break; + case BCF_HT_REAL: col->setter = vcf_setter_format_real; break; + case BCF_HT_STR: col->setter = vcf_setter_format_str; has_fmt_str = 1; break; + default: error("The type of %s not recognised (%d)\n", str.s,bcf_hdr_id2type(args->hdr_out,BCF_HL_FMT,hdr_id)); + } + } + } + else if ( !strncasecmp("FORMAT/",str.s, 7) || !strncasecmp("FMT/",str.s,4) ) + { + char *key_dst = str.s + (!strncasecmp("FMT/",str.s,4) ? 4 : 7); + char *key_src = strstr(key_dst,":="); + if ( key_src ) + { + *key_src = 0; + key_src += 2; + if ( !strncasecmp("FORMAT/",key_src,7) ) key_src += 7; + else if ( !strncasecmp("FMT/",key_src,4) ) key_src += 4; + } + else + key_src = key_dst; + need_sample_map = 1; + if ( args->tgts_is_vcf ) + { + bcf_hrec_t *hrec = bcf_hdr_get_hrec(args->files->readers[1].header, BCF_HL_FMT, "ID", key_src, NULL); + tmp.l = 0; + bcf_hrec_format_rename(hrec, key_dst, &tmp); + bcf_hdr_append(args->hdr_out, tmp.s); + bcf_hdr_sync(args->hdr_out); + } + int hdr_id = bcf_hdr_id2int(args->hdr_out, BCF_DT_ID, key_dst); + if ( !bcf_hdr_idinfo_exists(args->hdr_out,BCF_HL_FMT,hdr_id) ) + error("The tag \"%s\" is not defined in %s\n", str.s, args->targets_fname); + args->ncols++; args->cols = (annot_col_t*) realloc(args->cols,sizeof(annot_col_t)*args->ncols); + annot_col_t *col = &args->cols[args->ncols-1]; + if ( !args->tgts_is_vcf ) + { + col->icol = icol; + icol += args->nsmpl_annot - 1; + } + else + col->icol = -1; + col->replace = replace; + col->hdr_key_src = strdup(key_src); + col->hdr_key_dst = strdup(key_dst); + if ( !strcasecmp("GT",key_src) ) col->setter = vcf_setter_format_gt; + else + switch ( bcf_hdr_id2type(args->hdr_out,BCF_HL_FMT,hdr_id) ) + { + case BCF_HT_INT: col->setter = args->tgts_is_vcf ? vcf_setter_format_int : setter_format_int; break; + case BCF_HT_REAL: col->setter = args->tgts_is_vcf ? vcf_setter_format_real : setter_format_real; break; + case BCF_HT_STR: col->setter = args->tgts_is_vcf ? vcf_setter_format_str : setter_format_str; has_fmt_str = 1; break; + default: error("The type of %s not recognised (%d)\n", str.s,bcf_hdr_id2type(args->hdr_out,BCF_HL_FMT,hdr_id)); + } + } + else + { + if ( replace==REPLACE_NON_MISSING ) error("Apologies, the -INFO/TAG feature has not been implemented yet.\n"); + if ( replace==SET_OR_APPEND ) error("Apologies, the =INFO/TAG feature has not been implemented yet.\n"); + char *key_dst = !strncasecmp("INFO/",str.s,5) ? str.s + 5 : str.s; + char *key_src = strstr(key_dst,":="); + if ( key_src ) + { + *key_src = 0; + key_src += 2; + if ( !strncasecmp("INFO/",key_src,5) ) key_src += 5; + } + else + key_src = key_dst; + int hdr_id = bcf_hdr_id2int(args->hdr_out, BCF_DT_ID, key_dst); + if ( !bcf_hdr_idinfo_exists(args->hdr_out,BCF_HL_INFO,hdr_id) ) + { + if ( args->tgts_is_vcf ) // reading annotations from a VCF, add a new header line + { + bcf_hrec_t *hrec = bcf_hdr_get_hrec(args->files->readers[1].header, BCF_HL_INFO, "ID", key_src, NULL); + if ( !hrec ) error("The tag \"%s\" is not defined in %s\n", str.s,args->files->readers[1].fname); + tmp.l = 0; + bcf_hrec_format_rename(hrec, key_dst, &tmp); + bcf_hdr_append(args->hdr_out, tmp.s); + bcf_hdr_sync(args->hdr_out); + hdr_id = bcf_hdr_id2int(args->hdr_out, BCF_DT_ID, key_dst); + } + else + error("The tag \"%s\" is not defined in %s\n", key_src, args->targets_fname); + assert( bcf_hdr_idinfo_exists(args->hdr_out,BCF_HL_INFO,hdr_id) ); + } + + args->ncols++; args->cols = (annot_col_t*) realloc(args->cols,sizeof(annot_col_t)*args->ncols); + annot_col_t *col = &args->cols[args->ncols-1]; + col->icol = icol; + col->replace = replace; + col->hdr_key_src = strdup(key_src); + col->hdr_key_dst = strdup(key_dst); + col->number = bcf_hdr_id2length(args->hdr_out,BCF_HL_INFO,hdr_id); + switch ( bcf_hdr_id2type(args->hdr_out,BCF_HL_INFO,hdr_id) ) + { + case BCF_HT_FLAG: col->setter = args->tgts_is_vcf ? vcf_setter_info_flag : setter_info_flag; break; + case BCF_HT_INT: col->setter = args->tgts_is_vcf ? vcf_setter_info_int : setter_info_int; break; + case BCF_HT_REAL: col->setter = args->tgts_is_vcf ? vcf_setter_info_real : setter_info_real; break; + case BCF_HT_STR: col->setter = args->tgts_is_vcf ? vcf_setter_info_str : setter_info_str; break; + default: error("The type of %s not recognised (%d)\n", str.s,bcf_hdr_id2type(args->hdr_out,BCF_HL_INFO,hdr_id)); + } + } + if ( !*se ) break; + ss = ++se; + } + free(str.s); + free(tmp.s); + if ( args->to_idx==-1 ) args->to_idx = args->from_idx; + free(args->columns); + if ( skip_info ) khash_str2int_destroy_free(skip_info); + if ( skip_fmt ) khash_str2int_destroy_free(skip_fmt); + if ( has_fmt_str ) + { + int n = bcf_hdr_nsamples(args->hdr_out); + if ( args->tgts_is_vcf && nfiles->readers[1].header) ) n = bcf_hdr_nsamples(args->files->readers[1].header); + args->tmpp = (char**)malloc(sizeof(char*)*n); + args->tmpp2 = (char**)malloc(sizeof(char*)*n); + } + if ( !need_sample_map ) + { + free(args->sample_map); + args->sample_map = NULL; + } + else if ( sample_map_ok<0 ) + error("No matching samples in source and destination file?\n"); +} + +static void rename_chrs(args_t *args, char *fname) +{ + int n, i; + char **map = hts_readlist(fname, 1, &n); + if ( !map ) error("Could not read: %s\n", fname); + for (i=0; ihdr_out, map[i]); + bcf_hrec_t *hrec = bcf_hdr_get_hrec(args->hdr_out, BCF_HL_CTG, "ID", map[i], NULL); + if ( !hrec ) continue; // the sequence not present + int j = bcf_hrec_find_key(hrec, "ID"); + assert( j>=0 ); + free(hrec->vals[j]); + ss++; + while ( *ss && isspace(*ss) ) ss++; + char *se = ss; + while ( *se && !isspace(*se) ) se++; + *se = 0; + hrec->vals[j] = strdup(ss); + args->hdr_out->id[BCF_DT_CTG][rid].key = hrec->vals[j]; + } + for (i=0; ihdr = args->files->readers[0].header; + args->hdr_out = bcf_hdr_dup(args->hdr); + + if ( args->remove_annots ) init_remove_annots(args); + if ( args->header_fname ) init_header_lines(args); + if ( args->targets_fname && args->tgts_is_vcf ) + { + // reading annots from a VCF + if ( !bcf_sr_add_reader(args->files, args->targets_fname) ) + error("Failed to open %s: %s\n", args->targets_fname,bcf_sr_strerror(args->files->errnum)); + } + if ( args->columns ) init_columns(args); + if ( args->targets_fname && !args->tgts_is_vcf ) + { + if ( !args->columns ) error("The -c option not given\n"); + if ( args->chr_idx==-1 ) error("The -c CHROM option not given\n"); + if ( args->from_idx==-1 ) error("The -c POS option not given\n"); + if ( args->to_idx==-1 ) args->to_idx = -args->from_idx - 1; + + args->tgts = bcf_sr_regions_init(args->targets_fname,1,args->chr_idx,args->from_idx,args->to_idx); + if ( !args->tgts ) error("Could not initialize the annotation file: %s\n", args->targets_fname); + if ( !args->tgts->tbx ) error("Expected tabix-indexed annotation file: %s\n", args->targets_fname); + } + args->vcmp = vcmp_init(); + + if ( args->filter_str ) + args->filter = filter_init(args->hdr, args->filter_str); + + if ( args->set_ids_fmt ) + { + if ( args->set_ids_fmt[0]=='+' ) { args->set_ids_replace = 0; args->set_ids_fmt++; } + args->set_ids = convert_init(args->hdr_out, NULL, 0, args->set_ids_fmt); + } + + if ( args->mark_sites ) + { + if ( !args->targets_fname ) error("The -a option not given\n"); + bcf_hdr_printf(args->hdr_out,"##INFO=", + args->mark_sites,args->mark_sites_logic==MARK_LISTED?"":"not ",args->mark_sites); + } + + if (args->record_cmd_line) bcf_hdr_append_version(args->hdr_out, args->argc, args->argv, "bcftools_annotate"); + if ( !args->drop_header ) + { + if ( args->rename_chrs ) rename_chrs(args, args->rename_chrs); + + args->out_fh = hts_open(args->output_fname,hts_bcf_wmode(args->output_type)); + if ( args->out_fh == NULL ) error("Can't write to \"%s\": %s\n", args->output_fname, strerror(errno)); + if ( args->n_threads ) + hts_set_opt(args->out_fh, HTS_OPT_THREAD_POOL, args->files->p); + bcf_hdr_write(args->out_fh, args->hdr_out); + } +} + +static void destroy_data(args_t *args) +{ + int i; + for (i=0; inrm; i++) free(args->rm[i].key); + free(args->rm); + if ( args->hdr_out ) bcf_hdr_destroy(args->hdr_out); + if (args->vcmp) vcmp_destroy(args->vcmp); + for (i=0; incols; i++) + { + free(args->cols[i].hdr_key_src); + free(args->cols[i].hdr_key_dst); + } + free(args->cols); + for (i=0; imalines; i++) + { + free(args->alines[i].cols); + free(args->alines[i].als); + free(args->alines[i].line.s); + } + free(args->alines); + if ( args->tgts ) bcf_sr_regions_destroy(args->tgts); + free(args->tmpks.s); + free(args->tmpi); + free(args->tmpf); + free(args->tmps); + free(args->tmpp); + free(args->tmpi2); + free(args->tmpf2); + free(args->tmps2); + free(args->tmpp2); + free(args->tmpi3); + free(args->tmpf3); + if ( args->set_ids ) + convert_destroy(args->set_ids); + if ( args->filter ) + filter_destroy(args->filter); + if (args->out_fh) hts_close(args->out_fh); + free(args->sample_map); +} + +static void buffer_annot_lines(args_t *args, bcf1_t *line, int start_pos, int end_pos) +{ + if ( args->nalines && args->alines[0].rid != line->rid ) args->nalines = 0; + + int i = 0; + while ( inalines ) + { + if ( line->pos > args->alines[i].end ) + { + args->nalines--; + if ( args->nalines && inalines ) + { + annot_line_t tmp = args->alines[i]; + memmove(&args->alines[i],&args->alines[i+1],(args->nalines-i)*sizeof(annot_line_t)); + args->alines[args->nalines] = tmp; + } + } + else i++; + } + + if ( args->ref_idx==-1 && args->nalines ) return; + + while ( !bcf_sr_regions_overlap(args->tgts, bcf_seqname(args->hdr,line), start_pos,end_pos) ) + { + args->nalines++; + hts_expand0(annot_line_t,args->nalines,args->malines,args->alines); + annot_line_t *tmp = &args->alines[args->nalines-1]; + tmp->rid = line->rid; + tmp->start = args->tgts->start; + tmp->end = args->tgts->end; + tmp->line.l = 0; + kputs(args->tgts->line.s, &tmp->line); + char *s = tmp->line.s; + tmp->ncols = 1; + hts_expand(char*,tmp->ncols,tmp->mcols,tmp->cols); + tmp->cols[0] = s; + while ( *s ) + { + if ( *s=='\t' ) + { + tmp->ncols++; + hts_expand(char*,tmp->ncols,tmp->mcols,tmp->cols); + tmp->cols[tmp->ncols-1] = s+1; + *s = 0; + } + s++; + } + if ( args->ref_idx != -1 ) + { + if ( args->ref_idx >= tmp->ncols ) + error("Could not parse the line, expected %d+ columns, found %d:\n\t%s\n",args->ref_idx+1,tmp->ncols,args->tgts->line.s); + if ( args->alt_idx >= tmp->ncols ) + error("Could not parse the line, expected %d+ columns, found %d:\n\t%s\n",args->alt_idx+1,tmp->ncols,args->tgts->line.s); + tmp->nals = 2; + hts_expand(char*,tmp->nals,tmp->mals,tmp->als); + tmp->als[0] = tmp->cols[args->ref_idx]; + tmp->als[1] = s = tmp->cols[args->alt_idx]; + while ( *s ) + { + if ( *s==',' ) + { + tmp->nals++; + hts_expand(char*,tmp->nals,tmp->mals,tmp->als); + tmp->als[tmp->nals-1] = s+1; + *s = 0; + } + s++; + } + int iseq = args->tgts->iseq; + if ( bcf_sr_regions_next(args->tgts)<0 || args->tgts->iseq!=iseq ) break; + } + else break; + } +} + +static void annotate(args_t *args, bcf1_t *line) +{ + int i, j; + for (i=0; inrm; i++) + args->rm[i].handler(args, line, &args->rm[i]); + + if ( args->tgts ) + { + // Buffer annotation lines. When multiple ALT alleles are present in the + // annotation file, at least one must match one of the VCF alleles. + int len = 0; + bcf_get_variant_types(line); + for (i=1; in_allele; i++) + if ( len > line->d.var[i].n ) len = line->d.var[i].n; + int end_pos = len<0 ? line->pos - len : line->pos; + buffer_annot_lines(args, line, line->pos, end_pos); + for (i=0; inalines; i++) + { + if ( line->pos > args->alines[i].end || end_pos < args->alines[i].start ) continue; + if ( args->ref_idx != -1 ) + { + if ( vcmp_set_ref(args->vcmp, line->d.allele[0], args->alines[i].als[0]) < 0 ) continue; // refs not compatible + for (j=1; jalines[i].nals; j++) + { + if ( line->n_allele==1 && args->alines[i].als[j][0]=='.' && args->alines[i].als[j][1]==0 ) break; // no ALT allele in VCF and annot file has "." + if ( vcmp_find_allele(args->vcmp, line->d.allele+1, line->n_allele - 1, args->alines[i].als[j]) >= 0 ) break; + } + if ( j==args->alines[i].nals ) continue; // none of the annot alleles present in VCF's ALT + } + break; + } + + if ( inalines ) + { + // there is a matching line + for (j=0; jncols; j++) + if ( args->cols[j].setter(args,line,&args->cols[j],&args->alines[i]) ) + error("fixme: Could not set %s at %s:%d\n", args->cols[j].hdr_key_src,bcf_seqname(args->hdr,line),line->pos+1); + + } + + if ( args->mark_sites ) + { + // ideally, we'd like to be far more general than this in future, see https://github.com/samtools/bcftools/issues/87 + if ( args->mark_sites_logic==MARK_LISTED ) + bcf_update_info_flag(args->hdr_out,line,args->mark_sites,NULL,inalines?1:0); + else + bcf_update_info_flag(args->hdr_out,line,args->mark_sites,NULL,inalines?0:1); + } + } + else if ( args->files->nreaders == 2 ) + { + if ( bcf_sr_has_line(args->files,1) ) + { + bcf1_t *aline = bcf_sr_get_line(args->files,1); + for (j=0; jncols; j++) + if ( args->cols[j].setter(args,line,&args->cols[j],aline) ) + error("fixme: Could not set %s at %s:%d\n", args->cols[j].hdr_key_src,bcf_seqname(args->hdr,line),line->pos+1); + + if ( args->mark_sites ) + bcf_update_info_flag(args->hdr_out,line,args->mark_sites,NULL,args->mark_sites_logic==MARK_LISTED ? 1 : 0); + } + else if ( args->mark_sites ) + bcf_update_info_flag(args->hdr_out,line,args->mark_sites,NULL, args->mark_sites_logic==MARK_UNLISTED ? 1 : 0); + } + if ( args->set_ids ) + { + args->tmpks.l = 0; + convert_line(args->set_ids, line, &args->tmpks); + if ( args->tmpks.l ) + { + int replace = 0; + if ( args->set_ids_replace ) replace = 1; + else if ( !line->d.id || (line->d.id[0]=='.' && !line->d.id[1]) ) replace = 1; + if ( replace ) + bcf_update_id(args->hdr_out,line,args->tmpks.s); + } + } +} + +static void usage(args_t *args) +{ + fprintf(stderr, "\n"); + fprintf(stderr, "About: Annotate and edit VCF/BCF files.\n"); + fprintf(stderr, "Usage: bcftools annotate [options] \n"); + fprintf(stderr, "\n"); + fprintf(stderr, "Options:\n"); + fprintf(stderr, " -a, --annotations VCF file or tabix-indexed file with annotations: CHR\\tPOS[\\tVALUE]+\n"); + fprintf(stderr, " --collapse matching records by , see man page for details [some]\n"); + fprintf(stderr, " -c, --columns list of columns in the annotation file, e.g. CHROM,POS,REF,ALT,-,INFO/TAG. See man page for details\n"); + fprintf(stderr, " -e, --exclude exclude sites for which the expression is true (see man page for details)\n"); + fprintf(stderr, " -h, --header-lines lines which should be appended to the VCF header\n"); + fprintf(stderr, " -I, --set-id [+] set ID column, see man page for details\n"); + fprintf(stderr, " -i, --include select sites for which the expression is true (see man page for details)\n"); + fprintf(stderr, " -m, --mark-sites [+-] add INFO/tag flag to sites which are (\"+\") or are not (\"-\") listed in the -a file\n"); + fprintf(stderr, " --no-version do not append version and command line to the header\n"); + fprintf(stderr, " -o, --output write output to a file [standard output]\n"); + fprintf(stderr, " -O, --output-type b: compressed BCF, u: uncompressed BCF, z: compressed VCF, v: uncompressed VCF [v]\n"); + fprintf(stderr, " -r, --regions restrict to comma-separated list of regions\n"); + fprintf(stderr, " -R, --regions-file restrict to regions listed in a file\n"); + fprintf(stderr, " --rename-chrs rename sequences according to map file: from\\tto\n"); + fprintf(stderr, " -s, --samples [^] comma separated list of samples to annotate (or exclude with \"^\" prefix)\n"); + fprintf(stderr, " -S, --samples-file [^] file of samples to annotate (or exclude with \"^\" prefix)\n"); + fprintf(stderr, " -x, --remove list of annotations to remove (e.g. ID,INFO/DP,FORMAT/DP,FILTER). See man page for details\n"); + fprintf(stderr, " --threads number of extra output compression threads [0]\n"); + fprintf(stderr, "\n"); + exit(1); +} + +int main_vcfannotate(int argc, char *argv[]) +{ + int c; + args_t *args = (args_t*) calloc(1,sizeof(args_t)); + args->argc = argc; args->argv = argv; + args->files = bcf_sr_init(); + args->output_fname = "-"; + args->output_type = FT_VCF; + args->n_threads = 0; + args->record_cmd_line = 1; + args->ref_idx = args->alt_idx = args->chr_idx = args->from_idx = args->to_idx = -1; + args->set_ids_replace = 1; + int regions_is_file = 0, collapse = 0; + + static struct option loptions[] = + { + {"mark-sites",required_argument,NULL,'m'}, + {"set-id",required_argument,NULL,'I'}, + {"output",required_argument,NULL,'o'}, + {"output-type",required_argument,NULL,'O'}, + {"threads",required_argument,NULL,9}, + {"annotations",required_argument,NULL,'a'}, + {"collapse",required_argument,NULL,2}, + {"include",required_argument,NULL,'i'}, + {"exclude",required_argument,NULL,'e'}, + {"regions",required_argument,NULL,'r'}, + {"regions-file",required_argument,NULL,'R'}, + {"remove",required_argument,NULL,'x'}, + {"columns",required_argument,NULL,'c'}, + {"rename-chrs",required_argument,NULL,1}, + {"header-lines",required_argument,NULL,'h'}, + {"samples",required_argument,NULL,'s'}, + {"samples-file",required_argument,NULL,'S'}, + {"no-version",no_argument,NULL,8}, + {NULL,0,NULL,0} + }; + while ((c = getopt_long(argc, argv, "h:?o:O:r:R:a:x:c:i:e:S:s:I:m:",loptions,NULL)) >= 0) + { + switch (c) { + case 'm': + args->mark_sites_logic = MARK_LISTED; + if ( optarg[0]=='+' ) args->mark_sites = optarg+1; + else if ( optarg[0]=='-' ) { args->mark_sites = optarg+1; args->mark_sites_logic = MARK_UNLISTED; } + else args->mark_sites = optarg; + break; + case 'I': args->set_ids_fmt = optarg; break; + case 's': args->sample_names = optarg; break; + case 'S': args->sample_names = optarg; args->sample_is_file = 1; break; + case 'c': args->columns = strdup(optarg); break; + case 'o': args->output_fname = optarg; break; + case 'O': + switch (optarg[0]) { + case 'b': args->output_type = FT_BCF_GZ; break; + case 'u': args->output_type = FT_BCF; break; + case 'z': args->output_type = FT_VCF_GZ; break; + case 'v': args->output_type = FT_VCF; break; + default: error("The output type \"%s\" not recognised\n", optarg); + }; + break; + case 'e': args->filter_str = optarg; args->filter_logic |= FLT_EXCLUDE; break; + case 'i': args->filter_str = optarg; args->filter_logic |= FLT_INCLUDE; break; + case 'x': args->remove_annots = optarg; break; + case 'a': args->targets_fname = optarg; break; + case 'r': args->regions_list = optarg; break; + case 'R': args->regions_list = optarg; regions_is_file = 1; break; + case 'h': args->header_fname = optarg; break; + case 1 : args->rename_chrs = optarg; break; + case 2 : + if ( !strcmp(optarg,"snps") ) collapse |= COLLAPSE_SNPS; + else if ( !strcmp(optarg,"indels") ) collapse |= COLLAPSE_INDELS; + else if ( !strcmp(optarg,"both") ) collapse |= COLLAPSE_SNPS | COLLAPSE_INDELS; + else if ( !strcmp(optarg,"any") ) collapse |= COLLAPSE_ANY; + else if ( !strcmp(optarg,"all") ) collapse |= COLLAPSE_ANY; + else if ( !strcmp(optarg,"some") ) collapse |= COLLAPSE_SOME; + else if ( !strcmp(optarg,"none") ) collapse = COLLAPSE_NONE; + else error("The --collapse string \"%s\" not recognised.\n", optarg); + break; + case 9 : args->n_threads = strtol(optarg, 0, 0); break; + case 8 : args->record_cmd_line = 0; break; + case '?': usage(args); break; + default: error("Unknown argument: %s\n", optarg); + } + } + + char *fname = NULL; + if ( optind>=argc ) + { + if ( !isatty(fileno((FILE *)stdin)) ) fname = "-"; // reading from stdin + else usage(args); + } + else fname = argv[optind]; + + if ( args->regions_list ) + { + if ( bcf_sr_set_regions(args->files, args->regions_list, regions_is_file)<0 ) + error("Failed to read the regions: %s\n", args->regions_list); + } + if ( args->targets_fname ) + { + htsFile *fp = hts_open(args->targets_fname,"r"); + htsFormat type = *hts_get_format(fp); + hts_close(fp); + + if ( type.format==vcf || type.format==bcf ) + { + args->tgts_is_vcf = 1; + args->files->require_index = 1; + args->files->collapse = collapse ? collapse : COLLAPSE_SOME; + } + } + if ( bcf_sr_set_threads(args->files, args->n_threads)<0 ) error("Failed to create threads\n"); + if ( !bcf_sr_add_reader(args->files, fname) ) error("Failed to open %s: %s\n", fname,bcf_sr_strerror(args->files->errnum)); + + init_data(args); + while ( bcf_sr_next_line(args->files) ) + { + if ( !bcf_sr_has_line(args->files,0) ) continue; + bcf1_t *line = bcf_sr_get_line(args->files,0); + if ( line->errcode ) error("Encountered error, cannot proceed. Please check the error output above.\n"); + if ( args->filter ) + { + int pass = filter_test(args->filter, line, NULL); + if ( args->filter_logic & FLT_EXCLUDE ) pass = pass ? 0 : 1; + if ( !pass ) continue; + } + annotate(args, line); + bcf_write1(args->out_fh, args->hdr_out, line); + } + destroy_data(args); + bcf_sr_destroy(args->files); + free(args); + return 0; +} diff --git a/vcfcall.c b/vcfcall.c new file mode 100644 index 0000000..00771f7 --- /dev/null +++ b/vcfcall.c @@ -0,0 +1,869 @@ +/* vcfcall.c -- SNP/indel variant calling from VCF/BCF. + + Copyright (C) 2013-2016 Genome Research Ltd. + + Author: Petr Danecek + +Permission is hereby granted, free of charge, to any person obtaining a copy +of this software and associated documentation files (the "Software"), to deal +in the Software without restriction, including without limitation the rights +to use, copy, modify, merge, publish, distribute, sublicense, and/or sell +copies of the Software, and to permit persons to whom the Software is +furnished to do so, subject to the following conditions: + +The above copyright notice and this permission notice shall be included in +all copies or substantial portions of the Software. + +THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE +AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER +LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, +OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN +THE SOFTWARE. */ + +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include "bcftools.h" +#include "call.h" +#include "prob1.h" +#include "ploidy.h" +#include "gvcf.h" + +void error(const char *format, ...); + +#ifdef _WIN32 +#define srand48(x) srand(x) +#define lrand48() rand() +#endif + +#define CF_NO_GENO 1 +#define CF_INS_MISSED (1<<1) +#define CF_CCALL (1<<2) +// (1<<3) +// (1<<4) +// (1<<5) +#define CF_ACGT_ONLY (1<<6) +#define CF_QCALL (1<<7) +#define CF_ADJLD (1<<8) +#define CF_NO_INDEL (1<<9) +#define CF_ANNO_MAX (1<<10) +#define CF_MCALL (1<<11) +#define CF_PAIRCALL (1<<12) +#define CF_QCNT (1<<13) +#define CF_INDEL_ONLY (1<<14) + +typedef struct +{ + int flag; // combination of CF_* flags above + int output_type, n_threads, record_cmd_line; + htsFile *bcf_in, *out_fh; + char *bcf_fname, *output_fname; + char **samples; // for subsampling and ploidy + int nsamples, *samples_map; // mapping from output sample names to original VCF + char *regions, *targets; // regions to process + int regions_is_file, targets_is_file; + + char *samples_fname; + int samples_is_file; + int *sample2sex; // mapping for ploidy. If negative, interpreted as -1*ploidy + int *sex2ploidy, *sex2ploidy_prev, nsex; + ploidy_t *ploidy; + gvcf_t *gvcf; + + bcf1_t *missed_line; + call_t aux; // parameters and temporary data + + int argc; + char **argv; + + // int flag, prior_type, n1, n_sub, *sublist, n_perm; + // uint32_t *trio_aux; + // char *prior_file, **subsam; + // uint8_t *ploidy; + // double theta, pref, indel_frac, min_smpl_frac, min_lrt; + // Permutation tests + // int n_perm, *seeds; + // double min_perm_p; + // void *bed; +} +args_t; + +static char **add_sample(void *name2idx, char **lines, int *nlines, int *mlines, char *name, char sex, int *ith) +{ + int ret = khash_str2int_get(name2idx, name, ith); + if ( ret==0 ) return lines; + + hts_expand(char*,(*nlines+1),*mlines,lines); + int len = strlen(name); + lines[*nlines] = (char*) malloc(len+3); + memcpy(lines[*nlines],name,len); + lines[*nlines][len] = ' '; + lines[*nlines][len+1] = sex; + lines[*nlines][len+2] = 0; + *ith = *nlines; + (*nlines)++; + khash_str2int_set(name2idx, strdup(name), *ith); + return lines; +} + +typedef struct +{ + const char *alias, *about, *ploidy; +} +ploidy_predef_t; + +static ploidy_predef_t ploidy_predefs[] = +{ + { .alias = "GRCh37", + .about = "Human Genome reference assembly GRCh37 / hg19", + .ploidy = + "X 1 60000 M 1\n" + "X 2699521 154931043 M 1\n" + "Y 1 59373566 M 1\n" + "Y 1 59373566 F 0\n" + "MT 1 16569 M 1\n" + "MT 1 16569 F 1\n" + "chrX 1 60000 M 1\n" + "chrX 2699521 154931043 M 1\n" + "chrY 1 59373566 M 1\n" + "chrY 1 59373566 F 0\n" + "chrM 1 16569 M 1\n" + "chrM 1 16569 F 1\n" + "* * * M 2\n" + "* * * F 2\n" + }, + { .alias = "GRCh38", + .about = "Human Genome reference assembly GRCh38 / hg38", + .ploidy = + "X 1 9999 M 1\n" + "X 2781480 155701381 M 1\n" + "Y 1 57227415 M 1\n" + "Y 1 57227415 F 0\n" + "MT 1 16569 M 1\n" + "MT 1 16569 F 1\n" + "chrX 1 9999 M 1\n" + "chrX 2781480 155701381 M 1\n" + "chrY 1 57227415 M 1\n" + "chrY 1 57227415 F 0\n" + "chrM 1 16569 M 1\n" + "chrM 1 16569 F 1\n" + "* * * M 2\n" + "* * * F 2\n" + }, + { .alias = "X", + .about = "Treat male samples as haploid and female as diploid regardless of the chromosome name", + .ploidy = + "* * * M 1\n" + "* * * F 2\n" + }, + { .alias = "Y", + .about = "Treat male samples as haploid and female as no-copy, regardless of the chromosome name", + .ploidy = + "* * * M 1\n" + "* * * F 0\n" + }, + { .alias = "1", + .about = "Treat all samples as haploid", + .ploidy = + "* * * * 1\n" + }, + { + .alias = NULL, + .about = NULL, + .ploidy = NULL, + } +}; + +// only 5 columns are required and the first is ignored: +// ignored,sample,father(or 0),mother(or 0),sex(1=M,2=F) +static char **parse_ped_samples(call_t *call, char **vals, int nvals, int *nsmpl) +{ + int i, j, mlines = 0, nlines = 0; + kstring_t str = {0,0,0}, fam_str = {0,0,0}; + void *name2idx = khash_str2int_init(); + char **lines = NULL; + for (i=0; infams++; + hts_expand(family_t, call->nfams, call->mfams, call->fams); + family_t *fam = &call->fams[call->nfams-1]; + fam_str.l = 0; + ksprintf(&fam_str,"father=%s, mother=%s, child=%s", col_ends[1]+1,col_ends[2]+1,col_ends[0]+1); + fam->name = strdup(fam_str.s); + + if ( !khash_str2int_has_key(name2idx, col_ends[1]+1) ) + lines = add_sample(name2idx, lines, &nlines, &mlines, col_ends[1]+1, 'M', &fam->sample[FATHER]); + if ( !khash_str2int_has_key(name2idx, col_ends[2]+1) ) + lines = add_sample(name2idx, lines, &nlines, &mlines, col_ends[2]+1, 'F', &fam->sample[MOTHER]); + + khash_str2int_get(name2idx, col_ends[0]+1, &fam->sample[CHILD]); + khash_str2int_get(name2idx, col_ends[1]+1, &fam->sample[FATHER]); + khash_str2int_get(name2idx, col_ends[2]+1, &fam->sample[MOTHER]); + } + } + free(str.s); + free(fam_str.s); + khash_str2int_destroy_free(name2idx); + + if ( i!=nvals ) // not a ped file + { + if ( i>0 ) error("Could not parse samples, not a PED format.\n"); + return NULL; + } + *nsmpl = nlines; + return lines; +} + + +/* + * Reads sample names and their ploidy (optional) from a file. + * Alternatively, if no such file exists, the file name is interpreted + * as a comma-separated list of samples. When ploidy is not present, + * the default ploidy 2 is assumed. + */ +static void set_samples(args_t *args, const char *fn, int is_file) +{ + int i, nlines; + char **lines = hts_readlist(fn, is_file, &nlines); + if ( !lines ) error("Could not read the file: %s\n", fn); + + int nsmpls; + char **smpls = parse_ped_samples(&args->aux, lines, nlines, &nsmpls); + if ( smpls ) + { + for (i=0; isamples_map = (int*) malloc(sizeof(int)*bcf_hdr_nsamples(args->aux.hdr)); // for subsetting + args->sample2sex = (int*) malloc(sizeof(int)*bcf_hdr_nsamples(args->aux.hdr)); + int dflt_sex_id = ploidy_nsex(args->ploidy) - 1; + for (i=0; iaux.hdr); i++) args->sample2sex[i] = dflt_sex_id; + + int *old2new = (int*) malloc(sizeof(int)*bcf_hdr_nsamples(args->aux.hdr)); + for (i=0; iaux.hdr); i++) old2new[i] = -1; + + int nsmpl = 0, map_needed = 0; + for (i=0; iaux.hdr, BCF_DT_SAMPLE, ss); + if ( ismpl < 0 ) { fprintf(stderr,"Warning: No such sample in the VCF: %s\n",ss); continue; } + if ( old2new[ismpl] != -1 ) { fprintf(stderr,"Warning: The sample is listed multiple times: %s\n",ss); continue; } + + ss = se+1; + while ( *ss && isspace(*ss) ) ss++; + if ( !*ss ) ss = "2"; // default ploidy + se = ss; + while ( *se && !isspace(*se) ) se++; + if ( se==ss ) { *xptr = x; error("Could not parse: \"%s\"\n", lines[i]); } + + if ( ss[1]==0 && (ss[0]=='0' || ss[0]=='1' || ss[0]=='2') ) + args->sample2sex[nsmpl] = -1*(ss[0]-'0'); + else + args->sample2sex[nsmpl] = ploidy_add_sex(args->ploidy, ss); + + if ( ismpl!=nsmpl ) map_needed = 1; + args->samples_map[nsmpl] = ismpl; + old2new[ismpl] = nsmpl; + nsmpl++; + } + + for (i=0; iaux.nfams; i++) + { + int j, nmiss = 0; + family_t *fam = &args->aux.fams[i]; + for (j=0; j<3; j++) + { + fam->sample[i] = old2new[fam->sample[i]]; + if ( fam->sample[i]<0 ) nmiss++; + } + assert( nmiss==0 || nmiss==3 ); + } + free(old2new); + + if ( !map_needed ) { free(args->samples_map); args->samples_map = NULL; } + + args->nsamples = nsmpl; + args->samples = lines; +} + +static void init_missed_line(args_t *args) +{ + int i; + for (i=0; iaux.hdr); i++) + { + args->aux.gts[i*2] = bcf_gt_missing; + args->aux.gts[i*2+1] = bcf_int32_vector_end; + } + args->missed_line = bcf_init1(); + bcf_update_genotypes(args->aux.hdr, args->missed_line, args->aux.gts, 2*bcf_hdr_nsamples(args->aux.hdr)); + bcf_float_set_missing(args->missed_line->qual); +} + +static void print_missed_line(bcf_sr_regions_t *regs, void *data) +{ + args_t *args = (args_t*) data; + call_t *call = &args->aux; + bcf1_t *missed = args->missed_line; + + char *ss = regs->line.s; + int i = 0; + while ( iaux.srs->targets_als-1 && *ss ) + { + if ( *ss=='\t' ) i++; + ss++; + } + if ( !*ss ) error("Could not parse: [%s] (%d)\n", regs->line.s,args->aux.srs->targets_als); + + missed->rid = bcf_hdr_name2id(call->hdr,regs->seq_names[regs->prev_seq]); + missed->pos = regs->start; + bcf_update_alleles_str(call->hdr, missed,ss); + + bcf_write1(args->out_fh, call->hdr, missed); +} + +static void init_data(args_t *args) +{ + args->aux.srs = bcf_sr_init(); + + // Open files for input and output, initialize structures + if ( args->targets ) + { + if ( bcf_sr_set_targets(args->aux.srs, args->targets, args->targets_is_file, args->aux.flag&CALL_CONSTR_ALLELES ? 3 : 0)<0 ) + error("Failed to read the targets: %s\n", args->targets); + + if ( args->aux.flag&CALL_CONSTR_ALLELES && args->flag&CF_INS_MISSED ) + { + args->aux.srs->targets->missed_reg_handler = print_missed_line; + args->aux.srs->targets->missed_reg_data = args; + } + } + if ( args->regions ) + { + if ( bcf_sr_set_regions(args->aux.srs, args->regions, args->regions_is_file)<0 ) + error("Failed to read the regions: %s\n", args->regions); + } + + if ( !bcf_sr_add_reader(args->aux.srs, args->bcf_fname) ) error("Failed to open %s: %s\n", args->bcf_fname,bcf_sr_strerror(args->aux.srs->errnum)); + args->aux.hdr = bcf_sr_get_header(args->aux.srs,0); + + int i; + if ( args->samples_fname ) + { + set_samples(args, args->samples_fname, args->samples_is_file); + if ( args->aux.flag&CALL_CONSTR_TRIO ) + { + if ( 3*args->aux.nfams!=args->nsamples ) error("Expected only trios in %s, sorry!\n", args->samples_fname); + fprintf(stderr,"Detected %d samples in %d trio families\n", args->nsamples,args->aux.nfams); + } + } + if ( args->ploidy ) + { + args->nsex = ploidy_nsex(args->ploidy); + args->sex2ploidy = (int*) calloc(args->nsex,sizeof(int)); + args->sex2ploidy_prev = (int*) calloc(args->nsex,sizeof(int)); + if ( !args->nsamples ) + { + args->nsamples = bcf_hdr_nsamples(args->aux.hdr); + args->sample2sex = (int*) malloc(sizeof(int)*args->nsamples); + for (i=0; insamples; i++) args->sample2sex[i] = args->nsex - 1; + } + } + if ( args->nsamples ) + { + args->aux.ploidy = (uint8_t*) malloc(args->nsamples); + for (i=0; insamples; i++) args->aux.ploidy[i] = ploidy_max(args->ploidy); + for (i=0; insex; i++) args->sex2ploidy_prev[i] = ploidy_max(args->ploidy); + for (i=0; insamples; i++) + if ( args->sample2sex[i] >= args->nsex ) args->sample2sex[i] = args->nsex - 1; + } + + if ( args->gvcf ) + { + int id = bcf_hdr_id2int(args->aux.hdr,BCF_DT_ID,"DP"); + if ( id<0 || !bcf_hdr_idinfo_exists(args->aux.hdr,BCF_HL_FMT,id) ) error("--gvcf output mode requires FORMAT/DP tag, which is not present in the input header\n"); + gvcf_update_header(args->gvcf, args->aux.hdr); + } + + if ( args->samples_map ) + { + args->aux.hdr = bcf_hdr_subset(bcf_sr_get_header(args->aux.srs,0), args->nsamples, args->samples, args->samples_map); + if ( !args->aux.hdr ) error("Error occurred while subsetting samples\n"); + for (i=0; insamples; i++) + if ( args->samples_map[i]<0 ) error("No such sample: %s\n", args->samples[i]); + if ( !bcf_hdr_nsamples(args->aux.hdr) ) error("No matching sample found\n"); + } + else + { + args->aux.hdr = bcf_hdr_dup(bcf_sr_get_header(args->aux.srs,0)); + if ( args->samples ) + { + for (i=0; insamples; i++) + if ( bcf_hdr_id2int(args->aux.hdr,BCF_DT_SAMPLE,args->samples[i])<0 ) + error("No such sample: %s\n", args->samples[i]); + } + } + + args->out_fh = hts_open(args->output_fname, hts_bcf_wmode(args->output_type)); + if ( args->out_fh == NULL ) error("Can't write to \"%s\": %s\n", args->output_fname, strerror(errno)); + if ( args->n_threads ) hts_set_threads(args->out_fh, args->n_threads); + + if ( args->flag & CF_QCALL ) + return; + + if ( args->flag & CF_MCALL ) + mcall_init(&args->aux); + + if ( args->flag & CF_CCALL ) + ccall_init(&args->aux); + + bcf_hdr_remove(args->aux.hdr, BCF_HL_INFO, "QS"); + bcf_hdr_remove(args->aux.hdr, BCF_HL_INFO, "I16"); + + if (args->record_cmd_line) bcf_hdr_append_version(args->aux.hdr, args->argc, args->argv, "bcftools_call"); + bcf_hdr_write(args->out_fh, args->aux.hdr); + + if ( args->flag&CF_INS_MISSED ) init_missed_line(args); +} + +static void destroy_data(args_t *args) +{ + if ( args->flag & CF_CCALL ) ccall_destroy(&args->aux); + else if ( args->flag & CF_MCALL ) mcall_destroy(&args->aux); + else if ( args->flag & CF_QCALL ) qcall_destroy(&args->aux); + int i; + if ( args->samples ) + { + for (i=0; insamples; i++) free(args->samples[i]); + } + if ( args->aux.fams ) + { + for (i=0; iaux.nfams; i++) free(args->aux.fams[i].name); + free(args->aux.fams); + } + if ( args->missed_line ) bcf_destroy(args->missed_line); + ploidy_destroy(args->ploidy); + free(args->sex2ploidy); + free(args->sex2ploidy_prev); + free(args->samples); + free(args->samples_map); + free(args->sample2sex); + free(args->aux.ploidy); + if ( args->gvcf ) gvcf_destroy(args->gvcf); + bcf_hdr_destroy(args->aux.hdr); + hts_close(args->out_fh); + bcf_sr_destroy(args->aux.srs); +} + +void parse_novel_rate(args_t *args, const char *str) +{ + if ( sscanf(str,"%le,%le,%le",&args->aux.trio_Pm_SNPs,&args->aux.trio_Pm_del,&args->aux.trio_Pm_ins)==3 ) // explicit for all + { + args->aux.trio_Pm_SNPs = 1 - args->aux.trio_Pm_SNPs; + args->aux.trio_Pm_del = 1 - args->aux.trio_Pm_del; + args->aux.trio_Pm_ins = 1 - args->aux.trio_Pm_ins; + } + else if ( sscanf(str,"%le,%le",&args->aux.trio_Pm_SNPs,&args->aux.trio_Pm_del)==2 ) // dynamic for indels + { + args->aux.trio_Pm_SNPs = 1 - args->aux.trio_Pm_SNPs; + args->aux.trio_Pm_ins = -1; // negative value for dynamic calculation + } + else if ( sscanf(str,"%le",&args->aux.trio_Pm_SNPs)==1 ) // same for all + { + args->aux.trio_Pm_SNPs = 1 - args->aux.trio_Pm_SNPs; + args->aux.trio_Pm_del = -1; + args->aux.trio_Pm_ins = -1; + } + else error("Could not parse --novel-rate %s\n", str); +} + +static int parse_format_flag(const char *str) +{ + int flag = 0; + const char *ss = str; + while ( *ss ) + { + const char *se = ss; + while ( *se && *se!=',' ) se++; + if ( !strncasecmp(ss,"GQ",se-ss) ) flag |= CALL_FMT_GQ; + else if ( !strncasecmp(ss,"GP",se-ss) ) flag |= CALL_FMT_GP; + else + { + fprintf(stderr,"Could not parse \"%s\"\n", str); + exit(1); + } + if ( !*se ) break; + ss = se + 1; + } + return flag; +} + +static void set_ploidy(args_t *args, bcf1_t *rec) +{ + ploidy_query(args->ploidy,(char*)bcf_seqname(args->aux.hdr,rec),rec->pos,args->sex2ploidy,NULL,NULL); + + int i; + for (i=0; insex; i++) + if ( args->sex2ploidy[i]!=args->sex2ploidy_prev[i] ) break; + + if ( i==args->nsex ) return; // ploidy same as previously + + for (i=0; insamples; i++) + { + if ( args->sample2sex[i]<0 ) + args->aux.ploidy[i] = -1*args->sample2sex[i]; + else + args->aux.ploidy[i] = args->sex2ploidy[args->sample2sex[i]]; + } + int *tmp = args->sex2ploidy; args->sex2ploidy = args->sex2ploidy_prev; args->sex2ploidy_prev = tmp; +} + +ploidy_t *init_ploidy(char *alias) +{ + const ploidy_predef_t *pld = ploidy_predefs; + + int detailed = 0, len = strlen(alias); + if ( alias[len-1]=='?' ) { detailed = 1; alias[len-1] = 0; } + + while ( pld->alias && strcasecmp(alias,pld->alias) ) pld++; + + if ( !pld->alias ) + { + fprintf(stderr,"\nPRE-DEFINED PLOIDY FILES\n\n"); + fprintf(stderr," * Columns are: CHROM,FROM,TO,SEX,PLOIDY\n"); + fprintf(stderr," * Coordinates are 1-based inclusive.\n"); + fprintf(stderr," * A '*' means any value not otherwise defined.\n\n"); + pld = ploidy_predefs; + while ( pld->alias ) + { + fprintf(stderr,"%s\n .. %s\n\n", pld->alias,pld->about); + if ( detailed ) + fprintf(stderr,"%s\n", pld->ploidy); + pld++; + } + fprintf(stderr,"Run as --ploidy (e.g. --ploidy GRCh37).\n"); + fprintf(stderr,"To see the detailed ploidy definition, append a question mark (e.g. --ploidy GRCh37?).\n"); + fprintf(stderr,"\n"); + exit(-1); + } + else if ( detailed ) + { + fprintf(stderr,"%s", pld->ploidy); + exit(-1); + } + return ploidy_init_string(pld->ploidy,2); +} + +static void usage(args_t *args) +{ + fprintf(stderr, "\n"); + fprintf(stderr, "About: SNP/indel variant calling from VCF/BCF. To be used in conjunction with samtools mpileup.\n"); + fprintf(stderr, " This command replaces the former \"bcftools view\" caller. Some of the original\n"); + fprintf(stderr, " functionality has been temporarily lost in the process of transition to htslib,\n"); + fprintf(stderr, " but will be added back on popular demand. The original calling model can be\n"); + fprintf(stderr, " invoked with the -c option.\n"); + fprintf(stderr, "Usage: bcftools call [options] \n"); + fprintf(stderr, "\n"); + fprintf(stderr, "File format options:\n"); + fprintf(stderr, " --no-version do not append version and command line to the header\n"); + fprintf(stderr, " -o, --output write output to a file [standard output]\n"); + fprintf(stderr, " -O, --output-type output type: 'b' compressed BCF; 'u' uncompressed BCF; 'z' compressed VCF; 'v' uncompressed VCF [v]\n"); + fprintf(stderr, " --ploidy [?] predefined ploidy, 'list' to print available settings, append '?' for details\n"); + fprintf(stderr, " --ploidy-file space/tab-delimited list of CHROM,FROM,TO,SEX,PLOIDY\n"); + fprintf(stderr, " -r, --regions restrict to comma-separated list of regions\n"); + fprintf(stderr, " -R, --regions-file restrict to regions listed in a file\n"); + fprintf(stderr, " -s, --samples list of samples to include [all samples]\n"); + fprintf(stderr, " -S, --samples-file PED file or a file with an optional column with sex (see man page for details) [all samples]\n"); + fprintf(stderr, " -t, --targets similar to -r but streams rather than index-jumps\n"); + fprintf(stderr, " -T, --targets-file similar to -R but streams rather than index-jumps\n"); + fprintf(stderr, " --threads number of extra output compression threads [0]\n"); + fprintf(stderr, "\n"); + fprintf(stderr, "Input/output options:\n"); + fprintf(stderr, " -A, --keep-alts keep all possible alternate alleles at variant sites\n"); + fprintf(stderr, " -f, --format-fields output format fields: GQ,GP (lowercase allowed) []\n"); + fprintf(stderr, " -F, --prior-freqs use prior allele frequencies\n"); + fprintf(stderr, " -g, --gvcf ,[...] group non-variant sites into gVCF blocks by minimum per-sample DP\n"); + fprintf(stderr, " -i, --insert-missed output also sites missed by mpileup but present in -T\n"); + fprintf(stderr, " -M, --keep-masked-ref keep sites with masked reference allele (REF=N)\n"); + fprintf(stderr, " -V, --skip-variants skip indels/snps\n"); + fprintf(stderr, " -v, --variants-only output variant sites only\n"); + fprintf(stderr, "\n"); + fprintf(stderr, "Consensus/variant calling options:\n"); + fprintf(stderr, " -c, --consensus-caller the original calling method (conflicts with -m)\n"); + fprintf(stderr, " -C, --constrain one of: alleles, trio (see manual)\n"); + fprintf(stderr, " -m, --multiallelic-caller alternative model for multiallelic and rare-variant calling (conflicts with -c)\n"); + fprintf(stderr, " -n, --novel-rate ,[...] likelihood of novel mutation for constrained trio calling, see man page for details [1e-8,1e-9,1e-9]\n"); + fprintf(stderr, " -p, --pval-threshold variant if P(ref|D) mutation rate (use bigger for greater sensitivity), use with -m [1.1e-3]\n"); + + // todo (and more) + // fprintf(stderr, "\nContrast calling and association test options:\n"); + // fprintf(stderr, " -1 INT number of group-1 samples [0]\n"); + // fprintf(stderr, " -C FLOAT posterior constrast for LRTaux.min_lrt); + // fprintf(stderr, " -U INT number of permutations for association testing (effective with -1) [0]\n"); + // fprintf(stderr, " -X FLOAT only perform permutations for P(chi^2)aux.min_perm_p); + fprintf(stderr, "\n"); + exit(-1); +} + +int main_vcfcall(int argc, char *argv[]) +{ + char *ploidy_fname = NULL, *ploidy = NULL; + args_t args; + memset(&args, 0, sizeof(args_t)); + args.argc = argc; args.argv = argv; + args.aux.prior_type = -1; + args.aux.indel_frac = -1; + args.aux.theta = 1.1e-3; + args.aux.pref = 0.5; + args.aux.min_perm_p = 0.01; + args.aux.min_lrt = 1; + args.flag = CF_ACGT_ONLY; + args.output_fname = "-"; + args.output_type = FT_VCF; + args.n_threads = 0; + args.record_cmd_line = 1; + args.aux.trio_Pm_SNPs = 1 - 1e-8; + args.aux.trio_Pm_ins = args.aux.trio_Pm_del = 1 - 1e-9; + + int c; + static struct option loptions[] = + { + {"help",no_argument,NULL,'h'}, + {"format-fields",required_argument,NULL,'f'}, + {"prior-freqs",required_argument,NULL,'F'}, + {"gvcf",required_argument,NULL,'g'}, + {"output",required_argument,NULL,'o'}, + {"output-type",required_argument,NULL,'O'}, + {"regions",required_argument,NULL,'r'}, + {"regions-file",required_argument,NULL,'R'}, + {"samples",required_argument,NULL,'s'}, + {"samples-file",required_argument,NULL,'S'}, + {"targets",required_argument,NULL,'t'}, + {"targets-file",required_argument,NULL,'T'}, + {"threads",required_argument,NULL,9}, + {"keep-alts",no_argument,NULL,'A'}, + {"insert-missed",no_argument,NULL,'i'}, + {"skip-Ns",no_argument,NULL,'N'}, // now the new default + {"keep-masked-refs",no_argument,NULL,'M'}, + {"skip-variants",required_argument,NULL,'V'}, + {"variants-only",no_argument,NULL,'v'}, + {"consensus-caller",no_argument,NULL,'c'}, + {"constrain",required_argument,NULL,'C'}, + {"multiallelic-caller",no_argument,NULL,'m'}, + {"pval-threshold",required_argument,NULL,'p'}, + {"prior",required_argument,NULL,'P'}, + {"novel-rate",required_argument,NULL,'n'}, + {"ploidy",required_argument,NULL,1}, + {"ploidy-file",required_argument,NULL,2}, + {"chromosome-X",no_argument,NULL,'X'}, + {"chromosome-Y",no_argument,NULL,'Y'}, + {"no-version",no_argument,NULL,8}, + {NULL,0,NULL,0} + }; + + char *tmp = NULL; + while ((c = getopt_long(argc, argv, "h?o:O:r:R:s:S:t:T:ANMV:vcmp:C:n:P:f:ig:XYF:", loptions, NULL)) >= 0) + { + switch (c) + { + case 2 : ploidy_fname = optarg; break; + case 1 : ploidy = optarg; break; + case 'X': ploidy = "X"; fprintf(stderr,"Warning: -X will be deprecated, please use --ploidy instead.\n"); break; + case 'Y': ploidy = "Y"; fprintf(stderr,"Warning: -Y will be deprecated, please use --ploidy instead.\n"); break; + case 'f': args.aux.output_tags |= parse_format_flag(optarg); break; + case 'M': args.flag &= ~CF_ACGT_ONLY; break; // keep sites where REF is N + case 'N': args.flag |= CF_ACGT_ONLY; break; // omit sites where first base in REF is N (the new default) + case 'A': args.aux.flag |= CALL_KEEPALT; break; + case 'c': args.flag |= CF_CCALL; break; // the original EM based calling method + case 'i': args.flag |= CF_INS_MISSED; break; + case 'v': args.aux.flag |= CALL_VARONLY; break; + case 'F': + args.aux.prior_AN = optarg; + args.aux.prior_AC = strchr(optarg,','); + if ( !args.aux.prior_AC ) error("Expected two tags with -F (e.g. AN,AC), got \"%s\"\n",optarg); + *args.aux.prior_AC = 0; + args.aux.prior_AC++; + break; + case 'g': + args.gvcf = gvcf_init(optarg); + if ( !args.gvcf ) error("Could not parse: --gvcf %s\n", optarg); + break; + case 'o': args.output_fname = optarg; break; + case 'O': + switch (optarg[0]) { + case 'b': args.output_type = FT_BCF_GZ; break; + case 'u': args.output_type = FT_BCF; break; + case 'z': args.output_type = FT_VCF_GZ; break; + case 'v': args.output_type = FT_VCF; break; + default: error("The output type \"%s\" not recognised\n", optarg); + } + break; + case 'C': + if ( !strcasecmp(optarg,"alleles") ) args.aux.flag |= CALL_CONSTR_ALLELES; + else if ( !strcasecmp(optarg,"trio") ) args.aux.flag |= CALL_CONSTR_TRIO; + else error("Unknown argument to -C: \"%s\"\n", optarg); + break; + case 'V': + if ( !strcasecmp(optarg,"snps") ) args.flag |= CF_INDEL_ONLY; + else if ( !strcasecmp(optarg,"indels") ) args.flag |= CF_NO_INDEL; + else error("Unknown skip category \"%s\" (-S argument must be \"snps\" or \"indels\")\n", optarg); + break; + case 'm': args.flag |= CF_MCALL; break; // multiallelic calling method + case 'p': + args.aux.pref = strtod(optarg,&tmp); + if ( *tmp ) error("Could not parse: --pval-threshold %s\n", optarg); + break; + case 'P': args.aux.theta = strtod(optarg,&tmp); + if ( *tmp ) error("Could not parse, expected float argument: -P %s\n", optarg); + break; + case 'n': parse_novel_rate(&args,optarg); break; + case 'r': args.regions = optarg; break; + case 'R': args.regions = optarg; args.regions_is_file = 1; break; + case 't': args.targets = optarg; break; + case 'T': args.targets = optarg; args.targets_is_file = 1; break; + case 's': args.samples_fname = optarg; break; + case 'S': args.samples_fname = optarg; args.samples_is_file = 1; break; + case 9 : args.n_threads = strtol(optarg, 0, 0); break; + case 8 : args.record_cmd_line = 0; break; + default: usage(&args); + } + } + // Sanity check options and initialize + if ( ploidy_fname ) args.ploidy = ploidy_init(ploidy_fname, 2); + else if ( ploidy ) args.ploidy = init_ploidy(ploidy); + + if ( optind>=argc ) + { + if ( !isatty(fileno((FILE *)stdin)) ) args.bcf_fname = "-"; // reading from stdin + else usage(&args); + } + else args.bcf_fname = argv[optind++]; + + if ( !ploidy_fname && !ploidy ) + { + if ( !args.samples_is_file ) fprintf(stderr,"Note: none of --samples-file, --ploidy or --ploidy-file given, assuming all sites are diploid\n"); + args.ploidy = ploidy_init_string("* * * 0 0\n* * * 1 1\n* * * 2 2\n",2); + } + + if ( !args.ploidy ) error("Could not initialize ploidy\n"); + if ( (args.flag & CF_CCALL ? 1 : 0) + (args.flag & CF_MCALL ? 1 : 0) + (args.flag & CF_QCALL ? 1 : 0) > 1 ) error("Only one of -c or -m options can be given\n"); + if ( !(args.flag & CF_CCALL) && !(args.flag & CF_MCALL) && !(args.flag & CF_QCALL) ) error("Expected -c or -m option\n"); + if ( (args.flag & CF_CCALL ? 1: 0) && args.gvcf ) error("gvcf -g option not functional with -c calling mode yet\n"); + if ( args.aux.n_perm && args.aux.ngrp1_samples<=0 ) error("Expected -1 with -U\n"); // not sure about this, please fix + if ( args.aux.flag & CALL_CONSTR_ALLELES ) + { + if ( !args.targets ) error("Expected -t or -T with \"-C alleles\"\n"); + if ( !(args.flag & CF_MCALL) ) error("The \"-C alleles\" mode requires -m\n"); + } + if ( args.flag & CF_INS_MISSED && !(args.aux.flag&CALL_CONSTR_ALLELES) ) error("The -i option requires -C alleles\n"); + if ( args.aux.flag&CALL_VARONLY && args.gvcf ) error("The two options cannot be combined: --variants-only and --gvcf\n"); + init_data(&args); + + while ( bcf_sr_next_line(args.aux.srs) ) + { + bcf1_t *bcf_rec = args.aux.srs->readers[0].buffer[0]; + if ( args.samples_map ) bcf_subset(args.aux.hdr, bcf_rec, args.nsamples, args.samples_map); + bcf_unpack(bcf_rec, BCF_UN_STR); + + // Skip unwanted sites + int i, is_indel = bcf_is_snp(bcf_rec) ? 0 : 1; + if ( (args.flag & CF_INDEL_ONLY) && !is_indel ) continue; + if ( (args.flag & CF_NO_INDEL) && is_indel ) continue; + if ( (args.flag & CF_ACGT_ONLY) && (bcf_rec->d.allele[0][0]=='N' || bcf_rec->d.allele[0][0]=='n') ) continue; // REF[0] is 'N' + + // Which allele is symbolic? All SNPs should have it, but not indels + args.aux.unseen = 0; + for (i=1; in_allele; i++) + { + if ( bcf_rec->d.allele[i][0]=='X' ) { args.aux.unseen = i; break; } // old X + if ( bcf_rec->d.allele[i][0]=='<' ) + { + if ( bcf_rec->d.allele[i][1]=='X' && bcf_rec->d.allele[i][2]=='>' ) { args.aux.unseen = i; break; } // old + if ( bcf_rec->d.allele[i][1]=='*' && bcf_rec->d.allele[i][2]=='>' ) { args.aux.unseen = i; break; } // new <*> + } + } + int is_ref = (bcf_rec->n_allele==1 || (bcf_rec->n_allele==2 && args.aux.unseen>0)) ? 1 : 0; + + if ( is_ref && args.aux.flag&CALL_VARONLY ) + continue; + + bcf_unpack(bcf_rec, BCF_UN_ALL); + if ( args.nsex ) set_ploidy(&args, bcf_rec); + + // Various output modes: QCall output (todo) + if ( args.flag & CF_QCALL ) + { + qcall(&args.aux, bcf_rec); + continue; + } + + // Calling modes which output VCFs + int ret; + if ( args.flag & CF_MCALL ) + ret = mcall(&args.aux, bcf_rec); + else + ret = ccall(&args.aux, bcf_rec); + if ( ret==-1 ) error("Something is wrong\n"); + else if ( ret==-2 ) continue; // skip the site + + // Normal output + if ( (args.aux.flag & CALL_VARONLY) && ret==0 && !args.gvcf ) continue; // not a variant + if ( args.gvcf ) + bcf_rec = gvcf_write(args.gvcf, args.out_fh, args.aux.hdr, bcf_rec, ret==1?1:0); + if ( bcf_rec ) + bcf_write1(args.out_fh, args.aux.hdr, bcf_rec); + } + if ( args.gvcf ) gvcf_write(args.gvcf, args.out_fh, args.aux.hdr, NULL, 0); + if ( args.flag & CF_INS_MISSED ) bcf_sr_regions_flush(args.aux.srs->targets); + destroy_data(&args); + return 0; +} + diff --git a/vcfcnv.c b/vcfcnv.c new file mode 100644 index 0000000..ffe71c4 --- /dev/null +++ b/vcfcnv.c @@ -0,0 +1,1412 @@ +/* The MIT License + + Copyright (c) 2014-2015 Genome Research Ltd. + + Author: Petr Danecek + + Permission is hereby granted, free of charge, to any person obtaining a copy + of this software and associated documentation files (the "Software"), to deal + in the Software without restriction, including without limitation the rights + to use, copy, modify, merge, publish, distribute, sublicense, and/or sell + copies of the Software, and to permit persons to whom the Software is + furnished to do so, subject to the following conditions: + + The above copyright notice and this permission notice shall be included in + all copies or substantial portions of the Software. + + THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR + IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, + FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE + AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER + LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, + OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN + THE SOFTWARE. + + */ + +/* + Known issues: + - The --AF-file option behaves like --targets-file, sites not listed in the AFs + are skipped. +*/ + +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include "bcftools.h" +#include "HMM.h" +#include "rbuf.h" + +#define DBG0 0 + +#define N_STATES 4 +#define CN0 0 +#define CN1 1 +#define CN2 2 +#define CN3 3 + +typedef struct +{ + float mean, dev2, norm; +} +gauss_param_t; + +typedef struct +{ + char *name; + int idx; // VCF sample index + float *lrr,*baf, baf_dev2, baf_dev2_dflt, lrr_dev2; + float cell_frac, cell_frac_dflt; + gauss_param_t gauss_param[18]; + double pobs[N_STATES]; + FILE *dat_fh, *cn_fh, *summary_fh; + char *dat_fname, *cn_fname, *summary_fname; +} +sample_t; + +typedef struct _args_t +{ + bcf_srs_t *files; + bcf_hdr_t *hdr; + int prev_rid, ntot, nused; + sample_t query_sample, control_sample; + + int nstates; // number of states: N_STATES for one sample, N_STATES^2 for two samples + double lrr_bias, baf_bias; // LRR/BAF weights + double same_prob, ij_prob; // prior of both samples being the same and the transition probability P(i|j) + double err_prob; // constant probability of erroneous measurement + float *nonref_afs, nonref_af, nonref_af_dflt, fRR, fRA, fAA, *tmpf; + unsigned long int nRR, nRA, nAA; + int mtmpf; + + double *tprob, *tprob_arr; // array of transition matrices, precalculated up to ntprob_arr positions + double *iprobs; // states' initial probabilities + int ntprob_arr; + + hmm_t *hmm; + double *eprob; // emission probs [nstates*nsites,msites] + uint32_t *sites; // positions [nsites,msites] + int nsites, msites; + + double baum_welch_th, optimize_frac; + float plot_th; + FILE *summary_fh; + char **argv, *regions_list, *summary_fname, *output_dir; + char *targets_list, *af_fname; + int argc, verbose, lrr_smooth_win; +} +args_t; + +FILE *open_file(char **fname, const char *mode, const char *fmt, ...); + +static inline void hmm2cn_state(int nstates, int i, int *a, int *b) +{ + *a = i / N_STATES; + *b = i - (*a)*N_STATES; +} +static double *init_tprob_matrix(int ndim, double ij_prob, double same_prob) +{ + int i,j; + double *mat = (double*) malloc(sizeof(double)*ndim*ndim); + + assert( ndim==N_STATES || ndim==N_STATES*N_STATES); + + if ( ndim==N_STATES ) // one sample + { + double pii = 1 - ij_prob*(N_STATES-1); + if ( pii < ij_prob ) error("Error: -x set a bit too high, P(x|x) < P(x|y): %e vs %e\n", pii,ij_prob); + for (j=0; jdat_fh = open_file(&smpl->dat_fname,"w","%s/dat.%s.tab",dir,smpl->name); + smpl->cn_fh = open_file(&smpl->cn_fname,"w","%s/cn.%s.tab",dir,smpl->name); + smpl->summary_fh = open_file(&smpl->summary_fname,"w","%s/summary.%s.tab",dir,smpl->name); + fprintf(smpl->dat_fh,"# [1]Chromosome\t[2]Position\t[3]BAF\t[4]LRR\n"); + fprintf(smpl->cn_fh,"# [1]Chromosome\t[2]Position\t[3]CN\t[4]P(CN0)\t[5]P(CN1)\t[6]P(CN2)\t[7]P(CN3)\n"); + fprintf(smpl->summary_fh,"# RG, Regions [2]Chromosome\t[3]Start\t[4]End\t[5]Copy Number state\t[6]Quality\t[7]nSites\t[8]nHETs\n"); +} +static void close_sample_files(sample_t *smpl) +{ + fclose(smpl->dat_fh); + fclose(smpl->cn_fh); + fclose(smpl->summary_fh); +} + +static double norm_cdf(double mean, double dev); +static void init_data(args_t *args) +{ + args->prev_rid = -1; + args->hdr = args->files->readers[0].header; + + if ( !args->query_sample.name ) + { + if ( bcf_hdr_nsamples(args->hdr)>1 ) error("Multi-sample VCF, missing the -s option\n"); + args->query_sample.name = strdup(args->hdr->samples[0]); + } + else + if ( bcf_hdr_id2int(args->hdr,BCF_DT_SAMPLE,args->query_sample.name)<0 ) error("The sample \"%s\" not found\n", args->query_sample.name); + if ( !args->files->readers[0].file->is_bin ) + { + int ret; + kstring_t tmp = {0,0,0}; + if ( args->control_sample.name ) + { + ksprintf(&tmp, "%s,%s", args->query_sample.name,args->control_sample.name); + ret = bcf_hdr_set_samples(args->hdr, tmp.s, 0); + } + else + { + ret = bcf_hdr_set_samples(args->hdr, args->query_sample.name, 0); + tmp.s = args->query_sample.name; + } + if ( ret<0 ) error("Error parsing the list of samples: %s\n", tmp.s); + else if ( ret>0 ) error("The sample not found in the VCF: %s\n", ret==1 ? args->query_sample.name : args->control_sample.name); + + if ( args->control_sample.name ) free(tmp.s); + } + args->query_sample.idx = bcf_hdr_id2int(args->hdr,BCF_DT_SAMPLE,args->query_sample.name); + args->control_sample.idx = args->control_sample.name ? bcf_hdr_id2int(args->hdr,BCF_DT_SAMPLE,args->control_sample.name) : -1; + args->nstates = args->control_sample.name ? N_STATES*N_STATES : N_STATES; + args->tprob = init_tprob_matrix(args->nstates, args->ij_prob, args->same_prob); + args->iprobs = init_iprobs(args->nstates, args->same_prob); + args->hmm = hmm_init(args->nstates, args->tprob, 10000); + hmm_init_states(args->hmm, args->iprobs); + + args->summary_fh = stdout; + init_sample_files(&args->query_sample, args->output_dir); + if ( args->control_sample.name ) + { + init_sample_files(&args->control_sample, args->output_dir); + args->summary_fh = open_file(&args->summary_fname,"w","%s/summary.tab",args->output_dir); + } + else + args->summary_fh = NULL; // one sample only, no two-file summary + + + int i; + FILE *fh = args->summary_fh ? args->summary_fh : args->query_sample.summary_fh; + + fprintf(fh, "# This file was produced by: bcftools cnv(%s+htslib-%s)\n", bcftools_version(),hts_version()); + fprintf(fh, "# The command line was:\tbcftools %s", args->argv[0]); + for (i=1; iargc; i++) fprintf(fh, " %s",args->argv[i]); + if ( args->control_sample.name ) + fprintf(fh, "\n#\n" + "# RG, Regions\t[2]Chromosome\t[3]Start\t[4]End\t[5]Copy number:%s\t[6]Copy number:%s\t[7]Quality" + "\t[8]nSites in (5)\t[9]nHETs in (5)\t[10]nSites in (6)\t[11]nHETs in(6)\n", + args->query_sample.name,args->control_sample.name + ); + else + fprintf(fh, "\n#\n" + "# RG, Regions\t[2]Chromosome\t[3]Start\t[4]End\t[5]Copy number:%s\t[6]Quality\t[7]nSites\t[8]nHETs\n", + args->query_sample.name + ); + if ( args->optimize_frac ) + { + fprintf(args->query_sample.summary_fh, "# CF, cell fraction estimate\t[2]Chromosome\t[3]Start\t[4]End\t[5]Cell fraction\t[6]BAF deviation\n"); + if ( args->control_sample.name ) + { + fprintf(args->control_sample.summary_fh, "# CF, cell fraction estimate\t[2]Chromosome\t[3]Start\t[4]End\t[5]Cell fraction\t[6]BAF deviation\n"); + fprintf(args->summary_fh, "# CF, cell fraction estimate\t[2]Chromosome\t[3]Start\t[4]End\t" + "[5]Cell fraction:%s\t[6]Cell fraction:%s\t[7]BAF deviation:%s\t[8]BAF deviation:%s\n", + args->query_sample.name,args->control_sample.name, + args->query_sample.name,args->control_sample.name + ); + } + } +} + +char *msprintf(const char *fmt, ...); +static void py_plot_cnv(char *script, float th) +{ + if ( th>100 ) return; // create no plots + + char *cmd = msprintf("python %s -p %f", script, th); + int ret = system(cmd); + if ( ret) fprintf(stderr, "The command returned non-zero status %d: %s\n", ret, cmd); + free(cmd); +} + +static void plot_sample(args_t *args, sample_t *smpl) +{ + char *fname; + FILE *fp = open_file(&fname,"w","%s/plot.%s.py",args->output_dir,smpl->name); + fprintf(fp, + "import matplotlib as mpl\n" + "mpl.use('Agg')\n" + "import matplotlib.pyplot as plt\n" + "import csv\n" + "import numpy as np\n" + "csv.register_dialect('tab', delimiter='\\t', quoting=csv.QUOTE_NONE)\n" + "\n" + "dat = {}\n" + "with open('%s', 'rb') as f:\n" + " reader = csv.reader(f, 'tab')\n" + " for row in reader:\n" + " chr = row[0]\n" + " if chr[0]=='#': continue\n" + " if chr not in dat: dat[chr] = []\n" + " dat[chr].append([row[1], float(row[2]), float(row[3])])\n" + "\n" + "cnv = {}\n" + "with open('%s', 'rb') as f:\n" + " reader = csv.reader(f, 'tab')\n" + " for row in reader:\n" + " chr = row[0]\n" + " if chr[0]=='#': continue\n" + " if chr not in cnv: cnv[chr] = []\n" + " row[2] = int(row[2]) + 0.5\n" + " cnv[chr].append(row[1:])\n" + "\n" + "for chr in dat:\n" + " fig,(ax1, ax2, ax3) = plt.subplots(3,1,figsize=(10,8),sharex=True)\n" + " ax1.plot([x[0] for x in dat[chr]],[x[2] for x in dat[chr]], '.', ms=3)\n" + " ax2.plot([x[0] for x in dat[chr]],[x[1] for x in dat[chr]], '.', ms=3)\n" + " cn_dat = cnv[chr]\n" + " xgrid = [float(x[0]) for x in cn_dat]\n" + " ygrid = np.linspace(0,5,6)\n" + " xgrid, ygrid = np.meshgrid(xgrid, ygrid)\n" + " heat = np.zeros_like(xgrid)\n" + " for x in range(len(heat[0])-1):\n" + " heat[0][x] = cn_dat[x][2]\n" + " heat[1][x] = cn_dat[x][3]\n" + " heat[2][x] = cn_dat[x][4]\n" + " heat[3][x] = cn_dat[x][5]\n" + " mesh = ax3.pcolormesh(xgrid, ygrid, heat, cmap='bwr_r')\n" + " mesh.set_clim(vmin=-1,vmax=1)\n" + " ax3.plot([x[0] for x in cn_dat],[x[1] for x in cn_dat],'.-',ms=3,color='black')\n" + " fig.suptitle('%s (chr '+chr+')')\n" + " ax1.set_title('Log-R intensities Ratio',fontsize=10)\n" + " ax2.set_title('B-Allele Frequency',fontsize=10)\n" + " ax3.set_title('Copy Number Variation',fontsize=10)\n" + " ax1.set_ylabel('LRR')\n" + " ax2.set_ylabel('BAF')\n" + " ax3.set_ylabel('CN')\n" + " ax3.set_xlabel('Coordinate (chrom '+chr+')',fontsize=10)\n" + " ax3.set_ylim(-0.1,4.1)\n" + " ax3.set_yticks([0.5,1.5,2.5,3.5])\n" + " ax3.set_yticklabels(['CN0','CN1','CN2','CN3'])\n" + " plt.subplots_adjust(left=0.08,right=0.95,bottom=0.08,top=0.92)\n" + " plt.savefig('%s/plot.%s.chr'+chr+'.png')\n" + " plt.close()\n" + "\n", + smpl->dat_fname,smpl->cn_fname,smpl->name,args->output_dir,smpl->name + ); + fclose(fp); + + py_plot_cnv(fname, args->plot_th); + free(fname); +} + +static void create_plots(args_t *args) +{ + close_sample_files(&args->query_sample); + if ( args->control_sample.name ) close_sample_files(&args->control_sample); + if ( args->summary_fh ) fclose(args->summary_fh); + + if ( !args->control_sample.name ) + { + plot_sample(args, &args->query_sample); + return; + } + + char *fname; + FILE *fp = open_file(&fname,"w","%s/plot.%s.%s.py",args->output_dir,args->control_sample.name,args->query_sample.name); + fprintf(fp, + "import matplotlib as mpl\n" + "mpl.use('Agg')\n" + "import matplotlib.pyplot as plt\n" + "import csv,argparse\n" + "import numpy as np\n" + "csv.register_dialect('tab', delimiter='\\t', quoting=csv.QUOTE_NONE)\n" + "\n" + "control_sample = '%s'\n" + "query_sample = '%s'\n" + "\n" + "parser = argparse.ArgumentParser()\n" + "parser.add_argument('-p', '--plot-threshold', type=float)\n" + "parser.add_argument('-c', '--chromosome')\n" + "args = parser.parse_args()\n" + "if args.plot_threshold==None: args.plot_threshold = 0\n" + "\n" + "def chroms_to_plot(th):\n" + " dat = {}\n" + " with open('%s/summary.tab', 'rb') as f:\n" + " reader = csv.reader(f, 'tab')\n" + " for row in reader:\n" + " if row[0]!='RG': continue\n" + " chr = row[1]\n" + " start = row[2]\n" + " end = row[3]\n" + " qual = float(row[6])\n" + " if row[4]==row[5] and args.plot_threshold!=0: continue\n" + " if chr not in dat: dat[chr] = 0.0\n" + " if qual > dat[chr]: dat[chr] = qual\n" + " out = {}\n" + " for chr in dat:\n" + " if (chr not in dat) or dat[chr]0: diff.append([b[i-1][0],b[i-1][1],a[i-1][1]])\n" + " diff.append([b[i][0],b[i][1],a[i][1]])\n" + " elif len(diff):\n" + " diff.append([b[i][0],b[i][1],a[i][1]])\n" + " out.append(diff)\n" + " diff = []\n" + " if len(diff): out.append(diff)\n" + " return out\n" + "\n" + "for chr in sorted(plot_chroms.keys()):\n" + " control_dat = []\n" + " control_cnv = []\n" + " query_dat = []\n" + " query_cnv = []\n" + " read_dat('%s',control_dat,chr)\n" + " read_dat('%s',query_dat,chr)\n" + " read_cnv('%s',control_cnv,chr)\n" + " read_cnv('%s',query_cnv,chr)\n" + "\n" + " fig,(ax1,ax2,ax3,ax4,ax5,ax6) = plt.subplots(6,1,figsize=(10,8),sharex=True)\n" + " ax1.plot([x[0] for x in control_dat],[x[2] for x in control_dat], '.', ms=3,color='red')\n" + " ax2.plot([x[0] for x in control_dat],[x[1] for x in control_dat], '.', ms=3,color='red')\n" + " cn_dat = control_cnv\n" + " xgrid = [float(x[0]) for x in cn_dat]\n" + " ygrid = np.linspace(0,5,6)\n" + " xgrid, ygrid = np.meshgrid(xgrid, ygrid)\n" + " heat = np.zeros_like(xgrid)\n" + " for x in range(len(heat[0])-1):\n" + " heat[0][x] = cn_dat[x][2]\n" + " heat[1][x] = cn_dat[x][3]\n" + " heat[2][x] = cn_dat[x][4]\n" + " heat[3][x] = cn_dat[x][5]\n" + " mesh = ax3.pcolormesh(xgrid, ygrid, heat, cmap='bwr')\n" + " mesh.set_clim(vmin=-1,vmax=1)\n" + " ax3.plot([x[0] for x in cn_dat],[x[1] for x in cn_dat],'-',ms=3,color='black',lw=1.7)\n" + "\n" + " ax6.plot([x[0] for x in query_dat],[x[2] for x in query_dat], '.', ms=3)\n" + " ax5.plot([x[0] for x in query_dat],[x[1] for x in query_dat], '.', ms=3)\n" + " cn_dat = query_cnv\n" + " xgrid = [float(x[0]) for x in cn_dat]\n" + " ygrid = np.linspace(0,5,6)\n" + " xgrid, ygrid = np.meshgrid(xgrid, ygrid)\n" + " heat = np.zeros_like(xgrid)\n" + " for x in range(len(heat[0])-1):\n" + " heat[0][x] = cn_dat[x][2]\n" + " heat[1][x] = cn_dat[x][3]\n" + " heat[2][x] = cn_dat[x][4]\n" + " heat[3][x] = cn_dat[x][5]\n" + " mesh = ax4.pcolormesh(xgrid, ygrid, heat, cmap='bwr_r')\n" + " mesh.set_clim(vmin=-1,vmax=1)\n" + " ax4.plot([x[0] for x in cn_dat],[x[1] for x in cn_dat],'-',ms=3,color='black',lw=1.7)\n" + " ax3.annotate(control_sample, xy=(0.02,0.1), xycoords='axes fraction', color='red',fontsize=12, va='bottom',ha='left')\n" + " ax4.annotate(query_sample, xy=(0.02,0.9), xycoords='axes fraction', color='blue',fontsize=12, va='top',ha='left')\n" + "\n" + " diffs = find_diffs(control_cnv,query_cnv)\n" + " for diff in diffs:\n" + " ax3.plot([x[0] for x in diff],[x[1] for x in diff],'-',ms=3,color='blue',lw=1.7)\n" + " ax4.plot([x[0] for x in diff],[x[2] for x in diff],'-',ms=3,color='red',lw=1.7)\n" + "\n" + " fig.suptitle('chr '+chr+', '+control_sample+' vs '+query_sample)\n" + " ax1.tick_params(axis='both', labelsize=8)\n" + " ax2.tick_params(axis='both', labelsize=8)\n" + " ax3.tick_params(axis='both', labelsize=8)\n" + " ax4.tick_params(axis='both', labelsize=8)\n" + " ax5.tick_params(axis='both', labelsize=8)\n" + " ax6.tick_params(axis='both', labelsize=8)\n" + " ax6.set_xlabel('Coordinate (chrom '+chr+')',fontsize=8)\n" + " ax1.set_ylabel('LRR')\n" + " ax2.set_ylabel('BAF')\n" + " ax3.set_ylabel('CN')\n" + " ax6.set_ylabel('LRR')\n" + " ax5.set_ylabel('BAF')\n" + " ax4.set_ylabel('CN')\n" + " ax3.set_ylim(-0.1,4.1)\n" + " ax3.set_yticks([0.5,1.5,2.5,3.5])\n" + " ax3.set_yticklabels(['CN0','CN1','CN2','CN3'])\n" + " ax4.set_ylim(-0.1,4.1)\n" + " ax4.set_yticks([0.5,1.5,2.5,3.5])\n" + " ax4.set_yticklabels(['CN0','CN1','CN2','CN3'])\n" + " plt.subplots_adjust(left=0.08,right=0.95,bottom=0.08,top=0.92,hspace=0)\n" + " plt.savefig('%s/plot.%s.%s.chr'+chr+'.png')\n" + " plt.close()\n" + "\n", + args->control_sample.name,args->query_sample.name, + args->output_dir, + args->control_sample.dat_fname,args->query_sample.dat_fname, + args->control_sample.cn_fname,args->query_sample.cn_fname, + args->output_dir,args->control_sample.name,args->query_sample.name + ); + fclose(fp); + + py_plot_cnv(fname,args->plot_th); + free(fname); +} + +static void destroy_data(args_t *args) +{ + bcf_sr_destroy(args->files); + hmm_destroy(args->hmm); + free(args->tmpf); + free(args->sites); + free(args->eprob); + free(args->tprob); + free(args->iprobs); + free(args->summary_fname); + free(args->nonref_afs); + free(args->query_sample.baf); + free(args->query_sample.lrr); + free(args->control_sample.baf); + free(args->control_sample.lrr); + free(args->query_sample.name); + free(args->query_sample.dat_fname); + free(args->query_sample.cn_fname); + free(args->query_sample.summary_fname); + free(args->control_sample.dat_fname); + free(args->control_sample.cn_fname); + free(args->control_sample.summary_fname); +} + +static inline char copy_number_state(args_t *args, int istate, int ismpl) +{ + char code[] = "01234"; + if ( !args->control_sample.name ) return code[istate]; + int idx = ismpl ? istate - (istate/N_STATES)*N_STATES : istate/N_STATES; + return code[idx]; +} + +static double avg_ii_prob(int n, double *mat) +{ + int i; + double avg = 0; + for (i=0; igauss_param[0])) +#define GAUSS_CN1_PK_A(smpl) (&((smpl)->gauss_param[1])) +#define GAUSS_CN2_PK_RR(smpl) (&((smpl)->gauss_param[2])) +#define GAUSS_CN2_PK_RA(smpl) (&((smpl)->gauss_param[3])) +#define GAUSS_CN2_PK_AA(smpl) (&((smpl)->gauss_param[4])) +#define GAUSS_CN3_PK_RRR(smpl) (&((smpl)->gauss_param[5])) +#define GAUSS_CN3_PK_RRA(smpl) (&((smpl)->gauss_param[6])) +#define GAUSS_CN3_PK_RAA(smpl) (&((smpl)->gauss_param[7])) +#define GAUSS_CN3_PK_AAA(smpl) (&((smpl)->gauss_param[8])) + +static inline double norm_prob(double baf, gauss_param_t *param) +{ + return exp(-(baf-param->mean)*(baf-param->mean)*0.5/param->dev2) / param->norm / sqrt(2*M_PI*param->dev2); +} + +static int set_observed_prob(args_t *args, sample_t *smpl, int isite) +{ + float baf = smpl->baf[isite]; + float lrr = args->lrr_bias>0 ? smpl->lrr[isite] : 0; + + float fRR = args->fRR; + float fRA = args->fRA; + float fAA = args->fAA; + + if ( baf<0 ) + { + // no call: either some technical issue or the call could not be made because it is CN0 + int i; + smpl->pobs[CN0] = 0.5; + for (i=1; ipobs[i] = (1.0-smpl->pobs[CN0])/(N_STATES-1); + return 0; + } + + double cn1_baf = + norm_prob(baf,GAUSS_CN1_PK_R(smpl)) * (fRR + fRA*0.5) + + norm_prob(baf,GAUSS_CN1_PK_A(smpl)) * (fAA + fRA*0.5) ; + double cn2_baf = + norm_prob(baf,GAUSS_CN2_PK_RR(smpl)) * fRR + + norm_prob(baf,GAUSS_CN2_PK_RA(smpl)) * fRA + + norm_prob(baf,GAUSS_CN2_PK_AA(smpl)) * fAA; + double cn3_baf = + norm_prob(baf,GAUSS_CN3_PK_RRR(smpl)) * fRR + + norm_prob(baf,GAUSS_CN3_PK_RRA(smpl)) * fRA*0.5 + + norm_prob(baf,GAUSS_CN3_PK_RAA(smpl)) * fRA*0.5 + + norm_prob(baf,GAUSS_CN3_PK_AAA(smpl)) * fAA; + + double norm = cn1_baf + cn2_baf + cn3_baf; + cn1_baf /= norm; + cn2_baf /= norm; + cn3_baf /= norm; + + #if DBG0 + if ( args->verbose ) fprintf(stderr,"%f\t%f %f %f\n", baf,cn1_baf,cn2_baf,cn3_baf); + #endif + + double cn1_lrr = exp(-(lrr + 0.45)*(lrr + 0.45)/smpl->lrr_dev2); + double cn2_lrr = exp(-(lrr - 0.00)*(lrr - 0.00)/smpl->lrr_dev2); + double cn3_lrr = exp(-(lrr - 0.30)*(lrr - 0.30)/smpl->lrr_dev2); + + smpl->pobs[CN0] = 0; + smpl->pobs[CN1] = args->err_prob + (1 - args->baf_bias + args->baf_bias*cn1_baf)*(1 - args->lrr_bias + args->lrr_bias*cn1_lrr); + smpl->pobs[CN2] = args->err_prob + (1 - args->baf_bias + args->baf_bias*cn2_baf)*(1 - args->lrr_bias + args->lrr_bias*cn2_lrr); + smpl->pobs[CN3] = args->err_prob + (1 - args->baf_bias + args->baf_bias*cn3_baf)*(1 - args->lrr_bias + args->lrr_bias*cn3_lrr); + + return 0; +} + +static void set_emission_prob(args_t *args, int isite) +{ + double *eprob = &args->eprob[args->nstates*isite]; + int i; + for (i=0; iquery_sample.pobs[i]; +} + +static void set_emission_prob2(args_t *args, int isite) +{ + double *eprob = &args->eprob[args->nstates*isite]; + int i, j; + for (i=0; iquery_sample.pobs[i]*args->control_sample.pobs[j]; + } + } +} + +static void set_gauss_params(args_t *args, sample_t *smpl); +static double norm_cdf(double mean, double dev) +{ + double bot = 0, top = 1; + top = 1 - 0.5*erfc((top-mean)/(dev*sqrt(2))); + bot = 1 - 0.5*erfc((bot-mean)/(dev*sqrt(2))); + return top-bot; +} + +static void set_emission_probs(args_t *args) +{ + if ( !args->af_fname ) + { + args->fRR = 0.76; + args->fRA = 0.14; + args->fAA = 0.098; + } + + set_gauss_params(args, &args->query_sample); + if ( args->control_sample.name ) set_gauss_params(args, &args->control_sample); + + #if DBG0 + args->verbose = 1; + args->query_sample.baf[0] = 0; set_observed_prob(args,&args->query_sample,0); + args->query_sample.baf[0] = 1/3.; set_observed_prob(args,&args->query_sample,0); + args->query_sample.baf[0] = 1/2.; set_observed_prob(args,&args->query_sample,0); + args->query_sample.baf[0] = 2/3.; set_observed_prob(args,&args->query_sample,0); + args->query_sample.baf[0] = 1; set_observed_prob(args,&args->query_sample,0); + args->verbose = 0; + #endif + + int i; + for (i=0; insites; i++) + { + if ( args->af_fname ) + { + args->fRR = (1-args->nonref_afs[i])*(1-args->nonref_afs[i]); + args->fRA = 2*args->nonref_afs[i]*(1-args->nonref_afs[i]); + args->fAA = args->nonref_afs[i]*args->nonref_afs[i]; + } + set_observed_prob(args,&args->query_sample,i); + if ( args->control_sample.name ) + { + set_observed_prob(args,&args->control_sample,i); + set_emission_prob2(args,i); + } + else + set_emission_prob(args,i); + } +} + +static void smooth_data(float *dat, int ndat, int win) +{ + if ( win<=1 ) return; + + int i,j, k1 = win/2, k2 = win-k1; + rbuf_t rbuf; + rbuf_init(&rbuf,win); + float sum = 0, *buf = (float*)malloc(sizeof(float)*win); + for (i=0; i=k1 ) + { + j = rbuf_shift(&rbuf); + sum -= buf[j]; + } + if ( i+k2gauss_param[i].dev2 = smpl->baf_dev2; + + double dev = sqrt(smpl->baf_dev2); + + GAUSS_CN1_PK_R(smpl)->mean = 0; + GAUSS_CN1_PK_A(smpl)->mean = 1; + GAUSS_CN1_PK_R(smpl)->norm = norm_cdf(GAUSS_CN1_PK_R(smpl)->mean,dev); + GAUSS_CN1_PK_A(smpl)->norm = norm_cdf(GAUSS_CN1_PK_A(smpl)->mean,dev); + + GAUSS_CN2_PK_RR(smpl)->mean = 0; + GAUSS_CN2_PK_RA(smpl)->mean = 0.5; + GAUSS_CN2_PK_AA(smpl)->mean = 1; + GAUSS_CN2_PK_RR(smpl)->norm = norm_cdf(GAUSS_CN2_PK_RR(smpl)->mean,dev); + GAUSS_CN2_PK_RA(smpl)->norm = norm_cdf(GAUSS_CN2_PK_RA(smpl)->mean,dev); + GAUSS_CN2_PK_AA(smpl)->norm = norm_cdf(GAUSS_CN2_PK_AA(smpl)->mean,dev); + + GAUSS_CN3_PK_RRR(smpl)->mean = 0; + GAUSS_CN3_PK_RRA(smpl)->mean = 1.0/(2+smpl->cell_frac); + GAUSS_CN3_PK_RAA(smpl)->mean = (1.0+smpl->cell_frac)/(2+smpl->cell_frac); + GAUSS_CN3_PK_AAA(smpl)->mean = 1; + GAUSS_CN3_PK_RRR(smpl)->norm = norm_cdf(GAUSS_CN3_PK_RRR(smpl)->mean,dev); + GAUSS_CN3_PK_RRA(smpl)->norm = norm_cdf(GAUSS_CN3_PK_RRA(smpl)->mean,dev); + GAUSS_CN3_PK_RAA(smpl)->norm = norm_cdf(GAUSS_CN3_PK_RAA(smpl)->mean,dev); + GAUSS_CN3_PK_AAA(smpl)->norm = norm_cdf(GAUSS_CN3_PK_AAA(smpl)->mean,dev); +} + +static int update_sample_args(args_t *args, sample_t *smpl, int ismpl) +{ + hmm_t *hmm = args->hmm; + double *fwd = hmm_get_fwd_bwd_prob(hmm); + int nstates = hmm_get_nstates(hmm); + + // estimate the BAF mean and deviation for CN3 + double mean_cn3 = 0, norm_cn3 = 0; + double baf_dev2 = 0, baf_AA_dev2 = 0, norm_baf_AA_dev2 = 0; + + // experimental: smooth CN3 probs to bias toward bigger events, this lowers + // the FP rate when the data is noisy + hts_expand(float,args->nsites,args->mtmpf,args->tmpf); + int i, j, k = 0; + for (i=0; insites; i++) + { + float baf = smpl->baf[i]; + if ( baf>4/5.) continue; // skip AA genotypes + if ( baf>0.5 ) baf = 1 - baf; // the bands should be symmetric + if ( baf<1/5.) continue; // skip RR genotypes + + double prob_cn3 = 0, *probs = fwd + i*nstates; + if ( !args->control_sample.name ) + { + prob_cn3 = probs[CN3]; + } + else if ( ismpl==0 ) + { + // query sample: CN3 probability must be recovered from all states of the control sample + for (j=0; jtmpf[k++] = prob_cn3; + } + smooth_data(args->tmpf, k, 50); + k = 0; + for (i=0; insites; i++) + { + float baf = smpl->baf[i]; + if ( baf>4/5.) { baf_AA_dev2 += (1.0-baf)*(1.0-baf); norm_baf_AA_dev2++; continue; } // skip AA genotypes + if ( baf>0.5 ) baf = 1 - baf; // the bands should be symmetric + if ( baf<1/5.) continue; // skip RR genotypes + + double prob_cn3 = args->tmpf[k++]; + mean_cn3 += prob_cn3 * baf; + norm_cn3 += prob_cn3; + } + if ( !norm_cn3 ) + { + smpl->cell_frac = 1.0; + return 1; + } + mean_cn3 /= norm_cn3; + k = 0; + for (i=0; insites; i++) + { + float baf = smpl->baf[i]; + if ( baf>0.5 ) baf = 1 - baf; // the bands should be symmetric + if ( baf<1/5.) continue; // skip RR,AA genotypes + + double prob_cn3 = args->tmpf[k++]; + baf_dev2 += prob_cn3 * (baf - mean_cn3)*(baf - mean_cn3); + } + + /* + A noisy CN2 band is hard to distinguish from two CN3 bands which are + close to each other. Set a treshold on the minimum separation based + on the BAF deviation at p=0.95 + */ + baf_dev2 /= norm_cn3; + baf_AA_dev2 /= norm_baf_AA_dev2; + if ( baf_dev2 < baf_AA_dev2 ) baf_dev2 = baf_AA_dev2; + double max_mean_cn3 = 0.5 - sqrt(baf_dev2)*1.644854; // R: qnorm(0.95)=1.644854 + //fprintf(stderr,"dev=%f AA_dev=%f max_mean_cn3=%f mean_cn3=%f\n", baf_dev2,baf_AA_dev2,max_mean_cn3,mean_cn3); + assert( max_mean_cn3>0 ); + + double new_frac = 1./mean_cn3 - 2; + if ( mean_cn3 > max_mean_cn3 || new_frac < args->optimize_frac ) + { + // out of bounds, beyond our detection limits. Give up and say it converged + smpl->cell_frac = 1.0; + return 1; + } + if ( new_frac>1 ) new_frac = 1; + int converged = fabs(new_frac - smpl->cell_frac) < 1e-1 ? 1 : 0; + + // Update dev2, but stay within safe limits + if ( baf_dev2 > 3*smpl->baf_dev2_dflt ) baf_dev2 = 3*smpl->baf_dev2_dflt; + else if ( baf_dev2 < 0.5*smpl->baf_dev2_dflt ) baf_dev2 = 0.5*smpl->baf_dev2_dflt; + + smpl->cell_frac = new_frac; + smpl->baf_dev2 = baf_dev2; + + return converged; +} + +// Update parameters which depend on the estimated fraction of aberrant cells +// in CN3. Returns 0 if the current estimate did not need to be updated or 1 +// if there was a change. +static int update_args(args_t *args) +{ + int converged = update_sample_args(args, &args->query_sample, 0); + if ( args->control_sample.name ) + { + converged += update_sample_args(args, &args->control_sample, 1); + return converged==2 ? 0 : 1; + } + return converged ? 0 : 1; +} + +// for an approximate estimate of the number of het genotypes in a region +#define BAF_LIKELY_HET(val) (val)>0.25 && (val)<0.75 + +static void cnv_flush_viterbi(args_t *args) +{ + if ( !args->nsites ) return; + + // Set HMM transition matrix for the new chromsome again. This is for case + // Baum-Welch was used, which is experimental, largerly unsupported and not + // done by default. + hmm_t *hmm = args->hmm; + hmm_set_tprob(args->hmm, args->tprob, 10000); + + // Smooth LRR values to reduce noise + if ( args->lrr_bias > 0 ) + { + smooth_data(args->query_sample.lrr,args->nsites, args->lrr_smooth_win); + if ( args->control_sample.name ) smooth_data(args->control_sample.lrr,args->nsites, args->lrr_smooth_win); + } + + // Set the BAF peak likelihoods, such as P(RRR|CN3), taking account the + // estimated fraction of aberrant cells in the mixture. With the new chromosome, + // reset the fraction to the default value. + args->query_sample.cell_frac = args->query_sample.cell_frac_dflt; + args->control_sample.cell_frac = args->control_sample.cell_frac_dflt; + args->query_sample.baf_dev2 = args->query_sample.baf_dev2_dflt; + args->control_sample.baf_dev2 = args->control_sample.baf_dev2_dflt; + set_gauss_params(args, &args->query_sample); + if ( args->control_sample.name ) set_gauss_params(args, &args->control_sample); + + if ( args->optimize_frac ) + { + int niter = 0; + fprintf(stderr,"Attempting to estimate the fraction of aberrant cells (chr %s):\n", bcf_hdr_id2name(args->hdr,args->prev_rid)); + do + { + fprintf(stderr,"\t.. %f %f", args->query_sample.cell_frac,args->query_sample.baf_dev2); + if ( args->control_sample.name ) + fprintf(stderr,"\t.. %f %f", args->control_sample.cell_frac,args->control_sample.baf_dev2); + fprintf(stderr,"\n"); + set_emission_probs(args); + hmm_run_fwd_bwd(hmm, args->nsites, args->eprob, args->sites); + } + while ( update_args(args) && ++niter<20 ); + if ( niter>=20 ) + { + // no convergence + args->query_sample.cell_frac = args->query_sample.cell_frac_dflt; + args->control_sample.cell_frac = args->control_sample.cell_frac_dflt; + args->query_sample.baf_dev2 = args->query_sample.baf_dev2_dflt; + args->control_sample.baf_dev2 = args->control_sample.baf_dev2_dflt; + set_gauss_params(args, &args->query_sample); + if ( args->control_sample.name ) set_gauss_params(args, &args->control_sample); + } + + fprintf(stderr,"\t.. %f %f", args->query_sample.cell_frac,args->query_sample.baf_dev2); + if ( args->control_sample.name ) + fprintf(stderr,"\t.. %f %f", args->control_sample.cell_frac,args->control_sample.baf_dev2); + fprintf(stderr,"\n"); + + fprintf(args->query_sample.summary_fh,"CF\t%s\t%d\t%d\t%.2f\t%f\n", + bcf_hdr_id2name(args->hdr,args->prev_rid),args->sites[0]+1,args->sites[args->nsites-1]+1, + args->query_sample.cell_frac,sqrt(args->query_sample.baf_dev2)); + if ( args->control_sample.name ) + { + fprintf(args->control_sample.summary_fh,"CF\t%s\t%d\t%d\t%.2f\t%f\n", + bcf_hdr_id2name(args->hdr,args->prev_rid),args->sites[0]+1,args->sites[args->nsites-1]+1, + args->control_sample.cell_frac,sqrt(args->control_sample.baf_dev2)); + fprintf(args->summary_fh,"CF\t%s\t%d\t%d\t%.2f\t%.2f\t%f\t%f\n", + bcf_hdr_id2name(args->hdr,args->prev_rid),args->sites[0]+1,args->sites[args->nsites-1]+1, + args->query_sample.cell_frac, args->control_sample.cell_frac, + sqrt(args->query_sample.baf_dev2), sqrt(args->control_sample.baf_dev2)); + } + } + set_emission_probs(args); + + while ( args->baum_welch_th!=0 ) + { + int nstates = hmm_get_nstates(hmm); + double ori_ii = avg_ii_prob(nstates,hmm_get_tprob(hmm)); + hmm_run_baum_welch(hmm, args->nsites, args->eprob, args->sites); + double new_ii = avg_ii_prob(nstates,hmm_get_tprob(hmm)); + fprintf(stderr,"%e\t%e\t%e\n", ori_ii,new_ii,new_ii-ori_ii); + double *tprob = init_tprob_matrix(nstates, 1-new_ii, args->same_prob); + hmm_set_tprob(args->hmm, tprob, 10000); + double *tprob_arr = hmm_get_tprob(hmm); + free(tprob); + if ( fabs(new_ii - ori_ii) < args->baum_welch_th ) + { + int i,j; + for (i=0; insites, args->eprob, args->sites); + hmm_run_fwd_bwd(hmm, args->nsites, args->eprob, args->sites); + + + // Output the results + uint8_t *vpath = hmm_get_viterbi_path(hmm); + double qual = 0, *fwd = hmm_get_fwd_bwd_prob(hmm); + int i,j, isite, start_cn = vpath[0], start_pos = args->sites[0], istart_pos = 0; + int ctrl_ntot = 0, smpl_ntot = 0, ctrl_nhet = 0, smpl_nhet = 0; + for (isite=0; isitensites; isite++) + { + int state = vpath[args->nstates*isite]; + double *pval = fwd + isite*args->nstates; + + qual += pval[start_cn]; + + // output CN and fwd-bwd likelihood for each site + if ( args->query_sample.cn_fh ) + { + fprintf(args->query_sample.cn_fh, "%s\t%d\t%c", bcf_hdr_id2name(args->hdr,args->prev_rid), args->sites[isite]+1, copy_number_state(args,state,0)); + if ( !args->control_sample.cn_fh ) + for (i=0; instates; i++) fprintf(args->query_sample.cn_fh, "\t%f", pval[i]); + else + for (i=0; iquery_sample.cn_fh, "\t%f", sum); + } + fprintf(args->query_sample.cn_fh, "\n"); + if ( args->query_sample.baf[isite]>=0 ) // if non-missing + { + if ( BAF_LIKELY_HET(args->query_sample.baf[isite]) ) smpl_nhet++; + smpl_ntot++; + } + } + if ( args->control_sample.cn_fh ) + { + fprintf(args->control_sample.cn_fh, "%s\t%d\t%c", bcf_hdr_id2name(args->hdr,args->prev_rid), args->sites[isite]+1, copy_number_state(args,state,1)); + for (i=0; icontrol_sample.cn_fh, "\t%f", sum); + } + fprintf(args->control_sample.cn_fh, "\n"); + if ( args->control_sample.baf[isite]>=0 ) // if non-missing + { + if ( BAF_LIKELY_HET(args->control_sample.baf[isite]) ) ctrl_nhet++; + ctrl_ntot++; + } + } + + if ( start_cn != state ) + { + char start_cn_query = copy_number_state(args,start_cn,0); + qual = phred_score(1 - qual/(isite - istart_pos)); + fprintf(args->query_sample.summary_fh,"RG\t%s\t%d\t%d\t%c\t%.1f\t%d\t%d\n", + bcf_hdr_id2name(args->hdr,args->prev_rid), start_pos+1, args->sites[isite],start_cn_query,qual,smpl_ntot,smpl_nhet); + + if ( args->control_sample.name ) + { + // regions 0-based, half-open + char start_cn_ctrl = copy_number_state(args,start_cn,1); + fprintf(args->control_sample.summary_fh,"RG\t%s\t%d\t%d\t%c\t%.1f\t%d\t%d\n", + bcf_hdr_id2name(args->hdr,args->prev_rid), start_pos+1, args->sites[isite],start_cn_ctrl,qual,ctrl_ntot,ctrl_nhet); + fprintf(args->summary_fh,"RG\t%s\t%d\t%d\t%c\t%c\t%.1f\t%d\t%d\t%d\t%d\n", + bcf_hdr_id2name(args->hdr,args->prev_rid), start_pos+1, args->sites[isite],start_cn_query,start_cn_ctrl,qual,smpl_ntot,smpl_nhet,ctrl_ntot,ctrl_nhet); + } + + istart_pos = isite; + start_pos = args->sites[isite]; + start_cn = state; + qual = 0; + smpl_ntot = smpl_nhet = ctrl_ntot = ctrl_nhet = 0; + } + } + qual = phred_score(1 - qual/(isite - istart_pos)); + char start_cn_query = copy_number_state(args,start_cn,0); + fprintf(args->query_sample.summary_fh,"RG\t%s\t%d\t%d\t%c\t%.1f\t%d\t%d\n", + bcf_hdr_id2name(args->hdr,args->prev_rid), start_pos+1, args->sites[isite-1]+1,start_cn_query,qual,smpl_ntot,smpl_nhet); + if ( args->control_sample.name ) + { + char start_cn_ctrl = copy_number_state(args,start_cn,1); + fprintf(args->control_sample.summary_fh,"RG\t%s\t%d\t%d\t%c\t%.1f\t%d\t%d\n", + bcf_hdr_id2name(args->hdr,args->prev_rid), start_pos+1, args->sites[isite-1]+1,start_cn_ctrl,qual,ctrl_ntot,ctrl_nhet); + fprintf(args->summary_fh,"RG\t%s\t%d\t%d\t%c\t%c\t%.1f\t%d\t%d\t%d\t%d\n", + bcf_hdr_id2name(args->hdr,args->prev_rid), start_pos+1, args->sites[isite-1]+1,start_cn_query,start_cn_ctrl,qual,smpl_ntot,smpl_nhet,ctrl_ntot,ctrl_nhet); + } +} + +static int parse_lrr_baf(sample_t *smpl, bcf_fmt_t *baf_fmt, bcf_fmt_t *lrr_fmt, float *baf, float *lrr) +{ + *baf = ((float*)(baf_fmt->p + baf_fmt->size*smpl->idx))[0]; + if ( bcf_float_is_missing(*baf) || isnan(*baf) ) *baf = -0.1; // arbitrary negative value == missing value + + if ( lrr_fmt ) + { + *lrr = ((float*)(lrr_fmt->p + lrr_fmt->size*smpl->idx))[0]; + if ( bcf_float_is_missing(*lrr) || isnan(*lrr) ) { *lrr = 0; *baf = -0.1; } + } + else + *lrr = 0; + + return *baf<0 ? 0 : 1; +} + +int read_AF(bcf_sr_regions_t *tgt, bcf1_t *line, double *alt_freq); + +static void cnv_next_line(args_t *args, bcf1_t *line) +{ + if ( !line ) + { + // Done, flush viterbi + cnv_flush_viterbi(args); + return; + } + + if ( line->rid!=args->prev_rid ) + { + // New chromosome + cnv_flush_viterbi(args); + args->prev_rid = line->rid; + args->nsites = 0; + args->nRR = args->nAA = args->nRA = 0; + } + + // Process line + args->ntot++; + + bcf_fmt_t *baf_fmt, *lrr_fmt = NULL; + if ( !(baf_fmt = bcf_get_fmt(args->hdr, line, "BAF")) ) return; + if ( args->lrr_bias>0 && !(lrr_fmt = bcf_get_fmt(args->hdr, line, "LRR")) ) return; + + float baf1,lrr1,baf2,lrr2; + int ret = 0; + ret += parse_lrr_baf(&args->query_sample, baf_fmt,lrr_fmt,&baf1,&lrr1); + ret += parse_lrr_baf(&args->control_sample,baf_fmt,lrr_fmt,&baf2,&lrr2); + if ( !ret ) return; + + // Realloc buffers needed to store observed data and used by viterbi and fwd-bwd + args->nsites++; + int m = args->msites; + hts_expand(uint32_t,args->nsites,args->msites,args->sites); + if ( args->msites!=m ) + { + args->eprob = (double*) realloc(args->eprob,sizeof(double)*args->msites*args->nstates); + if ( args->control_sample.name ) + { + args->control_sample.lrr = (float*) realloc(args->control_sample.lrr,sizeof(float)*args->msites); + args->control_sample.baf = (float*) realloc(args->control_sample.baf,sizeof(float)*args->msites); + } + args->query_sample.lrr = (float*) realloc(args->query_sample.lrr,sizeof(float)*args->msites); + args->query_sample.baf = (float*) realloc(args->query_sample.baf,sizeof(float)*args->msites); + if ( args->af_fname ) + args->nonref_afs = (float*) realloc(args->nonref_afs,sizeof(float)*args->msites); + } + args->sites[args->nsites-1] = line->pos; + args->query_sample.lrr[args->nsites-1] = lrr1; + args->query_sample.baf[args->nsites-1] = baf1; + if ( args->af_fname ) + { + double alt_freq; + args->nonref_afs[args->nsites-1] = read_AF(args->files->targets,line,&alt_freq)<0 ? args->nonref_af_dflt : alt_freq; + } + if ( args->control_sample.name ) + { + args->control_sample.lrr[args->nsites-1] = lrr2; + args->control_sample.baf[args->nsites-1] = baf2; + if ( baf2>=0 ) // skip missing values + fprintf(args->control_sample.dat_fh,"%s\t%d\t%.3f\t%.3f\n",bcf_hdr_id2name(args->hdr,args->prev_rid), line->pos+1,baf2,lrr2); + } + if ( baf1>=0 ) // skip missing values + fprintf(args->query_sample.dat_fh,"%s\t%d\t%.3f\t%.3f\n",bcf_hdr_id2name(args->hdr,args->prev_rid), line->pos+1,baf1,lrr1); + + if ( baf1>=0 ) + { + if ( baf1<1/5. ) args->nRR++; + else if ( baf1>4/5. ) args->nAA++; + else args->nRA++; + } + args->nused++; +} + +static void usage(args_t *args) +{ + fprintf(stderr, "\n"); + fprintf(stderr, "About: Copy number variation caller, requires Illumina's B-allele frequency (BAF) and Log R\n"); + fprintf(stderr, " Ratio intensity (LRR). The HMM considers the following copy number states: CN 2\n"); + fprintf(stderr, " (normal), 1 (single-copy loss), 0 (complete loss), 3 (single-copy gain)\n"); + fprintf(stderr, "Usage: bcftools cnv [OPTIONS] \n"); + fprintf(stderr, "General Options:\n"); + fprintf(stderr, " -c, --control-sample optional control sample name to highlight differences\n"); + fprintf(stderr, " -f, --AF-file read allele frequencies from file (CHR\\tPOS\\tREF,ALT\\tAF)\n"); + fprintf(stderr, " -o, --output-dir \n"); + fprintf(stderr, " -p, --plot-threshold plot aberrant chromosomes with quality at least 'float'\n"); + fprintf(stderr, " -r, --regions restrict to comma-separated list of regions\n"); + fprintf(stderr, " -R, --regions-file restrict to regions listed in a file\n"); + fprintf(stderr, " -s, --query-sample query samply name\n"); + fprintf(stderr, " -t, --targets similar to -r but streams rather than index-jumps\n"); + fprintf(stderr, " -T, --targets-file similar to -R but streams rather than index-jumps\n"); + fprintf(stderr, "HMM Options:\n"); + fprintf(stderr, " -a, --aberrant fraction of aberrant cells in query and control [1.0,1.0]\n"); + fprintf(stderr, " -b, --BAF-weight relative contribution from BAF [1]\n"); + fprintf(stderr, " -d, --BAF-dev expected BAF deviation in query and control [0.04,0.04]\n"); // experimental + fprintf(stderr, " -e, --err-prob uniform error probability [1e-4]\n"); + fprintf(stderr, " -k, --LRR-dev expected LRR deviation [0.2,0.2]\n"); // experimental + fprintf(stderr, " -l, --LRR-weight relative contribution from LRR [0.2]\n"); + fprintf(stderr, " -L, --LRR-smooth-win window of LRR moving average smoothing [10]\n"); + fprintf(stderr, " -O, --optimize estimate fraction of aberrant cells down to [1.0]\n"); + fprintf(stderr, " -P, --same-prob prior probability of -s/-c being the same [0.5]\n"); + fprintf(stderr, " -x, --xy-prob P(x|y) transition probability [1e-9]\n"); + fprintf(stderr, "\n"); + exit(1); +} + +int main_vcfcnv(int argc, char *argv[]) +{ + int c; + args_t *args = (args_t*) calloc(1,sizeof(args_t)); + args->argc = argc; args->argv = argv; + args->files = bcf_sr_init(); + args->plot_th = 1e9; // by default plot none + args->nonref_af_dflt = 0.1; + args->lrr_smooth_win = 10; + + args->query_sample.cell_frac_dflt = 1; + args->control_sample.cell_frac_dflt = 1; + + // How much FORMAT/LRR and FORMAT/BAF matter + args->lrr_bias = 0.2; + args->baf_bias = 1.0; + args->err_prob = 1e-4; + + // Transition probability to a different state and the prior of both samples being the same + args->ij_prob = 1e-9; + args->same_prob = 0.5; + + // Squared std dev of BAF and LRR values (gaussian noise), estimated from real data (hets, one sample, one chr) + args->query_sample.baf_dev2_dflt = args->control_sample.baf_dev2_dflt = 0.04*0.04; // illumina: 0.03 + args->query_sample.lrr_dev2 = args->control_sample.lrr_dev2 = 0.2*0.2; //0.20*0.20; // illumina: 0.18 + + int regions_is_file = 0, targets_is_file = 0; + static struct option loptions[] = + { + {"BAF-dev",1,0,'d'}, + {"LRR-dev",1,0,'k'}, + {"LRR-smooth-win",1,0,'L'}, + {"AF-file",1,0,'f'}, + {"baum-welch",1,0,'W'}, // hidden + {"optimize",1,0,'O'}, + {"aberrant",1,0,'a'}, + {"err-prob",1,0,'e'}, + {"BAF-weight",1,0,'b'}, + {"LRR-weight",1,0,'l'}, + {"same-prob",1,0,'P'}, + {"xy-prob",1,0,'x'}, + {"sample",1,0,'s'}, + {"control",1,0,'c'}, + {"targets",1,0,'t'}, + {"targets-file",1,0,'T'}, + {"regions",1,0,'r'}, + {"regions-file",1,0,'R'}, + {"plot",1,0,'p'}, + {"output-dir",1,0,'o'}, + {0,0,0,0} + }; + char *tmp = NULL; + while ((c = getopt_long(argc, argv, "h?r:R:t:T:s:o:p:l:T:c:b:P:x:e:O:W:f:a:L:d:k:",loptions,NULL)) >= 0) { + switch (c) { + case 'L': + args->lrr_smooth_win = strtol(optarg,&tmp,10); + if ( *tmp ) error("Could not parse: --LRR-smooth-win %s\n", optarg); + break; + case 'f': args->af_fname = optarg; break; + case 'O': + args->optimize_frac = strtod(optarg,&tmp); + if ( *tmp ) error("Could not parse: -O %s\n", optarg); + break; + case 'd': + args->query_sample.baf_dev2_dflt = strtod(optarg,&tmp); + if ( *tmp ) + { + if ( *tmp!=',') error("Could not parse: -d %s\n", optarg); + args->control_sample.baf_dev2_dflt = strtod(tmp+1,&tmp); + if ( *tmp ) error("Could not parse: -d %s\n", optarg); + } + else + args->control_sample.baf_dev2_dflt = args->query_sample.baf_dev2_dflt; + args->query_sample.baf_dev2_dflt *= args->query_sample.baf_dev2_dflt; + args->control_sample.baf_dev2_dflt *= args->control_sample.baf_dev2_dflt; + break; + case 'k': + args->query_sample.lrr_dev2 = strtod(optarg,&tmp); + if ( *tmp ) + { + if ( *tmp!=',') error("Could not parse: -k %s\n", optarg); + args->control_sample.lrr_dev2 = strtod(tmp+1,&tmp); + if ( *tmp ) error("Could not parse: -d %s\n", optarg); + } + else + args->control_sample.lrr_dev2 = args->query_sample.lrr_dev2; + args->query_sample.lrr_dev2 *= args->query_sample.lrr_dev2; + args->control_sample.lrr_dev2 *= args->control_sample.lrr_dev2; + break; + case 'a': + args->query_sample.cell_frac_dflt = strtod(optarg,&tmp); + if ( *tmp ) + { + if ( *tmp!=',') error("Could not parse: -a %s\n", optarg); + args->control_sample.cell_frac_dflt = strtod(tmp+1,&tmp); + if ( *tmp ) error("Could not parse: -a %s\n", optarg); + } + break; + case 'W': + args->baum_welch_th = strtod(optarg,&tmp); + if ( *tmp ) error("Could not parse: -W %s\n", optarg); + break; + case 'e': + args->err_prob = strtod(optarg,&tmp); + if ( *tmp ) error("Could not parse: -e %s\n", optarg); + break; + case 'b': + args->baf_bias = strtod(optarg,&tmp); + if ( *tmp ) error("Could not parse: -b %s\n", optarg); + break; + case 'x': + args->ij_prob = strtod(optarg,&tmp); + if ( *tmp ) error("Could not parse: -x %s\n", optarg); + break; + case 'P': + args->same_prob = strtod(optarg,&tmp); + if ( *tmp ) error("Could not parse: -P %s\n", optarg); + break; + case 'l': + args->lrr_bias = strtod(optarg,&tmp); + if ( *tmp ) error("Could not parse: -l %s\n", optarg); + break; + case 'p': + args->plot_th = strtod(optarg,&tmp); + if ( *tmp ) error("Could not parse: -p %s\n", optarg); + break; + case 'o': args->output_dir = optarg; break; + case 's': args->query_sample.name = strdup(optarg); break; + case 'c': args->control_sample.name = optarg; break; + case 't': args->targets_list = optarg; break; + case 'T': args->targets_list = optarg; targets_is_file = 1; break; + case 'r': args->regions_list = optarg; break; + case 'R': args->regions_list = optarg; regions_is_file = 1; break; + case 'h': + case '?': usage(args); break; + default: error("Unknown argument: %s\n", optarg); + } + } + + char *fname = NULL; + if ( optind>=argc ) + { + if ( !isatty(fileno((FILE *)stdin)) ) fname = "-"; + } + else fname = argv[optind]; + if ( !fname ) usage(args); + + if ( !args->output_dir ) error("Expected -o option\n"); + if ( args->regions_list ) + { + if ( bcf_sr_set_regions(args->files, args->regions_list, regions_is_file)<0 ) + error("Failed to read the regions: %s\n", args->regions_list); + } + if ( args->targets_list ) + { + if ( bcf_sr_set_targets(args->files, args->targets_list, targets_is_file, 0)<0 ) + error("Failed to read the targets: %s\n", args->targets_list); + } + if ( args->af_fname ) + { + if ( bcf_sr_set_targets(args->files, args->af_fname, 1, 3)<0 ) + error("Failed to read the targets: %s\n", args->af_fname); + } + if ( !bcf_sr_add_reader(args->files, fname) ) error("Failed to open %s: %s\n", fname,bcf_sr_strerror(args->files->errnum)); + + init_data(args); + while ( bcf_sr_next_line(args->files) ) + { + bcf1_t *line = bcf_sr_get_line(args->files,0); + cnv_next_line(args, line); + } + cnv_next_line(args, NULL); + create_plots(args); + fprintf(stderr,"Number of lines: total/processed: %d/%d\n", args->ntot,args->nused); + destroy_data(args); + free(args); + return 0; +} + + diff --git a/vcfconcat.c b/vcfconcat.c new file mode 100644 index 0000000..3345c20 --- /dev/null +++ b/vcfconcat.c @@ -0,0 +1,825 @@ +/* vcfconcat.c -- Concatenate or combine VCF/BCF files. + + Copyright (C) 2013-2015 Genome Research Ltd. + + Author: Petr Danecek + +Permission is hereby granted, free of charge, to any person obtaining a copy +of this software and associated documentation files (the "Software"), to deal +in the Software without restriction, including without limitation the rights +to use, copy, modify, merge, publish, distribute, sublicense, and/or sell +copies of the Software, and to permit persons to whom the Software is +furnished to do so, subject to the following conditions: + +The above copyright notice and this permission notice shall be included in +all copies or substantial portions of the Software. + +THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE +AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER +LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, +OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN +THE SOFTWARE. */ + +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include // for hts_get_bgzfp() +#include "bcftools.h" + +typedef struct _args_t +{ + bcf_srs_t *files; + htsFile *out_fh; + int output_type, n_threads, record_cmd_line; + bcf_hdr_t *out_hdr; + int *seen_seq; + + // phasing + int *start_pos, start_tid, ifname; + int *swap_phase, nswap, *nmatch, *nmism; + bcf1_t **buf; + int nbuf, mbuf, prev_chr, min_PQ, prev_pos_check; + int32_t *GTa, *GTb, mGTa, mGTb, *phase_qual, *phase_set; + + char **argv, *output_fname, *file_list, **fnames, *remove_dups, *regions_list; + int argc, nfnames, allow_overlaps, phased_concat, regions_is_file; + int compact_PS, phase_set_changed, naive_concat; +} +args_t; + +static void init_data(args_t *args) +{ + bcf1_t *line = NULL; + + // With phased concat, the chunks overlap and come in the right order. To + // avoid opening all files at once, store start positions to recognise need + // for the next one. This way we can keep only two open chunks at once. + if ( args->phased_concat ) + { + args->start_pos = (int*) malloc(sizeof(int)*args->nfnames); + line = bcf_init(); + } + + kstring_t str = {0,0,0}; + int i, prev_chrid = -1; + for (i=0; infnames; i++) + { + htsFile *fp = hts_open(args->fnames[i], "r"); if ( !fp ) error("Failed to open: %s\n", args->fnames[i]); + bcf_hdr_t *hdr = bcf_hdr_read(fp); if ( !hdr ) error("Failed to parse header: %s\n", args->fnames[i]); + args->out_hdr = bcf_hdr_merge(args->out_hdr,hdr); + if ( bcf_hdr_nsamples(hdr) != bcf_hdr_nsamples(args->out_hdr) ) + error("Different number of samples in %s. Perhaps \"bcftools merge\" is what you are looking for?\n", args->fnames[i]); + + int j; + for (j=0; jout_hdr->samples[j],hdr->samples[j]) ) + error("Different sample names in %s. Perhaps \"bcftools merge\" is what you are looking for?\n", args->fnames[i]); + + if ( args->phased_concat ) + { + int ret = bcf_read(fp, hdr, line); + if ( ret!=0 ) args->start_pos[i] = -2; // empty file + else + { + int chrid = bcf_hdr_id2int(args->out_hdr,BCF_DT_CTG,bcf_seqname(hdr,line)); + args->start_pos[i] = chrid==prev_chrid ? line->pos : -1; + prev_chrid = chrid; + } + } + bcf_hdr_destroy(hdr); + hts_close(fp); + } + free(str.s); + if ( line ) bcf_destroy(line); + + args->seen_seq = (int*) calloc(args->out_hdr->n[BCF_DT_CTG],sizeof(int)); + + if ( args->phased_concat ) + { + bcf_hdr_append(args->out_hdr,"##FORMAT="); + bcf_hdr_append(args->out_hdr,"##FORMAT="); + } + if (args->record_cmd_line) bcf_hdr_append_version(args->out_hdr, args->argc, args->argv, "bcftools_concat"); + args->out_fh = hts_open(args->output_fname,hts_bcf_wmode(args->output_type)); + if ( args->out_fh == NULL ) error("Can't write to \"%s\": %s\n", args->output_fname, strerror(errno)); + if ( args->n_threads ) hts_set_threads(args->out_fh, args->n_threads); + + bcf_hdr_write(args->out_fh, args->out_hdr); + + if ( args->allow_overlaps ) + { + args->files = bcf_sr_init(); + args->files->require_index = 1; + if ( args->regions_list ) + { + if ( bcf_sr_set_regions(args->files, args->regions_list, args->regions_is_file)<0 ) + error("Failed to read the regions: %s\n", args->regions_list); + } + if ( args->remove_dups ) + { + if ( !strcmp(args->remove_dups,"snps") ) args->files->collapse |= COLLAPSE_SNPS; + else if ( !strcmp(args->remove_dups,"indels") ) args->files->collapse |= COLLAPSE_INDELS; + else if ( !strcmp(args->remove_dups,"both") ) args->files->collapse |= COLLAPSE_SNPS | COLLAPSE_INDELS; + else if ( !strcmp(args->remove_dups,"any") ) args->files->collapse |= COLLAPSE_ANY; + else if ( !strcmp(args->remove_dups,"all") ) args->files->collapse |= COLLAPSE_ANY; + else if ( !strcmp(args->remove_dups,"none") ) args->files->collapse = COLLAPSE_NONE; + else error("The -D string \"%s\" not recognised.\n", args->remove_dups); + } + for (i=0; infnames; i++) + if ( !bcf_sr_add_reader(args->files,args->fnames[i]) ) error("Failed to open %s: %s\n", args->fnames[i],bcf_sr_strerror(args->files->errnum)); + } + else if ( args->phased_concat ) + { + // Remove empty files from the list + int nok = 0; + while (1) + { + while ( noknfnames && args->start_pos[nok]!=-2 ) nok++; + if ( nok==args->nfnames ) break; + + i = nok; + while ( infnames && args->start_pos[i]==-2 ) i++; + if ( i==args->nfnames ) break; + + int tmp = args->start_pos[nok]; args->start_pos[nok] = args->start_pos[i]; args->start_pos[i] = tmp; + char *str = args->fnames[nok]; args->fnames[nok] = args->fnames[i]; args->fnames[i] = str; + } + for (i=nok; infnames; i++) free(args->fnames[i]); + args->nfnames = nok; + + for (i=1; infnames; i++) + if ( args->start_pos[i-1]!=-1 && args->start_pos[i]!=-1 && args->start_pos[i]start_pos[i-1] ) + error("The files not in ascending order: %d in %s, %d in %s\n", args->start_pos[i-1]+1,args->fnames[i-1],args->start_pos[i]+1,args->fnames[i]); + + args->prev_chr = -1; + args->swap_phase = (int*) calloc(bcf_hdr_nsamples(args->out_hdr),sizeof(int)); + args->nmatch = (int*) calloc(bcf_hdr_nsamples(args->out_hdr),sizeof(int)); + args->nmism = (int*) calloc(bcf_hdr_nsamples(args->out_hdr),sizeof(int)); + args->phase_qual = (int32_t*) malloc(bcf_hdr_nsamples(args->out_hdr)*sizeof(int32_t)); + args->phase_set = (int32_t*) malloc(bcf_hdr_nsamples(args->out_hdr)*sizeof(int32_t)); + args->files = bcf_sr_init(); + args->files->require_index = 1; + args->ifname = 0; + } +} + +static void destroy_data(args_t *args) +{ + int i; + for (i=0; infnames; i++) free(args->fnames[i]); + free(args->fnames); + if ( args->files ) bcf_sr_destroy(args->files); + if ( args->out_fh ) + { + if ( hts_close(args->out_fh)!=0 ) error("hts_close error\n"); + } + if ( args->out_hdr ) bcf_hdr_destroy(args->out_hdr); + free(args->seen_seq); + free(args->start_pos); + free(args->swap_phase); + for (i=0; imbuf; i++) bcf_destroy(args->buf[i]); + free(args->buf); + free(args->GTa); + free(args->GTb); + free(args->nmatch); + free(args->nmism); + free(args->phase_qual); + free(args->phase_set); +} + +int vcf_write_line(htsFile *fp, kstring_t *line); + +#define SWAP(type_t, a, b) { type_t t = a; a = b; b = t; } +static void phase_update(args_t *args, bcf_hdr_t *hdr, bcf1_t *rec) +{ + int i, nGTs = bcf_get_genotypes(hdr, rec, &args->GTa, &args->mGTa); + if ( nGTs <= 0 ) return; // GT field is not present + for (i=0; iswap_phase[i] ) continue; + int *gt = &args->GTa[i*2]; + if ( bcf_gt_is_missing(gt[0]) || gt[1]==bcf_int32_vector_end ) continue; + SWAP(int, gt[0], gt[1]); + gt[1] |= 1; + } + bcf_update_genotypes(hdr,rec,args->GTa,nGTs); +} + +static void phased_flush(args_t *args) +{ + if ( !args->nbuf ) return; + + bcf_hdr_t *ahdr = args->files->readers[0].header; + bcf_hdr_t *bhdr = args->files->readers[1].header; + + int i, j, nsmpl = bcf_hdr_nsamples(args->out_hdr); + static int gt_absent_warned = 0; + + for (i=0; inbuf; i+=2) + { + bcf1_t *arec = args->buf[i]; + bcf1_t *brec = args->buf[i+1]; + + int nGTs = bcf_get_genotypes(ahdr, arec, &args->GTa, &args->mGTa); + if ( nGTs < 0 ) + { + if ( !gt_absent_warned ) + { + fprintf(stderr,"GT is not present at %s:%d. (This warning is printed only once.)\n", bcf_seqname(ahdr,arec), arec->pos+1); + gt_absent_warned = 1; + } + continue; + } + if ( nGTs != 2*nsmpl ) continue; // not diploid + nGTs = bcf_get_genotypes(bhdr, brec, &args->GTb, &args->mGTb); + if ( nGTs < 0 ) + { + if ( !gt_absent_warned ) + { + fprintf(stderr,"GT is not present at %s:%d. (This warning is printed only once.)\n", bcf_seqname(bhdr,brec), brec->pos+1); + gt_absent_warned = 1; + } + continue; + } + if ( nGTs != 2*nsmpl ) continue; // not diploid + + for (j=0; jGTa[j*2]; + int *gtb = &args->GTb[j*2]; + if ( gta[1]==bcf_int32_vector_end || gtb[1]==bcf_int32_vector_end ) continue; + if ( bcf_gt_is_missing(gta[0]) || bcf_gt_is_missing(gta[1]) || bcf_gt_is_missing(gtb[0]) || bcf_gt_is_missing(gtb[1]) ) continue; + if ( !bcf_gt_is_phased(gta[1]) || !bcf_gt_is_phased(gtb[1]) ) continue; + if ( bcf_gt_allele(gta[0])==bcf_gt_allele(gta[1]) || bcf_gt_allele(gtb[0])==bcf_gt_allele(gtb[1]) ) continue; + if ( bcf_gt_allele(gta[0])==bcf_gt_allele(gtb[0]) && bcf_gt_allele(gta[1])==bcf_gt_allele(gtb[1]) ) + { + if ( args->swap_phase[j] ) args->nmism[j]++; else args->nmatch[j]++; + } + if ( bcf_gt_allele(gta[0])==bcf_gt_allele(gtb[1]) && bcf_gt_allele(gta[1])==bcf_gt_allele(gtb[0]) ) + { + if ( args->swap_phase[j] ) args->nmatch[j]++; else args->nmism[j]++; + } + } + } + for (i=0; inbuf/2; i+=2) + { + bcf1_t *arec = args->buf[i]; + bcf_translate(args->out_hdr, args->files->readers[0].header, arec); + if ( args->nswap ) + phase_update(args, args->out_hdr, arec); + if ( !args->compact_PS || args->phase_set_changed ) + { + bcf_update_format_int32(args->out_hdr,arec,"PS",args->phase_set,nsmpl); + args->phase_set_changed = 0; + } + bcf_write(args->out_fh, args->out_hdr, arec); + + if ( arec->pos < args->prev_pos_check ) error("FIXME, disorder: %s:%d vs %d [1]\n", bcf_seqname(args->files->readers[0].header,arec),arec->pos+1,args->prev_pos_check+1); + args->prev_pos_check = arec->pos; + } + args->nswap = 0; + for (j=0; jnmatch[j] >= args->nmism[j] ) + args->swap_phase[j] = 0; + else + { + args->swap_phase[j] = 1; + args->nswap++; + } + if ( args->nmatch[j] && args->nmism[j] ) + { + // Entropy-inspired quality. The factor 0.7 shifts and scales to (0,1) + double f = (double)args->nmatch[j]/(args->nmatch[j]+args->nmism[j]); + args->phase_qual[j] = 99*(0.7 + f*log(f) + (1-f)*log(1-f))/0.7; + } + else + args->phase_qual[j] = 99; + args->nmatch[j] = 0; + args->nmism[j] = 0; + } + int PQ_printed = 0; + for (; inbuf; i+=2) + { + bcf1_t *brec = args->buf[i+1]; + bcf_translate(args->out_hdr, args->files->readers[1].header, brec); + if ( !PQ_printed ) + { + bcf_update_format_int32(args->out_hdr,brec,"PQ",args->phase_qual,nsmpl); + PQ_printed = 1; + for (j=0; jphase_qual[j] < args->min_PQ ) + { + args->phase_set[j] = brec->pos+1; + args->phase_set_changed = 1; + } + else if ( args->compact_PS ) args->phase_set[j] = bcf_int32_missing; + } + if ( args->nswap ) + phase_update(args, args->out_hdr, brec); + if ( !args->compact_PS || args->phase_set_changed ) + { + bcf_update_format_int32(args->out_hdr,brec,"PS",args->phase_set,nsmpl); + args->phase_set_changed = 0; + } + bcf_write(args->out_fh, args->out_hdr, brec); + + if ( brec->pos < args->prev_pos_check ) error("FIXME, disorder: %s:%d vs %d [2]\n", bcf_seqname(args->files->readers[1].header,brec),brec->pos+1,args->prev_pos_check+1); + args->prev_pos_check = brec->pos; + } + args->nbuf = 0; +} + +static void phased_push(args_t *args, bcf1_t *arec, bcf1_t *brec) +{ + if ( arec && arec->errcode ) + error("Parse error at %s:%d, cannot proceed: %s\n", bcf_seqname(args->files->readers[0].header,arec),arec->pos+1, args->files->readers[0].fname); + if ( brec && brec->errcode ) + error("Parse error at %s:%d, cannot proceed: %s\n", bcf_seqname(args->files->readers[1].header,brec),brec->pos+1, args->files->readers[1].fname); + + int i, nsmpl = bcf_hdr_nsamples(args->out_hdr); + int chr_id = bcf_hdr_name2id(args->out_hdr, bcf_seqname(args->files->readers[0].header,arec)); + if ( args->prev_chr<0 || args->prev_chr!=chr_id ) + { + if ( args->prev_chr>=0 ) phased_flush(args); + + for (i=0; iphase_set[i] = arec->pos+1; + args->phase_set_changed = 1; + + if ( args->seen_seq[chr_id] ) error("The chromosome block %s is not contiguous\n", bcf_seqname(args->files->readers[0].header,arec)); + args->seen_seq[chr_id] = 1; + args->prev_chr = chr_id; + args->prev_pos_check = -1; + } + + if ( !brec ) + { + bcf_translate(args->out_hdr, args->files->readers[0].header, arec); + if ( args->nswap ) + phase_update(args, args->out_hdr, arec); + if ( !args->compact_PS || args->phase_set_changed ) + { + bcf_update_format_int32(args->out_hdr,arec,"PS",args->phase_set,nsmpl); + args->phase_set_changed = 0; + } + bcf_write(args->out_fh, args->out_hdr, arec); + + if ( arec->pos < args->prev_pos_check ) + error("FIXME, disorder: %s:%d in %s vs %d written [3]\n", bcf_seqname(args->files->readers[0].header,arec), arec->pos+1,args->files->readers[0].fname, args->prev_pos_check+1); + args->prev_pos_check = arec->pos; + return; + } + + int m = args->mbuf; + args->nbuf += 2; + hts_expand(bcf1_t*,args->nbuf,args->mbuf,args->buf); + for (i=m; imbuf; i++) + args->buf[i] = bcf_init1(); + + SWAP(bcf1_t*, args->files->readers[0].buffer[0], args->buf[args->nbuf-2]); + SWAP(bcf1_t*, args->files->readers[1].buffer[0], args->buf[args->nbuf-1]); +} + +static void concat(args_t *args) +{ + int i; + if ( args->phased_concat ) // phased concat + { + // keep only two open files at a time + while ( args->ifname < args->nfnames ) + { + int new_file = 0; + while ( args->files->nreaders < 2 && args->ifname < args->nfnames ) + { + if ( !bcf_sr_add_reader(args->files,args->fnames[args->ifname]) ) error("Failed to open %s: %s\n", args->fnames[args->ifname],bcf_sr_strerror(args->files->errnum)); + new_file = 1; + + args->ifname++; + if ( args->start_pos[args->ifname-1]==-1 ) break; // new chromosome, start with only one file open + if ( args->ifname < args->nfnames && args->start_pos[args->ifname]==-1 ) break; // next file starts on a different chromosome + } + + // is there a line from the previous run? Seek the newly opened reader to that position + int seek_pos = -1; + int seek_chr = -1; + if ( bcf_sr_has_line(args->files,0) ) + { + bcf1_t *line = bcf_sr_get_line(args->files,0); + bcf_sr_seek(args->files, bcf_seqname(args->files->readers[0].header,line), line->pos); + seek_pos = line->pos; + seek_chr = bcf_hdr_name2id(args->out_hdr, bcf_seqname(args->files->readers[0].header,line)); + } + else if ( new_file ) + bcf_sr_seek(args->files,NULL,0); // set to start + + int nret; + while ( (nret = bcf_sr_next_line(args->files)) ) + { + if ( !bcf_sr_has_line(args->files,0) ) // no input from the first reader + { + // We are assuming that there is a perfect overlap, sites which are not present in both files are dropped + if ( ! bcf_sr_region_done(args->files,0) ) continue; + + phased_flush(args); + bcf_sr_remove_reader(args->files, 0); + } + + // Get a line to learn about current position + for (i=0; ifiles->nreaders; i++) + if ( bcf_sr_has_line(args->files,i) ) break; + bcf1_t *line = bcf_sr_get_line(args->files,i); + + // This can happen after bcf_sr_seek: indel may start before the coordinate which we seek to. + if ( seek_chr>=0 && seek_pos>line->pos && seek_chr==bcf_hdr_name2id(args->out_hdr, bcf_seqname(args->files->readers[i].header,line)) ) continue; + seek_pos = seek_chr = -1; + + // Check if the position overlaps with the next, yet unopened, reader + int must_seek = 0; + while ( args->ifname < args->nfnames && args->start_pos[args->ifname]!=-1 && line->pos >= args->start_pos[args->ifname] ) + { + must_seek = 1; + if ( !bcf_sr_add_reader(args->files,args->fnames[args->ifname]) ) error("Failed to open %s: %s\n", args->fnames[args->ifname],bcf_sr_strerror(args->files->errnum)); + args->ifname++; + } + if ( must_seek ) + { + bcf_sr_seek(args->files, bcf_seqname(args->files->readers[i].header,line), line->pos); + seek_pos = line->pos; + seek_chr = bcf_hdr_name2id(args->out_hdr, bcf_seqname(args->files->readers[i].header,line)); + continue; + } + + // We are assuming that there is a perfect overlap, sites which are not present in both files are dropped + if ( args->files->nreaders>1 && !bcf_sr_has_line(args->files,1) && !bcf_sr_region_done(args->files,1) ) continue; + + phased_push(args, bcf_sr_get_line(args->files,0), args->files->nreaders>1 ? bcf_sr_get_line(args->files,1) : NULL); + } + + if ( args->files->nreaders ) + { + phased_flush(args); + while ( args->files->nreaders ) + bcf_sr_remove_reader(args->files, 0); + } + } + } + else if ( args->files ) // combining overlapping files, using synced reader + { + while ( bcf_sr_next_line(args->files) ) + { + for (i=0; ifiles->nreaders; i++) + { + bcf1_t *line = bcf_sr_get_line(args->files,i); + if ( !line ) continue; + bcf_translate(args->out_hdr, args->files->readers[i].header, line); + bcf_write1(args->out_fh, args->out_hdr, line); + if ( args->remove_dups ) break; + } + } + } + else // concatenating + { + kstring_t tmp = {0,0,0}; + int prev_chr_id = -1, prev_pos; + bcf1_t *line = bcf_init(); + for (i=0; infnames; i++) + { + htsFile *fp = hts_open(args->fnames[i], "r"); if ( !fp ) error("Failed to open: %s\n", args->fnames[i]); + bcf_hdr_t *hdr = bcf_hdr_read(fp); if ( !hdr ) error("Failed to parse header: %s\n", args->fnames[i]); + if ( !fp->is_bin && args->output_type&FT_VCF ) + { + line->max_unpack = BCF_UN_STR; + // if VCF is on both input and output, avoid VCF to BCF conversion + while ( hts_getline(fp, KS_SEP_LINE, &fp->line) >=0 ) + { + char *str = fp->line.s; + while ( *str && *str!='\t' ) str++; + tmp.l = 0; + kputsn(fp->line.s,str-fp->line.s,&tmp); + int chr_id = bcf_hdr_name2id(args->out_hdr, tmp.s); + if ( chr_id<0 ) error("The sequence \"%s\" not defined in the header: %s\n(Quick workaround: index the file.)\n", tmp.s, args->fnames[i]); + if ( prev_chr_id!=chr_id ) + { + prev_pos = -1; + if ( args->seen_seq[chr_id] ) + error("\nThe chromosome block %s is not contiguous, consider running with -a.\n", tmp.s); + } + char *end; + int pos = strtol(str+1,&end,10) - 1; + if ( end==str+1 ) error("Could not parse line: %s\n", fp->line.s); + if ( prev_pos > pos ) + error("The chromosome block %s is not sorted, consider running with -a.\n", tmp.s); + args->seen_seq[chr_id] = 1; + prev_chr_id = chr_id; + + if ( vcf_write_line(args->out_fh, &fp->line)!=0 ) error("Failed to write %d bytes\n", fp->line.l); + } + } + else + { + // BCF conversion is required + line->max_unpack = 0; + while ( bcf_read(fp, hdr, line)==0 ) + { + bcf_translate(args->out_hdr, hdr, line); + + if ( prev_chr_id!=line->rid ) + { + prev_pos = -1; + if ( args->seen_seq[line->rid] ) + error("\nThe chromosome block %s is not contiguous, consider running with -a.\n", bcf_seqname(args->out_hdr, line)); + } + if ( prev_pos > line->pos ) + error("The chromosome block %s is not sorted, consider running with -a.\n", bcf_seqname(args->out_hdr, line)); + args->seen_seq[line->rid] = 1; + prev_chr_id = line->rid; + + if ( bcf_write(args->out_fh, args->out_hdr, line)!=0 ) error("Failed to write\n"); + } + } + bcf_hdr_destroy(hdr); + hts_close(fp); + } + bcf_destroy(line); + free(tmp.s); + } +} + +int print_vcf_gz_header(BGZF *fp, BGZF *bgzf_out, int print_header, kstring_t *tmp) +{ + char *buffer = (char*) fp->uncompressed_block; + + // Read the header and find the position of the data block + if ( buffer[0]!='#' ) error("Could not parse the header, expected '#', found '%c'\n", buffer[0]); + + int nskip = 1; // end of the header in the current uncompressed block + while (1) + { + if ( buffer[nskip]=='\n' ) + { + nskip++; + if ( nskip>=fp->block_length ) + { + kputsn(buffer,nskip,tmp); + if ( bgzf_read_block(fp) != 0 ) return -1; + if ( !fp->block_length ) break; + nskip = 0; + } + // The header has finished + if ( buffer[nskip]!='#' ) + { + kputsn(buffer,nskip,tmp); + break; + } + } + nskip++; + if ( nskip>=fp->block_length ) + { + kputsn(buffer,fp->block_length,tmp); + if ( bgzf_read_block(fp) != 0 ) return -1; + if ( !fp->block_length ) break; + nskip = 0; + } + } + if ( print_header ) + { + if ( bgzf_write(bgzf_out,tmp->s,tmp->l) != tmp->l ) error("Failed to write %d bytes\n", tmp->l); + tmp->l = 0; + } + return nskip; +} + +static inline int unpackInt16(const uint8_t *buffer) +{ + return buffer[0] | buffer[1] << 8; +} +static int check_header(const uint8_t *header) +{ + if ( header[0] != 31 || header[1] != 139 || header[2] != 8 ) return -2; + return ((header[3] & 4) != 0 + && unpackInt16((uint8_t*)&header[10]) == 6 + && header[12] == 'B' && header[13] == 'C' + && unpackInt16((uint8_t*)&header[14]) == 2) ? 0 : -1; +} +static void naive_concat(args_t *args) +{ + // only compressed BCF atm + BGZF *bgzf_out = bgzf_open(args->output_fname,"w");; + + const size_t page_size = BGZF_MAX_BLOCK_SIZE; + uint8_t *buf = (uint8_t*) malloc(page_size); + kstring_t tmp = {0,0,0}; + int i, file_types = 0; + for (i=0; infnames; i++) + { + htsFile *hts_fp = hts_open(args->fnames[i],"r"); + if ( !hts_fp ) error("Failed to open: %s\n", args->fnames[i]); + htsFormat type = *hts_get_format(hts_fp); + + if ( type.compression!=bgzf ) + error("The --naive option works only for compressed BCFs or VCFs, sorry :-/\n"); + file_types |= type.format==vcf ? 1 : 2; + if ( file_types==3 ) + error("The --naive option works only for compressed files of the same type, all BCFs or all VCFs :-/\n"); + + BGZF *fp = hts_get_bgzfp(hts_fp); + if ( !fp || bgzf_read_block(fp) != 0 || !fp->block_length ) + error("Failed to read %s: %s\n", args->fnames[i], strerror(errno)); + + int nskip; + if ( type.format==bcf ) + { + uint8_t magic[5]; + if ( bgzf_read(fp, magic, 5) != 5 ) error("Failed to read the BCF header in %s\n", args->fnames[i]); + if (strncmp((char*)magic, "BCF\2\2", 5) != 0) error("Invalid BCF magic string in %s\n", args->fnames[i]); + + if ( bgzf_read(fp, &tmp.l, 4) != 4 ) error("Failed to read the BCF header in %s\n", args->fnames[i]); + hts_expand(char,tmp.l,tmp.m,tmp.s); + if ( bgzf_read(fp, tmp.s, tmp.l) != tmp.l ) error("Failed to read the BCF header in %s\n", args->fnames[i]); + + // write only the first header + if ( i==0 ) + { + if ( bgzf_write(bgzf_out, "BCF\2\2", 5) !=5 ) error("Failed to write %d bytes to %s\n", 5,args->output_fname); + if ( bgzf_write(bgzf_out, &tmp.l, 4) !=4 ) error("Failed to write %d bytes to %s\n", 4,args->output_fname); + if ( bgzf_write(bgzf_out, tmp.s, tmp.l) != tmp.l) error("Failed to write %d bytes to %s\n", tmp.l,args->output_fname); + } + nskip = fp->block_offset; + } + else + { + nskip = print_vcf_gz_header(fp, bgzf_out, i==0?1:0, &tmp); + if ( nskip==-1 ) error("Error reading %s\n", args->fnames[i]); + } + + // Output all non-header data that were read together with the header block + if ( fp->block_length - nskip > 0 ) + { + if ( bgzf_write(bgzf_out, (char *)fp->uncompressed_block+nskip, fp->block_length-nskip)<0 ) error("Error: %d\n",fp->errcode); + } + if ( bgzf_flush(bgzf_out)<0 ) error("Error: %d\n",bgzf_out->errcode); + + + // Stream the rest of the file as it is, without recompressing, but remove BGZF EOF blocks + // The final bgzf eof block will be added by bgzf_close. + ssize_t nread, nblock, nwr; + const int nheader = 18, neof = 28; + const uint8_t *eof = (uint8_t*) "\037\213\010\4\0\0\0\0\0\377\6\0\102\103\2\0\033\0\3\0\0\0\0\0\0\0\0\0"; + while (1) + { + nread = bgzf_raw_read(fp, buf, nheader); + if ( !nread ) break; + if ( nread != nheader || check_header(buf)!=0 ) error("Could not parse the header of a bgzf block: %s\n",args->fnames[i]); + nblock = unpackInt16(buf+16) + 1; + assert( nblock <= page_size && nblock >= nheader ); + nread += bgzf_raw_read(fp, buf+nheader, nblock - nheader); + if ( nread!=nblock ) error("Could not read %d bytes: %s\n",nblock,args->fnames[i]); + if ( nread==neof && !memcmp(buf,eof,neof) ) continue; + nwr = bgzf_raw_write(bgzf_out, buf, nread); + if ( nwr != nread ) error("Write failed, wrote %d instead of %d bytes.\n", nwr,(int)nread); + } + if (hts_close(hts_fp)) error("Close failed: %s\n",args->fnames[i]); + } + free(buf); + free(tmp.s); + if (bgzf_close(bgzf_out) < 0) error("Error: %d\n",bgzf_out->errcode); +} + +static void usage(args_t *args) +{ + fprintf(stderr, "\n"); + fprintf(stderr, "About: Concatenate or combine VCF/BCF files. All source files must have the same sample\n"); + fprintf(stderr, " columns appearing in the same order. The program can be used, for example, to\n"); + fprintf(stderr, " concatenate chromosome VCFs into one VCF, or combine a SNP VCF and an indel\n"); + fprintf(stderr, " VCF into one. The input files must be sorted by chr and position. The files\n"); + fprintf(stderr, " must be given in the correct order to produce sorted VCF on output unless\n"); + fprintf(stderr, " the -a, --allow-overlaps option is specified. With the --naive option, the files\n"); + fprintf(stderr, " are concatenated without being recompressed, which is very fast but dangerous\n"); + fprintf(stderr, " if the BCF headers differ.\n"); + fprintf(stderr, "Usage: bcftools concat [options] [ [...]]\n"); + fprintf(stderr, "\n"); + fprintf(stderr, "Options:\n"); + fprintf(stderr, " -a, --allow-overlaps First coordinate of the next file can precede last record of the current file.\n"); + fprintf(stderr, " -c, --compact-PS Do not output PS tag at each site, only at the start of a new phase set block.\n"); + fprintf(stderr, " -d, --rm-dups Output duplicate records present in multiple files only once: \n"); + fprintf(stderr, " -D, --remove-duplicates Alias for -d none\n"); + fprintf(stderr, " -f, --file-list Read the list of files from a file.\n"); + fprintf(stderr, " -l, --ligate Ligate phased VCFs by matching phase at overlapping haplotypes\n"); + fprintf(stderr, " --no-version Do not append version and command line to the header\n"); + fprintf(stderr, " -n, --naive Concatenate files without recompression (dangerous, use with caution)\n"); + fprintf(stderr, " -o, --output Write output to a file [standard output]\n"); + fprintf(stderr, " -O, --output-type b: compressed BCF, u: uncompressed BCF, z: compressed VCF, v: uncompressed VCF [v]\n"); + fprintf(stderr, " -q, --min-PQ Break phase set if phasing quality is lower than [30]\n"); + fprintf(stderr, " -r, --regions Restrict to comma-separated list of regions\n"); + fprintf(stderr, " -R, --regions-file Restrict to regions listed in a file\n"); + fprintf(stderr, " --threads Number of extra output compression threads [0]\n"); + fprintf(stderr, "\n"); + exit(1); +} + +int main_vcfconcat(int argc, char *argv[]) +{ + int c; + args_t *args = (args_t*) calloc(1,sizeof(args_t)); + args->argc = argc; args->argv = argv; + args->output_fname = "-"; + args->output_type = FT_VCF; + args->n_threads = 0; + args->record_cmd_line = 1; + args->min_PQ = 30; + + static struct option loptions[] = + { + {"naive",no_argument,NULL,'n'}, + {"compact-PS",no_argument,NULL,'c'}, + {"regions",required_argument,NULL,'r'}, + {"regions-file",required_argument,NULL,'R'}, + {"remove-duplicates",no_argument,NULL,'D'}, + {"rm-dups",required_argument,NULL,'d'}, + {"allow-overlaps",no_argument,NULL,'a'}, + {"ligate",no_argument,NULL,'l'}, + {"output",required_argument,NULL,'o'}, + {"output-type",required_argument,NULL,'O'}, + {"threads",required_argument,NULL,9}, + {"file-list",required_argument,NULL,'f'}, + {"min-PQ",required_argument,NULL,'q'}, + {"no-version",no_argument,NULL,8}, + {NULL,0,NULL,0} + }; + char *tmp; + while ((c = getopt_long(argc, argv, "h:?o:O:f:alq:Dd:r:R:cn",loptions,NULL)) >= 0) + { + switch (c) { + case 'c': args->compact_PS = 1; break; + case 'r': args->regions_list = optarg; break; + case 'R': args->regions_list = optarg; args->regions_is_file = 1; break; + case 'd': args->remove_dups = optarg; break; + case 'D': args->remove_dups = "none"; break; + case 'q': + args->min_PQ = strtol(optarg,&tmp,10); + if ( *tmp ) error("Could not parse argument: --min-PQ %s\n", optarg); + break; + case 'n': args->naive_concat = 1; break; + case 'a': args->allow_overlaps = 1; break; + case 'l': args->phased_concat = 1; break; + case 'f': args->file_list = optarg; break; + case 'o': args->output_fname = optarg; break; + case 'O': + switch (optarg[0]) { + case 'b': args->output_type = FT_BCF_GZ; break; + case 'u': args->output_type = FT_BCF; break; + case 'z': args->output_type = FT_VCF_GZ; break; + case 'v': args->output_type = FT_VCF; break; + default: error("The output type \"%s\" not recognised\n", optarg); + }; + break; + case 9 : args->n_threads = strtol(optarg, 0, 0); break; + case 8 : args->record_cmd_line = 0; break; + case 'h': + case '?': usage(args); break; + default: error("Unknown argument: %s\n", optarg); + } + } + while ( optindnfnames++; + args->fnames = (char **)realloc(args->fnames,sizeof(char*)*args->nfnames); + args->fnames[args->nfnames-1] = strdup(argv[optind]); + optind++; + } + if ( args->allow_overlaps && args->phased_concat ) args->allow_overlaps = 0; + if ( args->compact_PS && !args->phased_concat ) error("The -c option is intended only with -l\n"); + if ( args->file_list ) + { + if ( args->nfnames ) error("Cannot combine -l with file names on command line.\n"); + args->fnames = hts_readlines(args->file_list, &args->nfnames); + if ( !args->fnames ) error("Could not read the file: %s\n", args->file_list); + } + if ( !args->nfnames ) usage(args); + if ( args->remove_dups && !args->allow_overlaps ) error("The -D option is supported only with -a\n"); + if ( args->regions_list && !args->allow_overlaps ) error("The -r/-R option is supported only with -a\n"); + if ( args->naive_concat ) + { + if ( args->allow_overlaps ) error("The option --naive cannot be combined with --allow-overlaps\n"); + if ( args->phased_concat ) error("The option --naive cannot be combined with --ligate\n"); + naive_concat(args); + destroy_data(args); + free(args); + return 0; + } + init_data(args); + concat(args); + destroy_data(args); + free(args); + return 0; +} diff --git a/vcfconvert.c b/vcfconvert.c new file mode 100644 index 0000000..f650bea --- /dev/null +++ b/vcfconvert.c @@ -0,0 +1,1530 @@ +/* vcfconvert.c -- convert between VCF/BCF and related formats. + + Copyright (C) 2013-2014 Genome Research Ltd. + + Author: Petr Danecek + +Permission is hereby granted, free of charge, to any person obtaining a copy +of this software and associated documentation files (the "Software"), to deal +in the Software without restriction, including without limitation the rights +to use, copy, modify, merge, publish, distribute, sublicense, and/or sell +copies of the Software, and to permit persons to whom the Software is +furnished to do so, subject to the following conditions: + +The above copyright notice and this permission notice shall be included in +all copies or substantial portions of the Software. + +THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE +AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER +LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, +OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN +THE SOFTWARE. */ + +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include "bcftools.h" +#include "filter.h" +#include "convert.h" +#include "tsv2vcf.h" + +// Logic of the filters: include or exclude sites which match the filters? +#define FLT_INCLUDE 1 +#define FLT_EXCLUDE 2 + +typedef struct _args_t args_t; +struct _args_t +{ + faidx_t *ref; + filter_t *filter; + char *filter_str; + int filter_logic; // include or exclude sites which match the filters? One of FLT_INCLUDE/FLT_EXCLUDE + convert_t *convert; + bcf_srs_t *files; + bcf_hdr_t *header; + void (*convert_func)(struct _args_t *); + struct { + int total, skipped, hom_rr, het_ra, hom_aa, het_aa, missing; + } n; + kstring_t str; + int32_t *gts; + float *flt; + int rev_als, output_vcf_ids, hap2dip, output_chrom_first_col; + int nsamples, *samples, sample_is_file, targets_is_file, regions_is_file, output_type; + char **argv, *sample_list, *targets_list, *regions_list, *tag, *columns; + char *outfname, *infname, *ref_fname, *sex_fname; + int argc, n_threads, record_cmd_line; +}; + +static void destroy_data(args_t *args) +{ + if ( args->ref ) fai_destroy(args->ref); + if ( args->convert) convert_destroy(args->convert); + if ( args->filter ) filter_destroy(args->filter); + free(args->samples); + if ( args->files ) bcf_sr_destroy(args->files); +} + +static void open_vcf(args_t *args, const char *format_str) +{ + args->files = bcf_sr_init(); + if ( args->n_threads && bcf_sr_set_threads(args->files, args->n_threads)!=0 ) + error("Could not initialize --threads %d\n", args->n_threads); + + if ( args->regions_list ) + { + if ( bcf_sr_set_regions(args->files, args->regions_list, args->regions_is_file)<0 ) + error("Failed to read the regions: %s\n", args->regions_list); + } + if ( args->targets_list ) + { + if ( bcf_sr_set_targets(args->files, args->targets_list, args->targets_is_file, 0)<0 ) + error("Failed to read the targets: %s\n", args->targets_list); + } + if ( !bcf_sr_add_reader(args->files, args->infname) ) + error("Failed to open %s: %s\n", args->infname,bcf_sr_strerror(args->files->errnum)); + + args->header = args->files->readers[0].header; + + if ( args->filter_str ) + args->filter = filter_init(args->header, args->filter_str); + + int i, nsamples = 0, *samples = NULL; + if ( args->sample_list && strcmp("-",args->sample_list) ) + { + for (i=0; ifiles->nreaders; i++) + { + int ret = bcf_hdr_set_samples(args->files->readers[i].header,args->sample_list,args->sample_is_file); + if ( ret<0 ) error("Error parsing the sample list\n"); + else if ( ret>0 ) error("Sample name mismatch: sample #%d not found in the header\n", ret); + } + + if ( args->sample_list[0]!='^' ) + { + // the sample ordering may be different if not negated + int n; + char **smpls = hts_readlist(args->sample_list, args->sample_is_file, &n); + if ( !smpls ) error("Could not parse %s\n", args->sample_list); + if ( n!=bcf_hdr_nsamples(args->files->readers[0].header) ) + error("The number of samples does not match, perhaps some are present multiple times?\n"); + nsamples = bcf_hdr_nsamples(args->files->readers[0].header); + samples = (int*) malloc(sizeof(int)*nsamples); + for (i=0; ifiles->readers[0].header, BCF_DT_SAMPLE,smpls[i]); + free(smpls[i]); + } + free(smpls); + } + } + if ( format_str ) args->convert = convert_init(args->header, samples, nsamples, format_str); + free(samples); +} + +static int tsv_setter_chrom_pos_ref_alt(tsv_t *tsv, bcf1_t *rec, void *usr) +{ + args_t *args = (args_t*) usr; + + char tmp, *se = tsv->ss, *ss = tsv->ss; + while ( se < tsv->se && *se!=':' ) se++; + if ( *se!=':' ) error("Could not parse CHROM in CHROM:POS_REF_ALT id: %s\n", tsv->ss); + tmp = *se; *se = 0; + rec->rid = bcf_hdr_name2id(args->header,ss); + if ( rec->rid<0 ) error("Could not determine sequence name or multiple sequences present: %s\n", tsv->ss); + *se = tmp; + + // POS + rec->pos = strtol(se+1,&ss,10); + if ( ss==se+1 ) error("Could not parse POS in CHROM:POS_REF_ALT: %s\n", tsv->ss); + rec->pos--; + + // REF,ALT + args->str.l = 0; + se = ++ss; + while ( se < tsv->se && *se!='_' ) se++; + if ( *se!='_' ) error("Could not parse REF in CHROM:POS_REF_ALT id: %s\n", tsv->ss); + kputsn(ss,se-ss,&args->str); + ss = ++se; + while ( se < tsv->se && *se!='_' && isspace(*tsv->se) ) se++; + if ( se < tsv->se && *se!='_' && isspace(*tsv->se) ) error("Could not parse ALT in CHROM:POS_REF_ALT id: %s\n", tsv->ss); + kputc(',',&args->str); + kputsn(ss,se-ss,&args->str); + bcf_update_alleles_str(args->header, rec, args->str.s); + + // END - optional + if (*se && *se=='_') { + long end = strtol(se+1,&ss,10); + if ( ss==se+1 ) error("Could not parse END in CHROM:POS_REF_ALT_END: %s\n", tsv->ss); + bcf_update_info_int32(args->header, rec, "END", &end, 1); + } + + return 0; +} +static int tsv_setter_verify_pos(tsv_t *tsv, bcf1_t *rec, void *usr) +{ + char *se; + int pos = strtol(tsv->ss,&se,10); + if ( tsv->ss==se ) error("Could not parse POS: %s\n", tsv->ss); + if ( rec->pos != pos-1 ) error("POS mismatch: %s\n", tsv->ss); + return 0; +} +static int tsv_setter_verify_ref_alt(tsv_t *tsv, bcf1_t *rec, void *usr) +{ + args_t *args = (args_t*) usr; + args->rev_als = 0; + char tmp = *tsv->se; *tsv->se = 0; + if ( strcmp(tsv->ss,rec->d.allele[0]) ) + { + if ( strcmp(tsv->ss,rec->d.allele[1]) ) { *tsv->se = tmp; error("REF/ALT mismatch: [%s][%s]\n", tsv->ss,rec->d.allele[1]); } + args->rev_als = 1; + } + *tsv->se = tmp; + while ( *tsv->se && isspace(*tsv->se) ) tsv->se++; + tsv->ss = tsv->se; + while ( *tsv->se && !isspace(*tsv->se) ) tsv->se++; + tmp = *tsv->se; *tsv->se = 0; + if ( !args->rev_als && strcmp(tsv->ss,rec->d.allele[1]) ) { *tsv->se = tmp; error("REF/ALT mismatch: [%s][%s]\n", tsv->ss,rec->d.allele[1]); } + else if ( args->rev_als && strcmp(tsv->ss,rec->d.allele[0]) ) { *tsv->se = tmp; error("REF/ALT mismatch: [%s][%s]\n", tsv->ss,rec->d.allele[0]); } + *tsv->se = tmp; + return 0; +} +static int tsv_setter_gt_gp(tsv_t *tsv, bcf1_t *rec, void *usr) +{ + args_t *args = (args_t*) usr; + int i, nsamples = bcf_hdr_nsamples(args->header); + for (i=0; iss, &tsv->se); + if ( tsv->ss==tsv->se ) { fprintf(stderr,"Could not parse first value of %d-th sample\n", i+1); return -1; } + tsv->ss = tsv->se+1; + ab = strtod(tsv->ss, &tsv->se); + if ( tsv->ss==tsv->se ) { fprintf(stderr,"Could not parse second value of %d-th sample\n", i+1); return -1; } + tsv->ss = tsv->se+1; + bb = strtod(tsv->ss, &tsv->se); + if ( tsv->ss==tsv->se ) { fprintf(stderr,"Could not parse third value of %d-th sample\n", i+1); return -1; } + tsv->ss = tsv->se+1; + + if ( args->rev_als ) { float tmp = bb; bb = aa; aa = tmp; } + args->flt[3*i+0] = aa; + args->flt[3*i+1] = ab; + args->flt[3*i+2] = bb; + + if ( aa >= ab ) + { + if ( aa >= bb ) args->gts[2*i+0] = args->gts[2*i+1] = bcf_gt_unphased(0); + else args->gts[2*i+0] = args->gts[2*i+1] = bcf_gt_unphased(1); + } + else if ( ab >= bb ) + { + args->gts[2*i+0] = bcf_gt_unphased(0); + args->gts[2*i+1] = bcf_gt_unphased(1); + } + else args->gts[2*i+0] = args->gts[2*i+1] = bcf_gt_unphased(1); + } + if ( *tsv->se ) error("Could not parse: %s\n", tsv->ss); + if ( bcf_update_genotypes(args->header,rec,args->gts,nsamples*2) ) error("Could not update GT field\n"); + if ( bcf_update_format_float(args->header,rec,"GP",args->flt,nsamples*3) ) error("Could not update GP field\n"); + return 0; +} +static int tsv_setter_haps(tsv_t *tsv, bcf1_t *rec, void *usr) +{ + args_t *args = (args_t*) usr; + int i, nsamples = bcf_hdr_nsamples(args->header); + + int32_t a0, a1; + if ( args->rev_als ) { a0 = bcf_gt_phased(1); a1 = bcf_gt_phased(0); } + else { a0 = bcf_gt_phased(0); a1 = bcf_gt_phased(1); } + + // up is short for "unphased" + int nup = 0; + for (i=0; iss + 4*i + nup; + int up = 0, all; + + for (all=0; all < 2; all++){ + // checking for premature ending + if ( !ss[0] || !ss[1] || !ss[2] || + (up && (!ss[3] || !ss[4]) ) ) + { + fprintf(stderr,"Wrong number of fields at %d-th sample ([%c][%c][%c]). ",i+1,ss[0],ss[1],ss[2]); + return -1; + } + + switch(ss[all*2+up]){ + case '0': + args->gts[2*i+all] = a0; + break; + case '1' : + args->gts[2*i+all] = a1; + break; + case '?' : + // there is no macro to express phased missing allele + args->gts[2*i+all] = bcf_gt_phased(-1); + break; + case '-' : + args->gts[2*i+all] = bcf_int32_vector_end; + break; + default : + fprintf(stderr,"Could not parse: [%c][%s]\n", ss[all*2+up],tsv->ss); + return -1; + } + if( ss[all*2+up+1]=='*' ) up = up + 1; + } + + if(up && up != 2) + { + fprintf(stderr,"Missing unphased marker '*': [%c][%s]", ss[2+up], tsv->ss); + return -1; + } + + // change alleles to unphased if the alleles are unphased + if ( up ) + { + args->gts[2*i] = bcf_gt_unphased(bcf_gt_allele(args->gts[2*i])); + args->gts[2*i+1] = bcf_gt_unphased(bcf_gt_allele(args->gts[2*i+1])); + } + nup = nup + up; + } + if ( tsv->ss[(nsamples-1)*4+3+nup] ) + { + fprintf(stderr,"nup: %d", nup); + fprintf(stderr,"Wrong number of fields (%d-th column = [%c]). ", nsamples*2,tsv->ss[(nsamples-1)*4+nup]); + return -1; + } + + if ( bcf_update_genotypes(args->header,rec,args->gts,nsamples*2) ) error("Could not update GT field\n"); + return 0; +} +static void gensample_to_vcf(args_t *args) +{ + /* + * Inpute: IMPUTE2 output (indentation changed here for clarity): + * + * 20:62116619_C_T 20:62116619 62116619 C T 0.969 0.031 0 ... + * --- 20:62116698_C_A 62116698 C A 1 0 0 ... + * + * Second column is expected in the form of CHROM:POS_REF_ALT. We use second + * column because the first can be empty ("--") when filling sites from reference + * panel. + * + * Output: VCF with filled GT,GP + * + */ + kstring_t line = {0,0,0}; + + char *gen_fname = NULL, *sample_fname = NULL; + sample_fname = strchr(args->infname,','); + if ( !sample_fname ) + { + args->str.l = 0; + ksprintf(&args->str,"%s.gen.gz", args->infname); + gen_fname = strdup(args->str.s); + args->str.l = 0; + ksprintf(&args->str,"%s.samples", args->infname); + sample_fname = strdup(args->str.s); + } + else + { + *sample_fname = 0; + gen_fname = strdup(args->infname); + sample_fname = strdup(sample_fname+1); + } + htsFile *gen_fh = hts_open(gen_fname, "r"); + if ( !gen_fh ) error("Could not read: %s\n", gen_fname); + if ( hts_getline(gen_fh, KS_SEP_LINE, &line) <= 0 ) error("Empty file: %s\n", gen_fname); + + // Find out the chromosome name, sample names, init and print the VCF header + args->str.l = 0; + char *ss, *se = line.s; + while ( *se && !isspace(*se) ) se++; + if ( !*se ) error("Could not parse %s: %s\n", gen_fname,line.s); + ss = se+1; + se = strchr(ss,':'); + if ( !se ) error("Expected CHROM:POS_REF_ALT in second column of %s\n", gen_fname); + kputsn(ss, se-ss, &args->str); + + tsv_t *tsv = tsv_init("-,CHROM_POS_REF_ALT,POS,REF_ALT,GT_GP"); + tsv_register(tsv, "CHROM_POS_REF_ALT", tsv_setter_chrom_pos_ref_alt, args); + tsv_register(tsv, "POS", tsv_setter_verify_pos, NULL); + tsv_register(tsv, "REF_ALT", tsv_setter_verify_ref_alt, args); + tsv_register(tsv, "GT_GP", tsv_setter_gt_gp, args); + + args->header = bcf_hdr_init("w"); + bcf_hdr_append(args->header, "##INFO="); + bcf_hdr_append(args->header, "##FORMAT="); + bcf_hdr_append(args->header, "##FORMAT="); + bcf_hdr_printf(args->header, "##contig=", args->str.s,0x7fffffff); // MAX_CSI_COOR + if (args->record_cmd_line) bcf_hdr_append_version(args->header, args->argc, args->argv, "bcftools_convert"); + + int i, nsamples; + char **samples = hts_readlist(sample_fname, 1, &nsamples); + if ( !samples ) error("Could not read %s\n", sample_fname); + for (i=2; iheader,samples[i]); + } + for (i=0; ioutfname,hts_bcf_wmode(args->output_type)); + if ( out_fh == NULL ) error("Can't write to \"%s\": %s\n", args->outfname, strerror(errno)); + if ( args->n_threads ) hts_set_threads(out_fh, args->n_threads); + bcf_hdr_write(out_fh,args->header); + bcf1_t *rec = bcf_init(); + + nsamples -= 2; + args->gts = (int32_t *) malloc(sizeof(int32_t)*nsamples*2); + args->flt = (float *) malloc(sizeof(float)*nsamples*3); + + do + { + bcf_clear(rec); + args->n.total++; + if ( !tsv_parse(tsv, rec, line.s) ) + bcf_write(out_fh, args->header, rec); + else + error("Error occurred while parsing: %s\n", line.s); + } + while ( hts_getline(gen_fh, KS_SEP_LINE, &line)>0 ); + + if ( hts_close(out_fh) ) error("Close failed: %s\n", args->outfname); + if ( hts_close(gen_fh) ) error("Close failed: %s\n", gen_fname); + bcf_hdr_destroy(args->header); + bcf_destroy(rec); + free(sample_fname); + free(gen_fname); + free(args->str.s); + free(line.s); + free(args->gts); + free(args->flt); + tsv_destroy(tsv); + + fprintf(stderr,"Number of processed rows: \t%d\n", args->n.total); +} + +static void haplegendsample_to_vcf(args_t *args) +{ + /* + * Convert from IMPUTE2 hap/legend/sample output files to VCF + * + * hap: + * 0 1 0 1 + * legend: + * id position a0 a1 + * 1:186946386_G_T 186946386 G T + * sample: + * sample population group sex + * sample1 sample1 sample1 2 + * sample2 sample2 sample2 2 + * + * Output: VCF with filled GT + */ + kstring_t line = {0,0,0}; + + char *hap_fname = NULL, *leg_fname = NULL, *sample_fname = NULL; + sample_fname = strchr(args->infname,','); + if ( !sample_fname ) + { + args->str.l = 0; + ksprintf(&args->str,"%s.hap.gz", args->infname); + hap_fname = strdup(args->str.s); + args->str.l = 0; + ksprintf(&args->str,"%s.samples", args->infname); + sample_fname = strdup(args->str.s); + args->str.l = 0; + ksprintf(&args->str,"%s.legend.gz", args->infname); + leg_fname = strdup(args->str.s); + } + else + { + char *ss = sample_fname, *se = strchr(ss+1,','); + if ( !se ) error("Could not parse hap/legend/sample file names: %s\n", args->infname); + *ss = 0; + *se = 0; + hap_fname = strdup(args->infname); + leg_fname = strdup(ss+1); + sample_fname = strdup(se+1); + } + htsFile *hap_fh = hts_open(hap_fname, "r"); + if ( !hap_fh ) error("Could not read: %s\n", hap_fname); + + htsFile *leg_fh = hts_open(leg_fname,"r"); + if ( !leg_fh ) error("Could not read: %s\n", leg_fname); + + // Eat up first legend line, then determine chromosome name + if ( hts_getline(leg_fh, KS_SEP_LINE, &line) <= 0 ) error("Empty file: %s\n", leg_fname); + if ( hts_getline(leg_fh, KS_SEP_LINE, &line) <= 0 ) error("Empty file: %s\n", leg_fname); + + // Find out the chromosome name, sample names, init and print the VCF header + args->str.l = 0; + char *se = strchr(line.s,':'); + if ( !se ) error("Expected CHROM:POS_REF_ALT in first column of %s\n", leg_fname); + kputsn(line.s, se-line.s, &args->str); + + tsv_t *leg_tsv = tsv_init("CHROM_POS_REF_ALT,POS,REF_ALT"); + tsv_register(leg_tsv, "CHROM_POS_REF_ALT", tsv_setter_chrom_pos_ref_alt, args); + tsv_register(leg_tsv, "POS", tsv_setter_verify_pos, NULL); + tsv_register(leg_tsv, "REF_ALT", tsv_setter_verify_ref_alt, args); + + tsv_t *hap_tsv = tsv_init("HAPS"); + tsv_register(hap_tsv, "HAPS", tsv_setter_haps, args); + + args->header = bcf_hdr_init("w"); + bcf_hdr_append(args->header, "##INFO="); + bcf_hdr_append(args->header, "##FORMAT="); + bcf_hdr_printf(args->header, "##contig=", args->str.s,0x7fffffff); // MAX_CSI_COOR + if (args->record_cmd_line) bcf_hdr_append_version(args->header, args->argc, args->argv, "bcftools_convert"); + + int i, nrows, nsamples; + char **samples = hts_readlist(sample_fname, 1, &nrows); + if ( !samples ) error("Could not read %s\n", sample_fname); + nsamples = nrows - 1; + + // sample_fname should contain a header line, so need to ignore first row + // returned from hts_readlist (i=1, and not i=0) + for (i=1; iheader,samples[i]); + } + bcf_hdr_add_sample(args->header,NULL); + for (i=0; ioutfname,hts_bcf_wmode(args->output_type)); + if ( out_fh == NULL ) error("Can't write to \"%s\": %s\n", args->outfname, strerror(errno)); + if ( args->n_threads ) hts_set_threads(out_fh, args->n_threads); + bcf_hdr_write(out_fh,args->header); + bcf1_t *rec = bcf_init(); + + args->gts = (int32_t *) malloc(sizeof(int32_t)*nsamples*2); + + while (1) + { + bcf_clear(rec); + args->n.total++; + if ( tsv_parse(leg_tsv, rec, line.s) ) + error("Error occurred while parsing %s: %s\n", leg_fname,line.s); + + if ( hts_getline(hap_fh, KS_SEP_LINE, &line)<=0 ) + error("Different number of records in %s and %s?\n", leg_fname,hap_fname); + + if ( tsv_parse(hap_tsv, rec, line.s) ) + error("Error occurred while parsing %s: %s\n", hap_fname,line.s); + + bcf_write(out_fh, args->header, rec); + + if ( hts_getline(leg_fh, KS_SEP_LINE, &line)<=0 ) + { + if ( hts_getline(hap_fh, KS_SEP_LINE, &line)>0 ) + error("Different number of records in %s and %s?\n", leg_fname,hap_fname); + break; + } + } + + if ( hts_close(out_fh) ) error("Close failed: %s\n", args->outfname); + if ( hts_close(hap_fh) ) error("Close failed: %s\n", hap_fname); + if ( hts_close(leg_fh) ) error("Close failed: %s\n", leg_fname); + bcf_hdr_destroy(args->header); + bcf_destroy(rec); + free(sample_fname); + free(hap_fname); + free(leg_fname); + free(args->str.s); + free(line.s); + free(args->gts); + tsv_destroy(hap_tsv); + tsv_destroy(leg_tsv); + + fprintf(stderr,"Number of processed rows: \t%d\n", args->n.total); +} + +static void hapsample_to_vcf(args_t *args) +{ + /* + * Input: SHAPEIT output + * + * 20:19995888_A_G 20:19995888 19995888 A G 0 0 0 0 ... + * + * First column is expected in the form of CHROM:POS_REF_ALT + * + * Output: VCF with filled GT + * + */ + kstring_t line = {0,0,0}; + + char *hap_fname = NULL, *sample_fname = NULL; + sample_fname = strchr(args->infname,','); + if ( !sample_fname ) + { + args->str.l = 0; + ksprintf(&args->str,"%s.hap.gz", args->infname); + hap_fname = strdup(args->str.s); + args->str.l = 0; + ksprintf(&args->str,"%s.samples", args->infname); + sample_fname = strdup(args->str.s); + } + else + { + *sample_fname = 0; + hap_fname = strdup(args->infname); + sample_fname = strdup(sample_fname+1); + } + htsFile *hap_fh = hts_open(hap_fname, "r"); + if ( !hap_fh ) error("Could not read: %s\n", hap_fname); + if ( hts_getline(hap_fh, KS_SEP_LINE, &line) <= 0 ) error("Empty file: %s\n", hap_fname); + + // Find out the chromosome name, sample names, init and print the VCF header + args->str.l = 0; + char *se = strchr(line.s,':'); + if ( !se ) error("Expected CHROM:POS_REF_ALT in first column of %s\n", hap_fname); + kputsn(line.s, se-line.s, &args->str); + + tsv_t *tsv = tsv_init("CHROM_POS_REF_ALT,-,POS,REF_ALT,HAPS"); + tsv_register(tsv, "CHROM_POS_REF_ALT", tsv_setter_chrom_pos_ref_alt, args); + tsv_register(tsv, "POS", tsv_setter_verify_pos, NULL); + tsv_register(tsv, "REF_ALT", tsv_setter_verify_ref_alt, args); + tsv_register(tsv, "HAPS", tsv_setter_haps, args); + + args->header = bcf_hdr_init("w"); + bcf_hdr_append(args->header, "##INFO="); + bcf_hdr_append(args->header, "##FORMAT="); + bcf_hdr_printf(args->header, "##contig=", args->str.s,0x7fffffff); // MAX_CSI_COOR + if (args->record_cmd_line) bcf_hdr_append_version(args->header, args->argc, args->argv, "bcftools_convert"); + + int i, nsamples; + char **samples = hts_readlist(sample_fname, 1, &nsamples); + if ( !samples ) error("Could not read %s\n", sample_fname); + for (i=2; iheader,samples[i]); + } + bcf_hdr_add_sample(args->header,NULL); + for (i=0; ioutfname,hts_bcf_wmode(args->output_type)); + if ( out_fh == NULL ) error("Can't write to \"%s\": %s\n", args->outfname, strerror(errno)); + if ( args->n_threads ) hts_set_threads(out_fh, args->n_threads); + bcf_hdr_write(out_fh,args->header); + bcf1_t *rec = bcf_init(); + + nsamples -= 2; + args->gts = (int32_t *) malloc(sizeof(int32_t)*nsamples*2); + + do + { + bcf_clear(rec); + args->n.total++; + if ( !tsv_parse(tsv, rec, line.s) ) + bcf_write(out_fh, args->header, rec); + else + error("Error occurred while parsing: %s\n", line.s); + } + while ( hts_getline(hap_fh, KS_SEP_LINE, &line)>0 ); + + if ( hts_close(out_fh) ) error("Close failed: %s\n", args->outfname); + if ( hts_close(hap_fh) ) error("Close failed: %s\n", hap_fname); + bcf_hdr_destroy(args->header); + bcf_destroy(rec); + free(sample_fname); + free(hap_fname); + free(args->str.s); + free(line.s); + free(args->gts); + tsv_destroy(tsv); + + fprintf(stderr,"Number of processed rows: \t%d\n", args->n.total); +} + +char *init_sample2sex(bcf_hdr_t *hdr, char *sex_fname) +{ + int i, nlines; + char *sample2sex = (char*) calloc(bcf_hdr_nsamples(hdr),1); + char **lines = hts_readlist(sex_fname, 1, &nlines); + if ( !lines ) error("Could not read %s\n", sex_fname); + for (i=0; ioutput_chrom_first_col) + kputs("%CHROM ", &str); + else + kputs("%CHROM:%POS\\_%REF\\_%FIRST_ALT ", &str); + + // insert rsid as second column if needed + if(args->output_vcf_ids) + kputs("%ID ", &str); + else + kputs("%CHROM:%POS\\_%REF\\_%FIRST_ALT ", &str); + + kputs("%POS %REF %FIRST_ALT", &str); + if ( !args->tag || !strcmp(args->tag,"GT") ) kputs("%_GT_TO_PROB3",&str); + else if ( !strcmp(args->tag,"PL") ) kputs("%_PL_TO_PROB3",&str); + else if ( !strcmp(args->tag,"GP") ) kputs("%_GP_TO_PROB3",&str); + else error("todo: --tag %s\n", args->tag); + kputs("\n", &str); + open_vcf(args,str.s); + + int ret, gen_compressed = 1, sample_compressed = 0; + char *gen_fname = NULL, *sample_fname = NULL; + str.l = 0; + kputs(args->outfname,&str); + int n_files = 0, i; + char **files = hts_readlist(str.s, 0, &n_files); + if ( n_files==1 ) + { + int l = str.l; + kputs(".samples",&str); + sample_fname = strdup(str.s); + str.l = l; + kputs(".gen.gz",&str); + gen_fname = strdup(str.s); + } + else if ( n_files==2 ) + { + if (strlen(files[0]) && strcmp(files[0],".")!=0) gen_fname = strdup(files[0]); + if (strlen(files[1]) && strcmp(files[1],".")!=0) sample_fname = strdup(files[1]); + } + else + { + error("Error parsing --gensample filenames: %s\n", args->outfname); + } + for (i=0; i3 && strcasecmp(".gz",sample_fname+strlen(sample_fname)-3)==0 ) sample_compressed = 0; + + if (gen_fname) fprintf(stderr, "Gen file: %s\n", gen_fname); + if (sample_fname) fprintf(stderr, "Sample file: %s\n", sample_fname); + + // write samples file + if (sample_fname) + { + char *sample2sex = NULL; + if ( args->sex_fname ) sample2sex = init_sample2sex(args->header,args->sex_fname); + + int i; + BGZF *sout = bgzf_open(sample_fname, sample_compressed ? "wg" : "wu"); + str.l = 0; + kputs(sample2sex ? "ID_1 ID_2 missing sex\n0 0 0 0\n" : "ID_1 ID_2 missing\n0 0 0\n", &str); + ret = bgzf_write(sout, str.s, str.l); + if ( ret != str.l ) error("Error writing %s: %s\n", sample_fname, strerror(errno)); + for (i=0; iheader); i++) + { + str.l = 0; + if ( sample2sex ) + ksprintf(&str, "%s %s 0 %c\n", args->header->samples[i],args->header->samples[i],sample2sex[i]); + else + ksprintf(&str, "%s %s 0\n", args->header->samples[i],args->header->samples[i]); + ret = bgzf_write(sout, str.s, str.l); + if ( ret != str.l ) error("Error writing %s: %s\n", sample_fname, strerror(errno)); + } + if ( bgzf_close(sout)!=0 ) error("Error closing %s: %s\n", sample_fname, strerror(errno)); + free(sample_fname); + free(sample2sex); + } + if (!gen_fname) { + if ( str.m ) free(str.s); + return; + } + + int prev_rid = -1, prev_pos = -1; + int no_alt = 0, non_biallelic = 0, filtered = 0, ndup = 0, nok = 0; + BGZF *gout = bgzf_open(gen_fname, gen_compressed ? "wg" : "wu"); + while ( bcf_sr_next_line(args->files) ) + { + bcf1_t *line = bcf_sr_get_line(args->files,0); + if ( args->filter ) + { + int pass = filter_test(args->filter, line, NULL); + if ( args->filter_logic & FLT_EXCLUDE ) pass = pass ? 0 : 1; + if ( !pass ) { filtered++; continue; } + } + + // ALT allele is required + if ( line->n_allele<2 ) { no_alt++; continue; } + + // biallelic required + if ( line->n_allele>2 ) { + if (!non_biallelic) + fprintf(stderr, "Warning: non-biallelic records are skipped. Consider splitting multi-allelic records into biallelic records using 'bcftools norm -m-'.\n"); + non_biallelic++; + continue; + } + + // skip duplicate lines, or otherwise shapeit complains + if ( prev_rid==line->rid && prev_pos==line->pos ) { ndup++; continue; } + prev_rid = line->rid; + prev_pos = line->pos; + + str.l = 0; + convert_line(args->convert, line, &str); + if ( str.l ) + { + int ret = bgzf_write(gout, str.s, str.l); + if ( ret!= str.l ) error("Error writing %s: %s\n", gen_fname,strerror(errno)); + nok++; + } + } + fprintf(stderr, "%d records written, %d skipped: %d/%d/%d/%d no-ALT/non-biallelic/filtered/duplicated\n", + nok, no_alt+non_biallelic+filtered+ndup, no_alt, non_biallelic, filtered, ndup); + + if ( str.m ) free(str.s); + if ( bgzf_close(gout)!=0 ) error("Error closing %s: %s\n", gen_fname,strerror(errno)); + free(gen_fname); +} + +static void vcf_to_haplegendsample(args_t *args) +{ + kstring_t str = {0,0,0}; + if ( args->hap2dip ) + kputs("%_GT_TO_HAP2\n", &str); + else + kputs("%_GT_TO_HAP\n", &str); + open_vcf(args,str.s); + + int ret, hap_compressed = 1, legend_compressed = 1, sample_compressed = 0; + char *hap_fname = NULL, *legend_fname = NULL, *sample_fname = NULL; + str.l = 0; + kputs(args->outfname,&str); + int n_files = 0, i; + char **files = hts_readlist(str.s, 0, &n_files); + if ( n_files==1 ) + { + int l = str.l; + kputs(".samples",&str); + sample_fname = strdup(str.s); + str.l = l; + kputs(".legend.gz",&str); + legend_fname = strdup(str.s); + str.l = l; + kputs(".hap.gz",&str); + hap_fname = strdup(str.s); + } + else if ( n_files==3 ) + { + if (strlen(files[0]) && strcmp(files[0],".")!=0) hap_fname = strdup(files[0]); + if (strlen(files[1]) && strcmp(files[1],".")!=0) legend_fname = strdup(files[1]); + if (strlen(files[2]) && strcmp(files[2],".")!=0) sample_fname = strdup(files[2]); + } + else + { + error("Error parsing --hapslegendsample filenames: %s\n", args->outfname); + } + for (i=0; i3 && strcasecmp(".gz",sample_fname+strlen(sample_fname)-3)==0 ) sample_compressed = 0; + + if (hap_fname) fprintf(stderr, "Haps file: %s\n", hap_fname); + if (legend_fname) fprintf(stderr, "Legend file: %s\n", legend_fname); + if (sample_fname) fprintf(stderr, "Sample file: %s\n", sample_fname); + + // write samples file + if (sample_fname) + { + char *sample2sex = NULL; + if ( args->sex_fname ) sample2sex = init_sample2sex(args->header,args->sex_fname); + + int i; + BGZF *sout = bgzf_open(sample_fname, sample_compressed ? "wg" : "wu"); + str.l = 0; + kputs("sample population group sex\n", &str); + ret = bgzf_write(sout, str.s, str.l); + if ( ret != str.l ) error("Error writing %s: %s\n", sample_fname, strerror(errno)); + for (i=0; iheader); i++) + { + str.l = 0; + ksprintf(&str, "%s %s %s %c\n", args->header->samples[i], args->header->samples[i], args->header->samples[i], sample2sex ? sample2sex[i] : '2'); + ret = bgzf_write(sout, str.s, str.l); + if ( ret != str.l ) error("Error writing %s: %s\n", sample_fname, strerror(errno)); + } + if ( bgzf_close(sout)!=0 ) error("Error closing %s: %s\n", sample_fname, strerror(errno)); + free(sample_fname); + free(sample2sex); + } + if (!hap_fname && !legend_fname) { + if ( str.m ) free(str.s); + return; + } + + // open haps and legend outputs + BGZF *hout = hap_fname ? bgzf_open(hap_fname, hap_compressed ? "wg" : "wu") : NULL; + if ( hap_compressed && args->n_threads ) bgzf_thread_pool(hout, args->files->p->pool, args->files->p->qsize); + BGZF *lout = legend_fname ? bgzf_open(legend_fname, legend_compressed ? "wg" : "wu") : NULL; + if (legend_fname) { + str.l = 0; + kputs("id position a0 a1\n", &str); + ret = bgzf_write(lout, str.s, str.l); + if ( ret != str.l ) error("Error writing %s: %s\n", legend_fname, strerror(errno)); + } + + int no_alt = 0, non_biallelic = 0, filtered = 0, nok = 0; + while ( bcf_sr_next_line(args->files) ) + { + bcf1_t *line = bcf_sr_get_line(args->files,0); + if ( args->filter ) + { + int pass = filter_test(args->filter, line, NULL); + if ( args->filter_logic & FLT_EXCLUDE ) pass = pass ? 0 : 1; + if ( !pass ) { filtered++; continue; } + } + + // ALT allele is required + if ( line->n_allele<2 ) { no_alt++; continue; } + // biallelic required + if ( line->n_allele>2 ) { + if (!non_biallelic) + fprintf(stderr, "Warning: non-biallelic records are skipped. Consider splitting multi-allelic records into biallelic records using 'bcftools norm -m-'.\n"); + non_biallelic++; + continue; + } + + str.l = 0; + convert_line(args->convert, line, &str); + if ( !str.l ) continue; + + // write haps file + if (hap_fname) { + ret = bgzf_write(hout, str.s, str.l); // write hap file + if ( ret != str.l ) error("Error writing %s: %s\n", hap_fname, strerror(errno)); + } + if (legend_fname) { + str.l = 0; + if ( args->output_vcf_ids && (line->d.id[0]!='.' || line->d.id[1]!=0) ) + ksprintf(&str, "%s %d %s %s\n", line->d.id, line->pos+1, line->d.allele[0], line->d.allele[1]); + else + ksprintf(&str, "%s:%d_%s_%s %d %s %s\n", bcf_seqname(args->header, line), line->pos+1, line->d.allele[0], line->d.allele[1], line->pos+1, line->d.allele[0], line->d.allele[1]); + + // write legend file + ret = bgzf_write(lout, str.s, str.l); + if ( ret != str.l ) error("Error writing %s: %s\n", legend_fname, strerror(errno)); + } + nok++; + } + fprintf(stderr, "%d records written, %d skipped: %d/%d/%d no-ALT/non-biallelic/filtered\n", nok,no_alt+non_biallelic+filtered, no_alt, non_biallelic, filtered); + if ( str.m ) free(str.s); + if ( hout && bgzf_close(hout)!=0 ) error("Error closing %s: %s\n", hap_fname, strerror(errno)); + if ( lout && bgzf_close(lout)!=0 ) error("Error closing %s: %s\n", legend_fname, strerror(errno)); + if (hap_fname) free(hap_fname); + if (legend_fname) free(legend_fname); +} + +static void vcf_to_hapsample(args_t *args) +{ + /* + * WTCCC style haplotypes file + * see https://mathgen.stats.ox.ac.uk/genetics_software/shapeit/shapeit.html#hapsample + * + * These are essentially the haplotypes from the impute2 format with some + * legend info tacked on to the first 5 columns + * + */ + kstring_t str = {0,0,0}; + + // print ID instead of CHROM:POS_REF_ALT1 + if ( args->output_vcf_ids ) + kputs("%CHROM %ID %POS %REF %FIRST_ALT ", &str); + else + kputs("%CHROM %CHROM:%POS\\_%REF\\_%FIRST_ALT %POS %REF %FIRST_ALT ", &str); + + if ( args->hap2dip ) + kputs("%_GT_TO_HAP2\n", &str); + else + kputs("%_GT_TO_HAP\n", &str); + open_vcf(args,str.s); + + int ret, hap_compressed = 1, sample_compressed = 0; + char *hap_fname = NULL, *sample_fname = NULL; + str.l = 0; + kputs(args->outfname,&str); + int n_files = 0, i; + char **files = hts_readlist(str.s, 0, &n_files); + if ( n_files==1 ) + { + int l = str.l; + kputs(".sample",&str); + sample_fname = strdup(str.s); + str.l = l; + kputs(".hap.gz",&str); + hap_fname = strdup(str.s); + } + else if ( n_files==2 ) + { + if (strlen(files[0]) && strcmp(files[0],".")!=0) hap_fname = strdup(files[0]); + if (strlen(files[1]) && strcmp(files[1],".")!=0) sample_fname = strdup(files[1]); + } + else + { + error("Error parsing --hapsample filenames: %s\n", args->outfname); + } + for (i=0; i3 && strcasecmp(".gz",sample_fname+strlen(sample_fname)-3)==0 ) sample_compressed = 0; + + if (hap_fname) fprintf(stderr, "Haps file: %s\n", hap_fname); + if (sample_fname) fprintf(stderr, "Sample file: %s\n", sample_fname); + + // write samples file + if (sample_fname) + { + char *sample2sex = NULL; + if ( args->sex_fname ) sample2sex = init_sample2sex(args->header,args->sex_fname); + + int i; + BGZF *sout = bgzf_open(sample_fname, sample_compressed ? "wg" : "wu"); + str.l = 0; + kputs(sample2sex ? "ID_1 ID_2 missing sex\n0 0 0 0\n" : "ID_1 ID_2 missing\n0 0 0\n", &str); + ret = bgzf_write(sout, str.s, str.l); + if ( ret != str.l ) error("Error writing %s: %s\n", sample_fname, strerror(errno)); + for (i=0; iheader); i++) + { + str.l = 0; + if ( sample2sex ) + ksprintf(&str, "%s %s 0 %c\n", args->header->samples[i],args->header->samples[i],sample2sex[i]); + else + ksprintf(&str, "%s %s 0\n", args->header->samples[i],args->header->samples[i]); + ret = bgzf_write(sout, str.s, str.l); + if ( ret != str.l ) error("Error writing %s: %s\n", sample_fname, strerror(errno)); + } + if ( bgzf_close(sout)!=0 ) error("Error closing %s: %s\n", sample_fname, strerror(errno)); + free(sample_fname); + free(sample2sex); + } + if (!hap_fname) { + if ( str.m ) free(str.s); + return; + } + + // open haps output + BGZF *hout = hap_fname ? bgzf_open(hap_fname, hap_compressed ? "wg" : "wu") : NULL; + if ( hap_compressed && args->n_threads ) bgzf_thread_pool(hout, args->files->p->pool, args->files->p->qsize); + + int no_alt = 0, non_biallelic = 0, filtered = 0, nok = 0; + while ( bcf_sr_next_line(args->files) ) + { + bcf1_t *line = bcf_sr_get_line(args->files,0); + if ( args->filter ) + { + int pass = filter_test(args->filter, line, NULL); + if ( args->filter_logic & FLT_EXCLUDE ) pass = pass ? 0 : 1; + if ( !pass ) { filtered++; continue; } + } + + // ALT allele is required + if ( line->n_allele<2 ) { no_alt++; continue; } + // biallelic required + if ( line->n_allele>2 ) { + if (!non_biallelic) + fprintf(stderr, "Warning: non-biallelic records are skipped. Consider splitting multi-allelic records into biallelic records using 'bcftools norm -m-'.\n"); + non_biallelic++; + continue; + } + + str.l = 0; + convert_line(args->convert, line, &str); + if ( !str.l ) continue; + + // write haps file + if (hap_fname) { + ret = bgzf_write(hout, str.s, str.l); // write hap file + if ( ret != str.l ) error("Error writing %s: %s\n", hap_fname, strerror(errno)); + } + nok++; + } + fprintf(stderr, "%d records written, %d skipped: %d/%d/%d no-ALT/non-biallelic/filtered\n", nok, no_alt+non_biallelic+filtered, no_alt, non_biallelic, filtered); + if ( str.m ) free(str.s); + if ( hout && bgzf_close(hout)!=0 ) error("Error closing %s: %s\n", hap_fname, strerror(errno)); + if (hap_fname) free(hap_fname); +} + +static void bcf_hdr_set_chrs(bcf_hdr_t *hdr, faidx_t *fai) +{ + int i, n = faidx_nseq(fai); + for (i=0; i", seq,len); + } +} +static inline int acgt_to_5(char base) +{ + if ( base=='A' ) return 0; + if ( base=='C' ) return 1; + if ( base=='G' ) return 2; + if ( base=='T' ) return 3; + return 4; +} +static inline int tsv_setter_aa1(args_t *args, char *ss, char *se, int alleles[], int *nals, int ref, int32_t *gts) +{ + if ( se - ss > 2 ) return -1; // currently only SNPs + + if ( ss[0]=='-' ) + { + // missing GT + gts[0] = bcf_gt_missing; + gts[1] = bcf_int32_vector_end; + args->n.missing++; + return 0; + } + if ( ss[0]=='I' ) return -2; // skip insertions/deletions for now + if ( ss[0]=='D' ) return -2; + + int a0 = acgt_to_5(toupper(ss[0])); + int a1 = ss[1] ? acgt_to_5(toupper(ss[1])) : a0; + if ( alleles[a0]<0 ) alleles[a0] = (*nals)++; + if ( alleles[a1]<0 ) alleles[a1] = (*nals)++; + + gts[0] = bcf_gt_unphased(alleles[a0]); + gts[1] = ss[1] ? bcf_gt_unphased(alleles[a1]) : bcf_int32_vector_end; + + if ( ref==a0 && ref==a1 ) args->n.hom_rr++; // hom ref: RR + else if ( ref==a0 ) args->n.het_ra++; // het: RA + else if ( ref==a1 ) args->n.het_ra++; // het: AR + else if ( a0==a1 ) args->n.hom_aa++; // hom-alt: AA + else args->n.het_aa++; // non-ref het: AA + + return 0; +} +static int tsv_setter_aa(tsv_t *tsv, bcf1_t *rec, void *usr) +{ + args_t *args = (args_t*) usr; + + int len; + char *ref = faidx_fetch_seq(args->ref, (char*)bcf_hdr_id2name(args->header,rec->rid), rec->pos, rec->pos, &len); + if ( !ref ) error("faidx_fetch_seq failed at %s:%d\n", bcf_hdr_id2name(args->header,rec->rid), rec->pos+1); + + int nals = 1, alleles[5] = { -1, -1, -1, -1, -1 }; // a,c,g,t,n + ref[0] = toupper(ref[0]); + int iref = acgt_to_5(ref[0]); + alleles[iref] = 0; + + rec->n_sample = bcf_hdr_nsamples(args->header); + + int i, ret; + for (i=0; in_sample; i++) + { + if ( i>0 ) + { + ret = tsv_next(tsv); + if ( ret==-1 ) error("Too few columns for %d samples at %s:%d\n", rec->n_sample,bcf_hdr_id2name(args->header,rec->rid), rec->pos+1); + } + ret = tsv_setter_aa1(args, tsv->ss, tsv->se, alleles, &nals, iref, args->gts+i*2); + if ( ret==-1 ) error("Error parsing the site %s:%d, expected two characters\n", bcf_hdr_id2name(args->header,rec->rid), rec->pos+1); + if ( ret==-2 ) + { + // something else than a SNP + free(ref); + return -1; + } + } + + args->str.l = 0; + kputc(ref[0], &args->str); + for (i=0; i<5; i++) + { + if ( alleles[i]>0 ) + { + kputc(',', &args->str); + kputc("ACGTN"[i], &args->str); + } + } + bcf_update_alleles_str(args->header, rec, args->str.s); + if ( bcf_update_genotypes(args->header,rec,args->gts,rec->n_sample*2) ) error("Could not update the GT field\n"); + + free(ref); + return 0; +} + +static void tsv_to_vcf(args_t *args) +{ + if ( !args->ref_fname ) error("--tsv2vcf requires the --fasta-ref option\n"); + if ( !args->sample_list ) error("--tsv2vcf requires the --samples option\n"); + + args->ref = fai_load(args->ref_fname); + if ( !args->ref ) error("Could not load the reference %s\n", args->ref_fname); + + args->header = bcf_hdr_init("w"); + bcf_hdr_set_chrs(args->header, args->ref); + bcf_hdr_append(args->header, "##FORMAT="); + if (args->record_cmd_line) bcf_hdr_append_version(args->header, args->argc, args->argv, "bcftools_convert"); + + int i, n; + char **smpls = hts_readlist(args->sample_list, args->sample_is_file, &n); + if ( !smpls ) error("Could not parse %s\n", args->sample_list); + for (i=0; iheader, smpls[i]); + free(smpls[i]); + } + free(smpls); + bcf_hdr_add_sample(args->header, NULL); + args->gts = (int32_t *) malloc(sizeof(int32_t)*n*2); + + htsFile *out_fh = hts_open(args->outfname,hts_bcf_wmode(args->output_type)); + if ( out_fh == NULL ) error("Can't write to \"%s\": %s\n", args->outfname, strerror(errno)); + if ( args->n_threads ) hts_set_threads(out_fh, args->n_threads); + bcf_hdr_write(out_fh,args->header); + + tsv_t *tsv = tsv_init(args->columns ? args->columns : "ID,CHROM,POS,AA"); + if ( tsv_register(tsv, "CHROM", tsv_setter_chrom, args->header) < 0 ) error("Expected CHROM column\n"); + if ( tsv_register(tsv, "POS", tsv_setter_pos, NULL) < 0 ) error("Expected POS column\n"); + if ( tsv_register(tsv, "ID", tsv_setter_id, args->header) < 0 && !args->columns ) error("Expected ID column\n"); + if ( tsv_register(tsv, "AA", tsv_setter_aa, args) < 0 ) error("Expected AA column\n"); + + bcf1_t *rec = bcf_init(); + bcf_float_set_missing(rec->qual); + + kstring_t line = {0,0,0}; + htsFile *in_fh = hts_open(args->infname, "r"); + if ( !in_fh ) error("Could not read: %s\n", args->infname); + while ( hts_getline(in_fh, KS_SEP_LINE, &line) > 0 ) + { + if ( line.s[0]=='#' ) continue; // skip comments + bcf_clear(rec); + + args->n.total++; + if ( !tsv_parse(tsv, rec, line.s) ) + bcf_write(out_fh, args->header, rec); + else + args->n.skipped++; + } + if ( hts_close(in_fh) ) error("Close failed: %s\n", args->infname); + free(line.s); + + bcf_hdr_destroy(args->header); + hts_close(out_fh); + tsv_destroy(tsv); + bcf_destroy(rec); + free(args->str.s); + free(args->gts); + + fprintf(stderr,"Rows total: \t%d\n", args->n.total); + fprintf(stderr,"Rows skipped: \t%d\n", args->n.skipped); + fprintf(stderr,"Missing GTs: \t%d\n", args->n.missing); + fprintf(stderr,"Hom RR: \t%d\n", args->n.hom_rr); + fprintf(stderr,"Het RA: \t%d\n", args->n.het_ra); + fprintf(stderr,"Hom AA: \t%d\n", args->n.hom_aa); + fprintf(stderr,"Het AA: \t%d\n", args->n.het_aa); +} + +static void vcf_to_vcf(args_t *args) +{ + open_vcf(args,NULL); + htsFile *out_fh = hts_open(args->outfname,hts_bcf_wmode(args->output_type)); + if ( out_fh == NULL ) error("Can't write to \"%s\": %s\n", args->outfname, strerror(errno)); + if ( args->n_threads ) hts_set_threads(out_fh, args->n_threads); + + bcf_hdr_t *hdr = bcf_sr_get_header(args->files,0); + bcf_hdr_write(out_fh,hdr); + + while ( bcf_sr_next_line(args->files) ) + { + bcf1_t *line = bcf_sr_get_line(args->files,0); + if ( args->filter ) + { + int pass = filter_test(args->filter, line, NULL); + if ( args->filter_logic & FLT_EXCLUDE ) pass = pass ? 0 : 1; + if ( !pass ) continue; + } + bcf_write(out_fh,hdr,line); + } + hts_close(out_fh); +} + +static void gvcf_to_vcf(args_t *args) +{ + if ( !args->ref_fname ) error("--gvcf2vcf requires the --fasta-ref option\n"); + + args->ref = fai_load(args->ref_fname); + if ( !args->ref ) error("Could not load the fai index for reference %s\n", args->ref_fname); + + open_vcf(args,NULL); + htsFile *out_fh = hts_open(args->outfname,hts_bcf_wmode(args->output_type)); + if ( out_fh == NULL ) error("Can't write to \"%s\": %s\n", args->outfname, strerror(errno)); + if ( args->n_threads ) hts_set_threads(out_fh, args->n_threads); + + bcf_hdr_t *hdr = bcf_sr_get_header(args->files,0); + if (args->record_cmd_line) bcf_hdr_append_version(hdr, args->argc, args->argv, "bcftools_convert"); + bcf_hdr_write(out_fh,hdr); + + int32_t *itmp = NULL, nitmp = 0; + + while ( bcf_sr_next_line(args->files) ) + { + bcf1_t *line = bcf_sr_get_line(args->files,0); + if ( args->filter ) + { + int pass = filter_test(args->filter, line, NULL); + if ( args->filter_logic & FLT_EXCLUDE ) pass = pass ? 0 : 1; + if ( !pass ) continue; + } + + if (!bcf_has_filter(hdr,line,"PASS")) + { + bcf_write(out_fh,hdr,line); + continue; + } + + // check if alleles compatible with being a gVCF record + int i, gallele = -1; + if (line->n_allele==1) + gallele = 0; // illumina/bcftools-call gvcf (if INFO/END present) + else + { + if ( line->d.allele[1][0]!='<' ) continue; + for (i=1; in_allele; i++) + { + if ( line->d.allele[i][1]=='*' && line->d.allele[i][2]=='>' && line->d.allele[i][3]=='\0' ) { gallele = i; break; } // mpileup/spec compliant gVCF + if ( line->d.allele[i][1]=='X' && line->d.allele[i][2]=='>' && line->d.allele[i][3]=='\0' ) { gallele = i; break; } // old mpileup gVCF + if ( strcmp(line->d.allele[i],"")==0 ) { gallele = i; break; } // GATK gVCF + } + } + + // no gVCF compatible alleles + if (gallele<0) + { + bcf_write(out_fh,hdr,line); + continue; + } + + int nend = bcf_get_info_int32(hdr,line,"END",&itmp,&nitmp); + if ( nend!=1 ) + { + // No INFO/END => not gVCF record + bcf_write(out_fh,hdr,line); + continue; + } + bcf_update_info_int32(hdr,line,"END",NULL,0); + int pos, len; + for (pos=line->pos; pospos = pos; + char *ref = faidx_fetch_seq(args->ref, (char*)bcf_hdr_id2name(hdr,line->rid), line->pos, line->pos, &len); + if ( !ref ) error("faidx_fetch_seq failed at %s:%d\n", bcf_hdr_id2name(hdr,line->rid), line->pos+1); + strncpy(line->d.allele[0],ref,len); + bcf_write(out_fh,hdr,line); + free(ref); + } + } + free(itmp); + hts_close(out_fh); +} + +static void usage(void) +{ + fprintf(stderr, "\n"); + fprintf(stderr, "About: Converts VCF/BCF to other formats and back. See man page for file\n"); + fprintf(stderr, " formats details. When specifying output files explicitly instead\n"); + fprintf(stderr, " of with , one can use '-' for stdout and '.' to suppress.\n"); + fprintf(stderr, "Usage: bcftools convert [OPTIONS] \n"); + fprintf(stderr, "\n"); + fprintf(stderr, "VCF input options:\n"); + fprintf(stderr, " -e, --exclude exclude sites for which the expression is true\n"); + fprintf(stderr, " -i, --include select sites for which the expression is true\n"); + fprintf(stderr, " -r, --regions restrict to comma-separated list of regions\n"); + fprintf(stderr, " -R, --regions-file restrict to regions listed in a file\n"); + fprintf(stderr, " -s, --samples list of samples to include\n"); + fprintf(stderr, " -S, --samples-file file of samples to include\n"); + fprintf(stderr, " -t, --targets similar to -r but streams rather than index-jumps\n"); + fprintf(stderr, " -T, --targets-file similar to -R but streams rather than index-jumps\n"); + fprintf(stderr, "\n"); + fprintf(stderr, "VCF output options:\n"); + fprintf(stderr, " --no-version do not append version and command line to the header\n"); + fprintf(stderr, " -o, --output output file name [stdout]\n"); + fprintf(stderr, " -O, --output-type b: compressed BCF, u: uncompressed BCF, z: compressed VCF, v: uncompressed VCF [v]\n"); + fprintf(stderr, " --threads number of extra output compression threads [0]\n"); + fprintf(stderr, "\n"); + fprintf(stderr, "GEN/SAMPLE conversion (input/output from IMPUTE2):\n"); + fprintf(stderr, " -G, --gensample2vcf <...> |,\n"); + fprintf(stderr, " -g, --gensample <...> |,\n"); + fprintf(stderr, " --tag tag to take values for .gen file: GT,PL,GL,GP [GT]\n"); + fprintf(stderr, " --chrom output chromosome in first column instead of CHROM:POS_REF_ALT\n"); + fprintf(stderr, " --sex output sex column in the sample-file, input format is: Sample\\t[MF]\n"); + fprintf(stderr, " --vcf-ids output VCF IDs in second column instead of CHROM:POS_REF_ALT\n"); + fprintf(stderr, "\n"); + fprintf(stderr, "gVCF conversion:\n"); + fprintf(stderr, " --gvcf2vcf expand gVCF reference blocks\n"); + fprintf(stderr, " -f, --fasta-ref reference sequence in fasta format\n"); + fprintf(stderr, "\n"); + fprintf(stderr, "HAP/SAMPLE conversion (output from SHAPEIT):\n"); + fprintf(stderr, " --hapsample2vcf <...> |,\n"); + fprintf(stderr, " --hapsample <...> |,\n"); + fprintf(stderr, " --haploid2diploid convert haploid genotypes to diploid homozygotes\n"); + fprintf(stderr, " --sex output sex column in the sample-file, input format is: Sample\\t[MF]\n"); + fprintf(stderr, " --vcf-ids output VCF IDs instead of CHROM:POS_REF_ALT\n"); + fprintf(stderr, "\n"); + fprintf(stderr, "HAP/LEGEND/SAMPLE conversion:\n"); + fprintf(stderr, " -H, --haplegendsample2vcf <...> |,,\n"); + fprintf(stderr, " -h, --haplegendsample <...> |,,\n"); + fprintf(stderr, " --haploid2diploid convert haploid genotypes to diploid homozygotes\n"); + fprintf(stderr, " --sex output sex column in the sample-file, input format is: Sample\\t[MF]\n"); + fprintf(stderr, " --vcf-ids output VCF IDs instead of CHROM:POS_REF_ALT\n"); + fprintf(stderr, "\n"); + fprintf(stderr, "TSV conversion:\n"); + fprintf(stderr, " --tsv2vcf \n"); + fprintf(stderr, " -c, --columns columns of the input tsv file [ID,CHROM,POS,AA]\n"); + fprintf(stderr, " -f, --fasta-ref reference sequence in fasta format\n"); + fprintf(stderr, " -s, --samples list of sample names\n"); + fprintf(stderr, " -S, --samples-file file of sample names\n"); + fprintf(stderr, "\n"); + // fprintf(stderr, "PLINK options:\n"); + // fprintf(stderr, " -p, --plink |,,|,,|,\n"); + // fprintf(stderr, " --tped make tped file instead\n"); + // fprintf(stderr, " --bin make binary bed/fam/bim files\n"); + // fprintf(stderr, "\n"); + // fprintf(stderr, "PBWT options:\n"); + // fprintf(stderr, " -b, --pbwt or ,,,\n"); + // fprintf(stderr, "\n"); + exit(1); +} + +int main_vcfconvert(int argc, char *argv[]) +{ + int c; + args_t *args = (args_t*) calloc(1,sizeof(args_t)); + args->argc = argc; args->argv = argv; + args->outfname = "-"; + args->output_type = FT_VCF; + args->n_threads = 0; + args->record_cmd_line = 1; + + static struct option loptions[] = + { + {"include",required_argument,NULL,'i'}, + {"exclude",required_argument,NULL,'e'}, + {"output",required_argument,NULL,'o'}, + {"output-type",required_argument,NULL,'O'}, + {"threads",required_argument,NULL,9}, + {"regions",required_argument,NULL,'r'}, + {"regions-file",required_argument,NULL,'R'}, + {"targets",required_argument,NULL,'t'}, + {"targets-file",required_argument,NULL,'T'}, + {"samples",required_argument,NULL,'s'}, + {"samples-file",required_argument,NULL,'S'}, + {"sex",required_argument,NULL,11}, + {"gensample",required_argument,NULL,'g'}, + {"gensample2vcf",required_argument,NULL,'G'}, + {"tag",required_argument,NULL,1}, + {"chrom",no_argument,NULL,8}, + {"tsv2vcf",required_argument,NULL,2}, + {"hapsample",required_argument,NULL,7}, + {"hapsample2vcf",required_argument,NULL,3}, + {"vcf-ids",no_argument,NULL,4}, + {"haploid2diploid",no_argument,NULL,5}, + {"gvcf2vcf",no_argument,NULL,6}, + {"haplegendsample",required_argument,NULL,'h'}, + {"haplegendsample2vcf",required_argument,NULL,'H'}, + {"columns",required_argument,NULL,'c'}, + {"fasta-ref",required_argument,NULL,'f'}, + {"no-version",no_argument,NULL,10}, + {NULL,0,NULL,0} + }; + while ((c = getopt_long(argc, argv, "?h:r:R:s:S:t:T:i:e:g:G:o:O:c:f:H:",loptions,NULL)) >= 0) { + switch (c) { + case 'e': args->filter_str = optarg; args->filter_logic |= FLT_EXCLUDE; break; + case 'i': args->filter_str = optarg; args->filter_logic |= FLT_INCLUDE; break; + case 'r': args->regions_list = optarg; break; + case 'R': args->regions_list = optarg; args->regions_is_file = 1; break; + case 't': args->targets_list = optarg; break; + case 'T': args->targets_list = optarg; args->targets_is_file = 1; break; + case 's': args->sample_list = optarg; break; + case 'S': args->sample_list = optarg; args->sample_is_file = 1; break; + case 'g': args->convert_func = vcf_to_gensample; args->outfname = optarg; break; + case 'G': args->convert_func = gensample_to_vcf; args->infname = optarg; break; + case 1 : args->tag = optarg; break; + case 2 : args->convert_func = tsv_to_vcf; args->infname = optarg; break; + case 3 : args->convert_func = hapsample_to_vcf; args->infname = optarg; break; + case 4 : args->output_vcf_ids = 1; break; + case 5 : args->hap2dip = 1; break; + case 6 : args->convert_func = gvcf_to_vcf; break; + case 7 : args->convert_func = vcf_to_hapsample; args->outfname = optarg; break; + case 8 : args->output_chrom_first_col = 1; break; + case 'H': args->convert_func = haplegendsample_to_vcf; args->infname = optarg; break; + case 'f': args->ref_fname = optarg; break; + case 'c': args->columns = optarg; break; + case 'o': args->outfname = optarg; break; + case 'O': + switch (optarg[0]) { + case 'b': args->output_type = FT_BCF_GZ; break; + case 'u': args->output_type = FT_BCF; break; + case 'z': args->output_type = FT_VCF_GZ; break; + case 'v': args->output_type = FT_VCF; break; + default: error("The output type \"%s\" not recognised\n", optarg); + } + break; + case 'h': args->convert_func = vcf_to_haplegendsample; args->outfname = optarg; break; + case 9 : args->n_threads = strtol(optarg, 0, 0); break; + case 10 : args->record_cmd_line = 0; break; + case 11 : args->sex_fname = optarg; break; + case '?': usage(); + default: error("Unknown argument: %s\n", optarg); + } + } + + if ( !args->infname ) + { + if ( optind>=argc ) + { + if ( !isatty(fileno((FILE *)stdin)) ) args->infname = "-"; + } + else args->infname = argv[optind]; + } + if ( !args->infname ) usage(); + + if ( args->convert_func ) args->convert_func(args); + else vcf_to_vcf(args); + + destroy_data(args); + free(args); + return 0; +} diff --git a/vcffilter.c b/vcffilter.c new file mode 100644 index 0000000..c1b41f2 --- /dev/null +++ b/vcffilter.c @@ -0,0 +1,573 @@ +/* vcffilter.c -- Apply fixed-threshold filters. + + Copyright (C) 2013-2014 Genome Research Ltd. + + Author: Petr Danecek + +Permission is hereby granted, free of charge, to any person obtaining a copy +of this software and associated documentation files (the "Software"), to deal +in the Software without restriction, including without limitation the rights +to use, copy, modify, merge, publish, distribute, sublicense, and/or sell +copies of the Software, and to permit persons to whom the Software is +furnished to do so, subject to the following conditions: + +The above copyright notice and this permission notice shall be included in +all copies or substantial portions of the Software. + +THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE +AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER +LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, +OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN +THE SOFTWARE. */ + +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include "bcftools.h" +#include "filter.h" +#include "rbuf.h" + +// Logic of the filters: include or exclude sites which match the filters? +#define FLT_INCLUDE 1 +#define FLT_EXCLUDE 2 + +// FILTER columns annotation: replace or add to existing FILTERs; set FILTER to PASS at good sites? +#define ANNOT_ADD 1 +#define ANNOT_RESET 2 + +// Set genotypes of filtered samples +#define SET_GTS_MISSING 1 +#define SET_GTS_REF 2 + +typedef struct _args_t +{ + filter_t *filter; + char *filter_str; + int filter_logic; // include or exclude sites which match the filters? One of FLT_INCLUDE/FLT_EXCLUDE + const uint8_t *smpl_pass; + int set_gts; + char *soft_filter; // drop failed sites or annotate FILTER column? + int annot_mode; // add to existing FILTER annotation or replace? Otherwise reset FILTER to PASS or leave as it is? + int flt_fail, flt_pass; // BCF ids of fail and pass filters + int snp_gap, indel_gap, IndelGap_id, SnpGap_id; + int32_t ntmpi, *tmpi, ntmp_ac, *tmp_ac; + rbuf_t rbuf; + bcf1_t **rbuf_lines; + + bcf_srs_t *files; + bcf_hdr_t *hdr; + htsFile *out_fh; + int output_type, n_threads; + + char **argv, *output_fname, *targets_list, *regions_list; + int argc, record_cmd_line; +} +args_t; + +static void init_data(args_t *args) +{ + args->out_fh = hts_open(args->output_fname,hts_bcf_wmode(args->output_type)); + if ( args->out_fh == NULL ) error("Can't write to \"%s\": %s\n", args->output_fname, strerror(errno)); + if ( args->n_threads ) hts_set_threads(args->out_fh, args->n_threads); + + args->hdr = args->files->readers[0].header; + args->flt_pass = bcf_hdr_id2int(args->hdr,BCF_DT_ID,"PASS"); assert( !args->flt_pass ); // sanity check: required by BCF spec + + // -i or -e: append FILTER line + if ( args->soft_filter && args->filter_logic ) + { + kstring_t flt_name = {0,0,0}; + if ( strcmp(args->soft_filter,"+") ) + kputs(args->soft_filter, &flt_name); + else + { + // Make up a filter name + int i = 0, id = -1; + do + { + ksprintf(&flt_name,"Filter%d", ++i); + id = bcf_hdr_id2int(args->hdr,BCF_DT_ID,flt_name.s); + } + while ( bcf_hdr_idinfo_exists(args->hdr,BCF_HL_FLT,id) ); + } + // escape quotes + kstring_t tmp = {0,0,0}; + char *t = args->filter_str; + while ( *t ) + { + if ( *t=='"' ) kputc('\\',&tmp); + kputc(*t,&tmp); + t++; + } + int ret = bcf_hdr_printf(args->hdr, "##FILTER=", flt_name.s,args->filter_logic & FLT_INCLUDE ? "not true" : "true", tmp.s); + if ( ret!=0 ) + error("Failed to append header line: ##FILTER=\n", flt_name.s,args->filter_logic & FLT_INCLUDE ? "not true" : "true", tmp.s); + args->flt_fail = bcf_hdr_id2int(args->hdr,BCF_DT_ID,flt_name.s); assert( args->flt_fail>=0 ); + free(flt_name.s); + free(tmp.s); + } + + if ( args->snp_gap || args->indel_gap ) + { + if ( !args->filter_logic && args->soft_filter && strcmp(args->soft_filter,"+") ) + { + kstring_t tmp = {0,0,0}; + if ( args->snp_gap ) kputs("\"SnpGap\"", &tmp); + if ( args->indel_gap ) + { + if ( tmp.s ) kputs(" and ", &tmp); + kputs("\"IndelGap\"", &tmp); + } + if ( strncmp(tmp.s+1,args->soft_filter,tmp.l-2) ) + fprintf(stderr,"Warning: using %s filter name instead of \"%s\"\n", tmp.s,args->soft_filter); + free(tmp.s); + } + + rbuf_init(&args->rbuf, 64); + args->rbuf_lines = (bcf1_t**) calloc(args->rbuf.m, sizeof(bcf1_t*)); + if ( args->snp_gap ) + { + bcf_hdr_printf(args->hdr, "##FILTER=", args->snp_gap); + args->SnpGap_id = bcf_hdr_id2int(args->hdr, BCF_DT_ID, "SnpGap"); + assert( args->SnpGap_id>=0 ); + } + if ( args->indel_gap ) + { + bcf_hdr_printf(args->hdr, "##FILTER=", args->indel_gap); + args->IndelGap_id = bcf_hdr_id2int(args->hdr, BCF_DT_ID, "IndelGap"); + assert( args->IndelGap_id>=0 ); + } + } + + if (args->record_cmd_line) bcf_hdr_append_version(args->hdr, args->argc, args->argv, "bcftools_filter"); + + if ( args->filter_str ) + args->filter = filter_init(args->hdr, args->filter_str); +} + +static void destroy_data(args_t *args) +{ + if ( args->rbuf_lines ) + { + int i; + for (i=0; irbuf.m; i++) + if ( args->rbuf_lines[i] ) bcf_destroy1(args->rbuf_lines[i]); + free(args->rbuf_lines); + } + if ( args->filter ) + filter_destroy(args->filter); + free(args->tmpi); + free(args->tmp_ac); +} + +static void flush_buffer(args_t *args, int n) +{ + int i, j; + for (i=0; irbuf); + bcf1_t *rec = args->rbuf_lines[k]; + + int pass = 1; + if ( !args->soft_filter ) + { + for (j=0; jd.n_flt; j++) + { + if ( args->indel_gap && rec->d.flt[j]==args->IndelGap_id ) { pass = 0; break; } + if ( args->snp_gap && rec->d.flt[j]==args->SnpGap_id ) { pass = 0; break; } + } + } + if ( pass ) bcf_write1(args->out_fh, args->hdr, rec); + } +} + +#define SWAP(type_t, a, b) { type_t t = a; a = b; b = t; } +static void buffered_filters(args_t *args, bcf1_t *line) +{ + /** + * The logic of SnpGap=3. The SNPs at positions 1 and 7 are filtered, + * positions 0 and 8 are not: + * 0123456789 + * ref .G.GT..G.. + * del .A.G-..A.. + * Here the positions 1 and 6 are filtered, 0 and 7 are not: + * 0123-456789 + * ref .G.G-..G.. + * ins .A.GT..A.. + * + * The logic of IndelGap=2. The second indel is filtered: + * 012345678901 + * ref .GT.GT..GT.. + * del .G-.G-..G-.. + * And similarly here, the second is filtered: + * 01 23 456 78 + * ref .A-.A-..A-.. + * ins .AT.AT..AT.. + */ + + // To avoid additional data structure, we abuse bcf1_t's var and var_type records. + const int SnpGap_set = VCF_OTHER<<1; + const int IndelGap_set = VCF_OTHER<<2; + const int IndelGap_flush = VCF_OTHER<<3; + + int var_type = 0, i; + if ( line ) + { + // Still on the same chromosome? + int ilast = rbuf_last(&args->rbuf); + if ( ilast>=0 && line->rid != args->rbuf_lines[ilast]->rid ) + flush_buffer(args, args->rbuf.n); // new chromosome, flush everything + + rbuf_expand0(&args->rbuf,bcf1_t*,args->rbuf.n,args->rbuf_lines); + + // Insert the new record in the buffer. The line would be overwritten in + // the next bcf_sr_next_line call, therefore we need to swap it with an + // unused one + ilast = rbuf_append(&args->rbuf); + if ( !args->rbuf_lines[ilast] ) args->rbuf_lines[ilast] = bcf_init1(); + SWAP(bcf1_t*, args->files->readers[0].buffer[0], args->rbuf_lines[ilast]); + + var_type = bcf_get_variant_types(line); + + // Find out the size of an indel. The indel boundaries are based on REF + // (POS+1,POS+rlen-1). This is not entirely correct: mpileup likes to + // output REF=CAGAGAGAGA, ALT=CAGAGAGAGAGA where REF=C,ALT=CGA could be + // used. This filter is therefore more strict and may remove some valid + // SNPs. + int len = 1; + if ( var_type & VCF_INDEL ) + { + for (i=1; in_allele; i++) + if ( len < 1-line->d.var[i].n ) len = 1-line->d.var[i].n; + } + + // Set the REF allele's length to max deletion length or to 1 if a SNP or an insertion. + line->d.var[0].n = len; + } + + int k_flush = 1; + if ( args->indel_gap ) + { + k_flush = 0; + // Find indels which are too close to each other + int last_to = -1; + for (i=-1; rbuf_next(&args->rbuf,&i); ) + { + bcf1_t *rec = args->rbuf_lines[i]; + int rec_from = rec->pos; + if ( last_to!=-1 && last_to < rec_from ) break; + + k_flush++; + if ( !(rec->d.var_type & VCF_INDEL) ) continue; + + rec->d.var_type |= IndelGap_set; + last_to = args->indel_gap + rec->pos + rec->d.var[0].n - 1; + } + if ( i==args->rbuf.f && line && last_to!=-1 ) k_flush = 0; + if ( k_flush || !line ) + { + // Select the best indel from the cluster of k_flush indels + int k = 0, max_ac = -1, imax_ac = -1; + for (i=-1; rbuf_next(&args->rbuf,&i) && krbuf_lines[i]; + if ( !(rec->d.var_type & IndelGap_set) ) continue; + hts_expand(int, rec->n_allele, args->ntmpi, args->tmpi); + int ret = bcf_calc_ac(args->hdr, rec, args->tmpi, BCF_UN_ALL); + if ( imax_ac==-1 || (ret && max_ac < args->tmpi[1]) ) { max_ac = args->tmpi[1]; imax_ac = i; } + } + + // Filter all but the best indel (with max AF or first if AF not available) + k = 0; + for (i=-1; rbuf_next(&args->rbuf,&i) && krbuf_lines[i]; + if ( !(rec->d.var_type & IndelGap_set) ) continue; + rec->d.var_type |= IndelGap_flush; + if ( i!=imax_ac ) bcf_add_filter(args->hdr, args->rbuf_lines[i], args->IndelGap_id); + } + } + } + + if ( !line ) + { + // Finished: flush everything + flush_buffer(args, args->rbuf.n); + return; + } + + int j_flush = 1; + if ( args->snp_gap ) + { + j_flush = 0; + int last_from = line->pos; + for (i=-1; rbuf_next(&args->rbuf,&i); ) + { + bcf1_t *rec = args->rbuf_lines[i]; + int rec_to = rec->pos + rec->d.var[0].n - 1; // last position affected by the variant + if ( rec_to + args->snp_gap < last_from ) + j_flush++; + else if ( (var_type & VCF_INDEL) && (rec->d.var_type & VCF_SNP) && !(rec->d.var_type & SnpGap_set) ) + { + // this SNP has not been SnpGap-filtered yet + rec->d.var_type |= SnpGap_set; + bcf_add_filter(args->hdr, rec, args->SnpGap_id); + } + else if ( (var_type & VCF_SNP) && (rec->d.var_type & VCF_INDEL) ) + { + // the line which we are adding is a SNP and needs to be filtered + line->d.var_type |= SnpGap_set; + bcf_add_filter(args->hdr, line, args->SnpGap_id); + break; + } + } + } + flush_buffer(args, j_flush < k_flush ? j_flush : k_flush); +} + +static void set_genotypes(args_t *args, bcf1_t *line, int pass_site) +{ + int i,j; + if ( !bcf_hdr_nsamples(args->hdr) ) return; + if ( args->smpl_pass ) + { + int npass = 0; + for (i=0; ihdr); i++) npass += args->smpl_pass[i]; + + // return if all samples pass + if ( npass==bcf_hdr_nsamples(args->hdr) && (args->filter_logic & FLT_INCLUDE) ) return; + if ( npass==0 && (args->filter_logic & FLT_EXCLUDE) ) return; + } + else if ( pass_site ) return; + + int an = 0, has_an = bcf_get_info_int32(args->hdr, line, "AN", &args->tmp_ac, &args->ntmp_ac); + if ( has_an==1 ) an = args->tmp_ac[0]; + else has_an = 0; + + int has_ac = bcf_get_info_int32(args->hdr, line, "AC", &args->tmp_ac, &args->ntmp_ac); + has_ac = has_ac==line->n_allele-1 ? 1 : 0; + + int new_gt = 0, ngts = bcf_get_format_int32(args->hdr, line, "GT", &args->tmpi, &args->ntmpi); + ngts /= bcf_hdr_nsamples(args->hdr); + if ( args->set_gts==SET_GTS_MISSING ) new_gt = bcf_gt_missing; + else if ( args->set_gts==SET_GTS_REF ) new_gt = bcf_gt_unphased(0); + else error("todo: set_gts=%d\n", args->set_gts); + for (i=0; ihdr); i++) + { + if ( args->smpl_pass ) + { + int pass = args->smpl_pass[i]; + if ( args->filter_logic & FLT_EXCLUDE ) pass = pass ? 0 : 1; + if ( pass ) continue; + } + int32_t *gts = args->tmpi + ngts*i; + for (j=0; jset_gts==SET_GTS_MISSING && !bcf_gt_is_missing(gts[j]) ) + { + int ial = bcf_gt_allele(gts[j]); + if ( has_ac && ial>0 && ial<=line->n_allele ) args->tmp_ac[ ial-1 ]--; + an--; + } + else if ( args->set_gts==SET_GTS_REF ) + { + int ial = bcf_gt_allele(gts[j]); + if ( bcf_gt_is_missing(gts[j]) ) an++; + else if ( has_ac && ial>0 && ial<=line->n_allele ) args->tmp_ac[ ial-1 ]--; + } + gts[j] = new_gt; + } + } + bcf_update_genotypes(args->hdr,line,args->tmpi,ngts*bcf_hdr_nsamples(args->hdr)); + if ( has_an ) bcf_update_info_int32(args->hdr,line,"AN",&an,1); + if ( has_ac ) bcf_update_info_int32(args->hdr,line,"AC",args->tmp_ac,line->n_allele-1); +} + +static void usage(args_t *args) +{ + fprintf(stderr, "\n"); + fprintf(stderr, "About: Apply fixed-threshold filters.\n"); + fprintf(stderr, "Usage: bcftools filter [options] \n"); + fprintf(stderr, "\n"); + fprintf(stderr, "Options:\n"); + fprintf(stderr, " -e, --exclude exclude sites for which the expression is true (see man page for details)\n"); + fprintf(stderr, " -g, --SnpGap filter SNPs within base pairs of an indel\n"); + fprintf(stderr, " -G, --IndelGap filter clusters of indels separated by or fewer base pairs allowing only one to pass\n"); + fprintf(stderr, " -i, --include include only sites for which the expression is true (see man page for details\n"); + fprintf(stderr, " -m, --mode [+x] \"+\": do not replace but add to existing FILTER; \"x\": reset filters at sites which pass\n"); + fprintf(stderr, " --no-version do not append version and command line to the header\n"); + fprintf(stderr, " -o, --output write output to a file [standard output]\n"); + fprintf(stderr, " -O, --output-type b: compressed BCF, u: uncompressed BCF, z: compressed VCF, v: uncompressed VCF [v]\n"); + fprintf(stderr, " -r, --regions restrict to comma-separated list of regions\n"); + fprintf(stderr, " -R, --regions-file restrict to regions listed in a file\n"); + fprintf(stderr, " -s, --soft-filter annotate FILTER column with or unique filter name (\"Filter%%d\") made up by the program (\"+\")\n"); + fprintf(stderr, " -S, --set-GTs <.|0> set genotypes of failed samples to missing (.) or ref (0)\n"); + fprintf(stderr, " -t, --targets similar to -r but streams rather than index-jumps\n"); + fprintf(stderr, " -T, --targets-file similar to -R but streams rather than index-jumps\n"); + fprintf(stderr, " --threads number of extra output compression threads [0]\n"); + fprintf(stderr, "\n"); + exit(1); +} + +int main_vcffilter(int argc, char *argv[]) +{ + int c; + args_t *args = (args_t*) calloc(1,sizeof(args_t)); + args->argc = argc; args->argv = argv; + args->files = bcf_sr_init(); + args->output_fname = "-"; + args->output_type = FT_VCF; + args->n_threads = 0; + args->record_cmd_line = 1; + int regions_is_file = 0, targets_is_file = 0; + + static struct option loptions[] = + { + {"set-GTs",required_argument,NULL,'S'}, + {"mode",required_argument,NULL,'m'}, + {"soft-filter",required_argument,NULL,'s'}, + {"exclude",required_argument,NULL,'e'}, + {"include",required_argument,NULL,'i'}, + {"targets",required_argument,NULL,'t'}, + {"targets-file",required_argument,NULL,'T'}, + {"regions",required_argument,NULL,'r'}, + {"regions-file",required_argument,NULL,'R'}, + {"output",required_argument,NULL,'o'}, + {"output-type",required_argument,NULL,'O'}, + {"threads",required_argument,NULL,9}, + {"SnpGap",required_argument,NULL,'g'}, + {"IndelGap",required_argument,NULL,'G'}, + {"no-version",no_argument,NULL,8}, + {NULL,0,NULL,0} + }; + char *tmp; + while ((c = getopt_long(argc, argv, "e:i:t:T:r:R:h?s:m:o:O:g:G:S:",loptions,NULL)) >= 0) { + switch (c) { + case 'g': + args->snp_gap = strtol(optarg,&tmp,10); + if ( *tmp ) error("Could not parse argument: --SnpGap %s\n", optarg); + break; + case 'G': + args->indel_gap = strtol(optarg,&tmp,10); + if ( *tmp ) error("Could not parse argument: --IndelGap %s\n", optarg); + break; + case 'o': args->output_fname = optarg; break; + case 'O': + switch (optarg[0]) { + case 'b': args->output_type = FT_BCF_GZ; break; + case 'u': args->output_type = FT_BCF; break; + case 'z': args->output_type = FT_VCF_GZ; break; + case 'v': args->output_type = FT_VCF; break; + default: error("The output type \"%s\" not recognised\n", optarg); + } + break; + case 's': args->soft_filter = optarg; break; + case 'm': + if ( strchr(optarg,'x') ) args->annot_mode |= ANNOT_RESET; + if ( strchr(optarg,'+') ) args->annot_mode |= ANNOT_ADD; + break; + case 't': args->targets_list = optarg; break; + case 'T': args->targets_list = optarg; targets_is_file = 1; break; + case 'r': args->regions_list = optarg; break; + case 'R': args->regions_list = optarg; regions_is_file = 1; break; + case 'e': args->filter_str = optarg; args->filter_logic |= FLT_EXCLUDE; break; + case 'i': args->filter_str = optarg; args->filter_logic |= FLT_INCLUDE; break; + case 'S': + if ( !strcmp(".",optarg) ) args->set_gts = SET_GTS_MISSING; + else if ( !strcmp("0",optarg) ) args->set_gts = SET_GTS_REF; + else error("The argument to -S not recognised: %s\n", optarg); + break; + case 9 : args->n_threads = strtol(optarg, 0, 0); break; + case 8 : args->record_cmd_line = 0; break; + case 'h': + case '?': usage(args); + default: error("Unknown argument: %s\n", optarg); + } + } + + if ( args->filter_logic == (FLT_EXCLUDE|FLT_INCLUDE) ) error("Only one of -i or -e can be given.\n"); + char *fname = NULL; + if ( optind>=argc ) + { + if ( !isatty(fileno((FILE *)stdin)) ) fname = "-"; // reading from stdin + else usage(args); + } + else fname = argv[optind]; + + // read in the regions from the command line + if ( args->regions_list ) + { + args->files->require_index = 1; + if ( bcf_sr_set_regions(args->files, args->regions_list, regions_is_file)<0 ) + error("Failed to read the regions: %s\n", args->regions_list); + } + else if ( optind+1 < argc ) + { + int i; + kstring_t tmp = {0,0,0}; + kputs(argv[optind+1],&tmp); + for (i=optind+2; ifiles->require_index = 1; + if ( bcf_sr_set_regions(args->files, tmp.s, regions_is_file)<0 ) + error("Failed to read the regions: %s\n", args->regions_list); + free(tmp.s); + } + if ( args->targets_list ) + { + if ( bcf_sr_set_targets(args->files, args->targets_list,targets_is_file, 0)<0 ) + error("Failed to read the targets: %s\n", args->targets_list); + } + if ( !bcf_sr_add_reader(args->files, fname) ) error("Failed to open %s: %s\n", fname,bcf_sr_strerror(args->files->errnum)); + + init_data(args); + bcf_hdr_write(args->out_fh, args->hdr); + while ( bcf_sr_next_line(args->files) ) + { + bcf1_t *line = bcf_sr_get_line(args->files, 0); + int pass = 1; + if ( args->filter ) + { + pass = filter_test(args->filter, line, &args->smpl_pass); + if ( args->filter_logic & FLT_EXCLUDE ) pass = pass ? 0 : 1; + } + if ( args->soft_filter || args->set_gts || pass ) + { + if ( pass ) + { + bcf_unpack(line,BCF_UN_FLT); + if ( args->annot_mode & ANNOT_RESET || !line->d.n_flt ) bcf_add_filter(args->hdr, line, args->flt_pass); + } + else if ( args->soft_filter ) + { + if ( (args->annot_mode & ANNOT_ADD) ) bcf_add_filter(args->hdr, line, args->flt_fail); + else bcf_update_filter(args->hdr, line, &args->flt_fail, 1); + } + if ( args->set_gts ) set_genotypes(args, line, pass); + if ( !args->rbuf_lines ) + bcf_write1(args->out_fh, args->hdr, line); + else + buffered_filters(args, line); + } + } + buffered_filters(args, NULL); + + hts_close(args->out_fh); + destroy_data(args); + bcf_sr_destroy(args->files); + free(args); + return 0; +} diff --git a/vcfgtcheck.c b/vcfgtcheck.c new file mode 100644 index 0000000..8835db3 --- /dev/null +++ b/vcfgtcheck.c @@ -0,0 +1,822 @@ +/* vcfgtcheck.c -- Check sample identity. + + Copyright (C) 2013-2014 Genome Research Ltd. + + Author: Petr Danecek + +Permission is hereby granted, free of charge, to any person obtaining a copy +of this software and associated documentation files (the "Software"), to deal +in the Software without restriction, including without limitation the rights +to use, copy, modify, merge, publish, distribute, sublicense, and/or sell +copies of the Software, and to permit persons to whom the Software is +furnished to do so, subject to the following conditions: + +The above copyright notice and this permission notice shall be included in +all copies or substantial portions of the Software. + +THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE +AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER +LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, +OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN +THE SOFTWARE. */ + +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include "bcftools.h" +#include "hclust.h" + +typedef struct +{ + bcf_srs_t *files; // first reader is the query VCF - single sample normally or multi-sample for cross-check + bcf_hdr_t *gt_hdr, *sm_hdr; // VCF with genotypes to compare against and the query VCF + int ntmp_arr, npl_arr; + int32_t *tmp_arr, *pl_arr; + double *lks, *sites, min_inter_err, max_intra_err; + int *cnts, *dps, hom_only, cross_check, all_sites; + char *cwd, **argv, *gt_fname, *plot, *query_sample, *target_sample; + int argc, no_PLs, narr, nsmpl; +} +args_t; + +FILE *open_file(char **fname, const char *mode, const char *fmt, ...); +char *msprintf(const char *fmt, ...); +void mkdir_p(const char *fmt, ...); + +void py_plot(char *script) +{ + mkdir_p(script); + int len = strlen(script); + char *cmd = !strcmp(".py",script+len-3) ? msprintf("python %s", script) : msprintf("python %s.py", script); + int ret = system(cmd); + if ( ret ) fprintf(stderr, "The command returned non-zero status %d: %s\n", ret, cmd); + free(cmd); +} + +static void plot_check(args_t *args, char *target_sample, char *query_sample) +{ + char *fname; + FILE *fp = open_file(&fname, "w", "%s.py", args->plot); + fprintf(fp, + "import matplotlib as mpl\n" + "mpl.use('Agg')\n" + "import matplotlib.pyplot as plt\n" + "import matplotlib.gridspec as gridspec\n" + "import csv\n" + "csv.register_dialect('tab', delimiter='\\t', quoting=csv.QUOTE_NONE)\n" + "\n" + "sample_ids = False\n" + "\n" + "dat = []\n" + "with open('%s.tab', 'rb') as f:\n" + " reader = csv.reader(f, 'tab')\n" + " for row in reader:\n" + " if row[0][0]=='#': continue\n" + " if row[0]!='CN': continue\n" + " tgt = 0\n" + " if row[4]=='%s': tgt = 1\n" + " dat.append([float(row[1]), float(row[2]), float(row[3]), tgt, row[4]])\n" + "\n" + "dat = sorted(dat)\n" + "\n" + "iq = -1; dp = 0\n" + "for i in range(len(dat)):\n" + " if iq==-1 and dat[i][3]==1: iq = i\n" + " dp += dat[i][2]\n" + "dp /= len(dat)\n" + "\n" + "fig,ax1 = plt.subplots(figsize=(8,5))\n" + "ax2 = ax1.twinx()\n" + "plots = ax1.plot([x[0] for x in dat],'o-', ms=3, color='g', mec='g', label='Discordance (total)')\n" + "plots += ax1.plot([x[1] for x in dat], '^', ms=3, color='r', mec='r', label='Discordance (avg per site)')\n" + "plots += ax2.plot([x[2] for x in dat],'v', ms=3, color='k', label='Number of sites')\n" + "if iq!=-1:\n" + " ax1.plot([iq],[dat[iq][0]],'o',color='orange', ms=9)\n" + " ax1.annotate('%s',xy=(iq,dat[iq][0]), xytext=(5,5), textcoords='offset points',fontsize='xx-small',rotation=45,va='bottom',ha='left')\n" + " ax1.plot([iq],[dat[iq][1]],'^',color='red', ms=5)\n" + "for tl in ax1.get_yticklabels(): tl.set_color('g')\n" + "for tl in ax2.get_yticklabels(): tl.set_color('k'); tl.set_fontsize(9)\n" + "min_dp = min([x[2] for x in dat])\n" + "max_dp = max([x[2] for x in dat])\n" + "ax2.set_ylim(min_dp-1,max_dp+1)\n" + "ax1.set_title('Discordance with %s')\n" + "ax1.set_xlim(-0.05*len(dat),1.05*(len(dat)-1))\n" + "ax1.set_xlabel('Sample ID')\n" + "plt.subplots_adjust(left=0.1,right=0.9,bottom=0.1,top=0.9)\n" + "if sample_ids:\n" + " ax1.set_xticks(range(len(dat)))\n" + " ax1.set_xticklabels([x[4] for x in dat],**{'rotation':45, 'ha':'right', 'fontsize':8})\n" + " plt.subplots_adjust(bottom=0.2)\n" + "ax1.set_ylabel('Discordance',color='g')\n" + "ax2.set_ylabel('Number of sites',color='k')\n" + "ax2.ticklabel_format(style='sci', scilimits=(-3,2), axis='y')\n" + "ax1.ticklabel_format(style='sci', scilimits=(-3,2), axis='y')\n" + "labels = [l.get_label() for l in plots]\n" + "plt.legend(plots,labels,numpoints=1,markerscale=1,loc='best',prop={'size':10},frameon=False)\n" + "plt.savefig('%s.png')\n" + "plt.close()\n" + "\n", args->plot, target_sample, target_sample, query_sample, args->plot + ); + fclose(fp); + py_plot(fname); + free(fname); +} + +#if 0 +static void plot_cross_check(args_t *args) +{ + char *fname; + FILE *fp = open_file(&fname, "w", "%s.py", args->plot); + fprintf(fp, + "import matplotlib as mpl\n" + "mpl.use('Agg')\n" + "import matplotlib.pyplot as plt\n" + "import matplotlib.gridspec as gridspec\n" + "import csv\n" + "csv.register_dialect('tab', delimiter='\\t', quoting=csv.QUOTE_NONE)\n" + "avg = []\n" + "dp = []\n" + "sm2id = {}\n" + "dat = None\n" + "min = None\n" + "max = None\n" + "with open('%s.tab', 'rb') as f:\n" + " reader = csv.reader(f, 'tab')\n" + " i = 0\n" + " for row in reader:\n" + " if row[0]=='SM':\n" + " sm2id[row[4]] = i\n" + " avg.append([i,float(row[1])])\n" + " dp.append([i,float(row[2])])\n" + " i += 1\n" + " elif row[0]=='CN':\n" + " val = 0\n" + " if int(row[2])!=0: val = float(row[1])/int(row[2])\n" + " if not dat:\n" + " dat = [[0]*len(sm2id) for x in xrange(len(sm2id))]\n" + " min = val\n" + " max = val\n" + " id_i = sm2id[row[4]]\n" + " id_j = sm2id[row[5]]\n" + " dat[id_i][id_j] = val\n" + " dat[id_j][id_i] = val\n" + " if min > val: min = val\n" + " if max < val: max = val\n" + "\n" + "if len(sm2id)<=1: exit(1)\n" + "if min==max: exit(1)\n" + "\n" + "fig = plt.figure(figsize=(6,7))\n" + "gs = gridspec.GridSpec(2, 1, height_ratios=[1, 1.5])\n" + "ax1 = plt.subplot(gs[0])\n" + "ax2 = plt.subplot(gs[1])\n" + "\n" + "ax1.plot([x[0] for x in avg],[x[1] for x in avg],'^-', ms=3, color='k')\n" + "ax3 = ax1.twinx()\n" + "ax3.plot([x[0] for x in dp],[x[1] for x in dp],'^-', ms=3, color='r',mec='r')\n" + "for tl in ax3.get_yticklabels():\n" + " tl.set_color('r')\n" + " tl.set_fontsize(9)\n" + "\n" + "im = ax2.imshow(dat,clim=(min),interpolation='nearest',origin='lower')\n" + "cb1 = plt.colorbar(im,ax=ax2)\n" + "cb1.set_label('Pairwise discordance')\n" + "for t in cb1.ax.get_yticklabels(): t.set_fontsize(9)\n" + "\n" + "ax1.tick_params(axis='both', which='major', labelsize=9)\n" + "ax1.tick_params(axis='both', which='minor', labelsize=9)\n" + "ax2.tick_params(axis='both', which='major', labelsize=9)\n" + "ax2.tick_params(axis='both', which='minor', labelsize=9)\n" + "\n" + "ax1.set_title('Sample Discordance Score')\n" + "ax2.set_ylabel('Sample ID')\n" + "ax2.set_xlabel('Sample ID')\n" + "ax3.set_ylabel('Average Depth',color='r')\n" + "ax1.set_xlabel('Sample ID')\n" + "ax1.set_ylabel('Average discordance')\n" + "\n" + "plt.subplots_adjust(left=0.15,right=0.87,bottom=0.08,top=0.93,hspace=0.25)\n" + "plt.savefig('%s.png')\n" + "plt.close()\n" + "\n", args->plot,args->plot + ); + fclose(fp); + py_plot(fname); + free(fname); +} +#endif + +static void init_data(args_t *args) +{ + args->sm_hdr = args->files->readers[0].header; + if ( !bcf_hdr_nsamples(args->sm_hdr) ) error("No samples in %s?\n", args->files->readers[0].fname); + + if ( !args->cross_check ) + { + args->gt_hdr = args->files->readers[1].header; + int nsamples = bcf_hdr_nsamples(args->gt_hdr); + if ( !nsamples ) error("No samples in %s?\n", args->files->readers[1].fname); + args->lks = (double*) calloc(nsamples,sizeof(double)); + args->cnts = (int*) calloc(nsamples,sizeof(int)); + args->sites = (double*) calloc(nsamples,sizeof(double)); + args->dps = (int*) calloc(nsamples,sizeof(int)); + } +} + +static void destroy_data(args_t *args) +{ + free(args->lks); free(args->cnts); free(args->dps); free(args->cwd); free(args->sites); +} + +static int allele_to_int(bcf1_t *line, char *allele) +{ + int i; + for (i=0; in_allele; i++) + if ( !strcmp(allele,line->d.allele[i]) ) return i; + if ( strcmp(line->d.allele[i-1],"X") ) return -1; + return i-1; +} + +static int init_gt2ipl(args_t *args, bcf1_t *gt_line, bcf1_t *sm_line, int *gt2ipl, int n_gt2ipl) +{ + int i, j; + for (i=0; in_allele; i++) + { + // find which of the sm_alleles (k) corresponds to the gt_allele (i) + int k = allele_to_int(sm_line, gt_line->d.allele[i]); + if ( k<0 ) return 0; + for (j=0; j<=i; j++) + { + int l = allele_to_int(sm_line, gt_line->d.allele[j]); + if ( l<0 ) return 0; + gt2ipl[ bcf_ij2G(j,i) ] = k<=l ? bcf_ij2G(k,l) : bcf_ij2G(l,k); + } + } + //for (i=0; icwd = (char*) malloc(sizeof(char)*nbuf); + for (i=0; i<5; i++) + { + if ( (buf = getcwd(args->cwd, nbuf)) ) break; + nbuf *= 2; + args->cwd = (char*) realloc(args->cwd, sizeof(char)*nbuf); + } + assert(buf); +} + +static void print_header(args_t *args, FILE *fp) +{ + fprintf(fp, "# This file was produced by bcftools (%s+htslib-%s), the command line was:\n", bcftools_version(), hts_version()); + fprintf(fp, "# \t bcftools %s ", args->argv[0]); + int i; + for (i=1; iargc; i++) + fprintf(fp, " %s",args->argv[i]); + fprintf(fp, "\n# and the working directory was:\n"); + fprintf(fp, "# \t %s\n#\n", args->cwd); +} + +static int fake_PLs(args_t *args, bcf_hdr_t *hdr, bcf1_t *line) +{ + // PLs not present, use GTs instead. + int fake_PL = args->no_PLs ? args->no_PLs : 99; // with 1, discordance is the number of non-matching GTs + int nsm_gt, i; + if ( (nsm_gt=bcf_get_genotypes(hdr, line, &args->tmp_arr, &args->ntmp_arr)) <= 0 ) + error("GT not present at %s:%d?\n", hdr->id[BCF_DT_CTG][line->rid].key, line->pos+1); + nsm_gt /= bcf_hdr_nsamples(hdr); + int npl = line->n_allele*(line->n_allele+1)/2; + hts_expand(int,npl*bcf_hdr_nsamples(hdr),args->npl_arr,args->pl_arr); + for (i=0; itmp_arr + i*nsm_gt; + int j, *pl_ptr = args->pl_arr + i*npl; + if ( bcf_gt_is_missing(gt_ptr[0]) || bcf_gt_is_missing(gt_ptr[1]) ) // missing genotype + { + for (j=0; jno_PLs; + + // Initialize things: check which tags are defined in the header, sample names etc. + if ( bcf_hdr_id2int(args->gt_hdr, BCF_DT_ID, "GT")<0 ) error("[E::%s] GT not present in the header of %s?\n", __func__, args->files->readers[1].fname); + if ( bcf_hdr_id2int(args->sm_hdr, BCF_DT_ID, "PL")<0 ) + { + if ( bcf_hdr_id2int(args->sm_hdr, BCF_DT_ID, "GT")<0 ) + error("[E::%s] Neither PL nor GT present in the header of %s\n", __func__, args->files->readers[0].fname); + if ( !args->no_PLs ) + fprintf(stderr,"Warning: PL not present in the header of %s, using GT instead\n", args->files->readers[0].fname); + fake_pls = 1; + } + + FILE *fp = args->plot ? open_file(NULL, "w", "%s.tab", args->plot) : stdout; + print_header(args, fp); + + int tgt_isample = -1, query_isample = 0; + if ( args->target_sample ) + { + tgt_isample = bcf_hdr_id2int(args->gt_hdr, BCF_DT_SAMPLE, args->target_sample); + if ( tgt_isample<0 ) error("No such sample in %s: [%s]\n", args->files->readers[1].fname, args->target_sample); + } + if ( args->all_sites ) + { + if ( tgt_isample==-1 ) + { + fprintf(stderr,"No target sample selected for comparison, using the first sample in %s: %s\n", args->gt_fname,args->gt_hdr->samples[0]); + tgt_isample = 0; + } + } + if ( args->query_sample ) + { + query_isample = bcf_hdr_id2int(args->sm_hdr, BCF_DT_SAMPLE, args->query_sample); + if ( query_isample<0 ) error("No such sample in %s: [%s]\n", args->files->readers[0].fname, args->query_sample); + } + if ( args->all_sites ) + fprintf(fp, "# [1]SC, Site by Site Comparison\t[2]Chromosome\t[3]Position\t[4]-g alleles\t[5]-g GT (%s)\t[6]match log LK\t[7]Query alleles\t[8-]Query PLs (%s)\n", + args->gt_hdr->samples[tgt_isample],args->sm_hdr->samples[query_isample]); + + // Main loop + float prev_lk = 0; + while ( (ret=bcf_sr_next_line(args->files)) ) + { + if ( ret!=2 ) continue; + bcf1_t *sm_line = args->files->readers[0].buffer[0]; // the query file + bcf1_t *gt_line = args->files->readers[1].buffer[0]; // the -g target file + bcf_unpack(sm_line, BCF_UN_FMT); + bcf_unpack(gt_line, BCF_UN_FMT); + + // Init mapping from target genotype index to the sample's PL fields + int n_gt2ipl = gt_line->n_allele*(gt_line->n_allele + 1)/2; + if ( n_gt2ipl > m_gt2ipl ) + { + m_gt2ipl = n_gt2ipl; + gt2ipl = (int*) realloc(gt2ipl, sizeof(int)*m_gt2ipl); + } + if ( !init_gt2ipl(args, gt_line, sm_line, gt2ipl, n_gt2ipl) ) continue; + + // Target genotypes + int ngt, npl; + if ( (ngt=bcf_get_genotypes(args->gt_hdr, gt_line, >_arr, &ngt_arr)) <= 0 ) + error("GT not present at %s:%d?", args->gt_hdr->id[BCF_DT_CTG][gt_line->rid].key, gt_line->pos+1); + ngt /= bcf_hdr_nsamples(args->gt_hdr); + if ( ngt!=2 ) continue; // checking only diploid genotypes + + // Sample PLs + if ( !fake_pls ) + { + if ( (npl=bcf_get_format_int32(args->sm_hdr, sm_line, "PL", &args->pl_arr, &args->npl_arr)) <= 0 ) + { + if ( sm_line->n_allele==1 ) + { + // PL values may not be present when ALT=. (mpileup/bcftools output), in that case + // switch automatically to GT at these sites + npl = fake_PLs(args, args->sm_hdr, sm_line); + } + else + error("PL not present at %s:%d?\n", args->sm_hdr->id[BCF_DT_CTG][sm_line->rid].key, sm_line->pos+1); + } + else + npl /= bcf_hdr_nsamples(args->sm_hdr); + } + else + npl = fake_PLs(args, args->sm_hdr, sm_line); + + // Calculate likelihoods for all samples, assuming diploid genotypes + + // For faster access to genotype likelihoods (PLs) of the query sample + int max_ipl, *pl_ptr = args->pl_arr + query_isample*npl; + double sum_pl = 0; // for converting PLs to probs + for (max_ipl=0; max_iplno_PLs==1 ) sum_pl = -1; + + // The main stats: concordance of the query sample with the target -g samples + for (i=0; igt_hdr); i++) + { + int *gt_ptr = gt_arr + i*ngt; + if ( gt_ptr[1]==bcf_int32_vector_end ) continue; // skip haploid genotypes + if ( bcf_gt_is_missing(gt_ptr[0]) || bcf_gt_is_missing(gt_ptr[1]) ) continue; + int a = bcf_gt_allele(gt_ptr[0]); + int b = bcf_gt_allele(gt_ptr[1]); + if ( args->hom_only && a!=b ) continue; // heterozygous genotype + int igt_tgt = igt_tgt = bcf_alleles2gt(a,b); // genotype index in the target file + int igt_qry = gt2ipl[igt_tgt]; // corresponding genotype in query file + if ( igt_qry>=max_ipl || pl_ptr[igt_qry]<0 ) continue; // genotype not present in query sample: haploid or missing + args->lks[i] += sum_pl<0 ? -pl_ptr[igt_qry] : log(pow(10, -0.1*pl_ptr[igt_qry])/sum_pl); + args->sites[i]++; + } + if ( args->all_sites ) + { + // Print LKs at all sites for debugging + int *gt_ptr = gt_arr + tgt_isample*ngt; + if ( gt_ptr[1]==bcf_int32_vector_end ) continue; // skip haploid genotypes + int a = bcf_gt_allele(gt_ptr[0]); + int b = bcf_gt_allele(gt_ptr[1]); + if ( args->hom_only && a!=b ) continue; // heterozygous genotype + fprintf(fp, "SC\t%s\t%d", args->gt_hdr->id[BCF_DT_CTG][gt_line->rid].key, gt_line->pos+1); + for (i=0; in_allele; i++) fprintf(fp, "%c%s", i==0?'\t':',', gt_line->d.allele[i]); + fprintf(fp, "\t%s/%s", a>=0 ? gt_line->d.allele[a] : ".", b>=0 ? gt_line->d.allele[b] : "."); + fprintf(fp, "\t%f", args->lks[query_isample]-prev_lk); + prev_lk = args->lks[query_isample]; + + int igt, *pl_ptr = args->pl_arr + query_isample*npl; // PLs of the query sample + for (i=0; in_allele; i++) fprintf(fp, "%c%s", i==0?'\t':',', sm_line->d.allele[i]); + for (igt=0; igtpl_arr); + free(args->tmp_arr); + + // To be able to plot total discordance (=number of mismatching GTs with -G1) in the same + // plot as discordance per site, the latter must be scaled to the same range + int nsamples = bcf_hdr_nsamples(args->gt_hdr); + double extreme_lk = 0, extreme_lk_per_site = 0; + for (i=0; ilks[i] < extreme_lk ) extreme_lk = args->lks[i]; + if ( args->sites[i] && args->lks[i]/args->sites[i] < extreme_lk_per_site ) extreme_lk_per_site = args->lks[i]/args->sites[i]; + } + + // Sorted output + double **p = (double**) malloc(sizeof(double*)*nsamples); + for (i=0; ilks[i]; + qsort(p, nsamples, sizeof(int*), cmp_doubleptr); + + fprintf(fp, "# [1]CN\t[2]Discordance with %s (total)\t[3]Discordance (avg score per site)\t[4]Number of sites compared\t[5]Sample\t[6]Sample ID\n", args->sm_hdr->samples[query_isample]); + for (i=0; ilks; + double per_site = 0; + if ( args->sites[idx] ) + { + if ( args->sites[idx] && extreme_lk_per_site ) + { + per_site = args->lks[idx]/args->sites[idx]; + per_site *= extreme_lk / extreme_lk_per_site; + } + else + per_site = 0; + } + fprintf(fp, "CN\t%e\t%e\t%.0f\t%s\t%d\n", fabs(args->lks[idx]), fabs(per_site), args->sites[idx], args->gt_hdr->samples[idx], i); + } + + if ( args->plot ) + { + fclose(fp); + plot_check(args, args->target_sample ? args->target_sample : "", args->sm_hdr->samples[query_isample]); + } +} + +// static inline int is_hom_most_likely(int nals, int *pls) +// { +// int ia, ib, idx = 1, min_is_hom = 1, min_pl = pls[0]; +// for (ia=1; iasm_hdr, line, &args->tmp_arr, &args->ntmp_arr); + + if ( ngt<=0 ) return 1; // GT not present + if ( ngt!=args->nsmpl*2 ) return 2; // not diploid + ngt /= args->nsmpl; + + int i,j, idx = 0; + for (i=1; insmpl; i++) + { + int32_t *a = args->tmp_arr + i*ngt; + if ( bcf_gt_is_missing(a[0]) || bcf_gt_is_missing(a[1]) || a[1]==bcf_int32_vector_end ) { idx+=i; continue; } + int agt = 1<tmp_arr + j*ngt; + if ( bcf_gt_is_missing(b[0]) || bcf_gt_is_missing(b[1]) || b[1]==bcf_int32_vector_end ) { idx++; continue; } + int bgt = 1<sm_hdr, line, "PL", &args->tmp_arr, &args->ntmp_arr); + + if ( npl<=0 ) return 1; // PL not present + npl /= args->nsmpl; + + int i,j,k, idx = 0; + for (i=1; insmpl; i++) + { + int32_t *a = args->tmp_arr + i*npl; + int imin = -1; + for (k=0; k a[k] ) imin = k; + } + if ( imin<0 ) { idx+=i; continue; } + + for (j=0; jtmp_arr + j*npl; + int jmin = -1; + for (k=0; k b[k] ) jmin = k; + } + if ( jmin<0 ) { idx++; continue; } + + ntot[idx]++; + if ( imin!=jmin ) ndif[idx]++; + idx++; + } + } + return 0; +} + +static void cross_check_gts(args_t *args) +{ + // Initialize things: check which tags are defined in the header, sample names etc. + if ( bcf_hdr_id2int(args->sm_hdr, BCF_DT_ID, "PL")<0 ) + { + if ( bcf_hdr_id2int(args->sm_hdr, BCF_DT_ID, "GT")<0 ) + error("[E::%s] Neither PL nor GT present in the header of %s\n", __func__, args->files->readers[0].fname); + if ( !args->no_PLs ) { + fprintf(stderr,"Warning: PL not present in the header of %s, using GT instead\n", args->files->readers[0].fname); + args->no_PLs = 99; + } + } + + args->nsmpl = bcf_hdr_nsamples(args->sm_hdr); + args->narr = (args->nsmpl-1)*args->nsmpl/2; + + uint32_t *ndif = (uint32_t*) calloc(args->narr,4); + uint32_t *ntot = (uint32_t*) calloc(args->narr,4); + + while ( bcf_sr_next_line(args->files) ) + { + bcf1_t *line = bcf_sr_get_line(args->files,0); + + // use PLs unless no_PLs is set and GT exists + if ( args->no_PLs ) + { + if ( process_GT(args,line,ntot,ndif)==0 ) continue; + } + process_PL(args,line,ntot,ndif); + } + + FILE *fp = stdout; + print_header(args, fp); + + float *tmp = (float*)malloc(sizeof(float)*args->nsmpl*(args->nsmpl-1)/2); + + // Output pairwise distances + fprintf(fp, "# ERR, error rate\t[2]Pairwise error rate\t[3]Number of sites compared\t[4]Sample i\t[5]Sample j\n"); + int i,j, idx = 0; + for (i=0; insmpl; i++) + { + for (j=0; jsm_hdr->samples[i],args->sm_hdr->samples[j]); + PDIST(tmp,i,j) = err; + idx++; + } + } + + // Cluster samples + int nlist; + float clust_max_err = args->max_intra_err; + hclust_t *clust = hclust_init(args->nsmpl,tmp); + cluster_t *list = hclust_create_list(clust,args->min_inter_err,&clust_max_err,&nlist); + fprintf(fp, "# CLUSTER\t[2]Maximum inter-cluster ERR\t[3-]List of samples\n"); + for (i=0; ism_hdr->samples[list[i].memb[j]]); + fprintf(fp,"\n"); + } + hclust_destroy_list(list,nlist); + // Debugging output: the cluster graph and data used for deciding + char **dbg = hclust_explain(clust,&nlist); + for (i=0; ism_hdr->samples,clust_max_err)); + hclust_destroy(clust); + free(tmp); + + + // Deprecated output for temporary backward compatibility + fprintf(fp, "# Warning: The CN block is deprecated and will be removed in future releases. Use ERR instead.\n"); + fprintf(fp, "# [1]CN\t[2]Discordance\t[3]Number of sites\t[4]Average minimum depth\t[5]Sample i\t[6]Sample j\n"); + idx = 0; + for (i=0; insmpl; i++) + { + for (j=0; jsm_hdr->samples[i],args->sm_hdr->samples[j]); + idx++; + } + } + + free(ndif); + free(ntot); + free(args->tmp_arr); +} + +static char *init_prefix(char *prefix) +{ + int len = strlen(prefix); + if ( prefix[len-1] == '/' || prefix[len-1] == '\\' ) + return msprintf("%sgtcheck", prefix); + return strdup(prefix); +} + +static void usage(void) +{ + fprintf(stderr, "\n"); + fprintf(stderr, "About: Check sample identity. With no -g BCF given, multi-sample cross-check is performed.\n"); + fprintf(stderr, "Usage: bcftools gtcheck [options] [-g ] \n"); + fprintf(stderr, "\n"); + fprintf(stderr, "Options:\n"); + fprintf(stderr, " -a, --all-sites output comparison for all sites\n"); + fprintf(stderr, " -c, --cluster min inter- and max intra-sample error [0.23,-0.3]\n"); + fprintf(stderr, " -g, --genotypes genotypes to compare against\n"); + fprintf(stderr, " -G, --GTs-only use GTs, ignore PLs, using for unseen genotypes [99]\n"); + fprintf(stderr, " -H, --homs-only homozygous genotypes only (useful for low coverage data)\n"); + fprintf(stderr, " -p, --plot plot\n"); + fprintf(stderr, " -r, --regions restrict to comma-separated list of regions\n"); + fprintf(stderr, " -R, --regions-file restrict to regions listed in a file\n"); + fprintf(stderr, " -s, --query-sample query sample (by default the first sample is checked)\n"); + fprintf(stderr, " -S, --target-sample target sample in the -g file (used only for plotting)\n"); + fprintf(stderr, " -t, --targets similar to -r but streams rather than index-jumps\n"); + fprintf(stderr, " -T, --targets-file similar to -R but streams rather than index-jumps\n"); + fprintf(stderr, "\n"); + exit(1); +} + +int main_vcfgtcheck(int argc, char *argv[]) +{ + int c; + args_t *args = (args_t*) calloc(1,sizeof(args_t)); + args->files = bcf_sr_init(); + args->argc = argc; args->argv = argv; set_cwd(args); + char *regions = NULL, *targets = NULL; + int regions_is_file = 0, targets_is_file = 0; + + // In simulated sample swaps the minimum error was 0.3 and maximum intra-sample error was 0.23 + // - min_inter: pairs with smaller err value will be considered identical + // - max_intra: pairs with err value bigger than abs(max_intra_err) will be considered + // different. If negative, the cutoff may be heuristically lowered + args->min_inter_err = 0.23; + args->max_intra_err = -0.3; + + static struct option loptions[] = + { + {"cluster",1,0,'c'}, + {"GTs-only",1,0,'G'}, + {"all-sites",0,0,'a'}, + {"homs-only",0,0,'H'}, + {"help",0,0,'h'}, + {"genotypes",1,0,'g'}, + {"plot",1,0,'p'}, + {"target-sample",1,0,'S'}, + {"query-sample",1,0,'s'}, + {"regions",1,0,'r'}, + {"regions-file",1,0,'R'}, + {"targets",1,0,'t'}, + {"targets-file",1,0,'T'}, + {0,0,0,0} + }; + char *tmp; + while ((c = getopt_long(argc, argv, "hg:p:s:S:Hr:R:at:T:G:c:",loptions,NULL)) >= 0) { + switch (c) { + case 'c': + args->min_inter_err = strtod(optarg,&tmp); + if ( *tmp ) + { + if ( *tmp!=',') error("Could not parse: -c %s\n", optarg); + args->max_intra_err = strtod(tmp+1,&tmp); + if ( *tmp ) error("Could not parse: -c %s\n", optarg); + } + break; + case 'G': + args->no_PLs = strtol(optarg,&tmp,10); + if ( *tmp ) error("Could not parse argument: --GTs-only %s\n", optarg); + break; + case 'a': args->all_sites = 1; break; + case 'H': args->hom_only = 1; break; + case 'g': args->gt_fname = optarg; break; + case 'p': args->plot = optarg; break; + case 'S': args->target_sample = optarg; break; + case 's': args->query_sample = optarg; break; + case 'r': regions = optarg; break; + case 'R': regions = optarg; regions_is_file = 1; break; + case 't': targets = optarg; break; + case 'T': targets = optarg; targets_is_file = 1; break; + case 'h': + case '?': usage(); + default: error("Unknown argument: %s\n", optarg); + } + } + char *fname = NULL; + if ( optind==argc ) + { + if ( !isatty(fileno((FILE *)stdin)) ) fname = "-"; // reading from stdin + else usage(); // no files given + } + else fname = argv[optind]; + if ( argc>optind+1 ) usage(); // too many files given + if ( !args->gt_fname ) args->cross_check = 1; // no genotype file, run in cross-check mode + else args->files->require_index = 1; + if ( regions && bcf_sr_set_regions(args->files, regions, regions_is_file)<0 ) error("Failed to read the regions: %s\n", regions); + if ( targets && bcf_sr_set_targets(args->files, targets, targets_is_file, 0)<0 ) error("Failed to read the targets: %s\n", targets); + if ( !bcf_sr_add_reader(args->files, fname) ) error("Failed to open %s: %s\n", fname,bcf_sr_strerror(args->files->errnum)); + if ( args->gt_fname && !bcf_sr_add_reader(args->files, args->gt_fname) ) error("Failed to open %s: %s\n", args->gt_fname,bcf_sr_strerror(args->files->errnum)); + args->files->collapse = COLLAPSE_SNPS|COLLAPSE_INDELS; + if ( args->plot ) args->plot = init_prefix(args->plot); + init_data(args); + if ( args->cross_check ) + cross_check_gts(args); + else + check_gt(args); + destroy_data(args); + bcf_sr_destroy(args->files); + if (args->plot) free(args->plot); + free(args); + return 0; +} + diff --git a/vcfindex.c b/vcfindex.c new file mode 100644 index 0000000..aa60fb2 --- /dev/null +++ b/vcfindex.c @@ -0,0 +1,224 @@ +/* vcfindex.c -- Index bgzip compressed VCF/BCF files for random access. + + Copyright (C) 2014-2016 Genome Research Ltd. + + Author: Shane McCarthy + +Permission is hereby granted, free of charge, to any person obtaining a copy +of this software and associated documentation files (the "Software"), to deal +in the Software without restriction, including without limitation the rights +to use, copy, modify, merge, publish, distribute, sublicense, and/or sell +copies of the Software, and to permit persons to whom the Software is +furnished to do so, subject to the following conditions: + +The above copyright notice and this permission notice shall be included in +all copies or substantial portions of the Software. + +THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL +THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER +LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING +FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER +DEALINGS IN THE SOFTWARE. */ + +#include +#include +#include +#include +#include +#include +#include +#define __STDC_FORMAT_MACROS +#include +#include +#include "bcftools.h" + +#define BCF_LIDX_SHIFT 14 + +static void usage(void) +{ + fprintf(stderr, "\n"); + fprintf(stderr, "About: Index bgzip compressed VCF/BCF files for random access.\n"); + fprintf(stderr, "Usage: bcftools index [options] |\n"); + fprintf(stderr, "\n"); + fprintf(stderr, "Indexing options:\n"); + fprintf(stderr, " -c, --csi generate CSI-format index for VCF/BCF files [default]\n"); + fprintf(stderr, " -f, --force overwrite index if it already exists\n"); + fprintf(stderr, " -m, --min-shift INT set minimal interval size for CSI indices to 2^INT [14]\n"); + fprintf(stderr, " -o, --output-file FILE optional output index file name\n"); + fprintf(stderr, " -t, --tbi generate TBI-format index for VCF files\n"); + fprintf(stderr, " --threads sets the number of threads [0]\n"); + fprintf(stderr, "\n"); + fprintf(stderr, "Stats options:\n"); + fprintf(stderr, " -n, --nrecords print number of records based on existing index file\n"); + fprintf(stderr, " -s, --stats print per contig stats based on existing index file\n"); + fprintf(stderr, "\n"); + exit(1); +} + +int vcf_index_stats(char *fname, int stats) +{ + const char **seq; + int i, nseq; + tbx_t *tbx = NULL; + hts_idx_t *idx = NULL; + + htsFile *fp = hts_open(fname,"r"); + if ( !fp ) { fprintf(stderr,"Could not read %s\n", fname); return 1; } + bcf_hdr_t *hdr = bcf_hdr_read(fp); + if ( !hdr ) { fprintf(stderr,"Could not read the header: %s\n", fname); return 1; } + + if ( hts_get_format(fp)->format==vcf ) + { + tbx = tbx_index_load(fname); + if ( !tbx ) { fprintf(stderr,"Could not load index for VCF: %s\n", fname); return 1; } + } + else if ( hts_get_format(fp)->format==bcf ) + { + idx = bcf_index_load(fname); + if ( !idx ) { fprintf(stderr,"Could not load index for BCF file: %s\n", fname); return 1; } + } + else + { + fprintf(stderr,"Could not detect the file type as VCF or BCF: %s\n", fname); + return 1; + } + + seq = tbx ? tbx_seqnames(tbx, &nseq) : bcf_index_seqnames(idx, hdr, &nseq); + uint64_t sum = 0; + for (i=0; iidx : idx, i, &records, &v); + sum+=records; + if (stats&2 || !records) continue; + bcf_hrec_t *hrec = bcf_hdr_get_hrec(hdr, BCF_HL_CTG, "ID", seq[i], NULL); + int hkey = hrec ? bcf_hrec_find_key(hrec, "length") : -1; + printf("%s\t%s\t%" PRIu64 "\n", seq[i], hkey<0?".":hrec->vals[hkey], records); + } + if (!sum) + { + // No counts found. + // Is this because index version has no stored count data, or no records? + bcf1_t *rec = bcf_init1(); + if (bcf_read1(fp, hdr, rec) >= 0) + { + fprintf(stderr,"index of %s does not contain any count metadata. Please re-index with a newer version of bcftools or tabix.\n", fname); + return 1; + } + bcf_destroy1(rec); + } + if (stats&2) printf("%" PRIu64 "\n", sum); + free(seq); + hts_close(fp); + bcf_hdr_destroy(hdr); + if (tbx) + tbx_destroy(tbx); + if (idx) + hts_idx_destroy(idx); + return 0; +} + +int main_vcfindex(int argc, char *argv[]) +{ + int c, force = 0, tbi = 0, stats = 0, n_threads = 0; + int min_shift = BCF_LIDX_SHIFT; + char *outfn = NULL; + + static struct option loptions[] = + { + {"csi",no_argument,NULL,'c'}, + {"tbi",no_argument,NULL,'t'}, + {"force",no_argument,NULL,'f'}, + {"min-shift",required_argument,NULL,'m'}, + {"stats",no_argument,NULL,'s'}, + {"nrecords",no_argument,NULL,'n'}, + {"threads",required_argument,NULL,9}, + {"output-file",required_argument,NULL,'o'}, + {NULL, 0, NULL, 0} + }; + + char *tmp; + while ((c = getopt_long(argc, argv, "ctfm:sno:", loptions, NULL)) >= 0) + { + switch (c) + { + case 'c': tbi = 0; break; + case 't': tbi = 1; min_shift = 0; break; + case 'f': force = 1; break; + case 'm': + min_shift = strtol(optarg,&tmp,10); + if ( *tmp ) error("Could not parse argument: --min-shift %s\n", optarg); + break; + case 's': stats |= 1; break; + case 'n': stats |= 2; break; + case 9: + n_threads = strtol(optarg,&tmp,10); + if ( *tmp ) error("Could not parse argument: --threads %s\n", optarg); + break; + case 'o': outfn = optarg; break; + default: usage(); + } + } + if (stats>2) + { + fprintf(stderr, "[E::%s] expected only one of --stats or --nrecords options\n", __func__); + return 1; + } + if (tbi && min_shift>0) + { + fprintf(stderr, "[E::%s] min-shift option only expected for CSI indices \n", __func__); + return 1; + } + if (min_shift < 0 || min_shift > 30) + { + fprintf(stderr, "[E::%s] expected min_shift in range [0,30] (%d)\n", __func__, min_shift); + return 1; + } + + char *fname = NULL; + if ( optind>=argc ) + { + if ( !isatty(fileno((FILE *)stdin)) ) fname = "-"; // reading from stdin + else usage(); + } + else fname = argv[optind]; + if (stats) return vcf_index_stats(fname, stats); + + kstring_t idx_fname = {0,0,0}; + if (outfn) + kputs(outfn,&idx_fname); + else + { + if (!strcmp(fname, "-")) { fprintf(stderr, "[E::%s] must specify an output path for index file when reading VCF/BCF from stdin\n", __func__); return 1; } + ksprintf(&idx_fname, "%s.%s", fname, tbi ? "tbi" : "csi"); + } + if (!force) + { + // Before complaining about existing index, check if the VCF file isn't newer. + struct stat stat_tbi, stat_file; + if ( stat(idx_fname.s, &stat_tbi)==0 ) + { + stat(fname, &stat_file); + if ( stat_file.st_mtime <= stat_tbi.st_mtime ) + { + fprintf(stderr,"[E::%s] the index file exists. Please use '-f' to overwrite %s\n", __func__, idx_fname.s); + free(idx_fname.s); + return 1; + } + } + } + + int ret = bcf_index_build3(fname, idx_fname.s, min_shift, n_threads); + free(idx_fname.s); + if (ret != 0) { + if (ret == -2) + error("index: failed to open \"%s\"\n", fname); + else if (ret == -3) + error("index: \"%s\" is in a format that cannot be usefully indexed\n", fname); + else + error("index: failed to create index for \"%s\"\n", fname); + } + return 0; +} diff --git a/vcfisec.c b/vcfisec.c new file mode 100644 index 0000000..9eb3a7c --- /dev/null +++ b/vcfisec.c @@ -0,0 +1,600 @@ +/* vcfisec.c -- Create intersections, unions and complements of VCF files. + + Copyright (C) 2012-2014 Genome Research Ltd. + + Author: Petr Danecek + +Permission is hereby granted, free of charge, to any person obtaining a copy +of this software and associated documentation files (the "Software"), to deal +in the Software without restriction, including without limitation the rights +to use, copy, modify, merge, publish, distribute, sublicense, and/or sell +copies of the Software, and to permit persons to whom the Software is +furnished to do so, subject to the following conditions: + +The above copyright notice and this permission notice shall be included in +all copies or substantial portions of the Software. + +THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE +AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER +LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, +OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN +THE SOFTWARE. */ + +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include "bcftools.h" +#include "filter.h" + +#define OP_PLUS 1 +#define OP_MINUS 2 +#define OP_EQUAL 3 +#define OP_VENN 4 +#define OP_COMPLEMENT 5 +#define OP_EXACT 6 + +// Logic of the filters: include or exclude sites which match the filters? +#define FLT_INCLUDE 1 +#define FLT_EXCLUDE 2 + +typedef struct +{ + int isec_op, isec_n, *write, iwrite, nwrite, output_type, n_threads; + int nflt, *flt_logic; + filter_t **flt; + char **flt_expr; + bcf_srs_t *files; + FILE *fh_log, *fh_sites; + htsFile **fh_out; + char **argv, *prefix, *output_fname, **fnames, *write_files, *targets_list, *regions_list; + char *isec_exact; + int argc, record_cmd_line; +} +args_t; + +/** + * mkdir_p() - create new directory for a file $fname + * @fname: the file name to create the directory for, the part after last "/" is ignored + */ +void mkdir_p(const char *fmt, ...) +{ + va_list ap; + va_start(ap, fmt); + int n = vsnprintf(NULL, 0, fmt, ap) + 2; + va_end(ap); + + char *path = (char*)malloc(n); + va_start(ap, fmt); + vsnprintf(path, n, fmt, ap); + va_end(ap); + + char *tmp = strdup(path), *p = tmp+1; + while (*p) + { + while (*p && *p!='/') p++; + if ( *p ) + { + *p = 0; + mkdir(tmp,S_IRWXU | S_IRWXG | S_IROTH | S_IXOTH); + *p = '/'; + p++; + } + } + free(tmp); + free(path); +} + +/** + * open_file() - open new file creating the file name using vsnprintf + * @fname: if not NULL, on output will point to newly allocated fname string + * @mode: if NULL, only the file name string will be created + * @fmt: vsnprintf format and args + * + * Returns open file descriptor or NULL if mode is NULL. + */ +FILE *open_file(char **fname, const char *mode, const char *fmt, ...) +{ + va_list ap; + va_start(ap, fmt); + int n = vsnprintf(NULL, 0, fmt, ap) + 2; + va_end(ap); + + char *str = (char*)malloc(n); + va_start(ap, fmt); + vsnprintf(str, n, fmt, ap); + va_end(ap); + + mkdir_p(str); + if ( !mode ) + { + if ( !fname ) error("Uh: expected fname or mode\n"); + *fname = str; + return NULL; + } + + FILE *fp = fopen(str,mode); + if ( fname ) *fname = str; + else free(str); + return fp; +} + +void isec_vcf(args_t *args) +{ + bcf_srs_t *files = args->files; + kstring_t str = {0,0,0}; + htsFile *out_fh = NULL; + + // When only one VCF is output, print VCF to stdout or -o file + int out_std = 0; + if ( args->nwrite==1 && !args->prefix ) out_std = 1; + if ( args->targets_list && files->nreaders==1 ) out_std = 1; + if ( out_std ) + { + out_fh = hts_open(args->output_fname? args->output_fname : "-",hts_bcf_wmode(args->output_type)); + if ( out_fh == NULL ) error("Can't write to %s: %s\n", args->output_fname? args->output_fname : "standard output", strerror(errno)); + if ( args->n_threads ) hts_set_threads(out_fh, args->n_threads); + if (args->record_cmd_line) bcf_hdr_append_version(files->readers[args->iwrite].header,args->argc,args->argv,"bcftools_isec"); + bcf_hdr_write(out_fh, files->readers[args->iwrite].header); + } + if ( !args->nwrite && !out_std && !args->prefix ) + fprintf(stderr,"Note: -w option not given, printing list of sites...\n"); + + int n; + while ( (n=bcf_sr_next_line(files)) ) + { + bcf_sr_t *reader = NULL; + bcf1_t *line = NULL; + int i, ret = 0; + for (i=0; inreaders; i++) + { + if ( !bcf_sr_has_line(files,i) ) continue; + + if ( args->nflt && args->flt[i] ) + { + bcf1_t *rec = bcf_sr_get_line(files, i); + int pass = filter_test(args->flt[i], rec, NULL); + if ( args->flt_logic[i] & FLT_EXCLUDE ) pass = pass ? 0 : 1; + if ( !pass ) + { + files->has_line[i] = 0; + n--; + continue; + } + } + + if ( !line ) + { + line = files->readers[i].buffer[0]; + reader = &files->readers[i]; + } + ret |= 1<isec_op) + { + case OP_COMPLEMENT: if ( n!=1 || !bcf_sr_has_line(files,0) ) continue; break; + case OP_EQUAL: if ( n != args->isec_n ) continue; break; + case OP_PLUS: if ( n < args->isec_n ) continue; break; + case OP_MINUS: if ( n > args->isec_n ) continue; break; + case OP_EXACT: + for (i=0; inreaders; i++) + if ( files->has_line[i] != args->isec_exact[i] ) break; + if ( inreaders ) continue; + break; + } + + if ( out_std ) + { + if ( bcf_sr_has_line(files,args->iwrite) ) + bcf_write1(out_fh, files->readers[args->iwrite].header, files->readers[args->iwrite].buffer[0]); + continue; + } + else if ( args->fh_sites ) + { + str.l = 0; + kputs(reader->header->id[BCF_DT_CTG][line->rid].key, &str); kputc('\t', &str); + kputw(line->pos+1, &str); kputc('\t', &str); + if (line->n_allele > 0) kputs(line->d.allele[0], &str); + else kputc('.', &str); + kputc('\t', &str); + if (line->n_allele > 1) kputs(line->d.allele[1], &str); + else kputc('.', &str); + for (i=2; in_allele; i++) + { + kputc(',', &str); + kputs(line->d.allele[i], &str); + } + kputc('\t', &str); + for (i=0; inreaders; i++) + kputc(bcf_sr_has_line(files,i)?'1':'0', &str); + kputc('\n', &str); + fwrite(str.s,sizeof(char),str.l,args->fh_sites); + } + + if ( args->prefix ) + { + if ( args->isec_op==OP_VENN && ret==3 ) + { + if ( !args->nwrite || args->write[0] ) + bcf_write1(args->fh_out[2], bcf_sr_get_header(files,0), bcf_sr_get_line(files,0)); + if ( !args->nwrite || args->write[1] ) + bcf_write1(args->fh_out[3], bcf_sr_get_header(files,1), bcf_sr_get_line(files,1)); + } + else + { + for (i=0; inreaders; i++) + { + if ( !bcf_sr_has_line(files,i) ) continue; + if ( args->write && !args->write[i] ) continue; + bcf_write1(args->fh_out[i], files->readers[i].header, files->readers[i].buffer[0]); + } + } + } + } + if ( str.s ) free(str.s); + if ( out_fh ) hts_close(out_fh); +} + +static void add_filter(args_t *args, char *expr, int logic) +{ + args->nflt++; + args->flt_expr = (char**) realloc(args->flt_expr,sizeof(char*)*args->nflt); + args->flt_logic = (int*) realloc(args->flt_logic,sizeof(int)*args->nflt); + args->flt = (filter_t**) realloc(args->flt,sizeof(filter_t*)*args->nflt); + if ( expr[0]=='-' && expr[1]==0 ) + { + args->flt_expr[args->nflt-1] = NULL; + args->flt[args->nflt-1] = NULL; + } + else + args->flt_expr[args->nflt-1] = expr; + args->flt_logic[args->nflt-1] = logic; +} + +static void destroy_data(args_t *args); +static void init_data(args_t *args) +{ + int i; + if ( args->nflt ) + { + if ( args->nflt > 1 && args->nflt!=args->files->nreaders ) + error("Error: expected either one -i/-e option or as many as there are input files\n"); + if ( args->nflt < args->files->nreaders ) + { + if ( !args->flt_expr[0] ) error("Error: useless use of -i/-e\n"); + args->nflt = args->files->nreaders; + args->flt_expr = (char**) realloc(args->flt_expr,sizeof(char*)*args->nflt); + args->flt_logic = (int*) realloc(args->flt_logic,sizeof(int)*args->nflt); + args->flt = (filter_t**) realloc(args->flt,sizeof(filter_t*)*args->nflt); + for (i=1; inflt; i++) + { + args->flt_expr[i] = args->flt_expr[0]; + args->flt_logic[i] = args->flt_logic[0]; + args->flt[i] = filter_init(args->files->readers[i].header,args->flt_expr[i]); + } + args->flt[0] = filter_init(args->files->readers[0].header,args->flt_expr[0]); + } + else + { + for (i=0; ifiles->nreaders; i++) + { + if ( !args->flt_expr[i] ) continue; + args->flt[i] = filter_init(args->files->readers[i].header,args->flt_expr[i]); + } + } + } + + if ( args->isec_op==OP_EXACT ) + { + if ( strlen(args->isec_exact)!=args->files->nreaders ) + error("The number of files does not match the bitmask: %d vs %s\n", args->files->nreaders,args->isec_exact); + for (i=0; ifiles->nreaders; i++) + if ( args->isec_exact[i]!='0' && args->isec_exact[i]!='1' ) error("Unexpected bitmask: %s\n",args->isec_exact); + for (i=0; ifiles->nreaders; i++) + args->isec_exact[i] -= '0'; + } + + // Which files to write: parse the string passed with -w + char *p = args->write_files; + while (p && *p) + { + if ( !args->write ) args->write = (int*) calloc(args->files->nreaders,sizeof(int)); + if ( sscanf(p,"%d",&i)!=1 ) error("Could not parse --write %s\n", args->write_files); + if ( i<0 || i>args->files->nreaders ) error("The index is out of range: %d (%s)\n", i, args->write_files); + args->write[i-1] = 1; + args->iwrite = i-1; + args->nwrite++; + while (*p && *p!=',') p++; + if ( *p==',' ) p++; + } + if ( args->nwrite>1 && !args->prefix ) error("Expected -p when multiple output files given: --write %s\n", args->write_files); + if ( args->isec_op==OP_COMPLEMENT && args->nwrite ) + { + if ( args->nwrite>1 ) error("Multiple files to -w make no sense with -C\n"); + if ( !args->write[0] ) error("Only -w1 makes sense with -C\n"); + } + + if ( args->prefix ) + { + // Init output directory and create the readme file + args->fh_log = open_file(NULL,"w","%s/README.txt", args->prefix); + if ( !args->fh_log ) error("%s/README.txt: %s\n", args->prefix, strerror(errno)); + + fprintf(args->fh_log,"This file was produced by vcfisec.\n"); + fprintf(args->fh_log,"The command line was:\tbcftools %s ", args->argv[0]); + int i; + for (i=1; iargc; i++) fprintf(args->fh_log," %s",args->argv[i]); + fprintf(args->fh_log,"\n\nUsing the following file names:\n"); + + const char *suffix = "vcf"; + if ( args->output_type & FT_BCF ) suffix = "bcf"; + else if ( args->output_type & FT_GZ ) suffix = "vcf.gz"; + + // Open output files and write the legend + if ( args->isec_op==OP_VENN ) + { + args->fh_out = (htsFile**) malloc(sizeof(htsFile*)*4); + args->fnames = (char**) calloc(4,sizeof(char*)); + + #define OPEN_FILE(i,j) { \ + open_file(&args->fnames[i], NULL, "%s/%04d.%s", args->prefix, i, suffix); \ + args->fh_out[i] = hts_open(args->fnames[i], hts_bcf_wmode(args->output_type)); \ + if ( !args->fh_out[i] ) error("Could not open %s\n", args->fnames[i]); \ + if ( args->n_threads ) hts_set_threads(args->fh_out[i], args->n_threads); \ + if (args->record_cmd_line) bcf_hdr_append_version(args->files->readers[j].header,args->argc,args->argv,"bcftools_isec"); \ + bcf_hdr_write(args->fh_out[i], args->files->readers[j].header); \ + } + if ( !args->nwrite || args->write[0] ) + { + OPEN_FILE(0,0); + fprintf(args->fh_log,"%s\tfor records private to\t%s\n", args->fnames[0], args->files->readers[0].fname); + } + if ( !args->nwrite || args->write[1] ) + { + OPEN_FILE(1,1); + fprintf(args->fh_log,"%s\tfor records private to\t%s\n", args->fnames[1], args->files->readers[1].fname); + } + if ( !args->nwrite || args->write[0] ) + { + OPEN_FILE(2,0); + fprintf(args->fh_log,"%s\tfor records from %s shared by both\t%s %s\n", args->fnames[2], args->files->readers[0].fname, args->files->readers[0].fname, args->files->readers[1].fname); + } + if ( !args->nwrite || args->write[1] ) + { + OPEN_FILE(3,1); + fprintf(args->fh_log,"%s\tfor records from %s shared by both\t%s %s\n", args->fnames[3], args->files->readers[1].fname, args->files->readers[0].fname, args->files->readers[1].fname); + } + } + else + { + // Init one output file for each reader + args->fh_out = (htsFile**) calloc(args->files->nreaders, sizeof(htsFile*)); + args->fnames = (char**) calloc(args->files->nreaders, sizeof(char*)); + + for (i=0; ifiles->nreaders; i++) + { + if ( args->write && !args->write[i] ) continue; + if ( args->isec_op==OP_COMPLEMENT && i>0 ) break; + OPEN_FILE(i,i); + fprintf(args->fh_log,"%s\tfor stripped\t%s\n", args->fnames[i], args->files->readers[i].fname); + } + #undef OPEN_FILE + + args->fh_sites = open_file(NULL, "w", "%s/sites.txt", args->prefix); + if ( !args->fh_sites ) error("%s/sites.txt: %s\n", args->prefix, strerror(errno)); + } + } + else { + if (args->output_fname) { + args->fh_sites = fopen(args->output_fname, "w"); + if ( args->fh_sites == NULL ) error("Can't write to \"%s\": %s\n", args->output_fname, strerror(errno)); + } + else + args->fh_sites = stdout; + } +} + +static void destroy_data(args_t *args) +{ + int i; + if ( args->nflt ) + { + for (i=0; inflt; i++) + { + if ( !args->flt[i] ) continue; + filter_destroy(args->flt[i]); + } + free(args->flt_expr); + free(args->flt); + free(args->flt_logic); + } + if ( args->prefix ) + { + fclose(args->fh_log); + int n = args->isec_op==OP_VENN ? 4 : args->files->nreaders; + for (i=0; ifnames[i] ) continue; + hts_close(args->fh_out[i]); + if ( args->output_type==FT_VCF_GZ ) + { + tbx_conf_t conf = tbx_conf_vcf; + tbx_index_build(args->fnames[i], -1, &conf); + } + else if ( args->output_type==FT_BCF_GZ ) + { + if ( bcf_index_build(args->fnames[i],14) ) error("Could not index %s\n", args->fnames[i]); + } + free(args->fnames[i]); + } + free(args->fh_out); + free(args->fnames); + if ( args->fh_sites ) fclose(args->fh_sites); + if ( args->write ) free(args->write); + } +} + +static void usage(void) +{ + fprintf(stderr, "\n"); + fprintf(stderr, "About: Create intersections, unions and complements of VCF files.\n"); + fprintf(stderr, "Usage: bcftools isec [options] [...]\n"); + fprintf(stderr, "\n"); + fprintf(stderr, "Options:\n"); + fprintf(stderr, " -c, --collapse treat as identical records with , see man page for details [none]\n"); + fprintf(stderr, " -C, --complement output positions present only in the first file but missing in the others\n"); + fprintf(stderr, " -e, --exclude exclude sites for which the expression is true\n"); + fprintf(stderr, " -f, --apply-filters require at least one of the listed FILTER strings (e.g. \"PASS,.\")\n"); + fprintf(stderr, " -i, --include include only sites for which the expression is true\n"); + fprintf(stderr, " --no-version do not append version and command line to the header\n"); + fprintf(stderr, " -n, --nfiles [+-=~] output positions present in this many (=), this many or more (+), this many or fewer (-), the exact (~) files\n"); + fprintf(stderr, " -o, --output write output to a file [standard output]\n"); + fprintf(stderr, " -O, --output-type b: compressed BCF, u: uncompressed BCF, z: compressed VCF, v: uncompressed VCF [v]\n"); + fprintf(stderr, " -p, --prefix if given, subset each of the input files accordingly, see also -w\n"); + fprintf(stderr, " -r, --regions restrict to comma-separated list of regions\n"); + fprintf(stderr, " -R, --regions-file restrict to regions listed in a file\n"); + fprintf(stderr, " -t, --targets similar to -r but streams rather than index-jumps\n"); + fprintf(stderr, " -T, --targets-file similar to -R but streams rather than index-jumps\n"); + fprintf(stderr, " --threads number of extra output compression threads [0]\n"); + fprintf(stderr, " -w, --write list of files to write with -p given as 1-based indexes. By default, all files are written\n"); + fprintf(stderr, "\n"); + fprintf(stderr, "Examples:\n"); + fprintf(stderr, " # Create intersection and complements of two sets saving the output in dir/*\n"); + fprintf(stderr, " bcftools isec A.vcf.gz B.vcf.gz -p dir\n"); + fprintf(stderr, "\n"); + fprintf(stderr, " # Filter sites in A and B (but not in C) and create intersection\n"); + fprintf(stderr, " bcftools isec -e'MAF<0.01' -i'dbSNP=1' -e - A.vcf.gz B.vcf.gz C.vcf.gz -p dir\n"); + fprintf(stderr, "\n"); + fprintf(stderr, " # Extract and write records from A shared by both A and B using exact allele match\n"); + fprintf(stderr, " bcftools isec A.vcf.gz B.vcf.gz -p dir -n =2 -w 1\n"); + fprintf(stderr, "\n"); + fprintf(stderr, " # Extract records private to A or B comparing by position only\n"); + fprintf(stderr, " bcftools isec A.vcf.gz B.vcf.gz -p dir -n -1 -c all\n"); + fprintf(stderr, "\n"); + exit(1); +} + +int main_vcfisec(int argc, char *argv[]) +{ + int c; + args_t *args = (args_t*) calloc(1,sizeof(args_t)); + args->files = bcf_sr_init(); + args->argc = argc; args->argv = argv; + args->output_fname = NULL; + args->output_type = FT_VCF; + args->n_threads = 0; + args->record_cmd_line = 1; + int targets_is_file = 0, regions_is_file = 0; + + static struct option loptions[] = + { + {"help",no_argument,NULL,'h'}, + {"exclude",required_argument,NULL,'e'}, + {"include",required_argument,NULL,'i'}, + {"collapse",required_argument,NULL,'c'}, + {"complement",no_argument,NULL,'C'}, + {"apply-filters",required_argument,NULL,'f'}, + {"nfiles",required_argument,NULL,'n'}, + {"prefix",required_argument,NULL,'p'}, + {"write",required_argument,NULL,'w'}, + {"targets",required_argument,NULL,'t'}, + {"targets-file",required_argument,NULL,'T'}, + {"regions",required_argument,NULL,'r'}, + {"regions-file",required_argument,NULL,'R'}, + {"output",required_argument,NULL,'o'}, + {"output-type",required_argument,NULL,'O'}, + {"threads",required_argument,NULL,9}, + {"no-version",no_argument,NULL,8}, + {NULL,0,NULL,0} + }; + while ((c = getopt_long(argc, argv, "hc:r:R:p:n:w:t:T:Cf:o:O:i:e:",loptions,NULL)) >= 0) { + switch (c) { + case 'o': args->output_fname = optarg; break; + case 'O': + switch (optarg[0]) { + case 'b': args->output_type = FT_BCF_GZ; break; + case 'u': args->output_type = FT_BCF; break; + case 'z': args->output_type = FT_VCF_GZ; break; + case 'v': args->output_type = FT_VCF; break; + default: error("The output type \"%s\" not recognised\n", optarg); + } + break; + case 'c': + if ( !strcmp(optarg,"snps") ) args->files->collapse |= COLLAPSE_SNPS; + else if ( !strcmp(optarg,"indels") ) args->files->collapse |= COLLAPSE_INDELS; + else if ( !strcmp(optarg,"both") ) args->files->collapse |= COLLAPSE_SNPS | COLLAPSE_INDELS; + else if ( !strcmp(optarg,"any") ) args->files->collapse |= COLLAPSE_ANY; + else if ( !strcmp(optarg,"all") ) args->files->collapse |= COLLAPSE_ANY; + else if ( !strcmp(optarg,"some") ) args->files->collapse |= COLLAPSE_SOME; + else if ( !strcmp(optarg,"none") ) args->files->collapse = COLLAPSE_NONE; + else error("The --collapse string \"%s\" not recognised.\n", optarg); + break; + case 'f': args->files->apply_filters = optarg; break; + case 'C': args->isec_op = OP_COMPLEMENT; break; + case 'r': args->regions_list = optarg; break; + case 'R': args->regions_list = optarg; regions_is_file = 1; break; + case 't': args->targets_list = optarg; break; + case 'T': args->targets_list = optarg; targets_is_file = 1; break; + case 'p': args->prefix = optarg; break; + case 'w': args->write_files = optarg; break; + case 'i': add_filter(args, optarg, FLT_INCLUDE); break; + case 'e': add_filter(args, optarg, FLT_EXCLUDE); break; + case 'n': + { + char *p = optarg; + if ( *p=='-' ) { args->isec_op = OP_MINUS; p++; } + else if ( *p=='+' ) { args->isec_op = OP_PLUS; p++; } + else if ( *p=='=' ) { args->isec_op = OP_EQUAL; p++; } + else if ( *p=='~' ) { args->isec_op = OP_EXACT; p++; } + else if ( isdigit(*p) ) args->isec_op = OP_EQUAL; + else error("Could not parse --nfiles %s\n", optarg); + if ( args->isec_op == OP_EXACT ) args->isec_exact = p; + else if ( sscanf(p,"%d",&args->isec_n)!=1 ) error("Could not parse --nfiles %s\n", optarg); + } + break; + case 9 : args->n_threads = strtol(optarg, 0, 0); break; + case 8 : args->record_cmd_line = 0; break; + case 'h': + case '?': usage(); + default: error("Unknown argument: %s\n", optarg); + } + } + if ( argc-optind<1 ) usage(); // no file given + if ( args->targets_list && bcf_sr_set_targets(args->files, args->targets_list, targets_is_file,0)<0 ) + error("Failed to read the targets: %s\n", args->targets_list); + if ( args->regions_list && bcf_sr_set_regions(args->files, args->regions_list, regions_is_file)<0 ) + error("Failed to read the regions: %s\n", args->regions_list); + if ( argc-optind==2 && !args->isec_op ) + { + args->isec_op = OP_VENN; + if ( !args->prefix ) error("Expected the -p option\n"); + } + if ( !args->targets_list ) + { + if ( argc-optind<2 ) error("Expected multiple files or the --targets option\n"); + if ( !args->isec_op ) error("Expected two file names or one of the options --complement, --nfiles or --targets\n"); + } + args->files->require_index = 1; + while (optindfiles, argv[optind]) ) error("Failed to open %s: %s\n", argv[optind],bcf_sr_strerror(args->files->errnum)); + optind++; + } + init_data(args); + isec_vcf(args); + destroy_data(args); + bcf_sr_destroy(args->files); + free(args); + return 0; +} + diff --git a/vcfmerge.c b/vcfmerge.c new file mode 100644 index 0000000..1aeb739 --- /dev/null +++ b/vcfmerge.c @@ -0,0 +1,2470 @@ +/* vcfmerge.c -- Merge multiple VCF/BCF files to create one multi-sample file. + + Copyright (C) 2012-2016 Genome Research Ltd. + + Author: Petr Danecek + +Permission is hereby granted, free of charge, to any person obtaining a copy +of this software and associated documentation files (the "Software"), to deal +in the Software without restriction, including without limitation the rights +to use, copy, modify, merge, publish, distribute, sublicense, and/or sell +copies of the Software, and to permit persons to whom the Software is +furnished to do so, subject to the following conditions: + +The above copyright notice and this permission notice shall be included in +all copies or substantial portions of the Software. + +THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE +AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER +LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, +OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN +THE SOFTWARE. */ + +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include "bcftools.h" +#include "regidx.h" +#include "vcmp.h" + +#define DBG 0 + +#include +KHASH_MAP_INIT_STR(strdict, int) +typedef khash_t(strdict) strdict_t; + +#define FLT_LOGIC_ADD 0 +#define FLT_LOGIC_REMOVE 1 + +#define SKIP_DONE 1 // the record was processed +#define SKIP_DIFF 2 // not compatible, merge later + +#define IS_VL_G(hdr,id) (bcf_hdr_id2length(hdr,BCF_HL_FMT,id) == BCF_VL_G) +#define IS_VL_A(hdr,id) (bcf_hdr_id2length(hdr,BCF_HL_FMT,id) == BCF_VL_A) +#define IS_VL_R(hdr,id) (bcf_hdr_id2length(hdr,BCF_HL_FMT,id) == BCF_VL_R) + +#define SWAP(type_t,a,b) { type_t tmp = (a); (a) = (b); (b) = tmp; } + +// For merging INFO Number=A,G,R tags +typedef struct +{ + const char *hdr_tag; + int type, nvals; + int nbuf, mbuf; + uint8_t *buf; +} +AGR_info_t; + +// Rules for merging arbitrary INFO tags +typedef struct _info_rule_t +{ + char *hdr_tag; + void (*merger)(bcf_hdr_t *hdr, bcf1_t *line, struct _info_rule_t *rule); + int type; // one of BCF_HT_* + int block_size; // number of values in a block + int type_size; // size of the corresponding BCF_HT_* type + int nblocks; // number of blocks in nvals (the number of merged files) + int nvals, mvals; // used and total size of vals array + void *vals; // the info tag values +} +info_rule_t; + +typedef struct +{ + bcf1_t *line; + int end, active; +} +gvcf_aux_t; + +// Auxiliary merge data for selecting the right combination +// of buffered records across multiple readers. maux1_t +// corresponds to one buffered line. +typedef struct +{ + int skip; + int *map; // mapping from input alleles to the array of output alleles (set by merge_alleles) + int mmap; // size of map array (only buffer[i].n_allele is actually used) + int als_differ; +} +maux1_t; +typedef struct +{ + int rid; // current rid + int beg,end; // valid ranges in reader's buffer [beg,end). Maintained by maux_reset and gvcf_flush. + int cur; // current line or -1 if none + int npos; // number of unprocessed lines at this position + int mrec; // allocated size of buf + maux1_t *rec; // buffer to keep reader's lines + bcf1_t **lines; // source buffer: either gvcf or readers' buffer +} +buffer_t; +typedef struct +{ + int n, pos, var_types; // number of readers, current position, currently available variant types + char *chr; // current chromosome + char **als, **out_als; // merged alleles (temp, may contain empty records) and merged alleles ready for output + int nals, mals, nout_als, mout_als; // size of the output array + int *cnt, ncnt; // number of records that refer to the alleles + int *smpl_ploidy, *smpl_nGsize; // ploidy and derived number of values in Number=G tags, updated for each line (todo: cache for missing cases) + bcf_fmt_t **fmt_map; // i-th output FORMAT field corresponds in j-th reader to i*nreader+j, first row is reserved for GT + int nfmt_map; // number of rows in the fmt_map array + int *agr_map, nagr_map, magr_map; // mapping between Number=AGR element indexes + void *tmp_arr; + int ntmp_arr; + buffer_t *buf; + AGR_info_t *AGR_info; + int nAGR_info, mAGR_info; + bcf_srs_t *files; + int gvcf_min, gvcf_break; // min buffered gvcf END position (NB: gvcf_min is 1-based) or 0 if no active lines are present + gvcf_aux_t *gvcf; // buffer of gVCF lines +} +maux_t; + +typedef struct +{ + vcmp_t *vcmp; + maux_t *maux; + regidx_t *regs; // apply regions only after the blocks are expanded + regitr_t *regs_itr; + int header_only, collapse, output_type, force_samples, merge_by_id, do_gvcf, filter_logic, missing_to_ref; + char *header_fname, *output_fname, *regions_list, *info_rules, *file_list; + faidx_t *gvcf_fai; + info_rule_t *rules; + int nrules; + strdict_t *tmph; + kstring_t tmps; + bcf_srs_t *files; + bcf1_t *out_line; + htsFile *out_fh; + bcf_hdr_t *out_hdr; + char **argv; + int argc, n_threads, record_cmd_line; +} +args_t; + +static bcf1_t *maux_get_line(args_t *args, int i) +{ + maux_t *ma = args->maux; + int ibuf = ma->buf[i].cur; + if ( ibuf >= 0 ) return ma->buf[i].lines[ibuf]; + return NULL; +} + +static void info_rules_merge_sum(bcf_hdr_t *hdr, bcf1_t *line, info_rule_t *rule) +{ + if ( !rule->nvals ) return; + int i, j, ndim = rule->block_size; + #define BRANCH(type_t,is_missing) { \ + type_t *ptr = (type_t*) rule->vals; \ + for (i=0; invals; i++) if ( is_missing ) ptr[i] = 0; \ + for (i=1; inblocks; i++) \ + { \ + for (j=0; jtype) { + case BCF_HT_INT: BRANCH(int32_t, ptr[i]==bcf_int32_missing); break; + case BCF_HT_REAL: BRANCH(float, bcf_float_is_missing(ptr[i])); break; + default: error("TODO: %s:%d .. type=%d\n", __FILE__,__LINE__, rule->type); + } + #undef BRANCH + + bcf_update_info(hdr,line,rule->hdr_tag,rule->vals,ndim,rule->type); +} +static void info_rules_merge_avg(bcf_hdr_t *hdr, bcf1_t *line, info_rule_t *rule) +{ + if ( !rule->nvals ) return; + int i, j, ndim = rule->block_size; + #define BRANCH(type_t,is_missing) { \ + type_t *ptr = (type_t*) rule->vals; \ + for (i=0; invals; i++) if ( is_missing ) ptr[i] = 0; \ + for (j=0; jnblocks; i++) sum += ptr[j+i*ndim]; \ + ptr[j] = sum / rule->nblocks; \ + } \ + } + switch (rule->type) { + case BCF_HT_INT: BRANCH(int32_t, ptr[i]==bcf_int32_missing); break; + case BCF_HT_REAL: BRANCH(float, bcf_float_is_missing(ptr[i])); break; + default: error("TODO: %s:%d .. type=%d\n", __FILE__,__LINE__, rule->type); + } + #undef BRANCH + + bcf_update_info(hdr,line,rule->hdr_tag,rule->vals,ndim,rule->type); +} +static void info_rules_merge_min(bcf_hdr_t *hdr, bcf1_t *line, info_rule_t *rule) +{ + if ( !rule->nvals ) return; + int i, j, ndim = rule->block_size; + #define BRANCH(type_t,is_missing,set_missing,huge_val) { \ + type_t *ptr = (type_t*) rule->vals; \ + for (i=0; invals; i++) if ( is_missing ) ptr[i] = huge_val; \ + for (i=1; inblocks; i++) \ + { \ + for (j=0; j ptr[j+i*ndim] ) ptr[j] = ptr[j+i*ndim]; \ + } \ + for (i=0; invals; i++) if ( ptr[i]==huge_val ) set_missing; \ + } + switch (rule->type) { + case BCF_HT_INT: BRANCH(int32_t, ptr[i]==bcf_int32_missing, ptr[i]=bcf_int32_missing, INT32_MAX); break; + case BCF_HT_REAL: BRANCH(float, bcf_float_is_missing(ptr[i]), bcf_float_set_missing(ptr[i]), HUGE_VAL); break; + default: error("TODO: %s:%d .. type=%d\n", __FILE__,__LINE__, rule->type); + } + #undef BRANCH + + bcf_update_info(hdr,line,rule->hdr_tag,rule->vals,ndim,rule->type); +} +static void info_rules_merge_max(bcf_hdr_t *hdr, bcf1_t *line, info_rule_t *rule) +{ + if ( !rule->nvals ) return; + int i, j, ndim = rule->block_size; + #define BRANCH(type_t,is_missing,set_missing,huge_val) { \ + type_t *ptr = (type_t*) rule->vals; \ + for (i=0; invals; i++) if ( is_missing ) ptr[i] = huge_val; \ + for (i=1; inblocks; i++) \ + { \ + for (j=0; jnvals; i++) if ( ptr[i]==huge_val ) set_missing; \ + } + switch (rule->type) { + case BCF_HT_INT: BRANCH(int32_t, ptr[i]==bcf_int32_missing, ptr[i]=bcf_int32_missing, INT32_MIN); break; + case BCF_HT_REAL: BRANCH(float, bcf_float_is_missing(ptr[i]), bcf_float_set_missing(ptr[i]), -HUGE_VAL); break; + default: error("TODO: %s:%d .. type=%d\n", __FILE__,__LINE__, rule->type); + } + #undef BRANCH + + bcf_update_info(hdr,line,rule->hdr_tag,rule->vals,ndim,rule->type); +} +static void info_rules_merge_join(bcf_hdr_t *hdr, bcf1_t *line, info_rule_t *rule) +{ + if ( !rule->nvals ) return; + if ( rule->type==BCF_HT_STR ) + { + ((char*)rule->vals)[rule->nvals] = 0; + bcf_update_info_string(hdr,line,rule->hdr_tag,rule->vals); + } + else + bcf_update_info(hdr,line,rule->hdr_tag,rule->vals,rule->nvals,rule->type); +} + +static int info_rules_comp_key2(const void *a, const void *b) +{ + info_rule_t *rule1 = (info_rule_t*) a; + info_rule_t *rule2 = (info_rule_t*) b; + return strcmp(rule1->hdr_tag, rule2->hdr_tag); +} +static int info_rules_comp_key(const void *a, const void *b) +{ + char *key = (char*) a; + info_rule_t *rule = (info_rule_t*) b; + return strcmp(key, rule->hdr_tag); +} +static void info_rules_init(args_t *args) +{ + if ( args->info_rules && !strcmp("-",args->info_rules) ) return; + + kstring_t str = {0,0,0}; + if ( !args->info_rules ) + { + if ( bcf_hdr_idinfo_exists(args->out_hdr,BCF_HL_INFO,bcf_hdr_id2int(args->out_hdr, BCF_DT_ID, "DP")) ) kputs("DP:sum",&str); + if ( bcf_hdr_idinfo_exists(args->out_hdr,BCF_HL_INFO,bcf_hdr_id2int(args->out_hdr, BCF_DT_ID, "DP4")) ) + { + if ( str.l ) kputc(',',&str); + kputs("DP4:sum",&str); + } + if ( args->do_gvcf && bcf_hdr_idinfo_exists(args->out_hdr,BCF_HL_INFO,bcf_hdr_id2int(args->out_hdr, BCF_DT_ID, "QS")) ) + { + if ( str.l ) kputc(',',&str); + kputs("QS:sum",&str); + } + if ( args->do_gvcf && bcf_hdr_idinfo_exists(args->out_hdr,BCF_HL_INFO,bcf_hdr_id2int(args->out_hdr, BCF_DT_ID, "MinDP")) ) + { + if ( str.l ) kputc(',',&str); + kputs("MinDP:min",&str); + } + if ( args->do_gvcf && bcf_hdr_idinfo_exists(args->out_hdr,BCF_HL_INFO,bcf_hdr_id2int(args->out_hdr, BCF_DT_ID, "I16")) ) + { + if ( str.l ) kputc(',',&str); + kputs("I16:sum",&str); + } + if ( args->do_gvcf && bcf_hdr_idinfo_exists(args->out_hdr,BCF_HL_INFO,bcf_hdr_id2int(args->out_hdr, BCF_DT_ID, "IDV")) ) + { + if ( str.l ) kputc(',',&str); + kputs("IDV:max",&str); + } + if ( args->do_gvcf && bcf_hdr_idinfo_exists(args->out_hdr,BCF_HL_INFO,bcf_hdr_id2int(args->out_hdr, BCF_DT_ID, "IMF")) ) + { + if ( str.l ) kputc(',',&str); + kputs("IMF:max",&str); + } + + if ( !str.l ) return; + args->info_rules = str.s; + } + + args->nrules = 1; + char *ss = strdup(args->info_rules), *tmp = ss; + int n = 0; + while ( *ss ) + { + if ( *ss==':' ) { *ss = 0; n++; if ( n%2==0 ) error("Could not parse INFO rules: \"%s\"\n", args->info_rules); } + else if ( *ss==',' ) { *ss = 0; args->nrules++; n++; if ( n%2==1 ) error("Could not parse INFO rules: \"%s\"\n", args->info_rules); } + ss++; + } + if ( n%2==0 ) error("Could not parse INFO rules: \"%s\"\n", args->info_rules); + args->rules = (info_rule_t*) calloc(args->nrules,sizeof(info_rule_t)); + + n = 0; + ss = tmp; + while ( n < args->nrules ) + { + info_rule_t *rule = &args->rules[n]; + rule->hdr_tag = strdup(ss); + int id = bcf_hdr_id2int(args->out_hdr, BCF_DT_ID, rule->hdr_tag); + if ( !bcf_hdr_idinfo_exists(args->out_hdr,BCF_HL_INFO,id) ) error("The tag is not defined in the header: \"%s\"\n", rule->hdr_tag); + rule->type = bcf_hdr_id2type(args->out_hdr,BCF_HL_INFO,id); + if ( rule->type==BCF_HT_INT ) rule->type_size = sizeof(int32_t); + else if ( rule->type==BCF_HT_REAL ) rule->type_size = sizeof(float); + else if ( rule->type==BCF_HT_STR ) rule->type_size = sizeof(char); + else error("The type is not supported: \"%s\"\n", rule->hdr_tag); + + ss = strchr(ss, '\0'); ss++; + if ( !*ss ) error("Could not parse INFO rules, missing logic of \"%s\"\n", rule->hdr_tag); + + int is_join = 0; + if ( !strcasecmp(ss,"sum") ) rule->merger = info_rules_merge_sum; + else if ( !strcasecmp(ss,"avg") ) rule->merger = info_rules_merge_avg; + else if ( !strcasecmp(ss,"min") ) rule->merger = info_rules_merge_min; + else if ( !strcasecmp(ss,"max") ) rule->merger = info_rules_merge_max; + else if ( !strcasecmp(ss,"join") ) { rule->merger = info_rules_merge_join; is_join = 1; } + else error("The rule logic \"%s\" not recognised\n", ss); + + if ( !is_join && rule->type==BCF_HT_STR ) + error("Numeric operation \"%s\" requested on non-numeric field: %s\n", ss, rule->hdr_tag); + if ( bcf_hdr_id2number(args->out_hdr,BCF_HL_INFO,id)==0xfffff ) + { + int is_agr = ( + bcf_hdr_id2length(args->out_hdr,BCF_HL_INFO,id)==BCF_VL_A || + bcf_hdr_id2length(args->out_hdr,BCF_HL_INFO,id)==BCF_VL_G || + bcf_hdr_id2length(args->out_hdr,BCF_HL_INFO,id)==BCF_VL_R + ) ? 1 : 0; + if ( is_join && is_agr ) + error("Cannot -i %s:join on Number=[AGR] tags is not supported.\n", rule->hdr_tag); + if ( !is_join && !is_agr ) + error("Only fixed-length vectors are supported with -i %s:%s\n", ss, rule->hdr_tag); + } + + ss = strchr(ss, '\0'); ss++; + n++; + } + free(str.s); + free(tmp); + + qsort(args->rules, args->nrules, sizeof(*args->rules), info_rules_comp_key2); +} +static void info_rules_destroy(args_t *args) +{ + int i; + for (i=0; inrules; i++) + { + info_rule_t *rule = &args->rules[i]; + free(rule->hdr_tag); + free(rule->vals); + } + free(args->rules); +} +static void info_rules_reset(args_t *args) +{ + int i; + for (i=0; inrules; i++) + args->rules[i].nblocks = args->rules[i].nvals = args->rules[i].block_size = 0; +} +static int info_rules_add_values(args_t *args, bcf_hdr_t *hdr, bcf1_t *line, info_rule_t *rule, maux1_t *als, int var_len) +{ + int msize = args->maux->ntmp_arr / rule->type_size; + int ret = bcf_get_info_values(hdr, line, rule->hdr_tag, &args->maux->tmp_arr, &msize, rule->type); + if ( ret<=0 ) error("FIXME: error parsing %s at %s:%d .. %d\n", rule->hdr_tag,bcf_seqname(hdr,line),line->pos+1,ret); + args->maux->ntmp_arr = msize * rule->type_size; + + rule->nblocks++; + + if ( rule->type==BCF_HT_STR ) + { + int need_comma = rule->nblocks==1 ? 0 : 1; + hts_expand(char,rule->nvals+ret+need_comma+1,rule->mvals,rule->vals); // 1 for null-termination + char *tmp = (char*) rule->vals + rule->nvals; + if ( rule->nvals>0 ) { *tmp = ','; tmp++; } + strncpy(tmp,(char*)args->maux->tmp_arr,ret); + rule->nvals += ret + need_comma; + return 1; + } + + int i, j; + if ( var_len==BCF_VL_A ) + { + if ( ret!=line->n_allele-1 ) error("Wrong number of %s fields at %s:%d\n",rule->hdr_tag,bcf_seqname(hdr,line),line->pos+1); + args->maux->nagr_map = ret; + hts_expand(int,args->maux->nagr_map,args->maux->magr_map,args->maux->agr_map); + // create mapping from source file ALT indexes to dst file indexes + for (i=0; imaux->agr_map[i] = als->map[i+1] - 1; + rule->block_size = args->maux->nout_als - 1; + } + else if ( var_len==BCF_VL_R ) + { + if ( ret!=line->n_allele ) error("Wrong number of %s fields at %s:%d\n",rule->hdr_tag,bcf_seqname(hdr,line),line->pos+1); + args->maux->nagr_map = ret; + hts_expand(int,args->maux->nagr_map,args->maux->magr_map,args->maux->agr_map); + for (i=0; imaux->agr_map[i] = als->map[i]; + rule->block_size = args->maux->nout_als; + } + else if ( var_len==BCF_VL_G ) + { + args->maux->nagr_map = bcf_alleles2gt(line->n_allele-1,line->n_allele-1)+1; + assert( ret==line->n_allele || ret==args->maux->nagr_map ); + if ( ret==line->n_allele ) // haploid + { + args->maux->nagr_map = line->n_allele; + hts_expand(int,args->maux->nagr_map,args->maux->magr_map,args->maux->agr_map); + for (i=0; imaux->agr_map[i] = als->map[i]; + rule->block_size = args->maux->nout_als; + } + else + { + hts_expand(int,args->maux->nagr_map,args->maux->magr_map,args->maux->agr_map); + int k_src = 0; + for (i=0; in_allele; i++) + { + for (j=0; j<=i; j++) + { + args->maux->agr_map[k_src] = bcf_alleles2gt(als->map[i],als->map[j]); + k_src++; + } + } + rule->block_size = bcf_alleles2gt(args->maux->nout_als-1,args->maux->nout_als-1)+1; + } + } + else + { + if ( rule->nblocks>1 && ret!=rule->block_size ) + error("Mismatch in number of values for INFO/%s at %s:%d\n", rule->hdr_tag,bcf_seqname(hdr,line),line->pos+1); + rule->block_size = ret; + args->maux->nagr_map = 0; + } + + #define BRANCH(src_type_t,dst_type_t,set_missing) { \ + src_type_t *src = (src_type_t *) args->maux->tmp_arr; \ + hts_expand0(dst_type_t,(rule->nvals+rule->block_size),rule->mvals,rule->vals); \ + dst_type_t *dst = (dst_type_t *) rule->vals + rule->nvals; \ + rule->nvals += rule->block_size; \ + if ( !args->maux->nagr_map ) \ + { \ + for (i=0; iblock_size; i++) set_missing; \ + for (i=0; imaux->agr_map[i]] = src[i]; \ + } \ + } + switch (rule->type) { + case BCF_HT_INT: BRANCH(int, int32_t, dst[i] = bcf_int32_missing); break; + case BCF_HT_REAL: BRANCH(float, float, bcf_float_set_missing(dst[i])); break; + default: error("TODO: %s:%d .. type=%d\n", __FILE__,__LINE__, rule->type); + } + #undef BRANCH + + return 1; +} + +int bcf_hdr_sync(bcf_hdr_t *h); + +void merge_headers(bcf_hdr_t *hw, const bcf_hdr_t *hr, const char *clash_prefix, int force_samples) +{ + // header lines + hw = bcf_hdr_merge(hw, hr); + + // samples + int i; + for (i=0; isamples[i]; + if ( bcf_hdr_id2int(hw, BCF_DT_SAMPLE, name)!=-1 ) + { + // there is a sample with the same name + if ( !force_samples ) error("Error: Duplicate sample names (%s), use --force-samples to proceed anyway.\n", name); + + int len = strlen(hr->samples[i]) + strlen(clash_prefix) + 1; + name = (char*) malloc(sizeof(char)*(len+1)); + sprintf(name,"%s:%s",clash_prefix,hr->samples[i]); + bcf_hdr_add_sample(hw,name); + free(name); + } + else + bcf_hdr_add_sample(hw,name); + } +} + +void debug_als(char **als, int nals) +{ + int k; for (k=0; k=lens[j] ) done = 1; + if ( als[j][lens[j]-i] != als[0][lens[0]-i] ) { done = 1; break; } + } + if ( done ) break; + i++; + } + if ( i>1 ) + { + i--; + als[0][lens[0]-i] = 0; + for (j=1; j0, + * 1->2, and 2->3. + */ +char **merge_alleles(char **a, int na, int *map, char **b, int *nb, int *mb) +{ + // reference allele never changes + map[0] = 0; + + int i,j; + int rla = !a[0][1] ? 1 : strlen(a[0]); + int rlb = !b[0][1] ? 1 : strlen(b[0]); + + // the most common case: same SNPs + if ( na==2 && *nb==2 && rla==1 && rlb==1 && a[1][0]==b[1][0] && !a[1][1] && !b[1][1] ) + { + map[1] = 1; + return b; + } + + // Sanity check: reference prefixes must be identical + if ( strncmp(a[0],b[0],rlarlb ) + { + for (i=0; i<*nb; i++) + { + if ( b[i][0]=='<' ) continue; // symbolic allele, do not modify + if ( b[i][0]=='*' ) continue; // overlapping deletion (*), do not modify + int l = strlen(b[i]); + b[i] = (char*) realloc(b[i],l+rla-rlb+1); + memcpy(b[i]+l,a[0]+rlb,rla-rlb+1); + } + } + + // now check if the $a alleles are present and if not add them + for (i=1; irla && a[i][0]!='<' && a[i][0]!='*' ) // $a alleles need expanding and not a symbolic allele or * + { + int l = strlen(a[i]); + ai = (char*) malloc(l+rlb-rla+1); + memcpy(ai,a[i],l); + memcpy(ai+l,b[0]+rla,rlb-rla+1); + const_ai = 0; + } + else + ai = a[i]; + + for (j=1; j<*nb; j++) + if ( !strcasecmp(ai,b[j]) ) break; + + if ( j<*nb ) // $b already has the same allele + { + map[i] = j; + if ( !const_ai ) free(ai); + continue; + } + // new allele + map[i] = *nb; + if ( b[*nb] ) free(b[*nb]); + b[*nb] = const_ai ? strdup(ai) : ai; + (*nb)++; + } + return b; +} + +maux_t *maux_init(args_t *args) +{ + bcf_srs_t *files = args->files; + maux_t *ma = (maux_t*) calloc(1,sizeof(maux_t)); + ma->n = files->nreaders; + ma->files = files; + int i, n_smpl = 0; + for (i=0; in; i++) + n_smpl += bcf_hdr_nsamples(files->readers[i].header); + if ( args->do_gvcf ) + { + ma->gvcf = (gvcf_aux_t*) calloc(ma->n,sizeof(gvcf_aux_t)); + for (i=0; in; i++) + ma->gvcf[i].line = bcf_init1(); + } + ma->smpl_ploidy = (int*) calloc(n_smpl,sizeof(int)); + ma->smpl_nGsize = (int*) malloc(n_smpl*sizeof(int)); + ma->buf = (buffer_t*) calloc(ma->n,sizeof(buffer_t)); + for (i=0; in; i++) + ma->buf[i].rid = -1; + return ma; +} +void maux_destroy(maux_t *ma) +{ + int i,j; + for (i=0; imals; i++) + { + free(ma->als[i]); + ma->als[i] = NULL; + } + for (i=0; in; i++) // for each reader + { + for (j=0; jbuf[i].mrec; j++) // for each buffered line + free(ma->buf[i].rec[j].map); + free(ma->buf[i].rec); + } + free(ma->buf); + if ( ma->gvcf ) + { + for (i=0; in; i++) bcf_destroy(ma->gvcf[i].line); + free(ma->gvcf); + } + for (i=0; imAGR_info; i++) + free(ma->AGR_info[i].buf); + free(ma->agr_map); + free(ma->AGR_info); + if (ma->ntmp_arr) free(ma->tmp_arr); + if (ma->nfmt_map) free(ma->fmt_map); + // ma->inf freed in bcf_destroy1 + for (i=0; imals; i++) free(ma->als[i]); + if (ma->mout_als) free(ma->out_als); + free(ma->als); + free(ma->cnt); + free(ma->smpl_ploidy); + free(ma->smpl_nGsize); + free(ma->chr); + free(ma); +} +void maux_expand1(buffer_t *buf, int size) +{ + if ( buf->mrec < size ) + { + hts_expand0(maux1_t,size,buf->mrec,buf->rec); + buf->mrec = size; + } +} +void maux_reset(maux_t *ma) +{ + int i,j; + for (i=0; in; i++) maux_expand1(&ma->buf[i],ma->files->readers[i].nbuffer+1); + for (i=0; incnt; i++) ma->cnt[i] = 0; + for (i=0; imals; i++) + { + free(ma->als[i]); + ma->als[i] = NULL; + } + const char *chr = NULL; + ma->nals = 0; + ma->pos = -1; + for (i=0; in; i++) + { + if ( !bcf_sr_has_line(ma->files,i) ) continue; + bcf1_t *line = bcf_sr_get_line(ma->files,i); + bcf_hdr_t *hdr = bcf_sr_get_header(ma->files,i); + chr = bcf_seqname(hdr,line); + ma->pos = line->pos; + break; + } + if ( chr ) + { + free(ma->chr); + ma->chr = strdup(chr); + } + for (i=0; in; i++) + { + bcf_hdr_t *hdr = bcf_sr_get_header(ma->files,i); + ma->buf[i].rid = bcf_hdr_name2id(hdr,chr); + ma->buf[i].beg = bcf_sr_has_line(ma->files,i) ? 0 : 1; + for (j=ma->buf[i].beg; j<=ma->files->readers[i].nbuffer; j++) + { + ma->buf[i].rec[j].skip = 0; + bcf1_t *line = ma->files->readers[i].buffer[j]; + if ( line->rid!=ma->buf[i].rid || line->pos!=ma->pos ) break; + } + ma->buf[i].end = j; + ma->buf[i].cur = -1; + if ( ma->buf[i].beg < ma->buf[i].end ) + { + ma->buf[i].lines = ma->files->readers[i].buffer; + if ( ma->gvcf ) ma->gvcf[i].active = 0; // gvcf block cannot overlap with the next record + } + } +} +void maux_debug(maux_t *ma, int ir, int ib) +{ + printf("[%d,%d]\t", ir,ib); + int i; + for (i=0; inals; i++) + { + printf(" %s [%d]", ma->als[i], ma->cnt[i]); + } + printf("\n"); +} + +void merge_chrom2qual(args_t *args, bcf1_t *out) +{ + bcf_srs_t *files = args->files; + bcf_hdr_t *out_hdr = args->out_hdr; + + int i, ret; + khiter_t kitr; + strdict_t *tmph = args->tmph; + kh_clear(strdict, tmph); + kstring_t *tmps = &args->tmps; + tmps->l = 0; + + maux_t *ma = args->maux; + int *al_idxs = (int*) calloc(ma->nals,sizeof(int)); + bcf_float_set_missing(out->qual); + + // CHROM, POS, ID, QUAL + out->pos = -1; + for (i=0; inreaders; i++) + { + bcf1_t *line = maux_get_line(args, i); + if ( !line ) continue; + bcf_unpack(line, BCF_UN_ALL); + + bcf_sr_t *reader = &files->readers[i]; + bcf_hdr_t *hdr = reader->header; + + // not all maux alleles are always used, mark the ones we'll need + int j; + for (j=1; jn_allele; j++) + { + int irec = ma->buf[i].cur; + al_idxs[ ma->buf[i].rec[irec].map[j] ] = 1; + } + + // position + if ( out->pos==-1 ) + { + const char *chr = hdr->id[BCF_DT_CTG][line->rid].key; + out->rid = bcf_hdr_name2id(out_hdr, chr); + if ( strcmp(chr,out_hdr->id[BCF_DT_CTG][out->rid].key) ) error("Uh\n"); + out->pos = line->pos; + } + + // ID + if ( line->d.id[0]!='.' || line->d.id[1] ) + { + kitr = kh_get(strdict, tmph, line->d.id); + if ( kitr == kh_end(tmph) ) + { + if ( tmps->l ) kputc(';', tmps); + kputs(line->d.id, tmps); + kh_put(strdict, tmph, line->d.id, &ret); + } + } + + // set QUAL to the max qual value. Not exactly correct, but good enough for now + if ( !bcf_float_is_missing(line->qual) ) + { + if ( bcf_float_is_missing(out->qual) || out->qual < line->qual ) out->qual = line->qual; + } + } + + // set ID + if ( !tmps->l ) kputs(".", tmps); + bcf_update_id(out_hdr, out, tmps->s); + + // set alleles + ma->nout_als = 0; + for (i=1; inals; i++) + { + if ( !al_idxs[i] ) continue; + ma->nout_als++; + + // Adjust the indexes, the allele map could be created for multiple collapsed records, + // some of which might be unused for this output line + int ir, j; + for (ir=0; irnreaders; ir++) + { + bcf1_t *line = maux_get_line(args,ir); + if ( !line ) continue; + for (j=1; jn_allele; j++) + { + int irec = ma->buf[ir].cur; + if ( ma->buf[ir].rec[irec].map[j]==i ) ma->buf[ir].rec[irec].map[j] = ma->nout_als; + } + } + } + // Expand the arrays and realloc the alleles string. Note that all alleles are in a single allocated block. + ma->nout_als++; + hts_expand0(char*, ma->nout_als, ma->mout_als, ma->out_als); + int k = 0; + for (i=0; inals; i++) + if ( i==0 || al_idxs[i] ) ma->out_als[k++] = strdup(ma->als[i]); + assert( k==ma->nout_als ); + normalize_alleles(ma->out_als, ma->nout_als); + bcf_update_alleles(out_hdr, out, (const char**) ma->out_als, ma->nout_als); + free(al_idxs); + for (i=0; inout_als; i++) free(ma->out_als[i]); +} + +void merge_filter(args_t *args, bcf1_t *out) +{ + bcf_srs_t *files = args->files; + bcf_hdr_t *out_hdr = args->out_hdr; + + int i, ret; + if ( args->filter_logic == FLT_LOGIC_REMOVE ) + { + for (i=0; inreaders; i++) + { + bcf1_t *line = maux_get_line(args, i); + if ( !line ) continue; + bcf_sr_t *reader = &files->readers[i]; + bcf_hdr_t *hdr = reader->header; + if ( bcf_has_filter(hdr, line, "PASS") ) break; + } + if ( inreaders ) + { + int flt_id = bcf_hdr_id2int(out_hdr, BCF_DT_ID, "PASS"); + bcf_add_filter(out_hdr, out, flt_id); + return; + } + } + + khiter_t kitr; + strdict_t *tmph = args->tmph; + kh_clear(strdict, tmph); + + out->d.n_flt = 0; + for (i=0; inreaders; i++) + { + bcf1_t *line = maux_get_line(args, i); + if ( !line ) continue; + + bcf_sr_t *reader = &files->readers[i]; + bcf_hdr_t *hdr = reader->header; + + int k; + for (k=0; kd.n_flt; k++) + { + const char *flt = hdr->id[BCF_DT_ID][line->d.flt[k]].key; + kitr = kh_get(strdict, tmph, flt); + if ( kitr == kh_end(tmph) ) + { + int id = bcf_hdr_id2int(out_hdr, BCF_DT_ID, flt); + if ( id==-1 ) error("Error: The filter is not defined in the header: %s\n", flt); + hts_expand(int,out->d.n_flt+1,out->d.m_flt,out->d.flt); + out->d.flt[out->d.n_flt] = id; + out->d.n_flt++; + kh_put(strdict, tmph, flt, &ret); + } + } + } + // Check if PASS is not mixed with other filters + if ( out->d.n_flt>1 ) + { + int id = bcf_hdr_id2int(out_hdr, BCF_DT_ID, "PASS"); + for (i=0; id.n_flt; i++) + if ( out->d.flt[i]==id ) break; + if ( id.n_flt ) + { + out->d.n_flt--; + for (; id.n_flt; i++) out->d.flt[i] = out->d.flt[i+1]; + } + } +} + +static void bcf_info_set_id(bcf1_t *line, bcf_info_t *info, int id, kstring_t *tmp_str) +{ + uint8_t *ptr = info->vptr - info->vptr_off; + bcf_dec_typed_int1(ptr, &ptr); + + tmp_str->l = 0; + bcf_enc_int1(tmp_str, id); + + if ( tmp_str->l == ptr - info->vptr + info->vptr_off ) + { + // the new id is represented with the same number of bytes + memcpy(info->vptr - info->vptr_off, tmp_str->s, tmp_str->l); + return; + } + + kputsn_(ptr, info->vptr - ptr, tmp_str); + info->vptr_off = tmp_str->l; + kputsn_(info->vptr, info->len << bcf_type_shift[info->type], tmp_str); + + info->vptr = (uint8_t*) tmp_str->s + info->vptr_off; + tmp_str->s = NULL; + tmp_str->m = 0; + tmp_str->l = 0; +} + +/* + * copy_string_field() - copy a comma-separated field + * @param src: source string + * @param isrc: index of the field to copy + * @param src_len: length of source string (excluding the terminating \0) + * @param dst: destination kstring (must be initialized) + * @param idst: index of the destination field + */ +int copy_string_field(char *src, int isrc, int src_len, kstring_t *dst, int idst) +{ + int ith_src = 0, start_src = 0; // i-th field in src string + while ( ith_srcl ) + { + if ( dst->s[start_dst]==',' ) { ith_dst++; } + start_dst++; + } + if ( ith_dst!=idst ) return -2; + int end_dst = start_dst; + while ( end_dstl && dst->s[end_dst]!=',' ) end_dst++; + + if ( end_dst - start_dst>1 || dst->s[start_dst]!='.' ) return 0; // do not overwrite non-empty values + + // Now start_dst and end_dst are indexes to the destination memory area + // which needs to be replaced with nsrc_cpy + // source bytes, end_dst points just after. + int ndst_shift = nsrc_cpy - (end_dst - start_dst); + int ndst_move = dst->l - end_dst + 1; // how many bytes must be moved (including \0) + if ( ndst_shift ) + { + ks_resize(dst, dst->l + ndst_shift + 1); // plus \0 + memmove(dst->s+end_dst+ndst_shift, dst->s+end_dst, ndst_move); + } + memcpy(dst->s+start_dst, src+start_src, nsrc_cpy); + dst->l += ndst_shift; + return 0; +} + +static void merge_AGR_info_tag(bcf_hdr_t *hdr, bcf1_t *line, bcf_info_t *info, int len, maux1_t *als, AGR_info_t *agr) +{ + int i; + if ( !agr->nbuf ) + { + if ( info->type==BCF_BT_INT8 || info->type==BCF_BT_INT16 || info->type==BCF_BT_INT32 || info->type==BCF_BT_FLOAT ) + { + agr->nbuf = 4 * agr->nvals; + hts_expand(uint8_t,agr->nbuf,agr->mbuf,agr->buf); + if ( info->type!=BCF_BT_FLOAT ) + { + int32_t *tmp = (int32_t*) agr->buf; + for (i=0; invals; i++) tmp[i] = bcf_int32_missing; + } + else + { + float *tmp = (float*) agr->buf; + for (i=0; invals; i++) bcf_float_set_missing(tmp[i]); + } + } + else if ( info->type==BCF_BT_CHAR ) + { + kstring_t tmp; tmp.l = 0; tmp.m = agr->mbuf; tmp.s = (char*)agr->buf; + kputc('.',&tmp); + for (i=1; invals; i++) kputs(",.",&tmp); + agr->mbuf = tmp.m; agr->nbuf = tmp.l; agr->buf = (uint8_t*)tmp.s; + } + else + error("Not ready for type [%d]: %s at %d\n", info->type,agr->hdr_tag,line->pos+1); + } + + if ( info->type==BCF_BT_INT8 || info->type==BCF_BT_INT16 || info->type==BCF_BT_INT32 || info->type==BCF_BT_FLOAT ) + { + if ( len==BCF_VL_A || len==BCF_VL_R ) + { + int ifrom = len==BCF_VL_A ? 1 : 0; + #define BRANCH(type_t, is_missing, is_vector_end, out_type_t) { \ + type_t *src = (type_t *) info->vptr; \ + out_type_t *tgt = (out_type_t *) agr->buf; \ + int iori, inew; \ + for (iori=ifrom; iorin_allele; iori++) \ + { \ + if ( is_vector_end ) break; \ + if ( is_missing ) continue; \ + inew = als->map[iori] - ifrom; \ + tgt[inew] = *src; \ + src++; \ + } \ + } + switch (info->type) { + case BCF_BT_INT8: BRANCH(int8_t, *src==bcf_int8_missing, *src==bcf_int8_vector_end, int); break; + case BCF_BT_INT16: BRANCH(int16_t, *src==bcf_int16_missing, *src==bcf_int16_vector_end, int); break; + case BCF_BT_INT32: BRANCH(int32_t, *src==bcf_int32_missing, *src==bcf_int32_vector_end, int); break; + case BCF_BT_FLOAT: BRANCH(float, bcf_float_is_missing(*src), bcf_float_is_vector_end(*src), float); break; + default: fprintf(stderr,"TODO: %s:%d .. info->type=%d\n", __FILE__,__LINE__, info->type); exit(1); + } + #undef BRANCH + } + else + { + #define BRANCH(type_t, is_missing, is_vector_end, out_type_t) { \ + type_t *src = (type_t *) info->vptr; \ + out_type_t *tgt = (out_type_t *) agr->buf; \ + int iori,jori, inew,jnew; \ + for (iori=0; iorin_allele; iori++) \ + { \ + inew = als->map[iori]; \ + for (jori=0; jori<=iori; jori++) \ + { \ + jnew = als->map[jori]; \ + int kori = iori*(iori+1)/2 + jori; \ + if ( is_vector_end ) break; \ + if ( is_missing ) continue; \ + int knew = inew>jnew ? inew*(inew+1)/2 + jnew : jnew*(jnew+1)/2 + inew; \ + tgt[knew] = src[kori]; \ + } \ + if ( jori<=iori ) break; \ + } \ + } + switch (info->type) { + case BCF_BT_INT8: BRANCH(int8_t, src[kori]==bcf_int8_missing, src[kori]==bcf_int8_vector_end, int); break; + case BCF_BT_INT16: BRANCH(int16_t, src[kori]==bcf_int16_missing, src[kori]==bcf_int16_vector_end, int); break; + case BCF_BT_INT32: BRANCH(int32_t, src[kori]==bcf_int32_missing, src[kori]==bcf_int32_vector_end, int); break; + case BCF_BT_FLOAT: BRANCH(float, bcf_float_is_missing(src[kori]), bcf_float_is_vector_end(src[kori]), float); break; + default: fprintf(stderr,"TODO: %s:%d .. info->type=%d\n", __FILE__,__LINE__, info->type); exit(1); + } + #undef BRANCH + } + } + else + { + kstring_t tmp; tmp.l = agr->nbuf; tmp.m = agr->mbuf; tmp.s = (char*)agr->buf; + if ( len==BCF_VL_A || len==BCF_VL_R ) + { + int iori, ifrom = len==BCF_VL_A ? 1 : 0; + for (iori=ifrom; iorin_allele; iori++) + { + int ret = copy_string_field((char*)info->vptr, iori-ifrom, info->len, &tmp, als->map[iori]-ifrom); + if ( ret ) + error("Error at %s:%d: wrong number of fields in %s?\n", bcf_seqname(hdr,line),line->pos+1,agr->hdr_tag); + } + } + else + { + int iori,jori, inew,jnew; + for (iori=0; iorin_allele; iori++) + { + inew = als->map[iori]; + for (jori=0; jori<=iori; jori++) + { + jnew = als->map[jori]; + int kori = iori*(iori+1)/2 + jori; + int knew = bcf_alleles2gt(inew,jnew); + int ret = copy_string_field((char*)info->vptr, kori, info->len, &tmp, knew); + if ( ret ) + error("Error at %s:%d: wrong number of fields in %s?\n", bcf_seqname(hdr,line),line->pos+1,agr->hdr_tag); + } + } + } + agr->mbuf = tmp.m; agr->nbuf = tmp.l; agr->buf = (uint8_t*)tmp.s; + } +} + +void merge_info(args_t *args, bcf1_t *out) +{ + bcf_srs_t *files = args->files; + bcf_hdr_t *out_hdr = args->out_hdr; + + int i, j, ret; + khiter_t kitr; + strdict_t *tmph = args->tmph; + kh_clear(strdict, tmph); + + maux_t *ma = args->maux; + ma->nAGR_info = 0; + out->n_info = 0; + info_rules_reset(args); + for (i=0; inreaders; i++) + { + bcf1_t *line = maux_get_line(args,i); + if ( !line ) continue; + int irec = ma->buf[i].cur; + bcf_sr_t *reader = &files->readers[i]; + bcf_hdr_t *hdr = reader->header; + for (j=0; jn_info; j++) + { + bcf_info_t *inf = &line->d.info[j]; + + const char *key = hdr->id[BCF_DT_ID][inf->key].key; + if ( !strcmp("AC",key) || !strcmp("AN",key) ) continue; // AC and AN are done in merge_format() after genotypes are done + + int id = bcf_hdr_id2int(out_hdr, BCF_DT_ID, key); + if ( id==-1 ) error("Error: The INFO field is not defined in the header: %s\n", key); + + kitr = kh_get(strdict, tmph, key); // have we seen the tag in one of the readers? + int len = bcf_hdr_id2length(hdr,BCF_HL_INFO,inf->key); + if ( args->nrules ) + { + info_rule_t *rule = (info_rule_t*) bsearch(key, args->rules, args->nrules, sizeof(*args->rules), info_rules_comp_key); + if ( rule ) + { + maux1_t *als = ( len==BCF_VL_A || len==BCF_VL_G || len==BCF_VL_R ) ? &ma->buf[i].rec[irec] : NULL; + if ( info_rules_add_values(args, hdr, line, rule, als, len) ) continue; + } + } + + // Todo: Number=AGR tags should use the newer info_rules_* functions (info_rules_merge_first to be added) + // and merge_AGR_info_tag to be made obsolete. + if ( len==BCF_VL_A || len==BCF_VL_G || len==BCF_VL_R ) // Number=R,G,A requires special treatment + { + if ( kitr == kh_end(tmph) ) + { + // seeing this key for the first time + ma->nAGR_info++; + hts_expand0(AGR_info_t,ma->nAGR_info,ma->mAGR_info,ma->AGR_info); + kitr = kh_put(strdict, tmph, key, &ret); + kh_val(tmph,kitr) = ma->nAGR_info - 1; + ma->AGR_info[ma->nAGR_info-1].hdr_tag = key; + ma->AGR_info[ma->nAGR_info-1].type = bcf_hdr_id2type(hdr,BCF_HL_INFO,inf->key); + ma->AGR_info[ma->nAGR_info-1].nbuf = 0; // size of the buffer + switch (len) + { + case BCF_VL_A: ma->AGR_info[ma->nAGR_info-1].nvals = ma->nout_als - 1; break; + case BCF_VL_G: ma->AGR_info[ma->nAGR_info-1].nvals = bcf_alleles2gt(ma->nout_als-1,ma->nout_als-1)+1; break; + case BCF_VL_R: ma->AGR_info[ma->nAGR_info-1].nvals = ma->nout_als; break; + } + } + kitr = kh_get(strdict, tmph, key); + int idx = kh_val(tmph, kitr); + if ( idx<0 ) error("Error occurred while processing INFO tag \"%s\" at %s:%d\n", key,bcf_seqname(hdr,line),line->pos+1); + merge_AGR_info_tag(hdr, line,inf,len,&ma->buf[i].rec[irec],&ma->AGR_info[idx]); + continue; + } + + if ( kitr == kh_end(tmph) ) + { + // Seeing this key for the first time. Although quite hacky, + // this is faster than anything else given the data structures.. + + hts_expand0(bcf_info_t,out->n_info+1,out->d.m_info,out->d.info); + out->d.info[out->n_info].key = id; + out->d.info[out->n_info].type = inf->type; + out->d.info[out->n_info].len = inf->len; + out->d.info[out->n_info].v1.i = inf->v1.i; + out->d.info[out->n_info].v1.f = inf->v1.f; + out->d.info[out->n_info].vptr_off = inf->vptr_off; + out->d.info[out->n_info].vptr_len = inf->vptr_len; + out->d.info[out->n_info].vptr_free = 1; + out->d.info[out->n_info].vptr = (uint8_t*) malloc(inf->vptr_len+inf->vptr_off); + memcpy(out->d.info[out->n_info].vptr,inf->vptr-inf->vptr_off, inf->vptr_len+inf->vptr_off); + out->d.info[out->n_info].vptr += inf->vptr_off; + if ( (args->output_type & FT_BCF) && id!=bcf_hdr_id2int(hdr, BCF_DT_ID, key) ) + bcf_info_set_id(out, &out->d.info[out->n_info], id, &args->tmps); + out->d.shared_dirty |= BCF1_DIRTY_INF; + out->n_info++; + kitr = kh_put(strdict, tmph, key, &ret); + kh_val(tmph,kitr) = -(out->n_info-1); // arbitrary negative value + } + } + } + for (i=0; inrules; i++) + args->rules[i].merger(args->out_hdr, out, &args->rules[i]); + for (i=0; inAGR_info; i++) + { + AGR_info_t *agr = &ma->AGR_info[i]; + bcf_update_info(out_hdr,out,agr->hdr_tag,agr->buf,agr->nvals,agr->type); + } +} + +void update_AN_AC(bcf_hdr_t *hdr, bcf1_t *line) +{ + int32_t an = 0, *tmp = (int32_t*) malloc(sizeof(int)*line->n_allele); + int ret = bcf_calc_ac(hdr, line, tmp, BCF_UN_FMT); + if ( ret>0 ) + { + int i; + for (i=0; in_allele; i++) an += tmp[i]; + bcf_update_info_int32(hdr, line, "AN", &an, 1); + bcf_update_info_int32(hdr, line, "AC", tmp+1, line->n_allele-1); + } + free(tmp); +} + +void merge_GT(args_t *args, bcf_fmt_t **fmt_map, bcf1_t *out) +{ + bcf_srs_t *files = args->files; + bcf_hdr_t *out_hdr = args->out_hdr; + maux_t *ma = args->maux; + int i, ismpl = 0, nsamples = bcf_hdr_nsamples(out_hdr); + + int nsize = 0, msize = sizeof(int32_t); + for (i=0; inreaders; i++) + { + if ( !fmt_map[i] ) continue; + if ( fmt_map[i]->n > nsize ) nsize = fmt_map[i]->n; + } + + if ( ma->ntmp_arr < nsamples*nsize*msize ) + { + ma->ntmp_arr = nsamples*nsize*msize; + ma->tmp_arr = realloc(ma->tmp_arr, ma->ntmp_arr); + } + memset(ma->smpl_ploidy,0,nsamples*sizeof(int)); + + int default_gt = args->missing_to_ref ? bcf_gt_unphased(0) : bcf_gt_missing; + for (i=0; inreaders; i++) + { + bcf_sr_t *reader = &files->readers[i]; + bcf_hdr_t *hdr = reader->header; + bcf_fmt_t *fmt_ori = fmt_map[i]; + int32_t *tmp = (int32_t *) ma->tmp_arr + ismpl*nsize; + int irec = ma->buf[i].cur; + + int j, k; + if ( !fmt_ori ) + { + // missing values: assume maximum ploidy + for (j=0; jsmpl_ploidy[ismpl+j]++; } + tmp += nsize; + } + ismpl += bcf_hdr_nsamples(hdr); + continue; + } + + #define BRANCH(type_t, vector_end) { \ + type_t *p_ori = (type_t*) fmt_ori->p; \ + if ( !ma->buf[i].rec[irec].als_differ ) \ + { \ + /* the allele numbering is unchanged */ \ + for (j=0; jn; k++) \ + { \ + if ( p_ori[k]==vector_end ) break; /* smaller ploidy */ \ + ma->smpl_ploidy[ismpl+j]++; \ + if ( bcf_gt_is_missing(p_ori[k]) ) tmp[k] = 0; /* missing allele */ \ + else tmp[k] = p_ori[k]; \ + } \ + for (; kn; \ + } \ + ismpl += bcf_hdr_nsamples(hdr); \ + continue; \ + } \ + /* allele numbering needs to be changed */ \ + for (j=0; jn; k++) \ + { \ + if ( p_ori[k]==vector_end ) break; /* smaller ploidy */ \ + ma->smpl_ploidy[ismpl+j]++; \ + if ( bcf_gt_is_missing(p_ori[k]) ) tmp[k] = 0; /* missing allele */ \ + else \ + { \ + int al = (p_ori[k]>>1) - 1; \ + al = al<=0 ? al + 1 : ma->buf[i].rec[irec].map[al] + 1; \ + tmp[k] = (al << 1) | ((p_ori[k])&1); \ + } \ + } \ + for (; kn; \ + } \ + ismpl += bcf_hdr_nsamples(hdr); \ + } + switch (fmt_ori->type) + { + case BCF_BT_INT8: BRANCH(int8_t, bcf_int8_vector_end); break; + case BCF_BT_INT16: BRANCH(int16_t, bcf_int16_vector_end); break; + case BCF_BT_INT32: BRANCH(int32_t, bcf_int32_vector_end); break; + default: error("Unexpected case: %d\n", fmt_ori->type); + } + #undef BRANCH + } + bcf_update_format_int32(out_hdr, out, "GT", (int32_t*)ma->tmp_arr, nsamples*nsize); +} + +void merge_format_field(args_t *args, bcf_fmt_t **fmt_map, bcf1_t *out) +{ + bcf_srs_t *files = args->files; + bcf_hdr_t *out_hdr = args->out_hdr; + maux_t *ma = args->maux; + int i, ismpl = 0, nsamples = bcf_hdr_nsamples(out_hdr); + + const char *key = NULL; + int nsize = 0, length = BCF_VL_FIXED, type = -1; + for (i=0; inreaders; i++) + { + if ( !maux_get_line(args,i) ) continue; + if ( !fmt_map[i] ) continue; + if ( !key ) key = files->readers[i].header->id[BCF_DT_ID][fmt_map[i]->id].key; + type = fmt_map[i]->type; + if ( IS_VL_G(files->readers[i].header, fmt_map[i]->id) ) + { + length = BCF_VL_G; + nsize = out->n_allele*(out->n_allele + 1)/2; + break; + } + if ( IS_VL_A(files->readers[i].header, fmt_map[i]->id) ) + { + length = BCF_VL_A; + nsize = out->n_allele - 1; + break; + } + if ( IS_VL_R(files->readers[i].header, fmt_map[i]->id) ) + { + length = BCF_VL_R; + nsize = out->n_allele; + break; + } + if ( fmt_map[i]->n > nsize ) nsize = fmt_map[i]->n; + } + + int msize = sizeof(float)>sizeof(int32_t) ? sizeof(float) : sizeof(int32_t); + if ( ma->ntmp_arr < nsamples*nsize*msize ) + { + ma->ntmp_arr = nsamples*nsize*msize; + ma->tmp_arr = realloc(ma->tmp_arr, ma->ntmp_arr); + } + + // Fill the temp array for all samples by collecting values from all files + for (i=0; inreaders; i++) + { + bcf_sr_t *reader = &files->readers[i]; + bcf_hdr_t *hdr = reader->header; + bcf_fmt_t *fmt_ori = fmt_map[i]; + bcf1_t *line = maux_get_line(args, i); + int irec = ma->buf[i].cur; + if ( fmt_ori ) + { + type = fmt_ori->type; + int nals_ori = line->n_allele; + if ( length==BCF_VL_G ) + { + // if all fields are missing then n==1 is valid + if ( fmt_ori->n!=1 && fmt_ori->n != nals_ori*(nals_ori+1)/2 && fmt_map[i]->n != nals_ori ) + error("Incorrect number of %s fields (%d) at %s:%d, cannot merge.\n", key,fmt_ori->n,bcf_seqname(args->out_hdr,out),out->pos+1); + } + else if ( length==BCF_VL_A ) + { + if ( fmt_ori->n!=1 && fmt_ori->n != nals_ori-1 ) + error("Incorrect number of %s fields (%d) at %s:%d, cannot merge.\n", key,fmt_ori->n,bcf_seqname(args->out_hdr,out),out->pos+1); + } + else if ( length==BCF_VL_R ) + { + if ( fmt_ori->n!=1 && fmt_ori->n != nals_ori ) + error("Incorrect number of %s fields (%d) at %s:%d, cannot merge.\n", key,fmt_ori->n,bcf_seqname(args->out_hdr,out),out->pos+1); + } + } + + // set the values + #define BRANCH(tgt_type_t, src_type_t, src_is_missing, src_is_vector_end, tgt_set_missing, tgt_set_vector_end) { \ + int j, l, k; \ + tgt_type_t *tgt = (tgt_type_t *) ma->tmp_arr + ismpl*nsize; \ + if ( !fmt_ori ) \ + { \ + /* the field is not present in this file, set missing values */ \ + for (j=0; jp; \ + if ( (length!=BCF_VL_G && length!=BCF_VL_A && length!=BCF_VL_R) || (line->n_allele==out->n_allele && !ma->buf[i].rec[irec].als_differ) ) \ + { \ + /* alleles unchanged, copy over */ \ + for (j=0; jn; l++) \ + { \ + if ( src_is_vector_end ) break; \ + else if ( src_is_missing ) tgt_set_missing; \ + else *tgt = *src; \ + tgt++; src++; \ + } \ + for (k=l; kn - l; \ + } \ + ismpl += bcf_hdr_nsamples(hdr); \ + continue; \ + } \ + /* allele numbering needs to be changed */ \ + if ( length==BCF_VL_G ) \ + { \ + /* Number=G tags */ \ + for (j=0; jtmp_arr + (ismpl+j)*nsize; \ + src = (src_type_t*) fmt_ori->p + j*fmt_ori->n; \ + if ( (src_is_missing && fmt_ori->n==1) || (++src && src_is_vector_end) ) \ + { \ + /* tag with missing value "." */ \ + tgt_set_missing; \ + for (l=1; lsmpl_ploidy[ismpl+j]==1 ? out->n_allele : out->n_allele*(out->n_allele + 1)/2; \ + for (l=0; lsmpl_ploidy[ismpl+j]==1 ) \ + { \ + /* Haploid */ \ + int iori, inew; \ + for (iori=0; iorin_allele; iori++) \ + { \ + inew = ma->buf[i].rec[irec].map[iori]; \ + src = (src_type_t*) fmt_ori->p + j*fmt_ori->n + iori; \ + tgt = (tgt_type_t *) ma->tmp_arr + (ismpl+j)*nsize + inew; \ + if ( src_is_vector_end ) break; \ + if ( src_is_missing ) tgt_set_missing; \ + else *tgt = *src; \ + } \ + } \ + else \ + { \ + /* Diploid */ \ + int iori,jori, inew,jnew; \ + for (iori=0; iorin_allele; iori++) \ + { \ + inew = ma->buf[i].rec[irec].map[iori]; \ + for (jori=0; jori<=iori; jori++) \ + { \ + jnew = ma->buf[i].rec[irec].map[jori]; \ + int kori = iori*(iori+1)/2 + jori; \ + int knew = inew>jnew ? inew*(inew+1)/2 + jnew : jnew*(jnew+1)/2 + inew; \ + src = (src_type_t*) fmt_ori->p + j*fmt_ori->n + kori; \ + tgt = (tgt_type_t *) ma->tmp_arr + (ismpl+j)*nsize + knew; \ + if ( src_is_vector_end ) \ + { \ + iori = line->n_allele; \ + break; \ + } \ + if ( src_is_missing ) tgt_set_missing; \ + else *tgt = *src; \ + } \ + } \ + } \ + } \ + } \ + else \ + { \ + /* Number=A or Number=R tags */ \ + int ifrom = length==BCF_VL_A ? 1 : 0; \ + for (j=0; jtmp_arr + (ismpl+j)*nsize; \ + src = (src_type_t*) (fmt_ori->p + j*fmt_ori->size); \ + if ( (src_is_missing && fmt_ori->n==1) || (++src && src_is_vector_end) ) \ + { \ + /* tag with missing value "." */ \ + tgt_set_missing; \ + for (l=1; lp + j*fmt_ori->size); \ + for (l=0; ln_allele; iori++) \ + { \ + inew = ma->buf[i].rec[irec].map[iori] - ifrom; \ + tgt = (tgt_type_t *) ma->tmp_arr + (ismpl+j)*nsize + inew; \ + if ( src_is_vector_end ) break; \ + if ( src_is_missing ) tgt_set_missing; \ + else *tgt = *src; \ + src++; \ + } \ + } \ + } \ + ismpl += bcf_hdr_nsamples(hdr); \ + } + switch (type) + { + case BCF_BT_INT8: BRANCH(int32_t, int8_t, *src==bcf_int8_missing, *src==bcf_int8_vector_end, *tgt=bcf_int32_missing, *tgt=bcf_int32_vector_end); break; + case BCF_BT_INT16: BRANCH(int32_t, int16_t, *src==bcf_int16_missing, *src==bcf_int16_vector_end, *tgt=bcf_int32_missing, *tgt=bcf_int32_vector_end); break; + case BCF_BT_INT32: BRANCH(int32_t, int32_t, *src==bcf_int32_missing, *src==bcf_int32_vector_end, *tgt=bcf_int32_missing, *tgt=bcf_int32_vector_end); break; + case BCF_BT_FLOAT: BRANCH(float, float, bcf_float_is_missing(*src), bcf_float_is_vector_end(*src), bcf_float_set_missing(*tgt), bcf_float_set_vector_end(*tgt)); break; + case BCF_BT_CHAR: BRANCH(uint8_t, uint8_t, *src==bcf_str_missing, *src==bcf_str_vector_end, *tgt=bcf_str_missing, *tgt=bcf_str_vector_end); break; + default: error("Unexpected case: %d, %s\n", type, key); + } + #undef BRANCH + } + if ( type==BCF_BT_FLOAT ) + bcf_update_format_float(out_hdr, out, key, (float*)ma->tmp_arr, nsamples*nsize); + else if ( type==BCF_BT_CHAR ) + bcf_update_format_char(out_hdr, out, key, (float*)ma->tmp_arr, nsamples*nsize); + else + bcf_update_format_int32(out_hdr, out, key, (int32_t*)ma->tmp_arr, nsamples*nsize); +} + +void merge_format(args_t *args, bcf1_t *out) +{ + bcf_srs_t *files = args->files; + bcf_hdr_t *out_hdr = args->out_hdr; + maux_t *ma = args->maux; + if ( !ma->nfmt_map ) + { + ma->nfmt_map = 2; + ma->fmt_map = (bcf_fmt_t**) calloc(ma->nfmt_map*files->nreaders, sizeof(bcf_fmt_t*)); + } + else + memset(ma->fmt_map, 0, ma->nfmt_map*files->nreaders*sizeof(bcf_fmt_t**)); + + khiter_t kitr; + strdict_t *tmph = args->tmph; + kh_clear(strdict, tmph); + int i, j, ret, has_GT = 0, max_ifmt = 0; // max fmt index + for (i=0; inreaders; i++) + { + bcf1_t *line = maux_get_line(args,i); + if ( !line ) continue; + bcf_sr_t *reader = &files->readers[i]; + bcf_hdr_t *hdr = reader->header; + for (j=0; jn_fmt; j++) + { + // Wat this tag already seen? + bcf_fmt_t *fmt = &line->d.fmt[j]; + const char *key = hdr->id[BCF_DT_ID][fmt->id].key; + kitr = kh_get(strdict, tmph, key); + + int ifmt; + if ( kitr != kh_end(tmph) ) + ifmt = kh_value(tmph, kitr); // seen + else + { + // new FORMAT tag + if ( key[0]=='G' && key[1]=='T' && key[2]==0 ) { has_GT = 1; ifmt = 0; } + else + { + ifmt = ++max_ifmt; + if ( max_ifmt >= ma->nfmt_map ) + { + ma->fmt_map = (bcf_fmt_t**) realloc(ma->fmt_map, sizeof(bcf_fmt_t*)*(max_ifmt+1)*files->nreaders); + memset(ma->fmt_map+ma->nfmt_map*files->nreaders, 0, (max_ifmt-ma->nfmt_map+1)*files->nreaders*sizeof(bcf_fmt_t*)); + ma->nfmt_map = max_ifmt+1; + } + } + kitr = kh_put(strdict, tmph, key, &ret); + kh_value(tmph, kitr) = ifmt; + } + ma->fmt_map[ifmt*files->nreaders+i] = fmt; + } + // Check if the allele numbering must be changed + int irec = ma->buf[i].cur; + for (j=1; jn_allele; j++) + if ( ma->buf[i].rec[irec].map[j]!=j ) break; + ma->buf[i].rec[irec].als_differ = j==line->n_allele ? 0 : 1; + } + + out->n_sample = bcf_hdr_nsamples(out_hdr); + if ( has_GT ) + merge_GT(args, ma->fmt_map, out); + update_AN_AC(out_hdr, out); + + for (i=1; i<=max_ifmt; i++) + merge_format_field(args, &ma->fmt_map[i*files->nreaders], out); + out->d.indiv_dirty = 1; +} + +void gvcf_set_alleles(args_t *args) +{ + int i,k; + bcf_srs_t *files = args->files; + maux_t *maux = args->maux; + gvcf_aux_t *gaux = maux->gvcf; + maux->nals = 0; + + for (i=0; inreaders; i++) + { + if ( !gaux[i].active ) continue; + bcf1_t *line = maux_get_line(args, i); + int irec = maux->buf[i].cur; + + hts_expand(int, line->n_allele, maux->buf[i].rec[irec].mmap, maux->buf[i].rec[irec].map); + if ( !maux->nals ) // first record, copy the alleles to the output + { + maux->nals = line->n_allele; + hts_expand0(char*, maux->nals, maux->mals, maux->als); + hts_expand0(int, maux->nals, maux->ncnt, maux->cnt); + for (k=0; knals; k++) + { + if ( maux->als[k] ) free(maux->als[k]); + maux->als[k] = strdup(line->d.allele[k]); + maux->buf[i].rec[irec].map[k] = k; + } + } + else + { + maux->als = merge_alleles(line->d.allele, line->n_allele, maux->buf[i].rec[irec].map, maux->als, &maux->nals, &maux->mals); + if ( !maux->als ) + { + bcf_hdr_t *hdr = bcf_sr_get_header(args->files,i); + error("Failed to merge alleles at %s:%d\n",bcf_seqname(hdr,line),line->pos+1); + } + } + } +} + +/* + Output staged gVCF blocks, end is the last position of the block. Assuming + gaux[i].active flags are set and maux_get_line returns correct lines. +*/ +void gvcf_write_block(args_t *args, int start, int end) +{ + int i; + maux_t *maux = args->maux; + gvcf_aux_t *gaux = maux->gvcf; + assert(gaux); + + // Update POS + int min = INT_MAX; + char ref = 'N'; + for (i=0; ifiles->nreaders; i++) + { + if ( !gaux[i].active ) continue; + if ( ref=='N' && gaux[i].line->pos==start ) ref = gaux[i].line->d.allele[0][0]; + gaux[i].line->pos = start; + } + for (i=0; ifiles->nreaders; i++) + { + if ( !gaux[i].active ) continue; + if ( gaux[i].end < start ) + { + gaux[i].active = 0; + maux->buf[i].cur = -1; + continue; + } + gaux[i].line->d.allele[0][0] = ref; + if ( min > gaux[i].end ) min = gaux[i].end; + } + // Check for valid gVCF blocks in this region + if ( min==INT_MAX ) + { + assert(0); + maux->gvcf_min = 0; + return; + } + + bcf1_t *out = args->out_line; + + gvcf_set_alleles(args); + + // Merge the staged lines + merge_chrom2qual(args, out); + merge_filter(args, out); + merge_info(args, out); + merge_format(args, out); + + if ( args->gvcf_fai && out->d.allele[0][0]=='N' ) + { + int slen = 0; + char *seq = faidx_fetch_seq(args->gvcf_fai,maux->chr,out->pos,out->pos,&slen); + if (slen) + { + out->d.allele[0][0] = seq[0]; + free(seq); + } + } + + // Update END boundary + if ( end > start ) + { + end++; + bcf_update_info_int32(args->out_hdr, out, "END", &end, 1); + } + else + bcf_update_info_int32(args->out_hdr, out, "END", NULL, 0); + bcf_write1(args->out_fh, args->out_hdr, out); + bcf_clear1(out); + + + // Inactivate blocks which do not extend beyond END and find new gvcf_min + min = INT_MAX; + for (i=0; ifiles->nreaders; i++) + { + if ( !gaux[i].active ) continue; + if ( gaux[i].end < end ) + { + gaux[i].active = 0; + maux->buf[i].cur = -1; + continue; + } + // next min END position bigger than the current one + if ( maux->gvcf_min < gaux[i].end+1 && min > gaux[i].end+1 ) min = gaux[i].end + 1; + } + maux->gvcf_min = min==INT_MAX ? 0 : min; +} + +/* + Flush staged gVCF blocks. Flush everything if there are no more lines + (done=1) or if there is a new chromosome. If still on the same chromosome, + all hanging blocks must be ended by creating new records: + A + 1 END=10 + B + 3 END=7 + C + 3 END=5 + out + 1 END=2 A . . + 3 END=5 A B C + 6 END=7 A B . + 8 END=10 A . . + +*/ +void gvcf_flush(args_t *args, int done) +{ + int i; + maux_t *maux = args->maux; + + if ( !maux->chr ) return; // first time here, nothing to flush + + int flush_until = INT_MAX; + if ( !done ) + { + // Get current position and chromosome + for (i=0; in; i++) + if ( bcf_sr_has_line(maux->files,i) ) break; + bcf1_t *line = bcf_sr_get_line(maux->files,i); + bcf_hdr_t *hdr = bcf_sr_get_header(maux->files,i); + + if ( !strcmp(maux->chr,bcf_seqname(hdr,line)) ) flush_until = line->pos; // still on the same chr + } + + // When called on a region, trim the blocks accordingly + int start = maux->gvcf_break>=0 ? maux->gvcf_break + 1 : maux->pos; + if ( args->regs ) + { + int rstart = -1, rend = -1; + if ( regidx_overlap(args->regs,maux->chr,start,flush_until,args->regs_itr) ) + { + // In case there are multiple regions, we treat them as one + rstart = args->regs_itr->beg; + while ( regitr_overlap(args->regs_itr) ) rend = args->regs_itr->end; + } + if ( rstart > start ) start = rstart; + if ( rend < flush_until ) flush_until = rend+1; + } + + // output all finished blocks + while ( maux->gvcf_min && start < flush_until ) + { + // does the block end before the new line or is it interrupted? + int tmp = maux->gvcf_min < flush_until ? maux->gvcf_min : flush_until; + if ( start > tmp-1 ) break; + gvcf_write_block(args,start,tmp-1); // gvcf_min is 1-based + start = tmp; + } +} + +/* + Check incoming lines for new gVCF blocks, set pointer to the current source + buffer (gvcf or readers). In contrast to gvcf_flush, this function can be + called only after maux_reset as it relies on updated maux buffers. +*/ +void gvcf_stage(args_t *args, int pos) +{ + maux_t *maux = args->maux; + gvcf_aux_t *gaux = maux->gvcf; + bcf_srs_t *files = args->files; + int32_t *end = (int32_t*) maux->tmp_arr; + int i, nend = maux->ntmp_arr / sizeof(int32_t); + + maux->gvcf_break = -1; + maux->gvcf_min = INT_MAX; + for (i=0; inreaders; i++) + { + if ( gaux[i].active ) + { + // gvcf block should not overlap with another record + if ( maux->gvcf_min > gaux[i].end+1 ) maux->gvcf_min = gaux[i].end + 1; + maux->buf[i].beg = 0; + maux->buf[i].end = 1; + maux->buf[i].cur = 0; + continue; + } + + // Does any of the lines have END set? It is enough to check only the + // first line, there should be no duplicate records with END in gVCF + + if ( maux->buf[i].beg==maux->buf[i].end ) continue; // no new record + + int irec = maux->buf[i].beg; + bcf_hdr_t *hdr = bcf_sr_get_header(files, i); + bcf1_t *line = args->files->readers[i].buffer[irec]; + int ret = bcf_get_info_int32(hdr,line,"END",&end,&nend); + if ( ret==1 ) + { + // END is set, this is a new gVCF block. Cache this line in gaux[i] and swap with + // an empty record: the gaux line must be kept until we reach its END. + gaux[i].active = 1; + gaux[i].end = end[0] - 1; + SWAP(bcf1_t*,args->files->readers[i].buffer[irec],gaux[i].line); + gaux[i].line->pos = pos; + + maux->buf[i].lines = &gaux[i].line; + maux->buf[i].beg = 0; + maux->buf[i].end = 1; + maux->buf[i].cur = 0; + + // Set the rid,pos of the swapped line in the buffer or else the + // synced reader will have a problem with the next line + // + args->files->readers[i].buffer[irec]->rid = maux->buf[i].rid; + args->files->readers[i].buffer[irec]->pos = maux->pos; + + // Update block offsets + if ( maux->gvcf_min > gaux[i].end+1 ) maux->gvcf_min = gaux[i].end + 1; + } + else + maux->gvcf_break = line->pos; // must break the gvcf block + } + maux->ntmp_arr = nend * sizeof(int32_t); + maux->tmp_arr = end; + if ( maux->gvcf_min==INT_MAX ) maux->gvcf_min = 0; +} + + +void debug_buffers(FILE *fp, bcf_srs_t *files); +void debug_buffer(FILE *fp, bcf_srs_t *files, int reader); + +/* + Flush all buffered and processed records with the same coordinate. + Note that synced reader discards buffer[0], so that needs to stay + untouched. +*/ +void clean_buffer(args_t *args) +{ + maux_t *ma = args->maux; + + int ir; + for (ir=0; irn; ir++) + { + // Invalidate pointer to reader's buffer or else gvcf_flush will attempt + // to use the old lines via maux_get_line() + if ( ma->gvcf && !ma->gvcf[ir].active ) ma->buf[ir].cur = -1; + + bcf_sr_t *reader = bcf_sr_get_reader(args->files,ir); + if ( !reader->nbuffer ) continue; // nothing to clean + + bcf1_t **buf = reader->buffer; + if ( buf[1]->rid!=ma->buf[ir].rid || buf[1]->pos!=ma->pos ) continue; // nothing to flush + + int a = 1, b = 2; + while ( b<=reader->nbuffer && buf[b]->rid==ma->buf[ir].rid && buf[b]->pos==ma->pos ) b++; + // b now points to the first line we want to preserve + while ( b<=reader->nbuffer ) + { + SWAP(bcf1_t*, buf[a], buf[b]); + a++; b++; + } + reader->nbuffer -= b-a; + } +} + +void debug_maux(args_t *args) +{ + bcf_srs_t *files = args->files; + maux_t *maux = args->maux; + int j,k,l; + + fprintf(stderr,"Alleles to merge at %d, nals=%d\n", maux->pos+1,maux->nals); + for (j=0; jnreaders; j++) + { + bcf_sr_t *reader = &files->readers[j]; + buffer_t *buf = &maux->buf[j]; + fprintf(stderr," reader %d: ", j); + for (k=buf->beg; kend; k++) + { + if ( buf->rec[k].skip & SKIP_DONE ) continue; + bcf1_t *line = reader->buffer[k]; + fprintf(stderr,"\t"); + if ( buf->rec[k].skip ) fprintf(stderr,"["); // this record will not be merged in this round + for (l=0; ln_allele; l++) + fprintf(stderr,"%s%s", l==0?"":",", line->d.allele[l]); + if ( buf->rec[k].skip ) fprintf(stderr,"]"); + } + fprintf(stderr,"\n"); + } + fprintf(stderr," counts: "); + for (j=0; jnals; j++) fprintf(stderr,"%s %dx %s", j==0?"":",",maux->cnt[j], maux->als[j]); + fprintf(stderr,"\n\n"); +} + + +/* + Determine which line should be merged from which reader: go through all + readers and all buffered lines, expand REF,ALT and try to match lines with + the same ALTs. + */ +int can_merge(args_t *args) +{ + bcf_srs_t *files = args->files; + int snp_mask = (VCF_SNP<<1)|(VCF_MNP<<1), indel_mask = VCF_INDEL<<1, ref_mask = 1; + maux_t *maux = args->maux; + gvcf_aux_t *gaux = maux->gvcf; + char *id = NULL, ref = 'N'; + maux->var_types = maux->nals = 0; + + int i,j,k, ntodo = 0; + for (i=0; inreaders; i++) + { + buffer_t *buf = &maux->buf[i]; + + if ( gaux && gaux[i].active ) + { + // skip readers with active gvcf blocks + buf->rec[buf->beg].skip = SKIP_DIFF; + continue; + } + for (j=buf->beg; jend; j++) + { + if ( buf->rec[j].skip & SKIP_DONE ) continue; + + buf->rec[j].skip = SKIP_DIFF; + ntodo++; + + if ( args->merge_by_id ) + id = buf->lines[j]->d.id; + else + { + int var_type = bcf_get_variant_types(buf->lines[j]); + maux->var_types |= var_type ? var_type<<1 : 1; + } + } + + // for gvcf: find out REF at this position + if ( buf->beg < buf->end && ref=='N' ) + ref = buf->lines[buf->beg]->d.allele[0][0]; + } + if ( !ntodo ) return 0; + + // In this loop we select from each reader compatible candidate lines. + // (i.e. SNPs or indels). Go through all files and all lines at this + // position and normalize relevant alleles. + // REF-only sites may be associated with both SNPs and indels. + for (i=0; inreaders; i++) + { + bcf_sr_t *reader = &files->readers[i]; + buffer_t *buf = &maux->buf[i]; + + if ( gaux && gaux[i].active ) + { + gaux[i].line->d.allele[0][0] = ref; + gaux[i].line->pos = maux->pos; + } + + for (j=buf->beg; jend; j++) + { + if ( buf->rec[j].skip & SKIP_DONE ) continue; + + bcf1_t *line = buf->lines[j]; // ptr to reader's buffer or gvcf buffer + + int line_type = bcf_get_variant_types(line); + line_type = line_type ? line_type<<1 : 1; + + // select relevant lines + if ( args->merge_by_id ) + { + if ( strcmp(id,line->d.id) ) continue; + } + else + { + if ( args->collapse==COLLAPSE_NONE && maux->nals ) + { + // All alleles of the tested record must be present in the + // selected maux record plus variant types must be the same + if ( (maux->var_types & line_type) != line_type ) continue; + if ( vcmp_set_ref(args->vcmp,maux->als[0],line->d.allele[0]) < 0 ) continue; // refs not compatible + for (k=1; kn_allele; k++) + { + if ( vcmp_find_allele(args->vcmp,maux->als+1,maux->nals-1,line->d.allele[k])>=0 ) break; + } + if ( !(line_type&ref_mask) && k==line->n_allele ) continue; // not a REF-only site and there is no matching allele + } + if ( !(args->collapse&COLLAPSE_ANY) ) + { + // Merge: + // - SNPs+SNPs+MNPs+REF if -m both,snps + // - indels+indels+REF if -m both,indels, REF only if SNPs are not present + // - SNPs come first + if ( line_type & indel_mask ) + { + if ( !(line_type&snp_mask) && maux->var_types&snp_mask ) continue; // SNPs come first + if ( args->do_gvcf && maux->var_types&ref_mask ) continue; // never merge indels with gVCF blocks + } + } + } + buf->rec[j].skip = 0; + + hts_expand(int, line->n_allele, buf->rec[j].mmap, buf->rec[j].map); + if ( !maux->nals ) // first record, copy the alleles to the output + { + maux->nals = line->n_allele; + hts_expand0(char*, maux->nals, maux->mals, maux->als); + hts_expand0(int, maux->nals, maux->ncnt, maux->cnt); + for (k=0; knals; k++) + { + free(maux->als[k]); + maux->als[k] = strdup(line->d.allele[k]); + buf->rec[j].map[k] = k; + maux->cnt[k] = 1; + } + continue; + } + // normalize alleles + maux->als = merge_alleles(line->d.allele, line->n_allele, buf->rec[j].map, maux->als, &maux->nals, &maux->mals); + if ( !maux->als ) error("Failed to merge alleles at %s:%d in %s\n",bcf_seqname(args->out_hdr,line),line->pos+1,reader->fname); + hts_expand0(int, maux->nals, maux->ncnt, maux->cnt); + for (k=1; kn_allele; k++) + maux->cnt[ buf->rec[j].map[k] ]++; // how many times an allele appears in the files + maux->cnt[0]++; + } + } + return 1; +} + +/* + Select records that have the same alleles; the input ordering of indels + must not matter. Multiple VCF lines can be emitted from this loop. + We expect only very few alleles and not many records with the same + position in the buffers, therefore the nested loops should not slow us + much. +*/ +void stage_line(args_t *args) +{ + int snp_mask = (VCF_SNP<<1)|(VCF_MNP<<1), indel_mask = VCF_INDEL<<1, ref_mask = 1; + bcf_srs_t *files = args->files; + maux_t *maux = args->maux; + + // debug_maux(args); + + // take the most frequent allele present in multiple files, REF is skipped + int i,j,k,icnt = 1; + for (i=2; inals; i++) + if ( maux->cnt[i] > maux->cnt[icnt] ) icnt = i; + + int nout = 0; + for (i=0; inreaders; i++) + { + buffer_t *buf = &maux->buf[i]; + buf->cur = -1; + if ( buf->beg >= buf->end ) continue; // no lines in the buffer + + // find lines with the same allele + for (j=buf->beg; jend; j++) + { + if ( buf->rec[j].skip ) continue; // done or not compatible + if ( args->merge_by_id ) break; + if ( maux->nals==1 && buf->lines[j]->n_allele==1 ) break; // REF-only record + + for (k=0; klines[j]->n_allele; k++) + if ( icnt==buf->rec[j].map[k] ) break; + + if ( klines[j]->n_allele ) break; + } + if ( j>=buf->end ) + { + // no matching allele found in this file + if ( args->collapse==COLLAPSE_NONE ) continue; + + for (j=buf->beg; jend; j++) + { + if ( buf->rec[j].skip ) continue; // done or not compatible + if ( args->collapse&COLLAPSE_ANY ) break; // anything can be merged + int line_type = bcf_get_variant_types(buf->lines[j]); + if ( maux->var_types&snp_mask && line_type&VCF_SNP && (args->collapse&COLLAPSE_SNPS) ) break; + if ( maux->var_types&indel_mask && line_type&VCF_INDEL && (args->collapse&COLLAPSE_INDELS) ) break; + if ( line_type==VCF_REF ) + { + if ( maux->var_types&snp_mask && (args->collapse&COLLAPSE_SNPS) ) break; + if ( maux->var_types&indel_mask && (args->collapse&COLLAPSE_INDELS) ) break; + if ( maux->var_types&ref_mask ) break; + } + else if ( maux->var_types&ref_mask ) + { + if ( line_type&snp_mask && (args->collapse&COLLAPSE_SNPS) ) break; + if ( line_type&indel_mask && (args->collapse&COLLAPSE_INDELS) ) break; + } + } + } + if ( jend ) + { + // found a suitable line for merging + buf->cur = j; + + // mark as finished so that it's ignored next time + buf->rec[j].skip = SKIP_DONE; + nout++; + } + } + assert( nout ); +} + +void merge_line(args_t *args) +{ + if ( args->regs ) + { + if ( !regidx_overlap(args->regs,args->maux->chr,args->maux->pos,args->maux->pos,NULL) ) return; + } + + bcf1_t *out = args->out_line; + merge_chrom2qual(args, out); + merge_filter(args, out); + merge_info(args, out); + if ( args->do_gvcf ) + bcf_update_info_int32(args->out_hdr, out, "END", NULL, 0); + merge_format(args, out); + bcf_write1(args->out_fh, args->out_hdr, out); + bcf_clear1(out); +} + +void bcf_hdr_append_version(bcf_hdr_t *hdr, int argc, char **argv, const char *cmd) +{ + kstring_t str = {0,0,0}; + ksprintf(&str,"##%sVersion=%s+htslib-%s\n", cmd, bcftools_version(), hts_version()); + bcf_hdr_append(hdr,str.s); + + str.l = 0; + ksprintf(&str,"##%sCommand=%s", cmd, argv[0]); + int i; + for (i=1; ioutput_fname, strerror(errno)); + if ( args->n_threads ) hts_set_opt(args->out_fh, HTS_OPT_THREAD_POOL, args->files->p); //hts_set_threads(args->out_fh, args->n_threads); + args->out_hdr = bcf_hdr_init("w"); + + if ( args->header_fname ) + { + if ( bcf_hdr_set(args->out_hdr,args->header_fname) ) error("Could not read/parse the header: %s\n", args->header_fname); + } + else + { + int i; + for (i=0; ifiles->nreaders; i++) + { + char buf[10]; snprintf(buf,10,"%d",i+1); + merge_headers(args->out_hdr, args->files->readers[i].header,buf,args->force_samples); + } + if (args->record_cmd_line) bcf_hdr_append_version(args->out_hdr, args->argc, args->argv, "bcftools_merge"); + bcf_hdr_sync(args->out_hdr); + } + info_rules_init(args); + + bcf_hdr_set_version(args->out_hdr, bcf_hdr_get_version(args->files->readers[0].header)); + bcf_hdr_write(args->out_fh, args->out_hdr); + if ( args->header_only ) + { + bcf_hdr_destroy(args->out_hdr); + hts_close(args->out_fh); + return; + } + + if ( args->collapse==COLLAPSE_NONE ) args->vcmp = vcmp_init(); + args->maux = maux_init(args); + args->out_line = bcf_init1(); + args->tmph = kh_init(strdict); + + while ( bcf_sr_next_line(args->files) ) + { + // output cached gVCF blocks which end before the new record + if ( args->do_gvcf ) + gvcf_flush(args,0); + + maux_reset(args->maux); + + // determine which of the new records are gvcf blocks + if ( args->do_gvcf ) + gvcf_stage(args, args->maux->pos); + + while ( can_merge(args) ) + { + stage_line(args); + merge_line(args); + } + clean_buffer(args); + } + if ( args->do_gvcf ) + gvcf_flush(args,1); + + info_rules_destroy(args); + maux_destroy(args->maux); + bcf_hdr_destroy(args->out_hdr); + hts_close(args->out_fh); + bcf_destroy1(args->out_line); + kh_destroy(strdict, args->tmph); + if ( args->tmps.m ) free(args->tmps.s); + if ( args->vcmp ) vcmp_destroy(args->vcmp); +} + +static void usage(void) +{ + fprintf(stderr, "\n"); + fprintf(stderr, "About: Merge multiple VCF/BCF files from non-overlapping sample sets to create one multi-sample file.\n"); + fprintf(stderr, " Note that only records from different files can be merged, never from the same file. For\n"); + fprintf(stderr, " \"vertical\" merge take a look at \"bcftools norm\" instead.\n"); + fprintf(stderr, "Usage: bcftools merge [options] [...]\n"); + fprintf(stderr, "\n"); + fprintf(stderr, "Options:\n"); + fprintf(stderr, " --force-samples resolve duplicate sample names\n"); + fprintf(stderr, " --print-header print only the merged header and exit\n"); + fprintf(stderr, " --use-header use the provided header\n"); + fprintf(stderr, " -0 --missing-to-ref assume genotypes at missing sites are 0/0\n"); + fprintf(stderr, " -f, --apply-filters require at least one of the listed FILTER strings (e.g. \"PASS,.\")\n"); + fprintf(stderr, " -F, --filter-logic remove filters if some input is PASS (\"x\"), or apply all filters (\"+\") [+]\n"); + fprintf(stderr, " -g, --gvcf <-|ref.fa> merge gVCF blocks, INFO/END tag is expected. Implies -i QS:sum,MinDP:min,I16:sum,IDV:max,IMF:max\n"); + fprintf(stderr, " -i, --info-rules rules for merging INFO fields (method is one of sum,avg,min,max,join) or \"-\" to turn off the default [DP:sum,DP4:sum]\n"); + fprintf(stderr, " -l, --file-list read file names from the file\n"); + fprintf(stderr, " -m, --merge allow multiallelic records for , see man page for details [both]\n"); + fprintf(stderr, " --no-version do not append version and command line to the header\n"); + fprintf(stderr, " -o, --output write output to a file [standard output]\n"); + fprintf(stderr, " -O, --output-type 'b' compressed BCF; 'u' uncompressed BCF; 'z' compressed VCF; 'v' uncompressed VCF [v]\n"); + fprintf(stderr, " -r, --regions restrict to comma-separated list of regions\n"); + fprintf(stderr, " -R, --regions-file restrict to regions listed in a file\n"); + fprintf(stderr, " --threads number of extra output compression threads [0]\n"); + fprintf(stderr, "\n"); + exit(1); +} + +int main_vcfmerge(int argc, char *argv[]) +{ + int c; + args_t *args = (args_t*) calloc(1,sizeof(args_t)); + args->files = bcf_sr_init(); + args->argc = argc; args->argv = argv; + args->output_fname = "-"; + args->output_type = FT_VCF; + args->n_threads = 0; + args->record_cmd_line = 1; + args->collapse = COLLAPSE_BOTH; + int regions_is_file = 0; + + static struct option loptions[] = + { + {"help",no_argument,NULL,'h'}, + {"merge",required_argument,NULL,'m'}, + {"gvcf",required_argument,NULL,'g'}, + {"file-list",required_argument,NULL,'l'}, + {"missing-to-ref",no_argument,NULL,'0'}, + {"apply-filters",required_argument,NULL,'f'}, + {"use-header",required_argument,NULL,1}, + {"print-header",no_argument,NULL,2}, + {"force-samples",no_argument,NULL,3}, + {"output",required_argument,NULL,'o'}, + {"output-type",required_argument,NULL,'O'}, + {"threads",required_argument,NULL,9}, + {"regions",required_argument,NULL,'r'}, + {"regions-file",required_argument,NULL,'R'}, + {"info-rules",required_argument,NULL,'i'}, + {"no-version",no_argument,NULL,8}, + {"filter-logic",required_argument,NULL,'F'}, + {NULL,0,NULL,0} + }; + while ((c = getopt_long(argc, argv, "hm:f:r:R:o:O:i:l:g:F:0",loptions,NULL)) >= 0) { + switch (c) { + case 'F': + if ( !strcmp(optarg,"+") ) args->filter_logic = FLT_LOGIC_ADD; + else if ( !strcmp(optarg,"x") ) args->filter_logic = FLT_LOGIC_REMOVE; + else error("Filter logic not recognised: %s\n", optarg); + break; + case '0': args->missing_to_ref = 1; break; + case 'g': + args->do_gvcf = 1; + if ( strcmp("-",optarg) ) + { + args->gvcf_fai = fai_load(optarg); + if ( !args->gvcf_fai ) error("Failed to load the fai index: %s\n", optarg); + } + break; + case 'l': args->file_list = optarg; break; + case 'i': args->info_rules = optarg; break; + case 'o': args->output_fname = optarg; break; + case 'O': + switch (optarg[0]) { + case 'b': args->output_type = FT_BCF_GZ; break; + case 'u': args->output_type = FT_BCF; break; + case 'z': args->output_type = FT_VCF_GZ; break; + case 'v': args->output_type = FT_VCF; break; + default: error("The output type \"%s\" not recognised\n", optarg); + } + break; + case 'm': + args->collapse = COLLAPSE_NONE; + if ( !strcmp(optarg,"snps") ) args->collapse |= COLLAPSE_SNPS; + else if ( !strcmp(optarg,"indels") ) args->collapse |= COLLAPSE_INDELS; + else if ( !strcmp(optarg,"both") ) args->collapse |= COLLAPSE_BOTH; + else if ( !strcmp(optarg,"any") ) args->collapse |= COLLAPSE_ANY; + else if ( !strcmp(optarg,"all") ) args->collapse |= COLLAPSE_ANY; + else if ( !strcmp(optarg,"none") ) args->collapse = COLLAPSE_NONE; + else if ( !strcmp(optarg,"id") ) { args->collapse = COLLAPSE_NONE; args->merge_by_id = 1; } + else error("The -m type \"%s\" is not recognised.\n", optarg); + break; + case 'f': args->files->apply_filters = optarg; break; + case 'r': args->regions_list = optarg; break; + case 'R': args->regions_list = optarg; regions_is_file = 1; break; + case 1 : args->header_fname = optarg; break; + case 2 : args->header_only = 1; break; + case 3 : args->force_samples = 1; break; + case 9 : args->n_threads = strtol(optarg, 0, 0); break; + case 8 : args->record_cmd_line = 0; break; + case 'h': + case '?': usage(); + default: error("Unknown argument: %s\n", optarg); + } + } + if ( argc==optind && !args->file_list ) usage(); + if ( argc-optind<2 && !args->file_list ) usage(); + + args->files->require_index = 1; + if ( args->regions_list ) + { + if ( bcf_sr_set_regions(args->files, args->regions_list, regions_is_file)<0 ) + error("Failed to read the regions: %s\n", args->regions_list); + if ( regions_is_file ) + args->regs = regidx_init(args->regions_list,NULL,NULL,sizeof(char*),NULL); + else + { + args->regs = regidx_init(NULL,regidx_parse_reg,NULL,sizeof(char*),NULL); + if ( regidx_insert_list(args->regs,args->regions_list,',') !=0 ) error("Could not parse the regions: %s\n", args->regions_list); + regidx_insert(args->regs,NULL); + } + if ( !args->regs ) error("Could not parse the regions: %s\n", args->regions_list); + args->regs_itr = regitr_init(args->regs); + } + + if ( bcf_sr_set_threads(args->files, args->n_threads)<0 ) error("Failed to create threads\n"); + while (optindfiles, argv[optind]) ) error("Failed to open %s: %s\n", argv[optind],bcf_sr_strerror(args->files->errnum)); + optind++; + } + if ( args->file_list ) + { + int nfiles, i; + char **files = hts_readlines(args->file_list, &nfiles); + if ( !files ) error("Failed to read from %s\n", args->file_list); + for (i=0;ifiles, files[i]) ) error("Failed to open %s: %s\n", files[i],bcf_sr_strerror(args->files->errnum)); + for (i=0; ifiles); + if ( args->regs ) regidx_destroy(args->regs); + if ( args->regs_itr ) regitr_destroy(args->regs_itr); + if ( args->gvcf_fai ) fai_destroy(args->gvcf_fai); + free(args); + return 0; +} + diff --git a/vcfnorm.c b/vcfnorm.c new file mode 100644 index 0000000..3a1706b --- /dev/null +++ b/vcfnorm.c @@ -0,0 +1,1858 @@ +/* vcfnorm.c -- Left-align and normalize indels. + + Copyright (C) 2013-2016 Genome Research Ltd. + + Author: Petr Danecek + +Permission is hereby granted, free of charge, to any person obtaining a copy +of this software and associated documentation files (the "Software"), to deal +in the Software without restriction, including without limitation the rights +to use, copy, modify, merge, publish, distribute, sublicense, and/or sell +copies of the Software, and to permit persons to whom the Software is +furnished to do so, subject to the following conditions: + +The above copyright notice and this permission notice shall be included in +all copies or substantial portions of the Software. + +THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE +AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER +LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, +OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN +THE SOFTWARE. */ + +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include "bcftools.h" +#include "rbuf.h" + +#define CHECK_REF_EXIT 0 +#define CHECK_REF_WARN 1 +#define CHECK_REF_SKIP 2 +#define CHECK_REF_FIX 4 + +#define MROWS_SPLIT 1 +#define MROWS_MERGE 2 + +// for -m+, mapping from allele indexes of a single input record +// to allele indexes of output record +typedef struct +{ + int nals, mals, *map; +} +map_t; + +typedef struct +{ + char *tseq, *seq; + int mseq; + bcf1_t **lines, **tmp_lines, **alines, **blines, *mrow_out; + int ntmp_lines, mtmp_lines, nalines, malines, nblines, mblines; + map_t *maps; // mrow map for each buffered record + char **als; + int mmaps, nals, mals; + uint8_t *tmp_arr1, *tmp_arr2, *diploid; + int ntmp_arr1, ntmp_arr2; + kstring_t *tmp_str; + kstring_t *tmp_als, tmp_als_str; + int ntmp_als; + rbuf_t rbuf; + int buf_win; // maximum distance between two records to consider + int aln_win; // the realignment window size (maximum repeat size) + bcf_srs_t *files; // using the synced reader only for -r option + bcf_hdr_t *hdr; + faidx_t *fai; + struct { int tot, set, swap; } nref; + char **argv, *output_fname, *ref_fname, *vcf_fname, *region, *targets; + int argc, rmdup, output_type, n_threads, check_ref, strict_filter, do_indels; + int nchanged, nskipped, nsplit, ntotal, mrows_op, mrows_collapse, parsimonious; + int record_cmd_line; +} +args_t; + +static inline int replace_iupac_codes(char *seq, int nseq) +{ + // Replace ambiguity codes with N for now, it awaits to be seen what the VCF spec codifies in the end + int i, n = 0; + for (i=0; id.allele[0]); + int i, maxlen = reflen, len; + for (i=1; in_allele; i++) + { + int len = strlen(line->d.allele[i]); + if ( maxlen < len ) maxlen = len; + } + + char *ref = faidx_fetch_seq(args->fai, (char*)bcf_seqname(args->hdr,line), line->pos, line->pos+maxlen-1, &len); + if ( !ref ) error("faidx_fetch_seq failed at %s:%d\n", bcf_seqname(args->hdr,line),line->pos+1); + replace_iupac_codes(ref,len); + + args->nref.tot++; + + // is the REF different? + if ( !strncasecmp(line->d.allele[0],ref,reflen) ) { free(ref); return; } + + // is the REF allele missing or N? + if ( reflen==1 && (line->d.allele[0][0]=='.' || line->d.allele[0][0]=='N' || line->d.allele[0][0]=='n') ) + { + line->d.allele[0][0] = ref[0]; + args->nref.set++; + free(ref); + bcf_update_alleles(args->hdr,line,(const char**)line->d.allele,line->n_allele); + return; + } + + // does REF contain non-standard bases? + if ( replace_iupac_codes(line->d.allele[0],strlen(line->d.allele[0])) ) + { + args->nref.set++; + bcf_update_alleles(args->hdr,line,(const char**)line->d.allele,line->n_allele); + if ( !strncasecmp(line->d.allele[0],ref,reflen) ) { free(ref); return; } + } + + // is it swapped? + for (i=1; in_allele; i++) + { + int len = strlen(line->d.allele[i]); + if ( !strncasecmp(line->d.allele[i],ref,len) ) break; + } + + kstring_t str = {0,0,0}; + if ( i==line->n_allele ) + { + // none of the alternate alleles matches the reference + if ( line->n_allele>1 ) + args->nref.set++; + else + args->nref.swap++; + + kputs(line->d.allele[0],&str); + kputc(',',&str); + for (i=1; in_allele; i++) + { + kputs(line->d.allele[i],&str); + kputc(',',&str); + } + kputc(ref[0],&str); + bcf_update_alleles_str(args->hdr,line,str.s); + str.l = 0; + } + else + args->nref.swap++; + free(ref); + + // swap the alleles + int j; + kputs(line->d.allele[i],&str); + for (j=1; jd.allele[j],&str); + } + kputc(',',&str); + kputs(line->d.allele[0],&str); + for (j=i+1; jn_allele; j++) + { + kputc(',',&str); + kputs(line->d.allele[j],&str); + } + bcf_update_alleles_str(args->hdr,line,str.s); + + // swap genotypes + int ntmp = args->ntmp_arr1 / sizeof(int32_t); // reuse tmp_arr declared as uint8_t + int ngts = bcf_get_genotypes(args->hdr, line, &args->tmp_arr1, &ntmp); + args->ntmp_arr1 = ntmp * sizeof(int32_t); + int32_t *gts = (int32_t*) args->tmp_arr1; + int ni = 0; + for (j=0; jhdr,line,gts,ngts); + + // update AC + int nac = bcf_get_info_int32(args->hdr, line, "AC", &args->tmp_arr1, &ntmp); + args->ntmp_arr1 = ntmp * sizeof(int32_t); + if ( i <= nac ) + { + int32_t *ac = (int32_t*)args->tmp_arr1; + ac[i-1] = ni; + bcf_update_info_int32(args->hdr, line, "AC", ac, nac); + } + + free(str.s); +} + +static void fix_dup_alt(args_t *args, bcf1_t *line) +{ + // update alleles, create a mapping between old and new indexes + hts_expand(uint8_t,line->n_allele,args->ntmp_arr1,args->tmp_arr1); + args->tmp_arr1[0] = 0; // ref always unchanged + + int i, j, nals = line->n_allele, nals_ori = line->n_allele; + for (i=1, j=1; in_allele; i++) + { + if ( strcmp(line->d.allele[0],line->d.allele[i]) ) + { + args->tmp_arr1[i] = j++; + continue; + } + args->tmp_arr1[i] = 0; + nals--; + } + for (i=1, j=1; in_allele; i++) + { + if ( !args->tmp_arr1[i] ) continue; + line->d.allele[j++] = line->d.allele[i]; + } + bcf_update_alleles(args->hdr, line, (const char**)line->d.allele, nals); + + + // update genotypes + int ntmp = args->ntmp_arr2 / sizeof(int32_t); // reuse tmp_arr declared as uint8_t + int ngts = bcf_get_genotypes(args->hdr, line, &args->tmp_arr2, &ntmp); + args->ntmp_arr2 = ntmp * sizeof(int32_t); + int32_t *gts = (int32_t*) args->tmp_arr2; + int changed = 0; + for (i=0; itmp_arr1[ial] ) continue; + int ial_new = ialtmp_arr1[ial] : 0; + gts[i] = bcf_gt_is_phased(gts[i]) ? bcf_gt_phased(ial_new) : bcf_gt_unphased(ial_new); + changed = 1; + } + if ( changed ) bcf_update_genotypes(args->hdr,line,gts,ngts); +} + +#define ERR_DUP_ALLELE -2 +#define ERR_REF_MISMATCH -1 +#define ERR_OK 0 +#define ERR_SYMBOLIC 1 +#define ERR_SPANNING_DELETION 2 + +static int realign(args_t *args, bcf1_t *line) +{ + bcf_unpack(line, BCF_UN_STR); + + // Sanity check REF + int i, nref, reflen = strlen(line->d.allele[0]); + char *ref = faidx_fetch_seq(args->fai, (char*)args->hdr->id[BCF_DT_CTG][line->rid].key, line->pos, line->pos+reflen-1, &nref); + if ( !ref ) error("faidx_fetch_seq failed at %s:%d\n", args->hdr->id[BCF_DT_CTG][line->rid].key, line->pos+1); + replace_iupac_codes(ref,nref); // any non-ACGT character in fasta ref is replaced with N + + // does VCF REF contain non-standard bases? + if ( has_non_acgtn(line->d.allele[0],reflen) ) + { + if ( args->check_ref==CHECK_REF_EXIT ) + error("Non-ACGTN reference allele at %s:%d .. REF_SEQ:'%s' vs VCF:'%s'\n", bcf_seqname(args->hdr,line),line->pos+1,ref,line->d.allele[0]); + if ( args->check_ref & CHECK_REF_WARN ) + fprintf(stderr,"NON_ACGTN_REF\t%s\t%d\t%s\n", bcf_seqname(args->hdr,line),line->pos+1,line->d.allele[0]); + free(ref); + return ERR_REF_MISMATCH; + } + if ( strcasecmp(ref,line->d.allele[0]) ) + { + if ( args->check_ref==CHECK_REF_EXIT ) + error("Reference allele mismatch at %s:%d .. REF_SEQ:'%s' vs VCF:'%s'\n", bcf_seqname(args->hdr,line),line->pos+1,ref,line->d.allele[0]); + if ( args->check_ref & CHECK_REF_WARN ) + fprintf(stderr,"REF_MISMATCH\t%s\t%d\t%s\n", bcf_seqname(args->hdr,line),line->pos+1,line->d.allele[0]); + free(ref); + return ERR_REF_MISMATCH; + } + free(ref); + ref = NULL; + + if ( line->n_allele == 1 ) return ERR_OK; // a REF + + // make a copy of each allele for trimming + hts_expand0(kstring_t,line->n_allele,args->ntmp_als,args->tmp_als); + kstring_t *als = args->tmp_als; + for (i=0; in_allele; i++) + { + if ( line->d.allele[i][0]=='<' ) return ERR_SYMBOLIC; // symbolic allele + if ( line->d.allele[i][0]=='*' ) return ERR_SPANNING_DELETION; // spanning deletion + if ( bcf_get_variant_type(line,i)==VCF_BND ) return ERR_SYMBOLIC; // breakend, not an error + if ( has_non_acgtn(line->d.allele[i],0) ) + { + if ( args->check_ref==CHECK_REF_EXIT ) + error("Non-ACGTN alternate allele at %s:%d .. REF_SEQ:'%s' vs VCF:'%s'\n", bcf_seqname(args->hdr,line),line->pos+1,ref,line->d.allele[i]); + if ( args->check_ref & CHECK_REF_WARN ) + fprintf(stderr,"NON_ACGTN_ALT\t%s\t%d\t%s\n", bcf_seqname(args->hdr,line),line->pos+1,line->d.allele[i]); + return ERR_REF_MISMATCH; + } + + als[i].l = 0; + kputs(line->d.allele[i], &als[i]); + + if ( i>0 && als[i].l==als[0].l && !strcasecmp(als[0].s,als[i].s) ) return ERR_DUP_ALLELE; + } + + // trim from right + int ori_pos = line->pos; + while (1) + { + // is the rightmost base identical in all alleles? + int min_len = als[0].l; + for (i=1; in_allele; i++) + { + if ( als[0].s[ als[0].l-1 ]!=als[i].s[ als[i].l-1 ] ) break; + if ( als[i].l < min_len ) min_len = als[i].l; + } + if ( i!=line->n_allele ) break; // there are differences, cannot be trimmed + if ( min_len<=1 && line->pos==0 ) break; + + int pad_from_left = 0; + for (i=0; in_allele; i++) // trim all alleles + { + als[i].l--; + if ( !als[i].l ) pad_from_left = 1; + } + if ( pad_from_left ) + { + int npad = line->pos >= args->aln_win ? args->aln_win : line->pos; + free(ref); + ref = faidx_fetch_seq(args->fai, (char*)args->hdr->id[BCF_DT_CTG][line->rid].key, line->pos-npad, line->pos-1, &nref); + if ( !ref ) error("faidx_fetch_seq failed at %s:%d\n", args->hdr->id[BCF_DT_CTG][line->rid].key, line->pos-npad+1); + replace_iupac_codes(ref,nref); + for (i=0; in_allele; i++) + { + ks_resize(&als[i], als[i].l + npad); + if ( als[i].l ) memmove(als[i].s+npad,als[i].s,als[i].l); + memcpy(als[i].s,ref,npad); + als[i].l += npad; + } + line->pos -= npad; + } + } + free(ref); + + // trim from left + int ntrim_left = 0; + while (1) + { + // is the first base identical in all alleles? + int min_len = als[0].l - ntrim_left; + for (i=1; in_allele; i++) + { + if ( als[0].s[ntrim_left]!=als[i].s[ntrim_left] ) break; + if ( min_len > als[i].l - ntrim_left ) min_len = als[i].l - ntrim_left; + } + if ( i!=line->n_allele || min_len<=1 ) break; // there are differences, cannot be trimmed + ntrim_left++; + } + if ( ntrim_left ) + { + for (i=0; in_allele; i++) + { + memmove(als[i].s,als[i].s+ntrim_left,als[i].l-ntrim_left); + als[i].l -= ntrim_left; + } + line->pos += ntrim_left; + } + + // Have the alleles changed? + als[0].s[ als[0].l ] = 0; // in order for strcmp to work + if ( ori_pos==line->pos && !strcasecmp(line->d.allele[0],als[0].s) ) return ERR_OK; + + // Create new block of alleles and update + args->tmp_als_str.l = 0; + for (i=0; in_allele; i++) + { + if (i>0) kputc(',',&args->tmp_als_str); + kputsn(als[i].s,als[i].l,&args->tmp_als_str); + } + args->tmp_als_str.s[ args->tmp_als_str.l ] = 0; + bcf_update_alleles_str(args->hdr,line,args->tmp_als_str.s); + args->nchanged++; + + return ERR_OK; +} + +static void split_info_numeric(args_t *args, bcf1_t *src, bcf_info_t *info, int ialt, bcf1_t *dst) +{ + #define BRANCH_NUMERIC(type,type_t) \ + { \ + const char *tag = bcf_hdr_int2id(args->hdr,BCF_DT_ID,info->key); \ + int ntmp = args->ntmp_arr1 / sizeof(type_t); \ + int ret = bcf_get_info_##type(args->hdr,src,tag,&args->tmp_arr1,&ntmp); \ + args->ntmp_arr1 = ntmp * sizeof(type_t); \ + assert( ret>0 ); \ + type_t *vals = (type_t*) args->tmp_arr1; \ + int len = bcf_hdr_id2length(args->hdr,BCF_HL_INFO,info->key); \ + if ( len==BCF_VL_A ) \ + { \ + if ( ret!=src->n_allele-1 ) \ + error("Error: wrong number of fields in INFO/%s at %s:%d, expected %d, found %d\n", \ + tag,bcf_seqname(args->hdr,src),src->pos+1,src->n_allele-1,ret); \ + bcf_update_info_##type(args->hdr,dst,tag,vals+ialt,1); \ + } \ + else if ( len==BCF_VL_R ) \ + { \ + if ( ret!=src->n_allele ) \ + error("Error: wrong number of fields in INFO/%s at %s:%d, expected %d, found %d\n", \ + tag,bcf_seqname(args->hdr,src),src->pos+1,src->n_allele,ret); \ + if ( ialt!=0 ) vals[1] = vals[ialt+1]; \ + bcf_update_info_##type(args->hdr,dst,tag,vals,2); \ + } \ + else if ( len==BCF_VL_G ) \ + { \ + if ( ret!=src->n_allele*(src->n_allele+1)/2 ) \ + error("Error: wrong number of fields in INFO/%s at %s:%d, expected %d, found %d\n", \ + tag,bcf_seqname(args->hdr,src),src->pos+1,src->n_allele*(src->n_allele+1)/2,ret); \ + if ( ialt!=0 ) \ + { \ + vals[1] = vals[bcf_alleles2gt(0,ialt+1)]; \ + vals[2] = vals[bcf_alleles2gt(ialt+1,ialt+1)]; \ + } \ + bcf_update_info_##type(args->hdr,dst,tag,vals,3); \ + } \ + else \ + bcf_update_info_##type(args->hdr,dst,tag,vals,ret); \ + } + switch (bcf_hdr_id2type(args->hdr,BCF_HL_INFO,info->key)) + { + case BCF_HT_INT: BRANCH_NUMERIC(int32, int32_t); break; + case BCF_HT_REAL: BRANCH_NUMERIC(float, float); break; + } + #undef BRANCH_NUMERIC +} +// Find n-th field in a comma-separated list and move it to dst. +// The memory areas may overlap. +#define STR_MOVE_NTH(dst,src,end,nth,len) \ +{ \ + char *ss = src, *se = src; \ + int j = 0; \ + while ( *se && se<(end) ) \ + { \ + if ( *se==',' ) \ + { \ + if ( j==nth ) break; \ + j++; \ + ss = se+1; \ + } \ + se++; \ + } \ + if ( j==nth ) \ + { \ + int n = se - ss; \ + memmove((dst),ss,n); \ + src = se; \ + len += n; \ + } \ + else len = -1; \ +} +static void split_info_string(args_t *args, bcf1_t *src, bcf_info_t *info, int ialt, bcf1_t *dst) +{ + const char *tag = bcf_hdr_int2id(args->hdr,BCF_DT_ID,info->key); + int ret = bcf_get_info_string(args->hdr,src,tag,&args->tmp_arr1,&args->ntmp_arr1); + assert( ret>0 ); + + kstring_t str; + str.m = args->ntmp_arr1; + str.l = ret; + str.s = (char*) args->tmp_arr1; + + int len = bcf_hdr_id2length(args->hdr,BCF_HL_INFO,info->key); + if ( len==BCF_VL_A ) + { + char *tmp = str.s; + int len = 0; + STR_MOVE_NTH(str.s,tmp,str.s+str.l,ialt,len); + if ( len<0 ) return; // wrong number of fields: skip + str.s[len] = 0; + bcf_update_info_string(args->hdr,dst,tag,str.s); + } + else if ( len==BCF_VL_R ) + { + char *tmp = str.s; + int len = 0; + STR_MOVE_NTH(str.s,tmp,str.s+str.l,0,len); + str.s[len]=','; tmp++; len++; + STR_MOVE_NTH(&str.s[len],tmp,str.s+str.l,ialt,len); + if ( len<0 ) return; // wrong number of fields: skip + str.s[len] = 0; + bcf_update_info_string(args->hdr,dst,tag,str.s); + } + else if ( len==BCF_VL_G ) + { + int i0a = bcf_alleles2gt(0,ialt+1), iaa = bcf_alleles2gt(ialt+1,ialt+1); + char *tmp = str.s; + int len = 0; + STR_MOVE_NTH(str.s,tmp,str.s+str.l,0,len); + str.s[len]=','; tmp++; len++; + STR_MOVE_NTH(&str.s[len],tmp,str.s+str.l,i0a-1,len); + if ( len<0 ) return; // wrong number of fields: skip + str.s[len]=','; tmp++; len++; + STR_MOVE_NTH(&str.s[len],tmp,str.s+str.l,iaa-i0a-1,len); + if ( len<0 ) return; // wrong number of fields: skip + str.s[len] = 0; + bcf_update_info_string(args->hdr,dst,tag,str.s); + } + else + bcf_update_info_string(args->hdr,dst,tag,str.s); +} +static void split_info_flag(args_t *args, bcf1_t *src, bcf_info_t *info, int ialt, bcf1_t *dst) +{ + const char *tag = bcf_hdr_int2id(args->hdr,BCF_DT_ID,info->key); + int ret = bcf_get_info_flag(args->hdr,src,tag,&args->tmp_arr1,&args->ntmp_arr1); + bcf_update_info_flag(args->hdr,dst,tag,NULL,ret); +} + +static void split_format_genotype(args_t *args, bcf1_t *src, bcf_fmt_t *fmt, int ialt, bcf1_t *dst) +{ + int ntmp = args->ntmp_arr1 / 4; + int ngts = bcf_get_genotypes(args->hdr,src,&args->tmp_arr1,&ntmp); + args->ntmp_arr1 = ntmp * 4; + assert( ngts >0 ); + + int32_t *gt = (int32_t*) args->tmp_arr1; + int i, j, nsmpl = bcf_hdr_nsamples(args->hdr); + ngts /= nsmpl; + for (i=0; ihdr,dst,args->tmp_arr1,ngts*nsmpl); +} +static void split_format_numeric(args_t *args, bcf1_t *src, bcf_fmt_t *fmt, int ialt, bcf1_t *dst) +{ + #define BRANCH_NUMERIC(type,type_t,is_vector_end,set_vector_end) \ + { \ + const char *tag = bcf_hdr_int2id(args->hdr,BCF_DT_ID,fmt->id); \ + int ntmp = args->ntmp_arr1 / sizeof(type_t); \ + int nvals = bcf_get_format_##type(args->hdr,src,tag,&args->tmp_arr1,&ntmp); \ + args->ntmp_arr1 = ntmp * sizeof(type_t); \ + assert( nvals>0 ); \ + type_t *vals = (type_t *) args->tmp_arr1; \ + int len = bcf_hdr_id2length(args->hdr,BCF_HL_FMT,fmt->id); \ + int i, nsmpl = bcf_hdr_nsamples(args->hdr); \ + if ( nvals==nsmpl ) /* all values are missing */ \ + { \ + bcf_update_format_##type(args->hdr,dst,tag,vals,nsmpl); \ + return; \ + } \ + if ( len==BCF_VL_A ) \ + { \ + if ( nvals!=(src->n_allele-1)*nsmpl ) \ + error("Error: wrong number of fields in FMT/%s at %s:%d, expected %d, found %d\n", \ + tag,bcf_seqname(args->hdr,src),src->pos+1,(src->n_allele-1)*nsmpl,nvals); \ + nvals /= nsmpl; \ + type_t *src_vals = vals, *dst_vals = vals; \ + for (i=0; ihdr,dst,tag,vals,nsmpl); \ + } \ + else if ( len==BCF_VL_R ) \ + { \ + if ( nvals!=src->n_allele*nsmpl ) \ + error("Error: wrong number of fields in FMT/%s at %s:%d, expected %d, found %d\n", \ + tag,bcf_seqname(args->hdr,src),src->pos+1,src->n_allele*nsmpl,nvals); \ + nvals /= nsmpl; \ + type_t *src_vals = vals, *dst_vals = vals; \ + for (i=0; ihdr,dst,tag,vals,nsmpl*2); \ + } \ + else if ( len==BCF_VL_G ) \ + { \ + if ( nvals!=src->n_allele*(src->n_allele+1)/2*nsmpl && nvals!=src->n_allele*nsmpl ) \ + error("Error at %s:%d, the tag %s has wrong number of fields\n", bcf_seqname(args->hdr,src),src->pos+1,bcf_hdr_int2id(args->hdr,BCF_DT_ID,fmt->id)); \ + nvals /= nsmpl; \ + int all_haploid = nvals==src->n_allele ? 1 : 0; \ + type_t *src_vals = vals, *dst_vals = vals; \ + for (i=0; ihdr,dst,tag,vals,all_haploid ? nsmpl*2 : nsmpl*3); \ + } \ + else \ + bcf_update_format_##type(args->hdr,dst,tag,vals,nvals); \ + } + switch (bcf_hdr_id2type(args->hdr,BCF_HL_FMT,fmt->id)) + { + case BCF_HT_INT: BRANCH_NUMERIC(int32, int32_t, src_vals[j]==bcf_int32_vector_end, dst_vals[2]=bcf_int32_vector_end); break; + case BCF_HT_REAL: BRANCH_NUMERIC(float, float, bcf_float_is_vector_end(src_vals[j]), bcf_float_set_vector_end(dst_vals[2])); break; + } + #undef BRANCH_NUMERIC +} +static void squeeze_format_char(char *str, int src_blen, int dst_blen, int n) +{ + int i, isrc = 0, idst = 0; + for (i=0; ihdr,BCF_DT_ID,fmt->id); + int ret = bcf_get_format_char(args->hdr,src,tag,&args->tmp_arr1,&args->ntmp_arr1); + assert( ret>0 ); + + kstring_t str; + str.m = args->ntmp_arr1; + str.l = ret; + str.s = (char*) args->tmp_arr1; + + int nsmpl = bcf_hdr_nsamples(args->hdr); + int len = bcf_hdr_id2length(args->hdr,BCF_HL_FMT,fmt->id); + if ( len==BCF_VL_A ) + { + int i, blen = ret/nsmpl, maxlen = 0; + char *ptr = str.s; + for (i=0; ihdr,dst,tag,str.s,nsmpl*maxlen); + } + else if ( len==BCF_VL_R ) + { + int i, blen = ret/nsmpl, maxlen = 0; + char *ptr = str.s; + for (i=0; ihdr,dst,tag,str.s,nsmpl*maxlen); + } + else if ( len==BCF_VL_G ) + { + int i, blen = ret/nsmpl, maxlen = 0, i0a = bcf_alleles2gt(0,ialt+1), iaa = bcf_alleles2gt(ialt+1,ialt+1); + char *ptr = str.s; + for (i=0; in_allele*(src->n_allele+1)/2 && nfields!=src->n_allele ) + error("Error: wrong number of fields in FMT/%s at %s:%d, expected %d or %d, found %d\n", + tag,bcf_seqname(args->hdr,src),src->pos+1,src->n_allele*(src->n_allele+1)/2,src->n_allele,nfields); + + int len = 0; + if ( nfields==src->n_allele ) // haploid + { + char *tmp = ptr; + STR_MOVE_NTH(&ptr[len],tmp,ptr+blen,0,len); + ptr[len]=','; tmp++; len++; + STR_MOVE_NTH(&ptr[len],tmp,ptr+blen,ialt,len); + if ( len<0 ) return; // wrong number of fields: skip + } + else // diploid + { + char *tmp = ptr; + STR_MOVE_NTH(&ptr[len],tmp,ptr+blen,0,len); + ptr[len]=','; tmp++; len++; + STR_MOVE_NTH(&ptr[len],tmp,ptr+blen,i0a-1,len); + if ( len<0 ) return; // wrong number of fields: skip + ptr[len]=','; tmp++; len++; + STR_MOVE_NTH(&ptr[len],tmp,ptr+blen,iaa-i0a-1,len); + if ( len<0 ) return; // wrong number of fields: skip + } + if ( maxlen < len ) maxlen = len; + ptr += blen; + } + if ( maxlenhdr,dst,tag,str.s,nsmpl*maxlen); + } + else + bcf_update_format_char(args->hdr,dst,tag,str.s,str.l); +} + + +static void split_multiallelic_to_biallelics(args_t *args, bcf1_t *line) +{ + int i; + + bcf_unpack(line, BCF_UN_ALL); + + // Init the target biallelic lines + args->ntmp_lines = line->n_allele-1; + if ( args->mtmp_lines < args->ntmp_lines ) + { + args->tmp_lines = (bcf1_t **)realloc(args->tmp_lines,sizeof(bcf1_t*)*args->ntmp_lines); + for (i=args->mtmp_lines; intmp_lines; i++) + args->tmp_lines[i] = NULL; + args->mtmp_lines = args->ntmp_lines; + } + kstring_t tmp = {0,0,0}; + kputs(line->d.allele[0], &tmp); + kputc(',', &tmp); + int rlen = tmp.l; + int gt_id = bcf_hdr_id2int(args->hdr,BCF_DT_ID,"GT"); + for (i=0; intmp_lines; i++) // for each ALT allele + { + if ( !args->tmp_lines[i] ) args->tmp_lines[i] = bcf_init1(); + bcf1_t *dst = args->tmp_lines[i]; + bcf_clear(dst); + + dst->rid = line->rid; + dst->pos = line->pos; + dst->qual = line->qual; + + // Not quite sure how to handle IDs, they can be assigned to a specific + // ALT. For now we leave the ID unchanged for all. + bcf_update_id(args->hdr, dst, line->d.id ? line->d.id : "."); + + tmp.l = rlen; + kputs(line->d.allele[i+1],&tmp); + bcf_update_alleles_str(args->hdr,dst,tmp.s); + + if ( line->d.n_flt ) bcf_update_filter(args->hdr, dst, line->d.flt, line->d.n_flt); + + int j; + for (j=0; jn_info; j++) + { + bcf_info_t *info = &line->d.info[j]; + int type = bcf_hdr_id2type(args->hdr,BCF_HL_INFO,info->key); + if ( type==BCF_HT_INT || type==BCF_HT_REAL ) split_info_numeric(args, line, info, i, dst); + else if ( type==BCF_HT_FLAG ) split_info_flag(args, line, info, i, dst); + else split_info_string(args, line, info, i, dst); + } + + dst->n_sample = line->n_sample; + for (j=0; jn_fmt; j++) + { + bcf_fmt_t *fmt = &line->d.fmt[j]; + int type = bcf_hdr_id2type(args->hdr,BCF_HL_FMT,fmt->id); + if ( fmt->id==gt_id ) split_format_genotype(args, line, fmt, i, dst); + else if ( type==BCF_HT_INT || type==BCF_HT_REAL ) split_format_numeric(args, line, fmt, i, dst); + else split_format_string(args, line, fmt, i, dst); + } + } + free(tmp.s); +} + +// Enlarge FORMAT array containing nsmpl samples each with nals_ori values +// to accommodate nvals values for each sample, filling the gaps with missing +// values. Works also for INFO arrays, with nsmpl set to 1. +#define ENLARGE_ARRAY(type_t,set_missing,arr,narr_bytes,nsmpl,nvals_ori,nvals) \ +{ \ + int nbytes_new = (nsmpl)*(nvals)*sizeof(type_t); \ + hts_expand(uint8_t,nbytes_new,narr_bytes,arr); \ + int ismpl, k; \ + for (ismpl=nsmpl-1; ismpl>=0; ismpl--) \ + { \ + type_t *dst_ptr = ((type_t*)arr) + ismpl*(nvals); \ + type_t *src_ptr = ((type_t*)arr) + ismpl*nvals_ori; \ + memmove(dst_ptr,src_ptr,sizeof(type_t)*nvals_ori); \ + for (k=nvals_ori; khdr,BCF_DT_ID,info->key); \ + int ntmp = args->ntmp_arr1 / sizeof(type_t); \ + int nvals_ori = bcf_get_info_##type(args->hdr,lines[0],tag,&args->tmp_arr1,&ntmp); \ + args->ntmp_arr1 = ntmp * sizeof(type_t); \ + assert( nvals_ori>0 ); \ + type_t *vals = (type_t*) args->tmp_arr1, *vals2; \ + int i,k,len = bcf_hdr_id2length(args->hdr,BCF_HL_INFO,info->key); \ + if ( len==BCF_VL_A ) \ + { \ + if (nvals_ori!=lines[0]->n_allele - 1) \ + error("vcfnorm: number of fields in first record at position %s:%d for INFO tag %s not as expected [found: %d vs expected:%d]\n", bcf_seqname(args->hdr,lines[0]),lines[0]->pos+1, tag, nvals_ori, lines[0]->n_allele-1); \ + int nvals = dst->n_allele - 1; \ + ENLARGE_ARRAY(type_t,set_missing,args->tmp_arr1,args->ntmp_arr1,1,nvals_ori,nvals); \ + vals = (type_t*) args->tmp_arr1; \ + for (i=1; intmp_arr2 / sizeof(type_t); \ + int nvals2 = bcf_get_info_##type(args->hdr,lines[i],tag,&args->tmp_arr2,&ntmp2); \ + if (nvals2<0) continue; /* info tag does not exist in this record, skip */ \ + args->ntmp_arr2 = ntmp2 * sizeof(type_t); \ + if (nvals2!=lines[i]->n_allele-1) \ + error("vcfnorm: could not merge INFO tag %s at position %s:%d\n", tag, bcf_seqname(args->hdr,lines[i]),lines[i]->pos+1); \ + vals2 = (type_t*) args->tmp_arr2; \ + for (k=0; kmaps[i].map[k+1] - 1 ] = vals2[k]; \ + } \ + } \ + bcf_update_info_##type(args->hdr,dst,tag,args->tmp_arr1,nvals); \ + } \ + else if ( len==BCF_VL_R ) \ + { \ + if (nvals_ori!=lines[0]->n_allele) \ + error("vcfnorm: number of fields in first record at position %s:%d for INFO tag %s not as expected [found: %d vs expected:%d]\n", bcf_seqname(args->hdr,lines[0]),lines[0]->pos+1, tag, nvals_ori, lines[0]->n_allele); \ + int nvals = dst->n_allele; \ + ENLARGE_ARRAY(type_t,set_missing,args->tmp_arr1,args->ntmp_arr1,1,nvals_ori,nvals); \ + vals = (type_t*) args->tmp_arr1; \ + for (i=1; intmp_arr2 / sizeof(type_t); \ + int nvals2 = bcf_get_info_##type(args->hdr,lines[i],tag,&args->tmp_arr2,&ntmp2); \ + if (nvals2<0) continue; /* info tag does not exist in this record, skip */ \ + args->ntmp_arr2 = ntmp2 * sizeof(type_t); \ + if (nvals2!=lines[i]->n_allele) \ + error("vcfnorm: could not merge INFO tag %s at position %s:%d\n", tag, bcf_seqname(args->hdr,lines[i]),lines[i]->pos+1); \ + vals2 = (type_t*) args->tmp_arr2; \ + for (k=0; kmaps[i].map[k] ] = vals2[k]; \ + } \ + } \ + bcf_update_info_##type(args->hdr,dst,tag,args->tmp_arr1,nvals); \ + } \ + else if ( len==BCF_VL_G ) \ + { \ + /* expecting diploid gt in INFO */ \ + if (nvals_ori!=lines[0]->n_allele*(lines[0]->n_allele+1)/2) { \ + fprintf(stderr, "todo: merge Number=G INFO fields for haploid sites\n"); \ + error("vcfnorm: number of fields in first record at position %s:%d for INFO tag %s not as expected [found: %d vs expected:%d]\n", bcf_seqname(args->hdr,lines[0]),lines[0]->pos+1, tag, nvals_ori, lines[0]->n_allele*(lines[0]->n_allele+1)/2); \ + } \ + int nvals = dst->n_allele*(dst->n_allele+1)/2; \ + ENLARGE_ARRAY(type_t,set_missing,args->tmp_arr1,args->ntmp_arr1,1,nvals_ori,nvals); \ + vals = (type_t*) args->tmp_arr1; \ + for (i=1; intmp_arr2 / sizeof(type_t); \ + int nvals2 = bcf_get_info_##type(args->hdr,lines[i],tag,&args->tmp_arr2,&ntmp2); \ + if (nvals2<0) continue; /* info tag does not exist in this record, skip */ \ + args->ntmp_arr2 = ntmp2 * sizeof(type_t); \ + if (nvals2!=lines[i]->n_allele*(lines[i]->n_allele+1)/2) \ + error("vcfnorm: could not merge INFO tag %s at position %s:%d\n", tag, bcf_seqname(args->hdr,lines[i]),lines[i]->pos+1); \ + vals2 = (type_t*) args->tmp_arr2; \ + int ia,ib; \ + k = 0; \ + for (ia=0; ian_allele; ia++) \ + { \ + for (ib=0; ib<=ia; ib++) \ + { \ + if ( is_vector_end ) break; \ + int l = bcf_alleles2gt(args->maps[i].map[ia],args->maps[i].map[ib]); \ + vals[l] = vals2[k]; \ + k++; \ + } \ + } \ + } \ + bcf_update_info_##type(args->hdr,dst,tag,args->tmp_arr1,nvals); \ + } \ + else \ + bcf_update_info_##type(args->hdr,dst,tag,vals,nvals_ori); \ + } + switch (bcf_hdr_id2type(args->hdr,BCF_HL_INFO,info->key)) + { + case BCF_HT_INT: BRANCH_NUMERIC(int32, int32_t, dst_ptr[k]=bcf_int32_missing, vals2[k]==bcf_int32_vector_end); break; + case BCF_HT_REAL: BRANCH_NUMERIC(float, float, bcf_float_set_missing(dst_ptr[k]), bcf_float_is_vector_end(vals2[k])); break; + } + #undef BRANCH_NUMERIC +} +static void merge_info_flag(args_t *args, bcf1_t **lines, int nlines, bcf_info_t *info, bcf1_t *dst) +{ + const char *tag = bcf_hdr_int2id(args->hdr,BCF_DT_ID,info->key); + int ret = bcf_get_info_flag(args->hdr,lines[0],tag,&args->tmp_arr1,&args->ntmp_arr1); + bcf_update_info_flag(args->hdr,dst,tag,NULL,ret); +} +int copy_string_field(char *src, int isrc, int src_len, kstring_t *dst, int idst); // see vcfmerge.c +static void merge_info_string(args_t *args, bcf1_t **lines, int nlines, bcf_info_t *info, bcf1_t *dst) +{ + const char *tag = bcf_hdr_int2id(args->hdr,BCF_DT_ID,info->key); + + kstring_t str; + str.m = args->ntmp_arr1; + str.l = 0; + str.s = (char*) args->tmp_arr1; + + int i, j, len = bcf_hdr_id2length(args->hdr,BCF_HL_INFO,info->key); + if ( len==BCF_VL_A || len==BCF_VL_R ) + { + int jfrom = len==BCF_VL_A ? 1 : 0; + kputc('.',&str); + for (i=jfrom+1; in_allele; i++) kputs(",.",&str); + for (i=0; ihdr,lines[i],tag); + if (!src) continue; + for (j=jfrom; jn_allele; j++) + copy_string_field((char*)src->vptr, j-jfrom, src->len, &str, args->maps[i].map[j]-jfrom); + } + str.s[str.l] = 0; + args->tmp_arr1 = (uint8_t*) str.s; + args->ntmp_arr1 = str.m; + bcf_update_info_string(args->hdr,dst,tag,str.s); + } + else if ( len==BCF_VL_G ) + { + int ngts = dst->n_allele*(dst->n_allele+1)/2; + kputc('.',&str); + for (i=1; ihdr,lines[i],tag); + if (!src) continue; + int iori, jori, kori = 0; + for (iori=0; iorin_allele; iori++) + { + int inew = args->maps[i].map[iori]; + for (jori=0; jori<=iori; jori++) + { + int jnew = args->maps[i].map[jori]; + int knew = bcf_alleles2gt(inew,jnew); + copy_string_field((char*)src->vptr,kori,src->len,&str,knew); + kori++; + } + } + } + str.s[str.l] = 0; + args->tmp_arr1 = (uint8_t*) str.s; + args->ntmp_arr1 = str.m; + bcf_update_info_string(args->hdr,dst,tag,str.s); + } + else + { + bcf_get_info_string(args->hdr,lines[0],tag,&args->tmp_arr1,&args->ntmp_arr1); + bcf_update_info_string(args->hdr,dst,tag,args->tmp_arr1); + } +} +static void merge_format_genotype(args_t *args, bcf1_t **lines, int nlines, bcf_fmt_t *fmt, bcf1_t *dst) +{ + int ntmp = args->ntmp_arr1 / 4; + int ngts = bcf_get_genotypes(args->hdr,lines[0],&args->tmp_arr1,&ntmp); + args->ntmp_arr1 = ntmp * 4; + assert( ngts >0 ); + + int nsmpl = bcf_hdr_nsamples(args->hdr); + ngts /= nsmpl; + + int i, j, k; + for (i=1; intmp_arr2 / 4; + int ngts2 = bcf_get_genotypes(args->hdr,lines[i],&args->tmp_arr2,&ntmp2); + args->ntmp_arr2 = ntmp2 * 4; + ngts2 /= nsmpl; + if ( ngts!=ngts2 ) error("Error at %s:%d: cannot combine diploid with haploid genotype\n", bcf_seqname(args->hdr,lines[i]),lines[i]->pos+1); + + int32_t *gt = (int32_t*) args->tmp_arr1; + int32_t *gt2 = (int32_t*) args->tmp_arr2; + for (j=0; j=args->maps[i].nals ) error("Error at %s:%d: incorrect allele index %d\n",bcf_seqname(args->hdr,lines[i]),lines[i]->pos+1,ial); + gt[k] = bcf_gt_unphased( args->maps[i].map[ial] ) | bcf_gt_is_phased(gt[k]); + } + } + gt += ngts; + gt2 += ngts; + } + } + bcf_update_genotypes(args->hdr,dst,args->tmp_arr1,ngts*nsmpl); +} +static int diploid_to_haploid(int size, int nsmpl, int nals, uint8_t *vals) +{ + int i, dsrc = size*nals*(nals+1)/2, ddst = size*nals; + uint8_t *src_ptr = vals + dsrc, *dst_ptr = vals + ddst; + for (i=1; ihdr,BCF_DT_ID,fmt->id); \ + int ntmp = args->ntmp_arr1 / sizeof(type_t); \ + int nvals_ori = bcf_get_format_##type(args->hdr,lines[0],tag,&args->tmp_arr1,&ntmp); \ + args->ntmp_arr1 = ntmp * sizeof(type_t); \ + assert( nvals_ori>0 ); \ + type_t *vals2, *vals = (type_t *) args->tmp_arr1; \ + int len = bcf_hdr_id2length(args->hdr,BCF_HL_FMT,fmt->id); \ + int i, j, k, nsmpl = bcf_hdr_nsamples(args->hdr); \ + nvals_ori /= nsmpl; \ + if ( len==BCF_VL_A ) \ + { \ + int nvals = dst->n_allele - 1; \ + ENLARGE_ARRAY(type_t,set_missing,args->tmp_arr1,args->ntmp_arr1,nsmpl,nvals_ori,nvals); \ + for (i=1; intmp_arr2 / sizeof(type_t); \ + int nvals2 = bcf_get_format_##type(args->hdr,lines[i],tag,&args->tmp_arr2,&ntmp2); \ + if (nvals2<0) continue; /* format tag does not exist in this record, skip */ \ + args->ntmp_arr2 = ntmp2 * sizeof(type_t); \ + nvals2 /= nsmpl; \ + if (nvals2!=lines[i]->n_allele-1) \ + error("vcfnorm: could not merge FORMAT tag %s at position %s:%d\n", tag, bcf_seqname(args->hdr,lines[i]),lines[i]->pos+1); \ + vals = (type_t*) args->tmp_arr1; \ + vals2 = (type_t*) args->tmp_arr2; \ + for (j=0; jmaps[i].map[k+1] - 1 ] = vals2[k]; \ + } \ + vals += nvals; \ + vals2 += nvals2; \ + } \ + } \ + bcf_update_format_##type(args->hdr,dst,tag,args->tmp_arr1,nvals*nsmpl); \ + } \ + else if ( len==BCF_VL_R ) \ + { \ + int nvals = dst->n_allele; \ + ENLARGE_ARRAY(type_t,set_missing,args->tmp_arr1,args->ntmp_arr1,nsmpl,nvals_ori,nvals); \ + for (i=1; intmp_arr2 / sizeof(type_t); \ + int nvals2 = bcf_get_format_##type(args->hdr,lines[i],tag,&args->tmp_arr2,&ntmp2); \ + if (nvals2<0) continue; /* format tag does not exist in this record, skip */ \ + args->ntmp_arr2 = ntmp2 * sizeof(type_t); \ + nvals2 /= nsmpl; \ + if (nvals2!=lines[i]->n_allele) \ + error("vcfnorm: could not merge FORMAT tag %s at position %s:%d\n", tag, bcf_seqname(args->hdr,lines[i]),lines[i]->pos+1); \ + vals = (type_t*) args->tmp_arr1; \ + vals2 = (type_t*) args->tmp_arr2; \ + for (j=0; jmaps[i].map[k] ] = vals2[k]; \ + } \ + vals += nvals; \ + vals2 += nvals2; \ + } \ + } \ + bcf_update_format_##type(args->hdr,dst,tag,args->tmp_arr1,nvals*nsmpl); \ + } \ + else if ( len==BCF_VL_G ) \ + { \ + /* which samples are diploid */ \ + memset(args->diploid,0,nsmpl); \ + int all_haploid = 1; \ + if ( nvals_ori > lines[0]->n_allele ) /* line possibly diploid */ \ + { \ + vals2 = (type_t*) args->tmp_arr1; \ + int ndiploid = lines[0]->n_allele*(lines[0]->n_allele+1)/2; \ + for (i=0; idiploid[i] ) \ + { \ + for (k=0; kdiploid[i] = 1; all_haploid = 0; }\ + } \ + vals2 += nvals_ori; \ + } \ + } \ + int nvals = dst->n_allele*(dst->n_allele+1)/2; \ + ENLARGE_ARRAY(type_t,set_missing,args->tmp_arr1,args->ntmp_arr1,nsmpl,nvals_ori,nvals); \ + for (i=1; intmp_arr2 / sizeof(type_t); \ + int nvals2 = bcf_get_format_##type(args->hdr,lines[i],tag,&args->tmp_arr2,&ntmp2); \ + if (nvals2<0) continue; /* format tag does not exist in this record, skip */ \ + args->ntmp_arr2 = ntmp2 * sizeof(type_t); \ + nvals2 /= nsmpl; \ + int ndiploid = lines[i]->n_allele*(lines[i]->n_allele+1)/2; \ + int line_diploid = nvals2==ndiploid ? 1 : 0; \ + if (!(nvals2==1 || nvals2==lines[i]->n_allele || nvals2==lines[i]->n_allele*(lines[i]->n_allele+1)/2)) \ + error("vcfnorm: could not merge FORMAT tag %s at position %s:%d\n", tag, bcf_seqname(args->hdr,lines[i]),lines[i]->pos+1); \ + vals = (type_t*) args->tmp_arr1; \ + vals2 = (type_t*) args->tmp_arr2; \ + for (j=0; jdiploid[j] ) { args->diploid[j] = 1; all_haploid = 0; } \ + if ( !smpl_diploid ) \ + { \ + for (k=0; kn_allele; k++) vals[args->maps[i].map[k]] = vals2[k]; \ + } \ + else \ + { \ + k = 0; \ + int ia,ib; \ + for (ia=0; ian_allele; ia++) \ + { \ + for (ib=0; ib<=ia; ib++) \ + { \ + int l = bcf_alleles2gt(args->maps[i].map[ia],args->maps[i].map[ib]); \ + vals[l] = vals2[k]; \ + k++; \ + } \ + } \ + } \ + vals += nvals; \ + vals2 += nvals2; \ + } \ + } \ + if ( all_haploid ) \ + nvals = diploid_to_haploid(sizeof(type_t),nsmpl,dst->n_allele,args->tmp_arr1); \ + else \ + {\ + k = dst->n_allele;\ + vals2 = (type_t*) args->tmp_arr1;\ + for (i=0; idiploid[i] ) set_vector_end;\ + vals2 += nvals;\ + }\ + }\ + bcf_update_format_##type(args->hdr,dst,tag,args->tmp_arr1,nvals*nsmpl); \ + } \ + else \ + bcf_update_format_##type(args->hdr,dst,tag,args->tmp_arr1,nvals_ori*nsmpl); \ + } + switch (bcf_hdr_id2type(args->hdr,BCF_HL_FMT,fmt->id)) + { + case BCF_HT_INT: BRANCH_NUMERIC(int32, int32_t, dst_ptr[k]=bcf_int32_missing, vals2[k]==bcf_int32_vector_end, vals2[k]=bcf_int32_vector_end); break; + case BCF_HT_REAL: BRANCH_NUMERIC(float, float, bcf_float_set_missing(dst_ptr[k]), bcf_float_is_vector_end(vals2[k]), bcf_float_set_vector_end(vals2[k])); break; + } + #undef BRANCH_NUMERIC +} +static void merge_format_string(args_t *args, bcf1_t **lines, int nlines, bcf_fmt_t *fmt, bcf1_t *dst) +{ + const char *tag = bcf_hdr_int2id(args->hdr,BCF_DT_ID,fmt->id); + + int i, j, k, len = bcf_hdr_id2length(args->hdr,BCF_HL_FMT,fmt->id); + if ( len!=BCF_VL_A && len!=BCF_VL_R && len!=BCF_VL_G ) + { + int nret = bcf_get_format_char(args->hdr,lines[0],tag,&args->tmp_arr1,&args->ntmp_arr1); + bcf_update_format_char(args->hdr,dst,tag,args->tmp_arr1,nret); + return; + } + + int nsmpl = bcf_hdr_nsamples(args->hdr); + for (i=0; itmp_str[i].l = 0; + + if ( len==BCF_VL_A || len==BCF_VL_R ) + { + int jfrom = len==BCF_VL_A ? 1 : 0; + for (i=0; itmp_str[i]; + kputc('.',tmp); + for (k=jfrom+1; kn_allele; k++) kputs(",.",tmp); + } + for (i=0; ihdr,lines[i],tag,&args->tmp_arr1,&args->ntmp_arr1); + if (nret<0) continue; /* format tag does not exist in this record, skip */ \ + nret /= nsmpl; + for (k=0; ktmp_str[k]; + char *src = (char*)args->tmp_arr1 + k*nret; + for (j=jfrom; jn_allele; j++) + copy_string_field(src, j-jfrom, nret, tmp, args->maps[i].map[j]-jfrom); + } + } + } + else if ( len==BCF_VL_G ) + { + hts_expand(uint8_t,nsmpl,args->ntmp_arr2,args->tmp_arr2); + uint8_t *haploid = args->tmp_arr2; + int nret = bcf_get_format_char(args->hdr,lines[0],tag,&args->tmp_arr1,&args->ntmp_arr1); + nret /= nsmpl; + for (i=0; itmp_arr1 + i*nret, *se = ss+nret; + int nfields = 1; + while ( *ss && ssn_allele ) + { + haploid[i] = 1; + nfields = dst->n_allele; + } + else if ( nfields==lines[0]->n_allele*(lines[0]->n_allele+1)/2 ) + { + haploid[i] = 0; + nfields = dst->n_allele*(dst->n_allele+1)/2; + } + else error("The field %s at %s:%d neither diploid nor haploid?\n", tag,bcf_seqname(args->hdr,dst),dst->pos+1); + + kstring_t *tmp = &args->tmp_str[i]; + kputc('.',tmp); + for (j=1; jhdr,lines[i],tag,&args->tmp_arr1,&args->ntmp_arr1); + if (nret<0) continue; /* format tag does not exist in this record, skip */ \ + nret /= nsmpl; + } + for (k=0; ktmp_str[k]; + char *src = (char*)args->tmp_arr1 + k*nret; + if ( haploid[k] ) + { + for (j=0; jn_allele; j++) + copy_string_field(src,j,nret, tmp, args->maps[i].map[j]); + } + else + { + int iori, jori, kori = 0; + for (iori=0; iorin_allele; iori++) + { + int inew = args->maps[i].map[iori]; + for (jori=0; jori<=iori; jori++) + { + int jnew = args->maps[i].map[jori]; + int knew = bcf_alleles2gt(inew,jnew); + copy_string_field(src,kori,nret,tmp,knew); + kori++; + } + } + } + } + } + } + kstring_t str; + str.m = args->ntmp_arr2; + str.l = 0; + str.s = (char*) args->tmp_arr2; + + int max_len = 0; + for (i=0; itmp_str[i].l ) max_len = args->tmp_str[i].l; + for (i=0; itmp_str[i]; + kputsn(tmp->s,tmp->l,&str); + for (j=tmp->l; jntmp_arr2 = str.m; + args->tmp_arr2 = (uint8_t*)str.s; + bcf_update_format_char(args->hdr,dst,tag,str.s,str.l); +} + +char **merge_alleles(char **a, int na, int *map, char **b, int *nb, int *mb); // see vcfmerge.c +static void merge_biallelics_to_multiallelic(args_t *args, bcf1_t *dst, bcf1_t **lines, int nlines) +{ + int i; + for (i=0; irid = lines[0]->rid; + dst->pos = lines[0]->pos; + + // take max for QUAL + bcf_float_set_missing(dst->qual); + for (i=0; iqual)) continue; + if (bcf_float_is_missing(dst->qual) || dst->qualqual) + dst->qual = lines[i]->qual; + } + + bcf_update_id(args->hdr, dst, lines[0]->d.id); + + // Merge and set the alleles, create a mapping from source allele indexes to dst idxs + hts_expand0(map_t,nlines,args->mmaps,args->maps); // a mapping for each line + args->nals = args->maps[0].nals = lines[0]->n_allele; + hts_expand(int,args->maps[0].nals,args->maps[0].mals,args->maps[0].map); + hts_expand(char*,args->nals,args->mals,args->als); + for (i=0; imaps[0].nals; i++) + { + args->maps[0].map[i] = i; + args->als[i] = strdup(lines[0]->d.allele[i]); + } + for (i=1; id.id[0]!='.' || lines[i]->d.id[1]) bcf_add_id(args->hdr, dst, lines[i]->d.id); + args->maps[i].nals = lines[i]->n_allele; + hts_expand(int,args->maps[i].nals,args->maps[i].mals,args->maps[i].map); + args->als = merge_alleles(lines[i]->d.allele, lines[i]->n_allele, args->maps[i].map, args->als, &args->nals, &args->mals); + if ( !args->als ) error("Failed to merge alleles at %s:%d\n", bcf_seqname(args->hdr,dst),dst->pos+1); + } + bcf_update_alleles(args->hdr, dst, (const char**)args->als, args->nals); + for (i=0; inals; i++) + { + free(args->als[i]); + args->als[i] = NULL; + } + + if ( lines[0]->d.n_flt ) bcf_update_filter(args->hdr, dst, lines[0]->d.flt, lines[0]->d.n_flt); + for (i=1; id.n_flt; j++) { + // if strict_filter, set FILTER to PASS if any site PASS + // otherwise accumulate FILTERs + if (lines[i]->d.flt[j] == bcf_hdr_id2int(args->hdr, BCF_DT_ID, "PASS")) { + if (args->strict_filter) { + bcf_update_filter(args->hdr, dst, lines[i]->d.flt, lines[i]->d.n_flt); + break; + } + else + continue; + } + bcf_add_filter(args->hdr, dst, lines[i]->d.flt[j]); + } + } + + // merge info + for (i=0; in_info; i++) + { + bcf_info_t *info = &lines[0]->d.info[i]; + int type = bcf_hdr_id2type(args->hdr,BCF_HL_INFO,info->key); + if ( type==BCF_HT_INT || type==BCF_HT_REAL ) merge_info_numeric(args, lines, nlines, info, dst); + else if ( type==BCF_HT_FLAG ) merge_info_flag(args, lines, nlines, info, dst); + else merge_info_string(args, lines, nlines, info, dst); + } + + // merge format + int gt_id = bcf_hdr_id2int(args->hdr,BCF_DT_ID,"GT"); + dst->n_sample = lines[0]->n_sample; + for (i=0; in_fmt; i++) + { + bcf_fmt_t *fmt = &lines[0]->d.fmt[i]; + int type = bcf_hdr_id2type(args->hdr,BCF_HL_FMT,fmt->id); + if ( fmt->id==gt_id ) merge_format_genotype(args, lines, nlines, fmt, dst); + else if ( type==BCF_HT_INT || type==BCF_HT_REAL ) merge_format_numeric(args, lines, nlines, fmt, dst); + else merge_format_string(args, lines, nlines, fmt, dst); + } +} + +#define SWAP(type_t, a, b) { type_t t = a; a = b; b = t; } +static void mrows_schedule(args_t *args, bcf1_t **line) +{ + int i,m; + if ( args->mrows_collapse==COLLAPSE_ANY // merge all record types together + || bcf_get_variant_types(*line)&VCF_SNP // SNP, put into alines + || bcf_get_variant_types(*line)==VCF_REF ) // ref + { + args->nalines++; + m = args->malines; + hts_expand(bcf1_t*,args->nalines,args->malines,args->alines); + for (i=m; imalines; i++) args->alines[i] = bcf_init1(); + SWAP(bcf1_t*, args->alines[args->nalines-1], *line); + } + else + { + args->nblines++; + m = args->mblines; + hts_expand(bcf1_t*,args->nblines,args->mblines,args->blines); + for (i=m; imblines; i++) args->blines[i] = bcf_init1(); + SWAP(bcf1_t*, args->blines[args->nblines-1], *line); + } +} +static int mrows_ready_to_flush(args_t *args, bcf1_t *line) +{ + if ( args->nalines && (args->alines[0]->rid!=line->rid || args->alines[0]->pos!=line->pos) ) return 1; + if ( args->nblines && (args->blines[0]->rid!=line->rid || args->blines[0]->pos!=line->pos) ) return 1; + return 0; +} +static bcf1_t *mrows_flush(args_t *args) +{ + if ( args->nblines && args->nalines==1 && bcf_get_variant_types(args->alines[0])==VCF_REF ) + { + // By default, REF lines are merged with SNPs if SNPs and indels are to be kept separately. + // However, if there are indels only and a single REF line, merge it with indels. + args->nblines++; + int i,m = args->mblines; + hts_expand(bcf1_t*,args->nblines,args->mblines,args->blines); + for (i=m; imblines; i++) args->blines[i] = bcf_init1(); + SWAP(bcf1_t*, args->blines[args->nblines-1], args->alines[0]); + args->nalines--; + } + if ( args->nalines ) + { + if ( args->nalines==1 ) + { + args->nalines = 0; + return args->alines[0]; + } + bcf_clear(args->mrow_out); + merge_biallelics_to_multiallelic(args, args->mrow_out, args->alines, args->nalines); + args->nalines = 0; + return args->mrow_out; + } + else if ( args->nblines ) + { + if ( args->nblines==1 ) + { + args->nblines = 0; + return args->blines[0]; + } + bcf_clear(args->mrow_out); + merge_biallelics_to_multiallelic(args, args->mrow_out, args->blines, args->nblines); + args->nblines = 0; + return args->mrow_out; + } + return NULL; +} +static void flush_buffer(args_t *args, htsFile *file, int n) +{ + bcf1_t *line; + int i, k; + for (i=0; irbuf); + if ( args->mrows_op==MROWS_MERGE ) + { + if ( mrows_ready_to_flush(args, args->lines[k]) ) + { + while ( (line=mrows_flush(args)) ) bcf_write1(file, args->hdr, line); + } + int merge = 1; + if ( args->mrows_collapse!=COLLAPSE_BOTH && args->mrows_collapse!=COLLAPSE_ANY ) + { + if ( !(bcf_get_variant_types(args->lines[k]) & args->mrows_collapse) ) merge = 0; + } + if ( merge ) + { + mrows_schedule(args, &args->lines[k]); + continue; + } + } + bcf_write1(file, args->hdr, args->lines[k]); + } + if ( args->mrows_op==MROWS_MERGE && !args->rbuf.n ) + { + while ( (line=mrows_flush(args)) ) bcf_write1(file, args->hdr, line); + } +} + +static void init_data(args_t *args) +{ + args->hdr = args->files->readers[0].header; + rbuf_init(&args->rbuf, 100); + args->lines = (bcf1_t**) calloc(args->rbuf.m, sizeof(bcf1_t*)); + if ( args->ref_fname ) + { + args->fai = fai_load(args->ref_fname); + if ( !args->fai ) error("Failed to load the fai index: %s\n", args->ref_fname); + } + if ( args->mrows_op==MROWS_MERGE ) + { + args->mrow_out = bcf_init1(); + args->tmp_str = (kstring_t*) calloc(bcf_hdr_nsamples(args->hdr),sizeof(kstring_t)); + args->diploid = (uint8_t*) malloc(bcf_hdr_nsamples(args->hdr)); + } +} + +static void destroy_data(args_t *args) +{ + int i; + for (i=0; irbuf.m; i++) + if ( args->lines[i] ) bcf_destroy1(args->lines[i]); + free(args->lines); + for (i=0; imtmp_lines; i++) + if ( args->tmp_lines[i] ) bcf_destroy1(args->tmp_lines[i]); + free(args->tmp_lines); + for (i=0; imalines; i++) + bcf_destroy1(args->alines[i]); + free(args->alines); + for (i=0; imblines; i++) + bcf_destroy1(args->blines[i]); + free(args->blines); + for (i=0; immaps; i++) + free(args->maps[i].map); + for (i=0; intmp_als; i++) + free(args->tmp_als[i].s); + free(args->tmp_als); + free(args->tmp_als_str.s); + if ( args->tmp_str ) + { + for (i=0; ihdr); i++) free(args->tmp_str[i].s); + free(args->tmp_str); + } + free(args->maps); + free(args->als); + free(args->tmp_arr1); + free(args->tmp_arr2); + free(args->diploid); + if ( args->mrow_out ) bcf_destroy1(args->mrow_out); + if ( args->fai ) fai_destroy(args->fai); + if ( args->mseq ) free(args->seq); +} + + +static void normalize_line(args_t *args, bcf1_t **line_ptr) +{ + bcf1_t *line = *line_ptr; + if ( args->fai ) + { + if ( args->check_ref & CHECK_REF_FIX ) fix_ref(args, line); + if ( args->do_indels ) + { + int ret = realign(args, line); + + // exclude broken VCF lines + if ( ret==ERR_REF_MISMATCH && args->check_ref & CHECK_REF_SKIP ) + { + args->nskipped++; + return; + } + if ( ret==ERR_DUP_ALLELE ) + { + if ( args->check_ref & CHECK_REF_FIX ) + fix_dup_alt(args, line); + else if ( args->check_ref==CHECK_REF_EXIT ) + error("Duplicate alleles at %s:%d; run with -cw to turn the error into warning or with -cs to fix.\n", bcf_seqname(args->hdr,line),line->pos+1); + else if ( args->check_ref & CHECK_REF_WARN ) + fprintf(stderr,"ALT_DUP\t%s\t%d\n", bcf_seqname(args->hdr,line),line->pos+1); + } + } + } + + // insert into sorted buffer + rbuf_expand0(&args->rbuf,bcf1_t*,args->rbuf.n+1,args->lines); + int i,j; + i = j = rbuf_append(&args->rbuf); + if ( !args->lines[i] ) args->lines[i] = bcf_init1(); + SWAP(bcf1_t*, (*line_ptr), args->lines[i]); + while ( rbuf_prev(&args->rbuf,&i) ) + { + if ( args->lines[i]->pos > args->lines[j]->pos ) SWAP(bcf1_t*, args->lines[i], args->lines[j]); + j = i; + } +} + +static void normalize_vcf(args_t *args) +{ + htsFile *out = hts_open(args->output_fname, hts_bcf_wmode(args->output_type)); + if ( out == NULL ) error("Can't write to \"%s\": %s\n", args->output_fname, strerror(errno)); + if ( args->n_threads ) + hts_set_opt(out, HTS_OPT_THREAD_POOL, args->files->p); + if (args->record_cmd_line) bcf_hdr_append_version(args->hdr, args->argc, args->argv, "bcftools_norm"); + bcf_hdr_write(out, args->hdr); + + int prev_rid = -1, prev_pos = -1, prev_type = 0; + while ( bcf_sr_next_line(args->files) ) + { + args->ntotal++; + + bcf1_t *line = args->files->readers[0].buffer[0]; + if ( args->rmdup ) + { + int line_type = bcf_get_variant_types(line); + if ( prev_rid>=0 && prev_rid==line->rid && prev_pos==line->pos ) + { + if ( (args->rmdup>>1)&COLLAPSE_ANY ) continue; + if ( (args->rmdup>>1)&COLLAPSE_SNPS && line_type&(VCF_SNP|VCF_MNP) && prev_type&(VCF_SNP|VCF_MNP) ) continue; + if ( (args->rmdup>>1)&COLLAPSE_INDELS && line_type&(VCF_INDEL) && prev_type&(VCF_INDEL) ) continue; + } + else + { + prev_rid = line->rid; + prev_pos = line->pos; + prev_type = 0; + } + prev_type |= line_type; + } + + // still on the same chromosome? + int i,j,ilast = rbuf_last(&args->rbuf); + if ( ilast>=0 && line->rid != args->lines[ilast]->rid ) flush_buffer(args, out, args->rbuf.n); // new chromosome + + int split = 0; + if ( args->mrows_op==MROWS_SPLIT ) + { + split = 1; + if ( args->mrows_collapse!=COLLAPSE_BOTH && args->mrows_collapse!=COLLAPSE_ANY ) + { + if ( !(bcf_get_variant_types(line) & args->mrows_collapse) ) split = 0; + } + if ( split && line->n_allele>2 ) + { + args->nsplit++; + split_multiallelic_to_biallelics(args, line); + for (j=0; jntmp_lines; j++) + normalize_line(args, &args->tmp_lines[j]); + } + else + split = 0; + } + if ( !split ) + normalize_line(args, &args->files->readers[0].buffer[0]); + + // find out how many sites to flush + ilast = rbuf_last(&args->rbuf); + j = 0; + for (i=-1; rbuf_next(&args->rbuf,&i); ) + { + if ( args->lines[ilast]->pos - args->lines[i]->pos < args->buf_win ) break; + j++; + } + if ( j>0 ) flush_buffer(args, out, j); + } + flush_buffer(args, out, args->rbuf.n); + hts_close(out); + + fprintf(stderr,"Lines total/split/realigned/skipped:\t%d/%d/%d/%d\n", args->ntotal,args->nsplit,args->nchanged,args->nskipped); + if ( args->check_ref & CHECK_REF_FIX ) + fprintf(stderr,"REF/ALT total/modified/added: \t%d/%d/%d\n", args->nref.tot,args->nref.swap,args->nref.set); +} + +static void usage(void) +{ + fprintf(stderr, "\n"); + fprintf(stderr, "About: Left-align and normalize indels; check if REF alleles match the reference;\n"); + fprintf(stderr, " split multiallelic sites into multiple rows; recover multiallelics from\n"); + fprintf(stderr, " multiple rows.\n"); + fprintf(stderr, "Usage: bcftools norm [options] \n"); + fprintf(stderr, "\n"); + fprintf(stderr, "Options:\n"); + fprintf(stderr, " -c, --check-ref check REF alleles and exit (e), warn (w), exclude (x), or set (s) bad sites [e]\n"); + fprintf(stderr, " -D, --remove-duplicates remove duplicate lines of the same type.\n"); + fprintf(stderr, " -d, --rm-dup remove duplicate snps|indels|both|any\n"); + fprintf(stderr, " -f, --fasta-ref reference sequence (MANDATORY)\n"); + fprintf(stderr, " -m, --multiallelics <-|+>[type] split multiallelics (-) or join biallelics (+), type: snps|indels|both|any [both]\n"); + fprintf(stderr, " --no-version do not append version and command line to the header\n"); + fprintf(stderr, " -N, --do-not-normalize do not normalize indels (with -m or -c s)\n"); + fprintf(stderr, " -o, --output write output to a file [standard output]\n"); + fprintf(stderr, " -O, --output-type 'b' compressed BCF; 'u' uncompressed BCF; 'z' compressed VCF; 'v' uncompressed VCF [v]\n"); + fprintf(stderr, " -r, --regions restrict to comma-separated list of regions\n"); + fprintf(stderr, " -R, --regions-file restrict to regions listed in a file\n"); + fprintf(stderr, " -s, --strict-filter when merging (-m+), merged site is PASS only if all sites being merged PASS\n"); + fprintf(stderr, " -t, --targets similar to -r but streams rather than index-jumps\n"); + fprintf(stderr, " -T, --targets-file similar to -R but streams rather than index-jumps\n"); + fprintf(stderr, " --threads number of extra (de)compression threads [0]\n"); + fprintf(stderr, " -w, --site-win buffer for sorting lines which changed position during realignment [1000]\n"); + fprintf(stderr, "\n"); + exit(1); +} + +int main_vcfnorm(int argc, char *argv[]) +{ + int c; + args_t *args = (args_t*) calloc(1,sizeof(args_t)); + args->argc = argc; args->argv = argv; + args->files = bcf_sr_init(); + args->output_fname = "-"; + args->output_type = FT_VCF; + args->n_threads = 0; + args->record_cmd_line = 1; + args->aln_win = 100; + args->buf_win = 1000; + args->mrows_collapse = COLLAPSE_BOTH; + args->do_indels = 1; + int region_is_file = 0; + int targets_is_file = 0; + + static struct option loptions[] = + { + {"help",no_argument,NULL,'h'}, + {"fasta-ref",required_argument,NULL,'f'}, + {"do-not-normalize",no_argument,NULL,'N'}, + {"multiallelics",required_argument,NULL,'m'}, + {"regions",required_argument,NULL,'r'}, + {"regions-file",required_argument,NULL,'R'}, + {"targets",required_argument,NULL,'t'}, + {"targets-file",required_argument,NULL,'T'}, + {"site-win",required_argument,NULL,'w'}, + {"remove-duplicates",no_argument,NULL,'D'}, + {"rm-dup",required_argument,NULL,'d'}, + {"output",required_argument,NULL,'o'}, + {"output-type",required_argument,NULL,'O'}, + {"threads",required_argument,NULL,9}, + {"check-ref",required_argument,NULL,'c'}, + {"strict-filter",no_argument,NULL,'s'}, + {"no-version",no_argument,NULL,8}, + {NULL,0,NULL,0} + }; + char *tmp; + while ((c = getopt_long(argc, argv, "hr:R:f:w:Dd:o:O:c:m:t:T:sN",loptions,NULL)) >= 0) { + switch (c) { + case 'N': args->do_indels = 0; break; + case 'd': + if ( !strcmp("snps",optarg) ) args->rmdup = COLLAPSE_SNPS<<1; + else if ( !strcmp("indels",optarg) ) args->rmdup = COLLAPSE_INDELS<<1; + else if ( !strcmp("both",optarg) ) args->rmdup = COLLAPSE_BOTH<<1; + else if ( !strcmp("any",optarg) ) args->rmdup = COLLAPSE_ANY<<1; + else error("The argument to -d not recognised: %s\n", optarg); + break; + case 'm': + if ( optarg[0]=='-' ) args->mrows_op = MROWS_SPLIT; + else if ( optarg[0]=='+' ) args->mrows_op = MROWS_MERGE; + else error("Expected '+' or '-' with -m\n"); + if ( optarg[1]!=0 ) + { + if ( !strcmp("snps",optarg+1) ) args->mrows_collapse = COLLAPSE_SNPS; + else if ( !strcmp("indels",optarg+1) ) args->mrows_collapse = COLLAPSE_INDELS; + else if ( !strcmp("both",optarg+1) ) args->mrows_collapse = COLLAPSE_BOTH; + else if ( !strcmp("any",optarg+1) ) args->mrows_collapse = COLLAPSE_ANY; + else error("The argument to -m not recognised: %s\n", optarg); + } + break; + case 'c': + if ( strchr(optarg,'w') ) args->check_ref |= CHECK_REF_WARN; + if ( strchr(optarg,'x') ) args->check_ref |= CHECK_REF_SKIP; + if ( strchr(optarg,'s') ) args->check_ref |= CHECK_REF_FIX; + if ( strchr(optarg,'e') ) args->check_ref = CHECK_REF_EXIT; // overrides the above + break; + case 'O': + switch (optarg[0]) { + case 'b': args->output_type = FT_BCF_GZ; break; + case 'u': args->output_type = FT_BCF; break; + case 'z': args->output_type = FT_VCF_GZ; break; + case 'v': args->output_type = FT_VCF; break; + default: error("The output type \"%s\" not recognised\n", optarg); + } + break; + case 'o': args->output_fname = optarg; break; + case 'D': + fprintf(stderr,"Warning: `-D` is functional but deprecated, replaced by `-d both`.\n"); + args->rmdup = COLLAPSE_NONE<<1; + break; + case 's': args->strict_filter = 1; break; + case 'f': args->ref_fname = optarg; break; + case 'r': args->region = optarg; break; + case 'R': args->region = optarg; region_is_file = 1; break; + case 't': args->targets = optarg; break; + case 'T': args->targets = optarg; targets_is_file = 1; break; + case 'w': + args->buf_win = strtol(optarg,&tmp,10); + if ( *tmp ) error("Could not parse argument: --site-win %s\n", optarg); + break; + case 9 : args->n_threads = strtol(optarg, 0, 0); break; + case 8 : args->record_cmd_line = 0; break; + case 'h': + case '?': usage(); + default: error("Unknown argument: %s\n", optarg); + } + } + if ( argc>optind+1 ) usage(); + if ( !args->ref_fname && !args->mrows_op && !args->rmdup ) usage(); + if ( !args->ref_fname && args->check_ref&CHECK_REF_FIX ) error("Expected --fasta-ref with --check-ref s\n"); + char *fname = NULL; + if ( optind>=argc ) + { + if ( !isatty(fileno((FILE *)stdin)) ) fname = "-"; // reading from stdin + else usage(); + } + else fname = argv[optind]; + + if ( args->region ) + { + if ( bcf_sr_set_regions(args->files, args->region,region_is_file)<0 ) + error("Failed to read the regions: %s\n", args->region); + } + if ( args->targets ) + { + if ( bcf_sr_set_targets(args->files, args->targets,targets_is_file, 0)<0 ) + error("Failed to read the targets: %s\n", args->targets); + } + + if ( bcf_sr_set_threads(args->files, args->n_threads)<0 ) error("Failed to create threads\n"); + if ( !bcf_sr_add_reader(args->files, fname) ) error("Failed to open %s: %s\n", fname,bcf_sr_strerror(args->files->errnum)); + if ( args->mrows_op&MROWS_SPLIT && args->rmdup ) error("Cannot combine -D and -m-\n"); + init_data(args); + normalize_vcf(args); + destroy_data(args); + bcf_sr_destroy(args->files); + free(args); + return 0; +} + diff --git a/vcfplugin.c b/vcfplugin.c new file mode 100644 index 0000000..bfd6ad2 --- /dev/null +++ b/vcfplugin.c @@ -0,0 +1,643 @@ +/* vcfplugin.c -- plugin modules for operating on VCF/BCF files. + + Copyright (C) 2013-2016 Genome Research Ltd. + + Author: Petr Danecek + +Permission is hereby granted, free of charge, to any person obtaining a copy +of this software and associated documentation files (the "Software"), to deal +in the Software without restriction, including without limitation the rights +to use, copy, modify, merge, publish, distribute, sublicense, and/or sell +copies of the Software, and to permit persons to whom the Software is +furnished to do so, subject to the following conditions: + +The above copyright notice and this permission notice shall be included in +all copies or substantial portions of the Software. + +THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE +AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER +LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, +OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN +THE SOFTWARE. */ + +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include "bcftools.h" +#include "vcmp.h" +#include "filter.h" + +typedef struct _plugin_t plugin_t; + +/** + * Plugin API: + * ---------- + * const char *about(void) + * - short description used by 'bcftools plugin -lv' + * + * const char *usage(void) + * - longer description used by 'bcftools +name -h' + * + * int run(int argc, char **argv) + * - if implemented, the control is immediately handed over to the plugin, + * none of the init/process/destroy functions is called. Return 0 on + * success or non-zero value on error. + * + * int init(int argc, char **argv, bcf_hdr_t *in_hdr, bcf_hdr_t *out_hdr) + * - called once at startup, allows to initialize local variables. + * Return 1 to suppress normal VCF/BCF header output, -1 on critical + * errors, 0 otherwise. + * + * bcf1_t *process(bcf1_t *rec) + * - called for each VCF record, return NULL for no output + * + * void destroy(void) + * - called after all lines have been processed to clean up + */ +typedef void (*dl_version_f) (const char **, const char **); +typedef int (*dl_run_f) (int, char **); +typedef int (*dl_init_f) (int, char **, bcf_hdr_t *, bcf_hdr_t *); +typedef char* (*dl_about_f) (void); +typedef char* (*dl_usage_f) (void); +typedef bcf1_t* (*dl_process_f) (bcf1_t *); +typedef void (*dl_destroy_f) (void); + +struct _plugin_t +{ + int argc; + char *name, **argv; + dl_version_f version; + dl_run_f run; + dl_init_f init; + dl_about_f about; + dl_usage_f usage; + dl_process_f process; + dl_destroy_f destroy; + void *handle; +}; + + +struct _args_t; + +typedef struct _rm_tag_t +{ + char *key; + int hdr_id; + void (*handler)(struct _args_t *, bcf1_t *, struct _rm_tag_t *); +} +rm_tag_t; + +typedef struct +{ + char **cols; + int ncols, mcols; + char **als; + int nals, mals; + kstring_t line; + int rid, start, end; +} +annot_line_t; + +typedef struct _annot_col_t +{ + int icol, replace; + char *hdr_key; + int (*setter)(struct _args_t *, bcf1_t *, struct _annot_col_t *, void*); +} +annot_col_t; + +// Logic of the filters: include or exclude sites which match the filters? +#define FLT_INCLUDE 1 +#define FLT_EXCLUDE 2 + +typedef struct _args_t +{ + bcf_srs_t *files; + bcf_hdr_t *hdr, *hdr_out; + htsFile *out_fh; + int output_type, n_threads; + + filter_t *filter; + char *filter_str; + int filter_logic; // include or exclude sites which match the filters? One of FLT_INCLUDE/FLT_EXCLUDE + + plugin_t plugin; + int nplugin_paths; + char **plugin_paths; + + char **argv, *output_fname, *regions_list, *targets_list; + int argc, drop_header, verbose, record_cmd_line; +} +args_t; + +char *msprintf(const char *fmt, ...); + +static void add_plugin_paths(args_t *args, const char *path) +{ + while (1) + { + size_t len = strcspn(path, ":"); + + if ( len == 0 ) + { +#ifdef PLUGINPATH + add_plugin_paths(args, PLUGINPATH); +#endif + } + else + { + char *dir = (char *) malloc(len + 1); + strncpy(dir, path, len); + dir[len] = '\0'; + + struct stat st; + if ( stat(dir, &st) == 0 ) + { + args->plugin_paths = (char**) realloc(args->plugin_paths,sizeof(char*)*(args->nplugin_paths+1)); + args->plugin_paths[args->nplugin_paths] = dir; + args->nplugin_paths++; + if ( args->verbose > 1 ) fprintf(stderr, "plugin directory %s .. ok\n", dir); + } + else + { + if ( args->verbose > 1 ) fprintf(stderr, "plugin directory %s .. %s\n", dir, strerror(errno)); + free(dir); + } + + } + + path += len; + if ( *path == ':' ) path++; + else break; + } +} + +static void init_plugin_paths(args_t *args) +{ + if ( args->nplugin_paths!=-1 ) return; + + args->nplugin_paths = 0; + args->plugin_paths = NULL; + + char *path = getenv("BCFTOOLS_PLUGINS"); + add_plugin_paths(args, path ? path : ""); +} + +static void *dlopen_plugin(args_t *args, const char *fname) +{ + init_plugin_paths(args); + + void *handle; + char *tmp; + if ( fname[0]!='/' ) // not an absolute path + { + int i; + for (i=0; inplugin_paths; i++) + { + tmp = msprintf("%s/%s.so", args->plugin_paths[i],fname); + handle = dlopen(tmp, RTLD_NOW); // valgrind complains about unfreed memory, not our problem though + if ( args->verbose > 1 ) + { + if ( !handle ) fprintf(stderr,"%s:\n\tdlopen .. %s\n", tmp,dlerror()); + else fprintf(stderr,"%s:\n\tdlopen .. ok\n", tmp); + } + free(tmp); + if ( handle ) return handle; + } + } + + handle = dlopen(fname, RTLD_NOW); + if ( args->verbose > 1 ) + { + if ( !handle ) fprintf(stderr,"%s:\n\tdlopen .. %s\n", fname,dlerror()); + else fprintf(stderr,"%s:\n\tdlopen .. ok\n", fname); + } + + return handle; +} + +static void print_plugin_usage_hint(void) +{ + fprintf(stderr, "\nNo functional bcftools plugins were found"); + if ( !getenv("BCFTOOLS_PLUGINS") ) + fprintf(stderr,". The environment variable BCFTOOLS_PLUGINS is not set.\n\n"); + else + fprintf(stderr, + " in\n\tBCFTOOLS_PLUGINS=\"%s\".\n\n" + "- Is the plugin path correct?\n\n" + "- Run \"bcftools plugin -lv\" for more detailed error output.\n" + "\n", + getenv("BCFTOOLS_PLUGINS") + ); +} + +static int load_plugin(args_t *args, const char *fname, int exit_on_error, plugin_t *plugin) +{ + plugin->name = strdup(fname); + + plugin->handle = dlopen_plugin(args, fname); + if ( !plugin->handle ) + { + if ( exit_on_error ) + { + print_plugin_usage_hint(); + error("Could not load \"%s\".\n\n", fname); + } + return -1; + } + + dlerror(); + plugin->init = (dl_init_f) dlsym(plugin->handle, "init"); + char *ret = dlerror(); + if ( ret ) + plugin->init = NULL; + else + if ( args->verbose > 1 ) fprintf(stderr,"\tinit .. ok\n"); + + plugin->run = (dl_run_f) dlsym(plugin->handle, "run"); + ret = dlerror(); + if ( ret ) + plugin->run = NULL; + else + if ( args->verbose > 1 ) fprintf(stderr,"\trun .. ok\n"); + + if ( !plugin->init && !plugin->run ) + { + if ( exit_on_error ) error("Could not initialize %s, neither run or init found \n", plugin->name); + else if ( args->verbose > 1 ) fprintf(stderr,"\tinit/run .. not found\n"); + return -1; + } + + plugin->version = (dl_version_f) dlsym(plugin->handle, "version"); + ret = dlerror(); + if ( ret ) + { + if ( exit_on_error ) error("Could not initialize %s, version string not found\n", plugin->name); + else if ( args->verbose > 1 ) fprintf(stderr,"\tversion .. not found\n"); + return -1; + } + + plugin->about = (dl_about_f) dlsym(plugin->handle, "about"); + ret = dlerror(); + if ( ret ) + { + if ( exit_on_error ) error("Could not initialize %s: %s\n", plugin->name, ret); + return -1; + } + + plugin->usage = (dl_about_f) dlsym(plugin->handle, "usage"); + ret = dlerror(); + if ( ret ) + plugin->usage = plugin->about; + + if ( plugin->run ) return 0; + + plugin->process = (dl_process_f) dlsym(plugin->handle, "process"); + ret = dlerror(); + if ( ret ) + { + if ( exit_on_error ) error("Could not initialize %s: %s\n", plugin->name, ret); + return -1; + } + + plugin->destroy = (dl_destroy_f) dlsym(plugin->handle, "destroy"); + ret = dlerror(); + if ( ret ) + { + if ( exit_on_error ) error("Could not initialize %s: %s\n", plugin->name, ret); + return -1; + } + + return 0; +} + +static void init_plugin(args_t *args) +{ + static int warned_bcftools = 0, warned_htslib = 0; + + int ret = args->plugin.init(args->plugin.argc,args->plugin.argv,args->hdr,args->hdr_out); + if ( ret<0 ) error("The plugin exited with an error.\n"); + const char *bver, *hver; + args->plugin.version(&bver, &hver); + if ( strcmp(bver,bcftools_version()) && !warned_bcftools ) + { + fprintf(stderr,"WARNING: bcftools version mismatch .. bcftools at %s, the plugin \"%s\" at %s\n", bcftools_version(),args->plugin.name,bver); + warned_bcftools = 1; + } + if ( strcmp(hver,hts_version()) && !warned_htslib ) + { + fprintf(stderr,"WARNING: htslib version mismatch .. bcftools at %s, the plugin \"%s\" at %s\n", hts_version(),args->plugin.name,hver); + warned_htslib = 1; + } + args->drop_header += ret; +} + +static int cmp_plugin_name(const void *p1, const void *p2) +{ + plugin_t *a = (plugin_t*) p1; + plugin_t *b = (plugin_t*) p2; + return strcmp(a->name,b->name); +} + +static int list_plugins(args_t *args) +{ + plugin_t *plugins = NULL; + int nplugins = 0, mplugins = 0; + + init_plugin_paths(args); + + kstring_t str = {0,0,0}; + int i; + for (i=0; inplugin_paths; i++) + { + DIR *dp = opendir(args->plugin_paths[i]); + if ( dp==NULL ) continue; + + struct dirent *ep; + while ( (ep=readdir(dp)) ) + { + int len = strlen(ep->d_name); + if ( strcasecmp(".so",ep->d_name+len-3) ) continue; + str.l = 0; + ksprintf(&str,"%s/%s", args->plugin_paths[i],ep->d_name); + hts_expand(plugin_t, nplugins+1, mplugins, plugins); + if ( load_plugin(args, str.s, 0, &plugins[nplugins]) < 0 ) continue; + nplugins++; + str.l = 0; + kputs(ep->d_name, &str); + int l = str.l - 1; + while ( l>=0 && str.s[l]!='.' ) l--; + if ( l>=0 ) str.s[l] = 0; + free(plugins[nplugins-1].name); + plugins[nplugins-1].name = strdup(str.s); // use a short name + } + closedir(dp); + } + if ( nplugins ) + { + qsort(plugins, nplugins, sizeof(plugins[0]), cmp_plugin_name); + + for (i=0; iverbose ) + printf("\n-- %s --\n%s", plugins[i].name, plugins[i].about()); + else + printf("%s\n", plugins[i].name); + } + if ( args->verbose ) printf("\n"); + } + else + print_plugin_usage_hint(); + free(str.s); + return nplugins ? 0 : 1; +} + +static void init_data(args_t *args) +{ + args->hdr = args->files->readers[0].header; + args->hdr_out = bcf_hdr_dup(args->hdr); + + init_plugin(args); + + if ( args->filter_str ) + args->filter = filter_init(args->hdr, args->filter_str); + + if (args->record_cmd_line) bcf_hdr_append_version(args->hdr_out, args->argc, args->argv, "bcftools_plugin"); + if ( !args->drop_header ) + { + args->out_fh = hts_open(args->output_fname,hts_bcf_wmode(args->output_type)); + if ( args->out_fh == NULL ) error("Can't write to \"%s\": %s\n", args->output_fname, strerror(errno)); + if ( args->n_threads ) hts_set_threads(args->out_fh, args->n_threads); + bcf_hdr_write(args->out_fh, args->hdr_out); + } +} + +static void destroy_data(args_t *args) +{ + free(args->plugin.name); + if ( args->plugin.destroy ) args->plugin.destroy(); + dlclose(args->plugin.handle); + if ( args->hdr_out ) bcf_hdr_destroy(args->hdr_out); + if ( args->nplugin_paths>0 ) + { + int i; + for (i=0; inplugin_paths; i++) free(args->plugin_paths[i]); + free(args->plugin_paths); + } + if ( args->filter ) + filter_destroy(args->filter); + if (args->out_fh) hts_close(args->out_fh); +} + +static void usage(args_t *args) +{ + fprintf(stderr, "\n"); + fprintf(stderr, "About: Run user defined plugin\n"); + fprintf(stderr, "Usage: bcftools plugin [OPTIONS] [-- PLUGIN_OPTIONS]\n"); + fprintf(stderr, " bcftools +name [OPTIONS] [-- PLUGIN_OPTIONS]\n"); + fprintf(stderr, "\n"); + fprintf(stderr, "VCF input options:\n"); + fprintf(stderr, " -e, --exclude exclude sites for which the expression is true\n"); + fprintf(stderr, " -i, --include select sites for which the expression is true\n"); + fprintf(stderr, " -r, --regions restrict to comma-separated list of regions\n"); + fprintf(stderr, " -R, --regions-file restrict to regions listed in a file\n"); + fprintf(stderr, " -t, --targets similar to -r but streams rather than index-jumps\n"); + fprintf(stderr, " -T, --targets-file similar to -R but streams rather than index-jumps\n"); + fprintf(stderr, "VCF output options:\n"); + fprintf(stderr, " --no-version do not append version and command line to the header\n"); + fprintf(stderr, " -o, --output write output to a file [standard output]\n"); + fprintf(stderr, " -O, --output-type 'b' compressed BCF; 'u' uncompressed BCF; 'z' compressed VCF; 'v' uncompressed VCF [v]\n"); + fprintf(stderr, " --threads number of extra output compression threads [0]\n"); + fprintf(stderr, "Plugin options:\n"); + fprintf(stderr, " -h, --help list plugin's options\n"); + fprintf(stderr, " -l, --list-plugins list available plugins. See BCFTOOLS_PLUGINS environment variable and man page for details\n"); + fprintf(stderr, " -v, --verbose print verbose information, -vv increases verbosity\n"); + fprintf(stderr, " -V, --version print version string and exit\n"); + fprintf(stderr, "\n"); + exit(1); +} + +static int is_verbose(int argc, char *argv[]) +{ + int c, verbose = 0, opterr_ori = opterr; + static struct option loptions[] = + { + {"verbose",no_argument,NULL,'v'}, + {NULL,0,NULL,0} + }; + opterr = 0; + while ((c = getopt_long(argc, argv, "-v",loptions,NULL)) >= 0) + { + switch (c) { + case 'v': verbose++; break; + case 1: + default: break; + } + } + opterr = opterr_ori; + optind = 0; + return verbose; +} +int main_plugin(int argc, char *argv[]) +{ + int c; + args_t *args = (args_t*) calloc(1,sizeof(args_t)); + args->argc = argc; args->argv = argv; + args->output_fname = "-"; + args->output_type = FT_VCF; + args->n_threads = 0; + args->record_cmd_line = 1; + args->nplugin_paths = -1; + int regions_is_file = 0, targets_is_file = 0, plist_only = 0, usage_only = 0, version_only = 0; + + if ( argc==1 ) usage(args); + + char *plugin_name = NULL; + if ( argv[1][0]!='-' ) + { + args->verbose = is_verbose(argc, argv); + plugin_name = argv[1]; + argc--; + argv++; + load_plugin(args, plugin_name, 1, &args->plugin); + if ( args->plugin.run ) + { + int ret = args->plugin.run(argc, argv); + destroy_data(args); + free(args); + return ret; + } + } + + static struct option loptions[] = + { + {"version",no_argument,NULL,'V'}, + {"verbose",no_argument,NULL,'v'}, + {"help",no_argument,NULL,'h'}, + {"list-plugins",no_argument,NULL,'l'}, + {"output",required_argument,NULL,'o'}, + {"output-type",required_argument,NULL,'O'}, + {"threads",required_argument,NULL,9}, + {"include",required_argument,NULL,'i'}, + {"exclude",required_argument,NULL,'e'}, + {"regions",required_argument,NULL,'r'}, + {"regions-file",required_argument,NULL,'R'}, + {"targets",required_argument,NULL,'t'}, + {"targets-file",required_argument,NULL,'T'}, + {"no-version",no_argument,NULL,8}, + {NULL,0,NULL,0} + }; + while ((c = getopt_long(argc, argv, "h?o:O:r:R:t:T:li:e:vV",loptions,NULL)) >= 0) + { + switch (c) { + case 'V': version_only = 1; break; + case 'v': args->verbose++; break; + case 'o': args->output_fname = optarg; break; + case 'O': + switch (optarg[0]) { + case 'b': args->output_type = FT_BCF_GZ; break; + case 'u': args->output_type = FT_BCF; break; + case 'z': args->output_type = FT_VCF_GZ; break; + case 'v': args->output_type = FT_VCF; break; + default: error("The output type \"%s\" not recognised\n", optarg); + }; + break; + case 'e': args->filter_str = optarg; args->filter_logic |= FLT_EXCLUDE; break; + case 'i': args->filter_str = optarg; args->filter_logic |= FLT_INCLUDE; break; + case 'r': args->regions_list = optarg; break; + case 'R': args->regions_list = optarg; regions_is_file = 1; break; + case 't': args->targets_list = optarg; break; + case 'T': args->targets_list = optarg; targets_is_file = 1; break; + case 'l': plist_only = 1; break; + case 9 : args->n_threads = strtol(optarg, 0, 0); break; + case 8 : args->record_cmd_line = 0; break; + case '?': + case 'h': usage_only = 1; break; + default: error("Unknown argument: %s\n", optarg); + } + } + if ( plist_only ) return list_plugins(args); + if ( usage_only && ! plugin_name ) usage(args); + + if ( version_only ) + { + const char *bver, *hver; + args->plugin.version(&bver, &hver); + printf("bcftools %s using htslib %s\n", bcftools_version(), hts_version()); + printf("plugin at %s using htslib %s\n\n", bver, hver); + return 0; + } + + if ( usage_only ) + { + if ( args->plugin.usage ) + fprintf(stderr,"%s",args->plugin.usage()); + else + fprintf(stderr,"Usage: bcftools +%s [General Options] -- [Plugin Options]\n",plugin_name); + return 0; + } + + char *fname = NULL; + if ( optind>=argc || argv[optind][0]=='-' ) + { + if ( !isatty(fileno((FILE *)stdin)) ) fname = "-"; // reading from stdin + else usage(args); + args->plugin.argc = argc - optind + 1; + args->plugin.argv = argv + optind - 1; + } + else + { + fname = argv[optind]; + args->plugin.argc = argc - optind; + args->plugin.argv = argv + optind; + } + optind = 0; + + args->files = bcf_sr_init(); + if ( args->regions_list ) + { + if ( bcf_sr_set_regions(args->files, args->regions_list, regions_is_file)<0 ) + error("Failed to read the regions: %s\n", args->regions_list); + } + if ( args->targets_list ) + { + if ( bcf_sr_set_targets(args->files, args->targets_list, targets_is_file, 0)<0 ) + error("Failed to read the targets: %s\n", args->targets_list); + args->files->collapse |= COLLAPSE_SOME; + } + if ( !bcf_sr_add_reader(args->files, fname) ) error("Failed to open %s: %s\n", fname,bcf_sr_strerror(args->files->errnum)); + + init_data(args); + while ( bcf_sr_next_line(args->files) ) + { + bcf1_t *line = bcf_sr_get_line(args->files,0); + if ( args->filter ) + { + int pass = filter_test(args->filter, line, NULL); + if ( args->filter_logic & FLT_EXCLUDE ) pass = pass ? 0 : 1; + if ( !pass ) continue; + } + line = args->plugin.process(line); + if ( line ) bcf_write1(args->out_fh, args->hdr_out, line); + } + destroy_data(args); + bcf_sr_destroy(args->files); + free(args); + return 0; +} + diff --git a/vcfquery.c b/vcfquery.c new file mode 100644 index 0000000..ab4c100 --- /dev/null +++ b/vcfquery.c @@ -0,0 +1,373 @@ +/* vcfquery.c -- Extracts fields from VCF/BCF file. + + Copyright (C) 2013-2014 Genome Research Ltd. + + Author: Petr Danecek + +Permission is hereby granted, free of charge, to any person obtaining a copy +of this software and associated documentation files (the "Software"), to deal +in the Software without restriction, including without limitation the rights +to use, copy, modify, merge, publish, distribute, sublicense, and/or sell +copies of the Software, and to permit persons to whom the Software is +furnished to do so, subject to the following conditions: + +The above copyright notice and this permission notice shall be included in +all copies or substantial portions of the Software. + +THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE +AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER +LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, +OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN +THE SOFTWARE. */ + +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include "bcftools.h" +#include "filter.h" +#include "convert.h" + + +// Logic of the filters: include or exclude sites which match the filters? +#define FLT_INCLUDE 1 +#define FLT_EXCLUDE 2 + +typedef struct +{ + filter_t *filter; + char *filter_str; + int filter_logic; // include or exclude sites which match the filters? One of FLT_INCLUDE/FLT_EXCLUDE + convert_t *convert; + bcf_srs_t *files; + bcf_hdr_t *header; + int nsamples, *samples, sample_is_file; + char **argv, *format_str, *sample_list, *targets_list, *regions_list, *vcf_list, *fn_out; + int argc, list_columns, print_header, allow_undef_tags; + FILE *out; +} +args_t; + +static void destroy_list(char **list, int n) +{ + int i; + for (i=0; iheader = args->files->readers[0].header; + + int i, nsamples = 0, *samples = NULL; + if ( args->sample_list && strcmp("-",args->sample_list) ) + { + for (i=0; ifiles->nreaders; i++) + { + int ret = bcf_hdr_set_samples(args->files->readers[i].header,args->sample_list,args->sample_is_file); + if ( ret<0 ) error("Error parsing the sample list\n"); + else if ( ret>0 ) error("Sample name mismatch: sample #%d not found in the header\n", ret); + } + + if ( args->sample_list[0]!='^' ) + { + // the sample ordering may be different if not negated + int n; + char **smpls = hts_readlist(args->sample_list, args->sample_is_file, &n); + if ( !smpls ) error("Could not parse %s\n", args->sample_list); + if ( n!=bcf_hdr_nsamples(args->files->readers[0].header) ) + error("The number of samples does not match, perhaps some are present multiple times?\n"); + nsamples = bcf_hdr_nsamples(args->files->readers[0].header); + samples = (int*) malloc(sizeof(int)*nsamples); + for (i=0; ifiles->readers[0].header, BCF_DT_SAMPLE,smpls[i]); + free(smpls[i]); + } + free(smpls); + } + } + args->convert = convert_init(args->header, samples, nsamples, args->format_str); + if ( args->allow_undef_tags ) convert_set_option(args->convert, allow_undef_tags, 1); + free(samples); + + int max_unpack = convert_max_unpack(args->convert); + if ( args->filter_str ) + { + args->filter = filter_init(args->header, args->filter_str); + max_unpack |= filter_max_unpack(args->filter); + } + args->files->max_unpack = max_unpack; +} + +static void destroy_data(args_t *args) +{ + convert_destroy(args->convert); + if ( args->filter ) + filter_destroy(args->filter); + free(args->samples); +} + +static void query_vcf(args_t *args) +{ + kstring_t str = {0,0,0}; + + if ( args->print_header ) + { + convert_header(args->convert,&str); + fwrite(str.s, str.l, 1, args->out); + } + + while ( bcf_sr_next_line(args->files) ) + { + if ( !bcf_sr_has_line(args->files,0) ) continue; + bcf1_t *line = args->files->readers[0].buffer[0]; + bcf_unpack(line, args->files->max_unpack); + + if ( args->filter ) + { + int pass = filter_test(args->filter, line, NULL); + if ( args->filter_logic & FLT_EXCLUDE ) pass = pass ? 0 : 1; + if ( !pass ) continue; + } + + str.l = 0; + convert_line(args->convert, line, &str); + if ( str.l ) + fwrite(str.s, str.l, 1, args->out); + } + if ( str.m ) free(str.s); +} + +static void list_columns(args_t *args) +{ + int i; + bcf_sr_t *reader = &args->files->readers[0]; + for (i=0; iheader); i++) + printf("%s\n", reader->header->samples[i]); +} + +static char **copy_header(bcf_hdr_t *hdr, char **src, int nsrc) +{ + char **dst = (char**) malloc(sizeof(char*)*nsrc); + int i; + for (i=0; i [ [...]]\n"); + fprintf(stderr, "\n"); + fprintf(stderr, "Options:\n"); + fprintf(stderr, " -c, --collapse collapse lines with duplicate positions for , see man page [none]\n"); + fprintf(stderr, " -e, --exclude exclude sites for which the expression is true (see man page for details)\n"); + fprintf(stderr, " -f, --format see man page for details\n"); + fprintf(stderr, " -H, --print-header print header\n"); + fprintf(stderr, " -i, --include select sites for which the expression is true (see man page for details)\n"); + fprintf(stderr, " -l, --list-samples print the list of samples and exit\n"); + fprintf(stderr, " -o, --output-file output file name [stdout]\n"); + fprintf(stderr, " -r, --regions restrict to comma-separated list of regions\n"); + fprintf(stderr, " -R, --regions-file restrict to regions listed in a file\n"); + fprintf(stderr, " -s, --samples list of samples to include\n"); + fprintf(stderr, " -S, --samples-file file of samples to include\n"); + fprintf(stderr, " -t, --targets similar to -r but streams rather than index-jumps\n"); + fprintf(stderr, " -T, --targets-file similar to -R but streams rather than index-jumps\n"); + fprintf(stderr, " -u, --allow-undef-tags print \".\" for undefined tags\n"); + fprintf(stderr, " -v, --vcf-list process multiple VCFs listed in the file\n"); + fprintf(stderr, "\n"); + fprintf(stderr, "Examples:\n"); + fprintf(stderr, "\tbcftools query -f '%%CHROM\\t%%POS\\t%%REF\\t%%ALT[\\t%%SAMPLE=%%GT]\\n' file.vcf.gz\n"); + fprintf(stderr, "\n"); + exit(1); +} + +int main_vcfquery(int argc, char *argv[]) +{ + int c, collapse = 0; + args_t *args = (args_t*) calloc(1,sizeof(args_t)); + args->argc = argc; args->argv = argv; + int regions_is_file = 0, targets_is_file = 0; + + static struct option loptions[] = + { + {"help",0,0,'h'}, + {"list-samples",0,0,'l'}, + {"include",1,0,'i'}, + {"exclude",1,0,'e'}, + {"format",1,0,'f'}, + {"output-file",1,0,'o'}, + {"regions",1,0,'r'}, + {"regions-file",1,0,'R'}, + {"targets",1,0,'t'}, + {"targets-file",1,0,'T'}, + {"annots",1,0,'a'}, + {"samples",1,0,'s'}, + {"samples-file",1,0,'S'}, + {"print-header",0,0,'H'}, + {"collapse",1,0,'c'}, + {"vcf-list",1,0,'v'}, + {"allow-undef-tags",0,0,'u'}, + {0,0,0,0} + }; + while ((c = getopt_long(argc, argv, "hlr:R:f:a:s:S:Ht:T:c:v:i:e:o:u",loptions,NULL)) >= 0) { + switch (c) { + case 'o': args->fn_out = optarg; break; + case 'f': args->format_str = strdup(optarg); break; + case 'H': args->print_header = 1; break; + case 'v': args->vcf_list = optarg; break; + case 'c': + if ( !strcmp(optarg,"snps") ) collapse |= COLLAPSE_SNPS; + else if ( !strcmp(optarg,"indels") ) collapse |= COLLAPSE_INDELS; + else if ( !strcmp(optarg,"both") ) collapse |= COLLAPSE_SNPS | COLLAPSE_INDELS; + else if ( !strcmp(optarg,"any") ) collapse |= COLLAPSE_ANY; + else if ( !strcmp(optarg,"all") ) collapse |= COLLAPSE_ANY; + else if ( !strcmp(optarg,"some") ) collapse |= COLLAPSE_SOME; + else error("The --collapse string \"%s\" not recognised.\n", optarg); + break; + case 'a': + { + kstring_t str = {0,0,0}; + kputs("%CHROM\t%POS\t%MASK\t%REF\t%ALT\t%", &str); + char *p = optarg; + while ( *p ) + { + if ( *p==',' ) + kputs("\t%", &str); + else + kputc(*p, &str); + p++; + } + kputc('\n', &str); + args->format_str = str.s; + break; + } + case 'e': args->filter_str = optarg; args->filter_logic |= FLT_EXCLUDE; break; + case 'i': args->filter_str = optarg; args->filter_logic |= FLT_INCLUDE; break; + case 'r': args->regions_list = optarg; break; + case 'R': args->regions_list = optarg; regions_is_file = 1; break; + case 't': args->targets_list = optarg; break; + case 'T': args->targets_list = optarg; targets_is_file = 1; break; + case 'l': args->list_columns = 1; break; + case 'u': args->allow_undef_tags = 1; break; + case 's': args->sample_list = optarg; break; + case 'S': args->sample_list = optarg; args->sample_is_file = 1; break; + case 'h': + case '?': usage(); + default: error("Unknown argument: %s\n", optarg); + } + } + + char *fname = NULL; + if ( optind>=argc ) + { + if ( !isatty(fileno((FILE *)stdin)) ) fname = "-"; + } + else fname = argv[optind]; + + if ( args->list_columns ) + { + if ( !fname ) error("Missing the VCF file name\n"); + args->files = bcf_sr_init(); + if ( !bcf_sr_add_reader(args->files, fname) ) error("Failed to open %s: %s\n", fname,bcf_sr_strerror(args->files->errnum)); + list_columns(args); + bcf_sr_destroy(args->files); + free(args); + return 0; + } + + if ( !args->format_str ) usage(); + args->out = args->fn_out ? fopen(args->fn_out, "w") : stdout; + if ( !args->out ) error("%s: %s\n", args->fn_out,strerror(errno)); + + if ( !args->vcf_list ) + { + if ( !fname ) usage(); + args->files = bcf_sr_init(); + args->files->collapse = collapse; + if ( optind+1 < argc ) args->files->require_index = 1; + if ( args->regions_list && bcf_sr_set_regions(args->files, args->regions_list, regions_is_file)<0 ) + error("Failed to read the regions: %s\n", args->regions_list); + if ( args->targets_list ) + { + if ( bcf_sr_set_targets(args->files, args->targets_list, targets_is_file, 0)<0 ) + error("Failed to read the targets: %s\n", args->targets_list); + } + while ( fname ) + { + if ( !bcf_sr_add_reader(args->files, fname) ) error("Failed to open %s: %s\n", fname,bcf_sr_strerror(args->files->errnum)); + fname = ++optind < argc ? argv[optind] : NULL; + } + init_data(args); + query_vcf(args); + free(args->format_str); + destroy_data(args); + bcf_sr_destroy(args->files); + fclose(args->out); + free(args); + return 0; + } + + // multiple VCFs + int i, k, nfiles, prev_nsamples = 0; + char **fnames, **prev_samples = NULL; + fnames = hts_readlist(args->vcf_list, 1, &nfiles); + if ( !nfiles ) error("No files in %s?\n", args->vcf_list); + for (i=0; ifiles = bcf_sr_init(); + args->files->collapse = collapse; + if ( args->regions_list && bcf_sr_set_regions(args->files, args->regions_list, regions_is_file)<0 ) + error("Failed to read the regions: %s\n", args->regions_list); + if ( optind < argc ) args->files->require_index = 1; + if ( args->targets_list ) + { + if ( bcf_sr_set_targets(args->files, args->targets_list,targets_is_file, 0)<0 ) + error("Failed to read the targets: %s\n", args->targets_list); + } + if ( !bcf_sr_add_reader(args->files, fnames[i]) ) error("Failed to open %s: %s\n", fnames[i],bcf_sr_strerror(args->files->errnum)); + for (k=optind; kfiles, argv[k]) ) error("Failed to open %s: %s\n", argv[k],bcf_sr_strerror(args->files->errnum)); + init_data(args); + if ( i==0 ) + prev_samples = copy_header(args->header, args->files->readers[0].header->samples, bcf_hdr_nsamples(args->files->readers[0].header)); + else + { + args->print_header = 0; + if ( compare_header(args->header, args->files->readers[0].header->samples, bcf_hdr_nsamples(args->files->readers[0].header), prev_samples, prev_nsamples) ) + error("Different samples in %s and %s\n", fnames[i-1],fnames[i]); + } + query_vcf(args); + destroy_data(args); + bcf_sr_destroy(args->files); + } + fclose(args->out); + destroy_list(fnames, nfiles); + destroy_list(prev_samples, prev_nsamples); + free(args->format_str); + free(args); + return 0; +} + + diff --git a/vcfroh.c b/vcfroh.c new file mode 100644 index 0000000..9437d7e --- /dev/null +++ b/vcfroh.c @@ -0,0 +1,1220 @@ +/* vcfroh.c -- HMM model for detecting runs of autozygosity. + + Copyright (C) 2013-2015 Genome Research Ltd. + + Author: Petr Danecek + +Permission is hereby granted, free of charge, to any person obtaining a copy +of this software and associated documentation files (the "Software"), to deal +in the Software without restriction, including without limitation the rights +to use, copy, modify, merge, publish, distribute, sublicense, and/or sell +copies of the Software, and to permit persons to whom the Software is +furnished to do so, subject to the following conditions: + +The above copyright notice and this permission notice shall be included in +all copies or substantial portions of the Software. + +THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE +AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER +LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, +OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN +THE SOFTWARE. */ + +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include "bcftools.h" +#include "HMM.h" +#include "smpl_ilist.h" + +#define STATE_HW 0 // normal state, follows Hardy-Weinberg allele frequencies +#define STATE_AZ 1 // autozygous state + +#define OUTPUT_ST (1<<1) +#define OUTPUT_RG (1<<2) +#define OUTPUT_GZ (1<<3) + +/** Genetic map */ +typedef struct +{ + int pos; + double rate; +} +genmap_t; + +/** HMM data for each sample */ +typedef struct +{ + double *eprob; // emission probs [2*nsites,msites] + uint32_t *sites; // positions [nsites,msites] + int nsites, msites; + int igenmap; // current position in genmap + int nused; // some stats to detect if things didn't go wrong + int nrid, *rid, *rid_off; // for viterbi training, keep all chromosomes + void *snapshot; // hmm snapshot + struct { + uint32_t beg,end,nqual; + double qual; + int rid, state; + } rg; +} +smpl_t; + +typedef struct _args_t +{ + bcf_srs_t *files; + bcf_hdr_t *hdr; + double t2AZ, t2HW; // P(AZ|HW) and P(HW|AZ) parameters + double unseen_PL, dflt_AF; + + char *genmap_fname; + genmap_t *genmap; + int ngenmap, mgenmap, igenmap; + double rec_rate; // constant recombination rate if > 0 + + hmm_t *hmm; + double baum_welch_th; + int nrids, *rids, *rid_offs; // multiple chroms with vi_training + int nbuf_max, nbuf_olap; + + float *AFs; + int32_t *itmp; + int mAFs, nitmp, mitmp, pl_hdr_id, gt_hdr_id; + + double pl2p[256], *pdg; + int32_t skip_rid, prev_rid, prev_pos; + + int ntot; // some stats to detect if things didn't go wrong + smpl_t *smpl; // HMM data for each sample + smpl_ilist_t *af_smpl; // list of samples to estimate AF from (--estimate-AF) + smpl_ilist_t *roh_smpl; // list of samples to analyze (--samples, --samples-file) + char *estimate_AF; // list of samples for AF estimate and query sample + int af_from_PL; // estimate AF from FMT/PL rather than FMT/GT + char **argv, *targets_list, *regions_list, *af_fname, *af_tag, *samples, *buffer_size, *output_fname; + int argc, fake_PLs, snps_only, vi_training, samples_is_file, output_type, skip_homref, n_threads; + BGZF *out; + kstring_t str; +} +args_t; + +void set_tprob_genmap(hmm_t *hmm, uint32_t prev_pos, uint32_t pos, void *data, double *tprob); +void set_tprob_rrate(hmm_t *hmm, uint32_t prev_pos, uint32_t pos, void *data, double *tprob); + +void *smalloc(size_t size) +{ + void *mem = malloc(size); + if ( !mem ) error("malloc: Could not allocate %d bytes\n", (int)size); + return mem; +} + +static void init_data(args_t *args) +{ + int i; + + args->prev_rid = args->skip_rid = -1; + args->hdr = args->files->readers[0].header; + + if ( !bcf_hdr_nsamples(args->hdr) ) error("No samples in the VCF?\n"); + + if ( !args->fake_PLs ) + { + args->pl_hdr_id = bcf_hdr_id2int(args->hdr, BCF_DT_ID, "PL"); + if ( !bcf_hdr_idinfo_exists(args->hdr,BCF_HL_FMT,args->pl_hdr_id) ) + error("Error: The FORMAT/PL tag not found in the header, consider running with -G\n"); + if ( bcf_hdr_id2type(args->hdr,BCF_HL_FMT,args->pl_hdr_id)!=BCF_HT_INT ) + error("Error: The FORMAT/PL tag not defined as Integer in the header\n"); + } + + if ( args->estimate_AF ) + { + if ( !strncmp("GT,",args->estimate_AF,3) ) args->estimate_AF += 3; + else if ( !strncmp("PL,",args->estimate_AF,3) ) { args->estimate_AF += 3; args->af_from_PL = 1; } + if ( strcmp("-",args->estimate_AF) ) + args->af_smpl = smpl_ilist_init(args->hdr, args->estimate_AF, 1, SMPL_NONE); + } + + if ( args->estimate_AF || args->fake_PLs ) + { + if ( args->af_from_PL ) + { + args->pl_hdr_id = bcf_hdr_id2int(args->hdr, BCF_DT_ID, "PL"); + if ( !bcf_hdr_idinfo_exists(args->hdr,BCF_HL_FMT,args->pl_hdr_id) ) + error("Error: The FORMAT/PL tag not found in the header\n"); + } + else + { + args->gt_hdr_id = bcf_hdr_id2int(args->hdr, BCF_DT_ID, "GT"); + if ( !bcf_hdr_idinfo_exists(args->hdr,BCF_HL_FMT,args->gt_hdr_id) ) + error("Error: The FORMAT/GT tag not found in the header\n"); + } + } + if ( args->fake_PLs ) + { + args->gt_hdr_id = bcf_hdr_id2int(args->hdr, BCF_DT_ID, "GT"); + if ( !bcf_hdr_idinfo_exists(args->hdr,BCF_HL_FMT,args->gt_hdr_id) ) + error("Error: The FORMAT/GT tag not found in the header\n"); + } + + args->roh_smpl = smpl_ilist_init(args->hdr, args->samples, args->samples_is_file, SMPL_NONE); + if ( args->samples ) + { + // we may be able to subset to a few samples, for a text VCF this can be a major speedup + if ( (bcf_sr_get_reader(args->files,0))->file->format.format==vcf ) + { + kstring_t str = {0,0,0}; + smpl_ilist_t *tmp = args->roh_smpl, *rmme = NULL; + if ( args->af_smpl ) + { + for (i=0; iroh_smpl->n; i++) + { + if ( str.l ) kputc(',', &str); + kputs(args->hdr->samples[args->roh_smpl->idx[i]], &str); + } + for (i=0; iaf_smpl->n; i++) + { + kputc(',', &str); + kputs(args->hdr->samples[args->af_smpl->idx[i]], &str); + } + rmme = tmp = smpl_ilist_init(args->hdr, str.s, 0, SMPL_NONE); + } + if ( tmp->n < bcf_hdr_nsamples(args->hdr) ) + { + str.l = 0; + for (i=0; in; i++) + { + if ( str.l ) kputc(',', &str); + kputs(args->hdr->samples[tmp->idx[i]], &str); + } + int ret = bcf_hdr_set_samples(args->hdr, str.s, 0); + if ( ret<0 ) error("Error parsing the list of samples: %s\n", str.s); + else if ( ret>0 ) error("The %d-th sample not found in the VCF: %s\n", ret,str.s); + + // update sample ids + smpl_ilist_destroy(args->roh_smpl); + args->roh_smpl = smpl_ilist_init(args->hdr, args->samples, args->samples_is_file, SMPL_NONE); + + if ( args->af_smpl ) + { + smpl_ilist_destroy(args->af_smpl); + args->af_smpl = smpl_ilist_init(args->hdr, args->estimate_AF, 1, SMPL_NONE); + } + } + free(str.s); + if ( rmme ) + smpl_ilist_destroy(rmme); + } + } + + // check whether all samples are in this list. If so, the lookup will not be needed + if ( args->af_smpl && args->af_smpl->n == bcf_hdr_nsamples(args->hdr) ) + { + // all samples are in this list + smpl_ilist_destroy(args->af_smpl); + args->af_smpl = NULL; + } + + if ( args->buffer_size ) + { + args->nbuf_olap = -1; + char *end; + double tmp = strtod(args->buffer_size,&end); + if ( *end ) + { + if ( *end!=',') error("Could not parse: --buffer-size %s\n", args->buffer_size); + args->nbuf_olap = strtol(end+1,&end,10); + if ( *end || args->nbuf_olap<0 ) error("Could not parse: --bufer-size %s\n", args->buffer_size); + } + if ( tmp<0 ) + args->nbuf_max = fabs(tmp)*1e6/(4+8*2)/args->roh_smpl->n; + else + args->nbuf_max = tmp; + + if ( args->nbuf_olap<0 ) + args->nbuf_olap = args->nbuf_max*0.01; + } + fprintf(stderr,"Number of target samples: %d\n", args->roh_smpl->n); + fprintf(stderr,"Number of --estimate-AF samples: %d\n", args->af_smpl ? args->af_smpl->n : (args->estimate_AF ? bcf_hdr_nsamples(args->hdr) : 0)); + fprintf(stderr,"Number of sites in the buffer/overlap: "); + if ( args->nbuf_max ) fprintf(stderr,"%d/%d\n", args->nbuf_max,args->nbuf_olap); + else fprintf(stderr,"unlimited\n"); + + args->smpl = (smpl_t*) calloc(args->roh_smpl->n,sizeof(smpl_t)); + + for (i=0; i<256; i++) args->pl2p[i] = pow(10., -i/10.); + + // Init transition matrix and HMM + double tprob[4]; + MAT(tprob,2,STATE_HW,STATE_HW) = 1 - args->t2AZ; + MAT(tprob,2,STATE_HW,STATE_AZ) = args->t2HW; + MAT(tprob,2,STATE_AZ,STATE_HW) = args->t2AZ; + MAT(tprob,2,STATE_AZ,STATE_AZ) = 1 - args->t2HW; + + args->hmm = hmm_init(2, tprob, 10000); + if ( args->genmap_fname ) + hmm_set_tprob_func(args->hmm, set_tprob_genmap, args); + else if ( args->rec_rate > 0 ) + hmm_set_tprob_func(args->hmm, set_tprob_rrate, args); + + args->out = bgzf_open(strcmp("stdout",args->output_fname)?args->output_fname:"-", args->output_type&OUTPUT_GZ ? "wg" : "wu"); + if ( !args->out ) error("Failed to open %s: %s\n", args->output_fname, strerror(errno)); + + // print header + args->str.l = 0; + ksprintf(&args->str, "# This file was produced by: bcftools roh(%s+htslib-%s)\n", bcftools_version(),hts_version()); + ksprintf(&args->str, "# The command line was:\tbcftools %s", args->argv[0]); + for (i=1; iargc; i++) + ksprintf(&args->str, " %s",args->argv[i]); + ksprintf(&args->str, "\n#\n"); + if ( args->output_type & OUTPUT_RG ) + { + i = 2; + ksprintf(&args->str, "# RG"); + ksprintf(&args->str, "\t[%d]Sample", i++); + ksprintf(&args->str, "\t[%d]Chromosome", i++); + ksprintf(&args->str, "\t[%d]Start", i++); + ksprintf(&args->str, "\t[%d]End", i++); + ksprintf(&args->str, "\t[%d]Length (bp)", i++); + ksprintf(&args->str, "\t[%d]Number of markers", i++); + ksprintf(&args->str, "\t[%d]Quality (average fwd-bwd phred score)", i++); + ksprintf(&args->str, "\n"); + } + if ( args->output_type & OUTPUT_ST ) + { + i = 2; + ksprintf(&args->str, "# ST"); + ksprintf(&args->str, "\t[%d]Sample", i++); + ksprintf(&args->str, "\t[%d]Chromosome", i++); + ksprintf(&args->str, "\t[%d]Position", i++); + ksprintf(&args->str, "\t[%d]State (0:HW, 1:AZ)", i++); + ksprintf(&args->str, "\t[%d]Quality (fwd-bwd phred score)", i++); + ksprintf(&args->str, "\n"); + } + if ( args->vi_training) + { + i = 2; + ksprintf(&args->str, "# VT, Viterbi Training"); + ksprintf(&args->str, "\t[%d]Sample", i++); + ksprintf(&args->str, "\t[%d]Iteration", i++); + ksprintf(&args->str, "\t[%d]dAZ", i++); + ksprintf(&args->str, "\t[%d]dHW", i++); + ksprintf(&args->str, "\t[%d]1 - P(HW|HW)", i++); + ksprintf(&args->str, "\t[%d]P(AZ|HW)", i++); + ksprintf(&args->str, "\t[%d]1 - P(AZ|AZ)", i++); + ksprintf(&args->str, "\t[%d]P(HW|AZ)", i++); + ksprintf(&args->str, "\n"); + } + if ( bgzf_write(args->out, args->str.s, args->str.l) != args->str.l ) + error("Error writing %s: %s\n", args->output_fname, strerror(errno)); +} + +static void destroy_data(args_t *args) +{ + if ( bgzf_close(args->out)!=0 ) error("Error: close failed .. %s\n", args->output_fname); + int i; + for (i=0; iroh_smpl->n; i++) + { + free(args->smpl[i].eprob); + free(args->smpl[i].sites); + free(args->smpl[i].rid); + free(args->smpl[i].rid_off); + free(args->smpl[i].snapshot); + } + free(args->str.s); + free(args->smpl); + if ( args->af_smpl ) smpl_ilist_destroy(args->af_smpl); + smpl_ilist_destroy(args->roh_smpl); + free(args->rids); + free(args->rid_offs); + hmm_destroy(args->hmm); + bcf_sr_destroy(args->files); + free(args->AFs); free(args->pdg); + free(args->genmap); + free(args->itmp); + free(args->samples); +} + +static int load_genmap(args_t *args, bcf1_t *line) +{ + if ( !args->genmap_fname ) { args->ngenmap = 0; return 0; } + + kstring_t str = {0,0,0}; + char *fname = strstr(args->genmap_fname,"{CHROM}"); + if ( fname ) + { + kputsn(args->genmap_fname, fname - args->genmap_fname, &str); + kputs(bcf_seqname(args->hdr,line), &str); + kputs(fname+7,&str); + fname = str.s; + } + else + fname = args->genmap_fname; + + htsFile *fp = hts_open(fname, "rb"); + if ( !fp ) + { + args->ngenmap = 0; + return -1; + } + + hts_getline(fp, KS_SEP_LINE, &str); + if ( strcmp(str.s,"position COMBINED_rate(cM/Mb) Genetic_Map(cM)") ) + error("Unexpected header, found:\n\t[%s], but expected:\n\t[position COMBINED_rate(cM/Mb) Genetic_Map(cM)]\n", fname, str.s); + + args->ngenmap = args->igenmap = 0; + while ( hts_getline(fp, KS_SEP_LINE, &str) > 0 ) + { + args->ngenmap++; + hts_expand(genmap_t,args->ngenmap,args->mgenmap,args->genmap); + genmap_t *gm = &args->genmap[args->ngenmap-1]; + + // position, convert to 0-based + char *tmp, *end; + gm->pos = strtol(str.s, &tmp, 10); + if ( str.s==tmp ) error("Could not parse %s: %s\n", fname, str.s); + gm->pos -= 1; + + // skip second column + tmp++; + while ( *tmp && !isspace(*tmp) ) tmp++; + + // read the genetic map in cM, scale from % to likelihood + gm->rate = strtod(tmp+1, &end); + if ( tmp+1==end ) error("Could not parse %s: %s\n", fname, str.s); + gm->rate *= 0.01; + } + if ( !args->ngenmap ) error("Genetic map empty?\n"); + if ( hts_close(fp) ) error("Close failed\n"); + free(str.s); + return 0; +} + +static double get_genmap_rate(args_t *args, int start, int end) +{ + // position i to be equal to or smaller than start + int i = args->igenmap; + if ( args->genmap[i].pos > start ) + { + while ( i>0 && args->genmap[i].pos > start ) i--; + } + else + { + while ( i+1ngenmap && args->genmap[i+1].pos < start ) i++; + } + // position j to be equal or larger than end + int j = i; + while ( j+1ngenmap && args->genmap[j].pos < end ) j++; + if ( i==j ) + { + args->igenmap = i; + return 0; + } + + if ( start < args->genmap[i].pos ) start = args->genmap[i].pos; + if ( end > args->genmap[j].pos ) end = args->genmap[j].pos; + double rate = (args->genmap[j].rate - args->genmap[i].rate)/(args->genmap[j].pos - args->genmap[i].pos) * (end-start); + args->igenmap = j; + return rate; +} + +void set_tprob_genmap(hmm_t *hmm, uint32_t prev_pos, uint32_t pos, void *data, double *tprob) +{ + args_t *args = (args_t*) data; + double ci = get_genmap_rate(args, prev_pos, pos); + if ( args->rec_rate ) ci *= args->rec_rate; + if ( ci > 1 ) ci = 1; + MAT(tprob,2,STATE_HW,STATE_AZ) *= ci; + MAT(tprob,2,STATE_AZ,STATE_HW) *= ci; + MAT(tprob,2,STATE_AZ,STATE_AZ) = 1 - MAT(tprob,2,STATE_HW,STATE_AZ); + MAT(tprob,2,STATE_HW,STATE_HW) = 1 - MAT(tprob,2,STATE_AZ,STATE_HW); +} + +void set_tprob_rrate(hmm_t *hmm, uint32_t prev_pos, uint32_t pos, void *data, double *tprob) +{ + args_t *args = (args_t*) data; + double ci = (pos - prev_pos) * args->rec_rate; + if ( ci > 1 ) ci = 1; + MAT(tprob,2,STATE_HW,STATE_AZ) *= ci; + MAT(tprob,2,STATE_AZ,STATE_HW) *= ci; + MAT(tprob,2,STATE_AZ,STATE_AZ) = 1 - MAT(tprob,2,STATE_HW,STATE_AZ); + MAT(tprob,2,STATE_HW,STATE_HW) = 1 - MAT(tprob,2,STATE_AZ,STATE_HW); +} + + +/** + * This function implements the HMM model: + * D = Data, AZ = autozygosity, HW = Hardy-Weinberg (non-autozygosity), + * f = non-ref allele frequency + * + * Emission probabilities: + * oAZ = P_i(D|AZ) = (1-f)*P(D|RR) + f*P(D|AA) + * oHW = P_i(D|HW) = (1-f)^2 * P(D|RR) + f^2 * P(D|AA) + 2*f*(1-f)*P(D|RA) + * + * Transition probabilities: + * tAZ = P(AZ|HW) .. parameter + * tHW = P(HW|AZ) .. parameter + * + * ci = P_i(C) .. probability of cross-over at site i, from genetic map + * + * AZi = P_i(AZ) .. probability of site i being AZ/non-AZ, scaled so that AZi+HWi = 1 + * HWi = P_i(HW) + * + * P_i(AZ|HW) = P(AZ|HW) * ci * HW{i-1} = tAZ * ci * (1 - AZ{i-1}) + * P_i(HW|AZ) = P(HW|AZ) * ci * AZ{i-1} = tHW * ci * AZ{i-1} + * P_i(AZ|AZ) = 1 - P_i(HW|AZ) + * P_i(HW|HW) = 1 - P_i(AZ|HW) + * + */ + +static void flush_viterbi(args_t *args, int ismpl) +{ + smpl_t *smpl = &args->smpl[ismpl]; + if ( !smpl->nsites ) return; + + const char *name = args->hdr->samples[ args->roh_smpl->idx[ismpl] ]; + + int i,j,k; + + if ( !args->vi_training ) // single viterbi pass + { + hmm_restore(args->hmm, smpl->snapshot); + int end = (args->nbuf_max && smpl->nsites >= args->nbuf_max && smpl->nsites > args->nbuf_olap) ? smpl->nsites - args->nbuf_olap : smpl->nsites; + if ( end < smpl->nsites ) + smpl->snapshot = hmm_snapshot(args->hmm, smpl->snapshot, smpl->nsites - args->nbuf_olap - 1); + + args->igenmap = smpl->igenmap; + hmm_run_viterbi(args->hmm, smpl->nsites, smpl->eprob, smpl->sites); + hmm_run_fwd_bwd(args->hmm, smpl->nsites, smpl->eprob, smpl->sites); + double *fwd = hmm_get_fwd_bwd_prob(args->hmm); + + const char *chr = bcf_hdr_id2name(args->hdr,args->prev_rid); + uint8_t *vpath = hmm_get_viterbi_path(args->hmm); + + for (i=0; ioutput_type & OUTPUT_ST ) + { + args->str.l = 0; + ksprintf(&args->str, "ST\t%s\t%s\t%d\t%d\t%.1f\n", name,chr,smpl->sites[i]+1, state, qual); + if ( bgzf_write(args->out, args->str.s, args->str.l) != args->str.l ) error("Error writing %s: %s\n", args->output_fname, strerror(errno)); + } + + if ( args->output_type & OUTPUT_RG ) + { + if ( state!=smpl->rg.state ) + { + if ( !state ) // the region ends, flush + { + args->str.l = 0; + ksprintf(&args->str, "RG\t%s\t%s\t%d\t%d\t%d\t%d\t%.1f\n",name,bcf_hdr_id2name(args->hdr,smpl->rg.rid), + smpl->rg.beg+1,smpl->rg.end+1,smpl->rg.end-smpl->rg.beg+1,smpl->rg.nqual,smpl->rg.qual/smpl->rg.nqual); + if ( bgzf_write(args->out, args->str.s, args->str.l) != args->str.l ) error("Error writing %s: %s\n", args->output_fname, strerror(errno)); + smpl->rg.state = 0; + } + else + { + smpl->rg.state = 1; + smpl->rg.beg = smpl->sites[i]; + smpl->rg.rid = args->prev_rid; + } + } + else if ( state ) + { + smpl->rg.nqual++; + smpl->rg.qual += qual; + smpl->rg.end = smpl->sites[i]; + } + } + } + + if ( end < smpl->nsites ) + { + end = smpl->nsites - args->nbuf_olap; + memmove(smpl->sites, smpl->sites + end, sizeof(*smpl->sites)*args->nbuf_olap); + memmove(smpl->eprob, smpl->eprob + end*2, sizeof(*smpl->eprob)*args->nbuf_olap*2); + smpl->nsites = args->nbuf_olap; + smpl->igenmap = args->igenmap; + } + else + { + smpl->nsites = 0; + smpl->igenmap = 0; + + if ( smpl->rg.state ) + { + args->str.l = 0; + ksprintf(&args->str, "RG\t%s\t%s\t%d\t%d\t%d\t%d\t%.1f\n",name,bcf_hdr_id2name(args->hdr,smpl->rg.rid), + smpl->rg.beg+1,smpl->rg.end+1,smpl->rg.end-smpl->rg.beg+1,smpl->rg.nqual,smpl->rg.qual/smpl->rg.nqual); + if ( bgzf_write(args->out, args->str.s, args->str.l) != args->str.l ) error("Error writing %s: %s\n", args->output_fname, strerror(errno)); + smpl->rg.state = 0; + } + } + + return; + } + + + // viterbi training, multiple chromosomes + double t2az_prev, t2hw_prev; + double deltaz, delthw; + + double *tprob_arr = hmm_get_tprob(args->hmm); + MAT(tprob_arr,2,STATE_HW,STATE_HW) = 1 - args->t2AZ; + MAT(tprob_arr,2,STATE_HW,STATE_AZ) = args->t2HW; + MAT(tprob_arr,2,STATE_AZ,STATE_HW) = args->t2AZ; + MAT(tprob_arr,2,STATE_AZ,STATE_AZ) = 1 - args->t2HW; + hmm_set_tprob(args->hmm, tprob_arr, 10000); + + int niter = 0; + do + { + tprob_arr = hmm_get_tprob(args->hmm); + t2az_prev = MAT(tprob_arr,2,STATE_AZ,STATE_HW); //args->t2AZ; + t2hw_prev = MAT(tprob_arr,2,STATE_HW,STATE_AZ); //args->t2HW; + double tprob_new[] = { 0,0,0,0 }; + for (i=0; inrid; i++) + { + int ioff = smpl->rid_off[i]; + int nsites = (i+1==smpl->nrid ? smpl->nsites : smpl->rid_off[i+1]) - ioff; + args->igenmap = 0; + tprob_arr = hmm_run_baum_welch(args->hmm, nsites, smpl->eprob+ioff*2, smpl->sites+ioff); + for (j=0; j<2; j++) + for (k=0; k<2; k++) MAT(tprob_new,2,j,k) += MAT(tprob_arr,2,j,k); + } + for (j=0; j<2; j++) + for (k=0; k<2; k++) MAT(tprob_new,2,j,k) /= smpl->nrid; + + hmm_set_tprob(args->hmm, tprob_new, 10000); + + deltaz = fabs(MAT(tprob_new,2,STATE_AZ,STATE_HW)-t2az_prev); + delthw = fabs(MAT(tprob_new,2,STATE_HW,STATE_AZ)-t2hw_prev); + niter++; + args->str.l = 0; + ksprintf(&args->str, "VT\t%s\t%d\t%e\t%e\t%e\t%e\t%e\t%e\n", + name,niter,deltaz,delthw, + 1-MAT(tprob_new,2,STATE_HW,STATE_HW),MAT(tprob_new,2,STATE_AZ,STATE_HW), + 1-MAT(tprob_new,2,STATE_AZ,STATE_AZ),MAT(tprob_new,2,STATE_HW,STATE_AZ)); + if ( bgzf_write(args->out, args->str.s, args->str.l) != args->str.l ) error("Error writing %s: %s\n", args->output_fname, strerror(errno)); + } + while ( deltaz > args->baum_welch_th || delthw > args->baum_welch_th ); + + // output the results + for (i=0; inrid; i++) + { + int ioff = smpl->rid_off[i]; + int nsites = (i+1==smpl->nrid ? smpl->nsites : smpl->rid_off[i+1]) - ioff; + args->igenmap = 0; + hmm_run_viterbi(args->hmm, nsites, smpl->eprob+ioff*2, smpl->sites+ioff); + hmm_run_fwd_bwd(args->hmm, nsites, smpl->eprob+ioff*2, smpl->sites+ioff); + uint8_t *vpath = hmm_get_viterbi_path(args->hmm); + double *fwd = hmm_get_fwd_bwd_prob(args->hmm); + + const char *chr = bcf_hdr_id2name(args->hdr,smpl->rid[i]); + for (j=0; jstr.l = 0; + ksprintf(&args->str, "ROH\t%s\t%s\t%d\t%d\t%.1f\n", name,chr,smpl->sites[ioff+j]+1, state, phred_score(1.0-pval[state])); + if ( bgzf_write(args->out, args->str.s, args->str.l) != args->str.l ) error("Error writing %s: %s\n", args->output_fname, strerror(errno)); + } + } +} + + +int read_AF(bcf_sr_regions_t *tgt, bcf1_t *line, double *alt_freq) +{ + if ( tgt->nals != line->n_allele ) return -1; // number of alleles does not match + + int i; + for (i=0; inals; i++) + if ( strcmp(line->d.allele[i],tgt->als[i]) ) break; // we could be smarter, see vcmp + if ( inals ) return -1; + + char *tmp, *str = tgt->line.s; + i = 0; + while ( *str && i<3 ) + { + if ( *str=='\t' ) i++; + str++; + } + *alt_freq = strtod(str, &tmp); + if ( *tmp && !isspace(*tmp) ) + { + if ( str[0]=='.' && (!str[1] || isspace(str[1])) ) return -1; // missing value + error("Could not parse: [%s]\n", tgt->line.s); + } + if ( *alt_freq<0 || *alt_freq>1 ) error("Could not parse AF: [%s]\n", tgt->line.s); + return 0; +} + +int8_t *get_GT(args_t *args, bcf1_t *line) +{ + int i; + for (i=0; in_fmt; i++) + if ( line->d.fmt[i].id==args->gt_hdr_id ) break; + if ( i==line->n_fmt ) return NULL; // the tag is not present in this record + + bcf_fmt_t *fmt = &line->d.fmt[i]; + if ( fmt->n!=2 ) return NULL; // not diploid + + if ( fmt->type!=BCF_BT_INT8 ) error("This is unexpected, GT type is %d\n", fmt->type); + return (int8_t*) fmt->p; +} + +int estimate_AF_from_GT(args_t *args, int8_t *gt, double *alt_freq) +{ + int i, nalt = 0, nref = 0; + if ( args->af_smpl ) // subset samples for AF estimate + { + for (i=0; iaf_smpl->n; i++) + { + int ismpl = args->af_smpl->idx[i]; + if ( bcf_gt_is_missing(gt[2*ismpl]) || bcf_gt_is_missing(gt[2*ismpl+1]) ) continue; + + if ( bcf_gt_allele(gt[2*ismpl]) ) nalt++; + else nref++; + + if ( bcf_gt_allele(gt[2*ismpl+1]) ) nalt++; + else nref++; + } + } + else // all samples used in AF estimate + { + int8_t *end = gt + 2*bcf_hdr_nsamples(args->hdr); + while ( gt < end ) + { + if ( bcf_gt_is_missing(gt[0]) || bcf_gt_is_missing(gt[1]) ) continue; + + if ( bcf_gt_allele(gt[0]) ) nalt++; + else nref++; + + if ( bcf_gt_allele(gt[1]) ) nalt++; + else nref++; + + gt += 2; + } + } + if ( !nalt && !nref ) return -1; + + *alt_freq = (double)nalt / (nalt + nref); + return 0; +} + +int estimate_AF_from_PL(args_t *args, bcf_fmt_t *fmt_pl, int ial, double *alt_freq) +{ + double af = 0; + int i, j, naf = 0; + + int irr = bcf_alleles2gt(0,0), ira = bcf_alleles2gt(0,ial), iaa = bcf_alleles2gt(ial,ial); + if ( iaa >= fmt_pl->n ) return -1; // not diploid or wrong number of fields + + if ( args->af_smpl ) // subset samples for AF estimate + { + #define BRANCH(type_t) \ + { \ + for (i=0; iaf_smpl->n; i++) \ + { \ + int ismpl = args->af_smpl->idx[i]; \ + type_t *p = (type_t*)fmt_pl->p + fmt_pl->n*ismpl; \ + if ( p[irr]<0 || p[ira]<0 || p[iaa]<0 ) continue; /* missing value */ \ + if ( p[irr]==p[ira] && p[irr]==p[iaa] ) continue; /* all values are the same */ \ + double prob[3], norm = 0; \ + prob[0] = p[irr] < (type_t)256 ? args->pl2p[ p[irr] ] : args->pl2p[255]; \ + prob[1] = p[ira] < (type_t)256 ? args->pl2p[ p[ira] ] : args->pl2p[255]; \ + prob[2] = p[iaa] < (type_t)256 ? args->pl2p[ p[iaa] ] : args->pl2p[255]; \ + for (j=0; j<3; j++) norm += prob[j]; \ + for (j=0; j<3; j++) prob[j] /= norm; \ + af += 0.5*prob[1] + prob[2]; \ + naf++; \ + } \ + } + switch (fmt_pl->type) { + case BCF_BT_INT8: BRANCH(int8_t); break; + case BCF_BT_INT16: BRANCH(int16_t); break; + case BCF_BT_INT32: BRANCH(int32_t); break; + default: fprintf(stderr,"Unknown format type for PL: %s:%d .. fmt->type=%d\n", __FILE__,__LINE__, fmt_pl->type); exit(1); + } + #undef BRANCH + } + else // all samples used in AF estimate + { + int nsmpl = bcf_hdr_nsamples(args->hdr); + #define BRANCH(type_t) \ + { \ + type_t *p = (type_t*)fmt_pl->p; \ + p -= fmt_pl->n; \ + for (i=0; in; \ + if ( p[irr]<0 || p[ira]<0 || p[iaa]<0 ) continue; /* missing value */ \ + if ( p[irr]==p[ira] && p[irr]==p[iaa] ) continue; /* all values are the same */ \ + double prob[3], norm = 0; \ + prob[0] = p[irr] < (type_t)256 ? args->pl2p[ p[irr] ] : args->pl2p[255]; \ + prob[1] = p[ira] < (type_t)256 ? args->pl2p[ p[ira] ] : args->pl2p[255]; \ + prob[2] = p[iaa] < (type_t)256 ? args->pl2p[ p[iaa] ] : args->pl2p[255]; \ + for (j=0; j<3; j++) norm += prob[j]; \ + for (j=0; j<3; j++) prob[j] /= norm; \ + af += 0.5*prob[1] + prob[2]; \ + naf++; \ + } \ + } + switch (fmt_pl->type) { + case BCF_BT_INT8: BRANCH(int8_t); break; + case BCF_BT_INT16: BRANCH(int16_t); break; + case BCF_BT_INT32: BRANCH(int32_t); break; + default: fprintf(stderr,"Unknown format type for PL: %s:%d .. fmt->type=%d\n", __FILE__,__LINE__, fmt_pl->type); exit(1); + } + #undef BRANCH + } + if ( !naf ) return -1; + + *alt_freq = af / naf; + return 0; +} + +bcf_fmt_t *get_PL(args_t *args, bcf1_t *line) +{ + int i; + for (i=0; in_fmt; i++) + if ( line->d.fmt[i].id==args->pl_hdr_id ) return &line->d.fmt[i]; + return NULL; +} + +int process_line(args_t *args, bcf1_t *line, int ial) +{ + if ( !(line->unpacked & BCF_UN_FMT) ) bcf_unpack(line, BCF_UN_FMT); + + double alt_freq; + int8_t *GTs = NULL; + bcf_fmt_t *fmt_pl = NULL; + + // Set allele frequency + int ret = 0, i,j; + if ( args->af_tag ) + { + // Use an INFO tag provided by the user + ret = bcf_get_info_float(args->hdr, line, args->af_tag, &args->AFs, &args->mAFs); + if ( ret>0 ) + alt_freq = args->AFs[ial-1]; + if ( ret==-2 ) + error("Type mismatch for INFO/%s tag at %s:%d\n", args->af_tag, bcf_seqname(args->hdr,line), line->pos+1); + } + else if ( args->af_fname ) + { + // Read AF from a file + ret = read_AF(args->files->targets, line, &alt_freq); + } + else if ( args->dflt_AF > 0 ) + { + alt_freq = args->dflt_AF; + } + else if ( args->estimate_AF ) + { + // Estimate AF from GTs or PLs of all samples or samples listed in a file + if ( args->af_from_PL ) + { + fmt_pl = get_PL(args, line); + if ( !fmt_pl ) return -1; + ret = estimate_AF_from_PL(args, fmt_pl, ial, &alt_freq); + } + else + { + GTs = get_GT(args, line); + if ( !GTs ) return -1; + ret = estimate_AF_from_GT(args, GTs, &alt_freq); + } + } + else + { + // Use AC/AN + int AC = -1, AN = 0; + ret = bcf_get_info_int32(args->hdr, line, "AN", &args->itmp, &args->mitmp); + if ( ret==1 ) + { + AN = args->itmp[0]; + ret = bcf_get_info_int32(args->hdr, line, "AC", &args->itmp, &args->mitmp); + if ( ret>0 ) + AC = args->itmp[0]; + } + if ( AN<=0 || AC<0 ) + ret = -1; + else + alt_freq = (double) AC/AN; + } + + if ( ret<0 ) return ret; + if ( alt_freq==0.0 ) return -1; + + int irr = bcf_alleles2gt(0,0), ira = bcf_alleles2gt(0,ial), iaa = bcf_alleles2gt(ial,ial); + if ( args->fake_PLs ) + { + if ( !GTs ) GTs = get_GT(args, line); + } + else + { + fmt_pl = get_PL(args, line); + if ( !fmt_pl ) return -1; + if ( iaa >= fmt_pl->n ) return -1; // not diploid or wrong number of fields + } + + for (i=0; iroh_smpl->n; i++) + { + int ismpl = args->roh_smpl->idx[i]; + + // set P(D|G) + double pdg[3]; + if ( args->fake_PLs ) + { + int8_t *gt = GTs + 2*ismpl; + if ( bcf_gt_is_missing(gt[0]) || bcf_gt_is_missing(gt[1]) ) continue; + + int a = bcf_gt_allele(gt[0]); + int b = bcf_gt_allele(gt[1]); + if ( a!=b ) + { + pdg[0] = pdg[2] = args->unseen_PL; + pdg[1] = 1 - 2*args->unseen_PL; + } + else if ( a==0 ) + { + pdg[0] = 1 - args->unseen_PL - args->unseen_PL*args->unseen_PL; + pdg[1] = args->unseen_PL; + pdg[2] = args->unseen_PL*args->unseen_PL; + } + else + { + pdg[0] = args->unseen_PL*args->unseen_PL; + pdg[1] = args->unseen_PL; + pdg[2] = 1 - args->unseen_PL - args->unseen_PL*args->unseen_PL; + } + } + else + { + #define BRANCH(type_t) \ + { \ + type_t *p = (type_t*)fmt_pl->p + fmt_pl->n*ismpl; \ + if ( p[irr]<0 || p[ira]<0 || p[iaa]<0 ) continue; /* missing value */ \ + if ( p[irr]==p[ira] && p[irr]==p[iaa] ) continue; /* all values are the same */ \ + pdg[0] = p[irr] < (type_t)256 ? args->pl2p[ p[irr] ] : args->pl2p[255]; \ + pdg[1] = p[ira] < (type_t)256 ? args->pl2p[ p[ira] ] : args->pl2p[255]; \ + pdg[2] = p[iaa] < (type_t)256 ? args->pl2p[ p[iaa] ] : args->pl2p[255]; \ + } + switch (fmt_pl->type) { + case BCF_BT_INT8: BRANCH(int8_t); break; + case BCF_BT_INT16: BRANCH(int16_t); break; + case BCF_BT_INT32: BRANCH(int32_t); break; + default: fprintf(stderr,"Unknown format type for PL: %s:%d .. fmt->type=%d\n", __FILE__,__LINE__, fmt_pl->type); exit(1); + } + #undef BRANCH + } + + double sum = pdg[0] + pdg[1] + pdg[2]; + if ( !sum ) continue; + for (j=0; j<3; j++) pdg[j] /= sum; + if ( args->skip_homref && pdg[0]>0.99 ) continue; + + smpl_t *smpl = &args->smpl[i]; + smpl->nused++; + + if ( smpl->nsites >= smpl->msites ) + { + hts_expand(uint32_t,smpl->nsites+1,smpl->msites,smpl->sites); + smpl->eprob = (double*) realloc(smpl->eprob,sizeof(*smpl->eprob)*smpl->msites*2); + if ( !smpl->eprob ) error("Error: failed to alloc %d bytes\n", sizeof(*smpl->eprob)*smpl->msites*2); + } + + // Calculate emission probabilities P(D|AZ) and P(D|HW) + double *eprob = &smpl->eprob[2*smpl->nsites]; + eprob[STATE_AZ] = pdg[0]*(1-alt_freq) + pdg[2]*alt_freq; + eprob[STATE_HW] = pdg[0]*(1-alt_freq)*(1-alt_freq) + 2*pdg[1]*(1-alt_freq)*alt_freq + pdg[2]*alt_freq*alt_freq; + + smpl->sites[smpl->nsites] = line->pos; + smpl->nsites++; + + if ( args->vi_training ) + { + if ( !smpl->nrid || line->rid!=smpl->rid[smpl->nrid-1] ) + { + smpl->nrid++; + smpl->rid = (int*) realloc(smpl->rid,sizeof(*smpl->rid)*smpl->nrid); + smpl->rid[smpl->nrid-1] = line->rid; + smpl->rid_off = (int*) realloc(smpl->rid_off,sizeof(*smpl->rid_off)*smpl->nrid); + smpl->rid_off[smpl->nrid-1] = smpl->nsites - 1; + } + } + else if ( args->nbuf_max && smpl->nsites >= args->nbuf_max ) flush_viterbi(args, i); + } + + return 0; +} + +static void vcfroh(args_t *args, bcf1_t *line) +{ + int i; + + // Are we done? + if ( !line ) + { + for (i=0; iroh_smpl->n; i++) flush_viterbi(args, i); + return; + } + args->ntot++; + + // Skip unwanted lines, for simplicity we consider only biallelic sites + if ( line->rid == args->skip_rid ) return; + if ( line->n_allele==1 ) return; // no ALT allele + if ( line->n_allele > 3 ) return; // cannot be bi-allelic, even with <*> + + // This can be raw callable VCF with the symbolic unseen allele <*> + int ial = 0; + for (i=1; in_allele; i++) + if ( !strcmp("<*>",line->d.allele[i]) ) { ial = i; break; } + if ( ial==0 ) // normal VCF, the symbolic allele is not present + { + if ( line->n_allele!=2 ) return; // not biallelic + ial = 1; + } + else + { + if ( line->n_allele!=3 ) return; // not biallelic + ial = ial==1 ? 2 : 1; // <*> can come in any order + } + if ( args->snps_only && !bcf_is_snp(line) ) return; + + // Initialize genetic map + int skip_rid = 0; + if ( args->prev_rid<0 ) + { + args->prev_rid = line->rid; + args->prev_pos = line->pos; + skip_rid = load_genmap(args, line); + } + + // New chromosome? + if ( args->prev_rid!=line->rid ) + { + skip_rid = load_genmap(args, line); + if ( !args->vi_training ) + { + for (i=0; iroh_smpl->n; i++) flush_viterbi(args, i); + } + args->prev_rid = line->rid; + args->prev_pos = line->pos; + } + + if ( skip_rid ) + { + fprintf(stderr,"Skipping the sequence, no genmap for %s\n", bcf_seqname(args->hdr,line)); + args->skip_rid = line->rid; + return; + } + if ( args->prev_pos > line->pos ) error("The file is not sorted?!\n"); + + args->prev_rid = line->rid; + args->prev_pos = line->pos; + + + // parse the new line + process_line(args, line, ial); +} + +static void usage(args_t *args) +{ + fprintf(stderr, "\n"); + fprintf(stderr, "About: HMM model for detecting runs of autozygosity.\n"); + fprintf(stderr, "Usage: bcftools roh [options] \n"); + fprintf(stderr, "\n"); + fprintf(stderr, "General Options:\n"); + fprintf(stderr, " --AF-dflt if AF is not known, use this allele frequency [skip]\n"); + fprintf(stderr, " --AF-tag use TAG for allele frequency\n"); + fprintf(stderr, " --AF-file read allele frequencies from file (CHR\\tPOS\\tREF,ALT\\tAF)\n"); + fprintf(stderr, " -b --buffer-size buffer size and the number of overlapping sites, 0 for unlimited [0]\n"); + fprintf(stderr, " If the first number is negative, it is interpreted as the maximum memory to\n"); + fprintf(stderr, " use, in MB. The default overlap is set to roughly 1%% of the buffer size.\n"); + fprintf(stderr, " -e, --estimate-AF [TAG], estimate AF from FORMAT/TAG (GT or PL) of all samples (\"-\") or samples listed\n"); + fprintf(stderr, " in . If TAG is not given, the frequency is estimated from GT by default\n"); + fprintf(stderr, " -G, --GTs-only use GTs and ignore PLs, instead using for PL of the two least likely genotypes.\n"); + fprintf(stderr, " Safe value to use is 30 to account for GT errors.\n"); + fprintf(stderr, " -i, --ignore-homref skip hom-ref genotypes (0/0)\n"); + fprintf(stderr, " -I, --skip-indels skip indels as their genotypes are enriched for errors\n"); + fprintf(stderr, " -m, --genetic-map genetic map in IMPUTE2 format, single file or mask, where string \"{CHROM}\"\n"); + fprintf(stderr, " is replaced with chromosome name\n"); + fprintf(stderr, " -M, --rec-rate constant recombination rate per bp\n"); + fprintf(stderr, " -o, --output write output to a file [standard output]\n"); + fprintf(stderr, " -O, --output-type [srz] output s:per-site, r:regions, z:compressed [sr]\n"); + fprintf(stderr, " -r, --regions restrict to comma-separated list of regions\n"); + fprintf(stderr, " -R, --regions-file restrict to regions listed in a file\n"); + fprintf(stderr, " -s, --samples list of samples to analyze [all samples]\n"); + fprintf(stderr, " -S, --samples-file file of samples to analyze [all samples]\n"); + fprintf(stderr, " -t, --targets similar to -r but streams rather than index-jumps\n"); + fprintf(stderr, " -T, --targets-file similar to -R but streams rather than index-jumps\n"); + fprintf(stderr, " --threads number of extra decompression threads [0]\n"); + fprintf(stderr, "\n"); + fprintf(stderr, "HMM Options:\n"); + fprintf(stderr, " -a, --hw-to-az P(AZ|HW) transition probability from HW (Hardy-Weinberg) to AZ (autozygous) state [6.7e-8]\n"); + fprintf(stderr, " -H, --az-to-hw P(HW|AZ) transition probability from AZ to HW state [5e-9]\n"); + fprintf(stderr, " -V, --viterbi-training estimate HMM parameters, is the convergence threshold, e.g. 1e-10 (experimental)\n"); + fprintf(stderr, "\n"); + exit(1); +} + +int main_vcfroh(int argc, char *argv[]) +{ + int c; + args_t *args = (args_t*) calloc(1,sizeof(args_t)); + args->argc = argc; args->argv = argv; + args->files = bcf_sr_init(); + args->t2AZ = 6.7e-8; + args->t2HW = 5e-9; + args->rec_rate = 0; + int regions_is_file = 0, targets_is_file = 0; + + static struct option loptions[] = + { + {"AF-tag",1,0,0}, + {"AF-file",1,0,1}, + {"AF-dflt",1,0,2}, + {"buffer-size",1,0,'b'}, + {"ignore-homref",0,0,'i'}, + {"estimate-AF",1,0,'e'}, + {"output",1,0,'o'}, + {"output-type",1,0,'O'}, + {"GTs-only",1,0,'G'}, + {"samples",1,0,'s'}, + {"samples-file",1,0,'S'}, + {"hw-to-az",1,0,'a'}, + {"az-to-hw",1,0,'H'}, + {"viterbi-training",1,0,'V'}, + {"targets",1,0,'t'}, + {"targets-file",1,0,'T'}, + {"regions",1,0,'r'}, + {"regions-file",1,0,'R'}, + {"genetic-map",1,0,'m'}, + {"rec-rate",1,0,'M'}, + {"skip-indels",0,0,'I'}, + {"threads",1,0,9}, + {0,0,0,0} + }; + + int naf_opts = 0; + char *tmp; + while ((c = getopt_long(argc, argv, "h?r:R:t:T:H:a:s:S:m:M:G:Ia:e:V:b:O:o:i",loptions,NULL)) >= 0) { + switch (c) { + case 0: args->af_tag = optarg; naf_opts++; break; + case 1: args->af_fname = optarg; naf_opts++; break; + case 2: + args->dflt_AF = strtod(optarg,&tmp); + if ( *tmp ) error("Could not parse: --AF-dflt %s\n", optarg); + break; + case 'o': args->output_fname = optarg; break; + case 'O': + if ( strchr(optarg,'s') || strchr(optarg,'S') ) args->output_type |= OUTPUT_ST; + if ( strchr(optarg,'r') || strchr(optarg,'R') ) args->output_type |= OUTPUT_RG; + if ( strchr(optarg,'z') || strchr(optarg,'z') ) args->output_type |= OUTPUT_GZ; + break; + case 'e': args->estimate_AF = optarg; naf_opts++; break; + case 'b': args->buffer_size = optarg; break; + case 'i': args->skip_homref = 1; break; + case 'I': args->snps_only = 1; break; + case 'G': + args->fake_PLs = 1; + args->unseen_PL = strtod(optarg,&tmp); + if ( *tmp ) error("Could not parse: -G %s\n", optarg); + args->unseen_PL = pow(10,-args->unseen_PL/10.); + break; + case 'm': args->genmap_fname = optarg; break; + case 'M': + args->rec_rate = strtod(optarg,&tmp); + if ( *tmp ) error("Could not parse: -M %s\n", optarg); + break; + case 's': args->samples = strdup(optarg); break; + case 'S': args->samples = strdup(optarg); args->samples_is_file = 1; break; + case 'a': + args->t2AZ = strtod(optarg,&tmp); + if ( *tmp ) error("Could not parse: -a %s\n", optarg); + break; + case 'H': + args->t2HW = strtod(optarg,&tmp); + if ( *tmp ) error("Could not parse: -H %s\n", optarg); + break; + case 't': args->targets_list = optarg; break; + case 'T': args->targets_list = optarg; targets_is_file = 1; break; + case 'r': args->regions_list = optarg; break; + case 'R': args->regions_list = optarg; regions_is_file = 1; break; + case 9 : args->n_threads = strtol(optarg, 0, 0); break; + case 'V': + args->vi_training = 1; + args->baum_welch_th = strtod(optarg,&tmp); + if ( *tmp ) error("Could not parse: --viterbi-training %s\n", optarg); + break; + case 'h': + case '?': usage(args); break; + default: error("Unknown argument: %s\n", optarg); + } + } + if ( !args->output_fname ) args->output_fname = "stdout"; + if ( !args->output_type ) args->output_type = OUTPUT_ST|OUTPUT_RG; + char *fname = NULL; + if ( optind==argc ) + { + if ( !isatty(fileno((FILE *)stdin)) ) fname = "-"; // reading from stdin + else usage(args); + } + else fname = argv[optind]; + + if ( args->vi_training && args->buffer_size ) error("Error: cannot use -b with -V\n"); + if ( args->t2AZ<0 || args->t2AZ>1 ) error("Error: The parameter --hw-to-az is not in [0,1]\n", args->t2AZ); + if ( args->t2HW<0 || args->t2HW>1 ) error("Error: The parameter --az-to-hw is not in [0,1]\n", args->t2HW); + if ( naf_opts>1 ) error("Error: The options --AF-tag, --AF-file and -e are mutually exclusive\n"); + if ( args->af_fname && args->targets_list ) error("Error: The options --AF-file and -t are mutually exclusive\n"); + if ( args->regions_list ) + { + if ( bcf_sr_set_regions(args->files, args->regions_list, regions_is_file)<0 ) + error("Failed to read the regions: %s\n", args->regions_list); + } + if ( args->targets_list ) + { + if ( bcf_sr_set_targets(args->files, args->targets_list, targets_is_file, 0)<0 ) + error("Failed to read the targets: %s\n", args->targets_list); + } + if ( args->af_fname ) + { + if ( bcf_sr_set_targets(args->files, args->af_fname, 1, 3)<0 ) + error("Failed to read the targets: %s\n", args->af_fname); + } + if ( args->n_threads && bcf_sr_set_threads(args->files, args->n_threads)<0) + error("Failed to create threads\n"); + if ( !bcf_sr_add_reader(args->files, fname) ) error("Failed to open %s: %s\n", fname,bcf_sr_strerror(args->files->errnum)); + + init_data(args); + while ( bcf_sr_next_line(args->files) ) + { + vcfroh(args, args->files->readers[0].buffer[0]); + } + vcfroh(args, NULL); + int i, nmin = 0; + for (i=0; iroh_smpl->n; i++) + if ( !i || args->smpl[i].nused < nmin ) nmin = args->smpl[i].nused; + fprintf(stderr,"Number of lines total/processed: %d/%d\n", args->ntot,nmin); + if ( nmin==0 ) + { + fprintf(stderr,"No usable sites were found."); + if ( !naf_opts && !args->dflt_AF ) fprintf(stderr, " Consider using one of the AF options.\n"); + } + destroy_data(args); + free(args); + return 0; +} + + diff --git a/vcfsom.c b/vcfsom.c new file mode 100644 index 0000000..03181e9 --- /dev/null +++ b/vcfsom.c @@ -0,0 +1,715 @@ +/* vcfsom.c -- SOM (Self-Organizing Map) filtering. + + Copyright (C) 2013-2014 Genome Research Ltd. + + Author: Petr Danecek + +Permission is hereby granted, free of charge, to any person obtaining a copy +of this software and associated documentation files (the "Software"), to deal +in the Software without restriction, including without limitation the rights +to use, copy, modify, merge, publish, distribute, sublicense, and/or sell +copies of the Software, and to permit persons to whom the Software is +furnished to do so, subject to the following conditions: + +The above copyright notice and this permission notice shall be included in +all copies or substantial portions of the Software. + +THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE +AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER +LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, +OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN +THE SOFTWARE. */ + +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include "bcftools.h" + +#define SOM_TRAIN 1 +#define SOM_CLASSIFY 2 + +typedef struct +{ + int ndim; // dimension of the map (2D, 3D, ...) + int nbin; // number of bins in th map + int size; // pow(nbin,ndim) + int kdim; // dimension of the input vectors + int nt, t; // total number of learning cycles and the current cycle + double *w, *c; // weights and counts (sum of learning influence) + double learn; // learning rate + double bmu_th; // best-matching unit threshold + int *a_idx, *b_idx; // temp arrays for traversing variable number of nested loops + double *div; // dtto +} +som_t; + +typedef struct +{ + // SOM parameters + double bmu_th, learn; + int ndim, nbin, ntrain, t; + int nfold; // n-fold cross validation = the number of SOMs + som_t **som; + + // annots reader's data + htsFile *file; // reader + kstring_t str; // temporary string for the reader + int dclass, mvals; + double *vals; + + // training data + double *train_dat; + int *train_class, mtrain_class, mtrain_dat; + + int rand_seed, good_class, bad_class; + char **argv, *fname, *prefix; + int argc, action, train_bad, merge; +} +args_t; + +static void usage(void); +FILE *open_file(char **fname, const char *mode, const char *fmt, ...); +void mkdir_p(const char *fmt, ...); + +char *msprintf(const char *fmt, ...) +{ + va_list ap; + va_start(ap, fmt); + int n = vsnprintf(NULL, 0, fmt, ap) + 2; + va_end(ap); + + char *str = (char*)malloc(n); + va_start(ap, fmt); + vsnprintf(str, n, fmt, ap); + va_end(ap); + + return str; +} + +/* + * char *t, *p = str; + * t = column_next(p, '\t'); + * if ( strlen("")==t-p && !strncmp(p,"",t-p) ) printf("found!\n"); + * + * char *t; + * t = column_next(str, '\t'); if ( !*t ) error("expected field\n", str); + * t = column_next(t+1, '\t'); if ( !*t ) error("expected field\n", str); + */ +static inline char *column_next(char *start, char delim) +{ + char *end = start; + while (*end && *end!=delim) end++; + return end; +} +/** + * annots_reader_next() - reads next line from annots.tab.gz and sets: class, vals + * Returns 1 on successful read or 0 if no further record could be read. + */ +int annots_reader_next(args_t *args) +{ + args->str.l = 0; + if ( hts_getline(args->file,'\n',&args->str)<=0 ) return 0; + + char *t, *line = args->str.s; + + if ( !args->mvals ) + { + t = line; + while ( *t ) + { + if ( *t=='\t' ) args->mvals++; + t++; + } + args->vals = (double*) malloc(args->mvals*sizeof(double)); + } + + // class + args->dclass = atoi(line); + t = column_next(line, '\t'); + + // values + int i; + for (i=0; imvals; i++) + { + if ( !*t ) error("Could not parse %d-th data field: is the line truncated?\nThe line was: [%s]\n",i+2,line); + args->vals[i] = atof(++t); + t = column_next(t,'\t'); + } + return 1; +} +void annots_reader_reset(args_t *args) +{ + if ( args->file ) hts_close(args->file); + if ( !args->fname ) error("annots_reader_reset: no fname\n"); + args->file = hts_open(args->fname, "r"); +} +void annots_reader_close(args_t *args) +{ + hts_close(args->file); +} + +static void som_write_map(char *prefix, som_t **som, int nsom) +{ + FILE *fp = open_file(NULL,"w","%s.som",prefix); + fwrite("SOMv1",5,1,fp); + fwrite(&nsom,sizeof(int),1,fp); + int i; + for (i=0; isize,sizeof(int),1,fp); + fwrite(&som[i]->kdim,sizeof(int),1,fp); + fwrite(som[i]->w,sizeof(double),som[i]->size*som[i]->kdim,fp); + fwrite(som[i]->c,sizeof(double),som[i]->size,fp); + } + if ( fclose(fp) ) error("%s.som: fclose failed\n",prefix); +} +static som_t** som_load_map(char *prefix, int *nsom) +{ + FILE *fp = open_file(NULL,"r","%s.som",prefix); + char buf[5]; + if ( fread(buf,5,1,fp)!=1 || strncmp(buf,"SOMv1",5) ) error("Could not parse %s.som\n", prefix); + + if ( fread(nsom,sizeof(int),1,fp)!=1 ) error("Could not read %s.som\n", prefix); + som_t **som = (som_t**)malloc(*nsom*sizeof(som_t*)); + + int i; + for (i=0; i<*nsom; i++) + { + som[i] = (som_t*) calloc(1,sizeof(som_t)); + if ( fread(&som[i]->size,sizeof(int),1,fp) != 1 ) error("Could not read %s.som\n", prefix); + if ( fread(&som[i]->kdim,sizeof(int),1,fp) != 1 ) error("Could not read %s.som\n", prefix); + som[i]->w = (double*) malloc(sizeof(double)*som[i]->size*som[i]->kdim); + som[i]->c = (double*) malloc(sizeof(double)*som[i]->size); + if ( fread(som[i]->w,sizeof(double),som[i]->size*som[i]->kdim,fp) != som[i]->size*som[i]->kdim ) error("Could not read from %s.som\n", prefix); + if ( fread(som[i]->c,sizeof(double),som[i]->size,fp) != som[i]->size ) error("Could not read from %s.som\n", prefix); + } + if ( fclose(fp) ) error("%s.som: fclose failed\n",prefix); + return som; +} +static void som_create_plot(som_t *som, char *prefix) +{ + if ( som->ndim!=2 ) return; + + char *fname; + FILE *fp = open_file(&fname,"w","%s.py",prefix); + fprintf(fp, + "import matplotlib as mpl\n" + "mpl.use('Agg')\n" + "import matplotlib.pyplot as plt\n" + "\n" + "dat = [\n" + ); + int i,j; + double *val = som->c; + for (i=0; inbin; i++) + { + fprintf(fp,"["); + for (j=0; jnbin; j++) + { + if ( j>0 ) fprintf(fp,","); + fprintf(fp,"%e", *val); + val++; + } + fprintf(fp,"],\n"); + } + fprintf(fp, + "]\n" + "fig = plt.figure()\n" + "ax1 = plt.subplot(111)\n" + "im1 = ax1.imshow(dat)\n" + "fig.colorbar(im1)\n" + "plt.savefig('%s.png')\n" + "plt.close()\n" + "\n", prefix + ); + fclose(fp); + free(fname); +} +// Find the best matching unit: the node with minimum distance from the input vector +static inline int som_find_bmu(som_t *som, double *vec, double *dist) +{ + double *ptr = som->w; + double min_dist = HUGE_VAL; + int min_idx = 0; + + int i, k; + for (i=0; isize; i++) + { + double dist = 0; + for (k=0; kkdim; k++) + dist += (vec[k] - ptr[k]) * (vec[k] - ptr[k]); + if ( dist < min_dist ) + { + min_dist = dist; + min_idx = i; + } + ptr += som->kdim; + } + + if ( dist ) *dist = min_dist; + return min_idx; +} +static inline double som_get_score(som_t *som, double *vec, double bmu_th) +{ + double *ptr = som->w; + double min_dist = HUGE_VAL; + + int i, k; + for (i=0; isize; i++) + { + if ( som->c[i] >= bmu_th ) + { + double dist = 0; + for (k=0; kkdim; k++) + dist += (vec[k] - ptr[k]) * (vec[k] - ptr[k]); + if ( dist < min_dist ) min_dist = dist; + } + ptr += som->kdim; + } + return sqrt(min_dist); +} +// Convert flat index to that of a k-dimensional cube +static inline void som_idx_to_ndim(som_t *som, int idx, int *ndim) +{ + int i; + double sub = 0; + + ndim[0] = idx/som->div[0]; + for (i=1; indim; i++) + { + sub += ndim[i-1] * som->div[i-1]; + ndim[i] = (idx - sub)/som->div[i]; + } +} +static void som_train_site(som_t *som, double *vec, int update_counts) +{ + // update learning rate and learning radius + som->t++; + double dt = exp(-som->t/som->nt); + double learning_rate = som->learn * dt; + double radius = som->nbin * dt; radius *= radius; + + // find the best matching unit and its indexes + int min_idx = som_find_bmu(som, vec, NULL); + som_idx_to_ndim(som, min_idx, som->a_idx); + + // update the weights: traverse the map and make all nodes within the + // radius more similar to the input vector + double *ptr = som->w; + double *cnt = som->c; + int i, j, k; + for (i=0; isize; i++) + { + som_idx_to_ndim(som, i, som->b_idx); + double dist = 0; + for (j=0; jndim; j++) + dist += (som->a_idx[j] - som->b_idx[j]) * (som->a_idx[j] - som->b_idx[j]); + if ( dist <= radius ) + { + double influence = exp(-dist*dist*0.5/radius) * learning_rate; + for (k=0; kkdim; k++) + ptr[k] += influence * (vec[k] - ptr[k]); + + // Bad sites may help to shape the map, but only nodes with big enough + // influence will be used for classification. + if ( update_counts ) *cnt += influence; + } + ptr += som->kdim; + cnt++; + } +} +static void som_norm_counts(som_t *som) +{ + int i; + double max = 0; + for (i=0; isize; i++) + if ( max < som->c[i] ) max = som->c[i]; + for (i=0; isize; i++) + som->c[i] /= max; +} +static som_t *som_init(args_t *args) +{ + som_t *som = (som_t*) calloc(1,sizeof(som_t)); + som->ndim = args->ndim; + som->nbin = args->nbin; + som->kdim = args->mvals; + som->nt = args->ntrain; + som->learn = args->learn; + som->bmu_th = args->bmu_th; + som->size = pow(som->nbin,som->ndim); + som->w = (double*) malloc(sizeof(double)*som->size*som->kdim); + if ( !som->w ) error("Could not alloc %d bytes [nbin=%d ndim=%d kdim=%d]\n", sizeof(double)*som->size*som->kdim,som->nbin,som->ndim,som->kdim); + som->c = (double*) calloc(som->size,sizeof(double)); + if ( !som->w ) error("Could not alloc %d bytes [nbin=%d ndim=%d]\n", sizeof(double)*som->size,som->nbin,som->ndim); + int i; + for (i=0; isize*som->kdim; i++) + som->w[i] = (double)random()/RAND_MAX; + som->a_idx = (int*) malloc(sizeof(int)*som->ndim); + som->b_idx = (int*) malloc(sizeof(int)*som->ndim); + som->div = (double*) malloc(sizeof(double)*som->ndim); + for (i=0; indim; i++) + som->div[i] = pow(som->nbin,som->ndim-i-1); + return som; +} +static void som_destroy(som_t *som) +{ + free(som->a_idx); free(som->b_idx); free(som->div); + free(som->w); free(som->c); + free(som); +} + +static void init_data(args_t *args) +{ + // Get first line to learn the vector size + annots_reader_reset(args); + annots_reader_next(args); + + if ( args->action==SOM_CLASSIFY ) + args->som = som_load_map(args->prefix,&args->nfold); +} +static void destroy_data(args_t *args) +{ + int i; + if ( args->som ) + { + for (i=0; infold; i++) som_destroy(args->som[i]); + } + free(args->train_dat); + free(args->train_class); + free(args->som); + free(args->vals); + free(args->str.s); +} + +#define MERGE_MIN 0 +#define MERGE_MAX 1 +#define MERGE_AVG 2 +static double get_min_score(args_t *args, int iskip) +{ + int i; + double score, min_score = HUGE_VAL; + for (i=0; infold; i++) + { + if ( i==iskip ) continue; + score = som_get_score(args->som[i], args->vals, args->bmu_th); + if ( i==0 || score < min_score ) min_score = score; + } + return min_score; +} +static double get_max_score(args_t *args, int iskip) +{ + int i; + double score, max_score = -HUGE_VAL; + for (i=0; infold; i++) + { + if ( i==iskip ) continue; + score = som_get_score(args->som[i], args->vals, args->bmu_th); + if ( i==0 || max_score < score ) max_score = score; + } + return max_score; +} +static double get_avg_score(args_t *args, int iskip) +{ + int i, n = 0; + double score = 0; + for (i=0; infold; i++) + { + if ( i==iskip ) continue; + score += som_get_score(args->som[i], args->vals, args->bmu_th); + n++; + } + return score/n; +} +static int cmpfloat_desc(const void *a, const void *b) +{ + float fa = *((float*)a); + float fb = *((float*)b); + if ( fafb ) return -1; + return 0; +} + +static void create_eval_plot(args_t *args) +{ + FILE *fp = open_file(NULL,"w","%s.eval.py", args->prefix); + fprintf(fp, + "import matplotlib as mpl\n" + "mpl.use('Agg')\n" + "import matplotlib.pyplot as plt\n" + "\n" + "import csv\n" + "csv.register_dialect('tab', delimiter='\\t', quoting=csv.QUOTE_NONE)\n" + "dat = []\n" + "with open('%s.eval', 'rb') as f:\n" + "\treader = csv.reader(f, 'tab')\n" + "\tfor row in reader:\n" + "\t\tif row[0][0]!='#': dat.append(row)\n" + "\n" + "fig = plt.figure()\n" + "ax1 = plt.subplot(111)\n" + "ax1.plot([x[0] for x in dat],[x[1] for x in dat],'g',label='Good')\n" + "ax1.plot([x[0] for x in dat],[x[2] for x in dat],'r',label='Bad')\n" + "ax1.set_xlabel('SOM score')\n" + "ax1.set_ylabel('Number of training sites')\n" + "ax1.legend(loc='best',prop={'size':8},frameon=False)\n" + "plt.savefig('%s.eval.png')\n" + "plt.close()\n" + "\n", args->prefix,args->prefix + ); + fclose(fp); +} + +static void do_train(args_t *args) +{ + // read training sites + int i, igood = 0, ibad = 0, ngood = 0, nbad = 0, ntrain = 0; + annots_reader_reset(args); + while ( annots_reader_next(args) ) + { + // determine which of the nfold's SOMs to train + int isom = 0; + if ( args->dclass == args->good_class ) + { + if ( ++igood >= args->nfold ) igood = 0; + isom = igood; + ngood++; + } + else if ( args->dclass == args->bad_class ) + { + if ( ++ibad >= args->nfold ) ibad = 0; + isom = ibad; + nbad++; + } + else + error("Could not determine the class: %d (vs %d and %d)\n", args->dclass,args->good_class,args->bad_class); + + // save the values for evaluation + ntrain++; + hts_expand(double, ntrain*args->mvals, args->mtrain_dat, args->train_dat); + hts_expand(int, ntrain, args->mtrain_class, args->train_class); + memcpy(args->train_dat+(ntrain-1)*args->mvals, args->vals, args->mvals*sizeof(double)); + args->train_class[ntrain-1] = (args->dclass==args->good_class ? 1 : 0) | isom<<1; // store class + chunk used for training + } + annots_reader_close(args); + + // init maps + if ( !args->ntrain ) args->ntrain = ngood/args->nfold; + srandom(args->rand_seed); + args->som = (som_t**) malloc(sizeof(som_t*)*args->nfold); + for (i=0; infold; i++) args->som[i] = som_init(args); + + // train + for (i=0; itrain_class[i] & 1; + int isom = args->train_class[i] >> 1; + if ( is_good || args->train_bad ) + som_train_site(args->som[isom], args->train_dat+i*args->mvals, is_good); + } + + // norm and create plots + for (i=0; infold; i++) + { + som_norm_counts(args->som[i]); + if ( args->prefix ) + { + char *bname = msprintf("%s.som.%d", args->prefix,i); + som_create_plot(args->som[i], bname); + free(bname); + } + } + + // evaluate + float *good = (float*) malloc(sizeof(float)*ngood); assert(good); + float *bad = (float*) malloc(sizeof(float)*nbad); assert(bad); + igood = ibad = 0; + double max_score = sqrt(args->som[0]->kdim); + for (i=0; itrain_class[i] & 1; + int isom = args->train_class[i] >> 1; // this vector was used for training isom-th SOM, skip + if ( args->nfold==1 ) isom = -1; + memcpy(args->vals, args->train_dat+i*args->mvals, args->mvals*sizeof(double)); + switch (args->merge) + { + case MERGE_MIN: score = get_min_score(args, isom); break; + case MERGE_MAX: score = get_max_score(args, isom); break; + case MERGE_AVG: score = get_avg_score(args, isom); break; + } + score = 1.0 - score/max_score; + if ( is_good ) + good[igood++] = score; + else + bad[ibad++] = score; + } + qsort(good, ngood, sizeof(float), cmpfloat_desc); + qsort(bad, nbad, sizeof(float), cmpfloat_desc); + FILE *fp = NULL; + if ( args->prefix ) fp = open_file(NULL,"w","%s.eval", args->prefix); + igood = 0; + ibad = 0; + float prev_score = good[0]>bad[0] ? good[0] : bad[0]; + int printed = 0; + while ( igood 0.9 ) + { + printf("%.2f\t%.2f\t%e\t# %% of bad [1] and good [2] sites at a cutoff [3]\n", 100.*ibad/nbad,100.*igood/ngood,prev_score); + printed = 1; + } + + if ( igoodbad[ibad] ? good[igood] : bad[ibad]; + else if ( igoodprefix,strerror(errno)); + create_eval_plot(args); + som_write_map(args->prefix, args->som, args->nfold); + } + + free(good); + free(bad); +} + +static void do_classify(args_t *args) +{ + annots_reader_reset(args); + double max_score = sqrt(args->som[0]->kdim); + while ( annots_reader_next(args) ) + { + double score = 0; + switch (args->merge) + { + case MERGE_MIN: score = get_min_score(args, -1); break; + case MERGE_MAX: score = get_max_score(args, -1); break; + case MERGE_AVG: score = get_avg_score(args, -1); break; + } + printf("%e\n", 1.0 - score/max_score); + } + annots_reader_close(args); +} + +static void usage(void) +{ + fprintf(stderr, "\n"); + fprintf(stderr, "About: SOM (Self-Organizing Map) filtering.\n"); + fprintf(stderr, "Usage: bcftools som --train [options] \n"); + fprintf(stderr, " bcftools som --classify [options]\n"); + fprintf(stderr, "\n"); + fprintf(stderr, "Model training options:\n"); + fprintf(stderr, " -f, --nfold n-fold cross-validation (number of maps) [5]\n"); + fprintf(stderr, " -p, --prefix prefix of output files\n"); + fprintf(stderr, " -s, --size map size [20]\n"); + fprintf(stderr, " -t, --train \n"); + fprintf(stderr, "\n"); + fprintf(stderr, "Classifying options:\n"); + fprintf(stderr, " -c, --classify \n"); + fprintf(stderr, "\n"); + fprintf(stderr, "Experimental training options (no reason to change):\n"); + fprintf(stderr, " -b, --bmu-threshold threshold for selection of best-matching unit [0.9]\n"); + fprintf(stderr, " -d, --som-dimension SOM dimension [2]\n"); + fprintf(stderr, " -e, --exclude-bad exclude bad sites from training, use for evaluation only\n"); + fprintf(stderr, " -l, --learning-rate learning rate [1.0]\n"); + fprintf(stderr, " -m, --merge -f merge algorithm [avg]\n"); + fprintf(stderr, " -n, --ntrain-sites effective number of training sites [number of good sites]\n"); + fprintf(stderr, " -r, --random-seed random seed, 0 for time() [1]\n"); + fprintf(stderr, "\n"); + exit(1); +} + +int main_vcfsom(int argc, char *argv[]) +{ + int c; + args_t *args = (args_t*) calloc(1,sizeof(args_t)); + args->argc = argc; args->argv = argv; + args->nbin = 20; + args->learn = 1.0; + args->bmu_th = 0.9; + args->nfold = 5; + args->rand_seed = 1; + args->ndim = 2; + args->bad_class = 1; + args->good_class = 2; + args->merge = MERGE_AVG; + args->train_bad = 1; + + static struct option loptions[] = + { + {"help",0,0,'h'}, + {"prefix",1,0,'p'}, + {"ntrain-sites",1,0,'n'}, + {"random-seed",1,0,'r'}, + {"bmu-threshold",1,0,'b'}, + {"exclude-bad",0,0,'e'}, + {"learning-rate",1,0,'l'}, + {"size",1,0,'s'}, + {"som-dimension",1,0,'d'}, + {"nfold",1,0,'f'}, + {"merge",1,0,'m'}, + {"train",0,0,'t'}, + {"classify",0,0,'c'}, + {0,0,0,0} + }; + while ((c = getopt_long(argc, argv, "htcp:n:r:b:l:s:f:d:m:e",loptions,NULL)) >= 0) { + switch (c) { + case 'e': args->train_bad = 0; break; + case 'm': + if ( !strcmp(optarg,"min") ) args->merge = MERGE_MIN; + else if ( !strcmp(optarg,"max") ) args->merge = MERGE_MAX; + else if ( !strcmp(optarg,"avg") ) args->merge = MERGE_AVG; + else error("The -m method not recognised: %s\n", optarg); + break; + case 'p': args->prefix = optarg; break; + case 'n': args->ntrain = atoi(optarg); break; + case 'r': args->rand_seed = atoi(optarg); break; + case 'b': args->bmu_th = atof(optarg); break; + case 'l': args->learn = atof(optarg); break; + case 's': args->nbin = atoi(optarg); break; + case 'f': args->nfold = atoi(optarg); break; + case 'd': + args->ndim = atoi(optarg); + if ( args->ndim<2 ) error("Expected -d >=2, got %d\n", args->ndim); + if ( args->ndim>3 ) fprintf(stderr,"Warning: This will take a long time and is not going to make the results better: -d %d\n", args->ndim); + break; + case 't': args->action = SOM_TRAIN; break; + case 'c': args->action = SOM_CLASSIFY; break; + case 'h': + case '?': usage(); + default: error("Unknown argument: %s\n", optarg); + } + } + + if ( !args->rand_seed ) args->rand_seed = time(NULL); + if ( argc!=optind+1 ) usage(); + args->fname = argv[optind]; + init_data(args); + + if ( args->action == SOM_TRAIN ) do_train(args); + else if ( args->action == SOM_CLASSIFY ) do_classify(args); + + destroy_data(args); + free(args); + return 0; +} + diff --git a/vcfstats.c b/vcfstats.c new file mode 100644 index 0000000..4041a5a --- /dev/null +++ b/vcfstats.c @@ -0,0 +1,1697 @@ +/* vcfstats.c -- Produces stats which can be plotted using plot-vcfstats. + + Copyright (C) 2012-2016 Genome Research Ltd. + + Author: Petr Danecek + +Permission is hereby granted, free of charge, to any person obtaining a copy +of this software and associated documentation files (the "Software"), to deal +in the Software without restriction, including without limitation the rights +to use, copy, modify, merge, publish, distribute, sublicense, and/or sell +copies of the Software, and to permit persons to whom the Software is +furnished to do so, subject to the following conditions: + +The above copyright notice and this permission notice shall be included in +all copies or substantial portions of the Software. + +THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE +AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER +LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, +OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN +THE SOFTWARE. */ + +/* + Notes and known issues: + - SN ts/tv calculation includes all non-ref alleles listed in ALT while per-sample ts/tv + takes the first non-ref allele only, something to consider with many non-ref HETs. +*/ +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include "bcftools.h" +#include "filter.h" +#include "bin.h" + +// Logic of the filters: include or exclude sites which match the filters? +#define FLT_INCLUDE 1 +#define FLT_EXCLUDE 2 + +#define HWE_STATS 1 +#define QUAL_STATS 1 +#define IRC_STATS 1 +#define IRC_RLEN 10 +#define NA_STRING "0" + +typedef struct +{ + char *tag; + float min, max; + uint64_t *vals_ts, *vals_tv; + void *val; + int nbins, type, m_val; +} +user_stats_t; + +typedef struct +{ + int min, max, step, m_vals; + uint64_t *vals; +} +idist_t; + +typedef struct +{ + int n_snps, n_indels, n_mnps, n_others, n_mals, n_snp_mals, n_records, n_noalts; + int *af_ts, *af_tv, *af_snps; // first bin of af_* stats are singletons + #if HWE_STATS + int *af_hwe; + #endif + #if IRC_STATS + int n_repeat[IRC_RLEN][4], n_repeat_na; // number of indels which are repeat-consistent, repeat-inconsistent (dels and ins), and not applicable + int *af_repeats[3]; + #endif + int ts_alt1, tv_alt1; + #if QUAL_STATS + int *qual_ts, *qual_tv, *qual_snps, *qual_indels; + #endif + int *insertions, *deletions, m_indel; // maximum indel length + int in_frame, out_frame, na_frame, in_frame_alt1, out_frame_alt1, na_frame_alt1; + int subst[15]; + int *smpl_hets, *smpl_homRR, *smpl_homAA, *smpl_ts, *smpl_tv, *smpl_indels, *smpl_ndp, *smpl_sngl; + int *smpl_indel_hets, *smpl_indel_homs; + int *smpl_frm_shifts; // not-applicable, in-frame, out-frame + unsigned long int *smpl_dp; + idist_t dp, dp_sites; + int nusr; + user_stats_t *usr; +} +stats_t; + +typedef struct +{ + uint64_t gt2gt[5][5]; // number of RR->RR, RR->RA, etc. matches/mismatches; see type2stats + /* + Pearson's R^2 is used for aggregate R^2 + y, yy .. sum of dosage and squared dosage in the query VCF (second file) + x, xx .. sum of squared dosage in the truth VCF (first file) + n .. number of genotypes + */ + double y, yy, x, xx, yx, n; +} +gtcmp_t; + +typedef struct +{ + char *seq; + int pos, cnt, len; +} +_idc1_t; +typedef struct +{ + faidx_t *ref; + _idc1_t *dat; + int ndat, mdat; +} +indel_ctx_t; + +typedef struct +{ + // stats + stats_t stats[3]; + int *tmp_iaf, ntmp_iaf, m_af, m_qual, naf_hwe, mtmp_frm; + uint8_t *tmp_frm; + int dp_min, dp_max, dp_step; + gtcmp_t *smpl_gts_snps, *smpl_gts_indels; + gtcmp_t *af_gts_snps, *af_gts_indels; // first bin of af_* stats are singletons + bin_t *af_bins; + float *farr; + int mfarr; + + // indel context + indel_ctx_t *indel_ctx; + char *ref_fname; + + // user stats + int nusr; + user_stats_t *usr; + + // other + bcf_srs_t *files; + bcf_sr_regions_t *exons; + char **argv, *exons_fname, *regions_list, *samples_list, *targets_list, *af_bins_list, *af_tag; + int argc, verbose_sites, first_allele_only, samples_is_file; + int split_by_id, nstats; + + filter_t *filter[2]; + char *filter_str; + int filter_logic; // include or exclude sites which match the filters? One of FLT_INCLUDE/FLT_EXCLUDE + int n_threads; +} +args_t; + +static int type2dosage[6], type2ploidy[6], type2stats[7]; + +static void idist_init(idist_t *d, int min, int max, int step) +{ + d->min = min; d->max = max; d->step = step; + d->m_vals = 4 + (d->max - d->min)/d->step; + d->vals = (uint64_t*) calloc(d->m_vals,sizeof(uint64_t)); +} +static void idist_destroy(idist_t *d) +{ + if ( d->vals ) free(d->vals); +} +static inline uint64_t *idist(idist_t *d, int val) +{ + if ( val < d->min ) return &d->vals[0]; + if ( val > d->max ) return &d->vals[d->m_vals-1]; + return &d->vals[1 + (val - d->min) / d->step]; +} +static inline int idist_i2bin(idist_t *d, int i) +{ + if ( i<=0 ) return d->min; + if ( i>= d->m_vals ) return d->max; + return i-1+d->min; +} + +static inline int clip_nonnegative(float x, int limit) +{ + if (x >= limit || isnan(x)) return limit - 1; + else if (x <= 0.0) return 0; + else return (int) x; +} + +#define IC_DBG 0 +#if IC_DBG +static void _indel_ctx_print1(_idc1_t *idc) +{ + int i; + fprintf(stdout, "%d\t", idc->cnt); + for (i=0; ilen; i++) + fputc(idc->seq[i], stdout); + fputc('\n', stdout); +} +static void _indel_ctx_print(indel_ctx_t *ctx) +{ + int i; + for (i=0; indat; i++) + _indel_ctx_print1(&ctx->dat[i]); + fputc('\n',stdout); +} +#endif +static int _indel_ctx_lookup(indel_ctx_t *ctx, char *seq, int seq_len, int *hit) +{ + // binary search + int min = 0, max = ctx->ndat - 1; + while ( min<=max ) + { + int i = (min+max)/2; + int cmp = strncmp(seq, ctx->dat[i].seq, seq_len); + if ( cmp<0 ) max = i - 1; + else if ( cmp>0 ) min = i + 1; + else + { + if ( seq_len==ctx->dat[i].len ) + { + *hit = 1; + return i; + } + else if ( seq_lendat[i].len ) max = i - 1; + else min = i + 1; + } + } + *hit = 0; + return max; +} +static void _indel_ctx_insert(indel_ctx_t *ctx, char *seq, int seq_len, int pos) +{ + int idat, hit, i; + idat = _indel_ctx_lookup(ctx, seq, seq_len, &hit); + if ( !hit ) + { + if ( pos>0 ) return; + idat++; + ctx->ndat++; + hts_expand(_idc1_t, ctx->ndat+1, ctx->mdat, ctx->dat); + if ( idatndat && ctx->ndat>1 ) + memmove(&ctx->dat[idat+1], &ctx->dat[idat], (ctx->ndat - idat - 1)*sizeof(_idc1_t)); + ctx->dat[idat].len = seq_len; + ctx->dat[idat].cnt = 1; + ctx->dat[idat].pos = pos; + ctx->dat[idat].seq = (char*) malloc(sizeof(char)*(seq_len+1)); + for (i=0; idat[idat].seq[i] = seq[i]; + ctx->dat[idat].seq[i] = 0; + return; + } + if ( ctx->dat[idat].pos + seq_len == pos ) + { + ctx->dat[idat].cnt++; + ctx->dat[idat].pos = pos; + } +} +indel_ctx_t *indel_ctx_init(char *fa_ref_fname) +{ + indel_ctx_t *ctx = (indel_ctx_t *) calloc(1,sizeof(indel_ctx_t)); + ctx->ref = fai_load(fa_ref_fname); + if ( !ctx->ref ) + { + free(ctx); + return NULL; + } + return ctx; +} +void indel_ctx_destroy(indel_ctx_t *ctx) +{ + fai_destroy(ctx->ref); + if ( ctx->mdat ) free(ctx->dat); + free(ctx); +} +/** + * indel_ctx_type() - determine indel context type + * @ctx: + * @chr: chromosome name + * @pos: position of the first @ref base, 1-based + * @ref: reference allele + * @alt: alternate allele. Only first of multiple comma-separated alleles is + * considered + * @nrep: number of repeated elements (w) + * @nlen: length of a single repeat element (w) + * + * Returns the INDEL length, negative for deletions, positive for insertions + */ +int indel_ctx_type(indel_ctx_t *ctx, char *chr, int pos, char *ref, char *alt, int *nrep, int *nlen) +{ + const int win_size = 50; // hard-wired for now + const int rep_len = IRC_RLEN; // hard-wired for now + + int ref_len = strlen(ref); + int alt_len = 0; + while ( alt[alt_len] && alt[alt_len]!=',' ) alt_len++; + + int i, fai_ref_len; + char *fai_ref = faidx_fetch_seq(ctx->ref, chr, pos-1, pos+win_size, &fai_ref_len); + for (i=0; i96 ) fai_ref[i] -= 32; + + // Sanity check: the reference sequence must match the REF allele + for (i=0; indat = 0; + for (i=0; indat; i++) + { + if ( max_cnt < ctx->dat[i].cnt || (max_cnt==ctx->dat[i].cnt && max_len < ctx->dat[i].len) ) + { + max_cnt = ctx->dat[i].cnt; + max_len = ctx->dat[i].len; + } + free(ctx->dat[i].seq); + } + free(fai_ref); + + *nrep = max_cnt; + *nlen = max_len; + return alt_len - ref_len; +} + +static void add_user_stats(args_t *args, char *str) +{ + args->nusr++; + args->usr = (user_stats_t*) realloc(args->usr,sizeof(user_stats_t)*args->nusr); + user_stats_t *usr = &args->usr[args->nusr-1]; + memset(usr,0,sizeof(*usr)); + usr->min = 0; + usr->max = 1; + usr->nbins = 100; + + char *tmp = str; + while ( *tmp && *tmp!=':' ) tmp++; + usr->tag = (char*)calloc(tmp-str+2,sizeof(char)); + memcpy(usr->tag,str,tmp-str); + + if ( *tmp ) + { + char *ptr = ++tmp; + usr->min = strtod(tmp, &ptr); + if ( tmp==ptr ) error("Could not parse %s\n", str); + tmp = ptr+1; + } + if ( *tmp ) + { + char *ptr = tmp; + usr->max = strtod(tmp, &ptr); + if ( tmp==ptr ) error("Could not parse %s\n", str); + tmp = ptr+1; + } + if ( *tmp ) + { + char *ptr = tmp; + usr->nbins = strtol(tmp, &ptr, 10); + if ( tmp==ptr ) error("Could not parse %s\n", str); + if ( usr->nbins<=0 ) error("Number of bins does not make sense (%d): %s.\n", usr->nbins, str); + } +} +static void init_user_stats(args_t *args, bcf_hdr_t *hdr, stats_t *stats) +{ + stats->nusr = args->nusr; + stats->usr = (user_stats_t*)malloc(sizeof(user_stats_t)*args->nusr); + memcpy(stats->usr,args->usr,args->nusr*sizeof(user_stats_t)); + int i; + for (i=0; inusr; i++) + { + user_stats_t *usr = &stats->usr[i]; + usr->vals_ts = (uint64_t*)calloc(usr->nbins,sizeof(uint64_t)); + usr->vals_tv = (uint64_t*)calloc(usr->nbins,sizeof(uint64_t)); + int id = bcf_hdr_id2int(hdr,BCF_DT_ID,usr->tag); + if ( !bcf_hdr_idinfo_exists(hdr,BCF_HL_INFO,id) ) error("The INFO tag \"%s\" is not defined in the header\n", usr->tag); + usr->type = bcf_hdr_id2type(hdr,BCF_HL_INFO,id); + if ( usr->type!=BCF_HT_REAL && usr->type!=BCF_HT_INT ) error("The INFO tag \"%s\" is not of Float or Integer type (%d)\n", usr->type); + } +} +static void init_stats(args_t *args) +{ + int i; + args->nstats = args->files->nreaders==1 ? 1 : 3; + if ( args->split_by_id ) args->nstats = 2; + + if ( args->filter_str ) + { + args->filter[0] = filter_init(bcf_sr_get_header(args->files,0), args->filter_str); + if ( args->files->nreaders==2 ) + args->filter[1] = filter_init(bcf_sr_get_header(args->files,1), args->filter_str); + args->files->max_unpack |= filter_max_unpack(args->filter[0]); + } + + // AF corresponds to AC but is more robust to mixtures of haploid and diploid GTs + if ( !args->af_bins_list ) + { + args->m_af = 101; + for (i=0; ifiles->nreaders; i++) + if ( bcf_hdr_nsamples(args->files->readers[i].header) + 1> args->m_af ) + args->m_af = bcf_hdr_nsamples(args->files->readers[i].header) + 1; + } + else + { + args->af_bins = bin_init(args->af_bins_list,0,1); + + // m_af is used also for other af arrays, where the first bin is for + // singletons. However, since the last element is unused in af_bins + // (n boundaries form n-1 intervals), the m_af count is good for both. + args->m_af = bin_get_size(args->af_bins); + } + + bcf_hdr_t *hdr = bcf_sr_get_header(args->files,0); + if ( args->af_tag && !bcf_hdr_idinfo_exists(hdr,BCF_HL_INFO,bcf_hdr_id2int(hdr,BCF_DT_ID,args->af_tag)) ) + error("No such INFO tag: %s\n", args->af_tag); + + #if QUAL_STATS + args->m_qual = 999; + #endif + #if HWE_STATS + args->naf_hwe = 100; + #endif + + if ( args->samples_list ) + { + if ( !bcf_sr_set_samples(args->files,args->samples_list,args->samples_is_file) ) + { + if ( !bcf_hdr_nsamples(args->files->readers[0].header) ) + error("No sample columns in %s\n", args->files->readers[0].fname); + error("Unable to parse the samples: \"%s\"\n", args->samples_list); + } + args->af_gts_snps = (gtcmp_t *) calloc(args->m_af,sizeof(gtcmp_t)); + args->af_gts_indels = (gtcmp_t *) calloc(args->m_af,sizeof(gtcmp_t)); + args->smpl_gts_snps = (gtcmp_t *) calloc(args->files->n_smpl,sizeof(gtcmp_t)); + args->smpl_gts_indels = (gtcmp_t *) calloc(args->files->n_smpl,sizeof(gtcmp_t)); + } + for (i=0; instats; i++) + { + stats_t *stats = &args->stats[i]; + stats->m_indel = 60; + stats->insertions = (int*) calloc(stats->m_indel,sizeof(int)); + stats->deletions = (int*) calloc(stats->m_indel,sizeof(int)); + stats->af_ts = (int*) calloc(args->m_af,sizeof(int)); + stats->af_tv = (int*) calloc(args->m_af,sizeof(int)); + stats->af_snps = (int*) calloc(args->m_af,sizeof(int)); + int j; + for (j=0; j<3; j++) stats->af_repeats[j] = (int*) calloc(args->m_af,sizeof(int)); + #if QUAL_STATS + stats->qual_ts = (int*) calloc(args->m_qual,sizeof(int)); + stats->qual_tv = (int*) calloc(args->m_qual,sizeof(int)); + stats->qual_snps = (int*) calloc(args->m_qual,sizeof(int)); + stats->qual_indels = (int*) calloc(args->m_qual,sizeof(int)); + #endif + if ( args->files->n_smpl ) + { + stats->smpl_hets = (int *) calloc(args->files->n_smpl,sizeof(int)); + stats->smpl_homAA = (int *) calloc(args->files->n_smpl,sizeof(int)); + stats->smpl_homRR = (int *) calloc(args->files->n_smpl,sizeof(int)); + stats->smpl_indel_hets = (int *) calloc(args->files->n_smpl,sizeof(int)); + stats->smpl_indel_homs = (int *) calloc(args->files->n_smpl,sizeof(int)); + stats->smpl_ts = (int *) calloc(args->files->n_smpl,sizeof(int)); + stats->smpl_tv = (int *) calloc(args->files->n_smpl,sizeof(int)); + stats->smpl_indels = (int *) calloc(args->files->n_smpl,sizeof(int)); + stats->smpl_dp = (unsigned long int *) calloc(args->files->n_smpl,sizeof(unsigned long int)); + stats->smpl_ndp = (int *) calloc(args->files->n_smpl,sizeof(int)); + stats->smpl_sngl = (int *) calloc(args->files->n_smpl,sizeof(int)); + #if HWE_STATS + stats->af_hwe = (int*) calloc(args->m_af*args->naf_hwe,sizeof(int)); + #endif + if ( args->exons_fname ) + stats->smpl_frm_shifts = (int*) calloc(args->files->n_smpl*3,sizeof(int)); + } + idist_init(&stats->dp, args->dp_min,args->dp_max,args->dp_step); + idist_init(&stats->dp_sites, args->dp_min,args->dp_max,args->dp_step); + init_user_stats(args, i!=1 ? args->files->readers[0].header : args->files->readers[1].header, stats); + } + + if ( args->exons_fname ) + { + args->exons = bcf_sr_regions_init(args->exons_fname,1,0,1,2); + if ( !args->exons ) + error("Error occurred while reading, was the file compressed with bgzip: %s?\n", args->exons_fname); + } + + #if IRC_STATS + if ( args->ref_fname ) + args->indel_ctx = indel_ctx_init(args->ref_fname); + #endif + + type2dosage[GT_HOM_RR] = 0; + type2dosage[GT_HET_RA] = 1; + type2dosage[GT_HOM_AA] = 2; + type2dosage[GT_HET_AA] = 2; + type2dosage[GT_HAPL_R] = 0; + type2dosage[GT_HAPL_A] = 1; + + type2ploidy[GT_HOM_RR] = 1; + type2ploidy[GT_HET_RA] = 1; + type2ploidy[GT_HOM_AA] = 1; + type2ploidy[GT_HET_AA] = 1; + type2ploidy[GT_HAPL_R] = -1; + type2ploidy[GT_HAPL_A] = -1; + + type2stats[GT_HOM_RR] = 0; + type2stats[GT_HET_RA] = 1; + type2stats[GT_HOM_AA] = 2; + type2stats[GT_HET_AA] = 3; + type2stats[GT_HAPL_R] = 0; + type2stats[GT_HAPL_A] = 2; + type2stats[GT_UNKN] = 4; + +} +static void destroy_stats(args_t *args) +{ + int id, j; + for (id=0; idnstats; id++) + { + stats_t *stats = &args->stats[id]; + if (stats->af_ts) free(stats->af_ts); + if (stats->af_tv) free(stats->af_tv); + if (stats->af_snps) free(stats->af_snps); + for (j=0; j<3; j++) + if (stats->af_repeats[j]) free(stats->af_repeats[j]); + #if QUAL_STATS + if (stats->qual_ts) free(stats->qual_ts); + if (stats->qual_tv) free(stats->qual_tv); + if (stats->qual_snps) free(stats->qual_snps); + if (stats->qual_indels) free(stats->qual_indels); + #endif + #if HWE_STATS + free(stats->af_hwe); + #endif + free(stats->insertions); + free(stats->deletions); + if (stats->smpl_hets) free(stats->smpl_hets); + if (stats->smpl_homAA) free(stats->smpl_homAA); + if (stats->smpl_homRR) free(stats->smpl_homRR); + if (stats->smpl_indel_homs) free(stats->smpl_indel_homs); + if (stats->smpl_indel_hets) free(stats->smpl_indel_hets); + if (stats->smpl_ts) free(stats->smpl_ts); + if (stats->smpl_tv) free(stats->smpl_tv); + if (stats->smpl_indels) free(stats->smpl_indels); + if (stats->smpl_dp) free(stats->smpl_dp); + if (stats->smpl_ndp) free(stats->smpl_ndp); + if (stats->smpl_sngl) free(stats->smpl_sngl); + idist_destroy(&stats->dp); + idist_destroy(&stats->dp_sites); + for (j=0; jnusr; j++) + { + free(stats->usr[j].vals_ts); + free(stats->usr[j].vals_tv); + free(stats->usr[j].val); + } + free(stats->usr); + if ( args->exons ) free(stats->smpl_frm_shifts); + } + for (j=0; jnusr; j++) free(args->usr[j].tag); + if ( args->af_bins ) bin_destroy(args->af_bins); + free(args->farr); + free(args->usr); + free(args->tmp_frm); + free(args->tmp_iaf); + if (args->exons) bcf_sr_regions_destroy(args->exons); + free(args->af_gts_snps); + free(args->af_gts_indels); + free(args->smpl_gts_snps); + free(args->smpl_gts_indels); + if (args->indel_ctx) indel_ctx_destroy(args->indel_ctx); + if (args->filter[0]) filter_destroy(args->filter[0]); + if (args->filter[1]) filter_destroy(args->filter[1]); +} + +static void init_iaf(args_t *args, bcf_sr_t *reader) +{ + bcf1_t *line = reader->buffer[0]; + hts_expand(int32_t,line->n_allele,args->ntmp_iaf,args->tmp_iaf); + + int i, ret; + if ( args->af_tag ) + { + ret = bcf_get_info_float(reader->header, line, args->af_tag, &args->farr, &args->mfarr); + if ( ret<=0 || ret!=line->n_allele-1 ) + { + // the AF tag is not present or wrong number of values, put in the singletons/unknown bin + for (i=0; in_allele; i++) args->tmp_iaf[i] = 0; + return; + } + args->tmp_iaf[0] = 0; + for (i=1; in_allele; i++) + { + float af = args->farr[i-1]; + if ( af<0 ) af = 0; + else if ( af>1 ) af = 1; + int iaf = args->af_bins ? bin_get_idx(args->af_bins,af) : af*(args->m_af-2); + args->tmp_iaf[i] = iaf + 1; // the first tmp_iaf bin is reserved for singletons + } + return; + } + + // tmp_iaf is first filled with AC counts in calc_ac and then transformed to + // an index to af_gts_snps + ret = bcf_calc_ac(reader->header, line, args->tmp_iaf, args->samples_list ? BCF_UN_INFO|BCF_UN_FMT : BCF_UN_INFO); + if ( !ret ) + { + for (i=0; in_allele; i++) args->tmp_iaf[i] = 0; // singletons/unknown bin + return; + } + + int an = 0; + for (i=0; in_allele; i++) + an += args->tmp_iaf[i]; + + args->tmp_iaf[0] = 0; + for (i=1; in_allele; i++) + { + if ( args->tmp_iaf[i]==1 ) + args->tmp_iaf[i] = 0; // singletons into the first bin + else if ( !an ) + args->tmp_iaf[i] = 1; // no genotype at all, put to the AF=0 bin + else + { + float af = (float) args->tmp_iaf[i] / an; + if ( af<0 ) af = 0; + else if ( af>1 ) af = 1; + int iaf = args->af_bins ? bin_get_idx(args->af_bins,af) : af*(args->m_af-2); + args->tmp_iaf[i] = iaf + 1; + } + } +} + +static inline void do_mnp_stats(args_t *args, stats_t *stats, bcf_sr_t *reader) +{ + stats->n_mnps++; +} + +static inline void do_other_stats(args_t *args, stats_t *stats, bcf_sr_t *reader) +{ + stats->n_others++; +} + +static void do_indel_stats(args_t *args, stats_t *stats, bcf_sr_t *reader) +{ + stats->n_indels++; + + bcf1_t *line = reader->buffer[0]; + + #if QUAL_STATS + int iqual = clip_nonnegative(line->qual, args->m_qual); + stats->qual_indels[iqual]++; + #endif + + // Check if the indel is near an exon for the frameshift statistics + int i, exon_overlap = 0; + if ( args->exons ) + { + if ( !bcf_sr_regions_overlap(args->exons, bcf_seqname(reader->header,line),line->pos,line->pos) ) exon_overlap = 1; + hts_expand(uint8_t,line->n_allele,args->mtmp_frm,args->tmp_frm); + for (i=0; in_allele; i++) args->tmp_frm[i] = 0; + } + + for (i=1; in_allele; i++) + { + if ( args->first_allele_only && i>1 ) break; + if ( bcf_get_variant_type(line,i)!=VCF_INDEL ) continue; + int len = line->d.var[i].n; + + #if IRC_STATS + // Indel repeat consistency + if ( args->indel_ctx ) + { + int nrep, nlen, ndel; + ndel = indel_ctx_type(args->indel_ctx, (char*)reader->header->id[BCF_DT_CTG][line->rid].key, line->pos+1, line->d.allele[0], line->d.allele[i], &nrep, &nlen); + if ( nlen<=1 || nrep<=1 ) + { + // not a repeat or a single base repeat + stats->n_repeat_na++; + stats->af_repeats[2][ args->tmp_iaf[i] ]++; + } + else + { + if ( abs(ndel) % nlen ) + { + // the length of the inserted/deleted sequence is not consistent with the repeat element + stats->n_repeat[nlen-1][ndel<0 ? 1 : 3]++; + stats->af_repeats[1][ args->tmp_iaf[i] ]++; + } + else + { + // the length consistent with the repeat + stats->n_repeat[nlen-1][ndel<0 ? 0 : 2]++; + stats->af_repeats[0][ args->tmp_iaf[i] ]++; + } + } + } + else + stats->af_repeats[2][ args->tmp_iaf[i] ]++; + #endif + + // Check the frameshifts + int tlen = 0; + if ( args->exons && exon_overlap ) // there is an exon + { + if ( len>0 ) + { + // insertion + if ( args->exons->start <= line->pos && args->exons->end > line->pos ) tlen = abs(len); + } + else if ( args->exons->start <= line->pos + abs(len) ) + { + // deletion + tlen = abs(len); + if ( line->pos < args->exons->start ) // trim the beginning + tlen -= args->exons->start - line->pos + 1; + if ( args->exons->end < line->pos + abs(len) ) // trim the end + tlen -= line->pos + abs(len) - args->exons->end; + } + } + if ( tlen ) // there are some deleted/inserted bases in the exon + { + if ( tlen%3 ) { stats->out_frame++; args->tmp_frm[i] = 2; } + else { stats->in_frame++; args->tmp_frm[i] = 1; } + + if ( i==1 ) + { + if ( tlen%3 ) stats->out_frame_alt1++; + else stats->in_frame_alt1++; + } + } + else // no exon affected + { + if ( i==1 ) stats->na_frame_alt1++; + stats->na_frame++; + } + + + // Indel length distribution + int *ptr = stats->insertions; + if ( len<0 ) + { + len *= -1; + ptr = stats->deletions; + } + if ( --len >= stats->m_indel ) len = stats->m_indel-1; + ptr[len]++; + } +} + +static void do_user_stats(stats_t *stats, bcf_sr_t *reader, int is_ts) +{ + int i; + for (i=0; inusr; i++) + { + user_stats_t *usr = &stats->usr[i]; + uint64_t *vals = is_ts ? usr->vals_ts : usr->vals_tv; + float val; + if ( usr->type==BCF_HT_REAL ) + { + if ( bcf_get_info_float(reader->header,reader->buffer[0],usr->tag,&usr->val,&usr->m_val)<=0 ) continue; + val = ((float*)usr->val)[0]; + } + else + { + if ( bcf_get_info_int32(reader->header,reader->buffer[0],usr->tag,&usr->val,&usr->m_val)<=0 ) continue; + val = ((int32_t*)usr->val)[0]; + } + int idx; + if ( val<=usr->min ) idx = 0; + else if ( val>=usr->max ) idx = usr->nbins - 1; + else idx = (val - usr->min)/(usr->max - usr->min) * (usr->nbins-1); + vals[idx]++; + } +} + +static void do_snp_stats(args_t *args, stats_t *stats, bcf_sr_t *reader) +{ + stats->n_snps++; + + bcf1_t *line = reader->buffer[0]; + int ref = bcf_acgt2int(*line->d.allele[0]); + if ( ref<0 ) return; + + #if QUAL_STATS + int iqual = clip_nonnegative(line->qual, args->m_qual); + stats->qual_snps[iqual]++; + #endif + + int i; + for (i=1; in_allele; i++) + { + if ( args->first_allele_only && i>1 ) break; + if ( !(bcf_get_variant_type(line,i)&VCF_SNP) ) continue; + int alt = bcf_acgt2int(*line->d.allele[i]); + if ( alt<0 || ref==alt ) continue; + stats->subst[ref<<2|alt]++; + int iaf = args->tmp_iaf[i]; + stats->af_snps[iaf]++; + if ( abs(ref-alt)==2 ) + { + if (i==1) + { + stats->ts_alt1++; + #if QUAL_STATS + stats->qual_ts[iqual]++; + #endif + do_user_stats(stats, reader, 1); + } + stats->af_ts[iaf]++; + } + else + { + if (i==1) + { + stats->tv_alt1++; + #if QUAL_STATS + stats->qual_tv[iqual]++; + #endif + do_user_stats(stats, reader, 0); + } + stats->af_tv[iaf]++; + } + } +} + +static void do_sample_stats(args_t *args, stats_t *stats, bcf_sr_t *reader, int matched) +{ + bcf_srs_t *files = args->files; + bcf1_t *line = reader->buffer[0]; + bcf_fmt_t *fmt_ptr; + int nref_tot = 0, nhet_tot = 0, nalt_tot = 0; + int line_type = bcf_get_variant_types(line); + + if ( (fmt_ptr = bcf_get_fmt(reader->header,reader->buffer[0],"GT")) ) + { + int ref = bcf_acgt2int(*line->d.allele[0]); + int is, n_nref = 0, i_nref = 0; + for (is=0; isfiles->n_smpl; is++) + { + int ial, jal; + int gt = bcf_gt_type(fmt_ptr, reader->samples[is], &ial, &jal); + if ( gt==GT_UNKN ) continue; + if ( gt==GT_HAPL_R || gt==GT_HAPL_A ) + { + if ( line_type&VCF_INDEL && stats->smpl_frm_shifts ) + { + assert( ialn_allele ); + stats->smpl_frm_shifts[is*3 + args->tmp_frm[ial]]++; + } + continue; + } + if ( gt != GT_HOM_RR ) { n_nref++; i_nref = is; } + #if HWE_STATS + switch (gt) + { + case GT_HOM_RR: nref_tot++; break; + case GT_HET_RA: nhet_tot++; break; + case GT_HET_AA: + case GT_HOM_AA: nalt_tot++; break; + } + #endif + if ( line_type&VCF_SNP || line_type==VCF_REF ) // count ALT=. as SNP + { + if ( gt == GT_HET_RA ) stats->smpl_hets[is]++; + else if ( gt == GT_HET_AA ) stats->smpl_hets[is]++; + else if ( gt == GT_HOM_RR ) stats->smpl_homRR[is]++; + else if ( gt == GT_HOM_AA ) stats->smpl_homAA[is]++; + if ( gt != GT_HOM_RR && line->d.var[ial].type&VCF_SNP ) // this is safe, bcf_get_variant_types has been already called + { + int alt = bcf_acgt2int(*line->d.allele[ial]); + if ( alt<0 ) continue; + if ( abs(ref-alt)==2 ) + stats->smpl_ts[is]++; + else + stats->smpl_tv[is]++; + } + } + if ( line_type&VCF_INDEL ) + { + if ( gt != GT_HOM_RR ) + { + stats->smpl_indels[is]++; + if ( gt==GT_HET_RA || gt==GT_HET_AA ) stats->smpl_indel_hets[is]++; + else if ( gt==GT_HOM_AA ) stats->smpl_indel_homs[is]++; + } + if ( stats->smpl_frm_shifts ) + { + assert( ialn_allele && jaln_allele ); + stats->smpl_frm_shifts[is*3 + args->tmp_frm[ial]]++; + stats->smpl_frm_shifts[is*3 + args->tmp_frm[jal]]++; + } + } + } + if ( n_nref==1 ) stats->smpl_sngl[i_nref]++; + } + + #if HWE_STATS + if ( nhet_tot + nref_tot + nalt_tot ) + { + float het_frac = (float)nhet_tot/(nhet_tot + nref_tot + nalt_tot); + int idx = het_frac*(args->naf_hwe - 1); +//check me: what is this? + if ( line->n_allele>1 ) idx += args->naf_hwe*args->tmp_iaf[1]; + stats->af_hwe[idx]++; + } + #endif + + if ( (fmt_ptr = bcf_get_fmt(reader->header,reader->buffer[0],"DP")) ) + { + #define BRANCH_INT(type_t,missing,vector_end) { \ + int is; \ + for (is=0; isfiles->n_smpl; is++) \ + { \ + type_t *p = (type_t *) (fmt_ptr->p + fmt_ptr->size*is); \ + if ( *p==vector_end ) continue; \ + if ( *p!=missing ) \ + { \ + (*idist(&stats->dp, *p))++; \ + stats->smpl_ndp[is]++; \ + stats->smpl_dp[is] += *p; \ + } \ + } \ + } + switch (fmt_ptr->type) { + case BCF_BT_INT8: BRANCH_INT(int8_t, bcf_int8_missing, bcf_int8_vector_end); break; + case BCF_BT_INT16: BRANCH_INT(int16_t, bcf_int16_missing, bcf_int16_vector_end); break; + case BCF_BT_INT32: BRANCH_INT(int32_t, bcf_int32_missing, bcf_int32_vector_end); break; + default: fprintf(stderr, "[E::%s] todo: %d\n", __func__, fmt_ptr->type); exit(1); break; + } + #undef BRANCH_INT + } + + if ( matched==3 ) + { + int is; + bcf_fmt_t *fmt0, *fmt1; + fmt0 = bcf_get_fmt(files->readers[0].header,files->readers[0].buffer[0],"GT"); if ( !fmt0 ) return; + fmt1 = bcf_get_fmt(files->readers[1].header,files->readers[1].buffer[0],"GT"); if ( !fmt1 ) return; + + // only the first ALT allele is considered + int iaf = args->tmp_iaf[1]; + int line_type = bcf_get_variant_types(files->readers[0].buffer[0]); + gtcmp_t *af_stats = line_type&VCF_SNP ? args->af_gts_snps : args->af_gts_indels; + gtcmp_t *smpl_stats = line_type&VCF_SNP ? args->smpl_gts_snps : args->smpl_gts_indels; + + for (is=0; isn_smpl; is++) + { + // Simplified comparison: only 0/0, 0/1, 1/1 is looked at as the identity of + // actual alleles can be enforced by running without the -c option. + int gt0 = bcf_gt_type(fmt0, files->readers[0].samples[is], NULL, NULL); + int gt1 = bcf_gt_type(fmt1, files->readers[1].samples[is], NULL, NULL); + + int idx0 = type2stats[gt0]; + int idx1 = type2stats[gt1]; + af_stats[iaf].gt2gt[idx0][idx1]++; + smpl_stats[is].gt2gt[idx0][idx1]++; + + if ( gt0 == GT_UNKN || gt1 == GT_UNKN ) continue; + if ( type2ploidy[gt0]*type2ploidy[gt1] == -1 ) continue; // cannot compare diploid and haploid genotypes + + float y = type2dosage[gt0]; + float x = type2dosage[gt1]; + + smpl_stats[is].yx += y*x; + smpl_stats[is].x += x; + smpl_stats[is].xx += x*x; + smpl_stats[is].y += y; + smpl_stats[is].yy += y*y; + smpl_stats[is].n += 1; + + af_stats[iaf].yx += y*x; + af_stats[iaf].x += x; + af_stats[iaf].xx += x*x; + af_stats[iaf].y += y; + af_stats[iaf].yy += y*y; + af_stats[iaf].n += 1; + } + + if ( args->verbose_sites ) + { + int nm = 0, nmm = 0, nrefm = 0; + for (is=0; isn_smpl; is++) + { + int gt = bcf_gt_type(fmt0, files->readers[0].samples[is], NULL, NULL); + if ( gt == GT_UNKN ) continue; + int gt2 = bcf_gt_type(fmt1, files->readers[1].samples[is], NULL, NULL); + if ( gt2 == GT_UNKN ) continue; + if ( gt != gt2 ) + { + nmm++; + bcf_sr_t *reader = &files->readers[0]; + printf("DBG\t%s\t%d\t%s\t%d\t%d\n",reader->header->id[BCF_DT_CTG][reader->buffer[0]->rid].key,reader->buffer[0]->pos+1,files->samples[is],gt,gt2); + } + else + { + if ( gt!=GT_HOM_RR ) nrefm++; + nm++; + } + } + float nrd = nrefm+nmm ? 100.*nmm/(nrefm+nmm) : 0; + printf("PSD\t%s\t%d\t%d\t%d\t%f\n", reader->header->id[BCF_DT_CTG][reader->buffer[0]->rid].key,reader->buffer[0]->pos+1,nm,nmm,nrd); + } + } +} + +static void do_vcf_stats(args_t *args) +{ + bcf_srs_t *files = args->files; + assert( sizeof(int)>files->nreaders ); + while ( bcf_sr_next_line(files) ) + { + bcf_sr_t *reader = NULL; + bcf1_t *line = NULL; + int ret = 0, i, pass = 1; + for (i=0; inreaders; i++) + { + if ( !bcf_sr_has_line(files,i) ) continue; + if ( args->filter[i] ) + { + int is_ok = filter_test(args->filter[i], bcf_sr_get_line(files,i), NULL); + if ( args->filter_logic & FLT_EXCLUDE ) is_ok = is_ok ? 0 : 1; + if ( !is_ok ) { pass = 0; break; } + } + ret |= 1<readers[i]; + line = bcf_sr_get_line(files,i); + } + + } + if ( !pass ) continue; + + int line_type = bcf_get_variant_types(line); + init_iaf(args, reader); + + stats_t *stats = &args->stats[ret-1]; + if ( args->split_by_id && line->d.id[0]=='.' && !line->d.id[1] ) + stats = &args->stats[1]; + + stats->n_records++; + + if ( line_type==VCF_REF ) + stats->n_noalts++; + if ( line_type&VCF_SNP ) + do_snp_stats(args, stats, reader); + if ( line_type&VCF_INDEL ) + do_indel_stats(args, stats, reader); + if ( line_type&VCF_MNP ) + do_mnp_stats(args, stats, reader); + if ( line_type&VCF_OTHER ) + do_other_stats(args, stats, reader); + + if ( line->n_allele>2 ) + { + stats->n_mals++; + if ( line_type == VCF_SNP ) stats->n_snp_mals++; + } + + if ( files->n_smpl ) + do_sample_stats(args, stats, reader, ret); + + if ( bcf_get_info_int32(reader->header,line,"DP",&args->tmp_iaf,&args->ntmp_iaf)==1 ) + (*idist(&stats->dp_sites, args->tmp_iaf[0]))++; + } +} + +static void print_header(args_t *args) +{ + int i; + printf("# This file was produced by bcftools stats (%s+htslib-%s) and can be plotted using plot-vcfstats.\n", bcftools_version(),hts_version()); + printf("# The command line was:\tbcftools %s ", args->argv[0]); + for (i=1; iargc; i++) + printf(" %s",args->argv[i]); + printf("\n#\n"); + + printf("# Definition of sets:\n# ID\t[2]id\t[3]tab-separated file names\n"); + if ( args->files->nreaders==1 ) + { + const char *fname = strcmp("-",args->files->readers[0].fname) ? args->files->readers[0].fname : ""; + if ( args->split_by_id ) + { + printf("ID\t0\t%s:known (sites with ID different from \".\")\n", fname); + printf("ID\t1\t%s:novel (sites where ID column is \".\")\n", fname); + } + else + printf("ID\t0\t%s\n", fname); + } + else + { + const char *fname0 = strcmp("-",args->files->readers[0].fname) ? args->files->readers[0].fname : ""; + const char *fname1 = strcmp("-",args->files->readers[1].fname) ? args->files->readers[1].fname : ""; + printf("ID\t0\t%s\n", fname0); + printf("ID\t1\t%s\n", fname1); + printf("ID\t2\t%s\t%s\n", fname0,fname1); + + if ( args->verbose_sites ) + { + printf( + "# Verbose per-site discordance output.\n" + "# PSD\t[2]CHROM\t[3]POS\t[4]Number of matches\t[5]Number of mismatches\t[6]NRD\n"); + printf( + "# Verbose per-site and per-sample output. Genotype codes: %d:HomRefRef, %d:HomAltAlt, %d:HetAltRef, %d:HetAltAlt, %d:haploidRef, %d:haploidAlt\n" + "# DBG\t[2]CHROM\t[3]POS\t[4]Sample\t[5]GT in %s\t[6]GT in %s\n", + GT_HOM_RR, GT_HOM_AA, GT_HET_RA, GT_HET_AA, GT_HAPL_R, GT_HAPL_A, fname0,fname1); + } + } +} + +#define T2S(x) type2stats[x] +static void print_stats(args_t *args) +{ + int i, j,k, id; + printf("# SN, Summary numbers:\n# SN\t[2]id\t[3]key\t[4]value\n"); + for (id=0; idfiles->nreaders; id++) + printf("SN\t%d\tnumber of samples:\t%d\n", id, bcf_hdr_nsamples(args->files->readers[id].header)); + for (id=0; idnstats; id++) + { + stats_t *stats = &args->stats[id]; + printf("SN\t%d\tnumber of records:\t%d\n", id, stats->n_records); + printf("SN\t%d\tnumber of no-ALTs:\t%d\n", id, stats->n_noalts); + printf("SN\t%d\tnumber of SNPs:\t%d\n", id, stats->n_snps); + printf("SN\t%d\tnumber of MNPs:\t%d\n", id, stats->n_mnps); + printf("SN\t%d\tnumber of indels:\t%d\n", id, stats->n_indels); + printf("SN\t%d\tnumber of others:\t%d\n", id, stats->n_others); + printf("SN\t%d\tnumber of multiallelic sites:\t%d\n", id, stats->n_mals); + printf("SN\t%d\tnumber of multiallelic SNP sites:\t%d\n", id, stats->n_snp_mals); + } + printf("# TSTV, transitions/transversions:\n# TSTV\t[2]id\t[3]ts\t[4]tv\t[5]ts/tv\t[6]ts (1st ALT)\t[7]tv (1st ALT)\t[8]ts/tv (1st ALT)\n"); + for (id=0; idnstats; id++) + { + stats_t *stats = &args->stats[id]; + int ts=0,tv=0; + for (i=0; im_af; i++) { ts += stats->af_ts[i]; tv += stats->af_tv[i]; } + printf("TSTV\t%d\t%d\t%d\t%.2f\t%d\t%d\t%.2f\n", id,ts,tv,tv?(float)ts/tv:0, stats->ts_alt1,stats->tv_alt1,stats->tv_alt1?(float)stats->ts_alt1/stats->tv_alt1:0); + } + if ( args->exons_fname ) + { + printf("# FS, Indel frameshifts:\n# FS\t[2]id\t[3]in-frame\t[4]out-frame\t[5]not applicable\t[6]out/(in+out) ratio\t[7]in-frame (1st ALT)\t[8]out-frame (1st ALT)\t[9]not applicable (1st ALT)\t[10]out/(in+out) ratio (1st ALT)\n"); + for (id=0; idnstats; id++) + { + int in=args->stats[id].in_frame, out=args->stats[id].out_frame, na=args->stats[id].na_frame; + int in1=args->stats[id].in_frame_alt1, out1=args->stats[id].out_frame_alt1, na1=args->stats[id].na_frame_alt1; + printf("FS\t%d\t%d\t%d\t%d\t%.2f\t%d\t%d\t%d\t%.2f\n", id, in,out,na,out?(float)out/(in+out):0,in1,out1,na1,out1?(float)out1/(in1+out1):0); + } + } + if ( args->indel_ctx ) + { + printf("# ICS, Indel context summary:\n# ICS\t[2]id\t[3]repeat-consistent\t[4]repeat-inconsistent\t[5]not applicable\t[6]c/(c+i) ratio\n"); + for (id=0; idnstats; id++) + { + int nc = 0, ni = 0, na = args->stats[id].n_repeat_na; + for (i=0; istats[id].n_repeat[i][0] + args->stats[id].n_repeat[i][2]; + ni += args->stats[id].n_repeat[i][1] + args->stats[id].n_repeat[i][3]; + } + printf("ICS\t%d\t%d\t%d\t%d\t%.4f\n", id, nc,ni,na,nc+ni ? (float)nc/(nc+ni) : 0.0); + } + printf("# ICL, Indel context by length:\n# ICL\t[2]id\t[3]length of repeat element\t[4]repeat-consistent deletions)\t[5]repeat-inconsistent deletions\t[6]consistent insertions\t[7]inconsistent insertions\t[8]c/(c+i) ratio\n"); + for (id=0; idnstats; id++) + { + for (i=1; istats[id].n_repeat[i][0]+args->stats[id].n_repeat[i][2], ni = args->stats[id].n_repeat[i][1]+args->stats[id].n_repeat[i][3]; + printf("ICL\t%d\t%d\t%d\t%d\t%d\t%d\t%.4f\n", id, i+1, + args->stats[id].n_repeat[i][0],args->stats[id].n_repeat[i][1],args->stats[id].n_repeat[i][2],args->stats[id].n_repeat[i][3], + nc+ni ? (float)nc/(nc+ni) : 0.0); + } + } + } + printf("# SiS, Singleton stats:\n# SiS\t[2]id\t[3]allele count\t[4]number of SNPs\t[5]number of transitions\t[6]number of transversions\t[7]number of indels\t[8]repeat-consistent\t[9]repeat-inconsistent\t[10]not applicable\n"); + for (id=0; idnstats; id++) + { + stats_t *stats = &args->stats[id]; + printf("SiS\t%d\t%d\t%d\t%d\t%d\t%d\t%d\t%d\t%d\n", id,1,stats->af_snps[0],stats->af_ts[0],stats->af_tv[0], + stats->af_repeats[0][0]+stats->af_repeats[1][0]+stats->af_repeats[2][0],stats->af_repeats[0][0],stats->af_repeats[1][0],stats->af_repeats[2][0]); + // put the singletons stats into the first AF bin, note that not all of the stats is transferred (i.e. nrd mismatches) + stats->af_snps[1] += stats->af_snps[0]; + stats->af_ts[1] += stats->af_ts[0]; + stats->af_tv[1] += stats->af_tv[0]; + stats->af_repeats[0][1] += stats->af_repeats[0][0]; + stats->af_repeats[1][1] += stats->af_repeats[1][0]; + stats->af_repeats[2][1] += stats->af_repeats[2][0]; + } + // move the singletons stats into the first AF bin, singleton stats was collected separately because of init_iaf + if ( args->af_gts_snps ) + { + args->af_gts_snps[1].y += args->af_gts_snps[0].y; + args->af_gts_snps[1].yy += args->af_gts_snps[0].yy; + args->af_gts_snps[1].xx += args->af_gts_snps[0].xx; + args->af_gts_snps[1].yx += args->af_gts_snps[0].yx; + args->af_gts_snps[1].n += args->af_gts_snps[0].n; + } + if ( args->af_gts_indels ) + { + args->af_gts_indels[1].y += args->af_gts_indels[0].y; + args->af_gts_indels[1].yy += args->af_gts_indels[0].yy; + args->af_gts_indels[1].xx += args->af_gts_indels[0].xx; + args->af_gts_indels[1].yx += args->af_gts_indels[0].yx; + args->af_gts_indels[1].n += args->af_gts_indels[0].n; + } + + printf("# AF, Stats by non-reference allele frequency:\n# AF\t[2]id\t[3]allele frequency\t[4]number of SNPs\t[5]number of transitions\t[6]number of transversions\t[7]number of indels\t[8]repeat-consistent\t[9]repeat-inconsistent\t[10]not applicable\n"); + for (id=0; idnstats; id++) + { + stats_t *stats = &args->stats[id]; + for (i=1; im_af; i++) // note that af[1] now contains also af[0], see SiS stats output above + { + if ( stats->af_snps[i]+stats->af_ts[i]+stats->af_tv[i]+stats->af_repeats[0][i]+stats->af_repeats[1][i]+stats->af_repeats[2][i] == 0 ) continue; + double af = args->af_bins ? (bin_get_value(args->af_bins,i)+bin_get_value(args->af_bins,i-1))*0.5 : (double)(i-1)/(args->m_af-1); + printf("AF\t%d\t%f\t%d\t%d\t%d\t%d\t%d\t%d\t%d\n", id,af,stats->af_snps[i],stats->af_ts[i],stats->af_tv[i], + stats->af_repeats[0][i]+stats->af_repeats[1][i]+stats->af_repeats[2][i],stats->af_repeats[0][i],stats->af_repeats[1][i],stats->af_repeats[2][i]); + } + } + #if QUAL_STATS + printf("# QUAL, Stats by quality:\n# QUAL\t[2]id\t[3]Quality\t[4]number of SNPs\t[5]number of transitions (1st ALT)\t[6]number of transversions (1st ALT)\t[7]number of indels\n"); + for (id=0; idnstats; id++) + { + stats_t *stats = &args->stats[id]; + for (i=0; im_qual; i++) + { + if ( stats->qual_snps[i]+stats->qual_ts[i]+stats->qual_tv[i]+stats->qual_indels[i] == 0 ) continue; + printf("QUAL\t%d\t%d\t%d\t%d\t%d\t%d\n", id,i,stats->qual_snps[i],stats->qual_ts[i],stats->qual_tv[i],stats->qual_indels[i]); + } + } + #endif + for (i=0; inusr; i++) + { + printf("# USR:%s, Stats by %s:\n# USR:%s\t[2]id\t[3]%s\t[4]number of SNPs\t[5]number of transitions (1st ALT)\t[6]number of transversions (1st ALT)\n", + args->usr[i].tag,args->usr[i].tag,args->usr[i].tag,args->usr[i].tag); + for (id=0; idnstats; id++) + { + user_stats_t *usr = &args->stats[id].usr[i]; + int j; + for (j=0; jnbins; j++) + { + if ( usr->vals_ts[j]+usr->vals_tv[j] == 0 ) continue; // skip empty bins + float val = usr->min + (usr->max - usr->min)*j/(usr->nbins-1); + const char *fmt = usr->type==BCF_HT_REAL ? "USR:%s\t%d\t%e\t%d\t%d\t%d\n" : "USR:%s\t%d\t%.0f\t%d\t%d\t%d\n"; + printf(fmt,usr->tag,id,val,usr->vals_ts[j]+usr->vals_tv[j],usr->vals_ts[j],usr->vals_tv[j]); + } + } + } + printf("# IDD, InDel distribution:\n# IDD\t[2]id\t[3]length (deletions negative)\t[4]count\n"); + for (id=0; idnstats; id++) + { + stats_t *stats = &args->stats[id]; + for (i=stats->m_indel-1; i>=0; i--) + if ( stats->deletions[i] ) printf("IDD\t%d\t%d\t%d\n", id,-i-1,stats->deletions[i]); + for (i=0; im_indel; i++) + if ( stats->insertions[i] ) printf("IDD\t%d\t%d\t%d\n", id,i+1,stats->insertions[i]); + } + printf("# ST, Substitution types:\n# ST\t[2]id\t[3]type\t[4]count\n"); + for (id=0; idnstats; id++) + { + int t; + for (t=0; t<15; t++) + { + if ( t>>2 == (t&3) ) continue; + printf("ST\t%d\t%c>%c\t%d\n", id, bcf_int2acgt(t>>2),bcf_int2acgt(t&3),args->stats[id].subst[t]); + } + } + if ( args->files->nreaders>1 && args->files->n_smpl ) + { + printf("SN\t%d\tnumber of samples:\t%d\n", 2, args->files->n_smpl); + + int x; + for (x=0; x<2; x++) // x=0: snps, x=1: indels + { + gtcmp_t *stats; + if ( x==0 ) + { + printf("# GCsAF, Genotype concordance by non-reference allele frequency (SNPs)\n# GCsAF\t[2]id\t[3]allele frequency\t[4]RR Hom matches\t[5]RA Het matches\t[6]AA Hom matches\t[7]RR Hom mismatches\t[8]RA Het mismatches\t[9]AA Hom mismatches\t[10]dosage r-squared\t[11]number of genotypes\n"); + stats = args->af_gts_snps; + } + else + { + printf("# GCiAF, Genotype concordance by non-reference allele frequency (indels)\n# GCiAF\t[2]id\t[3]allele frequency\t[4]RR Hom matches\t[5]RA Het matches\t[6]AA Hom matches\t[7]RR Hom mismatches\t[8]RA Het mismatches\t[9]AA Hom mismatches\t[10]dosage r-squared\t[11]number of genotypes\n"); + stats = args->af_gts_indels; + } + uint64_t nrd_m[4] = {0,0,0,0}, nrd_mm[4] = {0,0,0,0}; // across all bins + for (i=0; im_af; i++) + { + int n = 0; + uint64_t m[4] = {0,0,0,0}, mm[4] = {0,0,0,0}; // in i-th AF bin + for (j=0; j<4; j++) // rr, ra, aa hom, aa het, ./. + for (k=0; k<4; k++) + { + n += stats[i].gt2gt[j][k]; + if ( j==k ) + { + nrd_m[j] += stats[i].gt2gt[j][k]; + m[j] += stats[i].gt2gt[j][k]; + } + else + { + nrd_mm[j] += stats[i].gt2gt[j][k]; + mm[j] += stats[i].gt2gt[j][k]; + } + } + if ( !i || !n ) continue; // skip singleton stats and empty bins + + // Pearson's r2 + double r2 = 0; + if ( stats[i].n ) + { + r2 = (stats[i].yx - stats[i].x*stats[i].y/stats[i].n); + r2 /= sqrt((stats[i].xx - stats[i].x*stats[i].x/stats[i].n) * (stats[i].yy - stats[i].y*stats[i].y/stats[i].n)); + r2 *= r2; + } + double af = args->af_bins ? (bin_get_value(args->af_bins,i)+bin_get_value(args->af_bins,i-1))*0.5 : (double)(i-1)/(args->m_af-1); + printf("GC%cAF\t2\t%f", x==0 ? 's' : 'i', af); + printf("\t%"PRId64"\t%"PRId64"\t%"PRId64"", m[T2S(GT_HOM_RR)],m[T2S(GT_HET_RA)],m[T2S(GT_HOM_AA)]); + printf("\t%"PRId64"\t%"PRId64"\t%"PRId64"", mm[T2S(GT_HOM_RR)],mm[T2S(GT_HET_RA)],mm[T2S(GT_HOM_AA)]); + if ( stats[i].n && !isnan(r2) ) printf("\t%f", r2); + else printf("\t"NA_STRING); + printf("\t%.0f\n", stats[i].n); + } + + if ( x==0 ) + { + printf("# NRD and discordance is calculated as follows:\n"); + printf("# m .. number of matches\n"); + printf("# x .. number of mismatches\n"); + printf("# NRD = (xRR + xRA + xAA) / (xRR + xRA + xAA + mRA + mAA)\n"); + printf("# RR discordance = xRR / (xRR + mRR)\n"); + printf("# RA discordance = xRA / (xRA + mRA)\n"); + printf("# AA discordance = xAA / (xAA + mAA)\n"); + printf("# Non-Reference Discordance (NRD), SNPs\n# NRDs\t[2]id\t[3]NRD\t[4]Ref/Ref discordance\t[5]Ref/Alt discordance\t[6]Alt/Alt discordance\n"); + } + else + printf("# Non-Reference Discordance (NRD), indels\n# NRDi\t[2]id\t[3]NRD\t[4]Ref/Ref discordance\t[5]Ref/Alt discordance\t[6]Alt/Alt discordance\n"); + uint64_t m = nrd_m[T2S(GT_HET_RA)] + nrd_m[T2S(GT_HOM_AA)] + nrd_m[T2S(GT_HET_AA)]; + uint64_t mm = nrd_mm[T2S(GT_HOM_RR)] + nrd_mm[T2S(GT_HET_RA)] + nrd_mm[T2S(GT_HOM_AA)] + nrd_mm[T2S(GT_HET_AA)]; + printf("NRD%c\t2\t%f\t%f\t%f\t%f\n", x==0 ? 's' : 'i', + m+mm ? mm*100.0/(m+mm) : 0, + nrd_m[T2S(GT_HOM_RR)]+nrd_mm[T2S(GT_HOM_RR)] ? nrd_mm[T2S(GT_HOM_RR)]*100.0/(nrd_m[T2S(GT_HOM_RR)]+nrd_mm[T2S(GT_HOM_RR)]) : 0, + nrd_m[T2S(GT_HET_RA)]+nrd_mm[T2S(GT_HET_RA)] ? nrd_mm[T2S(GT_HET_RA)]*100.0/(nrd_m[T2S(GT_HET_RA)]+nrd_mm[T2S(GT_HET_RA)]) : 0, + nrd_m[T2S(GT_HOM_AA)]+nrd_mm[T2S(GT_HOM_AA)] ? nrd_mm[T2S(GT_HOM_AA)]*100.0/(nrd_m[T2S(GT_HOM_AA)]+nrd_mm[T2S(GT_HOM_AA)]) : 0 + ); + } + + for (x=0; x<2; x++) // x=0: snps, x=1: indels + { + gtcmp_t *stats; + if ( x==0 ) + { + printf("# GCsS, Genotype concordance by sample (SNPs)\n# GCsS\t[2]id\t[3]sample\t[4]non-reference discordance rate\t[5]RR Hom matches\t[6]RA Het matches\t[7]AA Hom matches\t[8]RR Hom mismatches\t[9]RA Het mismatches\t[10]AA Hom mismatches\t[11]dosage r-squared\n"); + stats = args->smpl_gts_snps; + } + else + { + printf("# GCiS, Genotype concordance by sample (indels)\n# GCiS\t[2]id\t[3]sample\t[4]non-reference discordance rate\t[5]RR Hom matches\t[6]RA Het matches\t[7]AA Hom matches\t[8]RR Hom mismatches\t[9]RA Het mismatches\t[10]AA Hom mismatches\t[11]dosage r-squared\n"); + stats = args->smpl_gts_indels; + } + for (i=0; ifiles->n_smpl; i++) + { + uint64_t mm = 0, m = stats[i].gt2gt[T2S(GT_HET_RA)][T2S(GT_HET_RA)] + stats[i].gt2gt[T2S(GT_HOM_AA)][T2S(GT_HOM_AA)]; + for (j=0; j<3; j++) + for (k=0; k<3; k++) + if ( j!=k ) mm += stats[i].gt2gt[j][k]; + + // Pearson's r2 + double r2 = 0; + if ( stats[i].n ) + { + r2 = (stats[i].yx - stats[i].x*stats[i].y/stats[i].n); + r2 /= sqrt((stats[i].xx - stats[i].x*stats[i].x/stats[i].n) * (stats[i].yy - stats[i].y*stats[i].y/stats[i].n)); + r2 *= r2; + } + printf("GC%cS\t2\t%s\t%.3f", x==0 ? 's' : 'i', args->files->samples[i], m+mm ? mm*100.0/(m+mm) : 0); + printf("\t%"PRId64"\t%"PRId64"\t%"PRId64"", + stats[i].gt2gt[T2S(GT_HOM_RR)][T2S(GT_HOM_RR)], + stats[i].gt2gt[T2S(GT_HET_RA)][T2S(GT_HET_RA)], + stats[i].gt2gt[T2S(GT_HOM_AA)][T2S(GT_HOM_AA)]); + printf("\t%"PRId64"\t%"PRId64"\t%"PRId64"", + stats[i].gt2gt[T2S(GT_HOM_RR)][T2S(GT_HET_RA)] + stats[i].gt2gt[T2S(GT_HOM_RR)][T2S(GT_HOM_AA)], + stats[i].gt2gt[T2S(GT_HET_RA)][T2S(GT_HOM_RR)] + stats[i].gt2gt[T2S(GT_HET_RA)][T2S(GT_HOM_AA)], + stats[i].gt2gt[T2S(GT_HOM_AA)][T2S(GT_HOM_RR)] + stats[i].gt2gt[T2S(GT_HOM_AA)][T2S(GT_HET_RA)]); + if ( stats[i].n && !isnan(r2) ) printf("\t%f\n", r2); + else printf("\t"NA_STRING"\n"); + } + } + for (x=0; x<2; x++) // x=0: snps, x=1: indels + { + //printf("# GCiS, Genotype concordance by sample (indels)\n# GCiS\t[2]id\t[3]sample\t[4]non-reference discordance rate\t[5]RR Hom matches\t[6]RA Het matches\t[7]AA Hom matches\t[8]RR Hom mismatches\t[9]RA Het mismatches\t[10]AA Hom mismatches\t[11]dosage r-squared\n"); + + gtcmp_t *stats; + if ( x==0 ) + { + printf("# GCTs, Genotype concordance table (SNPs)\n# GCTs"); + stats = args->smpl_gts_snps; + } + else + { + printf("# GCTi, Genotype concordance table (indels)\n# GCTi"); + stats = args->smpl_gts_indels; + } + i = 1; + printf("\t[%d]sample", ++i); + printf("\t[%d]RR Hom -> RR Hom", ++i); + printf("\t[%d]RR Hom -> RA Het", ++i); + printf("\t[%d]RR Hom -> AA Hom", ++i); + printf("\t[%d]RR Hom -> AA Het", ++i); + printf("\t[%d]RR Hom -> missing", ++i); + printf("\t[%d]RA Het -> RR Hom", ++i); + printf("\t[%d]RA Het -> RA Het", ++i); + printf("\t[%d]RA Het -> AA Hom", ++i); + printf("\t[%d]RA Het -> AA Het", ++i); + printf("\t[%d]RA Het -> missing", ++i); + printf("\t[%d]AA Hom -> RR Hom", ++i); + printf("\t[%d]AA Hom -> RA Het", ++i); + printf("\t[%d]AA Hom -> AA Hom", ++i); + printf("\t[%d]AA Hom -> AA Het", ++i); + printf("\t[%d]AA Hom -> missing", ++i); + printf("\t[%d]AA Het -> RR Hom", ++i); + printf("\t[%d]AA Het -> RA Het", ++i); + printf("\t[%d]AA Het -> AA Hom", ++i); + printf("\t[%d]AA Het -> AA Het", ++i); + printf("\t[%d]AA Het -> missing", ++i); + printf("\t[%d]missing -> RR Hom", ++i); + printf("\t[%d]missing -> RA Het", ++i); + printf("\t[%d]missing -> AA Hom", ++i); + printf("\t[%d]missing -> AA Het", ++i); + printf("\t[%d]missing -> missing\n", ++i); + + for (i=0; ifiles->n_smpl; i++) + { + printf("GCT%c\t%s", x==0 ? 's' : 'i', args->files->samples[i]); + for (j=0; j<5; j++) + for (k=0; k<5; k++) + printf("\t%"PRId64, stats[i].gt2gt[j][k]); + printf("\n"); + } + } + } + + printf("# DP, Depth distribution\n# DP\t[2]id\t[3]bin\t[4]number of genotypes\t[5]fraction of genotypes (%%)\t[6]number of sites\t[7]fraction of sites (%%)\n"); + for (id=0; idnstats; id++) + { + stats_t *stats = &args->stats[id]; + long unsigned int sum = 0, sum_sites = 0; + for (i=0; idp.m_vals; i++) { sum += stats->dp.vals[i]; sum_sites += stats->dp_sites.vals[i]; } + for (i=0; idp.m_vals; i++) + { + if ( stats->dp.vals[i]==0 && stats->dp_sites.vals[i]==0 ) continue; + printf("DP\t%d\t", id); + if ( i==0 ) printf("<%d", stats->dp.min); + else if ( i+1==stats->dp.m_vals ) printf(">%d", stats->dp.max); + else printf("%d", idist_i2bin(&stats->dp,i)); + printf("\t%"PRId64"\t%f", stats->dp.vals[i], sum ? stats->dp.vals[i]*100./sum : 0); + printf("\t%"PRId64"\t%f\n", stats->dp_sites.vals[i], sum_sites ? stats->dp_sites.vals[i]*100./sum_sites : 0); + } + } + + if ( args->files->n_smpl ) + { + printf("# PSC, Per-sample counts\n# PSC\t[2]id\t[3]sample\t[4]nRefHom\t[5]nNonRefHom\t[6]nHets\t[7]nTransitions\t[8]nTransversions\t[9]nIndels\t[10]average depth\t[11]nSingletons\n"); + for (id=0; idnstats; id++) + { + stats_t *stats = &args->stats[id]; + for (i=0; ifiles->n_smpl; i++) + { + float dp = stats->smpl_ndp[i] ? stats->smpl_dp[i]/(float)stats->smpl_ndp[i] : 0; + printf("PSC\t%d\t%s\t%d\t%d\t%d\t%d\t%d\t%d\t%.1f\t%d\n", id,args->files->samples[i], + stats->smpl_homRR[i], stats->smpl_homAA[i], stats->smpl_hets[i], stats->smpl_ts[i], + stats->smpl_tv[i], stats->smpl_indels[i],dp, stats->smpl_sngl[i]); + } + } + + + printf("# PSI, Per-Sample Indels\n# PSI\t[2]id\t[3]sample\t[4]in-frame\t[5]out-frame\t[6]not applicable\t[7]out/(in+out) ratio\t[8]nHets\t[9]nAA\n"); + for (id=0; idnstats; id++) + { + stats_t *stats = &args->stats[id]; + for (i=0; ifiles->n_smpl; i++) + { + int na = 0, in = 0, out = 0; + if ( args->exons ) + { + na = stats->smpl_frm_shifts[i*3 + 0]; + in = stats->smpl_frm_shifts[i*3 + 1]; + out = stats->smpl_frm_shifts[i*3 + 2]; + } + int nhom = stats->smpl_indel_homs[i]; + int nhet = stats->smpl_indel_hets[i]; + printf("PSI\t%d\t%s\t%d\t%d\t%d\t%.2f\t%d\t%d\n", id,args->files->samples[i], in,out,na,in+out?1.0*out/(in+out):0,nhet,nhom); + } + } + + #ifdef HWE_STATS + printf("# HWE\n# HWE\t[2]id\t[3]1st ALT allele frequency\t[4]Number of observations\t[5]25th percentile\t[6]median\t[7]75th percentile\n"); + for (id=0; idnstats; id++) + { + stats_t *stats = &args->stats[id]; + for (i=0; inaf_hwe; i++) stats->af_hwe[i+args->naf_hwe] += stats->af_hwe[i]; // singletons + for (i=1; im_af; i++) + { + unsigned int sum_tot = 0, sum_tmp = 0; + int j, *ptr = &stats->af_hwe[i*args->naf_hwe]; + for (j=0; jnaf_hwe; j++) sum_tot += ptr[j]; + if ( !sum_tot ) continue; + + double af = args->af_bins ? (bin_get_value(args->af_bins,i)+bin_get_value(args->af_bins,i-1))*0.5 : (double)(i-1)/(args->m_af-1); + + int nprn = 3; + printf("HWE\t%d\t%f\t%d",id,af,sum_tot); + for (j=0; jnaf_hwe; j++) + { + sum_tmp += ptr[j]; + float frac = (float)sum_tmp/sum_tot; + if ( frac >= 0.75 ) + { + while (nprn>0) { printf("\t%f", (float)j/args->naf_hwe); nprn--; } + break; + } + if ( frac >= 0.5 ) + { + while (nprn>1) { printf("\t%f", (float)j/args->naf_hwe); nprn--; } + continue; + } + if ( frac >= 0.25 ) + { + while (nprn>2) { printf("\t%f", (float)j/args->naf_hwe); nprn--; } + } + } + assert(nprn==0); + printf("\n"); + } + } + #endif + } +} + +static void usage(void) +{ + fprintf(stderr, "\n"); + fprintf(stderr, "About: Parses VCF or BCF and produces stats which can be plotted using plot-vcfstats.\n"); + fprintf(stderr, " When two files are given, the program generates separate stats for intersection\n"); + fprintf(stderr, " and the complements. By default only sites are compared, -s/-S must given to include\n"); + fprintf(stderr, " also sample columns.\n"); + fprintf(stderr, "Usage: bcftools stats [options] []\n"); + fprintf(stderr, "\n"); + fprintf(stderr, "Options:\n"); + fprintf(stderr, " --af-bins allele frequency bins, a list (0.1,0.5,1) or a file (0.1\\n0.5\\n1)\n"); + fprintf(stderr, " --af-tag allele frequency tag to use, by default estimated from AN,AC or GT\n"); + fprintf(stderr, " -1, --1st-allele-only include only 1st allele at multiallelic sites\n"); + fprintf(stderr, " -c, --collapse treat as identical records with , see man page for details [none]\n"); + fprintf(stderr, " -d, --depth depth distribution: min,max,bin size [0,500,1]\n"); + fprintf(stderr, " -e, --exclude exclude sites for which the expression is true (see man page for details)\n"); + fprintf(stderr, " -E, --exons tab-delimited file with exons for indel frameshifts (chr,from,to; 1-based, inclusive, bgzip compressed)\n"); + fprintf(stderr, " -f, --apply-filters require at least one of the listed FILTER strings (e.g. \"PASS,.\")\n"); + fprintf(stderr, " -F, --fasta-ref faidx indexed reference sequence file to determine INDEL context\n"); + fprintf(stderr, " -i, --include select sites for which the expression is true (see man page for details)\n"); + fprintf(stderr, " -I, --split-by-ID collect stats for sites with ID separately (known vs novel)\n"); + fprintf(stderr, " -r, --regions restrict to comma-separated list of regions\n"); + fprintf(stderr, " -R, --regions-file restrict to regions listed in a file\n"); + fprintf(stderr, " -s, --samples list of samples for sample stats, \"-\" to include all samples\n"); + fprintf(stderr, " -S, --samples-file file of samples to include\n"); + fprintf(stderr, " -t, --targets similar to -r but streams rather than index-jumps\n"); + fprintf(stderr, " -T, --targets-file similar to -R but streams rather than index-jumps\n"); + fprintf(stderr, " -u, --user-tstv collect Ts/Tv stats for any tag using the given binning [0:1:100]\n"); + fprintf(stderr, " --threads number of extra decompression threads [0]\n"); + fprintf(stderr, " -v, --verbose produce verbose per-site and per-sample output\n"); + fprintf(stderr, "\n"); + exit(1); +} + +int main_vcfstats(int argc, char *argv[]) +{ + int c; + args_t *args = (args_t*) calloc(1,sizeof(args_t)); + args->files = bcf_sr_init(); + args->argc = argc; args->argv = argv; + args->dp_min = 0; args->dp_max = 500; args->dp_step = 1; + int regions_is_file = 0, targets_is_file = 0; + + static struct option loptions[] = + { + {"af-bins",1,0,1}, + {"af-tag",1,0,2}, + {"1st-allele-only",0,0,'1'}, + {"include",1,0,'i'}, + {"exclude",1,0,'e'}, + {"help",0,0,'h'}, + {"collapse",1,0,'c'}, + {"regions",1,0,'r'}, + {"regions-file",1,0,'R'}, + {"verbose",0,0,'v'}, + {"depth",1,0,'d'}, + {"apply-filters",1,0,'f'}, + {"exons",1,0,'E'}, + {"samples",1,0,'s'}, + {"samples-file",1,0,'S'}, + {"split-by-ID",0,0,'I'}, + {"targets",1,0,'t'}, + {"targets-file",1,0,'T'}, + {"fasta-ref",1,0,'F'}, + {"user-tstv",1,0,'u'}, + {"threads",1,0,9}, + {0,0,0,0} + }; + while ((c = getopt_long(argc, argv, "hc:r:R:e:s:S:d:i:t:T:F:f:1u:vIE:",loptions,NULL)) >= 0) { + switch (c) { + case 1 : args->af_bins_list = optarg; break; + case 2 : args->af_tag = optarg; break; + case 'u': add_user_stats(args,optarg); break; + case '1': args->first_allele_only = 1; break; + case 'F': args->ref_fname = optarg; break; + case 't': args->targets_list = optarg; break; + case 'T': args->targets_list = optarg; targets_is_file = 1; break; + case 'c': + if ( !strcmp(optarg,"snps") ) args->files->collapse |= COLLAPSE_SNPS; + else if ( !strcmp(optarg,"indels") ) args->files->collapse |= COLLAPSE_INDELS; + else if ( !strcmp(optarg,"both") ) args->files->collapse |= COLLAPSE_SNPS | COLLAPSE_INDELS; + else if ( !strcmp(optarg,"any") ) args->files->collapse |= COLLAPSE_ANY; + else if ( !strcmp(optarg,"all") ) args->files->collapse |= COLLAPSE_ANY; + else if ( !strcmp(optarg,"some") ) args->files->collapse |= COLLAPSE_SOME; + else if ( !strcmp(optarg,"none") ) args->files->collapse = COLLAPSE_NONE; + else error("The --collapse string \"%s\" not recognised.\n", optarg); + break; + case 'v': args->verbose_sites = 1; break; + case 'd': + if ( sscanf(optarg,"%d,%d,%d",&args->dp_min,&args->dp_max,&args->dp_step)!=3 ) + error("Could not parse --depth %s\n", optarg); + if ( args->dp_min<0 || args->dp_min >= args->dp_max || args->dp_step > args->dp_max - args->dp_min + 1 ) + error("Is this a typo? --depth %s\n", optarg); + break; + case 'f': args->files->apply_filters = optarg; break; + case 'r': args->regions_list = optarg; break; + case 'R': args->regions_list = optarg; regions_is_file = 1; break; + case 'E': args->exons_fname = optarg; break; + case 's': args->samples_list = optarg; break; + case 'S': args->samples_list = optarg; args->samples_is_file = 1; break; + case 'I': args->split_by_id = 1; break; + case 'e': args->filter_str = optarg; args->filter_logic |= FLT_EXCLUDE; break; + case 'i': args->filter_str = optarg; args->filter_logic |= FLT_INCLUDE; break; + case 9 : args->n_threads = strtol(optarg, 0, 0); break; + case 'h': + case '?': usage(); + default: error("Unknown argument: %s\n", optarg); + } + } + char *fname = NULL; + if ( optind==argc ) + { + if ( !isatty(fileno((FILE *)stdin)) ) fname = "-"; // reading from stdin + else usage(); + } + else fname = argv[optind]; + + if ( argc-optind>2 ) usage(); + if ( argc-optind>1 ) + { + args->files->require_index = 1; + if ( args->split_by_id ) error("Only one file can be given with -i.\n"); + } + if ( !args->samples_list ) args->files->max_unpack = BCF_UN_INFO; + if ( args->targets_list && bcf_sr_set_targets(args->files, args->targets_list, targets_is_file, 0)<0 ) + error("Failed to read the targets: %s\n", args->targets_list); + if ( args->regions_list && bcf_sr_set_regions(args->files, args->regions_list, regions_is_file)<0 ) + error("Failed to read the regions: %s\n", args->regions_list); + if ( args->n_threads && bcf_sr_set_threads(args->files, args->n_threads)<0) + error("Failed to create threads\n"); + + while (fname) + { + if ( !bcf_sr_add_reader(args->files, fname) ) + error("Failed to open %s: %s\n", fname,bcf_sr_strerror(args->files->errnum)); + fname = ++optind < argc ? argv[optind] : NULL; + } + + init_stats(args); + print_header(args); + do_vcf_stats(args); + print_stats(args); + destroy_stats(args); + bcf_sr_destroy(args->files); + free(args); + return 0; +} + diff --git a/vcfview.c b/vcfview.c new file mode 100644 index 0000000..645cc8a --- /dev/null +++ b/vcfview.c @@ -0,0 +1,764 @@ +/* vcfview.c -- VCF/BCF conversion, view, subset and filter VCF/BCF files. + + Copyright (C) 2013-2014 Genome Research Ltd. + + Author: Shane McCarthy + +Permission is hereby granted, free of charge, to any person obtaining a copy +of this software and associated documentation files (the "Software"), to deal +in the Software without restriction, including without limitation the rights +to use, copy, modify, merge, publish, distribute, sublicense, and/or sell +copies of the Software, and to permit persons to whom the Software is +furnished to do so, subject to the following conditions: + +The above copyright notice and this permission notice shall be included in +all copies or substantial portions of the Software. + +THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE +AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER +LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, +OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN +THE SOFTWARE. */ + +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include +#include "bcftools.h" +#include "filter.h" +#include "htslib/khash_str2int.h" + +#define FLT_INCLUDE 1 +#define FLT_EXCLUDE 2 + +#define ALLELE_NONREF 1 +#define ALLELE_MINOR 2 +#define ALLELE_ALT1 3 +#define ALLELE_MAJOR 4 +#define ALLELE_NONMAJOR 5 + +#define GT_NEED_HOM 1 +#define GT_NEED_HET 2 +#define GT_NO_HOM 3 +#define GT_NO_HET 4 +#define GT_NEED_MISSING 5 +#define GT_NO_MISSING 6 + +typedef struct _args_t +{ + filter_t *filter; + char *filter_str; + int filter_logic; // one of FLT_INCLUDE/FLT_EXCLUDE (-i or -e) + + bcf_srs_t *files; + bcf_hdr_t *hdr, *hnull, *hsub; // original header, sites-only header, subset header + char **argv, *format, *sample_names, *subset_fname, *targets_list, *regions_list; + int argc, clevel, n_threads, output_type, print_header, update_info, header_only, n_samples, *imap, calc_ac; + int trim_alts, sites_only, known, novel, min_alleles, max_alleles, private_vars, uncalled, phased; + int min_ac, min_ac_type, max_ac, max_ac_type, min_af_type, max_af_type, gt_type; + int *ac, mac; + float min_af, max_af; + char *fn_ref, *fn_out, **samples; + int sample_is_file, force_samples; + char *include_types, *exclude_types; + int include, exclude; + int record_cmd_line; + htsFile *out; +} +args_t; + +static void init_data(args_t *args) +{ + int i; + args->hdr = args->files->readers[0].header; + + if (args->calc_ac && args->update_info) + { + bcf_hdr_append(args->hdr,"##INFO="); + bcf_hdr_append(args->hdr,"##INFO="); + } + if (args->record_cmd_line) bcf_hdr_append_version(args->hdr, args->argc, args->argv, "bcftools_view"); + else bcf_hdr_sync(args->hdr); + + // setup sample data + if (args->sample_names) + { + void *hdr_samples = khash_str2int_init(); + for (i=0; ihdr); i++) + khash_str2int_inc(hdr_samples, bcf_hdr_int2id(args->hdr,BCF_DT_SAMPLE,i)); + + void *exclude = (args->sample_names[0]=='^') ? khash_str2int_init() : NULL; + int nsmpl; + char **smpl = NULL; + args->samples = NULL; args->n_samples = 0; + smpl = hts_readlist(exclude ? &args->sample_names[1] : args->sample_names, args->sample_is_file, &nsmpl); + if ( !smpl ) + { + error("Could not read the list: \"%s\"\n", exclude ? &args->sample_names[1] : args->sample_names); + } + + if ( exclude ) + { + for (i=0; iforce_samples) { + fprintf(stderr, "Warn: exclude called for sample that does not exist in header: \"%s\"... skipping\n", smpl[i]); + } else { + error("Error: exclude called for sample that does not exist in header: \"%s\". Use \"--force-samples\" to ignore this error.\n", smpl[i]); + } + } + khash_str2int_inc(exclude, smpl[i]); + } + + for (i=0; ihdr); i++) + { + if ( exclude && khash_str2int_has_key(exclude,bcf_hdr_int2id(args->hdr,BCF_DT_SAMPLE,i)) ) continue; + args->samples = (char**) realloc(args->samples, (args->n_samples+1)*sizeof(const char*)); + args->samples[args->n_samples++] = strdup(bcf_hdr_int2id(args->hdr,BCF_DT_SAMPLE,i)); + } + khash_str2int_destroy(exclude); + } + else + { + for (i=0; iforce_samples) { + fprintf(stderr, "Warn: subset called for sample that does not exist in header: \"%s\"... skipping\n", smpl[i]); + continue; + } else { + error("Error: subset called for sample that does not exist in header: \"%s\". Use \"--force-samples\" to ignore this error.\n", smpl[i]); + } + } + args->samples = (char**) realloc(args->samples, (args->n_samples+1)*sizeof(const char*)); + args->samples[args->n_samples++] = strdup(smpl[i]); + } + } + for (i=0; in_samples == 0) { + fprintf(stderr, "Warn: subsetting has removed all samples\n"); + args->sites_only = 1; + } + } + + if (args->n_samples) + args->imap = (int*)malloc(args->n_samples * sizeof(int)); + + // determine variant types to include/exclude + if (args->include_types || args->exclude_types) { + if (args->include_types && args->exclude_types) { + fprintf(stderr, "Error: only supply one of --include-types, --exclude-types options\n"); + exit(1); + } + char **type_list = 0; + int m = 0, n = 0; + const char *q, *p; + for (q = p = args->include_types ? args->include_types : args->exclude_types;; ++p) { + if (*p == ',' || *p == 0) { + if (m == n) { + m = m? m<<1 : 16; + type_list = (char**)realloc(type_list, m * sizeof(char*)); + } + type_list[n] = (char*)calloc(p - q + 1, 1); + strncpy(type_list[n++], q, p - q); + q = p + 1; + if (*p == 0) break; + } + } + type_list = (char**)realloc(type_list, n * sizeof(char*)); + + if (args->include_types) { + args->include = 0; + for (i = 0; i < n; ++i) { + if (strcmp(type_list[i], "snps") == 0) args->include |= VCF_SNP<<1; + else if (strcmp(type_list[i], "indels") == 0) args->include |= VCF_INDEL<<1; + else if (strcmp(type_list[i], "mnps") == 0) args->include |= VCF_MNP<<1; + else if (strcmp(type_list[i], "other") == 0) args->include |= VCF_OTHER<<1; + else if (strcmp(type_list[i], "ref") == 0) args->include |= VCF_OTHER<<1; + else if (strcmp(type_list[i], "bnd") == 0) args->include |= VCF_BND<<1; + else { + fprintf(stderr, "[E::%s] unknown type\n", type_list[i]); + fprintf(stderr, "Accepted types are snps, indels, mnps, other\n"); + exit(1); + } + } + } + if (args->exclude_types) { + args->exclude = 0; + for (i = 0; i < n; ++i) { + if (strcmp(type_list[i], "snps") == 0) args->exclude |= VCF_SNP<<1; + else if (strcmp(type_list[i], "indels") == 0) args->exclude |= VCF_INDEL<<1; + else if (strcmp(type_list[i], "mnps") == 0) args->exclude |= VCF_MNP<<1; + else if (strcmp(type_list[i], "other") == 0) args->exclude |= VCF_OTHER<<1; + else if (strcmp(type_list[i], "ref") == 0) args->exclude |= VCF_OTHER<<1; + else if (strcmp(type_list[i], "bnd") == 0) args->exclude |= VCF_BND<<1; + else { + fprintf(stderr, "[E::%s] unknown type\n", type_list[i]); + fprintf(stderr, "Accepted types are snps, indels, mnps, other\n"); + exit(1); + } + } + } + for (i = 0; i < n; ++i) + free(type_list[i]); + free(type_list); + } + + // setup output + char modew[8]; + strcpy(modew, "w"); + if (args->clevel >= 0 && args->clevel <= 9) sprintf(modew + 1, "%d", args->clevel); + if (args->output_type==FT_BCF) strcat(modew, "bu"); // uncompressed BCF + else if (args->output_type & FT_BCF) strcat(modew, "b"); // compressed BCF + else if (args->output_type & FT_GZ) strcat(modew,"z"); // compressed VCF + args->out = hts_open(args->fn_out ? args->fn_out : "-", modew); + if ( !args->out ) error("%s: %s\n", args->fn_out,strerror(errno)); + if ( args->n_threads > 0) + hts_set_opt(args->out, HTS_OPT_THREAD_POOL, args->files->p); + + // headers: hdr=full header, hsub=subset header, hnull=sites only header + if (args->sites_only){ + args->hnull = bcf_hdr_subset(args->hdr, 0, 0, 0); + bcf_hdr_remove(args->hnull, BCF_HL_FMT, NULL); + } + if (args->n_samples > 0) + { + args->hsub = bcf_hdr_subset(args->hdr, args->n_samples, args->samples, args->imap); + if ( !args->hsub ) error("Error occurred while subsetting samples\n"); + if ( args->n_samples != bcf_hdr_nsamples(args->hsub) ) + { + int i; + for (i=0; in_samples; i++) + if ( args->imap[i]<0 ) error("Error: No such sample: \"%s\"\n", args->samples[i]); + } + } + + if ( args->filter_str ) + args->filter = filter_init(args->hdr, args->filter_str); +} + +static void destroy_data(args_t *args) +{ + int i; + if ( args->imap ) { + for (i = 0; i < args->n_samples; ++i) + free(args->samples[i]); + free(args->samples); + free(args->imap); + } + if (args->hnull) bcf_hdr_destroy(args->hnull); + if (args->hsub) bcf_hdr_destroy(args->hsub); + if ( args->filter ) + filter_destroy(args->filter); + free(args->ac); +} + +// true if all samples are phased. +// haploid genotypes are considered phased +// ./. => not phased, .|. => phased +int bcf_all_phased(const bcf_hdr_t *header, bcf1_t *line) +{ + bcf_unpack(line, BCF_UN_FMT); + bcf_fmt_t *fmt_ptr = bcf_get_fmt(header, line, "GT"); + int all_phased = 1; + if ( fmt_ptr ) + { + int i, isample; + for (isample=0; isamplen_sample; isample++) + { + int sample_phased = 0; + #define BRANCH_INT(type_t,vector_end) { \ + type_t *p = (type_t*) (fmt_ptr->p + isample*fmt_ptr->size); \ + for (i=0; in; i++) \ + { \ + if (fmt_ptr->n == 1 || (p[i] == vector_end && i == 1)) { sample_phased = 1; break; } /* haploid phased by definition */ \ + if ( p[i] == vector_end ) { break; }; /* smaller ploidy */ \ + if ( bcf_gt_is_missing(p[i]) ) continue; /* missing allele */ \ + if ((p[i])&1) { \ + sample_phased = 1; \ + break; \ + } \ + } \ + } + switch (fmt_ptr->type) { + case BCF_BT_INT8: BRANCH_INT(int8_t, bcf_int8_vector_end); break; + case BCF_BT_INT16: BRANCH_INT(int16_t, bcf_int16_vector_end); break; + case BCF_BT_INT32: BRANCH_INT(int32_t, bcf_int32_vector_end); break; + default: fprintf(stderr, "[E::%s] todo: fmt_type %d\n", __func__, fmt_ptr->type); exit(1); break; + } + #undef BRANCH_INT + if (!sample_phased) { + all_phased = 0; + break; + } + } + } + return all_phased; +} + +int subset_vcf(args_t *args, bcf1_t *line) +{ + if ( args->min_alleles && line->n_allele < args->min_alleles ) return 0; // min alleles + if ( args->max_alleles && line->n_allele > args->max_alleles ) return 0; // max alleles + if (args->novel || args->known) + { + if ( args->novel && (line->d.id[0]!='.' || line->d.id[1]!=0) ) return 0; // skip sites which are known, ID != '.' + if ( args->known && line->d.id[0]=='.' && line->d.id[1]==0 ) return 0; // skip sites which are novel, ID == '.' + } + + if (args->include || args->exclude) + { + int line_type = bcf_get_variant_types(line); + if ( args->include && !((line_type<<1) & args->include) ) return 0; // include only given variant types + if ( args->exclude && (line_type<<1) & args->exclude ) return 0; // exclude given variant types + } + + if ( args->filter ) + { + int ret = filter_test(args->filter, line, NULL); + if ( args->filter_logic==FLT_INCLUDE ) { if ( !ret ) return 0; } + else if ( ret ) return 0; + } + + hts_expand(int, line->n_allele, args->mac, args->ac); + int i, an = 0, non_ref_ac = 0; + if (args->calc_ac) { + bcf_calc_ac(args->hdr, line, args->ac, BCF_UN_INFO|BCF_UN_FMT); // get original AC and AN values from INFO field if available, otherwise calculate + for (i=1; in_allele; i++) + non_ref_ac += args->ac[i]; + for (i=0; in_allele; i++) + an += args->ac[i]; + } + + if (args->n_samples) + { + int non_ref_ac_sub = 0, *ac_sub = (int*) calloc(line->n_allele,sizeof(int)); + bcf_subset(args->hdr, line, args->n_samples, args->imap); + if (args->calc_ac) { + bcf_calc_ac(args->hsub, line, ac_sub, BCF_UN_FMT); // recalculate AC and AN + an = 0; + for (i=0; in_allele; i++) { + args->ac[i] = ac_sub[i]; + an += ac_sub[i]; + } + for (i=1; in_allele; i++) + non_ref_ac_sub += ac_sub[i]; + if (args->private_vars) { + if (args->private_vars == FLT_INCLUDE && !(non_ref_ac_sub > 0 && non_ref_ac == non_ref_ac_sub)) { free(ac_sub); return 0; } // select private sites + if (args->private_vars == FLT_EXCLUDE && non_ref_ac_sub > 0 && non_ref_ac == non_ref_ac_sub) { free(ac_sub); return 0; } // exclude private sites + } + non_ref_ac = non_ref_ac_sub; + } + free(ac_sub); + } + + bcf_fmt_t *gt_fmt; + if ( args->gt_type && (gt_fmt=bcf_get_fmt(args->hdr,line,"GT")) ) + { + int nhet = 0, nhom = 0, nmiss = 0; + for (i=0; ihdr); i++) + { + int type = bcf_gt_type(gt_fmt,i,NULL,NULL); + if ( type==GT_HET_RA || type==GT_HET_AA ) + { + if ( args->gt_type==GT_NO_HET ) return 0; + nhet = 1; + } + else if ( type==GT_UNKN ) + { + if ( args->gt_type==GT_NO_MISSING ) return 0; + nmiss = 1; + } + else + { + if ( args->gt_type==GT_NO_HOM ) return 0; + nhom = 1; + } + } + if ( args->gt_type==GT_NEED_HOM && !nhom ) return 0; + else if ( args->gt_type==GT_NEED_HET && !nhet ) return 0; + else if ( args->gt_type==GT_NEED_MISSING && !nmiss ) return 0; + } + + int minor_ac = 0; + int major_ac = 0; + if ( args->calc_ac ) + { + minor_ac = args->ac[0]; + major_ac = args->ac[0]; + for (i=1; in_allele; i++){ + if (args->ac[i] < minor_ac) { minor_ac = args->ac[i]; } + if (args->ac[i] > major_ac) { major_ac = args->ac[i]; } + } + } + + if (args->min_ac!=-1) + { + if (args->min_ac_type == ALLELE_NONREF && args->min_ac>non_ref_ac) return 0; // min AC + else if (args->min_ac_type == ALLELE_MINOR && args->min_ac>minor_ac) return 0; // min minor AC + else if (args->min_ac_type == ALLELE_ALT1 && args->min_ac>args->ac[1]) return 0; // min 1st alternate AC + else if (args->min_ac_type == ALLELE_MAJOR && args->min_ac > major_ac) return 0; // min major AC + else if (args->min_ac_type == ALLELE_NONMAJOR && args->min_ac > an-major_ac) return 0; // min non-major AC + } + if (args->max_ac!=-1) + { + if (args->max_ac_type == ALLELE_NONREF && args->max_acmax_ac_type == ALLELE_MINOR && args->max_acmax_ac_type == ALLELE_ALT1 && args->max_acac[1]) return 0; // max 1st alternate AC + else if (args->max_ac_type == ALLELE_MAJOR && args->max_ac < major_ac) return 0; // max major AC + else if (args->max_ac_type == ALLELE_NONMAJOR && args->max_ac < an-major_ac) return 0; // max non-major AC + } + if (args->min_af!=-1) + { + if (an == 0) return 0; // freq not defined, skip site + if (args->min_af_type == ALLELE_NONREF && args->min_af>non_ref_ac/(double)an) return 0; // min AF + else if (args->min_af_type == ALLELE_MINOR && args->min_af>minor_ac/(double)an) return 0; // min minor AF + else if (args->min_af_type == ALLELE_ALT1 && args->min_af>args->ac[1]/(double)an) return 0; // min 1st alternate AF + else if (args->min_af_type == ALLELE_MAJOR && args->min_af > major_ac/(double)an) return 0; // min major AF + else if (args->min_af_type == ALLELE_NONMAJOR && args->min_af > (an-major_ac)/(double)an) return 0; // min non-major AF + } + if (args->max_af!=-1) + { + if (an == 0) return 0; // freq not defined, skip site + if (args->max_af_type == ALLELE_NONREF && args->max_afmax_af_type == ALLELE_MINOR && args->max_afmax_af_type == ALLELE_ALT1 && args->max_afac[1]/(double)an) return 0; // max 1st alternate AF + else if (args->max_af_type == ALLELE_MAJOR && args->max_af < major_ac/(double)an) return 0; // max major AF + else if (args->max_af_type == ALLELE_NONMAJOR && args->max_af < (an-major_ac)/(double)an) return 0; // max non-major AF + } + if (args->uncalled) { + if (args->uncalled == FLT_INCLUDE && an > 0) return 0; // select uncalled + if (args->uncalled == FLT_EXCLUDE && an == 0) return 0; // skip if uncalled + } + if (args->calc_ac && args->update_info) { + bcf_update_info_int32(args->hdr, line, "AC", &args->ac[1], line->n_allele-1); + bcf_update_info_int32(args->hdr, line, "AN", &an, 1); + } + if (args->trim_alts) + { + int ret = bcf_trim_alleles(args->hsub ? args->hsub : args->hdr, line); + if ( ret<0 ) error("Error: Could not trim alleles at %s:%d\n", bcf_seqname(args->hsub ? args->hsub : args->hdr, line), line->pos+1); + } + if (args->phased) { + int phased = bcf_all_phased(args->hdr, line); + if (args->phased == FLT_INCLUDE && !phased) { return 0; } // skip unphased + if (args->phased == FLT_EXCLUDE && phased) { return 0; } // skip phased + } + if (args->sites_only) bcf_subset(args->hsub ? args->hsub : args->hdr, line, 0, 0); + return 1; +} + +void set_allele_type (int *atype, char *atype_string) +{ + *atype = ALLELE_NONREF; + if (strcmp(atype_string, "minor") == 0) { + *atype = ALLELE_MINOR; + } + else if (strcmp(atype_string, "alt1") == 0) { + *atype = ALLELE_ALT1; + } + else if (strcmp(atype_string, "nref") == 0) { + *atype = ALLELE_NONREF; + } + else if (strcmp(atype_string, "major") == 0) { + *atype = ALLELE_MAJOR; + } + else if (strcmp(atype_string, "nonmajor") == 0) { + *atype = ALLELE_NONMAJOR; + } + else { + error("Error: allele type not recognised. Expected one of nref|alt1|minor|major|nonmajor, got \"%s\".\n", atype_string); + } +} + +static void usage(args_t *args) +{ + fprintf(stderr, "\n"); + fprintf(stderr, "About: VCF/BCF conversion, view, subset and filter VCF/BCF files.\n"); + fprintf(stderr, "Usage: bcftools view [options] [region1 [...]]\n"); + fprintf(stderr, "\n"); + fprintf(stderr, "Output options:\n"); + fprintf(stderr, " -G, --drop-genotypes drop individual genotype information (after subsetting if -s option set)\n"); + fprintf(stderr, " -h/H, --header-only/--no-header print the header only/suppress the header in VCF output\n"); + fprintf(stderr, " -l, --compression-level [0-9] compression level: 0 uncompressed, 1 best speed, 9 best compression [%d]\n", args->clevel); + fprintf(stderr, " --no-version do not append version and command line to the header\n"); + fprintf(stderr, " -o, --output-file output file name [stdout]\n"); + fprintf(stderr, " -O, --output-type b: compressed BCF, u: uncompressed BCF, z: compressed VCF, v: uncompressed VCF [v]\n"); + fprintf(stderr, " -r, --regions restrict to comma-separated list of regions\n"); + fprintf(stderr, " -R, --regions-file restrict to regions listed in a file\n"); + fprintf(stderr, " -t, --targets [^] similar to -r but streams rather than index-jumps. Exclude regions with \"^\" prefix\n"); + fprintf(stderr, " -T, --targets-file [^] similar to -R but streams rather than index-jumps. Exclude regions with \"^\" prefix\n"); + fprintf(stderr, " --threads number of extra (de)compression threads [0]\n"); + fprintf(stderr, "\n"); + fprintf(stderr, "Subset options:\n"); + fprintf(stderr, " -a, --trim-alt-alleles trim alternate alleles not seen in the subset\n"); + fprintf(stderr, " -I, --no-update do not (re)calculate INFO fields for the subset (currently INFO/AC and INFO/AN)\n"); + fprintf(stderr, " -s, --samples [^] comma separated list of samples to include (or exclude with \"^\" prefix)\n"); + fprintf(stderr, " -S, --samples-file [^] file of samples to include (or exclude with \"^\" prefix)\n"); + fprintf(stderr, " --force-samples only warn about unknown subset samples\n"); + fprintf(stderr, "\n"); + fprintf(stderr, "Filter options:\n"); + fprintf(stderr, " -c/C, --min-ac/--max-ac [:] minimum/maximum count for non-reference (nref), 1st alternate (alt1), least frequent\n"); + fprintf(stderr, " (minor), most frequent (major) or sum of all but most frequent (nonmajor) alleles [nref]\n"); + fprintf(stderr, " -f, --apply-filters require at least one of the listed FILTER strings (e.g. \"PASS,.\")\n"); + fprintf(stderr, " -g, --genotype [^] require one or more hom/het/missing genotype or, if prefixed with \"^\", exclude sites with hom/het/missing genotypes\n"); + fprintf(stderr, " -i/e, --include/--exclude select/exclude sites for which the expression is true (see man page for details)\n"); + fprintf(stderr, " -k/n, --known/--novel select known/novel sites only (ID is not/is '.')\n"); + fprintf(stderr, " -m/M, --min-alleles/--max-alleles minimum/maximum number of alleles listed in REF and ALT (e.g. -m2 -M2 for biallelic sites)\n"); + fprintf(stderr, " -p/P, --phased/--exclude-phased select/exclude sites where all samples are phased\n"); + fprintf(stderr, " -q/Q, --min-af/--max-af [:] minimum/maximum frequency for non-reference (nref), 1st alternate (alt1), least frequent\n"); + fprintf(stderr, " (minor), most frequent (major) or sum of all but most frequent (nonmajor) alleles [nref]\n"); + fprintf(stderr, " -u/U, --uncalled/--exclude-uncalled select/exclude sites without a called genotype\n"); + fprintf(stderr, " -v/V, --types/--exclude-types select/exclude comma-separated list of variant types: snps,indels,mnps,ref,bnd,other [null]\n"); + fprintf(stderr, " -x/X, --private/--exclude-private select/exclude sites where the non-reference alleles are exclusive (private) to the subset samples\n"); + fprintf(stderr, "\n"); + exit(1); +} + +int main_vcfview(int argc, char *argv[]) +{ + int c; + args_t *args = (args_t*) calloc(1,sizeof(args_t)); + args->argc = argc; args->argv = argv; + args->files = bcf_sr_init(); + args->clevel = -1; + args->print_header = 1; + args->update_info = 1; + args->output_type = FT_VCF; + args->n_threads = 0; + args->record_cmd_line = 1; + args->min_ac = args->max_ac = args->min_af = args->max_af = -1; + int targets_is_file = 0, regions_is_file = 0; + + static struct option loptions[] = + { + {"genotype",required_argument,NULL,'g'}, + {"compression-level",required_argument,NULL,'l'}, + {"threads",required_argument,NULL,9}, + {"header-only",no_argument,NULL,'h'}, + {"no-header",no_argument,NULL,'H'}, + {"exclude",required_argument,NULL,'e'}, + {"include",required_argument,NULL,'i'}, + {"trim-alt-alleles",no_argument,NULL,'a'}, + {"no-update",no_argument,NULL,'I'}, + {"drop-genotypes",no_argument,NULL,'G'}, + {"private",no_argument,NULL,'x'}, + {"exclude-private",no_argument,NULL,'X'}, + {"uncalled",no_argument,NULL,'u'}, + {"exclude-uncalled",no_argument,NULL,'U'}, + {"apply-filters",required_argument,NULL,'f'}, + {"known",no_argument,NULL,'k'}, + {"novel",no_argument,NULL,'n'}, + {"min-alleles",required_argument,NULL,'m'}, + {"max-alleles",required_argument,NULL,'M'}, + {"samples",required_argument,NULL,'s'}, + {"samples-file",required_argument,NULL,'S'}, + {"force-samples",no_argument,NULL,1}, + {"output-type",required_argument,NULL,'O'}, + {"output-file",required_argument,NULL,'o'}, + {"types",required_argument,NULL,'v'}, + {"exclude-types",required_argument,NULL,'V'}, + {"targets",required_argument,NULL,'t'}, + {"targets-file",required_argument,NULL,'T'}, + {"regions",required_argument,NULL,'r'}, + {"regions-file",required_argument,NULL,'R'}, + {"min-ac",required_argument,NULL,'c'}, + {"max-ac",required_argument,NULL,'C'}, + {"min-af",required_argument,NULL,'q'}, + {"max-af",required_argument,NULL,'Q'}, + {"phased",no_argument,NULL,'p'}, + {"exclude-phased",no_argument,NULL,'P'}, + {"no-version",no_argument,NULL,8}, + {NULL,0,NULL,0} + }; + char *tmp; + while ((c = getopt_long(argc, argv, "l:t:T:r:R:o:O:s:S:Gf:knv:V:m:M:auUhHc:C:Ii:e:xXpPq:Q:g:",loptions,NULL)) >= 0) + { + char allele_type[8] = "nref"; + switch (c) + { + case 'O': + switch (optarg[0]) { + case 'b': args->output_type = FT_BCF_GZ; break; + case 'u': args->output_type = FT_BCF; break; + case 'z': args->output_type = FT_VCF_GZ; break; + case 'v': args->output_type = FT_VCF; break; + default: error("The output type \"%s\" not recognised\n", optarg); + }; + break; + case 'l': + args->clevel = strtol(optarg,&tmp,10); + if ( *tmp ) error("Could not parse argument: --compression-level %s\n", optarg); + args->output_type |= FT_GZ; + break; + case 'o': args->fn_out = optarg; break; + case 'H': args->print_header = 0; break; + case 'h': args->header_only = 1; break; + + case 't': args->targets_list = optarg; break; + case 'T': args->targets_list = optarg; targets_is_file = 1; break; + case 'r': args->regions_list = optarg; break; + case 'R': args->regions_list = optarg; regions_is_file = 1; break; + + case 's': args->sample_names = optarg; break; + case 'S': args->sample_names = optarg; args->sample_is_file = 1; break; + case 1 : args->force_samples = 1; break; + case 'a': args->trim_alts = 1; args->calc_ac = 1; break; + case 'I': args->update_info = 0; break; + case 'G': args->sites_only = 1; break; + + case 'f': args->files->apply_filters = optarg; break; + case 'k': args->known = 1; break; + case 'n': args->novel = 1; break; + case 'm': + args->min_alleles = strtol(optarg,&tmp,10); + if ( *tmp ) error("Could not parse argument: --min-alleles %s\n", optarg); + break; + case 'M': + args->max_alleles = strtol(optarg,&tmp,10); + if ( *tmp ) error("Could not parse argument: --max-alleles %s\n", optarg); + break; + case 'v': args->include_types = optarg; break; + case 'V': args->exclude_types = optarg; break; + case 'e': args->filter_str = optarg; args->filter_logic |= FLT_EXCLUDE; break; + case 'i': args->filter_str = optarg; args->filter_logic |= FLT_INCLUDE; break; + + case 'c': + { + args->min_ac_type = ALLELE_NONREF; + if ( sscanf(optarg,"%d:%s",&args->min_ac, allele_type)!=2 && sscanf(optarg,"%d",&args->min_ac)!=1 ) + error("Error: Could not parse --min-ac %s\n", optarg); + set_allele_type(&args->min_ac_type, allele_type); + args->calc_ac = 1; + break; + } + case 'C': + { + args->max_ac_type = ALLELE_NONREF; + if ( sscanf(optarg,"%d:%s",&args->max_ac, allele_type)!=2 && sscanf(optarg,"%d",&args->max_ac)!=1 ) + error("Error: Could not parse --max-ac %s\n", optarg); + set_allele_type(&args->max_ac_type, allele_type); + args->calc_ac = 1; + break; + } + case 'q': + { + args->min_af_type = ALLELE_NONREF; + if ( sscanf(optarg,"%f:%s",&args->min_af, allele_type)!=2 && sscanf(optarg,"%f",&args->min_af)!=1 ) + error("Error: Could not parse --min_af %s\n", optarg); + set_allele_type(&args->min_af_type, allele_type); + args->calc_ac = 1; + break; + } + case 'Q': + { + args->max_af_type = ALLELE_NONREF; + if ( sscanf(optarg,"%f:%s",&args->max_af, allele_type)!=2 && sscanf(optarg,"%f",&args->max_af)!=1 ) + error("Error: Could not parse --min_af %s\n", optarg); + set_allele_type(&args->max_af_type, allele_type); + args->calc_ac = 1; + break; + } + + case 'x': args->private_vars |= FLT_INCLUDE; args->calc_ac = 1; break; + case 'X': args->private_vars |= FLT_EXCLUDE; args->calc_ac = 1; break; + case 'u': args->uncalled |= FLT_INCLUDE; args->calc_ac = 1; break; + case 'U': args->uncalled |= FLT_EXCLUDE; args->calc_ac = 1; break; + case 'p': args->phased |= FLT_INCLUDE; break; // phased + case 'P': args->phased |= FLT_EXCLUDE; break; // exclude-phased + case 'g': + { + if ( !strcasecmp(optarg,"hom") ) args->gt_type = GT_NEED_HOM; + else if ( !strcasecmp(optarg,"het") ) args->gt_type = GT_NEED_HET; + else if ( !strcasecmp(optarg,"miss") ) args->gt_type = GT_NEED_MISSING; + else if ( !strcasecmp(optarg,"^hom") ) args->gt_type = GT_NO_HOM; + else if ( !strcasecmp(optarg,"^het") ) args->gt_type = GT_NO_HET; + else if ( !strcasecmp(optarg,"^miss") ) args->gt_type = GT_NO_MISSING; + else error("The argument to -g not recognised. Expected one of hom/het/miss/^hom/^het/^miss, got \"%s\".\n", optarg); + break; + } + case 9 : args->n_threads = strtol(optarg, 0, 0); break; + case 8 : args->record_cmd_line = 0; break; + case '?': usage(args); + default: error("Unknown argument: %s\n", optarg); + } + } + + if ( args->filter_logic == (FLT_EXCLUDE|FLT_INCLUDE) ) error("Only one of -i or -e can be given.\n"); + if ( args->private_vars > FLT_EXCLUDE ) error("Only one of -x or -X can be given.\n"); + if ( args->uncalled > FLT_EXCLUDE ) error("Only one of -u or -U can be given.\n"); + if ( args->phased > FLT_EXCLUDE ) error("Only one of -p or -P can be given.\n"); + + if ( args->sample_names && args->update_info) args->calc_ac = 1; + + char *fname = NULL; + if ( optind>=argc ) + { + if ( !isatty(fileno((FILE *)stdin)) ) fname = "-"; // reading from stdin + else usage(args); + } + else fname = argv[optind]; + + // read in the regions from the command line + if ( args->regions_list ) + { + if ( bcf_sr_set_regions(args->files, args->regions_list, regions_is_file)<0 ) + error("Failed to read the regions: %s\n", args->regions_list); + } + else if ( optind+1 < argc ) + { + int i; + kstring_t tmp = {0,0,0}; + kputs(argv[optind+1],&tmp); + for (i=optind+2; ifiles, tmp.s, 0)<0 ) + error("Failed to read the regions: %s\n", tmp.s); + free(tmp.s); + } + if ( args->targets_list ) + { + if ( bcf_sr_set_targets(args->files, args->targets_list, targets_is_file, 0)<0 ) + error("Failed to read the targets: %s\n", args->targets_list); + } + + if ( bcf_sr_set_threads(args->files, args->n_threads)<0 ) error("Failed to create threads\n"); + if ( !bcf_sr_add_reader(args->files, fname) ) error("Failed to open %s: %s\n", fname,bcf_sr_strerror(args->files->errnum)); + + init_data(args); + bcf_hdr_t *out_hdr = args->hnull ? args->hnull : (args->hsub ? args->hsub : args->hdr); + if (args->print_header) + bcf_hdr_write(args->out, out_hdr); + else if ( args->output_type & FT_BCF ) + error("BCF output requires header, cannot proceed with -H\n"); + + int ret = 0; + if (!args->header_only) + { + while ( bcf_sr_next_line(args->files) ) + { + bcf1_t *line = args->files->readers[0].buffer[0]; + if ( line->errcode && out_hdr!=args->hdr ) error("Undefined tags in the header, cannot proceed in the sample subset mode.\n"); + if ( subset_vcf(args, line) ) + bcf_write1(args->out, out_hdr, line); + } + ret = args->files->errnum; + if ( ret ) fprintf(stderr,"Error: %s\n", bcf_sr_strerror(args->files->errnum)); + } + hts_close(args->out); + destroy_data(args); + bcf_sr_destroy(args->files); + free(args); + return ret; +} diff --git a/vcmp.c b/vcmp.c new file mode 100644 index 0000000..8d04b89 --- /dev/null +++ b/vcmp.c @@ -0,0 +1,132 @@ +/* vcmp.c -- reference allele utility functions. + + Copyright (C) 2013 Genome Research Ltd. + + Author: Petr Danecek + +Permission is hereby granted, free of charge, to any person obtaining a copy +of this software and associated documentation files (the "Software"), to deal +in the Software without restriction, including without limitation the rights +to use, copy, modify, merge, publish, distribute, sublicense, and/or sell +copies of the Software, and to permit persons to whom the Software is +furnished to do so, subject to the following conditions: + +The above copyright notice and this permission notice shall be included in +all copies or substantial portions of the Software. + +THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE +AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER +LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, +OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN +THE SOFTWARE. */ + +#include +#include +#include +#include +#include +#include "vcmp.h" + +struct _vcmp_t +{ + char *dref; + int ndref, mdref; // ndref: positive when ref1 longer, negative when ref2 is longer + int nmatch; + int *map, mmap; +}; + +vcmp_t *vcmp_init() +{ + return (vcmp_t*)calloc(1,sizeof(vcmp_t)); +} + +void vcmp_destroy(vcmp_t *vcmp) +{ + free(vcmp->map); + free(vcmp->dref); + free(vcmp); +} + +int vcmp_set_ref(vcmp_t *vcmp, char *ref1, char *ref2) +{ + vcmp->ndref = 0; + + char *a = ref1, *b = ref2; + while ( *a && *b && toupper(*a)==toupper(*b) ) { a++; b++; } + if ( !*a && !*b ) return 0; + if ( *a && *b ) return -1; // refs not compatible + + int i; + if ( *a ) // ref1 is longer + { + vcmp->nmatch = b-ref2; + while ( *a ) a++; + vcmp->ndref = (a-ref1) - vcmp->nmatch; + hts_expand(char,vcmp->ndref+1,vcmp->mdref,vcmp->dref); + for (i=0; indref; i++) vcmp->dref[i] = toupper(ref1[vcmp->nmatch+i]); + vcmp->dref[vcmp->ndref] = 0; + return 0; + } + + // ref2 is longer + vcmp->nmatch = a-ref1; + while ( *b ) b++; + vcmp->ndref = (b-ref2) - vcmp->nmatch; + hts_expand(char,vcmp->ndref+1,vcmp->mdref,vcmp->dref); + for (i=0; indref; i++) vcmp->dref[i] = toupper(ref2[vcmp->nmatch+i]); + vcmp->dref[vcmp->ndref] = 0; + vcmp->ndref *= -1; + return 0; +} + +int vcmp_find_allele(vcmp_t *vcmp, char **als1, int nals1, char *al2) +{ + int i, j; + for (i=0; indref ) + { + if ( !*a && !*b ) break; // found + continue; + } + + // the prefixes match + if ( *a ) + { + if ( vcmp->ndref<0 ) continue; + for (j=0; jndref; j++) + if ( !a[j] || toupper(a[j])!=vcmp->dref[j] ) break; + if ( j!=vcmp->ndref || a[j] ) continue; + break; // found + } + + if ( vcmp->ndref>0 ) continue; + for (j=0; j<-vcmp->ndref; j++) + if ( !b[j] || toupper(b[j])!=vcmp->dref[j] ) break; + if ( j!=-vcmp->ndref || b[j] ) continue; + break; // found + } + if (i==nals1) return -1; + return i; +} + + +int *vcmp_map_ARvalues(vcmp_t *vcmp, int n, int nals1, char **als1, int nals2, char **als2) +{ + if ( vcmp_set_ref(vcmp,als1[0],als2[0]) < 0 ) return NULL; + + vcmp->map = (int*) realloc(vcmp->map,sizeof(int)*n); + + int i, ifrom = n==nals2 ? 0 : 1; + for (i=ifrom; imap[i-ifrom] = vcmp_find_allele(vcmp, als1+ifrom, nals1-ifrom, als2[i]); + } + return vcmp->map; +} + diff --git a/vcmp.h b/vcmp.h new file mode 100644 index 0000000..0317704 --- /dev/null +++ b/vcmp.h @@ -0,0 +1,62 @@ +/* vcmp.h -- reference allele utility functions. + + Copyright (C) 2013-2014 Genome Research Ltd. + + Author: Petr Danecek + +Permission is hereby granted, free of charge, to any person obtaining a copy +of this software and associated documentation files (the "Software"), to deal +in the Software without restriction, including without limitation the rights +to use, copy, modify, merge, publish, distribute, sublicense, and/or sell +copies of the Software, and to permit persons to whom the Software is +furnished to do so, subject to the following conditions: + +The above copyright notice and this permission notice shall be included in +all copies or substantial portions of the Software. + +THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE +AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER +LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, +OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN +THE SOFTWARE. */ + +#ifndef __VCMP_H__ +#define __VCMP_H__ + +typedef struct _vcmp_t vcmp_t; + +vcmp_t *vcmp_init(void); +void vcmp_destroy(vcmp_t *vcmp); + +/* + * vcmp_set_ref() - sets and compares reference alleles + * Returns 0 on success or -1 if alleles not compatible + */ +int vcmp_set_ref(vcmp_t *vcmp, char *ref1, char *ref2); + +/* + * vcmp_find_allele() + * @param als1: alternate alleles to ref1 above + * @param al2: alternate allele to ref2 above + * Returns -1 if not found or 0-based index to als1 of matching allele + */ +int vcmp_find_allele(vcmp_t *vcmp, char **als1, int nals1, char *al2); + +/* + * vcmp_map_ARvalues() - Create mapping for Number=A,R tag values + * @param number: nals2 for Number=R, nals2-1 for Number=A + * @param nals1: number of alleles + * @param als1: alleles + * + * Returns pointer to an array of size nals2 with mapping from als2 + * to als1 or NULL if REFs (als1[0] and als2[0]) are not compatible. + * If i is the index of an allele in als2, ret[i] is the index of matching + * allele in als1 or -1 if als2 does not have a matching allele. + * The caller must not free the array. + */ +int *vcmp_map_ARvalues(vcmp_t *vcmp, int number, int nals1, char **als1, int nals2, char **als2); + + +#endif diff --git a/version.c b/version.c new file mode 100644 index 0000000..00eeb5a --- /dev/null +++ b/version.c @@ -0,0 +1,55 @@ +/* version.c -- report version numbers for plugins. + + Copyright (C) 2014 Genome Research Ltd. + + Author: Petr Danecek + +Permission is hereby granted, free of charge, to any person obtaining a copy +of this software and associated documentation files (the "Software"), to deal +in the Software without restriction, including without limitation the rights +to use, copy, modify, merge, publish, distribute, sublicense, and/or sell +copies of the Software, and to permit persons to whom the Software is +furnished to do so, subject to the following conditions: + +The above copyright notice and this permission notice shall be included in +all copies or substantial portions of the Software. + +THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL +THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER +LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING +FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER +DEALINGS IN THE SOFTWARE. */ + +#include +#include +#include +#include +#include "bcftools.h" +#include "version.h" + +void version(const char **bcftools_version, const char **htslib_version) +{ + *bcftools_version = BCFTOOLS_VERSION; + *htslib_version = hts_version(); +} + +void error(const char *format, ...) +{ + va_list ap; + va_start(ap, format); + vfprintf(stderr, format, ap); + va_end(ap); + exit(-1); +} + +const char *hts_bcf_wmode(int file_type) +{ + if ( file_type == FT_BCF ) return "wbu"; // uncompressed BCF + if ( file_type & FT_BCF ) return "wb"; // compressed BCF + if ( file_type & FT_GZ ) return "wz"; // compressed VCF + return "w"; // uncompressed VCF +} + + -- 2.30.2